bluuebunny/crossref_metadata_2025 huggingface dataset:
Badania przyczepności stwardniałych zaczynów cementowych do formacji skalnej po zastosowaniu różnych rodzajów płuczek wiertniczych i cieczy przemywających
Authors:   Oddział Geologii i Eksploatacji PGNiG w Warszawie, Orlen S.A., Łyczko Krzysztof , Wójtowicz Tomasz ,   Exalo Drilling S.A., Grupa Orlen, Rzepka Marcin ,   Instytut Nafty i Gazu - Państwowy Instytut Badawczy, Jasiński Bartłomiej ,   Instytut Nafty i Gazu - Państwowy Instytut Badawczy
Published: September 2024

W artykule omówiono zagadnienia dotyczące przyczepności stwardniałych zaczynów cementowych do pobranych z piaskowca rdzeni skalnych, na których wytwarzany był osad z różnych rodzajów płuczek wiertniczych. Rdzenie z wytworzonym osadem przemywano następnie cieczą przemywającą oraz buforem. Przemyte próbki zalewano zaczynem cementowym, pozostawiając je do związania na okres 2 i 7 dni. W trakcie badań wykorzystywano specjalne stanowisko przeznaczone do wytwarzania osadów i przemywania próbek skalnych. Następnie za pomocą maszyny wytrzymałościowej wyznaczano wartość przyczepności zaczynu cementowego do skały. W badaniach laboratoryjnych stosowano płuczkę z PHPA (polimerowo-potasową) oraz płuczkę glikolową. Używano odpowiednio dobranych cieczy przemywających oraz buforu. W badaniach wykorzystywano cztery rodzaje zaczynów cementowych. Były to zaczyny zawierające nanokomponenty (nano-SiO2 oraz nano-Al2O3), zaczyn z dodatkiem lateksu oraz zaczyn konwencjonalny bez specjalnych dodatków. Spośród przebadanych cieczy przemywających najlepsze połączenie na kontakcie stwardniały zaczyn cementowy–skała piaskowcowa uzyskano po zastosowaniu wodnego roztworu niejonowego surfaktantu z grupy etoksylowanych alkoholi tłuszczowych. Komponenty zaczynów cementowych w postaci nanododatków i lateksu powodują polepszenie parametrów technologicznych zaczynu cementowego (w tym zwiększenie przyczepności do skały). Nanotlenek glinu i krzemu oraz lateks redukują również m.in. odstój wody, czyli tzw. wolną wodę, z zaczynów oraz obniżają filtrację, co ma szczególne znaczenie w przypadku cementowania otworów kierunkowych. Zdecydowana większość badanych próbek cechowała się bardzo wysoką przyczepnością kamienia cementowego do skały. Można to tłumaczyć prawidłowym dobraniem cieczy przemywającej i cieczy buforowej do konkretnego rodzaju płuczki, a następnie użyciem odpowiedniego zaczynu cementowego. Opracowane w ostatnich latach w INiG – PIB ciecze przemywające oraz zaczyny cementowe mogą być wykorzystane w krajowym przemyśle wiertniczym, co powinno przyczynić się do poprawy jakości wiązania zaczynu cementowego z rurą okładzinową i formacją skalną.
Diagnosis of the formation damage process using the theory of catastrophe
Authors:   Azerbaijan State Oil and Industry University, Mammadov Ramil M. , Sultanova Arzu V. ,   Azerbaijan State Oil and Industry University
Published: September 2024

A broad area of interdisciplinary research, commonly referred to as nonlinear science, includes nonlinear thermodynamics, catastrophe theory, dynamic chaos theory, and fractal mathematics. This field has produced numerous influential figures, many books, and countless articles. Many popular books have been published on the theory of catastrophes, chaos, and fractals. Systems studied by nonlinear science are usually called complex; their properties are not reducible to those of their components and exhibit newly emerging, or “emergent” features. A catastrophe is an abrupt change that occurs as a sudden response of a system to a gradual change in external conditions. The mathematical description of phenomena associated with sharp and qualitative changes is provided by the theories of singularities and bifurcations. Bifurcations (catastrophes) are discontinuities in systems described by smooth (continuous) functions. This article attempts to make an adaptive operational decision aimed at preventing complications arising from sand production in wells, based on the application of catastrophe theory and mathematical and statistical tools. The influence of sand production on well productivity, particularly the associated plug formation, is a relevant issue and pertinent research focus today. The physical cause of the sand plug’s effect is that due to the small cross-section of the wellbore, the sand plug located above the productive horizon acts as a downhole fitting, creating significant resistance to the upward flow. Early diagnosis of the onset of near-wellbore zone damage and the transition of wells to sand-producing status is crucial. In addition, timely control of complications related to sand removal during the complete distortion of the bottomhole zone, when the sand production process is fully established, is of great relevance. The effectiveness of measures to prevent the complications in operation process depends on the validity and efficiency of such control.
Aritmética nas Escolas de Aprendizes Artífices (1909-1926): distanciamentos e aproximações entre o Amazonas e Santa Catarina
Authors: Barbaresco Cleber Schaefer , Rodriguês Jeremias Stein , Silva Neto Oscar , Costa David Antonio da
Published: September 2024

