bluuebunny/crossref_metadata_2025 huggingface dataset:
Avoidant Pedagogy: Swiss and Israeli Teachers’ Handling of Religiously Offensive Remarks in Class
Authors: Gindi Shahar
Published: August 2024

The study examines teachers' positions when presented with a vignette regarding religiously offensive remarks. In-depth interviews were conducted with six Swiss and six Israeli female elementary school teachers. The findings demonstrated that teachers in both countries fluctuated between inclination to say that all opinions were acceptable, on the one hand, and drawing a line in the sand against religious intolerance, on the other. Only three teachers said that they would be clear that the remark in the vignette is prohibited. Teachers' dilemmas in the two countries were similar as were the strategies they chose. Teachers tended to flatten and oversimplify the discourse, considered students' subjective experience as indisputable, and avoided tackling prejudiced comments directly. Many teachers missed an opportunity to expose the power relations in society and to help develop students' critical thinking skills. Teachers' disbelief of students' remarks implies that many do not understand the way racism works or their role in preventing religious intolerance from an early age.
PERKEMBANGAN GERAKAN KEAGAMAAN DAN GLOBALISASI ISLAM SALAFI DI INDONESIA
Authors: AL-FARABI M.DZIKRI , TAUFIQ HISYAM , YUMITRO GONDA
Published: August 2024

Kaian ini mencoba mengkolaborasikan secara kritis islam salafi yang berkembang secara global dan transnasionalnya, gerakan dan kasus kasus spesifik di indonesia. tulisan ini berfokus pada bagaimana lembaga modernisasi gerakan pendidikan dan setrategi dakwah islam salafi dalam konteks global. Perannya dalam globalisasi salafi dan nilai nilai inti yang di ajarkan sehingga bertahan di tengah dampak globalisasi. Metode penelitian yang di gunakan dalam tulisan ini adalah studi budaya yang menggabungkan antara budaya local dan budaya asing dengan teknik kepustakaan. Teknik kepustakaan yang dimaksud untuk melakukan pencarian literatut literatu sebagai bahan pendukung baik berupa jurnal, skripsi, buku, serta perlengkapan asumsi atau fakta yang ada. Dalam batas tertentu dengan menerapkan teknologi informasi dan komunikasi modern untuk memperkenalkan dan menarik perhatian islam transnasional. Sejak awal hubungan antara pendidikan di indonesia dan pendidikan di timur tengah khusunya pendidikan di makkah dan madinah telah berkaitan sejak berdirinya lembaga tersebut. di lihat dari banyaknya warga indonesia melanjutkan untuk menempuh pendidikan di madinah dan makkah. Jika di pantau dari kaca mata budaya, nilai dan prinsip tradisional islam juga menjadi manifestasi dalam kehidupan sehari hari seperti pesantren terlepas dari kata globalisasi dan modernisasi.  Identitas seperti gaya hidup, berpakaian, makanan dan minuman, dan prilaku etis gerakan islam salafi . Secara tidak langsung kegigihan dari nilai nilainya terhadap modernisasi dan globalisasi. Pesantren  merepresentasikan posisi adaftif terhadap perubahan global dan tidak berdiri anti pemerintahan dan ikut andil dalam politik praktis. Kajian ini sengaja mengkolaborasikan asal usul dan pola globalisasi salafi di indonesia.
PENGARUH FATWA MAJELIS ULAMA INDONESIA NOMOR 44 TAHUN 2020 TERHADAP PEMBUATAN PRODUK POLITIK
Authors: Maulana Muhammad Asrul , Tsaqofah Islamiy Fahmiyah
Published: August 2024

Penelitian ini bertujuan untuk menganalisis pengaruh Fatwa MUI (Majelis Ulama Indonesia) terhadap pembuatan produk politik, salah satunya adalah Peraturan Daerah Kota Semarang Nomor 1 Tahun 2021 Tentang Produk Makanan Halal. Metode penelitian ini adalah normatif dengan pendekatan perundang-undangan (statute approach) dan pendekatan konseptual (conceptual approach). Hasil penelitian ini ditemukan Fatwa MUI No. 44/2020 berdampak pada produk politik dengan mempromosikan nilai-nilai Islam dan etika, mendorong transparansi serta kualitas program politik, serta mengingatkan pada pengawasan dan akuntabilitas. Peran masyarakat dalam pengawasan dan larangan klaim palsu dalam kampanye juga ditekankan. Secara keseluruhan, fatwa ini mengintegrasikan nilai agama, transparansi, dan partisipasi masyarakat dalam proses politik.
RASIONALITAS FORMULASI KEBIJAKAN PENATAAN DAERAH DAN ALOKASI KURSI PEMILIHAN UMUM ANGGOTA PARLEMEN
Authors: AGUS
Published: August 2024

