bluuebunny/crossref_metadata_2025 huggingface dataset:
Alogliptin: a unique DPP-4 inhibitor that regulates adipose tissue insulin resistance and atherogenic lipids
Authors: Kutoh Eiji , Kuto Alexandra N , Ozawa Eri , Akiyama Midori , Kurihara Rumi
Published: January 2023

Objectives
This work is to investigate the regulation of adipose tissues insulin resistance with DPP-4 inhibitors in relation to other diabetic parameters in treatment naïve subjects with T2DM.
Methods
The subjects received alogliptin 12.5–25 mg/day (n = 55), sitagliptin 25–50 mg/day (n = 49) or teneligliptin 10–20 mg/day (n = 43) monotherapy for 3 months. Changes of adipo-IR and some diabetic parameters were analyzed.
Results
Among these drugs, only alogliptin could significantly reduce adipo-IR (-25.9%) and lipid parameters including LDL-C (-7.8%), T-C/HDL-C (-6.8%), log(TG)/HDL-C (-6.8%), non-HDL-C/HDL-C (-8.7%), LDL-C/HDL-C (-11.2%). The subjects in alogliptin group were divided into two similar numbers of groups with distinct changes (Δ) of adipo-IR (group A: Δadipo-IR=-56.5%, p < 0.00001, n = 28; group B: Δadipo-IR = 19.1%, p = 0.055, n = 27). Comparable, significant reductions of FBG (-14.1%, -15.5%) or HbA1c (10.26–8.93%, 11.04–9.08%) were observed in group A and B, respectively. Significant reductions of HOMA-R (-25.7%), T-C/HDL-C (-10.3%), TG (-18.1%), log(TG)/HDL-C (-11.3%), non-HDL-C/HDL-C (-13.1%), LDL-C/HDL-C (-12.8%) or FFA (-28.9%), and increases of QUICKI (5.9%) or HDL-C (6.9%) were seen in group A. By contrast, significant reductions of QUICKI (-3.8%) or LDL-C (-9.2%), and increases of HOMA-R (28.4%), insulin (55.1%), HOMA-B (106.3%), C-peptide (16.5%) or CPR-index (39.8%) were observed in group B.
Conclusion
These results indicate that 1) alogliptin, but not other DPP-4 inhibitors, could down-regulate adipo-IR and some atherogenic lipids. To date, this is the first report showing that a DPP-4 inhibitor regulates adipose tissue insulin resistance. 2) adipo-IR is associated with non-LDL-C lipid parameters, but not with glycemic control during treatment of alogliptin. 3) glycemic efficacy of alogliptin is determined by modulation of insulin resistance and beta-cell function.
Reinforcement learning-based design of shape-changing metamaterials
Authors: Oliva Sergi Bernaus , Bölle Felix Tim , Las A. T. , Xia Xiaoxing , Castelli Ivano
Published: January 2023

During the last decade, artificially architected materials have been designed to obtain properties unreachable by naturally occurring materials, whose properties are determined by their atomic structure and chemical composition. In this work, we implement a new reinforcement learning (RL) method able to design unique, rationally designed metamaterial structures at the nano-, micro-, and macroscale, which change shape during operational conditions. As an example, we apply this method to design nanostructured silicon anodes for Li-ion batteries (LIBs). The RL model is designed to apply different actions and predict change during operational conditions. The multi-component reward function comprises an increase in the total storage capacity of the resulting battery electrode and structural parameters, such as the minimum distance between the individual components of the nanostructure. Upon experimental validation using a polymer-based 3D printing technique, we expect that the newly discovered structures improve the current Si-based LIB anodes state-of-the-art by almost three times and almost ten times the current commercial LIB based on a graphitic anode. This RL-based optimization method opens up vast design space for other responsive metamaterials with tailored properties and pre-programmed structural transformation.
Isolation, Antibiotic Susceptibility Profile, and Associated Factors of Group B Streptococcus among Pregnant Women Attending Selected Health Institutions, Hawassa, Ethiopia, 2022
Authors: Adinew Alegntaw Abate , Mulatu Getamesay , Daka Deresse
Published: January 2023

Background: Globally, about 10-30% of the pregnant women were colonized with Group B Streptococcus in the genitourinary tract and 60% of their neonates were acquiring the infection during labor and delivery process.
Methods: A cross-sectional study was conducted among 329 pregnant women at 35th-37th gestational weeks from June 06-2022 to July 22-2022 at selected health institutions, in Hawassa, Ethiopia. Socio-demographic and clinical data were obtained by using a structured questionnaire. Group B Streptococcus was isolated from vagino-rectal swabs by using standard method recommended by Center of Disease Control and Prevention and an antibiotic susceptibility test was performed according to the Clinical and Laboratory Standards Institute guidelines. Data were analyzed by using SPSS version 25.0. Bivariate logistic regression was carried out and variables with p < 0.25 were selected for multivariate logistic regressions, p < 0.05 were accepted as statistically significant.
Results: The prevalence of Group B Streptococcus colonization among pregnant women at 35th-37th gestational weeks was 48/326 (14.7%; 95%CI: 10.8-18.5). The isolates that were developed resistance to Penicillin (2.1%), Ampicillin (4.2%), Erythromycin (8.3%), and Clindamycin (12.5%). Vancomycin showed (100%) sensitivity. Maternal GBS colonization were significantly associated with rural dwellers (AOR = 2.29 (95%CI = 1.17-5.32), p = 0.032) and who had one time ANC visit (AOR = 2.49 (95% CI = 1.07-4.93), p = 0.018).
Conclusion: There was a high frequency of GBS colonization, relatively low resistance to commonly used antibiotics, and significant association of maternal GBS colonization with rural dwellers and one time antenatal visit which suggests the screening of GBS colonization in pregnant women at 35th-37th weeks of gestation, testing their antimicrobial susceptibilities and encouraging antenatal fellow especially in rural dwellers in order to reduce maternal GBS colonization, provide antibiotic prophylaxis and minimize newborn infection and co-morbidity.
A multi-sensor wearable system for gait assessment in real-world conditions: performance in individuals with impaired mobility
Authors: Salis Francesca , Bertuletti Stefano , Bonci Tecla , Caruso Marco , Scott Kirsty , Alcock Lisa , Buckley Ellen , Gazit Eran , Hansen Clint , Schwickert Lars , Aminian Kamiar , Becker Clemens , Brown Philip , Carsin Anne-Elie , Caulfield Brian , Chiari Lorenzo , D'Ascanio Ilaria , Din Silvia Del , Eskofier Bjoern M. , Garcia-Aymerich Judith , Hausdorff Jeffrey M. , Hume Emily C. , Kirk Cameron , Kluge Felix , Koch Sarah , Kuederle Arne , Maetzler Walter , Micò-Amigo Encarna M. , Mueller Arne , Neatrour Isabel , Paraschiv-Ionescu Anisoara , Palmerini Luca , Yarnall Alison J. , Rochester Lynn , Sharrack Basil , Singleton David , Vereijken Beatrix , Vogiatzis Ioannis , Croce Ugo Della , Mazzà Claudia , Cereatti Andrea
Published: January 2023

