bluuebunny/crossref_metadata_2025 huggingface dataset:
Module Type Package in der Fertigungsautomatisierung
Authors: Habiger Pascal , Hildebrandt Gary , Drath Rainer , Fay Alexander
Published: November 2023

Das Module Type Package (MTP) stellt Informationen über Module der Prozessautomatisierung standardisiert bereit und erleichtert so deren Integration in eine modulare Anlage. Der MTP-Standard verspricht auch für die  Fertigungsautomatisierung großes Potenzial. Im ersten Beitragsteil, erschienen im atp magazin 9/2023, wurde untersucht, was dem MTP fehlt, um die MTP-Konzepteauf die Fertigungsautomatisierung zu übertragen. Der zweite Beitragsteil stellt ein Konzept zur Umsetzung vor: die Ergänzung des klassischen MTP um fertigungstechnisch-spezifische Informationen. Im Ergebnis soll das  orchestrierende System befähigt werden, unter anderem das Diensteverhalten eines Moduls automatisch zu  erkennen, zu interpretieren und anzuwenden. Durch eine Plugin-Architektur wird die MTP-Datei domänenspezifisch erweitert, ohne den MTP-Standard selbst zu verändern.
Оценка поражения лесов Арктической зоны Красноярского края с помощью вероятностно-графической модели
Authors:   Сибирский федеральный университет, Ефремова И.С. , Мучкина Е.Я. , Тасейко О.В. ,   СибГУ им. М.Ф. Решетнева
Published: November 2023

Экономическое развитие Российской Федерации во многом обусловлено разнообразием природных ресурсов. В последние годы упор делается на малонарушенные экосистемы крайнего севера как источник такого ценного природного ресурса как лес [1]. Однако активное ведение промышленной деятельности наряду с экстремальными природно-климатическими условиями способно изменить биологическое разнообразие Арктической зоны Красноярского края вследствие поражения лесных массивов. Арктическая зона Красноярского края включает в себя земли лесного фонда Борского, Таймырского и Туруханского лесничеств. В качестве базовых индикаторов для оценки нарушения устойчивости лесов Красноярского края выбраны семь неблагоприятных факторов различного происхождения [2]. В Арктической зоне идентифицированы следующие явления: пожары, болезни леса, антропогенное воздействие, непатогенные факторы. Проблема воздействия болезней леса и непатогенных факторов связана с выборочным воздействием на определенную породу древесины. Это значительно усложняет расчет вероятности события классическими способом. Решением проблемы может быть использование вероятностно-графической модели на основе методологии Байесовских сетей. Основная идея построения графической модели заключается в использовании понятия модульности, то есть разложения сложной системы на простые элементы. Для объединения отдельных элементов в систему используются результаты оценки вероятностей, которые обеспечивают состоятельность модели в целом. По результатам проведенных исследований установлено, что лесные экосистемы Арктической зоны Красноярского края подвержены воздействию природных стрессоров гораздо меньше по сравнению с северными регионами края [3]. Наблюдается значительное увеличение вклада промышленных выбросов на состояние древесных культур в таймырском лесничестве. Основной причиной гибели насаждений в Арктической зоне Красноярского края являются лесные пожары – 82% случаев. Остальные показатели распределили между собой непатогенные факторы 13,9 %, антропогенное воздействие 3,8 % и болезни леса 0,3%.
Microneedles — Heterogeneous Intelligent Microsystems for Transdermal Monitoring and Correction of the Body State
Authors:   St. Petersburg State Electrotechnical University ", Testov O.A. ,   LETI",   named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Aivazyan V.M. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Khmelnitskiy I.K. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Luchinin V.V. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Gareev K.G. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Karelin A.M. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Parfenovich S.E. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Testov D.O. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation, Kholodkova E.E. ,   St. Petersburg State Electrotechnical University "LETI" named after V. I. Ulyanov (Lenin), St. Petersburg, 197022, Russian Federation
Published: November 2023

The use of microneedles for discrete and continuous monitoring and correction of the body state is a progressive direction in personalized medicine. The desire to minimize the consequences of invasive diagnostic methods and increase the effectiveness of drug therapeutic effects determines the intellectualization of microneedles, their designs and technologies of use. Microneedles and their arrays are presented as complex functional microsystems, the creation of which is based on the use of micro- and nanote-chnology processes, as well as heterogeneous organic-inorganic compositions.
Digital Participatory Model as Part of a Data-Driven Decision Support System for Urban Vibrancy
Authors: Kırdar Gülce , Çağdaş Gülen
Published: November 2023