Artikel ini bertujuan menjelaskan rasionalitas penyelenggara Pemilu dan pemangku kepentingan Pemilu dalam formulasi kebijakan penataan daerah pemilihan (Dapil) dan alokasi kursi untuk Pemilu anggota parlemen pada penyelenggaraan Pemilu 2024. Kajian difokuskan pada pendekatan tata kelola kebijakan, formulasi kebijakan dan pilihan kebijakan. Teori yang relevan menjelaskan fokus penelitian ini adalah teori collaborative governance dan teori formulasi kebijakan publik. Penelitian ini merupakan riset aksi, dimana peneliti terlibat langsung dalam formulasi kebijakan penataan Dapil sejak dari KPU Kabupaten dan Kota hingga KPU Provinsi di NTB melalui diskusi publik. Data dikumpulkan melalui wawancara, dokumentasi, kajian Pustaka, dan diskusi kelompok terumpun. Analisis data menggunakan pendekatan induktif secara linier dan hierarkis dari bawah ke atas dimulai dengan mengolah data, membaca data, menyusun coding data, memaknai data, menyusun narasi, diakhiri interpretasi data. Temuan penelitian menunjukkan tata kelola kebijakan penataan Dapil dan alokasi kursi anggota Parlemen dalam Pemilu 2024 menggunakan pendekatan kolaborasi model penta-helix.  Pendekatan tersebut melahirkan rumusan formulasi kebijakan penataan Dapil menjadi dua alternatif kebijakan yaitu kebijakan penataan Dapil model delapan Dapil dan kebijakan penataan Dapil model sepuluh Dapil. Pilihan kebijakan yang diambil oleh KPU RI sebagai pengambil kebijakan adalah alternatif kebijakan pertama dengan rasionalitas kebijakan penataan Dapil dan alokasi kursi berbasis pada tiga prinsip yakni: integralitas wilayah; kohesivitas; dan kesinambungan. Pada dasarnya pemangku kepentingan Pemilu sebagai aktor kolaborasi kebijakan mengharapkan KPU RI memilih alternatif kedua dengan rasionalitas kesetaraan nilai suara, ketaatan pada sistem pemilu proporsional daftar terbuka, proporsionalitas; dan berada dalam cakupan wilayah yang sama. Dengan demikian terjadi perbedaan rasionalitas penyelenggara dan pemangku kepentingan Pemilu dalam pilihan kebijakan penataan Dapil dan alokasi kursi anggota parlemen Pemilu 2024.
Borides as promising M2AX phase materials with high elastic modulus using machine learning and optimization
Authors: Mhadeshwar Ashwin , Mohanty Trupti , Sparks Taylor D.
Published: August 2024

There is growing interest in novel MAX phase materials for various applications ranging from aircraft/spacecraft and defense to energy and electronics due to their unique combination of metallic and ceramic properties. Traditional materials discovery has mostly relied on human intuition coupled with rigorous experiments; however, this approach has been time-consuming and inefficient. Over the last few decades, advances in fundamental and data-driven approaches such as first-principles modeling, materials informatics, machine learning and optimization, coupled with an exponential rise in computational power, have enabled faster and more efficient materials discovery. Here, we present an exploration of high elastic modulus novel boride-based M2AX phase materials using a combination of the aforementioned methods. Specifically, an ensemble of gradient boosted machine learning models was developed to predict the elastic modulus from informatics-based structural features by leveraging a dataset of Density Functional Theory (DFT)-predicted elastic moduli for 223 M2AX phase materials (carbides and nitrides). Using Bayesian optimization, inverse modeling was carried out to maximize the model-predicted elastic modulus by identifying the optimal features. Finally, model predictions for 1,035 candidate M2AX materials were generated to compare their features with the optimal features to identify potential novel promising materials. We found that Ta2PB, Nb2PB, and V2PB have similar high elastic moduli (371.7, 351.5, and 347.4 GPa) to their carbide counterparts (364.7, 357.7, and 373.5 GPa), and our results support the possibility that borides can be a viable tertiary element for M2AX phases.
Perilaku Shearwall Pelat Bergelombang Terhadap Beban Gempa Lateral Statik
Authors: Darmawan Arya Rizki , Mayawati Sari , Jumri Jumri
Published: August 2024

Portal bangunan gedung dengan konstruksi baja profil sudah sangat umum digunakan. Namun dengan potensi gempa di Indonesia yang memiliki resiko sangat besar, maka geometri portal harus diberikan elemen struktur yang dapat meningkatkan kekakuan lateral dari struktur tersebut. Salah satu inovasi untuk meningkatkan kekakuan lateral dari portal bangunan gedung adalah dengan memberikan elemen struktur berupa shearwall. Shearwall pelat baja adalah salah satu elemen struktur yang berfungsi untuk menahan beban lateral pada suatu bangunan, salah satunya adalah beban gempa. Shearwall pelat baja memiliki angka kelangsingan yang tinggi. Sehingga beban lateral akan mengakibatkan masalah tekuk yang besar pada pelat shearwall. Pelat baja bergelombang adalah salah satu inovasi untuk menyelesaikan permasalahan tekuk tersebut. Tujuan penelitian ini adalah untuk menganalisa efek dari bentuk pelat gelombang pada shearwall. Penelitian ini dilakukan dengan cara analisa numerik menggunakan program bantu ANSYS untuk melihat perilaku dan kekuatan dari shearwall pelat baja. Permodelan shearwall yang dianalisis adalah dengan tipe beam column frame, shearwall dengan pelat baja datar, dan shearwall dengan pelat baja bergelombang yang diberikan beban lateral statik pada salah satu ujungnya. Penelitian ini menunjukkan beban leleh pada beam column frame sebesar 1400 kN, shearwall pelat baja datar sebesar 1850 kN, dan shearwall pelat baja bergelombang sebesar 2035 kN. Dengan dibuatnya pola geometri pelat bergelombang didapat peningkatan beban leleh 9% dibandingkan dengan pelat datar. Pola tekuk yang terjadi pada shearwall pelat datar dan pelat gelombang adalah tekuk geser diagonal di area tengah pelat.
ANALISIS EFEKTIFITAS MARKA YELLOW BOX JUNCTION PADA SIMPANG TIGA AHMAD YANI KM 3 KOTA BANJARMASIN
Authors: Hardiani Dyah Pradhitya , Ruhaidani Emma
Published: August 2024

