bluuebunny/crossref_metadata_2025 huggingface dataset:
Доля «негативної свободи» в політичній філософії Т. Гоббса та Ж.-Ж. Руссо
Authors: Usov Dmytro
Published: May 2023

Послідовно реконструюючи філософію свободи Т. Гоббса та Ж.-Ж. Руссо, автор спирається, по-перше, на думку Ю. Габермаса, який обґрунтовано вважає, що без Гоббса та Руссо цілісний образ європейського філософського дискурсу розважливої свободи не буде довершеним. По-друге, – на ту важливу обставину, що започатковані в політичній філософії Гоббса та Руссо образи свободи та справедливості віднайшли своє продовження в творчості таких відомих філософів як Ю. Габермас, Дж Грей, А. Гонет, О. Гьофе, Ч. Тейлор. По-третє, розкриваючи сутність тлумачення Гоббсом «негативної свободи», автор прагне уникнути її спрощеного, «карикатурного» (якщо скористатися висловом Ч. Тейлора) бачення та наголосити на актуальності цього концепту та властивого йому «суворого портрету людської природи» для нашого трагічного сьогодення. Доведено значущість ідей Гоббса про людину та її свободу для філософії Руссо, а також розвинуто тезу про те, що саме Гоббс прагнув всебічно осмислити вкорінені в залежності свободи від безпеки взаємини держави та громадянина, суверена та підданого та доповнити своє бачення «негативної свободи» розумінням її і як свободи совісті, як «права людини і громадянина» на їх визнання державою. До того ж саме в роздумах Гоббса зароджується ідея (розвинена далі в працях Руссо) про взаємозв’язок тлумачення свободи та природи людини. Розкрито також сутність важливого для Руссо поняття згоди, завдяки якій ми добровільно стаємо частиною спільноти: «завершений і самотній» індивід, відмовившись від своєї суверенності на користь якого цілого перетворюється на його частину, залишаючись вільним. У статті зроблено висновок про те, що започаткована Гоббсом та Руссо дискусія про долю «негативної свободи» так і не віднайшла свого остаточного вирішення, незважаючи на спроби таких класиків сучасної філософії як Ч. Тейлор. Його прагнення продемонструвати помилки, «негаразди» зтеоретизованої Т. Гоббсом «негативної свободи», не перетворили його на прихильника свободи «позитивної» через приховану в ній небезпеку тоталітарного насильства. А роздуми Тейлора про градацію перешкод на шляху до свободи не набувають глибини ідей Гоббса, зумовленої трагічними соціальними контекстами його життя.
Платонізм та арістотелізм як джерело відмінностей внутрішньої форми християнських традицій Західної Європи та Візантії доби Середньовіччя (стаття третя – закінчення)
Authors: Bilodid Volodymyr
Published: May 2023

В цій історіософській за «жанром» статті досліджуються особливості ставлення до платонізму й арістотелізму в «власне візантійській філософії» (В. Лур'є) святоотчого традиціоналізму. Автор виходить з того, що в цій духовно-ідейній течії філософська полярність платонізму й арістотелізму постає як у звичній, так і в незвично-перетвореній формі полярності містичного («платонічного») і раціонально-дискурсивного («арістотеліан-ського») способів пізнання. Показано, що в центрі візантійської культури була Церква, вченням якої було богослів'я, його “служницею” – філософія, а їх найголовнішою проблемою – богопізнання, яка, по-різному досліджувалася і вирішувалася в католицизмі і православ'ї. Західне християнство усвідомлювало себе в схоластиці, а східне – в ісіхазмі; там – в слові (в грандіозних “сумах”), тут – в ісіхії, в мовчанні; там – за допомогою раціональних міркувань, тут – спираючись на “третій вид пізнання” – містичний. Вдаючись до історико-богословсько-філософських екскурсів, автор обгрунтовує бачення ісіхазму як власне східно-християнського способу богопізнання і містичного ядра, “серця” православ'я. Обстоюється теза, за якою наявність містиків у католицизмі – це одне, а містичне східно-християнське богослів'я, містична Православна Церква – істотно інше. Доводиться, що на тодішнє головне філософсько-богословське питання – чи може християнин не лише вірити в свого Бога, а й знати його – ісіхасти, а за ними і Візантійська Церква, давали ствердну відповідь. Обгрунтовується думка про те, що за боротьбою (часом доречною, часом недоречною) візантійської влади з платонізмом ховається врешті-решт щось прямо протилежне, але непомічене тоді – зустріч платонічно-неоплатонічної традиції з ісіхазмом, отже, і з православ'ям, оскільки богослов-філософ у ісіхазмі, з одного боку, філософ-богослов у платонічно-неоплатонічній філософії – з другого, перетнулися, перетворившись на одне й те ж – на містиків, яких об'єднувала спільна мета (єднання з божественним) і спосіб її реалізації (містичний), що увиразнює внутрішню спорідненість “візантінізму” саме з платонізмом, і аж ніяк не з альтернативним містиці арістотелізмом.
Development of palm-sized gas treatment device utilizing streamer discharges generated by compact resonant high-voltage pulse generator
Authors: Takahashi Katsuyuki , Suzuki Yuto , Saito Ryo , Kikuchi Takuto , Yamaguchi Riku , Takaki Koichi
Published: May 2023

A compact and lightweight gas treatment system integrated with a high-voltage pulse generator driven by SiC-MOSFET and wires-to-wires electrode. The maximum amplitude and pulse width of the output voltage of the pulse generator without load are 10 kV and 31 ns, respectively, and the maximum energy transfer efficiency reaches 88% with a load resistance of 0.44 kΩ. This pulse generator was applied to multilayered wires-to-wires electrodes, and the streamer discharges propagated between the electrodes were observed. Streamers initially propagate horizontally according to the Laplacian electric field near the high-voltage electrode. When they approach the ground electrodes, they curve and propagate toward the ground electrode due to the high electric field between the streamer head and the ground electrode. The velocity of the streamer propagation is with a velocity of 0.4 to 0.71 × 106 m s−1. Ozone production and ethylene removal characteristics are investigated in a sealed vessel. The result shows a high ethylene removal efficiency and high safety by suppressing the ozone concentration in the exhaust gas with a catalyst.
Structural parameter analysis on 6.5 kV integrated time and space carrier controllable dual-gate HiGT (i-TASC)
Authors: Suzuki Hiroshi , Miyoshi Tomoyuki , Moritsuka Tsubasa , Furukawa Tomoyasu
Published: May 2023

