bluuebunny/crossref_metadata_2025 huggingface dataset:
Characteristics of Mudflow Distribution and Evolution of Mudflow Fan in Erlian Village
Authors: Wu Xinning , Yan Huijun , Wei Sailajia , Wei Zhengfa , Wu Kai , Zhou Zhaohua , Wang Ming
Published: November 2024

Debris flow in the upper Yellow River is very developed and is generally characterized by wide distribution with large numbers and a high frequency of occurrence. This paper analyses the distribution characteristics, material composition, and formation causes of the Erlian debris flow fan in the eastern part of the Guide Basin and discusses the relationship between debris flow fan and river evolution. Results show that: (1) At least 66 debris flow gullies and 20 large debris flow accumulation fans have been developed on both sides of the Yellow River in the eastern Guide Basin. (2) In the Erlian Village area, the Yellow River channel has experienced the accumulation, erosion, destruction, and accumulation process of debris flow fans in 16 kaB.P., 16 ka B.P.–8 ka B.P., and 8 kaB.P., respectively, the late-accumulation fan has been continuously extruding the Yellow River channel since 8 kaB.P., and the Yellow River channel has been shifted to the south by at least 1.25 km during the period of 8 ka. (3) Five accumulation periods for the Late Mudslide Fan were identified by classifying the 16 kaB.P. and 8 kaB.P. early and late mudslide fans. This study can provide theoretical and technical support for preventing debris flow disasters in the upper reaches of the Yellow River and has certain reference and reference values.
Consumer Acceptance, Social Behavior, Driving, and Safety Issues Regarding Electric Vehicles in Oman
Authors: Jayabalan Sabareesaan Kannammal , Albusaidi Ahmed Said Obaid , Negi Gaurav Singh , Iqbal Mohammed Ismail , Abdulqader Hussein Al
Published: November 2024

Following Vision 2040, Oman seeks to achieve economic diversification and environmental sustainability. In this context, the world’s quest of going electric brings along opportunities as well as challenges. This study aims at determining the key barriers and facilitators of EV adoption in the country. This study examines factors such as consumer acceptance, engagement, and safe driving in relation to EVs, with a specific focus on Oman. To establish what Omani clients prefer, what worries them most, and whether they would consider making the switch to electric vehicles, empirical data on a sufficiently representative number of Omani clients were collected through a survey. According to the responses, 55% of the participants reported that they would be willing to think about purchasing an electric vehicle (EV) for their next car, which suggests a somewhat moderate level of consumer acceptance. Adoption is hindered primarily by concerns about the reliability of batteries in extreme weather conditions, high purchase prices, fear of running out of charge, and lack of sufficient charging stations. Most of the EV drivers appreciate the calm and ease of driving an electric vehicle. As the report states, certain actions must be taken, including creating public awareness through educational programs and campaigns, providing government subsidies or financial incentives, and creating the necessary infrastructure for charging equipment. To address these issues and quicken the pace of Oman’s transition to electric vehicles, this calls for collaboration among policymakers, car manufacturers, and transport planners. Aside from offering actionable recommendations regarding eco-friendly means of transport in Oman, which is relevant to the acceptance of electric vehicles in the country, this research also enhances the understanding of the issues related to the acceptance of electric vehicles in the country.
Una experiencia asociativa para la innovación en la industria de chacinados de Chaco (Argentina)
Authors: Camprubí Germán Edgardo , Prpich Noelia Zuema Palavecino , Jaimes Diego Esteban , Galante Nadia Soledad , Cayré María Elisa , Castro Marcela Paola
Published: November 2024

El grupo de investigación del Laboratorio de Microbiología de Alimentos del INIPTA (CONICET-UNCAUS) ha diseñado un prototipo de embutido fermentado funcional (EFF) que incluye el uso de un cultivo iniciador y una mejora del perfil nutricional (reducción de cloruro de sodio y grasa), logrando mantener sus características sensoriales típicas a escala laboratorio. Este desarrollo tecnológico podría tener un alto impacto en la industria de chacinados de Chaco (Argentina) ya que permitiría una innovación de producto con proyección nacional.  El objetivo del presente trabajo fue relevar y analizar el mercado territorial para introducir este nuevo EFF. Para ello se diseñó una encuesta cuali-cuantitativa semiestructurada con bloques temáticos, que se utilizó en entrevistas a chacineras con actividad comercial en la provincia. Los resultados permitieron caracterizar las chacineras según sus aspectos generales, productivos y técnicos, además de exponer el interés en innovación tecnológica. Los establecimientos entrevistados: a) elaboran embutidos fermentados además de otros productos; b) venden en locales propios, supermercados y otros mercados provinciales; c) tres de las chacineras poseen integración con la industria de primera transformación; d) las líneas de producción presentan equipos artesanales o semiautomáticos. El 100% de las firmas implementan BPM, el 60% POES y el 80% consideró conveniente la incorporación de tecnología, y  modificaciones en la formulación de sus productos. Se estima que el EFF tendría aceptación a un precio diferenciado, indicando que se podría trabajar en forma asociativa con estas industrias para encarar actividades de upgrading de proceso y producto para promover una innovación en el mercado regional.
СЕМАНТИКО-ФУНКЦІЙНЕ НАВАНТАЖЕННЯ ФРАЗЕОЛОГІЧНИХ ОДИНИЦЬ У РІЗНОЖАНРОВИХ ТВОРАХ В. ВИННИЧЕНКА
Authors: Заброцька Д. Р. , Лебеденко Ю. М.
Published: November 2024

