bluuebunny/crossref_metadata_2025 huggingface dataset:
Incorporation of Computer Vision and Metaverse Analysis Using UAV Communications for Healthcare Applications
Authors: Madavan Mukunth , Kumar R. Akshay , Ramakrishnan Akshay Bhuvaneswari , R. Manikandan , Magesh S.
Published: August 2024

The integration of computer vision, unmanned aerial vehicles (UAVs), and metaverse analysis has potential to transform healthcare and offers solutions to geographical challenges. Emphasizing real-world applications, it details how computer vision aids in real-time patient monitoring and disease detection, while the metaverse enables immersive medical simulations and remote patient monitoring. Unmanned aerial vehicles help break the geographical barriers and give people access to healthcare services. The synergy between computer vision and metaverse analysis facilitates revolutionary data analysis and has multiple applications. Augmented reality (AR) and virtual reality (VR) tools enhance user engagement, enabling remote patient monitoring and medical simulations. The integration of metaverse analysis with UAVs introduces applications such as remote operation, telemedicine, propelling healthcare into a new era.
Challenges With the Blockchain-Powered Healthcare Secure System
Authors: Sumitra P. , Sathiya M. , Gayathiri A. , Sathya G. , Sabitha S. , Ghinea George
Published: August 2024

The expansion of the internet and the growing use of technology in the healthcare system have helped doctors monitor their patients remotely through the use of real-time smart health devices. In spite of this sophisticated system, there are many concerns regarding the sensitive data of the patients being exposed to the world by hackers. Thus, the shortcomings of the healthcare framework can be resolved by leveraging blockchain tools. The mechanism of the blockchain health system works in such a way that an id is assigned to a patient health record, and they can give access to view their health records to the specific health provider of their choice. Eventually, by using this mechanism, the patient's health record is secured from the hackers. Thus, this chapter deals with data privacy of the patient's health, research objectives, issues, and challenges that can be easily understandable and helpful for beginners in their research progress.
Advancements in Cognitive Radio Networks
Authors: Yamini B. , Beslin Pajila P. J. , Anish T. P , Gracelin Sheena B , Dinesh M. G. , Nalini M. , Siva Subramanian R.
Published: August 2024

Cognitive radio networks (CRNs) revolutionise wireless communications by providing dynamic spectrum access and management to overcome static spectrum allocation. This overview explores CRNs from fundamentals to cutting-edge protocols and applications. It addresses cognitive radio theory, hardware, networking, and difficulties for academics and practitioners. Starting with CRNs' history and motivation, it describes research scope and qualities. The research examines dynamic spectrum access, waveform design, and resource allocation. Detailed networking protocol and standard analysis covers medium access control and interference management. Additionally, cooperative communications and database-driven CRNs are considered. To solve spectrum sharing economics and regulations, next-gen technologies, energy-efficient designs, creative applications, and business models are explored. Examining flexible CRN feature machine learning methods. The analysis concludes with future trends and guides cognitive radio network research and innovation.
Predictive Analysis of Modulation Classification and Adaptive Modulator for Next Generation Networks
Authors: Bilal Rabia , Khan Bilal Muhammad
Published: August 2024

Cognitive radios are used for dynamic spectrum management and interference identification. Automatic modulation classification is used for identification of modulation scheme of received signal. Modulated signals have a Cyclostationary property, through which they are identified and then further processed. Cyclostationary feature detection method detects the Cyclostationary features and then identifies the modulation type. The cyclic frequency domain profile that is extracted from spectral correlation function is used for the classification of modulation. Each modulation scheme has a different cyclic frequency domain profile.
Information Granule, Modeling, and Application From the Perspective of Granular Computing
Authors: Kong Qingzhao , Wang Wanting , Yan Conghao
Published: August 2024

By granulating the data in the information table and using information granules to analyze the data, the efficiency of data mining can be greatly improved. In this chapter, firstly, in order to better understand information granules, many numerical characteristics related to information granules are deeply discussed. Then, due to different learning rules, various granular structures can be induced. In addition, with the help of these granular structures, corresponding data mining models are constructed according to the needs of learning tasks. Specifically, based on the idea of three-way decision, a novel granular computing model is developed. What's more, the developed model can be successfully applied in network security.
Multi-Granulation-Based Optimal Scale Selection in Multi-Scale Information Systems
Authors: Zhan Tao
Published: August 2024

This chapter establishes belief and plausibility functions within the context of multigranulation, delving into the structures of belief and plausibility. The focus extends to the examination of multigranulation rough sets within multi-scale information systems. Subsequently, to determine the optimal level within the multigranulation rough set, a method for optimal scale selection is introduced. This method caters to diverse requirements in optimistic and pessimistic multigranulation within the multi-scale information system. In-depth analyses of the characteristics of optimistic and pessimistic multigranulation optimal scale selection for multi-scale information systems are conducted separately, revealing intrinsic connections between distinct optimal scale selection methodologies.
Unusual response with tyrosine kinase inhibitor in small-cell lung cancer
Authors: Aashita  , Mishra Hemendra , Suri Kapil , Yadav Vikas , Thakur Pragyat
Published: August 2024