A dual-gate insulated gate bipolar transistor (IGBT), which achieves low loss through dynamic gate control, is a remarkable technology. However, the influence of device structures on switching loss has not been analyzed in detail. In this paper, we clarify the optimal structure in terms of turn-off loss (E
off) reduction for a proposed dual-gate high conductivity IGBT (dual gate HiGT, or i-TASC) that can dynamically control the stored carriers with one-chip fabrication. A boundary region (TS) is introduced in the i-TASC and the conductivity modulation before the turn-off can be sufficiently suppressed by securing the width of TS. A prototyped 6.5 kV i-TASC demonstrates 45% lower E
off compared with the conventional single-gate IGBTs.
تأثير مستخلص قشور البرتقال والليمون الصناعي في نمو وحاصل نبات الشعير
Authors: ا.م.د.وفاق امجد القيسي  , م.ايمان حسين الحياني
Published: May 2023

أجريت تجربة حقلية في الحديقة النباتية لقسم علوم الحياة في كلية التربية للعلوم

الصرفة/ ابن الهيثم؛ جامعة بغداد خلال موسم النمو ‎)٢٠١٣-٢٠١٢(‏ بهدف دراسة تأثير

مستخلصي قشور البرتقال والليمون الصناعي بالتركيزين ‎١٠‏ و9670 في نمو وحاصل

نبات الشعير 70/8072 7074000700. أظهرت النتائج زيادة معنوية في ارتفاع النبات و

عدد الأوراق و عدد الاشطاء و المساحة الورقية و معدل النمو المطلق و معدل النمو

النسبي و مساحة ووزن ورقة العلم و الوزن النوعي والمساحة النوعية لورقة العلم و

طول وكثافة وزن السنبلة و وزن حبوب السنبلة و عدد ووزن السنابل و طول السفا و

دليل المحصول و كثافة محصول الحبوب و وزن الحبوب و الوزن الكلي للنبات و وزن

‎٠‏ حبة ومعامل الهجرة لجميع المعاملات مقارنة بنباتات السيطرة.
عزل لافقريات القاع في الزاب الصغير/ التون كوبري/ شمال العراق
Authors: ناديا عماد الامين
Published: May 2023

في دراسة لمجتمع لافقريات القاع في الزاب الصغيرا منطقة التون كوبري ‎١‏ شمال

العراق والمرتبطة بنبات اللبيد 67/7775 6700/7145 ,اظهرت نتائج العزل:23 فرد من

الديدان الخيطية جنس .7700/7 670070 وديدان حلقية من اجناس .م 77/0749

,. 4 , ل , ننه .1 , اضافة

للعلق .50 10550/00707000 بالاعداد 23 ,7 ,7 ,4 ,5 ,35 على التوالي . اظهرت

النتائج ان اعداد المفصليات من اجناس . 7715 ,. ح ,. ن

كانت: 95 ,119 ,21 على التوالي و 19 فرد من النواعم جنس 4906750 :776/7 ,

وكانت اعلى نسبة مئوية ل. 0100( واقل نسبة مئوية ل عل . ,

واظهرت نتائج الوفرة النسبية سيادة شعبة المفصليات بينما كانت اجناس باقي الشعب

قليلة الوفرة , وسجل كل من تركيز ايون الهيدروجين معدل( 7.1 - 7.5 ) ودرجات

الحرارة ( ‎١٩١ - ١٦‏ ) درجة مئوية اما معدل تركيز الملوحة فكان ‎-.,٤٦٢(‏

‎).,٩‏ جزء بالاف.
استخدام بعض البدائل العلاجية في تثبيط نمو بكتريا Proteus mirabilis المسببة لالتهابات المجاري البولية
Authors: زينة هاشم شهاب  , نور مهدي فاضل
Published: May 2023

تضمنت الدراسة الحالية اختبار الفعالية الحياتية الطبيعية للصبغات الكحولية و

صبغة الخل والمستخلصات المائية لاوراق النعناع الطرية فضلا عن زيت نبات النعناع

ومقارنة فعاليتها مع بعض الاحياء العلاجية مثل بكتريا حامض اللاكتيك 06140(01::1:45

] و خميرة ! حك لتقييم قدرتها على تثبيط

نمو بكتريا 771077001115 7707215 المعزولة من التهابات المجاري البولية باستخدام طريقة

الانتشار بالاقراص . وأظهرت نتائج التشخيص الكيميائي الابتدائي احتواء النبات على

المكونات الفعالة مثل القلويدات والفينو لات والتانينات والكلايكوسيدات والفلافونويدات

والكومارينات في صبغة الكحول و صبغة الخل وبنتائج اقل في المستخلص المائي ؛ وقد

تنوعت نتائج دراسة الفعالية التثبيطية للمستخلصات باختلاف نوع المستخلص نفسه

واختلاف الكائن المجهري المختبرء إذ أظهرت صبغة الخل والخل بمفرده وصبغة الكحول

فعالية اعلى في تثبيط نمو البكتريا من المستخلص المائي وزيت نبات النعناع ؛ وسجل

أعلى معدل تثبيط 29ملم ,26ملم»24ملم على التوالي مقارنة بمعدل أقطار تثبيط بكتريا

حامض اللاكتيك وخميرة السكارومايس اذ سجل أعلى منطقة تثبيط 6ملم و 3ملم على

التوالي , وهي اقل فعالية لمعدل تثبيط أقطار البكتريا باستخدام المستخلصات النباتية.
أثر التدريس العلاجي للأخطاء الشائعة في الرياضيات في تحصيل مادة العلوم لطالبات الصف الثالث في معهد اعداد المعلمات
Authors: د. انعام ابراهيم عبد الرزاق
Published: May 2023

