bluuebunny/crossref_metadata_2025 huggingface dataset:
Alkali treatment–acid leaching of rare earth elements from phosphogypsum fertilizer: insight for additional resource of valuable components
Authors: Gasser M. S. , Ismail Z. H. , Abu Elgoud E. M. , Hai F. Abdel , Ali I. O. , Aly H. F.
Published: July 2022

Phosphogypsum (PG) is the main by-product of phosphoric acid, which is produced by the sulfuric acid attack of phosphate rocks, wet process. This by-product, which contains around 2.0% phosphoric acid, is used as a low-cost soil fertilizer, PGF. PGF consists mainly of gypsum (CaSO4·2H2O), P2O5, SiO2, and other impurities, including a minor amount of rare earth elements, REEs. In general, phosphate rocks contain from about 0.04 to 1.0% REE, which are precipitated with PG. Now, REEs are considered as strategic elements. Therefore, PG is now regarded as a secondary source of REE. This paper address a process for the separation of REEs and sodium sulphate as a product from PGF. This paper is based on the metathesis of the bulk of PGF with sodium carbonate to obtain calcium carbonate precipitated contain REEs. Furthermore, sodium sulphate was obtained as a product. Calcium carbonate containing REEs was leached out by citric acid as a green acid or nitric acid. At optimum conditions, maximum leaching of REEs from CaCO3 after one cycle of leaching by 3.0 mol/L nitric acid at L/S = 3/1, agitation time of 180.0 min., and at a temperature of 25 °C is 75.1%, 361.10 mg/kg from the total REEs present in PGF. While, the maximum leaching of 87.4%, 420.2 mg/kg of REEs from CaCO3 after one cycle of leaching by 1.0 mol/L citric acid, L/S = 5/1, agitation time of 15.0 min., and 85 °C. The REEs that were obtained in the leaching citrate solutions were purified by solvent extraction using 10% of di-2-ethyl hexyl phosphoric acid, HDEHP, in kerosene. The extracted REEs were stripped by 0.5 mol/L H2SO4. The stripped solutions were further treated with 10.0% oxalic acid to precipitate the REEs. The developed procedure can recover REEs from PGF with an efficiency of 85.2% and a purity of 97.7%.
Characterization and manipulation of the bacterial community in the midgut of Ixodes ricinus
Authors: Guizzo Melina Garcia , Dolezelikova Kristyna , Neupane Saraswoti , Frantova Helena , Hrbatova Alena , Pafco Barbora , Fiorotti Jessica , Kopacek Petr , Zurek Ludek
Published: July 2022

Background

Ticks are obligate hematophagous arthropods transmitting a wide range of pathogens to humans and animals. They also harbor a non-pathogenic microbiota, primarily in the ovaries and the midgut. In the previous study on Ixodes ricinus, we used a culture-independent approach and showed a diverse but quantitatively poor midgut bacterial microbiome. Our analysis also revealed the absence of a core microbiome, suggesting an environmental origin of the tick midgut microbiota.

Methods

A bacterial analysis of the midgut of adult females collected by flagging from two localities in the Czech Republic was performed. Using the culture-independent approach, we tested the hypothesis that the midgut microbiome is of the environmental origin. We also cultured indigenous bacteria from the tick midgut and used these to feed ticks artificially in an attempt to manipulate the midgut microbiome.

Results

The midgut showed a very low prevalence and abundance of culturable bacteria, with only 37% of ticks positive for bacteria. The culture-independent approach revealed the presence of Borrelia sp., Spiroplasma sp., Rickettsia sp., Midichloria sp. and various mainly environmental Gram-positive bacterial taxa. The comparison of ticks from two regions revealed that the habitat influenced the midgut bacterial diversity. In addition, the midgut of ticks capillary fed with the indigenous Micrococcus luteus (Gram-positive) and Pantoea sp. (Gram-negative) could not be colonized due to rapid and effective clearance of both bacterial taxa.

Conclusions

The midgut microbiome of I. ricinus is diverse but low in abundance, with the exception of tick-borne pathogens and symbionts. The environment impacts the diversity of the tick midgut microbiome. Ingested extracellular environmental bacteria are rapidly eliminated and are not able to colonize the gut. We hypothesize that bacterial elimination triggered in the midgut of unfed adult females is critical to maintain low microbial levels during blood-feeding.

Graphical Abstract
Noninvasive early detection of colorectal cancer by hypermethylation of the LINC00473 promoter in plasma cell-free DNA
Authors: Ruiz-Bañobre Juan , Rodriguez-Casanova Aitor , Costa-Fraga Nicolas , Bao-Caamano Aida , Alvarez-Castro Ana , Carreras-Presas Martín , Brozos-Vazquez Elena , Vidal-Insua Yolanda , Vazquez-Rivera Francisca , Candamio-Folgar Sonia , Mosquera-Presedo Manuel , Lago-Lestón Ramón M. , Muinelo-Romay Laura , Vázquez-Bueno José Ángel , Sanz-Pamplona Rebeca , Moreno Víctor , Goel Ajay , Castillo Lourdes , Martin Ana C. , Arroyo Rocio , Esteller Manel , Crujeiras Ana B. , López-López Rafael , Díaz-Lagares Angel
Published: July 2022

Background

Current noninvasive assays have limitations in the early detection of colorectal cancer. We evaluated the clinical utility of promoter methylation of the long noncoding RNA LINC00473 as a noninvasive biomarker to detect colorectal cancer and associated precancerous lesions.