The discovery of targetable mutations in non-small-cell lung cancer (NSCLC) has opened up a plethora of therapeutic options. Epidermal growth factor receptor (EGFR) mutations are found in 10%–20% of NSCLC; however, it is extremely rare in small-cell lung cancer (SCLC), and the efficacy of EGFR tyrosine kinase inhibitors (TKIs) in SCLC is unclear. Here, we describe the case of a 57-year-old nonsmoker lady who was diagnosed with metastatic SCLC. She received multiple lines of palliative chemotherapy. She was deemed unfit for further chemotherapy and immunotherapy and was started on tablet erlotinib empirically. On follow-up imaging with positron emission tomography-computed tomography, she had a partial response and has currently on erlotinib for 2.5 years without disease progression. Although cases with transformation of EGFR-mutated NSCLC to SCLC have been observed, de novo EGFR mutation in SCLC is infrequent. It has been observed that de novo EGFR mutation in SCLC is associated with females, non-smokers, and patients in the eastern part of the world. The current guidelines do not recommend molecular testing for EGFR mutations in SCLC. We described a case of SCLC who had a response to TKI and such cases warrant an answer to whether EGFR mutation testing should be recommended in nonsmoker, females with SCLC, or for them who have failed the first line of chemotherapy.
A study of the assessment of pathological response to neoadjuvant chemotherapy in patients with breast cancer
Authors: Mallige Supriya , Ananthamurthy Anuradha , Vellaisamy Gnanapriya
Published: August 2024

BACKGROUND:

Neoadjuvant chemotherapy therapy ( NACT) has emerged as an integrated therapeutic approach to treat locally advanced breast cancer in order to down stage the tumour and to assess tumour response to chemotherapy. The aims of this study were to estimate the incidence of complete and partial pathological response in patients undergoing NACT for breast cancer and to evaluate the clinico pathological parameters associated with pathological response.

MATERIALS AND METHODS:

The study included breast cancer specimens from patients who had received NACT. The pathological response to NACT was assessed by the AJCC protocol and the morphological features associated with NACT were recorded. The clinicopathological parameters associated with complete pathological response were also studied. The association between the clinicopathological paramaters and pathological response was studies using Chi square and Fisher exact tests.

RESULTS:

There were a total of 50 women who underwent surgery for breast cancer following NACT. The mean age was 56.5 years. The majority (59.1%) belonged to stage IIIB followed by Stage III A ( 30.6%). 73.4% of cases showed clinical partial response, 14.2 % showed no response and 12.2 percent showed Pathological Complete Response (pCR). ER and PR negative and Her 2 positive status were the parameters significantly associated with pCR.

CONCLUSIONS:

Pathological evaluation is the most reliable method to assess response to NACT in breast cancer patients which may further influence management decisions. This study showed a much lower frequency of pCR when compared to other Indian studies. It is recommended that all patients who are treated with NACT undergo prior core needle biopsy with hormone receptor and Her 2 testing as they may have a bearing on pCR.
Reactivation of Hepatitis B Virus among Malignancy Patients Undergoing Chemotherapy: A Prospective Cohort Study
Authors: Sethia Mohit , Jain Rahul , Singh Vani , Singh Santosh , Mahajan Saurabh , Jain Harshul , Yadav Jyoti , Yadav A. K.
Published: August 2024

Introduction:

Reactivation of hepatitis B virus (HBV) can occur in patients receiving short-term chemotherapy, long-term immunosuppressive therapy, or disease-modifying antirheumatic agents for rheumatological diseases and is more common in hepatitis B surface antigen-positive patients. However, there is a lack of data for reactivation among malignant patients undergoing chemotherapy in resolved HBV patients.

Methodology:

A prospective cohort study of 200 oncological patients on chemotherapy was conducted for the reactivation of the HBV for a year. Patients underwent a thorough physical examination; baseline assessment and biochemical test and test were repeated at each follow-up.

Results:

The majority were females and in the 40–60-year age group. Age and serum albumin levels were significantly different (P < 0.05) among the reactivated versus the nonreactivated groups. Hepatitis B reactivation was seen in 14 (7%) patients with a maximum in the rituximab therapy group (11.26%). There was no statistically significant difference in baseline ALT levels between patients who experienced reactivation and those who did not.

Conclusion:

In the present study population, 7% had hepatitis B reactivation. The present study identifies old age, low serum albumin, and rituximab chemotherapy as significant risk factors for reactivation. Prophylactic antiviral therapy seems to be effective as no reactivation has occurred in this group.
Human Leukocyte Antigen-DR and Cluster Designation 34: Double-negative Acute Myeloid Leukemias – Our Experience in Clinical Setting
Authors: Tripathi Preeti , Khera Sanjeev , Kumar Rajiv , Kapoor Rajan , Kapoor Umesh , Chawlar Naveen
Published: August 2024

Introduction:

Dual negativity for cluster designation (CD) 34 and human leukocyte antigen (HLA)-DR antigen in leukemia panel is an important finding in clinical practice. The combination of this finding though seen classically in acute promyelocytic leukemia (APL) is not specific to it but can be seen in many other myeloid leukemias like the ones associated with nucleophosmin 1 (NPM1) or FMS-related tyrosine kinase 3 gene-internal tandem duplication (FLT3-ITD) abnormalities. It is important to identify APL from non-APL leukemia as treatment and prognosis vary.

Aims and Objectives:

We analyzed CD 34 and HLA-DR dual-negative acute myeloid leukemia (AML) cases presented to us over 2.5 years (26 cases) and segregated them into APL and non-APL groups to study their morphological/flow cytometric and cytogenetic profile and correlation with treatment response.

Materials and Methods:

It was a prospective study including all newly diagnosed AMLs showing CD 34 and HLA-DR dual negativity in flow cytometry profile. Cases in which complete information/cytogenetics/molecular profile were not available, were excluded from the study. The patients were followed up till the end of induction to look for morphological response to induction therapy. The clinical and treatment records were pulled out from the patient database after ethical committee clearance.

