bluuebunny/crossref_metadata_2025 huggingface dataset:
Six Steps Toward Improving Discoverability of Ph.D. Dissertations
Authors:   University of Novi Sad, Paskali Ljubomir , Ivanović Lidija ,   University of Novi Sad
Published: February 2022

This study proposes six steps that scientific institutions should undertake to increase the visibility and accessibility of their dissertations; these steps were implemented in the digital library of the University of Novi Sad. An analysis was conducted thereafter to evaluate the success, and it was found that the six steps and associated strategies were successful, with 400,000 downloads having been performed since the digital library was operational. Although this study presents six steps for improving electronic thesis and dissertation (ETD) discoverability in the digital library at the University of Novi Sad, these steps can easily be customized and implemented for ETD digital libraries at any scientific institution.
Digital Preservation, Accessibility, and Use of Electronic Theses and Dissertations in University Libraries in Nigeria
Authors:   Federal University of Technology, Minna, Saka Katamba Abubakar , Yusufu Abu ,   Ahmadu Bello University, Zaria, Mommoh Rose
Published: February 2022

This study examined the concepts and aspects of digitization; digital preservation; digital resources; and access to, use of, and challenges posed by electronic theses and dissertations (ETDs) in university libraries in six geopolitical zones of Nigeria. It adopted a documentary research approach to highlight a critical examination of the various aspects of digitization (to provide electronic information services) as practiced by various university libraries and some library schools in Nigeria. Print theses and dissertations (T/Ds) are digitized by document scanning or direct text input (alphanumeric characters) into computer systems. Digital resources include e-books, e-journals, ETDs, and other forms of documents in electronic formats. ETDs are preserved through digitization, archiving, and creation of websites and databases as well as through floating institutional digital repositories (IDRs). ETD access is facilitated by tools such as automated library catalogs and classification schemes, online public access catalog, indexes, abstracts, bibliographies, and mobile devices such as smartphones and personal computers. ETDs are capable of meeting research and publication needs of teaching, information service delivery, and knowledge sharing. Challenges to digital preservation, access, and use of ETDs include inadequate information and communications technology (ICT) facilities, low ICT proficiency, and erratic power supply. Thus, this study recommended that management teams of universities in Nigeria commit adequate funding to procure ICT facilities, thus providing automatic standby generating plants and increasing incentives for library and digital preservation staff. Collaboration among stakeholders such as university libraries and the National Library of Nigeria should be encouraged to create a national union catalog of T/Ds in Nigerian universities and thus enable a platform for a national database. Access to IDRs will further strengthen worldwide university networking. This study will thus add value to the existing studies on ICT application in university libraries and e-resources in university libraries in Nigeria.
Efektivitas Pembelajaran Tatap Muka (PTM) di New Normal Terhadap Hasil Belajar Siswa Mata Pelajaran Pendidikan Kewarganegaraan
Authors: Waton Muhammad Nasrul
Published: February 2022

Education is a process of individual self-development of one's personality that is carried out consciously and responsibly to be able to improve knowledge, skills and attitudes as well as values ??so that they are able to adapt themselves with the environment. Many things change when re-learning is done with a face-to-face learning system (PTM) after three semesters of learning with an online system. A person will reap the results of his learning when he is interested in something he is learning. The research method used in this study is a quantitative approach to determine how much effectiveness learning in the new normal era has on the learning outcomes of class XI IPS 1 Madrasah Aliyah Darul Ma'arif Kedamean students on March 2021. To explain how the level of effectiveness of learning in the new normal era, the author uses the SPSS 16 for windows application as a tool to find out the results of the research. from the results of the study obtained data that explains how the effectiveness of learning in the new normal era is 73.5% with an interpretation that has a fairly high category. so that face-to-face learning in the new normal era can be said effectively implemented at Madrasah Aliyah Darul Ma'arif Miru Kedamean Gresik
Efektifitas Rancangan Undang-Undang Hukum Materiil Peradilan Agama (RUU HMPA) Dalam Penanggulangan Nikah Sirri
Authors: Rizal Faisol
Published: February 2022

The draft of Law on the Religious Courts Material Law is a draft law that is still in the stage of discourse and declaration by the authorities. This draft law has one article that is quite interesting to study, namely the law of punishment for sirri marriage.

As an eastern country that still follows eastern wisdom; and Indonesian people who are Muslim, there are still many practitioners who practice sirri marriage among the people. This is due to many factors including lack of marriage registration material, less socialized marriage regulations and others.

Many approaches are carried out by researchers from socialist circles, academics and historians who produce different assumptions about the problem of "reluctance to marriage records". This law is in accordance with the spirit of Islam in order to benefit. The maqashid syariah approach is an effective approach in combining positive law and shari'ah law.
MENGUAK PSIKOLOGI ISLAM MELALUI PENDEKATAN SEJARAH
Authors: Sudirman Sudirman
Published: February 2022

The psychological approach in Islamic studies has a significant role in explaining the external symptoms of religious people. Armed with psychological theories, it will be easy to know the level of religion a person understands, lives and practices. This paper aims to explain and analyze Islamic psychology based on a historical approach and analyze western psychology schools using an Islamic psychological approach. This study refers to the history of Islamic psychology from the 19th century to the modern era at this time, and also how the development of religious psychology. The results in this article are that humans have the potential to do good from the aspects of will, freedom, feelings, and thoughts to reveal the meaning of life based on monotheistic values ??so that humans are able to develop the potential and quality of Islamic life, namely by integrating the pyramid relationship between lust, intellect, and heart into the human psychological context based on the teachings of revelation that will give birth to a creative life as ordered by God in the Koran.
Analisis Hukum Islam Terhadap Kearifan Lokal Penetapan Jadwal Adzan
Authors: Rohman Moh. Faizur , Solikin Agus
Published: February 2022