Accurately assessing people’s gait, especially in real-world conditions and in case of impaired mobility, is still a challenge due to intrinsic and extrinsic factors resulting in gait complexity. To improve the estimation of gait-related digital mobility outcomes (DMOs) in real-world scenarios, this study presents a wearable multi-sensor system (INDIP), integrating complementary sensing approaches (two plantar pressure insoles, three inertial units and two distance sensors). The INDIP technical validity was assessed against stereophotogrammetry during a laboratory experimental protocol comprising structured tests (including continuous curvilinear and rectilinear walking and steps) and a simulation of daily-life activities (SDA, including intermittent gait and short walking bouts). To evaluate its performance on various gait patterns, data were collected on 128 participants from seven cohorts: healthy young and older adults, patients with Parkinson’s disease, multiple sclerosis, chronic obstructive pulmonary disease, congestive heart failure, and proximal femur fracture. Moreover, INDIP usability was evaluated by recording 2.5-hours of real-world unsupervised activity. Excellent absolute agreement (ICC > 0.95) and very limited mean absolute errors were observed for all cohorts and DMOs (cadence ≤ 0.61 steps/min, stride length ≤ 0.02 m, walking speed ≤ 0.02 m/s) in the structured tests. Larger, but limited, errors were observed during the SDA (cadence 2.72–4.87 steps/min, stride length 0.04–0.06 m, walking speed 0.03–0.05 m/s). Neither major technical nor usability issues were declared during the 2.5-hours acquisitions. Therefore, the INDIP system can be considered a valid and feasible solution to collect reference data for analyzing gait in real-world conditions.
The 249RWMD spike protein insertion in Omicron BQ.1 subvariant compensates the 24LPP and 69HV deletions and may cause severe disease than BF.7 and XBB.1 subvariants
Authors: CHAKRABORTY ASIT KUMAR
Published: January 2023

Alarming antibody evasion properties were documented for new BF, BQ and XBB Omicron subvariants. Most immune-drugs were inactive neutralizing those COVID-19 subvariants and viral titers were exceptionally low as compared to deadly B.1.1.7, B.1.617.2 and B.1.1.529 variants with D614G, N501Y and L452R mutations in spike. The 91% nucleotides changes in spike protein of BQ.1 were resulted in AA changes whereas only 52% nucleotides changes resulted in AAs changes in ORF1ab. The N460K and K444T mutations in BQ.1 may be important driving force for immune-escape similar to F486S and N480K mutations in BA.2.75 subvariant and related XBB.1 subvariant. Further, the R346T mutation as found in BA.4.6 and BF.7, was regained in BQ.1.1 and BA.2.75.2 to enhance immune escape and infectivity (> 80%). The L452R and F486V mutations in spike were main drivers of Omicron BA.2 conversion to BA.4 and BA.5 in presence of 69HV deletion. Whereas 24LPP spike deletion and 3675SGF ORF1ab protein deletion were found in all Omicron viruses including BQ.1 and XBB.1. Interestingly, we found about 211 COVID-19 sequences with four amino acids (249RWMD) insertion near the RBD domain of Omicron viruses similar to 215EPE three amino acids insertion in Omicron BA.1 variant. Such sequences first detected in California and extended to Florida, Washington and Michigan as well as other adjoining US states. An one amino acid deletion (140Y) in spike was also found in BA.4.6, BQ.1.5, BQ.1.8, BQ.1.14, BQ.1.1.5, XBB.1 as well as related AZ.3, BU.1, BW.1, CR.2, CP.1 and CQ.1 subvariants but was not detected in BA.2.75, BF.7, XBD, BQ.1, BQ.1.1, BQ.1.2, BQ.1.6, BQ.1.10, BQ.1.12, BQ.1.16, BQ.1.19, BQ.1.22, BQ.1.1.1, BQ.1.1.4, BQ.1.1.12 and related BK.1, BN.1, BM.1.1.1, BR.2, BU.1, CA.1, CD.2, CH.1.1 subvariants. Thus, BQ.1 insertion was compensated the other deletions and would be more infectious than BA.2.75, BF.7 and XBB.1 subvariants even there was a 26nt deletion in the 3’-UTR. The spike protein R341T one amino acid change in BQ.1.1 and BQ.1.1.1 might be important but no 249RWMD insertion.
Development of a reliability model for crack growth occurrence for a secondary hull component
Authors:   Norwegian University of Science and Technology, Department of Marine Technology, Jonsvannsveien 82, 7050 Trondheim, Norway, Kleivane Siri Kolle , Leira Bernt Johan , Steen Sverre
Published: January 2023

