bluuebunny/crossref_metadata_2025 huggingface dataset:
IN SILICO ANALYSIS OF TARGET GENES AND DESIGNING OF sgRNA FOR CRISPR
CONTROL OF CLINICAL METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS
Authors: Chandran Preethi , Gopal Shubha
Published: July 2023

Background: Methicillin-resistant Staphylococcus aureus (MRSA) infections pose considerable death and disability among individuals in both community and hospital-associated settings. This is substantial, as MRSA is often resistant to several types of antibiotics and is challenging to treat. Clustered regularly interspaced short palindromic repeats (CRISPR)- CRISPR - associated protein 9 (Cas9) gene editing system is one of the potential and promising strategies for controlling MRSA infections by specically targeting conserved gene sequences. The study aims Objective: to identify the potential target gene sequence and design sgRNA for the CRISPR Cas9 system to intercept clinical Methicillin-resistant Staphylococcus aureus (MRSA). Bioinformatic analysis of potential target genes Methodology: such as accessory gene regulator (agr A), staphylococcal protein A (spa), and antibiotic methicillin resistance gene mec A was performed to identify the conserved region. Spacers for the target were designed using an online bioinformatic tool for the construction of sg RNA. Result: The conserved sequence of the genes agrA, spa, and mec A of MRSA was chosen as a target for the study. Using the in silico method CHOPCHOP, spacers for each target gene were designed for genome editing to construct CRISPR- based antimicrobial gene knockout modules. In this Conclusion: study, we explored the possible potential target genes agrA, spa, and mecA in MRSA and tools for the construction of the sgRNA for the development of CRISPR based antimicrobial module against MRSA
Rhetoric and Political Power: Analyzing Language and Persuasion in Political Discourse
Authors: Isa Sulaiman Muhammad , Zayyad Kudu Muhammad
Published: July 2023

This abstract presents a research paper that examines the pragmatic influence of rhetorical strategies in political speeches. The paper acknowledges that language manipulation by politicians can result in threats and hate speeches, posing a challenge to peace, unity, and progress. The theoretical framework used is Fairclough's Model and Analytical Framework, and the methodology employed is qualitative research. The data for the study were collected from print media advertisements in Nigerian newspapers during the period of political campaigning for the March 2015 general elections. The data primarily consist of campaign speeches delivered at rallies by politicians from the Peoples' Democratic Party (PDP) and All Progressives Congress (APC). Content analysis is used to analyze the data in line with the research framework. The study emphasizes the contextual nature of rhetoric, highlighting the importance of the speaker-audience relationship within the broader sociopolitical context. The conclusion suggests that rhetorical strategy is a significant aspect of political analysis and can contribute to understanding the operation of political power in society.
Nason Al’adu Cikin Adabi: Nazarin Abincin Hausawa Na Gargajiya A Rubutattun Waƙoƙin Hausa
Authors: Qadeer Muhammad Abdul-
Published: July 2023

Hausawa suna da abincinsu na gargajiya iri daban-daban da suka gada daga iyaye da kakanni, waɗanda suka riƙe a matsayin cimakarsu ta yau da kullum. Babban muradin wannan muƙala shi ne, ta fito da yadda ire-iren abincin Hausawa na gargajiya ya yi naso cikin rubutattun waƙoƙin Hausan. An ɗora aikin ne a kan ra’in nason al’adu a cikin adabi. Bugaggun littattafai da kundayen bincike da mujallu da muƙalu da fasahar sadarwa ta zamani suna daga cikin hanyoyin da aka yi amfani da su wajen tattara bayanai na wannan bincike. A waƙoƙin da aka nazarta, an gano ire-iren abincin Hausawa na gargajiya iri daba-daban har guda hamsin da tara da suka yi naso cikin rubutattun waƙoƙin da aka yi nazarta.
Soil macrofauna correlations with soil chemical and physical properties and crop sequences under no-tillage
Authors: Batista Itaynara , Machado Deivid Lopes , Correia Maria Elizabeth Fernandes , Spinelli Maria Helena Moraes , Corá José Eduardo
Published: July 2023

Soil macrofauna is an important indicator of soil quality, as it is sensitive to changes in the environment as a result of soil management, which includes soil chemical and physical properties and the diversity of cultivated species. This study aimed to evaluate the composition and structure of soil macrofauna under a no-tillage system in different crop sequences, with and without crop rotation, over two growing seasons: a rainy summer and a dry winter. The crop sequences were soybean/corn rotation in the summer and corn in the winter; soybean/corn rotation in the summer and sunn hemp in the winter; soybean monoculture in the summer and sunn hemp in the winter; and corn monoculture in the summer and corn monoculture in the winter growing season. The nutrient content of the crop residues left on the soil surface, soil chemical and physical properties, and soil macrofauna were determined. Functional plant groups (grasses or legumes) individually influenced the composition of soil macrofauna more significantly than the effect of crop sequence, with or without rotation, and growing season. Grasses favored an increased density of groups such as Oligochaeta, Isoptera, and Formicidae. In contrast, legumes contributed to the variation in the total density of individuals and Diplura and Coleoptera groups. Furthermore, the influence of functional plant groups (grasses or legumes) on the composition and density of soil macrofauna were related to soil chemical (P and N content) and physical properties (particulate organic carbon and soil moisture), which determined the composition of soil macrofauna groups.
Safety and effectiveness of selective internal radiation therapy with SIR-Spheres Y-90 resin microspheres for treatment of hepatocellular carcinoma: A prospective observational study
Authors: Trong Khoa Mai , Hong Bang Mai , Pham Minh Thong , Dang Luu Vu , Hai Binh Tran , Trinh Chau Ha , Tien Thinh Nguyen , Doan Ky Thai , Van Thai Pham , Duy Anh Nguyen , Cam Phuong Pham
Published: July 2023

