bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral mitis group streptococci reduce infectivity of influenza A virus via acidification and H2O2 production
Authors: Okahashi Nobuo , Sumitomo Tomoko , Nakata Masanobu , Kuwata Hirotaka , Kawabata Shigetada
Published: November 2022

Members of the mitis group streptococci are the most abundant inhabitants of the oral cavity and dental plaque. Influenza A virus (IAV), the causative agent of influenza, infects the upper respiratory tract, and co-infection with Streptococcus pneumoniae is a major cause of morbidity during influenza epidemics. S. pneumoniae is a member of mitis group streptococci and shares many features with oral mitis group streptococci. In this study, we investigated the effect of viable Streptococcus oralis, a representative member of oral mitis group, on the infectivity of H1N1 IAV. The infectivity of IAV was measured by a plaque assay using Madin-Darby canine kidney cells. When IAV was incubated in growing culture of S. oralis, the IAV titer decreased in a time- and dose-dependent manner and became less than 100-fold, whereas heat-inactivated S. oralis had no effect. Other oral streptococci such as Streptococcus mutans and Streptococcus salivarius also reduced the viral infectivity to a lesser extent compared to S. oralis and Streptococcus gordonii, another member of the oral mitis group. S. oralis produces hydrogen peroxide (H2O2) at a concentration of 1–2 mM, and its mutant deficient in H2O2 production showed a weaker effect on the inactivation of IAV, suggesting that H2O2 contributes to viral inactivation. The contribution of H2O2 was confirmed by an inhibition assay using catalase, an H2O2-decomposing enzyme. These oral streptococci produce short chain fatty acids (SCFA) such as acetic acid as a by-product of sugar metabolism, and we also found that the inactivation of IAV was dependent on the mildly acidic pH (around pH 5.0) of these streptococcal cultures. Although inactivation of IAV in buffers of pH 5.0 was limited, incubation in the same buffer containing 2 mM H2O2 resulted in marked inactivation of IAV, which was similar to the effect of growing S. oralis culture. Taken together, these results reveal that viable S. oralis can inactivate IAV via the production of SCFAs and H2O2. This finding also suggests that the combination of mildly acidic pH and H2O2 at low concentrations could be an effective method to inactivate IAV.
Sulfur dioxide emissions curbing effects and influencing mechanisms of China’s emission trading system
Authors: Yao Fengge , Li Lin , Zhong Shen
Published: November 2022

The emissions trading system, a crucial and fundamental system reform in the environmental resources field of China, was established to promote the continuous and effective reduction of total emissions of major pollutants. In this context, based on the panel data of 285 Chinese cities (except Tibet) from 2004 to 2018, this paper uses the quasi-experimental method of Difference in Difference to assess the effect of the emissions trading system introduced on sulfur dioxide emissions of China and the transmission mechanism. The article generates several intriguing findings. (1) The emissions trading system has a significant suppressive effect on sulfur dioxide emissions. (2) Mechanistic tests show that the emissions trading system can effectively suppress sulfur dioxide emissions by reducing government intervention, stimulating green patent innovation, and improving resource use efficiency, in which green utility patents have a masking effect. (3) From the east, central and west divisions, the emissions trading system has a significant suppression effect on sulfur dioxide emission in the eastern and central regions, and the eastern region is better than the central region. (4) In terms of factor endowment, the emissions trading system has a significant suppression effect on sulfur dioxide emissions in both resource-based and non-resource-based cities, with non-resource-based cities outperforming resource-based cities; while within resource-based effect exists only in regenerative cities. (5) The emissions trading system has a significant suppression effect on sulfur dioxide emissions in old and non-old industrial base cities in industrial base zoning. The suppression effect in non-old industrial base cities is better than that in old industrial base cities. This paper provides empirical evidence for evaluating the emissions trading system at the provincial level in China and suggests policy recommendations for selecting government tools to effectively curb sulfur dioxide emissions. Although the emissions trading system has made an outstanding contribution to sulfur dioxide emissions reduction, there is still much space for further development of potential emission reductions.
HCLC-FC: A novel statistical method for phenome-wide association studies
Authors: Liang Xiaoyu , Cao Xuewei , Sha Qiuying , Zhang Shuanglin
Published: November 2022

The emergence of genetic data coupled to longitudinal electronic medical records (EMRs) offers the possibility of phenome-wide association studies (PheWAS). In PheWAS, the whole phenome can be divided into numerous phenotypic categories according to the genetic architecture across phenotypes. Currently, statistical analyses for PheWAS are mainly univariate analyses, which test the association between one genetic variant and one phenotype at a time. In this article, we derived a novel and powerful multivariate method for PheWAS. The proposed method involves three steps. In the first step, we apply the bottom-up hierarchical clustering method to partition a large number of phenotypes into disjoint clusters within each phenotypic category. In the second step, the clustering linear combination method is used to combine test statistics within each category based on the phenotypic clusters and obtain p-values from each phenotypic category. In the third step, we propose a new false discovery rate (FDR) control approach. We perform extensive simulation studies to compare the performance of our method with that of other existing methods. The results show that our proposed method controls FDR very well and outperforms other methods we compared with. We also apply the proposed approach to a set of EMR-based phenotypes across more than 300,000 samples from the UK Biobank. We find that the proposed approach not only can well-control FDR at a nominal level but also successfully identify 1,244 significant SNPs that are reported to be associated with some phenotypes in the GWAS catalog. Our open-access tools and instructions on how to implement HCLC-FC are available at https://github.com/XiaoyuLiang/HCLCFC.
The effect of mindfulness on the inflammatory, psychological and biomechanical domains of adult patients with low back pain: A randomized controlled clinical trial
Authors: Diez Gustavo G. , Anitua Eduardo , Castellanos Nazareth , Vázquez Carmelo , Galindo-Villardón Purificación , Alkhraisat Mohammad H.
Published: November 2022

Objective

This study aims to study the effect of mindfulness-based program on the psychological, biomechanical and inflammatory domains of patients with chronic low back pain.