Digital participation relies on computational systems as the instruments for expert engagement, data-driven insight, and informed decision-making. This study aims to increase expert engagement with the Bayesian-based decision support model in evaluating urban vibrancy decisions. In this study, urban vibrancy parameters are defined using “economic, use, and image value” measures. This article focuses on the visual aspect of vibrancy, defined as the image value of place. The image value is evaluated through likability and likability features. The case study area is the Eminönü Central Business District in the Istanbul Historic Peninsula due to its distinctive urban dynamics derived from the duality of being a cultural and cosmopolitan city center. This research presents a method as a decision support system (DSS) model based on the Bayesian belief network (BBN) and spatial BBN for supporting urban vibrancy decisions. The spatial BBNs monitor spatial outcomes of variables’ dependencies that form through the BBN relationship network. Spatial BBN tools monitors the spatial impact of decisions for informed urban interventions. The results demonstrate that urban greening, pedestrianization, and human-scaled streetscapes should be prioritized to make streets more likable. The most significant intervention areas are Tahtakale for signboard regulation, Sultanahmet and Vefa for cultural landscape improvement, and Vefa and Mahmutpaşa for planning building enclosures. The participation is achieved by evaluating urban vibrancy with what-if scenarios using BBN. The developed DSS model addresses which parameters should be prioritized, and what are their spatial consequences. The use of spatial BBN tools presents certain limitations in terms of interoperability and user interaction. Overall, this research contributes to participatory urban planning by incorporating both conditional and spatial dependencies. This unique approach not only promotes a more holistic understanding of urban vibrancy but also contributes to the advancement of digital participation in urban planning decisions.
THE ROLE OF BUSINESS PROCESS REENGINEERING (BRP) IN DIGITAL TRANSFORMATION: THE PATH TO EFFICIENCY
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Filuk G. M. , Lisova R. M. ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: November 2023

The article explores the relevance of changes in the modern business environment and the role of Business Process Reengineering (BPR) in achieving competitiveness and digital transformation in enterprises. In the context of increasing competition and market instability, the article presents arguments that changes have become a necessity for organizations, and BPR is a crucial tool for adaptation and achieving strategic goals. The article's objective is to assess the impact of BPR on efficiency improvement and successful implementation of digital transformation in contemporary organizations. The authors employed interdisciplinary research methods, including the comparative method to evaluate modern approaches to BPR in the context of digital transformation. The analysis method was used to determine the influence of BPR on the effectiveness of digital transformations. Systemic and structural analysis methods were utilized to provide an in-depth examination of the structure and components of BPR and to evaluate its impact on complex enterprise systems in the context of digital transformation. The authors emphasize the importance of integrating digital technologies into the BPR process as a means of optimizing business processes and increasing profitability. The benefits of digital transformation are highlighted, but the article also underscores that successful implementation requires careful preparation and the study of innovative approaches. Various types of enterprises that may undertake BPR, including those facing financial challenges, anticipating potential issues, and aiming to stay industry leaders, are discussed. The article explores the relationship between Business Process Reengineering and digital transformation in contemporary organizations, shedding light on BPR's role in data collection and analysis to transform outdated business processes and prepare the organization for digital transformations. The article provides insights into how both approaches can interact to help organizations prepare for successful digital transformation. Common characteristics between BPR and digital transformation are discussed, including their orientation towards innovation and the use of advanced technologies to optimize business processes. The authors emphasize the need for careful preparation and the management of the digital transformation process as a critical strategic initiative for organizations striving for innovation and competitive advantage.
INTERNALLY DISPLACED PERSONS IN THE LABOR MARKET OF UKRAINE: PROBLEMS AND SUPPORT MECHANISMS
Authors:   National University of Water Management and Environmental Engineering, Rivne, Ukraine, Yurchyk Halyna , Samoliuk Natalia ,   National University of Water Management and Environmental Engineering, Rivne, Ukraine
Published: November 2023

The article is devoted to the study of the situation of IDPs and mechanisms of their support both in the general and official labour market. Based on the analysis of quantitative indicators of IDPs in the regional context, the author proves the importance of IDPs as a special segment of labour supply throughout the country. A significant increase in the burden on the registered labour market in terms of IDPs since 2022 has been identified, with a simultaneous decrease in their employment and involvement in other active and passive support programmes. Statistically, the deterioration of the situation of IDPs in the registered national labour market has been proven, especially in the south-eastern regions of the country. Among the existing mechanisms to support IDPs in the registered labour market, universal ones that apply to all unemployed dominate. Special support programmes for IDPs, such as reimbursement of transport costs for relocation to another area for employment, as well as reimbursement of employers' costs for retraining and professional development of IDPs (subject to certain conditions) are only legally enshrined, but are not actually implemented. The programme to facilitate the employment of IDPs by compensating employers for their labour costs is being implemented on a critically small scale nationally. The main strategies implemented by IDPs (including in the labour market) for their own survival were grouped and typified. An important component of IDPs' survival is their behaviour in the labour market in the context of reducing their own requirements and attracting people of retirement age. Statistically, there is a significant decrease in the ability of IDPs to earn income due to the lack of work since 2022. Higher unemployment rates among IDPs in the general labour market are observed in the south of Ukraine and Kyiv region. It is proved that there are no effective mechanisms to support IDPs in the labour market outside the SES. The state policy of supporting IDPs in the labour market is mainly limited to its registered segment and has a predominantly universal focus. The author proves the need to develop and implement targeted programmes to support IDPs in the general labour market through economic policy instruments (including by stimulating social entrepreneurship).
ESSENCE AND CLASSIFICATION OF MODERN PERSONNEL MANAGEMENT TECHNOLOGIES
Authors:   University of Economics and Law ", Kondratiuk Ivan ,   KROK",   , Kyiv, Ukraine
Published: November 2023