Kalimantan Selatan merupakan salah satu Provinsi yang memiliki jumlah penduduk cukup besar. Menurut Badan Pusat Statistik (2023) jumlah penduduk Kota Banjarmasin tahun 2022 mengalami peningkatan sebesar 1,51 %. Bertambahnya jumlah penduduk mengakibatkan tingginya nilai pengguna jalan, sehingga berdampak pada masalah transportasi seperti kemacetan salah satunya Simpang Tiga Ahmad Yani Km 3. Kemacetan di daerah tersebut merupakan kejadian yang sering terjadi, karena merupakan akses untuk menuju pusat kegiatan masyarakat kota Banjarmasin. Usaha yang dilakukan pemerintah untuk mengendalikan kemacetan yaitu dengan menggunakan marka Yellow Box Junction. Penelitian ini bertujan untuk mengetahui kesesuaian dan efektifitas marka Yellow Box Junction. Parameter yang digunakan untuk mengetahui efektifitas ditinjau dari jumlah pelanggar marka dan nilai derajat kejenuhan. Hasil penelitian didapatkan bahwa kinerja simpang pada Simpang Tiga Ahamad Yani KM 3 Kota Banjarmasin tidak efektif dikarenakan nilai DS melebihi nilai yang ditentukan dalam MKJI 1997 yaitu >0,85. Dari hasil presentase pelanggar, disimpulkan bahwa marka Yellow Box Junction tersebut termasuk kategori sangat efektif seperti pada Traffic Utara didapatkan nilai rata – rata efektifitas sebesar 92,34%, pada Traffic Timur didapatkan nilai rata-rata efektifitas sebesar 89,71%. Hasil pengamatan kesesuaian marka Yellow Box Junction pada Simpang Tiga Ahmad Yani KM 3 Kota Banjarmasin dengan standar yang berlaku menunjukkan hasil tidak sesuai dengan ukuran marka Yellow Box Junction pada lebar garis lurus dan lebar garis diagonal sebesar 30 cm.
ANALISIS METODE PELAKSANAAN COR BERTAHAP PRECAST PADA PENYELESAIAN PROYEK OVERPASS PT. TALENTA BUMI MARABAHAN STUDI KASUS PADA PROYEK OVERPASS – MARABAHAN
Authors: Harto Hanung Budi
Published: August 2024

The precast method work is adjusted because the slab elevation is ± 7 meters high, so it takes a lot of scaffolding (material) and time. Determination of precast concrete is done by analyzing preliminary design calculations, precast loading calculations, evaluating the load to be lifted, in the form of precast self-load, for precast concrete lifting time, precast concrete reinforcement, scaffolding calculations against precast self-load. Based on the results of the study for the age of 1 day concrete for the lifting permit of K-35 tons crane more than the precast load, then the load can be carried by the crane. But in the cylinder validation test, the value is obtained on the first day, so the work can be done earlier. As for the top cast with insitu cast method using the coefficient on day 3 with a value of 0.4, the comparative value of Mu = 30.893 tons.m and Mr = 31.877 tons.m according to the cylinder validation test graph with fc' 12 MPa, the work was obtained on day 2 and because the concreting was carried out in the fastest time of 1 day, the casting could be done on day 3 where the quality of concrete compressive strength has met according to PBI'71 regulations.
The Use of Water Hyacinth Leaves Supplementation in Ruminant Feed on Methane, Protozoa, VFAs and Fatty Acids Ruminal Fluid in Vitro
Authors: Sondakh Erwin Hubert Barton , Kalele Jerry , Tuwaidan Nancy
Published: August 2024

This study aims to determine the effect of water hyacinth leaves supplementation in ruminant feed parameters of fermentation, and fatty acids ruminal fluid in vitro. The experiment consists of six treatments, R0: no water hyacinth + 30% concentrate; R1: 1% water hyacinth leaves + 29% concentrate; R2: 2% water hyacinth leaves + 28%; R3: 3% water hyacinth leaves + 27% water hyacinth leaves; R4: 4% water hyacinth leaves + 26% concentrate; R5: 5% water hyacinth leaves + 25% concentrate.  The fermentation was conducted at 39oC for 72 hours using gas production technique. The results indicated that giving of 4% water hyacinth leaves and 26% concentrate of MCFA could reduce the number of protozoa and methane production (P<0.05) and increase propionate acid. It can be concluded that use of 4% water hyacinth leaves and 26% concentrate could reduce methane gas production and quantity of protozoa and also could increase propionate acid in rumen fermentation in vitro.
The Rule of Reason Approach in Discriminatory Practices: Airlines and Telecommunications Industry Sector
Authors: Abrianti Sharda , Maria Tri Anggraini Anna , Sabirin Ahmad , Chintya Mardohar Joice , Fernandez Séréna Ortigosa
Published: August 2024

Discriminatory practices are standard in business competition and are not prohibited as long as they do not cause unfair competition. This paper will discuss three Business Competition Supervisory Commission (KPPU) decisions in 2020 related to alleged discriminatory practices committed by business actors. The subject matter in this paper is how the actions of business actors can fulfil the elements of violation and how the application of the rule of reason approach in Article 19 letter d of the Competition Law (1999) in the 2020 KPPU Decisions. This research is descriptive normative research. The data used in the book, articles, the new paper analyzed the Competition Law (1999), the Airlanes law (2009), the Electronic Information and Transactions Law (2008, amendments 2016 & 2024), and the Hajj and Umarah Law (2019), as well as interview an expert and KPPU. The interesting findings found that acts of discrimination cause obstacles in vertical business relations in different but interrelated relevant markets and often occur in the essential facilities sector. By using the rule of reason approach, KPPU found that discriminatory practices will be more effective if the business actor is in a dominant position or even occupies a monopoly position. Then, the three decisions in this discussion are equally suspected of violating Article 19 letter d on discriminatory practices. Then, related to the relevant market, the three cases have different markets, and also all three have vertical relationships with other business actors.
Unveiling the Legal Impacts: The Unilateral Termination of the 1997 Russian-Ukrainian Friendship Treaty
Authors: Gunawan Yordan , Riyanto Aisyah Ajeng Putri , Farman Logi
Published: August 2024