The study aimed to evaluate the safety and effectiveness of selective internal radiation therapy (SIRT) in patients with unresectable hepatocellular carcinoma (HCC) in Vietnam. A single-arm, multicenter, prospective observational study on the use of SIRT in patients with HCC was conducted with 6 months of patient follow-up. At baseline, eligible patients had Eastern Cooperative Oncology Group (ECOG) status ≤1, total bilirubin ≤2 mg/dL, tumor burden ≤50%, Child-Pugh score A or ≤B7, and Barcelona Clinic Liver Cancer stage A – C. Patients with extrahepatic disease, signs of liver failure, or previous external beam radiation to the liver were excluded. Primary outcomes were tumor response according to modified Response Evaluation Criteria in Solid Tumors criteria, changes in liver function, and adverse events (AEs) assessed using Common Terminology for AEs v4.03 and the investigators’ clinical judgment. The secondary outcome was the percentage of patients alive at 6 months. Two centers enrolled 30 patients (median age 60 years) in 2017 and 2018. All patients were Child-Pugh A; among them, 28 were ECOG 0. Most had hepatitis B (n = 17, 57%) or D (n = 10, 33%). Target lesion response at 6 months was 23% complete response, 37% partial response, 7% stable disease, and 7% progressive disease. Of the 8 patients (27%) not evaluated, 2 had become eligible for resection, 2 had contraindications to imaging, and 4 were lost to follow-up. Laboratory values, including α-fetoprotein, did not change significantly from baseline to 6 months. The most common AEs were abdominal pain (37%) and vomiting (17%). Nine episodes of abdominal pain in 6 patients were treatment-related. Serious AEs included progressive cirrhosis (n = 1) and progression of HCC (n = 5). All patients were alive at 6 months. In conclusion, the safety and clinical effectiveness of SIRT were confirmed in patients with unresectable HCC in Vietnam.
Personality traits in homosexual men with different sex roles in Iran
Authors: Pourmohseni Shakib Seyed Mohsen , Rezaei Sajjad , Naseh Ashkan
Published: July 2023

Studies on homosexual men reveal a secondary self-label, the sex role, which can affect many dimensions of their lives. Based on their roles in anal intercourse, homosexual men adopt self-label or sex role as top, bottom, and versatile. Unwelcoming social space, along with the legal and religious constraints in Islamic communities on homosexuality has made information about their personality traits scarce. Therefore, this study assessed the personality traits of homosexual men with different sex roles and compared them to each other and heterosexual men. In an ex post facto study, 197 Iranian homosexual men (30 tops, 36 bottoms, and 131 versatile) and 49 Iranian heterosexual men were included using purposive and snowball samplings to complete a short 71-item Minnesota Multiphasic Personality Inventory-2 (MMPI-2). The results showed top group obtaining highest mean score among the groups for scales of validity (F) and hypochondriasis (Hs), while bottom group obtaining highest mean scores for scales correction (K), depression (D), hysteria (Hy), paranoia (Pa), psychasthenia (Pt), and hypomania (Ma). These results suggested that bottoms encounter more difficulties in forming relationships and concealing their sexual identity. Depression, hopelessness, and a sense of failure in attracting support and affection from others are more prominent among bottoms.
Epidural Anaesthesia Technique in Caesarean Section Operation in Pregnant Patients with Rheumatic Heart Disease and Severe Mitral Stenosis
Authors: Wangsa Aditya , FX Adinda Putra Pradhana  , Tjahya Aryasa EM  , Cynthia Dewi Sinardja
Published: July 2023

Introduction: Mitral stenosis (MS) is the most common form of rheumatic heart disease (RHD). Pregnant women with moderate/severe MS are more prone to heart failure and pulmonary edema than normal pregnant women. It is very important to prevent the potential for maternal heart failure before delivery. This study aimed to present a case report on the epidural anaesthesia technique in caesarean section in pregnant patients with rheumatic heart disease and severe mitral stenosis.

Case presentation:  A 31-year-old pregnant woman patient came to the hospital with complaints of shortness of breath and found rheumatic heart disease and severe mitral stenosis. The patient was premedicated with fentanyl 50 mcg and midazolam 1 mg intravenously, followed by oxygen supplementation with a 2 lpm nasal cannula. Anaesthesia was performed using a lumbar epidural technique, with the insertion of an epidural catheter in the L1-L2 intervertebral space, targeting the T10-L1 dermatome and T6-L1 target of the viscerotome. The local anaesthesia agent chosen was plain bupivacaine with a concentration of 0.5% and a volume of 25 ml. The onset of action of epidural anaesthesia is achieved within 15 minutes as long as the operation is reached a total blockade as high as T6. During surgery, the patient is monitored with standard monitors and an artery line. There were no complaints of shortness of breath felt by the patient during the operation.

Conclusion: Epidural anaesthesia technique can be performed safely in pregnant women with comorbid mitral regurgitation and atrial fibrillation, with good intraoperative hemodynamic stability.
ДИТИНА В ЧАСИ БІДИ І НАДІЇ. ПОДОЛАННЯ ЛИХА ВІЙНИ, ЕПІДЕМІЙ, СОЦІАЛЬНИХ, ПСИХОЛОГІЧНИХ І ФІЗИЧНИХ ВАД У ДІТЕЙ ТА МОЛОДІ: МІЖНАРОДНА КОНФЕРЕНЦІЯ
Authors: Berezivska Larysa
Published: July 2023

