bluuebunny/crossref_metadata_2025 huggingface dataset:
Closed Loop Subject-Independent SSVEP Frequency Detection System Using CCA Features and Ensemble Learning Methods
Authors: Esfahani Moein , Najafi Hosein , Sadati Hossein
Published: June 2024

Purpose: In recent years, the use of Steady-State Visual Evoked Potentials (SSVEPs) in Brain-Computer Interface (BCI) systems has dramatically increased across several fields, such as rehabilitation, cognitive impairment, and brain disease or disorder detection, as well as artificial limbs, wheelchairs, and biomechanical systems. In this study, a novel method is proposed to help scientists develop more efficient BCI systems for Machine Learning Operations (MLOps). This study proposed a state-of-the-art method for detecting SSVEP-based stimulation frequencies with statistical models to design an optimal BCI system.
Materials and Methods: In this study, the Canonical Correlation Analysis (CCA) method has been implemented to extract features from the accessible-to-the-public Tsinghua University Benchmark dataset. A limited number of subjects are being studied. After completing feature selection methods and selecting the best subset of features using a specified feature selection method, the classification of the best features using machine learning-based classification methods has been completed. Furthermore, it is assumed that scientists will design and implement a system specifically for subjects. Models work for subjects independently. However, because model training is subject-specific, we must execute the proposed methods on each subject separately.
Results: The findings indicate that the novel suggested BCI system achieves an average accuracy of 83±9% in stimulation detection, which is higher than that of the traditional CCA approach with an accuracy of 80±11% (p<0.05).
Conclusion: Based on the findings, we demonstrated an increase in accuracy with the novel method. It was also discovered that by using the proposed techniques, it is possible to keep MLOps systems as an advantage.
A Wearable Device-Based System: The Potential Role in Real-time and Remote EEG Monitoring
Authors: Palumbo Arrigo , Gramigna Vera , Calabrese Barbara , Ielpo Nicola , Demeco Andrea
Published: June 2024

Purpose: In recent years, the Electroencephalography (EEG)-based Brain-Computer Interface (BCI) application has been growing rapidly and has emerged as a technology with high translational potential since it allows disabled people to translate human intentions into control signals and to interact with the external environment without any kinesthetic movement. Individuals with significant health problems can benefit from this technology to improve their independence and facilitate participation in activities, thus improving general well-being and preventing impairments. The rapid advances in technology have led to optimal innovation in the context of wearable health monitoring and remote control solutions. Many wearable devices for capturing EEG signals in daily life have recently been released on the market. Our paper aims to present a wearable de-vice-based system for real-time and remote EEG monitoring, to describe the proposed system modules and the signal processing algorithms, to explore the functionalities of this wearable EEG solution, and to suggest its potential application for daily brain data recordings in the home environment.
Materials and Methods: The validity of the Emotiv Epoc+ device in the continuous and real-time EEG signals acquisition and monitoring was demonstrated by means of preliminary test measurements during a resting state paradigm performed by a healthy control subject.
Results: Our findings confirmed the Epoc+ reliability for event-related brain potential research and in measuring acceptable spectral EEG data.
Conclusion: The described approach, focusing on the emerging area of remote monitoring sensors and wearable device applications, might be leveraged to measure complex health outcomes in non-specialist and remote settings.
Ultrasonic Evaluation of Muscle Echogenicity in the Lower Limbs for the Detection of Diabetic Peripheral Neuropathy
Authors: H. Abdulkareem Sally , H. Ameer Abdulnasir
Published: June 2024

Purpose: This study aimed to test the ability of high-frequency muscle ultrasound in detecting changes in muscle Echo Intensity (EI) in patients with type 2 Diabetes Mellitus (T2DM) and to correlate muscle ultrasonography findings with Nerve Conduction study (NCS) parameters in those patients. Additionally, we aimed to assess the usefulness of muscle ultrasound in diagnosing diabetic peripheral neuropathy.
Materials and Methods: In this case-control study, 26 diabetic patients with Diabetic Peripheral Neuropathy (DPN) and 25 controls were enrolled. Among the controls, 15 were healthy individuals, and the remaining 10 were diabetic patients without DPN. All participants underwent Nerve Conduction Studies (NCS) of the peroneal and tibial motor nerves, as well as quantitative muscle ultrasound. Ultrasound (US) images of the Abductor Hallucis (AH) muscle, Tibialis Anterior (TA) muscle, and Rectus Femoris (RF) muscle were taken and analyzed using grayscale analysis to measure quantitative Echo Intensity (EI). A comparison between the groups regarding EI was made, and correlations between NCS and quantitative US results were assessed.
Results: Our Study unveiled a statistically significant augmentation in muscular EI within two of the scrutinized muscle groups among individuals afflicted by DPN, relative to the control cohorts. Moreover, a noteworthy correlation was discerned between the parameters of NCS and muscular EI.
Conclusion: Quantitating muscle EI using grayscale analysis of US images is a useful supplementary test for the detection of DPN.
Turmeric as a Gut-Microbiota Modulator for Cardio-Metabolic Risk Factors: An Updated Comprehensive Review
Authors: Roshanravan Neda , Fatemeh Askari Sayyedeh , Fazelian Siavash , Morshed Behbahani Bahareh , Arjmand Babak , Namazi Nazli
Published: June 2024