In 2022, Russian forces seized the capital of Ukraine, Kyiv, and reported more than 700 attacks on health facilities, personnel, and transport vehicles, resulting in the deaths of over 200 people. Despite encountering complex issues, Ukraine and Russia concluded the 1997 Russian-Ukrainian Friendship Treaty, which addressed matters of equality, sovereignty, and territorial integrity. However, Ukraine unilaterally terminated the Treaty in 2018. This research aims to analyze the legal implications arising from the unilateral termination of the Treaty, focusing on the realm of international law. The research employs a combination of normative legal research, analytical conceptual approaches, and case studies. The findings indicate that the termination of the Treaty adhered to Article 54(a) of the Vienna Convention on the Law of Treaties 1969. Nevertheless, the termination has resulted in legal uncertainty and has the potential to exacerbate pre-existing tensions, particularly regarding territorial integrity, which have intensified since 2014.
Ketika Animasi Menjadi Soft Diplomacy: Bagaimana Animasi Mengkonstruksikan Nilai-Nilai Pancasila?
Authors: Wikayanto Andrian , Ocktaviana Sentiela , Pradipta Lengga
Published: August 2024

The increasing number of conflicts and hatred narrations that spread on online and offline media motivate local filmmakers to make animations that present Pancasila, one of which is the animated series Adit Sopo Jarwo (ASJ) which can be accessed freely on YouTube. This study is to analyze how Pancasila's values are communicated through animation works. This study uses a qualitative content analysis method. Qualitative content analysis emphasizes text and symbols in a particular context. The coding process is carried out using NVivo 12 plus by examining the Pancasila values' distribution through two variables, animation elements (audio, motion, narrative, and visual) and the characters in the series. The data were collected by identifying the Pancasila values that appeared in the ASJ series: religion-tolerance, humanity; patriotism-unity; democracy; and social justice. Those values are articulated in this animation work through animation basic elements and characters. Animated series not only can be used as entertainment media but also can be used by creators as soft diplomacy tools to convey the values of Pancasila
Digital Literacy and Islamic Sharia Values as A New Perspective of Preventing OGBV
Authors: Fitri Ainal , Triantoro Dony Arung , Nurrahmi Febri , Haekal Muhammad
Published: August 2024

This research aims to explore the digital literacy position of students using social media in Aceh and see its relation to the issue of OGBV as victims and bystanders. This research also investigates the relationship between digital literacy, OGBV, and the role of Sharia Law in Aceh, which may provide a new perspective for preventing OGBV in Indonesia, considering the paucity of previous studies correlating those three aspects. This research utilized the concept of Digital Literacy created by Paul Gilster and used the Four-Component Digital Literacy Model developed by Alexander V. Sharikov. This research was conducted using a qualitative approach. Researchers conducted in-depth interviews with nine students and analyzed them using Thematic Analysis. The results revealed that most participants do not have a knowledge base about OGBV, which has implications for their digital literacy capital, especially in identifying various OGBV variants and how to protect personal data on social media. In addition, Islamic law influences participants' digital literacy in dealing with OGBV. However, participants' knowledge of Sharia law values regarding safe and responsible digital interaction patterns has yet to develop comprehensively.
Disaster Communication and Civic Voluntarism during COVID-19 Pandemic: The Case of Bandung
Authors: Ismail Oki Achmad , Wijaksono Dimas Satrio
Published: August 2024

This research examined communication strategies in increasing volunteer participation and communication methods in improving disaster communication skills. This research also identified challenges and obstacles in implementing civic voluntarism in the city of Bandung. This research used a qualitative method with a case study approach at the Bandung City Fire and Disaster Management Service. Data was collected through interviews, documents, observations and literature studies. The research results show that the people of Bandung City have a movement based on civic voluntarism in dealing with Covid 19. Technical guidance is used to encourage civic voluntarism. Technical guidance is used to train skilled volunteers in carrying out disaster communications. By having knowledge, reliability and communication skills, volunteers become one of the strengths of disaster communication in the city of Bandung. There are three main obstacles in its implementation, namely differences in education level, motivation and time availability among volunteers.
Ibu(isme) dan Film Orde Baru: Representasi Ibu dalam film Jangan Menangis Mama
Authors: Kurnia Novi , Hidayatullah Mochammad Taufik
Published: August 2024

The representation of women in films is always an interesting topic in Indonesian film studies. This article aims to reveal the representation of women, especially in their identity as mothers in the film Jangan Menangis Mama (Don’t Cry Mommy) was produced in 1977. This film was directed by Sofia WD, a film star, screenwriter, and film producer who works both in the Old Order and the New Order of the Indonesian Film Industry. Based on Roland Barthes' semiotic analysis, this article uncovers two levels of meaning systems, namely denotation and connotation related to the mother's character in the film. The process of interpreting these signs cannot be separated from the concept of ‘ibuism’ (motherhood) as a gender-political ideology of the New Order and the context of the male-dominated film industry. Research findings show that the dominant representation of mothers is associated with the weak position of a woman with various roles: as a wife, a mother, a single mother, a citizen, and a daughter. However, this research found a 'limited' agency from Sofia WD as a woman director of the film Jangan Menangis Mama to offer gender representation that is not completely stereotypical as well as not just 'black and white' as in previous studies.
PERAN BECAK TRADISIONAL DALAM MENDUKUNG PARIWISATA DI KAWASAN MALIOBORO YOGYAKARTA
Authors: Haryanto Laurensius Windy , Almira Rahmania , Harseno Ahmad Rieskha
Published: August 2024

Di masa perkembangan zaman yang semakin modern ini, Kota Yogyakarta berkembang dengan mempertahankan nilai kebudayaan dan kesejarahan yang dimiliki sebagai identitas daerah. Identitas tersebut menjadikan Kota Yogyakarta memiliki daya tarik wisata baik oleh wisatawan domestik maupun internasional. Salah satu warisan budaya di bidang transportasi yang masih ada di Kota Yogyakarta adalah becak tradisional. Di era perkembangan teknologi yang pesat, becak tradisional masih menjadi sumber mata pencaharian utama bagi sebagian besar pengemudi becak. Dalam mewujudkan upaya pelestarian, kini becak tradisional dimanfaatkan sebagai transportasi alternatif pendukung pariwisata di Kota Yogyakarta. Berlandaskan hal tersebut, maka penelitian ini membahas peran becak dalam meningkatkan potensi wisata di Kota Yogyakarta, khususnya kawasan wisata Malioboro dan berbagai faktor pendukungnya. Penelitian menggunakan pendekatan kualitatif dengan perolehan data melalui observasi dan wawancara secara purposive sampling. Hasil penelitian ini menemukan bahwa becak tradisional menjadi sarana yang mampu memperkenalkan berbagai tempat wisata di Kota Yogyakarta dan promosi berbagai pelaku usaha yang berada di kawasan Malioboro.
Penentuan Lokasi Pusat Distribusi Alternatif Gudang Beras di Kerisedenan Surakarta melalui Pendekatan Metode Center of Gravity
Authors: Winoto Erwin Shafira , Arifin Miftahol
Published: August 2024

