bluuebunny/crossref_metadata_2025 huggingface dataset:
Partially thrombosed distal posterior cerebral artery aneurysm treated with surgical trapping through occipital transtentorial approach assisted by endovascular coil embolization
Authors: Nambu Kosuke , Kamide Tomoya , Tsutsui Taishi , Kitabayashi Tomohiro , Yoshikawa Akifumi , Misaki Kouichi , Nakada Mitsutoshi
Published: January 2023

Background:

Posterior cerebral artery (PCA) aneurysms are relatively rare. PCA aneurysms tend to be large, giant, fusiform, and partially thrombosed. Surgical treatments, such as neck clipping and trapping with or without bypass surgery, are curative treatments for thrombosed intracranial aneurysms. Few cases of surgical treatment of distal PCA aneurysms have been reported. We treated a partially thrombosed distal PCA aneurysm by trapping through the occipital transtentorial approach (OTA) assisted by endovascular coil embolization.

Case Description:

A 21-year-old woman presented with a sudden headache. Brain computed tomography, magnetic resonance imaging, and a cerebral angiogram revealed a partially thrombosed aneurysm in the left PCA P3 segment. Her headaches had improved once within several days, but reoccurred due to an enlarged thrombosed aneurysm. Endovascular coil embolization was performed to assist the surgery. The aneurysm and the distal artery of the aneurysm were embolized to interrupt the blood flow into the aneurysm. The following day, trapping of the aneurysm was performed through the OTA. Eventually, we performed aneurysm excision because trapping alone was considered to have the potential for regrowth of the aneurysm. The patient’s postoperative course was uneventful. No recurrence of the aneurysm was observed at the 2-year follow-up.

Conclusion:

OTA could be useful for the treatment of distal PCA aneurysms, whereas coil embolization may support the surgical treatment of partially thrombosed intracranial aneurysms.
Spatiotemporal variation of landslide using the projected rainfall data from climate change scenario
Authors: . Thongley , Wangmo D. , Sharma V. , Choden K.
Published: January 2023

The adverse change in weather increases landslide risk every year due to climate change. Consequently, developmental activities were hampered due to the landslide. This study aimed at developing past landslides (1997, 2007, 2017) using national rainfall data and projected landslides for the years 2027, 2037, 2050 and 2100 using the projected rainfall data in three districts of Bhutan namely Zhemgang, Mongar and Bumthang. The study uses elevation, aspect, slope, curvature, TWI, SPI, NDVI, distance from the river, distance from road, lithology and flow accumulation as influencing factors apart from different year rainfall data. The frequency ratio was employed for data analysis. Kappa index and accuracy were used to validate the landslide map for the year 2017. The landslide risk zones are classified into very low, low, moderate, high and very high. It is observed that the total area of the very low zone decreased from 1997 to 2100 while the area of the very high-risk zone increases from 1997 to 2100. Among the districts, the Zhemgang dzongkhag was highly susceptible to landslides. On the other hand, Bumthang district is least impacted by the landslides.
Preparation of eco-friendly adsorbents from Port Jackson (Acacia saligna) and its application in removal of basic dyes
Authors: Giwa Abdur-Rahim A. , Wewers Francois , Kayi Lilitha , Aderibigbe Deborah O.
Published: January 2023

In this study, the potential of two adsorbents prepared from Port Jackson (PJ) plant for the removal of Janus Green (JG) and Victoria Blue (VB) dyes from wastewater was investigated. One of the adsorbents was prepared from Port Jackson by employing the plant’s leaves in their natural form after washing while the second one was obtained by treating the leaves with concentrated sulphuric acid. The adsorbents were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). Batch adsorption experiments were conducted with different initial concentrations of dyes, adsorbents doses, temperatures and contact times to determine their effects on the process efficiency. Equilibrium isotherm, kinetics and thermodynamics of the processes were also evaluated. The percentage removal of the dyes by the two adsorbents increased with increasing contact time and adsorbent dosage but decreased with increasing temperature. The kinetics parameters obtained were found to follow pseudo-second order model, suggesting that the rate limiting step may be chemisorption. Thermodynamic studies reveal that the adsorption processes were spontaneous and exothermic in nature as evident from the negative values of Gibbs free energy (G0) and enthalpy (H0) obtained. The processes were accompanied with decreased randomness as shown in the negative change in entropy (S0). It can be concluded that the two adsorbents have good potentials for remediating JG and VB dye-contaminated wastewater.
Ultrasonic Degradation of Ciprofloxacin in the presence of Zinc Oxide Nanoparticles and Zinc Oxide/Acha Waste Composite
Authors: Ayanda O.S. , Amoo M.O. , Aremu O.H. , Oketayo O.O. , Nelana S.M.
Published: January 2023

In this study, zinc oxide nanoparticles (ZnO-NPs) and zinc oxide nanoparticles/acha waste composite (ZnO-NPs/acha waste) were synthesized via precipitation method to enhance the ultrasonic degradation of ciprofloxacin from aqueous solution. The ZnO-NPs and composite were characterized using Scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) and were used for the ultrasonic degradation of ciprofloxacin (CIP) in aqueous solution. The operating parameters such as sonication time (20-60min), ultrasonic amplitude (20-100%), pH (2-10), initial CIP concentration (3.125-50 mg/L) and catalyst dosage (0.02-0.1g) were examined for ultrasound only, ultrasound/ZnO-NPs and ultrasound/ZnO-NPs/acha waste treatment methods. The degradation experiment showed that a maximum degradation of 97.0% was achieved by the ultrasound/ZnO-NPs/acha waste method within 40 min when compared with ultrasound only (39.0%) and the ultrasound/ZnO-NPs method (85.0%). Moreover, the kinetic study indicated that the degradation of CIP with ultrasound catalyzed with ZnO-NPs is 6.5 times faster in comparison to ultrasound only whereas, the use of ultrasound with ZnO-NPs/acha waste is 10.6 times faster. Therefore, the ultrasound/ZnO-NPs/acha waste method has proven to be effective for the removal of pharmaceuticals from wastewater.
Cellulase Production by Pseudomonas fluorescens from Hexane Pretreated Waste Papers
Authors: Sneh Lata , Dhanya M.S.
Published: January 2023

