bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal time for adjuvant therapy initiation in breast cancer patients: A single center experience
Authors: Vranjkovic Bojana , Petrovic Dragana , Radic Jelena , Popovic Maja , Bjelobrk Kolarov , Petrovic Nemanja
Published: March 2019

Introduction. This retrospective study evaluates the association between the
time of chemotherapy initiation and disease free survival in regard to
breast cancer subtypes and stage at diagnosis. Material and Methods. The
study included a total of 1075 breast cancer patients, stages I - III,
treated at Oncology Institute of Vojvodina, Serbia (from 2010 to 2012; n =
617). The gathered data included prognostic factors used in everyday
practice. Patients were divided into three groups according to the interval
between surgery and chemotherapy (? 30, 31 - 60, ? 61 days). Disease free
survival was calculated. Results. Among the 617 patients, the 5-year disease
free survival estimate was similar: 81.5%, 81.0%, 84.6% (log-rank test, p =
0.728) regarding the time of adjuvant chemotherapy initiation: ? 30 days, 31
- 60, and ? 61 days, respectively. The study showed that 85% of our breast
cancer patients started adjuvant chemotherapy within 3 months after
definitive surgery. In multivariate analysis, independent prognostic factors
for disease free survival were nodal status and tumor size. The 5-year
disease free survival estimate was 85.8% (p = 0.001) for patients with
luminal- A subtype (Estrogen +, Progesterone high, human epidermal growth
factor receptor 2-, Ki-67 < 20%) with a median follow-up of 62,7 months;
for patients with luminal-B (Luminal B (human epidermal growth factor
receptor 2 -) Estrogen +, human epidermal growth factor receptor 2-,
either Ki-67 high or Progesterone low, Luminal B (human epidermal growth
factor receptor +) Estrogen +, human epidermal growth factor receptor 2 +,
any Ki-67, any Progesterone) 78.3% (p = 0.534) with a median follow-up of
55.9 months; for patients with triple negative breast cancer it was 73.4%
with a median follow-up of 58,1 months, and for patients with human
epidermal growth factor receptor 2+ it was 77.1% (p = 0.448) with a median
follow-up of 55.5 months. Conclusion. Early initiation of adjuvant
chemotherapy is particularly important in patients with advanced- stage
breast cancer at diagnosis, and those with trastuzumab- treated
triple-negative breast cancer and human epidermal growth factor receptor
2-positive tumors.
PENGARUH SELF-HYPNOSIS TERHADAP INTENSITAS NYERI DAN TINGKAT KECEMASAN LANSIA PENDERITA OSTEOARTRITIS
Authors: Irawan Chandra , Sudiyanto Aris , Fanani Mohammad
Published: March 2019

Arthritis or rheumatism in the elderly (called osteoarthritis) is chronic and can not be recovered. Pain becomes the main symptoms of osteoarthritis joints experience. The pain can disrupt motor function, sleep disorders and psychological stress. Nowadays, the treatment for elderly with osteoarthritis pain therapy is to pharmacotherapy. Due to psychological disorders such as anxiety and depression play a role in the recurrence of pain, then there is a complementary therapy intervention that is self-hypnosis. Self-hypnosis (as a complementary therapy) popular and familiar because it is easy to do, inexpensive and can be done at home independently. The aimed of this study was to find out whether there is any influence of self-hypnosis on the pain intensity and level of anxiety elderly with osteoarthritis.This study was a quantitative research in the form of quasi experimental randomized pretest-posttest control group design, intervention module using self-hypnosis to reduce pain intensity and level of anxiety elderly with osteoarthritis. This study was approved by the hospital ethics committee. The result of this study was a significant difference in the value pretest and posttest group treated osteoarthritis pain and anxiety elderly. The mean value of NRS (pain) treatment group pretest posttest 1,47 ± 0.57 and 0.97 ± 0.72 with p = 0.001> 0.05. The mean value of TMAS (anxiety) treatment group pretest amounted to 13.13 ± 2.27 posttest 10.93 ± 3.35 with p= 0.000Keywords: Self-Hypnosis, Pain Intensity, Level Of Anxiety, The Elderly With Osteoarthritis.
Tulevaisuuden yhdistetyt terveysteknologia mahdollisuudet ensihoidon ei kiireellisten tehtävien hoitamisessa
Authors: Hautala Mia , Ervasti Mari , Pikkarainen Minna , Reponen Jarmo , Daavittila Iita , Raatiniemi Lasse , Martikainen Matti , Tuukkanen Johanna , Korpelainen Juha
Published: March 2019

Ensihoitopalvelujen tarve kasvaa sosiaali- ja terveydenhuollon palvelurakenteessa tapahtuvien uudistusten sekä väestön ikääntymisen myötä. Uusimmat teknologia- ja analytiikkaratkaisut auttavat palveluiden uudelleen organisoimisessa ja hoitopolkujen kehittämisessä. Tässä tutkimuksessa tarkastellaan tulevaisuuden yhdistettyjen terveys teknologioiden mahdollisuuksia pohjautuen asiantuntija työpajoihin liittyen ei-kiireellisiin ensihoidon tehtäviin. Tapauksen nykytilanne ja tulevaisuuden hoitopolut kuvattiin ja analysoitiin yhdessä terveysalan asiantuntijoiden, teknologiatoimittajien, tutkijoiden ja potilasnäkökulman edustajien kanssa. Kuvattu potilastapaus keskittyi kotisairaanhoidon piirissä olevaan ikääntyneeseen henkilöön, joka kärsii toistuvista virtsatieinfektioista. Tutkimuksen tuloksena löydettiin mm., että potilas tapauksiin liittyviä hoitopolkuja voidaan parantaa tukemalla hätätilanteen tunnistamista, lisäämällä terveystietämystä ja kehittämällä ratkaisuja, jotka mahdollistavat ensi- ja lääkehoidon nopeamman aloituksen sekä tehokkaamman yhteistyön potilaan, kotisairaanhoidon, sairaalan ja ensihoidon välillä. Lisäksi havaittiin, että tulevaisuudessa etämittarit mahdollistavat kotimittaustulosten nopeamman hyödyntämisen ja uusien teknologiaratkaisujen myötä tietoa on paremmin saatavilla.
Uji Ketahanan Luntur dan Karakterisasi Serbuk Tinta Cumi-Cumi (Loligo sp.) sebagai Dasar Pewarna Hitam untuk Kain Tenun Ikat Asal Nusa Tenggara Timur
Authors: Nitsae Merpiseldin , Mellissa E. S. Ledo Egertha Karpada Arsun Banamtuan , Alan Ch. Sabuna Ronny S. Mauboy
Published: March 2019

