bluuebunny/crossref_metadata_2025 huggingface dataset:
Cinema education method, is it work for group guidance and counseling?
Authors: Mamahit Henny Christine
Published: November 2020

Group guidance and counseling services are services provided to students to develop life skills both academically and non-academically. Group guidance and counseling services are intended to develop attitudes and behaviors that bring goodness to students. The cinema education method is a method that uses film media to provide group guidance and counseling services. The cinema education method can be a means to help students understand their living conditions, the needs they want to fulfill, and can provide a perception that sees that everything or problems has a way out. Learning experiences obtained from films can help students develop ideas or solutions to help themselves.
The End of the West as We Know It: Must World Civilization Be Redefined?
Authors: Ritz Hauke
Published: November 2020

Our present world is quickly transformed by the combined forces of particular megatrends. Especially if we connect two of them, namely the technological trend, which enables for the first time in history a surveillance state, and the trend towards a rising concentration of wealth; then it becomes clear that those two developments tend to strengthen each other. With the same necessity, with which the Republican Age was heralded through the rise of the bourgeoisie, with the same inevitability it will vanish, once the wealth distribution has reached a critical point. It seems humankind is indeed heading towards a kind of dystopian future similar to those described in many science fiction novels, where a feudal class society is usually combined with a high technology surveillance grid. This begs the question as to whether or not we can correct the current developmental trajectory of history. Are there counterforces which could help us to guide history in the right direction?
Traditional Healthcare and Patient Response Services in Karo Regency
Authors: Sembiring Sri Agustina , Harahap R Hamdani , Amir Amri
Published: November 2020

Local knowledge developed based on experience has been tested for use for centuries and adapted to local culture and environment as well as in Karo Regency. Karo people have long known traditional medicines are diverse, know several types of diseases as well as how to treat them. This knowledge is one of the local wisdom that persists today. This research is qualitative, the determination of informants using  Snowball Sampling techniques, data collected through in-depth interviews and observations. Key Informant as many as 17 people from 7 sub-districts. The traditional form of health care in Karo regency is 67% skill, herb 27%, and combination (skill and herb) 6%. Moreover, the age which has a small percentage (20-30 years) of 5.58%, the most significant 51 years and above with a percentage of 70%, how to acquire the most skills is hereditary (empirical) as much as 71%, the most jobs besides Hattra are farmers (59%) and does not have a permit /STPT of 82%. Of the 40 respondents, 80% expressed dissatisfaction and 20% expressed dissatisfaction with hattra's service. The traditional herb by ethnic Karo is known as the "Karo remedy".. Tanaman drugs are often used gagatan harimo, lempuyang, pepper, garlic, shallots, bahing, tinggeren dredge flowers, and small oranges. Karo uses this plant as a raw material for the manufacture of karo oil, param and tawar
Маневрений підхід – концепція асиметричних сухопутних операцій НАТО
Authors: Ролін І. Ф. , Семон Б. Й. , Марущенко В. В. , Чернявський І. Ю.
Published: November 2020

Стаття є логічним продовженням і доповненням розв'язання проблеми, яка була висвітлена в першому номері журналу "Наука і оборона" за 2019 рік. Суть проблеми полягає в наявності розбіжностей у розумінні українськими фахівцями принципів і військової термінології країн – членів НАТО, особливо у випадках, коли концептуально важливі терміни не мають прямого еквівалентного перекладу. Дана проблема може бути суттєвою перешкодою в процесі досягнення сумісності сил оборони України з силами НАТО.На підставі аналізу сучасної доктрини НАТО щодо сухопутних операцій, змісту базових понять, які застосовуються в державах Північноатлантичного альянсу, висвітлено концептуальні розбіжності в підходах до управління військовою операцією порівняно з існуючими в силах оборони України. Розкрито ключові принципи маневреного підходу (manoeuvrist approach) до ведення сухопутних операцій, а також ідеї та принципи децентралізованого управління (mission command) та умови щодо його впровадження.Показано, що маневрений підхід є ключовою концепцією сучасної західної доктрини сухопутних операцій, який ставить на перший план розуміння ситуації і маніпулювання людською природою, використання вразливих сторін противника, застосування непрямих і оригінальних способів дій та мінімізацію втрат. Цей підхід пропонує швидкі результати або результати значно більші, ніж застосовані ресурси, тому він є привабливим для слабшої сторони в числовому відношенні або сторони, яка хоче звести до мінімуму обсяг задіяних ресурсів.Зроблено висновок про необхідність в процесі створення системи управління силами оборони за євроатлантичними стандартами змінювати не тільки структури і оснащеність органів управління, але й термінологію та процедури у сфері управління військами (силами), а в більш широкому сенсі – також і психологію військових керівників (командирів), завдяки відмови від авторитарного стилю керівництва, підвищення ролі ініціативи та самостійності при виконанні оперативних (бойових) завдань.
New versions of classification databases: changes and peculiarities
Authors:   Russian National Public Library for Science and Technology, Zaytseva Ekaterina
Published: November 2020

The paper deals with the new electronic versions of classification systems developed by Association ELNIT and Russian NPLSaT. Changes that characterize new versions of BBK, UDC and GRNTI classification databases are described. Their characteristics, functional features and advantages in comparison with classification printed versions are defined.
Ethical Cyber Behaviour among Undergraduate Students in Selected African Universities. An Overview
Authors:   University of Zululand, Aderibigbe Nurudeen , Ocholla Dennis N ,   University of Zululand
Published: November 2020