Turmeric is a medicinal herb with antioxidant and anti-inflammatory components that can affect metabolic parameters via various pathways, including the gut-brain axis. Although positive effects of turmeric on health have been reported, findings are conflicting. Accordingly, the current review aimed to provide an overview of the biochemical and biological characteristics of turmeric and examine the impacts of turmeric on cardio-metabolic risk factors with a special focus on its abilities to modulate gut microbiota. In the present comprehensive review, findings of systematic reviews/narrative reviews, clinical trials, animal, and in vitro studies on turmeric in the English language published between 2010 and March 2023 were summarized. Findings revealed that turmeric is a safe medicinal herb with mild gastrointestinal side effects in some cases. It can help improve the glycemic status, lipid profile, and blood pressure. However, food processing and fermentation can affect the bioavailability of its effective components, including curcumin. Several mechanisms, including those affecting intestinal microbiota diversity, intestinal permeability, inflammatory and oxidative pathways, are proposed for their positive effects on metabolic factors.   However, due to high between-study heterogeneity, limited high-quality clinical trials, differences in the duration of the intervention, and the form of turmeric supplement, more studies on each metabolic parameter are needed to determine effective dosages and confirm its efficacy as a complementary therapy to modulate microbiota and cardio-metabolic parameters.
E-PARTICIPATION IN THE TERRITORIAL COMMUNITIES OF UKRAINE IN THE TIME OF EUROPEAN INTEGRATION PROCESSES: ELECTRONIC PETITIONS
Authors: Mykhalchuk B. S.
Published: June 2024

The article examines the processes of implementation and effectiveness of electronic petitions in the context of public participation in Ukraine in recent years. The issue of introducing democratic innovations and e-participation in communities is considered, on the one hand, inextricably linked to the ongoing processes of Ukraine’s accession to the European Union, and, on the other hand, taking into account the challenges and limitations caused by the Russian full-scale war and the introduction of martial law in Ukraine. Electronic petitions are identified as an effective additional mechanism that can serve as a “public voice” at critical moments in the implementation of democratic reforms, recovery and reconstruction processes.
Today in Ukraine, petitions are more common at the national level than at the local level. To analyze the state of use of the tool, we collected data from open sources, namely the EDEM digital platform (15 communities), local government websites (7 communities), and an earlier analytical study by the NGO “Chesno Movement”.
The study focuses on the key factors that can affect the effectiveness of local governments in directly generating quality policies and implementing such participatory forms on the ground. These factors include security criteria; legislative conflicts caused by the introduction of martial law; physical and psychological exhaustion of employees, which affects the efficiency of service delivery and information; and technical problems.
The conclusions note that in the process of effective use of electronic petitions, the key issue is the clear regulation of the procedure for applying the tool in the community charter, as well as the institutional capacity of the local self-government body to ensure a communication campaign on the availability of such a tool and further consideration of the received petitions in accordance with the procedure set out in the charter. Recommendations are made to improve the effectiveness of implementation of participation tools and involvement of citizens in these processes at the local level in general and in the case of electronic petitions in particular.
UKRAINE’S PARTICIPATION IN PEACEKEEPING MISSIONS OF INTERNATIONAL ORGANIZATIONS IN THE PRE-WAR PERIOD
Authors: Holopapa V. I.
Published: June 2024

The article analyzes Ukraine’s participation in peacekeeping missions of international organizations, particularly the United Nations and the North Atlantic Treaty Organization. The purpose of the article is to examine Ukraine’s influence on peacekeeping processes, with a focus on legislative changes and initiatives aimed at strengthening international law and the protection of peacekeepers. Key issues requiring further development are identified, such as the need for improved strategic planning and legislative development.
The article focuses on global changes in international relations caused by globalization processes and identifies the role of international organizations in preventive measures and conflict resolution. Ukraine’s contribution to peacekeeping operations since its declaration of independence includes initiatives aimed at enhancing the UN’s peacekeeping capacity and changes in legislation regulating the country’s participation in international peacekeeping operations.
The article emphasizes the importance of the experience gained by Ukrainian military personnel during their participation in peacekeeping missions for maintaining the combat readiness of the Armed Forces of Ukraine, and highlights the financial aspects of the country’s participation in international peacekeeping operations. It identifies the need to further expand the civilian component in peacekeeping activities and focuses on the importance of involving qualified police and legal personnel, particularly through the improvement of the national training system for specialists and the creation of a national peacekeepers’ registry.
Ukraine’s participation in peacekeeping operations of international organizations like the UN and NATO enhances the country’s international image, develops its defense capabilities and military experience, and creates new opportunities for international cooperation in ensuring global security. The conclusions of the article underline the strategic importance of peacekeeping activities for strengthening Ukraine’s international status and supporting its Euro-Atlantic integration.
Transactions with Residential Premises That Involve Minor Citizens
Authors:   Associate Professor of the Department of Civil Law and Procedure of the Belgorod University of Cooperation, Economics and Law, PhD (Law), Associate Professor, Poberezhnaya Irina Yu. , Poberezhny Sergey G. ,   Associate Professor of the Department of Civil Law and Procedure of the Belgorod University of Cooperation, Economics and Law, PhD (Law), Schetkin Dmitry S. ,   Postgraduate Student of the Department of Civil Law and Procedure of the Belgorod University of Cooperation, Economics and Law
Published: June 2024

In this article, the authors analyze the features of the transaction of purchase and sale of residential premises with the participation of a minor citizen as the owner and co-owner.
Andrzeja Dłużniewskiego literatura okruchów codzienności
Authors: Polit Paweł
Published: June 2024

