bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance Comparison of Machine Learning Methods in Discovery of BACE-1 Inhibitors in Alzheimer's Disease Therapy
Authors: Daş Bihter , Toraman Suat
Published: August 2024

Alzheimer's disease (AD) poses a significant challenge in the realm of neurodegenerative disorders, necessitating effective therapeutic interventions. One promising approach involves the discovery of β-secretase 1 (BACE-1) inhibitors, pivotal in mitigating amyloid-β peptide accumulation, a hallmark of AD pathology. In this study, we compare the performance of three prominent machine learning methods, namely Gradient Boosting Machine (GBM), Random Forest (RF), and Support Vector Machine (SVM) in the discovery of BACE-1 inhibitors. Leveraging the BACE dataset sourced from MoleculeNet, comprising quantitative and qualitative binding results of compounds, we explored the classification efficacy of these methods. Our experimental results reveal distinct precision, recall, and accuracy metrics for each method, showcasing RF with precision and accuracy scores of 1.00 and 99.67%, respectively, followed by GBM and SVM. Furthermore, feature importance analysis underscores pIC50 as the most influential attribute across all methods, emphasizing its pivotal role in classifying BACE-1 inhibitors. Additionally, RF prioritizes Estate as the second most important feature, while AlogP emerges as GBM's secondary significant attribute. These findings shed light on the efficacy of machine learning techniques in identifying potential therapeutics for AD, offering insights into feature importance variations among methods and highlighting the significance of diverse molecular descriptors in drug discovery.
O PROFESSOR DO FUTURO: COMPETÊNCIAS TECNOLÓGICAS NECESSÁRIAS PARA O ENSINO NA ERA DIGITAL
Authors: Lopes Gabriel César Dias , Rodrigues Michele Aparecida Cerqueira , Catapan Márcio Fontana , Catapan Anderson , Guedes Gisele
Published: August 2024

Introdução: Este estudo explora as competências tecnológicas fundamentais que os professores devem adquirir para responder às exigências da era digital, considerando as profundas mudanças que a tecnologia tem ocasionado na educação. Assim, destaca-se a importância da adaptação dos docentes às práticas pedagógicas emergentes em função do progresso tecnológico, destacando o papel multifacetado e estratégico do professor no processo de ensino-aprendizagem. Objetivo: Investigar quais competências tecnológicas são necessárias para que os professores possam efetivamente utilizar as tecnologias e recursos digitais disponíveis, assegurando uma educação de qualidade na era digital. Método: Utilizou-se pesquisa bibliográfica, com abordagem qualitativa, por meio de revisão de literatura narrativa sobre a integração das tecnologias no ensino, as mudanças no perfil dos alunos e o perfil requerido do professor. Resultados: Aponta-se para a necessidade urgente de repensar o processo de formação dos professores, para que estes estejam alinhados com as demandas de um mundo digital em constante evolução. Os professores precisam ser capacitados para utilizar tecnologias de forma significativa, promovendo o engajamento dos alunos e estimulando o pensamento crítico, a criatividade e a colaboração. Conclusões: Portanto, conclui-se que, para garantir uma educação eficaz e de qualidade na era digital, é fundamental que os professores desenvolvam as competências tecnológicas necessárias. Isso permitirá que eles desempenhem seu papel de maneira mais eficaz, preparando os estudantes para os desafios do século XXI.
Analisa DPSIR Pembangunan Tol Semarang – Demak dan Kawasan Ekosistem Mangrove di Wilayah Pesisir Semarang – Demak
Authors: Solahudin Desty Stephany , Satria Bagiar Adla , Jannah Nabila Tsarwatul , Ilhamsyah Ilhamsyah
Published: August 2024

Proyek Jalan Tol Semarang – Demak merupakan merupakan salah satu Proyek Strategis Nasional (PSN) yang berada di Provinsi Jawa Tengah yang diharapkah dapat mendukung peningkatan konektivitas antar wilayah. Pembangunan yang direncanakan berada pada kawasan ekosistem mangrove yang dimungkinkan dapat menimbulkan dampak lingkungan. Dengan menggunakan pendekatan metode analisis kerangka DPSIR (Driving Forces-Pressures-State-Impacts-Responses), penelitian ini mengidentifikasi fenomena permasalahan yang terjadi akibat pembangunan tol melalui sudut pandang dinamika tata kelola lingkungan yang terjadi. Selain itu, penelitian ini menyoroti upaya rehabilitasi kawasan pesisir yang dilakukan oleh berbagai elemen masyarakat untuk melindungi lingkungan, namun terancam oleh proyek pembangunan tol. Perubahan kesadaran terhadap pentingnya ekosistem mangrove juga dibahas, dengan penekanan pada nilai ekologis, sosial, dan ekonomi yang harus dipertimbangkan dalam pengelolaan ekosistem mangrove. Di samping itu, terdapat adaptasi fisiologis dan morfologi tanaman mangrove serta peraturan yang dikeluarkan pemerintah untuk mengelola ekosistem mangrove dengan nilai penting ekologi, sosial, dan ekonomi.
Pengaruh Social Media Influencer dan Brand Image Terhadap Visit Intention Dimediasi oleh Customer Trust pada Skaer.Clinic
Authors: Adinda Fala Hindun , Pramono Rudy
Published: August 2024

