bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge Mapping of Homeowners’ Retrofit Behaviors: An Integrative Exploration
Authors: Liu Guo , Tan Yongtao , Huang Zhijia
Published: June 2021

Energy retrofitting of existing residential buildings has a great potential to achieve a sustainable future. One important way to reach this potential is to understand homeowners’ retrofit behaviors due to their crucial roles in retrofit adoption and retrofit effects. Despite many attempts, researchers and governments still know less about the holistic profile of homeowners’ retrofit behaviors, which brought little success in trigging renovation activities and achieving expected retrofit effects. This study tries to fill this research gap by a comprehensive review of the body of existing research. A keyword-based scientometric analysis was performed based on a set of 152 journal articles. By further refining keywords, main research domains pertaining to investment-decision-energy behaviors, policy instruments, retrofit types, construction & services, and methods & methodologies were mapped to show relevant research knowledge and research topics. Based on these research results, a further integrated framework was developed, which explains homeowners’ retrofit behaviors in a systematic way of cross-disciplinary knowledge interactions. Furthermore, implications for retrofit policies in existing buildings were provided. This study is useful for facilitating future research to deepen homeowners’ retrofit behaviors, and also provides valuable references for policy makers to successfully promote home energy retrofit.
Influence of Phase Composition and Pretreatment on the Conversion of Iron Oxides into Iron Carbides in Syngas Atmospheres
Authors: Arinchtein Aleks , Ye Meng-Yang , Geske Michael , Frisch Marvin , Kraehnert Ralph
Published: June 2021

CO2 Fischer–Tropsch synthesis (CO2–FTS) is a promising technology enabling conversion of CO2 into valuable chemical feedstocks via hydrogenation. Iron–based CO2–FTS catalysts are known for their high activities and selectivities towards the formation of higher hydrocarbons. Importantly, iron carbides are the presumed active phase strongly associated with the formation of higher hydrocarbons. Yet, many factors such as reaction temperature, atmosphere, and pressure can lead to complex transformations between different oxide and/or carbide phases, which, in turn, alter selectivity. Thus, understanding the mechanism and kinetics of carbide formation remains challenging. We propose model–type iron oxide films of controlled nanostructure and phase composition as model materials to study carbide formation in syngas atmospheres. In the present work, different iron oxide precursor films with controlled phase composition (hematite, ferrihydrite, maghemite, maghemite/magnetite) and ordered mesoporosity are synthesized using the evaporation–induced self–assembly (EISA) approach. The model materials are then exposed to a controlled atmosphere of CO/H2 at 300 °C. Physicochemical analysis of the treated materials indicates that all oxides convert into carbides with a core–shell structure. The structure appears to consist of crystalline carbide cores surrounded by a partially oxidized carbide shell of low crystallinity. Larger crystallites in the original iron oxide result in larger carbide cores. The presented simple route for the synthesis and analysis of soft–templated iron carbide films will enable the elucidation of the dynamics of the oxide to carbide transformation in future work.
Experimental Study on Sulfur Deactivation and Regeneration of Ni-Based Catalyst in Dry Reforming of Biogas
Authors: Chein Rei-Yu , Chen Yen-Chung , Chen Wei-Hsin
Published: June 2021

The dry reforming of methane (DRM) using biogas and a Ni-based catalyst for syngas production was studied experimentally in this study under the presence of H2S. Using the nonpoisoned DRM performance as a comparison basis, it was found that the catalyst deactivation by the sulfur chemisorption onto the catalyst surface depends on both reaction temperature and time. With low reaction temperatures, a complete sulfur coverage was resulted and could not be regenerated. With higher reaction temperatures, the H2S coverage decreased, and the poisoned catalysts could be regenerated. The experimental results also indicated that a catalyst deactivation could not be avoided by using the bi-reforming of methane by adding O2 or H2O simultaneously in the reactant due to the stronger chemisorption capability of sulfur. The catalyst could only be regenerated after it was poisoned. The experimental results indicated that the high-temperature oxidation process was the most effective process for regenerating the poisoned catalyst.
Altering the Stereoselectivity of Whole-Cell Biotransformations via the Physicochemical Parameters Impacting the Processes
Authors: Raczyńska Agnieszka , Jadczyk Joanna , Brzezińska-Rodak Małgorzata
Published: June 2021

The enantioselective synthesis of organic compounds is one of the great challenges in organic synthetic chemistry due to its importance for the acquisition of biologically active derivatives, e.g., pharmaceuticals, agrochemicals, and others. This is why biological systems are increasingly applied as tools for chiral compounds synthesis or modification. The use of whole cells of “wild-type” microorganisms is one possible approach, especially as some methods allow improving the conversion degrees and controlling the stereoselectivity of the reaction without the need to introduce changes at the genetic level. Simple manipulation of the culture conditions, the form of a biocatalyst, or the appropriate composition of the biotransformation medium makes it possible to obtain optically pure products in a cheap, safe, and environmentally friendly manner. This review contains selected examples of the influence of physicochemical factors on the stereochemistry of the biocatalytic preparation of enantiomerically pure compounds, which is undertaken through kinetically controlled separation of their racemic mixtures or reduction of prochiral ketones and has an effect on the final enantiomeric purity and enantioselectivity of the reaction.
A Review on the Treatment of Petroleum Refinery Wastewater Using Advanced Oxidation Processes
Authors: Elmobarak Wamda Faisal , Hameed Bassim H. , Almomani Fares , Abdullah Ahmad Zuhairi
Published: June 2021