The text is an attempt at discussing the literary dimension of Andrzej Dłużniewski’s artistic output – the way of combining by him the practice of Conceptual art with the construction of literary narratives. Referring to the tradition of ready-made, Dłużniewski used found elements – such as objects, pictures, linguistic expressions – as the carriers of particular stories, whose threads intermesh within a larger structure of references. In his works, the artist linked the visual elements with the linguistic ones, constructed narratives related to objects and pictures. He was the author of concise, sparkling with paradox, literary forms.
A Mendelian Randomization Study on Association of Alpha-synuclein and GPNMB with Parkinson’s Disease Risk and Progression
Authors: Guo Jifeng , Li Lizhi , Liu Zhenhua , Xu Qian , Yan Xinxiang , Tang Beisha
Published: June 2024

The prevalence of Parkinson’s disease (PD) is increasing because of the aging population. Early diagnosis and prognosis of PD remain challenging, suggesting that seeking appropriate biomarkers for PD is crucial. GPNMB and Alpha-synuclein (α-syn) have been reported to contribute to PD pathogenesis and are correlated with PD onset and disease progression. We utilized Mendelian Randomization (MR) analysis to elucidate the association of GPNMB and α-syn with PD and its disease progression. Five MR methods were employed, and inverse variance weighted was chosen as the primary method. The results of MR analysis showed that cerebrospinal fluid (CSF) α-syn correlated with the Unified Parkinson's Disease Rating Scale Ⅲ (UPDRS Ⅲ) and Hoehn and Yahr (H&Y) stage, and plasma α-syn was associated with H&Y stage at baseline suggestively, indicating that α-syn is a promising biomarker for motor symptoms of PD. Overall, CSF and plasma α-syn are potential biomarkers for predicting PD motor symptoms, which warrant further studies. However, no association was detected between GPNMB and PD risk or disease progression.
The effect of the virtual education program on the health responsibility of overweight students during the COVID-19 pandemic
Authors: Dashti Sahar Mahjoub Vagheae , Roshan FatemehSadat SeyedNematollah , AkhavanAmjad Marjan
Published: June 2024

Background: The global prevalence of obesity is increasing not only in adults but also in children and adolescents. In addition to the role of genetic and biological factors, policies such as the need for quarantine during the coronavirus epidemic and the family's behavioral and socioeconomic status in causing obesity cannot be ignored. The current research aimed to investigate the effect of virtual education programs on the health responsibility of overweight students during the outbreak of the Coronavirus.
Methods: The present semi-experimental research was conducted by selecting 60 obese female high school students by random cluster sampling method (case and control) during 2021-22 in Tehran Province, Iran. The virtual training program (6 sessions of 1.5 hours for 6 groups of 5 people) was conducted based on the topics of nutrition, physical activity, sleep, etc. After 1.5 months, students' BMI was measured and a post-test was done. SPSS version 22 software was used for data analysis.
Results: There was no significant change in the BMI of students after the intervention in the control group (p=0.476), but it decreased significantly in the test group (p<0.001). Before the intervention, there was no statistically significant difference between the average score of health responsibility in the test group (54.63 ) and the control group (53.03 6.79) (P=0.370). After the intervention, the mean difference between the test group (62.56) and the control group (55.10) was statistically significant (P<0.001). Before the intervention, about 70% of the students in both the test and control groups were at a relatively favorable health responsibility level. After the study, the number of students in the test group who were placed at a completely favorable level was almost twice as before, and a statistically significant difference was observed between the two groups(P=0.035).
Conclusions: The results of the present study showed that virtual education during the outbreak of COVID-19 has led to an increase in the responsibility for the health of overweight and obese students (in terms of improving health behaviors, increasing the hours of physical activity, and modifying the eating pattern) and reducing the body mass index of students.
Intracorporeal versus extracorporeal neobladder in robot-assisted radical cystectomy: perioperative, oncological, and functional outcomes from a single-institutional experience
Authors: Yan Bing , Liu Yuan , Liu Yang , Zheng Ji , He Peng , Li Xuemei , Li Yuwei , Liu Yuting , Zhou Xiaozhou , Chen Zhiwen
Published: June 2024

Purpose: To compare the perioperative, functional, and oncological outcomes of the intracorporeal neobladder and extracorporeal neobladder (ECNB) technique following robot-assisted radical cystectomy (RARC).
Methods: We reviewed our single-institutional, prospectively collected database for consecutive patients who underwent RARC with an ileum neobladder from July 2016 to February 2023. Patients were divided into 2 groups according to the approach of reconstruction (ICNB or ECNB). The chi-squared test and Wilcoxon test were used to summarize categorical and continuous variables, respectively. survival and complication outcomes were analyzed using Kaplan-Meier curves, multivariate logistic regression and Cox hazards models.
Result: Among 304 patients, 190 ICNB patients and 114 ECNB patients were identified. A shorter median operative time (320 vs. 354 minutes; p = 0.001) and less median EBL (300 vs. 500 ml; p = 0.000) were recorded in the ICNB group. A significant difference in 90-d overall complications was detected between the 2 groups (49.5% vs. 61.4%; p = 0.043). Multivariate logistic regression analysis demonstrated that age, relapsed tumor and surgical approach (ECNB/ICNB) were individual predictive factors for 90-d overall complications. The functional outcomes and survival rates were comparable between the ICNB and ECNB groups. A Cox proportional hazards model indicated that higher pathological stage and pN status are predictors of both recurrence-free survival (RFS) and overall survival (OS).
Conclusion Compared with ECNB, ICNB significantly improved perioperative outcomes without compromising functional or oncological outcomes.
Hypocaloric diet in perinatal life followed by obesity exacerbates metabolic disorders in the offspring of wistar rats
Authors: Araújo Luciana Lima , Do Nascimento Elizabeth , Franco Eryvelton de Souza , Souto Vitória Felício , Melo Maria Claudia Alheiros de Lira , Muniz Gisélia de Santana , Leandro Carol Virgínia Góis
Published: June 2024

