bluuebunny/crossref_metadata_2025 huggingface dataset:
Dispositivo intrauterino e doença inflamatória pélvica: uma real associação?
Authors: Fernandes Bruna Teles , Oliveira Lorena Beatriz Lopes de , Pupin Marina Mateus , Miguel Licério
Published: June 2022

O dispositivo intrauterino (DIU) é um método contraceptivo reversível, elegível para diversos tipos de pacientes e condições clínicas, de acordo com a Organização Mundial de Saúde (OMS). A doença inflamatória pélvica (DIP), infecção ginecológica que atinge o trato genital superior, transmitida por via sexual, pode estar relacionada ao método em algumas situações específicas. Este artigo de revisão destina-se a avaliar a ocorrência de DIP ligada à inserção e uso do DIU. Foi feita uma revisão da literatura, com pesquisa nas bases de dados Scielo, Pubmed e Google Acadêmico, e após a aplicação dos critérios de inclusão e exclusão, foram selecionados doze artigos científicos nacionais e internacionais, sem restrição por período. Os dados levantados demonstram que a associação entre a introdução do DIU e DIP não é frequente, e relacionam-se a alguns fatores específicos, que podem incrementar o risco de desenvolvimento da infeção de maneira independente. No tocante ao tempo de uso, pode ocorrer uma associação com rara infecção bacteriana (actinomicose), que exige propedêutica específica para investigação. Alguns testes clínicos e sorológicos podem ser empregados previamente à inserção do DIU, mas não devem limitar o seu uso e aplicação. Portanto, não se deve desestimular o uso do DIU pelo risco de infecção, pois trata-se de estratégia segura e efetiva de planejamento familiar.
Uma análise epidemiológica da leptospirose no Brasil e em Alagoas (2009-2019)
Authors: Da Silva Rocha Ana Carolyna , Torres Barbara Vitória dos Santos , Da Silva Mendonça Katiane , Santana Viviane Vanessa Rodrigues da Silva
Published: June 2022

Introdução: A leptospirose é uma doença infectocontagiosa que tem como agente etiológico a bactéria do gênero Leptospira. Transmitida através do contato com reservatórios animais, como os sinantrópicos, domésticos e selvagens, ou contato com o solo ou água contaminados com sua urina. Seu processo infeccioso agudo pode ser de difícil diagnóstico, muitas vezes sendo confundido com viroses tropicais, onde pode ser subdiagnosticada. Objetivo: Analisar os casos de leptospirose no Brasil e em Alagoas no período de 2009 a 2019. Metodologia: Trata-se de um estudo ecológico realizado a partir dos dados disponibilizados no DATASUS. Resultados: Entre os anos de 2009 a 2019 foram notificados 41.837 casos de leptospirose no Brasil, sendo 2011 o ano com maior notificação da doença. Houve predomínio no sexo masculino (79,9%), enquanto o feminino correspondeu a 20,07%. A faixa etária mais acometida foi entre 20 e 39 anos em nível nacional e de 20 a 39 anos no estado de Alagoas onde menos da metade dos indivíduos acometidos foram a óbito (10,5%). Quanto à evolução do indivíduo em cenário nacional, 34.769 (83,1%) pessoas evoluíram para a cura, enquanto 3.621 (8,6%) foram a óbito devido a leptospirose. Conclusão: A incidência dos casos de leptospirose no estado de Alagoas foi acima da média nacional, mas não foi uma diferença discrepante. Além disso, outras variáveis do estado de Alagoas analisadas neste estudo, como sexo e faixa etária, mostraram-se semelhantes a nível nacional.
Experiências de adaptação ao novo modelo de ensino do curso de Enfermagem em um ano de pandemia de COVID-19
Authors: Degani Glaucia Costa , Giuntini Patricia Bodnar , Machado Juliana Pereira , Dalri Cristina Camargo , Kawata Lauren Suemi , Silva Magda Fabri Isaac , Masella Tania Aparecida Cancian
Published: June 2022

Introdução: A pandemia de COVID-19 demandou adaptações no processo de formação acadêmica de enfermagem dos cursos presenciais, em virtude dos períodos de distanciamento social e das medidas restritivas. Objetivo: descrever as experiências de adaptação ao novo modelo de ensino do curso de enfermagem de um centro universitário privado em um ano de pandemia de COVID-19. Metodologia: Relato de experiência a partir das adaptações realizadas no escopo de atuação docente no contexto das aulas teóricas, atividades práticas e de extensão, estágio supervisionado e da coordenação do curso de enfermagem - presencial, do dia 16 de março de 2020 a 20 de março de 2021. Resultados: As aulas teóricas adaptaram a estrutura física para utilização de recursos tecnológicos; as atividades práticas foram suspensas, posteriormente repostas e retornaram primeiro com o estágio supervisionado; atividades de extensão foram desenvolvidas. Conclusão: As experiências do corpo docente do curso de enfermagem de um centro universitário privado permitiram vivenciar novas possibilidades de metodologias de ensino e atividades de extensão, mas também o enfrentamento de inúmeros desafios desde a reestruturação das salas de aulas, do uso do laboratório de enfermagem até o retorno das atividades nos campos de estágio, prevendo a segurança sanitária de docentes e estudantes. Tais experiências, embora permeadas por insegurança, medo e anseios, foram resultados de esforços por parte dos docentes e apoio da coordenação do curso para garantir a continuidade do ritmo das atividades e a qualidade no ensino para os estudantes.
Análise da complexidade de itens do ENADE conforme critérios da taxonomia de Bloom revisada: contribuições ao ensino de estética
Authors: Petersen Cristina Buischi , Lucca Daniela Nunes Januário de
Published: June 2022