The article is devoted to the problems of researching the essence of the currently relevant concept of personnel management technology, and its interrelationship with the concepts of personnel technology, innovative personnel management technology, as well as improving and updating the classification of modern types of personnel technologies. Thus, the article highlights the main principles on which effective personnel management technology should be built. The study of approaches to defining the essence of the concept of "personnel management technology" was carried out, and the features and distinguishing features of the opinions of domestic and foreign scientists regarding the features and understanding of this concept were determined. A proper definition of personnel technology as a modern type of socio-economic technology is proposed. The classification of modern personnel technologies has been improved, as a result of which the following classification groups have been identified: marketing personnel technologies, personnel technologies of labor organization and optimization, personnel technologies of labor adaptation of employees, personnel technologies of loan work, educational personnel technologies, personnel technologies, used in selection and hiring, personnel-technologies of increasing the efficiency of labor use, personnel-technologies of personnel labor control, informational personnel-technologies. It has been established that the potential of existing methods, methods and tools of personnel management is almost exhausted, therefore the search for ways to increase the efficiency of the use of human resources moves to the area of implementation of innovative personnel technologies. It was determined that, despite the diversity of scientific research in the field of personnel management, modern innovative personnel management technologies in domestic companies have implementation problems due to the frequent manifestation of the phenomenon of "resistance to change", the impossibility of accurately calculating the effectiveness of the implementation of innovative technologies in the field of HR, the need to introduce personnel adaptation tools to the specifics of innovations.
The Effect of Menstrual Cups on Sustainable Hygiene Management: Revolutionizing Menstrual Health
Authors: Madhuben Sharma  , Sameeksha Rawat
Published: November 2023

This review article explores the use of menstruation cups to manage period hygiene and promoting environmental sustainability. The primary goal of this paper is to review different types of commonly used menstrual products such as tampons, sanitary pads, reusable cloth pads, menstrual cups, and period underwear, including their affordability, environmental impact, and health effects. Menstrual cups are found out to be a better alternative for managing menstruation because it is reusable, affordable, and does not cause harm to environment and human health. The paper also looks at how menstruation cups empower women and help to eradicate period taboos. Menstrual cups not only offer a sustainable menstrual hygiene solution but also support larger social and cultural changes by giving people the knowledge and ability to make conversant decisions. In this review article, few case studies are discussed which highlights the transforming potential of menstruation cups. The article serves as motivating examples for governments, non-government organizations and businesses to encourage the usage of menstrual cups in female and thereby help in developing a more inclusive and sustainable future. This study also aims towards eliminating period poverty and help in achieving the sustainable development goals (SDGs) i.e., SDG 3 (Well-being and Good Health), SDG 6 (Clean Water and Hygiene), SDG 11 (Sustainable Cities and Communities) and SDG 15 (Life on Land).
The Effect of Processing on Acorn Series Intervals on Soil Agrophysics As Well As Fiber Quality
Authors: Salomov Shavkat Turobovich  , Muhammadov Yo’ldoshbek Akmal o’g’li  , Goziev Umrzoq Lapasovich
Published: November 2023

This article provides information related to the impact of soil volume weight, porosity and seedling thickness on the quality indicators of cotton fiber on the range of Acorn care at different ranges of Acorn care in kxu-4B and milling cultivators. In this, it was noted that the agrophysic indicators of the soil improved in the range of 76 cm, compared to 60 sm (control), and the soil porosity increased by 1.4-0.3% after irrigation 1, at the end of the season, this indicator was mutonically 50.6-47.4%, 1.1-0.8% higher than the control option. When the quality indicators of the fiber were analyzed, it was found that kxu-4b between the 76 cm row and control in the complex processed variant in milling cultivators was 60 sm, copper-microneedle was 0.1, STR-specific break strength was 1.1 g strength/Tex, UI-uniformity index was 1.4, SFI-short fiber index was 0.4% less.
STRATEGI PEMASARAN IKAN LELE UD. SONIA RATU DI KABUPATEN ACEH BARAT
Authors: Aulia Muhammad Reza , Sarfida Yenda , Pranata Alif , Fadil Mirza , Larasati Larasati
Published: November 2023

Strategi pemasaran digunakan untuk mendukung kegiatan dalam meningkatkan pendapatan bisnis. Penelitian ini bertujuan untuk mengidentifikasi strategi pemasaran yang berbeda untuk UD. Sonia Ratu mengembangkan ikan lele di Kabupaten Aceh Barat serta mengidentifikasi tantangan yang dihadapi oleh strategi-strategi tersebut.  Metode Penelitian berbasis metodologi penelitian kualitatif. Pemilik, staf, dan pelanggan UD Sonia Ratu adalah informan penelitian ini. Teknik analisis data termasuk mengurangi data, menyajikan data, dan menampilkan kesimpulan.  Peneliti menyimpulkan bahwa strategi pemasaran ikan lele bisnis di UD Sonia Ratu menggunakan strategi SO (Strengths-Opportunities) yang dipilih berdasarkan analisis matriks SWOT. Tiga alternatif strategi SO telah diidentifikasi dan dieksplorasi; pertama, strategi mempertahankan kuantitas dan kualitas, kedua, strategi promosi menggunakan media digital, ketiga, strategi meningkatkan jumlah pelanggan.
Precarization of Young Indonesian Journalists During the Covid-19 Pandemic
Authors: Utomo Wisnu Prasetya
Published: November 2023

