bluuebunny/crossref_metadata_2025 huggingface dataset:
Nefropatia membranosa
Authors: Dantas Márcio , Silva Lázaro Bruno Borges , Pontes Barbhara Thaís Maciel , dos Reis Marlene Antônia , de Lima Patrícia Soares Nunes , Moysés Neto Miguel
Published: July 2023

RESUMO A nefropatia membranosa é uma glomerulopatia, cujo principal alvo acometido é o podócito, e acarreta consequências na membrana basal glomerular. Tem maior frequência em adultos, principalmente acima dos 50 anos. A apresentação clínica é a síndrome nefrótica, mas muitos casos podem evoluir com proteinúria não nefrótica assintomática. O mecanismo consiste na deposição de complexos imunes no espaço subepitelial da alça capilar glomerular com subsequente ativação do sistema do complemento. Grandes avanços na identificação de potenciais antígenos alvo têm ocorrido nos últimos vinte anos, e o principal é a proteína “M-type phospholipase-A2 receptor” (PLA2R) com o anticorpo anti-PLA2R circulante, o que possibilita avaliar a atividade e o prognóstico dessa nefropatia. Essa via de lesão corresponde aproximadamente a 70% a 80% dos casos da nefropatia membranosa caracterizada como primária. Nos últimos 10 anos vários outros antígenos alvo potenciais têm sido identificados. Esta revisão se propõe a apresentar de modo didático aspectos clínicos, etiopatogênicos e terapêuticos da nefropatia membranosa, incluídos os casos com ocorrência no transplante renal.
Passifloraceae s.s. da Ilha de São Luís, Estado do Maranhão, Brasil
Authors: Garcia Amanda Letícia , Silva Eduardo Oliveira , Ferreira Alessandro Wagner Coelho , Marinho Lucas Cardoso
Published: July 2023

RESUMO A Ilha de São Luís, Estado do Maranhão, configura-se como uma região ecotonal, um misto de floresta úmida, mata-de-cocais, vegetação de dunas, restingas e manguezais. Diferentemente do interior do Estado do Maranhão, suas zonas costeiras possuem uma lacuna sobre o conhecimento da família Passifloraceae. Aqui, por meio de expedições de campo e consulta a herbários, nós fornecemos o tratamento taxonômico, chave de identificação e comentários sobre as Passifloraceae da Ilha de São Luís. Foram registradas dez espécies: Passiflora auriculata Kunth, P. edulis Sims, P. foetida L., P. glandulosa Cav., P. laurifolia L., P. misera Kunth, P. nitida Kunth, P. picturata Ker Gawl., P. subrotunda Mast. e P. vespertilio L. As espécies P. picturata e P. misera foram registradas pela primeira vez na Ilha de São Luís.
The high prevalence of infectious diseases among health workers indicates the need for improving surveillance
Authors: Araújo Tânia Maria de , Souza Fernanda de Oliveira , Helioterio Margarete Costa , Andrade Kaio Vinicius Freitas de , Pinho Paloma de Sousa , Werneck Guilherme Loureiro
Published: July 2023

Abstract Objective: to estimate the seroprevalence of arboviruses, syphilis, HIV, and hepatitis B (HBV) in Healthcare Workers (HCW). Methods: a survey among HCW among was randomly selected in a city in Bahia-Brazil. The research used a structured questionnaire, which collected sociodemographic, occupational, and health information in 2019. Rapid immunochromatographic tests were used to track infections. Thus, positive results for arboviruses, syphilis, HIV, and HBV indicated seropositivity for the respective infection. In addition, simultaneous detection of antibodies for zika (ZIKV) and dengue (DENV) viruses indicated seropositivity for flavivirus infection. Results: a total of 453 HCW were included, 82.8% were women. Most HCW (55.1%) reported contact with biological material; 5.2% reported injuries with biological material. The seroprevalence was 34.7% (95%CI:30.1-39.4) for dengue, 1.7% (95%CI:0.7-3.4) for zika, 9.9% (95%CI:7.2-13.2) for chikungunya, and 39.9% (95%CI:35.2-44.7) for flavivirus (ZIKV+DENV); with 21.9% (95%CI:18.1-26.2) being negative to all arboviruses. Seropositivity to arboviruses increased with age and was higher among endemic disease control agents. Three HCW tested positive for HBV (HBsAg); no HIV cases were detected. Conclusion: a high percentage of HCW was exposed to infectious agents (contact with biological material and/or exposure to arboviruses). Among the necessary conditions for preventing infections in the work environment, the following stand out: monitoring of infectious diseases among HCW, surveillance of work environments, and measures to control occupational exposures, such as the availability of repellents.
Muscari seed germination enhancement by using sulfuric acid, and stratification priming
Authors: Labbaf Narjes , Rohollahi Iman , Naji Amir Mohammad
Published: July 2023

