bluuebunny/crossref_metadata_2025 huggingface dataset:
An outbreak of systemic intoxication with irritant contact dermatitis due cypermethrin in dairy cows - case report
Authors: Marcom N.N. , Mendonça C.L. , Souza M.I. , Costa N.A. , Afonso J.A.B. , Zache E. , Almeida A.P. , Santos D.O. , Santos R.L. , Arenales A.
Published: August 2022

ABSTRACT Pyrethroids are ectoparasiticides safe for mammals and widely used in farm animals. An outbreak of systemic intoxication with irritant contact dermatitis resulting from the use of cypermethrin pour on in dairy cows is reported in the state of Pernambuco. Eight adult animals were affected, three died on the property and five were referred to the Clínica de Bovinos, Universidade Federal Rural de Pernambuco, Campus Garanhuns. These received 100 mL of pour on Cypermethrin (Ectonil ®, Cipermetrina, Labgard, Brasil). Apathy, hyperexcitability, muscle tremors, sialorrhea, bradycardia and crusted lesions were observed on the dorsum of the neck, scapula, ears and ulcerations in the oral and vaginal mucosa. There was hyperfibrinogenemia and leukocytosis due to neutrophilia with a regenerative left shift. Histopathology showed areas of erosion and ulceration of the epidermis and perivascular lymphohistiocytic and neutrophilic infiltrate in the superficial dermis. Supportive treatment was done with improvement of systemic signs and skin lesions, however, in one animal (with 19 days hospitalized), there was no complete regression of neurological alterations of bradycardia and muscle tremors, even so, it was possible to return to productive activity. High doses of pour on cypermethrin may cause systemic intoxication in cattle and result in bradycardia, hyperexcitability, muscle tremors and sialorrhea with irritant contact dermatitis, and death in severe cases.
Repercussões na saúde mental e infodemia de covid-19 de idosos paulistanos
Authors: Fhon Jack Roberto Silva , Püschel Vilanice Alves de Araújo , Cavalcante Ricardo Bezerra , Cruz Fabiana Viana , Gonçalves Luan Nogueira , Li Wilson , Silva Alice Regina Felipe
Published: August 2022

RESUMO Objetivo: Caracterizar e identificar sintomas depressivos, ansiedade e estresse associados à Infodemia de COVID-19 em idosos paulistanos. Método: Estudo exploratório e transversal com idosos da capital de São Paulo com acesso à internet. Foram analisados o perfil sociodemográfico, a infodemia de COVID-19, os sintomas depressivos, o estresse e a ansiedade. Resultados: Participaram 411 idosos. Predomínio do sexo feminino (76,4%), com ensino superior (57,9%), do uso de serviço de saúde privado e baixa variação na renda. Os idosos foram mais expostos a notícias ou informações sobre COVID-19 pela internet (45,3%), seguida pela televisão (34,5%) e pelo rádio (11,4%). A média de estresse foi 19,96 pontos; 33,1% apresentaram ansiedade e 39,7% sintomas depressivos. Quanto maior o número de pessoas que vivem com o idoso maior o estresse (p = 0,001) e a ansiedade (p = 0,02). As horas de exposição a informações pela internet levou a estresse (p = 0,001), sintomas depressivos (p = 0,02) e ansiedade (p = 0,02) do idoso. Conclusão Durante a pandemia, a exposição às informações pela internet desencadeou ansiedade, estresse e sintomas depressivos nos idosos. Os achados evidenciam a necessidade de intervenções multi e interdisciplinares para mitigar tais repercussões na saúde dos idosos.
A produção alimentar de base agroecológica e agroflorestal sob uma perspectiva marxista
Authors: Silva Luiz Felipe Barros
Published: August 2022

Resumo: O presente texto propõe iniciar um debate a partir da teoria social de Marx em torno das potencialidades e limites da agroecologia e da técnica agroflorestal, em especial aquela influenciada pelos princípios do suíço Ernst Götsch, que encontra grande ressonância no Brasil. É, também, uma tentativa de trazer para o Serviço Social debates externos, cujo matiz teórico-metodológico da profissão, crítico e de raiz marxiana, enseja sobre perspectivas tecnicistas da sociedade. A contradição entre relações técnicas e relações sociais é tratada aqui como um canal para dialogar sobre o quanto as relações técnicas estão subsumidas à forma social do capital. Intenta-se demonstrar que tal subsunção ocorre também com as técnicas agroecológicas e agroflorestais, funcionando como uma barreira a seu espraiamento e colocando em xeque o sistema social do capital, que não consegue atender à demanda social por alimentação saudável para todos.
Quilombola women and the struggle for territory from the perspective of decolonial feminism
Authors: Held Thaisa Maira Rodrigues , Campos Isadora Golim
Published: August 2022

