bluuebunny/crossref_metadata_2025 huggingface dataset:
Políticas alimentarias locales en Argentina: un caso de estudio
Authors: Ramos Gimena , Elorza María Eugenia , Pérez Stella Maris
Published: May 2021

Objetivo: evaluar un programa de entrega de módulos alimentarios implementado en la ciudad de Bahía Blanca (Bs. As.), durante el primer semestre de 2018. Metodología: a partir de datos provistos por la Oficina de Estadísticas Sociales del Municipio, se describió el programa y se caracterizó a la población beneficiaria durante el primer semestre del año 2018. Se analizó la evolución mensual de la cantidad de módulos entregados y de beneficiarios en relación a la variación de precios y se evaluó la cobertura del programa en relación a la necesidad alimentaria medida a partir de la población bajo la línea de indigencia. Resultados: la población demandante de módulos alimentarios posee características que coinciden con las de los hogares urbanos con inseguridad alimentaria en Argentina. Se comprobó que la demanda se comporta de acuerdo con las condiciones económicas del momento y que constituye sólo una proporción de la totalidad de individuos en situación de indigencia en la ciudad. Limitaciones: no se midió la inseguridad alimentaria de la población bajo estudio. Los resultados vinculados al alcance del programa se estimaron con base en escenarios según los parámetros estimados en una muestra mientras que la focalización también se evaluó a partir de una muestra de la población bajo programa. Conclusiones: la asistencia directa mediante la entrega de módulos alimentarios implica un retroceso en las políticas alimentarias y sociales, en el sentido de limitar la autonomía y toma de decisiones por parte de los beneficiarios. Si bien se ha avanzado hacia nuevas modalidades de asistencia mediante transferencias monetarias, la entrega de alimentos constituye una política que continúa realizándose, especialmente en momentos de crisis socioeconómicas o sanitarias.
Differential Impairments in Incentive Learning Caused by First‐ and Second‐ Generation Antipsychotic Drugs
Authors: Florczynski Matthew
Published: May 2021

Schizophrenia is a neuropsychiatric disorder characterized by increased function of dopamine in the brain.  Dopamine release is a natural response to reward.  It promotes incentive learning (IL), a process by which neutral stimuli acquire the ability to elicit approach and other responses.  A recent model characterizes dopamine‐mediated IL as a progressive process with early and late stages accompanied by a shift in neural control from the nucleus accumbens (NAc) to the dorsolateral striatum (DLS).  A parallel can be drawn to differences in regionally specific neural responses generated by first‐ and second‐generation antipsychotic drugs (APDs) used to treat schizophrenia.  APDs are dopamine receptor antagonists, but first‐generation APDs affect the NAc and DLS while second‐generation APDs affect primarily the NAc.  We compared the effects of APDs on IL. Rats (N = 48) were trained to press a lever forfood pellets in an operant chamber.  Intraperitoneal injections (1 hr before testing) of the first‐generation APD haloperidol (0,0.05,0.10,0.20 mg/kg) or of the second‐generation APD risperidone (0,0.20,0.40,0.80 mg/kg) induced dose‐dependent suppression of lever pressing on days 1‐4, with the highest dose groups failing to demonstrate any evidence of previous learning on day 5 when tested drug‐free.  On days 16‐20 haloperidol induced a day‐to‐day suppression not seen with risperidone.  The results suggest that the effects of first‐ and second‐generation APDs on learning processes putatively mediated by the NAc and DLS can be differentiated experimentally.  The findings imply that APDs may differentially affect IL inpatients with schizophrenia.
Ancient Atmospheric Lead Pollution
Authors: Varaschin Julian
Published: May 2021

In the early 90s, evidence was found in ice cores taken from Greenland of increased levels of ancient atmospheric lead, preserved by way of the annual precipitation that eventually formed into ice sheets. Since that time, similar records of atmospheric lead pollution have been uncovered in myriad other naturally forming deposits, including lake sediments and bogs. These records of lead pollution are presumed to reflect an increase in anthropogenic atmospheric lead pollution as metal became more heavily utilized by ancient peoples. This pollution confirmed for many the size and sophistication of the Roman economy. The records exhibit a clear peak around the beginning of the first millennium, roughly the midpoint of the Roman Empire and such levels were not seen again until after the industrial revolution was well underway. This peak in atmospheric lead is thought to show the climax of Roman Industry, followed by a subsequent decline and historians and scientists have sought to use this evidence as a proxy for the ancient world economy, but more specifically for the so called rise and fall of the Roman Empire. This presentation will explore the science behind linking the atmospheric lead pollution to Roman mining activities and why lead pollution is so strongly thought to reflect the roman economy. Alternative theories as to how atmospheric lead was produced in such quantities will be explored, including, increased agriculture and wood burning. Lastly, confounding factors will be considered such as volcanism and other ancient sources, including mining in Asia Minor and Han China.
Reverse Butterfly Effect: Saving Alternate Histories of Virtual Worlds
Authors: Ye Zi
Published: May 2021

Chaos theory is a recent field of study which has become extremely influential in science and in popular culture. Chaos theory deals with complex, non‐linear systems which are extremely sensitive to their initial conditions (commonly known as the butterfly effect), and whose behaviour quickly become unpredictable over short periods of time. Despite their seemingly random nature, chaotic systems are fully deterministic. This means that the same initial conditions will always yield the same future states. When I looked at the butterfly effect backwards, and applied it to computer simulations, the result was a way to store many alternate histories of virtual worlds in a very small amount of data. This time storage model may have applications in scientific simulation, gaming, and cryptography, and provides a different look at chaos theory.
What are the Chances...?
Authors: Moon Nathalie
Published: May 2021