Methods

A multicentre randomized and controlled clinical trial of parallel groups in patients with chronic low back pain between March 2019 to March 2020. Participants with no experience in mindfulness based intervention, were randomized to receive (36 patients) or not (34 patients) mindfulness-based stress reduction program for chronic back pain (MBSR-CBP). The program was performed in 9 sessions. Patients with chronic low back pain due to symptomatic discopathy (degenerative disc disease or herniated disc) were included. The principal outcome was changes in the blood level of cortisol and cytokines (tumor necrosis factor- α (TNF- α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and interleukin-17 (IL-17)). Secondary outcomes (psychological factors, pain, and quality of life) were measured by validated questionnaires.

Results

Of the 96 randomized patients, 70 who completed the study were included in the analysis (mean [range] age: 53 [33–73] years; 66% females). MBSR-CBP stopped the increase in cortisol, and reduced pro-inflammatory cytokine IL-1β (p = 0.05). It reduced depression (p = 0.046) and stress (p = 0.0438), perceived pain (p < 0.0001), and limitations related to health (p < 0.0001). It also increased the physical function (p = 0.002) and sleep quality (p = 0.05). Furthermore, it significantly increased life satisfaction (0.006), well-being (p = 0.001) and vitality (p < 0.0001). It also increased self-compassion (p < 0.0001) and significantly reduced the overidentification (p<0.0001) and catastrophization (p = 0.002).

Conclusions

MBSR-CBP could be part of a multidisciplinary approach in the management of patients suffering from chronic low back pain.
Global Media Ethics and the Digital Revolution, Noureddine Miladi (ed.) (2022)
Authors: Abdel Haleem Harfiyah Ball
Published: November 2022

Review of: Global Media Ethics and the Digital Revolution, Noureddine Miladi (ed.) (2022)

Abingdon, Oxford and New York: Routledge (Taylor and Francis Group), 278 pp.,

ISBN 971-1-03206-214-3, h/bk, £120
Advances in Neural Stem Cell Therapy for Spinal Cord Injury: Safety, Efficacy, and Future Perspectives
Authors: Lee Sungjoon , Nam Hyun , Joo Kyeung-Min , Lee Sun-Ho
Published: November 2022

Spinal cord injury (SCI) is a devastating central nervous system injury that leads to severe disabilities in motor and sensory functions, causing significant deterioration in patients’ quality of life. Owing to the complexity of SCI pathophysiology, there has been no effective treatment for reversing neural tissue damage and recovering neurological functions. Several novel therapies targeting different stages of pathophysiological mechanisms of SCI have been developed. Among these, treatments using stem cells have great potential for the regeneration of damaged neural tissues. In this review, we have summarized recent preclinical and clinical studies focusing on neural stem cells (NSCs). NSCs are multipotent cells with specific differentiation capabilities for neural lineage. Several preclinical studies have demonstrated the regenerative effects of transplanted NSCs in SCI animal models through both paracrine effects and direct neuronal differentiation, restoring synaptic connectivity and neural networks. Based on the positive results of several preclinical studies, phase I and II clinical trials using NSCs have been performed. Despite several hurdles and issues that need to be addressed in the clinical use of NSCs in patients with SCI, gradual progress in the technical development and therapeutic efficacy of NSCs treatments has enhanced the prospects for cell-based treatments in SCI.
The Meme Radar
Authors: Kallius Annastiina , Adriaans Rik
Published: November 2022

This article examines the social media practices through which young Hungarians deliberate the workings of truth and the meanings of liberalism under Viktor Orbán’s authoritarian regime. Noting similarities between ubiquitous government propaganda billboards and the aesthetics of parodic social media content, these youth increasingly perceive everyday situations as internet memes. Navigating generational differences, class antagonisms, and rural-urban divisions, for them, seeing the world as a meme anchors the youth’s sense of truth and untruth and liberal identity in a polarized political field. We trace the everyday practices of montage through which conspiratorial billboard campaigns and the parodic forms of internet memes become linked, and observe how the visual, visceral, and networked sensibilities of meme culture help neutralize illiberal propaganda by turning it into a source of the self. 

