bluuebunny/crossref_metadata_2025 huggingface dataset:
Brake Strategy Analysis for Industrial Normal-closed Brake Based on Rotational Inertia Test and Simulation
Authors: Sun Yuantao , Chen Kaige , Zhang Qing , Qin Xianrong , Zhang Jianjie
Published: July 2019

Industrial brakes pose the dilemma of weighing brake capability against brake impact since the brake torque cannot be adjusted. On the one hand, the brake torque may be insufficient to stop the movement within a limited distance or parking position. On the other hand, the brake torque may be so high it can damage the transmission chain. In this study, the traditional brake strategy and the field oriented control (FOC) brake strategy were compared through simulation and a rotational inertia test. The influence of the rated brake torque and the open-closed ratio were obtained. Based on the test and simulation results, a semi-empirical formula that defines the relationship between relative brake capability and open-closed ratio was developed. Additional simulations were performed to analyze the performance of the brake in a flexible transmission chain. As an industrial application example, the benefits and the cost of a 'smart brake' based on the FOC brake strategy were analyzed. The results indicate that the equivalent brake torque with the FOC brake strategy is a function of the real-time controllable input and open-closed ratio, which can be conducted during the braking procedure. This can be an efficient way to solve the above problems.
A oralidade incorporada à narrativa contemporânea de Moçambique
Authors: De Brito Daniela
Published: July 2019

Atentando para o entrelaçamento de procedimentos orais e escritos, este artigo tem por objetivo percorrer duas manifestações ficcionais da literatura moçambicana contemporânea, os romances O sétimo juramento (2000), de Paulina Chiziane, e Neighbours (2004), de Lília Momplé,  privilegiando a análise do modo como a performance dos contadores de história é encenada e qual a funcionalidade dessa representação, seja estabelecendo uma comparação entre elas, seja em uma perspectiva individualizada. Lembrando que o corpus escolhido, embora apresente muitas semelhanças, uma vez que todo trabalho que visa aproximar romances de autores diferentes tende a partir de um ponto comum, contém especificidades que serão levadas em consideração.
Da literatura: ensaio, performance e fracasso
Authors: Campiolo Trevizan Suelen Ariane
Published: July 2019

Neste ensaio, a crítica critica a si mesma, assume-se como metacrítica. Quando o ditador, personagem conceitual de Maurice Blanchot, exige que o crítico explicite qual é sua importância na contemporaneidade, este se retira para primeiro esclarecer a própria concepção de literatura. Nessa investigação, passa por pensadores da negatividade, como o já citado Blanchot, além de Michel Foucault, Gilles Deleuze e outros, até chegar a Juliano Garcia Pessanha, autor brasileiro que herda e reelabora tal tradição. Contaminada pelo tom satírico de Luciano de Samósata, proponho um entendimento de literatura como ensaio e performance. O crítico, por fim, compreende o teor artístico e o gesto político da atuação dele.
Enunciação e sentidos: implicações para a revisão de textos
Authors: Trotta Sant'Ana Rivânia Maria
Published: July 2019

Resumo: Entendo a revisão de textos como uma prática que se constitui, basicamente, a partir de uma atividade de interpretação. Como tal, a revisão de textos demanda atenção aos sentidos, que se movem à medida que fazemos intervenções no texto original. Toda alteração implica uma mudança, mesmo que sutil, de sentidos. Curiosamente, não é muito comum encontrar reflexões acerca das implicações semânticas da prática de revisão de textos. Tomando a interpretação como constitutiva da prática de revisão, pretendo refletir, numa perspectiva enunciativa, sobre aspectos enunciativos resultantes de intervenções realizadas em um texto. Para isso, assumo como perspectiva teórica a Semântica da Enunciação, desenvolvida por Eduardo Guimarães, e utilizo alguns conceitos da Análise do Discurso de orientação pecheutiana. Tomo como corpus para análise intervenções de um revisor/editor em um artigo de minha autoria.
O Hipupiára e a poética: uma reflexão sobre os limites do verossímil e da autópsia no século XVI
Authors: Moreira Marcello , Correia Manoela Freire
Published: July 2019

Resumo: O estudo tem como matéria práticas de descrição e, também, uma imagem manuscrita, e outra, análoga, impressa, que compõem livros de Pero de Magalhães de Gandavo, intitulado, o primeiro - manuscrito depositado nos dias de hoje no Museu do Escorial -, Historia da prouincia Sancta Cruz, a que ulgar mente chamamos Brasil: feita por Pero Magalhães de Gandauo, dirigida ao muito Illustre Sñor Do Lionis Pereira, e, o segundo, Historia da prouincia Sãcta Cruz a que ulgarmente chamamos Brasil feita por Pero de Magalhães de Gandauo dirigida ao mui Illusmo Dom Lionis Pa gouernador que foy de Malaca e das demais partes do Sul da India - encontrado no acervo da Biblioteca Nacional do Rio de Janeiro. Objetiva-se compreender como a figuração do monstro Hipupiára, presente nas duas versões do livro de Pero de Magalhães de Gandavo acima mencionados, é constituída poética e retoricamente, evidenciando-se processos de analogia, fundamentais para a composição dos corpora monstrorum, e a relação entre história, poética, autópsia e verossimilhança.
Princípios editoriais ou censura prévia: dialogismo e ideologia nas regras de utilização de redes sociais do Grupo Globo
Authors: Chiodelli Chaise Maria Joana , De Freitas Ernani Cesar , Valério Patrícia Da Silva
Published: July 2019