We deal with ‘probabilities’ every day of our lives. Often, we weigh our chances instinctively, based on intuition or past experience. But how well does this really serve us? The math behind probability theory can be brought to bear on countless real‐life situations in many fields, including clinical trials, weather forecasting, insurance policies, and scientific experiments. By studying a simple probability paradox, we will highlight the discrepancy between intuition and reality. What are your chances of learning something in this session? One hundred percent!
3. Quantifying Sediment Deposition Patterns of Lake Underflows Using a Novel Underflow Sediment Trap
Authors: Bassutti Anthony
Published: May 2021

Lake underflow deposition is an important limnological process which greatly affects sediment deposition patterns and lake varve formation. Currently no feasible, cost‐effective device or method has been regularly utilized to quantify sediment deposition patterns. This study utilizes a novel underflow trap which was deployed at two locations at the bottom of a High Arctic lake subject to seasonal river inflow. It was found that a peak in lake bottom temperature departures, lake bottom turbidity, and river suspended sediment concentration are strongly associated with peak underflow deposition events. Furthermore, evidence shows that deposition amounts are greatly reduced as underflow distance increases. One year was also found to show a clear lag in deposition patterns between two distant stations. This method of quantifying underflow deposition is useful for determining deposition patterns over time and space. This knowledge is useful in monitoring the changes in the lake bottom waters, and for aiding in the reconstruction of past sediment deposition patterns.
Representasi Makna Lirik Lagu Lekas Pulih bagi Pasien Covid-19
Authors: Hendra Hendra , Wahid Umaimah
Published: May 2021

Artikel ini berisi Analisis Semiotika lirik lagu “Lekas Pulih” Karya Fiersa Besari. Metode semiotika yang akan digunakan adalah semiotika Saussure. Dalam teori Saussure dijelaskan bahwa tanda memiliki unsur yang saling berhubungan yaitu penanda (signifier), petanda (signified). Proses ini menghubungkan antara lirik lagu dengan dunia eksternal yang sesungguhnya. Hasil penelitian ini, lirik lagu “Lekas Pulih” memiliki makna yang saling berkaitan dan mengandung pesan motivasi yang sangat kuat, karena di dalamnya terdapat banyak kata-kata yang sifatnya sangat membangun dalam memberikan motivasi kepada pasien yang terpapar Covid 19, serta meyakinkan mereka untuk sembuh dan berharap situasi akan kembali pulih. Lirik itu memotivasi para tenaga medis, dan pasien yang terkonfirmasi covid 19, jangan pernah berhenti untuk berjuang dalam keadaan yang sangat sulit tapi bisa memotivasi dan menguatkan satu sama lain. Model teori dari Saussure lebih memfokuskan perhatian langsung kepada tanda itu sendiri. Dalam penelitian terhadap lirik lagu "Lekas Pulih" ini, peneliti membuat interprestasi dengan membagi keseluruhan lirik lagu menjadi beberapa bait dan selanjutnya perbait akan dianalisis dengan menggunakan teori semiotika dari Saussure.
Pengaruh Sumber Informasi dan Dukungan Kelembagaan terhadap Kemandirian Petani di Provinsi Sumatera Selatan
Authors: Kusumadinata Ali Alamsyah , Sumardjo Sumardjo , Sadono Dwi , Burhanuddin Burhanuddin
Published: May 2021

The weak independence of farmers in managing farming is characterized by weak levels of farmer production and selling prices that are still determined by market conditions. The information sources owned by farmers are not strong enough to help farmers in analyzing problems faced by farmers ranging from land preparation, cultivation, harvesting to post-harvest. Therefore, the study aimed to look at the influence of agricultural information sources on the support of the institutional environment of farmers on the independence of farmers. This research used a quantitative approach with survey methods in Ogan Ilir Districts and Banyuasin Districts, South Sumatera Province. This study used a sample of 294 farmers who joined farmer groups. This research showed that the weak source of information used by farmers and the low support of the institutional environment results in the farmers' independence being quite weak. Farmers have not been able to build competitiveness, filter and partnership in the scope of their lives up to farmer groups. The independent model of farmers was able to explain 91% of sources of information and institutional environment support. Therefore, it was necessary to strengthen accurate, correct, in-depth information and adapt it to local site conditions.
Environmentally Friendly Rice Farmer Empowerment for Sustainable Food Security in Banten Province
Authors: Mulyaningsih Asih , Suherna Suherna , Gunawan Gugun
Published: May 2021

Empowerment is a key factor in accentuating the role of farmer communities as the main actors in managing the cultivation of Indonesian staple food, that is, rice. This study was intended to analyze the factors influencing the empowerment of farmers to manage environmentally friendly lowland rice production for sustainable agricultural development in Banten Province. With a descriptive design, this research collected data through a questionnaire survey involving 180 respondents, sampled from a predefined population of rice farmers. It was carried out in three regencies in the province, namely Serang, Pandeglang, and Lebak, for three months from April to June 2019. The data were analyzed using statistical inference, SEM, in LISREL 8.73 (Linear Structural Relationships). The results showed that the empowerment of lowland rice farmers to adopt eco-friendly innovation was determined by individual characteristics (i.e., non-formal and formal educational attainment and cosmopolitanism) and the existence of encouragement to implement the innovation (i.e., support from farmer community, market support, and technological information support). In conclusion, to increase the empowerment of rice farmers in the scheme of sustainable food security, farmers, government, and other relevant parties need to pay attention to the characteristics of innovation users and promote the adoption of eco-friendly practices in lowland rice cultivation.
IMAGINÁRIOS DE SALVADOR SOB AS LENTES DA PANDEMIA
Authors: Franco Maiara Bomfim , Jesus Liliane Vasconcelos de
Published: May 2021

