bluuebunny/crossref_metadata_2025 huggingface dataset:
Making Managing Data Easy-Peasy
Authors:   Universidad Cooperativa de Colombia, Buitrago García Hilda Clarena
Published: March 2023

This class note, made up of three sequenced units, aims at helping both Universidad Cooperativa de Colombia (UCC) teachers and their students to use a variety of tools to find, curate, and manage different kinds of data and references effectively. This will, undoubtedly affect their academic work in a positive way since they can save time and have easier access to more organized and clear information. Whether they teach or take an undergraduate or postgraduate program, this module will increase their efficiency and overall performance. Teachers will be able to help their students navigate databases, necessary for most high-quality academic work, with greater ease. Both conceptual content and practical hands-on activities are provided. This module includes a variety of digital resources, links, tutorials, as well as hands-on and assessment activities. Overall, the quality of education which UCC intends to offer to the whole community can be positively impacted by the content and activities offered in this self-paced and self-managed module.
Paragangliomas, Etiology, Review of 1070 Series of Cases Hospital De Especialidades Centro Médico La Raza
Authors: CS Ficachi-Morales , H Bizueto-Rosas , OA Rodríguez-Jiménez , BD Castro-Luna , GE Guzmán-Rodríguez , PL Díaz-Aguirre , KA Orta-Luna , C Varela-Román , D Medina-Terán , EY Chávez-Vázquez , AA Herrera-Durán , TT Valdés-Gonzalez , AED Luna-Marmolejo , NN Bizueto-Blancas , LM Olivares-Luna , A Velasco-Vázquez , CD Gómez-Calvo
Published: March 2023

Objective: Present the frequency of atypical histological lineage paragangliomas on a third level hospital. Introduction: Paragangliomas, also known as neuroendocrine tumors, are rare and can appear in distinct places throughout the human body where chromaffin cells are present. Such examples include blood vessels and nerves. Thirty percent are in head and neck compartments; after carotid paragangliomas, the yugulotimpanic follow in frequency and then the vagal ones by 5%. Onlyone percent of paragangliomas located in the head and neck are functional compared with those located in other parts of the body that tend to be functional, most commonly causing hypertension. Methods: An ambispective, observational, descriptive review was conducted, including patients operated on by paraganglioma from 1987 to January 2023; 99.4% were initially diagnosed as carotid origin. Results: A total of 1070 patients were captured. 998 patients were female (93.2%). 1,063 of paragangliomas were carotid (99.3%), 2 were vagal (0.18%), 1 was yugulotympanic (0.09%) and 3 were in other locations (0.28%). One was reported as a Schwannoma. None of the tumors were reported as being hyperfunctional. Conclusion: The angiographic visualization of these lesions can confuse their diagnosis and cause an erroneous follow-up with a poor prognosis, since it is described that vagal paragangliomas recur in 17%.
A Study on the Economic Effects of U.S. Export Controls on Semiconductors to China
Authors:   The Korea International Trade Research Institute, Park Do-Joon , Liu Shuzhi
Published: March 2023

Purpose – This study addresses the development of China’s semiconductor industry in the context of the U.S.-China trade conflict, and analyzes the impact on other industries. Design/Methodology/Approach – Based on the multi-regional input-output table industry splitting method, the electrical and electronic equipment manufacturing industry in the Asian Development Bank’s multi-regional input-output table (ADB-MRIO, 2019) is split into semiconductor and non-semiconductor industries, and the impact of U.S. export controls on China’s semiconductor exports on domestic and foreign economies is simulated and analyzed using the hypothesis extraction and hypothesis expansion methods. Findings – The United States has suffered more than China from US export controls on semiconductors to China, and the impact of U.S. export controls on U.S. GDP decreasing by at most 0.0124‰, and China’s GDP decreasing by at most 0.00089‰. Since Japan, Korea, and European countries have become China’s semiconductor import substitutes, they all benefit from U.S. export controls on China. Second, the most affected industries in China are the chemical products, metal products, wholesale, financial, and non-semiconductor industries in the electrical and electronic equipment manufacturing industry. Research Implications – China should adopt coping strategies such as deepening international exchanges, enhancing communication between China and the U.S., and strengthening its scientific and technological strength.
Fostering Organizational Performance at Central and Eastern European Universities: The Impact of Knowledge Creation and Affective Commitment
Authors:   International Burch University, HADZIAHMETOVIC Nereida , DINC Muhammet Sait ,   Indiana University Kokomo
Published: March 2023

The purpose of this study is to examine the impact of knowledge creation and affective commitment on organizational performance. The study also explores the mediating role of affective commitment in this relationship. The results based on the sample of 825 academics and members of the administrative staff at universities from Central and Eastern European countries support the proposed hypotheses of this research. Exploratory and Confirmatory factor analyses were performed to assess the reliability of scales, while structural equation modeling was used to evaluate the hypotheses. This study demonstrates that knowledge creation and affective commitment are predictors of organizational performance. It also shows that affective commitment, which is influenced by knowledge creation, is an important mediating factor that affects organizational performance at public and private universities in Central and Eastern European countries.
Theory of Programming Languages: Design and Implementation
Authors:   Novosibirsk State Technical University, Russian Federation, Shornikov Yury V.
Published: March 2023