This article discusses the working conditions and vulnerabilities young journalists face in Indonesia during the Covid-19 pandemic. Drawing on in-depth interviews with ten young journalists, it explores the experiences and working conditions faced by young journalists during the pandemic. Through the lens of precarization, this article demonstrates how young journalists are exposed to multiple precarity in the media industry. They entered an industry amid a disruption phase that began before the pandemic, and the pandemic worsened the condition. The result shows that young journalists are under the shadow of precarity in performing their work.
Nigerian Agricultural Posts on Facebook and Instagram within the West African Agricultural Messaging Framework
Authors: Aliagan Isiaka Zubair , Ahmad Murtada Busair , Daranijo Habeeb Opeyemi , Na’allah Habibat Morenikeniji
Published: November 2023

This study generated and content-analyzed Facebook and Instagram postings on agricultural messages by Nigerian farmers in three years  (2019-2021) within specific contexts and in comparison with postings similar to ones initiated by private individuals and government agencies as well as those posted at continental level on the two social media channels. While the data are graphically displayed, a paired-sample T-test was conducted to establish statistically significant differences in the agricultural messages posted on the two social media by Nigerian farmers and farmers from other countries in Africa. All four null hypotheses tested were rejected as statistically significant differences were established between the paired population means. It was also found that Nigerian farmers are accustomed to the use of social media in promoting agricultural-related messages, indicating their exposure to the diffusion of agricultural innovation in line with the trends in advanced nations. It was concluded that social media remains a viable tool for promoting agriculture, particularly during food insecurity and global economic crisis. It was recommended that the Nigerian government should provide an enabling environment for agricultural promotion in the digital age.
A stockpile of neonatal antibodies pertaining to SARS Covid (COVID 19) ascertained in cord blood after complete vaccination of covishield in mother- An observational study
Authors: Krishna Abhishek S , Adithya S L  , Ahalya U  , Anil Akhila , Amal A  , Dharan Shaiju S
Published: November 2023

Maternal antibodies are a vital component of neonatal immunity. These antibodies give the baby a head start in building their immune system and fighting off diseases. The study was carried out to check the presence of IgG antibodies in cord blood of a completely vaccinated mother with Covishield and to find out if any side effects occurred during their vaccination. It was clear from the study that all the cord blood samples showed presence of antibodies and only limited side effects were observed in the vaccinated mothers.

An observational study was done in the gynecology department of a tertiary care hospital in Trivandrum from November 2022 to April 2023 (6 months duration) with 40 cord blood samples taken from completely vaccinated mothers.

A total of 40 women were included who had completed two doses of Covishield vaccine. Presence of umbilical cord blood IgG was found in all the 40 samples, i.e. Covid IgG > 17.8 BAU/mL. Among the 40 samples, 75% of them had not experienced any side effects after their vaccination while the remaining 25% had experienced minor side effects.

The findings made from this study can be used to prove that vaccines are capable of producing antibodies in mother which will be transferred to her baby through the cord blood. It is also evident that the vaccine has produced only minor side effects.
Building a More Resilient and Low-Carbon Caribbean: Report 5: Decarbonization Pathways for the Caribbean Construction Industry
Authors: Bailey Jed , Minoja Livia , Alvear Alexandra , Gischler Christiaan
Published: November 2023

The Caribbean islands are among the 25 most-vulnerable nations in terms of disasters per-capita or land area, and climate change is only expected to intensify these vulnerabilities. Within this context, the series “Building a more resilient and low-carbon Caribbean”, focuses on improving the resiliency, sustainability and decarbonization of the construction industry in the Caribbean. The first three reports of the series analyze the economic losses caused by climate related events, the benefits of improving building resiliency to reduce those economic losses and the benefits of subsidized financing for resilient buildings in the Caribbean, showing that increasing building resiliency is economically viable for the high-risk islands of the Caribbean, generating long term savings and increasing the infrastructure preparedness to the impacts of CC. The fourth report focused on the potential role for nature-based solutions (NBSs) in the region. This report extends the previous analysis to examine potential options to reduce embodied carbon in traditional resilient building materials such as cement and steel in the region.
Estudios de ecología de la atención médica: análisis comparado en dimensión histórica, 1928-2018
Authors: Spinelli Hugo , Trotta Andrés , Martinovich Viviana , Alazraqui Marcio
Published: November 2023

En la definición de las políticas de salud y en la toma de decisiones por parte de la gestión suele primar una separación entre clínica, epidemiología y salud pública, situación naturalizada desde la mirada de los hospitales y ministerios, pero artificial en los territorios, donde los problemas no se estructuran siguiendo la fragmentación de saberes, sino que se expresan en la complejidad de los problemas de las personas y los conjuntos poblacionales. Desde esa concepción, este trabajo recopila y analiza los estudios de ecología de la atención médica, realizados entre 1928 y 2018, que retoman el estudio precursor “The ecology of medical care”, de White, Williams y Greenberg, para centrar la discusión en tres ejes: 1) las regularidades presentes en los estudios de ecología de la atención médica, independientemente del año y el país; 2) los sistemas de información en salud y las encuestas de salud; y 3) la hegemonía institucional del hospital en el campo de la salud.
Historia del Proyecto de Investigación en Servicios de Salud: Entrevista a Kerr White
Authors: Berkowitz Edward D.
Published: November 2023

