bluuebunny/crossref_metadata_2025 huggingface dataset:
KONSEP PENGEMBANGAN BISNIS ROTI BEKATUL DENGAN PENDEKATAN BUSINESS MODEL CANVAS PADA USAHA AYUSITA BAKERY KABUPATEN BERAU, KALIMANTAN TIMUR
Authors: Dhinar Anthonius , Syah Ranto , Irmawanti Anggun , Fadillah M. , Ayu Feriza
Published: November 2023

Indonesia sepenuhnya masih bergantung pada impor untuk memenuhi kebutuhan gandum sebagai bahan dasar roti. Jika keadaan ini dibiarkan, ketergantungan pangan dari luar negeri dapat meningkatkan pengeluaran devisa negara sehingga dikhawatirkan beberapa industri makanan berbasis tepung terigu akan mengalami ketergantungan. Untuk mengurangi kebutuhan tepung terigu pada pembuatan roti yaitu dengan mensubstitusi sebagian atau seluruh tepung terigu dengan tepung lain misalnya tepung bekatul. Roti dengan bahan dasar bekatul memiliki kandungan gizi yang tinggi sebagai bahan suplementasi dalam rangka pengkayaan gizi produk roti bekatul. Penelitian ini dilakukan untuk mengetahui perancangan model bisnis Ayusita Bakery dengan menggunakan metode Business Model Canvas dan melakukan analisis SWOT terhadap bisnis tersebut. Hasil menunjukkan bahwa Business Model Canvas dapat diterapkan dengan baik pada usaha ini dan berdasarkan analisis matriks SWOT yang telah dilakukan, maka dihasilkan alternatif atau pilihan strategi yang dapat diberikan untuk pengembangan usaha roti bekatul pada Ayusita Bakery
Expression of Angiopoietin-1 and the receptor Tie-2 mRNA in rat brains following intracerebral hemorrhage
Authors: Zhou HuaJun , Tang* Tao , Guo Canjie , Zhang Hainan , Zhong JianHua , Zheng Jie , Luo JieKun , Lin Yuan , Liu Wei , Luo WenFang , Yang QiDong
Published: November 2023

Angiopoietin-1 (Ang-1) belongs to a novel family of endothelial growth factors that function as ligands for an endothelialspecific receptor tyrosine kinase (Tie-2). The Ang-1/Tie-2 system may contribute to angiogenesis and vascular remodeling by mediating interactions of endothelial cells with smooth muscle cells and pericytes. The spatial distribution and temporal expression of Ang-1 and Tie-2 in the rat brain were studied following collagenase-induced intracerebral hemorrhage (ICH), by immunohistochemistry and reverse transcription-polymerase chain (RT-PCR) analysis, respectively. Immunohistochemical analysis revealed that some Ang-1 or Tie-2-positive dilated vessels resided around the hematoma and extended into the clot. RT-PCR analysis showed that Ang-1 and Tie-2 mRNA signal was detected at 2 days and persisted for 28 days after ICH. These findings suggest that ICH could lead to upregulation of Ang-1 and the receptor Tie-2 mRNA.
Sphingosylphosphorylcholine induces mitochondria-mediated apoptosis in neuro 2a cells: Involvement of protein kinase C
Authors: Miguel Begoña , Fernández Inmaculada , Toboso Inmaculada , Agudo-López Alba , Catalán Edgardo , Martínez Ana
Published: November 2023

We demonstrate that sphingosylphosphory1choline-mediated cell death involves the activation of different protein kinase C isozymes in different manners. Treating cells with sphingosylphosphorylcholine resulted in activation of protein kinase C delta, which is necessary, together with elevation of Ca2+, for sphingosylphosphorylcholine-induced apoptosis. A rapid translocation from cytosol to membrane, and a proteolytic protein kinase C delta cleavage was found, probably due to activation of caspase-3, to give a catalytically active fragment involved in cellular apoptosis. Moreover, sphingosyl­phosphory1choline also induced translocation of protein kinase C zeta, resulting in an anti-apoptotic effect. To explore whether a mitochondrial pathway is involved in sphingosylphosphorylcholine-induced apoptosis, we analyzed the effect of sphingosylphosphory1choline on cytochrome c release and caspase-3 activity. We must point out that the sphingolipid caused an increase of cytochrome c release from mitochondria to cytosol concomitantly with an increase of caspase-3 activity. Furthermore, a translocation of Bax was found, after sphingosylphosphory1choline treatment
Different sensitivity of neurons and neuroblastoma cells to quercetin treatment
Authors: Jakubowicz-Gil Joanna , Rzeski Wojciech , Zdzisińska Barbara , Piersiak Tomasz , Weiksza Katarzyna , Glowniak Kazimierz , Gawron Antoni
Published: November 2023

