bluuebunny/crossref_metadata_2025 huggingface dataset:
Mål, middel og tid – om livsformsanalysen som metode til at studere tilgangen til nyheder og aktualitetsstof
Authors: Johansen Jakob Dybro , Jensen Jakob Linaa
Published: January 2022

Denne artikel beskæftiger sig med danskernes opfattelse af nyheder. I modsætning til gængse studier af danskernes nyhedsbrug graver den et spadestik dybere og undersøger forskellige befolkningsgruppers opfattelser af nyheder: hvad ser man som nyheder, og hvilken rolle spiller de i dagliglivet og forholdet til andre borgere og samfundet. Undersøgelsen er baseret på dybdegående interviews med 101 borgere og et efterfølgende survey blandt 2000 tilfældigt udvalgte respondenter. I undersøgelsen vises det, at kendte faktorer som uddannelse, social status og familieforhold kun i nogen omfang forklarer forskellige tilgange til nyheder. I stedet er forholdet afhængigt af en lang række personlige og hverdagslige faktorer. Derfor forsøger vi med begreber om mål, middel og tid hentet fra Thomas Højrups livsformsanalyse at genanalysere vores materiale. Vi finder, at mål-middel-relationen og især forholdet til tid (og manglende tid) er afgørende faktorer i at forklare forskellige tilgange til nyheder. Til sidst i artiklen går vi tilbage og reflekterer over livsformsanalysens anvendelighed til at supplere eksisterende tilgange til studiet af nyheder og giver bud på fremtidige anvendelser i konkrete projekter.

 

NØGLEORD:
Le récit colonial des voyageuses françaises : aux frontières de l’imaginaire et de la réalité
Authors: Sánchez Diosdado Juan Manuel
Published: January 2022

La visée du présent article est d’analyser les récits des voyageuses françaises qui se sont inspirées du Maroc de la première moitié du XXème siècle. Un type de littérature capable de refléter deux types d’images sur le Maroc colonial, des regards sur un milieu onirique et imaginaire où les odeurs et les couleurs se fusionnent harmonieusement, sur le flamboiement quasi absolu des ornements arabesques et sur les silhouettes excitantes et licencieuses des odalisques. D’autres regards sur le réalisme cru et dissonant des villages paumés, sur le paupérisme visible dans les ruelles enchevêtrées d’une vieille médina, sur l’avilissement physique et psychique des esclaves, sur le mystère que cache l’intérieur d’une kasbah délabrée. Deux images dissemblables, susceptibles de s’enlacer en créant une représentation globale sur le Maroc de l’époque coloniale.
Jeux et enjeux du métissage linguistique et culturel dans 'Verre Cassé' d’Alain Mabanckou
Authors: Soltani Feyrouz
Published: January 2022

Scruter la production littéraire des écrivains africains de la Migritude amène, immédiatement, à une notion-clé à savoir l’hybridité. En effet, la narration africaine contemporaine renverse toutes les normes de l’écriture traditionnelle et stipule le plurilinguisme et le pluriculturalisme. C’est dans cette perspective que la présente contribution propose de mettre en lumière les modalités et les en (jeux) de l’hybridité dans Verre Cassé d’Alain Mabanckou. Il sera question, en premier lieu, de déceler les indices de la rupture esthétique et culturelle. En deuxième lieu, nous viserons à démontrer que l’hybridité dans ce récit, considéré comme un puzzle intertextuel, véhicule une revendication identitaire grâce à l’emploi des structures lexicales, grammaticales et sémantiques hybrides.
Créer pour mieux voir : Image(s) du sida et enjeux de la représentation dans '120 battements par minute'
Authors: Chareyron Romain
Published: January 2022

À travers l’analyse du film de Robin Campillo 120 battements par minute (2017), cet article se propose d’interroger le rôle des images dans notre conceptualisation de l’épidémie de sida. En choisissant de porter à l’écran un pan de l’histoire française récente dont la fiction s’est peu emparée – les lutte menées par Act Up-Paris durant les années 1990 – le film s’attache à effectuer un réexamen du passé du point de vue de celles et ceux qui ont combattu pour une plus grande justice sociale mais qui ont longtemps été relégués aux marges. Comme le montrera cet article, en prenant pour sujet une association dont le message politique reposait en grande partie sur l’image qu’elle véhiculait et qui se voulait un contrepoids aux discours politique et médical de l’époque, le film participe d’une mise en abyme des enjeux de la représentation et du regard qu’elle induit. Cela nous amènera à réfléchir sur la force du visuel à incarner un message, ainsi que sa capacité à nous amener à penser le monde social. Nous nous intéresserons plus particulièrement à la relation entre image, mémoire et connaissance à travers une analyse sémiotique de l’image filmique qui nous permettra de mettre en avant le phénomène de réflexivité à l’œuvre au sein du film. Dans cette optique, nous observerons la manière dont Campillo crée des images qui ont une fonction double : mettre à jour la convergence de l’intime et du collectif qui irriguait les actions d’Act Up-Paris et donnait au visuel sa force contestataire, tout en inscrivant sa propre représentation dans une démarche mémorielle dont le but est d’enrichir nos connaissances vis-à-vis du sida et des luttes menées par des individus trop longtemps « invisibilisés ».
Entre décélération et pleine habitation du temps : 'Serial fucker. Journal d’un barebacker' d’Érik Rémès
Authors: Bessette Ariane
Published: January 2022