Abstract Muscari with absorbing color is a widespread and commercial species. As a pot and bedding bulb flower has excellent adaptability and vigorous growth in late winter and early spring. The quantity and uniformity of Muscari propagation by seed and the importance of seed priming will be measured in current experiment. The selected M. neglectum populations which already were gathered in our previews research and M. armeniacum were evaluated under separated sulfuric acid (5, 15, and 20 min) and hot water (5, 15, and 20 min) scarification plus 15, 30, and 45 days stratification in a completely randomized design, four replications were planted in separate containers. Seeds of M. armeniacum only germinate (70%) by 15 min sulfuric acid plus 45-day stratification treatments. Based on the analysis of variance and mean comparison data that only were reported in M. neglectum, their seeds optimally germinated by 5 and 15 min sulfuric acid treatment plus 45-day stratification. In conclusion, M. neglectum seeds germination is tuned to take place well in mid-winter under natural conditions; on the other hand, 45 days of lengthy constant stratification and 5 min sulfuric acid priming will accelerate M. neglectum seeds germination.
Morphological and molecular characterization of native Heliconia sp. accessions of the Amazon region
Authors: Krause Sarah , Krause Willian , Santos Eileen Azevedo , Rossi Ana Aparecida , Cordeiro Maria Helena Menezes , Silva Celice Alexandre
Published: July 2023

Abstract Heliconias are tropical plants with ornamental potential. These plants are particularly used in the floriculture industry because of their exotic colors and shapes. Species characterization is important for the selection of genotypes for the ornamental plant market and subsequent application in studies of genetic improvement. The aim of this study was to estimate the genetic divergence of Heliconia densiflora and Heliconia psittacorum accessions based on quantitative morphological and molecular markers. The morphological and molecular descriptors revealed genetic variability among the accessions evaluated. The greatest genetic variability was observed among H. psittacorum accessions, whose sample number was also larger compared to H. densiflora. Morphological characterization was efficient in differentiating the two Heliconia species, especially to characteristics such as bract and inflorescence length, postharvest durability, and flower stem diameter, which contributed most to the divergence in this study. On the other hand, molecular characterization identified one H. densiflora individual that was grouped with the H. psittacorum genotypes. The results showed that ISSR markers can differentiate closely related H. densiflora and H. psittacorum individuals. The materials evaluated can contribute to the maintenance of local genetic diversity through the germplasm bank of the local breeding program of ornamental tropical plants.
Weber e Tolstói: aproximações
Authors: Gigante Lucas Cid
Published: July 2023

Resumo A produção literária de Goethe, Dostoiévski e Tolstói, para citar apenas alguns nomes, está presente na elaboração intelectual de vários pensadores da passagem do século XIX para o século XX, como Freud e Marx. Para Weber não é diferente. Neste trabalho, pretendemos explorar algumas obras de Tolstói para reunir pontos de notável convergência com o pensamento weberiano. Mais do que fornecedor de metáforas ou ilustrações, Tolstói nos permite uma ampliação do campo de visão em que Weber expõe alguns de seus importantes momentos conceituais, como o desencantamento do mundo, ou reflexões teóricas de fundo, como a irracionalidade ética do mundo e os conceitos de racionalidade e racionalização, bem como as relações entre a ação humana e a história. Buscamos aproximar esses momentos teóricos de Weber com a obra ficcional de Tolstói, indicando pontualmente uma triangulação com Goethe e Dostoiévski. Tal aproximação faz da literatura um local de grande importância para a consideração teórica ou, pelo menos, permite um aprofundamento da elaboração e da exposição desta em seus conceitos.
Do final rehabilitation volumes influence function after anterior cross ligament reconstruction? A pilot study
Authors: Souza Rafaela Maria de , Tiburcio Afonso de Mello , Claudio Ana Carolina de Jacomo , Micheletti Jéssica Kirsch , Menossi Berlis Ribeiro dos Santos
Published: July 2023

Abstract Introduction Rupture of the anterior cruciate ligament (ACL) is one of the frequent traumatic injuries of the knee joint complex, and the isokinetic dynamometer is essential to assess and measure its joint function. Objective To analyze the volume of physical therapy treatment using the same protocol with different duration in patients undergoing ACL reconstruction. Methods This is a prospective observational cohort study. The sample consisted of 13 adult male individuals who underwent ACL reconstruction surgery. Participants were divided into two groups: accelerated treatment (AC) and non-accelerated treatment (NAC). Participants underwent a standardized protocol of post-reconstruction physio-therapy, starting in the immediate postoperative period. The AC group performed the treatment three times a week, with a duration of 4 hours each session for 6 months, while the NAC performed twice a week with duration of two hours each session for eight months. Results The groups showed the same behavior during the post-reconstruction treatment periods, showing that regardless of time, the results were beneficial at the end of the treatment. However, in the accelerated protocol, the injured limb showed a significant difference for extender peak torque (PTEXT) in the preoperative and 4-month postoperative period (230.5 vs 182.6), 4-month postoperative period and final (182.6 vs 242.1) in the AC group, while in the NAC group there was no significant difference between times in this same limb. Conclusion Greater volumes of weekly training characterized better results, showing that rehabilitation time is not a predictor of discharge, but rehabilitation time obtains good results for the variables.
Death and life in the abortion debate: an analysis based on the public hearing on ADPF 442
Authors: Rybka Larissa Nadine , Cabral Cristiane da Silva
Published: July 2023

