bluuebunny/crossref_metadata_2025 huggingface dataset:
Microbial Response to Coastal-Offshore Gradients in Taiwan Straits: Community Metabolism and Total Prokaryotic Abundance as Potential Proxies
Authors: Wan Lingling , Caruso Gabriella , Cao Xiuyun , Song Chunlei , Maimone Giovanna , Rappazzo Alessandro Ciro , Laganà Pasqualina , Zhou Yiyong
Published: May 2022

Located between the South and the East China Sea, the Taiwan Straits (TWS) are a marine shelf-channel area, with unique hydrological and geomorphological features affected by rivers inflow and with recent algal blooms with red tide events. This study aimed at assessing microbial distribution and function and their modulation in response to environmental gradients. Surface (0.5 m) water samples from 16 stations along five north to south transects were collected; total prokaryotic abundance by epifluorescence microscope and carbon substrate utilization patterns by Biolog Ecoplates were estimated. Spatially, a patchy microbial distribution was found, with the highest microbial metabolic levels and prokaryotic abundance in the TWS area between Minjiang River estuary and Pingtan Island, and progressive decreases towards offshore stations. Complex carbon sources and carbohydrates were preferentially metabolized. This study provides a snapshot of the microbial abundance and activity in TWS as a model site of aquatic ecosystems impacted from land inputs; obtained data highlights that microbial metabolism is more sensitive than abundance to environmental changes.
Tibial plateau fractures: three dimensional fracture mapping and morphologic measurements
Authors: Yao Peifeng , Gong Maoqi , Shan Lei , Wang Dong , He Yuanming , Wang Hanzhou , Zhou Junlin
Published: May 2022

Purpose

The injury mechanisms and classifications of tibial plateau fractures (TPFs) are still controversial. The aim of this study is to show 3D fracture mapping of different types of tibial plateau fractures. Moreover, combined with Schatzker and ten-segment classification, we aimed to analyze the injury frequency and characteristics of different segments.

Methods

In total, 346 patients with TPFs treated at level I trauma centres from 2017 to 2021 were reviewed. The CT files of the included cases were typed and categorized. 3D reconstruction of TPFs patients’ CT files were performed using software. All fracture lines were superimposed on the standard model by the software to create TPFs 3D fracture mapping.

Results

This study included 204 male and 142 female patients (average age, 47 years [range, 18 to 83 years]) with a tibial plateau fracture. Using the Schatzker classification, we found 39 type I (11.27%), 103 type II (29.77%), nine type III (2.60%), 71 type IV (20.52%), 52 type V (15.03%), 59 type VI (17.05%) fractures, and 13 others (3.76%). The density areas of fracture lines are mainly located in the ALC and PLC segments (74.3%, 69.1%). In different views, fracture lines of different Schatzker types showed distinct distribution characteristics.

Conclusions

Schatzker classification combined with 3D fracture mapping provides a new presentation of tibial plateau fracture morphology. According to the 3D fracture mapping, different types of TPFs have distinctly different distribution characteristics of fracture lines. There are significant differences between different types of fracture injury segments.
Reliability of estimating left ventricular ejection fraction in clinical routine: a validation study of the SWEDEHEART registry
Authors: Lenell Joel , Lindahl Bertil , Karlsson Per , Batra Gorav , Erlinge David , Jernberg Tomas , Spaak Jonas , Baron Tomasz
Published: May 2022

Objective

Patients hospitalized with acute coronary syndrome (ACS) in Sweden routinely undergo an echocardiographic examination with assessment of left ventricular ejection fraction (LVEF). LVEF is a measurement widely used for outcome prediction and treatment guidance. The obtained LVEF is categorized as normal (> 50%) or mildly, moderately, or severely impaired (40–49, 30–39, and < 30%, respectively) and reported to the nationwide registry for ACS (SWEDEHEART). The purpose of this study was to determine the reliability of the reported LVEF values by validating them against an independent re-evaluation of LVEF.

Methods

A random sample of 130 patients from three hospitals were included. LVEF re-evaluation was performed by two independent reviewers using the modified biplane Simpson method and their mean LVEF was compared to the LVEF reported to SWEDEHEART. Agreement between reported and re-evaluated LVEF was assessed using Gwet’s AC2 statistics.

Results

Analysis showed good agreement between reported and re-evaluated LVEF (AC2: 0.76 [95% CI 0.69–0.84]). The LVEF re-evaluations were in agreement with the registry reported LVEF categorization in 86 (66.0%) of the cases. In 33 (25.4%) of the cases the SWEDEHEART-reported LVEF was lower than re-evaluated LVEF. The opposite relation was found in 11 (8.5%) of the cases (p < 0.005).

Conclusion

Independent validation of SWEDEHEART-reported LVEF shows an overall good agreement with the re-evaluated LVEF. However, a tendency towards underestimation of LVEF was observed, with the largest discrepancy between re-evaluated LVEF and registry LVEF in subjects with subnormal LV-function in whom the reported assessment of LVEF should be interpreted more cautiously.

Graphical abstract
Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation
Authors: Lenz Maximilian , Kahmann Stephanie , Behbahani Mehdi , Pennig Lenhard , Hackl Michael , Leschinger Tim , Müller Lars Peter , Wegmann Kilian
Published: May 2022

Introduction

In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration.