Abstract The present work aims to analyze, from the point of view of decolonial feminism, the struggle of quilombola women for the recognition of their ancestral territories. Decolonial feminism manifests itself in the Latin American context, giving visibility to its subaltern representations, to Latin American, Afro-descendant, mestizo, and indigenous women, and in this scenario quilombola women are also included. In Brazil, decolonial theories and practices are drawn from theoretical discussions held by more classical theorists, such as Lélia Gonzalez and Sueli Carneiro, and contemporary ones, such as Carla Akotirene, to address issues that are closer to the reality of Brazilian women. The phenomena that support the theories are glimpsed in the daily struggles of black women, especially quilombolas, for the right to the recognition of their territories - denied by the State and which potentiates the various forms of violence, including gender violence. These practices are carried out by quilombola leaders in the private and public contexts and correspond to the notion of female empowerment linked to the collective context. For the analysis of the application of the theories and phenomena, the deductive method was used and as methodological procedures, the literature review and the analysis of available data and documents. We conclude that decolonial feminism should increasingly observe more the phenomena than the theories and that the feminine resistances in and through the quilombola territory go through struggles for the recognition of gender identities to mitigate the overlapping violence.
Política de Segurança Alimentar e Nutricional no enfrentamento da fome produzida pelos impérios alimentares
Authors: Nogueira Mariana Brito Horta , Pereira Simone Cardoso Lisboa , Carrara Virgínia Alves
Published: August 2022

Resumo Este artigo, de natureza qualitativa, recorre à metodologia bibliográfica e documental, consistindo em um ensaio apresentado em três seções, além da introdução e das considerações finais. Objetiva discutir a fome na agenda política brasileira que viola o direito ao acesso a alimentos de qualidade, em quantidade suficiente e sustentável. Problematiza sobre: a produção da fome como expressão da desigualdade de classe na sociedade capitalista; o direito à alimentação e a Política Nacional de Segurança Alimentar e Nutricional, a partir da análise socio-histórica do enfrentamento à fome e da formulação do arcabouço legal na agenda política brasileira; e como a estrutura e dinâmica do sistema alimentar hegemônico sustenta os impérios alimentares, com repercussão na redução do acesso à comida de verdade, no apagamento do patrimônio alimentar, desrespeitando a soberania alimentar, e no incentivo ao elevado consumo de alimentos/mercadorias ultraprocessados e seus efeitos deletério para a saúde humana e biodiversidade.
Assessment of the tolerance of soybean seeds to weathering deterioration in the pre-harvest phase by multivariate analysis
Authors: Pinheiro Daniel Teixeira , Dias Denise Cunha Fernandes dos Santos , Silva José Maria da , Gama Guilherme Fontes Valory , León Manuel Jesús Zavala , Silva Laércio Junio da
Published: August 2022

Abstract: Weathering deterioration in the pre-harvest phase impairs high-quality soybean seed production. The performance of several tests to infer seed quality is common in genotype selection, and multivariate statistics can assist in the interpretations. This study aimed to assess the efficiency of the principal component analysis (PCA) and canonical discriminant analysis (CDA) multivariate statistical methods in assessing the tolerance of seeds of different soybean cultivars to weathering deterioration in the pre-harvest phase under greenhouse conditions. Seeds of six soybean cultivars (DM 6563, BMX Apolo, BMX Potência, NA 5909, NS 5959, and TMG 1175) were produced. Different simulated precipitation levels (0, 60, 120, and 180 mm) were applied in the pre-harvest phase. The seeds were collected and assessed for physiological, physical, and biochemical analyses and the data were analyzed by PCA and CDA techniques. The results showed that PCA and CDA are efficient for assessing the tolerance to weathering deterioration in soybean seeds. PCA and CDA assisted in the recommendation of the tests first germination count, accelerated aging, tetrazolium, percentage of seeds with seed coat wrinkling, protein content, and protease activity in the pre-selection of genotypes for weathering deterioration. PCA and CDA also helped to identify the cultivars DM 6563 and BMX Potência as more susceptible and NA 5909 and TMG 1175 as more tolerant to weathering deterioration in the pre-harvest phase.
INSUCESSO ESCOLAR NUMA PERSPECTIVA DE GÉNERO – A PERCEÇÃO DOS ALUNOS
Authors: Cavaco Carmen , Paulos Catarina , Alves Natália , Guimarães Paula , Feliciano Paulo
Published: August 2022

RESUMO O texto problematiza o insucesso escolar numa perspectiva de género, a partir da perceção de alunos dos ensinos básico e secundário em Portugal. A análise resulta de uma investigação cujos dados empíricos foram recolhidos por meio de entrevistas semiestruturadas e de grupos focais. As estatísticas oficiais revelam uma taxa de insucesso escolar maior entre os rapazes, por comparação às raparigas. Todavia, os alunos não refletem, no seu quotidiano, sobre esse fenómeno e naturalizam-no com base em estereótipos de género. A construção de género ocorre em todos os tempos e espaços, incluindo a escola, porém, para os alunos envolvidos nesta pesquisa, o género é construído, sobretudo, no contexto familiar.
Alterações químicas e sanitárias em solos e estéril de mineração receptores de lodo de esgoto sanitário, composto orgânico e fertilizante mineral
Authors: Guimarães Roberta Nunes , Matos Antonio Teixeira de , Carpanez Thais Girardi
Published: August 2022