Abstract Starting from the premise that the agenda on reproductive rights is home to political disputes in the field of sexuality and reproduction, this article reviews the debate held at the public hearing on the Argument of Noncompliance with a Fundamental Precept (Arguição de Descumprimento de Preceito Fundamental, ADPF) # 442 in August 2018. The lawsuit proposes the decriminalization of abortion induced by the pregnant woman herself or with her consent until the 12th week of gestation. At the hearing convened by the Supreme Court, 50 amicus curiae presentations were held, catalyzing the current arguments raised in the public debate on abortion in Brazil. The content of the public hearing (characters, places, images, audios, texts, and video) is taken as empirical material for this research. Considering the centrality of the defense of life/combating death argument, both in speeches for and against the ADPF, we examine the different frameworks used by political actors on the scene when debating the issue of abortion in terms of a clash between death and life. More than a polysemy, it is a clash that makes explicit hierarchies regarding reproduction and women’s lives.
A fertility citizenship - women’s health policies as technologies of sex and gender production
Authors: Rosa Hevelyn , Cabral Cristiane da Silva
Published: July 2023

Abstract This article analyzes how the main public policies on Brazilian women’s health, since 2000, define and characterize their target group. Marking an articulation between different sets of agents, disciplinary fields, and government technologies, public policies operate by representing and conforming the subject to whom they are intended. In women’s health field, this process is also made possible by modulating sex and gender, specifically reiterating codes responsible for designating the “nature” of women. This is a documentary research conducted via the anthropological perspective of documents analysis, which investigated the documentary pieces of the Política Nacional de Atenção Integral à Saúde da Mulher (2004) and Rede Cegonha (2011) and related documents. The themes of fertility and reproduction have been persistent in the set of actions in women’s health, making up the core areas that concentrate state efforts and funds. The woman embraced by health policies has greater chances of accessing her citizenship rights from her role as a potential reproducer. The complex construction of a subject of rights is identified, even when this construction was imbued with a certain emancipatory ideology, in the interstices of the State.
Degradation of pharmaceuticals in sanitary effluent by the combination of oxidation and photo-oxidation processes
Authors: Bisognin Ramiro , Wolff Delmira B. , Carissimi Elvis , Prestes Osmar Damian , Zanella Renato
Published: July 2023

Abstract Most conventional sewage treatment systems are not able to fully remove micropollutants found in sewage. Thus, the simultaneous degradation of 11 pharmaceuticals identified in the effluent of a sewage treatment plant in Southern Brazil was herein investigated through advanced oxidation processes based on ozonation, ultraviolet radiation and hydrogen peroxide. For detection, samples were prepared through solid-phase extraction and pharmaceuticals were identified through ultra-high performance liquid chromatography tandem mass spectrometry. Active ingredients such as ciprofloxacin, oxytetracycline, paracetamol, sulfamethoxazole and trimethoprim had their concentrations increased for degradation analysis purposes. Trials were carried out on a bench at room temperature and neutral pH, with aliquots collected at 7.5 and 15 minutes. Two ozone doses (0.5 and 0.9 mg per mg of dissolved organic carbon), and combinations of the lowest ozone dose with photolysis (254 nm) and with 25 mg.L−1 of hydrogen peroxide were evaluated. Pharmaceuticals mineralization efficiency was assessed in a total organic carbon analyzer. The process combining ozone, hydrogen peroxide and ultraviolet radiation was the most efficient in the degradation of all pharmaceuticals detected in this study, since it enabled reducing oxytetracycline by 89.32%, caffeine by 96.79%, trimethoprim by 97.40%, ciprofloxacin by 97.75%, sulfamethoxazole by 99.79%, paracetamol by 99.96%, and clindamycin, ofloxacin, sulfadiazine, sulfathiazole and tylosin by 100%. This process also recorded the highest mineralization rate (60.52%), fact that confirmed the potential to decrease persistent pharmaceuticals found in conventional sewage treatment systems.
Cartography of solid waste management in Southern Bahia, Brazil
Authors: da Silva Marconi Vieira , Zanchi Fabricio Berton , Lopes Elfany Reis do Nascimento
Published: July 2023

Abstract Although the Brazilian Solid Waste Policy is in force, cities continue to face difficulties in complying with it, thus perpetuating negative environmental impacts caused by solid waste. This study analyzed, from a cartographic perspective, the deficits and the implications of inadequate urban solid waste management in an area of the Brazilian northeast. A questionnaire structured in 3 sections and 26 questions (management of public cleaning services, waste collection, and solid waste disposal) was applied to eight managers of the municipal agencies responsible for solid waste areas. The quality index of landfills was applied, and the gravimetric characterization of solid waste was performed by the technique of quartering and segregation of waste in visits to the disposal sites of each city. It was identified that 75% of the cities do not have hierarchical strategies for prevention, reduction, reuse, recycling, and adequate treatment of urban solid waste, with insufficient budget. Only one city collects throughout its perimeter, and the waste collected is destined to open dumps considered inadequate or of low quality. The waste mass is composed, on average, of 50% organics, 20% rejects, 15% plastics, and 9% paper and cardboard. The recent Brazil sanitation regulation can be a way to reduce the aggravation and regularize the collection, transportation, and disposal of solid waste.
El sueño de la crítica produce monstruos: Educación en disputa, entre libertad y barbarie
Authors: Brugnaro Júnior Maurício
Published: July 2023

