bluuebunny/crossref_metadata_2025 huggingface dataset:
Produtos Naturais Industrializáveis da Amazônia
Authors: Gilbert B.
Published: October 2022

A Amazônia é freqüentemente citada como uma fonte de produtos naturais, cuja industrialização e venda no mercado mundial poderia trazer benefícios significantes à região. Neste trabalho alguns produtos específicos são apresentados nas classes de medicamentos, óleos e gorduras, inseticidas e repelentes de insetos. Outras classes como gomas, corantes, óleos essenciais e princípios amargos são abordados de maneira breve. Destaque é dado à importância de qualidade, quantidade, fornecimento regular e estabilidade de preço.
A Importância das Técnicas Acopladas (CL/UV, CL/EM, CL/RMN) para Procura de Princípios Ativos
Authors: Queiroz E. F. , Hostettmann K.
Published: October 2022

A natureza representa um extraordinário reservatório de novas moléculas. Nos últimos anos existe um verdadeiro re-interesse nos programas de triagem (screnning) pelos produtos naturais como fonte de novos agentes terapêuticos. Para se descobrir novos produtos naturais ativos, a desreplicação dos extratos brutos é de importância capital para que se possa evitar o isolamento de compostos conhecidos. Neste campo, as estratégias de triagem química, baseadas em técnicas acopladas como a cromatografia líquida-detecção ultravioleta (CL-UV-DAD), cromatografia líquida-espectrometria de massa (CL-MS) e cromatografia líquida-ressonância magnética nuclear (CL-RMN) são cada vez mais utilizadas. No laboratório do Prof. Hostettmann, estes métodos analíticos foram completamente integrados no processo de isolamento e utilizados como na triagem química dos extratos brutos em complemento com ensaios biológicos on-line ou off-line. Neste artigo, possibilidades e limitações das técnicas acopladas na identificação on-line de produtos naturais serão abordadas. Devido a grande importância da CLAE-RMN, uma parte do artigo será dedicada a esta técnica. Em particular várias maneiras de integração da RMN nos processos de desreplicação.
O gênero Croton e Aspectos Relevantes de Diterpenos Clerodanos
Authors: Maciel M. A. M. , Cortez J. K. P. C. , Gomes F. E. S.
Published: October 2022

O gênero Croton (Euphorbiaceae) encontra-se amplamente distribuído em todo o mundo, com concentração significativa na África, Brasil e México. As espécies Croton zambesicus Muell Arg. (África), Croton lechleri Muell Arg. (EUA) e Croton tiglium Klotzsch (Ásia), lideram as pesquisas internacionais com documentação de 58 artigos publicados em periódicos indexados. Dentre as espécies nativas do Brasil, destacam-se o Croton cajucara Benth, Croton zehntneri Pax e Hoffm. e Croton sonderianus Müll Arg. por serem os mais representativos com 86 artigos publicados. O Croton cajucara representa a espécie mais estudada do gênero, perfazendo 60 publicações inseridas em um contexto científico multidisciplinar. A fonte mais abundante de diterpenos do tipo clerodano são plantas pertencentes ao gênero Teucrium (Labiatae). No entanto, os gêneros Ajuga, Scutellaria, Clerodendrum e Croton, representam também, uma fonte rica em clerodanos. As espécies Croton schiedeanus Schlecht, Croton sonderianus e Croton cajucara Benth são exemplos a serem citados, já que nestas espécies, a ocorrência de clerodanos é abundante. Atualmente, o diterpeno do tipo 19-nor-clerodano transdesidrocrotonina (DCTN) por ter sido correlacionado com grande parte das indicações tradicionais de Croton cajucara, é um dos mais representativos desta classe de diterpeno. O presente artigo enfoca aspectos relevantes sobre o gênero Croton e os diterpenos do tipo clerodano, com enfoque especial para os resultados quimiofarmacológicos obtidos para a espécie medicinal Croton cajucara.
The Correction of Multiple Diastemas in Adult Patients with Bad Tongue Habit (A Case Report)
Authors: Sutan Christinawaty , Sofyanti Ervina
Published: October 2022

There are various options in multiple diastemas correction due to the multifactorial malocclusion aetiology. The treatment of this malocclusion is a challenging task for clinicians not only for aesthetic achievement but also for the stability of orthodontic treatment. The multidisciplinary approaches depend on the aetiology of malocclusion and patient compliance. This reported case aims to describe the correction of multiple diastemas in adult patients with bad tongue habits. A 27-year-old male patient came to dental hospital Universitas Sumatera seekingrthodontics treatment with multiple spacing as the chief complaint. The comprehensive lateral cephalometry analysis showed class III skeletal malocclusion, concave profile skeletal trend, and abnormal dental inclination. There was also tongue thrusting in speech and swallowing based on functional examination. The initial orthodontic treatment was started by controlling the patient’s bad tongue habit along with orthodontic treatment. After seven-month of orthodontic treatment, this malocclusion was corrected and good interdigitation was achieved. Albeit there were no skeletal significant changes in this orthodontic treatment, the dental inclination showed a significant change based on cephalometry evaluation analysis. The success of the orthodontic treatment in the adult patient is not only dependent on proper mechanotherapy but also relied on the patient’s compliance with tongue habit control. Therefore, early bad oral habit detection as one of the etiologic factors in treating this malocclusion can support the success of orthodontic achievement.
Brooding Technology Use and Technical Efficiency among Egg Producers in Oyo State, Nigeria
Authors: O. Idiaye Chuks , F. Adebayo Adebusola , B. Oluwatayo Isaac
Published: October 2022

