bluuebunny/crossref_metadata_2025 huggingface dataset:
Focal tetanus involving both thoracic limbs successfully treated with magnesium sulfate in a dog
Authors: Royaux E. , Plessas I. N. , Smith P.
Published: September 2020

A six-year-old, male, neutered Cocker spaniel was referred for a three-week history of progressive thoracic limb stiffness. The dog became non-ambulatory due to severe thoracic limb stiffness, which was exacerbated by external stimuli. The pelvic limbs appeared to be normal. Based on the history and the physical examination, a presumptive diagnosis of focal tetanus of the thoracic limbs was made. The dog was treated supportively with tetanus antitoxin, antimicrobials, sedation and muscle relaxants; however, this treatment did not control the muscle spasms adequately. Magnesium sulphate was added to alleviate the muscle spasms and to reduce the sedation requirements. The dog improved and was discharged after three weeks of intensive treatment.
The application of the Global Competence Matrix in a virtual exchange program with US and Brazilian students
Authors: Salomão Ana Cristina Biondo , Viana da Silva Eduardo
Published: September 2020

This paper presents the details of a virtual exchange project conducted with 14 university students from Brazil and 14 university students from the US during the US spring quarter of 2019. This virtual exchange was part of the Teletandem Brasil Project, which has been developed by São Paulo State University (UNESP) in Brazil and aims at promoting cultural and language learning in tandem. Students watched videos about current topics in Brazil and in the US and discussed them with their international partners. After the mediation sessions, the participants analyzed the results of their conversations through the Global Competence Matrix, a set of guidelines created by the US global competence task force in 2011. The results point to the importance of using an educational tool to promote a deeper cultural understanding, which in this paper focused on the issue of feminism in Brazil and in the US.
Kapasitas Kelembagaan Pengelola Desa Wisata Brajan Kabupaten Sleman
Authors: Paskasari Clara Shinta
Published: September 2020

Tourism is a rapidly growing sector in Indonesia in recent years. Tourism development is now also moving to villages by raising local wisdom in each place. Brajan is one of the Tourism Villages in Sleman Regency which is included in the growing category. This village is interesting to share because it has great potential and offers a more varied compared to supported villages. One indicator in determining village classification is in terms of capacity of its managers. For this reason, a study was conducted to see the capacity of managers in Brajan to take part in the strategies taken to improve it.The study was conducted qualitatively with data collection methods in the form of interviews, observation, and documentation. Informants in the interview were managers of tourist villages, youth, and the community. The aim is to mapping institutional capacity. Organizational capacity will be seen from managerial aspects, resource management, and participation.The results of this study indicate that managerial does not have the ability to manage programs and processes, but in terms of relationship management and collaboration is good. In terms of managing resources, both human resources and infrastructure, financial and technological resources are still lacking. Participation is still lacking because many managers are already inactive.
Wujud Adaptasi Masyarakat Kalibiru dalam Pengembangan Ekowisata
Authors: Kaharuddin Kaharuddin
Published: September 2020

Ecotourism development by local communities around the forest has obstacles related the differences between farming and tourism working style. The problem's related the ability of the community to adapt. This study is aimed to describe the types of obstacles, strategies and the form of adaptation of the Kalibiru community in developing ecotourism in the protected forest. Data collection uses in-depth interviews (indept interview), focused interviews, direct observation, and document review. The results showed the ability of the Kalibiru community to adapt of ecotourism. Various obstacles experienced at each stage of tourism development can be overcome through persuasive strategies. The adaptation can be seen in the changes individual behavior, the structure and rules of the HKm institution, and settings of labor and working time at the household level. Keywords. Adaptation, ecotourism, local communities
DEVELOPMENT AND VALIDATION OF STABILITY-INDICATING RP-UPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF TEZACAFTOR AND IVACAFTOR IN FORMULATIONS
Authors: MANEKA S. LAKSHMI , SARAVANAKUMAR R. T. , ANJANA C. H. K. V. L. S. N.
Published: September 2020

Objective: Aim of the present research work was to develop a sensitive, rapid and accurate, stability-indicating RP-UPLC method for the simultaneous estimation of tezacaftor and ivacaftor in formulations.

Methods: The chromatographic separation of the mixture of tezacaftor and ivacaftor was attained in isocratic method utilizing a mobile phase of 0.1 % orthophosphoric acid and acetonitrile in the proportion of 50:50%v/v utilizing a HSS C18 column which has dimensions of 100×2.1 mm, 1.7 m particle size and the flow rate of 0.3 ml/min. The detection system was monitored at 292 nm wavelength maximum with 1.5 ml injection volume. The present method was validated as per the guidelines given by the ICH for specificity, accuracy, sensitivity, linearity and precision.

Results: The retaining time for tezacaftor and ivacaftor were achieved at 1.071 min and 0.530 min, respectively. Tezacaftor, ivacaftor and their combined drug formulation were exposed to thermal, acidic, oxidative, photolytic, and alkaline conditions. The developed method was highly sensitive, rapid, precise and accurate than the earlier reported methods. The total run time was decreased to 2.0 min; hence, the technique was more precise and economical. Stability studies directed for the suitability of the technique for degradation studies of tezacaftor and ivacaftor.