Penelitian ini bertujuan untuk menguji sifat karakter dan karakteristik bubuk tinta cumi. Uji ketahanan luntur menggunakan metode Grey Scale dan Staining Scale, sedangkan uji karakteristik tinta cumi-cumi menggunakan metode FT-IR dan SEM. Hasil yang diperoleh menunjukkan pada saat kain katun dicelupkan ke dalam 250 mL tinta cumi-cumi selama 1 jam menghasilkan warna hitam namun mudah luntur sehingga warna yang dihasilkan perlu dipertahankan menggunakan fiksator yaitu kapur tohor dan tawas. Variasi konsentrasi fiksator yang digunakan yaitu: 20, 50, dan 100 g/mL. Hasil yang diperoleh menunjukkan bahwa fiksator kapur tohor menghasilkan warna cokelat, sedangkan fiksator tawas menghasilkan warna hitam pekat. Hasil uji menggunakan Grey Scale dan Staining Scale menunjukkan perlakuan terbaik pada konsentrasi fiksator 100 g/mL. Selain itu hasil karakterisasi tinta cumi-cumi menggunakan FT-IR menunjukkan adanya serapan pada peak 3236, 33 cm-1 merupakan gugus –OH dan gugus –NH (tumpang tindih); 2964, 39 cm-1 dan 2927, 74 cm-1 merupakan gugus C-H sp2; 1633, 59 cm-1 dan 1544, 88 cm-1 merupakan ikatan cincin aromatik dari C=C dan C=N. Hasil karakterisasi menggunakan SEM menunjukkan diameter serbuk bervariasi yaitu berukuran 58, 8 µm; 68, 3 µm; dan 68, 8 µm yang tidak teratur (serpihan amorf).
Optimalisasi Gula Cair dan pH Medium untuk Fermentasi Alkohol dari Jus Curucuma xanthorihiza
Authors: Atmodjo Kianto
Published: March 2019

Gula cair suatu produk baru dari gula yang tersusun dari fruktosa, glukosa dan disakarida dianggap lebih baik daripada gula kristal. Penelitian ini bertujuan untuk mengetahui konsentrasi gula cair dan pH medium yang digunakan dalam fermentasi sari temulawak (Curcuma xantorhiza Raoxb) oleh Saccharomyces cerevisiae untuk memproduksi alkohol.  Satu kg temulawak kering dihancurkan ditambah air sebanyak 8 liter, ditambahkan 250 g kecambah kacang hijau, direbus selama 30 menit, lalu didinginkan kemudian direbus lagi tiga kali rebusan disaring lalu diambil airnya kemudian dimasukkan ke dalam botol fermentasi sebanyak 300 ml kemudian ditambahkan gula cair sehingga diperoleh variasi 0,15%, 30%, 45%, 60% dan 75%. Medium sari temulawak ini diatur pH nya menjadi 4, 4,5, 5,0, 5,5 dan 6. Selanjutnya 1 g bibit S. cerevisiae ditambahkan pada tiap botol fermentasi lalu ditutup. Fermentasi berlangsung pada suhu kamar. Parameter penelitian berupa total sel, pH dan gula reduksi yang diukur tiap sehari sebanyak tiga kali, dan kadar alkohol setelah satu bulan fermentasi.  Hasil menunjukkan tidak adanya hubungan yang signifikan antara peningkatan kadar gula dan perbedaan pH medium terhadap total sel, perubahan pH dan kadar gula. Namun ada hubungan yang nyata  antara kenaikan kadar gula medium dengan alkohol yang dihasilkan. Efisiensi konversi gula menjadi alkohol tertinggi  di atas 3% terjadi pada fermentasi pada  konsentrasi gula 45%. Kadar alkohol tertinggi dihasilkan pada pH medium awal 5.
EFFECTIVITY TEST ANTIBACTERIAL SENGGANI LEAF (Melastoma candidum) ON BACTERY Streptococcus mutans
Authors: Gloria Yelin , Delfina Dini , Bachtiar Yulitas
Published: March 2019

Senggani leaves are one of the highland plants in Indonesia with the latin name Melastoma candidum. The results of phyitochemical screening that have been carried out show that senggani leaves contain tannin and flavonoid hich have an antibacterial function by inhibiting bacterial action in cell formation and even growth. The survey metode used is descriptive (for explanation of plants) and experimental (for an explanation of antibacterial test). In the bacterial test using a concentration of leaf extract of 6,25%, 12,5%, 25%, 50%, 75% and 100%. An placebo as positive control (+) and DMSO as a negative control (-). Antibacterial to streptococcus mutans (gram-positive bacteria) which at concentration of 6,25% has an average 12 mm, 12,5% has an average 13,56 mm, 25% has an average 15,30 mm, 50% on average 17,20 mm, 75% on average 18,10 mm and 100% have an average of 19,06 mm. So, senggani leaves have effect antibacterial to Streptoccous mutans.
Construction staff of Moscow in 1918-1921
Authors:   Moscow State University of Civil Engineering  (National Research University, Panteleeva Tatyana Leonidovna
Published: March 2019

