bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamical Response of Solar Wind Charge Exchange Soft X-Ray Emission in Earth’s Magnetosphere to the Solar Wind Proton Flux
Authors: Zhang Yingjie , Sun Tianran , Carter Jennifer A. , Sembay Steve , Koutroumpa Dimitra , Ji Li , Liu Wenhao , Wang Chi
Published: May 2023

This work studies the dynamic response of solar wind charge exchange (SWCX) soft X-ray emission in the Earth’s magnetosphere to the solar wind proton flux. Unlike previous studies that attempted to use complex magnetohydrodynamic models to match the details of observed SWCX of a necessarily limited number of cases, this work focuses on determining the changes over individual observations in a much larger sample. To provide the cleanest test, we selected XMM-Newton observations when the solar wind proton flux changed suddenly by a factor greater than 1.5 and calculated the correlation coefficient between the SWCX emission in the 0.5–0.7 keV band and the proton flux. We find that the dynamical response is weak when the solar wind proton flux is low (<10,000 n*km/cc/s) because its variation is smaller than the uncertainty due to other emission components, but this response increases with the proton flux and its change value. The response is improved when the valence state of solar wind ions is high, as a higher abundance of ions generating SWCX can produce a greater correlation even though the proton flux is relatively low. It is conducive to the study of interplanetary coronal mass ejections (ICMEs) because ions in ICMEs are usually highly ionized. For XMM-Newton, the 0.5–0.7 keV band shows the strongest correlation, as the instrumental response decreases at lower energies and the SWCX emission decreases at higher energies. Moreover, the closer the satellite line of sight is to the subsolar magnetopause with the strongest SWCX emissivity, the better the correlation.
Oscillation theorems for fourth-order quasi-linear delay differential equations
Authors: Masood Fahd , Moaaz Osama , Santra Shyam Sundar , Fernandez-Gamiz U. , El-Metwally Hamdy A.
Published: May 2023

In this paper, we deal with the asymptotic and oscillatory behavior of quasi-linear delay differential equations of fourth order. We first find new properties for a class of positive solutions of the studied equation, $ \mathcal{N}_{a} $. As an extension of the approach taken in [1], we establish a new criterion that guarantees that $ \mathcal{N}_{a} = \emptyset $. Then, we create a new oscillation criterion.
Min-max method for some classes of Kirchhoff problems involving the $ \psi $-Hilfer fractional derivative
Authors: Azumi Hadeel Zaki Mohammed , Shammakh Wafa Mohammed Ahmed , Ghanmi Abdeljabbar
Published: May 2023

In this work, we develop some variational settings related to some singular $ p $-Kirchhoff problems involving the $ \psi $-Hilfer fractional derivative. More precisely, we combine the variational method with the min-max method in order to prove the existence of nontrivial solutions for the given problem. Our main result generalizes previous ones in the literature.
Association of personal and equipment-related factors on ACL injury risk in alpine skiers with cautious or risk-taking behaviour: A case-control study
Authors: Ruedl Gerhard , Posch Markus , Pocecco Elena , Tecklenburg Katja , Schliernzauer Birgit , Kennedy Michael D. , Faulhaber Martin , Burtscher Martin
Published: May 2023

Background

In recreational alpine skiing ACL injury risk depends on the interaction of individual characteristics and behaviours as well as on equipment-related factors.

Aim

to evaluate if and to what extent personal characteristics and equipment-related parameters are associated with ACL injury risk in cautious and risk-taking recreational alpine skiers.

Methods

A retrospective questionnaire-based, case-control study of ACL-injured and uninjured in a cohort of cautious as well as risk-taking recreational skiers was conducted. Participants self-reported their demographics, skiing skill level, and risk-taking behaviour. Ski length, side-cut radius, widths of the tip, waist, and tail were recorded from each participant's skis. Standing heights at the front and rear components of the ski binding were measured with a digital sliding caliper, and a standing height ratio between the front and rear components was calculated. Ski boot sole abrasion at the toe and heel pieces was also measured with the digital sliding caliper.

Results

In total, 1068 recreational skiers (50.8% females) with a mean age of 37.8 ± 12.3 years participated, of whom 193 (22.0%) sustained an ACL injury, and 330 (30.9%) participants reported a risk-taking behaviour. Results of the multiple logistic regression analyses revealed that a higher age, a lower skill level, a higher standing height ratio, and greater ski boot sole abrasion at the toe as well as heel pieces were independently associated with an increased ACL injury risk in both the cautious and the risk-taking group. Among cautious skiers, a longer ski length was an additional significant risk factor for sustaining an ACL injury. In conclusion, the same personal and equipment related characteristics contribute to an increase in the ACL injury risk regardless of risk-taking behaviour, with the only difference that longer skis represent an additional risk factor in cautious skiers.
Transmedia Adaptation, Sonic Affect, and Multisensory Participation in Contemporary Chinese Danmei Radio Drama
Authors: Hao Yucong
Published: May 2023