Este artigo se insere nas pesquisas de âmbito dos estudos sócio-históricos das Escolas de Aprendizes Artífices (EAAs) do Amazonas e Santa Catarina; instituições que fizeram parte da rede de ensino profissional criada em 1909, tendo como objetivo produzir um relato da trajetória do ensino da matemática nas referidas instituições, com o intuito de responder a seguinte questão: quais são as principais aproximações e distanciamentos relacionadas à trajetória da história do ensino dos saberes aritméticos nessas escolas? Apoiado nos conceitos de representação e apropriação de Chartier utilizam-se como fontes decretos e relatórios emitidos pelo Ministério da Agricultura, Indústria e Comércio (MAIC); órgão ao qual as escolas estavam subordinadas no período de 1909 a 1930. Identificaram-se convergências e dissonâncias entre as escolasno que tange à aplicação das prescrições estabelecidas, bem como da organização e propósito do ensino de aritmética, contribuindo-se com a compreensão de como se dava, na época, o ensino de Aritmética na formação profissional ofertada por essas instituições. Observaram-se propósitos diferentes para esse ensino, um voltado mais para a prática profissional, de modo a se caracterizar como saber rudimentar, e outro para a continuidade da formação escolar do estudante, na qual assume a perspectiva de saber elementar. Desta forma, os resultados deste estudo auxiliam o desenvolvimento de um conhecimento histórico que tem por finalidade a compreensão da trajetória da estruturação e evolução da educação profissional técnica brasileira.
Princípios orientadores da prática docente e da formação continuada de profissionais da educação infantil
Authors: Oliveira Lucilene Simone Felippe , Rausch Rita Buzzi
Published: September 2024

Esta investigação objetiva identificar os princípios orientadores da prática docente e da formação continuada de profissionais da Educação Infantil de uma rede municipal do Norte Catarinense. Por meio de uma pesquisa qualitativa e sócio-histórica, foram realizadas entrevistas semiestruturadas com coordenadoras pedagógicas, aplicada a técnica de complemento e grupo de interlocução com professoras e auxiliares de sala. Foi também submetido um questionário às assessoras pedagógicas da Secretaria Municipal de Educação e feita uma análise de documentos. Para a análise de dados, o presente estudo ancora-se na Análise de Conteúdo de Bardin. Os resultados evidenciaram três princípios orientadores da prática docente e da formação continuada de profissionais da Educação Infantil: princípios éticos, estéticos e políticos; a criança como protagonista; e as interações e as brincadeiras. Quando a formação continuada de profissionais da Educação Infantil considera os mesmos princípios da prática docente, compreende-se que os profissionais têm mais chances de se desenvolverem profissionalmente.
Niños, niñas y adolescentes en las zonas cocaleras del VRAE y el Alto Huallaga
Authors: Novak Fabián , Namihas Sandra , Huamán Milagros , García-Corrochano Moyano Luis
Published: September 2024

La utilización de los niños, niñas y adolescentes en actividades vinculadas al narcotráfico en las zonas cocaleras como objeto de estudio, es relativamente reciente dadas las dificultades geográficas y de seguridad existentes en las regiones donde se desarrolla con mayor intensidad la actividad cocalera, que complican y en algunos casos anulan el acceso a la información. Sin embargo, es un fenómeno que se desarrolla en nuestra realidad social y que por tanto, debemos conocer en profundidad si queremos transformarlo y darle solución. Por estas razones, para el presente estudio era necesario emplear el método científico de investigación, esto es, la interacción continua entre la experiencia de campo y la teoría; iniciando la investigación con el abordaje de toda la documentación existente, para luego verificar la información con la observación empírica de la realidad. En este sentido, para la presente publicación se han aplicado dos técnicas de investigación en forma paralela a efectos de consultar todas las fuentes disponibles: a) Investigación de gabinete, mediante la cual se han consultado las diversas fuentes normativas, bibliográficas y hemerográficas ya publicadas sobre la temática (normas internacionales e internas, libros, revistas, periódicos, medios electrónicos, informes, documentos, etc.). b) Investigación de campo, mediante la cual se ha obtenido información basada en fuentes primarias, esto es, a través de la observación directa del fenómeno y la realización de entrevistas -a autoridades, víctimas, testigos y pobladoresestructuradas (sustentadas en un cuestionario preestablecido) y semi-estructuradas (conversaciones basadas en ideasfuerza) en el valle del río Apurímac y Ene (VRAE) y el Alto Huallaga
Las relaciones entre el Perú y la Unión Europea
Authors: Novak Fabián , Namihas Sandra
Published: September 2024

Una de las principales líneas de investigación del Instituto de Estudios Internacionales (IDEI) de la Pontificia Universidad Católica del Perú es la Política Exterior Peruana y, dentro de ella, aquellos aspectos poco profundizados o explorados en la literatura nacional. Este es el caso precisamente de nuestras relaciones con la Europa comunitaria, no obstante los importantes niveles de comercio, inversión, cooperación y diálogo político existentes entre ambos. En este sentido, el IDEI se planteó llevar adelante esta investigación, con el apoyo de la Fundación Konrad Adenauer (KAS), la misma que busca ampliar las perspectivas del trabajo que viene realizando en el continente. La KAS consideró, desde un inicio, que este proyecto se enmarcaba dentro de sus propósitos institucionales en tanto el mismo busca poner en conocimiento fundamentalmente del público peruano y europeo la evolución y la situación actual de la relación entre la Unión Europea y el Perú, para así buscar puntos de convergencia y fortalecer las relaciones entre ambos.
Lineamientos y aristas de la política exterior peruana en el nuevo orden del siglo XXI (a propósito del bicentenario del MRE)
Authors: Novak Fabián , Namihas Sandra
Published: September 2024

Dicha investigación realizada por sus autores, Fabián Novak y Sandra Namihas, presentó en casi trescientas páginas los orígenes y la evolución de esta renombrada institución. En una segunda etapa de este proceso de análisis sobre la Cancillería del Perú, a modo de secuela, tenemos el honor de presentar en esta ocasión la obra Lineamientos y aristas de la política exterior peruana en el nuevo orden del siglo XXI. (A propósito del bicentenario del MRE). Sus autores, con una mirada vanguardista y comprendiendo los sucesos de actualidad, nos presentan un análisis detallado de los avances y logros en distintos niveles tanto del ámbito institucional, como en la propia política exterior peruana, para el fortalecimiento y modernización de la institución. En este análisis destaca tanto la elección de los temas investigados como las recomendaciones para las acciones futuras. El lector puede encontrar en este libro no solo una diestra investigación académica, sino una obra que aporta, desde la academia, a la generación de políticas públicas, en el contexto del nuevo orden internacional del siglo XXI y de la situación política regional y local.
Organizational Behavior And Culture In Education
Authors: Septianto Saleh Yusuf Yusian , Arifiani Bilqis Fathimatus
Published: September 2024