The textbook has been prepared in accordance with the State educational Standard in the fields of "Computer Science and Computer Engineering" (09.03.01), "Applied Computer Science" (09.03.03) for the cycle of disciplines of information specialties. The basis of the textbook was the material of lectures delivered by the author to students of the relevant specialties at the Novosibirsk State Technical University and the Kazakh-British Technical University in the courses "Theory of Formal Languages and Compilers", "System Software", and "Linguistic Support". The textbook discusses the theory of generating grammars, finite automata and regular expressions. All theoretical mechanisms of analysis and synthesis of language constructions are strictly formalized and constitute the theoretical foundations of the programming language design. The implementation of programming languages is represented by the development of language processors. The transition from formal languages to language processors is carried out through constructive analysis methods with strict modeling algorithms that can be implemented in high-level languages or with the help of modern programming automation tools. The manual discusses ANTLR and FLEX & BIZON tools for automating parser and lexer programming. Despite the educational orientation, the manual can be useful to anyone who is engaged in the design and implementation of new languages, language processors and finite-automaton recognizers.
СОВРЕМЕННЫЕ ТЕНДЕНЦИИ И ПЕРСПЕКТИВЫ РАЗВИТИЯ ЭКО-ЭТНОТУРИЗМА В ОШСКОЙ ОБЛАСТИ КЫРГЫЗСТАНА
Authors: Сайпидинов Илхам Махамадисаевич , Карбекова Азиза Баймаматовна , Карбекова Мээримай Жумаековна
Published: March 2023

Цель исследования состоит в разработке рекомендаций по развитию эко-этнотуризма в Ошской области Кыргызстана и его перспектив.

Методология. При написании статьи были применены следующие методы: обобщение полученной информации, экономико-статистический анализ, аналитический и сравнительный методы. Методологическую основу и информационную базу исследования составляют статьи, публикации ученых и специалистов в области эко-этнотуризма. В процессе написания статьи используется информация с интернет-сайтов компаний, периодическая литература и книги.

Результаты. На основе зарубежного и отечественного опыта сформулированы предложения и рекомендации, способствующие развитию эко- и этнотуризма с целью развития «зеленых» технологий и снижения нагрузки на экологические аспекты.

Перспективы исследования. Значимость исследования состоит в возможности использования теоретических разработок и результатов исследования при разработке или совершенствовании государственными органами нормативно-правовой базы по развитию эко- и этнотуризма, а также в учебном процессе для подготовки специалистов в области ведения «зеленой» экономики.
ЧЕЛОВЕЧЕСКАЯ ТЕЛЕСНОСТЬ КАК СОЦИОКУЛЬТУРНЫЙ ФЕНОМЕН
Authors: Молоканов Александр Александрович , Пономарев Петр Андреевич
Published: March 2023

Целью исследования является анализ феномена человеческой телесности в контексте социокультурного подхода. Статья исследует категорию телесности как опосредованное социокультурными нормами и ценностными ориентациями сознательное отношение индивида к своему органическому телу.

Методологическую базу исследования представляет дифференциация категорий «физическое тело» человека и «человеческая телесность». На основе интеграции культурологического и психологического подходов человеческая телесность рассматривается как социокультурная категория, связанная с определенными стандартами восприятия человеческого тела в том или ином обществе в определенный период его развития, а также с формирующимися на базе этих социокультурных стандартов индивидуальными образами собственного тела.

Результаты исследования. В понятии телесности выделены три стороны: 1) физические характеристики индивидуального организма; 2) социокультурные представления и нормы, связанные с определением статуса органического тела человека; 3) индивидуальные психологические представления и личное сознательное самопозиционирование индивида по отношению к своему телу. Подчеркивается, что, поскольку телесность является социокультурным по содержанию и личностным по форме самосознанием биологического тела человека, постольку в каждый конкретный исторический период в каждом конкретной социокультурной среде формируются специфические представления и нормы телесности.

Динамизм исторического развития общества неизбежно порождает также динамизм общественных и индивидуальных норм и образов телесности. Кризисные периоды в развитии общества порождают противоречивые, проблематические социокультурные образы и образцы телесности и деформируют, дезориентируют личное, индивидуальное самосознание телесности.

Перспективы исследования заключаются в содержательном анализе качественных трансформаций социокультурных и индивидуальных форм телесности в современном российском обществе в контексте проблемы преемственности, соотношения прерывности и непрерывности в динамике форм телесности в рамках истории данного социокультурного субъекта.
A Systematic Literature Review of the Phenomenon of Disinformation and Misinformation
Authors: Pérez-Escolar Marta , Lilleker Darren , Tapia-Frade Alejandro
Published: March 2023