Представлено мету та результати участі в роботі Міжнародної конференції «Дитина в часи біди і надії. Подолання лиха війни, епідемій, соціальних, психологічних і фізичних вад у дітей та молоді», що відбулася в Чехії 19-20 червня 2023 р. Захід організовано Національним педагогічним музеєм та бібліотекою Я.А. Коменського, факультетом мистецтв Карлового університету в Празі, Інститутом історії Чеської академії наук (Центр історії освіти), Технічним університетом Ліберця, Цюріхським і Дрезденським університетами. Розкрито особливості проведення, напрями роботи міжнародної конференції з актуальної проблеми історії освіти — історії дитинства у різні історичні періоди. Поінформовано про ключові доповіді учасників конференції із 14 країн світу (Бельгія, Італія, Німеччина, Словаччина, Україна, Чехія та ін.), присвячені історії подолання криз в освіті, спричинених пандеміями, війнами, тоталітарними режимами тощо. Аргументовано актуальність європейської інтеграції задля подолання соціальних, економічних, культурних і екологічних криз, що загрожують психологічному, фізичному, соціальному та моральному здоров’ю дітей і молоді.
Implementation of Facebook Marketplace for Convection and Embroidery UMKM Products (Jack Convection Medan) as an Effort to Increase Online Marketing and Sales
Authors: Aisyah Siti , Hutasuhut Muhammad Anshari
Published: July 2023

This research is entitled Implementation of Facebook Marketplace for Convection and Embroidery UMKM Products (Jack Convection Medan) as an Effort to Increase Online Marketing and Sales. The purpose of this research is to promote library services at the Muhammadiyah University of North Sumatra. The aim of the research is to find out that social media (Facebook) can provide convenience for MSME actors, especially for convection and embroidery business people. This study uses a descriptive qualitative research method. Marketing and sales of MSME products are currently carried out by participating in various MSME product exhibitions organized by the government and business actors who provide exhibition facilities, broadcast messages, and wait for customers to arrive at the store. This way of disseminating information is not effective because it does not reach people who live far from museums or retail locations that hold exhibitions. Facebook has a marketplace feature that allows promotions and sales to be unlimited by space and time, making it one of the social media platforms that is currently widely used and in demand by MSME players. By utilizing the Facebook marketplace, MSME can more easily market their products and make sales via smartphones, which will help them increase their sales growth. The results of this research are expected to be input for MSME actors who are pioneering or who are already successful, namely how to promote their products via Facebook in this modern era so that their products are widely accessible to many people. .
Effect of Managerial Ownership and Gender Diversity on Directors on Tax Avoidance with Audit Quality as a Moderation Variable
Authors: Harahap Ruth Bae Eliani , Masripah Masripah
Published: July 2023

This research was conducted to ascertain and analyze the effect of managerial ownership and gender diversity on directors on tax avoidance with audit quality as moderation. This study also adds two control variables, namely profitability and firm size. The samples in this study used mining companies listed on the Indonesia Stock Exchange (IDX) for the 2019-2021 period and were sorted using the purposive sampling method so that 75 samples were obtained. By using multiple linear regression tests, the results of managerial ownership and gender diversity in directors have no effect on tax avoidance. Then audit quality strengthens the effect of managerial ownership on tax avoidance, and audit quality weakens the effect of gender diversity on directors on tax avoidance.
Influence Of Satisfaction, Commitment, And Trust Customer To Customer Loyalty Gojek Users In Bandar Lampung
Authors: Sanakri Kiky
Published: July 2023

In this modern era, people have various activities and to fulfill the needs of these activities, people need transfers as fork equipment or auxiliary equipment in carrying out their activities. One of the online transfer services currently available among the public is Gojek Indonesia, which is an online transfer service application that can be used on smartphones. To offer compliance to its customers, currently the services offered by Gojek range from a service system for accompanying passengers using motorized transportation, a food delivery service system, to a one day grocery shopping service system. The aim of this research is to identify the effects of Happiness, Commitment and Confidence in Compliance on Gojek consumers in Bos Lampung. The research used is quantitative research and the sampling method used in this research is probability sampling. The number of examples obtained was 81 respondents, namely Gojek clients in Bos Lampung. Based on the research results, it shows that satisfaction and trust elasticities have an impact on Gojek client compliance in Bos Lampung, while for elastic commitments it has no effect on Gojek client compliance in Bos Lampung. In this research the elastic effects of Satisfaction, Commitment and Confidence affect 78% of Gojek client compliance in Bos Lampung. Conversely, more than 22% is influenced by other aspects not monitored in this research.
Rancang Bangun Prototipe Loss Daya Listrik Bersakala Rumah Tangga Berbasis Arduino ESP8266
Authors: Ance Azis Steven , Tansa Salmawaty , Nasibu Iskandar Z , Abdussamad Syahrir , Dako Amirudin Y.
Published: July 2023

Maraknya pencurian listrik rumah tangga yang terjadi saat ini sangat merugikan pihak PLN (Perusahaan Listrik Negara)  karena praktek curang yang dilakukan untuk mendapatkan biaya beban listrik yang rendah. Oleh karena itu, penggunaan piranti atau alat yang dapat digunakan sebagai prototype rancangan pendeteksi penggunaan listrik dari pihak PLN sangat dibutuhkan. Sehingga permasalahan yang terkait dengan pencurian listrik dapat dideteksi, dikarena pasokan listrik yang tidak stabil bisa menggangu peralatan rumah tangga. Penelitian ini bertujuan untuk merancang alat yang dapat memonitoring selisi daya yang disuplay PLN dan daya yang terpakai pada konsumen. Perancangan alat ini menggunakan sensor PZEM004T yang berfungsi untuk mengukur nilai tegangan, arus dan daya dari  listrik AC serta  pengontrolannya menggunakan Arduino ESP 8266 sebagai perangkat pendukungnya dikarenakan sistem ini berkerja pada perangkat keras dan perangkat lunak yang saling terkait antara keduanya. Aplikasi Blynk digunakan sebagai platform untuk menampilkan daya yang dikirimkan oleh sensor PZEM004T. Hasil pengujian yang dilakukan terhadap hasil pengukuran sensor dan dibandingkan dengan alat ukur yang telah terstandarisasi mendapatkan nilai keakuratan sebesar 1,732%The rise of household electricity theft that is happening at this time is very detrimental to the PLN (State Electricity Company) because of fraudulent practices carried out to get low electricity costs. Therefore, the use of a device or tool that can be used as a prototype design for detecting electricity usage from the PLN is urgently needed. So that problems related to electricity theft can be detected, because an unstable electricity supply can disrupt household appliances. This study aims to design a tool that can monitor the difference in power supplied by PLN and the power used by consumers. The design of this tool uses the PZEM004T sensor which functions to measure the value of voltage, current and power from AC power and controls it using the Arduino ESP 8266 as a supporting device because this system works on hardware and software that are interrelated between the two. The Blynk application is used as a platform to display the power delivered by the PZEM004T sensor. The results of tests carried out on sensor measurement results and compared with standardized measuring instruments get an accuracy value of 1.732%
Different Molecular Phenotypes of Progression in BRAF- and RAS-Like Papillary Thyroid Carcinoma
Authors: Lim Jinsun , Lee Han Sai , Park Jiyun , Kim Kyung-Soo , Kim Soo-Kyung , Cho Yong-Wook , Song Young Shin
Published: July 2023

