bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Acute Sprint Interval Training on Cognitive Performance of Healthy Younger Adults
Authors: Herold Fabian , Behrendt Tom , Meißner Caroline , Müller Notger G. , Schega Lutz
Published: April 2021

Considerable evidence has been accumulated showing that an acute bout of physical exercise can improve cognitive performance but the optimal exercise characteristics (e.g., exercise type and intensity) remain elusive. In this regard, there is a gap in the literature to which extent Sprint Interval Training (SIT) can enhance cognitive performance. Thus, this study aimed to investigate the effect of SIT on cognitive performance. We assessed in healthy younger adults (n = 19; 20.0 to 28.0 years old), the attentional performance (via d2 test), the working memory performance (via Digit Span Forward/ Backward) and the peripheral blood lactate concentration immediately before and 10 minutes after an exercise condition (SIT) and a control condition (i.e., reading). We observed that SIT can enhance specific aspects of attentional performance as it improved F% (t (19) = -2.249, p = 0.037, d = − 0.516) which constitutes a qualitative measure of precision and thoroughness. However, SIT did not change other measures of attentional or working memory performance. In addition, we observed that the exercise-induced increase in peripheral blood lactate levels correlated with changes in attentional performance (e.g., F% (rm = -0.54, p = 0.015)). The present study provides initial evidence that a time-efficient SIT can improve specific aspects of attentional performance and conforming evidence for a positive link between cognitive improvements and changes in peripheral blood lactate levels. Further research is warranted to substantiate our findings by investigating (i) the optimal exercise characteristics (e.g., number of sprints), (ii) further neurobiological mechanisms driving the cognitive improvements (e.g., changes in functional brain activation patterns), and (iii) the generalizability of the effects (e.g., older adults).
Adverse Childhood Experiences and Implications of Perceived Stress, Anxiety, and Cortisol Among Women in Pakistan
Authors: Ikram Naira , Frost Allison , LeMasters Katherine , Hagaman Ashley , Baranov Victoria , Gallis John , Sikander Siham , Scherer Elissa , Maselko Joanna
Published: April 2021

Background: Adverse Childhood Experiences (ACEs) are linked to poor maternal mental health. By disrupting stress regulation systems, ACEs are hypothesized to impact perceived stress, anxiety, and cortisol. This study explores the associations of ACEs with different manifestations of stress. Methods: Participants were part of the Bachpan study, a longitudinal birth cohort in rural Pakistan. Data were collected at the 36-month postpartum wave. ACEs were captured retrospectively using an adapted version of the ACE International Questionaire, and represented in the following ways: as a continuous variable, binary indicator, categoric levels, and subdomains (neglect, home violence, family psychological distress, community violence). Outcomes included: perceived stress (N=889) measured with the Cohen Perceived Stress Scale (PSS), anxiety (N=623) measured with the Generalized Anixety Disorder-7 scale (GAD-7), and hair-derived cortisol (N=90). Multivariable linear mixed models estimated associations between ACEs and the outcome variables. Results: All models featured positive associations between ACE items and PSS. Both the continuous total ACE score (B=0.4; 95% CI=0.0, 0.8) and the presence of any ACEs (B=1.0; 95% CI=-1.0, 0.3) were associated with higher anxiety symptoms on the GAD-7. Home violence (B=6.7; 95% CI=2.7, 10.8) and community violence (B=7.5; 95% CI=1.4,13.6) were associated with increased hair cortisol. Conclusions: All four ACE domains were associated with elevated levels of perceived stress, anxiety, and cortisol, with varying precision and strength of estimates, indicating that the type of ACE has a differential impact. This study disentangled adversity to understand the impact of specific adverse events on hypothalamic pituitary adrenal (HPA) axis functioning and mental health conditions.
Therapeutic Effects of Genetically Modified Wharton’s Jelly Mesenchymal Stem Cells Expressing Erythropoietin on Breast Cancer-related Anemia in Mice Model
Authors: Estiri Mohammad , Estiri Bahareh , Fallah Asghar , Aghazadeh Marzyeh , Sedaqati Amir , Abdollahi Abbas , Rabienia Mahsa , Mortazavidehkordi Nahid , Farjadfar Akbar , Ghorbani Mohammad
Published: April 2021

Cancer-related anemia (CRA) negatively influences cancer patients’ survival, disease progression, treatment efficacy, and quality of life (QOL). Current treatments such as iron therapy, red cell transfusion, and erythropoietin-stimulating agents (ESAs) may cause severe adverse effects including hemolytic transfusion reaction and the possibility of host immunity against rhEPO. Therefore, development of long-lasting and curative therapies is highly required. Combined cell and gene therapy platform can introduce a new route for permanent production of erythropoietin (EPO) in the body with various degrees of clinical benefits and avoiding the need for repeat treatments. In this study, we developed cell and gene therapy strategy for in-vivo delivery of EPO cDNA via genetic engineering human Wharton’s jelly mesenchymal stem cells (hWJMSCs) to long-term produce and secret human EPO protein after transplantation into the mice model of CRA. To evaluate CRA's treatment in cancer-free and cancerous conditions, at first, we designed recombinant breast cancer cell line 4T1 expressing herpes simplex virus type 1 thymidine kinase (HSV1-TK) by a lentiviral vector encoding HSV1-TK and injected into mice. After 3 weeks, all mice develop metastatic breast cancer associated with acute anemia. Then, we administrated ganciclovir (GCV) for 10 days in half of the mice to clear cancer cells. Meanwhile, we designed another lentiviral vector encoding EPO to transduce hWJMSCs. Following implantation of rhWJMSCs-EPO, the whole peripheral blood samples were collected from the tail vein once per week for 10 weeks which were immediately analyzed for the measurements of EPO, hemoglobin (Hb), and hematocrit (Hct) plasma levels. The blood analysis showed that plasma EPO, hemoglobin (Hb), and hematocrit (Hct) concentration significantly increased and remained at a therapeutic level for >10 weeks in both treatment groups which indicates that the rhWJMSCs-EPO could improve CRA in both cancer-free and cancerous mice model.
Classification of reproduction types of human capital in the context of state regulation
Authors: Benko Nadiia
Published: April 2021