مما لا شك فيه ان تطور العلوم بصورة عامة تعتمد على الرياضيات ويكونمصاحبا لتطورها وذلك نتيجة لتزايد اعتماد العلوم على الأساليب الرياضية ولذا فانالكشف عن الأخطاء الرياضية التي تؤثر على تحصيل الطلبة في العلوم ومعالجتها لهأهمية في نجاح الطالب وتقدمه في مادة العلوم. يهدف البحث الحالي معرفة أثر التدريس العلاجي للأخطاء الشائعة في الرياضياتفي تحصيل مادة العلوم ولأجل تحقيق ذلك وضعت الباحثة الفرضية الإحصائية الاتية:لا توجد فروق ذات دلالة إحصائية في متوسط تحصيل الطالبات في العلوم بيتالمجموعتين التجريبية والضابطة. بلغت عينة البحث ‎)٥٠(‏ طالبة يمثلن شعبتين من الصف الثالث في معهد اعدادالمعلمات / المنصور . وقد كافأت الباحثة طالبات المجموعتين في متغير تحصيلهم في الرياضيات للعامالماضي والعمر الزمني والدخل الشهري والمستوى التعليمي للوالدين. قامت الباحثة بتدريس المجموعتين بنفسها على مدى فصل دراسي كامل استخدمتالأسلوب العلاجي للأخطاء الشائعة في الرياضيات عند تدريس المجموعة التجريبية ولمتستخدمها عند تدريس المجموعة الضابطة واخذت الباحثة درجات العلوم في نهاية المدة
Desarrollo de competencias blandas en estudiantes de ingeniería: trabajo colaborativo
Authors: Alfaro Cazares Neydi Gabriela
Published: May 2023

El presente trabajo se enfoca en el desarrollo de las competencias blandas centradas en el estudiante de ingeniería, basado en el modelo de trabajo colaborativo, que actualmente es importante para los empleadores que el egresado se integre al equipo de trabajo y pueda obtener resultados favorables, para este trabajo se utilizó una metodología cuantitativa, donde se aplicó un cuestionario que permite conocer las habilidades sociales que poseen los estudiantes, el desarrollo del mismo fue en escala de Likert, se aplicó a través de una plataforma en línea, obteniendo una muestra de 530 estudiantes de licenciatura en ingeniería en una universidad del noreste en México, posteriormente se analizaron las respuestas, para posteriormente obtener como resultados que la forma de integrarse es en grupos para realizar trabajo en equipo, como conclusiones es importante que estudiante desarrolle durante su estancia en el trabajo colaborativo, porque este incluye una comunicación efectiva, negociación, empatía y liderazgo, que es una habilidad que se requiere en el mundo laboral.
JULIAN BARNSNING “DUNYO TARIXI 10 ½ BOBDA” ROMANIDAGI POSTMODERNISTIK METAPROZASI
Authors: TURSUNOVA Mukhlisa
Published: May 2023

Maqolada Britaniyaning yetakchi adiblaridan biri — Julian Barnsning “Dunyo tarixi 10 ½ bobda” romani asosida metaprozadagi adabiy va estetik pozitsiyasi ko‘rib chiqildi, u postmodernizmning o‘ziga xos adabiy va badiiy yo‘nalishi sifatida tan olingan. Postmodernistik metaprozaning zamonaviy adabiyotdagi o‘rni, uning paydo bo‘lishi va rivojlanishi, shuningdek, nazariy jihatdan tadqiqot davomida aniqlanganidek, muallif tomonidan adabiy asar yaratish jarayonida tilning meta-xususiyatlarini tanqidiy o‘rganish tahlil qilindi. Yozuvchi dunyo tarixiy bosqichlarini idrok etishi metaprozaning badiiy fragmentlariga asoslanganligi isbotlangan. Yozuvchining ushbu asari postmodernizmning parodiya, kinoya va metaprozaning stilizatsiyasi kabi ustuvor badiiy elementlariga yuzaga chiqargani ko‘rsatildi. Adabiy tahlil jarayonida yozuvchi metaprozaning adabiy strategik yo‘nalishi talablaridan kelib chiqib, borliqning so‘zma-so‘z mohiyatini anglashda asrlar davomida an’anaviy tarzda hukmronlik qilib kelgan adabiy nasrning biryoqlama yondashuvlaridan chetga chiqqani yaqqol namoyon bo‘ldi. Shuningdek, u insoniyatning adabiyot va san’atning badiiy mahoratidan foydalangan holda haqiqiy voqelikni yaratishga urinishlarini qoralaydi.
POST OPERATIVE ASTIGMATISM AFTER MANUAL SMALL INCISION CATARACT SURGERY REQUIRING SCLERAL TUNNEL SUTURING
Authors: D N Prakash , R Raghavendra , S Aswathy
Published: May 2023

Purpose: To study postoperative astigmatism after manual small incision cataract surgery (MSICS) which required scleral tunnel suturing.
Materials And Methods: This is a prospective study of 120 cataract patients attending ophthalmology out patient department from December
2021 to May 2022 who underwent MSICS which required scleral tunnel suturing. Preoperative evaluation was done. MSICS was performed in all
cases and scleral tunnel suturing was performed in these cases as there were complications like shallow anterior chamber, button hole, premature
entry, iris prolapse and posterior capsular rent. Suturing was done to stabilise sclerocorneal wound. In cases with posterior capsular rent inspite of
stable wound, suturing was done to avoid post op infections like endophthalmitis. Patients were followed up at 1week, 4 weeks, 6 weeks and 8
weeks postoperatively. Results: Out of 120 patients 72 patients (60%) had WTR astigmatism and 48 patients(40%) had ATR astigmatism
preoperatively. After 8 weeks post suture manipulation among WTR astigmatism patients 70.61% had <1 D astigmatism and among ATR patients
72.91% had <1 D astigmatism. 70% patients had BCVA6/9 or better, 25.83% had BCVAbetween 6/12 -6/24 and 4.1% had visual acuity </= 6/36.
Conclusion: Scleral tunnel suturing in MSICS results in surgically induced astigmatism. It affects the visual outcome signicantly. With optical
correction and suture manipulation, correction of astigmatism is possible. Hence scleral tunnel has to be attempted in unavoidable cases
CLINCO-MICROBIOLOGICAL PROFILE OF RHINOSINUSITIS IN ADULTS
Authors: Kawatra Rahul , Maheshwari Puneet , Agarwal Anjali , Salam Salwa
Published: May 2023