This paper investigated the types of brooding technology used by egg producers in Oyo State, Nigeria and its effect on technical efficiencies of the producers. The study was carried out in two Local Government Areas (LGAs) of Oyo State with data obtained from a total of 139 egg producers (farmers). Descriptive statistics was used to profile the farmers, probit model was employed to analyse the determinants of choice of brooding management technology, Cobb-Douglas stochastic frontier function was used to estimate technical efficiency among the farmers and Tobit regression model was also employed to ascertain technical efficiency determinants. The results show that only 9.4% of the farmers used modern brooding technology and over 50% of them employed unskilled labour. Sex of the farmer (p<0.10), household size (p<0.05) and having a secondary income (p<0.05) were the significant factors influencing adoption of modern brooding technology. Farmers who adopted the traditional brooding technology were found to be 4.3% more efficient than those using modern technology. Age (p<0.00), sex (p<0.05) and production experience (p<0.05) significantly affected their technical efficiencies. It was therefore recommended that technology subsidies, adequate extension training and skill acquisition be injected into the poultry industry to improve production efficiency.
Chemical Properties of Soil on Dry Land After The Eruption of Mount Sinabung in Kecamatan Payung, Karo
Authors: Marbun Christine , Jamilah  , Sarifuddin
Published: October 2022

This study aims to determine the chemical properties of soil on dry land after the eruption of Mount Sinabung in Kecamatan Payung, Kabupaten Karo. The eruption of Mount Sinabung that occurred from 2010 to 2020, released volcanic ash containing Silica, Aluminum, Sulfur, Magnesium, Sodium, Potassium, Calcium, Iron, Phosphate, and Manganese. Analysis of soil chemical properties was carried out at the Research and Technology Laboratory, Faculty of Agriculture, University of North Sumatra and PT. SOCFINDO. This study used 8 composite soil samples as research material, using survey methods and stratified sampling / grouping by overlaying several maps. Soil pH data analysis using electrometric method, C-organic content with Walkley and Black method, Cation Exchange Capacity (CEC) with NH4OAc extraction method pH 7, P2O5 ex-HCl, K2O ex-HCl, and Base Saturation (KB) with calculations (number of exchangeable base cations / CEC x 100%). The results of soil analysis showed that after the eruption of Mount Sinabung, dry land in Kecamatan Payung had acidic soil pH, high levels of P2O5 ex-HCl, levels of K2O ex-HCl with low to high criteria, levels of organic C tended to be high, soil CEC tended to be high and KB very low soil. Soil fertility status is included in the criteria of low and medium.
O BOLSONARISMO FRENTE À PANDEMIA DE COVID-19
Authors: Burgos Rafael , Santos de Oliveira Luma
Published: October 2022

Diante dos graves impactos causados pela pandemia da covid-19 no Brasil, o artigo busca elucidar os discursos do bolsonarismo sobre a morte, à luz de dois conceitos fundamentais: a pulsão suicidária e a negação do luto. No intuito de compreender os afetos que guiaram o presidente brasileiro na crise sanitária, exploramos o conceito de Estado suicidário, principalmente a partir das ponderações de Michel Foucault, e seus desenvolvimentos associados à pandemia no Brasil, conforme esmiúça Vladimir Safatle. Além disso, consideramos as ideias de Judith Butler a respeito do luto, a fim de pensar uma negação da vulnerabilidade frente à doença. Os resultados de nossa investigação buscam contribuir com as reflexões sobre como o bolsonarismo, e os fascismos de modo geral, lidam com a morte, e de que maneira, num contexto de crise sanitária e social, suas fantasias implicaram a produção de um morticínio em massa, acompanhado da negação de um luto coletivo.
O ENCARCERAMENTO DURANTE A PANDEMIA DA COVID-19
Authors: Costa Xavier Fernando César , Leão Encarnação Frederico Cesar
Published: October 2022

O artigo discute como o Poder Judiciário, mais propriamente o Superior Tribunal de Justiça e o Supremo Tribunal Federal, teriam legitimado um discurso de neutralização de indivíduos encarcerados (tornados um “outro”) no contexto da pandemia da Covid-19, ao julgarem casos em que deveriam aplicar e interpretar normas sobre medidas de contenção da propagação do vírus no ambiente prisional. A pesquisa é baseada em revisão bibliográfica e documental, no caso desta utilizando como fontes decisões judiciais e relatórios oficiais.
Autonomous Robotic Network to Resolve Coastal Oxygen Dynamics : Cruise No. AL547, 20.10. – 31.10.2020, Kiel – Kiel, ARCODYN
Authors: Sommer Stefan , Flögel Sascha , Walter Michael , Wenzhöfer Frank
Published: October 2022

The ALKOR cruise AL547 represents a concluding milestone of the Helmholtz innovation project ARCHES (Autonomous Robotic Networks to Help Modern Societies). The aim was to implement a heterogeneous robotic sensing network to simultaneously monitor changes in the water column and at the seafloor. The network has been developed by a consortium of partners from AWI, DLR, GEOMAR and the University of Kiel. The participating sensing platforms allow for real-time data transfer and the entire network shall be able to autonomously respond to environmental changes in the ocean. The network comprised seven different mobile and stationary platforms. Tests were conducted at the Mittelgrund working area in the entrance of the Eckernförde Bay (western Baltic Sea). During 47 stations the various sensing platforms were deployed and recovered for maintenance. A total of 87853 messages were sent using hydro-acoustics, of which 71734 messages contained O 2 data, 15177 were status messages, 926 messages were commands to trigger a change of the measurement behavior of a platform and 16 messages represented broadcasts about the environmental status. We synoptically recorded short-term O 2 time series on the different platforms, which were placed along a depth gradient in the working area. As the Eckernförde Bay is known for sporadic fish kills by anoxia we hope to contribute to a better understanding of the O 2 dynamics in coastal areas. - (ALKOR-Berichte ; AL547)
Pemilu dan COVID-19 di Indonesia (Partisipasi Pemilih dalam Pilkada Serentak 2020)
Authors: Ode Samsul , Dalupe Benediktus , Regif Surya Yudha , Jannah Dejehave Al
Published: October 2022

