bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcatheter aortic valve replacement and His bundle pacing in the presence of severe left ventricular dysfunction and left bundle branch block
Authors: São Thiago Luiz , Luciano Luis , Tscha Aline , Guimarães Artur , Silva Alice , Dal Forno Alexander
Published: June 2021

Aortic stenosis is the most prevalent valve disease in developed countries and has high morbidity and mortality after the onset of symptoms. The prevalence of severe aortic stenosis in elderly patients (>75 years) is approximately 3.4%. The transcatheter aortic valve replacement has been employed for approximately 20 years and had robust outcomes published. However, it is a challenging procedure when performed on a patient in cardiogenic shock, caused by severe deterioration of left ventricular function, a condition aggravated in cases of electromechanical dyssynchrony due to left bundle branch block. There is evidence that reestablishing the electrical conduction with a pacemaker implanted directly in the conduction system, in patients with left ventricular dysfunction and dyssynchrony, can significantly improve the systolic function. In this context, the objective of the present study was to present and discuss the particularities and evidence available for treating this complex subgroup of patients.
Peran Guru dalam Pengambangan Multimedia Interaktif (Suatu Tinjauan Kompetensi Guru dan Kaitannya dengan Media Interaktif)
Authors: Anasti Huriyah Padhilah
Published: June 2021

Media pembelajaran merupakan bagian terpenting dalam suatu proses pembelajaran. Media pembelajaran merupakan suatu alat yang digunakan untuk membantu proses belajar mengajar. Tujuan penggunaan media pembelajaran adalah untuk merangsang pola pembelajaran agar dapat mencapai keberhasilan pembelajaran dan mencapai tujuan yang diinginkan. Pengembangan dan pemanfaatan media pembelajaran berbasis multimedia interaktif tentunya tidak dapat dipisahkan dengan kompetensi yang dimiliki oleh guru. Hal ini mengingat bahwa guru berperan dalam segala bentuk proses pembelajaran.
Good Financial Grant Practice (GFGP): A Tool for Developing & Demonstrating Institutional Financial & Grant Management Capacity in Global Health
Authors: Harste Harry James , Kiff Genevieve , Okeke Iruka N. , Adebiyi Akindele O. , Ravikumar K. , Nagaraj Geetha , Ajiboye Jolaade J. , Castro Erik C. D. Osma , Herrera Elmer , Aanensen David M.
Published: June 2021

The administration and governance of grant funding across global health organizations presents enormous challenges. Meeting these challenges is crucial to ensuring that funds are used in the most effective way to improve health outcomes, in line with the United Nations' Sustainable Development Goal (SDG) 3, “Ensure healthy lives and promote well-being for all at all ages.” The Good Financial Grant Practice (GFGP) Standard (ARS 1651) is the world’s first – and currently only – international standard in the financial governance and management of grant funding. Through consensus building and global harmonization between both low and middle-income, and high-income country players, the GFGP Standard has achieved a levelling impact: GFGP applies equally to, and can be implemented by, all types of organization, regardless of location, size, or whether they predominantly give or receive funding. GFGP can be used as a tool for addressing some of the challenges of the current funding model. We describe our experiences and lessons learned from implementing GFGP across four diverse research institutions in India, Nigeria, Colombia, and the Philippines, as part of our UK National Institute for Health Research Global Health Research Unit (GHRU) on Genomic Surveillance of Antimicrobial Resistance.
LITERATURE READ WRITE AND RELATED WITH THE DEVELOPMENT OF INDONESIAN TEACHING MATERIALS
Authors: Kartika Putri
Published: June 2021

Reading and writing literacy is the knowledge and skills to read, write, search, search, process, and understand information to analyze, respond to, and use written texts to achieve the goal of developing understanding and potential. Reading and writing are very meaningful in science and knowledge, moreover the times have challenges, competition, and rapid technological movements, this greatly affects the world of education
Teacher Competencies and Their Relationship with Development of Interactive Media
Authors: Herman Hidayat
Published: June 2021

The essay aims to improve teacher competence.
Literature Read Write And Related With The Development Of Indonesian Teaching Materials
Authors: Asriati Dwi Putri
Published: June 2021

Literacy ability was originally defined as the ability to read and write, but now understanding has developed.
Nasionalisme dan Harapan Indonesia di Era Globalisasi yang PenuhTantangan
Authors: Samuel Kohl
Published: June 2021

Nationalism is a notion which argues that the loyalty of individuals should be left to the nation-state. Indonesian nationalism is the historical phenomenon that can not be removed from the influence of colonial powers of Western nations in the context of this colonial situation, the Indonesian nationalism is a response to the terms of political, socio-economic, cultural and specifically caused by the colonial situation. By kareka, then Indonesian nationalism in itself also contains three important aspects, namely political, economic social and cultural rights. From this statement it is understandable that if someone claimed a nationalist, then he must be willing to fight for the nation and state. This is condensed when the nation can traced Indonesia struggled to achieve independence, and maintaining independence.
The Role of Citizenship Education in Improving Pancasila Values in Millennial Generation
Authors: heriyanto yuki
Published: June 2021

There is an element that the millennial generation must maintain and apply Pancasila in real life. Through education, the millennial generation must be aware that Pancasila values such as divinity, humanity, unity, mutual cooperation, deliberation for consensus, social justice, patriotism, nationalism, and respect for differences are planted, not only for memorization, but more importantly for application to oneself and spreading to other millennial generations who both play an important role. Let us go with a torch that can spark the fire of enthusiasm to construct a victorious Indonesia for a better life in the future and throughout eternity. Using literature studies, this study will explain how citizenship education might increase a sense of Pancasila.
Konsep ekonomi masa Rasulullah SAW
Authors: Musdalifah
Published: June 2021