Introduction: Rhinosinusitis is the condition in which sinonasal mucosa inside the paranasal sinuses gets inamed and its clinical manifestation is represented by various sinonasal and extra-nasal symptoms. Hence, the present study was planned with an aim to study the clinic-microbial prole of rhinosinusitis in adults. This cross-sectional analytical study included 300 rhi Methodology: nosinusitis patients. Detailed clinical and demographic data were collected. All the patients underwent plain radiography to assess the sinus involvement. Nasal endoscopy was performed in all the cases. During nasal endoscopy, nasal swabs were collected from all the patients. For all the culture positive cases, antibiotic susceptibility assessment was done. The majority of cultures (61.3%) were negative for pathogens. 34% ha Results: d a positive bacterial pathogen culture, while 4.7% had a positive fungal culture. Methicillin-resistant Staphylococcus aureus (MRSA) was the most prevalent gramme-positive isolate (55.9%). Simultaneously, Citrobacter spp. (3.9%) was the most prevalent gramme-negative isolate. Candida spp. accounted for 71.4% of the fourteen positive fungal specimens, while Aspergillus avus accounted for the remaining 28.6%. The majority of patients were only administered antibiotics. Cefoperazone-Sulbactam, Linezolid, Piperacillin-tazobactam, Cefritaxeone, Tobramycin, Meropenem, and Clindamycin exhibited one hundred percent sensitivity. The three most resistant antibiotics used in more than half specimen were Tetracycline (60.7%), Erythromycin (17.4%) and Penicillin (13.7%) respectively. The most prevalent organism causing rhinosinusitis was Conclusion: found to be Staphylococcus aureus and most sensitive antibiotics were Cefoperazone-Sulbactam, Linezolid, Piperacillin-tazobactam, Cefritaxeone, Tobramycin, Meropenem, and Clindamycin.
PREVALENCE AND RISK FACTORS OF URINARY INCONTINENCE AMONG WOMEN
Authors: Bansal Sakshi , Chaudhary Deepa , Mital Premlata , Rawat Priyanka
Published: May 2023

Aim: To identify prevalence of different types of urinary incontinence and risk factors associated with them. Study Design: This was a cross sectional study conducted between March 2021 to March 2022 at outpatient department of Obstetrics and Gynaecology at SMS medical college, Jaipur. 100 women with complaint of leakage of urine were enrolled in study and data was collected as face to face interview with questionnaires. The data is expressed as mean, median, standard deviation. P values are calculated and <0.05 are considered signicant. Results: Majority of women had stress urinary incontinence (48%) followed by urge and mixed incontinence (30%,22% respectively). Majority of women were housewives (83.3%). Socioeconomic status, BMI , education status (p value- 0.001, 0.024, 0.004) were found to be signicantly associated with urinary incontinence. Age, Duration, High BMI and Higher parity was signicantly associated with severity of urinary leakage. History of UTI/ cystitis has been signicantly associated with urge incontinence (p value of 0.021) and women with history of constipation has been signicantly associated with stress incontinence (p value of 0.01). Medical disorders did not show any signicant association in the study. Conclusion: Stress urinary incontinenec is found to have the highest prevlance. Age, BMI, parity, educational status, occupation and previous infections and surgical history are various risk factors for same
A CROSS SECTIONAL STUDY ON PHANTOM VIBRATION SYNDROME AND ITS IMPACT ON PSYCHOLOGICAL MORBIDITY AMONG MEDICAL STUDENTS.
Authors: P Meshram Arzoo , Deshmukh Jyotsna , R Jadhao Ashok , Agarwal Sanjay , Mahesswaran G Uma , D Kamble Pooja
Published: May 2023

Background - Phantom vibration syndrome (PVS) is the sensation of false belief that mobile phone is vibrating when actually it is not. It is an emerging psychological disorder due to overuse of mobile phones owing to its charismatic features such as portability, accessibility, etc. Mobile phones have become an essential part of day-to-day life. As a society increasingly dependent on mobile phones, PVS easily becomes a phenomenon of worry. Frequent use of Mobile phones on prolonged vibration mode lead towards PVS. Studies suggest that PVS can cause psychological stress, anxiety, depression and if left unmanaged, primary symptoms progress to advanced stages. Aims and Objectives - To estimate the proportion of Phantom Vibration Syndrome among medical students and to assess the Impact of Phantom Vibration Syndrome on Stress, Anxiety and Depression. Materials and Methods - Across sectional online questionnaire-based study was conducted among 280 medical students of Indira Gandhi Government Medical College, Nagpur from January 2022 to February 2022. Data was collected using pre-tested questionnaire which included questionnaire regarding Mobile phone usage and Psychological well- being. Stress, Anxiety and Depression were assessed using Perceived stress scale, Hamilton Anxiety rating scale and Beck's Depression Inventory Scale respectively. Results – Out Of 280 respondents, 135 (48.2%) are Male and 145 (51.8%) are Female. 74% (208) reported having experienced Phantom Vibration Syndrome (PVS) from mobile phones. Whereas only, 18.57% of Study Participants experienced Phantom Ringing Syndrome. Conclusions – Excessive problematic usage of mobile phone has resulted in various disorders like phantom vibration syndrome, Phubbing, Ringxiety and Nomophobia that deals with psychological or socio behavioral changes. By limiting mobile phone use in a productive way, these health-related problems can be avoided.
Runtime Evolution of Bitcoin's Consensus Rules
Authors: Svennevik Notland Jakob , Nowostawski Mariusz , Li Jingyue
Published: May 2023

The manuscript has been submitted to IEEE TSE.
Blood pressure estimation from photoplethysmography by considering intra- and inter-subject variabilities: guidelines for a fair assessment
Authors: Bulhões da Silva Costa Thiago , Dias Felipe Meneguitti , Cardenas Diego Armando Cardona , Toledo Marcelo Arruda Fiuza de , Lima Daniel Mário de , Krieger José Eduardo , Antonio Gutierrez Marco
Published: May 2023

