bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of infrared thermography in the study of the osteopathic correction results in patients with amputation defects of the lower extremities
Authors: Kolyshnitsyn N. Yu. , Mokhov D. E. , Smirnova L. M. , Fogt E. V. , Ermolenko T. V.
Published: February 2023

Introduction. The main medical consequences of amputations are: phantom pain syndrome, degenerative changes in soft tissues, increased muscle tone of the stump, deterioration of microcirculation in the amputated limb. Methods of rehabilitation of such patients are physical therapy, physiotherapy, psychotherapy, mechanotherapy. The search for new methods of rehabilitation of patients with amputation of the lower limb is constantly underway due to the social significance of this disease. Osteopathic correction has proven effects of normalization of muscle tone, improvement of blood circulation, which can be assessed using infrared thermography.

Aims: to evaluate the effect of osteopathic correction on blood circulation in the stump in patients with transtibial amputation.

Materials and methods. The study includes 30 patients (21 men and 9 women) with transtibial amputation, undergoing diagnostic examination using infrared thermography on an outpatient basis in Albrecht Federal Scientific Centre of Rehabilitation of the Disabled. Patients were divided in two groups in random: main group (n=15), receiving osteopathic correction, and control group, receiving sham therapy. Both groups were divided in subgroups depending on amputation cause: cardiovascular diseases and trauma. Regardless the group infrared thermography was performed before and after first session of therapy or osteopathic correction and before and after second session. On thermograms, the temperature of the distal part of the stump was evaluated, the second limb — in the projection of the distal part of the stump.

Results. The method of infrared thermography objectively confirmed the positive effect of osteopathic correction on blood flow in the lower leg stump: in patients with traumatic and vascular genesis of amputation — in the form of a decrease in the severity of distal hypothermia after the first, before the second and after the second session of osteopathic correction compared to the data before osteopathic correction. In the control group, there was also a statistically significant increase in the temperature of the distal part of the stump after the first session and the second sessions of sham therapy, which returned to its original values before the second session, which indicates the short-term nature of the changes.

Conclusion. The study showed an improvement in blood circulation in the truncated limb, confirmed by an increase in the temperature of the stump in patients with transtibial amputation of traumatic and vascular genesis, which underwent osteopathic correction.
The use of autoimmunological parameters to evaluate the results of osteopathic correction: pilot study
Authors: Ikhlef A. , Potekhina Yu. P. , Tregubova E. S. , Kurbatov O. I. , Pukhalenko A. I.
Published: February 2023

Introduction. Osteopathic correction (OC) is aimed to eliminate somatic dysfunctions, which are reversible structural and functional disorders of tissue mobility. Adaptation mechanisms of the organism imply structural 

The aim of the study is to investigate the fundamental possibility of using functional (not nosological) autoimmunological indicators to evaluate the results of osteopathic correction.

Materials and methods. The prospective study was conducted on the basis of the Department of Osteopathy of the Mechnikov NWSMU and the Institute of Osteopathy (Saint-Petersburg) in 2020–2021. 10 young and middle-aged people (20–52 years old) were examined. Patients underwent osteopathic correction in the amount of 2–3 sessions. Patients were examined according to the algorithms of osteopathic diagnostics; the ratio of antibody titers to 24 autoantigens of various body tissues and organs was evaluated using the ELI-Viscero-Test-24 method before and after the OC courses.

Results. The relative content of autoantibodies to the main connective tissue protein collagen significantly (p=0,037) increased from a median value of 6 % (Q1–Q3 2–9 %) to 11 % (Q1–Q3 2–22 %). The other autoimmunological indicators varied in different directions.

Conclusion. It is likely that OC triggers the processes of connective tissue restructuring, which are reflected in an increase in the indicators of auto-AT to collagen. Changes in other autoimmunological indicators require more detailed studies on a larger sample.
How do microbes grow in nature? The role of population dynamics in microbial ecology and evolution
Authors: Fink Justus , Manhart Michael
Published: February 2023

The growth of microbial populations in nature is dynamic, as the cellular physiology and environment of these populations change. Understanding the growth dynamics of these populations has wide-ranging consequences for their ecology and evolution; it may also be critical for clinical and environmental applications in which we need to promote or inhibit microbial growth. Here we review the latest efforts to measure population dynamics of microbes in natural environments. We then address the role of population dynamics, especially tradeoffs in growth traits, in mediating ecological coexistence of multiple species. Finally, we discuss how population dynamics and evolutionary processes form a feedback loop that ultimately shapes the evolved patterns of growth we observe. We identify the major gaps in our current knowledge for each of these topics and what future work will be required to close them. We conclude with a brief outlook on the future of microbial population dynamics research.
CPW Fractal Antenna with Third Iteration of Pentagonal Sierpinski Gasket Island for 3.5 GHz WiMAX and 5.2 GHz WLAN Applications
Authors: Hafizun Ab Rashid Amier , Hisham Ahmad Badrul , Zoinol Abidin Abd Aziz Mohamad , Hassan Nornikman
Published: February 2023