The paper deals with the situation of construction workers and professionals in the overlooked historical period of military communism characterized by a combination of pre-revolutionary and ideologically motivated approaches to staff relations. Due to the development of daily occurrence history, extending the range of sources and gathering new facts have considerable relevance today. Based on the unpublished documents of the Moscow Committee of State Structures, the study considers the status of Moscow construction staff in 1918-1921 and evaluates the preservation and information content of archival sources. The principles of historicism and objectivity are employed along with the problem-based approach basing upon archives and relevant literature. The study identifies data that can be used in further research. The authors concluded that cash payments remained an important component of remuneration in the period of military communism. Joint procurement of goods and their distribution by workers and employees were commonly available as well.
The problem of providing South Ural villagers with consumer goods (the late 1930s – the early 1940s)
Authors:   Southern Ural State University of  Humanities and Education Science, Korshunova Nadezhda Vladimirovna , Nagimova Alevtina Olegovna ,   Southern Ural State University of  Humanities and Education Science
Published: March 2019

The research analyzed the availability of manufactured goods and food for South Ural villagers by a case study of Chebarkulsky District from 1936 to early 1941. This was the period of free trade because the consumer goods were sold on cash rather than card system basis. The paper presented a wide range of goods revealed during the audit with the help of the contemporaneous archives and newspapers. Nevertheless, journalists of local print media noted the shortage of a number of goods, particularly manufactured ones, as well as furniture. Despite the centralized supply, hunting and fishing continued to play a big role in rural areas that helped vary people’s diets. Poor food production management was one of the reasons for failure to supply the population with dairy products. Notwithstanding the difficulties, villagers were sufficiently provided with essentials.
The phenomenon of alimentary culture: a conceptual analysis
Authors:   Astrakhan State University, Palatkin Vladimir Vladimirovich
Published: March 2019

The research notes that the regulation of food production and consumption among different ethnic groups and denominations has always been an important component of their common culture. Differentiation could occur depending on gender, status, social, age, seasonal, and geographical characteristics. Since ancient times, humankind has created a food culture environment. It fits into the culture system in special ways, the so-called cultural codes. Cooking and food serving technologies go beyond the private profession and become a public action as a part of festivals, symposia, and exhibitions of culinary arts competitions. There is a growing demand for gastronomic tourism which not only introduces the cuisine of different geographic zones and ethnic groups but also contributes to their distribution. All this suggests that food is regarded as both a way to meet biological needs and a cultural phenomenon. The study analyzes the concepts relevant to food production and consumption and substantiates the benefits of the term ‘alimentary culture’.
Secondary education in the educational culture of the Russian Empire in the 19th century
Authors:   Herzen State Pedagogical University of Russia, Obukhovich Vladimir Vladimirovich
Published: March 2019

The paper deals with secondary education in the Russian Empire of the 19th century that has always been an essential part of the culture of the country. The relevance of the study is determined by the importance of the imperial period for the development of Russian science and education. The research discusses the establishment of the secondary education system in the Russian Empire. In the 18th-19th centuries, the development of this system was an indispensable element of cultural evolution driven by many complex social factors and challenges of the era. By the middle of the 19th century, gymnasium teachers could be characterized as a stable social and professional group with their social niche and social status. The research investigates the legislative and sociocultural frameworks of the era as well.
The aspects of studying tea culture in China
Authors:   Heilongjiang International University (PRC), Zhou Xiaowei
Published: March 2019

The research defines the approaches and methods employed to investigate Chinese tea culture. A sociocultural approach is regarded as the main one in the study of everyday culture. The paper analyzes the works of modern Chinese scientists such as Lu Yu, Guo Menlyan, Zhang Zhongliang, Mao Xianpo and others. The author proved that the early tea culture was of interest to Chinese thinkers who revealed its relationship with religion and religious adherents, assessed the effects of tea on human health, and analyzed the development of tea drinking ritual. The study identifies the meaning of tea culture, its characteristics and role in sociocultural communication in general works. Researchers emphasize that tea culture reflects the Chinese mentality, the spiritual life of people, in particular the idea of harmonious coexistence, team spirit, and unity. The further research in this regard implies the comprehensive consideration of the phenomenon of tea culture, its evolution, the sociocultural factors of its existence and development.
War as an anthropological phenomenon: prohibition and the violation of the prohibition
Authors:   Vladivostok State University of  Economics and Service, Kirsanova Lidia Ignatyevna , Korotina Olga Aleksandrovna ,   Far Eastern Federal University
Published: March 2019

Based on scientific literature and fiction, an attempt is made to substantiate the phenomenon of war from the anthropological perspective, reveal the essence, limits, and risks of transgressive experience, identify the qualities of a sovereign subject. While analyzing and understanding this phenomenon in the context of the prohibition, the authors present their view on relevant issues and draw reasoned conclusions. In particular, an anthropological subject objectifies its existence in the forms of excessiveness, transgressive experience reflected in “weak” forms of wastefulness (obsession with luxuries and money) and “strong” dimensions (piracy, terrorism, war). War as the experience of the absolute sovereign subject cannot be realized and transferred through philosophical categories, theories, and concepts. If the ontology and gnoseology of war are hampered, it is necessary to rely on the anthropology of the subject of sacrifice, self-sacrifice, murder, and war. The latter relates to the ban and its breach, aims to make a human sacrifice, sacralize murder, delete the views from the experience of profane sacrifice defining the conditions for the existence of a sovereign subject. The subject of absolute sovereignty constitutes the experience of the pre-predicative givenness of consciousness that is closed to the subject itself and the universal subject and reflects human philosopher. Elusiveness, fragmentation, and uncertainty of the pre-predicative experience of war have made it necessary to rely on analytics of unfinished, open-ended texts such as memoirs, diaries, prose, poetry, and cinema.
County publications of 1917 (Borisoglebsk newspapers in the Russian State Library and the State Public Historical Library)
Authors: Murashev Arkady Anatolyevich ,   Moscow State University of Civil Engineering  (National Research University
Published: March 2019

