bluuebunny/crossref_metadata_2025 huggingface dataset:
Discovery of Channa StriataExtracts as Regenerative Medicine in Promoting Wound Healing and Scarless Skin Regeneration
Authors: Kwan Soon Hong , Ismail Mohd Nazri
Published: June 2020

Channa striata (also known as Channa striatus) is an air-breathing freshwater snakehead
fish that is well known in the Asian region for its medicinal properties, particularly in wound
healing. It is recognised as a traditional medicine (TM), which can be served as alternative treatment
method. With the advancement of technology, researchers have made a lot of progress in
characterising the biomolecules of this fish. Various types of bioactive molecules have been
identified in the fish, and their therapeutic effects are being studied. The C. striata have exhibited
antibacterial, antinociceptive and effective wound recovery property through various pharmacology
assays. It has been regarded as a source of traditional medicine that could complement modern
medicine in promoting human health. The applications of C. striata extracts by practitioners in
treating different illnesses are discussed. Besides, the approaches towards scarless wound in future
applications involving the snakehead fish are also highlighted. Challenges and solutions to develop
an aquatic-derived drug were also covered. The Channa striata extract as a natural product has
shown great prospects for wound healing enhancement. Many biomolecules associated with
antibacterial and antinociceptive properties, which are crucial for healthy wound recovery were
identified in the species. Significant advances and researches in the region have successfully led to a
better understanding of the species, which provide a promising future for drug development.
An Effective Congestion Control Algorithm based on Traffic Assignment and Reassignment in Wireless Sensor Network
Authors: Wang Chao
Published: June 2020

Background:

It is important to improve the quality of service by using congestion detection
technology to find the potential congestion as early as possible in wireless sensor network.

Methods:

So an improved congestion control scheme based on traffic assignment and reassignment
algorithm is proposed for congestion avoidance, detection and mitigation. The congestion area of
the network is detected by predicting and setting threshold. When the congestion occurs, sensor
nodes can be recovery quickly from congestion by adopting reasonable method of traffic reassignment.
And the method can ensure the data in the congestion areas can be transferred to noncongestion
areas as soon as possible.

Results:

The simulation results indicate that the proposed scheme can reduce the number of loss
packets, improve the throughput, stabilize the average transmission rate of source node and reduce
the end-to-end delay.

Conclusion:

: So the proposed scheme can enhance the overall performance of the network. Keywords:
wireless sensor network; congestion control; congestion detection; congestion mitigation;
traffic assignment; traffic reassignment.
Análise da Lei de Menzerath no Português Brasileiro
Authors: Araujo Leonardo Carneiro , Benevides Aline , Pereira Marcos
Published: June 2020

Sob a ótica da Linguística Quantitativa, este trabalho revisita a Lei de Menzerath, aplicando-a aos dados do português brasileiro, a partir das seguintes unidades de análise: palavras, sílabas e fonemas. Os dados foram extraídos do Corpus ABG. Análises estatísticas foram realizadas nos modelos propostos, as quais demonstraram uma relação de decrescimento entre o comprimento médio das palavras (em sílabas) e o comprimento médio das sílabas (em fonemas); resultados esses que corroboram a Lei de Menzerath. Alémdisso, constatou-se, de maneira geral, que melhores medições ou a existência de variáveis não consideradas no modelo poderão ser utilizadas para melhorá-lo.
Reescrita sentencial baseada em traços de personalidade
Authors: Stavracas Neto Georges Basile , Paraboni Ivandré
Published: June 2020

Sistemas de Geração de Língua Natural (GLN) são centrais para o desenvolvimento de comunicação humano-computador realista e psicologicamente plausível que não recorra ao uso de texto fixo ou predefinido, fazendo uso de uma ampla gama de estratégias para modelar alguma forma de variação estilística. Entre estas estratégias, o uso de modelos computacionais da personalidade humana emergiu como uma alternativa popular na área. Neste contexto, o presente trabalho apresenta um modelo de GLN do tipo texto-para-texto (ou reescrita sentencial) para o português que leva em conta, além da sentença a ser reescrita, informações sobre a personalidade de um locutor-alvo de interesse. Mais especificamente, o modelo transforma a sentença de entrada em outra na qual certas formas lexicais são substituídas por termos mais adequados ao tipo de personalidade-alvo fornecido. Resultados sugerem que as sentenças geradas com base em personalidade são mais próximas das que seriam produzidas por um locutor humano com as características de personalidade fornecidas do que seria possível sem acesso a essa informação, e abrem assim caminho para futuros estudos de geração de língua natural personalizada em português.
Arte pública urbana e comunicação turística
Authors: Andrade Pedro
Published: June 2020

O presente texto, por um lado, visa descortinar alguns dos debates recentes sobre a arte

pública urbana, e as suas práticas mais criativas. Nesta perspetiva, apresenta-se um estudo de

caso ilustrativo sobre o Iminente Festival enquanto interculturalidade imanente à arte pública.