The effects of an obesogenic post-weaning diet on the growth and metabolic parameters of adult offspring submitted to a hypocaloric diet in perinatal life were evaluated. Male Wistar rats were divided into two groups according to maternal diet during pregnancy and lactation: Control (C, received normocaloric diet) and hypocaloric diet during pregnancy and lactation (H, received hypocaloric diet). At weaning, half the number of animals in each group was divided into two more groups according to the post-weaning diet: control (CC, n=12), control and subject to the obesogenic diet (CO n=11), hypocaloric diet and control (HC, n=14) and hypocaloric and obesogenic diet (HO, n=9). Maternal body weight, food intake, and energy intake were recorded daily. In the offspring, birth weight, growth rate, and physical characteristics were evaluated. At 120 days, relative food consumption, glucose tolerance test (GTT), biochemical profile, and organ weight were analyzed. Mothers on a low-calorie diet showed no difference in body weight during pregnancy or lactation even with lower energy intake. In offspring, litters from mothers fed a low-calorie diet showed a deficit in physical characteristics (growth restriction and low weight). The effect of an obesogenic diet on visceral fat weight, GTT, and hypercholesterolemia was most pronounced in animals subjected to a perinatal hypocaloric diet followed by a lifelong obesogenic diet. Conclusion: Our observations expand the evidence that social environments with food scarcity and/or obesogenic environments determine greater susceptibility to obesity.
Nanofabrication of Losartan Potassium Sustained Release Floating Microspheres using Different Grades of Ethyl Cellulose and its Insight on Release Profiles
Authors: Rajput Tanavirsing , Mohite Popat , Ghule Santosh , Vinchurkar Kuldeep , Singh Sudarshan
Published: June 2024

Introduction:

A sustained release system for losartan potassium designed to delay its residence
time in the stomach through the preparation of solvent evaporation technique-based floating microspheres.
The influence of the different grades of Ethocel™ such as 4 cps, 10 cps, and 22 cps as well as the drug: polymer
ratio on various properties of microspheres were tested.

Methods:

Thermal and functional analysis revealed no interaction between the encapsulated drug and polymer.
The results indicated that the mean diameter of microspheres increased with a change in grades of ethyl
cellulose relating to viscosity. However, the drug incorporation efficiency within ethyl cellulose microspheres
decreased with increasing viscosity of ethyl cellulose.

Results:

The bulk density of the formulations was proportionally dependent on concentration and the viscosity
of the polymer, which resulted in a decrease in floating capacity from 90.02% to 73.58%. Moreover, the
drug release was indirectly proportional to the viscosity of ethyl cellulose tested. The in vitro release profile
exhibited a burst effect with a biphasic release pattern following Fickian diffusion, indicating a diffusioncontrolled
release mechanism.

Conclusion:

The results demonstrated that the viscosity of ethyl cellulose significantly affects the floating capacity
and drug release pattern from microspheres.
Developments in Organocatalysis Transformations of Unsaturated Pyrazolones
Authors: Doraghi Fatemeh , Gilaninezhad Farzad , Karimian Somaye , Larijani Bagher , Mahdavi Mohammad
Published: June 2024

Unsaturated pyrazolones can participate in organocatalytic reactions with various substrates to form spiro-cyclic pyrazolones, and fuzed-pyrazolone heterocycles. The present review describes progress since 2013 in the organocatalysis transformations of unsaturated pyrazolones. Pyrazolones are prevalent structural motifs in a wide variety of natural products and drug or drug-like molecules. A series of nitrogen-containing pyrazolones exhibits anti-cancer, antimicrobial, anti-inflammatory, anticonvulsant, antidepressant, antidiabetic, and an-tipyretic activities. Especially, chiral spiro-cyclic pyrazolones are recognized as targets in nat-ural products and clinical pharmaceuticals. Organocatalytic systems are powerful and reliable approaches that allow us to build structurally complex molecules in an enantioselectively and diastereoselectively manner. Avoiding the use of transition metal catalysts, readily available bifunctional organocatalysts, and the performance of the reaction at ambient temperature are other advantages of these catalytic systems. Despite considerable progress in this field, it is still one of the challenging goals for chemists to make new biologically active heterocyclic molecules.
Plac Marszałka Józefa Piłsudskiego – trwały element w przestrzeni Warszawy Od dziedzińca pałacowego do otoczenia Soboru, od końca XVIII do początku XX w.
Authors: Wieczorek Anna , Gorzelak Magnolia
Published: June 2024