There has been little historical research on the development of printed periodicals in Tambov region in 1917. In Moscow libraries (the Russian State Library and the State Public Historical Library), the following regional newspapers have been found: Borisoglebskoe Ekho, Borisoglebskie Izvestia, Rodnoy Kray, Golos Truda, Respublikanets, Borisoglebsky Vestnik, Borisoglebskaya Zhizn, and Fakel. The research determines the first and final dates of issues and the completeness of each newspaper. The study describes the development of county publications in 1917. After the February Revolution, the increasing number of publications resulted from both the lack of publishing constraints and the unprecedented hunger for information among the population. The study identifies the newspaper (Borisoglebskaya Zhizn) that published the articles of the outstanding writer Prince S.M. Wolkonsky based on the mention of this in his memoirs. The information capacity of Borisoglebsk newspapers with different political content, i.e. editorials, letters, chronicles, newspaper headlines, announcements, allows one to present the diverse and vast characteristics of various aspects of life in Borisoglebsk and the eponymous county in 1917.
Electrical Resistivity and Flexural Strength of Plastic Composites Reinforced with Pineapple Leaf Particles
Authors: Abu Kassim Masitah , Bahari Shahril Anuar , Yahya Mohd Khairi , Muhammad Khairul Safuan , Baharom Rahimi
Published: March 2019

The electrical resistivity and flexural strength of plastic composites reinforced with pineapple leaf particles (PCPLP) is presented. PCPLP were produced using different plastic materials; Polyethylene (PE) and Polypropylene (PP), and different plastic-pineapple leaf particle ratios; 50:50 and 70:30. The PCPLP were tested and evaluated with respect to electrical resistivity and flexural strength according to ASTM D257 and D790, respectively. The results indicate that PCPLP made from PP exhibits better electrical resistance than PE, which may be attributed to the better frequency insulation behaviour of PP. PCPLP using the higher ratio of 70:30 also exhibited better electrical resistance than the lower 50:50 ratio. Cellulose materials inherently influence the electrical resistance of plastic composites, due to their natural propensity to absorb moisture. The PCPLP produced using a ratio of 50:50 for both PP and PE composites exhibited better MOE results than the 70:30 composites, however the converse is true with respect to the MOR. MOE of PCPLP was increased with increasing pineapple leaf particles content due to the greater matrix stiffness of this natural particle with respect to plastic matrix. However, high percentage of filler particles in the matrix (70:30 ratio) has reduced the toughness in the composite structure due to the lost of physical contact between high accumulated particles.
PARA HARIMAU YANG MENOLAK PUNAH: ESTETIKA DOKUMENTER TELEVISI DI ERA PASCAREFORMASI
Authors: Rozi Romdhi Fatkhur , Hasan Renta Vulkanita
Published: March 2019

ABSTRAKPara Harimau Yang Menolak Punah(Imanda Dea Sabiella dan Edho Cahya Kusuma, 2013) merupakan judul dokumenter televisi produksi Eagle Institutedengan ciri filmis berupa paduan antara gambar dan tuturan (wawancara). Dokumenter ini merupakan objek material yang menarik untuk diteliti dalam konteks kontinuitas dan perubahan estetika, selama era pasca reformasi dengan zaman Orde Baru sebagai pembanding. Jika pada masa orde baru, kampanye pelestarian lingkungan melalui media dokumenter notabene diproduksi oleh pemerintah melalui estetika sinematik yang bersifat propagandis, maka saat ini dokumenter produksi Eagle Institutejustru menggunakan estetika sinematik yang kritis sebagai konter bagi pemerintah. Fakta dan fiksi (faksi) menjadi istilah yang digunakan dalam penelitian ini sebagai bentuk kontinuitas dan perubahan dokumenter televisi Indonesia. Alasan pemilihan istilah ini adalah dunia fenomenal dalam banyak kasus, seperti yang terlihat dalam dokumenter, seakan berbeda dari "dunia nyata", meskipun dalam kenyataannya rekaman itu berasal dari “dunia nyata/realitas”. Penelitian ini menggunakan pendekatan film kognitif untuk mengamati sejauh mana Faksi beroperasi sebagai media kritik yang secara estetis merangkai dokumenter tersebut. Struktur mental digunakan untuk menjelaskan Faksi melalui petunjuk filmis hingga diperoleh kesimpulan tentang kritik yang ingin disampaikan melalui dokumenter. ABSTRACTPara Harimau Yang Menolak Punah (Imanda Dea Sabiella dan Edho Cahya Kusuma, 2013) is the title of a television documentary produced by Eagle Institute. The documentary has characters that specifically contains of expository shots. This documentary is an interesting material object to be examined in the context of continuity and aesthetic change, during the post-reform era with the New Order era as a comparison. During the new order era, environmental conservation campaigns through documentary media were produced by the government through propagandist cinematic aesthetics. Whereas, the post-reform documentary produced by Eagle Institute actually uses a critical cinematic aesthetic as a counter for the government. Fact and fiction (faction) became the term used in this study as a form of continuity and change of Indonesia documentary. The reason for choosing this term is the phenomenal world in many cases, as seen in the documentary, as though it were different from the "real world", even though in reality it came from "the real world". This study uses a cognitive film approach to observe the extent to which the Faction operates as a criticism medium which aesthetically assembles the documentary. The mental structure is used to explain the Faction through filmic clues to the conclusion of the criticism that the documentary wishes to convey.
KONSEP SLAMMING PADA ANATOMI HURUF DAN TIPOGRAFI BAND REZUME
Authors: Setiasih Ni Wayan
Published: March 2019

