bluuebunny/crossref_metadata_2025 huggingface dataset:
The effects of endogenous FSH and its receptor on oogenesis and folliculogenesis in female Alligator sinensis
Authors: Nie Haitao , Xu Yunlu , Zhang Yuqian , Wen Yue , Zhan Jixiang , Xia Yong , Zhou Yongkang , Wang Renping , Wu Xiaobing
Published: July 2023

Background

The precise mechanisms of hormone action responsible for the full course of events modulating folliculogenesis in crocodilian have not been determined, although histological features have been identified.

Results

TheAlligator sinensisovarian morphological characteristics observed at 1, 15, 30, 60, 90, and 300 days post hatching(dph) revealed that the dynamic changes in germ cells varied in different meiotic and developmental stages, confirming that the processes of folliculogenesis were protracted and asynchronous. The presence of endogenous follicle-stimulating hormone(FSH) mRNA and protein expression within the cerebrum at 1 dph, in parallel with the increase in germ cells within the germ cell nests(Nest) from 1 dph to 15 dph, suggested that endocrine regulation of the pituitary-gonad axis is an early event in oogonia division. Furthermore, the endogenous expression of FSH showed a trend of negative feedback augmentation accompanied by the exhaustion of maternal yolk E2observed at 15 dph. Such significant elevation of endogenous FSH levels was observed to be related to pivotal events in the transition from mitosis to meiosis, as reflected by the proportion of oogonia during premeiosis interphase, with endogenous FSH levels reaching a peak at the earliest time step of 1 dph. In addition, the simultaneous upregulation of premeiotic markerSTRA8mRNA expression and the increase in endogenous FSH further verified the above speculation. The strongly FSHr-positive label in the oocytes within Pre-previtellogenic follicles was synchronized with the significant elevation of ovarian cAMP detected at 300 dph, which suggested that diplotene arrest maintenance during early vitellogenesis might be FSH dependent. In addition, preferential selection in asynchronous meiotic initiation has been supposed to act on somatic supportive cells and not directly on germ cells via regulation of FSH that in turn affects downstream estrogen levels. This suggestion was verified by the reciprocal stimulating effect of FSH and E2on the accelerated meiotic markerSYCP3and by the inhibited cell apoptosis demonstrated in ovarian cell culture in vitro.

Conclusion

The corresponding results contribute an expansion of the understanding of physiological processes and shed some light on the specific factors responsible for gonadotropin function in the early folliculogenesis of crocodilians.
Taste of asean: traditional food images from Southeast Asian countries
Authors: Putra Fajar Kusnadi Kusumah , Putra Mandradhitya Kusuma , Novianti Selvi
Published: July 2023

Gastronomy tourism and local food have become a powerful tool for tourism advertising because gastronomy often reflects the cultural identity of the destination. Local food images can help showcase the unique flavors of a particular region, making it more attractive to potential visitors. This study aims to analyze how regional tourism authorities share information about the diversity of traditional foods, promote gastronomic tourism, and enhance destinations' competitiveness by utilizing Instagram as a social media platform combining images with textual information. The ASEAN Tourism Online objectives are to promote the region as a single destination, increase tourism arrivals and receipts, and enhance regional connection. In this study, the official account of Southeast Asia Tourism on Instagram @visitsoutheastasiaofficial with keywords Taste of ASEAN marketing campaign. A qualitative approach using content analysis was used in this study. Data for this study were retrieved from 123 traditional food images posted on the official Instagram account from 2016 to 2022. A thematic analysis was used to classify themes. The findings presented categories ranging from the authenticity of traditional food, social media campaigns and promotions, local destination information, and gastronomic tourism activities. The majority of images posted related to the portrait of local cuisines. This analysis portrayed how the ASEAN tourism online wants to promote food as an attraction instead of food as a supporting element of tourism activities. The limitation of this study is only focused on the content of traditional visual food on the Instagram platform. Further research can be done using other social media platforms and comparing these findings with other destinations. It also provides an opportunity to gain insights into what people are saying about each destination, which can be helpful in terms of understanding customer preferences and opinions. The implication of this study will help national tourism organizations, culinary practitioners and academicians about the traditional food images on the social media platform to promote regional and city tourism. Additionally, it can help to identify potential opportunities for improvement or expansion within the region. Finally, researching other destinations through social media platforms can provide valuable information that could be used to create effective marketing strategies and campaigns.
Ultrasound findings to predict failure of conservative treatment in the appendix testis torsion
Authors: Salvo Neil Di , Parente Giovanni , Benivegna Dario , Di Mitri Marco , Thomas Eduje , Lima Mario
Published: July 2023

Background

Torsion of the appendix testis (TAT) is considered the most common cause of acute scrotum in childhood. When clinical and ultrasound (US) findings agree with the diagnosis, after testicular torsion has been excluded, conservative therapy is attempted whereas scrotal exploration and removal of the hydatid are required when medical therapy has failed. We hypothesized there are US features that can predict the failure of conservative therapy.

Methods

We conducted a retrospective analysis on pediatric patients treated for TAT. The age of patients, number of days spent with symptoms before the start of treatment, presence of epididymitis and/or hydrocele, and dimension of the twisted hydatid were analyzed. A search for a correlation between these variables and failure of conservative treatment was conducted.

