bluuebunny/crossref_metadata_2025 huggingface dataset:
Akuzativne klitike u bosanskom jeziku
Authors: Resić Elmira
Published: December 2024

U ovom se radu analizira sintaksički status akuzativnih klitika u bosanskom jeziku i njihovo pomjeranje u tzv. drugu poziciju (engl. second position clitics / Wackernagel clitics) s teorijskog polazišta tzv. minimalističkog programa (engl. Minimalist Program, Chomsky 1995; 2000; 2001). Derivacija sintaksičkih struktura posmatra se kroz djelovanje sintaksičke operacije spajanja (engl. Merge) i sintaksičke operacije slaganja (engl. Agree). Pri tome, u radu se slijedi tzv. teorija faza (engl. Phase Theory, Chomsky 2001), koja postulira da se derivacija sintaksičke strukture odvija u fazama koje omogućavaju da se minimalni dijelovi strukture sukcesivno šalju u tzv. Spell-out, odnosno u interfejs u kojem dolazi do razdvajanja informacija relevantnih za nivo fonetskog (engl. Phonetic form, PF) i logičkog predstavljanja (engl. Logical form, LF). U radu se zastupa hipoteza da se akuzativne klitike izvorno generiraju u poziciji komplementa glagola za koji su tematski vezane te da, budući da nemaju status fraznih afiksa, ne mogu biti sintaksički spojene s tim glagolom. U tom se smislu transfer akuzativnih klitika u PF komponentu dešava već u vP fazi, dok glagol za koji je klitika tematski vezana nije obuhvaćen ovim transferom jer se pomjera u tzv. rubnu poziciju (engl. edge position) vP faze. Cilj je ovoga rada pokazati da je tzv. druga pozicija akuzativnih klitika rezultat njihovog postsintaksičkog pomjeranja koje slijedi nakon prozodijskog organiziranja strukturnih elemenata na PF nivou. Akuzativne klitike pomjeraju se u tzv. drugu poziciju u svojoj intonacijskoj frazi (engl. Intonation phrase, IP), pri čemu intonacijska fraza korespondira s granicama CP domene klauze koja sadrži akuzativne klitike. Pozicija akuzativnih klitika iza prve naglašene riješi (engl. first word position, 1W) ili iza prvog sintaksičkog konstituenta (engl. first constituent position, 1C) u vezi je s (ne)postojanjem prozodijskih barijera.
Pendekatan Konseling Behavioral pada Kasus Dugaan Ujaran Kebencian dan Penodaan Agama Yahya Waloni
Authors: Oktaviawati Monita
Published: December 2024

This research aims to discuss the behavioral counseling approach that focuses on the case of hate speech and blasphemy against Yahya Waloni that sparked public debate. In behavioral theory humans are seen as neutral beings who are not good and not bad so that behavioral counseling centers on individuals to produce more positive behavioral changes. This research uses descriptive qualitative with library research-based data collection methods with descriptive collaboration methods the author explains about hate speech and its impact on religious harmony in Indonesia. The results show that the behavioral counseling approach can be an effective method because it focuses on behavior modification and encourages positive change. This approach centers on the stimulus and individual response to situations to reduce aggressive behavior.
Hubungan Regulasi Emosi dengan Prokrastinasi Akademik Pada Siswa
Authors: Mutiâ€™ah Aulia , Wisma Nur , Mega Putri Rani
Published: December 2024

The Covid-19 era has brought new habits for students, one of which is taking work as a relaxing activity. This arises because of the comfort zone that was formed to entertain oneself in that era. However, this has negative effects on students' academic aspects, for example academic procrastination. Academic procrastination is influenced by many factors, one of which is emotional regulation. A preliminary study conducted with student interviews at SMAN 10 Palembang showed that students can regulate emotions but they still carry out academic procrastination. This research was carried out using a quantitative correlational model method because it wanted to examine whether or not there was a relationship between emotional regulation and students' academic procrastination and was carried out by distributing questionnaires to 85 students as a sample. The results obtained in this research are the most data at the level of emotional regulation 72% and academic procrastination 69%, which is in the "medium" category and produces -0.057 as a Spearman rank correlation value which shows that there is a very weak and unidirectional relationship between emotional regulation and Academic procrastination in class.
Nilai-Nilai Penguatan Pendidikan Karakter Berbasis Neurosains dalam Pembelajaran Akidah Akhlak di SD Negeri Serayu
Authors: Us'an Us'an , Putra Armando Bima
Published: December 2024