Cardiovascular diseases are the leading causes of death, and blood pressure (BP) monitoring is essential for prevention, diagnosis, assessment, and treatment. Photoplethysmography (PPG) is a low-cost opto-electronic technique for BP measurement that allows the acquisition of a modulated light signal highly correlated with BP. There are several reports of methods to estimate BP from PPG with impressive results; in this study, we demonstrate that the previous results are excessively optimistic because of their train/test split configuration. To manage this limitation, we considered intra- and inter-subject data arrangements and demonstrated how they affect the results of feature-based BP estimation algorithms (i.e., XGBoost, LightGBM, and CatBoost) and signal-based algorithms (i.e., Residual U-Net, ResNet-18, and ResNet-LSTM). Inter-subject configuration performance is inferior to intra-subject configuration performance, regardless of the model. We also showed that, using only demographic attributes (i.e., age, sex, weight, and subject index number), a regression model achieved results comparable to those obtained in an intra-subject scenario. Although limited to a public clinical database, our findings suggest that algorithms that use an intra-subject setting without a calibration strategy may be learning to identify patients and not predict BP.
Difference-Deformable Convolution with Pseudo Scale Instance Map for Cell Localization
Authors: Zhang Chengyang , Chen Jie , Li Bo , Feng Min , Yang Yongquan , Zhu Qikui , Bu Hong
Published: May 2023

Cell localization is still facing two unresolved challenges: 1) the
large variability in cell size and shape, coupled with the heterogeneous
intensity distribution of lightly stained cells, presents the bottleneck
limiting accurate cell localization; 2) existing cell location map is
unreasonable, which loses cell scale information and significantly
affects the accuracy of cell counting. To address the challenges from
the cell shape and heterogeneous intensity distribution, we propose a
novel gradient-aware and shape-adaptive Difference-Deformable
Convolution (DDConv), which can focus on the gradient information of
lightly stained cells for overcoming the challenge of heterogeneous
intensity distribution and meanwhile adaptively adjust the shape of the
convolutional kernel for overcoming the challenge of the large
variability in cell shape. Moreover, to solve the challenge of
unreasonable location map, we propose a new cell location map, called
Pseudo-Scale Instance (PSI) map. Our PSI map enables adaptively
computing the scale information and associating it with each cell’s
annotation, which addresses the unreasonable challenges in existing cell
location map and advanced makes the model sensitive to the size of
cells. We analyze and evaluate DDConv and PSI on two challenging cell
localization tasks. Compared with existing methods, our proposed method
has significantly improved the localization performance, setting a new
benchmark for cell localization tasks.
Rank-based Transformation (RBT) Algorithm for Image Contrast Adjustment
Authors: Chen Cheng-Hui , Nordling Torbjörn E. M.
Published: May 2023

Performing proper image contrast adjustment with- out information loss is an art. The default settings are often inappropriate for the image in question rendering a contrast adjustment depending on trial and error. We propose a simple method, rank-based transformation (RBT), for image contrast adjustment that requires no prior knowledge. This makes RBT an ideal first tool to apply for underexposed images. The RBT algorithm normalizes and equalizes all the intensity differences of the image over the full intensity range of the image data type, and thus assigning equal weight to all gradients. Even the state-of-the-art AI tool Cellpose visually benefits from RBT pre- processing. Our comparison of histogram normalization methods demonstrates the ability of RBT to bring out image features. 
Denoising and Completion Filters for Human Motion Software: a Survey with Code
Authors: Martini Enrico , Calanca Andrea , Bombieri Nicola
Published: May 2023

 Software platforms used for human motion analysis are increasingly being utilized in various fields, ranging from Healthcare to Industry 5.0. However, the inherent inaccuracy of these platforms often results in noisy descriptions of human poses or time periods during which the information is even missing. As a consequence, data filtering for denoising or completion is a common yet fundamental step before data analysis. Over the years, different techniques have been proposed, from generalpurpose solutions based on low-pass filters to more advanced and embedded approaches based on state observers rather than deep learning. This survey presents the current state-of-the-art filtering solutions for denoising and completing data generated by software platforms for human motion analysis, with a focus on 3D positional data extrapolated through marker-based or markerless motion capture systems. It proposes a concise taxonomy based on the filter technology and application assumptions. For each class, it summarizes the basic concepts and reports application feedback collected from literature. The survey also includes implementation codes or links to the authors’ original codes, allowing readers to easily reproduce all the algorithms in different experimental settings (https://github.com/PARCO-LAB/mocap-refinement).
High-Efficiency CMOS Charge Pump for Ultra-Low Power RF Energy Harvesting Applications
Authors: Jaymon Ashik , Mukherjee Ankur , R Sai Chandra Teja , Dutta Ashudeb
Published: May 2023

This paper explicates the design and implementation of a switch capacitor DC-DC converter system for  Radio Frequency (RF) energy harvesting applications for an input voltage in the sub-150mV range, using 180-nm CMOS triple-well BCD technology. The proposed system incorporates a charge pump architecture that employs an improvised Dynamic Gate Biasing (DGB), Forward and Reverse Body Bias technique (FRBB), along with a time axis symmetrical clocking scheme implemented using an advanced bootstrapped CMOS driver to enhance the overall drive capability of the system at low input voltages. Post-layout extracted simulations demonstrate that the proposed system achieves higher overall efficiency, delivering a peak Power Conversion Efficiency (PCE) of 85.8% at 125mV input voltage, outperforming other state-of-the-art architectures in similar voltage ranges. Moreover, the proposed system exhibits reliable operation even at input voltages as low as 85mV, while maintaining good overall efficiency.
Antibiotic sensitivity of cholera vibrions in biofilms formed on various substrates
Authors: Selyanskaya Nadezhda A. , Titova Svetlana V. , Menshikova Elena A.
Published: May 2023

Introduction. Evaluation of antibiotic sensitivity of biofilms formed by Vibrio cholerae can help in the search for effective drugs to combat cholera.
The aim of the work is to evaluate the effectiveness of antibacterial drugs against V. cholerae cells being a part of a polymicrobial biofilm formed on various substrates.
Materials and methods. Mono- and polymicrobial biofilms were simulated in vitro on chitin and plastic in flasks containing tap autoclaved water contaminated with a suspension of 104 microbial cells of three strains of V. cholerae O1 El Tor separately or in combination with Escherichia coli QD 5003.
Results. When being a part of mono- or polymicrobial bacterial communities formed by the studied strains on chitin or plastic, the V. cholerae and E. coli cells were less susceptible to the action of antibacterial drugs.
Conclusion. The increased antibiotic resistance of V. cholerae biofilms formed on biotic and abiotic surfaces highlights the danger of their spread and preservation in the environment, creates additional problems regarding the use of antibiotics and requires the development of alternative strategies to reduce resistance.
Antigenic identity of immunodominant proteins of Bacillus anthracis genovariants
Authors: Izhberdeeva Margarita P. , Sautkina Anastasiya A. , Barkova Irina A. , Viktorov Dmitry V.
Published: May 2023