Results

Patients were divided into 2 groups based on the efficacy of conservative management: responders (group I) and non-responders subjected to surgical treatment (group II). No statistically significant differences were registered in regard to age (p = 0.25), average dimension of hydatid (p = 0.09), and time gap between symptoms and the start of therapy (p = 0.92) between the 2 groups. An associated epididymitis was described in 27.5% of patients in group I and 41.7% in group II (p = 0.03; OR 1.89), and associated hydrocele was described in 33.4% of patients in group I and 45.8% in group II (p = 0.03; OR 1.83). Considering the odds ratios, the probability of surgical intervention when presenting only epididymitis without hydrocele is estimated to be 15%, when presenting only hydrocele without epididymitis: 9%, with both epididymitis and hydrocele: 74%, and without epididymitis nor hydrocele: 2%.

Conclusions

The presence of both epididymitis and hydrocele at first US evaluation is associated with a high probability of conservative treatment failure, thus predicting the need for surgical intervention.
Lymphangiography and lymphatic embolisation for the treatment of chyle leaks after neck surgery: assessment of lymphangiography findings and embolisation techniques
Authors: Kim Jinoo , Bang Dong Ho , Choi Tae Won , Won Je Hwan , Kwon Yohan
Published: July 2023

Objective:

To assess lymphangiography findings and outcome of lymphatic embolisation to manage chyle leak after neck surgery.

Methods:

Consecutive cases of lymphangiography performed between April 2018 and May 2022 for management of chyle leaks related to neck surgery were retrospectively reviewed. Lymphangiography findings, techniques, and outcomes were analysed.

Results:

Eight patients (mean age: 46.5 years) were included. Six patients had undergone radical neck dissection for thyroid cancer, and two had undergone lymph node excision. Clinical presentations were: chyle drainage through Jackson Pratt catheters in five patients, lymphorrhea through surgical wounds in two, and enlarging lymphocele in one. Lymphangiography techniques included: inguinal lymphangiography in four patients, retrograde lymphangiography in three, and transcervical lymphangiography in one. Lymphangiography revealed leaks in the terminal thoracic duct in two patients, bronchomediastinal trunk in two, jugular trunk in three, and superficial neck channels in one. Embolisation techniques included: non-selective embolisation of terminal thoracic duct (n = 2), selective embolisation of the jugular trunk (n = 3), selective embolisation of the bronchomediastinal trunk (n = 2), and intranodal glue embolisation of superficial neck channels (n = 1). One patient underwent a repeat procedure. Chyle leak resolved in all patients over a mean of 4.6 days. No complication was encountered.

Conclusion:

Lymphatic embolisation seems to be effective and safe in managing chyle leaks after neck surgery. Lymphangiography allowed for the categorisation of chyle leaks according to their location. Post-embolisation patency of the thoracic duct may be preserved in chyle leaks that do not directly involve the thoracic duct.

Advances in knowledge:

Lymphatic embolisation is safe and effective in managing chyle leaks after neck surgery. On lymphangiography, the location of contrast media extravasation may not be consistent. The technique for embolisation should be based on the location of the leak. Post-embolisation patency of the thoracic duct may be preserved in chyle leaks that do not directly involve the thoracic duct.
The diagnostic value of quantitative assessment of MR neurography in chronic inflammatory demyelinating polyradiculoneuropathy: a systematic review and meta-analysis
Authors: Chen Haofeng , Huang Xinyue , Bao Yifang , Zhao Chongbo , Lin Jie
Published: July 2023

Objectives:

The purpose of this study was to evaluate the diagnostic value of quantitative magnetic resonance neurography (MRN) in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We also compared various MRN parameters and determined the best performing one.

Methods:

Through literature searches in PubMed, Embase, Cochrane, Ovid MEDLINE and ClinicalTtrials.gov until March 1, 2023, we selected studies with the diagnostic performance of MRN in CIDP patients. The pooled estimated sensitivity and specificity of quantitative MRN parameters were determined by a bivariate random-effects model. Subgroup analysis was performed to evaluate the proper quantitative parameters and nerve sites.

Results:

A total of 14 quantitative MRN studies with 23 results gave a pooled sensitivity of 0.73 (95% CI 0.66–0.79) and a pooled specificity of 0.89 (95% CI 0.84–0.92). The area under the curve (AUC) was 0.89 (95%CI 0.86–0.92). Subgroup analysis of quantitative parameters showed the fractional anisotropy (FA) with the highest sensitivity of 0.85 (95% CI 0.77–0.90) and cross-sectional area (CSA) with the highest specificity of 0.95 (95% CI 0.85–0.99). The pooled correlation coefficient for interobserver agreements was 0.90 (95%CI 0.82–0.95).

Conclusion:

Quantitative MRN has considerable diagnostic value in CIDP patients with accuracy and reliability. FA and CSA can be promising parameters in the future diagnosis of CIDP patients.

