bluuebunny/crossref_metadata_2025 huggingface dataset:
Rohde’s Theory of Relationship between the Novel and Rhetoric and the Problem of Evaluating the Entire Corpus of Post-Classical Greek Literature
Authors: Kozić Ranko
Published: June 2023

The one hundred and fiftieth anniversary of the first publication of Rohde’s monograph on the Greek novel is drawing near, affording a welcome occasion to raise the big question as to what remains of it today, all the more so since the ancient novel, due to his classical work, has become a major area of research. The aforesaid monograph, considered to be one of the greatest scientific achievements of the nineteenth century, can be justifiably used as a litmus test for ascertaining how efficient the methods hitherto employed were or, in other words, whether we are entitled to speak of continuous progress in research or the opposite is true. Finally, the questions raised in the monograph will turn out to be more important than the results obtained by the author, in so far as the latter, based on his unfinished theses, proved to be very harmful to evaluating both the Greek novel and the entire corpus of post-classical Greek literature. In this paper we focus our attention on two major questions raised by the author such as division of the third type of narration in the rhetorical manuals of classical antiquity and the nature of rhetoric, as expressed in the writings of the major exponents of the Second Sophistic so as to be in a position to point to the way out of aporia, with the preliminary remark that we shall not be able to get a full picture of the Greek novel until the two remaining big questions posed by the author, namely the role played by both Tyche and women in the mentioned genre, are fully answered.
Сerebrolysin® influences in Sod- and sws-dependent neurodegenerative models of Drosophila melano­gaster
Authors:   Ivan Franko National University of Lviv, Matiytsiv Nataliya , Raspopina Anastasiia ,   Ivan Franko National University of Lviv, Dronska Khrystyna ,   Ivan Franko National University of Lviv, Novosiadla Zoryana ,   Ivan Franko National University of Lviv
Published: June 2023

Background. The incidence of human neurodegenerative disorders increases continuously as the human population ages. To date, these diseases remain incurable and require complex experimental approaches using tractable models to study the degeneration mechanisms and potential drug intervention regimens. In the current work, we assessed the impact of the neuroprotective drug Сerebrolysin on these neurodegenerative processes in Drosophila Sod1 and swiss cheese (sws) mutants. Materials and Methods. The experiments were conducted using a D. melano­gaster Sod1- and sws-dependent neurodegeneration model. Сerebrolysin (3 μL/mL) was added for larvae feeding. In order to evaluate Сerebrolysin influence, several tests were performed: locomotor activity assay, lifespan, size of brain tissue degeneration zones and sensitivity to prooxidant exposion. Results. Dietary supplementation with Сerebrolysin extended the lifespan of all flies under normal circumstances. The drug treatment also reduced the sensitivity of mutant flies to pro-oxidant effects. Moreover, treatment with Сerebrolysin partially diminished the size of degeneration zones in the brain tissue of sws1 mutant flies, without any notable effects on locomotor ability. Conclusions. The data obtained confirm the moderate neuroprotective and/or antioxidant action of Сerebrolysinagainst neurodegenerative processes under different genetic backgrounds.
Gas chromatographic-mass spectrometric characteristics of essential oils of plants of the genus Pycnanthemum (Lamiaceae) and peculiarities of their application in practice
Authors:   M. M. Gryshko National Botanical Garden, NAS of Ukraine, Kovtun-Vodyanytska Svitlana , Levchuk Iryna ,   Scientific and Research Center for Products Testing: State Enterprise “Ukrmetrteststandart”, Rakhmetov Dzhamal ,   M. M. Gryshko National Botanical Garden, NAS of Ukraine, Golubets Olga ,   Scientific and Research Center for Products Testing: State Enterprise “Ukrmetrteststandart”, Kostetska Kateryna ,   Uman National University of Horticulture, Levon Volodymyr ,   M. M. Gryshko National Botanical Garden, NAS of Ukraine
Published: June 2023

Background. Not all plants are capable of producing essential oil (EO). There are 3.000 different plant EOs described in the world, but only 10 % of them are widely used by humans. In particular, perfumery and the food industry use the largest amount of natural EOs – 30 % and 40 % of the world production, respectively. A thorough study of EOs, knowledge of their components in both chemical and pharmacological sense will facilitate the improvement of the quality of human life. The purpose of our experimental study was to determine the EO potential of four species of the genus Pycnanthemum Michx. (Lamiaceae): P. montanum Michx., P. muticum (Michx.) Pers., P. tenuifolium Schrad., P. verticillatum var. pilosum (Nutt.) Cooperr. introduced in the forest-steppe zone of Ukraine. The above plants are representatives of the flora of North America. Methods. The EOs were obtained in laboratory conditions by hydrodistillation using a Clevenger apparatus. The raw material of the plants – a blended mass of leaves, inflorescences and the herbaceous part of the stem was used in an air-dry state. Harvesting of raw materials was carried out during the flowering phase of plants. The EOs content is given in terms of an absolute dry weight. The identification of compounds and their amount in each EO was determined by the method of gas chromatography-mass spectrometry. Results. In the conditions of the forest-steppe of Ukraine, the introduced species of plants of the genus Pycnanthemum show a high level of EOs biosynthesis – 0.53–3.34 %. The dominant compounds common to the obtained essential oils are Pulegone, Isomenthone, and Isopinocamphone. The indicators of the content of pulegone exceed those of other compounds and reach 48.14–73.93 %. Pulegone is a controversial organic compound, since it exhibits a high biological activity and possesses pharmacological properties suitable for use in medical practice, but when cleaved, it forms toxic metabolites, in particular mentofuran. Conclusions. The obtained results indicate that plants of the genus Pycnanthemum, which are little known in Ukraine, have a high EO potential under the proposed growth conditions. Due to this, they are potential objects for use in domestic cultural phytocenoses. Considering the component composition of EOs with the dominant Pulegone, their consumption requires correct dosage.
Pathology of carotid triangle of the neck as one of the extra-respiratory causes of chronic cough (clinical case)
Authors: Vasyliuk N.V. , Dmytriv I.V.
Published: June 2023