This study examined the ethical behaviour of undergraduate students in relation to cyber technology at the University of Zululand (UNIZULU), South Africa, and the Federal University of Agriculture in Abeokuta (FUNAAB), Nigeria. We adopted the pragmatic research paradigm that combines both quantitative and qualitative research methods through the survey method. The sample for the study was drawn from undergraduate students in two purposively selected universities in South Africa and Nigeria. Overall, 450 undergraduate students were invited to participate in the survey; 380 respondents completed and returned the questionnaire, resulting in a response rate of 84.4%. 14 of the expected 16 members of staff of both Information & Communication Technology Resource Centre ICTREC and Information Technology Section ITS were interviewed, resulting in a response rate of 88%. A combination of quantitative and qualitative approaches was used for data analysis. Most of the respondents from the sampled universities reported that they were aware of what constitutes unethical cyber behaviour. Further, the participants (98; 52.1%) revealed that they had never received ethical orientation/training in the university on cyber behaviour, cyber space, or cyber technology. Challenges facing the students is reported. The study recommends that universities should sustain orientation/training programmes on cyber ethics and cyber security awareness at the start of each academic year, especially for newly enrolled students so that they can act responsibly when using the university’s cyberspace. The results of this study may spark further discussions and research on cyber technology access and use in contemporary society.
Prototyping program platform to generate modern library services
Authors:   Institute of Computational Technologies of the Siberian Branch of the Russian Academy of Sciences, Kolobov Oleg , Knyazeva Anna ,   Institute of Computational Technologies of the Siberian Branch of the Russian Academy of Sciences, Turchanovsky Igor ,   Institute of Computational Technologies of the Siberian Branch of the Russian Academy of Sciences
Published: November 2020

A prototype for program platform for library services is examined. It is based on the microservice architecture and can be used as an individual service for various programs and apps, based on open protocol. The platform prototype is characterized in brief, along with different strategies for generating modern library services, i. e. OPAC, Distributed E-catalog, Awareness System and SEO. Platform prototype implementation does not depend on proprietary software.
«The 69 parallel north: Place of registration». Rare books in the collection of the Murmansk State Regional Universal Scientific Library: Studies, conservation, and digitization
Authors:   Murmansk State Regional Universal Scientific Library, Kuznetsova Elena
Published: November 2020

The author describes the collection of rare books of Murmansk State Regional Universal Scientific Library in the context of the history of Murmansk city and the Kola Peninsula. The oldest and the most unique editions in the collection are described, among them the old-print and local history books, rarities of the House of Romanov. The experience of managing the rare books collection is discussed: studies, popularization, preservation through conservation methods, development of subject collections and the corresponding The Kola North E-library section.
Modern trends in typhlobibliography in the Republic of Sakha (Yakutia)
Authors:   Republicn Library for the Blind, Nikitina Aytalina
Published: November 2020

New vectors in typhlobibliographical activities of Republican Library for the Blind are examined: the Typhlopole full-text database and the retrospective national bibliography «Publications for the blind and visually impaired in the Republic of Sakha (Yakutia) in 1971–2021».
Widening the horizons: Information space of the library for the blind as the resource to improve quality of life of visually impaired people
Authors:   Regional Special Library for the Blind, Novikova Olga
Published: November 2020

The special library acts as the cultural and educational center for visually impaired people, and as the center for continuing education. The multifunctional performance of the library is substantiated. The joint projects accomplished in cooperation with theatres and museums and aimed at integrating the visually impaired people into the society are described. Advanced training projects for the library professionals accomplished in 2018 are discussed.
Checking library collection enables to analyze its composition as exemplified by the Pushkin State Museum of Fine Arts Research Library
Authors:   The Pushkin State Museum of Fine Arts, Parkhomenko Olga
Published: November 2020

The Library of the Pushkin State Museum of Fine Arts is rich in rare and unique publications, and those of memorial value. The collection checking envisages visual revision and analysis of every book, and during this process the specialists revealed a number of valuable publications for further research. Also all registered publication went through the stage of initial collection specification (e.g., Rumyantsev museum collection, collection of the New Western Arts Museum, memorial libraries, etc). Currently, this information has been being entered into the e-catalog. This will enable to verify special arrays within the Research Library’s collection and simplify investigations into historical and memorial book collections and individual valuable publications.
Scientific and information work at Samara University Library: Technological solutions on the 1C: Enterprise platform
Authors:   Samara University, Petrova Olga , Bulycheva Olga ,   1C Company
Published: November 2020

The tasks of integrated information support and university library management computerization are examined as related to the federal state standards. Current trends in e-libraries’ development and new elements of the national information infrastructure are considered. Goals, accomplishments and prospects for Samara University Library are analyzed. The issues of building an integrated digital information and education environment of the university based on the 1C: Enterprise platform are discussed.
A promising model for academic libraries to interact in building and using full-text resources
Authors:   State Public Scientific and Technical Library of the Russian Academy of Sciences Siberian Branch, Bazhenov Sergey , Stukalova Anna ,   State Public Scientific and Technical Library of the Russian Academy of Sciences Siberian Branch
Published: November 2020