Стаття присвячена дослідженню фразеологічного фонду творів В. Винниченка. Письменник часто поєднує кілька фразеологізмів у близькому контексті, відображаючи стан персонажа якомога повніше. Автор вводить
варіанти фразеологізмів, трансформує їх: змінює граматичну форму, роз-
ширює або усікає компонентний склад, замінює компоненти, актуалізує по-
двійний зміст чи просто використовує фразеологічний натяк або вдається
до розгорнутої метафори. Фразеологічні одиниці відповідно до контексту,
ідейного задуму часто піддаються індивідуально-авторській обробці й онов-
люють фразеологічний образ.
ФРАЗЕОЛОГІЗМИ З КОМПОНЕНТОМ СЕРЦЕ (НА МАТЕРІАЛІ УКРАЇНСЬКОЇ ХУДОЖНЬОЇ ЛІТЕРАТУРИ 1991–2013 ТА 2014–2023 РОКІВ)
Authors: Лотоцька Н. Я. , Шептицька І. В.
Published: November 2024

Статтю присвячено вивченню структурних особливостей фразеологіз-
мів з компонентом СЕРЦЕ із застосуванням корпуснобазованого та статис-
тичного підходів в українських художніх текстах 1991–2013 та 2014–2023
років на базі корпусного інструмента ГРАК. У процесі дослідження виявле-
но, що ФО з компонентом СЕРЦЕ є досить поширеними в українській прозі,
тимчасом як найпродуктивнішими структурними моделями є словосполу-
чення дієслово + іменник і просте непоширене двоскладне речення, а найпоширеніші фразеологізми простежено в підкорпусах обох періодів.
ІНСТРУКЦІЯ ДО ТЛУМАЧНОГО СЛОВНИКА УКРАЇНСЬКИХ БДЖІЛЬНИЦЬКИХ ТЕРМІНІВ
Authors: Кубич І. В.
Published: November 2024

У статті подано концепцію майбутнього словника; розроблено інструк-
цію до тлумачного словника українських бджільницьких термінів. З’ясовано
поняття «термінологічний словник», «дефініція»; умовно подано структуру
словника бджільницьких термінів та основні принципи його укладання. На-
ведено приклади тлумачення термінів бджільництва. Вихідним результа-
том стане словник
ОБРАЗ РОСІЙСЬКО-УКРАЇНСЬКОЇ ВІЙНИ: МОДЕЛІ ВЕРБАЛІЗАЦІЇ ГЕРОЇКИ УКРАЇНЦІВ
Authors: Космеда Т. А.
Published: November 2024

Наукова студія виконана в аспекті теорії лінгвоаксіології із залученням
функційно-прагматичної наукової парадигми. Презентовано мовний образ війни у фокусі моделювання її героїки, що зреалізовано на основі актуалізації системи лексико-семантичних неологізмів. Виокремлено кілька моделей: образ героїчного українського народу, конкретні реальні та ір-
реальні образи агенсів, міфологізовані номінації, назви, що утворені на оригінальних асоціаціях; героїзується також світ фауни і флори, реальні предмети довкілля, топонімні назви, що набули статусу символів. Виокремлено характерні образні засоби, що залучені для творення зазначених образів.
КОГНІТИВНО-КОМУНІКАТИВНИЙ АСПЕКТ ВІДТВОРЕННЯ НАЗВ КВАЗІРЕАЛІЙ В АНГЛО-УКРАЇНСЬКИХ ПЕРЕКЛАДАХ ФЕНТЕЗІ
Authors: Мартинюк А. П. , Северін М. О.
Published: November 2024

У статті викладено результати когнітивно-комунікативного аналізу
англо-українського перекладу назв квазіреалій з роману Джоан Роулінг «Гаррі Поттер і напівкровний принц». Побудовано когнітивні моделі, які стоять вихідними і перекладеними мовними виразами і санкціонують їх функціювання. кореляції між компонентами когнітивних моделей, які ак-
тивуються вихідними і перекладеними мовними виразами і спрогнозовано
комунікативну вдалість / невдалість перекладу. Доведено, що когнітивне
моделювання забезпечує чіткість процедури, а комунікативний аспект ана-
лізу дозволяє об’єктивно підійти до оцінки якості перекладу
ВПЛИВ КУЛЬТУРНИХ СТЕРЕОТИПІВ НА ФУНКЦІОНУВАННЯ ВЕРБАЛЬНИХ ТА НЕВЕРБАЛЬНИХ КОМПОНЕНТІВ КОМУНІКАЦІЇ У МІЖКУЛЬТУРНОМУ РОДИННОМУ ДИСКУРСІ
Authors: Солощук Л. В. , Трач Х. В.
Published: November 2024

Стаття присвячена дослідженню впливу культурних стереотипів на
функціонування вербальних та невербальних компонентів комунікації у міжкультурному родинному дискурсі, зокрема в міжнаціональних парах, один ізякої є носієм американської лінгвокультури, а інший − представником лінгвокультури, який у відносинах спілкується англій-
мовою. Аналіз стереотипізації в міжкультурному родинному
є важливим напрямом сучасної лінгвістики та соціології, оскільки стереотипи відіграють ключову роль у формуванні міжкультурних відносин у процесі комунікації. У міжкультурному контексті стереотипи, як когнітивні конструкції, дозволяють нам спрощувати складні соціальні реалії, але водночас вони можуть призводити до неправомірних узагальнень і упереджень. З метою налагодження конструктивно спрямованого спілкування комуніканти використовують стратегію подолання стереотипів, яка реалізується певними тактиками залежно від типу стереотипу і є спрямованою на мінімізацію впливу стереотипів для забезпечення гармонійності процесу комунікації
ОЙКОНІМ ХАРКІВ У ЩОДЕННИКОВОМУ ДИСКУРСІ ОЛЕСЯ ГОНЧАРА: НОМІНАТИВНО-АКСІОЛОГІЙНИЙ ПОТЕНЦІАЛ
Authors: Степаненко Н. С.
Published: November 2024

