bluuebunny/crossref_metadata_2025 huggingface dataset:
Organochlorine Compounds in Common Carp (Cyprinus carpio) from Patagonia Argentina
Authors: Ondarza P. M. , Miglioranza K. S. B. , Gonzalez M. , Shimabukuro V. M. , Aizpún J. E. , Moreno V. J.
Published: September 2010

The Negro River is the most important hydrological system of Patagonia, Argentina, drains a watershed of 140,000 km2. Its main economic activities are agriculture and industry, representing potential sources of organochlorine compounds (OCCs): organochlorine pesticides (OCPs) and PCBs, respectively. These pollutants are persistent, ubiquitous and hydrophobics and are accumulated in the lipid fraction of biota. Fish are excellent biomonitors of pollution because incorporate COCs from water and through diet, and represent different trophic levels. The aims of the present study were to investigate OCCs levels in wild common carp, Cyprinus carpio (Cyprynidae) focusing on: a) the distribution pattern of OCPs and PCBs in gills, gonads, liver, muscle, and stomach content, b) the potential of common carp as indicator of aquatic OCCs pollution, and c) the evaluation of residues in gills and stomach content to discuss different input pathways of OCCs. HCHs, Chlordanes, DDTs, Endosulfan, Heptachlors, Drines and PCBs were quantified by GC-ECD. The distribution of OCCs (ng.g–1 lipid) was gills> gonads> liver> muscle> stomach content. Endosulfan accounted for 64% of OCCs in gills while, DDTs, PCBs and Chlordanes predominated in the stomach content suggesting the incorporation of more hydrophilic pollutants from the water column and those most persistent and hydrophobic from the diet.
Determination of Antimony, Arsenic, Cadmium and Thorium in Sugar Cane Juice Obtained from Cropland Treated with Sewage Sludge
Authors: Armelin M. J. A. , Abreu Jr. C. H. , Catharino M. G. M. , Saiki M. , Ribeiro A. C. S. , Franco A. , Fernandes H. M. G.
Published: September 2010

Concern regard environmental quality and human health demands wastewater treatment technology and in this treatment, sewage sludge is generated. This sewage sludge, after a properly microorganism reduction and physically conditioning, is usually known as biosolid. One of the alternatives to the final destination of this waste is the its application in agricultural land, as fertilizer. The objectives of this study were: biosolid multielemental characterization and determination of As, Cd, Sb and Th concentrations in sugar cane juice obtained from plant that was grown in soil treated with this biosolid. Instrumental neutron activation analysis (INAA) was applied to evaluate the elemental concentrations. Elemental concentrations for As, Br, Ca, Cd, Co, Cr, Eu, Fe, La, Mg, Mn, Mo, K, Na, Sb, Sc, Sm, Th, Ti, U, V and Zn are presented for biosolid. Analysis of sugar cane juice showed no significant difference in the concentration of As, Sb, and Th with the doses of biosolid (0; 3.6; 7.2 and 10.8 t.ha–1, dry base), except for Cd, at the dose of 10.8 t.ha–1.
Phytoplanktonic Structure and Chemistry of the Water in the Monjolinho Reservoir (SP, Brazil) During a Cyanobacterial Bloom Episode
Authors: Sotero-Santos R. B. , Dellamano-Oliveira M. J. , Carvalho E. G. , Minillo A. , Rocha O.
Published: September 2010

The composition of the phytoplankton and parameters of the water quality were studied in a tropical reservoir during cyanobacterial bloom episode. Samples were collected at two sites during October 2004. The phytoplankton community consisted of 69 taxa, distributed into 9 classes. Most taxa belonged to Cyanobacteria (17), Chlorophyceae (21), Bacillariophyceae (8), Conjugatophyceae (7), Dinophyceae (1), Chrysophyceae (4), Euglenophyceae (9), Cryptophyceae (1) and Xanthophyceae (1). Anabaena circinalis Rabenhorst ex Bornet et Flahault e Anabaena spiroides Klebahn were the dominant species. Statistical analyses revealed significant spatial variation (p < 0.05) between sampling points only for N compounds and chlorophyll a. Most limnological variables analyzed showed no significant temporal variation (p > 0.05). Cyanobacteria bloom was concomitant with the following environmental conditions, warm water temperatures (19 to 22 oC), periods of water column stability and high concentrations of N (724.9 Î¼g.L-1) and P (90.9 Î¼g.L-1) in the reservoir and NH4 as being the predominant nitrogen compounds. It is speculated that those conditions could play a role in the dominance of cyanobacteria.
Investigating the effect of previous treatments on wheat biomass over multiple spatial frequencies
Authors: Milne A. E. , Castellanos M. T. , Cartagena M. C. , Tarquis A. M. , Lark R. M.
Published: September 2010