Materials and methods

Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer’s classification was used to analyse the fractures.

Results

In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities.

Conclusion

A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education.

Level of Evidence

III.
Exhumation of a migmatitic unit through self-enhanced magmatic weakening enabled by tectonic contact metamorphism (Gruf complex, Central European Alps)
Authors: Mintrone M. , Galli A. , Schmidt M. W.
Published: May 2022

The Central Alpine lower crustal migmatitic Gruf complex was exhumed in contact to the greenschist-grade Chiavenna ophiolite and gneissic Tambo nappe leading to a lateral gradient of ~ 70 °C/km within the ophiolite. The 14 km long, E-W striking subvertical contact now bridges metamorphic conditions of ~ 730 °C, 6.6 kbar in the migmatitic gneisses and ~ 500 °C, 4.2 kbar in the serpentinites and Tambo schists 2–4 km north of the contact. An obvious fault, mylonite or highly sheared rock that could accommodate the ~ 8.5 km vertical displacement is not present. Instead, more than half of the movement was accommodated in a 0.2–1.2 km thick orthogneiss of the Gruf complex that was heterogeneously molten. Discrete bands with high melt fractions (45–65%) now contain variably stretched enclaves of the adjacent MOR-derived amphibolite. In turn, the adjacent amphibolites exhibit tonalitic in-situ leucosomes and dikes i.e., were partially molten. The H2O necessary for fluid-assisted melting of the orthogneiss and amphibolites was likely derived from the tectonic contact metamorphism of the Chiavenna serpentinites, at the contact now in enstatite + olivine-grade. U–Pb dating of zircons shows that partial melting and diking occurred at 29.0–31.5 Ma, concomitant with the calc-alkaline Bergell batholith that intruded the Gruf. The major driving forces of exhumation were hence the strong regional North–South shortening in the Alpine collisional belt and the buoyancy provided by the Bergell magma. The fluids available through tectonic contact metamorphism led to self-enhanced magmatic weakening and concentration of movement in an orthogneiss, where melt-rich bands provided a low friction environment. Continuous heating of the originally greenschist Chiavenna ophiolite and Tambo gneisses + schists by the migmatitic Gruf complex during differential uplift explains the skewed temperature profile, with intensive contact heating in the ophiolite but little cooling in the portion of the now-exposed Gruf complex.
Introduction of Small Stitch Small Bite technique: a retrospective long-term follow-up
Authors: Söderbäck Harald , Masood Arslan , Leo Jonas , Sandblom Gabriel
Published: May 2022

Purpose

Standardization of abdominal wall closure is suggested to improve quality and reduce the risk for late abdominal wall complications. The purpose of this study was to explore the impact of a structured introduction of guidelines for abdominal wall closure on the rates of incisional hernia and wound dehiscence.

Methods

All procedures performed via a midline incision in 2010–2011 and 2016–2017 at Capio St Göran’s Hospital were identified and assessed for complications and risk factors.

Results

Six hundred two procedures were registered in 2010–2011, and 518 in 2016–2017. Four years after the implementation of new guidelines, 93% of procedures were performed using the standardized technique. There was no significant difference in the incidence of incisional hernia or wound dehiscence between the groups. In multivariate Cox proportional hazard analysis, BMI > 25, wound dehiscence, and postoperative wound infection were found to be independent risk factors for incisional hernia (all p < 0.05). In multivariate logistic regression analysis, male gender and chronic obstructive pulmonary disease were risk factors for wound dehiscence (both p < 0.05).

Conclusions

The present study failed to show a significant improvement in rates of incisional hernia and wound dehiscence after the introduction of Small Stitch Small Bites. When introducing a new standardized technique for closing the abdomen, education and structural implementation of guidelines may have an impact in the long run. The risk factors identified should be taken into consideration when closing a midline incision to identify patients with high risk.
Comparison of pleural drain amylase and serum C-reactive protein for early detection of intrathoracic esophago-gastric anastomotic leaks
Authors: Andreatta Erika , Buogo Alberto , Asti Emanuele , Boveri Sara , Bonavina Luigi
Published: May 2022

Introduction

Early detection of anastomotic leaks following esophagectomy has the potential to reduce hospital length of stay and mortality. The aim of this study was to compare the predictive value of pleural drain amylase and serum C-reactive protein for the early diagnosis of leak.

Methods

A retrospective observational cohort study was conducted on 121 patients who underwent Ivor Lewis esophagectomy and intrathoracic gastric conduit reconstruction. Pleural drain amylase levels were measured daily until postoperative day (POD) 5 and compared with CRP values measured on POD 3, 5, and 7. Specificity and sensitivity for both tests, and the respective ROC curves, were calculated.

Results

Anastomotic leak occurred in 12 patients. There was a significant statistical association between pleural drain amylase and serum CRP levels and the presence of anastomotic leakage. Pleural drain amylase cutoff of 209 IU/L on POD 2 yielded a sensitivity of 75% and a specificity of 94% (AUC = 0.813), whereas CRP cutoff value of 22.5 mg/dL on POD 3 yielded a sensitivity of 56% and a specificity of 92% (AUC = 0.772). The negative likelihood ratio of pleural drain amylase was 0.27 and 0.12 on POD 2 and 5, respectively. There was no statistically significant difference between ROC curves of amylase and CRP on POD 3 and 5 (p = 0.79 and p = 0.14, respectively).