Danmei, a genre also known as boys’ love, first developed in China in the 1990s under the influence of Japanese subculture in the 1990s, but it has diverged from its Japanese antecedents in the last decade. Recent Chinese cultural products of danmei, no longer confined to a subcultural group, have attracted mainstream attention and been widely adapted into a variety of popular media forms. In this paper, with the case study of radio drama Grandmaster of Demonic Cultivation (2016), I examine how queerness is explored and experienced through the affective expressivity inherent in voice as well as the interactive interface of danmaku, with which listeners can experience and articulate queer fantasy in a relatively unobstructed way. As the genre of danmei has been subject to persistent state censorship, this paper further explores strategies of containment and tactics of negotiation deployed by both content producers and cultural consumers.
Augmenting Learner Support Services With the Use of Blockchain Technology
Authors: Pulist S. K.
Published: May 2023

The potential of implementation of blockchain technology in education to manage different internal processes seems quite obvious. The chapter discusses different areas of the open and distance learning system in general and learner support services in particular in which use of BCT can be a promising pay-off. The chapter focuses on the introduction of blockchain: how it started and recent developments, open and distance learning system in India, learner support services in open and distance learning, BCT in India, strategies of the government of India to augment blockchain, application of blockchain in open and distance learning in general and learner support services in particular, challenges in implementation of blockchain in open and distance learning and learner support in the country, and its implications.
Potential of Internet of Things (IoT) and Blockchain Technology in the Collaboration and Integration of the Retail Supply Chain
Authors: Zheng Xinyu , Ali Syed Imran
Published: May 2023

The application of Industry 4.0 technologies in the supply chain of organisations has progressively become a hot topic. These disruptive technologies have contributed to enhance efficiency, performance, and sustainability in the organizational ecosystems. However, the globalized retail industry is confronting several challenges pertaining to collaboration and integration. Hence, a thorough review is imminent to explore the potentials of Industry 4.0 technologies such as internet of things (IoT) and blockchain technology to address the challenge of achieving collaboration and integration across the retail supply chains. To address this, a systematic literature review (SLR) methodology is adopted to retrieve current academic publications from the SCOPUS database for the period of 2018-2021. Descriptive and thematic analysis is done to reveal various characteristics, themes, potentials, and relationships in achieving collaboration and integration across the retail supply chains. The findings also suggest some suggestions for small and medium enterprises and future directions.
Relationship Between Cause-Related Marketing and Shared Value in Pandemic Times
Authors: Blanco Lidia Rangel , Vera Madelyn Avila , Walle Ramiro Esqueda
Published: May 2023

Cause-related marketing (CRM) is a corporate strategy that assertively communicates the degree of commitment made due to social or philanthropic action, and in some cases, it actively involves consumers in this practice through the marketing of products or services for a cause. These activities are represented as a “shared value” to the extent that both companies and social causes mutually benefit. This research aims to examine the link between CRM and the construction of shared value, so a theoretical discussion on the subject is conducted regarding the post-pandemic environment due to the significant influx of the use of information and communication technologies (ICT). According to the literature review, cause-related marketing as a strategic tool has the potential to create shared value through effective communication management of corporate philanthropy and corporate social responsibility activities.
The Relationship Between Sustainable Leadership and Organizational Identification in Universities
Authors: Karabetyan Lina
Published: May 2023

Sustainable leadership style has garnered significance as a multidimensional philosophy that shapes the future, prioritizes the organization-environment relationship, acknowledges the organization's impact on the environment, and encompasses economic, cultural, social, and ethical dimensions. Education is recognized for its critical role in fostering the development of a sustainable society and economic system. Notably, sustainable leadership is also crucial in academic settings for the identification and implementation of essential indicators within the governance, strategy, and communication framework of a sustainable university. This study aims to examine the association between sustainable leadership and organizational identification among 614 academicians employed in research universities in Istanbul, using structural equation modeling. The findings of the analysis indicate a statistically significant positive relationship (β=0.389, p<0.01) between sustainable leadership and organizational identification.
The Effects of Fractional Relaxation Time and Magnetic Field on Blood Flow through Arteries along with Nanoparticles
Authors: Abdulhameed Mohammed , Babagana Babakura , Markus Samaila , Yakubu Dauda Gulibur , Adamu Garba Tahiru
Published: May 2023

In this paper, we report the effects of fractional relaxation time on the parameters of blood flow together with magnetic particles through straight circular cylindrical arterial segment. A mathematical model of blood flow subject to pulsatile pressure gradient in the axial direction with external magnetic field applied normal to the direction of flow is presented. Combining the momentum equation together with the Maxwell model parameter appropriately, leads to the governing fractional partial differential equation which permits to obtain the velocity profile of blood along with magnetic particles. By adopting the non-dimensionalized form of the new version of the governing fractional partial differential equation allowed us to obtain the dimensionless relaxation time parameter λ1 which controls blood flow conditions. Solving the fractional partial differential equations using Laplace and finite Hankel transforms we found that the influence of the order of Caputo's fractional time-derivative and fractional relaxation time on the blood flow parameters with magnetic particles are enormous. The graphical results plotted of different influential parameters are presented and discussed in details. The velocities of blood flow and that of magnetic particles are reduced under the influence of the external magnetic field and the relaxation time parameter. The magnetic particles are assumed to be uniformly distributed within the blood, since they are flowing in the same axial direction designated by along a circular cylindrical coordinates of radius. This is a very good indication that blood velocity can be controlled by the application of external magnetic field as well as the relaxation time parameter during treatment to avoid tissues damage. The present study has important applications in magnetic field control of biotechnological processes, bio magnetic device technology, biomedical engineering and pathology. Keywords: Arterial segment, Blood flow, Relaxation time, Magnetic field, Magnetic particles
Application of Strontium-Doped Bismuth Ferrate in Lithium-Sulfur Battery Cathode
Authors: Liu Yang , Yang Cheng Tao
Published: May 2023

