bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating the Mitigation Effect of Spirulina Against Radiation-Induced
Heart Injury
Authors: Nikzad Safoora , Ahmadvand Mohammad Hootan , Hashemi Sayed Payam , khoshghadam Alireza , Kalhori Fereshte , Mirzaei Fatemeh
Published: October 2022

Background:

During a radiological or nuclear disaster, exposure to a high dose of ionizing radiation usually results in cardiovascular diseases such as heart failure, attack, and ischemia.

Objective:

the purpose of this study was to examine mitigation effects of Spirulina in comparison to Metformin's.

Materials and Methods:

25 male Wistar rats were randomly assigned to five groups (5 rats in each): for the control group, rats did not receive any intervention. In group 2, spirulina was administered orally to rats. In group 3, rats were irradiated to the chest region with 15 Gray(Gy) x-radiation. In groups 4 and 5, The rats were irradiated in the same way as group 3. Forty-eight hours after irradiation, treatment with Spirulina and Metformin began. All rats were sacrificed after ten weeks and their heart tissues were removed for histopathological, and biochemical assays.

Results:

Results showed an elevation in Malondialdehyde (MDA) and decreasing superoxide dismutase (SOD) activity. Moreover, pathological changes of radiation were irregularities in the arrangement of myofibrils, proliferation, migration of mononuclear cells, vacuolation of the cytoplasm, and congestion. Administration of spirulina enhance the SOD activity while did not affect MDA level and pathological change in heart tissue. Despite spirulina, metformin had a considerable effect on pathological lesions and decrease the level of MDA.

Conclusion:

reactive oxygen species (ROS) may be involved in the late effects of radiation-induced heart injury and scavenging these particles may contribute to reduced radiation side effects. Based on these results, Spirulina had no effect on radiation-induced cardiac damage, while metformin did. Higher Spirulina doses given over a longer period of time will likely have a greater heart-mitigate effect.
Anti-Inflammatory Therapeutics: Conventional Concepts and Future with
Nanotechnology
Authors: Kaur Pawan , Bernela Manju , Kaushal Priya , Verma Naveen , Thakur Rajesh , Ahuja Munish
Published: October 2022

Anti-inflammatory therapies currently in use mainly include steroidal and non-steroidal
drugs. Contrary to their side effects, the steroid hormones glucocorticoids, which are synthetic
versions of natural cortisol, are nevertheless often employed to treat a variety of inflammatory
disorders. Other drug class of choice is non-steroidal drugs which mainly target COX-2 and hence
the synthesis of prostaglandins, particularly PGE2. To cure both the short-term effects of chronic
inflammatory disorders and the long-term symptoms of acute inflammation, pharmaceutical
chemists are in continuous search for more potent and less toxic agents. Apart from these two
drug classes, phytochemicals are gaining the attention of researchers as source of alternative antiinflammatory
agents. However, every drug class has its own advantages or disadvantages thus
requiring intervention of newer approaches. Currently, drugs used for anti-inflammatory therapies
are costly with low efficacy, high health risk, and socio-economic impact due to the concern issue
of their toxicity. Recently, nano-drug delivery system has been experiencing main interest as a
new approach for targeting therapeutic agents to the target sites in a controlled, sustained manner
and has various advantages as compared to the conventional drug delivery system like, increased
solubility, bioavailability, improved pharmacokinetic profile of drugs, surface area and rate of
dissolution and additionally, overcomes the problems related to hydrophobicity, toxicity. Present
review summarized the intervention of nanotechnology to overcome the limitations/ risk associated
with current anti-inflammatory drugs of different classes.
Devemos apelidá-los de estudos cine-culturais? O cine-mundificar da música popular e dos estudos juvenis
Authors: MacDonald Michael , Lima João
Published: October 2022

This article explorescinematic research-creation, or what I call cine-worlding. Indeed, ccine-worlding has the potential to contribute to a research practice unique to popular music and youth studies, areas of cultural life characterised by their openness and innovation with new media. Being aware of these opportunities means taking advantage of the technologies currently available. But there is an obstacle. Cinematic production must come together with research. Traditional cinematic research methods, due to their costs, difficulties with peer review and lack of institutional support, have not been accepted by academia. It has been anthropology that has done the most to develop cinematic research through ethnographic film. New developments in the digital cinema ecosystem have been little explored so far. The digital cinema ecosystem, emerging since 2009, consists of relatively cheap digital cameras and smartphones, free professional-grade digital platforms, a worldwide network of film festivals and the transformation of most art-house cinemas into digital screenings. This means that digital cinema made on a laptop can be shown anywhere. We are at the best possible moment for academic filmmaking, but then why do academics do so little of it?
K-pop. Os reflexos do hibridismo cultural na identidade e na música popular coreana
Authors: Milani Camila Alonso
Published: October 2022

This article seeks to analyze how K-pop, (sub) musical genre born in South Korea, is able to portray reflexes of cultural hybridism in pop music and in South Korean identity. To this end, a survey of facts and historical data was carried out to demonstrate the cultural identity suppression suffered by the Korean people over the centuries, until its consolidation as an independent nation. Then, from the post-war context, an analysis is made of the North American influence on the country's trajectory in music and in the construction of its pop culture. Finally, the role of all these interferences in the solidification of the South Korean identity is investigated, as well as the role of globalization in the establishment of the K-popper subculture and the new position of the peninsular country in the world
Priority Mapping for Handling Environmental Road Using GIS in Gerung District, West Lombok Regency
Authors: Hamdani Hafiz , Pujiastuti Heni
Published: October 2022