Conclusions

Pleural drain amylase seems more efficient than serum CRP for early detection of esophago-gastric anastomotic leak. The practice of monitoring drain amylase and CRP may allow safer implementation of enhanced postoperative recovery pathway.
Frailty assessment tools predict perioperative outcome in elderly patients with endometrial cancer better than age or BMI alone: a retrospective observational cohort study
Authors: Anic Katharina , Flohr Friedrich , Schmidt Mona Wanda , Krajnak Slavomir , Schwab Roxana , Schmidt Marcus , Westphalen Christiane , Eichelsbacher Clemens , Ruckes Christian , Brenner Walburgis , Hasenburg Annette , Battista Marco Johannes
Published: May 2022

Objective

Five commonly used global health assessment tools have been evaluated to identify and assess the preoperative frailty status and its relationship with perioperative in-hospital complications and transfusion rates in older women with endometrial cancer (EC).

Methods

Preoperative frailty status was examined by the G8 questionnaire, the Eastern Cooperative Oncology Group performance status, the Charlson Comorbidity Index and the American Society of Anesthesiologists Physical Status System, as well as the Lee-Schonberg prognostic index. The main outcome measures were perioperative laboratory values, intraoperative surgical parameters and immediately postoperative complications.

Results

153 consecutive women ≥ 60 years with all stages of EC, who received primary elective surgery at the University Medical Center Mainz between 2008 and 2019 were classified with selected global health assessment tools according to their preoperative performance status. In contrast to conventional prognostic parameters like older age and higher BMI, increasing frailty was significantly associated with preoperative anemia and perioperative transfusions (p < 0.05). Moreover, in patients preoperatively classified as frail significantly more postoperative complications (G8 Score: frail: 20.7% vs. non-frail: 6.7%, p = 0.028; ECOG: frail: 40.9% vs. non-frail: 2.8%, p = 0.002; and CCI: frail: 25.0% vs. non-frail: 7.4%, p = 0.003) and an increased length of hospitalization were recorded. According to propensity score matching, the risk for developing postoperative complications for frail patients was approximately two-fold higher, depending on which global health assessment tool was used.

Conclusions

Preoperatively assessed frailty significantly predicts post-surgical morbidity rates in contrast to conventionally used single prognostic parameters such as age or BMI. A standardized preoperative assessment of frailty in the routine work-up might be beneficial in older cancer patients before major surgery to include these patients in a prehabilitation program with nutrition counseling and physiotherapy to adequately assess the perioperative risk.
Top 10 research priorities in colorectal cancer: results from the Colorectal Cancer Priority-Setting Partnership
Authors: Klotz Rosa , Holze Magdalena , Dörr-Harim Colette , Grohmann Erich , Nied Barbara , Lebert Burkhard , Weg-Remers Susanne , Lutz Claudia , Meißler Karin , Schloss Patrick , Ullrich Charlotte , Frankenhauser Susanne , Lutter Heidi , Bühler Diedrich , Ahmed Azaz , Gronlund Toto , Mihaljevic André L. ,   for the Forschungspartnerschaft Darmkrebs (www.forschungspartnerschaft.de), Mihaljevic André , Klotz Rosa , Dörr-Harim Colette ,   Steering Group Forschungspartnerschaft Darmkrebs/Priority Setting Colorectal Cancer, Bühler Diedrich , Dörr-Harim Colette , Frankenhauser Susanne , Gapp-Frasch Sylvia , Grohmann Erich , Helmstädter Volker , Hey Christa , Hey Werner , Klotz Rosa , Mihaljevic André , Lebert Burkhard , Lutz Claudia , Lutter Heidi , Lutz Claudia , Meißler Karin , Nied Barbara , Schloss Patrick , Stegmüller Susanne , Stünzi Peter , Trabold-Hauk Angelika , Ullrich Charlotte , Weg-Remers Susanne , Wensing Michel
Published: May 2022

Background

Colorectal cancer (CRC) is the third most frequent cause of cancer death in the word. Which aspects of research into CRC should be accorded the highest priority remains unclear, because relevant stakeholders, such as patients, nurses, and physicians, played hardly any part in the development of research projects. The goal in forming the CRC Priority-Setting Partnership (PSP) was to bring all relevant stakeholders together to identify and prioritize unresolved research questions regarding the diagnosis, treatment, and follow-up of CRC.

Methods

The CRC PSP worked in cooperation with the British James Lind Alliance. An initial nationwide survey was conducted, and evidence uncertainties were collected, categorized, summarized, and compared with available evidence from the literature. The as-yet unresolved questions were (provisionally) ranked in a second national wide survey, and at a concluding consensus workshop all stakeholders came together to finalize the rankings in a nominal group process and compile a top 10 list.

Results

In the first survey (34% patients, 51% healthcare professionals, 15% unknown), 1102 submissions were made. After exclusion of duplicates and previously resolved questions, 66 topics were then ranked in the second survey (56% patients, 39% healthcare professionals, 5% unknown). This interim ranking process revealed distinct differences between relatives and healthcare professionals. The final top 10 list compiled at the consensus workshop covers a wide area of research topics.