Cet article propose l’analyse de la thématique du temps dans l’écriture du sida, en montrant les mutations que cet enjeu subit des œuvres pionnières aux plus récentes, liées au « post-sida ». En observant la vision et l’intériorisation du temps dans Serial fucker. Journal d’un barebacker d’Érik Rémès, nous voyons comment le barrage qu’opposent les trithérapies à l’anticipation de la mort engendre l’élaboration d’un mode de vie basé sur l’intensité et la fulgurance, lesquelles modélisent le fond (notamment l’enjeu du barebacking) et la forme (mise en discours subversive et métatopique) du récit thanatographique.
Avant-propos: Sida, une épidémie presque oubliée
Authors: Lestrade Didier
Published: January 2022

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El uso expresivo de las palabras: Daño sexual, narración y transformación
Authors: Corbí Josep , Martinez Saez Carmen
Published: January 2022

Resumen: Marta Suria escribe Ella soy yo como parte de su respuesta a la irrupción del recuerdo de las agresiones sexuales que había sufrido desde su infancia. Confía en que la forma en que narra su experiencia, la transforme y la libere. ¿Cómo es posible, sin embargo, que una forma de narrar nos transforme, tenga el poder de liberarnos? En este escrito, describiremos, primero, la concepción de la relación entre lenguaje y experiencia que da pie a esta perplejidad; esbozaremos, posteriormente, una concepción alternativa en la que esa perplejidad se disuelve y desde la que es fácil reconocer el poder transformador de ciertas formas de narrarnos. Descansará esta concepción alternativa en la idea de expresión y en la capacidad de percibir aspectos. Mostraremos, en primer lugar, que el lenguaje no solo sirve para describir o para valorar nuestra experiencia, sino también para expresarla; argumentaremos, posteriormente, que la expresión lingüística o gestual de una experiencia no solo la anuncia o manifiesta, sino que le da forma y la modula; subrayaremos, finalmente, el poder transformador de ciertos usos expresivos del lenguaje.
Abstract: Marta Suria writes Ella soy yo as part of her response to the irruption of the memories of the sexual aggressions she had suffered since childhood. She is convinced that the way she narrates her experience will transform and liberate her. How is it at all possible that a certain kind of narrative may transform and liberate us? In this paper, we will first describe the conception of the relationship between language and experience that lies behind this perplexity and, secondly, we will sketch an alternative conception that will hopefully allow us to account for the transformative power of certain kinds of narratives. This alternative conception will hinge on the idea of expression and on the concept of aspect perception. For this purpose, we will firstly argue that language can be used not only to describe or evaluate our experience, but also to express it; we will, then, defend the view that linguistic or gestural expressions of our experiences not only announce or manifest them, but contribute to shaping and modulating them; finally, we will highlight the transformative, humanizing power of certain expressive uses of language.
Palabras clave: daño sexual, narración, expresión, percepción de aspectos, escena de triangulación, jugar, transformación.
Keywords: sexual harm, narrative, expression, aspect perception, scene of triangulation, playing, transformative.
¿Qué es una emoción?
Authors: Cabrera Miquel Marta
Published: January 2022

Resumen: El objetivo de este artículo es realizar un repaso de las teorías de las emociones más importantes de las últimas décadas y valorar en qué medida tales teorías ofrecen una buena caracterización del fenómeno en cuestión. Para alcanzar una comprensión adecuada de las diferentes teorías, así como del rumbo que ha tomado el debate actual sobre las emociones, es importante que prestemos especial atención a algunos de los compromisos filosóficos involucrados en la formulación de estas teorías. La revisión cuidadosa de algunos de estos compromisos nos llevará a plantearnos si algunas de las dificultades a las que se enfrentan varias de las teorías de las emociones actuales podrían tener origen en tales compromisos filosóficos y no, como suele pensarse, en la complejidad de las emociones.
Abstract: The aim of this paper is to review the most important theories of emotions in recent decades and to assess the extent to which these theories provide a good characterisation of the phenomenon in question. In order to achieve an appropriate understanding of the different theories, as well as of the direction that the current debate on emotions has taken, it is important that we pay special attention to some of the philosophical commitments involved in the formulation of these theories. Careful examination of some of these commitments will lead us to consider whether some of the difficulties faced by several of the current theories of emotions might stem from such philosophical commitments rather than, as is often thought, from the complexity of emotions.
Palabras clave: episodios, intencionalidad, fenomenología, propiedades evaluativas.
Keywords: episodes, intentionality, phenomenology, evaluative properties.
Despolitización del feminismo en los discursos gerenciales
Authors: Ávila Bravo-Villasante María
Published: January 2022

