bluuebunny/crossref_metadata_2025 huggingface dataset:
A NEW DECISION MODEL FOR CROSS-DOCKING CENTER LOCATION IN LOGISTICS NETWORKS UNDER INTERVAL-VALUED INTUITIONISTIC FUZZY UNCERTAINTY
Authors: Meysam Mousavi Seyed , Antuchevičienė Jurgita , Zavadskas Edmundas Kazimieras , Vahdani Behnam , Hashemi Hassan
Published: January 2019

Cross-dock has been a novel logistic approach to effectively consolidate and distribute multiple products in logistics networks. Location selection of cross-docking centers is a decision problem under different conflicting criteria. The decision has a vital part in the strategic design of distribution networks in logistics management. Conventional methods for the location selection of cross-docking centers are insufficient for handling uncertainties in Decision-Makers (DMs) or experts’ opinions. This study presents a modern Multi-Criteria Group Decision-Making (MCGDM) model, which applies the concept of compromise solution under uncertainty. To address uncertainty, Interval-Valued Intuitionistic Fuzzy (IVIF) sets are used. In this paper, first an IVIF-weighted arithmetic averaging (IVIF-WAA) operator is used in order to aggregate all IVIF-decision matrices, which were made by a team of the DMs into final IVIF-decision matrix. Then, a new Collective Index (CI) is developed that simultaneously regards distances of cross-docking centers as candidates from the IVIF-ideal points. Finally, the feasibility and practicability of proposed MCGDM model is illustrated with an application example on location choices of cross-docking centers to the logistics network design.
Asymmetric Drift in the Andromeda Galaxy (M31) as a Function of Stellar Age
Authors: Quirk Amanda , Guhathakurta Puragra , Chemin Laurent , Dorman Claire E. , Gilbert Karoline M. , Seth Anil C. , Williams Benjamin F. , Dalcanton Julianne J.
Published: January 2019

We analyze the kinematics of Andromeda’s disk as a function of stellar age by using photometry from the Panchromatic Hubble Andromeda Treasury survey and spectroscopy from the Spectroscopic and Photometric Landscape of Andromeda’s Stellar Halo survey. We use H i 21 cm and CO (

) data to examine the difference between the deprojected rotation velocity of the gas and that of the stars. We divide the stars into four stellar age bins, from shortest lived to longest lived: massive main-sequence stars (0.03 Gyr), more luminous intermediate-mass asymptotic giant branch (AGB) stars (0.4 Gyr), less luminous intermediate-mass AGB stars (2 Gyr), and low-mass red giant branch stars (4 Gyr). There is a clear correlation between the offset of the stellar and the gas rotation velocity, or the asymmetric drift: the longer-lived populations lag farther behind the gas than short-lived populations. We also examine possible causes of the substructure in the rotation curves (RCs) and find that the most significant cause of scatter in the RCs comes from the tilted ring model being an imperfect way to account for the multiple warps in Andromeda’s disk.
Energy Transport and Heating by Torsional Alfvén Waves Propagating from the Photosphere to the Corona in the Quiet Sun
Authors: Soler Roberto , Terradas Jaume , Oliver Ramón , Ballester José Luis
Published: January 2019

In the solar atmosphere, Alfvén waves are believed to play an important role in the transfer of energy from the photosphere to the corona and solar wind, and in the heating of the chromosphere. We perform numerical computations to investigate the energy transport and dissipation associated with torsional Alfvén waves propagating in magnetic flux tubes that expand from the photosphere to the corona in quiet-Sun conditions. We place a broadband driver at the photosphere that injects a wave energy flux of 107 erg cm−2 s−1 and consider Ohm’s magnetic diffusion and ion–neutral collisions as dissipation mechanisms. We find that only a small fraction of the driven flux, ∼105 erg cm−2 s−1, is able to reach coronal heights, but it may be sufficient to partly compensate the total coronal energy loss. The frequency of maximal transmittance is ∼5 mHz for a photospheric field strength of 1 kG and is shifted to smaller/larger frequencies for weaker/stronger fields. Lower frequencies are reflected at the transition region, while higher frequencies are dissipated, producing enough heat to balance chromospheric radiative losses. Heating in the low and middle chromosphere is due to Ohmic dissipation, while ion–neutral friction dominates in the high chromosphere. Ohmic diffusion is enhanced by phase mixing because of the expansion of the magnetic field. This effect has the important consequence of increasing the chromospheric dissipation and, therefore, reducing the energy flux that reaches the corona. We provide empirical fits of the transmission coefficient that could be used as input for coronal models.
Cassini Ring Seismology as a Probe of Saturn’s Interior. I. Rigid Rotation
Authors: Mankovich Christopher , Marley Mark S. , Fortney Jonathan J. , Movshovitz Naor
Published: January 2019

Seismology of the gas giants holds the potential to resolve long-standing questions about their internal structure and rotation state. We construct a family of Saturn interior models constrained by the gravity field and compute their adiabatic mode eigenfrequencies and corresponding Lindblad and vertical resonances in Saturn’s C ring, where more than 20 waves with pattern speeds faster than the ring mean motion have been detected and characterized using high-resolution Cassini Visual and Infrared Mapping Spectrometer stellar occultation data. We present identifications of the fundamental modes of Saturn that appear to be the origin of these observed ring waves, and we use their observed pattern speeds and azimuthal wavenumbers to estimate the bulk rotation period of Saturn’s interior to be

(median and 5%/95% quantiles), significantly faster than Voyager and Cassini measurements of periods in Saturn’s kilometric radiation, the traditional proxy for Saturn’s bulk rotation period. The global fit does not exhibit any clear systematics indicating strong differential rotation in Saturn’s outer envelope.
Finite Element Approach of Interior Permanent Magnet Motor Acoustics Noise
Authors: Vyroubal P. , Maxa J. , Kazda T. , Mačák M.
Published: January 2019