Ship hull vibration is a major contributor to fatigue crack growth and main engine excitation is identified as an important vibration source. A general method to solve any vibration problem arising onboard a ship does not exist, which encourages the use of a reliability-based framework for assessing ship vibration and its consequences. A stochastic model of vibration response is developed for the probabilistic formulation of the failure probability of the occurrence of crack propagation of a secondary structural hull component. The secondary structural component considered is a pipe stack support. The pipe stack support connects a cargo pump pipe stack to the wall inside the cargo tank, and the support is welded directly onto this wall. First, a generic cargo hold model is analysed with engine speed and the relative distance between the engine and the structural component under consideration as stochastic variables. Then, submodels are used to investigate the local vibration of the support and the stress response is evaluated for a combination of different engine speeds and relative distances. A surface is fitted to the vibration response and used for probabilistic analysis by Monte Carlo (MC/DSPS) and FORM/SORM reliability methods. The limit state is formulated as the possibility of fatigue crack growth based on a threshold stress intensity factor. This threshold factor depends on the initial crack size and different initial sizes are investigated. The adequacy of the functional representation for the stochastic model, which is fitted to discrete data points, is also assessed. It is seen that a functional representation using a sum of sine terms give an adequate fit for describing the stress response induced by engine speed, while a polynomial representation was adequate for the relative distance variable. The failure probability estimated by Monte Carlo simulations and SORM indicates that the pipe stack support is not critical for the occurrence of fatigue crack growth. A main observation from the analysis is that the reliability-based design of secondary structural components, also looking at the interaction with the global structure, may help to improve the vibration-induced stresses in local hull details by application of proper design measures.
Cheese as a food souvenir in Sicily
Authors: Fusté-Forné Francesc , Modica Federico , Sgroi Filippo
Published: January 2023

Souvenirs are elements of territorial communication, and they are examples of the marketing strategy of destinations. Souvenirs are objects that allow us to remember moments we have experienced and places we have visited. Drawing on the close relationships between places and souvenirs, this paper analyses cheese as a food souvenir in the island of Sicily. The method is based on a qualitative design which includes visits and interviews with local sellers in the food markets and food shops in Palermo, with the objective to reveal how cheese is protected and promoted as a symbol of Sicilian culture and heritage from a marketing perspective. Results of the paper show that cheeses made in Sicily are pivotal in the cheese marketing, while Italian cheeses also find their commercialization space. International cheeses are only available as styled cheeses also made in the country. Theoretical and practical implications are described.
Soil moisture monitoring by downscaling of remote sensing products using LST/VI space derived from MODIS products
Authors: Rostami Amin , Raeini-Sarjaz Mahmoud , Chabokpour Jafar , Chadee Aaron Anil
Published: January 2023

Soil moisture (SM) has an important role in the earth's water cycle and is a key variable in water resources management. Considering the critical state of water resources in the Urmia Lake basin, northwest Iran, this study examined the potential for utilizing a variety of remote sensing data and products, in conjunction with a promising downscaling method, to monitor soil moisture with a reasonable spatial and temporal resolution, as a novel and effective tool for agricultural and water resource management. Accordingly, remote sensing products of surface soil moisture were scaled to MODIS's image scale (∼1 km) using the UCLA downscaling method and Temperature, Vegetation, Drought Index (TVDI) values obtained from the scattering space method. Results showed that the LPRM, ESA-CCI, and GLDAS downscaled images had the highest inverse correlation with the TVDI (best results) accordingly equal to −0.600, −0.787, and −0.630. Also, based on the evaluation of the obtained results with the ground stations data, the LPRM and the ESA-CCI downscaled images had the best statistical indices values accordingly in 2010 and 2014 that confirm the promising application of remote sensing soil moisture data (rLPRM (2010) = 0.92, MAELPRM (2010) = 4.14%, RMSELPRM (2010) = 6.39% and rESA-CCI (2014) = 0.7, MAEESA-CCI (2014) = 2.23%, RMSEESA-CCI (2014) = 2.59%).
A Possível Competência do Tribunal Penal Internacional para Julgar Casos de Ecocídio no Brasil e as Inovações no Direito Internacional Ambiental
Authors: Oliveira Mayana Ribeiro , Fernandes Paula Jordana , Oliveira-Silva Iranse , Stival Mariane Morato
Published: January 2023

