bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental and FEM study of surface modification of nickel-based superalloy subjected to ultrasonic surface rolling process
Authors: Yu Weiwei , Wu Jie , Li Yugang , An Qinglong , Ming Weiwei , Chen Dong , Wang Haowei , Chen Ming
Published: February 2023

GH4169 superalloy is widely used in the manufacture of key components such as high-pressure turbine disks, turbine blades and combustion chambers of gas turbines and aero-engines. However, mechanical and metallurgical properties of the surface layer have changed significantly on account of the cutting process, which is easy to cause fatigue failure. Therefore, surface strengthening of GH4169 superalloy subjected to ultrasonic surface rolling process (USRP) is investigated, involved with the mechanical properties and microstructure of the surface layer. The findings demonstrate that the USRP treatment reduces the surface roughness of the basis sample by 93% (from 1.17 µm to 0.08 µm). The USRP treatments improve the degree of the grain refinement, the number proportion of low angle grain boundaries and dislocation density. The depth of residual compressive stress layer and hardened layer of the samples subjected to USRP treatment are improved to 0.6 mm. Moreover, finite element models are utilized to aid in the research of the USRP treatment, especially the stress and strain fields.
Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS
Authors: Aly Amr , Laszlo Zsofia I. , Rajkumar Sandeep , Demir Tugba , Hindley Nicole , Lamont Douglas J. , Lehmann Johannes , Seidel Mira , Sommer Daniel , Franz-Wachtel Mirita , Barletta Francesca , Heumos Simon , Czemmel Stefan , Kabashi Edor , Ludolph Albert , Boeckers Tobias M. , Henstridge Christopher M. , Catanese Alberto
Published: February 2023

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease mainly affecting upper and lower motoneurons. Several functionally heterogeneous genes have been associated with the familial form of this disorder (fALS), depicting an extremely complex pathogenic landscape. This heterogeneity has limited the identification of an effective therapy, and this bleak prognosis will only improve with a greater understanding of convergent disease mechanisms. Recent evidence from human post-mortem material and diverse model systems has highlighted the synapse as a crucial structure actively involved in disease progression, suggesting that synaptic aberrations might represent a shared pathological feature across the ALS spectrum. To test this hypothesis, we performed the first comprehensive analysis of the synaptic proteome from post-mortem spinal cord and human iPSC-derived motoneurons carrying mutations in the major ALS genes. This integrated approach highlighted perturbations in the molecular machinery controlling vesicle release as a shared pathomechanism in ALS. Mechanistically, phosphoproteomic analysis linked the presynaptic vesicular phenotype to an accumulation of cytotoxic protein aggregates and to the pro-apoptotic activation of the transcription factor c-Jun, providing detailed insights into the shared pathobiochemistry in ALS. Notably, sub-chronic treatment of our iPSC-derived motoneurons with the fatty acid docosahexaenoic acid exerted a neuroprotective effect by efficiently rescuing the alterations revealed by our multidisciplinary approach. Together, this study provides strong evidence for the central and convergent role played by the synaptic microenvironment within the ALS spinal cord and highlights a potential therapeutic target that counteracts degeneration in a heterogeneous cohort of human motoneuron cultures.
Assess the public awareness, knowledge, and attitude towards Alzheimer's disease in Medina Saudi Arabia
Authors: ALLUQMANI MAJED , Zahid Heba M. , Alhussaini Ameerah R. , Bokhari Omar K. , Alharbi Samirah S , Aljohani Asmaa R. , Almalki Dalia S , Alahmadi Atheer M.
Published: February 2023

Background There is an increasing number of individuals with dementia due to the rapid aging process worldwide. AD is a major public health problem and the most prevalent form of dementia. It affects mainly older people and causes a significant decline in cognitive abilities, thus affecting the quality of life and independence. Understanding AD is fundamental for early diagnosis and reducing caregiver burden. Aim and objective to assess the public awareness, knowledge, and attitude toward AD in Medina City, Saudi Arabia. Methods A cross-sectional study of a convenient sample from Madina city, Saudi Arabia collected via validated Arabic face-to-face interviews conducted in shopping malls in Al-Madina city, KSA from August 2022 to September 2022. This study included only Madina's residents, between the age of 20 and 65. Data collected via the interview included sociodemographic, knowledge, and attitude towards Alzheimer’s disease. Results The study included 391 participants with a mean age between 18–29 years. The majority of the participants were able to identify aging and AD as causes of memory loss (86.2% and 65.7%) respectively. The overall AD knowledge was measured out of 12 points given to correct responses to the marked questions in table 2. The mean knowledge level was 7 ± 2 out of 12 possible points. Simple linear regression models were performed for the following predictors: age group, gender, and educational level. Data showed that only age groups (B = -0.351, SE = 0.103 (95% CI: -0.553 to -0.149), p < 0.001, R2 = 0.029), predicted the total awareness level related to AD (Table 3). 72.4% of the participants believed that Alzheimer’s patients are not capable of making decisions. Furthermore, 83.4% believe that Alzheimer’s patients need continuous monitoring and 70.8% think they may cause a psychological or societal burden. Conclusion Knowing the signs and symptoms of AD can allow clinicians to early diagnoses, treatment, preventing complications and decreasing the burden on families. So, it's important to guarantee enough public awareness of AD and the importance of managing risk factors that can minimize the risk of AD.
Wave blocking and Bragg resonance in two-layer fluid with current and surface tension.
Authors: Aggarwal Akshita , Mohanty S. K. , Martha S.C.
Published: February 2023