The organic content in most of the municipal solid wastes primarily consists of post-consumer waste papers which are rich source of carbohydrates. The present study has focused on investigation of cellulase production by Pseudomonas fluorescens from different types of waste papers namely waste office paper (WOP), waste cardboard (WCB), waste newspaper (WNP) and waste tea cup (WTC) after pre-treatment with n-hexane. The waste papers at a solid loading of 5% (w/v) produced glucose in the range of 5.24 g/L (WTC) to 6.43 g/L (WOP) from n-hexane pre-treatment at 80oC for 30 minutes. The structural changes of pre-treated waste papers were studied by using Scanning Electron Microscope. Pseudomonas fluorescens (10% v/w) inoculated to pre-treated waste papers with 70% moisture content was able to produce maximum cellulase at 15 days of incubation with 5.10 CMCase/mL from WOP followed by cardboard and newspaper with similar production of 4.03 CMCase/mL and WTC with production of 3.82 CMCase/mL.
Procedure for chromatography using mobile phase with high elution strength to recover tacrolimus from the fermentation broth
Authors: Pavithra M.K.S.
Published: January 2023

A simple, accurate, cost effective and precise method of reverse phase - high performance preparative liquid chromatography was developed to maximize recovery and yield of tacrolimus and to bring down the concentration of analog impurities with relative retention time (RRT) 0.94 and 1.2 less than 0.5%, the two impurities that affect the assay of the product. For the high performance preparative liquid chromatography, Kromacil-C8, 13 μm column consisting of 10*250mm I.D. was used with the flow rate of 3.925 ml/min and eluent was monitored at 210 nm. In isocratic mode, mobile phase containing KH2PO4 Buffer: Acetonitrile: Butanol of varying ratios was used for the resolution study. The retention time was analyzed and gradient run was carried out for the mobile phase ratio that gives maximum resolution. The gradient run was carried out for two different trials with mobile phase in two different lanes. Loading trials were carried out for the trials which gave maximum resolution. The samples were analyzed and the yield on load was calculated for all the runs. The gradient run with gradient time of 200 mins and mobile phase ratio 22.2:77.8 to 28.8:71.2 acetonitrile:butanol:buffer gave 82% yield on the basis of load which was found to be maximum among all the trials carried out. Adsorption isotherm parameters were determined for the same.
Fiber Reinforced Polymer Composites: Classification, Chemical Treatment, Mechanical and Tribological Properties
Authors: Selvakumar P.
Published: January 2023

Composites are supposed to be the most promising and discriminating material available in this century. Presently, composites armoured with fibers of synthetic materials are gaining more significance as demands for lightweight materials with high potency for specific application are growing in the market. Fibre reinforced polymer (FRP) composites mainly comprise of high strength fibres embedded in polymer matrix keeping a distinct interface between them. In this FRP’s, the individual component keeps their distinct physical and chemical identities but they combine together to produce materials with excellent properties. Low density, high tensile strength and high modulus are the main characteristics of fibre reinforced polymer composites. The main factors that affect load carrying capacity are interfacial bonding between fibre and matrix, alignment of fibre in matrix and the nature of fibres. Here in this review a proportional account of the major synthetic and natural fibres as reinforcement for polymer composites as well as methods for enhancing mechanical properties are discussed. Composites reinforced with fibers of artificial materials are gaining more significance as demands for lightweight materials with high strong point for specific applications are being developing in the market.
Biomining: A Sustainable Solution for Reclamation of Open Landfills in India
Authors: Ghosh Nabanita , Hazra Tumpa , Debsarkar Anupam
Published: January 2023

Urban India produced around 62 MT of municipal solid waste (MSW) (450 gcapita-1day-1) in 2015. Approximately 82% of the generated MSW was collected and only 28% of the collected waste was treated and the remaining 72% was openly dumped. Open dumping is the popular MSW disposal practice in India due to budget constraints and lack of technological advancement. Open dumpsites are considered a potential threat to environment and human health since they contaminate land and water resources during migration of leachate and create air pollution in terms of release of landfill gases (LFGs) with high percentages of greenhouse gases and thus contribute to climate change. It also consumes valuable land which could be converted into revenue generated assets. In 2011, India needed 380 km2 areas for waste disposal which will be 660 km2 by 2030. In 2016, the India Government has amended the Solid Waste Management Rules (SWM) for effective and proper management of MSW and reclaim the large old dumps by closure and recommend rehabilitate by a feasible solution in terms of reduction of waste by biomining. Biomining concept is an innovative, environmentally acceptable, economically and practically feasible and rapid measure to remediate the old open landfill site to successfully bring to zero emission of LFGs and leachate and also reclaim the land reusability and zero maintenance. In this study, the concept and utility of biomining as a key part of sustainable landfill management especially for the rehabilitation of MSW dumpsites in different megacities in India have been discussed.
Optimization of Bioethanol Production from Molasses using Saccharomyces cerevisiae with Response Surface Method-Central Composite Design Approach
Authors: Ishmayana Safri , Zenisya Selvira , Fadhlillah Muhammad , Safari Agus , Soedjanaatmadja Ukun M.S.
Published: January 2023