Introduction. The main biological raw materials for the production of immunobiological preparations for identification of Bacillus anthracis are its specific antigens, the protective antigen and the EA1 protein.
Purpose. To determine the antigenic identity of immunodominant proteins of different genovariants of B. anthracis isolated by gel chromatography and electrophoresis.
Materials and methods. Culture filtrates of isogenic variants of B. anthracis strain 575/122 (pXO1+, pXO2+): R01 (pXO1+, pXO2); R00 (pXO1, pXO2) were used in the study. Gel chromatographic fractionation and electrophoretic separation were carried out according to standard methods. The antigenic properties of proteins isolated by gel chromatography and electrophoresis were studied by immunodiffusion with polyclonal monospecific sera against the protective antigen and the EA1 protein of the S-layer.
Results. Gel chromatographic separation of B. anthracis 575/122 culture filtrates R01 (pXO1+, pXO2) and R00 (pXO1, pXO2)yielded fractions 1 and 5. Sera against EA1 protein and antigens of fraction 1 of strains B. anthracis 575/122 R00 and B. anthracis 575/122 R01 culture filtrates identified the identical antigens. Serum against antigens of fraction 5 of B. anthracis 575/122 R01 contained antibodies to numerous proteins, including the protective antigen isolated by electrophoresis.
Discussion. The antigenic identity of immunodominant proteins isolated by gel chromatography and electrophoresis was identified.
Conclusion. EA1 and PA proteins isolated by electrophoresis and gel chromatography can be used for production of monoclonal and polyclonal monospecific antibodies suitable for the design of diagnostic preparations.
Antimicrobial resistance in foodborne Salmonella enterica isolates in the Republic of Belarus
Authors: Kulikova Nina G. , Chernyshkov Alexey V. , Mikhaylova Yuliya V. , Zenkovich Alexander L. , Dovnar Daria A. , Mareiko Ala M. , Bityumina Lyutsiya A. , Shelenkov Andrey A. , Egorova Anna E. , Saenko Stepan S. , Manzenyuk Igor N.
Published: May 2023

Introduction. Antimicrobial resistance is a global public health concern. Salmonella spp., which can be transmitted to humans through contaminated food, are among the most important foodborne pathogens worldwide.
Materials and methods. The antimicrobial resistance of 358 bacterial isolates collected from food and water in the Republic of Belarus (Belarus) in 20182021 was studied by analyzing phenotypic and genotypic characteristics of antibiotic bacterial resistance. MALDI-TOF mass spectrometry was used to classify and identify bacteria. Phenotypic antimicrobial susceptibility of bacteria was measured by the minimum inhibitory concentration method using a Sensititre automated bacteriological analyzer and the disk diffusion test for 45 antimicrobial agents. Antimicrobial resistance genes in multidrug-resistant Salmonella isolates were identified by whole-genome sequencing.
Results. The in vitro testing of phenotypic bacterial susceptibility showed high susceptibility to fluoroquinolones (97.2%), third-generation cephalosporins (93.9%), carbapenems (98.0%), ampicillin (81.8%), aminoglycosides (97.5%), tetracyclines (87.5%), chloramphenicol (93.8%), trimethoprim/sulfamethoxazole (co-trimoxazole) (95.3%) and colistin (85.2%). It was found that the antibiotic resistance mechanism in S. enterica was associated with the presence of genes blaTEM-1B (82%), blaTEM-1C (7.7%), blaSHV-12 (2.6%), blaDHA-1 (2.6%), blaCMY-2 (7.7%), qnrB2 (9.1%), qnrB4 (9.1%), qnrB5 (9.1%), qnrB19 (72.7%), aac(6)-Ib-cr (9.1%), aac(6)-Iaa (100%), aadA1 (13.2%), aadA2 (8.8%), tetB (74.3%), tetA (25.7%), tetM (2.9%), tetD (28.6%), mcr-9 (1.5%).
Conclusion. All the bacterial isolates were phenotypically susceptible to first-line antibiotics used in treatment of salmonellosis: fluoroquinolones and third-generation cephalosporins. The whole-genome sequencing of multidrug-resistant Salmonella isolates (19.0%) detected resistance genes for 9 groups of antibiotics: aminoglycosides (100%), beta-lactams (57.4%), fluoroquinolones (16.2%), tetracyclines (51.5%), macrolides (1.5%), phenicols (30.4%), trimethoprim (13.0%), sulfonamides (47.8%) and colistin (1.4%). Thus, epidemiological surveillance of the Salmonella spread through the food chain is of critical importance for the monitoring of antimicrobial resistance among foodborne Salmonella.
Developing wine tourism experiences. A discrete choice analysis using best-worst scaling data
Authors: Del Chiappa Giacomo , Martin Juan Carlos , Román Concepción
Published: May 2023

The aim of this research is to aid winery managers in bundling a plethora of different service features to meet the wine tourists’ expectations. A discrete choice model using best-worst scaling (BWS) data is estimated to obtain the relative importance of the attributes included in the analysis. Findings show that the most important aspects that make wineries attractive are: to offer wine tastings and “tour & visits”, to provide visitors with wine specialists/tour guides and, finally, to make the surrounding area and natural environment as pleasant as possible. Furthermore, the study highlights that wine tourists’ preferences are heterogeneous.
PENGARUH FASILITAS DAN KUALITAS PELAYANAN TERHADAP KEPUASAN PENGUNJUNG (Studi pada Wisata Jurang Senggani (Buper) Kecamatan Sendang Kabupaten Tulungagung)
Authors: Suyatno Rekawati , Sri Widyanti Hastuti Maria Agatha
Published: May 2023