Nowadays, the compact and multiband antennas are typically required for personal communication devices in the continuously developing wireless communication industry. The fractal antenna with the third iteration of the pentagonal Sierpinski gasket island for WiMAX and WLAN applications is presented in this work. It starts with the fundamental design of the square patch (Antenna A1) and pentagonal patch (Antenna A2). This simulation work is done using CST Microwave Studio simulation studio by applying the concept of the zero, first, second and third fractal iteration. Then, it goes on to use the fractal geometry concept of the Sierpinski gasket island structure with three designs step. The designs consist of the first iteration (Antenna B1), second iteration (Antenna B2) and third iteration (Antenna B3) of fractal geometry. The simulation work of Antenna B3 is compared with the fabrication work of the same design. After that, the measurement of the Antenna B3 is done in laboratory with - 29.55 dB at 3.41 GHz and - 20.40 dB at 5.28 GHz for its operating frequencies with bandwidth of 3.52 GHz and 5.48 GHz, respectively. At targeting 3.5 GHz WiMAX, 5.2 GHz WLAN application and 7.24 GHz of Antenna B3, the antenna shows the – 17.78 dB, - 29.63 dB and – 22.73 dB, respectively, and this value is feasible for WiMAX and WLAN operation.
A Performance Enhancement of Deepfake Video Detection through the use of a Hybrid CNN Deep Learning Model
Authors: Thaseen Ikram Sumaiya , V Priya , Chambial Shourya , Sood Dhruv , V Arulkumar
Published: February 2023

In the current era, many fake videos and images are created with the help of various software and new AI (Artificial Intelligence) technologies, which leave a few hints of manipulation. There are many unethical ways videos can be used to threaten, fight, or create panic among people. It is important to ensure that such methods are not used to create fake videos. An AI-based technique for the synthesis of human images is called Deep Fake. They are created by combining and superimposing existing videos onto the source videos. In this paper, a system is developed that uses a hybrid Convolutional Neural Network (CNN) consisting of InceptionResnet v2 and Xception to extract frame-level features. Experimental analysis is performed using the DFDC deep fake detection challenge on Kaggle. These deep learning-based methods are optimized to increase accuracy and decrease training time by using this dataset for training and testing. We achieved a precision of 0.985, a recall of 0.96, an f1-score of 0.98, and support of 0.968.
Gambarkan Asuhan Keperawatan Pasien Cedera Kepala Ringan (CKR) dengan Kebutuhan Rasa Nyaman Nyeri di Ruang Lukas RSMM Kabupaten Mimika
Authors: Tasik Jani Rante , Tandilanga Adolfina , Julianty Turena Indah , Pasang Meyke Tiku , Iksan Ricky Riyanto
Published: February 2023

ABSTRACT Head injury is a condition where the structure of the head experiences an impact from the outside and has the potential to cause disturbances in brain function. Purpose of the study Knowing Describes Nursing Care of Patients with Mild Head Injury (CKR) With Needs for Pain Comfort in the Luke Room RSMM, Mimika Regency Research method: The research design used in This case study is a descriptive research. This research is directed to describe or illustrate how the application of nursing care to mild head injury patients in fulfilling the needs of pain comfort at RSMM Regional Mimika Regency. Results From the results of the cases that have been described regarding nursing care in patients Mr. O with mild head injury (CKR) in fulfilling the need for pain comfort in the Lukas room RSMM District. Conclusion There is an effect. Keywords: Injury, Pain, Comfortable, Head  ABSTRAK Cedera kepala adalah kondisi dimana struktur kepala mengalami benturan dari luar dan berpotensi menimbulkan gangguan pada fungsi otak Tujuan penelitian  Mengetahui Menggambarkan Asuhan Keperawatan Pasien Cedera Kepala Ringan (CKR) Dengan Kebutuhan Rasa Nyaman Nyeri di Ruang Lukas RSMM Kabupaten Mimika Metode penelitian :   Desain penelitian yang digunakan pada studi kasus ini adalah penelitian deskriptif. Penelitian ini diarahkan untuk mendeskripsikan atau menggambarkan bagaimana penerapan asuhan keperawatan pada pasien cedera kepala ringan dalam pemenuhan kebutuhan rasa nyaman nyeri di RSMM Daerah Kabupaten Mimika. Hasil Dari hasil kasus yang telah menguraikan tentang  Asuhan keperawatan pada  pasien Tn. O dengan cedera kepala ringan (CKR) dalam pemenuhan   kebutuhan  rasa nyaman nyeri  di ruang  Lukas   RSMM Kabupaten Kesimpulan ada pengaruh Evaluasi yang dilakukan pada pasien dengan nyeri akut cidera kepala ringan menunjukkan penurunan skala nyeri 2 sesuai dengan kriteria hasil yang telah ditetapkan menurut teori. Kata Kunci: Cedera, Nyeri, Nyaman, Kepala
Prevalence of Hepatitis A Virus and Hepatitis E Virus in a tertiary care hospital, East Delhi, India.
Authors: Jain Charu , Birahman Nikita , Das Sukhla , Sinha Swati , Singh N.P
Published: February 2023

Background & Aim: Acute viral hepatitis (AVH) is a condition that is known to be caused by enterically transmitting Hepatitis A virus (HAV) and Hepatitis E virus (HEV). Usually, they result in self-limiting disease but can be seriously threatening if complications arise. This study was done to determine the prevalence rate of HAV and HEV in a tertiary care hospital in East Delhi, India.

