bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSESSMENT OF THE REGIONS ECONOMIC POTENTIAL AND THEIR OPPORTUNITIES
Authors:   Donetsk National Technical University, Khobta Valentyna , Tonkyj Dmytro ,   Donetsk National Technical University, Panchenko Natalija ,   Donetsk National Technical University
Published: April 2022

Based on the analysis of methods for quantitative assessment of the economic potential of regions in the context of available resources, the direction of this process is systematized in the following areas: economic-geographical, production, demographic, information and macromodels. The necessary characteristics of the economic potential of cities and settlements, including the territory, population, production, investments and loans have been formulated. They reveal the main components of existing opportunities, which make it possible to create a basis for an objective assessment of the potential for socio-economic improvement, its acceleration and increase in effectiveness. For a wide coverage of the directions of changes and reflecting their dynamics, it is proposed to take into account the influence of the time factor on the expected development results based on the financial and mathematical apparatus known in the investment theory, reflecting the change in the value of cash flows in different periods of operation. Based on the diversification of regional economies, including economic, technical, social, innovative, investment, scientific and technical and other areas of activity, attention is focused on a comprehensive analysis of all components when calculating the potential. The article formulates the sequence of process stages of assessing the communities’ resource potential. It is proposed to form initial information in the context of three blocks: resource, economic development, growth reserves. This allows you to structure data based on the main aspects of the availability and reproduction of resources, which will provide a rational choice of development strategy. A vision of the assessment system characteristics has been formed, which is obliged to encompass the main constituent elements, which will make it possible to establish the nature of development and the necessary requirements for it. To generalize the assessment, methods are classified that provide the final characteristics, capabilities and scope of their application. The system of indicators for assessing the efficiency of using the economic potential of the region is considered, which includes two main blocks, target and resource.
INVESTIGATION OF SOCIAL VULNERABILITY OF LVIV REGION POPULATION
Authors:   State Institution «Institute of Regional Research named after M. I. Dolishniy of the National Academy of Sciences of Ukraine», Bachynska Mariya
Published: April 2022

The article studies the number of vulnerable segments of population. It is determined that the highest number of people with disabilities was marked in 2020 – 213.8 thousand people, whereas the smallest – in 2010, i.e. 176.7 thousand people. Increase of the number of people with disabilities consequently causes growth of the number of them per 1000 people of population. In the studied period, an annual growth of the index by 22.9% was marked. The author supplies expected indices of the growth of the number of retired people in Lviv region, forecast of the index of growth of the number of people with disabilities by using a linear model for four future periods; expected indices of increase of the average monthly retirement benefits. The research also examines a change of the number of healthcare establishments in Lviv region in 2013-2020. It is determined that in 2013-2020, hospital accommodation reduced by 24.1%, medical outpatient-polyclinic establishments – by 12.2%, and medical and obstetric centres – by 34.2%. The author of the work studied dynamics of the residential fund of Lviv region in 2013-2020 and determined that the fastest rate of growth of the volume of residential fund was marked in urban territory (by 20.6%). To reduce the negative impact of the factors on the most socially vulnerable categories of population, the state should maximize its efforts to provide conditions for a higher labour payment; to organize an effective system of social and economic defense of employees; to strengthen the targeted social support and primarily support of the vulnerable groups of population; to provide interest-free loans for vulnerable segments of population; to maximum provide housing for orphans after achieving the adulthood age; to educate social responsibility. The goal of the article is to prove the necessity of the social infrastructure development to reduce the social vulnerability of the Carpathian area population. In the process of the article writing, the author used a set of general scientific and specific methods of research. The graphical method was used to make visual presentation and to shape expected indices of growth of the number of retires people in Lviv region, increase of the number of people with disabilities by using a linear model and indices of growth of the average size of monthly retirement benefits. To make theoretical consolidation and conclusions, the abstract and logical method was used.
THE PATH DEPENDENCE CONCEPT APPLICATION IN THE STUDY OF STRUCTURAL TRANSFORMATION OF THE UKRAINE NATIONAL INNOVATIVE SYSTEM
Authors:   Petro Mohyla Black Sea National University, Netudyhata Kostiantyn , Pohromskyi Victor ,   Petro Mohyla Black Sea National University
Published: April 2022

In recent years, the concept of path dependence has been increasingly used in economics as a tool to explain the transformation of institutions. The need to develop a quality NIS, regulation of its structural transformation recognizes the relevance of this study. The aim of the article is to study the process of structural transformation of Ukraine NIS on the basis of the concept of “path dependence”. The possibilities provided by the concept of “path dependence” in the study of structural transformation of the domestic national innovation system (NIS) are considered. It is noted that the dependence of previous development severely limits the ability to change development strategies, which are possible only at bifurcation points when systemic changes occur. An attempt is made to comprehend the problems of modern NIS through the prism of the 1990s. Explaining the current state of the system through the prism of the concept provided an opportunity to consider the nature of the negative phenomena inherent in today’s domestic innovation system (high share of public sector in financing R&D expenditures, weak links between business and higher education sectors, low innovation activity, low costs on R&D at the level of business entities, weak involvement in the global innovation competition of enterprises). Over the last 30 years, many new measures have been introduced, including support for universities, optimization of former branch research institutes, reform of the Academy of Sciences, creation of innovation infrastructure, creation of scientific funds. To stimulate links in the innovation system, a separate set of horizontal tools was created: technology platforms, innovation clusters, mobility promotion, project consortia between research institutes (universities) and companies, and more. However, the results of all these activities remain not impressive enough. The necessity to take into account the factors of historical succession when designing the development of the Ukrainian innovation system is proved. It is important to effectively use not only modern borrowed institutions, but also to modify the traditional institutions that have ensured the development of the country in previous periods, taking into account the challenges of the time.
INTERNATIONALIZATION OF THE CONSTRUCTION INDUSTRY OF UKRAINE: CURRENT STATE AND PROSPECTS
Authors:   Prydniprovska State Academy of Civil Engineering and Architecture, Chala Veronika , Kuchyn Illia ,   Prydniprovska State Academy of Civil Engineering and Architecture, Diatlova Nataliya ,   Prydniprovska State Academy of Civil Engineering and Architecture
Published: April 2022