Improving road access is very important to support human activities. One of them is improving the quality of environmental roads in Gerung District, West Lombok Regency. To make it with the availability of funds which cannot cover the entire segment in one time, that’s why priority handling is needed. This paper intends to determine the number of environmental roads in Gerung District; to know the priority of handling with SDI survey; and create a handling priority map using GIS. Based on the results, it was found that the number of environmental roads in Gerung District was 987 sections spread over 11 villages and 3 sub-districts. Handling priority of environmental road determined by the classification of road conditions as follows: good, medium, lightly damaged and heavily damaged. The number of roads based on this classification are: 568 segments for good condition; 131 segments for medium conditions; 200 segments for lightly damage; and 88 sections for heavily damaged conditions. In the map, each road segment assigned with colour identity according to its conditions and handling priorities using QGIS. The colour identities are: yellow for good condition; orange for medium conditions; red for lightly damaged conditions; and maroon for heavily damaged conditions
Comparison of SPT and Vs-based Liquefaction Assessment on Young Volcanic Sediment: A Case Study in Bantul District of Yogyakarta, Indonesia
Authors: Amalina Anisa , Fathani Teuku , Wilopo Wahyu
Published: October 2022

On May 26, 2006, an earthquake of moment magnitude (Mw) 6.3 occurred in Yogyakarta. The damages found in Bantul were predicted to be caused by liquefaction. Moreover, liquefaction symptoms were found, such as a sand boil and lateral spreading. It inferred that the damage was controlled by the amplification factors from young volcanic sediments that are redeposited and altered volcaniclastics from the active Mount Merapi. This study compared subsurface conditions based on two field investigation methods (SPT and Shear Wave Velocity) and determined the liquefaction potential by considering groundwater and the region's seismicity. Several equations to represent the N-SPT and Vs data were also analyzed to obtain the most fitted equation. As a result, several equations used in this study were inadequate to properly correlate N-SPT and Vs. A comparison of safety factor values indicated that the liquefaction potential in the studied area on the Vs-based method is lower than the result from the SPT-based method
PANNACOTTA BIJI BUNGA MATAHARI (Helianthus Annuus L) BAGI VEGETARIAN
Authors: Ramadhani Stevia Tafdhila
Published: October 2022

Biji bunga matahari merupakan bahan makanan yang dapat dikonsumsi sebagai snack atau bahan campuran produk makanan. Biji bunga matahari adalah makanan yang sangat baik untuk nilai kecukupan gizi dan sering dianggap sebagai makanan ringan sehat.Pola makan vegetarian telah menjadi pola makan yang mulai banyak dipilih masyarakat seiring dengan meningkatnya pengetahuan masyarakat akan manfaat pola makan berbasis nabati untuk mengurangi risiko terhadap penyakit degeneratif. Pola makan vegetarian rentan kekurangan asupan beberapa zat gizi yaitu protein, zat besi, seng, dan vitamin B12 yang berpengaruh pada status gizi. Pola makan vegetarian telah menjadi pola makan yang mulai banyak dipilih masyarakat seiring dengan meningkatnya pengetahuan masyarakat akan manfaat pola makan berbasis nabati untuk mengurangi risiko terhadap penyakit degeneratif.
PUKIS EKSTRAK DAUN KELOR (Moringa oleifera L) SEBAGAI CEMILAN BERNUTRISI TINGGI UNTUK IBU MENYUSUI
Authors: Wahyuningtyas Tria Andari
Published: October 2022

Daun Kelor merupakan salah satu jenis sayuran yang telah diketahui masyarakat luas. Daun kelor memiliki sejuta manfaat. Berbagai penelitian telah dilakukan mengenai manfaat daun kelor bagi kesehatan dan memiliki kandungan gizi yang tinggi seperti Vitamin A, Vitamin B, Vitamin C, zat besi, kalsium dan kalium. Peminat kue tradisional di Indonesia masih cukup banyak, namun masih sedikit produk inovasi serta penambahan bahan yang memiliki nilai gizi tinggi agar produk yang dihasilkan memiliki nilai gizi yang lebih baik. Pukis merupakan kue tradisional yang masih jarang mendapat sentuhan modern atau penginovasian. Tujuan penelitian ini untuk 1) mengetahui daya terima konsumen terhadap pukis ekstrak daun kelor, 2) mengetahui kandungan gizi pukis ekstrak daun kelor per sajian. Jenis penelitian ini merupakan penelitian research and development (RD) yang menggunakan model 4D yang terdiri dari define, design, development, dan disseminate. Instrumen penelitian berupa borang uji sensoris. Hasil penelitian menunjukkan bahwa produk terbaik dengan penambahan 5% ekstrak daun kelor dan 100% sari daun kelor. Dari hasil uji mutu sensoris terhadap produk pukis daun kelor diperoleh bahwa dengan penambahan ekstrak daun kelor sebanyak 5% dapat diterima oleh konsumen. Kandungan protein yang terdapat pada pukis ekstrak daun kelor sebesar 10%, Karbohidrat 12%, Vitamin A 4%, Vitamin E 10%, Vitamin C 294%, Kalsium 9%, Zat Besi 12%, dan Zinc sebanyak 2%.
The effect of productive learning outcomes, social circumstances, economic conditions, and creativity toward entrepreneur interest among fashion department students in vocational high school
Authors: Jerusalem Mohammad Adam , Triyanto Triyanto , Kholifah Nur , Susanti Miladiah , Ningsih Ratna Utami , Silaen Sylvia Martha Aprilia
Published: October 2022