Material & Methods: The retrospective and observational study of 2-year duration was conducted in the Department of Microbiology at UCMS and GTBH Delhi, India. A total of 410 samples from patients presenting with a clinical diagnosis of acute hepatitis were considered in the study. The serum samples were analysed for IgM anti-HAV and IgM anti-HEV, respectively, using commercially available ELISA kits.

Results: The seroprevalence of HAV and HEV were 2.19% and 0.24%, respectively. No case was found to be reactive for both parameters, indicating no case of co-infection. The majority of clinical samples were from female patients.

Conclusion: The incidence of HEV and HAV illnesses suggests that East Delhi has a lower prevalence rate of the reported viral illnesses. This finding suggests one of the following: limited circulation of the agents, good sanitary conditions, and/or protective immunity among the population tested. Nonetheless, we should continue to assess the ongoing conditions and take measures to improve them.
Особливості мотиваційної готовності в дітей у психологічній літературі
Authors: БУЖИНЕЦЬКА Ксенія
Published: February 2023

У статті розкрито питання психологічної готовності дітей до навчання в школі. Метою статті є роз-криття питання психологічної готовності дошкільників з порушеннями когнітивного розвитку донавчання в школі та методики дослідження їх навчальної мотивації. У дослідженні, для досягненняпоставленої мети і розкриття тематики, були використані методи пошуку, аналізу, систематизації йузагальнення дослідженого матеріалу.Досліджено психологію мотивації XІХ та ХХ ст. Доведено, що в середині XІX ст. предмет, межі іспецифіка психології мотивації досліджувалися в контексті поведінкової психології, а вже в XX ст.сфера дослідження мотивації набуває ширших меж і фактично розподіляється між соціально-ког-нітивною психологією.Визначено провідну роль мотиваційної готовності, яка є визначальною в успішному навчанні й адапта-ції дитини до школи. Проаналізовано психолого-педагогічні дослідження з означеної проблематики.Ви-окремлено мотиви (зовнішні – отримання хорошої оцінки, підвищення свого престижу, уникнення непри-ємностей тощо і внутрішні – навчально-пізнавальні), які обумовлюють навчальну діяльність дошкільників.За допомогою експериментального тесту О. Венгера «Мотиваційна готовність» визначено орієн-тацію дошкільника на позитивне ставлення до школи, інтерес до процесу і змісту навчання дітейз порушеннями когнітивного розвитку. Виявлено, що готовність дитини до навчальної діяльностіхарактеризується її слабкою орієнтацією на позитивне ставлення до школи, низьким інтересом дозмісту і процесу навчання. Окреслено завдання, які спрямовані на подальше вивчення мотиваційноїготовності до навчання дошкільників з когнітивними порушеннями.Таким чином, проведене дослідження свідчить, що мотивація до навчання в дітей з когнітивнимипорушеннями не сформована. Готовність до навчальної діяльності характеризується слабкою орі-єнтацією дитини на позитивне ставлення до школи, низьким інтересом до змісту і процесу навчан-ня. Через порушення розвитку когнітивних процесів у дошкільників виникають труднощі в процесіпізнавальної і навчальної діяльності.
СТРУКТУРА ПОРУШЕННЯ ПРИ ДИСГРАФІЇ В ОБРАННІ КОРЕКЦІЙНОГО МАРШРУТУ
Authors: Якимчук Ганна
Published: February 2023

У статті розглядається проблема урахування структури порушення в розробленні напрямків корекційно-розвиткової роботи з подолання дисграфії у дітей молодшого шкільного віку, що є актуальним у зв'язку із активною інтеграційною політикою в сфері освіти. Вивчено сучасні вітчизняні та зарубіжні дослідження у сфері логопедичної теорії та практики згідно обраної теми. Організовано цілеспрямоване обстеження дітей із дисграфічними проявами в умовах логопедичного пункту. За результатами дослідження описано категорії дітей у межах даного порушення мовлення. Доведено необхідність поглибленого вивчення індивідуальних компонентів структури порушень при дисграфії в залежності від причини, складності, поєднання з іншими порушеннями розвитку. Представлено методику вивчення дітей з порушеннями писемного мовлення.
Сomponent strategies of foreign economic development
Authors: Imnadze I.N.
Published: February 2023

The main components of the foreign economic development strategy are considered in the article.

The success of the enterprise's foreign economic activity depends on a large number of internal reserves and external factors, among which the choice of the enterprise's foreign economic development strategy plays a significant role.

The foreign economic development strategy of the enterprise is one of the components of the general strategy of the enterprise and is an action plan of the enterprise, which is directly related to entering the foreign market and winning the desired market share, expanding and maintaining the desired competitive position on it. And it is also a set of management decisions regarding the narrowing of the entire set of possible foreign economic actions of the enterprise to the set of the most effective from the point of view of the long-term goals formulated in the general strategy of the enterprise.

Strategic development of the enterprise is a mandatory provision in the formation of increasing the competitiveness of the enterprise on the market and optimization of its activities.

Understanding strategy as a plan of actions allows enterprises to decide on the main types of actions to enter foreign economic markets and to consolidate their position on these markets. On the other hand, the understanding of strategy as a general direction of development in foreign economic activity requires coordination of this type of strategy with the general choice of all existing directions, therefore it is important to determine its economic essence.