У статті висвітлено специфіку функціювання прецедентного ойконі-
ма Харків і прямих та опосередкованих утворень від нього – хороніма Харківщина, катойконіма харків’янин (харків’янка, харків’яни), атрибутива харківський – у щоденниковому дискурсі О. Гончара. За допомогою прийомів статистичного методу встановлено ступінь уживаності досліджуваних онімно-апелятивних одиниць. Вирізнено й системно проінтерпретовано регулярну для них номінативно-локалізаційну, або реально-номінативну, функцію з її типовими локативно-аксіологійними координатами «місце дії», «напрям руху», «шлях руху», а також субфункції, зокрема темпоральну, констатувальну й оцінну. Комплексно схарактеризовано щоденникову подієвість, інваріантним експлікатором якої є пропріатив Харків, у проєкції
на ойконімно-антропонімні сюжети, вирізнені на основі контекстуально-
ідентифікувальних сем ‘[авто]біографізм’, ‘особистості’, ‘мовна ситуація
в Україні’. Аналіз функційного потенціалу, змістового наповнення, символьного коду прецедентного оніма Харків як однієї зі знакових констант прецедентного діарійного тексту здійснено крізь призму авторської екзистенції та принципу дії соціальних чинників. Така дослідницька технологія логізує, аргументує, зрештою, концептуалізує засадничі положення пропонованої наукової розвідки.
ЛІНГВОПОЕТИЧНІ СТУДІЇ ХХ–ХХІ СТОЛІТТЯ КРІЗЬ ПРИЗМУ ІДЕЙ ОЛЕКСАНДРА ПОТЕБНІ Й ДМИТРА ОВСЯНИКО-КУЛИКОВСЬКОГО
Authors: Скоробогатова О. О. , Козлова А. Г.
Published: November 2024

Стаття описує зв’язок сучасних лінгвопоетичних теорій з базовими
ідеями представників Харківської філологічної школи (ХФШ) Олександра
Потебні і Дмитра Овсянико-Куликовського. Стверджується, що розвиток
стилістики, поетики й лінгвопоетики впродовж ХХ століття відбувався
в напрямі поєднання лінгвістичних, літературознавчих й етнографічних
векторів дослідження, які були започатковані представниками ХФШ. Цей
підхід дав поштовх розвитку як мовознавчих, так і літературознавчих
та етнографічних теорій. Увага приділяється зв’язку психологічного характеру мовотворчості з теорією сигналізації Юрія Кнорозова, зокрема дослідженню фасцинативності поетичного тексту, яке, на нашу думку, пов’язане з ідеями ХФШ.
Impact of the Diagnosis-Intervention Packet Payment Reform on Provider Behavior in China: A Controlled Interrupted Time Series Study
Authors: Wang Ruixin , Yan Jiaqi , Zhang Xinyu , Qian Mengcen , Ying Xiaohua
Published: November 2024

Background: China has developed a novel case-based payment method called the DiagnosisIntervention Packet (DIP) to regulate healthcare providers' behavior. G city, a metropolis in southeast China, has shifted its payment policy from fixed rate per admission to DIP under regional global budget since 2018. This study examined the immediate and trend changes in provider behavior after this payment reform. Methods: Discharge data in G city between 2016 and 2019 was used, covering more than 10 million inpatient cases in 320 hospitals. A counterfactual scenario was developed to assign insured and uninsured inpatients across the study period to specific DIP groups under consistent rules. Controlled interrupted time-series (ITS) analyses were performed, with uninsured inpatients as control. Outcomes included inpatient volume, average DIP weight (similar to case-mix index in Diagnosis-Related Groups), and two innovative indicators (average diagnostic weight and average treatment weight) to decompose the changes in DIP weight. Subgroup analyses were conducted for different hospital levels and 21 major disease categories. Results: After the DIP reform, monthly trend of inpatient volume decreased (-1085.34, P=0.052), while monthly growth of average DIP weight increased (2.17, P=0.02). No significant changes in average diagnostic weight were observed. Monthly trend of average treatment weight increased (2.38, P=0.001) after the reform. Secondary and tertiary hospitals experienced insignificantly decreased inpatient volume and elevated average DIP weight, accompanied by negligible change in average diagnostic weight and significant increase in average treatment weight. Primary hospitals experienced reduced inpatient volume and stable average DIP weight, along with increase in average diagnostic weight and decrease in average treatment weight. Conclusion: By differentiated payments for severity, DIP induced hospitals to shift their focus from volume to weight of inpatients. Instead of diagnostic upcoding, hospitals responded to the DIP reform primarily by increasing treatment intensity. Primary hospitals may face financial risks under regional competition.
Training it Forward: The Role of Embedded Research Fellows in the Network of Scholars Program in Nova Scotia Comment on "Early Career Outcomes of Embedded Research Fellows: An Analysis of the Health System Impact Fellowship Program"
Authors: Murphy Gail Tomblin , Sampalli Tara , Embrett Mark , Lawrence Logan , Sim Meaghan , Guk Julia , Murphy-Boyle Kaylee , MacInnis Marta
Published: November 2024