The article examines the dynamics of internationalization of the construction industry of Ukraine over the past decade. The reasons for the poor representation of domestic companies in the world market are revealed, the priority directions of the European integration policy for the construction market are substantiated. The dynamics of capital investment due to foreign residents and other key indicators of internationalization of the construction industry, such as exports, imports, the amount of foreign direct investment in the construction industry and foreign trade turnover in construction are analyzed. The results of calculations of the author's index of internationalization of the construction industry are presented. It shows that despite steady growth until 2013 and falling after political events in Ukraine, the situation stabilized briefly in 2016, followed by a sharp decline that continues to this day due to a number of global events such as the semiconductor crisis and the COVID-19 pandemic. It is determined that in order to improve the situation in the industry, it is necessary to direct state policy to increase the qualitative and quantitative levels of export potential. Particular attention should be paid to the development of promising global niches in construction, starting with production technology, where you need to focus on sustainable construction, or using software, blockchain technology, the Internet of Things both on and off the construction site, as well as obvious future benefits of investing in drone and robotics technology to do more routine or hazardous work and protect workers from potential risks, and to make full use of high-tech construction technologies and attract foreign investment to re-equip and implement innovative solutions in construction companies. The key factors influencing foreign direct investment and exports in the construction industry are identified, the projection of results as key indicators on which the comprehensive indicator of internationalization of the construction industry depends, allowed to reasonably identify indicators that most affect the index.
THEORETICAL FUNDAMENTALS OF STRATEGIC MANAGEMENT OF HUMAN CAPITAL OF THE ENTERPRISE
Authors:   Dnipro National University named after Oles Honchar, Grynko Tatyana
Published: April 2022

The article is devoted to the study of theoretical approaches to the interpretation of the essence of the category of human capital and the definition of conceptual provisions of strategic management of human capital in enterprises in modern economic conditions. The article considers the main provisions of traditional, alternative, extended and other approaches to the interpretation of the term “human capital” by foreign scholars. Perspectives on the essence and content of human capital are presented by some Ukrainian scientists. The article is devoted to the study of theoretical approaches to the interpretation of the essence of the category of human capital and the definition of conceptual provisions of strategic management of human capital in enterprises in modern economic conditions. The article considers the main provisions of traditional, alternative, extended and other approaches to the interpretation of the term “human capital” by foreign scholars. Perspectives on the essence and content of human capital are presented by some Ukrainian scientists. The target orientation of the research of the substantive essence of the category “human capital” is determined, which is to assess the possibility of its development and the ability to manage it taking into account the external and internal environment of the enterprise. It is proved that human capital should be considered as a new effective resource, the use of which contributes to the socio-economic development of the enterprise and the state, investment in human capital provides long-term socio-economic multiplier effect for all market participants. It is determined that strategic human capital management is aimed at ensuring the efficiency of economic activity and sustainable development of the enterprise through the effective formation, development and use of human capital. It is noted that strategic human capital management should be considered in the context of strategic management of intellectual capital of the enterprise. The place and role of strategic analysis and evaluation of human capital quality in strategic human capital management of the enterprise are outlined. The specific features of strategic human capital management of the enterprise are considered, in particular, such as time length, orientation on the principle of balance of human capital flows, consideration of each employee of the enterprise as his strategic partner. It was concluded that strategic human capital management contributes to the added value of the enterprise, increase the level of corporate culture, and improve the image of the enterprise.
L'originarsi della metafora in Autopsicografia di Fernando Pessoa
Authors: Francato Leopoldo
Published: April 2022

In questo lavoro l'autore, dal vertice di studio di un'opera d'arte colta nei suoi aspetti stilistici e formali, approfondisce la conoscenza della poesia Autopsicografia di Fernando Pessoa. Il poeta portoghese è in grado di trascinare il lettore nei territori della psiche al limite del formularsi del pensiero, muovendosi attraverso il discorso eteronimico e la necessità della finzione. Si tratta di seguire il corso dei movimenti di pensiero interni alla poesia stessa, nell'articolazione dell'esperienza del poeta nell'incontro con il divenire del suo stesso componimento. Tale movimento porterà alla nascita di un'immagine metaforica, esito dell'attivazione della funzione trascendente secondo le teorizzazioni di Jung.   
МЕТОДИКА КОНСТРУЮВАННЯ ЗАВДАНЬ ОЦІНЮВАННЯ РЕЗУЛЬТАТІВ НАВЧАННЯ СТУДЕНТІВ ТЕХНІЧНИХ КОЛЕДЖІВ
Authors: Лузан Петро , Мося Ірина , Пащенко Тетяна , Ярош Любов
Published: April 2022