Thus, it is possible to draw conclusions regarding the disclosure of the essence of the concept of "foreign economic development strategy" - a clearly defined sequence of actions in the process, which is based on a functional approach in interaction with systemic, situational and process approaches to the management of the enterprise's foreign economic activities, aimed at the development and implementation of the foreign economic strategy activities as part of the general strategy of the enterprise based on its respective capabilities and taking into account the changes occurring in the external and internal environment for effective functioning, increasing the level of competitiveness and development in general.
Вплив штучного інтелекту на міжнародний digital маркетинг
Authors: Корсунова К.Ю.
Published: February 2023

Штучний інтелект надзвичайно сильно впливає на digital маркетинг. Бізнес-організації вирішують працювати над пошуком нових, ефективних методів digital маркетингу, окрім традиційних, щоб створити міцний імідж свого бренду та охопити цільових клієнтів якнайшвидше, а також для того, щоб впоратися з величезною конкуренцією у відповідних галузях.

Сьогодні штучний інтелект швидко стає невід’ємною частиною споживчого та корпоративного бізнесу. Безумовно, він може покращити методи ведення бізнесу та збільшити продажі за допомогою уважної та проникливої аналітики даних.

З радикальним збільшенням використання мережі Інтернет більшість клієнтів покладаються на пошукові системи, щоб знайти бажаний продукт або послугу.

Комунікаційна підтримка бренду підприємства забезпечує необхідну конкурентоспрожність та може стати ключовим фактором формування лояльного ставлення споживача, а також формування самого іміджу підприємства. При цьому може буде сформувано комплекс забезпечення комунікаційної підтримки бренду на основі інструментарію міжнародного маркетингу.

Це змусило провідні пошукові системи, наприклад Google, обрати поглиблене машинне навчання, яке дозволяє пошуковим системам знати людський сценарій і надавати їм відповідні дані. Аналізуючи особисті вподобання покупця за допомогою штучного інтелекту, маркетологи готові прогнозувати потреби покупця в майбутньому та охоплювати цільову аудиторію набагато кращим способом.

 Так виникає цілий клас нових явищ і процесів, які вимагають нового наукового осмислення і систематизації, концептуального теоретико-методологічного дослідження і обґрунтування їх сутності, а також розробки нового категоріального апарату і введення в науковий обіг системи нових взаємопов'язаних понять.

Інтернет-технології також змінюють способи взаємодії компаній зі своїми співробітниками, партнерами, конкурентами та постачальниками, а digital маркетинг розвивається з неймовірною швидкістю. Встигають за новими трендами тільки ті, хто швидко вміють змінюватися та адаптуватися до нових умов ведення бізнесу, продумуючи та проводячи високоякісну маркетингову стратегію.

ШІ слід розглядати не як загрозу для робочої сили, а радше як цінний інструмент, який може допомогти покращити якість роботи та підвищити продуктивність. ШІ можна використовувати для швидкого й точного аналізу великих обсягів даних, що дозволяє приймати більш обґрунтовані рішення. Крім того, штучний інтелект можна використовувати для створення ефективніших маркетингових стратегій, а також для більш швидкого та ефективного виявлення та вирішення проблем. Використовуючи штучний інтелект, підприємства можуть підвищити свою ефективність і продуктивність, а також забезпечувати співробітників більш змістовною та корисною роботою.
Концептуальний підхід до трансформації глобальної економіки з урахуванням розвитку глобальних ринків
Authors: Шевченко І.O.
Published: February 2023

В дослідженні розкрито концептуальні основи розвитку глобальної економіки за рахунок розкриття елементів глобальної економіки та простеженя їх взаємозвязку з розвитком глобальних ринків. В дослідженні автором зроблено висновок, що на сьогодні не існує чітко зазначеної мети глобальної економіки, тому наукова новизна дослідження полягає у здійсненні спроби надати власне визначення шляхом розкриття синонімічних категорій. Підгрунттям формування мети глобальної економіки в дослідженні виступили мета глобалізації, мета економічної глобалізації та концепція глобальної економіки. У структурі глобальної економіки повинні бути перерозподільчі механізми, за допомогою яких нації-держави могли б регулювати економічний розвиток і розподіляти вироблені матеріальні цінності в суспільних інтересах. Наукова новизна визначення мети глобальної економіки полягає у розкритті змістовних характеристик глобальної економіки та врахуванні фактору трансформаційного виклику та сталого розвитку. В роботі зазначено, що суперечливість та обмеженість в окресленні завдань спричинили необхідність надання авторського трактування завдань глобальної економіки, як один із пунктів наукової новизни.

Дослідження міжнародних документів та робіт вчених дозволило узагальнити принципи глобальної економіки та виокремити найбільш значущі. Методологія глобальної економіки базується на реалізації системного комплексного підходу до дослідження глобальних проблем не в статиці, а в динаміці світового розвитку, тобто в процесі глобальних трансформацій і глобалізації розвитку. Розвиток системи глобальної економіки в контексті сталого розвитку торкається багатьох аспектів економічного життя держав. Головним методологічним підходом дослідження є формування концептуальних положень глобальної економіки на основі теоретичних підходів та категоріального апарату. Методологічною основою дослідження виступають фундаментальні положення теорії глобалізації за допомогою яких в роботі досягнуто поставлену мету дослідження. Метою даного дослідження є розробка концептуального підходу до трансформації глобальної економіки з урахуванням розвитку глобальних ринків.
TEACHER'S OPINIONS ON USING WEB-BASED E-ASSESSMENT AND EVALUATION APPLICATIONS IN EDUCATION
Authors: Sarıgoz Okan
Published: February 2023