Bioethanol is one of alternative energy sources produced by fermenting carbohydrate rich materials with microorganism, especially the yeast Saccharomyces cerevisiae. It can be produced from feedstock with high carbohydrate content such as sugary, starchy and lignocellulosic materials. Molasses is a sugar production byproduct that has high glucose and other simple sugar content and therefore it is easy to ferment compared to starch or lignocellulosic materials that require pretreatment before fermentation. In the present study, we determine the optimum condition that can produce the highest ethanol using response surface method-central composite design (RSM-CCD) approach. Yeast strain used in the present study was Fali yeast, which is a commercially available industrial bioethanol strain. The concentration of molasses used in the present study was 40% (w/v) and factors optimized in the present study were pH, agitation rate and fermentation time. Twenty experiments were run based on the RSM-CCD using batch method. The results of the present study showed that the optimum condition was achieved when the pH, agitation rate and time of fermentation were 2, 368 rpm and 104 hours respectively. The concentration of ethanol reached 10.12% (w/v) at the optimum condition based on the model obtained. Validation of the model showed that 10.02% of ethanol can be achieved when the optimum condition was applied in laboratory experiment, indicating a good agreement between the mathematical model and experimental result.
Synthesis and validation of water-soluble cationic biodegradable starch as a flocculant
Authors: Saiyad Mamta Mainak
Published: January 2023

All efforts must be made to preserve water's purity for the present and the future because it is necessary for environment's sustenance and for all living things including humans, vegetation and animals. This project is an experiment to synthesize a flocculant for industrial effluent and as a result grafted starch-based biodegradable polymer is created to benefit both natural and synthetic polymers. This research focused on creating water-soluble, cationic, biodegradable starch to use as a flocculant. The reactive groups of the starch, or hydroxyls, combine with the cations in the reagent to produce a complex. The complex can separate creating free radical sites on the polysaccharide backbone. The mechanism of free radical graft copolymerization of ethyl monomers onto starch is anticipated in the presence of molecular nitrogen. H+ may be replaced by Reactive group R i.e. (CH2 CH3)3 N - (Et3)N in highly Alkaline medium. The effect of flocculant is validated on industrial effluent by jar test with various coagulation treatments.
Age aspect of neurophysiological diagnostics of post-concussion syndrome in patients with mild blast traumatic brain injury
Authors: Chebotariova Lidia L. , Zavaliy Yurii V.
Published: January 2023

Introduction. It is generally accepted that age influences neuropsychological and neurophysiological findings due to a decrease in memory and attention in older age groups as a result of diseases and damage to the central nervous system of various origins. This should be taken into account when dealing with patients who underwent mild blast traumatic brain injury (mbTBI), and focus on standard characteristics considering the age factor.
Purpose: to investigate the influence of the age factor on the characteristics of cognitive evoked potentials in patients with post-concussion syndrome (PCS) in the long-term period of mbTBI.
Materials and methods. The study involved 41 patients with PCS aged 18-45 years (study group) and 30 healthy subjects (control group). The patients were in the late period of trauma (from 6 months to 3 years). The age distribution of patients in the study group was the following: 6 patients under 30 years old, 18 patients aged 31-40 years, 17 patients over 40 years old. Neuropsychological testing was performed according to the Montreal Cognitive Assessment Scale. Quantitative electroencephalography was performed according to standard parameters (sensitivity ‒ 70 μV/cm, time constant ‒ 0.1 s, filter ‒ 40 Hz).
The results. Neurophysiological testing using the CEP P300 method allows us to verify the dysfunction of brain activity in the form of attention and memory disorders in patients with PCS as a result of mbTBI in the chronic period of damage. Exceeding the upper limit of the age norm of P2 and P3 latency components of CEP P300 is statistically significantly associated with the presence of cognitive impairment in patients with PCS.
Conclusions. The CEP P300 method can be recommended for the use in the complex diagnostics of cognitive disorders in patients with PCS in the subacute and chronic periods of the injury. In the clinical interpretation of latency characteristics of CEP P300 components, it is reasonable to focus on standard parameters, including age factor.
DAMPAK PANDEMI COVID-19 TERHADAP PENGUNGKAPAN TANGGUNG JAWAB SOSIAL PADA SEKTOR FARMASI
Authors: Noviarty Helisa , Edryani Yuniarsih
Published: January 2023

Pandemi COVID-19 jelas memberi berbagai dampak dalam kehidupan sehari-hari, tak terkecuali perusahaan-perusahaan yang beroperasi di Indonesia, khususnya perusahaan-perusahaan sektor farmasi. Seperti yang telah kita ketahui, perusahaan sektor farmasi adalah perusahaan yang berfokus pada pelayanan kesehatan dalam bentuk penyediaan obat, mengembangkan ilmu dan teknologi pembuatan obat, hingga penyediaan dan pengembangan alat-alat kesehatan. Oleh sebab itu, ketika suatu negara terserang wabah pandemi, sektor farmasi memiliki peran penting untuk membantu negara tersebut menanggulangi pandemi yang terjadi. , penelitian ini akan meneliti mengenai “Dampak Pandemi COVID-19 Terhadap Pengungkapan Tanggung Jawab Sosial Pada Sektor Farmasi”. Hasil analisis konten dari PT Kimia Farma Tbk, PT Kalbe Farma Tbk, dan PT Indofarma Tbk menunjukkan bahwa pandemi COVID-19 berperan besar terhadap pengungkapan tanggung jawab sosial pada sektor farmasi. Dua dari tiga perusahaan yang menjadi subjek penelitian memiliki pengungkapan yang cukup tinggi dalam penanggulangan COVID-19 sebagai tanggung jawab sosial pada masa pandemi COVID-19. Mengenai bagaimana Tanggung Jawab Sosial (CSR) yang diaplikasikan dapat membantu menanggulangi bencana COVID-19, hal ini bisa dilihat dari pendistribusian kebutuhan masker, hand sanitizer, alat pelindung diri, multivitamin dan nutrisi, pelaksanaan vaksinasi, hingga program-program lainnya yang ditujukan untuk meringankan beban pasien COVID-19 dan tenaga medis, dalam mengatasi bencana nasional ini yang dinilai sangat membantu masyarakat, pasien, tenaga medis, dan pemerintah. Jumlah donasi yang diberikan juga tidaklash sedikit, PT Kimia Farma Tbk menyumbang Rp1 miliar, PT Kalbe Farma Tbk menyumbang Rp52 miliar, dan PT Indofarma Tbk menyumbang Rp1,2 miliar.
ANALISIS KINERJA KEUANGAN PADA INDUSTRI ALUMINIUM YANG LISTING DI BURSA EFEK JAKARTA
Authors: Aryasa Hence Made
Published: January 2023