A base do princípio dialógico bakhtiniano é a filosofia do diálogo e da relação social. E é nessas relações que o indivíduo não apenas se constituiu, mas também se altera, na convivência com outros e a partir da produção de enunciados, impregnados de significados e valores. Partindo de uma perspectiva discursiva, este artigo mobiliza os conceitos de dialogismo e enunciação (BAKHTIN, 2010, 2014) e ideologia (BAKHTIN, 2010) para analisar os princípios editoriais do Grupo Globo que pretendem orientar os jornalistas que atuam nos veículos do grupo sobre como devem proceder diante das redes sociais. O estudo caracteriza-se como exploratório, com cunho bibliográfico, mediante a análise de discurso. As categorias teóricas que fundamentam a análise são extraídas da teoria estudada: atitude responsiva ativa, autoria e acentuação valorativa. A análise empreendida autoriza a dizer que as diretrizes sobre o uso de redes sociais do Grupo Globo restringem a palavra e produzem o que se pode chamar de silenciamento de vozes destoantes dentre os profissionais, e que o enunciado é endereçado muito mais à opinião pública e ao mercado que aos colaboradores, necessariamente.
Pharmacoeconomical Impacts of Crohn’s Disease
Authors: Rudan Stjepan , Gmajnić Rudika , Pribić Sanda
Published: July 2019

Provide an overviewof Crohn’s disease and its cost assessment options, establish the need for implementing Croatian national Crohn’s Disease Registry to precisely quantify the costs and the outcomes, and establish model to evaluate values of treatment options for Crohn’s disease.
Vplyv plyometrického tréningu na zmeny silových schopností vrcholových volejbalistiek
Authors: Vanderka Marián , Kojnok Martin , Longová Katarína
Published: July 2019

The aim two groups time parallel 6-week experiment was to compare selected types of plyometric training. One group trained with gradation of external weight loading in eccentric phase (EXP1) and the second group increased drop height (EXP2) during drop jump training. We compared their effects on changes in selected strength abilities. We assessed the level of countermovement vertical jump height (CMJ), standing vertical jump height (SJ) and average force gradient in squat exercises with the knee joint in 90 ° by maximal isometric contraction at intervals of 0-50 ms (RFD50) and 0-200 ms (RFD200). The results showed that in CMJ EXP1 had improved by 1.01 cm (3.5%) (p<0.01). EXP2 improved by an average of 1.78 cm (5.5 %) (p<0.05). SJ in EXP1 average improved by 0.94 cm (3.5 %) (p = n.s.) in EXP2 by 1.91 cm (6.6 %) (p<0.05). In RDF50 the average increase observed after a period of training in EXP1 1.03 N.ms-1 (26.08 %) (p = n.s.) and EXP2 0.57 N.ms-1 (16.39 %) (p<0.05). In the EXP1 RFD200 the average increase was 2.51 N.ms-1 after a period of training (20.91 %) (p<0.01), while on average EXP2 improved by 1.05 N.ms-1 (10.04 %) (p = n.s.). Based on these results we recommend to improving of vertical jump height with a countermovement and force gradient in longer intervals (200 ms) to apply the external weight in the form of small dumbbells in eccentric phase of drop jump training. To standing jump height development and shorter time intervals of force gradient (50 ms) is recommended to use a gradual increase in height of drop in plyometric training.
Leachate tertiary treatment using wetlands cultivated with oilseeds
Authors: Florênço João Antônio Monteiro , Scherolt Lucas Zanon , Trevisan Viviane , Skoronski Everton
Published: July 2019

The objective of this study was to evaluate the efficiency of the wetlands cultivated with sunflower and soybean in the removal of Chemical Oxygen Demand, ammonia, nitrate, nitrite, total phosphorus and Kjeldahl Total Nitrogen (KTN) of the treated leachate from the landfill treatment plant of the city of Lages / SC. It was also analyzed the plants development as a function of the effluent applied in the wetlands compared to wetlands irrigated with chemical fertilizer. The wetlands were operated in batch with hydraulic retention times (HRT) of 2 and 4 days, receiving treated slurry in concentrations of 10 and 25% and liquid chemical fertilizer (5 ml / L). In the tests carried out with HRT of 4 days only the concentrations of COD and of ammonia were analyzed. After 4 months, the plants size was measured to verify their growth. In the tests carried out with the soybean there was no germination of the seeds. In both HRT tested, a greater removal of phosphorus, ammonia, nitrite and KTN was observed when 25% concentration of leachate. It was observed that the sunflower plants showed a higher size when cultivated in wetlands operated with HRT of 4 days and that they received the treated leachate in the concentration of 10%.
Removal of textile dye Remazol Brilliant Blue Reactive (RBBR) using fibers of Citrullus lanatus (watermelon) and Cocos nucifera (green coconut) as adsorbent material
Authors: Krueger Melissa Dominique de Sousa , Volkmann Ana Carolina , Rainert Karine Thaise
Published: July 2019