The objectives of this research are to know the effect of productive learning, social situation, economic situation, and creativity towards the interest in entrepreneurship for students of class XII of Clothing Vocational Schools in Yogyakarta in 2018/2019. The method in this study is a correlational method with a quantitative approach. The population of this study were students of class XII of the Clothing Vocational School in Yogyakarta City, totaling 265 students. The number of research samples is 152 students with a sampling technique of proportional random sampling. Data collection techniques were questionnaires and documentation. The results of this study show that the learning outcomes of productive, social situation, economic situation, and creativity subjects affect the interest in entrepreneurship for the SMK students in the city of Yogyakarta.
Profiles of undergraduate students reading attitude
Authors: Putro Nur Hidayanto Pancoro Setyo
Published: October 2022

The objective of this study was to examine the profiles of undergraduate students at the English Language Education Study Program of Yogyakarta State University. One hundred and one (101) students participated in this survey research. The data were collected through a reading attitude survey adapted from McKenna’s survey. Confirmatory Factor Analysis (CFA) and Latent Profile Analysis (LPA) were the main data analyses. Results from CFA confirmed that the 25 items from the survey converged into 6 factors: attitude in academic reading in print, attitude in academic reading online, attitude in academic reading in social media, attitude in recreational reading in print, attitude in recreational reading online, and attitude in recreational reading in social media reading. Then, a 2-profile solution from LPA led to a conclusion that the students can be divided into two groups, i.e. students with positive attitude towards reading in one group and students with less positive attitude towards reading in the other group.Keywords: reading attitude, latent profile analysis, reading modeProfil sikap membaca mahasiswa S1AbstrakPenelitian ini bertujuan untuk mengetahui profil mahasiswa program sarjana pada Program Studi Pendidikan Bahasa Inggris Universitas Negeri Yogyakarta. Seratus satu (101) siswa berpartisipasi dalam penelitian survei ini. Data dikumpulkan melalui survei sikap membaca yang diadaptasi dari survei McKenna. Analisis data yang digunakan dalam penelitian ini antara lain Faktor Konfirmatori (CFA) dan Analisis Profil Laten (LPA). Hasil dari CFA menegaskan bahwa 25 item dari survei berkumpul menjadi 6 faktor: sikap dalam membaca akademik di media cetak, sikap dalam membaca akademik online, sikap dalam membaca akademik di media sosial, sikap dalam membaca rekreasi di media cetak, sikap dalam membaca rekreasi online, dan sikap dalam membaca rekreasional dalam membaca media sosial. Kemudian, solusi 2 profil dari LPA menghasilkan kesimpulan bahwa siswa dapat dibagi menjadi dua kelompok, yaitu siswa dengan sikap positif terhadap membaca dalam satu kelompok dan siswa dengan sikap kurang positif terhadap membaca di kelompok lain.Kata kunci: sikap membaca, analisis profil laten, mode membaca
Penyiapan kepemimpinan berdasarkan konsep Islam Jawa dalam Serat Wulang Putra karya Pakubuwana IX
Authors: Widyastuti Sri Harti
Published: October 2022

Konsep penyiapan kepemimpinan dimaknai sebagai ide atau gambaran mental masyarakat Jawa berdasarkan tradisi Islam dan tradisi Jawa untuk menyiapkan seseorang menjadi raja, penguasa, atau pemimpin. Ide atau gambaran mental tersebut diwujudkan melalui karya sastra, yakni Serat Piwulang. Penelitian ini bertujuan untuk menjelaskan konsep-konsep penyiapan kepemimpinan yang terdapat dalam Serat Wulang Putra. Sumber data penelitian adalah Serat Wulang Putra karya Paku Buwana IX. Berdasarkan prinsip filologi modern, langkah penelitian yang dilakukan yaitu (a) trasliterasi sandar, (b) penerjemahan isi, (c) pembacaan heuristik, dan (d) pembacaan hermenutik. Hasil penelitian menunjukkan bahwa terdapat tiga konsep penyiapan kepemimpinan berdasarkan perspektif Islam Jawa pada Serat Wulang Putra. Pertama, kekuatan penghargaan (reward power) yaitu kekuatan yang diperoleh dengan cara berusaha dekat dan rajin menghadap raja. Kedua, kekuatan untuk mencegah penolakan (oercive power) yakni penyiapan kekuasaan yang memerlukan derajat dalam pemerolehannya. Ketiga, kekuasaan yang sah (legitimate power) untuk menyiapkan kekuasaan yang dapat disahkan adalah dengan cara menempatkan legitimasi berupa wahyu. Keempat, kekuatan referensi (referent power) yaitu membiasakan untuk bergaul dengan orang-orang yang berkedudukan tinggi.Kata Kunci: serat wulang, kepemimpinan, kekuasaan, dan konsep Jawa IslamPreparation of leadership based on the concept of Javanese Islam in Serat Wulang Putra by Pakubuwana IXAbstractThe concept of leadership preparation is interpreted as an idea or mental picture of Javanese society based on Islamic tradition and Javanese tradition to prepare someone to become a king, ruler, or leader. The idea or mental picture is realized through a literary work, namely Serat Piwulang. This study aims to explain the concepts of leadership preparation contained in Serat Wulang Putra. The source of the research data is Serat Wulang Putra by Paku Buwana IX. Based on the principles of modern philology, the research steps carried out are (a) standardized transliteration, (b) content translation, (c) heuristic reading, and (d) hermeneutic reading. The results showed that there were three concepts of leadership preparation based on the Javanese Islamic perspective on Serat Wulang Putra. First, the power of appreciation (reward power) is the power that is obtained by trying to be close and diligent to face the king. Second, the power to prevent rejection (coercive power), namely the preparation of power that requires degrees in its acquisition. Third, legitimate power to prepare power that can be ratified is by placing legitimacy in the form of revelation. Fourth, referent power, which is getting used to associating with people of high position.Keywords: serat wulang, leadership, power, and the concept of Javanese Islam
Prediction of Antibody-Antigen Binding via Machine Learning: Development of Data Sets and Evaluation of Methods
Authors: Ye Chao , Hu Wenxing , Gaeta Bruno
Published: October 2022

