bluuebunny/crossref_metadata_2025 huggingface dataset:
COVID-19 and global supply chain risks mitigation: systematic review using a scientometric technique
Authors: Fernando Yudi , Al-Madani Mohammed Hammam Mohammed , Shaharudin Muhammad Shabir
Published: July 2023

Purpose

This paper aims to investigate how manufacturing firms behave to mitigate business risk during and post-COVID-19 coronavirus disease (COVID-19) on the global supply chain.

Design/methodology/approach

A systematic literature review for data mining was used to address the research objective. Multiple scientometric techniques (e.g. bibliometric, machine learning and social network analysis) were used to analyse the Lens.org, Web of Science and Scopus databases’ global supply chain risk mitigation data.

Findings

The findings show that the firms’ manufacturing supply chains used digitalisation technologies such as Blockchain, artificial intelligence (AI), 3D printing and machine learning to mitigate COVID-19. On the other hand, food security, government incentives and policies, health-care systems, energy and the circular economy require more research in the global supply chain.

Practical implications

Global supply chain managers were advised to use digitalisation technology to mitigate current and upcoming disruptions. The manufacturing supply chain has high uncertainty and unpredictable global pandemics. Manufacturing firms should consider adopting Blockchain technology, AI and machine learning to mitigate the epidemic risk and disruption.

Originality/value

This study found the publication trend of how manufacturing firms behave to mitigate the global supply chain disruptions during the global pandemic and business uncertainty. The findings have contributed to the supply chain risk mitigation literature and the solution framework.
Social enterprise housing supply chains for resource-constrained communities: a complexity lens approach
Authors: Boehme Tillmann , Fan Joshua , Birtchnell Thomas , Aitken James , Turner Neil , Deakins Eric
Published: July 2023

Purpose

Delivering housing to resource-constrained communities (RCCs) is a complex process beset with difficulties. The purpose of this study is to use a complexity lens to examine the approach taken by a social enterprise (SE) in Australia to develop and manage a housebuilding supply chain for RCCs.

Design/methodology/approach

The research team used a longitudinal case study approach from 2017 to 2022, which used mixed methods to understand the phenomenon and gain an in-depth understanding of the complex issues and problem-solving undertaken by an SE start-up.

Findings

Balancing mission logic with commercial viability is challenging for an SE. The supply chain solution that evolved accommodated the particulars of geography and the needs of many stakeholders, including the end-user community and government sponsors. Extensive and time-consuming socialisation and customisation led to a successful technical design and sustainable supply chain operation.

Practical implications

Analysing supply chain intricacies via a complexity framework is valuable for scholars and practitioners, assisting in designing and developing supply chain configurations and understanding their dynamics. Meeting the housing construction needs of RCCs requires the SE to place societal focus at the centre of the supply chain rather than merely being a system output. The developed business model complements the engineering solution to empower a community-led housing construction supply chain.

Originality/value

This longitudinal case study contributes to knowledge by providing rich insights into the roles of SEs and how they develop and operate supply chains to fit with the needs of RCCs. Adding a contextual response dimension to an established complexity framework helped to explain how hybrid organisations balance commercial viability demands with social mission logic by amending traditional supply chain and governance practices. The case provides insights into supply chain configuration, needed changes and potential impacts when an SE as a focal actor inserts into a traditional for-profit construction supply chain.
Concomitant gallstone disease was not associated with long‐term outcomes in ursodeoxycholic acid‐treated patients with primary biliary cholangitis
Authors: Chen Sha , Li Meng Qi , Li Bu Er , Lv Ting Ting , Li Shu Xiang , Shan Shan , Li Min , Kong Yuan Yuan , Zhang Dong , Ma Hong , Ou Xiao Juan , You Hong , Duan Wei Jia , Jia Ji Dong
Published: July 2023

Objectives

Primary biliary cholangitis (PBC) is a rare disease characterized by intrahepatic cholestasis, whereas gallstone disease (GD) is common. In this study, we aimed to investigate the prevalence and impact of GD on the prognosis of PBC in China.

Methods

Medical records of the PBC patients were retrospectively reviewed and their follow‐up data were obtained via regular structured, standardized telephone interviews. GD was defined as gallstones on ultrasonography or a history of cholecystectomy for gallstones. Propensity score matching (PSM) and Cox regression analysis were performed. The primary end‐point was liver‐related death and/or liver transplantation.

Results

A total of 985 ursodeoxycholic acid (UDCA)‐treated PBC patients were enrolled with a median follow‐up duration of 5.3 years (range 1.0–20.9 years). Among them, 258 (26.2%) had GD, including 157 (22.9%) of non‐cirrhotic and 101 (33.8%) of cirrhotic patients. Compared with PBC without GD, those with GD were older, more often had type 2 diabetes mellitus, and had a more severe liver disease at baseline. After PSM (1:2), 229 PBC patients with GD were matched with 458 PBC patients without GD based on age, sex, cirrhosis, and total bilirubin level. The transplant‐free survival and incidence of hepatic events were similar between the two groups. Furthermore, multivariate Cox regression analysis showed that concomitant GD was not independently associated with a worse prognosis for PBC patients.