One of the extra-respiratory causes of chronic hacking cough is a tumorous pathological process in the carotid triangle of the neck. A 41-year-old patient sought medical assistance for a hacking cough that worsened in the evening and had lasted for more than 8 weeks. After treatment prescribed by the primary care physician, the patient noticed a short­term improvement. However, shortly after discontinuing the therapy, the cough resumed and intensified. The patient was referred for a consultation with an otolaryngologist. During the examination, an elastic, condensed formation with somewhat limited mobility and a smooth surface measuring 2.5 × 3.0 cm was found in the area of the carotid triangle of the neck. Ultrasound examination of the soft tissues of the neck and ultrasound Dopplerography of the neck vessels were performed. An entity was detected that, based on all ultrasound characteristics, appears to be a carotid paraganglioma on both sides. The diagnostic conclusion was confirmed by the result of neck magnetic resonance imaging, which described carotid paragangliomas. After establishing the diagnosis of carotid chemodectoma in the neck, the patient was consulted by an oncologist and referred to a specialized department, where they underwent successful surgical treatment. Following the surgical intervention, the patient remained under the dispensary observation of an otolaryngologist and a vascular surgeon for the next 12 months. During this period, there were no complaints of cough recurrence. The cessation of the triggering factor in the afferent pathway of the neuroreflex arc of the cough reflex, achieved by removing the carotid paraganglioma, contributed to the disappearance of the cough — a symptom that had negatively impacted the patient's quality of life.The clinician should be highly vigilant if an initiated cough persists for several weeks or months and the patient demonstrates an excessively sensitive cough reflex. It is important to remember that chronic idiopathic cough can be a distinct clinical entity with an unidentified underlying pathology, and it can also contribute to the identification of a clinical pattern different from cough-associated diseases. In cases of persistent idiopathic cough that is unresponsive to treatment, the concept of distinct afferent pathways and an «anatomical diagnostic protocol» should be employed to determine the pathology and guide patient management.
Pollution indices assessment of metal concentrations in Karabuk soil samples
Authors: SEZGİN Naim , KINDA Saidou , TEMELLİ Uğur Emre , SEZGİN Nazan
Published: June 2023

Soil pollution refers to the contamination of soil by harmful substances that can have adverse effects on plant and animal life, it also negative affects the health-being of humans. The sources of soil pollution include industrial activities, agricultural practices, mining and transportation activities. The contaminants in soil can include heavy metals, pesticides, herbicides, fertilizers, petroleum products, and other chemicals. These contaminants can seep into the soil and accumulate over time, making the soil unsuitable for agriculture or other uses. Heavy metals are a significant concern in soil pollution due to their persistency and potential harm for living organisms. Therefore, it is essential to evaluate metal contamination in soil using ecological risk indices to protect human health. This assessment can help identify potential risks and enable effective management of contaminated sites. This study aimed to assess of the metal pollution levels, including Arsenic (As), Cobalt (Co), Chromium (Cr), Copper (Cu), Nickel (Ni), Lead (Pb), and Zinc (Zn), in soil samples from Karabuk using various ecological risk indices. These indices included the geo-accumulation index (Igeo), enrichment factor (EF), contamination factor (CF), contamination degree (Cd), pollution load index (PLI), and potential ecological risk (PERI). Furthermore, statistical techniques such as correlation and factor analysis were employed to determine the underlying sources responsible for these metals. Based on the results of the Cd, PLI, and PERI, it was found that the soil at T7 exhibited a very high degree of contamination, was moderately to highly polluted, and posed a moderate ecological risk, respectively. The results of the pollution indices suggest that the sources of pollution in the Karabuk soil samples are anthropogenic, meaning they are a result of human activities like industrial processes and improper waste disposal.
ВПЛИВ ОЛІМПІАД З ПРОГРАМУВАННЯ НА МОТИВАЦІЮ УЧНІВ ДО ВИВЧЕННЯ ІНФОРМАТИКИ
Authors: Носаченко Дар’я
Published: June 2023

Ця стаття досліджує вплив олімпіад з програмування на мотивацію учнів щодо вивчення інформатики та надає огляд їх впливу на інтерес та розуміння програмування. Акцентується на важливості підготовки молодих фахівців із комп'ютерними навичками, зокрема програмування, в контексті переходу до інформаційного суспільства. Зазначається значення шкільних олімпіад з програмування для виявлення та підготовки кандидатів на майбутню кар'єру в цій сфері.