Background

The mammalian immune system is able to generate antibodies against a huge variety of antigens, including bacteria, viruses, and toxins. The ultradeep DNA sequencing of rearranged immunoglobulin genes has considerable potential in furthering our understanding of the immune response, but it is limited by the lack of a high-throughput, sequence-based method for predicting the antigen(s) that a given immunoglobulin recognizes.

Objective

As a step toward the prediction of antibody-antigen binding from sequence data alone, we aimed to compare a range of machine learning approaches that were applied to a collated data set of antibody-antigen pairs in order to predict antibody-antigen binding from sequence data.

Methods

Data for training and testing were extracted from the Protein Data Bank and the Coronavirus Antibody Database, and additional antibody-antigen pair data were generated by using a molecular docking protocol. Several machine learning methods, including the weighted nearest neighbor method, the nearest neighbor method with the BLOSUM62 matrix, and the random forest method, were applied to the problem.

Results

The final data set contained 1157 antibodies and 57 antigens that were combined in 5041 antibody-antigen pairs. The best performance for the prediction of interactions was obtained by using the nearest neighbor method with the BLOSUM62 matrix, which resulted in around 82% accuracy on the full data set. These results provide a useful frame of reference, as well as protocols and considerations, for machine learning and data set creation in the prediction of antibody-antigen binding.

Conclusions

Several machine learning approaches were compared to predict antibody-antigen interaction from protein sequences. Both the data set (in CSV format) and the machine learning program (coded in Python) are freely available for download on GitHub.
The Use of HIV Pre- and Postexposure Prophylaxis Among a Web-Based Sample of HIV-Negative and Unknown Status Cisgender and Transgender Sexual Minority Men: Cross-sectional Study
Authors: John Steven A , Sizemore K Marie , Jimenez Ruben H , Jones S Scott , Petroll Andrew E , Rendina H Jonathon
Published: October 2022

Background

HIV disproportionately affects sexual minority men (SMM) in the United States.

Objective

We sought to determine past HIV postexposure prophylaxis (PEP) use and current and prior pre-exposure prophylaxis (PrEP) use among a web-based sample of cisgender and transgender men who have sex with men.

Methods

In 2019, HIV-negative and unknown status SMM (n=63,015) were recruited via geosocial networking apps, social media, and other web-based venues to participate in a brief eligibility screening survey. Individuals were asked about past PEP use and current and prior PrEP use. We examined associations of demographics, socioeconomic indicators, and recent club drug use with PEP and PrEP use, as well as the association between past PEP use and current and prior PrEP use using generalized linear models and multinomial logistic regression. Statistical significance was considered at P<.001, given the large sample size; 99.9% CIs are reported.

Results

Prior PEP use was reported by 11.28% (7108/63,015) of the participants, with current or prior PrEP use reported by 21.95% (13,832/63,015) and 8.12% (5118/63,015), respectively. Nearly half (3268/7108, 46%) of the past PEP users were current PrEP users, and another 39.9% (2836/7108) of the participants who reported past PEP use also reported prior PrEP use. In multivariable analysis, past PEP use was associated with current (relative risk ratio [RRR] 23.53, 99.9% CI 14.03-39.46) and prior PrEP use (RRR 52.14, 99.9% CI 29.39-92.50). Compared with White men, Black men had higher prevalence of past PEP use and current PrEP use, Latino men had higher prevalence of PEP use but no significant difference in PrEP use, and those identifying as another race or ethnicity reported higher prevalence of past PEP use and lower current PrEP use. Past PEP use and current PrEP use were highest in the Northeast, with participants in the Midwest and South reporting significantly lower PEP and PrEP use. A significant interaction of Black race by past PEP use with current PrEP use was found (RRR 0.57, 99.9% CI 0.37-0.87), indicating that Black men who previously used PEP were less likely to report current PrEP use. Participants who reported recent club drug use were significantly more likely to report past PEP use and current or prior PrEP use than those without recent club drug use.

Conclusions

PrEP use continues to be the predominant HIV prevention strategy for SMM compared with PEP use. Higher rates of past PEP use and current PrEP use among Black SMM are noteworthy, given the disproportionate burden of HIV. Nonetheless, understanding why Black men who previously used PEP are less likely to report current PrEP use is an important avenue for future research.
Cost-Effectiveness Analysis of Digital Therapeutics for Home-based Cardiac Rehabilitation for Patients with Chronic Heart Failure: Model Development and Data Analysis (Preprint)
Authors: Liu Tianyi , Zhang Wenhong , Jia Jian , Zhan Yiyang
Published: October 2022

BACKGROUND

In recent years, numerous guidelines and expert consensus have recommended the inclusion of digital technologies and products in cardiac rehabilitation. Digital Therapeutics (DTx) is based on evidence-based medicine and uses digital means for data collection and monitoring of indicators to control and optimize the treatment, management and prevention of disease.