Em seguida, discute-se a e-arte pública, ou seja, a arte pública que é produzida e partilhada no

ciberespaço e no cibertempo. Depois, estas iniciativas artísticas são confrontadas com controvérsias,

clássicas e atuais, acerca das culturas móveis como o turismo e, em especial, o processo

da comunicação turística. Novas epistemologias e metodologias sociológicas encontram-se

igualmente abordadas, e exemplificadas com a Sociologia Artística, a Hibridologia e a Banda

Desenhada Sociológica. Finalmente, um breve glossário busca sintetizar e definir alguns conceitos

sociológicos que circunscrevem processos sociais centrais, subjacentes à articulação e

hibridação entre a arte pública urbana e a comunicação turística.
Mover o olhar sobre circulações da arte e receção
Authors: Conde Idalina
Published: June 2020

Contribuição sobre culturas móveis, este texto aborda circulações físicas, visuais e imaginárias

da arte com passagem do museu e de exposições para o espaço público. Assim, arte de

indoors para outdoors com mutações que atravessam os quadros da visitabilidade, semiologia,

mediações e modos de perceção versus receção. Algumas recriações de Las Meninas de Diego

Velázquez e Zodiac Heads/Circle of Animals de Ai Weiwei são exemplos em contraponto que ilustram

a problemática da mobilidade, com metamorfoses e itinerâncias. Mover o olhar significa

seguir essas viagens como um salto interpretativo sobre contextos e relações com a arte.
Method of discussion and learning styles towards student’s critical thinking ability
Authors: Fuad A. Jauhar
Published: June 2020

Active learning with student centering can improve critical thinking skills. Debates and discussions encourage active learning. Both are oriented toward critical thinking ability, in addition to the learning styles also make an impact on critical thinking ability. This paper aims to answer whether there are (1) differences in students critical thinking ability in the debate class and discussion class, (2) differences in critical thinking ability of students who have divergent learning styles and convergent learning style, and (3) interaction between learning method and learning style to critical thinking ability? This study uses a pseudo experimental design. Subjects in this study are students semester II. Analytical technique using Anova. The results of this study conclude: (1) there is no difference in critical thinking ability between debating class and discussion class, (2) there is difference of critical thinking ability between convergent learning style and divergent learning style, convergent learning style is better than divergent learning style, and (3) there is interaction between learning method and learning style to critical thinking ability which means that the influence of learning method on critical thinking ability is influenced by learning style.
Pengimplementasian e-modul etnokonstruktivisme terhadap motivasi belajar peserta didik Kelas V sekolah dasar
Authors: Kurniawati Eka Feri
Published: June 2020

Penelitian ini bertujuan untuk mengembangkan produk bahan ajar berupa modul pembelajaran. Modul pembelajaran dibuat dalam bentuk eletronik modul atau e-modul dengan dengan berbasis etnokonstruktivisme. Penelitian  ini megadopsi model dari Branch yaitu ADDIE (Analyze, Design, Development, Implementation, dan Evaluation). Subjek dari penelitian ini adalah peserta didik kelas V SD Negeri No.80/I Muara Bulian yang berjumlah 28 orang. Hasil dari penelitian ini digunakan untuk melihat kelayakan dan motivasi peserta didik terhadap e-modul yang dikembangkan dan untuk mengetahui  motivasi  peserta didik. Hasil data yang diperoleh menunjukkan dari 28 responden yang mengisi angket motivasi menunjukkan bahwa frekuensi terbesar sebanyak 19 dengan presentase 67.8% termasuk ke dalam kategori Baik. Hasil dari penelitian ini menunjukkan bahwa e-modul berbasis etnokonstruktivisme layak untuk dikembangkan dan digunakan sebagai tambahan bahan ajar guna mendukung kegiatan pembelajaran untuk membantu menumbuhkan motivasi belajar peserta didik.
Upaya meningkatkan minat belajar pelajaran seni budaya melalui model discovery learning dengan media puzzle
Authors: Kasmiatun Kasmiatun
Published: June 2020

Best practice ini bertujuan untuk meningkatkan minat belajar siswa pelajaran seni budaya terhadap materi ragam hias pada bahan alam (kayu) menggunakan model discovery learning dengan media puzzle. Karya tulis ini menceritakan pengalaman terbaik guru dalam menyelesaikan sebuah permasalahan pembelajaran di kelasnya. Hasil analisis data nilai minat belajar siswa menunjukkan adanya peningkatan minat belajar siswa yaitu nilai persentase klasikal minat belajar siswa 89% dengan kategori 94% tinggi yang berdampak pada nilai hasil belajar siswa sehingga mengalami peningkatan dengan nilai rata-rata kelas 92% dan ketuntasan klasikal 87.5%. Kesimpulan best practice ini adalah bahwa penggunaan model discovery learning dengan media  puzzle dapat meningkatkan minat belajar siswa pelajaran seni budaya terhadap materi ragam hias pada bahan alam (kayu) di kelas VII A SMP Negeri 1 Teluk Bayur.
Pemilihan Media Pembelajaran Terbaik Sebagai Sarana Pembelajaran yang Efektif Menggunakan Metode SAW
Authors: Trisnawati Trisnawati , Puastuti Dwi , Sholeha Lutvia
Published: June 2020