Background: Papillary thyroid carcinoma (PTC) can be classified into two distinct molecular subtypes, BRAF-like (BL) and RASlike (RL). However, the molecular characteristics of each subtype according to clinicopathological factors have not yet been determined. We aimed to investigate the gene signatures and tumor microenvironment according to clinicopathological factors, and to identify the mechanism of progression in BL-PTCs and RL-PTCs.Methods: We analyzed RNA sequencing data and corresponding clinicopathological information of 503 patients with PTC from The Cancer Genome Atlas database. We performed differentially expressed gene (DEG), Gene Ontology, and molecular pathway enrichment analyses according to clinicopathological factors in each molecular subtype. EcoTyper and CIBERSORTx were used to deconvolve the tumor cell types and their surrounding microenvironment.Results: Even for the same clinicopathological factors, overlapping DEGs between the two molecular subtypes were uncommon, indicating that BL-PTCs and RL-PTCs have different progression mechanisms. Genes related to the extracellular matrix were commonly upregulated in BL-PTCs with aggressive clinicopathological factors, such as old age (≥55 years), presence of extrathyroidal extension, lymph node metastasis, advanced tumor-node-metastasis (TNM) stage, and high metastasis-age-completeness of resection- invasion-size (MACIS) scores (≥6). Furthermore, in the deconvolution analysis of tumor microenvironment, cancer-associated fibroblasts were significantly enriched. In contrast, in RL-PTCs, downregulation of immune response and immunoglobulin-related genes was significantly associated with aggressive characteristics, even after adjusting for thyroiditis status.Conclusion: The molecular phenotypes of cancer progression differed between BL-PTC and RL-PTC. In particular, extracellular matrix and cancer-associated fibroblasts, which constitute the tumor microenvironment, would play an important role in the progression of BL-PTC that accounts for the majority of advanced PTCs.
CGScholar and How It Interfaces With Mobile Devices
Authors: Sletten Michael A.
Published: July 2023

CGScholar is a learning platform that is cutting-edge in how it allows users to access it and how users can interact within it. Mobile devices are becoming the device of choice when it comes to accessing content on the internet due to their ubiquitous nature and compact size. How the user sees the content in CGScholar depends on which device they choose to access it with, as screen size of the mobile device and how that content is rendered on the screen depends on the device choice. Another major consideration is security which must be taken into account at the mobile device level, CGScholar, web browser, wireless networks, and computer networks. Security is of high concern in a mobile learning environment such as CGScholar because the nature of the data being stored and exchanged can possibly be protected under FERPA and/or PII regulations.
A batina como projeto de família
Authors: Burity Luiz Mário Dantas
Published: July 2023

Na última década do século XIX, a família de José Américo tomou providências quanto à sua escolarização. Ao observarem a tradição familiar de formar padres poderosos no estado e a aparente vocação do rapaz para o mundo das letras, decidiram encaminhá-lo para a vida sacerdotal. O objetivo deste texto é compreender como o projeto do sacerdócio foi arquitetado e vivido pela família e pelo próprio José Américo. Com esse propósito, as reflexões de Pierre Bourdieu (2004) e Lev Vigotski (2009) foram agenciadas e foram consultados livros de memórias, processos de ordenação e os registros de exames do seminário. Percebeu-se que o garoto experimentou a formação sacerdotal, primeiro, entre as vivências na casa de seu tio padre, depois de modo institucionalizado no seminário. Por vezes, tomou as lições como violências ao seu corpo e às suas ideias, mas, em outras, se identificou com o que aprendia, atingindo boas notas nos exames
Надання першої медичної допомоги при пораненнях великих судин кінцівок в умовах бойових дій. Турнікетний синдром та його профілактика
Authors: Samarskyi I. M. , Khoroshun Е. М.
Published: July 2023

Метою дослідження була оцінка поточної практики застосування кровоспинних турнікетів в умовах широкомасштабного російського вторгнення.

Матеріал та методи. Проаналізовані результати госпіталізацій поранених у кінцівки під час бойових дій російсько-української війни (2014-2022), в тому числі дані щодо типу накладених турнікетів, клінічний перебіг поранення в  залежності від тривалості накладання турнікету, клінічні висліди після реконструктивних втручань, кількість ампутацій, функціональний стан кінцівок впродовж 24 місячного періоду катамнестичного спостереження. Додатково проведений аналіз клінічних наслідків 12 випадків, коли турнікет знаходився на ураженій кінцівці більше ніж 6 годин. Статистична обробка проведена методами частотного та дисперсійного аналізу із застосуванням програмного забезпечення Statistica 13.0 (TIBCO, США).