The petroleum industry is one of the most rapidly developing industries and is projected to grow faster in the coming years. The recent environmental activities and global requirements for cleaner methods are pushing the petroleum refining industries for the use of green techniques and industrial wastewater treatment. Petroleum industry wastewater contains a broad diversity of contaminants such as petroleum hydrocarbons, oil and grease, phenol, ammonia, sulfides, and other organic composites, etc. All of these compounds within discharged water from the petroleum industry exist in an extremely complicated form, which is unsafe for the environment. Conventional treatment systems treating refinery wastewater have shown major drawbacks including low efficiency, high capital and operating cost, and sensitivity to low biodegradability and toxicity. The advanced oxidation process (AOP) method is one of the methods applied for petroleum refinery wastewater treatment. The objective of this work is to review the current application of AOP technologies in the treatment of petroleum industry wastewater. The petroleum wastewater treatment using AOP methods includes Fenton and photo-Fenton, H2O2/UV, photocatalysis, ozonation, and biological processes. This review reports that the treatment efficiencies strongly depend on the chosen AOP type, the physical and chemical properties of target contaminants, and the operating conditions. It is reported that other mechanisms, as well as hydroxyl radical oxidation, might occur throughout the AOP treatment and donate to the decrease in target contaminants. Mainly, the recent advances in the AOP treatment of petroleum wastewater are discussed. Moreover, the review identifies scientific literature on knowledge gaps, and future research ways are provided to assess the effects of these technologies in the treatment of petroleum wastewater.
Microwave-Catalyzed Conversion of Phenolic Resin Waste to Activated Carbon and Its Applications for Removing Ammonium from Water
Authors: Kuan Wen-Hui , Hu Yi-Show , Chiu Chen-Yi , Hung Kuo-Yung , Chou Shan-Shan
Published: June 2021

The influences of reactive and dielectric characteristics of activators were investigated in the microwave-catalyzed conversion of phenolic resin waste to activated carbon (AC). To compare with the dielectric interactions of the microwaves with treated samples, conventional electric heating for AC carbonization was also conducted in parallel. The porosity and chemical features of the prepared AC were examined, and the AC was used to remove ammonium from water through adsorption. The results revealed that KOH-activated wastes developed a highly porous structure, whereas H3PO4 treated wastes were functionalized with surficial phosphate groups. Both of these features were more pronounced in the cases of microwave-catalyzed carbonization than those using conventional electric heating. Because of the intense dielectric interactions of the H3PO4-activated waste with microwave, the abundant phosphate functional groups formed on the phenolic resin waste surface during microwave-catalyzed carbonization. They facilitated the resulting AC as an effective adsorbent for aqueous ammonium.
Two-Dimensional Layered NiLiP2S6 Crystals as an Efficient Bifunctional Electrocatalyst for Overall Water Splitting
Authors: Huang Song-Jeng , Muneeb Adil , Sabhapathy Palani , Bayikadi Khasim Saheb , Murtaza Tahir , Raju Kalaivanan , Chen Li-Chyong , Chen Kuei-Hsien , Sankar Raman
Published: June 2021

The quest of earth-abundant bifunctional electrocatalysts for highly efficient oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) is essential for clean and renewable energy systems. Herein, directed by the experimental analysis, we demonstrate layered nickel lithium phosphosulfide (NiLiP2S6) crystal as a highly efficient water-splitting catalyst in alkaline media. With strained lattice due to stacked layers as observed by TEM and electronic structure analysis performed by XPS showed mixed Ni2+,3+ oxidation states induced by addition of Li as a cation, NiLiP2S6 displays excellent OER (current density of 10 mA cm–2 showed an overpotential of 303 mV vs. RHE and a Tafel slope of 114 mV dec–1) and HER activity (current density of −10 mA cm–2 showed an overpotential of 184 mV vs. RHE and a Tafel slope of 94.5 mV dec–1). Finally, an alkaline media was employed to demonstrate the overall water splitting using NiLiP2S6 as both the anode and the cathode, which attained a 50 mA cm−2 current density at 1.68 V. This bimetallic phosphosulfide, together with long-term stability and enhanced intrinsic activity, shows enormous potential in water splitting applications.
B Cells in Neuroinflammation: New Perspectives and Mechanistic Insights
Authors: Ahn Julie J. , Abu-Rub Mohammad , Miller Robert H.
Published: June 2021