Conclusion

Concomitant GD was common but was not associated with long‐term outcomes in patients with UDCA‐treated PBC.
Organic Matter Accumulation in the Upper Permian Dalong Formation from the Lower Yangtze Region, South China
Authors: FANG Chaogang , ZHANG Chengcheng , MENG Guixi , XU Jinlong , XU Naicen , LI Hualing , LIU Mu , LIU Bo
Published: July 2023

The Late Permian was marked by a series of important geological events and widespread organic‐rich black shale depositions, acting as important unconventional hydrocarbon source rocks. However, the mechanism of organic matter (OM) enrichment throughout this period is still controversial. Based on geochemical data, the marine redox conditions, paleogeographic and hydrographic environment, primary productivity, volcanism, and terrigenous input during the Late Permian in the Lower Yangtze region have been studied from the Putaoling section, Chaohu, to provide new insights into OM accumulation. Five Phases are distinguished based on the TOC and environmental variations. In Phase I, anoxic conditions driven by water restriction enhanced OM preservation. In Phase II, euxinic and cycling hydrological environments were the two most substantial controlling factors for the massive OM deposition. During Phase III, intensified terrestrial input potentially diluted the OM in sediment and the presence of oxygen in bottom water weakened the preservation condition. Phase IV was characterized by a relatively higher abundance of mercury (Hg) and TOC (peak at 16.98 wt%), indicating that enhanced volcanism potentially stimulated higher productivity and a euxinic environment. In Phase V, extremely lean OM was preserved as a result of terrestrial dilutions and decreasing primary productivity. Phases I, II and IV are characterized as the most prominent OM‐rich zones due to the effective interactions of the controlling factors, namely paleogeographic, hydrographic environment, volcanism, and redox conditions.
Farm‐level responses to weather trends: A structural model
Authors: Wimmer Stefan , Stetter Christian , Schmitt Jonas , Finger Robert
Published: July 2023

Assessing the effects of weather and climate on agricultural production is crucial for designing policies related to climate change adaptation and mitigation. A large body of literature has identified the detrimental effects of climate change on crop yields worldwide, and farm‐level adaptation has been shown to mitigate the adverse effects on agricultural production. In this study, we employ a structural model to examine farm production responses to ongoing weather trends. We investigate how farmers adjust output and input decisions by estimating a system of output supply and input demand functions, controlling for nonrandom crop selection. Using panel data with 14,796 observations reflecting 1638 German crop farms (1996–2019), we find that both the expected and realized weather determine farmers' production decisions. In the event of a drought, the supply of most considered crops and the demand for fertilizer decrease. The drought shock has also lasting effects on farmers' production decisions, with a reduced supply of protein crops and an increased level of root crops production in subsequent years. These findings highlight the need to account for farm‐level production responses when assessing weather and climate impacts.
Gamified monetary reward designs: Offering certain versus chance‐based rewards
Authors: Adam Martin , Reinelt Annika , Roethke Konstantin
Published: July 2023

To motivate visitors to engage with websites, e‐tailers widely employ monetary rewards (e.g., vouchers, discounts) in their website designs. With advances in user interface technologies, many e‐tailers have started to offer gamified monetary reward designs (MRDs), which require visitors to earn the monetary reward by playing a game, rather than simply claiming the reward. However, little is known about whether and why gamified MRDs engage visitors compared to their non‐gamified counterpart. Even less is known about the effectiveness of gamified MRDs when providing certain or chance‐based rewards, in that visitors do or do not know what reward they will gain for successfully performing in the game. Drawing on cognitive evaluation theory, we investigate gamified MRDs with certain or chance‐based rewards and contrast them to non‐gamified MRDs with certain rewards in user registration systems. Our results from a multi‐method approach encompassing the complementary features of a randomised field experiment (N = 651) and a randomised online experiment (N = 330) demonstrate differential effects of the three investigated MRDs on user registration. Visitors encountering either type of gamified MRD are more likely to register than those encountering a non‐gamified MRD. Moreover, gamified MRDs with chance‐based rewards have the highest likelihood of user registrations. We also show that MRDs have distinct indirect effects on user registration via anticipated experiences of competence and sensation. Overall, the paper offers theoretical insights and practical guidance on how and why gamified MRDs are effective for e‐tailers.
Clinical characteristics and survival analysis of cutaneous metastases in a single tertiary centre in Korea
Authors: Shin Dong Min , Jung Yeon Joo , Kim Heeyeon , Oh Se Jin , Shim Joonho , Lee Jong Hee , Lee Dong‐Youn , Park Jihye
Published: July 2023

Background

Cutaneous metastasis (CM) refers to the spread of malignancy to the skin. CM is perceived as an advanced stage. It might be the first sign of a primary cancer or an indicator of recurrence.

Objectives

To identify primary cancers associated with CMs and perform a survival analysis according to advanced stage of cutaneous metastasis at a single tertiary centre in Korea.

Methods

A total of 219 patients from Samsung Medical Center from January 2009 to April 2020 were retrospectively analysed to identify cases with biopsy‐proven CMs. According to advanced stage of metastasis, patients were divided into three stages, CM only (CMO), CM with lymph node metastasis (CM/LM) and CM with distant metastasis (CM/DM), to analyse clinical characteristics and survival rate.

Results

The most common CM from primary cancer was breast cancer, followed by lung cancer, stomach cancer, colorectal cancer and others. When all primary cancers were included, the median survival period was 4.82 years for the CMO stage, 2.15 years for the CM/LM stage and 0.80 years for the CM/DM stage, with a tendency to deteriorate with advancing stage. At 1‐ and 3‐year after occurrence of CM, the CM/DM stage showed a significantly poorer survival rate than the other two stages.

