bluuebunny/crossref_metadata_2025 huggingface dataset:
Valorización de Residuos Mineros como Áridos para la Construcción de Carreteras: Economía Circular en la Región Andina del Perú
Authors: Torres Gonzales Yovana , Gonzales Cabrera Raquel , Cotera Nuñez Isaac Abraham , Arana Ruedas Del Piero Raphael
Published: May 2024

La minería en el Perú es la mas grande actividad económica aportando un porcentaje considerable al Producto Bruto Interno nacional. Sin embargo, el proceso de esta actividad evidencia diversos conflictos socio-ambientales. La generación de residuos mineros o expresados como relaves mineros provenientes de los diversos procesos es una amenaza latente que afecta las esferas del desarrollo sostenible. Este estudio tuvo como objetivo la propuesta de valorización de relaves mineros como áridos para la construcción de carreteras en la región andina del Perú bajo un enfoque de economía circular. En consecuencia, se realizó diversos análisis para evaluar su viabilidad como el factor meteorológico de precipitación, acidez o alcalinidad, elementos presentes en la muestra, granulometría, California Bearing Ratio (CBR) y prueba Marshall. Los resultados han demostrado que la propuesta cumple con los parámetros establecidos a nivel nacional con una estabilidad de 877,67 kg y un aprovechamiento del 25% de los relaves mineros. En conclusión, el uso de relaves mineros como áridos para la construcción es una propuesta viable para la construcción de carreteras bajo un enfoque de economía circular. Finalmente, se recomienda el análisis de valorización de residuos mineros en otros elementos del sector construcción para continuar promoviendo la economía circular y desarrollo sostenible.
Implicancias del modelo industria 4.0 en la agroindustria: Revisión sistemática
Authors: Chagua-Rodríguez Perfecto , Chañi-Paucar Larry Oscar , Malpartida-Yapias Rafael Julián , Javier-Ninahuaman Henry Juan , Luciano-Alipio Rober Anibal , Salvador-Reyes Rebeca
Published: May 2024

El modelo de economía circular propone una serie de componentes tecnológicos digitales, que son facilitadores claves para la eficiente y sostenible producción de bienes y servicios. Sin embargo, las aplicaciones de este modelo en el sector agroindustrial permanecen en investigaciones progresivas, en algunos casos con limitados estudios en esta área. La metodología empleada siguió los procedimientos de una revisión sistemática de literatura, bajo el enfoque PRISMA. El principal objetivo de la presente revisión es proporcionar una descripción general de las aplicaciones del modelo de economía circular, incidiendo en la introducción y uso de la robótica, sensores inteligentes, técnicas de procesamiento emergente, inteligencia artificial, big data y el internet de las cosas en el sector agroindustrial y agroalimentario. El modelo Industria 4.0, plantea al sector industrial la incorporación de la robótica y otros dispositivos inteligentes para desarrollar procesos automatizados, que permitan mejorar la toma de decisiones y afrontar los cambios y exigencias del mercado. Entre de los principales hallazgos de nuestra exploración se destaca el incremento de estudios sobre inteligencia artificial, tecnología robótica emergente, sensores y softwares avanzados, que se combinan para contribuir a la solución de problemas del sector manufacturero, específicamente en los procesos pre y post productivos, en la gestión de la cadena de suministro y la obtención de productos que demanda el consumidor de estos tiempos. Finalmente, la revisión examina las consideraciones actuales e identifica las principales brechas para el desarrollo de futuras investigaciones.
Respuesta de pastizales naturales degradados a la revegetación y la aplicación de estiércol de ovino
Authors: Mamani Paredes Javier , Terroba Nicaela , Quispe Merma Javier , Supo Halanoca Felix
Published: May 2024

Los pastizales naturales son importantes para la producción ganadera, son fuente de alimentación principalmente para el ganado rumiante. El estudio se realizó en pajonales del altiplano de Puno Perú a una altitud de 3818 msnm el objetivo fue determinar el efecto de la revegetación con dos gramíneas nativas: Festuca dolichophylla Presl “chilligua” (Fedo) y Poa gilgiana Pilger “K´achu” (Pogi) en la recuperación de pastizales degradados con adición de estiércol de ovino como fuente de materia orgánica (MO), conducido bajo el diseño de parcelas divididas cuyos factores de estudio fueron 2 especies nativas, 2 factores de abonamiento con y sin adición de (MO) heces y orina de ovino, en 3 bloques; los resultados indican que el mayor crecimiento y rendimiento de biomasa fue para Fedo probablemente por su capacidad de adaptación, rendimiento de materia verde de Fedo y Pogi fue superior en el tratamiento con adición de MO, la incorporación de estiércol al pastizal influyo positivamente en la recuperación del pasto, por otra parte Fedo resulto con mayor altura que Pogi;; la producción de semilla de los tratamientos adicionados con MO fueron superiores a los tratamientos sin aporte de MO; el contenido de proteína con adición de MO fue mayor en ambas especies, la FDN fue mayor en las especies sin adición de MO, la aplicación de MO favoreció el crecimiento y el valor nutritivo de las especies. Se concluye que la revegetación e incorporación de estiércol de ovino tuvo un efecto favorable en la recuperación y calidad nutritiva del pastizal.
Assanhando o formigueiro: a inserção em organização política no processo formativo de residentes em saúde de Pernambuco
Authors: Pessôa Anna , Oliveira Vick Brito
Published: May 2024

