bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of Glucopyranosyl Schiff Base Zinc(II) Complexes Capable of Interacting with Mononucleotides, and Their DNA‐Cleavage Activities
Authors: Nakai Misaki , Fukuda Hironobu , Yano Shigenobu , Nakabayashi Yasuo
Published: September 2012

New glucopyranosyl Schiff base zinc complexes, [Zn(GlcSal)2] (1; GlcSalH=N‐(2‐deoxy‐β‐D‐glucopyranos‐2‐yl‐salicylaldimine) and [Zn(AcOGlcSal)2] (2; AcOGlcSalH=N‐(2‐deoxy‐β‐D‐1,3,4,6‐tetraacetylglucopyranos‐2‐yl‐salicylaldimine) were synthesized, and characterized by spectral and analytical methods. The interaction between the Zn complexes and mononucleotides was investigated by 1H‐NMR, 31P‐NMR and UV/VIS spectroscopies. Mononucleotides, cytidine 5′‐monophosphate (CMP) and uridyl 5′‐monophosphate (UMP), interacted with these complexes to form a 1 : 1 complex with 1 and a 1 : 2 complex with 2, depending on the presence of the OH group of glucopyranosyl substituents. The DNA‐cleavage activities of 1 and 2 were studied using plasmid DNA (pBR322) in a medium of 5 mM Tris⋅HCl/50 mM NaCl buffer in the presence of H2O2. The DNA‐cleavage activity decreased in the order of 2>1>Zn(OAc)2, indicating the significant promoting effect of the glucopyranosyl Schiff base ligand and the participation of the glucopyranosyl OH groups in the cleavage mechanism. The mechanism of the DNA cleavage by 1 and 2 was investigated by evaluation of the effect of a HO. radical scavenger and a singlet‐oxygen (1O2) quencher under aerobic conditions. The former exhibited little effect, excluding the HO. radical as an active species and supporting the hydrolysis mechanism for the main process of the DNA cleavage. The latter quencher somewhat hindered the cleavage, indicating the partial participation of a 1O2 as a competitive active species in the present system.
X‐Ray Crystal Structure of a Mutant Assimilatory Nitrite Reductase That Shows Sulfite Reductase‐Like Activity
Authors: Nakano Shogo , Takahashi Misa , Sakamoto Atsushi , Morikawa Hiromichi , Katayanagi Katsuo
Published: September 2012

Assimilatory nitrite reductase (aNiR) reduces nitrite ions (NO) to ammonium ions (NH), whereas assimilatory sulfite reductase reduces sulfite (SO) to hydrogen sulfide (HS−). Although aNiR can also reduce SO, its activity is much lower than when NO is reduced as the substrate. To increase the SO‐reduction activity of aNiR, we performed a N226K mutation of Nii3, a representative aNiR. The resulting Nii3‐N226K variant could bind non‐native targets, SO, and HCO, in addition to its native target, i.e., NO. We have determined the high‐resolution structure of Nii3‐N226K in its apo‐state and in complex with SO, NO, and HCO. This analysis revealed conformational changes of Lys226 and the adjacent Lys224 upon binding of SO, but not NO. In contrast, HCO binding induced a conformational change at Arg179. After replacing Asn226 with a positively charged Lys, aNiR showed affinity for several anions. A comparison of all ligand‐bound structures for Nii3‐N226K revealed that structural changes in the active site depend on the size of the substrate.
Quinoline‐Based, Glucose‐Pendant Fluorescent Zinc Probes
Authors: Mikata Yuji , Ugai Anna , Yasuda Keiko , Itami Saori , Tamotsu Satoshi , Konno Hideo , Iwatsuki Satoshi
Published: September 2012

Quinoline‐based tetradentate ligands with glucose pendants, N,N′‐bis[2‐(β‐d‐glucopyranosyloxy)ethyl]‐N,N′‐bis[(6‐methoxyquinolin‐2‐yl)methyl]ethylenediamine (N,N′‐6‐MeOBQBGEN) and its N,N‐counterpart, N,N‐6‐MeOBQBGEN, have been prepared, and their fluorescence‐spectral changes upon Zn binding were investigated. Upon excitation at 336 nm, N,N′‐6‐MeOBQBGEN showed weak fluorescence (ϕ≈ 0.016) in HEPES buffer (HEPES 50 mM, KCl 100 mM, pH 7.5). In the presence of Zn, N,N′‐6‐MeOBQBGEN exhibited a significant increase in fluorescence (ϕ=0.096) at 414 nm. The fluorescence enhancement is specific for Zn and Cd (ICd/IZn of 50% at 414 nm). On the other hand, N,N‐6‐MeOBQBGEN exhibited a smaller fluorescence enhancement upon Zn complexation (ϕ=0.043, λex=334 nm, λem=407 nm) compared with N,N′‐6‐MeOBQBGEN. Fluorescence microscopic analysis using PC‐12 rat adrenal cells revealed that N,N′‐6‐MeOBQBGEN exhibits a 1.8‐fold higher fluorescence‐signal response to Zn ion concentration compared with sugar‐depleted compound 2 (N,N′‐bis[(6‐methoxyquinolin‐2‐yl)methyl]ethylenediamine), due to its enhanced uptake into cells due to the targeting ability of the attached carbohydrates.
Group‐10 Metal Complexes of Biological Molecules and Related Ligands: Structural and Functional Properties
Authors: Shimazaki Yuichi , Yamauchi Osamu
Published: September 2012

The complexes of group‐10 metals, Ni, Pd, and Pt, with biological molecules and related ligands have been attracting increasing attention in recent years due to their reactivities and functions, such as catalysts and drugs, and their biological relevance. The well‐defined structures and kinetic inertness especially of Pt complexes have been used as the sites for weak interactions with other molecules. The Ni complexes have been reported as models not only for Ni enzymes but also for other metalloenzyme active sites for deeper understanding of the reactivities such as oxygen activations and detailed electronic structures. Pd Complexes are widely known for their catalytic activities in conversions of various organic molecules including useful biological molecules, such as SuzukiMiyaura cross‐coupling, while Pt complexes have been intensively studied for their antitumor activities. We focus in this review on our recent results on weak interactions and reactivities of the group‐10 metal complexes with biological molecules and related compounds, and discuss their structural features and some new properties pointing to functional possibilities.
Coordination of Thiosemicarbazones and Bis(thiosemicarbazones) to Bismuth(III) as a Strategy for the Design of Metal‐Based Antibacterial Agents
Authors: Lessa Josane A. , Reis Débora C. , Da Silva Jeferson G. , Paradizzi Lúcia T. , da Silva Nayane F. , de Fátima A. Carvalho Mariany , Siqueira Sarah A. , Beraldo Heloisa
Published: September 2012