Conclusions

This study showed a median survival period of 22 months for CM patients overall. Breast cancer has greater accessibility to the skin than other cancers. Therefore, breast cancer can metastasize to the skin without involving lymph nodes or other sites.
Risk of variant Creutzfeldt–Jakob disease in a simulated cohort of Canadian blood donors
Authors: Pozzo di Borgo Alexis , Germain Marc , O'Brien Sheila F. , Delage Gilles , Renaud Christian , Lewin Antoine
Published: July 2023

Background and Objectives

No transfusion‐associated cases of variant Creutzfeldt–Jakob disease (vCJD) have occurred in more than 20 years. Yet, many countries have maintained blood donor deferral criteria for vCJD. We developed a risk simulation model to reassess the need for vCJD‐related deferral criteria in Canada.

Materials and Methods

The model provides results separately for Héma‐Québec (HQ) and Canadian Blood Services (CBS). The model used a Monte Carlo simulation approach to estimate the risk of having a vCJD‐contaminated blood donation (‘risk of vCJD’) in a simulated cohort of 10 million donors followed for up to 85 years. The model assumed current deferral criteria for vCJD were lifted, which would allow new ‘at‐risk’ donors to give blood. The model accounted for disease prevalence, donors' travel/immigration history, PRNP genotype at codon 129, demographics and the type of labile blood product.

Results

In the base case, the risk of vCJD was estimated at zero at both blood services. In the most pessimistic scenario, the risk of vCJD was 6.4 × 10−9 (i.e., 1 in 157 million donations) at HQ, or ≤1 in 77 million based on the upper bound of the 95% confidence interval (CI). At CBS, this risk was 4.8 × 10−8 (i.e., 1 in 21 million donations), or ≤1 in 16 million based on the upper bound of the 95% CI.

Conclusion

vCJD poses minimal risks to the Canadian blood supply. Current vCJD deferral criteria may, therefore, be lifted with virtually no impact on safety, while significantly expanding the donor base.
Age and Isotope-Geochemical Characteristics of Ta, Nb, W, Sn Mineralization Associated with Rare-Metal Granites (Khangilay Ore District, Eastern Transbaikalia)
Authors: Badanina E. V. , Syritso L. F. , Ivanova A. A. , Rizvanova N. G.
Published: July 2023

The age relations between the formation of the parent massif and the crystallization time of the associated ore mineralization were established based on isotope-geochronological study of the massif-deposits of the Khangilay ore cluster with various metallogenic specialization in Eastern Transbaikalia. In the Orlovka Li–F granite massif, the crystallization time of columbite–tantalite (145 ± 1 Ma) and cassiterite (144.2 ± 0.3 Ma) (U-Pb, ID-TIMS) is almost identical to the crystallization time of zircon (140.6 ± 2.9 Ма (U-Pb, SHRIMP) and 145 ± 1 Ma (U-Pb, CA-ID-TIMS)), which is an age marker of the formation of massifs. This fact testifies to the magmatogenic nature of rare-metal mineralization. In the Spokojnoye massif – the “standard type” of rare-metal peraluminous granites—a 0.6–3.8 Ma time gap was revealed between the time of massif formation (141.3 ± 1.8 Ма, U-Pb, SHRIMP, 146.9 ± 0.7 Ма, Rb-Sr isotopic system) and crystallization of wolframite (141.8 ± 0.6, Rb-Sr isotopic system and 140.1 ± 1.4 Ма, Sm-Nd isotopic system). This interval likely corresponds to the life time of the hydrothermal system, which produced tungsten mineralization.
Neurocysticercosis: diagnosis via metagenomic next-generation sequencing
Authors: Pedrosa Denison Alves , Bruniera Peres Fernandes Gustavo , Filipe de Souza Godoy Luís , C Felício André , Pinho João Rebello , Mário Doi André , de Araújo Gleizer René
Published: July 2023

A 68-year-old Brazilian woman had 3 months of progressive fatigue, difficulty walking and 18 kg weight loss. On examination, there was gait apraxia and executive dysfunction. MR scan of brain showed communicating hydrocephalus and a cerebrospinal fluid showed 105 white cells/µL (≤5), predominantly lymphocytes, protein of 1.35 g/L (0.15–0.45) and the glucose content of 0.06 mmol/L (3.3–4.4). We suspected an infective cause and used of metagenomic next-generation sequencing to diagnose neurocysticercosis. This case highlights the challenge of diagnosing chronic meningitis and the relevance of genetic approaches in diagnosing neurological infections.
4-Total domination game critical graphs
Authors: Worawannotai Chalermpong , Charoensitthichai Karnchana
Published: July 2023