RESUMO Neste estudo, objetivou-se avaliar alterações químicas e sanitárias de solos e estéril de mina da região do Quadrilátero Ferrífero/MG, pela incorporação de lodo de esgoto sanitário e composto orgânico comercial, utilizando a adubação química convencional como tratamento controle. O estudo foi desenvolvido na área experimental da Mina de Águas Claras/MG, sendo os solos (Latossolo e Cambissolo) e estéril de mina analisados por um período de oito meses depois de efetuadas as adubações de, respectivamente, 49,9, 59,7 e 54,8 kg ha-1 de lodo de esgoto sanitário; 117,4, 140,1 e 128,8 kg ha-1 de composto orgânico comercial; e 150 kg ha-1 de fertilizante mineral em todos os materiais. No que se refere aos aspectos sanitários, o lodo de esgoto sanitário e o composto orgânico comercial foram classificados como “Classe A”, de acordo com a Resolução do Conselho Nacional do Meio Ambiente 375/2006. Após a aplicação dos adubos, avaliaram-se os teores de matéria orgânica, macro e micronutrientes, capacidade de troca catiônica, índice de saturação por bases, índice de saturação por alumínio, Al3+, H+Al, além dos teores de alguns metais pesados nos solos e estéril, além da quantificação de ovos viáveis de helmintos. Observou-se que a incorporação de lodo de esgoto sanitário e composto orgânico comercial foi capaz de aumentar os teores de matéria orgânica e fertilidade dos materiais e, embora a aplicação do lodo de esgoto sanitário também tenha proporcionado aumento nos teores de alguns metais pesados, não foi suficiente para proporcionar perda de sua qualidade ambiental, de acordo com a Conselho Nacional do Meio Ambiente 420/2009 (BRASIL, 2009). Não houve restrições sanitárias para o uso do lodo de esgoto sanitário em solos e estéril a serem recuperados em áreas de mineração do Quadrilátero Ferrífero/MG.
Contamination of groundwater by necro-leachate and the influence of the intervening factors in cemeteries of the municipality of Lages – Brazil
Authors: Baum Camila Angélica , Becegato Valter Antonio , Vilela Pâmela Becalli , Lavnitcki Laís , Becegato Vitor Rodolfo , Paulino Alexandre Tadeu
Published: August 2022

ABSTRACT Cemeteries are potential sources of groundwater contamination and, despite the several studies that evidence this sort of contamination, only a few consider how the aspects and characteristics of the unsaturated zone interfere in this process. This study evaluated the quality of groundwater in the areas of two cemeteries under the same precipitation regime, climate and burial practices, but with pedological differences. During one year, the physicochemical parameters potential hydrogen (pH), electrical conductivity, oxidation-reduction potential, dissolved oxygen, total dissolved solids, chemical oxygen demand, total phenols, total phosphorus and ammonia (NH3), as well as the heavy metals cadmium (Cd), lead (Pb), copper (Cu), chromium (Cr), nickel, (Ni) and zinc (Zn), were monitored in the groundwater from two cemeteries located in the urban area of the municipality of Lages, Brazil. Samplings were performed in monitoring wells inside the cemeteries and the local rainfall was registered. The quality of the groundwater from both cemeteries indicates contamination by necro-leachate constituents such as mineral salts, NH3, total phenols, Cd, Cr and Ni, which, besides being harmful to the environment, pose a risk to public health. The precipitation, which had a direct effect on the height of the water level in the groundwater aquifer, increased the levels of contaminants, while the reduced values of cation-exchange capacity (CEC), considering that a large part of the soil is occupied by Al3+ ions, reduced the adsorption potential of the other metals.
Environmental and economic evaluation of coffee residues
Authors: Freitas Lílian Carla Ferreira , Renó Maria Luiza Grillo
Published: August 2022

ABSTRACT Brazil is a country of agricultural culture, and for over a hundred years has been the largest coffee producer. Thus, the work proposes alternatives for the use of agricultural residues from coffee production, analyzing them from an environmental and economic point of view. A coffee crop was selected from the municipality of Santa Rosa da Serra (Minas Gerais, Brazil), and three scenarios were established. Scenario 1: husk is discarded outdoors; scenario 2: energy use of the husk for gasification and subsequent production of electricity; scenario 3: use of the husk as an organic fertilizer. An economic and environmental analysis was conducted from these three scenarios. The gasification technology with the coffee husk, although technically feasible, according to the economic analysis becomes unfeasible, since the value of this electric generation was higher than the other generation values. Scenarios 2 and 3 that applied sustainable practices resulted in negative values for the environmental impacts of water depletion and depletion of fossil fuels, proving the benefits of such practices. The gasification process needs technological development to make the enterprise economically viable. Sustainable practices in coffee cultivation bring environmental benefits in the short and long terms.
Comparação do processo de adsorção em batelada e em leito fixo do ácido naftênico 1,4-ciclohexanodicarboxílico em carvão ativado de osso de boi
Authors: Lopes Camila Narumi Yano , Silva Jonas Gabriel Domingues da , Lima Laressa Rayane Rosa , Caetano Gabriela Costa , Ostroski Indianara
Published: August 2022