Dalam era globalisasi dan persaingan bisnis yang semakin ketat, manajemen rantai pasokan dan distribusi menjadi faktor kunci dalam kesuksesan suatu perusahaan. Penelitian ini bertujuan untuk mengoptimalkan lokasi pusat distribusi alternatif di Kerisidenan Surakarta, sebuah wilayah yang penting dalam pasokan beras di Jawa Tengah, Indonesia. Metode Center of Gravity digunakan sebagai alat analisis utama dalam penelitian ini. Metode ini memungkinkan identifikasi lokasi pusat distribusi yang optimal berdasarkan koordinat geografis konsumen dan jumlah permintaan mereka. Dengan memanfaatkan data permintaan beras konsumen dari daerah Boyolali, Karanganyar, Sragen, Wonogiri, Sukoharjo, Surakarta, dan Klaten, penelitian ini menghasilkan lokasi pusat distribusi yang dapat meminimalkan biaya transportasi dan mempersingkat waktu pengiriman. Selain itu, penelitian ini juga mempertimbangkan aspek keberlanjutan dalam pemilihan lokasi pusat distribusi. Keberlanjutan merupakan isu yang semakin penting dalam lingkup global, dan pemilihan lokasi yang mendukung pengurangan emisi karbon dan efisiensi energi menjadi bagian integral dari penelitian ini. Hasil penelitian ini adalah pemilihan lokasi pusat distribusi alternatif yang akan membantu perusahaan, dalam hal ini PT ABC, untuk meningkatkan efisiensi distribusi beras di wilayah Kerisidenan Surakarta. Dengan lokasi yang optimal, perusahaan dapat memenuhi permintaan konsumen dengan lebih baik, mengurangi biaya distribusi, dan memainkan peran dalam mendukung tujuan keberlanjutan global. Penelitian ini memberikan panduan yang berharga bagi perusahaan dalam manajemen rantai pasokan dan distribusi yang efisien dan berkelanjutan.
Smart Monitoring System Pada Pembudidayaan Jamur Tiram Menggunakan Metode Fuzzy Logic
Authors: Basirun Arif Reza , Anggraini Violita , Al Kautsar Muhammad Nurudduja
Published: August 2024

Mushrooms, which are known as food commodities, when cultivated require temperatures between 22-28°C and humidity of 60-80%. Controlling these two factors is very crucial, especially when weather fluctuations occur throughout the day. As a solution, an artificial intelligence-based system was introduced to regulate temperature and humidity. The "fuzzy control" technique in artificial intelligence is an option because of its flexibility and convenience without involving complex mathematical calculations. The Fuzzy Mamdani method is one approach to "fuzzy control" which allows automatic control of temperature and humidity in mushroom cultivation areas. To apply this method, sensors are needed that can provide data to the fuzzy system. This fuzzy system works in four steps: fuzzification, rule determination, inference, and defuzzification. Based on the results of comparative tests with MATLAB software, there is a correctness level of around 26% in the measurement results.
A Penerapan Metode Analytical Network Process (ANP) Dalam Pemilihan Supplier Telur di UMKM Ibu Wari
Authors: Qomariyah Darul , Ningrum Amelia Septia , Winoto Erwin Shafira
Published: August 2024

UMKM berperan penting dalam perekonomian global maupun lokal, sehingga harus mampu mempertahankan kualitas produk dan bersaing dengan meningkatkan penjualan produk. UMKM menjadi sarana pemenuhan kebutuhan sehari-hari masyarakat, salah satunya adalah bahan pangan telur. Toko Ibu Wari menjadi salah satu UMKM yang menyediakan telur untuk memenuhi permintaan masyarakat sehari-hari. Untuk memenuhi permintaan tersebut maka perlu diperhatikan ketersediaan stok dan kualitas telur di toko. Sehingga oleh karena itu, penelitian ini dilakukan dengan tujuan untuk menentukan supplier telur berdasarkan kriteria yang paling berpengaruh dan urutan pemilihan supplier telur tersebut. Permasalahan tersebut diselesaikan menggunakan metode Analytical Network Process (ANP) dengan bantuan software Super Decision. Berdasarkan hasil pengolahan data yang telah dilakukan, kriteria cost paling berpengaruh dalam pemilihan supplier dengan bobot kriteria sebesar 0,194409. Urutan pemilihan supplier berdasarkan penilaian kinerja supplier adalah supplier A, C, dan B.
Cardiac Rehabilitation for Fontan Circulation Patients: A Systematic Review, and Meta-Analysis
Authors: de Ven Luna Van , Félix Ana Clara , Suarez Joana , Dias Jorge , Pinto Fatima F. , Laranjo Sérgio
Published: August 2024