In the present work, the scattering of water waves by undulating bottom in a two-layer fluid system is investigated by the inclusion of current, surface tension and interfacial tension to better understand the phenomenon of wave blocking. The perturbation technique followed by the Fourier transform method is applied to solve the coupled boundary value problem. The associated velocity potentials, Bragg reflection coefficients, and Bragg transmission coefficients are obtained in integral forms. A particular case of the undulating bottom, namely sinusoidal bottom undulation, has been taken into consideration for showing the effects of current speed and surface tension. A shift in the Bragg resonant frequency is observed with a change in the current speed. Further, the combined effects of Bragg resonance and wave blocking are investigated. For some values of opposing current, the group velocity vanishes at two distinct points in the frequency space; the maxima is known as the primary blocking point and the minima is called as the secondary blocking point. For each frequency, there exist three propagating modes between these two blocking points. Certain abnormalities and a sharp increase in the Bragg reflection and transmission coefficients are caused by the superposition of various propagating wave modes and triad interaction within the blocking points as well as a change in the incident wave mode.
Mathematics Subject Classification: 76B15, 42A38, 35Q35.
Lipofuscin, amyloids, and lipid peroxidation as potential markers of aging in Daphnia
Authors: Lowman R. L. , Yampolsky L. Y.
Published: February 2023

Accumulation of autofluorescent waste products, amyloids, and products of lipid peroxidation (LPO) are important hallmarks of aging. Until now, these processes have not been documented in Daphnia, a convenient model organism for longevity and senescence studies. We conducted a longitudinal cohort study of autofluorescence and Congo Red (CR) fluorescent staining for amyloids in four clones of D. magna. Additionally, we used a single time point cross-sectional common garden experiment within a single clone in which autofluorescence and BODIPY C11 fluorescence were measured. We observed a robust increase in autofluorescent spots that show diagnostic co-staining by Sudan Black indicating lipofuscin aggregates, particularly in the upper body region. There was also a significant clone-by-age interaction indicating that some genotypes accumulated lipofuscins faster than others. Contrary to predictions, CR fluorescence and lipid peroxidation did not consistently increase with age. CR fluorescence demonstrated a slight non-monotonous relationship with age, achieving the highest values at intermediate ages, possibly due to elimination of physiological heterogeneity in our genetically uniform cohorts. LPO demonstrated a significant ovary status-by-age interaction, decreasing with age when measured in Daphnia with full ovaries (late phase ovarian cycle) and showing no significant trend or slight increase with age when measured during the early phase in the ovarian cycle.
KIF23, under regulation by androgen receptor, can promote the deterioration of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway
Authors: Xu Hongbo , Liu Jingjing , Zhang Yajun , Zhou Yan , Zhang Lei , Kang Jia , Ning Can , He Zelai , Song Shilong
Published: February 2023

Our study aimed to explore the potential mechanisms of KIF23 regulating function in the progression of nasopharyngeal carcinoma and pinpoint novel therapeutic targets for the clinical treatment of nasopharyngeal carcinoma patients. The mRNA and protein level of KIF23 in nasopharyngeal carcinoma was measured using quantitative real-time PCR and western blot. The influence of KIF23 on tumor metastasis and growth in nasopharyngeal carcinoma was determined through the in vivo and in vitro experiments. The regulatory mechanisms of KIF23 in nasopharyngeal carcinoma were illustrated in the chromatin immunoprecipitation assay. KIF23 was found to be overexpressed in nasopharyngeal carcinoma samples, and its expression was associated with poor prognosis. Nasopharyngeal carcinoma cell’s proliferation, migration and invasion potential could be improved by inducing KIF23 expression both in vivo and in vitro. Androgen receptor (AR) was found to bind to the KIF23 promoter region directly and enhance KIF23 transcription. Furthermore, KIF23 could accelerate nasopharyngeal carcinoma deterioration via activating the Wnt/β-catenin signaling pathway. AR/KIF23/ Wnt/β-catenin pathway promotes nasopharyngeal carcinoma deterioration. Our findings could serve as a new therapeutic strategy for nasopharyngeal carcinoma in the clinical practice.
Decreased expression of prolyl hydroxylase 1 is associated with poor prognosis in colorectal cancers
Authors: Melling Nathaniel , Grass Julia , Reeh Matthias , Tachezy Michael , Blessmann Marco , Nickel Felix , Hackert Thilo , Grupp Katharina
Published: February 2023