O warszawskim Placu Marszałka Józefa Piłsudskiego i otaczających go budynkach można przeczytać w wielu książkach i artykułach dotyczących dziejów stolicy oraz historii architektury i urbanistyki. Istnieją również spore zasoby kartograficzne i ikonograficzne w muzeach i archiwach. Analiza materiałów źródłowych wskazuje na duże rozproszenie informacji. Brakuje kompendium wiedzy dotyczącej genezy powstania Placu, zmian w jego wyglądzie i związanej z tym myśli projektowej. Tym zagadnieniom poświęcony jest cykl artykułów pod wspólnym tytułem Plac Marszałka Józefa Piłsudskiego – trwały element w przestrzeni Warszawy. Niniejszy artykuł, drugi w tym cyklu, opowiada jak zmieniał się wygląd Placu od końca XVIII do początku XX w., przekształcając się z Dziedzińca Pałacu Saskiego w otoczenie Soboru. Słowa kluczowe: Plac Marszałka Józefa Piłsudskiego, Pałac Saski, Pałac Brühla, Oś Saska
The Evaluation of a Web-Based Intervention (Deprexis) to Decrease Depression and Restore Functioning in Veterans: Protocol for a Randomized Controlled Trial
Authors: Pearson Rahel , Beevers Christopher G , Mignogna Joseph , Benzer Justin , Pfeiffer Paul N , Post Edward , Creech Suzannah K
Published: June 2024

Background

Depressive symptoms are common in veterans, and the presence of these symptoms increases disability as well as suicidal thoughts and behaviors. However, there is evidence that these symptoms often go untreated. Intervening before symptoms become severe and entrenched is related to better long-term outcomes, including improved functioning and less disease chronicity. Computer-delivered interventions may be especially appropriate for those veterans with mild to moderate depressive symptoms, because these interventions can require fewer resources and have lower barriers to access and thus have potential for wider reach. Despite this potential, there is a dearth of research examining computerized interventions for depressive symptoms in veteran samples.

Objective

The aim of this study is to evaluate the efficacy of Deprexis (GAIA AG), a computerized intervention for depressive symptoms and related functional impairment.

Methods

Veterans will be recruited through the US Department of Veterans Affairs electronic medical record and through primary care and specialty clinics. First, qualitative interviews will be completed with a small subset of veterans (n=16-20) to assess the acceptability of treatment procedures. Next, veterans (n=132) with mild to moderate depressive symptoms will be randomly assigned to the fully automated Deprexis intervention or a treatment-as-usual control group. The primary outcomes will be self-reported depressive symptoms and various dimensions of psychosocial functioning.

Results

This project was funded in May 2024, and data collection will be conducted between October 2024 and April 2029. Overall, 4 participants have been recruited as of the submission of the manuscript, and data analysis is expected in June 2029, with initial results expected in November 2029.

Conclusions

This study will provide initial evidence for the efficacy of self-guided, computerized interventions for depressive symptoms and functional impairment in veterans. If effective, these types of interventions could improve veteran access to low-resource psychosocial treatments.

Trial Registration

ClinicalTrials.gov NCT06217198; https://www.clinicaltrials.gov/study/NCT06217198

International Registered Report Identifier (IRRID)

PRR1-10.2196/59119
СКАНИРУЮЩАЯ КАПИЛЛЯРНАЯ МИКРОСКОПИЯ. ВИЗУАЛИЗАЦИЯ И КОЛИЧЕСТВЕННАЯ ОЦЕНКА
Authors: Ахметова А.И. , Яминский И.В.
Published: June 2024

Исследование морфологии объектов и их механических характеристик позволяет обнаруживать уникальные свойства клеток и связывать эти особенности с развитием в норме или при наличии патологий. Для измерения поверхности образца в сканирующей капиллярной микроскопии (СКМ) в качестве зонда используется заполненный электролитом капилляр с наноразмерным отверстием на кончике. Главным преимуществом СКМ является бесконтактная визуализация топографии биологических объектов в естественной среде – сканирование осуществляется без силового контакта кончика зонда с поверхностью образца. Дополнительно СКМ можно использовать для определения электрических зарядов на границе раздела твердое тело и жидкость. В этой статье мы описываем основы СКМ, возможности метода для визуализации клеток и измерения биомеханических свойств живых образцов.
Assessment of Forced Evaporation as a Solution for Onsite Produced Water Management
Authors: Den Walter , Walla Travis
Published: June 2024

As a net water production entity where unconventional oil and gas
extraction operations generate volumes of hypersaline water (known as
produced water, PW) greater than they consume, it is imperative to
consider what options are available for this new source of water to
displace water demand on the nations already struggling water supplies.
The increased awareness of the adverse environmental impacts associated
with underground injection is expected to drive PW management away from
underground disposal. Meanwhile, the lack of data on the chemical
constituents and the toxicological characteristics of treated PW has
likely hampered regulatory agencies in developing policies that enable
advanced PW treatment for reuse. Therefore, until a PW reuse market
emerges to justify the costs of advanced treatment, the most viable PW
management strategy for operators is to reduce the volume of PW for
disposal. This study examines the cost and environmental benefits of
adopting on-site thermal evaporation process through data collected from
multiple developmental basins – the Rockies, Appalachia, and
Haynesville basins using thermal evaporators. We developed a method for
assessing the cost benefit and applied to a hypothetical scenario for
Eagle Ford shale to demonstrate the potential benefits of thermal
evaporation. The challenges and limitations are also discussed in this
paper.
Casa do Carnaval do Recife
Authors: Silva de Moura Carlos André , Ribeiro dos Santos Mário , Moraes de Araújo Sandra Simone
Published: June 2024