Conclusion

All relevant stakeholders in the CRC PSP worked together to identify and prioritize the top 10 evidence uncertainties. The results give researchers and funding bodies the opportunity to address the most patient-relevant research projects. It is the first detailed description of a PSP in Germany, and the first PSP on CRC care worldwide.
Linial for lists
Authors: Maus Yannic , Tonoyan Tigran
Published: May 2022

Linial’s famous color reduction algorithm reduces a given m-coloring of a graph with maximum degree $$\varDelta $$
Δ
to an $$O(\varDelta ^2\log m)$$

O
(

Δ
2

log
m
)

-coloring, in a single round in the LOCAL model. We give a similar result when nodes are restricted to choose their color from a list of allowed colors: given an m-coloring in a directed graph of maximum outdegree $$\beta $$
β
, if every node has a list of size $$\varOmega (\beta ^2 (\log \beta +\log \log m + \log \log |{\mathcal {C}}|))$$

Ω
(

β
2

(
log
β
+
log
log
m
+
log
log
|
C
|
)
)

from a color space $${\mathcal {C}}$$
C
then they can select a color in two rounds in the LOCAL model. Moreover, the communication of a node essentially consists of sending its list to the neighbors. This is obtained as part of a framework that also contains Linial’s color reduction (with an alternative proof) as a special case. Our result also leads to a defective list coloring algorithm. As a corollary, we improve the state-of-the-art truly local$$({\text {deg}}+1)$$

(
deg
+
1
)

-list coloring algorithm from Barenboim et al. (PODC, pp 437–446, 2018) by slightly reducing the runtime to $$O(\sqrt{\varDelta \log \varDelta })+\log ^* n$$

O

(

Δ
log
Δ

)

+

log
∗

n

and significantly reducing the message size (from $$\varDelta ^{O(\log ^* \varDelta )}$$

Δ

O
(

log
∗

Δ
)

to roughly $$\varDelta $$
Δ
). Our techniques are inspired by the local conflict coloring framework of Fraigniaud et al. (in: FOCS, pp 625–634, 2016).
Totally extraperitoneal laparoscopic inguinal hernia repair post-radical prostatectomy
Authors: Watt Imogen , Bartlett Adam , Dunn John , Bowker Andrew
Published: May 2022

Background

Previous radical prostatectomy (RP) is considered a relative contraindication to the laparoscopic approach for inguinal hernia repair (LIHR). This study aimed to compare feasibility, safety and outcomes for patients undergoing totally extraperitoneal (TEP) LIHR who have previously undergone RP.

Methods

This single surgeon, case–control study was performed using a prospective database of all patients undergoing TEP LIHR between 1995 and 2020. Patients who underwent previous RP were identified and compared to matched controls. Pre-operative, operative and post-operative data were analysed. The type of RP, open, laparoscopic or robotic, was identified and operative outcomes compared between the three groups.

Results

6532 LIHR cases were identified. 165 had previously undergone RP and 6367 had undergone primary LIHR without prior RP. The groups were matched for age, demographics and co-morbidities. All operations were commenced laparoscopically, three converted to open in the LIHR + RP group and none in the LIHR group. Median operative time in patients with previous RP was longer, for unilateral (40 min vs. 21 min, p < 0.0001) and bilateral (71 vs. 30 min, p < 0.0001) LIHR. The majority of cases were performed as day stay procedures. There was no difference in immediate recovery parameters including time to discharge, complication rates, return to normal function, return to driving or post-operative analgesia. At 3 months of follow-up there was no difference in hernia recurrence for unilateral (2/128 vs 6/2234, p = 0.0658) or bilateral (0/24 vs 3/1490, p ≥ 0.999) LIHR, nor chronic pain as measured by patient awareness or restriction of activity. No differences in operative and post-operative outcomes were identified between the three types of RP, other than difference in operative time (p = 0.0336).

Conclusions

Previous RP should not be an absolute contraindication for TEP LIHR. Although previous RP adds complexity, in experienced hands TEP LIHR can be done safely, with outcomes equivalent to patients who have not previously undergone RP.
Complete genome sequence of a novel potyvirus infecting Miscanthus sinensis (silver grass)
Authors: Leblanc Zacharie , Gauthier Marie-Emilie , Lelwala Ruvini , Elliott Candace , McMaster Cassie , Eichner Robin , Davis Kevin , Liefting Lia , Thompson Jeremy , Dinsdale Adrian , Whattam Mark , Pattemore Julie , Barrero Roberto A.
Published: May 2022

Here, we describe the full-length genome sequence of a novel potyvirus, tentatively named “Miscanthus sinensis mosaic virus” (MsiMV), isolated from Miscanthus sinensis (silver grass) held in a post-entry quarantine facility after being imported into Western Australia, Australia. The MsiMV genome is 9604 nucleotides (nt) in length, encoding a 3071-amino-acid (aa) polyprotein with conserved sequence motifs. The MsiMV genome is most closely related to that of sorghum mosaic virus (SrMV), with 74% nt and 78.5% aa sequence identity to the SrMV polyprotein region. Phylogenetic analysis based on the polyprotein grouped MsiMV with SrMV, sugarcane mosaic virus (SCMV), and maize dwarf mosaic virus (MDMV). This is the first report of a novel monopartite ssRNA virus in Miscanthus sinensis related to members of the genus Potyvirus in the family Potyviridae.
LED-Based Photo-CIDNP Hyperpolarization Enables 19F MR Imaging and 19F NMR Spectroscopy of 3-Fluoro-DL-tyrosine at 0.6 T
Authors: Bernarding Johannes , Bruns Christian , Prediger Isabell , Plaumann Markus
Published: May 2022