Organizational behavior is a field of study that examines habits, behavior, and the impact of individual involvement with organizations that influence processes within organizations such as in organizations or educational institutions. Organizational culture in education is something that is carried out continuously, making it a characteristic of an educational institution. Organizational behavior and culture in education is a unit that forms a structured system and shapes individual behavior patterns in organizations or educational institutions. The objectives of this research are 1) the concept of organizational behavior in education; 2) the concept of organizational culture in education; 3) behavioral and cultural characteristics of educational organizations. The research method used is a library study that focuses on literature, books, notes and published scientific information. The results of this research are 1) organizational behavior is a study that discusses individuals to obtain information in making decisions to make rules that can be used according to the conditions and situations of the educational environment; 2) organizational culture is the basic assumptions developed within an organization, to serve as a guide for the attitudes and behavior of all its members; 3) the characteristics contained in organizational behavior and culture in education are habits that are carried out repeatedly or continuously in learning to produce a certain behavior and culture that has characteristics that are different from other aspects.
Modelo explicativo de síntomas de tensión en familiares de personas con problemas de consumo de alcohol
Authors: López Charles Estefany Marlene , Guzmán Facundo Francisco Rafael , Quintero Domínguez Ricardo Azael , Candia Arredondo Josefina Sarai , López García Karla Selene
Published: September 2024

Objetivo: Analizar los efectos que producen el consumo de alcohol en un miembro familiar, las situaciones estresantes, las estrategias de afrontamiento, el apoyo social, la esperanza y la funcionalidad familiar sobre los síntomas de tensión en familiares de personas con problemas de consumo de alcohol. Materiales y métodos: El diseño fue de tipo descriptivo correlacional, transversal y de comprobación de modelo. El muestreo fue no probabilístico por cuotas. La muestra fue de 161 consumidores de alcohol y familiares. Se emplearon siete instrumentos. Resultados: Se identificó que el consumo de alcohol de una persona presentó un efecto positivo con las situaciones estresantes de un familiar (p < ,05). Se mostró que la presencia de situaciones estresantes presenta un efecto positivo sobre la tensión en el familiar (p < ,001). Se verificó que los estilos de afrontamiento (p < ,05) y el apoyo social (p < ,05) son factores que pueden reducir el efecto de los estresores sobre la tensión. También se demostró que la funcionalidad familiar (p < ,05) y la esperanza (p < ,001) reducen el efecto de los estresores sobre la tensión en familiares de personas con problemas de alcohol. Conclusión: Los estilos de afrontamiento, el apoyo social, la funcionalidad familiar y la esperanza son factores mediadores para reducir el efecto de las situaciones estresantes sobre la tensión en familiares con personas con problemas de alcohol. Contar con modelos teóricos probados empíricamente permitirá en un futuro el desarrollo de intervenciones de enfermería para mejorar el bienestar familiar.
“Tıp ve Sanat” Dersi İle İlgili Tıp Fakültesi Öğrencilerinin Görüşleri: Nitel Bir Araştırma
Authors: Akdoğan Ilgaz , Akdogan Hayriye Dilek
Published: September 2024

Tıp eğitiminin temel amacı olan “iyi hekim” yetiştirmek için sanat önemli bir araçtır. Sanat hekimlerin hem hastalarını hem kendilerini daha iyi anlamak ve mesleki uygulamalarda hastalarına daha yararlı olmak için kullanılabilen bir öğedir. Aydın Adnan Menderes Üniversitesi Tıp Fakültesi 2022-2023 Eğitim-Öğretim Yılı Dönem-1’de ilk olarak seçmeli “Tıp ve Sanat” dersi uygulanmıştır. Dersin içeriği sanatın temel bileşenlerinin (resim, edebiyat, sinema, müzik, heykel, mimari) tıp ile ilişkisinin incelenmesi şeklinde planlanmıştır. Bu çalışmanın amacı Aydın Adnan Menderes Üniversitesi Tıp Fakültesi’nde uygulanan “Tıp ve Sanat” dersi ile ilgili öğrenci görüşlerini incelemektir. Bu çalışma Aydın Adnan Menderes Üniversitesi Tıp Fakültesi Dönem-1’de seçmeli olarak uygulanan Tıp ve Sanat dersini 2022-2023 Eğitim-Öğretim Yılında alan toplam 20 öğrenciden, bir eğitim öğretim yılı sonrasında (Dönem-2’deki) gönüllü 8 öğrenci ile nitel araştırma metotlarından yarı yapılandırılmış odak grup görüşmesi yöntemiyle görüşleri alınarak gerçekleştirilmiştir. Odak grup görüşmesine gönüllü olan öğrenciler katılmış ve görüşme yaklaşık bir saat sürmüştür. Öğrencilere sanatın temel bileşenleri ile tıp ilişkisi ve ders içeriği ile ilgili 8 adet soru yöneltilmiştir. Öğrenci yanıtlarının, farklı bakış açılarının olduğunu görmek, serbest tartışma ortamında düşüncelerini söyleyebilmeleri, hasta ve hasta yakınlarının psikolojilerini anlamada sanatın önemi, doktor hasta iletişiminde hastanın duygularını dikkate alma gibi konulara yoğunlaştığı gözlenmiştir. “Tıp ve Sanat” dersi ile ilgili öğrencilerin olumlu düşüncelerinin olduğu, odak grup görüşmesindeki yanıtların empati geliştirme, kişisel gelişim ve geniş düşünebilme becerileri gibi dersin amaçları ile uyumlu olduğu görülmektedir. Tıbbi çalışma alanlarına dâhil edilen sanatın, tıbbın konusu olan insanın biyopskikososyal olarak ele alınması anlayışına katkı sunduğunu düşünmekteyiz.
The role of N6-methyladenosine modification in neurodegenerative diseases
Authors: Song Junzhu , Yan Sen
Published: September 2024

