bluuebunny/crossref_metadata_2025 huggingface dataset:
CTL CD103+ treated TGF-β on rICAM-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Authors: Boutet Marie , Gauthier Ludiane , Leclerc Marine , Gros Gwendoline , de Montpreville Vincent , Théret Nathalie , Donnadieu Emmanuel , Mami-Chouaib Fathia
Published: April 2023

CTL CD103+ treated TGF-β on rICAM-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Supplemental Fig.S.5. from HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy
Authors: Liu Tongzheng , Fang Yuan , Zhang Haoxing , Deng Min , Gao Bowen , Niu Nifang , Yu Jia , Lee SeungBaek , Kim JungJin , Qin Bo , Xie Fang , Evans Debra , Wang Liewei , Lou Wenhui , Lou Zhenkun
Published: April 2023

Representative strong and weak staining of HEATR1 in pancreatic ductal adenocarcinoma.
Supplemental Figure Legends from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

Supplemental Figure Legends
Supplemental Figure 3 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

SCC1-C cells are not sensitized to radiation by cetuximab in vitro and remain susceptible to cetuximab-mediated ADCC.
Supplementary Figure S8 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Supplementary Figure S8. Correlation between mIR-29s expression and catenin-ÃŽ' in 66 cases of GCs.
Supplementary Figure Legends from Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
Authors: Bhola Neil E. , Jansen Valerie M. , Koch James P. , Li Hua , Formisano Luigi , Williams Janice A. , Grandis Jennifer R. , Arteaga Carlos L.
Published: April 2023

Figure Legends for Figures S1-S6
Supplementary Methods and References from Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells
Authors: Mittal Deepak , Caramia Franco , Michiels Stefan , Joensuu Heikki , Kellokumpu-Lehtinen Pirkko-Liisa , Sotiriou Christos , Loi Sherene , Smyth Mark J.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary figure 2 from p73 and IGF1R Regulate Emergence of Aggressive Cancer Stem–like Features via miR-885-5p Control
Authors: Meier Claudia , Hardtstock Philip , Joost Sophie , Alla Vijay , Pützer Brigitte M.
Published: April 2023

Mutual regulation of miR-885-5p by p73/DNp73.
Supplementary Table 4 from Phosphotyrosine Signaling Analysis in Human Tumors Is Confounded by Systemic Ischemia-Driven Artifacts and Intra-Specimen Heterogeneity
Authors: Gajadhar Aaron S. , Johnson Hannah , Slebos Robbert J.C. , Shaddox Kent , Wiles Kerry , Washington Mary Kay , Herline Alan J. , Levine Douglas A. , Liebler Daniel C. , White Forest M.
Published: April 2023

Supplementary Table 4. Summary of colon tumor iTRAQ LC-MS/MS pTyr analysis
Supplementary Table 3 from Phosphotyrosine Signaling Analysis in Human Tumors Is Confounded by Systemic Ischemia-Driven Artifacts and Intra-Specimen Heterogeneity
Authors: Gajadhar Aaron S. , Johnson Hannah , Slebos Robbert J.C. , Shaddox Kent , Wiles Kerry , Washington Mary Kay , Herline Alan J. , Levine Douglas A. , Liebler Daniel C. , White Forest M.
Published: April 2023

Supplementary Table 3. Summary of similar ischemia response temporal patterns observed across multiple ovarian tumors, as shown in Supplementary Figure 4.
Supplemental Figure S2 from Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem–like Cells
Authors: Giraud Julie , Failla Laura M. , Pascussi Jean-Marc , Lagerqvist Ebba L. , Ollier Jérémy , Finetti Pascal , Bertucci François , Ya Chu , Gasmi Imène , Bourgaux Jean-François , Prudhomme Michel , Mazard Thibault , Ait-Arsa Imade , Houhou Leila , Birnbaum Daniel , Pélegrin André , Vincent Charles , Ryall James G. , Joubert Dominique , Pannequin Julie , Hollande Frédéric
Published: April 2023

Progastrin inhibition decreases colonosphere incidence, CSC frequency and ALDHhigh cell proportion in vitro.
Supplementary Figure 6 from Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB–Controlled Oxidative Stress Responses
Authors: Shono Yusuke , Tuckett Andrea Z. , Liou Hsiou-Chi , Doubrovina Ekaterina , Derenzini Enrico , Ouk Samedy , Tsai Jennifer J. , Smith Odette M. , Levy Emily R. , Kreines Fabiana M. , Ziegler Carly G.K. , Scallion Mary I. , Doubrovin Mikhail , Heller Glenn , Younes Anas , O'Reilly Richard J. , van den Brink Marcel R.M. , Zakrzewski Johannes L.
Published: April 2023

c-Rel inhibitor treatment is associated with partial recovery of lost body weight during severe acute GVHD.
Supplemental Figure 4 from M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers
Authors: Ohashi Yoshimi , Okamura Mutsumi , Hirosawa Asaka , Tamaki Naomi , Akatsuka Akinobu , Wu Kuo-Ming , Choi Hyeong-Wook , Yoshimatsu Kentaro , Shiina Isamu , Yamori Takao , Dan Shingo
Published: April 2023

The effect of M-COPA on cell surface expression of BCRP1 and P-glycoprotein (MDR1).
Supplemental Figure 2 from M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers
Authors: Ohashi Yoshimi , Okamura Mutsumi , Hirosawa Asaka , Tamaki Naomi , Akatsuka Akinobu , Wu Kuo-Ming , Choi Hyeong-Wook , Yoshimatsu Kentaro , Shiina Isamu , Yamori Takao , Dan Shingo
Published: April 2023