Peningkatan partisipasi dalam pilkada serentak 2020 di tengah bahaya Covid-19 merupakan kelanjutan dari pada tren partisipasi yang stabil dalam pemilu di Indonesia. Peningkatan ini bertolak belakang dengan kondisi demokrasi di Indonesia yang justru sedang memburuk. Peningkatan ini tidak dipengaruhi oleh kondisi perkembangan Covid-19 yang sesungguhnya. Peningkatan justru terjadi di daerah-daerah dengan jumlah kasus Covid-19 yang tinggi. Banyak penyelenggara pemilu dan kandidat dilaporkan telah terpapar virus. Membaiknya persepsi publik terhadap pelaksanaan pilkada dan kepercayaan pada pemerintah dalam penanganan pandemi mendukung meningkatnya partisipasi. Tetapi persepsi bukanlah penjelasan tunggal. Faktor-faktor yang menguat di tingkat lokal adalah penjelasan yang kuat untuk hal ini. Varian tingkat partisipasi yang berbeda-beda pada tiap daerah ditentukan oleh intensitas kompetisi dan isu politik lokal yang berkembang. Hal ini terkait erat dengan mobilisasi politik, karakter pemilih, dan maraknya politik uang. Riset ini menunjukkan gagalnya tesis linearitas partisipasi yang tinggi dengan tingkat kualitas demokrasi. Model perilaku pemilih juga gagal menjelaskan mengapa di saat kondisi ekonomi memburuk akibat pandemi, antusiasme pemilih justru meningkat.
FEATURES AND PLACE OF BUSINESS PARTNERSHIPS IN THE SYSTEM OF COMMERCIAL CORPORATE LEGAL ENTITIES
Authors: САХАРОВА Юлия Владимировна
Published: October 2022

Business partnership, as an organizational and legal form of legal entities, appeared in connection with an attempt to develop in Russia innovative venture activities similar to western organizations. However, due to the fact that this activity in Russia is not fully regulated and is risky, this form is unpopular, given that economic partnerships have general legal capacity and their legal status is not fully regulated. Having significant differences in the legal status of participants and the institution, organization and management, business partnerships are most similar to limited liability companies and economic fellowships. The similarity of business partnerships with limited liability companies is manifested in the same limit of the number of participants and the consequences of exceeding it, in the presence of a pre-emptive right to purchase the share of the participant in case of his exit. Business partnerships are similar to economic fellowships in the contractual model of functioning and in the fact that these organizations tend to «unite persons», where personal participation comes to the fore. They are also connected with each other by a legislative ban on the creation of organizations by one person. Purpose: to analyze the legal regulation of business partnerships and identify their distinctive features as a separate type of corporations, to compare them with other organizational and legal forms of legal entities. Methods: the method of interpretation and comparison, the system-structural method allows us to consider the object of the research in relation to other phenomena, as well as the method of system analysis. Results: in the system of corporate commercial organizations, a business partnership has a number of features of the composition of its participants and the order of establishment, organization and management of activities. The specifics of the legal status of participants in business partnerships are related to the requirement for them: the presence of other persons, the prohibition to be a participant or founder of a number of other legal entities, the procedure for the formation of the pooled capital.
Problems of legal regulation of the protection of genetic information obtained by methods of preimplantation and prenatal genetic diagnosis, In the Russian Federation
Authors: АХТЯМОВА Евгения Викторовна , АЛСЫНБАЕВА Эльвира Махаматовна , МАСАЛИМОВА Альбина Алмазовна
Published: October 2022

In the context of the active development of the areas defined by the Concept of Predictive, Preventive and Personalized Medicine, genodiagnostics, applied at the stage of family planning, is of particular importance. The introduction of preimplantation and prenatal genodiagnostics poses not only ethical but also legal problems. Of particular importance are the problems of protecting genetic information obtained using these methods from unauthorized use, which actualizes the need to improve the current regulatory framework for determining and specifying the conditions for carrying out such genodiagnostics. Purpose: to identify actual legal problems arising from the use of genetic information obtained by methods of preimplantation and prenatal genetic diagnosis, to determine the best ways of their solution as well as the main directions of further technological development and improvement of national legislation in the field of genetic diagnosis. Methods: the authors apply empirical methods of comparison, description, interpretation; theoretical methods of formal and dialectical logic; specific scientific methods: legal-dogmatic and interpretation of legal norms. Results: the analysis of the current legislation regulating preimplantation and prenatal genetic diagnosis in the Russian Federation reveals a number of pressing legal problems arising from the use of genetic information obtained in diagnostics. It is established that the current legislation does not take into account the specifics of genetic information and cannot provide effective protection against its illegal use in genetic diagnostics. General directions of improving national legislation in order to overcome problems related to the observance of human rights in the use of methods of preimplantation and prenatal genetic diagnostics are outlined.
THE PROBLEMS OF LEGAL REGULATION OF LEGAL LIABILITY FOR DAMAGE CAUSED BY THE OPERATION OF UNMANNED (AUTONOMOUS, HIGHLY AUTOMATED) VEHICLES
Authors: БЕРЕЗИНА Елена Александровна
Published: October 2022