Se presenta la entrevista realizada en 1998 a Kerr L. White (1917-2014), traducida al español. White fue un economista, epidemiólogo, estadístico, médico general, sanitarista, muy crítico de la separación entre la investigación, la clínica, la epidemiología, la salud pública y las políticas de salud. Fue uno de los fundadores de la investigación sobre los servicios de atención médica. Su preocupación básica fue la responsabilidad de la sociedad para asignar recursos de atención médica de la manera más apropiada para mejorar la salud de las poblaciones. La producción de White señala críticamente la ausencia de una mirada poblacional en la epidemiología aplicada a servicios y sistemas de salud, y en la evaluación del impacto social y económico de las prácticas, señalando además la deshumanización de los procesos de atención y cuidado. Sus trabajos han sido poco citados en los textos del campo de la salud, por lo que recuperamos su figura con el objetivo de difundir la vigencia de su pensamiento y su obra.
MicroRNA-221-3p promotes post-burn HUVEC proliferation, migration, and angiogenesis by regulating CDKN1B
Authors: Miao Kun , Xie Fei , Lin JinGui
Published: November 2023

Background and objective: Previous studies have shown that miR-221-3p plays an important role in vascular remodeling, but it is unclear whether it contributes to angiogenesis after burn injury. The purpose of this study was to investigate the effect of miR-221-3p on angiogenesis in HUVECs after burn injury and to reveal its underlying molecular mechanism. Methods: The burn HUVECs model was established by heat treatment. Plasmid or oligonucleotide transfection altered the expression of miR-221-3p and CDKN1B in HUVECs. MTT, colony formation, Transwell, flow cytometry, and tube formation experiments were applied to assess the proliferation, migration, apoptosis, cell cycle, and tube formation capacity of HUVECs. miR-221-3p, CDKN1B, Ki-67, and PCNA expression was assessed by RT-qPCR or Western blot. The dual-luciferase reporter assay verified the targeting relationship between miR-221-3p and CDKN1B. Results: miR-221-3p was lowly expressed and CDKN1B was highly expressed in burn HUVECs. Overexpression of miR-221-3p promoted the proliferation, migration, and tube formation ability of burn HUVECs and inhibited apoptosis and the proportion of cells in the G0/G1 phase, whereas overexpression of CDKN1B had the opposite effect. Knockdown of miR-221-3p further inhibited the angiogenic capacity of burn HUVECs, but this effect was reversed by knockdown of CDKN1B. Mechanistically, miR-221-3p targeted CDKN1B. Conclusion: miR-221-3p improves the angiogenesis of burn HUVECs by targeting CDKN1B expression, and the miR-221-3p/CDKN1B axis may serve as a potential molecular target for future burn therapy.
Factors affecting the choice of treatment center by infertile couples: A cross-sectional study in Yazd Reproductive Sciences Institute
Authors: Ranjbar Mohammad , Abdoli Ali Mohammad , Shafaghat Tahereh , Jafari Hasan , Izadpanah Golnaz , Assefa Yibeltal
Published: November 2023

Background: Infertility is one of the critical health issues in Iran. There are more than 70 specialized infertility treatment centers in Iran, of which the Yazd Reproductive Sciences Institute, is one of the most important ones.
Objective: This study aimed to determine the factors influencing infertile couples’ choice of Yazd Reproductive Sciences Institute.
Materials and Methods: This cross-sectional study was conducted on 275 infertile couples aged 18 and older, referring to Yazd Reproductive Sciences Institute, Yazd, Iran from September 2021 to March 2022. Data were gathered using a 2-part questionnaire. Data analysis was done through SPSS software. We used descriptive statistics, Kruskal- Wallis, Mann-Whitney, and t test for data analysis.
Results: Most participants were individuals who came from other provinces of Iran (74.9%) and were referred to the Yazd Reproductive Sciences Institute. Among the 4 categories that influenced couples’ decision to choose this center, factors related to the personnel and treatment staff received the highest score (75.83), while personal factors received the lowest score (65.76). The average score for factors related to doctors was 72.90, and for factors related to the center, it was 73.65. The satisfaction with personnel and treatment staff varied based on participants’ education levels, with those who had lower levels of education reporting higher levels of satisfaction (p < 0.001).
Conclusion: The primary factors contributing to the success of the Yazd Reproductive Sciences Institute in attracting clients were the dedication and expertise of the staff, as well as the esteemed reputation of the doctors at the center.
Key words: Infertility, Fertility clinics, Yazd, Iran.
Jeotektonik Süreçler, Deprem Ve Maden Yatakları: Kuzey Anadolu Fay Zonu
Authors: VURAL Alaaddin , KIRAT Güllü
Published: November 2023