The article examines the essence of the reproduction of human capital process, reveals its main stages (phases) –formation, distribution, exchange and consumption. The specificity of each stage of reproduction of human capital is considered, which makes it possible to realize the need for purposeful investment in a person and study the problems of state regulation at each of the stages.

The article also shows that the reproduction of human capital occurs at the individual, corporate and national levels.

Based on the study of the literature, a classification of the types of reproduction of human capital has been developed. This allows investing in human capital in order to create high quality human capital for the country. The classification of the types of reproduction of human capital is considered according to such characteristics as: the scale of reproduction, the nature of labor resources, the direction of reproduction, the innovativeness of the reproduction process, the completeness of the reproduction process, stages (phases, stages) of the reproduction process and structural components. The expanded reproduction of human capital is disclosed in detail, on which the state regulation of the economy of the most developed countries of the world is focused. The article notes the importance of the reproduction of human capital in providing an innovative "breakthrough" in engineering, technology, organization of production and management.

The influence of the process of reproduction of human capital on the development of the country's economy has been investigated. The necessity of enhancing the activities of the state to create conditions for the effective formation, distribution, exchange and use of human capital has been substantiated.

The role of the state in the formation (accumulation) of human capital through public goods for a person and through the establishment of norms and rules created in society and contributing to the development of this society is presented.
The influence of culture on the development of youth entrepreneurs in a selected suburb in Cape Town
Authors: Davids Nashwin , Tengeh Robertson , Duffett Rodney
Published: April 2021

Coloured people's entrepreneurial efforts in South Africa are mostly survivalist. Although most of the selected suburb's youth have high entrepreneurial intentions, most do not become successful entrepreneurs. We are hoping to understand why people think this. Indisputable are the inadequacy of entrepreneurial education and training, a heavily skewed distribution of resources, a lack of mentorship, minimal support from parents, and a cultural upbringing in opposition to entrepreneurship. This study's objective was to gain insight into the cultural and educational limitations on entrepreneurial development and the entrepreneurial intentions of the selected suburb's youth. This paper employed quantitative and qualitative research methodologies. The quantitative data was collected from 470 youths through a survey questionnaire. Ten personal interviews were conducted within the qualitative ambit and served to validate the quantitative tool's results. The quantitative data was analysed using SPSS software, and the qualitative data was analysed by identifying common themes in relation to the quantitative findings. The study revealed a low level of tertiary education, a family orientated culture and a high level of entrepreneurial intention. The findings further revealed that many parents do not run their businesses, which indicated that most of the youth do not stem from entrepreneurially oriented households. The researchers recommend that business incubators be established within the suburb and that schools within the community should partner with the private sector and governmental structures, such as the Department of Trade and Industry (DTI), The National Youth Development Agency (NYDA), and Small Enterprise Finance Agency (SEFA) in order to expose youth to the practical application of entrepreneurship.
Condition and problems of entrepreneurial subjects lending
Authors: Chernenko Olha , Vdovenko Iryna
Published: April 2021

Lending is a main instrument of bank institutions’ influence on the development of economy and its subjects. The aim of the paper is to analyze the condition of entrepreneurial subjects lending by the bank system, especially agrarian enterprises, and separation of main restraining factors of its development. During 2017-2020 there is observed an essential reduction of volumes of medium-term and long-term credits, given to entrepreneurial subjects. The use of short-term credits for less than 1 year, the most specific weight (80.5 %) of which is possessed by microentrepreneurial subjects with annual income less than 50 thousand euro, prevails. It has been established, that high cost of credit resources, absence of correspondent guarantee and insufficient competitiveness of most entrepreneurial subjects prevent the development of credit relations for all participants (borrowers, creditors and state). Agricultural economy that produces more than 12 % of GDP and provides more than 40 % of Ukrainian currency receipts, demonstrates positive financial results of activity, is really underfinanced at the expanse of bank credits. A share of credits, directed to the agrarian sector during last years, is essentially less than the contribution of the branch in the gross added value formation in the country. A bank credit policy, acceptable for all entrepreneurial subjects and directed on credit cost decrease and long-term lending increase, is necessary. Studies of the influence of arrangements in the AIC by reduction of credit prices on effective indices (pure profit of agrarian enterprises) has testified a close connection (R=0,9803), comparing with other factors, that is why the practice of using the preferential lending mechanism must be continued, but by stable, not continuously changing approaches and by direct state support of just small and medium entrepreneurial subjects, which are most limited in access to credit resources of bank institutions.
Study of structural and mechanical properties of sodium alginate gels
Authors: Gladukh Ievgenii , Podorozhna Maiia
Published: April 2021

Rheological parameters are an important characteristic of semisolid dosage forms. Structural and mechanical characteristics have a noticeable effect on the processes of release and absorption of drugs from ointments, as well as on their consumer properties: spreadability, adhesion, the ability to squeeze out of the tubes.