Abstract. In this study we use the maximum overlap discrete packet transform (MODWPT) to investigate residual effects on wheat biomass of fertigation treatments applied to a previous crop. The wheat crop covered nine subplots from a previous experiment on melon response to fertigation. Each subplot had previously received a different level of applied nitrogen. Many factors affect wheat biomass, causing it to vary at different spatial frequencies. We hypothesize that these will include residual effects from fertilizer application (at relatively low spatial frequencies) and the local influence of individual plants from the previous melon crop (at high frequency). To test this hypothesis we use the MODWPT to identify the dominant spatial frequencies of wheat biomass variation, and analyse the relationship to both the previous fertilizer application and the location of individual melon plants in the previous crop. The MODWPT is particularly appropriate for this because it allows us first to identify the key spatial frequencies in the wheat biomass objectively and to analyse them, and their relationship to hypothesized driving factors without any assumptions of uniformity (stationarity) of wheat-biomass variation. The results showed that the applied nitrogen dominated the wheat biomass response, and that there was a noticeable component of wheat-biomass variation at the spatial frequency that corresponds to the melon cropping. We expected wheat biomass to be negatively correlated with the position of melons in the previous crop, due to uptake of the applied nitrogen. The MODWPT, which allows us to detect changes in correlation between variables at different frequencies, showed that such a relationship was found across part of the experiment but not uniformly.
Benefitting from differences in knowledge, practice and belief: Māori oral traditions and natural hazards science
Authors: King D. N. , Goff J. R.
Published: September 2010

Abstract. This paper builds upon earlier work that argued the information and experience contained within the knowledge-practice-belief complex of Mātauranga Māori [Māori knowledge] is a valuable and neglected area of information and understanding about past catastrophic events in Aotearoa/New Zealand (A/NZ). Here we map Māori oral traditions (pūrākau) that relate experience with extreme environmental disturbance (in particular, tsunamis) around the A/NZ coast, compare the findings with geo-archaeological evidence, and discuss the scientific benefits to be gained by considering pūrākau as legitimate perspectives on history. Not surprisingly, there are both differences and complementarities between traditional Māori narratives and the available geo-archaeological evidence on extreme coastal disturbances. The findings presented here raise new and important questions about accepted geographies of tsunami risk, the causes and sources of their generation, as well as reasons for the relative paucity and abundance of information in some regions. Ways in which Mātauranga Taiao [Māori environmental knowledge] and contemporary science can be combined to produce new narratives about extreme environmental disturbance along the A/NZ coastline will require not only acceptance of other ways of knowing but also open engagement with Māori that respects their rights to tell their own histories. These efforts are encouraged to revitalise and ground-truth the interpretation of traditional stories, corroborate and/or question previous scientific deductions, and improve our collective understanding of the recurring impact of tectonic, geologic and meteorological-based events across A/NZ.
Citric Acid
Authors: Lopez‐Garcia Rebecca
Published: September 2010

Citric acid is a natural component and common metabolite of plants and minerals. It is the most widely used organic acid in foods, beverages, and pharmaceuticals. Because of its functionality and environmental acceptability, citric acid and its salts are used in many industrial applications for chelation, buffering, pH adjustment, and derivitization. These uses include laundry detergents, shampoos and cosmetics, enhanced oil recovery, and metal cleaning.

This article gives details on the occurrence of citric acid in nature and its physical and chemical properties. Description of the two common methods to recover citric acid from its fermentation broth, lime‐sulfuric acid recovery and liquid extraction are given. Shipment and storage of citric acid are discussed. Various national compendial specifications for citric acid and common analytical methods are discussed. Citric acid as well as its common sodium and potassium salts forms, are considered Generally Recognized as Safe (GRAS). It is biodegraded by many organisms under aerobic and anaerobic waste water treatment conditions and in the natural environment.
Dicarboxylic Acids
Authors: Johnson Robert W. , Pollock Charles M. , Cantrell Robert R.
Published: September 2010

Aliphatic, linear dicarboxylic acids and branched dicarboxylic acids are the subject of this article. These dibasic acids are referred to by their trivial names, IUPAC system or by adding the suffix “dicarboxylic acid“ to the name of the hydrocarbon skeleton. For example a 10‐carbon atom dibasic acid is designated sebacic acid, decanoic or 1,8‐octane‐dicarboxylic acid. Physical and chemical properties of the most common dibasic acids are discussed.

Manufacture and uses for glutaric acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, dodecanoic acid, brassylic acid and C‐19, C‐20, and C‐22 dicarboxylic acids are given.

These diacids are intermediates for the manufacture of diesters, polyesters, and polyamides. These derivatives have many applications ,eg, as plasticizing agents, lubricants, heat‐transfer fuids, inks and coatings, insecticides. Azaleic acid is used in acne preparations. Toxicities and environmental concerns are also discussed.
Intellectual Property In Drug Discovery And Biotechnology
Authors: Maloney Timothy P. , Kaba Richard A. , Krueger James P. , Kratz Rudy , Mitchell Calista J.
Published: September 2010

Intellectual property is the branch of law that protects and, indeed, encourages the creation of certain products of the human mind or intellect. This chapter is intended to provide a basic understanding and appreciation of intellectual property law, especially as it relates to patents, trademarks, and trade secrets, in the United States and, to a lesser extent, in the rest of the world. Issues and concerns particularly related to the drug discovery and development process and the general biotechnology industry are emphasized.
Antipsychotic Agents
Authors: Brown Jeffrey M. , Li Jie Jack , Sinz Michael W.
Published: September 2010