Abstract: Adhan, which is a sign of the entry of prayer time, is usually held at the beginning of time. Different things happened in Datar, Putukrejo, Loceret, Nganjuk, East Java where the call to prayer was not done at the beginning of time, but according to the schedule set by the local kiai or village kiai. In line with that, this article is the result of studies that have been carried out at that location using qualitative research methods and data collection techniques, namely through interviews and observations. Meanwhile, the data analysis used is descriptive inductive analysis method with conclusion drawing approach. Based on the explanation of the research that has been carried out, it is concluded that the village Kiai in determining the adhan's schedule by integrating the fiqh prayer time with local wisdom in order to obtain harmony. The purpose of determining the schedule for the call to prayer is to form the character of the importance of congregational prayers in the life of the congregation they lead.
Pengaruh Lingkungan Bahasa terhadap kemampuan Berbicara Bahasa Arab
Authors: Unsi Baiq Tuhfatul
Published: February 2022

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RELEVANSI PENDIDIKAN PESANTREN DENGAN PENDIDIKAN MODERN
Authors: Ma’sum Muhammad Asrori
Published: February 2022

This article aims to elaborate the thoughts of KH. Hasyim Asy'ari about Islamic boarding school education as well as revealing aspects of modernity that are relevant to current educational conditions. The significance value of this research lies in the greatness of KH. Hasyim Asy'ari in changing the pesantren education system, starting from the intake of character that is moralistic in principle to the plains of institutionalization and curriculum. A major breakthrough that is impressive and remains relevant to the existence of education today. By referring to some of his literature and works, this paper combines theory of thought with policy action in the field through the existence of Pesantren Tebuireng, Jombang. The method used is a literature study (literature approach) with the type of qualitative research. The data is taken from articles, books and other documents. The data were analyzed using philological content analysis, in which the reading of KH's educational thoughts. Hasyim Asy'ari is associated with his current development. From the results of the study resulted in conclusions, 1) the source of educational thinking goals according to KH. Hasyim Asy'ari is to humanize in his position as a creation that gives birth to awareness to carry out his rights and obligations to God the creator of man, this is the embryo of the birth of character education; 2) Islamic education is not only religious knowledge in material terms, but also general knowledge. So the opening of the curriculum by accepting general material (non-religious) is needed by pesantren; 3) Islamic boarding schools must be responsive to the times, follow the flow of change without letting go of the dignity of the pesantren.
HUBUNGAN KEPERDATAAN ANAK DI LUAR NIKAH PERSPEKTIF SEJARAH SOSIAL HUKUM ISLAM
Authors: Nurcholis Moch. , Iqbal Muhammad
Published: February 2022

In Indonesia, children out of wedlock are only related to their mothers. This can be seen in Article 46 UUP. No.1 of 1974 and Article 99 of the KHI. The rules are presumably still based on the classical fiqh understanding of the termination of the lineage of children out of wedlock. Then the Constitutional Court made a decision that the child also has a civil relationship with his biological father. From this problem, two questions arise. First, how is lineage in Islamic law?. Second, how is the civil relationship between children out of wedlock from the perspective of the Social History of Islamic Law? When viewed from the focus of the study, this article includes historical-analytical research. When viewed from the operational data collection studied, this research is a library research. Primary and secondary data were analyzed using descriptive analysis method, by processing the study of the social history of Islamic law to find the meaning of civil relations. The approach used is a historical approach, which describes social phenomena in the past then drawn to the present to become more relevant. There are two research results: first, Based on the analysis, nasab which has been sacred, by some people it turns out that along with the development of the nasab era turned out to still be a difference among scholars with social development. Second, in the perspective of the Social History of Islamic Law, the Constitutional Court's decision regarding the civil relationship of children out of wedlock means the rights that exist within the lineage itself.
EFEKTIVITAS PEMBELAJARAN DARING PADA MASA PANDEMI COVID-19 DI SMK NURUL JADID PAITON PROBOLINGGO
Authors: Rudi Rudi , Septantiningtyas Niken
Published: February 2022

This research was conducted to identify the implementation of online-based learning in making learning effective during the pandemic at SMK Nurul Jadid Paiton Probolinggo. This study uses a qualitative approach by collecting some data in the form of information obtained from interviews with several predetermined informants, namely the principal, vice principal, teachers, and students at SMK Nurul Jadid Paiton Probolinggo. With the hope that this research intends to describe the effectiveness of this online learning in the pandemic period which is less than two years has stopped all sectors of life. Therefore this research was conducted. And also like the implementation of online learning at SMK Nurul Jadid Paiton Probolinggo.
A Bibliometric Analysis of Research on Business Incubator
Authors:   SMA Negeri 1 Karanganyar, Kabupaten Kebumen, Jawa Tengah, 54364, Indonesia, Putra Alif Jian Permana , Imron Mochamad Ali ,   Faculty of Science and Information Technology, Department of Management & Humanities, Universiti Teknologi PETRONAS, 32610, Perak Darul Ridzuan, Malaysia
Published: February 2022