Fasilitas merupakan segala sesuatu yang sengaja disediakan oleh penyedia jasa untuk dipakai serta dinikmati oleh konsumen yang bertujuan memberikan tingkat kepuasan yang maksimal. Jika fasilitas yang disediakan kurang maksimal maka dapat mempengaruhi kepuasan konsumen atau pengunjung. Namun bukan hanya fasilitas saja yang mempengaruhi akan tetapi kualitas pelayanan juga yang dapat mempengaruhi kepuasan konsumen atau pengunjung, karena dengan adanya pelayanan yang baik dan ramah maka para pengunjung akan terlihat sangat senang dan puas sehingga meningkatkan daya tarik tersendiri. Penelitian ini bertujuan untuk mengetahui pengaruh fasilitas dan kualitas pelayanan terhadap kepuasan pengunjung wisata Jurang Senggani (Buper) Kecamatan Sendang Kabupaten Tulungagung. Jenis penelitian merupakan jenis penelitian kuantitatif. Metode pengumpulan data yang digunakan dalam penelitian ini adalah angket (kuensioner) dan analisis data menggunakan regresi linier berganda. Hasil penelitian menunjukkan bahwa fasilitas secara parsial berpengaruh positif dan signifikan terhadap kepuasan pengunjung dengan nilai thitung > ttabel yaitu 8,655 > 1,9690. Kualitas Pelayanan secara parsial berpengaruh positif dan signifikan terhadap kepuasan pengunjung dengan nilai thitung > ttabel yaitu 7,918 > 1,9690. Fasilitas dan Kualitas Pelayanan secara simultan berpengaruh positif dan signfikan terhadap kepuasan pengunjung dengan nilai Fhitung > Ftabel yaitu 827,359 > 3,031918.
PENGARUH KEUNIKAN PESAN IKLAN DAN BRAND IMAGE TERHADAP PENGAMBILAN KEPUTUSAN PEMBELIAN KONSUMEN PASTA GIGI PEPSODENT DI DESA PATUMBAK KAMPUNG
Authors: ANA SRI AFRILIANA , Safina Wan Dian
Published: May 2023

Penelitian ini bertujuan untuk menguji Pengaruh Keunikan Pesan Iklan Dan Brand Image Terhadap Pengambilan Keputusan Pembelian Konsumen Pasta Gigi Pepsodent Di Desa Patumbak Kampung. Metode yang digunakan adalah kuantitatif. Populasi dalam penelitian ini masyarakat Desa Patumbak Kampung berjumlah 300 orang, dengan pengambilan sampel menggunakan rumus slovin sebanyak 75 sampel. Nilai koefisien untuk variabel Keunikan Pesan Iklan (X1) sebesar 0,685 dimana nilai t-hitung 9,974 > t-tabel 1,993 dan signifikan sebesar 0,000 < 0,05 artinya H0 ditolak dan Ha diterima dapat dinyatakan bahwa variabel Keunikan Pesan Iklan (X1) berpengaruh positif dan signifikan terhadap Keputusan Pembelian Konsumen pasta gigi pepsodent. Nilai koefisien untuk variabel Brand Image (X2) sebesar 0,286 dimana nilai t-hitung 4,165 > t-tabel 1,993 dan signifikan sebesar 0,000 < 0,05 yang artinya H0 ditolak dan Ha diterima, dinyatakan bahwa variabel Brand Image (X2) berpengaruh positif dan signifikan terhadap Keputusan Pembelian Konsumen. Nilai F hitung sebesar 155,670 > F tabel 3,12 dengan nilai sig. 0,000 < 0,05, yang artinya hasil uji F membuktikan Keunikan Pesan Iklan (X1) dan Brand image (X2) secara simultan berpengaruh positif dan signifikan terhadap keputusan pembelian (Y). Selanjutnya Nilai Adjusted R Square 0,807 yang berarti hubungan variabel Keunikan Pesan Iklan dan Brand Image terhadap keputusan pembelian sebesar 80,7%
Analysis of the diagnostic utility of Glasgow-Blatcford Score, Rockall Score, AIMS65 Score, BUN-to-albumin ratio and BUN-to-creatinine ratio for predicting the need for transfusion in upper gastrointestinal bleeding
Authors: Yurttaş Tahir Talat , Yılmaz Sarper , Cander Başar
Published: May 2023

Objective: This study aimed to compare the predictive accuracy of commonly used risk scores in predicting the need for transfusion among patients with upper gastrointestinal bleeding (UGIB).
Material and Methods: This retrospective diagnostic utility study was conducted at a tertiary care academic hospital. The primary outcome was the diagnostic accuracy of the Glasgow-Blatchford Score (GBS), the Rockall Score, the AIMS65 Score, the BUN-to-albumin ratio (BAR), and the BUN-to-creatinine ratio (BCR) in the prediction of transfusion in UGIB.
Results: Results from the study showed that 75% of the 104 patients included in the study received blood transfusions, with a median of 3 (IQR 2 - 4) units. Admission hemoglobin and hematocrit values were higher in the non-transfusion group (p<0.001 for both comparisons). The GBS (AUC 0.790 [95% CI 0.699 - 0.864]; p<0.001), AIMS65 (AUC 0.672 [95% CI 0.573 - 0.761]; p=0.001), and BAR (AUC 0.625 [95% CI 0.525 - 0.718, p=0.04) were found to be useful diagnostic indices in predicting transfusion administration, with ideal cut-offs of >0, >10.75, and >0, respectively. But Rockall and BCR were not found to be useful diagnostically. The study suggests that these indices can be used as decision tools for transfusion administration in patients with acute upper gastrointestinal bleeding.
Conclusion: The GBS demonstrated superior accuracy compared to AIMS65 and BAR, while Rockall score and BCR were found to be ineffective. The GBS may therefore be useful to clinicians when assessing the potential need for blood transfusions in patients with UGIB.
The Effect of Vaccines and Booster Doses on Disease Progression and Mortality in Inpatients with COVID-19
Authors: GÜZEL Efraim , BAYDAR TOPRAK Oya
Published: May 2023

Objective: As of the first months of 2020, vaccination is the most effective method to combat the COVID-19 pandemic, which has become a part of our lives. This study aims to describe the vaccination status of inpatients, the effectiveness of booster vaccine protocols, and the risk factors for intensive care unit (ICU) and mortality of COVID-19 patients.