IPM (Interior Permanent Magnet) motors produce torque based on two different mechanisms. The first of them is permanent-magnet torque, which is generated by the flux linkage between the PM (Permanent Magnet) rotor field and the electro-magnetic field of the stator. It is the same torque as produced by SPM (Surface Permanent Magnet) motors, however, IPM designs produce another force known as reluctance torque. The second one, the shape and location of the slots in the rotor laminations are designed to channel magnetic flux so that even if the slots were left as air gaps, the rotor would experience a force to align the magnetic flux lines with those generated by the stator coils. IPM motors are now very popular in industrial and military applications by providing high power density and high efficiency compared to other types of motors. This paper presents the use of finite element method harmonic analysis for investigation of IPM motor acoustics noise. This method is useful for DC (Direct Current) motor designs in many industrial and military applications.
Novel Tactical Ballistic Shield Technology: A Blast Injury Mitigation Evaluation
Authors: Desmoulin G. T. , Nolette M. -A.
Published: January 2019

This study investigates the performance of a shield appliqué technology designed to protect the user from blast injury. This technology was compared against three other ballistic shields of varying mass using a fixed charge configuration. An instrumented anthropomorphic test dummy (ATD) was used along with pressure sensors to determine injury risk. Results showed that lighter shields offered less protection than their heavier counterparts with higher probability of head, chest, arm and leg injuries. Additionally, when comparing the appliqué to a mass-matched shield, relevant loadings were reduced on average by 21 %. Overall, the ballistic shield appliqué technology shows promise for becoming a tool for blast mitigation in the short to medium term.
Ballistics of Supercavitating Projectiles
Authors: Thai D. , Horák V. , Van D. , Van D. , Van H. , Duc L.
Published: January 2019

The article is focused on the development of the underwater ballistic model of a supercavitating projectile fired from an underwater firearm. The supercavitating flows and their influences on the ballistic characteristics of the projectile are studied. The presented mathematical model is validated and experimentally verified for the supercavitating projectile of 5.7 mm in diameter fired from a smooth bore underwater rifle.
Taxonomic reconsideration of Prunus veitchii (Rosaceae)
Authors: Wu Baohuan , Liu Chaoyu , Potter Daniel , Cui Dafang
Published: January 2019

Prunusveitchii was published in 1912 and was treated as a synonym of P.serrulatavar.pubescens. The information about this taxon is relatively scarce. When consulting specimens of Prunus L., type materials of Prunusveitchii were found to belong to three taxa and P.veitchii, P.concinna, P.japonicavar.zhejiangensis, C.jingningensis and C.xueluoensis were found to be conspecific. The taxonomic status of P.veitchii is reconsidered in the present paper. Morphometric analyses were performed to evaluate the significance of differences between P.veitchii and P.serrulatavar.pubescens. The results show that the leaves of P.veitchii are significantly smaller and narrower than the leaves of P.serrulatavar.pubescens and the peduncle and pedicels are shorter. According to the results of morphometric analyses, P.veitchii should be treated as a separate species. To address these results, a lectotype of P.veitchii is designated here and P.concinna, Cerasusjingningensis and C.xueluoensis are here designated as synonyms of P.veitchii.
Do PD-1 and PD-L2 expression have prognostic impact in hematologic malignancies?
Authors: KORKMAZ SERDAL , ERDEM SELAHATTİN , AKAY EBRU , TAŞDEMİR ERDEM ARZU , KARAMAN HATİCE , KEKLİK MUZAFFER
Published: January 2019

Background and Aim: PD-1 (programmed death-1) is an immune checkpoint receptor that modulates T-cell activity in peripheral tissues via interaction with its ligands, PD-L1 (programmed death-ligand 1) and PD-L2 (programmed death-ligand 2). Tumor cells upregulate PD-L1 or PD-L2 to dampen this T lymphocyte attack. Our goal was to demostrate the PD-1 and PD-L2 expresion rate of various hematologic malignancies, and to evaluate whether PD-1 and PD-L2 expresion have impact on prognosis.
Materials and Methods: For this purpose, pre-treatment bone marrow biopsy specimens of 83 patients [42 multiple myeloma (MM), 21 acute leukemias, and 20 chronic lymphocytic leukemia (CLL)] have been stained with monoclonal antibody immunstains of PD-1 and PD-L2.
Results: As a result, the overall expression rate of PD-1 was 26.2%, 4.8%, and 60% in patients with MM, acute leukemias, and CLL, respectively. Whereas, PD-L2 expression rate was 61.9%, 14.3%, and 10% in patients with MM, acute leukemias, and CLL, respectively.
Conclusion: Finally, we conclude that the role of PD-1 pathway can be demonstrated by immunohistochemistry (IHC). Since we have evaluated whether there is a correlation between (IHC) results and survival of patients with MM, acute leukemias, and CLL, we couldn’t demonstrate a meaningful evidence that these markers have an impact on prognosis.
Key Words: PD-1, PD-L2, multiple myeloma, acute leukemias, chronic lymphocytic leukemia.
Ischemic modified albumin as a new biomarker in predicting of oxidative stress in alopecia areata
Authors: ATAŞ HATİCE , GÖNÜL MÜZEYYEN , ÖZTÜRK YASİN , KAVUTÇU MUSTAFA
Published: January 2019