Background
Prolyl hydroxylase 1 (PHD1) is a prognostic marker in several cancers.
Aims and scopes:
This study was undertaken to elucidate the clinical relevance of PHD1 in colorectal cancer (CRC) prognosis.
Materials and methods
We compared PHD1 expression on a tissue microarray (TMA) containing samples from 1800 CRCs with corresponding clinicopathological tumor variables and patient survival.
Results
While PHD1 staining was always high in benign colorectal epithelium, high PHD1 staining was detectable in only 71.8% of CRCs. Low PHD1 staining was associated with advanced tumor stage (p = 0.0101) and shortened overall survival in CRC patients (p = 0.0011). In a multivariable analysis including tumour stage, histological type and PHD1 staining revealed tumour stage and histological type (p < 0.0001 each), but also PHD1 staining (p = 0.0202) to be independent prognostic markers for CRC.
Conclusions
In our cohort, loss of PHD1 expression independently identified a subset of CRC patients with poor overall survival and might, thus, be a promising prognostic marker. PHD1 targeting may even allow for specific therapeutic approaches for these patients.
Surface family interpolating a common spherical indicatrix curve
Authors: Bayram Ergin , Güler Fatma , KASAP Emin
Published: February 2023

The trajectory of a moving particle in space forms a curve. By moving a line along a curve, a surface called ruled surface is obtained. The striction point on a ruled surface is the foot of the common normal between two consecutive generators or ruling. The set of striction points defines the striction curve. In the present paper, we obtain surfaces passing through the spherical indicatrix curves formed on the unit sphere by the end points of the geodesic Frenet frame formed on this curve. We present conditions for these curves to be asymptotic curves or geodesic on the surface. We illustrate the method with several examples.
Dyes degradation using atmospheric pressure dielectric barrier discharge pencil plasma jet
Authors: Rathore Vikas , Pandey Akanksha , Patel Shruti , Dave Heman , Nema Sudhir Kumar
Published: February 2023

The dye degradation efficacy of the cold plasma pencil jet is presented in the present investigation. Air plasma is produced in the cylindrical coaxial dielectric barrier discharge configuration. Electrical characterization of plasma is performed and the plasma species are identified using optical emission spectroscopy. For the dye degradation study using air plasma, six different types of dyes (erythrosine, metanil yellow, sudan I, crystal violet, rhodamine B, and Indigo) are chosen. The degradation of dyes is analyzed using UV visible spectroscopy, total organic carbon, and chemical oxygen demand. The results showed complete degradation of all the dyes in UV visible analysis with minimum time for indigo (3 minutes) and maximum time for erythrosine (45 minutes). Moreover, erythrosine (k = 1.08 mg L-1 min-1) and sudan I (k= 3.46 mg L-1 min-1) follows zero-order degradation kinetic and metanil yellow (k = 0.094 min-1), crystal violet (k = 0.25 min-1), rhodamine B (k = 0.17 min-1), Indigo (k = 0.81 min-1) follows first-order degradation kinetics. Also, substantial enhancement in mineralization and reduction in chemical oxygen demand of all the dyes occurs after plasma treatment. The toxicity of plasma degraded dye solution toward freshwater algae species (Chlorella Sorokiniana and Chlorella Pyrenoidosa) are significantly low compared to virgin dyes solutions. The study reveals that pencil plasma jet substantially degrade dyes as well as converts the dyes solutions non-toxic.
Examining the HAP+ Fe2O3 Response in the Magnetic Field, Radiation Protection and Mechanical Properties
Authors: Malidarre Roya Boodaghi , Akkurt Iskender , Korkmaz Abdul Vahap , Ekmekci Ismail
Published: February 2023

HAP (Hydroxyapatite) bio-composite has been used extensively to repair and replace bone and teeth tissues in the human body. However, because of the poor mechanical features of HAP bio-composites, significant enhancements in the strength and toughness of pure HAP have been achieved by the insertion of various alloys and materials into HAP. Accordingly, the present study evaluates the radiation shielding and mechanical features of the Fe2O3 -reinforced HAP composite as an implant for 0.0, 2.5, 5.0, and 7.5 wt.% Fe2O3. Also, the composite response in a magnetic field has been investigated. Employing FLUKA Monte Carlo Code, radiation shielding factors are obtained. In addition, the mechanical characteristics of the studied composites are evaluated using the theoretical method. Findings reveal that increasing the Fe2O3 contents in HAP bio-composite enhances the preferred samples’ radiation shielding and mechanical qualities. Furthermore, in the absence of a magnetic field, the particles' spatial map exhibits symmetric behavior along the x-axis, however, a different trend is observed in the presence of a magnetic field with a value of Bx=5 microT.
WORLD EXPERIENCE OF INDIVIDUAL INCOME TAXATION AND REALITIES OF TAXATION IN UKRAINE
Authors: Oleksich Zh. , Ovcharova N. , Horodetska M.
Published: February 2023