This research aims to describe the development of research of incubator business management were published in the international scientific journal in scopus indexed. This research method is used descriptive quantitative to approach the analysis of bibliometric. Sources of data obtained from the database Scopus with restrictions articles were published ten years past. Data were analyzed using the analyze menu on Scopus and the VOSviewer software. The findings of this study are research publication of incubator business management are indexed in Scopus, period 2010 - 2020 as many as 530 articles by 986 authors and 190 keywords. The development of research in incubator businesses were published in the scientific journal Scopus indexed, period 2009-2020 are positive growth. The visualization bibliometric network map based on keyword is divided to eight clusters and a network map based on the authors is divided to four clusters. Keywords: Business Incubator Management, Bibliometric, Scopus, Vosviewer
Public Services Challenges during Covid-19 Pandemic in Indonesia
Authors:   Faculty of Administrative Sciences, Universitas Krisnadwipayana, Bekasi, 13077, Jawa Barat, Indonesia, Nazriah Ainun
Published: February 2022

The pandemic that is still hurting the world, including Indonesia, has pushed the government to innovate in all its policies and immediately make policies and improve public services for the benefit of the wider community. In addition, the COVID-19 pandemic and the demands of industry 4.0 which require the government to accelerate in making policies by utilizing technology in bringing progress to data and information systems, including improving services in the public sector. This period gave impetus to the government to boost innovation to improve various public services in various sectors, especially the health sector. This study uses quantitative methods with descriptive analysis methods. This study shows that the government has made many innovations in the management of resources and public sector services, but still encounters obstacles when collaborating with the private sector
Emotional Self Care
Authors:   Author Cum Freelance Content Writer, Sharma Dr. Shradha
Published: February 2022

Everybody needs self care at some point in their life. In this article, various emotional self care methods are suggested that can be executed in our lives. It benefits an individual in a way that he can manage his emotional health on his own and without the help of a counselor. This article improves our understanding of this beneficial concept and how we can inculcate emotionally healthy lifestyle habits by way of spending few hours a day on ourselves. We can nurture our emotional state, inner dialogues and honoring our feelings provided we start taking care for our emotional health and well-being Keywords: Self Care Healthy Lifestyle, Emotional Activities, Positive Thoughts, Handling Emotional Situations And Healthy Body
Impact of Covid on Religious Tourism in Rajasthan
Authors:   Associate Professor, Department of E.A.F.M., University of Rajasthan, Jaipur-India., K. Saxena Dr. Rajeev , Nair Manu ,   Research Scholar, Department of E.A.F.M., University of Rajasthan, Jaipur-India.
Published: February 2022

Social Tourist footfalls has plummeted in the first five months of the year because of the Covid epidemic. the number of tourists fell by more than 40% from January to May, compared to the same time previous year. The decrease was seen in both local and international tourist arrivals. Due to the shutdown, the number of domestic visitors was almost non-existent in April and May. In April, there were 86 international visitors and 115 in May. According to sources, these visitors were stranded in the state. This shortfall in the number of tourists have affected all the modes of tourism and related activities including religious tourism. All the temples and religious activities that has closed from the march 2020 is still in the closed condition. This closure has put a very inverse impact on the related and service providing institutions. Our study is based upon the religious tourism service providers views taken from 6 locations of the Rajasthan, very famous spots for the religious tourism including Brahma Temple, Pushkar, Galtaji Temple, Jaipur, Jain Temple, Ranakpur, Dargah Sharif, Ajmer, Dilwara Jain Temples, Mount Abu and Shrinathji temple, Nathdwara. A representative sample of 50 respondents from each religious site (total 300) were taken to measure COVID-19 impact on the Tourism for religious purposes at Rajasthan. Results revealed that the number of tourist camming for the country and forging have significantly dropped in year 2020 and nil for the two months April and May 2020. Further we have identified the problems and the way to remove the problems using the views of the respondents using the regression method to find out major problem and the way to improve the religious tourism in the selected sites of Rajasthan state. Keywords: Religious tourism, Rajasthan, tourists visit, Tourist service operators and COVID-19.
Ценностные основания гражданской активности: социологический анализ
Authors: Хрипкова Дианна Вазгеновна
Published: February 2022

Представлен анализ роли ценностных установок в реализации практик гражданской активности. Отмечено, что в последнее десятилетие уделяется особое внимание изучению влияния социокультурных факторов (ценностей, идей, традиций, религии и т.д.) на общественные процессы и взаимодействия. Под гражданской активностью в рамках исследования понимается деятельность индивидов, социальных групп, институтов гражданского общества по достижению общих для большинства целей, основанная на единстве ценностных установок, взаимном доверии, солидарности и ответственности. Сделан вывод о необходимости поиска источников солидаризации и консолидации в целях преодоления дефицита солидаристских ценностей в современном обществе.