Resumen El estudio se enfoca en la educación secundaria integrada brasileña (como un tipo ideal) – principalmente en el período actual con avances neoliberales que buscan la reificación del ser –, incluye factores que apoyan la implementación del modelo de esta educación e identifica dos aspectos del concepto que se desarrollan en libertad o barbarie, el depende de sus premisas y de los intereses sociales establecidos por los agentes implicados. Así, busca establecer el campo educativo como disputa entre diferentes hegemonías sociales. Los materiales utilizados están basados en bibliografías que abordan el tema educativo en relación con la sociedad en su práctica de emancipación y están recogidos críticamente en libros y artículos científicos, caracterizados como un debate teórico, pero que se fundamenta sobre prácticas y métodos de la realidad material. Los resultados confirman la hipótesis del campo educativo en disputa, también argumentan que la educación secundaria integrada corresponde a los intereses de la clase ya hegemónica, pero que no es algo establecido, pues está en disputa, encontrándose en los agentes sociales, como educadores y estudiantes, y en la unión de clases, el movimiento por la una posible educación liberadora. Así, se confirma que donde no hay crítica, aparecen los monstruos, tal como aquí se los entiende. El estudio significa una extensión del debate educativo, se reconoce como una línea de estudio y no busca cerrar la discusión, sino ampliarla, proporcionando la ubicación de conceptos para que sea posible identificar fuerzas fundamentales para las orientaciones sociales, políticas públicas y praxis de la vida cotidiana.
Intervenção em raciocínio quantitativo como possibilidade para o desenvolvimento do conhecimento aritmético
Authors: Nogues Camila Peres , França Akira Borba Colen , Dorneles Beatriz Vargas
Published: July 2023

Resumo O baixo desempenho em habilidades matemáticas no início da vida escolar pode acarretar problemas de aprendizagem a longo prazo. Por isso, destaca-se a importância de se conhecer as habilidades matemáticas básicas que influenciam a aprendizagem especificamente da aritmética para, com isso, ser possível indicar intervenções focadas em habilidades preditoras do desempenho nessa área e auxiliar tanto o desenvolvimento do conhecimento matemático dos estudantes quanto a prática dos professores. Nesse sentido, o objetivo deste estudo foi investigar os efeitos de uma intervenção em raciocínio quantitativo no desempenho aritmético de estudantes de 4º e 5º anos do ensino fundamental. Para isso, quarenta crianças foram separadas nos grupos experimental e controle. O grupo experimental participou de um programa de intervenção com foco no raciocínio quantitativo, organizado em sete sessões, duas vezes por semana e com duração de 45 minutos cada sessão, enquanto o grupo controle participou de sessões envolvendo jogos matemáticos e práticas de mindfulness. Os resultados indicaram que não houve efeito significativo da intervenção quando comparados os desempenhos entre os grupos. Entretanto, foi encontrada uma melhora significativa especificamente no desempenho dos alunos de 5º ano que participaram do grupo experimental. Os achados do presente estudo contribuem para a compreensão de princípios instrucionais eficazes e destacam a importância das práticas de ensino serem baseadas em evidências.
Perspectiva de género en actitudes hacia la probabilidad y su enseñanza en futuro profesorado chileno
Authors: Ruz Felipe , Berciano Alcaraz Ainhoa , Martínez-Ortiz Francisco , Contreras García José M.
Published: July 2023

Resumen Considerando que la promoción de una disposición positiva hacia la probabilidad y la estadística se ha establecido como una de las metas prioritarias de la corriente reformista en torno a su enseñanza en la escuela, en este trabajo, se adopta una perspectiva de género para abordar el objetivo de analizar las actitudes hacia la probabilidad y su enseñanza en una muestra de 269 futuros profesores y profesoras de matemática de Chile. A través de una metodología cuantitativa y con un alcance descriptivo, se identifican diferencias estadísticas entre las actitudes declaradas por las participantes y los participantes según la perspectiva teórica asumida. Los resultados reflejan en general actitudes positivas tanto en las futuras profesoras como en los futuros profesores. Sin embargo, las actitudes fueron significativamente más positivas en el grupo de hombres en lo referido a sus sentimientos de agrado hacia la probabilidad y la tendencia a usar el contenido para resolver problemas cuando sea conveniente. Se concluye con la discusión de las metas propuestas en contraste con la literatura previa y se proyectan los hallazgos como un insumo para considerar aspectos afectivos en la formación inicial del profesorado responsable de enseñar probabilidad en la escuela al igual que la inclusión de la perspectiva de género de modo transversal en dicho proceso.
Adaptation of students who started higher education during remote teaching in Minas Gerais
Authors: Domingues Sérgio , Souza Rita de Cássia de , Melo Carolina Silva Bandeira de , Cruz Beatriz Monteiro da
Published: July 2023