Resumen: En su libro Mujeres y discursos gerenciales. Hacia la autogestión feminista (2020), María Medina-Vicent aborda desde una perspectiva crítica feminista los discursos gerenciales dirigidos a las mujeres, desvelando el androcentrismo y la presencia —y perpetuación— de tradicionales roles y estereotipos de género en los modelos de gestión. Mi propuesta pretende incidir en dos aspectos del análisis realizado por Medina-Vicent, por un lado, remarcar los peligros de la despolitización de los discursos gerenciales dirigidos a mujeres —sobre todo en tanto que la literatura gerencial acaba por informarnos a todas—. Por otro, profundizar en la crítica que la autora realiza de la cooptación del feminismo por parte de estos discursos.
Abstract: In her book Mujeres y discursos gerenciales. Hacia la autogestión feminista (2020), Medina-Vicent approaches management discourses aimed at women from a critical feminist perspective, revealing the androcentrism and the presence and perpetuation of traditional gender roles and stereotypes in management models. My proposal aims to highlight two aspects of Medina-Vicent’s analysis: on the one hand, to highlight the dangers of depoliticizing management discourses aimed at women - especially insofar as management literature ends up informing us all. On the other hand, the author’s critique of the co-optation of feminism by these discourses will be explored in greater depth.
Palabras clave: discursos gerenciales, teoría feminista, antifeminismo, despolitización.
Keywords: managerial discourses, feminist theory, antifeminism, depoliticization.
Intimidad, autenticidad y estereotipos en los discursos gerenciales dirigidos a mujeres
Authors: De Tienda Palop Lydia
Published: January 2022

Resumen: El feminismo contemporáneo debe responder a la pregunta clásica acerca de qué significa ser una mujer con el fin de perfilar los cauces de su nueva andadura. Partiendo de tres tesis que sostiene María Medina-Vicent en su obra Mujeres y discursos gerenciales. Hacia la autogestión feminista me propongo reflexionar sobre el dilema actual, que enfrentan las mujeres, marcado por la dialéctica entre la dimensión individual y la colectiva.
Abstract: Contemporary feminism must answer the classic question about what it means to be a woman in order to outline the channels of its new path. Starting at three claims made by María Medina-Vicent in her book Mujeres y discursos gerenciales. Hacia la autogestión feminista, I reflect on the current dilemma, faced by women, with the dialectic between the individual and the collective dimension.
Palabras clave: cultura, sexo, género, rol, intimidad, autenticidad, narrativas, estereotipos.
Keywords: culture, sex, gender, role, intimacy, authenticity, narratives, stereotypes.
El uso del dispositivo en el estudio de los discursos gerenciales
Authors: Muñoz-Rodríguez David
Published: January 2022

Resumen: En el marco del estudio de los discursos gerenciales, se destacan en el presente texto algunas de las aportaciones de Medina-Vicent (2020), especialmente el análisis de los procesos de individualización y despolitización de mensajes que entroncarían con las reivindicaciones del feminismo. En este contexto, se propone la incorporación del concepto foucaultiano de dispositivo para el estudio de los elementos que contribuyen a la difusión de los discursos gerenciales. Este concepto podría ser de utilidad en la investigación empírica, proporcionando una herramienta conceptual para estudiar como un sistema homogéneo de relaciones de saber y poder los distintos elementos que conformarían el dispositivo gerencial.
Abstract: Within the framework of the study of managerial discourses, this text highlights some of the contributions of Medina-Vicent (2020), especially the analysis of the processes of individualization and depoliticization of messages that are linked to the claims of feminism. In this context, the incorporation of the Foucauldian concept of dispositif is proposed for the study of the elements that contribute to the diffusion of managerial discourses. This concept could be useful in the empirical analysis, as well as providing a conceptual tool to study the different elements that make up the managerial dispositif as a homogeneous system of knowledge and power relations.
Palabras clave: gerencialismo, dispositivo, herramientas disciplinarias.
Keywords: managerialism, dispositif, disciplinary instruments.
Ideologías empresariales y postfeminismo: Un diálogo interdisciplinar
Authors: Medina-Vicent Maria
Published: January 2022

Resumen: Este texto es una respuesta abierta a las apreciaciones planteadas por las profesoras María Ávila Bravo-Villasante y Lydia de Tienda Palop, y los profesores Carlos Jesús Fernández Rodríguez y David Muñoz Rodríguez a la obra Mujeres y discursos gerenciales. Hacia la autogestión feminista (Medina-Vicent 2020). A lo largo de las presentes páginas se busca articular un diálogo entre miradas procedentes de diferentes disciplinas (filosofía, sociología y teoría feminista centralmente) que contribuya a enriquecer la reflexión elaborada en dicha obra y abrir nuevos interrogantes sobre la misma. A su vez, dicho diálogo permitirá seguir ampliando el campo de los estudios del management desde la perspectiva feminista.
Abstract: This is an open response to the comments of professors María Ávila Bravo-Villasante, Lydia de Tienda Palop, Carlos Jesús Fernández Rodríguez, and David Muñoz Rodríguez to the book Mujeres y discursos gerenciales. Hacia la autogestión feminista (Medina-Vicent 2020). The aim is to articulate a dialogue among views from different disciplines (centrally philosophy, sociology and feminist theory) that can contribute to enrich the reflection elaborated in the book and to open new questions about it, with the hope that this dialogue will help to expand the field of management studies from a feminist perspective.
Palabras clave: postfeminismo, mujeres, liderazgo, gestión.
Keywords: postfeminism, women, leadership, management.
Necrolytic erythema migrans in celiac disease
Authors: Ryme Dassouli , BayBay Hanane , Choukri Souad , Douhi Zakia , Elloudi Sara , Mernissi Fatima Zahra
Published: January 2022

