bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Pharmaceutically Active Antibiotics on Gut Metagenome of Mother and Infant
Authors: Yadav Ruchi
Published: December 2024

BACKGROUND:

Metagenomics plays a vital role in studying microbial genomes and their implications for human health. The human gut microbiome begins to develop at birth and is shaped by factors such as maternal nutrition and antibiotic exposure. Disruptions in this microbial community can impact an infant’s immune system, metabolism, and susceptibility to various diseases. This research aims to predict the taxonomic and functional profiling of the gut metagenome in mothers and infants exposed to antibiotics. The study utilized gut metagenomic samples retrieved from the European nucleotide archive database under accession number PRJNA698986. Four samples were analyzed, including two maternal gut metagenome samples and two corresponding infant samples. The design focuses on a comprehensive assessment of microbial diversity and functional pathways using advanced bioinformatics for detailed taxonomic classification and functional analysis of the metagenomic data.

MATERIALS AND METHODS:

Taxonomic analysis was conducted using MetaPhlAn2 to extract and analyze community structure. Functional analysis was performed with HUMAnN2 to evaluate community functions.

RESULTS:

Metagenomic analysis revealed significant differences in microbial communities between infants and their mothers. The infants’ initial gut microbiome exhibited a diverse presence of both bacteria and viruses, whereas maternal samples predominantly contained bacteria, with a minor representation of archaea.

CONCLUSIONS:

This study highlights the impact of antibiotic exposure on the gut metagenome of infants, illustrating distinct differences in microbial community composition compared to mothers. The findings emphasize the need for further research to understand the functional roles of these microbial communities in health and disease.
Synergistic Nutraceutical Effects of Aqueous Extracts from Vernonia amygdalina and Moringa oleifera: A Promising Therapeutic Strategy for Gastric Ulcer Management
Authors: Kehinde Adedapo Olajide , Ekundina Victor Olukayode , Iyiola Sina , Avwioro Godwin , Enye Linus Anderson
Published: December 2024

BACKGROUND:

Gastric ulcers pose a significant health challenge globally, leading to morbidity and impacting quality of life. These ulcers result from the erosion of the gastric lining, compromising its role as the body’s first defense against pathogens. Traditional treatments often come with side effects and high costs, prompting a shift toward herbal remedies as viable nutraceutical options. This study investigates the combined nutraceutical effects of aqueous extracts from Vernonia amygdalina (bitter leaf) and Moringa oleifera (drumstick tree) to evaluate their potential in enhancing gastric mucosal protection.

MATERIALS AND METHODS:

A total of 35 Wistar rats were assigned to seven groups. The first group served as a control, receiving only standard feed and water, while the remaining groups were administered a single dose of indomethacin (40 mg/kg) to induce gastric ulcers. Following ulcer induction, various treatments were applied, including standard care with omeprazole and different doses of the herbal extracts. After 21 days, the rats were euthanized, and gastric tissues were collected for analysis.

RESULTS:

The study revealed significant healing of the gastric mucosa in rats treated with the combined extracts of Vernonia amygdalina and M. oleifera. Histological examination showed marked restoration of tissue integrity and a reduction in ulcer indices, suggesting a synergistic effect of the two herbs in promoting gastric health.

CONCLUSION:

The findings support the hypothesis that the combination of V. amygdalina and M. oleifera offers a promising dietary therapy for gastric ulcers, highlighting the potential of herbal medicine in strategic healthcare approaches for gastrointestinal disorders.
Characterization of Bacterial Isolates from Various Types of Neonatal Sepsis Cases along with Their Antibiogram Profiling
Authors: Ferdous Khaleda , Sultana Raquiba , Alam Seemi Tasnim , Supti Mahima Hossain , Jabin Tasnim , Tisha Rowson Habiba , Supti Jannatul Ferdose , Sultana Sadiya , Islam Jahidul , Uddin Md. Aftab
Published: December 2024

BACKGROUND:

Neonatal sepsis is one of the most common causes of mortality in the neonatal intensive care unit (NICU). There are regional differences in the range of pathogens that cause newborn sepsis within developing nations. In order to effectively treat neonatal sepsis, one must be aware of the bacterial agents and their pattern of antibiotic susceptibility.

MATERIALS AND METHODS:

This was a cross-sectional observational study in which samples were collected from the NICU of a tertiary care hospital in Dhaka City, Bangladesh, between the periods of February 2023 to December 2023.

RESULTS:

The study showed that among the 100 neonates, 52% were positive culture while 48% were negative. Male neonates were higher in ratio than female neonates, while the result was vice versa for the negative group. Both preterm (Group 1) and term (Group 2) neonates were infected mostly by Gram-negative Acinetobacter spp. and Pseudomonas spp. Highest susceptibility of the bacterial isolates was observed against Colistin, Klarcid, Tigecyclin, Kacin, Tazocilin, and Vancomycin. However, antibiotic Polymixin B was not an appropriate choice for both groups of neonates as the organisms showed the highest resistance pattern against this antibiotic.