Whether assessment-evaluation, which is one of the most critical elements of the teaching process, is carried out according to the requirements and conditions of the age poses an important problem for both teachers and students. How digitalization is reflected in the assessment and evaluation part of teachers' lessons in today's schools is a question that needs to be answered in the light of this problem. This research aims to examine the opinions of teachers about web-based e-assessment and evaluation applications based on digitalization. The research was carried out with a phenomenological design within the framework of qualitative research approach. The study group consists of 44 teachers working in state high schools in Hatay, Turkey. The data were collected face to face through a semi-structured interview form consisting of 5 questions. Data analysis was performed with content analysis method, which includes coding, categorization, and theming processes. As a result of the analysis, 4 different themes (advantages, disadvantages, teacher efficacy, suitability of the program) were obtained. As a result of the research, it was concluded that digital e-assessment evaluation applications, which are web-based e-assessment evaluation tools, have advantages such as being time-independent and practical, and storing, as well as disadvantages such as technical problems, preliminary preparation and not being suitable for every course. In addition, results were obtained in the research, such as that the curricula are suitable for web-based e-assessments and evaluations and that various technological or hardware deficiencies in the school make digital e-assessments and evaluations difficult. It was revealed that eliminating the inadequacies of high school teachers in e-assessment and evaluation practices is also related to eliminating the deficiencies in the dimension of schools and students. Suggestions were made for practitioners and researchers to identify and remedy these deficiencies.
Keywords: e-assessment and evaluation, digital assessment, digital evaluation, web-based assessment-evaluation
THE EFFECTS OF SOCIOSCIENTIFIC ISSUES WITH THINKING WHEEL MAP APPROACH ON CURIOSITY TOWARDS STEM OF YEAR FIVE STUDENTS
Authors: Siew Nyet Moi , Ahmad Jamilah
Published: February 2023

This research was conducted to examine the effects of the socioscientific issue with the thinking wheel map (SI-TWM) approach on the curiosity towards STEM, the construct of Exploration and Acceptance. A teaching and learning (TL) module was developed to guide teachers in implementing the SI-TWM approach to enhance curiosity among year five students. Quasi-experimental quantitative research was conducted on 345 year five students (aged 11 years old) in urban primary schools in Tawau, Sabah, Malaysia. A total of three groups were assigned randomly, namely i) socioscientific issue with thinking wheel map approach (SI-TWM, n=115), ii) socioscientific issue approach (SI, n=115), and iii) conventional approach (CONV, n=115). The curiosity towards STEM questionnaire was developed to measure the level of curiosity towards STEM. Data analysis was performed using MANCOVA, ANCOVA, and effect size. The results of the MANCOVA analysis showed that there was a significant effect across the three TL approaches for curiosity towards STEM. Meanwhile, the ANCOVA analysis results showed a significant effect of the SI-TWM approach compared to the SI and CONV approaches on curiosity towards STEM, the construct of Exploration and Acceptance. The results of this research prove that the SI-TWM approach positively impacts the cultivation of students' curiosity towards STEM.
Keywords: curiosity towards STEM, socioscientific issue, thinking wheel map, year five students
LEARNING STYLES OF TALENTED PRE-SERVICE TEACHERS
Authors: Türker Üstün , Bostancı Özgür
Published: February 2023

The learning styles of students vary both among individuals and across different disciplines they choose to study. In higher education, academic discipline appears to be a key factor influencing students’ distinctive learning styles. This study, which aims to determine the dominant learning styles and models of talented pre-service teachers, was designed with the survey model. The study group research consisted of 1019 volunteer pre-service teachers who continued their education in Physical Education and Sports, Music, and Arts & Craft Teaching departments. In the study, the VARK Learning Style Inventory was used as a data collection tool; students were asked to answer questions in a digital environment through Google Forms. According to the research results, kinesthetic style is the dominant learning preference for pre-service teachers in the visual arts and sports sciences, and both kinesthetic and aural styles are the dominant learning preferences for pre-service teachers in music education. Although talented pre-service teachers tend to learn predominantly kinesthetic and aural styles when evaluated, 61.2% of pre-service teachers prefer to learn with a Multiple Learning Model, which covers the entire instructional diversity, rather than sticking to just one learning style.
Keywords: learning styles, learning preference, talented teacher, VARK
Prevalencia y factores de riesgo asociados a la obesidad infantil: revisión sistemática
Authors: Ojeda Caizaluisa María Belén , Peña Cordero Susana Janeth
Published: February 2023