In recent years, transcriptomics has emerged as a key focus in neuroscience research, as transcriptome modifications play a significant role in influencing various biological processes. N6-methyladenosine (m6A) represents a dynamic and reversible form of mRNA modification prevalent in eukaryotes. This modification is involved in virtually every critical stage of RNA metabolism, including mRNA stability, transcription, translation, splicing, nuclear export, and decay, thereby playing a pivotal role in normal brain development. Accumulating evidence suggests that m6A modification plays a substantial role in various neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington’s disease (HD), while abnormal m6A modification can lead to neurodevelopmental disorders. This review summarizes the relationship between m6A modification and various neurodegenerative diseases and elucidates its potential pathogenic mechanisms at the molecular level.
THE IMPACT OF PERCEIVED TOP MANAGEMENT SUPPORT ON JOB PERFORMANCE THROUGH JOB BURNOUT: EVIDENCE FROM THE HOTEL INDUSTRY
Authors: LAŠKARIN AŽIĆ Marina , CEROVIĆ Marta , IVANČIĆ Ivana
Published: September 2024

Purpose – This paper aims to examine the importance of job burnout when mediating the relationship between perceived top management support (TMS) and the dependent variables of job dedication and guest empathy deficiency. Methodology/Design/Approach – The study gathered data from hotel employees in Opatija who directly interact with guests. A total of 108 valid questionnaires were obtained through an on-site survey. The study employed the partial least squares method within the SmartPLS 4 programme to analyse causal relationships between independent and dependent variables. Findings – The results show that perceived TMS has a significant impact on employees’ empathy towards guests and their dedication to work only in the case when job burnout mediates this relationship, emphasizing the importance of further examining the consequences of burnout in high-intensity interactive service professions. Originality of the research – This paper offers new insights into the mediating role of burnout in the workplace. It is the first paper to examine direct and indirect relationships between perceived TMS and the impact on work engagement in both positive (job dedication) and negative (guest empathy deficiency) directions
Prediction Models for the Milling of Heat-Treated Beech Wood Based on the Consumption of Energy
Authors: Koleda Peter , Čuchor Tomáš , Koleda Pavol , Rajko Ľubomír
Published: September 2024

The article is focused mainly on verifying the suitability of data from experimental milling heat-treated beech wood and on investigation of the effect of technical and technological parameters of milling on the energy consumption of this process. The independent parameters of machining process are cutting speed, feed speed, rake angle, and hydrothermal modification of experimental wood material. Based on analysis of variance it can be argued that the greatest statistically significant effect on energy consumption have cutting speed and rake angle of the tool while the feed speed had the least influence. The measured data of cutting power during milling were used to build a regression model and validate it, while the most suitable type of model with correlation of 87 % is Classification and Regression Tree followed by model created by Random Forests method.
A New-Type Dynamic Vibration Fiber Sensor
Authors: Chang I-Nan , Chiu Chih-Chuan , Liu Wen-Fung
Published: September 2024

A new-type vibration sensor based on a fiber Bragg grating combining with a special structure-packaged design is proposed for monitoring the mechanical vibration signals. Three different sensing structures including the film squeeze type, new film squeeze type and elastic tape squeeze type are proposed for measuring the vibration signals with the frequency range from tens to thousands of Hz. In the comparison of experimental results, the new film squeeze structure has a nice sensing performance in the range from 100 to 1000 Hz with the sensitivity of 35 mV/V. For the elastic tape squeeze structure, the elastic tape is designed to encapsulate the optical fiber with a good frequency response from 1100 to 3100 Hz. In addition, by using the new film squeeze structure to measure the steady-state and non-steady-state vibration signals, the spectral components of sensing signals are analyzed by using the wavelet transformation for confirming the testing signals. These vibration fiber sensors can be applied in the measurement of high-end manufacture-facility vibration or earthquake vibrations etc.
Researches on Orthogonal Experiments of Submersible Proportional Short-Circuit Blowing Model Test Bench and BP Neural Network Prediction&Pearson Correlation Analysis
Authors: He Xi-guang , Huang Bin , Peng Li-kun , Chen Jia
Published: September 2024

Short-circuit blowing is an important technical means to ensure the rapid surfacing of submersible. In order to study the impact of seven multiple manipulation factors of three levels on blowing, a proportional short-circuit blowing model test bench had been built and L18(37) orthogonal experiments were carried out; then, using Back propagation neural network and Pearson correlation analysis, the experimental data were trained and predicted, correlation between individual factor and blowing was further studied as supplement of orthogonal experiments. It had been proved that both multi-factor combination and individual including blowing duration, sea tank back pressure, the gas blowing pressure of the cylinder group, and sea valve flowing area had larger influence, whose correlation coefficients were 0.6535, 0.8105, 0.5569, 0.5373, of which the F-ratio of blowing duration is over critical value 3.24. And statistical evaluation indicators of Back propagation neural network were between 10e-2 and 10e-13, relative error was less than 3%, and prediction error accuracy was 100%. Based on the results above, a reasonable prediction method for submersible short-circuit blowing had been formed and suggestions on engineering design and operations were proposed, including advantage of short-circuit blowing method, initial condition settings and manipulation strategy.
Stochastic Plantwide Optimizing Control for an Acrylic Acid Plant
Authors: Duque Amaya Andrés Felipe , Tusso-Pinzón Ricardo Andres , Ochoa Silvia
Published: September 2024

