bluuebunny/crossref_metadata_2025 huggingface dataset:
Es posible eliminar la corrupción?
Authors: Camacho García Julián Alberto
Published: July 2019

Se ha dicho de la corrupción que es el mayor obstáculo al crecimientoeconómico y social de los países en el mundo, no obstante, no se habla queprecisamente es ese afán de progreso económico el que da origen a lasconductas jurídicas y antijurídicas, que lesionan un patrimonio colectivo creadoen torno al desarrollo del ser humano. Este artículo busca plantear que esmás importante orientar la lucha contra las causas de la corrupción quecontra la corrupción misma, lo cual se generará con la modificación de losprincipios que orientan el sistema económico actual, con el ejercicio de unademocracia real, representativa, basada en la defensa del ser humano, y conla consolidación de una estructura normativa que permita la creación de unasociedad justa en función del bien común, recuperando la dimensión delsujeto, repensando las condiciones de existencia propias y de la comunidad,para no desbordar el equilibrio entre el ser humano y la naturaleza.
Las fuerzas militares y de policía en el postconflicto colombiano
Authors: Martínez Becerra Carlos Julio
Published: July 2019

El artículo plantea una hipótesis respecto al papel de la fuerza pública en elposconflicto, pues en lugar de dedicarse a la guerra debería implementarpolíticas públicas para que se articule en torno a tareas de paz, como laconstrucción de infraestructura donde los ingenieros militares podrían jugarun buen papel. La inversión para la guerra –que es un gasto estéril- deberáreorientarse hacia la paz por medio de estrategias de presencia con obras delEstado en todo el territorio nacional. El tema cobra mayor vigencia conocasión de la liberación del general Alzate y la reanudación de los Diálogosde La Habana, al mirar la pobreza extrema en que se encuentra el Chocó.
Paz en Colombia
Authors: Calvo Buezas Tomás
Published: July 2019

La exigencia hecha por el país colombiano de que se haga efectiva la firmade los acuerdos de paz entre el Gobierno y las FARC, la guerrilla más antiguade latinoamericana, despierta en el autor de este artículo, la necesidad dehacer la invitación para que entre todos construyamos la paz que este paístanto anhela. A manera de relato el autor nos cuenta los tiempos en que deuna u otra forma hubo comprensión con la guerrilla, habla además de lagente que conoció, que despertó en él la admiración y la necesidad de lucharpor una sociedad justa, habla del cura Camilo Torres, de Domingo Laín,José Antonio Jiménez y Manuel Pérez. Es pues, objeto principal de este autorreflexionar sobre el ideal de revolución de la guerrilla. “Vuestros ideales dejusticia fueron nobles, pero el medio de la violencia armada fue nefasto ycriminal”.
Comparison of factor retention methods on binary data: A simulation study
Authors: KILIÇ Abdullah Faruk , UYSAL İbrahim
Published: July 2019

﻿In this study, the purpose is to compare factor retention methods under simulation conditions. For this purpose, simulations conditions with a number of factors (1, 2 [simple]), sample sizes (250, 1.000, and 3.000), number of items (20, 30), average factor loading (0.50, 0.70), and correlation matrix (Pearson Product Moment [PPM] and Tetrachoric) were investigated. For each condition, 1.000 replications were conducted. Under the scope of this research, performances of the Parallel Analysis, Minimum Average Partial, DETECT, Optimal Coordinate, and Acceleration Factor methods were compared by means of the percentage of correct estimates, and mean difference values. The results of this study indicated that MAP analysis, as applied to both tetrachoric and PPM correlation matrices, demonstrated the best performance. PA showed a good performance with the PPM correlation matrix, however, in smaller samples, the performance of the tetrachoric correlation matrix decreased. The Acceleration Factor method proposed one factor for all simulation conditions. For unidimensional constructs, the  DETECT method was affected by both the sample size and average factor loading.
"Mão na Roda": uma roda de choro didática
Authors: Pereira Marcus Vinícius Medeiros
Published: July 2019

O texto analisa uma proposta de roda de choro didática no âmbito do Projeto Mão na Roda. O Projeto ocorre na cidade de Juiz de Fora/MG e tem o objetivo de fomentar o interesse pelo choro, bem como aproximar músicos com diferentes níveis de experiência desta linguagem. O estudo caracterizou-se como uma microanálise etnográfica, envolvendo a observação participante, entrevistas semiestruturadas e coleta de dados em páginas oficiais do projeto no Facebook. Os resultados apontam para uma transposição didática não dos conhecimentos musicais envolvidos na prática, mas uma transformação do contexto de prática em um laboratório que potencializa a aprendizagem musical. Observou-se que a roda didática se estrutura em cinco momentos: escolha da música que será executada; comentários prévios sobre a música escolhida; performance; comentários sobre a execução e repetição da performance da mesma música. Estes momentos são permeados por gestos didáticos do orientador da roda: gestos de presentificação, materialização, formulação de tarefas, elementarização e regulação. A roda didática, como um todo, pode ser entendida como um grande gesto didático de institucionalização que busca apresentar uma situação-problema real que permita aos envolvidos identificar, desenvolver e mobilizar os conhecimentos necessários. O processo de aprendizado que ocorre naturalmente em rodas tradicionais é potencializado pela ação de um orientador e precisa ser complementado por uma ação individual de cada músico para além do momento da roda. O estudo contribui para o debate em torno da formação de músicos, de professores de música e para o processo de didatização de outros gêneros e estilos musicais.
Parametric Vibrations of Axially Moving Beams with Multiple Edge Cracks
Authors: Sarıgül Murat
Published: July 2019