In recent years, the role of B cells in neurological disorders has substantially expanded our perspectives on mechanisms of neuroinflammation. The success of B cell-depleting therapies in patients with CNS diseases such as neuromyelitis optica and multiple sclerosis has highlighted the importance of neuroimmune crosstalk in inflammatory processes. While B cells are essential for the adaptive immune system and antibody production, they are also major contributors of pro- and anti-inflammatory cytokine responses in a number of inflammatory diseases. B cells can contribute to neurological diseases through peripheral immune mechanisms, including production of cytokines and antibodies, or through CNS mechanisms following compartmentalization. Emerging evidence suggests that aberrant pro- or anti-inflammatory B cell populations contribute to neurological processes, including glial activation, which has been implicated in the pathogenesis of several neurodegenerative diseases. In this review, we summarize recent findings on B cell involvement in neuroinflammatory diseases and discuss evidence to support pathogenic immunomodulatory functions of B cells in neurological disorders, highlighting the importance of B cell-directed therapies.
Honokiol Affects Stem Cell Viability by Suppressing Oncogenic YAP1 Function to Inhibit Colon Tumorigenesis
Authors: Subramaniam Dharmalingam , Ponnurangam Sivapriya , Ramalingam Satish , Kwatra Deep , Dandawate Prasad , Weir Scott J. , Umar Shahid , Jensen Roy A. , Anant Shrikant
Published: June 2021

Honokiol (HNK) is a biphenolic compound that has been used in traditional medicine for treating various ailments, including cancers. In this study, we determined the effect of HNK on colon cancer cells in culture and in a colitis-associated cancer model. HNK treatment inhibited proliferation and colony formation while inducing apoptosis. In addition, HNK suppressed colonosphere formation. Molecular docking suggests that HNK interacts with reserve stem cell marker protein DCLK1, with a binding energy of −7.0 Kcal/mol. In vitro kinase assays demonstrated that HNK suppressed the DCLK1 kinase activity. HNK also suppressed the expression of additional cancer stem cell marker proteins LGR5 and CD44. The Hippo signaling pathway is active in intestinal stem cells. In the canonical pathway, YAP1 is phosphorylated at Ser127 by upstream Mst1/2 and Lats1/2. This results in the sequestration of YAP1 in the cytoplasm, thereby not allowing YAP1 to translocate to the nucleus and interact with TEAD1-4 transcription factors to induce gene expression. However, HNK suppressed Ser127 phosphorylation in YAP1, but the protein remains sequestered in the cytoplasm. We further determined that this occurs by YAP1 interacting with PUMA. To determine if this also occurs in vivo, we performed studies in an AOM/DSS induced colitis-associated cancer model. HNK administered by oral gavage at a dose of 5mg/kg bw for 24 weeks demonstrated a significant reduction in the expression of YAP1 and TEAD1 and in the stem marker proteins. Together, these data suggest that HNK prevents colon tumorigenesis in part by inducing PUMA-YAP1 interaction and cytoplasmic sequestration, thereby suppressing the oncogenic YAP1 activity.
Ceramic Tile Adhesives from the Producer’s Perspective: A Literature Review
Authors: Michalak Jacek
Published: June 2021

Ceramic tiles and ceramic tile adhesives (CTA) are two impressive materials that have changed construction history. Ceramic tiles could not provide their beauty and durability for buildings when used as a covering both for the inside and exterior finishing without CTA. Nowadays, they are complex multi-component systems. Among the various CTAs, cementitious products are the most commonly used. This article presents an extensive review of the literature, showing how they are perceived in the scientific literature today. In this paper, an attempt is made to review individual adhesives’ ingredients’ effects on their properties, with particular reference to redispersible polymer powders and methylcellulose ethers. The article presents the basics of the CTAs, assessing and verifying the constancy of their performance in force in European Union countries. Furthermore, it gives a critical review of CTA’s normalized measurement methodologies. The study also draws attention to the need to consider measurement uncertainty in decision-making and conformity assessment, supported by an analysis of the results of multi-annual inter-laboratory studies and market surveillance tests. Future research suggestions are also made based on the review, mainly from the adhesive manufacturer’s perspective.
Elaboration by Wrapping Process and Multiscale Characterisation of Thermoplastic Bio-Composite Based on Hemp/PA11 Constituents
Authors: Laqraa Chaimae , Ferreira Manuela , Rashed Labanieh Ahmad , Soulat Damien
Published: June 2021

The present work investigates the potential of developing bio-composites based on thermoplastic polymers reinforced with natural fibres by using hybrid yarns. The hybrid yarns were produced by the wrapping technique, in which a multifilament of polyamide 11 (PA11) was wrapped around an untreated low-twisted hemp roving to produce a yarn with sufficient tenacity and stiffness for the next step of weaving. The tensile behaviour of the wrapped yarns was identified both in the dry- and thermo-state. Then, two different fabrics were woven and tested to study the influence of yarn densities and weave diagrams on the tensile and flexural properties. At this fabric scale, properties of fabrics made from hybrid yarns were compared with those of fabrics from a previous study made from 100% hemp roving. Composites made from these fabrics, with stacking of two cross-plies, were produced by thermocompression and characterised regarding mechanical strength.
Topology Optimization of Hard-Coating Thin Plate for Maximizing Modal Loss Factors
Authors: Luo Haitao , Chen Rong , Guo Siwei , Fu Jia
Published: June 2021