The modification of high-performance lithium-sulfur battery cathode have been extensively studied. Suppressing the shuttle effect of polysulfide, solving the volume expansion of sulfur and the poor electrical conductivity of sulfur are the main directions for scientists to modify the cathode. Here we prepared bismuth ferrate powder doped with different molecular percentages of strontium by sol-gel method. Compared with the unmodified cell, the capacity and cycle stability were improved by adding as-prepared material to the cathode, which indicates that bismuth ferrate doped with certain amount of strontium plays a positive role in the cathode material modification.
Exosomes from Cyclic Stretched Periodontal Ligament Cells Induced Periodontal Inflammation through miR-9-5p/SIRT1/NF-κB Signaling Pathway
Authors: Wu Yaqin , Qu Fang , Zhang Yifan , Song Yingshuang , Zhong Qi , Huang Yujie , Wang Yingying , Cao Ximeng , Fan Zhen , Xu Chun
Published: May 2023

Abundant evidence demonstrates that mechanical stress could induce an inflammatory response in periodontal tissue, but the precise mechanism remains unclear. In the past few years, periodontal ligament cells (PDLCs), as the most force-sensitive cells, have been investigated in depth as local immune cells, associated with activation of inflammasomes and secretion of inflammatory cytokines in response to mechanical stimuli. However, this study innovatively inspected the effect of PDLCs on the other immune cells after stretch loading to reveal the detailed mechanism by which mechanical stimuli initiate immunoreaction in periodontium. In the present study, we found that cyclic stretch could stimulate human PDLCs to secret exosomes and that these exosomes could further induce the increase of phagocytic cells in the periodontium in Sprague-Dawley rats and the M1 polarization of the cultured macrophages (including the mouse macrophage cell line RAW264.7 and the bone marrow-derived macrophages from C57BL/6 mice). Furthermore, the exosomal miR-9-5p was detected to be overexpressed after mechanical stimuli in both in vivo and in vitro experiments and could trigger M1 polarization via the SIRT1/NF-κB signaling pathway in the cultured macrophages. In summary, this study revealed that PDLCs could transmit the mechanobiological signals to immune cells by releasing exosomes and simultaneously enhance periodontal inflammation through the miR-9-5p/SIRT1/NF-κB pathway. We hope that our research can improve understanding of force-related periodontal inflammatory diseases and lead to new targets for treatment.
Uveitis in patients with oligoarticular juvenile idiopathic arthritis and juvenile spondyloarthritis/enthesitis related arthritis: is there any difference?
Authors: Martins A. , Ganhão S. , Oliveira Pinheiro F. , Granjo Morais C. , Rodrigues M. , Leuzinger-Dias M. , Figueira L. , Brito I.
Published: May 2023

Juvenile idiopathic arthritis (JIA) is the most common systemic disease causing uveitis in childhood and adolescence.
Skin Behind the Bars!
Authors: Ramteke Komal , Kar Sumit , Patrick Safa , Sawant Ajinkya , Manwar Pooja , Sonkusale Pratiksha , Nandwani Subhor
Published: May 2023

Background:

Prisoners fall in the most vulnerable population group, but the health issue of this group is the most understudied. The various dermatological conditions that hamper their overall health and quality of life needs to be identified and serious measures should be undertaken for preventing them.

Objectives:

This study is one of the rare studies that aim to identify the dermatosis pattern and to relate with its etiological factors and suggest preventive methods to be undertaken for it.

Materials and Methods:

Total three visits were made to the district jail located in Central India over a period of 8 months, and the prison inmates were clinically examined. The data was recorded and results were drawn.

Results:

Scabies accounted for 31.51% while dermatophytes accounted for 30.83%. Other dermatoses seen were acne vulgaris (5.17%), allergic contact dermatitis (ACD) in 5.03%, pyoderma (2.71%), urticaria (2.86%), and tinea versicolor (2.62%). These were followed by the other dermatoses such as milia (1.81%), alopecia areata (0.5%), and irritant contact dermatitis (0.5%); viral infections such as herpes labialis (0.45%) and molluscum contagiosum (0.45%); and pigmentary disorders such as vitiligo (0.65%) and melasma (1.16%). Three new cases of Hansen's disease were diagnosed clinically (1.75%).