The world community is currently at the stage of rapid development of all types of technologies – information, industrial, social, each of which, ideally, should be designed to improve various spheres of public life. However, any of the technologies carries certain risks that society and the legislator should take into account. One of the technologies gaining increasing popularity in many developed countries of the world is autonomous driving technology, which poses new challenges to legislators of all countries, forces them to solve new problems arising in connection with their introduction into public life. Such problems may include the problem of liability for damage caused by activities related to the operation of unmanned (autonomous, highly automated) vehicles. The pace of development of new technologies is constantly increasing, and the legislator does not always keep up with the development of social relations. In this situation, science should help to detect the problem and identify possible solutions. The purpose of the study is to analyze the problems of legal regulation of legal liability for damage caused by the operation of unmanned (autonomous, highly automated) vehicles. Methods: to achieve this goal, special legal methods are used: formal legal, based on knowledge of special legal terminology, legal constructions, classifications of legal phenomena; the method of interpretation of law used in the analysis of normative legal acts and their projects. Results: the conclusion is made about the need for a more balanced approach when legislating legal liability for damage caused by the operation of unmanned (autonomous, highly automated) vehicles. The author provides a justification for the need to classify highly automated vehicles (hereinafter referred to as HAV) and activities related to their operation to sources of increased danger, by analyzing the specifics of HAV; reveals the features of the composition of such a civil law tort as causing harm by the operation of HAV; indicates the grounds for civil liability for damage caused by the operation of HAV; designates the conditions and features of legal liability in the area under consideration. The article proposes as a priority for the Russian Federation to choose a concept according to which the subjects of legal liability for damage caused by the operation of the unmanned vehicle are both its owner and maker (manufacturer), who must bear joint responsibility regardless of the presence or absence of guilt.
Sexual aversion disorder: a case study, conceptualised and treated from a psychodynamic perspective
Authors: Caruso Norma
Published: October 2022

This article relies on psychoanalytic theory and technique to examine the dynamics of a couple with a sexual aversion disorder in one partner and to provide treatment. It uses the language of object relations, including Ogden’s (1989a,b) reformulation of Freud’s notions about the oedipal complex. In doing so, it defies the popular trend in sex therapy to employ behavioural methods, as well as the less commonly used approach to integrate psychoanalytic with behavioural techniques. The outcome supports the prospect of psychoanalytically oriented therapists reclaiming sexual difficulties as entities that are within the domain of their clinical expertise. Additionally, it adds to the literature on sexual desire disorders and because the partner, in this case, who presents with the sexual problem is male, it counters commonly held myths about male sexuality and recognises the complexity of their sexual functioning.
Comparative Study of in Situ Eswl vs Push Back, Stenting and Eswl for Non Obstructing Upper Ureteric Stone
Authors: Mozassem Ata M , Muhsin Syed Md , Billah KM Baki , Khan Shameema Hossain , Baki SM Nuruddin Abu Al , Hossain Mohammad Jahangir
Published: October 2022

Background : This is a hospital based prospective, cross sectional and interventional case control study conducted in department of urology, Chittagong Medical College, Bangladesh. Materials and methods : Total 120 patient of upper ureteric stone were included in this study divided by Group-A (60) and Group-B (60). Group-A 60 patient under went in situ ESWL and group-B 60 patient under went push back, DJ stenting and ESWL. Number of Shock wave session, energy used (KV) stone clearance, complications of ESWL like loin pain, haematuria, fever and Lower Urinary Tract Symptom (LUTS) and cost were compared between the two groups were recorded and analyzed. Results : In Group A total stone clearance were 96.7% (58/60) and group-B were 98.3% (59/60). But it was not statistically significant (p=0.559). Mean hospital stay of in situ group (Group A) was 1.03 ± 0.181 days compared to 2.57 ± 0.722 day in push back ESWL group (Group B). It was statistically highly significant (p=0.000). In group-A there was loin pain in 20 (33.33%). Haematuria 12(20%), fever in 06 (10%) and LUTS in 16 (26.7%) patients. In group B loin pain was in 35 (58.3%) (p-0.006). Haematuria 26(4.33%) (p=0.06), fever 14 (23.7%) (p=0.05) LUTS was 30 (50%) (p=0.009). More energy of ESWL (Kilo Volt-KV) required in group A than in group B. But is was not statistically significant (p=0.190). Conclusion : Complications between the groups were statistically highly significant. In situ ESWL is very good option for the management of upper ureteric stone. It is non-invasive, effective, safe, cost savings, less hospital stay and usually does not need anaesthesia.

