bluuebunny/crossref_metadata_2025 huggingface dataset:
KEDUDUKAN ANAK TIRI BEDA KASTA TERHADAP PEWARISAN
Authors: Dewa Gede Edi Praditha  , Made Hendra Wijaya
Published: November 2022

Pembahasan di dalam artikel ini mengenai kedudukan anak tiri yang memiliki kasta yang berbeda terhadap hak pewarisan yang dimiliki di dalam hukum adat yang ada di Bali. Kajian di dalam artikel ini menggunakan metode penelitian hukum normatif yang bertujuan untuk mengetahui serta menganalisis keberadaan anak tiri beda kasta di Bali yang berkaitan dengan proses pewarisan dalam tatanan hukum adat Bali, mengingat dalam keberadaan kasta dan sistem kekerabatan di Bali yang memiliki keunikan tersendiri dan memiliki wilayah otonom yuridisnya tersendiri. Di sisi yang lainnya, maraknya peristiwa pernikahan yang dilakukan oleh seorang wanita yang telah memiliki anak dan menikah kembali dengan laki-laki beda kasta menimbulkan konflik terkait ahli waris dalam kekerabatan adat yang ada di Bali masih sering terjadi, hal tersebut dapat dikatakan merupakan sebuah bom waktu di dalam kehidupan sosial adat di Bali yang hanya tinggal menunggu waktu untuk meledak menjadi sebuah permasalahan yang perlu dibahas dengan serius.
HAK-HAK NARAPIDANA ANAK DI LEMBAGA PEMBINAAN KHUSUS RIGHTS OF CHILDREN IN SPECIAL CORRUPTION INSTITUTIONS
Authors: I Nyoman Gede Sugiartha
Published: November 2022

Crimes against children are currently increasing in Indonesia, childrenare one of God's creations and at the same time are the children of the family. AsGod's creation, children under 18 years old or unmarried are still unstable intheir behavior, their unstable emotions should get full attention in correctionalinstitutions. This study aims to analyze the regulation of the child educationsystem in special coaching institutions and legal protection for child prisoners inspecial coaching institutions. This type of research uses an empirical method,using a Legislative and Conceptual approach. The problems raised; 1. Children'sRights in Prisoners Educated in Special Guidance Institutions. 2. Regulation ofchildren's rights in the criminal justice system in Indonesia. 3. ObstaclesExperienced by Officers in Fostering Child Prisoners in Special GuidanceInstitutions. Discussions and discussions include; Children's rights in the justiceand education system are regulated in the Law of the Republic of IndonesiaNumber 11 of 2012 concerning the Child Criminal Justice System while the legalprotection of children is regulated in the Law of the Republic of IndonesiaNumber 35 of 2014 amendments to Law Number 23 of 2002 About ChildProtection. Correctional officers must understand better and must be adapted tothe conditions and situation of Indonesia without ignoring the methods or rightsthat should be obtained by children who are in conflict with the law by othercountries that should be considered and imitated.
Reaksi Investor Pada Saham Perusahaan Sub Sektor Perhotelan, Restoran Dan Pariwisata Pada Masa Pandemi Covid
Authors: Krismawati Via , Maslichah Maslichah , Sudaryanti Dwiyani
Published: November 2022

Covid Pandemic has multidimensional effect to economic activity. It affects investor reaction to the prospect of industrial sector in Indonesia.  The objective of this study aims to study the investor reaction during Covid pandemic on the shares of hospitality industry, restaurant, and tourism subsector The population of this research is hospitality industry, restaurant, and tourism subsector on the BEI with purposive sampling as its technique. The proxy of investor reaction is Average Trading Volume Activity in monthly basis. This study compares two period of reaction, 7 months before Pandemic and 7 months during Covid Pandemc. The data were analyzed using paired t test. The results showed that there was no difference between before and during Covid Pandemic. Investors are still positive on the prospect of hospitality industry, restaurant, and tourism subsector. It implies on a need of a supportive policy from government to keep the investor’s trust, such as issuing tax amnesty for those industry.
Pengukuran Kinerja Keuangan Perusahaan Terhadap PT Semen Indonesia (Persero) Tbk Tahun 2019-2021 Menggunakan Analisis Common Size
Authors: Fauziyah Risma Hasna , Hari Sulistiyo
Published: November 2022

The Indonesian economy has experienced growth or decline due to several things, one of which is by State-Owned Enterprises. Financial statements can provide useful information as a tool to understand the financial performance of a company. The purpose of this study is to analyze the financial performance of PT Semen Indonesia (Persero) Tbk which is listed on the Indonesia Stock Exchange from 2019 to 2021 in terms of financial statements with total assets or liabilities presented in the balance sheet and income statement using common size analysis. The results of quantitative descriptive research using processed secondary data indicate that the company is still relatively healthy and the company's financial performance on the balance sheet is in a fairly good condition. However, the financial performance on the income statement shows that the marketing strategy is less effective in terms of increasing revenue and has not been able to provide long-term profitability.
Akuntabilitas dan Transparansi Pengelolaan Badan Usaha Milik Desa “Jaya Tirta”
Authors: Ariski Nanda Ayu , Asim Asy'ari Muhammad
Published: November 2022