A ineficácia de medidas de responsabilização em caso de crimes ambientais que afetam o direito à vida, saúde e outros direitos fundamentais no cenário interno brasileiro, cabe ao Direito Internacional Ambiental apresentar possíveis alternativas no cenário internacional a fim de buscar meio de garantir medidas que tratem de uma maior proteção do meio ambiente, valor imprescindível. No Brasil, destaca-se nos últimos anos a ocorrência que tragédias socioambientais como o rompimento de barragens de mineração no Estado de Minas Gerais, o aumento das queimadas e desmatamento na Amazônia, a destruição de terras de comunidades ancestrais e indígenas, o aumento de problemas envolvendo danos ao meio ambiente nas cidades, o que tem levado à violação do direito à qualidade de vida das pessoas, dentre outros graves problemas e crimes ambientais. Neste contexto surge o movimento denominado Ecocídio, o qual representa os crimes e tragédias ambientais em grande escala. Assim, a presente pesquisa objetiva desenvolver uma análise sobre o Ecocídio no Brasil e as possíveis inovações sobre este tema no campo do Direito Internacional do Meio Ambiente. No campo metodológico, a pesquisa compreende um método de abordagem hipotético-dedutivo, com técnicas de pesquisa bibliográfica, na qual será utilizada a teoria e a legislação ambiental nacional e internacional envolvendo o Ecocídio e os principais documentos produzidos por órgãos internacionais como a Organização das Nações Unidas e relatórios do Tribunal Penal Internacional, órgão competente para o julgamento de casos de Ecocídio nos países que integram este sistema internacional. Considerando a relevância deste tribunal, será realizado um estudo sobre seus procedimentos e funcionamento. Neste sentido será verificada a possibilidade de se enquadrar tragédias ambientais ocorridas no Brasil, caracterizadas como Ecocídio a fim de se buscar a responsabilização internacional dos responsáveis pelos danos em tribunais internacionais, diante da baixa efetividade dos tribunais nacionais.
Transformação da Paisagem nas Serranias do Tinguá e Arredores da Baía de Guanabara: História Ambiental, Biodiversidade e Recursos Hídricos
Authors: Leitão Isabel Aparecida Custódio , Sales Gabriel Paes da Silva , Nunes Rafael da Silva , Guedes-Bruni Rejan R.
Published: January 2023

A paisagem do estado do Rio de Janeiro é constituída por extensas áreas de planícies, drenadas e permeadas por montanhas, como a Serra do Tinguá. Recoberta por Floresta Ombrófila Densa, assim como seus arredores, sua cobertura transfigura-se desde o século XVI: da agromanufatura açucareira até a expansão urbana contemporânea. O número de nascentes que ali se encontram contribui para algumas das principais bacias hidrográficas do estado, cujos mananciais são responsáveis pela configuração espacial histórica da área. Objetiva-se elaborar, à luz da história ambiental, um diagnóstico onde a Reserva Biológica do Tinguá (REBIO) constitui-se como elemento imperioso da paisagem, na oferta e configuração de vários serviços, especialmente à população da Baixada Fluminense. A avaliação da transformação da paisagem valeu-se de fontes documentais e bibliográficas, bem como de coleções de herbário disponíveis no INCT Herbário Virtual da Flora e dos Fungos. Atualmente, a cobertura florestal encontra-se reduzida a 44% no município de Nova Iguaçu. Considerando os últimos 35 anos, as terras utilizadas na agropecuária foram reduzidas a 29,66%, enquanto as edificadas aumentaram e totalizam 25,23%. O crescimento da população urbana e a fragilização dos mecanismos de fiscalização das áreas florestadas ameaçam a fauna e a flora locais, bem como as nascentes e os cursos d’água que compõem sua microbacia. A REBIO é responsável pela centralidade da região na produção e abastecimento d’água, além de outros serviços ambientais. O estudo reconhece a necessidade explícita de um olhar complexo sobre a paisagem, em sua perspectiva espaço-temporal. A compreensão dos elementos estruturais, assim como medidas estruturantes na paisagem, só é viável sob perspectivas múltiplas. Precipuamente sob este entendimento é possível elaborar diagnósticos, prognósticos e proposições orientados a ações de mitigação dos problemas ambientais, subsídios a políticas públicas e acesso ao patrimônio ambiental, cultural e histórico, que assegurem a promoção da qualidade de vida da sociedade.
Comunicación y Cambio Climático en la Prensa Argentina: Análisis a partir de un Evento de Sequía Extremo
Authors: León Leonardo Patricio Migues Vergilio de , Valginhak Débora , Romanini Emilio , Neves Frederico Monteiro
Published: January 2023

El cambio climático en la actualidad, consecuencia sobre todo de las actividades humanas, toma un importante destaque en el sector agropecuario. Por otro lado, la misma agropecuaria posee significativa dependencia a condiciones climáticas amenas y estables, siendo un sector vulnerable a los efectos del cambio climático (CC). En este escenario, los medios de comunicación se presentan como un mediador estratégico de las noticias producidas sobre dicha temática, contribuyendo no apenas para la formación de la opinión pública y tomada de decisión, como también, para la construcción de políticas públicas, por ser capaz de otorgarle visibilidad a los impactos resultantes. El objetivo del presente artículo es verificar si la sequía que impactó a la Argentina y que afectó la campaña de 2017/2018 fue relacionada al CC por la prensa nacional e identificar la forma en como el fenómeno fue transmitido por las mismos. Se utilizó el estudio documental, para la colecta de materiales de prensa publicados por los diarios La Nación, Chequeado y Clarín entre el periodo de 2017 y 2018, lo que resultó en 84 piezas periodísticas que fueron analizadas a través de técnicas de análisis de contenido. Entre los resultados se puede destacar que la mayor parte de las noticias no empleaba términos que comúnmente están asociados al CC, como mitigación, adaptación o resiliencia, además de centrar las discusiones en asuntos mayoritariamente económicos, lo que lleva a desconsiderar las causas estructurales que han contribuido para los propios efectos climáticos extremos sobre la agropecuaria y la sociedad.
Gobernanza y Prácticas Organizacionales Saludables de Tres Colegios de Chile y su Impacto en el Engagement y Burnout de sus Trabajadores
Authors: Acuña-Hormazabal Alvaro , Mendoza-Llanos Rodolfo , Luengo-Martínez Carolina , Ganga-Contreras Francisco
Published: January 2023