Quercetin is a natural flavonoid with pro-apoptotic and antiproliferative properties. In this study, we determined the sensitivity of neurons and neuroblastoma cells on apoptosis and necrosis induction upon quercetin treatment. No expression of Hsp72 was observed in neurons, which were more sensitive to cell death upon quercetin treatment than neuroblastoma cells, where Hsp72 expression was observed. Reduction of Hsp72 gene expression in neuroblastoma cells by antisense oligonucleotides made them more sensitive to pro-apoptotic action of quercetin. Moreover, the flavonoid decreased Hsp27, procaspase-3, MRP and PKB expression in neuroblastoma cells and in neurons. Nuclear localization of mainly cytoplasmic Hsp27 was observed in neuroblastoma cells after treatment with high quercetin concentrations, while in neurons, the protein was present in nuclei both in control and quercetin treated cells. Our results suggest that quercetin induce apoptosis more effectively in cells with low level of Hsp 72 expression. Higher sensitivity of neurons for cell death after treatment with high quercetin concentrations in comparison to neuroblastoma cell line should also be taken into consideration in further studies on using studied flavonoid as therapeutic agent.
Early postnatal ethanol exposure induces fluctuation in the expression of BDNF mRNA in the developing rat hippocampus
Authors: Miki Takanori , Kuma Hiromi , Yokoyama Toshifumi , Sumitani Kazunori , Matsumoto Yoshiki , Kusaka Takashi , Warita Katsuhiko , Wang Zhi-Yu , Hosomi Naohisa , Imagawa Tomohiro , Bedi Kuldip , Itoh Susumu , Nakamura Yu , Takeuchi Yoshiki
Published: November 2023

Effects of early postnatal ethanol exposure on brain-derived neurotrophic factor (BDNF) mRNA expression in the rat hippocampus were investigated. Wistar rats were assigned to either ethanol treatment (ET), separation control (SC) or mother-reared control (MRC) groups. Ethanol exposure was achieved by a vapor inhalation method for 3 hours a day between postnatal days (PND) 10-15. On PND 16, 20, 30, and 60, the expression of BDNF mRNA in the hippocampus was determined using real-time RT-PCR analysis. There was a significant age-related increase in the BDNF mRNA expression between PND 30–60 in MRC animals. The BDNF mRNA expression in ET rats was increased at both PND 16 and 20 and thereafter decreased at PND 60 compared to SC animals. Such age-related fluctuation in the expression of BDNF mRNA differed from that of MRC animals. The exact functional implications, if any, of these ethanol-induced changes in BDNF mRNA expression remain unknown although it can be speculated that they may have an effect on the behaviors known to be influenced by the hippocampal formation.
Pro-inflammatory cytokine TNF-alpha as a neuroprotective agent in the brain
Authors: Figiel Izabela
Published: November 2023

Despite the numerous reports on the role of tumor necrosis factor-alpha (TNF-alpha) in the brain neuropathology, very little is known about the mechanisms by which TNF-alpha may mediate neuroprotection. Different hypotheses pertain to the molecular and cellular effectors triggered by the activation of TNF receptors (TNFRI and TNFR2). They are focused on diminishing the production of nitric oxide and free radicals, alteration of excitatory amino acids neurotransmission, maintenance of neuronal calcium homeostasis and induction of neurotrophic factors synthesis. In this review all these data are summarized. Moreover, possible explanations for the inconsistent data concerning the TNF-alpha effect on neuron are discussed.
Laminin promotes oligogliogenesis and increases MMPs activity in human neural stem cells of HUCB-NSC line
Authors: Sypecka Joanna , Dragun-Szymczak Patrycja , Zalewska Teresa , Domańska-Janik Krystyna
Published: November 2023

Oligodendrocytes, the cells responsible for myelin formation and maintenance in CNS, are depleted in many acute and chronic conditions. The stem/progenitor cells stimulation or transplantation might be seriously considered as a long hoped for therapeutic perspective. Better understanding of the mechanism(s) regulating the activation of the cell lineage from the endogenous progenitor reservoir might be helpful. Therefore an efficient source of donor cells for transplantation in humans is being craved for. In this study we show that the application of extracellular matrix component-laminin promotes oligogliogenesis from neural stem-like cells of human cord blood cells (HUCB-NSC). Although oligodendrocytes constitute a minor subpopulation of spontaneously differentiated HUCB-NSC, the manipulation of active compounds regulating the process of cell commitment results in a several fold increase in their number. Thus cells of the HUCB-NSC line could be considered as a potential source of glial cells, fulfilling the suitable candidate criteria for oligodendrocyte replacement therapy.
Morphometric and volumetric analysis of the middle cerebral artery in human fetuses
Authors: Gielecki Jerzy , Żurada Anna , Kozłowska Hanna , Nowak Dariusz , Loukas Marios
Published: November 2023

The morphometrical and volumetrical changes of the middle cerebral artery (MCA) during the fetal period of development were analyzed by digital-image analysis system (DIAS). Examinations were performed on 304 MCAs from 152 brains of human fetuses ranging from the 12th to 40th weeks of gestation. MCAs were analyzed with respect to its branching from the internal carotid artery and its division into the main cortical branches. No statistically significant differences were found between the mean values of the diameter, length and volume of the left and right M1 segments of the MCAs in all studied age groups.
Interferon beta and glatiramer acetate induce proliferation of Schwann cells in vitro
Authors: Zanon Renata , Pierucci Amauri , Oliveira Alexandre
Published: November 2023

Techniques as well as substances capable of stimulating cultured Schwann cell (SC) proliferation are needed for future therapeutical applications. In this work, the effects of interferon beta (IFNbeta) and glatiramer acetate (GA) on SC cultures were tested, with interest on the growth curve and potential proliferative effects. Primary cultures were prepared from the sciatic nerves of neonatal rats and seeded onto culture plates. Such cells were then subjected to treatment with different doses of IFN beta (100, 500 and 1000 IU/ml) and of GA (1.2, 2.5 and 5.0 mmg/ml) for five consecutive days. S100beta and DAPI double labeling was used in order to confirm the purity of the cultures. Both treatment with IFN and GA resulted in an increased number of cultured SCs. However, only IFN beta induced a statistically significant proliferative outcome. Such results indicate that addition of IFN beta to the culture medium is efficient in order to improve SC proliferation in vitro.
In vitro-evaluation of lipid emulsions as vehicles for the administration of xenon: Interaction with NMDA receptors
Authors: Weigt Henry , Georgieff Michael , Föhr Karl , Adolph Oliver
Published: November 2023