Disinformation threatens the virtue of knowledge. The notion of truth becomes corrupted when citizens believe and give credibility to false, inaccurate, or misleading messages. This situation is particularly relevant in the digital age, where users of media platforms are exposed to different sorts of persuasive statements with uncertain origins and a lack of authenticity. How does academia understand the disinformation problem, and are we equipped to offer solutions? In response to this question, our study provides an overview of the general definitions, trends, patterns, and developments that represent the research on disinformation and misinformation. We conducted a systematic review of N = 756 publications covering eight years, 2014–2022. This period captures phenomena such as Trump’s emergence as a candidate for the US presidency, his term in office, as well as the leadership of figures such as Erdogan in Turkey, Bolsonaro in Brazil, Modi in India, and various similar populist and nationalist leaders across a range of democratic and semi-democratic societies. This period is also one that witnessed the first global pandemic, when misinformation and disinformation not only threatened societal cohesion but the lives of people. This systematic review explores the critical terminology used, the areas of social life where disinformation is identified as problematic, the sources identified as creating or circulating this material, as well as the channels studied, the targets, and the persuasiveness of the discourse. What this article offers, then, is an overview of what we know about disinformation and what gaps in research should be pursued. We conclude that given the problems that misinformation and disinformation are seen to cause for democratic societies, we need to assess the contribution of social science in providing a foundation for scientific knowledge.
U-PB GEOCHRONOLOGY OF CRYSTALLINE ROCKS OF VILSHAN MINE (MIDDLE BUG, UKRAINIAN SHIELD)
Authors:   M.P.Semenenko Institute of Geochemistry, Mineralogy and Ore Formation NAS of Ukraine, Stepaniuk L. , Zagnitko V. ,   Taras Shevchenko National University of Kyiv, Ukraine, Dovbush T. ,   M.P.Semenenko Institute of Geochemistry, Mineralogy and Ore Formation NAS of Ukraine, Kovalenko N. ,   M.P.Semenenko Institute of Geochemistry, Mineralogy and Ore Formation NAS of Ukraine, Zülzle O. ,   M.P.Semenenko Institute of Geochemistry, Mineralogy and Ore Formation NAS of Ukraine, Yaskevych T. ,   M.P.Semenenko Institute of Geochemistry, Mineralogy and Ore Formation NAS of Ukraine
Published: March 2023

Geochronological studies of granitoids from the Vilshansky mine of Middle Pobuzhzhya were carried out. Zircons and monacites from plagiogneiss, plagiogranites and migmatites of the Bug complex were analyzed. As a result, it was established that the rock association, which consists of migmatites with numerous xenolites of biotite gneisses, plagiogneises, occasionally graphite-containing gneisses, amphibolites and biotites (Khashchuvate-zavalivska suite of the Bug series) and intersected with the veins of aplito-pegmatoid granites, was formed as a result of a large-scale manifestation of graniteization processes, which began not later than 2.02 billion years ago and ended about 2.0 billion years ago. The age of metamorphic host rocks corresponds to the Archean values of uranium-lead dating.
Hydrodynamic Force of Resistance of Tourist Underwater Vehicle’s Bare Hull with Diff erent Heads using OpenFOAM
Authors:   University of Zagreb, Faculty of Mechanical Engineering and Naval Architecture, Croatia Hakim Sabzevari University, Department of Civil Engineering, Sabzevar, Iran, Saghi Hassan , Parunov Joško
Published: March 2023

Power reduction is the central goal to maximize cruising duration of tourist underwater vehicles (UV) that can be achieved by shaping the hull. So, in this paper, hydrodynamic force of resistance of the tourist UV’s bare hull is analysed. A numerical model based on Computational Fluid Dynamics in OpenFOAM is developed to simulate the longitudinal movement of an UV in a viscous and incompressible fluid for the infinite water depth. Three head geometries, including both spherical heads (S-S), spherical bow and elliptical stern head (S-E), and UV with both elliptical heads (E-E) are compared. At the first step, the effects of the length-to-diameter ratio and forward speed is studied for the S-S UV. The mesh size is calibrated using Grid Convergence Index, provided by ASME, while the model validation is based on the results for cube and sphere as well as by comparison with resistance coefficient of a SUBOFF bare hull. S-E and E-E UVs are then analysed for typical length-to-diameter ratio, comparing their force of resistance to the S-S type. The elongated elliptical heads are in many cases found favourable compared to the spherical heads. The results of this study may be useful for the conceptual design of tourist UV and for verification of the complex numerical models that are necessary to account for the influence of appendages on the force of resistance of such innovative UV.
Human Character Based on Ki Ageng Suryomentaram Teachings and Its Implementation in Guidance and Counseling Services
Authors: Habsy Bakhrudin All , Kurniawan Nanda Alfan
Published: March 2023