Results:

A total of 139 new AML cases were encountered during the study period out of which 28 (20%) were found to be dual negative for CD34 and HLA-DR. The non-APL group showed higher mean age, TLC at baseline, variable morphology, and more number of aberrant expression on flow cytometry profile. No significant difference was noted in terms of gender, presence of hepatosplenomegaly, DIC as complication, or percentage of blasts/blasts equivalent at baseline. Our study found that while all APL patients had PML-RARA, the associated molecular abnormalities were much lesser as compared to the non-APL group which showed a variety of abnormalities such as NPM1, FLT3, RAS mutation, and mutations involving epigenetic modifiers. The response rate to induction therapy was significantly lower in the non-APL group as compared to the APL group.

Conclusion:

The non-APL myeloid leukemia which is dual negative is commonly found to be associated with cup-shaped morphology, NPM, or FLT3-ITD mutation along with other abnormalities. These patients were older in age, showed higher TLC and higher blast counts, associated with poorer response to induction therapy as compared to the APL group.
Case-based Learning in Obstetric Hemorrhagic Emergencies
Authors: Chawla Sushil , Sharma Rajesh
Published: August 2024

Background:

Our institution’s obstetrics and gynecology course for final-year students traditionally relied solely on theoretical lectures. To bridge the gap between theory and real-world scenarios, we implemented case-based learning (CBL) that incorporates case discussions and other practical activities. This study aimed to assess the impact of these changes on students’ performance and perceptions of their learning experience.

Materials and Methods:

CBL was introduced for the teaching of a final year students about atonic postpartum hemorrhage. Comparisons were made with the two groups of the same batch. The students were assessed for the content retention and analytical skills. Students and faculty members were asked to rate their satisfaction with the teaching program.

Results:

The mean pretest score for the MCQs improved from 5 to 7.52–7.89, showing an improved content retention in both the groups. The mean score for analytical skills in CBL group was 7.96 as compared to 4.5 in the lecture group.

Conclusion:

CBL is helpful in improving the analytical skills of the undergraduate medical students.
Pregnancy and COVID—Complications and its Challenges: A Case Series from a Tertiary Care Center in the Northeastern Part of India
Authors: Khanikar Reshu G. , Baruah Rakhee , Choudhury Kalpana , Lahkar Brajendra , Sharma Chandana , Baishya Manas Jyoti
Published: August 2024

The objective was to describe the course of management of all the coronavirus disease 2019 (COVID-19)-positive pregnant women, admitted to a 150-bedded tertiary care center in Guwahati, Assam, from March 01, 2021, till June 15, 2021. We collected a case series of 13 COVID-19-positive pregnant women, mostly in their second and third trimesters, admitted to our center between March 01, 2021, and June 15, 2021. All of the cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection were confirmed by a positive result on real-time reverse transcriptase-polymerase chain reaction (RT-PCR) tests. We aimed to show the course of management and maternal outcomes in these cases. The Results show that among the 13 infected pregnant women, three presented with severe SARS-CoV-2 pneumonia and were treated in the intensive care unit (ICU) and the rest were treated in wards as the mild category and discharged successfully. Two among them required invasive mechanical ventilation (IMV), and one was managed on non-invasive ventilation (NIV). Of the two mechanically ventilated patients, one succumbed to the illness and the other patient was successfully weaned in 5 days and shifted out after 15 days of the ICU stay. The third patient was on NIV support for 7 days, weaned off to low-flow oxygen therapy via face mask/ nasal prongs, and shifted out after 17 days of the ICU stay. Data on pregnant women with coronavirus infection are scarce and contradictory as the effect of SARS-CoV-2 on pregnancy is not clear. It is highly important to systemically investigate the clinical characteristics and outcomes of pregnant women with COVID-19 to provide strong guidelines for prevention, treatment, and management.
Trichoscopic findings in patients with patchy alopecia and its comparison with histopathological diagnosis
Authors: Unnikrishnan Indukrishnan Manikkasseril , Mathew Rani
Published: August 2024

Introduction:

Loss of hair is one of the most common complaints that baffle dermatologists. Diagnosis of patchy alopecia is challenging because of overlapping clinical and histopathological features. Trichoscopy is an easy diagnostic modality which also helps demonstrate the problem to the patient.

Objective:

To study the trichoscopy and histopathology in patchy alopecia scalp and to look for any correlation.

Materials and Methods:

This was a cross-sectional study for 18 months from January 2017 after obtaining permission from the institutional ethics committee.

Results:

Trichoscopic and histopathological concordance in patchy alopecia was 73.77% in our study. The most common trichoscopic findings observed were black dots, perifollicular pigmentation, and white patches in alopecia areata, lichen planus pigmentosus, and discoid lupus erythematosus, respectively.

Conclusion:

Trichoscopy is a useful tool in the diagnosis of patchy alopecia.
Novel genes involved in vascular dysfunction of the middle temporal gyrus in Alzheimer’s disease: transcriptomics combined with machine learning analysis
Authors: Wang Meiling , He Aojie , Kang Yubing , Wang Zhaojun , He Yahui , Lim Kahleong , Zhang Chengwu , Lu Li
Published: August 2024

JOURNAL/nrgr/04.03/01300535-202512000-00030/figure1/v/2025-01-31T122243Z/r/image-tiff