This research examines the values of strengthening neuroscience-based character education in learning moral beliefs at Serayu State Elementary School. Moral beliefs are a subject that emphasizes the ability to understand faith, manners, and the good relationship between humans and God. However, learning moral beliefs tends to touch the cognitive domain which is limited to material mastery, while the affective domain is forgotten. Therefore, the aim of this research is to find a new concept in instilling character values in the learning of moral beliefs. This research uses a qualitative approach with descriptive methods. Data collection techniques include interviews, observation and documentation. Researchers use data analysis by collecting data, reducing data, presenting data, and drawing conclusions. The data that has been collected is then described and given meaning, from that meaning a conclusion is drawn. The results of this research show the values of strengthening neuroscience-based character education in learning moral beliefs, namely: regulatory religious values from the temporal lobe of the brain, regulatory mutual cooperation values from the cingulate gyrus and basal ganglia, regulatory nationalist attitudes from the prefrontal cortex, regulatory integrity attitudes from the system. limbic, and self-regulatory attitudes of the cerebellum. If neuroscience-based character education in moral belief lessons is carried out optimally, then this character education can be achieved optimally. The reason is that changing students' behavior is more effective by changing their brains first.
Konseling Individu dengan Pendekatan Behavioral bagi Pelaku Kekerasan Seksual di UPTD PKS Insan Berguna
Authors: Fitriyanti Risma , Nasution Sri Ilham , Mawarni Anisa
Published: December 2024

This research aims to describe the implementation stages of individual counseling using a behavioral approach for perpetrators of sexual violence at the UPTD PKS Insan Berguna, Lampung Province Social Service. Children involved in sexual violence need a more advanced approach, such as through guidance and counseling that focuses on recovery. Individual counseling is effective because it involves direct interaction between the counselor and the client, allowing the counselor to pay more in-depth attention to the problems faced by the client. The method used in this research is a field research method. Data collection techniques in this research used observation, interviews and documentation. The results obtained in this research show that individual counseling with a behavioral approach has an effect on changing clients' good behavior. The main focus of this research is to describe the behavior patterns of these children, as well as the changes that occur in the rehabilitation process carried out at that place. Researchers also try to explain how a counseling process based on a behavioral approach can help these children identify and change their behavior patterns to be more positive. And clients are starting to realize the impact of their bad habits and are actively working to change them. After attending this counseling, the three clients realized their mistakes and will now try to change for the better. Individual counseling with a behavioral approach shows effectiveness in dealing with behavioral problems, but also emphasizes that self-awareness is an important first step in efforts to improve lifestyle. Furthermore, the behavioral changes achieved by clients during the counseling process provide hope that this kind of intervention can contribute to a sustainable improvement in their quality of life.
Evaluation of Cassava Leaf Paste on Egg Performance and Egg Quality of Quail Egg Laying Period
Authors: La Jumadin  , Aryani Sismin Satyaningtijas  , Hera Maheshwari  , Niken Ulupi  , Dwi Nurhidayah Zubaidah  , Maryce Agusthinus Walukou  , Lili Darlian  , Damhuri  , Koekoeh Santoso
Published: December 2024

Quail has a high egg production. On the other hand, quail has a weakness, which is prone to stress. This stress is caused by erratic weather conditions. This study examines and evaluates the role and function of cassava leaf paste on aspects of egg performance and egg quality of quail eggs in the laying period that are reared under natural conditions or normal conditions in tropical areas, such as in Indonesia. Observation of egg performance was detected by calculating egg length, egg width, and egg shape index. Observation of egg quality aspects was detected by calculating the quality of the shell, egg white, and egg yolk. The results showed that the shape index of quail eggs at various levels of cassava leaf paste administration showed results that were not significantly different. The egg shape index obtained at P2 and P3 tends to be more oval/semi-tapered, while at P0 and P1 it tends to be round. The value of the eggshell weight, egg white weight, and egg yolk weight that received cassava leaf paste were higher than the control treatment. The high eggshell weight, egg white weight, and egg yolk weight were suspected to be differences in nutritional content, mineral elements, and flavonoids between treatments. Giving cassava leaf paste can increase the index of egg shape in the quail laying period. The application of cassava leaf paste can also increase the weight of the shell, the weight of the egg white, and the weight of the yolk in the egg-laying period of quail.
Dinamika Bakteri Vibrio spp. pada Air Laut di Seputar Sentra Pembenihan Udang Vanamei (Litopenaeus vannamei) di Indonesia
Authors: Rubiyanto Widodo Haliman  , Edi Poncolaksito  , Sujarwo Sujarwo  , Ismawi Ismawi  , Awan Kunadi  , Nuzuliah Wahyu Berutu  , Dwi Retno Untari  , Sarayut Srisombat  , Beni Halalludin  , Rizkiantino Rifky , Fivi Najmushabah  , Hendri Laiman
Published: December 2024