Artikel ini membahas tentang Konsep ekonomi masa Rasulullah SAW
Merkantilisme dalam perekonomian
Authors: Musdalifah
Published: June 2021

Artikel ini membahas tentang Merkantilisme dalam perekonomian
Tokoh merkantilisme
Authors: Muhib Muhammad
Published: June 2021

Konsep ekonomi merkantilisme muncul sekitar abad ke-18 dengan pandangan ekonomi yang berkaitan dengan konsep kesejahteraan negara. Konsep pemikirannya mengasumsikan bahwa suatu negara yang ingin lebih maju harus menjalin kerjasama perdagangan dengan negara lain, kemudian dari perdagangan luar negeri akan terjadi surplus perdagangan luar negeri berupa emas dan perak.
Artikel tentang Teori Ekonomi David Ricardo, Thomas Malthus dan Jean Baptistie Say
Authors: inayah Nurul
Published: June 2021

Artikel ini membahas tentang teori ekonomi david ricardo thomas maltus hean baptistie say
TWO LEGS POLICY (Indonesian Covid-19 Case Study)
Authors: naryono endang
Published: June 2021

The national covid-19 vaccination program carried out is still on a limited scale and is still below the target set by the government, especially compared to the population in Indonesia, this has resulted in the very highest Covid-19 growth rate, even the highest in Southeast Asia with one of the highest mortality ratios in the world in above 2.5%. The obstacle faced by the government is the limited number of vaccines imported from China, Europe and America, which incidentally are countries affected by COVID-19. then the uneven distribution of the covid-19 vaccine, this is due to the wide area of the country with uneven infrastructure facilities so that not all vaccinations can be carried out in sub-districts or out of town. This results in the low number of people being vaccinated and the last is the lack of socialization, education and training. distribution of information about the importance of being vaccinated against covid-19 so that many people refuse to be vaccinated, and do not understand the importance and benefits of having a vaccine for covid-19. This is a big gamble for Indonesia in dealing with COVID-19, which is getting more and more frightening with the discovery of a new variant resulting from a mutation that is much more deadly. This covid-19 vaccination is an absolute must and must be successful because if this fails it will result in a frightening humanitarian disaster, breaking the chain of distribution with strict rules and sanctions against the community in implementing the Health protocol must be carried out continuously and continuously
PERANCANGAN SISTEM INFORMASI MANAJEMEN STOK MAKANAN PADA RESTORAN BUBUR AYAM DOPLANGAN
Authors: Anggoro Dhanang Tias , Yunestri Rulin , Chaniago Shafirah Nurlita
Published: June 2021

Proses manajemen penjualan pada restoran Bubur Ayam Doplangan, pengendalian stok makanan masih bersifat manual, sehingga berdampak pada sering terjadinya ketidakakuratan dan keterlambatan proses pemesanan menu. Hal ini terjadi karena ketiadaan sebuah sistem berbasis komputer yang dapat memudahkan pelanggan dalam pemesanan menu, penghitungan jumlah pembayaran di bagian kasir, dan pihak manajemen mengalami kesulitan dalam pembuatan laporan penjualan yang menyulitkan pengambilan keputusan. Penelitian ini dibuat untuk merancang suatu sistem informasi manajemen stok berbasis client-server untuk memantau stok makanan pada restoran Bubur Ayam Doplangan dengan lebih mudah dan otomatis. Sistem pemesanan menu ini menggunakan aplikasi mobile pada sisi pelanggan dan aplikasi desktop pada bagian dapur. Metode pengembangan aplikasi yang digunakan adalah metode Rapid Application Development (RAD), dengan desain perangkat lunak berorientasi objek Unified Modeling Language (UML). Untuk menguji rancangan penelitian ini diasumsikan seorang pelanggan melakukan pemesanan ketika stok makanan di dapur akan habis. Hasilnya pada sistem yang terpasang pada bagian dapur akan memunculkan pesan pemberitahuan bahwa stok akan habis. Dengan demikian, bagian dapur dapat melakukan penambahan stok sehingga stok menu selalu tersedia dan tidak ada lagi pelanggan yang merasa kesal dan kecewa.
Sejarah Pemikiran Ekonomi Islam pada Masa Rasulullah SAW
Authors: Muhib Muhammad
Published: June 2021

Pemikiran ekonomi Islam muncul serentak dengan wahyu Al-Qur'an dan kehidupan Nabi pada akhir abad keenam hingga awal abad ketujuh. Penerapan sistem ekonomi Islam sudah ada dan Nabi Muhammad menjadikannya teladan bagi umat Islam. Bahkan orang Arab terkenal sebagai bangsa pedagang sebelum zaman Nabi Muhammad SAW
MAKALAH KELOMPOK 4 TEOLOGI PERJANJIAN BARU “YESUS DAN PENGGUNAAN RETORIKA DALAM ARGUMENTASI TEOLOGI”
Authors: Afni Jelsi
Published: June 2021

