bluuebunny/crossref_metadata_2025 huggingface dataset:
Perceptions and Attitudes of Correctional Staff Toward ADHD—A Challenging Disorder in Everyday Prison Life
Authors: Buadze Anna , Friedl Nadine , Schleifer Roman , Young Susan , Schneeberger Andres , Liebrenz Michael
Published: January 2021

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is associated with risk-taking behaviors, poor self-control, and interpersonal difficulties. Affected individuals have an increased probability of involvement with the criminal justice system, contributing to a higher rate of arrest, and imprisonment compared with the general population; they are also inadequately treated once sentenced. Because prison staff play a central role in the identification of inmates with mental disorders, they could well be key to improving provision of care. There is however little knowledge of the conceptions, perceptions, and attitudes of prison staff toward ADHD. Such information could help to identify starting points for awareness training and further implementation of specific ADHD treatment. To bridge this gap, we undertook a study based on a qualitatively-driven mixed methods design, combining qualitative data collection in the form of narrative interviews with 19 prison staff from a Swiss correctional facility with quantitative data collection in the form of a survey that included the Attitudes toward Prisoners scale. The interviews were analyzed with QSR NVIVO 11 and a qualitative content analysis approach was used to evaluate findings. Prison staff were generally aware of ADHD and its symptomology, believing it to a be “real,” but “fashionable” disorder and favoring hereditary-genetic or biological explanatory models for its development. They viewed inmates with ADHD rather negatively, as complicating correctional efforts, and perceived them as sticking out, as tying up more resources and as frequently being involved in confrontations. Our findings suggest that difficulties in pragmatic aspects of communication and language comprehension may be perceived “as not listening or following instructions,” creating additional tensions. Consequently, inmates with ADHD are more often exposed to disciplinary sanctions, such as solitary confinement—an intervention deemed “necessary” by staff. Therefore, staff training on ADHD might need to cover evidence on adverse effects. Non-pharmacological interventions for treatment were preferred and considered to be highly efficacious. Skepticism toward pharmacological treatment prevailed, even when benefits from stimulant medication were described. Interestingly, this skepticism was not the result of negative experiences with the misuse and diversion of stimulants. Acceptance of multimodal treatment among prison staff may require customized strategies.
Non-pharmacological Treatment for Elderly Individuals With Insomnia: A Systematic Review and Network Meta-Analysis
Authors: Kwon Chan-Young , Lee Boram , Cheong Moon Joo , Kim Tae-Hun , Jang Bo-Hyoung , Chung Sun Yong , Kim Jong Woo
Published: January 2021

Background: Insomnia causes a huge socioeconomic burden among the elderly, and is not simply a health problem. This study aimed to determine the comparative advantage of the effectiveness and acceptability of non-pharmacological interventions available for elderly individuals with insomnia.

Methods: Comprehensive searches in 13 medical databases were performed to find relevant randomized controlled trials (RCTs) up to August 2019. Two independent reviewers performed study selection, data extraction, and quality assessment of included RCTs using the Cochrane Collaboration's risk of bias. A network meta-analysis within the frequentist model was performed by combining direct and indirect evidence from all available RCTs. The primary outcomes were effectiveness as measured by the Pittsburgh Sleep Quality Index (PSQI) total score and acceptability by the incidence of all-cause drop-out.

Results: Twenty-eight RCTs involving 2,391 participants were included. Compared to wait-list, acupuncture (standardized mean difference −4.37, 95% confidence interval −8.53 to −0.12), acupuncture combined with benzodiazepines (−5.20, −9.82 to −0.57), behavioral therapy (−10.44, −17.31 to −3.58), benzodiazepines (−4.28, −8.45 to −0.11), benzodiazepines combined with cognitive behavioral therapy (CBT) (−7.18, −12.17 to −2.19), and CBT (−4.93, −8.63 to −1.22) showed significant superiority in their effectiveness. No significant comparative superiority or inferiority was found in terms of acceptability.

Conclusions: In terms of effectiveness as indicated by the PSQI total score, compared to wait-list, superior benefits were observed for acupuncture, acupuncture combined with benzodiazepines, behavioral treatment, benzodiazepines, benzodiazepines combined with CBT, and CBT. Importantly, combined treatments, including benzodiazepines combined with CBT or with acupuncture, were generally superior to other monotherapies. In terms of acceptability, there was not enough data to draw conclusions. However, most RCTs included had methodological problems related to the lack of blinding procedure, suggesting a risk of effect size overestimation.

Registration: CRD42019145518.
The Management of Psychiatric Emergencies in Situations of Public Calamity
Authors: Baldaçara Leonardo , da Silva Antônio Geraldo , Pereira Lucas Alves , Malloy-Diniz Leandro , Tung Teng Chei
Published: January 2021

The prevalence of mental health problems in the general population during a public calamity is high. In calamities, the number of patients who present with mental disorder outbreaks or crises may increase, but the necessary support systems to help them may be impaired if they have not been planned for. Although there are several models for addressing psychiatric emergencies, the general rules are the same, especially when it comes to making these services easily available to the affected population. In this article, we seek to review and present recommendations for the management of psychiatric emergencies in situations of public calamity, including disasters, physical and medical catastrophes, epidemics, and pandemics.
Immunotherapy in Autoantibody-Associated Psychiatric Syndromes in Adults
Authors: Hansen Niels , Timäus Charles
Published: January 2021

Background: Autoantibody-associated psychiatric syndromes are often distinct from, but might also be part of autoimmune encephalitis. Our article focuses on potential immunotherapy in these patients with a probable autoimmune origin of their psychiatric syndrome.