Nonlinear transverse vibrations of axially moving beams with multiple cracks is handled studied. Assuming that the beam moves with mean velocity having harmonically variation, influence of the edge crack on the moving continua are investigated in this study. Due to existence of the crack in the transverse direction, the healthily beam is divided into parts. The translational and rotational springs are replaced between these parts so that high stressed regions around the crack tips are redefined with the springs' energies. Thus, the problem is converted to an axially moving spring-beam system. The equations of motion and its corresponding conditions are obtained by means of the Hamilton Principle. In numerical analysis, the natural frequencies and responses of the spring-beam system are investigated for principal parametric resonance in detail. Some important results are obtained; the natural frequencies decreases with increasing crack depth. In case of the beam travelling with high velocities, the effects of crack's depth on natural frequencies seems to be vanished.
Suppression of Vibrations Induced by Fluctuating
Wind for Long-Span Cable-Stayed Bridge Using
MR Dampers
Authors: Xu Zhao-Dong , Xu Meng , Jia Da-Huan
Published: July 2019

Cable-stayed bridges subjected to wind excitations will cause intense vibration due to their high flexibility in
characteristic. Employment of magnetorheological (MR) dampers to realize the vibration smart-control of cablestayed bridges has become a considerable research topic in recent decades. In this paper, the plane truss finite
element model (FEM) of a cable-stayed bridge with MR dampers is established. Fluctuating wind field is generated
using the weighted amplitude wave superposition (WAWS) method and Kaimal spectrum, and then the time-history
sample curve of wind speed is obtained. Fluctuating wind-induced vibration of the long-span cable-stayed bridge
installed with MR dampers is analyzed by linear quadratic regulator (LQR) classical optimal control strategy and
LQR tri-state control strategy. After the optimal control force is calculated by LQR classical optimal control
strategy, control parameters and the input currents of MR dampers can be determined according to the windinduced vibration by LQR tri-state control. Results show that longitudinal and vertical wind-induced vibration
responses of the box girder of the cable-stayed bridge are reduced obviously when MR dampers are arranged
between the box girder and pylons.
Application of Variational Mode Decomposition and Permutation Entropy for Rolling Bearing Fault Diagnosis
Authors: Zheng Xiaoxia , Zhou Guowang , Li Dongdong , Ren Haohan
Published: July 2019

Rolling bearings are the key components of rotating machinery. However, the incipient fault characteristics of
a rolling bearing vibration signal are weak and difficult to extract. To solve this problem, this paper presents
a novel rolling bearing vibration signal fault feature extraction and fault pattern recognition method based on
variational mode decomposition (VMD), permutation entropy (PE) and support vector machines (SVM). In the
proposed method, the bearing vibration signal is decomposed by VMD, and the intrinsic mode functions (IMFs)
are obtained in different scales. Then, the PE values of each IMF are calculated to uncover the multi-scale intrinsic
characteristics of the vibration signal. Finally, PE values of IMFs are fed into SVM to automatically accomplish
the bearing condition identifications. The proposed method is evaluated by rolling bearing vibration signals. The
results indicate that the proposed method is superior and can diagnose rolling bearing faults accurately.
Lamb Waves Topological Imaging of Multiple Blind Defects in an Isotropic Plate
Authors: Zhu Wen-Fa , Zhang Hai-Yan Zhang , Xu Meng-Yun , Fan Guo-Peng
Published: July 2019

The study investigates the feasibility of the Lamb wave topological imaging method for detecting multiple blindholes in an isotropic plate. The topological imaging method is performed based on the computations of two
wave fields, a forward and an adjoint, in the defect-free reference medium using different emitting sources. The
image is computed by multiplying the forward and adjoint wave fields together and integrating them over time or
frequency. The interferences of multimode aliasing and the scattering effect can thus be eliminated at the defectfree positions with an improved image resolution. To investigate the physical mechanism, the refocusing process of
the multimode Lamb waves at the defect positions is presented by a face-to-face comparison between the snapshots
of the forward and adjoint wave fields using the finite element simulation. The Lamb wave topological imaging
method is numerically and experimentally verified to identify multiple blind-holes in an isotropic aluminium plate.
The results demonstrate that the topological imaging method enables the suppression of the sartefacts resulting
from the mode conversion and achieve high-resolution imaging of the blind defects
Vibration Characteristic of a Transition Constrained Damping Beam Based on the Shear Dissipating Energy Assumption
Authors: Yan Bijuan , Liang Huijun , Jin Minjie
Published: July 2019

Adding a “transition layer” could further improve the dissipation ability of the original constrained damping structure to the external vibration. At the same time, the addition of the transition layer brings many difficulties in
establishing the model and acquiring the relevant characteristics of the• structure. Based on the shear dissipating
energy assumption and the Hamilton principle, the finite element model of the transition constrained damping
beam is established. On the basis of this reasonable assumption, the whole derivation process is simplified and
easy to read by regularizing the element stiffness and mass matrix, and the expression of loss factor and natural
frequency of damping beam is obtained. In order to verify the correctness of the model, the computed results are
compared with the analytical solution, and both are found to be in good agreement. Taking the cantilever damping
beam as an example, the influence of the material choice of the transition layer and the structural parameters on
the natural frequency and the loss factor of the structure are discussed. The results of this paper would lay a good
foundation for further optimization and practical engineering application.
Do Sound Segments Contribute to Sounding Charismatic? Evidence from a Case Study of Steve Jobs' and Mark Zuckerberg's Vowel Spaces
Authors: Niebuhr Oliver , Gonzalez Simon
Published: July 2019

