bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables S1-S4 from Downregulated miR329 and miR410 Promote the Proliferation and Invasion of Oral Squamous Cell Carcinoma by Targeting Wnt-7b
Authors: Shiah Shine-Gwo , Hsiao Jenn-Ren , Chang Wei-Min , Chen Ya-Wen , Jin Ying-Tai , Wong Tung-Yiu , Huang Jehn-Shyun , Tsai Sen-Tien , Hsu Yuan-Ming , Chou Sung-Tau , Yen Yi-Chen , Jiang Shih Sheng , Shieh Yi-Shing , Chang I-Shou , Hsiao Michael , Chang Jang-Yang
Published: March 2023

Supplementary Tables S1-S4. Supplementary Table S1: Clinicopathological characteristics of 40 pairs of OSCC specimens and their corresponding non-tumorous epithelia. Supplementary Table S2: A list of deregulated miRNA in 40 pairs of OSCC specimens and their corresponding non-tumorous epithelia. Supplementary Table S3: Characteristics of 83 OSCC patients for Wnt-7b IHC study. Supplementary Table S4: Top ten of enriched transcriptional factors in miRNA overexpression.
Data Supplement from IL4 Receptor ILR4α Regulates Metastatic Colonization by Mammary Tumors through Multiple Signaling Pathways
Authors: Venmar Katherine T. , Carter Kathy J. , Hwang Daniel G. , Dozier E. Ashley , Fingleton Barbara
Published: March 2023

Expanded methods description
Data Supplement from A Novel Wnt Regulatory Axis in Endometrioid Endometrial Cancer
Authors: Zhao Yu , Yang Yihua , Trovik Jone , Sun Kun , Zhou Liang , Jiang Peiyong , Lau Tat-San , Hoivik Erling A. , Salvesen Helga B. , Sun Hao , Wang Huating
Published: March 2023

Supplemental Figures S1-S6. Promoter CpG methylation of PCDH10 in EEC samples (S1); PCDH10 inhibits EEC cell proliferation and induces cell apoptosis (S2); Genome-wide analysis of PCDH10 induced transcriptomic changes by RNAseq (S3); PCDH10 inhibits MALAT1 transcription through Wnt/β-catenin signaling (S4); PCDH10 expression decreases nuclear β-catenin level in HEC1-B cells (S5); MALAT1 expression in EEC tumors (S6).
Data Supplement from A Novel Wnt Regulatory Axis in Endometrioid Endometrial Cancer
Authors: Zhao Yu , Yang Yihua , Trovik Jone , Sun Kun , Zhou Liang , Jiang Peiyong , Lau Tat-San , Hoivik Erling A. , Salvesen Helga B. , Sun Hao , Wang Huating
Published: March 2023

Supplemental Methods and References. Description of additional methods and procedures used in the study. Also includes Supplemental References.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: March 2023

Supplementary Figure S1. Chemical structure of afatinib and cytotoxicity effect of afatinib on various cell lines that used in this study.
Supplemental Methods, Figure Legends from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: March 2023

Supplemental Methods, Supplemental Figure legends Figure S1, Figure S2, Figure S3, Figure S4, Figure S5, Figure S6, Figure S7
Supplementary Figure 6 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: March 2023

PDF file - 44K, The expression of miR-22 in breast cancer tissues.
Data Supplement from AMPK Reverses the Mesenchymal Phenotype of Cancer Cells by Targeting the Akt–MDM2–Foxo3a Signaling Axis
Authors: Chou Chih-Chien , Lee Kuen-Haur , Lai I-Lu , Wang Dasheng , Mo Xiaokui , Kulp Samuel K. , Shapiro Charles L. , Chen Ching-Shih
Published: March 2023

Table S1
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: March 2023

Fig. S1. Supplementary data for large scale genomic aberrations illustrated in Figure 2, including: A) the distribution of mapped read density of WGS; B) PCR confirmation of translocation and fusion junctions of a superamplicon; and C) PCR and RT-PCR amplification of MGAM, ZFAND3, and the ZFAND3-MGAM fusion gene. Fig. S2. The distribution of mapped read density of WES, supplementary data for Figure 3. Fig. S3. Differentially expressed genes and functions among complex, simple carcinomas and normal mammary glands, supplementary data for Figure 3. Fig. S4. IHC images of histone modifications in canine normal mammary glands at 400X magnification, supplementary data for Figure 4. Fig. S5. IHC images of histone modifications in simple carcinomas, complex carcinomas and normal mammary glands at 200X magnification, supplementary data for Figure 5. Fig. S6. Supplementary data for homology between canine MCs and human breast cancers described in Figure 6. These include differentially expressed genes between ER+ and ER- carcinomas at FDR â‰¤ 0.1 and an example of PAM50 clustering indicating canine and human tumor IDs.
Data Supplement from Molecular Homology and Difference between Spontaneous Canine Mammary Cancer and Human Breast Cancer
Authors: Liu Deli , Xiong Huan , Ellis Angela E. , Northrup Nicole C. , Rodriguez Carlos O. , O'Regan Ruth M. , Dalton Stephen , Zhao Shaying
Published: March 2023

Supplementary Table S2. Supplementary data for CNA discovery in canine MCs by aCGH and WGS analyses, including CNA result summary, amplified/deleted gene list and chimeric sequence reads related to the superamplicon.
Supplementary Methods and Supplementary Figure 1-20 from SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGFβ Signals That Increase Expression of VEGF-C
Authors: Liu Dan , Li Li , Zhang Xiao-Xue , Wan Dong-Yi , Xi Bi-Xin , Hu Zheng , Ding Wen-Cheng , Zhu Da , Wang Xiao-Li , Wang Wei , Feng Zuo-Hua , Wang Hui , Ma Ding , Gao Qing-Lei
Published: March 2023