Проблема мотивації учнів до вивчення програмування є актуальною в сучасному світі, де технології набувають все більшого значення. Кілька досліджень вказують на значний вплив олімпіад з програмування на мотивацію студентів до вивчення інформатики та їх вибір майбутньої кар'єри в галузі IT.

Додатково, стаття розглядає, як олімпіади з програмування можуть служити важливим інструментом для виявлення та підготовки молодих талантів у галузі програмування. Вона досліджує механізми, через які олімпіади з інформатики впливають на мотивацію учнів, що має особливе значення в контексті швидкого розвитку технологій та зростання попиту на фахівців у сфері IT. Олімпіади з програмування не тільки стимулюють інтерес до вивчення інформатики, але й допомагають учням розвивати навички вирішення проблем, логічного мислення та критичного аналізу.

Стаття також вказує на аспекти, які необхідно врахувати при підготовці до олімпіади чи конкурсу з програмування, щоб змагання мало позитивний вплив на мотивацію учнів, уникнувши стресу чи перенавантаження. До таких аспектів можуть відноситись стимулююча атмосфера, належна підготовка, наявність наставників та можливість для учасників розвивати свої здібності та отримувати визнання за свої досягнення.

Додатково, стаття розглядає важливість олімпіад з програмування як засобу для підвищення самооцінки та впевненості учнів у їхніх здібностях у сфері програмування. Успіхи на олімпіадах підтверджують їхній потенціал та стимулюють до подальшого розвитку у цій галузі.
Asuransi Menurut Pandangan Islam
Authors: wijaya suzanto , Kurniawan Rachmad Risqy
Published: June 2023

This research aims to examine a system that has just emerged in the past few years, this system is known as insurance, how Islam views it that way, we will examine in this study. In Islam, insurance has actually been practiced since the time of the Prophet Muhammad. According to some scholars, the forerunner of the concept of Islamic insurance is al-diyah `ala al-`āqilah. al-`āqilah was a custom of the Arab tribes long before Islam came. If a member of the tribe is killed by a member of another tribe, the victim's heir will be paid blood money (al-diyah) as compensation by the killer's next of kin. The killer's closest relative is known as al-`āqilah. After Islam came, the al-`āqilah system was ratified by Rasulullah SAW. become part of Islamic law. In fact, al-'aqilah is contained in the Medina Charter. In the following period, al-'aqilah or insurance continued to be carried out by the caliphs, especially during the time of Caliph Umar bin Khattab until now. Islamic insurance or sharia-based insurance has more social nuances than economic or profit-oriented nuances. Therefore, the aspect of helping each other is always used as the main basis for enforcing Islamic insurance practices. Islam views coverage as a social phenomenon formed on the basis of mutual assistance and humanity. Currently Islamic insurance has grown in various countries. This shows that Islamic insurance is quite attractive to people in various countries. The problem is, until now there are still many people, including some Muslims who do not understand Islamic insurance.
Model Kerjasama Niaga atau Dagang dalam Tinjauan Fiqih Kontemporer
Authors: Sitompul Oktapiani , Kurniawan Rachmad Risqy
Published: June 2023

Abstract: The The purpose of this research is to find out how the model of trade/trade cooperation is in a review of contemporary fiqh, especially regarding the collaboration model of resellers, dropshipping and MLM (multi level marketing). This research is a library research. The method used in this research is the legal istinbath method. The results of this research show that the emergence of trade/dangang cooperation models is currently making it very easy for people to start a business in doing business. There are even cooperation models that do not need to spend little capital. The models of trade/trade collaboration that are very popular today are resellers, dropshipping and MLM which are transactions that explain the characteristics of the goods or goods being sold, all of which are carried out by order and in these transactions the seller and buyer do not meet directly, and also the goods being traded do not exist because they can only be shown in the form of photos with the specifications and prices already stated in the photos. In a review of contemporary figh, the cooperation model still needs to emphasize the principle of responsibility
KEBIJAKAN PENDAPATAN DAN KEBIJAKAN BELANJA EKONOMI ISLAM
Authors: Amelia Kiki Rezky
Published: June 2023

Pandangan ekonomi Islam mengenai pendapatan negara akan selalu ber-kaitan dengan zakat, infak, sadaqah, waqaf, kharaj, ghanimah, khums dan jizyah. Negara memperoleh pendapatan dari instrumen tersebut. Adapun instrumen ter-sebut memiliki fungsi masing-masing. Dimana ke delapan instrumen atau sumber pendapatan negara menurut ekonomi Islam ini berasal dari beberapa sumber yang juga berbeda-beda.
PRAKTIK TRANSFUSI DARAH DITINJAU DARI PERSPEKTIF FIQIH KONTEMPORER
Authors: Hudzaifah  , Kurniawan Rachmad Risqy , harefa Primoadin
Published: June 2023