KIVONAT

Írásunkban azokat a közösségi média gyakorlatokat vizsgáljuk, amelyeken keresztül a magyar fiatalok értelmezik és reflektálnak arra, hogy mi az igazság és mit jelent a liberalizmus Orbán Viktor autoriter rezsimében. A mindent átható kormánypropaganda óriásplakátjai és a parodisztikus közösségi médiatartalmak esztétikája közötti hasonlóságot felismerve, ezek a fiatalok egyre inkább internet mémekben ragadják meg a hétköznapok történéseit. A generációs különbségek, a társadalmi osztályok közti antagonizmusok és a vidék-város megosztottság gondolati terében egyensúlyozva, a világot mémeken keresztül látva, ezek segítenek a fiataloknak eligazodni igazság- és valótlanság között, és irányt mutatnak liberális identitásuk megéléséhez egy kiélezett politikai erőtérben. Azokat a mindennapi mém-gyártó gyakorlatokat követjük nyomon, amelyeken keresztül a konspiratív plakátkampányok és a parodisztikus internet mémek összekapcsolódnak, megfigyelve, hogy a mémkultúra vizuális, zsigeri és hálózatba rendeződő érzékenysége hogyan semlegesíti az illiberális propagandát azáltal, hogy az önkifejezés és öndefiníció forrásává teszi.
Применения принципов реинжиниринга бизнес-процессов в рамках создания единого информационного пространства предприятия
Authors:   Уфимский государственный авиационный технический университет, Куликов Г.Г. , Гиндуллина Т.К. ,   Уфимский государственный авиационный технический университет, Капустин В.Н. ,   ООО «АЙПЛ Консалтинг», Демченко М.С. ,   Уфимский государственный авиационный технический университет, Набиев Р.Р. ,   ООО «АЙПЛ Консалтинг»
Published: November 2022

В данной статье рассматриваются вопросы практического применения принципов реинжиниринга бизнес-процессов при реализации проекта по совершенствованию автоматизированной системы оперативного управления литейным производством ПАО «ОДК-УМПО» (Уфимское моторостроительное производственное объединение) при внедрении ERP Infor LN. Описана сущность применения принципов «разработка различных вариантов проекта», «рационализация горизонтальных связей». Применение принципа «разработка различных вариантов бизнес-процессов» позволяет реализовать учет разделения одной партии отливок на несколько частей при выполнении технологических операций. Применение принципа «рационализация горизонтальных связей» создает условия для формирования единого информационного пространства управления литейным производством. Это пространство связано с вопросами инженерного проектирования, технологического проектирования, реализации и управления производственными процессами. Несмотря на то, что реинжиниринг предполагает «революционное» изменение бизнес-процессов, использование его принципов на эволюционном пути развития так же экономически эффективно и в то же время снижает риски провала проекта. Так, моделирование бизнес-процесса управления финишными операциями при изготовлении отливок, выполненное в BPMN 2.0, показало сокращение продолжительности процессов более чем на 15 %. Цель исследования: построение модели управления литейным производством в едином информационном пространстве предприятия с использованием принципов реинжиниринга бизнес-процессов в аспекте управления готовыми операциями. Материалы и методы. Применение принципов реинжиниринга бизнес-процессов к управлению отделочными работами литейного производства, BPMN-моделирование. Результаты. С применением принципа рационализации горизонтальных связей становится возможной передача данных из ERP-системы в CAD-систему и наоборот. Формируется единое информационное пространство управления предприятием, позволяющее объединить все функции управления. Заключение. В связи с этим появляется возможность выявить «узкие» места в управлении литейным производством и принять меры по их устранению. Повысить уровень обмена информацией между всеми подразделениями предприятия, что создаст замкнутую схему управления производством и значительно повысит эффективность использования Infor LN.
ANALISIS KETEPATAN KEBIJAKAN PEMBINAAN UMKM DI KECAMATAN KEDAWUNG KABUPATEN SRAGEN
Authors: Santoso Slamet , Jati Nur Cahyo Kuncoro Rahmad
Published: November 2022

Micro, Small, Medium Enterprise (MSME) is a pioneering populist-based business that is developing quite rapidly. Micro, Small and Medium Enterprises are also one of the factors that can create economic growth. The development of MSMEs is a reaction from the industrial revolution in the 4th stage which increasingly emphasizes the mechanization system in the production process. Fostering MSMEs is one way to maintain the existence of developing MSMEs and can bring new MSMEs. The Sragen Regency Government has poured efforts on the Sragen Regency Regulation No. 3 of 2013 concerning MSMEs. Kedawung District, Sragen Regency is one of the targets of the policy. Kedawung District itself is also famous for its rich natural resources such as extensive rubber trees. This study aims to analyze the accuracy of the implement MSME coaching policies in Kedawung District, Sragen Regency. The research method used was a descriptive qualitative type with informants including the Sragen Regency Industry and Trade Office, the Sragen Regency Cooperative and MSME Office, the FEDEP, the Private sector, as well as several MSME actors who received guidance. The results of the study showed that the accuracy of the implement the general coaching policy for MSMEs was found to be in accordance with applicable regulations, mainly supported by cooperate between actors. The collaboration was carried out between the private sector, the agency, FEDEP and the direct participation of the local government, although there were still obstacles in it related to the regulations above, less than the ideal role of the local government such as the government in the sub-district and village or village environment. Awareness of SMEs who are less pro-actively influencing the performance of the training carried out.
EVALUASI PELAPORAN KEUANGAN TAHUN 2016-2018 DENGAN MODEL CIPP (CONTEXT, INPUT, PROCESS, PRODUCT) PADA PUSAT PENELITIAN KEBIJAKAN PENDIDIKAN DAN KEBUDAYAAN
Authors: Herawati A Rina , Kusumawati Hasti
Published: November 2022