Analisis kinerja keuangan merupakan salah satu bentuk sarana yang penting dalam mengkomunikasikan informasi perusahaan. Ini mungkin ditunjukkan dalam sebuah laporan, yang menggambarkan kinerja finansial perusahaan selama periode waktu tertentu. Laporan keuangan adalah nama untuk laporan ini. Agar laporan keuangan dapat bermakna bagi pihak-pihak yang berkepentingan, maka penting dilakukan analisis laporan keuangan, yaitu pemeriksaan hubungan antar pos-pos dalam laporan keuangan. Tujuan dari penelitian ini adalah untuk mengetahui analisis dari kinerja keuangan pada industri alumunium yang listing di Bursa Efek Jakarta. Analsis yang dilakukan dalam penelitian ini yaitu rasio likuiditas, rasio leverage, rasio efisiensi, dan rasio profitabilitas. Berdasarkan rasio secara keseluruhan pada perusahaan alumunium yang listing di Bursa Efek Jakarta berada di posisi berjalan dengan cukup baik.
ANALISA LAPORAN KEUANGAN SEBELUM DAN SESUDAH PANDEMI COVID 19 PADA PERUSAHAAN ROKOK YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Kurniawan Rudy , Damayanti Fera
Published: January 2023

Akibat pandemi Covid 19. pertumbuhan ekonomi pada tahun 2020 semakin terpuruk di berbagai negara dan berdampak pada perekonomian global. Aktivitas masayarakat dan aktivitas perusahaan dibatasi sebagai upaya pencegahan penyebaran virus ini. Kinerja keuangan perusahaan dan harga saham juga mengalami penurunan akibat dampak penyebaran covid 19. Penelitian ini bertujuan untuk menganalisis laporan keuangan perusahaan manufaktur sektor industri barang konsumsi sub sektor rokok, yang terdaftar di Bursa Efek Indonesia sebelum dan sesudah terjadinya pandemi covid 19 ini. Kemudian akan dilihat kecendrungan (trend) hasil analisa tersebut untuk diambil kesimpulan apakah pandemi covid19 berdampak atau tidak berdampak pada kinerja keuangan perusahaan.. Penelitian untuk mengetahui nilai pertumbuhan penjualan, perolehan laba, rasio likuiditas, rasio solvabilitas, rasio profitabilitas perusahaan rokok yang terdaftar di Bursa Efek Indonesia berdasarkan laporan keuangan tahun 2018 dan tahun 2019 (sebelum pandemi covid 19) dan laporan Keuangan Tahun 2020 (sesudah pandemi covid 19). Hasil penelitian menunjukkan bahwa pandemi covid 19 tidak berdampak terhadap kecendrungan (trend) hasil : pertumbuhan penjualan (sales growth), perolehan laba, current ratio sebagian besar perusahaan, cash ratio debt to assets ratio. Namun pandemi covid 19 berdampak terhadap kecendrungan hasil profitabilitas perusahaan.yaitu gross margin ratio, return on investment dan return on equity.
ANALISIS PENERAPAN GOOD CORPORATE GOVERNANCE TERHADAP NILAI KINERJA KEUANGAN PADA PERUM PERUMNAS PROJECT SUKARAMAI KOTA MEDAN
Authors: Batubara Tiwi Bastari
Published: January 2023