Supplementary Methods and Supplementary Figure 1-20: Supplementary Figure 1 shows the growth of the tumors after orthotopic transplantation. Supplementary Figure 2 shows that over-expression of SIX1 promotes lymphangiogenesis and lymph-node metastasis of C33a cells in vivo. Supplementary Figure 3 shows the assay of cytokine and growth factor with antibody-based array. Supplementary Figure 4 shows the expression of the genes coding for the lymphangiogenic factors. Supplementary Figure 5 shows that SIX1 promotes VEGF-C expression in C33a cells. Supplementary Figure 6 shows that SIX1 promotes migration and tube-formation of HLECs. Supplementary Figure 7 shows the knock-down of VEGF-C in cervical cancer cells. Supplementary Figure 8 shows that the promotional effect of SIX1-expressing tumor cells on the migration and tube-formation of HLECs in vitro is mediated by VEGF-C. Supplementary Figure 9 shows that the promotional effect of SIX1-expressing tumor cells on lymphangiogenesis in vivo is mediated by VEGF-C. Supplementary Figure 10 shows that the promotional effect of SIX1-expressing C33a cells on lymphatic-vessel is mediated by VEGF-C. Supplementary Figure 11 shows that the promotional effect of SIX1 on lymph-node metastasis in vivo is mediated by VEGF-C. Supplementary Figure 12 shows the differences in gene expression levels between tumors in vivo and tumor cells cultured in vitro. Supplementary Figure 13 shows the immunohistochemical analysis of TGF-βs in tissue microarray of human CSCC specimens. Supplementary Figure 14 shows that SIX1 enhances the effect of TGF-β1 on VEGF-C production by tumor cells and tube-formation of HLECs in vitro. Supplementary Figure 15 shows that TGF-β contributes to the differences in VEGF-C expression between tumors in vivo and tumor cells cultured in vitro. Supplementary Figure 16 shows that TGF-β signaling is required for SIX1 to promote lymphangiogenesis and lymph-node metastasis in vivo. Supplementary Figure 17 shows that knocking down the expression of SMAD2 or SMAD3 or TβR1 suppresses TGF-β1 induced VEGF-C expression. Supplementary Figure 18 shows that higher expression of SIX1 correlates with higher expression of TβR1 in human CSCC specimens. Supplementary Figure 19 shows the binding of SIX1 to the VEGF-C promoter. Supplementary Figure 20 shows that knocking down the expression of SMAD2 and SMAD3 does not affect the binding of SIX1 to the VEGF-C promoter.
Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia
Authors: Čermáková Kateřina , Tesina Petr , Demeulemeester Jonas , El Ashkar Sara , Méreau Hélène , Schwaller Juerg , Řezáčová Pavlína , Veverka Vaclav , De Rijck Jan
Published: March 2023

Supplementary Figures S1-S9. Published structure of the MLL-MENIN-LEDGF/p75 complex (S1); Characterization of the murine MLL-AF9 AML model (S2); Coomassie stained SDS-PAGE gels of recombinant proteins used in this study (S3); Identification of the MLL-LEDGF/p75 interaction surface (S4); Protein melting curves of LEDGF/p75 mutants (S5); Model of the MLL-MENIN-LEDGF/p75 ternary interface (S6); Representation of the buried surface area of IBD amino acid residues upon binding either MLL or HIV-1 integrase (S7); A MLL interaction deficient LEDGF/p75 mutant cannot rescue MLL-AF9 transformation upon LEDGF/p75 knockdown (S8); CP65 interferes with LEDGF/p75-MLL but not with MENIN-MLL complex formation in vitro (S9).
Supplementary Table 1 from Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling
Authors: Lapeire Lore , Hendrix An , Lambein Kathleen , Van Bockstal Mieke , Braems Geert , Van Den Broecke Rudy , Limame Ridha , Mestdagh Pieter , Vandesompele Jo , Vanhove Christian , Maynard Dawn , Lehuédé Camille , Muller Catherine , Valet Philippe , Gespach Christian P. , Bracke Marc , Cocquyt Veronique , Denys Hannelore , De Wever Olivier
Published: March 2023

MUC: mucoid carcinoma, IDCA: invasive ductal carcinoma, LOB: lobular carcinoma, I-NST: invasive, non special type, Max diam: maximal diameter, ER: estrogen receptor, PR: progesterone receptor, Pos LN: positive lymph nodes, BMI: body mass index.
Data Supplement from Trim32 Facilitates Degradation of MYCN on Spindle Poles and Induces Asymmetric Cell Division in Human Neuroblastoma Cells
Authors: Izumi Hideki , Kaneko Yasuhiko
Published: March 2023

Supplementary Figure S4. A GSK-3 inhibitor IX (BIO) suppresses spindle pole localization of MYCN under MG132 treatment. Percent of TGW (left) or SK-N-DZ (left) cells with MYCN accumulation to spindle poles. Error bars represent SEM from three experiments, P<0.0001 for TGW and P=0.006 for SK-N-DZ.
Supplementary Table 4 from Activated d16HER2 Homodimers and SRC Kinase Mediate Optimal Efficacy for Trastuzumab
Authors: Castagnoli Lorenzo , Iezzi Manuela , Ghedini Gaia C. , Ciravolo Valentina , Marzano Giulia , Lamolinara Alessia , Zappasodi Roberta , Gasparini Patrizia , Campiglio Manuela , Amici Augusto , Chiodoni Claudia , Palladini Arianna , Lollini Pier Luigi , Triulzi Tiziana , Menard Sylvie , Nanni Patrizia , Tagliabue Elda , Pupa Serenella M.
Published: March 2023