Kami sangat bersyukur atas berkat dan pertolongan Yesus Kristus dalam menuntun kami sehingga kelompok dapat menyelesaikan tugas makalah ini mengenai “YESUS DAN PENGGUNAAN RETORIKA DALAM ARGUMENTASI TEOLOGI”tepat pada waktunya. Adapun tujuan dari penulisan makalah ini untuk memenuhi tugas dari Dosen mata kuliah TEOLOGI PERJANJIAN BARU. Selain itu makalah ini juga bertujuan untuk menambah wawasan mengenai Yesus dan penggunaan retorika dalam argumentasi teologi bagi para pembaca dan juga bagi penulis.
Teacher Competencies and Their Relationship with Development of Interactive Media
Authors: Atrabu Westi Septia
Published: June 2021

This essai aims to improve teacher competence.
Teacher Competences and Its Relation to the Development of Interactive Media in Learning
Authors: Saputra Dedi
Published: June 2021

Teacher is a profession who to Educare children in one nation. That's mean responsibilities of teacher really important to approve skill of student at school. Teacher competences is a thing who must they have. They can development Interactive media for helping students to get the goal of learning at school.
Social and cultural determinants of help-seeking in Cuba and Germany – A structural equation model approach
Authors: Nohr Laura , Bürkner Paul - Christian , Ruiz Alexis Lorenzo , Ferrer Juan Emilio Sandoval , Capponi Davide , Buhlmann Ulrike
Published: June 2021

Social support is an important determinant of help-seeking in the context of mental health. Previous evidence shows differences in the relation between social support and help-seeking between more collectivistic vs. more individualistic cultures. Especially the cultural informed role of the family might play a key role in help-seeking decisions. Still, many studies have been conducted with minority groups in Western societies which have to face additional struggles due to immigration. The current study investigates help-seeking, social support, cultural values, and help-seeking intentions in the Cuban and German general populations. A cross-sectional questionnaire survey was applied to n = 340 Cuban and n = 340 German adults. Multiple-group structural equation modeling was used to examine measurement invariance between the groups and to explore relationships between the concepts under study in both cultural groups. No measurement invariance could be established for the overall model and most of the measures separately which impedes cross-cultural comparisons. Using plausible values, the structural model was estimated in both samples separately. Not all hypotheses could be supported for the Cuban and German samples. Yet, social support and the importance of family predicted informal and formal help-seeking significantly but differently in both samples. In the light of methodological limitations, their potential to support or to prevent different forms of help-seeking are discussed and possible practical implications derived.
Temporal integration for amplitude modulation in childhood: Interaction between internal noise and memory factors
Authors: Cabrera Laurianne , Lorenzini Irene , Rosen Stuart , varnet léo , Christian Lorenzi
Published: June 2021

It is still unclear whether the gradual improvement in amplitude-modulation (AM) sensitivity typically found in children up to 10 years of age reflects an improvement in “processing efficiency” (the central ability to use information extracted by sensory mechanisms). This hypothesis was tested by evaluating temporal integration for AM, a capacity relying on memory and decision factors. This was achieved by measuring the effect of increasing the number of AM cycles (2 vs 8) on AM-detection thresholds for three groups of children aged from 5 to 11 years and a group of young adults. AM- detection thresholds were measured using a forced-choice procedure and sinusoidal AM (4 or 32 Hz rate) applied to a 1024-Hz pure-tone carrier. All age groups demonstrated temporal integration for AM at both rates, that is significant improvements in AM sensitivity with a higher number of AM cycles. However, both 5- 6 years and adults exhibited similar levels of temporal integration, while 7-8 and 10- 11 years showed less integration. This is because at both rates: (i) the youngest group (5-6 years) displayed the worst thresholds with 2 AM cycles but similar thresholds with 8 cycles compared to older children groups, and (ii) adults showed the best thresholds with 8 AM cycles but similar thresholds with 2 cycles compared to older children groups. Computational modelling indicated that higher levels of internal noise combined with poorer short-term memory capacities in children accounted for the developmental trends. Improvement in processing efficiency may therefore account for the development of AM detection in childhood.
Is Earth a Perfect Square? Repetition Increases the Perceived Truth of Highly Implausible Statements
Authors: Lacassagne Doris , Béna Jérémy , Corneille Olivier
Published: June 2021

A single exposure to statements is typically enough to increase their perceived truth. This Truth-by-Repetition (TBR) effect has long been assumed to occur only with statements whose truth value is unknown to participants. Contrary to this hypothesis, recent research found a TBR effect with statements known to be false. Of note, a recent model even posits that repetition could increase the perceived truth of highly implausible statements. As for now, however, no empirical evidence has reported a TBR effect for highly implausible statements. Here, we reasoned that one may be found provided a sensitive truth measure is used and statements are repeated more than just once. In a preregistered experiment, participants judged the truth of highly implausible statements on a 100-point scale, and these statements were either new to them or had been presented five times before the judgment task. We observed a TBR effect: truth judgments were higher for repeated statements than for new ones - even if all statements were still judged as false. Exploratory analyses additionally suggest that all participants were not equally prone to this TBR effect: about half the participants showed no or even a reverse effect. Overall, the results provide direct empirical evidence to the claim that repetition can increase perceived truth even for highly implausible statements, although not equally so for all participants and not to the point of making the statements look true.
Caregiving in Times of Uncertainty: Helping Adult Children of Aging Parents Find Support during the COVID-19 Outbreak
Authors: Lightfoot Elizabeth , Moone Rajean P.
Published: June 2021