Conclusion:

We found that common dermatoses were scabies and fungal infections which are due to the overcrowding and poor hygiene facility in the prison premises. During the subsequent visits, the number of dermatophyte infections declined which may be attributed to patient counseling and awareness regarding hygiene and general cleanliness which was provided by us to the inmates in all previous visits. A detailed look into the matter may improve the overall dermatological health of the inmates.
Apremilast Titration
Authors: De Abhishek , Sarda Aarti , Dhoot Dhiraj , Barkate Hanmant
Published: May 2023

Background:

Apremilast is recommended to titrate in initial period to reduce adverse effects (AE). But inspite of that, in India; many dermatologists experienced a lot of AE resulting in discontinuation of therapy. As a result, many of them have adapted to titrate the dose in different ways.

Objectives:

To evaluate the AE profile and rate of discontinuation of apremilast during initial titration in different ways. Materials and

Methods:

A multicentre, retrospective data analysis was done at 121 dermatology clinics across India in the adult patients diagnosed with chronic plaque psoriasis and prescribed at least one dose of apremilast. Patient characteristics and data were obtained from medical records when available.

Results:

Out of 582 patients, 175 were prescribed apremilast starter pack in licensed dose (Group 1); 202 were prescribed starter pack in OD dosing (Group 2) for 13 days and 205 were prescribed 2 starter packs in OD dosing (Group 3) for 26 days. 45.14% had AE in Group 1 whereas 36.63% and 30.24% had in Group 2 & 3 respectively. Gastrointestinal upset, headache & nausea were most common. In Group 1, 17.71% of patients discontinued apremilast whereas 16.33% and 10.24% discontinued in Group 2 & 3 respectively. On comparison within group, Group 3 had significant difference over Group 1 (p value <0.05).

Conclusion:

It is concluded that slower titration of apremilast in initial phase leads to lesser AE profile and hence discontinuation of therapy and thus increasing adherence.
Giant Cutaneous Epithelioid Angiomatous Nodule
Authors: Dave Jayati Shailesh , Dongre Atul M , Mahajan Sunanda Arun , Khopkar Uday S
Published: May 2023

Cutaneous epithelioid angiomatous nodule (CEAN) is an uncommon benign vascular proliferation that presents as a reddish solitary nodule. Less than 60 cases have been reported in the literature. As it is benign, the prognosis is good, but it is sometimes difficult to differentiate it from other vascular neoplasms. A 16-year-old male presented with a single, large, brownish multinodular swelling over the left pinna. Biopsy showed conglomeration of epithelioid endothelial cells with eosinophilic cytoplasm in the dermis. These cells stained positive for CD31 and CD34. Diagnosis of CEAN was made
“What Lies Beneath” – Macrophage Activation Syndrome Unveiled Systemic Lupus Erythematosus
Authors: Prathibha JP , Pai Vivek , Ishwara Bhat. P
Published: May 2023

Macrophage activation syndrome (MAS) is a potentially fatal condition characterized by massive systemic inflammatory response in the setting of a myriad of systemic disorders such as autoimmune collagen vascular disease, infections, drug-induced, and malignancies. It falls under a group of disorders known as hemophagocytic lymphohistiocytosis of which familial and acquired types have been described. Here, we report a case of acquired MAS secondary to acute systemic lupus erythematosus (SLE). Early diagnosis and timely intervention resulted in a favorable outcome.
Association of the dietary inflammatory index with phenotypic age in the United States adults
Authors: Sun Mengzi , Fang Jiaxin , Gao Wenhui , He Yue , Ma Yanan , Jin Lina
Published: May 2023

OBJECTIVES: One of the underlying mechanisms of aging is chronic inflammation, which has been closely associated with daily diet. Phenotypic age (PhenoAge) has been used as an index to track the aging process before diseases show clinical symptoms. The present study aimed to explore the association between the dietary inflammatory index (DII) and PhenoAge.METHODS: In total, 9,275 adults aged 20 years old and over in the National Health and Nutrition Examination Survey were involved in this study. Dietary patterns were classified as pro-inflammatory or anti-inflammatory according to the DII. PhenoAge was regarded as a continuous variable, and linear regression was used to explore its association with dietary inflammation. Stratified analyses by sex, age, race, physical exercise, smoking status, drinking status, and body mass index were used to test the sensitivity of these associations.RESULTS: The median value of PhenoAge was 38.60 years and 39.76 years for the participants with anti-inflammatory and pro-inflammatory diets, respectively. A pro-inflammatory diet was positively associated with PhenoAge (β=0.73; 95% confidence interval, 0.31 to 1.14), compared with participants who had an anti-inflammatory diet. There was an interaction between dietary inflammation and age for PhenoAge (pinteraction<0.001). The strength of the association between a pro-inflammatory diet and PhenoAge was stronger as age increased.CONCLUSIONS: A pro-inflammatory diet was associated with a higher PhenoAge, and the association was strongest in the elderly. We recommended reducing dietary inflammation to delay phenotypic aging, especially for the elderly.
Identidades y exposición a las violencias online.
Authors: Romo Parra Carmen , Sell Trujillo Lucía , Vera Balanza Teresa , Delgado Peña José Jesús
Published: May 2023