Studies have shown that vascular dysfunction is closely related to the pathogenesis of Alzheimer’s disease. The middle temporal gyrus region of the brain is susceptible to pronounced impairment in Alzheimer’s disease. Identification of the molecules involved in vascular aberrance of the middle temporal gyrus would support elucidation of the mechanisms underlying Alzheimer’s disease and discovery of novel targets for intervention. We carried out single-cell transcriptomic analysis of the middle temporal gyrus in the brains of patients with Alzheimer’s disease and healthy controls, revealing obvious changes in vascular function. CellChat analysis of intercellular communication in the middle temporal gyrus showed that the number of cell interactions in this region was decreased in Alzheimer’s disease patients, with altered intercellular communication of endothelial cells and pericytes being the most prominent. Differentially expressed genes were also identified. Using the CellChat results, AUCell evaluation of the pathway activity of specific cells showed that the obvious changes in vascular function in the middle temporal gyrus in Alzheimer’s disease were directly related to changes in the vascular endothelial growth factor (VEGF)A–VEGF receptor (VEGFR) 2 pathway. AUCell analysis identified subtypes of endothelial cells and pericytes directly related to VEGFA–VEGFR2 pathway activity. Two subtypes of middle temporal gyrus cells showed significant alteration in AD: endothelial cells with high expression of Erb-B2 receptor tyrosine kinase 4 (ERBB4high) and pericytes with high expression of angiopoietin-like 4 (ANGPTL4high). Finally, combining bulk RNA sequencing data and two machine learning algorithms (least absolute shrinkage and selection operator and random forest), four characteristic Alzheimer’s disease feature genes were identified: somatostatin (SST), protein tyrosine phosphatase non-receptor type 3 (PTPN3), glutinase (GL3), and tropomyosin 3 (PTM3). These genes were downregulated in the middle temporal gyrus of patients with Alzheimer’s disease and may be used to target the VEGF pathway. Alzheimer’s disease mouse models demonstrated consistent altered expression of these genes in the middle temporal gyrus. In conclusion, this study detected changes in intercellular communication between endothelial cells and pericytes in the middle temporal gyrus and identified four novel feature genes related to middle temporal gyrus and vascular functioning in patients with Alzheimer’s disease. These findings contribute to a deeper understanding of the molecular mechanisms underlying Alzheimer’s disease and present novel treatment targets.
Machine learning identifies key cells and therapeutic targets during ferroptosis after spinal cord injury
Authors: Lv Yigang , Li Zhen , Shi Lusen , Jian Huan , Yang Fan , Qiu Jichuan , Li Chao , Xiao Peng , Ruan Wendong , Li Hao , Li Xueying , Feng Shiqing , Zhou Hengxing
Published: August 2024

Ferroptosis, a type of cell death that mainly involves iron metabolism imbalance and lipid peroxidation, is strongly correlated with the phagocytic response caused by bleeding after spinal cord injury. Thus, in this study, bulk RNA sequencing data (GSE47681 and GSE5296) and single-cell RNA sequencing data (GSE162610) were acquired from gene expression databases. We then conducted differential analysis and immune infiltration analysis. Atf3 and Piezo1 were identified as key ferroptosis genes through random forest and least absolute shrinkage and selection operator algorithms. Further analysis of single-cell RNA sequencing data revealed a close relationship between ferroptosis and cell types such as macrophages/microglia and their intrinsic state transition processes. Differences in transcription factor regulation and intercellular communication networks were found in ferroptosis-related cells, confirming the high expression of Atf3 and Piezo1 in these cells. Molecular docking analysis confirmed that the proteins encoded by these genes can bind cycloheximide. In a mouse model of T8 spinal cord injury, low-dose cycloheximide treatment was found to improve neurological function, decrease levels of the pro-inflammatory cytokine inducible nitric oxide synthase, and increase levels of the anti-inflammatory cytokine arginase 1. Correspondingly, the expression of the ferroptosis-related gene Gpx4 increased in macrophages/microglia, while the expression of Acsl4 decreased. Our findings reveal the important role of ferroptosis in the treatment of spinal cord injury, identify the key cell types and genes involved in ferroptosis after spinal cord injury, and validate the efficacy of potential drug therapies, pointing to new directions in the treatment of spinal cord injury.
Serologically Confirmed Human Leptospirosis in Colombia, 2015–2020
Authors: Parra-Barrera Eliana L. , Bello-Piruccini Solmara , Rodríguez Karina , Duarte-Valderrama Carolina , Torres Marisa , Undurraga Eduardo A.
Published: August 2024

Leptospirosis, a bacterial infection transmitted through contact with infected animals or contaminated water sources, imposes a substantial health burden in Colombia. Since 2007, the National Institute of Health (INS) has mandated the notification and confirmation of all suspected leptospirosis cases. This passive surveillance program employs the microscopic agglutination test (MAT) on serum samples to ascertain confirmed cases of leptospirosis infection. However, the absence of a robust surveillance system has hindered our comprehensive understanding of the morbidity, mortality, geographical distribution, species/serovars, and strains responsible for severe disease. Our study aimed to provide an epidemiological overview of MAT-confirmed human leptospirosis cases reported over 6 years (2015–2020) in Colombia. In addition, we offer insights into the status of leptospirosis in the country, focusing on risk factors and proposing potential improvements for diagnosis and disease management. During the 6-year surveillance period, the laboratory at the INS received 3,535 serum samples from suspected human leptospirosis cases, with 880 (25%) confirmed through MAT. The incidence of leptospirosis was calculated at 1.9 cases per 100,000 people, with a higher prevalence among men (82.1%). Furthermore, 54 (6.1%) deaths were confirmed as leptospirosis, and cases were documented across nearly all regions of Colombia. Our findings emphasize the urgent need to strengthen leptospirosis laboratory surveillance, implement effective prevention measures, and enhance diagnostic capabilities in Colombia. The analysis conducted in this study provides the groundwork for estimating the impact of leptospirosis and raises awareness of its significance in public health.
Integrated Histological and Molecular Analysis of Filarial Species and Associated Wolbachia Endosymbionts in Human Filariasis Cases Presenting Atypically in Thailand
Authors: Sarasombath Patsharaporn T. , Sitthinamsuwan Panitta , Wijit Sirirat , Panyasu Kedsara , Roongruanchai Kosol , Silpa-Archa Sukhum , Suwansirikul Matya , Chortrakarnkij Peerasak , Ruenchit Pichet , Preativatanyou Kanok , Wongkamchai Sirichit
Published: August 2024