Исследование выполнено за счет гранта Российского научного фонда № 21-18-00150
Absolute Scale Estimation Approach for Monocular Visual Odometry
Authors: Diaz Aldo , Kurka Paulo
Published: February 2022

Monocular visual odometry is an effective motion estimation technique that requires to solve for the challenging problem of absolute (metric) scale estimation. Current approaches use information such as the camera height or size of known objects to estimate the scene scale. In this paper, we propose a novel prediction-correction method to estimate the absolute scale of motion using camera height and flat ground assumption. Prediction is provided by a robust relative scale estimation strategy that exploits redundancy in depth information. Correction implements ground patch correlation using subpixel search refinement. The proposed method is tested using the public KITTI benchmark. As result, we derive analytical expressions to determine the absolute scale using a monocular camera. The empirical results shows the effectiveness of the proposed absolute scale estimation strategy in reducing the scale drift in monocular visual odometry.
Epidemiological and clinical significance of medico-social predictors and determinants in the development of relapses of pulmonary tuberculosis in adults and the management of medical asistance
Authors:   Institute of Phthisiopneumology ", Tudor Elena ,   Chiril Draganiuc",   , Republic of Moldova, Iavorschi Constantin ,   Institute of Phthisiopneumology "Chiril Draganiuc", Republic of Moldova, Brumaru Albina ,   Institute of Phthisiopneumology "Chiril Draganiuc", Republic of Moldova, Bolotnicova Valentina ,   Institute of Phthisiopneumology "Chiril Draganiuc", Republic of Moldova, Moscovciuc Ana ,   Institute of Phthisiopneumology "Chiril Draganiuc", Republic of Moldova, Corloteanu Andrei ,   Institute of Phthisiopneumology "Chiril Draganiuc", Republic of Moldova, Kulciţchi Stela ,   Institute of Phthisiopneumology "Chiril Draganiuc", Republic of Moldova
Published: February 2022

The article presents data indicating that at present one of the most important clinical problems is the relapse of pulmonary tuberculosis (TB) in persons from groups of medical and social risk. It is shown the frequency of the main medicosocial predictors and determinants that have the greatest influence on the epidemic situation for tuberculosis. And, it was also determined their role in the development, course and outcomes of relapses. It was found that the revealed features of pulmonary TB relapses in people with different social structures, including socially maladjusted categories of the population, indicate the need for differentiated measures for their timely detection and prevention. An action plan and a number of activities focused on the needs of people, ensuring the optimization of the provision of anti-tuberculosis care and social protection of this category of patients, are described.
Primary ciliary dyskinesia in children
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Selevestru Rodica , Eladi Veronica ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Leahu Alina ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Sciuca Svetlana ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova
Published: February 2022

Primary ciliary dyskinesia is characterized by impaired mucociliary clearance and contributes to the recurrence of recurrent and chronic upper and lower respiratory tract infections. In this paper we elucidated a clinical case confirmed in the Pneumology Clinic of the Institute of Mother and Child, where he was investigated by ECG, pulmonary Rg, pulmonary CT, saccharin test. Morbid history of persistent wet cough, mucopurulent sputum, nasal voice, difficult nasal breathing. Radiography of the paranasal sinuses showed signs of pansinusitis. At pulmonary CT, there were characteristic signs of chronic broncho-pulmonary processes - varicose and sac-shaped bronchiectasis, pleuro-pulmonary adhesions, fibro-atelectatic areas in various segments. Spirometry – moderate and severe restrictive and obstructive disorders.
Independent Dose Calculation when External Radiotherapy Cancer Patient Planning
Authors: Lebedenko I. M. , Kosenkova L. M. , Sannicova E. O. , Zaichenko O. S.
Published: February 2022

Purpose: Independent dose calculation (IDC) and quantitative processing of the calculating the 3D

CRT, IMRT, RapidArc results of patients irradiation plans was conducted. Criteria for passing the exposure plans for the implementation of radiation therapy was developed.

Materials and methods: An independent manual dose calculation of patient exposure plans was performed using 3D CRT, IMRT and RapidArc techniques. Discrepancies were obtained for three groups of

patients: 3D CRT group contained 1584 patients, the group of patients who received IMRT included

647 patients. The patient group, in which rotary mode RapidArc was performed, included 364 patients.

Results: As the analysis result of the IDC for 3D CRT, IMRT, RapidArc technologies, the quantitative indicators were ranked. The allowable discrepancies between the dose IDC and the dose calculated by the

TPS were proposed for consideration: for 3D CRT technology from –5 to +10 %, for IMRT from 1.5 to 6

times, for RapidArc from 1, 5 to 2.5 times. Outside the specified intervals, it is necessary to check and

reschedule plans or conduct verification.
Toxicological Impact of Cadmium and Copper Exposure in H. Exemplaris
Authors: Ojekunle Opeyemi Oluwadamilola , Olatoregun Damola , Good Sonya , Sodipe Ayodotun
Published: February 2022

Cadmium and Copper are both heavy metals of concern and toxic environmental contaminants. Due to copper’s excellent electrical conductivity, its most common use is in electrical equipment. Cadmium on the other hand, is not essential, although it is used majorly in batteries. Contamination with cadmium and copper metals stems mainly from anthropogenic activities but other natural sources also exist. Tardigrades are microscopic aquatic animals renowned for their tolerance towards extreme environmental conditions, this study is to investigate their tolerance towards heavy metals and how to ameliorate the potential hazardous effects with an antioxidant (Selenium). Antioxidants are substances that may protect the cells against the effects of free radicals, they are intimately involved in the prevention of cellular damage: the common pathway for cancer, aging, and some diseases. We hypothesized that Hypsibius exemplaris (H. exemplaris) has a low tolerance to a high concentration of toxicants and if Reactive Oxygen Species is released, some enzymatic pathways will be altered, but a certain concentration of Selenium will abate this effect, confirming the antioxidative capacity of Selenium. As was observed, cadmium and copper solutions increased Tardigrade sensitivity to oxidative stress as well as significantly reduced metabolism was observed. The produced reactive oxygen species was confirmed with fluorescence microscopy. Treating the exposed tardigrades with 0.5ppm of selenium using sodium selenite counteracted the cadmium and copper induced reactive oxygen species produced. The antioxidative enzymes produced were quantified using various assay methods. In conclusion, from an environmental perspective, selenium is a relevant antioxidant using the appropriate dosage.
Distance Teaching and Learning of Science during the COVID-19 Pandemic in Greece: Views of K-6 Students
Authors: Mandrikas Achilleas , Stavrou Ioanna , Kyriakou Kyriakos , Stefanidou Constantina , Skordoulis Constantine
Published: February 2022