Transfusi darah termasuk permasalahan baru dalam wacana hukum Islam. Dalam konteks kajian Fiqh, darah termasuk benda najis secara dzatnya (lidzatihi). Dan tidak adanya hukum syar’i yang secara eksplisit membahas praktik transfusi darah. Hal ini menimbulkan kerancuan dalam kehidupan muslim. Risiko dan juga manfaat yang ditimbulkan dari praktik transfusi darah baik, dari pihak pendonor maupun penerima donor darah (resipien) perlu dipertimbangkan oleh keduanya. Tujuan dilakukanya ini adalah untuk menyelamatkan nyawa resipien baik, karena kecelakaan atau penyakit. Status hukum haram penggunaan darah menjadi wajib ketika dihadapkan dengan kebutuhan yang mendesak, pada saat transfusi darah menjadi satu-satunya jalan untuk menyelamatkan nyawa seseorang. Dalam hal ini didasarkan pada kaidah fiqhiyah asasiyah yang keempat yaitu: al-Ḍarar Yuzāl. (الضرر يزال) bahwa bahaya itu harus dihilangkan/dicegah. Jadi praktik donor darah merupakan hal yang harus dilakukan untuk menghindari kemudaratan yang lebih besar, misal akan kehilangan nyawa apabila tidak segera melakukan donor darah. Di samping itu juga diungkapkan dalam sebuah hadis yang diriwayatkan oleh Ibnu Majah dari Ibnu Abbas, لا ضرر ولا ضرر (tidak boleh memudaratkan dan tidak boleh dimudaratkan). Maka dari itu, dalam praktiknya transfusi darah perlu dipatuhi prosedur persyaratan dari program kesehatan kepada pihak pendonor dan resipien agar supaya tidak hanya menghilangkan bahaya resipien tapi juga terhindar dari membahayakan pihak pendonor.
TRABD2A is a differentially expressed gene in brain metastatic human breast cancer.
Authors: Mamoor Shahan
Published: June 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that TraB domain-containing 2A, encoded by TRABD2A, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. TRABD2A mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of TRABD2A in primary tumors was correlated with patient recurrence-free survival. Modulation of TRABD2A expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
FHIP2B is differentially expressed in central nervous system metastasis.
Authors: Mamoor Shahan
Published: June 2023

Metastasis to the brain occurs in a significant fraction of patients with solid tumors including breast cancer and metastatic melanoma (1-3). We mined published RNA-sequencing and microarray data (4, 5), comparing primary and brain metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the CNS. We found that FHF complex subunit HOOK-interacting protein 2B, encoded by FHIP2B, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. Study of microarray data (5) revealed conserved differential expression of FHIP2B in CNS metastasis in patients with metastatic melanoma. FHIP2B mRNA was present at decreased quantities in metastasis to the brain in humans with breast cancer. Expression of FHIP2B in primary tumors of the breast was correlated with patient recurrence-free survival. Modulation of FHIP2B expression may be relevant to the biology by which tumor cells metastasize to the brain in humans with solid tumors with propensity for the CNS including breast cancer and metastatic melanoma.
PRODUK -PRODUK BMT (BAITUL MAL WAT TAMWIL) DALAM (TABUNGAN, PEMBIAYAAN DAN JASA)
Authors: Irmawati
Published: June 2023

Essay tentang produk produk BMT dalam Tabungan pembiayaan dan jasa
Hukum bedah mayat
Authors: Kholid Muhammad Kholid
Published: June 2023

ABSTRAK The main problem in this title is how is the view of contemporary Islamic law regarding post-mortem examinations? 1) The purpose of this research is to find out the views of Contemporary Islamic law towards post-mortems, 2) To find out the factors that make it permissible to perform post-mortems in Islamic Law and in Medical Sciences.This type of research is library (Library Research), with the Syar'i approach and the formal Juridical approach. The data sources used are Contemporary fiqh books primary data sources, secondary data sources fiqh books, journals etc., and tertiary data sources, documents or Wikipedia. Data analysis is descriptive analysis.The results of the study, 1) Post-mortem surgery in the view of Contemporary Islamic Law is permissible on the grounds that it is seen based on the purpose of doing it, for the good and welfare of humans. 2) The reasons for the permissibility of post-mortem examination in Islamic law and in the world of medical science are the presence of valuable objects in the form of diamonds in the stomach of the corpse, for legal purposes in terms of investigations, for the benefit of medical science to save the fetus which is thought to be still alive in the womb. a mother who has died who most likely can still be saved.The implications of this research are expected to: 1) Law enforcers or the government should find a way out or other ways in terms of legal interests for the investigation process by dissecting someone's corpse, can use other methods such as using fingerprints or something else. 2) Then for the world of medical science in terms of practicing the knowledge of human organs for medical students, medical students can use replicas or statues that are exactly the same as humans and the organs in the human body.
The State of Open Science Practices in Psychometric Studies of Suicide: A Systematic Review
Authors: Flores-Kanter Pablo Ezequiel , Alvarado Jesús M.
Published: June 2023