Atypical presentations of filariasis have posed diagnostic challenges due to the complexity of identifying the causative species and the difficulties in both diagnosis and treatment. In this study, we present the integrative histological and molecular analysis of seven atypical filariasis cases observed in regions of nonendemicity of Thailand. All filariasis cases were initially diagnosed based on histological findings. To confirm the causative species, molecular characterization based on both filarial mitochondrial (mt 12S rRNA and COI genes) and nuclear ITS1 markers was performed, together with the identification of associated Wolbachia bacterial endosymbionts. Among the cases studied, Brugia pahangi (N = 3), Brugia malayi (N = 1), Dirofilaria sp. “hongkongensis” (N = 2), and a suspected novel filarial species genetically related to Pelecitus copsychi (N = 1) were identified. By targeting the 16S rRNA gene, Wolbachia was also molecularly amplified in two cases of infection with Dirofilaria sp. “hongkongensis.” Phylogenetic analysis further revealed that the detected Wolbachia could be classified into supergroups C and F, indicating the high genetic diversity of this endosymbiont in Dirofilaria sp. “hongkongensis.” Furthermore, this study demonstrates the consistency between histological findings and species identification based on mitochondrial loci rather than on the nuclear ITS1. This suggests the utility of mitochondrial markers, particularly COI, as a highly sensitive and reliable diagnostic tool for the detection and differentiation of filarial species in clinical specimens. Precise identification of the causative species will facilitate accurate diagnosis and treatment and is also essential for the development of epidemiological and preventive strategies for filariasis.
Press Articles from “Gazeta Polska w Brazylii” as a Source of Information about Brazilian Polonia’s Interests in the Security of the Second Republic of Poland in July and August 1939 – Selected Issues
Authors: Landmann Tomasz
Published: August 2024

The article aims to present an outline and analysis of the topics presented in the July and August 1939 issue of “Gazeta Polska w Brazylii” (“Polish Newspaper in Brazil”). These concerned informing the Brazilian Polish community about matters and interests crucial to the Polish state’s security.

The article analyses all the issues of “Gazeta Polska w Brazylii” of July and August 1939, the available scientific literature, and other printed sources.

It has been shown that “Gazeta Polska w Brazylii” was the leading periodical informing the Brazilian Polonia about matters important to the Polish state’s interests and security. On the eve of the outbreak of World War II, the dominant issues of interest to the Polish community in Brazil included the evaluation of the Brazilian government, Hitler and the Third Reich, and German actions towards the local population in the areas taken over by the German state in 1938 and 1939. The issue of the Free City of Danzig and German militarism in the region, which threatened the interests of the Second Republic and Polish citizens’ position, was also significant.
Improving Patient Awareness and Compliance with Telephone Follow-up Calls Post Visit
Authors:   , Kutti Ajibola
Published: August 2024

Practice Problem: In a high-volume clinic without current follow up practices post visit, a telephone follow-up (TFU) intervention was implemented within three days of patient outpatient appointments. PICOT: The PICOT question that guided this project was: In adult patients in a high-volume clinic (P), does the implementation of telephone follow-up calls by nurses (I) compared to current practices (C) improve patient compliance and post-office follow-up visits (O) over 10-weeks (T)? Evidence: The literature provided recommendations and evidence that supported the effectiveness of following up with patients within three days of leaving the healthcare clinic. TFU’s are a cost-effective intervention that provides opportunities for patient education, improvements in patient compliance and reduction of adverse events. Intervention: Nurses utilized a TFU checklist where they assessed patient compliance and awareness with individualized care plan, required lab work, medication, diet and exercise regimen prior to their follow up visit. Outcome: The Fisher’s exact test was not significant based at an alpha value of .05, OR = 0.00, p = 1.00. However, clinical significance was found because of the increase in patients attending follow-up clinic visits. Conclusion: The implementation of TFU within three days of patient outpatient visit resulted in 83% of patient’s verbalizing awareness of their individual care plan and 88% of patients attending their follow up visit.
A historical trajectory of Financial Education: from OEEC to the new ENEF
Authors: Silva Priscila de Oliveira e , Mazzi Lucas Carato
Published: August 2024

This paper discusses the relevant historical aspects of Financial Education. The aim is to contribute to a broad understanding of how the subject has been built up, changed and become an everyday topic. We start from the creation of the Organisation for European Economic Co-operation (OEEC), through the Organisation for Economic Cooperation and Development (OECD), which developed Financial Education, until we arrive in Brazil, with the Estratégia Nacional de Educação Financeira (ENEF — National Strategy for Financial Education), in 2010, updated in 2020. The historical trajectory of the OECD and ENEF proposals shows a market approach to Financial Education. Over the years, in the context of education and Mathematics Education, discussions have matured, resulting in a Financial Education that questions the neoliberal system and seeks social transformation.
ROLE OF DUSHI VISHA IN SKIN DISEASES: A REVIEW
Authors: Chaudhari Hinal , Lal Prajapati Munna , Sason Rajveer
Published: August 2024