The medicinal chemistry of antipsychotic agents is reviewed in this chapter. The definition of schizophrenia is summarized in two categories, namely, symptom domains and pathology. An overview is given for antipsychotic medications including their clinical applications and side effects. This chapter also describes many animal models for schizophrenia. After an introduction of the FDA approved antipsychotic drugs, the structure–activity relationship, pharmacokinetics, biotransformation, and drug–drug interactions are discussed for both conventional and atypical antipsychotics in details. Finally, eight different strategies for drug discovery of antipsychotics are delineated.
Microbes to Man: From Soils and the Depths to Drugs
Authors: Newman David J. , Cragg Gordon M.
Published: September 2010

The multiplicity of natural product structures produced by single‐celled microbes from all three domains of life has led to very significant numbers of drugs in many human diseases. This chapter demonstrates that even today, approximately 80 years after the seminal work on penicillin, the microbial world is still a cornucopia of novel structures, but now days, rather than using classical fermentation techniques, the full panoply of genomics, biosynthesis, synthetic modification and serendipity is needed to investigate the incalculable potential of these single‐celled organisms so as to unlock their potential as sources of novel scaffolds upon which to “practice the arts of drug discovery and development.”
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
Authors: Harrington Emily P. , Zhao Chao , Fancy Stephen P. J. , Kaing Sovann , Franklin Robin J. M. , Rowitch David H.
Published: September 2010

Objective

Repair of myelin injury in multiple sclerosis may fail, resulting in chronic demyelination, axonal loss, and disease progression. As cellular pathways regulated by phosphatase and tensin homologue deleted on chromosome 10 (PTEN; eg, phosphatidylinositol‐3‐kinase [PI‐3K]) have been reported to enhance axon regeneration and oligodendrocyte maturation, we investigated potentially beneficial effects of Pten loss of function in the oligodendrocyte lineage on remyelination.

Methods

We characterized oligodendrocyte numbers and myelin sheath thickness in mice with conditional inactivation of Pten in oligodendrocytes, Olig2‐cre, Ptenfl/fl mice. Using a model of central nervous system demyelination, lysolecithin injection into the spinal cord white matter, we performed short‐ and long‐term lesioning experiments and quantified oligodendrocyte maturation and myelin sheath thickness in remyelinating lesions.

Results

During development, we observed dramatic hypermyelination in the corpus callosum and spinal cord. Following white matter injury, however, there was no detectable improvement in remyelination. Moreover, we observed progressive myelin sheath abnormalities and massive axon degeneration in the fasciculus gracilis of mutant animals, as indicated by ultrastructure and expression of SMI‐32, amyloid precursor protein, and caspase 6.

Interpretation

These studies indicate adverse effects of chronic Pten inactivation (and by extension, activation PI‐3K signaling) on myelinating oligodendrocytes and their axonal targets. We conclude that PTEN function in oligodendrocytes is required to regulate myelin thickness and preserve axon integrity. In contrast, PTEN is dispensable during myelin repair, and its inactivation confers no detectable benefit. Ann Neurol 2010
Synovial tissue–infiltrating natural killer cells in osteoarthritis and periprosthetic inflammation
Authors: Huss Ryan S. , Huddleston James I. , Goodman Stuart B. , Butcher Eugene C. , Zabel Brian A.
Published: September 2010

Objective

Infiltrating immune cells play a central role in degenerative joint disease associated with osteoarthritis (OA) and particle‐mediated periprosthetic osteolysis. The goal of this study was to characterize a newly identified population of synovial tissue–infiltrating natural killer (NK) cells obtained from patients with OA or patients with periprosthetic joint inflammation.

Methods

Synovial and interfacial tissue samples were collected from patients with OA who were undergoing primary or revision total joint replacement (TJR) surgery. The histologic features of OA synovium obtained from patients undergoing primary surgery and interfacial tissue obtained from patients undergoing revision surgery were determined by immunohistochemistry and immunofluorescence. Synovial tissue–infiltrating NK cells were evaluated for the expression of surface receptors, using flow cytometry. Chemoattractant and cytokine protein and RNA levels in synovial and interfacial tissue and fluid were assessed by Luminex assay and real‐time quantitative polymerase chain reaction. Cytokine production and degranulation by stimulated synovial tissue versus normal blood NK cells were evaluated by intracellular cytokine staining.

Results

NK cells comprised nearly 30% of the CD45+ mononuclear cell infiltrate in synovial tissue obtained from patients undergoing primary TJR and from patients undergoing revision TJR. NK cells from both groups expressed CXCR3, CCR5, L‐selectin, α4 integrins, and cutaneous lymphocyte antigen. Synovial fluid from patients undergoing revision surgery contained elevated concentrations of the NK cell attractants CCL4, CCL5, CXCL9, and CXCL10; all levels in synovial fluid obtained from patients undergoing revision surgery were higher than those in synovial fluid from patients undergoing primary surgery. Cytokine‐stimulated interferon‐γ production was significantly impaired in NK cells derived from primary and revision TJRs compared with blood NK cells.