Approaches towards digitizing and preserving the core collection of the academic library network and solutions with IRBIS64+ e-library are examined.
Developing solution for implementing IRBIS LAS on the PHP platform
Authors:   Elnit Association, Batrak Ivan
Published: November 2020

Designing a cross-platform software for implementing IRBIS LAS on the PHP platform is discussed. The new print format language interpreter for IRBIS LAS based on J-ISIS and CISIS formatting language features and capabilities, is also developed.
The right to reading: The principles of the Marrakesh Treaty in Russia
Authors:   St. Petersburg State Library for the Blind and Visually Impaired, Battalova Sania
Published: November 2020

The Marrakesh Treaty on facilitating access for blind and visually impaired people and people with print disabilities to published works is one of the first international treaties in copyright aimed at widening the access to printed works under the copyright for up to 300 million people with print disabilities. The member states are to amend their national laws correspondingly. Russia ratified the Treaty in November, 2017 2 [4] and on May 8, 2018, the Treaty will come into effect in this country. By doing this, Russia accepts responsibility to eliminate legislative barriers preventing inequality of blind, visually impaired people and persons with print disabilities in the access to books and other materials and widening this access. The key Treaty provisions are analyzed; amendments to and provisions of the RF copyright law are discussed as they are to enable the libraries and other organizations to provide the rights to equal access to the information and knowledge for the target groups of population.
The current state and current issues of phase conservation of document collections of the RF libraries, museums and archives
Authors:   Art Technics Company, Galkina Lyudmila
Published: November 2020

The current state of phase conservation of document collections of the RF heritage institutions is analyzed. The achievements, difficulties and drawbacks in this area are discussed, in particular, lacking the comprehensive standards and technical regulations. Tasks to be accomplished to solve these problems are formulated; measures to develop standards and regulations are substantiated; expected information technological and economic efficiency of these measures is evaluated.
«Ecology, Books and Us». The program of ecological education in Library of Family Reading of Lomonosov town
Authors:   Centralized Library System of St. Petersburg Petrodvorets District, Gloza Natalya
Published: November 2020

The program Family Reading Library in the town of Lomonosov: «Ecology, Books and Us» is discussed. The program is targeted at building ecological literacy and culture in the children, from preschoolers to senior schoolchildren of St. Petersburg Petrodvorets District.
Trends in the information and library technologies computerization and their practical implantation as exemplified by MegaPro Automated Integrated Library System
Authors:   Data Express Company, Gribov Vladimir , Efremov Sergey ,   Data Express Company, Levova Lyudmila ,   Data Express Company
Published: November 2020

The main vectors of step changes of ALIS/AILS are discussed to meet new challenges modern libraries are facing. Implementation options for these trends are examined by the example of the MegaPro Automated Integrated Library System.
PENAMBAHAN NEUROMUSCULAR TRAINING PROGRAM DALAM MENINGKATKAN PERFORMA FUNGSIONAL ANKLE ATLET SEPAK BOLA LAKI-LAKI DENGAN RIWAYAT ANKLE SPRAIN
Authors: Pramono Dominggus Ruku Yudit , Tinduh Damayanti , Harlina Harlina
Published: November 2020

When there is an ankle sprain injury the athlete has decreased functional ability and decreased instability of the ankle joint. One of the actions used to reduce the risk of injury and increase the performance of athletes is by providing a Neuromuscular Training Program (NMT). This study to prove the effect of the provision of the Neuromuscular Training Program on the functional performance. This study used a Randomized Pre Test and Post Test Group Design study design. Respondents of this study were male soccer athletes, amounting to 18 athletes who met the inclusion criteria, then divided into 2 groups randomly, each group consisted of 9 respondents. The study showed that there were differences in improvement in functional performance after the administration of the Neuromuscular Training Program in male soccer athletes with a history of ankle sprain. In the treatment group shows the results of functional performance (SLHT) with a value of p = 0,000 indicates a significant effect. Then the results of subjective functional performance measurements using Cumberland Ankle and Instability Tools (CAIT) in the treatment group showed the results of functional performance (CAIT) with a value of p = 0.005. From the results of the study that there were differences and improves in functional performance after the administration of the Neuromuscular Training Program in male soccer athletes with a history of ankle sprain.
Sivil Toplum Kuruluşlarına Göre İmam-Hatip Okulları: Kurumsal Varlık ve Meslek Lisesi Statüsü
Authors: ARICAN Sümeyra
Published: November 2020