Although 19F has high potential to serve as a background-free molecular marker in bioimaging, the molar amount of marker substance is often too small to enable 19F MR imaging or 19F NMR spectroscopy with a sufficiently high signal-to-noise ratio (SNR). Hyperpolarization methods such as parahydrogen-based hyperpolarization or dynamic nuclear polarization (DNP) can significantly improve the SNR, but require expensive and complex sample preparation and the removal of toxic catalysts and solvents. Therefore, we used the biologically compatible model of the fluorinated amino acid 3-Fluoro-DL-tyrosine with riboflavin 5ʹ-monophosphate (FMN) as a chromophore dissolved in D2O with 3.4% H2Odest., allowing to transform light energy into hyperpolarization of the 19F nucleus via photo-chemically induced dynamic nuclear polarization (photo-CIDNP). We used a low-cost high-power blue LED to illuminate the sample replacing traditionally used laser excitation, which is both potentially harmful and costly. For the first time, we present results of hyperpolarized 19F MRI and 19F NMR performed with a low-cost 0.6 T benchtop MRI system. The device allowed simultaneous dual-channel 1H/19F NMR. 19F imaging was performed with a (0.94 mm)2 in-plane resolution. This enabled the spatial resolution of different degrees of hyperpolarization within the sample. We estimated the photo-CIDNP-based 19F signal enhancement at 0.6 T to be approximately 465. FMN did not bleach out even after multiple excitations, so that the signal-to-noise ratio could be further improved by averaging hyperpolarized signals. The results show that the easy-to-use experimental setup has a high potential to serve as an efficient preclinical tool for hyperpolarization studies in bioimaging.
Teilnahmeinteresse, Wünsche und Visionen österreichischer Psychotherapeut_innen zur Psychotherapieforschung – Ergebnisse einer Online-Befragung
Authors: Figl Christin , Laireiter Anton-Rupert
Published: May 2022

Praxisorientierte Psychotherapieforschung benötigt die Erfahrung, Sichtweisen und Mitarbeit praktizierender Psychotherapeut_innen. Es ist erstaunlich, dass bisher erst eine bereits 15 Jahre alte Studie über die Einstellung österreichischer Psychotherapeut_innen zur Psychotherapieforschung existiert. Um diese Forschungslücke zu schließen, wurden in einer Onlinestudie das Teilnahmeinteresse und die Wünsche und Visionen von österreichischen Psychotherapeut_innen (N = 855; 72.8 % Frauen, 28 bis 80 Jahre) zur Psychotherapieforschung erhoben. Die Ergebnisse zeigen, dass ein generelles Interesse an Studienteilnahmen besteht. Eine stärkere Förderung von Psychotherapieforschung wird stark unterstützt. Eine Ablehnung von Studienteilnahmen wurde primär mit Zeitmangel begründet und eine Belohnung für Teilnahmen gewünscht. Ein positives Erleben von Anfragen, bisherige Studienteilnahmen, eine positive Einstellung und ein weniger stark ausgeprägtes forschungskritisches professionelles Selbstverständnis konnten die Teilnahmebereitschaft signifikant vorhersagen. Therapeut_innen‑, Wirkfaktoren- und Wirksamkeitsstudien, qualitative oder kombiniert quantitativ-qualitative Methoden, Schulen übergreifende Fragstellungen sowie die Durchführung von Studien durch interdisziplinäre Teams oder Psychotherapeut_innen im Kontext von Psychotherapieforschungsinstituten erwiesen sich als die stärksten Motivatoren für Studienteilnahmen. Die Ergebnisse bieten Anknüpfungspunkte für Psychotherapiestudien: Einbezug und Berücksichtigung von Psychotherapeut_innen-Interessen, eine verstärkte Aufklärung über Möglichkeiten, sich an Forschungsprojekten zu beteiligen und eine adäquate Belohnung für Studienteilnahmen.
Fine-grained semantic type discovery for heterogeneous sources using clustering
Authors: Piai Federico , Atzeni Paolo , Merialdo Paolo , Srivastava Divesh
Published: May 2022

We focus on the key task of semantic type discovery over a set of heterogeneous sources, an important data preparation task. We consider the challenging setting of multiple Web data sources in a vertical domain, which present sparsity of data and a high degree of heterogeneity, even internally within each individual source. We assume each source provides a collection of entity specifications, i.e. entity descriptions, each expressed as a set of attribute name-value pairs. Semantic type discovery aims at clustering individual attribute name-value pairs that represent the same semantic concept. We take advantage of the opportunities arising from the redundancy of information across such sources and propose the iterativeRaF-STDsolution, which consists of three key steps: (i) a Bayesian model analysis of overlapping information across sources to match the most locally homogeneous attributes; (ii) a tagging approach, inspired by NLP techniques, to create (virtual) homogeneous attributes from portions of heterogeneous attribute values; and (iii) a novel use of classical techniques based on matching of attribute names and domains. Empirical evaluation on the DI2KG and WDC benchmarks demonstrates the superiority ofRaF-STDover alternative approaches adapted from the literature.
Simulated and clinical aerosol spread in common periodontal aerosol-generating procedures
Authors: Puljich Anthony , Jiao Kexin , Lee Ryan S. B. , Walsh Laurence J. , Ivanovski Sašo , Han Pingping
Published: May 2022

Objectives

This study evaluated particle spread associated with various common periodontal aerosol-generating procedures (AGPs) in simulated and clinical settings.