Background and aim: The results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA), other markers of the oxidant/antioxidant system; such as SOD, CAT, GSH-ST and MDA, and contributing clinical risk factors.
Materials and Methods: The usefulness of IMA as a new marker for oxidative stress was compared with other markers, and evaluated in patients with AA.
Results: The mean serum level of IMA was of higher statistical significance in AA patients than in the control group (IMA: 0.57±0.01 vs. 0.52±0.02 ΔABSU, p<0.0001). IMA (p=0.03, OR=25.8, 95% CI=1.4–482.7) was found to be an independent predictor of oxidative stress in patients with AA. Increased severity of AA was found as an independent risk factor for IMA.
Conclusion: Long-lasting disease, male gender, >1 site involvement of disease and increased severity of disease were correlated with increased oxidation. Presence of AA, male gender and severe disease were determined to be independent risk factors for antioxidant and oxidant systems. IMA has great potential as a biomarker of oxidative stress in AA when compared to other studied biomarkers.
Keywords: biomarkers, alopecia areata, oxidative stress, antioxidative system, ischemia-modified albumin
Association of common IL-10 promoter gene variants with the susceptibility to head and neck cancer in Tunisia
Authors: MAKNI LAMIA , BEN HAMDA CHERIF , AL ANSARI ABRAR , SOUAIAI OUSSEMA , GAZOUANI EZZEDINE , MEZLINI AMEL , Y ALMAWI WASSIM , YACOUBI-LOUESLATI BESMA
Published: January 2019

Background/aim : We investigated the association of three IL-10 promoter single-nucleotide polymorphisms and altered IL-10 plasma levels with the risk of head and neck cancer (HNC).
Material and methods : Study subjects comprised 194 HNC patients [137 nasopharyngeal cancer (NPC) and 57 laryngeal cancer (LC)], and 263 healthy controls. Genotyping of rs1800896 (-1082A>G), rs1800871 (-819C>T), and rs1800872 (-592A>C) IL-10 variants was performed by real-time PCR; IL-10 levels were measured by Enzyme Amplified Immuno Sensitivity Assay (EAISA).
Results : Carriage of rs1800896 A/A genotype was more frequent in HNC and NPC cases, but was less frequent in controls than LC patients. Significant differences in IL-10 levels was seen between rs1800896A/G genotype-carrying NPC cases and controls. Positive association with NPC and LC was seen for rs1800871C/C, and carriage of rs1800872A/A genotype and A allele were associated with higher risk of HNC and NPC, but not LC. GT rs1800896-rs1800871 haplotype was more frequent among HNC and NPC cases than controls, in contrast to GC haplotype, which has a protective effect. Positive association was found between TA haplotype and LC.
Conclusion : Our results demonstrate that IL-10-1082, IL-10-819 and IL-10-592 variants, and haplotypes GC and GT constitute biomarkers for early detection of HNC, especially NPC subtype. IL-10 -819T/C and TA haplotype may be used as biomarkers for early detection of LC.
Keywords: Head and neck cancer, Interleukin-10, laryngeal cancer, nasopharyngeal cancer, Tunisia
Comparison of conventional and modern methods in determining ischemic stroke etiology by general and stroke neurologists
Authors: KUNT REFİK , KUTLUK MUSTAFA KÜRŞAD , TİFTİKÇİOĞLU BEDİLE İREM , AFŞAR FAK NAZİRE EFSER YEŞİM , ERDEMOĞLU ALİ KEMAL , GEDİZLİOĞLU MUHTEŞEM , ÖZTÜRK VESİLE
Published: January 2019

Background/aim: To investigate the consistency between stroke and general neurologists in subtype assignment using Trial of ORG-10172 using Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems.
Materials and methods: Fifty consecutive, acute ischemic stroke patients admitted to Stroke Unit were recruited. Patients were classified two stroke and two general neurologists, each from different medical centers, according to TOAST followed by CCS. Each neurologist was assessed for consistency and compliance in pairs. Concordance among all four neurologists was investigated and evaluated using Kappa(ĸ)-value.
Results: Kappa(ĸ)-value of diagnostic compliance between stroke neurologists was 0.61 (95%CI 0.45-0.77) for TOAST and 0.78 (95%CI 0.62-0.94) for CSS-5. Kappa(ĸ)-value was 0.64 (95%CI 0.48–0.80) for TOAST and 0.75 (95%CI 0.60–0.91) for CCS-5 for general neurologists. Compliance was moderate [ĸ:0.59 (95%CI 0.52–0.65)] in TOAST and was strong [ĸ:0.75 (95%CI 0.68–0.81)] in CCS-5 for all 4 neurologists. ‘Cardioembolism’(91.04%) has reached the highest compliance in both systems. The frequency of group with ‘undetermined etiologies’ was less in CCS (26%) compared to TOAST.
Conclusions: The CCS system improved the compliance in both stroke and general neurologists compared with TOAST. These suggest that automatic, evidence-based, easily reproducible CCS system was superior to TOAST system.
Keywords: TOAST, CCS, Ischemic stroke, Etiology
The effect of isotretinoin on insulin resistance and adipocytokine levels in acne vulgaris patients
Authors: SOYUDURU GONCA , ÖZSOY ADIŞEN ESRA , KADIOĞLU ÖZER İLKAY , AKSAKAL AHMET BURHAN
Published: January 2019

Background and Aim: Recent data draw attention to the effect of body composition, insulin resistance and adipocytokines to acne vulgaris (AV) development. The aim of this study to assess the association of AV with insulin resistance and adipocytokine levels and to evaluate the effect of isotretinoin on insulin resistance and adipocytokine levels.
Material and Methods: In 29 AV patients and 29 healthy volunteers, body mass index (BMI) and body fat mass (BFM), lipid, adiponectin, leptin, resistin, retinol binding protein-4 (RBP4) and insulin levels were measured and insulin resistance was assessed by HOMA-IR index in serum samples taken twice from patients before and after isotretinoin treatment.
Results: In AV patients, pretreatment HOMA-IR and adipocytokine level was not found to correlate with disease severity. With five months of isotretinoin treatment, higher HOMA-IR values were found (p=0.028). Isotretinoin therapy maintained lower mean resistin levels (p = 0.016), higher mean RBP4 levels (p = 0.040), but not affected the mean adiponectin and leptin levels (p = 0.113, p = 0.125, respectively).
Conclusions: All data suggests that five months of isotretinoin therapy in AV patients causes insulin resistance and the increase in insulin resistance is not dependent on age, BMI, BFM and lipid levels of these patients.
Key words: Acne vulgaris, adipocytokine, insulin sensitivity
A comparative biomechanical analysis of suprapectineal and infrapectineal fixation on acetabular anterior column fracture by finite element modeling
Authors: YÜCENS MEHMET , ALEMDAROĞLU KADİR BAHADIR , ÖZMERİÇ AHMET , İLTAR SERKAN , YILDIRIM AHMET ÖZGÜR , HÜRRİYET AYDOĞAN NEVRES
Published: January 2019