The COVID-19 pandemic, which is especially dangerous to older people, has disrupted the lives of older people and their family caregivers. This commentary outlines the adaptive and emerging practices in formal supportive services for family caregivers, the changing types of support that family caregivers are providing to their older relatives, and the ways family caregivers are seeking informal caregiving support during the COVID-19 outbreak.
MANAJEMEN PELAYANAN KEPERAWATAN BEDAH DI RUMAH SAKIT
Authors: Harniati  , Risnawati
Published: June 2021

Dalam buku ini akan dibahas tentang Konsep Manajemen, Fumgsi dan proses serta analisis manajemen serta bagaimana Proses Manajemen Pelayanan Keperawatan Bedah di Salah satu Rumah Sakit dan semoga buku ini bisa menjadi Referensi bacaan bagi Mahasiwa Keperawatan ataupun Akademisi (Dosen) dalam menambah pengetahuan Manajemen Pelayanan Keperawatan Bedah.
„Po prostu pracowałam”. Z Jolantą Wadowską-Król rozmawia Lucyna Sadzikowska
Authors: Wadowska-Król Jolanta , Sadzikowska Lucyna
Published: June 2021

Publikacja z okazji nadania Pani Jolancie Wadowskiej-Król godności Doktora Honoris Causa Uniwersytetu Śląskiego w Katowicach.
Ołów w środowisku
Authors: Cabała Jerzy , Janeczek Janusz , Kowalczyk Andrzej
Published: June 2021

W publikacji zostały opisane zagadnienia związane z naturalnym występowaniem ołowiu w środowisku oraz jego wtórnymi, antropogenicznymi koncentracjami w glebach, wodach i pyłach atmosferycznych. Przedstawiono zmieniające się kierunki wykorzystania ołowiu w okresie ostatnich kilku tysięcy lat. Zwrócono uwagę, że stosunkowo niskie temperatury hutniczej produkcji oraz korzystne właściwości sprzyjały masowemu wykorzystaniu ołowiu, jednego z siedmiu najwcześniej poznanych metali. Wskazano, że jedną z przyczyn szybko rosnącego wydobycia ołowiu było pozyskiwanie srebra ze złóż galeny. Omówiono geochemię i mineralogię ołowiu w kontekście koncentracji oraz form występowania tego pierwiastka w różnych środowiskach litosfery. Silna skłonność ołowiu do wiązania się z siarką powoduje, że najczęściej występuje w siarczku Pb, galenie. W etapie utlenienia powstaje węglan Pb, cerusyt, znacznie rzadziej, w obecności jonów innych pierwiastków, np.: P, As, Mo, V, Cr tworzy fosforany, arseniany, molibdeniany, wanadyniany i chromiany ołowiu. Scharakteryzowano geologię oraz zespół minerałów występujących w śląsko-krakowskich złożach rud Zn-Pb. Stosunkowa niska aktywność geochemiczna jonów ołowiu Pb2+ powoduje, że w warunkach naturalnych transfer ołowiu do organizmów żywych jest ograniczony, jednak znacząco rośnie dla syntetycznych minerałów lub związków ołowiu.Opisano metody przeróbki rud Zn-Pb oraz hutniczej produkcji ołowiu, która od XIX wieku była związana z szybko rosnącą produkcją cynku, dlatego jednym ze znaczących źródeł emisji ołowiu są huty cynku. Wskazano na znaczącą rolę regionu śląsko-krakowskiego dla globalnej produkcji ołowiu, cynku i kadmu w okresie XIX i na początku XX wieku. Przedstawiono wielkość produkcji ołowiu na świecie i w Polsce. W kontekście rożnych zastosowań ołowiu (akumulatory, stopy, farby, dodatek czteroetylku Pb do benzyn itp.) wskazano na najważniejsze źródła emisji ołowiu i jego związków do gleb, wód i atmosfery. Zestawiono źródła i wielkośćemisji Pb w Europie w latach 1955–2010. Bardziej szczegółowe informacje dotyczące emisji ołowiu do środowiska odnoszą się do regionu śląsko-krakowskiego, gdzie od ponad 200 lat liczne huty produkowały ołów, cynk oraz stopy metali nieżelaznych, co wiązało się z lokalnym i regionalnym zanieczyszczeniem środowiska metalami ciężkimi. Szczególnie silne, toksyczne oddziaływania na organizmy żywe wywiera ołów, szczególnie jego syntetyczne formy emitowane przez huty oraz zakłady wykorzystujące ten metal. Okresy największej prosperity śląskiego hutnictwa ołowiu, cynku i kadmu wiązały się ze wzrostem zatrudnienia, z rozwojem gospodarczym i ogromnymi zyskami dla właścicieli. Z drugiej strony przyczyniły się do katastrofalnego zanieczyszczenia środowiska oraz trudnej do oszacowania skali zachorowań dzieci i dorosłych w wyniku zatrucia ołowiem.
Transformation of the Global Film Industry: Prospects for Asian Countries
Authors: Paksiutov Georgii D.
Published: June 2021