Conclusion: The projected method can be utilized for routine analysis in the quality control department in pharmaceutical trades.
MOLECULAR DOCKING OF SELECTED BIOACTIVE COMPOUNDS FROM AZADIRACHTA INDICA FOR THE INHIBITION OF COVID19 PROTEASE
Authors: SHARON S. FEBINA BERNICE
Published: September 2020

Objective: COVID-19 caused by novel SARS-coronavirus 2 belonging to family Coronaviridae, is a global public health emergency infecting many people all around the world, especially in India with more than 2,98,000 cases. Hence there is a need for a novel drug that counters SARS-CoV2 is the prime requirement at this time.

Methods: The present study aimed to assess bioactive compounds found in Azadirachta indica as a potential inhibitor of COVID-19 Mpr °(6Y2E, 6LU7, and 2GTB) by Autodock 4.2, with the Lamarckian Genetic Algorithm. COVID-19 Mpr ° was docked with thirteen bioactive compounds, and docking was analyzed by Autodock 4.2 and Pymol. Nelfinavir and Saquinavir were used as positive standards for comparison.

Results: Azadirachtanin, Azadirachtol, and Salannolide, were left out because of the violation of Lipinski’s rule. The binding energies obtained from the docking of 6Y2E with a native ligand, Azadiradione, Beta-sitosterol, Epiazadiradione, Epoxyazadiradione, Kaempferol, Meldenin, Myricetin, Nimbaflavone, Nimbinene, Nimbione, Nimbocinolide, Quercitrin, Vepnin, Saquinavir, and Nelfinavir were-7.32,-6.63,-6.69,-7.52,-5.27,-4.54,-6.07,-4.19,-5.02,-5.58,-6.23,-4.71, -3.72,-6.4,-7.14 and-4.67 kcal/mol respectively. The binding energies obtained from the docking of 6LU7 with the native ligand, Azadiradione, Nimbione, Vepnin, and Saquinavir were-6.14,-6.48,-6.79 and-6.49 kcal/mol correspondingly. The binding energies obtained from the docking of 2GTB with the native ligand, Azadiradione, Epiazadiradione, Epoxyazadiradione, Kaempferol, Meldenin, Myricetin, Nimbaflavone, Nimbione, Nimbocinolide, Quercitrin, Vepnin, Saquinavir, and Nelfinavir were-6.96,-7.13,-6.69,-5.22,-6.44,-5.06,-5.93,-6.66,-5.3,-5.63,-7.11,-6.89 and-5.42kcal/mol, respectively.

Conclusion: Azadiradione, Epiazadiradione, Nimbione, and Vepnin seemed to have the greatest potential to act as COVID-19 protease inhibitors. However, further research is necessary to explore their prospective medicinal use in vitro and in vivo conditions.
Effect of ascorbic acid on chemical content and viability of cocoa seed after storage
Authors: Sekewael Willy Daniel , Pudjihartati Endang , Santoso Teguh Iman
Published: September 2020

Storage of oily seeds will make the seeds deteriorated, this caused by auto-oxidation. It will changes the biochemical and physiology of the seeds. Application of Antioxidant can prevent the activity of auto-oxidation. This research aimed to study the effect of ascorbic acid to minimize the deterioration by observing the chemical content and viability of Theobroma cacao L. seeds. It was conducted at kaliwining experimental station, Indonesia Coffee and Cocoa Research Institute, Jember, East Java and at Universitas Kristen Satya Wacana, Salatiga, Central Java. The research used Completely Randomized Design and T-test analysis. The treatments consisted of  four ascorbic acid concentrations, i.e. 0 ppm as control, 250 ppm, 300 ppm, and 350 ppm. The treated cacao seeds were stored on two shelf life i.e. 1 week and 2 weeks. Each treatment was repeated with seven replications. Data analysis used SAS 9.0. The results showed that ascorbic acid application can effect on reducing sugar, protein, lipid, free fatty acid content, and viability of cocoa seeds. Ascorbic acid with concentration of 250 ppm and 300 ppm can maintain cocoa seeds viability until 2 weeks of shelf life.
Performance of Biochemical Compounds and Cup Quality of Arabica Coffee as Influenced by Genotype and Growing Altitude
Authors: Nugroho Dwi , Basunanda Panjisakti , Yusianto Yusianto
Published: September 2020

Arabica coffee (Coffea arabica) cultivation in the medium altitude (700-900 m above sea level, asl.) will face problems such as decreasing productivity, physical, biochemical and cup quality and increasing intensity of pest and diseaseattacks. Utilization of plant material that has good productivity and cup quality, resistance to pests and diseases is an effort that can be done to overcome theseproblems. The aims of this study is to evaluate performance of Arabica coffee quality grown at high and medium altitude area, as well as biochemical compound and cup quality changes that occur due to influence of genotypes and genotype × altitude interactions. Eight genotypes of Arabica coffee were evaluated at two locations namely KP Andungsari (1,250 m asl.) and Kalibendo (700 m asl.). The field design for each location was randomized complete block design with three replicates. Observations were made on the two quality aspects, namely the biochemical compounds and cup qualities. The result on the biochemical compounds showed that the altitude significantly affect to the content of caffeine, sucrose, and trigonelline. Effect of genotype × altitude occured to the caffeine, trigonelline, and sucrose content. Diversity of chlorogenic acid content was caused by the genotype effect. Cup test results showed that genotypes grown at high altitude had a better cup quality than genotypes on medium altitude. Cup quality variables that were changed due to altitude difference were fragrance and aroma, flavor, aftertaste, acidity, balance, and overall, while the cup quality variable that did not changed was the body. Characters of coffee aroma at the high altitude were floral, spicy and fruity, while at the medium altitude were herbal, green and grassy. The best quality genotype at the high altitude was K8, while at the medium altitude was K29. Environment (altitude) gives greater influence to the formation of coffee flavor variations produced compared to genotypes.
Potential and Stability of Promising Fine Flavor Cocoa Clones in Different Seasons:
Authors: Anitasari Indah , Setyawan Bayu , Soesilo Agung Wahyu
Published: September 2020