CONCLUSION:

The study found that a significant portion of the bacterial isolates causing neonatal sepsis was found to be multidrug-resistant, showing the need for developing a proper antibiotic prescribing policy and its effective implementation could be a milestone for bringing a revolution in combatting the field of antibiotic resistance.
Vaginal Yeast Infections: Causes, Symptoms, Diagnosis, and Treatment
Authors: Mishra Vaishnavi H.
Published: December 2024

Vaginal yeast infection, or vaginal candidiasis, is a common condition caused by the overgrowth of the yeast Candida albicans. Approximately 75% of women will experience at least one episode in their lifetime. Candida species, especially C. albicans, typically exist as part of the normal vaginal flora but can proliferate due to various triggers, such as antibiotic use, hormonal changes, or weakened immune systems. The infection presents with symptoms such as itching, burning, white discharge resembling cottage cheese, and discomfort during sexual intercourse. Diagnosis typically involves a pelvic examination, and treatment ranges from over-the-counter antifungal creams to prescription medications like fluconazole. Home remedies, such as applying yogurt or using probiotics, have gained popularity, though their efficacy is not consistently supported by clinical evidence. The potential complications of untreated infections include recurrent episodes, pelvic inflammatory disease, and in rare cases, increased susceptibility to sexually transmitted infections. Effective prevention strategies include avoiding douching, wearing breathable cotton underwear, and maintaining balanced vaginal flora. This communication focuses on the causes, symptoms, diagnosis, treatment, and preventive measures for vaginal yeast infection, emphasizing the need for accurate diagnosis and appropriate treatment to prevent recurrence and complications.
Toxoplasma Gondii: Examining Lifecycle, Risk Factors, and Strategies for Public Health Management
Authors: Mishra Vaishnavi H. , Tiwari Anjali P
Published: December 2024

Toxoplasma gondii, is a facultatively heteroxenous, polyxenous protozoon that has developed several potential transmission routes within and between different host species. The opportunistic protozoan T. gondii is the primary cause of toxoplasmosis, a disease that affects humans and most other mammals. The gundis reside in the foothills and mountains of southern Tunisia and were frequently used to investigate Leishmania at the Pasteur Institute in Tunis. T. gondii infection can have varying impacts on human health, depending on factors such as the individual’s immune status and the strain of the parasite. Pregnant women are uniquely vulnerable to T. gondii infection, as the parasite can traverse the placental barrier and infect the developing foetus, leading to congenital toxoplasmosis. Preventing T. gondii infection in animals is multifaceted and involves measures that target intermediate and definitive hosts. Collaboration among healthcare professionals, veterinarians, and public health authorities is important to reducing the global burden of toxoplasmosis.
1. Study designs for making most of the limited resources
Authors: Indrayan A
Published: December 2024

Medical research is costly and requires significant effort. While intracellular research hardly follows a formal design, most data-based studies require a structural approach for optimal utilization of resources. Depending on the study’s objectives and available resources, as well as the aim to obtain valid and reliable results, the design may be descriptive, employing specific sampling strategies, or analytical, exploring antecedent-outcome relationships. Analytical studies often involve designs such as randomization and blinding in clinical trials, and may use prospective, retrospective, or cross-sectional designs in observational studies. This first article in the series on biostatistics methods specifies the essential features of each design and describes the contexts in which they are most appropriate.
Controversies around the treatment of peritoneal metastases of colorectal cancer
Authors: Morera-Ocon Francisco J , Navarro-Campoy Clara , Guastella Ticiano , Landete-Molina Francisco
Published: December 2024

In this editorial we examine the article by Wu et al published in the World Journal of Gastrointestinal Oncology . Surgical resection for peritoneal metastases from colorectal cancer (CRC) has been gradually accepted in the medical oncology community. A randomized trial (PRODIGE 7) on cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) failed to prove any benefit of oxaliplatin in the overall survival of patients with peritoneal metastases from colorectal origin. Nevertheless, isolated systemic chemotherapy for CRC stage IV has demonstrated a reduced response in peritoneal metastases than that obtained in other metastatic sites such as the liver. Another tool is required in those patients to achieve more local control of the disease. Surgical groups in peritoneal surgery continue to use HIPEC in their procedures, using other agents than oxaliplatin for peritoneal cavity infusion, such as mitomycin C. These patients present with complex surgical issues to manage, and consequently a large burden of complications has to be anticipated. Therefore, identifying patients who will benefit from CRS with or without HIPEC would be of great interest.
Exosomes as promising frontier approaches in future cancer therapy
Authors: Chew Fatt-Yang , Tsai Chin-Hung , Chang Kuang-Hsi , Chang Yu-Kang , Chou Ruey-Hwang , Liu Yi-Jui
Published: December 2024

In this editorial, we will discuss the article by Tang et al published in the recent issue of the World Journal of Gastrointestinal Oncology . They explored an innovative approach to enhancing gemcitabine (GEM) delivery and efficacy using human bone marrow mesenchymal stem cells (HU-BMSCs)-derived exosomes. The manufacture of GEM-loaded HU-BMSCs-derived exosomes (Exo-GEM) has been optimized. The Tang et al ’s study demonstrated that Exo-GEM exhibits enhanced cytotoxicity and apoptosis-inducing effects compared to free GEM, highlighting the potential of exosome-based drug delivery systems as a more effective and targeted approach to chemotherapy in pancreatic cancer. Additional in vivo studies are required to confirm the safety and effectiveness of Exo-GEM before it can be considered for clinical use.
TRIPLET combined with microwave ablation: A novel treatment for advanced hepatocellular carcinoma
Authors: Zhao Fei-Yu , Si Guo-Wei , Qian Nian-Song
Published: December 2024

This editorial comments on a study by Zuo et al . The focus is on the efficacy of hepatic arterial infusion chemotherapy combined with camrelizumab and apatinib (the TRIPLET regimen), alongside microwave ablation therapy, in treating advanced hepatocellular carcinoma (HCC). The potential application of this combination therapy for patients with advanced HCC is evaluated.
Advancing treatment strategies: Insights from network meta-analysis of hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma
Authors: Cheng Chun-Han , Hao Wen-Rui , Cheng Tzu-Hurng
Published: December 2024