Kasaai et al describe the career trajectories of embedded scientists trained through the Health System Impact Fellowship (HSIF), showing that 37% of 2017–2019 HSIF alumni continue as embedded researchers in health systems. These findings suggest that the HSIF program effectively supports career readiness in health services and policy research (HSPR). Similarly, the Network of Scholars (NoS) program, launched post-pandemic in Nova Scotia, mirrors these results, with alumni continuing in embedded roles and mentoring a new cohort of learners from undergraduate to postgraduate levels. NoS has incorporated competencies in quality, project management, and innovation to strengthen training for embedded scientists, aligning with the mandate of the Institute of Health Services Policy and Research. Since 2021, NoS has supported over 100 learners, contributing to over 300 rapid reviews and 100 rapid evaluations addressing top health system priorities while enhancing learner competencies and advancing Nova Scotia’s Learning Health System (LHS) vision.
A neuropsychiatric systemic lupus erythematosus presenting with acute confusional state: a case report
Authors: Ebrahimi Aliasghar , Ebrahimi Chaharom Faegheh , Vakilipour Pouya , Tahsini Tekantapeh Sepideh
Published: November 2024

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease characterized by variable clinical symptoms. It disproportionately affects African-American women and women from other ethnic groups. The complexity of SLE, stemming from its genetic and phenotypic diversity, poses challenges in diagnosis, treatment, and development of novel therapies. Neuropsychiatric systemic lupus erythematosus (NPSLE) encompasses a spectrum of neurological syndromes involving the central, peripheral, and autonomic nervous systems, as well as psychiatric syndromes diagnosed in SLE patients after ruling out other causes. Neuropsychiatric manifestations typically emerge in the later stages of SLE (10–75%). The acute onset of neuropsychiatric symptoms as the primary presentation of NPSLE is exceptionally rare and can be diagnostically elusive when other organs are unaffected. In this article, we present the case of a 53-year-old woman who was admitted to the hospital due to disorientation and an acute confusional state. Following the diagnosis of NPSLE, she received treatment consisting of three doses of pulse corticosteroids and one dose of cyclophosphamide. She exhibited a favorable clinical response, leading to partial resolution of her symptoms and subsequent discharge from the hospital. Practical Implications. Due to the rarity and diverse clinical presentations of NPSLE, particularly with the sudden onset of neuropsychiatric symptoms, there is a significant risk of delayed or incorrect diagnosis, which can lead to ineffective treatment. Therefore, maintaining a high index of clinical suspicion is paramount for achieving early and accurate diagnosis, which is crucial for initiating timely and effective treatment strategies.
Comparison of hot and cold executive functions of patients with Bipolar disorder type I with non-suffering individuals
Authors: Tayebi Batoul , Ghoreishi Abolfazl , Ahmadi Gholamreza , Nejad ebrahim Soumee Zahra , Mardani Parnaz , Mousavi Seyedeh Elnaz
Published: November 2024

Background. The present study was conducted with the aim of comparing the hot and cold executive functions of patients with bipolar disorder (BD, I) and non-suffering individuals. Methods. In the current cross-sectional-analytical research, 140 individuals were selected as the sample size. The participants were chosen based on diagnostic interviews using SCID-I and SCID-II and placed in two groups. The collected data were analyzed by the analysis of variance for two groups (two-sample Hotelling’s T2). Results. The results showed that the reappraisal scores in the patient group were significantly lower than in the control group (P<0.001). In the two groups, there was a significant difference in inhibitory control as well as in its other subscales, namely, commission (P<0.001), omission error (P<0.001), inhibition (P<0.001), and response time (P<0.001). Regarding the cognitive flexibility variable and its subscales, the two groups were significantly different, except for failure to maintain the sequence (P=0.21) in the number of categories (P<0.001), perseverative errors (P<0.001), correct answers (P<0.001), and incorrect answers (P<0.001). Conclusion. Based on the findings, patients with BD had significant deficits in terms of emotion regulation strategies, inhibitory control, and cognitive flexibility compared to non-sufferers that can be considered in pre-clinical and clinical studies of BD. Practical Implications. Due to the significant difference between the variables of emotion regulation, inhibitory control, and cognitive flexibility between the two groups, it is possible to use the present findings in the direction of necessary therapeutic interventions for these patients and to increase the effectiveness of the treatment while reducing the functional deficits of these patients.
Investigation of the diagnostic value of neutrophil-to-lymphocyte ratio for evaluating the severity of pancreatitis in patients with acute pancreatitis
Authors: Alizadeh Leila , Alishvandi Ali , Moslemifar Hamideh , Sadrazar Amin , Afshan Mohsen , Nouri-vaskeh Masoud , Hamzehzadeh Sina
Published: November 2024

Background. Acute pancreatitis (AP) is considered a gastrointestinal disorder that may lead to a systemic inflammatory response and requires urgent hospitalization. Currently, the bedside index of severity in acute pancreatitis (BISAP) scoring system is used to estimate the severity of the disease. This study sought to investigate the significant relationship between the infectious inflammatory components of the neutrophil-to-lymphocyte ratio (NLR), which can only be obtained by a simple blood test. Then, this ratio was compared with the BISAP scoring system. Methods. This cohort study was conducted at Imam Reza Hospital of Tabriz University of Medical Sciences in 2017‒2018. A total of 98 hospitalized patients with our desired criteria were included in the study. A complete blood count differential was obtained, and the BISAP score was calculated and analyzed, along with demographic data. Results. The NLR and the age of patients had a significant relationship with the BISAP variable (P < 0.05). For one unit (year) increase in patients’ age, the chance of being placed in the higher categories of the BISAP score increased by 1.14 and 1.09 times, respectively. Gender, smoking, and underlying diseases had no significant relationship with the BISAP score (P > 0.05). Conclusion. The initial values of the NLR can be used to determine the prognosis and severity of the disease in patients with acute pancreatitis in a quick, easy, and accessible way. Practical Implications. Simple ratios such as NLR can be utilized to perform immediate measurements for the management of acute pancreatitis.
Comparison of the oral health indices in patients with type II diabetes with different glycemic control levels: a case-control study
Authors: Hashemi Mohsen , Hassanpour Shirin , Sadra Vahideh , Aghazadeh Zahra , Amini Dehkordi Arman , Katebi Katayoun
Published: November 2024