Currently many of the problems that foreign countries have to solve in relation to the transformation processes which affect the financial stability of their economies are similar in nature to the problems that exist in Ukraine. Therefore, studies of foreign practices of personal income taxation are extremely relevant.
The article analyzes the experience of foreign countries in the field of personal income taxation and presents the author's views on the possibility of its implementation in domestic tax practice. Methods of personal income taxation in different countries of the world are considered.
The experience of foreign countries in the taxation of personal income is rich in positive examples. The analysis showed that the lowest income tax rates are characteristic of countries with lower rates of economic development and usually without the use of progressive taxation. High - inherent in the developed due to the presence of a progressive scale of taxation, which allows you to shift the tax burden from the poorer to the more affluent.
Therefore, one of the priority areas in the development of tax policy in Ukraine should be its gradual socialization, which focuses not only on the fiscal function of the tax, which leads to increased tax revenues to the budget of Ukraine, but also the social function of the tax aimed at universal values.
The main direction of further improvement of the domestic legal framework in this area should be to reduce the tax burden on socially vulnerable groups and increase the responsibility of taxpayers for tax evasion. One of the priority areas in the development of tax policy in Ukraine should be its gradual socialization, which focuses not only on the fiscal function of the tax, which leads to increased tax revenues to the budget of Ukraine, but also the social function of the tax aimed at universal values. The practice of taxation of individuals in foreign countries cannot be an absolute basis for copying taxation in Ukraine.
Learning knot invariants across dimensions
Authors: Craven Jessica , Hughes Mark , Jejjala Vishnu , Kar Arjun
Published: February 2023

We use deep neural networks to machine learn correlations between
knot invariants in various dimensions. The three-dimensional invariant
of interest is the Jones polynomial J(q)J(q),
and the four-dimensional invariants are the Khovanov polynomial
\text{Kh}(q,t)Kh(q,t),
smooth slice genus gg,
and Rasmussen’s ss-invariant.
We find that a two-layer feed-forward neural network can predict
ss
from \text{Kh}(q,-q^{-4})Kh(q,−q−4)
with greater than 99%99%
accuracy. A theoretical explanation for this performance exists in knot
theory via the now disproven knight move conjecture, which is obeyed by
all knots in our dataset. More surprisingly, we find similar performance
for the prediction of ss
from \text{Kh}(q,-q^{-2})Kh(q,−q−2),
which suggests a novel relationship between the Khovanov and Lee
homology theories of a knot. The network predicts
gg
from \text{Kh}(q,t)Kh(q,t)
with similarly high accuracy, and we discuss the extent to which the
machine is learning ss
as opposed to gg,
since there is a general inequality |s| ≤2g|s|≤2g.
The Jones polynomial, as a three-dimensional invariant, is not obviously
related to ss
or gg,
but the network achieves greater than 95%95%
accuracy in predicting either from J(q)J(q).
Moreover, similar accuracy can be achieved by evaluating
J(q)J(q)
at roots of unity. This suggests a relationship with
SU(2)SU(2)
Chern—Simons theory, and we review the gauge theory construction of
Khovanov homology which may be relevant for explaining the network’s
performance.
Dynamics of Aleurocanthus woglumi Ashby (Hemiptera: Aleyrodidae) in Tahiti acid lime (Citrus latifolia) orchards under different fertilizer applications
Authors: Gomes Alirya Magda Santos do Vale , Lemos Raimunda Nonata Santos de , Lopes Gislane da Silva , Carvalho Cristina Silva , Reis Fabrício de Oliveira , Araujo José Ribamar Gusmão , Mondego Janaina Marques , Amaral Ester Azevedo do , Rêgo Adriano Soares
Published: February 2023

Citrus black fly Aleurocanthus woglumi Asbhy is an important citrus pest because it causes significant losses in production. The objective of this study was to evaluate the incidence and distribution of A. woglumi egg laying, eggs and nymphs on Citrus latifolia (Tahiti acid lime) plants grown under different fertilizer applications. The experiment was carried out in a citrus orchard in the municipality of Paço do Lumiar, MA, Brazil. A randomized block design in a 3×5×3 factorial arrangement (three evaluation times, five treatments, and three plant strata) was used with 4 replications. The experimental unit consisted of three plants and treatments with different fertilizations were applied to the soil: T1: control (no fertilizer application); T2: organic fertilizer (bovine manure); T3: organic fertilizer + potassium silicate (K2O3Si); T4: NPK; T5: NPK + K2O3Si. The number of egg laying, eggs and nymphs of A. woglumi was evaluated in the basal, mid and apical strata of C. latifolia plants at 30, 60 and 90 days after fertilizer application. Reductions in the number of eggs and nymphs were observed in treatments with organic fertilization + K2O3Si and NPK + K2O3Si. Citrus latifolia plants treated with K2O3Si were less susceptible to A. woglumi and plants fertilized with NPK present higher susceptibility (p<0.05). There was a higher incidence of egg laying, eggs and 1st instar nymphs in the apical stratum and 2nd, 3rd and 4th instar nymphs in the basal and mid strata in C. latifolia (p<0.05). The addition of K2O3Si to organic and mineral fertilization is recommended as a viable alternative to reduce the population level of A. woglumi in citrus plants
Influence of precipitation on reproductive phenophases in Moringa oleifera Lam
Authors: Junior João Luciano de Andrade Melo , Melo Luan Danilo Ferreira de Andrade , Neto João Correia de Araújo , Silva Keven Willian Sarmento Galdino da , Soares Larice Bruna Ferreira , Ferreira Vilma Marques , Paes Reinaldo de Alencar , Costa Jaqueline Figueredo de Oliveira , Silva Ivanildo Claudino da , Souto Priscila Cordeiro , Chaves Lívia Francyne Gomes
Published: February 2023