Methods: We searched through PubMed for appropriate articles on immunotherapy in autoantibody-associated psychiatric syndromes between 2010 and 2020 for this narrative review.

Results: In line with prior recommendations for autoimmune encephalitis and autoimmune psychosis, we suggest that in patients with a probable autoimmune-based psychiatric syndrome should be given early corticosteroids, intravenous immunoglobulins, or plasmapheresis as first line immunotherapy. If these therapeutic options fail, second-line immunotherapy should be applied within 1 month consisting of rituximab or cyclophosphamide. Maintenance therapy is best for those patients responding to steroids including mycofenolate mofetil or azathioprine. So far, there is evidence from a few retrospective cohort studies supporting the usage of first- and second-line, and maintenance immunotherapies for autoantibody-associated psychiatric syndromes. Some immunological agents are discussed that might exert an effect in autoimmune-based psychiatric syndromes, but the latest evidence is low and derived from case reports or series with autoimmune encephalitis patients.

Conclusions: Taken together, the immunotherapeutic landscape for patients with autoantibody-associated psychiatric syndromes is delineated. Our suggestions rely on observational studies in autoantibody-associated psychiatric syndromes and a few placebo-controlled, randomized trials for patients with autoimmune encephalitis and psychosis. Thus, adequate powered, prospective as well as placebo-controlled clinical trials in patients with autoantibody-associated psychiatric syndromes are warranted in order to enlighten efficacy and safety aspects of current and novel therapy strategies.
Sustainable Development Goal 11 and a New Urban Agenda for Caribbean Small Island Developing States: Policy, Practice, and Action
Authors: Mycoo Michelle A. , Bharath Keisha
Published: January 2021

Many Caribbean Small Island Developing States face the daunting task of fulfilling the United Nations Sustainable Development Goals by 2030. As signatories to the United Nations Sustainable Development Goals, their governments committed to embark on a roadmap to achieve sustainable development within this time frame. In this context, Caribbean Small Island Developing States have embraced Sustainable Development Goal 11 in pursuit of creating inclusive, safe, resilient, and sustainable cities as articulated in various governance, spatial, socio-economic, and environmental policies. Notwithstanding this commitment, a tension exists between policy and practice. Several barriers to policy implementation have stymied efforts to make progress in fulfilling Goal 11. Enabling the impact of sound policy through well-informed practice is pivotal, if these states are to make advancements in ensuring that their population has access to basic services and live in safe, resilient, and sustainable cities without leaving any citizen behind. This paper firstly seeks to critically review existing policies and practice that impact on the attainment of Sustainable Development Goal 11. It highlights the drivers of unsustainable urbanization that are undermining progress in achieving this key sustainable development goal. In keeping with the United Nations declaration of a Decade for Action, this paper secondly makes recommendations for action that are fundamental to putting Caribbean Small Island Developing States on a trajectory leading to the fulfillment of Goal 11. It specifically recommends strategic actions within the context of a New Urban Agenda that are relevant to Caribbean Small Island Developing States that are encountering similar challenges. The experience of Trinidad is drawn upon to provide a narrative of gaps between policy and practice, and to distill key actions for attaining SDG 11 by 2030 and beyond.
Comparisons of Macro-Kinematic Strategies During the Rounds of a Cross-Country Skiing Sprint Competition in Classic Technique
Authors: Marsland Finn , Anson Judith Mary , Waddington Gordon , Holmberg Hans-Christer , Chapman Dale Wilson
Published: January 2021

This study was designed to examine macro-kinematic parameters of six female cross-country skiers during the qualifying, semi-final and final rounds of a 1.1 km sprint competition in classical technique. During each round these skiers were monitored continuously with a single micro-sensor, and their cycle parameters and relative use of these two sub-techniques calculated. Within each round six sections of the course, during which all skiers employed either double pole (DP) or diagonal stride (DS) sub-technique, were chosen for additional analysis. The mean macro-kinematic cycle parameters and relative usage of sub-techniques over the full course did not differ significantly between rounds. On average 54% of the course was covered employing DP and 13% using DS, while 32% was covered utilizing a non-cyclical or irregular technique. With DP, the mean racing speed and cycle rate (CR) on the starting, middle and finishing sections of the course differed significantly, with no differences in mean cycle length (CL) between the last two sections. At the finish, higher DP speed was achieved by increasing CR. On the three hills, where all athletes utilized DS, mean racing speed and CL, but not mean CR, differed significantly. On these sections DS speed was increased by utilizing longer cycles. The individual skiers utilized a variety of macro-kinematic strategies during different rounds and on different sections of the course, depending on individual strengths, preferences and pacing strategies, as well as the course topography and tactical interactions with other skiers. Such collection of macro-kinematic data during competitions can help to identify an individual skier's strengths and weaknesses, guiding the testing of different cycle rates, and lengths on different terrains during training in order to optimize performance.
Physics-Based Digital Twin Identifies Trade-Offs Between Drying Time, Fruit Quality, and Energy Use for Solar Drying
Authors: Prawiranto Kevin , Carmeliet Jan , Defraeye Thijs
Published: January 2021