Introducción: A través de las redes sociales circulan ideas que promueven la justicia y la igualdad, permitiendo, a su vez, la propagación de mensajes de odio que favorecen el ejercicio de la violencia online. Bajo estas premisas, a partir de la percepción de la población juvenil dentro del territorio de la Comunidad Autónoma de Andalucía, se cuantifica, describe y sistematiza, desde una perspectiva de género, las violencias que transitan en las redes sociales. Metodología: desde un enfoque cuantitativo, se realiza una encuesta a través de cuestionario. El formulario se distribuye entre la población comprendida entre los 14 y los 30 años de edad, utilizando la técnica de bola de nieve, consiguiendo registrar un total de 938 participaciones. Resultados: se muestra un impacto diferenciado de las violencias en función del sexo y de la orientación sexual, en tanto que son más las mujeres y sobre todo las personas que se declaran como no binarias las que más agresiones han recibido, así como aquellos sujetos definidos con una orientación sexual no heteronormativa. Respecto a las temáticas y las categorías sistematizadas a partir de los relatos violentos recabados, claramente las referidas al aspecto físico y a las posturas políticas e ideológicas concentran casi la mitad de los comentarios totales. Discusión y conclusiones: se profundiza en el análisis de las violencias en red, especialmente volcadas en el ataque a los cuerpos no normativos, las identidades subversivas y las subjetividades diversas.
Engineering Process of Nonlinear Vibration Isolator on Application of an Electrical Drive for Commercial Vehicle
Authors: Schroth Ruediger , Wirz Alexander
Published: May 2023

Engineering of solutions for vibration challenges consists of several steps. Each of them needs different methods, for most steps, several approaches are valid. This work describes one efficient way to get from customer wishes over calculation methods and experimental results as far as the lifetime calculation. The example is an all-metal cushion used as a spring-damper system, that solves vibration problems of the suspension of an electrical drive for a commercial vehicle used in a city.

Metal cushions for vibration isolation are used where high dynamic stresses occur or the environmental conditions overwhelm rubber solutions. So, they are a perfect solution for vibration isolation in industrial environments as well as in railway, automotive and aerospace sectors. Additionally, the progressive stress-deflection behavior and the high damping offer advantages for a wide range of applications.

A Design of Experiment was necessary to define the parameters for an analytical equation to describe the nonlinear force-deflection characteristics of metal cushions. After calculating a valid metal mesh that satisfies the customer requirements, quasi-static measurement on prototypes is performed. Again, the nonlinearity is in focus as working point during the vibration stress. Confirming the calculated results, the lifetime of the cushions needs to be examined. Here, the comparison of the load, out of the calculated and measured results with the load from cushion specific S-N curves lead to reliable results.

The work will show the whole development process on the example of an electrical drive in a commercial vehicle that is running in a city loop.
Probabilistic Metamodels to Quantify Uncertainties in Electric Powertrain Whining Noise Contribution
Authors: Prakash Vinay , Sauvage Olivier , Gagliardini Laurent , Antoni Jérôme
Published: May 2023

With electromobility, vehicles are becoming quieter due to the presence of electric motors that replace internal combustion engines. The interior cabin noise of electric vehicles is characterized by high-frequency components that can be annoying and unpleasant. Therefore, it is essential to analyse the NVH behaviour of e-powertrains early in the design-phase. However, this induces inherent uncertainties during the design process related to the operating conditions, geometrical parameters, measurement techniques, etc. that need to be quantified with fast and comprehensive stochastic models.

In this work, we first present a deterministic framework to provide first-order estimations of the e-powertrain’s interior whining noises, combining both the airborne & structure-borne contribution with data-driven NVH transfers meta-models. Subsequently, stochasticity is induced in the deterministic models considering random sampling of operating conditions and the chosen geometrical parameters for the e-machine under assessment. At each stage, metamodels (or surrogates), developed in the Bayesian framework, take into account the uncertainties which are propagated from operating conditions to whining noise contribution inside the cabin. The work is demonstrated on an interior permanent magnet synchronous motor which is widely used in electric vehicles traction drives.
On Papulifères, putative ciliate cysts of diverse morphologies, with new observations from the plankton of the Chukchi Sea (Arctic Ocean)
Authors: Dolan John R. , Yang Eun Jin , Moon Jong-Kuk
Published: May 2023