A avaliação do Ensino Superior no Brasil tem como um de seus indicadores o Exame Nacional de Desempenho dos Estudantes (ENADE) que se estabelece como   indicador regulador da renovação do reconhecimento dos cursos de Graduação e balizador da qualidade do ensino brasileiro. O objetivo deste trabalho foi analisar 54 questões objetivas de componente específico do ENADE edições 2016 e 2019 para o Curso Superior de Tecnologia (CST) em Estética e Cosmética relacionando-as com a complexidade proposta pela Taxonomia de Bloom Revisada (TBR). Utilizou-se estudo descritivo exploratório com análise e classificação das questões na tabela bidimensional proposta pela TBR por meio das dimensões dos processos cognitivos e dimensões do conhecimento. A maioria das questões 44,5% (24) requisitaram do estudante o processo cognitivo entender seguida do lembrar 29,7% (16), aplicar 9,3% (5), analisar 11% (6) e avaliar 5,5% (3). Quanto à dimensão do conhecimento a maioria das questões avaliavam a dimensão do conhecimento efetivo 44,5% (24) seguida por conceitual 35,2% (19) e procedural 20,3% (11). Os resultados podem contribuir para a compreensão da classificação de objetivos educacionais e instrumentalizar a elaboração de planos de aprendizagem de alunos e avaliações com foco no perfil do egresso e nas competências e habilidades indicadas nas diretrizes curriculares dos cursos de graduação tecnológica.
Ferramentas interativas no ensino avícola para alunos de Medicina Veterinária
Authors: Amaral Cecilia Maria Costa do , Silva Ketherson Rodrigues , Lima Andréa Cristina Frizzas de
Published: June 2022

Atualmente o Brasil ocupa a primeira posição como país exportador e terceira posição como produtor, no ranking mundial da carne de frango. No segmento de postura, também demonstra relevância, produzindo aproximadamente 53 bilhões de ovos em 2020, portanto, a cadeia avícola apresenta-se como uma importante rede de oportunidades para a atuação do médico veterinário. Sendo assim, o objetivo do presente estudo foi apresentar algumas ferramentas interativas, como os plugins H5P®: Find the words, Advental calendar, Flashcard, Quiz (question set), Column - drag text, Fill in the blanks e Memory game, presentes na plataforma Moodle - AVA Institucional do Centro Universitário “Barão de Mauá”, além de um modelo anatômico de galinha (4D Vision - 4D Master®) para estudar a anatomia das aves. O modelo anatômico permite a remoção e remontagem das estruturas anatômicas a fim de relembrar a organização dos sistemas orgânicos de uma galinha (Gallus gallus). As atividades apresentadas no presente estudo começaram a ser elaboradas em 2019 e estão sendo inseridas nas disciplinas da área de Produção Animal e Ornitopatologia do curso de Medicina Veterinária do Centro Universitário “Barão de Mauá”. Desde então foi possível perceber grande entusiasmo, empenho e motivação dos alunos na realização das atividades propostas, entretanto, sugere-se estudos futuros para avaliação mais detalhada desses resultados. Como conclusão verificou-se que os plugins do H5P® e o modelo anatômico apresentados no estudo, permitiram inserir uma grande variedade de assuntos presentes nos conteúdos programáticos das disciplinas, de forma simples e prática. Além disso, forneceu feedback imediato aos discentes, intercalou atividades e diversificou metodologias de ensino promovendo facilidade, motivação, incentivo a criatividade e melhoria da concentração e consequentemente, do processo de aprendizagem.
Arte de Pensar: investigações sobre os percursos da Lógica
Authors: Machado Clarice Rosa
Published: June 2022

Neste estudo, pretendo apresentar um esboço histórico da lógica, construído ao colocar em evidência alguns aspectos da formação do pensamento humano que propiciaram o seu desenvolvimento, partindo da necessidade humana do bem pensar. O estudo foi realizado por meio da vertente teórico-metodológica da Análise Crítica do Discurso (ACD) de Norman Fairclough (2001) e da Análise de Conteúdo (AC) de Laurence Bardin (2010), tomando como pressuposto a concepção do texto verbal como materialidade discursiva e o discurso como a plenitude da prática social que o abrange e constitui (FAIRCLOUGH, 2001). De maneira transversal, a lógica era vista como a arte de pensar e o seu ensino realizava-se através de reflexões e discussões cotidianas, em outras palavras, o ensino da lógica não se limitava a uma exposição histórico-didática da lógica tradicional, porém, visava a formar bem a mente dos estudantes, orientando o intelecto na busca da verdade.A lógica é importante tanto como instrumento de análise de argumentos, quanto do ponto de vista histórico, porque ela foi inventada e sistematizada dentro de um contexto da Filosofia Grega, e, portanto, está aliada à história do pensamento ocidental. O ensino de lógica se faz necessário atualmente porque ela oferece ferramentas que permitem interpretar as informações que chegam até os sujeitos e perceber que elas não representam todas as realidades existentes, então não se pode moldar comportamentos, pensamentos e disseminar essas informações sem uma análise crítica, racional e cuidadosa.
Classical Musicians v. Copyright Bots
Authors: Berkowitz Adam
Published: June 2022