The total domination game is played on a simple graph [Formula: see text] with no isolated vertices by two players, Dominator and Staller, who alternate choosing a vertex in [Formula: see text]. Each chosen vertex totally dominates its neighbors. In this game, each chosen vertex must totally dominates at least one new vertex not totally dominated before. The game ends when all vertices in [Formula: see text] are totally dominated. Dominator’s goal is to finish the game as soon as possible, and Staller’s goal is to prolong it as much as possible. The game total domination number is the number of chosen vertices when both players play optimally, denoted by [Formula: see text] when Dominator starts the game and denoted by [Formula: see text] when Staller starts the game. If a vertex [Formula: see text] in [Formula: see text] is declared to be already totally dominated, then we denote this graph by [Formula: see text]. A total domination game critical graph is a graph [Formula: see text] for which [Formula: see text] holds for every vertex [Formula: see text] in [Formula: see text]. If [Formula: see text], then [Formula: see text] is called [Formula: see text]-[Formula: see text]-critical. In this work, we characterize some 4-[Formula: see text]-critical graphs.
Data from Genomic profiling of metastatic castration-resistant prostate cancer samples resistant to androgen-receptor pathway inhibitors
Authors: Menssouri Naoual , Poiraudeau Loic , Helissey Carole , Bigot Ludovic , Sabio Jonathan , Ibrahim Tony , Pobel Cedric , Nicotra Claudio , Ngo-Camus Maud , Lacroix Ludovic , Rouleau Etienne , Tselikas Lambros , CHAUCHEREAU Anne , Blanc-Durand Félix , Bernard-Tessier Alice , Patrikidou Anna , Naoun Natacha , Flippot Ronan , Colomba Emeline , Fuerea Alina , Albiges Laurence , Lavaud Pernelle , van de Wiel Paul , den Biezen-Timmermans Eveline , Wesseling-Rozendaal Yvonne , Ponce-Aix Santiago , Michiels Stefan , Massard Christophe , Gautheret Daniel , Barlesi Fabrice , Andre Fabrice , Besse Benjamin , Scoazec Jean-Yves , Friboulet Luc , Fizazi Karim , Loriot Yohann
Published: July 2023

Abstract
Purpose: The androgen receptor axis inhibitors (ARPI) (e.g, enzalutamide, abiraterone acetate) are administered in daily practice for men with metastatic castration-resistant prostate cancer (mCRPC). However, not all patients respond, and mechanisms of both primary and acquired resistance remain largely unknown Experimental Design: In a prospective trial MATCH-R (NCT02517892), 59 mCRPC patients underwent whole exome sequencing (WES) and/or RNA-sequencing (RNA-seq) of samples collected before starting ARPI. Also, 18 mCRPC patients underwent biopsy at time of resistance. The objectives were to identify genomic alterations associated with resistance to ARPIs as well as to describe clonal evolution. Associations of genomic and transcriptomic alterations with primary resistance were determined using Wilcoxon and Fisher's exact tests. Results: WES analysis indicated that no single-gene genomic alterations was strongly associated with primary resistance. RNA-seq analysis showed that AR gene alterations and expression levels were similar between responders and non-responders. RNA-based pathway analysis found that patients with primary resistance had a higher Hedgehog pathway score, a lower AR pathway score and a lower NOTCH pathway score than patients with a response. Subclonal evolution and acquisition of new alterations in AR-related genes or neuroendocrine differentiation are associated with acquired resistance. ARPIs do not induce significant changes in the tumor transcriptome of most patients; however, programs associated with cell proliferation are enriched in resistant samples. Conclusions:Low AR activity, activation of stemness programs, and Hedgehog pathway were associated with primary ARPIs’ resistance, whereas most acquired resistance was associated with subclonal evolution, AR-related events, and neuroendocrine differentiation
Leveraging pre-trained language models for mining microbiome-disease relationships
Authors: Karkera Nikitha , Acharya Sathwik , Palaniappan Sucheendra K.
Published: July 2023

Background

The growing recognition of the microbiome’s impact on human health and well-being has prompted extensive research into discovering the links between microbiome dysbiosis and disease (healthy) states. However, this valuable information is scattered in unstructured form within biomedical literature. The structured extraction and qualification of microbe-disease interactions are important. In parallel, recent advancements in deep-learning-based natural language processing algorithms have revolutionized language-related tasks such as ours. This study aims to leverage state-of-the-art deep-learning language models to extract microbe-disease relationships from biomedical literature.

Results

In this study, we first evaluate multiple pre-trained large language models within a zero-shot or few-shot learning context. In this setting, the models performed poorly out of the box, emphasizing the need for domain-specific fine-tuning of these language models. Subsequently, we fine-tune multiple language models (specifically, GPT-3, BioGPT, BioMedLM, BERT, BioMegatron, PubMedBERT, BioClinicalBERT, and BioLinkBERT) using labeled training data and evaluate their performance. Our experimental results demonstrate the state-of-the-art performance of these fine-tuned models ( specifically GPT-3, BioMedLM, and BioLinkBERT), achieving an average F1 score, precision, and recall of over $$>0.8$$

>
0.8

compared to the previous best of  0.74.

