bluuebunny/crossref_metadata_2025 huggingface dataset:
An Assessment of the Effects of Azodicarbonamide-containing Diet on Neurobehaviour, Brain Antioxidant Status and Membrane Lipid Peroxidation Status in Rats
Authors: Olofinnade Anthony T. , Adeyeba Adegboyega , Onaolapo Adejoke Y. , Onaolapo Olakunle J.
Published: November 2019

Background:

Azodicarbonamide is a dough-enhancer used in the process of breadmaking
in countries like Nigeria. While there have been suggestions that it is a sensitizer of the
respiratory system, there is a dearth of information on its effects on the central nervous system.

Aim:

This study assessed the effects of azodicarbonamide on the central nervous system (ADA)
in rats.

Objective:

The effects of ADA-containing diet on neurobehaviour, brain antioxidant status, and
neuromorphology of selected brain regions in rats were examined.

Method:

Forty adult rats were randomly-assigned into four groups of ten rats each, and were
given standard diet or diet containing ADA at 1, 2 and 4% respectively. Rats were fed a standard
diet or ADA-containing diet for a period of 28 days. Weekly body weight assessment and daily
estimation of food intake were done. Behavioural tests in the Open field, Y-maze, radial-arm
maze, and Elevated Plus Maze (EPM) were conducted on day 29. Twenty-four hours after the
last behavioural test, animals were euthanised, whole brains were dissected, weighed, and either
homogenised for assessment of lipid peroxidation and antioxidant status; or sectioned and
processed for general histology.

Results :

Consumption of ADA-containing diet was associated with a significant decrease in
weight gain/food intake, and significant suppression of horizontal locomotion and rearing behaviours;
however, grooming activity increased significantly. Also, there was a significant reduction
of open-arm time in the EPM and a significant increase in Y-maze alternation (at the lowest concentration
of ADA). ADA-containing diet was not associated with significant changes in brain
oxidative status or neuromorphology.

Conclusion:

The study showed that while ADA-containing diet may alter neurobehaviour in rats;
this was not associated with evidence of brain oxidative stress or neuro-histomorphological
alterations.
Effect of Particle Size Distribution and Selective Alcohol Additives for Preparation of High Concentration Coal-Water Slurry
Authors: Das Debadutta , Routray Anupama , Pattanaik Swetashree , Parhi Pankaj K. , Das Bijnyan R. , Das Subrata N.
Published: November 2019

Background:

The alternative of oil is highly essential in the present context due to the acute shortage of oil as well as increasing demand for it from different public and private sectors. Since 1980, attention has been focused on coal-water slurry as an alternative fuel for the power generation industry and a suitable substitute for oil in several industrial applications. One of the exciting areas in Coal Water Slurry (CWS) is coal–water-alcohol slurry in which different alcohol compound can act as a dispersant for the stabilisation of coal–water slurry.

Objective:

The objective of this paper is to prepare a high concentration coal–water-alcohol slurry using glycerol, glycol and ethanol as an additive, and different particle size distribution of coal. This will increase the surface activity of the coal thereby, decreasing the viscosity of the slurry.

Method:

Two bimodal samples are prepared in which coarse particles are (212 μm - 300 μm), (150 μm – 212 μm) and fine particle below 75 μm. Three types of alcohol additive namely glycerol, glycol and ethanol are used as a dispersant. Malvern Particle size analyzer is used to measure the particle size distribution of the coal samples. Rheological study of CWAS was conducted using HAAKE RHEO STRESS 1.

Result:

From the experiment, it has been concluded that the optimum addition of glycerol in water is taken as 90:10 of water and glycerol ratio because after that, there is no further decrease in the value of viscosity. An optimum value of glycol and ethanol mixed in water was determined and found as in the ratio of 86:14 and 82:18, respectively.

Conclusion:

From different parameter studies like coal concentration, pH, temperature, apparent viscosity and stability, it has been concluded that coal-water-glycerol slurry is better than other coal water- alcohol slurry. This is because of the presence of more OH- groups in glycerol. The static stability of this coal-water-alcohol slurry exists for the maximum period of 31 days.
Oxaloacetate Mediates Mitochondrial Metabolism and Function
Authors: Yu Liping , Sivitz William I.
Published: November 2019

Oxaloacetate, an intermediate in the tricarboxylic acid cycle, plays important roles in regulating mitochondrial function, gluconeogenesis, the urea cycle, and amino acid syntheses. Because this compound is not stable, more information is needed about its stability profile before its medicinal potential can be realized. In this short review, we present current knowledge and understanding of oxaloacetate with a focus on its stability, degradation, quantification methods, regulation of mitochondrial function, and potential therapeutic benefits. Further, we report previously unpublished spectral data related to the stability profile of oxaloacetate. We found that oxaloacetate has a half-life of about 14 hours in biological aqueous solution at 25°C before degrading into pyruvate. This mandates careful attention to handling this compound including storage at -20 to -80°C when not in use to prolong its shelf-life. Also, the oxaloacetate stability profile needs to be taken into account when conducting experiments involving the compound either in clinical trials or evaluating it as a health supplement or for other experiments. Measuring oxaloacetate by mass-spectrometry requires cumbersome derivatization to assure stability. However, we found that NMR can be used to detect oxaloacetate quantitatively without the need for making derivatives, and the NMR method is sensitive enough to detect oxaloacetate in the micromolar range. Using this method, we showed that oxaloacetate regulates mitochondrial complex II-driven respiration by potent inhibition of succinate dehydrogenase. Moreover, a growing literature in the past few years suggests that oxaloacetate may have therapeutic benefits in treating a variety of diseases.
Design, Development and Optimization of Glibenclamide Sustained Release Matrix Tablet by Using Natural Polymers
Authors: Ramteke Kuldeep H. , Ghadge Dipika E. , Palve Savita A. , Gaikwad Sachin S.
Published: November 2019

Background:

Tablets being the conventional dosage forms can be modified for providing
the desired therapeutic effect to the patients. The network of matrix in the tablet allows the drug release
to be slowed down considerably.