Perceber a cidade de Salvador pelas lentes desfocadas de uma crise sanitária sugere releituras e ressignificação sobre como essa cidade tem se revelado, à medida que o distanciamento é evocado como a principal medida protetiva contra o recente perigo invisível. Desse modo, o presente artigo propõe dialogar com narrativas que percorrem o imaginário simbólico da cidade por meio das tendências geradas pela era pandêmica, a fim de investigar os modos como novos olhares têm sido estabelecidos sobre a capital baiana. Nesse aspecto, serão analisadas as crônicas da escritora Lorena Grisi (2020) e o vídeo Uma Saudade Chamada Salvador (2020) protagonizado pela artista Larissa Luz. Os métodos utilizados buscarão identificar representações da cidade de Salvador a partir de uma perspectiva multidisciplinar, analisando o imaginário da cidade por meio de imagens e representações presentes no levantamento bibliográfico. Com isso, percebeu-se que a cidade de Salvador tem fomentado mediações introspectivas e saudosas, as festas silenciadas, os encontros adiados, projeções atravessadas pelas imagens de um futuro incerto em brevidades esperadas.
A MÍDIA NA FORMAÇÃO DA AGENDA NAS POLÍTICAS PÚBLICAS DE SAÚDE NA PANDEMIA DA COVID-19
Authors: Borges Marcia Leite , Menezes Vinícius , Patella Ana Paula Dupuy , Moura Danieli Veleda , Santos Carícia Hercilia Oliveira dos , Nogueira Racquel Nagem Daier
Published: May 2021

O presente estudo analisa a influência da mídia no processo decisório que resulta na formação da agenda das políticas públicas voltadas à área de saúde. A problematização do tema “formação de agenda” norteará o referencial teórico e metodológico a fim de abordar as questões pertinentes ao campo das políticas públicas de saúde no contexto brasileiro no período de pandemia da COVID-19. O problema de pesquisa visa a apurar como se configuram as escolhas acerca da formação de agendas em políticas públicas na área da saúde?  A hipótese afirma que a mídia exerce um papel central na escolha das prioridades sociais através do discurso dirigido aos grupos de interesse.
Caracterização dos profissionais da linha de frente em um hospital de referência durante a pandemia pelo COVID-19
Authors: Sousa Josué Rodrigues de , Conceição Edna Cristina Vieira , Marsola Lourival Rodrigues , Maia Naiara Chaves , Oliveira Gloria Yanne Martins de , Barreto Juliana Li Ting Matos Sun , Queiroz Perla Suely Gaia Raniéri , Costa Deyse Cristine dos Santos , Sena Emily Manuelli Mendonça , Reis Danielle Saraiva Tuma dos
Published: May 2021

Objetivo: Conhecer como se apresentou a infecção humana pelo SARS-CoV-2 em profissionais da linha de frente de um hospital público durante a pandemia pelo COVID-19. Métodos: Estudo quantitativo, transversal com participação de profissionais das áreas assistenciais em um hospital de referência no atendimento à COVID-19. Resultados: Dos 198 profissionais que participaram, maioria era do sexo feminino entre 30 a 39 anos. Entre as categorias tiveram técnicos de enfermagem (26,8%), enfermeiros (20,7%) e médicos (13,1%). Todos receberam algum equipamento de proteção individual (EPI), contudo 20,7% não promovia proteção necessária. 72,2% recebeu treinamento sobre medidas de proteção, mas 67,7% relatou ser insuficiente. 71,1% dos profissionais foram sintomáticos para COVID-19, com relato de cefaléia, mialgia e febre. Os testes realizados apresentaram positividade para TR (67%), RT-PCR (72,7%) e Sorológicos (78,6%). O tratamento adotado pelos sintomáticos foi antitérmicos e analgésicos (61,3%), antibioticoterapia (59,2%), corticoides (26,1%), Ivermectina (21,1%) e Cloroquina ou hidroxicloroquina (15,5%). Conclusão: A pandemia pelo COVID-19 impõe grandes prejuízos aos serviços de saúde, com exposição dos profissionais ao adoecimento e a falta de oferta do equipamento de proteção individual.
Tecnologias educacionais desenvolvidas para o cuidado ao paciente diabético: revisão integrativa da literatura
Authors: Souza José Vinícius de , Ferreira Mateus Andrade , Andrade José Isaac Alves de , Calixto Anna Valéria Duarte , Lira Rafaelle Cavalcante de
Published: May 2021

Objetivo: Realizar um levantamento bibliográfico sobre as principais tecnologias educacionais utilizadas no cuidado com pacientes com Diabetes Mellitus. Métodos: Trata-se de uma revisão integrativa de literatura retrospectiva com caráter descritivo-exploratório realizada nas bases de dados LILACS, Web of Science, PUBMED e SCIELO, por meio do cruzamento dos descritores “Diabetes Mellitus”, “Complicações do Diabetes”, “Tecnologia Educacional”, “Estudo de Validação” e “Jogos e Brinquedos”, nos idiomas português, inglês e espanhol. Resultados: A amostra final foi constituída de 20 artigos que emergiram duas categorias temáticas: Tipos de tecnologias cuidativo-educacionais utilizadas na promoção do autocuidado em diabéticos e Interface entre aprendizagem significativa e as dificuldades na implementação das tecnologias cuidativo-educacionais. O cenário atual de produção de educação em saúde utiliza, sobretudo, como recurso, as mídias digitais como games, porém ainda conta com a participação significativa de ferramentas impressas e físicas. É notória a necessidade de adaptação quanto ao conteúdo e linguagem a fim de atender à demanda sociocultural do público abordado. Considerações Finais: A produção de tecnologias educacionais para diabéticos está, em sua maioria, pautada em mídias digitais. Notou-se a carência de jogos de tabuleiro para o público em questão.
Aspectos epidemiológicos da hepatite B no município de Teresina
Authors: Evangelista Camila Brígida de Abreu , Carvalho Gabriela Dantas , Silva Kamila Cristiane de Oliveira , Oliveira Tiago da Rocha , Neta Neusa Barros Dantas , Rodrigues Augusto César Evelin , Rocha Valéria Alves da , Silva Marcélia Gomes , Lima Érica Melo , Carvalho Rayssa Maria de Araujo
Published: May 2021