Penelitian ini bertujuan mengeksplorasi mediasi Customer trust terhadap pengaruh Influencer Media Sosial dan Brand image pada Visit intention di Skaer.Clinic. Hasilnya menunjukkan bahwa Social Media Influencer dan Brand image memiliki pengaruh positif dan signifikan terhadap Visit intention, serta keduanya memengaruhi Customer trust. Namun, mediasi Customer trust pada pengaruh Social Media Influencer terhadap Visit intention ditolak. Skaer.Clinic disarankan untuk memperkuat kerja sama dengan influencer yang sesuai, meningkatkan citra merek, dan memelihara kepercayaan konsumen. Penelitian mendepankan perluasan sampel, pengukuran mediasi yang lebih mendalam, dan analisis demografi untuk pemahaman lebih baik tentang faktor Visit intention di konteks klinik kecantikan.
Room Reservation Integration Design to Simplifies Learning Process in University
Authors: Triswinadi Made Widiadnyani , Hediyanto Umar Yunan Kurnia Septo , Firdaus Taufiq Maulana
Published: August 2024

This research highlights the challenges that developing countries face managing room reservations within institutions. Nigeria and the Philippines lack transparency and real-time information, leading to confusion and inefficiency. Pakistan, the absence of an online system hinders access and raises data security concerns. Indonesia, the manual reservation process wastes time and creates uncertainty. The purpose of this research emphasizes the need for an online room reservation system to address issues such as transparency, real- time information, and efficiency. This research explores and Enterprise Resource Planning (ERP) system as a potential solution. Odoo Quickstart methodology was used to design and implement this solution. The Quickstart was chosen due to its affordability, flexibility and ease of modification. Odoo was chosen for its flexibility and configurability, allowing it to be customized and combined to meet the needs. The rental module in Odoo supports room reservation requirements by providing reservation form, schedule, delivery, and return functions in a single interface. Overall, the results of this study advocate for implementing an online room reservation system to improve the reservation process within educational institutions in developing countries.
Analisis Pelaksanaan Praktikum IPA Biologi Kelas VIII Semester I Selama Masa Pandemi di SMP Negeri Se-Kecamatan Sumpur Kudus
Authors: Hayati Wardah , Irdawati Irdawati , Razak Abdul
Published: August 2024

Penelitian ini bertujuan untuk menganalisis pelaksanaan praktikum yang dilaksanakan di sekolah dan kendala yang dihadapi dalam membantu peserta didik untuk melakukan kegiatan praktikum IPA Biologi selama masa pandemi di kelas VIII Sekolah Menengah Pertama Negeri se-Kecamatan Sumpur Kudus. Penelitian ini merupakan penelitian deskriptif dimana baik kualitatif maupun pendekatan kuantitatif digunakan sebagai teknik pengumpulan data. Studi ini dilakukan di kelas VIII SMP di Sijunjung, Sumpur Kudus pada semester pertama dari 2021/2022. Data dan sumber data dalam penelitian ini diambil dari perencanaan praktikum, pelaksanaan praktikum, evaluasi praktikum, dan permasalahan kegiatan praktikum Biologi. Data tentang perencanaan diambil dari rencana pelaksanaan pembelajaran (RPP), penilaian skor dan data catatan lapangan. Untuk pelaksanaan praktikum data diambil dari observasi terhadap kinerja guru, aktivitas guru dan aktivitas peserta didik serta catatan lapangan. Evaluasi praktikum dilakukan dengan melakukan wawancara kepada guru dan dari beberapa peserta didik. Selain itu, data tentang kendala yang dihadapi guru dan peserta didik berasal dari angket dan wawancara. Hasil studi menunjukkan bahwa rencana praktis cukup kompatibilitas dengan kurikulum yang tersedia. Dalam pelaksanaannya, ditemukan bahwa pelaksanaan praktikum masuk dalam indikator sedang. Selain itu juga terdapat beberapa kendala dalam pelaksanaan praktikum kegiatan. Beberapa di antaranya adalah manajemen alokasi waktu, kontrol guru, dan ketidaklengkapan alat dan bahan praktikum.
Analisa Struktur Box Underpass Jalan Danau Bogor Raya (Katulampa – Kecamatan Bogor Timur) Kota Bogor
Authors: Budiono Budiono
Published: August 2024

Pengembangan ibu kota baru Kota Bogor akan berada lokasi Kelurahan Katulampa Kecamatan Bogor Timur, untuk menuju ke lokasi pusat pemerintahan baru perlu akses ada jalan menuju kantor pemerintahan baru. Akses jalan ini  melewati kawasan Bogor Raya terus kejalan menuju kantor pemerintahan baru, akses jalan ini akan tersambung oleh adanya underpass. Perencanaan box underpass bertujuan untuk merancang box underpass dan merancang beban jacking yang digunakan pada proses pemasangan box underpass. Metode yang digunakan dalam merancang box underpass ini adalah metode LRFD (Load Resistance Factor Design). Box underpass dirancang dengan tebal pelat dinding 75 cm untuk pelat lantai bawah sebagai lantai pondasi tebal 100 cm. Bahan yang digunakan adalah beton mutu K-350 dan baja tulangan dengan mutu BjTD 40. Pembebanan yang bekerja pada box underpass, meliputi beban mati, beban hidup dan beban gempa. Tahap berikutnya menganalisis struktur underpass dilakukan dengan menggunakan SAP2000 untuk mendaptkan gaya dalam. Gaya dalam yang didapat digunakan untuk menghitung penulangan dan kontrol serviceability. Pada pelat lantai atas, tulangan pokok yang digunakan adalah D32 — 200, sedangkan tulangan bagi yang digunakan adalah D22 —200, Pada pelat lantai pondasi, tulangan pokok yang digunakan adalah D25 — 175, sedangkan tulangan bagi yang digunakan adalah D22 — 200. Pada pelat dinding, tulangan pokok yang digunakan adalah D32 — 200, tulangan bagi yang digunakan adalah D25 — 200, sedangkan tulangan geser yang digunakan adalah D16 — 400.
USING NURSERY RHYMES AS ENGLISH TEACHING MEDIA FOR YOUNG LEARNERS
Authors: Husni Na'imatul , Orenzah Della Teresia
Published: August 2024