Solar drying is regarded as a less reliable process compared to continuous hot-air drying due to the intermittency of solar radiation. This problem is mitigated by equipping solar dryers with thermal storage, dehumidifier units, or auxiliary heating that enhances drying continuity during night time. In this study, we combine a mechanistic fruit drying model, quality models (vitamin C decay and browning reaction) and weather data to evaluate the drying characteristics and quality evolution of apple fruit with and without the aforementioned improvement strategies. By coupling to measured weather conditions, a digital twin of the drying fruit is established. The twin outputs drying times and final product quality for a specific fruit type and size, a particular dryer configuration, and specific weather conditions. The trade-offs between drying time, final product quality and energy use for the different improvement strategies of solar drying are documented. We found that solar drying may benefit from the slower drying due to the improvement of product quality. Compared to the other improvement strategies, dehumidification of the drying air is shown to be superior in retaining the vitamin C content and prohibiting the browning reaction. However, in general, drying with auxiliary heating is found to balance the trade-offs between drying time, final product quality and energy use since the weather-dependency of the process is mitigated. Additionally, we quantified the impact of a pre-treatment process that modifies the permeability of the fruit tissue by breaking the cell membrane. We found that inducing such lysis is more effective in decreasing the drying time when drying is conducted at low (room) temperature. This study shows that using the developed digital twin, future drying process and control strategies could be optimized in real-time for every single drying run.
Efficacy of Intercostal Nerve Block for Pain Control After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis
Authors: Chen Tao , Zhu ZhenQiang , Du Jianlong
Published: January 2021

Background:We aimed to assess the efficacy of intercostal nerve block (ICNB) for pain relief after percutaneous nephrolithotomy (PCNL).

Methods:An electronic search of the databases of PubMed, Science Direct, BioMed Central, CENTRAL, Embase, and Google Scholar was conducted. All types of studies conducted on adult patients undergoing PCNL, comparing ICNB with control or any other anesthetic method, and reporting postoperative pain outcomes were included.

Results:Six studies were included. Studies compared ICNB with peritubal (PT) infiltration and with control. Pooled analysis of ICNB vs. PT infiltration indicated no difference between the two groups for pain scores at 6–8 h (MD −0.44; 95% CI −3.41, 2.53; I2= 99%;p= 0.77), 12 h (MD −0.98; 95% CI −4.90, 2.94; I2= 99%;p= 0.62) and 24 h (MD 0.16; 95% CI −0.90, 1.21; I2= 88%;p= 0.77). Time for first analgesic demand was also not significantly different between the two groups. Meta-analysis of ICNB vs. control indicated statistical significant difference in pain scores between the two groups at 8 h (MD −1.55; 95% CI −2.60, −0.50; I2= 47%;p= 0.04), 12 h (SMD −2.49; 95% CI −4.84, −0.13; I2= 96%;p= 0.04) and 24 h (SMD −1.22; 95% CI −2.12, −0.32; I2= 88%;p= 0.008). The total analgesic requirement in morphine equivalents was not significantly different between the two groups.

Conclusions:ICNB may be effective in reducing postoperative pain after PCNL. However, its efficacy may not be greater than PT infiltration. Current evidence is from a limited number of studies. Further, high-quality randomized controlled trials are needed to provide robust evidence.
Acknowledgment to Reviewers of Acoustics in 2020
Authors:   Acoustics Editorial Office
Published: January 2021

Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Acoustics maintains its standards for the high quality of its published papers [...]
Concentrations of Inorganic and Organic Pollutants in Forest Soils as an Archive of Anthropogenic Inputs in the State of Brandenburg, Germany
Authors: Riek Winfried , Russ Alexander , Marx Marc
Published: January 2021

An important component of the National Forest Soils Inventory (NFSI) is the investigation of inorganic and organic pollutants. Forests are able to filter out large quantities of these substances from the atmosphere and incorporate them into the soil for a long time. The aim of this study was the integrative evaluation of organic and inorganic pollutant concentrations in forest soils in the state of Brandenburg, Germany. With the help of principle component analysis, the pollutant concentrations can essentially be explained by three significant environmental components, which explain 76% of the total variance of all pollutants examined within the scope of the NFSI. The first component characterizes the extent of the atmospheric pollution caused by flue gases and fly ash from lignite combustion in the 1970s and 1980s and is mainly charged by the organic pollutants HCB and PAH, and the elements arsenic and chromium. This component shows positive relation to both spatially interpolated calcium-deposition data from the 1980s (as an indicator for the dust emission from coal combustion) and crown defoliation data of pine stands from the forest condition survey in the early 1990s. The depositions of zinc and cadmium from industrial sources, vehicle traffic and the use of fertilizers in agriculture mainly characterize the second principle component. The use of the pesticides DDT and lindane in the early 1980s and the associated pollutants input into the forest soils are expressed by the third component. In expanding the term archiving function of soils, the results illustrate their particular importance for the long-term archiving of anthropogenic inputs and the associated potential stress factors for forests.
Effect of Wet Deposition on Secondary Inorganic Aerosols Using an Urban-Scale Air Quality Model
Authors: Kim Kwandong D. , Lee Seungyeon , Kim Jae-Jin , Lee Sang-Hyun , Lee DaeGyun , Lee Jae-Bum , Choi Jin-Young , Kim Minjoong J.
Published: January 2021