Background: Dushi Visha is one of the unique Agada Tantra concepts in Ayurveda. Visha is a chemical that vitiates all seven Dhatus and can also be fatal when ingested. Dushi Visha is the term used to describe any poison
that comes from Sthavara or Jangama sources, or Kritrima Visha that is kept in the body after being partially expelled or that has temporarily undergone detoxification using anti-poisonous medications, etc. Aim: This study
aims to understand the skin diseases caused by Dushi Visha. Material and methods: Reviewed from various
Ayurvedic literature, websites, and relevant journals. Result: According to all Acharya, Dushi Visha is a slowacting poison that builds up in our bodies. Because of its low potency, it does not immediately induce illness; instead, chronic disease is brought on by repeated exposure to the toxin. Such collected Visha gives rise to numerous skin illnesses and vitiates Dhatu, especially Rakta Dhatu. Detoxification is the first treatment for Dushi Visha,
which Dushivishari Agada Paana then follows. Discussion and conclusion: Skin illnesses are becoming increasingly significant today. The essential elements of life—air, food, and water—are all contaminated. Thus, Dushi
Visha can be determined by considering aspects like Viruddhahara, Ahitaahara, cold beverages, specific medications, cosmetics, pesticides, metals, minerals, pollutants, etc. The body retains these cumulative toxins and exhibits many dermatological signs.
ECONOMÍA SUMERGIDA Y EMPLEO IRREGULAR. IMPACTO EN ANDALUCÍA. CAUSAS. CONSECUENCIAS. POSIBILIDADES DE REACCIÓN
Authors: ÁLVAREZ MARTÍN JUAN ANTONIO
Published: August 2024

El presente trabajo pretende reflexionar sobre los problemas derivados de la economía sumergida y el empleo irregular, la dificultad que existe para cuantificarlos, sus causas y consecuencias, las peculiaridades que presentan en Andalucía, y apunta alguna contribución a las posibles vías de actuación.
LIBERACIÓN DE EXPROPIACIONES URBANÍSTICAS. SU REGULACIÓN AUTONÓMICA ANDALUZA
Authors: FERNÁNDEZ-FIGUEROA GUERRERO FERNANDO
Published: August 2024

Se trata de exponer las expropiaciones por razón de urbanismo, la positivación de la institución de la "liberación de expropiaciones urbanísticas" en el ordenamiento jurídico-urbanístico español, y la parca regulación de la liberación de expropiaciones urbanísticas en la normativa urbanística de Andalucía.
EL PROCEDIMIENTO PARA EL RECONOCIMIENTO DE LA SITUACIÓN DE DEPENDENCIA: PERSPECTIVAS DE DESARROLLO Y DE FUTURO EN EL MARCO DEL ESTADO DE BIENESTAR SOCIAL EN LA COMUNIDAD AUTÓNOMA ANDALUZA
Authors: PÉREZ CASTILLO RAFAEL , OLMEDO AREAL JOSÉ MANUEL
Published: August 2024

El objeto de este trabajo no es más que, desde una perspectiva práctica, la aplicación de la LAAD, así como de unas propuestas de mejoras en el devenir de la misma.
PROTECCIÓN JURÍDICA DEL PATRIMONIO CULTURAL
Authors: RODRÍGUEZ LEÓN LUIS CARLOS
Published: August 2024

Esta obra presenta una serie de ponencias procedentes de un Curso en la Escuela de Verano de la Universidad Pablo de Olavide de Sevilla. Dichos escritos han sido elaborados por profesionales de reconocida solvencia en el ámbito del conocimiento jurídico-cultural, con la idea de debatir y contribuir a mejorar el conocimiento y la protección del Patrimonio Histórico.
Prevalência e fatores associados ao Transtorno de Estresse Pós-Traumático (TEPT) em trabalhadores de emergência: uma revisão sistemática da literatura
Authors: Victor Letícia Silva , Santos Juliana Coelho Costa dos , Costa Bárbara Rodrigues , Gonçalves Letícia Santana Ferreira
Published: August 2024

O Transtorno de Estresse Pós-Traumático (TEPT) é um transtorno mental que pode ocorrer após a exposição a eventos traumáticos e afeta significativamente a vida dos indivíduos. Profissionais de emergência, como médicos, bombeiros e socorristas, estão frequentemente expostos a situações de alto estresse e risco, o que os torna particularmente vulneráveis ao TEPT. Este estudo tem como objetivo revisar a literatura sobre a prevalência e os fatores associados ao TEPT em trabalhadores de emergência. Foram selecionados artigos das bases de dados PubMed, LILACS, UpToDate e Cochrane Library, publicados nos últimos cinco anos. Os resultados indicam uma prevalência elevada de TEPT entre esses profissionais, destacando a importância de intervenções direcionadas para o manejo do estresse e apoio psicológico. A revisão aponta para a necessidade de estratégias eficazes de enfrentamento e a implementação de políticas de saúde mental no ambiente de trabalho.
Episódios maníacos para pacientes com Transtorno Bipolar em remissão: uma revisão da literatura
Authors: Seixas Carlos Henrique Aires Magalhães , Wladimirski Piettra Salzano , Souza Lorena Igawa , Martins Júnior Carlos Roberto de Almeida , Rocha Fernanda Rodrigues
Published: August 2024