The paper presents a case study of two popular US American CEOs. It compares the acoustic vowel space sizes
of the more charismatic speaker Steve Jobs and those of the less charismatic speaker Mark Zuckerberg, as part of
an initial acoustic step to examine a traditional claim of rhetoric that clearer speech makes a speaker sound more
charismatic. Analysing about 2,000 long and short vowel tokens from representative keynote speech excerpts of the
two speakers shows that Jobs’ vowel space is, across various segmental and prosodic context factors, significantly
larger than that of Zuckerberg, whose vowel space is strongly reduced particularly when addressing investors.
The differences in vowel-space size are consistent with the claim of rhetoric that a clear articulation is a key
characteristic of a charismatic speaker. The discussion of the results describes further experimental steps required
to back up the link between clear pronunciation and speaker charisma.
Comparative Study of The Reactivity of the Tungsten Oxides WO2 And WO3 With Beryllium at Temperatures up to 1273 K
Authors: Köppen Martin
Published: July 2019

Tungsten oxides play a pivotal role in a variety of modern devices e.g. switchable glasses, wastewater treatment and modern gas sensors and metallic tungsten is used as armour material for e.g. gas turbines and future fusion power devices. In the first case you want to keep the oxide as functional material, while in the second case oxides can lead to catastrophic failures and you want avoid oxidation of tungsten. In both cases it is crucial to understand the stability of the tungsten oxides against chemicals. In this study the different reactivity of tungsten oxides towards the highly oxophilic beryllium is studied and compared. Tungsten--(IV)--oxide and tungsten--(VI)--oxide layers are prepared on a tungsten substrate. In the next step a thin film of beryllium is evaporated on the samples. In consecutive steps the sample is heated in steps of 100 K from r.t. to 1273 K. The chemical composition is investigated after each experimental step by high resolution X-ray photoelectron spectroscopy (XPS) of all involved core levels as well as the valence bands. A model is developed to analyse the chemical reactions after each step. In this study, we found the tungsten trioxid is reduced already by beryllium at r.t. and starts to react towards the ternary compounds BeWO_3 and BeWO_4 at temperatures starting from 673 K. However, the tungsten dioxide sample is reduction resistant to tempartures up to 1173 K. In conclusion, we found the WO_2 surface to be much more chemical resistant towards the reduction agent Be than WO_3.
Plasma Spectroscopy of Various Types of Gypsum: An ideal Terrestrial Analogue
Authors: Rai Abhishek K. , Pati Jayanta K. , Parigger Christian G. , Rai Awadhesh K.
Published: July 2019

The first detection of gypsum (CaSO4.2H2O) by the Mars Science Laboratory (MSL) rover Curiosity in the Gale Crater, Mars created a profound impact on planetary science and exploration. The unique capability of plasma spectroscopy involving in situ elemental analysis in extraterrestrial environments, suggesting the presence of water in the red planet based on phase characterization and providing a clue to Martian paleoclimate. The key to gypsum as an ideal paleoclimate proxy lies in its textural variants, and in this study terrestrial gypsum samples from varied locations and textural types have been analyzed by Laser Induced Breakdown Spectroscopy (LIBS) technique. Petrographic, sub-microscopic and powder X-ray diffraction characterizations confirm the presence of gypsum (hydrated calcium sulphate; CaSO4.2H2O), bassanite (semi-hydrated calcium sulphate; CaSO4.1/2H2O) and anhydrite (anhydrous calcium sulphate; CaSO4) along with accessory phases (quartz and jarosite). The principal component analysis of LIBS spectra from texturally varied gypsums can be differentiated from one another because of the chemical variability in their elemental concentrations. The concentration of gypsum is determined from the partial least-square regressions model. Rapid characterization of gypsum samples with LIBS is expected to work well in extraterrestrial environments.
“Doing my profession is also part of worship”: How Clinical Psychologists Address Aspects of Spirituality and Religion in Indonesia
Authors: Liem Andrian
Published: July 2019

This study aimed to explore how Indonesian clinical psychologists (CPs) address aspects of spirituality and religion (SR), particularly their attitudes towards and experience of it, on the mental health context. Semi-structured interviews were conducted with 43 CPs in public health centres in Yogyakarta Province, Indonesia. Data were anyalsed using deductive thematic analysis and they generated ten sub-themes which were merged into three central themes. The first theme was experiences related to SR, particularly in Indonesian sociocultural context. The second theme concentrated on participants’ clinical experience related to SR integration into clinical practice. The last theme highlighted the effort made by participants to create holistic mental health services. The originality of this study was represented by the interview quote in the title, “Doing my profession is also part of worship”. It was found that SR is part of culture and belief among Indonesian people, including CPs and mental health treatment clients. In summary, participants genuinely acknowledged that they were not able to completely detach SR from their professional practice. However, participants also pointed out that they were different with spiritual-religious healers (SRHs) and favourably welcomed future collaboration with credible SRHs. This positive attitude embodied a holistic care approach that recognises the diverse biopsycho-social-spiritual needs of clients. Therefore, professional organisations and psychology faculties should establish regulations and education of SR in psychology curricula and conventional psychotherapy to achieve this holistic mental health services in Indonesia.
Fetal Heart Rate Signal Dataset for Training Morphological Analysis Methods and Evaluating them Against an Expert Consensus
Authors: Boudet Samuel , Houze de l'Aulnoit Agathe , Demailly Romain , Delgranche Aline , Peyrodie Laurent , Beuscart Régis , Houzé de l'Aulnoit Denis
Published: July 2019