Materials and methods

A simulation study visualized the aerosols, droplets, and splatter spread with and without high-volume suction (HVS, 325 L/min) during common dental AGPs, namely ultrasonic scaling, air flow prophylaxis, and implant drilling after fluorescein dye was added to the water irrigant as a tracer. Each procedure was repeated 10 times. A complementary clinical study measured the spread of contaminated particles within the dental operatory and quantified airborne protein dispersion following 10 min of ultrasonic supragingival scaling of 19 participants during routine periodontal treatment.

Results

The simulation study data showed that air flow produced the highest amount of splatters and the ultrasonic scaler generated the most aerosol and droplet particles at 1.2 m away from the source. The use of HVS effectively reduced 37.5–96% of splatter generation for all three dental AGPs, as well as 82–93% of aerosol and droplet particles at 1.2 m for the ultrasonic scaler and air polisher. In the clinical study, higher protein levels above background levels following ultrasonic supragingival scaling were detected in fewer than 20% of patients, indicating minimal particle spread.

Conclusions

While three common periodontal AGPs produce aerosols and droplet particles up to at least 1.2 m from the source, the use of HVS is of significant benefit. Routine ultrasonic supragingival scaling produced few detectable traces of salivary protein at various sites throughout the 10-min dental operatory.

Clinical relevance

The likelihood of aerosol spread to distant sites during common periodontal AGPs is greatly reduced by high-volume suction. Clinically, limited evidence of protein contaminants was found following routine ultrasonic scaling, suggesting that the the majority of the contamination consisits of the irrigant rather than organic matter from the oral cavity.
Development of the dog executive function scale (DEFS) for adult dogs
Authors: Foraita Maike , Howell Tiffani , Bennett Pauleen
Published: May 2022

Executive functions (EFs) are cognitive processes that are used to effortfully self-regulate behaviour and might be important for dogs’ success in working and pet roles. Currently, studies are assessing dogs’ EF skills through often laborious cognitive measures, leading to small sample sizes and lacking measures of reliability. A complementary method is needed. The aim of this study was to develop a dog executive function scale (DEFS) for adult dogs. Focus groups were held with people working with dogs professionally to refine a pool of items describing dog behaviours related to EF. A survey was distributed online to a convenience sample of N = 714 owners of adult dogs. Exploratory and confirmatory factor analysis identified six distinguishable factors named behavioural flexibility, motor inhibition, attention towards owner, instruction following, delay inhibition and working memory. These factors appear similar to factors identified in human EF scales. Working dogs exhibit higher EF scores on the DEFS than non-working dogs. Dogs sourced from breeders exhibited higher DEFS scores than dogs sourced from shelters, and the amount of training received positively correlated with dogs’ DEFS scores. The DEFS requires further validation with cognitive measures. The DEFS could then be used by researchers to complement assessment of dogs’ EF skills through cognitive measures or assess dogs’ EF skills in large samples.
Context specificity of latent inhibition in the snail Cornu aspersum
Authors: Muñiz-Moreno Judit , Loy Ignacio
Published: May 2022

The present study was conducted to assess the context specificity of latent inhibition (LI) in the snail Cornu aspersum, using the appetitive Pavlovian Conditioning procedure of tentacle lowering. Snails experienced an odorous conditioned stimulus (CS) without any consequence before being conditioned with food. The conditioned stimulus preexposure occurred in the same context than the conditioning and the test context or in the different context. The study was performed in two replicas in which the photoperiod was defined by level of illumination and time of day (circadian replica) or was defined only by light (light replica). Both replicas showed that the CS preexposure in the same context as conditioning produced a delay in the acquisition of the conditioned response (CR). However, when the CS preexposure took place in a different context than the conditioning context, an equivalent level of CR as that observed in controls without preexposition to CS was shown. These results are congruent with context specificity of LI and they provide the first evidence of this phenomenon in terrestrial mollusks. Learning processes and theories involved in this phenomenon are also debated in the paper.
Climate warming in the Himalayas threatens biodiversity, ecosystem functioning and ecosystem services in the 21st century: is there a better solution?
Authors: Kattel Giri R
Published: May 2022