The noble gas xenon is an antagonist of the NMDA (N-methyl-D-aspartate)-type glutamate receptor which may account for the ideal anesthetic profile and potent neuroprotective properties demonstrated even at subanesthetic concentrations. Because lipid emulsions also promote NMDA antagonistic effects they may serve as ideal carriers for xenon. In this in vitro study, we investigated the efficacy of xenon dissolved in various lipid emulsions (Intralipid(R), Lipofundin(R), ClinOleic(R) and Abbolipid(R)) on NMDA-evoked currents in cultured cortical neurons. The NMDA receptor blocking property at a clinically relevant concentration seen in the lipid emulsions tested may contribute to the anesthetic, analgetic and neuroprotective effects of xenon administered by way of these lipid carriers. AbbolipidŽ may serve as the most acceptable carrier since the NMDA antagonistic effect of xenon was enhanced in combination with this emulsion.
Thalidomide fails to be therapeutic following contusive spinal cord injury in rats
Authors: Reyes-Alva Horacio , Franco-Bourland Rebecca , Martínez-Cruz Angelina , Grijalva Israel , Fuchs Bruno , Madrazo Ignacio , Guízar-Sahagún* Gabriel
Published: November 2023

Mechanical damage to the spinal cord (SC) generates self-destructive processes that contribute to post-traumatic neurodegeneration. Because thalidomide apparently counteracts these effects its use clinically has been proposed enthusiastically. Nonetheless, we tested its action as a neuroprotectant in a clinically relevant model of SC injury in rats. We administered thalidomide intraperitoneally to rats subjected to thoracic SC contusion as single or repeated doses within the first 24 h after injury. Edema, neutrophil infiltration, and cord tissue preservation/destruction were assessed in the SC 24 h after injury and motor function for 7 weeks. Rats treated with thalidomide showed significant increase in SC water compared with naive rats, but not vehicle-treated rats; their neutrophil infiltration and amount of spared/destroyed cord tissue was not different from vehicle-treated rats; and in no case was motor performance improved after thalidomide. In conclusion, thalidomide failed here to be therapeutic, discouraging its use clinically for SC trauma.
Diverse functions of perineuronal nets
Authors: Karetko Magdalena , Skangiel-Kramska Jolanta
Published: November 2023

Perineuronal nets represent well-organised components of the extracellular matrix, which are surrounding cell bodies, dendrites, and axon segments of a particular class of neurones as well as forming lattice-like structures. The role of perineuronal nets is not fully elucidated yet. Perineuronal nets may play a beneficial role by stabilizing the extracellular milieu assuring the characteristic features of enveloped neurons and protecting them from the influence of harmful agents. On the other hand, perineuronal nets create a barrier which limits neuronal plasticity and counteracts regeneration. This review examines recent evidence concerning the significance of the occurrence of perineuronal nets.
UPAYA KEPALA SEKOLAH MENINGKATKAN KINERJA SEBAGAI LEADER DALAM MANAJEMEN MUTU TERPADU
Authors: Ulfa Maria , Shalahuddin Shalahuddin
Published: November 2023

School performance is important to create a culture of integrated quality management. The purpose of this research is to analyze and describe the efforts of school principals in managing integrated management. The research method used in this research is qualitative, using a descriptive approach. Collecting data using observation techniques, documentation, observation, and interview techniques. Data analysis used qualitative data analysis with the stages of data collection, data reduction, and conclusion. Based on this research, shows that the performance of UPT SMPN 26 Gresik principals as leaders can create school members who can achieve the goals of the school's vision mission and strategic plans. The performance of the school principal as a leader is: 1) holding socialization of the vision and mission that has been formed, which includes the goals and strategic plans of the school to internal and external customers; 2) reinforcing motivation to educators and educational staff to optimally improve performance with measurable achievements; 3) carry out coaching activities for teachers and school administrative staff with a structural and familial approach so that they contribute positively to the development of school quality; and 4) providing facilities to educators and educational staff to develop themselves through activities, such as training and workshops. Here the principal is expected to be a strong, tough, and professional leader.
Pengolahan Bakso Berbahan Jantung Pisang Pada Kelompok Jalapagos Desa Buon Mandiri Kabupaten Banggai Sulawesi Tengah
Authors: Lamusu Darni , Chaniago Ramadhani , Ode Haruni , Lasamadi Rahman Dani
Published: November 2023

Banana hearts are usually cut so as not to inhibit fruit growth and prevent disease in banana plants, so they are considered waste. Actually the banana heart can be processed into beef jerky or meatballs which are rich in fiber. Implementation of activities includes observation, preparation, implementation and evaluation. The results of the implementation of training in making banana heart meatballs can increase knowledge and skills of mothers who are members of the Jalapagos group, about the potential of banana plants, namely banana flowers, which can be a new source of income so that they can improve the welfare of the community in Buon Mandiri village, Banggai district, Central Sulawesi. Then the community really expects the training activities as it has been implemented to continue to be carried out.
Management and Distribution Clean Water Technology for Village Tour Mountain Buthak Purworejo
Authors: Suyitno Suyitno , Qomariyah Nurul , Fatmaryanti Siska Desy , Widiyono Yuli , Iskandar Faruq
Published: November 2023