The aim: to study the rheological parameters of aqueous solutions of sodium alginate in various concentrations to create medicinal hydrogel compositions.

Materials and methods: sodium alginate (Shandong Topsea Seaweed Industrial Co., Ltd., China) was used as a gelling agent. The physicochemical properties of the samples were studied according to generally accepted methods of the State Pharmacopoeia of Ukraine. Rheological studies of experimental samples were carried out using a rotational viscometer «Rheolab QC», by Anton Paar (Austria) with coaxial cylinders C-CC27/SS at a temperature 20–25 °С.

Results and discussion: the rheological profiles of sodium alginate gels have a non-Newtonian type of flow, which makes it possible to characterize them as systems with plastic-viscous properties. Gels with a sodium alginate concentration of 1.5–2 % have the best indicators of yield stress, hysteresis loop area, mechanical stability and dynamic flow coefficients. This indicates a low degree of destruction of the structural grid in the process of mechanical action and the presence of thixotropic bonds.

Conclusions: sodium alginate gel base at 0.5 % and 1 % concentration is less stable under stress compared to sodium alginate bases at 1.5 % and 2 % concentration. The gel base of sodium alginate at a concentration of 2 % has the optimal mechanical stability value.
Aflatoxicosis of crucians: experimental treatment and biological value of fish
Authors: Petrov Roman , Pidlubniy Oleksiy
Published: April 2021

The aim of this study was to investigate a possibility to decrease a toxic influence of aflatoxin on the fish organism and veterinary-sanitary evaluation of fish, fed by a pure fodder, aflatoxin and ketoconazole+aflatoxin.

Fish aflatoxicoses cause essential losses at fish growing using industrial production technologies. It is characterized by decreasing weight gains and increasing kill of commodity fish, worsening fodder conversion. Farmers often use fodders of own production, without conducting laboratory studies, and don’t know about aflatoxins. At the same time because of different reasons, first of all economic ones, they don’t use adsorbents for decreasing the negative influence of aflatoxins on the fish organism. Their use doesn’t guarantee 100 % fish resistance to micotoxicoses and correspondingly product safety for a consumer. Fish, received aflatoxins with food, is dangerous as a food product for humans and animals. Aflatoxins are very stable in the environment, so even thermal processing doesn’t exceed risk of aflatoxin contamination.

The article presents a possibility of effective treatment of fish at aflatoxicosis. It is known, that aflatoxin beyond cells is not dangerous. Its activation takes place within a cell by the enzyme system cytochrome Р-450, forming an epoxide, in which result the aflatoxin inclusion complex with DNA forms in the kernel. The veterinary preparation “Ketoconazole” inhibits cytochrome enzymes Р-450, so aflatoxin activation within a cell doesn’t take place, epoxides don’t form, DNA cells are not injured, aflatoxicosis doesn’t develop in fish that has been proved experimentally. The veterinary-sanitary mark of fish, treated for aflatoxicosis, is satisfactory.  

The importance of this study is in fact that for today there is no developed effective method of fish aflatoxicosis treatment. An influence of aflatoxin on the crucian organism has not been studied experimentally
Discovering the values of generation X and millennial consumers in Indonesia
Authors: Helmi Arief , Sarasi Vita , Kaltum Umi , Suherman Yogi
Published: April 2021

Millennials and Generation X (Gen-X) are the fastest-growing market segment in Indonesia. The study aims to discover the salient values of those generations and to investigate their value differences. Data were obtained via questionnaires from 200 respondents of each generation. The questionnaires measure the importance of the values of each generation, consisting of nine values from the List of Values established by Kahle (1986), namely Sense of belonging, Excitement, Being well respected, Fun and enjoyment, Security, Self-fulfillment, Self-respect, Warm relationships with others, and Sense of accomplishment. This study employed factor analysis to identify sets of values representing their underlying values. This method resulted in three inherent values of Gen X and two of Millenials. Gen X shows the importance of Achievement, Family enjoyment, and Social relationship. Meanwhile, the Millennials are conspicuous by the values of Social recognition and Self-pleasing. Companies that choose Gen X as their target market can use their above-mentioned values to be expressed in their marketing strategies. Meanwhile, those who choose Millennials may use the two inherent values of this generation. This study fills a research gap on the characters of the emerging young generation segments in the country that can be adopted to generate market segment characters in the country.
Acknowledgment This work was funded by a research grant from the Universitas Padjadjaran, Indonesia.
Especies reactivas de oxígeno, estrés oxidativo y su relación con la destrucción tisular en periodontitis
Authors: Meñaca Guerrero Lorena , Suarez Causado Amileth , Díaz Caballero Antonio José
Published: April 2021

Durante la periodontitis se liberan mediadores inflamatorios y especies reactivas de oxígeno (ROS), cuando se incrementan producen estrés oxidativo. Este artículo de revisión describe el papel que desempeñan las ROS y el estrés oxidativo en el desarrollo y evolución de la inflamación y lesión tisular durante la periodontitis. Para ello, se realizó una revisión de la literatura en bases de datos como PubMed, ScienceDirect, Wiley Online Library, Springer, Plos one, Nature, Sage journals, Hindawi y Taylor & Francis Online, mostrando los siguientes resultados: las ROS producen daño directo e indirecto a los tejidos periodontales. Los daños directos incluyen peroxidación de lípidos, oxidación de proteínas y del ADN. Los daños indirectos involucran la regulación de las vías de señalización del factor de transcripción nuclear kappa B (NF-κB), la vía de la quinasa c-Jun N-terminal (JNK), las vías del inflamasoma y autofagia provocando la destrucción tisular y creación de un estado proinflamatorio en la periodontitis.
Uso de Biodentine para restaurar un molar permanente severamente afectado por la Hipomineralización de Molares e Incisivos
Authors: Gómez-Gómez Laura Marcela , Mejía-Roldán Juan Diego , Santos-Pinto Lourdes , Restrepo Manuel
Published: April 2021