Complexes [Bi(2Fo4Ph)Cl2] (1), [Bi(2Ac4Ph)Cl2] (2), [Bi(2Bz4Ph)Cl2] (3), [Bi(H2Gy3DH)Cl3] (4), [Bi(H2Gy4Et)(OH)2Cl] (5), and [Bi(H2Gy4Ph)Cl3] (6) were prepared with pyridine‐2‐carbaldehyde 4‐phenylthiosemicarbazone (H2Fo4Ph), 1‐(pyridin‐2‐yl)ethanone 4‐phenylthiosemicarbazone (H2Ac4Ph), phenyl(pyridin‐2‐yl)methanone 4‐phenylthiosemicarbazone (H2Bz4Ph), as well as with glyoxaldehyde bis(thiosemicarbazone) (H2Gy4DH) and its 4‐Et (H2Gy4Et) and 4‐Ph (H2Gy4Ph) derivatives. The complexes exhibited antibacterial activities against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Pseudomonas aeruginosa. Coordination to BiIII proved to be an effective strategy to increase the antibacterial activity of the thiosemicarbazones and bis(thiosemicarbazones).
Mono(maleonitriledithiolene)molybdenum(IV) and Bis(μ‐sulfido)‐Bridged Dimolybdenum(V) Complexes with MoS Moiety
Authors: Bose Moumita , Moula Golam , Sarkar Sabyasachi
Published: September 2012

Mono(maleonitriledithiolene)sulfidomolybdenum(IV) complex, [MoS(S4)(mnt)]2− (2; mnt=maleonitriledithiolene) was synthesized by the substitution reaction of a tetrasulfido ligand of the known [MoS(S4)2]2− (1) upon reaction with one or even excess equivalent of Na2(mnt) in aqueous MeCN solution in air. Surprisingly, 2 undergoes dimerization on treatment with alkyl halide such as MeI and PhCH2Br to form bis(μ‐sulfido)dimolybdenum(V) species, [{MoS(mnt)}2(μ‐S)2]2− (3). These complexes have been characterized by IR, UV/VIS spectroscopy, cyclic voltammetry, elemental analysis, and by X‐ray crystal‐structure analysis. Differences in the relative stability and electrochemical behavior of 1, 2, and 3 have been correlated with theoretical calculations at DFT level.
Organometallic Ruthenium and Osmium Compounds of Pyridin‐2‐ and ‐4‐ones as Potential Anticancer Agents
Authors: Henke Helena , Kandioller Wolfgang , Hanif Muhammad , Keppler Bernhard K. , Hartinger Christian G.
Published: September 2012

Organometallic RuII compounds are among the most widely studied anticancer agents. Functionalizing metal centers with biomolecule‐derived ligands has been shown to be a promising strategy to improve the antiproliferative activity of metal‐based chemotherapeutics. Herein, the synthesis of a series of novel 3‐hydroxypyridin‐2‐one‐derived ligands and their MII(η6‐p‐cymene) half‐sandwich complexes (M=Ru, Os) is described. The compounds were characterized by 1D‐ and 2D‐NMR spectroscopy, and elemental analysis.
Diamminetetrakis(carboxylato)platinum(IV) Complexes – Synthesis, Characterization, and Cytotoxicity
Authors: Hoffmeister Björn R. , Adib‐Razavi Mahsa S. , Jakupec Michael A. , Galanski Mathea Sophia , Keppler Bernhard K.
Published: September 2012

A series of eight novel diamminetetrakis(carboxylato)platinum(IV) complexes was synthesized and characterized by multinuclear 1H‐, 13C‐, 15N‐, and 195Pt‐NMR spectroscopy. Their antiproliferative potency was evaluated in three human cancer cell lines representing ovarian (CH1), lung (A549), and colon carcinoma (SW480). In cisplatin‐sensitive CH1 cancer cells, cytotoxicity was found in the low micromolar range, whereas, in inherently cisplatin‐resistant A549 and SW480 cells, the activity was very low or negligible. Astonishingly, raise in lipophilicity of the complexes, as found in the case of cisplatin analogs, did not result in a significant enhancement of the cytotoxic effect.
Binding of Divalent Metal Ions to Calcium‐Free Peroxidase: Thermodynamic and Kinetic Studies
Authors: Nazari Kohdadad , Kelay Vahid , Mahmoudi Ali , Hashemianzadeh Seyed Majid
Published: September 2012

Thermodynamics of binding of divalent metal ions including Ca2+, Mg2+, Ba2+, and Cd2+ to Ca‐free horseradish peroxidase (HRP) enzyme was investigated using UV/VIS spectrophotometry and molecular‐mechanic (MM) calculations. According to the obtained binding and thermodynamic parameters, trend of the relative binding affinities of these divalent metal cations was found to be: Ca2+>Cd2+>Mg2+>Ba2+. Binding analysis based on Scatchard and Hill models showed positive cooperativity effect between the two distal and proximal binding sites. Furthermore, kinetics of binding and reconstitution process was examined (using relaxation‐time method) for binding of Ca2+ (as the typical metal ion) to Ca‐free HRP, which was found a second‐order type having a two‐step mechanism involving fast formation of Ca‐free HRP/1 Ca2+ as the kinetic intermediate in step 1. Finally, by means of MM calculations, the comparative stability energies were evaluated for binding of M2+ metal cations to Ca‐free HRP. Based on MM calculations, preferential binding of Ca2+ ion was occurred on distal and proximal binding sites of Ca‐free HRP associated with higher stability energies (Etotal). Indeed, among the divalent metal ions, Ca2+ with the highest binding affinity (maximum value of Kbin and minimum value of ΔG), maximum value of exothermic binding enthalpy, and stability energies stabilizes the HRP structure along with an optimized catalytic activity.
Density Functional Study on UV/VIS Spectra of Copper‐Protein Active Sites: The Effect of Mutations
Authors: Swart Marcel , Johansson Mikael P.
Published: September 2012

UV/VIS Electron excitation spectra have been computed for large, realistic model systems of the blue copper protein family. Fully quantum‐chemical calculations at the density‐functional theory level employing polarized triple‐ζ basis sets have been performed on systems of over 120 atoms, without symmetry. Different mutants, with the ligating methionine of the wild type Cu center exchanged for histidine (M121 H) and glutamine (M121Q), have been investigated in order to obtain insight about how the influence of the exact surrounding milieu of the Cu‐atom affects the computed spectrum. With sufficiently large model sizes, inclusion of the environment by using continuum solvation models do not change the spectra significantly. More direct and rigorous treatments are needed to reliably assess the effect of the surrounding protein on the electronic structure of the active sites.
Efficient Room‐Temperature O‐Silylation of Alcohols Using a SBA‐15‐Supported Cobalt(II) Nanocatalyst
Authors: Rajabi Fatemeh , Luque Rafael , Serrano‐Ruiz Juan Carlos
Published: September 2012

The O‐silylation of OH groups of alcohols and phenols with hexamethyldisilazane (HMDS) was achieved in high‐to‐excellent yields using catalytic quantities of a SBA‐15‐supported cobalt(II) nanocatalyst (typically 0.5 mol‐%) at room temperature and under solvent‐free conditions. Furthermore, the heterogeneous catalyst showed an excellent durability and can be conveniently reused by filtration for at least twelve times without any noticeable loss of activity.
The [(Cp)M(CO)3] (M=Re, 99mTc) Building Block for Imaging Agents and Bioinorganic Probes: Perspectives and Limitations
Authors: Can Daniel , Peindy N'Dongo Harmel W. , Spingler Bernhard , Schmutz Paul , Raposinho Paula , Santos Isabel , Alberto Roger
Published: September 2012