This community service activity aims to develop a tourist village through the distribution of clean water in the Gunung Buthak tourist village of Tlogokotes Bagelen , Purworejo , Central Java. The participants in this activity were members of the Pokdarwis awareness group for Mount Buthak tourism. This activity consists of three stages, namely planning, implementation, and evaluation. The method applied is counseling and workshops on clean water management.The results of the evaluation show that the community service activities have been carried out properly. The participants were also enthusiastic and actively participated in this activity. This is shown from the evaluation results which show an increase in community knowledge about the use and distribution of clean water as a form of village tourism marketing. With the implementation of this activity, it is hoped that Mount Buthak tourism can be widely known by tourists so that many tourists visit Mount Buthak so as to increase the economic value and welfare of the local community.
Pembinaan kepada Kaum Muda Mengenai Jodoh dan Pekerjaan di Jambore Gereja Kristen Kerasulan Indonesia 2022
Authors: Sunarto Sunarto , Prianto Robi , Tampubolon Yohanes Hasiholan , Tiladuru Vena Melinda , Selan Yustus , Sihombing Aeron Frior
Published: November 2023

Youth is a period full of energy and high enthusiasm to gain knowledge and experience in order to achieve what you want. In the midst of globalization and technological advances, it is hoped that young people will not only be able to develop themselves, but also play a role as inheritors and successors of Christian values for a church. Seeing this fact, the implementation of guidance regarding matchmaking and work was carried out by the PkM team of the STT SAPPI Theology Study Program at the 2022 GKKI Youth Jamboree for 1 day and 2 meetings. Based on the results of joint activities with GKKI youth, it was concluded that the participants participated enthusiastically in the activities when they heard and discussed the material presented. This means that the topic of marriage and work is a very relevant topic for the lives of youth and adolescents. In the midst of the rapid development of contemporary values, youths are also expected to have Christian values that can become their guide, especially when considering issues related to their mate and work.
Sosialisasi Akad-Akad Transaksi Keuangan Syariah Pada Siswa Akuntansi SMK Satria Jakarta
Authors: Astuti Retno Puji , Wahyuni Putri Dwi , Marlina Rini
Published: November 2023

There are many provisions that must be carried out for a Muslim in doing business. The provisions that have been stipulated in the Qur'an and hadith, which make Muslims obey the teachings of Islam, besides that the provisions also bring benefits to the benefit of human life. In practice, sharia transactions are free from elements of usury, gharar, and maysir. To avoid these things, a contract is made that underlies the transaction so that it is safer and does not harm both parties. The purpose of this community service activity is to increase the comprehensive and integrative understanding of students majoring in accounting at SMK Satria Jakarta regarding contracts in Islamic financial transactions. This activity is also in line with government programs to increase Sharia transactions which will contribute to the National economy.  This activity is carried out by conducting socialization of Islamic financial transaction contracts through a virtual room in the zoom application. With this training, students gained additional knowledge about Islamic financial transaction contracts and the participants were satisfied with the material that was socialized.
Upaya Meningkatkan Kesadaran Dalam Melestarikan Sumber Daya Alam Melalui Media Sosial Bagi Generasi Muda Ciliwung
Authors: Wijayanti Vera , Sary Marisa Puspita , Putri Angieta Dewati , Wulandari Helyana , Fauziyah Hasna Nur
Published: November 2023

The declining concern of the younger generation towards conserving natural resources. Natural resources are natural resources that are utilized by humans to meet the needs of life, not only humans but every living creature needs natural resources to fulfill their lives. The achievement targets in this community service activity are: (1) Increasing awareness in preserving natural resources in the younger generation, (2) Increasing the motivation of the younger generation in preserving natural resources, and (3) Expanding natural resources that are maximally utilized by the younger generation. The place of this community service activity was carried out at the pavilion owned by the Mat Peci Ciliwung Community. The training ctivities were attended by members of the Mat Peci Ciliwung Community
Motivasi Belajar Terhadap Hasil Belajar Siswa Di SMP Negeri 2 Pancalang
Authors: Putri Fadhlika Mulyawati , Darwan Darwan
Published: November 2023

Motivation is one of the most important factors in influencing learning and learning outcomes for students at the kindergarten, elementary and junior high school levels.  However, in learning activities, it turns out that there are still students who are less active in participating in learning during the lesson.  Students or students still look lazy to learn.  Students also do not show their expressions that are happy and not enthusiastic in following ongoing learning.  Their attention is more focused on something that is opposite them than their learning tasks such as playing games in class and others. Learning motivation has a positive relationship with the learning outcomes of a subject. Thus, learning motivation contributes greatly to the achievement of student learning outcomes. Therefore, teachers must have the ability: (First) encourage learning motivation, (Second) directing learning motivation to achieve goals in achieving the learning outcomes of a subject, and (Third) strengthen learning motivation in order to ensure the consistency of students learning actions.
Optimalisasi Literasi dan Peningkatan Nilai Gizi Terhadap Masyarakat melalui X Banner
Authors: Pratiwi Indah , Jannah Rizky Mifthakul , Dyatin Rochmad Nur , Handayani Tri Mega , Dasmadi Dasmadi
Published: November 2023