Dalam menentukan media pembelajaran bagi anak PAUD dan TK,  guru harus memiliki kreativitas yang tinggi dan  wawasan yang luas. Jumlah PAUD dan TK yang ada di kecamatan pringsewu ada 52 dan penelitian dilakukan di salah satu PAUD yang ada di kecatamatan pringsewu yaitu PAUD AL HADDII. Sistem pendukung keputusan bisa menjadi cara alternatife yang interaktif guna membantu mengambil keputusan melalui data dan informasi. Metode Simple Addtive Weighting (SAW) dapat membantu dalam pengambilan keputusan suatu  masalah dalam perhitungan.akan tetapi perhitungan dengan menggunakan metode Simple additive weighting ini hanya akan menghasialkan nilai terbesar yang akan terpilih sebagai alternatif terbaik. Perhitungan akan sesuai dengan metode ini apabila alternatif yang terpilih memenuhi kriteria yang telah ditentukan. Dengan demikian melakukan perankingan terhadap bobot nilai yang diambil dari criteria C1audio,C2 Visual,C3 audio visual, C4lingkungan, C5 permainan, C6 seni rupa. Dari hasil tiga alternative yang diuji didapatkan nilai dari hasil A1 = 67, A2 = 91.5, A3= 92, dengan nilai terbesar ada pada A3 sehingga A3 yaitu kurikulum 2013. Media pembelajaran nya adalah music, gambar, dongeng, keluarga, membangun menara, dan kolase.  dapat dikatakan sebagai media pembelajaran Terbaik. Manfaat yang ingin dicapai dari penelitian adalah untuk meningkatkan kulitas hasil belajar anak,proses pembelajaran menjadi lebih jelas dan menarik , dan dalam penyampaian materi pembelajaran dapat disamaratakan.
Analysis of the links between endothelium-dependent vasodilation indicators and the levels of high-sensitivity C-reactive protein and fractalkine/CX3CL1 in patients with acute coronary syndrome
Authors: Polunina E. A. , Kuzmichev K. Yu. , Voronina L. P. , Polunina O. S. , Sevostyanova I. V.
Published: June 2020

Objective: to study and analyze the links between endothelium-dependent vasodilation (EDV) indicators and the levels of fractalkine (FN/CX3CL1) and high sensitivity C-reactive protein (hs-CRP) in patients with acute coronary syndrome (ACS).

Materials and methods: among the examined individuals with ACS, 63 patients had acute myocardial infarction (MI); 41 patients had unstable angina (UA), represented by first – time angina in 15 people and 26 people had progressive angina. Control group included 20 healthy control individuals. Pharmacological test with 5% acetylcholine (AcH) was used to assess the functional state of the vascular endothelium. Enzyme-linked immunosorbent assay was used to determine the levels of FN/CX3CL1 and hs-CRP.

Results: all the examined patients with ACS showed statistically significant changes in EDV indicators compared to the control group, as well as an increase in the level of FN/CX3CL1 and hs-CRP. The most pronounced changes of the values of EDV indicators and the levels of FN/CX3CL1 and hs-CRP, from the examined patients, were detected among patients with acute MI. Th e presence of correlations between the studied indicators was revealed. Th e strength of the identified links was greater among patients with acute MI, compared to patients with UA. Th e strength of the links found in patients with both UA and acute MI was greater between EDV indicators and FN/CX3CL1 levels, than between EDV indicators and hs-CRP levels.

Conclusions:all the examined patients with ACS had the EDV disorders associated with the severity of systemic infl ammation. In the group of patients with acute MI, the severity of EDV disorders was greater than in patients with UA, which was apparently due to the infl uence of the resorption-necrotic syndrome, which potentiates increased systemic infl ammation and damage to the endothelium of microvessels with EDV disorders, which was confirmed by the results of correlation analysis. A positive link was found between the levels of FN/CX3CL1 hs-CRP.
On the histological structure of Kaposi’s sarcoma
Authors: Derizhanova I. S. , Balyshev O. O.
Published: June 2020

Objective: to study the histological structure of various types of Kaposi’s sarcoma and the morphogenetic potentials of vascular cells in the tumor growth.

Materials and methods: results of the histological examination of Kaposi’s sarcoma from 5 patients have been analyzed: biopsies of the skin and subcutaneous tissue from 3 HIV-infected patients (2 men and 1 woman) and 1 man, a participator of the liquidation (dosimetrist) of the consequences of the Chernobyl accident in 1986. The tumor nodes of the Kaposi’s sarcoma of the stomach, lymphatic mesenteric node and dura mater of a 41-year-old woman who had died aft er allogeneic kidney transplantation due to glomerulonephritis were also examined while the skin was intact. Histological preparations were stained with hematoxylin and eosin, picrofuchsin according to Van Gieson, alcian blue and impregnated with silver according to Bilshovsky.

Results: it was confirmed that Kaposi’s sarcoma is the part of a multicentrally occurring viral lesion of the skin, subcutaneous tissue and internal organs caused by herpes infections of the 8th type on the background of immunosuppression. The entire process of tumor formation includes, besides the tumor growth, pre-tumor conditions (viral infection, chronic inflammation), and pre-tumor processes (intravascular neoplasia of low and high degree), which determining the diversity of the histological structure, clinical course, outcomes of neoplasms and complicates the correct diagnosis. The morphogenetic potentialities of endothelial and perithelial cells which make various variants of angiomatous structures, and also form spindle cell, myofibroblastic and fi broblastic components, are also important.

Conclusions: the fifth, not yet described in the literature, variant of Kaposi’s sarcoma is highlighted - radiation, due to exposure of radiation energy.
Features of the formation of the professional role of a doctor in Russian and foreign practice
Authors: Ajvazyan S. G. , Ellanskiy Y. G. , Mirzoyan E. S. , Ilyukhun R. G. , Komarevtsev A. A.
Published: June 2020

The article deals with changes in sociological models of the professional role of a physician in a market economy. The article analyzes the importance of marketing in healthcare and models of providing medical services in Russian and foreign healthcare systems. Based on the accumulated literature data, it is possible to trace the dynamics of the relationship between the patient and the healthcare system towards the formation of consumer ideology and the importance of sociological research of the status and role parameters of the physician in order to improve the eff ectiveness and quality of provided medical care.
About the characteristics of «internal» and «external» epidemiological risks in the territory Rostov region
Authors: Kononenko A. A. , Vodyanitskaya S. S.
Published: June 2020

Objective: to identify some «internal» and «external» risks that are signifi cant for the Rostov region and calculate their quantitative characteristics.