Objective:

The prime objective of the study was to formulate sustained release glibenclamide matrix
tablets using locust bean gum and karaya gum as a matrix polymer.

Methods:

Tablets were formulated by optimization using 32 factorial designs by direct compression
method using different drug: polymer concentrations. The dependent variables selected were % cumulative
drug release (Y1) and % drug content (Y2). The independent variables are the amount of locust
bean gum (X1) and karayagum (X2). Drug-polymer compatibility studies were confirmed by
FTIR and DSC. The pre-compression properties of powder were assessed indicating a good flow
property. The evaluation results of the tablets were found to be within the Indian Pharmacopoeial
limit. In this work, the effect of diluents type and polymer type was studied on the drug release with
its increase in concentration.

Results:

All the formulations showed retarded drug release as the concentration of the polymer was
increased. Formulation F8 was selected as the best-optimized formulation with about 100.56% drug
release within 12 h. Release kinetics was carried out and it was found to be zero-order release and
from assay, drug content was found to be in limits.

Conclusion:

ANOVA analysis indicated that the studied variables affected the response variables
significantly. The optimized formulation was stable. Hence, it is concluded that the Glibenclamide
sustained release matrix tablet containing natural polymers were successfully formulated by using 32
factorial design.
HoloLens-Based Vascular Localization System: Precision Evaluation Study With a Three-Dimensional Printed Model (Preprint)
Authors: Jiang Taoran , Yu Dewang , Wang Yuqi , Zan Tao , Wang Shuyi , Li Qingfeng
Published: November 2019

BACKGROUND

Vascular localization is crucial for perforator flap transfer. Augmented reality offers a novel method to seamlessly combine real information with virtual objects created by computed tomographic angiography to help the surgeon “see through” the skin and precisely localize the perforator. The head-mounted display augmented reality system HoloLens (Microsoft) could facilitate augmented reality–based perforator localization for a more convenient and safe procedure.

OBJECTIVE

The aim of this study was to evaluate the precision of the HoloLens-based vascular localization system, as the most important performance indicator of a new localization system.

METHODS

The precision of the HoloLens-based vascular localization system was tested in a simulated operating room under different conditions with a three-dimensional (3D) printed model. The coordinates of five pairs of points on the vascular map that could be easily identified on the 3D printed model and virtual model were detected by a probe, and the distance between the corresponding points was calculated as the navigation error.

RESULTS

The mean errors were determined under different conditions, with a minimum error of 1.35 mm (SD 0.43) and maximum error of 3.18 mm (SD 1.32), which were within the clinically acceptable range. There were no significant differences in the errors obtained under different visual angles, different light intensities, or different states (static or motion). However, the error was larger when tested with light compared with that tested without light.

CONCLUSIONS

This precision evaluation demonstrated that the HoloLens system can precisely localize the perforator and potentially help the surgeon accomplish the operation. The authors recommend using HoloLens-based surgical navigation without light.
Cardiac rehabilitation in patients with refractory angina trial: rationale and design (Preprint)
Authors: Dourado Luciana , Jordão Camila , Assumpção Camila Regina , Montenegro Carla , Gowdak Luis Henrique , Vieira Marcelo Luiz , Pereira Alexandre , Cesar Luiz Antonio , Negrão Carlos Eduardo , De Matos Luciana
Published: November 2019

BACKGROUND

Refractory angina is a chronic condition that implies significant impairment in quality of life; its management is a challenge. Current therapies are limited, and new approaches to treatment are needed that target symptoms and quality of life. Evidence is lacking regarding exercise-based cardiac rehabilitation safety and beneficial effects in patients with refractory angina.

OBJECTIVE

The aim of the present study is to evaluate the safety and feasibility of exercise-based cardiac rehabilitation in patients with refractory angina, and its effects on angina symptoms, functional capacity, and ischemic burden.

METHODS

This study is an ongoing prospective randomized controlled trial enrolling 52 patients with refractory angina randomized into 2 groups: optimal medical treatment (MT) or MT + exercise-based cardiac rehabilitation (CR) over 12 weeks (36 exercise sessions). Clinical evaluation, cardiopulmonary exercise testing, laboratory tests, and exercise echocardiography are performed before and after intervention. The CR group performs in-hospital exercise sessions. The aerobic training protocol is based on CPT parameters or ischemia/angina threshold. Each cardiac rehabilitation session is 60 minutes long (5 minutes of warm-up, 30 minutes of continuous aerobic exercise based on target heart rate corresponding to anaerobic threshold (AT) obtained in the cardiopulmonary exercise testing OR angina/ischemia threshold if it occurs before the AT, 5 minutes of cooling-down, 15 minutes of resistance training, and 5 minutes of stretching).

RESULTS

This research study is in progress, with 42 patients recruited as of August 2019. Data collection is expected to be finished before December 2020. No clinical adverse events related to CR have occurred.

CONCLUSIONS

The findings of this study will have important clinical implications in the treatment of refractory angina patients.