The fetal heart rate (FHR) is a screening signal for preventing fetal hypoxia during labor. When experts analyze this signal, they have to position a baseline and identify decelerations and accelerations. These steps can potentially be automated and made more objective by data processing analysis, but training and evaluation datasets are required. Here, we describe a dataset of 155 FHR recordings in which a reference baseline, accelerations and decelerations have been annotated by expert consensus. 66 FHR recordings with a shared expert analysis have been included in a training dataset, and 90 other FHR recordings with a non-shared expert analysis have been included in an evaluation dataset. Researchers wishing to evaluate their automatic analysis method should submit their results for comparison with the expert consensus. The dataset also contains the results produced by 11 re-coded automatic analysis methods from the literature. All the data are available at http://utsb.univ-catholille.fr/fhr-review.
English Language Proficiency and Immigrant Families Annual Earnings and Medical Care Spending in the USA
Authors: Niankara Ibrahim
Published: July 2019

This paper investigates the role of English language proficiency (ELP) as a measure of cultural integration on U.S. immigrant families’ economic integration, as measured by annual earnings, and health care market integration, as captured by annual medical care spending. Bayesian Markov Chain Monte Carlo (MCMC) estimation of a mixed bivariate ordered probit (MBOP) model of annual earnings and medical care spending is conducted using a nationally representative pooled cross-sectional sample data from the U.S. National Health Interview Surveys (NHIS). The results reveal that limited English proficiency is associated with lower marginal earnings propensities (-$44.83, -$50.66, and -$56.97), and higher marginal medical care spending propensities ($8.09, $6.09, and $4.32) for each of the three decreasing levels of ELP. Furthermore, we find a small yet statistically significant positive 7.2% correlation between immigrant families’ annual earnings and medical care spending propensities. Therefore investing to raise immigrants’ families ELP in the U.S. would not only contribute to more effective socio-economic integration, but also strengthen the U.S. workforce and economy for decades to come.
Ubiquitous Carbohydrate Binding Modules Decorate 936 Lactococcal Siphophage Virions
Authors: Hayes Stephen , Mahony Jennifer , Vincentelli Renaud , Ramond Laurie , Nauta Arjen , Sinderen Douwe , CAMBILLAU Christian
Published: July 2019

Abstract: With the availability of an increasing number of 3D structures of bacteriophage components, combined with powerful in silico predictive tools, it has become possible to decipher the structural assembly and functionality of phage adhesion devices. In the current study, we examined 113 members of the 936 group of lactococcal siphophages, and identified a number of Carbohydrate Binding Modules (CBMs) in the neck passage structure and major tail protein, on top of evolved Dit proteins as recently reported by us. The binding ability of such CBM-containing proteins was assessed through the construction of green fluorescent protein fusion proteins and subsequent binding assays. Two CBMs, one from the phage tail and another from the neck, demonstrated definite binding to their phage-specific host. Bioinformatic analysis of the structural proteins of 936 phages reveals that they incorporate binding modules which exhibit structural homology to those found in other lactococcal phage groups and beyond, indicating that phages utilize common structural “bricks” to enhance host binding capabilities. The omnipresence of CBMs in Siphophages supports their beneficial role in the infection process, as they can be combined in various ways to form appendages with different shapes and functionalities, ensuring their success in host detection in their respective ecological niches.
Analysis of Shear Failure of Surface Methane Capture Boreholes for Improving Efficient Drainage Period–A Lithology Perspective
Authors: Xu Hongjie , Fang Zezhong , Sang Shuxun , Yang Jingfen , Liu Huihu , Ding Hai , Dou Xinzhao
Published: July 2019

The shear failure of surface methane capture borehole (SMCB) is the main cause of shortening life cycle of SMCB but lack of lithological analysis. In order to improve the stability of SMCB and improve efficient drainage period, it is of great significance to investigate the lithology performances for shear failure of SMCB. Based on the direct shear tests and geological method, the results shows that the shear displacement increases as the grain size decreases. Mechanical jump occurs at the lithological boundaries, which is mainly determined by the composition of rock specimens. The cohesion is the mainly possible reason for the step change of shear strength. Lithology with high quartz and low clay may effectively improve shear strength and failure resistance. Boreholes drilled into the weaker siltstone and mudstone sections may potentially experience preferential damage due to the larger shear displacement and shear strength. Protective measures at these sections may improve the stability of the borehole casing. The probing data where it was found that boreholes closure validated the prediction.
Tumor Transcriptome in Patients with Lower Pectoralis Muscle Area Reveals IL-8 as a Prognostic Biomarker in Non-Small Cell Lung Cancer
Authors: Santiloni Cury Sarah , de Moraes Diogo , Paccielli Freire Paula , de Oliveira Grasieli , Venâncio Pereira Marques Douglas , Javier Fernandez Geysson , Dal-Pai-Silva Maeli , Nishida Hasimoto Érica , Pintor dos Reis Patricia , Regina Rogatto Silvia , Francisco Carvalho Robson
Published: July 2019