Background: The aim of this study is to compare the stability and implant stresses of suprapectineal plate with infrapectineal plate in three subconfigurations of the screw types.
Methods: The stabilities of different fixation methods were compared by finite-element analysis on six models. Three infrapectineal models and three suprapectineal models each with locked, unlocked or combined screws were employed. Three-dimensional finite element stress analysis was performed by using isotropic materials with a load of 2.3 kN applied at standing positions. Motion at the fracture line was measured on four different points that are located at pubic and iliac side of the fracture line.
Results: Infrapectineal plate fixation with unlocked screws was found to be the most stable fixation method with 0.006 mm displacement of fragments in all axes at standing positions. Suprapectineal unlocked method was found to be the most unstable in standing positions with maximum distraction values of 0.46 mm vertical shear movement in x-axis, -0.14 mm distraction in y-axis and -0.33 mm lateral shear in z-axis.
Conclusions: To our results infrapectineal unlocked plate supplies the most stable fixation with least implant stress in contrary to the suprapectineal unlocked plate, which has the lowest stability and highest implant stresses.

Keywords: Acetabular fracture; anterior column; suprapectineal; infrapectineal; fixation; finite element.
The role of IFIH1 gene rs1990760 and rs2111485 single-nucleotide polymorphisms in generalized vitiligo predisposition
Authors: ONAN DURU , YORULMAZ AHU , EZGÜ FATİH SÜHEYL , HAYRAN KADİR MUTLU , KÜLCÜ ÇAKMAK SERAY , ARTÜZ REFİKA FERDA , YALÇIN BAŞAK
Published: January 2019

Background and Aim: Interferon-induced helicase (IFIH1) is a gene locus that has been recently defined as a candidate for susceptibility to generalized vitiligo (GV). The objectives of this study were to assess the association of IFIH1 gene, rs2111485 and rs1990760 single-nucleotide polymorphisms (SNP) with susceptibility to GV and the autoimmune diseases accompanying to GV.
Materials and Methods: We prospectively studied GV patients and frequency-matched healthy controls by age and gender. The genotypes of the participants were determined for rs1990760 and rs2111485 SNPs of IFIH1. Dominant, recessive and additive models were evaluated for each SNP adjusted for age and gender.
Results: The patients and their controls were demonstrated to be in the Hardy-Weinberg equilibrium for SNP1 (2q24.2, rs1990760, IFIH1, T/C) and SNP2 (2q24.2, rs2111485, IFIH1, G/A) respectively (all p> 0.7). For SNP1 every T allel addition was significantly associated with 1.53 times protectiveness in terms of vitiligo risk (P= 0.033). As for SNP2 every G allel addition was associated with 1.42 times protectiveness, close to statistical significance (P= 0.100).
Conclusions: We detected that for SNP1 each T allel and for SNP2 each G allel are protective in terms of vitiligo development. Hereby, we confirmed that IFIH1 gene locus has a role in GV susceptibility.
Keywords: Vitiligo, single nucleotide polymorphism, genes
Être différent. Comment accompagner les indifférents
Authors: Meynier Olivier
Published: January 2019

Les émotions vont et viennent se succédant ou s’entrechoquant : je me suis souvent senti incompris, asphyxié et en manque total de reconnaissance sans doute tel le papillon en gestation enfermé dans un cocon sombre et étroit, invisible, échappant aux regards… Quand l’explosion s’est produite, je suis sorti de la chrysalide et là, j’ai affronté les regards fuyants, moqueurs ou insistants… Mais j’ai réussi à sortir mes cartes et je me suis posé tranquillement sur un trèfle à quatre feuilles… Une dame de coeur m’a accueilli dans la paume de sa main, le regard doux et libérateur… J’ai ainsi arrêté de me cogner les ailes dans les coins du quatre de carreau et de me piquer les pattes sur les cactus. Maintenant je perçois ma différence d’être, papillon certes un peu écorché, mais bien vivant et affirmant mon envol même aux yeux des indifférents…
Sarabandes et virevoltes au « Gang Minute Papillon »
Authors: Juteau Anne , Guénoun Tamara , Latoch Marie , Abarcca Carolina , Minute Papillon CATTP
Published: January 2019

Cet article vise à rendre compte collectivement de la singularité de ce travailà plusieurs, initié depuis un an au sein du cattp Minute Papillon. Les auteursprésentent au fil du texte les contours du projet de soin, orienté vers les prisesen charge sensori-motrices, artistiques et culturelles des enfants tsa, au seind’une équipe sanitaire pluridisciplinaire. Après avoir évoqué les références ayant inspiré ce cattp « ludique multi-lubique », une vignette clinique est exposéepour rendre palpable la complexité des parcours de soins des enfants accueilliset la nécessité, alors, de créer des dispositifs de soin à même de naviguer ausein de cette complexité pour y réintroduire du jeu et des capacités de liaisons psychiques, mises à mal par l’intensité des troubles de ces enfants. Pour finir, les auteurs donnent l’exemple du projet de danse, avec les perspectives qu’il ouvresur un travail à plusieurs, pluridisciplinaire, créatif avec les familles d’enfants tsa et ted .
Dépister le risque d’autisme chez les bébés de quelques mois pourrait-il permettre de transformer le pronostic ? La grille preaut , son origine et ses applications
Authors: Laznik Marie-Christine , Saint-Georges Catherine
Published: January 2019