In the early 20th century, Alphonse Meunier described "Papulifères" as a group of enigmatic forms of unknown taxonomic affinity characterized by possessing a hyaline pimple, a "papula". In the early 1980's Papulifères were equated with cysts of tintinnid ciliates. The most conspicuous forms, the large Fusopsis, have been widely found, and are now known to resemble the cyst of a certain species of oligotrich ciliate (i.e., Cyrtostrombidium boreale). Thus today, Papulifère forms are often assumed to be cysts of oligotrich ciliates. Here we report on 26 Papulifère forms, of more or less distinct morphologies, found in the plankton of the Chukchi Sea. We found forms resembling some of those described by Meunier, and recorded here for the first time since Meunier's reports, and others that do not resemble any of Meunier's Papulifères. Here, we first review the literature on Papulifères, then we present the surprising variety of forms we found in Chukchi Sea, and for some, we provide for the first time data on morphological variability. With this report we have expanded the catalogue of observed Papulifère forms and documented variability in the dimensions of some morphotypes. However, we urge caution in assigning a ciliate species name to any given Papulifère form in the absence of corroborating data. There is a need for observational and/or sequence-based data to elucidate the identity of Papulifère forms.
A Study on the Operation of College Liberal Arts Education for the Improvement of Quantitative Reasoning Competency as Data Literacy
Authors: Shim Sangdeok , Kim Hyeonjeong
Published: May 2023

The goal of this study is to suggest the potential and significance of quantitative reasoning education as a college liberal arts program and to come up with methods to improve it. To do so, this study analyzed the case of  at S National University, presenting its achievements, weaknesses, and improvement plans. From the first semester in 2020,  at S National University has been offered as a semi-compulsory subject with the purpose of cultivating quantitative reasoning based on quantitative relationships and computational thinking for everyday algorithms. In the class, instructors refrain from using mere problem solving using mathematical and/or scientific formulas, and instead an activity-oriented learning approach is emphasized. This allows for the students to interpret quantitative data based on logical algorithms. According to a survey about this subject, most students were satisfied with its contents and reported that it had helped them solve problems creatively based on quantitative and computational thinking. Nevertheless, various problematic issues such as the low enrollment of students in the humanities and social sciences, the dualization of subject operation between classes, and the difficulty in securing lecturers, were raised. To address these issues, it is necessary for us to expand awareness among students that  aims to promote thinking ability through the understanding and interpretation of quantitative data. Also, it is important that we have faculties that operate on a consistent basis, so that the courses offered are able to meet the goals of the subject. By applying these improvements, the effort to develop liberal arts subjects that enhance students’ data-driven scientific thinking should be continued.
Research Trends in Liberal Arts Studies Before and After the COVID-19 Pandemic Using LDA Topic Modeling
Authors: Yoo Jungmin , Lee Kyeongja
Published: May 2023

This study analyzes the changing trends of research topics in liberal arts studies before and after the COVID-19 pandemic. It aims to investigate the impact of the pandemic on research trends in liberal arts studies, identify changes and new trends in recent years with the pandemic, and contribute to the search for the future direction of liberal arts studies in the post-COVID-19 era. To achieve these objectives, we applied keyword frequency analysis and LDA topic modeling analysis as text mining technologies to analyze the keywords and topics of research papers in liberal arts education before and after the pandemic. Our findings revealed meaningful differences in the topics and keywords of papers in liberal arts education studies before and after the COVID-19 pandemic. We interpret these results as reflecting the changes and directions of liberal arts education in the actual field. We also analyzed individual papers on extracted topics and keywords to more elaborately interpret the results and the meaning of the analyses. The results showed that new topics, such as COVID-19 and untact, emerged after the pandemic. The frequency of topics related to online education also increased after the pandemic. We also found an expansion of convergence and integration related to research topics in liberal arts education, as well as a considerable increase of interest in topics regarding artificial intelligence, literacy, and PBL after the pandemic. Based on the interests of researchers and trends in liberal arts education research, this study contributes to ongoing efforts to learn more about the impact of COVID-19 on the actual educational practices of liberal arts education. It is also significant in that it enables the observation and prediction of changes and trends in the research and actual fields of liberal arts education in the future.
Liver toxicity and DNA damage from exposure to the pesticide Mancozeb
Authors: Uribe Nelson D. Suarez , Pezzini Marina Ferri , Agnol Juliana Dall , Marroni Norma , Benitez Sandyelle , Benedetti Danieli , Silva Juliana Da , Cerski Carlos Thadeu , Dallegrave Eliane , Macedo Sandra , Joveleviths Dvora
Published: May 2023

Introduction: Brazilian agriculture has developed to such an extent in the last 40 years that the country will become one of the world’s largest food suppliers in the future. Indeed, to keep up this production, agriculture makes intensive use of fertilizers and agricultural pesticides, helping Brazil become one of the main pesticide consumers worldwide. Ethylenebisdithiocarbamates are a group of fungicides that have been widely utilized around the world, and Mancozeb is one of their main representatives. Therefore, a pilot experimental model was created to evaluate the potential hepatotoxic effect of Mancozeb. Materials and Methods: An experimental study was performed with 27 male Wistar rats, divided into 3 groups of 9 rats. Control Group received saline solution, Intervention Group I received 250 mg/kg once a week and Intervention Group II received 500 mg/kg also once a week. The treatment was performed for 12 weeks. Anthropometric measurements were performed and the marker of biological exposure in urine was dosed, biochemical tests, evaluation micronucleus count and comet assay, oxidative stress markers and histological assessment of the liver were done. Results: The hepatotoxic effect of exposure to Mancozeb was confirmed by different tests: anthropometric measures, genotoxicity, and oxidative stress. Statistical significance was found when exposed groups were compared to the control. These results were supported by microscopic evaluation of the liver tissue, where histological changes were found such as inflammatory infiltrate and balloonization in the treated groups. Conclusion: Experimental model was effective to demonstrate the deleterious effect on the liver due to exposure to Mancozeb.
Outpatient management of acute uncomplicated appendicitis after laparoscopic appendectomy
Authors: López Jordi Elvira
Published: May 2023

Objective: This manuscript is a mini review of the outpatient management of non-complicated acute appendicitis. We reviewed the literature supporting the safety and efficacy of outpatient management of laparoscopic appendectomy in adult patients with uncomplicated acute appendicitis.