Актуальність визначається реформуванням змісту, методів, форм, технологій інженерно-технічної освіти, що відбувається на основі компетентнісного підходу й зумовлює потребу в таких діагностичних методиках, які б дозволили ефективно управляти особистісно орієнтованою педагогічною взаємодією, об’єктивно й надійно оцінювати рівень опанування майбутніми механіками, техніками, технологами компонентами освітньо-професійних програм.
Мета: розроблення методики конструювання й оцінювання складності індивідуальних навчальних завдань як поетапної процедури, заснованої на аналізі умови пропонованої навчальної дії та показників новизни її виконання студентом технічного коледжу.
Методологія дослідження базується на єдності діяльнісного, системного, особистісно-орієнтованого та технологічного підходів, що дало змогу розробити студентоцентровану, алгоритмізовану, орієнтовану на структуру навчальної дії методику конструювання індивідуальних завдань оцінювання освітніх досягнень студентів технічних коледжів.
Результати: на основі концепції поетапного формування розумових дій виокремлено показники опису навчальних дій у певній послідовності їх формування (форма подання виконавцю змістової частини орієнтовної основи дії – наявність в орієнтовній основі дії операцій щодо трансформації об'єкта – форма подання об’єкта дії – форма трансформації об’єкта дії – ступінь новизни для здобувача освіти дії, що виконується); наведено приклади конструювання системи індивідуальних навчальних завдань студентів.
Висновки: доведено необхідність формалізації процедури оцінювання складності індивідуальних навчальних завдань студентів шляхом використання показників орієнтовної основи дії, виконавчої частини та новизни дії задля їх диференціації від найпростіших до складних, високоінтелектуальних.
INVESTIGATION OF THE SOLID MINERAL DEPOSITS IN KANO STATE'S SCHIST BELT USING GEOCHEMICAL ANALYSIS
Authors: Shehu Jamaluddeen , Yelwa N. A.
Published: April 2022

This paper uses geochemical analysis to investigate solid mineral deposits in Kano state's schist belt. A number of geophysical studies have recently focused on the area, with one of them estimating the causative body parameters through modeling of ground magnetic data collected in the study area; a follow-up study like this is thus required. Using an Agilent Microwave Plasma-Atomic Emission Spectrometer (MP-AES), eight rock samples from the study area were prepared for geochemical analysis. The study area was discovered to be rich in iron, chromium, aluminum, silicon, calcium, potassium, zinc, and manganese, with mean values of 157.10, 6.35, 274.71, 324.76, 27.83, 239.79, 25.49, and 160.20 ppm, respectively. Muscovite, Fuchsite, Biotite, Chlorite, and Quartz are schist minerals rich in these elements. Gold and silver were also discovered, although in small quantities, with mean values of 0.15 and 0.03 ppm, respectively. It is recommended that government and other stakeholders in the solid mineral industry should explore the study area in order to exploit these resources. It is also recommended that a radiometric study be conducted in the area to determine the presence of thorium and uranium, as well as the area's safety from radioactive hazards due to the high amount of potassium recorded.
ANALISA PENGARUH IKLAN, CASHBACK DAN USER FRIENDLY TERHADAP IMPULSE BUYING KONSUMEN DOMPET ELEKTRONIK OVO DI SURAKARTA
Authors: Yanti Aris Indri , Adhiyani Oryza Rully
Published: April 2022

Abstrak: Meningkatnya penggunaan uang digital atau yang kerap disebut e-money dalam 5 tahun terakhir membuka kesempatan bagi perusahaan untuk memasarkan produknya lebih luas. Pertumbuhan sebesar 361% sampai maret 2018. Salah satu dompet elektronik yang pertumbuhannya meningkat adalah OVO di bawah naungan PT Visionet Internasional.  Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh faktor iklan, cashback serta kemudahan penggunaan (user friendly) dompet elektronik terhadap impulse buying konsumen dompet elektronik OVO di Surakarta. Bentuk analisa statistik yang digunakan adalah uji Validitas dan realibilitas, uji asumsi klasik serta  analisa regresi berganda meliputi uji T dan uji F. Populasi dalam penelitian ini konsumen pengguna aktif OVO dengan memperhatikan kelompok usia, yaitu usia kelahiran 1965 – 2010 yang berdomisili di 5 kecamatan di Surakarta. Jumlah sample yang diambil sebanyak 200 sample. Teknik pengambilan sampel menggunakan purposive sampling. Penelitian ini perusahaan dompet elektronik OVO dalam kegiatan marketingnya dapat memberikan penekanan pada 3 variabel yang terbukti berpengaruh terhadap impulse buying yaitu iklan, cashback, user friendly untuk melakukan penetrasi pasar. Di antara 3 variabel bebas tersebut, variable bebas user friendly merupakan variabel yang paling berpengaruh terhadap variabel terikat impulse buying
PENGARUH PRODUCT INVOLVEMENT DAN PRODUCT KNOWLEDGE TERHADAP KEPUTUSAN PEMBELIAN KONSUMEN HONDA MOBILIO
Authors: Ubaidi Ibnu Auf , Batu Reminta Lumban
Published: April 2022