Phenology works as an indicator of the response of plants to local climatic and edaphic conditions, enabling a better understanding of the dynamics of the species. The seasonal climate also influences the occurrence of periodic rhythms of growth and reproduction (phenophases). Moringa oleifera Lam., belong to the Moringaceae family, is widely distributed in tropical countries and easily adapts to semiarid conditions, having medicinal value as a forage, flavoring, in the cosmetics, honey, fuel and in the treatment of water purification through the coagulant solution made from the seeds. The objectives of the present work were to study the phenological behavior of M. oleifera and to relate the variations in phenophases with climatic factors, precipitation and temperature. For collection of phenological data, ten trees were selected, and the records were carried out between the first half of August 2020 and the first half of July 2021. The observations were carried out at fortnightly intervals, recording the presence and absence of the flowering and fruiting phenophases including flowering – period in which the tree is in full flowering; fructification – which starts from the moment that small fruits are visible after the fertilization of the flowers and ends with the dispersal of seeds. The Fournier intensity index was determined using a semiquantitative interval scale of five categories (0 to 4), with an interval of 25% between each category. The phenological data of intensity of each phenophase (flowering and fruiting) were related to precipitation and average temperature fortnightly using Spearman's correlation. The flowering and fruiting phenophases of M. oleifera intensified in August, September and December 2020, showing Fournier intensity peaks of 47.5 and 77.5, 72.5 and 92.5, and 35 and 55 %, respectively, and April and June 2021, in the monthly intervals of greater rainfall, with percentage rates of 82.5 and 95, 77.5 and 80%, respectively. In general, we found that M. oleifera produced seeds between the first half of August and the first half of September, and the second half of December 2020, and the second half of April and the first half of June 2021. Thus, it can be stated that the production of fruits by M. oleifera is interrupted in the months with less rainfall (October to November 2020, and January to February 2021). The intensity and duration of the flowering and fruiting phenophases in M. oleifera are synchronized with the temporal distribution of the precipitation pulses in that habitat
How does green HRM influence environmental and social sustainability in hotels?
Authors: Abbas Zuhair , Smaliukienė Rasa , Zamečnik Roman , Kalsoom Ghulam , Cera Elona
Published: February 2023

Green human resource management (GHRM) is bringing positive transformations in business and society, as well as challenges for hotels. Drawing from social cognitive theory (SCT), this study examined green HRM with environmental and social performance. Significantly, this paper also used organizational green culture as a mediation variable. This empirical study employed a quantitative research method. Data were collected from 155 employees working in Pakistan’s hotels. The results demonstrate that green HRM (t-statistic value = 9.676, p-value = 0.000) is positively related to organizational green culture. In addition, organizational green culture (t-statistic value = 11.254, p-value = 0.000, t-statistic value = 16.882, p-value = 0.000) has a significant effect on environmental and social performance. Moreover, organizational green culture fully mediated the relationship between green HRM and environmental performance (t-statistic value = 5.444, p-value = 0.000). Finally, organizational green culture fully mediated the relationship between green HRM and social performance (t-statistic value = 7.218, p-value = 0.000).
AcknowledgmentThis work is partially funded under FaME TBU No. IGA/FaME/2023/012 “Closed and open innovations: role of human resource, servant leadership, digitalisation, and uncertainty.” Authors would like to thank Prof. Rasa Smaliukienė for partially funding this research. This work also acknowledged Grant No.FSR-FORD 5-6/2022-23/FaME/006 “Linking stakeholder pressure, green HRM application and competitive advantage in the hotel industry.”
3,5-Di-Tert-Bütil-2-Hidroksibenzaldehit Bileşiğinin Kimyasal Aktivite ve Spektroskopik Çalışmaları
Authors: GÜZEL Enis , MACİT Mustafa , ERGÜZELOĞLU Ebru , YAVUZ Metin
Published: February 2023

Başlıkta belirtilen ve önceden tek kristal X-ışını kırınım, IR ve 1H-NMR çalışması deneysel olarak yapılmıştır. Bu çalışmada daha önceden yapılan çalışmalar ile birlikte, X-ışını kırınımı, FT-IR, UV-Vis, 13C-NMR ve 1H-NMR çalışmaları gerçekleştirilmiştir. Spektroskopik verilerden elde edilen sonuçlar teorik olarak elde edilen sonuçlar ile birlikte tartışılmıştır. Moleküler yüzey morfolojisi hakkında bilgi ve görsel elde etmek için Hirshfeld yüzey analizi kullanılmıştır. Moleküler yapı içerisinde bulunan atomların aralarındaki etkileşimleri elde etmek için 2-D(2-boyutlu) parmak izi grafikleri üretilmiştir. Başlık bileşiği için 1H-NMR ve 13C-NMR kimyasal kaymaları hesaplanmıştır. Ek olarak, araştırılan bileşiğin optik özellikleri araştırılmıştır. Kimyasal aktivite parametreleri olarak bilinen sertlik ve yumuşaklık hesaplamaları molekül için hesaplanmıştır. Son olarak, araştırmanın zenginliğinin artması amacıyla en yüksek dolu moleküler orbital-en düşük boş moleküler orbital (HOMO-LUMO) çalışmaları gerçekleştirilmiştir.
Tripodal Schiff Base Compounds Containing Triazole and Mn3+ and Fe3+ Complexes: Synthesis, Characterization, and Investigation of Their Spectral Properties
Authors: BAL Mustafa , KÖSE Ayşegül
Published: February 2023