Depuis peu les chercheurs internationaux s’intéressent à la possibilité de détecter l’autisme le plus tôt possible, avant 1 an, en espérant intervenir beaucoup plus efficacement, voire peut-être empêcher l’installation de l’autisme. C’est ce même projet qui est à l’origine de la recherche preaut , imaginée il y a plus de vingt ans par des psychanalystes cliniciens de l’autisme. Les résultats remarquables qui viennent d’être publiés montrent qu’un dépistage ultra-précoce est possible, ouvrant la voie à la possibilité d’une intervention qui pourrait radicalement modifier le devenir de ces bébés.
De la clinique du bébé à l’évaluation du traitement : micro-analyse d’une cohorte, entre psychanalyse et transdisciplinarité
Authors: Parlato de Oliveira Erika , Saint-Georges Catherine
Published: January 2019

Intervenir le plus tôt possible, dès la première année de vie, apparaît aujourd’hui crucial pour espérer modifier la trajectoire développementale et bouleverser le pronostic. Notre recherche a pour objectif d’évaluer les effets d’une intervention utilisant l’approche psychanalytique, en dialogue avec les autres champs du savoir, pour les bébés à risque d’autisme et leurs parents.
Troubles du spectre de l’autisme et simulation : un outil au service du soin
Authors: Descrettes Victoria , Boissel Laure , Vasselin Ingrid , Jalmaut Béatrice , Malpart Aurore , Gignon Maxime , Mille Christian , Ammirati Christine
Published: January 2019

La réalisation d’un examen paraclinique, en milieu hospitalier, pour un enfant ou un adulte atteint de Trouble du spectre de l’autisme ( tsa ) est souvent complexe. Suite à une demande venant des professionnels aux côtés des patients autistes, le centre Simu-Santé, lieu de formation et de simulation destinés aux professionnels de santé, a mis en place des séances de simulation à destination de ces patients. Les séances ont été organisées autour d’un examen que les patients devaient réaliser ( irm de contrôle, radiographie, etc.). Les mises en situation réelles, dans des conditions répétées, ont pour but d’aider les patients à se familiariser avec le déroulement de l’examen, dans des conditions les plus favorables possible afin de permettre la réalisation de l’examen redouté. L’objectif de cet article est de présenter les origines de ce projet ainsi que les bénéfices observés depuis sa mise en place.
Contestation et engagements adolescents
Authors: Nassikas Kostas
Published: January 2019

L’auteur étudie ici les croisements entre la contestation, cette dimension fondamentale dans le processus de séparation-autonomisation adolescent, et l’engagement. Quand celui-ci recouvre l’angoisse de séparation, que contient la contestation, il pousse celle-ci vers les voies de la désocialisation et même de la radicalisation. Quand, au contraire, l’engagement investit des « objets internes », il peut contribuer à la réalisation des buts sociaux et sublimés.
Nurses' Positive Experiences in Caring for Older Adults With Dementia: A Qualitative Analysis
Authors: Choi Yun-Jung , Choi Hwa-Bok
Published: January 2019

A qualitative study was conducted to explore nurses' positive experiences in caring for older adults with dementia in South Korea. Researchers collected data through in-depth, face-to-face interviews, and the recorded interviews were analyzed using grounded theory. A total of 33 codes, 12 categories, and 21 sub-categories were derived, and the categories were further analyzed using the paradigm model. A conceptual framework, the
Gratified in Caring Model
, was developed by integrating and abstracting the core category from nurses' positive experiences, and can be used by nurses to provide effective care and educators to train nurses to care for older adults. Findings also emphasize the need for nurses to collaborate with family members, as collaboration has been found to influence nurses' positive experiences. [
Journal of Gerontological Nursing, 45
(1), 31–37.]
Uveitis in Childhood
Authors: Kadayifçilar Sibel , Eldem Bora , Tumer Burak
Published: January 2019

ABSTRACT

Purpose: To review the etiologic factors and complications of uveitis in patients younger than 16 years.

Patients and Methods: Between January 1989 and December 1999 in the Department of Ophthalmology of Hacettepe University School of Medicine, 219 patients were diagnosed or observed as having pediatric uveitis. After complete ocular and physical examinations, routine and specific laboratory and radiologic investigations were performed. Medical or surgical treatment was employed when necessary.

Results: Of the 219 patients, 112 were girls, with a mean age of 7.4 ± 4.2 years, and 107 were boys, with a mean age of 8.3 ± 3.4 years. In 24.2% of the cases, no etiologic factor could be ascertained; these cases comprised the idiopathic group. Among the remaining cases, the most common etiologies were toxoplasmosis, juvenile rheumatoid arthritis ORA), pars planitis, Behçet's disease, and Fuchs' heterochromic iridocyclitis. Anatomically, anterior uveitis was the most common form. The mean follow-up time was 37 ± 6.2 months. Complications for which surgical treatment was employed were identified in 71 eyes (20.9%), most of which were due to JRA, pars planitis, or Behçet's disease.

Conclusion: Uveitis in childhood may be idiopathic or most commonly due to toxoplasmosis, JRA, and pars planitis. Due to inflammation itself or to prolonged therapy especially with corticosteroids, pediatric uveitis entities (mostly JRA, pars planitis, or Behçet's disease) may result in complications necessitating a surgical approach.

J Pediatr Ophthalmol Strabismus 2003;40:335-340.
Oral Fluorescein Angiography in Patients With Choroidal Neovascularization and Macular Degeneration
Authors: Bartsch Dirk-Uwe , Elmusharaf Abbas , El-Bradey Mohamed , Freeman William R
Published: January 2019

* OBJECTIVE: To evaluate image quality of oral fluorescein angiography in patients with age-related macular degeneration and choroidal neovascularization.