Background Data: Outpatient laparoscopic appendectomy is feasible and safe in selected patients in observational studies. Benefits include reduced length of stay (LOS) and postoperative complications.

Data reported in 17 studies (mainly retrospective) suggested that outpatient appendectomy might be feasible. Several observational studies have shown that outpatient surgery is not associated with increased readmissions, increased morbidity rates, or reoperation. Until 2022, international guidelines supported the clinical efficacy and safety of outpatient appendectomy. However, the strength of the evidence is weak and recommendations cannot be given. In November 2022, the first randomized controlled trial (RCT) of outpatient treatment according to the ERAS protocol was published. In this study, the length of stay was significantly shorter. There were no differences in readmission rates. No further emergency consultations or complications were observed. The outpatient management had presented an economic saving.

Conclusion: Outpatient management of appendectomy is safe and feasible procedure in selected patients. This approach could become the standard of care for patients with uncomplicated appendicitis, showing fewer complications, lower LOS and cost.
Cognitive behavioral therapy for comorbid pediatric functional gastrointestinal disorders and anxiety: Systematic review and clinical applications
Authors: Korte Ciera , Friedberg Robert D.
Published: May 2023

Pediatric Functional Gastrointestinal Disorders (p-FGID) comprise one of the most common chronic conditions impacting global health. Conceptualized as gut-brain communication disorders, p-FGID are often exacerbated by and contribute to significant anxiety as well as functional impairment. Cognitive behavioral therapy is the gold standard psychosocial treatment for anxiety spectrum disorders. Prior research demonstrates a bidirectional link between p-FGID and anxiety symptoms, recommending CBT as the first line of treatment for both. While exposure is the potent ingredient for anxiety treatment, exposure is under-investigated in the treatment of p-FGID. The present brief systematic review synthesizes existent literature to describe the impact of CBT on p-FGID and anxiety symptoms in youth. The researchers systematically screened articles (n=23) located via Embase, Medline, and PsychINFO search. Eight studies meeting inclusion criteria were included for the final review. Three themes characterized the selected articles: (1) the impact of CBT on p-FGID symptoms, (2) the impact of CBT on health-related disability in youth with p-FGID, and (3) the impact of CBT on concurrent anxiety symptoms in youth with p-FGID. Key findings are summarized and implications for treatment are identified.
Investigation of urinary β2 microglobulin; substitute for interferon-γ as a suppressor of pulmonary fibrosis in a preterm with chronic lung disease following intrauterine infection
Authors: Nakamura Toshihiko , Kusakari Michiko , Ito Kana , Inoue Shota , Fukama Eisuke , Nomura Tomoaki , Hatanaka Daisuke , Takahashi Hidehiro
Published: May 2023

We experienced a female infant weighing 866 g at birth after 28 weeks 1 day gestation with apparent intrauterine infection. Bi-level-nasal CPAP was selected for respiratory management as a strategy to minimize the severity of chronic lung disease (CLD). As a result, she survived the acute phase without tracheal intubation and improved without requiring home oxygen therapy. Her urinary β2 microglobulin (u-BMG) in the early neonatal period was less than the cutoff value of 100,000 μg/gCr for the onset of CLD. However, her u-BMG then rose to a markedly high value that peaked at 3 weeks after birth. Her serum KL-6 was markedly high early after birth and increased sharply to a peak of 3016 U/mL on day 9. The increase in KL-6 in the early postnatal period indicated that lung tissue had already been injured by intrauterine inflammation, and although postnatal tracheal intubation was avoided, spontaneous breathing inevitably additionally injured the immature lung. It appears that substantial repair had occurred with fibrosis. It should be noted that the peak of u-BMG was delayed by more than 10 days from the peak of KL-6. This may suggest that the inflammatory cytokine interferon-γ, which increases the production of BMG, had not only an inflammatory effect that exacerbates lung damage, but also a biological self-defense effect that mainly suppresses lung fibrosis.
Congenital Cytomegalovirus screening in newborns: Current status in the United States
Authors: Nafday Suhas M
Published: May 2023

Targeted hearing screening for congenital cytomegalovirus (cCMV) with CMV polymerase chain reaction testing completed before 3 weeks of age for infants who fail newborn hearing screening is a reasonable option to improve cCMV related non-genetic sensory-neural hearing loss (SNHL). Universal cCMV screening using dried blood spots that is used on almost newborn infants has the potential to benefit those children at risk for SNHL and will be a great public health option.
EFFICIENT MATHEMATICS TEACHING AND DEFICIENT REQUIRED RESOURCES (A Case Study of District Panjgur)
Authors: Adam Khalid , Kiazai Abdul Nasir , Adam Shakir
Published: May 2023