Bakteri Vibrio spp. adalah salah satu patogen yang umum menginfeksi pembenihan dan pembesaran udang, yang dapat menyebabkan kematian masal benur di panti benih udang. Penelitian ini bertujuan untuk mengetahui dinamika bakteri Vibrio spp. pada air laut di seputar tujuh area sentra pembenihan udang vanamei di Indonesia. Pengamatan dilakukan setiap bulan sejak Januari hingga Desember 2020, dengan menginokulasikan 100 µL sampel air laut ke media agar thiosulfate-citrate-bile-salt sucrose (TCBS), diinkubasikan pada suhu 30°C selama 18–24 jam, setelah itu dilakukan penghitungan koloni Green Vibrio Colony (GVC), Total Vibrio Count (TVC), dan persentase kejadian bakteri berpendar pada sampel air laut. Hasil pengamatan menunjukkan bahwa angka GVC dan TVC tertinggi terjadi di perairan Takalar pada bulan Mei 2020, sedangkan persentase sampel air laut dengan bakteri yang berpendar paling tinggi terjadi pada sampel dari perairan Pantai Cermin-Serdang Bedagai. Nilai GVC berkisar antara 0,01–130,00 × 102 CFU/mL dengan angka tertinggi terjadi pada bulan Januari, Oktober, November, dan Desember 2020, sedangkan nilai TVC berkisar antara 0.20–520.00 × 102 CFU/mL sepanjang tahun 2020. Tidak ditemukan adanya bakteri berpendar pada sampel air laut dari daerah Anyer dan Pangandaran. Para operator panti benih udang vanamei perlu senantiasa waspada terhadap dinamika populasi bakteri Vibrio spp. pada air laut yang akan dipakai dalam kegiatan pembenihan udang vanamei.
Effect of subacute administration of orange juice (Citrus sinensis) on duodenal structure in paediatric Sprague-Dawley rats (Rattus novergicus)
Authors: Yan Teo Qin , Hendry Altaff , Andre Daniel Latief , Rahman Muhammad Luthfi , Rudramurti Win Satya , Permana Nadine Hanifa , Utami Dian Maulia , Pristihadi Diah Nugrahani , Setiyono Agus
Published: December 2024

This research investigates the impact of orange juice consumption on the histological structure of the duodenum, a critical site for nutrient absorption and digestion. Focusing on pediatric animals, orange juice (with a pH of 3) was administered to post-weaning rats aged 4 weeks to 6 weeks at dosages ranging from 0g/kg BW to 20g/kg BW over two weeks. Duodenal histopathology was assessed, focusing on parameters such as the quantity of crypts of Lieberkuhn, as well as the length, height, width, and depth of villi (measured in μm). Anatomical pathology examination included measurements of the length and width of the duodenum (also in μm), as well as the color mean (OD). The research findings indicate no significant changes in histo-pathology or anatomy pathology of the duodenum. This suggests that young individuals can adapt to acidic challenges without compromising gastrointestinal health. These findings offer reassurance regarding the short-term consumption of acidic orange juice (with a pH of 3) with minimal risks to intestinal integrity, both during growth and development.
Identification and antibiotic resistance testing of Gram-negative rod-shaped bacteria in birds of paradise (Paradisaeidae sp.)
Authors: Parameshtya Sadhira , Wijaya Agus , Safika Safika
Published: December 2024

