bluuebunny/crossref_metadata_2025 huggingface dataset:
Bacteriolytic activity of ruminal protozoa is affected by rate and type of common essential oils: Effect of thyme oil
Authors: Sahan Z.
Published: February 2024

Over the past two decades, research into the effects of essential oils (EOs) on rumen microorganisms as an alternative to antibiotics has  intensified. Yet, there are few investigations on rumen protozoa. To evaluate if EOs have antiprotozoal efficacy against rumen protozoa,  the present investigation was conducted. Using the potentiality of rumen protozoa to digest 14C-labeled bacteria, the influence of EOs on  in vitro protozoal activity was determined. For the study, orange peel, cinnamon, laurel, oleaster, garlic, and thyme essential oils were  selected. Control (without essential oil), 500 mg/kg, 1000 mg/kg, and 5000 mg/kg dosages were used. Except for garlic oil, all essential  oils showed a notable effect on antiprotozoal activity. The highest antiprotozoal impact was reported at 500 mg/kg and 1000 mg/kg  doses of thyme oil, with respective reductions of 89.1% and 84.8% in bacteria degraded by protozoa. Cinnamon and oleaster oils had the  strongest antiprotozoal efficacy at a concentration of 5000 mg/kg. At 5000 mg/kg doses of oleaster and cinnamon oils, the quantity of  14C-labeled bacteria degraded by protozoa was reduced by 96% compared to the group that served as the control. In conclusion, orange  peel, cinnamon, laurel, oleaster, and thyme oils demonstrated remarkable in vitro antiprotozoal activity; however, more comprehensive  research is required to analyse the effects of the EOs used in this study on rumen living groups such as protozoa, bacteria, and yeast and  on rumen dynamics.
Conjectures analogous to the Collatz conjecture
Authors: Briscese Fabio , Calogero Francesco
Published: February 2024

In this paper we introduce some conjectures analogous to the well-known Collatz conjecture.
On k-wave solutions of quasilinear systems of partial differential equations
Authors: Grundland Alfred Michel
Published: February 2024

In this paper, we establish a relation between two seemingly unrelated
concepts for solving first-order hyperbolic quasilinear systems of partial
differential equations in many dimensions. These concepts are based on a
variant of the conditional symmetry method and on the generalized method of
characteristics. We present the outline of recent results on multiple Riemann
wave solutions of these systems. An auxiliary result concerning a modification
of the Frobenius theorem for integration is used. We apply this result in order
to show that the conditional symmetry method can deliver larger classes of
multiple Riemann wave solutions, through a simpler procedure, than the one
obtained from the generalized method of characteristics. We demonstrate that
solutions can be interpreted physically as a superposition of k single waves.
These theoretical considerations are illustrated by examples of
hydrodynamic-type systems in (n+1) dimensions.
Hamiltonian and recursion operators for a discrete analogue of the Kaup-Kupershmidt equation
Authors: Peroni Edoardo , Wang Jing Ping
Published: February 2024

In this paper we study the algebraic properties of a new integrable
differential-difference equation. This equation can be seen as a deformation of
the modified Narita-Itoh-Bogoyavlensky equation and has the Kaup-Kupershmidt
equation in its continuous limit. Using its Lax representation we explicitly
construct a recursion operator for this equation and prove that it is a
Nijenhuis operator. Moreover, we present the bi-Hamiltonian structures for this
new equation.
Degree growth of lattice equations defined on a 3x3 stencil
Authors: Hietarinta Jarmo
Published: February 2024

We study complexity in terms of degree growth of one-component lattice
equations defined on a $3\times 3$ stencil. The equations include two in Hirota
bilinear form and the Boussinesq equations of regular, modified and Schwarzian
type. Initial values are given on a staircase or on a corner configuration and
depend linearly or rationally on a special variable, for example
$f_{n,m}=\alpha_{n,m}z+\beta_{n,m}$, in which case we count the degree in $z$
of the iterates. Known integrable cases have linear growth if only one initial
values contains $z$, and quadratic growth if all initial values contain $z$.
Even a small deformation of an integrable equation changes the degree growth
from polynomial to exponential, because the deformation will change
factorization properties and thereby prevent cancellations.
An exercise in experimental mathematics: calculation of the algebraic entropy of a map
Authors: Viallet C. M.
Published: February 2024

We illustrate the use of the notion of derived recurrences introduced earlier
to evaluate the algebraic entropy of self-maps of projective spaces. We in
particular give an example, where a complete proof is still awaited, but where
different approaches are in such perfect agreement that we can trust we get to
an exact result. This is an instructive example of experimental mathematics.
On the Lagrangian multiform structure of the extended lattice Boussinesq system
Authors: Nijhoff F. W. , Zhang D. J.
Published: February 2024

The lattice Boussinesq (lBSQ) equation is a member of the lattice
Gel'fand-Dikii (lGD) hierarchy, introduced in \cite{NijPapCapQui1992}, which is
an infinite family of integrable systems of partial difference equations
labelled by an integer $N$, where $N=2$ represents the lattice Korteweg-de
Vries (KdV) system, and $N=3$ the Boussinesq system. In \cite{Hiet2011} it was
shown that, written as three-component system, the lBSQ system allows for extra
parameters which essentially amounts to building the lattice KdV inside the
lBSQ. In this paper we show that, on the level of the Lagrangian structure,
this boils down to a linear combination of Lagrangians from the members of the
lGD hierarchy as was established in \cite{LobbNijGD2010}. The corresponding
Lagrangian multiform structure is shown to exhibit a `double zero' structure.
A Fake Profile Detection Model Using Multistage Stacked Ensemble Classification
Authors: Swetha Chikkasabbenahalli Venkatesh  , Sibi Shaji  , Balasubramanian Meenakshi Sundaram
Published: February 2024