Materials and Methods: Our study included 247 patients hospitalized in a tertiary care hospital due to COVID-19. Patients hospitalized for non-COVID-19 reasons were excluded from the study even if the PCR test was positive. Socio-demographic data, clinical and laboratory findings of the participants were recorded using the hospital database and a questionnaire. Patients were divided into groups as mild-moderate-severe disease in terms of disease severity, ward and ICU in terms of hospitalization clinic. According to vaccination status, they were categorized as unvaccinated, Sinovac-based protocols, BioNTech-based protocols and others.

Results: Of the 247 patients in the study, 55.1% were male and the mean age was 60 ± 17.26 years. 38.5% of the patients were admitted to the ICU and 9.3% died. It was observed that 38.8% of those admitted to the ICU and 56.5% of those who died were not vaccinated. Being over 65 years of age (p=0.008), being hospitalized for more than 7 days (p=0.003), having a severe illness (p=0.002), having a nervous system disease (p=0.005) and having other comorbidities (p=0.000), were significant for ICU admission, whereas disease severity (p=0.000) and comorbidities such as hypertension (p=0.000), diabetes mellitus (p=0.020) and cardiovascular diseases (p=0.000) were found to be risk factors for mortality.

Conclusion: The addition of reminder doses, especially the fourth dose, to vaccination protocols may be more beneficial in preventing the need for ICU follow-up, which increases mortality in COVID-19.
Effect of smooth eye tracking in different patterns on results of the modified Clinical Balance Sensory Integration Test in healthy young adults
Authors: Ferenc Aneta , Wójtowicz Sebastian , Łakoma Aleksandra , Daniluk Anna , Wiaderna Karolina , Hadamus Anna
Published: May 2023

Purpose: The aim of the study was to determine whether eye tracking of a point moving in different directions influences balance test performance in young healthy subjects. Methods: The study enrolled 45 healthy young adults aged 19–26. Balance assessment was carried out according to the modified Clinical Balance Sensory Integration Test protocol using the Biodex Balance System with an additional 63” screen to present the eye-tracking task. Each participant repeated measurements in standing on a stable and foam surface in six test conditions: two without eye tracking with eyes open and eyes closed, and four with eye tracking: with vertical, horizontal, star, and circle moving point. Each trial lasted 30 sec. Results: Regression analysis for the Sway Index showed that there was no impact of eye tracking on test results (p = 0.4326), although detailed analysis showed a significant impact of tracking a point moving in a circle in standing on a foam surface (p < 0.001). Conclusions: The presented results show that eye-tracking does not influence the results of the balance test with exception of eye-tracking of the circle movement in standing on a foam surface. It suggests that eye movements may affect the test results when performing more difficult balance tests.
Characteristic research of lower extremity injuries in elderly pedestrians during collisions
Authors: Sen Xiao  , Lidong Zhang  , Jindong Wu  , Xinran Liu  , Xiaoang Liu  , Hao Zhang
Published: May 2023

Purpose: The aim of this research is to study the trend of pedestrian lower extremity injuries during vehicle-pedestrian collisions. Methods: In this study, pedestrian’s age, collision angle and pedestrian’s position are considered influencing factors. Nine experiments using a novel lower extremity mechanical model are designed with the orthogonal experiment method. Results: Under the same collision angle, collisions in the left and right positions caused more serious tibia injuries than the middle position. As for the collision angle, the tibial injury at +45° is more significant than the tibial injury at −45°, and the injury of oblique collisions is slightly greater than that at 0°. Moreover, tibial injury is more sensitive to research variables than femoral injury. When the collision angle and position are changed, the difference ratio of tibia stress is by 483.2% higher than that of femur stress. The axial force and bending moment of the quadriceps tendon in the left-position collision reach peak values, which are 3.83 kN and 165.98 Nm, respectively. The peak quadriceps tendon axial force is captured with the collision angle of −45°, and the peak quadriceps tendon bending moment is obtained with a collision angle of +45°. Conclusions: The effects of differences in impact position and angle on lower extremity injury in the elderly were analyzed, and the results of this study can be used as a reference for research on lower extremity protection
Implementation of the Fair Use Defense Doctrine and Minimum Standards Principle in Copyright Dispute Settlement
Authors: Simbolon Putu George Matthew
Published: May 2023

This study aims to examine and analyze how disputes arising from copyright infringement can be resolved by applying the fair use defense doctrine in the copyright protection regime in Indonesia. This study uses normative legal research with the statute, conceptual, case, and comparative approaches. The collected legal material is then qualitatively analyzed to describe the problem and answer study purposes. The results show that Indonesia must apply the doctrine of fair use defense as a mechanism in copyright dispute settlement. Despite its unfamiliarity in Indonesia, the fair use defense aligns with the principle of minimum standards and the FET principle regulated in the TRIPs Agreement. This agreement binds Indonesia under Law Number 7 of 1994. The proportionality of this doctrine has also been tested through legal findings by the U.S. Supreme Court, which is based on Section 107 of the U.S. Copyright Act. Therefore, it is recommended that the House of Representatives amend Law Number 28 of 2014 to include more specific clauses explaining what factors qualify as fair use. In addition to amending Law Number 28 of 2014, it is recommended that the Government or the Supreme Court establish implementing regulations for Law Number 28 of 2014 concerning factors that qualify as fair use of copyrighted works. On the other hand, researchers and academics are encouraged to conduct further research on applying the fair use defense doctrine. This research can also provide valuable recommendations for the Government and the House of Representatives in strengthening Indonesia’s legal framework and copyright protection regime.
Unveiling the Value of Competitive Intelligence: Coordinated Communication and Added Value
Authors: Cekuls Andrejs
Published: May 2023

Recently, a lot of attention has been paid to several aspects of CI, which influence the decision-making of organizations and the acquisition of competitive advantages. Organizations must leverage data, artificial intelligence (AI), and social capital to enhance their competitive intelligence processes. Social media data, AI and machine learning, big data analytics, dynamic capabilities, and intraorganizational social capital all play significant roles in driving strategic decision-making and improving customer experiences. By integrating these elements effectively, organizations can gain valuable insights, mitigate risks, and stay ahead of the competition.