Abstract This article presents a study performed in early 2022 with 186 students who started higher education at a federal university and in a private college – both in the countryside of Minas Gerais – during the remote teaching period, that is, 2020 and 2021. The research was carried out remotely by emailing a form to all participants and having an online discussion with two of them. The questionnaire consisted of questions about the students’ profile, their experiences during remote teaching, as well as of the reduced version of the Academic Experience Questionnaire – QVA-r, which aims to investigate the students’ experiences and adaptation to higher education. The data showed that students’ interpersonal relationships were affected by remote teaching. As for the personal dimension, measured by the QVA-R and related to mental health and wellbeing, it was severely impaired, which can be an effect of social distancing caused by the Covid-19 pandemic. On the other hand, it was surprising to observe how students and the educational institutions themselves developed ways of becoming close - not only in class but also extra-classroom - by using information and communication technologies to have relationships, even from a distance. The results also show that students considered that their learning had been negatively affected by remote teaching, and that, despite it being easy and convenient, they were eager for better learning with the return of face-to-face classes.
A adaptação de estudantes que chegaram à educação superior em Minas Gerais durante o ensino remoto
Authors: Domingues Sérgio , Souza Rita de Cássia de , Melo Carolina Silva Bandeira de , Cruz Beatriz Monteiro da
Published: July 2023

Resumo Este artigo apresenta uma pesquisa desenvolvida no início de 2022, com 186 estudantes que ingressaram no ensino superior durante o período remoto, ou seja, 2020 e 2021, em uma universidade federal e em uma faculdade particular, ambas do interior de Minas Gerais. A pesquisa foi realizada de maneira remota com o envio de um formulário por e-mail e a realização de uma roda de conversa online com duas estudantes. O questionário continha perguntas sobre o perfil dos estudantes, suas experiências no ensino remoto e o Questionário de Vivências Acadêmicas reduzido – QVA-r que tem por objetivo investigar as vivências e a adaptação de estudantes ao ensino superior. Os dados mostraram que as relações interpessoais dos estudantes foram afetadas pelo ensino remoto e a dimensão pessoal, medida pelo QVA-r e relacionada com a saúde mental e bem-estar, estava bastante prejudicada, o que pode ser um efeito do distanciamento social provocado pela pandemia do Covid-19. Por outro lado, surpreendeu o quanto os estudantes e as próprias instituições de ensino criaram meios de aproximação, tanto intra quanto extraclasse, utilizando as tecnologias de informação e comunicação para criar conexões, mesmo à distância. Os resultados mostram, ainda, que os estudantes consideravam que a aprendizagem tinha sido prejudicada pelo ensino remoto e que, apesar de suas facilidades e comodidade, estavam ansiosos por uma melhor aprendizagem com o retorno das aulas presenciais.
Agreement between measured weight, height and BMI and Web-based self-reported data in participants of the 1993 Pelotas Birth Cohort, Brazil: a cross-sectional validation study
Authors: Botelho Vivian Hernandez , Barros Aluísio J. D. , Oliveira Renata Gonçalves de , Martins Rafaela Costa , Gonçalves Helen , Menezes Ana M. B. , Blumenberg Cauane
Published: July 2023

ABSTRACT Objective: to evaluate the agreement between measured height, weight, and body mass index (BMI) during the 22-year follow-up of the 1993 Pelotas Birth Cohort, state of Rio Grande do Sul, Brazil, and self-reported data during the online follow-up of the coortesnaweb. Methods: this was a cross-sectional validation study; agreement was assessed by means of Lin’s concordance correlation coefficient for continuous measures and weighted Kappa for nutritional status; Spearman’s rank correlation coefficient was used to estimate the correlation between measurements. Results: a total of 783 participants were included; it could be seen high correlation and high agreement between the measured height (r = 0.966; ρ = 0.966), weight (r = 0.934; ρ = 0.928), and BMI (r = 0.903; ρ = 0.910) and Web-based self-reported data; there was no correlation between mean difference and the time interval between measurements. Conclusion: using the Internet to collect self-reported anthropometric measurements is as valid as the traditional method.
Environmental impacts of landfills: perspectives on bio-monitoring
Authors: Vaverková Magdalena Daria , Paleologos Evan K , Goli Venkata Siva Naga Sai , Koda Eugeniusz , Mohammad Arif , Podlasek Anna , Winkler Jan , Jakimiuk Aleksandra , Černý Martin , Singh Devendra Narain
Published: July 2023

Environmental regulations on landfills contain detailed instructions for monitoring the impacts of pollution from leachate on water, air and soil. However, references to the impact of landfills on the landscape and the need to monitor the surrounding vegetation are described only in general terms. Studies have indicated that near-surface pollution events, which are not necessarily captured by existing regulatory monitoring schemes, have affected the vegetation in the vicinity of landfills. Indications for the effects of pollution emanating from landfills include the retreat of sensitive and native plant species, the abundance of halophytes or nitrophilous plants and the prevalence of other invasive plant species, which can spread to adjacent ecosystems. To the best of the authors’ knowledge, a comprehensive synthesis of landfill plant-based biomonitoring results has not yet been reported. The advantage of biomonitoring lies in its ability to assess the quality of the environment as perceived by living organisms. This would facilitate the determination of the response of plants to departures from natural conditions, detection of trends occurring in ecosystems and adoption of management practices to prevent or mitigate degradation of the environment. Thus, to detect such effects on the flora surrounding a landfill, this paper recommends that biomonitoring be utilised in environmental regulations to complement existing monitoring techniques.
Examination of Placental Dysfunction and Neonatal Outcomes in Hospitalized Patients who have Hyperemesis Gravidarum Diagnosis
Authors: ERİÇ HORASANLI Jule , ŞENGÜL Nurullah
Published: July 2023

Background: Evidence on the effect of hyperemesis gravidarum (HG) on pregnancy outcomes is still unclear. In this study, placenta-related dysfunctions and neonatal outcomes in patients who were hospitalized with HG were retrospectively analyzed.