Результати. За період активних бойових дій до медичних підрозділів Південного оперативного командування надійшло 2496 хворих із пораненнями кінцівок, які потребували накладання турнікетів. Встановлено структуру поранення у кінцівки в залежності від кількості накладених турнікетів  Термін знаходження турнікета на кінцівці коливався від 50 до 380 хвилин.  У 92 (3,7%)  випадках були виконані ампутації кінцівок. Кількість летальних випадків склала 101 (4,0%) випадків. За час активних бойових дій ми зіткнулися з 11 випадками тяжкого турнікетного синдрому, у 9 (81,8%) випадках вдалося врятувати кінцівку.  Основною причиною ампутацій після тривалого знаходження турнікету була наявність обширних некрозів.

Висновки. При коректному накладанні турнікету час його знаходження на кінцівці не має перевищувати двох годин. За період активних бойових дій до медичних підрозділів Південного оперативного командування надійшло майже 2,5 тисяч хворих із пораненнями кінцівок, які потребували накладання турнікетів. Найбільш часто спостерігалися поранення нижніх кінцівок  – 84,4%. Відповідно, ураження верхніх кінцівок зустрічалися у 15,6%.  Як правило, поранений мав один накладений турнікет –61,6%, два турнікети було – 21,4%, три турнікети – у 17,0% випадках. Термін знаходження турнікета на кінцівці коливався в середньому  205,9±8,1 хвилин, тобто у значної кількості випадків мала місце тривала ішемізація тканин.Дотримання правил використання кровоспинного турнікету дозволяє уникнути виникнення турнікетного синдрома. Своєчасне виконання вимог сучасної тактичної медицини щодо тріажу та евакуаційного забезпечення дозволяє в деяких випадках зберегти уражену кінцівку, навіть коли термін накладання турнікету перевищує регламентний.
Management of the Financial Potential of Innovative Development of the National Economy in the Context of Digital Transformation
Authors: Lomachynska Iryna
Published: July 2023

"The relevance of the study is conditioned by the need to find ways to improve the financing management of innovative development of Ukraine in the conditions of global digitalisation. The purpose of the study is to analyse the financial support for innovative economic development in the context of digitalisation, identify problems, and develop proposals for its improvement. The methodological approach is based on: analysis of statistical information; comparison; graphical method; generalisation. The main results of the study should be considered: identification of the relationship between the volume of expenditures of industrial enterprises on innovation activities and the dynamics of innovation implementation; analysis and selection of the most significant sources of financing for innovative development of industrial enterprises; identification of the positive impact of informatisation on the introduction of innovations in the economy and improving the well-being of the population; substantiation of the need to increase state financial support for innovative activities of enterprises with the advantage of those innovative ideas that are the most cost-effective and aimed at the use of information and digital technologies, and the innovative product meets the requirements of environmental friendliness and provides for its use in the most necessary ways during the war period, in particular: machine-building, energy, agricultural, defence."
Analysis of the Impact of the War on the Economic State of Agriculture in Ukraine
Authors: Rexhepi Burhan Reshat
Published: July 2023

"The purpose of the study is to determine the impact of the war in Ukraine on the state of agriculture and the economy of the country in general. The general scientific and special methods were used to achieve the goal: synchronous and diachronic, logical, analysis and synthesis, dialectical, scientific abstraction, and comparative analysis. As a result, it was identified that the economy of Ukraine largely depends on agricultural production, but because of the war, the agricultural sector suffers huge losses. The indicators of total exports of Ukraine have almost halved in comparison with the pre-war period, agricultural land and uncollected crop become half of the entire structure of damage in agriculture, and due to constant hostilities, it is impossible to purchase feed and provide veterinary services to farm animals, as a result of which they die. In addition, the difficult economic state of agricultural production is also associated with a decrease in agricultural productivity, violation of crop cultivation technologies, recoupment of territories, lack of funds and human resources, and constant military operations, as a result of which the agricultural infrastructure has experienced unprecedented destruction. These reasons affect the internal and foreign markets, which is of great importance in ensuring world food security."
Implementasi Electronic Traffic Law Enforcement (Etle) Dalam Mendukung Terwujudnya Road Safety Policing (Studi Kasus Polda Banten)
Authors: Pardede Charles Rio Valentine
Published: July 2023

Tujuan dari penelitian ini adalah Menganalisis Implementasi Kebijakan program ETLE dan menganalisis faktor-faktor yang mempengaruhi implementasi program ETLE dalam mendukung terwujudnya Road Safety Policing di wilayah hukum Polres Serang Kota. Metode penelitian yang digunakan adalah menggunakan metode kualitatif deskriptif.  Keamanan, keselamatan, ketertiban, kelancaran lalu lintas (Kamseltibcarlantas) merupakan tujuan yang diinginkan setiap pengguna jalan. Perilaku pengguna jalan sangat berpengaruh terhadap terwujud atau tidaknya Kamseltibcarlantas.  Kehadiran E-Tilang di Kota Serang ini sebetulnya mampu untuk memberikan pengaruh kepada masyarakat untuk semakin meningkatkan kesadaran hukum akan tertib lalu lintas. Akan tetapi, dalam praktik di lapangan masih belum dilaksanakan secara maksimal dikarenakan kendala-kendala yang dihadapinya.
Crowd Violence Handling: Case Study Of Magelang City District Police
Authors: Setyawan Nugroho Ari
Published: July 2023

Kekerasan massa membahayakan kehidupan manusia dan memiliki kedekatan dengan masalah terkait kejahatan. Penelitian ini membahas tentang penanganan kekerasan massa di Polres Kota Magelang. Penelitian partisipatif, penelitian tindakan, dan analisis dokumen diterapkan untuk mengungkap fenomena tersebut. Anak-anak muda dipandang sebagai peserta massa yang dominan yang berimplikasi pada bagaimana polisi harus mempertimbangkan kembali pendekatan pemolisian mereka. Kerjasama dengan pihak-pihak terkait sangat diperlukan untuk mengupayakan remaja yang lebih taat hukum. Selain itu, strategi pencegahan kekerasan massa di tingkat Polres perlu disusun dan ditinjau secara berkala untuk menemukan metode yang lebih baik dan tepat. Oleh karena itu, kekerasan massa dapat dikurangi dan dicegah untuk keuntungan masyarakat yang lebih luas.
Evaluasi Distribusi BBM di Lingkungan Polri Dalam Mendukung Pelaksanaan Tugas Operasional Kepolisian Guna Mewujudkan Penguatan Pengawasan
Authors: Raslin Harvin
Published: July 2023