This study examines the pivotal findings of the network meta-analysis of Zhou et al , which evaluated the efficacy of hepatic arterial infusion chemotherapy and combination therapies for advanced hepatocellular carcinoma (HCC). This meta-analysis suggests that therapeutic combinations have greater efficacy than do standard treatments. The article highlights the key insights that have the potential to shift current clinical practice and enhance outcomes for patients with advanced HCC. Additionally, this article discusses further research that can be conducted to optimize these treatments and achieve personalized care for patients with HCC.
Colon capsule endoscopy: Can it contribute to green endoscopy?
Authors: Nakaji Konosuke
Published: December 2024

Climate change due to sustained carbon dioxide (CO2) emissions poses a serious threat to human existence, such as extreme weather events that must be addressed in all sectors of society. Gastrointestinal endoscopy is a healthcare sector that produces high levels of CO2 emissions. Colonoscopy (CS) is the gold standard for colorectal cancer (CRC) screening that reduces the number of CRC-related deaths. However, vast amounts of cleaning solutions used to disinfect the colonoscope are disposed of, and multiple nonrenewable wastes are generated in performing CS, which significantly impact the environment. Currently, colon capsule endoscopy (CCE) retains good accuracy and has excellent potential to reduce CO2 emission through a simple procedure. However, to date, colon capsules are single-use and lack a clear collection pathway. In addition, there is a lack of specific data regarding the environmental impact of CCE. Further research is needed to prove that CCE is a more environmentally friendly tool than CS.
Physical and psychological symptoms and survey importance in celiac disease
Authors: Ciaccio Edward J , Lee Anne R , Lebovits Jessica , Wolf Randi L , Lewis Suzanne K
Published: December 2024

Celiac disease is an autoimmune condition that affects approximately 1% of the worldwide community. Originally thought to be confined mostly to the small intestine, resulting in villous atrophy and nutrient malabsorption, it has more recently been implicated in systemic manifestations as well, particularly when undiagnosed or left untreated. Herein, the physical and psychological symptoms of celiac disease are described and explored. An emphasis is placed on efforts to query prospective and confirmed celiac disease patients via the use of surveys. Suggestions are made regarding the development of efficacious surveys for the purpose of screening for celiac disease in undiagnosed persons, and monitoring efficacy of the gluten-free diet in persons diagnosed with celiac disease. There are broad categories of physical and psychological symptoms associated with celiac disease. There is also an essential interaction between such physical and the psychological symptoms. It is important to capture the association between symptoms, via queries directed toward suspected and confirmed persons with celiac disease. The use of anonymous online surveys can be helpful to determine the qualities and characteristics which may be associated with this condition. It is suggested that personal surveys should be given a greater role in screening and to lessen the time for diagnosis. Querying the subject directly via a survey can provide clues as to the types of symptoms being experienced by those with celiac disease currently, as well as to determine the salient aspects of the symptomatology, which will be useful for rapid screening and monitoring in future work.
Endoscopic ultrasound-guided therapies in the treatment of gastric varices: An in-depth examination of associated adverse events
Authors: Manolakis Anastasios , Tsagkidou Kyriaki , Koumarelas Konstantinos Eleftherios
Published: December 2024

The Baveno VII consensus, released in 2023, recommends that the endoscopic treatment of choice for managing bleeding gastric varices (GV) is endoscopic ultrasound (EUS)-guided treatment, specifically EUS-guided cyanoacrylate (CYA) glue injection. This approach has been endorsed due to its efficacy in controlling bleeding while reducing rebleeding rates, compared to other endoscopic techniques. Despite its efficacy, CYA injection for GV has been linked to rare but serious adverse events, such as glue embolization leading to pulmonary embolism, infection/bacteremia, splenic infarction, intra-procedural and post-procedural complications. The technique for endoscopic obliteration of GV was subsequently refined using EUS guidance, aiming to more accurately direct the injection into the varix, reduce the volume of injected glue, target the perforating vein when possible, and confirm obliteration of GV via Doppler examination.
Endoscopic ultrasound guided-gastroenterostomy is the best choice in the treatment of gastric outlet obstruction
Authors: Jagielski Mateusz
Published: December 2024

First of all, I would like to congratulate Vilas-Boas et al on an interesting publication. In this letter the authors write about very interesting topics in the management of patients with malignant gastric outlet obstruction (GOO). GOO developed in up to 20% of patients with advanced hepatopancreatobiliary disease both in benign and malignant form. For this reason, the issue is very current. I fully agree with Vilas-Boas et al that technical aspect of the procedures (surgeon’s view) often differs from the patient’s view (regarding such factors as cancer-related survival, overall survival, body mass composition, nutritional biomarkers, chemotherapy tolerance and patient-reported quality of life). The mentioned factors should be taken into account when interpreting the effectiveness of treatment modalities for malignant GOO (mGOO), which should be also considered in the future studies in this subject. In my opinion, all above mentioned factors could be summarized in one term: “Improving quality of life of patients with mGOO”.
Performance Evaluation of Common Rail Direct Injection Engine Run on
Biodiesel of Used Temple Oil Using Response Surface Methodology
Authors: Shaikh Sardar Mansoor , Khandal Sanjeevkumar V.
Published: December 2024