List of cases of the GSE 55348.
Supplementary Methods, Tables 1 - 2, Figures 1 - 8 from Targeting EphA3 Inhibits Cancer Growth by Disrupting the Tumor Stromal Microenvironment
Authors: Vail Mary E. , Murone Carmel , Tan April , Hii Linda , Abebe Degu , Janes Peter W. , Lee Fook-Thean , Baer Mark , Palath Varghese , Bebbington Christopher , Yarranton Geoffrey , Llerena Carmen , Garic Slavisa , Abramson David , Cartwright Glenn , Scott Andrew M. , Lackmann Martin
Published: March 2023

Methods: List of Antibodies, reagents and cell lines Table S1: Distribution of EphA3 protein in human cancers assessed by IHC. Table S2: Kinetic properties of mouse IIIA4 and chimeric IIIA4 for binding to EphA3 Figure S1: Expression patterns of EphA3 in human cancer tissue samples and cell lines. Figure S2: EphA3 is not expressed in normal adult mouse tissues and cell lines. Figure S3: Tumour targeting characteristics of the chIIIA4 antibody. Figure S4: chIIIA4 accumulation into tumour xenografts and association with [FITC] lectin-stained tumour vessels. Figure S5: The EphA3+ stromal tumour infiltrate contains a BM-derived cell population with mesenchymal stromal cell surface phenotype. Figure S6: Bone-marrow origin of EphA3+ tumour stromal cells. Figure S7: EphA3+ MSC's are not exposed to tumour endogenous ephrins; their activation with pre-clustered chIIIA4 triggers cell contraction and apoptosis. Figure S8: cIIIA4 antibody treatment-effects in PCa tumours.
Data Supplement from Molecular Imaging with Bioluminescence and PET Reveals Viral Oncolysis Kinetics and Tumor Viability
Authors: Kuruppu Darshini , Brownell Anna-Liisa , Shah Khalid , Mahmood Umar , Tanabe Kenneth K.
Published: March 2023

Supplemental Figure 1: Tumor growth imaged with Rluc bioluminescence correlates with volumetric measurements from caliper readings. S1A: 4T1-Rluc tumor growth imaged with Rluc bioluminescence. The area of Rluc expression in the bilateral flank tumors increased over time. S1B: The Rluc signal intensities (expressed as mean net intensity/area +/- SD) increased, corresponding to tumor volume (expressed as the mean +/- SD) obtained with caliper measurements.
Supplementary Table S1 from Phosphoinositide Protein Kinase PDPK1 Is a Crucial Cell Signaling Mediator in Multiple Myeloma
Authors: Chinen Yoshiaki , Kuroda Junya , Shimura Yuji , Nagoshi Hisao , Kiyota Miki , Yamamoto-Sugitani Mio , Mizutani Shinsuke , Sakamoto Natsumi , Ri Masaki , Kawata Eri , Kobayashi Tsutomu , Matsumoto Yosuke , Horiike Shigeo , Iida Shinsuke , Taniwaki Masafumi
Published: March 2023

Supplementary Table S1. Clinical information of patients whose myeloma cells were subjected to Western blotting and in vitro treatment with BX-912.
Supplementary Table S4 from Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer
Authors: Mouradov Dmitri , Sloggett Clare , Jorissen Robert N. , Love Christopher G. , Li Shan , Burgess Antony W. , Arango Diego , Strausberg Robert L. , Buchanan Daniel , Wormald Samuel , O'Connor Liam , Wilding Jennifer L. , Bicknell David , Tomlinson Ian P.M. , Bodmer Walter F. , Mariadason John M. , Sieber Oliver M.
Published: March 2023

Comparison of POLE mutation spectra between 9 NSHP and 15 non-NSHP CRC cell lines and TCGA-analyzed primary cancers.
Supplementary Table S3 from GPx2 Suppression of H2O2 Stress Links the Formation of Differentiated Tumor Mass to Metastatic Capacity in Colorectal Cancer
Authors: Emmink Benjamin L. , Laoukili Jamila , Kipp Anna P. , Koster Jan , Govaert Klaas M. , Fatrai Szabolcs , Verheem Andre , Steller Ernst J.A. , Brigelius-Flohé Regina , Jimenez Connie R. , Borel Rinkes Inne H.M. , Kranenburg Onno
Published: March 2023

Supplementary Table S3. The GPx2 co-expression signature.
Supplemental Figures 1-5 and Supplemental methods from Definition of Smad3 Phosphorylation Events That Affect Malignant and Metastatic Behaviors in Breast Cancer Cells
Authors: Bae Eunjin , Sato Misako , Kim Ran-Ju , Kwak Mi-Kyung , Naka Kazuhito , Gim Jungsoo , Kadota Mitsutaka , Tang Binwu , Flanders Kathleen C. , Kim Tae-Aug , Leem Sun-Hee , Park Taesung , Liu Fang , Wakefield Lalage M. , Kim Seong-Jin , Ooshima Akira
Published: March 2023

