bluuebunny/crossref_metadata_2025 huggingface dataset:
Consumer Preferences and Reactions to Brand Expansion
Authors: Vuković Dijana , Kerum Fani , Žukina Miroslava
Published: July 2024

Consumer purchasing power is one of the key determinants of consumer behavior, among other factors. Acceptance of new brands or product line extensions of existing brands is influenced by perceived value. New products can be added to existing product lines by introducing new products within them, or brands can expand horizontally by entering entirely new categories or product lines. Any vertical expansion, whether to a higher or lower level, comes after a price shift and a product quality achievement relative to its base product. While survey-based research provides valuable insights that support the growth of the Premium brand, building a strong relationship with customers, quickly identifying preferences, personalizing the offer and fostering a climate of trust remain its main sources of value. The purpose of the paper is to show the positive relationship that exists between the vertical growth of the brand and the increase in customer loyalty, as shown by the research conducted on a deliberate sample.
Do Wages Follow Productivity? Evidence from European Countries
Authors: Kosuliev Aleksandar
Published: July 2024

Economic theory assumes that factors are paid according to their marginal productivity, however the empirical validity of this hypothesis has been questioned in some of the literature. We use data from Eurostat to examine the changes of labour remuneration and labour productivity during the period 2004-2020 in a panel of European countries. The results from the panel regression analysis confirm that in general there is a strong link between labour productivity and the compensation of employees. However, exploratory analysis shows that the sample is characterized with internal heterogeneity. Growth is higher in Central and Eastern Europe and for some countries from the region there is decoupling of productivity and labour remuneration. The latter has seen stronger growth, with the exception of Romania, where in real terms productivity has been growing faster than wages. Possible explanations of the decoupling are catching up and convergence, integration in the world economy, factor mobility, difference in labour market institutions and excessive labour demand, but the present research is inconclusive.
Future Challenges of Implementing Innovative Business Model in the Automotive Industry
Authors: Băbeanu Sabin-Alexandru
Published: July 2024

The innovative business model is implemented today in all industries. In the automotive industry, this model appears as a valid source of guidance in smart manufacturing, but also in the sales process, throughout the functional lifetime of a car. Using digital business processes opens new opportunities for innovation, from simple automation implementations to a fully automated assembly of a production line or a digitized sales flow.

Specific objectives of this paper are based on the research of specialized literature regarding the implementation of business processes and the preparation of the environment for Industrial Revolution 6.0, by integrating innovations with major implementation challenges in the business model.

The purpose of this study is to identify if there is research on innovative business models or innovative processes in specialized literature.

Research questions are related to the terms associated with innovation such as an innovative business model, industrial revolutions, digital ecosystems, smart factories, or digital business processes. The research was carried out with the help of bibliometric analysis of scientific articles in Web of Science. Articles were analyzed in the VOSviewer application by identifying several clusters on key concepts. Innovative business studies in the automotive industry is a model that led to the creation of links maps between articles on the same topic, keywords, authors, in the last five years.

Connections between the concepts and processes used to implement the innovative business model, in different stages of the industrial revolution development are highlighted in this research.
A Bibliometric Analysis of Knowledge Dynamics and Open Innovation Process
Authors: Camară Andreea Bianca
Published: July 2024

The article investigates from an analytical perspective the relationship between knowledge dynamics and open innovation and their influence on today's business environment. The present study starts from the premise that the development of a fluid and constant flow of knowledge exchange outside the organization influences the processes of open innovation. Allowing the rapid adaptation of organizations to the new effervescent demands of the market and consumers. The addition brought by this paper represents a conceptual expansion of the need to understand the possible implications of external and internal knowledge, of a rational, emotional, or spiritual nature, on the processes of development of new strategies, products, and services. There is no substantial information available in the specialized literature about the two concepts, which highlights the need to develop more qualitative and quantitative research in this direction. Using the bibliometric analysis with VOSviewer software, the paper presents a series of results that can be further developed and analyzed. The first perspective highlighted by this study is the potential of emotional, rational, and spiritual knowledge to improve relationships with consumers as a result of implementing a constant flow of communication. This fact is supported by the symbiotic relationship between the role of knowledge dynamics in encouraging the exchange of knowledge between consumers and organizations that stimulates an open, transparent communication environment focused on continuous learning. The study also emphasizes the involvement of collaboration, adaptability, and dynamic capabilities to explore how knowledge dynamics influence and stimulate innovative culture.
Professional Skills of Future Accountants Working in a Digitized Environment Dominated by ERP Systems or Artificial Intelligence
Authors: Barna Laura-Eugenia-Lavinia , Ionescu Bogdan-Ștefan , Hurducaci Gorea Corina-Cătălina
Published: July 2024

The massive evolution of the digitization concept in recent years has also gained momentum among accounting professionals, as a result of the massive use of IT systems called ERP (Enterprise Resource Planning) systems. Thus, their entire activity is focused on the processing of financial-accounting data with the help of ERP (Enterprise Resource Planning) systems. The modular structure of ERP (Enterprise Resource Planning) systems can be integrated for other departments within an organization, but in this article the financial-accounting module of the ERP (Enterprise Resource Planning) system will be discussed, in order to identify the main skills of future accountants. Artificial Intelligence, and learning algorithms in particular, offer exciting opportunities to help professionals such as accountants improve their skills, the way they deliver services and the way they create value.