Advances in knowledge:

This is the first meta-analysis of quantitative MRN in the diagnosis of CIDP.We have selected reliable parameters with cut-off value and provided new insights for subsequent diagnosis of CIDP.
Leprosy bacilloscopy notifications in the Brazilian Unified Health System and COVID-19 pandemic: an ecological investigation
Authors: Barbosa-Lima Ricardo , Ramos-Silva Flávia Freire , Santos José Cleyton de Oliveira , Santos Dayane Ketlyn da Cunha , Silva Glebson Moura , Kameo Simone Yuriko
Published: July 2023

Objective: to evaluate leprosy bacilloscopy exam notifications in the Brazilian Unified Health System (SUS) from April 2018 to March 2022. Methods: an ecological study was carried out using open-access data from the SUS. Results: the temporal tendency of leprosy bacilloscopy was considered significantly decrease over time (p <0.05), as well as there was a significant decrease in the first and second pandemic years when compared to the control interval in all Brazilian regions (p <0.05). Conclusion: leprosy bacilloscopy exams remain negatively affected by the COVID-19 pandemic in the SUS.
Prevalence of frailty, pre-frailty and geriatric syndromes in pe-ople aged 60 or more that use the Cofrentes spa: a pilot study
Authors: Vela María Lorena , Michan-Doña Alfredo , Pini Valentina , Fernandez-Porta Clara , Antonio De Gracia Jose , Fernandez-Toran Miguel Angel , Maraver Francisco
Published: July 2023

A longevity and balneotherapy treatment program has been initiated at the Cofrentes Medical Spa, including the development of the Rosita Longevity App. The objective of this study is to determine the health profiles (degree of frailty and pre-frailty) by means of Fried Frailty Phenotype questionnaire and the prevalence of geriatric syndromes in people over 60 doing balneotherapy at the spa, considering that the thermal environment is an ideal place to treat these types of syndromes and to delay their progress. Thermal/spa facilities often receive older patients with osteo-articular and musculoskeletal conditions. To assess the grade of the functionality, quality of life, depression, nutritional risk, cognitive state, insomnia, and the risk of falls, specific questionnaires were used. Out of a total of 43 participants, 30 were women (69.7%), and 22 older than 70 y (51.1%). There were 2 frail (4.6%) and 20 prefrail (46.5%). Conclusions: more than half of the people older than 60 who visit the Cofrentes spa present a functionality deficit condition. Women present a lower quality of life than men. The more affected items in the prefrail population were grip strength and physical activity. Health Resort Medicine is an ideal place to detect these aspects.
Is LASER therapy a viable option for increasing implant stability in bone tissue?
Authors: Popa Theodor , Negrutiu Mircea , Gherman Luciana Madalina , Dogaru Gabriela , Irsay Laszlo , Ciubean Alina Deniza , Ciortea Viorela Mihaela , Cosma Dan Ionut
Published: July 2023

Fractures can occur at any age, but in modern times as the worldwide population grows older, the risk increases. Many of the fractures need metallic implants for a more efficient healing process and a reduced risk of complications. An implant can be used in orthopedic surgery if it can safely interact with the bone and the surrounding tissue. The most used materials in fracture management are metal alloys (Steel, Titanium, Cobalt-Chrome) that need to be compatible with tissue, however, they do not stimulate the healing process. Physiotherapy could improve the bone/implant interaction by stimulating the local metabolism and cell proliferation while also reducing local symptoms such as pain. The advantages of using LASER therapy are: a reduced number of contraindications, the availability of the equipment in rehabilitation facilities, and the compliance of patients as there is no discomfort during the procedure. The main drawback of using LASERs in bone stimulation is that there is no consensus in protocol usage between researchers because of the multitude of parameters. Through this article, we aim to shed some light on the use of LASER therapy in implant osseointegration and bone healing.
Keywords: implant osseointegration, implant stability, Low-level LASER therapy, Photobio-modulation, Physiotherapy, bone
Assessment of jaw muscles and cervical spine muscles isometric force using a hand-held dynamometer in young adults
Authors: Onofrei Roxana Ramona , Amaricai Elena
Published: July 2023

Our study aims to investigate the jaw and cervical spine muscle isometric forces in healthy young adults. Fifty-four subjects (21.2 ± 4.82 years) met the inclusion criteria and agreed to par-ticipate in the study. Muscle forces were assessed with a hand-held dynamometer. A significant positive correlation was found between jaw opening forces and cervical flexors forces (r=0.62, p0.0001) and between lateral mandible deviation forces and cervical spine lateral flexion forces, both for right and left side (r=0.65, p<0.0001; r=0.69, p<0.0001, respectively. In healthy young adults, using a hand-held dynamometer for muscle strength testing, significant positive correla-tion was found between jaw opening forces and cervical flexors forces and between lateral mo-uth deviation force and cervical spine lateral flexion forces, both for right and left side. The rela-tionship between jaw muscles forces and cervical spine muscles forces is a topic that needs to be further studied, also together with posture and balance.
Keywords: Jaw muscles, cervical spine muscles, force, assessment, young adults
POEMS syndrome misdiagnosed as CIDP: A case report
Authors: Văcăraș Vitalie , Asaftei Aida , Drăghici Nicu Cătălin , Zdrenghea Mihnea , Mureșanu Dafin Fior
Published: July 2023

POEMS syndrome is a paraneoplastic disorder manifested by peripheral neuropathy and monoclonal plasma cell dyscrasia. Due to its clinical and electrophysiological aspect, POEMS syndrome is often mistaken as a chronic inflammatory demyelinating polyneuropathy (CIDP) [1]. Its acronym is derived from its principal characteristics: polyneuropathy, organomegaly, endocrinopathy, M proteins, and skin changes [2]. The purpose of this paper is to present the case of a patient who was lately diagnosed with POEMS syndrome after he was mistreated for CIDP in order to show the importance of a complete physical examination.
Keywords: POEMS syndrome, demyelinating polyneuropathy, monoclonal plasma cell disorder, skin changes, vascular endothelial growth factor.
Medical management and rehabilitation in a patient with avascular necrosis of the femoral head in the context of vitamin D deficiency and secondary hyperparathyroidism – case report
Authors: Diaconu Cosmina , Cipăian Remus Calin , Iliescu Mădălina Gabriela , Ciortea Viorela-Mihaela , Irsay Laszlo , Ungur Rodica Ana , Diaconu Cristinel Gabriel
Published: July 2023