Fake profile identification on social media platforms is essential for preserving a reliable online community. Previous studies have primarily used conventional classifiers for fake account identification on social networking sites, neglecting feature selection and class balancing to enhance performance. This study introduces a novel multistage stacked ensemble classification model to enhance fake profile detection accuracy, especially in imbalanced datasets. The model comprises three phases: feature selection, base learning, and meta-learning for classification. The novelty of the work lies in utilizing chi-squared feature-class association-based feature selection, combining stacked ensemble and cost-sensitive learning. The research findings indicate that the proposed model significantly enhances fake profile detection efficiency. Employing cost-sensitive learning enhances accuracy on the Facebook, Instagram, and Twitter spam datasets with 95%, 98.20%, and 81% precision, outperforming conventional and advanced classifiers. It is demonstrated that the proposed model has the potential to enhance the security and reliability of online social networks, compared with existing models.
Parental Stress Scale Validation
Authors: Desiningrum Dinie Ratri , Hermawati Donna , Somantri Maman , Indriana Yeniar , Rusydana Alhimna
Published: February 2024

Children with special needs require specialized therapy due to developmental problems or anomalies. To carry out treatment, attend suitable schooling, medicine, and even for daily activities, special needs children may require full or partial support from a caregiver. The high burden of caregivers with special needs generates a terrible quality of life, which impacts mental health and can even lead to unfavorable parental attitudes toward children with special needs. This study aims to validate the Parental Stress Scale (PSS) developed by Deater-Deckard. The Indonesian translation technique refers to the guidelines provided by the International Test Commission. The sample data comprises 250 individuals, including both mothers and caregivers. The results indicate a good fit of the second-order confirmatory factor analysis (CFA) measurement model with the PSS. The reliability of the three PSS dimensions is robust, as evidenced by Composite Reliability (CR) and Average Variance Extracted (AVE) values for parent distress (0.895; 0.552), difficult child (0.907; 0.594), and parent-child dysfunctional relationship (0.954; 0.749). Moreover, the PSS demonstrates both convergent and discriminant validity. Hence, the translation findings affirm the legitimacy and reliability of the Parental Stress Scale (PSS) for use in the Indonesian context.
Ayurvedic Management of Pancreatitis
Authors: Snehal Patel  , N. Sridhar
Published: February 2024

Pancreatitis is the life threatening metabolic pathology of the gastrointestinal system. It progressively damages the pancreas and result in the loss of its functions. The prevalence rate of pancreatitis in India is 7.9 per 10, 0000. For male and female respectively 8.6 and 8 in India. With overall 10 year and 20 year survival rates are estimated to be about 70% to 45% respectively. In the contemporary science the treatment protocol is limited to painkillers, intravenous fluids and pancreatic enzymes. Despite of advance techniques in the allopathic science the prognosis of the disease is unclear. Ayurvedic formulations of mineral complex including a diet and moderate rest have shown excellent result. In this case report a 40 year old male patient a known case of chronic pancreatitis with recurrent abdominal pain which radiates to back, nausea, vomiting, tenderness, anorexia, along with elevated serum amylase level was managed effectively with Ayurvedic medications by the Department of PG Study in Shalyatantra OPD Dr. BRKR Government Ayurvedic Medical College and Hospital, Hyderabad. In Ayurveda this condition can be correlated Agnashayashoth which comes under Pittodara. And it was successfully treated with the medications like Shankha vati, Kravyadi ras, Arogyavardgani vati. Within 4 months of treatment patient become normal. There was no pain abdomen, nausea, vomiting, bloating of abdomen. And serum amylase came to its normal level. This shows that Ayurvedic herbo mineral formulations showing promising result in the management of pancreatitis.
Molecular Mechanisms Associated with Neurodegeneration in Alzheimer's disease
Authors:   Universidad Michoacana de San Nicolás de Hidalgo, Rodríguez Rubén Rangel , Estrada Luis Enrique Ruiz ,   Universidad Autónoma de Guadalajara, Mendoza Frida Michelle Salazar ,   Universidad de Guadalajara, Hernandez Christian Aaron Torres ,   Universidad Autonoma De Durango, Campus Laguna, Garcia Matt Partida ,   Universidad de Guadalajara
Published: February 2024

Alzheimer's disease (AD) is a progressive and irreversible pathology in which there is a continuous neurodegeneration process, clinically characterized by decreased cognition, memory and behavior alterations. Currently, the mechanisms behind AD progression are more clear, redefining it as a multifactorial disease on which aging, genetics,metabolism and environment play an important role on the onset. The complex molecular mechanisms interplay and generate a state of inflammation.Thus, creating neurodegeneration. Objectives: This review focuses on recopilating and describing the molecular mechanism behind neurodegeneration in AD. Furthermore, the relation between risk factors and the mechanism will be encompassed. Methods: A bibliographical review was carried out. Databases such as Pubmed, MDPI,sciencedirect, Termidia publishing house, scielo and the National institute of aging were used. Articles in English and Spanish between 2004 and 2023 were included. The keywords used were:Alzheimer's disease, neurodegeneration, beta-amyloid, tau protein, neuroinflammation, cognitive disorder, tangles, biomarkers. Results and discussion: Millions of people are exposed to multiple risk factors for AD. In every one of them, there are molecular mechanisms involved, which will eventually lead to AD´s main pathological changes, Beta amyloid deposition and tau pathology, causing neurodegeneration. Conclusions: Alzheimer's disease is an international public health problem that is affecting the lives of millions of people.To address this, we have to fully understand the molecular base of its development, in order to approach new treatments.
Cloud-Driven Transformation: Ensuring Security and Privacy in Data and Application Modernization
Authors:   Senior Data Consultant, MD, USA, Devineni Siva Karthik , Olivers Brownmagnus ,   Senior Database Specialist, MD, USA, Mullapudi Mahidhar ,   Senior Software Engineer, Microsoft, WA, USA
Published: February 2024