Abstract: The Indonesian nation as a large nation consisting of various religions, ethnicities, and cultures, of course, deserves to have the aspiration to have a basic human philosophy paradigm based on Indonesian culture based on dialogue between the soul sciences that live in Indonesian human cognition. This study aims to present the concept of basic human philosophy in the teachings of Ki Ageng Suryomentaram. The research method uses Gadamerian hermeneutics in a qualitative approach. The collected data is then analyzed using Parts and Whole analysis and then checked the validity of the data through the stages of credibility, transferability, dependability, and confirmability. The results of the study describe human philosophy based on basic needs, essence, existence, and the structure of the human personality. The conclusion of the research refers to the basic human philosophy based on local wisdom for the science of guidance and counseling.
Abstrak: Bangsa Indonesia sebagai bangsa besar yang terdiri dari berbagai macam agama, suku dan budaya, tentunya layak jika memiliki cita-cita memiliki paradigma filsafat dasar manusia berbasis budaya khas Indonesia dengan berlandasakan dialog antara ilmu-ilmu jiwa yang hidup dalam kognisi manusia Indonesia. Penelitian ini bertujuan menyajikan konsep filsafat dasar manusia dalam ajaran Ki Ageng Suryomentaram. Metode penelitian menggunakan hermeneutika Gadamerian dalam pendekatan kualitatif. Data yang telah terkumpul dianalisis menggunakan analisis Parts and Whole dan selanjutnya dicek keabsahan datanya melalui tahapan kredibilitas, transferabilitas, dependabilitas dan konfirmabilitas. Hasil penelitian menjabarkan filsafat manusia berdasarkan kebutuhan dasar, esensi, eksistensi, dan struktur kepribadian manusia. Kesimpualan penelitian mereferensikan filsafat dasar manusia berbasis kearifan lokal untuk ilmu bimbingan dan konseling.
Construction of Tudang Sipulung as A Group Counseling Strategy for Bugis Adolescents in The Perspective of KIPAS Counseling Model
Authors: Aswar Aswar , Nur Edil Wijaya , Amirullah M. , Fitriana Fitriana
Published: March 2023

Abstract: The purpose of this article is to describe the existence of Tudang Sipulung for group guidance that used KIPAS Counseling for the Bugis Youth at Senior High School at Sidrap. This research used a qualitative approach with Triple Hermeneutic Analysis method. The data collection technique are Interview and literature studies as well as data validation which is achieved through data triangulation. The subjects of this study were four people, two people from public figure (culturalists) and two people from students (Bugis youth). The results showed that Tudang Sipulung is the ancestral heritage of the Sidrap’s Bugis Society which contains positive values in the deliberation to reach consensus. In the practice of guidance and counseling, Tudang Sipulung can be constructed and implemented as group guidance in the perspective of the KIPAS counseling model in serving the counselee or Bugis Youth. The cultural values of Tudang Sipulung that can be integrated with the KIPAS model counseling include the counselor’s self-positioning, discussion themes, attitude, and positive thinking techniques, as well as the special technique of KIPAS is KaDo-MUDAH, and up to the steps of the KIPAS Counseling model
Abstrak: Kajian ini berupaya untuk mendeskripsikan eksistensi Tudang Sipulung sebagai sarana bimbingan kelompok dalam kerangka acuan konseling model KIPAS (Konseling Intensif dan Progresif yang Adaptif terhadap Struktur) terhadap Remaja Bugis sekolah menengah atas di Kab. Sidenreng Rappang. Metode penelitian yang digunakan adalah kajian AHB (analisis hermeneutika bersusun). Pengumpulan data dilakukan melalui wawancara dan studi kepustakaan, serta pengabsahan data ditempuh melalui triangulasi data. Pada penelitian ini, subjek berjumlah 4 orang, 2 orang dari kalangan tokoh masyarakat (budayawan) dan 2 orang dari kalangan siswa (remaja Bugis). Hasil penelitian menunjukkan bahwa Tudang Sipulung merupakan warisan tradisi leluhur masyarakat Bugis Sidenreng Rappang (Sidrap) yang mengandung nilai-nilai positif dalam bentuk wahana kelompok ketika hendak membicarakan suatu hal yang perlu untuk disepakati secara bersama-sama. Pada praksis bimbingan dan konseling, Tudang Sipulung dapat dikonstruksi dan diimplementasikan sebagai strategi bimbingan kelompok dalam perspektif konseling model KIPAS dalam melayani konseli atau remaja yang berlatar suku Bugis. Adapun nilai-nilai budaya Tudang Sipulung yang dapat diintegrasikan dengan konseling model KIPAS meliputi pemosisian diri konselor, tema bahasan, teknik-teknik bersikap dan berpikir positif serta teknik khusus KaDo-MUDAH, hingga langkah-langkah konseling model KIPAS.
Real-Life Problems to Increase the Critical Analysis Thinking Among Novice Counselors in Humanistic Counseling Courses: Is It Effective?
Authors: Irani Luthfita Cahya , Suwarjo Suwarjo , Nhung Le Ngoc Ai
Published: March 2023

Abstract: This study aims to determine the effectiveness of using real-life problems to improve novice counsellors' critical analytical thinking in humanistic counselling courses. The research method uses an experiment with a pretest-posttest control group design. The instrument used is a critical-analytical thinking scale. The research sample used a purposive sampling technique, which consisted of 84 students of the 2018 Guidance and Counseling UNY Study Program who took the Humanistic Counseling course. The samples were separated into experimental and control groups of 42 students. The pre-test and post-test data were analyzed using an independent sample t-test using SPSS Amos 25 software. The results show that the use of real-life problems in the Humanistic Counseling course was proven effective in improving students' critical-analytical thinking as novice counsellors. As a result, students are more stimulated to practice analyzing cases in various ways and can activate their cognitive complexity processes as novice counsellors.