At present, hard coating structures are widely studied as a new passive damping method. Generally, the hard coating material is completely covered on the surface of the thin-walled structure, but the local coverage cannot only achieve better vibration reduction effect, but also save the material and processing costs. In this paper, a topology optimization method for hard coated composite plates is proposed to maximize the modal loss factors. The finite element dynamic model of hard coating composite plate is established. The topology optimization model is established with the energy ratio of hard coating layer to base layer as the objective function and the amount of damping material as the constraint condition. The sensitivity expression of the objective function to the design variables is derived, and the iteration of the design variables is realized by the Method of Moving Asymptote (MMA). Several numerical examples are provided to demonstrate that this method can obtain the optimal layout of damping materials for hard coating composite plates. The results show that the damping materials are mainly distributed in the area where the stored modal strain energy is large, which is consistent with the traditional design method. Finally, based on the numerical results, the experimental study of local hard coating composites plate is carried out. The results show that the topology optimization method can significantly reduce the frequency response amplitude while reducing the amount of damping materials, which shows the feasibility and effectiveness of the method.
Deposition of Potentially Toxic Metals in the Soil from Surrounding Cement Plants in a Karst Area of Southeastern Brazil
Authors: Silva Thiago Augusto da Costa , Paula Marcos de , Silva Washington Santos , Lacorte Gustavo Augusto
Published: June 2021

Cement factories are the main sources of environmental pollutants among the different industrial activities, including soil contamination by potentially toxic metals. The karst region of Southeastern Brazil is known for the implementation of large cement producing facilities. This study aims to evaluate whether there is an increase in the concentration of PTM in the soil surrounding the cement plants and to estimate their harmfulness to both local human population and environment. In total, 18 soil samples were collected from the surroundings of three cement plants as well as four soil samples from areas outside the influence of cement plants and concentration of the following potentially toxic metals (PTM) were estimated: Cd, Pb, Co, Cu, Cr, Mn, Ni, and Zn. The results revealed that all PTM concentrations from cement plant surroundings were significantly higher than PTM concentrations from control areas and no PTM concentrations from CPS or CA soil samples exceeded national and global contamination thresholds. However, Igeo Index indicated low level soil contamination by Pb, Cu, and Cr, as well as high levels for Co. We could not verify significant non-carcinogenic risk to health for any soil sample, but carcinogenic risk analysis revealed different levels of carcinogenic risk among the sampled locations, for both adults and children. Our results indicate that exclusively evaluating the concentration of potentially toxic metals is not enough to verify the potential harmful effects of cement production for the surrounding population. Here we evidence that additional indices, based on both contamination indices and health risk assessments, should be considered for better evaluation of the impacts of cement production activity.
Quality Control of Vitamins A and E and Coenzyme Q10 in Commercial Anti-Ageing Cosmetic Products
Authors: Temova Rakuša Žane , Roškar Robert
Published: June 2021

Vitamins A and E and coenzyme Q10 are common ingredients in anti-ageing cosmetic products. Within this study, we evaluated the quality of commercial cosmetics with vitamin A (35 products), vitamin E (49 products), and coenzyme Q10 (27 products) by using validated HPLC–UV methods. Vitamin A was determined as retinol, retinyl palmitate, retinyl propionate, β carotene, and hydroxypinacolone retinoate in concentrations ranging from 950 ng/g to 19 mg/g. Total vitamin A contents, expressed with retinol equivalents, ranged from 160 ng/g to 19 mg/g, and were above the maximum concentration recommended by the SCCS in six of the 35 tested cosmetics. The content-related quality control of 10 cosmetics with specified vitamin A content revealed significant deviations (between 0% and 400%) of the label claim. Vitamin E was determined as both tocopherol and tocopheryl acetate in concentrations between 8.5 µg/g and 16 mg/g. Coenzyme Q10 was determined as ubiquinone in 24 tested cosmetics, which labelled it, in concentrations between 4.2 µg/g and 100 µg/g. Labelling irregularities were observed in all three active compound groups, resulting in a significant share (42%) of improperly labelled cosmetic products. The results of this study reveal the need for stricter cosmetics regulation and highlight the importance of their quality control, especially by evaluating the contents of the active compounds, in their efficacy and safety assurance.
Is Reduced Strontium Titanate a Semiconductor or a Metal?
Authors: Rodenbücher Christian , Guguschev Christo , Korte Carsten , Bette Sebastian , Szot Kristof
Published: June 2021

In recent decades, the behavior of SrTiO3 upon annealing in reducing conditions has been under intense academic scrutiny. Classically, its conductivity can be described using point defect chemistry and predicting n-type or p-type semiconducting behavior depending on oxygen activity. In contrast, many examples of metallic behavior induced by thermal reduction have recently appeared in the literature, challenging this established understanding. In this study, we aim to resolve this contradiction by demonstrating that an initially insulating, as-received SrTiO3 single crystal can indeed be reduced to a metallic state, and is even stable against room temperature reoxidation. However, once the sample has been oxidized at a high temperature, subsequent reduction can no longer be used to induce metallic behavior, but semiconducting behavior in agreement with the predictions of point defect chemistry is observed. Our results indicate that the dislocation-rich surface layer plays a decisive role and that its local chemical composition can be changed depending on annealing conditions. This reveals that the prediction of the macroscopic electronic properties of SrTiO3 is a highly complex task, and not only the current temperature and oxygen activity but also the redox history play an important role.
Study of Corrosion Resistance and Degradation Mechanisms in LiTiO2-Li2TiO3 Ceramic
Authors: Shlimas Dmitriy , Kozlovskiy Artem L. , Zdorovets Maxim
Published: June 2021