Today, businesses are advancing their IT strategies to leverage cloud environments providing greater scalability and efficiency in the changing digital environment. This indicates that it will be the modernization of data and apps that will lead the way as enterprises try to adapt themselves to the change brought about by the cloud. Even though they are not intentionally constructing a new entry medium that may be readily stolen, information providers in both the public and commercial sectors are also facing critical challenges regarding data security. At the same time as it satisfies the requirements of commercial customers as well as those of public sector organizations, this article provides the many methods that may be used to build cloud computing systems that protect the data of customers, guaranteeing that it is kept private. Also included in this are the methods for safely transferring client information from servers housed in your office building to the cloud, as well as the best practices that are prevalent within a certain industry and particulars that are applicable exclusively to a particular sort of company activity
CT Head Lens Exclusion Audit
Authors:   New Cross Hospital, Wolverhampton, UK, Kurian Merina , Pang Weehaan ,   Consultant Radiologist, UK, Bapusamy Arivalagan ,   Consultant Radiologist, UK
Published: February 2024

Objective: An audit was conducted to assess the number of CT head scans in which one or both lenses of the eye were excluded, from scans conducted in the A&E and inpatient setting, as well as in the outpatient setting in a UK district general hospital. For the purposes of this paper, we will focus on the inclusion of both lenses in the A&E and inpatient setting, as well as the outpatient setting in both audit loops. Study Design: The data was collected via an audit cycle. The first audit loop reviewed lens exclusion in 50 consecutive CT head scans performed in the A&E and inpatient setting, as well as 50 consecutive CT head scans performed in the outpatient setting taken between January- February 2021. The results were shared with the radiology department at the district general hospital the audit was conducted in. Staff education about the need for CT head lens exclusion was the key intervention. A re-audit was conducted using the same criteria as the first audit loop for scans performed at the end of May-June 2021. The results for the re-audit were also shared with the team. Results: 1. A&E and inpatient scans: In the re-audit, 46 CT head scans included the lenses of both eyes. In the original audit, 42 CT head scans included the lenses of both eyes. 2. Outpatient scans: In the re-audit 42 CT head scans included the lenses of both eyes. In the original audit, 45 CT head scans included the lenses of both eyes. Conclusion: This audit demonstrates that equipment and patient-related factors may pose an ongoing challenge to avoiding the lens in performing a CT head scan. Educational support and awareness is needed to further reduce the radiation to the lens.
Rehabilitation of a Lower Limb Amputee
Authors:   Rehabilitation and Functional Rehabilitation Center. Mohamed V. Rabat Military Instruction Hospital, Morocco, H Mounguengui , S Khalfaoui ,   Rehabilitation and Functional Rehabilitation Center. Mohamed V. Rabat Military Instruction Hospital, Morocco
Published: February 2024

The rehabilitation of the amputee patient must be early and therfore begins immediately after the operation. In the pre-prosthetic phase, the first objective is to allow good healing and a reduction of the edema of the stump with trophic and circulatory massages ; in a second step it is a question of obtaining a toned stump by exercises of reinforcemnt and joint mobilization. In the post-prothetic phase, the aim is to integrate the prosthesis into the patient’s body diagram and to correct the gait pattern with the ultimate objective of greater patient autonomy.
Hubungan Kualitas Tidur, Durasi, dan Posisi Penggunaan Smartphone dengan Kejadian Asthenopia pada Mahasiswa Fakultas Kedokteran Universitas Islam Al-Azhar Angkatan 2022
Authors: Maharani Luh Gde Tri Cahya , Rahadianti Dian , Apriliana Denta Haritsa , Endro Pranoto
Published: February 2024

Asthenopia or eye strain (eye strain) is a collection of symptoms related to vision, eye (ocular) and musculoskeletal problems. In Indonesia, as many as 60 million people suffer from eye problems, the number increasing by one million per year. This study aims to determine the relationship between sleep quality, duration and position of smartphone use with the incidence of asthenopia in students at the Faculty of Medicine, Al-Azhar Islamic University class of 2022. This research is a type of quantitative observational research using a cross sectional design. The sampling technique is total sampling. The research sample was 98 samples according to the inclusion and exclusion criteria. The data obtained were analyzed using the Spearman rank correlation test The results of this study showed that there were 40 respondents who experienced asthenopia (40.8%), and 58 respondents who did not experience asthenopia (59.2%). Respondents who had good sleep quality were 52 people (53.1%), respondents who had poor sleep quality were 46 people (46.9%). Respondents who used smartphones for a duration of 3-8 hours in one day were 48 people (49.0%), respondents who used smartphones for a duration of >8 hours in one day were 50 people (51.0%). Respondents who more often used smartphones in a sitting position were 58 people (52.9%), and respondents who more often used smartphones in a lying position were 40 people (40.8%). There is a relationship between sleep quality and the incidence of asthenopia with a p-value of 0.000 and a correlation coefficient of -0.800. There is a relationship between the duration of smartphone use and the incidence of asthenopia with a p-value of 0.000 and a correlation coefficient of 0.731. There is a relationship between the position of smartphone use and the incidence of asthenopia with a p-value of 0.000 and a correlation coefficient of 0.916. There is a significant relationship between sleep quality, duration and position of smartphone use and the incidence of asthenopia in students at the Faculty of Medicine, Al-Azhar Islamic University class of 2022.
Analisis Strategi Marketing dalam Meningkatkan Volume Penjualan pada Es Teh Indonesia di Cabang Sepanjang, Kab. Sidoarjo
Authors: Larissa Diva Nabilah  , Budi Prabowo
Published: February 2024