Objetivo: Traçar o perfil epidemiológico da infecção por hepatite B na cidade de Teresina-PI. Métodos: Trata-se de um estudo documental, quantitativo e descritivo, realizado no período de junho a outubro de 2020, através dos casos de hepatite B notificados no banco de dados do SINAN, na versão SINAN NET, disponibilizados pelo Departamento de Informática do Sistema Único de Saúde (DATASUS), no período de 2014 a 2018. Os dados foram organizados em planilha digital Microsoft Office Excel 2019 e apresentados em tabelas, ordenadas por caracteres quantitativos, adotando como critério de distribuição a amostra e porcentagem, com o auxílio dos programas computacionais TabWin versão 4.1.5. Resultados: Foram contabilizados 32 casos, com maior incidência para os anos de 2014 e 2017, ambos reagentes para o marcador sorológico HBsAg, tendo predomínio para o gênero feminino, idade entre 20 e 39 anos e manifestado na forma crônica, sendo a atividade sexual a principal via de transmissão. Conclusão: Teresina tem alta endemicidade, com prevalência para a idade, meio de contaminação e diagnóstico clínico manifestado.
Reducing Risk of Stroke When You Have Atrial Fibrillation - Evidence Update for Patients
Authors:   Patient-Centered Outcomes Research Institute (PCORI)
Published: May 2021

People with atrial fibrillation (AFib) or atrial flutter are five times more likely to experience a stroke compared with people who have a normal heart rhythm. The risk of stroke increases with age. Medicines that keep the blood from clotting, called anticoagulants, lower the risk of stroke but can also cause serious bleeding.
Teaching Tools to Teach Geriatric Medicine to Family Medicine Residents
Authors:   Department of Family Medicine, Loma Linda University Health, Loma Linda, USA, EE Jaqua , V Nguyen ,   Department of Family Medicine, Loma Linda University Health, Loma Linda, USA, A Jubran ,   Department of Family Medicine, Loma Linda University Health, Loma Linda, USA, S Park ,   Department of Family Medicine, Loma Linda University Health, Loma Linda, USA, A Wijatyk ,   Department of Family Medicine, Loma Linda University Health, Loma Linda, USA
Published: May 2021

Objective: To determine if pocket-sized, reference guides are helpful tools for teaching geriatric medicine to family medicine residents. Setting: Loma Linda University Healthcare Education Consortium, a family medicine residency in San Bernardino County, California. Participants: Family medicine residents that successfully completed the required geriatrics rotation between July 2019 and June 2020. Results: From the twelve family medicine residents, 100% believed their geriatric medicine rotation helped them to be successful in residency. The preferred study tool was the pocket guides, mainly the “Geriatric Medicine Pocket Guide” and “2019 AGS Beers Criteria”. For a more comprehensive reading, the study tool most used was search engines such as Up-to-date and Dynamed. Geriatrics at Your Fingertips (Reuben et al., 2016) and the “Guiding Principles for the Care of Older Adults with Multimorbidity Pocket Card” were not as helpful due to the perceived increased efforts to rapidly find clinically relevant information. Conclusion: Pocket guides, especially “Geriatric Medicine Pocket Guide” and “2019 AGS Beers Criteria”, are helpful teaching tools that can be used to augment geriatric medicine education in a family medicine residency.
Automated Mechanism Generation Using Linear Scaling Relationships and Sensitivity Analyses Applied to Catalytic Partial Oxidation of Methane
Authors: Mazeau Emily , Satpute Priyanka , Blondal Katrin , Goldsmith Franklin , West Richard
Published: May 2021

Kinetic parameters for surface reactions can be predicted using a combination of DFT calculations, scaling relations, and machine learning algorithms; however, construction of microkinetic models still requires a knowledge of all the possible, or at least reasonable, reaction pathways. The recently developed Reaction Mechanism Generator (RMG) for heterogeneous catalysis, now included in RMG version 3.0, is built upon well-established, open-source software that can provide detailed reaction mechanisms from user-supplied initial conditions without making a priori assumptions. RMG is now able to estimate adsorbate thermochemistry and construct detailed microkinetic models on a range of hypothetical metal surfaces using linear scaling relationships. These relationships are a simple, computationally efficient way to estimate adsorption energies by scaling the energy of a calculated surface species on one metal to any other metal. By conducting simulations with sensitivity analyses, users can not only determine the rate limiting step on each surface by plotting a "volcano surface" for the degree of rate control of each reaction as a function of elemental binding energies, but also screen novel catalysts for desirable properties. We investigated the catalytic partial oxidation of methane to demonstrate the utility of this new tool and determined that an inlet gas C/O ratio of 0.8 on a catalyst with carbon and oxygen binding energies of -6.75 eV and -5.0 eV, respectively, yields the highest amount of synthesis gas. Sensitivity analyses show that while the dissociative adsorption of O2 has the highest degree of rate control, the interactions between individual reactions and reactor conditions are complex, which result in a dynamic rate-limiting step across differing metals.
Total Synthesis of (+)-Spiroindimicin A via Asymmetric Palladium-Catalyzed Spirocyclization
Authors: Zhang Zhen , Ray Sneha , Imlay Leah , Callaghan Lauren , Niederstrasser Hanspeter , Mallipeddi Prema Latha , Posner Bruce A. , Wetzel Dawn , Phillips Margaret , Smith Myles
Published: May 2021