Starting from asymmetric Thiele's acid derivatives, two different imaging probes [99mTc(CO)3(CpR)] (R=potential targeting vector) are generated simultaneously in one‐pot and from one substrate. This extends the previously introduced labeling strategy of metal‐mediated retro‐DielsAlder reaction with HCp‐R dimers. We demonstrate that chemically active functionalities such as hydroxamic acids are not following this labeling strategy. Adopting the principle of replacing phenyl rings by [Re(CO)3(Cp)] entities, potent histone deacetylase (HDAC)‐inhibiting Re analogs of suberoylanlilide hydroxamic acid (SAHA; N‐hydroxy‐N′‐phenyloctanediamide) were synthesized and characterized. Cytotoxic evaluation on different tumor cell lines revealed low IC50 values [μM] for these compounds, comparable to their purely organic congeners.
Unprotected left main bifurcation restenosis treated with a 2‐stent technique
Authors: Wainstein Marco V. , Wainstein Rodrigo V. , Ribeiro Jorge P.
Published: September 2012

The present case report refers to the percutaneous treatment of severe left main stem stenosis as a consequence of proliferative in‐stent restenosis of left circumflex coronary with retrograde involvement. A reverse mini‐crush technique with 2 stents was described. © 2012 Wiley Periodicals, Inc.
Patients without prolonged QRS after TAVI with CoreValve device do not experience high‐degree atrio‐ventricular block
Authors: Mouillet Gauthier , Lellouche Nicolas , Lim Pascal , Meguro Kentaro , Yamamoto Masanori , Deux Jean‐François , Monin Jean‐Luc , Bergoënd Eric , Dubois‐Randé Jean‐Luc , Teiger Emmanuel
Published: September 2012

Objective

To identify clinical and electrical factors predicting delayed high‐degree atrio‐ventricular block (AVB) after transcatheter aortic valve implantation (TAVI).

Background

TAVI is a new technique for treating severe aortic valve stenosis in patients at high surgical risk but can be followed by high‐grade AVB requiring permanent pacing (PP).

Methods and Results

The study included 79 patients (82 ± 17 years, Euroscore = 23% ± 10%) free of PP need before and immediately after TAVI procedure. Delayed high‐degree AVB was defined by types 2 or 3 AVB diagnosed at least 24 hr after the index procedure. Permanent pacemaker implantation was performed for all these patients. We compared clinical and electrical variables before and after TAVI in patients with delayed AVB or not. TAVI was performed successfully in all patients. The 21 (26%) patients who exhibited delayed high‐grade AVB had significantly deeper prosthesis implantation (12 ± 4 mm vs. 9 ± 5 mm, P = 0.03) and wider post‐TAVI QRS duration (155 ± 17 msec vs. 131 ± 25 msec, P = 0.0004), with no difference in baseline QRS duration. Post‐TAVI QRS duration was the only independent predictor of post‐TAVI permanent for delayed high‐degree AVB (P = 0.02). After a mean follow‐up of 10 ± 8 months, all 21 patients with post‐TAVI QRS ≤128 msec were free of high‐grade AVB, whereas 21/55 (38%) patients with post‐TAVI QRS >128 msec had PP (P = 0.0016).

Conclusion

Delayed (>24 hr after the procedure) high‐grade AVB necessitating PP is common after TAVI. QRS duration measured immediately after TAVI was the best independent predictor of PP in this population. Patients with QRS ≤128 msec immediately after TAVI had no risk of requiring PP. © 2012 Wiley, Periodicals, Inc.
ChemInform Abstract: Luminescence Properties and Crystallographic Sites for Eu3+ Ions in Fluorthalenite Y3Si3O10F.
Authors: Jang Kyoung Hyuk , Khaidukov N. M. , Tuyen Vu Phi , Kim Sun Il , Yu Young Moon , Seo Hyo Jin
Published: September 2012

The new Y3Si3O10F:Eu3+ phosphor is hydrothermally synthesized from aqueous mixtures of Y2O3, Eu2O3, SiO2, and HF (autoclave, 250 °C, 120 h).
ChemInform Abstract: Ba2Bi1.4Nb0.6O6: A Nonferroelectric, High Premittivity Oxide.
Authors: Tan Chaou C. , Feteira Antonio , Sinclair Derek C.
Published: September 2012

Ba2Bi1.4Nb0.6O6 is characterized by a combination of variable temperature XRD and impedance spectroscopy.
ChemInform Abstract: Synthesis and Properties of Monocrystalline Al(As1‐xPx)Si3 Alloys on Si(100).
Authors: Grzybowski G. , Watkins T. , Beeler R. T. , Jiang L. , Smith D. J. , Chizmeshya A. V. G. , Kouvetakis J. , Menendez J.
Published: September 2012

The new title materials are grown on Si(100) at 490—500 °C as single‐phase epitaxial layers with monocrystalline diamond‐like structures using reactions of Al atomic beams with As(SiH3)3 and P(SiH3)3.
ChemInform Abstract: Calorimetric Investigation of New Bi12.5Dy1.5ReO24.5 Phase.
Authors: Matskevich Nata I. , Wolf Thomas
Published: September 2012

The title compound is prepared from a mixture of Bi2O3, Re2O7, and Dy2O3 (1070 K, 70 h) and characterized by XRD and calorimetric measurements.
ChemInform Abstract: Synthesis of Nitrided MoO2 and Its Application as Anode Materials for Lithium‐Ion Batteries.
Authors: Yoon Sukeun , Jung Kyu‐Nam , Jin Chang Soo , Shin Kyung‐Hee
Published: September 2012

Nitrided MoO2 is hydrothermally synthesized from a saturated (NH4)6Mo7O24 solution in HNO3 (autoclave, 200 °C, 35 h) followed by nitridation of the obtained MoO2 powders with NH3 gas for 12 h at 550—650 °C.
ChemInform Abstract: Synthesis and Characterization of α‐, β‐, and γ‐Ga2O3 Prepared from Aqueous Solutions by Controlled Precipitation.
Authors: Li Liandi , Wei Wei , Behrens Malte
Published: September 2012

α‐ and β‐Ga2O3 are prepared by calcination of α‐GaOOH at 350 and 700 °C, respectively.
ChemInform Abstract: Rapid Microwave Preparation of Thermoelectric TiNiSn and TiCoSb Half‐Heusler Compounds.
Authors: Stucky Galen D. , et al. et al.
Published: September 2012

The title compounds are synthesized from stoichiometric mixtures of the elements in a domestic microwave oven using granular carbon as microwave susceptor material (1 min) followed by a densification step involving hot‐pressing (84 MPa, 1173 K, 1 h).
ChemInform Abstract: Synthesis and Structure of a New Family of 3d‐4f Heterometallic Compounds Rb7LnFe6O2(PO4)8 (Ln: Sm, Eu, Gd, Dy): Magnetic Properties of the Sm‐, Gd‐, Dy‐Derivatives.
Authors: Sanjeewa Liurukara D. , West J. Palmer , Hwu Shiou‐Jyh
Published: September 2012