The research method used for this article is quantitative, based on the bibliometric analysis of the digitization of the accounting profession, focusing primarily on what skills future accountants should develop. The sample of articles used for the analysis was selected from the Web of Science platform, then to be analyzed using the VOS viewer application. The results obtained indicate a significant increase in the analysis capacity of the future accountants, greatly reducing the part of manual data processing that they did manually in the past.

The conclusion of the article demonstrates how much the activities of professional accountants have evolved as a result of the digitization of their activities, using ERP (Enterprise Resource Planning) systems or Artificial Intelligence.
Evolution of the Agricultural Legislation in Albania: Relevant Criminal Profile
Authors: Hyna Eva , Bozheku Enida
Published: July 2024

Abstract.

Albania, after the fall of the dictatorial system in 90’, has faced numerous challenges in relation to the development of his own agricultural legislation. The current status of Albania, as a negotiating candidate country for the EU, has increased the obligations and responsibilities of the State in the adoption of laws and national strategies focus on agriculture. Thanks to international projects and partners, Albania, only in the latest years has managed the reformation of its agricultural system. The difficulties resulting from mass immigration, property conflicts, the creation of a sustainable economy organized in family businesses of the SME typology, the mechanization of the agricultural economy, investments in technological innovation, as well as closely related problems that directly affect the development of Albanian agriculture, present concern and need solutions. Misuse of funds, fraud or corruption related to the implementation of international agricultural financing programs present a problem in guaranteeing security and right access to agricultural support system and schemes. Beyond the difficulties, the goal is that in the European journey, Albania can raise its competitive abilities in the E.U. market, implementing the best community policies. The research methodology used is based on empirical (quantitative) data obtained from the Albanian and foreign Statistical Institutes, as well as on the objective analysis of these data in a comparative relationship between them.
Role of Audit Committees and Internal Audit in the Context of the Evolution of ESG Indicators
Authors: Olteanu Burcă Andreea Larisa , Badea Florea Elena Claudia , Preda Mădălina
Published: July 2024

The purpose of this research is to analyze the role and correlation between audit committees and internal audit within companies, in the context of environmental, social and governance (ESG) evolution of indicators in the information industry.

Design/methodology/approach - This paper aims to understand whether there is a correlation between these 3 indicators (audit committee, internal audit and ESG indicators) and what is the impact on ESG score. The reported data is collected from a sample of companies included in the Refinitiv Eikon database and analyzed using a panel data analysis at both regional and industry levels.

The sample is composed of the number 889 companies, from Europe, most of them members of the European Union and covers a period of 4 years, from 2019 to 2022.

The results of this study show that AC and internal audit have a significant positive impact on sustainability disclosure, highlighting the positive impact of reporting according to GRI guidelines, the efficiency of internal audit and the independence of the audit committee.

This research contributes to the literature on sustainability reporting by information industry companies, in which regulators do not play a dominant role in determining the degree of disclosure. In the future, it will be necessary to have more involvement in determining these companies to have a greater responsibility regarding the transparency of reporting.
The Impact of Multiple Crises on the Economy. A Comparative Analysis of GFC, COVID-19 and the Ukraine War Period
Authors: Ene Giorgiana-Roxana
Published: July 2024

This paper aims to analyze the correlation between the gross domestic product (GDP) and its components as well as the Harmonized Consumer Price Index (HICP) total, electricity and gas by deploying principal components analysis and factor analysis on wards linkage and compare the results for GFC period, COVID-19 pandemic and the war in Ukraine period for EU27, Romania, Greece, Italy and Hungary. The result obtained show that each crisis has its specificity given their different source, GFC was borne in the financial system the COVID-19 crisis in the medical crisis and the war in Ukraine a military one and that starting with 2020 the economy has faced multiple crisis. Government consumption is found to be one of the significant variables for all crisis as a result of the efforts made by the governments to limit the negative effects of the GFC, pandemic and the war in Ukraine and HICP electricity and HICP gas due to the impact of COVID-19 on the supply chain prior to the war in Ukraine and the shortage of personnel, as well due to the sanctions applied to Russia and the fact that it is the main exporter for the European Union.
Statistical Model for Evaluating the Organizational Behaviour System in Online-Onsite Environments
Authors: Vîlcu Adrian , Lăzărescu Raluca-Petronela , Herghiligiu Ionuț-Viorel , Veleșcu Mădălina-Laura , Cojocaru Mariana
Published: July 2024