We investigated the effects of wet deposition on secondary inorganic aerosols (SIAs) in urban areas by coupling the wet deposition module with the three-dimensional computational fluid dynamics atmospheric chemistry model (CFD-Chem). We developed a wet deposition model for the microscale model by improving on the global modeling initiative scheme. We evaluated the model by comparing it to the observed washout ratio from the total wet deposition. The simulated washout ratio calculated using the wet scavenging coefficient (WSC) based on the theoretical calculation is six times lower than that observed, suggesting that the wet deposition amount of SIAs from below-cloud scavenging might be underestimated. When we applied the WSC based on field measurements, the washout ratio was much improved; however, it was slightly overestimated compared to the observed rate. Therefore, we estimated the optimal WSC for SIAs in the urban area using a linear regression approach. We conducted a model using the wet deposition of SIAs in a megacity to understand the effects of wet deposition on the SIA concentration using estimated optimal WSCs. The simulated results indicate that washout processes decrease the surface aerosol concentration, showing that reductions in the average surface concentrations from washout processes were from 7.1% to 11.2%. The simulation results suggest that washout processes can reduce the particulate matter concentration in urban areas, indicating that washout processes should be considered in the microscale model, although the modeling domain can only simulate washout processes.
Neural Network-Based Models for Estimating Weighted Mean Temperature in China and Adjacent Areas
Authors: Long Fengyang , Hu Wusheng , Dong Yanfeng , Wang Jinling
Published: January 2021

The weighted mean temperature (Tm) is a key parameter when converting the zenith wet delay (ZWD) to precipitation water vapor (PWV) in ground-based Global Navigation Satellite System (GNSS) meteorology. Tm can be calculated via numerical integration with the atmospheric profile data measured along the zenith direction, but this method is not practical in most cases because it is not easy for general users to get real-time atmospheric profile data. An alternative method to obtain an accurate Tm value is to establish regional or global models on the basis of its relations with surface meteorological elements as well as the spatiotemporal variation characteristics of Tm. In this study, the complex relations between Tm and some of its essentially associated factors including the geographic position and terrain, surface temperature and surface water vapor pressure were considered to develop Tm models, and then a non-meteorological-factor Tm model (NMFTm), a single-meteorological-factor Tm model (SMFTm) and a multi-meteorological-factor Tm model (MMFTm) applicable to China and adjacent areas were established by adopting the artificial neural network technique. The generalization performance of new models was strengthened with the help of an ensemble learning method, and the model accuracies were compared with several representative published Tm models from different perspectives. The results show that the new models all exhibit consistently better performance than the competing models under the same application conditions tested by the data within the study area. The NMFTm model is superior to the latest non-meteorological model and has the advantages of simplicity and utility. Both the SMFTm model and MMFTm model show higher accuracy than all the published Tm models listed in this study; in particular, the MMFTm model is about 14.5% superior to the first-generation neural network-based Tm (NN-I) model, with the best accuracy so far in terms of the root-mean-square error.
Variations in Levels and Sources of Atmospheric VOCs during the Continuous Haze and Non-Haze Episodes in the Urban Area of Beijing: A Case Study in Spring of 2019
Authors: Zhang Lihui , Wang Xuezhong , Li Hong , Cheng Nianliang , Zhang Yujie , Zhang Kai , Li Lei
Published: January 2021

To better evaluate the variations in concentration characteristics and source contributions of atmospheric volatile organic compounds (VOCs) during continuous haze days and non-haze days, hourly observations of atmospheric VOCs were conducted using a continuous on-line GC-FID (Airmo VOC GC-866) monitoring system during 1–15 March 2019, in urban areas of Beijing, China. The results showed that the total VOC concentrations during haze days and non-haze days were 59.13 ± 31.08 μg/m3 and 16.91 ± 7.19 μg/m3, respectively. However, the average O3 concentrations during the two haze days were lower than those of non-haze days due to the extremely low concentrations at night instead of the reported lower photochemical reaction in daytime. The ratio of OH radical concentration during haze and non-haze days indicating that the rate of photochemical reaction during haze days was higher than those of non-haze days from 13:00–19:00. The stable air conditions and the local diesel emission at night were the main reasons for the decreased O3 concentrations during haze days. Six major sources were identified by positive matrix factorization (PMF), namely, diesel exhaust, combustion, gasoline evaporation, solvent usage, gasoline exhaust, and the petrochemical industry, contributing 9.93%, 25.29%, 3.90%, 16.88%, 35.59% and 8.41%, respectively, during the whole observation period. The contributions of diesel exhaust and the petrochemical industry emissions decreased from 26.14% and 6.43% during non-haze days to 13.70% and 2.57%, respectively, during haze days. These reductions were mainly ascribed to the emergency measures that the government implemented during haze days. In contrast, the contributions of gasoline exhaust increased from 34.92% during non-haze days to 48.77% during haze days. The ratio of specific VOC species and PMF both showed that the contributions of gasoline exhaust emission increased during haze days. The backward trajectories, potential source contribution function (PSCF) and concentration weighted trajectory (CWT) showed that the air mass of VOCs during haze days was mainly affected by the short-distance transportation from the southwestern of Hebei province. However, the air mass of VOCs during non-haze days was mainly affected by the long-distance transportation from the northwest.
An Exploratory Study of COVID-19 Information on Twitter in the Greater Region
Authors: Chen Ninghan , Zhong Zhiqiang , Pang Jun
Published: January 2021