Kebutuhan masyarakat terhadap kendaraan seperti motor dan mobil dijadikan sebagai alat moblitas masyarakat dalam berpindah dari suatu daerah ke daerah lainya. Honda mobilio menjadi salah satu mobil jenis low MPV yang sangat laris di pasar Indonesia, akan tetapi penjualan honda mobilio di Indonesia terus mengalami penurunan, dimana pada tahun 2019 penjualan honda mobilio hanya mencapai 16.886 unit dari 42.932 unit di tahun 2015. Pengetahuan produk merupakan petunjuk bagi konsumen untuk dipertimbangkan ketika mengevaluasi produk dan keterlibatan produk dapat mendorong konsumen dalam mengambil keputusan akhir yaitu keputusan pembelian kerena konsumen memiliki kesesuaian atau relevansi antara produk dan diri pribadi kosumen Penelitian ini bertujuan untuk menganalisis pengaruh Product Involvement dan Product Knowledge terhadap Keputusan Pembelian Konsumen. Lokasi penelitian dilakukan di kota Bekasi. Populasi dalam penelitian ini adalah anggota Honda Mobilio Community Indonesia Bekasi Raya. Ukuran sampel adalah 145 orang. Teknik pengumpulan data melalui kuesioner. Metode analisis yang dipergunakan adalah Model Persamaan Struktural dengan pengolahan data menggunakan program Lisrel 8.0. Hasil penelitian ini menujukan bahwa terdapat pengaruh secara signifikan antara Product Involvement terhadap keputusan pembelian konsumen dan terdapat pengaruh secara signifikan antara Product Knowledge terhadap Keputusan pembelian. Adanya hubungan antara Product Involvement terhadap keputusan pembelian konsumen melalui Product Knowledge, serta memiliki pengaruh secara simultan antara Product Involvement dan Product Knowledge terhadap keputusan pembelian konsumen
MEDIASI KEPUASAN PELANGGAN PADA KUALITAS PELAYANAN DAN CITRA MEREK TERHADAP LOYALITAS PELANGGAN
Authors: Suwarno Putri Prisma Pradana , Ariani Sri Setyo , Surjanti Jun
Published: April 2022

Tujuan dilakukan penelitian ini untuk menganalisa pengaruh kualitas dari pelayanan dan citra suatu merek terhadap loyalitas yang dimediasi oleh kepuasan pada pelayanan jasa di UPT. PSMB-LT Surabaya. Objek penelitian merupakan penyedia jasa pelayanan pengujian, kalibrasi dan sertifikasi produk di bawah naungan Dinas Perindustrian dan Perdagangan (Disperindag) Provinsi Jawa Timur yang setiap tugas fungsi dan kerja diatur dalam Undang-Undang dan Peraturan Daerah Provinsi Jawa Timur. Penelitian ini menggunakan pendekatan kuantitatif. Sampel penelitian sejumlah 53 orang yang merupakan pelanggan yang telah melakukan proses pelayanan di UPT. PSMB-LT Surabaya dari tahun 2017 s/d 2019. Penelitian ini menggunakan software IBM SPSS 25 dan AMOS 22. Penelitian ini menjabarkan adanya pengaruh yang positif antara Kualitas Pelayanan, Citra Merek, dan Kepuasan Pelanggan terhadap Loyalitas Pelanggan. Kualitas Pelayanan juga berpengaruh signifikan terhadap Kepuasan dan Loyalitas Pelanggan. Namun, Citra Merek hanya berpengaruh secara signifikan terhadap Kepuasan dan  tidak berpengaruh secara signifikan terhadap Loyalitas Pelanggan. Kepuasan Pelanggan memediasi hubungan antara Kualitas Pelayanan dan Citra Merek terhadap Loyalitas Pelanggan di UPT. PSMB-LT Surabaya.
FAKTOR YANG MEMPENGARUHI GREEN PURCHASE BEHAVIOR GENERASI MILENIAL DI INDONESIA
Authors: Sutikno Vania , Anandya Dudi
Published: April 2022

Dampak yang ditimbulkan oleh kerusakan lingkungan membuat generasi milenial menyadari pentingnya menjaga kelestarian lingkungan, misalnya beralih mengonsumsi produk yang lebih ramah lingkungan. Tujuan penelitian ini adalah mengetahui perilaku konsumen milenial di Indonesia terkait dengan attitude, subjective norm, perceived behavioral control, environmental concern, green purchase intention,willingness to pay premium, beserta pengaruhnya pada green purchase behavior. Responden pada penelitian ini berjumlah 141 orang, yang diambil dari generasi milenial di Indonesia yang pernah membeli produk ramah lingkungan dan terlibat aktif dalam kegiatan pelestarian lingkungan. Data yang didapatkan kemudian dianalisa menggunakan Structural Equation Modelling (SEM) dengan program SPSS 18.0 dan AMOS 22.0. Hasil penelitian menyatakan bahwa attitude, subjective norm, dan perceived behavioral control tidak berpengaruh positif dan tidak signifikan terhadap green purchase intention, perceived behavioral control tidak berpengaruh positif dan tidak signifikan terhadap green purchase behavior, green purchase intention berhubungan positif dan signifikan terhadap green purchase behavior, environmental concern berpengaruh positif terhadap attitude, subjective norm, perceived behavioral control, dan green purchase intention, serta tidak ada pengaruh moderasi dari willingness to pay premium terhadap hubungan antara green purchase intention dan green purchase behavior.
Evaluation of Climate Adaptive Building Skins in the Last Decade
Authors: Bekler Cansu , Ayçam İdil , Gökşen Fulya
Published: April 2022