This research was conducted with the aim of understanding the marketing strategies used by Es Teh Indonesia in Sepanjang Branch, Sidoarjo Regency, with a focus on increasing sales volume. This research adopted a descriptive qualitative approach as the methodology. The research location includes Es Teh Indonesia Sepanjang Branch, Sidoarjo Regency, and the participants involve the owner, employees, and consumers of the branch. The data analysis approach applied in this research is SWOT analysis, which is implemented through EFAS and IFAS tables. The results of the research analysis using IFAS and EFAS, the Indonesian Ice Tea business in Sepanjang Branch, Sidoarjo Regency has a strength factor with a total score of 2.73, while the weakness factor gets a total score of 0.40. Opportunities receive a total score of 1.85 and threats have a total score of 0.45. Based on the results of the SWOT diagram, Es Teh Indonesia is in quadrant 1, which supports an aggressive strategy (Growth oriented strategy). By referring to the SWOT diagram and matrix, the resulting strategy is the SO strategy because it has the highest score. The SO strategy supports aggressive growth (growth-oriented strategy). During the growth phase, the company can implement various strategies to maintain market growth.
Persepsi Masyarakat Kelurahan Rungkut Kidul terhadap Layanan Kelas Parenting Puspaga Balai Rw
Authors: Alfianti Garneza Merlyana , Endik Hidayat
Published: February 2024

Cases of violence against women and children are a public problem that must be answered by the government. The Surabaya City Government together with DP3APPKB Surabaya in 2017 formed the PUSPAGA program with a service center on Floor II of the former Siola Building and in 2022 it developed into PUSPAGA Balai RW with a program for prevention, risk reduction and handling of cases related to families, women and children. One of the services of the prevention program by PUSPAGA Balai RW is Parenting Classes. In implementing parenting classes there are several challenges, such as in Rungkut Kidul Village where there are still few participants attending parenting classes. So the target of this parenting class has not been achieved. This research aims to describe the perceptions of the people of Rungkut Kidul Subdistrict regarding the PUSPAGA Balai RW parenting class services. The research method used is a qualitative descriptive method with data collection techniques through interviews, observation and literature studies that are relevant to this research. The results of the research show that the perception of the Rungkut Kidul Village Community consists of 60% agreeing and 40% disagreeing with the existence of Parenting Class services. These results are deepened by public perceptions based on the 5 attributes of public service innovation according to Rogers which shows that parenting class services implemented in Rungkut Kidul Subdistrict have relative advantages, suitability, complexity and are not easy to try and easy to observe. (10pt, single line spacing, Palatino Linotype font).
Penerapan Green Banking Pada Perbankan BUMN di Indonesia: Studi Kasus pada Perbankan BUMN yang terdaftar di Bursa Efek Indonesia (BEI) Tahun 2021-2022
Authors: Devi Nur Alfiah  , Lilik Pujiati
Published: February 2024

The implementation of green banking is an effort to change the old paradigm of national development from a greedy economy to a green economy where the greedy economy is seen from the value of the gross domestic product which results in the exploitation of natural resources, while the green economy is economic growth that still pays attention to the 3Ps (people, profit and planets). The 3P concept is a sustainable development effort. Method: The research approach used is descriptive qualitative. According to Moleong (2005:6), qualitative research is research that intends to understand phenomena about what is experienced by research subjects, for example behavior, perceptions, motivations, actions, etc. holistically, and by means of descriptions in the form of words and language, on a special natural context and by utilizing various natural methods. Results: The research results show that the majority of state-owned banks in Indonesia have started steps towards implementing green banking. They have issued internal policies that support carbon emission reduction practices, such as the use of renewable energy and energy efficiency. Conclusion: the implementation of green banking in state-owned banking in Indonesia has progressed in the 2021-2022 period. Most state-owned banks have adopted practices of reducing carbon emissions, sustainable project financing, and developing environmentally friendly products and services. However, there are still challenges in implementing green banking, such as a lack of understanding and awareness of the benefits and business potential of this practice, as well as limited resources in implementing it widely.
Odd Man Out
Authors: Vaughan Dai
Published: February 2024

This annually updated reference work offers detailed advice on the diverse courses offered by UK colleges and universities in the fields of film, television, video and photography. Each entry covers syllabus, course length and the qualifications required.
KNOWLEDGE , ATTITUDE AND PRACTICES TOWARDS HIV PREVENTION AMONG ADOLESCENTS ATTENDING WAKISO HEALTH CENTRE IV, WAKISO DISTRICT. A CROSS-SECTIONAL STUDY.
Authors: NAMUKISA FELICITY , NABUKENYA SHARIFAH
Published: February 2024

Background: 
This study aims to assess the knowledge, attitude, and practices towards the prevention of HIV/AIDS among adolescents attending Wakiso Health Centre IV, Wakiso district.
 
Methodology: 
The study employed a cross-sectional study design to describe the knowledge, attitude, and practices towards prevention of HIV/AIDS among adolescents attending Wakiso Health Centre IV, Wakiso district for 10 days from 50 respondents by use of a questionnaire containing questions to assess the respondent’s demographic data, knowledge, attitude and practices towards prevention of HIV/AIDS and methods.
 
Results: 
92% of them had never heard about HIV, and all were single. The majority of the respondents 50%, knew that HIV can be prevented through abstinence, 20% by condom use, 18% by being faithful and 8% by not sharing sharp objects. A small group of the respondents 4% knew about Safe Male Circumcision (SMC) and the respondents said that abstinence, use of condoms, being faithful to your partner, and not sharing sharp objects: 48%, 20%, 16%, and 12% respectively were good methods for HIV/AIDS prevention. Respondents 48% said abstinence was the best method for HIV/AIDS prevention, 80% had tested for HIV/AIDS and 60% did SMC.
 
Conclusion: 
The study found out that adolescents had good knowledge of abstinence, use of condoms, being faithful, not sharing sharp objects, and inadequate knowledge of SMC, they had good attitudes towards abstinence, use of condoms, being faithful, and practiced abstinence, SMC, and HIV testing. The result justifies the effort put in by different stakeholders to create and promote awareness of the prevention of HIV among adolescents.
 