Background: The adoption of open science practices (OSPs) is crucial for promoting transparency and robustness in research. We conducted a systematic review to assess the frequency and trends of OSPs in psychometric studies focusing on measures of suicidal thoughts and behavior. Methods: We analyzed publications from two international databases, examining the use of OSPs such as open access publication, preregistration, provision of open materials, and data sharing. The data were further analyzed based on publication year, first author's region of affiliation, and publication type (open access vs. restricted access). Results: Our findings indicate a lack of adherence to OSPs in psychometric studies of suicide. The majority of manuscripts were published under restricted access, and preregistrations were not utilized. The provision of open materials and data was rare, with limited access to instruments and analysis scripts. Open access versions (preprints/postprints) were scarce. Trends analysis showed inconsistent changes over the years, with regional variations in open access publication. Conclusions: The low adoption of OSPs in psychometric studies of suicide calls for urgent action. Researchers must prioritize the use of preregistration, publication of preprints/postprints, and providing access to materials and data. Embracing a culture of open science will enhance transparency, reproducibility, and the impact of research in suicide prevention efforts.
Hukum Arisan Menurut Syariah
Authors: Afkarina Robiah Husna , Kurniawan Rachmad Risqy
Published: June 2023

Abstract : This study aims to find out how the arisan law in Islamic sharia. The practice of muamalah that applies in society is basically something that has been agreed upon by the community itself, both in writing and in writing, but it does not rule out the possibility that the agreement is contrary to Islamic sharia. Not infrequently the scholars also differ in opinion in determining the laws in Islam, including the law regarding social gathering itself. Therefore it is important for us to know how the laws are in accordance with the provisions of Islamic law so that they can be applied in everyday life. The method used in this study is the istinbath fiqh method, by taking sources from the Qur’an and hadith then understanding and studying the laws and wisdom that can be drawn from these two sources.
Hukum Transplantasi Organ Tubuh
Authors: Ikhsan
Published: June 2023

Organ transplantation. However, the practice of organ transplants is still a matter of debate among scholars, whether it is allowed or not. This study discusses organ transplants in the Qur’an through the perspective of Maqasid interpretation (objectives of sharia). The method used is qualitative or library research with the Maqasid interpretation approach. The conclusions that can be drawn from this study are: First, a person is not allowed to give or sell their organs to others. It will be permissible only for urgent needs with some provisions: it is harmless to the donors, it is not the vital organs that affect his life, and there is no other medical efforts to cure it, except with a transplant. Second, the contribution that a Moslem can make in this organ transplantation is called hifz al-nafs (saving the soul).
Praktek Jual Beli Barang Bekas Dalam Tinjauan Fiqih
Authors: Rizky Muthia , Kurniawan Rachmad Risqy
Published: June 2023

My purpose was to do this because the problem of buying and selling usedgoods, honesty and concern of the owner of the goods (seller) for the condition of thegoods which is often the cause of fraud in the transactions made, namely the strongelements of gharar and tahgrir in the contract procession. Based on the results, it canbe concluded that buying and selling according to muamalah jurisprudence is invalidif the trade is not fulfilled in terms and conditions in buying and selling. To makeeverything honest and give khiyar rights to buyers is a solution to problems thatcommonly occur in used goods transactions. So this research is expected to providebenefits in the development of Islamic economics related to the law of buying andselling used goods, in the perspective of jurisprudence with the method of istinbathjurisprudence which is collecting information from hadith and the Quran.
Cryptocurrency dalam Tinjauan Ekonomi Islam
Authors: Shofiyah  , Kurniawan Rachmad Risqy
Published: June 2023

The development of the digital era is increasingly widespread where some of them do provide many conveniences, especially in terms of economic activity services. As an example of the emergence of cryptocurrencies or cryptocurrencies as digital currencies, these cryptocurrencies are designed or designed to be traded through one cryptographic technology or what is commonly called a block chain which is decentralized in nature to carry out a trade or transfer from one party to another. In such a way the perpetrators are anonymous and there is no law governing and being responsible for this. Even though it provides a number of advantages for its users, the existence of cryptocurrency in Indonesia is still experiencing debate both in terms of regulation and legality, especially from the perspective of Islamic law for its use.This research was conducted to review cryptocurrencies which are widely used in society such as in buying and selling transactions, investments, mining, trading, and other things both from the definition, types, and legal arguments from an Islamic legal perspective. This research is a library research (library research) qualitative in nature. The data analysis technique in this study is descriptive-analytical with a normative juridical approach to Islamic law. Based on a number of references cited in this study, it is known that investing in cryptocurrency has a very high risk because its value can rise or fall drastically and is unpredictable. In addition, cryptocurrencies are also considered to be able to maintain the value of one's wealth far better than cash, even gold. Then the practice of buying and selling digital currency (cryptocurrency) is quite interesting where it offers quite high flexibility and can be done anytime and anywhere around the world. On the other hand, the jury of contemporary scholars considers that any form of cryptocurrency, be it bitcoin, aternity, or other coins cannot be called money, thus giving rise to various controversies about the legal use of these cryptocurrencies.
Bisnis Rokok dalam Tinjauan Fiqh
Authors: Ristianti Dinni , Kurniawan Rachmad Risqy
Published: June 2023