Vitamin D is essential in determining bone and muscle health. Vitamin D deficiency (VDD) produces secondary hyperparathyroidism, loss of bone quality and mass, mineral-ization effects and fractures, myopathy, and falls. The avascular necrosis (AVN) of the femoral head pathophysiology is still unclear and can be considered a vascular bone dis-ease. Our paper aimed to evaluate the etiology of AVN in a young male with bilateral fem-oral neck damage who required bilateral arthroplasty. Method: We present the case of a 46-year-old male patient with VDD and bilateral total hip arthroplasty for osteoarthritis secondary to AVN of the femoral head. After complete hormonal, biological, and imaging evaluations, the diagnosis of primary hyperparathyroidism was not supported; the im-provement of vitamin D deficiency after eight months of treatment clarified the diagnosis: hyperparathyroidism secondary to vitamin D deficiency. Results: Supplementation with 4000 IU of vitamin D improved the patient’s response to specific rehabilitation methods. Conclusions: Severe vitamin D deficiency can secondarily affect the structure of the femoral head through secondary hyperparathyroidism, producing AVN, but only osteopenia was obtained on DXA evaluation. VDD can be an important etiological factor in the occur-rence of AVN, and its correction can improve the evolution of the disease, improving the reabilitation of these patients.
Keywords: avascular necrosis, secondary hyperparathyroidism, vitamin D deficiency, rehabilitation
Μελέτη της καρκινογένεσης του μαστού στον ελληνικό πληθυσμό μέσω μοριακής διερεύνησης της λοίμωξης από τον ιό των ανθρωπίνων θηλωμάτων σε κυτταρολογικό υλικό
Authors: Μαρέτη Ευαγγελία
Published: July 2023

Ο ιός των ανθρωπίνων θηλωμάτων (HPV), εκτός από τη γνωστή κλινική συμβολή του στον καρκίνο του τραχήλου της μήτρας, πιθανώς συμμετέχει ενεργά στην ανάπτυξη όγκων του μαστού σε διάφορους πληθυσμούς ανά τον κόσμο. Οι επικρατούντες τύποι HPV σε ασθενείς με καρκίνο του μαστού ποικίλλουν γεωγραφικά. Η παρούσα μελέτη εξετάζει περαιτέρω τη συχνότητα εμφάνισης του HPV στην Ελλάδα, με βάση τη μοριακή ανάλυση κλινικών κυτταρολογικών δειγμάτων. Δείγματα FNA βιοψίας συλλέχθηκαν από 114 γυναίκες ασθενείς, που διαγνώστηκαν μεταξύ των ετών 2018 και 2021, 57 με διαγνωσμένες βλάβες καρκίνου του μαστού C5 και 57 με καλοήθεις παθήσεις του μαστού C2. Τα δείγματα εξετάστηκαν με τη χρήση τεχνικών RT-PCR και ανοσοϊστοχημείας. Εντός του δείγματος των ασθενών ταυτοποιήθηκαν συνολικά τρεις διαφορετικοί τύποι HPV. Ο HPV 39 βρέθηκε μόνο στην ομάδα ελέγχου, στο 1,8% των ασθενών, ενώ ο HPV 59 ήταν παρών τόσο στην ομάδα ελέγχου όσο και στην ομάδα μελέτης σε ποσοστό 1,8% και 3,5%, αντίστοιχα. Από την άλλη πλευρά, ο HPV 16 ήταν παρών μόνο στην ομάδα μελέτης στο 12,3% των περιπτώσεων. Η παρουσία των διαφορετικών τύπων HPV διαφοροποιήθηκε στατιστικά μεταξύ των ιστολογικών ομάδων. Ο HPV 16 ήταν αποκλειστικά σε ενδοπορικά καρκινώματα του μαστού, ο HPV 39 ήταν παρών σε ένα δείγμα με διάγνωση κύστης και ο HPV 59 ήταν παρών σε 3 δείγματα που περιλάμβαναν ινοαδένωμα, ενδοπορικό καρκίνωμα του μαστού και διάγνωση λοβιακού καρκινώματος του μαστού. Απαιτούνται περισσότερες διεθνείς συγκριτικές μελέτες για τη διερεύνηση των πληθυσμιακών διαφορών και της κατανομής των γονότυπων του HPV και για να δοθούν σαφείς απαντήσεις σχετικά με την επίδραση που μπορεί να έχουν ορισμένοι τύποι HPV στον καρκίνο του μαστού, όπως υποστηρίζει και η παρούσα μελέτη, αν και σε ρόλο συμπαράγοντα.
Heterogenous transmission and seroprevalence of SARS-CoV-2 in two demographically diverse populations with low vaccination uptake in Kenya, March and June 2021
Authors: Munywoki Patrick K. , Bigogo Godfrey , Nasimiyu Carolyne , Ouma Alice , Aol George , Oduor Clifford O. , Rono Samuel , Auko Joshua , Agogo George O. , Njoroge Ruth , Oketch Dismas , Odhiambo Dennis , Odeyo Victor W. , Kikwai Gilbert , Onyango Clayton , Juma Bonventure , Hunsperger Elizabeth , Lidechi Shirley , Ochieng Caroline Apondi , Lo Terrence Q. , Munyua Peninah , Herman-Roloff Amy
Published: July 2023

Background: SARS-CoV-2 has extensively spread in cities and rural communities, and studies are needed to quantify exposure in the population. We report seroprevalence of SARS-CoV-2 in two well-characterized populations in Kenya at two time points. These data inform the design and delivery of public health mitigation measures.