Effect of M-COPA on cell surface expression and phosphorylation status of HER3 in MKN-45 cells.
Supplementary Figure Legends from IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis
Authors: Brooks Gavin D. , McLeod Louise , Alhayyani Sultan , Miller Alistair , Russell Prudence A. , Ferlin Walter , Rose-John Stefan , Ruwanpura Saleela , Jenkins Brendan J.
Published: April 2023

Legends for supplementary figures.
Supplementary Table S4 from Quantitative Phosphotyrosine Profiling of Patient-Derived Xenografts Identifies Therapeutic Targets in Pediatric Leukemia
Authors: Dolai Sibasish , Sia Keith C.S. , Robbins Alissa K. , Zhong Ling , Heatley Sue L. , Vincent Tiffaney L. , Hochgräfe Falko , Sutton Rosemary , Kurmasheva Raushan T. , Revesz Tamas , White Deborah L. , Houghton Peter J. , Smith Malcolm A. , Teachey David T. , Daly Roger J. , Raftery Mark J. , Lock Richard B.
Published: April 2023

Average normalized ratios (PDX/SILAC) of all p(STY) the quantifiable Class I phosphosites in 16 PDXs
Supplementary Methods and References from Quantitative Phosphotyrosine Profiling of Patient-Derived Xenografts Identifies Therapeutic Targets in Pediatric Leukemia
Authors: Dolai Sibasish , Sia Keith C.S. , Robbins Alissa K. , Zhong Ling , Heatley Sue L. , Vincent Tiffaney L. , Hochgräfe Falko , Sutton Rosemary , Kurmasheva Raushan T. , Revesz Tamas , White Deborah L. , Houghton Peter J. , Smith Malcolm A. , Teachey David T. , Daly Roger J. , Raftery Mark J. , Lock Richard B.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Table 1 from Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer
Authors: Dou Qianhui , Chen Hai-Ning , Wang Kui , Yuan Kefei , Lei Yunlong , Li Kai , Lan Jiang , Chen Yan , Huang Zhao , Xie Na , Zhang Lu , Xiang Rong , Nice Edouard C. , Wei Yuquan , Huang Canhua
Published: April 2023

Supplementary Table 1
Supplemental Figure Legend from Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus
Authors: Camp Nicola J. , Lin Wei-Yu , Bigelow Alex , Burghel George J. , Mosbruger Timothy L. , Parry Marina A. , Waller Rosalie G. , Rigas Sushilaben H. , Tai Pei-Yi , Berrett Kristofer , Rajamanickam Venkatesh , Cosby Rachel , Brock Ian W. , Jones Brandt , Connley Dan , Sargent Robert , Wang Guoying , Factor Rachel E. , Bernard Philip S. , Cannon-Albright Lisa , Knight Stacey , Abo Ryan , Werner Theresa L. , Reed Malcolm W.R. , Gertz Jason , Cox Angela
Published: April 2023

Supplemental Figure Legend
Supplementary Methods from Germinal Centers Determine the Prognostic Relevance of Tertiary Lymphoid Structures and Are Impaired by Corticosteroids in Lung Squamous Cell Carcinoma
Authors: Siliņa Karīna , Soltermann Alex , Attar Farkhondeh Movahedian , Casanova Ruben , Uckeley Zina M. , Thut Helen , Wandres Muriel , Isajevs Sergejs , Cheng Phil , Curioni-Fontecedro Alessandra , Foukas Periklis , Levesque Mitchell P. , Moch Holger , Linē Aija , van den Broek Maries
Published: April 2023

Contains additional information about the histological, immunostaining, gene expression analysis and animal experiments.
Supplementary Materials and Methods from Endothelial Side Population Cells Contribute to Tumor Angiogenesis and Antiangiogenic Drug Resistance
Authors: Naito Hisamichi , Wakabayashi Taku , Kidoya Hiroyasu , Muramatsu Fumitaka , Takara Kazuhiro , Eino Daisuke , Yamane Keitaro , Iba Tomohiro , Takakura Nobuyuki
Published: April 2023

Supplementary Materials and Methods
Supplemental Figure 4 Effects of TRIM3 upregulating and downregulation in mammalian models. from Drosophila Brat and Human Ortholog TRIM3 Maintain Stem Cell Equilibrium and Suppress Brain Tumorigenesis by Attenuating Notch Nuclear Transport
Authors: Mukherjee Subhas , Tucker-Burden Carol , Zhang Changming , Moberg Kenneth , Read Renee , Hadjipanayis Costas , Brat Daniel J.
Published: April 2023

(A) Western blot of N08-74 VC and N08-74-TRIM3 expressing cells and 13113 VC and 13113-TRIM3 expressing cells. TRIM3 expression does not increase the glial cell marker GFAP or neuronal marker TUJ-1. (B) TRIM3 sh-RNA in NHNP cells reduces the TRIM3 expression. TRIM3 suppression does not increase total or cytosolic NICD but increases NICD nuclear localization (B,C,D). Nuclear and cytosolic extracts show presence of TRIM3 in the cytosol, but not in nucleus (E).
Supplementary figure 1 from A Preclinical Model of Chronic Alcohol Consumption Reveals Increased Metastatic Seeding of Colon Cancer Cells in the Liver
Authors: Im Hwi-Jin , Kim Hyeong-Geug , Lee Jin-Seok , Kim Hyo-Seon , Cho Jung-Hyo , Jo Il-Joo , Park Sung-Joo , Son Chang-Gue
Published: April 2023