Background. Glycemic control and oral health have a two-way relationship. The objective of this study was to compare dental caries and gingival indices in type II diabetic patients based on hemoglobin A1c (HbA1c) levels. Methods. In this case-control study, 150 type II diabetic patients were studied in three groups with HbA1c below 7%, between 7‒9%, and above 9%. The decayed, missing, and filled teeth (DMFT) index and gingival index were determined by oral examination. Demographic variables were collected through patient files. A blood test was requested to measure HbA1c. The data were analyzed using SPSS 17, and the significance level was set at P<0.05. Results. There was a statistically significant difference in the mean number of decayed teeth (P=0.017), missing teeth (P=0.034), and overall DMFT index between the three groups (P<0.001). The mean number of filled teeth between the three groups was not significant (P=0.346). The mean gingival index in the group with HbA1c above 9% was significantly higher than the other two groups (P=0.015). Conclusion. The gingival index and DMFT increased with an increase in HbA1c. In other words, diabetes had more negative effects on gingival and dental health when its control was poorer. Practical Implications. Considering that the level of diabetes control has a great impact on oral health, it is necessary for diabetic patients, especially patients whose HbA1c is higher than 7%, to be regularly examined for teeth and gingival problems.
Doğal Gaz Fiyatının Elman Sinir Ağları ve Yusufçuk Optimizasyon Algoritmasına Dayalı Hibrit Model ile Tahmini
Authors: Karasu Seçkin
Published: November 2024

Dünya nüfusunun artışı ile çeşitli fosil ve yenilenebilir enerji kaynaklarının kullanımı giderek artmaktadır. Doğal gaz, fosil enerji kaynakları arasında yer alan kömür ve petrolle karşılaştırıldığında, daha düşük karbondioksit emisyonu, yüksek verimlilik, kolay erişim ve düşük depolama maliyeti gibi özellikleri nedeniyle bireysel ve kurumsal düzeyde kullanım alanı bulmuştur. Doğal gaz fiyatı ekonomik açıdan önemli olduğu kadar stratejik öneme de sahiptir. Özellikle doğal gaz fiyatının gelecekte alacağı değerin tahmini, enerji üreticilerine ve tüketicilerine, yatırımcılara ve hükümetlere stratejik kararlar alırken yol gösterici olmaktadır. Bu çalışmada, Elman Sinir Ağları (ENN) ve Yusufçuk Optimizasyon Algoritması (DOA) yaklaşımları kullanılarak bir adım sonraki doğal gaz kapanış fiyatının tahmini yapılmıştır. Çalışma 01,06,2009-31,05,2024 tarihleri arasında 3986 adet kapanış fiyatı içeren veri seti kullanılarak yapılmıştır. Bir adım sonraki kapanış fiyatının tahmini için yapay zekâ yaklaşımlarından ENN yöntemi kullanılmıştır. Geri beslemeli sinir ağları arasında yer alan ENN, geçmiş verileri dikkate alarak gelecekteki değerleri tahmin etme yeteneğine sahiptir ve özellikle zaman serisi tahmininde kullanılmaktadır. Model eğitim aşamasında yusufçukların avlanma ve göç etme davranışlarından ilham alınarak geliştirilmiş bir sezgisel optimizasyon algoritması olan DOA yöntemiyle ENN’nin ağırlık ve bias değerleri bulunmuştur. Modelin değerlendirilme aşamasında veri setinin eğitim, doğrulama ve test setlerine bölünmesiyle modelin genelleme kapasitesi daha güvenilir bir şekilde ölçülmektedir. Model başarımı, çeşitli istatistiksel hata kriterleri kullanılarak değerlendirilmiş ve elde edilen sonuçlar tatminkâr bulunmuştur. Yapay zekâ yaklaşımlarının kullanımı, enerji piyasaları gibi dinamik ve karmaşık sistemlerde tahmin doğruluğunu artırmak için kritik önem taşımaktadır. ENN ve DOA’nın birleşimi, bu tür problemler için güçlü ve esnek bir çözüm sunmaktadır. Bu çalışma, doğal gaz fiyatlarının tahmininde yapay zekâ yöntemlerinin etkinliğini göstermekte ve bu yaklaşımların pratik uygulamalarda kullanılabilirliğini ortaya koymaktadır.
Oral Cancer Classification with CNN Based State-of-the-art Transfer Learning Methods
Authors: Gümele Kaan , Başarslan Muhammet Sinan
Published: November 2024

The importance of oral and dental health closely affects other vital organs. In this study, CNN-based transfer learning models are built on histopathologic and intraoral images with benign and malignant lesions. Histopathologic and intraoral images from two different sources have benign or malignant classes of lesions in the mouth. EfficientNetB7, ResNet50, VGG16, and VGG19, Xception, ConvNextBase, and MobileNetV2 were used as transfer learning methods. Model training was performed with 80%-20% train test separation and 20% validation separation on the train set. Accuracy (Acc), Precision (Prec), Recall (Rec), and F1-score (F1) metrics were used to evaluate the model. In histopathologocial images, ResNet50 was ahead with 0.8125 Acc and 0.8525 F1. In intraoral images, ConvNextBase with 0.84 Acc, and 0.80 F1 was found to be more accurate.
Cultural Echoes: Navigating the Legacy and Evolution of Bangla Musical Instruments or, Resonance through Time: A Journey into the History and Future of Bangla Musical Instruments
Authors: Hossain Mridha Md. Anwar , Tasneem Jakia
Published: November 2024