Materials and methods: materials for «internal» risks in the administrative territories of the Rostov region served materials FBUZ «Center of hygiene and epidemiology in the Rostov region» on the incidence of Crimean hemorrhagic fever (KGL) and West Nile (LSN) during the period 2004 – 2017 as a whole across the Rostov region and the slit regions, the data of the regional law «About administrative-territorial structure of Rostov region», the Results of the national census. To determine the «internal» risks, we used the guidelines developed by us «Methodology for assessing the territory of the subject of the Russian Federation on the integral indicator of population morbidity with arbovirus infections», approved by Th e decision of the Academic Council of the Rostov-on-Don anti-plague Institute of Rospotrebnadzor and approved by the Director.

Results: based on the results of the ranking of the territory of the Rostov region on the incidence of KGL and LDL, the degree of epidemiological risk was assessed and «risk territories» were identifi ed for these nosologies, which can serve as a basis for risk management — making scientifi cally based management decisions. To calculate the magnitude of the «external» risk and further spread of the disease, you can use various methods to assess the probability of adverse development of the epidemiological situation under the infl uence of various risk factors. Epidemiological risk can also be characterized by multiplying the individual risk by the population exposed to risk factors.

Conclusions: identifi cation and calculation of risk levels depending on risk factors will help determine the scope of management decisions, and the specifi cation of risk factors will allow you to develop specifi c measures to reduce risk.
The role of cytokines in bone remodeling and the pathogenesis of postmenopausal osteoporosis
Authors: Ignatenko G. A. , Nemsadze I. G. , Mirovich E. D. , Churilov A. V. , Maylyan E. A. , Glazkov I. S. , Rumyantceva Z. S.
Published: June 2020

About 20 years ago osteoimmunology was identified as new field of scientific knowledge. It studies patterns of immune and bone system interactions in normal and pathological conditions. The osteoimmunology achievements have fundamentally changed our ideas about the pathogenesis of human skeleton diseases, including osteoporosis. This review presents cytokines key role in physiological and pathological bone remodeling. The issues of interaction between cytokines, osteoblasts and osteoclasts are described in detail. The crucial role of proinflammatory cytokines increased production by immunocompetent cells in the postmenopausal osteoporosis development has been characterized. Pubmed, Scopus, Web of Science, MedLine, eLIBRARY.RU databases were used for systematic literature search.
Adipokine profi le in patients with ischemic heart disease in stenting of the coronary arteries: contribution of changes in psychoemotional status
Authors: Lobe A. O. , Ivanchenko D. N. , Dorofeeva N. P. , Sizyakina L. P. , Kharitonova M. V. , Shlyk S. V.
Published: June 2020

Objective: to investigate the adipokine profile’s changes, depending on the presence or absence the signs of psychoemotional disorders in the form of associated affective symptoms in patients with stable coronary heart disease (CHD) without diagnosed carbohydrate metabolism’s disorders undergoing routine percutaneous coronary intervention (PCI) with stenting, and also to assess their relationship with clinical outcomes within 1 year after hospitalization.

Materials and methods: the study included 20 male patients with stable angina pectoris of functional classes II – III, hospitalized for coronary stenting. The severity of affective symptoms were being assessed. The levels markers of adiponectin, leptin, resistin in the blood plasma were determined before PCI and on the 3rd day after the operation.

Results: patients with stable coronary artery disease had increase in resistin concentrations and a decrease in adiponectin levels compared with reference. The change of psychoemotional status was accompanied by an initially more expressed increase in the concentrations of plasma resistin. The resistin’s level has been signifi cantly increased on the third day after PCI in patients without depressive symptoms. The dynamics of depressive symptoms hasn’t observed during the year. Clinically unfavorable outcomes, including stent’s restenosis, re-hospitalization, and the increase in angina attacks, were recorded more oft en in patients with subclinical symptoms of depression that persisted throughout the observation period.

Conclusions: the factors that negatively aff ected the cardiac prognosis were the disorders of the psychoemotional status and adipokine’s changes, including аn increasе of resistin’s and a decrease of adiponectin’s levels.
Assessment of the functional state of the microvasculature in children with diabetes mellitus type 1
Authors: Malyuzhinskaya N. V. , Stepanenko K. V. , Volchansky E. I.
Published: June 2020

Objective: to assess the functional state of the microvasculature in children with diabetes mellitus type 1 (DM type 1).

Materials and methods: 63 children with a verifi ed diagnosis of diabetes mellitus type 1 were examined. Th e control group consisted of 30 practically healthy children. Methods: clinical, paraclinical (determination of glycated hemoglobin level, study of microcirculation indicators using laser Doppler fl owmetry (LDF), statistical.