OBJECTIVE

This study aimed to conduct an early technology assessment of digital therapeutics. Based on the evaluation methods and models of health economics, we analyze the potential cost effectiveness of digital therapeutics for home-based cardiac rehabilitation for patients with chronic heart failure from the perspective of healthcare decision makers so as to provide a basis and reference for application and the promotion of digital therapeutics.

METHODS

Markov models were constructed to simulate the outcomes of digital therapeutics for home-based cardiac rehabilitation (DT group) compared to conventional home-based cardiac rehabilitation (UC group) in patients with chronic heart failure. Model input parameters were clinical indicators and cost data. The outcome indicators were quality-adjusted life years (QALYs) and the incremental cost-effectiveness ratios (ICERs). The robustness of the evaluation methods and results was tested by sensitivity analyses. Clinical indicators, cost data, and health utility values were obtained from real-world data, including clinical study data, published literature, and public website information.

RESULTS

The Markov model simulated a time span of 10 years with the cycle set at one month, for a total of 120 cycles. The results showed that the per capita cost of UC group was 38,442.11 RMB/year, with a QALY of 0.7196 per person per year. The per capita cost of DT group was 42,300.26 RMB/year, with a QALY of 0.81687 per person per year. The ICER per person was 39,663.5 RMB/QALY each year, which was below the willingness-to-pay threshold of 80,976 RMB (China's GDP per capita in 2021).

CONCLUSIONS

Digital therapeutics for home-based cardiac rehabilitation is an extremely cost-effective rehabilitation option compared to conventional home-based cardiac rehabilitation. From the perspective of health care decision makers, digital therapeutics for home-based cardiac rehabilitation is potentially valuable.
Students with Intellectual Disabilities in the Context of Higher Education
Authors: Chahini Thelma Helena Costa , Junior João Batista Bottentuit , Carvalho Conceição de Maria Belfort de , Silva Naysa Christine Serra , Chahini Priscila Milena Costa , Silva Sâmya Carolyne Gonçalves da
Published: October 2022

This article aims to describe the teaching-learning process of students with intellectual disabilities at the Federal University of Maranhão (UFMA). An exploratory, descriptive research with a qualitative approach was developed with students with intellectual disabilities with active enrollment in undergraduate courses at Campus Dom Delgado. Data were collected through semi-structured interviews, through a script, containing 11 questions - related to the teaching-learning process of students with intellectual disabilities in Higher Education. The results indicate that the students entered the university through the quota system offered by the Unified Selection System (SISU)/National High School Exam (ENEM); are not receiving specialized educational assistance; do not know DACES and do not feel covered by Inclusive Education at UFMA, because although UFMA has a good structure to operationalize the inclusion process, it still lacks qualified teachers in the area of Special/Inclusive Education.
ВЛИЯНИЕ ВАКУУМНОГО СОСТОЯНИЯ НА АВТОЭМИССИОННЫЕ СВОЙСТВА КПУ МАГНЕТРОНОВ С МГНОВЕННОЙ ГОТОВНОСТЬЮ
Authors: Ли И.П. , Капустин В.И. , Шуманов А.В. , Бычков Д.В. , Леденцова Н.Е. , Полунина А.А. , Поляков Ю.В.
Published: October 2022

Вакуумное состояние играет важную роль в работе электровакуумных СВЧ-приборов. Этот параметр оказывает определяющее влияние на эмиссионные свойства катодов в приборах, поэтому важно определить уровень максимально допустимого давления остаточных газов. В данной статье представлены результаты исследования влияния вакуумного состояния на автоэлектронную эмиссию катодов безнакальных магнетронов.
Semirings of graphs: homomorphisms and applications in network problems
Authors: Rahman Saifur
Published: October 2022

This paper deals with studying some algebraic structures of the graphs as an attempt to visualize abstract mathematics. We have used some binary graph operations to investigated the algebraic structures of graphs with examples. This work emphasizes specifically the construction of semigroup or monoid and semiring, and their properties. This manuscript also aims to give a focused introduction of a class of homomorphism on the semiring of graphs. Some instances of real-life decision problems are consequently discussed. This article is also in a nascent stage of relating number theory and graph theory through mappings.
Cajas de huevos y esferas como herramienta didáctica en explicación del principio de Aufbau
Authors: Soto-Ospina Alejandro , Castro Lina Marcela
Published: October 2022

Los diagramas de configuración electrónica son esquemas que permiten explicar algunas propiedades de los elementos en la tabla periódica, teniendo en cuenta el movimiento y llenado de electrones en los orbitales según las reglas de Hund, para entender conceptos a nivel electrónico como electronegatividad, efecto de apantallamiento de los electrones, energía de ionización, carga nuclear efectiva, entre otros. Como principal objetivo se tiene que, a partir del aprendizaje activo y significativo, los estudiantes puedan hacer accesible un sistema tan abstracto y complejo desde el trabajo en el aula en su saber hacer, para ello se utilizan cajas de huevo como material reciclable que representarán los orbitales y bolas de ping-pong para representar los electrones como modelo corpuscular; este modelo se aplica en las aulas de clase para explicar datos numéricos de la energía de ionización como propiedad periódica que se desea entender. Los modelos fueron bien asimilados para la muestra de estudiantes evaluados y permitió generar discusiones dentro del aula de clase, espacios argumentativos y descripción de modelos o predicción de modelos bajo una conceptualización didáctica grupal.
Más allá de los límites. Latinoamérica y la historia de la fotografía
Authors: Suescún Monroy Pilar
Published: October 2022