The intensity of vascular streak dieback (VSD) disease is one of the major causes of decreased fine flavor cocoa production in Indonesia; therefore, it is essentialto develop superior planting materials resistant to this disease. The purpose of the study was to conduct initial identification of yield potential and resistancelevel to VSD disease in several promising clones of fine flavor cocoa and to identify bean quality profile. This study was conducted at Kaliwining Experimental Station, Indonesian Coffee and Cocoa Research Institute, Jember, Indonesia, with an altitude of 45 m above sea level (asl.) and C climate type, according to the Schmidt-Ferguson classification system. The study design used a complete randomized block design consisting of 13 promising clones and 3 superior clones of fine flavor cocoa as control. Each treatment was repeated 4 times in blocks, and each plot consisted of 5 plants. The results showed that PNT 16 was potential to be developed as a superior promising clone of fine flavor cocoa with high yield potential (66.6 pods/ tree/year equal to 2.52 kg dry bean/tree/year) and low VSD level (VSD score: 0.4) in first year of production (4 years old after planting). The superior promising clone of PNT 16 comprises of 35.1 beans per pod with good quality, weighed by 1.25 g/bean, and a higher percentage of white seeds above 80% (94.9%). Furthermore, the specifications of the main flavor attributes are similar to ICCRI 09 and dominated by the browned roasted, nutty and browned fruit aroma. Therefore, the clone has the potential to be developed as one of the special cocoa products.
Moradia adequada: um direito sobressalente como vital em tempos de Covid-19
Authors: Nascimento Marilza Ferreira do
Published: September 2020

O presente artigo versa sobre a mora dos poderes públicos concernente à efetivação do direito fundamental à moradia para milhões de brasileiros e o agravamento das consequências da falta de habitação adequada em decorrência do surto pandêmico da Covid-19. Apresentam-se, inicialmente, alguns aspectos gerais interpretativos das cláusulas constitucionais garantidoras desse direito. A seguir, faz-se a comparação de dados sobre a Covid-19 e as condições habitacionais para demonstrar que o direito à moradia adequada se correlaciona diretamente com o direito à saúde e à vida. Conclui-se, ao final, pela inconstitucionalidade dos instrumentos de planejamento dos gastos públicos quando estes forem omissos em alocar recursos para se fazer fronte às prestações materiais, por intermédio das quais o direito à moradia adequada se realiza.
Novo coronavírus e racismo ambiental: favelas brasileiras como zonas de necropolítica
Authors: Júnior Gilson Santiago Macedo , Carvalho Claudio Oliveira de
Published: September 2020

Embora se diga que o novo coronavírus (SARS-CoV-2) é um vírus democrático, atingindo ricos e pobres, buscamos demonstrar neste artigo que a pandemia se alastra e é combatida de formas diferentes, tendo em consideração aspectos de classe e de raça, o que, no movimento por justiça ambiental, recebe o nome de racismo ambiental. Tomando por paradigma a construção de favelas brasileiras e o modo como o Poder Público reage nessas localidades, é possível concluir que há operação necropolítica no combate à covid-19, isolando as favelas enquanto zonas de necropolítica.
A pandemia Covid-19 como pedagogia neoliberalizante no Brasil
Authors: Werner Deborah , Rocha Clarice
Published: September 2020

O advento da Covid-19 evidencia a relevância do Estado enquanto agente primordial para o enfrentamento da crise econômica e sanitária instaurada pelos efeitos da pandemia, assegurando condições mínimas necessárias de consumo e bem-estar durante o período de isolamento social, perspectiva contraditória ao papel atribuído ao Estado ao longo do processo de neoliberalização em curso no Brasil desde a década de 1990. A despeito disso, as políticas públicas para a contenção do vírus revelam a prevalência das prerrogativas neoliberais, aspectos analisados à luz da implementação do Auxílio Emergencial, por meio da Lei n° 13.982 de 2020, que confere uma renda básica emergencial às famílias de baixa renda.
A pandemia de Covid-19: aspectos do seu impacto na sociedade globalizada do século XXI
Authors: Macedo Luziene Dantas de , Macedo José Roberval Dantas de
Published: September 2020