Abstrak: Penelitian ini bertujuan untuk mengetahui keefektifan penggunaan masalah hidup riil untuk meningkatkan pemikiran kritis-analitis calon konselor pada mata kuliah konseling humanistik. Metode penelitian yang digunakna ialah eksperimen dengan rancangan pretest-posttest control group design. Instrumen yang digunakan ialah skala berpikir kritis-analitis. Sampel penelitian menggunakan teknik purposive sampling, yakni terdiri dari 84 mahasiswa angkatan 2018 porgram studi Bimbingan dan Konseling Universitas Negeri Yogyakarta yang menempuh mata kuliah Konseling Humanistik. Sampel dipisah pada kelompok eksperimen dan kelompok kontrol yang masing-masing berjumlah 42 mahasiswa. Data pre-test dan post-test dianalisis menggunakan independent sample t-test dengan menggunakan software SPSS Amos 25. Hasil penelitian menunjukkan bahwa, penggunaan masalah hidup riil pada mata kuliah konseling humanistik terbukti efektif meningkatkan pemikiran kritis-analitis mahasiswa calon konselor. Mahasiswa lebih terstimulasi untuk berlatih menganalisis kasus secara beragam serta mampu mengaktivasi proses kompleksitas kognitifnya sebagai calon konselor.
Pengembangan LKPD Interaktif Berbasis Swishmax Materi Narasi Kelas V SD
Authors: Kautama Elsa Dwi , Sutansi Sutansi , Muzaki Ferril Irham
Published: March 2023

Abstract: This study aims to develop interactive worksheets based on Swishmax class V narrative materials that are suitable for use as teaching materials for Indonesian language content. This research is a Research and Development research that uses the ADDIE development model. The techniques used for data collection in the study were interviews, questionnaires, and documentation. The feasibility of the product can be seen from the validation results by material experts, media experts, and teachers and students as users. Material and media validation each obtained 91.67 percent results with a very valid category. While the user practicality test obtained 97.92 percent results in the very practical category. And very interesting with 100 percent results obtained from the attractiveness test by students. So it can be concluded that the LKPD based on Swishmax class V narrative material is feasible to use without revision in the implementation of learning.

Abstrak: Penelitian ini bertujuan untuk mengembangkan LKPD interaktif berbasis Swishmax materi narasi kelas V yang layak digunakan sebagai bahan ajar muatan Bahasa Indonesia. Penelitian ini merupakan penelitian Research and Development yang menggunakan model pengembangan ADDIE. Teknik yang digunakan untuk pengumpulan data dalam penelitian adalah wawancara, angket, dan dokumentasi. Kelayakan produk dapat diketahui dari hasil validasi oleh ahli materi, ahli media, dan guru serta peserta didik sebagai pengguna. Validasi materi dan media masing-masing memperoleh hasil 91,67 persen dengan kategori sangat valid. Sedangkan uji kepraktisan pengguna memperoleh hasil 97,92 persen dengan kategori sangat praktis. Dan sangat menarik dengan hasil 100 persen diperoleh dari uji kemenarikan oleh peserta didik. Sehingga dapat disimpulkan bahwa LKPD berbasis Swishmax materi narasi kelas V layak digunakan tanpa revisi dalam pelaksanaan pembelajaran.
Pengembangan Media Maket pada Materi Peninggalan Sejarah Hindu, Budha dan Islam, Kelas IV Sekolah Dasar
Authors: Raharjo Mohammad Sofwan , Murti Tri , Cholifah Puri Selfi
Published: March 2023

Abstract: Learning in elementary schools requires appropriate media to facilitate teachers and students in achieving learning objectives. The purpose of this research is to produce social studies learning media products in the form of mockups on historical relics of Hindu, Buddhist and Islamic grade IV Elementary Schools that are valid according to media experts, material experts and users (teachers) and are interesting for students. In this type of research Research and Development using the ADDIE model and through 5 stages, namely Analysis, Design, Development, Implementation and Evaluation. The results obtained from the validation of material experts are 91.6 percent, media experts are 81.25 percent, user 1 is 90 percent and user 2 is 95 percent. The test results of the attractiveness of the small group students were obtained at 92.59 percent and the large group obtained the results of 95.47 percent. From these results, if accumulated, the results can be used without revision and the media is interesting for students.

Abstrak: Pembelajaran disekolah dasar memerlukan media yang tepat guna untuk memudahkan guru dan siswa dalam mencapai tujuan pembelajaran. Tujuan dari penelitian ini untuk menghasilkan produk media pembelajaran IPS berbentuk Maket pada materi peninggalan sejarah Hindu, Budha dan Islam kelas IV Sekolah Dasar yang valid menurut ahli media, ahli materi dan pengguna (guru) serta menarik bagi siswa. Pada penelitian ini berjenis Research and Development dengan menggunakan model ADDIE dan melalui 5 tahapan yaitu Analysis, Design, Development, Implementation dan Evaluation. Hasil yang diperoleh dari validasi ahli materi sebesar 91,6 persen, ahli media sebesar 81,25 persen, pengguna 1 sebesar 90 persen dan pengguna 2 sebesar 95 persen. Hasil uji coba kemenarikan siswa kelompok kecil diperoleh sebesar 92,59 persen dan kelompok besar diperoleh hasil sebesar 95,47 persen. Dari hasil tersebut jika diakumulasikan mendapat hasil dengan katergori dapat digunakan tanpa revisi dan media menarik bagi siswa.
Favorable response of hepatocellular carcinoma with portal vein tumor thrombosis after radiotherapy combined with atezolizumab plus bevacizumab
Authors: Kim Yong Tae , Kim Jina , Seong Jinsil
Published: March 2023