Background: Despite procedural advancements in the management of univentricular heart patients palliated with a Fontan-type circulation, their exercise capacity and quality of life remain limited. Postoperative exercise training programs offer potential benefits, yet practical implementation and adherence to guidelines are often inadequate. This systematic review and meta-analysis aimed to evaluate the safety, efficacy, and optimal exercise modalities for Fontan patients. Method: A systematic search was conducted on August 24, 2023, using PubMed, Scopus, Web of Science, and Cochrane Library. Studies were screened via Rayyan QCRI based on pre-set exclusion criteria, and their quality was assessed using the Cochrane RoB Tool 2 and the STROBE checklist. A meta-analysis employed a continuous random-effects model to assess the efficacy of cardiac rehabilitation interventions. Results: The study included twenty-six studies (7 RCTs, 19 cohorts) representing 22 individual cohorts. The key findings were that aerobic exercise, lower-extremity resistance training, and inspiratory muscle training significantly improved VO2, enhancing exercise capacity in Fontan patients. Conclusion: While the results are promising, it's crucial to remember that training programs varied widely. Exercise training shows promise for postoperative management, potentially improving exercise capacity, cardiac biomarkers, lung function, and lower limb strength. However, further research is not just a suggestion, but a necessity. It's necessary to refine protocols, assess long-term impacts, and investigate underlying mechanisms, especially for Fontan patients with severe clinical conditions. This emphasizes the importance and urgency of further research in this area.
Monitoring the Net Primary Productivity of Togo's Ecosystems in Relation to Changes in Precipitation and Temperature
Authors: BADJARE Bilouktime , Folega Fousseni , BAWA Demirel Maza-esso , Weiguo Liu , Hua Guo Huang , Wala Kperkouma , Batawila Komlan
Published: August 2024

Climate variability influences plant growth. With the variation in atmospheric CO2 concentration leading to global warming, it is urgent to monitor the performance of plant ecosystems for optimal carbon sequestration. Net primary productivity (NPP) is the perfect measurement tool as it measures the net carbon flux between the atmosphere and green plants and the factors that affect it. This study applied remote sensing techniques, specifically one of the radiation use efficiency models; the CASA model (Carnegie-Ames-Stanford approach) to assess the spatio-temporal dy-namics of NPP in Togo from 1987 to 2022 and the climatic parameters that influence it. The annual average NPP over the 36 years of the study is 4565.31 Kg C ha⁻¹. Variability is observed over the years with extremes in 2017 (6312.26 Kg C ha⁻¹) and 1996 (3394.29 Kg C ha⁻¹). Natural formations identified as high-production areas saw their productivity increase between 2000 and 2022. The interaction between climate change and land use changes negatively influences the variation of Total Production (PT) between 2000 and 2022, while individually, these parameters positively influence the variation of NPP (58.28% and 188.63%). The correlation result is positive and higher between NPP and light use efficiency (LUE) (r² = 0.75). Actual evapotranspiration also shows a positive correlation with NPP (r² = 0.43). A positive but weak correlation is observed between NPP and precipitation, potential evapotranspiration (r² = 0.20; 0.10 respectively). Temperatures have almost no correlation with NPP (r² = 0.5). Climatic parameters as a whole under the LUE banner influence NPP more. This study helps understand ecosystem performance in the context of To-go's commitments to reduce greenhouse gas emissions and combat climate change.
Comparative Molecular Docking of Apigenin and Luteolin Versus Conventional Ligands for TP-53, pRb, APOBEC3H, and HPV-16 E6: Potential Clinical Applications in Preventing Gy-necological Malignancies
Authors: Dunjic Momir , Turini Stefano , Nejkovic Lazar , Sulovic Nenad , Cvetkovic Sasa , Dunjic Marija , Dunjic Katarina , Dolovac Dina
Published: August 2024

This study presents a detailed comparative analysis of Molecular Docking data, focusing on the binding interactions of conventional ligands and natural compounds, Apigenin and Luteolin, with TP-53, pRb, and APOBEC. Utilizing advanced bioinformatics techniques, coupled with Ar-tificial Intelligence software and High-Performance Computing (HPC), we measured and con-trasted the binding energies of these interactions. Additionally, we investigated protein-protein interactions between HPV-16 oncoprotein E6 and tumor suppressors TP-53 and pRb. Our findings demonstrate that the natural compounds Apigenin and Luteolin exhibit significantly higher binding affinities to TP-53, pRb, and APOBEC compared to conventional pharmacological ligands. The binding energies for Apigenin and Luteolin were approximately -6.9 kcal/mol and -6.6 kcal/mol, respectively, indicating their strong potential as therapeutic agents in inhibiting the oncogenic functions of HPV-16. In contrast, conventional ligands showed lower binding affinities, with energies around -4.5 to -5.5 kcal/mol. The study further revealed that the protein-protein interactions between E6 and TP-53, and E6 and pRb, exhibited considerably higher binding en-ergies, approximately -976.7 kcal/mol, due to the multiple interaction sites and the complex nature of protein interfaces. A conversion formula was developed to translate these high-energy inter-actions to a comparable scale for non-protein-protein interactions, highlighting the superior binding potential of natural compounds, which, through the same conversion formula, was shown to be higher than that of interaction between E6 with TP-53 and E6 with pRb. These results underscore the therapeutic promise of Apigenin and Luteolin in preventing HPV-16-related on-cogenesis. By demonstrating their higher binding affinities to crucial tumor suppressors, this study supports the development of natural compound-based therapies. The findings also em-phasize the necessity for further experimental validation to explore these compounds' efficacy in clinical settings. This comprehensive analysis provides a robust framework for understanding the comparative binding interactions and lays the groundwork for innovative therapeutic strategies against HPV-16.
NT-proBNP as a Biomarker of Endotheliopathy in Pediatric and Young Adult Hematopoietic Stem Cell Transplantation
Authors: Uchida Kimberly , Yuan Xiaomeng , McArthur Jennifer , Lassiter Rebekah , Pan Haitao , Keerthi Dinesh , Tsai Katherine , Avent Yvonne , Hines Melissa , Martinez Hugo R. , Qudeimat Amr , Ghafoor Saad
Published: August 2024