La Hipomineralización de Molares e Incisivos (HMI) es un defecto cualitativo del desarrollo del esmalte que afecta de uno a cuatro primeros molares permanentes, pudiendo estar asociado con los incisivos permanentes. Se estima que la prevalencia mundial es del 14.2%, siendo América del Sur la región con mayor prevalencia (18%). Clínicamente, los dientes afectados por la HMI presentan esmalte poroso y blando, acúmulo de biopelícula, lesiones de caries dental e hipersensibilidad. Los cambios estructurales y químicos pueden afectar los procedimientos restauradores. El objetivo del caso fue reportar el uso de un material bioactivo para la restauración de un primer molar permanente severamente afectado por la HMI. Paciente femenino de 7 años de edad que presenta en el diente 36 una lesión de caries activa cavitada, hipomineralización severa con fractura posteruptiva y exposición de dentina e hipersensibilidad. Luego de realizar la remoción selectiva del tejido cariado, se puso un substituto bioactivo de dentina a base de silicato tricálcico (Biodentine). Un mes después, el diente se restauró definitivamente con resina compuesta. Al seguimiento clínico de 12 meses la restauración presenta adecuada adaptación marginal, forma anatómica adecuada y sin evidencia de lesión de caries dental secundaria. Radiográficamente se observa adecuada adaptación de la restauración y sin cambios en el espacio del ligamento periodontal y región periapical. El uso de materiales bioactivos muestra ser una alternativa promisoria para la restauración de molares severamente afectados por la HMI.
Rehabilitación de incisivos deciduos con pernos en fibra de vidrio y resina compuesta: reporte de caso
Authors: Zuluaga-Henao Carolina , Mejía-Roldán Juan Diego , Restrepo Manuel
Published: April 2021

La caries de la infancia temprana hace referencia a la presencia de una o más superficies cariadas, perdidas o restauradas en dientes deciduos en niños menores de 6 años de edad, siendo clasificada como severa cuando afecta a niños menores de 3 años. En dientes deciduos con gran destrucción coronal por caries dental, pero con integridad radicular, la rehabilitación puede ser compleja debido a la calidad y cantidad de estructura remanente. El objetivo de este caso, fue reportar la rehabilitación de cuatro incisivos deciduos severamente afectados por caries dental de la infancia temprana utilizando pernos en fibra de vidrio y restauraciones directas en resina compuesta. Paciente masculino de tres años de edad que presenta lesiones de caries dental activas y cavitadas y necrosis pulpar en los cuatro incisivos deciduos superiores. En la fase higiénica se realizaron actividades de educación, motivación en higiene y adecuación del medio bucal; en la fase restauradora se realizaron los tratamientos endodónticos, cementación de pernos en fibra de vidrio y restauraciones en resina compuesta con matrices anatómicas de celuloide y en la fase de mantenimiento se realizaron controles clínicos, radiográficos y actividades específicas de prevención. La rehabilitación con pernos de fibra de vidrio y resina compuesta logró reestablecer la forma, función y estética de los dientes del paciente.
Aesthetical perception of dental fluorosis in a Colombian low income community
Authors: Fragelli Camila , Restrepo Manuel , Girotto Bussaneli Diego , Jeremias Fabiano , De Cássia Loiola Cordeiro Rita , Escobar-Rojas Alfonso , Martinez-Mier E. Angeles , Dos Santos-Pinto Lourdes
Published: April 2021

Introduction and objective: The Dental Fluorosis (DF) is a development de­fect of enamel resulting from overexposure to fluoride and can aesthetically compromise the patient. This study aims to investigate the relationship be­tween aesthetic perception and dental fluorosis (DF) in a low-income com­munity with high DF prevalence. Materials and methods: A cross-sectional study was conducted with 171 Colombian schoolchildren aged 8 to 12 years living in low socioeconomic community (El Cedro, district of Ayapel, Córdo­ba, Colombia). After receiving authorization, the students were examined for DMFT and dmft indexes (WHO criteria), and for DF (TF index). The aesthetic per­ceptions were verified by the Child Perceptions Questionnaire About Tooth Appearance (CQATA). Data analysis was carried out using descriptive statis­tics, the chi-square test, the Student´s t-test, the one-way ANOVA test, and linear regression at a significance level of p ≤ 0.05. Results: The prevalence of DF in this sample was 84.8% (n=145). Only the presence of caries (DMFT/ deft≠ 0) had a significant impact on aesthetic perceptions. A significantly lower rate was found in girls for the report of pleasant color domain. The number of teeth affected by DF had a significant positive correlation with mean overall perception of dental health. Conclusion: The presence of mild DF in children with low socioeconomic status, from a population with a high prevalence of the condition, did not seem to have an impact on the report of pleasant color of teeth domain.
Fatores preditivos do sucesso endodôntico em tratamentos realizados por alunos de graduação§
Authors: Zajkowski Luciéli Andréia , Rodrigues Xavier Samantha , De Almeida Gomes Fabio , Kopper Móra Patrícia Maria Poli , Martos Josué , Feres Damian Melissa , Geraldo Pappen Fernanda
Published: April 2021