Biodiversity losses can lead to global environmental crisis. Humans utilize biodiversity for a variety of ecosystem services. However, what drives biodiversity losses have become a critical question during the 21st century. Lately, the Hindu Kush Himalayan (HKH) region in Asia, one of the world’s pristine habitats with the origin of majestic river systems including Brahmaputra, Indus, Mekong, and Yangtze, has witnessed rapid climatic warming. The unprecedented rates of climate warming in HKH has threatened biodiversity losses, ecosystem functioning and ecosystem services, and consequently the existence of mankind in the region. The Intergovernmental Panel on Climate Change (IPCC) and the Intergovernmental Science and Policy Platform on Biodiversity and Ecosystem Services (IPBES) highlight the risks to humanity arising from unsustainable use of natural resources and loss of biodiversity worldwide under rapid climate warming condition. In addition, the growing economic transformation in HKH can have high environmental costs and biodiversity losses. By realizing this fact, the Convention on Biological Diversity addresses the key issues of biodiversity and ecosystem services in the HKH by liaising with the United Nations Framework Convention on Climate Change, Paris Agreement, and the Sustainable Development Goals (SDGs). Hence, the challenges of biodiversity losses, poor ecosystem functioning followed by reduced ecosystem services posed by climate warming and anthropogenic impacts needs to be addressed urgently by countries and multilateral agencies in HKH by identifying threatened ecosystem services and by providing better sustainability solutions. Here, I have outlined the current state of Himalayan biodiversity and ecosystem function and developed a framework for resilience management with an integrated approach of science and society to advance knowledge through learning. The resilience framework offers practical solutions comprising a robust and harmonized monitoring of climatic data, the use of multi-indicator approaches and modelling, and to make collaborated efforts among policy makers, implementers, and analysts to tackle evolving losses of biological diversity and reduction in ecosystem services in the HKH region.
What is the concordance between parent- and education professional-reported adaptive functioning in autistic children using the VABS-II?
Authors: Moore Heather L. , Couteur Ann Le , Charman Tony , Green Jonathan , Parr Jeremy R , Grahame Victoria
Published: May 2022

Adaptive functioning of autistic children is traditionally measured through informant-report, often from parents. Behaviour varies across settings though, and context-specific reports should be considered. Limited and inconsistent results show low parent-education professional concordance, but no research has yet explored item level response variation. We investigated Vineland Adaptive Behaviour Scales-II concordance using 233 lower ability autistic children from the PACT-G sample. Domain and item level agreement was low, but better on objectively measured behaviours. Higher child nonverbal ability improved concordance. Where disagreements occurred, education professionals identified emergent skills more and parents were more likely to rate present/absent. Parents and education professionals view the adaptive abilities of autistic children differently and both should be considered when developing personalised interventions and support.
Design Space Survey on Social Robotics in the Market
Authors: Ramírez Valentina , Deuff Dominique , Indurkhya Xela , Venture Gentiane
Published: May 2022

Socially interactive robots are being introduced in daily life as common objects that facilitate people’s life. A wide range of possibilities are offered and the trends show a growing market. In this survey 40 commercial robots were analysed to evaluate the state of the art from a design space perspective, aspects like embodiment, task, social role, context of use, DOF (Degrees of Freedom) and user studies performed on the robot are included. As a result, a clear design pattern was identified: an egg-shaped, white plastic robot with a rendered face that displays expression of emotions and a speech interface is the common base of the majority of the social robots available in the market. The preference for this kind of embodiment is not even studied nor documented in the literature and varies according to the target group and culture.
AFE-ORB-SLAM: Robust Monocular VSLAM Based on Adaptive FAST Threshold and Image Enhancement for Complex Lighting Environments
Authors: Yu Leijian , Yang Erfu , Yang Beiya
Published: May 2022

Monocular Visual Simultaneous Localisation and Mapping (VSLAM) systems are widely utilised for intelligent mobile robots to work in unknown environments. However, complex and varying illuminations challenge the accuracy and robustness of VSLAM systems significantly. Existing feature-based VSLAM methods often fail due to the insufficient feature points that can be extracted in those challenging illumination environments. Therefore, this paper proposes an improved ORB-SLAM algorithm based on adaptive FAST threshold and image enhancement (AFE-ORB-SLAM), which works in the environments with complex lighting conditions. An improved truncated Adaptive Gamma Correction (AGC) is combined with unsharp masking to reduce the effect caused by different illuminations. What is more, an improved ORB feature extraction method with the adaptive FAST threshold is proposed and adopted to obtain more reliable feature points. To verify the performance of the AFE-ORB-SLAM, three public datasets (the extended Imperial College London and National University of Ireland Maynooth (ICL-NUIM) dataset with different lighting conditions, Onboard Illumination Visual-Inertial Odometry (OIVIO) dataset and the European Robotics Challenge (EuRoC) dataset) are utilised. The results are compared with other state-of-the-art monocular VSLAM methods. The experimental results demonstrate that the AFE-ORB-SLAM could achieve the highest average localisation accuracy with robust performance in the environments with complex lighting conditions while keeping similar performance in the normal lighting scenarios.
Gambling: Exploring the Role of Gambling Motives, Attachment and Addictive Behaviours Among Adolescents and Young Women
Authors: Macía L. , Estévez A. , Jáuregui P.
Published: May 2022