Cachexia is a syndrome characterized by an ongoing loss of skeletal muscle mass associated with poor patient prognosis in non-small cell lung cancer (NSCLC). However, prognostic cachexia biomarkers in NSCLC are unknown. Here, we analyzed computed tomography (CT) images and tumor transcriptome data to identify potentially secreted cachexia biomarkers (PSCB) in NSCLC patients with low-muscularity. We integrated radiomics features (pectoralis muscle, sternum, and T10 vertebra) from CT of 89 NSCLC patients, which allowed us to identify an index for screening muscularity. Next, a tumor transcriptomic-based secretome analysis from these patients (discovery set) was evaluated to identify potential cachexia biomarkers in patients with low-muscularity. The prognostic value of these biomarkers for predicting recurrence and survival outcome was confirmed using expression data from eight lung cancer datasets (validation set). Finally, C2C12 myoblasts differentiated into myotubes were used to evaluate the ability of the selected biomarker, IL-8, in inducing muscle cell atrophy. We identified 75 over-expressed transcripts in patients with low-muscularity, which included IL6, CSF3, and IL8. Also, we identified NCAM1, CNTN1, SCG2, CADM1, IL8, NPTX1, and APOD as PSCB in the tumor secretome. These PSCB were capable of distinguishing worse and better prognosis (recurrence and survival) in NSCLC patients. IL8 was confirmed as a predictor of worse prognosis in all validation sets. In vitro assays revealed that IL-8 promoted C2C12 myotube atrophy. Tumors from low-muscularity patients presented a set of upregulated genes encoding for secreted proteins, including pro-inflammatory cytokines that predict worse overall survival in NSCLC. Among these up-regulated genes, IL8 expression in NSCLC tissues was associated with worse prognosis and the recombinant IL-8 was capable of triggering atrophy in C2C12 myotubes.
Assessment of Drugs Toxicity and Associated Biomarker Genes Using Hierarchical Clustering
Authors: Hasan Mohammad Nazmol , Malek Masuma Binte , Begum Anjuman Ara , Rahman Moizur , Mollah Md. Nurul Haque
Published: July 2019

Assessment of drugs toxicity and associated biomarker genes is one of the most important tasks in the pre-clinical phase of drug development pipeline as well as in the toxicogenomic studies. There are few statistical methods for the assessment of doses of drugs (DDs) toxicity and their associated biomarker genes. However, these methods consume more time for computation of the model parameters using the EM (Expectation-Maximization) based iterative approaches. To overcome this problem, in this paper, an attempt is made to propose an alternative approach based on hierarchical clustering (HC) for the same purpose. There are several types of HC approaches whose performance depends on different similarity/distance measures. Therefore, we explored suitable combinations of distance measures and HC methods based on Japanese Toxicogenomics Project (TGP) datasets for better clustering/co-clustering between DDs and genes as well as to detect toxic DDs and their associated biomarker genes. We observed that Word’s HC method with each of Euclidean, Manhattan and Minkowski distance measures produces better clustering/co-clustering results. For an example, in case of glutathione metabolism pathway (GMP) dataset LOC100359539/Rrm2, Gpx6, RGD1562107, Gstm4, Gstm3, G6pd, Gsta5, Gclc, Mgst2, Gsr, Gpx2, Gclm, Gstp1, LOC100912604/Srm, Gstm4, Odc1, Gsr, Gss are the biomarker genes and Acetaminophen_Middle, Acetaminophen_High, Methapyrilene_High, Nitrofurazone_High, Nitrofurazone_Middle, Isoniazid_Middle, Isoniazid_High are their regulatory (associated) DDs explored by our proposed co-clustering algorithm based on the distance and HC method combination Euclidean: Word. Similarly, for the PPAR signaling pathway (PPAR-SP) dataset Cpt1a, Cyp8b1, Cyp4a3, Ehhadh, Plin5, Plin2, Fabp3, Me1, Fabp5, LOC100910385, Cpt2, Acaa1a, Cyp4a1, LOC100365047, Cpt1a, LOC100365047, Angptl4, Aqp7, Cpt1c, Cpt1b, Me1 are the biomarker genes and Aspirin_Low, Aspirin_Middle, Aspirin_High, Benzbromarone_Middle, Benzbromarone_High, Clofibrate_Middle, Clofibrate_High, WY14643_Low, WY14643_High, WY14643_Middle, Gemfibrozil_Middle, Gemfibrozil_High are their regulatory DDs. These results are validated by the available literature and functional annotation.
Accurate, Detailed, and Automatic Modelling of Laser-Scanned Trees
Authors: Du Shenglan , Lindenbergh Roderik , Ledoux Hugo , Stoter Jantien , Nan Liangliang
Published: July 2019

Laser scanning is an effective tool for acquiring geometric attributes of trees and vegetation, which lays a solid foundation for 3-dimensional tree modelling. Existing studies on tree modelling from laser scanning data are vast. Nevertheless, some works don’t ensure sufficient modelling accuracy, while some other works are mainly rule-based and therefore highly depend on user inputs. In this paper, we propose a novel method to accurately and automatically reconstruct tree branches from laser scans. We first extract an initial tree skeleton from the input tree point cloud, then simplify the skeleton through iteratively removing redundant components. A global-optimization approach is performed to fit a sequence of cylinders to approximate the geometry of the tree branches. Experiments on various types of trees from different data sources demonstrate the effectiveness and robustness of our method. The resulted tree models can be further applied in the precise estimation of tree attributes, urban landscape visualization, etc.
A Wrist Sensor Sleep Posture Monitoring System: An
Automatic Labeling Approach
Authors: Jeng Po-Yuan , Wang Li-Chun , Hu Chaur-Jong , Wu Dean
Published: July 2019