This research is motivated by cases that occurred in modern times which did not exist at the time of the Prophet SAW, namely regarding the law of the cigarette business and anything related to the law of smoking. This research uses the maudhu'i method and takes from the Al-Qur'an and the hadith as well as the opinions of the scholars. The results of the study show that the legal business of cigarettes is haram because smoking has many harmful effects.
Leptin is differentially expressed in brain metastatic human breast cancer.
Authors: Mamoor Shahan
Published: June 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that leptin, encoded by LEP, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. LEP mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of LEP in primary tumors was not correlated with patient survival outcomes. Modulation of LEP expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Jual Beli Online Dalam Islam
Authors: Dadan Asep , Kurniawan Rachmad Risqy
Published: June 2023

Tujuan penelitian ini adalah untuk mengkaji lebih mendalam mengenai jual beli online yang didasari atau diperbolehkan di dalam islam. Pada dasarnya jual beli online ini, tidak ada sejak zaman Rasulullah shallallahu alaihi wasallam karena pada zaman nabi jual beli dilakukan secara langsung dengan terpenuhinya rukun jual beli. Sebagaimana yang kita telah ketahui bahwa pada zaman sekarang khususnya di era generasi z ini, ada banyak sekali muncul jual beli yang memang tidak ada pada zaman nabi seperti, online shop di tiktok shop, shopee, Lazada, akulaku, marketplace, Bukalapak, dan lain-lain. Jual beli online merupakan jual beli yang bentuk transaksinya secara tidak langsung (online). Hasil dalam penelitian ini Islam mengajarkan dan melakukan jual beli online yang sah tanpa didasari dengan riba, ketidakadilan, monopoli, dan penipuan. Nabi menyadari bahwa jual beli online ketika di dalamnya terdapat (antaradhin) suka sama suka dan melalui online tidak dibolehkan jual beli yang tidak dijelaskan menurut syariah.
PRAKTEK BISNIS HARTA WARISAN DI INDONESIA DALAM PERSPEKTIF FIQIH
Authors: Sinarti Reni , Kurniawan Rachmad Risqy
Published: June 2023

My purpose was to do this research to find out how Islamic law is about transactions or transactions of property according to the qur 'an and its interpretation and hadith. The study conducted library research using the maudhu'i (graphic) interpretation method by using several references to the book of tafsir al-munir and fiqih muamalah. These studies indicate that many of the beneficiaries have traded expertly to both partial and family. Such things as land land, ancestral homes, plantation assets, and even more unsuitable to the Friday, there are heirs who have withdrawn the land that the parents had previously acquired for resale and many other assets. Does Islam therefore have within Islam an heir to sell off its parents' immaterial assets? In Islam it has some opinions that some things are allowed to be sold as long as counted later when dividing the inheritance and some things are not allowed: waqaf is withdrawn into the inheritance or even sold.
USE OF READING CORNER AND WALL MAGAZINE IN LITERACY ACTIVITIES OF CLASS IV STUDENTS OF SD NEGERI 1 BAYEMHARJO
Authors: Kinasih Ayu Ragil
Published: June 2023

This article aims to examine the use of reading corners and bulletin boards in literacy activities.
A Novel Approach to Model Cumulative Stress: Area Under the s-factor Curve
Authors: Mann Frank D. , Cuevas Adolfo , Clouston Sean , Freilich Colin , Krizan Zlatan , Zuber Sascha , Wänström Linda , Muniz-Terrera Graciela , O’Keefe Patrick , Voll Stacey , Hofer Scott Michael , Rodgers Joseph Lee , Krueger Robert
Published: June 2023

Objective: Using a large longitudinal sample of adults from the Midlife in the United States (MIDUS) study, the present study extended a recently developed hierarchical model to determine how best to longitudinally model cumulative stress, and to determine whether the rate of change in stress or the level of cumulative stress over time are stronger predictors of health outcomes. Method: We used factor analysis to estimate a stress-factor score and then, to operationalize the accumulation of stress we examined four approaches to aggregating information about repeated exposures to multiple stressors. The predictive validity of these approaches was then assessed in relation to different health outcomes. Results: The prediction of chronic conditions, body mass index, difficulty with activities of daily living, executive function, and working memory later in life was strongest when cumulative stress was modeled using area under the curve with respect to ground (AUCG), compared to composite scores that have traditionally been used in studies of cumulative stress, as well as linear rates of change. Conclusions: Similar to endogenous, biological markers of stress reactivity, AUCG for individual trajectories of self-reported stressors shows promise as a data reduction technique to model cumulative stress in longitudinal studies. Overall, our results indicate that considering different quantitative models of cumulative stress is critical to understanding the sequelae of stress exposures from midlife to late adulthood.
The inferior fronto-occipital fasciculus correlates with early precursors of mathematics and reading before the start of formal schooling
Authors: Vandecruys Floor , Vandermosten Maaike , De Smedt Bert
Published: June 2023