The accumulation of agro-industrial waste causes major environmental problems since most of these wastes are disposed of improperly. Among them, there are the watermelon (Citrullus lanatus) and the green coconut (Cocos nucifera), fruits of resistant and fibrous peels which are discarded in landfills because they are not widely used. Thus, the adsorption capacity of the Remazol Brilliant Blue Reactive (RBBR) dye was investigated using green coconut and watermelon residues as adsorbents. The combined effects of two independent variables (pH and adsorbent mass) were evaluated using the response surface methodology. Under optimal conditions of acid pH and adsorbent mass of 1 g, the dye removal efficiency reached values above 80% for both residues. The adsorption kinetics was described by the pseudo-second order model, while the equilibrium study was represented by the Freundlich isotherm for the watermelon residue and the Langmuir model for the green coconut. The results show that the agroindustrial residues of watermelon and green coconut could be effectively used to remove dye remazol brilliant blue reactive.
Contributions to reduce the flood problems in critical points of the micro drainage system in the city of Carazinho
Authors: Koppe Carolina Pasquetti , Scortegagna Vinícius , Meneguzzi Virgínia , Gil Anelise Sertoli Lopes , Ferreira Matheus De Conto , Fiori Simone , Fernandes Vera Maria Cartana
Published: July 2019

With the emergence of excessive flooding in the urban environment, the need for unconventional drainage control measures within the limitations of conventional solutions becomes evident. In the present study, infiltration trenches and reservoirs that collect and reserve rainwater were designed as control devices, attenuating the socio-environmental impacts caused by waterproofing of urban areas in the hydrological cycle and in the behavior of the hydrographic basins in question. The measurements were made for two flooding points found in the city of Carazinho – RS, located on Marquês do Pombal Street and São Bento Avenue, due to the obstruction of gutters and street inlets, paving and waterproofing of the ground due to urbanization, lack of maintenance and cleaning of the micro drainage system along with the inability of the system to collect all the volume of water from the runoff. The reductions in flow rate in these areas through the use of trenches were 16% and 15% for the first and second flooding point, respectively, while the use of the delay reservoirs together with the infiltration trenches resulted in a 29% reduction in the first flooding point and 27.5% in the second flooding point. Therefore, it is evident that the use of unconventional control measures is vital to the reduction of the peaks of the flow rate and control of the surface runoff.
Production and evaluation of particleboard made of sawdust and sugarcane bagasse with polyurethane resin based on castor oil
Authors: Pivetta Raissa Pravatta , Buzo Ana Laura Soler Cunha , Sugahara Estéfani Suana , Silva Sérgio Augusto de Mello da
Published: July 2019

Among the goals for sustainable development in Brazil, studies have been conducted to better use of industrial and agricultural waste to promote adequate final disposal of these and generate new materials that minimize the exploitation and use of natural resources. In this work, the proposal is to make and evaluate boards with nominal density of 0.80 g.cm-3 using sugar cane bagasse, sawdust and polyurethane resin derived from castor oil. Thus, three treatments with different percentages of particles and 10% of PU-castor were proposed for the preparation of boards that were pressed with a pressure of 50 kgf.cm-2, a temperature of 100°C and a pressing time of ten minutes. The boards were evaluated for their physical properties (density, moisture content and swelling) and mechanical (static flexure and perpendicular traction) according to NBR 14810: 2-2013 and presented average values density of 936 to 937 kg.m-3, swelling after 24 hours of 5.0 to 7.2%, modulus of resistance to static bending of 22 to 23 MPa and perpendicular traction of 0.71 to 0.87 MPa. The results obtained with the tests indicate the great potential of use of sugarcane bagasse and sawdust to produce boards of high density particles.
Measures for reduction of the water losses in the distribution network: a case study on the municipality of Altônia/PR
Authors: Gorzoni Vitor Alécio Sevilha , Pereira Priscila Pini , Lautenschlager Sandro Rogerio , Okawa Cristhiane Michiko Passos
Published: July 2019

The water losses management provides cost reduction for sanitation companies and, thus, for the treated and distributed water’s final users. In the face of the recent episodes of hydric crisis in the state of São Paulo, it is essential to have a good water supply management system, which includes controlling the water loss volume in the system. The easiest way to manage this control is based on the water balance, in other words, calculating the difference between the distributed volume and the volume measured in the consumption units. This work presents one case study at the municipality of Altônia, in Paraná, where the continuous expansion of the water supply system has led to the increase of the water loss volume on the distribution process. The municipality has chosen procedures as the appropriate and periodic maintenance of the network, installation of new water meters and pressure reduction valves and the monitoring of leakages with mechanical tools. Thus, it was possible to reduce the water loss volume by half.
Upflow anaerobic sludge blanket reactor and biofilter in polyethylene as an alternative of decentralized wastewater treatment in municipality of Rio Rufino – SC
Authors: Souza Diego Hoefling , Schroeder Aline , Skoronski Everton
Published: July 2019

Basic sanitation services are essential for promoting public health and for mitigating environmental damage. Thus, the objective of this work was to evaluate a wastewater treatment system consisting of anaerobic sludge blanket reactor and biofilter, as an alternative for the decentralized wastewater treatment in the municipality of Rio Rufino - Santa Catarina. The system was evaluated for its efficiency of removal of fecal coliforms, biochemical oxygen demand, chemical oxygen demand, soluble chemical oxygen demand, phosphorus, Total Kjhedal Nitrogen, nitrite, nitrate, sedimentable solids and maintenance of the hydrogen potential in the effluent. The treated effluent had its parameters compared to the standards established by Resolution 430/2011 of the Conselho Nacional do Meio Ambiente and Law 14.675 / 2009 of the State of Santa Catarina. It was also performed the estimate of the daily biochemical oxygen demand load, originated by the population of the municipality, and its respective impact. The effluent treated by the proposed system, when properly installed, follows what was established by the legislation, which implies in reducing the impacts caused by the municipality. In this way, the system can be an interesting alternative when it comes to decentralized wastewater treatment.
Analysis of estuarine flood levels based on numerical modelling. The Douro river estuary case study
Authors: Venâncio Stênio De Sousa , Pinho José Luís , Vieira José Manuel , Avilez-Valente Paulo , Iglesias Isabel
Published: July 2019