Methods: This study was conducted retrospectively among women who had singleton deliveries in our hospital between January 2015 and January 2020. As the case group, women with singleton pregnancies who were hospitalized due to HG and delivered were included. The control group consisted of women with singleton pregnancies who delivered without hospitalization due to HG. Through the hospitalization files of the patients who were hospitalized due to HG and not hospitalized due to HG, neonatal outcomes such as placental dysfunction, including gestational diabetes, gestational hypertension, preeclampsia, or stillbirth, and low birth weight, small for gestational age (SGA), preterm birth (PTB), the necessity for neonatal intensive care, 5-min Apgar scores, were examined.

Findings: The mean gestational age was determined as 37.7 ± 1.5 weeks in the HG group and 37.8 ± 1.4 weeks in the control group. The mean week of gestation upon hospitalization for HG was 10.6 ± 3.6 weeks. There was no significant difference between the groups regarding preeclampsia, PTB, postpartum hemorrhage, birth weight, GDM, or neonatal intensive care unit requirement. It was found that SGA babies with abnormal birth weights were seen more frequently in the deliveries of patients hospitalized for HG (P = 0.022). The 5-min Apgar scores were higher in the deliveries of patients hospitalized for HG than in the control group (P = 0.004).

Conclusion: It was concluded that hospitalizations due to HG do not pose a risk of placental dysfunction. Of the neonatal outcomes, SGA was more common in the infants of mothers with HG. Contrary to the expectations herein, the 5-min Apgar scores were higher in hospitalized patients for HG.
Lymphadenopathies associated with Cat-Scratch Disease in Turkiye
Authors: YAHŞİ Aysun , YAZICIOĞLU Bahadır
Published: July 2023

Aim: Bartonella henselae is the etiologic agent of cat-scratch disease. The disease affects children and young adults. The objective of this study is to analyze the epidemiology, clinical features, and course of this disease in Turkiye.

Materials and Methods: Children without immunodeficiency, with relevant clinical signs and symptoms, and positive serology were included in the study. Clinical, demographic and laboratory data of patients diagnosed with cat-scratch disease between October 2018 and February 2021 were evaluated retrospectively.

Results: A total of 46 patients were included. The mean age was 132 months (IQR 90- 153 months), and 69.6% (n = 32) were male. There was a history of cat contact in 73.9% of the patients and 43.5% of these were with household cats. Most of the lymphadenopathies were axillary (73.9%), and generalized lymphadenopathy was not observed. The median duration of symptoms before admission was 4 weeks. The median ultrasonographic lymphadenopathy size was 4 cm. The median clinical improvement time was 6.5 weeks. Azithromycin was given in 18 patients and intravenous and/or oral beta-lactamase inhibitor combination therapy in 18 patients while no treatment was necessary in 10 patients.

Conclusion: The typical presentation is a solitary, enlarged lymph node, mostly in the axillary region. Bartonella henselae IgG level should be studied prior to invasive procedures. It should be known that cat scratch disease can develop without a history of cat contact. Meanwhile, it should be known that contact with a house cat may cause disease more often than contact with street cats.
Changes in the ubiquitination system in children with cerebral palsy
Authors: DOĞAN Ayşe Gülşen , ÇETİN İhsan
Published: July 2023

Objective: We aimed to investigate the levels of Ubiquitin Carboxy Terminal Hydrolase-L1 enzyme (UHC-L1), Transactive Response DNA Binding Protein-43 (TDP-43) and Cullin-3 in peripheral blood associated with ubiquitination processes in children with cerebral palsy (CP).

Materials and Methods: We included 50 children with CP in the first patient group. In the control group, there were 30 healthy children who were matched with the patient groups in terms of age and gender. We also recorded risk factors for CP, CP type, botox application, orthosis use, maternal age at birth, and additional problems. Patients aged 6-10 years, diagnosed with CP, without genetic, metabolic disease or mental retardation history were included in this study.

Results: There were 32 female and 18 male patients in the CP group, while there were 19 female and 11 male volunteers in the control group. Maternal age was significantly higher in the CP group (p=0.002). In our study, as a result of the comparison between the control group and the CP group in terms of UCH-L1, TDP-43 and Cullin 3 levels; the levels of UCH-L1 (p=0.048), TDP-43 (p=0.028) and Cullin 3 (p=0.042) in the CP group were found to be statistically significantly lower than the levels of the control group.

Conclusion: The low serum concentrations of UCHL-L1, Cullin 3 and TDP-43 molecules in the CP group and the statistically positive correlation of these molecules with each other may help to understand the neuronal pathophysiology after disruption of the ubiquitination system.
Relationship Between Prolonged Jaundice and Vitamin B12 Levels in Term Newborn
Authors: YALINBAŞ Emine Esin , DURMAZ Yaşar , MUTLU Fezan
Published: July 2023

Abstract

Aim: Vitamin B12 deficiency, when observed during the neonatal period, can generally be traced back to maternal causes. In cases of vitamin B12 deficiency, hyperbilirubinemia may occur due to hem overproduction as the result of erythrocyte lysis. Prolonged jaundice is common during the neonatal period, and its underlying etiological causes should be analyzed. The aim of this study was to analyze whether vitamin B12 deficiency has any effect on prolonged jaundice formation in infants.