Experimental models
Figure S3 from Nkx2.8 Inhibits Epithelial–Mesenchymal Transition in Bladder Urothelial Carcinoma via Transcriptional Repression of Twist1
Authors: Yu Chunping , Liu Zhuowei , Chen Qiuhong , Li Yonghong , Jiang Lijuan , Zhang Zhiling , Zhou Fangjian
Published: April 2023

Silencing endogenous Nkx2.8 enhances the motility of UC cells
Supplemental Figure Legends from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Figure legends for supplemental Figures S1-S6.
Figure S6 from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Multivariate statistics for eicosanoid profiles.
Figure S2 from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Relative abundances of free fatty acids, phosphatidylglycerols and phosphatidylinositols in tumour compared to normal lung tissue.
Figure S1 from Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer
Authors: Hall Zoe , Ament Zsuzsanna , Wilson Catherine H. , Burkhart Deborah L. , Ashmore Tom , Koulman Albert , Littlewood Trevor , Evan Gerard I. , Griffin Julian L.
Published: April 2023

Clustering of MALDI imaging dataset for a lung section.
Supplementary Materials and Methods, Supplementary Tables 1 through 3, and Supplementary Figure 1 from The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models
Authors: Oplustil O'Connor Lenka , Rulten Stuart L. , Cranston Aaron N. , Odedra Rajesh , Brown Henry , Jaspers Janneke E. , Jones Louise , Knights Charlotte , Evers Bastiaan , Ting Attilla , Bradbury Robert H. , Pajic Marina , Rottenberg Sven , Jonkers Jos , Rudge David , Martin Niall M.B. , Caldecott Keith W. , Lau Alan , O'Connor Mark J.
Published: April 2023

Supplementary materials and methods. Suppl Table 1. MMS combination PF50 cell line assays. Concentration-dependent potentiation of MMS (PF50 ratios). Suppl Table 2. Permeability of AZD2461 and olaparib were assessed. Suppl Table 3. Activity of olaparib and AZD2461 alone or in combination with the P-gp inhibitor verapamil in the colorectal cancer cell line HCT-15, which expresses high levels of P-gp. Suppl Fig. 1. Immunofluorescence for poly(ADP-ribose) in human A549 cells. Suppl Fig. 2. Analysis of both in vivo pharmacokinetics (PK) and pharmacodynamics (PD) in tumors taken from SW620 (human colon carcinoma) xenograft-bearing mice. Suppl Fig. 3. Colony formation (clonogenic) assays in the intrinsically high P-gp-expressing MRE11-deficient HCT-15 human colorectal cell line. Suppl. Fig. 4. Combination efficacy studies. Suppl Fig. 5. Relative body weight changes in mice following treatment with 10 mg/kg AZD2461 and olaparib in combination with temozolomide. Suppl. Fig. 6. A serial dilution of RNA concentration was used to establish a standard curve for determining the reaction efficiency of PARP1, PARP2, PARP3, and housekeeper gene (PPIA: cyclophilin A) TaqMan RT-PCR assays in both rat and mouse species; Determination of optimal reference gene for rat-mouse data normalization. Suppl Fig. 7.A. A serial dilution of reference RNA (Qiagen) concentration was used to establish a standard curve for determining the reaction efficiency of PARP3 and housekeeper genes (PPIA: cyclophilin and YWHAZ: tyrosine 3-monooxygenase/tryptohpan 5-monooxygenase activation protein, zeta polypeptide) SybrGreen RT-PCR assays in both rat and human species; Determination of optimal reference gene for rat-human data normalization. Suppl Fig. 8. Relative body weight changes in rat following treatment with 10 mg/kg AZD2461 and olaparib in combination with temozolomide; Relative body weight changes in rat following treatment with 20 mg/kg AZD2461 and olaparib in combination with temozolomide.
Figure S2 from RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis
Authors: Lee Min-Goo , Jeong Seong-In , Ko Kyung-Phil , Park Soon-Ki , Ryu Byung-Kyu , Kim Ick-Young , Kim Jeong-Kook , Chi Sung-Gil
Published: April 2023

Figure S2. RASSF1A interacts with RhoA. A, No interaction between RASSF1A and active Ras proteins. HeLa cells were transfected with HA-tagged H-Ras-G14V, K-Ras-G14V, or N-Ras-Q61R. Immunoprecipitation and immunoblots were performed as indicated. B, Characterization of RASSF1A-binding region of RhoA. C, No RhoA inhibition activity of RASSF1A-R269F. Cells transfected with WT or mutant (R269F) RASSF1A were treated with EGF (10 ng/ml) for 6 h. D, Construction of exon 2Î³-deleted RASSF1C mutant (Î”2Î³). E, IP assay showing RhoA interaction with RASSF1C-Î”2Î³ but not with WT-RASSF1C.
Supplementary Methods from Brain-Mimetic 3D Culture Platforms Allow Investigation of Cooperative Effects of Extracellular Matrix Features on Therapeutic Resistance in Glioblastoma
Authors: Xiao Weikun , Zhang Rongyu , Sohrabi Alireza , Ehsanipour Arshia , Sun Songping , Liang Jesse , Walthers Christopher M. , Ta Lisa , Nathanson David A. , Seidlits Stephanie K.
Published: April 2023

Supplementary Methods describing additional information for procedures in manuscript, including hydrogel fabrication, hydrogel sample cryopreservation, lentivirus preparation, mechanical characterization, diffusion, western blotting, and statistics.
Supplemental Figure 2 from Cyclin A1 and P450 Aromatase Promote Metastatic Homing and Growth of Stem-like Prostate Cancer Cells in the Bone Marrow
Authors: Miftakhova Regina , Hedblom Andreas , Semenas Julius , Robinson Brian , Simoulis Athanasios , Malm Johan , Rizvanov Albert , Heery David M. , Mongan Nigel P. , Maitland Norman J. , Allegrucci Cinzia , Persson Jenny L.
Published: April 2023