O ponto de partida deste trabalho é realizar uma discussão sobre a pandemia de Covid-19 e aspectos do seu impacto na sociedade globalizada do século XXI. A ideia é refletir sobre os desafios para vencer a doença, um claro problema social, mas negligenciado pelas políticas neoliberais, em que pese a importância do papel do Estado, da valorização do sistema de saúde pública, das políticas de assistência social, do socorro aos pequenos negócios, entre outras questões. A dominação e o controle do espaço, da natureza física e da vida humana e animal do planeta, expressões do capitalismo, e responsáveis pela destruição das bases que sustentam a relação harmoniosa entre o homem e o meio ambiente, estão sendo desafiadas por influências externas, no caso um vírus com potencial pandêmico, que impactou e deixou o motor da acumulação de capital particularmente vulnerável. Se o momento propicia pensarmos e sonharmos com um mundo melhor, mais justo e sustentável, ambiental, social e economicamente, a realidade sobrepõe os desafios que nos são impostos, como as desigualdades sociais e o desemprego. Assim, é urgente a construção de uma arquitetura político-institucional, uma forte cooperação intra e interpaíses e a valorização da vida de todos os seres (animais e vegetais) pertencentes ao planeta Terra.
The Role of Communication Mode in Auditor-Client Interactions: Insights from Staff Auditors
Authors: Carlisle Melissa , Hamilton Erin L.
Published: September 2020

Research suggests that staff auditors are more comfortable interacting with client personnel through email than face-to-face and that this choice of communication mode has the potential to impact audit outcomes. However, very little is known about how staff auditors choose a communication mode and its effects on their client interactions. Therefore, we present survey-based evidence that the majority of staff auditors prefer to interact with the client face-to-face but use face-to-face and email relatively equally. Auditors who primarily email the client place less value on client connection, and those who prefer email report feeling more communication anxieties related to the client. Importantly, the use of face-to-face communication is associated with more positive and productive client interactions. Firms can use the results of our study to understand the factors influencing staff auditors' preference for and use of different communication modes and its effect on audit outcomes, particularly as remote work increases.
Patrolling Monocytes Are Recruited and Activated by Diabetes to Protect Retinal Microvessels
Authors: Tecilazich Francesco , Phan Toan A. , Simeoni Fabio , Scotti Giulia Maria , Dagher Zeina , Lorenzi Mara
Published: September 2020

In diabetes there is a long latency between the onset of hyperglycemia and the appearance of structural microangiopathy. Because Ly6Clow patrolling monocytes (PMo) behave as housekeepers of the vasculature, we tested whether PMo protect microvessels against diabetes. We found that in wild-type mice, diabetes reduced PMo in the general circulation but increased by fourfold the absolute number of PMo adherent to retinal vessels (leukostasis). Conversely, in diabetic NR4A1−/− mice, a model of absence of PMo, there was no increase in leukostasis, and at 6 months of diabetes, the number of retinal acellular capillaries almost doubled compared with diabetic wild-type mice. Circulating PMo showed gene expression changes indicative of enhanced migratory, vasculoprotective, and housekeeping activities, as well as profound suppression of genes related to inflammation and apoptosis. Promigratory CXCR4 was no longer upregulated at longer duration when retinal acellular capillaries begin to increase. Thus, after a short diabetes duration, PMo are the cells preferentially recruited to the retinal vessels and protect vessels from diabetic damage. These observations support the need for reinterpretation of the functional meaning of leukostasis in diabetes and document within the natural history of diabetic retinopathy processes of protection and repair that can provide novel paradigms for prevention.
Patrolling monocytes are recruited and activated by diabetes to protect retinal microvessels
Authors: Admin Ada , Tecilazich Francesco , Phan Toan A. , Simeoni Fabio , Scotti Giulia Maria , Dagher Zeina , Lorenzi Mara
Published: September 2020

In diabetes there is a long latency between onset of
hyperglycemia and appearance of structural microangiopathy. Because Ly6Clow
patrolling monocytes (PMo) behave as housekeepers of the vasculature, we tested
whether PMo protect microvessels against diabetes.

We found that, in wild-type mice, diabetes
reduced PMo in the general circulation but increased by 4-fold the absolute
number of PMo adherent to retinal vessels (leukostasis). Conversely, in
diabetic NR4A1-/- mice ─ a
model of absence of PMo ─ there was no increase in leukostasis at all;
and at 6 months of diabetes the number
of retinal acellular capillaries almost doubled when compared to diabetic
wild-type mice. Circulating PMo showed gene expression changes indicative
of enhanced migratory, vasculo-protective, and housekeeping activities; as well
as profound suppression of genes related to inflammation and apoptosis.
Pro-migratory CXCR4 was no longer upregulated at longer duration, when retinal
acellular capillaries begin to increase.

Thus, after short diabetes duration, PMo are the cells
preferentially recruited to the retinal vessels and protect vessels from
diabetic damage. These observations support the need for reinterpretation
of the functional meaning of leukostasis in diabetes, and document within the
natural history of diabetic retinopathy processes of protection-repair that can
provide novel paradigms for prevention.
NON-DENSITY OF GENERIC M-REDUCIBILITY FOR C.E. SETS
Authors: Rybalov A. N.
Published: September 2020

Generic-case approach to algorithmic problems was suggested by I. Kapovich, A. Myasnikov, V. Shpilrain and P. Schupp in 2003. This approach studies behavior of an al-gorithm on typical (almost all) inputs and ignores the rest of inputs. C. Jockusch and P. Schupp in 2012 began the study of generic computability in the context of classical computability theory. In particular, they defined a generic analog of Turing reducibility. A. Rybalov in 2018 introduced a generic analog of classical m-reducibility. In this paper we study the generic m-reducibility for c.e. sets and prove that unlike classical m-reducibility, generic m-reducibility does not have the density property for c.e. sets.
The Nagorno-Karabakh Conflict in the Context of Securitization Theory
Authors:   Southern Federal University, Konovalov Valery Nikolaevich , Poghosyan Gurgen Kajikovich
Published: September 2020