Introducción. La obesidad infantil refleja interacciones complejas de factores genéticos, ambientales, sociales y conductuales, junto con los componentes nutricionales y los patrones de consumo de alimentos, convirtiéndose en un grave problema de salud durante las últimas décadas. Objetivo. Revisar en la evidencia científica sobre la prevalencia y factores de riesgo asociados a la obesidad infantil. Metodología. Se realizó una revisión sistemática de la literatura en las siguientes bases de datos: Pubmed, Scopus, Web Of Science, mediante la combinación de palabras clave lo que permitió seleccionar artículos en idioma español e inglés entre los años de publicación 2017 al 2021. Resultados. La prevalencia de la obesidad infantil al analizar los 17 artículos fue del 19,6%. Entre los factores de riesgo asociados se identificaron el tener antecedentes familiares de obesidad, hábitos heredados, el entorno social, malos hábitos alimenticios, pasar mucho tiempo frente a dispositivos electrónicos, el sedentarismo, la tensión y la disfunción familiar. Conclusión. Los antecedentes familiares, factores psicológicos, sociales y el estilo de vida juegan un papel importante en la obesidad infantil teniendo más probabilidades de desarrollar enfermedades no transmisibles. Área de estudio: Enfermería, gestión del cuidado al paciente.
Prevalencia y factores de riesgo de la diabetes mellitus en el embarazo: una revisión sistemática
Authors: Moreno Maza Jacqueline Andrea , Peña Cordero Susana Janeth
Published: February 2023

Introducción. La diabetes mellitus gestacional (DMG) es una forma transitoria de diabetes (intolerancia a la glucosa) que aparece o se reconoce por primera vez durante el embarazo. Objetivo. Determinar la prevalencia y factores de riesgo de la diabetes mellitus en el embarazo. Metodología. La revisión sistemática se realizó con datos bibliográficos, basada en el método PRISMA, para ello se consultó información en bases como Web of Science, Pubmed y Scopus, eligiendo publicaciones en idioma español e inglés de los últimos 5 años del 2017-2021. Resultados. La prevalencia de diabetes gestacional en los 17 estudios analizados fue de 16,6%, por lo tanto el desarrollo de DMG está directamente relacionado con factores como antecedentes de DMG, edad materna avanzada, aumento de la paridad, el índice de masa corporal (IMC) alto y antecedentes médicos junto con el nivel de educación de la mujer. Conclusión. La diabetes mellitus gestacional (DMG) es la alteración metabólica más común durante el embarazo, su prevalencia está aumentando, se correlaciona con diversos factores psicosociales, biológicos comunes y está asociada con malos resultados maternos, fetales y neonatales. Área de estudio: Enfermería, gestión del cuidado.
Graphitizing modification of the axial zone of cast iron rolling rolls in the liquidus-solidus temperature range
Authors: Khrychikov V. E , Meniailo H. V , Semenov O. D , Aftandiliants Y. G , Gnyloskurenko S. V
Published: February 2023

Purpose. To develop a method for calculating a process of graphitizing modification of unsolidificated liquid-solid zone to reduce transcrystallinity of the macrostructure and the amount of cementite in the center of castings. Methodology. The duration of solidification of the castings was determined by the kinetic curves of liquidus, solidus and pouring boundary in coordinates of relative thickness of the solidified metal layer – the parametric criterion of Gulyaev. Findings. A methodology for the process of modification of the axial zone of rolling was developed, the mass and time of adding aluminum were determined according to the amount of liquid-solid phase that remains after the solidification of the working layer. On the example of a rolling roll weighing 1115 kg, 0.488 kg of aluminum was added into liquid-solid zone after the working layer solidified. Movement of aluminum to the front of crystallization is provided by centrifugal forces and adding of aluminum along the height of the roll. Originality. For the first time, the kinetic curves of liquidus, solidus and pouring boundary have been plotted in coordinates of the relative thickness of the solidified metal layer x/R and /R2 – the parametric criterion of Gulyaev for rolled cast iron alloys cooled in chill-sand molds of various sizes. A methodology was developed for calculating the process of aluminum modification of the axial zone of rolling rolls after solidification of the working layer in the barrel which was set at the pouring boundary. The amount of aluminum depends on the remains of the liquid-solid phase. Practical value. Graphitizing modification reduces transcrystallinity of the macrostructure and the amount of cementite in the axial zone of castings. A promising direction for further development is the development of new methods for manufacturing castings due to physical and mechanical effects on the two-phase zone, deoxidation and alloying of the central zones of castings.
Data collection system with signal optimal-routine for the mining and environmental monitoring in Vietnam
Authors: Loan Pham Thanh , Thanh Le Xuan
Published: February 2023

Purpose. To develop a data acquisition which is optimized for suitable purposes in monitoring/warning or decision-making assistance in the field of geography accident in mining activities or agroforestry. Methodology. In activities related to mining, agroforestry and environmental monitoring, many climate factors must be taken into account including humidity, soil moisture or level of rainfall. Those data play a key role in pre-warning or assisting in decision-making for operators who are responsible for risk warning. In this paper, we present an optimized data acquisition system which is reasonable in cost, simple and easy in installation. The system includes a sensor station (SS) and a central station to collect data from specified monitoring points. The latter one is used to gather data from SS through a new and optimized Lora WAN communication system. When sending gathered data to a cloud sever, an assistant system based on 3G module is established to warn of abnormal scenarios of the mining procedure or environmental parameters. The system is experimented, tested and implemented in the North Mountain area (Northwest) of Vietnam. Findings. A development of an acquisition system with optimized-data for alarming/warning and monitoring in the field of geography accident, mining activities and environment. The system could get sensing signal in both direct way and indirect way despite of bad weather. Originality. An improved Dijkstra algorithm is implemented to optimize and simulate the routing paths of a network. The optimization could show the best way for getting signal from sensor station indirectly to other ones, then to the central station. Practical value. A simple, reasonable-cost and easy-installation system is formed for monitoring, risk warning in the field of geography, mining, and climate.
Peritoneal Lavage with Antiseptics in the Management of Peritonitis in Patients with Perforated Duodenal Ulcer
Authors: Islam Md Jafrul , Hossain AZM Shakhawat , Islam Md Majedul , Hossain Md Alamgir , Rahman Md Mizanur , Uddin Kamal , Uddin Md Nasir , Mahbub NAM Golam
Published: February 2023