Erythema migrans necrolytica is a red, blistering rash that spreads over the skin. It particularly affects the skin around the mouth and distal extremities, but can also be found on the lower abdomen, buttocks, perineum and groin. It is strongly associated with glucagonoma, a glucagon-producing tumor of the pancreas, but is also seen in a number of other conditions, including liver disease and intestinal malabsorption such as celiac disease. We present a case of a patient with a history of poorly followed celiac disease presenting with a clinical picture of ENM. This rare case adds to our understanding of the clinical presentation of NME, as well as highlights the importance of acting in a timely manner to avoid the most redoubtful complications.
Simulation of hollow cathode discharge in oxygen
Authors: Zhao Li-Fen , Ha Jing , Wang Fei-Fan , Li Qing , He Shou-Jie ,   College of Physics Science and Technology, Hebei University, Baoding 071002, China,   College of Science, Hebei Agricultural University, Baoding 071002, China,   Institute of Electrostatic Technology, Hebei University, Baoding 071002, China
Published: January 2022

The characteristics, the formations and loss mechanisms of different particles of hollow cathode discharge in oxygen at 266 Pa are investigated by using the fluid model. The model contains 11 kinds of particles and 48 reactions. Under this simulation condition, the negative glow regions corresponding to the surrounding cathodes overlap. The results show that there is a strong hollow cathode effect. The density distributions of different charged and active particles are calculated. The charged particle density is located mainly in the central region of the discharge cell. Electrons and O– are the main ingredients of negative charges in the discharge system, and their density peaks are 5.0 × 1011 cm–3 and 1.6 × 1011 cm–3, respectively and \begin{document}${\rm{O}}_2^+ $\end{document} is a main composition of positive charge in the discharge system with a peak density of 6.5 × 1011 cm–3. Abundant active oxygen particles exist in the discharge system, and their density is much higher than those of other charged particles. According to the densities of active particles, their magnitudes are ranked in the small-to-large order as O, O2(a1Δg), O(1D) and O3. Furthermore, the generation and consumption mechanism of electrons, O– and \begin{document}${\rm{O}}_2^+ $\end{document} are calculated in detail, and the generation and consumption paths of different active oxygen particles are also given. The results show that there is a complex coupling process among these particles. Each reaction generates a certain number of particles and consumes other particles at the same time, resulting in a dynamic balance among these particles.
Tentacle patterning during Exaiptasia diaphana pedal lacerate development differs between symbiotic and aposymbiotic animals
Authors: Presnell Jason S. , Wirsching Elizabeth , Weis Virginia M.
Published: January 2022

Exaiptasia diaphana, a tropical sea anemone known as Aiptasia, is a tractable model system for studying the cellular, physiological, and ecological characteristics of cnidarian-dinoflagellate symbiosis. Aiptasia is widely used as a proxy for coral-algal symbiosis, since both Aiptasia and corals form a symbiosis with members of the family Symbiodiniaceae. Laboratory strains of Aiptasia can be maintained in both the symbiotic (Sym) and aposymbiotic (Apo, without algae) states. Apo Aiptasia allow for the study of the influence of symbiosis on different biological processes and how different environmental conditions impact symbiosis. A key feature of Aiptasia is the ease of propagating both Sym and Apo individuals in the laboratory through a process called pedal laceration. In this form of asexual reproduction, small pieces of tissue rip away from the pedal disc of a polyp, then these lacerates eventually develop tentacles and grow into new polyps. While pedal laceration has been described in the past, details of how tentacles are formed or how symbiotic and nutritional state influence this process are lacking. Here we describe the stages of development in both Sym and Apo pedal lacerates. Our results show that Apo lacerates develop tentacles earlier than Sym lacerates, while over the course of 20 days, Sym lacerates end up with a greater number of tentacles. We describe both tentacle and mesentery patterning during lacerate development and show that they form through a single pattern in early stages regardless of symbiotic state. In later stages of development, Apo lacerate tentacles and mesenteries progress through a single pattern, while variable patterns were observed in Sym lacerates. We discuss how Aiptasia lacerate mesentery and tentacle patterning differs from oral disc regeneration and how these patterning events compare to postembryonic development in Nematostella vectensis, another widely-used sea anemone model. In addition, we demonstrate that Apo lacerates supplemented with a putative nutrient source developed an intermediate number of tentacles between un-fed Apo and Sym lacerates. Based on these observations, we hypothesize that pedal lacerates progress through two different, putatively nutrient-dependent phases of development. In the early phase, the lacerate, regardless of symbiotic state, preferentially uses or relies on nutrients carried over from the adult polyp. These resources are sufficient for lacerates to develop into a functional polyp. In the late phase of development, continued growth and tentacle formation is supported by nutrients obtained from either symbionts and/or the environment through heterotrophic feeding. Finally, we advocate for the implementation of pedal lacerates as an additional resource in the Aiptasia model system toolkit for studies of cnidarian-dinoflagellate symbiosis.
Identifying and prioritising climate change adaptation actions for greater one-horned rhinoceros (Rhinoceros unicornis) conservation in Nepal
Authors: Pant Ganesh , Maraseni Tek , Apan Armando , Allen Benjamin L.
Published: January 2022