This research aims to investigate the quality implementation of financial reporting in Research Centre for Educational and Cultural Policies, Research and Development Agency, Ministry of Education and Culture, using CIPP (Context, Input, Process, Product) evaluation model. Focus of the problem researched is how to evaluate the financial reporting in Research Centre for Educational and Cultural Policies, Research and Development Agency, Ministry of Education and Culture. The descriptive methodology was used with qualitative approach. Data collection techniques were interview and document review. Research results are as follows: (1) Context Aspect is conformity between purpose and target in financial reporting in Centre for Policy Research with Government Regulation No. 71 Year 2010 concerning Standard for Government Accounting for the interests of accountability, management, transparency, and performance evaluation; (2) Input Aspect is resource in financial reporting, including human resource and facilities and infrastructure (computer, internet network, and office facilities) which have been adequate to support timely financial reporting; (3) Process Aspect is in the process of financial reporting implementation in which the problems found are late BMN reporting, BMN recording which is not orderly administration, the lack of coordination and communication among planner, executor, and application operator, the role of leader which is is still inadequate, and SPI supervision which is not yet optimal; and (4) Product Aspect is financial statement in Research Centre for Educational and Cultural Policies which is relevant, reliable, and useful as source of information in management decision. Suggestions to be given are as follows: (1) Periodic coordination between stakeholders; (2) Intensive evaluation of employee performance in the process of financial reporting; (3) Suggesting SPI task as a supervisor in internal control as functional position; and (4) Recruiting more employees as administrator and operator in BMN application
PUBLIC ENGAGEMENT IN AGRARIAN CONFLICT RESOLUTION
Authors: --- Thetanaya --- , Thetanaya Thetanaya
Published: November 2022

AbstrakProblem: Konflik pertanahan sudah sejak dulu menjadi pemasalahan yang tak kunjung usai. Bahkan di masa pandemi, KPA mencatat peningkatan konflik agraria yang dipicu perebutan lahan, baik untuk tujuan ekonomi, maupun untuk tujuan kepentingan umum. Penelitian bertujuan mempelajari model kebijakan yang selama ini dilaksanakan oleh pejabat daerah sehingga mampu menjawab pertanyaan mengapa konflik pertanahan tidak kunjung selesai.Temuan: Kebijakan distribusi lahan merupakan kebijakan warisan jaman kolonial. Kebijakan ini dipergunakan hingga era kemerdekaan hingga era reformasi. Meskipun sudah ada kebijakan desentralisasi, namun penyusunan rencana tata ruang wilayah tak kunjung selesai dan diperparah klaim tumpeng tindih lahan antar kementerian. Sementara masyarakat ada yang sudah bermukim di lahan tak bertuan. Hal ini menimbulkan celah kekosongan hukum ketika terjadi konflik warga dengan perusahaan. Berdasarkan temuan beberapa literatur, pemerintah daerah selalu mengupayakan penyelesaian konflik melalui jalan tengah yang sering diingkari di kemudian hari oleh pihak korporasi. Pemerintah daerah perlu menerapkan penyelesaian konflik dengan melibatkan para pemangku kepentingan secara kolaboratif, bahkan pelibatan akademisi perlu diikutsertakan dalam pemberdayaan masyarakat desa.   Keywords: konflik agrarian, model kebijakan, komunikasi, kolaborasi, musyawarah, mufakat
Nutzungsforschung in der Universitätsbibliothek der Freien Universität Berlin: Werkstattbericht zur Beteiligung am internationalen Projekt „Cancelling the Big Deal“
Authors: Harnisch Franziska , Kowalak Mario , Wagner Cosima
Published: November 2022

Wie haben die Veränderungen beim Zugang zu elektronischen Fachzeitschriften die Forschungserfahrung und Wahrnehmung der Forschenden bezüglich ihrer Universitätsbibliothek beeinflusst? Welche Strategien wenden Forschende an, um sich Zugang zu den betreffenden Inhalten zu verschaffen? Wie können Bibliotheken diese Prozesse analysieren und bewerten? Die Beantwortung dieser Fragen ist nicht nur grundlegend für eine fachspezifische bzw. fachübergreifende Ausgestaltung von Serviceangeboten im Bereich Open Access, sondern auch für das Selbstverständnis von Universitätsbibliotheken als Partnerinnen von Forschung und Lehre. Die Autorinnen und Autoren berichten in Form eines Werkstattberichts über die Durchführung einer qualitativen Studie in Kooperation mit Ithaka S+R sowie die Impulse, die sie für ihre bibliothekarische Arbeit daraus mitgenommen haben.
Die Hochschulbibliotheken in NRW auf dem Weg in die Alma-Cloud
Authors: Plaum Christiane
Published: November 2022

Das Implementierungsprojekt der NRW-Hochschulbibliotheken und einiger hbz-Verbundteilnehmer aus Rheinland-Pfalz ist im Sommer 2022 noch im vollen Gange. In der Vergangenheit haben hier bereits andere Verbünde und Hochschulbibliotheken von ihrem erfolgreichen Umstieg auf die Alma-Plattform von Ex Libris berichtet. Deswegen legen wir den Schwerpunkt auf die besonderen Herausforderungen in unserem Projekt und berichten sowohl von dem Erreichten, wie zum Beispiel die Meilensteine Go-Live der ersten und zweiten Wave, als auch von den Unwägbarkeiten, die bis zum Projektende im Jahr 2023 noch vor uns liegen. Grundsätzlich sind wir zuversichtlich, mit dem Umstieg auf eine einheitliche bibliothekarische Infrastruktur eine sehr gute Balance von Zentralisierung und Dezentralisierung gefunden haben. Die zentralen Dienste des hbz, wie z. B. die Verwaltung der E-Ressourcen, Fernleihe etc., schaffen Arbeitserleichterungen für alle Beteiligten und nicht zuletzt bietet das hbz den Alma-First-Level-Support nach Go-Live. Die Bibliotheken können trotzdem individuell entscheiden, wie sie ihre lokale Ebene gestalten und welche Systeme sie in Eigenregie anbinden. Aufgrund des straffen Zeitplans und der Dichte der Aufgaben, sowohl für das hbz als auch für die lokalen Projektteams, gelingen all diese Arbeiten nur, wenn die Fachexperten aus den verschiedenen Bereichen konstruktiv und über ihre eigene Institution hinaus in Arbeitsgruppen zusammenwirken. Das zahlt sich bis dato aus.
Den Lern- und Bildungsraum Hochschulbibliothek gestalten. Zwei neue Campusbibliotheken an der TH Köln
Authors: Busch Margarete
Published: November 2022