This research investigates the importance of musical instruments, emphasizing their role in expressing and preserving cultural identity. It highlights their significance in conveying emotions, playing ceremonial and ritualistic roles, fostering social cohesion, preserving traditions, contributing to global music fusion, impacting tourism, and holding symbolism and spirituality. The study then focuses on Bangladesh's rich history of musical instruments, exploring the diverse heritage and cultural expressions, aiming for a robust and credible exploration of the history and future of Bangla musical instruments. The researcher interviewed critical stakeholders, including artists, musicologists, lyricists, tuners, instrumentalists, and media personnel. A comprehensive literature review and the researcher's insider perspective from a government-owned radio organization provided additional insights. Structured and semi-structured interviews were used for primary data collection, employing qualitative analysis techniques.
Физико-химические и фармаколого-токсикологические свойства адсорбентов, полученных из цеолитсодержащих горных пород
Authors: Б.И. Шапиев , А.А. Алиев , М.М. Магомедов , К.Б. Шапиева
Published: November 2024

Цель исследования: определение химического состава, физических и адсорбционных свойств образцов природных цеолитов Левашинского месторождения. Материал и методы. Для изучения токсикологических свойств исследуемых образцов, проведены опыты на белых мышах. Результаты качественного и количественного исследования фазового состава цеолитсодержащих горных пород показывают, что более 98 от общей массы исследованного без предварительной физической и химической обработки образца цеолита составляют следующие фазы: SiO2, Al2O3, CaO, MgO, Na2O, K2O, Fe2O3. Все перечисленные фазы в мелкодисперсном состоянии имеют большую суммарную поверхность и обладают ярко выраженными адсорбционными свойствами, высокой кинетикой и большой адсорбционной емкостью. Практически все перечисленные фазы применяются в различных отраслях народного хозяйства для адсорбционного разделения веществ, очистки различных сред от примесей и токсикантов, в том числе в медицине и ветеринарии. Заключение. При однократном введении в желудок белым мышам различных массовых доз цеолита не наблюдалось видимых изменений в общем состоянии и поведении мышей как в дни непосредственного введения, так и в последующие дни. Визуально не обнаружено признаков острого отравления. Из-за низкой токсичности исследуемых образцов цеолитов не определены их среднесмертельные дозы (LD50).

Objective: Physicochemical studies of natural zeolites of the Levashinskoye deposit were carried out in order to determine their chemical composition, physical and adsorption properties Material and methods. To study the toxicological properties, experiments were carried out on white mice. Results. of the qualitative and quantitative phase composition of celite-containing rocks show that more than 98 of the total mass studied without preliminary physical and chemical treatment of a zeolite sample consists of the following phases: SiO2, Al2O3, CaO, MgO, Na2O, K2O, Fe2O3. All of these phases in a finely dispersed state have a large total surface and have pronounced adsorption properties, high kinetics, and large adsorption capacity. Almost all of these phases are used in various sectors of the national economy for adsorption separation of substances, purification of various media from impurities and toxicants, including in medicine and veterinary medicine. Conclusion. With a single introduction into the stomach of white mice of various mass doses of zeolite, no visible changes were observed in the general condition and behavior of the mice, both on the days of direct administration and on the following days. Visually, there were no signs of acute poisoning. Due to the low toxicity of the studied zeolite samples, the average lethal doses (LD50) have not been determined.
Заболеваемость аллергическим ринитом населения экологических зон Дагестана
Authors: А.Р. Алиева , Ю.А. Джамалудинов , Ю.М. Атаева
Published: November 2024

С целью оценки заболеваемости аллергическим ринитом (АР) мужского и женского населения Дагестана провели сравнительный анализ в зависимости от экологических зон Республики Дагестан (РД). Материал и методы. Все зарегистрированные случаи (33 721 больной) АР в Республике Дагестан за 2014-2018 годы были распределены по полу и месту жительства пациентов (город, приморье, неприморье, село, равнина, предгорье, внутригорье и высокогорье). Результаты. Ежегодно в Дагестане регистрируется в среднем 246,637,5 (MSD) случая АР на 100 000 населения. Показатель заболеваемости АР в условиях города достоверно выше у женщин (241,828,4 на 100000 населения), чем у мужчин (183,622,1). Заболеваемость мужчин сельской местности достоверно выше (261,062,9 на 100 000) по сравнению с показателем в городах Дагестана. В сельской местности существенно высокий уровень заболеваемости АР среди населения высокогорья (453,6179,9 на 100 000) по сравнению с показателем внутригорья (88,320,8). В неприморских городах заболеваемость АР женского населения существенно выше (394,5147,4 на 100 000), чем в приморских городах (195,442,9). Заключение. Факторами риска развития АР в условиях Дагестана являются женский пол, высокогорье и неприморские города.

Objective: to assess the incidence of allergic rhinitis (AR) in the male and female population of Dagestan, depending on the ecological zones. Material and methods. Comparative analysis of all registered cases (33,721 patients) of the Republic of Dagestan in 2014-2018. Patients are distributed by sex and place of residence (town, seaside, non-seaside, village, plain, foothills, between the mountains and highlands). Results. Annually in Dagestan, an average of 246.637.5 (MSD) cases of AR per 100,000 population are recorded. The incidence rate of AR in the town is significantly higher in women (241.828.4 per 100,000) than in men (183.622.1). The incidence of rural men is significantly higher (261.062.9 per 100,000) compared with the indicator in the towns of Dagestan. In rural areas, there is a significantly high incidence of AR in the high altitude population (453.6179.9 per 100,000) then between mountains (88.320.8). In non-coastal towns, the incidence of female ARs is significantly higher (394.5147.4 per 100,000) than in coastal towns (195.442.9). Findings. Risk factors for the development of AR in the conditions of Dagestan are the female sex, highlands and non-seaside towns.
Молекулярно-генетические аспекты онкологических заболеваний
Authors: М.О. Раджабов , Г.М. Раджабова , Е.Р. Азимова , О.М. Раджабов , М.Г. Атаев
Published: November 2024