Supplemental Figures 1-5 and Supplemental Methods. Supplementary Figure 1. Blockade of Smad3 phosphorylation at the C-terminal and linker region by infection with adenoviral Smad3 mutants. Supplementary Figure 2. Mutation of the Smad3 linker phosphorylation sites enhances the TGF-β1-induced growth arrest and apoptosis. Supplementary Figure 3. Smad3 linker phosphorylation suppresses Smad3 transcriptional activity. Supplementary Figure 4. Mutation of Smad3 linker phosphorylation sites promotes the TGF-β-induced EMT and invasive activity. Supplementary Figure 5. Mutation of the Smad3 linker phosphorylation sites significantly inhibits the expression of embryonic transcription factors, mammosphere formation, and colony formation on soft agar.
Supplementary Figure S2 from GPx2 Suppression of H2O2 Stress Links the Formation of Differentiated Tumor Mass to Metastatic Capacity in Colorectal Cancer
Authors: Emmink Benjamin L. , Laoukili Jamila , Kipp Anna P. , Koster Jan , Govaert Klaas M. , Fatrai Szabolcs , Verheem Andre , Steller Ernst J.A. , Brigelius-Flohé Regina , Jimenez Connie R. , Borel Rinkes Inne H.M. , Kranenburg Onno
Published: March 2023

Supplementary Figure S2. Loss of GPx2 impairs differentiation of CSCs.
Data Supplement from HSV-sr39TK Positron Emission Tomography and Suicide Gene Elimination of Human Hematopoietic Stem Cells and Their Progeny in Humanized Mice
Authors: Gschweng Eric H. , McCracken Melissa N. , Kaufman Michael L. , Ho Michelle , Hollis Roger P. , Wang Xiaoyan , Saini Navdeep , Koya Richard C. , Chodon Thinle , Ribas Antoni , Witte Owen N. , Kohn Donald B.
Published: March 2023

Supplemental Figures S1-S3. Validation of sr39TK function in Jurkat cells (S1); ROI Analysis (S2); Chimerism, vector marking, and PET probe signal in vertebrae (S3).
Supplemental Fig. 6 from Pancreatic Cancer–Specific Cell Death Induced In Vivo by Cytoplasmic-Delivered Polyinosine–Polycytidylic Acid
Authors: Bhoopathi Praveen , Quinn Bridget A. , Gui Qin , Shen Xue-Ning , Grossman Steven R. , Das Swadesh K. , Sarkar Devanand , Fisher Paul B. , Emdad Luni
Published: March 2023

Supplemental Fig. 6. Effect of over-expression of AKT on [pIC]PEI-induced apoptosis
Supplementary Methods from Adaptive Responses to Dasatinib-Treated Lung Squamous Cell Cancer Cells Harboring DDR2 Mutations
Authors: Bai Yun , Kim Jae-Young , Watters January M. , Fang Bin , Kinose Fumi , Song Lanxi , Koomen John M. , Teer Jamie K. , Fisher Kate , Chen Yian Ann , Rix Uwe , Haura Eric B.
Published: March 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplementary Table 1 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: March 2023

Supplementary Table 1: Primers for Semi-quantitative RT-PCR
Supplementary Figure 4 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: March 2023

Supplementary Figure 4: Human PAD2 expression, along with Mouse Pad1, Pad2, Pad3, and Pad4 expression levels in transgenic mice
Supplementary Figure 3 from PAD2 Overexpression in Transgenic Mice Promotes Spontaneous Skin Neoplasia
Authors: McElwee John L. , Mohanan Sunish , Horibata Sachi , Sams Kelly L. , Anguish Lynne J. , McLean Dalton , Cvitaš Iva , Wakshlag Joseph J. , Coonrod Scott A.
Published: March 2023

Supplementary Figure 3: Expression of markers for inflammation and EMT across three tissues from MMTV-FLAG-PAD2 transgenic founder lines
Supplementary Materials and Methods from CD38-Expressing Myeloid-Derived Suppressor Cells Promote Tumor Growth in a Murine Model of Esophageal Cancer
Authors: Karakasheva Tatiana A. , Waldron Todd J. , Eruslanov Evgeniy , Kim Sang-Bae , Lee Ju-Seog , O'Brien Shaun , Hicks Philip D. , Basu Devraj , Singhal Sunil , Malavasi Fabio , Rustgi Anil K.
Published: March 2023

Supplementary materials and methods
Supplementary experimental procedures figure legends and references from Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance
Authors: Gurden Mark D. , Westwood Isaac M. , Faisal Amir , Naud Sébastien , Cheung Kwai-Ming J. , McAndrew Craig , Wood Amy , Schmitt Jessica , Boxall Kathy , Mak Grace , Workman Paul , Burke Rosemary , Hoelder Swen , Blagg Julian , Van Montfort Rob L.M. , Linardopoulos Spiros
Published: March 2023

Description of the supplementary experimental procedures figure legends and references
Supplementary Table S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Authors: Faria Claudia C. , Golbourn Brian J. , Dubuc Adrian M. , Remke Marc , Diaz Roberto J. , Agnihotri Sameer , Luck Amanda , Sabha Nesrin , Olsen Samantha , Wu Xiaochong , Garzia Livia , Ramaswamy Vijay , Mack Stephen C. , Wang Xin , Leadley Michael , Reynaud Denis , Ermini Leonardo , Post Martin , Northcott Paul A. , Pfister Stefan M. , Croul Sidney E. , Kool Marcel , Korshunov Andrey , Smith Christian A. , Taylor Michael D. , Rutka James T.
Published: March 2023