La rutina laboral de los trabajadores de la educación se ha visto modificada por la pandemia por COVID-19. Las transformaciones tecnológicas en la entrega del servicio educacional, han sido un factor extra de estrés. La adaptación a todos esto y bienestar de los trabajadores dependen en gran medida de la gobernanza y gestión que desarrollen los colegios. El objetivo central de este trabajo es estudiar la gobernanza de tres colegios de Chile, analizando la percepción de prácticas organizacionales saludables (POS) de los trabajadores y el impacto que tienen estas en el engagement y burnout. Para ello se realiza un análisis y comparación de la percepción de prácticas organizacionales saludables (POS) de los trabajadores de los colegios seleccionados. Se trata de una investigación con enfoque metodológico correlacional-explicativo. Para la obtención de la información, se aplicó un cuestionario a 231 trabajadores. Mediante la aplicación de ANOVA encontramos diferencias significativas entre los tres colegios para las prácticas organizacionales saludables, el engagement y el agotamiento emocional; Los trabajadores del colegio que tienen percepciones más altas de prácticas organizacionales saludables, también presentan puntuaciones mayores en engagement y menores en agotamiento emocional, lo que se corrobora al realizar las correlaciones entre las variables. Estos resultados instalan al colegio con mayores puntuaciones como una posible organización saludable.
REDESCRIPTION OF PUNCTORIBATES TSCHERNOVI SHTANCHAEVA AND SUBÍAS, 2014 (ACARI: ORIBATIDA: PUNCTORIBATIDAE)
Authors: Ermilov Sergey G. , Makarova O.L.
Published: January 2023

The redescription of Punctoribates tschernovi Shtanchaeva and Subías, 2014 (Oribatida: Punctoribatidae) is presented based on the material collected from the coastal grove of Elaeagnus caspica in the Samursky National Park, Dagestan, Russia. The main morphological traits of this species are specified and summarized.
NOTES ON SYSTEMATICS OF THE FEATHER MITE GENUS TROUESSARTIA CANESTRINI, 1899 (ACARIFORMES: TROUESSARTIIDAE) WITH AN UPDATED WORLD CHECKLIST
Authors: Mironov Sergey V.
Published: January 2023

The paper provides major references to Trouessartia species described since Santana’s (1976) world revision of this genus, unified diagnoses of 11 currently recognized species groups (africana, appendiculata, capensis, crucifera, estrildae, minutipes, picumni, rosterii, stelgidopteryx, tenuipilata and viduae), and a world checklist of currently known species. The updated checklist includes 147 valid species and is supplemented with data on type hosts, distribution and references to most useful descriptions.
Saudi EFL learners’ ability in literary and technical translation
Authors: Almuhailib Badar
Published: January 2023

Different perspectives invade our mind about the complexity level in translation attributed to text types. A translator may perform better in one type of text in comparison to other text types. This study probed the translation ability of Saudi EFL students in two text types. It also explored whether the participants scored differently in literary or technical text types. Finally, the study measured the correlation between the students' performance in the two text types. A translation test was used to collect data from the Saudi students enrolling at the English language and translation department at Qassim University.  Seven students' answers were analyzed and scored out of a maximum score of 24. Findings showed that Saudi EFL students achieve up to 75.70% in the translation of the two text types. Results also showed that there was no difference between students' translation ability attributed to text type (Sig. =.79), though individual performance showed better output in technical translation. Finally, the study indicated the existence of high correlation between students' scores in the literary and technical translation (R=.867*). The study concluded with recommending more investigation to refute the claim that students' translation ability differs across text types.
Undergraduate students’ perceptions of teachers’ written feedback in academic writing class: A survey study
Authors: Cahyani Nisa , Murtafi'ah Banatul
Published: January 2023

This survey study aims to describe the students’ perception of teachers’ written feedback in an academic writing class in a private university in Indonesia. 119 students filled in the questionnaire on students’ perceptions of teachers’ written feedback adapted from Ouahidi and Lamkhanter (2020). A descriptive statistic measuring mean, frequency, and standard deviation were used to analyze the data from the questionnaire. The results showed that the teacher’s written feedback to the writing results in the academic writing class was useful and students did not find it difficult to understand any feedback given by the teacher. Most of the students answered often when being asked about their understanding to the feedback. Students were also able to use teacher comments to revise their writing. Revision and rewriting were also found as the follow-up activities that are most often done by students after receiving feedback. Then, it was also revealed that students preferred their teacher to give them correction with comments to all the major errors in their writing. In addition to the feedback, students also preferred their teachers to give praise and criticism. Regarding the correction of students' writing work, students preferred the teacher to correct the errors in content or ideas. Further implications and suggestions are also discussed in this article.
use of icebreakers and games for interactive online learning
Authors: Felani Herman
Published: January 2023

The COVID-19 pandemic has been affecting the teaching-learning process in all levels of education, including in higher education. The implementation of online teaching-learning process has been inevitable in the effort to reduce the people to people contact and to prevent the spread of the virus. However, there have been complaints that the interaction quality during online class or meeting is lacking of warm and meaningful communication between the participants and the teachers. This research aims to implement and evaluate some ice breaking and games during online meetings to achieve an interactive learning with the good communication quality between participants of online classes. This qualitative research used the approach of action research. The results indicated that the implementation of ice breaking and improvement of interaction has been positively perceived by the participants. Thus, using proper ice breaking and games during online meetings is suggested.
Transformer-Based Neural Network Machine Translation Model for the Kurdish Sorani Dialect
Authors: Badawi Soran
Published: January 2023