Methods

We evaluated the epigenetic regulation of LINC00473 through promoter hypermethylation in colorectal cancer cell lines using bisulfite genomic sequencing and expression analyses. DNA methylation of LINC00473 was analyzed in primary colorectal tumors using 450K arrays and RNA-seq from The Cancer Genome Atlas (TCGA). Tissue-based findings were validated in several independent cohorts of colorectal cancer and advanced colorectal polyp patients by pyrosequencing. We explored the clinical utility of LINC00473 methylation for the early detection of colorectal cancer in plasma cell-free DNA by quantitative methylation-specific PCR and droplet digital PCR.

Results

LINC00473 showed transcriptionally silencing due to promoter hypermethylation in colorectal cancer cell lines and primary tumors. Methylation of the LINC00473 promoter accurately detected primary colorectal tumors in two independent clinical cohorts, with areas under the receiver operating characteristic curves (AUCs) of 0.94 and 0.89. This biomarker also identified advanced colorectal polyps from two other tissue-based clinical cohorts with high diagnostic accuracy (AUCs of 0.99 and 0.78). Finally, methylation analysis of the LINC00473 promoter in plasma cell-free DNA accurately identified patients with colorectal cancer and advanced colorectal polyps (AUCs of 0.88 and 0.84, respectively), which was confirmed in an independent cohort of patients.

Conclusions

Hypermethylation of the LINC00473 promoter is a new promising biomarker for noninvasive early detection of colorectal cancer and related precancerous lesions.
Robustness of the long-term nonlinear evolution of global sea surface temperature trend
Authors: Xu Zhenhao , Huang Gang , Ji Fei , Liu Bo , Chang Fei , Li Xichen
Published: July 2022

The multi-scale variability of global sea surface temperature (GSST), which is often dominated by secular trends, significantly impacts global and regional climate change. Previous studies were mainly carried out under linear assumptions. Even if the nonlinear evolution patterns have been discussed based on annual-mean data, the conclusions are still insufficient due to several factors. Here, based on the Ensemble Empirical Mode Decomposition (EEMD) method, the robustness of GSST trends tied to the sampling frequency and time interval selection is further explored. The main features derived from the annual-mean data are maintained. However, monthly and seasonal-mean data both mute the cooling in the equatorial central Pacific and the Southern Ocean in the Pacific sector, meanwhile intensify and expand the warming over the North Pacific. The results also highlight that early data cause a minimal effect on secular trends except for the portion near the start point of the interval due to the local temporal nature of EEMD. Overall, the long-term GSST trends extracted by EEMD have good robustness. Our research also clarifies that quadratic fitting cannot reveal all the meaningful evolution patterns, even as a nonlinear solution.
Nanoscale fluorescence imaging of biological ultrastructure via molecular anchoring and physical expansion
Authors: Wang Wei , Chan Yat Ho , Kwon SoYoung , Tandukar Jamuna , Gao Ruixuan
Published: July 2022

Nanoscale imaging of biological samples can provide rich morphological and mechanistic information about biological functions and dysfunctions at the subcellular and molecular level. Expansion microscopy (ExM) is a recently developed nanoscale fluorescence imaging method that takes advantage of physical enlargement of biological samples. In ExM, preserved cells and tissues are embedded in a swellable hydrogel, to which the molecules and fluorescent tags in the samples are anchored. When the hydrogel swells several-fold, the effective resolution of the sample images can be improved accordingly via physical separation of the retained molecules and fluorescent tags. In this review, we focus on the early conception and development of ExM from a biochemical and materials perspective. We first examine the general workflow as well as the numerous variations of ExM developed to retain and visualize a broad range of biomolecules, such as proteins, nucleic acids, and membranous structures. We then describe a number of inherent challenges facing ExM, including those associated with expansion isotropy and labeling density, as well as the ongoing effort to address these limitations. Finally, we discuss the prospect and possibility of pushing the resolution and accuracy of ExM to the single-molecule scale and beyond.
Producing Korean literature (KLit) for export
Authors: Levitt Peggy , Shim Bo-Seon
Published: July 2022

How does art from what have been culturally peripheral countries that were not former colonies of Western powers scale shift or find its way to the global center? What can the Korean case tell us about the circulation of contemporary literature in a “small language?” The scholarly literature offers many answers to these questions: the role of intermediaries, the power dynamics within the world system of translation, the topographies of literary circulation, and a range of other political, cultural, economic, and social factors. We propose that the Korean case sheds new light on these discussions in several important ways loosely subsumed under the umbrella of infrastructures—the platforms, passageways, containers, and gates that organize the writing, reading, publishing, and marketing of the literature. We see three kinds of infrastructures as catalysts of Korean literary success including infrastructures of export and promotion, infrastructures of discovery and consecration, and infrastructures of connection and vernacularization.
The influence of psychological interventions on surgical outcomes: a systematic review
Authors: Lanini Iacopo , Amass Timothy , Calabrisotto Caterina Scirè , Fabbri Sergio , Falsini Silvia , Adembri Chiara , Di Filippo Alessandro , Romagnoli Stefano , Villa Gianluca
Published: July 2022

Background

An amplified and/or prolonged surgical stress response might overcome the organs’ functional reserve, thus leading to postoperative complications. The aim of this systematic literature review is to underline how specific psychological interventions may contribute to improve surgical outcomes through the positive modulation of the surgical stress response in surgical patients.

Methods

We conducted a comprehensive literature search in the Cochrane Register of Controlled Trials, PubMed, EMBASE, Scopus, PsycINFO, and CINAHL databases. Only studies published in English from Jan 2000 to Apr 2022 and reporting pain and/or anxiety among outcome measures were included in the review. The following psychological interventions were considered: (1) relaxation techniques, (2) cognitive-behavioral therapies, (3) mindfulness, (4) narrative medicine, (5) hypnosis, and (6) coping strategies.