Supplementary Table S1. Foretinib concentrations in mouse brain, mouse plasma and the brain-plasma ratio
Supplemental Figures S1-S5 from Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling
Authors: Roy Ishan , McAllister Donna M. , Gorse Egal , Dixon Kate , Piper Clinton T. , Zimmerman Noah P. , Getschman Anthony E. , Tsai Susan , Engle Dannielle D. , Evans Douglas B. , Volkman Brian F. , Kalyanaraman Balaraman , Dwinell Michael B.
Published: March 2023

Representative time plot of oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) measurements & migratory and AMPK phosphorylation response to CXCL12 of patient-derived pancreatic cancer cells ; Characterization of murine-derived pancreatic cancer cells ; CXCL12-induced AMPK activity is Gαi and CXCR4 dependent ; CXCL12-induced AMPK activity is calcium dependent ; Cytostatic CXCL12 stimulates MYPT1 phosphorylation at T853 .
Supplementary Figure Legends from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis
Authors: Mumblat Yelena , Kessler Ofra , Ilan Neta , Neufeld Gera
Published: March 2023

Supplementary Figure Legends. Contains the figure legends for supplementary figures 1S to 7S.
Supplemental Movie 1 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis
Authors: Mumblat Yelena , Kessler Ofra , Ilan Neta , Neufeld Gera
Published: March 2023

Supplemental Movie 1. A time lapse movie of proliferating human umbilical vein derived endothelial cells (HUVEC)
Supplementary Figure S7 from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: March 2023

Supplementary Figure S7. TCGA colorectal cancer database analysis on selected targets.
Metabolomics Data from Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
Authors: Kamphorst Jurre J. , Nofal Michel , Commisso Cosimo , Hackett Sean R. , Lu Wenyun , Grabocka Elda , Vander Heiden Matthew G. , Miller George , Drebin Jeffrey A. , Bar-Sagi Dafna , Thompson Craig B. , Rabinowitz Joshua D.
Published: March 2023

Supplemental data. Human metabolomics data (raw and processed peak intensities and lists of samples and metabolites).
Supplementary Fig. S6 from Combining miR-10b–Targeted Nanotherapy with Low-Dose Doxorubicin Elicits Durable Regressions of Metastatic Breast Cancer
Authors: Yoo Byunghee , Kavishwar Amol , Ross Alana , Wang Ping , Tabassum Doris P. , Polyak Kornelia , Barteneva Natalia , Petkova Victoria , Pantazopoulos Pamela , Tena Aseda , Moore Anna , Medarova Zdravka
Published: March 2023

Supplementary Fig. S6. Gross anatomical features of mice treated with MN-anti-miR10b and doxorubicin.
Supplementary Figure S7 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: March 2023

Supplementary Figure S7. miR-135 and miR-203 reduce breast cancer metastasis to lung.
Supplementary Table and Figure Legends from Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer
Authors: Peng Jin , Hamanishi Junzo , Matsumura Noriomi , Abiko Kaoru , Murat Kumuruz , Baba Tsukasa , Yamaguchi Ken , Horikawa Naoki , Hosoe Yuko , Murphy Susan K. , Konishi Ikuo , Mandai Masaki
Published: March 2023

Legends for Supplementary Tables S1-S4 and Supplementary Figures S1-S22.
Supplementary Methods and Reference from Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer
Authors: Peng Jin , Hamanishi Junzo , Matsumura Noriomi , Abiko Kaoru , Murat Kumuruz , Baba Tsukasa , Yamaguchi Ken , Horikawa Naoki , Hosoe Yuko , Murphy Susan K. , Konishi Ikuo , Mandai Masaki
Published: March 2023

Description of additional methods and procedures used in the study. Also includes Supplementary Reference.
Supplementary Figure S2 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: March 2023

Supplementary Figure S2. Runx2 and Runx2-targeting miRNAs are regulated in metastatic breast cancer cells and bone metastases.
Supplemental Table S5 from Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Authors: Neskey David M. , Osman Abdullah A. , Ow Thomas J. , Katsonis Panagiotis , McDonald Thomas , Hicks Stephanie C. , Hsu Teng-Kuei , Pickering Curtis R. , Ward Alexandra , Patel Ameeta , Yordy John S. , Skinner Heath D. , Giri Uma , Sano Daisuke , Story Michael D. , Beadle Beth M. , El-Naggar Adel K. , Kies Merrill S. , William William N. , Caulin Carlos , Frederick Mitchell , Kimmel Marek , Myers Jeffrey N. , Lichtarge Olivier
Published: March 2023

Supplemental Table S5. Stratification of TP53 mutations by either disruptive or truncating systems in the training set did not identify a subset of mutations with decreased overall survival.
Supplemental Table S1 from Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
Authors: Neskey David M. , Osman Abdullah A. , Ow Thomas J. , Katsonis Panagiotis , McDonald Thomas , Hicks Stephanie C. , Hsu Teng-Kuei , Pickering Curtis R. , Ward Alexandra , Patel Ameeta , Yordy John S. , Skinner Heath D. , Giri Uma , Sano Daisuke , Story Michael D. , Beadle Beth M. , El-Naggar Adel K. , Kies Merrill S. , William William N. , Caulin Carlos , Frederick Mitchell , Kimmel Marek , Myers Jeffrey N. , Lichtarge Olivier
Published: March 2023

Supplemental Table S1. Summary of patient data and prognostic data for both the test and validation datasets.
Supplementary Methods, Tables 1 - 3, Figure Legend from HOXB7 Promotes Malignant Progression by Activating the TGFβ Signaling Pathway
Authors: Liu Shou , Jin Kideok , Hui Yvonne , Fu Jie , Jie Chunfa , Feng Sheng , Reisman David , Wang Qian , Fan Daping , Sukumar Saraswati , Chen Hexin
Published: March 2023