In this study, it was aimed to synthesize and elucidate the structure of tripodal Schiff bases, which are used in the fields of materials science, chemistry, and pharmacology, and especially for the synthesis of chemical sensor materials due to their very good tendency to form complexes with metals. For the synthesis of new Schiff base tripodal compounds and their complexation with metals; Tripodal compound was synthesized as a result of the reaction of 2-hydroxy-4-(prop-2-yn-1-yloxy) benzaldehyde and N1, N1-bis(2-aminoethyl) ethane-1,2-diamine. The obtained compounds were complexed with Fe3+ and Mn3+ metals. The structures of synthesized tripodal ligands and metal complexes were tried to be elucidated using IR, UV-vis, Photoluminescence, 1H-NMR, 13C-NMR spectroscopic methods.
Gıda ve Genom İnteraksiyonu: Beslenme Genomiği
Authors: ÇETİN Bülent , AKTAŞ Haktan
Published: February 2023

Beslenme ile sağlıklı yaşam arasındaki ilişki çok uzun zamandır bilinmektedir. Bu ilişkinin temelini oluşturan beslenme genomiği alanı son yıllarda oldukça fazla dikkat çekmektedir. Genomik, proteomik, transkriptomik, metabolomik, epigenomik gibi “omik” teknolojileri ile yakından ilişkili olan beslenme genomiği, gıda bileşenlerinin gen ekspresyonunda oluşturabilecekleri değişiklikleri ve insan vücudunun bu gıda bileşenlerine verebileceği yanıtları incelemektedir. Gıdalar, özellikle DNA metilasyonu, histon modifikasyonları ve kodlamayan RNA gibi mekanizmalarla doğrudan genomun işleyişini etkilemektedirler. Bunların yanında, çölyak, nörodejeneratif rahatsızlıklar, obezite, diyabet, laktoz intolerans, fenilketonüri ve kanser gibi hastalıklar da dolaylı olarak beslenme ile yakından ilişkilidir. Beslenme genomiği alanı gelişim aşamasında olduğundan dolayı, beslenme-sağlık mekanizmasının tam olarak ortaya konulabilmesi için daha fazla çalışmaya ihtiyaç duyulmaktadır.
Assessment of the feasibility of establishing financial slack in a company: The model and its empirical verification
Authors:   HSE University, Berezinets Irina V. , Nikulin Egor D. ,   St. Petersburg State University, Okulov Vitaly L. ,   St. Petersburg State University
Published: February 2023

Financial slack refers to excessive financial resources of a company that exist in addition to those that are necessary for operating activities. Is it feasible for a company to create financial slack? The answer to this question is ambiguous. On the one hand, the existence of slack provides a company with resources that can be used, for example, in case of financial constraints or for investing. On the other hand, the creation of financial slack means that the underlying cash reserves cannot be used for other purposes, for example, for distribution to stockholders. The paper presents the model for valuing a company’s financial slack that builds on the investment motive for forming the slack. The slack itself is considered to be a real option. The proposed model stipulates the conditions under which the creation and storage of financial slack is expedient. Those conditions are determined by the current value of business as well as by its riskiness. The empirical verification of the model was conducted by using the sample of 180 Russian public companies, the shares of which were traded in 2012–2019. The study confirmed that the return on financial slack in the current period will be higher specifically for those companies which were recommended to form financial slack in the prior period according to the proposed theoretical model.
Dikaiopolis in Despair (Aristophanes’ Acharnians 30–31)
Authors:   A. M. Gorky Institute of World Literature of the Russian Academy of Sciences, Nikolsky Boris M.
Published: February 2023

The article deals with a passage from the prologue of Aristophanes’ Acharnians, vv. 30–31. Close reading of the passage and analyzing each verb of the series in vv. 30–31 shows that the entire series of verbs in Acharnians 30–31 describes Dikaiopolis’ suffering and constitutes the culmination of the woes listed in his monologue. This last and greatest of his woes cannot be mere annoyance at having come first to the Pnyx and not knowing how to kill time. στένω must mean a lament tragic in tone, and κέχηνα intensifies this vocal lament though adding a comic bathos. σκορδινῶμαι does not refer here to drowsy stretching as it is usually interpreted by scholars but to convulsions of rage and despair. πέρδομαι indicates acuteness and intensity of Dikaiopolis’ disappointment; the relationship between σκορδινῶμαι and πέρδομαι is similar to that between στένω and κέχηνα, where the second verb emphasizes and marks the culmination of the first (“I’m moaning so much that my mouth is open wide” and “I’m convulsed to the point of farting”). παρατίλλομαι must mean “to tear out the hair on one’s head”, a gesture that is obviously a sign of sorrow and despair. The verbs γράφωand λογίζομαι describe Dikaiopolis writing out and assessing his debts sitting in the assembly place. The lines that follow are tightly connected to 30–31 and explain the reason for the protagonist’s despair: Dikaiopolis dreams of the countryside and hates the city, but due to the war cannot return to the country (32–33); his hatred of the city is further explained by the enormous expenses city life entails.
Were Homeric Glosses Part of School Education in Fifth-century Athens? New Interpretation of Aristophanes’ Daitales fr. 233
Authors:   A. M. Gorky Institute of World Literature of the Russian Academy of Sciences, Chepel Elena Yu.
Published: February 2023