Methods: Leveraging on existing population based infectious disease surveillance (PBIDS) in two demographically diverse settings, a rural site in western Kenya in Asembo, Siaya County, and an urban informal settlement in Kibera, Nairobi County, we set up a longitudinal cohort of randomly selected households with serial sampling of all consenting household members in March and June 2021. Both sites included 1,794 and 1,638 participants in March and June 2021, respectively. Individual seroprevalence of SARS-CoV-2 antibodies was expressed as a percentage of the seropositive among the individuals tested, accounting for household clustering and weighted by the PBIDS age and sex distribution.

Results: Overall weighted individual seroprevalence increased from 56.2% (95%CI: 52.1, 60.2%) in March 2021 to 63.9% (95%CI: 59.5, 68.0%) in June 2021 in Kibera. For Asembo, the seroprevalence almost doubled from 26.0% (95%CI: 22.4, 30.0%) in March 2021 to 48.7% (95%CI: 44.3, 53.2%) in July 2021. Seroprevalence was highly heterogeneous by age and geography in these populations—higher seroprevalence was observed in the urban informal settlement (compared to the rural setting), and children aged <10 years had the lowest seroprevalence in both sites. Only 1.2% and 1.6% of the study participants reported receipt of at least one dose of the COVID-19 vaccine by the second round of serosurvey—none by the first round.

Conclusions: In these two populations, SARS-CoV-2 seroprevalence increased rapidly in the first 16 months of the COVID-19 pandemic in Kenya. It is important to prioritize additional mitigation measures, such as vaccine distribution, in crowded and low socioeconomic settings.
EMPLOYEE RESPONSIBILITY AS A HUMAN RESOURCE MANAGEMENT OBJECT: COMPARATIVE ANALYSIS OF CHINESE AND RUSSIAN APPROACHES
Authors: Fedorova A. , Ma Cyuan'chao
Published: July 2023

The paper presents the results of a desk study of the responsibility at work, the purpose of which is to determine the degree of relevance of personnel responsibility issues, to identify the prevailing perception stereotypes of the responsibility by Chinese and Russian employees. The collection and processing of empirical data was carried out using the methods of quantitative and qualitative content analysis of text arrays in the Internet Chinese and Russian segments. An online survey of Russian enterprises’ employees involved in the poll using the spontaneous sampling method allowed the authors to identify the respondents attitude to the problem under study, as well as comparison of the Chinese and Russian employees’ narratives analysis results has practical importance for finding effective methods and tools for educating responsible employees, developed on the best practices basis. One of the key conclusions based on the study results is the disproportion between the degree of Russian specialists’ attention to the issues of personnel responsibility management and the significance of the influence of the employee responsibility factor on the organization’s performance indicators.
OPERATIONALIZATION OF PROFESSIONAL BURNOUT OF STAFF IN CONDITIONS OF REMOTE WORK AND HYBRID OFFICE
Authors: Chulanova Oksana , Sanaykov V.
Published: July 2023

The article presents the results of the author’s research on the risks of staff burnout in a remote and hybrid office. The object of the study is professional burnout in the conditions of remote work and hybrid office. The subject of the study is recommendations for the prevention of professional burnout in conditions of remote work and a hybrid office. The goal is to carry out the operationalization of professional burnout in the conditions of remote work and a hybrid office for the subsequent development of a software application for the prevention of professional burnout. The authors present a theoretical analysis of the problem under study based on the results of modern research. The risks of remote work are identified. The main markers of professional burnout are presented. Several groups of factors are considered, which determine the likelihood of an employee developing a syndrome of professional burnout: socio-demographic, personal, organizational and socio-psychological. To obtain information that a subordinate is prone to burnout, the authors suggest using special techniques. The author’s operationalization of professional burnout is presented. In the author’s operationalization, the authors tried to consider the structural components of professional burnout based on the symptoms, stage of development, and factors on which the likelihood of burnout development depends.
Corporate Culture of the University: the Role of the Trade Union
Authors: Ermolaeva S. , Mal'cev A.
Published: July 2023

One of the important functions of personnel management at present is the management of corporate culture. The culturological approach in management allows you to combine all forces (resources) to achieve the goals of the organization, solving its tasks. This approach allows us to take into account the uniqueness of  a  particular company, to  focus on  the integration of  all personnel in  achieving the goals of  the organization, the formation of  loyalty, competencies, solidarity. Among the functions of the trade union noted in the documents of the organization, the organizational function, the organization of cultural mass, sports events, traditional professional holidays are presented. The role of management in the development of corporate culture is undeniable, at the same time, bipartisanship at the local level, as well as tripartism at other levels of social partnership presupposes the participation of employees (their trade union representatives) in the development of labor and other relations, in the improvement of corporate culture in the organization. The formation of values and norms, certain stereotypes of behavior occurs within the framework of the concept of social partnership in the organization. The role of the trade union as an organization uniting employees, as a participant in social partnership is in demand. This role is noted in the conducted research through the participation of the trade union in supporting traditions in the organization, participating in negotiations, discussing a Collective agreement, supporting staff in difficult situations (providing material, informational and legal assistance to trade union members and all employees of the organization) and other areas. The trade union participates in the management of corporate culture, which includes not only the management of the internal environment of the organization, but also the management of the image of the organization, its business reputation.
EVALUATION OF THE PERSONNEL MOTIVATION SYSTEM OF A CONSTRUCTION ORGANIZATION IN THE CONTEXT OF THE THEORY OF GENERATIONS
Authors: Plutova M. , Popova O. , Lagutina E.
Published: July 2023