The interest in lithium-containing ceramics is due to their huge potential as blanket materials for thermonuclear reactors for the accumulation of tritium. However, an important factor in their use is the preservation of the stability of their strength and structural properties when under the influence of external factors that determine the time frame of their operation. This paper presents the results of a study that investigated the influence of the LiTiO2 phase on the increasing resistance to degradation and corrosion of Li2TiO3 ceramic when exposed to aggressive acidic media. Using the X-ray diffraction method, it was found that an increase in the concentration of LiClO4·3H2O during synthesis leads to the formation of a cubic LiTiO2 phase in the structure as a result of thermal sintering of the samples. During corrosion tests, it was found that the presence of the LiTiO2 phase leads to a decrease in the degradation rate in acidic media by 20–70%, depending on the concentration of the phase. At the same time, and in contrast to the samples of Li2TiO3 ceramics, for which the mechanisms of degradation during a long stay in aggressive media are accompanied by large mass losses, for the samples containing the LiTiO2 phase, the main degradation mechanism is pitting corrosion with the formation of pitting inclusions.
Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection
Authors: Mir Taskia , Pond Gregory , Greenspoon Jeffrey N.
Published: June 2021

(1) Background: Studies in elderly patients over the age of 65 with glioblastoma have shown survival benefits of short-course radiation therapy with concurrent and adjuvant temozolomide, making it the standard of care adopted at Juravinski Cancer Center. Our study retrospectively examines patients with GBM aged ≥ 70 at the JCC treated with short-course radiation alone compared to those treated with short-course radiation and concurrent and adjuvant TMZ, to determine if there is a difference in outcomes based on performance status. (2) Methods: A retrospective chart review was conducted at JCC using patients diagnosed with GBM in 2014–2017 (treated with the old protocol of short-course RT alone) versus those diagnosed in 2017–2019 (treated with the new protocol of short-course radiation and TMZ). Patient demographics, treatments, outcomes, and baseline KPS were analyzed. (3) Results: No clear benefit and more neurologic decline post treatment were seen in patients with borderline performance status and subtotal resection who underwent concurrent treatment with temozolomide and radiation. The addition of temozolomide was most helpful in patients with good performance status and a gross total resection. Variable outcomes were seen in patients with mixed traits. (4) Conclusions: This study suggests that performance status and extent of resection are significant determinants of patient response to treatment. In the case of elderly patients with borderline performance status and GTR or those with good performance status and STR, also described as “mixed traits”, it may be beneficial to pursue single modality treatment, ideally based on MGMT promoter methylation status as opposed to bimodality treatment in order to maintain the best QOL.
An Annotated Corpus of Crime-Related Portuguese Documents for NLP and Machine Learning Processing
Authors: Carnaz Gonçalo , Antunes Mário , Nogueira Vitor Beires
Published: June 2021

Criminal investigations collect and analyze the facts related to a crime, from which the investigators can deduce evidence to be used in court. It is a multidisciplinary and applied science, which includes interviews, interrogations, evidence collection, preservation of the chain of custody, and other methods and techniques of investigation. These techniques produce both digital and paper documents that have to be carefully analyzed to identify correlations and interactions among suspects, places, license plates, and other entities that are mentioned in the investigation. The computerized processing of these documents is a helping hand to the criminal investigation, as it allows the automatic identification of entities and their relations, being some of which difficult to identify manually. There exists a wide set of dedicated tools, but they have a major limitation: they are unable to process criminal reports in the Portuguese language, as an annotated corpus for that purpose does not exist. This paper presents an annotated corpus, composed of a collection of anonymized crime-related documents, which were extracted from official and open sources. The dataset was produced as the result of an exploratory initiative to collect crime-related data from websites and conditioned-access police reports. The dataset was evaluated and a mean precision of 0.808, recall of 0.722, and F1-score of 0.733 were obtained with the classification of the annotated named-entities present in the crime-related documents. This corpus can be employed to benchmark Machine Learning (ML) and Natural Language Processing (NLP) methods and tools to detect and correlate entities in the documents. Some examples are sentence detection, named-entity recognition, and identification of terms related to the criminal domain.
BROAD—A Benchmark for Robust Inertial Orientation Estimation
Authors: Laidig Daniel , Caruso Marco , Cereatti Andrea , Seel Thomas
Published: June 2021