Village-Owned Enterprises are business entities formed and established by the village with the aim of managing the potential of the village in order to strengthen the village economy. As a new entity, it is important for BUMDes to pay attention to aspects of good governance, especially accountability and transparency, which are the main keys in business management in order to avoid misuse of funds that can result in the BUMDes business stalling. This study was conducted with the aim of analyzing the extent to which the principles of accountability (process and output) and transparency are applied in the management of BUMDes Jaya Tirta, Kanor District, Bojonegoro Regency. This research is a case study qualitative research. The types of data used are primary and secondary data. Data collection techniques were carried out through observation, interviews, and documentation by going directly to the research site. The data analysis technique in this study was carried out with a disciplined comparative. The results show that the financial management of BUMDes Jaya Tirta has been carried out in an accountable and transparent manner by BUMDes managers so that it has an impact on the progress and success of BUMDes.
ANALYTICAL MONITORING OF FINANCING THE AGRICULTURAL FORMATION PRODUCTION PROGRAM
Authors: SAVCHUK Vasyl , FEDORCHENKO Krystyna
Published: November 2022

An effective mechanism for financing the implementation of the production program can be created only if the timely management of compliance with the organization and technology of production, the necessary information used for quality assessment and operational forecasting of this process. For the system analysis of the performance of the production program, it is necessary to use as much as possible various data sources which are formed both at the enterprise and out of it. It is important to process them in a timely and well-thought-out way to identify problematic moments at the very beginning of their origin. This will be facilitated by the system of analytical monitoring as an effective tool for preparing relevant information for the development and adjustment of management decisions related to financing the production program through the receipt of own, borrowed and borrowed funds and their rational use to optimize production processes. It is proved that the adequacy and timeliness of financial resources is a determining factor in the successful implementation of the production program. This is especially important for agricultural production, as all technological processes must be performed in the optimal time. It is very important to ensure self-financing of the production program, as this is a prerequisite for reducing the cost of production and increasing its competitiveness. Only under such conditions can the system of analytical monitoring be considered effective, which provides the high-quality and timely formation of information about the object of observation, and its analytical understanding as a necessary prerequisite for the development and adoption of effective management decisions.
Further research should be aimed at timely receipt of objective information on compliance with the timing and quality of technological processes, which can be obtained using the benefits of digitalization, and justification of the need for financial resources taking into account organizational and legal forms of economic entities, their production direction, specialization production and its diversification, expanding the search for sources of minimum value for its financing.
Keywords: analytical monitoring; financing; agricultural formations; production program; technology; cash flows; synchronization, management decisions.
CURRENT TRENDS IN RISK MANAGEMENT OF AGRICULTURAL PRODUCTS
Authors: Tiahnyriadno Oleh
Published: November 2022

Introduction. Agricultural producers regularly face price and production risks. Moreover, the strengthening of global free trade and changes in domestic agricultural policy increase the likelihood of adverse events. As price volatility increases revenue volatility, manufacturers are realizing the importance of risk management as a component of their management strategies.
One way to reduce these risks is to use commodity futures and other derivatives. Similar to car insurance, hedging potential costs as a result of a car accident, farmers can use commodity futures markets to hedge the potential costs associated with commodity price volatility. Just as if the profit from a car insurance claim cannot exceed the value of the total amount of insurance premiums, the profit from hedging may not cover the cost of hedging.
The purpose of the article is to scientifically substantiate theoretical positions and methodological approaches and to develop alternative risk management strategies through stock exchange instruments, namely, its derivatives – futures and options.
Results. The importance of theoretical bases formation of risks that can be faced by domestic producers is substantiated. The ways uncertainties occur, stages of their transformation, are explained. The theoretical approach to risk management through the use of futures contracts is systematized. The historical stages of development of using derivatives have been evaluated.
Conclusions. In developed countries, any business activity is unthinkable without risks, so any manufacturer seeks to ensure its risk, including a fixed market. The very time market, on which a particular derivative operates, allows redistributing risks among market participants. The advantage of derivatives is the leverage that allows participants to operate large amounts of risk management funds, including hedging their own products.
Keywords: risk, risk management, hedges, options, futures, derivatives.
DIRECTIONS AND METHODS OF BANKING SUPPORT OF THE ESTABLISHMENT AND REALIZATION OF HIGH-TECH INDUSTRIES POTENTIAL IN THE NATIONAL ECONOMY OF UKRAINE
Authors: RUSHCHYSHYN Nadiya
Published: November 2022