Esta revisão objetiva analisar e caracterizar aspectos inerentes à ocorrência de episódios maníacos em pacientes durante a fase de remissão do Transtorno Afetivo Bipolar (TAB), além de ponderar seus impactos e consequências tanto na vivência quanto no prognóstico do transtorno. O TAB é um transtorno de humor complexo e multifatorial cuja expressão clínica se traduz em alterações significativas do humor, alternando entre episódios de euforia (mania e hipomania) e depressão, intercalados por períodos de remissão. A mania e a hipomania são caracterizadas pelos mesmos componentes, diferenciando-se em intensidade e duração: a mania, com sintomas mais duradouros e intensos, define o TAB tipo 1, enquanto a hipomania, com sintomas mais breves e menos intensos, define o TAB tipo 2. Embora ambas tragam prejuízos clínicos e sociais ao paciente, a mania se destaca por ser potencialmente incapacitante, através de euforia, grande impulsividade, irritabilidade, hipersexualização, desorganização de pensamentos e até delírios, podendo desencadear quadros psicóticos. O diagnóstico precoce e o tratamento dos episódios agudos melhoram significativamente o prognóstico ao reduzir a intensidade e a frequência das oscilações do humor.
Prevalência de insônia em trabalhadores em turnos: uma revisão sistemática
Authors: Meneses Lara Neiva , Reis Klícia Martins , Silva Camila Rafaela Dressel da , Guinazi Milena Freire , Pasa Laura Fogaça
Published: August 2024

A prevalência de distúrbios do sono em trabalhadores de turnos tem se mostrado crescente nos últimos anos, tendo a insônia como a principal integrante desse grupo. Com o aumento da prevalência, houve um incremento na preocupação com as possíveis sequelas desses distúrbios, impactando negativamente a saúde e o desempenho no trabalho. Esta revisão sistemática visa sintetizar e avaliar os estudos disponíveis que abordam a prevalência da insônia em trabalhadores de turnos, como turnos noturnos e rotativos em diversas profissões. Metodologia: A pesquisa foi conduzida mediante busca em bases de dados científicas (PubMed, SciELO, Web of Science e Scopus), utilizando termos específicos ("insônia" e "trabalho em turnos") e filtros de qualidade (publicações em português, inglês ou espanhol entre 2004 e 2024). Foram incluídos estudos que avaliaram a prevalência da insônia em trabalhadores de turnos, seguindo critérios rígidos de elegibilidade para garantir a confiabilidade dos resultados. Resultados: Os resultados revelaram uma prevalência de insônia entre os trabalhadores de turnos, com variações dependendo do tipo de turno, duração do trabalho noturno, idade, sexo, e fatores demográficos, ocupacionais e sociais. A desregulação do ciclo circadiano, estresse, exposição à luz artificial durante a noite e piores condições de trabalho foram importantes determinantes na presença de insônia. Constatou-se que a insônia contribui para diversas consequências, como aumento do risco de acidentes de trabalho, distúrbios do sono crônicos, comprometimento da saúde física e mental, e redução na qualidade de vida. Conclusão: Os resultados desta revisão reforçam a necessidade de medidas para melhorar a qualidade do sono dos trabalhadores de turnos, estratégias de prevenção e suporte psicossocial para reduzir os impactos negativos da insônia.
Cetamina no tratamento do Transtorno Obsessivo-Compulsivo: uma revisão sistemática
Authors: Melo Grécia Silva , Santos Naiara Barbosa , Rodrigues Gabriela Neto , Menezes Mariana Bomfim de , Hajel Victor Abdalla
Published: August 2024

Objetivo: Este artigo de revisão sistemática de literatura tem como objetivo sintetizar as evidências científicas disponíveis sobre o uso e a eficácia da cetamina no tratamento do TOC. Metodologia: Foi conduzida uma revisão sistemática da literatura utilizando bases de dados científicas para identificar estudos clínicos, ensaios controlados e revisões sistemáticas relevantes. Resultados e Discussão: Estudos demonstraram níveis mais elevados de glutamato no líquido cefalorraquidiano de doentes com TOC sem tratamento do que em pacientes saudáveis. Dessa forma, a cetamina destaca-se como um potente antagonista não competitivo do receptor N-metil-D-aspartato. Há evidências de que a cetamina pode ter um efeito mais prolongado numa população com TOC menos refratária ao tratamento, apresentando rápidos efeitos antiobsessivo e anticompulsivo em estudos pré-clínicos e clínicos. Materiais, sujeitos e métodos: Para a elaboração deste artigo de revisão foram consultados artigos científicos e de revisão publicados e referenciados na Scihub/PubMED, SciELO e Google Acadêmico entre 2013 e 2023.
Ceratite Bacteriana: uma revisão da literatura
Authors: Carbbone Gabriela Candida de Albuquerque , Ferreira Beatriz Damianci , Rosa Luís Otávio Sousa , Lins Luisa Acioli
Published: August 2024

A ceratite bacteriana é uma infecção ocular grave que pode levar à perda de visão se não tratada adequadamente. Este artigo apresenta uma revisão sistemática da literatura sobre ceratite bacteriana, com o objetivo de identificar os principais agentes etiológicos, fatores de risco, métodos de diagnóstico, opções de tratamento e prognóstico. Foram selecionados artigos em português publicados em revistas brasileiras, seguindo os critérios de inclusão e exclusão previamente definidos. Os resultados indicam que os principais agentes etiológicos são as bactérias Staphylococcus aureus e Pseudomonas aeruginosa, e os fatores de risco incluem o uso de lentes de contato e traumas oculares. As opções de tratamento variam de acordo com o agente etiológico e a gravidade da infecção, sendo os antibióticos tópicos a primeira linha de tratamento. Conclui-se que a ceratite bacteriana requer diagnóstico e tratamento precoce para evitar complicações graves.
Ectasia Corneana: uma revisão da literatura
Authors: Spanevello Vanessa Rigon , Oliveira Mirella Izabel Rodrigues de , Faria Natália de Matos , Palácios Junior Esteban
Published: August 2024