Conclusion

Overall, this study establishes that pre-trained language models excel as transfer learners when fine-tuned with domain and problem-specific data, enabling them to achieve state-of-the-art results even with limited training data for extracting microbiome-disease interactions from scientific publications.
Iron accumulation and lipid peroxidation: implication of ferroptosis in diabetic cardiomyopathy
Authors: Yan Xuehua , Xie Yang , Liu Hongbing , Huang Meng , Yang Zhen , An Dongqing , Jiang Guangjian
Published: July 2023

Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure and even death. Currently, the pathogenesis of DC is unclear, and clinical intervention is mainly symptomatic therapy and lacks effective intervention objectives. Iron overdose mediated cell death, also known as ferroptosis, is widely present in the physiological and pathological processes of diabetes and DC. Iron is a key trace element in the human body, regulating the metabolism of glucose and lipids, oxidative stress and inflammation, and other biological processes. Excessive iron accumulation can lead to the imbalance of the antioxidant system in DC and activate and aggravate pathological processes such as excessive autophagy and mitochondrial dysfunction, resulting in a chain reaction and accelerating myocardial and microvascular damage. In-depth understanding of the regulating mechanisms of iron metabolism and ferroptosis in cardiovascular vessels can help improve DC management. Therefore, in this review, we summarize the relationship between ferroptosis and the pathogenesis of DC, as well as potential intervention targets, and discuss and analyze the limitations and future development prospects of these targets.
Causes of depressive disorders and their degree and severity among high school students
Authors: Zając Anna , Dobko Katarzyna , Frącz Gabriela , Glac Agata , Kuliga Klaudia , Musz Kinga , Sejnowska Natalia , Socha Agnieszka , Surowiec Agata , Śnieżek Kinga
Published: July 2023

Introduction: Depressive disorders are common in children and adolescents, but often go undiagnosed. They are associated with serious consequences, as well as with serious impairments both in terms of personal and social life, increasing the risk of suicide and psychoactive substance abuse.

 

Objective: The aim of the study was to analyze the most common factors causing depressive disorders and to assess their frequency and severity among adolescents.

 

Materials and methods:The study was conducted in one of the secondary schools in Krosno. 316 students (245 girls, 71 boys) aged 15 to 19 participated in the study. The results of 27 questions on depressive disorders were obtained using an anonymous online questionnaire.

 

Results: Among 316 students, as many as 40.5% do not know whether they suffer from depressive disorders, while 12% are sure of it, of which 71% have started treatment. However, sadness and depression as well as loss of interest and pleasure from doing favorite activities lasting 2 weeks or more, as well as a sense of worthlessness and lower self-esteem reach over 27% of students. The study shows that 15% of students may be undiagnosed. Suicidal thoughts occur in 44.9% of the respondents. 6.3% of students have attempted suicide and 2.8% want to take their own lives.

 

Conclusions: Depressive disorders are a common problem among hight school studnets. The most common disorders coexisting with depression in the examined adolescents were eating disorders. Increased awareness of depression symptoms among adolescents, parents, school psychologist and family doctor is a key element for diagnosis and therapy.
Soil macrofauna diversity and weed dynamics in response to different methods of weed control in smallholder rubber farming
Authors: CHANIAGO IRAWATI , YULISTRIANI YULISTRIANI , UMAMI IRWIN M. , BUKHARI ZAM Z.
Published: July 2023

Abstract. Chaniago I, Yulistriani, Umami IM, Bukhari ZZ. 2023. Soil macrofauna diversity and weed dynamics in response to different methods of weed control in smallholder rubber farming. Biodiversitas 24: 3106-3113. Weeds interference in rubber farmland may reduce latex yield. Farmers apply herbicides to control weeds. However, the herbicide not only controls weed but also affects the presence of soil macrofauna. A study has been conducted to determine the effect of different method of weed control on soil macrofauna and weeds at smallholder rubber farming at Pulau Punjung, Dharmasraya District, West Sumatra, Indonesia. The experiment was conducted in a completely randomized block design with 6 treatments and 4 pseudo-replications. Treatment was mechanical control, without weed control, and 4 doses of herbicide glyphosate+metsulfuron-methyl (1.5 L ha-1 + 15 g ha-1, 2 L ha-1 + 15 g ha-1, 2.5 L ha-1 + 15 g ha-1, 3 L ha-1 + 15 g ha-1) with 400 L ha-1 of volume. Pitfall traps were used to collect the soil macrofauna. Data were analysis with ANOVA for weed and soil macrofauna in response to different methods of weed control. Results demonstrated that the application of glyphosate+metsulfuron-methyl herbicide significantly suppressed weeds higher than that of other methods of weed control (p<0.05). Para grass (Brachiaria mutica (Forssk.) Stapf) was the most dominant weed but has been affected most by 3 L ha-1 + 15 g ha-1 herbicide mixture. Soil macrofauna of the order Hemiptera was affected most by the application of herbicide with a total reduction of 71.58% of number of individuals at 12 weeks after application of herbicide. In general, different weed control methods resulted in varied numbers of orders and individuals of the soil macrofauna.
The Periodization and Analytical Framework of Economic Long Waves: A New Study from the Perspective of Historical Materialism
Authors: Hu Leming , Liu Gang , Gao Guiai
Published: July 2023

Proceeding from the perspective of historical materialism, this article examines technological revolution and industrial revolution as intermediate-level concepts for analyzing economic long waves, and reconstructs the political economy analysis framework of long-wave theory. Based on this framework, and in order to avoid a “mismatch” between economic long waves and the cycle of technological revolution, this article modifies the traditional method of periodizing economic long waves from trough to trough, instead employing the method of periodizing them from peak to peak as proposed by Perez. In this way, this article alters the periodization of economic long waves from the traditional five “inverted V-shaped” long waves to six “V-shaped” long waves. Within each industrial revolution, the technological revolution and institutional change that occur correspond to two “W-shaped” long-wave trends. Economic long waves are thus shown to be in essence external manifestations of the trend of evolution of the mode of production. In the final analysis, long-wave theory should not only reveal the decisive role of productivity and the mechanism of interaction between technology and the economy, but should also reveal the long-term changes undergone by politics and culture, and the laws that apply to them.
Breaking performance limit for waveguide sensor: a way of both enhancing sensitivity and quality factor
Authors: Jian Aoqun , li min , zhao biao , sang luxiao , ding jinyu , Zhang Xuming , Sang Shengbo
Published: July 2023