Some of the activities that have been carried out refer to the importance of literacy, increasing nutritional value by processing local food, as well as public services through x-banners. In this increasingly advanced era, the use of technology and social media has become an inseparabel part of the current generation’s daily life. This is a new challenge for the people in Tempursari Village, namely a lack of interest in reading and a lack of information for public services. The implementations of these work programs intends to stay in touch and collaborate with the people in Tempursari Village. The problems faced by the community include limited media. Students have made efforts to increase the knowledge and skills of the Tempursari Village community in literacy, local food processing, and the presentation of public service information through X Banners.
Penyuluhan Penguatan Profil Pelajar Pancasila di SMA Negeri 2 Majene
Authors: Rahman Abdul , Najamuddin Najamuddin , Ahmadin Ahmadin , Tamrin Sopian
Published: November 2023

Education is not only related to academic knowledge, but also involves building the character of students. Character education aims to form good attitudes, values and behavior in students. The Pancasila student profile can be a comprehensive framework to guide students in developing good character. On this basis, service activities to disseminate and strengthen the profile of Pancasila students in the school environment need to be carried out, especially at SMA Negeri 1 Majene. Counseling is carried out by building dialogue between the service team and the school including teachers, students and education staff. The results of the service show that the Pancasila Student profile program is well understood by the participants. They try to combine Pancasila values with religious values and local wisdom.
Pemberdayaan Anak Dengan Sosialisasi Dampak Penggunaan Gadget Dalam Rangka Memperingati Hari Anak
Authors: Pelu Musa , Firdiyanti Errysa Ayu , Prasetyowati Rachma Intan , Safera Tessa Bela
Published: November 2023

This study discusses the impact of Gadget use on students at SDN Joho 02. Gadgets have become a commonly use d communication tool in various circles, including children. Gadgets have positive benefits by increasing children's knowledge and creativity, but can also have negative effects if used excessively. Gadget addiction can lead to poor academic performance, lack of enthusiasm for learning, and lack of time discipline.This research uses a descriptive method combined with lecture, discussion, and question-and-answer methods. The media used to socialize the impact of using Gadgets is posters. The results showed that many students are addicted to Gadgets, which reduces their chances of success. Socialization of the impact of Gadget use was carried out by understanding the dangers of excessive Gadget use, as well as giving challenges to participants to reduce Gadget use for one week. Based on the results of the socialization conducted by the KKN UNS team, it can be concluded that the socialization of the impact of Gadget use on elementary school students went smoothly and according to plan. Elementary students gained positive knowledge and experience in managing the use of Gadgets. This activity will help students use Gadgets more wisely.
Analisis Pengembangan Skula Kompos Berbasis Kegiatan Pemberdyaan Masyarakat (Studi Kasus : PT. Solusi Bangun Indonesia Tbk Pabrik Cilacap)
Authors: Prasadi Oto , Prastya Andika , Fauzi Muhammad , Nurochman Budi
Published: November 2023

The compost school (skula kompos) is a product of community empowerment activities that focuses on developing education on household-based organic waste management. This program is one of a series of innovations in the Baruwani Program (Bala Runtah Watu Geni) which was initiated in 2019 by PT Solusi Bangun Indonesia Tbk, Cilacap factory. The baruwani program itself focuses on waste sorting and processing activities in the community where the output produced not only reduces waste generation, but produces other innovations, especially to support the successful use of waste as an alternative fuel to replace coal in the cement production process. The benefit of making this compost is to help people optimize the use of household waste so that it can have high use value and be useful as compost fertilizer which in the next stage can be used to support urban farming activities. Making compost and being able to reduce dependence on the use of inorganic fertilizers which contain many compounds that are less environmentally friendly, has the potential to become a social business that has an economic impact. Skula kompos is a forum for outreach and training which is attended by baruwani's assisted communities and other parties who are interested in making compost using the unique method of Skula kompos BSM Subur.
Pemanfaatan Kain Perca Menjadi Produk Bernilai Jual Tinggi Pada Ibu Rumah Tangga di Desa Plosokuning
Authors: S Fabiani Rengganesti , Fii Ahsani Riska , Indiana Rindianita Seftia Bella
Published: November 2023

In the new normal era after the Covid-19 pandemic, people's needs in Indonesia are increasingly high, but job opportunities are also limited to college graduates and those with certain age limits. There are still quite many people who are unemployed and hope to find work to make a living. Therefore, the best solution to this problem is to create an independent economic source by utilizing waste in the surrounding environment to become handicrafts with high selling value. Many innovations have emerged in the use of waste, such as patchwork waste which can be obtained easily, and can become a craft that has value for sale. The author chose the location of Plosokuning Village as a place to carry out the community service program. Plosokuning Village is in Minomartani Subdistrict, Ngaglik District, Sleman Regency, Yogyakarta City. The average job for the people of Plosokuning Village is as farmers and vegetable seller. The aim of this community service program is to provide skills in making crafts from patchwork to increase independence and open economic opportunities for the community, especially housewives to help the family economy.
Upaya Meningkatkan Kreativitas dan Minat Belajar Anak di Kelurahan Sudiroprajan
Authors: Ahmad Firjatullah Fikri Nur , Wati Nori Laras , Martandang Lailatul Bilkisa Putri , Adiba Al Adawi Habibah Amalia Rosa , Afifah Nida Nur , Rizkhy Pratama Dhimas , Maharani Galuh , Christina Manurung Gita , Nur Azizah Juwita , Kurnia Oktaviani Leny , Adi Kurniawan Dadan
Published: November 2023