Introdução e objetivo: Ainda são escassos os estudos que avaliam com exatidão o sucesso do tratamento e retratamento endodônticos e quais as falhas que realmente impactam no desfecho dos mesmos. Determinar o índice e os fatores preditivos para o sucesso de tratamentos e retratamen­tos endodônticos, realizados por alunos de graduação com o mesmo nível de aprendizado. Materiais e métodos: Foram verificados os registros de proservação, com pelo menos 12 meses, dos tratamentos endodônticos realizados na Faculdade de Odontologia de Pelotas, analisando o sucesso ou o fracasso endodôntico, de acordo com critérios clínicos e radiográficos. As variáveis preditivas no resultado do sucesso do tratamento foram: dente, número de canais, coroa dentária, sintomas, diagnóstico da polpa e índice periapical radiográfico. As variáveis relacionadas ao tratamento foram: técnica de instrumentação, número de sessões e limite de instrumenta­ção apical. Resultados: 136 tratamentos endodônticos foram realizados com um acompanhamento de, pelo menos, 12 meses. A avaliação mostrou que o sucesso endodôntico foi influenciado pelo número de sessões (P = 0,015), diagnóstico inicial e grupo dentário (P= 0.014). Também foi possível observar que, quanto maior o índice periapical radiográfico inicial, pior o prognóstico endodôntico (P < 0.001). Conclusão: O índice de sucesso do tratamento endodôntico foi de 96.7% para casos de polpa vital, 87.5% para os casos de necrose pulpar e 92.9% em retratamentos. Estes índices fo­ram influenciados pelo dente tratado, diagnóstico inicial, índice periapical radiográfico inicial e pelo número de sessões utilizadas no tratamento.
Youth Attitude and Perception during the Covid-19 contingency in Morelia, Michoacan
Authors: Valenzo-Jiménez Marco Alberto , Lázaro-López Daniel Adan , Martínez-Arroyo Jaime Apolinar
Published: April 2021

Introduction: The worldwide contingency for Covid-19 disease has caused substantial changes in the lifestyle of the population, modifying consumption habits, and perceptions of individuals. In the case of young people, the pandemic has revealed problems, needs, and challenges related to health, violence, education, and employment.
Method: The objective of this study is to identify the perceptions of the young population aged 16 to 29 years in the city of Morelia, Michoacan, Mexico, during the health contingency of the Covid-19 disease generated by the new coronavirus SarsCov-2. The sample consists of 1386 cases, collected from May to July. The stratified sampling by quotas was used to ensure the representation of the entire young population in the metropolitan area of ​​the municipality. The measurement instrument consists of 48 questions divided into 5 elements: Perception of contingency, Physical and Mental Health, Education, Employment, and Consumption Habits.
Results: In the study, 847 women and 539 men participated, being 61.1% of feminine gender and 38.9% masculine individuals; 84.9% of the participating individuals declared to pass the contingency with family members. The marital status of the participants is 87.7% single, 6.3% married, and 7.9% in concubinage. 20.6% of the respondents declared to be in charge of children, and 18.3% to be in charge of people over 65 years old. 65.9% of the participants declared to stay at home and only leave for specific situations; On the other hand, government official press conferences and social networks, followed by open and pay-tv have been the most used media to be informed.  There is a strong interest in receiving information about Covid-19 and psychological care, as well as receiving consultations and medicines at home, also the main concerns of young people are the family and personal financial aspects. Areas affected by young people highlighted job stability, job opportunities, and are feared that school cycles will not be completed satisfactorily.
Discussion or Conclusion: The main findings of this study are that the young population of the city seeks official information from the Ministry of Health through electronic means, as well as consuming information such as government conferences. In the health section, the youths have declared substantial changes in their physical and mental health, related to confinement and physical distance measures. In the education section, the participants mentioned a decrease interest in academic issues and a considerable increase in the academic load. In the employment section, the youths declared changes in the way of working, using digital tools, reducing time in the workplace. Finally, an increase in frequency and quantity consumed of alcohol, tobacco, coffee, and other psychotropic substances is declared, in addition to the time of browsing on social networks and the Internet.
Guía interactiva de Zotero: aprovechar al máximo tu gestor bibliográfico
Authors: Tellier Florence Marie Véronique , Gimenez Lucas Hernán
Published: April 2021

Zotero es un gestor bibliográfico ampliamente usado en la redacción de textos académicos. Es un software gratuito, abierto y de libre acceso con distintas herramientas que facilitan la colecta, organización y uso de fuentes bibliográficas. En esta guía o manual, presentamos una manera de instalar y usar Zotero de forma sencilla, integrada y adaptable. El público objetivo de la obra es tanto el usuario principiante como aquello más avanzado. La guía está compuesta por dos archivos interactivos
COVID-19 and ARDS: Update on Preventive and Therapeutic
Venues
Authors: Narota Arun , Puri Gayatri , Singh Vikram P. , Kumar Ashwani , Naura Amarjit S.
Published: April 2021

:

A novel coronavirus SARS-CoV-2, which initially originated in China, has
outstretched to all nations and turned out to be an intense global concern for both the
governments and the public. In addition to the health concerns, the COVID-19 pandemic
has caused a tremendous impact on the economic and political conditions of every
nation. Ever since the start of the pandemic, the physicians were constrained to rely on
the management strategies due to a lack of clear understanding of the disease
pathogenesis caused by SARS-CoV-2 infection. Scientists are working tirelessly to
gather maximum information about the deadly virus and come up with various
strategies, which can be used against COVID-19 infection in terms of therapeutics and
vaccine development. It is quite evident that the virus infection leads to acute respiratory
distress syndrome (ARDS), and most of the deaths occur due to respiratory failure. As
the virus spreads through respiratory droplets, the strenuous exercise of preventive
measures and diagnosis at a large scale has been in practice across the globe to
prevent transmission. This review amalgamates the various updates and acts as an
umbrella to provide insights on SARS-CoV-2 mediated ARDS pathogenesis, the impact
of co-morbidities, diagnostics, current progress in vaccine development, and promising
therapeutics and immuno-modulatory strategies, highlighting various concerns and gaps
that need to be addressed to fight current and future pandemics effectively.
Immunogenicity of Nickel-Further Explored
Authors: Baghchechi Mohsen , Jacob Sharon E.
Published: April 2021

:

Recent reports of the relationship between nickel, allergy and autoimmunity have been described. However, there remains a paucity of information on the concordance between nickel sensitization and potency. Of note, an article by Drenovska et al. recommended a call for increased epidemiologic studies to define the prevalence of autoimmune syndromes induced by adjuvants such as nickel-containing metal implants. Accumulating reports of dermatologic manifestations following medical device implantation highlights the need for consideration regarding the potential sequelae following metal implantation. Considering the medical and the functional necessity of certain device materials, the authors agree calling for further epidemiological studies are needed to prevent metal-related autoimmunity, and additionally discover novel testing strategies.
The Beneficial Effect of Cannabis sativa Seed Oil on the Epidermis
Authors: Goscianska Joanna , Olejnik Anna , Galarda Aleksandra
Published: April 2021

Background:

Cannabis Sativa seed oil has become more and more popular in cosmetic industry
mainly due to the high content of antioxidants and unsaturated fatty acids that are desirable in
formulations because they prevent moisture loss and reduce the occurrence of dry skin.

Objective:

The aim of this study was to determine the effect of Cannabis Sativa seed oil on skin parameters
such as hydration and transepidermal water loss.

Methods:

The in vivo tests on volunteers with combination skin were performed by using corneometer
and tewameter.

Results:

The obtained results proved that Cannabis Sativa seed oil improved skin condition. The transepidermal
water loss decreased because the lipophilic components of the oil formulation tend to form
an occlusive layer on the epidermis surface. The highest increase in skin hydration was observed after
one week of treatment.

Conclusion:

These results confirmed that Cannabis Sativa seed oil has strong moisturizing properties
and can be recommended as a natural-based skin conditioning agent.
Intervenção social pelas/através das artes: Predisposições, desafios e propostas
Authors: Uribe Salomé
Published: April 2021

Starting from a bibliographic gap about people who intervene socially through and by the arts, without an academic canon, the sociology of culture and the sociology of the arts intersected in a work of sociological investigation. This crossing is the inspiration for the artists' singular biographies, to consider the social journey of the individuals as the explanatory/interpretative variable of their modes of social intervention by the arts. Throughout the construction of four life stories, we try to understand how ethos and practices simultaneously configure social interventions by the arts, namely through do-it-yourself (DIY) spaces, daily creativity, and identity resistance strategies. What are the common characteristics among these social intervention agents? What predispositions, challenges and proposals can we present? That is how we try to contribute to its conceptualization and recognition.
Comunidades colaborativas, arte e design no quarteirão Miguel Bombarda, Porto
Authors: Silva Ana Alves da
Published: April 2021

In this case study we intend to analyze the intersection of cultural and creative industries, independent projects and local micro businesses, collaborative communities, art and design generated at Miguel Bombarda Neighborhood in Porto. We take Pierre Bourdieu's habitus concept as reference, as it constitutes the human way of perceiving, judging and valuing the world according to a way of acting, as the result of individual biographical experience, collective history and interaction. We present the theoretical framework for a broader context on the social relevance of art and design which occupy the public space of the street. We developed a proposal for reflection as an active member of Miguel Bombarda Neighborhood community with and within its real-life context. Furthermore, we believe that it is possible to think the collective social space and design solutions capable of intervening directly in society.
Study of the possibility of using strapdown inertial gauges as part of the topographic location and navigation system of own design
Authors: Mikhaylov S. V.
Published: April 2021

Problem statement. During the operation of purchased navigation systems for topographic geodetic referencing and orientation, many shortcomings are revealed, mainly associated with software implementation, the correction of which is not always possible. A way out of this situation is creating own navigation complex from ready-made purchased meters and developed functional software (FSW). In this case, the primary task is to determine the preferable meters as part of the topographic location and navigation system (TLNS).Objective. Conduct a study of strapdown inertial navigation systems (SINS) of various manufacturers for compliance with the declared technical characteristics to determine a suitable meter for TLNS.Results. Information on the practical testing of studies the numerical estimates of standard deviations (SD) of errors in the determination and drift of grid azimuth, roll, and pitch of strapdown inertial meters in various climatic conditions, as well as under the influence of sinusoidal and broadband random vibrations (BRV) is presented. The values deviations of motion parameters from the reference values in autonomous mode as part of the developed navigation complex of mobile land objects of a particular purpose are analyzed. The preferable inertial meter for use in the developed TLNS was determined based on the research carried out.Practical implications. Recommendations are given on the use of SINS as an integral part at the facilities of the proposed base.
Ensinando Fronteiras: projetos estatais, representações sociais e interculturalidade
Authors: Filizola Roberto , Mokwa Félix Julian
Published: April 2021