Die Hochschulbibliothek der TH Köln hat sich im Rahmen von zwei Neubauprojekten zwischen 2016 und 2022 intensiver mit den veränderten Anforderungen von Studierenden an die Nutzung von Bibliotheksräumen im Kontext einer zunehmenden Digitalisierung von Studium und Lehre und der Anforderung, forschendes Lernen durch geeignete Raumgestaltung zu unterstützen, befasst. Der folgende Beitrag stellt Erkenntnisse und Schlussfolgerungen für beide Bauprojekte einander gegenüber.
In-line measurements of the physical and thermodynamic properties of single and multicomponent liquids
Authors: Bissig Hugo , Büker Oliver , Stolt Krister , Graham Emmelyn , Wales Leslie , Furtado Andreia , Moura Sara , Metaxiotou Zoe , Lee Seok Hwan , Kartmann Sabrina , Groenesteijn Jarno , Lötters Joost C.
Published: November 2022

Microfluidic devices are becoming increasingly important in various fields of pharmacy, flow chemistry and healthcare. In the embedded microchannel, the flow rates, the dynamic viscosity of the transported liquids and the fluid dynamic properties play an important role. Various functional auxiliary components of microfluidic devices such as flow restrictors, valves and flow meters need to be characterised with liquids used in several microfluidic applications. However, calibration with water does not always reflect the behaviour of the liquids used in the different applications. Therefore, several National Metrology Institutes (NMI) have developed micro-pipe viscometers for traceable inline measurement of the dynamic viscosity of liquids used in flow applications as part of the EMPIR 18HLT08 MeDDII project. These micro-pipe viscometers allow the calibration of any flow device at different flow rates and the calibration of the dynamic viscosity of the liquid or liquid mixture used under actual flow conditions. The validation of the micro-pipe viscometers has been performed either with traceable reference oils or with different liquids typically administered in hospitals, such as saline and/or glucose solutions or even glycerol-water mixtures for higher dynamic viscosities. Furthermore, measurement results of a commercially available device and a technology demonstrator for the inline measurement of dynamic viscosity and density are presented in this paper.
Herausforderungen und Perspektiven der Wortschreibung: Tarifit auf Facebook und das Standard-Amazigh im Vergleich
Authors: Tahiri Naima
Published: November 2022

The Berber languages of Morocco – regionally distributed differently: Tarifit, Tamazight and Tashelhit – were subjected to a standardization process only at the beginning of the 21st century. The so-called Amazigh emerged as a standard language. The Institut Royal de la Culture Amazighe, founded in 2001 specifically for the preservation and promotion of Berber, was given the task of initiating and controlling the standardization process. In 2008, a reference grammar of standard Amazigh was published, which will be examined more closely in the following article with regard to the orthographic specifications for the spelling of nominal units. In doing so, the critical examination of orthography will be conducted in a relatively unconventional manner. The written form of Tarifit used within a Facebook group will be analyzed in order to compare the word spellings with the spelling rules of the standard Amazigh grammar. Tarifit is used extensively in social networks in certain contexts and the preferred writing system is Latin. The French-language grammar description of the standard Amazigh uses for the object language level the so-called Tifinagh. However, this writing system is hardly used in Moroccan society not only due to a lack of acceptance. Likewise, the use of standard Amazigh in society is almost non-existent. Lay transcriptions in social networks can be very informative with regard to word spellings. The grammar description for the standard Amazigh can be criticized from different perspectives and is in urgent need of a linguistically based revision.
Decision-theoretic foundations for statistical causality: Response to Pearl
Authors: Dawid Philip
Published: November 2022

I thank Judea Pearl for his discussion of my paper and respond to the points he raises. In particular, his attachment to unaugmented directed acyclic graphs has led to a misapprehension of my own proposals. I also discuss the possibilities for developing a non-manipulative understanding of causality.
Determining the parameters of noise pollution in the central area of the Almaty city in Kazakhstan
Authors: Jasim Saade Abdalkareem , Rudiansyah Mohammad , Ongdashkyzy Ongdash Ainur , Taban Talib Zeedan , Chupradit Supat , Iswanto A. Heri , Suhayb Mustafa K. , Falih Khaldoon T. , Alshahrani Najim Z. , Mustafa Yasser Fakri
Published: November 2022