Evaluate bone marrow metastasis initiated by PC3M cells via intracardiac injection of tumor cells into mice.
Supplemental Figure 8 from JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma
Authors: Chan Tiffany Sin Yu , Hawkins Cynthia , Krieger Jonathan R. , McGlade C. Jane , Huang Annie
Published: April 2023

Correlation of JPO2 and LEDGF/p75 transcript levels in MB subtypes
Supplemental Figures and Tables from Notch4 Signaling Induces a Mesenchymal–Epithelial–like Transition in Melanoma Cells to Suppress Malignant Behaviors
Authors: Bonyadi Rad Ehsan , Hammerlindl Heinz , Wels Christian , Popper Ulrich , Ravindran Menon Dinoop , Breiteneder Heimo , Kitzwoegerer Melitta , Hafner Christine , Herlyn Meenhard , Bergler Helmut , Schaider Helmut
Published: April 2023

SF1: Phenotypic and functional changes of 451Lu, WM9 and WM164 following N4ICD overexpression SF2: Immunoblots and immunohistochemistry of EMT markers and Notch4 SF3: Details of CSL binding to Snail2 and Twist1 promoter regions SF4: Immunoblots of overexpression and silencing experiments confirming the Notch4-Hey1/2-Snail2/Twist1 axis (SF4) SF5: Immunoblots of pLNCX-N4ICD and siHey1/2 transduced cells and details of Snail2 and Twist1 promoter regions ST1: Plasmids and siRNAs ST2: Antibodies ST3: Primers for qPCR and ChIP ST4: Sequence of EMSA fragments ST5: Sequence of luciferase fragments ST6: Fold regulation of EMT markers determined by PCR-array ST7: Details of immunohistochemical analyses of melanoma samples Supplementary references
Supplemental Figures from PINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma
Authors: Agnihotri Sameer , Golbourn Brian , Huang Xi , Remke Marc , Younger Susan , Cairns Rob A. , Chalil Alan , Smith Christian A. , Krumholtz Stacey-Lynn , Mackenzie Danielle , Rakopoulos Patricia , Ramaswamy Vijay , Taccone Michael S. , Mischel Paul S. , Fuller Gregory N. , Hawkins Cynthia , Stanford William L. , Taylor Michael D. , Zadeh Gelareh , Rutka James T.
Published: April 2023

Supplemental Figure 1: Related to Figure 1: Characterization of Gene-Trapped Clones Supplemental Figure 2 Related to Figure 2: PINK1 alters normal astrocyte metabolism Supplemental Figure 3 Related to Figure 2: PINK1 alters normal astrocyte metabolism Supplemental Figure 4: Related to Figure 3: PINK1 alters normal astrocyte metabolism and stabilizes HIF1a Supplemental Figure 5: Related to Figure 3: PINK1 overexpression stops GBM cell growth and inhibits glycolysis. Supplemental Figure 6: Related to Figure 3: PINK1 overexpression inhibits glycolysis. Supplemental Figure 7: Related to Figure 3: PINK1 overexpression inhibits glycolysis. Supplemental Figure 8: Related to Figure 4: Selective targeting in PINK1 expressing GBM cells leads to reduced viability Supplemental Figure 9: Related to Figure 4: Targeting of PINK1 in GBM cells leads to reduced colony formation and caspase activity Supplemental Figure 10: Related to Figure 5 and 6. PINK1 expression in vivo. Supplemental Table 1: Genes identified from gene-trap screen.
Supplementary Figure Legends from An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression
Authors: Hayashi Hiromitsu , Higashi Takaaki , Yokoyama Naomi , Kaida Takayoshi , Sakamoto Keita , Fukushima Yukiko , Ishimoto Takatsugu , Kuroki Hideyuki , Nitta Hidetoshi , Hashimoto Daisuke , Chikamoto Akira , Oki Eiji , Beppu Toru , Baba Hideo
Published: April 2023

Supplementary Figure Legends
Supplemental Figure 3: High MS-444 concentrations impede intestinal epithelial re-epithelialization and induce HuR nucleocytoplasmic shuttling in an acute colitis model. from HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis
Authors: Lang Michaela , Berry David , Passecker Katharina , Mesteri Ildiko , Bhuju Sabin , Ebner Florian , Sedlyarov Vitaly , Evstatiev Rayko , Dammann Kyle , Loy Alexander , Kuzyk Orest , Kovarik Pavel , Khare Vineeta , Beibel Martin , Roma Guglielmo , Meisner-Kober Nicole , Gasche Christoph
Published: April 2023

HuR nucleocytoplasmic shuttling is increased with increasing MS-444 concentrationsin an acute colitis model.
Supplemental figure 2 from An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression
Authors: Hayashi Hiromitsu , Higashi Takaaki , Yokoyama Naomi , Kaida Takayoshi , Sakamoto Keita , Fukushima Yukiko , Ishimoto Takatsugu , Kuroki Hideyuki , Nitta Hidetoshi , Hashimoto Daisuke , Chikamoto Akira , Oki Eiji , Beppu Toru , Baba Hideo
Published: April 2023