JCMCTA 2017 ; 28 (1) : 57 - 62
PENGARUH TEKNIK VIDEO EDUKASI TERHADAP PERILAKU BULLYING SECARA VERBAL PADA SISWA DI YAYASAN PEDULI ANAK
Authors: Najamuddin M.
Published: October 2022

Semakin berkembangnya zaman perilaku siswa khususnya para remaja saat ini menunjukkan perilaku negatif pada orang tua dan pada temannya sendiri. Apalagi dengan adanya handphone membuat perilaku remaja saat ini minim atitude, karena mereka bisa menonton video dengan bebas dan meniru peran didalam video tersebut baik peran yang positif maupun yang negatif. Rumusan masalah dalam penelitian ini apakah ada pengaruh teknik video edukasi terhadap perilaku bullying secara verbal? pada siswa SMP kelas VIII di Yayasan peduli Anak tahun pelajaran 2021/2022. Tujuan dalam penelitian ini adalah untuk mengetahui pengaruh teknik video edukasi terhadap perilaku bullying secara verbal pada siswa SMP Kelas VIII Di Yayasan Peduli Anak Tahun Pelajaran 2021/2022. Metode dalam penelitian ini adalah menggunakan rancangan one group pre-test dan post-test design. Populasinya yaitu ada 19 siswa dan 6 siswa memiliki perilaku bullying tergolong tinggi. Teknik pengumpulan data menggunakan angket, sedangkan observasi, wawancara, dan dokumentasi sebagai metode pelengkap. Berdasarkan hasil analisis data menggunakan rumus t-test, yakni 4,085 dan setelah dicocokkan dengan nilai ttabel pada taraf signifikansi 5% dengan (N-1)=(6-1)=5 sebesar, 2,571. Dengan demikian nilai t hitung lebih besar daripada nilai ttabel (4,085>2,571), sehingga dapat disimpulkan ada pengaruh teknik video edukasi terhadap perilaku bullying pada siswa SMP kelas VIII di Yayasan peduli Anak Tahun Pelajaran 2021/2022, maka hasil penelitian ini dapat dinyatakan signifikan.
The Proposal of Gamma Folded-Normal Distribution
Authors: ALTİNİSİK Yasin , CEYLAN Tahir , ÇANKAYA Emel
Published: October 2022

Development of new flexible distributions for modeling non-negative measurements occuring in lifetime or reliability studies is a prominent research area in Statistics. As being the most favoured positive definite form, the Gamma distribution poses a basis for such improvements. It is well known that transforming a Gamma variable with another continuous random variable (X) creates Gamma-X family of distributions. Following this principle, we here attempted to define the X variable as Folded-Normal distributed which is also positive definite so as to propose a new family of distributions. Named as Gamma Folded-Normal distribution (GFN), our proposal is a generalization of Gamma Half-Normal distribution and contains more freely estimated parameters. This study evaluates some mathematical properties of GFN distribution such as moments and illustrates the estimation procedure for unknown parameters through a simulation study. A separate simulation is also conducted to compare the performance of this new distribution with the Folded-Normal, Half-Normal and Gamma Half-Normal distributions. Besides, the practical importance of our new proposal is illustrated by analyzing a real world data set.
New Paradigms in Heart Failure: RAAS Inhibition and the Management of Hyperkalaemia
Authors: Smithers Lucy
Published: October 2022

This educational symposium discussed advances in blocking the renin–angiotensin–aldosterone system (RAAS) for patients with chronic systolic heart failure (HF), and the issues of managing hyperkalaemia in these patients.

Prof John McMurray introduced the session, outlining the current treatment paradigm and the challenges presented by the associated risks of hyperkalaemia. Prof Faiez Zannad discussed the under-utilisation of life-saving RAAS inhibitor (RAASi) drugs in clinical practice and the benefits to be gained for patients by optimising their use. Prof Ileana Piña reviewed current advances in pharmacological treatments for chronic HF that aim to reduce the risks of renal dysfunction and hyperkalaemia. Finally, Prof John McMurray discussed the potential of new treatment paradigms for improved outcomes in patients with chronic HF.
Clinical Trials for the Diagnosis and Management of Stable Ischaemic Heart Disease: Context, Status, and Future Implications
Authors: Corcoran David , Mangion Kenneth , Berry Colin
Published: October 2022

Chest pain and coronary artery disease (CAD) impose a substantial burden on public health and society. Diagnostic imaging tests are used by clinicians to identify the presence and extent of epicardial coronary disease and/or its consequences, including ischaemia, infarction, and left ventricular dysfunction.

In this article, we discuss current practice guideline recommendations for the diagnosis and management of patients with suspected or known CAD, and the need for more evidence from clinical trials. We then focus on the recently published and ongoing multicentre clinical trials of imaging-based strategies for the diagnosis and management of ischaemic heart disease, and the potential future impact of these trials on clinical practice. The results of these trials have the potential to bring radical changes to the practice of cardiology in the future.
When the Going Gets Tough, the Tough Get Going
Authors: Rodríguez de Ledesma Ana
Published: October 2022

Patients with elevated blood pressure (BP) represent a major problem for primary care physicians, not only because of the large number of these patients, but also because BP can prove frustratingly difficult to control in some of them. The management of treatment-resistant hypertension (TRH) is indeed a topic of considerable interest over the last few years, particularly since novel, non-pharmacological interventions held out the prospect of helping these patients. The theme of this mini-symposium was how currently available therapeutic tools can be used to manage ‘difficult-to-control’ patients with persistently elevated BP who may have apparent treatment resistance.

To ensure that this symposium was relevant and practical, invited experts used a patient case in which treatment fails to control BP. One option in such a case might be to assume that the patient has apparent TRH. However, by looking at the case in more detail and carrying out a thorough clinical work-up, other factors such as pseudo-resistance or poor adherence might be playing important roles. The case was used to highlight the importance of investigating the reasons behind a patient’s failure to achieve BP control and the steps that can be taken to address these issues.