Recently, the superiority of atezolizumab plus bevacizumab (AteBeva) over sorafenib was proven in the IMbrave150 trial, and AteBeva became the first-line systemic treatment for untreated, unresectable hepatocellular carcinoma (HCC). While the results are encouraging, more than half of patients with advanced HCC are still being treated in a palliative setting. Radiotherapy (RT) is known to induce immunogenic effects that may enhance the therapeutic efficacy of immune checkpoint inhibitors. Herein, we report the case of a patient with advanced HCC with massive portal vein tumor thrombosis treated with a combination of RT and AteBeva, who showed near complete response in tumor thrombosis and favorable response to HCC. Although this is a rare case, it shows the importance of reducing the tumor burden via RT to combination immunotherapy in patients with advanced HCC.
A Line Fitting Algorithm: Linear Fitting on Locally Deflection (LFLD)
Authors: Yasak Mahmut Sami , Bilgehan Muhammed Said
Published: March 2023

The main motivation of the study is to prevent and optimize the deviations in linear connections with complex calculations related to the previous and next steps. This purpose is used for more stable detection and therefore segmentation of object edge/corner regions in Quality Control Systems with Image Processing and Artificial Intelligence algorithms produced by authors within Alpplas Industrial Investments Inc. The dataset used in this area was originally obtained as a result of the edge approaches of the plastic panels manufactured by Alpplas Inc., extracted from the images taken from the AlpVision Quality Control Machine patented with this research. The data consists entirely of the pixel values of the edge points. Dispersed numeric data sets have quite changeable values, create high complexity and require the computation of formidable correlation. In this study, dispersed numeric data optimized by fitting to linearity. The LFLD (Linear Fitting on Locally Deflection) algorithm developed to solve the problem of linear fitting. Dispersed numeric data can be regulated and could be rendered linearly which is curved line smoothing, or line fitting by desired tolerance values. The LFLD algorithm organizes the data by creating a regular linear line (fitting) from the complex data according to the desired tolerance values.
Performance analysis in a two-phase interleaved DC-DC boost converter with coupled inductors
Authors: Balcı Selami , Sabancı Kadir
Published: March 2023

In this study, the inductor current ripple and output voltage ripple of a two-phase DC-DC boost converter, circuit performance is investigated according to the direct/inverse coupling effect of the coupled inductors. The coupled inductors are modeled with both power electronics circuit and electromagnetic modeling and by using finite element analysis software (FEA). However, the high frequency inductor designs generally use air-gapped composite ceramic ferrite cores and are designed with powder core (Kool Mu) core structures that eliminate air gap requirements. Thus, the fringe flux, which occurs in the air gaps in ferrite cores and reduces the useful flux, and the bad effects such as overheating and electromagnetic noises (EMI/EMC) in the air gaps in high frequency switching are also reduced. Especially in interleaved power converter designs, the performances of coupled inductors affect the output parameters of the power electronics circuit. Considering energy efficiency and more compact circuit topologies, the modeling and simulation approach of high-frequency inductors using finite element analysis software, which is emphasized in this study, popularly and scientifically guides power electronics circuit designers.
The relevance of Takotsubo cardiomyopathy as a stress-induced disease
Authors: Ganych A.A. , Oflidi E.K. , Zaitseva A.Y. , Myasnikova A.B. , Chernik O.V.
Published: March 2023

Takotsubo cardiomyopathy, or Takotsubo syndrome, can be quite rare found, but however the frequency of diagnosing with this disease among patients of cardiology departments is constantly growing. On the one hand, this may be due to improved diagnostics of this pathology, and on the other hand, to an increasing frequency of mental disorders in the human population and the spread of other risk factors, including drug-induced variants. The pathogenesis of the development of Takotsubo cardiomyopathy is associated with an increase in the level of catecholamines, which may be the result of a reactive sympathetic enhancement in response to external factors or be the result of taking antidepressants that can produce a similar effect. Although the diagnostics of this pathology has made significant progress, but however there is still no consensus on the strategy of treatment. This is due to the lack of large-scale randomized prospective studies that could justify one or another therapeutic approach. Basically, the efforts of medical doctors are aimed at maintaining cardiac activity, eliminating the trigger of the disease and at treating complications. The purpose of this review was to summarize the accumulated information related to the problems of etiology, pathogenesis, diagnosis and treatment of Takotsubo cardiomyopathy with an emphasis on the variants associated with the use of antidepressants.
Effect of Light Emitting Diode and TiO2-decorated Ag Nanoparticles on Skin Cancer A431 Cell Line
Authors: Dheaa D.J. , Mahdi S.A.
Published: March 2023