Recommendation: 
Wakiso Health Centre IV should ensure sex education at all times to ensure continuous awareness of HIV prevention among adolescents.
XÂY DỰNG QUY TRÌNH CHẨN ĐOÁN BIẾN THỂ ĐA HÌNH ĐƠN NUCLEOTIT RS1800629 TRÊN VÙNG KHỞI ĐỘNG CỦA GEN TNF- BẰNG KỸ THUẬT GIẢI TRÌNH TỰ SANGER VÀ PCR-RFLP
Authors: Nguyễn Hữu Ngọc Tuấn , Nguyễn Hưng Thịnh , Hồ Thị Hồng Thắm
Published: February 2024

Giới thiệu: Biến thể đa hình đơn nucleotit rs1800629 tại vị trí -308 trên vùng khởi động gen TNF-α ảnh hưởng trực tiếp đến ái lực liên kết với các yếu tố phiên mã và làm thay đổi sự biểu hiện của gen TNF-α. Ngoài kỹ thuật chuẩn mực để khảo sát là giải trình tự Sanger, kỹ thuật PCR-RFLP được phát triển giúp xác định biến thể bằng các trang thiết bị và hoá chất cơ bản, đem lại hiệu quả với độ tin cậy cao. Việc xác định thông tin về rs1800629 với chi phí tối thiểu là tiền đề thuận lợi cho các nghiên cứu về ảnh hưởng của biến thể này lên nhiều tình trạng sinh, bệnh lý quan trọng. Mục tiêu: Xây dựng bộ công cụ xác định biến thể rs1800629 trên vùng khởi động của gen TNF-α bằng kỹ thuật giải trình tự Sanger và PCR-RFLP. Đối tượng và phương pháp nghiên cứu: Xây dựng quy trình giải trình tự Sanger bằng cặp đoạn mồi tự thiết kế để khảo sát đoạn DNA dài 400-500 bp có chứa rs1800629. Tạo các dòng DNA plasmid mang lần lượt biến thể G và biến thể A của rs1800629 bằng phương pháp TA cloning. Tối ưu hoá điều kiện phản ứng PCR-RFLP sử dụng men cắt NcoI và áp dụng khảo sát rs1800629 trên 5 mẫu DNA của người tình nguyện đã biết trước kiểu gen. Kết quả: đã xây dựng thành công quy trình giải trình tự Sanger khảo sát biến thể rs1800629 bằng cặp đoạn mồi tự thiết kế; tạo 2 DNA plasmid mang alen G (wild-type) và alen A (biến thể) của rs1800629 để làm mẫu chứng; tối ưu hóa quy trình PCR-RFLP xác định rs1800629 bao gồm cắt sản phẩm PCR với enzyme NcoI và điều kiện điện di phù hợp. Toàn bộ 5 mẫu DNA của người tình nguyện có các kiểu di truyền GG (3 người), GA (1 người) và AA (1 người) được chẩn đoán đúng bằng phương pháp PCR-RFLP. Kết luận: Bộ công cụ bao gồm quy trình Sanger, quy trình PCR-RFLP và các chứng ở dạng plasmid đã được hoàn thiện để xác định biến thể TNF-α-308G/A (rs1800629) trên vùng khởi động gen TNF-α.
TÌNH HÌNH RỐI LOẠN GIẤC NGỦ Ở PHỤ NỮ MANG THAI TẠI KHOA KHÁM BỆNH, BỆNH VIỆN PHỤ SẢN THÀNH PHỐ CẦN THƠ NĂM 2023
Authors: Trần Khánh Nga , Nguyễn Minh Phương , Võ Phạm Minh Thư , Lê Thị Kim Định , Đinh Thanh Nam , Phạm Thúy Hồng , Lê Thị Bích Tuyên
Published: February 2024

Đặt vấn đề: Rối loạn giấc ngủ là hiện tượng phổ biến trong thai kỳ và ảnh hưởng đến chất lượng giấc ngủ của thai phụ. Mục tiêu: Xác định tỷ lệ, mức độ rối loạn giấc ngủ và một số yếu tố liên quan ở phụ nữ mang thai tại khoa Khám bệnh, Bệnh viện Phụ sản thành phố Cần Thơ năm 2023. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang có phân tích trên 420 thai phụ đến khám tại khoa Khám bệnh tại Bệnh viện Phụ sản thành phố Cần Thơ từ tháng 5 năm 2023 đến tháng 10 năm 2023. Xác định tỷ lệ rối loạn giấc ngủ ở thai phụ dựa vào thang điểm PSQI (Có rối loạn giấc ngủ: Tổng điểm PSQI >5 điểm). Phân tích số liệu bằng phần mềm SPSS 20.0. Kết quả: Tỷ lệ rối loạn giấc ngủ ở phụ nữ mang thai chiếm 40,2%. Nghiên cứu ghi nhận 9 yếu tố thật sự liên quan đến tình trạng rối loạn giấc ngủ của thai phụ là sống chung bố mẹ/nhà riêng với OR=2,16 (1,168 - 3,998); có bệnh đang điều trị OR=9,86 (3,41 - 28,523); sàng lọc thai bất thường OR=5,46 (2,215 - 13,467); thai phụ mong đợi giới tính của con OR=4,00 (1,199 - 13,327); thiêu tự tin làm mẹ OR=4,86 (2,736 - 8,648); áp lực diện mạo với OR=2,58 (1,502 - 4,432); áp lực công việc OR=3,79 (1,725 - 8,343); quan hệ với gia đình chồng không tốt/xấu đi OR=6,29 (3,382 - 11,702) và có biến cố trong thời gian mang thai OR=3,75 (2,117 - 6,658). Kết luận: Tỷ lệ rối loạn giấc ngủ ở phụ nữ mang thai khá cao; gây ảnh hưởng đến chất lượng cuộc sống và công việc của thai phụ
MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN KẾT QUẢ ĐIỀU TRỊ CỦA BỆNH NHÂN NHƯỢC CƠ SAU PHẪU THUẬT CẮT TUYẾN ỨC
Authors: Nguyễn Văn Tuận , Đinh Thị Lợi , Nguyễn Anh Tuấn
Published: February 2024