RESUMO O ácido naftênico 1,4-ciclohexanodicarboxílico é um dos principais contaminantes do petróleo e das águas residuais de petroquímicas, podendo causar consideráveis danos às operações industriais bem como ao meio ambiente, devido ao seu caráter corrosivo e sua toxicidade. Uma operação que pode ser realizada para a separação deste contaminante é a adsorção. Nesse sentido, o presente trabalho teve como finalidade avaliar a capacidade e eficiência adsortivas do carvão ativado de osso de boi em sistemas em batelada e em leito fixo para a remoção do ácido 1,4-ciclohexanodicarboxílico. Inicialmente, os carvões ativados brutos e tratados com NaOH foram utilizados no sistema em batelada (pH = 3,2; m = 50 mg). Os valores dos dados cinéticos e os de equilíbrio indicaram o carvão tratado como um melhor adsorvente para o ácido naftênico, com quantidades retidas experimentais no equilíbrio de 380 mg.g−1. O carvão ativado tratado foi escolhido para os ensaios em leito fixo e, inicialmente, a vazão ótima de operação foi obtida. Os parâmetros de transferência de massa indicaram que os efeitos difusionais no leito foram minimizados em 2 mL.min− 1. A isoterma dinâmica foi obtida e avaliada como irreversível a partir dos balanços de massa nas curvas de ruptura, com altos valores de quantidades retidas (316,6 mg.g−1). Foram observados diferentes mecanismos de transferência de massa nos sistemas em batelada e contínuo. No entanto, os valores das capacidades de adsorção no equilíbrio foram semelhantes. Com isso, o carvão ativado de osso de boi foi favorável na remoção do ácido 1,4-ciclohexanodicarboxílico.
Testate amoebae (Amorphea, Amoebozoa, Cercozoa) as bioindicators: a scientometric review
Authors: Silva Yemna Gomes da , Sampaio Gabriela Silva , Ramos Beatriz Rodrigues D’Oliveira , Freitas Yasmin de Góes Cohn , Nascimento Letícia , Branco Christina Wyss Castelo , Miranda Viviane Bernardes dos Santos
Published: August 2022

Abstract: Aim The free-living protists testate amoebae are recognized as being bioindicators, able to reveal environmental alteration via remodifying richness, diversity and abundance of species. To assess the scientific production on the use of testate amoebae as bioindicators, a scientometric analysis was undertaken from 1960 to 2020. Methods The sourcing of scientific articles derived from Google Academic, Scielo, Science Direct and Online Library research platforms. All selected papers were factored according to chronology, journal of publication, country, authors’ affiliation, whether the study was empirical or experimentation, if it included solely testate amoebae or other groups of organisms, and aspects of the environment. Results A total of 215 papers from ninety-two journals revealed a notable increase in publication numbers over the last decades. The two journals that most published data on this theme were Microbial Ecology and Ecological Indicators. Whilst the largest number of papers was published in the European Continent, the countries that most contributed to the subject were Canada in the temperate region and Brazil in the tropics. Edward A.D. Mitchell published the largest number of studies and regarding institutions the Franche-Comté University. The majority of papers that associated testaceans as bioindicators were empirical, conducted with Thecamoebian inhabiting moss and as such, dissociated from other groups. Conclusions Despite a suggested uptick in research of testaceans as bioindicators, our results indicate a concentration of studies to limited regions of the globe. In another aspect, a great number of studies assess testaceans’ community as-a-whole, showing a shortage of in-depth knowledge into species and functional groups. Therefore, our survey points to a wide variety of aquatic ecosystems devoid of study matter, indicating the need to foster the research on testate amoeba's role as bioindicators especially in the tropical regions.
El pensamiento crítico en la economía política de la comunicación: Una propuesta no dogmática
Authors:   Universidad de Guadalajara, SÁNCHEZ RUIZ Enrique
Published: August 2022

La “crítica social” nos auxilia para evaluar lo positivo o lo negativo en la sociedad, tanto para individuos como para grupos, clases u otros agregados. Esta “crítica social” nos puede auxiliar para señalar problemas, conflictos o contradicciones sociales, para eventualmente proponer cambios, soluciones o salidas. En general, la utopía y la ideología son componentes prácticamente ineludibles de las ciencias sociales, en el punto de partida, aunque el rigor teórico y metodológico y una ética científica puedan ayudar a compensar la actitud valorativa que podría ostentar uno en un principio. En primer lugar, hay que dejar que sean preguntas, no certezas previas, las que guíen la investigación. Se necesita ejercer honestidad intelectual, autocrítica, autorreflexividad, vigilancia epistemológica. Son entonces dos los principales sentidos en los que se entiende la ciencia social crítica latinoamericana: por un lado, lo que hemos denominado “crítica social”, en la que partiendo de la historicidad del objeto de estudio y de enfoques enriquecidos con una aproximación histórica, a partir de la investigación empírica rigurosa se es capaz de mostrar los obstáculos y las contradicciones que impiden el desarrollo más pleno de los sujetos sociales y humanos. Por otro lado, en el sentido filosófico, original, de crítica como el conocimiento amplio y profundo de autores y textos, enriquecido a la vez con la acepción más moderna que toma en cuenta las condiciones históricas, materiales, de producción de tales textos.
El anciano en situación de dependencia y su familia : aportes desde una mirada interdisciplinaria
Authors: Martín Carbonell Marta de la Caridad ,   Universidad Cooperativa de Colombia, Fernández Daza Martha Patricia ,   Universidad Cooperativa de Colombia, Laguado Jaimes Elveny ,   Universidad Cooperativa de Colombia, Herrera Merchán Edna Johanna ,   Fundación para la intervención e investigación en comunidades vulnerables y sociales "estrellas en el cielo", Pereira Moreno Lady Johanna ,   Universidad Cooperativa de Colombia, Riquelme Marín Antonio ,   Universidad de Murcia, Llamazares Martín Blanca ,   Universidad de Murcia, Méndez Mateo María Inmaculada ,   Universidad de Murcia, Ortigosa Quiles Juan Manuel ,   Universidad de Murcia, Camargo Hernández Katherine del Consuelo ,   Universidad de Puerto Rico, Pérez Díaz Raquel ,   Ministerio de Salud Pública de Cuba
Published: August 2022