A ectasia corneana representa um grupo de desordens que levam ao afinamento e protrusão da córnea, resultando em irregularidades que comprometem a visão. Esta revisão sistemática da literatura tem como objetivo explorar as principais causas, diagnósticos, tratamentos e prognósticos associados a essa condição. Foram analisados artigos publicados em bases de dados nacionais e internacionais, enfatizando pesquisas brasileiras. Os resultados indicam avanços significativos no diagnóstico precoce e na intervenção terapêutica, apesar das limitações associadas ao manejo clínico. Conclui-se que uma abordagem multidisciplinar e contínua pesquisa são essenciais para melhorar o prognóstico dos pacientes afetados.
Melanoma de corpo ciliar e coroide: uma revisão de literatura
Authors: Nascimento Joice Raquel Urbano do , Dutra Giulia Valcanaia , Pidde Arthur Gomes , Youssef Junior Marwan Elias
Published: August 2024

O melanoma de corpo ciliar e coroide representa uma neoplasia ocular rara, porém agressiva, com consideráveis implicações prognósticas e terapêuticas. Esta revisão sistemática tem como objetivo analisar a literatura brasileira sobre o tema, abordando aspectos epidemiológicos, diagnósticos, terapêuticos e prognósticos. A metodologia envolveu a busca de artigos em bases de dados científicas, incluindo SciELO e LILACS, com critérios rigorosos de inclusão e exclusão. Os resultados evidenciam a importância do diagnóstico precoce e a diversidade de abordagens terapêuticas disponíveis, destacando a braquiterapia, a fotocoagulação a laser e a enucleação. Conclui-se que o manejo do melanoma de corpo ciliar e coroide deve ser multidisciplinar e individualizado, visando a preservação visual e a qualidade de vida do paciente.
Síndrome de Wyburn-Mason: uma revisão da literatura
Authors: Sousa Isaías Filipe Assunção de , Campos Júnior Crispim Elias , Silva Caio Elias Palasios , Almeida Emilia Gama de , Lins Igor do Nascimento
Published: August 2024

A Síndrome de Wyburn-Mason é uma condição rara caracterizada por malformações arteriovenosas que afetam o sistema nervoso central e os olhos. Este artigo revisa a literatura brasileira sobre essa síndrome, discutindo aspectos clínicos, diagnósticos e terapêuticos. Foram analisados estudos disponíveis em bases de dados nacionais, com o objetivo de compilar informações relevantes e atualizadas. Os resultados destacam a complexidade do diagnóstico e manejo dessa condição, enfatizando a importância de uma abordagem multidisciplinar. Conclui-se que a escassez de dados epidemiológicos e a variabilidade dos achados clínicos representam desafios significativos para a comunidade médica.
Síndrome de Cohen: uma revisão de literatura
Authors: Dutra Matheus Ribeiro Leite , Borges Victoria de Oliveira Carmo , Diniz Raphael Helvecio Carvalho de Oliveira
Published: August 2024

A Síndrome de Cohen é uma desordem genética rara caracterizada por múltiplas anomalias congênitas e deficiências intelectuais. Este artigo apresenta uma revisão sistemática da literatura sobre a Síndrome de Cohen, abordando aspectos clínicos, diagnósticos e terapêuticos. Utilizamos bases de dados como PubMed, SciELO e LILACS para identificar estudos relevantes publicados entre 2000 e 2023. Foram incluídos artigos que descreveram casos clínicos, estudos de coorte e revisões sobre a Síndrome de Cohen. Os resultados evidenciam a complexidade do diagnóstico e a necessidade de abordagens multidisciplinares para o manejo dos pacientes.
Comunicação de más notícias em oftalmologia: uma revisão de literatura
Authors: Vargas Aline Bezerra , Smith Narelly Araújo , Doveinis Rafael Bauer , Mendes Gabriel Pereira
Published: August 2024

A comunicação de más notícias é um desafio constante na prática médica, especialmente em áreas delicadas como a oftalmologia. Este artigo realiza uma revisão sistemática da literatura sobre as estratégias e impactos da comunicação de diagnósticos adversos em oftalmologia. A revisão abrange estudos brasileiros e internacionais, destacando técnicas recomendadas, barreiras enfrentadas por médicos e pacientes, e os efeitos emocionais envolvidos. Os resultados indicam a necessidade de treinamento específico para os oftalmologistas, visando melhorar a relação médico-paciente e minimizar o impacto negativo das más notícias. Conclui-se que a comunicação eficaz é essencial para o manejo adequado das condições oftalmológicas graves.
Atrofia retinocoroideana paravenosa pigmentada: dois relatos de caso e uma revisão de literatura
Authors: Isobata Thaís Naves , Sperandio Ana Luiza Messias , Rabêlo Marina Ferreira , Brito João Victor Vasconcelos de , Takatsu Eduarda
Published: August 2024

A atrofia retinocoroideana paravenosa pigmentada é uma condição ocular rara, caracterizada por alterações degenerativas na retina e na coroide ao longo das veias paravenosas. Este artigo apresenta dois relatos de caso dessa patologia, seguido de uma revisão sistemática da literatura disponível. Através da análise dos casos e da literatura, buscamos entender melhor as manifestações clínicas, o diagnóstico, as possíveis causas e os tratamentos existentes. A revisão inclui artigos publicados até 2023, com ênfase em estudos brasileiros. As conclusões apontam para a necessidade de maior investigação e acompanhamento dos pacientes para um melhor manejo da doença.