Penelitian ini diharap dapat menjadi informasi tentang evaluasi distribusi BBM di lingkungan Polri dalam mendukung pelaksanaan tugas operasional guna mewujudkan penguatan pengawasan. Tujuan dari penelitian ini untuk mengidentifikasi dan menganalisis pelaksanaan sistem perencanaan dan pengadaan BBM di lingkungan Polri, pelaksanaan distribusi BBM, dan sistem pengawasan distribusi BBM saat ini, serta merumuskan tata kelola BBM yang tepat di lingkungan Polri. Penelitian ini menggunakan metode campuran antara metode kuantitatif yang didukung dengan metode kualitatif. Responden menjawab kuesioner melalui handphone secara online. Selanjutnya, data kualitatif yaitu berupa narasi yang mendeskripsikan suatu realitas atau keadaan tertentu dari ruang lingkup penelitian. Pengumpulan data kualitatif dilakukan dengan cara FGD dengan peserta yang terdiri dari pejabat utama dan anggota Polri yang menjadi responden. Dalam pendistribusian BBM, masih terdapat beberapa kendala seperti kesamaan dokumen perencanaan dari tahun sebelumnya dan sertifikasi personel yang minim. Diharapkan tata Kelola pendistribusian ke depannya dapat lebih efektif dan efisien dan pengalihan penggunaan bentuk kertas pada Ranjen dan kupon menjadi kartu digital.
Evaluasi Kualitas Dan Penggunaan Pdh Polisi Tidak Berseragam Dan Pakaian Dinas Khusus Pegawai Negeri Pada Polri
Authors: Raslin Harvin
Published: July 2023

Penelitian Evaluasi ini diharapkan diperoleh data, fakta dan informasi tentang kualitas dan penggunaan PDH Polisi tidak berseragam dan PDK Pegawai Negeri pada Polri sehingga dapat diberikan rekomendasi perbaikan penggunaan PDH dan PDK tersebut.  Metode penelitian ini menggunakan metode campuran (mix methode), yaitu gabungan antara metode kuantitatif yang didukung dengan metode kualitatif.  Pengumpulan data kualitatif dilakukan dengan cara wawancara mendalam dengan informan yang terdiri dari pejabat utama dan anggota Polri di 10 (sepuluh) Polda dan 34 (tiga puluh empat) Polres Jajaran sebagai sampel. Total responden dalam penelitian ini sebanyak 1953 orang. Hasil dari evaluasi menunjukkan  kualitas PDH Polisi tidak berseragam telah memiliki beberapa aspek yang sudah memuaskan, namun masih dijumpai   pakaian terasa panas,  gerah jika dipakai dan tidak menyerap keringat, ukuran dan jahitan tidak sesuai postur badan anggota.   Pengawasan dilakukan oleh PJU Polda dan pengemban fungsi Logistik. Polres belum maksimal dilibatkan baik dalam perencanaan, pengadaan dan pengawasan. Penggunaan PDH Polisi tidak berseragam dampaknya sangat positif, antara lain meningkatkan rasa soliditas dan rasa kekeluargaan, menumbuhkan kebanggaan, motivasi dan humanis serta sikap profesional anggota  dalam bertugas.
Die Geschichte der Chemie an der Ludwig-Maximilians-Universität München
Authors: Wolfgang Beck
Published: July 2023

Contemporary documentation of the chemistry department at the Munich Ludwig Maximilians University, a world center of modern chemistry. With 70 short biographies of professors who worked there.
ANALISIS KEMAMPUAN GURU DALAM MENINGKATKAN MOTIVASI BELAJAR SISWA PADA PEMBELAJARAN PKN SDN X BATUSANGKAR
Authors: Yulita Anggina , Safrizal  , Sunarti
Published: July 2023

In an effort to boost the learning motivation of high school elementary school students, the teacher's efforts to leave this learning open at the end of the PKN semester. Understanding and improving student learning outcomes in PKN learning can be supplemented by increasing learning motivation. The aim of this study was to identify teacher tools to increase the learning motivation of high school elementary students during PKN classes. This study uses a qualitative case study methodology. The method used to gather information for this study is called objective sampling. In this research instrument, the researchers themselves collected data using observation techniques, questionnaires, and document analysis. Data analysis techniques use data collection, editorial, display, and conclusion steps. The guarantor of the validity of the data in this third study combines the method of collecting data by combining triangulation. The results of the study indicated the need for greater motivation to teach high grade students during Internship classes. One of the factors that causes students' learning motivation to be lower than it should be is their exposure to less than ideal learning environments and less than ideal teaching methods. Therefore the advice given by the teacher to increase student learning motivation is to use teaching strategies that can do this. This includes offering counselling services and using ice-breaker activities such as games and ice hockey.
PEMBUATAN SABUN CAIR ANTISEPTIK DARI KOMBINASI VIRGIN COCONUT OIL (VCO) DAN TEH HIJAU (Camellia Sinensis) INFUSED OIL
Authors: Annita  , Niken  , Yusuf Rahmi Novita
Published: July 2023