Yerkürenin gelişimi ve şekillenmesi maruz kaldığı jeolojik-jeotektonik olaylarla yakından ilişkilidir. Bu süreçlerle kıtaların hareketi, birleşmesi, parçalanması, yeni mikro kıtaların oluşumu yanında yitim ve dağ oluşumları gibi birçok devasa küresel olaylar meydana gelmektedir. Büyük ölçekli fay hatlarının, fay zonlarının gelişiminde, hatta günümüzde sosyal ve kültürel olayları dahi etkileyen büyük ve küçük ölçekli depremlerin oluşumunda da en önemli unsur yerkürenin maruz kaldığı jeotektonik evrim sürecidir. Tetis okyanuslarındaki Afrika, Arab ve Hindistan Plakalarının birbirine doğru yaklaşması ve akabinde de Avrasya kıtası ile çarpışması günümüzün en önemli kuşaklarından biri olan Tetis kuşağını ve ilişkili metalojeni kuşağını da oluşturmuştur. Bu kuşak Batı Akdeniz’den Çin’e kadar uzanır. Türkiye’nin en belirgin tektonik çatısı, Pontidleri, Anatolid-Torid platformundan ayıran İzmir-Ankara-Erzincan Zonu ve Arap Levhasının kuzey kenarını oluşturan Bitlis kenet zonu bu kuşak içinde yer almaktadır. Günümüz Türkiye coğrafyası, birbirleriyle karmaşık kenet zonları ile ayrılan ve Tetis okyanuslarının kalıntılarını (Paletotetis ve Neotetis okyanusları) temsil eden alt plakalara ayrılmaktadır. Türkiye’nin Jeodinamik evriminde, Pontid yayı ile Anadolu-Torid platformunun İzmir-Ankara-Erzincan Kenet Zonu boyunca çarpışmasıyla Neotetisin kuzey kolunun Geç Paleosen-Eosen aralığında kapanması önemli bir olgudur. Bu süreç aynı zamanda Türkiye’nin Neotektoniğinin ana çatısı belirlemiş olup, önemli deprem üreticisi Kuzey ve Doğu Anadolu Fay Zonlarını’n da sorumlusudur. Bu fay zonlarının gelişim süreçleri aynı zamanda bu zonlarla ilişkili önemli maden yataklarının oluşumuna da katkı vermiştir. Maden yatakları açısından değerlendirildiğinde, Kuzey Anadolu Fay Zonu’nda hidrotermal süreçler Geç Paleosen’de başlamıştır. Kuzey Anadolu Fay Zonu içinde bulunan maden yatakları dikkate alındığında, fay zonunun şekillenişi ve maden yataklarının oluşumunun ilişkisi görülebilmektedir. Biga Yarımadasındaki Kısacık altın cevherleşmesi ve Alakeçi listvenitlerindeki altın zenginleşmesi bu zondaki cevherleşmelere örneklerdir. Bu cevherleşmeler dışında da bu zonla doğrudan ve dolaylı ilişkili birçok maden yatağı söz konusudur. Dolayısıyla yerküreyi şekillendiren ana tektonik olaylar ve bunlardan kaynaklı aktif tektonik hatlar deprem gibi büyük doğal afetleri oluştururken aynı zamanda da önemli birçok doğal kaynakların da oluşumuna katkı vermektedir. İnsanların imkanları ile engellenmesi mümkün olmayan bu devasa jeolojik olayların meydana getirdiği olumlu imkanlardan yararlanırken, doğası gereği etkili olacağı doğal afetlere karşı da önlem alınarak yaşamanı sürdürmek insanoğlunun en önemli önceliklerinden biri olmalıdır.
Experimental Investigation of the Electrical Effect of Twisted Lights on a Semiconductor
Authors: KOÇ Tarık , YALÇINKAYA Fikret
Published: November 2023

Orbital Angular Momentum (OAM) beams are a special type of light that disrupts the circular symmetry of the optical field and carries the angular momentum of light. These beams enable new applications in optical devices and communication. In addition, as a result of their interaction with matter, OAM beams can transfer both photon energy and angular momentum, enabling the formation of higher currents. Thus, it has been shown that OAM beams can be used to obtain higher energies in increasing photovoltaic efficiency. The effect of OAM beams on photovoltaic efficiency has been a research topic in recent years. Some studies have theoretically shown that OAM beams can increase the electrical production of solar cells. The reason for this is that OAM beams impart angular momentum to electrons in addition to photon energy. The aim of this study is to experimentally investigate the electrical effect of an OAM beam spot produced using an SLM (Spatial Light Modulator) on a semiconductor solar panel. Higher currents were obtained by dropping the OAM beam onto photovoltaics. The current increase was 18.2%.
Infancia, diversidad y filosofía
Authors: Suárez Vaca María Teresa , Pulido Cortés Óscar
Published: November 2023

Esta publicación recrea una experiencia investigativa, un “encuentro” “sustantivo”, un llegar y hallarse con algo, una casualidad que reúne, pero que a su vez invita a otro encuentro más potente, el que se hace verbo, acción, práctica, es decir, “encontrar”, hallar algo, un descubrimiento inesperado que emociona, crea expectativas y produce afectaciones; por lo tanto se siente el nuevo llamado; pero este en particular, es el que descentra y confunde; entonces es el encuentro que choca, tropieza, incita y transforma; se convierte en provocación y pretexto para seguir proponiendo nuevos encuentros de investigación.
Learning Organization Pada Madrasah Aliyah Negeri 1 Kota Bandar Lampung
Authors: Suzana Hera , Pahrudin Agus , Patimah Siti , Junaidah Junaidah , Ayu Sovia Mas
Published: November 2023

A high level of public trust in the transformations carried out by the institution, apart from that the achievements produced by the students are quite encouraging as well as the good teaching capabilities and excellent programs. This study used a descriptive qualitative approach with data collection using interviews, observation, and documentation. In data analysis with the stages of data reduction, data display, and drawing conclusions. The results of this study indicate that: 1) System thinking at MAN 1 Bandar Lampung in the formulation of the vision is carried out jointly by involving all stakeholders to see opportunities and challenges. 2) Personal mastery can be seen from the visionary madrasa head as a professional trainer so that he is able to develop the professionalism of the people he leads through various education and training programs. 3) Mental models are built through good human relations so as to improve employee performance. 4) Shared Vision by always communicating or disseminating the vision, by communicating the values ​​contained in the vision. 5) Team Learning by always synergizing all teachers and students about what is the vision of the madrasa and trying to realize the vision.
Manajemen Konflik Pada Sekolah Tinggi Ilmu Kesehatan Bethesda Tomohon
Authors: Nelwan Julita Inggrinne , Timpal Cornelia
Published: November 2023