Efficient use of energy and indoor comfort is accepted as the priority of modern architectural design trends, making it obligatory to design building shells in a specific form to provide adequate flexibility for energy flow and thermal comfort. Accordingly, climate-adaptive building shells (CABS) offer opportunities to significantly reduce energy use in buildings and lower CO2 emissions while serving as a promising alternative for sustainability. This study examines the development of climate-adaptive, high-performance and advanced facade systems through office buildings where energy consumption is higher than other constructions. The research method used in the study is data collection, process tracing, and content analysis from qualitative methods. The study consists of two stages. In the first stage of the study, climate-adaptive facade systems are investigated in detail; facade systems that will form the sub-headings of the CABS term have been determined and explained through the literature. The second stage of the study examines climate-compatible facade systems in energy-efficient design. It considers the factors affecting energy-efficient façade systems following the analysis of the prominent headings in the literature review.
Prática profissional de fisioterapeutas e a utilização da CIF-CJ em um hospital materno-infantil
Authors: Teixeira Renato da Costa , Cunha Katiane Costa , Nobre Thaís Amanda Monteiro , Andrade Fabiana do Socorro da Silva
Published: April 2022

A atuação do fisioterapeuta em neonatologia e pediatria é recente. A CIF-CJ é o instrumento da OMS que proporciona uma linguagem unificada e padronizada, especificamente em crianças e jovens. Este estudo teve o objetivo de descrever as técnicas de avaliação e tratamento mais utilizadas por fisioterapeutas de um serviço público materno-infantil e identificar o conhecimento destes sobre a CIF-CJ. Trata-se de um estudo transversal com abordagem quantitativa, tendo como amostra fisioterapeutas com atuação em neonatologia e pediatria de um hospital público na região Norte. Foi utilizado como instrumento de coleta de dados um questionário com duas perguntas abertas sobre as práticas de assistência fisioterapêutica em neonatologia e pediatria e um Checklist da CIF-CJ em que os participantes marcavam os domínios e categorias mais relevantes para informação de funcionalidade de neonatos e crianças. As práticas de assistência mais relatadas foram as de fisioterapia respiratória. O Checklist da CIF-CJ resultou em 56 categorias abrangendo somente domínios de função e estrutura. O estudo evidenciou que os participantes têm um perfil profissional baseado no modelo biomédico, sugerindo que deve ser feito um maior treinamento de pessoal para que possa ser atingido o modelo multidimensional.
The Results of Scientific Research of Agro-engineering Scientific Organizations on the Development of Digital Systems in Agriculture
Authors:   RAS, Lachuga Yu.f. , Izmaylov A.Yu. ,   VIM, Lobachevskiy YA.P. ,   VIM, Shogenov Yu.Kh. ,   RAS
Published: April 2022

The main scientific and technical achiev ements and research results for 2021 of scientific institutions of agro-engineering profile of the Ministry of Science and Higher Education of the Russian Federation, which are under the scientific and methodological guidance of the Department of Agricultural Sciences of the Russian Academy of Sciences (RAS) in the section of mechanization, electrification and automation in the field of development of new machine technologies, energy-packed agricultural machinery, mobile energy and robotic technical means, digital systems for the production of the main types of competitive agricultural products, the development of efficient energy supply systems using artificial intelligence, renewable energy and modern technical service in the agribusiness.
Analysis of the Quality of Work of Shredders-Spreaders of Straw of Grain Harvesters
Authors:   Kostanay branch of ", Astafiev V.L. ,   SPC Agroengineering", Murzabekov T.A. ,   A. Baitursynov Kostanay Regional University
Published: April 2022

An analysis of the designs of various technical means for combine harvesters for chopping and spreading plant residues is presented, their advantages and disadvantages are identified, and the compliance of the quality of the technological process with the requirements of regulatory documents for the process of soil mulching with straw is established
Justification of the Adjusted Clearance of the Stripping Comb Deburring Blade and the Intensity of the Impact on the Fiber Flax Stalk During Deburring at the Root
Authors:   Center for Bast Fiber Crops, Chernikov V.G. , Rostovtsev R.A. ,   Center for Bast Fiber Crops, Soloviov S.V. ,   Center for Bast Fiber Crops
Published: April 2022

A theoretical substantiation of the size of the installation clearance of the deburring blade for the tow of fiber flax on the root is given, and the intensity of the effect of the working body on the stems of the plant is theoretically substantiated.
Pengaruh Kepemimpinan dan Kompetensi Wrausaha Terhadap Keberlangsungan Usaha Perusahaan Perseorangan (Badan Hukum) Di Kabupaten Ogan Komering Ulu
Authors: Rahayu Sri - , Noviansyah Noviansyah
Published: April 2022

The objectives of this study are: (1) to analyze and find out how the influence of leadership on the sustainability of legal entity individual business in Ogan Komering Ulu district ,and (2) to analyze and find out how the influence of entrepreneurial competence on sustainability of legal entity individual business in Ogan Komering Ulu district. The independent variables used are leadership and entrepreneurial competence, while the dependent variable is business continuity. The sample used in this study were One hundred and twelve respondents who were selected using the purposive sampling method; namely individual business with legal status in Ogan Komering Ulu Regency. The data were collected by questionnaires and documentation. The data were analyzed by using Linear Regression. The result of the analysis showed that R square (R2) was 61,2% and significance level was 0.05. This result showed that leadership and entrepreneurial competence had a positive influence on the sustainability of a legal entity individual business in Ogan Komering Ulu Regency.