Results: microcirculatory disorders accompanying the course of diabetes mellitus type 1 depending on the length of illness were identifi ed. In children with diabetes mellitus type 1 with standing less than 3 years an increase in the average modulation of blood fl ow mainly due to passive regulation mechanisms and the predominance of hypera adaptation in assessing the functional states of microcirculation of varying severity with an increase in the energy of oscillatory processes were observed. Signs of non-nutritive hyperemia in the zone rich in arteriovenous anastamoses and a decrease in perfusion due to an increase in perfusion fl uctuations and coeffi cient of variation in the distal extremities, as well as a decrease in amplitudes in the active tone-forming range, a gradual decrease in the energy of oscillations and randomness criteria were diagnosed with standing in the duration of the disease.

Conclusions: disorders in children with diabetes mellitus type 1 microcirculatory detected using LDF are staged. Th e contribution of non-nutritive blood fl ow to microcirculation increases as the disease progresses, which leads to tissue hypoxia. Evaluation of the combination of energy, information and non-linear parameters of the oscillatory component of the blood flow allows you to identify the type of functional state in the microcirculation system.
Artificial Intelligence Education and Tools for Medical and Health Informatics Students: Systematic Review (Preprint)
Authors: Sapci A Hasan , Sapci H Aylin
Published: June 2020

BACKGROUND

The use of artificial intelligence (AI) in medicine will generate numerous application possibilities to improve patient care, provide real-time data analytics, and enable continuous patient monitoring. Clinicians and health informaticians should become familiar with machine learning and deep learning. Additionally, they should have a strong background in data analytics and data visualization to use, evaluate, and develop AI applications in clinical practice.

OBJECTIVE

The main objective of this study was to evaluate the current state of AI training and the use of AI tools to enhance the learning experience.

METHODS

A comprehensive systematic review was conducted to analyze the use of AI in medical and health informatics education, and to evaluate existing AI training practices. PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols) guidelines were followed. The studies that focused on the use of AI tools to enhance medical education and the studies that investigated teaching AI as a new competency were categorized separately to evaluate recent developments.

RESULTS

This systematic review revealed that recent publications recommend the integration of AI training into medical and health informatics curricula.

CONCLUSIONS

To the best of our knowledge, this is the first systematic review exploring the current state of AI education in both medicine and health informatics. Since AI curricula have not been standardized and competencies have not been determined, a framework for specialized AI training in medical and health informatics education is proposed.
Initial Model for Impact of Social Distancing on CoVID-19 Spread (Preprint)
Authors: Eng Genghmun
Published: June 2020

UNSTRUCTURED

The initial stages of the CoVID-19 coronavirus pandemic all around the world exhibit a nearly exponential rise in the number of infections with time. Planners, governments, and agencies are scrambling to figure out "How much? How bad?" and how to effectively treat the potentially large numbers of simultaneously sick people. Modeling the CoVID-19 pandemic using an exponential rise implicitly assumes a nearly unlimited population of uninfected persons ("dilute pandemic"). Once a significant fraction of the population is infected ("saturated pandemic"), an exponential growth no longer applies. A new model is developed here, which modifies the standard exponential growth function to account for factors such as Social Distancing. A Social Mitigation Parameter [SMP] α/s\ is introduced to account for these types of society-wide changes, which can modify the standard exponential growth function, as follows:
N(t)= No exp[ +Ko t/(1 + α/s\ t)] .
The doubling-time t/dbl\=(ln2)/Ko can also be used to substitute for Ko, giving a {t/dbl\, α/s\} parameter pair for comparing to actual CoVID-19 data. This model shows how the number of CoVID-19 infections can self-limit before reaching a saturated pandemic level. It also provides estimates for: (a) the timing of the pandemic peak, (b) the maximum number of new daily cases that would be expected, and (c) the expected total number of CoVID-19 cases. This model shows fairly good agreement with the presently available CoVID-19 pandemic data for several individual States, and the for the USA as a whole (6 Figures), as well as for various countries around the World (9 Figures). An augmented model with two Mitigation Parameters, α/s\ and β/s\, is also developed, which can give better agreement with the daily new CoVID-19 data. Data-to-model comparisons also indicate that using α/s\ by itself likely provides a worst-case estimate, while using both α/s\ and β/s\ likely provides a best-case estimate for the CoVID-19 spread.
Forecast of COVID-19 Cases in Nigeria: An implementation of an ARIMA model (Preprint)
Authors: Ameye Sanyaolu , Awoleye Michael , Agogo Emmanuel , Etuk Ette
Published: June 2020

BACKGROUND

The Coronavirus disease 2019 (COVID-2019) is a global pandemic and Nigeria is not left out in being affected. Though, the disease is just over three months since first case was identified in the country, we present a predictive model to forecast the number of cases expected to be seen in the country in the next 100 days.

OBJECTIVE

To implement a predictive model in forecasting the near future number of positive cases expected in the country following the present trend

METHODS

We performed an Auto Regressive Integrated Moving Average (ARIMA) model prediction on the epidemiological data obtained from Nigerian Centre for Disease Control to predict the epidemiological trend of the prevalence and incidence of COVID-2019.

RESULTS

There were 93 time series data points which lacked stationarity. From our ARIMA model, it is expected that the number of new cases declared per day will keep rising and towards the early September, 2020, Nigeria is expected to have well above sixty thousand confirmed cases.

CONCLUSIONS

We however believe that as we have more data points our model will be better fine-tuned.
Cremation based estimates suggest significant under- and delayed reporting of COVID-19 epidemic data in Wuhan and China (Preprint)
Authors: He Mai , Li Li , Dehner Louis P , Dunn Lucia
Published: June 2020

BACKGROUND

China’s COVID-19 statistics fall outside of recognized and accepted medical norms.