The current rapid development of some Asian economies and the projected economic dominance of Asia in the 21st century are reasons enough to call it “the Asian century.” But will Asia’s economic growth entail an increase in political power and cultural influence? In this article the author looks at the topic through the lens of the film industry, a field of activity with a plethora of intertwined economic, political, and cultural factors. Cinema is studied here as an industry that produces “meanings” and is coupled with the concept of “strategic narratives.” According to some statistics, Asian cinema is becoming increasingly important in terms of the size of national film markets, but for a variety of reasons the U.S. remains the world’s most important exporter of motion pictures. The position of Asian countries in world cinematography is undermined by such global institutions as award ceremonies and film festivals that are held in the U.S. and Europe and tend to favor Western filmmakers. This article emphasizes the dramatic influence of digital transformation on modern cinematography and the opportunities it opens up for Asian film producers in creating a new, global streaming services market. Finally, the paper discusses development prospects for the film industries in four Asian leaders in this field—China, Japan, South Korea, and India. Japan and South Korea are likely to increase their cooperation with the U.S. in cinematography. There are great opportunities for cooperation between the film industries of India and China, but they are heavily dependent on political relations between the two nations. China’s film industry is expected to continue to develop rapidly.
Offending with Fascism, Or More on the Relevance of History
Authors: Solovyov Sergei M.
Published: June 2021

Marlene Laruelle’s article in Russia in Global Affairs (Laruelle, 2020) addresses current political debate on Russia’s role in the world political system. However, it is of much greater interest not to argue whether modern Russia can be called “fascist” or if such a discussion can take place at all (in fact, it most certainly can, for it is already in progress: invectives of this sort are voiced both inside and outside Russia), but to talk about the theoretical—or pseudo-theoretical—basis of such debates.
Pemberian Wasiat Wajibah kepada Istri Non Muslim Menurut Putusan Mahkamah Agung RI NO. 16K/AG/2010
Authors: Ismail Abdul Hadi
Published: June 2021

Beragamnya agama yang ada di Indonesia, menyebabkan perkawinan beda agama rentan terjadi. Perkawinan beda agama akan berimplikasi kepada adanya kewarisan beda agama jika salah satu pasangan meninggal dunia, sehingga akhirnya akan menjadi sengketa waris. Para ulama fikih telah sepakat bahwa antara muslim dengan non muslim tidak saling mewaris, meskipun sebagian ulama membolehkan terjadinya peralihan harta melalui wasiat wajibah. Secara normatif tidak ada hukum positif yang mendasari pemberian wasiat wajibah kepada istri yang tidak beragama Islam. Kompilasi Hukum Islam hanya mengatur wasiat wajibah kepada anak angkat atau orang tua angkat.  Kekosongan hukum tersebut kemudian mendorong Mahkamah Agung Republik Indonesia memberikan putusan untuk memberikan bagian harta dari suami/istri non muslim melalui mekanisme wasiat wajibah. Berdasarkan konsideran tersebut, maka perlu dipertanyakan bagaimana wasiat wajibah terhadap non muslim dalam perspektif KHI, serta apa yang menjadi dasar Putusan Mahkamah Agung RI memutuskan pemberian wasiat wajibah kepada istri non muslim. Penelitian ini adalah penelitian hukum normatif dengan sumber data berasal dari data sekunder. Hasil penelitian ini adalah bahwa pertimbangan yang menjadi dasar terbitnya Putusan Nomor 16 AK/G/2010 itu adalah rasa keadilan serya kemanusiaan, disebabkan istri telah mengabdikan dirinya selama 18 tahun dan bergaul dengan suami secara rukun dan baik.
State border fences as a threat to habitat connectivity
Authors: Safner Toni , Šprem Nikica , Apollonio Marko , Flajšman Katarina , Pokorny Boštjan , Gligora Ivan , Gracanin Ana
Published: June 2021

The conservation value of transboundary management of wildlife populations in Europe, that marked end of the 20th and the beginning of the 21th century, has come under huge pressure since 2015 especially in the South-eastern ­Europe due to border fences construction in response to large influxes of refugees/migrants. The primary aim of this study was to present data on the direct impacts of the long fence on wildlife (e.g. fence-related mortality) across the Hungary–Croatia border. We collected data on fence-related animal mortality along 136 km of the fence in the first 28 months after its construction. In total, 64 ungulates (38 red deer, 23 roe deer, and three wild boar) were found ­entangled in or deceased due to the razor wire fence. In addition, we present direct (photographic) evidence of newly recorded behaviour of red deer, as they gather in huge herds attempting to cross the border fence between Hungary and Croatia. Short term effect of the border fence is reflected in direct animal mortality, and as obstruction to the movement and behaviour of animals. In the case that current fences will remain or continue to expand along the northern boundary of South-eastern Europe, it is likely that fragmented wildlife populations in the region will suffer from negative effects of genetic subdivision such as loss of alleles and reduced heterozygosity that can cause important long-term damage to their vitality.
Liberalism, Social Democracy, and Tom Kent
Authors: Dewar Kenneth C.
Published: June 2021

This article argues that the lines separating different modes of thought on the centre-left of the political spectrum—liberalism, social democracy, and socialism, broadly speaking—are permeable, and that they share many features in common. The example of Tom Kent illustrates the argument. A leading adviser to Lester B. Pearson and the Liberal Party from the late 1950s to the early 1970s, Kent argued for expanding social security in a way that had a number of affinities with social democracy. In his paper for the Study Conference on National Problems in 1960, where he set out his philosophy of social security, and in his actions as an adviser to the Pearson government, he supported social assistance, universal contributory pensions, and national, comprehensive medical insurance. In close association with his philosophy, he also believed that political parties were instruments of policy-making.
Налоги и налогообложение. Учебно–методическое пособие. Для студентов ВУЗов. Издание, исправленное и дополненное / Автор–составитель И. В. Чурзина – М.: «КДУ», «Университетская книга». – 2021. – 282 с.
Authors: Чурзина И. В.
Published: June 2021