The COVID-19 pandemic forced classical musicians to cancel in-person recitals and concerts and led to the exploration of virtual alternatives for engaging audiences. The apparent solution was to livestream and upload performances to social media websites for audiences to view, leading to income and a sustained social media presence; however, automated copyright enforcement systems add new layers of complexity because of an inability to differentiate between copyrighted content and original renditions of works from the public domain. This article summarizes the conflict automated copyright enforcement systems pose to classical musicians and suggests how libraries may employ mitigation tactics to reduce the negative impacts when uploaders are accused of copyright infringement.
Research on Knowledge Organization of Intangible Cultural Heritage Based on Metadata
Authors: Qing Fan , Tan Guoxin , Sun Chuanming , Chen Panfeng
Published: June 2022

Metadata has been analyzed and summarized. Based on Dublin Core metadata, combined with the characteristics and forms of intangible cultural heritage, this article explores the metadata for intangible cultural heritage in knowledge organizations based on relevant resource description standards. The Wuhan woodcarving ship model is presented as an example of national intangible cultural heritage to control the application of metadata in intangible cultural heritage knowledge organizations. New ideas are provided for the digital development of intangible cultural heritage.
Flow of Resources in a Changing World
Authors: Hansen Jesper , Dam Peder , Bjerregaard Mikael Manøe , Jouttijärvi Arne
Published: June 2022

The influx of prestigious foreign objects into Southern Scandinavia throughout the Iron Age and Viking Age is well-documented. For example, Roman or Frankish luxury objects would find their way north via trade or through dynastic gift exchanges as part of a conspicuous elite culture.

Access to crucial raw materials has in many ways been formative for both prehistoric and historic societies. The availability – or lack thereof – of specific resources could determine technological developments, and the need for nonlocal raw materials could shape evolving networks. For prehistoric and early historic times in Southern Scandinavia, the written sources and typological studies have limited value in determining the provenance of various raw materials. A typological deduction based on design can indicate the area of production for certain artefacts, but the raw materials used might originate from elsewhere. Based on scientific methods, this study sets out to map and analyse the geography of the available provenances of materials used in archaeological objects. From where did the raw materials found in Southern Scandinavia originate?  Was there a connection between the flow of raw materials and the political situation?
Bibliotekarer som aktivister i Danmark og Sverige
Authors: Nissen Anne-Sofie Elbrønd , Kann-Rasmussen Nanna
Published: June 2022

This article concerns differences in the types of conflicts related to librarians acting as activists in Denmark and Sweden. The conflicts in Denmark are limited and mainly of internal character while the conflicts in Sweden are debated in more broadly in the field.
Through the Orders of Worth framework by Boltanski & Thévenot the article analyses interviews with both Danish and Swedish librarians. The analysis shows that activism in Denmark is considered an appropriate description for library work that involves doing more than making materials available in working towards social justice. In Sweden, the understanding of activism is more problematic and the Swedish informants in the article do not see themselves as activists, nor the library’s work for social justice as activism. The article shows that Danish librarians work strategically with activism through partnerships. In contrast, the Swedish librarians justify their work by focusing on work done for the good of society or certain groups, since this is considered the best possible position in order to avoid conflict, as the library institution itself also is justified from this perspective. Finally, the article discusses the cultural policy-climate in both countries and shows, that libraries and the cultural field in general have been low on society’s agenda in Denmark, while there is an ongoing ideological conflict in Sweden between left- and rightwing political actors and between national and local levels of government. Overall, the article shows that the difference in the conflicts related to activism in libraries in Denmark and Sweden must take the cultural policy climate in each country in to account, but that it is important for the understanding of the conflict to discuss how actors justify their work for social change.
Book review: New health information literacies
Authors: Sundin Olof
Published: June 2022

Book review of Anna-Maija Multas (2022) New health information literacies. A nexus analytical study, Acta universitatis Ouluensis B Humaniora 192, University of Oulu, Oulu
Language technology research bibliography for Lithuanian 2016–2020
Authors: Utka Andrius , Vaičenonienė Jurgita , Briedienė Monika , Krilavičius Tomas
Published: June 2022

The language technology bibliography for Lithuanian language in the period 2016-2020. The resource is in BibTex format and it contains: 1) 91 references of research publications, 2) 15 references of documents and strategies, and 3) 26 references of language resources and tools. The resource is used for the paper: Utka, Andrius, Jurgita Vaičenonienė, Monika Briedienė and Tomas Krilavičius. 2020. Development and Research in Lithuanian Language Technologies (2016-2020). In Human language technologies - the Baltic perspective : proceedings of the 9th international conference, Baltic HLT 2020, Kaunas (Lithuania). Amsterdam : IOS Press.
Biophysical Kv3 channel alterations dampen excitability of cortical PV interneurons and contribute to network hyperexcitability in early Alzheimer’s
Authors: Olah Viktor J , Goettemoeller Annie M , Rayaprolu Sruti , Dammer Eric B , Seyfried Nicholas T , Rangaraju Srikant , Dimidschstein Jordane , Rowan Matthew JM
Published: June 2022