Huruf adalah hal yang terpenting dalam kehidupan sehari-hari, karena huruf manusia dapat berkomunikasi. Huruf menentukan berhasil tidaknya suatu penerima dan pengirim pesan. Permasalahan yang nantinya akan dibahas adalah konsep yang digunakan pada huruf dan tipografi pada band metal yang memiliki sub genre Slamming. Band yang memiliki aliran musik Brutal Slamming Death Metal, mengusung konsep dalam pembuatan huruf dan tipografi sesuai dengan aliran music yang digelutinya yakni Slamming. Huruf dan tipografi dari band Rezume adalah penggambaran dari jenis musik slamming. Tipografi yang yang memiliki kesan sulit dibaca karena memiliki tingkat distorsi sehingga tipografi ini unik untuk dikaji berdasarkan perspektif seni.Dalam penelitian ini materi yang digunakan adalah tipografi pada band Rezume sebagai objek yang akan diangkat sebagai kasus. Permasalahan yang diangkat yaitu, bagaimana peran konsep slamming pada bentuk anatomi huruf dan tipografi band Rezume? dan adapun tujuan dari penulisan hasil penelitian ini adalah untuk mengetahui peran konsep slamming pada bentuk anatomi huruf dan tipografi band Rezume.Materi yang digunakan dalam mengkaji konsep pada anatomi huruf dan tipografi band Rezume adalah teori anatomi huruf dan kaitannya terhadap konsep. Metode yang digunakan dalam artikel ini adalah metode deskritif kualitatif yakni menguraikan secara fakta mengenai peran konsep slamming pada anatomi huruf dan tipografi band Rezume.
Effect of Different Seed Water Content and Storage Duration towards Seed Viability of Local Genotype Brown Rice Daro Merah
Authors: Dwipa Indra , Muhsanati Muhsanati
Published: March 2019

Most of rice seeds experience after ripening problem which then result in seed dormancy. This kind of dormancy could be broken through various types of treatments, including storaging in dry place for certain period. This study was aimed to evaluate the combination between seed water content and storage duration to induce the seed germination of local genotype brown rice, Daro Merah. Various levels of seed water content (6-10, 11-15, 16-20 and 21-25 %) and storage duration (2, 4, 6 and 8 weeks) were evaluated to identify its effect on Daro Merah seed germination. Data were analyzed using two-way analysis of variance where significance were further proceeded using Duncan’s New Multiple Range Test with a p>0.05. The results showed that seed germination of Daro Merah reached 95 % at five days after seeding when the seed water content was maintained at 6-10% and stored for 8 weeks. After 14 days, the germination reached 99 % and most of the seeds showed some shoots emerged from the soil.

Keywords: Brown rice, germination, seed water content, storage duration, Daro Merah
The Effect of Pollination Models on Yield of Red Pitaya (Hylocereus polyrhizus)
Authors: Renfiyeni Renfiyeni
Published: March 2019

Red pitaya is getting more popular in Indonesia recently as one of high antioxidant sources with a promising economic value. However, the production of this CAM plant is restricted by low success percentage of its natural pollination and self incompatibility problems. Therefore, artificial pollination is required to overcome these problems and increase its yield. This study was aimed to evaluate the effect of pollination models towards the yield of red pitaya. This study was conducted using randomized block design with three pollination models applied into nine groups. Pollination models used were open pollination (P1), hand-self-pollination (P2) and hand-cross pollination (P3). Several floral-related parameters, including the elongation of flower bud, diameter of blooming flower, length of stigma, number and length of anthers, were assessed. Effect of different pollination models was also observed through some yield-related parameters, such as fruit weight, fruit diameter, fruit length, harvesting age and number of fruit sets. This study revealed that hand cross pollination produced the best yield performance showing 541.1 gram of fruit with 11.5 in length and 8.66 cm in diameter. Harvesting age and number of fruit sets showed no significant difference among those three pollination models.   

Keywords: Pollination, red pitaya, yields, fruits, flowers
Isolation of Cellulose Degradation Bacteria (CDB) from acid soil as a potential candidate of organic waste degradation
Authors: Samah Eri
Published: March 2019

Background: The study aimed to obtain CDB with high degraded activities, determined growth curve, protein content, and cellulase maximum activity (exoglucanase and endoglucanase). Method:  The cellulose activity calculated according to Miller (1959), protein content was measured by Bradford method with bovine serum albumin (BSA) as a standardize protein. Result: Six isolates of CDB were found as potential degradation of organic waste (Km25, Sr75, Jm, U6, G8, and Km13). Growth curve, protein level, and protein maximum activity occurred on day-3. The largest diameter of clear zone of six isolates was Km25, Sr75, Jm, U6, G8, and Km13 (3.32, 3.31, 2.41, 2.36, 2.19, and 2.04 mm, respectively). Endoglucanase and exoglucanase maximum activity were 0.011-0.402 IU/mL and 0.0028-0.155 IU/mL, respectively. Conclusion: Six isolates showed high activities of cellulase with diameter of clear zone ≥ 2 cm (Km25, Sr75, Jm, U6, G8, and Km13). Growth maximum curve was on day-3. Highest endo- and exoglucanase activities were on day-3 (0.402 IU/mL and 0.155 IU/mL, respectively) in Jm isolate.

Keywords: Identification, degradation, clear zones, cellulase.
PENGARUH SOLVABILITAS, PROFITABILITAS DAN UKURAN PERUSAHAAN TERHADAP PERATAAN LABA
Authors: Fitri Nur , Sasmita Eyo Asro , Hamzah Amir
Published: March 2019

This study aimed to know the influence of slovency, probability and size company of income smoothing in the sector industrial goods comsumption listed on the indonesian stock exchange. This research is based on theories such as Agency Theory which explains that the practice of income smoothing is influenced by the conflict of interest between the management (agent) and the owner (principal) that arises when each party seeks to achieve or maintain the desired level of prosperity. The sample in this study is determined by Purposive Sampling method based on the criteria of the consumer goods sector companies listed on the stock exchange indonesian and never delisted during the period 2014-2017, to obtained a sample of 26 company. This research used regression model of panel data. The result of this research concludes the result of f test jointly Solvabilitas, Profitability and Size have significant influence to Profit Income. And t test result (partial) Partially variable Solvability and Size Company have positive and significant effect to income smoothing. While Profitability variable has a negative and significant effect to income smoothing. The value of determination coefficient is 91,14% and it can be concluded that Debt to Equity Ratio, Profitability, and Size able to explain variable of Benefit of Earnings.Keywords: Income Smoothing, Solvency, Profitability and Company Size.
AUDIT INTERNAL LEMBAGA KEUANGAN SYARIAH DALAM PERPEKTIF AL-HISBAH
Authors: Baehaqi Ahmad , Suyanto Suyanto
Published: March 2019