Sleep postures monitoring systems in the hospital aim at transforming sensing signals into quantitative data to characterize the sleep behaviors of the patient. However, a home-care sleep posture monitoring system needs to be user friendly. In this paper, we present iSleePost - a user-friendly home-care intelligent sleep posture monitoring system. We address the labor-intensive labeling issue of traditional machine learning approaches in the training phase. Our proposed mobile health (mHealth) system leverages the communications and computation capabilities of mobile phones for provisioning a continuous sleep posture monitoring service. Our experiments show that iSleePost can achieve 90 percent accuracy in recognizing sleep postures. More importantly, iSleePost demonstrates that an easily-wear wrist sensor can accurately quantify sleep postures.
PENGEMBANGAN MODUL BERBASIS INQUIRY LAB UNTUK MENINGKATKAN KEMAMPUAN MENGANALISIS PADA MATERI SISTEM GERAK KELAS XI IPA
Authors: Karlina Ferida Dwi , Sajidan Sajidan , Karyanto Puguh
Published: July 2019

Tujuan penelitian yaitu: 1) mengetahui karakteristik modul berbasis Inquiry Lab untuk memberdayakan kemampuan menganalisis pada materi sistem gerak, 2) mengetahui kelayakan modul berbasis Inquiry Lab untuk memberdayakan kemampuan menganalisis pada materi sistem gerak, 3) mengetahui keefektivan modul berbasis Inquiry Lab untuk memberdayakan kemampuan menganalisis pada materi sistem gerak di SMA negeri 1 Ngawi. Pengembangan modul berbasis Inquiry Lab mengacu pada 9 langkah model research and development (R&D) dari Borg and Gall meliputi: 1) penelitian dan pengumpulan data, 2) perencanaan, 3) pengembangan produk, 4) uji coba produk awal, 5) revisi produk I, 6) uji coba lapangan, 7) revisi produk II, 8) uji coba lapangan operasional, 9) revisi produk akhir. Analisis hasil penelitian menggunakan dua teknik yaitu deskriptif kualitatif dan diskriptif kuantitatif. Hasil penelitian tentang: 1) Karakteristik Modul Biologi Inquiry Lab pada Materi Sistem Gerak yang dikembangkan menggunakan sintak Inquiry Lab, meliputi observasi, manipulasi, generalisa, verifikasi dan aplikasi. Setiap kegiatan pembelajaran siswa di arahkan untuk menemukan konsep melalui aktivitas laboraturium, 2) Hasil validasi Modul Biologi berbasis Inquiry Lab pada materi sistem gerak dapat digunakan sebagai bahan ajar baru di sekolah. Kelayakan didasarkan atas penilaian terhadap modul melalui uji validasi ahli materi 94,80% dengan kualifikasi sangat baik, validasi ahli pengembangan modul 84,21% dengan kualifikasi sangat baik, validasi ahli perangkat 96,55% dengan kualifikasi sangat baik, validasi ahli keterbacaan 75% dengan kualifikasi baik. Uji kelompok kecil pengguna lapangan (guru dan siswa), validator praktisi (guru) 90,06% dengan kualifikasi sangat baik, dan uji dari lapangan terbatas 81,88% dengan kualifikasi sangat baik, dan uji  keefektifan yang telah sesuai dengan tujuan pengembangan, 3) Keefektifan Modul Biologi berbasis Inquiry Lab pada materi sistem gerak telah efektif dalam memberdayakan kemampuan menganalisis siswa karena menunjukkan adanya perbedaan hasil posttest antara kelas modul dan kelas exiting learning dengan nilai Sig.=0.000 < α=0.05 dengan rata-rata masing-masing kelas modul 75,83 dan kelas exiting learning 69,83.
TECHNOLOGICAL PEDAGOGICAL AND CONTENT KNOWLEDGE (TPACK) FOR OVERCOMING TEACHER PROBLEMS IN VOCATIONAL EDUCATION AND CHALLENGES IN THE 21ST CENTURY
Authors: Fahrurozi Slamet Kurniawan , Budiyanto Cucuk Wawan , Roemintoyo Roemintoyo
Published: July 2019

Lately, students have grown up in the environment with technology as one of the important components that become a necessity that cannot be separated from daily activities, including the integral role of technology in the modern class. Although technology can play an important role in restructuring teaching and learning practices, teachers must take a leading role in designing the right learning environment, and carefully choose effective learning media with the aim of getting technology that can facilitate students to learn well. Society has changed from a conventional model of moving information-based, which results in an emphasis on different knowledge and skills. When entering the world of profession, a teacher is expected to be able to prepare students' skills to face the 21st century using digital technology. The method used uses a systematic literature review. The purpose of this literature review is to dig deeper into the issues and challenges in integrating Technological Pedagogical and Content Knowledge (TPACK) for Professional Teacher Development in the 21st century. This literature review reviews research on TPACK and other literature that reviews the development of quality professional teachers. The findings show that TPACK has a good impact on improving services in teaching and learning to become professional teachers.
A tecnologia nos torna melhores ou apenas adia nosso dilema moral? O caso dos xenotransplantes
Authors: Shikida Cláudio , Araujo Jr. Ari
Published: July 2019