Results

Among 3167 records identified in the literature, 5 papers were considered eligible for inclusion in this review because reporting the effects that psychological features have on neurochemical signaling during perioperative metabolic adaptation and those metabolic and clinical effects that the psychological interventions had on the observed population.

Conclusion

Our findings confirm that psychological interventions may contribute to improve surgical outcomes via the positive influence on patients’ metabolic surgical stress response. A multidisciplinary approach integrating physical and non-physical therapies can be considered a good strategy to successfully improve surgical outcomes in the perioperative period.
Teprotumumab Divergently Alters Fibrocyte Gene Expression: Implications for Thyroid-associated Ophthalmopathy
Authors: Fernando Roshini , Smith Terry J
Published: July 2022

Context

Teprotumumab, an IGF-I receptor (IGF-IR) inhibitor, is effective in thyroid-associated ophthalmopathy (TAO). The drug can modulate induction by TSH of IL-6 and IL-8 in CD34+ fibrocytes and their putative derivatives, CD34+ orbital fibroblasts (CD34+ OF). Fibrocytes express multiple thyroid autoantigens and cytokines implicated in TAO, which are downregulated by Slit2. Inflammation and disordered hyaluronan (HA) accumulation occur in TAO. Whether teprotumumab alters these processes directly in fibrocytes/CD34+ OF remains uncertain.

Objective

Determine teprotumumab effects on expression/synthesis of several TAO-relevant molecules in fibrocytes and GD-OF.

Design/Setting/Participants

Patients with TAO and healthy donors were recruited from an academic endocrine and oculoplastic practice.

Main outcome measures

Real-time PCR, specific immunoassays.

Results

Teprotumumab attenuates basal and TSH-inducible autoimmune regulator protein, thyroglobulin, sodium iodide symporter, thyroperoxidase, IL-10, and B-cell activating factor levels in fibrocytes. It downregulates IL-23p19 expression/induction while enhancing IL-12p35, intracellular and secreted IL-1 receptor antagonists, and Slit2. These effects are mirrored by linsitinib. HA production is marginally enhanced by teprotumumab, the consequence of enhanced HAS2 expression.

Conclusion

Teprotumumab affects specific gene expression in fibrocytes and GD-OF in a target-specific, nonmonolithic manner, whereas IGF-IR control of these cells appears complex. The current results suggest that the drug may act on cytokine expression and HA production systemically and locally, within the TAO orbit. These findings extend our insights into the mechanisms through which IGF-IR inhibition might elicit clinical responses in TAO, including a potential role of Slit2 in attenuating inflammation and tissue remodeling.
Physiological Effects of Single and Double Face Mask Use with Moderate and Vigorous Exercise
Authors: LaBotz Michele , Stroshine Karli , Dekker Ellie , Visich Paul
Published: July 2022

Introduction/Purpose

Exercise is associated with increased exhalation of infectious particles in respiratory disease, and face mask use has become routine during the coronavirus disease 2019 (COVID-19) pandemic to mitigate particle spread. As of February 2022, the U.S. Centers for Disease Control and Prevention (CDC) continues to recommend the use of double masking (i.e., cloth masks worn over a surgical mask) to minimize particle leakage seen with single-mask use. Studies to date have examined the effects of single masks on exercise safety and performance, but the potential added burden during exercise of an additional mask layer has not been evaluated. The purpose of our study was to compare the effects of single and double face mask use during moderate to vigorous exercise.

Methods

Fifteen healthy, physically active young adults (mean age = 21.1 ± 0.8 yr; 8 males and 7 females; V˙O2peak = 46.3 ± 11.5 mL·kg−1⋅min−1) completed the study. This included an initial assessment of V˙O2peak, with subjects returning for three exercise test sessions performed while wearing either a surgical face mask, a cloth face mask, or double masks (i.e., a cloth mask worn over a surgical mask) in a random order. Test sessions consisted of a progressive cycling protocol with 10-min stages at 40%, 60%, and 75% oxygen consumption reserve (VO2R). Assessments were performed after 5 and 10 min at each exercise intensity and included heart rate, respiratory rate, oxygen saturation, and ratings of perceived exertion and dyspnea.

Results

At exercise intensities from 40% to 75% VO2R, there were no significant differences between cloth masks, surgical masks, and double masking in the measured subjective and physiologic parameters.

Conclusions

When compared with surgical and cloth face masks in common use, for the outcomes measured in this study, double masking in accordance with CDC recommendations does not result in significant impairments during moderate to vigorous exercise up to 75% VO2R in healthy young adults.
Osteoporosis screening support system from panoramic radiographs using deep learning by convolutional neural network
Authors: Nakamoto Takashi , Taguchi Akira , Kakimoto Naoya
Published: July 2022

Objectives:

This study was performed to develop computer-aided screening systems that could predict osteoporosis. The systems were constructed using panoramic radiographs of women aged ≥ 50 years through three types of deep convolutional neural networks (CNNs): Alexnet, VGG-16, and GoogLeNet; the performances of the constructed systems were evaluated.

Methods:

One oral radiologist classified 1500 panoramic radiographs into three types. In C1, the endosteal margin of the cortex was smooth and sharp, whereas porosities were observed in C2 and C3. The risks of osteoporosis were higher in C2 and C3 than in C1; C3 had the highest risk. This information was included with the images as training data; three CNNs were transfer trained. Using each trained CNN, the diagnostic accuracy was assessed using panoramic radiographs and bone mineral density inspection findings in the lumbar spine and femoral neck of 100 additional patients.