In this paper the findings from research conducted with primary education students (K-6) are presented, explicitly focusing on students’ views concerning how Science was taught through distance learning due to the COVID-19 pandemic during the school year 2020-21. The sample of 378 students was not satisfied by the distance teaching and learning of Science except for the increased use of supporting audiovisual resources. Some of the results that occurred due to this transition were technical connection problems, a lack of communication between classmates and their teacher, a lack of concentration by students, their limited personal participation and the absence of face-to-face experimentation. Consequently, the limited understanding of scientific concepts shaped the students’ preference for learning Science in real classroom conditions.
Assessment of the immune responses of macrophages in selective breeding pangasius families (Pangasianodon hypophthalmus) resistant to enteric septicemia of catfish (ESC)
Authors:   Faculty of Biology, Ho Chi Minh City University of Education, Ho Chi Minh City, Vietnam, Tran Dung T. P. ,   Research Institute for Aquaculture No. 2, Ho Chi Minh City, Vietnam,   Faculty of Fisheries, Nong Lam University, Ho Chi Minh City, Vietnam, Nguyen Sang V. , Vo Phuong H. , Tran Phuc H. , Huynh Quan T. T. , Nguyen Thinh H.
Published: February 2022

This study aimed to evaluate the non-specific immune responses of macrophages in two selective breeding pangasius family groups: high disease-resistant (A) and low disease-resistant (B) to Enteric Septicemia of Catfish (ESC) caused by Edwardsiella ictaluri. Fish were sampled at five different time points after infection with the bacteria E. ictaluri including before the infection process, 24hpi, 48hpi, 264hpi and 312hpi. There were 372 samples including 192 samples of fish in group A and 180 samples in group B. All of them were used to analyze the amount of melano-macrophage centers in the tissues of liver, kidney and spleen; phagocytosis activity (PA) and phagocytosis index (PI) of the anterior kidney macrophages. Results showed that (1) the number of melano-macrophages of group A fish was higher than that of group B at survey points during the challenge and the difference was significant at 48hpi; (2) PA and PI of group A were higher than that of group B in the period from 48 to 264hpi, specifically, the PI of group A was higher than that of group B, which was statistically significant at 48hpi. The results of this study showed that the differences in non-specific immune responses through melano-macrophages can improve the survival rate and life span of the high disease-resistant family compared to the low disease-resistant family after the challenge with Edwardsiella ictaluri.
Trial on artificial breeding and laviculture of giant razor clams (Cultellus maximus Gmelin, 1791)
Authors:   Agricultural Seed Center of Bac Lieu, Bac Lieu, Vietnam, Nguyen Hong T. , Dinh Nhan T. ,   Faculty of Fisheries, Nong Lam University, Ho Chi Minh City, Vietnam
Published: February 2022

The study was carried out with the aim of determining the reproductive parameters and performing the rearing of giant razor clams (Cultellus maximus Gmelin, 1791) at larval stage and postlarval stage with different diets. The results showed that the spawning rate was 62.22 ± 3.85%, the fecundity was 7.98 ± 0.67 million eggs/female, the relative fecundity was 48,081 ± 5,826 eggs/g female, the fertilization rate was 42.67 ± 4.47%, and the hatching rate was 44.19 ± 4.02%. The rearing at larval stage with different diets of algae was investigated ((T1.1): Nanochloropsis oculata + Isochrysis galbana; (T1.2): N. oculata + Chaetoceros muelleri; and (T1.3): N. oculata + Isochrysis galbana + C. muelleri). The results showed that T1.3 gave the survival rate, length and width of larvae, reaching 5.3 ± 0.91%; 1525.60 ± 48.90 μm and 918.20 ± 28.00 μm, respectively. The parameters obtained from T1.3 was significantly higher (P < 0.05) than that of T1.1 and T1.2. The rearing at postlarval stage with different diets was also studied as follow: (T2.1): N. oculata + I. galbana + C. muelleri; (T2.2): using commercial feed (Lansy and Frippak); and (T2.3): combination of 50% of T2.1 + 50% of T2.2. The results showed that T2.1 gave the survival rate, growth in length and width of postlarvae, reaching 11.83 ± 3.89%; 5.72 ± 0.61 mm and 3.31 ± 0.14 mm respectively. Growth parameters of T2.1 were significantly higher (P < 0.05) compared to that of T2.2 and T2.3.
Isolation and selection of carotenoid-producing bacteria from marine environment and determination of carotenoid extraction condition
Authors:   Faculty of Biological Sciences, Nong Lam University, Ho Chi Minh City, Vietnam, Le Cuc T. H. , Le Hoa T. M. , Tran Trang T. , Van Vi T. T. , Nguyen Phong V. , Bien Thanh T. L.
Published: February 2022