Background/Objectives: Hematopoietic stem cell transplantation (HSCT) in pediatric and young adult (YA) patients can lead to endotheliopathy, such as thrombotic microangiopathy (TMA), sinusoidal obstruction syndrome (SOS), and diffuse alveolar hemorrhage (DAH). Natriuretic peptides have been studied as markers of endotheliopathy and critical illness. We hypothesized that elevation in NT-proBNP was associated with development of endotheliopathy (DAH, SOS, or TMA) in the first 100 days following HSCT in pediatric and YA patients. Methods: IRB exempt status was obtained. This retrospective case-control study reviewed HSCT at our institution from 2016-2020. Cases were selected based on an endotheliopathy diagnosis in the first 100 days after HSCT. Cases were matched with controls. Baseline and near-event NT-proBNP levels were compared between cases and matched controls. Effect of NT-proBNP levels on developing endotheliopathy was estimated using conditional logistic regression. Results: Sixty-two patients were included (31 cases, 31 controls). Near-event NT-proBNP was significantly higher in cases compared to controls (Median: 473 vs. 187 pg/mL, p = 0.03, Wilcoxon rank-sum test), in contrast to comparison in baseline NT-proBNP (Median: 86 vs. 86 pg/mL, p = 0.51). After adjusting for co-variates, association between near-event NT-proBNP and odds of developing endotheliopathy did not achieve statistical significance. However, trends from most common transplant indications suggested an association between elevated near-event NT-proBNP level and endotheliopathy, particularly in acute lymphoblastic leukemia (ALL) patients. Conclusions: NT-proBNP should be studied further as a biomarker for endotheliopathy in pediatric and YA patients undergoing HSCT. This may be particularly relevant for patients undergoing HSCT for ALL.
Resilient Coping Levels and Psychometric Properties of the Brief Resilient
Coping Scale among Nursing Professionals in Saudi Arabia
Authors: Albougami Abdulrhman
Published: August 2024

This cross-sectional survey assessed the resilient coping levels and their relationship with the socio-demographic characteristics of nursing professionals in Saudi Arabia. Adult (≥18 years) registered nurses and practicing for ≥1 year were included. Resilient coping levels (as assessed via a 4-item Brief Resilience Coping Scale; BRCS) and socio-demographic and other characteristics data were collected. Descriptive analysis and ordinal logistic regressions were used to analyze the data. Further, the psychometric properties of the BRCS were reported. A total of 216 nursing professionals were included. The mean BRCS score was 14.6 (standard deviation=3.6), with most nursing professionals (62.5%) reporting medium to high resilience coping levels. The ordinal logistic regression model demonstrated that increasing age (p=0.002), best overall health (p=0.001), and nurses posted in the outpatient department (p=0.049) and intensive care unit (p=0.032) had significantly high resilient coping levels. The internal consistency of the BRCS was good (Cronbach’s alpha=0.80). In summary, nursing professionals in Saudi Arabia showed medium resilient coping levels. Moreover, this study suggests that BRCS is a psychometrically reliable and adequate tool for assessing resilience coping levels and provides valuable insights into the relationship between resilient coping levels and socio-demographic characteristics of the nursing professionals in Saudi Arabia.
Viability of Spider Silk Proteins in Scaffolds for Tissue Engineering
Authors: Varikuti Akhil Reddy
Published: August 2024

Spider silks, renowned for their exceptional mechanical and biocompatible properties, offer significant potential as scaffolds in tissue engineering. This paper explores the feasibility of using spidroins, the primary proteins in spider silk, to develop scaffolds that closely mimic the extracellular matrix (ECM) essential for tissue regeneration. Spidroins (spider silk proteins) are particularly valuable due to their unique strength, elasticity, and biocompatibility, which support cellular growth and differentiation. The paper examines current methods for producing recombinant spider silk, including using unicellular hosts like E. coli and multicellular systems like transgenic plants and silkworms. It also examines current scaffolds that utilize spidroins and their shortcomings, such as immunogenicity and protein production, which must be urgently addressed for more practical and effective widespread biomedical applications. In addition, it stresses the need for further research to solve these challenges and fully realize the potential of spider silk in biomedical applications.
LGALS9, LAMP3, PRSS8 and AGRN Predict Hospitalisation Risk in COVID-19 Patients
Authors: McLarnon Thomas , McDaid Darren , Lynch Seodhna M. , Cooper Eamonn , McLaughlin Joseph , McGilligan Victoria E. , Watterson Steven , Shukla Priyank , Zhang Shu-Dong , Bucholc Magda , English Andrew , Peace Aaron , O'Kane Maurice , Kelly Martin , Bhavsar Manav , Murray Elaine K. , Gibson David S. , Walsh Colum P. , Bjourson Anthony J. , Rai Taranjit Singh
Published: August 2024

Background: The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2 has posed unprecedented challenges to healthcare systems worldwide. Here, we have identified proteomic and genetic signatures for improved prognosis which is vital for COVID-19 research. Methods: We investigated the proteomic and genomic profile of COVID-19 positive patients (n=400 for proteomics, n=483 for genomics), focusing on differential regulation between hospitalised and non-hospitalised COVID-19 patients. Signatures had their predictive capabilities tested using independent machine learning models such as Support Vector Machine (SVM), Random Forest (RF) and Logistic Regression (LR). Results: This study has identified 224 differentially expressed proteins in hospitalised COVID-19 patients compared to non-hospitalised COVID-19 patients, involved in various inflammatory and immunological pathways. LGALS9 (p-value < 0.001), LAMP3 (p-value < 0.001), PRSS8 (p-value < 0.001) and AGRN (p-value < 0.001), were identified as the most statistically significant proteins. Several hundred rsIDs were queried across the top 10 significant signatures, identifying three significant SNPs on the FSTL3 gene showing correlation with hospitalisation status. Conclusion: Our study has not only identified key signatures of COVID-19 patients with worsened health but has also demonstrated their predictive capabilities as potential biomarkers, which suggests a staple role in the worsened health effects caused by COVID-19.
Lipopeptides Produced by Bacillus spp.: Detection of Genes and Meta-analysis of Their Activity Against Phytopathogenic Fungi
Authors: Cob-Calan Nubia Noemi , Cua-Basulto Marcos Enrique , Hernández-Montiel Wilber , Us-Camas Rosa Yazmin , Reyes-Ramírez Arturo , Dzib-Cauich Dany A. , Cristóbal-Alejo Jairo , Sanchez-Ruiz Esau , Hernández-Núñez Emanuel
Published: August 2024