El envejecimiento exitoso es un tema en el que es posible encontrar abundante literatura, así como sobre los problemas de salud asociados con el envejecimiento, sin embargo, es más difícil encontrar textos actualizados sobre los aspectos psicosociales del cuidado de los ancianos enfermos, y en situación de dependencia. A través de una revisión crítica de la literatura, rastreando sus orígenes históricos y terminando con las contribuciones más actualizadas, se detallan los efectos cognitivos y físicos derivados del envejecimiento, el estrés de los cuidadores y las necesidades familiares de los pacientes geriátricos; institucionalización, problemas familiares, demencia. y cuidadores familiares. El libro gira en torno a tres ejes: el primero aborda los determinantes y las manifestaciones del envejecimiento que están asociadas a limitaciones de la autonomía y, por lo tanto, a la dependencia. Un segundo eje conceptual es la dependencia, funcionalidad y sus factores biopsicosociales determinantes. El último eje corresponde a los cuidadores familiares, el efecto de la sobrecarga y su calidad de vida. Este libro permite al lector obtener información clara y precisa sobre aspectos relacionados con el envejecimiento saludable, dependencia y responsabilidades en el cuidado de dichos pacientes, todo esto para generar una reflexión sobre la atención no solo del paciente geriátrico, sino de la familia, los programas en prevención y promoción en la salud en entidades públicas y privadas para cuidadores y familiares.
Conformational Analysis of Tyrosyl-Lysyl-Threonine Tripeptide Using MM, MD and QM Methods and Its Hyperpolarizability Study
Authors: BIÇAK Bilge , GUNDUZ Serda Kecel
Published: August 2022

Peptides are important structures that offer important opportunities for therapeutic interventions in various diseases. Tyrosyl-Lysyl-Threonine is an important peptide structure that contains the antiviral, antioxidant and anticancer properties of the amino acids in its structure. Examination of the conformational structure, which has great importance on both the ability of the molecule to fulfill its biological functions and electronic properties, is important for molecular studies. In this study, determination of the stable conformations and optimization of the most stable structure of Tyrosyl-Lysyl-Threonine molecule was carried out using molecular mechanical and quantum mechanical methods. With molecular dynamics simulation studies, the changes in conformational structure, RMSD and Rg values in different environments were monitored for 10 ns. Additionally, the hyperpolarizability study of Tyrosyl-Lysyl-Threonine were carried out. As a result of this study, it was aimed to determine the optimized geometry of the tripeptide, its conformational changes and nonlinear optical properties.
Temporal Analysis Based Driver Drowsiness Detection System Using Deep Learning Approaches
Authors: KUMRAL Furkan , KÜÇÜKMANİSA Ayhan
Published: August 2022

With the development of technology, artificial intelligence comes into our lives more and also comes up as a solution to many problems. Recently, deep learning approaches have been bringing fast and highly accurate solutions to problems. In this work, within the scope of Advanced Driver Assistance Systems (ADAS), deep learning based driver drowsiness detection system is proposed. First, face regions of drivers are detected using SSD MobileNet object detection method. The aim is to detect the eye, mouth and head positions of the drivers from this face region and to make a situation estimation with the combinations of these detected objects which are “normal”, “drowsy” and “danger”. The proposed approach examines the driver's behaviour over a certain period of time for making a decision, rather than a one-time eye closure or yawning decision. The detected eye, mouth and head positions are monitored and recorded over a period of time. Finally, these merged patterns are classified with Convolutional Neural Networks (CNN). Experimental results show that the performance of proposed novel CNN approach outperforms existing approaches in literature.
‘As Simple as Music’: Kinds of Noise in Sean Bonney’s Poetry
Authors: Allen Tom
Published: August 2022

This article considers Sean Bonney’s texts Happiness: Poems After Rimbaud (2011), Letters Against the Firmament (2015), Our Death (2019) and antimatter (2019). I write about each of these texts in terms of Bonney’s representation within them of music and noise. Rather than discussing this from a musicological perspective, or in relation to particular musical works, I address the metaphorical use that Bonney makes of figures of music and noise in general. I argue that in each case, the way in which Bonney conceives of music is indicative of a wider perspective on political and social reality and its capacity to be transformed by collective action. The article begins by elaborating the relationship between music and noise as I understand it to exist in Bonney’s writing. Following this, I elaborate the conditions of economic austerity under which Bonney lived during the writing of Happiness and Letters Against the Firmament. The article then aims to elaborate the relationship between a thinking of music and a thinking of community in Happiness before considering how harmony functions as a metaphor for class-domination in Bonney’s prose poetry. The article ends with a consideration of antimatter as a work whose use of rhyme and song-like structures is indicative of a specific ontology of catastrophe developed in Our Death.
Weight sensitivity and prominence in Laurentian French
Authors: Lamontagne Jeffrey , Goad Heather
Published: August 2022