Background : Postoperative wound infection is a common consequence following laparotomy for peritonitis. Peptic ulcer perforation followed by peritonitis remains as an important cause of mortality. In severe peritonitis, the use of exploratory laparotomy and intra-operative lavage with large amount of saline solution has been the standard of care to reduce risk of postoperative infections.
Objective: To compare the outcome between povidone iodine mixed normal saline (N/S) lavage and conventional normal saline lavage in the management of peritonitis in a tertiary care public hospital in Bangladesh.
Methodology: This was a randomized clinical trial conducted in the department of Surgery, Shaheed Ziaur Rahman Medical College Hospital, Bogura during July 2013 to December 2013. There were total 50 patients, selected by purposive sampling as a diagnosed case of peritonitis due to peptic ulcer perforation. All the patients were divided into 2 groups by using coin toss as group A (conventional N/S) and group B (povidone iodine mixed with N/S). The data were collected using the pretested data collection sheet. Results were tested by chi-square test to see their level of significance with a p-value at <0.05.
Results: The maximum (17, 34.0%) patients presented as peritonitis due to peptic ulcer perforation was from 18-30 years age group. The mean age of the patient was 29.16±9.25 years (age range: 18-61 years). The female to male ratio were 5.25:1 and 3.16:1 in group A and B respectively. Some (22, 44.0%) of the patients showed 13-18 hours delay since first symptom appeared. Fever (88.0% vs 80.0%), surgical site infection (SSI) (32.0% vs 24.0%), burst abdomen (20.0% vs 12.0%), intra-abdominal sepsis (8.0% vs 4.0%) were evident as postoperative complications in the groups A and B respectively. Only 1 (4.0%) patient died among group A patients due to sudden cardiac arrest. Mean hospital stay was a little lower among group B patients with milder complications and good outcome (though difference was not statistically significant).
Conclusion: The outcome was observed better in case of using povidone iodine mixed with normal saline for peritoneal lavage.
J Monno Med Coll June 2022;8(2): 36-39
Pathogenic Potential of Composted and Sundried Human Excreta from Eco-toilets in Bangladesh
Authors: Alam Md Ashraful , Ara Khorshed , Banu Sultana Shahana , Shamsuzzaman AKM , Ahmed Be Nazir , Mamun Abdullah Al , Rahman Mahmudur
Published: February 2023

Background: The concept of eco-toilets in Bangladesh was promoted by an NGO (Practical Action, Bangladesh). The ecotoilets are especially built to collect human excreta for using them as manure on the fields after appropriate treatment for 12 months.
Objectives: This study was designed to see the physical properties appropriate for fields and pathogenic potential to ensure the treated human excreta are safe for cultivator’s handling.
Methodology: The study was carried out in three phases during 2010 to 2014. A total of 210 composted faecal excreta were examined for physical properties like colour, odour, odour intensity, moisture, bacteriological examination for faecally transmitted potential bacteria and parasitological examination for ova / cysts of faecally - transmitted parasites to recommend whether these composted excreta were suitable for use as manure by the cultivators.
Results: Majority of the specimens in all three phases contained remarkable moisture: 22.3-80.0% in all specimens in phase I, a considerable number (16, 53.3%) contained 25% moisture in phase II and high moisture content (66.4%-78.9%) in 6(50.0%) of specimens in phase III. Bacteriological examination revealed no pathogenic organism in any specimen of the phases- although, some specimens in all phases showed growth of non-coliform bacteria. Parasitological examinations in all phases revealed ova/larvae of helminths of Ascaris lumbricoides (AL)/ Trichuris trichiura (TT)/ Strongyloides stercoralis (SS). No cyst or trophozoite of any pathogenic parasite, or oocyst of the cryptosporidium was found.
Conclusion: The composted excreta could not be adequately treated by sun-drying as indicated by high moisture content and were found not suitable to use as manure by cultivators in the field.
J Monno Med Coll June 2022;8(2): 44-47
Evaluation of the Clinical Features of Bronchiolitis in Paediatric Patients and Exploration of the Risk Factors
Authors: Hyder Rumy Tabrez , Ahmed Shafi , Ahmed ATM Faruque
Published: February 2023