ABSTRAKGood Corporate Governance adalah rangkaian proses, kebiasaan, kebijakan, aturan dan institusi yang memengaruhi pengarahan, pengelolaan, serta pengontrolan suatu perusahaan atau korporasi. Penelitian ini bertujuan untuk mengetahui pengaruh Good Corporate Governance terhadap nilai kinerja pada perum perumnas project sukaramai II kota medan. Pada penelitian ini digunakan jenis data kualitaif. Sumber data dalam penelitian ini menggunakan data sekunder, yaitu data yang sudah dikumpulkan oleh pihak lain. Untuk mengumpulkan data dalam penelitian ini digunakan  metode wawancara kepada karyawan perum perumnas project sukaramai II. Untuk membahas penelitian ini digunakan teknik analisis data dengan pendekatan deskriptif kualitatif. Dengan  memberikan gambaran tentang keadaan pengaruh Good Corporate Governance terhadap nilai kinerja keuangan perum perumnas project sukaramai kota medan. Dapat disimpulkan bahwa skor GCG yang diperoleh Perum Perumnas Project Sukaramai II Medan selama tahun 2017-2021 berada diatas standart BUMN dan termasuk kedalam predikat “Sangat Baik”. Hasil penelitian ini menjelaskan bahwasanya good corporate governance memiliki pengaruh yang signifikan positif terhadap nilai perusahaan. Pengaruh Good corporate governance sangat signifikan positif terhadap kinerja keuangan. Kinerja keuangan memiliki pengaruh yang signifikan terhadap nilai keuangan.Kata kunci : Good Corporate Governance, Kinerja Keuangan, Nilai Kinerja Perusahaan ABSTRACT                 Good Corporate Governance is a set of processes, customs, policies, rules, and institutions that influence the direction, management, and control of a company or corporation.  This study aims to determine the effect of Good Corporate Governance on the performance value of Perum Perumnas Project Sukaramai II Medan City.  In this study, qualitative data types were used.  Sources of data in this study using secondary data, namely data that has been collected by other parties.  To collect data in this study used the interview method to employees of Perum Perumnas Project Sukaramai II.  To discuss this research used data analysis techniques with a qualitative descriptive approach.  By providing an overview of the state of the influence of Good Corporate Governance on the value of the financial performance of Perum Perumnas Project Sukaramai Medan City.  It can be concluded that the GCG score obtained by Perum Perumnas Project Sukaramai II Medan during 2017-2021 is above the SOE standard and is included in the "Very Good" predicate.  The results of this study explain that good corporate governance has a significant positive effect on firm value. The effect of Good corporate governance is very significant positive on financial performance.  Financial performance has a significant influence on financial value.Keywords: Good Corporate Governance, Financial Performance, Corporate Performance Value
META ANALISIS : PENGARUH AUDIT TENURE, SPESIALISASI INDUSTRI AUDITOR, LEVERAGE, DAN PROFITABILITAS TERHADAP AUDIT DELAY ( STUDI PADA BEBERAPA JURNAL PERIODE 2011-2021)
Authors: Ferisha Friska , Faizah Wynne Nurul , Belinda Cynthia , Meiden Carmel
Published: January 2023

Tujuan penelitian ini adalah untuk menguji pengaruh audit tenure, spesialisasi industri auditor, leverage, dan profitabilitas terhadap audit delay .Data yang dipakai dalam penelitian ini adalah data sekunder. Metode penelitian ini digunakan untuk dokumen meliputi pengumpulan dan analisis data berupa hasil penelitian dari skripsi dan jurnal dari sejumlah universitas yang berkaitan dengan topik pengaruh Audit Tenure, Specialization Industry Auditor, Leverage, dan Profitabilitas terhadap Audit Delay. Pengambilan data skripsi dan jurnal dari periode penelitian antara tahun 2011 – 2021. Data output skripsi dan jurnal yang diambil dan digunakan didapat dari internet seperti mengecek eprint beberapa universitas, beberapa web jurnal, dan lainnya. Penelitian ini menggunakan teknik pengambilan sampel non probability sampling, yaitu metode purposive sampling. Eleman-elemen sampel dipilih berdasarkan kebijaksanaan peneliti sendiri yaitu 21 sampe yang terpilih. Teknik analisis data yang digunakan bersifat kuantitatif dengan metode meta analisis.Hasil penelitian menunjukkan bahwa audit tenure berpengaruh negatif terhadap audit delay , adanya pengaruh signifikan leverage terhadap Audit Delay , profitabilitas berpengaruh terhadap Audit Delay, spesialisasi industri auditor berpengaruh terhadap Audit Delay.
DETERMINASI KESADARAN WP EMKM KOTA PONTIANAK DALAM MEMENUHI KEWAJIBAN PERPAJAKAN
Authors: Yunita Khristina , Grania Mustika Ira , Nurfauziah Tiya
Published: January 2023

This study trying to analyze the determination of WP EMKM to fulfill the taxation obligation. This study consists of three independent variables and one dependent variable. The independent variables in this study are understanding of tax regulations, tax officer services, and perceptions of indirect counter-achievement. The dependent variable in this study is taxation obligation. This research uses a survey method with WP EMKM as the respondents and already have tax id number. The results of the data analysis show that knowledge and understanding of taxes, tax officers services, and perceptions of counter-performance are simultaneously influence WP EMKM to fulfill their tax obligations.
Water Hyacinth Utilization: A New Perspective on the Smoke-salted Duck Egg Process in Three Different Blended Fuels
Authors: Sukarman Sukarman , Khoirudin Khoirudin , Mulyadi Dodi , Rahdiana Nana , Ashiedieque Apang Djafar
Published: January 2023

Smoke-salted duck eggs (SDEs) one of Indonesia's most well-known egg food preservation methods. It not only increases the shelf life of smoked-salted duck eggs, but it also imparts a distinguishable flavor and taste to them. The SDEs process requires a boiling/steaming process that requires fuel for about 30% of the total energy required. The water content in water hyacinth is around 90%, which provides an opportunity to be used as a fuel that eliminates the boiling/steaming process. The water hyacinth (Eichhornia Crassipes) has never been used to produce SDEs as an alternative energy source. The dry bulb's temperature was kept below 95 o C. The relative humidity was managed to keep above 40% for the first two hours and 30% for the next six hours for the three different blended fuels (TDBF) methods for smokesalted duck eggs. The TDBF smoking method has significantly benefited from water hyacinth in the smoked salted duck egg process. The high water content of water hyacinth is advantageous so that the boiling/steaming process is successfully eliminated. The smoke-salted duck eggs processed using the TDBF smoked method had an egg maturity of more than 60% after 1.5 - 2 hours and around 100% after 3 -6 hours
Seismic Site Classification Using the Multichannel Analysis of Surface Waves Method
Authors: Syamsuddin Erfan , Aswad Sabrianto , Assegaf Muhammad Alimuddin Hamzah , Rasimeng Syamsurijal , Sakka Sakka , Syamsuddin Syamsuddin , Nasri Muhammad , Syihab Mufly Fadla
Published: January 2023