Lipopeptides are bioactive compounds produced by Bacillus spp. This work provides insight into de antifungal activity of lipopeptides through a meta-analysis of published studies, in addition following PCR (polymerase chain reaction) technique, the presence of lipopeptides genes in 20 Bacillus strains were also analyzed. The meta-analysis of published studies showed that iturin, fengycin and surfactin significantly reduced the growth of phytopathogenic fungi. Similarly, when applied to plant tissues, the lipopeptides reduced the severity of damage in plant tissues caused by phytopathogenic fungi. As for the lipopeptides genes detection, we used 20 Bacillus strains reported to have antagonistic activity against various fungal plant pathogens. The PCR amplification study was carried out to detect the genes involved in the synthesis of lipopeptides: ituA for iturin A, fenD for fengycin and srfA for surfactin. Comparative sequence analysis showed a range of 98 to 100% identity with the corresponding genes in several Bacillus species. We observed at least one Bacillus gene in the strains: CBRF5, CBRF15, CBSN67, and CBRM9. In the strain CBRF6, we detected the presence of the fabD and srfAD genes. For the development of natural fungicides to control phytopathogenic fungi, lipopeptides produced by Bacillus spp. could be a useful tool.
Novel Metabolites Associated with Decreased Gfr: A 12-Year Follow-Up of the METSIM Cohort
Authors: Fernandes Silva Lilian , Vangipurapu Jagadish , Oravilahti Anniina , Laakso Markku
Published: August 2024

Identification of the individuals having impaired kidney function is essential in preventing the complications of this disease. We measured 1 009 metabolites at the baseline study in 10 159 Finnish men of the METSIM cohort and associated the metabolites with estimated glomerular filtration rate (eGFR). A total of 7 090 men participated in the 12-year follow-up study. Non-targeted metabolomics profiling was performed at Metabolon, Inc. (Morrisville, NC, USA) on EDTA plasma samples obtained after overnight fasting. We applied Liquid chromatography-mass spectrometry (LC-MS/MS) to identify the metabolites (the Metabolon DiscoveryHD4 platform). We performed association analyses between the eGFR and metabolites using linear regression adjusted for confounding factors. We found 108 metabolites significantly associated with a decrease in eGFR, and 28 of them were novel including 12 amino acids, 8 xenobiotics, 5 lipids, 1 nucleotide, 1 peptide, and 1 partially characterized molecule. The most significant associations were with five amino acids, N-acetylmethionine, N-acetylvaline, gamma-carboxyglutamate, 3-methylglutaryl-carnitine, and pro-line. We identified 28 novel metabolites associated with decreased eGFR in the 12-year follow-up study of the METSIM cohort.
Predicting Catheter-Associated Urinary Tract Infections and Antibiotic Resistance in Hospitalized Dogs: Impact of Prior Antibiotic Treatment
Authors: Aponrat Pojchanicha , Detkalaya Osathee , Phlongtong Naruemon , Eksatit Natnicha , Kananub Suppada , Kaewmongkol Sarawan , Kaewmongkol Gunn
Published: August 2024

Urethral catheterization, a common procedure in canine patients, often compromises urinary tract defenses, leading to bacterial colonization and potential systemic infection. Despite posi-tive urine cultures, clinical signs of urinary tract infection (UTI) may be absent in catheterized dogs. This study evaluated the correlation between urinalysis results and catheter-associated UTIs in hospitalized dogs, considering prior antibiotic treatment and antibiotic resistance. Twen-ty-eight dogs at Kasetsart University Veterinary Teaching Hospital were included. Urine cul-tures and antibiotic sensitivity tests were performed on days 0, 3, and 7 and prior to catheter re-moval, with a positive urine culture defined at ≥104 CFU/mL. Instances of pyuria (>5 WBCs/HPF), hematuria (>5 RBCs/HPF), and bacteriuria were recorded. A statistical analysis showed no significant association between the urine culture results and urinalysis parameters, catheterization duration, breed, sex, neutering status, or age. Dogs with prior antibiotic treat-ments exhibited UTI-free periods after catheter placement that were longer than those previous-ly reported. A Kaplan–Meier analysis showed a probability of being UTI-free of 92.8% at 3 days, declining to 60.7% by 7 days and 53.6% by 10 days. Alarmingly, eighty percent of the isolates (12/15) were multidrug-resistant organisms (MDROs), resistant to ≥3 antimicrobials. Routine urinalysis cannot reliably predict catheter-associated UTI, and the high rate of MDROs under-scores the need for judicious antibiotic use and improved diagnostic tools.
Prospects of Creating a Geopark in Ulytau Region of Kazakhstan: Geoheritage and Geotourism Potential
Authors: Nigmatova Saida , ZHOLTAEV Heroy , Pirogova Tatyana , Bekbotayeva Alma , Madiyarova Ilnura , Seidali Arman , Kalibek Balzhan , Kozhakhmet Bakhtyar
Published: August 2024

The Ulytau region located at the heart of Kazakhstan is one of the promising territories for setting up geopark. Here, in the centre of Kazakhstan is a geographical and economic region which consists of desert-steppe landscapes with small, steep low-mountain massifs. This is one of the largest regions of Kazakhstan in terms of industrial potential, wealth of minerals and raw materials, natural and cultural heritage. The world's largest copper-bearing province is located here. The geological history of this area tells of no less than 500 million years of planetary development. Despite the lengthy time that geology and the active use of resources were in focus, geoheritage objects were previously lacking attention and any characterization. In the Ulytau region, many preserved archaeological and ethnographic sites indicate that the Saryarka steppes were included in the trade and cultural sphere of the Great Silk Road. Geological, historical and sacred objects make this territory an extremely interesting object for the development of geotourism and the creation of geoparks as the basis for the sustainable development of the region.