In fact, there are still many children who have low creativity and interest in learning. There are PAUD schools that do not pay attention to their suitability in terms of buildings, educational resources, and there are elementary/middle school age children who prefer to spend time in one place playing games rather than studying together. KKN activities were carried out in Sudiroprajan Village, Jebres, Surakarta, Central Java. The methods used in this service are observation, socialization, mentoring and evaluation methods. As a result of observation and interview activities, problems were found to be provided for solutions through several work programs, namely literacy and numeracy through play activities, clean and healthy living education activities, coloring and drawing competitions, and study guidance. literacy and Numeracy through Play Activities improve literacy and numeracy skills. PHBS activities attract the interest of Cempaka PAUD children to maintain cleanliness and health. Drawing and coloring competition activities to develop the creativity of children in Sudiroprajan Village. Tutoring so that Sudiroprajan's children are enthusiastic about learning, as well as helping children who have learning difficulties. KKN 37 FKIP in Sudiroprajan Village has succeeded in providing a significant positive impact in developing the potential and quality of life of children in the area. Through various initiatives such as literacy and numeracy through play activities, PHBS counseling, drawing and coloring competitions, and tutoring, KKN students have made significant contributions in terms of children's education, health, creativity and learning motivation.
The Use of ICT as a Resource and Media for Modern 21st Century Learning in Primary Schools
Authors: Prihantini Prihantini , Sutarto Sutarto , Punggeti Ratna Novita , Rukmini Ai , Intes Amina
Published: November 2023

The advancement of technology and information makes human life easier, but at the same time it makes some humans lack morals and behave badly due to lack of socialization. Behind all the bad impacts on the development of technology, there are also positive impacts in it, such as in the field of education. One of the positive impacts is ICT (Information and Communication Technology) learning media. The purpose of this study is to determine the use of ICT (Information and Communication Technology) as a Source and Media for Modern 21st Century Learning in Elementary Schools. This research uses quantitative methods, data obtained from distributing questionnaires and through interviews. The results of the study explain that the usefulness of ICT (Information and Communication Technology) as a source and modern learning media in elementary school children is very useful and helps students in carrying out learning. The conclusion of this study explains the usefulness of ICT (Information and Communication Technology) as a source and modern learning media in elementary school children is very helpful in the learning process. The researcher realizes the limitations of this study were only conducted in elementary schools in one of the districts in West Sumatra province, the researcher hopes that future researchers can conduct the same research with a wider range in order to continue this research. Researchers also recommend to researchers who will continue to be a benchmark in conducting research related to the use of ICT (Information and Communication Technology) as a modern learning resource and media in elementary schools.
Analysis of the Meaning of Repetition Language Style in Hermann Hesse's Der Steppenwolf Roman
Authors: Purwanto Anim , Zuriyati Zuriyati , Anwar Miftahulkhairah
Published: November 2023

Repetitive language style in romance literary works is not only used to create aesthetic effects, but also creates emotional and intellectual resonance that enriches the reading experience. This study aims to analyze the meaning of repetition language style in the romance Der Steppenwolf by Hermann Hesse. The research uses descriptive qualitative method with semantic analysis approach. The analysis revealed that anaphora is the most dominant language style used, with the amount of data reaching 40.74%, followed by epistrophe around 31.48%, and polysyndeton 27.78% of data. Meanwhile, the meaning of repetition language style includes strengthening the character's feelings towards the world, providing structure and rhythm to the story, creating nuances and deep emotions. Repetitive language styles in romances can provide new insights into how literary works are constructed and influence readers.
Development of the Edpuzzle Platform as an Audio Visual Learning Media for Arabic Language Learning at Madrasah Aliyah
Authors: Rachman Andy , Sutisna Dede , Sopiandi Li , Khalik Muh Fihris , Nitin Mahon
Published: November 2023

The development of technology is currently growing so rapidly, various applications and online media are becoming increasingly popular to be used as learning media, including Youtube and Edpuzzle which can be used as learning support platforms with interactive, effective and fun video media for students. Arabic language learning with audio visual is needed by madrasah Aliyah students, so that learning is not boring and more interesting. This research aims to develop the Edupuzzle platform as an audio-visual learning media for Arabic language learning in madrasah Aliyah. The method used in this research is research and development with the Kemp model. Kemp's model is a learning design model designed in the early part of education aims to provide guidance to learners to think about general problems and learning objectives. The results of this study explain that the Edpuzzle platform can be used as audio-visual learning media in learning Arabic with audio visuals that can facilitate students in learning Arabic online. The conclusion of this research is that the Edpudzzle platform can be used as a learning medium for teachers, especially in Arabic language learning. the limitation of this research is that researchers only conduct research on the Edpudzzle platform for Arabic language learning, for that researchers hope that future researchers can conduct research with the same platform but more explained to support the teaching and learning process in other subjects.
Envelheci e agora? Habilidades sociais como estratégia para o envelhecimento ativo
Authors: Birck Débora , Perico Elena , Carvalho Hanriéli , Soares Nandra Martins
Published: November 2023