The title compounds are synthesized by reaction of Ln2O3 (Ln: Sm, Eu, Gd, Dy), Fe2O3, P4O10, and KO2 in an equimolar RbCl/RbI flux (evacuated silica tube, 800 °C, 2 d).
ChemInform Abstract: Ternary CaCu4P2‐Type Pnictides AAg4Pn2 (A: Sr, Eu; Pn: As, Sb).
Authors: Stoyko Stanislav S. , Khatun Mansura , Mullen C. Scott , Mar Arthur
Published: September 2012

The new title compounds are prepared by reactions of stoichiometric mixtures of the elements (alumina crucible, 850 °C, 1—4 d) and characterized by single crystal XRD.
ChemInform Abstract: Efficient, Low Cost Synthesis of Sodium Platinum Bronze NaxPt3O4.
Authors: Horwat David , Dehmas Moukrane , Gutierrez Alejandro , Pierson Jean‐Francois , Anders Andre , Soldera Flavio , Endrino Jose‐Luis
Published: September 2012

Large quantities of NaxPt3O4 are prepared with a purity higher than 95% by deposition of PtOy (magnetron sputtering in pure oxygen at a pressure of 4 Pa) on a soda lime glass followed by annealing in air at atmospheric pressure (above 550 °C).
ChemInform Abstract: “Bottom‐Up” Embedding of the Joergensen—Hayashi Catalyst into a Chiral Porous Polymer for Highly Efficient Heterogeneous Asymmetric Organocatalysis.
Authors: Wang Chang An , Zhang Zhi Kun , Yue Tao , Sun Ya Lei , Wang Lei , Wang Wei David , Zhang Yuan , Liu Chong , Wang Wei
Published: September 2012

The title catalyst, which contains both micropores and mesopores and wide openings and interconnected nanopores which ensure its activity.
ChemInform Abstract: Palladium‐Catalyzed Asymmetric Quaternary Stereocenter Formation.
Authors: Gottumukkala Aditya L. , Matcha Kiran , Lutz Martin , de Vries Johannes G. , Minnaard Adriaan J.
Published: September 2012

A variety of β,β‐disubstituted carbocyclic, heterocyclic, and acyclic enones undergo a conjugate addition of arylboronic acids in the presence of an optimized Pd(II)/Ag(I) catalyst.
ChemInform Abstract: Doubly Stereocontrolled Asymmetric Michael Addition of Acetylactone to Nitroolefins Promoted by an Isosteviol‐Derived Bifunctional Thiourea.
Authors: Ma Zhi‐wei , Liu Yu‐xia , Huo Li‐Juan , Gao Xiang , Tao Jing‐chao
Published: September 2012

A novel class of isosteviol‐derived bifunctional thiourea catalysts [cf.
ChemInform Abstract: anti‐Markovnikov Additions to N‐Allylic Derivatives Involving Ammonium—Carbenium Superelectrophiles.
Authors: Compain Guillaume , Martin‐Mingot Agnes , Frapper Gilles , Bachmann Christian , Houannetaud Marie‐Paule , Thibaudeau Sebastien
Published: September 2012

The work includes mechanistical studies, by means of deuterium labeling as well as DFT‐experiments.
ChemInform Abstract: Manganese Porphyrin Catalyzed Cycloisomerization of Enynes.
Authors: Ozawa Takuya , Kurahashi Takuya , Matsubara Seijiro
Published: September 2012

In the presence of manganese porphyrin, enynes of type (II), (V), and (VIII) undergo cycloisomerization.
ChemInform Abstract: An Intramolecular [2 + 2] Cycloaddition of Ketenimines via Palladium‐Catalyzed Rearrangements of N‐Allyl‐Ynamides.
Authors: DeKorver Kyle A. , Hsung Richard P. , Song Wang‐Ze , Wang Xiao‐Na , Walton Mary C.
Published: September 2012

Treatment of N‐allyl‐ynamides of type (I), (IV), (IX), and (XI) with Pd(PPh3)4 results in formation of bridged or fused bicycloimines depending on the alkene substitution.
ChemInform Abstract: Gold‐Catalyzed Isomerization of Unactivated Allenes into 1,3‐Dienes under Ambient Conditions.
Authors: Ting Chun‐Ming , Hsu Yi‐Ling , Liu Rai‐Shung
Published: September 2012

The isomerization of di‐, tri‐, and tetrasubstituted allenes into 1,3‐dienes is achieved in the presence of catalytic amounts of a AuCl3/nitrosobenzene system.
ChemInform Abstract: Ferritin‐Supported Palladium Nanoclusters: Selective Catalysts for Aerobic Oxidations in Water.
Authors: Kanbak‐Aksu S. , Hasan M. Nahid , Hagen W. R. , Hollmann F. , Sordi D. , Sheldon R. A. , Arends I. W. C. E.
Published: September 2012

The catalytic system is prepared from highly stable ferritin from the hyperthermophile Pyrococcus furiosus in high purity through a very simple procedure.
ChemInform Abstract: Chemoselective Halogenation of 2‐Hydroperfluoroalkyl Aldehydes.
Authors: Wiebe Donald A. , Burton Donald J.
Published: September 2012

Title compounds (II) are prepared via acid hydrolysis of readily accessible vinyl ethers (I).
ChemInform Abstract: Copper‐Catalyzed Direct Amination of Polyfluoroarenes and Azoles with Hydroxylamines and Its Application to the Synthesis of 3‐Aminobenzoheteroles.
Authors: Matsuda Naoki , Hirano Koji , Satoh Tetsuya , Miura Masahiro
Published: September 2012

The protocol allows the room temperature C—H amination with O‐acylated hydroxylamines.
ChemInform Abstract: Palladium‐Catalyzed Alkenylation and Alkynylation of ortho‐C(sp2)—H Bonds of Benzylamine Picolinamides.
Authors: Zhao Yingsheng , He Gang , Nack William A. , Chen Gong
Published: September 2012

A new and efficient method to prepare ortho‐alkenylated and ortho‐alkynylated benzylamines is reported.
ChemInform Abstract: Switching Regioselectivity in the Allylation of Imines by N‐Side Chain Tuning.
Authors: Delaye Pierre‐Olivier , Vasse Jean‐Luc , Szymoniak Jan
Published: September 2012

It is found that nitrogen side chain tuning can induce reversal of regioselectivity in addition of allylzincs to imines.
ChemInform Abstract: Acetylphosphonate as a Surrogate of Acetate or Acetamide in Organocatalyzed Enantioselective Aldol Reactions.
Authors: Guang Jie , Guo Qunsheng , Zhao John Cong‐Gui
Published: September 2012