Introduction. The article outlines the features of modern functioning of the banking system in Ukraine in the context of supporting high-tech industries. It is generalized that banks, as a rule, cooperate with businesses that are financially stable and solvent, able to repay their debts quickly. That is why the implementation of the state policy for high-tech industries support in Ukraine is an integral part of building a competitive national economy, ensuring its stability and development.
The purpose of the article is to substantiate directions and methods of bank support for formation and realization of high-tech sectors potential in the national economy of Ukraine.
Results. The sectors of the economy of Ukraine, according to the criterion of their manufacturability and role in the economic growing of the state, are clarified in the article. It is concluded that the strategic directions of Ukraine's economy are high-tech industries with a high share of value added, such as: the field of information and communication technologies, software, pharmaceutical industry, production of high-precision optical medical equipment, aerospace industry. The directions, tools and methods of realization of the state policy of bank support for formation and realization of high-tech branches potential in the economy of Ukraine are defined. The main tools for the development of bank lending, which are focused on taking into account the sectoral specifics of strategic areas of management, are institutional-regulatory, fiscal-investment, financial-economic, structural-managerial, organizational-methodical, social-psychological and information-communication.
Conclusions. The results of research have shown that high-tech sectors of the economy require the development of adequate tools to stimulate its development as a strategic driver of structural reforms and the formation of expanded reproduction processes in the national economy. It is substantiated that the fundamental basis for the development of bank lending in strategic sectors in the economy of Ukraine is the formation of a high level of public confidence in the activities of the banking system.
Key words: structural reform, potential of the banking system, high-tech industries, instruments and methods of state policy, economic system, structural transformations, strategic priorities of state policy.
FORMATION OF MONEY SUPPLY IN WORLD ECONOMY AND MODERN MODIFICATION OF ITS MECHANIZM
Authors: BATYUK Larysa , ONEGINA Viktoriya
Published: November 2022

Introduction. The formation of money supply is influenced by the policy of "cheap money" and the emission of the significant amount of money in the modern world economy. Modification of the money supply mechanism is accompanied by an unprecedented increase of the transactions with derivative financial instruments, accelerated growth of debt in global scale. This modification leads to the global imbalances, including the gap between the financial and the real spheres, increasing risks as to national economies as to world economy.
The purpose of the article is to determine the peculiarities of modern modification of the mechanism of money supply in the world economy and the risks, that this modification causes.
The study used such methods as analysis, synthesis, scientific abstraction, induction to identify the main characteristics of modern modification of money supply; comparison; generalization to make conclusions relating to the evaluation of modern tendencies and the essence of the process of money supply modification.
Results. The concept of "global liquidity" and its modern structure have been specified. The global liquidity has been considered as the total amount of means of payment in world currencies, as well as financial instruments that can be exchanged for these means of payment in the shortest time and with minimal costs. The changes of structure and volume of global liquidity influence on the modification of money supply, imbalances between real and financial sectors of global economy. The peculiarities of the mechanism of modification of the money supply in the world economy are revealed, among these peculiarities are following: growth of possibilities of money multiplication in the system of credit institutions; increasing trade by structured financial products and thus masking the growth of debts; the geographical, quantitative and qualitative imbalances in the supply and demand of global liquidity; increase of Basel standards role in regulating the multiplication of money in the network of commercial banks, and changing the tools of the state monetary policy. Such modification is accompanied by a singular increase of debt in a global scale, possibilities of transformation of private financial institutions debt into public debt, unpredictable fluctuations in cryptocurrencies market, increasing the value of global liquidity through cryptocurrencies, instability of the global financial system, growth of risks of global financial crises.
Conclusions. Further studies of the modification of the money supply mechanism in the world economy should take into account changes in the composition of reserve currencies due to the growth and strengthening of individual economies, the impact on the volume and structure of global liquidity according to Basel III standards, their effectiveness in reducing risks of global financial instability.
Keywords: money, money supply, bank, loan, debt, global liquidity.
DEVELOPMENT OF HUMAN RESOURCES OF THE PUBLIC SERVICE BODY
Authors: BOGOMOLOVA Kateryna , PODOLSKA Olha
Published: November 2022

Introduction. The article presents theoretical generalizations of improving the organizational mechanisms of human resources development by disclosing the content of the concept of human resources in public administration, which reflect the use of modern approaches and tools that can significantly improve the quality and efficiency of public administration decisions for Ukrainian society.
The purpose of the study is to analyze the theoretical provisions and develop practical recommendations for improving the development of human resources of the public service body.
Results. The creation of a new public administration system, based on effective professional activity of personnel holding public office positions, will be an important factor in Ukraine's development as a developed legal European state with a high standard of living, social stability, culture and democracy. Only the implementation of a set of systemic transformations will make it possible to improve the quality of public service, its efficiency and effectiveness, and most importantly, to approach European standards. The main problems of personnel policy of the civil service in Ukraine, the priorities of improving the work of civil servants and the directions of their implementation are highlighted. The urgent need to change the management paradigm in the field of state personnel policy, to develop a model of a sustainable, efficient personnel system, the introduction of new personnel technologies is substantiated. Ways to improve the organizational development of human resources of the public service body are proposed.
Conclusions. It is concluded that the improvement of the human resources potential of the public service is a complex problem that requires the organization of a system of work to improve its efficiency. When building a new model, it is necessary to take into account the processes of forming the core of the staff in a particular institution or organization, adequate and effective adaptation of the employee in the position, the formation of approaches to mandatory effective development of public service personnel, control and elimination of shortcomings related to staff turnover. shortcomings of current legislation.
Key words: personnel potential, priority, public administration, society, mechanisms.
La Pedofilia es un Trastorno Mental y a Veces un Acto Legal: Un Comentario
Authors: Paniagua Freddy
Published: November 2022