The spiroindimicins are a unique class of chlorinated indole alkaloids characterized by three heteroaromatic rings structured around a congested spirocyclic stereocenter. Here, we report the first total synthesis of (+)-spiroindimicin A, which bears a challenging C-3’/C-5’’-linked spiroindolenine. We detail our initial efforts to effect a biomimetic oxidative spirocyclization from its proposed natural precursor, lynamicin D, and describe how these studies shaped our final abiotic 9-step solution to this complex alkaloid built around a key asymmetric Pd-catalyzed spirocyclization. Scalable access to spiroindimicins A, H, and their congeners has enabled discovery of their activity against several parasites relevant to human health, providing potential starting points for new therapeutics for the neglected tropical diseases leishmaniasis and African sleeping sickness.
Quantum Interference and Spin Filtering Effects in Photo-responsive Endoperoxide Based Single Molecular Device
Authors: Bajaj Ashima , Khurana Rishu , Ali Md. Ehesan
Published: May 2021

The development of stimuli responsive systems that can switch between two distinct spin states under the application of an external stimuli has always remained an illusory challenge. Here, we report a stimuli-based spin filter by utilizing photo-responsive endoperoxide (EPO) based single molecule device. The photo-irradiation on EPO triggers the homolytic cleavage of the peroxide O-O bond generating diradical intermediate centered on two O-atoms which facilitates high spin filtering efficiency when placed between gold electrodes. The broken conjugated scenario due to peroxide bridge of EPO hinders the propagation of de-Broglie waves across the molecular skeleton. While the diradical intermediate of EPO yields high conductance for one of the spin configuration. The transmission characteristics of various photoproducts along the photochemical reaction pathway of EPO are also investigated using density functional theory in combination with non-equilibrium Green’s function (NEGF-DFT) technique. We demonstrate the key role played by Quantum Interference (QI) effects in dramatic modulation of conductance arising due to different degree of conjugation along the reaction pathway of EPO.
Vinyl-fluorene Molecular Wires for Voltage Imaging with Enhanced Sensitivity and Reduced Phototoxicity
Authors: Boggess Steven , Gandhi Shivaani , Miller Evan
Published: May 2021

Fluorescent voltage indicators are an attractive alternative for studying the electrical activity of excitable cells; however, the development of indicators that are both highly sensitive and low in toxicity over long-term experiments remains a challenge. Previously, we reported a fluorene-based voltage-sensitive fluorophore that exhibits much lower phototoxicity than previous voltage indicators in cardiomyocyte monolayers, but suffers from low sensitivity to membrane potential changes. Here, we report that the addition of a single vinyl spacer in the fluorene molecular wire scaffold improves the voltage sensitivity 1.5- to 3.5-fold over fluorene-based voltage probes. Furthermore, we demonstrate the improved ability of the new vinyl-fluorene VoltageFluors (v-fVFs) to monitor action potential kinetics in both mammalian neurons and human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Addition of the vinyl spacer between the aniline donor and fluorene monomer results in indicators that are significantly less phototoxic in cardiomyocyte monolayers. These results demonstrate how structural modification to the voltage sensing domain have a large effect on improving the overall properties of molecular wire-based voltage indicators.
Assessment of Perception, Knowledge and Practice of Healthcare Professionals Regarding Pharmaceutical Advertisement (PA) in Pakistan
Authors: Muhammad Abdul Quddoose  , Azhar Hussain  , Madeeha Malik  , Nabeel Siddique
Published: May 2021

Pharmaceutical advertising (PA) effects both healthcare professionals and consumers. Ethical and legal challenges of PA are often odious and unmet to the standards. This study was designed to assess perceptions, knowledge, and practices of healthcare professionals towards pharmaceutical advertisement in Pakistan. A survey-based descriptive cross-section study, of 764 sample records and analyzed by SPSS, version 21. A Chi-square test was performed (p ≤ 0.05) to find out differences among variables. We found  34.8% (n=266) physicians, 8.4% (n=64) dentists, 13.6% (n=104) hospital pharmacists, 15.7% (n=120) community pharmacists, 8.4% (n=64) regulatory pharmacists, 8.3% (n=63) marketing pharmacists and 10.9% (n=83) physicians and pharmacists from distributions and other relevant fields participated in this study. The result showed that 81.4 % (n=622) believed that medical advertisements should seek government approval, 71.3% (n=545) assumed that only registered drugs could be advertised. 34.0% (n=260) answered only prescription drug could be advertised. 7.2% (n=284) showed a negative response towards advertised drugs. 33.0% (n=252) answered that advertising encourages the patients to decide on their choice of a drug without the help of a healthcare professional, while 31.4%(n=240) of the respondents were agreed that advertising provided reliable information regarding a medicine. 36.4% (n=278) of respondents were agree that advertisements increased drugs cost. 32.7% (n=250 and 37.4% (n=286) answered that patients buy an advertised drug without referring a doctor. This study concluded that the awareness regarding PA was low among the healthcare professionals in Pakistan. Healthcare personals were in the favor of advertisement, regardless of little knowledge about the current advertisement rules in the country. Comparatively, Pharmacists have  better knowledge of PA  than physicians do.
Noire n'est pas mon métier ou un autre appel des Indigènes de la République
Authors: Keubeung Gerard
Published: May 2021