Modern conditions for the functioning of organizations require constant updating of approaches to personnel management, including new approaches are being formed in relation to the management of personnel motivation. Despite the unification of job duties by professional affiliation, each employee is individual and his needs, principles, beliefs are individual, and this should be considered when working with personnel. When forming a system of motivation and incentives, one should consider the specifics of each working generation in the organization. Theories of generations substantiate the important characterizing qualities of generations, their features, and the influence of historical and socio-economic factors during the formation of each generation separately. The authors, when assessing the existing system of motivation of the personnel of a construction organization, took the theory of generations as a criterion basis. Improving the system of motivation and incentives in the context of the theory of generations makes it possible for the organization to contribute to the growth of the efficiency of the work of personnel, reduce turnover and reduce the costs associated with training and adaptation of personnel. The results of the work can be used as the basis for improving the systems of motivation of the personnel of construction organizations. It is possible to use the results of the study in the development of motivation systems for business entities, departments for personnel management of enterprises and organizations.
BE FRIENDS OR NOT? REPRESENTATIONS OF EMPLOYEES OF RUSSIAN ORGANIZATIONS ABOUT THE ADMISSIBILITY OF INFORMAL RELATIONSHIPS AT WORK
Authors: Romanova I.
Published: July 2023

The article discusses various aspects of friendship among employees of the organization. The positive impact of friendship on colleagues is described, as well as the risks of close working relationships. Possible tools for managing friendship on the part of management are also considered. The results of a survey of employees of Russian companies on the topic of friendly relations between colleagues are presented. It was found that the majority of respondents have friends at work and, in general, have a positive attitude towards friendship among colleagues. The survey participants see the greatest benefit from friendship in improving the moral and psychological climate of the team, and the biggest adverse effect of friendship is, in their opinion, “distraction from work.”
IDENTIFICATION OF THE RELATIONSHIP OF INDIVIDUAL AND PERSONAL CHARACTERISTICS OF SALES MANAGERS WITH THE EFFECTIVENESS OF PROFESSIONAL ACTIVITY
Authors: Tokareva Y. , Polozov A. , Petuhova M. , Morohov N.
Published: July 2023

The article is devoted to the study of personal characteristics of sales managers and their impact on the level of professional success.

A successful sales manager is the one that company executives are “hunting” for. He is offered a job on the most favorable terms for him. Due to the fact that: effectively leads the client through the sales funnel — from the first touch to the closing of the transaction; sells with minimal discounts or without them at all; launches word of mouth and motivates the client to bring new customers; gets pleasure from work; and after each sale, it strives to get even more customers, profits and drive.

The article examines the criteria and individual personal characteristics of managers and their relationship with the effectiveness of professional activity in sales.

Using the MBTI personality type testing methods and the I.D. Weisband test, the analysis of the sales managers’ abilities to motivate customers to purchase, taking into account their type of character, as well as the manager’s ability to justify the benefits of the purchase for the client based on his profile activities, was carried out.

The authors studied and formed the requirements of employers for sales managers, selected the necessary materials and testing methods, and also formed a model for selecting a sales manager based on the personality structure. Based on the data obtained, the positive impact of using a typological model of the personality structure in solving tasks for the selection of sales managers was revealed.
Retroperitoneal hematoma: a sequela of acute hemorrhagic pancreatitis post endoscopic retrograde cholangiopancreatography
Authors: Navari Yasaman , Bagheri Amirbehzad , Chinnappan Justine , Khine Su , Marcus Huda , Bachuwa Ghassan
Published: July 2023

Endoscopic retrograde cholangiopancreatography (ERCP) is a diagnostic and therapeutic tool for pancreaticobiliary diseases. Like every other procedure, ERCP can lead to complications that include pancreatitis, cholecystitis, perforation, and rarely, retroperitoneal hematoma. We present a case of post-ERCP acute hemorrhagic pancreatitis resulting in retroperitoneal hematoma and sequelae of unilateral hydronephrosis and ileus. The patient was treated supportively and had good clinical improvement with resolution of hydronephrosis, ileus and more importantly tolerating oral diet without further episodes of abdominal pain.
Peer support after exposure to trauma: an evaluation
Authors: Romano Vincent
Published: July 2023

Background:

There are various staff wellbeing programmes used across the emergency services. The British Military recognised single-session models were not effective and developed Trauma Risk Management (TRiM). A number of organisations now use TRiM as a peer-led traumatic stress support system, including the North West Ambulance Service.

Aims:

This evaluation aimed to identify engagement with TRiM across the North West Ambulance Service.

Method:

A combination of quantitative and qualitative data was analysed from those who engaged with TRiM.