It is found that the alkaloids (I) efficiently promote the asymmetric reaction of activated carbonyl compounds with the acetylphosphonates (III) and (IX).
ChemInform Abstract: Primary Amine, Thiourea‐Based Dual Catalysis Motif for Synthesis of Stereogenic, All‐Carbon Quaternary Center‐Containing Cycloalkanones.
Authors: Kang Jun Yong , Carter Rich G.
Published: September 2012

It is found that the thioureas (I) efficiently promote the regio‐ and stereoselective formation of α,α‐disubstituted cyclopentanones, cyclohexanones, tetrahydropyranones as well as tetrahydrothiopyranones from α‐substituted cycloalkanones.
ChemInform Abstract: Synthesis of Sterically Hindered Enamides via a Ti‐Mediated Condensation of Amides with Aldehydes and Ketones.
Authors: Genovino Julien , Lagu Bharat , Wang Yaping , Toure B. Barry
Published: September 2012

The reaction proceeds at room temperature and affords polysubstituted (E)‐enamides.
ChemInform Abstract: N,N‐Diarylammonium Pyrosulfate as a Highly Effective Reverse Micelle‐Type Catalyst for Hydrolysis of Esters.
Authors: Koshikari Yoshiki , Sakakura Akira , Ishihara Kazuaki
Published: September 2012

It is found that the pyrosulfate (APS) efficiently promotes the hydrolysis of a number of esters without loss of optical purity.
ChemInform Abstract: Boric Acid: A Highly Efficient Catalyst for Transamidation of Carboxamides with Amines.
Authors: Nguyen Thanh Binh , Sorres Jonathan , Tran Minh Quan , Ermolenko Ludmila , Al‐Mourabit Ali
Published: September 2012

Under these conditions a wide range of carboxamides can be prepared.
ChemInform Abstract: Access to C(sp3)—C(sp2) and C(sp2)—C(sp2) Bond Formation via Sequential Intermolecular Carbopalladation of Multiple Carbon—Carbon Bonds.
Authors: Wen Yanmei , Huang Liangbin , Jiang Huanfeng
Published: September 2012

Treatment of alkynes with benzyl chlorides and monosubstituted alkenes in the presence of Pd(OAc)2 provides a new, efficient, regio‐ and stereoselective approach to 4‐benzylated 1,3‐butadienes.
ChemInform Abstract: Dehydration of β‐Nitro Alcohols Catalyzed by Bu2SnO.
Authors: Veselovsky V. V. , Lozanova A. V.
Published: September 2012

A novel highly (E)‐selective dehydration of β‐nitro alcohols is catalyzed by dibutyltin oxide.
ChemInform Abstract: Consecutive Reactions of Dialkyl Ethynyl Carbinols with Acetylene in Superbase KOH/DMSO Suspension.
Authors: Schmidt Elena Yu. , Bidusenko Ivan A. , Zorina Nadezhda V. , Ushakov Igor A. , Mikhaleva Al'bina I. , Klyba Ludmila V. , Trofimov Boris A.
Published: September 2012

Reaction of the tertiary propargylic alcohol (I) with acetylene in the superbase KOH/DMSO gives the expected vinyl ether (III) along with dioxolane (IV) and vinylated acetylenic dimers (V) and (VI).
ChemInform Abstract: Palladium‐Catalyzed Alkylation of 1,4‐Dienes by C—H Activation.
Authors: Trost Barry M. , Hansmann Max M. , Thaisrivongs David A.
Published: September 2012

The title transformation is presented for the first time in the absence of a sulfoxide ligand.
ChemInform Abstract: Synthesis and Antimicrobial Activities of Structurally Novel S,S′‐Bis(heterosubstituted) Disulfides.
Authors: Ramaraju Praveen , Gergeres Danielle , Turos Edward , Dockey Sonja , Lim Daniel V. , Thomas John , Anderson Burt
Published: September 2012

A variety of novel title disulfides is synthesized and evaluated for antimicrobial cytostatic activity.
ChemInform Abstract: Enantioselective Synthesis of Nitrocyclopropanes via Conjugate Addition of Bromomalonate to Nitroalkenes Catalyzed by Ni(II) Complexes.
Authors: Lee Hyun Joo , Kim Sun Mi , Kim Dae Young
Published: September 2012

The air‐ and moisture‐stable chiral nickel complex (I) is successfully applied to the title reactions.
ChemInform Abstract: Synthesis of Trifluoromethyl‐Substituted Cyclopropanes via Sequential Kharasch—Dehalogenation Reactions.
Authors: Risse Julie , Fernandez‐Zumel Mariano A. , Cudre Yanouk , Severin Kay
Published: September 2012

It provides a new approach to trifluoromethylated cyclopropanes.
ChemInform Abstract: Three‐Component Assembly of Conjugated Enyne Scaffolds via E‐Selective Olefination of Ynals.
Authors: Cheng Dong , Ling Fei , Li Zexiang , Yao Weijun , Ma Cheng
Published: September 2012

Under these conditions a number of conjugated enynes are available.
ChemInform Abstract: Enantioselective Addition of Carbon Acids to α‐Nitroalkenes: The First Asymmetric Aminocatalytic Reaction in Liquefied Carbon Dioxide.
Authors: Nigmatov A. G. , Kuchurov I. V. , Siyutkin D. E. , Zlotin S. G.
Published: September 2012

The title reactions produce Michael adducts with enantioselectivities which are comparable to those obtained in organic solvents.
ChemInform Abstract: Enantioselective Ring‐Opening Reaction of Epoxides with MeOH Catalyzed by Homochiral Metal—Organic Framework.
Authors: Tanaka Koichi , Otani Ken‐ichi , Murase Takanori , Nishihote Shyota , Urbanczyk‐Lipkowska Zofia
Published: September 2012

Metal‐organic frameworks, obtained from BDA, Cu(NO3)2 and Ph‐NMe2, are applied as Lewis acid catalysts in the title reaction.
ChemInform Abstract: Mild Oxidation of Benzylic Amines into Aldehydes Using an Oxidative Polonovski‐Like Process.
Authors: Desjardins Samuel , Jacquemot Guillaume , Canesi Sylvain
Published: September 2012

Benzylic secondary and tertiary amines are oxidized to aldehydes with high‐valent iodine compounds.
ChemInform Abstract: Pd‐Catalyzed Domino Carbonylative—Decarboxylative Allylation: An Easy and Selective Monoallylation of Ketones.
Authors: Giboulot Steven , Liron Frederic , Prestat Guillame , Wahl Benoit , Sauthier Mathieu , Castanet Yves , Mortreux Andre , Poli Giovanni
Published: September 2012

To some extend, substituted allyl alcohols can be used as well.
ChemInform Abstract: Efficient Asymmetric Aldol Reaction Catalyzed by Polyvinylidene Chloride‐Supported Ionic Liquid/L‐Proline Catalyst System.
Authors: Zhang Xuan , Zhao Wenshan , Qu Chengke , Yang Lili , Cui Yuanchen
Published: September 2012