Keywords : Leadership, Entrepreneurial Competence, Business Sustainability. Abstrak

Tujuan penelitian ini adalah : (1) untuk menganalisis dan mengetahui bagaimana pengaruh kepemimpinan terhadap keberlangsungan usaha perseorangan berbadan hukum di kabupaten Ogan Komering Ulu dan (2) untuk menganalisis dan mengetahui bagaimana pengaruh kompetensi wira usaha terhadap keberlangsungan usaha perseorangan berbadan hukum di kabupaten Ogan Komering Ulu. Variabel independen yang digunakan adalah kepemimpinan dan kompetensi wirausaha, sedangkan variabel dependen adalah keberlangsungan usaha. Sampel yang diteliti dalam penelitian ini sebanyak 112 responden yang dipilih menggunakan metode purposive sampling yaitu usaha perseorangan berbadan hukum di Kabupaten Ogan Komering Ulu. Data dikumpulkan menggunakan quisioner dan dokumentasi. Data dianalisis menggunakan Regresi Linear. Hasil analisis menunjukkan nilai R2 sebesar 61,2% dan tingkat signifikan sebesar 0,05. Hasil penelitian menunjukkan bahwa kepemimpinan dan kompetensi wirausaha memberikan pengaruh positif terhadap keberlangsungan usaha perseorangan berbadan hukum di Kabupaten Ogan Komering Ulu.

Kata Kunci: Kepemimpinan, Kompetensi Wirausaha, Keberlangsungan Usaha.
“Citizen Martyrs”: The Afghan Fatemiyoun Brigade in Iran
Authors: Schwartz Kevin L.
Published: April 2022

While much is made of the military capacity of the all-Afghan Fatemiyoun Brigade as an Iranian militia and proxy force in Syria, less attention has been devoted to how its fighters and their experiences have been integrated into Iranian society following deployment. As Afghans of the Fatemiyoun Brigade return to Iran – either as veterans or as bodies of martyrs – they have been incorporated into existing national frameworks of Shiʿi identity and martyrdom. Through the analysis of media reports, funeral processions, and visual iconography, this article demonstrates how state and non-state actors in Iran have used the example of Afghan “shrine defenders” as an occasion to re-invigorate the central importance of state narratives around Shiʿism and national sacrifice. Such practices have elicited new perceptions across government and media of Afghan contributions to the history of the Islamic Republic and have been accompanied by new mobilities and modalities for Afghans in Iranian society. While the experiences of Fatemiyoun fighters are not monolithic, and the reasons for enlisting varied, Afghans affiliated with the brigade are increasingly taking on citizenship characteristics, despite their non-citizenship status. In addition to fighting on behalf of the nation and Shiʿa community, Afghan members and veterans of the Fatemiyoun engage in civic acts of solidarity. Families of fallen fighters receive the financial benefits and cultural status accorded to “martyrs families.” Accordingly, the experience of the Fatemiyoun Brigade and its increased visibility in Iranian society raise questions about the future citizenship prospects of Afghans in Iran as well as notions of citizenship in the Islamic Republic more generally.
Rights Regimes and Interstate Migration Decisions
Authors: Nelson Michael , Witko Christopher
Published: April 2022

In their “laboratories of democracy,” state legislators, governors, and judges use their control over policy to experiment with citizens’ fundamental rights. Advocates argue that federalism preserves liberty by creating an easy exit option for citizens: faced with restrictive rights regimes, people can move to a state with more generous rights protections. There are reasons to doubt this account: groups most sensitive to rights restrictions be unble to move, people prioritize amenities like weather and economic circumstances, and people may be more sensitive to economic policy than rights policies. We use a conjoint experiment asking people to evaluate hypothetical job opportunities. We find that, restricting rights is generally repellant to would-be interstate migrants. This is especially so for Democrats and for those actively looking for jobs. Economic policies cannot make up for these restrictions.
SOCIAL ACTOR DOMINATION IN TAGAR.ID’S MINANGKABAU LANGUAGE GOSPEL APPLICATION NEWS
Authors: Firdaus Saiyidinal
Published: April 2022

This study aims to describe the dominance of social actor contained in the Tagar. Id's Minangkabau language Gospel application news. The researcher uses van Dijk's view in showing the relationship between social cognition and social actor in mass media's news. The researcher also uses Fairclough's socio-cultural approach in offering the relationship of discourse observed and socio-cultural perspective in the report. Thus, the researcher applies a qualitative approach with van Dijk's socio-cognitive and Fairclough's socio-cultural approach as an analytical knife. The study result indicates the person scheme and event scheme domination in the Tagar. Id's Minangkabau language Gospel application news. The two schemes play an essential role in describing Irwan Prayitno's figure as West Sumatera Governor through the Minangkabau socio-cultural reality. In van Dijk's point of view, social cognition is a form of effort in examining an event or events based on the characters' involvement in the news text. The figure of Irwan Prayitno as the governor of West Sumatra becomes a particular interpretation process for Tagar. Id journalist in producing news by analyzing the leadership form of Irwan Prayitno and the event that happened in Minangkabau community as details of Irwan Prayitno's profile, the socio-cultural reality of the Minangkabau community, and the reasons for rejecting the Minangkabau language Gospel application.
An Epidemiological Compartmental Model With Automated Parameter Estimation and Forecasting of the Spread of COVID-19 With Analysis of Data From Germany and Brazil
Authors: Batista Adriano A. , da Silva Severino Horácio
Published: April 2022