The paper analyzes the prospects for resolving the Nagorno-Karabakh conflict from the point of view of an explanatory model that reveals the logic of inter-national conflicts. This model is based on regional security complex theory developed in the framework of securitization theory by representatives of the Copenhagen School of security studies. The authors of the paper consider the basic operational elements of these theories and apply them to the analysis of the Nagorno-Karabakh conflict. It is concluded that the situation in Nagorno-Karabakh depends signifi-cantly on external actors. In this context, an im-portant point of research on the conflict is the elab-oration of conceptual principles that develop the analytical framework of securitization theory and regional security complex theory. Such an approach can contribute to ensuring stability and security in the South Caucasus.
Government Procurement: Challenges and Solutions to the Realities of the Pandemic
Authors:   Financial University under the Government  of the Russian Federation, Kochikin Ivan Vadimovich
Published: September 2020

The paper analyses the problems of procurement activities using budget funds and measures to solve them in the pandemic, and the subsequent period. Mechanisms for state regulation of procurement procedures during the implementation of sanitary and epidemiological measures aimed at protecting the population were considered. Timeliness of the solution: expanding the list of goods (works, ser-vices) for purchase from a single supplier, as a force majeure measure, gave rise to new corruption risks. An analysis of violations related to public procure-ment suggests that the existing system is generally cumbersome and not mobile. The way out: to standardize the legislation governing public pro-curement and to change the main indicator of pro-curement: the initial maximum price. This will serve as the basis for solving the problems of public pro-curement that exist and are identified by the pan-demic.
Duplication of Normative Text in Legal Acts: Theoretical Basics and Legal Significance
Authors:   Krasnodar University of the Ministry  of Internal Affairs of Russia, Uporov Ivan Vladimirovich
Published: September 2020

The present study considers the problem of duplica-tion of identical text in normative legal acts from the standpoint of legal legal engineering. Such legal phenomenon as copying legal norms without any reference to the act used takes place at all levels of a law-making process (federal, regional, municipal). It is regarded by the author as the defect of the men-tioned process, since a state of some uncertainty arises for the law enforcement officer, there is viola-tion of competence in subjects of regulation and, accordingly, the effectiveness of law as a social reg-ulator decreases. Theoretical and legal judgments are illustrated by specific examples from lawmaking activities of various public authorities. It is conclud-ed that the reproduction of a normative text, even with references, is generally impractical, but it is acceptable mainly in municipal legal acts. The study substantiates proposals on improving the infor-mation and technical state of the Russian legal sys-tem.
Problem Aspects of Qualification of Hiv Transmission
Authors:   Kuban State University, Kufleva Valentina Nikolayevna , Sobolev Daniil Vladimirovich ,   Kuban State University
Published: September 2020

The work discusses the study of technical and legal aspects of аrt. 122 of the Criminal Code of the Rus-sian Federation «HIV transmission», which deter-mine the problems of qualification of the crimes stipulated by it. The causes and conditions that prompted the legislator of the Russian Federation to recognize acts on the spread of HIV infection as socially dangerous and criminalize are investigated. A structural analysis of аrt. 122, focuses on contro-versial positions, causing a potential gap in the cur-rent legislation and leading to a discrepancy be-tween the norm of the Special Part and the provi-sions enshrined in the General Part of the Criminal Code of the Russian Federation. Practical and simu-lated hypothetical examples confirming the pres-ence of a problem are given. A number of possible amendments to the criminal law are presented, on the basis of which a new version of аrt. 122 of the Criminal Code is proposed. Based on the study, the corresponding conclusions are formulated.
The State Strategy of Counteraction to Extremism in Modern Russia
Authors:   Volgograd Institute of Management – branch  of Russian Presidential Academy  of National Economy and Public Administration, Morozov Ilya Leonidovich , Abramov Aleksandr Eduardovich ,   Volgograd Institute of Management – branch  of Russian Presidential Academy  of National Economy and Public Administration
Published: September 2020

On May 29, 2020, the amendments proposed by the Ministry of Internal Affairs of the Russian Federation to ”The Strategy of Counteraction to Extremism in the Russian Federation until 2025” came into force. The aim of the study is a political analysis of the main points of these amendments, assessment of their compliance with the nature of contemporary threats caused by activation of extremist organiza-tions and movements on the territory of modern Russia and the development of practical recommen-dations. Based on the set of tools of systematic and multifactorial approaches, the authors come to the conclusion that extremism as a political phenome-non is currently in the stage of intensifying its activi-ty, transforming the types of manifestation, which requires a prompt response from state structures. Despite the amendments to the Strategy that have entered into force, further work is needed to opti-mize it, in particular changes to paragraphs 4, 15 and 32 regarding terminology, migration policy, the staff training system for countering extremism.
Cross-Border Interaction as a Factor of Regional Security (on the Example of the Rostov Region)
Authors:   Southern Federal University, Konovalov Valery Nikolaevich , Martirosyan Sofia Ashotovna ,   Southern Federal University, Poghosyan Gurgen Kajikovich
Published: September 2020