Inertial measurement units (IMUs) enable orientation, velocity, and position estimation in several application domains ranging from robotics and autonomous vehicles to human motion capture and rehabilitation engineering. Errors in orientation estimation greatly affect any of those motion parameters. The present work explains the main challenges in inertial orientation estimation (IOE) and presents an extensive benchmark dataset that includes 3D inertial and magnetic data with synchronized optical marker-based ground truth measurements, the Berlin Robust Orientation Estimation Assessment Dataset (BROAD). The BROAD dataset consists of 39 trials that are conducted at different speeds and include various types of movement. Thereof, 23 trials are performed in an undisturbed indoor environment, and 16 trials are recorded with deliberate magnetometer and accelerometer disturbances. We furthermore propose error metrics that allow for IOE accuracy evaluation while separating the heading and inclination portions of the error and introduce well-defined benchmark metrics. Based on the proposed benchmark, we perform an exemplary case study on two widely used openly available IOE algorithms. Due to the broad range of motion and disturbance scenarios, the proposed benchmark is expected to provide valuable insight and useful tools for the assessment, selection, and further development of inertial sensor fusion methods and IMU-based application systems.
Rare TERT Promoter Mutations Present in Benign and Malignant Cutaneous Vascular Tumors
Authors: Jansen Philipp , Lodde Georg Christian , Zaremba Anne , Thielmann Carl Maximilian , Matull Johanna , Müller Hansgeorg , Möller Inga , Sucker Antje , Esser Stefan , Schaller Jörg , Schadendorf Dirk , Mentzel Thomas , Hadaschik Eva , Griewank Klaus Georg
Published: June 2021

Mutations in the promoter of the telomerase reverse transcriptase (TERT) gene have been described as the most common hot-spot mutations in different solid tumors. High frequencies of TERT promoter mutations have been reported to occur in tumors arising in tissues with low rates of self-renewal. For cutaneous vascular tumors, the prevalence of TERT promoter mutations has not yet been investigated in larger mixed cohorts. With targeted next-generation sequencing (NGS), we screened for different known recurrent TERT promoter mutations in various cutaneous vascular proliferations. In our cohort of 104 representative cutaneous vascular proliferations, we identified 7 TERT promoter mutations. We could show that 4 of 64 (6.3%) hemangiomas and vascular malformations harbored TERT promoter mutations (1 Chr.5:1295228 C > T mutations, 1 Chr.5:1295228_9 CC > TT mutation, and 2 Chr.5:1295250 C > T mutations), 1 of 19 (5.3%) angiosarcomas harbored a Chr.5:1295250 C > T TERT promoter mutation, and 2 of 21 (9.5%) Kaposi’s sarcomas harbored TERT promoter mutations (2 Chr.5:1295250 C > T mutations). To our knowledge, this is the first general description of the distribution of TERT promoter mutations in a mixed cohort of cutaneous vascular tumors, revealing that TERT promoter mutations seem to occur with low prevalence in both benign and malignant cutaneous vascular proliferations.
Kurtosis-Based Symbol Timing and Carrier Phase/Frequency Tracking
Authors: Moon Todd K. , Gunther Jacob H.
Published: June 2021

Kurtosis is known to be effective at estimating signal timing and carrier phase offset when the processing is performed in a “burst mode,” that is, operating on a block of received signal in an offline fashion. In this paper, kurtosis-based estimation is extended to provide tracking of timing and carrier phase, and frequency offsets. The algorithm is compared with conventional PLL-type timing/phase estimation and shown to be superior in terms of speed of convergence, with comparable variance in the matched filter output symbols.
Human-Mimetic Estimation of Food Volume from a Single-View RGB Image Using an AI System
Authors: Yang Zhengeng , Yu Hongshan , Cao Shunxin , Xu Qi , Yuan Ding , Zhang Hong , Jia Wenyan , Mao Zhi-Hong , Sun Mingui
Published: June 2021

It is well known that many chronic diseases are associated with unhealthy diet. Although improving diet is critical, adopting a healthy diet is difficult despite its benefits being well understood. Technology is needed to allow an assessment of dietary intake accurately and easily in real-world settings so that effective intervention to manage being overweight, obesity, and related chronic diseases can be developed. In recent years, new wearable imaging and computational technologies have emerged. These technologies are capable of performing objective and passive dietary assessments with a much simplified procedure than traditional questionnaires. However, a critical task is required to estimate the portion size (in this case, the food volume) from a digital image. Currently, this task is very challenging because the volumetric information in the two-dimensional images is incomplete, and the estimation involves a great deal of imagination, beyond the capacity of the traditional image processing algorithms. In this work, we present a novel Artificial Intelligent (AI) system to mimic the thinking of dietitians who use a set of common objects as gauges (e.g., a teaspoon, a golf ball, a cup, and so on) to estimate the portion size. Specifically, our human-mimetic system “mentally” gauges the volume of food using a set of internal reference volumes that have been learned previously. At the output, our system produces a vector of probabilities of the food with respect to the internal reference volumes. The estimation is then completed by an “intelligent guess”, implemented by an inner product between the probability vector and the reference volume vector. Our experiments using both virtual and real food datasets have shown accurate volume estimation results.
Defence Is a Priority in Female Juveniles and Adults of Taxus baccata L.
Authors: Nowak Kinga , Giertych Marian J. , Pers-Kamczyc Emilia , Thomas Peter A. , Iszkuło Grzegorz
Published: June 2021