One of the adverse effects of industrialization is noise pollution, which disturbs the mental health and tranquility of urban residents and is the source of numerous social tensions. Twenty stations in the central areas of Almaty with varying uses during the morning, afternoon, and evening rush hours were measured for this study. The objectives of this paper include determining sound indices, identifying potential sound sources, and calculating the relative contribution of each to the overall urban noise level. Additionally, 400 questionnaires were distributed to individuals to assess noise pollution’s effects on individuals. The average maximum value of TNI (Traffic Noise Index) in residential and commercial use is 85.4 dB(A), and the maximum value of Leq (Equivalent continuous sound level) in commercial use is 86 dB(A). In addition, 50 city bus drivers were examined to determine the impact of noise in this environment. The results revealed that as Leq increases, the number of unsafe acts increases. The questionnaires revealed that people are significantly more dissatisfied with noise pollution at stations with higher sound levels.
Wet creping of paperboard
Authors: Tanaka Atsushi , Ketoja Jukka A. , Lehmonen Jani , Turpeinen Tuomas , Kouko Jarmo , Kiiskinen Harri
Published: November 2022

We describe a wet creping approach, applicable not only for softwood kraft papers in the grammage range of 30–120 g/m2but also for 300 g/m2CTMP board. Creping of board requires a certain level of deformability in the material, which is controlled by its solids content. The concept was tested at laboratory scale using a device on which temperature, blade angle and line load could be adjusted. The sample density was decreased by creping due to small-scale delamination of the structure, leading to separate inner layers with a wavy appearance. The strain at break was remarkably increased and agreed well with the theoretical estimate based on the crepe ratio and the breaking strain of the uncreped sample. Simultaneously, tensile strength was reduced by creping. In terms of tensile strength and stretch, 60–70 % solids content during creping was optimal for the tested board.
Performance, Collaboration, and the Politics of Place
Authors: Schönfeldt-Aultman Scott M. , Klein Emily B. , Viola Michael J. , Healey Josh
Published: November 2022

This transcript shares a May 2019 conversation with Josh Healey, an Oakland-based writer, artist, and filmmaker, about his work with the independent web series The North Pole. The interview was conducted with several members of the Ethnic Studies faculty from Saint Mary’s College of California. Healey explains the connections he sees between politics, humor, and storytelling, and delves into the strategies and struggles of the creative process, including the value of personal relationships, collaboration, and representing real people and real life.
Designing Joyful Learning
Authors: Scapp Ron
Published: November 2022

This interview highlights Samantha Antione-Purcell’s work in bringing a new educational model to Grenada. Antione-Purcell describes her journey into teaching and educational leadership, and the creation of a new collaborative school, The St. George’s Institute. The interview is conducted by Ron Scapp.
New species of the genus Rhodorhipha Laguerre, 2018 (Lepidoptera: Arctiini) from Peruvian Amazon
Authors: Grados Juan
Published: November 2022

A new species Rhodorhipha dalyi sp. nov. from Peru (Tambopata river, Madre de Dios, Peru) is described and illustrated. The species is part of a complex of similar species related to R. subflammans (Rothschild).
A retrospective study on the prevalence of tinea (ringworm) infections in patients who attended halibet national referral hospital, dermatologic clinic from 2014 to 2018 Asmara, Eritrea.
Authors: Qelit Yohanes
Published: November 2022

Introduction: Skin fungal diseases pose a significant burden on the health care system of a country. Superficial fungal skins infections are caused by dermatophytes. Dermatophytes are classified as one of the groups of Fungi. The three genera of dermatophytes grow in keratinized environments such as hair, skin, and nails. Anthropophilic dermatophytes are restricted to human hosts; zoophilic dermatophytes to pets, livestock, and horses; and geophilic dermatophytes, from soil, only occasionally infect humans and animals. Objective: The aim of the study was to determine the prevalence of Tinea (Ringworm) infections in patients who attended Halibet National Referral Hospital, Dermatologic Clinic from 2014 to 2018 Asmara, Eritrea. Methods: A five year retrospective study on the prevalence of superficial fungal skin infections was conducted in the outpatient department in patients who attended dermatologic Clinic at Halibet National Referral Hospital, Asmara, Eritrea from 2014 to 2018. A review of clinical cards / medical records was conducted and the data was analyzed using SPSS version 22. Results: During the five years period (2014- 2018) the Dermatology clinic of Halibet Hospital had a total visit of 32,153 patients who were treated as outpatients. Out of these patients who came from the whole country as referral and self-referral, 5524 (17.18%) were diagnosed clinically as cases with different types of Tinea infections. The number of females (2791, 50.5%) and males (2732, 49.5%) was almost the same. The highly infected body site was the head (77.5%) followed by the body (11%), face (6%) and hand (3%). And the most common type of Tinea that clinically identified was Tinea capitis 58% (n=4426) as it is compared to other types of Tinea. The other types of Tinea species that were found as comorbid with others were Tinea faciei, Tinea corporis, Tinea pedis, Tineamanuum, Tinea cruris and Tineaunguium as prevalent as 26.8%, 6.6%, 3.5%, 3.4%, 1.2% and 0.3%, respectively Conclusion: The study concludes the overall prevalence of superficial Tinea skin fungal infections was found to affect mostly the head (77.0%), body (11%), face (6%) and hand (3%), foot (2%) and groin (1%), respectively. And the most common type of Tinea that clinically identified was Tinea capitis 58%. The other types of Tinea species ere found as comorbid with others Tinea faciei, Tinea corporis, Tinea pedis, Tineamanuum, Tinea cruris and Tineaunguium as prevalent as 26.8%, 6.6%, 3.5%, 3.4%, 1.2% and 0.3%, respectively.
Mechanical Ventilation and Hospital-Acquired Venous Thromboembolism Among Critically Ill Children
Authors: Sochet Anthony Alexander , Havlicek Elizabeth Ellen , Faustino E. Vincent S. , Goldenberg Neil Andrew
Published: November 2022

OBJECTIVES

To estimate the occurrence of, and evaluate associations between, hospital-acquired venous thromboembolism (HA-VTE) and invasive mechanical ventilation (MV) among children hospitalized in the PICU.