Professor Josep Redòn introduced the clinical case and discussed the selection of appropriate management strategies and therapies. Estimation of the risk, based on the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC) treatment guidelines, and details of the ongoing difficulties in reducing the patient’s elevated BP were also covered during his presentation. Professor Michel Burnier discussed in detail difficult-to-control BP and the need for clinical assessment. Among the topics covered were the patient’s referral to a specialist treatment centre, apparent resistance to modification/intensification of treatment, detailed investigation to rule out spurious resistant hypertension, assessment of treatment adherence, and development of a plan or management strategy to educate and motivate the patient and improve adherence to treatment. Professor Massimo Volpe discussed the ongoing management of difficult-to-control patients using strategies designed to favour adherence, including single-pill, fixed-dose combination (FDC) therapy. The meeting was concluded with an interactive discussion, in which the audience raised issues arising from the case presented; these included poor adherence, spurious TRH as a misdiagnosis, and the need for a thorough clinical assessment in order to identify the true cause of the failure to control BP.
Musical Politics in the Cuban Police Order
Authors: Bøhler Kjetil Klette
Published: October 2022

Kjetil Klette Bøhler considers how interlocking grooves and call–response patterns in contemporary Cuban music generate new forms of political engagement, which he analyses alongside a close reading of the context within which musician Roberto Caracass s enacted a Rancièrean ‘wrong’ by claiming a voice within a police logic that denied him one.
Rancière’s Affective Impropriety
Authors: Stover Chris
Published: October 2022

Chris Stover stages three moments in jazz history as dis-identificatory practices that resist folding back into new police logics. In this way he interrogates what happens after the event of the dissensual moment and theorizing the ways in which new distributions of the sensible are formed and how new police actions are effected from within a community. Stover offers an alternative means of disrupting the speech/ noise dichotomy: not the political insistence that what was heard as noise now be heard as speech, but that noise itself can carry political meaning in the aesthetic regime.
Towards a Yoruba Indigenous Model of Communication for Software Development in Digital Humanities
Authors: Akin-Otiko Paul Akinmayowa , Farinola Augustine Akintunde
Published: October 2022

Drawing insight from Toyin Falola’s call for African scholars to Africanize knowledge, this article argues for reviewing the digital technological tools used for African Studies research to process and present African data properly. To achieve this, the inadequacies of digital humanities (DH) for specific areas of African Studies will be highlighted, especially in the deployment of digital humanities tools. The major challenge is the distortion and constraint experienced in processing and presenting research through DH means of translation and communication. The article argues that such technological limitation has its root in the incompatibility of the epistemological frameworks within which those digital tools were developed. The article discusses Ojú lòrówà (‘discussion is in the eye’), that is, ‘communication takes place when we see physically’ – a theory of communication in African society used as a model to highlight the importance of African context to African scholars in their exploration of African history, technology, culture, philosophy and tradition. The indigenous theory is an appropriate model for developing digital and virtual software for African scholars in human communication. The article concludes by urging scholars in African Studies to ensure that the digital tools employed in African Studies can collect data and process and present data adequately without losing the original meaning or sense.
Upgrading of a Technique for Visual Comparing for the Results of Azimuthal Magnetotelluric Monitoring with the Seismic Events Parameters
Authors: Nepeina K. S. , Matiukov V. E.
Published: October 2022

The paper presents a practical implementation of the task of visualizing additional geophysical information for analyzing the results of azimuthal magnetotelluric (MT) monitoring. Since some patterns of a sharp change in the sign of relative apparent resistivity variations (Δρ) for MT monitoring points depending on ongoing seismic events, as well as lunar-solar tides, were found in previous studies, it became necessary to give illustrative examples proving such cases. For this, we propose to improve the technique for constructing additional graphs containing such parameters of seismic events as: source depth, distance between the source and the observation point, azimuth and energy class, in accordance with the observation time. All parameters are obtained from published seismic catalogs. A method for displaying pseudosections Δρ, combined with a hypocenter distribution plot, in Surfer program is shown. An example of a graph containing simultaneously information about the distance and azimuth of the event relative to the monitoring point, in the form of rotated arrows, is given. Such graphical constructions are maximally automated, and allow the interpreter to confirm the arguments in favor of the spatial-temporal dependence of the variations of electromagnetic parameters on the events occurring in the observed earth's interior.
Aftershocks of the strongest earthquakes in Asia in zones of different seismicity levels
Authors: Kuchay O. A.
Published: October 2022

The average values of seismic activity obtained from the aftershock sequences of the strongest earthquakes in Asia (M>6.9) are not correlated with the levels of background seismicity in the areas of the strongest events and their magnitudes. A high level of seismic activity is manifested in zones of large active faults and is reflected in aftershock sequences.
Solution of an inverse dynamical seismic problem on the base of a deep convolutional neural network
Authors: Bratchikiov D. S. , Gadylshin K. G.
Published: October 2022

The paper presents an original approach to solving the inverse dynamical seismic problem for the scalar wave equation in seismic monitoring. Instead of using the expensive full waveform inversion method, it is proposed to approximate the inverse problem operator, which translates the difference in the data into the models' perturbation, using a deep convolutional neural network of the Unet type architecture. The operability of this approach was demonstrated on a simple test example.
Uncertainty quantification of phase velocity surface waves multy-modal inversion using machine learning
Authors: Yablokov A. V. , Serdyukov A. S.
Published: October 2022