Diesel engines produce more smoke and nitrogen oxide (NOx) emissions. Hence, one
has to develop a new technique that reduces these emissions besides works
satisfactorily with alternative fuels in place of diesel. In this work, used
temple oil biodiesel (BTO) is a candidate to replace diesel to run diesel
engine. Also, common rail direction injection (CRDi) is a technique that injects
fuel at a higher pressure than conventional injectors of diesel engines that
produce fine fuel droplets suitable for highly viscous biodiesel. This work also
uses the design of experiments (DOE) and response surface methodology (RSM)
modeling approach to evaluate the performance of CRDi engine with three
operating parameters namely injection timing (IT), injection pressure (IP), and
exhaust gas recirculation (EGR). From the study, it could be concluded that CRDi
engine showed better performance at IT of 9°bTDC, IP of 855 bar with EGR of 20%
but with little reduction in thermal efficiency. The study has reported good
agreement between predicted values and experimental results.
Enhancing Diesel Engine Performance with Silica Coated Pistons and
Cassia Fistula Biodiesel Blends: A Pathway to Cleaner and Efficient
Energy
Authors: Veeraraghavan Sakthimurugan , De Poures Melvin Victor , Madhu S. , Palani Kumaran
Published: December 2024

This study investigates the influence of Silica-Diamond-Like Carbon (Si-DLC)
coated pistons on performance metrics of diesel engine fuelled with various
blends of Cassia Fistula biodiesel (CFBD10, CFBD20, CFBD30, and CFBD40). The
primary focus is on key performance metrics, including Brake Thermal Efficiency
(BTE), Brake Specific Energy Consumption (BSEC), and Exhaust Gas Temperature
(EGT). The results demonstrated improvement in BTE and EGT, alongside a
reduction in BSEC across all biodiesel blends compared to conventional diesel.
Specifically, at full engine load, CFBD10 exhibited a BTE of 33.41%, which is
3.17% higher than neat diesel in the stock engine. At part load and no-load
scenarios, improvements of 2% and 0.51% over neat diesel were recorded. During
no-load conditions, the BSEC for CFBD10 was measured at 9.901 MJ.kW-hr, 0.738
MJ.kW-hr lower than that of neat diesel. Further increases in Cassia fistula
blends resulted in higher BSEC values due to lower calorific content. Exhaust
gas temperatures at higher loads were recorded at 330°C, 374°C, 368°C, 360°C,
and 351°C for diesel, CFBD10, CFBD20, CFBD30, and CFBD40, respectively, with
CFBD10 outperforming neat diesel by 44°C. Specifically, the Si-DLC coating
significantly contributes to improved combustion efficiency and thermal
management, resulting in higher BTE and EGT. Concurrently, the optimized
combustion process facilitated by the Si-DLC coating leads to a decrease in
BSEC, indicating a more efficient energy utilization. The scope of this research
extends to analysing the implications of Si-DLC coatings in the broader context
of automotive engine efficiency and sustainability. These findings underscore
the potential of Si-DLC coated pistons in promoting cleaner and more efficient
automotive energy solutions. The study aligns SDG 7 (Affordable and Clean
Energy) and SDG 13 (Climate Action), by advancing the development of sustainable
biodiesel technologies that enhances energy efficiency in the transportation
sector.
Machining Studies on AISI 4140 Steel as Automotive Axle and Drive
Shafts in Automobile via Numerical Simulation
Authors: Senthilkumar N.
Published: December 2024

This study focuses on machining automobile parts such as drive shafts and axles
made of low alloy steel AISI 4140. The influence of cutting inserts geometrical
parameters, viz., relief angle (RIA), rake angle (RAA), and nose radius (NA) are
studied by designing experiments using Taguchi’s methodology. Numerical
simulation is conducted using DEFORM-2D; a suitable L9 orthogonal
array (OA) is considered for this work for varying combinations of inputs, and
the resultant cutting force, maximum principal stress, and tool life are
determined. Adopting a signal-to-noise (S/N) ratio minimizes the outputs for
better machining conditions and achieves high-quality components with precision,
tolerance, and accuracy. The ideal conditions obtained from the S/N ratio are
RAA of 6°, RIA of 3°, and NR of 0.6 mm. Analysis of variance presents that the
NR influences the resultant cutting force, wear depth, and work piece damage
73.51%, RAA following by 23.99%, and RIA by 2.03% achieved with a R2
value of 99.53%.
Polyethylene Sheet Dispersion and Optical Constant Changes Due to
Electron Beam Irradiation
Authors: Kaushik Nitish , Sandeep Ch , Srinivasan V. P. , Prakash B. Vijaya , Kalaiarasan S. , Arunkumar S.
Published: December 2024

Radiation has garnered the most attention in the research that has been conducted
on polyethylene sheets. According to the calculations, there were 145892.35 kGy
in total radiation doses administered. An ultraviolet visible spectrophotometer
was used to examine the impact that electron beam irradiation had on the optical
constants. Two of the most crucial variables taken into account when calculating
the optical constants and the absorption coefficient are the reflectance and
transmittance of polyurethane sheets. Reduced light transmission through the
sheet achieves these characteristics, which are related to the transmittance and
reflectance of the Fresnel interface. Cross linking makes it more challenging
for the polyurethane molecular chains to become fixed. Both the refractive index
and the dispersion properties have been altered as a direct result of this.
Despite the fact that the doses of electron irradiation were getting lower, it
eventually rose to 105 kGy. Contrary to the cross-linking process, the rate of
polyurethane breakdown accelerated with increasing radiation doses. Irradiation
sheets showed that the material dispersion characteristics would undoubtedly
change as a result of cross-linking and deterioration. The ionizing radiation
exposure of the sheets proved that this was the case.
AI-Based Smart Vehicle Parking System
Authors: Atheef M. Syed , Sundar K. Sham , Kumar P. P. Prem , Karthika J.
Published: December 2024