The article revisits Aristophanes’ Daitales fr. 233 which is often taken as (the only) evidence of Homeric glosses being drilled by Athenian youth as part of their school education in 5th c. BC. The author discusses in detail the context of Aristophanic citation in Galen’s work, the state of the text of the fragment and its modern interpretations. In fact, nothing in the text itself directly suggests that learning glosses was part of the traditional school education in Athens. On the contrary, it can be argued that Aristophanes presented glosses as linguistic innovations and intellectuals studying them as sophists. The parallels between Daitales and Clouds, as well as Plato’s Kratylos and other fifth-century texts must be taken into account when interpretingthe dialogue between the Father and his Son in fr. 233. As a conclusion, the author suggests that the characters of Daitales should be interpreted differently: the Old Man in this episode of the play is not opposing the sophistic teachings, but rather using these in his argument as an instrument to demonstrate the Licentious Son his ignorance. The latter is apparently not a follower of the sophists and defends himself with his more practical knowledge of legal terms.
Antiphon in the New Millennium
Authors:   St. Petersburg State University, Takhtajan Souren A.
Published: February 2023

This paper is an overview — in it I take a critical look at works that have come out in recent years about Antiphon. My primary focus is on four books: two scholarly works on Antiphon, one by Annie Hourcade and another by Michael Gagarin, an edition of the fragments of Antiphon’s treatises with a detailed commentary by Gerard Pendrick, and, finally, a new edition of Antiphon’s speeches prepared by Mervin Dilts and David Murphy. There is still a dispute among scholars about the authorship of the Corpus Antiphonteum. Some (the separatists) consider that there were separate authors for the speeches, on the one hand, and for the treatises, on the other — Antiphon the orator and Antiphon the sophist, respectively. Others (the unitarians) insist that there was a single author for both the speeches and the treatises. In the 19th and the first half of the 20th centuries, the separatists had the upper hand, but the situation slowly began to change, and now most scholars — rightly so in my opinion — argue for a single authorship. The separatists are compelled to divide the biographical testimonies of Antiphon between the orator and the sophist. But in the case of a single Antiphon, it turns out there is more than a little information about that person. In this paper, I present a review of scholarly opinion about evidence according to which Antiphon invented τέχνη ἀλυπίας and opened a psychotherapeutic clinic, where he tried to help his patients using verbal therapy. Some scholars call the tradition of the clinic into question. The separatists attribute any evidence about it to Antiphon the sophist. Like other scholars, I uphold the credibility of the clinic. I also take a look at the image of Antiphon presented by Xenophon (Mem. 1, 6.). Many scholars consider Xenophon’s story to be fictitious or reject it outright. The separatists believe that Xenophon calls Antiphon a sophist in the very first sentence of the sixth chapter in order to distinguish him from his namesake, Antiphon the orator. I think Xenophon’s goal is different. Socrates,in conversation with Antiphon during their second meeting, which Xenophon describes later on in the same chapter, likens sophists to πόρνοι (Mem. 1. 6. 13). Obviously, Xenophon calls Antiphon a sophist because he intends that the shameful implications of this comparison be applied first and foremost to him. Hourcade and Gagarin want to show that the author of the treatises and the speeches was one and the same person. Even though Pendrick is a separatist, the parallels he draws between the fragments of the treatises and individual passages in the speeches also, I think, favor the idea of a single Antiphon. I conclude that, thanks to the workof these scholars, Antiphon has, although not yet fully, been put back together again.
An Employment Law Study of the Interaction of Personnel and State Policies in the Digital Age
Authors:   Ural State Law University named after V. F. Yakovlev, Serova Alena V.
Published: February 2023