Ao passo que a dimensão política se mostra importante na formação de profissionais de saúde para o Sistema Único de Saúde (SUS) enquanto política pública, os espaços de organização política e social de residentes em saúde são considerados estratégicos para a formação desses/as trabalhadores/as. Essa pesquisa objetivou compreender como a inserção no Coletivo Pernambucano de Residentes em Saúde repercute na formação e prática profissional de egressos de programas de residência em saúde. Foi realizada uma pesquisa qualitativa através de entrevistas semiestruturadas com egressos que atuam no SUS. Os resultados apontam, principalmente, repercussões nos campos da formação política, atuação profissional, controle social e construção do sujeito político residente. Nesse sentido, a pesquisa reforça a importância da inserção dos residentes em espaços políticos, na defesa do reconhecimento e inserção desses espaços no currículo formal dos programas de residência.
 
Palavras-chave: Internato e Residências; Educação Continuada; Participação Social; Política de Saúde.
Saúde mental de mulheres trans em situação carcerária no estado do Pará
Authors: Carneiro da Silva Alessandro , Campos Alvarenga Eric
Published: May 2024

Há uma precariedade na saúde mental de mulheres trans na realidade prisional brasileira, especialmente no Pará, quando comparada à comunidade em geral, em situação de cárcere ou não. Este trabalho visa analisar os impactos na saúde mental de mulheres trans ex-apenadas, com base em relatos sobre suas vivências de encarceramento em presídios do estado do Pará. Trata-se de um estudo qualitativo e descritivo, que realizou entrevistas semiestruturadas com duas mulheres trans do estado do Pará que vivenciaram pelo menos um mês de cárcere. O material produzido nas entrevistas foi analisado por meio da técnica de análise de conteúdo. Como resultado, é possível observar que as mulheres trans não são vistas como dignas de atenção e cuidado pelos agentes institucionais responsáveis por sua detenção durante o processo de aprisionamento, do que impede a garantia de assistência que as acolha em suas necessidades básicas e particularidades. A desvalorização, desqualificação e o processo de subjetivação são amplamente disseminados e praticados por meio do cis-heterocentrismo e cis-heteroideologia, tornando-se fundamental discutir e compreender os processos de experienciações da camada da população trans que vive em situação de cárcere, abordando as violências que ocorrem nesse ambiente e analisando os impactos gerados em sua saúde mental. Logo, nesse percalço, essa política de encarceramento apresenta-se como ineficiente, o que é algo negativo, uma vez que é obrigação do Estado, garantido nos registros da Constituição Federal e em documentos protetivos internacionais.
 
Palavras-chave: Mulheres trans; Sistema Carcerário; Saúde Mental.
A determinação social da saúde em assentamentos rurais: aspectos sobre o trabalho e a saúde de camponeses criadores de bovinos, caprinos e ovinos
Authors: Barbosa Junior Sebastião André , Lira Paulo Victor Rodrigues de Azevedo , Albuquerque Pedro Costa Cavalcanti , Gurgel Idê Gomes Dantas , Oliveira Jaqueline Bianque , Freitas Aderaldo Alexandrino , Rizzo Huber
Published: May 2024

O objetivo da pesquisa foi analisar os aspectos do trabalho e da saúde de camponeses criadores de bovinos, caprinos e ovinos com base na determinação social da saúde. A pesquisa foi realizada em cinco assentamentos rurais no estado de Pernambuco, utilizando-se a entrevista estruturada e técnicas do diagnóstico rural participativo. A maioria dos camponeses eram do sexo masculino, com média de idade de 52,3 anos e baixa escolaridade. A renda familiar em 91,4% dos camponeses foi de um até três salários-mínimos. O trabalho com os ruminantes era realizado em sua maioria pelos homens. Os principais equipamentos de proteção individual utilizados foram: bota de borracha, chapéu e o protetor solar. Poucos camponeses (10,6%) tinham brete em suas criações. Foi observado que 25,5% dos camponeses relataram algum tipo de acidente de trabalho, 78,7% utilizavam agrotóxicos e o trabalho com os animais foi classificado como árduo. Apenas o assentamento Serra Grande contava com uma Unidade Básica de Saúde, e as principais doenças relatadas foram: Doenças Osteoarticulares Relacionadas ao Trabalho, hipertensão arterial, arboviroses, diabetes e esquistossomose mansoni. O trabalho dos camponeses com as criações de ruminantes é determinado socialmente pelo agronegócio e se mostrou desgastante, associado com a ausência e condições precárias dos serviços de saúde.
 
Palavras-chave: Acidentes de Trabalho; Agricultura Sustentável; Animais de Produção; Política de Saúde; Saúde da População Rural.
The Potential of Hydroxyapatite-Alumina Composites for Artificial Bone Implant
Authors: Yetri Yuli ,   Department of Mechanical Engineering, Politeknik Negeri Padang, Limau Manis, Padang, 25166, West Sumatera, Indonesia, Ikhsan Ikhsan , Affi Jon , Gunawarman Gunawarman , Asmara Yuli Panca ,   Department of Mechanical Engineering, Politeknik Negeri Padang, Limau Manis, Padang, 25166, West Sumatera, Indonesia,   Department of Mechanical Engineering, Universitas Andalas, Limau Manis, Padang 25166, West Sumatera, Indonesia,   Department of Mechanical Engineering, Universitas Andalas, Limau Manis, Padang 25166, West Sumatera, Indonesia,   INTI International University, Faculty of Engineering and Quantity Surveying, Negeri Sembilan, 71800, Malaysi
Published: May 2024