Antibiotic resistance represents a critical global health challenge, and is characterised by the loss of effectiveness of antibiotics against bacterial growth. This phenomenon complicates treatment options for infections, underscoring the need to understand bacterial resistance mechanisms, particularly in protected species such as birds of paradise. This study aimed to identify the bacterial species present in faecal samples from three different species of birds of paradise and evaluate the efficacy of various antibiotics against these bacteria. Samples were collected from Taman Mini Indonesia Indah (TMII) in East Jakarta. Using MacConkey Agar for bacterial isolation and subsequent identification through Gram staining and biochemical tests, this study identified Serratia sp., Klebsiella sp., and Citrobacter sp. Antibiotic susceptibility was assessed using the Kirby-Bauer disk diffusion method against seven antibiotics: erythromycin, gentamicin, oxytetracycline, cefotaxime, sulfamethoxazole, doxycycline, and nalidixic acid. These findings revealed that sulfamethoxazole was notably more effective than the other antibiotics tested, highlighting its potential for treating infections in birds of paradise.
Faktor yang Mempengaruhi Aliran Perdagangan Produk antar Negara ASEAN
Authors: Fadhilah Alfirah , Rifin Amzul , Nurmalina Rita
Published: December 2024

International Trade is an important indicator for a country to increase economic growth and as an instrument to drive the economy through Gross Domestic Product. A country's economic growth can be encouraged through cooperation between countries in international trade in the form of economic integration. ASEAN economic integration is an effort to unite and deepen economic relations between ASEAN member countries. This research aims to answer questions that arise, namely to analyze the factors that influence the flow of product trade between ASEAN countries. The data used in this research consists of export and import trade data between ASEAN countries, the GDP of each ASEAN country, GDP per capita of ASEAN countries, the population of each ASEAN country, exchange rates, and economic distance. This research analyzes the factors that influence the flow of product trade between ASEAN countries. The data used is panel data with annual time series for the last 10 years, namely 2012 to 2022. The research results show that the GDP per capita variables of the country of origin and intra-ASEAN partner countries, the population of the country of origin and intra-ASEAN partner countries have a positive and significant effect on the flow of product trade between ASEAN member countries. Meanwhile, the variables GDP of the origin country, GDP of the partner country, exchange rate, and economic distance do not have a significant influence on the flow of trade between ASEAN member countries.
Tingkat Penerapan Materi dan Partisipasi Petani pada Sekolah Lapang Climate Smart Agriculture Di Kabupaten Jember
Authors: Irvandika Fachriza , Suciati Luh Putu
Published: December 2024

The Climate Smart Agriculture program aims to educate farmers in preventing the negative impacts of climate change through the Climate Smart Agriculture Field School (SL-CSA). The success of Climate Smart Agriculture requires the level of application of SL-CSA materials and farmer participation. The study aims to analyze the level of application of SL-CSA materials and farmer participation in the Climate Smart Agriculture Field School in Ambulu District, Jember Regency. The study was conducted in Ambulu District which has the Talang and Pondok Waluh Irrigation Areas which are the requirements for the implementation of SL-CSA. Data collection methods were observation, documentation studies and interviews. The research respondents were farmers participating in the SL-CSA in Ambulu District. Data were analyzed using Scoring and Spearman Rank Correlation analysis. The results showed that the level of application of materials by SL-CSA farmers in Ambulu District was categorized as high. The level of application of materials by farmers can be seen from the materials provided in SL-CSA that have been applied by several farmers. Several farmers who did not apply were constrained by finances and farmer awareness. The level of farmer participation in SL-CSA in Ambulu District was categorized as high. The level of farmer participation in SL-CSA can be reviewed at the level of farmer attendance and activity in each SL-CSA activity. The frequency of attendance and farmer activity are significantly correlated and have a positive direction with the level of application of materials by farmers. Internal characteristics (age and education level) and external characteristics (land area, employment status, land ownership and productivity level) are not significantly correlated and have a negative direction.
Keberlanjutan Pertanian Berbasis Pesantren di Kota Tasikmalaya
Authors: Ismi M. Jorgy Lazuardi Labunove , Nuryati Rina , Hikmah Widi Riantin
Published: December 2024