Audit Internal Lembaga Keuangan Syariah (LKS) harus memiliki cakupan lebih luas dibandingkan audit konvensional, mengingat LKS memiliki keharusan untuk mematuhi prinsip syariah (sharia compliance). Dalam Islam, institusi al-Hisbah dan muhtasib telah berperan untuk menjaga kegiatan ekonomi masyarakat agar berjalan sesuai dengan tuntunan syariah. Penelitian ini bertujuan untuk mengeksplorasi peranan audit internal LKS dalam perspektif al-Hisbah, untuk menjaga kesesuaian operasional LKS tergadap prinsip syariah. Hasil penelitian menunjukkan bahwa audit internal LKS belum didukung oleh kompetensi syariah yang memadai dan panduan pemeriksaan berkaitan dengan aspek syariah. Audit internal harus berperan membantu Dewan Pengawas Syariah (DPS) dalam melakukan proses pemeriksaan aspek pemenuhan syariah.Kata Kunci: Audit Internal, Sharia Compliance, LKS, al-Hisbah
KESIAPAN KERJA MAHASISWA PROGRAM STUDI AKUNTANSI DALAM MENGHADAPI MASYARAKAT EKONOMI ASEAN (MEA)
Authors: Nurhayati Enung , Martika Lia Dwi
Published: March 2019

Penelitian ini bertujuan untuk menguji pengaruh kompetensi etika, kompetensi pengetahuan, kompetensi kemampuan, kompetensi hubungan dan kompetensi analisis terhadap kesiapan kerja mahasiswa akuntansi baik secara simultan maupun secara parsial.� Populasi dalam penelitian ini adalah mahasiswa aktif program studi akuntansi Fakultas Ekonomi Universitas Kuningan pada tahun 2017. Teknik pengambilan sampel dengan teknik purposive, yaitu mahasiswa aktif program studi akuntansi Fakultas Ekonomi tingkat 3 dan 4. Analisis data menggunakan analisis regresi dilakukan dengan metode analisis regresi berganda. �Hasil penelitian ini menunjukkan bahwa kompetensi etika, kompetensi pengetahuan, kompetensi kemampuan, kompetensi hubungan, dan kompetensi analisis berpengaruh baik secara simultan maupun parsial terhadap kesiapan kerja mahasiswa dalam menghadapi masyarakat ekonomi ASEAN.�Kata kunci: Kompetensi etika, kompetensi pengetahuan, kompetensi kemampuan, kompetensi hubungan, kompetensi analisis, dan kesiapan kerja mahasiswa akuntansi
PENGARUH PERTUMBUHAN PERUSAHAAN, AUDIT TENURE DAN OPINI AUDIT TAHUN SEBELUMNYA TERHADAP OPINI AUDIT GOING CONCERN
Authors: Pratiwi Laras , Lim Tri Hadrianto
Published: March 2019

The going concern audit opinion can used by stakeholders to predict the bankruptcy of a company, therefore the auditor should be responsible of his opinion. This study aims to obtain empirical evidence of the influence company growth, audit tenure and audit opinion of the previous year to going concern audit opinion. Population in this research using data manufacturing companies wich listed on the Indonesia Stock Exchange period 2013-2017. Method of Sampling is purposive sampling. Total sample are 22 companies. Research method using logistic regression analysis model. The results show that company's growth and the previous year's audit opinion affect to going concern audit opinion, while audit tenure doesn't affect to going concern audit opinion.Keywords : Growth, Audit tenure, Going Concern Opinion
Flexibilidade e o alongamento passivo: Comparação entre protocolos com e sem intervalo entre as repetições
Authors: Ribeiro Mara Claudia , Pereira Rafael Santiago , Menezes Thaina Rodrigues de , Franz Pedro Bainy
Published: March 2019

Introdução: Um recurso utilizado por fisioterapeutas para ganho de flexibilidade é o alongamento, sendo realizado de diversas formas. Objetivo: Avaliar e comparar os efeitos de protocolos de alongamento passivo com intervalo entre repetições e sem intervalo entre repetições, no ganho de amplitude de movimento de forma aguda e crônica. Metodologia: Participaram 10 estudantes do gênero feminino, aleatoriamente divididas em dois grupos: G1 (Grupo sem intervalo entre as repetições de alongamento passivo dos músculos isquiotibiais); G2 (Grupo com intervalo entre as repetições de alongamento passivo dos músculos isquiotibiais). O protocolo consistiu na avaliação do ângulo poplíteo após aquecimento. Cada medida foi repetida por três vezes consecutivas, sendo uma mensuração pré-intervenção seguida de uma nova logo após o protocolo de alongamento, repetiu-se a avaliação depois da intervenção e outra, como follow-up, após duas semanas. Resultados: Foi possível constatar que ambos os grupos obtiveram ganho agudo e crônico de flexibilidade. O grupo G1 apresentou tendência ao ganho imediato de flexibilidade maior que o grupo G2. Na avaliação do ganho de flexibilidade crônico, a mesma característica foi observada, uma vez que as voluntárias de ambos os protocolos apresentaram melhora intra grupo, porém não houve diferença significativa quando avaliado qual grupo obteve melhor desempenho. Conclusão: Os protocolos de alongamento muscular utilizados podem influenciar no ganho de flexibilidade que, apesar de ter sido significativo com relação a diferença aguda e crônica intra grupo, o mesmo não ocorreu quando comparados entre grupos.
Infecções relacionadas à assistência à saúde em recém-nascidos de alto risco: perfil de resistência dos bacilos Gram negativos
Authors: Modesto Esther Nicoli , Brito Denise Von Dolinger de
Published: March 2019