Main prominence is conventionally described as being assigned to the final syllable of phrases in French, but previous quantitative and qualitative work has shown that this is not always the case. Using corpus data from Laurentian French (Saguenay, Quebec), we test the hypothesis that prominence is preferentially assigned to heavy syllables. Our results demonstrate that this is indeed the case, with both codas and heavy vowels attracting prominence away from final syllables, particularly when the final syllable is open. We infer two distinct types of prominence: lexical and phrasal. Lexical prominence, which is marked using duration and amplitude, variably attracts phrasal prominence, which is marked using pitch. We interpret these findings as indicating that the location of phrasal prominence is sensitive to syllable weight and that this prominence is best formally expressed as a pitch accent due to its attraction to lexically prominent syllables.
Substantive bias and the positional extension of major place contrasts
Authors: Glewwe Eleanor
Published: August 2022

The role of phonetic naturalness in biasing the learning of sound patterns remains an unsettled question in phonology. The present study investigates naturalness bias in phonotactic learning using a novel experimental paradigm that tests whether learners reproduce a phonetically-motivated phonotactic implicational about the distribution of major place contrasts in stops. Stops differing in place of articulation are easier to distinguish word-initially than word-finally, so place contrasts in word-final position should also exist in word-initial position. The reverse is not necessarily true. This implicational is typologically supported as well as motivated by perceptual naturalness. In two artificial grammar learning experiments, I exposed participants to place contrasts in stops either word-initially or word-finally and tested whether they extended the contrasts to the other word-edge position. Participants successfully learned to recognize novel words that fit the phonotactic pattern they had been trained on, but they were equally willing to extend the place contrasts in both directions, yielding no evidence for naturalness bias. These results contrast with those of a similar study that found asymmetric extension of the stop voicing contrast, supporting an effect of naturalness bias. Confusion data suggests that the reduction in perceptibility from word-initial to word-final position may be greater for stop voicing than for stop place of articulation. This difference may underlie the divergent results of the two studies, leading to the hypothesis that the strength of a substantive bias depends on the magnitude of its phonetic precursor.
Individual success, collective failure?
Authors: Durst Judit , Huszár Ákos
Published: August 2022

Public dialogue about social mobility in many countries has recently been dominated by the myth of meritocracy and uses a neo-liberal vocabulary of aspiration, ambition, and choice, considering mobility as an individual project of self-advancement involving moving up in the social hierarchy (Lawler & Payne, 2018; Friedman & Laurison, 2020). Meritocracy suggests that whatever your social position at birth, society ought to offer enough opportunity and mobility for ‘talent’, when combined with ‘effort’, to ‘rise to the top’. This idea is one of the most prevalent social and cultural tropes of our time (Littler, 2017). In this discourse, social mobility is the new panacea for wider historic and social ills, and the answer to the increase in classed and racialised inequalities. This special issue aims to challenge this widespread public and political discourse by deploying the sociological perspectives of social mobility and asking how (upward but also downward) mobility works, how fluid our contemporary societies are, what mobility means for those experiencing it, and what the social implications are of ‘individual […] success at the cost of collective failure’ (Reay, 2018). As an educational sociologist and academic with a working-class background, Diane Reay (2013) argues that ‘[a]t the collective level, social mobility is no solution to either educational inequalities or wider social and economic injustices. But at the individual level it is also an inadequate solution, particularly for those of us whose social mobility was driven by a desire to “put things right” and “make things better” for the communities we came from and the people we left behind.’ (Reay, 2013, p. 674). The papers in this issue are testimony to the theoretical stance that upward social mobility cannot be seen as an individual project but needs to be understood and analysed in the wider context of social inequalities (among others, Lawler & Payne, 2018; Friedman & Laurison, 2020; Bukodi & Goldthorpe, 2019). The authors tackle the topic of social mobility from two perspectives. The first group of the research papers measure and analyse social mobility processes using the conventional occupation and education indexes and the not-so-conventional ‘soft’ variables of the intergenerational transmission of parental capital(s) on mobility outcomes. Beyond these mainstream mobility studies, the second group of articles consists of ‘marginal research’ (Lawler & Payne, 2018), or small-scale investigations that provide readers with insights into how upwardly and downwardly mobile people experience mobility when they have to travel through social spaces, leaving behind one class and adjusting to life in another.
Racial glass ceiling
Authors: Durst Judit , Nyírő Zsanna , Dés Fanni , Boros Julianna
Published: August 2022

According to the neoliberal mantra, anyone who is willing to work hard can get ahead in our society. In an era when belief in the myth of meritocracy has become widespread, greater social mobility would represent the promise of escape from rising social inequality. This paper challenges this myth and offers insight into the fallacy of individualized explanations of the role of merit in social ascension. Drawing on 103 interviews with first-in-family (FIF) minority Roma graduates in Hungary, and using the lens of intersectionality, it explores the hidden barriers to career advancement for those Roma professionals whose parents do not have a degree. The paper shows how the intersections of class and racialised minority status matter in relation to what career one has in the labour market. It illuminates why FIF Roma professionals can rarely enter elite occupations and why, career wise, they tend to concentrate in jobs dealing with Roma issues. It explores the effect of the dynamic interaction of structural hidden mechanisms and the Roma’s response/adaptation to them that contribute both to Roma professionals’ labour market segmentation and to the phenomenon of the glass ceiling. The paper calls these two characteristics of the labour market situation of the FIF Roma graduates the racial glass ceiling.
Social selection step by step
Authors: Berényi Eszter
Published: August 2022