The study of organizational behaviour is essential for human resource managers to improve organizational efficiency, aiming to create a conducive working environment to stimulate employee engagement within the organization. By understanding the factors influencing behaviour in organizations, more effective strategies can be implemented for managing people and resources. The current research statistically models a system of individual-centred organizational behaviour [OB] in relation to influencing variables - online [MOn] and hybrid [MOh] relational environments. The systemic variable [OB] is analyzed from the perspective of three dimensions - the individual's relationship with the group they belong to [group-focused behaviour], the individual's relationship with themselves [individual-focused behaviour], and the relationship between the individual and the tasks they have to solve [task-focused behaviour]. This system is statistically modelled through the analysis of influencing factors in online and offline relationships. The current research includes an analysis of statistical modelling applied to two heterogeneous groups of students and the comparison of regression models on the two systems [OB]-[MOn] and [OB]-[MOh]. The research methodology includes the presentation of statistical data, formulation of working hypotheses, questionnaire component, application to the two groups of respondents, creation of systemic variables, analysis of variable distributions, correlational analysis, application of statistical regression, and formulation of conclusions and observations. The limitations of the research, the applicability and versatility of its methodology, and future research directions in this field are highlighted in the conclusion of the work.
Panels of Cold-Formed Steel Profiles: Possibility of Their Use to Repair War-Damaged Large-Panel Buildings
Authors: Semko Volodymyr , Hranko Olena , Ároch Rudolf
Published: July 2024

In the paper, we present the results of an analysis of data samples of 282 damaged buildings; the samples include the age of the building, the type of vertical bearing structures, the type of construction of the external walls, the method of the insulation of the walls, the number of floors, the buildings’ functions, and the extent of the damage. The primary objective of the analysis was to evaluate the possibility of using panels of cold-formed thin-walled steel profiles to repair the damaged structures. The results of a study of typical projects of large panel buildings that were constructed in Ukraine and an analysis of the practical experience of repairing these types of buildings after blast actions can also be found. The research tasks are defined for implementing this technology in the process of repairing large panel buildings.
ANALISIS OPEN INNOVATION DITINJAU DARI PERSPEKTIF RESOURCE BASED VIEW (RBV) THEORY
Authors: Yulianti Prima , Masruri Masruri
Published: July 2024

Companies adopt open innovation to improve company performance. The level of openness of MSMEs, whose resources and capacities are different from those of large companies, is still underrepresented and receives little attention. Resource-Based View (RBV) Theory states that unique and rare resources become a competitive advantage for companies. This research aims to analyze open innovation, based on human capital, knowledge sharing, social media and its impact on business performance from a Resource-Based View Theory perspective. The sample was 162 respondents from MSMEs in Padang City. The sample determination technique is purposive sampling. The method used is a quantitative method, then processed and analyzed using the structural equation modeling (SEM) data analysis technique model with smartPLS. The findings in this research are that there is a positive and significant influence of human capital and social media on open innovation, while knowledge sharing does not have a positive and significant influence on open innovation. Apart from that, open innovation has succeeded in mediating the relationship between human capital and business performance. However, it was not successful in mediating the relationship between knowledge sharing and social media on business performance. It is hoped that this research can be used by business actors in determining policies to innovate and improve the performance of MSMEs in the future
REAKSI PASAR TERHADAP PERISTIWA STOCK SPLIT DI MASA PANDEMI COVID-19
Authors: Aprilia Agung Istri , Badjra Ida Bagus , Dana I Made , Gede Suasana I Gusti Agung Ketut
Published: July 2024

A stock split is a corporate action that results in a change in the nominal value per share and increases the number of outstanding shares in accordance with the split factor. This study aims to test and analyze whether there are differences in abnormal stock returns and trading volume activity between before and after the stock split event during the Covid-19 pandemic for companies on the Indonesia Stock Exchange. This study uses a quantitative approach with the event study method and a window period of 15 days. The research sample was based on a purposive sampling technique, namely 10 companies out of 12 population companies that had stock splits on the Indonesia Stock Exchange. The analysis technique uses the mean difference test technique, namely the paired sample t-test for abnormal returns, and the Wilcoxon signed rank test for trading volume activity. The results showed that there were differences in abnormal stock returns and trading volume activity before and after the stock split. The average value of abnormal stock returns and trading volume activity before the stock split was higher than after the stock split. Research has implications for all parties as input and consideration in making decisions amid uncertain market conditions.
PENGARUH STRATEGI DIFERENSIASI TERHADAP KINERJA UMKM: KEUNGGULAN KOMPETITIF SEBAGAI MEDIATOR
Authors: Nisa Sri Hijratun , Animah Animah
Published: July 2024