The paper deals with the impact of the situation in the South-East of Ukraine on the security of the Rostov region, which has long borders with the Do-netsk and Luhansk regions. Contemporary studies of border regions imply a synthesis of traditional and postmodern methodologies. In this regard, the concepts of a transborder region and a transconflict region are used as the theoretical and methodologi-cal basis of this study. The authors analyze the cur-rent state and prospects of cross-border interaction, taking into account the features of the conflict zone of the Russian-Ukrainian border. It is concluded that it is necessary to minimize the consequences of the destructive potential of a number of negative pro-cesses and phenomena. The role of the Strategy for the Socio-Economic Development of the Rostov region is evaluated in terms of countering the chal-lenges and threats to regional security.
The Impact of Change of Power in Ukraine on the Possibility of Its European Integration
Authors:   Saint Petersburg State University, Gulyaev Egor Vladimirovich
Published: September 2020

The present study analyzes political changes that took place in Ukraine in 2019 and their impact on the integration of this country in the European Union (EU). The author considers the main criteria which every candidate for joining the EU is obligated to meet, the current circumstances which obstruct further rapprochement of Ukraine with the Western countries and the policy pursued by the new Ukrain-ian government aimed at bringing the mechanism of the government into line with the stated criteria. The conclusion made is that Ukraine does not have any significant achievements in the specified field due to the lack of staff to implement the reforms required to enter the EU as well as because of the processes taking place in the EU itself. However, the country still has the potential for progress in the future.
Corrosion Behavior Evaluation of TIG Welding Joint of Low Carbon Steel
Authors: Hussein A. Hussein
Published: September 2020

The current research studies the corrosion behavior of Low Carbon Steel 1020 AISI welded joint by means of TIG welding method using mutable DC current and constant voltage. Before the welding process, shot peening by steel balls for certain welded joints is applied to the sheet metal, and then welding under the same welding conditions without shot peening. A number of corrosion inspection samples have been prepared with the measurements of (15 * 15 * 3 mm), according to ASTM (G71-31). Microstructure, residual stress has been tested and the corrosion test has been conducted electrochemically in 3.5 per cent NaCl solution for all samples. Corrosion rate was computed by means of the Tafel equation. The results show a rise in corrosion rate in some welded joints compared with other welded joints and base metal due to the variation in heat input from the input current for each weld passes. Shot peening process contributed to lower corrosion rate compared to welded joints without shot peening, due to the residual compression stresses produced by shot peening process. The best results obtained when number of welds passes and welding current are decreased to get suitable heat input.
Analisis Kausalitas Stabilitas Perekonomian Terhadap Pengembangan Bank Syariah Menggunakan Pendekatan Vector Error Correction Model
Authors: Windarsari Wiwin Riski , S Zainuddin
Published: September 2020

Sektor keuangan memegang peran penting dalam mendorong perekonomian suatu negara. Sektor keuangan juga menjadi infrastruktur pendukung dalam memfasilitasi agar transaksi di sektor riil dapat dilakukan secara cepat, aman, dan efisien. Keseimbangan kedua sektor menjadikan ekonomi berjalan dengan sempurna. Keseimbangan ini secara simultan berimplikasi pada percepatan pembangunan dan peningkatan pertumbuhan ekonomi.Metode penelitian yang digunakan yaitu metode kuantitatif. Sumber data yang digunakan adalah data sekunder yang diperoleh dari Badan Pusat Statistik dan Otoritas Jasa Keuangan. Data diolah dan dianalisis menggunakan Vector Error Corection Model (VECM), menggunakan data dari bulan Oktober 2013 hingga September 2018. Variabel pada penelitian ini diantaranya  PDB, inflasi,  DPK, dan  PYD.Berdasarkan hasil penelitian ini diperoleh hubungan satu arah DPK terhadap PDB, dan IHK terhadap PYD, serta terdapat hubungan dua arah antara PDB dan PYD. Hal ini menandakan bahwa bank syariah berkontribusi dalam mendorong perekonomian negara dan pertumbuhan ekonomi berkontribusi dalam penyaluran pembiayaan
Analytical Spectrometric Study For Determining Dapagliflozin Propanediol Monohydrate Individually Or In Presence Of Metformin Hydrochloride In Tablets Formulation
Authors: SAAD ANTAKLI  , Raghad Kabbani  , And Rama Labban
Published: September 2020

First simple spectrophotometric method was developed and applied to determine Dapagliflozin Propanediol  Monohydrate by Zero Spectrophotometry and First Derivative Spectrophotometric method for determining of Dapagliflozin Propanediol Monohydrate (DAPA) in the presence of Metformin Hydrochloride (MET). Zero spectrophotometric (ZS) was applied for the determination of (DAPA) at 223.5 nm. Linearity range was (2.61– 31.23) µg/mL. Regression analysis showed a good correlation coefficients R2 = 0.9989. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.569 µg/mL and 1.724 µg/mL, respectively. Derivative spectrophotometric (1DS) was applied for the determination of (DAPA) in the presence (MET). (DAPA) was determined at 233 nm (1D233).  Linearity ranges were (5.21 – 41.64) µg/mL for (DAPA). Regression analysis showed a good correlation coefficients R2 = 0.9994. The limit of detection (LOD) and limit of quantification (LOQ) were to be 0.732 µg/mL and 2.218 µg/mL for (DAPA). The proposed Zero spectrophotometry method was applied to analysis individual (DAPA), and the derivative (1D233) method was applied to analysis (DAPA) individually or with (MET) combination in Syrian trademark drugs.
The image of the opponent of technological innovation in Galley Slave by A.Asimov: modern interpretation
Authors: Ulanova A. E.
Published: September 2020