The outbreak of the COVID-19 led to a burst of information in major online social networks (OSNs). Facing this constantly changing situation, OSNs have become an essential platform for people expressing opinions and seeking up-to-the-minute information. Thus, discussions on OSNs may become a reflection of reality. This paper aims to figure out how Twitter users in the Greater Region (GR) and related countries react differently over time through conducting a data-driven exploratory study of COVID-19 information using machine learning and representation learning methods. We find that tweet volume and COVID-19 cases in GR and related countries are correlated, but this correlation only exists in a particular period of the pandemic. Moreover, we plot the changing of topics in each country and region from 22 January 2020 to 5 June 2020, figuring out the main differences between GR and related countries.
Theranostic Design of Angiopep-2 Conjugated Hyaluronic Acid Nanoparticles (Thera-ANG-cHANPs) for Dual Targeting and Boosted Imaging of Glioma Cells
Authors: Costagliola di Polidoro Angela , Zambito Giorgia , Haeck Joost , Mezzanotte Laura , Lamfers Martine , Netti Paolo Antonio , Torino Enza
Published: January 2021

Glioblastoma multiforme (GBM) has a mean survival of only 15 months. Tumour heterogeneity and blood-brain barrier (BBB) mainly hinder the transport of active agents, leading to late diagnosis, ineffective therapy and inaccurate follow-up. The use of hydrogel nanoparticles, particularly hyaluronic acid as naturally occurring polymer of the extracellular matrix (ECM), has great potential in improving the transport of drug molecules and, furthermore, in facilitatating the early diagnosis by the effect of hydrodenticity enabling the T1 boosting of Gadolinium chelates for MRI. Here, crosslinked hyaluronic acid nanoparticles encapsulating gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) and the chemotherapeutic agent irinotecan (Thera-cHANPs) are proposed as theranostic nanovectors, with improved MRI capacities. Irinotecan was selected since currently repurposed as an alternative compound to the poorly effective temozolomide (TMZ), generally approved as the gold standard in GBM clinical care. Also, active crossing and targeting are achieved by theranostic cHANPs decorated with angiopep-2 (Thera-ANG-cHANPs), a dual-targeting peptide interacting with low density lipoprotein receptor related protein-1(LRP-1) receptors overexpressed by both endothelial cells of the BBB and glioma cells. Results showed preserving the hydrodenticity effect in the advanced formulation and internalization by the active peptide-mediated uptake of Thera-cHANPs in U87 and GS-102 cells. Moreover, Thera-ANG-cHANPs proved to reduce ironotecan time response, showing a significant cytotoxic effect in 24 h instead of 48 h.
Sustainable Hydrogenation of Vinyl Derivatives Using Pd/C Catalysts
Authors: Mironenko Roman M. , Saybulina Elina R. , Stepanova Liudmila N. , Gulyaeva Tatiana I. , Trenikhin Mikhail V. , Rodygin Konstantin S. , Ananikov Valentine P.
Published: January 2021

The hydrogenation of unsaturated double bonds with molecular hydrogen is an efficient atom-economic approach to the production of a wide range of fine chemicals. In contrast to a number of reducing reagents typically involved in organic synthesis, hydrogenation with H2 is much more sustainable since it does not produce wastes (i.e., reducing reagent residues). However, its full sustainable potential may be achieved only in the case of easily separable catalysts and high reaction selectivity. In this work, various Pd/C catalysts were used for the liquid-phase hydrogenation of O-, S-, and N-vinyl derivatives with molecular hydrogen under mild reaction conditions (room temperature, pressure of 1 MPa). Complete conversion and high hydrogenation selectivity (>99%) were achieved by adjusting the type of Pd/C catalyst. Thus, the proposed procedure can be used as a sustainable method for vinyl group transformation by hydrogenation reactions. The discovery of the stability of active vinyl functional groups conjugated with heteroatoms (O, S, and N) under hydrogenation conditions over Pd/C catalysts opens the way for many useful transformations.
Projected Changes in Water Year Types and Hydrological Drought in California’s Central Valley in the 21st Century
Authors: He Minxue , Anderson Jamie , Lynn Elissa , Arnold Wyatt
Published: January 2021