Estuarine hydrodynamics present intermittent and complex circulation patterns. In this context, from the point of view of the coastal management associated with flood risks in riverine areas, numerical models allow predicting scenarios under specific hypotheses. This work simulates flood events occurring in the Douro river estuary recurring to numerical modelling tools. This estuary, located in the northern region of Portugal, periodically suffered severe flooding, with the associated losses and damages for the local protected landscape areas and hydraulic structures. The occurrence of these events justify the importance of a complete characterization of the areas that present risk of inundation and how they can be affected. A 2D-horizontal numerical model implemented with the Delft3D software was developed for this estuarine region including also the adjacent coastal zone. Available in-situ data were used for model calibration and validation processes. The obtained results are consistent with the in-situ measured water levels, allowing to understand the dynamics of the estuary during flood events. The robustness of the implemented numerical model allows to anticipate flood scenarios effects and associated water levels. The simulations results can then be used for sustainable management of this estuarine zone that presents high social, economic and environmental values.
Natural characterization of the low course of the Camaquã River in Cristal city-RS
Authors: Beier Elissandro Voigt , Poleto Cristiano , Ferreira Maria Eugênia Moreira Costa
Published: July 2019

A portion of the rural territory of the Cristal City-RS was analyzed in order to assess the natural characteristics such as pedology, geology, geomorphology, water network, climatology and the biogeography of this geographical area. For the survey, bibliographical sources such as topographic charts, survey maps of IBGE, reference sources like phytogeographic surveys, and detailed studies of sedimentary and hydrological dynamics that transformed the region in the past were considered. From this study, specific characteristics for each of the analysis categories were mapped in definite charts and analyzed in their context of occurrence. As a result, it was possible to characterizate the natural conditions of the region whose current scenario presents significant differentiation by the anthropic interference in the environment.
La educación musical y el comparatismo
Authors: Esteve Faubel José María
Published: July 2019

Music education is one of the most recent subjects to be included in the respective school curricula of Spain’s compulsory education system —infant, primary and secondary— and it is where praxis finds its raison d’être. The problem lies in understanding what is involved in this procedure —praxis— as well as knowing the difficulties arising from its application. To this end, it is necessary to answer complex questions related to defining music and music education, as well as understanding the importance of relating music education to comparative education as a means by which to conduct valuable research in this subject.
Editorial: Comparatística y Metodología
Authors: Aullón de Haro Pedro
Published: July 2019

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La reconciliación entre la historia y la comparación
Authors: Schriewer Jürgen
Published: July 2019

Since its definition as a method considered as ‘scientific’, towards the end of the 19th century, the comparative method in the social sciences has relied on the principle of causality. In shaping this conception of comparative methodology, the example of the natural sciences and the impact of the orthodox philosophy of science have always been crucial. However, in contrast to scientistic assumptions of this kind, this article refers to far-reaching paradigm shifts and theoretical reorientations that are associated with the emergence of interdisciplinary theory programs on 'self-organization', 'autopoiesis' and 'complex causality'. The article is aimed, then, at delineating an alternative approach to comparative analysis, i.e. an approch that promises to take more adequately into account the complex causal relationships that are characteristic of macrosocial configurations, as well as the irrevocably historical nature of the social world.
Exports, Terms of Trade and Economic Growth: Evidence from Countries with Different Level of Openness
Authors: DabÃºs Carlos , Delbianco Fernando
Published: July 2019

This paper explores the effects of the ratio exports/GDP and the terms of trade on growth among countries with different level of development and openness. These effects vary among subgroups of countries with different openness and per development level. Nonetheless, in general the evidence seems to support the hypothesis stated in this research. In less developed or better endowed for export countries one or both of the explanatory variables mentioned above encourage for economic growth. Specifically, in advanced economies only the ratio exports/GDP is growth promoting when these are open, and have high per capita but small global GDP and/or relative advantages to be growth export-led. In turn, exports or and the terms of trade trends to promote growth in lower middle income countries. Unfortunately, the surprising results came from the poorest countries. They do not are benefited from a more favourable foreign environment. On the contrary, exports are not significant while an improvement in the terms of trade diminishes their growth.
Análise descritiva de parâmetros meteorológicos como auxílio no cultivo de mamona em Diamantino/MT
Authors: Lima Luis Philippe Arruda , Gama Kamyla Fernanda Silva , Rosa Lauro Leocadio , Garcia Silvino Mendes , Musis Carlo Ralph de , Gaio Denilton Carlos
Published: July 2019