Female individuals of dioecious plants invest their resources more in storage and defence, and the males have higher nitrogen content invested in the production of pollen grains. An unresolved problem is whether this strategy occurs only in sexually mature plants or can also occur in juvenile plants. To answer this, Taxus baccata (L.) needles from the mature plants and rooted cuttings (juveniles) in a pot experiment were compared for the content of carbon, nitrogen, starch, total non-structural carbohydrates (TNC), and total phenolic compounds (TPhC). The results indicate that the differences between sexes occurred mainly in sexually mature plants, where the starch content was higher in females and nitrogen in males. However, the novelty of the results is that TPhC was generally higher in females than males in both adults and juveniles, suggesting that defence is a priority for females from an early age. We do not know if this is an innate trait because the strobili production (albeit at a very low level) of juveniles was observed in all individuals after the autumn of the first year. We found no effect of fertilization on sex-specific response in the pot experiment, which may be related to the lower reproductive effort of juveniles.
Construction and Optimization of an Urban Ecological Security Pattern Based on Habitat Quality Assessment and the Minimum Cumulative Resistance Model in Shenzhen City, China
Authors: Zhang Yu-Zhe , Jiang Zhi-Yun , Li Yang-Yang , Yang Zhi-Guang , Wang Xiao-Hong , Li Xian-Bing
Published: June 2021

The rapid development of urbanization has caused many ecological issues and greatly threatened the sustainable development of human society. The construction of ecological security patterns (ESPs) offers an effective way to balance ecological conservation and urbanization. This study aimed to take the highly urbanized city of Shenzhen, China, as a study area to construct an urban ESP and put forward suggestions for the urban development of ecological security. Ecological sources were identified through the Habitat Quality module in the InVEST model, and ecological corridors, strategic ecological nodes, and stepping-stone patches were extracted based on the minimum cumulative resistance (MCR) model. These elements together constituted the ESP. In particular, with the results of the continuous decline in the overall habitat quality, this study identified ten ecological sources with superior habitat quality, mainly distributed in rural woodlands, in urban green land, and in forest park patches. An optimized pattern for Shenzhen City with one axis, three belts, and four zones is proposed, with the study area divided into an ecological preservation zone, a limited development zone, an optimized development zone, and a key development zone. Moreover, forty-five ecological corridors were extracted and graded into three levels, presenting a spatial pattern of one axis and three belts. The appropriate widths of these ecological corridors were suggested to be between 30 and 60 m in Shenzhen City. In addition, we identified twenty-five ecological nodes, sixteen ecological fracture points, and sixteen stepping stones to improve the maintenance and construction of the ecological corridor network. More generally, this study demonstrates a scientific approach to identifying ESPs based on habitat quality, and can serve as a reference for the planning of urban ecological function regionalization.
The Effect of Controlled-Release Carvacrol on Safety and Quality of Blueberries Stored in Perforated Packaging
Authors: Sun Xiuxiu , Cameron Randall G. , Plotto Anne , Zhong Tian , Ference Christopher M. , Bai Jinhe
Published: June 2021

The objective of this research was to evaluate the use of a controlled-release carvacrol powder to delay storage decay and maintain the safety of blueberries. The controlled-release carvacrol powder was a microcapsule of carvacrol (11% (w/w) active carvacrol) surrounded by a pectin/sodium alginate matrix. The microcapsules were packed in an air-permeable pouch, and then attached to the top of a clamshell filled with blueberries. The blueberries, inoculated with Escherichia coli or Colletotrichum acutatum, or non-inoculated control, were monitored for microbial growth and quality for 10 days at 10 °C and 5 days at 20 °C. Three treatments were compared: controlled-release microencapsulated carvacrol, non-encapsulated carvacrol, and control. The results showed that both the microencapsulated carvacrol and the non-encapsulated carvacrol treatments significantly reduced the populations of yeast and mold, and of E. coli and mesophilic aerobic bacteria. The microencapsulated carvacrol treated berries retained better quality due to significantly lower weight loss than control after 10 days at 10 °C. Sensory panelists found that the microencapsulated carvacrol berries had significantly higher overall blueberry flavor and lower discernible off-flavor in comparison with the non-encapsulated treatment after 3 days at 20 °C. The fruit internal quality, including total soluble solids content (SSC), and titratable acidity (TA), was not significantly affected by any treatment. These results indicate that pectin/sodium alginate controlled-release microencapsulated carvacrol can be used for the preservation of blueberries or other small fruit.
Reduction of the Heterocyclic Amines in Grilled Beef Patties through the Combination of Thermal Food Processing Techniques without Destroying the Grilling Quality Characteristics
Authors: Wang Wei , Dong Lu , Zhang Yan , Yu Huaning , Wang Shuo
Published: June 2021