Results:

All CNNs exhibited relatively good agreement with the oral radiologist’s judgement (86.0%–90.7%). The predictive results of the three systems for osteoporosis of the lumbar spine showed sensitivities of 78.3%–82.6%, specificities of 71.4%–79.2%, and accuracies of 74.0%–79.0%. The predictive results for osteoporosis of the femoral neck showed sensitivities of 80.0%–86.7%, specificities of 67.1%–74.1%, and accuracies of 70.0%–75.0%.

Conclusions:

The constructed systems were generally more accurate than the previously developed conventional system. The new systems may facilitate osteoporosis prediction and prevent subsequent fractures by encouraging patients with suspected osteoporosis to undergo further inspections (e.g., dual-energy X-ray absorptiometry) and treatment.
OS SENTIDOS DE AMÉLIA NA CANÇÃO DESCONSTRUINDO AMÉLIA
Authors: Dornas Nayara Fernanda
Published: July 2022

Resumo: A proposta do presente artigo é analisar o sentido de Amélia ao longo da música da Locutora Pitty. Para isso, vamos adotar os procedimentos da Semântica do Acontecimento (2005) desenvolvida por Eduardo Guimarães, especificamente, seus procedimentos de análise de texto (2017), analisando as reescriturações do nome Amélia, a designação do nome Amélia e a constituição da cena enunciativa. Observamos que ao longo do acontecimento da canção, o sentido de Amélia é ressignificado e atualizado. Portanto a música constitui-se de uma fonte inesgotável de sentidos, que surgem e circulam na sociedade, afetando-a, influenciando-a. Assim, como veremos ao longo das análises, ao se tornar sucesso, a música de Mário e Ataulfo projetou o sentido de Amélia que é ressignficado por meio do sucesso de Pitty, projetando um sentido diferente do cristalizado. Dessa forma, a Locutora Pitty atualiza a sentido de Amélia, agenciada pela historicidade do acontecimento e pelo presente do acontecimento associado ao memorável.
Resenha: Sentidos de milícia e uma comunicação dialógica
Authors: De Oliveira Pasini Mônica
Published: July 2022

Esta resenha ao apresentar o livro “Sentidos de Milícia: entre a lei e o crime” de Greciely Cristina da Costa, pesquisadora do Laboratório de Estudos Urbanos - Labeurb - da Universidade Estadual de Campinas - Unicamp, busca identificar uma articulação entre a Análise de Discurso e a Comunicação Dialógica.
Observações para o fazer e pensar científico-comunicacional sobre mídias, identidades culturais e cidadania
Authors: Krambeck Rafael Soares
Published: July 2022

Neste texto, proponho recuperar e problematizar abordagens teóricas, para pensar as relações estabelecidas entre identidades culturais e cidadania no contexto contemporâneo de intensos processos sociais de midiatização, buscando refletir as ações comunicativas dos sujeitos enquanto práticas que renovam os processos contemporâneos de constituição da cidadania, no âmbito comunicacional. No percurso dessa reflexão, inicialmente, articulo concepções de Braga (2012), Fausto Neto (2008) e Gomes (2019) sobre as implicações da midiatização e da digitalização trazidas pela “sociedade de midiatização” para os processos sociais contemporâneos. Logo, busco em autores como Maldonado (2011), Cortina (2005) e Martin-Barbero (2014), as contribuições necessárias para transcender a concepção moderna e liberal de cidadania, incorporando dimensões compreensivas e constitutivas de maneira a trabalhar problemáticas como hibridações, diásporas, miscigenações nos processos comunicacionais. Finalmente, examino potencialidades e complexidades trazidas à luz por perspectivas que incorporam a cultura sob vista das complexidades sociais e da heterogeneidade da produção simbólica que as culturas apresentam como retornos às novas demandas e táticas de embate.
Comunicação pública e políticas sociais: uma conexão de princípios
Authors: Figueiredo Kenia Augusta
Published: July 2022

Este artigo tem por objetivo refletir acerca da conexão entre os princípios da Comunicação Pública e as políticas sociais. Neste tempo de mundialização do capital, apoiado nas Tecnologias de Informação e Comunicação – TICs, sob hegemonia neoliberal é preciso encontrar possibilidades que contribuam para potencializar a organização política de segmentos da classe trabalhadora, pois a democracia e o acesso à direitos vêm sendo corroídos aceleradamente. As políticas sociais, um campo onde se travam as disputas de classe são um espaço fértil à formação econômica, política e social. Há, portanto, uma conexão entre os princípios da Comunicação Pública e as Políticas Sociais uma vez alinhavados na práxis do cotidiano, por meio da comunicação dialógica podem contribuir para a emancipação política e o fortalecimento da democracia com consciência de classe.
PEDAGOGIA ANTIRRACISTA E PROCESSOS IDENTITÁRIOS: TEORIA E PRÁTICA NA EDUCAÇÃO INFANTIL
Authors: Amorim Juliana Pires Pessôa
Published: July 2022