In the present study, a dual-dielectric planar waveguides （PWGs） coupling sensor was developed to break the waveguide performance limit. Its designs consisted of a sensor planar waveguide （PWG1） for the realization of multimode sensing and a reference planar waveguide (PWG2) for the realization of Fano and EIT-like resonance. The sensitivity and quality factor （Q） of the device was shown to achieve values of up to 7.8×104 nm/RIU and 4843.75, respectively, allowing its applicability for bulk refractive index （RI） sensing. This yielded an impressive figure of merit （FOM） of 2.2×105 RIU-1, which was the highest reported FOM for an RI sensor. Furthermore, a biosensor designed in this work displayed high-resolution capability and good linearity, along with a limit of detection （LOD） down to 0.14 mg/dL for label-free glucose measurement. This suggests the vast potential for environmental protection, drinking water safety, and biomedical discoveries.
Spatial localization ability of planarians identified through a light maze paradigm
Authors: Qian Renzhi , Yan Yuan , Pei Yu , Zhang Yixuan , Chi Yuanwei , Chen Yuxuan , Hao Kun , Xu Zhen , Yang Guang , Shao Zilun , Wang Yuhao , Li Xinran , Lu Chenxu , Zhang Xuan , Chen Kehan , Zhang Wenqiang , Wang Baoqing , Ying Zhengxin , Huang Kaiyuan
Published: July 2023

Spatial localization ability is crucial for free-living animals to fit the environment. As shown by previous studies, planarians can be conditioned to discriminate directions. However, due to their simplicity and primitiveness, they had never been considered to have true spatial localization ability to retrieve locations of objects and places in the environment. Here, we introduce a light maze training paradigm to demonstrate that a planarian worm can navigate to a former recognized place from the start point, even if the worm is transferred into a newly produced maze. This finding identifies the spatial localization ability of planarians for the first time, which provides clues for the evolution of spatial learning. Since the planarians have a primitive brain with simple structures, this paradigm can also provide a simplified model for a detailed investigation of spatial learning.
Alfabetización Multimodal
Authors: Guzmán Diego
Published: July 2023

En la búsqueda por extender los aprendizajes de la investigación en alfabetización hacia otros campos creativos, el presente artículo estudia la relación recíproca entre la comunicación y la alfabetización desde una perspectiva histórica, subrayando la relación entre las tecnologías mediáticas y los procesos sociales y cognitivos mediante los que percibimos, aprendemos y transformamos el mundo.

A través de diferentes ejemplos, el texto ilustra la continuidad entre diferentes modos de expresión y la versatilidad de las herramientas compositivas para escribir en diversos lenguajes, que a su vez dan cuenta de las competencias necesarias para su lectura. Reflexiono en torno a las propiedades del campo de la comunicación a partir de diferentes modelos gráficos que exploran la forma, estructura y relaciones entre diferentes modos de comunicación.

Finalmente, las conclusiones apuntan hacia el estudio de la comunicación de manera fenomenológica y material, como un campo que da forma y evidencia la cultura, que nos permite ver más allá de las disciplinas y los oficios, para abordarla desde la complejidad, como un fenómeno inteligible y peculiar a través del cual le damos sentido a nuestra realidad.
História Comparada do Ensino Secundário: renovação da historiografia por comparações, transições, massificações e traduções
Authors: Pessanha Eurize Caldas , Silva Fabiany de Cássia Tavares
Published: July 2023

Este dossiê ancora-se em resultados organizados pela pesquisa Ensino Secundário no Brasil em Perspectiva Histórica e Comparada (1942-1961), informados pela focalização nos processos de implantação, expansão e organização, no período de 1931 (Reforma Francisco Campos) a 1971 (Lei 5692 de 1971), do Ensino Secundário em instituições públicas e privadas, distribuídas por estados brasileiros, e; em projeções endereçadas pela pesquisa Por Uma Outra Historiografia do Ensino Secundário (1931 a 1961): estudos comparados como ferramenta de construção, ambas orientadas pela perspectiva de outras escritas acerca das percepções dos deslocamentos, das transformações, das construções de modelos e tipologias, bem como da identificação de continuidades e descontinuidades, semelhanças e diferenças na história dos diferentes ensinos secundários “regionalizados ou estadualizados”.
A História da Educação em movimento: entre arquivos, sujeitos e atores
Authors: Rocha Ana Cristina Santos Matos
Published: July 2023

História da Educação: sujeitos, objetos e práticas, organizado por Mirian Jorge Warde e Fernando Rodrigues de Oliveira, é fruto do trabalho desenvolvido na linha de pesquisa homônima do Programa de Pós-Graduação em Educação da Unifesp – Guarulhos, ao qual os autores estão vinculados. Em formato digital e acesso aberto, o livro apresenta os resultados das pesquisas do grupo, que dialoga com conceitos e debates da história cultural, intelectual e política. Ao reunir autores em diferentes estágios profissionais e de formação em pesquisa, a leitura deste volume nos mostra como é possível revisitar temas já tradicionais da História da Educação, como a dos impressos educacionais, a partir de diferentes questões e enquadramentos teóricos, oferecendo ao campo novas perspectivas em um amplo recorte temporal. O prefácio, assinado por Vera Valdemarin, oferece um panorama dos estudos em História da Educação no Brasil, situando as contribuições apresentadas no livro.
A comparison of different methods of paper surface smoothness evaluation
Authors: Singh Surendra P.
Published: July 2023