Conclusion

NK cells are a principal tissue‐infiltrating lymphocyte subset in patients with OA and patients with periprosthetic inflammation and display a quiescent phenotype that is consistent with postactivation exhaustion.
Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus
Authors: Sanchez Elena , Webb Ryan D. , Rasmussen Astrid , Kelly Jennifer A. , Riba Laura , Kaufman Kenneth M. , Garcia‐de la Torre Ignacio , Moctezuma Jose F. , Maradiaga‐Ceceña Marco A. , Cardiel‐Rios Mario H. , Acevedo Eduardo , Cucho‐Venegas Mariano , Garcia Mercedes A. , Gamron Susana , Pons‐Estel Bernardo A. , Vasconcelos Carlos , Martin Javier , Tusié‐Luna Teresa , Harley John B. , Richardson Bruce , Sawalha Amr H. , Alarcón‐Riquelme Marta E.
Published: September 2010

Objective

To assess whether genetically determined Amerindian ancestry predicts increased presence of risk alleles of known susceptibility genes for systemic lupus erythematosus (SLE).

Methods

Single‐nucleotide polymorphisms (SNPs) within 16 confirmed genetic susceptibility loci for SLE were genotyped in a set of 804 Mestizo lupus patients and 667 Mestizo healthy controls. In addition, 347 admixture informative markers were genotyped. Individual ancestry proportions were determined using STRUCTURE. Association analysis was performed using PLINK, and correlation between ancestry and the presence of risk alleles was analyzed using linear regression.

Results

A meta‐analysis of the genetic association of the 16 SNPs across populations showed that TNFSF4, STAT4, ITGAM, and IRF5 were associated with lupus in a Hispanic Mestizo cohort enriched for European and Amerindian ancestry. In addition, 2 SNPs within the major histocompatibility complex region, previously shown to be associated in a genome‐wide association study in Europeans, were also associated in Mestizos. Using linear regression, we predicted an average increase of 2.34 risk alleles when comparing an SLE patient with 100% Amerindian ancestry versus an SLE patient with 0% Amerindian ancestry (P < 0.0001). SLE patients with 43% more Amerindian ancestry were predicted to carry 1 additional risk allele.

Conclusion

Our results demonstrate that Amerindian ancestry is associated with an increased number of risk alleles for SLE.
Controlled Aqueous Solution Synthesis of Platinum–Palladium Alloy Nanodendrites with Various Compositions Using Amphiphilic Triblock Copolymers
Authors: Wang Liang , Yamauchi Yusuke
Published: September 2010

In a recent study, we demonstrated that Pluronic F127 triblock copolymer plays a critical role in the formation of dendritic Pt nanostructures (L. Wang, Y. Yamauchi, J. Am. Chem. Soc. 2009, 131, 9152–9153). Herein, we expand this concept to produce novel dendritic Pt–Pd alloy nanoparticles. In this paper, a very simple, one‐step and efficient route is proposed to directly produce dendritic Pt–Pd alloy nanoparticles with high surface area in high yield, which is carried out simply by stirring an aqueous solution that contains K2PtCl4 and Na2PdCl4 binary precursors in the presence of Pluronic F127 block copolymer and ascorbic acid at room temperature within 30 min without the need for any template, seed‐mediated growth, or additive. By simply changing the compositional ratios of the Pt and Pd sources in the precursor solutions, Pt–Pd nanodendrites with various compositions can be easily produced. Because of its unique simplicity, the proposed approach can be considered as a powerful strategy for producing Pt–Pd alloy nanoparticles with unique nanoarchitectures for commercial devices.
Extending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFs
Authors: Tulin Sarah , Stathopoulos Angelike
Published: September 2010

Since the discovery of fibroblast growth factors (FGFs) much focus has been placed on elucidating the roles for each vertebrate FGF ligand, receptor, and regulating molecules in the context of vertebrate development, human disorders and cancer. Studies in human, mouse, frog, chick, and zebrafish have made great contributions to our understanding of the role of FGFs in specific processes. However, in recent years, as more genomes are sequenced, information is becoming available from many non‐vertebrate models and a more complete picture of the FGF superfamily as a whole is emerging. In some cases, less redundancy in these FGF signaling systems may allow for more mechanistic insights. Studies in sea anemones have highlighted how ancient FGF signaling is and helped provide insight into the evolution of the FGF gene family. Work in nematodes has shown that different splice forms can be used for functional specificity in invertebrate FGF signaling. Comparing FGFs between urochordates and vertebrates as well as between different insect species reveals important clues into the process of gene loss, duplication and subfunctionalization of FGFs throughout evolution. Finally, comparing all members of the FGF ligand superfamily reveals variability in many properties, which may point to a feature of FGFs as being highly adaptable with regards to protein structure and signaling mechanism. Further studies on FGF signaling outside of vertebrates is likely to continue to complement work in vertebrates by contributing additional insights to the FGF field and providing unexpected information that could be used for medical applications. Birth Defects Research (Part C) 90:214–227, 2010. © 2010 Wiley‐Liss, Inc.
Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging
Authors: Mouchiroud Laurent , Molin Laurent , Dallière Nicolas , Solari Florence
Published: September 2010

Life expectancy at the turn of the 20th century was 46 years on average worldwide and it is around 65 years today. The correlative increase in age‐associated diseases incidence has a profound public health impact and is an important matter of concern for our societies. Aging is a complex, heterogeneous, and multifactorial phenomenon, which is the consequence of multiple interactions between genes and environment. In this review, we survey animals models that have been of great help for both investigating mechanism of aging and identifying molecules, which slow down the onset of age‐related diseases. Resveratrol (RSV) is one of those. We will report evidences supporting RSV as a molecule that acts by mimicking the beneficial effects of dietary restriction, and may share common downstream targets with rapamycin and metformin. Although those molecules do not reveal all the secrets of the fountain of youth, they may help us maintaining the quality of life in the old age. © 2010 International Union of Biochemistry and Molecular Biology, Inc.
Waking up to ourselves: The use of mindfulness meditation and emotional intelligence in the teaching of communications
Authors: Huston Dan
Published: September 2010