Este artigo tem como tema Pedagogia Antirracista e Educação Infantil, e configura os primeiros registros de pesquisa iniciada para fins de trabalho de conclusão do curso Ações Afirmativas e Políticas Públicas (ProDEd - TS/UERJ). Enquanto mãe de criança pequena, servidora em escola pública e futura pedagoga, deparei-me diversas vezes com padrões racistas como obstáculo ao cumprimento dos princípios previstos na Constituição (BRASIL, 1988) e na LDB (BRASIL, 1996). Assim, a fim de analisar as consequências de práticas pedagógicas antirracistas nos processos identitários na Educação Infantil, a metodologia utilizada foi revisão bibliográfica alinhada a estudo de caso. Na primeira seção, a proposta é conceituar educação antirracista; na segunda, apresentar nuances dos processos identitários infantis; e na terceira, relacionar teoria e prática mediante estudo de caso. Finalmente, a associação entre estudos relacionando questões raciais e Educação Infantil à prática docente de uma professora integrante de NEABI encaminhou as considerações finais em direção a constatações, alternativas e indagações para a continuidade da pesquisa futuramente.
RESISTÊNCIAS, AVANÇOS E TENSÕES DO PROJETO SOCIETÁRIO CUBANO NO PENSAMENTO DE FLORESTAN FERNANDES
Authors: Leite Maria do Carmo Luiz Caldas
Published: July 2022

O legado de Florestan Fernandes traz à tona algumas das interpretações mais relevantes sobre as condições e possibilidades de transformação do projeto societário em Cuba. O pensamento dialético do autor pode ser captado de modo original, desde os desafios abertos pelo passado da sociedade colonial cubana até os primórdios do poder popular. Partindo da afirmação que sua obra integra os estudos mais amplos sobre a Revolução vitoriosa em 1959, por sua vigência, merece ser revisitada. O percurso do presente artigo busca realizar um diálogo entre o sociólogo brasileiro e diversos pesquisadores militantes por um pensamento distanciado do colonialismo cultural, além de expressar reflexões oriundas do trabalho de campo realizado em Cuba pela autora do texto, ao longo das quatro últimas décadas. O relacionamento com professores, alunos e dirigentes das organizações de massa possibilitaram a formulação de uma postura mais profunda acerca da maior das Antilhas. As principais evidências deste exercício apontam que a história da Ilha produziu uma cultura de resistências e uma pedagogia de lutas de características autóctones com claros reflexos nos movimentos revolucionários de nosso continente.
O TRABALHO DO PEDAGOGO ESCOLAR STRICTO SENSU: UMA PROPOSTA PARA A ORGANIZAÇÃO DA PRÁTICA PEDAGÓGICA
Authors: Teixeira da Silva Livaldo
Published: July 2022

ResumoEsse estudo sobre a organização do trabalho do Pedagogo Escolar tem como objetivo geral, apresentar o labor profissional numa visão que considere a história da formação e atuação e, especificamente, construir uma proposta com princípios coerentes às demandas das instituições de Educação, Ciência e Tecnologia. Trata-se da sistematização da experiência com projetos extensionistas, considerando conceitos e reflexões sobre a problemática, fundamentados em uma concepção da educação que ressalta o valor do trabalho pedagógico escolar, e assim, dão suporte à docência e a gestão das instituições educativas. Propomos aqui a integração desse profissional em uma proposta respaldada por fazeres que não dissociam a teoria da prática pedagógica na formação e atuação Stricto sensu. Para tanto, propomos a articulação da prática desse profissional em sete eixos laborais, de maneira a propiciar um contorno capaz de responder as demandas apresentadas de maneira efetiva, e que o pedagogo, tenha maior domínio da especificidade e da natureza da prática na educação escolar.Palavras-chave:Pedagogo Escolar; Organização do Trabalho Pedagógico; Instituições de Educação Ciência e Tecnologia; Eixos Laborais.
A LITERATURA DO RAPPER EMICIDA COMO REFERÊNCIA PARA UMA EDUCAÇÃO ANTIRRACISTA
Authors: Galieta Tatiana
Published: July 2022

Alinhada a estudos anteriores que utilizam a cultura Hip-Hop na educação formal, considero a literatura do rapper Emicida como referência para uma educação antirracista que discuta as diversas dimensões (histórica, social, científica e religiosa) do racismo brasileiro. Faço um levantamento de sua obra completa, seguida pela identificação dos temas recorrentes nela para o estabelecimento de categorias temáticas. Somente foram considerados os três álbuns de estúdio com o total de 39 faixas. De 13 temas inicialmente identificados compilei sete categorias: materialidade da vida; relações interpessoais; ancestralidade e espiritualidade; racismo e resistência negra; corporalidade; referências (eventos e personagens); e natureza. Após a classificação nas categorias, nove músicas foram selecionadas.  Em diálogo com intelectuais negros/as, foram explorados elementos que subsidiam uma educação antirracista.
OS MÉTODOS DE PAULO FREIRE E NISE DA SILVEIRA: CONTRIBUIÇÕES AO PROJETO ÉTICO-POLÍTICO DO SERVIÇO SOCIAL
Authors: Scheffer Graziela Machado , Santos Andressa Moura , Silva Domênica Borges
Published: July 2022

O artigo é fruto de estudo exploratório pautado em obras, entrevistas e documentários acerca de Nise da Silveira e Paulo Freire, bem como, literatura pertinente a temática do Serviço Social na interface com a educação popular e arte. O objetivo geral é apresentar o pensamento teórico-prático dos autores com ênfase nos métodos na interlocução com o projeto ético-político profissional, buscando dar visibilidade às contribuições na atualidade
EDUCACIÓN POPULAR: INTERVENCIÓN ARTÍSTICA CON POEMAS DE BENEDETTI EN OLLAS POPULARES.
Authors: Nibia Silveira Rondán Nahir
Published: July 2022