La historia de la fotografía, tradicionalmente, la han escrito las naciones dominantes. En un principio, el enfoque fue, sobre todo, técnico y eurocéntrico, pero también estadounidense, a partir de la Historia de la fotografía de Newhall. El presente artículo revisa algunos textos que forman parte de la historiografía de la fotografía, y busca identificar cómo se formó el concepto de fotografía latinoamericana.
Additional Considerations in the Treatment of Diabetic Nephropathy Based on the KDOQI Clinical Practice Guideline
Authors: Rico Fontalvo Jorge , Montejo Hernández Juan David , Daza Arnedo Rodrigo , Cabrales Jose
Published: October 2022

Obesity is a risk factor for the development and progression of CKD, which has been shown in numerous studies. The mechanism of how this occurs is not completely understood, but several putative mechanisms proposed via adiposity, include low adiponectin high leptin and resistin, causing inflammation, insulin resistance, RAAS activation and oxidative stress, leading to CKD; in addition, it also causes diabetes mellitus, hypertension, and cardiovascular disease. Obesity is a persistent inflammatory state, and inflammation has been shown to play an important role in the development and progression of diabetic kidney disease, hence controlling obesity has become a key component as a preventative strategy in the development of kidney disease.
Wide diversity of pollens in honey samples from Indian Himalayan neighbourhoods: a melissopalynological study
Authors: Kumari Vandana , Mattu Neelam , Thakur Pankaj , Lakhanpal Dinesh , Mattu Vinod K.
Published: October 2022

Melissopalynological analysis of 34 honey samples (17 summer and 17 autumn samples) collected from feral colonies of Indian hive bee (Apis cerana), European bee (Apis mellifera) and rock bee (Apis dorsata) during 2011 – 2015 from the Shimla Hills of Himachal Pradesh (India) was performed. Pollen from plant taxa belonging to 43 families was found in the honey samples. Of 34 honey samples from the Shimla Hills, 18 were unifloral with 12 pollen types as predominant and the remaining 16 samples were multifloral. The predominant pollen plant taxa of summer were Pyrus sp., Malus domestica, Prunus amygdalus, Prunus sp., Eucalyptus camaldulensis, Citrus sp. and Rhododendron arboreum. In autumn, the predominant pollen plant taxa were Leucaena leucocephala, Salvia officinalis, Eriobotrya japonica, Impatiens balsamina and Prinsepia utilis. Melissopalynological analysis of summer honey collected from Summer Hill and Sarahan tagged these as “mad honey”, since Rhododendron pollen was predominant. The pollen spectrum indicated a diverse bee plant flora, which is promising indicator to augment the beekeeping industry in this region.
Efflux-mediated ciprofloxacin and cefixime resistance in Pseudomonas aeruginosa
Authors: Mini Minsa , Sreekantan Abhirami P. , Manikandan Arya K. , Mohanan Archana G. , Khan Sajeeb , Kumar Praveen
Published: October 2022

Pseudomonas aeruginosa is a gram-negative, motile and clinically relevant bacterium. It is a significant pathogen associated with immunosuppression, cystic fibrosis and malignancy. Infections due to multidrug-resistant P. aeruginosa cause greater morbidity, death rate, and increased healthcare expenses. Drug efflux is a prevalent mechanism of antibiotic resistance in P. aeruginosa. The objective of the study was to analyze the antibiotic susceptibility profile of a clinical strain of P. aeruginosa (GC14) and to identify the mechanism of antibiotic resistance. The antibiotic resistance of GC14 was tested against 19 antibiotics using an antibiotic susceptibility test. A polymerase chain reaction-based strategy was employed to detect the presence of mexB, mexD and mexY efflux pump genes. The efflux pump inhibition assay was conducted to analyze the effect of efflux pumps on antibiotic resistance in GC14, using carbonyl cyanide m‑chlorophenyl hydrazone (CCCP) as an efflux pump inhibitor. The antibiotic susceptibility test confirmed that GC14 is multidrug-resistant and showed resistance to tetracycline, cefixime, ciprofloxacin, erythromycin, meropenem, azithromycin, doxycycline, aztreonam, co-trimoxazole and gentamycin. The genes encoding transporter protein viz. mexB, mexD and mexY were amplified successfully from P. aeruginosa, revealing the presence of efflux pump genes. The data obtained from the efflux inhibition assay using CCCP showed that efflux pumps play a significant role in ciprofloxacin and cefixime resistance. The study emphasizes the importance of efflux pumps in antibiotic resistance and also confers the necessity of continuous surveillance and regular monitoring of the emergence of multidrug-resistant isolates of P. aeruginosa.
Microbial biosurfactants: prospects of sustainable molecules with promising applications in bioremediation
Authors: Berkat Samir , Meliani Amina , Mazari Hibat Errahmèn , Aliane Samia
Published: October 2022

The dispersal of various chemical pollutants in our environment requires the development of effective approaches that would lead to the bioremediation of contaminated areas. The biological methods such as the application of microbial biosurfactants represent one of the suitable solutions that has gained large attention due to their structural diversity, molecular sizes, and multifunctional characteristics. Thus, they are likely to be applied in the field of bioremediation, where they can lower the surface and interfacial tensions at different interfaces leading to removal of pollutants or improve their biodegradation and bioavailability. The presented review highlights the recent advances and knowledge on the important aspects of microbial biosurfactant applications in bioremediation.
Histomorphological features of the thyroid gland in rats of different ages with alimentary-induced obesity
Authors: Yanko Roman , Levashov Mikhail
Published: October 2022