Пособие содержит необходимый комплекс учебных и методических материалов, позволяющих освоить курс «Налоги и налогообложение». В состав пособия входят: учебная программа, краткое изложение тем, перечень ре- комендуемой литературы, словарь терминов (глоссарий), вопросы к экзамену (зачету). В исправленном и дополненном издании учтены все изменения в налоговом законодательстве 2021 года. К каждой теме разработан комплекс методических материалов (вопросы для обсуждения, проблемные вопросы и ситуации, задачи, тесты) для углубления и лучшего усвоения знаний по предмету. Рекомендуется для студентов экономических и управленческих специальностей. Может быть использовано для самостоятельного или дистанционного изучения дисциплины «Налоги и налогообложение».
A morte midiatizada de Júpiter Maçã: performance e tradições funerárias
Authors: Govari Caroline
Published: June 2021

Este artigo pretende discutir a midiatização da morte de Júpiter Maçã, pensando seu funeral como uma performance teatral e analisando a influência da mídia na mitificação do artista. Trabalhamos com conceitos dos Estudos de Comunicação para discutir os processos midiáticos e conceitos dos estudos de Performance para discutir o evento fúnebre em si. Autores como Gomes (2013), Hjavard (2012), Turner (1982), Schechner (2006) e Taylor (2013) são alguns dos que nos oferecem suporte para esta análise.
VENTILATORY AND METABOLIC RESPONSES DURING FIELD TESTS AND CPX IN OBESE ADULTS
Authors: Oliver Nicole , Carlos Renata , Onofre Tatiana , De Sá Joceline Cássia Ferezini , Da Silva Eliane Pereira , Bruno Selma
Published: June 2021

The 6 minute walk test (6MWT) and the incremental shuttle walking test (ISWT) have been used as an alternative to the Cardiopulmonary Exercise Test (CPX) for functional evaluation as well after rehabilitation programs. The objective was to analysis the cardiorespiratory and metabolic demands among the ISWT, 6MWT and CPX in the obese and the contribution of adiposity markers on this response. An observational and cross-sectional study was conducted with fifteen obese (10 women; 39.4+10.1years), performing CPX, 6MWT and ISWT. The subjects were as initial part of a rehabilitation program and bariatric surgery at the University Hospital. Metabolic and ventilatory variables were recorded by a telemetry system during all tests. Peak oxygen uptake-VO2peak was similar between CPX (18.6±4.0ml/kg/min) and ISWT (15.4±2.9ml/kg/min) and different from 6MWT (13.2±2.5ml/kg/min). There was agreement (3.2ml/kg/min; 95%; IC-3.0-9.4) between VO2peak of CPX and ISWT. CPX duration (R2=0.61;p=0.001) was best-fit by waist circumference (WC) and the body adiposity index(BAI) that reduced 4.7% and 3.2% CPX duration respectively. Forced vital capacity-FVC and WC predicts increasing of carbon dioxide production (VCO2) on CPX (R2=0.95;p=0.001) and ISWT (R2=0.67;p=0.001). In conclusion the obese individuals perform the ISWT and CPX test with similar physiological responses. It is suggested that, ISWT could be an alternative to CPX and that metabolic monitoring of ISWT by telemetry can be useful for the clinical assessment of the functional capacity of the obese.
Effect of Solitary on Depression and Well-being of Older Adults Residing in Old Homes
Authors: Sattar Ammara , Riaz Muhammad Naveed , Rashid Asma
Published: June 2021

The study aimed to examine the effect of solitary on depression and the well-being of older adults residing in old homes. The sample comprised of older adults residing in old homes (N = 100). Solitude Scale, Depression subscale of Depression, Anxiety, and Stress Scale and Short Warwick Edinburg Mental Well-Being Scale were applied on the older adults. Linear Regression analysis showed that solitary positively predicted depression in older adults residing in old homes, whereas solitary negatively predicted well-being in older adults residing in old homes. The findings of this study can be used to improve the mental health of older adults residing in old homes.
An Analysis of Risk Factors Associated with Methamphetamine/ICE use in Khyber Pakhtunkhwa, Pakistan
Authors: Jan Sameer Ul Khaliq , Alam Hamid , Khan Ayub
Published: June 2021

The present study aims to analyze the causative factors which are responsible for the use of a stimulant drug methamphetamine which is commonly known as ice. For this purpose, data were collected from the two districts, i.e. Peshawar and Mardan, Khyber Pakhtunkhwa, Pakistan. A conceptual framework consists of Independent variable (ice use frequency) and dependent variables (risk factors). Data was collected through a structured questionnaire from a sample of 180 ice users by a snowball sampling technique. A Chi-square test was applied to examine the association between independent and dependent variables. The results reveal that a significant (p=0.05) association was found between various risk factors, i.e. easy availability, friends insistence, try out new experiences/curiosity, and use of ice for exam preparation with frequent use of ice. The study recommends that awareness may be created through educational, religious institution and media for the prevention and rehabilitation of ice addiction.
COMPONENT COMPOSITION AND ANTIOXIDANT POTENTIAL OF CYSTOSEIRA BARBATA FROM THE BLACK SEA
Authors: MANEV Zdravko Kr. , PETKOVA Nadezhda Tr.
Published: June 2021