Este artículo presenta un relato de experiencia de Educación Popular en Ollas Populares de las barriadas más humildes de Montevideo; a través de intervenciones artísticas con poemas de Mario Benedetti, cuyo objetivo fue realizar intervenciones artísticas con poemas de Benedetti, a partir de la metodología que nos brinda la Educación Popular. Encontramos una puerta hacia el ejercicio de una identidad ciudadana abierta a la resistencia. Unimos a ambos en sus centenarios. Estas intervenciones tuvieron un carácter de autonomía y dignidad referido a lo pedagógico. La “pedagogía del diálogo” fue puesta en práctica como una herramienta de afirmación y potenciación de construcción de subjetividades y sentidos en resistencia, un paso previo y condición necesaria para su emancipación. Sin embargo, vale preguntarse una y otra vez: ¿resistencia o sobrevivencia? ¿Cuándo es que esta sobrevivencia traspasa el límite y se convierte en resistencia? ¿Cuántas y cuáles de estas subjetividades de oprimidos sobrevivientes en medio del hambre,  resisten y llegan a emanciparse? A través del arte y de la implementación del diálogo pedagógico pudimos observar que Benedetti y sus poemas mantienen vigencia, construyen y forman parte de: saberes populares, cultura popular, así como de saberes y culturas de resistencia.
A light-emitting diode and microneedling case study for a facial injury
Authors: Soos Emma
Published: July 2022

Emma Soos presents a case study on a recent facial trauma caused by machinery and the results of a program of intense light-emitting diode (LED) 3 wavelength therapy using the Silvery Blue LED system, followed by a course of medical/cosmetic needling with appropriate serums to promote healing
Premises standards
Authors: Mason-Poyner Lisa , Taber Sally
Published: July 2022

Lisa Mason-Poyner and Sally Taber explain the Joint Council for Cosmetic Practitioners’ (JCCP) review of premises standards in relation to how they might inform the new proposed the national licensing scheme, which will be introduced as part of the new Health and Care Act (2022) that has recently received royal assent
The importance of building (and maintaining) trust
Authors: Adams Alan S
Published: July 2022

Alan S Adams explains why building trust among patients (both current and prospective) is important and shares a number of core strategies that can be employed to not only develop that initial trust, but maintain it in the long term to ensure continued and sustainable success for you and those who put their faith in you
Movers and takers: do not let secrets walk out the door
Authors: Waterhouse Grace , Pope Aron
Published: July 2022

Business information is valuable and can easily be abused by a departing employee
Gain-Enhanced Wideband Circularly Polarized Antenna with a Non-Uniform Metamaterial Reflector
Authors: Qiu Bosong , Xia Yinfeng , Li Yingsong
Published: July 2022

In this paper, a gain-enhanced wideband circularly polarized (CP) antenna with a non-uniform metamaterial (NUM) reflector is presented, which is composed of a modified wide S-shaped slot antenna and a NUM reflector. To achieve a wideband CP operation, a modified S-shaped slot is fed by an L-shaped microstrip feedline that ends with a triangular patch to improve axial ratio (AR) bandwidth and impedance bandwidth. A NUM reflector composed of rectangular metal units with different sizes is employed and its units are unevenly distributed. The proposed CP antenna is designed, fabricated, and measured. The measured results show that the impedance bandwidth covers 3.0-6.0 GHz (66.7%) and a 3-dB AR bandwidth covers 3.1-5.6 GHz (57.4%). A peak gain of 6.0 dBi is obtained at 3.8 GHz by using the reflector. The advantages of the proposed antenna are the simple structure, high gain, and broad CP bandwidth.
Giant terahertz pulling force within an evanescent field induced by asymmetric wave coupling into radiative and bound modes
Authors: Ferrari Hernán , Zapata-Rodríguez Carlos J. , Cuevas Mauro
Published: July 2022

Manipulation of nano-scale objects by engineering the electromagnetic waves in the environment medium is pivotal for several particle handling techniques using optical resonators, waveguiding, and plasmonic devices. In this Letter, we theoretically demonstrate the possibility of engineering a compact and tunable plasmon-based terahertz (THz) tweezer using a graphene monolayer that is deposited on a high-index dielectric substrate. When a nanoparticle located in a vacuum in the vicinity of the graphene monolayer is illuminated under total internal reflection, as light is launched from the substrate, such a device is shown to be capable of inducing an enhanced rotating dipole in the nanoparticle thus enabling asymmetric, directional near-field coupling into the graphene plasmon mode and the radiative modes in the substrate. As a result of the total momentum conservation, the net force exerted on the particle points in a direction opposite to the pushing scattering force of the exciting evanescent field. Our results can contribute to novel realizations of photonic devices based on polarization-dependent interactions between nanoparticles and electromagnetic mode fields.
Optical differentiation based on weak measurements
Authors: Wang An , Zhu Junfan , Luo Lan , Liu Xiong , Ye Ling , Zhang Zhiyou , Du Jinglei
Published: July 2022

Optical differentiation shows much potential to be applied in computation due to its strong parallelizability. Currently, each optical differential method can only obtain partial differential information. Here, we propose a general approach to obtain complete differentiation. Compared to previous methods, we can separately obtain the differentiation of amplitude and phase, reserve the negative value of the differentiation, and acquire the differentiation in arbitrary directions of the two-dimensional field. We measure the differentiation of the Gaussian beam to demonstrate this method. A practical experiment of identifying the move direction of the motion-blurred image is also presented to verify the practicability of our method. Our method can further be applied to intelligence algorithms, image identification, and optical analog computing.
Dual resonance akinetic dispersive cavity swept source at 900 kHz using a cFBG and an intensity modulator
Authors: Riha Rene , Bradu Adrian , Podoleanu Adrian
Published: July 2022