Mục tiêu: Phân tích một số yếu tố liên quan đến kết quả điều trị của bệnh nhân nhược cơ sau phẫu thuật cắt tuyến ức. Đối tượng và phương pháp: nghiên cứu mô tả cắt ngang từ 03/2021 đến 08/2023 trên 66 bệnh nhân nhược cơ đã phẫu thuật cắt tuyến ức tại bệnh viện Bạch Mai. Kết quả: Người bệnh ở giai đoạn bệnh nhẹ (I, IIA) theo phân loại Ossermann sau mổ cắt tuyến ức có tỉ lệ cải thiện hơn giai đoạn trung bình và nặng (IIB, III, IV): OR=164,50 (95%CI: 15,23 – 708,50). Không có triệu chứng nuốt khó, khó thở trước mổ là yếu tố thuận lợi cho kết quả cải thiện sau phẫu thuật với tương ứng OR=9,80 (95%CI: 1,20 – 80,35) và OR=5,00 (95%CI: 1,31 – 19,07). Cắt bỏ được hoàn toàn u tuyến ức, mô mỡ xung quanh và tuân thủ điều trị của bệnh nhân cho kết quả cải thiện tốt hơn sau phẫu thuật cắt tuyến ức (p<0,05). Yếu tố về giới tính, tuổi và giải phẫu bệnh tuyến ức chưa thấy có mối liên quan đến kết quả điều trị phẫu thuật. Kết luận: Bệnh nhân nhược cơ ở giai đoạn lâm sàng nhẹ sau khi mổ cắt tuyến ức sẽ có cải thiện lâm sàng tốt hơn mức độ trung bình và nặng.
NGHIÊN CỨU TÁC DỤNG ĐIỀU TRỊ VIÊM GAN VI RÚT B MẠN TÍNH CỦA BÀI THUỐC “LONG SÀI THANG” TRÊN LÂM SÀNG
Authors: Nguyễn Công Thực , Lê Hồng Phú
Published: February 2024

Mục tiêu: Nghiên cứu hiệu quả điều trị viêm gan vi rút B mạn tính của bài thuốc “Long sài thang” trên lâm sàng. Phương pháp nghiên cứu: nghiên cứu được tiến hành trên 60 bệnh nhân viêm gan vi rút B mạn tính, được ngẫu nhiên chia 2 nhóm: Nhóm điều trị gồm 32 bệnh nhân được uống thuốc sắc “Long sài thang” mỗi ngày 01 thang, ngày sắc 2 lần. Nhóm đối chứng được uống thuốc “Ích can ninh” mỗi lần 3 viên, ngày uống 2 lần. Liệu trình điều trị 3 tháng. Kết quả được đánh giá sau 2 liệu trình điều trị. Kết quả：nhóm nghiên cứu cơ bản điều trị khỏi: 56,25%，có kết quả: 37,50%，không có kết quả: 6,25%，tổng hiệu quả đạt: 93,75%. Nhóm đối chứng cơ bản điều trị khỏi: 14,29%, có kết quả: 46,43%, không có kết quả: 39,28%，tổng hiệu quả đạt: 60,72%. So sánh giữa 2 nhóm sự khác biệt có ý nghĩa thống kê với P<0.01. Kết luận: Bài thuốc “Long sài thang” là bài thuốc dựa trên những cơ sở lý luận của y học cổ truyền để điều trị viêm gan vi rút B mạn tính. Bài thuốc có hiệu quả tương đối tốt trong điều trị.
"MILLIY QONUN HUJJATLARIDA MEDIATSIYA INSTITUTINING UMUMIY TAVSIFI HAMDA USHBU SOHA DOIRASIDA ANIQLANGAN MUAMMOLAR "
Authors:   Law College of Kashkadarya Region, Jalilova Sardora
Published: February 2024

"his article covers a general description of the institution of mediation in our national legislation and the problems identified in this field. In which countries the mediation institute was first formed and how this institute developed, as well as analyses of the role of this institute in resolving disputes, are presented. In the next part of the article, the entry of the “Mediation” institute into the legislation of Uzbekistan and the chronology of the adopted normative legal documents are analyzed. And how the use of mediation in conflict resolution had a positive effect on the development of civil society in Uzbekistan. This article presents the views and analyses of national and European jurists regarding the institution of mediation. The article also mentions other methods of alternative dispute resolution. In the process of researching this topic, further development and improvement of the institution of mediation at the stage of execution of court documents A number of proposals and recommendations have been developed, taking into account the research and proposals of several legal scholars. "
INTERNET TARMOGʻIDAN AXBOROT OLISH JARAYONINI HUQUQIY JIHATDAN TARTIBGA SOLISH VA AMALGA OSHIRISHDA VUJUDGA KELADIGAN MUAMMOLAR
Authors:   Tashkent State University of Law, Ilkhombekov Jasurbek
Published: February 2024

"This article scientifically analyzes a number of problems that may arise in the process of receiving information from the global network. The main emphasis is on the issues of legal regulation of negative consequences arising from the use of the Internet. The scientific article analyzes important issues from the point of view of regulation of the right to information and implementation of the constitutional right in this regard. Based on the specific characteristics of the Internet, certain threats to the constitutional right to information are mentioned in the article. Also, directions for improvement of the legislation regulating relations established on the Internet are listed. The article discusses in detail “Spam,” which is one of the threats to the global network. Based on the content of our scientific article, different definitions and approaches of foreign scientists are reflected in the article. These analyses and opinions serve to prevent threats that may arise in the process of receiving information from the global network in our country and to improve the legislation in this field. "
ATROF-MUHITNI MUHOFAZA QILISH SOHASIDA YECHIMI KUTILAYOTGAN CHORA-TADBIRLAR
Authors:   Academic Lyceum under TSUL, Khamidova Makhbuba
Published: February 2024