The study explores the potential changes in water year types and hydrological droughts as well as runoff, based on which the former two metrics are calculated in the Central Valley of California, United States, in the 21st century. The latest operative projections from four representative climate models under two greenhouse-gas emission scenarios are employed for this purpose. The study shows that the temporal distribution of annual runoff is expected to change in terms of shifting more volume to the wet season (October–March) from the snowmelt season (April–July). Increases in wet season runoff volume are more noticeable under the higher (versus lower) emission scenario, while decreases in snowmelt season runoff are generally more significant under the lower (versus higher) emission scenario. In comparison, changes in the water year types are more influenced by climate models rather than emission scenarios. When comparing two regions in the Central Valley, the rain-dominated Sacramento River region is projected to experience more wet years and less critical years than the snow-dominated San Joaquin River region due to their hydroclimatic and geographic differences. Hydrological droughts in the snowmelt season and wet season mostly exhibit upward and downward trends, respectively. However, the uncertainty in the direction of the trend on annual and multi-year scales tends to be climate-model dependent. Overall, this study highlights non-stationarity and long-term uncertainty in these study metrics. They need to be considered when developing adaptive water resources management strategies, some of which are discussed in the study.
Prevalence of Insomnia in Two Saskatchewan First Nation Communities
Authors: Dosman James A , Karunanayake Chandima P , Fenton Mark , Ramsden Vivian R , Skomro Robert , Kirychuk Shelley , Rennie Donna C , Seeseequasis Jeremy , Bird Clifford , McMullin Kathleen , Russell Brooke P , Koehncke Niels , Smith-Windsor Thomas , King Malcolm , Abonyi Sylvia , Pahwa Punam
Published: January 2021

Insomnia is a common problem in Canada and has been associated with increased use of health care services and economic burden. This paper examines the prevalence and risk factors for insomnia in two Cree First Nation communities in Saskatchewan, Canada. Five hundred and eighty-eight adults participated in a baseline survey conducted as part of the First Nations Sleep Health Collaborative Project. The prevalence of insomnia was 19.2% among participants with an Insomnia Severity Index score of ≥15. Following the definition of nighttime insomnia symptoms, however, the prevalence of insomnia was much higher, at 32.6%. Multivariate logistic regression modeling revealed that age, physical health, depression diagnosis, chronic pain, prescription medication use for any health condition, and waking up during the night due to terrifying dreams, nightmares, or flashbacks related to traumatic events were risk factors for insomnia among participants from two Saskatchewan Cree First Nation communities.
Acknowledgment to Reviewers of Epigenomes in 2020
Authors:   Epigenomes Editorial Office
Published: January 2021

Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Epigenomes maintains its standards for the high quality of its published papers [...]
Assessing Sustainable Bamboo-Based Income Generation Using a Value Chain Approach: Case Study of Nongboua Village in Lao PDR
Authors: Lee Bohwi , Rhee Hakjun , Kim Sebin , Lee Joon-Woo , Koo Seungmo , Lee Sang-Jin , Alounsavath Phayvanh , Kim Yeon-Su
Published: January 2021

Many bamboo species are well suited for agroforestry as they are more versatile and rapidly renewable than trees. Bamboo is an important income source for rural villagers around the world, especially in tropical developing countries, such as Lao PDR (Lao People’s Democratic Republic). This study applied a value chain approach to compare potential incomes from different bamboo utilization models: (1) existing model of selling semi-processed raw materials (bamboo splits), and (2) new model of producing handcraft products locally. Using a rural village in eastern Lao PDR (Nongboua village in Vientiane Capital province) as a case study, we provided empirical assessments of two bamboo value chains. Based on interviews with the villagers and stakeholders and government statistical data from 2017 to 2019, existing and new bamboo production chains were evaluated. In the existing value chain, the final products, bamboo chopsticks, are worth $6.74/kg. The value chain starts with bamboo harvesting, collection, and management, which are done by villagers in Lao PDR and taxed by the Lao PDR government. Bamboo splits are then transported to Vietnam to make the final products to sell. Local villagers received only 4.9% of the total value. The new bamboo handicraft model could produce 9 bamboo cups and 60 medals from one bamboo stem worth $52.6–61.7 and $343.8. In this value chain, bamboo harvesting, management, and processing to final products are done by villagers. The handcrafts were collected by traders to be sold at souvenir shops. Local villagers could capture 29.4%–42.3% of the total values. Producing bamboo cup and medal could generate 1.12–2.17 and 234.8–244.6 times higher income for villagers per labor hour and per bamboo stem, respectively, and allow them to use more bamboo resource than producing bamboo splits to export to Vietnam. If applied to other rural areas in Lao PDR, the new bamboo product model for handicrafts can be a better income source for local villagers in Lao PDR with sustainable use of bamboo resources than the existing model. However, it requires extensive bamboo handicrafts training over a year. Although alternative uses of bamboo would be different depending on social, economic, and market contexts, the value chain analysis demonstrated in this study can be applied elsewhere to increase local retention of economic values generated from agroforestry.
Acknowledgment to Reviewers of Fractal and Fractional in 2020
Authors:   Fractal and Fractional Editorial Office
Published: January 2021

Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Fractal and Fractional maintains its standards for the high quality of its published papers [...]
Long-Term Waterlogging as Factor Contributing to Hypoxia Stress Tolerance Enhancement in Cucumber: Comparative Transcriptome Analysis of Waterlogging Sensitive and Tolerant Accessions
Authors: Kęska Kinga , Szcześniak Michał Wojciech , Makałowska Izabela , Czernicka Małgorzata
Published: January 2021

Waterlogging (WL), excess water in the soil, is a phenomenon often occurring during plant cultivation causing low oxygen levels (hypoxia) in the soil. The aim of this study was to identify candidate genes involved in long-term waterlogging tolerance in cucumber using RNA sequencing. Here, we also determined how waterlogging pre-treatment (priming) influenced long-term memory in WL tolerant (WL-T) and WL sensitive (WL-S) i.e., DH2 and DH4 accessions, respectively. This work uncovered various differentially expressed genes (DEGs) activated in the long-term recovery in both accessions. De novo assembly generated 36,712 transcripts with an average length of 2236 bp. The results revealed that long-term waterlogging had divergent impacts on gene expression in WL-T DH2 and WL-S DH4 cucumber accessions: after 7 days of waterlogging, more DEGs in comparison to control conditions were identified in WL-S DH4 (8927) than in WL-T DH2 (5957). Additionally, 11,619 and 5007 DEGs were identified after a second waterlogging treatment in the WL-S and WL-T accessions, respectively. We identified genes associated with WL in cucumber that were especially related to enhanced glycolysis, adventitious roots development, and amino acid metabolism. qRT-PCR assay for hypoxia marker genes i.e., alcohol dehydrogenase (adh), 1-aminocyclopropane-1-carboxylate oxidase (aco) and long chain acyl-CoA synthetase 6 (lacs6) confirmed differences in response to waterlogging stress between sensitive and tolerant cucumbers and effectiveness of priming to enhance stress tolerance.
PUFA Treatment Affects C2C12 Myocyte Differentiation, Myogenesis Related Genes and Energy Metabolism
Authors: Risha Marua Abu , Siengdee Puntita , Dannenberger Dirk , Wimmers Klaus , Ponsuksili Siriluck
Published: January 2021

Polyunsaturated fatty acids (PUFAs) are the main components of cell membrane affecting its fluidity, signaling processes and play a vital role in muscle cell development. The effects of docosahexaenoic acid (DHA) on myogenesis are well known, while the effects of arachidonic acid (AA) are largely unclear. The purpose of this study is to evaluate the effect of two PUFAs (DHA and AA) on cell fate during myogenic processes, Wnt signaling and energy metabolism by using the C2C12 cells. The cells were treated with different concentrations of AA or DHA for 48 h during the differentiation period. PUFA treatment increased mRNA level of myogenic factor 5 (Myf5), which is involved in early stage of myoblast proliferation. Additionally, PUFA treatment prevented myoblast differentiation, indicated by decreased myotube fusion index and differentiation index in parallel with reduced mRNA levels of myogenin (MyoG). After PUFA withdrawal, some changes in cell morphology and myosin heavy chain mRNA levels were still observed. Expression of genes associated with Wnt signaling pathway, and energy metabolism changed in PUFA treatment in a dose and time dependent manner. Our data suggests that PUFAs affect the transition of C2C12 cells from proliferation to differentiation phase by prolonging proliferation and preventing differentiation.
Monitoring the Spatial Variation of Aerosol Optical Depth and Its Correlation with Land Use/Land Cover in Wuhan, China: A Perspective of Urban Planning
Authors: Xie Qijiao , Sun Qi
Published: January 2021

Aerosols significantly affect environmental conditions, air quality, and public health locally, regionally, and globally. Examining the impact of land use/land cover (LULC) on aerosol optical depth (AOD) helps to understand how human activities influence air quality and develop suitable solutions. The Landsat 8 image and Moderate Resolution Imaging Spectroradiometer (MODIS) aerosol products in summer in 2018 were used in LULC classification and AOD retrieval in this study. Spatial statistics and correlation analysis about the relationship between LULC and AOD were performed to examine the impact of LULC on AOD in summer in Wuhan, China. Results indicate that the AOD distribution expressed an obvious “basin effect” in urban development areas: higher AOD values concentrated in water bodies with lower terrain, which were surrounded by the high buildings or mountains with lower AOD values. The AOD values were negatively correlated with the vegetated areas while positively correlated to water bodies and construction lands. The impact of LULC on AOD varied with different contexts in all cases, showing a “context effect”. The regression correlations among the normalized difference vegetation index (NDVI), normalized difference built-up index (NDBI), normalized difference water index (NDWI), and AOD in given landscape contexts were much stronger than those throughout the whole study area. These findings provide sound evidence for urban planning, land use management and air quality improvement.
Reliability of a Risk-Factor Questionnaire for Osteoporosis: A Primary Care Survey Study with Dual Energy X-ray Absorptiometry Ground Truth
Authors: Radeva Maria , Predel Dorothee , Winzler Sven , Teichgräber Ulf , Pfeil Alexander , Malich Ansgar , Papageorgiou Ismini
Published: January 2021