This work addresses the relevant control system design issue for an acrylic acid plant through the lens of plant-wide stochastic optimization control (S-PWOC). The S-PWOC framework involves stochastic optimization methods. An evaluation comparison between the proposed S-PWOC model and two conventional models, specifically the two-level identification method and the typical plant-wide decentralized control structure, is performed. Despite the increasing computational demands associated with S-PWOC, experimental results highlight its effectiveness in handling different forms of uncertainty. Notably, S-PWOC demonstrates improvements in economic viability, control efficiency, and reduction of safety risks during plant operations.
Geyikli Baba Zâviyesi ve Osmanlı Kuruluş Sürecine Etkisi
Authors: Akkuş Mustafa , Bağcı Büşra
Published: September 2024

Osmanlı Devleti’nin kuruluş süreci dervişlerin, fakihlerin, alplerin, gazilerin, ahîlerin, bacıların en aktif olduğu dönem olmuştur. Bu dönemde muhtelif dinî ve tasavvufî zümrelere mensup pek çok âlim ve mutasavvıf kendilerine tabi yüzlerce alp, talebe ve müritleriyle birlikte Osman Bey’in hâkimiyetindeki topraklara göç etmişler ve yaşamlarını burada idame ederek uçlarda yeni bir devletin neşvünema bulacağı ilmî ve kültürel ortamı hazırlamışlardır. Genellikle Horasan bölgesinden gelen ve Yesevi dervişleri olarak adlandırılan bu gruplar Anadolu’nun muhtelif şehirlerinde tekke ve zâviyeler açarak bölgenin vatan kılınmasında önemli faaliyetler gerçekleştirmişlerdir. Bu konuda etkin olanlardan biri de Osmanlı Devleti’nin ilk dönemlerinde Bursa’nın İnegöl yöresine yerleşen Geyikli Baba’dır. Müritleriyle birlikte Bursa’nın fethedilmesinde de görev alan Geyikli Baba, şehrin ele geçirilmesi ile birlikte kentin kırsal bölgesine yerleşerek gönülleri fethetmeye çalışmıştır. Bu dönemde kendi adına açılan zâviyesinde halkı irşad ederek bu toprakların Türkleşmesi ve İslamlaşmasına önemli katkılarda bulunmuştur.

İnegöl’de inşa edilen bu zâviyeye iki köy vakfedilerek ihtiyaçlarının vakfedilen köylerden gelen gelirlerle sağlanması amaçlanmıştır. Devlet tarafından varlığı tanınan ve desteklenen Geyikli Baba Zâviyesi’ne ihtiyaç duyulan şeyh, müezzin vb atamalar yapılmıştır. Uzun yıllar bölgede faaliyetlerini sürdüren bu yapı 19. yüzyılda Bektaşî tekkesine dönüşmüştür. Bir süre Bektaşî kimliği ile hizmet veren mezkûr zâviye, 1826 yılında Bektaşîliğin yasaklanması üzerine kapatılarak faaliyetlerine son verilmiştir. Ancak birkaç yıl sonra bazı Bektaşî zâviyelerinin açılması sırasında Geyikli Baba Zâviyesi de yeniden hizmet vermeye başlamış ve faaliyetlerine kaldığı yerden devam etmiştir.
Kaht-ı Ricâl Girdâbında Saltanat Sürmek: II. Mahmud ve Yönetici Kadro [1808-1826]
Authors: Saydam Abdullah
Published: September 2024

II. Mahmud tahta çıktığında devlet iç isyanlarla uğraşmakta ve Rusya ile savaşmaktaydı. Genç Padişah’ın hedefi savaşı bir an önce bitirmekti. Bunun için zafer kazanıp onurlu bir antlaşma imzalanmasını arzu etmekteydi. Ancak bu yıllarda devlet çok yönlü problemler ile karşı karşıya idi: Devlet kurumlarındaki hantallık, Yeniçeri Ocağı’nda düzensizlik, malî yapının bozukluğu, insanların umursamazlığı gibi. Bütün bunlardan daha önemli sorun Osmanlı kaynaklarında kaht-ı ricâl denilen devlet adamı vasıflarına sahip yöneticinin azlığı idi. Padişah’a yardımcı olmaları ve danışmanlık yapmaları beklenen bu zümre yeteneksizlik, tembellik, hainlik gibi olumsuzluklara sahipti. Aralarında çıkar çatışması mevcuttu. Kıskançlık, birbirleri aleyhinde çalışmak ve fesat çıkarmak yaygındı. Din ve devletin istikbali tehdit altında iken bile şahsi menfaatlerini korumaya çalışanların sayısı az değildi. Padişah’ın devleti ve toplumu daha güçlü hale getirmeye yönelik fermanlarının uygulanmadığı da sıklıkla görülmekteydi. II. Mahmud, devlet adamlarını bir vazifeye getirirken işin iyi yapılacağı beklentisi içerisinde olmaktaydı. Ancak görevin gereğinin yapılmadığı hallerde birkaç uyarıdan sonra azil yoluna başvurmaktaydı. Dolayısıyla istenen nitelikte ricâl bulunamaması sebebiyle oldukça sıklıkla tayin-azil sürecinin meydana geldiği görülmektedir. Bu araştırmada II. Mahmud’un bizzat yazdığı yazılar ön planda tutularak konunun incelenmesine çalışılmıştır.
A Comparison of Proximal Patellar Realignment vs. Medial Patellofemoral Ligament Reconstruction
Authors: Layson James T. , Choy Kenneth , Cohn Randy M. , Scuderi Giles R.
Published: September 2024

» Patellar instability is challenging to address, and although there are many surgical options, proximal patellar realignment (PPR) and medial patellofemoral ligament (MPFL) reconstruction are both used—recently, the MPFL reconstruction has become more popularized.