Ensinando Fronteiras: projetos estatais, representações sociais e interculturalidade. Seu propósito e o público a que se destina espelham o encontro da fronteira com a educação em todos os níveis, desde a educação infantil até a pós-graduação. Os textos reunidos documentam a busca de alinhamentos para cultivar a esperança em tempos e espaços melhores de se viver, e demonstram a potência dos atributos da escola na direção do acolhimento, do cuidado e do crescimento intelectual e cidadão.
Królikarnia – muzeum dostępne
Authors: Zych-Charaziak Dorota
Published: April 2021

Artykuł jest próbą analizy działalności instytucji muzealnych, ich ewolucji i roli, jaką pełniły na przestrzeni dziejów. Porusza zagadnienia dotyczące ich pierwotnych założeń sięgających czasów starożytnych, aż po współczesne – przełamujące stereotypowe struktury, formy i funkcje tych instytucji. Pragnę zaakcentować w nim potrzebę ustawicznego edukowania społeczeństwa na takim poziomie, by mogło ono przyswajać ambitną ofertę, którą kierują do nas jednostki muzealne, a jednocześnie przybliżyć aspekt nowatorskich projektów skierowanych do wąskich grup osób dysfunkcyjnych. Inspiracją stała się dla mnie działalność Muzeum Królikarnia, będącego filią Muzeum Narodowego w Warszawie.
Element szczególny w otoczeniu – ślady Rotunda romańska na Wzgórzu Tumskim w Płocku
Authors: Markowski Sławomir Paweł
Published: April 2021

Od zarania cywilizacji człowiek – homo constructor – intuicyjnie dąży do przekształcania swego otoczenia oraz porządkowania go według sobie znanego sensu, w sposób bardziej lub miej trwały. W tej działalności nie tylko wielkie budowle, ale nawet te najmniej trwałe człowiecze dzieła, stają się w pewnej przestrzeni czasowej śladem – sygnum twórczych działań. Artykuł zawiera rys historyczny romańskiej rotundy – szczególnego elementu w przestrzeni krajobrazu kulturowego Wzgórza Tumskiego w Płocku, która pozostaje nie tylko jako ślad w płaszczyźnie programowej tego miejsca, ale dziś jest rzeczywistym śladem – symbolicznie zaznaczonym miejscem jej istnienia. Jest to jeden z tych śladów, który raz, że spełnia oczywistość historyczną, a dwa – staje się ekspozycją elementu szczególnego w krajobrazie.
W kontekście 100-lecia niepodległości Polski Mazowsze i jego gospodarka: od Drugiej do Trzeciej Rzeczypospolitej Część pierwsza: Druga Rzeczpospolita
Authors: Leszczyńska Cecylia
Published: April 2021

Niniejszy artykuł stanowi pierwszą część opracowania dotyczącego gospodarki Mazowsza na przestrzeni minionego stulecia. Przedstawia procesy i zjawiska, które ukształtowały i zdeterminowały strukturę gospodarki regionu w okresie Drugiej Rzeczypospolitej ze wskazaniem historycznego dziedzictwa, w szczególności procesów industrializacyjno-modernizacyjnych z końca XIX w., które miały fundamentalny wpływ na strukturę gospodarki Mazowsza w okresie międzywojennym. Część druga opracowania, dotycząca drugiej połowy XX w. i czasów współczesnych, ukaże się w jednym z następnych numerów czasopisma. Zostanie w niej zwrócona uwaga przede wszystkim na okres transformacji po 1989 r., w tym na dwudziestolecie 1998–2018, kiedy wpływ na gospodarkę regionu i kierunki jej rozwoju miały władze samorządowe województwa mazowieckiego.
Działalność Mazowieckiego Biura Planowania Regionalnego na rzecz rozwoju województwa mazowieckiego – efekty w subregionie siedleckim
Authors: Gadomska Urszula
Published: April 2021

Artykuł przedstawia wybrane zadania Mazowieckiego Biura Planowania Regionalnego (MBPR), których realizacja miała znaczący wpływ na rozwój subregionu siedleckiego. Biuro od 20 lat realizuje obowiązki samorządu Województwa Mazowieckiego w zakresie polityki rozwoju i zagospodarowania przestrzennego. Opracowywane w Biurze, szeroko uspołeczniane dokumenty strategiczne i opracowania analityczno-studialne, pozwoliły na jak najlepsze uwzględnienie specyfiki poszczególnych obszarów Mazowsza w polityce rozwoju regionu, prowadzonej przez jego władze. Władze, a efektami na obszarach słabo rozwiniętych, w tym w subregionie siedleckim, były m.in. preferencje w dofinansowywaniu projektów ze środków Unii Europejskiej (UE) w ramach kolejnych edycji Regionalnego Programu Operacyjnego Województwa Mazowieckiego (RPOWM). Bardzo ważnym aspektem polityki rozwoju regionu jest także wspieranie współpracy samorządów różnych poziomów w realizacji zadań o znaczeniu ponadlokalnym. W ostatnich latach, w wyniku współdziałania jednostek samorządu województwa, w tym MBPR, z samorządami lokalnymi, powstały zintegrowane plany inwestycyjne w poszczególnych obszarach Mazowsza, m.in. w subregionie siedleckim. Ich realizacja przebiega przy dofinansowaniu z RPOWM 2014–2020 w ramach specjalnego instrumentu wsparcia pod nazwą Regionalne Inwestycje Terytorialne.
Historyczne obiekty sportowe Warszawy jako walor turystyki współczesnej Część druga: po zakończeniu II wojny światowej
Authors: Pawlikowska-Piechotka Anna , Piechotka Maciej
Published: April 2021