(1) Purpose: Predisposing factors to osteoporosis (OP) as well as dual-source x-ray densitometry (DXA) steer therapeutic decisions by determining the FRAX index. This study examines the reliability of a standard risk factor questionnaire in OP-screening. (2) Methods: n = 553 eligible questionnaires encompassed 24 OP-predisposing factors. Reliability was assessed using DXA as a gold standard. Multiple logistic regression and Spearman’s correlations, as well as the confounding influence of age and body mass index, were analyzed in SPSS (IBM Corporation, Armonk, NY, USA). (3) Results: Our study revealed low patient self-awareness regarding OP and its risk factors. One out of every four patients reported a positive history for osteoporosis not confirmed by DXA. The extraordinarily high incidence of rheumatoid arthritis and thyroid disorders likely reflect confusion with other diseases or health anxiety. FRAX-determining risk factors such as malnutrition, liver insufficiency, prior fracture without trauma, and glucocorticoid therapy did not correlate with increased OP incidence, altogether demonstrating how inaccurate survey information could influence therapeutic decisions on osteoporosis. (4) Conclusions: Contradictive results and a low level of patient self-awareness suggest a high degree of uncertainty and low reliability of the current OP risk factor survey.
Accelerometry-Workload Indices Concerning Different Levels of Participation during Congested Fixture Periods in Professional Soccer: A Pilot Study Conducted over a Full Season
Authors: Clemente Filipe Manuel , Silva Rui , Chen Yung-Sheng , Aquino Rodrigo , Praça Gibson Moreira , Castellano Julen , Nobari Hadi , Mendes Bruno , Rosemann Thomas , Knechtle Beat
Published: January 2021

The aim of this study was to analyze the variations of acute load (AL), acute: chronic workload ratio (ACWR), training monotony (TM), and training strain (TS) of accelerometry-based GPS measures in players who started in three matches (S3M), two matches (S2M), and one match (S1M) during congested weeks. Nineteen elite professional male players from a Portuguese team (age: 26.5 ± 4.3 years) were monitored daily using global positioning systems (GPSs) over a full season (45 weeks). Accelerometry-derived measures of high metabolic load distance (HMLD), high accelerations (HA), and high decelerations (HD) were collected during each training session and match. Seven congested weeks were classified throughout the season, and the participation of each player in matches played during these weeks was codified. The workload indices of AL (classified as ACWR, TM, and TS) were calculated weekly for each player. The AL of HMLD was significantly greater for S2M than S1M (difference = 42%; p = 0.002; d = 0.977) and for S3M than S1M (difference = 44%; p = 0.001; d = 1.231). Similarly, the AL of HA was significantly greater for S2M than S1M (difference = 25%; p = 0.023; d = 0.735). The TM of HD was significantly greater for S2M than S3M (difference = 25%; p = 0.002; d = 0.774). Accelerometry-based measures were dependent on congested fixtures. S2M had the greatest TS values, while S3M had the greatest TM.
Measuring Food Literacy: Progressing the Development of an International Food Literacy Survey Using a Content Validity Study
Authors: Fingland Donna , Thompson Courtney , Vidgen Helen Anna
Published: January 2021

Background: The term “food literacy” is increasingly used to describe the knowledge, skills and behaviours needed to meet food needs. The aim of this research was to determine content validity for an International Food Literacy Survey. Methods: The literature was searched for existing items to form an item pool to measure the eleven components of food literacy. Expert consensus was investigated through two related online surveys. Round 1 participants were researchers who had been involved in the development of a food literacy measure (n = 18). Round 2 participants were authors of papers who had used the term (n = 85). Level of agreement was determined quantitatively using the Content Validity Index and compared to open ended qualitative comments. Results: Consensus was achieved on 119 items. Components varied in the ease with which existing validated items could be found and the number of items achieving consensus. Items related to food prepared within the home were more likely to achieve consensus. Additional issues included limited shared understanding of the scope of the term, the validity of items varying according to context and a limited health focus. Conclusions: This study provides a valuable basis upon which to progress the development of a measure.
Research on the Evolution of the Express Packaging Recycling Strategy, Considering Government Subsidies and Synergy Benefits
Authors: Guo Yanlu , Luo Gongli , Hou Guisheng
Published: January 2021

With the year-on-year growth of e-commerce transactions and the increasing popularity of the concept of ecological civilization, the waste and recycling of express packages have aroused widespread discussion and attention. On the issue of express package recycling, how consumers, e-commerce enterprises, and e-commerce platforms choose their own strategies, how to better promote the recycling of express packages, and what is the effect mechanism of government subsidies on different players. These are the questions that this article wants to answer. Since this article involves many stakeholders, in order to better identify the strategic choice and evolution of different entities and to better study the influence of government subsidies on the strategic choice of game players, this article uses two triparty evolutionary game models. The results show that without subsidies, changes in the rate of return and the initial probability will affect the evolution of the equilibrium strategy, while the synergistic benefits will have a corrective effect in some cases; when government subsidies are included and the probability of the three parties choosing “green strategies” is relatively low, subsidies should be paid to e-commerce companies mainly; lower subsidies can only provide incentives for e-commerce platforms. This article can provide certain references and value for government policymakers.