The soil has a variety of qualities that affect its ability to support the weight of a structure. One of these features is soil stiffness, which can be determined using the surface wave method to prevent soil collapse. Multichannel Analysis of Surface Waves (MASW) is one of the non-invasive methodologies used in this study to investigate subsurface structures in North Sumatra, Indonesia. This method utilizes the dispersion properties of Rayleigh waves, producing a dispersion curve to get the shear wave velocity (Vs) through inversion. The shear wave velocity can be used to examine the soil stiffness qualities. The dispersion curve explains the relationship between shear wave velocity and depth, which can subsequently be used as a site class parameter. This survey uses three lines with one shot for each line which uses thirty geophones. The seismic source used is a gun with the type M16.38 Cal. Each line consists of 30 geophones with a distance of 5 m. The entire track is 160 m long and lasts for 2048 seconds with a sampling rate of 0.00025 seconds. The average shear wave velocity measured at three measurements was 372.5 m/s on line P1, 347.1 m/s on line P2A, and 311.0 m/s on line P2B, respectively. Overall, the soil classification on the P1 line is class C, and the P2A and P2B lines are class D, which is suitable for development planning areas.
Study of Single Diode Model of DSSC Based on Reduced Graphene Oxide as Counter Electrode
Authors: Aprilia Annisa , Yuliasari Fitri , Siregar R.E , Syakir Norman , Bahtiar Ayi , Safriani Lusi , Hidayat Sahrul , Hanipah Iip , Fitrilawati Fitrilawati
Published: January 2023

We studied the characteristic of reduced graphene oxide (RGO) as a counter electrode (CE) in Pt-free dye-sensitized solar cell (DSSC) using single diode model equation based on current density-voltage (J-V) measurement. The electrical characteristics of DSSC was investigated by electrochemical impedance spectroscopy (EIS) in order to knowing the catalytic properties of RGO as counter electrode. The RGO thin film as CE was deposited on fluorine-doped tin oxide (FTO) substrate and stacked with FTO/TiO2/ruthenium dye/mosalyte/RGO/FTO DSSC structure. The RGO film was obtained from GO (graphene oxide) film that was thermally reduced at 200°C for one hour under argon flow. The performance of DSSC with RGO as CE was characterized by current-voltage measurement and the interface between each layer was observed by Electrochemical Impedance Spectroscopy (EIS).   The device efficiency (η) of DSSC that used GO and RGO film as CE are 0.09% and 3.43%, respectively. DSSC parameters such as series resistance (RS) shunt resistance (RSH), and ideality factor (n) were obtained from J-V curve which analyzed using single diode model equation. All samples have a Rs value of 2 indicates that all devices have a good ohmic contact. The RSH of device using RGO-1mg/ml is increase (from 2850 to 3670 Ω.cm2) compared with GO indicate that thermal reduction is successes. The RGO film shows a comparable performance to Pt-conventional CE thus it is a good candidate as alternative of DSSC counter electrode.
The Role of Water in Carbon Dioxide Adsorption in Porphyrinic Metal-Organic Frameworks
Authors: Baumgartner Bettina , Prins P. Tim , Louwen Jaap N. , Monai Matteo , Weckhuysen Bert M.
Published: January 2023

Capturing and converting CO2 in photoactive, porous materials to mimic photosynthesis is not only an appealing but also an important approach to combat increasing CO2 concentrations. Porphyrinic Zr-based metal-organic frameworks (MOFs) incorporate a photoactive dye in a porous material and are therefore promising candidates for artificial photosynthesis. The photochemical conversion of CO2 relies on the interactions between CO2, the proton source H2O, and the photoactive sites in the MOF pores. However, our understanding of these interactions and the photoreaction mechanism is still rather limited. Here, we studied the initial step of the artificial photosynthesis: CO2 sorption and activation in the presence of water. We have developed a combined vibrational and visible spectroscopic setup to simultaneously monitor the adsorption of CO2 into porphyrinic Zr-MOFs, namely PCN-222 and PCN-223, and the photophysical changes in the porphyrin linker as function of water concentration. Computational simulations further corroborate the experimentally obtained adsorption enthalpies. We found a shift of CO2 sorption site from the Zr-cluster to the center of the porphyrin macrocycle when PCN-MOFs were brought in contact with humidity greater than the water pore condensation concentration. The shift in sorption site was accompanied by a bending of the porphyrin macrocycle, which induced a change in color and, thus, a change in spectral overlap with light. Furthermore, CO2/H2O competition experiments revealed that the exchange of CO2 by H2O is pore-size-dependent. Therefore, both humidity and pore-size allow to tune the CO2 sorption site, CO2 capacity, and light harvesting in porphyrinic MOFs, which are key factors for CO2 photoreduction.
Evaluation of polymers for stabilization pavements soils
Authors: Mohamed Mariko , Tamboura Moussa
Published: January 2023