The transformer model is one of the most recently developed models for translating texts into another language. The model uses the principle of attention mechanism, surpassing previous models, such as sequence-to-sequence, in terms of performance. It performed well with highly resourced English, French, and German languages. Using the model architecture, we investigate training the modified version of the model in a low-resourced language such as the Kurdish language. This paper presents the first-ever transformer-based neural machine translation model for the Kurdish language by utilizing vocabulary dictionary units that share vocabulary across the dataset. For this purpose, we combine all the existing parallel corpora of Kurdish – English by building a large corpus and training it on the proposed transformer model. The outcome indicated that the suggested transformer model works well with Kurdish texts by scoring (0.45) on bilingual evaluation understudy (BLEU). According to the BLEU standard, the score indicates a high-quality translation.
Technology-Enabled Collaborative Care for Concurrent Diabetes and Distress Management During the COVID-19 Pandemic: Protocol for a Mixed Methods Feasibility Study
Authors: Vojtila Lenka , Sherifali Diana , Dragonetti Rosa , Ashfaq Iqra , Veldhuizen Scott , Naeem Farooq , Agarwal Sri Mahavir , Melamed Osnat C , Crawford Allison , Gerretsen Philip , Hahn Margaret , Hill Sean , Kidd Sean , Mulsant Benoit , Serhal Eva , Tackaberry-Giddens Leah , Whitmore Carly , Marttila Jennifer , Tang Frank , Ramdass Seeta , Lourido Gloria , Sockalingam Sanjeev , Selby Peter
Published: January 2023

Background

The COVID-19 pandemic disrupted the delivery of diabetes care and worsened mental health among many patients with type 2 diabetes (T2D). This disruption puts patients with T2D at risk for poor diabetes outcomes, especially those who experience social disadvantage due to socioeconomic class, rurality, or ethnicity. The appropriate use of communication technology could reduce these gaps in diabetes care created by the pandemic and also provide support for psychological distress.

Objective

The purpose of this study is to test the feasibility of an innovative co-designed Technology-Enabled Collaborative Care (TECC) model for diabetes management and mental health support among adults with T2D.

Methods

We will recruit 30 adults with T2D residing in Ontario, Canada, to participate in our sequential explanatory mixed methods study. They will participate in 8 weekly web-based health coaching sessions with a registered nurse, who is a certified diabetes educator, who will be supported by a digital care team (ie, a peer mentor, an addictions specialist, a dietitian, a psychiatrist, and a psychotherapist). Assessments will be completed at baseline, 4 weeks, and 8 weeks, with a 12-week follow-up. Our primary outcome is the feasibility and acceptability of the intervention, as evident by the participant recruitment and retention rates. Key secondary outcomes include assessment completion and delivery of the intervention. Exploratory outcomes consist of changes in mental health, substance use, and physical health behaviors. Stakeholder experience and satisfaction will be explored through a qualitative descriptive study using one-on-one interviews.

Results

This paper describes the protocol of the study. The recruitment commenced in June 2021. This study was registered on October 29, 2020, on ClinicalTrials.gov (Registry ID: NCT04607915). As of June 2022, all participants have been recruited. It is anticipated that data analysis will be complete by the end of 2022, with study findings available by the end of 2023.

Conclusions

The development of an innovative, technology-enabled model will provide necessary support for individuals living with T2D and mental health challenges. This TECC program will determine the feasibility of TECC for patients with T2D and mental health issues.

Trial Registration

ClinicalTrials.gov NCT04607915; https://clinicaltrials.gov/ct2/show/NCT04607915

International Registered Report Identifier (IRRID)

DERR1-10.2196/39724
Study protocol: transurethral REsection and Single instillation intravesical chemotherapy Evaluation in bladder Cancer Treatment (RESECT). A multi-centre international observational study with embedded cluster randomised trial of audit, feedback and education. (Preprint)
Authors: Gallagher Kevin , Bhatt Nikita , Clement Keiran , Zimmermann Eleanor , Khadhouri Sinan , MacLennan Steven , Kulkarni Meghana , Gaba Fortis , Anbarasan Thines , Asif Aqua , Light Alexander , Ng Alexander , Chan Vinson , Nathan Arjun , Cooper David , Aucott Lorna , Marcq Gautier , TEOH Jeremy Yuen-Chun , Hensley Patrick , Duncan Eilidh , Goulao Beatrice , O'Brien Tim , Nielsen Matthew , Mariappan Paramananthan , Kasivisvanathan Veeru
Published: January 2023

BACKGROUND

Non-muscle invasive bladder cancer (NMIBC) accounts for 75% of bladder cancers. It is common and costly. Cost and detriment to patient outcomes and quality of life are driven by high recurrence rates and the need for regular invasive surveillance with frequent repeat treatments. There is evidence that the quality of the initial surgical procedure (Transurethral resection of bladder tumour (TURBT)) and timely administration of postoperative bladder chemotherapy significantly reduces cancer recurrence rates and improves outcomes such as cancer progression and mortality. There is some survey-based evidence that TURBT practice varies significantly across surgeons and sites1. There is evidence from clinical trials that NMIBC recurrence rate varies significantly between sites and that this cannot be accounted for by differences in patient, tumour, or adjuvant treatment factors, suggesting that how the surgery is performed may be a reason for the variation.

OBJECTIVE

This study primarily aims to determine if feedback of and education about surgical quality indicators can improve performance, and secondarily if this can reduce cancer recurrence rates.

METHODS

This study is an observational, international, multi-centre study with an embedded cluster randomised trial of audit, feedback, and education.
Sites will be included if they perform TURBT for NMIBC.

RESULTS

The study has 4 co-primary outcomes which are 4 TURBT quality indicators: a surgical performance factor; an adjuvant treatment factor; and two documentation factors. A key secondary outcome is the early cancer recurrence rate.