In the learning process, teachers must be able to adapt to the goals, so appropriate supporting factors are needed to achieve these goals, one of which is the use of appropriate teaching media. Songs can be used as an intermediary in learning. Songs have a lot of content in them, for example regarding the content of song lyrics which can be included as learning material. Songs have a high level when it comes to language. The focus of this thesis research is 1) How to plan English learning using nurery rhymes as media? 2) How is English learning carried out using nursery rhymes as media? To identify these problems, this research uses a qualitative descriptive approach. This research uses a case study type. Determining informants using purposive sampling. Data collection techniques use observation, interviews and documentation. The data analysis in this research goes through stages, namely: data collection, data condensation, data presentation and drawing conclusions. Validity of data using triangulation of sources and techniques.
METHODS OF TEACHING READING COMPREHENSION FOR ESL AT MTS FAJAR SIDDIQ
Authors: Novianty Melisa , Fadly Muhammad Fahmi
Published: August 2024

Reading is one way to enable students and teachers to broaden their horizons in thinking and behaving. The more you read, the better you will be in all your actions in daily life.  In this case, the writer gives information for some methods of teaching reading comprehension for English Second Languagu (ESL). Therefore, the teachers can use the methods when they teach about reading. Hopefully, these methods will not only make the studensts but also Eglish teachers enthusiastic in learning reading comprehension. Besides, this ESL focus to junior high school students. The teachers of English teach reading by giving some methods in learning process. Moreover, the writer gave questionnaire for the students to know about the condition in their class. The result of questionnaire showed that 52.9 % students like to study and 52.9% like to read English. Therefore, in this case, the teacher of English should give high motivation and introduce the method of learning English, especially Readiing comprehension achievement. In order, the students will love to read in English more.
A Phenomenon of Anxiety as an Effect of Reading Literacy in English of Indonesia Learners’ Context
Authors: Zananda Tiray Febria
Published: August 2024

Anxiety, an unpleasant state of inner turmoil and apprehension, often accompanied by nervous behavior, has proved that effects on the reading English literacy of Indonesia foreign learners’ context. The anxious feeling gives negative attitudes toward reading since each single thing is easy to comprehend by involving emotional. In order to reduce the anxious feeling, reading atmosphere is important to be implemented in order to help the learners’ literacy in English increase. It is not only that providing materials that cope the familiar local culture in English language materials help students become aware of how their local cultures enriches their linguistic resources and social practices, thereby making their language learning meaningful.
The Use of Picture Series in Writing Skill
Authors: Agustiawati Hartini
Published: August 2024

Teaching English is a challenging to teacher of English. They must work hard to teach, introduce and persuade students to learn. There are four skills in teaching English, such as listening, speaking, reading and writing. Among them, speaking will be challenging for students. They are afraid to talk and no self confidence to write in English. It is totally hard for students who learn English as a Foreign Language. They don’t have more opportunities to learnt English.  It makes students lazy to learn, speak and write English. In this case, teachers must be smart to find strategy or right technique.  In order to improve students’ interest and ability a method can be used.  Picture Series is one of the methods which is suitable to be applied in teaching students in the classroom. This method can motivate and inspire students to write. Students will find ideas through the pictures. It is so helpful and useful in order to improve students’ writing ability.
Revisão da Literatura Sobre os Principais Anestésicos Utilizados na Eletroconvulsoterapia
Authors: Seif Eddine Livia , Brandão Carneiro Luisa , Rodrigues Lorencini Nayad , Da Motta Sarlo Antonio Luisa , Passini Secchin Lina , Bumachar Maria Antônia , Oliveira Sampaio Neves Isadora , Ferreira Rodrigues João Vitor , De Castro Japiassú Leandro
Published: August 2024

Este artigo revisa a literatura sobre o uso de anestésicos na eletroconvulsoterapia (ECT), comparando cetamina, propofol, etomidato, remifentanil, metohexital e tiopental. O objetivo é avaliar como diferentes anestésicos impactam a eficácia e segurança da ECT. Para isso, foi realizada uma revisão de estudos publicados entre 2014 e 2024, selecionados através de buscas nas bases de dados PubMed e na Revista da Sociedade Portuguesa de Anestesiologia. A pesquisa focou em meta-análises, revisões sistemáticas e ensaios clínicos randomizados. Conclui-se que a escolha do anestésico deve ser individualizada, levando em conta os efeitos colaterais e a experiência da equipe médica. Apesar dos avanços na anestesia, não há evidências definitivas sobre a superioridade de um anestésico em relação aos outros, e a literatura sugere que a duração das crises convulsivas não está diretamente correlacionada com melhores desfechos clínicos.
Manejo da Hipertensão Arterial em Pacientes com Doença Renal Crônica
Authors: De Araújo Amorim Filho Rodrigo , Artur Costa Cruz  , Gabriella Sousa Almeida  , Thalita Martins Bezerra  , Leonardo Cortes de Aguiar Franco  , Victoria Menezes Cordeiro  , Gilberto de Souza Brito Filho  , Amanda Machado Kramel  , Carolina Kertelt Legnani  , Gabriel Ferreira Lima  , Raimundo Nogueira de Oliveira Júnior  , Jaqueline Giselle Farias Fernandes  , Thassio Renan Nascimento Lucena  , Bárbara Rezende Teixeira  , Luciana Ferreira dos Santos
Published: August 2024