Sivil toplum kuruluşlarının gerek dünya çapında gerekse Türkiye özelinde etkinliğinin gittikçe arttığı gözlemlenmektedir. Politik baskı unsuru konumlanan bu kuruluşlar hükümet politikalarını etkileyebilmektedirler. Artan bu etkinliklerinin mesleki din eğitimine yansımalarının ele alınmadığı fark edilmiştir. Bu çalışmada Cumhuriyet dönemi boyunca pek çok tartışmanın odağında yer alan ve tarihi sürecinde sürekli değişen uygulamalarla gündemden düşmeyen bir eğitim kurumu olan imam hatip liselerine sivil toplum kuruluşları cephesinden bakılmaktadır. Sivil toplum kuruluşlarının imam hatip liselerinin kurumsal varlığı ve meslek lisesi statüsüne yaklaşımları ile bu yaklaşımlarının benzerlik ve farklılıklarının kendi araştırmalarından hareketle ortaya konulması amaçlanmaktadır. Nitel çoklu durum çalışması olan bu araştırmada, maksimum çeşitlilik örneklemesi ile seçilen sivil toplum kuruluşlarının araştırma raporlarından edinilen veriler doğrultusunda örgün, mesleki din eğitimine yaklaşımları iki ana tema halinde ele alınmıştır. Bu temalar; “laik bir ülkede var olmak” ve “meslek lisesi statüsünü yeniden düşünmek” olarak isimlendirilmiştir. Araştırma sonucunda sivil toplum kuruluşlarının araştırma raporlarındaki tartışmalarda çoğunlukla bu eğitim kurumunun varlığının laiklik ilkesiyle ilişkisine odaklanıldığı, meslek lisesi olarak statüsünün tartışmaya açıldığı, mezunlarının yüksek din öğretimine yönelmedikleri yönünde vurgular tespit edilmiştir. Tevhidi Tedrisat Kanunu ve laiklik ilkesi imam hatip liselerinin varlığına dair sorgulama ve savunma söylemlerinde önemli bir dayanak noktası olarak konumlanmaktadır.
PENERAPAN MODEL PEMBELAJARAN KOOPERATIF BERBANTUAN MEDIA GAMBAR DI KOTA MALANG
Authors: Husniyah Fitri Alfi
Published: November 2020

This study aims to determine the efforts of teachers in improving class V Arabic writing skills at MI Hidayatul Mubtadi'in Tasikmadu Malang City. The problem faced is that there are still many students who lack Arabic writing skills because some students do not understand and have not read fluently the letters in Arabic Mufrodat, thus impacting students' writing skills that are not in accordance with the completeness of skills write Arabic. Sources of data were obtained from Arabic class V teacher and class V students totaling 28 children, this study used a qualitative approach with the type of research used was classroom action research, where data obtained based on the results of interviews, observations, and documentation analyzed with data reduction, data presentation and verification or conclusions.The results of this study indicate that teachers use several efforts that have been designed and applied in learning so that efforts can be made to improve students' Arabic writing skills.
DEVELOPMENT OF A TEACHING BOOK BASED ON LOCAL WISDOM OF JEPARA DISTRICT FOR CLASS V ELEMENTARY SCHOOL STUDENTSDEVELOPMENT OF A TEACHING BOOK BASED ON LOCAL WISDOM OF JEPARA DISTRICT FOR CLASS V ELEMENTARY SCHOOL STUDENTS
Authors: Arifin Zaenal
Published: November 2020

This study aims to: (1) develop thematic textbooks based on local wisdom of our best friend's environmental theme material for grade V elementary school students, (2) Know the validity, practicality and effectiveness of thematic textbooks based on local wisdom of our best friend's environmental theme material for grade students V elementary school. The development of thematic textbook learning media based on local wisdom uses the Research and Development (R & D) method. The development stages include: (1) Potentials and problems, (2) Data collection, (3) Product design, (4) Design validation, (5) Design revision, (6) Product testing, (7) Product revision (Sugiyono, 2016). The research was conducted with 33 students from class V SDN 2 Sendang Jepara Regency. Initial product development is a process of making media based on needs analysis. Expert testing or validation was carried out by 2 experts, namely media experts and material experts. The data collection method in this research is observation, interview, and questionnaire. The data analysis technique used descriptive analysis and comparison test of two independent groups, namely using the independent t-test. Based on the results of the trial, this thematic teaching material is very valid, very interesting, effective and can be applied in learning. This can be seen from the results of the validation test from three experts which show that the product is good. The results of the effectiveness test showed that the experimental class students had better learning outcomes than the control class. This means that textbooks based on local wisdom of Jepara Regency are developed effectively
Le champ opératoire de l'activisme judiciaire supranational en Afrique. Une tentative de systématisation
Authors: Zouapet Apollin Koagne
Published: November 2020

Zone géographique où le « buissonnement juridictionnel  » des relations internationales a connu son expression la plus vivace, l'Afrique est également le continent où la vulnérabilité des cours et tribunaux internationaux a sans doute également le plus mis en exergue. Prenant un angle d'analyse différent, la présente réflexion examine les stratégies et moyens déployés par le juge international africain pour exercer sa mission, à la fois de façon efficace et prudente. L'article essaie ainsi de mettre en exergue les ressorts d'une politique jurisprudentielle des juridictions africaines, en en soulignant les forces et les inévitables faiblesses.
Metabolic syndrome: regulation of metabolism in men (literature review)
Authors: Drygina L. B.
Published: November 2020

The review of modern literature on pathogenetic ways of formation of metabolic syndrome in men of different age groups, athletes, University students, as well as persons related to dangerous professions (military personnel, rescuers, liquidators of the consequences of the Chernobyl accident) is presented. The role of insulin resistance, leptin resistance, chronic sluggish inflammation, desynchronosis, and obesity is discussed. Literature data on the relationship of the gut microbiota and vitamin D levels with obesity are presented. The analysis of patent research in the field of clinical and laboratory diagnostics of metabolic syndrome. The role of stress in the development of metabolic syndrome in dangerous professions is shown. Analysis of data published in the literature suggests that hyperleptinemia and low androgen levels can be considered as an additional laboratory marker of MS in liquidators of the Chernobyl accident.
Delivering a resilient, net zero economy: How do we transition infrastructure at pace in the race to zero?
Authors: (CLG) The Prince of Wales’s Corporate Leaders Group
Published: November 2020