The use of synthetic materials as active ingredients in soap making has a negative effect on human skin such as causing irritation. These potential hazards can be overcome by making soap using natural ingredients as activeingredients such as VCO and green tea. The purpose of this activity is to provide socialization to the community in the Pasir Jambak Coast of Padang regarding Hand Washing with Soap (CTPS). In technical implementation, thecommunity service team made liquid soap followed by education about CTPS and the distribution of free liquid soap to the community. The implementation methods and approaches developed in the PKM program activities can overcome the mindset about the importance of washing hands. The result of this service is that the community is enthusiastic in participating in counseling and understanding the importance of CTPS.
UPAYA PENINGKATAN PENGETAHUAN DAN KETERAMPILAN WALI SISWA TAMAN KANAK-KANAK (TK) DI BANYUMAS DALAM PENANGANAN PENYAKIT INFEKSI SALURAN PERNAPASAN AKUT (ISPA)
Authors: Nur Histiyani Rani Afifah , Handini Tri Okmawati , Afifah
Published: July 2023

Acute respiratory tract infection (ARI) is one of the infectious disease that is the main cause of morbidity and mortality in the world. ARI is the main cause of infant and under-five mortality. Parents knowledge and skills play an important role in handling ARI in toddlers. The purpose of this community service is to increase the knowledge and skills of parents about acute respiratory infections (ARI) in children and how to handle them. Community service is carried out in August-September 2020 with the target of guardians of the Aisyiyah Bustanul Atfal Kindegarten students in Banyumas. The methods used is interactive lectures and discussions to increase knowledge, while to improve skills by simulating cases in small groups. The knowledge of Kindegarten parents in dealing with ARI has increased, as evidenced by the increased in the questionnaire scores, from 77.5 to 90.8. Guardian skills improve after case simulation
PENINGKATAN PENGETAHUAN SKABIES PADA ANAK USIA SEKOLAH DI KELURAHAN KERAMASAN, KERTAPATI, PALEMBANG
Authors: Erwin Edyansyah  , Karneli  , Nurhayati
Published: July 2023

Keberadaan skabies dapat dipengaruhi oleh faktor umur yang paling sering menginfeksi pada anak-anak dibandingkan dengan dewasa, karena daya tahan tubuh yang lebih rendah dari orang dewasa, kurang menjaga kebersihan, dan lebih seringnya mereka bermain bersama anak-anak lain dengan kontak yang erat. Penyuluhan Skabies merupakan kegiatan pengabdian kepada masyarakat dalam rangka memberikan edukasi kesehatan serta meningkatkan kualitas kesehatan masyarakat. Waktu pelaksanaan pengabdian masyarakat adalah bulan April 2023. Tempat pelaksanaan pengabdian kepada masyarakat adalah di Sungai Pedado Kelurahan Keramasan Kertapati. Kegiatan dilaksanakan secara luring di lokasi dengan melakukan tatap muka. Sasaran dalam pengabdian masyarakat ini adalah anak usia sekolah yang berada di lokasi kegiatan pengabdian masyarakat. hasil pengetahuan tentang Skabies sebelum dilakukan penyuluhan dan edukasi hasil pre-test baik didapatkan hasil lebih rendah yaitu berjumlah 12 (40%) anak daripada pre-test kurang berjumlah 18 (60%) anak. Post-test dilakukan setelah penyuluhan dan edukasi tentang Skabies terjadi peningkatan jumlah pengetahuan tentang Skabies post-test baik lebih banyak yaitu berjumlah 22 (73%) anak dibandingkan dengan post-test kurang yang berjumlah 8 (27%) anak. Dari kegiatan pengabdian kepada masyarakat ini dapat disimpulkan yaitu: Kegiatan penyuluhan pengetahuan anak usia sekolah mengalami peningkatan dari hasil pre-test dan post-test.
EDUKASI POLA MAKAN SEHAT DI HARI RAYA DAN PEMANFAATAN TERAPI KOMPLEMENTER
Authors: Rahmayanti Rini , Fitria Alisa  , Viki Yusri  , Lenni Sastra
Published: July 2023

Penyakit tidak menular (PTM) merupakan masalah kesehatan yang menjadi penyebab kematian di dunia. Peningkatan PTM juga terjadi di Provinsi Sumatera Barat. Dua PTM yang menjadi perhatian Dinkes Sumbar adalah hipertensi, dengan jumlah kasus 43.319 orang, Diabetes Melitus (DM) 28.704 kasus dan penyakit jantung sebanyak 25.465 kasus. Cara paling penting untuk mengurangi kematian akibat PTM adalah dengan mengubah gaya hidup yang tidak sehat. Pola makan yang sehat selama hari raya perlu diketahui masyarakat agar terhindar dari gejala PTM. Metode edukasi yang dapat diberikan adalah dengan media leaflet dan pembagian takjil sehat berupa salad buah. Tujuan kegiatan ini adalah meningkatkaan pengetahuan masyarakat tentang pola makan sehat dsadn pemanfaatkan terapi komplementer berupa terapi herbal. Kegiatan ini terlaksana di Kelurahan Surau Gadang dengan jumlah sasaran 60 orang dewasa termasuk ibu hamil dan ibu menyusui. Masyakat sangat antusias dengan kegiatan ini. Diharapkan adanya edukasi berkelanjutkan dari Puskesmas setempat khususnya mengenai pola hidup masyarakatzaman seakrang ini agar terhidar dari penyakit tidak menular.
GAMBARAN KESEHATAN MENTAL REMAJA
Authors: Wetik Syenshie Virgini , Laka Angela Maria Alfonsin Lusia
Published: July 2023