Introdução: Infecções Relacionadas à Assistência à Saúde (IRAS) são problemas importantes dentro de uma Unidade de Terapia Intensiva Neonatal (UTIN), onde tanto fatores ambientais quanto intrínsecos do Recém-Nascido (RN) contribuem para a incidência das infecções. IRAS provocadas por bacilos Gram negativos apresentam relevância clínica devido à maior gravidade dos casos e à maior resistência destes patógenos aos antimicrobianos. Objetivo: Objetivou-se verificar a incidência de IRAS por bacilos Gram negativos multirresistentes, descrever os microrganismos identificados nas culturas laboratoriais e avaliar o perfil de resistência aos antimicrobianos.  Metodologia: Foi realizado um estudo retrospectivo, do tipo caso-controle a partir da coleta de dados dos prontuários de 804 RN que estiveram internados na UTIN de um hospital terciário entre janeiro de 2010 e dezembro de 2012. Resultados: Os principais fatores de risco para IRAS: peso de nascimento entre 750g e 1500g e maior que 2500g, idade gestacional entre 26 e 30 semanas, tempo de internação maior que 8 dias, uso de cateter venoso central, uso de ventilação mecânica e nutrição parenteral. A IRAS mais frequente foi a Infecção da Corrente Sanguínea com Confirmação Laboratorial, e dentre os bacilos Gram negativos, a Klebsiella pneumoniae foi a mais frequente. Conclusão: O estudo atendeu aos objetivos propostos e mostrou a importância das ações de vigilância, prevenção e controle das IRAS nas unidades neonatais, reduzindo a ocorrência de agravos à saúde do RN de alto risco, contribuindo para a diminuição dos índices de morbi-mortalidade e promovendo a melhoria da qualidade da assistência no período neonatal.
Capoeira: ferramenta de inclusão nas aulas de educação física para alunos com necessidades educacionais especiais
Authors: Faria Christine Avelar Borges , Pinto Fabrício Aigner , Abreu José Roberto Gonçalves de
Published: March 2019

Objetivo: O objetivo da pesquisa é abranger a capoeira como ferramenta de inclusão nas aulas de educação física para alunos com necessidades educativas especiais, compreendendo os fatores que podem viabilizar este processo. Metodologia: Trata-se de uma pesquisa bibliográfica, pois se baseará, principalmente, de produções técnicas e literárias, artigos, monografias entre outras publicações acerca da temática capoeira, educação física e inclusão. Resultados: Diante do que foi construído, e partindo das limitações encontradas pela falta de produção associada ao tema, pôde-se verificar que a capoeira é uma possibilidade de muitas influências para a pessoa com deficiência. Considerações finais: Concluiu-se que a capoeira pode ser uma ferramenta de inclusão, significativamente possível de ser trabalhada na escola e nas aulas de educação física, pois nela se abrange além da cultura corporal do movimento outros aspectos artísticos, culturais e esportivos que contribuem para esse fim.
Transporte do paciente crítico no ambiente intra hospitalar: uma revisão de literatura
Authors: Martins Tays da Silva , Pádua Vanízia
Published: March 2019

Objetivo: Revisar na literatura científica as formas corretas de transporte do paciente crítico no ambiente intra hospitalar, investigando os fatores que interferem nesse processo. Método: Trata-se de uma revisão de literatura, de caráter descritiva, com abordagem qualitativa. Resultado: Utilizou-se 17 artigos selecionados das bases de dados SciELO, LILACS, BDENF e EBSCO nos anos de 2012 a 2017, além de órgãos competentes sobre o assunto, como Ministério da Saúde e da Educação (EBSERH). Considerações finais: Os fatores que interferem no transporte intra hospitalar do paciente crítico estão relacionados a participação incompleta da equipe multiprofissional, a falha de equipamentos, dificuldade na comunicação entre as equipes de origem e destino e problemas relacionados a infraestrutura.
Análise da qualidade das prescrições médicas em Montes Claros - Minas Gerais
Authors: Murta Inah Araújo de Almeida , Bastos Camila Bacelar , Lacerda Leidiane Vilasboas , Rocha Emanuelly Durães , Gomes Iara Lafetá , França Dorothéa Schmidt
Published: March 2019

Introdução: A prescrição médica é a forma de informação e orientação e a falha nesta pode gerar dúvidas e prejudicar a saúde do paciente. Metodologia: O presente estudo avaliou o perfil de 589 receituários médicos, durante um período de 06 meses, em duas drogarias em Montes Claros - MG, observando principalmente a legalidade dos mesmos. Foram avaliadas onze variáveis foram: identificação do prescritor, identificação do paciente, posologia, tipo de receituário, quantidade de medicamentos por receita, intervalo das doses, orientações, assinatura e carimbo médicos.  A coleta foi realizada pelo sistema de amostragem aleatória simples, as mesmas foram submetidas a análise e comparadas com a literatura que versa sobre o tema. Resultados: Nas 510 receitas consideradas legais, 504 (98,8%) continham assinatura do prescritor, 496 (97,2%), número de inscrição no CRM e 399 (78,2%) o endereço. Em relação aos dados do paciente, 509 (99,8%) apresentaram o nome e apenas 09 (1,76%) o endereço. Conclusão: É relevante que sejam estabelecidas estratégias que visem à oferta de orientações considerando o nível de entendimento dos usuários individualmente, o que pode ser atingido com a criação do Serviço de Atenção Farmacêutica e educação continuada de médicos.
Efficacy and Safety of Apremilast in Patients With Moderate to Severe Plaque Psoriasis of the Scalp: Results of a Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study
Authors: Van Voorhees Abby , Stein Gold Linda , Lebwohl Mark , Al. Et
Published: March 2019