A mamona vem se destacando como alternativa de cultivo entressafras em várias partes do Brasil devido, principalmente, a sua utilização como matéria prima de biodiesel. Mais fortemente produzida no Nordeste Brasileiro, essa cultura possui características as quais a fazem adaptar em diferentes lugares do país tupiniquim. Cidade em que se destaca fortemente nos cenários agrícolas estadual e nacional, Diamantino, presente na região da Chapada dos Parecis em Mato Grosso, é uma das principais cidades produtoras de grãos de soja no Brasil. Além da soja, a cidade também desponta como grande produtora de algodão e milho. Juntamente com o crescimento da produção agrícola, de uma maneira geral, ampliam-se os estudos de monitoramento e de descrição dos parâmetros meteorológicos importantes para o desenvolvimento dessas culturas, que servem também como auxílios para introdução de culturas não oriundas da região. Ante o exposto, este trabalho teve como objetivo avaliar, em relação à recomendação da literatura, às condições dos parâmetros meteorológicos para práticas de cultivares de mamoneira na cidade de Diamantino/MT. Para isso, realizou-se análise descritiva dos dados de temperatura do ar, precipitação e umidade relativa do ar referentes ao período de 2006 a 2015, obtidos juntos ao INMET. Obteve-se o período entre abril e setembro como o mais adequado para o cultivo de mamona na cidade, sendo os cultivares com ciclos mais curtos os mais apropriados. Os cultivares com longos ciclos, de até 250 dias, podem sofrer influência negativa dos excessos de chuva e umidade relativa.
Análise da adequabilidade de indicadores de erodibilidade de solos baseados em parâmetros geotécnicos
Authors: Santos Ramon Eduardo Salles dos , Araujo Rodrigo da Cruz de
Published: July 2019

Os processos erosivos são capazes de causar mudanças no cenário em que atuam, causando prejuízos materiais e fatalidades. Esse estudo tem papel importante, pois pode auxiliar na previsão do comportamento do solo, e mapeamento das áreas de risco com maior precisão, evitando que pessoas se estabeleçam nessas áreas. Uma voçoroca foi selecionada na Avenida Litorânea, São Luís (MA). Três amostras foram colhidas em diferentes níveis (0m, 1.5m, 3m) para realização de ensaios de granulometria, teor de umidade, limite de liquidez e limite de plasticidade. A literatura apresenta propostas que relacionam os índices físicos do solo e a susceptibilidade do mesmo a sofrer erosão. Fazendo essa correlação, os resultados encontrados apontam que alguns critérios previram bem o comportamento do solo enquanto outros fizeram previsões incorretas. Pela ausência de um banco de dados amplo, e pela análise de adequabilidade ainda estar acontecendo, fazer uso desses métodos requer muito cuidado.
O desempenho das nações em desenvolvimento sustentável: uma análise de conglomerados no environmental performance index
Authors: Gomes Roberta Pacheco , Machado Diego de Queiroz , Moreira Márcia Zabdiele , Araújo Carlos Manta Pinto de
Published: July 2019

Diante da crescente importância conferida aos indicadores de desenvolvimento sustentável e visando a contribuir para a agenda de estudos em desenvolvimento sustentável, o presente trabalho tem como objetivo geral analisar o nível atual de desempenho em desenvolvimento sustentável das nações ao redor do mundo com base nos indicadores que compõem o Environmental Performance Index - EPI. Para tanto, são apresentados, no referencial teórico, a origem, o conceito e as dimensões do desenvolvimento sustentável; a concepção e os principais indicadores de desenvolvimento sustentável; e, por fim, o próprio EPI. Quanto à metodologia, utilizou-se a base de dados do EPI 2014 e aplicou-se o método quantitativo de análise de conglomerados à amostra de 104 dos 178 países que compõem o índice, visto que apenas foram considerados na separação dos grupos aqueles com dados para todas as variáveis utilizadas. Conclui-se, a partir da criação de quatro diferentes grupos de países pela análise de conglomerados, os diferentes níveis de desempenho geral em desenvolvimento sustentável em que se encontram as nações analisadas, além de características dos países que definem o seu desempenho. Por fim, foi possível observar, em cada um dos grupos formados, pontos críticos de avanço em políticas públicas em prol do desenvolvimento sustentável destas nações.
Conn’s Syndrome Akibat Adenoma Adrenal
Authors: Rasyid Haerani , Bakri Syakib , Kasim Hasyim , Hidayat Andi Rahmat , Syarif Syarif , Azis Abd
Published: July 2019

Conn’s syndrome merupakan sindrom yang ditandai dengan peningkatan kadar aldosteron yang menyebabkan retensi natrium dan peningkatan ekskresi kalium melalui urin. Sindrom ini ditandai dengan trias hipokalemia, hipertensi, dan alkalosis metabolik. Artikel ini membahas mengenai laporan kasus pasien hipertensi tidak terkontrol dengan gejala neuromuskular yang diakibatkan oleh hipokalemia berulang. Setelah dilakukan evaluasi tes pencitraan, ditemukan gambaran tumor adrenal kiri dan kemudian dilakukan tindakan adrenalektomi unilateral. Hasil pemeriksaan histopatologi tumor didapatkan gambaran yang sesuai dengan adenoma adrenal. Setelah tindakan adrenalektomi unilateral, pasien menunjukkan perbaikan klinis dan laboratorium. Kata kunci : Conn’s syndrome, Hipertensi, HipokalemiaConn’s Syndrome Due to Adrenal AdenomaConn's syndrome is characterized by an increase in aldosterone level causes sodium retention and an increase in urine excretion of potassium. This syndrome is characterized by trias hypokalemia, hypertension, and metabolic alkalosis. This article discussed a case report of a patient with uncontrolled hypertension with neuromuscular symptoms caused by recurrent hypokalemia. After an evaluation of the imaging test, we found a left adrenal tumor then we performed unilateral adrenalectomy surgery. Histopathology examination from the excised tumor revealed the adrenal adenoma. After unilateral adrenalectomy, the patient showed clinical and laboratory improvement.
The Solitary Blue Toe: A Unique Presentation of Antiphospholipid Syndrome
Authors: Dimond Devin G. , Lam Jenny K. , Wurster Lauren , Kiser Christopher , Driscoll Kevin , Razzante Mark
Published: July 2019