The production of hydroxyapatite (HA) from bovine bone has been carried out, to which alumina (Al2O3) and ortho resin will be added to form HA-alumina composites. The aim of this research is to obtain HA-Alumina composites which can be used as artificial implants. Bovine bone waste was synthesized by mechanical thermal. Its charaterization was performed by means of X-Ray Fluorescene (XRF) for ratio (Ca:P) analysis, Scanning Electron Microscopy (SEM) for microstructure, X-Ray Diffraction (XRD) to analyze the crystals of HA, Electron Diffraction X-Ray (EDX) was utilized to measure the composition of HA-alumina composites. The mechanical method with calcination at a temperature of 800oC was conducted on bovine bones to obtain HA. The HA-alumina composite was continued with the addition of 0%, 15%, 25%, and 50% of the total weight of alumina by adding resin as a binder. Analysis with SEM showed irregular round grains with an average size of 42.25μm. The obtained XRF analysis result was a Ca/P ratio of 1.61. The hardness and tensile strength of the composite increased and the percentage of agglomeration area decreased as the alumina composition was added. The addition of 50% alumina resulted in maximum hardness and tensile strength values of 124.8 HB and 86.56 MPa. The addition of alumina increased the mechanical properties of hardness and tensile strength. Hence, HA-Alumina composites could be used as artificial bone implants.
Characterizing the Relationship Between Sputtered Atom Flux Generated by Electrical Discharge in Plasma and Thin Film Deposition Quality
Authors: Bouazza Abdelkader ,   L2GEGI Laboratory, University of Tiaret, 14000 Tiaret, Algeria
Published: May 2024

Thin film technology is still under development, to comply with industrial demands it is necessary to be able to produce a high quality thin film, to accomplish this we must know the several parameters which contribute to the disposition of the ejected particles, on this work we have presented the analysis of semiconductor atom deposition on magnetron sputtering in 3D curves, using SIMTRA software we created a vacuum chamber which has dimension of 25cm×25cm×40cm, the magnetron used has a circle shape target with a radius of 4cm which contains two different target ( Si and Ge) and the substrate has a 10cmx10cm rectangle shape, after this adjustments with the use of Monte Carlo code we simulated the particle ejected away from target to find the number of collisions and the number of atoms arrived on the substrate with a variation of the distance that the atoms ejected had to cross, a very clear result was found which will show you that widening the distance negatively affects the coating and the deposition of the atoms.
Relevance of Hasan al-Banna’s Viewpoint on Islamic Education through Nizam al-Usrah on Character Building
Authors: Alam Naufal Ahmad Rijalul , Hamid Nur Bakri Abd
Published: May 2024

Technology advancements are acknowledged to make it simpler for young learners to access information and knowledge, but they also lead to a change in values in people's outlook on life and their religious practices due to a leaning towards freedom and hyper technology. Islamic education must act in response to these circumstances by implementing a number of tactical measures to transform the difficulties encountered into opportunities in an endeavour to raise an excellent generation that is morally upright and intelligent. This article will discuss the crucial function of Islamic education in fostering responsibility in the face of rapidly advancing technological advancements in both communication and educational resources from the perspective of Hasan al-Banna. This article uses library research techniques to gather a variety of ideas, facts, research findings, and expert opinions along with pertinent analysis. As a result, it is clear how Hasan al-Banna’s viewpoints on Islamic education is in producing a generation that is excellent in every way, including intellectually, materially, morally, and spiritually, where they are collected to the character building.
Abstrak: Kemajuan teknologi diakui telah memudahkan pelajar muda untuk mengakses informasi dan pengetahuan, namun juga membawa perubahan nilai-nilai dalam pandangan hidup masyarakat dan praktik keagamaan mereka akibat kecenderungan menuju kebebasan dan hiper teknologi. Pendidikan Islam harus merespons kondisi ini dengan menerapkan sejumlah langkah taktis untuk mengubah kesulitan yang dihadapi menjadi peluang dalam upaya mendidik generasi yang unggul secara moral dan cerdas. Artikel ini akan membahas peran penting pendidikan Islam dalam membentuk tanggung jawab menghadapi kemajuan teknologi yang pesat dalam komunikasi dan sumber daya pendidikan, ditinjau dari perspektif Hasan al-Banna. Artikel ini menggunakan teknik penelitian pustaka untuk mengumpulkan berbagai ide, fakta, temuan penelitian, dan pandangan ahli beserta analisis yang relevan. Sebagai hasilnya, jelas bagaimana pandangan Hasan al-Banna tentang pendidikan Islam berkontribusi dalam menciptakan generasi yang unggul dalam segala hal, termasuk secara intelektual, materi, moral, dan spiritual yang semuanya tergabung dalam pembangunan karakter.
Modified “SUPERhip2” to Reconstruct Postinfectious Femoral Neck Pseudoarthrosis (Hunka Type 3)
Authors: Jahmani Rami A.
Published: May 2024

Case:

We report a case of a 3-year-old girl who developed a post-infectious femoral neck pseudoarthrosis after a proximal hematogenous femoral osteomyelitis (type 3 according to Hunka classification of the sequelae of the septic hip in children). The patient was treated by a modified “SUPERhip 2” procedure (a reconstructive procedure described to reconstruct congenital femoral neck pseudoarthrosis). This report describes the surgical technique in details and discusses the advantages, pitfalls, and complications and possible complications.