In this work, we adapt the epidemiological SIR model to study the evolution of the dissemination of COVID-19 in Germany and Brazil (nationally, in the State of Paraíba, and in the City of Campina Grande). We prove the well posedness and the continuous dependence of the model dynamics on its parameters. We also propose a simple probabilistic method for the evolution of the active cases that is instrumental for the automatic estimation of parameters of the epidemiological model. We obtained statistical estimates of the active cases based on the probabilistic method and on the confirmed cases data. From this estimated time series, we obtained a time-dependent contagion rate, which reflects a lower or higher adherence to social distancing by the involved populations. By also analyzing the data on daily deaths, we obtained the daily lethality and recovery rates. We then integrate the equations of motion of the model using these time-dependent parameters. We validate our epidemiological model by fitting the official data of confirmed, recovered, death, and active cases due to the pandemic with the theoretical predictions. We obtained very good fits of the data with this method. The automated procedure developed here could be used for basically any population with a minimum of adaptation. Finally, we also propose and validate a forecasting method based on Markov chains for the evolution of the epidemiological data for up to 2 weeks.
Salmonella Prevalence Varies Over Time and Space in Three Large, Adjacent Cattle Operations in the Southwestern United States
Authors: Hanson Devin L. , Loneragan Guy H. , Brown Tyson R. , Edrington Tom S.
Published: April 2022

We set out to describe the prevalence of Salmonella enterica in three large, adjacent cattle operations in the southern High Plains of the United States. Operations included two dairies (one of which routinely administers a commercially available Salmonella vaccine) and one feedlot. Samples were collected monthly for 12 months. At each sample collection, 25 freshly voided fecal pats and a sample from each of the water troughs were collected from each of five pens of cattle within an operation. Each monthly collection included a total of 375 fecal and ~32 water samples for a yearly total of 4,500 and 379 samples, respectively (note that the number of water troughs per pen varied within an operation). Salmonella was commonly recovered from fecal (71.3%) and water (28.5%) samples and tended to follow somewhat similar temporal patterns over time. However, its prevalence varied among operations despite being adjacent properties in that Salmonella was recovered from 61.3, 80.1, and 75% of fecal samples from dairy 1, dairy 2 and the feedlot, respectively. Salmonella prevalence in water samples across collection times averaged 36.1, 70.2, and 46.1% for dairy 1, dairy 2, and the feedlot, respectively. While it is uncertain why the Salmonella prevalence varied from operation to operation, the higher observed prevalence of Salmonella in water on dairy 2 and/or the use of a commercial Salmonella vaccine by dairy 1 may offer a partial explanation.
Fucoidan-Mediated Anisotropic Calcium Carbonate Nanorods of pH-Responsive Drug Release for Antitumor Therapy
Authors: Wang Pei , Tong Fei , Luo Jun , Li Zhihua , Wei Junchao , Liu Yuangang
Published: April 2022

The shape of nanoparticles can determine their physical properties and then greatly impact the physiological reactions on cells or tissues during treatment. Traditionally spherical nanoparticles are more widely applied in biomedicine but are not necessarily the best. The superiority of anisotropic nanoparticles has been realized in recent years. The synthesis of the distinct-shaped metal/metal oxide nanoparticles is easily controlled. However, their biotoxicity is still up for debate. Hence, we designed CaCO3 nanorods for drug delivery prepared at mild condition by polysaccharide-regulated biomineralization in the presence of fucoidan with sulfate groups. The CaCO3 nanorods with a pH sensitivity–loaded antitumor drug mitoxantrone hydrochloride (MTO) showed excellent antitumor efficacy for the HeLa cells and MCF-7 cells in vitro. We believe that anisotropic nanoparticles will bring forth an emblematic shift in nanotechnology for application in biomedicine.
Determine Corneal Biomechanical Parameters by Finite Element Simulation and Parametric Analysis Based on ORA Measurements
Authors: Qin Xiao , Tian Lei , Zhang Hui , Zhang Di , Jie Ying , Zhang Hai-Xia , Li Lin
Published: April 2022

Purpose: The Ocular Response Analyzer (ORA) is one of the most commonly used devices to measure corneal biomechanics in vivo. Until now, the relationship between the output parameters and corneal typical biomechanical parameters was not clear. Hence, we defined the output parameters of ORA as ORA output parameters. This study aims to propose a method to determine corneal biomechanical parameters based on ORA measurements by finite element simulation and parametric analysis.

Methods: Finite element analysis was used to simulate the mechanics process of ORA measurements with different intraocular pressure (IOP), corneal geometrical parameters and corneal biomechanical parameters. A simplified geometrical optics model was built to simulate the optical process of the measurements to extract ORA output parameters. After that, 70% of the simulated data was used to establish the quantitative relationship between corneal biomechanical parameters and ORA output parameters by parametric analysis and 30% of the simulated data was used to validate the established model. Besides, ten normal subjects were included to evaluate the normal range of corneal biomechanical parameters calculated from ORA.

Results: The quantitative relationship between corneal biomechanical parameters and ORA output parameters is established by combining parametric analysis with finite element simulation. The elastic modulus (E) and relaxation limit (G∞) of the ten normal subjects were 0.65 ± 0.07 MPa and 0.26 ± 0.15, respectively.