Table S1. The clinicopathological characteristics of clinical samples. Table S2. Primer sequences used in the cloning and quantitative PCR analysis. Table S3. Primer sequences used for the CHIP assay.
Supplementary Table 4 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: March 2023

List of SNPs successfully genotypes in the NCI/MD Case Control study.
Supplementary Table S3 from Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
Authors: Mazzocca Antonio , Dituri Francesco , De Santis Flavia , Filannino Addolorata , Lopane Chiara , Betz Regina C. , Li Ying-Yi , Mukaida Naofumi , Winter Peter , Tortorella Cosimo , Giannelli Gianluigi , Sabbà Carlo
Published: March 2023

Grouped genes according to their functions (analysis for comparative cellular processes) using the publicly available software ToppCluster multiple gene analyzer.
Supplementary Methods from Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
Authors: Mazzocca Antonio , Dituri Francesco , De Santis Flavia , Filannino Addolorata , Lopane Chiara , Betz Regina C. , Li Ying-Yi , Mukaida Naofumi , Winter Peter , Tortorella Cosimo , Giannelli Gianluigi , Sabbà Carlo
Published: March 2023

Description of additional methods and procedures used in the study.
Supplementary Table 2 from PI3K–mTORC2 but not PI3K–mTORC1 Regulates Transcription of HIF2A/EPAS1 and Vascularization in Neuroblastoma
Authors: Mohlin Sofie , Hamidian Arash , von Stedingk Kristoffer , Bridges Esther , Wigerup Caroline , Bexell Daniel , Påhlman Sven
Published: March 2023

Supplementary Table 2. Nucleotide sequences of primers used for qPCR reactions.
Supplementary Figure Legends and Table Legends from Targeting LUNX Inhibits Non–Small Cell Lung Cancer Growth and Metastasis
Authors: Zheng Xiaohu , Cheng Min , Fu Binqing , Fan Xiaolei , Wang Qing , Yu Xiaoqing , Sun Rui , Tian Zhigang , Wei Haiming
Published: March 2023

Supplementary Figure Legends
Supplementary Figure S2 from Genetic and Pharmacologic Inhibition of eIF4E Reduces Breast Cancer Cell Migration, Invasion, and Metastasis
Authors: Pettersson Filippa , del Rincon Sonia V. , Emond Audrey , Huor Bonnie , Ngan Elaine , Ng Jonathan , Dobocan Monica C. , Siegel Peter M. , Miller Wilson H.
Published: March 2023

Supplementary Figure S2. Ribavirin suppresses tumor growth in a human xenograft model.
Supplementary Figure S1 from Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner
Authors: Prabhu Varun V. , Allen Joshua E. , Dicker David T. , El-Deiry Wafik S.
Published: March 2023

Representative flow cytometry images for CD133 and CD44 TRAIL staining.
Supplementary Figure S4 from miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src
Authors: Shi Xu-Bao , Ma Ai-Hong , Xue Lingru , Li Meimei , Nguyen Hao G. , Yang Joy C. , Tepper Clifford G. , Gandour-Edwards Regina , Evans Christopher P. , Kung Hsing-Jien , deVere White Ralph W.
Published: March 2023

Function assay of AR variant's constitutive activity in yeast.
Supplemental Figure Legend from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: March 2023

Supplemental Figure Legend. Legend for Supplemental Figures S1-S7.
Supplementary Figure S1 from Constitutive Activation of Myosin-Dependent Contractility Sensitizes Glioma Tumor-Initiating Cells to Mechanical Inputs and Reduces Tissue Invasion
Authors: Wong Sophie Y. , Ulrich Theresa A. , Deleyrolle Loic P. , MacKay Joanna L. , Lin Jung-Ming G. , Martuscello Regina T. , Jundi Musa A. , Reynolds Brent A. , Kumar Sanjay
Published: March 2023

Supplementary Figure S1. Lack of serum does not render continuous GBM cell line U373-MG insensitive to matrix stiffness.
Supplemental Figure S5 from Generation of a Mouse Model of Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System through Combined Deletion of Snf5 and p53
Authors: Ng Jessica M.Y. , Martinez Daniel , Marsh Eric D. , Zhang Zhe , Rappaport Eric , Santi Mariarita , Curran Tom
Published: March 2023

Gene Set Enrichment Analysis shows close resemblance between human and mouse brain tumors.
Supplementary Figures from CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
Authors: Yoshida Taku , Kim Jee Hyun , Carver Kristopher , Su Ying , Weremowicz Stanislawa , Mulvey Laura , Yamamoto Shoji , Brennan Cameron , Mei Shenglin , Long Henry , Yao Jun , Polyak Kornelia
Published: March 2023

Supplementary Figures S1-S4: Supplementary Figure S1. CLK2 copy number and gene expression in breast cancer. Supplementary Figure S2. Validation of shRNA screen results for CLK2. Supplementary Figure S3. EMT-related changes following downregulation of CLK2. Supplementary Figure S4. Identification of breast tumor subtype-specific splice variants regulated by CLK2.
Supplementary Figure S4 from Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial
Authors: Erdem-Eraslan Lale , van den Bent Martin J. , Hoogstrate Youri , Naz-Khan Hina , Stubbs Andrew , van der Spek Peter , Böttcher René , Gao Ya , de Wit Maurice , Taal Walter , Oosterkamp Hendrika M. , Walenkamp Annemiek , Beerepoot Laurens V. , Hanse Monique C.J. , Buter Jan , Honkoop Aafke H. , van der Holt Bronno , Vernhout René M. , Smitt Peter A.E. Sillevis , Kros Johan M. , French Pim J.
Published: March 2023