Objetivo: A obtenção do número adequado de órgãos cadavéricos para transplantes é um item de política pública importante. Modelos econômicos tradicionais supõem que a solução pode ser obtida por incentivos financeiros. Críticos dessa abordagem insistem que o mercado não resolve o problema, mas a intervenção estatal sim. Métodos: Este artigo apresenta o modelo do homo economicus maturus de Frey (1997), cujo principal mérito é mostrar que ambas as críticas estão incorretamente colocadas, pois indivíduos respondem não apenas a incentivos monetários de forma positiva, como demonstram os modelos tradicionais, mas também podem apresentar reações psicológicas adversas. Esse modelo é aplicado ao dilema da doação de órgãos com a inclusão do fator tecnológico, por meio da substituição de órgãos humanos por órgãos não humanos (xenotransplantes). Resultados: O principal resultado do artigo é mostrar como um avanço tecnológico pode melhorar o bem-estar sem alterar o dilema moral dos indivíduos. Conclusões: A extensão do modelo econômico tradicional permite uma análise com novas possibilidades acerca de mudanças tecnológicas e dos dilemas morais que elas podem trazer.
Custos adicionais da pessoa com deficiência física – São Paulo e Brasil
Authors: Kanikadan Paula , Yuba Tania , Maior Izabel , Borger Fernanda , Campino Antonio Carlos
Published: July 2019

Objetivo: Calcular os custos adicionais da pessoa com deficiência física e investigar o seu impacto na renda familiar. Métodos: Seguindo a Classificação Internacional de Funcionalidade, identificaram-se quatro perfis de deficiência com graus diferentes de severidade quanto à mobilidade dos membros inferiores e superiores. Foi construída uma matriz de necessidades para estimar os custos adicionais, seguindo o Método de Padrão Orçamentário, a partir de grupos focais. Dados foram coletados em 2013. Utilizou-se o salário mínimo nacional de 2015 (R$ 816,52) para estimar os custos. Resultados: Os custos adicionais variaram de 2 a 14 vezes o salário mínimo nacional. O perfil de menor custo adicional foi o 2, seguido do 1, 3 e 4. O perfil 4 foi o de maior custo adicional devido à grande incapacidade das pessoas. Há exigência de alta intensidade de assistência pessoal e de oferta de equipamentos. Na assistência pessoal, calculou-se o trabalho dos cuidadores dividindo-o por um período de 2, 4, 8 e 24 horas, para São Paulo, Rio de Janeiro, Santa Catarina, Paraná e Brasil. Os custos com assistência pessoal são relevantes no total dos custos e variam conforme a região. Conclusões: Demonstrou-se que há um custo adicional para as pessoas com deficiência física em todos os perfis. Há risco de empobrecimento porque esses custos absorvem a renda dessas pessoas e de sua família, a qual não pode gastar em outros serviços. A renda pode ser, assim, insuficiente para as necessidades primordiais, ficando clara a necessidade de políticas públicas para prover serviços necessários ou benefícios financeiros.
Farmacoeconomia: gastos com análogos de insulina adquiridos por meio de judicialização em um município do estado do Pará, Brasil, no ano de 2016
Authors: Pinheiro Priscila , Garcia João Victor , Cardoso Érica , Luz Diandra , Silva Valdenira
Published: July 2019

Objetivo: Analisar os gastos com insulinas análogas de ação rápida e longa, no município de Belém/PA, no ano de 2016. Métodos: Trata-se de um estudo descritivo, quantitativo de farmacoeconomia, relacionado aos custos de insulinas análogas. A pesquisa foi realizada na Secretária Municipal de Saúde de um município do estado do Pará, por meio da análise das notas de empenho referentes à aquisição de insulinas análogas no ano de 2016. Os dados foram tabulados no Microsoft® Excel 2010, no qual também foram geradas tabelas e gráficos para melhor interpretação das informações coletadas. A presente pesquisa não envolveu a participação de seres humanos e nem a utilização de dados secundários, por isso não houve a necessidade de submissão ao Comitê de Ética em Pesquisa (CEP). Resultados: Durante o ano de 2016, foram disponibilizadas 15 variedades de apresentação de análogos de insulinas. Neste ano, foram realizadas 10 compras de insulinas comprovadas por meio de empenho, resultando num total de 30.450 frascos de insulina, que gerou uma despesa extra de R$ 1.857.778,00 ao município. Em relação à quantidade comprada e ao custo de cada insulina análoga, a insulina Glargina liderou o ranking em ambas as variáveis, obtendo 12.650 frascos comprados e custo total de R$ 967.970,00. Conclusão: Mesmo com a recente inclusão nas listas-padrão de algumas insulinas análogas que devem ser disponibilizadas pelo Sistema único de Saúde (SUS), essa ação ainda não ocorre de maneira efetiva no território brasileiro, evidenciado pelos gastos significativos com a compra de insulinas análogas por meio de judicialização.
Revisão e proposta para atualização da diretriz metodológica de análise de impacto orçamentário de tecnologia em saúde para o SUS
Authors: Costa Márcia , Luna Leonardo , Leite Pedro Henrique , Tura Bernardo , Pinto Márcia , Santos Marisa
Published: July 2019