CLINICALTRIAL

NCT03218891
PREVALENCE AND FACTORS ASSOCIATED WITH EARLY MARRIAGE IN CHIPULUKUSU TOWNSHIP OF NDOLA, ZAMBIA:cross sectional study (Preprint)
Authors: Banda Satiel
Published: November 2019

BACKGROUND

In the statistics taken from media brief on ending child marriage in Zambia, (2014) states, “Zambia is the third highest country with cases of child marriages in the SADC region and 19th in the world. In Zambia, about 42 per cent of women aged 20-24 years are married by the age of 18 – a rate that has not evolved since 2002. The rates of child marriages vary from province to province, and are as high as 60 per cent in the Eastern Province. (www.girlsnotbrides.org.) accessed on 20th November 2014. At 13.42) The ZDHS [Zambia Demographic Health Survey] indicates that among married girls aged 15-19 in Zambia, 68 percent have already given birth. In addition, most of the births occurring to girls before age 18 are first births (85 percent), and a majority of these first births occur within marriage. A Central Statistical Office (CSO) report of 2010 carried out by Plan Zambia indicates that “only a few adolescent girls and boys complete upper primary education while the enrolment ratio in secondary education is 13.4% for males and 12.9% for females.” The report concludes that child marriage is the critical driver for this state of affairs.

OBJECTIVE

This study is aimed at determining the prevalence and factors associated with child marriage in Chipulukusu township of Ndola. Zambia.

METHODS

A cross-sectional study was conducted in Chipulukusu Township within the location of Ndola. A pretest questionnaire was used to collect information on child marriage prevalence and factors towards the practice of child marriage and other relevant socio-demographic characteristics.

RESULTS

the prevalence of early marriage in Chipulukusu township of Ndola district, Zambia was 20.7 % with it being significantly associated with lower social economic status (poverty), lower education level, orphanhood and teen pregnancies

CONCLUSIONS

the prevalence of early marriage in this study was high. Its prevalence was significantly associated with people of poor backgrounds (poverty), teen pregnancies, lower education level, and orphan hood.
Identifying Acute Low Back Pain Episodes in Primary Care Practice From Clinical Notes: Observational Study (Preprint)
Authors: Miotto Riccardo , Percha Bethany L , Glicksberg Benjamin S , Lee Hao-Chih , Cruz Lisanne , Dudley Joel T , Nabeel Ismail
Published: November 2019

BACKGROUND

Acute and chronic low back pain (LBP) are different conditions with different treatments. However, they are coded in electronic health records with the same International Classification of Diseases, 10th revision (ICD-10) code (M54.5) and can be differentiated only by retrospective chart reviews. This prevents an efficient definition of data-driven guidelines for billing and therapy recommendations, such as return-to-work options.

OBJECTIVE

The objective of this study was to evaluate the feasibility of automatically distinguishing acute LBP episodes by analyzing free-text clinical notes.

METHODS

We used a dataset of 17,409 clinical notes from different primary care practices; of these, 891 documents were manually annotated as acute LBP and 2973 were generally associated with LBP via the recorded ICD-10 code. We compared different supervised and unsupervised strategies for automated identification: keyword search, topic modeling, logistic regression with bag of n-grams and manual features, and deep learning (a convolutional neural network-based architecture [ConvNet]). We trained the supervised models using either manual annotations or ICD-10 codes as positive labels.

RESULTS

ConvNet trained using manual annotations obtained the best results with an area under the receiver operating characteristic curve of 0.98 and an F score of 0.70. ConvNet’s results were also robust to reduction of the number of manually annotated documents. In the absence of manual annotations, topic models performed better than methods trained using ICD-10 codes, which were unsatisfactory for identifying LBP acuity.

CONCLUSIONS

This study uses clinical notes to delineate a potential path toward systematic learning of therapeutic strategies, billing guidelines, and management options for acute LBP at the point of care.
Oxidation of Oven-Dried Cassava Starch Using Hydrogen Peroxide and UV-C Irradiation to Improve Frying Expansion
Authors: Muflihati Iffah , Marseno Djagal Wiseso , Pranoto Yudi
Published: November 2019

Native cassava starch usually has low volume expansion. Some modifications were developed to change its physical and chemical characteristic, i.e. hydrogen peroxide addition and UV-C irradiation. The objectives of this study were to determine UV-C intensity, oxidation time, and concentration of hydrogen peroxide addition which resulted in the highest frying expansion of oven-dried cassava starch. Oxidation was conducted with acidification of cassava starch using 1% (w/w) lactic acid, the addition of hydrogen peroxide, and irradiation of UV-C in a tumbler. Combination of UV-C intensity, oxidation time, and hydrogen peroxide concentration were adjusted by Box-Behnken design. Optimization of cassava starch was determined by Response Surface Methodology (RSM), with frying expansion as a main response. Oxidized cassava starch was analyzed for physical and chemical characteristics. The result of this study showed that the oxidation of cassava starch increased the frying expansion, carbonyl and carboxyl content, amylose content, solubility, and decreased the swelling power. The optimum condition of oven-dried cassava starch oxidation was reached at 40 -watt UV-C intensity, oxidation time 2,281 minutes, and hydrogen peroxide concentration 1% (w/w), with the percentage of frying expansion 347,26%.
The Efficacy Study of Duramectin, Oxfendazole, Piperazine, and Pyrantel pamoate Against Gastrointestinal Worms In Horses In Yogyakarta Special Region*)
Authors: Yuriadi Yuriadi , Tjahajati Ida , Indarjulianto Soedarmanto , Widiyono Irkham
Published: November 2019