A hipertensão arterial (HA) é uma condição comum em pacientes com doença renal crônica (DRC), impactando significativamente o prognóstico e a qualidade de vida desses indivíduos. O objetivo deste estudo foi analisar as intervenções e estratégias de manejo da hipertensão em pacientes com DRC, avaliando a eficácia e as abordagens terapêuticas recentes. Foi realizada uma revisão integrativa utilizando as bases de dados Scientific Electronic Library Online (SCIELO) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), com descritores em ciências da saúde como “hipertensão arterial”, “doença renal crônica” e “manejo da hipertensão”. Os resultados mostram a importância de estratégias de tratamento personalizadas e a necessidade de intervenções contínuas para controle efetivo da hipertensão em pacientes com DRC. A conclusão ressalta a importância de protocolos ajustados e a integração de múltiplas abordagens terapêuticas para otimizar os resultados clínicos.
Benefícios da Linfadenectomia Estendida no Tratamento do Câncer Gástrico: Um Artigo de Revisão
Authors: Sversuti filho Marco antonio , Gustavo Henrique Pedroso  , José Pedro Figueiredo Lima  , Isabella Zaina Ferrari Naufal  , Gabriela Schlabendorff  , Isadora de Almeida Ramos Amorim  , Lara Cristina Silva Inácio  , Samer Majid Ghadie  , Anne Carolina Xavier Medeiros  , Matheus Pereira Costa  , Rachel Carvalho Lemos  , Gabriel de Paula Almeida  , Allan Oliva Filho
Published: August 2024

Objetivos: Avaliar a eficácia clínica e a segurança da linfadenectomia estendida (D2 e D3) no tratamento cirúrgico do câncer gástrico, comparando essas abordagens com a linfadenectomia padrão (D1) em termos de sobrevida geral, controle da doença e complicações pós-operatórias.
Métodos: Foi realizada uma revisão da literatura utilizando PubMed e Google Scholar, abrangendo publicações de 2004 a 2024. Os critérios de inclusão compreenderam ensaios clínicos randomizados, estudos observacionais, revisões sistemáticas e metanálises que avaliaram o impacto da linfadenectomia D2 e D3 em pacientes com câncer gástrico. Os principais desfechos de interesse foram sobrevida geral, complicações pós-operatórias, recorrência da doença e qualidade de vida.
Resultados: A linfadenectomia D2 demonstrou taxas de sobrevida geral superiores em comparação com a D1, com melhorias significativas observadas tanto nos desfechos de curto quanto de longo prazo. No entanto, os resultados para a linfadenectomia D3 foram heterogêneos; embora alguns estudos indicassem benefícios para subgrupos específicos de pacientes, apresentam uma maior incidência de complicações pós-operatórias.
Conclusão: A linfadenectomia D2 deve ser considerada a abordagem cirúrgica padrão para o câncer gástrico quando operável, dado seu equilíbrio favorável entre eficácia e segurança. Embora a linfadenectomia D3 possa oferecer vantagens potenciais em casos selecionados, mais pesquisas são necessárias para validar seus benefícios e estabelecer diretrizes clínicas precisas. As decisões sobre o uso de linfadenectomias mais extensas devem ser individualizadas, levando em consideração os riscos e benefícios específicos para cada paciente.
 
Palavras-chave: Câncer gástrico, linfadenectomia estendida, linfadenectomia D2 e D3, beneficio e resultados.
Resistência antimicrobiana de Klebsiella spp isolada em recém-nascidos internados no serviço de neonatologia.
Authors: Cardona Tamayo Yuriasne , Rojas Borrero Alexander
Published: August 2024

RESUMO:
Os processos infecciosos em todo o seu espectro clínico são causa frequente de internamentos hospitalares e responsáveis ​​por taxas variáveis ​​de morbilidade e mortalidade. A resistência aos antimicrobianos é um problema crescente que não pode ser perdido de vista, para o qual não há registo a nível local e sem o qual não existe; uma dúvida condiciona o tratamento. Pretende-se realizar um estudo prospectivo, longitudinal e descritivo, com o objetivo de determinar a resistência antimicrobiana de Klebsiella spp isolada em recém-nascidos internados no serviço de Neonatologia do Hospital Geral Universitário Dr. “Agostinho Neto” de Guantánamo, durante o período de setembro de 2022. a maio de 2023. Recomenda-se o desenho de novas pesquisas que permitam estabelecer fatores de risco para infecções por germes resistentes, tanto na comunidade como no ambiente hospitalar.
Membranas de celulose bacteriana e nanopartículas de prata para aplicações em tratamento de feridas e queimaduras
Authors: Garcia Rabelo Letícia , Machado de Abreu Danilo José , De Oliveira Magno Carlos Henrique , Chaves Vieira Laryssa , Hilsdorf Piccoli Roberta , Elvis de Oliveira Juliano
Published: August 2024