Conclusion:

Our modification simplifies the “SUPERhip 2” procedure. Postinfectious neck pseudoarthrosis was successfully treated, and we believe this modification is applicable for the treatment of congenital femoral neck pseudoarthrosis as well.
Acute Compartment Syndrome in a Football Player With Quadriceps Contusion and Successful Return to Sport
Authors: O'Toole Riley , Hale Martina , Scarcella Michael J.
Published: May 2024

Case:

This report describes the case of quadriceps contusion progressing to acute compartment syndrome (ACS) of the thigh. A 17-year-old football player presented the morning after a direct impact injury to the anterior thigh in intractable pain and pain with short arc motion. He was diagnosed with ACS and underwent successful fasciotomy, ultimately returning to play at 4 months.

Conclusion:

ACS is rare but potential catastrophic progression of quadriceps contusion. Accurate and timely diagnosis followed by appropriate rehabilitation is necessary for optimal outcomes.
Benign Tumors of the Wrist, Hand, and Fingers
Authors: Gocke Thomas V.
Published: May 2024

Most tumors involving the wrist, hand, and fingers consist of skin, soft tissue, and bone. Many of these tumors are benign, with only a small percentage considered malignant. The location of these tumors can contribute to patient apprehension and concern. This article aims to review epidemiology, describe physical characteristics, and review diagnostic imaging studies and treatment options commonly used to treat benign tumors of the wrist, hand, and fingers.
Optimizing Work Efficiency by Addressing Operator Fatigue Concerns
Authors: Agil Mochamad Sofwan , Isma Putra Boy
Published: May 2024

The study conducted at PT. Tjiwi Kimia aimed to assess the fatigue criteria and mental load experienced by production operators of cartoon box in the context of the company's 3-shift operation. Using the Bourdon Wiersma method for fatigue evaluation and the NASA TLX method for mental load analysis, findings revealed varying levels of fatigue and mental burden across different shifts. Notably, the morning shift exhibited "Good enough" speed fatigue but "Doubtful" accuracy fatigue, while the night shift showed "Enough" consistency fatigue. Furthermore, the mental burden was highest during the night shift, categorized as "High." These findings underscore the importance of addressing shift-related fatigue and mental load in industrial settings. Recommendations for implementing 3-shift rotations with weekends off and providing short breaks reflect potential strategies to mitigate worker fatigue and improve overall well-being. Future research could explore additional factors influencing worker fatigue and mental load, such as ergonomic interventions or technological advancements in production processes. Highlight: Shift Work Effects: Assessing fatigue and mental load in industrial settings. Evaluation Methods: Bourdon Wiersma and NASA TLX for worker analysis. Improvement Suggestions: Implementing 3-shift rotations and providing breaks. Keywoard: Fatigue, Mental Load, Production Operators, Shift Work, Industrial Setting
RESONANT VERSES: AN IN-DEPTH ANALYSIS OF THEMATIC CONCERNS IN SANDHYA TIWARIS SELECT POETRY
Authors:   Lecture, Department of English Loyola College, Chennai., Srivastav Manju
Published: May 2024

This article, Resonant Verses: An In-Depth Analysis of Thematic Elements in Sandhya Tiwaris Poetry, presents a comprehensive examination of the rich tapestry of themes woven throughout the poetic works of Dr. Sandhya Tiwari. Renowned for her poignant lyricism and profound exploration of human experiences, Tiwaris poetry encapsulates a diverse range of subjects, including the enduring human spirit, the complexities of grief, and the quest for authenticity amidst a materialistic society.In this critical analysis, we delve into Tiwaris skilful use of language and metaphor, examining how her poems articulate the nuances of emotional states such as melancholy in Melancholy and the deep reverence for mentorship in Farewell to the guiding light. We explore the interplay between the tangible and intangible in her poetry, particularly how she contrasts the allure of material wealth against the more lasting beauty of grace and goodness as depicted in Beautiful Ornaments.The article also investigates Tiwaris engagement with nature and solitude as sources of solace and enlightenment, offering a retreat from the superficiality of the modern world as seen in Withdrawal. Through close readings and thematic analysis, we reveal the consistent threads of introspection, moral reflection, and the celebration of intrinsic values that define her work.
CULTURAL DYNAMICS OF THE KANIKKAR TRIBE: AN ETHNOGRAPHIC INQUIRY
Authors:   Research Scholar School of Social Sciences, M.G. University Kottayam., M. Maya , Babu Abhilash ,   Associate Professor School of Social Sciences, M.G University Kottayam.
Published: May 2024