» Both procedures have demonstrated similar recurrent dislocation rates and rates of arthritic progression.

» PPR is a cost-efficient procedure using just suture alone as compared with MPFL reconstruction, which uses different grafts and methods of fixation.

» PPR has demonstrated durable results, with a lower overall complication rate, much of which is caused by the MPFL reconstruction having unique complications due to fixation methods.

» The PPR is a beneficial procedure and should still be considered when dealing with patellar instability.
Resilience: How Academics Stay After Multiple Psychological Contract Breaches
Authors: Firmansah Yayan , Abdul Hamid Zabeda , Mhd Sarif Suhaimi
Published: September 2024

This qualitative phenomenological study explores the lived experiences of academics who have encountered multiple breaches in their psychological contracts within academic institutions. Through in-depth interviews with participants from diverse disciplines and career stages, the study investigates the coping mechanisms and adaptations in daily work activities employed by academics to navigate the emotional aftermath of psychological contract breaches. The findings reveal a multifaceted landscape of resilience, encompassing strategies such as seeking social support, engaging in professional development, utilizing creative outlets, and intentionally cultivating autonomy. Furthermore, adaptations in daily work activities include reorienting research focus, innovating teaching methodologies, embracing interdisciplinary collaborations, and committing to continuous learning. Comparisons with existing literature underscore both consistent themes and novel dimensions, contributing to a nuanced understanding of academic resilience. The study concludes with actionable recommendations for institutions to support the well-being and resilience of academics, emphasizing the importance of autonomy, interdisciplinary collaboration, and reflective practices. Future research directions are also proposed to deepen our understanding of academic resilience in the face of evolving challenges within the contemporary academic landscape.
PERLINDUNGAN HUKUM BAGI PEMBELI DALAM PEMBELIAN BARANG MELALUI JASA TITIP ONLINE
Authors: Zayyan Dhaifina
Published: September 2024

Dengan adanya perkembangan teknologi memberi kemudahan manusia untuk mencukupi kebutuhan dengan sistem jasa titip beli secara online. Akan tetapi, pada kenyataannya tidak berjalan mulus sehingga memungkinkan terjadinya wanprestasi. Penelitian ini merupakan penelitian yuridis normatif dengan pendekatan peraturan-undangan dan konsepsi, Sumber data dalam penelitian ini adalah data sekunder, Pengumpulan data diperoleh dengan studi kepustakaan. Hasil penelitian ini menunjukkan (1) keabsahan perjanjian jual beli online antara pembeli dengan pihak jasa titip online dengan Merujuk pada Pasal 1320 KUHPerdata maka perjanjian tersebut sah. Namun, sepanjang Merujuk Pasal 18 Ayat (1) Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik dan Pasal 1338 Ayat (1) KUHPerdata maka perjanjian tersebut sah mengikat para pihak yang membuatnya. (2) Perlindungan secara preventif atas transaksi antara pihak jasa titip online dengan pembeli maka telah diatur dalam pasal 9 Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik dan pasal 48 ayat (1) dan (4) Peraturan Pemerintah Nomor 71 Tahun 2019 tentang Penyelenggaraan Sistem dan Transaksi. Sedangkan secara represif, maka dapat mengacu pada Pasal 19 Undang-Undang Nomor 8 Tahun 1999 tentang Perlindungan Konsumen. Akan tetapi, sampai saat ini Undang-Undang Informasi dan Transaksi Elektronik dan Peraturan pelaksananya belum mengatur mengenai sanksi apabila pihak jasa titip online melakukan wanprestasi.
Kata Kunci : Jasa Titip Online,  Perjanjian, Wanprestasi
PERKAWINAN BEDA AGAMA DALAM PERSPEKTIF PRESERVATION OF DIN
Authors: Wati Ratma - , Hidayat Iman Nur , Mahmud Hafini bin , Kanggas Fazari Zul Hasmi , Akmal Haerul , Arif Achmad Arif
Published: September 2024

Pernikahan beda agama menjadi permasalahan yang cukup serius di negara Islam. Dikarenakan adanya penyimpangan terhadap syariat yang telah diturunkan oleh agama, akan tetapi di beberapa negara pernikahan beda agama seakan menjadi hal yang biasa dan bahkan pelaksanaannya didukung dengan peraturan. penelitian ini merupakan penelitian normative, deskriptif evaluative dan pendekatan yang digunakan adalah pendekatan perundang-perundangan, konseptual dan perbandingan pernikahan beda agama di negara Indonesia, Malaysia dan Brunei Darussalam. Hasil penelitian menunjukkan bahwa aturan pernikahan beda agama di Indonesia, Malaysia dan Brunei diatur di dalam undang-undang setiap negara dengan menyesuaikan kecenderungan yang terdapat di setiap negara, walaupun demikian praktek-praktek pernikahan beda agama tidak dapat dibenarkan dalam preservation of din perspective, karena pernikahan merupakan perintah agama yang ditujukan untuk menjaga agama itu sendiri, sehingga Ketika pernikahan beda agama dilakukan maka akan menghilangkan unsur-unsur yang terdapat dalam agama, dan apabila unsur-unsur tersebut telah hilang maka hilanglah penjagaan terhadap agama
Pelatihan Penulisan Karya Ilmiah Bersama Mahasiwa XYZ di Mesir Paper Writing Training with Indonesian Students XYZ di Mesir
Authors: Arroisi Jarman
Published: September 2024