Zaprezentowane w części pierwszej i drugiej artykułu warszawskie historyczne obiekty sportowe, z których najstarsze przetrwałe liczą sobie ponad 200 lat – stanowią istotny czynnik więzi społecznej. Zabytkowa architektura sportowa, tak jak i inne gmachy publiczne o walorach historycznych, są ponadto wizualnym spoiwem między tradycyjną tkanką miasta a współczesnością. Zgodnie z zasadami rozwoju zrównoważonego miast, przestrzeń publiczna i obiekty publiczne, w tym współczesne i historyczne obiekty sportowe, powinny pełnić znacznie szerszą i ważniejszą rolę społeczną niż przyjęło się tradycyjnie. W odniesieniu do obiektów i terenów sportowych, byłaby to poza główną funkcją sportową także edukacyjna, rekreacyjna i kulturotwórcza. Konsekwentnie obiekty sportowe powinny być wykorzystane dla różnych form turystyki, na przykład: sportowej, jako uczestnictwo bierne (kibice) i czynne (zawodnicy) w wydarzeniach sportowych, kongresowej, biznesowej, jako uczestnictwo w targach i wystawach, religijnej (spotkania duchowe), kulturowej przy wykorzystaniu obiektów i miejsc związanych z ważnymi sportowymi wydarzeniami o znaczeniu historycznym. Wydaje się, że w odniesieniu do warszawskich obiektów historycznych, przy ich planowym wykorzystaniu dla turystyki kulturowej i poznawczej, warto jest rozważyć zaprojektowanie szlaku tematycznego „Historyczne Obiekty Sportowe Warszawy”.
Estudos sobre os CEFFAS no Brasil
Authors: Araújo Sandra Regina Magalhães de
Published: April 2021

RESUMO

Este texto discute as produções acadêmicas que se dedicaram a investigar os Centros Educativos Familiares de Formação por Alternância (CEFFAs), entre os anos de 2006 a 2017. Desse modo, inicialmente tece breve considerações sobre as pesquisas na área da educação do campo; em seguida, mapeia por ano, regiões e instituições de ensino superior que ofertam cursos de pós-graduação e evidencia os estudos que tratam da pedagogia da alternância. Posteriormente, organizado por eixos temáticos, analisa as pesquisas sobre os CEFFAs, considerando entre outros aspectos, as diferentes abordagens de estudos. Nas considerações finais, chama atenção para o crescimento das pesquisas nas duas últimas décadas em torno da Educação do Campo, protagonizada pelas organizações sociais e sindicais do campo, entre as quais, o movimento educativo CEFFAs. Ressalta ainda a importância dessas pesquisas em diferentes áreas do conhecimento, com destaque para a de educação, por se tratar de uma alternativa diferenciada de educação do/no campo.
Desafios da formação docente no Programa Escola Da Terra
Authors: Santos Ramofly Bicalho , Estevam Suelen Pereira , Macedo Pedro Clei Sanches
Published: April 2021

O presente artigo tem como objetivo central apresentar reflexões acerca dos desafios da formação docente no Programa Escola da Terra, considerando as experiências pedagógicas desenvolvidas na UFRRJ – Universidade Federal Rural do Rio de Janeiro, na interface com as políticas públicas de educação do campo. Desenvolvemos uma pesquisa bibliográfica e documental, utilizando entre as fontes de investigação, legislações, portarias e decretos, assim como, referenciais teóricos sobre a educação do campo e o Programa Escola da Terra. Concluímos que a produção coletiva do saber, em parceria com os cursistas, equipe pedagógica, tutores, comunidades e os movimentos sociais de luta pela terra, contribuiu com a valorização das histórias, memórias, desejos e reconhecimento identitário dos sujeitos, individuais e coletivos, do campo, na sua estreita relação com as escolas do campo. Constatamos que essa articulação é um dos principais desafios a serem enfrentados pelo movimento da educação do campo no Brasil.
A Avaliação Educacional como Política Pública de Resistência
Authors: Araújo da Silva Roberto
Published: April 2021

O estudo analisa a atual política pública de avaliação da educação superior como meio de resistência ao conservadorismo. Apresenta o cenário da educação superior no país e explora aspectos da concepção, implementação e efeitos do SINAES (Sistema Nacional de Avaliação da Educação Superior). Elaborado como articulador entre a avaliação como regulação e a avaliação educativa, o Sistema sustenta-se como política de resistência, se consideradas as características formativas e indutoras de qualidade presentes em alguns de seus instrumentos avaliativos. De carátaer teórico-analítico, o trabalho vale-se do diálogo entre a literatura e os documentos sobre a temática como recurso hermenêutico. Conclui que o SINAES, como outras políticas públicas, passa por processo dinâmico de mudanças, porém permanece relevante como modo de repensar práticas no âmbito da educação superior.
O protagonismo dos Movimentos Sociais na experiência da Pós Graduação em Educação do Campo da UFRB
Authors: Lima Silvana Lúcia da Silva
Published: April 2021

A política pública de Educação do Campo é uma forma do Estado garantir o acesso a educação com suas espeficidades e, enquanto direito geral e universal. Para tanto, as universidades públicas foram convocadas a articular processos de produção do conhecimento socialmente comprometidos com a qualidade da reprodução social da vida camponesa. Nesse contexto, a UFRB passou a ofertar cursos de graduação e pós-graduação, entre eles o Mestrado em Educação do Campo que traz uma proposta conta hegemônica de formação que busca respostas técnico científicas para os dilemas e problemas enfrentados pelos povos do campo, em especial  no campo educativo.