En la literatura sobre la salud mental, se presume que si una persona es diagnosticada con trastorno mental de pedofilia con los criterios diagnósticos establecidos por el DSM-5 esa persona está también involucrado en un acto ilegal penalizado por el código penal del país en donde el acto ocurrió. Este comentario argumenta que esa presuposición es parcialmente correcta, y que los profesionales de la salud mental deben revisar cuidadosamente las legislaciones que definen a que edad relaciones sexuales son consideradas legales versus ilegales antes de decidir evaluar, diagnosticar, y tratar personas involucradas en esas relaciones con niños/as en un país determinado. Este argumento es ilustrado con ejemplos de países en las regiones del Caribe (p.ej., Republica Dominicana, Cuba), América Central (p. ej., Panamá, Costa Rica), América del Sur (p. ej., Colombia, Venezuela), América del Norte (Canadá, México, y los Estados Unidos), Asia (p.ej., China, Irán), Europa (p.ej., Francia, España), y África (p.ej., Angola, Nigeria).
Optimization of Adaptive Threshold in Tumor Segmentation Based on I-124 PET/CT NEMA Phantom Study
Authors: Vijayarao Dhanessha , Musarudin Marianie , Said Aminudin
Published: November 2022

Numerous methods have been introduced to segment the thyroid tumors in iodine-124 (124I) Positron Emission Tomography/Computer Tomography (PET/CT) imaging. An adaptive threshold-based is preferable to a manual and fixed threshold-based approach for forecasting accurate and precise tumor volume in real-patient studies, as it was reported to be more resistant to noise and resolution. Manual segmentation was reported to be time-consuming, subjective, subject to inter- and intra-observer variability and prone to segmentation errors [1]. This study aimed to determine the optimal adaptive threshold for thyroid tumor segmentation in 124I PET/CT imaging.

 

The objective of this study was firstly to determine the segmented volume using the standardized uptake value threshold method. Secondly, to compare the adaptive threshold and recovery coefficient (RC) value between the time of flight (TOF) and non-time of flight (non-TOF) PET/CT reconstructions in 124I phantom studies. Finally, to determine the accuracy and RC for 124I PET/CT studies. This study was done by placing NEMA 2012/IEC 2008 PET IQ Phantom and filled with 1 kBq/ml and 20 kBq/ml in its background and sphere each to model tumor background ratio (TBR) 20:1 of 124I PET/CT imaging. The phantom was scanned using TOF and non-TOF PET at 3, 4 and 5 minutes per bed position and reconstructed using 600, 1200 and 2000 beta penalization factors. Image registration, contouring and segmentation were performed using MIM Encore Software. A set of different adaptive thresholds (Tadaptive: 10%-50%) was applied to each sphere in the TBR image of the phantom using the tri-dimensional automatic segmentation tool. The optimal Tadaptive for each of the parameter assessed was defined based on the lowest goodness value calculated. The RC was calculated using mean value and known activity. Finally, the RC against the percentage of maximum was plotted to analyse the descending order of beta penalization factors for time per bed position.

 

Figure 1 shows the image of 124I contoured VOIs on the spheres. The results showed that segmented volumes were not affected by the time per bed position in 124I PET/CT imaging. Table 1 shows the descending order beta penalization factors for time per bed position. Beta penalization factors of 600 to 2000 resulted in either underestimation or overestimation of the measured volume. Comparing TOF to non-TOF PET/CT 124I imaging, consistent and reproducible data were observed for the TOF PET for the three beta penalization factors. Tadaptive of 28.0% consistently gave the lowest goodness value shown by the closest R2 value to one, thus can produce lowest error if it is being used to reconstruct images.

As a conclusion, 28% Tadaptive is suggested as the optimal threshold for 124I TOF PET/CT imaging due to consistent data obtained for all beta penalization factors assessed in this study. The inconsistent data obtained by non-TOF PET thus requires further optimization.
Apoptosis Event in Hela Cells Treated with Cisplatin, Gallic Acid and Combination of Both
Authors: Sazeli Syahirah , Abdullah Hasmah , Hapidin Hermizi , Sulong Sarina
Published: November 2022

Adverse effect of conventional chemotherapeutic agent using single anticancer drugs had led to application of combination therapy in cancer treatments. Combination of polyphenolic compounds and anticancer agent was studied and shown promising outcomes in vitro. In cancer treatment, mode of cell death through apoptosis is one of the targeted approaches in many preclinical drug development studies and has been identified as a key mechanism of chemotherapy-induced cell death. 

 

Hence, this study was conducted to evaluate the apoptosis event of HeLa cells treated with gallic acid (GA) combined with cisplatin (CIS). HeLa cells were treated for 24,48 and 72 hours with CIS and GA at IC50 (Table 1) concentrations, and the combination of CIS and GA (CIS– GA) was chosen based on a previous study (66.73 percent cell inhibition [1]. To compare the anticancer effects of cisplatin and gallic acid individually and in-combination on apoptosis in HeLa cells, flow cytometry assay was carried out. 

According to the findings, during every incubation period, the CIS-GA combination treatment group consistently showed the highest level of antiproliferative activity in HeLa cells, followed by the CIS and GA treatment group. CIS and GA combined treatment response was time-dependent, with an increase in apoptotic cells as incubation time increase (Figure 1). At 72 hours, the combination of CIS and GA treatment showed a significant improvement (74.6%), and improvements were also shown after 24 and 48 hours (56 percent and 60.2 percent).