The image of Simon Ninheimer — the opponent of scientific and technological progress — is described by A. Azimov in the story «Galley Slave». It is used to develop the idea of resistance to mechanization, which is now finding increasingly supporters due to the increased influence of information and communication technologies in general and artificial intelligence and robotics in particular. The historical and conceptual foundations of neo-luddism are linked with modern trends calling for a gradual, controlled innovation. It is noticed that the ideas of the luddites have been preserved in romantic literature and transformed into neo-luddism in the 20th century. The theorists of this movement use philosophical concepts of different epochs (e.g. Socrates, J.-J. Rousseau and M. Heidegger) to confirm the legitimacy of their own status. As a result, in the 21st century more moderate areas of struggle against scientific and technological progress are actively developing under the influence of postmodernism. For example, the slow movement is growing strength, and its supporters are trying to slow down the pace of life and are calling for a thoughtful, responsible attitude towards emerging technologies. The positions underlying the slow movement are in tune with the dromology of P. Virilio and the slow philosophy of G. Fleistad. However, neo-luddism has social status of counterculture, but the situation can be changed due to the rapid and sometimes uncontrollable development of technology.
Apgitir chrábaid in the context of an intertextual approach
Authors: Kiselev M. S.
Published: September 2020

This article is dedicated to methodological problems of intertextual relations studies which appear during the research of primary sources. The subject matter stands at the joint between several branches of knowledge: Religious studies, Cultural studies, Philology and Celtic studies. In this article, we make an attempt to find the most adequate methodological approach for the detection and description of intertextual relations. The source for our experiment would be an Irish primary source — Apgitir chrábaid, the earliest surviving Christian prose tract written in Old Irish. Moreover, the article contains a brief analysis of existing hypotheses which attempt to explain what exact Christian texts, written in Latin, influenced the structure and content of this treatise in particular: P.P. Ó Néill — John Cassian; T.O. Clancy and G. Márkus John Cassian and Basil the Great; A.A. Korolev — Isidore of Seville and John Cassian. Then we make critical remarks about the methodology of identification of said influences on Apgitir chrábaid chosen by those researchers and on the language of scientific description used by them. It is proposed to use methods developed within the theory of intertextuality as a more correct approach for marking and description of intertextual relations. The use of the intertextual description in working with primary sources is shown by the example of the analysis of the fragment from Apgitir chrábaid (§ 8). The result of the analysis is the hypothesis that the source of influence, the intertext, for the indicated fragment in addition to the text of the Holy Scripture, is the work «Homilies on Ezekiel» by Pope Gregory I the Great. As an additional argument in favor of this hypothesis, a brief review of the veneration of Pope Gregory I, recorded in Irish church literature, is given.
Public speaking skills in the traditional abkhaz society
Authors: Agrba L. A.
Published: September 2020

The article observes public speaking skills as a socio-cultural phenomenon in the traditional Abkhaz society at national and individual levels. The topicality of the study lies in analyzing certain functions and genre modifications of oratory tradition among Abkhazians. In our considered opinion, public speaking is an integral element of the life of Abkhaz people, an essential phenomenon for understanding the Abkhazian worldview, their culture and attitude to reality. Such analysis might be vital for the reconstruction of a holistic «portrait» of the Abkhazian ethnicity, understanding the character, intentions, mentality of its representatives. The aim of the study is to analyze the specific functions of oratory tradition for the Abkhaz society. The task is to classify its main functions; to consider genre modifications of oratory tradition aimed at harmonization of the society; to determine the role and importance of the speaker in the traditional Abkhaz society. On the basis of the research conducted, the author comes to the conclusion that in a traditional Abkhaz society is oratory performed a number of socially significant regulatory and ideological functions, namely, ordered intercultural interactions, coordinated the resolution of political and socially important issues, worked as a value-regulating mechanism. At an individual level, by mastering the art of speaking in public, Abkhazians realized natural social needs, the need for communication, socialization and creative activities.
Специализированные суда и развитие морской инфраструктуры Вьетнама
Authors:   Kulesh V., Pham Trung Hiep
Published: September 2020

Практика судоходства широко использует опыт посадки на грунт небольших судов, что очень важно для развития морской инфраструктуры Вьетнама. Отметим, что с увеличением размеров судов резко возрастают контактные нагрузки, следовательно, и вероятность повреждений корпусов. Ряд классификационных обществ учитывают это в части требований к проектированию. В настоящей
статье авторы предприняли попытку выполнить анализ особенностей таких судов (требования классификационных обществ, их недостатки) для последующего развития методик их проектирования и постройки. Для развития кораблестроения во Вьетнаме для нужд туризма необходимо учитывать
опыт других стран. Так, проведенное авторами статьи сравнение ветроволновых условий побережий
Вьетнама и России показало возможность и целесообразность учёта российского опыта. Рассмотрены
случаи повреждений корпусов при контактах судов с грунтом и ремонтов. Отмечена важная роль
внешней конструктивной защиты в повышении надёжности таких судов, и то, что ей не уделяется
достаточное внимание при проектировании.
Ключевые слова: посадка на грунт, повреждения, методики проектирования, внешняя конструктивная
защита, морская инфраструктура Вьетнама.