Introdução: As queimaduras são consideradas um grande desafio médico-social no Brasil e no mundo, envolvendo elevada incidência e morbimortalidade. Uma das principais complicações relacionam-se à infecção secundária destas lesões. Dessa forma, curativos com ação antimicrobiana são aliados ao tratamento dessa condição, favorecendo a cicatrização. A inserção do uso tópico da prata no tratamento de queimaduras foi um marco na redução de morbimortalidade. As membranas de celulose bacteriana se destacam na área da saúde pela sua biocompatibilidade e facilidade em incorporação de componentes. Este trabalho desenvolveu membranas de celulose bacteriana, impregnadas com nanopartículas de prata, e testou sua ação antimicrobiana contra principais patógenos colonizadores de feridas e queimaduras. Método: Foram produzidas membranas de celulose bacteriana em meio de cultivo sintético. As membranas passaram por diversos processos de lavagem, purificação, descelularização, secas em temperatura ambiente e impregnadas em nanopartículas de prata. Foi realizado teste de sensibilidade das membranas contra Staphylococcus aureus ATCC 23925 (Gram positivo) e Pseudomonas aeruginosa ATCC (Gram negativo), bactérias comuns em infecções secundárias de queimaduras, utilizando Cloranfenicol como controle. O teste avaliou o halo de inibição médio (HIM) em milímetros (mm) Resultados:. Contra S. Aureus o HIM do controle foi 17,2 ± 3,45mm; já das membranas o HIM foi 7,25 ± 0,1mm. Contra P. aeruginosa o controle obteve HIM de 32,88 ± 0,91mm; e as membranas de celulose bacteriana HIM de 8,91 ± 0,69mm. Conclusão: As membranas desenvolvidas possuem atividade antimicrobiana contra S. aureus de 42,12% e 27% contra P. aeruginosa quando comparada ao controle (Cloranfenicol), sendo uma ação inibitória significativa contra os patógenos analisados. Para sua aplicação prática futura, mais estudos sobre suas propriedades devem ser realizados.
Security and Efficiency of Quantum Key Distribution Protocols: A Comprehensive Review
Authors: Grover Saanvi
Published: August 2024

Quantum Key Distribution (QKD) protocols offer a revolutionary approach to secure communication, leveraging the principles of quantum mechanics to enable theoretically unbreakable encryption. This comprehensive review examines the security and efficiency of various QKD protocols, including BB84, E91, and Continuous Variable QKD. We analyze the fundamental principles underpinning these protocols, their implementation challenges, and the practical considerations for real-world deployment. Special emphasis is placed on the security proofs of QKD, addressing potential vulnerabilities such as photon number splitting attacks and detector blinding attacks. Additionally, we explore the efficiency of QKD systems in terms of key generation rates, distance limitations, and integration with existing communication infrastructures. Recent advancements in QKD technology, including satellite-based QKD and quantum repeaters, are also discussed. Our findings highlight the critical role of QKD in future-proofing communication security and the ongoing efforts to enhance its practicality and scalability. This review aims to provide a detailed understanding of the current state of QKD protocols, offering insights into their potential to transform secure communications in the quantum era.
WOMEN ENTREPRENEURIAL DEVELOPMENT: A CASE STUDY OF WOMEN SELF-HELP GROUPS ENTREPRENEURS
Authors: Vidya Kishan Alva  , Dr.Kusum Thantry
Published: August 2024

Women entrepreneurs in SHGs play a vital role in driving economic and social change. Their endeavors not only enhance their own lives but also contribute significantly to the well-being of their families and communities. This research paper delves into the transformative journey of women entrepreneurs within self-help groups (SHGs) and examines their profound impact on community development and economic growth. Through a meticulous analysis of secondary sources, including scholarly articles, government publications, and authentic websites, the study investigates the status, motivations, challenges, and achievements of women entrepreneurs in SHGs.The findings underscore the pivotal role of SHGs in empowering women entrepreneurs by providing microloans, training programs, and access to markets. These initiatives enable women to establish businesses, invest in various sectors, and support their families. Motivated by financial independence, community development, and personal growth, women entrepreneurs within SHGs navigate challenges such as societal norms, limited access to technology, and legal barriers. By addressing the challenges they face and providing tailored support, societies can harness the full potential of women entrepreneurs, fostering inclusive economic development and social progress.
KEYWORDS: Women Entrepreneurs, Self-Help Groups (SHGs), Women's empowerment, Community development, Economic growth, Financial independence, Microloans, Training programs
Impact of information technologies on the economic security of enterprises
Authors: Terpylo Dmytro
Published: August 2024

It is noted that the revival of the economy can only be carried out by supporting the development of business entities since they are the engine that ensures the stability of economic and social phenomena. In the conditions of the formation of the information society, the goal of this article is not just relevant but urgent - the study of directions for strengthening the informational component of economic security, which should be a priority for every enterprise. Organizations conduct their activities in conditions of rapid digitization, where technologies that will determine the future development of business play a crucial role in many innovative processes: large data sets, cloud platforms, solutions based on artificial intelligence and the Internet of Things, cryptocurrencies, augmented reality and robotics of business processes. All this will contribute to increasing the profitability of companies by directly saving costs and time for conducting economic activities, reducing the number of necessary intermediaries and employees, and reducing the human factor's influence on the organization's functioning. It was determined that the modern approach to understanding economic stability (economic security) is one-sided, as it is limited to the framework of financial categories. By the concept of "sustainability" in the economic literature, most scientists and practitioners understand the system's ability to achieve its goal, considering the change of internal and external factors, which leads, as a rule, to improving its structural and functional content. It is substantiated that modern information systems and technologies are not just tools, but powerful catalysts for increasing the productivity and efficiency of employees. Objects of information and means of their provision are becoming more and more significant, because of which information security of organizations comes to the fore. Increasing volumes of information, as well as the processing, transfer, creation, and storage of databases, are widely demanded services at present. Every day, in the process of management, enterprises are increasingly immersed in the information environment, reporting and information are stored electronically, local and global networks are used. All this creates and increases threats to confidential information.
Keywords: economic security, information society, digitalization, innovation processes.
Needs Analysis in English for Moroccan Applied Mathematics Graduate Students at Ibn Zohr University
Authors: Khalil Abdelmomen , Elfatihi Mohamed , Hellalet Nadia
Published: August 2024