Survival of patients included in the Belob trial stratified by molecular subtype.
Supplementary Figure S1 from Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial
Authors: Erdem-Eraslan Lale , van den Bent Martin J. , Hoogstrate Youri , Naz-Khan Hina , Stubbs Andrew , van der Spek Peter , Böttcher René , Gao Ya , de Wit Maurice , Taal Walter , Oosterkamp Hendrika M. , Walenkamp Annemiek , Beerepoot Laurens V. , Hanse Monique C.J. , Buter Jan , Honkoop Aafke H. , van der Holt Bronno , Vernhout René M. , Smitt Peter A.E. Sillevis , Kros Johan M. , French Pim J.
Published: March 2023

Performance of DASL and RNA-seq on RNA isolated from FFPE tissues, technical replicates.
Supplementary Figure S2 from Exploring the Biomechanical Properties of Brain Malignancies and Their Pathologic Determinants In Vivo with Magnetic Resonance Elastography
Authors: Jamin Yann , Boult Jessica K.R. , Li Jin , Popov Sergey , Garteiser Philippe , Ulloa Jose L. , Cummings Craig , Box Gary , Eccles Suzanne A. , Jones Chris , Waterton John C. , Bamber Jeffrey C. , Sinkus Ralph , Robinson Simon P.
Published: March 2023

Supplementary Figure S2. Radiological presentation of intracranial U-87 MG, RG2 and MDA-MB-231 tumors.
Supplementary Figure S3 from Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin–GUCY2C Paracrine Signaling Axis
Authors: Lin Jieru E. , Colon-Gonzalez Francheska , Blomain Erik , Kim Gilbert W. , Aing Amanda , Stoecker Brian , Rock Justin , Snook Adam E. , Zhan Tingting , Hyslop Terry M. , Tomczak Michal , Blumberg Richard S. , Waldman Scott A.
Published: March 2023

Daily calorie intake and body weights in mice on lean, high carbohydrate (HC), or high fat (HF) diets.
Supplementary Figure S3 from Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity
Authors: Zhao Weina , Prijic Sara , Urban Bettina C. , Tisza Michael J. , Zuo Yan , Li Lin , Tan Zhi , Chen Xiaoling , Mani Sendurai A. , Chang Jeffrey T.
Published: March 2023

Drugs alter plasma membrane fluidity across cell lines and growth conditions, associated with changes in metastatic phenotypes.
Supplementary Figure S1 from Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity
Authors: Zhao Weina , Prijic Sara , Urban Bettina C. , Tisza Michael J. , Zuo Yan , Li Lin , Tan Zhi , Chen Xiaoling , Mani Sendurai A. , Chang Jeffrey T.
Published: March 2023

Embryonic EMT signature.
Supplementary Figures S1-S6 from Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
Authors: Picon-Ruiz Manuel , Pan Chendong , Drews-Elger Katherine , Jang Kibeom , Besser Alexandra H. , Zhao Dekuang , Morata-Tarifa Cynthia , Kim Minsoon , Ince Tan A. , Azzam Diana J. , Wander Seth A. , Wang Bin , Ergonul Burcu , Datar Ram H. , Cote Richard J. , Howard Guy A. , El-Ashry Dorraya , Torné-Poyatos Pablo , Marchal Juan A. , Slingerland Joyce M.
Published: March 2023

hASC characterization (S1); Co-culture of immature adipocytes with mammary epithelial cells increases pro-inflammatory cytokine expression (S2); Immature adipocyte or cytokine exposure increases abundance of sphere and colony forming cells without changing global cell proliferation (S3); Immature adipocyte or cytokine exposure increases matrigel invasion in vitro and tumor formation, vasculogenesis and metastasis in vivo (S4); Src mediates cytokine effects via ES-TF upregulation affecting soft agar colony growth but not cell cycle progression (S5); Cytokine-mediated increase in sphere formation is Sox2-dependent and miR302b upregulation drives further c-MYC and SOX2 gene expression (S6).
Supplementary Figures 1-4 from Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer
Authors: Espelin Christopher W. , Leonard Shannon C. , Geretti Elena , Wickham Thomas J. , Hendriks Bart S.
Published: March 2023

Supp. Figure 1 MM-302 and trastuzumab co-localize in BT474-M3 xenograft tumors. Supp. Figure 2 In vivo deposition of MM-302 is specifically increased by trastuzumab or T-DM1. Supp. Figure 3 Pharmacokinetics (PK) of MM-302 remains the same with or without co-administration of trastuzumab. Supp. Figure 4 Combination of MM-302 and trastuzumab demonstrates synergistic anti-tumor activity in models of HER2-positive breast and gastric cancer.
Supplementary Figure Legends 1-4 from Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer
Authors: Espelin Christopher W. , Leonard Shannon C. , Geretti Elena , Wickham Thomas J. , Hendriks Bart S.
Published: March 2023