The paper examines the relationship between efficient mathematics teaching and deficient required resources in district Panjgur, Balochistan.  In today's world of highly enhanced fields, especially in science and technology, it is impossible to march on the road of success in the absence of resources, commitment, dedication, and the urge to seek knowledge without any cultural or theological influence. The purpose of the paper is to highlight the factors which are hampering effective mathematics teaching in the high schools of the research area. In addition, it discusses the reasons for the failure of mathematics teachers in arranging the mathematical activities in the high schools in district Panjgur. Education is the most important factor for the progress and prosperity of any nation. Mathematics as a subject fascinated the mind and sharped analytical skills and vital for success of students in their future accomplishments. It plays a significant role as a subject for creating human resource, which are essential for the progress of any nation. The study has underlined the aspects which hinder the rapid up-gradation of mathematics as a subject and the traditional limitations associated with remote areas in classroom teaching.
EMPLOYEE’S JOB TURNOVER IN BANKING SECTOR AND ITS IMPACT ON SOCIETY AND POLICY FORMULATION
Authors: Tahir Khizar Hayat khan , Iqbal Athar , Bilal Muhammad
Published: May 2023

The aim of study is to carry out an analysis of determinants of employee’s job turnover in banking sector. Further possible impacts on society and policy formulation are discussed at the end. Empiric witness has been evaluated across three major determinants i.e., job involvement, organizational culture and compensation with employee’s job turnover. For analysis, the data was collected through a questionnaire from a sample of 200 bank employees (male n = 119 and female n = 81) out of the population of 2600 employees of three most of the banks of Pakistan as Habib Bank Limited, Allied Bank Limited and Askari Bank Limited. The classification has been done on the basis of the financial worth of the banks and the number of employees. The results confirm that the selected factors do have an impact on employee job turnover but other factors do matter. Out of these three factors job involvement had a negative impact on employee retention whereas the organizational culture and compensation had positive impacts on the turnover of employees.  The study is beneficial for employees and banks simultaneously. Policy implications are discussed in this paper.
FACTORS AFFECTING TO ACCEPT OR DENY THE COVID VACCINATION (A Comparative Study of Working and Non-Working Women During Pregnancy and Lactation)
Authors: Akmal Fozia , Siddiqui Faiza , Waheed Akmal
Published: May 2023

Every person is fighting the COVID-19 epidemic, the world's first and most potent danger of the twenty-first century. The whole world's attention is focused on the worldwide pandemic, and practically every nation is impacted in some way by it. Pregnant women are more prone than their nonpregnant counterparts to acquire a more severe case of COVID-19. Numerous factors argue in favour of the efficacy and safety of COVID-19 vaccines throughout pregnancy. According to research, between 29.7% and 77.4% of pregnant women got the COVID-19 vaccination. The study focused on analysis those factors which are responsible for creating perception about vaccination against COVID-19 disease. Whether pregnant and lactating women accept it or not. It also compared the decision of pregnant and lactating women respective to working and non-working women. The study suggested COVID-19 vaccination to protect pregnant women from severe sickness and death. Infants are at risk of developing problems linked with COVID-19, including respiratory arrest and other life-threatening consequences.
HEALTH INFORMATION SHARING ON FACEBOOK: AN EXPLORATORY STUDY ON COVID-19
Authors: Fatima Kiran
Published: May 2023

Social media is the most crucial part of our daily lives. Today the internet and World Wide Web are being used to influence people around the globe. However, the information available on social media struggles to maintain its credibility because anyone may upload content. Currently, it has been observed that Facebook being the biggest social media platform plays a significant role in the dissemination of information about the COVID-19 pandemic. The objective of this study was to investigate the information about COVID-19 on Pakistan's biggest page dedicated to COVID-19 known as Corona Recovered Warriors. The researcher conducted a qualitative and quantitative Facebook content analysis. The content was restricted to COVID-19 information available on the Corona Recovered Warriors Facebook page. The posts from June, September, and December were selected to analyze the change in themes of information over time. In Pakistan, in June, the highest number of daily COVID-19 positive cases are reported, September because of the ease in lockdown and the lowest number of COVID-19 daily cases, and then December when the graph of COVID-19 positive case again rises. A total of 28381 posts were analyzed in three months, and the focus of the posts was on Experience sharing (n=7934), Seeking or clarifying personal status (n=8419), Raising awareness on COVID-19 (n=2614), Support for patient and caregiver (n= 2597), and Product and service promotion (n=3341). A significant link between the number of posts on the Facebook page and the crucial and easy months related to COVID-19 positive cases has also been detected. COVID-19-positive patients and their relatives or family members share their health information widely with other Facebook users, also highlighting the need for collaboration between healthcare providers and media experts to design appropriate interventions for responding to pandemic diseases.