Changes in cyclin D1 mRNA expression by TAZ knockdown in HCC cells
Supplementary methods from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary file containing the supplementary methods
Supplementary Figure 5. from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary Figure 5. Low dose PTX did not affect cytoskeletal integrity of EGI-1 cells.
Supplementary Figure 4. from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary Figure 4. Low dose PTX did not affect Rac-1 GTP levels, while it reduced the MT1-MMP membrane expression.
Suppl Figure 2 from HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Authors: Budina-Kolomets Anna , Webster Marie R. , Leu Julia I-Ju , Jennis Matthew , Krepler Clemens , Guerrini Anastasia , Kossenkov Andrew V. , Xu Wei , Karakousis Giorgos , Schuchter Lynn , Amaravadi Ravi K. , Wu Hong , Yin Xiangfan , Liu Qin , Lu Yiling , Mills Gordon B. , Xu Xiaowei , George Donna L. , Weeraratna Ashani T. , Murphy Maureen E.
Published: April 2023

Kaplan-Meier analysis of data from PrognoScan on the level of HSP70 (A1B) mRNA and survival.
Supplementary figures from DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster
Authors: Zagorac Sladjana , Alcala Sonia , Fernandez Bayon Gustavo , Bou Kheir Tony , Schoenhals Matthieu , González-Neira Anna , Fernandez Fraga Mario , Aicher Alexandra , Heeschen Christopher , Sainz Bruno
Published: April 2023

Supplementary figures and tables: Supplementary Figure S1. Autofluoresecnce as a biomarker for the isolation of pancreatic cancer stem cells. Results related to Figure 1. Supplementary Figure S2. PDAC CSCs over-express DNMT1 and bear higher 5mC levels. Results related to Figure 1 and Figure 2. Supplementary Figure S3. The DNMT1 inhibitor Zebularine decreases CSC phenotypes. Related to Figure 3. Supplementary Figure S4. The DNMT1 inhibitor Decitabine decreases CSC phenotypes. Related to Figure 3. Supplementary Figure S5. DNMT1 inhibitor Zebularine promotes CSC differentiation. Related to Figure 5. Supplementary Figure S6. DNMT1 inhibition modulates expression of miR-203, miR-205, and the miR-17-92 cluster. Related to Figure 6. Table S1. Table showing decreased DNA methylation for miRs following Zebularine treatment, represented as fold changes. Table S2. Table showing decreased DNA methylation of genes upon Zebularine treatment, represented as fold changes. Table S3. Table showing decreased DNA methylation of genes upon Zebularine treatment, represented as fold changes.
Supplementary Tables S1-S2 from Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade
Authors: Chen Michelle B. , Lamar John M. , Li Ran , Hynes Richard O. , Kamm Roger D.
Published: April 2023

Sequences of the miR-30-based shRNAs targeting different human (for MDA-MB-231, A-375 MA2, SUM 159) or mouse (for 4T1) integrin subunits used in this study ; 4T1 cells stably expressing miR30-based shRNAs targeting the indicated integrin subunits were assayed at least 3 times by live-cell flow cytometry for surface expression of the indicated integrin .
Supplementary figures S1-10 from Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1
Authors: Ann Eun-Jung , Kim Mi-Yeon , Yoon Ji-Hye , Ahn Ji-Seon , Jo Eun-Hye , Lee Hye-Jin , Lee Hyun-Woo , Kang Hyeok-Gu , Choi Dong Wook , Chun Kyung-Hee , Lee Ji Shin , Choi Cheol Yong , Ferrando Adolfo A. , Lee Keesook , Park Hee-Sae
Published: April 2023

Supplementary Figure 1: ADR suppresses Notch1 signaling. Supplementary Figure 2: ADR inhibits the transcriptional activity of Notch1 by inducing HIPK2. Supplementary Figure 3: HIPK2 regulates the Notch1-IC protein stability through proteasomal degradation pathways. Supplementary Figure 4: HIPK2 facilitates Notch1-IC degradation by Fbw7 ubiquitin ligase. Supplementary Figure 5: HIPK2 physically interacts with Notch1-IC. Supplementary Figure 6: HIPK2 phosphorylates Notch1-IC at the T2512 residue. Supplementary Figure 7: HIPK2-mediated downregulation of Notch1-IC suppresses the tumorigenesis of breast cancer. Supplementary Figure 8: Somatic mutations in the CPD motif of Notch1-IC make it resistant to HIPK2. Supplementary Figure 9: Physiological effects of somatic mutations in the CPD motif of Notch1-IC. Supplementary Figure 10: A propose model of Notch1 signaling pathway regulation by HIPK2 in cancer during chemotherapy.
Supplementary figure legends from Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1
Authors: Ann Eun-Jung , Kim Mi-Yeon , Yoon Ji-Hye , Ahn Ji-Seon , Jo Eun-Hye , Lee Hye-Jin , Lee Hyun-Woo , Kang Hyeok-Gu , Choi Dong Wook , Chun Kyung-Hee , Lee Ji Shin , Choi Cheol Yong , Ferrando Adolfo A. , Lee Keesook , Park Hee-Sae
Published: April 2023

Supplementary figure legends
Figure S3 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: April 2023

KDM5i alone and in combination with DAC upregulates cancer hallmark & immunomodulatory pathways
Supplementary Tables 2, 3 and 4 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: April 2023

Supplementary Table 2: Clinical-pathological data for colorectal cancer patients used for genomic analysis and validation Supplementary Table 3: Clinical-pathological data for colorectal liver metastasis patients used for genomic analysis and validation Supplementary Table 4: Clinical-pathological data for renal cancer patients used for genomic analysis and validation
Supplementary Table 8 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: April 2023