Communication concepts can be viewed as internal and external influences on our behavior that typically have an unconscious impact on us. Mindfulness meditation can help us become more aware of these influences as they occur moment to moment, allowing us to observe our emotional reactions to them and enabling us to break free of habitual patterns of behavior, thus broadening our communicative options in each moment of our lives.
Contemplative practices in human services education
Authors: Griswold Jacqueline M.
Published: September 2010

This chapter describes ways in which contemplative practices are used in a human services education program to help students integrate self‐care into their lives.
Multivessel peripheral revascularization for acute stroke intervention: Successful M2 bifurcation stenting and the growing case for comprehensive endovascular interventional training
Authors: Badawi Ramy A. , Patel Rajan A.G. , Reilly John P.
Published: September 2010

A comprehensive endovascular skill set is desirable and key to successful intervention in the patient with complex cardiovascular disease. Acute stroke intervention is the next frontier for the endovascular specialist. We report a case of acute stroke intervention in a patient with severe peripheral vascular disease performed by interventional cardiologists with peripheral endovascular skills that clearly demonstrates the new paradigm of global revascularization. © 2010 Wiley‐Liss, Inc.
Percutaneous retrieval of the locked helex septal occluder
Authors: Poommipanit Paul , Levi Daniel , Shenoda Michael , Tobis Jonathan
Published: September 2010

The HELEX device is approved for percutaneous closure of an atrial septal defect (ASD). It is also often used off‐label to close patent foramen ovale (PFO). The device is well tolerated because it is very flexible, but this characteristic increases the likelihood of embolization of locked implants. While the company provides a mechanism to retrieve devices that do not lock correctly, retrieval of locked and released devices is much more difficult. A case of percutaneous retrieval of an embolized, locked HELEX device is reported. This device was successfully retrieved from the aorta by snaring the left atrial eyelet and unlocking the device. A variety of potential techniques for retrieval of these devices was explored on the bench top. Strategies which can be used to successfully retrieve embolized HELEX devices are described. © 2011 Wiley‐Liss, Inc.
ChemInform Abstract: Intermetallic Compounds Formed by Electrodeposition of Indium on Bismuth.
Authors: CANEGALLO S. , DEMENEOPOULOS V. , PERALDO BICELLI L. , SERRAVALLE G.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Benzylation of Achiral Lithium Enolates Using a Chiral Ligand for Lithium in the Presence of an Achiral Ligand.
Authors: IMAI M. , HAGIHARA A. , KAWASAKI H. , MANABE K. , KOGA K.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Synthesis of syn‐α,β‐Epoxy Alcohols by Diastereoselective Carbonyl Reduction of α,β‐Epoxy Ketones.
Authors: KAWAKAMI T. , SHIBATA I. , BABA A. , MATSUDA H. , SONODA N.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Aminolysis of 3‐Hydroxy‐2‐naphthoic Acid.
Authors: KONDRATOV S. A. , SHTEINBERG L. YA. , SHEIN S. M. , UDOVICHENKO L. V. , BOIKO V. D.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of β‐Amino Nitriles and 1,3‐Diamines.
Authors: REETZ M. T. , KAYSER F. , HARMS K.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (Indenyl)cobalt(I)‐Catalyzed Cocyclization of Alkyne, Alkene, and Carbon Monoxide to Cyclopentenones.
Authors: LEE B. Y. , CHUNG Y. K. , JEONG N. , LEE Y. , HWANG S. H.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Autocomplexes of the Picryl Series with One‐Membered O‐Bridges
Authors: IL'INA I. G. , ZABAZNOVA S. V. , IVANOVA E. V. , BUTIN K. P.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A General Synthesis of Chromenes.
Authors: AUKRUST I. R. , NOUSHABADI M. , SKATTEBOEL L.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Pharmacological Investigations of New 6‐Oxo‐1,2,3,4‐ tetrahydro‐6H‐pyrimido(2,1‐b)quinazoline Derivatives.
Authors: KORZYCKA L. , SZADOWSKA A. , PAKULSKA W.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reactions of 3‐Substituted‐4‐amino‐5‐mercapto‐1,2,4‐triazoles with Acetylenic Ketones and α‐Bromochalcones.
Authors: KALLURAYA B. , D'SOUZA A. , HOLLA B. S.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Construction of the 17α‐Fluoroprogesterone Side Chain.
Authors: NEEF G. , AST G. , MICHL G. , SCHWEDE W. , VIERHUFE H.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selective Alkylation of Protected Peptide Derivatives by Phase‐ Transfer Catalysis.
Authors: O'DONNELL M. J. , BURKHOLDER T. P. , KHAU V. V. , ROESKE R. W. , TIAN Z.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Synthesis of γ‐D‐ and ‐L‐Glutamyl‐L‐meso‐ diaminopimelic Acid Dipeptide.
Authors: WILLIAMS R. M. , YUAN C.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Towards the KDO Synthesis. Preparation of 5,6:7,8‐Di‐O‐isopropylidene‐ 5,4‐dideoxy‐D‐manno‐oct‐1,4‐lactone.
Authors: JAROSZ S. , KOZLOWSKA E. , CIUNIK Z.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Petrosin.
Authors: SCOTT R. W. , EPPERSON J. R. , HEATHCOCK C. H.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild and Efficient Methodology for the Synthesis of 5‐Halogeno Uracil Nucleosides that Occurs via a 5‐Halogeno‐6‐azido‐5,6‐dihydro Intermediate.
Authors: KUMAR R. , WIEBE L. I. , KNAUS E. E.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Iodo‐Aryl‐Azido Adenosine Analogues as Affinity Ligands for Adenylyl Cyclase.
Authors: SHOSHANI I. , QIU H. , JOHNSON F. , JOHNSON R. A.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 3′‐Fluoro‐3′‐deoxy‐N6‐cyclopentyladenosine.
Authors: CEULEMANS G. , BUSSON R. , WEYNS N. , VANDENDRIESSCHE F. , ROZENSKI J. , IJZERMAN A. , HERDEWIJN P.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Atropdiastereoselective Total Synthesis of Phleichrome (I) and the Protein Kinase C Inhibitor Calphostin A (II)
Authors: COLEMAN R. S. , GRANT E. B.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Li+ Conducting Ceramics
Authors: AONO H. , IMANAKA N. , ADACHI G.
Published: September 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pressure‐Induced Spin‐State Transition in BiCoO3.
Authors: Oka Kengo , et al. et al.
Published: September 2010