The carotenoid is a natural pigment group, which is gradual of interest because of its essential biological activities and great production potentials such as using low-cost material and easy to apply on a large scale. For further development of natural carotenoid products, in this study, fourteen yellow, red, and orange pigment-producing marine bacterial strains were isolated from 25 seawater samples collected along coasts of Phu Quoc island (Kien Giang province), Vung Tau City (Ba Ria – Vung Tau province), Can Gio district (Ho Chi Minh city), and Thang Binh district (Quang Nam province). These isolates were identified belong to seven genera Micrococcus, Kocuria, Microbacterium, Brevibacterium, Bacillus, Rhodococcus and Exiguobacterium with 96.7% - 100% of 16S rRNA sequences identity. Based on carotenoid producing ability and UV-absorbance profile, three of the isolates including Micrococcus sp. 64A3a (yellow), Exiguobacterium sp. YT09 (orange) and Rhodococcus enclensis strain RSA3 (red) were selected for investigation of carotenoid extraction conditions. Methanol at concentration of 100% with ratio of 1 g bacterial cells/10 mL methanol is suitable conditions for extraction of red, orange and yellow pigments from the isolates.
O impacto da sorologia positiva na adesão à terapia antirretroviral em jovens que vivem com vírus da imunodeficiência humana
Authors: Melo Matheus Fonseca de , Leitão Consuelena Lopes , Lawani Jaila Dias Borges , Guadalberto Eligelson dos Santos , Monteiro Carla Larissa de Souza , Caldas Thainá Guedes
Published: February 2022

Introdução: Sem a terapia antirretroviral (TARV), as pessoas que vivem com vírus da imunodeficiência humana (PVHIV) ficam sujeitas a infecções oportunistas e podem ir a óbito. Com a evolução do tratamento, a infecção pelo vírus da imunodeficiência humana se tornou uma condição crônica tratável, porém dificuldades psicossociais comprometem a sua adesão. Segundo a Organização Mundial da Saúde, os farmacêuticos são fundamentais na epidemia contra a aids. Para adaptar suas ações profissionais à necessidade de cada paciente, esses profissionais devem compreender os fatores psicossociais relacionados ao vírus. O Amazonas registrou 706 novos casos de vírus da imunodeficiência humana em 2019 e possuía 16.122 pacientes em terapia antirretroviral. A Policlínica Dr. Antônio Reis possui 850 pacientes ativos cadastrados para terapia antirretroviral. Deste total, 192 possuem idades entre 15 e 24 anos, correspondendo a 22,58% do total de pacientes da unidade. A amostra final do estudo é composta por 40 pacientes, que correspondem a 20,83% dos pacientes de 15 a 24 anos da unidade, sendo 35 do sexo masculino e 5 do sexo feminino. Objetivo: Avaliar os fatores sociais que influenciam na adesão à terapia antirretroviral de jovens que vivem com vírus da imunodeficiência humana. Métodos: Estudo qualitativo desenvolvido no Sistema de Atendimento Especializado da Policlínica Dr. Antônio Reis com 40 pacientes soropositivos de 15 a 24 anos submetidos a um questionário estruturado para avaliar o impacto psicossocial na terapia antirretroviral. Resultados: 72,5% dos pacientes avaliados compreendem correlação do vírus com a imunidade, 30% não aceitam a sorologia. 90% se sentem deprimidos e ansiosos. 45% já pensaram em desistir do tratamento e 5% já chegaram a desistir. Conclusão: Destacam-se, como agravantes para a adesão, as dificuldades nas relações interpessoais, medo da exposição, problemas familiares, aceitação da sorologia, ansiedade, depressão, efeitos colaterais dos medicamentos, informações errôneas sobre o vírus e dificuldade em adequar o tratamento à rotina.
Reclassificação dos casos de sífilis congênita: um relato de experiência no município de Fortaleza
Authors: Vasconcelos Lea Dias Pimentel Gomes , Sena Maria Vilani de Matos , Araujo Maria Alix Leite , Rocha Ana Fatima Braga , Maia Ana Maria Peixoto Cabral , Lima Neto Antonio Silva , Melo Adriana Lopes Lima , Paiva Marcos Cavalcante , Lopes Kilma Wanderley , Azevedo Camila de Souza Lima
Published: February 2022

Introdução: A sífilis tem impacto na vida reprodutiva em virtude da possibilidade de transmissão vertical. O Ministério da Saúde publicou a nota informativa nº2/2017, que altera os critérios de definição de casos de sífilis, com o objetivo de qualificar os dados no sistema de informação e diminuir a subnotificação. A vigilância epidemiológica tem responsabilidade de qualificar as maternidades para notificar a partir das novas definições. Objetivo: Rever a classificação dos casos de sífilis congênita. Métodos: Trata-se de um relato de experiênciar sobre a revisão dos casos de sífilis congênita baseada na nota técnica nº2/2017. Utilizou o banco de dados do Sistema de Informação de Agravos de Notificação de 2018 de Fortaleza (CE) contendo os casos notificados de sífilis congênita. Foram avaliados os casos descartados, casos de sífilis congênita com tratamento adequado e inadequado da gestante, revendo se todos os critérios de definição forma cumpridos. Foi realizado em março/2020. Houve capacitação com os responsáveis das vigilância das maternidades e das regionais de saúde para divulgação da nota informativa. Após, foram feitas visitas nas maternidades para analisar os casos notificados. Para reclassificação do caso utilizaram-se dados no prontuário da atenção básica e hospitalar. Resultados: Em 2018 foram notificados 907 casos de sífilis congênita. Desses, foram avaliados 251 casos em que deveriam ser revistos os critérios de definição, sendo 89 casos classificados como descartados, 118 em que a mãe teve tratamento adequado e 47 com tratamento inadequado. Após reclassificação houve uma redução de 190 casos de sífilis congênita em 2018. Desses, 170 casos foram classificados como crianças expostas a sífilis, 13 como cicatriz sorológica, 6 de outros municípios e 1 caso de sífilis adquirida. Conclusão: A redefinição dos casos de sífilis congênita fortaleceu a utilização dos critérios de definição da doença pelas maternidades, a integração entre atenção básica e vigilância das maternidades por meio do acesso ao prontuário eletrônico da atenção básica e a necessidade de visitas às maternidades para monitoramento.
Perfil clínico-epidemiológico e sociodemográfico de pacientes com vírus da imunodeficiência humana/aids coinfectados com Toxoplasma gondii em fronteira brasileira
Authors: Moro Janielle Chrislaine , Moreira Neide Martins
Published: February 2022