Material and Method: The study examined 89 infants; this included 45 that had been diagnosed with prolonged jaundice and 44 in the control group. Their clinical and demographic characteristics were recorded. Patient group was formed with term infants with prolonged jaundice excluding possible etiological causes of prolonged jaundice. Both the maternal and infant vitamin B12 levels were analyzed.

Results:An indirect bilirubin level of 11.8 mg/dl in the prolonged jaundice group and 3.16 mg/dl (p < 0.001), a hemoglobin level of 14.18 gr/dl and 15.7 gr/dl (p = 0.005), and infant vitamin B12 level of 168 pg/ml and 205.2 pg/ml (p=0.013) in the patient and control groups, respectively, showed significant differences between the two. Maternal vitamin B12 levels were found to be similar in the patient and control groups (p= 0.315), and there was no significant correlation between the vitamin B12 levels of the infants and mothers (r = 0.278, p = 0.064).

Conclusion: Vitamin B12 deficiency can be related to prolonged jaundice in neonatals, and an early diagnosis of vitamin B12 deficiency in high risks group in the neonatal period can be useful in terms of potentially identifying and controlling related conditions.

Keywords: Jaundice, newborn, vitamin B12 deficiency
ASSOCIATION OF TOLL-LIKE RECEPTOR 9 EXPRESSION WITH PROGNOSIS IN BREAST CARCINOMA
Authors: ÇELİK Zeliha Esin , DEMİR Fatih , YONAR Harun , ÇELİK Murat , EREN Orhan Önder
Published: July 2023

Aim:

Breast cancer (BC) is a common malignancy in women. Some molecules including TLR9 are still under investigation as potential prognostic factors in BC. In the present study, we aimed to determine the relation between TLR9 expression and clinicopathological prognostic parameters and survival in BC.

Materials and methods:

One hundred and thirty nine patients diagnosed as BC included the present study. Immuno-reactivity scoring (IRS) system was used to reveal the tissue TLR9 expression levels.

Results:

We found higher TLR9 expression in tumors diagnosed as invasive carcinoma NOS, grade 3 tumors, tumors with necrosis, ER negative and Her2 positive tumors and tripple negative molecular subtype. Furthermore, tumors with low TLR9 scores showed increased overall survival compared to tumors with high TLR9 scores.

Conclusions:

TLR9 overexpression in BC is associated with some prognostic parameters including histologic type, tumor grade, tumor necrosis, ER and Her2 status and molecular subtype as well as overall survival. Further studies with larger patient series are needed to shed light on the use of TLR9 as a clinical and therapeutic target in BC.
Influence of technological parameters during multiwire cutting of GaAs ingots on the surface characteristics of the plates
Authors: Podgorny D. A. , Nestyurkin M. S. , Komarovskiy N. Yu.
Published: July 2023

Mechanical processing of semiconductor monocrystalline ingots is one of the key stages in the production of GaAs wafers. The main issue for obtaining high-quality plates is to determine the optimal parameters of machining and is to identify the dependencies of the surface quality of the substrates after cutting on the parameters set in this technological process. Technology for the production of polished semiconductor wafers (substrates) almost all semiconductor materials have a similar and has in its difference only a number of distinctive features related to the mechanical and structural features of individual materials. Mechanical processing is the first stage after crystal growth, in which it is necessary to observe and improve many technological parameters to obtain high-quality finished products. In the technological process of semiconductor processing, it is necessary first of all to divide the crystal into plates with similar surface characteristics. The quality of this separation determines which plates will eventually turn out and how suitable they will be as substrates for the production of devices in mass production. The study of the influence of cutting parameters on the structure of the disturbed layer and the basic geometric parameters of the plates allows us to identify the optimal parameters of mechanical cutting and to identify the range of deviations possible to obtain plates of similar quality for further processing.
Thermal and thermoelectric properties of zinc oxide ceramics alloyed with metals
Authors: Pashkevich A. V. , Fedotov A. K. , Poddenezhny E. N. , Bliznyuk L. A. , Khovaylo V. V. , Fedotova V. V. , Kharchanko A. A.
Published: July 2023

The paper studies the thermal, electrical and thermoelectric properties of ZnO–MexOy ceramics with 1 ≤ x, y ≤ 3, where Me = Al, Co, Fe, Ni, Ti. The samples were made on the basis of ceramic sintering technology of powder mixtures of two or more oxides in an open atmosphere with variations in temperature and duration of annealing. Structural and phase studies of ceramics indicate that the addition of powders of MexOy alloying agents to ZnO powder with a wurtzite structure after the synthesis process leads to the release of secondary phases such as Znx(Me)yO4 spinels and a 4-fold increase in the porosity of the resulting ceramics. Studies of thermal conductivity at room temperature indicate the predominance of the lattice contribution. The decrease in thermal conductivity during doping is due to an increase in phonon scattering due to the influence of the following factors: (1) the size factor when replacing zinc ions in the ZnO (wurtzite) crystal lattice with metal ions from the added MexOy oxides; (2) the formation of defects – point, grain boundaries (microstructure grinding); (3) increase in porosity (decrease in density); and (4) formation of additional phase particles (such as spinels Znx(Mе)yO4). The effect of these factors in the substitution of zinc ions with metals (Co, Al, Ti, Ni, Fe) leads to an increase in the thermoelectric Q-factor of ZT by 4 orders of magnitude (due to a decrease in electrical resistivity and thermal conductivity with a relatively small decrease in the coefficient of thermal EMF). The reason for the decrease in electrical resistance is the more uniform redistribution of alloying metal ions in the wurtzite lattice, resulting in an increase in the number of donor centers, formed with an increase in the duration of annealing.
María Reguera
Authors:   dehistoria. Cultura. Historia. Patrimonio
Published: July 2023