This webinar is the first of the series: Delivering a resilient, net zero economy, providing a call to action and supporting enhanced collaboration between policymakers and business leaders that feeds into UK business climate leadership, policy, the green recovery and the Government’s COP26 campaign. The webinar’s aim is to examine the challenges of how we transition national infrastructure towards a resilient net zero vision. It will take a place-based approach to look at the role of business in accelerating the transition, opportunities for innovation, where new approaches may be required and the policy levers required to release private investment.
Membrane Dynamics and Organization of the Phagocyte NADPH Oxidase in PLB-985 Cells
Authors: Joly Jérémy , Hudik Elodie , Lecart Sandrine , Roos Dirk , Verkuijlen Paul , Wrona Dominik , Siler Ulrich , Reichenbach Janine , Nüsse Oliver , Dupré-Crochet Sophie
Published: November 2020

Neutrophils are the first cells recruited at the site of infections, where they phagocytose the pathogens. Inside the phagosome, pathogens are killed by proteolytic enzymes that are delivered to the phagosome following granule fusion, and by reactive oxygen species (ROS) produced by the NADPH oxidase. The NADPH oxidase complex comprises membrane proteins (NOX2 and p22phox), cytoplasmic subunits (p67phox, p47phox, and p40phox) and the small GTPase Rac. These subunits assemble at the phagosomal membrane upon phagocytosis. In resting neutrophils the catalytic subunit NOX2 is mainly present at the plasma membrane and in the specific granules. We show here that NOX2 is also present in early and recycling endosomes in human neutrophils and in the neutrophil-like cell line PLB-985 expressing GFP-NOX2. In the latter cells, an increase in NOX2 at the phagosomal membrane was detected by live-imaging after phagosome closure, probably due to fusion of endosomes with the phagosome. Using super-resolution microscopy in PLB-985 WT cells, we observed that NOX2 forms discrete clusters in the plasma membrane. The number of clusters increased during frustrated phagocytosis. In PLB-985NCF1ΔGT cells that lack p47phox and do not assemble a functional NADPH oxidase, the number of clusters remained stable during phagocytosis. Our data suggest a role for p47phox and possibly ROS production in NOX2 recruitment at the phagosome.
Predictive Factor for COVID-19 Worsening: Insights for High-Sensitivity Troponin and D-Dimer and Correlation With Right Ventricular Afterload
Authors: Goudot Guillaume , Chocron Richard , Augy Jean-Loup , Gendron Nicolas , Khider Lina , Debuc Benjamin , Aissaoui Nadia , Peron Nicolas , Hauw-Berlemont Caroline , Vedie Benoit , Cheng Charles , Mohamedi Nassim , Krzisch Daphné , Philippe Aurélien , Puscas Tania , Hermann Bertrand , Brichet Julie , Juvin Philippe , Planquette Benjamin , Messas Emmanuel , Pere Hélène , Veyer David , Gaussem Pascale , Sanchez Olivier , Diehl Jean-Luc , Mirault Tristan , Smadja David M.
Published: November 2020

Background: Coronavirus disease 2019 (COVID-19) has been associated with cardiovascular complications and coagulation disorders.

Objectives: To explore clinical and biological parameters of COVID-19 patients with hospitalization criteria that could predict referral to intensive care unit (ICU).

Methods: Analyzing the clinical and biological profiles of COVID-19 patients at admission.

Results: Among 99 consecutive patients that fulfilled criteria for hospitalization, 48 were hospitalized in the medicine department, 21 were first admitted to the medicine ward department and referred later to ICU, and 30 were directly admitted to ICU from the emergency department. At admission, patients requiring ICU were more likely to have lymphopenia, decreased SpO2, a D-dimer level above 1,000 ng/mL, and a higher high-sensitivity cardiac troponin (Hs-cTnI) level. A receiver operating characteristic curve analysis identified Hs-cTnI above 9.75 pg/mL as the best predictive criteria for ICU referral [area under the curve (AUC), 86.4; 95% CI, 76.6–96.2]. This cutoff for Hs-cTnI was confirmed in univariate [odds ratio (OR), 22.8; 95% CI, 6.0–116.2] and multivariate analysis after adjustment for D-dimer level (adjusted OR, 20.85; 95% CI, 4.76–128.4). Transthoracic echocardiography parameters subsequently measured in 72 patients showed an increased right ventricular (RV) afterload correlated with Hs-cTnI (r = 0.42, p = 0.010) and D-dimer (r = 0.18, p = 0.047).