Climate change has started impacting species, ecosystems, genetic diversity within species, and ecological interactions and is thus a serious threat to conserving biodiversity globally. In the absence of adequate adaptation measures, biodiversity may continue to decline, and many species will possibly become extinct. Given that global temperature continues to increase, climate change adaptation has emerged as an overarching framework for conservation planning. We identified both ongoing and probable climate change adaptation actions for greater one-horned rhinoceros conservation in Nepal through a combination of literature review, key informant surveys (n = 53), focus group discussions (n = 37) and expert consultation (n = 9), and prioritised the identified adaptation actions through stakeholder consultation (n = 17). The majority of key informants (>80%) reported that climate change has been impacting rhinoceros, and more than 65% of them believe that rhinoceros habitat suitability in Nepal has been shifting westwards. Despite these perceived risks, climate change impacts have not been incorporated well into formal conservation planning for rhinoceros. Out of 20 identified adaptation actions under nine adaptation strategies, identifying and protecting climate refugia, restoring the existing habitats through wetland and grassland management, creating artificial highlands in floodplains to provide rhinoceros with refuge during severe floods, and translocating them to other suitable habitats received higher priority. These adaptation actions may contribute to reducing the vulnerability of rhinoceros to the likely impacts of climate change. This study is the first of its kind in Nepal and is expected to provide a guideline to align ongoing conservation measures into climate change adaptation planning for rhinoceros. Further, we emphasise the need to integrating likely climate change impacts while planning for rhinoceros conservation and initiating experimental research and monitoring programs to better inform adaptation planning in the future.
Detección de barreras e implementación de procedimientos para reducir la demora en el tratamiento del síndrome coronario agudo con elevación del segmento ST mediante angioplastia primaria. Experiencia de 20 años de un centro de referencia en una ciudad de alta densidad demográfica
Authors: Blanco Federico , Szarfer Jorge , García Escudero Alejandro , Albornoz Federico , Alonso Analía , Yurko Vielka , Affatato Susana , Feldman Matías , Gigena Gerardo
Published: January 2022

Background: The delay to reperfusion of ST-segment elevation acute coronary syndrome (STEACS) is a key factor in its prognosis, and its reduction could reduce morbidity and mortality. Objective: The aim of this study was to identify and modify the barriers detected in 20 years of STEACS treatment in a tertiary care center of a densely populated city to evaluate their effect on the outcome of the procedure. Methods: A total of 3007 patients with STEACS within 12 hours of symptoms onset were prospectively and consecutively included to undergo primary percutaneous coronary intervention (PCI) from January 1, 2000 to December 31, 2019. Time from symptoms onset to balloon inflation was divided into intervals. After barriers were identified (2000-2009), the procedure was changed. The population was divided into two groups (G) G1: pre-implementation (2000-2009) and G2: post-implementation (2010-2019) of changes. Results: G1 included 1409 and G2 1598 patients with no demographic differences except for the type of PCI. Delays were identified in diagnosis, communication between physicians, transfer and admission of the patient to the hemodynamics lab. Procedural changes decreased first medical contact-hemodynamic team contact interval [G1: 90 min (36-168) vs. G2: 77 min (36-144) p –0.01] and hemodynamic team contact-hemodynamics lab admission interval [G1: 75 min (55-100) vs. G2: 51 min (34-70) p –0.01] and reduced in-hospital (G1: 9,2% vs. G2: 6,7% p –0,01) and 6-month (G1: 13.1% vs. G2: 7.5% p –0. 01) mortality. Conclusions: Delay in diagnosis, difficulty in communication and type of transfer were the most important causes of delay. Implementing a procedural protocol reduced delays. Continuous evaluation of results and permanent education constitute the fundamental cornerstones for optimizing network care programs
Hacia el esclarecimiento del rol del anión cloruro en la hipertensión arterial: su vínculo con el daño oxidativo en el riñón
Authors: Kouyoumdzian Nicolás M. , Kim Gabriel , Robbesaul Gabriel D. , Prince Paula D. , Puyó Ana M. , Fernández Belisario E. , Galleano Mónica L. , Choi Marcelo R.
Published: January 2022

Introduction: The role of the chloride anion on the deleterious effects of excessive consumption of salt (NaCl) and whether its effects are independent each other of the presence of sodium remains to date, unknown and unclear. Objective: To demonstrate that both a chloride overload and a sodium overload in the diet produce deleterious effects, by different mechanisms, on systolic blood pressure (SBP), renal function and markers of oxidative stress in the kidney. Materials and Methods: Male Wistar rats were divided into four groups (n = 8 / group) and fed with different diets for three weeks: C: control (standard diet), and diets: NaCl: hypersodic-hyperchloric; Na: hypersodic without chloride and Cl: hyperchloric without sodium. Systolic blood pressure (SBP) and renal function were determined, and the production of thiobarbituric acid reactive species (TBARS) and the activity and expression of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) enzymes were evaluated in renal cortex tissue. Results: SBP increased (*) in the two groups fed with chloride. The fractional excretion of sodium and chloride increased (*) in the NaCl and Na groups. increased (*) in the renal cortex with the three diets. No changes were observed in the activity and expression of SOD and CAT. GPx activity increased (*) in the two groups that received chloride; (* p <0.05 vs C). Conclusion: Both sodium and chloride overload are associated with a higher oxidative state characterized by an increase in lipid peroxidation in the renal cortex. However, compared with Na group, only chloride overload is associated with higher GPx activity and hypertension without any changes in urinary chloride excretion, suggesting a higher renal pro-oxidant state in this experimental group.
CLINICAL EFFICACY OF DASHMOOL KWATH NASYA IN THE MANAGEMENT OF MANYASTAMBHA WITH SPECIAL REFERENCE TO CERVICAL SPONDYLITIS
Authors: Mishra Ashish , Gupta Satish Chand , Ahmad Mansoor , Tiwari Bharti
Published: January 2022