In this paper, a fast dual resonance akinetic optical swept source operating at 1550 nm is demonstrated. Instead of modulating the optical amplifier gain reported in our previous studies, here we employ a fiber intensity modulator as a mode-locking element. A chirped fiber Bragg grating is used to provide sufficient dispersion in the laser cavity. A tuning range of 25 nm is obtained for a sweep frequency of ≈900 kHz with a 6-dB drop-off in sensitivity at 2.6-mm optical path difference.
Spatial resolution of omni-resonant imaging
Authors: Shiri Abbas , Abouraddy Ayman F.
Published: July 2022

Omni-resonance refers to the broadening of the spectral transmission through a planar cavity, not by changing the cavity structure, but by preconditioning the incident optical field. As such, broadband imaging can be performed through such a cavity with all the wavelengths simultaneously resonating. We examine here the spatial resolution of omni-resonant imaging and find that the spectral linewidth of the cavity resonance determines the spatial resolution. Surprisingly, the spatial resolution improves at longer wavelengths because of the negative angular dispersion intrinsic to Fabry–Pérot resonances, in contrast to conventional diffraction-limited optical imaging systems where the spatial resolution improves at shorter wavelengths. These results are important for applications ranging from transparent solar windows to nonlinear resonant image processing.
Digital Staging of Hepatic Hemangiomas Reveals Spatial Heterogeneity in Endothelial Cell Composition and Vascular Senescence
Authors: Thomann Stefan , Tóth Marcell , Sprengel Simon David , Liermann Jakob , Schirmacher Peter
Published: July 2022

Hepatic hemangioma (HH) is the most common benign primary liver tumor; however, despite its high prevalence, a stage-specific classification of this tumor is currently missing. For a spatial stage-specific classification, a tissue microarray (TMA) consisting of 98 HHs and 80 hemangioma margins and 78 distant liver tissues was digitally analyzed for the expression of 16 functional and vascular niche-specific markers. For cross-correlation of histopathology and functional characteristics, computed tomography/MRI imaging data of 28 patients were analyzed. Functional and morphological analyses revealed a high level of intra- and interpatient heterogeneity, and morphological heterogeneity was observed with regard to cellularity, vascular diameter, and endothelial cell subtype composition. While regressed hemangiomas were characterized by low blood vessel density, low beta-catenin levels, and a microvascular phenotype, non-regressed HHs showed a pronounced cellular and architectural heterogeneity. Functionally, cellular senescence–associated p16 expression identified an HH subgroup with high vascular density and increased lymphatic endothelial cell content. Histological HH regions may be grouped into spatially defined morphological compartments that may reflect the current region-specific disease stage. The stage-specific classification of HHs with signs of regression and vascular senescence may allow a better disease course–based and cell state–based subtyping of these benign vascular lesions.
Healthcare resource utilization and costs associated with renal, bone and cardiovascular comorbidities among persons living with HIV compared to the general population in Quebec, Canada
Authors: Baribeau Véronique , Kim Connie J. , Lorgeoux René-Pierre , Brisebois Josée , Tossonian Harout , Lachaine Jean
Published: July 2022

There is limited understanding on healthcare utilization and costs of age-related comorbidities such as cardiovascular, bone and renal disease/disorder in people living with human immunodeficiency virus, so we compared comorbidity prevalence and associated healthcare utilization and costs. Through the Quebec health insurance database, people living with human immunodeficiency virus on antiretroviral therapy for ≥6 months from January 2006 to June 2012 were categorized by their comorbidity status using International Classification of Diseases (ICD)-9 codes, and controls without human immunodeficiency virus diagnosis or antiretroviral therapy use were age and gender matched. We compared healthcare utilization and costs. A total of 3,905 people living with human immunodeficiency virus and 11,715 control individuals were included. The mean age of people living with human immunodeficiency virus was 45.3 years and 77.3% were men. Prevalence of comorbidities was higher and occurred earlier in people living with human immunodeficiency virus and increased with older age regardless of human immunodeficiency virus status. Interestingly, bone comorbidity was high (37%) and 5-fold greater in people living with human immunodeficiency virus <20 years than the controls. Polypharmacy and comorbidity scores were greater in people living with human immunodeficiency virus than controls (p<0.01), as were cardiovascular, bone and renal comorbidities (40.3%, 26.0% and 5.5%, respectively; p<0.01). People living with human immunodeficiency virus had higher healthcare utilization and costs than controls largely due to longer hospital stays and prescriptions. Mean total healthcare cost/person/year for people living with human immunodeficiency virus was CAD$6,248 and was highest for those with renal disease (CAD$19,617). Comorbidities in people living with human immunodeficiency virus are more prevalent, occur earlier and incur a higher burden on the healthcare system; earlier screening and improved preventative and management strategies may reduce the burden to people living with human immunodeficiency virus and to the healthcare system.
The unified protocol as an internet-based intervention for emotional disorders: Randomized controlled trial
Authors: Schaeuffele Carmen , Homeyer Sophie , Perea Luis , Scharf Lisa , Schulz Ava , Knaevelsrud Christine , Renneberg Babette , Boettcher Johanna
Published: July 2022