Implicitly conflict cannot be generalized as something that is harmful or beneficial. Conflict can improve the performance and productivity of an organization, if the leader of the organization has the ability to manage conflict. The purpose of this research is to find out how institutions manage conflicts that occur between students, students and lecturers, between fellow lecturers, lecturers and leaders. The method used in this study is a qualitative naturalistic method. The research procedures with procedures are the orientation stage, the exploration stage, and the member check stage. Data collection techniques used are observation, interviews, field notes, and documentation. Data analysis was carried out simultaneously with the data collection process. The results of the research show that the conflicts that occurred at the Bethesda Tomohon High School of Health Sciences involved: (a) student-student conflicts, (b) lecturers and lecturers or administrative staff, (c) lecturers and students, and (d) directors and lecturers.
Neuroprotective properties of GABA and its derivatives in diabetic encephalopathy in old animals
Authors: Tyurenkov I. N. , Bakulin D. A. , Smirnov A. V. , Ekova M. R. , Bisinbekova A. I. , Snigur G. L. , Velikorodnaya Yu. I. , Morkovin E. I. , Verkholyak D. V. , Vasilyeva O. S.
Published: November 2023

The aimof the workwas to evaluate the GABA neuroprotective properties and its structural analogues in old animals after seven months of hyperglycemia.

Materials and methods.Diabetes mellitus was modeled in white outbred male rats (12 months old) by the administration of a streptozotocin (65 mg/kg) and nicotinamide (230 mg/kg) combination. After 6 months, the animals with a postprandial glycemia level between 11 and 18 mmol/l were selected for the study. After the groups had been formed, the animals were administrated with GABA and GABAergic compounds (Compositions МРВАand PPC), respectively, for 1 month, the control group animals were administrated with saline. After the treatment, an oral glucose tolerance test and a set of behavioral tests aimed at studying sensory-motor (Open Field, Adhesion test, Rotarod) and cognitive functions (New Object Recognition and Morris Water Maze), as well as the functional state evaluation of the endothelium were performed. Further on, sampling of blood and brain tissues for a biochemical and enzyme immunoassay (the level of glucagon-like peptide-1 (GLP-1) and TNF-α in serum and the level of Klotho protein, BDNF, Nrf2, NF-κB and malondialdehyd (MDA) in brain homogenates), as well as a morphological analysis of changes in CA1 and CA3 neurons of the hippocampus and somatosensory cortex, was carried out.

Results.GABA and compositions with its derivatives had a pronounced neuroprotective effect in old animals with prolonged hyperglycemia. The hypoglycemic effect of the studied compositions was accompanied by an increase in the production of GLP-1. In the animals with DM, after 6 weeks of the test substances administration, higher rates of sensory-motor and cognitive functions and a less structural damage to the sensory-motor cortex and the brain hippocampus were recorded. These effects may be due to higher levels of the Klotho proteins, Nrf2 and BDNF, as well as lower levels of NF-κB, which may underlie the suppression of the oxidative stress, the reduction of MDA and inflammation (TNF-α).

Conclusion.After 6 weeks of the administration, GABA and its compositions in old animals (19 months old) significantly improved sensory-motor and cognitive functions, reduced negative structural changes in the hippocampus and somatosensory cerebral cortex.
Model for predicting risk of developing drug-induced liver injury during remdesivir therapy: observational prospective open case-control study
Authors: Shevchuk Yu. V. , Kryukov A. V. , Temirbulatov I. I. , Sychev I. V. , Mirzaev K. B. , Denisenko N. P. , Abdullaev Sh. P. , Tuchkova S. N. , Vechorko V. I. , Averkov O. V. , Sychev D. A.
Published: November 2023

Remdesivir is a drug widely used for the etiotropic treatment of COVID-19. According to a number of studies, the incidence of adverse reactions during remdesivir therapy reaches 66%, with the most common is an increase in liver function tests.

The aim of the work was to study the influence of clinical, demographic and pharmacogenetic factors on the development of drug-induced liver damage during remdesivir therapy in COVID-19 patients.

Materials and methods. The study comprised 100 hospitalized patients treated with remdesivir. The patients were divided into two groups: group 1 (n=32) – remdesivir therapy, developed an increase in the level of liver transaminases; group 2 (control, n=68) – did not develop this adverse reaction. The patients in both groups underwent a pharmacogenetic study, and a retrospective analysis of medical records was performed. Based on the data obtained, the association of clinical, laboratory, pharmacological and pharmacogenetic parameters with the development of drug-induced liver damage during remdesivir therapy was studied.