CONCLUSIONS

Local and/or national ethical and institutional approvals or exemptions will be obtained at each participating site. The study results will be published in peer-reviewed journals and presented at national and international scientific congresses.

CLINICALTRIAL

The study is registered with clinicaltrials.org (NCT05154084).
Por que ainda insisto na terapia comunitária? Relato de uma experiência formativa e prática
Authors: Santos Rosangela Gomes dos , Lima Maria Raquel da Silva , Maia Ítala Maria de Queiroz , Guidetti Erika
Published: January 2023

A Terapia Comunitária Integrativa valoriza as histórias de vida dos participantes, o resgate da identidade, a restauração da autoestima e da confiança em si e a ampliação da percepção dos problemas e das possibilidades de resolução a partir das competências locais, ou seja, torna o indivíduo mais autônomo e independente. O objetivo deste estudo foi descrever a experiência formativa e a prática da Terapia Comunitária Integrativa. Trata-se de um relato desenvolvido em duas Unidades Primárias de Atenção à Saúde no município de Horizonte, estado do Ceará. Este trabalho teve início a partir da proposta formativa lançada pela Residência Integrada em Saúde da Escola de Saúde Pública do Ceará. A equipe de terapeutas residentes foi composta por três profissionais: uma assistente social, uma cirurgiã-dentista e uma educadora física. As rodas terapêuticas ocorreram em duas unidades de saúde. Um dos desafios que mais persistiu foi a mobilização da comunidade, pois foi observada, durante todo o processo, a variação do público participante, no que diz respeito ao gênero, à idade e ao papel desenvolvido na comunidade. A equipe valorizou o vínculo, tecendo redes de acesso, disponibilizando-se enquanto equipe de terapeutas e demonstrando a importância do cuidado que vai além da clínica. Foi proposta outra forma de cuidado, que valoriza a autonomia do sujeito e sua capacidade, lembrando sempre que há uma identidade na comunidade e que juntos somos mais fortes.
Adolescentes rurais: comportamento de risco para excesso de peso e aumento da circunferência da cintura
Authors: Oliveira Victor Vieira de , Araújo Marilia de Souza , Lima Laís do Espírito Santo
Published: January 2023

Este estudo tem como objetivo investigar os fatores sociodemográficos, econômicos e comportamentais associados ao excesso de peso e aumento da circunferência da cintura em adolescentes cursando o ensino médio em comunidades rurais. Trata-se de estudo epidemiológico, transversal e observacional. As informações foram coletadas por meio de versão adaptada do questionário da Pesquisa Nacional de Saúde do Escolar, proposto pelo Instituto Brasileiro de Geografia e Estatística (IBGE). Por meio da análise exploratória de dados e análise de regressão logística múltipla, foi possível estimar as razões de chances brutas e ajustadas e seus respectivos intervalos de confiança de 95%. O excesso de peso corporal mostrou associações significativas com o sexo masculino (p = 0,042), faixa etária (p = <0,003), baixa escolaridade materna (p = 0,018) e aumento da circunferência da cintura (p = <0.001). Já a elevação da circunferência da cintura (CC) mostrou-se também associada ao sexo masculino (p = 0,033), à baixa escolaridade materna (p = 0,016) e à quantidade de banheiros com chuveiro por domicílio (p = 0,025). Ser do sexo masculino mostrou-se como fator de proteção para o excesso de peso e obesidade abdominal, e as piores condições socioeconômicas mostraram-se associadas ao aumento de risco cardiovascular nessa população.
Produção científica sobre as políticas governamentais direcionadas à saúde da população negra
Authors: Ribeiro Anaira Gisser Sousa , Slob Edna Marcia Grahl Brandalize
Published: January 2023

Objetivou-se descrever a produção científica acerca das políticas, estratégias e ações governamentais direcionadas à saúde da população negra. Conduziu-se uma revisão integrativa da literatura nas bases de dados da Biblioteca Virtual de Saúde (BVS), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (SciELO), sites governamentais, legislações vigentes e revistas eletrônicas. Utilizaram-se os descritores “política de saúde”, “saúde pública”, “negro” e “população negra”, com o auxílio dos operadores booleanos. Percebe-se, na sociedade, que o negro convive com situações de discriminações, preconceitos, desigualdades, vulnerabilidades e vários tipos de exclusão. É nesse cenário que programas, projetos e ações na área da saúde foram criados na tentativa de amenizar os impactos sofridos por essa população. Assim, foram identificadas 11 estratégias, ações ou políticas governamentais, entre os anos de 2004 e 2017, direcionadas à saúde da população negra. A produção científica sobre as políticas, estratégias e ações governamentais está em evolução; ressalta-se que esse processo é assistemático e sofre influência do engajamento social pelo assunto, no entanto, há dificuldades e barreiras que limitam a materialização dessas medidas.
Relato da implantação do matriciamento em um município cearense: dos desafios às conquistas
Authors: Sousa Paulo Henrique Caetano de , Azevedo Uly Castro de , Monteiro Marianna Braga Noronha , Silva Pamela Bezerra da
Published: January 2023