The author considers the theoretical foundations of the interaction of personnel and state policies in terms of digitalization of the world of work. This goal is achieved by solving the following tasks: studying the concepts of "personnel policy" and "state policy"; studying of their stages of implementation; highlighting and researching certain aspects of the interaction of personnel and state policies in the digital age; formulation and substantiation of political and legal proposals. The research methodology is based on systemic and political-legal approaches. The main results of the study are as follows. The systemic-structural and substantive aspects of the interaction of personnel and state policies in the digital age are highlighted and analyzed. The systemic and structural aspect is manifested in the following: personnel policy is a part of the public administration system; the structure of any sectoral state policy always includes a personnel block. From the point of view of the substantive aspect through the implementation of personnel policy, political decisions made by the state are implemented, and employers as subjects of personnel policy using social partnership mechanisms or independently during monitoring of the implementation of state policy can express their opinion regarding identified defects in the implementation of state policy. A feature of this interaction is that not only employers, but also employees, as objects of personnel policy, can also influence the development of state policy in terms of the digitalization of the world of work, for example, through the mechanisms of social partnership. The stages of implementation of personnel and state policies are described, within which they interact with each other. The study also formulated and substantiated political and legal solutions to the problems of machine-readable labor law, replacement of human labor with digital technologies, training and additional professional education of employees.
The balance between constitutional values, rights and legitimate interests as a criterion of constitutionality of restrictions on the freedom of labour
Authors:   Russian State University of Justice — North-Western Branch, Pugacheva Natalia V.
Published: February 2023

The freedom of labour, as a principle which guarantees the right of the citizens to choose their occupation and profession, is fundamental for establishing legal regulation of social relationship in the relevant area. The legislator is obliged to ensure genuine and effective realization of this freedom for citizens, based on equality and prevention of discrimination. At the same time, the freedom of labour is not absolute, since in some spheres it comes across rights and legitimate interests of other individuals as well as public interests, and it inevitably leads to rivalry between rights and freedoms of various parties as well as values protected by the constitution. The mechanism for legal regulation of the relationship emerging while realizing the freedom of labour, which constitutes a combination, inter alia, of law-making and law enforcement, is intended to ensure that rights and legitimate interests of all the participants in this relationship are taken into account. The guidance for efficient accommodation of rights and legitimate interests of parties (private as well as public ones) in the sphere of labour is given by the Constitution of the Russian Federation which envisages a possibility for restricting constitutional rights and freedoms in general as well as criteria for such restrictions. The federal lawmaker is to strive for such accommodation, and the mechanism of constitutional justice is intended to promote this approach. Therefore, legal regulation of the relationship in this area should respect the balance between constitutional values, rights and legitimate interests, private as well as public ones, and it should be acknowledged as a separate constitutional value which is intended to be a criterion for constitutionality of restrictions on the freedom of labour.
The notion of transactions in labour law and social security law
Authors:   St. Petersburg State University, Diveeva Nelly I. , Nogaylieva Fatima K. ,   St. Petersburg State University
Published: February 2023

The institution of transactions, having gone through a long path of evolution and filling with meanings, has acquired in modern law the quality of a universal means of regulating social relations. The universality and practicality of transactions as a legal means has tangible manifestations in any branch of law, forming, to one degree or another, the distinctive characteristics of the method and mechanism of legal regulation. The essence and place of transactions (and contracts as their varieties) continues to be the subject of discussion, the importance of transactions as legal facts in many industries is underestimated and needs additional scientific analysis. In this article, the authors raise the question of the nature and place of transactions in the system of legal facts, as well as sources of law in labor law and social security law. Using the example of the branches of labor law and social security law, the authors prove that transactions are among the universal general legal means that do not have an exclusively civil law binding. At the same time, the legal regulation of this tool varies from industry to industry. In labor law, the understanding of a transaction as one of the legal means contributes to the formation and development of an employment relationship not as a confrontational relationship, but as a relationship of cooperation, a consensual relationship. Due to the lack of legal equality between the subjects of social security law, their rights and obligations cannot be fully determined by the contract. However, the tendency to expand contractual regulation demonstrates the significant impact of private law on many social security relations (state social assistance, social services, non-state social security).
Employee’s participation in the employer’s affairs: Organizational forms and legal regulation (economic and legal aspects)
Authors:   St. Petersburg State University, Hohlov Evgeny B.
Published: February 2023

Social partnership in the sphere of labour is one of the most important principles underlying the modern mechanism of legal regulation of social and labour relations. The significance of this principle lies in the fact that thanks to its implementation in practice, social peace in the sphere of social work is ensured and, accordingly, social stability in society as a whole. The current Russian labour legislation not only formulates social partnership as a principle of legal regulation of social labour, but also defines the main forms (directions) of implementation of this principle. Currently, the direction of social partnership is most thoroughly regulated in legislation and tested in practice, which can be conditionally defined as representative, when representatives of the main social groups in the field of labour — employees and employers, as well as the state, as the personification of general social interests, enter into a dialogue on issues of public importance and conclude this dialogue with an appropriate agreement. Another area of social partnership, which is usually defined as the participation of employees in the affairs of the employer, is rather poorly regulated in legislation, is very little widespread in practice and is practically ignored in domestic legal science. Meanwhile, as world experience shows, the system of employee participation in the affairs of the employer is a very effective means of ensuring the solution of both social and economic problems. The article analyzes the main aspects of participation. It is based on the employee’s right to participate as a subjective labour right. Its implementation is provided mainly by means of two branches of law — labour and civil (corporate). Accordingly, there are two forms of participation, although related to each other, but having an independent character — economic and organizational. The first is implemented through various options for the participation of employees in the profits and property of the employer, the second — through the participation of employees in management, including self-management of labour collectives of various levels in the structure of the employer’s enterprise.