Conclusion: Hs-cTnI appears to be the best relevant predictive factor for referring COVID-19 patients to ICU. This result associated with the correlation of D-dimer with RV dilatation probably reflects a myocardial injury due to an increased RV wall tension. This reinforces the hypothesis of a COVID-19-associated microvascular thrombosis inducing a higher RV afterload.
D-Amphetamine Accelerates Recovery of Consciousness and Respiratory Drive After High-Dose Fentanyl in Rats
Authors: Moody Olivia A. , Zhang Edlyn R. , Arora Vipin , Kato Risako , Cotten Joseph F. , Solt Ken
Published: November 2020

In the United States, fentanyl causes approximately 60,000 drug overdose deaths each year. Fentanyl is also frequently administered as an analgesic in the perioperative setting, where respiratory depression remains a common clinical problem. Naloxone is an efficacious opioid antagonist, but it possesses a short half-life and undesirable side effects. This study was conducted to test the hypothesis that d-amphetamine ameliorates respiratory depression and hastens the return of consciousness following high-dose fentanyl. Behavioral endpoints (first head movement, two paws down, and return of righting), arterial blood gas analysis and local field potential recordings from the prefrontal cortex were conducted in adult rats after intravenous administration of of fentanyl (55 µg/kg) at a dose sufficient to induce loss of righting and respiratory depression, followed by intravenous d-amphetamine (3 mg/kg) or saline (vehicle). D-amphetamine accelerated the time to return of righting by 36.6% compared to saline controls. D-amphetamine also hastened recovery of arterial pH, and the partial pressure of CO2, O2 and sO2 compared to controls, with statistically significant differences in pH after 5 min and 15 min. Local field potential recordings from the prefrontal cortex showed that within 5 min of d-amphetamine administration, the elevated broadband power <20 Hz produced by fentanyl had returned to awake baseline levels, consistent with the return of consciousness. Overall, d-amphetamine attenuated respiratory acidosis, increased arterial oxygenation, and accelerated the return of consciousness in the setting of fentanyl intoxication. This suggests that d-amphetamine may be a useful adjunct or alternative to opioid receptor antagonists such as naloxone.
Genome-Wide Association Studies Detect Multiple QTLs for Productivity in Mesoamerican Diversity Panel of Common Bean Under Drought Stress
Authors: Valdisser Paula Arielle Mendes Ribeiro , Müller Bárbara S. F. , de Almeida Filho Janeo Eustáquio , Morais Júnior Odilon Peixoto , Guimarães Cléber Morais , Borba Tereza C. O. , de Souza Isabela Pavanelli , Zucchi Maria Imaculada , Neves Leandro G. , Coelho Alexandre S. G. , Brondani Claudio , Vianello Rosana Pereira
Published: November 2020

Drought stress is an important abiotic factor limiting common bean yield, with great impact on the production worldwide. Understanding the genetic basis regulating beans’ yield and seed weight (SW) is a fundamental prerequisite for the development of superior cultivars. The main objectives of this work were to conduct genome-wide marker discovery by genotyping a Mesoamerican panel of common bean germplasm, containing cultivated and landrace accessions of broad origin, followed by the identification of genomic regions associated with productivity under two water regimes using different genome-wide association study (GWAS) approaches. A total of 11,870 markers were genotyped for the 339 genotypes, of which 3,213 were SilicoDArT and 8,657 SNPs derived from DArT and CaptureSeq. The estimated linkage disequilibrium extension, corrected for structure and relatedness (r2sv), was 98.63 and 124.18 kb for landraces and breeding lines, respectively. Germplasm was structured into landraces and lines/cultivars. We carried out GWASs for 100-SW and yield in field environments with and without water stress for 3 consecutive years, using single-, segment-, and gene-based models. Higher number of associations at high stringency was identified for the SW trait under irrigation, totaling ∼185 QTLs for both single- and segment-based, whereas gene-based GWASs showed ∼220 genomic regions containing ∼650 genes. For SW under drought, 18 QTLs were identified for single- and segment-based and 35 genes by gene-based GWASs. For yield, under irrigation, 25 associations were identified, whereas under drought the total was 10 using both approaches. In addition to the consistent associations detected across experiments, these GWAS approaches provided important complementary QTL information (∼221 QTLs; 650 genes;r2from 0.01% to 32%). Several QTLs were mined within or near candidate genes playing significant role in productivity, providing better understanding of the genetic mechanisms underlying these traits and making available molecular tools to be used in marker-assisted breeding. The findings also allowed the identification of genetic material (germplasm) with better yield performance under drought, promising to a common bean breeding program. Finally, the availability of this highly diverse Mesoamerican panel is of great scientific value for the analysis of any relevant traits in common bean.
Lumáwig: An Efficient Algorithm for Dimension Zero Bottleneck Distance Computation in Topological Data Analysis
Authors: Ignacio Paul Samuel , Bulauan Jay-Anne , Uminsky David
Published: November 2020

Stability of persistence diagrams under slight perturbations is a key characteristic behind the validity and growing popularity of topological data analysis in exploring real-world data. Central to this stability is the use of Bottleneck distance which entails matching points between diagrams. Instances of use of this metric in practical studies have, however, been few and sparingly far between because of the computational obstruction, especially in dimension zero where the computational cost explodes with the growth of data size. We present a novel efficient algorithm to compute dimension zero bottleneck distance between two persistent diagrams of a specific kind which runs significantly faster and provides significantly sharper approximates with respect to the output of the original algorithm than any other available algorithm. We bypass the overwhelming matching problem in previous implementations of the bottleneck distance, and prove that the zero dimensional bottleneck distance can be recovered from a very small number of matching cases. Partly in keeping with nomenclature traditions in this area of TDA, we name this algorithm Lumáwig as a nod to a deity in the northern Philippines, where the algorithm was developed. We show that Lumáwig generally enjoys linear complexity as shown by empirical tests. We also present an application that leverages dimension zero persistence diagrams and the bottleneck distance to produce features for classification tasks.
The Coexistence of Local and Global Food Supply Chains: The Lombardy Region Case Study
Authors: Mazzocchi Chiara , Corsi Stefano , Ruggeri Giordano
Published: November 2020