The article scrutinises the application process and its consequences in terms of educational inequalities in early selective grammar schools in Hungary. The focus is on the almost one-year-long process of preparation for the entrance exams to these grammar schools. Its main aim is to depict how the gradual nature of getting into secondary education intensifies social selection within the educational sector. The analysis is based upon the findings of a mixed method research, of which the results of the two waves of the survey and the consecutive interviews will be analysed. The article provides evidence of successful practices during the preparation process to these schools, as well as evidence of self-exclusion mechanisms for socially disadvantaged families. Overall, the results suggest that the most important selection factors are not the written or oral entrance exams themselves, but the decision to enter and remain in the preparation process, as well as the strategic decisions made by the parents during the preparation process.
Processing frozen human blood samples for population-scale Oxford Nanopore long-read DNA sequencing SOP v1
Authors: J Billingsley Kimberley
Published: August 2022

Abstract: As part of the GP2 initiative we will generate long-read sequencing data for ~1000 samples to better understand the genetic architecture of Parkinson's disease. To generate this large-scale Nanopore data we have developed a protocol for processing and long-read sequencing frozen human blood samples, targeting an N50 of ~30kb and ~30X coverage. Acknowledgements: We would like to thank the Nanopore team (Androo Markham &Hannah Lucio), Circulomics Inc team (Jeffrey Burke, Michelle Kim, Duncan Kilburn & Kelvin Liu) and the whole CARD long-read team listed below => UCSC: Benedict Paten, Mikhail Kolmogorov, Miten Jain, Kishwar Shafin, Trevor Pesout; NHGRI: Adam Phillippy, Arang Rhie; Baylor: Fritz Sedlazeck; JHU: Winston Timp; NINDS: Sonja Scholz; NIA: Cornelis Blauwendraat, Kimberley Billingsley, Frank Grenn, Pilar Alvarez Jerez, Bryan Traynor, Shannon Ballard, Caroline Pantazis; CZI: Paolo Carnevali. This protocol was optimized using frozen blood samples from the PPMI initiative. PPMI – a public-private partnership – is funded by the Michael J. Fox Foundation for Parkinson’s Research and funding partners, a full list of the PPMI funding partners can be found at www.ppmi-info.org/fundingpartners .
From Narrative Objects to Poetic Practices: On Figurative Modes of Urbanism
Authors: Hawkins Jeremy Allan
Published: August 2022

In the context of increased interest in literary methods for spatial design, this article argues for a reconsideration of narrative methods for urban planning. It holds that when narrative is taken not as a reified object but as an active mode, in which a strategy for organizing the phenomenal world allows for form to be created from and within the profusion of signs, the importance of heterogeneous non-narrative elements comes into full force, in particular around figurative or metaphorical language, even or especially within the narrative frame. Drawing on work from Bernardo Secchi and Paola Viganò on and around the “porous city” figure and the Greater Paris international consultations, the article makes a case for a narrative of poetic practices. By identifying the polysemic agency of the poetic function, the territorial figure becomes not a comparison between two terms, but a complex linking of similarities in multiple dissimilar states, creating an effect of rapprochement with new possible futures.
Investigation of Active Compounds in Propolis Structure Against Sars Cov-2 Main Protease by Molecular Docking Method: In Silico Study
Authors: ÖNER Erkan , DEMİRHAN İlter , YALIN Serap , BELGE KURUTAS Ergul
Published: August 2022

It was aimed to investigate the active ingredients limonin, quercetin and kaempferol in propolis against SARS-CoV-2 main protease(MPro) using in silico methods. Absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening of ligands assists US to state their absorption properties, toxicity, and drug-likeness. Ligand molecules obtained from PubChem in smiles format were loaded on SWISSADME and PROTOX-II webservers for ADMET screening. The three compounds in propolis were obtained from the PubChem database. Compounds were located at the active site of the SARS-CoV-2 MPro receptor with PDB ID:6LU7. Molecular docking work was done with Autodock program. Molecular docking results were found as -8.7 kcal/mol in limonin, -7.5 kcal/mol in quercetin and -7.7 kcal/mol in kaempferol. In silico ADMET estimation showed they have a potential for antiviral therapy. In conclusion, we thought that propolis active components limonin, quercetin and kaempferol have the potential to be a SARS CoV-2 MPro inhibitor.
Evaluation of ankle joint synovitis in diabetic neuroosteoarthropathy in relation to an inflammatory phase of chronic osteomyelitis
Authors:   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Stupina T.A. , Migalkin N.S. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Sudnitsyn A.S. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation, Mezentsev I.N. ,   Ilizarov National Medical Research Centre for Traumatology and Orthopedics, Kurgan, Russian Federation
Published: August 2022