In Alzheimer’s disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with progressive neuropathology, yet disruptions in circuit activity emerge before their deposition in AD models and patients. Parvalbumin (PV) interneurons are potential candidates for dysregulating cortical excitability as they display altered action potential (AP) firing before neighboring excitatory neurons in prodromal AD. Here, we report a novel mechanism responsible for PV hypoexcitability in young adult familial AD mice. We found that biophysical modulation of Kv3 channels, but not changes in their mRNA or protein expression, were responsible for dampened excitability in young 5xFAD mice. These K+ conductances could efficiently regulate near-threshold AP firing, resulting in gamma-frequency-specific network hyperexcitability. Thus, biophysical ion channel alterations alone may reshape cortical network activity prior to changes in their expression levels. Our findings demonstrate an opportunity to design a novel class of targeted therapies to ameliorate cortical circuit hyperexcitability in early AD.
An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37
Authors: Kolesinski Piotr , Wang Kuei-Chen , Hirose Yujiro , Nizet Victor , Ghosh Partho
Published: June 2022

Surface-associated, coiled-coil M proteins of Streptococcus pyogenes (Strep A) disable human immunity through interaction with select proteins. However, coiled coils lack features typical of protein–protein interaction sites, and it is therefore challenging to understand how M proteins achieve specific binding, for example, with the human antimicrobial peptide LL-37, leading to its neutralization. The crystal structure of a complex of LL-37 with M87 protein, an antigenic M protein variant from a strain that is an emerging threat, revealed a novel interaction mode. The M87 coiled coil unfurled and asymmetrically exposed its hydrophobic core to capture LL-37. A single LL-37 molecule was bound by M87 in the crystal, but in solution additional LL-37 molecules were recruited, consistent with a ‘protein trap’ neutralization mechanism. The interaction mode visualized crystallographically was verified to contribute significantly to LL-37 resistance in an M87 Strep A strain and was identified to be conserved in a number of other M protein types that are prevalent in human populations. Our results provide specific detail for therapeutic inhibition of LL-37 neutralization by M proteins.
Vision-related convergent gene losses reveal SERPINE3’s unknown role in the eye
Authors: Indrischek Henrike , Hammer Juliane , Machate Anja , Hecker Nikolai , Kirilenko Bogdan , Roscito Juliana , Hans Stefan , Norden Caren , Brand Michael , Hiller Michael
Published: June 2022

Despite decades of research, knowledge about the genes that are important for development and function of the mammalian eye and are involved in human eye disorders remains incomplete. During mammalian evolution, mammals that naturally exhibit poor vision or regressive eye phenotypes have independently lost many eye-related genes. This provides an opportunity to predict novel eye-related genes based on specific evolutionary gene loss signatures. Building on these observations, we performed a genome-wide screen across 49 mammals for functionally uncharacterized genes that are preferentially lost in species exhibiting lower visual acuity values. The screen uncovered several genes, including SERPINE3, a putative serine proteinase inhibitor. A detailed investigation of 381 additional mammals revealed that SERPINE3 is independently lost in 18 lineages that typically do not primarily rely on vision, predicting a vision-related function for this gene. To test this, we show that SERPINE3 has the highest expression in eyes of zebrafish and mouse. In the zebrafish retina, serpine3 is expressed in Müller glia cells, a cell type essential for survival and maintenance of the retina. A CRISPR-mediated knockout of serpine3 in zebrafish resulted in alterations in eye shape and defects in retinal layering. Furthermore, two human polymorphisms that are in linkage with SERPINE3 are associated with eye-related traits. Together, these results suggest that SERPINE3 has a role in vertebrate eyes. More generally, by integrating comparative genomics with experiments in model organisms, we show that screens for specific phenotype-associated gene signatures can predict functions of uncharacterized genes.
Using population selection and sequencing to characterize natural variation of starvation resistance in Caenorhabditis elegans
Authors: Webster Amy K , Chitrakar Rojin , Powell Maya , Chen Jingxian , Fisher Kinsey , Tanny Robyn E , Stevens Lewis , Evans Kathryn , Wei Angela , Antoshechkin Igor , Andersen Erik C , Baugh L Ryan
Published: June 2022

Starvation resistance is important to disease and fitness, but the genetic basis of its natural variation is unknown. Uncovering the genetic basis of complex, quantitative traits such as starvation resistance is technically challenging. We developed a synthetic-population (re)sequencing approach using molecular inversion probes (MIP-seq) to measure relative fitness during and after larval starvation in Caenorhabditis elegans. We applied this competitive assay to 100 genetically diverse, sequenced, wild strains, revealing natural variation in starvation resistance. We confirmed that the most starvation-resistant strains survive and recover from starvation better than the most starvation-sensitive strains using standard assays. We performed genome-wide association (GWA) with the MIP-seq trait data and identified three quantitative trait loci (QTL) for starvation resistance, and we created near isogenic lines (NILs) to validate the effect of these QTL on the trait. These QTL contain numerous candidate genes including several members of the Insulin/EGF Receptor-L Domain (irld) family. We used genome editing to show that four different irld genes have modest effects on starvation resistance. Natural variants of irld-39 and irld-52 affect starvation resistance, and increased resistance of the irld-39; irld-52 double mutant depends on daf-16/FoxO. DAF-16/FoxO is a widely conserved transcriptional effector of insulin/IGF signaling (IIS), and these results suggest that IRLD proteins modify IIS, although they may act through other mechanisms as well. This work demonstrates efficacy of using MIP-seq to dissect a complex trait and it suggests that irld genes are natural modifiers of starvation resistance in C. elegans.
Greening the Curriculum: A Strategic Waste Management for Chemical Wastes in School Laboratories
Authors: Valenzuela Jacqui Lou Baguios , Blancaflor Marilyn M. , Solatorio Cynde Rose S. , Anata Edwin T. , Salubre Juliet
Published: June 2022