O apoio matricial constitui uma das prerrogativas básicas para o acompanhamento longitudinal, holístico e eficaz de casos complexos das comunidades, sendo essa a base de sustentação do Núcleo Ampliado de Saúde da Família e Atenção Básica (Nasf-AB), hoje chamado de equipe multiprofissional em saúde. O objetivo deste artigo foi descrever como ocorreu o processo de implantação das reuniões de matriciamento em um Nasf municipal do interior cearense, por meio de um relato de experiência qualitativo, transversal, narrativo-descritivo e com base na vivência de instituição da reunião de matriciamento. Foram utilizados registros escritos das atas de reunião e os eventos memoráveis. O processo de instituição das reuniões de matriciamento se deu em três etapas: análise territorial, na qual foram levantados os problemas da comunidade, bem como identificadas as redes disponíveis no município; reunião de esclarecimento sobre a ideia do apoio matricial, benefícios e maneiras de sua implantação na rotina profissional (nessa etapa, além da conscientização dos profissionais, buscou-se o apoio da gestão); e pactuação acerca das frequências em que os encontros se realizariam, tomando por base reuniões de maneira sequencial e seleção dos casos que seriam discutidos. Foi concluído que, para que se realizem de maneira eficaz, é necessário que as reuniões de matriciamento tenham objetivos esclarecidos diante dos profissionais que participarão delas, uma vez que muitos processos de trabalho não têm a ótica do apoio matricial. Porém, deve-se compreender que surgirão dificuldades na manutenção de tais encontros e que o sucesso ou fracasso das reuniões será responsabilidade de todos os participantes.
Perfil dos usuários e atendimento das Unidades Básicas de Saúde do município de Criciúma (SC)
Authors: Parode Tiago Canabarro , Gonçalves Renata C. , Meller Fernanda de Oliveira , Quadra Micaela Rabelo , Martins Carla Damasio , Schäfer Antônio Augusto
Published: January 2023

O objetivo deste estudo foi avaliar as características dos usuários e dos atendimentos realizados nas Unidades Básicas de Saúde do município de Criciúma/SC. Foram avaliados todos atendimentos realizados no ano de 2018, através da coleta de dados secundários no sistema de informação em saúde (CELK Saúde) do município. As variáveis analisadas foram: idade, sexo, escolaridade, situação de moradia, encaminhamentos realizados à atenção secundária, classificação e tipos de atendimentos registrados durante as consultas e os principais procedimentos executados. Foram realizadas análises descritivas das variáveis estudadas, com a apresentação das frequências absolutas e relativas. Dentre os 452.605 atendimentos avaliados, observou-se que 64,57% dos atendimentos foram realizados pelo sexo feminino e pelos indivíduos com 60 anos ou mais. A maior prevalência de atendimentos foi na classificação saúde mental. Em relação aos tipos de atendimento, notou-se predominância de consulta médica em todos os distritos. Quanto aos encaminhados realizados à atenção secundária, os mais prevalentes foram a oftalmologia e a ortopedia. Os resultados encontrados neste estudo podem orientar os gestores em saúde no desenvolvimento de estratégias e alternativas de intervenções efetivas na atenção básica, melhorando a qualidade e otimizando os serviços públicos ofertados.
Relação entre o peso corporal e a insatisfação com a imagem corporal entre estudantes universitários
Authors: Oliveira Josué Souza Almeida , Girotto Edmarlon , Guidoni Camilo Molino
Published: January 2023

O Brasil vive uma epidemia de obesidade há muitos anos, situação que leva ao aumento do risco de doenças cardiovasculares. Entre os jovens, observa-se elevação de distúrbios da imagem corporal, sendo que um terço está insatisfeito com a própria aparência. Dessa forma, foi analisada a relação entre o peso corporal e a insatisfação com a imagem corporal entre estudantes universitários. Este é um estudo transversal realizado com 3.168 estudantes de uma universidade pública paranaense. Para avaliação da satisfação corporal, foi utilizado o Body Shape Questionnaire (BSQ) adaptado e validado para o Brasil. Para o peso corporal, foi utilizado o Índice de Massa Corpórea (IMC). Na análise de associação, foi utilizada Regressão de Poisson com variância robusta com cálculo da razão de prevalência (RP) e intervalo de confiança 95% (IC95%). Os resultados alcançados mostram que estudantes com sobrepeso (RP: 1,56; IC95% 1,46-1,67) e obesidade (RP: 1,68; IC95% 1,55-1,81) apresentaram maior insatisfação com a imagem corporal, independentemente das variáveis de ajuste. Já entre estudantes com baixo peso (RP: 0,42; IC95% 0,34-0,53), a insatisfação com a imagem corporal é menor. Independentemente de variáveis sociodemográficas e de saúde mental, estudantes universitários com excesso de peso constituem um grupo com maior prevalência para a insatisfação corporal.
Qualidade de vida de acadêmicos que se deslocam para uma universidade particular em Sergipe
Authors: Santos Jeferson dos , Barreto Thainá Sthephany Silveira , Passos Taciana Silveira , Costa da Cunha Oliveira Cristiane
Published: January 2023

No decorrer da graduação, os universitários sofrem pressões biopsicossociais que comprometem não só sua qualidade de vida (QV), mas também o desempenho nas mais variadas circunstâncias. O objetivo deste estudo foi analisar a QV dos universitários de Tobias Barreto (SE) que se deslocavam para a Universidade Tiradentes em Aracaju (SE) no primeiro semestre de 2018. Para isso, foi realizado um estudo de natureza quantitativa, do tipo corte transversal, com moradores universitários do município de Tobias Barreto que se deslocavam para a capital Aracaju para estudar, no primeiro semestre de 2018, tendo como amostra 97 acadêmicos. A maioria dos participantes eram do sexo masculino, cor parda e residiam em Tobias Barreto. Desses, 94,85% moravam em casa própria e 42,27% recebiam até um salário mínimo proveniente de atividade remunerada – enquadravam-se na classe C1. Mesmo diante das dificuldades vivenciadas diariamente, os universitários apresentaram um bom rendimento acadêmico e um escore melhor de qualidade de vida no domínio social, e um escore menor no domínio ambiental.