OBJECTIVE

Here we estimated the incidence, death and starting time of the COVID-19 outbreak in Wuhan and China based on cremation related information.

METHODS

Data sources included literature on COVID-19 in China, official Chinese government figures, state-run and non state-run media reports. Our estimates are based on investigative media reports of crematory operations in Wuhan, which is considered as a common data end point to life. A range of estimates is presented by an exponential growth rate model from lockdown (Jan 23,2020) until the intervention started to show effects, which was estimated 14.5 days after lockdown.

RESULTS

For the cumulative infections and total deaths, under different assumptions of case fatality rates (from 2.5% to 10%) and doubling time 6.4 days, the estimates projected on February 7, 2020 in Wuhan range from 305,000 to 1,272,000 for infections and from 6,811 to 7,223 for deaths - on the order of at least 10 times the official figures (13,603 and 545). The implied starting time of the outbreak is October 2019. The estimates of cumulative deaths, based on both funeral urns distribution and continuous full capacity operation of cremation services up to March 23, 2020, give results around 36,000, more than 10 times of the official death toll of 2,524.

CONCLUSIONS

Our study indicates a significant under-reporting in Chinese official data on the COVID-19 epidemic in Wuhan in early February, the critical time for response to the COVID-19 pandemic.

CLINICALTRIAL

Not applicable
Social Media as Potential Means in Increasing Knowledge on Low Birth Weight Babies (LBWB) among Adolescents : A Cross Sectional Study (Preprint)
Authors: Erindriani Frina , Pratomo Hadi , Siregar Kemal Nazarudin , Amelia Tiara
Published: June 2020

BACKGROUND

LBWB is birth weight of less than 2500 grams. New born mortality is 50% higher with adolescent mothers. Adolescents who give birth at the age of 15–19 years have a higher risk of neonatal death. Nowadays, adolescents are easily accessed as they use social media in their daily lives.

OBJECTIVE

This study aims to determine social media as potential means in increasing knowledge on LBWB among adolescents.

METHODS

This study was cross sectional with total respondent was 286 adolescents aged 16–18 from 2 schools (urban and rural). Chi square and Logistic Regression analysis were used in this study.

RESULTS

The research show that 108 (75.5%) of respondents in urban and 61 (42.7%) in rural area respondents have access social media. Mostly adolescent in urban use Instagram while in rural use Facebook to seek out LBWB knowledge. Even though, 92.7% of adolescents had heard the term premature baby, only 24.5% of respondents knew what is the normal range gestational age. There is a significant relationship between social media and knowledge of LBW (p-0.01). Based on multivariate analysis, adolescents who have high access to social media have a 3.047 times higher of having high knowledge of LBWB in comparison to those who have low access.

CONCLUSIONS

This study shows that social media has potential means in order to increase LBWB knowledge among adolescent. Mostly adolescent in urban use Instagram while in rural use Facebook.
Empirical Model of Spring 2020 Decrease in Daily Confirmed COVID-19 Cases in King County, Washington (Preprint)
Authors: Roach Jared C
Published: June 2020

BACKGROUND

Projections of the near future of daily case incidence of COVID-19 are valuable for informing public policy. Near-future estimates are also useful for outbreaks of other diseases and other outcome measures. Short-term predictions are unlikely to be affected by changes in herd immunity. Both phenomenological and mechanistic models are valid approaches for epidemiology depending on the amount of available data and how much of the mechanism is known. Phenomenological models have fallen out of favor in recent decades.

OBJECTIVE

To produce an empirical exponential model of the COVID-19 outbreak in King County, Washington during Spring 2020.

METHODS

Confirmed case-count data from Public Health – Seattle & King County were fit to an exponential model with non-linear regression.

RESULTS

Using an exponential model, incidence-count half-life (t1/2) is a more precise statistic than R because it does not require propagating uncertainty estimates from unmeasured variables. The parameters and predictions of this model remained stable for 77 days from March 26 to June 10, 2020 during a period of consistent public health policy.

CONCLUSIONS

In the absence of major net changes in factors that affect reproduction number (R), the two-parameter exponential model should be a standard model. This model had been standard for epidemiological analysis of pandemics since the early twentieth century but in recent decades has lost popularity to more complex compartmental models. An exponential model should be routinely included in reports describing epidemiological models as a reference, or null hypothesis. Exponential models should be fitted separately for time intervals that differ by any major changes in factors that affect R.
Public Perception of the COVID-19 Pandemic on Twitter: Sentiment Analysis and Topic Modeling Study (Preprint)
Authors: Boon-Itt Sakun , Skunkan Yukolpat
Published: June 2020

BACKGROUND

COVID-19 is a scientifically and medically novel disease that is not fully understood because it has yet to be consistently and deeply studied. Among the gaps in research on the COVID-19 outbreak, there is a lack of sufficient infoveillance data.

OBJECTIVE

The aim of this study was to increase understanding of public awareness of COVID-19 pandemic trends and uncover meaningful themes of concern posted by Twitter users in the English language during the pandemic.

METHODS

Data mining was conducted on Twitter to collect a total of 107,990 tweets related to COVID-19 between December 13 and March 9, 2020. The analyses included frequency of keywords, sentiment analysis, and topic modeling to identify and explore discussion topics over time. A natural language processing approach and the latent Dirichlet allocation algorithm were used to identify the most common tweet topics as well as to categorize clusters and identify themes based on the keyword analysis.