Synchrotron X‐ray and neutron powder diffraction measurements show that the structure of the title compound changes from a polar tetragonal PbTiO3‐type (space group P4mm) to a centrosymmetric orthorhombic GdFeO3‐type (space group Pbnm) above 3 GPa with a large volume decrease of 13% at room temperature revealing a spin‐state change.
ChemInform Abstract: Structural, Transport, and Electrochemical Investigation of Novel AMSO4F (A: Na, Li; M: Fe, Co, Ni, Mn) Metal Fluorosulfates Prepared Using Low Temperature Synthesis Routes.
Authors: Barpanda Prabeer , Chotard Jean‐Noel , Recham Nadir , Delacourt Charles , Ati Mohamed , Dupont Loic , Armand Michel , Tarascon Jean‐Marie
Published: September 2010

The sodium‐based title compounds are synthesized by solid state reaction of MSO4·H2O (M: Fe, Co, Ni, Mn) and a slight excess of NaF (Parr reactor, 300 °C, 40—50 h) and ionothermally from mixtures of the same precursors and [emim][NTf2] (autoclave, 300 °C, 9 h).
ChemInform Abstract: The Thioantimonate Anion [Sb4S8]4‐ Acting as a Tetradentate Ligand: Solvothermal Synthesis, Crystal Structure and Properties of {[In(C6H14N2)2] 2Sb4S8}Cl2 Exhibiting Unusual Uniaxial Negative and Biaxial Positive Thermal Expansion.
Authors: Quiroga‐Gonzalez Enrique , Naether Christian , Bensch Wolfgang
Published: September 2010

Title compound (III) crystallizes in the monoclinic space group C2/c with Z = 4 (single crystal XRD).
ChemInform Abstract: A Layered Titanium Phosphate Ti2O3 (H2PO4)2·2H2O with Rectangular Morphology: Synthesis, Structure, and Cysteamine Intercalation.
Authors: Koroesi Laszlo , Papp Szilvia , Dekany Imre
Published: September 2010

The layered title compound is prepared from a mixture of Ti(OiPr)4, H3PO4, and 2‐propanol and characterized by XRD, SEM, and TEM.
ChemInform Abstract: Two Distinct Manganese Molybdenum(V) Phosphates Directed by Different Organic Amines.
Authors: Zhu Min , Peng Jun , Tian Ai‐Xiang , Pang Hai‐Jun , Zhang Peng‐Peng , Chen Yuan , Wang Dan‐Dan , Wang Yong‐Hui
Published: September 2010

The structures of the new polyoxomolybdatophosphates (IV) (monoclinic, space group P21/n, Z = 2) and (V) (monoclinic, C2/c, Z = 4) are determined by single crystal XRD.
ChemInform Abstract: Chiral Tetrafluorobenzobarrelenes as Effective Ligands for Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Arylboroxines to β,β‐Disubstituted α,β‐Unsaturated Ketones.
Authors: Shintani Ryo , Takeda Momotaro , Nishimura Takahiro , Hayashi Tamio
Published: September 2010

A novel Rh catalyst is presented for the highly stereoselective addition of arylboroxines (II) towards α,β‐unsaturated ketones, giving ketones bearing a quaternary β‐stereocenter with excellent enantioselectivity (up to 99% e.e.).
ChemInform Abstract: The First Pincer‐Type Phosphodiamidite Ligand Containing Chiral Phosphorus Atoms.
Authors: Gavrilov K. N. , Rastorguev E. A. , Shiryaev A. A. , Grishina T. B. , Safronov A. S. , Lyubimov S. E. , Davankov V. A.
Published: September 2010