The aim of the study was to compare histomorphological disorders of the thyroid gland in rats of different ages with alimentary-induced obesity. The study was carried out on male Wistar rats, aged six and 21 months. Alimentary obesity in animals was modelled by keeping them on a high-calorie diet (580 kcal 100 g‑1) for 12 weeks, with an excess content of fats and carbohydrates. Control animals were given a standard diet (330 kcal 100 g‑1). Histological preparations were made from thyroid tissue. Histomorphometry was carried out using the computer program “ImageJ”. It was revealed that a 3‑month high-calorie diet led to the appearance of pronounced histomorphological signs of thyroid hypofunction in rats. Intensive colloid resorption and a decrease in colloid area occurred in the gland. Devastated follicles were common. Thyrocytes acquired a prismatic shape. There was hyperplasia of the thyroid gland, which led to an increase in its size. The intensity of morphological disorders of the thyroid gland depended on the degree of obesity and had a distinct age-dependent character. In young rats, these changes were more pronounced than in older animals.
Akulturasi Islam dan Budaya Mistik Kampung Keramat Bekasi dalam Perspektif Sejarah
Authors: Adam Yusril Fahmi
Published: October 2022

Abstract: This article is a historical research that aims to analyze the phenomenon of acculturation of Islam and mystical culture in the Keramat Village, Bekasi. This article uses historical methods, anthropological approaches, and acculturation theories of culture. This article is not only narrative-descriptive, but also analytical-descriptive. The findings in this article indicate that there are problems in the religious aspect that intersect with the local culture that develops in the community of Kampung Keramat Bekasi. Local people believe in mystical things, such as worship on petilasan and objects that are considered to have supernatural powers. Therefore, there are efforts from Muslims including the initiative of local scholars to eliminate these mystical beliefs with an Islamic acculturation approach. In the end, the mystical culture that is similar to animism-dynamism slowly fades and even disappears in the current contemporary era, on the other hand, the people around Kampung Keramat Bekasi also have the awareness to implement Islamic law based on the Qur'an and HadithAbstrak: Artikel ini merupakan penelitian sejarah yang bertujuan untuk menganalisis fenomena akulturasi Islam dan budaya mistik yang berada di Kampung Keramat Bekasi. Di dalam analisisnya, artikel ini menggunakan metode sejarah, pendekatan antropologi, serta teori akulturasi budaya. Dengan metodologi yang digunakan, artikel ini tidak hanya bersifat naratif-deskriptif, melainkan lebih kepada analitis-deskriptif. Temuan dalam artikel ini adalah terdapatnya permasalahan di dalam aspek keagamaan yang beririsan dengan budaya lokal yang berkembang di dalam masyarakat Kampung Keramat Bekasi. Budaya lokal yang melekat di dalam masyarakat setempat adalah adanya kepercayaan terhadap hal-hal mistis, seperti pemujaan di atas petilasan serta benda-benda yang dinilai memiliki kekuatan ghaib. Oleh karena itu, terdapat upaya dari umat Islam atas inisiatif ulama setempat untuk menghilangkan kepercayaan mistik tersebut dengan pendekatan akulturasi Islam. Pada akhirnya, budaya mistik yang serupa dengan animisme-dinamisme tersebut perlahan memudar bahkan menghilang di era kontemporer saat ini, dan juga masyarakat sekitar Kampung Keramat Bekasi telah memiliki kesadaran akan pentingnya syariat Islam berdasarkan al-Qur’an dan Hadits
“Todo mundo tem história?”: experiências de ex-internos em hospital psiquiátrico
Authors: MIRANDA G. , ZAMBENEDETTI Gustavo
Published: October 2022

The Psychiatric Reform progressively seeks to shift the focus of hospital care to territorial care networks. The objective of this study was to understand the experience of people in severe psychic suffering about hospitalization and post- hospitalization in a psychiatric hospital. A qualitative study was conducted, using the Focal Life History method, with interviews with 5 former inmates of the extinct Franco da Rocha Psychiatric Hospital (HPFR). Through the Content Analysis Theme, three categories were raised: the way to relate to madness, the ambivalence of experiences and the nuances of a possible break of paradigms. Such categories allowed to discuss the coexistence between the asylum and psychosocial paradigms in the current scenario of Psychiatric Reform, constituting crossings in the ways of composing itineraries of care between people with psychic suffering. It is stated a need for the production of ways of care that respect the right to citizenship, the word and the history of people with psychic suffering.
distinguishing
Authors: Dantas Júnior João Fabrício
Published: October 2022

Objetivo: focada na Hermenêutica Jurídica e na adequada prestação jurisdicional, a pesquisa objetiva traçar elementos do precedente judicial, como um todo, e do distinguishing, como objeto específico, sob o sistema de precedentes obrigatórios adotado pelo Código de Processo Civil brasileiro. O argumento de distinção impõe a busca de elementos de sua natureza jurídica, de seus limites e, ainda, de como o sistema de precedentes reforçou a importância da atividade interpretativa e argumentativa em casos em que se pretende afastar a aplicação de um precedente. Método: metodologicamente, utilizou-se de fontes normativas, doutrinárias e jurisprudenciais para alcançar como o argumento dodistinguishing, diante de um precedente, apresenta-se como ferramenta de cooperação para a celeridade procedimental, a segurança jurídica, a coesão jurisdicional e, ainda, de defesa do próprio devido processo legal. Resultado: como resultados, a pesquisa visa alcançar como o sistema de precedentes e ainda o argumento do distinguishing velaram pela isonomia constitucional e, portanto, também pela dignidade. Tanto a técnica de julgamento com fundamentação vinculada como, ainda, o distinguishing, enquanto método de controle e interpretação do sistema, encorajaram a pesquisa sobre princípios processuais e sobre como esses continuam respeitados no modelo de cooperação processual atualmente adotado. O distinguishng, assim, ganha roupagem de garantia constitucional, diante de uma violação aodevido processo.
Value of left ventricle mechanical dyssynchrony and scar burden in combined assessment of factors associated with cardiac resynchronization therapy response
Authors: Atabekov Tariel A. , Mishkina Anna I. , Batalov Roman E. , Sazonova Svetlana I. , Krivolapov Sergey N. , Saushkin Victor V. , Khlynin Mikhail , Varlamova Yulia , Curnis Antonio , Zavadovsky Konstantin V. , Popov Sergey
Published: October 2022