Le présent article voudrait analyser L’ouvrage Noire n’est pas mon métier qui regroupe les récits et expériences de seize actrices françaises noires et métisses. S’inscrivant dans le prolongement de la réaction des acteurs afro-américains qui protestaient en 2016 contre leur absence de la liste des nominés pour la cérémonie des récompenses des oscars, les seize contributrices décrivent les discriminations dont elles sont victimes et les difficultés dont elles font face dans l’exercice de leur métier d’actrice. En inscrivant cette publication dans le contexte socio historique de la société française de la fin du siècle dernier marqué par la guerre des mémoires, les émeutes dans les banlieues des grandes villes et le débat sur l’identité nationale, je postulerai que les revendications de ces actrices se situent dans la mouvance générale tracée par « les Indigènes de la République » qui refusent d’être cantonnés dans l’arrière-cour de la république. En revisitant les stéréotypes, les discriminations, et tout le mécanisme d’invisibilisation des actrices noires dans le cinéma français, nous lirons cet ouvrage comme une tentative de prise de parole de la femme noire triplement subalterne et condamnée à une bataille permanente pour s’affirmer comme une humanité et avoir ainsi part à ce que Jacques Rancière appelle « le partage du sensible. »

Discrimination - Cinéma- Indigènes - Noire - Actrice - Exclusion
Editorial
Authors: Dusaillant-Fernandes Valérie
Published: May 2021

Editorial, Voix plurielles 18.1 (2021)
Mbonimpa, Melchior. Au sommet du Nanzerwé il s’est assis et il a pleuré
Authors: French French
Published: May 2021

Compte rendu d'Au sommet du Nanzerwé il s’est assis et il a pleuré (Melchior Mbonimpa)
Lord, Denis. Jack est scrap
Authors: French French
Published: May 2021

Compte rendu de Jack est scrap (Denis Lord)
À pas calfeutrés (2020) ; En cet aujourd’huis rouvert (21 mars 2021)
Authors: Charlebois Eric
Published: May 2021

Poèmes inédits d'Eric Charlebois : "À pas calfeutrés" (2020) et "En cet aujourd’huis rouvert" (21 mars 2021)
Summarising a Framework for the Certification of Reliable Autonomous Systems
Authors: Fisher Michael , Mascardi Viviana , Rozier Kristin Y , Schlingloff Bernd-Holger , Winikoff Michael , Yorke-Smith Neil
Published: May 2021

No description supplied
Exit Strategy Percepatan Penanganan Corona Virus Disease 2019 (Covid-19)
Authors: Abdurahman Abdurahman Abdurahman
Published: May 2021

Penyebaran corona virus disease (covid-19) belum menunjukkan tanda-tanda akan menurun. Laporan WHO 19 agustus 2020 angka terkonfirmasi positif lebih dari 22 juta dan meningggal 778.000  orang, sedangkan di Indonesia sendiri  per 19 agustus kasus 144.945 terkonfirmasi, 98.657 sembuh dan 6.346 meninggal. Wilayah Jawa Timur yang terkonfirmasi per 18 agustus 28.551, sembuh, 21.632, dan 2.055 , serta dirawat 4.864. Sedangkan di kabupaten sampang pasien positif pertanggal 18 agustus mencapai 219 Terkonfirmasi, 13 Meninggal, 186 sembuh dan 18 dirawat. Kabupaten Sampang merupakan daerah terakhir di Jawa Timr yang diketahui ada pasien positif dari klaster pasar tradisional, sebelumnya daerah ini selama kurang lebih dua bulan bersama kabupaten sumenep bertahan dengan zona hijau.
STRATEGI PENGEMBANGAN WIRAUSAHA MANDIRI MAHASISWA DI MASA PANDEMI COVID-19
Authors: Khoiron Ahmad Mustamil
Published: May 2021

Penyebaran virus COVID-19 sangat berdampak diseluruh aspek kehidupan masyarakat, khususnya dibidang ekonomi diseluruh dunia termasuk di Indonesia. Tidak terkecuali pada pelaku usaha mahasiswa yang telah dibina oleh Program Pengembangan Kewirausahaan (PPK) Fakultas Teknik Universitas Negeri Semarang tahap pertama. Program Pengembangan Kewirausahaan (PPK) merupakan salah satu program pengabdian kepada masyarakat yakni dibidang pengembangan usaha mandiri mahasiswa khususnya. Program PPK bertujuan untuk mengembangkan jiwa dan potensi mahasiswa dalam berwirausaha dengan bersinergi dengan penguasaan teknologi yang dimiliki oleh mahasiswa. Metode pelaksanaan kegiatan PPK adalah secara demonstrasi dan pembinaan tenant. Proses pelaksanaan terdiri atas tujuh tahapan yakni: (1) rekruitment tenant dan pembentukan kelompok usaha, (2) webinar study banding, (3) webinar sertifikasi produk dan kegalitas usaha, (4) pemberian dana stimulus tenant, (5) pendampingan usaha, (6) monitoring dan evaluasi. Berdasarkan pelaksanaan Program Pengembangan Kewirausahaan (PPK) di Fakultas Teknik Universitas Negeri Semarang diperoleh hasil bahwa terdapat wirausaha mahasiswa yang mampu bertahan dan stabil pada masa pandemi COVID-19 antara lain dibidang kuliner, jasa kecantikan, dan produk busana. Pendampingan kewirausahaan mahasiswa yang dilakakukan memberikan sumbangsi dalam penguatan kegiatan berwirausaha dimasa pandemi COVID-19.
PEMBUATAN SPOT MURAL SEBAGAI ATRAKSI WISATA DI DESA TOYOMARTO KECAMATAN SINGOSARI KABUPATEN MALANG
Authors: Fauzi Nanang Bustanul
Published: May 2021