This ethnographic study delved into the intricate cultural dynamics of the Kanikkar tribe, a marginalized indigenous community residing in the southern regions of Kerala. Through immersive fieldwork and qualitative analysis, the research explored the multifaceted aspects of Kanikkar culture, including their social organization, livelihood, traditional practices, belief systems, cultural identity, and interactions with the surrounding environment. The Kanikkar tribe displayed unique cultures, lifestyles, customs, traditions, religious practices, and rituals. Their lifestyles connected them to the land, forests, rivers, and natural resources. Subsistence practices such as hunting, fishing, agriculture, and gathering sustained them. Traditional clothing, music, dance, and storytelling formed integral parts of their cultural expression. They were renowned for their traditional medicinal expertise, possessing intricate knowledge of herbs and their healing properties. The findings of this inquiry shed light on the resilience of Kanikkar traditions in the face of modernization, as well as the ongoing processes of cultural adaptation and transformation within the community.
REVIEW ARTICLE ON THE EFFECTS OF AYURVEDIC VARNYA HERBS
Authors:   P.G Scholar, Department of Kriya Sharir, Institute for Ayurved Studies and Research, Kurukshetra, Haryana-136118., Sharma Meha , a Deepa ,   P.G Scholar, Department of Kriya Sharir, Institute for Ayurved Studies and Research, Kurukshetra, Haryana-136118., Khatri Manisha ,   Associate Professor, Department of Kriya Sharir, Institute for Ayurved Studies and Research, Kurukshetra, Haryana-136118., Mangal P. C. ,   Professor& HOD, Department of Kriya Sharir, Institute for Ayurved Studies and Research, Kurukshetra, Haryana-136118.
Published: May 2024

In the contemporary landscape, the desire for a luminous complexion has grown remarkably, steering individuals towards an inclination for fair skin. This quest for radiance is witnessing a distinctive shift towards an increased preference for natural products over their synthetic alternatives. The unfolding narrative in the realm of skin enhancement delves into a burgeoning realm, constantly enriched by updated insights and discoveries. Intricately woven into this narrative is the timeless wisdom of Ayurveda, where terms like varÃ¡Â¹Â‡ya, raktaprasadana, and tvacya illuminate the path to skin luminosity. Ayurveda not only encapsulates a historical perspective on skin care but also aligns seamlessly with modern methodologies. Tyrosinase inhibition, a contemporary approach to skin lightening (whitening), finds resonance in Ayurvedic principles, forming a bridge between tradition and innovation. As societal beauty standards evolve, this nuanced interplay between tradition and modernity underscores a unique trajectory in the pursuit of radiant skin. The convergence of ancient wisdom and cutting-edge research epitomizes a distinctive approach to skincare, where the desire for light skin is not merely a trend but a harmonious blend of heritage and progress.
YOGASANAS AND THEIR IMPORTANCE IN STREE ROG
Authors:   Assistant Professor, Department of Prasuti Tantra and Stree Rog, Himalayiya Ayurvedic College and Hospital, Dehradun., Jugran Sonali
Published: May 2024

Yogasanashave today become a mode of treatment. It has gained widespread popularity due to its multifaceted benefits. Practicing yogasanas provide prevention from certain disorders. Non communicable diseases are rising rapidly due to the changing environmental conditions which can be prevented by certain yogasanas,Certain gynaecological disorders including infertility can also be prevented and cured by these asanas. This article focuses on the origin and evolution of yoga practices and also explains some yogasanas beneficial in gynaecological disorders.
PERIOPERATIVE MANAGEMENT OF AN ABDOMINAL EMERGENCY IN A PREGNANT PATIENT OUTSIDE THE OBSTETRICAL SETTING
Authors: Chajai Salim , Zarouali Hamza , Aberouch Larbi , Tadili Jaouad , Kettani Ali , Faroudy Mamoun
Published: May 2024

Acute appendicitis can complicate 1 in 500 to 2000 pregnancies, and can adversely affect maternal and fetal outcomes when the diagnosis and management are delayed. We report the case of a 31 years old prime gravid patient with a gestational age presenting with an acute abdomen evoluating for five days in a non obstetrical hospital. The diagnosis of acute perforated appendicitis with acute intestinal occlusion was made. The patient was treated surgically with hemodynamic, respiratory and metabolic optimization. Fetal well-being was monitored intermittently using point of care fetal ultrasound, by measuring fetal heart rate (FHR) with M-mode on the fetal heart. The patient was transferred shortly after stabilization to a maternal care facility. This case reports highlights diagnostic challenges associated with acute appendicitis in pregnancy, perioperative management and monitoring options outside the obstetrical setting, and the importance of an early transfer to a maternal critical care department.
Local therapy in the postoperative management of patients with lower limb varicose vein disease
Authors: Mokhamad I. N.
Published: May 2024

Introduction. Varicose veins of the lower extremities are one of the most common diseases, affecting 20 to 40% of the population. One of the most common treatment methods is endovenous laser coagulation (EVLC).

Aim. To evaluate the effectiveness of local gel therapy based on escin, heparin and essential phospholipids in the postoperative administration of patients after endovenous laser coagulation.

Materials and methods. A complex treatment of 53 patients with varicose veins of the lower extremities of classes C2-C3 according to the CEAP nomenclature was carried out. Patients were divided into 2 statically homogeneous groups with an equal number. All patients underwent endovenous laser obliteration of the trunk of the great saphenous vein in combination with miniphlebectomy of tributaries on the thigh and lower leg.

Results. In both groups, the largest number were patients with incompetence of the GSV trunk up to the border in /3 and c/3 of the lower leg, with further discharge along the tributaries of the GSV along the medial surface of the lower leg. The failure of the GSV trunk to the level of the knee joint gap was accompanied by the presence of varicose-transformed tributaries along the anterior surface of the thigh, in the area of the knee joint. The addition of Detragel led to the relief of phlebitis and hematomas, a pronounced decrease in pain and edematous syndrome.

Discussion. Transdermal drug delivery has great promise as an alternative to oral and intravenous treatment, especially for patients suffering from chronic diseases. The three-component composition allows you to influence all parts of the pathogenesis of the disease.