METHODS

We performed a multicenter, retrospective cohort study comparing HA-VTE frequencies among subjects <18 years of age hospitalized in the PICU from January 2018 through December 2019 among 47 participating centers, via the Pediatric Health Information Systems registry. We excluded perinatal encounters, those with VTE present at admission, and those with observational status. The primary outcome was the proportion of HA-VTE events before hospital discharge, including extremity deep venous thrombosis, pulmonary embolism, and organ-specific deep venous thrombosis. The HA-VTE frequencies were compared using χ2 tests. The association between HA-VTE and MV was investigated via multivariable logistic regression, adjusting for previously described VTE risk factors.

RESULTS

Of the 205 231 PICU encounters identified for study, 70 829 (34.5%) underwent MV. The occurrence of HA-VTE was 2.2% and was greater among children who received, versus did not receive, MV (4.4% versus 1.1%, P < .001). Multivariable logistic regression revealed significant association between MV and HA-VTE (odds ratio 2.51, 95% confidence interval 2.33–2.69; P < .001).

CONCLUSIONS

In this multicenter, retrospective, registry-based cohort study, HA-VTE were diagnosed in 2.2% of critically-ill children, and after adjustment for central venous catheterization, MV independently increased the risk of HA-VTE 2.5-fold. These findings warrant prospective validation to inform the design of future risk-stratified clinical trials of thromboprophylaxis in critically-ill children.
Management of Atrial Fibrillation Using Immunoglobulin Free Light Chains, Novel Biomarkers of Inflammation
Authors: Matsumori Akira
Published: November 2022

AF is the most common cardiac arrhythmia. There is growing evidence that inflammatory mechanisms play an important role in its pathogenesis; inflammasome activation contributes to the onset and progression of AF. An increase in NOD-like-receptor-pyrin domain-containing-3 (NLRP3) inflammasome activation releases proinflammatory cytokines that activate nuclear factor (NF)-κB, which regulates the production of immunoglobulin free light chains (FLCs). Serum FLC levels are increased in patients with AF, and FLCs are biomarkers of inflammation. Inflammasomes and NF-κB may be targets for anti-inflammatory strategies to prevent and treat AF when FLC levels are elevated. This review discusses the role of inflammation in the pathogenesis of AF, as well as FLCs as novel inflammatory biomarkers for the management of AF.
Educação em saúde e final de vida no hospital
Authors: Cordeiro Franciele Roberta , Dos Santos Marques Rayssa , De Oliveira Silva Kaliana , Cruz Martins Monike , Vestena Zillmer Juliana Graciela , Sant'Ana Tristão Fernanda
Published: November 2022

Objetivo: identificar ações de educação em saúde direcionadas às pessoas em final da vida e seus cuidadores, informais e formais, no hospital, além de avaliar o nível de evidência de tais ações.
Síntese do conteúdo: o estudo foi realizado entre dezembro de 2019 e janeiro de 2020, nas bases de dados Web of Science, Scopus e MEDLINE. Identificaram-se 6.762 artigos, dos quais 42 integram a análise por serem artigos originais ou de revisão escritos em português, espanhol, inglês ou francês; a amostra dos estudos foi composta por pacientes maiores de 19 anos, com doença avançada e/ou em final de vida ou cuidadores ou profissionais de saúde. Os dados foram agrupados por similaridade do tema das ações, conforme Polit e Beck, e o nível de evidência avaliado segundo Melnyk e Fineout-Overholt. O vídeo foi a ação com maior força de recomendação, seguida por cartilhas. As unidades temáticas foram “Ações para o controle da dor”, “Narrativas sobre o final da vida”, “Planejamento de cuidados”, “Dialogando sobre os cuidados paliativos” e “Comunicação e final de vida”.
Conclusões: ações de educação em saúde no final da vida devem considerar as tecnologias da informação e da comunicação, além das condições socioculturais, clínicas e cognitivas dessa etapa do adoecimento.
Transpersonal care through Reiki: Experiences of family members of children with sickle cell disease
Authors: Morbeck Amarry Dantas , Costa Cerqueira Erika Anny , Lima Falcão do Vale Paulo Roberto , Harman Watson Margaret Jean , De Santana Carvalho Evanilda Souza
Published: November 2022

Objective: To understand the experiences of family members of children with sickle cell disease during transpersonal nursing care meetings mediated by Reiki.
Materials and methods: Convergent care research, underpinned by Watson's Theory on Human Care, developed in a health facility for people with sickle cell disease in the state of Bahia, Brazil. The study was carried out from August to October 2016. Interviews with participants took place before and after six sessions of transpersonal care mediated by Reiki with seven family members. Thematic content analysis was applied to the data collected.
Results: Participants realized the importance of cultivating self-recognition, identifying their fears and feelings, valuing self-care, reflecting on their health priorities and needs, and recognizing their potential for transforming their practices. After the meetings, feelings emerged towards valuing the self as a person to be cared for, reducing anxiety and stress, reconnecting with beliefs and deities, acceptance of the disease, the role of caregiver and the future, as well as better interaction with family members in order to manage conflicts harmonically.
Conclusions: Transpersonal care favors nursing professionals’ autonomy to create their own way of thinking and practicing longitudinal care, which can be applied throughout the process of prevention, diagnosis and rehabilitation of the disease to achieve healing. It is up to these professionals to deepen theoretically on this approach and use the Clinical Caritas Process in the systematization of nursing care.
Taxonomy, distribution, and conservation status of Geonoma (Arecaceae, Arecoideae): new records for the Maranhão state, Brazil
Authors: Lima Gustavo Pereira , Ferreira Alessandro  Wagner Coelho , De Almeida Jr. Eduardo Bezerra
Published: November 2022