The first pincer‐type phosphodiamidite ligand is synthesized and applied as catalyst ligand in the Pd‐catalyzed enantioselective allylic sulfonylation of ester and carbonate (I) and in the Pd‐catalyzed deracemization of compound (Ib).
ChemInform Abstract: Synthesis and Bioassay of Pyrrolyl Oxazolines and Thiazolines.
Authors: Padmavathi V. , Mahesh K. , Reddy G. Dinneswara , Padmaja A.
Published: September 2010

Exploiting lanthanide chemistry and 1,3‐dipolar cycloaddition technology, title compounds (V) are prepared as a new class of substituted pyrroles.
ChemInform Abstract: Heterocyclization of Hydrazine with Acetaldehyde and H2S.
Authors: Akhmetova V. R. , Nadyrgulova G. R. , Murzakova N. N. , Starikova Z. A. , Antipin M. Yu. , Kunakova R. V.
Published: September 2010

3,7‐Dithia‐1,5‐diazabicyclooctane (II) is obtained by regioselective condensation of hydrazine with a mixture of acetaldehyde and H2S.
ChemInform Abstract: Stereoselective Additions of Thiyl Radicals to Terminal Ynamides.
Authors: Banerjee Biplab , Litvinov Dmitry N. , Kang Junghoon , Bettale Jennifer D. , Castle Steven L.
Published: September 2010

Ynamides (I) give under two complementary sets of reaction conditions either (Z)‐ or (E)‐β‐thioenamides by reaction with thiols.
ChemInform Abstract: FeCl3‐Catalyzed Oxidative Allylation of sp2 and sp3 C—H Bond Adjacent to a Nitrogen Atom: Easy Access to Homoallyl Tertiary Amines.
Authors: Kumaraswamy Gullapalli , Murthy Akula Narayana , Pitchaiah Arigala
Published: September 2010

Surprisingly, reaction of the anisidines (XII) does not give the expected α‐allylated products but ortho‐allylated derivatives (XIII).
ChemInform Abstract: Synthesis of α,β‐Unsaturated Caprolactams Starting from Heterocyclic Imines.
Authors: Johannes Katharina , Watzke Martin , Martens Juergen
Published: September 2010

Addition of unsaturated acid chlorides (II) to heterocyclic imines (I) followed by reaction with unsaturated nucleophiles (III), (VI), (IX) and subsequent ring closing metathesis afford the α,β‐unsaturated caprolactams (V), (VIII) and (XI), containing, sulfur, nitrogen, or selenium atoms in the δ‐position.
ChemInform Abstract: Iron‐Catalyzed Cross‐Coupling Between 1‐Bromoalkynes and Grignard‐Derived Organocuprate Reagents.
Authors: Castagnolo Daniele , Botta Maurizio
Published: September 2010

The use of in situ generated organocopper instead of simple Grignard reagents is the key factor to suppress undesirable side homocoupling and to lead the reaction to completion.
ChemInform Abstract: Heterogeneously Catalyzed Oxidative Cyanation of Tertiary Amines with Sodium Cyanide/Hydrogen Peroxide Using Polymer‐Supported Iron (II) Phthalocyanines as Catalyst.
Authors: Singhal Sweety , Jain Suman L. , Sain Bir
Published: September 2010

The catalyst can be easily recovered and reused for at least five times without any loss of activity and metal leaching.
ChemInform Abstract: Highly Enantioselective Conjugate Addition of Thioglycolate to Chalcones Catalyzed by Lanthanum: Low Catalyst Loading and Remarkable Chiral Amplification.
Authors: Hui Yonghai , Jiang Jun , Wang Wentao , Chen Weiliang , Cai Yunfei , Lin Lili , Liu Xiaohua , Feng Xiaoming
Published: September 2010

A remarkably strong positive nonlinear effect is observed using ligand (I) with only 2% enantiomeric excess.
ChemInform Abstract: Magnesium Metal Mediated Reductive Trifluoromethylation of Aldehydes with Phenyl Trifluoromethyl Sulfone.
Authors: Zhao Yanchuan , Zhu Jieming , Ni Chuanfa , Hu Jinbo
Published: September 2010

The method is suitable for enolizable and non‐enolizable aldehydes via formation of a CF3‐ species.
ChemInform Abstract: Reaction of 3‐Chloro‐1‐(2,4,6‐trimethylphenyl)propan‐2‐one with Amines.
Authors: Yadigarov R. R. , Khalilov A. N. , Mamedov I. G. , Nagiev F. N. , Magerramov A. M. , Allakhverdiev M. A.
Published: September 2010

The reaction of the title α‐chloro ketone (II) with primary amines is unexpectedly accompanied by a Favorskii rearrangement furnishing the amides (IV) (7 examples).
ChemInform Abstract: Microwave‐Promoted, One‐Pot Conversion of Alkoxymethylated Protected Alcohols into Their Corresponding Nitriles, Bromides, and Iodides Using [bmim][InCl4] as a Green Catalyst.
Authors: Mirjafari Arsalan , Mohammadpoor‐Baltork Iraj , Moghadam Majid , Tangestaninejad Shahram , Mirkhani Valiollah , Khosropour Ahmad Reza
Published: September 2010