Taken together, these findings suggest that combination therapy enhances the cell death magnitude in HeLa cells. Additionally, these findings have positive implications for the use of a combination therapy approach in cancer treatment.
Anti-proliferative and Apoptosis Inducing Effects of Gallic Acid on Human Acute Myeloid Leukaemia Cell Lines (HL-60)
Authors: Mohd Roba’ei Dalyana Raisa , Wan Osman Wan Nurfarahin , Mohd Zainudin Hudaa Zulfa , Abdul  Aziz Muhammad Yusran , Tuan Johari Syed Ahmad Tajudin
Published: November 2022

Gallic acid (GA) comes from benzoic acid or, more specifically, 3,4,5-tryhydroxybenzoic, which derives from the phenolic acid of the non-flavonoid part of the polyphenol compound. It is found ubiquitously in various plants and fruits, such as grapes, gallnuts, pomegranates, and tea leaves [1]. Many scientific journals and articles reported on the pharmacological properties of the photochemical like GA, which has antioxidant properties, antimicrobial, anti-inflammatory, anticancer, cardioprotective, gastroprotective, and neuroprotective activity [2]. Moreover, the anticancer properties of GA have been recognised in several cancers, such as lung cancers, oesophageal cancer cells and leukaemia [3].

 

The objective of this study is to examine the anti-proliferative and apoptosis inducing effects of GA on HL-60 cell lines. Six concentrations of GA were made using the stock solution of GA compound dissolved in dimethyl sulfide (DMSO). HL-60 cells were treated with concentrations of 100, 50, 25, 12.5, 6.25, and 3.125 µg/mL and was incubated at three incubation period which were 24, 48, and 72 hours. The quantitative measure was determined with cytotoxicity assay of 3- (4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay and was read by microplate reader at 570 nm. For qualitative measure was through staining with acridine orang (AO) and propidium iodide (PI) and observed the morphological changes of the treated cells.

 

Results from the MTT assays show that GA has cytotoxicity effect on HL-60 cells especially for 72 hours incubation period. The maximal half inhibitory concentrations (IC50) value of GA decreases as incubation period increases. The IC50 of GA were 9.03, 6.76, and 3.65 µg/ml for 24-, 48-, and 72-hours incubation, respectively. The IC50 value of GA (p<0.05) was significantly different for different incubation periods. The morphological changes were seen through the AO/PI staining with the appearance of the cell blebbing, early apoptosis, and late apoptosis.

 

Figure 1 shows early apoptosis (EA), late apoptosis (LA), cell blebbing (CB), membrane loose (MB), nuclear fragmentation (NF), and apoptotic bodies (AB).

 

These findings show that GA has potential as anti-proliferative and apoptosis inducing effects on HL-60 cells line. More research is needed to determine the pathways of apoptosis in HL-60 treated with GA.
Tuberculosis (TB) Mucosal Vaccines: Current Efforts and Future Approaches
Authors: Mohd Asri Nur Ain , Xuan Keh Min , Suppian Rafeah , Mohd Nor Norazmi , Azlan Maryam , Camacho Frank
Published: November 2022

It is now known that the existing vaccination, Bacille Calmette-Guérin (BCG), is unable to stop the global Tuberculosis (TB) epidemic, and TB continues to pose a serious threat to public health [1]. Mycobacterium tuberculosis (Mtb), the causing agent, enters the body by inhalation, causing TB predominantly a respiratory infection [1]. Therefore, there is solid evidence to support the idea that a mucosally administered TB vaccination would be more successful than one administered systemically. Our team in Universiti Sains Malaysia (USM) has been working with several organisations in conjunction with Malaysia’s National Vaccine Roadmap (PPVN) to address this problem as well as the government's goal to produce vaccines that are high-quality, efficient, and secure following the guidelines established by the National Pharmaceutical Regulatory Agency (NPRA).

Therefore, the development of TB mucosal vaccines over the past few years for worldwide as well as in USM is outlined in this presentation. It aims to discuss immunological and practical factors in the development of mucosal vaccines and emphasises some of the current and future approaches in USM.

As a result, it is acknowledged globally that matching the path of infection with the path of immunisation is an appealing strategy for the development of TB vaccines. Several approaches have been made in USM to produce a vaccine candidate that significantly induces mucosal immunity. The design of the study showed the manipulation of IgA, which is a hallmark of mucosal immunity, with multi-epitopes of TB to produce IgA: TB recombinant protein by using goat’s milk as a bioreactor. The concept of oral immunisation in-vivo also is an important approach in our effort to maximise the production of the immune system at the point of entry of bacteria.