A velhice corresponde à última fase do ciclo vital, sendo a etapa da vida acometida pela involução das funções, acarretando em perdas das habilidades cognitivas, motoras, mentais e consequente isolamento ou distanciamento social. Nesta etapa da vida as Habilidades Sociais (HS) podem ser consideradas uma grande aliada, sendo que idosos com um vasto repertório de HS são mais assertivos, possuem clareza na comunicação, maior facilidade para exposição de sentimentos e para tomada de decisão, tornando as relações interpessoais mais saudáveis. Diante disso, o presente estudo tem por objetivo verificar se a participação no Centro de Convivência do Idoso exerce influência no repertório de HS em idosos, a partir de uma pesquisa de campo, realizada com 80 idosos de ambos os sexos com 60 anos ou mais. A amostra foi dividida em dois grupos, 37 idosos que frequentam o Centro de Convivência e 23 idosos que não frequentam. Para a seleção e caracterização da amostra foi aplicado um questionário sociodemográfico e o Mini Exame do Estado Mental e para a avaliação das HS, o Inventário de Habilidades Sociais. A partir dos resultados, verificou-se que o Centro de Convivência do Idoso não teve grande influência no repertório de HS em comparação com os idosos não participantes do centro, uma vez que os resultados de habilidades sociais não apresentaram diferença significativa entre os grupos (p= 0,95). No entanto, e considerando a mudança do perfil demográfico atual, sugere-se a criação de mais políticas públicas voltadas para a população idosa, as quais precisam ser eficientes e capazes de promover o bem-estar físico, mental e a qualidade de vida na velhice.
Efeito do estresse hídrico na produtividade da soja
Authors: Alves Ryckson Eros Almeida , Gomes Maryjane Diniz de Araújo , Veloso Samara Valena , Lima Lucas Fernando da Costa , Lélis Alexandre da Trindade , Palma Márcia Cristina Melo Monte , Da Silva Félix Lelis , Da Silva André Luiz Pereira
Published: November 2023

Os diferentes processos biológicos da soja (Glycine Max.) podem ser afetados pelo nível de estresse hídrico, dependendo de seu estádio fisiológico. O modelo experimental foi o em Blocos ao Acaso em esquema Fatorial (4 x 2) com 4 níveis de água (T0 =100%, T1 = 80%, T2 = 60%, T3 = 40% da ETc), com dois tratamentos de cobertura de solo (com e sem cobertura) e 4 repetições, totalizando 64 parcelas representadas por vasos individuais com capacidade de 18 L. Foi realizado o teste de tukey a 5% de probabilidade e considerando que a análise era um modelo fatorial, foi utilizado um modelo de regressão. A cobertura do solo com palhada de milho, mantém a umidade do solo e influencia positivamente as características morfológicas das plantas.
Percepções políticas e econômicas sobre a pandemia da Covid-19 e seus reflexos no espaço urbano brasileiro
Authors: Cirino Douglas Soares , De Arruda Ana Paula Serpa Nogueira , Soares Wilson Sebastião Rodrigues , Viana Aurimar de Paula , Rangel Daniel Andrade , Verdan Mateus Fernandes , Abud Natália Assed Bastos
Published: November 2023

A gestão das cidades brasileiras passou a contar com novos contornos e nuances, a partir das intercorrências acarretadas pela pandemia da Covid-19, sentida ao longo do ano de 2020. Inúmeros foram os reflexos políticos e econômicos impostos à sociedade brasileira, dentre os quais o debate quanto à fixação de competências administrativas e legislativas para adoção de medidas de enfrentamento, limitações da intervenção forçada nas liberdades individuais, formatando a quarentena social, bem como as ações governamentais implementadas na seara econômica, com vistas a reduzir ou arrefecer os  impactos da crise, notadamente o aumento do desemprego, a elevação dos gastos públicos, a mutação do comportamento de consumo, dentre outros. A partir de uma atenta revisão de literatura, sobreposta à realidade fática que delineia o fenômeno, ora vivenciado, buscou-se sua compreensão sob a ótica da dinâmica urbana, atentando-se a pertinentes reflexões.
Manejo farmacológico de pacientes em cuidados paliativos em uma unidade de tratamento oncológico
Authors: Porto Thayron Ranyere Brilhante , Giacomin Melissa Marra Cesário , Da Silva Laila Cristina Nunes , Fernandes Jorge Luis Nunes , Silva Diego de Sousa , Da Silva Gabriel Borba Rodrigues , Porto Thallyson Ruan Brilhante , Pinto Julliana Varella Pereira
Published: November 2023