Geonoma is one of the more diverse genera of palms in the neotropical region, which comprises 68 species distributed from southern Mexico to south-western Brazil. In Maranhão, a Brazilian state located in a transition area between the Eastern Amazon, the Cerrado, and the Caatinga, the knowledge about this genus still is deficient. For this reason, we elaborated a taxonomic study of the genus Geonoma for the state, based on the descriptive analysis of voucher specimens of national and international herbaria, and specimens collected in our expeditions. A total of five species were identified: G. baculifera and G. leptospadix species were previously cited in the literature, whereas G. maxima subsp. maxima, G. pohliana subsp. weddelliana and G. poiteauana are presented as new records. Taxonomic descriptions and distribution information are shared, as well as preliminary conservation status assessments of these species. Moreover, an identification key for all species in the state is also supplied. These findings extend the distribution and conservation knowledge of some Geonoma species, and are an important contribution to the identification of the taxa in the region.
Identificación y priorización de especies vegetales nativas para la restauración de playas y dunas erosionadas en Colombia
Authors: Dussan-Arquez Margarita Rosa , Rodríguez-Rodríguez Jenny Alexandra
Published: November 2022

En Colombia las playas y dunas registran problemas de erosión y requieren medidas de restauración. Algunas alternativas plantean incorporar vegetación como mecanismo para estabilizar la arena y mitigar la problemática; sin embargo, no hay lineamientos que permitan avanzar en su uso. Con el objetivo de proveer insumos para desarrollar estas estrategias, se realizó una evaluación de plantas nativas potenciales para la restauración de playas y dunas, analizando sus rasgos de historia de vida. Para ello, mediante revisión de información secundaria, se evaluaron 25 especies nativas a partir de once rasgos, expresados en 25 estados, a los que se les asignó un puntaje de acuerdo con su rendimiento frente a los retos ecológicos a los que se enfrentan. Tras la calificación, seis especies se priorizaron para su investigación y uso en la restauración: Canavalia rosea, Ipomoea pes-caprae, Sesuvium portulacastrum, Batis maritima, Sporobolus virginicus y Spartina spartinae; otras ocho especies se identificaron con potencial. Esta investigación brinda insumos para el diseño de comunidades con mayores probabilidades de éxito en programas de restauración de zonas afectadas por erosión costera en Colombia y abre un abanico de necesidades de investigación en este campo.
Amazonian indigenous territories as reservoirs of biodiversity: The army ants of Santa Sofia (Amazonas – Colombia)
Authors: Sanabria Catalina , Achury Rafael
Published: November 2022

The Amazon basin is undergoing processes of global change that threaten one of the planet’s greatest sources of biological and cultural richness. Among different conservation strategies, indigenous reserves play a key role by reducing the impact of factors such as the deforestation caused by the expansion of the agricultural frontier. Despite the demonstrated importance of these indigenous territories, there is a lack of studies evaluating their contribution to the regional diversity in Colombia, especially for invertebrate groups. By surveying indigenous territories for the first time in the Amazonas department, we investigated the army ant fauna inhabiting different land use types: forests; “chagras” in different stages of regeneration; and pastures. In a sampling plot that represents just 0.0014 % of the department’s area, four genera and eight army ants species were recorded, representing 47 % of known species in the Amazonas department and 18 % in Colombia. Our sampling revealed three new records for the department and Neivamyrmex diana as a new record for the country. Mature forests harbored six species, while the chagras system retained up to five species. Notably, when placing our results in a national context, we revealed several country regions and departments (e.g., Córdoba, Sucre, Vaupés) that presented limited or no information on army ant diversity. Our results provide justification for the continuous evaluation, monitoring and conservation of indigenous reserves, based not only on their demonstrated cultural and ancestral importance but to their potential to retain high biodiversity.
Leaf phenotypic variation in natural populations of Quillaja saponaria and its relationship with climatic variation
Authors: Magni Carlos , Espinoza Sergio , Poch Paola , Abarca Betsabé , Grez Iván , Martínez Eduardo , Vaswani Suraj , Toro Nicole , Gómez Persy
Published: November 2022

Quillaja saponaria is a sclerophyllus evergreen tree species distributed from 30° to 38° S in Central Chile. In this wide distribution it is expected that the species exhibits phenotypic plasticity in the morphology of leaves associated to climate variation; however, the information on this topic is still scarce. We studied leaf phenotypic variation and its relationship with temperature, precipitation, and aridity in 85 stands of Q. saponaria throughout the natural distribution of the species. The results show that the basal diameter of petiole, the number of secondary veins, and the basal diameter of the principal vein increased with precipitation and decreased with aridity, while the length, basal diameter and the relative length of the petiole decreased with temperature. This confirms that phenotypic variation for foliar characters in Q. saponaria is related to climatic variables indicating an adapting capability of the species to the wide range of environmental conditions in which grows.