In a conclusion, as a boost to a prior respiratory or systemic immunisation, the mucosal method might be more effective. In addition to systemic immunity obtained by injected vaccines, vaccines to induce pathogen-specific IgA are being developed to provide a first line of defence at these entry sites. Therefore, combining these concepts into developing new recombinant vaccine against TB would be a promising alternative.
Is Aquaculture a Success? Evidence from Africa
Authors: Lubembe Sharon Indasi , Okoth Sharon , Hounsounou Hilda R.B. , Turyasingura Benson , Moenga Kelvin O. , Mwalughali Thoko B. S.
Published: November 2022

Globally, human population growth worldwide is something that cannot be controlled, and so there is a need to sustain the needs of a growing population. In Africa, for instance, population projections are made yearly, not even once stagnation is seen. Feeding and nutrition issues, hunger eradication have become a problem with the continuing growth of the population, which in turn is putting a lot of pressure on available resources like capturing fisheries from the lakes, oceans, and rivers, leaving them void. Aquaculture has then proven useful in supplementing the dwindling catch fisheries stocks, which have become incapable of supporting the growing population. Since its introduction in Africa, however, changes have been seen as it has contributed to food security and malnutrition and improved livelihoods by creating jobs and generating income. Currently, diversified products come from aquaculture practices both in inland and freshwaters, ponds, and intensification of aquaculture farming methods, which all put together boost the production to a higher level. Genetics has also been employed to ensure seeds produced for aquaculture are worth being cultured for production. A lot of fisher folks are benefiting both directly and indirectly making a living. Although the contribution of aquaculture is small, sometimes termed insignificant, its growth is steady and it has a promising future as far as its goals (increased protein food production and improved livelihoods of fisher communities) are concerned
MODELLING OF DYNAMIC SYSTEMS USING A NUMERICAL ALGORITHM BASED ON AN ALGEBRAIC SUBSPACE APPROACH
Authors: Bagua Hakim
Published: November 2022

For the purpose of providing a linear model in state space form of a dynamic system which is appropriate for control and optimization research, this paper presents a systematic method based on algebraic notions for dynamical systems modeling from operational data using numerical methods.
School leadership that cultivates collective efficacy: Emerging insights 2022
Authors: Elliott Kerry , Hollingsworth Hilary , Thornton Aiden , Gillies Liz , Henderson Katherine
Published: November 2022

The work of the Menzies School Leadership Incubator suggests we need a new approach to leadership that supports school leaders to better manage transformational change and deepen collaborative capacity necessary to cultivate collective efficacy to improve student learning outcomes. This paper provides a description of the work of the Menzies School Leadership Incubator (“the Incubator’) and insights generated so far. The Incubator has identified five leadership domains which underpin the leadership of Collective Efficacy: Understanding Collective Efficacy; Systems Leadership; Change Leadership; Team Leadership; and Collaborative Capacity.
Prevalence of Piperacillin-Tazobactam induced Hypersensitivity Reaction in Workers of Stallion’s Pharmaceutical Factory at Lahore
Authors: Anwar Ali Sulehri  , Hafiz Muhammad Hammad Yaqub  , Humayun Suqrat Hassan Imam  , Uzma Sagheer  , Muhammad Abubakar
Published: November 2022

BACKGROUND & OBJECTIVE: Piperacillin is an antibiotic that belongs to the ureidopenicillin family. Piperacillin-tazobactam provides cover against gram-positive, gram-negative bacteria and some bacteria of anaerobic nature. It is an extended-spectrum antibiotic and is used along with tazobactam which is an inhibitor of beta-lactamase. The main objective of our research was to identify the hypersensitivity reactions of piperacillin-tazobactam in pharmaceuticals factory and office workers.

METHODOLOGY: A Cross-sectional study was conducted at Stallion Pharmaceuticals (Pvt) Ltd located at Sundar Industrial Estate Lahore, Pakistan, from March to April 2018, after approval from the institutional research committee. All the workers, including factory workers and office workers at Stallion Pharmaceuticals (Pvt) Ltd were included in this study. Data was collected from each respondent by immediate-type skin testing. Data analysis was done by SPSS version 25, the demographic data was evaluated by descriptive statistics, Fisher Exact test was used for comparison and p≤0.05 was taken as significant.

RESULTS: The results of the study presented that hypersensitivity reaction was present in (7.5%) of males and (3.8%) of females. It was also observed that (8.8%) of factory workers had hypersensitivity reactions when they are gone through skin tests, and only (2.5%) of office workers were skin test positive. From the above results (11.2%) of all the respondents developed hypersensitivity reactions and (88.8%) showed no reaction when they were gone through skin tests, which contain 0.1 ml of piperacillin and tazobactam. Fisher exact test was applied, and results showed no significant difference between hypersensitivity reactions among factory and office workers as the p-value was 01.

CONCLUSION: Hypersensitivity reaction to piperacillin-tazobactam was minimal in the factory & office workers, and this was not significant.
Spirituality in Narrative Therapy: A Review Study
Authors: GÜLCAN ÇAKMAK Betül
Published: November 2022

This review study aims to examine narrative therapy’s perspective toward spirituality, the relationship between narrative therapy and spirituality, and the use of spirituality in narrative therapy techniques; the study also reveals what kinds of processes can be followed when working with spiritually or religious-oriented clients using a case example. Narrative therapy is a postmodern therapy approach that aims to understand individuals’ identities, personalities, lives, and relationships through the stories they create. This approach gives importance to understanding the meanings individuals ascribe to both their own life stories as well as their personal relationships. Spirituality plays an active role as a part of individuals’ stories by adding meaning and purpose to individuals’ lives and their relationships and for this reason has an important place in narrative therapy. Narrative therapy places emphasis on both understanding the meanings individuals ascribe to their stories as well as re-authoring these stories in a functional way using certain techniques. Spirituality plays a role as an important resource in re-authoring the individual’s story through narrative therapy’s techniques. By emphasizing the role of spirituality in narrative therapy, this study will both contribute to the literature on narrative therapy as well as provide a perspective on how spirituality can be used in this approach.
Well-Being and Spiritual Intelligence Predict Attitudes of Adolescents’ Towards Violence
Authors: ERDURAN TEKİN Özge , EKŞİ Halil
Published: November 2022