Цель: В статье дан анализ молекулярных механизмов канцерогенеза. Подробно описана работа генетического аппарата клеток, обладающего сложной системой контроля деления, роста и дифференцировки клеток, то есть, регулирующей системы - протоонкогенов и генов-супрессоров опухолей, которая оказывает кардинальное влияние на процесс клеточной пролиферации. Показан механизм активации и инактивации определенных онкогенов и белков, обращено внимание, что причиной концерогенеза может быть также врождённый или приобретённый дефект систем репарации клеточной ДНК. Описаны основные свойства опухолевых клеток, приведены молекулярные причины опухолевого роста, указано на роль онкогенных РНК и ДНК содержащих вирусов в возникновении онкологических заболеваний. Заключение. Проведенный анализ показывает, что пусковым механизмом онкогенеза большинства новообразований являются нарушения генетического аппарата клетки. Существует значительный разрыв между научнообоснованными данными в области молекулярной генетики канцерогенеза и практическим применением их в работе врачей. Всвязи с этим создание новых методов ранней диагностики на основе молекулярно-генетических исследований и их широкая апробация позволят не только более глубоко изучить этиологические и патогенетические механизмы канцерогенеза, но и оптимизировать лечение пациентов с данной патологией.

Objective: The article provides an analysis of the molecular mechanisms of carcinogenesis. The work of the genetic apparatus of cells with a complex control system for cell division, growth and differentiation of cells, that is, the regulatory system of proto-oncogenes and tumor suppressor genes, which has a cardinal effect on the process of cell proliferation, is described in detail. The mechanism of activation and inactivation of certain oncogenes and proteins has been shown, attention has been paid to the fact that the cause of concertogenesis can also be a congenital or acquired defect in the cellular DNA repair systems. The main properties of tumor cells are described, the molecular causes of tumor growth are described, the role of oncogenic RNA and DNA-containing viruses in the onset of cancer is indicated. Cunclusion. The analysis shows that the triggering mechanism of oncogenesis of most neoplasms is a violation of the genetic apparatus of the cell. There is a significant gap between evidence-based data in the field of molecular genetics of carcinogenesis and their practical application in the work of doctors. In this regard, the creation of new methods of early diagnosis based on molecular genetic studies and their wide testing will not only allow a deeper study of the etiological and pathogenetic mechanisms of carcinogenesis, but also optimize the treatment of patients with this pathology.
Проблемы эпидемиологического надзора и контроля за шигeллезами
Authors: З.Г. Тагирова , А.С. Абусуева , З.М. Даниялбекова , Р.К. Алханов , И.Т. Шахбанов
Published: November 2024

Цель: обобщение литературных данных о региональных системах эпидемиологического надзора и контроля, основанного на понимании закономерностей возникновения и развития эпидемического и инфекционного процессов. Результаты. Острые кишечные инфекции (ОКИ) по-прежнему сохраняют в мире свою социальную и медицинскую значимость. Республика Дагестан является одной из неблагополучных территорий Российской Федерации по заболеваемости ОКИ, среди которых значительный удельный вес принадлежит бактериальной дизентерии. В структуре инфекционной заболеваемости ОКИ постоянно занимают второе место, после респираторно-вирусных заболеваний. За последние годы отмечается рост удельного веса кишечных инфекций в общей структуре инфекционой заболеваемости до (10,3) по республике. В публикации рассмотрены вопросы, связанные с совершенствованием эпидемиологического надзора и контроля заболеваемости шигеллезами на территориях с высокой активностью эпидемического процесса. Заключение. Проблема эпидемиологической и клинической диагностики, а также клинического мониторинга, направленного на выявление предикторов неблагоприятного течения и исходов шигеллезов требует дальнейшего изучения и принятия мер по профилактике ОКИ.

Objective. To synthesize literature data on regional systems of epidemiological surveillance and control, based on an understanding of the patterns of occurrence and development of epidemic and infectious processes. Acute intestinal infections (AEIs) still retain their social and medical significance in the world. The Republic of Dagestan is one of the disadvantaged territories of the Russian Federation for the incidence of acute intestinal infections, among which a significant proportion belongs to bacterial dysentery. In the structure of infectious morbidity, acute intestinal infections constantly take the second place after respiratory viral diseases. In recent years, there has been an increase in the proportion of intestinal infections in the general structure of infectious morbidity to (10.3) in the republic. The publication discusses issues related to the improvement of epidemiological surveillance and control over the incidence of shigellosis in territories with a high activity of the epidemic process. Conclusion. The problem of epidemiological and clinical diagnostics, as well as clinical monitoring aimed at identifying predictors of adverse course and outcomes of shigellosis, requires further study and adoption of measures to prevent acute intestinal infections.
Complex treatment of periodontitis with calcitrin and its effect for phosphorus-calcium metabolism
Authors: A.I. Abdurakhmanov , M.M. Salikhova , M.A. Dzhanbulatov , S.R. Salikhova , A.M. Dzhanbulatova , A.A. Nutsalova
Published: November 2024