Diffusion-weighted imaging studies in preschoolers have almost exclusively been done in the field of reading. As a result, virtually nothing is known about white matter tracts associated with individual differences in mathematics at this age. Studying the preschoolers’ brain is crucial because it allows us to identify individual differences in brain anatomy without influences of formal mathematics and reading instruction. To fill this gap, we investigated for the first time before the start of formal school entry the associations between white matter tracts and precursors of mathematics and reading simultaneously. We also investigated whether associations were specific to mathematics and to reading, or not. We focused on four bilateral white matter tracts (arcuate fasciculus (direct, anterior), inferior fronto-occipital fasciculus, inferior longitudinal fasciculus) that have been previously correlated with mathematical performance in older children and with reading performance in children of a similar age as ours. Participants were 56 5-year-old children (Mage = 67 months; SD = 1.8), none of which received formal instruction. Our results showed an association between the bilateral inferior fronto-occipital fasciculus and precursors of mathematics (numerical ordering, numeral knowledge) and reading (phonological awareness, letter knowledge). Follow-up regression analyses revealed that the associations found with the inferior fronto-occipital fasciculus were neither specific to mathematics nor specific to reading. These findings suggest that, already before the start of formal schooling, the inferior fronto-occipital fasciculus might be related to the neural overlap of mathematics and reading. This overlap potentially reflects one of their many shared mechanisms, such as the reliance on phonological codes or the processing of visual symbols, and these should be exploited in future studies.
Algorithm aversion or appreciation? Three randomized field trials of personalized risk-communication nudges to encourage flu vaccination
Authors: Rosenbaum Gail , Goren Amir , Shermohammed Maheen , Wolk Donna M. , Tice Ann Marie , Doyle Joseph , Meyer Michelle N. , Chabris Christopher F.
Published: June 2023

Artificial intelligence (AI) is increasingly used in healthcare to identify high-risk patients needing intervention. Communicating AI-derived personalized risk information is an untested health behavior change intervention; laboratory studies are mixed regarding patient favorability toward AI use. We ran a field test comprising three large-scale preregistered randomized controlled trials with over 90,000 unique patients. Nudge messages encouraged influenza vaccination in patients identified by a previously validated machine-learning algorithm to be at high risk for flu and flu-related complications. For patients informed they were at high risk, vaccination was 1.1–1.4 percentage points (3.3%–5.4%) higher vs. those not told they were at high risk, and 1.7–3.5 percentage points (3.3%–14.7%) higher vs. non-messaged patients. Therefore, informing patients of personalized risk may effectively encourage their acting on AI-derived information. Vaccination was similar across message arms that did vs. did not disclose the “algorithm,” indicating patients are neither averse to nor appreciative of recommendations that cite an algorithm.
AGRARIAN REFORM IN BRAZIL: PROMINENCE OF THE MST IN THE MITIGATION OF SOCIAL DISPARITIES IN THE COUNTRYSIDE
Authors: de Oliveira Andrade Emanuel , da Silva Breno Nery
Published: June 2023

The present study aims to list the significance of agrarian reform in the current Brazilian conjuncture, in view of the plural perspective that this system presupposes linked to social movements that fight for the right to land. Among these movements, the MST emerges as a fundamental piece that paves the way for the dissolution of social injustices in the countryside, that is, this group assumes the prerogative of obtaining and dividing lands that do not fulfill the social function of the soil, thus aiming at the conquest and redistribution. of these areas that, for a long time, remain with debts speculating only the financial value when passing the years against the members of this and other acronyms that fight for the condition of producing, commercializing and subsisting through planting. In addition, it should be noted that the MST has a socio-affirmative agenda, in which, women, black people and people of different sexualities assume positions of leadership, dialogue and prestige, that is, the movement is plural, progressive and tends to break with patriarchal patterns still present in contemporaneity.
Districting Without Parties: How City Council Maps Increase Minority Representation
Authors: Hankinson Michael , Magazinnik Asya
Published: June 2023

District elections have long been considered a tool for promoting minority representation in local government. But surprisingly little is understood about how electoral maps themselves shape political outcomes. We collect over one hundred new districting plans from cities across California that converted from at-large to district elections in the wake of the California Voting Rights Act of 2001. Applying a state-of-the-art automated redistricting simulator, we find that most of these cities could not feasibly produce a plan with even one Latino-majority seat, though those that could generally tried to maximize this quantity. We introduce alternative metrics of descriptive representation that are tailored to a city's political dynamics and risk tolerance around securing at least one Latino seat. Contrary to intuitions from partisan districting, we see no conflict between the goals of guaranteeing minimal representation and maximizing seats overall; rather, we find that concentrating Latino voters within districts often achieves both goals and at no expense for Latinos' substantive representation.
Application of the Team-Assisted Individualization Learning Model to Improve Students' Critical Thinking Skills in Mathematics in Fourth Grade Elementary Schools
Authors: Andari Ade Mustika , Andriani Melly , Habibi Mhmd , Risna Wati Risna Wati
Published: June 2023