Background: Nasya is an essential therapeutic procedure as many of the courses of Ayurvedic treatment. It comes under the Panchashodhana karmas. It is necessary in all Urdhwa jathru vikaras. Nasya is effective for inducing immediate results and serves as a permanent cure. Cervical spondylotic change is frequently found in many asymptomatic adults, with 25 the age of 40, 50% of adults over the age of 40 and 85% of adults over the age of 60 showing evidence of disc degeneration. Cervical spondylosis can be compared with Manyastambha based on signs & symptoms. Nasya is the simple techniques and ingredients are readily available & economical. Also, these are indicated in the management of Manyastambha and have no proven adverse effects. This study was intended to assess the efficacy of the Dashmool Kwath Nasya in the management of this disease. Method: Randomly, 30 patients of Manyastambha were selected and paired “t” test was used. Result: Statistically significant improvement was found in this study on post-follow-up. Conclusion: Dashmool Kwath Nasya is having a prolonged action as it is having highly significant results post follow up of treatment as compared to after treatment.
EFFECT OF COMBINATION OF FRUIT OF BADARA [Ziziphus jujuba (L). Lam] AND PALM JAGGERY IN DYSFUNCTIONAL UTERINE BLEEDING
Authors: Nampoothiri Subha K , Sreedhar Asha , Hameed A Shahul
Published: January 2022

Dysfunctional uterine bleeding (DUB) is a state of abnormal uterine bleeding. It is a diagnosis of excluding any clinically detectable organic, systemic and iatrogenic cause. Current treatments available have many side effects, including hormonal imbalance. So there exists a lacuna for a safe and effective treatment without side effects for this condition. The present study is an effort to evaluate the combined effect of fruit of Badara [Ziziphus jujuba(L). Lam] with Palm jaggery in Dysfunctional uterine bleeding. The study design is interventional with a sample size of 15 subjects within the age group of 16-50 years. The study drug was administered in 6gm in the morning and the evening before food for 90 days. The following 30 days was follow up period without medication. The effect was assessed on subjective and objective parameters before treatment and on the 31st, 61st, 91st and 121st days. The results were statistically analyzed using Paired t-test and Wilcoxon Signed Rank test. The study drug showed the statistically significant result in DUB as reducing the amount and duration of bleeding, an interval of menstruation, number of clots, pain, fatigue, and increasing the Haemoglobin percentage.
Assessment of Knowledge and Attitude Regarding Risk Factors of Malaria Among Caregivers of Under-Five Children in the Buea Health District, South West Region, Cameroon
Authors: Ngouakam Hermann , Akongem Mark Agbor , Cagetan Timatang Tufoin , Ngueugang Ariane Laure Wounang , Tientche Bonaventure , Nsagha Dickson Shey
Published: January 2022

Aims: The study measured the level of knowledge and attitudes towards malaria and examined associated factors among caregivers of under-five children.

Study Design: The study was community-based, descriptive cross-sectional.

Place and Duration of Study: The study was carried out in Buea Health District (BHD) from February to June 2020.

Methodology: Data were obtained through face-to-face interviews with the caregivers of under-fives. The above mean scores were used to determine the level of knowledge. The attitude levels were measured by using 3-point Likert scales. Univariate and multivariate logistic regression analyses were performed to identify risk factors associated with knowledge and attitude. SPSS software version 20.0 was used for analysis.

Results: Out of the 390 respondents, 69.5% of them had a neutral attitude. Meanwhile, 27.7 % of participants carried a favorable attitude towards malaria and only 2.8 % of them had an unfavorable attitude, Caregivers of under-five children who scored below the mean score were 25.1 % which was considered having poor knowledge and above the mean score was 74.9% which was considered good knowledge. In the multivariable logistic analysis, caregivers with a primary school level of education were 4.1 times (AOR = 4.1, CI = 1.486-11.102) times more likely of receiving a high malaria knowledge score as compared to those with no formal education. Factors associated with caregiver's attitude level towards malaria risk were educational level and marital status which showed significant associations in the univariate analysis

Conclusion: Caregivers of under-fives displayed a good knowledge of malaria risk factors. However, in these endemic areas for malaria, caregiver attitude was found to be unenthusiastic and unresponsive, and this poses additional challenges in reaching the malaria elimination goal. Thus, suggesting that educational messages during the campaign should be contextual to reach out to local communities to trigger a positive behavioural change.
Study about Tuberculosis in Thailand: An approach to Treatment, GIS and Sichon Model
Authors: Wongworachat Arak , Nituton Kunagorn , Nithikathkul Choosak
Published: January 2022

In this study, we seek to identify geographical areas where ongoing tuberculosis epidemiological characteristics is occurring by linking Geographic Information Systems (GIS) technology in Thailand. In addition, we seek to assess how the directly observed treatment short-course (DOTS) program improved new tuberculosis diagnosis and treatment successes in Sichon District, Nakhon Si Thammarat province, Thailand from 2014 to 2016. The assessment program included seven indicators, and the results revealed that 73 new cases of tuberculosis were admitted for treatment on average every year, with rates of risk group screening findings of 4.28, 5.23, and 6.04 %, respectively. Patients who come to the hospital for diagnosis make up most of the demographic. However, only a minor proportion of patients are identified through community-based primary screening. In the years 2013-2016, the mortality rate of TB cases is expected to rise by 10.25 %, 4.25 %, and 5.56 %, respectively. The elderly and HIV-positive patients comprise most of the TB mortality population. When completing the DOTS program at a hospital, however, the rate of success has fallen short of the targets. Furthermore, the screening technique excludes the target group. As a result, people suffering tuberculosis are reported to be slower and more susceptible to symptoms. As a result, researchers advise that the DOTS program be supported by enhancing treatment follow-up to improve the effectiveness of TB treatment and collaboration with health care worker (HCW).
Mathematical Modelling of the Drying Characteristics of Milled Sorghum Residue
Authors: Isa J. , Majasan O. I. , Jimoh K. A.
Published: January 2022