This project presents the development of an advanced Autonomous Mobile Robot
(AMR) designed to autonomously lift and maneuver four-wheel drive vehicles into
parking spaces without human intervention. By leveraging cutting-edge camera and
sensor technologies, the AMR integrates LIDAR for precise distance measurements
and obstacle detection, high-resolution cameras for capturing detailed images of
the parking environment, and object recognition algorithms for accurately
identifying and selecting available parking spaces. These integrated
technologies enable the AMR to navigate complex parking lots, optimize space
utilization, and provide seamless automated parking. The AMR autonomously
detects free parking spaces, lifts the vehicle, and parks it with high
precision, making the entire parking process autonomous and highly efficient.
This project pushes the boundaries of autonomous vehicle technology, aiming to
contribute significantly to smarter and more efficient urban mobility
systems.
Electric Windshield Wiper Switch - Trucks, Buses, and Multipurpose Vehicles
Authors:   Truck and Bus Windshield Wipers and Climate Control Comm
Published: December 2024

This SAE Recommended Practice establishes for trucks, buses, and multipurpose vehicles with GVW of 4500 kg (10 000 lb) or greater:

a

Minimum performance requirements for the switch for electrically or electro-pneumatically powered windshield wiping systems.

b

Uniform test procedures that include those tests that can be conducted on uniform test equipment by commercially available laboratory facilities.

The test procedures and minimum performance requirements, outlined in this document are based on currently available engineering data.

It is the intent that all portions of the document will be periodically reviewed and revised as additional data regarding windshield wiping system performance are developed.
Truck and Bus Grade Parking Performance Test Procedure
Authors:   Truck and Bus Brake Systems Committee
Published: December 2024

This SAE Recommended Practice establishes methods to determine grade parking performance with respect to:

a

Ability of the parking brake system to lock the braked wheels.

b

The vehicle holding or sliding on the grade, fully loaded or unloaded.

c

Applied manual effort.

d

Unburnished or burnished brake lining friction conditions.

e

Down and up grade directions.
Hubungan Picky Eater dengan Tingkat Kecukupan Asupan Zat Gizi Makro dan Status Gizi di Puskesmas Wakorumba Utara
Authors: Anantha Esti , Abadi Ellyani , Ihsan M Habib
Published: December 2024

Picky eater ataupun sikap memilih-milih makanan merupakan suatu kondisi dimana anak tidak bersedia ataupun menolak untuk makan, ataupun mengalami kesusahan dalam mengkonsumsi makanan serta minuman. Penelitian ini bertujuan Untuk mengetahuiirhubungan picky eater dengan tingkat kecukupan asupan zat gizi makro di Puskesmas Wakorumba Utara Kabupaten Buton Utara. Jenis penelitian kuantitatif, dengan desain Cross Sectional Sampel pada penelitian ini yaitu 68 Balita usia 3-5 tahun di wilayah kerja Puskesmas Wakorumba Utara diperolah dengan teknik pengambilan sampel. Pengambilan data meliputi pengisian kuisioner picky eater dan tingkat kecukupan zat gizi makro di ukur menggunakan food recall, sedangkan status gizi didapatkan dari z-score berat badan/tinggi badan (BB/TB). Seluruh data dianalisis menggunakan SPSS dan uji Chi-Square. Hasil peneltian menunjukkan nilai p value variabel tingkat kecukupan asupan karbohidrat <0,01, tingkat kecukupan asupan protein 0,056, tingkat kecukupan asupan lemak 0,003, dan status gizi 0,003. Kesimpulan pada penelitian ini yaitu ada hubungan antara perilaku picky eater dengan tingkat kecukupan asupan zat gizi karbohidrat,protein,lemak dan status gizi.
Analisis Kandungan Gizi Dan Uji Organoleptik Cookies Alpusen Sebagai Snack Pada Siswa Di SDN 2 Tinanggea.
Authors: Liasambu Fhidhia Ismawati , Ananda Siti Hadrayanti , Demmalewa Jenny Qlifianti
Published: December 2024

Penelitian ini menggunakan rancangan acak lengkap (RAK) dengan satu kelompok mendapat dua perlakuan (100gr:30gr dan 80gr:50gr), ditambah pemasukan buah alpukat gersen dengan menggunakan rasio daya terima. Bentuk penelitiannya adalah eksperimen kuasi (quasi-experimental) dengan menggunakan tipe one-shot study. Dengan menggunakan sampel lengkap, terpilih 42 siswa kelas V dan VI SDN 2 Tinanggea sebagai sampel. Jumlah lemak yang diuji, vitamin C, dan vitamin A merupakan variabel terikat yang diteliti, sedangkan uji hedonik merupakan variabel bebas. Uji-t tidak berpasangan Mann Whitney (p-value = <0,05) digunakan untuk analisis dataTemuan penelitian menunjukkan ada perbedaan mencolok antara aroma dan rasa. Sementara itu, terdapat variasi penting dalam hal tekstur dan persyaratan warna. Preferensi panelis terhadap cookies dengan gersen alpukat adalah sebagai berikut: R1 sebesar 69% dari segi aroma, R2 dan R1 sebesar 100% dari segi tekstur, dan R1 sebesar 85,7% dari segi rasa. Kriteria hue adalah R2 & R1 dengan nilai 100%. Cookies alpusen memiliki nilai gizi tertinggi berupa lemak R1 (7,15 mg), vitamin C (28,34 mg), dan vitamin A (0,14 µg/g). Sehubungan dengan karakteristik rasa dan aroma, penelitian ini berpendapat bahwa menambahkan alpukat Gersen ke dalam kue mempengaruhi penerimaannya secara drastis. Dari segi kesukaan, panelis menilai warna, aroma, tekstur, dan rasa produk kue R1 cukup menarik. Sedangkan panelis menilai R2 bagus dari segi warna dan aroma. Cookies Alpusen memiliki nilai gizi tertinggi dalam hal lemak R2 (6,15 mg), vitamin C (31,65), dan vitamin A (0,22µg/g).
Gambaran Sifat Sensori dan Nilai Gizi Donat dengan Penggunaan Berbagai Jenis Gula
Authors: Marlin Fitri Selly Desi Yanti , Abadi Ellyani , Ananda Siti Hadrayanti
Published: December 2024