The purpose of this study was to analyze some chemical elements and to determine the content of total phenols and pigments in the brown seaweed Cystoseira barbata from Rusalka Cape near the Black Sea. In addition, the antioxidant potential of this algae was also evaluated by four methods based on different mechanisms. The obtained results were compared with other scientific studies related to inorganic and organized compositions of Cystoseira barbata from different marine regions.It was found that the seaweed from Rusalka Cape contained high values of manganese, chromium and boron and a high concentration of carotenoids. Therefore, this seaweed was evaluated as a source of microelements, carotenoids and antioxidants.
DRYING CHARACTERISTICS OF ONION PROCESSING WASTE
Authors: PROKOPOV Tsvetko , GEORGIEVA Maryia , NIKOLOVA Milena , ATANASOV Dimitar , TANEVA Donka
Published: June 2021

Onion processing waste (OPW) was dried in a convective hot-air laboratory scale dryer at 50, 60, 70 and 80ºC. The effect of drying temperature on the drying characteristics and on the total phenolic and total flavonoid content of dried samples was determined. Three mostly used models were applied for fitting the experimental drying curves. The results indicated that the constant rate-drying period was not observed and that the logarithmic model was the most suitable for fitting the experimental drying kinetic data. The drying temperature significantly affected the total phenolic and total flavonoid content of dried OPW. The values of effective diffusivity were calculated and the determined value of activation energy was 28.05 kJ/mol.
Influence of size effects and granule distribution by size on optical and magneto-optical properties of nanocomposites
Authors: Yurasov A. N. , Yashin M. M. , Gladyshev I. V. , Semyonova D. V. , Gan’shina E. A. , Kanazakova E. S.
Published: June 2021

In this paper, the spectral dependences of the transverse Kerr effect (ТКЕ) are studied experimentally and theoretically. The results are obtained for deposited and annealed samples with a corresponding variation in the size of the granules. It was found that thermomagnetic annealing leads to an increase in the ТКЕ value in magnetic nanostructures, while the most noticeable changes in the effect value were observed in the range of medium and high concentrations of the magnetic component in the visible region of the spectrum. The expediency of using the effective medium approach for calculating magneto-optical effects in granular systems, taking into account the size distribution of granules within the lognormal distribution of granules, is shown. Based on this approach, the main features of the optical and magneto-optical properties of nanocomposites are explained by the example of (Co45Fe45Zr10)X(Al2O3)1–X. All calculations are performed in the Bruggemann approximation, which effectively describes the properties of nanostructures in the region of average concentrations. Size effects are clearly manifested in nanocomposites and have a significant impact on the optical and magneto-optical properties of nanocomposites, especially in the IR region of the spectrum, which is associated with intraband transitions. Taking into account the particle size distribution makes it possible to significantly improve the description of such promising inhomogeneous nanostructures. The solved problem is very important and relevant both from the fundamental point of view – the study of magneto-optical, optical and transport phenomena in nanocomposites – and from the point of view of the great possibilities of their application in modern electronics and nanoelectronics. Taking into account the size effects and the particle size dispersion makes it possible to find new promising functional materials and control their properties in a wide spectral range.
Data analysis methods in astronomic objects classification (Sloan Digital Sky Survey DR14)
Authors: Golov V. A. , Petrusevich D. A.
Published: June 2021

In the paper Sloan Digital Sky Survey DR14 dataset was investigated. It contains statistical information about many astronomical objects. The information was obtained within the framework of the Sloan Digital Sky Survey project. There are telescopes at the Earth surface, at the Earth orbit and in the Lagrange points of some systems (Earth–Moon, Sun–Earth). The telescopes gain information in different frequency ranges. The large quantity of statistical information leads to the demand for analytical algorithms and systems capable of making classification. Such information is marked up well enough to build machine learning classification systems. The paper presents the results of a number of classifiers. The handled data contains measures of three types of astronomical objects of the Sloan Digital Sky Survey DR14 dataset (star, quasar, galaxy). The CART decision tree, logistic regression, naïve Bayes classifiers and ensembles of classifiers (random forest, gradient boosting) were implemented. Conclusions about special features of each machine learning classifier trained to solve this task are made at the end of the paper. In some cases, classifiers’ structure can be explained physically. The accuracy of the classifiers built in this research is more than 90% (metrics F1, precision and recall are implemented, because the classes are unbalanced). Taking these values into account classification task is supposed to be successfully solved. At the same time, the structure of classifiers and importance of features can be used as a physical explanation of the solution.
METHODOLOGICAL PROJECTS FOR ORGANIZING SEMANTIC READING OF AN INFORMATICS TEXTBOOK
Authors: Malova I. Е. , Timohina A. S.
Published: June 2021

The purpose of the research presented in the article was to identify the problems of organizing semantic reading by future informatics teachers and to determine ways to solve these problems. The research methodology provided for the following stages: 1) the formulation of a task for students  — future informatics teachers  — to create a methodological project for organizing the semantic reading of an informatics textbook and providing examples of projects completed by other students; 2) students' performance of the assignment using a computer presentation, on the slides of which a fragment of the text of the textbook is presented and with the help of which a dialogue with the students is carried out; 3) analysis and correction, if necessary, of the methodological actions of the authors of the projects; 4) generalization of the encountered problems and ways to overcome them. Students are given the opportunity at any stage to get acquainted with the projects carried out by other students. As a result, it was confirmed the effectiveness of the selection of objects of semantic reading and the use of the method "Make up questions to which there are answers in the text", additional questions, the "curtain" method; the difficulties of students in organizing the semantic reading of solving problems were determined; a technique has been developed to overcome these difficulties. The value of the research lies in improving the methodological experience of the participants in experimental work, in the possibility of transferring the technology of methodological projects for organizing semantic reading to other topics of informatics, to other academic subjects, in the possibility of using the developed methodological projects in practice both at school when teaching students and at university when working with future informatics teachers.
USING VIRTUAL WORLDS TO DEVELOP THINKING IN PRESCHOOL CHILDREN
Authors: Filipov A. V.
Published: June 2021