Penelitian ini mengeksplorasi bagaimana strategi diferensiasi mempengaruhi hasil kinerja usaha mikro, kecil, dan menengah (UMKM) di bidang kreatif kerajinan emas mutiara di Kota Mataram. Penelitian ini didasarkan pada teori resource-based view (RBV). Keunggulan kompetitif digunakan sebagai variabel mediator dalam hubungan tersebut. Data dikumpulkan dari 57 pengrajin UMKM industri kerajinan emas mutiara di Sentra Kerajinan Sekarbela, Kota Mataram. Data dianalisis dengan menggunakan metode kuantitatif dan analisis jalur. Hasil penelitian menunjukkan bahwa strategi diferensiasi berpengaruh positif dan signifikan terhadap keunggulan bersaing dan kinerja UMKM. Keunggulan bersaing berpengaruh signifikan terhadap UMKM. Namun, keunggulan bersaing tidak terbukti memberikan pengaruh mediasi yang signifikan dalam hubungan antara strategi diferensiasi dan kinerja UMKM. Pengaruh langsung dari penerapan strategi diferensiasi terhadap kinerja UMKM melebihi pengaruh tidak langsung yang dihasilkan melalui keunggulan bersaing. Temuan ini menggarisbawahi pentingnya strategi diferensiasi dalam meningkatkan kinerja UMKM, terutama pada industri yang menekankan pada diferensiasi produk dan desain baru. Penelitian ini memberikan implikasi praktis bagi UMKM pada industri kreatif kerajinan emas mutiara di Kota Mataram dalam mengembangkan strategi diferensiasi untuk meningkatkan kinerja usaha.
WHO OWNS WILDLIFE IN URUGUAY? CONNECTIONS BETWEEN GAME MANAGEMENT AND LOCAL PERSPECTIVES ON WILDLIFE OWNERSHIP
Authors: Sciandro José , Chouhy Magdalena , Dabezies Juan Martin
Published: July 2024

The connection between the legal definition of wildlife ownership is fundamental in establishing clear and appropriate hunting regulations. Ambiguity in the terminology used to justify the need for regulations and their relationship to traditional knowledge may impede species management and conservation. Between 2013 and 2018 we studied the relationship between the hunting national framework in Uruguay with local practices and perceptions of hunting and wildlife ownership. Based on ethnographic work in Paso Centurión, a small rural town in north-eastern Uruguay, we describe local forms of environmental engagement, wildlife ownership, and the impact of developing a protected area. We highlight the importance of considering local attitudes and perceptions of hunting regulation, incorporating a broader discussion about the ownership of nature and the forms of human-wildlife relations in rural contexts.
Sex differences in skin microcirculatory vascular reactivity in experimental lipopolysaccharide-induced endotoxinemia
Authors: Chkhaidze I. Z.
Published: July 2024

Bacterial lipopolysaccharide (LPS) plays a leading role in the development of a systemic inflammatory response and endogenous intoxication. However, the sex differences in the functional state of the microcirculatory bed in LPS-induced endotoxinemia have been poorly studied. Objective. To study the characteristics of skin microcirculatory vascular reactivity in experimental LPS-induced endotoxinemia in male and female rats. Material and methods. Modeling of endotoxinemia was performed by intraperitoneal injection of LPS of the cell wall of the bacterium Salmonella enterica to male and female Wistar stock rats. Two doses of LPS were used: 50 mg/kg and 10 mg/kg. We used laser Doppler flowmetry to evaluate skin perfusion before and after LPS injection, blood flow changes under test conditions with local contact hypothermia caused by a thermoelement. Results. 48 hours after LPS injection, a decrease in blood flow was observed, especially pronounced at a dose of LPS 50 mg/kg. During the test with local cooling of the skin, a change in the kinetics of the reaction was noted. Blood flow reduction was 75% (LPS 50 mg/kg) and 51% (LPS 10 mg/kg), statistically significantly different from the control groups. At the same time, the classic phenomenon of “cold vasodilation” observed in control rats was absent in all groups with the injection of LPS. Maximum perfusion after restoration of blood flow in females was achieved 3 times faster than in males (LPS 10 mg/kg). Conclusion. In experimental LPS-induced endotoxinemia, a dose-dependent decrease in skin perfusion was revealed. We obtained new data on the absence of pronounced “cold vasodilation” at local contact hypothermia. The results of the study indicate a violation of the mechanisms of neurogenic vasoconstriction and endothelium-dependent vasodilation, reflecting systemic disorders of microcirculation regulation. At the same time, the females showed a more positive dynamics of blood flow restoration in the test with local cooling of the skin, indicating a greater functional reserve and a more effective mechanism of autoregulation of the blood microcirculation system. A functional test with local contact cooling of the skin is highly informative for assessing vascular reactivity and preservation of the autoregulation mechanism of microcirculation in modeling endogenous intoxication
A model for optimizing an investment portfolio in modern conditions
Authors: ABUZOV Artur Yu.
Published: July 2024

Subject. This article discusses the issues of improving the methodology for optimizing an investment portfolio in modern conditions.
Objectives. The article aims to develop a model for optimizing the investment portfolio, taking into account the investor's risk profile and the limited budget.
Methods. For the study, I used a comparative analysis, mathematical modeling in economics, machine learning methods, genetic algorithms, and the Python programming language.
Results. The article presents the author-developed model of optimizing the investment portfolio of an enterprise, based on the symbiosis of individual elements and principles of the most effective methods of optimizing the investment portfolio, algorithms for their implementation, mathematical model and practical recommendations.
Conclusions and Relevance. The combination of classical methods of investment portfolio optimization and machine learning in the model helps improve the accuracy of assessing the future return of assets and determine their weights in the investor's portfolio. The theoretical significance of the work lies in the fact that the scientific provisions that actualize the task of improving existing or developing new approaches to optimizing the investment portfolio are proved. The practical significance of the study lies in the fact that the presented model is of an applied nature, taking into account the risk profile of the investor, tactical and strategic goals of investment, and budget constraints. The results of the study may be of interest to novice stock market participants, experienced investors, IT specialists engaged in the creation of programs and robots for trading on the stock market using machine learning tools.
Postgraduate studies qualifying for teaching mathematics as another subject
Authors: Barańska Barbara , Zambrowska Małgorzata
Published: July 2024