This study examined the English academic needs of students in the Applied Mathematics in the Science of Engineering (AMSE) master program at the Faculty of Sciences, Ibn Zohr University, Morocco. It aimed at determining the gap between students' language needs and their actual competencies and identifying learners’ perceptions of their linguistic needs and their linguistic difficulties. The study was conducted based on a mixed-methods design approach with multiple data collection instruments. As a research framework, the Dudley-Evans and St John's (1998) needs analysis model was used. The results showed that participants attach different values to the importance and competence of macro- and micro-language skills. Students and teachers placed a high value on grammatical knowledge. Students valued grammar, speaking, and writing highly, while subject matter teachers valued grammar, speaking, and writing highly, but listening and pronunciation skills were valued as less important. The study showed that learners' English proficiency level is average. Their average English levels then influenced their academic achievement. Based on the aforementioned results, the researchers proposed that syllabus designers should address the macro- and micro-skills regarding academic studies when developing and redesigning course syllabus and its objectives in the ESP context.
Creating a Happy and Sustainable Society: A Case Study of an NGO ‘Pehchaan
Authors: - Aparna Mohan , - Mala Tandon , - Monika Gautam
Published: August 2024

A community that lasts and includes everyone can only be created by ensuring that everyone, especially the underprivileged children, feels pleased and supported. During the difficult COVID-19 times, the Pehchaan NGO, run by Mr. Ratnesh Mathur and his staff in Lucknow, has been a ray of hope. They have been working nonstop to provide impoverished kids with the education, healthcare, and support they require to flourish.
Lucknow -based NGO - Pehchaan has been actively involved in a number of community service projects since its establishment in October 2019 and official registration in August 2021. These projects range from relief efforts for COVID-19 to educational endeavors in rural areas including Etawah, Auraiya, Lucknow, and Allahabad. The group responded to the epidemic quickly and thoroughly, offering vital assistance including food distribution, migrant transportation, and flood relief operations.
Pehchaan’s all-encompassing strategy also addresses long-term issues including environmental sustainability, economic empowerment, and education promotion in addition to providing short-term assistance. In addition to helping underprivileged kids, its awareness efforts, donation drives, and adoption programs have promoted a sense of civic duty and responsibility.
Pehchaan’s work has a lasting effect on a variety of fields, including youth participation, environmental conservation, healthcare, and education. Their endeavors are an expression of their dedication to community service and progress, encapsulating the values of empathy, agency, and longevity.
Antioxidant Activity and Nutrient Analysis of Benincasa Hispida (Ash Gourd) Leaves, Pulp and Seeds: A Comparative Study
Authors: - ANIL B , - Nithya Kakkera
Published: August 2024

Ash gourd, scientifically termed Benincasa hispida and commonly known as Kushmanda is a green vegetable. It has been well-regarded for its significant medicinal values since ancient times and is widely documented in Ayurvedic texts. This study investigates the antioxidant, nutritional, and mineral properties of different parts of the Ash gourd (Benincasa hispida), including leaves, pulp, and seeds, to evaluate their potential health benefits. the Ash gourd components were subjected to various analytical methods including DPPH, FRAP, and ABTS assays for antioxidant activity, and biochemical techniques for vitamin C, fiber, protein, carbohydrate, fat, ash, moisture content, and mineral estimation. Results demonstrated that Ash gourd seeds exhibit the highest antioxidant activity and nutrient content, including carbohydrates, proteins, and fats, compared to the leaves and pulp. The leaves were found to have the highest calcium content, while the seeds showed significant potassium and iron levels. Comparative analysis with pumpkin samples revealed that Ash gourd has higher carbohydrate and fiber content, whereas pumpkin seeds are richer in proteins, fats, and iron. The findings revealed the nutritional and medicinal value of Ash gourd, supporting its use in dietary and therapeutic applications. Biochemical activity of the fruit and other parts of the plant includes anti-oxidative, anti-inflammatory, anti-angiogenic, de-toxicant, and curative effects in treating various ailments.
Evaluation of Construction Support by the Government through Business Entities on the Trans Sumatra Toll Road (Case Study: Terbanggi Besar – Kayu Agung Toll Road Section)
Authors: - Hera C. Putri , - Iris Mahani , - Budi Hasiholan
Published: August 2024

Terbanggi Besar – Pematang Panggang – Kayu Agung toll road is part of the Trans Sumatra Toll Road that received 83 km of construction support carried out by the Toll Road Business Entity that won the auction of toll road projects on the island of Java with a high rate of return on investment. Generally, construction support is provided directly by the government, but in this case the government provides construction support through other toll road business entities. The provision of construction support through toll road business entities on the Terbanggi Besar – Pematang Panggang – Kayu Agung Toll Road has financially increased the investment feasibility parameters, including: an increase in the IRR value to 12% from the original 9.36% before the provision of construction support; The NPV value with the provision of construction support has a better NPV value, which is Rp. 3,875 T compared to the NPV value without construction support of - Rp. 2,044 T; The value of the payback period without the provision of construction support is for 22 years and 3 months and with the provision of construction support for 19 years and 5 months. However, in the implementation process, the quality of toll road infrastructure at construction support locations is not met, resulting in business entities still having to participate in bearing quality risks to construction work carried out by the government. Business entities receiving construction support must bear maintenance costs due to repairs to damage to the construction support site. However, the increase in maintenance costs in general did not have a significant effect on the investment feasibility parameters of the Terbanggi Besar – Pematang Panggang – Kayu Agung toll road project. The increase in maintenance costs had an effect on the decrease in IRR by 1.4%. The NPV indicator also decreased by Rp. 198 billion or worth 5.1%. The payback period has also increased from 19 years and 5 months to 19 years and 8 months. However, the mechanism for providing construction support through business entities needs to be considered to ensure that the benefits of providing construction support can be felt to the maximum.
Energy Efficiency in IoT Devices: Challenges, Techniques, and Future Directions
Authors: - Navya Sinha
Published: August 2024