Findings:

There was a perception that road traffic collision (RTC) and cardiac arrests would cause acute stress symptoms and require a TRiM assessment; this was validated by the uptake of assessments and referral to professional counselling following such incidents.

Conclusion:

TRiM can provide effective peer-delivered support across a large geographical workforce. Implementation and coordination are key to ensuring success.
Team Works on New Hydrogen Storage Solution
Authors: Knight Helen
Published: July 2023

Porous materials could safely take in and release gas inside vehicles
Graphene Spikes could Kill Bacteria on Implants
Authors: Knight Helen
Published: July 2023

Vertical flakes may prevent infection and reduce the risk of rejection
Low-Boom Plane Project
Authors: Nathan Stuart
Published: July 2023

Supersonic aircraft set to go on trial in US
Paving the Electric Way
Authors: Wordsworth Saul
Published: July 2023

AS PART OF ITS GROWING PORTFOLIO OF EVS, VOLVO CE'S NEW DD25 ASPHALT COMPACTOR WILL MAKE ITS DEBUT AT CONEXPO – THE OEM'S FIRST ELECTRIC MACHINE FOR ROAD BUILDING
Focus on Innovation
Authors: Sampson Ben
Published: July 2023

Investment at MOD Boscombe Down is helping its engineers meet future test demands for defence and civil aviation
Problems and possibilities for Swedish working-class literature in a neoliberal age
Authors: Gustafson Magnus
Published: July 2023

In recent decades, inequality has increased in Sweden. The increasing gaps are connected with policies that are often called neoliberal. How does working-class literature relate to these social problems and what literary possibilities does it open up? In this article I discuss these questions based on some literary examples from Swedish contemporary working-class literature. These literary examples have attracted much attention. My perspective is that I see working-class literature as literature with a distinct use value and a literature that has specific functions in the working-class literature context (Felski, 2008).

Kristian Lundberg, Johan Jönson and Jenny Wrangborg all give personal accounts from workplaces. Such can be valuable. The problem with Lundberg and Jönson is that they tend to be introverted and egocentric. Especially Lundberg lacks the class perspective. Perhaps Lundberg’s Yarden (The Yard, 2009) should be described as confessional literature rather than working-class literature. With Susanna Alakoski the working-class is hidden behind the concept of poverty. The working-class as actor is absent. The labor movement as well. Instead, it is the middle class who appear as actor. Through the role of jester, Jönson makes class society visible. The role of jester could be seen as a specific rhetorical strategy and a literary device to create a distancing effect, or Verfremdungseffekt. Wrangborg connects to the legacy of early working-class literature with struggle poems. From within the workplace she describes work situations and experiences of class.

Emil Boss takes a close look at language and concepts in a postpolitical age when old concepts have changed meaning. It is a crucial task for working-class literature to explain, interpret and examine old concepts that have changed meaning in a new political era, when the labor movement has lost contact with previous ideals and social democratic governments pursue rightwing politics, thus making it difficult to distinguish between left and right.
Favipiravir: An Effective Rna Polymerase Modulating Anti-Influenza Drug
Authors: Yash Shertate , Sarika Kamble , Laxmikant Borse
Published: July 2023

ABSTRACT: Combination of all the aspects are covered in this review from anti-influenza drug.Several articles neglected to include a point of view. The majority of review papers emphasiseon epidemiology. In order to lessen the financial burden of disease and its negative effects, it is important to raise awareness about disease and how to manage it.The medicine favipiravir,additionally called T-705 (5-fluro-2-oxo-1H-pyrazine-3-carboxamide), by selection and powerfully inhibits the polymer-dependent polymer accelerator (RdRp) of polymer viruses. Favipiravir was discovred by the company Toyama Chemical Co., Ltd.By searching a chemical library for the respiratory illness virus's antiviral properties. Favipiravir-RTP (favipiravir ribofuranosyl-5′-triphosphate), the active version of the drug, is recognised by RdRpas a substrate and restrains the polymer accelerator's activityFavipiravir is efficient against a broad kind of subtypes and variations of respiratory disorder viruses.
Spatio-Temporal Change Detection Analysis of Land Use Land Cover of Bathinda District, Punjab, India
Authors: Ahmad Naseer
Published: July 2023

ABSTRACT: Due to rapid industrialization and urban sprawl in the last few decades, the land use pattern and its consumption takes place at a large scale that could lead to problems such as over-exploitation of land resources, food insecurity and pollution. It becomes imperative to carry out monitoring and subsequent modelling of land use land cover (LULC) changes. An attempt was made to study the changes in the LULC pattern of district of Bathinda, Punjab, India. Remote sensing (RS) and geographical information system (GIS) were used to perform the analysis of satellite data using image processing and classification procedures. For preparing LULC maps, supervised classification was carried out using maximum likelihood classification (MLC) algorithm, aided with Earth Resources Data Analysis System (ERDAS) Imagine 2014 and ArcGIS 10.3 software. Further, change detection study was done using multi-temporal Linear Imaging Self Scanning Sensor-III (LISS-III) data sets of the year 2006 and 2018 to analyze the temporal changes. It was observed that the region is occupied by various ground features such as water, built-up area, agricultural land, vegetation/trees and fallow land. The results revealed that the area under water bodies have increased by 0.413km2 in 2018. The built-up areas including human settlements, commercial infrastructures, roads and other pavements, have increased from 584.448km2 to 852.140km2 between 2006 and 2018, whereas the agricultural land has reduced from 2686.121km2 to 2398.384km2 during the period. The area under vegetation (trees) indicated that there was an increasing trend from 28.490km2 to 54.678km2 during 12years of time span whereas, the fallow land/barren land showed a decreasing trend from 26.361km2 to 18.367km2. It is suggested that the LULC change detection studies are very significant to conserve the land resources and to avoid further degradation.
Molecular Docking, Synthesis of Novel Schiff Base 1, 3-Thiazine Compounds from 3-Methoxy Chalcone and Evaluation of Their Anxiolytic Activity
Authors: S Sonu , Gautam Girendra Kumar , Mishra Arun Kumar , Parveen Baby Rabiya , Saini Rajat , singh Harpreet
Published: July 2023