Requests from Gontor alumni who are studying in Egypt to provide scientific manuscript writing training are very high. Their reasons are very basic because students during their Egyptian studies are not required to write papers or theses as their final assignments. This Community Service (PkM) aims to provide writing training so that Egyptian students who are members of the Pondok Modern Gontor Family Association (IKPM) have provisions for Masters studies. In the preparation of the paper, the author uses a descriptive-analytical method. With the zooming method, this scientific writing training can be carried out with the following results. First, students get a training model for writing scientific papers in general through nine stages. Second, students get guidance on how to write paragraphs and continue with how to quote correctly. Third, students get access to literature references from several national and international journals and various book references from online media. Fourth, students receive training and practice in writing scientific papers with a monitoring and clinic pattern once a week.
Reconcile Large Multi-Regional Input-Output databases using Generalized Minimal Residual method and fast computing
Authors: abdaoui abderrazak , Onat Nuri , Kucukvar Murat
Published: September 2024

In the design of multi-regional input-output (Multi-RegionalInput-Output (MRIO)) databases, data has to be reconciled from several sources. This requires looking for an equilibrated MRIO table that fits data from each source. The performances of the current data reconciliation methods, which mostly use RAS-type algorithms, is quite constrained. Furthermore, the mathematical underpinnings of RAS-type algorithms are not fully understood, and they are limited in their ability to handle particular constraints. Some methods, like the Least-Squares and Chebychev, have been shown to have a solid mathematical foundation. Still, they come with extra complexity regarding the number of iterations and computation needs. This paper proposes the integration of the Generalized Minimal Residual Method to reconcile many data sources for the MRIO databases. The comparison of the Generalized MinimalResidual (GMRES)’s convergence with the availability centered inventory model (Availability Centered Inventory Model (ACIM)) method for reconciliation shows its rapidity and robustness. In addition, the results show the low complexity of the GMRES compared to other existing methods.
Keywords: Multi-regional input-output (MRIO), Sustainability, ACIM method, GMRES method, Data Conciliation, System Resolution.
Inhibition of novel human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer
Authors: Califano Joseph , Nakagawa Takuya , Luebeck Jens , Zhu Kaiyuan , Lange Joshua , Sasik Roman , Phillips Chad , Sadat Sayed , Javadzadeh Sara , Yang Qian , Wang Allen , Pestonjamasp Kersi , Rosenthal Sara , Fisch Kathleen , Mischel Paul , Bafna Vineet
Published: September 2024

Extrachromosomal circular DNA (ecDNA) have been found in most types of human cancers, and ecDNA incorporating viral genomes has recently been described, specifically in human papillomavirus (HPV)-mediated oropharyngeal cancer (OPC). However, the molecular mechanisms of human-viral hybrid ecDNA (hybrid ecDNA) for carcinogenesis remains elusive.
We characterized the epigenetic status of hybrid ecDNA using HPVOPC cell lines and patient-derived tumor xenografts, identifying HPV oncogenes E6/E7 in hybrid ecDNA were flanked by novel somatic DNA enhancers and HPV L1 enhancers, with strong cis-interaction. Targeting of these enhancers by clustered regularly interspaced short palindromic repeats interference or hybrid ecDNA by bromodomain and extra-terminal inhibitor reduced E6/E7 expression, and significantly inhibited in vitro and/or in vivo growth only in ecDNA(+) models. HPV DNA in hybrid ecDNA structures are associated with novel somatic and HPV enhancers in hybrid ecDNA that drive HPV ongogene expression and carcinogenesis, and can be targeted with ecDNA disrupting therapeutics.
Effect of hydrotalcites in tannate conversion coatings for iron artefacts
Authors: Košťúr Roman , Dujnič Viera , Tomanová Katarína , Červenková Andrea , Zemanová Matilda
Published: September 2024

The surface treatment of iron artefacts requires an application of the proper conservation coating to prevent further corrosion deterioration. Tannate coating is preferred as a conservation agent of iron/steel with the desired black appearance of the surface. In this work the modification of the tannate coating with hydrotalcites to improve conservation ability was studied. Methodology of the surface treatment was developed, and process parameters: hydrotalcite addition, applied layers, immersion time and pH of the stock solution were studied. The treated surface was characterised by various methods e.g. Raman spectroscopy, EDX measurements and electrochemical characterization and the quality of the surface treatment was evaluated with respect to cyclic QUV test. Effect of hydrotalcite addition on quality of the conversion coating was confirmed and explained by incorporation of Al in the coating. Mechanism of the modified conversion coating was proposed.
The Association Between Real Life-Assessed Sit-to-Stand and Stand-to-Sit Kinematics with Self-Reported Levels of Physical and Mental Fatigue in Neurodegenerative and Immune-Mediated Inflammatory Diseases
Authors: Romijnders Robbin , Atrsaei Arash , Rehman Rana , Strehlow Lea , Massoud Jèrôme , Hinchliffe Chloe , Macrae Victoria , Emmert Kirsten , Reilmann Ralf , Woude Christien van der , Gassen Geert van , Baribaud Frédéric , Ahmaniemi Teemu , Chatterjee Meenakshi , Vitturi Bruno , Pinaud Clémence , Kalifa Jérôme , Avey Stefan , Ng Wan-Fai , Hansen Clint , Manyakov Nikolay , Maetzler Walter
Published: September 2024