This paper explores the challenges associated with energy consumption in IoT devices, reviews current techniques employed to enhance energy efficiency, and suggests future directions for research
Cross-Sectional Study on the Influence of iPad or Tablet Usage on Student Engagement, Learning Outcomes, and Attitudes Toward Technology among University of Cyberjaya Students
Authors: - Sarani Letchumanan , - Kirttena Loganathen , - Haifa Hannah Binti Hazemi , - Danish Shahin Bin Sirat , - Lei Lei Win
Published: August 2024

This study assessed the impact of iPad and tablet-based activities on students' attitudes towards technology, engagement levels, and perceived learning outcomes at the University of Cyberjaya, examining the relationship between the frequency of iPad use and these educational metrics. A cross-sectional study was done among 369 undergraduate students using iPads or tablets at the University of Cyberjaya from 2023 to 2024 collected data via online questionnaires on demographics, feelings about technology, performance expectations, perceived learning, and engagement. Statistical analyses, including descriptive statistics and regression analysis, were used to analyze the data. Most respondents were female (63.4%), Malay (40.9%), MBBS students (54.5%), with high frequencies of daily technology use (61.5%) and in-class tablet use (51.2%) reported. Significant percentages indicated positive feelings about technology (86.7%), high performance expectations (80.5%), perceived learning benefits (82.7%), and effectiveness in meeting course objectives (88.6%). Regression analysis confirmed significant but weak correlations between iPad use and attitudes towards technology, perceived learning, and engagement. The study underscores the positive impact of iPads on students' educational experiences, highlighting their role in enhancing engagement, learning outcomes, and attitudes towards technology, though the impact on aca-demic performance may still be influenced by other factors.
An Overview of Patient Safety Supervision in Government Hospitals
Authors: - Apriando Rahmadani , - Yulastri Arif , - Rian Ferdian
Published: August 2024

Background: Effective supervision is needed to achieve optimal implementation of patient safety goals, where patient safety is prioritized in every activity. Nurses' performance in implementing patient safety goals is influenced by several factors.
Objective: To know the description of patient safety supervision in hospitals in 2024.
Method: This study is a quantitative study with a cross-sectional design conducted in April-June 2024 at the Hospital. The study population was all executive nurses in the hospital inpatient room. The population was 42 people with total sampling technique. The research instrument used a questionnaire to collect data on the characteristics of respondents consisting of nurse identity, namely: level of education, length of work, and supervision.
Results: Patient safety supervision is mostly in the good category (78.57%).
Conclusions: Patient safety supervision in hospitals in 2024 is mostly in the good category. This indicates that nurses have implemented various safety standards and effective procedures to protect patients from injury or harm during treatment.
On the Solvent-mediated Stabilization of Phenol-formaldehyde Resole Resin- A Revisit
Authors: - C.P.Reghunadhan Nair , - Aswini Narayanan , - Temina Mary Robert
Published: August 2024

The aging of phenol formaldehyde resole (PF) resin was monitored from an increase in viscosity, indirectly measured from its flow time though a capillary. A way to arrest the self-condensation reaction responsible for aging, is addition of a solvent so as to retards the kinetics of the crosslinking reaction. Conventionally, ethanol was used and is still preferred as the diluent for PF resin. However, no rationale has been given for this preference. On re-investigation, we too found that alcohols are the best diluents to arrest or retard aging of resoles. A detailed study of the evolution of viscosity with time for different alcoholic solution, concentrations and temperatures vis-à-vis a reference solvent, Methyl, Ethyl Ketone (MEK) led to the conclusion that alcohol causes stabilisation of P-F resins by (i) sharing of the non-bonding electrons on the oxygen of alcohols with the electrophilic carbon of the H2C-OH groups of methylol, which quenches the latter’s reactivity towards another methylol phenol, (ii) the nucleophilicity of the OH group, (iii) the ease of proton transfer from the alcoholic -OH groups that facilitates the formation of benzyl alkyl ether with reduced reactivity towards phenols. The efficacy of the alcohol depends mainly on its nucleophilicity and steric environment. For these reasons, the stabilising effect of the alcohols decreased in the order tertiary> primary > secondary. Though the tertiary alcohols are the best, they are expensive and has, in general, a noxious ordure. The next choice falls on a primary alcohol that is sterically least hindered and has adequate nucleophilicity Though methanol appeared to be a good choice, its high volatility and toxicity impede its preference. The next choice is ethanol which is comparatively a strong nucleophile, is less toxic and volatile, easily available, low priced and is also an excellent solvent for P-F resin. Thus, the choice of ethanol as a preferred stabilising solvent for P-F resin is scientifically rationalized..
Spring wetland flora inventory?Colorado National Monument survey report
Authors: McBride Wendy , Tacheeni Kesonie Dave , Thorn Emily , McBride Wendy , Tacheeni Kesonie Dave , Thorn Emily
Published: August 2024

This report provides the results from the 2021 spring wetland flora inventory at Colorado National Monument. In total, seven National Park Service units within the Northern Colorado Plateau Network determined the need to evaluate and map spring and wetland condition based on the presence/absence of perennial obligate and facultative wetland plant species known to occur in the parks. Mapping spring and wetland areas for each park provides a baseline measure of areas sensitive to drying that can be used to monitor change over time. The overall objective of the project was to establish a baseline for the area and condition of wetlands, seeps, and springs to provide supporting evidence for any future claims of impairment resulting from groundwater management actions.