Supp. Figure 1 MM-302 and trastuzumab co-localize in BT474-M3 xenograft tumors. Supp. Figure 2 In vivo deposition of MM-302 is specifically increased by trastuzumab or T-DM1. Supp. Figure 3 Pharmacokinetics (PK) of MM-302 remains the same with or without co-administration of trastuzumab. Supp. Figure 4 Combination of MM-302 and trastuzumab demonstrates synergistic anti-tumor activity in models of HER2-positive breast and gastric cancer.
Supplementary Figure S1 from ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis
Authors: Rodriguez Calleja Lidia , Jacques Camille , Lamoureux François , Baud'huin Marc , Tellez Gabriel Marta , Quillard Thibaut , Sahay Debashish , Perrot Pierre , Amiaud Jerome , Charrier Celine , Brion Regis , Lecanda Fernando , Verrecchia Franck , Heymann Dominique , Ellisen Leif W. , Ory Benjamin
Published: March 2023

p63-regulated microRNAs target the TGFÎ² pathway.
Supplementary Figure Legends from ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis
Authors: Rodriguez Calleja Lidia , Jacques Camille , Lamoureux François , Baud'huin Marc , Tellez Gabriel Marta , Quillard Thibaut , Sahay Debashish , Perrot Pierre , Amiaud Jerome , Charrier Celine , Brion Regis , Lecanda Fernando , Verrecchia Franck , Heymann Dominique , Ellisen Leif W. , Ory Benjamin
Published: March 2023

Legend for Supplementary Figures S1-S6
Table S4 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: March 2023

Gene Ontology (GO) terms significantly enriched among genes whose hypermethylation and downregulation are associated with high-risk disease (HyperDownHR).
Supplementary Table S3 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: March 2023

22 transcription factors (related to cancer pathway) potentially binding to MALAT1 promoter.
Supplementary Figures S1-S17 from An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer
Authors: Olow Aleksandra , Chen Zhongzhong , Niedner R. Hannes , Wolf Denise M. , Yau Christina , Pankov Aleksandr , Lee Evelyn Pei Rong , Brown-Swigart Lamorna , van ‘t Veer Laura J. , Coppé Jean-Philippe
Published: March 2023

Phospho-reactome curation workflow (S1); Proteins catalogued in PhosphoAtlas correspond to a unique subset of Protein-Protein Interactions, defined by their active, proven function in phospho-catalytic events (S2); Comparative connectivity between kinases, substrates and HPS's (S3); Most highly connected kinases and substrates (S4); Comparison between the number of enzyme - substrate pairs and the number of kinase - HPS - substrate connections across kinase subfamilies (S5); Disease ontology profile of AKT phospho-circuits (S6); Connectivity of AKT proteins to their upstream and downstream phospho-protein circuits (S7); Catalytic circuitry of AKT1 kinase: an expandable network of enzymatic interaction derived from mutation-prone phospho-target sites (S8); Identification of substrate proteins that are most affected by cancer-mutated peptides, and substrates that are not subject to alterations of their phospho-target sites (S9); Distribution and classification of SNP-altering target sites (S10); Heptameric target variants affecting phosphorylation sites mapped to COSMIC-curated tissue pathologies (S11); Identification of kinases impacted by cancer-mutations that alter their phosphorylatable target sites (S12); Map of the tumor kinome (S13, S14); Examples of kinase and substrate sub-networks, and the differential impact of tumor mutations on their phospho-signaling circuits (S15, S16, S17).
Supplemental Legends from Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model
Authors: Sacco Antonio , Roccaro Aldo M. , Ma Dongdong , Shi Jiantao , Mishima Yuji , Moschetta Michele , Chiarini Marco , Munshi Nikhil , Handin Robert I. , Ghobrial Irene M.
Published: March 2023

Legends for Supplemental Table S1 and Supplemental Figures S1-S3.
Supplemental Figure S2 from Cancer Cell Dissemination and Homing to the Bone Marrow in a Zebrafish Model
Authors: Sacco Antonio , Roccaro Aldo M. , Ma Dongdong , Shi Jiantao , Mishima Yuji , Moschetta Michele , Chiarini Marco , Munshi Nikhil , Handin Robert I. , Ghobrial Irene M.
Published: March 2023

Breast cancer cells colonize the CHT niches.
Supplementary Methods from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: March 2023

Supplemental materials and methods
Supplemental Figure 4 from Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis
Authors: Quick Laura , Young Robert , Henrich Ian C. , Wang Xiaoke , Asmann Yan W. , Oliveira Andre M. , Chou Margaret M.
Published: March 2023

CRISPR cell lines
Supplementary Table 4 from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: March 2023

Supplementary Table S4. Histology scores for CD4Stat3-/- and WT (CD4Stat3+/+) C57BL/6 mice colonized 7 days with ETBF.
Figure S9 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: March 2023

Effect of valproic (VA, 100 mg/kg, injection every second day for three weeks) on tumors formed by CW9019-Luc aRMS cells transplanted subcutaneously to athymic nude mice.
Cell line information from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: March 2023

This file contains the source of all cell lines used for the work described in the manuscript as well as the methods by which cell lines are authenticated at the repositories.
Figure S4 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: March 2023

Expression of genes influencing the myoD activity in SMS-CTR eRMS (SMS) and CW9019 aRMS (CW) cell lines cultured in growth medium (GM).
Supplementary Figure 2 from Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer
Authors: Regan Anderson Tarah M. , Ma Shi Hong , Raj Ganesh V. , Cidlowski John A. , Helle Taylor M. , Knutson Todd P. , Krutilina Raisa I. , Seagroves Tiffany N. , Lange Carol A.
Published: March 2023

DUSP1 and GILZ regulation and GR recruitment in MDA-MB-231 shControl and HIF1/2-shRNA cells.
Figure S8 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: March 2023

miR-214 and miR-148b do not significantly affect proliferation
Figure S4 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: March 2023

miR-148b expression modulations in melanoma cells