Masalah kesehatan mental yang umumnya dialami remaja adalah cemas, depresi, perasaan takut, agresif, hiperaktifitas, menarik diri, konflik dengan teman sebaya dan lingkungan sosial. Apabila tidak teratasi maka berdampak pada konfilik internal yaitu malu, murung, mudah menangis atau marah, memberontak, merasa tidak bahagia, tidak berharga/rendah diri dan juga berdampak secara fisik misalnya gangguan tidur, lelah, mudah gelisah, tegang, perilaku bullying serta memikirkan keinginan untuk mengakhiri hidup. Tujuan penelitian untuk mengetahui gambaran kesehatan mental remaja. Jenis penelitian deskriptif kuantitatif dengan metode total sampling berjumlah 144 responden. Penelitian dilakukan pada bulan Maret 2023 di SMKN 6 Manado. Instrumen yang digunakan adalah strength and difficulties questionnaire (SDQ). Analisis yang digunakan adalah survei deskriptif cross-sectional. Hasil penelitian menunjukkan 61,1% berada pada kategori abnormal untuk skor gejala perilaku, 45,8% berada pada kategori normal untuk skor masalah perilaku, 75,7% berada pada kategori normal untuk skor hiperaktifitas, 52,1% berada pada kategori borderline untuk skor masalah teman sebaya dan 86,8% berada pada kategori abnormal untuk skor kesulitan. Sedangkan untuk skor kekuatan/perilaku prososial yang mendeteksi masalah kesehatan mental 88,2% berada pada kategori normal. Hasil penelitian ini dapat menjadi masukan bagi pengembangan ilmu dan intervensi keperawatan dalam bidang kesehatan jiwa baik program preventif dan promotif dengan melibatkan peran aktif dari keluarga, teman sebaya, sekolah dan masyarakat di lingkungan sosial.
FAKTOR – FAKTOR YANG BERHUBUNGAN DENGAN PELAKSANAAN ORAL HYGIENE PADA PASIEN STROKE DI RUANG RAWAT INAP DEWASA RSUD DR. (H.C.) IR. SOEKARNO PROVINSI BANGKA BELITUNG
Authors: Melisa Melisa , Anggraini Rima Berti , Agustiani Sirli
Published: July 2023

Stroke merupakan gangguan fungsional otak akut lokal maupun global karena terhambatnya aliran darah ke otak akibat pendarahan ataupun sumbatan dengan gejala sesuai dengan bagian otak yang terkena, yang sembuh sempurna, cacat, atau kematian. Oral hygiene (kebersihan mulut) adalah sebuah usaha untuk menjaga kebersihan rongga mulut, lidah, dan gigi dari berbagai macam kotoran atau sisa makanan dengan menggunakan air bersih (Budi, 2017). Data pasien stroke pada tahun 2019 jumlah pasien stroke sebanyak 101 pasien (11,82%), pada tahun 2020 jumlah pasien stroke sebanyak 136 pasien (15,92%) dan pada tahun 2021 jumlah pasien stroke sebanyak 144 pasien (16,86%). Tujuan penelitian ini faktor – faktor yang berhubungan dengan pelaksanaan oral hygiene pada pasien stroke di ruang rawat inap dewasa RSUD Dr. (H.C.) Ir. Soekarno Provinsi Bangka Belitung Tahun 2022. Penelitian ini menggunakan desain cross sectional, menganalisa dengan uji chi square. Populasi adalah semua semua perawat rawat inap dewasa. Pengambilan sampel menggunakan cluster sampling, dengan jumlah sampel sebanyak 89 sampel. Penelitian ini menyimpulkan bahwa faktor – faktor yang berhubungan dengan pelaksanaan oral hygiene pada pasien stroke di ruang rawat inap dewasa RSUD Dr. (H.C.) Ir. Soekarno Provinsi Bangka Belitung Tahun 2022 adalah pendidikan (p=0,014), pengetahuan (p=0,002), beban kerja (p=0,041), lama kerja (p=0,018) dan faktor paling dominan berhubungan dengan pelaksanaan oral hygiene pada pasien stroke di ruang rawat inap dewasa adalah pengetahuan (p=0,002, dan POR=4,667). Disarankan kepada petugas kesehatan agar meningkatkan pengetahuan dan tanggungjawab perawat terhadap pelaksanaan oral hygiene pada pasien yang mengalami penurunan kesadaran dan meningkatkan kesadaran perawat dalam pelaksanaan di lapangan.
Биометрические данные: новые возможности и риски
Authors: Карцан И. Н.
Published: July 2023

Рассматриваются вопросы защиты персональных данных при использовании биометрических технологий, так как независимо от того, сканируется ли кончик пальца, лицо или радужная оболочка глаза, собираемая информация является персональной информацией об идентифицируемом человеке. Проанализированы новые возможности биометрии и ее применение в различных сферах жизни, таких как финансы, медицина, безопасность и др., наиболее распространенным примером биометрических данных является фотография, используемая в паспорте, водительском удостоверении или медицинской карте. Проще говоря, изображение лица человека фиксируется и сохраняется, чтобы впоследствии сравнить его с другой фотографией или с живым человеком. Также статья охватывает риски, связанные с использованием биометрических данных, такие как возможность их утечки, фальсификации и злоупотребления не только при централизованном механизме доступа на различные объекты, но и на каждом отдельном объекте доступа. Представлены методы защиты биометрических данных, такие как шифрование и использование мультифакторной или двухфакторной аутентификации. Даны рекомендации по защите личной информации и контролю за ее использованием при развертывании любой технологии или услуги, использующей биометрические данные.
HEALTH EDUCATION WITH A FOCUS ON CARE FOR CHRONIC DISEASES
Authors: Do Monte Massela Malta Arlete , Rodrigues Alexsandro , Zanatelli Carla , Moraes Gabriela , De Matia Graciele , Cristine da Silva Suellen , Cicero da Silva Luciano
Published: July 2023

This intervention xchang is xchang the work management and education and health research line and will seek to raise the awareness of patients with chronic diseases to adopt healthy habits, such as good nutrition, regular physical exercise practices and periodic exams to measure glycemic indexes , blood pressure, among others, through lectures, information, whether physical (pamphlets and posters) or digital (communication channels on social networks such as Whatsapp, for the exchange of information between patients and health professionals, aiming to increase well-being and quality of life as well as promoting education for the prevention of these diseases through informative actions and interventions in the population assisted in health establishments and schools.