Despite global awareness on the effects of improper chemical waste disposal, the actual practice of proper waste handling is still neglected. Serving as the best venue for information dissemination, schools can reinforce waste management programs through its curriculum. Identification of curriculum areas that can complement waste management strategies by evaluating the level of awareness and participation of its teaching employees, non-teaching staff, and students is the main objective of this study.  Validated self-constructed survey-questionnaires were administered to 149 respondents representing the total population of the laboratory teachers, students, non-teaching employees, and researchers of the Western Institute of Technology, Philippines whose primary job deals with chemicals. The data gathered and analyzed using student t-test showed that there is no significant difference in the level of awareness among teaching and non-teaching employees in terms of the school's chemical waste management program. A significant number of senior high school students showed lack of awareness on Philippine environmental laws and the chemical waste management in school.  Employees whose primary job is not associated with teaching and research do not realize their role in chemical waste minimization. More senior high school students show environmental concern over college students, but it is the latter group that apply the concepts of chemical waste management into actual practice.
Job-Embedded Learning (JEL) and Monitoring and Evaluation Levelling (MEL): An Educator’s Aftermaths to Learning and Development Intervention (LDI)
Authors: Palanas Victorina
Published: June 2022

Teachers play a crucial role in improving the quality of the teaching and learning process. Hence, enhancing teacher quality ranks foremost in the many educational reform efforts toward quality education. (PPST, 2017). This study aims to improve the teaching-learning process as well as to increase the Mean Percentage Score (MPS) in all learning areas through Job-Embedded Learning (JEL) and Monitoring and Evaluation Levelling (MEL). Mixed-Method Research Design was used to continually ensure the conduct of open-ended techniques, which contributed to the successful implementation of Learning and Development Intervention (LDI). Data was collected and interpreted using graphical representations and Pareto Analysis. The contributing factors that help LDI successful were: Participants were given the opportunity to reinvent usual classroom routines suited to the current situation, and appropriate strategies were utilized according to the learners’ needs along with the available materials and equipment in the school. This structured JEL process requires that professionals should (a) plan to continue learning while on the job; (b) integrate their new learning with normal work activities; (c) constantly reflect upon and evaluate their work practice; (d) generate new insights and learning based on their reflections; and (e) share experiences and develop new insights with others.  Improvement of work performance based on the result of the entire learning process.
Difficulties Encountered In the Conduct of Student Researches
Authors: Micabalo Kingie , Cano Jesszon , Montilla Ryan , Tan Arsenio Robert , Navarro June Ace
Published: June 2022

Research is a mission for trust with the assistance of study, acknowledgment, association, and preliminaries in the journey for information through the goal and proficient methodology to discover answers for an issue. The examination decides and breaks down the degree of appraisal seen by the understudies regarding the complexity and significance of the research. The examination respondents were the 252 understudies from Marketing and Human Resource Management courses utilizing the descriptive survey method as a research instrument on a simple random sampling. Frequency and simple percentages, and Mode were used to summarize, separate, and unravel the information. The discovery uncovered that understudies perceived the importance of research undertakings. However, the investigation revealed that acquainting with different investigations in regions identified with research is a complex thing during the proposal. Ampleness of information in estimating apparatuses (insights) to evaluate and examine research information is the complex part of conducting the research. Lastly, introducing thoughts intelligently, legitimately, plainly, and carefully is the complex part of writing the research paper. The study concluded that constructive alignment between teaching and learning in the proposal stage, conducting the research, and writing the paper must be practiced to ensure the stronger realization of students’ journey and output in doing research.
Saving Angels Program: An Intervention for Students at Risk of Dropping Out (A Community of Practice Action Research)
Authors: Yocampo Joanna Marie
Published: June 2022

The Department of Education and the Schools Division of Camarines Sur, in its support to the mission and vision of the department to keep students in school, Bagacay National High School came up with the Saving Angels program, a community of practice for excellent school’s project that addressed the Students-at-risk-of-Dropping out. The Saving Angels initiative looked into the dropout rate of the school, the level of effectiveness of the program, and its effect on the dropout rate. The research followed a descriptive-quantitative design where the level of effectiveness was taken from a survey questionnaire, whereas the dropout rate was computed at the end of each quarter. The interventions conducted in this study are Teacher’s Bank, Model Class, Hiking Society, Gulayan sa Bawat Bagacayenong Tahanan, and Ambassadors of Academic Instruction. These interventions targeted the generation of instructional materials, classroom modification and attendance monitoring, student home visitation, open vegetable garden, and teacher leaders and heroes in instruction. A learning action cell served as the backbone of the sharing. The said interventions were conducted from June 2018 to February 2019. The program resulted in a decrease of the school dropout rate from 10.43% (52 students) in 2016-2017, 3.2% (20 from 623) in 2017-2018, to only 2.8% (20 out of 717) of 2018-2019. The program continues and grows to sustain the development of the Bagacañeno learners.
Exploring the Level of Grade 7 Students' Reading Proficiency in Comparison to the Norm
Authors: Dunuan Kim Dilla , Timoteo Andrew , Galvan Kristine Joie
Published: June 2022