Introduction: The cardiac resynchronization therapy (CRT)
improves outcome in patients with heart failure (HF). However
approximately 30% of patients are non-responsive to CRT. The purpose of
this study was to investigate the role of the left ventricle (LV)
mechanical dyssynchrony (MD) and scar burden assessment as predictors of
CRT response. Methods: We included in the study 56 sinus rhythm
patients (male 35 [62.5 %], mean age 57.0 ± 11.5 years) with
ischemic or nonischemic HF, and left bundle branch block with QRS
duration ≥ 150 ms who underwent CRT-D implantation. Echocardiography,
full physical examination, myocardial perfusion imaging (MPI) with
Tc-methoxy-isobutyl-isonitrile and gated blood pool
single-photon emission computed tomography (gBPS) were performed at
baseline and at 6-month follow-up. Patients were grouped based on the
response to CRT assessed by echocardiography. Results:
Forty-five patients (80.3 %) were responder (RESP) and 11 (19.7 %)
were non-responder (non-RESP) to CRT. RESP patients had higher LV
anterior wall standard deviation (LV AW_SD) (p=0.0001) and lower summed
rest score (SRS) (p=0.018) than non-RESP subjects. In multivariate
logistic regression, LV AW_SD (adjusted odds ratio [OR] 1.5275;
95% confidence interval [CI] 1.1472-2.0340; p=0.0037), SRS (OR
0.7299; 95% CI 0.5627-0.9469; p=0.0178) and HF non-ischemic etiology
(OR 20.1425; 95% CI 1.2719-318.9961; p=0.0331) were independent
predictors of CRT response. Conclusion: Ventricle dyssynchrony
and scar burden assessed by cardiac gBPS and MPI are associated with
response to CRT. Further investigations of their predictive significance
are warranted.
The reporting requirements of case reports and adherence of Case report reporting guidelines in journals publishing most of case reports: an analysis of the authors’ guide sections
Authors: Taheri Abolfazl , Adibi Peyman , Abbasi Alireza , Jaffari Mo Sabbagh , Saeedizadeh Marziyeh , Rahimi Alireza
Published: October 2022

Top 50 medical SCOPUS-Indexed journals publishing case reports have been
analyzed in order to identify the reporting requirements and emerging
typologies. Reporting requirements are grouped in: (1) reasons for
publishing,(2) patient consent and confidentiality,(3) word limitation,
and (4) recommendation for the structure and reporting elements. Also,
13 types were identified.
Code Switching Used by Agnes Monica on Deddy Corbuzier’s Podcast
Authors: Rapini Ni Komang
Published: October 2022

Code-switching is important and widely used, someone feels they have to change the language used in order to communicate well and smoothly between each other. The research was conducted with the aim to analyses the types of Code-Switching used in Video Podcasts on the Deddy Corbuzier Channel with Agnes Monica. The data analysis technique used is descriptive qualitative with in-depth analysis techniques about the types of Code-Switching. Some methods in collecting data such as, searching the video, watch the video carefully and analyze the code-swtching. After analyzing, the researcher found the 40 data and the researcher got Inter-sentential switching 12(30%), Intra-sentential switching 8(20%), Tag-switching 3(8%) and Intra-word Switching 17 (42%) and the Intra-word Switching is dominant type of code switching used by Agnez Monica on podcast Deddy Corbuzier in YouTube. The data with persentage 36% from 9 data.
Panaik Money of Bugis’ Customary Marriage in the Perspective of Islamic Law and Positive Law in Indonesia
Authors: Jannah Shofiatul , CH Mufidah , Suwandi Suwandi
Published: October 2022

This article discusses the giving of panaik money to the Bugis marriage customs outside of the dowry obligation. This culture has long been carried out at traditional Bugis weddings. The custom of giving panaik money has become a topic of discussion among academics because it is not included in the pillars and conditions of marriage in Islam or positive law. This is a custom that is sometimes considered burdensome to the prospective groom to cause the marriage to be annulled. This research is library research with a normative approach. It uses a qualitative method, namely, observing and reviewing the obligation to give money for traditional Bugis marriages outside of the dowry. The results of the panaik money research in the study of Islamic law do not conflict with the terms and pillars of marriage. As for the positive legal view, in this case, Law Number 1 of 1974 concerning Marriage concludes that panaik money does not conflict with formal or material requirements, namely in articles 6 to 10, which explain the existence of cultural fusion between customary law and Islamic law in Indonesia which has been recognized. As part of the source of material law in Indonesia. As for the cultural pattern of Bugis ethnic marriage, panaik money is a form of respect and appreciation from the male family to the female family.Panaik Money, Islamic Law, Positive Law, Cultural Customs