Objetivos: Fazer uma proposta para atualização da diretriz com maior padronização dos métodos e realizar análise crítica dos pontos considerados mais relevantes para a formulação de um estudo de análise de impacto orçamentário. Métodos: Revisão da literatura, extração de dados, seleção de etapas básicas para a execução de uma análise de impacto orçamentário, apresentação dos resultados para debate com especialistas. Resultados: Foram recuperados 1.215 títulos, dos quais seis foram elegíveis para síntese qualitativa e definição da estrutura analítica para projetar e construir um modelo de impacto orçamentário: perspectiva da análise; estimar a população-alvo; horizonte temporal; taxa de incorporação da nova tecnologia ao mercado (market share); estimar os custos; fontes de dados; taxa de desconto e apresentação do resultado final. Recomendações: perspectiva da análise deve ser a do pagador; estimativa da população elegível a partir de dados epidemiológicos oriundos do Instituto Brasileiro de Geografia e Estatística (IBGE) preferencialmente; horizonte temporal de dois a cinco anos; buscar a taxa de incorporação em órgãos oficiais; custos diretos estimados a partir da autorização de internação hospitalar e portais de compras governamentais; fontes de dados oficiais e apresentação de resultados em tabela e o impacto incremental ano a ano. Conclusões: Avaliação de Impacto Orçamentário é uma ferramenta feita para auxiliar o gestor, que prima por tentar garantir equilíbrio fiscal ao sistema diante das inúmeras demandas da sociedade. Essa característica é fundamental no mundo atual, onde transparência e a responsabilidade nos gastos são exigências cada vez mais frequentes por parte do cidadão
Analysis of supply side factors influencing employability of new graduates: A tracer study of Bahir Dar University graduates
Authors: Fenta Haile Mekonnen , Asnakew Zeleke Siraye , Debele Petros Kibebew , Nigatu Sifelig Taye , Muhaba Aragaw Mulu
Published: July 2019

The purpose of this study was to determine the job placement profiles of the graduates of Bahir Dar University and the relevance of school-related factors to job placement. The study was conducted at Bahir Dar University with participants who were first-degree graduates from the 2015 and 2016 cohorts. Stratified multistage random sampling was used to select respondents. Out of 4208 graduates, 867 graduates were selected to participate in the study. To determine the potential factors for graduate employability in the labour market, both descriptive and inferential statistics were applied.Results revealed that 79% percentof surveyed graduates were gainfully employed, with the majority (93%) having their first job related to their completed course. The time taken to find employment was from 1 to 6 months and the overall average duration of unemployment was 5.08 months. Sixty five percent of graduates reported that they used a public advertisement to find their first job and 58% reported that their employers used examinations to select   potential candidates. A 12% variation in employability was explained by CGPA, preferred field of study, the number of companies contacted and time management skills of graduates. Moreover, graduates’ transitional employability has a positive association with cumulative GPA, preferred field of study, and internship practice. It is recommended that sustainable employment of graduates can be secured if the University improves its current curriculum to incorporate more employability skills demanded by the labour market.
Validity of Arm-Span to estimate height in older adults: a secondary analysis of a Colombian cohort, SABE Bogotá study
Authors: Borda Miguel Germán Borda , Cano-Gutierrez Carlos , Lozano María Juliana , Aruachan Samir , Castellanos-Perilla Nicolás , Pérez-Zepeda Mario Ulises , Reyes-Ortiz Carlos A.
Published: July 2019

Background

Body composition and height changes with aging which brings challenges in order to obtain accurate measures in this population, height measurement is of great importance both in nutritional and clinical assessment in the elderly, and it has been widely used for obtaining values such as body mass index, the aim of this study was to assess the validity of arm span to estimate height in Colombian older adults.

Methods

This is a secondary analysis of the SABE-Bogota study (2012); which is a cross-sectional survey conducted in older adults over the age of 60; with a final sample n=1,436. Spearman`s Rho correlation coefficient was used to assess concurrent validity, while limits of agreement were set through Bland-Altman plots. Criterion validity was performed comparing face-to-face measured height with arm-span estimated height with linear regressions (R2 and SEE).

Results

There was a significant correlation between measured height and arm span estimated height of 0.856 (CI 95% 0.842-0.870; p<0.0001). Limits of agreement ranged between -7.65 and 11.14cm. R2values ranged between 0.3 and 0.8, SEE was lower in males between 60 and 79 years of age.

Conclusions

Alternatives to estimate height in older adults are necessary. Our results suggest that the arm span is a valid measure for the estimation of measured height in Colombian older adults.
The relationship between Fear of Hypoglycemia and Sleep Quality among type II Diabetic Patients
Authors: Yekefallah Leili , Talebi Farzaneh , Razaghpoor Ali , Mafi Mohammmad Hossein
Published: July 2019

Introduction and Objective

Fear of hypoglycemia can result in anxiety, stress, anger, depression and severe avoidance behaviors that it affects the sleep quality of diabetic patients. Therefore, the present study was conducted with the aim of investigating the relationship between fear of hypoglycemia and sleep quality among type II diabetic patients.

Methods

The present cross-sectional study was conducted on 400 type II diabetic patients referred to endocrinology clinic of Velayat Hospital and Boali Hospital in Qazvin, in 2018. Data were collected using a checklist for demographic variables, the Fear of Hypoglycemia Survey (FHS-W), and the Pittsburgh sleep quality index (PSQI). Descriptive statistics and Spearman correlation test were performed for data analysis using SPSS v24.

Results

In this study, the mean age of diabetic patients was 55.75±10.31. The majority of the participants were female (n=299, 74.8%) and were treated with oral anti-diabetic drugs (n=174, 43.5%). The mean score of sleep quality in patients was 8.98±3.64 and the fear of hypoglycemia was 21.27±11.92. The results of this study showed that there was a significant relationship between the fear of hypoglycemia and the poor sleep quality among patients (p<0.001, r=0.305).

Conclusion

The fear of hypoglycemia has a direct and significant relationship with poor sleep quality in diabetic patients; so that this fear reduces the quality of sleep in diabetic patients. Therefore, in order to provide adequate sleep to prevent inappropriate sleep complications, great attention should be paid to the issue of fear of hypoglycemia, and consider some actions to reduce this fear.