Reading comprehension requires specific skills, and improving it entails the collective efforts of the school, teachers, and students. Schools use various assessments to measure students' reading skills to ensure that students are at par with their grade level. This study ascertains the reading proficiency level of 232 Grade 7 students in an international school in Cambodia. The researchers used a quantitative method, and data from the Measure of Academic Progress Test were gathered through the Rasch Unit Scale. The participants are the whole population of grade 7. Furthermore, data were analyzed through arithmetic mean and standard deviation to assess students' proficiency level and identify the goal that should be prioritized for improvement. The results reflected that the majority of the students did not achieve the norm grade level mean Rasch Unit. Moreover, from the five goals, Literary Text: Language, Craft, and Structure should be improved the most. The findings of this study suggest improving all five reading goals with Literary Text: Language, Craft, and Structure as the main priority. Consequently, the results provided significant implications to the school in developing enrichment programs tailored to address the reading goals, teachers in terms of teaching strategies and differentiation, and students preparing for their Advanced Placement course.
Problem-Solving Skills of Students in Electrochemistry Using a Flipped Classroom Model
Authors: Necor Dexter
Published: June 2022

The pedagogical practice of the flipped classroom model (FCM) was undertaken to determine the students' problem-solving skills in electrochemistry. A quasi-experimental design was used in this study using two contrasted groups, experimental group (flipped classroom) and control group (conventional classroom). The freshmen civil engineering students were the respondents of the study. Five factors of problem-solving skills were used as a scheme interpretation of student's answers such as (a) Problem Comprehension; (b) Understanding Relationships Among Chemical Concepts; (c) Understanding Associated Chemical Concepts (d) Applying Appropriate Problem-Solving Strategies; and (e) Using Appropriate Mathematics.    Results revealed that student’s under the flipped class was of better problem comprehension and can relate chemical concepts to the problem than the conventional class. Most of the students can do mathematical calculations in both groups but failed to explain the underlying concepts. Many students have many misconception statements on the oxidizing-reducing agents and the flow of electrons in the anode to cathode. The spontaneity of the cell was also the least understood. Nonetheless, many students can solve the standard and non-standard Ecell potential and Gibbs free-energy (?Gº). Ergo, the flipped classroom teaching is a successful teaching approach in enhancing the problem-solving skills in learning electrochemistry.
A Correlational Study on the Teaching Methodologies and the Competencies of Graduates in a Private University in the Philippines
Authors: Micabalo Kingie , Poliquit Winnie Marie , Ibanez Estela , Pabillaran Robert , Edicto Quennie Marie , Cano Jesszon
Published: June 2022

Teaching and learning methodologies are significant factors in building students’ competency after college life, making them a good contender in the labor market. The study determined the impact of the varied methodologies in teaching and learning on the graduates' competency. The 181 graduate respondents participated in the survey on a snowball method in data gathering. Frequency and simple percentage, weighted mean, Chi-Square Test of Independence, and One-way ANOVA were used to treat and interpret the data. The findings revealed that, in a pervasive way, the teaching and learning methodologies among faculties embodied in the flipped classroom, project-based learning, cooperative learning, problem-based learning, and competency-based learning in the Department were perceived by the graduates. By this instance, further findings revealed a significant relationship with adopting these varied methodologies and its influence on the graduates' competency in oral/written communications, teamwork/ collaboration, information/ technology application, leadership, and professionalism/ work ethic. The study concluded that a more substantial imposition of teaching and learning methodologies to the students' could greatly emphasize graduates' professionalism, leadership, communication, collaboration, and knowledge in information technology. Furthermore, the influence of flipped classrooms, project-based learning, cooperative learning, problem-based learning, and competency-based learning in the teaching and learning experiences in the Department provides a good impact on their competency as a graduate. These practices indicate a strong alignment between the institution's interests which focuses on producing competent and innovative graduates that are efficient and effective in the labor market.
Quantification of Haemophagocytes on Bone Marrow Aspirate Smears and its Correlation with the Clinical Outcomes- A Prospective Study
Authors: Soni Mamta , Sundaram Supraja , Kesavan Sindhuja
Published: June 2022

Introduction: Haemophagocytic Lymphohistiocytosis (HLH) is a rapidly progressive life threatening condition in which activated macrophages engulf haematopoietic cells. HLH is often overlooked because of its rarity and lack of awareness of this prevailing condition. Though previously attempts have been made to quantify hemophagocytes in marrow aspirates, to the best of present knowledge, none of the studies have correlated the number of haemophagocytes with the clinical outcomes of the patients. Aim: To study the role of laboratory parameters and number of haemophagocytes detected in bone marrow aspirates in determining the clinical outcome of the patients. Materials and Methods: This was a prospective observational study conducted in Apollo Hospitals, Chennai between November 2013 to November 2015 on 41 patients who had haemophagocytosis in bone marrow aspirates. The laboratory parameters and clinical findings of these patients were obtained and were correlated with the outcome of these patients. The role of quantification of haemophagocytes in determining the outcome of the patients was also studied. The continuous variables were expressed either as mean±Standard deviation (SD) or median, as appropriate. All the categorical variables were expressed either as percentage or in proportions. The p-value was derived using Chi-square test or Fischer’s exact test and value of <0.05 was considered significant. Results: The mean age was 49±16.1 years and was constituted by adults in majority. The occurrence was common in males (75.6%). The most common underlying cause of HLH was found to be infection [78.9%]. Mortality rate was 17.1%. It was found that laboratory parameters and number of haemophagocytes in the bone marrow aspirates had no significant association with the clinical outcome of the patients. Conclusion: The number of haemophygocytes detected do not have any impact on the clinical outcome of the patients. Also there is no significant association between abnormality of laboratory parameters and clinical outcome. An early detection of haemophagocytosis is important to aid in an early diagnosis of HLH but quantifying it has no clinical significance. Timely therapeutic interventions based on prompt reporting of haemophagocytes significantly reduces mortality, irrespective of abnormalities in other test parameters. Careful examination of the bone marrow aspirate is also important to determine the underlying condition causing HLH.
Changes in Activity of Phenylalanine Ammonia Lyase (PAL), Phenols and β 1, 3 Glucanase in Crossandra Plants affected by Fusarium incarnatum (Desm.) Sacc and treated with Bioagents, Organic Amendments, Silver Nanoparticles and Fungicide in Pot Culture
Authors: Mallaiah B. , Muthamillan M.
Published: June 2022