Antiphospholipid syndrome is an autoimmune disease characterized by vascular thrombosis involving both the arterial and venous systems that can lead to tissue ischemia or end-organ damage. Much of the literature describes various symptoms at initial presentation, but isolated tissue ischemia manifesting as a solitary blue toe is unusual. We discuss a case of a 23-year-old man who presented to the emergency department with a solitary blue fourth digit with minimal erythema and edema, who was suffering from exquisite pain. Following an extensive workup, the patient was diagnosed with antiphospholipid syndrome with thrombi of the vasculature in their lower extremity. With therapeutic anticoagulation, the patient's symptoms subsided and amputation of the digit was prevented.
A composition-dependent molecular clutch between T cell signaling condensates and actin
Authors: Ditlev Jonathon A , Vega Anthony R , Köster Darius Vasco , Su Xiaolei , Tani Tomomi , Lakoduk Ashley M , Vale Ronald D , Mayor Satyajit , Jaqaman Khuloud , Rosen Michael K
Published: July 2019

During T cell activation, biomolecular condensates form at the immunological synapse (IS) through multivalency-driven phase separation of LAT, Grb2, Sos1, SLP-76, Nck, and WASP. These condensates move radially at the IS, traversing successive radially-oriented and concentric actin networks. To understand this movement, we biochemically reconstituted LAT condensates with actomyosin filaments. We found that basic regions of Nck and N-WASP/WASP promote association and co-movement of LAT condensates with actin, indicating conversion of weak individual affinities to high collective affinity upon phase separation. Condensates lacking these components were propelled differently, without strong actin adhesion. In cells, LAT condensates lost Nck as radial actin transitioned to the concentric network, and engineered condensates constitutively binding actin moved aberrantly. Our data show that Nck and WASP form a clutch between LAT condensates and actin in vitro and suggest that compositional changes may enable condensate movement by distinct actin networks in different regions of the IS.
Inter-individual differences in human brain structure and morphology link to variation in demographics and behavior
Authors: Llera Alberto , Wolfers Thomas , Mulders Peter , Beckmann Christian F
Published: July 2019

We perform a comprehensive integrative analysis of multiple structural MR-based brain features and find for the first-time strong evidence relating inter-individual brain structural variations to a wide range of demographic and behavioral variates across a large cohort of young healthy human volunteers. Our analyses reveal that a robust ‘positive-negative’ spectrum of behavioral and demographic variates, recently associated to covariation in brain function, can already be identified using only structural features, highlighting the importance of careful integration of structural features in any analysis of inter-individual differences in functional connectivity and downstream associations with behavioral/demographic variates.
Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice
Authors: Zhang Hongsheng , Sathyamurthy Anupama , Liu Fang , Li Lei , Zhang Lei , Dong Zhaoqi , Cui Wanpeng , Sun Xiangdong , Zhao Kai , Wang Hongsheng , Ho Hsin-Yi Henry , Xiong Wen-Cheng , Mei Lin
Published: July 2019

Adult neurogenesis in the hippocampus may represent a form of plasticity in brain functions including mood, learning and memory. However, mechanisms underlying neural stem/progenitor cells (NSPCs) proliferation are not well understood. We found that Agrin, a factor critical for neuromuscular junction formation, is elevated in the hippocampus of mice that are stimulated by enriched environment (EE). Genetic deletion of the Agrn gene in excitatory neurons decreases NSPCs proliferation and increases depressive-like behavior. Low-density lipoprotein receptor-related protein 4 (Lrp4), a receptor for Agrin, is expressed in hippocampal NSPCs and its mutation blocked basal as well as EE-induced NSPCs proliferation and maturation of newborn neurons. Finally, we show that Lrp4 interacts with and activates receptor tyrosine kinase-like orphan receptor 2 (Ror2); and Ror2 mutation impairs NSPCs proliferation. Together, these observations identify a role of Agrin-Lrp4-Ror2 signaling for adult neurogenesis, uncovering previously unexpected functions of Agrin and Lrp4 in the brain.
The hippocampus supports deliberation during value-based decisions
Authors: Bakkour Akram , Palombo Daniela J , Zylberberg Ariel , Kang Yul HR , Reid Allison , Verfaellie Mieke , Shadlen Michael N , Shohamy Daphna
Published: July 2019

Choosing between two items involves deliberation and comparison of the features of each item and its value. Such decisions take more time when choosing between options of similar value, possibly because these decisions require more evidence, but the mechanisms involved are not clear. We propose that the hippocampus supports deliberation about value, given its well-known role in prospection and relational cognition. We assessed the role of the hippocampus in deliberation in two experiments. First, using fMRI in healthy participants, we found that BOLD activity in the hippocampus increased as a function of deliberation time. Second, we found that patients with hippocampal damage exhibited more stochastic choices and longer reaction times than controls, possibly due to their failure to construct value-based or internal evidence during deliberation. Both sets of results were stronger in value-based decisions compared to perceptual decisions.
Nanocomposite Polymer Adhesives: A Critical Review
Authors: Kenig S. , Dodiuk H. , Otorgust G. , Gomid S.
Published: July 2019