Os espaços de memória e pesquisa são fundamentais na formação das identidades e no reconhecimento de territórios com significados polissêmicos, capazes de preservar modos particulares com os quais os grupos sociais pensam e agem nas diferentes temporalidades. O Centro de Formação, Pesquisa e Memória Cultural, popularmente conhecido como Casa do Carnaval, localizado na área central do Recife, tem contribuído para a salvaguarda e a difusão das culturas populares, muitas vezes negligenciadas por uma “História oficial”. Neste artigo, a partir de visitas e experiências vivenciadas junto a sua equipe gestora, analisamos como esse espaço atua na elaboração de outras histórias e na produção de novos saberes, por meio de exposições das expressões culturais, idealização de materiais bibliográficos e preservação de documentos das mais diversas tipologias, a exemplo da coleção de estandartes que compõe um ambiente impregnado de afetos, histórias e memórias.
Synthesis and in silico ADMET evaluation of new thiazole and thiazolidine-4-one derivatives as non-ulcerogenic analgesic and anti-inflammatory agents
Authors: Nassiri Koopaei , Monavari Mahshid , Vousooghi Nasim , Moshirabadi Sadaf , Assarzadeh Mohammad , Amini Mohsen , Almasirad Ali
Published: June 2024

A series of 1,3-thiazoline-4-one derivatives bearing 2-phenoxyphenyl moiety, were synthesized as potential new analgesic and anti-inflammatory agents. The structures were confirmed by FT-IR, NMR and mass spectra. The abdominal constriction (writing) test was selected to evaluate analgesic activity and the results showed that nearly all of them were active, and the most potent was 10m with 96 % inhibition when compared to the control. The best compounds were selected to investigate the anti-inflammatory activity by carrageenan induced rat paw edema test. The results showed that compounds 8 and 10h were active from the 2nd to 5th hour of assessment. The ulcerogenic evaluation of two selected compounds showed that they are comparable with the vehicle control group and without any ulcerogenic effect potential. The target compounds showed an acceptable in silico ADME profile.
Academic Vocabulary Learning in EMI Classrooms: Challenges and Strategies
Authors: Othman Juliana
Published: June 2024

This study investigates English as a Second Language (ESL) learners’ challenges in understanding academic science vocabulary in Malaysian secondary schools’ English-medium instruction (EMI) classrooms. Based on cognitive load theory, the research explores ESL learners’ strategies to acquire scientific terminology and manage the associated cognitive difficulties. Previous research on EMI across different subjects has often overlooked the specific hurdles presented by technical terms in the scientific vocabulary, creating a knowledge gap that impedes the development of effective teaching methods for science educators in EMI settings. In response, the study adopts a two-stage qualitative design, commencing with an online survey involving 103 participants, followed by group interviews with individuals from diverse linguistic backgrounds. The findings indicate that ESL learners in EMI science classrooms encounter significant obstacles due to unfamiliar scientific terminology, abstract concepts, and limited prior exposure to the subject matter. This results in a high cognitive load that inhibits comprehension. Nevertheless, the research identifies various vocabulary learning strategies students employ, including contextual clues and active engagement with scientific vocabulary within relevant contexts. These findings underscore the need for more inclusive learning environments supporting vocabulary development for ESL learners in EMI settings. Recommendations encompass creating instructional materials featuring clear and concise language and integrating scaffolding strategies to simplify complex scientific terms. This comprehensive approach has the potential to facilitate successful vocabulary development and enhance the overall learning experience for ESL learners in EMI science classrooms.
Malaysian Rural ESL Learners’ Perceived English Language Proficiency
Authors: Muhamad Maizatulliza , Hock Seng Goh , Natchiar Mohd Khaja Farah , Haniff Mohd Tahir Mohd , Saputra Syahwil
Published: June 2024

English is a compulsory subject taught in Malaysian schools, offering opportunities for both personal and career development. Even though the English Proficiency Index Report 2019 indicated that Malaysia is ranked quite highly in terms of English language proficiency, the result does not represent the actual ability among many learners, especially in the rural areas, as Malaysian ESL learners face many difficulties in using English, verbally and in writing. Amidst the debate on Malaysian ESL learners’ proficiency level, it is important to measure how they perceive their ability to use English. This study intends to investigate Malaysian rural ESL learners’ perceptions of their English language proficiency. A survey research design was employed. Two hundred seventy-seven participants of Form 1, Form 3, Form 4, and Form 5 form rural schools in Malaysia who were recruited in this study. The data were gathered from a questionnaire based on the description of the Common European Framework of Reference for Languages (CEFR) ‘Self-assessment grid’. The interview was also conducted to support the quantitative data. The researchers analyzed the percentages, mean scores, and standard deviation of the questionnaire. Content analysis was employed to analyze the data from the interview session. Findings indicate that positive perceptions of English language learning enhance students’ interest, thereby accelerating their proficiency levels. This study offers insight into learners’ perspectives on their English language acquisition journey. Future research might consider employing a larger sample size and additional data collection instruments to enhance the significance of findings, particularly regarding ESL students’ perceptions of their English language proficiency.
Implementation Google Cloud Platform as Data Storage in Industry
Authors: Irawan Achmad Lutfi Helmi
Published: June 2024