Laboratory and pot culture experiments were carried to study the effect of different bioagents, organic amendments, silver nanoparticles and fungicide in management of crossandra wilt caused by Fusarium incarnatum and nematode Pratylenchus. delattrei During the study observations are made on changes in activity of phenylalanine ammonia lyase (PAL), phenols and β 1, 3 Glucanase in crossandra plants. All the treatments applied recorded increased levels of phenylalanine ammonia lyase (PAL), phenols and β 1, 3 Glucanase in treated plants, but among all soil application (SA) of T.viride @ 2.5 kg/ha at 20 DAP plus soil drenching (SD) of carbendazim @ 0.1% at 30 DAP plus SA of T.viride @ 2.5 kg/ha at 50 DAP plus Foliar application (FA ) of P. fluorescens@ 1.0 kg/ha at 70 DAP plus Foliar application (FA ) of B. subtilis @ 1.0 kg /ha at 90 DAP was found to be significantly higher in induction of phenylalanine ammonia lyase (PAL), phenols and β 1, 3 Glucanase in crossandra. The same results are also noticed in later stage in reducing disease incidence compare to control and other treatments.
Pre-sowing Seed Treatment of Chemicals, Botanicals, Plant Growth Regulators on Growth, Yield and Yield Attributing Traits of Linseed (Linum usitatissimum L.) under Late Sowing Conditions var. Uma
Authors: Ananthwar Pratik , Dayal Abhinav , Rai Prashant Kumar , Thomas Neha , Jain Prashant Ankur
Published: June 2022

The experiment was conducted at Field Experimentation and Farm Research Centre, Department of Genetics and Plant Breeding, (Rabi season, 2020-21) Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj (U.P.). The experimental material for present experiment comprised of thirteen priming treatments on linseed seed. The experiment was conducted in Randomized Block Design (RBD) with three replications. Linseed seeds of variety Uma was subjected to various pre sowing treatments like MnSO4,FeSO4 Pongamia leaf powder, Arappu leaf powder, Notchi leaf powder, Kinetin at various concentrations along with distilled water control. The study revealed that linseed seeds treated with Pongamia leaf powder T6 (5%) showed maximum field emergence (97.48%), plant height 60 days (77.46cm) and 90 days (92.69cm) no of primary branches per plant (5.97),no of seeds per capsule (8.95),no of capsules per plant (25.91), test weight (9.43), seed yield per plant (4.78g), seed yield per plot (128.4g), biological yield (8.26), harvest index (79.53) and reduced days to 50% flowering (65.89), days to maturity (115.89), followed by kinetin T12 50(ppm), in comparison to control T0.
Investigative Study of Effects of Gallus domesticus guano, Cucumeropsis mannii shell and Elaeis guineensis shell Additives on the Refractory Properties of Isiagu Clay
Authors: Ojukwu Victor E. , Igbokwe Philomena K. , Ugonabo Victor I.
Published: June 2022

This research investigated the effects of chicken dropping, melon shell and palm kernel additives on the refractory properties of Isiagu Clay. The raw materials were collected locally, processed and analysed using Scanning Electron Microscope/Energy Dispersive X-ray (SEM/EDX). The additives were added to the raw clay in the ratio of 2.5,5.0,7.5 and 10 wt% and fired at 900oC and 1100oC, respectively. The refractory properties measured were; linear shrinkage, apparent porosity and bulk density. The result of the SEM/EDX analyses showed that the clay is a fireclay since it contains 61.68% Al2O3 and 34.97% SiO2 while chicken dropping, melon shell, and palm kernel shell contained 37.41% SiO2, 84.62% P2O5, and 48.31% Nb2O5, respectively. Chicken dropping was responsible for strength, melon for toughness and palm kernel shell for conductivity. SEM/EDX morphological results showed that the clay sample contains tiny to coarse particles. The bulk density measurement confirmed the strength and toughness of melon shell, the only additive which met the international standard for refractory application. XRD analysis results showed the presence of two crystalline phases at 21.4o and 22.4o namely, quartz and calcite in the additives used which are both responsible for strength in the refractory brick. Sudden variation in properties was observed for chicken droppings due to the presence of a reasonable amount of P2O5. From the study, melon shell and palm kernel shell are suitable for refractory brick production and further studies are recommended for chicken dropping. ANOVA results confirmed that for melon shell and apparent porosity only temperature was significant.
Effect of Vibratory Inhibition and Pelvic Stabilization Exercise on Tone, Balance and Gross Motor Function in Spastic Cerebral Palsy- A Comparative Study
Authors: Gupta Nehal , Kumar Saurabh , Gupta Aarti , Rishi Priyanka
Published: June 2022

Objectives: Cerebral palsy is one of the leading causes of movement and posture disorders. Recently, Vibration therapy as a treatment method in clinical practice has been used as a complementary approach. This study compared the effects of Segmental Muscle Vibration and Pelvic Stabilization Exercises on Muscle Tone, Balance, and Gross Motor Function in spastic CP children.