New commercial polymers (ROCAMIX, TECOFIX, and EPS PM50-PM70) for the pavement soils stabilization were tested. Soil stabilizer can enhance the soil properties, which can improve ecological environmental problems such as soil erosion and slope instability. This study investigates the water-related physical and mechanical properties of soil stabilization using a polymer soil stabilizer solution synthesized from ROCAMIX, TECOFIX, and EPS PM50-PM70 polymers. The water properties test, mechanical and physical properties test were carried out in the laboratory. Also, the effect of ROCAMIX, TECOFIX, and EPS PM50-PM70 polymers was verified by field tests. The results revealed that ROCAMIX, TECOFIX, and EPS PM50-PM70 polymers can enhance the water-retaining property, strength property of soil, all of which increase with the increase of polymer concentration. In addition, field tests proved that ROCAMIX, TECOFIX, and EPS PM50-PM70 polymers were good effects on soil engineering. These results could be applied as a reference for ROCAMIX, TECOFIX, and EPS PM50-PM70 polymers-improved soil engineering.
Effect of combined oral contraceptives with estrogen identical to natural estrogen on the metabolic profile and body composition in females during the menopausal transition
Authors: Komedina Veronika I. , Yureneva Svetlana V. , Kuznetsov Sergey Yu.
Published: January 2023

Aim. To study the effect of combined oral contraceptives (COC) with estrogen identical to natural estrogen on the metabolic profile and body composition in females during the menopausal transition.
Materials and methods. Females in the menopausal transition who needed contraception were divided into two groups. Group 1 (19 patients) received COCs containing estradiol valerate/dienogest (E2V/DNG) with a dynamic dosing regimen; Group 2 (19 patients) received monophasic COCs containing 17-estradiol/nomegestrol acetate (E2/NOMAC) for 6 months. Blood pressure (BP), parameters of carbohydrate and lipid metabolism, leptin, adiponectin, C-reactive protein, uric acid, and body composition by dual-energy X-ray absorptiometry were assessed initially and after the 6 months of therapy.
Results. No significant changes in weight and body composition after 6 months of COC use were found in both groups. COCs with E2V/DNG had no significant effect on BP and all assessed metabolic parameters. Females taking COCs with E2/NOMAC showed increased fasting glucose of 4.85 (0.43) and 5.30 (0.37) mmol/L (p=0.002), insulin of 4.97 (2.35) and 8.82 (4.67) U/mL (p=0.012), NOMA index of 1.06 (0.54) and 1.88 (0.75); p=0.010 compared to baseline. However, the parameters remained within the reference values.
Conclusion. COCs containing estrogens identical to natural estrogens do not affect body composition and have no significant adverse effect on BP and metabolic parameters in females during the menopausal transition, indicating that the use of these agents is acceptable from the perspective of their metabolic effects in this group of patients.
Endometrial receptivity in women of reproductive age with "thin" and "absolutely thin" endometrium
Authors: Aganezova Natalia V. , Aganezov Sergey S. , Gogichashvili Ksenia E.
Published: January 2023

Aim. To evaluate the expression of steroid receptors (estrogen [ER] and progesterone [PR]) in the endometrium during the implantation window in females with a history of fertility disorders in "thin" and "absolutely thin" endometrium versus healthy females.
Materials and methods. A prospective comparative study was conducted. The study group (n=42) included patients with "thin" endometrium (7 mm M-echo 5 mm at cycle days 1113 according to ultrasound); the comparison group (n=10) included females with "absolutely thin" (5 mm according to ultrasound in the pre-ovulatory days) endometrium (females in both groups had a history of infertility and miscarriage of unclear reasons in the anamnesis); the control group included 16 healthy fertile females. A Pipelle biopsy of the uterine mucosa was performed on day 68 after ovulation, and a peripheral blood sample was obtained to measure the concentration of sex steroids (estradiol [E2] and progesterone [P]). Endometrial samples were examined by histological and immunohistochemical methods (ER, PR expression).
Results. All study participants had an ovulatory cycle of P16.1 nmol/L (day 68 after ovulation) and normal estrogen levels (E2, pmol/L). E2/P was similar in all cohorts (p0.05 for all measures). ER and PR expression in the endometrium similar to those in healthy females was detected in 20% of patients in the study and comparison groups (M-echo = 4.83.1 mm): 21% (9/42) and 20% (2/10), respectively. ER and PR expression in the endometrial glands and ER expression in the endometrial stroma were significantly different (p0.05) from healthy females in 79% (41/52) of patients with "thin" endometrium and 80% (8/10) of patients with "absolutely thin" endometrium. No differences in the ER or PR expression in the endometrium in females with hypoplastic endometrium were found (p0.05).
Conclusion. The M-echo value does not accurately determine endometrial hormonal-receptor abnormalities: 20% of the study participants with hypoplastic endometrium had ER and PR expression comparable to those in healthy females. No differences were found in the expression of endometrial estrogen and progesterone receptors in females with "thin" and "absolutely thin" endometrium.
HPV-associated cervicitis
Authors: Andreeva Margarita V. , Zakharova Kristina  I.
Published: January 2023

Cervical inflammatory disease associated with papillomavirus infection is one of the most common inflammatory diseases of the pelvic organs and plays a role in developing cervical dysplasia and cancer. Over the past 15 years, Russia has seen an increase in the proportion of neglected cervical cancer cases. Currently, the management and treatment strategy for cervicitis associated with human papillomavirus (HPV) and cervical intraepithelial dysplasia ranges from monitoring with HPV testing and cytological control to excision and cervical conization. The immune status determines the course of the papillomavirus infection, which may be transient, latent, or persistent. In most cases (7080%), HPV is eliminated spontaneously. The detection of HPV DNA with clinical and morphological changes indicates a latent course of the disease. The complex use of clinical data and morphological and molecular biological studies results is most promising in identifying early prognostic markers of cervical malignancy. It is the basis for further search for cervical precancer progression pathogenetic markers.
Neural network interpretation techniques for analysis of histological images of breast abnormalities
Authors: Fomina Anna V. , Borbat Artem M. , Karpulevich Evgeny  A. , Naumov Anton Yu.
Published: January 2023