Conclusion. The data obtained on the use of local gel therapy based on escin, heparin and essential phospholipids after EVLO of the GSV indicate the need for local therapy to improve the quality of life of patients, their rapid rehabilitation and improve immediate and long-term results.
Methods of preventing surgical site infections
Authors: Morozov A. M. , Sergeev A. N. , Chervinets V. M. , Chervinets J. V. , Guskova O. N. , Skaryakina O. N. , Egorova E. N.
Published: May 2024

Healthcare-associated infections are the most common and relevant to all healthcare facilities of all types. Surgical site infections are the most frequently reported type of healthcare-associated infections. Surgical site infections are also one of the main causes of prolonged hospital stays, prolonged antibiotic therapy, unplanned re-hospitalizations, worsened long-term patient outcomes and the prescription of additional surgical interventions. At present, it is prevention that has been identified as the single most important strategy to combat surgical site infection. The proposed three-stage model combines perioperative interventions as well as interdisciplinary collaboration to continuously improve the quality of care. This approach includes preoperative, intraoperative, and postoperative prevention methods. Current preoperative strategies for the prevention of surgical site infections can significantly reduce the risk of developing this nosology; one important aspect of preoperative prophylaxis includes the identification, elimination, and/or correction of modifiable as well as non-modifiable risk factors. In addition, it is possible to identify intraoperative risk factors, of which the duration of surgical intervention is fundamentally important. Postoperative risk factors include hyperglycemia and diabetes mellitus, postoperative wound care and blood transfusion. Many effective ways of preventing surgical site infections have been developed, which include separate methods of preoperative, intraoperative and postoperative prophylaxis, however, only through the implementation of a comprehensive model that combines all perioperative measures, health care institutions will be able to effectively reduce the incidence of healthcare-associated infections and improve patient outcomes. Despite the fact that currently there is an active development of new methods of surgical site infections prophylaxis, the direct implementation of these technologies in the practical activity of specialists is of primary importance.
principio de división de poderes. Una revisión crítica
Authors: Flores Andrade Anselmo
Published: May 2024

El artículo hace una revisión de las distintas interpretaciones del significado del principio de división de poderes, destacando su poder legitimador para la arquitectura de los Estados modernos. Por otra parte, expone el principio de división de poderes como un marco normativo para el desarrollo de las democracias contemporáneas. Asimismo, confronta el principio de división de poderes con el crecimiento y complejidad de las funciones que realiza el Estado contemporáneo, en particular con la incorporación de órganos autónomos en la vida constitucional. Con lo anterior, se pretende mostrar que el debate sobre la actualidad del principio de división de poderes no ha concluido; por el contrario, debido a los cambios políticos, económicos y sociales de los últimos años aún es pertinente.
Robotic Guardians: Navigating Hospital Isolation Zones for Disease Control
Authors: Keskar Aarya
Published: May 2024

Abstract: In healthcare contexts where human access is limited, particularly in isolation and quarantine rooms, autonomous solutions become critical. This study presents a novel solution to addressing this problem: a line-following robot built for use in hospital isolation units. The robot's operating principle is led by a color recognition system, which responds dynamically to certain colors linked with directing cues. The system's ability to capture vital information by utilizing the ESP32 camera module increases its utility beyond navigation, extending to the collection of patient vitals displayed beside beds. By combining precise navigation with information gathering capabilities, this line-following robot offers a potential solution for tasks in restricted access healthcare environments.
Language Translator Using Deep Learning
Authors: Reddy C. Karthik
Published: May 2024

Abstract: Digital translation (MT) is a process of translating text from one language to another using software by including both computer and language information. Initially, the MT system acquires text translation into the source language by simply associating the meaning of the words in the source language with the target language with the help of grammar. However, such methods did not produce good results due to their failure to capture the various sentence structures in the language. This process of translation is time-consuming and requires skilled craftsmen in both languages. Subsequently, integrated translation methods such as mathematical translation (SMT) and neural translation (NMT) technology have been introduced to address the challenges of legal-based approaches. MT has already shown promising results in bilingual translation. In contrast to SMT, which requires sub-components trained separately in translation, NMT uses one large neural network for training. This paper outlines how to train a repetitive neural network for rearrangement for a source to identify. The default encoder helps to reconstruct the vectors of the target language. Therefore, powerful hardware (GPU) support is required. The GPU improves system performance by reducing training time.
Remote Controlled Agricultural Robot
Authors: Mishra Shreyansh
Published: May 2024

Abstract: The Agri Bot project presents a pioneering endeavor in the realm of autonomous agriculture by seamlessly integrating robotics, IoT, and mobile application development. Utilizing an Arduino UNO microcontroller, ESP32 camera module, servo motors, and various sensors, the system excels in executing precise agricultural tasks such as digging, filling, seed sowing, and fertilizer dispensing. The accompanying mobile application, developed through MIT App Inventor and utilizing Bluetooth communication, provides an intuitive interface for users to remotely oversee and manage the Agri Bot's operations. Beyond its successful hardware and software integration, the project holds transformative potential for traditional farming practices, evident in the incorporation of advanced technologies such as obstacle detection sensors and machine learning for crop recognition. The modular design and collaborative potential of swarm robotics hint at scalability and adaptability for evolving agricultural needs. As the project lays the groundwork for autonomous agriculture, future prospects include autonomous navigation, sustainable power solutions, data analytics for decision support, and enhanced remote monitoring. Collaboration with agricultural experts and ongoing refinements based on real-world feedback are crucial for optimal deployment in diverse farming environments. The Agri Bot project represents a significant milestone in the convergence of technology and agriculture, heralding a future where autonomous systems play a central role in shaping the agricultural landscape.
AI-Powered Autonomous Checkout System for Retail Stores
Authors: Mascarenhas Kishen Vivel
Published: May 2024