The idea for the project was inspired by experiences and observations related to postgraduate studies qualifying for teaching mathematics as a second subject (PSQTM). One important goal of the project was a comprehensive analysis of the issues related to postgraduate mathematics teacher education. In the project we wanted to diagnose substantive and didactic competences of teachers taking postgraduate studies qualifying for teaching mathematics as another subject in primary and secondary school.
#BlackLivesMatter: Where Do the Paradigms of Public Administration Fit?
Authors: Sharmin Farzana , Sunga Janek
Published: July 2024

This study provides an in-depth analysis of problems and policy proposals related to the Black Lives Matter (BLM) Movement in light of public administration (PA) theories. We examine the extant literature focusing on three PA paradigms: Classical, New Public Management (NPM), and Postmodernism (combined with New Public Administration—NPA). Based on a content analysis of BLM activists’ demands, Congressional bills, and resolutions, this study categorizes the problems and solutions according to the area of concern and PA paradigms. Results indicate that postmodern theories offer crucial lenses to understand BLM activists’ demands. However, Congressional bills and resolutions align more with Classical and NPM paradigms. We conclude that BLM policy proposals are more likely to be implemented if framed within NPM and “soft” postmodern perspectives. Similarly, policymakers and practitioners should know that the BLM movement reflects a postmodern approach. This study provides contributions that are relevant to both practitioners and academics.
The Second Founding: How the Civil War and Reconstruction Remade the Constitution
Authors: Brennemann Sheldon
Published: July 2024

By Eric Foner
New York: WW Norton & Company, 2019.
222 pages, hardcover.
Teachers Negotiating Professional Agency: A Socio-historical Study of the BElEd Programme
Authors: Sawhney Chhaya
Published: July 2024

"The link between education and sustainable livelihoods in this research gains importance specifically in the context of teachers and teacher education. This research captures the multiple journeys of Bachelor’s in Elementary Education (BElEd) alumni in an evolving socio-historical- educational context and policy frameworks. It collates individual narratives of the alumni to examine the curricular and pedagogic elements that characterise the BElEd programme. Specifically, it examines how students negotiate their professional and personal agency while doing the programme and its manifestations in their later career trajectories. The research offers both quantitative and qualitative insights into the successes and struggles of developing teachers as they navigate hierarchical school structures and contend with their increasingly marginalised role, status and identity within the larger policy discourse. Yet, there is a sense of hopefulness as they nurture self-reflexivity, experiment with new ideas and continue to work for social justice."
Impact of Self-Development on Developing Teachers
Authors: Gupta Monica
Published: July 2024

"This report shares the findings of a project seeking to document the diversity of formats, locales and processes involved in the implementation of the Self-Development curriculum across the eight colleges of Delhi University offering the BElEd programme. It also critically examines the influence of engaging with the Self Development Workshops (SDW) and the course on Human Relations and Communication (HRC) on the “agency” in the personal, professional and social lives of BElEd alumni and pre-service students from these eight colleges. The report further seeks to explore if reflective thinking and conscious development in SDW and HRC enable students in resisting regressive practices and in initiating democratic, equitable and collaborative practices in schools and personal life spaces."
Los controles en la contratación estatal de obra pública frente a la seguridad y salud en el trabajo
Authors: Restrepo Montoya Camilo Andrés , Mondragón Duarte Sergio Luis
Published: July 2024

Este artículo aborda elementos teóricos, legales y conceptuales acerca de los controles ejercidos desde la contratación estatal en temas de obra pública frente al Sistema de General de Seguridad Social Integral, en entidades públicas y privadas que establezcan relaciones negociales con el Estado, a fin de reducir los desequilibrios económicos y sociales que puedan originarse como producto de accidentes, incidentes, maternidad o desempleo. En el desarrollo del artículo se realizó una investigación cualitativa con un alcance analítico de revisión documental que permitió llegar a conclusiones generales en el campo de la sg-sst, a partir de premisas epistemológicas, dogmáticas y normativas con las que se constata que estos controles pueden garantizar la seguridad y la salud en el trabajo y la existencia y validez del contrato estatal.
Nanotherapeutics to cure inflammation-induced cancer
Authors: Kumar Rajiv
Published: July 2024