Supplementary Table 8: Key clinical data for clear cell RCC cohort 1, showing overall survival (OS)
Supplementary Table S4 from Measurement of Endogenous versus Exogenous Formaldehyde–Induced DNA–Protein Crosslinks in Animal Tissues by Stable Isotope Labeling and Ultrasensitive Mass Spectrometry
Authors: Lai Yongquan , Yu Rui , Hartwell Hadley J. , Moeller Benjamin C. , Bodnar Wanda M. , Swenberg James A.
Published: April 2023

6 ppm NHP Exposure Results.
Supplementary Table 11 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: April 2023

Supplementary Table 11: Key clinical data for the CRC cohort showing overall survival (OS)
Legends for Supplementary Documents from Cholesterol Metabolism and Prostate Cancer Lethality
Authors: Stopsack Konrad H. , Gerke Travis A. , Sinnott Jennifer A. , Penney Kathryn L. , Tyekucheva Svitlana , Sesso Howard D. , Andersson Swen-Olof , Andrén Ove , Cerhan James R. , Giovannucci Edward L. , Mucci Lorelei A. , Rider Jennifer R.
Published: April 2023

Titles/legends for Supplementary Figure 1 and Supplementary Table 1
Supplementary Table 8 from An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers
Authors: Prueitt Robyn L. , Wallace Tiffany A. , Glynn Sharon A. , Yi Ming , Tang Wei , Luo Jun , Dorsey Tiffany H. , Stagliano Katherine E. , Gillespie John W. , Hudson Robert S. , Terunuma Atsushi , Shoe Jennifer L. , Haines Diana C. , Yfantis Harris G. , Han Misop , Martin Damali N. , Jordan Symone V. , Borin James F. , Naslund Michael J. , Alexander Richard B. , Stephens Robert M. , Loffredo Christopher A. , Lee Dong H. , Putluri Nagireddy , Sreekumar Arun , Hurwitz Arthur A. , Ambs Stefan
Published: April 2023

Supplemetary Table 8: Genes differently expressed between current and never in microdissected tumors using the Bioconductor limma R package.
Supplementary Table 11 from An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers
Authors: Prueitt Robyn L. , Wallace Tiffany A. , Glynn Sharon A. , Yi Ming , Tang Wei , Luo Jun , Dorsey Tiffany H. , Stagliano Katherine E. , Gillespie John W. , Hudson Robert S. , Terunuma Atsushi , Shoe Jennifer L. , Haines Diana C. , Yfantis Harris G. , Han Misop , Martin Damali N. , Jordan Symone V. , Borin James F. , Naslund Michael J. , Alexander Richard B. , Stephens Robert M. , Loffredo Christopher A. , Lee Dong H. , Putluri Nagireddy , Sreekumar Arun , Hurwitz Arthur A. , Ambs Stefan
Published: April 2023

Supplementary Table S11: Differentially expressed genes comparing prostate tumors from nicotine-treated TRAMP mice with tumors from untreated mice (reference).
Supplementary Tables S1-S3 from Early Prediction of Cancer Progression by Depth-Resolved Nanoscale Mapping of Nuclear Architecture from Unstained Tissue Specimens
Authors: Uttam Shikhar , Pham Hoa V. , LaFace Justin , Leibowitz Brian , Yu Jian , Brand Randall E. , Hartman Douglas J. , Liu Yang
Published: April 2023

Supplementary Tables S1-S3: Statistical comparison of basic clinical factors between low-risk and high-risk colitis patients who underwent surveillance colonoscopy with more than one year of follow-up (S1); Detailed clinical information and pathological grading of colitis patients who underwent surveillance colonoscopy with more than one year of follow-up (S2); Statistical analysis (low-risk vs. high-risk patient group) of 12 quantitative microscale image features of cell nuclei from the initial biopsies of surveillance colonoscopy of colitis patients (S3).
Supplementary Figure 7 from Checkpoint Antibodies but not T Cell–Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation
Authors: Hettich Michael , Lahoti Jayashree , Prasad Shruthi , Niedermann Gabriele
Published: April 2023

Cell death/apoptosis of activated CD4+ T cells upon bsAb-mediated restimulation in vitro.
Supplementary Table and Figure Legends from Early Prediction of Cancer Progression by Depth-Resolved Nanoscale Mapping of Nuclear Architecture from Unstained Tissue Specimens
Authors: Uttam Shikhar , Pham Hoa V. , LaFace Justin , Leibowitz Brian , Yu Jian , Brand Randall E. , Hartman Douglas J. , Liu Yang
Published: April 2023

Supplementary Table and Figure Legends: Legends for Supplementary Tables S1-S3 and Supplementary Figures S1-S12.
Supplementary Figure 1 from Checkpoint Antibodies but not T Cell–Recruiting Diabodies Effectively Synergize with TIL-Inducing γ-Irradiation
Authors: Hettich Michael , Lahoti Jayashree , Prasad Shruthi , Niedermann Gabriele
Published: April 2023

AC133xCD3 bsAb binds to its targets in vivo and activates tumor-resident T cells.
Supplementary Table S1 from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

List of gene symbols with gene expression levels, fold change values and adjusted p-values (padj; q-value) derived from RNA-seq analyses.
Supplementary Figure 1 from Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome
Authors: You Sungyong , Knudsen Beatrice S. , Erho Nicholas , Alshalalfa Mohammed , Takhar Mandeep , Al-deen Ashab Hussam , Davicioni Elai , Karnes R. Jeffrey , Klein Eric A. , Den Robert B. , Ross Ashley E. , Schaeffer Edward M. , Garraway Isla P. , Kim Jayoung , Freeman Michael R.
Published: April 2023