As they represent a sizable class of naturally occurring and synthetic chemicals with potent biological activity in the pharmaceutical and biological fields, 1, 3 Thiazine heterocycles are of great interest. The goal of this project was to create the Schiff base. 3,-Methoxychalcone derivative of 1,3-thiazine. TLC, IR, 1HNMR, 13C NMR, each mass calculation were accustomed to identify the compositions of recently created targeted substances. Using an Elevated plus maze, the test compounds (B1–11) were examined for their ability to reduce anxiety. The most effective CNS medications were B1 and B8 compounds.
Thermal and Optical Properties of NiO nano doped in PVDF-HFP: Mg(ClO4)2 Nano Composite Solid Polymer Electrolytes
Authors: Mallikarjun A. , Kumar J. Siva
Published: July 2023

NiO doped nano composite solid polymer electrolytes (SPEs) composed of PVDF-HFP (poly (vinylidene Fluoride hexafluoropropylene)): Mg(ClO4)2 with different weight concentration of NiO nanofillers synthesized by solution cast technique. NiO incorporated nano composite polymer electrolytes are characterized by UV-Visible spectroscopy to find direct and indirect band gaps. The thermal stability and structural changes of the nano composite polymer electrolytes is studied by DSC and noticed that PSN12 sample having optimum change. The changes in band gap values maybe due to greater number of Ni and Mg atoms from NiO and Mg(ClO4)2 salt are coordinating by donating electrons to F atom of the PVDF-HFP polymer. From the optical absorption measurements, the found values direct and indirect band gap was low, and these values are 3.8252 eV and 1.6885 eV respectively for the polymer electrolyte sample PSN12 where weight ratio of NiO is12% nanofiller incorporated PVDF-HFP: Mg(ClO4)2 polymer electrolyte.
Characterization of the Bryophyllum pinnatum leaf's Active Component and It's Antidiarrheal Potential
Authors: Yadav Priyanka , Mishra Arun K , Singh Harpreet
Published: July 2023

Diarrhea is a symptom experienced by nearly everyone, generally considered an increase in the volume, fluidity, and/or frequency of stools. Chronic diarrhea may affect ~5% of people in industrialized countries, and acute or chronic infectious diarrhea remains an important cause of morbidity in developing countries. The Crassulaceae family of plants includes the Bryophyllum pinnatum (Lam.) Oken plant, which is well renowned for its therapeutic properties. The main aim of the research is to assess the antidiarrheal property using Mgso4 induced diarrheal model and isolate an active compound. Both EAE and EE exhibited consistent effects. The Percentage of Inhibition of T1 (EE 200 mg/kg), T2 (EE 400 mg/kg), T3 (EAE 200 mg/kg) and T4 (EAE 400mg/kg) groups was found 41.51%, 61.32%, 32.56% and 52.78% respectively with standard Loperamide drug (at 3 mg/kg dose, p.o.). T2 (EE 400mg/kg) showed better outcomes because of isolated flavonoid substance, 4, 5, 7-trihydroxy flavones as a yellow pigment from ethanol-DCM, with the aid of analysis using UV, IR, NMR and mass spectroscopy, the substance, was characterized and identified as 4, 5, 7-trihydroxy flavones, with the chemical formula C15H10O5 from EE extract of Bryophyllum pinnatum (Lam.) Oken plant leaves. Finally, it can be concluded that flavonoids are responsible for the antidiarrheal activity and this may be used to determine the precise function of herbal medicine in contemporary society.
A Distributed Publish–Subscribe Algorithm Based on Spatial Text Information Flow
Authors: Liu Yangtao , Yu Xiaofeng
Published: July 2023

With the rapid development of society and the popularity of smart devices, the volume of information sent and received is increasing day by day. It has become very difficult to accurately and efficiently match a large number of events with a large number of subscriptions, and the event and subscription matching speed can no longer meet demand. To speed up the matching speed of events and subscriptions, this paper uses similarity and correlation to optimize the clustering operation and increase the data transfer and data throughput of the category fusion strategy. Firstly, the clustering operation is performed on the subscription messages, and the category to which the events belong is found according to the clustering result. Subsequently, in the category, the subscriptions matching the events are found. An on-the-fly subscription publishing algorithm is proposed to coordinate spatial information and event attribute information to handle not only the matching operation of events and subscriptions on-the-fly but also to perform subscription updates and category updates on the distributed environment on-the-fly. It can also perform clustering operations and matching operations instantly without prior knowledge. We design a distributed system for the publish–subscribe algorithm and propose a load balancing strategy for this algorithm on the distributed system. Subsequently, we experimentally validate the proposed publish–subscribe algorithm in this paper by building our own cluster and using real data.