Over the last years, the trust of consumers in the quality and sustainability of the food system has weakened due to the disconnection between producers and consumers. Alternative Food Networks (AFNs) and Short Food Supply Chains (SFSCs), born out of the perceived loss of trust in the globalized food system, are trying to shorten the gap between farmers and consumers. Nowadays, many scholars agree that local and global food systems coexist, and consumers usually buy both in local and in global food chains. Our study aims to understand the factors that affect the development of AFNs with a specific focus on the interactions with small- and large-scale food retailing in the Lombardy region in the north of Italy. We employ an Ordinary Least Square (OLS) model, on a municipal scale, in which the dependent variable measures the number of participatory activities carried out by farmers and consumers in AFNs. The main results highlight that conventional large retailers and alternative food networks are linked, and that the coexistence of the two market channels may lead to the development for both of them. Contrarily, where small stores exist, they may compete with an alternative food channel, as they offer similar products and services.
Grazing Intensity Impacts on Herbage Mass, Sward Structure, Greenhouse Gas Emissions, and Animal Performance: Analysis of Brachiaria Pastureland
Authors: Ruggieri Ana Cláudia , Cardoso Abmael da Silva , Ongaratto Fernando , Casagrande Daniel Rume , Barbero Rondineli Pavezzi , Brito Liziane de Figueiredo , Azenha Mariane Vieira , Oliveira André Alves , Koscheck Jefferson Fabiano Werner , Reis Ricardo Andrade
Published: November 2020

A 7 year experiment (2008–2014) evaluated cattle grazing intensity (sward height) effects on herbage mass, forage quality, and greenhouse gas emissions in continuously stocked pastures containing the tropical ‘Marandu’ palisade grass (Brachiaria brizantha (Hochst. ex A. Rich) Stapf cv. Marandu). The experiment consisted of three sward height treatments (15, 25, and 35 cm) and six replicates. There were four periods each year during the rearing phase. Significant effects were found for herbage mass, proportions of leaf and stem, crude protein, neutral detergent fiber, acid detergent fiber, lignin, animal performance, enteric methane (CH4), and greenhouse gas (GHG) emissions from soils. When the canopy height increased from 15 to 35 cm, the herbage mass rose from 5.23 to 9.86 kg t ha−1, leaf percentage decreased, and stem percentage increased. Crude protein content averaged 14.2%, and neutral detergent fiber averaged 58%. Average daily gain averaged 0.67, 0.81, and 0.90 kg −1 head−1, while live weight gain ha–1 was 649, 530, and 439 kg for the 15, 25, and 35 cm treatments, respectively. The weather variables explained the GHG emissions, interannual herbage mass, and structure variations.
Overexpression of BvHb2, a Class 2 Non-Symbiotic Hemoglobin from Sugar Beet, Confers Drought-Induced Withering Resistance and Alters Iron Content in Tomato
Authors: Gisbert Carmina , Timoneda Alfonso , Porcel Rosa , Ros Roc , Mulet José M.
Published: November 2020

Drought stress is one of the major threats to agriculture and concomitantly to food production. Tomato is one of the most important industrial crops, but its tolerance to water scarcity is very low. Traditional plant breeding has a limited margin to minimize this water requirement. In order to design novel biotechnological approaches to cope with this problem, we have screened a plant cDNA library from the halotolerant crop sugar beet (Beta vulgaris L.) for genes able to confer drought/osmotic stress tolerance to the yeast model system upon overexpression. We have identified the gene that encodes BvHb2, a class 2 non-symbiotic hemoglobin, which is present as a single copy in the sugar beet genome, expressed mainly in leaves and regulated by light and abiotic stress. We have evaluated its biotechnological potential in the model plant Arabidopsis thaliana and found that BvHb2 is able to confer drought and osmotic stress tolerance. We also generated transgenic lines of tomato (Solanum lycopersicum) overexpressing BvHb2 and found that the resulting plants are more resistant to drought-induce withering. In addition, transgenic lines overexpressing BvHb2 exhibit increased levels of iron content in leaves. Here, we show that class 2 non-symbiotic plant hemoglobins are targets to generate novel biotechnological crops tolerant to abiotic stress. The fact that these proteins are conserved in plants opens the possibility for using Non-GMO approaches, such as classical breeding, molecular breeding, or novel breeding techniques to increase drought tolerance using this protein as a target.
Side Effects of Pesticides on the Olive Fruit Fly Parasitoid Psyttalia concolor (Szépligeti): A Review
Authors: Pinheiro Lara A. , Dáder Beatriz , Wanumen Andrea C. , Pereira José Alberto , Santos Sónia A. P. , Medina Pilar
Published: November 2020