Objective: to study the effect of calcitrin on calcium-phosphorus metabolism in the treatment of periodontitis. Material and methods. In 120 patients with periodontitis, the dynamics of complex treatment determined the activity of alkaline phosphatase, calcium and phosphorus, depending on various doses of calcitrin. Results. Traditional therapy of periodontitis promotes a short-term and insignificant increase in the activity of alkaline phosphatase in the blood serum of patients with periodontitis. The inclusion of calcitrin in a dose of 1-2 units in complex therapy increases the effectiveness of treatment. The best effect is achieved with a dose of 2 units of calcitrin. Conclusion. Calcitrin can be used in the complex treatment of severe periodontitis, when other methods of increasing and prolonging positive changes are not effective.
Pituitary nanism: epidemiological indicators in the Republic of Dagestan
Authors: E.M. Soltakhanov , I.B. Kostrova , N.A. Goncharova , G.A. Kairbekova
Published: November 2024

Objective: to study the epidemiological indicators of pituitary nanism (PN) in the Republic of Dagestan (RD). Materials and methods. The data of the state register of PN in the RD from 2008 to 2018 are analyzed. Results. Analysis and use of the epidemiological indicators of the incidence of PN allows us to predict and effectively apply the funds allocated for the rehabilitation of patients with PN. The use of standard methods for assessing physical development and federal recommendations for the diagnosis and management of patients with PN can reduce the number of false positive and false negative diagnoses. The distribution of morbidity and morbidity in the whole of the RD, in rural areas and cities was studied. Cunclusion. The epidemiological indicators of hypopituitarism in children remain at a fairly high level.
Endemic goiter – the consequence of the deficiency of iodine and selenium in the environment
Authors: M.A. Yakhyaev , Sh.K. Salikhov , M.G. Ataev , Z.G. Tagirova , Z.V. Kurbanovа
Published: November 2024

Objective: to identify the relationship between the concentration of trace elements of selenium and iodine in the objects of the Dagestan biosphere (soil, water sources, plants) and the incidence of endemic goiter of the population of the Republic, which will serve as a scientific basis for clarifying the ecological etiology of this human pathology and more targeted planning of preventive measures by health authorities. Materials and methods. Investigated soils, vegetation, natural water Kizlyar, Rutul, Tlyaratin districts of Dagestan. 5-6 key soil sections were laid on each type of soil. For the analysis of vegetation, the accounting plant sites with the size of 10x10 m (100 m2) were laid. The study of the chemical composition of the waters was conducted by the route of the expedition surveys. Water samples were taken in the summer months in vessels with a volume of 2 liters. Iodine and selenium content were determined in the samples. Iodine level was determined by microchemical method, selenium fluorometrically. Results. The incidence of endemic goiter for 13 years increased in a number of: Kizlyar, Tlyarata, Rutul districts, on average per 1000 population, in the studied areas, was for 2002-2013: in Kizlyar district 20.1, with a fluctuation of 15 to 25.2 in Rutul district 37.48 with a fluctuation of 31.6 - 49 in Tlyarata district 33.85 at a scale of 29.1-40.4. It is noted that the level of iodine and selenium content in soils, plants and water sources of the studied areas differs markedly. Moreover, the lower the content of iodine and selenium in the objects of study, the higher the incidence of endemic goiter. This pattern is confirmed by a significant negative correlation (r -0.87) of iodine and selenium concentrations in the objects of the Dagestan biosphere and the incidence of endemic goiter in the population. Cunclusion. The conducted research, indicating the correlation of iodine deficiency and selenium and the incidence of endemic goiter of the population, will help to study the ecological etiology of iodine deficiency diseases in the country.
Ethnic features of the incidence rheumatoid arthritis population Republic of Dagestan
Authors: Z.M. Saidova , Yu.M. Ataeva
Published: November 2024

Objective. Assessment of the incidence of rheumatoid arthritis (RA) of various ethnic populations of the Republic of Dagestan (RD). Materials and methods. The epidemiological study included all cases of arthritis (80 531 cases with the disease code according to ICD-10 M00-M14) and RA (41 141 cases with the code M05-M06) registered in the RD for 2014-2018. Results. An analysis of the ethnic composition of the population of the RD showed that more than 90 of representatives of one ethnic group (Avars, Dargins, Laks, Lezgins, Aguls) live mainly in mountainous areas in half of rural areas. The specific gravity of RA in the structure of arthritis ranged from 24.7 among Nogais to 84.0 among Rutuls. The average incidence rate of RA over 5 years among representatives of the Dargin, Lak and Rutul ethnic groups was above 1000 cases per 100,000 population, and among Tabasarans, Kumyks and Azerbaijanis below the level of 500 patients per 100,000 population. In 12 regions of the RD, the level of the disease of women exceeds the rate of men more than 2 times. The incidence rates of RA among men of Rutuls, Dargins, and Didos at working age were maximum, and among women of the same age, Dargin, Laк, and Rutul were the leaders. At retirement age, the maximum incidence of RA was observed in Dargin, Lak, and Rutul men, and in the female population, in Dargin, Lak, and Tabasaran. Conclusion. The results of the study demonstrated the importance of the ethnicity of the population, along with gender and age, as a risk factor in the development of autoimmune diseases of joints.
Use of Dagestan natural zeolites in medicine and veterinary medicine
Authors: BI. Shapiev , AA. Aliev , KB. Shapieva , ZS. Khambulatova
Published: November 2024

Objective: to study the ecological and pharmaco-toxicological properties of zeolites of mountainous Dagestan for their application in medicine and veterinary medicine. Materials and methods: On mice was conducted a toxicological study of the natural zeolites of the Levashinskys deposit in Dagestan. Results: A single dosing of zeolite in the stomach of a mouse in doses of 5, 8, 11, 14, 17 and 20 g per 1 kg of live weight did not cause visible changes in the general condition and behavior of the mice both on the days of introduction of the zeolite and in the following days.For 21 days of observation, the mice were in good condition and put on weight. Cunclusion: The results of our research show that zeolites of the Levashinskys deposit of mountainous Dagestan is not acutely toxic.