"This article discusses future measures and developments for environmental solutions. This emphasizes the need for active approaches and cooperation to solve current environmental problems. The article covers the main areas of attention, such as sustainable development, transition to renewable energy sources, preservation of biodiversity, waste management, international agreements, and conferences on environmental protection. It also discusses the role of technology, education, and policy reforms in shaping solutions to environmental challenges. It is known that at present, in order to create comfortable living conditions for the population of our country, it is important to implement programmatic tasks to improve drinking water supply and wastewater systems in terms of environmental protection, rational use of natural resources, and public health. In this, drinking water and its supply and quality improvement in rural areas; protection of atmospheric air, which is considered the most important for human life; ensuring that its quality indicators are in accordance with ecological norms; land resources are material for the well-being of the population of our country; and the economic potential of our republic. It is one of our most important tasks to organize rational and productive use of water under any conditions, to use water resources rationally and economically, to increase the culture of water consumption in our society, and to form relationships of economic attitude towards water. "
"ПРАВОВЫЕ ВОПРОСЫ ВЕДЕНИЯ ИНТЕРНЕТ-РЕСУРСОВ ПРЕДСТАВИТЕЛЬНЫХ ОРГАНОВ МЕСТНОЙ ВЛАСТИ В УЗБЕКИСТАНЕ И КАЗАХСТАНЕ"
Authors:   Tashkent State University of Law, Kuatbek Gulnar
Published: February 2024

"The article provides a comparative legal analysis of the organizational and legal basis for maintaining the Internet resources of representative local authorities in Uzbekistan and Kazakhstan, ensuring the openness of their activities. As a result of the study, it was revealed that the websites of some representative local authorities do not contain all the information specified in the legislation, including information about their meetings; broadcasting of meetings is not provided; some information is not updated; and social networking opportunities are not used to broadcast meetings. It was hypothesized that in order to eliminate existing shortcomings, it is necessary to clarify the list of information on the activities of representative bodies of local government, taking into account their characteristics. The content of the relevant norms of national legislation, the interpretation of terms, and the experience of foreign countries confirmed the hypothesis. The author proposed to include in the list of information posted on the websites of representative bodies of local authorities information about official speeches and official statements of their leaders, standing committees and deputies, information messages, press releases aimed at notifying the population about the dates of meetings of representative bodies of local authorities and their working bodies, minutes of open meetings of representative bodies of local government and their working bodies, the results of hearing reports, and information on the activities of representative bodies of local government, its standing commissions, and deputies. "
Dimensionless argument: a narrow grain size range near 2 mm plays a special role in river sediment transport and morphodynamics
Authors: Parker Gary , An Chenge , Lamb Michael P. , Garcia Marcelo H. , Dingle Elizabeth H. , Venditti Jeremy G.
Published: February 2024

Abstract. The grain size 2 mm is the conventional border between sand and gravel. This size is used extensively, and generally without much physical justification, to discriminate between such features as sedimentary deposit type (clast-supported versus matrix-supported), river type (gravel bed versus sand bed), and sediment transport relation (gravel versus sand). Here we inquire as to whether this 2 mm boundary is simply a social construct upon which the research community has decided to agree or whether there is some underlying physics. We use dimensionless arguments to show the following for typical conditions on Earth, i.e., natural clasts (e.g., granitic or limestone) in 20 ∘C water. As grain size ranges from 1 to 5 mm (a narrow band including 2 mm), sediment suspension becomes vanishingly small at normal flood conditions in alluvial rivers. We refer to this range as pea gravel. We further show that bedload movement of a clast in the pea gravel range with, for example, a size of 4 mm moving over a bed of 0.4 mm particles has an enhanced relative mobility compared to a clast with a size of 40 mm moving over a bed of the same 4 mm particles. With this in mind, we use 2 mm here as shorthand for the narrow pea gravel range of 1–5 mm over which transport behavior is distinct from both coarser and finer material. The use of viscosity allows the delineation of a generalized dimensionless bed grain size discriminator between “sand-like” and “gravel-like” rivers. The discriminator is applicable to sediment transport on Titan (ice clasts in flowing methane/ethane liquid at reduced gravity) and Mars (mafic clasts in flowing water at reduced gravity), as well as Earth.
DIDACTIC FOUNDATIONS OF COMPUTER MATHEMATICAL EDUCATION FOR STUDENTS OF THE AGRICULTURAL FIELD USING IT
Authors:   Kyrgyz National Agrarian University named K.I.Skryabina, Bishkek city, Kyrgyzstan, Kudaibergenova Zh.А.
Published: February 2024

Статья показывает методику преподавания математике где требует, прежде всего, выделения его теоретических основ. Такими основами в нашем исследовании служат дидактические основы компьютерного мате¬матического образования для студентов гуманитариев с применением информационных технологий. Была обоснована необходимость изучения курса «математика» студентами аграрного направления, а также был проделан анализ современного состояния обучения математики в вузе. Были рассмотрены и проанализированы различные виды информационных технологий и средств, которые могут быть использованы при обучении курса «Математика».Модификации требований к подготовке специалистов, обусловленные эволюцией рыночной экономики в Кыргызстане, порождают необходимость обновления профессионального образования. Этот процесс включает в себя не только адаптацию к современным реалиям, но и активизацию развития личности студента, раскрытие его потенциала и внедрение информационных образовательных технологий. Использование информационных технологий при обучении математике направлено на внедрение компетентностного подхода и оптимальное управление временем. На текущем этапе развития высшего образования наблюдается профессионально-ориентированный подход к изучению предметов, сопровождаемый повышением требований к подготовке будущих специалистов. Под профессиональной компетентностью понимается целостная характеристика, отражающая способность решать профессиональные задачи в реальных условиях, основываясь на знаниях, опыте и ценностях
Los masculinos no tan “genéricos”: estudios empíricos sobre interpretaciones en español y en francés
Authors: Heap David
Published: February 2024