ABSTRACT This research aimed at determining the efficacy of duramectin, oxfendazole, piperazine, and pyrantelpamoate against gastrointestinal worms in horses in Yogyakarta Special Region and Central Java. The object of research involved 40 horses diagnosed with gastrointestinal worm infection. Prior to the research, all of the horses were subjected to examination for clinical symptoms and parasitology laboratory checkup for signs of worm eggs in their feces, and they were pronounced positive for experiment animals with at least 150 eggs per gram of feces per horse. The research horses were weighed to determine the dose of worm medication to be used. The research horses are divided into four treatment groups, each group consists of ten horses. Group I was given duramectin with a dose of 0.2 mg/kg of body weight. Group II was given oxfendazole with a dose of 7.5 mg/kg of body weight, Group III was given 125 mg Piperazin treatment per kilogram of body weight and Group IV was given pyrantelpamoate with a dose of 20 mg/kg of body weight. After receiving themedication, the horses were observed to document the progress in terms of clinical symptoms and the amount and type of worm eggs in their feces every three days for four times in a row. The research data results were tabulated and were descriptive-comparatively analyzed.The research result showed varying efficacy level of worm medication for horses. Oxfendazole kills Strongylus and Parascaris worms. Duramectin kills Strongylus worms and reduce some of the Parascaris worms. Piperazineandpyrantelpamoate kills the Strongylus wormsand reduce some of the Parascaris. Keywords: horses, gastrointestinal worms, Duramectin, Oxfendazole, Piperazine, PyrantelPamoate.
Studi Reseptor Virus Infectious Bursal Disease (IBD) pada Organ Limfoid Ayam Pasca Vaksinasi dengan Metode Imunohistokimia
Authors: Librani Restu , Setiyono Agus , Winarsih Wiwin
Published: November 2019

Infectious bursal disease (IBD) affects economical impact for breeders due to it can cause damage lymphoid organ, especially bursa of Fabricius and causing failure the vaccination program. Infectious bursal disease virus receptors on lymphoid organs suspected contribute to subclinical and clinical IBD incidence in the chickens. The aim of this study was to determine and compare the distribution of IBDvirus receptors on lymphoid organ of the chicken which obtained different IBD vaccination program. The presence of virus receptors in bursa of Fabricius, spleen, and thymus were observed microscopically using immunohistochemical method and evaluated with Image J® software. Monoclonal anti LSCC-BK3 (Gifu University, Japan) antibodies as primary antibody was used in this study. The result showed that IBDvirus receptors found abudantly in the bursa of Fabricius, afterwards in the spleen and thymus. No significant differences of IBD virus receptor distribution within lymphoid organs between chicken which obtained once and twice IBD vaccination. Infectious bursal disease virus receptor distribution in bursa Fabricius chickens aged 23 days received twice IBD vaccination more than once IBD vaccination program.
Isolasi, Identifikasi, dan Serotyping Avibacterium paragallinarum dari Ayam Petelur Komersial yang Menunjukkan Gejala Snot
Authors: Tangkonda Elisabet , Tabbu Charles Rangga , Wahyuni Agnesia Endang Tri Hastuti
Published: November 2019

Infectious coryza (snot) is one of acute respiratory disease in breeders, layers, and broilers caused by Avibacterium paragallinarum (Av. paragallinarum). This disease is very harmful because of its cause decrease in egg production and high morbidity. Snot incident in Indonesia still is reported. Vaccination is one of the best preventive measures, but reports about Av. paragallinarum serotype at the field so lack so that the correspondence between serotype Av. paragallinarum in the field to those used for vaccination is unknown. Av. paragallinarum has strains with different antigenicity and until now known three serotypes there are serotypes A, B and C. Serotypes A and C are pathogenic then serotypes B. The purpose of this study was to isolate, identify and to determine the serotype of Av. paragallinarum from the commercial layer that showing symptoms of snot. Samples were taken from layer which showed symptoms of snot (nasal foul smelling exudate, infra-orbital and wattle swelling, conjunctivitis, and snoring) from some layer farms. Samples were cultured on chocolate agar and then incubated in a candle jar at 37 ᴼC for 18-24 hours. Bacteria colony and cell morphology were observed and performed biochemical tests (catalase, oxidase, urease, indole, and fermentation of carbohydrates) in suspected colonies. Serotypes test was conducted using plate agglutination test (PAT). This study revealed 4 isolates Av. paragallinarum with 2 isolates are serotype B and 2 other are serotype C.
Recombinant Human Erythropoietin: Manfaat dalam Bidang Kedokteran
Authors: Yanuartono Yanuartono , Purnamaningsih Hary , Nururrozi Alfarisa , Indarjulianto Soedarmanto , Raharjo Slamet
Published: November 2019

Recombinant human erythropoietin (rhEPO) is one of the biotechnology-based drugs that are needed by the human medicine and has also been used in the veterinary medicine. Currently RhEPO has been widely used in the world of human medicine for the treatment of anaemia caused by renal failure, cancer, chronic inflammation and AIDS. In veterinary medicine, although there is still not much data on its achievements, rhEPO has also been used for cases of chronic renal failure in dogs and cats. However, since rhEPO is not identical to feline EPO and canine EPO, some patients eventually produce antibodies against the drug. The antibodies not only prevent EPO therapy from being effective, but also may lead to severe and life-threatening anemia. This paper provides a review of the use of RhEPO, rfEPO and rcEPO in veterinary medicine, especially for the purpose of non-regenerative anemia therapy in cases of chronic renal failure in dogs and cats.
Menurunnya Kandungan Kolesterol Telur Itik dengan Pemberian Bawang Putih Segar dengan Waktu Analisis yang Berbeda
Authors: Jaya I Nyoman , Haryani Ni Ketut Dewi , Indarsih Budi
Published: November 2019