Abstrak Pengabdian kepada masyarakat ini difokuskan untuk  membangun citra desa Toyomarto sebagai desa Air melalui media spot mural. Pengabdian ini didasari  dari keberadaan Desa Toyomarto yang selama ini telah memiliki situs bersejarah yang menjadi tujuan wisata, yaitu Situs Sumberawan. Melihat potensi sejarah dan budaya yang kental pada Desa Toyomarto serta belum terdapatnya spot foto yang instagrammable, kami berupaya memberikan kontribusi berupa pembuatan mural berbasis budaya dan sejarah bagi Desa Toyomarto. Mural tersebut diharapkan dapat menjadi spot foto yang menambah daya tarik wisatawan untuk mengunjungi Situs Sumberawan sekaligus memberikan pembelajaran sejarah dan budaya bagi masyarakat dan para pengunjung. Hasil pengabdian berupa pembuatan spot mural memberikan dampak positif bagi masyarakat desa Toyomarto. Dampak positif dari pembuatan spot mural ini adalah dapat meningkatkan  kesejahteraan ekonomi masyarakat secara tidak langsung tanpa meninggalkan esensi pembelajaran sejarah dan budaya.Kata Kunci: mural, atraksi wisata, toyomarto Abstract  This community service is focused on building the image of Toyomarto village as an Air village through spot mural media. This service is based on the existence of Toyomarto Village which has had historical sites which have become tourist destinations, namely the Sumberawan Site. Seeing the historical and cultural potential that is thick in Toyomarto Village and the absence of instagrammable photo spots, we try to make a contribution in the form of making a culture and history-based mural for Toyomarto Village. The mural is expected to be a photo spot that adds to the attractiveness of tourists to visit the Sumberawan Site as well as provide historical and cultural lessons for the community and visitors. The result of dedication in the form of making a spot mural has a positive impact on the people of Toyomarto village. The positive impact of making this spot mural is that it can improve the economic welfare of the community indirectly without leaving the essence of historical and cultural learning.Keywords: murals, tourist attractions, toyomarto
Covid 19 Outbreak and Financial Statement Quality: Evidence from Central Java
Authors: Nurcahyono Nurcahyono , Sukesti Fatmasari , Alwiyah Alwiyah
Published: May 2021

This study aims to analyze and find empirical evidence that the Covid 19 pandemic will affect the quality of financial reports and what factors affect the quality of government financial reports. The variables used in this study are competence, compliance with government accounting standards, external pressures, environmental uncertainty, internal control systems, and the quality of financial reports. The population of this study was accounting or finance staff who served in 48 SKPDs in the Central Java Provincial Government. The sampling technique used was simple random sampling, this sampling technique was chosen because the study population was homogeneous. Analysis of research data using the WarpPLS 7.0 application as well as used for hypothesis testing. The results show that competence, compliance with government accounting standards has a positive effect on the quality of financial reports, while external pressure has no effect and environmental uncertainty has a negative effect on the quality of financial reports. Internal control is able to strengthen the relationship between competency variables and compliance variables with the quality of financial reports and weaken the relationship between internal pressure variables and environmental uncertainty variables on the quality of local government financial reports. The implication of this research is that the quality of financial reports can be achieved when the work structure has good competence, complies with government accounting standards, is able to anticipate uncertainty and applies internal controls properly.
Effect of Accounting Lecturer Behavior on the Level of Online Learning Outcomes Achievement
Authors: Kustono Alwan Sri , Winarno Wahyu Agus , Nanggala Ardhya Yudistira Adi
Published: May 2021

Changes in learning models in reaction to the COVID-19 pandemic have a significant impact on how accounting is taught. The objective of this study was to compare the differences in learning outcomes before and during the pandemic. A total of 367 research participants were collecting and the data were analyzed using the Partial Least Square – Structural Equation Modelling approach. Additional testing to control the demographic variable shows that the demographic variable is not a determinant of learning outcome achievement. The results showed that anxiety reduces the ease of use, and external control perception positively affects it. The theoretical implication is that the online learning outcome increases depending on user behavior variables. Technology acceptance variables are a mediation between personality variables and online learning. Other constructions of the TAM model have been empirically proven. The level of achievement before the pandemic is higher than during the pandemic. These results indicate that the implementation of online learning is more effective if it has been prepared from the beginning. The practical implication is to achieve a good outcome. A university must reduce anxiety and increase the positive control of the external perception of each lecturer.
Plan de mejora docente en las prácticas educativas virtuales en la Educación Superior en tiempo de pandemia en Paraguay
Authors: Rejalaga Noguera Larissa , Córdova Rangel Stefanny , Ayala Liliana Alejandra , Gómez de Meza Elida Gómez de Meza , Miranda María de los Ángeles
Published: May 2021

En Paraguay se escribe una nueva historia en el ámbito educativo debido a la presencia del virus SARS-CoV-2, causante de la enfermedad COVID-19. Este acontecimiento, dio lugar a la Resolución CE-CONES, Nº 04/2020 del 21 de marzo 2020 “Que establece la facultad de las instituciones de educación superior para aplicar herramientas digitales de enseñanza-aprendizaje”, por la necesidad de implementar acciones preventivas ante el riesgo de expansión del coronavirus en el territorio nacional, implementado por el Decreto de Presidencia 3456 16 de marzo de 2020. En virtud de atender el nuevo paradigma de la educación, se hace necesario contar con mejoras en las prácticas educativas. Por consiguiente, la combinación de estrategias didácticas fundamentadas con teorías del aprendizaje permite diseñar y configurar procesos pedagógicos que implementen las tecnologías, con el objetivo de facilitar la asimilación de los conocimientos y el desarrollo socioemocional del alumno. En este contexto, el presente trabajo tiene como propósito fundamental contribuir en proporcionar a los docentes universitarios diez propuestas para optimizar y garantizar el proceso de aprendizaje desde la modalidad virtual, formuladas a partir de teorías pedagógicas.
La posesión notoria del estado civil de hijo en el derecho indígena chileno como manifestación del derecho a la identidad
Authors: Astudillo Meza Constanza
Published: May 2021