Abstract: Auto Bill offers a smart, automated checkout service for shops, leveraging state-of-the-art machine learning and computer vision technologies to provide an exceptional shopping experience. Designed to minimize interactions for security purposes during the pandemic, the innovation lies in utilizing modern techniques like image processing and weight sensors to create a novel shopping experience. This system aims to surpass traditional weight scales by incorporating advanced image recognition technologies, benefiting customers with a highly user-friendly interface, reduced checkout times, and improved accessibility. With a multifaceted approach involving deep learning neural networks and a web-based interface for transactions and inventory monitoring, Auto Bill envisions a future where retail checkout is taken to new heights. Supermarkets adopting this system can enhance customer service throughits advanced machine learning and camera technology, offering a seamless shopping experience. By integrating easily with existing POS systems, this solution streamlines operations and improves overall efficiency in the retail industry. With continuous testing and adjustments, Auto Bill aims to refine retail checkout to unprecedented levels of accuracy and customer satisfaction.
Analisis Penerapan Konsep Mitigasi Tsunami pada Hardscape Taman Kota (Studi Kasus: Taman Krueng Neng)
Authors: Frida Harya , Meutia  , Nopera Rauzi Era
Published: May 2024

Krueng Neng Park is one of the city parks in Banda Aceh which is located on the banks of the Kampong Lamjame river, Jaya Baru District, Banda Aceh. This park with an area of 1.52 ha is one part of the Green Open Space (RTH) development. its location on the banks of the Surin River is the main attraction of this park. Krueng Neng Park is one of the parks that was affected by the tsunami wave in 2004. Due to its location in an area designated as a tsunami mitigation-based area, Krueng Neng Park needs to apply the concept of tsunami mitigation. The existence of the Krueng Neng park raises questions for researchers, especially regarding the hardscape application of the tsunami mitigation concept that exists in the Krueng Neng park, based on the applicable standardization principles. With the aim of analyzing the application of the existing tsunami mitigation concept to the Krueng Neng park, and recommending an appropriate tsunami mitigation concept to the Krueng Neng park.
Identifikasi Konsep Privasi pada Indekos Massa Banyak, Studi Kasus Indekos Mahasiswi di Banda Aceh
Authors: Annisa Rafika , Bakri Maysarah , Fitri Rizky Sarvina
Published: May 2024

Abstract. The indekost are businesses that rent out rooms in a house for a certain period and with a set payment schedule. Boarding houses involve owners and tenants who have no family ties and occupy the same building or site. To support its role as a place to live, the need for privacy in boarding houses is very important. This is based on the assumption that, compared to other building functions, a dwelling has the highest level of privacy requirements. This study was conducted to take a closer look at the efforts of boarding houses to maintain privacy architecturally. The object of research is in the Darussalam and Batoh Regions which are educational areas that have many boarding houses around them. This study uses a qualitative descriptive methodology. Data were collected through observation. The result of the research shows that research objects with separate masses have good privacy qualities. Another important finding is the orientation of the building and the placement of openings affect the quality of privacy in buildings.
Persepsi Masyarakat Terhadap Penggunaan Pedestrian Sebagai Ruang Publik (Studi Kasus : Area Pedestrian Jalan Pelabuhan Ulee Lheue)
Authors: Yuli Elfizar Nanda , Dyena Meutia Zya , Aulia Fahmi , Araby Zardan
Published: May 2024

Abstract. Public open space is a place that can fulfill a need that is functional. Public open space in the Ulee Lheue considered still lacks that this area requires special attention to well ordered. Researchers conducted research in the Ulee Lheue because this region is particularly at the area of pedestrian roads Ulee Lheue port there are still many obstacles. An area used as a pedestrian has been used for a trade for small street vendors located in that area. Researchers collected perception of the community for getting data on pedestrian Ulee Lheue in the area. This study in a qualitative approach case study and use the data collection techniques in a searching manner a literature review, observation, interview and documentation. This study also uses the data analysis descriptive heading for described the data obtained through research. The result showed that the pedestrian Ulee Lheue were succesful with proper facilities mand infrastructure. Ulee Lheue public space in an area used quite well. Many visitors do activities in the area of pedestrian street vendors. The use of the pedestrian by street vendors can interfere with the activity of the community especially the riding a motorcycle, so in the region every day deadlocked result of traders who use the pedestrian and the roads as a trading.
Multiple effects of L-leucine in Escherichia coli lead to L-leucine sensitive growth in the absence of dephospho-PtsN.
Authors: Kumar Neeraj , Sardesai Abhijit
Published: May 2024