Introdução: Disfunções decorrentes da infecção pelo vírus da imunodeficiência humana tornam o organismo vulnerável a doenças oportunistas, e, entre as que acometem o sistema nervoso central, a toxoplasmose é a mais frequente. Objetivo: Investigar o perfil clínico- -epidemiológico e sociodemográfico e os fatores de risco de pacientes com diagnóstico de vírus da imunodeficiência humana/aids coinfectados com T. gondii em Foz do Iguaçu (PR). Métodos: Estudo comparativo e de abordagem quantitativa realizado com 332 pacientes vírus da imunodeficiência humana positivos, acompanhados no Serviço de Assistência Especializada em Foz do Iguaçu. As informações foram obtidas por meio de prontuários e aplicação de um questionário contendo 27 questões objetivas. A associação entre o estado parasitado (variável dependente) e as variáveis independentes foi avaliada com o teste de qui-quadrado (X2) e de Pearson. Todas as variáveis que obtiveram p8.804,0,20 na análise de qui-quadrado foram incluídas na análise multivariada odds ratio, intervalo de confiança 95%, 945, <0,05. Resultados: Dos 332 pacientes analisados, 111 apresentaram sorologia para toxoplasmose, indicando alta taxa de infecção por T. gondii. Houve prevalência entre aqueles com faixa etária 8.805, 18 e 8.804, 60 anos e que estudaram até a quarta série do ensino fundamental e o ensino superior (incompleto/completo) (p<0,05). Permaneceram na análise multivariada os fatores de risco: pacientes com terceiro grau (incompleto/completo) e que consumiam água de poço tiveram mais chances de adquirir a infecção por T. gondii em 0,2 e 3,0 vezes mais, respectivamente. Entre pacientes com diagnóstico para neurotoxoplasmose, 63,6% estavam com níveis de T CD4<200 e carga viral com níveis detectáveis. Foram detectados neurotoxoplasmose (3,31%) e toxoplasmose ocular (3,61%), 54,1% (60/111) dos pacientes possuíam T CD4<200, dos quais 56,8% (46/60) apresentaram resultado positivo para IgG anti-T. gondii. Conclusão: Este trabalho permitiu uma caracterização do perfil de pacientes infectados com vírus da imunodeficiência humana/aids e coinfectados com toxoplasmose em um município de tríplice fronteira, tratando-se de um estudo pioneiro na região.
Mortalidade de pessoas com vírus da imunodeficiência humana co-infectadas com coronavírus (COVID-19) no Piauí
Authors: Sousa Karinna Alves Amorim de , Araújo Telma Maria Evangelista de , Silva Meire Maria de Sousa e , Silva Zenira Martins , Veloso Marylane Viana , Saraiva Keila Marília da Silva
Published: February 2022

Introdução: A COVID-19 é doença infecciosa por coronavírus, na qual maioria das pessoas apresenta acometimento respiratório leve a moderado, recuperam sem necessidade de internação. No entanto, pessoas com comorbidades, entre elas imunodeprimidos, apresentam risco maior de agravamento na evolução. Objetivo: Caracterizar mortalidade de pessoas com vírus da imunodeficiência humana infectadas com coronavírus (COVID-19) no Piauí. Métodos: Estudo descritivo, quantitativo, transversal. Realizado em maio de 2021, por meio do levantamento dos óbitos de pessoas com vírus da imunodeficiência humana coinfectadas com COVID-19, ocorridos no período de abril de 2019 a abril de 2020. Os registros foram provenientes do sistema de informações de mortalidade e do sistema de controle logístico de medicamentos. Foram realizadas estatísticas simples. Resultados: Verificaram-se 195 óbitos de pessoas com vírus da imunodeficiência humana. Desses, 28 (14%) tiveram relação com COVID-19, sendo 60% do sexo masculino, 46% entre 40 e 59 anos, 61% pardos, 53% solteiros, 32% possuíam ensino fundamental e 36% tinham escolaridade ignorada, 21% eram autônomos e 36% possuíam ocupação ignorada, 58% tiveram dados ignorados quanto assistência médica, 57% residiam na capital, 71% tiveram o óbito investigado, 75% foi a óbito em 2020, 86% estavam cadastrados no sistema de controle logístico de medicamentos e faziam tratamento para vírus da imunodeficiência humana, com dispensa de medicação em 2020. Conclusão: A mortalidade de pessoas com vírus da imunodeficiência humana infectadas pelo coronavírus não difere muito de óbitos por COVID-19 na população geral. Constitui-se desafio o enfrentamento da doença por não haver tratamento medicamentoso específico para cura. São importantes vacinação de todas as pessoas vivendo com vírus da imunodeficiência humana, seguimento das medidas de prevenção da COVID, isolamento social para controle da transmissibilidade, qualidade na assistência em todos os níveis de atenção para redução da evolução grave e ocorrência de óbitos. Ressaltam-se limitações pelo curto período do estudo e não completitude de algumas variáveis na ficha de notificação do óbito. Enfatiza-se a necessidade de mais pesquisas na temática.
Fatores definidores da qualidade de vida de pessoas vivendo com vírus da imunodeficiência humana em municípios de pequeno porte
Authors: Marques Sergio , Oliveira Junior Reynaldo de Jesus , Oliveira Denize Cristina de , Cecílio Hellen Pollyanna Mantelo , Spindola Thelma
Published: February 2022