A novel PVC‐supported ionic liquid—L‐proline combined organocatalyst is successfully applied in the asymmetric aldol reaction of aromatic aldehydes with cyclic and acyclic ketones.
ChemInform Abstract: 2‐Iodoxybenzoic Acid‐Mediated Transformation of Halogenated Hydrocarbon in the Presence of Tetraethyl Ammonium Bromide.
Authors: Zhang Yuan , Han Jianlei , Xu Yanjun , Wei Yuping
Published: September 2012

The reagent can be easily recycled and reoxidized.
ChemInform Abstract: One‐Pot Synthesis of β‐Keto Esters and Preparation of 3‐Ketopalmitoyl‐CoA (IV).
Authors: Kosak Urban , Kovac Andreja , Gobec Stanislav
Published: September 2012

Base‐mediated reaction of ethyl acetoacetate with acyl chlorides provides β‐keto esters in low yields.
ChemInform Abstract: Sodium Methoxide: A Simple but Highly Efficient Catalyst for the Direct Amidation of Esters.
Authors: Ohshima Takashi , Hayashi Yukiko , Agura Kazushi , Fujii Yuka , Yoshiyama Asako , Mashima Kazushi
Published: September 2012

The first catalytic system for amide bond formation is presented by using a mild, nontoxic, environmentally benign, and convenient synthetic protocol.
ChemInform Abstract: Diacetoxyiodobenzene Mediated One‐Pot Synthesis of Diverse Carboxamides from Aldehydes.
Authors: Prasad Virendra , Kale Raju R. , Mishra Bhuwan B. , Kumar Dhananjay , Tiwari Vinod K.
Published: September 2012

It provides a new, facile, efficient, and widely applicable method to prepare carboxamides.
ChemInform Abstract: A Novel Oxidative Transformation of Alcohols to Nitriles: An Efficient Utility of Azides as a Nitrogen Source.
Authors: Rokade Balaji V. , Malekar Sanjeev K. , Prabhu Kandikere Ramaiah
Published: September 2012

The title method tolerates a variety of oxidizable functional groups and a few useful protecting groups.
ChemInform Abstract: Palladium‐Catalyzed Carbonylation of Aryl, Alkenyl, and Allyl Halides with Phenyl Formate.
Authors: Ueda Tsuyoshi , Konishi Hideyuki , Manabe Kei
Published: September 2012

It provides a mild and efficient method to prepare a wide range of phenyl esters.
ChemInform Abstract: Regioselective Synthesis of 6‐[Chloro(difluoro)methyl]salicylates by [3 + 3] Cyclocondensations of 1,3‐Bis(trimethylsilyloxy)buta‐1,3‐dienes with 1‐Chloro‐1,1‐difluoro‐4‐(trimethylsilyloxy)pent‐3‐en‐2‐one.
Authors: Erfle Silke , Reimann Sebastian , Bunescu Alina , Abilov Zharylkasyn A. , Spannenberg Anke , Langer Peter
Published: September 2012

The convenient new synthesis of the title compounds, which are not readily available by other methods, is reported.
ChemInform Abstract: Palladium‐Catalyzed Aminosulfonylation of Aryl‐, Alkenyl‐ and Heteroaryl Halides: Scope of the Three‐Component Synthesis of N‐Aminosulfonamides.
Authors: Emmett Edward J. , Richards‐Taylor Charlotte S. , Nguyen Bao , Garcia‐Rubia Alfonso , Hayter Barry R. , Willis Michael C.
Published: September 2012

For the first time the title reaction is possible by using an easy to handle and bench‐stable equivalent of sulfur dioxide, DABCO·2SO2.
ChemInform Abstract: Ag(I)‐Catalyzed Carbon—Carbon Bond Formation Between a Ketone and an Allylic C—H Bond.
Authors: Pati Kamalkishore , Liu Rai‐Shung
Published: September 2012

Mechanistic aspects are elucidated by deuterium labeling experiments, revealing that the cyclization proceeds via a prior isomerization to an external olefin, followed by a carbonyl‐ene reaction.
ChemInform Abstract: Copper‐Catalyzed Highly Selective Semihydrogenation of Non‐Polar Carbon—Carbon Multiple Bonds Using a Silane and an Alcohol.
Authors: Semba Kazuhiko , Fujihara Tetsuaki , Xu Tinghua , Terao Jun , Tsuji Yasushi
Published: September 2012

The optimized conditions are applied to a wide range of internal and terminal alkynes to provide the products with complete (Z)‐selectivity.
ChemInform Abstract: Syntheses of Polyfunctionalized Resveratrol Derivatives Using Wittig and Heck Protocols.
Authors: Chalal Malik , Vervandier‐Fasseur Dominique , Meunier Philippe , Cattey Helene , Hierso Jean‐Cyrille
Published: September 2012

In the modified Wittig reaction, Tms is used as a highly valuable protecting group of the phenolic functions of the starting arenes.
ChemInform Abstract: Aryl—Aryl Interactions as Directing Motifs in the Stereodivergent Iron‐Catalyzed Hydrosilylation of Internal Alkynes.
Authors: Belger Christian , Plietker Bernd
Published: September 2012

A well defined and active catalyst is used in the selective synthesis.
ChemInform Abstract: Asymmetric H—D Exchange Reactions of Fluorinated Aromatic Ketones.
Authors: Zhao Yujun , Lim Xiaozhi , Pan Yuanhang , Zong Lili , Feng Wei , Tan Choon‐Hong , Huang Kuo‐Wei
Published: September 2012

The first asymmetric H—D exchange is reported.
ChemInform Abstract: Tetrakis(acetonitrile)copper(I) Hexafluorophosphate‐Promoted Efficient Synthesis of Amidoalkyl Naphthols (IV) under Solvent‐Free Conditions
Authors: Soleimani Ebrahim , Zainali Mohsen
Published: September 2012

employing multicomponent condensation reactions
ChemInform Abstract: Synthesis of Fluorene Derivatives Through Rhodium‐Catalyzed Dehydrogenative Cyclization.
Authors: Morimoto Keisuke , Itoh Masaki , Hirano Koji , Satoh Tetsuya , Shibata Yu , Tanaka Ken , Miura Masahiro
Published: September 2012

The straightforward route to fluorenes involves the cleavage of 2 C—H bonds.
ChemInform Abstract: Catalytic Arylation of a C—H Bond in Pyridine and Related Six‐Membered N‐Heteroarenes Using Organozinc Reagents.
Authors: Hyodo Isao , Tobisu Mamoru , Chatani Naoto
Published: September 2012

Arylation of electron‐deficient N‐heteroarenes is achieved either with organozinc reagents through nickel catalysis or with arylboronic acids generating the active zinc reagent in situ.
ChemInform Abstract: Asymmetric Catalytic Epoxidation of α,β‐Unsaturated Carbonyl Compounds with Hydrogen Peroxide: Additive‐Free and Wide Substrate Scope.
Authors: Chu Yangyang , Liu Xiaohua , Li Wei , Hu Xiaolei , Lin Lili , Feng Xiaoming
Published: September 2012