The phenomenon of Islamic boarding schools today is to add life skills in their learning. Providing life skills aims to equip students in terms of skills, especially in the agricultural sector. The learning must be clearly structured and directed to ensure social, economic, ecological, regulation and institutional sustainability. The importance of sustainability is to maintain the existence of pesantren-based agriculture. This research aims to identify the sustainability of pesantren-based agriculture in Tasikmalaya City. It was conducted from January to July 2024 at Pesantren Islamic Leader School and Pesantren Hidayatul Mustafid. Primary data collection used survey method by interviewing 132 respondents and 2 key informants. Secondary data were obtained from statistical data of related agencies. The analytical tools used were descriptive analysis and Rapid Aparsial for Pondok Pesantren (Rap-Pontren) to diagnose sustainability. Based on the findings of the analysis, Islamic boarding school agriculture is classified as quite sustainable for the social and ecological dimensions, this is due to the seriousness of the Islamic boarding school in managing agriculture so that they produce superior commodities. However, it is less sustainable for the economic, regulation and institutional dimensions, this is because agricultural institutions related to pesantren have not been formed so that the flow of costs and revenues has not been clearly recorded.
Analisis Indeks Komplementaritas Perdagangan Produk Pertanian Pada Regional Comprehensive Economic Partnership (RCEP)
Authors: Putri Rahma Meiliza
Published: December 2024

This research uses simple descriptive analysis and a trade complementarity index to examine the Indonesia-RCEP agricultural trade relationship for the 2010-2019 period to predict future trade conditions for Indonesia RCEP. Based on the trade balance, starting from 2016 there has been an increase in trade exports, even in the last 4 years Indonesia has continued to experience a surplus of USD 36.93 billion. Throughout the decade, there was a match between the export supply of Indonesian agricultural products and the demand for imports of RCEP agricultural products because the agricultural product trade complementarity index was located between 86.95 and 90.09. The country with the highest TCI value compared to Indonesia is Singapore, whereas the country with the lowest TCI is Brunei Darussalam. The history of high TCI values has been proven to be followed by increasing in exports of agricultural products in 2020 to 2022 of up to 11 percent. The main exports of agricultural products with the highest TCI values are live animals (HS 01), live trees and other plants (HS 06), and vegetable resins (HS 13). Through the results of this research, it can be recommended that efforts to increase Indonesian exports to RCEP require contributions and intervention from the Indonesian government. In particular, in the form of providing incentives so that agricultural resources that are not yet optimally used can be utilized. Apart from that, the government needs to optimize the use of FDI which is RCEP's superior product to maximize the quantity, quality of production, integration of knowledge and technology.
Analisis Keputusan Pembelian Mie Basah oleh Konsumen Muda di Kota Bogor
Authors: Ayu Rara Sekar , Krisnamurthi Bayu , Rachmina Dwi
Published: December 2024

The advancement of technology and society have led to changes including food choice patterns among citizens, especially the younger generation that prefers fast food. Noodles are included in one of the fast foods that young people opt for as it has diverse varieties. The decision-making process of purchasing noodles for young consumers is influenced by several driving factors. This study aims to analyze the decision-making process among young customers in Bogor while buying noodles, analyze factors that influence the decision-making while purchasing noodles in Bogor, and formulate managerial implications for the development of Noodles SMEs. Primary data from a survey of 95 respondents were analyzed using descriptive analysis and SEM-PLS analysis. The results indicate that consumers buy noodles primarily because they are fast and convenient while considering the taste of the product. Personal experience is the most influential factor in their purchasing decisions. There are four significant factors influencing the purchasing decisions of young consumers regarding wet noodles in Bogor, including product factors, distribution, promotion, and lifestyle. The distribution factor has the highest influence on consumer purchasing decisions with the highest correlation value. The efforts noodle SMEs in order to develop their businesses include maintaining and increasing the distribution of products as this factor is the most influential factor for customers to do the purchasing.
Pengaruh Persepsi Petani dan Peran Pendamping Terhadap Digitalisasi Pertanian Durian di Kecamatan Wonosalam Kabupaten Jombang
Authors: Firdaus Setiawan Risqi , Idhoh Fitriana Nisa Hafi , Susanto Heri
Published: December 2024

Agricultural digitalization is an innovative solution to face challenges in increasing the efficiency and productivity of the agribusiness sector. This process includes the use of information technology, such as the Internet of Things (IoT), data-based applications, and drones, to help durian farmers increase crop yields, reduce human error, and provide more accurate predictions regarding weather and durian crop conditions. This research aims to analyze the influence of farmers' perceptions and the role of assistants on the digitalization of durian farming in Wonosalam District, Jombang Regency. The research method used is a quantitative approach with the SEM-PLS analysis tool to test the relationship between latent variables. The respondents used in this research were 85 durian farmers in Wonosalam District. The research results show that durian farmers' perceptions have a significant influence on the adoption of agricultural digitalization. Meanwhile, the role of companions does not have a direct influence on digitalization, but significantly influences the perceptions of durian farmers. This confirms that effective mentoring can shape farmers' positive perceptions of digital technology, which ultimately increases adoption of the technology. Therefore, this research recommends that digital technology education and training programs for farmers be strengthened, with the aim of accelerating the agricultural digitalization process. It is hoped that these findings can provide input for policy makers in developing technology development strategies in the agricultural sector, especially durian commodities.
Determinant Factors Influencing the Interest in Halal Certification: The Perspective of MSMEs in Indonesia
Authors: Agustiningsih Maulida Dwi , Savitrah Ravika Mutiara , Islami Novita Nurul , Lestari Putri Catur Ayu
Published: December 2024