The paper is devoted to uncertainty quantification of the inverse problem solution of the multichannel analysis of surface waves method - the inversion of the curves of the phase velocity via frequency dependence. The uncertainty estimation approach is based on the Monte Carlo sampling strategy and a multilayer fully connected artificial neural network to approximate nonlinear dependence of shear wave velocity and layers thickness via values of phase velocity surface waves. Frequency-dependent noise in the data and errors of the inverse operator are projected onto the inverse problem solution. The results of unimodal and multimodal inversion are compared on the example of synthetic data processing. The experimental results show that using of machine learning approaches makes it possible to quickly and accurately estimate the posterior probability density of the reconstructed velocity model parameters.
Detection of Manifestations of Induced Polarization in Induction Transient Processes when Working with Coaxial Loops
Authors: Antonov E. Yu. , Kozhevnikov N. O. , Korsakov M. A.
Published: October 2022

Methods for differentiating large data arrays, obtained as a result of areal soundings by the transient electromagnetics method, are discussed, in order to find regions, with varying degrees of manifestations in the signal of induction-induced polarization or its absence.
Application of the method of electrotomography to control the filtration experiment on core samples
Authors: Yurkevich N. V. , Anchugov A. V. , Kucher D. O.
Published: October 2022

The work considers application of the method of electrotomography during the experiment on oil displacement from core samples to determine the current water and oil saturation of the samples.The implementation of this method in reservoir conditions in terms of pressure is considered. A map of the 3-dimensional distribution of electrical resistivities and current water saturation of core samples is constructed during the displacement experiment using the inversion of apparent resistances obtained by measuring potentials from a current source on the sample surface. The possibilities of the method for monitoring the course of various experiments are discussed.
Relationship of the parameters of physico-chemical and sorp-tion processes with the emission of coal beds. part I: on the influence of physical and chemical parameters of natural coals on their metane capacity
Authors: Kiryaeva T. A.
Published: October 2022

This part of the article shows shows that methane capacity is closely related to the physicochemical properties of coals and the physical structure of coal matter: porosity, moisture, ash content, petrographic composition and the release of volatile substances. It was found that the porosity of natural coals weakly depends on the stages of metamorphism and its effect on the methane content of coals can be ignored. Based on the catalogs of the physicochemical properties of coals from the developed deposits of Kuzbass, it is shown that differences in ash content and moisture content of coals have very little effect on their me-thane capacity, and the main strongest influencing factors on the methane capacity of coal were the depth of coal seams and the release of volatiles.
Application of computational modeling to study the parameters of dusty air flows in subway
Authors: Lugin I. V. , Kiyanitsa L. A. , Oshchepkov T. S.
Published: October 2022

To date, the subway is the most promising type of urban public transport, which is used daily by thousands of passengers in the world. In modern subways, the problem is the content of suspended dust in the air, which exceeds the maximum permissible concentration. Especially dangerous is the dust fraction PM2.5 or less, capable of penetrating through the biological barriers of the human body. This article discusses the results of a number of studies aimed at determining the concentration, fractional and chemical composition of such dust in subway structures. One of the ways to combat dustiness of the air in subways is its filtration. The authors propose the use of filters installed in the jetty ventilation breakdowns, the air flow through which is provided by the piston action of trains. Determination of optimal design and operational parameters of such filters is carried out using computer modeling by the finite volume method. The article provides an overview of the existing computational mathematical models of the movement of dusty air as a multiphase flow, and considers the possibility of their application to the conditions of underground subway structures.
Investigation of aerodynamic schemes of reversible mine fans
Authors: Kosykh P. V. , Krasyuk A. M.
Published: October 2022

The article considers the aerodynamic scheme of the main ventilation fan with high aerodynamic properties in reverse operation mode based on the use of a rotating input guide vanes. The dependences of the setup angles of the blades of the input guide vanes and the rotor, when the fan is switched to the reverse mode, on the required flow coefficients and fan pressure at certain parameters of the profile cascades at a mean radius are revealed. Using the example of the designed aerodynamic schemes, the influence of the swirl of the flow in the guide device, the solidity of the blade cascades of the rotors and the torsion of the blades on the aerodynamic characteristics of the reversible fan operation mode, calculated in the ANSYS CFX, is shown. Obtained fan aerodynamic scheme provides a performance in the reverse mode operation equal to 0.96 of the performance of the direct mode in the same ventilation network.
Automation and robotization of solid mineral mining
Authors: Tishchenko I. V. , Vanag Yu. V.
Published: October 2022

Improvement in competitiveness of mining clusters is inextricably linked with enhancement of labor safety and efficiency. Meeting these objectives is possible through wider implementation of robotic systems both at the stages of mining and transportation of minerals. The paper analyzes the current state, prospects and a general trend of development of robotic mining equipment. The advanced types of foreign and Russian automated equipment, and also the basic concepts and programs of robotization are considered. To date the areas of application of robotics in the mining industry include automated batching, rock excavation and transportation, mapping and geodesy, drilling and explosives processing. The introduction of robots in mining places special demands on their reliability and quality, and raises numerous problems and unresolved issues that both academia and industry must jointly identify and address. The widespread use of robotic technology in surface and underground mining can lead to significant changes in the design of quarries and mines, as well as in the safety regulations, and contribute to the development of new types of mining machinery and equipment, which will provide a significant increase in mining efficiency.
Gambaran Tingkat Kelelahan Kerja Berdasarkan Karakteristik Pada Supir di PT Martadinata Indah Tambang Alindau Kabupaten Donggala
Authors: Sunuh Herlina
Published: October 2022