Smoothness of paper surface is an important property from its printability. A number of techniques are available for characterizing the topographical features of the paper surface. These techniques have led to the development of smoothness testers of various types such as air-leak testers, optical contact testers, surface profilers, and a number of ink and liquid application apparatus to assess the smoothness. While all these methods are intended to serve the same purpose, they differ so greatly in their basic approach that the agreement between them cannot be taken for granted. In the present work, these methods have been applied to characterize the surface of handsheets of mechanical pulps. A comparison of these methods reveals that different methods grade these pulps differently, confirming the multidimensional nature of the surface structure and the fact that no single method is sufficient to describe it completely.
THE IMPACT OF UNIONIZATION IN THE AGRICULTURAL SECTOR: FARMER PERCEPTIONS AND BEHAVIOR
Authors: HAMZAOĞLU Nazife Merve
Published: July 2023

For centuries, agriculture has been one of the vital sectors in economic development; its role in developing economies and rural development is still inevitable. Rising food and energy prices and the negative effects of climate change can be more problematic for middle-smallholder farmers or family enterprises and low-qualified farmworkers. To overcome them, unionization and cooperatives in agriculture may present a viable option. Unionization in agriculture can be a solution for vulnerable parts of agriculture, such as workers who are exploited by working cheap and long hours and small and family businesses in a market where cooperatives are disrupted. This study focuses on the impact of unionization in the agricultural market by exploring farmer behavior. World Values Survey Data (Wave 7) was applied to reveal the factors affecting farmers' perception of the economic and social factors from different countries by segmenting union members and non-members using binomial logistic regression models. The findings show that unionized farmers have different motivations than non-members. Income targeting policies are essential to support agri-business owners.
Caminante, No Hay Camino, Se Hace Camino al Andar: On a Creative Research Project in Urban Planning
Authors: Matthey Laurent , Gaberell Simon , Chenais Alice , Rudler Jade , Seigne Aude , Subilia Anne-Sophie , Vuataz Daniel , Ruf Matthieu
Published: July 2023

This article looks back at a creative research project conducted in Geneva, Switzerland, which, by experimenting between art and science, sought to understand how citizen narratives can participate in the making of an urban plan. The approach presented here brought together geographers, architects, and novelists. Citizen narratives produced at writing workshops imagined the city of the future in ways that significantly contrasted with visions gathered from events organised by public authorities. These narratives were taken up by the novelists, who helped produce a piece of fiction containing the power to reveal the qualities of the present. This piece has since become a novel. By discovering what their future city could be, participants in this project were led to identify the places that should be preserved. Their narratives thus helped identify an ordinary heritage that could be included in an urban planning document. This reflective look at a project that gradually took shape could be useful to anyone wishing to conduct creative research in urban planning, particularly from the perspective of a more inclusive city.
Udział Polaków w formowaniu południowoafrykańskiej Kolonii Przylądkowej
Authors: Kowalski Mariusz
Published: July 2023

Udział Polaków w kolonizowaniu i zagospodarowywaniu Kolonii Przylądkowej nie jest powszechnie znany. Tymczasem Polacy pojawiali się w niej od samego początku jej istnienia (1652 r.). Przez prawie cały badany okres obecność ta była wynikiem silnych więzów gospodarczych wiążących Polskę z Niderlandami. Pod koniec tego okresu nastąpił wzrost ich udziału w związku z obecnością w Kolonii licznych obcych jednostek wojskowych, w których służyli Polacy. Wielu przybyszów z Polski osiedliło się w Południowej Afryce na stałe, założyło rodziny, a ich potomstwo weszło w skład miejscowego społeczeństwa. Pod panowaniem brytyjskim, w wyniku dwóch fal kolonizacji, osiedlili się kolejni przybysze z Polski, niejednokrotnie przybywając całymi rodzinami. Świadectwem tego zjawiska są dzisiejsze rodziny afrykanerskie: Ankiewicz, Aproskie, Beirowski, Drotsky, Hohowsky, Jankowitz, Jewaskiewitz, Kitshoff, Kolesky, Latsky, Masuriek, Troskie, Waberski, Zowitsky itd. Pobieżne obliczenia wskazują, że osadnicy z Polski stanowili nieco ponad 1% przodków dzisiejszych Afrykanerów. Polacy brali również udział w pionierskich przedsięwzięciach na odległych pograniczach Kolonii, w tym w wyprawie łupieżczo-handlowej z 1702 r.
Formulation and Sensory Attributes of the Pickle Made from Buttermilk Treated Green Chilli (Capsicum annuum)
Authors: . Saroj , Upadhyay Ashutosh , Shukla Shruti , Kumar Nishant
Published: July 2023