The attractive, scalable, simple, mild, and environmentally‐benign title reaction is presented with a reusable, water and air‐tolerated catalytic system.
ChemInform Abstract: Prins Cyclization of Bis(silyl) Homoallylic Alcohols to Form 2,6‐cis‐Tetrahydropyrans Containing a Geometrically Defined Exocyclic Vinylsilane: Efficient Synthesis of Ring B of the Bryostatins.
Authors: Lu Ji , Song Zhenlei , Zhang Yuebao , Gan Zubao , Li Hongze
Published: September 2012

The cyclization shows excellent cis and (Z) selectivity to form tetrahydropyrans containing a geometrically defined exocyclic vinylsilane.
ChemInform Abstract: Synthesis of Halogenated α,β‐Unsaturated γ‐Butyrolactone Derivatives by Triphenylphosphine‐Catalyzed Cyclization of α‐Halogeno Ketones with Dialkyl Acetylenedicarboxylates (= Dialkyl But‐2‐ynedioates).
Authors: Asghari Sakineh , Habibi Ahmad Khabbazi
Published: September 2012

The presence of α‐halogen atoms is crucial to success of this cyclization reaction.
ChemInform Abstract: Enantioselective Bromolactonization of cis‐1,2‐Disubstituted Olefinic Acids Using an Amino‐Thiocarbamate Catalyst.
Authors: Tan Chong Kiat , Le Chancheng , Yeung Ying‐Yeung
Published: September 2012

In the case of derivatives (Ic) and (If), traces of the respective 6‐endo lactone are also obtained.
ChemInform Abstract: Manganese(III) Acetate Mediated Oxidative Radical Cyclizations. Toward Vicinal All‐Carbon Quaternary Stereocenters.
Authors: Logan Angus W. J. , Parker Jeremy S. , Hallside Michal S. , Burton Jonathan W.
Published: September 2012

Using this method a number of sterically congested [3.3.0]‐bicyclic γ‐lactones containing vicinal all‐carbon quaternary stereocenters can be prepared.
ChemInform Abstract: Copper‐Catalyzed Complete Regio‐ and Stereoselective Cyclization of 3‐Aryl‐1‐sulfanyl‐4‐oxahepta‐1,6‐diynes Triggered by Alkynylation.
Authors: Yoshimatsu Mitsuhiro , Sasaki Hitomi , Sugimoto Yuko , Nagase Yuya , Tanabe Genzoh , Muraoka Osamu
Published: September 2012

The title reaction allows a new, regio‐, and stereoselective access to 3,4‐dialkylidenefurans of type (III) and (VII).
ChemInform Abstract: Enantioselective Synthesis of α‐Alkylidene‐γ‐butyrolactones: Intramolecular Rauhut—Currier Reaction Promoted by Acid/Base Organocatalysts.
Authors: Takizawa Shinobu , Nguyen Tue Minh‐Nhat , Grossmann Andre , Enders Dieter , Sasai Hiroaki
Published: September 2012

An atom‐economical, chemo‐, diastereo‐, and enantioselective approach is presented.
ChemInform Abstract: Europium(III) Triflate‐Catalyzed Trofimov Synthesis of Polyfunctionalized Pyrroles.
Authors: Madabhushi Sridhar , Vangipuram Venkata Sairam , Mallu Kishore Kumar Reddy , Chinthala Narsaiah , Beeram China Ramanaiah
Published: September 2012

A variety of tri‐ and tetrasubstituted pyrrole derivatives is prepared.
ChemInform Abstract: Phosphine‐Catalyzed Intramolecular γ‐Umpolung Addition of α‐Aminoalkylallenic Esters: Facile Synthesis of 3‐Carbethoxy‐2‐alkyl‐3‐pyrrolines.
Authors: Andrews Ian P. , Blank Brian R. , Kwon Ohyun
Published: September 2012

The synthesis of the title compounds is the first example of this type of addition occurring via 5‐endo cyclization.
ChemInform Abstract: Asymmetric Cross Aldol Addition of Isatins with α,β‐Unsaturated Ketones Catalyzed by a Bifunctional Broensted Acid—Broensted Base Organocatalyst.
Authors: Liu Guo‐Gui , Zhao Hua , Lan Yu‐Bao , Wu Bin , Huang Xiao‐Fei , Chen Jian , Tao Jing‐Chao , Wang Xing‐Wang
Published: September 2012

Both enantiomers of 3‐hydroxyindolinone adducts can be prepared by using the two epimers RCI and SCI of a cinchona alkaloid derived thiourea.
ChemInform Abstract: An Organocatalytic Cascade Strategy for the Enantioselective Construction of Spirocyclopentane Bioxindoles Containing Three Contiguous Stereocenters and Two Spiro Quaternary Centers.
Authors: Sun Wangsheng , Zhu Gongming , Wu Chongyang , Hong Liang , Wang Rui
Published: September 2012

Chiral squaramide SQA efficiently catalyzes the title reaction of a methyleneindolinone with a (bromoethyl)indolinone to give the dispirocyclopentane compounds as mixtures of three diastereomers with up to 64% d.e.
ChemInform Abstract: Synthesis of 2‐Indol‐3‐ylbenzofulvenes Through a Tandem Reaction Catalyzed by Cationic Gold(I) Complexes.
Authors: Alvarez Estela , Miguel Delia , Garcia‐Garcia Patricia , Fernandez‐Rodriguez Manuel A. , Rodriguez Felix , Sanz Roberto
Published: September 2012

Gold‐catalyzed intramolecular transformation of propargylindoles provide benzofulvenes (II) and (III) via a tandem 1,2‐indole migration/aura‐iso‐Nazarov‐cyclization/elimination sequence.
ChemInform Abstract: Cu(II)‐Catalyzed C—H (SP3) Oxidation and C—N Cleavage: Base‐Switched Methylenation and Formylation Using Tetramethylethylenediamine as a Carbon Source.
Authors: Zhang Lei , Peng Chen , Zhao Dan , Wang Yue , Fu Hai‐Jian , Shen Qi , Li Jian‐Xin
Published: September 2012

If the starting material reacts sluggishly, the reaction can be conducted under reflux in DMA.
ChemInform Abstract: Synthesis of Indolines, Indoles, and Benzopyrrolizidinones from Simple Aryl Azides.
Authors: Brucelle Francois , Renaud Philippe
Published: September 2012

A mild and efficient method to prepare indolines, indoles, and benzopyrrolizidinones is reported.
ChemInform Abstract: Copper‐Catalyzed Arylation of o‐Bromoanilides: Highly Flexible Synthesis of Hexahydropyrroloindole Alkaloids.
Authors: Zhou Yongyun , Xi Yongkai , Zhao Jingfeng , Sheng Xianfu , Zhang Shuqin , Zhang Hongbin
Published: September 2012

Treatment of o‐bromoanilides bearing a tethered carbamate or sulfinamide group with LiN(Tms)2/ CuI allows a new access to 3,3‐disubstituted oxindole derivatives.
ChemInform Abstract: Organocatalyzed Enantioselective Formal [4 + 2] Cycloaddition of 2,3‐Disubstituted Indole and Methyl Vinyl Ketone.
Authors: Cai Quan , You Shu‐Li
Published: September 2012