The purpose of this research is to know the influence of the giving of fresh garlic against a decrease in cholesterol levels duck eggs with different analysis time. To achieve that goal, then conducted a study using 50 tail as control with local feeding without given garlic and 50 tail given 25 g/head/day of fresh garlic. The data were analyzed using T-Test, the parameters are observed in this research are cholesterol levels, triglyceride egg yolk, the consumption of feed, feed conversion, egg production, egg weight, and mortality. Analysis of cholesterol levels and triglycerides egg yolks are done at the study week I, III, and V with the method extract ether and the procedure CHOD-PAP. The results showed that there is a decrease in cholesterol 152.24 mg per dl (72.19%) and triglycerides of 130.56 mg per dl (23.42%) a very sharp from the first week to the third week. The feed consumption, egg weight, egg production, and feed conversion are not affected by the time of analysis. The results of this study indicate that to get the content of cholesterol and low fat, given fresh garlic for three weeks.  Duck Eggs; Garlic; Cholesterol
Prima Krim sebagai Solusi Penyembuh Luka pada Penderita Diabetes Meli
Authors: Ardhiansyah Rahmad Dwi , Baihaqie Riefky Pradipta , Naufal Muhammad Nuriy Nuha , Nanda Muhamad Atabika Farma , Rahmawati Kurnia , Fibrianto Yuda Heru
Published: November 2019

Number of patients with diabetes mellitus are very large, according to International Diabetes Federation (IDF) in 2013 reaches 382 billion people between the ages of 40-59 years. Diabetic has been characterized as a chronic wounds. The animal blood waste from a slaugther house is still untapped, containing PRP (Platelet Rich Plasma) that can accelerates heal of bone and soft tissue. PRP (Platelet Rich Plasma) was made from the cattle blood waste using centrifugation. The purpose of the study is to prove that the Prima cream can heal the wounds in diabetic patients. Animals used in this study is 20 Wistar rats. Induction of diabetes was using streptozootocin 65 mg/kg and nicotinamide 235 mg/kg. The animal were divided into 4 groups: non-diabetes given placebo (ND-), diabetes given placebo (DM-), diabetic rat given commercial drug were containing chloramphenicol base 20 mg + prednisolone 2.5 mg (DM+), and diabetes given cream PRP at 20% concentration (DM PRP). Parameters used to measure the rate of wound healing is wound size and histopathologic examination. The data were analyzed using Anova One Way at 95% significant rate. PRP DM group had a wound healing faster than ND- group, DM- and DM+. Based on histopathologic examination, such as epitelialization, basal membrane, fibroblasts, collagen tissue, and presence of inflammatory cells, the best curing reaction was showed in DM PRP. PRP 20% cream produces from cow blood waste can accelerate wound healing in diabetes mellitus.
SPECIJALIZACIJA DRŽAVNIH ORGANA U SUZBIJANjU FINANSIJSKOG KRIMINALITETA I KORUPCIJE
Authors: Matić Bošković Marina , Kostić Jelena
Published: November 2019

Tokom 2016. godine, izmenjen je i dopunjen Krivični zakonik. Najviše izmena izvršeno je u pogledu krivičnih dela protiv privrede. S obzirom na to da se ona mogu svrstati u ekonomski (finansijski) kriminalitet, za njihovo otkrivanje i dokazivanje neophodno je posedovanje i nekih dodatnih vankrivičnih znanja. U otkrivanju dela ekonomskog karaktera osim organa formalne socijalne kontrole učestvuju i neke druge institucije. Tako npr. u otkrivanju krivičnih dela na štetu javnih sredstava učestvuje i vrhovna revizorska institucija, a u otkrivanju krivičnog dela pranje novca, nadležne banke ili društva za osiguranje. Dokazi koje ti organi pribave u svom radu od ključnog su značaja za blagovremeno dokazivanje postojanja krivičnog dela i izricanje adekvatne sankcije njihovim izvršiocima. Zbog toga je tokom 2016. godine donet novi Zakon o organizaciji i nadležnosti državnih organa u suzbijanju organizovanog kriminala, terorizma i korupcije. Tim Zakonom su uvedeni novi instituti krivičnog prava: finansijski forenzičari, službenici za vezu i udarne grupe. S obzirom na činjenicu da takve kategorije nisu prepoznate kao subjekti krivičnog postupka u postojećem Zakoniku o krivičnom postupku i da predstavljaju novinu u našem krivičnom zakonodavstvu, primenom dogmatskog i normativno pravnog metoda autorke ukazuju na potrebu unapređenja, zakonske i podzakonske regulative u cilju omogućavanja efikasne primene tih instituta u praksi.
INTERNA KONTROLA RADA POLICIJE U SRBIJI: POLITIČKO-PRAVNI AKSPEKTI
Authors: Leštanin Branko , Nikač Željko
Published: November 2019

Istraživanje polazi od teze da je unutrašnja kontrola rada policije izuzetno značajna zbog kompleksnosti policijskih poslova, koji ponekad pružaju mogućnost povrede ljudskih prava i ograničenje građanskih sloboda. Cilj istraživanja je da se ispita koji su to mehanizmi unutrašnje kontrole, koja je njihova efikasnost u praksi, kao i da se ukaže na internu kontrolu koja treba da obezbedi ograničenje apsolutne vlasti, zakonitost u radu i jednakost građana pred zakonom i daju pojedini predlozi za unapređenje interne kontrole. U radu su metodološki istraženi i analizirani egzaktni pokazatelji primene mehanizama interne kontrole rada policije u Republici Srbiji u sedmogodišnjem periodu (2012–2018). Rezultati istraživanja pokazuju različite trendove u primeni mehanizama interne kontrole u posmatranom periodu. Zaključuje se da su mehanizmi interne kontrole dovoljni ali da ima mesta unapređenju. To se naročito odnosi na potpunu depolitizaciju organizacije i rada policije, pa s tim u vezi i procesa interne kontrole rada policije i njenih pripadnika.
IDEJE JUGOSLOVENSKE RADIKALNE DESNICE U LISTU POLITIČKI GLASNIK
Authors: Dragosavljević Vasilije
Published: November 2019