Introdução: A simplificação do tratamento com as terapias antirretrovirais promoveu mudanças na vida das pessoas que vivem com vírus da imunodeficiência humana, com reflexos na qualidade de vida. Objetivo: Analisar os fatores definidores da qualidade de vida de pessoas vivendo com vírus da imunodeficiência humana em municípios de pequeno porte no estado do Rio de Janeiro. Métodos: Estudo descritivo, com abordagem qualitativa, apoiado na teoria do núcleo central das representações sociais. Participaram 80 pessoas vivendo com vírus da imunodeficiência humana residentes e assistidos nos municípios de pequeno porte da região Médio Paraíba/Rio de Janeiro. Os dados foram coletados por questionário sociodemográfico e pela técnica de evocação livre de palavras ao termo indutor qualidade de vida. Os dados sociodemográficos foram organizados no software Excel e apresentados em tabelas. As evocações foram analisadas pela técnica de análise de similitude por coocorrência. Essa técnica revela a quantidade de conexões que uma palavra mantém com as outras por meio do cálculo dos índices de similitude entre os conteúdos mais evocados, possibilitando a construção da árvore máxima, que sintetiza graficamente o conjunto das conexões existentes. Resultados: A população estudada, em sua maioria, é jovem, do sexo masculino, com baixa escolaridade, que vive com companheiros(as) e refere não possuir nenhuma sintomatologia relacionada à infecção pelo vírus e/ou ao uso da terapia antirretroviral. A análise de similitude retratou que os elementos que estabelecem maior quantidade de conexão são boa alimentação, atividade física e lazer. Avalia-se que o grupo estudado considera que a qualidade de vida se define a partir das dimensões ligadas à promoção da saúde, como as boas práticas alimentares, as atividades de lazer e atividades físicas, possibilitando melhor saúde física e mental. Conclusão: Pode-se inferir que as pessoas vivendo com vírus da imunodeficiência humana da região do Médio Paraíba percebem que mantendo corpo e mente em harmonia asseguram a boa qualidade de vida pela manutenção da saúde.
Efeitos da medicação antirretroviral no contexto das manifestações orais de vírus da imunodeficiência humana/aids
Authors: Silva Jairo Marcio Moreira da , Maia Fábel Franklin de Souza
Published: February 2022

Introdução: A infecção pelo vírus da imunodeficiência humana é uma pandemia caracterizada pela portabilidade de um fator que altera o sistema imune e facilita o aparecimento e instalação de infecções oportunistas e processos neoplásicos, quando o infectado passa a apresentar uma doença conhecida como síndrome da imunodeficiência adquirida (aids). As manifestações orais da infecção pelo vírus da imunodeficiência humana são parte importante da enfermidade e componentes indicativos de sua progressão. Objetivo: Este trabalho tem como objetivo, analisar os efeitos dos medicamentos antirretrovirais nas manifestações orais de vírus da imunodeficiência humana/aids. Métodos: Estudo descritivo, do tipo revisão de literatura. Para isso, foi realizado levantamento bibliográfico nas bases de dados PubMed e Scientific Electronic Library Online (SciELO), nos quais foram utilizados os descritores em inglês “Oral manifestations”, “HIV” e “Antiretroviral Therapy”, resultando na busca inicial em 253 estudos publicados. Após aplicação dos critérios de inclusão e exclusão e leitura crítica dos títulos e resumos, 12 artigos foram selecionados para compor o presente trabalho. Resultados: Observou-se, nos artigos selecionados, que pacientes que utilizam medicamentos antirretrovirais demonstram uma redução na manifestação de doenças oportunistas ligados à redução na taxa de linfócitos TCD4. Com a estabilização do sistema imunológico e diminuição da carga viral no organismo, resultado da adesão à terapia antirretroviral, enfermidades como candidíase, leucoplasia pilosa e sarcoma de Kaposi apresentaram redução na sua incidência nos trabalhos analisados. Os estudos indicam, ainda, um aumento nas manifestações bucais relacionadas ao uso de antirretrovirais, como papiloma, hiperpigmentação, xerostomia e desordens das glândulas salivares. Conclusão: Com isso, os estudos incluídos demonstram uma boa efetividade dos antirretrovirais na estabilização do sistema imunológico dos pacientes com vírus da imunodeficiência humana/aids com repercussões na manifestação de doenças oportunistas em cavidade oral.