* MATERIALS AND METHODS: Twenty four patients with proven choroidal neovascularization were examined in a prospective observational case series. Confocal oral and intravenous fluorescein angiography were performed using the Heidelberg Retina Angiograph. Oral and intravenous image quality were compared in a masked fashion.

* RESULTS: Choroidal neovascularization could be diagnosed in all patients using intravenous angiograms. Oral fluorescein angiography accurately detected the presence or absence of choroidal neovascularization in all patients and could determine the classification of choroidal neovascularization, location, and extent and borders in 20 (83.3%) of 24 patients. Early, mid, and late phases of oral angiograms occurred at 8, 15, and 26 minutes, respectively.

* CONCLUSION: Oral fluorescein angiography using the confocal Heidelberg Retina Angiograph allowed detection of choroidal neovascularization in all patients in this study. Visualization of extent and type of choroidal neovascularization was possible in most eyes with choroidal neovascularization. These findings suggest oral angiography is an excellent screening tool for choroidal neovascularization and allows guidance of treatment in the majority of cases.

[Ophthalmic Surg Lasers Imaging 2003;34: 17-24]
Photodynamic Therapy of Polypoidal Choroidal Vasculopathy
Authors: Rogers Adam H , Greenberg Paul B , Martidis Adam , Puliafito Carmen A
Published: January 2019

Abstract. Polypoidal choroidal vasculopathy is an abnormality of the choroidal vasculature characterized by aneurysmal-like budding of the vessels with exudation and recurrent serosanguinous detachments of the retinal pigment epithelium. Treatment is limited to laser photocoagulation of leaking vessels, which is used when vision is decreased, or exudate and hemorrhage threaten or involve the fovea. This article describes a patient with polypoidal choroidal vasculopathy successfully treated with photodynamic therapy using verteporfin. [Ophthalmic Surg Lasers Imaging 2003; 34:60-63]
Confocal Microscopy in Late-Onset Diffuse Lamellar Keratitis After Laser In Situ Keratomileusis
Authors: Silva Victoria de Rojas , Rodríguez-Ares Teresa , Díez-Feijóo Elío , Sánchez-Salorio Manuel
Published: January 2019

Abstract. This article reports a case of diffuse lamellar keratitis, without exposure of the flap interface, that developed in a patient who underwent intraepithelial photorefractive keratectomy 1 year after bilateral LASIK. Confocal microscopy was performed in both eyes at the onset of the dimise lamellar keratitis and after its resolution. In the eye with diffuse lamellar keratitis, abundant round structures (inflammatory cells) were present at the interface; these structures disappeared after the keratitis resolved and were not present in the contralateral eye at any time. These confocal microscopic findings further support the hypothesis that diffuse lamellar keratitis is a nonspecific inflammatory response in corneas with a lamellar interface. [Ophthalmic Surg Lasers Imaging 2003;34:68-72]
A New Silicone Eyecup for Ultrasound Biomicroscopy
Authors: Tran H Viet , Ishikawa Hiroshi , Liebmann Jeffrey M , Ritch Robert
Published: January 2019

Abstract. This study compared a new disposable silicone eyecup for high-frequency ultrasound biomicroscopy to the standard hard plastic eyecup. The results showed the silicone eyecup attenuated leakage of the medium in which the probe was immersed, decreased scanning time, decreased distortion of the iris and angle during scanning, enhanced image quality, and improved patient comfort. These findings indicate the silicone eyecup is a good alternative to the hard plastic eyecup and also is easier to use. [Ophthalmic Surg Lasers Imaging 2003;34:73-75]
Late-Onset Bacterial Endophthalmitis Following Glaucoma Drainage Implantation
Authors: Francis Brian A , DiLoreto David A , Chong Lawrence P , Rao Narsing
Published: January 2019

Abstract. A clinicopathologic report of late-onset bacterial endophthalmitis 4 years after implantation of a Baerveldt drainage implant is described. An 80-yearold woman with glaucoma presented 8 years after tube shunt implantation with clinical endophthalmitis. During surgical removal of the implant, a small conjunctival buttonhole caused by the suture securing the plate to the sclera was noted to be the only entry site. Vitreous and anterior chamber taps were performed with intravitreal antibiotics. Cultures revealed Streptococcus pneumoniae infection. The pathologic analysis showed epithelialization of the conjunctival buttonhole and diffuse ocular inflammation, mucopurulent material, and fibrovascular membranes. Due to severe pain, the eye was enucleated after 1 week. [Ophthalmic Surg Lasers Imaging 2003;34:128-130.]
Nd:YAG Laser Photocystotomy of a Free-Floating Pigmented Anterior Vitreous Cyst
Authors: Gupta Rajeev , Pannu Bir Kamal Singh , Bhargav Sonia , Narang Subina , Sood Sunandan
Published: January 2019

Abstract. An 8-year-old girl presented with a free-floating pigmented cyst in the anterior vitreous causing a large, visually disturbing floater. A simple laser photocystotomy with a single-frequency Nd:YAG laser resulted in a reduction in the size of the cyst but persistence of the floater. An attempt at further laser fragmentation of the cyst resulted in iatrogenic cataract formation. [Ophthalmic Surg Lasers Imaging 2003;34:203-205.]
Delayed Suprachoroidal Hemorrhage Following Viscocanalostomy
Authors: Cheema Rizwan A , Choong Yee F , Algawi Kais D
Published: January 2019

Abstract. Delayed suprachoroidal hemorrhage is a rare complication of conventional glaucoma surgery. Viscocanalostomy is one of the new surgical techniques used in glaucoma surgery that may theoretically protect against suprachoroidal effusion and hemorrhage due to the nonpenetrating nature of the procedure. Delayed suprachoroidal hemorrhage developed in a 92-year-old white woman following viscocanalostomy. This case demonstrates that the risk of suprachoroidal hemorrhage may not be completely eliminated after a nonpenetrating glaucoma procedure such as viscocanalostomy. [Ophthalmic Surg Lasers Imaging 2003;34:209-211.]
Graphic Representation of Data Resulting From Measurement Comparison Trials in Cataract and Refractive Surgery
Authors: Krummenauer Frank , Storkebaum Kristin , Dick H Burkhard
Published: January 2019

* BACKGROUND AND OBJECTIVES: The evaluation of new diagnostic measurement devices allows intraindividual comparison with an established standard method. However, reports in journal articles often omit the adequate incorporation of the intraindividual design into the graphic representation.