With recent developments in nanotechnology, nanocomposite adhesives offer numerous advantages compared to conventional adhesive materials. Moreover, with the emergence of commercial nanomaterials such as: Nanoclays (NCs), Carbon nanotubes (CNTs), Nanosilica (NS), Polyhedral oligomeric
silsesquioxanes (POSS), Tungsten disulfide (WS2) Fullerenes and Nanotubes, and Graphene nanoparticles (GNPs), new potential routes have been opened to tailor adhesives in the nanoscale range. This update will review and analyze the unique fracture mechanisms and the resultant properties
of various nanocomposite adhesives based on epoxies, polyurethanes, silicones, polyimides and acrylics containing: NCs, CNTs, NS, POSS, WS2 and GNPs and their current and potential applications.
Adhesion Enhancement of Polymer Surfaces by Ion Beam Treatment: A Critical Review
Authors: Srinadhu Endu Sekhar , Shyam Radhey , Kumar Jatinder , Thanu Dinesh P R , Zhao Mingrui , Keswani Manish
Published: July 2019

Polymers are widely used in different types of industries ranging from microelectronics, medical to space applications. However, polymer materials are seldom used in their pristine state and are in need of selective surface treatment to induce a specific response which is a challenging
and complex task. Adhesion enhancement of polymers is one of the major requirements that can be achieved with ion beam technology at low cost. Surface enhancement involves keeping the bulk properties of materials unchanged and modifying only the surface properties to achieve optimum results.

In this review, we illustrate the use of ion beam technology to modify the surface properties of polymers for potential biomedical and microelectronics applications. This review focuses on effects on the adhesion characteristics for different polymer materials of various optimizable parameters
such as type of ion used, ion energy regime (low to medium to high) and the ion fluence range.
Monitoring the critically endangered Clanwilliam cedar with freely available Google Earth imagery
Authors: Slingsby Jasper A. , Slingsby Peter W. O.
Published: July 2019

Monitoring of species and populations is essential for biodiversity observation and reporting at local, national and global scales, but can be an exceedingly difficult task for many, if not most, species. We tested the viability of using Google Earth™ imagery to manually map and monitor all individuals of the critically endangered Clanwilliam cedar, Widdringtonia wallichii Endl. ex Carrière, across its global native distribution; the remote and rugged Cederberg mountains. Comparison with sampling from field surveys reveals this to be a highly efficient and effective method for mapping healthy adult tree localities, but it fails to detect small or unhealthy individuals with green canopies <4 m2, or discern the number of individuals in clumps. This approach is clearly viable as a monitoring tool for this species and, with the rapid progress being made in machine learning approaches and satellite technology, will only become easier and more feasible for a greater number of species in the near future. Sadly, our field surveys revealed that the number of trees that have recently died (dead leaves still present) outnumbered live trees by a ratio of 2:1.
Analysis of Factors Influencing the Price of Paddy Rice in Benue State, Nigeria
Authors: Moses Ogah, Odey , Iveren Tyo, , Abah Abiyoung, Paul
Published: July 2019

The study analyzed the factors influencing the price of paddy rice in Benue State, Nigeria. Data were collected from 113 rice farmers’ marketers using multi-stage sampling technique. Data were analyzed using descriptive statistics and multi-regression model. The study revealed that respondents were in their active age, mostly males (65.5%), married (69.0%) formal education (79.6%), average marketing experience of 9 years and 10 members per household. Quality type of paddy rice, season and transport cost were the important and significant variables that influence the price of paddy rice in the study area. These were significant at 5%, 5% and 1% levels of probability respectively with an R2 value of 0.77. Based on these findings, it is recommended that government should construct new roads and rehabilitate rural feeder roads to ease movement of produce and also provide incentives to women to encourage them in farming. The three tiers of governments should provide adequate transportation system to help in conveying paddy rice from their place of production to the place of consumption.
The Effects of Peer Tutoring on Seventh-grade Students’ Learning in Science
Authors: Ghalley Lekh Raj , Tobgay Sonam , Rai Budhi Man , Penjor Dorji , Oli Govinda , Tenlo Sonam
Published: July 2019

Peer tutoring is a common instructional strategy used in classrooms. This study focused on the effects that peer tutoring has on students of the novice group. The effect of peer tutoring was compared based on the score of pretest and posttest to those of the control group. At the end of the tutoring session, the satisfaction of the students was accessed by administering questionnaires. Hence, this is a mix-mode research where survey questionnaire and class tests score has been used. The questionnaires consist of two parts.  Part one consisted of nine closed questions using a Likert scale and in addition to the opportunity to provide free text comments and part two consists of five close ended questions using a Likert scale to assess the usefulness of the tutoring session. The posttest result showed that 7 out of 8 participants made significant progress after intervention. The student’s perceptions on the action-tutoring strategy were all positive that students were satisfied with tutoring timing, session and had found useful to be recommended with other friends. Hence, it has positive effect in learning science at class seven
Physico-chemical Characterization of Blends Based on Milk and Catole Coconut Pulp
Authors: Matos Joana D’arc P. , Figueirêdo Rossana Maria F. , Silva Luis Paulo F. R. , Moraes Maria Suiane de , Silva Semirames do N. , Costa Zanelli Russeley T. da , Queiroz José Alexandre de M. , Rodrigues Larissa Monique de S. , Vieira Agdylannah F.
Published: July 2019

Aims: Coconut catole is the fruit of the Syagrus cearenses palm tree, whose pulp is usually eaten in its natural form. The formulation of blends is intended to improve the acceptance of fruit with potential to be exploited. The objective of this work was to evaluate the physico-chemical characteristics of the whole coconut pulp and the blends formulated with the pulp and milk.