RESULTS

The results indicate three main aspects of public awareness and concern regarding the COVID-19 pandemic. First, the trend of the spread and symptoms of COVID-19 can be divided into three stages. Second, the results of the sentiment analysis showed that people have a negative outlook toward COVID-19. Third, based on topic modeling, the themes relating to COVID-19 and the outbreak were divided into three categories: the COVID-19 pandemic emergency, how to control COVID-19, and reports on COVID-19.

CONCLUSIONS

Sentiment analysis and topic modeling can produce useful information about the trends in the discussion of the COVID-19 pandemic on social media as well as alternative perspectives to investigate the COVID-19 crisis, which has created considerable public awareness. This study shows that Twitter is a good communication channel for understanding both public concern and public awareness about COVID-19. These findings can help health departments communicate information to alleviate specific public concerns about the disease.
Determinan Status Gizi Obesitas pada Orang Dewasa di Perkotaan: Tinjauan Sistematis
Authors: Safitri Debby Endayani , Rahayu Nur Setiawati
Published: June 2020

ABSTRAK

Obesitas dapat berdampak pada peningkatan risiko terjadinya penyakit tidak menular hingga penurunanproduktivitas. Obesitas diduga dipengaruhi oleh berbagai faktor. Wilayah perkotaan memiliki beberapa perbedaan dengan wilayah pedesaan dari berbagai aspek, seperti kegiatan perekonomian maupun gaya hidup yang memungkinkan risiko yang lebih besar untuk terjadinya obesitas dibandingkan dengan wilayah pedesaan. Penelitian ini menggunakan metode systematic review, untuk merangkum hasil penelitian mengenai obesitas di wilayah perkotaan yang dipublikasikan pada sepuluh tahun terakhir. Determinan obesitas pada wilayah perkotaan meliputi faktor internal dan faktor eksternal. Faktor internal dikelompokkan sebagai perilaku konsumsi dan aktivitas, sikap, serta karakteristik individu. Faktor eksternal terdiri dari dukungan keluarga dan lingkungan sekitar individu.

Kata kunci : Obesitas, Dewasa, Perkotaan
Análisis exploratorio sobre la apreciación de características predominantes en empresas medianas de México y Colombia en temas de calidad, competitividad, innovación social y productiva
Authors: Cruz Páez Fabio Orlando , Ibarra Díaz Celia , Rueda Pineda Danna Julieth , Olivares Vera Daniel Arturo
Published: June 2020

El artículo de investigación muestra la identificación de características de mayor impacto en empresas medianas de México y Colombia frente a la Calidad,Competitividad, Innovación Social y Productividad, el tipo de investigación aplicada es cuasiexperimental, el corte de la investigación es cuantitativo, encuesta Delphi aplicad a 35 expertos del tema en Colombia y México, el diseño de la investigación es transversal, el alcance de la investigación es descriptivo de las variables teóricas calidad, innovación social y competitividad y análisis estadístico de datos con el software R®, finalmente el uso de herramientas de la calidad en las empresas medianas de México y Colombia en la implementación de estrategias de calidad evidencia que satisfacen las necesidades de la comunidad interna y externa de las entidades desde la planeación estratégica en los sistemas de gestión de calidad con innovación social y productiva fortaleciendo los procesos, procedimientos y la seguridad social del capital humano en medianas empresas de Colombia y México.
Grupo de investigación Identidad Contable: Una revisión de la producción académica en la generación de conocimiento
Authors: Córdoba Martínez Jorge Xavier , Villarreal José Luis
Published: June 2020

Los grupos de investigación son dinamizadores del conocimiento, promueven la indagación, reflexión e innovación para identificar situaciones problemáticas,dar respuesta a las necesidades del ser humano y socio empresariales, a la vez son factores diferenciadores de la calidad educativa en la universidad del siglo XXI. El objetivo es describir la línea de investigación en ciencias de gestión, a partir de los aportes del grupo Identidad Contable, al fortalecimiento de la investigación de la disciplina contable y su interacción con redes de conocimiento de carácter nacional e internacional.

La ruta metodológica recorrida es de tipo cualitativo, basada en la revisión bibliográfica que permita plantear discusiones en torno a la construcción deconocimiento para el desarrollo de la investigación desde el suroccidente colombiano. Consecuentemente, en los resultados se identifican los aportes deinvestigaciones disciplinares y aplicadas, unido a la promoción del pensamiento y compromiso profesional como factores de la transformación social y cuidadoambiental.
Liposomal drug delivery system as an effective treatment approach for lung cancer
Authors: Patel Kinjal , Patel Devanshi
Published: June 2020

Worldwide, cancer is one of the leading causes of mortality and cancer rates are set to increase at alarming rate globally. There are various types of cancer in which the leading type is the lung cancer.   In recent years lipid-based carriers, such as liposomes, have successfully encapsulated chemotherapeutic agents ameliorating some toxicity issues, while enhancing the overall therapeutic activity in cancer patients. In addition to this, nanomaterials can help to improved half-life in the body, morphology, for increased drug loading and many other ways. The survey discussed in this review will lead the anticancer therapy and cancer management which will provide the platform to the next generation.  Therefore, this critical review includes the therapeutic interventions, liposomes target delivery, active and passive drug loading. Finally, we attempt to summarize the current challenges in nanotherapeutics and provide an outlook on the future of this important field.