During milling of cereal grains, bran which is separated from the starchy endosperm of the grain is a major by-product. In this study, milled sorghum residue was dried in a cabinet dryer under different conditions (temperature and air velocity). The obtained drying data were fitted into ten existing mathematical models and obtained the best model while, the effective moisture diffusivity and activation energy of the drying process was determined using Arrhenius type approach. The result shows that the initial moisture content obtained for the sorghum residue using standard oven drying method were 41.28 ± 0.33%, 49.52 ± 0.63 % and 47.06 ± 0.42 % on wet basis for the wet residue of variety A, B and C, respectively, at equilibrium point, the final moisture content of about 12.93 ± 0.14 – 14.31± 0.07 as temperature ranges from 40 oC to 70 oC and air velocity ranges from 0.8 m/s to 1.2 m/s. During the drying process, the drying rate falls more rapidly as it was initially high as a result of more moisture in the sorghum residue and the drying rate decreases slowly until reaching the reduced moisture content. The obtained values of effective moisture diffusivity (Deff) ranges between 9.89 x 10-10 and 22.21 x 10-10 m2/s, 9.45 x 10-10 and 20.62 x 10-10 m2/s and 8.56 x 10-10 and 20.76 x 10-10 m2/s for variety A, B and C, respectively. However, the result of the modelling shows that the drying characteristics of variety A and B of the sorghum residue can be predicted using Midilli et al. model while the drying behaviour of Variety C can be predicted using Hii et al. model.
Evaluation of Plasma Levels of Interleukin 6 and Iron Status of Football Players in a Nigerian University
Authors: Obeagu Emmanuel Ifeanyi , Amedu Gideon Ojochegbe , Okoroiwu Ijeoma L. , Okafor Chukwuma J. , Okun Ohikhuare , Ochiabuto Ogochukwu M. T. Barbara , Ukeekwe Chukwulete Okafor
Published: January 2022

To determine the levels of interleukin 6 (IL-6) and iron status of football players in Madonna University, Elele, Rivers State, Nigeria. A total number of 100  subjects were recruited for the study, comprising of 50 of football players before playing football (25 males and 25 females) and 50 of football players after playing football (25 males, 25 females) from Madonna University Nigeria, Elele Campus, Rivers State, Nigeria. The data obtained from the study were presented as Mean  SD in tables and analysed using student t-test for parametric data using SPSS version 20. The level of significance was set at p<0.05. The results showed significant increase (p=0.004) in interleukin 6 (IL-6) of football players after playing compared to it before playing and no significant change (p=0.505) in the iron level of football players after playing compared to before playing respectively. The results also showed no significant change in interleukin 6 compared among football players based on gender and age groups and no significant change in the iron level of all the subjects. The study showed increase an in interleukin 6 (IL-6) of the football players after playing compared to the level before playing which shows that the physical activity increases the level of interleukin 6 and but has no effect on the iron level after football game.
Formulation, Characterization and Release Behaviour of Metformin Hydrochloride Modified Release Tablet by Using Hydrophilic Polymers
Authors: Thirumaran J. , Tamilarasi S. , Punitha S. , Sivakumar T. , Marimuthu C. N. , Kiruthika D.
Published: January 2022

Amongst the many public health problems, the diabetes mellitus is considered as a chronic life-style related disease which is now growing as an epidemic in both developed as well as developing countries. The current study is about formulation of metformin hydrochloride tablet to confirm their sustained release property by using various polymers. The tablets are prepared by granulation techniques using binding solution containing polyvinyl pyrolline K30. The possible interaction between the pure metformin hydrochloride and polymers are identified by Fourier transform-infrared spectroscopy. Tablets were formulated with different polymers like Hydroxy propyl methyl cellulose K100 and sodium carboxymethyl cellulose. Matrix prepared with high concentration of HPMC K100 polymer retards the drug release up to 6 h at 59 %, but the formulation 2 (F2) showed 72.72% of drug release in 6 h. The release of drug from the F2 formulation was found to be prolonged drug release when compared to other formulations. Hence our study conclude that the HPMC K100 polymer containing formulation showed good sustained release property owing to the high gel strength and well high viscosity nature of the polymer.
The Prescribing of MEBO Ointment in a Public Hospital in Alkharj
Authors: Ahmed Nehad J. , Almutairi Ahmed H. , Alotaibi Faris A. , Menshawy Menshawy A.
Published: January 2022

Aim: The present study aimed to describe the prescribing of moist exposed burn ointment (MEBO) in Alkharj.

Methodology: This is a retrospective study that includes reviewing the electronic prescriptions that included MEBO among the patients who received medications from the outpatient department in a public hospital in Alkharj.

Results: More than 61% of the patients who received MEBO ointment were female patients and about 61.98% of them received MEBO ointment for 1 week. Most of the prescribers were residents (76.86%). More than 46% of the prescriptions were prescribed by emergency department, about 24% were prescribed by plastic surgery department.