In this study, it is aimed to examine the relationships between the well-being, spiritual intelligence and attitudes of adolescents living in Turkey towards violence. The sample of the study consists of 466 high school students (194 girls, 272 boys) aged between 14 and 19, selected using the convenience sampling method. In the study, “Scale for Spiritual Intelligence”, “Five-Dimensional Well-being for Adolescents (EPOCH) Scale” and “Attitude towards Violence Scale for Adolescents” and demographic information form were used as measurement tools. Hierarchical regression analysis was used to test the predictiveness of adolescents’ well-being and spiritual intelligence on their attitudes towards violence. According to the findings obtained from the research, there is a moderately negative and significant relationship between attitude towards violence and well-being. It is seen that there is a low negative and significant relationship between attitude towards violence and spiritual intelligence. It was identified that there is a moderate positive and significant relationship between well-being and spiritual intelligence scores. The well- being variable explaining 32% of the attitude scores towards violence was first included in the staged multiple regression analysis performed. And in the second stage, the spiritual intelligence variable, which contributes 2% to the explained variance, was also included. When the total variance explained is examined, it is seen that the variables of well-being and spiritual intelligence together explain 34% of the total variance in the attitude scores towards violence. This finding shows us that the change in well-being and spiritual intelligence scores predicts the change in the scores of the attitude towards violence.
Strafregister- und Tilgungsgesetz
Authors: Eder-Rieder Maria
Published: November 2022

Mit den Änderungen des Zweiten und Dritten Gewaltschutzgesetzes Die Eintragung strafrechtlicher Verurteilungen und deren Löschung durch eingetretene Tilgung, aber auch deren Auskunftsbeschränkung sind wichtige kriminalpolitische Instrumente. Sie dienen einerseits der Evidenthaltung früherer Verurteilungen als Hilfe zur Deliktsfindung, der konkreten Strafbemessung und Sanktion, andererseits sollen sie zur Resozialisierung des Verurteilten beitragen. Diese Rechtsmaterien werden im Strafregistergesetz 1968 dem Tilgungsgesetz 1972 geregelt, die seit der 1. Auflage (2008) wesentliche Änderungen durch das Zweite (2009) und Dritte Gewaltschutzgesetz (2019) erfahren haben. Dieses Werk enthält eine Kommentierung beider Gesetze auf dem Rechtsstand von August 2022 sowie aktuelle Beispiele aus der Judikatur. Außerdem werden die rechtsgeschichtliche Entwicklung und die wesentlichen gesetzlichen Grundlagen der Strafregisterführung bzw die Voraussetzungen und Folgen einer Tilgung behandelt.
USING NON-INVASIVE METHODS FOR EVALUATING MYOCARDIAL ISCHEMIA IN ASSESSMENT OF THE FUNCTIONAL SIGNIFICANCE OF INTERMEDIATE CORONARY ARTERY STENOSES IN PATIENTS WITH CHRONIC ISCHEMIC HEART DISEASE
Authors: Darenskiy D. I. , Gramovich V. V. , Zharova E. A.
Published: November 2022

Key points of using non-invasive methods for evaluating myocardial ischemia (exercise electrocardiogram, stress echocardiography, single photon emission computed tomography and myocardial perfusion imaging with stress-test) in clinical practice to determine the functional significance of intermediate coronary artery stenoses (50-70% of the vascular lumen) are discussed in the review.
Over leven met een lage status
Authors: van der Waal Jeroen
Published: November 2022

Less-educated citizens report relatively low trust in institutions like politics, the judiciary and science, and find it harder to navigate these than more highly educated citizens. They also more often behave unhealthily and more frequently experience illnesses, and consequently die earlier. A pressing question is how to explain all these well-established educational divides, found in the Netherlands as well as many other western countries. In this inaugural lecture On life with low status, Jeroen van der Waal explores which role status differences play in that regard. How does feeling looked down upon because of their lifestyle shape less-educated citizens’ thinking, feeling, and acting? And how does that feeling explain their substantial differences with more-educated citizens when it comes to health, health-related behaviours, and political preferences? Jeroen van der Waal sketches an interdisciplinary research program that enables to answer those questions. It combines insights from political science, psychology, public health, and sociology, and enriches sociological survey and experimental research with physiological research on stress and emotions, and social-psychological research on implicit associations with lifestyle attributes. This promises to provide crucial insights for various scientific debates in a wide range of research fields, and for optimizing communication between institutional professionals on the one hand, and less-educated citizens, patients, and pupils on the other.Foto: Bob Bronshoff
TRAJECTORY PLANNING ALGORITHM FOR MERGING CONTROL OF HETEROGENEOUS VEHICULAR PLATOON ON CURVE ROAD
Authors: Bian Chentong , Yin Guodong , Xu Liwei , Zhang Ning
Published: November 2022