Os cuidados paliativos ainda sofrem grande resistência devido à dificuldade de entendimento de familiares, pacientes e dos profissionais da área da saúde a respeito do conceito, indicações, manejo de sintomas e do seu benefício. Dentro dos cuidados paliativos, está o alivio dos sintomas físicos, para isso, a Organização Mundial da Saúde anualmente produz uma lista modelo de medicamentos essenciais, que apresenta as necessidades mínimas de medicamentos para um sistema de saúde, abrangendo fármacos sintomáticos para pacientes em cuidados paliativos. Foram coletados os dados, de acordo com o Instrumento Padronizado de Coleta de Dados – Modificado pelo autor, nos prontuários selecionados para a pesquisa. Posteriormente, foram analisados os dados coletados e realizado geração de gráficos, sendo correlacionados com a 22º lista modelo de medicamentos essenciais da OMS e outras referências. Foram registradas 447 queixas dos cinco sintomas estudados. Os pacientes queixaram de dor 237 vezes (53,02%); de dispneia, 68 vezes (15,22%); de vômito, 63 vezes (14,09%); de náuseas, 47 vezes (10,51%); e, de constipação intestinal, 32 vezes (7,16%). O resultado de cada sintoma foi dividido em três grupos. O grupo A representa os pacientes que receberam tratamento medicamentoso para seu sintoma conforme a 22ª lista de medicamentos essenciais da OMS. No grupo B, estão pacientes que receberam tratamento para sua queixa, mas com medicamentos que não estão listados pela OMS. O grupo C, representa aqueles que não receberam medicamentos direcionados para o sintoma. Dos pacientes com sintoma de dor, 87 (36,71%) se condizem com a grupo A, 145 (61,18%), no grupo B e 5 (2,11%) no grupo C. Das queixas de dispneia, 28 (41,18%) condizem com a grupo A, 25 (36,76%) com o grupo B e 15 (22,06%) com a grupo C. Referindo de vômitos, no grupo A, 51(80,95%), no grupo B, 10 (15,87%), no grupo C, 2 (3,17%). Com náuseas 40 (85,11%) se enquadraram no grupo A, 5 (10,64%) no grupo B demonstra e 2 (4,26%) no grupo C. Relatando constipação, 12 (37,50%) se enquadram no grupo A, 10 (31,25%) no grupo B e 10 (31,25%) no grupo C. Diante dos dados coletados durante a pesquisa, é possível perceber que nem sempre os pacientes oncológicos, em cuidados paliativos, têm seus sintomas manejados da forma mais adequada ou, se quer, receberam tratamento para sua queixa.
Os mecanismos que possibilitam a aplicação do princípio da capacidade contributiva à tributação indireta incidente sobre os gêneros alimentícios da cesta básica
Authors: Gonçalves Alex Silva , De Araújo Dylvan Castro , Farias Giácomo Tenório , Leal Janaine Marques , Santos Livio Augusto de Carvalho , Morais Manuela Saker , Campelo Filho Mussoline Batista , De Sousa Paulo Phitágoras Rodrigues , Monteiro Wesley Gomes
Published: November 2023

O objetivo do presente artigo é analisar os instrumentos tributários que viabilizam a aplicação do princípio da capacidade contributiva de forma a proteger o mínimo existencial mesmo diante da ambiguidade e vagueza do conteúdo e alcance tanto do princípio da capacidade contributiva quanto do mínimo existencial. Neste contexto, a problemática é: Como viabilizar a aplicação do princípio da capacidade contributiva (fundamentalmente quanto à tributação indireta), tendo em vista sua lacunosa redação constitucional, de forma a proteger o mínimo existencial? Para a elaboração do presente artigo, pesquisa desenvolvida foi qualitativa do tipo documental bibliográfica, o método de abordagem escolhido foi o dedutivo e como método de procedimento foi adotado o método monográfico. Os resultados alcançados foram que é necessário a criação de um imposto sobre o valor agregado, substituindo toda a carga tributária indireta, com a previsão de alíquotas fixadas em razão da essencialidade da mercadoria ou do produto, devendo constar dentre estas alíquotas uma alíquota zero para alimentos que compões a cesta básica ou outras mercadorias e produtos definidos pelo legislador infraconstitucional como elemento integrante do mínimo existencial.
Diversidade alfa e beta de fragmentos de Cerrado, região norte da Amazônia legal
Authors: Lopes Valeria Cardoso , Da Silva Renata Carvalho , Amorim Marcos Vinicius de Melo , de Moraes Thatiele Pereira Eufrazio , Bispo Amanda Carine , Alvarez Sergisclei Ferreira , Lopes Tatiana de Souza , De Souza Priscila Bezerra
Published: November 2023

O estado do Tocantins já foi detentor dos maiores índices de vegetação remanescente do bioma Cerrado, com cerca de 90% do seu território sob o domínio Cerrado e 9% sob o domínio Amazônico, e está sujeito a pressão antrópica por fazer parte do Matopiba. A coleta de dados foi desenvolvida em três áreas de fitofisionomia de cerrado sensu stricto, inseridas na região norte da Amazônia Legal, sul do estado do Tocantins. Para comparar e avaliar a ecologia alfa entre as comunidades analisadas foram utilizados os índices de diversidade de Shannon-Wienner (H’) e equabilidade de Pielou (J’). A diversidade beta das quatro áreas comparadas foi avaliada através dos índices de similaridade de Sørensen, esse índice compara qualitativamente a presença e ausência de espécies na área, variando em uma escala de 0 a 1, respectivamente. Foram amostrados nos quatro fragmentos de cerrado sensu stricto um total de 6526 indivíduos. A diversidade alfa das áreas comparadas e analisadas apresentaram valores entre 2,842 a 3,65 nats/indivíduo para o índice de Shannon-Weaver e para o índice de Pielou os valores variaram de 0,72 a 0,8. Em realação a diversidade beta, cerca de 70% dos valores foram abaixo de 0,5 de similaridade, o que indica uma diversidade beta elevada.
Overview about four different types of MQ sensors typically applied to IoT devices leak detection to flammable gases as a gas liquefied petroleum that is used on Brazilian kitchens
Authors: Lima Filho Marcos Camargo , Fernandez Marcial Porto , Pimentel Luciana Oliveira
Published: November 2023

Considering the current scenario increasingly conducive to the use of technologies like the Internet of Things (IoT), and the growing change in the expansion of the use of connected networks and aiming to meet in the problem of LPG leak safety in the household, at places that are not have regulations that require the use sensors, both in the public and private sectors, that can mitigate operational risks in the use of flammable gases such as LPG (Liquefied Petroleum Gas) which is the most used gas for cooking food or in water heating in Brazil. This study seeks to present the consolidation of results on pre-liminary tests with four types of sensors that detect hydrocarbons and determine which of them may be more promising in the use of LPG detection, which may in the future be applied to a low-cost and Open Source IoT device.