Background: Devices based on light-emitting diodes (LEDs) are the newest and safest method for treating a variety of ailments, and dermatologists are now routinely using them. To confirm the effectiveness of this type of treatment, more controlled research are still required. Materials and Methods: A431 Cell line and treatment with blue LED at output light wave intensity 1200-1400 mw/cm. photodynamic therapy (PDT) with TiO2/Ag using human skin cancer cells as experimental model were used. Cell death and a possible mechanism of action were studied. Results: Blue light (wavelength 420–480 nm) exposure caused a rapid and significant decline in viability, which was followed by the death of over half of the cells. The current paper reviews the state of the art in skin LED-based treatment methods. The newest and safest treatment is LED therapy with nanoparticle, the treatment of radioactively irradiated cells with LED causes an increase in cell death. Blue light exposure might open up new possibilities for treating superficial skin cancers in people. Conclusion: The blue light (420–480 nm) of the light-emitting diode had a better anticancer effect on the SCC cell line after 24 hours of incubation. The best results were obtained with a 240-second exposure time in light with a TiO2/Ag concentration of 400 µg/ml.
In Silico study on Targeting Human C-Reactive Protein Involved in Cardiovascular Disease using Quercetin
Authors: Upadhyaya P. , Joshi A. , Dongre S.
Published: March 2023

Cardiovascular disease is one of the leading causes of death and disability in humans. Quercetin (Que) and its analogs are found in plants naturally and have been shown to have promising bioactive effects. The relationship between “Human C-reactive protein (CRP)” and the cardiovascular system (CVD) has been extensively researched over the last several decades. Numerous studies have looked at Que's potential benefits for a wide variety of medical conditions, including diabetes, inflammation, microbial infection, arthritis, heart disease, and wound healing. In current study the binding affinity of Quercetin against the cardiovascular target protein was analyzed using molecular docking because of the significance of protein-ligand interactions in structure-based drug development. After downloading the CRP (Target Cardiovascular Protein) 3D structure from Protein Data Bank, the authors used the Autodock software to position it in its docking environment and it was reported that the binding energy of Quercetin molecule with CRP is -6.28 kcal/mol. Though more in-vitro studies are required to validate this research. The findings suggest that Quercetin may protect against cardiovascular disease and cancer.
A Computational Study of Tissue Plasminogen Activator (Tpa) and Vanillylamine for Treatment of Heart Stroke
Authors: Jayanand . , Goswami T. , Shrivastava P.
Published: March 2023

When blood cannot flow to the brain, a stroke occurs. A blockage or burst blood vessel inside the brain is a common culprit for this disturbance in blood flow because they both limit oxygen to the brain tissue. If this happens, the brain's oxygen-starved cells begin to die quickly, so it's important to get medical attention at once for the patient's chances of recovery. The major objective of this study is to investigate potent thrombolytics from natural sources that are used to treat stroke. Natural sources have been found to exhibit thrombolytic action, with active molecules also extracted and described. The ligand strength was confirmed in the present work using the binding energy, which is based on computer-aided molecular modeling. Vanillylamine exhibited a stronger docking score and had greater thrombolytic potency than other drugs. The main objective of this study is to find an effective treatment for heart attacks. The protein and ligand combination had an affinity of -5.40 kcal/mol, which further suggests that it may be employed in future studies to create a potential inhibitor against stroke.
Computational Docking Studies of MAPK1 Target Protein Responsible for Heart Failure Using Catechin as Natural Inhibitor
Authors: Malathi H. , Singhal A. , Goyal J.
Published: March 2023

Mitogen-activated protein kinases (MAPKs) are major thespians that have been the subject of in-depth research over the last few decades among the several intracellular signaling networks that regulate the pathophysiology and development of the heart. Heart failure is one of the most common reasons for hospitalization and is a serious public health issue. Heart failure mostly affects the elderly, and as life expectancy increases and chronic medical conditions are better managed, more people are expected to develop the condition. The thrust to investigate alternative traditional medicine has attracted much attention as there are many negative effects of the current pharmacological treatments that are being used to control the problem of heart failure. The protein's original configuration and the ligand combination both had binding energies of -5.62 kcal/mol, which may pave the way for future use of the knowledge about the responsible protein and optimization of their lead molecule for an alternative treatment for the cases of heart failure. But further research is needed, for the validation of the data in wet labs, larger trials and in-vitro studies, to establish its drug-likeliness and their applications.
Design and implementation of diabetic retinopathy detections on retinal images
Authors: Birunda M. , Saravanan N. , Selvi C. , Ramya S. , Thirishiya L. , Selvabharathi K.
Published: March 2023