As data volumes grow, the need for cost-effective, scalable and secure data storage solutions is more critical than ever. Google Cloud provides various storage solutions such as Cloud Storage, Bigtable, and Firestore that meet industrial needs. This article explores the application of Google Cloud as a data storage solution in an industry. This research uses a case study approach involving in-depth analysis of one or several sectors implementing Google Cloud as a data storage solution with a survey and experimental approach. Our findings show that implementing Google Cloud as a data storage solution can improve data accessibility, management and analysis, decision-making capabilities, and business outcomes.
Diabetic Nephropathy as a Result of Uncontrolled Hyperglycemia
Authors: Aquino Camila Silva de , Miranda Estênio Gabriel , Ribeiro Júnior Francisco José Pascoal , Lucena Hérika Juliana de Araújo , Oliveira Jéssica Pará Amaral de , Lima Neto João Ferreira , Pinho Lênio Airam de , Rodrigues Miguel Valentim , Silvestre Pedro Henrique Borges , Saijo Rafaela de Oliveira Estevão , Bezerra Roberta Fernandes
Published: June 2024

Objective: to investigate the relationship between uncontrolled hyperglycemia and the development of diabetic nephropathy.
 
Methods: Integrative review of the literature, carried out in June 2024, in the virtual databases Virtual Health Library, Medical Literature Analysis and Retrieval System Online and Google Scholar using the descriptors “Diabetic Nephropathies”, “Glomerular Filtration Rate”, “Hyperglycemia” and “Diabetes Mellitus”, as well as “Diabetic Nephropathies”, “Glomerular Filtration Rate”, “Hyperglycemia” and “Diabetes Mellitus” selected by DeCS and MeSH Descriptors, related to the Boolean operator AND in all databases.
 
Results and Discussion: after completing the methodological procedures, 12 articles available on the VHL Portal, in the PubMed, VHL and Google Scholar databases were selected, which show that diabetic nephropathy is a serious and common complication of diabetes mellitus, characterized due to the progressive impairment of renal function, being one of the main causes of chronic kidney disease and terminal renal failure worldwide. The development of diabetic nephropathy is linked to glycemic control, with chronic hyperglycemia being a crucial factor in the pathogenesis of this condition.
 
Final Considerations: strict control of blood glucose and blood pressure, combined with pharmacological interventions and lifestyle modifications, constitutes the basis of effective management of diabetic nephropathy.
Chemical and Mechanical Scarification as Techniques for Overcoming Dormance in Red Tent Seeds (Adenanthera pavonina L.)
Authors: Vieira Cristiane Ramos , Araujo Maicon Marinho Vieira , Souza Marcelo Dias de , Santos Carolina Rafaela Vieira dos
Published: June 2024

Purpose: Evaluate chemical and mechanical scarification techniques, as methods for overcoming dormancy in red vine seeds.
 
Theoretical Framework: Based on scientific articles found on search engines and books in the field of seeds, types of forest seeds, types of dormancy in forest seeds and techniques for overcoming dormancy. In order to support the explanation of how techniques for overcoming dormancy are related to the rate and time of germination of red seed seeds, and how germination time can subsequently affect the quantity of seedlings produced, as well as their initial growth.
 
Method: The experiment was installed to test the following treatments: T0 – without scarification; T1 – mechanical scarification; T2 chemical scarification with 80% H2SO4 for half an hour; T3 – chemical scarification with 80% H2SO4 for one hour; T4 – chemical scarification with 0.4% KNO3 for half an hour; T5 – chemical scarification with 0.4% KNO3 for one hour. The design used was completely randomized, with six treatments, five replications and 20 seeds in each replication. At the end of 30 days, counting from the beginning of germination, the following variables were evaluated: germination speed index (IVG), average germination time (TMG), germination percentage (G) and germination speed index (IVG).
 
Results and Conclusion: The most efficient methods for germinating the red tent seeds were mechanical scarification with sandpaper and immersion in 0.4% KNO3 for half an hour. However, mechanical scarification would be the most easily used and least expensive method for producing seedlings in nurseries.
 
Research Implications: These results indicate that the mechanical scarification technique is an efficient method for overcoming the dormancy of the red tent, which is integumentary. Understanding the most efficient and effective techniques for overcoming dormancy in seeds of species that present this characteristic is important to allow, within the nursery, germination to occur quickly and uniformly. Consequently, making it possible to obtain seedlings with more uniform sizes, even though these are produced from seeds.
 
Originality/Value: A high germination rate and uniform initial growth are important factors within the nursery, especially if it is of a commercial nature, but also for the restoration of areas, because it allows seedlings to be obtained in less time.
EXPLORE THE ROLES OF FEMALE ENTREPRENEURSHIP IN PROMOTING ECONOMIC GROWTH IN ASIA: A PANEL DATA ANALYSIS
Authors: Binh Hoang Xuan , Pham Huong-Giang , Nguyen Khanh Ly T.
Published: June 2024

In Asia, there has been a notable surge in the representation of women in leadership roles and entrepreneurial endeavours, aligning with the increasing acknowledgement of women's importance in politics and the economy. It is predicted that the future development and economic prosperity of Asia will heavily rely on the advancement of female entrepreneurship and empowerment. This research aims to provide empirical evidence on the correlation between female entrepreneurship and economic advancement within the diverse landscape of Asia context, using panel data spanning from 1998 to 2021 across 47 Asian countries. The findings of fixed-effect regression reveal a consistently positive association between women's entrepreneurial activities and economic progress across all Asian economies, encompassing both developed and developing nations. These findings are pivotal for crafting tailored policies aimed at enhancing female participation in entrepreneurship, thereby catalyzing economic growth and advancing towards the most potential in terms of socio-economic conditions.
Las dinámicas geoeconómicas del conflicto entre Rusia y Ucrania en el 2022
Authors: Barrientos Martínez Brandon René
Published: June 2024