Boxplots depict distinct pathway activities between the subtypes.
Supplementary Figure S1 from Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Authors: Kress Theresia R. , Pellanda Paola , Pellegrinet Luca , Bianchi Valerio , Nicoli Paola , Doni Mirko , Recordati Camilla , Bianchi Salvatore , Rotta Luca , Capra Thelma , Ravà Micol , Verrecchia Alessandro , Radaelli Enrico , Littlewood Trevor D. , Evan Gerard I. , Amati Bruno
Published: April 2023

tet-Myc induction in utero leads to fast and highly penetrant tumorigenesis.
Legends for Supplementary Figures from Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome
Authors: You Sungyong , Knudsen Beatrice S. , Erho Nicholas , Alshalalfa Mohammed , Takhar Mandeep , Al-deen Ashab Hussam , Davicioni Elai , Karnes R. Jeffrey , Klein Eric A. , Den Robert B. , Ross Ashley E. , Schaeffer Edward M. , Garraway Isla P. , Kim Jayoung , Freeman Michael R.
Published: April 2023

Legends for Supplementary Figures.
Supplementary Table S1 from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

Clinical Information for CPCTR TMAs
Supplementary Figure S7 from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

Nestin expression in human MB
Supplementary References from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

References indicating the functions of candidates whose expressions are affected following the alterations of CNTN1 expression
Supplementary Figure S6 from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

Ciliogenesis among GNPs and NIH3T3 cells after Nestin expression.
Supplementary Figure legends from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

Detailed legends for supplementary Figures
Supplementary Figure 4 from Neural Cell Adhesion Protein CNTN1 Promotes the Metastatic Progression of Prostate Cancer
Authors: Yan Judy , Ojo Diane , Kapoor Anil , Lin Xiaozeng , Pinthus Jehonathan H. , Aziz Tariq , Bismar Tarek A. , Wei Fengxiang , Wong Nicholas , De Melo Jason , Cutz Jean-Claude , Major Pierre , Wood Geoffrey , Peng Hao , Tang Damu
Published: April 2023

IHC staining for CNTN1 and PAP expression on 8 bone metastatic prostate cancer tissues
Supplementary Figure S2 from Nestin Mediates Hedgehog Pathway Tumorigenesis
Authors: Li Peng , Lee Eric H. , Du Fang , Gordon Renata E. , Yuelling Larra W. , Liu Yongqiang , Ng Jessica M.Y. , Zhang Hao , Wu Jinhua , Korshunov Andrey , Pfister Stefan M. , Curran Tom , Yang Zeng-jie
Published: April 2023

ptch1-deficient GNPs develop MB upon transplantation
Fig S6 from Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Authors: Cormerais Yann , Giuliano Sandy , LeFloch Renaud , Front Benoît , Durivault Jerome , Tambutté Eric , Massard Pierre-André , de la Ballina Laura Rodriguez , Endou Hitoshi , Wempe Michael F. , Palacin Manuel , Parks Scott K. , Pouyssegur Jacques
Published: April 2023

Figure S6: Tumorigenicity and mTORC1 activity of WT and double CD98KO/ LAT1KO cells.
Fig S4 from Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Authors: Cormerais Yann , Giuliano Sandy , LeFloch Renaud , Front Benoît , Durivault Jerome , Tambutté Eric , Massard Pierre-André , de la Ballina Laura Rodriguez , Endou Hitoshi , Wempe Michael F. , Palacin Manuel , Parks Scott K. , Pouyssegur Jacques
Published: April 2023

Figure S4: LAT1 activity is a key limiting step for AA homeostasis and proliferation in multiple cancer types.
Fig S3 from Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Authors: Cormerais Yann , Giuliano Sandy , LeFloch Renaud , Front Benoît , Durivault Jerome , Tambutté Eric , Massard Pierre-André , de la Ballina Laura Rodriguez , Endou Hitoshi , Wempe Michael F. , Palacin Manuel , Parks Scott K. , Pouyssegur Jacques
Published: April 2023

Figure S3: Disruption of CD98 in A549 cell line has not impact on AA sensing pathways and proliferation.
Fig S2 from Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
Authors: Cormerais Yann , Giuliano Sandy , LeFloch Renaud , Front Benoît , Durivault Jerome , Tambutté Eric , Massard Pierre-André , de la Ballina Laura Rodriguez , Endou Hitoshi , Wempe Michael F. , Palacin Manuel , Parks Scott K. , Pouyssegur Jacques
Published: April 2023

Figure S2: Phenotypic analysis of the genetic disruption of LAT1 in the lung adenocarcinoma cell line: A549
Supplemental Table S1 from Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells
Authors: Timaner Michael , Letko-Khait Nitzan , Kotsofruk Ruslana , Benguigui Madeleine , Beyar-Katz Ofrat , Rachman-Tzemah Chen , Raviv Ziv , Bronshtein Tomer , Machluf Marcelle , Shaked Yuval
Published: April 2023

Fold change in the expression levels of factors secreted by gemcitabine-educated versus untreated MSCs
Supplemental Figures from Therapy-Educated Mesenchymal Stem Cells Enrich for Tumor-Initiating Cells
Authors: Timaner Michael , Letko-Khait Nitzan , Kotsofruk Ruslana , Benguigui Madeleine , Beyar-Katz Ofrat , Rachman-Tzemah Chen , Raviv Ziv , Bronshtein Tomer , Machluf Marcelle , Shaked Yuval
Published: April 2023