Background: In general, bronchiolitis presents as a progressive viral respiratory illness in children younger than 2 years of age, most commonly between 2-6 months.
Objective: The study was conducted to assess the clinical presentations of acute bronchiolitis in infants and young children and to evaluate the individual characteristics and environmental factors which can increase the risk of severe disease and hospitalization.
Methodology: This descriptive study was conducted in the department of Paediatrics, Khwaja Yunus Ali Medical College and Hospital, Enayetpur, Sirajganj. A total of 70 patients were included in the study, who were admitted to the hospital with a clinical and radiological diagnosis of acute bronchiolitis and were followed up in the Paediatric department during January, 2021 to December, 2021. Data collection was done by using a questionnaire form and by physical examination. The information for the questionnaire was provided by the childrens’ mothers. The SPSS software was used for data analysis.
Results: According to the results of the study, 39(55.7%) children were infants, aged between 2-6 months, 21(30.0%) were between 7-12 months and 10(14.3%) children of more than 12 months of age. Boys (47, 67.1%) were affected more commonly than girls (23, 32.9%) in a ratio of 2:1. Some 60 (85.7%) of the children had siblings and 46 (65.7%) children lived in crowded environment at home. Many (25, 35.7%) parents of the children were cigarette smokers and 37(52.9%) children were given formula feeds. There was previous history of hospitalization among 14(20.0%) cases and 5(7.1%) children were pre-term. The most common clinical presentations of bronchiolitis were cough among 61(87.1%) cases, wheeze in 56(80.0%), respiratory distress in 49(70.0%) and feeding difficulty in 28(40.0%) children.
Conclusion: The risk factors for bronchiolitis were young age (2-6 months), presence of a sibling, a history of hospital admission, crowding and paternal smoking at home and formula feeding. The most common clinical presentations were cough, wheeze and respiratory distress.
J Monno Med Coll June 2022;8(2): 48-52
Development of a Technique for Chromatographic Analysis of Excipients in a Liposomal Dosage Form of a Photosensitizer Tetra-3-phenylthio-phthalocyanine Hydroxyaluminium
Authors: Antonova S. V. , Kolyachkina S. V. , Lantsova A. V. , Nikolaeva L. L. , Sanarova E. V.
Published: February 2023

Introduction. The Laboratory of Drug Formulation Development at the N. N. National Medical Research Center of Oncology developed a liposomal dosage form of FS tetra-3-phenylthio-pthalocyanine hydroxyluminide (TPHA) for which a simple, accurate and easily reproducible method of quantitative determination of the main active substance and excipients in the drug product was needed. High-performance thin-layer chromatography (HPTLC) was chosen as such a technique.

Aim. The aim of this work was to develop chromatographic methods for the quantitative determination of excipients in a liposomal dosage form of a tetra-3-phenylthiophthalocyanine hydroxyaluminium (TPHA).

Materials and methods. Determination of substances was carried out by the method of high-performance thin-layer chromatography (HPTLC) followed by TLC-densitometry. Substance TPHA 98 % (Federal State Unitary Enterprise "SSC "NIOPIK", Russia), placebo lyophilized liposomal form without TFHA in the composition (FSBI "National Medical Research Center of Oncology. N. N. Blokhin" of the Ministry of Health of Russia), egg phosphatidylcholine (96 %, CAS № 97281-44-2, EPC Lipoid, Germany), cholesterol (≥99 %, CAS № C8667, Sigma-Aldrich, Japan), sucrose analytical grade (CHIMMED, Russia) and various organic solvents.

Results and discussion. The selected mobile phase for HPTLC analysis: isopropanol: ammonia 25 % aqueous 80 : 20, separation time was 20– 25 min (l = 75mm), t = 20 °С. To visualize the spots of sucrose, phosphatidylcholine, and cholesterol, a 5 % solution of phosphomolybdic acid was chosen. The stability of the standard samples was confirmed on a series of prevalidation studies. Validation of the methodology was carried out.

Conclusion. For quantitative determination of sucrose, phosphatidylcholine and cholesterol in a new liposomal dosage form, the method of HPTLC with TLC-densitometry was chosen, which allows identifying all three components in the dosage form simultaneously. The method was validated.
Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Analysis of Riluzole in Human Plasma and Its Application on a Bioequivalence Study
Authors: Mohammadzadeh S. , Salmannejad F. , Mohammadzadeh M. , Ghari T. , Sadrai S. , Zaringhalam J.
Published: February 2023

Introduction. As the first approved drug for amyotrophic lateral sclerosis (ALS) treatment, riluzole is known as a glutamatergic neurotransmission inhibitor administrated in 50 mg tablets twice daily. For this reason, a generic product of riluzole has been developed at a lower price by Hogar-Daroo, Iran, which would benefit patients.

Aim. The objective of this study is to develop and validate a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the analysis of riluzole in human plasma samples and its application in the bioequivalence study of riluzole tablet.

Materials and methods. The chromatography was performed by using a C18 column (100 mm, 4.6 mm, 5 mm), 0.1 % formic acid and acetonitrile (60 : 40, v/v) as the mobile phase, at a flow rate of 0.90 ml/min in the gradient program. Carbamazepine was used as an internal standard (IS). The method employed only 100 µL of human plasma for quantification by a liquid-liquid extraction technique. The multiple reaction monitoring modes (MRM) was used for quantification of ion transitions m/z 235.0/165.9 and m/z 137.6/110.0 for riluzole and the m/z 236.9/194.0 for the IS. Dwell time was set at 200 ms.

Results and discussion. The calibration curve was linear over the concentration range 0.5–300 ng/mL. The lower limit of quantitation (LLOQ) was obtained at 0.5 ng/mL. The intra-day and inter-day accuracy ranged from 93.21 % to 101.34 % and 91.77 % to 104.88 % respectively. The intra-day and inter-day precision values ranged from 2.19 % to 5.69 % and 1.67 % to 5.31 % respectively, all within the FDA acceptable ±15 %.

Conclusion. The validated method was applied in Iranian healthy subjects under fasting condition with a 50 mg riluzole tablet successfully.