Place and Duration of Study: The coconut catole (Syagrus cearensis) were collected in the surroundings of location 551'30 "S, 35º21'13 "O, in Rio Grande do Norte. The work was carried out from January to February 2019.

Methodology: The formulations were elaborated by mixing the proportions of 30 and 50% of standardized commercial milk with the whole catole coconut pulp. The products were submitted to the analysis of moisture, water activity (aw), titratable total acidity (TTA), total soluble solids (TSS), TSS/TTA ratio, pH, ascorbic acid, ash, lipids, proteins, color (L*, a*, b*), total sugars, reducers and non-reducers.

Results: From the results, it was observed that the addition of milk to the pulp resulted in clear samples and that a higher proportion of the milk statistically influenced the results.

Conclusion: The mixture of couscous coconut pulp and milk gave the product better nutritional characteristics, especially protein content and lipid reduction. The addition of the milk to the cocoa pulp influenced the results statistically, showing that the addition of the milk contributed to enhance the pulp.
Prevalence and Risk Factors of Sexually Transmitted Infections in Selected Health Facilities in Southwest Region of Cameroon
Authors: Chanyi Livinus , Nkenyi Rene , Esum Mathias
Published: July 2019

Background: Gonorrhoea and Syphilis are common STIs, particularly among the reproductive age group in most developing countries. Their control is important considering the high incidence of acute infections, complications and their socioeconomic impact and a means of effecting control measures against Human Immunodeficiency Virus (HIV).  Knowledge of the prevalence and risk factors of these infections in a student residential area will enable development of better strategies for STI control.

Methods: A health facility based historical study design was conducted where laboratory records of patients screened for Syphilis and/or Gonorrhea and HIV in selected Primary Health Care (PHC) facilities in Buea Health District (BHD) between 2010 and 2015 were reviewed. Data analysis was done using EPI Info version 3.5.4. with a level of error set at 5%.

Results: A total of 1106 records were reviewed. Majority 472(42.7%) were between 21-30 years old, while 923(83.4%) were females. A significant proportion 78 (8.1%) were HIV positive.  The prevalence of the both STIs was highest in 2015. The prevalence of gonorrhoea was 12.9% and that of syphilis was 16.9%. The odds of testing positive for syphilis for female compared to males was 0.33 (95% CI: 0.18-0.62); p-value of 0.001, while that for gonorrhoea was 0.22 (95%CI: 0.11, 0.44); p-value of 0.0001. Patients between 21 and 30 years were 2.46 times as likely to be syphilis positive compared to those below 21. Compared to those tested positive, patients who were negative for were 3.33 (95%CI 1.66-6.69) times as likely to test negative for HIV (p value of 0.001).

Conclusion: The study revealed a high prevalence of gonorrhoea and syphilis. Although these infections have similar risk factors, there are distributed differently in the sexually active student residential area. This thus calls for the implementation of targeted screening and to revise control measures for STIs in the population.
Health Risk Analysis of Heavy Metals (Cr, Fe, Hg & Ni) in Edible Vegetables in Yala Urban Area of Cross River State, Nigeria
Authors: Akomaye Akpe, Michael , Beteluwhobel Ashishie, Providence , Patrick Inezi, Faith
Published: July 2019

Aim: The aim of the study was to determine concentration of heavy metals in the soil and edible vegetables planted consumed Yala Urban Area of Cross River State, Nigeria, ascertained the level of metals contamination and the possible health risk or implication.

Sampling: Forty eight (48) soil and edible vegetable samples (6 of each kind of the 8 vegetables) were collected randomly from Yala Urban Area of Cross River State. The eight vegetables considered for the study were Amaranthus spp., Corchorus olitorius, Murraya koenigii, Ocimum grattissimum, Solanum melongena, Talinum triangulare, Telferia occidentalis and Vernonia amygdalina. They were collected between January and March for dry season, and July and September for rainy season of the year. 

Methodology: The samples were digested and analyzed for the Cr, Fe, Hg and Ni (heavy metals) concentration using Flame Atomic Absorption Spectrometer (AAS) in the Chemistry Laboratory, University of Calabar.

Results: The results showed that the mean concentration of the metals in the soil in mgkg-1 ranged from (0.063 - 0.108) and (0.049 - 0.104) in rainy and dry seasons respectively for Cr, and (0.026 - 0.124) and (0.013 - 0.119) in rainy and dry season respectively for Fe. The mean concentration accumulated by the vegetables ranged from (0.037- 0.063) and (0.029 - 0.066) in rainy and dry season respectively for Cr and (0.012- 0.071) and (0.008- 0.086) in rainy and dry season respectively. Hg and Ni were neither detected in the soil nor in the vegetables. The trend of the metals in both the soil and vegetable was in the order: Cr > Fe> Hg> Ni. The Target Hazard Quotients were all less than 1, indicating no health risk.

Conclusion: These results suggest that there is no significant difference between the amount of metals in the soil or that accumulated by the vegetables in rainy and dry seasons of the year. Also the amount of metals accumulated by most of the vegetables was directly proportional to the amount present in the soil where they are planted. These results indicate that the concentration of Cr, Fe, Hg and Ni in the soil and vegetables were still low and within the permissible limits of WHO/FAO. Thus, the consumption of the vegetables in the area may not pose any risk at the moment.