Donat merupakan pangan jenis bakery dimana memiliki bentuk cincin dengan lubang ditengahnya atau biasanya memiliki bentuk bundar di dalamnya terdapat isian yang memiliki rasa manis seperti krim atau selai. Jenis penelitian adalah deskriptif, Rancangan Acak Lengkap (RAL) dengan memberikan 3 jenis perlakuan penggunaan gula pada pembuatan donat, yaitu T1 = fruktosa (rose brand cair) 100 ml, T2 = sukrosa (gulaku) 100 gr, T3 = Madu (madurasa murni) 100 ml. Untuk Sampelnya 23 siswa/siswi kelas VII pada SMPN 10 Kendari yang diperoleh dengan menggunakan total sampling. Variabel yang diteliti terdiri dari variabel terikat yaitu uji kadar karbohidrat  dan lemak dan variabel bebas yaitu uji hedonik. Teknik analisa data yang digunakan adalah teknik deskriptif kuantitatif dengan menggunakan persentase. Hasil penelitian tingkat kesukaan panelis pada donat kriteria rasa yaitu T1 86,9%, warna T2 86,9%, aroma T1 dan T2  73,9%, sedangkan tekstur T2 nilai 78,2%. Kandungan gizi donat yaitu T2 Karbohidrat sebesar 53.27% sedangkan T2 Lemak sebesar 28.1%. Simpulan ada perbedaan dari donat dengan tingkat berdasarkan atribut rasa. Untuk tingkat kesukaan panelis menyukai produk donat T1 dari segi rasa, warna, aroma dan tekstur. Sedangkan segi tekstur lebih menyukai T2. Untuk kandungan gizi donat yaitu T2 Karbohidrat 53.27%, T2 Lemak  28.1%.
Status Gizi, Asupan Fe dan Kepatuhan Konsumsi Tablet Fe pada Ibu Hamil Anemia di Puskesmas Karanganyar Tasikmalaya
Authors: Listianasari Yanita , Nelnovia Felia
Published: December 2024

Anemia during pregnancy is a major health problem in developing countries with high levels of morbidity in pregnant women. This study aims to determine the nutritional status, Fe intake and compliance with the consumption of Fe tablets in anemic pregnant women at the Karanganyar Tasikmalaya Community Health Center. This type of research is descriptive research with a cross sectional design. The sample of 62 people consisted of 31 anemic pregnant women and 31 non anemic pregnant women. The data collected includes data on the nutritional status of pregnant women, Fe intake of pregnant women and compliance with consuming Fe tablets. The research results showed that the majority of pregnant women’s nutritional status was not KEK (83,9%). The nutritional status of pregnant women is not-anemic, all of them (100%) have a nutritional status that is not KEK. The Fe intake of anemic pregnant women is 100% included in the severe deficit category and the Fe intake of non-anemic pregnant women is 23 people (74,2%) have a severe deficit. Some anemic pregnant women did not comply with taking Fe tablets (64,5%). Pregnant women are not anemic, most of them adhere to taking Fe tablets (61,3%). The conclusion is that the majority of anemic pregnant women have a nutritional status that is not KEK, pregnant women who are not anemic have a nutritional status that is not KEK. All anemic pregnant women have a severe Fe intake deficit, pregnant women who are not anemic have a severe Fe intake deficit. Most anemic pregnant women do not comply with taking Fe tablets, most non anemic pregnant women comply with taking Fe tablets. It is hoped that anemic and non-anemic pregnant women will improve their diet to 3 times a day with a balanced nutritional menu
Studi Pembuatan Minyak Gamat dari Teripang Laut (Holothuroidea) Dalam Rangka Meningkatkan Nilai UMKM Masyarakat Pulau Ngenang
Authors: Oktaviani Fifin , Candra Heldi , Muliana Hilda , Kusumawati Aldhehita Ari , Hidayati Hidayati , Ulinnuha Anisa , Istiqomah Iffah Nur , Agustina Nurul
Published: December 2024

Indonesia merupakan negara kepulauan yang memiliki banyak perairan dan telah diakui dunia internasional. Obat-obatan dari laut merupakan prospek yang cerah dalam menanggulangi semakin bertambahnya penyakit. Kegiatan ini dilakukan di Pulau Ngenang, Kota Batam dengan edukasi metode kuantitatif kalibrasi bahan untuk produksi produk. Berdasarkan hasil analisis dapat disimpulkan bahwa dari Teripang laut (Holothuroidea) ditambahkan dengan bahan ramuan herbal seperti minyak kelapa murni, jahe, kunyit dan bahan lainnya  dapat dijadikan sebagai minyak yang dapat menyembuhkan penyakit gatal-gatal, luka, nyeri sendi, keseleo, dan bisa digunakan sebagai minyak urut. Kegiatan ini bertujuan untuk Studi pembelajaran Pembuatan Minyak Gamat dari Teripang Laut (Holothuroidea) dalam meningkatkan pengetahuan dosen dan mahasiswa dalam memproduksi minyak gamat serta membantu meningkatkan nilai ekonomi UMKM Masyarakat Pulau Ngenang.
Pelatihan dan Pendampingan Pembuatan Mie Daun Kelor untuk Meningkatkan Gizi dan Ekonomi Masyarakat di Desa Palongan Kecamatan Bluto Kabupaten Sumenep
Authors: Hopid Hopid , Hamzah Amir , Rahman Sindi Arista , Wahyuni Purwati Ratna , Santosa Ribut
Published: December 2024