U radu je data analiza sadržaja lista Politički glasnik sa posebnim osvrtom na tekstove koji govore na temu monarhizma, staleškog državnog uređenja i antisemitizma. Ovaj niz političkih modela, koje su autori članaka preuzimali iz ideološkog korpusa neorojalističkog pokreta Francuska akcija, nadživeće postojanje ovog lista i činiće idejni fundament jugointegralističkih pokreta radikalne desnice (Jugoslovenska akcija i JNP Zbor) tokom 30-tih i 40-tih godina 20. veka. Na osnovu kraćih biografija ključnih članova uredništva i autora koji su sarađivali u listu, pokazana je personalno-organizaciono-idejna veza između kružooka okupljenog oko lista Politički glasnik i političkih pokreta jugointegralističke radikalne desnice.
KRITIČKA ANALIZA DISKURSA I POLITIKA
Authors: Pesic Milena , Stosic Sanja
Published: November 2019

Cilj ovog rada je sagledavanje mogućnosti kritičke analize diskursa da u skladu sa njenim polazištima, analitičkim metodama i teorijskim konceptima ponudi adekvatan tretman političkih problema, odnosno tumačenja političkih diskursa. S tim ciljem najpre smo prikazali glavna shvatanja i koncepte CDA, potom ih prikazali u kontekstu njihovog funkcionisanja spram distinktivnih odlika političkog diskursa.
BEZBEDNOSNI ODGOVOR REPUBLIKE SRBIJE NA UGROŽAVANJE MIGRANTSKOM KRIZOM
Authors: Gligorić Miroslava
Published: November 2019

Predmet rada je bezbednosni odgovor Republike Srbije na njeno ugrožavanje izazvano savremenom migrantskom krizom koja je kulminirala 2015. godine. Bezbednosni izazovi koje sa sobom nosi migrantska kriza, a sa kojima se danas suočava i Srbija, ponajviše su u domenu organizovanog kriminala, odnosno trgovine ljudima i narkoticima, kao i terorističkog i obaveštajnog delovanja.
Cilj rada je da se objasni na koji način je Republika Srbija bezbednosno odgovorila na izazove koje je sa sobom donela migrantska kriza. Namera autora je da utvrdi adekvatnost odgovora Srbije na sve ključne bezbednosne izazove u vezi sa migrantskom krizom, i da predloge kako bi se na osnovu potpunijeg i sistematizovanog saznanja mogla adekvatnije sprovoditi prevencija i uspešnije vršiti suprostavljanje istim.
Metode koje se primenjuju u radu su naučno deskriptivna, analiza sadržaja i statistička metoda.
Rezultat rada je određenje analiziranih aspekata odgovora Republike Srbije na ugrožavanje njene bezbednosti usled migrantske krize u cilju sveobuhvatnijeg sagledavanja validnosti odgovora na opasnosti od migracija, kao i predlozi i preporuke radi još uspešnijeg otklanjanja njihovih negativnih efekata.
Automatización multinivel de celda de manufactura robotizada utilizando máquinas de estados finitos
Authors: Sánchez Chávez Irma Yolanda , Martell Chávez Fernando
Published: November 2019

A practical case of automation of a manufacturing robotic cell is presented, which is solved by finite state machines that implement the operation sequence of every unit of the cell, as well the integration of all the units. In many cases, no methodology is used in automation for the design of control logic and even less for programming. For this reason the finite state machine is shown as a strategy for the design and structured programming applied to programmable logic controllers. Code generation is demonstrated from the proposed finite state machines. Multilevel automation achieves the automated execution of the total functioning of the cell, and also integrates the manual operation mode to allow the direct manipulation of the actuators, as well as a semiautomated operation mode to test or execute the processing of the units individually, and give flexibility before possible interruptions of the cell work cycle. The resultant design satisfies the functional specifications and facilitates the comprehension, maintenance and modification of the automated system. This work contributes with an automation case using methodologic tools, useful for the capacitation in this area, and for the development of competences in the context of industry 4.0.
Mitigación de daños ocasionados por grietas en el suelo
Authors: Auvinet Guichard Gabriel , Sánchez Guzmán Jesús , Pineda Contreras Alma Rosa
Published: November 2019

The design of a trench of granular material is shown. This design can be used to mitigate the damages caused by cracks that have appeared in the soil in certain zones of Mexico City. The most destructive cracks are associated with differential settlements due to the regional subsidence of Mexico City and can show escarpments of considerable height. The proposal solution consists of constructing a trench of sand on the crack line, called “Dissipative box of unit deformations”. The trench behavior is assessed by means of numerical simulations with discontinuous media approach using the discrete element method. It is drawn that the unit deformations (differential settlements/horizontal distances) on the surface decrease when the depth of trench increases. The simulations allow to obtain an optimal design of the dissipative box distributing the vertical displacements in a sufficient horizontal length so that the escarpment disappears and is replaced by a surface with moderate inclination. In this way, a road affected by a crack can continue open to traffic. Analyzes with continuous media approach are presented, their results are compared with the discrete approach ones. Some conclusions and practical recommendations for the mitigation of damage caused by cracks are given.
Determination of fracture toughness and elastic module in materials based silicon nitride
Authors: Carrasquero Rodriguez Edwuin Jesus , Minchala Marquino Jaime Moises , Romero Romero Byron Ramiro , Lopez Lopez Luis Marcelo , Fajardo Seminario Jorge Isaac
Published: November 2019