* PATIENTS AND METHODS: This article illustrates the drawbacks and the possible erroneous conclusions caused by this misleading practice in terms of recent method comparison data resulting from axial length measurement in 220 consecutive patients by both applanation ultrasound and partial coherence interferometry.

* RESULTS: Graphic representation of such method comparison data should be based on boxplots for intraindividual differences or on Bland-Altman plots. Otherwise, severe deviations between the measurement devices could be erroneously ignored and false-positive conclusions on the concordance of the instruments could result.

* CONCLUSION: Graphic representation of method comparison data should sensitively incorporate the underlying study design for intraindividual comparison.

[Ophthalmic Surg Lasers Imaging 2003;34:240-244.]
High-Frequency Ultrasonographic Imaging in Suprachoroidal Hemorrhage After Filtering Surgery
Authors: Okamoto Fumiki , Yamamoto Narumichi , Iguchi Aya , Komahashi Mikako , Hommura Sachiko , Oshika Tetsuro
Published: January 2019

Abstract. A 64-year-old woman with glaucoma had suprachoroidal hemorrhage approximately 6 hours after trabeculectomy. High-frequency ultrasonography revealed high reflectivity in the inner space of a kissing choroidal detachment, which facilitated the differential diagnosis of suprachoroidal hemorrhage resulting from serous choroidal detachment. The ciliary process and iris were anteriorly displaced due to the ciliary detachment and forward pressure of the anterior vitreous. On the basis of the diagnosis, transscleral choroidal drainage was performed without delay and the patient's vision was preserved. After surgery, suprachoroidal hemorrhage disappeared clinically, but high-frequency ultrasonography detected persistence of the choroidal detachment in the peripheral area. [Ophthalmic Surg Lasers Imaging 2003;34:259-262.]
Visual Functions Following Recovery From Non-Arteritic Central Retinal Artery Occlusion
Authors: Landa Elina , Rehany Uri , Rumelt Shimon
Published: January 2019

* BACKGROUND AND OBJECTIVE: Visual acuity and other visual functions may improve following treatment of central retinal artery occlusion (CRAO). A prospective, noncomparative case series study was conducted to investigate patients' visual functions after treatment of non-arteritic CRAO.

* PATIENTS AND METHODS: Eight consecutive patients whose visual acuity improved following successful systematic treatment protocol for non-arteritic CRAO of less than 48 hours (one of them with patent cilioretinal artery) were evaluated for visual functions. The visual acuity in seven patients ranged from no light perception to counting fingers at 3 feet on presentation and improved to 20/ 1 00 to 20/20 following treatment. The visual tests included: blue- yellow (Farnsworth D. 15) and green-red (pseudoisochromatic Ishihara color plates) color discrimination, contrast sensitivity, and visual fields. The patients were also evaluated for subjective daily function following treatment. All tests were also performed in the fellow uninvolved eye as a control.

* RESULTS: The visual acuity following treatment improved from no light perception to counting fingers at 3 feet to an average of 20/65 (range, 20/20 to 20/100). Despite this improvement, six patients had dyschromatopsia to blue, green, or red whereas only two patients with a final visual acuity of 20/20 preserved their ftill color discrimination. All patients had decreased contrast sensitivity at mid-spatial frequency (6 cycles/min) or a more generalized decrease and visual field defects. All of the patients except one were satisfied with the visual outcome and daily function after treatment.

* CONCLUSION: Despite improvement in visual acuity after treatment for CRAO, all patients had residual visual function abnormalities. These abnormalities may be attributed to partial recanalization, conversion of CRAO to multiple branch retinal artery occlusions, or different retinal susceptibility for ischemia.

[Ophthalmic Surg Lasers Imaging 2004;35:103-108.]
Indocyanine Green Angiography in High Myopia
Authors: Axer-Siegel Ruth , Cotlear Daniel , Priel Ethan , Rosenblatt Irit , Snir Moshe , Weinberger Dov
Published: January 2019

* BACKGROUND AND OBJECTIVE: To evalu ate indocyanine green imaging of choroidal changes in pathologic myopia and to compare it with fluorescein angiography.

* PATIENTS AND METHODS: The angiograms of all consecutive patients with pathologic myopia photographed with confocal indocyanine green angiography using a scanning infrared laser or ophthalmoscope from March 1997 to December 1999 were reviewed.

* RESULTS: Twenty-one patients (35 eyes) were included. Indocyanine green angiography was performed in 35 eyes and immediate sequential fluorescein angiography and indocyanine green angiography in 25 eyes. The lacquer cracks were demonstrated to radiate from the disc, at the papillomacular bundle, through the macula, and around the macula. Lacquer cracks were identified in 89% and 28% of the eyes, respectively. Choroidal neovascularization (CNV) was demonstrated in 57% of eyes by indocyanine green angiography and in 56% by fluorescein angiography. All of the CNVs were classic and were located within 300 pm of the foveal center. Seventy percent of the CNVs were delineated in lacquer cracks by indocyanine green angiography. Overall, 124 lacquer cracks were identified by indocyanine green angiography and only 14 by fluorescein angiography. Lipids or serous detachment were not observed. Retinal hemorrhages were noted in 22% and 28% of eyes with indocyanine green angiography and fluorescein angiography, respectively.