La institución de la posesión notoria es un medio supletorio para acreditar en general el estado civil (hijo, hija, marido). En este sentido en el Código Civil chileno en su art. 200, regula esta institución, indicándose que los elementos para acreditarla son: nombre, trato y fama, y se materializa en probar que por cinco años continuos se le trató como hijo o hija mediante un conjunto de testimonios y antecedentes o circunstancias fidedignas que la establezcan en forma irrefragable. Sin embargo, en el art. 4 de Ley N°19.253, que establece “normas de protección, fomento y desarrollo indígena” encontramos una norma que viene a disciplinar la posesión notoria respecto de los indígenas indicándose que “bastará para acreditar la posesión notoria del estado civil cualquier testimonio que se dé en una gestión judicial o ante la autoridad de la Corporación Nacional Indígena” como se puede observar nada se dice acerca de los tres elementos mencionados. Siguiendo el razonamiento anterior debemos concluir que si estamos ante niños, niñas y adolescentes (NNA) indígenas deberá prevalecer la norma especial regulada en la ley de la materia en específico, por sobre lo dispuesto en el Código Civil. El argumento para sostener lo anterior no es solo el criterio de especialidad de la norma, sino el derecho a la identidad de los NNA indígenas previsto en los art. 7 y 8 de la Convención Internacional sobre los derechos de los niños (en adelante CIDN), hacemos presente que estas normas no definen el derecho a la identidad por lo que la doctrina ha indicado que mediante éste se distingue a un individuo de otro, y se le da una fisonomía propia. Nos parece adecuado agregar que el artículo 8 de la CIDN, consagra el deber de los Estados a preservar la identidad de los NNA y sus relaciones familiares, lo que está en armonía con lo dispuesto en la normativa indígena, resultando ésta una manifestación del derecho a la identidad, pues se buscar preservar los orígenes y cultura por sobre la imposición de la reglamentación civil en materia de filiación, reconociéndose de esta manera la historia de vida de cada NNA.
Principio de la Buena Administración en Paraguay
Authors: Galeano Rodríguez Blas Javiaer
Published: May 2021

Se centra principalmente en reconocer, no solo al principio de la buena administración como principio, sino también como un derecho fundamental que sirve de límite al poder público, ciñendo en este ámbito, la percepción de confianza de los ciudadanos hacia ella, la cual es baja y por ende negativa, con la reforma se quiere aumentar la transparencia en materia de gestión y participación ciudadana en igualdad de derechos. Administrar significaba regir o gobernar, lo cual se confundía con las funciones políticas, gubernamentales y religiosas encomendadas al jefe de la tribu, lo que se entiendo, por ahora, la buena administración a la estructura y organización con una connotación ética en el cumplimiento del fin que justifica su existencia, jurídicamente, como lo define el Prof. Dr. Ramírez Candia “el conjunto de entidades y órganos que se establecen en un orden jurídico determinado para la realización de las actividades administrativas del Estado”. En este contexto administración pública debe ser ejercida en el marco de los proscriptos por las leyes, utilizándola de manera razonable con los recursos disponibles para la consecución de sus fines.
Análisis de efectos psicológicos en tres familias integrantes de Empresas Familiares y posibles estrategias de afrontamiento
Authors: Aponte Atílio A. , Rojas Benítez Aldo Rubén
Published: May 2021

Este trabajo se propuso estudiar, a través del análisis de los efectos psicológicos, la consecuencia en la salud mental de los miembros de las familias propietarias que trabajan en una empresa familiar, así como de los colaboradores cercanos. Según el carácter de la empresa: sea educativa, comercial o industrial; cada una de ellas tiene sus propias características, tanto en el gerenciamiento general como en la carga emocional que transfiere el tipo de trabajo que realizan.
Protocolo de informe para pacientes con presunción de presencia de variante factor Rh d / du positivo
Authors: Brítez Myrian Beatriz , Ortiz Alcides Alejandro , Martínez Gloria
Published: May 2021

Para realizar pruebas serológicas de grupo sanguíneo son necesarios buenos conocimientos, tanto teórico como práctico. En la formación del personal debe hacerse también hincapié en las precauciones necesarias para reducir el riesgo de errores de manipulación, así como en las técnicas a ser aplicada. Un error de manipulación en la transfusión de sangre puede ser una importante causa de daños o incluso defunción. El antígeno Du es una variante débil del antígeno D que tiene interés desde el punto de vista transfusional. Este antígeno aglutina débilmente o no aglutina con los anticuerpos Anti-D habituales y, por tanto, es posible clasificar erróneamente al portador de este antígeno como Rh negativo. La transfusión de esta sangre a una persona Rh negativo produciría sensibilización Anti-D. Por este motivo, siempre ante un Rh negativo se investiga la presencia del antígeno Du mediante el Test de Coombs. El antígeno D incluye los tipos de categoría D, D parcial y D débil, que son importantes porque la a la inmunización anti-D puede ocurrir en algunas personas, pero no en todas, que expresan un alelo Rh D variante. En la actualidad, existe poca información prospectiva sobre la prevalencia de variantes D entre pacientes obstétricas y potenciales receptores de transfusiones.
Acceso a la universidad de jóvenes itaugueños de la zona urbana
Authors: O'Hinggins Salinas Teresa
Published: May 2021

La franja etaria comprendida ente 15 a 29 años ha aumentado según el último periodo censal (Atlas Demográfico del Paraguay, 2012), partiendo de esto para justificar que gran cantidad de jóvenes deben acceder a estudios superiores. El trayecto de la educación media a la universitaria conlleva conflictos socioeconómicos, que exige a los padres un esfuerzo mayor para que su hijo adolescente prosiga sus estudios. Itauguá cuenta con seis universidades privadas, razón por la cual se justifica aún más la necesidad de conocer porqué tantos jóvenes no cursan estudios universitarios.