Conclusion: The use of MEBO ointment in the outpatient setting in Alkharj was uncommon. Further studies are needed to explore the pattern of using burn treating ointments such as MEBO ointment in the outpatient setting and in other settings.
Case Report on Guillain-Barre Syndrome (GBS) in Adult
Authors: Bende Pranay , Singh Seema
Published: January 2022

Introduction: Guillain-Barre-syndrome is when the immune system attacks the peripheral nervous system were disease progresses to trembling and muscle weakness in both hands and legs, which progress to upper body and arms.

Clinical Findings: High grade intermittent fever, low back pain, B/L LL weak, urinary incontinence which is intermittent in nature.

Diagnostic Evaluation: Neurological examination- revealed B/L UL and LL weakness, acute onset of quadriparesis. X-Ray – revealed normal sinus rhythm.  CSF examination – revealed No RBC; No pus cell; No Organism seen.

Lab investigation – Hb% 10%, total RBC count 4.45, total WBC 10400, total platelet 2.33, SGOT 226 SGPT 83, Peripheral Smear RBCs - Normocytic Normochromic platelets adequate smear no Haemoparasite seen. Blood Culture: revealed Growth of Acinetobacter species.

Therapeutic Intervention: Inj. Optineurone 1gm, Inj.Pantop 40mg, Tab.PCM,Inj. Tramadol 500mg, Immunoglobin (Ig) 100ml , physiotherapy and supportive therapy.

Outcome: The symptoms and clinical state of the patient improved over time. The patient's weakness began to improve after 5 days of IV-Ig therapy.

Conclusion: The patient was hospitalised to the neurosurgery ICU AVBRH on 05/06/20 with the known case of guillain-barre syndrome-(GBS). After receiving therapy, she showed significant progress.
A Review on Phytoconstituents of Brahmi and their Relation to Improve Nervous System
Authors: Heemanshi . , Sharma Reena
Published: January 2022

Ayurveda is a well-known practice for treating number of diseases from ages. It is a natural system from old age for the balancing of various body systems through herbs. There are lot of herbs used in curing the diseases and one among them is Brahmi. It has the ability to boost up the memory. Morphologically, it is a small sized succulent herb that have number of branches. This herb is well known for strengthening memory, brain functions and cooling properties. In this review paper, brief detail about its phytoconstituents and medicinal uses are discussed.
A Cross Section Study to Assess Factor Affecting the Work Life Balance of the Female Healthcare Professionals in the Private Hospitals of Vadodara – India
Authors: Parveen Khan Shabana , Chatterjee Subhasish , Wadhwa Medha
Published: January 2022

Purpose of the Research: work life balance is an important phenomenon concerning a lot of working employees. Females form a major proportion of the workforce in the healthcare industry and the policies should focus on their well being for a stress free environment. There has been a vast amount of research carried out focussing on this topic. However, there has been limited research concerning the work life balance of female healthcare professionals working in hospitals. Therefore, this study aims to assess the factor affecting the work life balance of the female healthcare professionals working in hospitals of Vadodara district (India).

Methodology: The data collection tool is a structured close ended questionnaire where in the respondents were asked to choose their option pertaining to various parameters of work life balance on a five point Likert scale. The collected from 335 female healthcare professionals working in seven private hospitals of Vadodara (India). The data collected were analyzed using SPSS version 23. The statistical test used was Kruskal-Wallis and Mann-Whitney test at 95% confidence level.

Major Results: There were 87 female doctors and 248 nurses in the study. Among the 335 respondents, 210 female healthcare professionals had 3-4 family size having the highest frequency, 297 female’s respondents were married, and 38 were single. The study showed that there was no difference in the work life balance of the females with respect to the family size because of cooking, child study, and other individual female’s responsibilities. Because of their marital status, there is a statistically significant difference in the work life balance of female healthcare professional.

Conclusions: For the employers the work life balance is an important human resource area of concern; hence, this study highlights an important issue to address for better satisfaction and content of the female healthcare professionals.
Etiology and Epidemiology of Maturity-onset Diabetes of the Young
Authors: Alghamdi Abdulwahid Mohammad , Alamer Zahra Yaser , Alamri Mohammed Abdulrahman , Alkorbi Ablaa Mubarak , Almtotah Abdullah Ghunaim , Alatawi Murtadha Ahmed , Abukhodair Areej Osama , Alassaf Mai Fahad , Alqahtani Shatha Ahmed , Asiri Ahmed Yahya , Abuaziz Roayad Mouayed , Alaama Jumana Osama
Published: January 2022

Evidence indicates that Maturity-onset diabetes of the young (MODY) exhibits an autosomal dominant inheritance and is the most common type of monogenic diabetes. However, it should be noted that misdiagnosis of the condition is very common, as patients are usually mistaken for both types I and type II diabetes mellitus. In the present study, we have discussed the etiology, pathogenesis, and epidemiology of MODY based on an extensive literature review. Genetic mutations are mainly attributed to the development of the disease, which usually manifests throughout the second to fifth decades of life. Pancreatic islet cell destruction, impaired insulin secretion, defects regarding threshold to serum glucose levels, and other pathological events are usually observed in these patients. Data regarding the epidemiology of the condition is not adequately reported in the literature, especially among non-European populations, indicating the need to conduct future investigations. Ethnic and age variations are potentially epidemiological characteristics of the disease. However, not enough data are present in the literature to support such conclusions.