Results. In the group of patients with the development of drug-induced liver damage, people with a high body mass index were significantly more likely than in the control group (30.7±4.2 kg/m2 in group 1 vs. 27.3±5.5 kg/m2 in group 2, p=0.003), with a history of diabetes mellitus (odds ratio (OR)=2.647, 95% confidence interval (CI)=1.092–6.414, χ2=4.785, p=0.029), with higher levels of ferritin in the blood (724.03±432.27 and 553.19±358.48 mg/mol, respectively, p=0.040), receiving therapy with angiotensin-converting enzyme inhibitors (OR=5.440, 95% CI=2.160–13.699, χ2=14.027, p=0.000), statins (OR=3.148, 95% CI=1.307–7.581, χ2=6.795, p=0.009), and also being heterozygous for the polymorphic marker rs776746 of the CYP3A5 gene (OR=3.961, 95% CI=1.343–11.686, χ2=6.772, p=0.009).

Conclusion. A high body mass index, a history of diabetes mellitus, high levels of ferritin in the blood, concomitant therapy with angiotensin-converting enzyme inhibitors and statins, as well as a carriage of the AG genotype for the polymorphic marker rs776746 of the CYP3A5 gene increase the likelihood of developing drug-induced liver damage during remdesivir therapy. In this regard, it is necessary to consider these factors when prescribing remdesivir therapy, conduct a more careful monitoring of clinical and laboratory indicators of liver damage, and develop personalized approaches to the treatment of COVID-19 patients.
Unravelling the Cinematic Tapestry of Immigration: A Socio-Cultural Disccection of Indonesian Migrant Labor in Rawuh (2019)
Authors: Sukmawati Ni Luh Ayu
Published: November 2023

This article addresses the representation of Indonesian migrant labor experiences, particularly from Jember, in local cinema by presenting a multifaceted analysis of the film Rawuh (2019). The study emphasizes the film's depiction of socio-cultural dynamics and its contribution to existing discourses on immigration and migrant labor. Utilizing close textual analysis and scrutinizing mise-en-scène elements such as setting, lighting, costume, and props, the paper probes the film's representation of the rural community's aspirations for upward social mobility, as well as the repercussions of immigration on the characters' lives and societal dynamics. Moreover, by integrating theories by Pierre Bourdieu and pertinent literature on social class, cultural capital, and habitus, the study delves into the film's portrayal of social class and inequality, illuminating the intricate interplay between cultural assets, social stratification, and the quest for distinction. Through a rigorous examination of the film, the study underscores the ways in which Rawuh (2019) intersects with and contributes to ongoing discourses on immigration, labor, and global economic forces, accentuating the film's pertinence to contemporary debates surrounding the experiences and challenges encountered by Indonesian migrant workers from Jember. Based on the analysis also serves as evidence that local films have the potential to offer a more authentic portrayal of their respective societies, as they tend to closely engage with the prevalent issues in their immediate surroundings.
VISUALISASI MASKULINITAS TOKOH SANCAKA PADA FILM GUNDALA (2019)
Authors: Pranela Firda Miaz , Aji Fajar , Hartanto Denny Antyo
Published: November 2023

Film Gundala (2019) merupakan salah satu film yang mengangkat kisah superhero Indonesia karya Joko Anwar. Penelitian ini bertujuan untuk mendeskripsikan maskulinitas tokoh Sancaka melalui aspek mise en scene pada film Gundala (2019). Penelitian ini menggunakan teori mise en scene sebagai teori utama dan teori maskulinitas Janet Saltzman Chafetz sebagai teori pendukung. Jenis penelitian yang digunakan adalah metode penelitian deskriptif dengan pendekatan kualitatif. Objek penelitiannya yakni film Gundala (2019), sedangkan subjek penelitiannya berupa mise en scene film Gundala (2019) dan kajian maskulinitas tokoh Sancaka dalam film Gundala (2019). Hasil dari penelitian ini dapat disimpulkan bahwa mise en scene dapat menvisualisasikan maskulinitas tokoh Sancaka pada film Gundala (2019).
ELASTISITAS SYARIâ€™AT ISLAM DALAM PERUBAHAN SOSIAL
Authors: Syaripuddin Said
Published: November 2023

Penelitian ini bertujuan untuk menguji fleksibilitas hukum Islam di tengah-tengah perubahan sosial, berupaya untuk menggambarkan sifat komprehensif dan karakter teks hukum Islam dan menganalisis faktorfaktor syariah yang memiliki relevansi untuk perubahan sosial. Tulisan ini merupakan penelitian deskriptif kualitatif dengan menggunakan pendekatan multidisiplin termasuk pendekatan yuridis normatif, asas manfaat, dan pendekatan sosiologis. Studi ini menunjukkan bahwa isi teks syariah inklusif sehingga memungkinkan untuk ditafsirkankembali. Ada beberapa faktor yang menyebabkan Syariah menjadi dinamis dan relevan untuk beradaptasi dalam lingkungan baru. Pertama, ada sejumlah isu syariah yang tidak dijelaskan pada status hukumnya. Kedua, pada umumnya teks syari'ah menjelaskan semuamasalah. Ketiga, teks-teks syariah umumnya memiliki banyak "multitafsir". Keempat, hukum Islam mengakui kondisi darurat dan force majeure (istisnaâ€™) sebagai pengecualian hukum. Kelima, hukum Islam bersifat elastis, materi dapat diubah tergantung pada waktu, tempat, dan situasi. Oleh karena itu, pemahaman teks syari'ah harus terus dipertahankan dengan memperhatikan lingkungan di mana mujitahid hidup. Jadi mujtahid dapat menguraikan berbagai penafsiran teks syariâ€™ah sebagai akibat dari pengaruh yang mereka terima baik dari aspek waktu maupun lingkungan.