Daun kelor tersebar di wilayah Kabupaten Sumenep terutama di lahan tegalan yang sengaja ditanam pinggir lahan dengan produksi yang melimpah dan belum dimanfaatkan secara maksimal untuk meningkatkan gizi pangan dan ekonomi masyarakat. Pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan tentang manfaat daun kelor, memperkenalkan mie daun kelor sebagai pangan alternatif yang lebih sehat dan bergizi serta untuk menambah penghasilan masyarakat. Metode kegiatan ini terdiri dari persiapan, pelaksanaan (penyuluhan dan praktek) dan evaluasi. Hasil pengabdian menunjukkan antusiasme dan minat masyarakat sangat tinggi dalam mengikuti kegiatan pelatihan, peserta mendapat pengetahuan dan keterampilan tentang cara pembuatan mie daun kelor yang penuh gizi dan nutrisi yang sangat baik dan berguna bagi kesehatan serta dapat membuka usaha kuliner mie berbahan  baku daun kelor.
A különírás és az egybeírás tanításának a módszertana
Authors: Antalné Szabó Ágnes
Published: December 2024

A tanulmány témája a különírás és az egybeírás témakörének a módszertani feldolgozása. A tanulmány röviden utal az elméleti alapokra, majd lépésről lépésre egy tanulói tevékenységekre épülő, induktív tanulás- és tanításmódszertani utat mutat be az alárendelő szóösszetételek helyesírási szabályaihoz kapcsolódva. A tanulás támogatására helyesírási táblázatokat, folyamatábrákat és hierarchikus fürtábrákat is ajánl.
Adalékok az -i képzős földrajzi nevek helyesírásához
Authors: Kiss Magdaléna
Published: December 2024

A tanulmány témája az -i melléknévképzős földrajzi nevek helyesírás-gyakorlatának bemutatása, amelynek két fő része a helyesírási osztályozás felvázolása és az írásban való alkalmazás értékelése. Az első egységben a helyesírási szabályzat alapján az egybeírás, a kötőjeles írásmód és a különírás esetei jelennek meg. A második blokkban egy 9–12. osztályos diákok által kitöltött és visszaküldött kérdőív válaszainak összesítése tartalmazza a helyesen írt szavak arányát, ill. a kitöltők által nehezebbnek ítélt formákat.
The Subject: Challenges of the Digital
Authors: Trufanova Elena O.
Published: December 2024

The article deals with the problem of the influence of digitalization processes on the concept of a subject. The purpose of the study is to analyze this influence and substantiate the possibility of preserving the category of the subject in the philosophical understanding of the present world and human being. It is shown that the expansion of human activity into the digital environment creates a situation in which the possibility of the existence of a subject as an integrity is questioned, since human activity is distributed across two environments — physical and digital. Several key problematic points are considered that make it necessary to clarify understanding of the subject in the modern world — these are the “disembodied” subject in the digital environment, the “decentralization” of the subject (i.e., the distribution of his activities in two different environments) and the alienation of information about the subject and messages belonging to it in the digital environment. It is revealed that at the heart of all these three problems, in one way or another, there is a gap between the bodily being of a person and its manifestations in the digital world, and it is demonstrated that the “incorporeality” of the subject in the digital world is illusory. It shows how a number of authors begin to use the concept of a “digital subject” to solve the above-mentioned problems and concludes that the use of such a term is possible only as a metaphor, since it hints at the existence of a certain separate entity in the digital world, whereas the subject cannot be considered in complete isolation from the physical environment. It is concluded that the distribution of human activity in the physical and digital environment is not the reason for the rejection of the concept of the subject. It is shown that the modern understanding of the subject is possible with a combination of approaches of body-oriented cognition and narrative approach, where the first is associated with the embodied being of the subject in the physical environment, and the second not only reflects the being of the subject in the digital environment, but also serves as a link between the digital and physical aspects of the subject. The combination of these two approaches allows us to preserve the idea of the integrity of the subject.
A New Aspect in Analysis and Improvement of Standalone Solar-Driven Absorption Refrigeration Systems
Authors: Osman Wageiallah Mohammed  , Fathelrahman Ahmed Elmahi
Published: December 2024

Solar-driven absorption refrigeration systems (ARSs) are subjected to work under off-design conditions due to the driving temperature variation. In this study, a model of NH3/H2O ARS with 100-kW cooling capacity has been developed. Energetic and exergetic coefficients of performance (COP, ECOP), besides cooling production (Qeva), have been investigated at off-design conditions. The analysis indicates a reduction in the effectiveness of the generator and solution heat exchanger (SHX) under such conditions. A new method to improve the off-design system’s performance by modifying the generator and SHX heat capacities is suggested. Results revealed that an increase in heat capacities of the generator and SHX (UAgen, UASHX) effectively improves the system’s performance. Raising the values of UAgen and UASHX by 20% maintains the system’s COP, ECOP, and Qeva near their designed values under a wider range of driving temperatures (100 oC to 92 oC). Moreover, this adjustment helps decrease the system’s cut-in/off temperature.
Enabling Principal Leadership for Teacher Well-Being Through African Voices Dialogue Platform
Authors: Munger Shanel Donna , Yassim Kathija , Olumuyiwa Omotosho Ademola
Published: December 2024