Fatigue is a complex, multi-faceted phenomenon that is particularly common in immune-mediated inflammatory disease and neurodegenerative disease cohorts. Clinical assessment of fatigue relies heavily on patient-reported outcomes (PROs), that provide only the perception aspect of fatigue and poorly capture fluctuations over time. The use of wearable sensors, e.g., inertial measurement units, overcome these drawbacks, by allowing for the assessment of capacity and performance aspects of health through continuous monitoring of daily life activities. However, the relation between daily life activities that are prerequisite for functional independence, such as sit-to-stand and stand-to-sit transitions, and fatigue, is not well established, thus this study aims to quantify the association between kinematic features of sit-to-stand and stand-to-sit transitions and self-reported physical and mental fatigue. Study participants wore an IMU on the lower back for four consecutive weeks, and continued their daily life activities as usual, thereby reporting their physical and mental fatigue four times per day on a 7-point Likert scale via a smartphone application. Sit-to-stand and stand-to-sit transitions were detected using a validated algorithm, and kinematic features were derived from those transitions. The association between the kinematic features and PROs were researched using mixed effects models, with fatigue modelled as the independent variable and the median, 95th and 5th percentiles of the kinematic features from a 2-hour aggregation window centred around the time of administration of a PRO. The results suggested 5th and 95th percentiles of selected kinematic features were associated with fatigue across different disease cohorts. Furthermore, it was hypothesised that with more fatigue standing up is performed with more effort that is needed, whereas with more physical fatigue sitting down is performed with less control of the body movement, i.e., people drop down on their chair or sofa. In conclusion, this study showed the potential of selected kinematic features of sit-to-stand and stand-to-sit movements as intermediate clinical endpoints to reflect aspects of fatigue.
Maintenance pharmacotherapy after electroconvulsive therapy in inpatients with major depressive disorder: 198 prescriptions in a real-world clinical setting
Authors: Igarashi Shun , Tsuboi Takashi , Hasegawa Naomi , Ochi Shinichiro , Ohi Kazutaka , Fukumoto Kentaro , Iga Jun-ichi , Muraoka Hiroyuki , Iida Hitoshi , Kodaka Fumitoshi , Numata Shusuke , Ichihashi Kayo , Kashiwagi Hiroko , Nakamura Toshinori , Yamagata Hirotaka , Takeshima Masahiro , Nagasawa Tatsuya , Matsumoto Junya , Yamada Hisashi , Hori Hikaru , Inada Ken , Yasui-Furukori Norio , Hashimoto Ryota , Watanabe Koichiro
Published: September 2024

Background: Although antidepressant monotherapy is recommended for patients with major depressive disorder (MDD), they often do not respond to it, necessitating alternatives such as electroconvulsive therapy (ECT). However, maintenance pharmacotherapy after ECT has remained unestablished. With the aim of exploring real-world post-ECT maintenance pharmacotherapy, we conducted a large-scale retrospective observational study to investigate the prescription patterns at discharge in hospitalized patients with MDD.
Methods: The study was implemented as part of the EGUIDE (Effectiveness of Guidelines for Dissemination and Education in Psychiatric Treatment) project, which has been published in several previous studies, and was conducted between 2016 and 2019 at 240 facilities throughout Japan that participated in the project. The 3,794 patients with MDD included in this study were divided into two groups, one that underwent ECT during hospitalization (ECT group, N = 521) and another that did not (non-ECT group, N = 3,273), for the comparison of clinical characteristics and prescription details at discharge. Statistical analyses were performed using IBM SPSS Statistics 28.0.0 (190) (IBM Japan, Tokyo, Japan). Student's t-test and chi-square test were used for statistical analysis. Bonferroni's correction was used to adjust for multiple comparisons in all chi-square tests, and a p-value of less than 1.4 x 10-3 was defined as significant.
Results: We identified 198 prescription patterns involving antidepressants in the ECT group. Analysis by drug category revealed distinctive patterns: there was no statistically significant difference in prescription rates for antidepressant monotherapy between the ECT and non-ECT groups (N = 118, 22.6% vs. N = 932, 28.4%), while the prescription rate for the combination of antidepressant monotherapy and lithium monotherapy in the ECT group was significantly higher than in the non-ECT group (N = 30, 5.7% vs. N = 35, 1.0%). Regarding the combination treatment with antidepressants and atypical antipsychotics, the ECT group (N = 188, 36.0%) was significantly higher than the non-ECT group (N = 941, 28.7%).
Conclusions: These findings highlight the complexity of treatment decisions managing of MDD after ECT and emphasize the need for structured prospective research on the effectiveness of specific maintenance pharmacotherapies after ECT.
Measurement of Copper, Zinc, Lead, and Chromium in Marine Mud Samples by Microwave Digestion ICP-OES Using Chemometric t- Test
Authors: Wang Shujia , Guan Jinan , Wan Lihua , Lu Jingsheng , Zheng Qiaoqing , Chen Kaiyue
Published: September 2024

Establishing an analytical method to interpret trace element changes is crucial for methane hydrate seepage tracking, exploration, and exploitation. However, research on this important issue is still limited, posing a challenge for trace element determination in marine mud samples. In this study, we first applied t-tests on independent samples for XRF tests with soil QC samples and sea mud samples. The results showed no statistically significant difference between sea mud samples and soil QC samples. Thus, soil QC samples were used for the methodology study.
We investigated the microwave digestion procedure, the selection of spectral line wavelengths for analytical tests, the limit of detection (LOD) and quantification (LOQ), spiked recoveries, precision, accuracy, and the interference of coexisting elements on spectral line selection. Results indicated that the use of inverse aqua regia and 1 mL HF as a mixed acid system is effective. Copper and zinc elements require temperatures above 150 °C, lead and cadmium above 180 °C, and chromium should not exceed 210 °C to avoid volatilization. Analytical spectra for copper, zinc, chromium, and lead were selected at 324.752, 213.857, 267.716, and 220.353 nm wavelengths. The correlation coefficients of the standard curves were above 0.9997, with detection limits ranging from 0.0004 to 0.0105 mg/L and quantification limits from 0.0017 to 0.0419 mg/L. Spiked recoveries ranged from 95.5% to 103.7%. The method's accuracy was verified using soil standard samples (GSS-4 and GSS-5). The ICP-MS method tested sea mud samples for t-test comparison, and statistical results showed no significant difference.