This study describes the improvement of the Team Assisted Individualization learning model in the fourth grade of SD Negeri 028 Kubang Jaya in improving students' mathematical critical thinking skills. This research is classroom action research, which consists of two cycles. The subjects in this study were one teacher and fifteen fourth-grade students at 028 Kubang Jaya Elementary School. Data collection was carried out through observation, testing, and documentation, with qualitative data analysis using percentages. Based on the research results and data analysis, it was shown that before the action, 11 (73%) students were in the less critical category, and 3 (20%) students were in the critical category. 6.6% of students are in the quite critical category. Team-assisted, individualized learning applies remedial actions. After taking corrective action with the team-assisted individualization learning model. Then corrective action is taken with the team-assisted individualization learning model. In cycle I, students' critical thinking skills increased; 6 students, or 40%, were in the critical category, and 9 students, or 60%, were in the moderately critical category. Furthermore, in cycle II, the ability to think critically has increased: 8 students, or 53%, are in the very critical category, 4 students, or 26%, are in the moderately critical category, and 3 students, or 20%, are in the critical category. In cycle II, students' critical thinking skills have achieved the target success of the action set. Thus, it can be concluded that the application of the team-assisted individualization learning model can improve students' critical thinking skills in fourth-grade mathematics at Public Elementary School 028 Kubang Jaya.
The Practicality and Effectiveness of the Chemical Snakes and Ladders Game on Acid-Base Material on the Learning Outcomes of Class XI SMA/MA Students
Authors: Lantusia Marina , Iswendi Iswendi
Published: June 2023

This research was motivated by the availability of the chemical ladder snake game as a medium for learning acid-base material developed by Amalia Putri Lubis & Iswendi. It is valid but not tested for practicality and effectiveness. This study aims to determine the suitability and effectiveness of the chemical snakes and ladders game. This type of research is a continuation of development research with a Pretest-Posttest Control Group Design and is a 4-D model development. The research population is class XI MIPA students of SMAN 1 Ranah Batahan. Samples takeusing by Simple Random Sampling technique. The research instruments were useful questionnaires and learning achievement tests. The data analysis technique is the practicality percentage technique and the N-Gain test and t-test. The results of the data analysis of practicality are, at a convenient level, for effectiveness the results of data analysis show pretty effective. This is evidenced by the N-Gain percentage of the experimental class of 66% at a somewhatadequate level and the control class of 47% at a less practical level, and supported by hypothesis testing with the t-test, namely tcount (2.6686)> table (2.0106) at the real level α = 0.05 with dk = 48 and chance t0.95.
Description of Students' Learning and Innovation Skills in Global Warming Learning Class X SMA Penggerak
Authors: Anggraini Dwi Shinta , Fitriza Zonalia
Published: June 2023

The 21st century is known as the century of knowledge that experiences rapid changes, to deal with it a skill is needed. One of the 21st century skills is learning and innovation skills or known as 4Cs, namely Communication, Collaboration, Critical Thinking and Problem-Solving, Creativity and Innovation. Students' 4Cs skills are highly demanded during the learning process, so it is important to assess students' 4Cs skills. Global warming is one of the chemistry subject matter in the penggerak school curriculum. This type of research is descriptive research with a qualitative approach. The study aims to describe the 4C skills of students in class XE7 SMA Negeri 2 padang with a total of 30 students. This study used an observation sheet. The results showed that overall the communication skills of students in class XE7 SMA Negeri 2 Padang were on average classified in the incompetent category (55% of students), students' collaboration skills were classified in the competent category (42% of students), students' critical thinking and problem-solving skills were classified in the incompetent category (40% of students), and creativity and innovation skills were classified in the incompetent category (88% of students).
Mathematics Literacy of Grade 4 Elementary School Students in Solving HOTS Type Mathematics Problems
Authors: Aulia Hantika , Habibi Muhammad , Risnawati Risnawati
Published: June 2023

The purpose of this study was to determine the level of mathematical literacy possessed by students related to the completion of HOTS-type questions found in FPB and KPK content. Written exams, interviews, and documentation are the three data collection methods used in this study. The participants in this study were three children at Grade 4 Elementary School 001 Air Tiris. The level of the students' mathematical abilities ranged from high, medium, and low. The ability to solve problems and frame problems, the ability to apply mathematics, and the ability to communicate are the three components of mathematical literacy skills used in this study. The results of the study show that the use of HOTS-type math problems for learning mathematics improves problem solving, application of mathematics, and communication. According to the introduction to the section, There are still wrong answers, so each student's mathematical literacy is unique. Students have demonstrated the ability to understand and construct problems, particularly in the areas of problem solving and problem formulation. Students' conceptual and procedural problem-solving abilities in mathematics are limited, and this limits their ability to adequately apply mathematics to real-world situations. In terms of communicating, not all students are able to write responses in a logical way. In addition, they do not write down clear problem-solving strategies and do not include conclusions.