The knowledge of the mechanical properties of any material subjected to loads is necessary for its use in structural applications. Silicon nitride (Si3N4) ceramics are well-known materials used in engineering applications due to their outstanding combination of high strength and fracture toughness. The most studied mechanical properties of Si3N4 are hardness, fracture toughness and mechanical resistance. Recent advances in the production processes that incorporate high purity rare earth elements as sintering additives have improved these mechanical properties. Using Vickers indentation method, the elastic module and fracture toughness of Si3N4 based materials modified with La2O3, Y2O3 and Al2O3 were determined as a function of the cracking system type that prevails under the effect of load. The results indicate that adding rare earth to the matrix increased the fracture toughness the Si3N4 base ceramic Samples containing La2O3+Y2O3 showed higher values of fracture toughness than the ones with Al2O3+La2O3, regardless of the equation used in the calculations. Meanwhile the elastic module decrease approximately 100 GPa for both types of nitrides by the effect of the temperature.
STAN PASAR SEBAGAI JAMINAN BERDASARKAN PERJANJIAN TENTANG PEMBERIAN HAK MEMAKAI RUANG (STAN) DI BANK CENTRAL ASIA
Authors: Rianti Novia
Published: November 2019

Space rights agreement is a part of lease agreement. Leasing is an agreement that gives a right called individual rights. It is because the right to lease arises from an agreement between one legal subject to another. Thus, this right can only be accountable to the opponent of the contract in accordance with the principle of privity of contrac. A lease agreement aims at providing the right only to use the property, and not to own it. Therefore, lease agreement only gives individual rights, not property rights. On the other hand, as we know, fiduciary provides object guarantees, which is included in constitutum possessorium (the object transferred remains within the control of the fiduciary giver). The air rights, the market stall, from the agreements of rights granting, are clearly included in individual rights, rather than property, which should not be imposed on fiduciary guarantees. This research is conducted by applying doctrinal research. It adapts statute approach, conceptual approach, and case study for its methodological problem approach. This study analyzes the market stall usage rights as an object from the perspective of security laws and Fiduciary on the usage rights upon a market stall by banks. The results of the research showed that by reviewing it further using air rights perspective, the air rights upon a market stall were included in lease rights. The right to use the stall is not property rights, but is an individual right. It is based on the law of lease rights. In addition, the debtor, as the tenant, only controls the leased objects to make use of it, not for the purpose of owning it. In that way, the lease itself does not result in property rights. However, if it is reviewed further based on the air rights, this can be categorized as an object with security laws, because the air rights fulfill the requirements as an object that can be guaranteed. It is because it has economic value and can be transferred, even though it is approved by another party. Since the air rights are individual right, it cannot be used as a guarantee for pawn, mortgage, and Fiduciary.
PERTANGGUNGJAWABAN PIDANA MEDIA OT ATAS PEMBERITAAN TIDAK BENAR BERDASARKAN UNDANG-UNDANG NOMOR 40 TAHUN 1999 TENTANG PERS
Authors: Maulana Katon Fajar , Setyaningrum Ami
Published: November 2019

The purpose of this paper is to deeply understand criminal offense committed by the press for having announces that chief editor of the private television has caught by KPK hand fishing operation with the aim of making bombastic news, of course, the mass media in this case OT media will have a huge advantage over the news. The results showed that OT media in informing the US was caught in the KPK hand fishing Operation (KPK HFO) be accountable for their crime by the Press Law because; Based on the news that is not true, which stating that the US was caught KPK, the online media has violated Article 5 (1) of the Press Law, which determines that the national press is obliged to proclaim the events and opinions with respect religious norms and a sense of decency community as well as the presumption of innocence. In this case the media OT violates the presumption of innocence; Media OT does not carry out the role of the press as set forth in the provisions of Press law Article 6 letter C, which develop public opinion based on information that is precise, accurate, and true. Coverage improper done by media OT impressed incite people to cause controversy among the public; to determine Corporate criminal liability of the OT media is by using the theory of criminal liability Vicarious Liability, because the subject is corporate crime after the devolution of criminal liability of its officers, in this case the editor in chief in accordance with the explanation of Article 12 in conjunction with Article 18 of the Press Law. Based on the Fault made by the OT media, the online media can be penalized as provided for in Article 18 of the Press Law, which is subject to a maximum fine of Rp. 500,000,000.00.
PENEGAKAN HUKUM ATAS KETIDAKPATUHAN PERUSAHAAN DALAM MENERAPKAN SISTEM MANAJEMEN KESELAMATAN DAN KESEHATAN KERJA
Authors: Akbar Fadli , Santoso Budi , Hamidah Siti
Published: November 2019