Aims: Nanotherapeutics are being explored as a potential solution to treat inflammation-induced cancer. Nanotherapeutics enhance innate immune cells' immunity, enabling them to fight tumors effectively. These cells secrete specific chemicals like cytokines, allowing them to replicate quickly and respond to future threats, making them suitable for immunotherapy.Methods: Nanotechnology can significantly improve human health by enhancing infection detection, prevention, and treatment. Nanomedicines, composed of restorative and imaging compounds in submicrometer-sized materials, aim to deliver effective treatments and limit inflammation in healthy body areas. Combining nanotechnology and clinical sciences, nanoparticles are suitable for gene therapy and have been developed for treating various diseases, including cancer, cardiovascular, diabetes, pulmonary, and inflammatory diseases.Results: Neutrophils and their offspring, including films and extracellular vehicles, are crucial drug transporters for enhanced growth therapy. Tumor microenvironment inputs can modify tumor-associated neutrophils (TANs), which are essential for tumor growth and healing. Human tumor intratumor heterogeneity is crucial for tumor growth and healing. Nanomedicines have shown potential in targeted delivery, toxicity reduction, and therapeutic effectiveness enhancement. However, clinical relevance and efficacy remain inadequate due to a lack of understanding of the interaction between nanomaterials, nanomedicine, and biology. The diverse biological milieu impacts the dynamic bioidentity of nanoformulations, and their interactions can modify therapeutic function or cellular absorption.Conclusion: Nanotechnology holds great promise for improving human health by detecting, preventing, and treating infections. Nanomedicines, a fusion of clinical sciences and nanotechnology, use submicrometer-sized transporter materials for therapy delivery and reducing contamination. Nanoparticles' small size and high surface-to-volume ratio can benefit gene therapy. Research has led to a wide range of nanomedicine products globally.
أثر استراتيجية التسريع المعرفي في تعلم بعض مهارات كره القدم الصالات
Authors: طه طلال فرحان عباس , ابراهيم عبد الرضا ندى
Published: July 2024

هدف البحث الى التعرف على أثر استراتيجية التسريع المعرفي في تعلم بعض المهارات الأساسية بكرة القدم الصالات واستخدم الباحثان المنهج والتجريبي بتصميم المجموعتين المتكافئتين ذات الاختبارين القبلي والبعدي اذ توصل الباحثان الى عدد من الاستنتاجات حيث ان هناك تأثير إيجابي جيد، لاستراتيجية التسريع المعرفي في تعلم المهارات (دقة المناولة، الإخماد، الدحرجة) , وأن الخطوات التي أتبعت وفق استراتيجية التسريع المعرفي كان دورها مميزاً في إضافة المعرفة وتوافر بيئة تعليمية للمتعلم جعلته يتقدم في أداء المهارات المختارة, وهناك تأثير إيجابي لاستراتيجية التسريع المعرفي في درس كرة القدم الصالات لدى المجموعة التجريبية أفضل من المجموعة الضابطة التي استخدمت الطريقة المتبعة في التفكير الجانبي والمعرفة القانونية وتعلم بعض المهارات في كره القدم صالات, وقد أوصى الباحثان الاهتمام باستخدام استراتيجيات تجعل المتعلم محورا أساسا في العملية التعليمية, ويجب إدخال وسائل حديثة تسهم في زيادة رغبة الطلاب في تعلم المهارات في كره القدم الصالات, ويجب توافر بيئة تسهم في تفاعل الطلاب وإشراكهم جميعا في أنشطة تزيد من أدائهم وتنمي التفكير العلمي لديهم.
The relationship between vertebral column flexibility and power of limbs with achievement in javelin
Authors: Khudhur mohammed Aram
Published: July 2024

In order to reach peak performance in any sport activity require preparations in terms of (physical, skills, plans, mentality and psychology) accordingly with the nature of the activity require scientific planning. Javelin throw is not beyond these preparations whereas power and flexibility contribute significantly in reaching peak level and advanced results. Power assists in throwing for further horizontal distance possible and flexibility in economy of performance energy. The researcher used descriptive correlational method on a sample of (15) male students of fourth grade whom intentionally selected, following test selection, experiment application, data collection and analyzing though the statistical package of social sciences (SPSS) the researcher concluded the there is a significant relationship between vertebral column flexibility and speed power of limbs with javelin throw achievement.
Simultaneously Adjusting Deployment Strategies for Mega-Constellations Using Low-Thrust Maneuvers
Authors: Pu Huang , Guangwei Wen , Zhaokui Wang
Published: July 2024

Deploying a constellation can be costly and inefficient. The ultimate goal is to position multiple satellites into designated orbital slots with the fewest launches and lowest energy consumption. This paper presents a method for simultaneous right ascension of the ascending node (RAAN) and argument of latitude (AOL) adjustments using continuous low thrust. Firstly, how changes in the semimajor axis and inclination affect the RAAN and the AOL is analyzed. A control method is proposed, and all satellites are sequentially placed from the injection orbit to the working orbit at specific time intervals. Because the RAAN and AOL are coupled with each other, a priority control strategy is introduced. This strategy ensures that the AOL is accurately satisfied within the time between each maneuver. Next, equations that correlate the RAAN and the AOL with the orbit inclination deviation and maneuver interval time are established. By studying the maneuver time intervals and inclination compensations, a highly accurate synchronized deployment scheme can be obtained. A simulation experiment based on the OneWeb constellation is carried out. In the simulation, 80 satellites are launched by just one rocket. By employing the proposed method, the constellation is successfully deployed. Results from the simulation verified the effectiveness of the proposed algorithm, which may be employed for rapid deployment of a mega-constellation in the future.
Philosophy and Art(history) Reconsidered
Authors: Raynova Yvanka
Published: July 2024