There is a growing body of research that seeks to understand the aetiology, consequences and risk factors associated with addictive behaviours in youths. However, research examining the specific profile of adolescent females is very limited. Therefore, the objectives of the present study were, firstly, to explore the differences between attachment, gambling motives (social enhancement and coping), positive and negative affect, and addictive behaviours (gambling, drugs, spending, alcohol and video games) in female adolescents with and without risk of gambling problems. Secondly, the relationships between attachment, gambling motives, positive and negative affect and addictive behaviours were analysed in the subsample of female adolescents with problem gambling Thirdly, we examine the predictive role of positive and negative affect, gambling motives, and attachment in the aforementioned addictive behaviours. The sample was composed of 351 adolescents and young women, of which 312 had no risk of gambling and 39 had gambling problems. The results obtained revealed higher scores in drugs, spending, maternal attachment, and all gambling motives in the group of gambling problems. Likewise, analyses showed that the relevance of the predictor variables (attachment, gambling motives, and affect) varied according to the addiction that was taken as a reference point (i.e., gambling, drugs, spending, alcohol and video games).Consequently, the identification of the possible vulnerability factors for each addiction could be useful in the design of prevention and treatment approaches. In addition, the need for integrated and holistic health- and social- care programmes are suggested in terms of sex and age.
Towards enhanced PDF maldocs detection with feature engineering: design challenges
Authors: Falah Ahmed , Pokhrel Shiva Raj , Pan Lei , de Souza-Daw Anthony
Published: May 2022

In this paper, we perform an in-depth analysis of a large corpus of PDF maldocs to identify the key set of significantly important features and help in maldoc detection. Existing industry-based tools for the detection are inefficient and cannot prevent PDF maldocs because they are generic and depend primarily on a signature-based approach. Besides, several other methods developed by academics suffer heavily from reduced effectiveness. The feature-set using machine learning classifiers is prone to various known attacks, such as mimicry and parser confusion. Also, we discover that increasingly more malicious files i) contain evasive and obfuscated JavaScript code, ii) include hidden contents (mostly outside the objects), iii) have a corrupted document structure, and iv) usually contain short JavaScript code blocks. We utilise maldoc attacks’ evolution over a decade to highlight the essential features (e.g., concept drifts) that impact detectors and classifiers.
Cattle dung and bioturbation by dung beetles improve oak seedling establishment in Mediterranean silvopastoral ecosystems
Authors: Leiva María José , Sobrino-Mengual Guillermo
Published: May 2022

This study aims to determine whether the application of cattle manure and associated bioturbation by dung beetles and other invertebrates can increase oak seedling establishment in the high biodiversity Mediterranean silvopastoral systems known as “dehesas”, which are comprised of scattered oaks and a grassland layer and are used for livestock rearing. A two-year study was conducted in a representative dehesa in southern Spain. Firstly, the effect of cattle dung pads on acorn consumption by livestock and wild predators was monitored, along with dung beetle abundance and plot bioturbation. Secondly, the indirect effects of bioturbation on acorn burial, acorn predation by rodents and oak seedling establishment were assessed under the condition of livestock exclusion. The results consistently demonstrate a high positive indirect effect of the presence of cattle manure on the persistence of acorns, as well as on seedling establishment, as a result of reduced predation by rodents and improved microhabitat conditions for the acorns and seedlings. These processes were mediated by bioturbation. Tunneler dung beetles, which move a great amount of soil material, were dominant in our records, which suggest their importance for passive acorn burial, without disregarding the influence of other edaphic invertebrates present. We conclude that the presence of cattle manure significantly improves oak seedling establishment in Mediterranean dehesas through the passive burial of acorns by bioturbation, which acts to protect them from predation by rodents, desiccation and other damage. Passive acorn burial by dung beetles and other invertebrates thus emerges as an important ecosystem service that has been little-studied to date. Appropriate rotational management of livestock could therefore contribute to addressing the bottleneck of oak regeneration in Mediterranean dehesas.
Silicon accumulation suppresses arbuscular mycorrhizal fungal colonisation in the model grass Brachypodium distachyon
Authors: Johnson Scott N. , Powell Jeff R. , Frew Adam , Cibils–Stewart Ximena
Published: May 2022

Purpose

Silicon (Si) accumulation by grasses alleviates diverse biotic and abiotic stresses. Despite this important functional role, we have limited understanding of how root microbial symbionts, such as arbuscular mycorrhizal (AM) fungi, affect Si uptake and even less about how Si supply and accumulation affect AM fungal colonisation. Our objective was to determine the nature of this two–way interaction in the model grass, Brachypodium distachyon.

Methods

We grew B. distachyon with five levels of Si supplementation using wild-type plants and a mutant (Bdlsi1-1) that has little capacity for Si uptake. Half of the plants were colonised by AM fungi; half were free of AM fungi. We measured Si accumulation, AM fungal colonisation, leaf carbon (C), nitrogen (N) and phosphorus (P) concentrations.

Results

AM fungi did not affect Si accumulation, although small increases occurred when root mass was included as a covariate. Si supplemented soil promoted plant growth and P uptake. Si accumulation suppressed colonisation by AM fungi and C concentrations in wild type but not in Bdlsi1-1 plants. Si concentrations were negatively correlated with C and N concentrations, with correlations being stronger in wild-type plants than Bdlsi1-1 plants.

Conclusions

Our results indicate that Si accumulation in the plant, rather than Si availability in the soil, underpinned reduced AMF colonisation. We propose that Si accumulation is unlikely to be impacted by AM fungi in plants with inherently high Si accumulation, but Si accumulation may suppress AM fungal colonisation in such plants.