The practice of shipping makes extensive use of the experience of landing small vessels on the ground. This practice is very important for the development of Vietnam's marine infrastructure. As the size of vessels increases, contact loads and probability of damage to hulls increase as well. A number of classification societies consider and make this part of design requirements. In this article, the authors attempted to analyze the specifics of such vessels, to compare the requirements of classification societies, and to identify their shortcomings with a view to the subsequent development of design techniques. Vietnam's shipbuilding should also make good use of the other countries’ experience for further development of tourism and infrastructure. A comparison of the wind and wave conditions of the coasts of Vietnam and Russia showed the
capability and expediency of taking into account the Russian experience. Cases of damage to the vessel hulls at the contacts with the ground and repairs are considered. The important role of external structural protection in enhancing the reliability of such vessels, which does not receive enough attention, is noted.
Keywords: landing on the ground, damages, design techniques, external structural protection, Vietnam's maritime infrastructure.
The Changing Public Image of Nursing in Ghana
Authors: Appiah Evans Osei , Agyeiwaa Joyce , Amponsah Awuah
Published: September 2020

Several complaints have been lodged by the public on media regarding the attitudes of nurses in Ghana. Even though a few nurses are praised in the media, the negative complaints keep outweighing the positive reports. It has been observed that some nurses in Ghana are fond of sending student nurses to buy food and other items whilst on duty. The purpose of this article, therefore, is to discuss how nurses’ attitudes affect care positively and negatively and to improve the attitudes of nurses towards their patients during care. A situational analysis using a descriptive narrative approach is provided. The article is structured under five main headings, which are maintaining the personal hygiene of patients, respecting the dignity of patients, the dress of nurses in Ghana, selecting the right people for the profession, and inappropriate use of smartphones during work.
Nurse Managers’ Perspectives on Care Quality and Safety in Rural Hospitals in Uganda
Authors: Kakyo Tracy Alexis , Dongxia Xiao Lily
Published: September 2020

Rural hospitals in sub-Saharan African countries play a key role in dealing with a high level of disease burden, but are usually poorly equipped with resources. Ward nurse managers in rural hospitals are in an ideal position to negotiate resources and bridge gaps in quality improvements. The aim of this study was to explore nurse managers’ perspectives on quality and safe care in rural hospitals in Uganda. This was a qualitative interpretive study in which 11 ward nurse managers with at least two years’ experience in the role were purposively selected to participate in the study. In-depth interviews using a semi-structured interview guide were applied for data collection. Thematic analysis was applied to analyse the data. Four themes were identified from the interviews. These themes explained how nurse managers engaged stakeholders in quality and safe care for patients; supported staff through supervision; improvised practices to cope with resource and equipment constraints; and being constrained by poor working conditions. Nurse managers in rural hospitals in sub-Saharan Africa face unique challenges in ensuring quality and safe care for patients due to a lack of basic human and material resources. The strategies they apply in quality improvements have implications for policy and resource development.
Postcolonial Pragmatics: Changing lenses
Authors: Rocha Azevedo Dora Savoldi da
Published: September 2020

Seeking to account for the specificities of interactions in postcolonial societies contexts, Eric Anchimbe and Richard Janney (2010) developed the Postcolonial Pragmatics framework, which was the topic of Anchimbe’s homonymous lecture in Abralin ao vivo. As a result of colonization and the consequent mixture between indigenous and colonizers ways of life, postcolonial settings are marked by hybridized forms of concepts, language, social norms, and speech (e.g. code-mixing and code-switching), thus leading to communication strategies which have been shaped by these heterogeneous environments. Postcolonial Pragmatics consists of a framework based on an emic perspective which aims at taking into account the hybrid settings found in postcolonial societies in pragmatic analysis. Anchimbe presents us with a new theoretical lens through which phenomena drawn from these hybrid settings are considered central to the Pragmatics’ enterprise.
Associação entre a odontologia estética e autoestima
Authors: Oliveira Gabriella de Sá , Gusmão Yure Gonçalves , Nunes Flávio Marconiedson , Oliveira Isabela de Sá , Cangussu Lara Santos , Gonçalves Marcelo Cavalcanti
Published: September 2020

Este artigo teve como objetivo realizar análise sobre a associação entre o trabalho da odontologia estética e a autoestima dos pacientes. Para isso foi realizado estudo bibliométrico de publicações científicas sobre o assunto. A busca inicial das referências bibliográficas foi efetuada na Biblioteca Virtual de Saúde (BVS), de forma integrada, de maio a agosto de 2019. O estudo contou com a seleção final de 20 referências de 212 publicadas a partir do ano de 2007. Dessas 212 referências, 192 foram excluídas por não atenderem os critérios de inclusão propostos no protocolo da pesquisa.  De acordo com as referências, os fatores encontrados que impactam diretamente na autoestima dos indivíduos foram o edentulismo, amelogênese imperfeita, fluorose, dentes anteriores fraturados, diastema, sorriso gengival e posição inadequada da mandíbula. A deformidade dentofacial influencia não somente na autoconfiança, como também nos relacionamentos e qualidade de vida, resultando em impactos psicossociais. Todas as referências utilizadas neste estudo corroboram que a odontologia estética além de impactar no reestabelecimento da estética e função, atua na recuperação da autoestima. Desse modo, é de suma importância a preparação do profissional para que ele esteja apto a atender essa necessidade.