Conclusions: A method was proposed to determine corneal biomechanical parameters based on the results of ORA measurements. The magnitude of the corneal biomechanical parameters calculated according to our method was reasonable.
Exosomes Derived From CTF1-Modified Bone Marrow Stem Cells Promote Endometrial Regeneration and Restore Fertility
Authors: Zhu Qianqian , Tang Shengluan , Zhu Yanwen , Chen Di , Huang Jialyu , Lin Jiaying
Published: April 2022

Background: Thin endometrial tissue is a leading cause of embryo transfer failure, potentially contributing to sustained infertility and associated adverse outcomes. The application of exosomes derived from autologous or allogeneic bone marrow-derived stem cells (BMSCs) has been used to promote uterine repair following injury, and there is also prior evidence that stem cell transplantation can bolster fertility. Genetic modifications represent a primary approach to enhancing exosomal therapy strategies. The present study thus explored the effects of Cardiotrophin-1 (CTF1)-modified BMSCs-exo on fertility-related outcomes.

Methods: An adenoviral vector was used to generate CTF1-overexpressing BMSCs (C-BMSCs), after which exosomes were isolated from control BMSCs (BMSC-exos) and C-BMSCs (C-BMSC-exos). The angiogenic effects of C-BMSC-exo treatment were assessed through analyses of endothelial cell proliferation and tube formation. Model rats exhibiting endometrial thinning were administered C-BMSCs-exo, after which the effects of such treatment were assessed through H&E staining, Masson’s trichrome staining, and immunofluorescence analyses. The mechanistic basis for the proangiogenic effects of CTF1 as a driver of endometrial regeneration was additionally explored.

Results: C-BMSC-exo treatment of HUVECs was associated with enhanced neovascularization, as evidenced by improved in vitro proliferation, migration, and tube formation. Importantly, such treatment was also linked to tissue regeneration, neovascularization, and the suppression of localized tissue fibrosis in vivo. Regenerated endometrial tissue exhibited higher embryo receptivity and was associated with higher birth rates in treated rats. The upregulation of the JAK/PI3K/mTOR/STAT3 signaling pathways in C-BMSC-exo-treated rats may underscore the mechanistic basis whereby CTF1 can positively impact endometrial angiogenesis and regeneration.

Conclusion: Our data suggest that exosomes produced by CTF1-modified BMSCs can more effectively promote the regeneration of endometrial and myometrial tissues, driving neovascularization in a manner that improves endometrial receptivity in a rat model system, highlighting the therapeutic promise of this approach for patients diagnosed with endometrial thinning.
Extracellular Vesicles and Transforming Growth Factor β Signaling in Cancer
Authors: Rodrigues-Junior Dorival Mendes , Tsirigoti Chrysoula , Lim Sai Kiang , Heldin Carl-Henrik , Moustakas Aristidis
Published: April 2022

Complexity in mechanisms that drive cancer development and progression is exemplified by the transforming growth factor β (TGF-β) signaling pathway, which suppresses early-stage hyperplasia, yet assists aggressive tumors to achieve metastasis. Of note, several molecules, including mRNAs, non-coding RNAs, and proteins known to be associated with the TGF-β pathway have been reported as constituents in the cargo of extracellular vesicles (EVs). EVs are secreted vesicles delimited by a lipid bilayer and play critical functions in intercellular communication, including regulation of the tumor microenvironment and cancer development. Thus, this review aims at summarizing the impact of EVs on TGF-β signaling by focusing on mechanisms by which EV cargo can influence tumorigenesis, metastatic spread, immune evasion and response to anti-cancer treatment. Moreover, we emphasize the potential of TGF-β-related molecules present in circulating EVs as useful biomarkers of prognosis, diagnosis, and prediction of response to treatment in cancer patients.
From Vial to Vein: Crucial Gaps in Mesenchymal Stromal Cell Clinical Trial Reporting
Authors: Wiese Danielle M. , Wood Catherine A. , Braid Lorena R.
Published: April 2022

Retrospective analysis of clinical trial outcomes is a vital exercise to facilitate efficient translation of cellular therapies. These analyses are particularly important for mesenchymal stem/stromal cell (MSC) products. The exquisite responsiveness of MSCs, which makes them attractive candidates for immunotherapies, is a double-edged sword; MSC clinical trials result in inconsistent outcomes that may correlate with underlying patient biology or procedural differences at trial sites. Here we review 45 North American MSC clinical trial results published between 2015 and 2021 to assess whether these reports provide sufficient information for retrospective analysis. Trial reports routinely specify the MSC tissue source, autologous or allogeneic origin and administration route. However, most methodological aspects related to cell preparation and handling immediately prior to administration are under-reported. Clinical trial reports inconsistently provide information about cryopreservation media composition, delivery vehicle, post-thaw time and storage until administration, duration of infusion, and pre-administration viability or potency assessments. In addition, there appears to be significant variability in how cell products are formulated, handled or assessed between trials. The apparent gaps in reporting, combined with high process variability, are not sufficient for retrospective analyses that could potentially identify optimal cell preparation and handling protocols that correlate with successful intra- and inter-trial outcomes. The substantial preclinical data demonstrating that cell handling affects MSC potency highlights the need for more comprehensive clinical trial reporting of MSC conditions from expansion through delivery to support development of globally standardized protocols to efficiently advance MSCs as commercial products.