Activista a prol da universalidade da educación
María Mazás Lata
Authors: Armesto María
Published: July 2023

Non se pinta senón a imposibilidade de pintar. Esta é a miña conciencia. María MazásEn plena madurez creativa, despois de residir en Barcelona entre 1984 e 2013, agás tres anos que viviu en Alemaña, María Mazás volve a Galicia para instalarse na casa familiar da Coruña e habilitar alí o que ía ser o seu derradeiro taller. Un fermoso espazo comunicado cun patio-terraza que a artista converte nunha particular horta-xardín, bosque animado en que conflúen atlántico, mediterráneo e zen, fornecendo de luz o laboratorio en que creará a súa derradeira e conmovedora obra.
Assessing the performance of techniques for disaggregating daily rainfall in South Africa
Authors: R Ramlall  , JC Smithers
Published: July 2023

Design flood estimation (DFE) methods are used to limit the risk of failure and ensure the safe design of hydrological and related infrastructure, and to inform water resources management. In order to improve DFE methods which are based on event or continuous simulation rainfall–runoff models, it is generally necessary to use sub-daily rainfall data. However, sub-daily rainfall gauges are relatively sparse and have shorter record lengths than daily rainfall gauges in South Africa. Rainfall temporal disaggregation (RTD) techniques can be used to produce finer resolution data from coarser resolution daily rainfall data. Several RTD approaches have been developed and are used in South Africa. However, there is a need to review and assess the performance of the available RTD methods. This paper contains an overview of selected RTD approaches and the performance of the methods at selected sites in South Africa, for disaggregating daily rainfall into 15-min intervals. Temporal distributions of rainfall were represented by dimensionless Huff curves, which served as the basis for comparison of observed and disaggregated rainfall. In a pilot study it was found that the SCS-SA (Soil Conservation Service model South Africa) distributions and the Knoesen model approaches performed considerably better than the other approaches. The RTD approaches were further assessed using data from 14 additional rainfall stations. For the additional stations, the Knoesen model and SCS-SA disaggregated rainfall generally provided the most realistic temporal distributions.
Investigating the knowledge gap in research on climate and land use change impacts on water resources, with a focus on groundwater resources in South Africa: a bibliometric analysis
Authors: Monica M Correia  , Thokozani Kanyerere  , Nebo Jovanovic  , Jaqueline Goldin
Published: July 2023

Climate and land use change (CLUC) impact studies on water and groundwater resources have evolved in recent years. To determine whether all research gaps have been or are being addressed through the current intellectual structure, a bibliometric analysis, as well as a record review, was enacted to determine the intellectual structure of CLUC impacts on water resources, with a particular focus on the implications for groundwater resources research in the Breede Gouritz Water Management Area (BGWMA) in South Africa. Methods applied included publication-related trends and science mapping. This study found that CLUC impact research being published has increased by 600% between 2014 and 2021, localised research is being done in 95 countries, and land use change (LUC), specifically urbanisation, is being considered more often as a variable. However, a few gaps in the research remain, including smaller spatiotemporal scales in more locations, a stronger focus on LUC in all its forms, LUC versus climate change (CC) impact studies, and multi-modal approaches to related research. CLUC impacts on water and groundwater resources research have made significant progress over the years, but more research is necessary to make this a robust area of research.
Multiple linear regression models for the estimation of water flows for forest management and planning in Türkiye
Authors: Hayati Zengin  , Mehmet Özcan  , Ahmet Salih Değermenci  , Tarık Çitgez
Published: July 2023

While there are many factors, including climatology, geography, topography, vegetation and soil, that affect hydrologic processes, understanding the role of forests seems most essential, due to their manageable nature. In this study, a holistic approach was taken, and possible factors affecting streamflow, including tree, sapling, shrub, herb and soil strata, were measured for 29 small catchments/stream basins located in Turkey. Linear regression models were developed in order to estimate water flow (m³‧ha−1). Several models were suggested for use in practice. These models were based on the data on hand and displayed a sufficient level of explained variance in the dependent variable. Model 5, based on the variablesof catchment area (ha), drainage density, ratio of coniferous stand areas in the catchment (%), tree volume (m³‧ha−1), leaf area index, number of short saplings (number‧ha−1), and topsoil sand rate (%), was recommended for flow estimation, achieving a 0.73 adjR² value for test data. These variables can be obtained as part of a survey and water managers can use them to estimate water flow of the catchment. The generated models can be used in multiple-use planning of forests, e.g. in adjusting the volume of stands to get optimum benefit from wood and water production. One of the most interesting results and one that was opposite to that documented in the general literature, was the positive correlation between tree volume and flow per hectare, which suggests a strategy of growing older tree stands to enable greater water production.