PT. Karebet Mas Indonesia Branch of Muara Jawa has mentioned the existence of facilities for personal protective equipment against workers/laborers, but in the implementation of PT. Karebet Mas Indonesia does not all carry out the contents of the agreement and only partially runs for approximately 2 years. The formulation of the problem taken in this reserch is what the obstacles faced by the Manpower and Transmigration Agency of East Kalimantan Province are in enforcing sanctions for companies that do not comply with the occupational health and safety management system. This type of research is empirical juridical with a sociological juridical research approach. The conclusion of this research is the obstacle of the Manpower and Transmigration Office in enforcing the law because the human resources and budgetary funds that do not support and in finding violations of the law on the Manpower and Transmigration Office of East Kalimantan Province are passive.
PERLINDUNGAN HUKUM ATAS DATA PRIBADI BAGI KONSUMEN DALAM KLAUSULA EKSONERASI TRANSPORTASI ONLINE
Authors: Rizal Muhammad Saiful , Yuliati Yuliati , Hamidah Siti
Published: November 2019

The exoneration clause is still used in the online transportation agreement clause, when the user registers. This has an impact on the legal uncertainty for consumers in the protection of their personal data managed by the application business actors. This study aims to analyze the presence or absence of violations in Article 18 of the Consumer Protection Law related to exoneration clauses in online transportation, and forms of legal protection of consumer personal data in standard contracts. This research is a normative legal research, with a statue approach and comparative approach. The results of this study are that application business actors have transferred the responsibility of protecting consumer personal data which should be the obligation of the application business actor. The application of exoneration clauses carried out by application businesses is very detrimental to consumers by feeling insecure and comfortable in using online transportation services. Forms of legal protection from the government related to consumer personal data in using online transportation services with the obligation of businesses to revise and replace losses suffered by consumers.
The antioxidant effect of beta-alanine or carnosine supplementation on exercise- induced oxidative stress: a systematic review and meta-analysis
Authors: França Elias , Santos Lira Fábio , Ruaro Marcio Flávio , Hirota Vinicius Barroso , Waziry Paula Faria , Miranda Maria Luiza de Jesus , Nicoletti Maria Aparecida , Fukushima André Rinaldi , Caperuto Erico Chagas
Published: November 2019

O objetivo deste estudo foi realizar uma revisão sistemática e meta-análise dos artigos que abordaram o efeito da suplementação de BA ou carnosina sobre o estresse oxidativo (TE) induzido pelo exercício físico (EF). Antes de maio de 2018, pesquisamos em todo PubMed, CAPES Periodic e SPORTDiscus modelo humano de revisão por pares, estudos randomizados de controle com suplementação crônica de BA ou carnosina em SO induzida por PE. Um total de 128 citações foram encontradas. Apenas quatro artigos preencheram critérios para inclusão. Todos os quatro estudos utilizaram jovens saudáveis, sedentários, recreativos ou atléticos. Após uma suplementação crônica com BA ou carnosina, os estudos avaliaram a SG induzida por PE imediatamente e várias horas após o exercício (0,5 a 48 h). Em resposta ao SO induzido por PE, quando comparado ao placebo, a suplementação com BA / carnosina aumentou a capacidade antioxidante total [TAC; Tamanho do Efeito (ES) = 0,35, Intervalo de Confiança 95% (CI) 0,06 a 0,65, p = 0,02] e concentrações de glutationa (GSH; ES = 0,75, IC 95% 0,32 a 1,19, p = 0,0007) enquanto diminuiu os marcadores OS diretos ( ES = -1,19, IC 95% -1,48 a -0,80, p
O ESTÁGIO SUPERVISIONADO EM SERVIÇO SOCIAL
Authors: Lewgoy Alzira Maria Baptista
Published: November 2019

Este artigo é produto da exposição do Módulo VI “O Estágio Supervisionado em Serviço Social”, do Curso de Atualização “As Diretrizes Curriculares e o Projeto de Formação Profissional de Serviço Social (Abepss Itinerante)”. Apresenta-se como elementos introdutórios as ideias construtoras do planejamento coletivo deste módulo, cujo produto resultou na elaboração de um programa constituído de ementa, objetivos e conteúdo programático. Nele, contextualiza--se a conjuntura sócio-histórica e política da formação em Serviço Social e as tensões presentes na relação entre formação e mercado de trabalho. Além disso, são abordados os instrumentos normativos do estágio supervisionado, fruto de trabalho coletivo e de acúmulo político profissional do Serviço Social brasileiro, apontando sua direção teórica, ética e política. Neste percurso, apresenta-se o debate sobre o estágio supervisionado no que se refere aos desafios e às estratégias para a articulação entre formação e exercício profissional. Conclui-se, portanto, que o produto deste módulo situa-se no campo dos estudos sobre o estágio supervisionado, afinado no horizonte social e ético-político do projeto profissional no sentido de socialização e de apropriação coletiva de um saber que, alicerçado nas dimensões da competência profissional (ético-política, teórico-metodológica e técnico-operativa) faça sentido, diferença e consequência no cotidiano da formação e do exercício profissional. Palavras-Chave: Formação Profissional, Estágio Supervisionado, Serviço Social.
Orígenes, formación y testamento del escultor renacentista Arnaut Spierinck, o Arnao de Bruselas
Authors: BARRÓN GARCÍA Aurelio Á.
Published: November 2019

El testamento de Arnao de Bruselas permite saber que se llamaba Arnaut Spierinck. Su hermano Gil Spierinck posiblemente se corresponda con el escultor y pintor activo en Aldenarda de 1523 a 1536, año en el que Arnao aparece en Zaragoza al ingresar en el taller de Damián Forment. Se aportan también algunos datos sobre el retablo mayor de Santa María de Palacio en Logroño, obra maestra de Arnao, y de otros retablos en los que intervino el escultor: Nalda –junto con Andrés de Araoz–, Torrecilla sobre Alesanco, Aldeanueva de Ebro y Tómalos en Torrecilla de Cameros, contratado por el pintor Juan de Rojas.