The title reaction allows a new and efficient access to enantioenriched hexahydrocarbazoles and bridged ring indoline products.
ChemInform Abstract: Enantioselective Synthesis of Imidazolines with Quaternary Stereocenters by Organocatalytic Reaction of N‐(Heteroarenesulfonyl)imines with Isocyanoacetates
Authors: Nakamura Shuichi , Maeno Yuri , Ohara Mutsuyo , Yamamura Akiko , Funahashi Yasuhiro , Shibata Norio
Published: September 2012

An efficient and stereoselective method to prepare imidazolines bearing quaternary centers is reported.
ChemInform Abstract: N‐Heterocyclic Carbene (NHC) Catalyzed Cycloaddition of CO2 to N‐Tosyl Aziridines: Regio‐ and Stereoselective Synthesis of Oxazolidine‐2‐ones.
Authors: Seayad Jayasree , Seayad Abdul Majeed , Ng Joseph Kok Peng , Chai Christina Li Lin
Published: September 2012

An efficient synthesis of di‐ and trisubstituted oxazolidinones is described by IPrCl‐catalyzed carboxylation of N‐tosyl aziridines (I) and (V) with carbon dioxide.
ChemInform Abstract: Gold Catalysis: One‐Pot Alkylideneoxazoline Synthesis/Alder‐Ene Reaction.
Authors: Hashmi A. Stephen K. , Littmann Anna
Published: September 2012

The reaction of N‐propargylamides (I) and azodicarboxylates (II) provides functionalized oxazoles (III) in high yields through a five‐step cycloisomerization/Alder‐ene reaction pathway.
ChemInform Abstract: Pd(II)‐Catalyzed ortho Arylation of 2‐Arylbenzothiazoles with Aryl Iodides via Benzothiazole‐Directed C—H Activation.
Authors: Ding Qiuping , Ji Huafang , Wang Dan , Lin Yuqing , Yu Weihua , Peng Yiyuan
Published: September 2012

A novel, regioselective and efficient method for the synthesis of the compounds (III) and (V) is described.
ChemInform Abstract: Traceless Tosyhydrazone‐Based Triazole Formation: A Metal‐Free Alternative to Strain‐Promoted Azide—Alkyne Cycloaddition.
Authors: van Berkel Sander S. , Brauch Sebastian , Gabriel Lars , Henze Michael , Stark Sebastian , Vasilev Dimitar , Wessjohann Ludger A. , Abbas Muhammad , Westermann Bernhard
Published: September 2012

The Sakai reaction as an alternative strategy for metal‐free triazole formation is presented.
ChemInform Abstract: Stereo‐ and Regio‐Selective One‐Pot Synthesis of Triazole‐Based Unnatural Amino Acids and β‐Amino Triazoles.
Authors: Baig R. B. Nasir , Varma Rajender S.
Published: September 2012

The reaction has a broad substrate scope and is conducted under environmentally benign conditions.
ChemInform Abstract: Synthesis of a New Series of Oxadiazoles and Triazoles as Antimicrobial Agents.
Authors: Rastogi Nisheeth , Kant Padam , Sethi Rakesh , Shukla Sarveshwar , Tripathi Diwakar
Published: September 2012

Novel 2‐thioxooxadiazoles and ‐triazoles as well as their S‐ or N‐substituted analogues are prepared and tested for their antifungal and antibacterial potency.
ChemInform Abstract: Synthesis and Antimicrobial Activity of Some New Lactosylated‐1,2,4‐dithiazolidine (Hydrochlorides).
Authors: Deshmukh S. K. , Agrawal P. T. , Deshmukh S. P.
Published: September 2012

All 1,2,4‐dithiazolidines are screened for both antibacterial and antifungal activity.
ChemInform Abstract: Synthesis of cis‐2,6‐Tetrahydropyran‐4‐one via Diastereoselectively Intramolecular Cyclization of β‐Hydroxy Allyl Ketone.
Authors: Lee Adam Shih‐Yuan , Lin Li‐Shin , Chang Yu‐Ting
Published: September 2012

Hydroxy allyl ketones (III) are prepared without protection of the hydroxy group under Barbier‐type conditions.
ChemInform Abstract: Basic Ionic Liquid‐Catalyzed One‐Pot Synthesis of the Spiroacenaphthylene Derivatives in Water Medium.
Authors: Zheng Jia , Li Yiqun
Published: September 2012

Various spiroacenaphthylene derivatives are obtained under mild conditions in an efficient one‐pot multicomponent reaction using a reusable basic ionic liquid as catalyst.
ChemInform Abstract: An Efficient Copper‐Catalyzed Three‐Component Synthesis of 3‐C‐Linked Glycosyl Iminocoumarins.
Authors: Palanichamy Kalanidhi , Suravarapu Sankar R. , Kaliappan Krishna P.
Published: September 2012

The reaction provides a general strategy for the synthesis of previously unknown title compounds as antibiotic analogues.
ChemInform Abstract: Synthesis of 3‐Substituted Isocoumarin Derivatives via CuI‐Catalyzed Reaction of o‐Bromobenzamides with 1,3‐Diketones.
Authors: Cai Shangjun , Wang Fei , Xi Chanjuan
Published: September 2012

Optimized conditions which need neither an additive nor a ligand are developed for the preparation of the important heterocyclic scaffolds.
ChemInform Abstract: Ytterbium Perfluorooctanoate [Yb(PFO)3]: A Novel and Efficient Catalyst for the Synthesis of Tetrahydrobenzo[a]xanthene‐11‐ones under Microwave Irradiation.
Authors: Sundar Chereddy Syama , Rao Kunda Uma Maheswara , Reddy Nemallapudi Bakthavatchala , Reddy Mudumala Veera Narayama , Prasad Sthanikam Siva , Reddy Cirandur Suresh
Published: September 2012

A novel and rapid method for the synthesis of the title compounds is reported by using a reusable catalyst.
ChemInform Abstract: DPTA‐Catalyzed One‐Pot Regioselective Synthesis of Polysubstituted Pyridines and 1,4‐Dihydropyridines.
Authors: Li Jianjun , He Ping , Yu Chuanming
Published: September 2012

Advantages of the protocol include excellent yields, environmentally benign source of nitrogen, and mild conditions.
ChemInform Abstract: An Efficient One‐Pot Synthesis of 1,4‐Disubstituted 3‐Amino‐2‐pyridone Derivatives via Three‐Component Reactions of Alkynyl Aldehydes and Amines with Ethyl 2‐((Diphenylmethylene)amino)acetate.
Authors: Zhou Qingfa , Chu Xueping , Tang Weifang , Lu Tao
Published: September 2012

A mild, room temperature, one‐pot route to diverse 1,4‐disubstituted pyridone derivatives is described.
ChemInform Abstract: [Ru(bpy)3]2+ Aided Photocatalytic Synthesis of 2‐Arylpyridines via Hantzsch Reaction under Visible Irradiation and Oxygen Atmosphere.
Authors: Ananthakrishnan Rajakumar , Gazi Sarifuddin
Published: September 2012

A simple and green synthesis of the compounds (III) is developed.