A retinal picture gives a depiction of what's going on inside the human body. Specifically, the condition of the retinal vessels has been appeared to mirror the cardiovascular state of the body. Retinal pictures give impressive data on neurotic changes brought about by neighbourhood visual illness which uncovers diabetes, hypertension, arteriosclerosis, cardiovascular infection and stroke. PC supported examination of retinal picture assumes a focal part in indicative methodology. Nonetheless, programmed retinal division is muddled by the way that retinal pictures are frequently uproarious, inadequately differentiated, and the vessel widths can shift from enormous to exceptionally little. So in this venture, we can carry out robotize division approach dependent on diagram hypothetical strategy to give local data utilizing measure. We address the portioned vascular construction as a vessel fragment diagram and make the issue of recognize vessels as one of discovering the veins in the chart given a bunch of requirements like CRAE and CRVE. These estimations are found to have great connection with hypertension, coronary illness, and stroke. Be that as it may, they require the precise extraction of particular vessels from a retinal picture. We plan a strategy to tackle this improvement issue and assess it on an enormous genuine world dataset of retinal pictures.
A Study to Assess the Effectiveness of Mindfullness Based Guided Meditation Therapy to Reduce the Level of Anxietyamong Alcohol Dependent at Sree Balaji Medical College and Hospital, Chennai
Authors: Nirmala N. , Hemavathy V.
Published: March 2023

Alcoholism is a serious health concern. Anxiety is a side effect of alcoholism that adds to the burden of sickness caused by alcohol. Anxiety disorders and alcoholism co-occur often and are addressed with a complicated and dynamic presentation.This study focusing on mindfulness guided meditation treatment for reducing anxiety levels among alcohol addicts. .It is an experimental study conducted at Sree Balaji Medical College Hospital in the deaddiction unit among patients of alcohol dependent. The samples been selected by purposive sampling method. The total population selected was 30, and was divided in to two groups.Control and experimental group. Study participants groupedaccording the criteria for selection. Data collected for demographic variable by questioners method. Mindfulness based Guided meditation therapy taught by recorded audio and the pre and post level of anxiety assessed by standardised tool of Hamilton anxiety scale. According to the analysis the guided meditation treatment reduced the anxiety level in experimental group, Shows mindfulness guided meditation therapy has been found to be an effective treatment.
A Study to Assess the Functional Independance and Disability Evaluvation Among Stroke Patients
Authors: Deepen M. , Karpagam K. , Barathi K.S.
Published: March 2023

Introduction: Stroke is medically called cerebrovascular accident (CVA) that's described as a surprising lack of feature due to harm to the brain (hemorrhagic stroke) and absence of blood deliver to the brain (ischemic stroke) reasons weak spot of muscle specifically on one aspect of the body, confusion, trouble in speaking, visible disturbances, trouble in walking, surprising intense headache which ends up in long time disability. The World Health Organization has currently proposed a brand new International Classification of Functioning, Disability and Health that defines additives of functioning and disability, in addition to sports and participation. The latter thing describes nine domain names of interest and participation: getting to know and making use of knowledge; widespread responsibilities and demands; communication; mobility; self-care; home lifestyles; interpersonal interplay and relationships; main lifestyles areas; and community, social, and civic lifestyles. Although scientific trials of stroke interventions robotically use mortality as an outcome, different results are each essential for scientific investigations and applicable to patients.Methods:A descriptive research design was adopted for the study. (n=60 )Samples patients with stroke whowere met the inclusion criteria is selected by using convenience sampling technique. After selecting the sample, the investigator introduced him-self and explained the purpose of the study to the participants’. Informed consent was obtained from the patients relatives after assured confidentiality. The Demographic and clinical variables were collected by using multiple choice questionnaires. The functional independence and disability assessing by using Barthel Index and Modified Ranking Scale. The score is monitored on the day of data collection. Each score evaluation will take 10 minutes. The data were tabulated and analyzed by descriptive and inferential statistics. Results: The level of functional independence among stroke patients study finding shows that out of 60 samples in level of functional independence by using Barthel index, 22(36.7%) were severely dependent, 20(33.3%) were moderately dependent, 11918.3%) were slightly dependent and 7(11.7%) were totally dependent and level of disability among stroke patients study finding despite that out of 60 samples, 22(36.7%) had moderately severe disability, 14(23.3%) had moderate disability, 11(18.3%) had slight disability, 10(16.7%) had severe disability and 3(5%) had no significant disability. Conclusion:A Barthel index and Modified Ranking Scale was effective scale to assessing the functional independence and disability among stroke patients.
Indonesian EFL Teachers’ Perceptions on Flipped Classroom Approach in Modern Classroom Contexts
Authors: Wijaya Kristian Florensio
Published: March 2023

One of the notable shifts EFL educationalists have to incorporate to promote more holistic language learning outcomes is the learner-oriented approach. With this background issue in mind, flipped classroom approach is rewarding to be integrated with nowadays classroom contexts since second language learners are more capable of becoming more proactive, responsible, and well-organized learning community members. This case study was conducted to generate richer and more robust research results out of the specific research phenomenon. The main purpose of this case study is to reveal the importance of integrating flipped classroom approach in modern classroom contexts to Indonesian EFL educators. To fulfill this study objective, two experienced Indonesian EFL teachers were invited to share their experiences in utilizing flipped classroom approach by filling out five open-ended written narrative inquiry questions through the WhatsApp application. Regarding the obtained research results, there were two major specific themes namely: (1) The effectiveness of flipped classroom approach depends on learners’ learning eagerness and (2). Flipped classroom approach progressively promotes more fruitful learning outcomes. Based on these two themes, it can be fairly inferred that the constant internalization of flipped classroom approach can promote a significant degree of benefits for EFL learners’ target language learning proficiency, motivation, and independence.