Background: The present study aims was to investigate the effect of Direct Vat Set buttermilk (DVSBM) and homemade buttermilk (HMBM) culture on physico-chemical properties of green chilli pickle. Methods: In the present study the effect Direct Vat Set buttermilk (DVSBM) and homemade buttermilk (HMBM) culture on physicochemical properties of green chillies pickles after 3 months of storage at ambient temperature (25±3°C). Result: The results revealed that the treatment of chillies with buttermilk i.e. HMBM and DVSBM, significantly influenced the properties of green chilli pickle. Therefore, the green chilli pickle treated with HMBM culture maintained higher acidity (0.58%) and lower pH (4.35) with higher retention of firmness and overall acceptability.
Morphological and Morphometrical Studies on the Radius and Ulna of Indian Elephant (Elephas maximus indicus)
Authors: Kapadnis P.J. , Gupta S.K. , Karmore S.K. , Jatav G.P. , Shukla B.P.
Published: July 2023

Background: The fore and hind limbs of the elephant are arranged in an almost vertical position under the body, similar to a pillar or leg of a table rather than being in the angular position seen in many other quadruped mammals to support great weight. The aim of this study was to elucidate the morphological and morphometrical outline on the radius and ulna in Elephants, thereby making more contribution in filling the gap of knowledge and skills framework in this field. Methods: For the present study, the materials from three Indian elephants were used. Some of the specimens were available at the Department of Veterinary Anatomy, Mhow. Few skeletons were dug out from the ground which was buried from the last 5-10 years in the premises of college. Result: The radius was situated obliquely in the anterior aspect of forearm region. Radius had two extremities proximal and distal extremity and a shaft. The distal end of the radius was thick, flattened and slightly prismatic in shape. The ulna was more massive than radius. It had two extremities and a body.
Não sou coveiro
Authors: Silva Graziele Iaronka da , Michaelsen Martina Belotto , Rosa Ana Paula da
Published: July 2023

Neste artigo observamos as apropriações construídas a partir da fala do presidente Jair Bolsonaro no episódio, aqui intitulado como "coveiro", em que ele se refere ao número de mortes da covid-19. O propósito é investigarmos como são construídos os sentidos a partir da circulação do discurso do presidente e das tensões sociais que emergem de sua fala. Para tanto, tomamos como método o movimento de seguir os rastros da circulação a partir de uma ênfase na semiologia discursiva. O corpus de análise é composto por reportagens jornalísticas e publicações de atores sociais em redes digitais. Nosso aporte teórico é direcionado a reflexões sobre imagem, midiatização, apropriações e circuitos, com o intuito de mostrar a dinâmica da circulação de sentidos.
A Model for the Dissemination of Circulating Tumour Cell Clusters Involving Platelet Recruitment and a Plastic Switch between Cooperative and Individual Behaviours
Authors: Hapeman Jorian D. , Carneiro Caroline S. , Nedelcu Aurora M.
Published: July 2023

Background: As cancer progresses, cells acquire traits that allow them to disperse and disseminate to distant locations in the body – a process known as metastasis. While in the vasculature, these cells are referred to as circulating tumour cells (CTCs) and can manifest either as single cells or clusters of cells (i.e., CTC clusters), with the latter being the most aggressive. The increased metastatic potential of CTC clusters is generally associated with cooperative group benefits in terms of survival, such as increased resistance to shear stress, anoikis, immune attacks and drugs. However, the adoption of a group phenotype poses a challenge when exiting the vasculature (extravasation) as the large size can hinder the passage through vessel walls. Despite their significant role in the metastatic process, the mechanisms through which CTC clusters extravasate remain largely unknown. Based on the observed in vivo association between CTC clusters and platelets, we hypothesized that cancer cells take advantage of the platelet-derived Transforming Growth Factor Beta 1 (TGF-β1) – a signalling factor that has been widely implicated in many aspects of cancer, to facilitate their own dissemination. To address this possibility, we evaluated the effect of exogenous TGF-β1 on an experimentally evolved non-small lung cancer cell line that we previously developed and used to investigate the biology of CTC clusters. Results: We found that exogenous TGF-β1 induced the dissociation of clusters into adherent single cells. Once adhered, cells released their own TGF-β1 and were able to individually migrate and invade in the absence of exogenous TGF-β1. Based on these findings we developed a model that involves a TGF-β1-mediated plastic switch between a cooperative phenotype and a single-celled stage that enables the extravasation of CTC clusters. Conclusions: This model allows for the possibility that therapies can be developed against TGF-β1 signalling components and/or TGF-β1 target genes to suppress the metastatic potential of CTC clusters. Considering the negative impact that metastasis has on cancer prognosis and the lack of therapies against this process, interfering with the ability of CTC clusters to switch between cooperative and individual behaviours could provide new strategies to improve patient survival.
Setting Research Priorities for Effective Climate Change Management and Policymaking: A Delphi Study in Bolivia and Paraguay
Authors: Marques Jorge , Guillo Mario , Bas Enric , Ramazanova Makhabbat , Albuquerque Helena
Published: July 2023

The main purpose of this article is to identify key areas of research on climate change in the context of the SDGs, focusing on the potential development impacts on Bolivia and Paraguay. Application of the Delphi technique with the involvement of a panel of experts allowed the consolidation of different perspectives and knowledge on climate change, focusing on those that experts considered to have the greatest potential impact on the regions. The results of this study constitute a valuable guide for decision-makers and funding bodies, highlighting research areas that could have a significant impact at the national and regional levels, as well as for researchers, identifying specific research areas crucial for regional development and climate change mitigation.