* CONCLUSION: Confocal indocyanine green angiography offers better delineation of lacquer cracks and the localization of the CNV in lacquer cracks than does fluorescein angiography.

[Ophthalmic Surg Lasers Imaging 2004;35:139-145.]
White-Light and Laser Confocal Microscopic Findings of Rabbit Conjunctiva
Authors: Kobayashi Akira , Yoshita Tsuyoshi , Sugiyama Kazuhisa
Published: January 2019

* BACKGROUND AND OBJECTIVE: To report laser and white-light confocal microscopic findings of ex vivo rabbit conjunctiva to investigate the potential application of these confocal microscopes as diagnostic devices for normal and pathologic conjunctiva.

* MATERIALS AND METHODS: Three male albino rabbits were killed and six eyeballs were removed with as much bulbar conjunctiva as possible. The bulbar conjunctiva approximately 5 mm away from the limbus was then subjected to an ex vivo laser and white-light confocal microscopic analysis.

* RESULTS: Using laser confocal microscopy, conjunctival epithelial cells, subepithelial conjunctival vessels, and sclera were clearly observed. By contrast, white-light confocal microscopy yielded images of conjunctival epithelium, subepithelial layers, and sclera that were not clearly defined.

* CONCLUSIONS: This study indicates that laser confocal microscopy has a superior ability to visualize ex vivo, non-fixed conjunctiva when compared with white-light confocal microscopy. It also suggests that the laser confocal microscope might be a useful, noninvasive, in vivo, "quasi-cytological" device for observing and diagnosing the conjunctival condition in humans.

[Ophthalmic Suig Lasers Imaging 2004;35:146-148.]
Tomographic Features of Serous Retinal Detachment in Vogt-Koyanagi-Harada Syndrome
Authors: Maruyama Yasuhiro , Kishi Shoji
Published: January 2019

Abstract. To clarify the nature of serous retinal detachment in Vogt- Koyanagi- Harada (VKH) syndrome, 42 consecutive eyes of 21 patients with acute phase VKH syndrome were examined using optical coherence tomography (OCT). OCT revealed two patterns of serous retinal detachment. Twenty-nine eyes (69%) had a true retinal detachment, 17 eyes (40%) had intraretinal fluid accumulation in the outer retina, and 4 eyes had both. Intraretinal fluid accumulation appeared as an oval space in the outer retina. On fluorescein angiography, the eyes with intraretinal fluid accumulation showed more severe dye leakage from the retinal pigment epithelium. [Ophthalmic Surg Lasers Imaging 2004;35:239-242.]
Pars Plana Vitrectomy and Lamina Cribrosa Puncture in Absolute Glaucoma
Authors: Quiroz-Mercado Hugo , Alvarez-Celorio Dolores , Martinez-Jardon Susana , Guerrero-Naranjo Jose Luis , Gil-Carrasco Felix , Solis Soledad , Cekic Osman
Published: January 2019

Abstract. Two patients with refractory end-stage glaucoma who had no light perception underwent pars plana vitrectomy and lamina cribrosa puncture to relieve pain and decrease intraocular pressure. The patients presented with blind, painful eyes and high intraocular pressure (> 40 mm Hg). After the procedure, the pain was relieved and the intraocular pressure was lowered in both cases. The patients remained asymptomatic. Pars plana vitrectomy and lamina cribrosa puncture might be related to the decrease of intraocular pressure, probably by facilitating drainage of aqueous humor through the optic nerve. [Ophthalmic Surg Lasers Imaging 2004;35:244-246.][
Malignant Glaucoma as a Complication of Nd:YAG Laser Posterior Capsulotomy
Authors: Arya Sudesh Kumar , Sonika  , Kochhar Suman , Kumar Suresh , Kan Meena , Sood Sunandan
Published: January 2019

Abstract. A 79-year-old woman with pseudophakia who underwent Nd:YAG posterior capsulotomy for posterior capsular opacification in her right eye had increased intraocular pressure associated with a flat anterior chamber. Full-thickness patent iridotomy performed with an Nd:YAG laser did not reduce the intraocular pressure. B-scan ultrasonography showed aqueous pockets in the vitreous, leading to a diagnosis of malignant glaucoma. Medical and surgical therapy normalized the intraocular pressure and resolved the symptoms of malignant glaucoma. [Ophthalmic Surg Lasers Imaging 2004;35:248-250.]
A New Surgical Approach for Indocyanine Green-Assisted Internal Limiting Membrane Peeling
Authors: Avci Remzi , Avci Berrin , Kaderli Berkant , Cavusoglu Ilkin
Published: January 2019

* BACKGROUND AND OBJECTIVE: The efficiency of indocyanine green (ICG) dye in the removal of the internal limiting membrane (ILM) with a fluid needle using passive aspiration was evaluated.

* PATIENTS AND METHODS: Eighteen consecutive patients with diffuse diabetic macular edema were studied. After vitrectomy and total fluid- air exchange, 0. 1 mL of ICG solution 0.25% was left in the macular area for 1 minute. Then the macular ILM was peeled with a specially designed tapered fluid needle using passive aspiration.

* RESULTS: In 16 of the 18 eyes, the peeling procedure could be easily performed with a tapered fluid needle using passive aspiration. In 1 1 eyes, partial development of spontaneous ILM detachment prior to the peeling process was also observed.

* CONCLUSIONS: ICG solution 0.25% appears to reduce the adhesive force of the ILM to the sensory retina, which makes the removal of the ILM much easier by passive aspiration with a fluid needle.

[Ophthalmic Surg Lasers Imaging 2004;35:292-297.]