Materials and Methods: A total of 20 children with Spastic Cerebral Palsy, of both sexes (age range of 4-6 years) were included in the study. The Children were assigned into two groups.  Group A received Segmental Muscle Vibration along with conventional treatment i.e. Passive Stretching Exercise and Group B received Pelvic Stabilization Exercise along with conventional treatment for 40 minute, 3 times a week for 3 weeks. Outcome measures include Modified Ashworth Scale, Pediatric Balance Scale and Gross Motor Function Measure-88 for measuring Tone (spasticity), Balance and Gross Motor Function.

Results: A significant improvement in all variables (p < 0.05) was observed in each group, with greater improvement in tone, balance and gross function indices in group A.

Conclusion: From the results we concluded that both the Segmental Vibration Inhibition Therapy and Pelvic Stabilization exercise yielded a clinically significant improvement in spastic CP; but Segmental Vibration Inhibition Therapy shows more improvement in reduction in tone, improvement in balance and gross motor function.
Photodegradation of Rhodamine-B Dye under Natural Sunlight using CdO
Authors: Lavate Dipali , Sawant Vikas , Khomane Ashok
Published: June 2022

The present study includes synthesis of CdO thin film by simple and cost effective chemical bath deposition method. Cadmium monochloroaceatate were used for preparation of CdO thin film.  The structural, optical properties of CdO thin film were investigated with the help of X-ray diffraction (XRD) and UV-Vis NIR double beam spectrometry. The XRD studies revealed that annealed thin film shows crystalline in nature having 48.4 nm in size. The optical band gap of thin film was found to be 2.13 eV. Scanning Electron Microscopy (SEM) images shows sphere like structure which is closely arranged with each other. The presence of functional group was confirmed by Fourier Transform Infra Red (FTIR). Brunauer–Emmett–Teller (BET) surface area analysis confirm formation of a mesoporous CdO with 6.01 m2/g surface area and 31.96 nm average pore diameter. The photocatalytic activity of prepared thin film was checked by using Rhodamine-B as a model dye under natural sunlight and found to be 48%. Copyright © 2022 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
The voltage‐dependent K+ channel (Kv1.5) cloned from rabbit heart and facilitation of inactivation of the delayed rectifier current by the rat β subunit
Authors: Sasaki Yoshiteru , Ishii Kuniaki , Nunoki Kazuo , Yamagishi Toshio , Taira Norio
Published: July 2002

We have isolated a cDNA coding for a delayed rectifier K+ channel (RBKV1.5) from rabbit heart. The amino acid sequence of RBKV1.5 displays a homology to that of other K+ channels of Kv1.5 class. Overall amino acid identity between RBKV1.5 channel and Kv1.5 channel of other species is about 85%. RNA blot analysis revealed the expression of the primary transcript in various rabbit tissues, at the highest level in both the atrium and ventricle. When expressed in Xenopus oocytes, RBKV1.5 current showed a delayed rectifier type characteristics, which was converted to rapidly inactivating currents upon coexpression with a β subunit.
Comparison of the specificities of p70 S6 kinase and MAPKAP kinase‐1 identifies a relatively specific substrate for p70 S6 kinase: the N‐terminal kinase domain of MAPKAP kinase‐1 is essential for peptide phosphorylation
Authors: Leighton Ian A. , Dalby Kevin N. , Barry Caudwell F. , Cohen Patricia T.W. , Cohen Philip
Published: July 2002

xxR/KxRxxSxx sequences were phosphorylated with high efficiency by both p70 S6 kinase (p70S6K) and MAPKAP kinase‐1. The best substrate for MAPKAP kinase‐1 (KKKNRTLSVA) was phosphorylated with a K
m of 0.17 μM, and the best substrate for p70S6K (KKRNRTLSVA) with a K
m of 1.5 μM. The requirement of both enzymes for Arg/Lys at position n‐5 could be partially replaced by inserting basic residues at other positions, especially by an Arg at n ‐ 2 or n ‐ 4. MAPKAP kinase‐1 (but not p70S6K) tolerated lack of any residue at n ‐ 5 if Arg was present at n ‐ 2 and n ‐ 3. p70S6K (but not p90S6K) tolerated Thr at position n and absence of any residue at n + 2. The peptide KKRNRTLTV, which combined these features, was relatively selective for p70S6K having a 50‐fold higher V
max/K
m than MAPKAP kinase‐1. Inactivation of the N‐terminal kinase domain of MAPKAP kinase‐1, which is 60% identical to p70S6K, abolished activity towards all peptides tested, but the enzyme retained 30–40% of its activity if the C‐terminal kinase domain was inactivated.