Supplemental Figures S1-7 supporting figures 1-6. Figure S1: Tumor growth in mice coâ€�implanted with gemcitabineâ€�educated MSCs and PANC1 cells. Figure S2: Viability and survival of TICs and MSCs in response to chemotherapy. Figure S3: TIC enrichment in pancreatic cancer cells cultured with conditioned medium obtained from gemcitabineâ€�educated MSCs. Figure S4: Sphere formation of pancreatic cancer cells in the presence of conditioned medium obtained from gemcitabineâ€�educated MSCs. Figure S5: Gemcitabineâ€�educated MSCs promote PANC1 tumor growth. Figure S6: TIC enrichment in the presence of recombinant CXCL10. Figure S7: Densitometry analysis of expression of proteins from different signaling pathways.
Supplementary Table 1 from Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients
Authors: De Monte Lucia , Wörmann Sonja , Brunetto Emanuela , Heltai Silvia , Magliacane Gilda , Reni Michele , Paganoni Anna Maria , Recalde Helios , Mondino Anna , Falconi Massimo , Aleotti Francesca , Balzano Gianpaolo , Algül Hana , Doglioni Claudio , Protti Maria Pia
Published: April 2023

Multivariate Cox regression analysis of the influence of the percentage of basophils in TDLNs on the survival of 35 stage IB-III pancreatic cancer patients after surgery.
supplementary Materials and Methods from miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis
Authors: Xue Jianfei , Zhou Aidong , Wu Yamei , Morris Saint-Aaron , Lin Kangyu , Amin Samirkumar , Verhaak Roeland , Fuller Gregory , Xie Keping , Heimberger Amy B. , Huang Suyun
Published: April 2023

supplementary Materials and Methods
Supplementary Figures S1-S10 from Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma
Authors: Hijiya Naoki , Tsukamoto Yoshiyuki , Nakada Chisato , Tung Nguyen Lam , Kai Tomoki , Matsuura Keiko , Shibata Kohei , Inomata Masafumi , Uchida Tomohisa , Tokunaga Akinori , Amada Kohei , Shirao Kuniaki , Yamada Yasunari , Mori Hiromu , Takeuchi Ichiro , Seto Masao , Aoki Masahiro , Takekawa Mutsuhiro , Moriyama Masatsugu
Published: April 2023

Rates of concordance between CIS regions of IPMN-inv and paired or non-paired invasive regions of IPMN-inv (S1); Genome-wide frequency of genomic imbalance in IDC (S2); Genome-wide frequency of genomic imbalance in pancreatic ductal carcinoma cell lines (S3); Validation of microarray data by quantitative real-time PCR (S4); Production of lentiviruses encoding each of the 9 genes (S5); Establishment of DUSP4 re-expressing stable clones (S6); Orthotopic xenograft model mice transplanted with PANC-1/cont and PANC-1/DUSP4-2 (S7); The effects of MAPKs inhibition on proliferation, resistance of anoikis, invasiveness, and motility of PANC-1 cells (S8); Inducible expression of DUSP4 in immortalized human pancreatic duct cell lines (S9); DUSP4 expression in IDCs and their accompanying PanINs (S10).
Supplementary Table and Figure Legends from Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
Authors: Pasero Christine , Gravis Gwenaëlle , Guerin Mathilde , Granjeaud Samuel , Thomassin-Piana Jeanne , Rocchi Palma , Paciencia-Gros Maria , Poizat Flora , Bentobji Mélanie , Azario-Cheillan Francine , Walz Jochen , Salem Naji , Brunelle Serge , Moretta Alessandro , Olive Daniel
Published: April 2023

Legend for Supplementary Tables S1-S2 and Supplementary Figures S1-S4.
Supplementary Table S2 from Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
Authors: Pasero Christine , Gravis Gwenaëlle , Guerin Mathilde , Granjeaud Samuel , Thomassin-Piana Jeanne , Rocchi Palma , Paciencia-Gros Maria , Poizat Flora , Bentobji Mélanie , Azario-Cheillan Francine , Walz Jochen , Salem Naji , Brunelle Serge , Moretta Alessandro , Olive Daniel
Published: April 2023

List of the antibodies (Name, Clone, Provider) and isotype controls used for NK cell phenotype and functional experiments.
Supplementary Figure S4 from Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
Authors: Pasero Christine , Gravis Gwenaëlle , Guerin Mathilde , Granjeaud Samuel , Thomassin-Piana Jeanne , Rocchi Palma , Paciencia-Gros Maria , Poizat Flora , Bentobji Mélanie , Azario-Cheillan Francine , Walz Jochen , Salem Naji , Brunelle Serge , Moretta Alessandro , Olive Daniel
Published: April 2023

Correlation of mRNA for NK cell markers with prognosis in prostate cancer (public datasets).
Supplementary Figure S3 from Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
Authors: Pasero Christine , Gravis Gwenaëlle , Guerin Mathilde , Granjeaud Samuel , Thomassin-Piana Jeanne , Rocchi Palma , Paciencia-Gros Maria , Poizat Flora , Bentobji Mélanie , Azario-Cheillan Francine , Walz Jochen , Salem Naji , Brunelle Serge , Moretta Alessandro , Olive Daniel
Published: April 2023

Functions of peripheral NK cells from prostate cancer patients.
Supplementary Table S2 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus
Authors: Harlow Matt L. , Maloney Nichole , Roland Joseph , Guillen Navarro Maria Jose , Easton Matthew K. , Kitchen-Goosen Susan M. , Boguslawski Elissa A. , Madaj Zachary B. , Johnson Ben K. , Bowman Megan J. , D'Incalci Maurizio , Winn Mary E. , Turner Lisa , Hostetter Galen , Galmarini Carlos María , Aviles Pablo M. , Grohar Patrick J.
Published: April 2023

Supplementary Table S2 EWS-FLI1 gene signature of 116 induced and 50 repressed targets (3,15).