The main goal of this study is to propose a trajectory planning algorithm for the merging control of heterogeneous vehicular platoons. Merging control is essential for the application of vehicular platoons, by which vehicles can be coordinated to form a platoon in a lane. While most previous researches on merging control only considered the operation on straight roads and ramps. Few studies have investigated the merging operation on curve roads, which may hinder the application of platoons on general traffic environment. In this study, a trajectory planning algorithm is proposed for the merging control of heterogeneous vehicular platoons on curve roads with constant radius. The proposed algorithm consists of two stages for the operation of merging: the first stage is to align the vehicles in each lane to form a structure with a certain clearance; the second stage is to conduct a lane changing manoeuvre for each merging vehicle to form a platoon in a lane. In the proposed algorithm, the dynamic limits of speed and acceleration are considered. The distance of each vehicle can be guaranteed to avoid undesired collisions. Two simulations are carefully conducted for the merging control of heterogeneous vehicular platoons on a curve road to demonstrate the effectiveness of the proposed algorithm. The results of simulations indicate that the proposed algorithm is capable of the merging control of platoons on a curve road.
Phylogeny of Mesitiinae (Hymenoptera: Bethylidae): assessing their classification, character evolution and diversification
Authors: Barbosa Diego N. , Hermes Marcel Gustavo , Lepeco Anderson
Published: November 2022

We present the first phylogenetic hypothesis for Mesitiinae based on 112 morpho-structural characters and 61 species. The results did not support Argaman’s tribal classification for Mesitiinae, since no tribes were found to be monophyletic. Anaylax was found to be paraphyletic, and Gerbekas, Heterocoelia, Parvoculus, Pycnomesitius, Sulcomesitius, Zimankos were found to be polyphyletic. Two new genera are proposed and described: Hadesmesitiusgen. nov. and Brachymesitiusgen. nov.; Botoryan is considered as a junior synonym for Zimankos. Three species status are revalidated; and 11 species combinations were proposed, so that all genera are now monophyletic. The results indicate the thickness of integument in Mesitiinae could be related to their protection against their hosts.
Amolops putaoensis Gan, Qin, Lwin, Li, Quan, Liu & Yu, 2020, a newly recorded torrent frog for China
Authors: Zhang Yin-Peng , Liu Xiao-Long , Stuart Bryan L. , Wu Dong-Yi , Wang Yu-Fan , Che Jing , Yuan Zhi-Yong
Published: November 2022

Amolops putaoensis is a recently described torrent frog species from A. monticola group that is known only from its type locality, northern Myanmar. We compared morphology and mitochondrial DNA sequence data from ten recently collected adult male specimens from the upper Dulong River System in Gongshan County, Yunnan Province, China, to the original description of A. putaoensis. Both datasets strongly supported referring the Chinese specimens to A. putaoensis, extending the known range of this species by approximately 133.7 km distance into China. Molecular phylogenetic analyses recovered A. putaoensis to be closely related to A. aniqiaoensis, A. kohimaensis, A. monticola, and A. adicola. We use the newly collected Chinese specimens to expand the morphological description of the species.
Three new species of Diploderma Hallowell, 1861 (Squamata, Agamidae) from the Hengduan Mountain Region, south-western China
Authors: Liu Shuo , Hou Mian , Rao Dingqi , Ananjeva Natalia B.
Published: November 2022

Three new species of Diploderma are described from the Hengduan Mountain Region in south-western China, based on morphological and genetic data. The first new species from Yulong County, Yunnan Province is morphologically most similar and phylogenetically closely related to D. brevicauda, but it can be diagnosed from the latter by having a relatively longer tail; the second new species from Xiangcheng County, Sichuan Province is phylogenetically closely related to D. bowoense, but it can be diagnosed from the latter by the absence of a distinct gular spot; and the third new species from Yongsheng County, Yunnan Province is phylogenetically closely related to D. yulongense, but it can be diagnosed from the latter by having different colourations of the ventral and ventrolateral surfaces of the body. Taxonomy and diversity survey are the basis of species conservation, our discoveries contributing to better conservation of the species of this genus.
A new digamasellid mite of the subgenus Longoseiulus Lindquist (Acari, Mesostigmata) from Slovakia
Authors: Mašán Peter
Published: November 2022

A new digamasellid mite, Longoseius (Longoseiulus) disparisetussp. nov., was described from females found in the wood detritus of tree cavity of freshly felled elm (Fraxinus sp.) in a park in southwestern Slovakia. The new species differs from known congeners by the number of setae on some leg segments (genu II with eight setae, tibiae II and III with seven and six setae, respectively) and by the unusual presence of three pairs of conspicuously shortened setae (J3, J4, and Z3) on the posterior dorsal shield. In other known Longoseiulus species, the genu II has 11 setae, the tibiae II and III have 10 and seven setae, respectively, and almost all dorsal setae are of similar length (except for the elongated Z4 and S4), none of which is formed as a microseta. A dichotomous key for females is provided to identify species classified worldwide in Longoseiulus.