Editorial introduction to the first issue of Labyrinth 2020, which is dedicated to the general theme "Philosophy, Art(theory), and Literature."
Young woman with high fever and a massive rise in N-terminal pro-B-type natriuretic peptide (NT-pro-BNP)
Authors: Sundarka Manoj Kumar , Sundarka Archana , Lohani Krishna Kumar
Published: July 2024

A 33-year-old lady presented with acute symptoms suggestive of pneumonia. She rapidly deteriorated and needed intensive care unit care. She was found to have an enormous rise in N-terminal pro-B-type natriuretic peptide (NT-Pro-BNP), nearly in six digits without any previous co-morbidity. NT-Pro-BNP high levels could be reflective of cardiac injury, heart failure (HF), or chronic kidney disease (CKD), and a few other medical conditions. The final diagnosis was for acute on chronic kidney disease.
Stimulasi Perkembangan Aspek Kognitif Anak Usia Dini melalui Alat Permainan Edukatif
Authors: Ariani Ni Putu Ayu Dewi , Putra Ida Bagus Komang Sindu
Published: July 2024

Alat permainan edukatif merupakan alat yang digunakan tenaga pendidik untuk membantu proses belajar mengajar agar lebih bervariasi dan menyenangkan. Kiera Si Monyet Pintar merupakan alat permainan yang dibuat untuk membantu menstimulasi aspek perkembangan kognitif anak usia dini. Akan tetapi tidak semua anak memiliki kemampuan kognitif yang berkembang sesuai usianya. Penelitian ini bertujuan untuk mengetahui bagaimana meningkatkan aspek perkembangan kognitif anak usia dini guna untuk menstimulasi aspek perkembangan kognitif anak usia dini agar berkembang dengan baik.Metode yang di gunakan pada penelitian ini adalah pendekatan kualitatif. Subjek penelitian adalah guru-guru di TK Widya Dharma Sastra. Teknik pengumpulan data dengan wawancara dan Observasi. Hasil wawancara dan Observasi dianalisis dengan trianggulasi. Penelitian ini memperoleh hasil Kiera Si Monyet Pintar dapat menstimulasi aspek perkembangan kognitif anak usia dini. Alat permainan edukatif Kiera si Monyet Pintar efektif untuk digunakan dalam meningkatkan perkembangan kognitif pada anak
Pengenalan Bahasa Inggris untuk Anak Usia Dini
Authors: Rahayu Sucik , Wangsanata Susana Aditiya , Alivia Alivia , Muhimmatun Anisa
Published: July 2024

Pengenalan bahasa Inggris untuk anak usia dini penting karena globalisasi telah menjadikan bahasa Inggris sebagai bahasa internasional yang krusial dalam berbagai aspek kehidupan. Anak-anak memiliki kemampuan optimal untuk menyerap bahasa baru pada usia dini, sehingga pengenalan bahasa Inggris sejak awal dapat memberikan keuntungan jangka panjang. Pembelajaran bahasa asing pada usia dini juga dapat meningkatkan perkembangan kognitif dan pemahaman lintas budaya. Kajian ini perlu dilakukan untuk mengembangkan metode pengajaran yang efektif dan sesuai dengan tahap perkembangan anak, sehingga dapat memaksimalkan manfaat pembelajaran bahasa Inggris bagi anak usia dini. Penelitian ini bertujuan untuk mengeksplorasi dan menganalisis proses pengenalan bahasa Inggris untuk anak usia dini. Penelitian menggunakan pendekatan kualitatif. Pengumpulan data melalui observasi partisipatif, wawancara mendalam dengan guru dan orang tua, serta analisis dokumen kurikulum. Lokasi penelitian di RA Sunniyyah Selo Grobogan. Hasil penelitian ini diharapkan dapat memberikan wawasan berharga tentang strategi yang efektif dalam memperkenalkan bahasa Inggris kepada anak usia dini di lingkungan pendidikan Islam, serta memberikan rekomendasi praktis untuk pengembangan kurikulum dan metode pengajaran di RA Sunniyyah Selo Grobogan dan institusi serupa lainnya. Selain itu, penelitian ini berimplikasi pada peningkatan kesadaran akan pentingnya pengenalan bahasa Inggris sejak usia dini di lingkungan pendidikan anak usia dini, khususnya di RA Sunniyyah Selo Grobogan. Hasil penelitian juga dapat mendorong peningkatan kualitas dan kompetensi guru dalam mengajarkan bahasa Inggris kepada anak-anak usia dini di lembaga pendidikan serupa.
Freedom of speech and the right to information in gemeronyms of the periodical press of Yakutia (1887-1928)
Authors: Borisova N. M.
Published: July 2024