Keywords: Drug Delivery, Liposomes target Delivery, Nanostructures, Drug loading
Conflict, Traditional, and Family Resistance: The pattern of Dispute Resolution in Acehnese Community According to Islamic Law
Authors: Djawas Mursyid , Abdul Samad Sri Astuti
Published: June 2020

This study discusses the resolution of disputes through adat and family security in Acehnese society according to Islamic law. The problems examined are the pattern of resolving family conflicts through adat mechanisms in Aceh; The relationship between resolving conflicts through adat and family resilience in Aceh and a review of Islamic law towards resolving family conflicts through adat in Aceh. This study uses a qualitative approach, which is to explain, describe, and analyze in-depth the results of research. Data collection techniques used were literature study and interviews with informants. While the data were analyzed using Islamic legal theory and traditional law. This research concludes that there are several patterns for example involving various parties such as Jurong, Keuchik, Tuha Peut, Teungku Imum, Imum Mukim, and the place of dispute resolution at meunasah sometimes at Keuchik's house. There is a close relationship between resolving disputes through adat and family resilience, meaning that many family problems that are resolved through adat mechanisms do not go through formal legal avenues. Then the dispute resolution is in line with Islamic law which is included in the urf category with a review of the benefits.
Prison in Review of Islamic Criminal Law: Between Human and Deterrent Effects
Authors: Haq Islamul
Published: June 2020

This study aims to find out how the prison system is in Islamic criminal law and how to treat prisoners in Islamic criminal law. This research is a qualitative study using a philosophical approach. The analysis of this research uses descriptive analysis method. The results of this study indicate that Islam views prison as a type of takzir punishment. with imprisonment, a prisoner can get a deterrent effect. However, that does not mean that prisoners are treated inhumanely. Islam has principles and ethics that apply to prisoners. One of the noble guidelines of Islam is to treat prisoners well, but is not privileged.
Revitalizing the Role and Function of the Mosque as a Center for Da'wah Activities and Community Development
Authors: Usman Iskandar
Published: June 2020

Prophet Muhammad SAW was the first to build a mosque and he has given a very strategic role to the mosque and functioned optimally as a center for da'wah and fostering activities of the people. The Prophet Muhammad SAW was the bearer of the Divine message which was the most successful in conveying Islamic teachings and the most successful in fostering the Ummah. In less than 23 years, Rasulullah SAW succeeded in conveying the teachings of Islam perfectly and gained a very large number of followers and at the same time managed to foster the ummah into a civil society with high civilization and noble character. From one of the first mosques built by Rasulullah SAW in Quba, there are now millions of mosques throughout the world. But the role and function of mosques in general have experienced a lot of degradation, less functioning as a center of worship and Islamic culture, as practiced by Rasulullah SAW, more mosques only function as places of worship, instead there are mosques which are only used as places for Friday prayers, whereas prayer the other five times are not held in the mosque in congregation, because Muslims are not disciplined in keeping their prayers in congregation. This article would like to convey some thoughts, ideas, and ideas for the revitalization of the mosque as a center for preaching and fostering activities of the people.
"Esse universo dos sons que a gente não escuta”: entrevista com Cildo Meireles
Authors: Leite Caroline Alciones de Oliveira
Published: June 2020

Desde janeiro de 2019, temos tido a oportunidade de realizar uma série de entrevistas com Cildo Meireles, além de outras visitas ao ateliê do artista. Esta entrevista, a primeira da série, trata do sonoro em diversas obras de Cildo Meireles, desde o final da década de 1960 até a década de 2010. O desenrolar da entrevista se dá entremeado por reticências que contemplam conversas paralelas à questão sonora e também muitas risadas com o artista e seus assistentes.
Attitudes Toward Family Medicine Among Students Choosing Other Primary Care Specialties
Authors: Prunuske Jacob , Kang Hana , Wendling Andrea L. , Edwards-Johnson Jennifer , Phillips Julie P.
Published: June 2020

Background and Objectives: Little is known about how medical students choose between primary care specialties. We compared the attitudes toward family medicine of medical students intending to practice primary care but not family medicine (PCNFM), with students intending to practice family medicine (FM) and those intending nonprimary care (NPC) careers.
Methods: The Family Medicine Attitudes Questionnaire (FMAQ) was distributed to 2,644 fourth-year medical students at 16 medical schools in spring 2017. Respondents were stratified by career intention. In this secondary data analysis, we used descriptive statistics to characterize responses to each questionnaire item and FMAQ total score, and analysis of variance with Bonferroni post hoc analyses to compare category and item mean responses.
Results: Of 2,644 fourth-year medical students who received the FMAQ, 1,188 (41.8%) submitted usable responses. The 14-item FMAQ has a maximum score of 70. Mean total scores differed by category: 59.05 for FM, 52.88 for NPC, and 54.83 for PCNFM (F=108.96, P<.01); the differences between each possible pairing were significant (P<.05). Comparing the responses of students intending PCNFM careers with those of students intending NPC careers, there were no differences in mean responses for 8 of 14 FMAQ items. Responses of students intending PCNFM careers were similar to students intending FM for only 4 of 14 items (P<.05).
Conclusions: Fourth-year students intending to match into PCNFM have attitudes toward FM that more closely approximate the attitudes of NPC students than the attitudes of FM students. Future research should explore implications for curricular development, student mentorship, and career advising.