Survey results at Colorado National Monument identified and inventoried springs and wetlands at 14 of 17 surveyed sites. This report summarizes the results at these 14 sites, including spring type identification, dominant herbaceous plant species present, average plant cover, wildlife sign frequency and observation, and wetland feature map figures.
Development Of Hiking Tourism Potential In Curug Cikawah, Ciasmara Village, Bogor District
Authors: Abidin Jenal , Yunus Farhan Rahadian , Christine Novia
Published: August 2024

This research discusses the development of hiking tourism potential at Curug Cikawah, Ciasmara Village, Bogor Regency. With the growing trend of special interest tourism, the development of hiking tourism in the area is expected to provide a variety of tourist attractions and have a positive impact on the economy of the local community. This research uses a qualitative descriptive approach with observation, interviews, documentation and SWOT analysis methods. The results of the SWOT analysis show strengths such as a beautiful atmosphere and local guides, weaknesses such as locations far from the crowds, opportunities such as sports tourism trends, and threats that need to be anticipated. The strategy for developing hiking tourism at Curug Cikawah was also prepared based on the results of the SWOT analysis. It is hoped that the development of hiking tourism can provide benefits for developers, local communities and tourists visiting the area.
PENYIMPANGAN PERILAKU REMAJA PRAKTEK KEPERAWATAN KOMUNITAS DI RT V RW X KELURAHAN KORONG GADANG WILAYAH KERJA PUSKESMAS KURANJI
Authors: Reni Ises , Nurleny  , Adha Dedi , Andika Mira , Efendi Zulham , Hamdayani Delvi , N. Rachmadanur  , Febriyanti  , Yolanda Yola , Ariyani Farida
Published: August 2024

Latar Belakang: Kenakalan remaja adalah tindak perbuatan yang dilakukan anak remaja dan perbuatan melawan hukum yang mana terdapat di dalamnya antisocial, antisusila serta melanggar norma agama, maka kalua dilanggar orang yang sudah menginjak dewasa akan menjadi tindak kejahatan. Beberapa hal yang harus selalu diingat dalam menghadapi remaja yaitu bahwa jiwa remaja adalah jiwa yang penuh gejolak dan lingkungan social juga di tandai dengan perubahan social yang cepat. Perilaku merokok adalah sesuatu yang dilakukan seseorang berupa membakar dan menghisapnya serta dapat menimbulkan asap yang dapat terisap oleh orang-orang disekitarnya. Masa remaja merupakan salah satu periode dari perkembangan manusia, masa ini meliputi perubahan biologi, perubahan psikologi dan perubahan social. Merokok sekarang ini sudah menjadi trend di kalangan pelajar laki-laki baik siswa SMP maupun SMA bahkan siswa SD pun sudah ada yang mencobanya. Ada beberapa siswa yang nekad melakukan merokok di sekolah sekalipun larangan merokok di sekolah.
Metode: Diperlukan edukasi mengenai penyimpangan perilaku remaja di RT V RW X Kelurahan Korong Gadang Wilayah Kerja Puskesmas Kuranji
Hasil: Terlihat peningkatan pengetahuan remaja tentang penyimpangan perilaku remaja
PENINGKATAN TATAKELOLA BUDIDAYA IKAN DENGAN PENERAPAN SISTEM SMART FISHERY
Authors: Rianto Rianto , Aradea Aradea , Mubarok Husni , Widiyasono Nur
Published: August 2024

Maju mundurnya suatu perusahaan atau organisasi salah satunya sangat bergantung kepada manajemen dari perusahaan atau organisasi itu sendiri. Manajemen atau pengelolaan dapat dimaknai sebagai pengelolaan sumber daya yang dimiliki yang digunakan sepenuhnya secara efektif untuk kemajuan perusahaan atau organisasi. Manajemen atau pengelolaan ini memiliki lima (5) unsur penting, yaitu 1) man, 2) money, 3) material, 4) machine, 5) method, dan 6) market. Pentingnya pengelolaan yang baik ini, bukan hanya untuk perusahaan atau organisasi yang besar, melainkan juga penting untuk skala usaha mikro, kecil dan menengah (UMKM), termasuk didalamnya UMKM yang bergerak dalam bidang perikanan seperti Karang Taruna Ikhlas Bakti Desa Mangunreja. Salah satu permasalahan yang dihadapi oleh Karang Taruna Ikhlas Bakti Desa Mangunreja adalah unsur machine dalam arti belum memanfaatkan secara maksimal teknologi pendukung untuk kegiatan operasional, khususnya penggunaan piranti lunak atau software pendukung pengelolaan usaha. Oleh karena itu, fokus utama pada pengabdian ini adalah untuk menerapkan alat dan piranti lunak Smart Fishery untuk mendukung kegiatan operasional di Karang Taruna Ikhlas Bakti Desa Mangunreja. Luaran yang menjadi target capaian program ini yaitu dimuat dalam Jurnal Nasional ber-ISSN, dimuat pada artikel media cetak/elektronik dan adanya video dokumentasi kegiatan yang dimuat pada media online dengan indikator capaian berupa pemahaman manajemen usaha dengan memaksimalkan penerapan IT berupa piranti lunak Smart Fishery.