El conflicto entre Rusia y Ucrania que inició a principios del año 2022 ha originado toda clase de revisio­nes desde diversos enfoques, a propósito de la diversidad de elementos que componen la guerra como: los derechos humanos; los flujos migratorios; las tensiones diplomáticas; la energía nuclear; el compor­tamiento del dólar, entre otros. En ese sentido, la mirada holística de dicha coyuntura es tan válida como una revisión más específica para comprender las dinámicas del conflicto en cuanto a los resultados y acciones de los actores involucrados, así como los impactos políticos, sociales y económicos.
TRABALHO EXTERNO DO APENADO EM TEMPOS DE PANDEMIA DE COVID-19: GARANTISMO E ATIVISMO JUDICIAL COMO SUSTENTÁCULO DE DECISÕES
Authors: Santiago Nestor Eduardo Araruna , Castelo Branco Connie Francis Andrade
Published: June 2024

O artigo objetiva investigar o motivo da incongruência de dois acórdãos das turmas criminais do Superior Tribunal de Justiça sobre o trabalho externo realizado por apenados em regime semiaberto, durante a pandemia, identificando a natureza das decisões e seus fundamentos teóricos. O texto inicialmente explica sobre a saúde e o trabalho externo dos presos; em seguida, passa a conceituar a teoria do garantismo e o ativismo judicial. Depois aborda os dois acórdãos por meio de suas alegações, percebendo os fundamentos das turmas do Tribunal. A metodologia é documental bibliográfica, com pesquisa de abordagem qualitativa e método dedutivo. Conclui-se que a decisão da sexta turma é garantista, pois baseada na principiologia dos direitos fundamentais normatizada na Constituição; a da quinta turma é ativista, pois não aplica o direito de acordo com a unidade de princípios, com fundamentação meramente formal e incompatível com o Estado Democrático de Direito.
Outcomes of Endovascular Treatment for Salvaging Failed Hemodialysis Arteriovenous Fistula – Role of Balloon Angioplasty as Initial Therapy
Authors: Vignesh S. , Mukuntharajan T. , Sampathkumar Krishnaswamy
Published: June 2024

Background:

This study aims to evaluate the technical and clinical outcomes of endovascular treatment for failed native hemodialysis fistulas, mainly the role of balloon angioplasty in salvaging thrombosed and stenosed arteriovenous fistulas.

Materials and Methods:

This retrospective study was done on 23 patients who had presented with non-functioning dialysis fistulas. The mean age of the patients was 58.7 ± 2.3 years. The cause of failure was thrombosis in 14 cases (61%) and stenosis in 9 cases (39%). All patients initially underwent percutaneous transluminal angioplasty (PTA), followed by thromboaspiration depending on the thrombus load and extent.

Results:

A total of 27 salvage procedures were performed on 23 patients. Technical success was achieved in 24 procedures (88.8%), and clinical success was 81.5%. Patients were followed up for mean duration of 9.5 months (range: 1–19 months). Eight out of 23 accesses initially revised failed again due to repeat thrombosis, of which four patients underwent repeat procedures. The mean duration to re-intervention was 5.5 ± 1.3 months. The primary patency rates were 79% at 3 months and 60% at 6, 12, and 18 months. The cumulative (secondary) patency rates were 73% at 6 months and 66% at 12 and 18 months. Minor complications were seen in three procedures (11%), which included venous extravasation in two cases and prolonged bleeding from puncture site in one case.

Conclusion:

Percutaneous balloon angioplasty can be used as first-line procedure in failed hemodialysis fistulas, in both cases of stenosis and/or thrombosis, followed by thromboaspiration if required.
A POTENCIALIDADE DOS QUINTAIS PRODUTIVOS DA COMUNIDADE SANTO ANTÔNIO, CURRAIS-PI.
Authors: Santos Laésio Luz , Almeida ; Franciele da Silva , Falcão Maria Raimunda Borges , Silva Valcilene Rodrigues da , Souza Sônia Maria Ribeiro de
Published: June 2024

A produção das famílias camponesas exerce acentuado papel na reprodução das comunidades rurais, pois é essa agricultura responsável por boa parte dos alimentos consumidos na cesta básica da classe trabalhadora. Embora as dificuldades enfrentadas sejam muitas, falta de políticas públicas, clima, recursos hídricos, entre outros, comprometendo a produção de alimentos e, muitas vezes, reduzindo a sua produção. O presente relato é resultado do trabalho apresentado na disciplina Organização e Gestão da Produção do Campo, em que no Tempo Comunidade nos foi orientado realizar uma pesquisa sobre um sistema de produção camponesa e, a partir dessas informações, construir um croqui apresentando o que existia no local escolhido para pesquisa.
Por conhecer a comunidade Santo Antônio e os potenciais produtivos ali presentes escolhemos a propriedade de Dona Rosário, mulher, camponesa viúva e que nem por isso deixou de produzir em seu quintal e em grande quantidade, sendo este um dos motivos que tornou a experiência mais relevante.