This article examines the connection of the gemeronyms of Yakut periodicals with cultural and historical phenomena, where the desire for freedom of speech and the right to information influenced the formation and dissemination of a democratic and national press in Yakutia. However, during the historical process, there was no stable media system during this period. Consequently, the press of Yakutia reflected the movement of the socio-political life of that time and depended on fluctuations in political power. The scientific novelty of the research lies in the fact that for the first time in Yakut journalism, an attempt was made to comprehend and systematise the names of newspapers and magazines as an independent unit, taking into account its functional specificity in communication processes. The purpose of the study is to determine the peculiarity of the reflection of freedom of speech and the right to information in the gemeronyms of newspapers and magazines in Yakutia in the pre–revolutionary period, after the February Revolution and during the period of liberalisation of Soviet power. The relevance of studying the gemeronym has become the basis for further research, which is due to its special role in the historiographical process as a whole. In our case, a distinctive feature of the media onomasticon is its interdisciplinarity. The study used methods of observation and content analysis of the hemeronyms of periodicals as onomastic realities. In addition, the method of retrospective analysis using "keywords" and "key meanings" is used to systematise the history of the Yakut periodical press.
Arctic Transport and Communication Initiative in the 21st century (using the Polar Silk Road Initiative as an example)
Authors: Zhai Ziming
Published: July 2024

The Arctic transport and communication initiative of the 21st century, with the Chinese idea of the «Polar Silk Road» as an example, is considered as a concept of peaceful coexistence within the framework of achieving the «Common Future» of the Sustainable Development Goals by 2030. The Arctic concept is presented using the world-political approach of N. K. Kharlampieva, which highlights the conceptual components of international relations development at the level of strategic planning of economic, transport and communication processes at the regional and global levels. This approach made it possible to build a strategic structure: a) to study the development of transport communication in the Arctic as a methodology; b) to describe the basis for the development of the Arctic transport and communication infrastructure. In the context of a tense foreign policy situation, it is particularly important to focus on the development of transport communication between China and Russia, where the achievement of the Sustainable Development Goals plays a special role in the development of the Arctic transport and communication infrastructure in the 21st century at the bilateral level.
Development of creative industries in the regions on the example of the Republic of Sakha (Yakutia)
Authors: Verkhovtseva M. A.
Published: July 2024

The paper examines the report of the chief economist of the Russian State Development Corporation Andrei Klepach «Why the population in the East is declining and what to do to combat this trend». Based on the competent analysis of the country’s chief economist, the regional state of the creative economy was examined with a focus on training and supporting students and young personnel for the creative industries. It is the creative industry that currently has the highest rate of youth involvement. Russia has all the necessary prerequisites for a dynamic pace of development of creative industries, as well as a number of successful examples of creative work not only in the central part of the country, but also in the regions. In 2019, the Government of the Republic of Sakha (Yakutia) approved the Concept for the development of the creative economy of the Republic of Sakha (Yakutia) until 2025, becoming the first subject of Russia where a strategic document on the development of the creative economy was adopted at the regional level. On April 27, 2024, the Decree «On the development of the creative economy of the Republic of Sakha (Yakutia)» was adopted. By 2030, it is planned to employ over 70 thousand Yakut citizens in the creative industries; new businesses will be created in science and education, information technology and cinema, design, art and architecture, with the subsequent commercialization of creative potential. The introduction of new educational programs adapted for the implementation of student projects and startups in the creative industries sector has a positive impact on the development of the creative sector of the economy.
An ecosystem approach to the development of a physically active population in the Arctic conditions
Authors: Kolodeznikova S. I. , Kolodeznikov R. S.
Published: July 2024

In the modern world, human well-being and his development determine the level of development of society as a whole. It is therefore important to focus efforts on creating conditions for every person to live a fulfilling life, including access to quality healthcare, education, cultural and sporting events. Investment in a person is necessary in order to ensure his successful participation in society, his self realization and the realization of potential. A healthy, educated and developed person is able to fully contribute to the development of society, improve the economy and social sphere. We must remember that man is the center of any ecosystem, and his well-being should be the main concern of society. Investment in people today is an investment in the future of society, which will bear fruit in the form of progress towards a more just and developed world. The idea is reflected that the well-being of a modern person depends, among other things, on his physical health. In this regard, an analysis of the development of physical culture is given using the example of the Arctic region, defined as part of the structure of the ecosystem of modern society. It talks about the need for a conscious approach to increasing the physically active population in the Arctic region.
Risks of operation of the Russian gas industry in the newest conditions
Authors: Kryukov Y. V.
Published: July 2024

The article analyzes the risks and limitations faced by the Russian gas industry in recent years. Russian gas sector faced with the negative influence of a number of internal and external factors («the perfect storm»). Currently, there is unprecedented pressure, that include not only falling export revenues, but also technological limitations. The Russian gas sector has been able to partially adapt to new operating conditions – a more flexible method of gas monetization is coming to the fore. Pipeline gas is increasingly losing its role as the basis for the development of the gas sector in the medium term, giving way to liquefied natural gas. The key factors limiting the operation of the industry are technological risks and restrictions in gas production and liquefied gas production, resource base limitations, risks on the side of the gas transportation system, as well as institutional risks and restrictions. In addition to development difficulties, new restrictions make it possible to reconsider the role of the gas sector in the economy: use more flexible approaches to export issues, develop domestic demand for gas, promote the development of independent gas production companies, and implement programs to support domestic manufacturers of a wide range of gas equipment and gas carriers.