Pendahuluan: Hasil survey yang pernah dilakukan di negara maju dilaporkan bahwa kelelahan yang dialami penduduk sebesar 10-50%. Data ILO disebutkan bahwa sebanyak dua juta pekerja meninggal dunia hampir setiap tahun akibat kecelakaan oleh faktor kelelahan. Tujuan: Penelitian ini bertujuan ingin mengetahui gambaran kelelahan kerja supir dump truck dilihat dari segi karakteristik. Metode: Jenis penelitian ini merupakan penelitian deskriptif dengan menggunakan pendekatan observasional. Lokasi penelitian dilakukan di PT Martadinata Indah Tambang yang berlokasi di di Desa Alindau kecamatan Sindue Tobata Kabupaten Donggala. Waktu penelitian dilakukan pada tanggal 1-25  Agustus 2020. Populasi dalam penelitian ini adalah supir dump truck yang mengangkut material tambang sejumlah 30 orang. Hasil: Hasil menunjukkan bahwa sebanyak 18 orang mengalami tingkat kelelahan sedang dan berada pada umur kurang dari 44 tahun, serta mereka dengan waktu kerja semuanya  kurang dari 8 jam perhari, 15 orang diantaranya dengan status gizi yang normal. Kesimpulan: Kesimpulan dari penelitian ini adalah 10 orang mengalami kelelahan berat, yang berada pada umur ≥ 40 tahun, semua supir bekerja dengan waktu setiap harinya kurang dari 8 jam, 4 orang diantaranya mempunyai status gizi gemuk serta 5 obesitas.
Gambaran Kebisingan dan Keluhan Masyarakat di Sekitar PT. Martadinata Indah Tambang Alindau Kabupaten Donggala
Authors: Sasmita Hanum , Sapriana Sapriana , Hasanudin Hasanudin , Agustina Eli
Published: October 2022

Latar Belakang: Kebisingan dapat menimbulkan dampak yang membahayakan kesehatan pekerja maupun masyarakat. Beberapa keluhan yang sering dirasakan oleh pekerja dan masyarakat karena bising diantaranya: sulit konsentrasi, gangguan pendengaran, hipertensi, gangguan tidur, dan lelah. Tujuan: Penelitian ini bertujuan mengetahui gambaran kebisingan dan keluhan masyarakat disekitar PT. Martadinata Indah Tambang Alindau. Metode: Penelitian ini merupakan penelitian deskriptif. Data variabel keluhan/gangguan dikumpulkan dengan wawancara dan data variabel kebisingan dikumpulkan dengan pengukuran. Jumlah populasi 42 orang atau seluruh masyarakat yang tinggal disekitar perusahaan, sampel adalah total populasi. Teknik sampling menggunakan metode Accidental Sampling,  sehingga pada titik terdekat sampel sebanyak 14 orang, titik tengah 15 orang dan titik terjauh 13 orang. Titik pengukuran kebisingan terdiri dari tiga titik, yakni titik terdekat (97m), tengah(150m) dan terjauh (300m). Adapun instrumen penelitian berupa kuesioner, dan sound level meter. Data dianalisis dengan cara deskriptif dan disajikan dalam bentuk tabel distribusi frekuensi. Hasil: Hasil analisis menunjukkan kebisingan pada titik terdekat rata-rata adalah 83,4 dB(A) dan semua (14 responden) mengalami keluhan/gangguan, pada titik tengah rata-rata adalah 76,9 dB(A) dan semua (15 responden) mengalami keluhan/gangguan, dan titik terjauh rata-rata adalah 56,6 dB(A) dan semua (13 responden) tidak mengalami keluhan. Kesimpulan: Semakin dekat dari sumber kebisingan, keluhan semakin dirasakan oleh masyakat. Sebaiknya dilakukan upaya untuk meminimalisir kebisingan misalnya dengan melakukan pengawasan tingkat bising, dan membuat barrier.
Pengaruh Ketebalan Media Saringan Pasir Lambat terhadap Penurunan Kekeruhan dan Warna Air Permukaan Menggunakan Sistem Down Flow
Authors: Nuradjie Sugeng , Sampo Sercyana
Published: October 2022

Pendahuluan: Air permukaan berwarna dan keruh terlalu tinggi dapat menyebabkan permasalahan  dan beresiko terhadap kesehatan masyarakat. Salah satu cara penurunan kekeruhan dan warna air  menggunakan Saringsn Pasir Lambat (SSF). Tujuan: Tujuan penelitian diketahuinya pengaruh variasi ketebalan media SSF down flow terhadap penurunan kekeruhan dan warna air permukaan. Metode: Jenis penelitian ini eksperimen dengan pendekatan pre-test and post-test serta kontrol. Eksperimennya  menggunakan empat variasi ketebalan SSF dan satu kontrol.  Total sampel perlakuan 24 sampel dan 6 pretest. Kapasitas air filtrasi 7 liter/m2 menit dengan sistem down flow. Cara sampling perlakuan dan kontrol dilaksanakan secara random dengan interval waktu 15 menit setiap perlakuan. Hasil: Berdasarkan hasil uji statistik  terdapat pengaruh signifikan (dengan taraf p < 0,05) ketebalan media SSF terhadap penurunan tingkat kekeruhan dan warna dalam air permukaan. SSF sistem down flow dapat menurunkan kekeruhan air 92,57 % - 94,36 %. Penurunan kekeruhan air  tertinggi di level 94,36 % pada media pasir 100 cm,  sedangkan penurunan warna air   antara 86,31 %-95,36 %, dan  penurunan  warna tertinggi sebesar 95,36 % pada media 100 cm. Kesimpulan: Ada pengaruh ketebalan media pasir terhadap penurunan  kekeruhan air permukaan dan penurunan warna  air permukaan.