In E. coli K-12, absence of dephospho-PtsN, is thought to cause
an L-leucine sensitive growth phenotype (Leu ) by
hyperactivated K uptake mediated impairment of the
expression of the ilvBN operon, encoding subunits of the L-valine
(Val) sensitive acetohyrodxyacid synthase I (AHAS I), that renders
residual AHAS activity susceptible to inhibition by Leu and K
. This is thought to lead to AHAS insufficiency and a
requirement for isoleucine (Ile). Herein we provide an alternate
mechanism for Leu of the ∆ ptsN mutant.
Genetic and physiological studies with suppressors of the Leu
, indicate that impaired expression of the
ilvBN operon jointly caused by the absence of dephospho-PtsN and
the presence of Leu coupled to Leu mediated repression of expression of
AHAS III leads to AHAS insufficiency rendering residual AHAS activity
susceptible to chronic Val stress that may be generated by exogenous
Leu. Hyperactivated K uptake and an elevated
α-ketobutyrate level, mediate elevation of ilvBN expression, and
alleviate the Leu . The requirement of dephospho-PtsN
as a positive regulator of ilvBN expression, may buffer Ile
biosynthesis against Leu mediated AHAS insufficiency and protect AHAS I
function from chronic endogenous Val generated by Leu and could be
realised in certain environments that impair AHAS function.
Proving equivalence of originator and an authorized generic drug following EMA draft guideline on quality and equivalence of topical products
Authors: Eichner Adina , Mrestani Yahya , Hukauf Martin , Wohlrab Johannes
Published: May 2024

Aim: Today, the approval for a generic topical product includes the
presentation of therapeutic equivalence to the originator based on
clinical trials. To facilitate this procedure, in 2018 the European
Medicines Agency (EMA) published a draft guideline on quality and
equivalence of topical products, which includes request parameters
regarding the quality of the newly developed generic product and test
protocols for the implementation of equivalence tests with respect to
efficacy. Methods: To date, no data are available on the quality and
evidence of the proposed test conditions. In this study, we performed an
in vitro penetration test (IVPT) following the terms of the EMA draft
guideline on two authorized topical products for which therapeutic
equivalence was already proven during the approval process. Results: The
complex biometric data processing revealed that in vitro equivalence
could not be observed for all skin sections for both, originator and
generic product. Moreover, the necessity of the negative control
proposed in the draft guideline is more as questionable. From the
results presented, there were indications that a reduced number of skin
donors would be sufficient in order to achieve statistically significant
equivalence in the comparison of all applied formulations. Here n=7
donors was proposed instead of n≥12 as the EMA draft guideline demands,
decreasing simultaneously the degree of biodiversity. Moreover, a higher
number of independent replicates (n>2) is proposed for
proper statistics. Conclusion: This bioequivalence study shows
insufficient parameters in the EMA draft guideline, which should be
discussed.
Photoredox-Catalyzed Metal-free Regio- & Stereoselective C(sp2)-H Amination of Enamides with N-aminopyridium salts
Authors: Qin Zheng-Bao , Ni Kun , Wang Li , Wu Xiao-Di , Zhang Yu , Zhao Kai
Published: May 2024

A visible-light-induced photoredox-catalyzed regioselective and
stereoselective C(sp)-H amination of enamides with
bench-stable and easily accessible N-aminopyridium salts is
developed, affording synthetically and biologically prominent vicinal
1,2-diamine scaffolds in broad substrate scope and excellent functional
group compatibility. The transformation proceeded through a radical
pathway involving the Giese addition of the relatively electrophilic
N-centered amidyl radical species to nucleophilic β-olefinic
position of enamides followed by the ensuing single electron oxidation
and β-H elimination, delivering geometrically-defined
Z-configured β-amino enamides. The operational simplicity,
environmentally friendliness and cost efficiency of this methodology has
paved a new avenue to enrich the arsenal of synthetically crucial
functionalized enamides and their derivatives.
Unidirectional gene flow from the Gulf of Mexico to the Atlantic Ocean in bonnethead sharks (Sphyrna tiburo)
Authors: Black Kristina , Liu Kathy , Graham Jasmin , Wiley Tonya , Gardiner Jayne , MacDonald Catherine , Matz Mikhail
Published: May 2024

Gene flow is important for maintaining the genetic diversity required
for adaptation to environmental disturbances, though gene flow may be
limited by site fidelity in small coastal sharks. Bonnethead sharks
(Sphyrna tiburo) - a small coastal hammerhead species - demonstrate site
fidelity, as females are philopatric while males migrate to mediate gene
flow. Consequently, bonnetheads demonstrate population divergence with
distance and Atlantic populations are genetically distinct from those of
the Gulf of Mexico. Indeed, Florida forms a vicariant zone between these
two bodies of water for many marine species, including some sharks.
However, while bonnetheads are expected to have limited dispersal, the
extent and rate of bonnethead migration remains uncertain. Thus, we
aimed to determine their dispersal capacity by evaluating connectivity
between disparate populations from the Gulf of Mexico and Atlantic
Ocean. Using 10,733 SNPs derived from 2bRAD sequences, we evaluated
genetic connectivity between Tampa Bay on the Gulf Coast of Florida and
Biscayne Bay on the Atlantic coast of Florida. While standard analyses
of genetic structure revealed little differentiation between Tampa Bay
and Biscayne Bay populations, demographic history inference based on the
site frequency spectrum favored the model with divergence between 2000 -
6000 years ago, with continuous unidirectional gene flow from Tampa Bay
to Biscayne Bay. Combined with prior findings of small-scale genetic
divergence in bonnethead mitochondrial (female-transmitted) loci, our
findings support the hypothesis that female bonnetheads are highly
philopatric while male bonnetheads often migrate over relatively large
distances (>300 miles) to find mates. Together, these
results provide optimism that under proper management, a small-bodied
globally Endangered shark can undergo long migrations to sustain genetic
diversity.