During the first seven years of his life, the child receives a huge amount of knowledge about the world around him. The development of the child's thinking during this period and the results of his knowledge of the world around him affect the further educational activities of the preschooler. Thanks to the development of thinking, a child is able to imagine an image of an object and its properties in the absence of the object itself, based only on previously received information. In a child in the early and preschool years of life, game is the main activity for forming a personality. Didactic games facilitate the process of all-round development of children. Various tasks solved in didactic games are presented for children in an interesting and attractive form of activity. In a computer game, using simulation, it becomes possible to demonstrate objects and phenomena that are inaccessible to a child in the real world. The use of didactic computer games not only increases the preschooler's motivation to learn new material, but also contributes to the development of thinking. An educational computer game acts as a mentor for a child. However, the lack of communication with a living, and not virtual, mentor causes a negative effect both on the development of the child's speech and the formation of his communicative abilities. Therefore, a computer game cannot be perceived as a complete alternative to the classical means of teaching and educating preschoolers.
Minocycline Improves Memory by Enhancing Hippocampal Synaptic Plasticity and Restoring Antioxidant Enzyme Activity in a Rat Model of Cerebral Ischemia-Reperfusion
Authors:   Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Parvardeh Siavash , Sheikholeslami Mohammad Abbas ,   Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Ghafghazi Shiva ,   Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Pouriran Ramin ,   Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mortazavi Seyed Erfan ,   Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Published: June 2021

Introduction: Oxidative stress plays a crucial role in the impairment of synaptic plasticity following cerebral ischemia, ultimately resulting in memory dysfunction. Hence, the applying antioxidant agents could be beneficial in managing memory deficits after brain ischemia. Minocycline is a tetracycline antibiotic with antioxidant effect. The main objective of this work was to assess the minocycline effect on the impairment of synaptic plasticity and memory after cerebral ischemia-reperfusion in rats. Methods: Transient occlusion of common carotid arteries was used to induce ischemia-reperfusion injury in rats. Single or multiple (once daily for 7 days) dose(s) of minocycline were administered before (pretreatment) or after (treatment) brain ischemia. Seven days after ischemia-reperfusion, passive avoidance performance, long-term hippocampal potentiation, and the activity of antioxidant enzymes were assessed. Results: The passive avoidance test showed that minocycline (20 and 40 mg/kg) significantly increased step-through latency while reducing the duration of staying in a dark chamber in the treatment (but not pretreatment) group. In electrophysiological experiments, the rats treated (but not pretreated) with minocycline (40 mg/kg) showed a significant increase in the amplitude of the field excitatory postsynaptic potentials in the dentate gyrus area of the hippocampus. The treatment (but not pretreatment) with minocycline (20 and 40 mg/kg) resulted in a significant increase in the activity of catalase, glutathione peroxidase, and superoxide dismutase in the hippocampus. Conclusion: It was determined that minocycline attenuates memory dysfunction after cerebral ischemia-reperfusion in rats by improving hippocampal synaptic plasticity and restoring antioxidant enzyme activity.
Reprogramming by Cytosolic Extract of Human Embryonic Stem Cells to Improve Dopaminergic Differentiation Potential of Human Adipose Tissue-derived Stem Cells
Authors:   Department of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran., Mobasseri Sehar , Javeri Arash ,   Department of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran., Fakhr Taha Masoumeh ,   Department of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Published: June 2021

Introduction: The extract of pluripotent stem cells induces dedifferentiation of somatic cells with restricted plasticity. Methods: In this study, we used the extract of human embryonic stem cells (hESC) to dedifferentiate adipose tissue-derived stem cells (ADSCs) and examined the impact of this reprogramming event on the dopaminergic differentiation of the cells. For this purpose, cytoplasmic extract of ESCs was prepared by repeated freezing and thawing cycles. The plasma membrane of hADSCs was reversibly permeabilized by streptolysin O (SLO), exposed to hESC extract, and resealed by a CaCl2-containing medium. Results: As revealed by qPCR analysis, expression of OCT4, SOX2, NANOG, LIN28A, and KLF4 mRNAs were downregulated in the ADSCs one week after extract incubation, while all mRNAs except for KLF4 were upregulated at the end of the second week. For dopaminergic differentiation, control and reprogrammed ADSCs were induced by a serum-free neurobasal medium containing B27 and a cocktail of sonic hedgehog (SHH), basic fibroblast growth factor (bFGF), fibroblastic growth factor 8 (FGF8), and brain-derived neurotrophic factor (BDNF) for 12 days. After differentiation, the expression levels of some neuronal and dopaminergic-related genes, including PAX6, NESTIN, NEFL, GLI1, LMXB1, EN1, NURR1, and TH, significantly increased in the reprogrammed ADSCs compared to the control group. On the whole, two weeks after reprogramming by ESC extract, ADSCs showed an improved dopaminergic differentiation potential. Conclusion: These findings suggest that the cytoplasmic extract of hESCs contains some regulatory factors which induce the expression of pluripotency-associated markers in somatic cells and that the exposure to ESC extract may serve as a simple and rapid strategy to enhance the plasticity of somatic stem cells for cell replacement therapy purposes.