The Unified Protocol (UP) as a transdiagnostic intervention has primarily been applied in the treatment of anxiety disorders and in face-to-face-settings. The current study investigated the efficacy of a 10-week Internet-based adaptation of the UP for anxiety, depressive, and somatic symptom disorders. The trial was registered under DRKS00014820 at the German Clinical Trial Registry, DRKS. Participants (n = 129) were randomized to treatment or waitlist control. Significant treatment effects were found for symptom distress, satisfaction with life, positive/negative affect and markers of anxiety, depression, and somatic symptom burden (within-group Hedges’ g = 0.32–1.38 and between-group g = 0.20–1.11). Treatment gains were maintained at 1- and 6-month-follow-up. Subgroup analyses showed comparable effects in participants with anxiety and depressive disorders. 26.6% dropped out of treatment and 35.38% did not provide post-treatment assessments. The results strengthen the application of the UP as an Internet-based treatment for alleviating symptom distress across emotional disorders. More research on the applicability for single disorders is needed and avenues to improve adherence and attrition rates should be explored.
Evaluating tubulointerstitial compartments in renal biopsy specimens using a deep learning-based approach for classifying normal and abnormal tubules
Authors: Hara Satoshi , Haneda Emi , Kawakami Masaki , Morita Kento , Nishioka Ryo , Zoshima Takeshi , Kometani Mitsuhiro , Yoneda Takashi , Kawano Mitsuhiro , Karashima Shigehiro , Nambo Hidetaka
Published: July 2022

Renal pathology is essential for diagnosing and assessing the severity and prognosis of kidney diseases. Deep learning-based approaches have developed rapidly and have been applied in renal pathology. However, methods for the automated classification of normal and abnormal renal tubules remain scarce. Using a deep learning-based method, we aimed to classify normal and abnormal renal tubules, thereby assisting renal pathologists in the evaluation of renal biopsy specimens. Consequently, we developed a U-Net-based segmentation model using randomly selected regions obtained from 21 renal biopsy specimens. Further, we verified its performance in multiclass segmentation by calculating the Dice coefficients (DCs). We used 15 cases of tubulointerstitial nephritis to assess its applicability in aiding routine diagnoses conducted by renal pathologists and calculated the agreement ratio between diagnoses conducted by two renal pathologists and the time taken for evaluation. We also determined whether such diagnoses were improved when the output of segmentation was considered. The glomeruli and interstitium had the highest DCs, whereas the normal and abnormal renal tubules had intermediate DCs. Following the detailed evaluation of the tubulointerstitial compartments, the proximal, distal, atrophied, and degenerated tubules had intermediate DCs, whereas the arteries and inflamed tubules had low DCs. The annotation and output areas involving normal and abnormal tubules were strongly correlated in each class. The pathological concordance for the glomerular count, t, ct, and ci scores of the Banff classification of renal allograft pathology remained high with or without the segmented images. However, in terms of time consumption, the quantitative assessment of tubulitis, tubular atrophy, degenerated tubules, and the interstitium was improved significantly when renal pathologists considered the segmentation output. Deep learning algorithms can assist renal pathologists in the classification of normal and abnormal tubules in renal biopsy specimens, thereby facilitating the enhancement of renal pathology and ensuring appropriate clinical decisions.
Can Queer Representations in Comedy Be Progressive in the Twenty-First Century?
Authors: Roach Lennox Carlos Encarnacao
Published: July 2022

Oliva film garnered attention through the subversive conversation it placed on-screen effortlessly through the art of comedy. However, scholars Kathleen Battles and Wendy Hilton-Morrow write, “homosexuality can only be represented through heterosexist categories and language, while at the same time it is marked as a deviation from the norm,” this rocky navigation of queerness in heteronormative territories produces the heavy question of if comedy is progressive enough to contribute to the movement of the discourse on queerness. This article answers that question by performing a deep focus on the cinematography, character actions, behaviors, relationships as well as examining their environments that offer the pleasures of comedic and educational glimpses of queer theory on-screen.
Introduction to the Special Issue on ‘Textures of Diaspora and (Post-)Digitality: A Cultural Studies Approach’
Authors: Adenekan Shola , Borst Julia , Maeding Linda
Published: July 2022

This editorial of the Special Issue ‘Textures of Diaspora and (Post-)Digitality: A Cultural Studies Approach’ explores the digital agency of diasporic communities by showing how cultural and literary studies genuinely contribute to scholarly debates and our understanding of digital diasporas. It explores the implications of the digital in a (post-)digital age, one in which the notion of diaspora is used to refer to actual ethnic, religious communities and to collectives that do not necessarily share any common origin or history but articulate their communality through a ‘diaspora rhetoric’. It uses an approach that concentrates on the medial, cultural and aesthetic dimensions of diasporic (self-)representations, positionings and practices in cyberspace. It brings into focus the ‘textures’ of these communities and points to the need to decode diasporic imageries and the many meanings of those portrayals. It studies the textual and visual language with which diasporic communities are imagined in the digital space.
‘Extended diaspora’: On communitization phenomena in the digital age
Authors: Brühne Julia , Kuhlmann Hauke
Published: July 2022

In our article, we will address the question of the extent to which the phenomenon of the digital diaspora can also be transferred to internet communities. Drawing on Foucault’s concepts of heterotopia and heterochronia, we will not only refer to actual diaspora communities, but especially to those communities that make use of diaspora rhetoric and therefore also have a community-building effect. We deal with attempts to create communities that are, on the one hand, located beyond the ‘classical’ definition of diaspora, but, on the other hand, are designed against the background of the connotations of diaspora (extended diaspora). We will examine such an appropriation of the concept using several examples from the fields of video games and digital video. These pop cultural artefacts make use of the term ‘diaspora’ to create a feeling of community in the realm of the digital but without really cashing in on its original meaning.