Abstract not available. Disclosures: Study sponsored by Celgene.
Secukinumab Is Associated With Improvements in Real-World Effectiveness Outcomes Through 12 Months of Follow-Up in Patients With Plaque Psoriasis: Analysis of US Dermatology Electronic Medical Records
Authors: Yamauchi Paul , Chen Chi-Chang , Ding Yao , Al. Et
Published: March 2019

Abstract not available. Disclosures: Study sponsored by Novartis.
SkinSpecs: A solution that addresses an unmet need for tracking chronic skin diseases in the office and at home
Authors: Afanasiev Olga
Published: March 2019

Not available.
Pharmacokinetics of Minocycline Foam FMX103 in Subjects With Moderate-to-Severe Facial Papulopustular Rosacea Under Maximum-Use Conditions: Results of a Phase 1 Study
Authors: Jones Terry , Stuart Iain
Published: March 2019

Abstract not available. Disclosures: Study sponsored by Foamix Pharmaceuticals.
Effect of Suture Spacing on Wound Cosmesis
Authors: Eshagh Karin
Published: March 2019

Not available.
Development and validation of the tape-to-trace method: An objective outcome measure for linear postoperative scars
Authors: Feldstein Stephanie
Published: March 2019

Not available.
Cell Cycle Activators and Tumor Suppressors that Correlate with Melanoma Progression
Authors: Min Michelle
Published: March 2019

Not available.
Tackling lower extremity surgical site infection in dermatologic surgery
Authors: Nathan Neera
Published: March 2019

Not available.
Understanding of abbreviations in dermatology: A survey of primary care providers.Understanding of abbreviations in dermatology: A survey of primary care providers
Authors: Rohr Bethany
Published: March 2019

Not available.
Meeting the Challenges of the Dermatomyositis Workup: A Management Paradigm
Authors: Alkeswani Amena , Graham Lauren V
Published: March 2019

Dermatomyositis (DM) is a rare inflammatory myopathy with characteristic skin manifestations. This multisystem disorder is characterized by an increased frequency of pulmonary disease and malignancy. It has a female to male predominance of 2:1, with an average age at diagnosis of 40 years [1]. Diagnosing DM can be challenging due to the heterogeneity of presentations and clinical features that may overlap with other disorders. Although DM has had an established diagnostic criteria by Bohan and Peter since 1975, groups have re-examined the criteria to highlight the importance of skin findings [2-4]. This article will discuss the process of working-up dermatomyositis in an adult from a dermatologist’s point of view.
Caffeine in the Treatment of Atopic Dermatitis and Psoriasis: A Review
Authors: Alashqar Mais Bassam
Published: March 2019

Atopic dermatitis (AD) and psoriasis are inflammatory skin diseases. AD is characterized by immune dysregulation and barrier impairment, while psoriasis is by immune dysfunction and resultant keratinocyte hyper-proliferation.    Caffeine has shown effective in ameliorating the symptoms of both diseases, but it is not conclusive through which pathways. The aim of this study was to provide a detailed discussion of available work on this topic, as well as known modes of action of caffeine that are relevant to these two conditions.    After an extensive review of the literature, we found that both diseases have decreased intracellular cyclic adenosine monophosphate (cAMP) levels in cutaneous leukocytes, so it is very likely that being a methylxanthine, and hence a phosphodiesterase (PDE) inhibitor, caffeine raises intracellular cAMP levels, which suppresses inflammatory pathways and potentiates anti-inflammatory ones. Moreover, caffeine is known to be an ATR (ataxia-telangiectasia mutated) kinase and an ATM (ATM- and Rad3-Related) kinase inhibitor, which promotes prompt apoptosis of damaged cells. It was also found to have anti-necrotic effects in reactive oxygen species (ROS)-damaged cells. These pro-apoptotic and anti-necrotic properties may also be reducing the inflammation. Finally, caffeine's metabolites have shown antioxidising effects against ROS, which certainly would reduce inflammation caused by lipid peroxidation, DNA damage and organelle destruction.    We find that caffeine acts in a number of ways to improve symptoms of inflammation and that it is an effective adjunct to therapy in AD and psoriasis.
Review of suicide and depression in psoriasis and management of suicide warnings in patients treated with psoriasis drugs
Authors: Lebowitz Emily , Lebwohl Mark
Published: March 2019

Patients with psoriasis are thought to be at increased risk of depression, anxiety and suicidality predominantly as a result of the psychosocial impact of this disease. Studies have shown that the pro-inflammatory cytokines that are elevated in psoriasis and targeted by biologics have also been identified in patients with depression. It is therefore thought that anti-cytokine therapies may improve patients’ quality of life not only by reducing their disease burden but also by modulating the inflammatory pathways implicated in depression. While depression is mentioned in the package inserts of brodalumab and apremilast, only brodalumab has a black box warning requiring discussion of suicidality prior to prescribing the drug. In clinical trials, the majority of patients receiving brodalumab experience a reduction in symptoms of depression and anxiety. The package insert for brodalumab points out that no causal association has been established between brodalumab and suicide, and the FDA-mandated Risk Evaluation and Mitigation Strategies (REMS) program for brodalumab takes only minutes to complete. Brodalumab and apremilast may therefore be considered for patients in whom depression is caused by psoriasis, provided that patients and their providers have a mutual understanding of the risks and benefits of these therapies and the REMS program is followed.
Nobel Niels
Authors: Benavidez Jacob E
Published: March 2019

Not available.
Assessing Patient Satisfaction With Hydrogen Peroxide Topical Solution, 40% (w/w) Treatment of Seborrheic Keratoses on the Face, Neck, and Décolletage: Objectives and Design of the Phase 4, Open-Label SK-FAN Study
Authors: Dubois Janet , Grande Kimberly , Schnyder Judith , Al. Et
Published: March 2019

Abstract not available. Disclosures: Study sponsored by Aclaris.