Background. Neural networks are actively used in digital pathology to analyze histological images and support medical decision-making. A common approach is to solve the classification problem, where only class labels are the only model responses. However, one should understand which areas of the image have the most significant impact on the model's response. Machine learning interpretation techniques help solve this problem.
Aim. To study the consistency of different methods of neural network interpretation when classifying histological images of the breast and to obtain an expert assessment of the results of the evaluated methods.
Materials and methods. We performed a preliminary analysis and pre-processing of the existing data set used to train pre-selected neural network models. The existing methods of visualizing the areas of attention of trained models on easy-to-understand data were applied, followed by verification of their correct use. The same neural network models were trained on histological data, and the selected interpretation methods were used to systematize histological images, followed by the evaluation of the results consistency and an expert assessment of the results.
Results. In this paper, several methods of interpreting machine learning are studied using two different neural network architectures and a set of histological images of breast abnormalities. Results of ResNet18 and ViT-B-16 models training on a set of histological images on the test sample: accuracy metric 0.89 and 0.89, ROC_AUC metric 0.99 and 0.96, respectively. The results were also evaluated by an expert using the Label Studio tool. For each pair of images, the expert was asked to select the most appropriate answer ("Yes" or "No") to the question: "The highlighted areas generally correspond to the Malignant class." The "Yes" response rate for the ResNet_Malignant category was 0.56; for ViT_Malignant, it was 1.0.
Conclusion. Interpretability experiments were conducted with two different architectures: the ResNet18 convolutional network and the ViT-B-16 attention-enhanced network. The results of the trained models were visualized using the GradCAM and Attention Rollout methods, respectively. First, experiments were conducted on a simple-to-interpret dataset to ensure they were used correctly. The methods are then applied to the set of histological images. In easy-to-understand images (cat images), the convolutional network is more consistent with human perception; on the contrary, in histological images of breast cancer, ViT-B-16 provided results much more similar to the expert's perception.
Obesity and pregnancy: possible ways to overcome complications and improve reproductive outcomes
Authors: Lapina Irina A. , Dobrokhotova Yulia  Е. , Taranov Vladislav  V. , Sorokin Yury  A. , Chirvon Tatiana  G. , Malakhova Anastasiya  A.
Published: January 2023

Introduction. Obesity, due to its high prevalence and relevance, can be considered an epidemic of modern society. Obesity-related microcirculatory vascular disease and chronic inflammation with endothelial dysfunction are associated with adverse effects on reproductive potential. Sulodexide reduces the risk of hemostatic complications in patients planning pregnancy due to its polypotent effect, which is especially important in metabolic disorders and comorbidities. Therefore, it is promising to assess the effectiveness of integrated management of obese patients as part of pregnancy planning.
Aim. To modify the complex treatment of obesity in patients planning pregnancy to reduce the risk of reproductive losses and gestational complications.
Materials and methods. The prospective analysis included 92 patients with grade 1 obesity. According to the clinical protocols and guidelines of the Reproductive Health Professional Medical Association, 46 patients in the control group (group 1) were prescribed treatment to reduce the body mass index, including lifestyle correction, folic acid, and vitamin D. Patients in the comparison group (Group 2, n=46) also received endotheliotropic agent sulodexide. The treatment efficacy was analyzed based on the frequency of pregnancy, the change of laboratory markers of endothelial dysfunction, the incidence of gestational complications, and reproductive losses.
Results. The study showed that in comparison group patients, the frequency of pregnancy (58.7% of cases in Group 1, 71.7% in Group 1), favorable course of the first trimester (39.1% in Group 1, 63.0% in Group 2), and delivery at term (30.4% in Group 1, 56.5% in Group 2) were higher compared to the control group. There was also a more significant decrease in the body mass index and endothelial dysfunction factors (homocysteine level in group 1 before treatment was 172.4 mol/L, and 141.8 mol/L after treatment; 191.7 mol/L before treatment and 91.4 mol/L after treatment in Group 2, respectively) in patients receiving complex treatment with sulodexide. Analysis of the pregnancy course showed a lower risk of gestational diabetes (33.3% in Group 1 and 13.8% in Group 2).
Conclusion. Treatment of obesity in patients planning pregnancy requires a complex effect aimed at correcting lifestyle, reducing body weight, restoring the endothelial layer, and reducing the severity of chronic inflammation, thus improving reproductive outcomes and minimizing the risk of gestational complications.
EFFECT OF DIFFERENT BIOCHAR CONCENTRATION ON THE GROWTH OF THREE AGRICULTURAL PLANTS IN AFGHANISTAN
Authors: Hallim Majidi Abdul
Published: January 2023

The present research was conducted in the laboratory of Badakhshan University, Afghanistan. The study was carried out for 40 days in 2021, to document the effect of biochar on the growth of three important agricultural plant species: radish, lettuce and spinach. The biochar was produced from the biomass of Oak tree under oxygen less condition. The study includes assessment of Petri plate bioassay and pot scale experiment to understand the effect of biochar under saline and non-saline conditions in order to mitigate the problem of salinity. Application of biochar has significantly increased the seed germination for all the seeds. The maximum seed germination was observed for radish > lettuce > spinach. NaCl has reduced the percentage of seed germination but a little increase was observed in case of radish as compared to lettuce and spinach. However, application of biochar has significantly increased its growth as compared to control plant. Both shoot and root of all three studied plants were increased with increase in BC concentrations. The maximum length of root was observed for radish > lettuce > spinach whereas for shoot it was lettuce > radish > spinach. At the same time application of 5 % biochar helped to improve the growth of both radish shoot and root. Lettuce was found sensitive to saline condition and application of biochar does not significantly improve their morphometric parameters. Spinach could be considered as moderately saline resistant species whose biomass can be improved by supplementing with biochar.