Pesticide applications in olive orchards could alter the biological control of parasitoid Psyttalia concolor Szépligeti (Hymenoptera: Braconidae) on the key pest Bactrocera oleae Rossi (Diptera: Tephritidae). Psyttalia concolor adults can be contaminated by exposure to spray droplets, contact with treated surfaces or oral uptake from contaminated food sources. Pesticides impact both pest and parasitoid populations when they coexist in time and space, as they reduce pest numbers available for parasitoids and might cause toxic effects to parasitoids from which they need to recover. Therefore, the appropriate timing and application of selective chemical treatments provides the opportunity to incorporate this parasitoid in the IPM of B. oleae. This manuscript reviews the current literature on lethal and sublethal effects of insecticides, fungicides, herbicides, and biopesticides on P. concolor. Insecticides were generally more toxic, particularly organophosphates and pyrethroids, while herbicides and biopesticides had less effects on mortality and reproductive parameters. Some fungicides were quite harmful. Most of the studies were conducted in laboratory conditions, focused on reproduction as the only sublethal effect, exclusively considered the effect of a single pesticide and persistence was hardly explored. Field studies, currently quite scarce, are absolutely needed to satisfactorily assess the impact of pesticides on P. concolor.
Modeling the Emergence of Echinochloa sp. in Flooded Rice Systems
Authors: Goulart Francisco A. P. , Zandoná Renan R. , Schmitz Maicon F. , Ulguim André R. , Andres André , Agostinetto Dirceu
Published: November 2020

Barnyard grass (Echinochloa sp.) is one of the main rice weeds. Knowledge of its emergence can support management measures. The present study models barnyard grass emergence at different flooded rice sowing periods. Furthermore, the effectiveness of the hydrothermal time model in estimating barnyard grass emergence is analyzed. Field emergence was monitored three times a week during two sowing times (October and November) and two growing seasons (2017/18 and 2018/19), in rice sown and unsown areas. Data were converted to cumulative emergence based on total seedlings. Soil temperature and moisture data were used to determine hydrothermal time. The sowing in October led to a continuous emergence of barnyard grass, while the sowing in late November led to different emergence rates. The highest emergence rates of barnyard grass occur in the first sowing time. The hydrothermal time model is adequate to estimate barnyard grass emergence in both sowing times.
Aerial Application Methods for Control of Weed Species in Fallow Farmlands in Texas
Authors: Martin Daniel E. , Latheef Mohamed A. , Lopez Juan D. , Duke Sara E.
Published: November 2020

Prolific growth of weeds, especially when followed by abundant rainfall, is common in Texas farmlands during early winter and progresses into spring when farmers begin chiseling and disking operations for spring-seeded cropping. This research sought to develop aerial application technologies designed to control unwanted vegetation in croplands left fallow until spring. The aerial nozzles used in the study were conventional hydraulic (CP), rotary atomizer, and electrostatically (ES) charged nozzles. Glyphosate at 0.4145 kg ae·ha−1 was applied on weeds using a fixed-wing aircraft equipped with various aerial nozzles used as treatments. The spray application rate for the conventional and rotary atomizer nozzles was 28.1 L·ha−1, while that for the ES charged nozzle was 9.4 L·ha−1. Aerial and ground-based remote sensing and visual estimates quantified weed vigor and canopy health. Both the CP and rotary atomizer nozzles were efficacious in suppressing weeds. ES charged on nozzles at one-third of the spray application rate of the CP and the rotary atomizer nozzles were equally effective in reducing weed vigor. More aerially applied replicated field research trials conducted over time and space are needed to unravel the differences between aerial spray nozzle technologies for controlling weed populations in Texas farmlands.
Indoor Farming Marjoram Production—Quality, Resource Efficiency, and Potential of Application
Authors: Wittmann Sabine , Jüttner Ivonne , Mempel Heike
Published: November 2020

Indoor vertical farming offers great opportunities regarding a sustainable and consistent production of high-quality herbs and raw materials all year round for the perfume, chemical, or food industry. Cultivation takes place in an enclosed structure, operating predominantly independent from external conditions in multi-layer systems equipped with artificial lighting, enabling extremely high resource use efficiencies with a simultaneous increase in yield. On the other hand, field production in terms of plant quality and harvesting times is highly influenced by environmental conditions, making it difficult to maintain homogenous raw material qualities throughout the year. To show how different light qualities affect the overall efficiency and quality of Origanum majorana grown in an indoor farm, the resource consumption, yield, and cultivation time as well as the essential oil quantity was analyzed, and the efficiencies in terms of energy and land use efficiency calculated. The experimental setup clearly demonstrated that the yield regarding fresh as well as dry matter and oil content was comparable to one square meter of open field production. Based on this, the multi-layer system and the noticeable lowered growth period result in a significantly higher area efficiency compared to the open field, leading to a potential increase of annual yields of dried leave weight and oil contents by up to 21 times. It was also shown that a white spectrum (W) showed similar influence on plant growth and yield as a spectrum consisting of blue and red (B/R). Nevertheless, the LED treatment W did show higher light use efficiencies as well as a better working conditions inside the cultivation chamber. By an integration of indoor vertical farming into existing industrial processes, new and innovative opportunities for a flexible and low-risk supply chain seem feasible and according to German food industry meet the interests of existing stakeholders.