En el debate sobre la validez del uso de los llamados “masculinos genéricos”, los posicionamientos académicos suelen hacer referencia a la interpretación de estas formas, generalmente sin citar estudios empíricos que examinen dichas interpretaciones. Estos estudios empíricos, que suelen ser dejados de lado en el debate, buscan examinar mediante experimentos o encuestas si las formas masculinas referentes a seres humanos generan una interpretación específica (referente únicamente a varones) o genérica (referente a seres humanos de cualquier sexo). El presente artículo de revisión propone remediar esa falta de atención a los aspectos empíricos del debate, revisando primero la literatura existente sobre el español y luego comparándola con la que trata datos del francés, conformando así un aparato de evidencia empírica adecuado para la discusión y comprensión de los debates actuales sobre (por ejemplo) la pertinencia o no del lenguaje inclusivo.
LETTERATE ELOGIATE DA LODOVICO DOLCE
Authors: Boubara Ada
Published: February 2024

Lodovico Dolce nel suo trattato Dialogo di M. Lodovico Dolce della institution delle donne secondo li tre stati, che cadono nella vita humana sottolinea che per la formazione della donna, è necessario coltivare le virtù morali ma allo stesso tempo sostiene “Che la donna de’ imparar lettere” e crede che “li studi delle lettere fanno le Donne buone”. Così i suoi ragionamenti allineati alla prospettiva litterae e mores mirano a formare un testo pedagogico-educativo adatto per le donne appartenenti allo stato verginale, maritale o vedovile. Per rafforzare la sua convinzione riguardo all’importanza delle lettere come elemento essenziale dell’educazione femminile, presenta ed elogia delle donne letterate e le rappresenta come modello valoroso e rispettabile. Lodovico Dolce, tra le varie figure encomiate, esalta Cassandra Fedele, Vittoria Colonna Marchesa di Pescara, Veronica Gambara Contessa di Correggio e altre.
أثر التعاملات الإلكترونية في الموارد البشرية على العاملين (دراسة حالة الشركة السودانية للاتصالات (سوداتل) 2019 -2022م)
Authors:   أستاذ مساعد، قسم إدارة الأعمال، كلية العلوم والدراسات الإنسانية بالغاط، جامعة المجمعة، المملكة العربية السعودية, عبد المجيد طارق
Published: February 2024

تناول البحث أثر التعاملات الإلكترونية في الموارد البشرية على العاملين دراسة حالة الشركة السودانية للاتصالات (سوداتل)2019 -2022م، يشمل البحث جميع العاملين عدا فئة العمال والأمن، وتعتبر الشركة السودانية للإتصالات (سوداتل) الشركة الأم في مجال الإتصالات في السودان، تتمثل مشكلة البحث في معرفة أثر التعاملات الإلكترونية في الموارد البشرية على العاملين في الشركة والتعرف على الموارد البشرية الرقمية، ومن هنا سعى البحث إلى معرفة مدى تطبيق إدارة الموارد البشرية الإلكترونية في الشركة ويهدف هذا البحث إلى تناول مفهوم إدارة الموارد البشرية، وأهميتها وأهدافها. وإلقاء الضوء على الشركة السودانية للإتصالات وتحديد أثر تطبيقات إدارة الموارد البشرية الإلكترونية في تعزيز التميز المؤسسي، يتكون هيكل البحث من مقدمة وأربعة مباحث، يتناول المبحث الأول إدارة الموارد البشرية، أما المبحث الثاني يتحدث عن مفهوم إدارة الموارد البشرية الرقمية بينما يناقش المبحث الثالث الشركة السودانية للإتصالات (سوداتل) والمبحث الرابع يتناول الدراسة الميدانية، ومن أهم النتائج التي توصل إليها البحث أثبتت الدراسة الميدانية أن التعاملات الإلكترونية في الموارد البشرية تؤثر على العاملين، وكانت عبارات المحور المستخدمة في الإستبيان مرتفعة مع إجابات عينة البحث بمتوسط حسابي لا يقل من 4.10 في كل العبارات، ومن أهم توصيات البحث إعتماد تطبيقات إدارة الموارد البشرية الرقمية في العمل المؤسسي، توسيع نطاق تطبيق نظام تقييم الأداء الرقمي ودراسة المعوقات والحلول في التنفيذ.
Knowledge, attitude, and practices of midwives on premature rupture of membranes (PROM): A cross-sectional study in Samosir and Toba, Indonesia
Authors: Lumbanraja Sarma N. , Tobing Immanuel DL. , Santosa Heru , Nasution Mahyuddin KM. , Aritonang Evawany Y. , Ichwan Muhammad , Imelda Fatwa , Siahaan Andre MP.
Published: February 2024

Indonesia has a significantly higher maternal mortality ratio (MMR) than other countries in Southeast Asia, and infection is one of the most common causes of maternal deaths, of which premature rupture of membranes (PROM) can be the consequence of the infections. In primary healthcare settings, midwives play an important role in identifying and managing PROM appropriately; however, studies on their knowledge, attitudes, and practices related to PROM are limited. The aim of this study was to determine the midwives' knowledge, attitude and healthcare practice on PROM in Indonesia. A cross-sectional study was conducted among midwives at primary healthcare facilities in Samosir and Toba Regency, North Sumatra, Indonesia, from July to November 2022. The knowledge, attitude and practice towards PROM were assessed. Results showed that 57.5% of midwives had poor knowledge and 35.1% had poor attitude levels. There were 4.9% of midwives referred the patients immediately to the hospital. Our data indicated that aged 31−40 or 41−50 years, having a lower than bachelor degree and having a higher monthly number of referred PROM patients were significantly associated with poor knowledge compared to younger, having a bachelor degree, and lower monthly referral patient number, respectively. Similarly, younger, having higher degree and a having lower monthly referral number of PROM cases were associated with higher chances of having a sufficient-good attitude towards PROM. This study highlights that a significant percentage of midwives had poor levels of knowledge and attitude, and age, educational level and monthly referral number of PROM cases were associated with the level of knowledge and attitude.