Diabetic neuroosteoarthropathy complicated by osteomyelitis is one of the severe conditions of the ankle joint in patients with diabetes. The role of the synovium in the pathogenesis of this disease remains poorly understood. Purpose To identify structural changes in the synovium of the Charcot ankle depending on the inflammatory phase of chronic osteomyelitis. Material and methods The synovium and osteochondral fragments of the ankle were studied in 33 patients. Paraffin sections stained according to the three-color Masson method, hematoxylin and eosin, and semi-thin sections stained with methylene blue and basic fuchsin were studied using an AxioScope. A1 microscope with an AxioCam digital camera (Carl Zeiss MicroImaging GmbH, Germany) and Zenblue software (Carl Zeiss MicroImaging GmbH, Germany). The phase of the inflammatory process of chronic osteomyelitis was assessed according to the HOES of Tiemann et al (2014) and synovitis according to Krenn et al (2006). Results Full-thickness articular cartilage defects, synovial pannus, foci of osteonecrosis in the subchondral zone, bone microsequesters, osteoclastic resorption of the subchondral bone plate, replacement of bone marrow structures with granulation tissue, the severity which depended on the inflammatory stage of chronic osteomyelitis, were recorded in the process of studying osteochondral fragments. In 82 % of patients, the inflammatory phase of chronic osteomyelitis was characterized as active and subacute. In all the cases, hyperplasia, hypervascularization and hyperemia of the synovium with the presence of bone and cartilage fragments were observed, as well as inflammatory infiltrate, synovial pannus invading the articular cartilage. The vessels featured a pronounced narrowing of the lumens or their complete closure. The severity of synovitis correlated positively with the inflammatory phase of chronic osteomyelitis; Spearman's correlation coefficient of 0.76 indicated high relationship. Conclusions In diabetic osteoarthropathy of the ankle joint complicated by chronic osteomyelitis, the irreversible structural changes revealed in the synovium contribute to the formation of synovial pannus and the progression of destruction of the articular cartilage and subchondral bone. The severity of synovitis positively correlates with the inflammatory phase of chronic osteomyelitis.
Pyomyositis: case series of 14 patients to study the significance of early diagnosis and management
Authors:   Guru Gobind Singh Medical College and Hospital, Faridkot, India, Gupta P. , Garg Sh. ,   Guru Gobind Singh Medical College and Hospital, Faridkot, India, Garg K. ,   Kalpana Chawla Government Medical College, Karnal, India, Jindal M. ,   Kalpana Chawla Government Medical College, Karnal, India, Gupta V. ,   Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, India, Garg A. ,   Kalpana Chawla Government Medical College, Karnal, India
Published: August 2022

Introduction Pyomyositis denotes primary pyogenic infection of skeletal muscle. It is predominantly a disease of tropical countries. It usually involves the largest muscle groups around the pelvic girdle and lower extremities. Primary reasons for delay in diagnosis are its low incidence and vague presentation [7]. This delay can result in complications such as extension into and destruction of an adjacent joint, sepsis and, even death. Our study is aimed to highlight the extent and sequence of treatment protocol required for good management of these patients. Methods We retrospectively analyzed our experience with a series of 14 pediatric patients with primary pyomyositis who were treated and followed up. There were five girls and nine boys. All 14 patients underwent plain radiographs, USG and MRI of the affected area followed by surgical drainage and a course of antibiotics. Patients were followed up with weekly CRP. Results Six out of 14 (42.9 %) patients had a history of mild trauma. Ileopsoas muscle was involved in 4 patients, 3 cases in which the gluteals or quadriceps were involved, 2 cases with obturator muscle involvement and 2 cases in which adductors were the infection site. All 14 patients were treated surgically. Conclusion Our study shows that early diagnosis, complete drainage of the purulent material and the use of appropriate antibiotic therapy are the key determinants of successful treatment that lead to complete resolution in the majority of cases.
Reconstruction of soft tissue defects using transposition loco-regional perforator island flaps
Authors:   Stavropol Regional Clinical Hospital, Stavropol, Russian Federation, Vorotnikov A.A. ,   Stavropol State Medical University, Stavropol, Russian Federation, Rumyantsev D.O. ,   Stavropol Regional Clinical Hospital, Stavropol, Russian Federation, Airapetov G.A. ,   Stavropol Regional Clinical Hospital, Stavropol, Russian Federation,   Stavropol State Medical University, Stavropol, Russian Federation, Dushin R.V. ,   Stavropol Regional Clinical Hospital, Stavropol, Russian Federation, Shindin A.N. ,   Stavropol Regional Clinical Hospital, Stavropol, Russian Federation
Published: August 2022

Introduction Treatment of chronic non-healing wounds in the presence of deep post-traumatic soft tissue defects is a challenge for trauma reconstruction. The objective of the study was to improve healthcare quality for patients with chronic soft tissue defects of the limb. The goals included evaluation of the effectiveness of reconstruction of defects of the lower limb using local transposition perforant flaps, and rationale for a preferred choice for the keystone perforator flap. Material and methods The review included 48 patients with post-traumatic and osteomyelitic soft tissue defects of lower limbs. Patients were divided into 2 groups. Patients of the study group were treated with regional perforator fasciocutaneous flaps combined with osteonecrectomy that could be also performed later (n = 22). In the comparison group (n = 26), post-traumatic and osteomyelitic defects were treated with conventional methods of local wound treatment, staged osteonecrectomies followed by autodermoplasty. Results The use of the transposition loco-regional perforator flaps resulted in the incidence of secondary necrosis reduced by 33.7% and the two-fold reduction in the average number of staged operations. One-stage reconstruction was performed in 72.7 % patients of the study group. The length of inpatient treatment decreased by an average of 30 bed days. Discussion The reduced length of treatment in the study group could be caused by the absence or a significantly reduced stage of local wound treatment; there were fewer complications in the form of secondary necrosis of deep-lying tissues that would require additional treatment stages. Conclusions Reconstruction of osteomyelitic defects with the transposition of loco-regional perforant flaps allowed lower complication rate and improved functional outcomes for patients with posttraumatic and osteomyelitic defects of soft tissues of lower limbs.