The COVID-19 epidemic had a huge influence on schools, requiring more interconnected, diverse, and digital leadership. Because of the pandemic's severe social distance and lockdowns, many school leaders felt alone. African Voices Dialogue (AVD), an online platform, provided a virtual space for school leaders to interact and exchange information and perspectives. The study concentrated on the use of AVD as a method for fostering discourse and action about teacher well-being. The study made use of a qualitative case study research design, which included two Limpopo primary school leaders and one teacher from each school. The results suggest that the pandemic had a significant effect on the well-being of teachers. However, the AVD platform has allowed school leaders to engage in dialogue around important teacher well-being issues and provided support in leading teacher well-being during these challenging times. This has cultivated a sense of being part of a community by exchanging valuable information and insights. Consequently, it has aided school leaders in creating customized coping strategies according to their specific requirements. The research demonstrated that online platforms are valuable tools for establishing arenas where African school leaders can interact, progressing from mere conversations to tangible initiatives within their respective local schools.
Incessant School Closure and Quality of Learning in Universities
Authors: Fasanmi Success Ayodeji
Published: December 2024

The learning process at any level of education is expected to be smooth, stable and sustainable. This largely determines the effectiveness and quality of such a learning process. This study investigated the influence of incessant closure on the quality of learning in Nigerian universities. This study was hinged on the Behaviourist Theory of Learning which was considered most suitable. The descriptive survey research design was adopted for this study. Obafemi Awolowo University, Nigeria was purposively selected because the university has one of the highest incidences of disruption of academic activities in the country. Six faculties were selected out of the existing thirteen faculties while 360 students (60 from each faculty) were selected for the study. A self-designed and validated questionnaire was used to collect data for the study. The data collected were analysed using inferential statistics. The findings of this study showed that unresolved industrial disputes and students’ protest are the main causes of the frequent closure of universities which over the years have had negative influence on the quality of learning in Nigeria Universities. The study recommended the need for improved funding of the education sector, especially higher education which is critical for the development of any nation.
The Effect of Using Plastic Waste as a Media for Making Handicrafts in Grade IV Fine Arts Learning to Increase Student Creativity at Petompon 02 Elementary School
Authors: Safitri Nahdya Nurul , Nurharini A , Gunadi  , Avifah Ianatul
Published: December 2024

The main problem is lack education of students, especially class IV SDN Petompon 02 regarding the proper and correct disposal and use waste, especially plastic waste. Research was carried out by giving pretest questions to control and experimental classes before giving treatment to  experimental class, the end of lesson they were given post-test questions after being given treatment the experimental class, data collection was also taken from questionnaires that had been filled by students. Results this research show the increase in student creativity is high category , meaning use plastic waste as a medium for making handicrafts is effectively used in learning to increase student creativity in craft materials from plastic waste. The novelty of this research is fun learning not only increases students' creativity utilizing plastic waste, but also increases the creativity and artistic spirit of class IV students making crafts from plastic waste student creativity. The results of this research, can help readers find out methods and benefits, as well as the importance reprocessing waste into various forms crafts. This research aims to determine student activities and test effectiveness using plastic waste as medium for making handicrafts to increase activity of class IV students SD Negeri Petompon 02.
Perancangan Aplikasi Berbasis Web untuk Penentuan Penjual di PT Bahtera Multi Cemerlang dengan Algoritma TOPSIS
Authors: Allvi Reyner , Bororing Grace Martha Geertruida
Published: December 2024

The rapid development of information and communication opens up quite a lot of opportunities in the business world, where one example is making decisions in the form of information quickly, precisely, and accurately. Thus, decision-making becomes an important fulcrum that we want to take a step. TOPSIS is a method based on the Multi Criteria Decision Making (MCDM) optimization tool. Where, TOPSIS is designed to solve the problem of choosing a middle way or achieving a solution. Where, TOPSIS reaches a decision based on the calculation of determining the distance for the best solution and the worst solution. (Khan & Maity, 2017) This research was conducted qualitatively, using the Personal Extreme Programming method. The advantage of Personal Extreme Programming, the modules created can be changed quickly. And Personal Extreme Programming does not require many programmers in the team. The results of this study are to provide a method or way to facilitate the entry of progress data that has been carried out by PT. Multi Bahtera Cemerlang. Then make it easier for decisions to be made. With the aim of increasing work efficiency in the company PT. Multi Bahtera Cemerlang. This research will produce a website in the form of web progress and web decision selection using the TOPSIS Algorithm. Then, the work process in the company PT. Multi Bahtera Cemerlang is faster. As well as applications that is made can be used easily.
Psychology of a forensic expert and forensic technologies
Authors: Alayeva G. T. , Rehson C. N.
Published: December 2024

The main role of forensic examination in the process of proof is to conduct scientific research of objects in order to solve problems significant for the purposes of legal proceedings and formalized in the conclusion of an expert recognized by the legislator as judicial evidence. The specificity of forensic expert activity distinguishes forensic expert proceedings from other legal proceedings, since it is associated with the establishment of evidentiary facts with the use of special knowledge. This seems to be a key element distinguishing forensic expertise. Techniques, tools, and methods of expert activity related to the receipt, processing, and evaluation of evidentiary information are also specific, the quality and reliability of which are significantly influenced by mental qualities and their characteristics. Therefore, the selection and placement of personnel in a forensic expert institution is a very difficult and urgent task and requires the preparation of profilograms to establish the suitability of the conc.