In order to reduce the formation of heterocyclic amines in grilled beef patties without destroying their unique quality characteristics, the effects of different thermal processes, including charcoal grilling, infrared grilling, superheated steam roasting and microwave heating, on the production of heterocyclic amines in beef patties and grilling quality characteristics were systematically analyzed. The results showed that infrared grilling can significantly (p < 0.05) reduce the content of heterocyclic amines in grilled patties, and the combination of microwave heating or superheated steam roasting with infrared grilling could further reduce the content of heterocyclic amines, with a maximum reduction ratio of 44.48%. While subtle differences may exist in infrared grilled patties with/without superheated steam roasting or microwave heating, a slight change will not affect the overall quality characteristics of grilled patties. The combined thermal processing will not visually affect the color of the grilled patties. Correlation analysis and regression analysis showed that the reduction in heterocyclic amines caused by microwave heating and superheated steam roasting are related to the moisture content and lipid oxidation of grilled patties, respectively. Using combined thermal processes to reduce the formation of heterocyclic amines is advisable.
First Study on Ammonia Spray Characteristics with a Current GDI Engine Injector
Authors: Pelé Ronan , Mounaïm-Rousselle Christine , Bréquigny Pierre , Hespel Camille , Bellettre Jérôme
Published: June 2021

Using carbon free energy sources is one of the keys to mitigate climate change. Hydrogen promises to be one of these carbon free energies, but its storage is difficult and expensive. Ammonia, however, is interesting as it can store hydrogen safely and can be used in combustion engines instead of hydrocarbon fuels. In this experimental work, the spray characteristics of ammonia under different air densities and temperatures were investigated in constant volume and were compared to a biofuel, ethanol, and a common fuel, gasoline. The Schlieren technique was used to capture images of liquid and liquid + vapor spray. The penetration length, the angle near the injector and the angle at half-penetration length were measured. The results show that the spray geometry of ammonia differs from that of the other fuels and that its sensitivity to air density and temperature is greater. The flash boiling condition at ambient temperature was explored for ammonia and indicated a wider spray at half-penetration length at phase change. Moreover, a semi-empirical correlation for penetration length as a function of physical parameters was found with a high accuracy for the global spray. These experimental data provide the first information about ammonia injection with a current spark-ignition GDI injector.
Scaling in a Geothermal Heat Exchanger at Soultz-Sous-Forêts (Upper Rhine Graben, France): A XRD and SEM-EDS Characterization of Sulfide Precipitates
Authors: Ledésert Béatrice A. , Hébert Ronan L. , Mouchot Justine , Bosia Clio , Ravier Guillaume , Seibel Olivier , Dalmais Éléonore , Ledésert Mariannick , Trullenque Ghislain , Sengelen Xavier , Genter Albert
Published: June 2021

The Soultz-Sous-Forêts geothermal site (France) operates three deep wells for electricity production. During operation, scales precipitate within the surface installation as (Ba, Sr) sulfate and (Pb, As, Sb) sulfide types. Scales have an impact on lowering energy production and inducing specific waste management issues. Thus scaling needs to be reduced for which a thorough characterization of the scales has to be performed. The geothermal brine is produced at 160 °C and reinjected at 70 °C during normal operation. In the frame of the H2020 MEET project, a small heat exchanger was tested in order to allow higher energy production, by reinjecting the geothermal fluid at 40 °C. Samples of scales were analyzed by XRD and SEM-EDS, highlighting that mostly galena precipitates and shows various crystal shapes. These shapes can be related to the turbulence of the flow and the speed of crystal growth. Where the flow is turbulent (entrance, water box, exit), crystals grow quickly and mainly show dendritic shape. In the tubes, where the flow is laminar, crystals grow more slowly and some of them are characterized by well-developed faces leading to cubes and derived shapes. The major consequence of the temperature decrease is the increased scaling phenomenon.
Assessment of Postpartum Depression in Adolescents Who Delivered during COVID-19 Social Restrictions: The Experience of a Tertiary Hospital from Bucharest, Romania
Authors: Matei Alexandra , Dimitriu Mihai Cornel Traian , Cirstoveanu Catalin Gabriel , Socea Bogdan , Ionescu Cringu Antoniu
Published: June 2021

In the context of the viral spread of COVID-19 in 2020, Romanian authorities declared national confinement for two months. Our country faces a public health issue regarding adolescent pregnancy. This study assessed the predisposition of teenage mothers to postpartum depression and the influence of the viral pandemic on their emotional status. This study enrolled patients 10 to 19 years old who delivered in our department between March–December 2020. Teenagers were attributed to the “lockdown group” (n = 30) and the “open group” (n = 171). All study participants agreed to take an interview based on a three-part questionnaire, including the Edinburgh Postnatal Depression Scale (EPDS). In the “lockdown group”, 16.67% of patients felt stressed over the last year compared to 11.11% of individuals in the “open group”, but there was no statistically significant difference between groups regarding overall EPDS scores (z value 0.51, Mann–Whitney U test). Predictable variables for postpartum depression were the use of cigarettes (OR = 1.08, 95% CI: 1.00–1.16), intended pregnancies (OR = 0.25, 95% CI: 0.09–0.68, p = 0.007) and absence of stressors in the last year (OR = 0.07, 95% CI: 0.02–0.30, p = 0.0002). More adolescents were stressed during confinement compared to those who delivered in the following time period; this aspect did not interfere with depression screening scores. A planned pregnancy, even during adolescence, can serve as a protective factor for postpartum depression.