Direct transformation of benzylic and aliphatic Mom and Eom ethers is achieved with the corresponding tetrabutylammonium salts.
ChemInform Abstract: An Efficient and Reusable PdCl2/TBAF System for the Heck Reaction under Ligand‐ and Solvent‐Free Conditions.
Authors: Tao Li‐Ming , Li Qiang‐Guo , Liu Wen‐Qi , Zhou Yun , Zhou Ju‐Feng
Published: September 2010

The Heck cross‐coupling reaction between aryl halides and alkenes is improved by PdCl2 combined with Bu4NF (TBAF) under solvent‐free conditions.
ChemInform Abstract: Highly Enantioselective Aza‐Ene‐Type Reaction Catalyzed by Chiral N,N′‐Dioxide‐Nickel(II) Complex.
Authors: Zheng Ke , Liu Xiaohua , Zhao Jiannan , Yang Yang , Lin Lili , Feng Xiaoming
Published: September 2010

The highly enantioselective aza‐ene‐type reaction of glyoxal derivatives (I) with enamides (X) and enecarbamates (II) and (VI) is realized using a chiral Ni‐complex as the catalyst.
ChemInform Abstract: Endoxifen is a New Potent Inhibitor of PKC: A Potential Therapeutic Agent for Bipolar Disorder.
Authors: Ali Shoukath M. , Ahmad Ateeq , Shahabuddin Syed , Ahmad Moghis U. , Sheikh Saifuddin , Ahmad Imran
Published: September 2010

Endoxifen (VII), a tamoxifen active metabolite, is synthesized starting from commercially available materials.
ChemInform Abstract: Synthesis of New 2‐Substituted 2,5‐Dihydrofuranone Derivatives and Their Chemical Transformations.
Authors: Avetisyan A. A. , Alvandzhyan A. G. , Avetisyan K. S.
Published: September 2010

Tertiary α‐hydroxyketones react with malononitrile to give dihydrofuran‐2‐imines along with products of their subsequent reaction with a second malononitrile molecule.
ChemInform Abstract: Synthesis and Anticancer Activity of Some Novel 2‐Substituted Benzimidazole Derivatives.
Authors: Refaat Hanan M.
Published: September 2010

Several of the synthesized compounds are subjected to in vitro anticancer screening (cell lines HEPG2, MCF7, HCT 116).
ChemInform Abstract: Reduction of 7‐Aryl‐6,8‐dioxo‐2‐oxa‐3,7‐diazabicyclo[3.3.0]oct‐3‐ene‐4‐carboxylic and 7‐Aryl‐6,8‐dioxo‐1‐oxa‐2,7‐diazaspiro[4.4]non‐2‐ene‐3‐carboxylic Acid Esters.
Authors: Stepakov A. V. , Galkin I. A. , Larina A. G. , Molchanov A. P. , Kostikov R. R.
Published: September 2010

The reduction of the title compound with NaBH4 occurs selectivity at the carbonyl group in the carbonyl group in the β‐position with respect to the oxygen atom in the isoxazole ring.
ChemInform Abstract: Synthesis of 1,2,4‐Triazole‐3‐thiols and Their S‐Substituted Derivatives.
Authors: Kochikyan T. V. , Samvelyan M. A. , Arutyunyan V. S , Avetisyan A. A. , Tamazyan R. A. , Aivazyan A. G.
Published: September 2010

New triazolethiols (IV) are synthesized via alkali‐mediated cyclization of 1,4‐disubstituted thiosemicarbazides (III).
ChemInform Abstract: Synthesis, Characterization and Thermal Behaviors of 4‐Amino‐5‐nitro‐1,2,3‐triazole (ANTZ) and Its Derivatives.
Authors: Wang Bozhou , Li Jizhen , Huo Huan , Fan Xuezhong , Fu Xiaolong , Zhou Cheng
Published: September 2010

The synthesis of 4‐amino‐5‐nitro‐1,2,3‐triazole (II), a high performance insensitive explosive, via Hofmann rearrangement and its transformation into a high nitrogen containing derivative (IV) or salt (VI) are reported.
ChemInform Abstract: Polyketide Assembly by Alkene—Alkyne Reductive Cross‐Coupling: Spiroketals Through the Union of Homoallylic Alcohols.
Authors: Canterbury Daniel P. , Micalizio Glenn C.
Published: September 2010

A reaction sequence involving regioselective formal hydroalkynylation, reductive ene‐yne cross‐coupling, and oxidative cyclization is developed to prepare stereochemically dense spiroketals following similar pathways.
ChemInform Abstract: Novel 3‐Alkanoyl/Aroyl/Heteroaroyl‐2H‐chromene‐2‐thiones: Synthesis and Evaluation of Their Antioxidant Activities.
Authors: Singh Okram Mukherjee , Devi Nepram Sushuma , Thokchom Dhanaraj Singh , Sharma Gurumayum Jitendra
Published: September 2010

A combinatorial library of title chromenethiones is synthesized by condensation of β‐oxodithioesters (I) with aromatic aldehydes (II) under solvent‐free conditions.
ChemInform Abstract: One‐Step Synthesis of Hantzsch Esters and Polyhydroquinoline Derivatives Using New Organocatalyst.
Authors: Baghbanian Seyed Meysam , Khaksar Samad , Vahdat Seyed Mohammad , Farhang Maryam , Tajbakhsh Mahmood
Published: September 2010

Guanidine hydrochloride is highly efficient for the synthesis of esters (III) and (V).