The halal industry is overgrowing, including in Indonesia, with the largest Muslim population in the world. Indonesia is ranked 19th as a producer and ranked 3rd as a consumer in the global halal industry. Although one of the halal certifications for MSMEs is free, only 1% of MSMEs in Indonesia are already halal certified. This study aims to analyze empirically the factors that influence the intensity of MSMEs in Indonesia to register for halal certification. A quantitative approach is used in this research by distributing questionnaires using the Likert scale to MSMEs. A total of 122 valid data collected were analyzed by adopting SEM-PLS. The analysis found that external factors had a dominant influence on the intention of MSMEs to register their products in halal certification, consumer pressure with a t-statistic of 4.328, and government policies with a t-statistic of 2.976. Moreover, one of the internal factors, awareness, is accepted with a t-statistic of 2.065. Meanwhile, benefits, competitors, and religiosity are not proven to affect halal certification. The data will help plan interventions from the government to encourage MSMEs to register their products in halal certification. The government should focus on assisting halal certification for MSMEs intensively.
Identification of Food Expenditure and Food Security of Muslim Households: Evidence from Indonesian Family Life Survey 2007 and 2014
Authors: Setiawati Nadya , Putri Ananda Sintia , Setiawan Agung
Published: December 2024

This study examines the impact of religiosity on household food consumption and food security in Indonesia, particularly among Muslim households. Despite the acknowledgment of religious factors in food-related policies, limited research has explored their specific influence on food expenditure and security. Using longitudinal data from the Indonesian Family Life Survey (IFLS) covering 2007 and 2014, this study analyzes food expenditure and food security levels among Muslim households, employing the Propensity Score Matching (PSM) model. The analysis includes variables such as age, education, marital status, employment, and gender. Findings reveal that religiosity negatively influences food expenditure, both in total and per capita, suggesting that religious households tend to spend less on food. Moreover, Muslim households demonstrate higher levels of food security, often reporting moderate or adequate food security, compared to non-religious households. This indicates a potential protective effect of religiosity on food stability. The study recommends integrating financial education programs that emphasize frugality and mindful consumption. Additionally, strengthening community-based support systems, such as zakat and sadaqah, could play a crucial role in improving food assistance and security.
Cost-effectiveness of budesonide-formoterol in maintenance therapy of asthma patients at Mexico’s National Center for Respiratory Diseases.
Authors: María del Carmen Cano-Salas  , José L. Miguel-Reyes  , Erika C. López-Estrada  , Jorge Salas-Hernández  , Monserrat E. Arroyo-Rojas  , Mauricio Castañeda-Valdivia  , Monserrat Escobar-Preciado  , Homero Garcés-Flores  , Silvia Guzmán- Vázquez  , Sergio R. García-García  , Herman Soto-Molina
Published: December 2024

Objective: to perform a cost-effectiveness analysis of asthma treatment with budesonide/formoterol against other treatment options used at Mexico’s National Institute for Respiratory Diseases.
Methods: A complete economic evaluation of cost-effectiveness from a public health perspective, comparing the use of budesonide/formoterol as maintenance therapy with fluticasone/vilanterol in 103 female asthma patients managed at INER between 2015 and 2021.
Results: Average cost per patient was $743.23 USD, $733.36 USD for budesonide/formoterol and $767.24 USD for fluticasone/vilanterol. Pharmacological treatment represented over 70% of management costs for both groups, followed by follow-up visits and exacerbation management costs. LABA-ICS represented the highest proportion of pharmacologic management costs with a statistically significant difference amongst groups with an incremental cost of $80.17 USD for the fluticasone/vilanterol group. The budesonide/formoterol group showed an ICER of $613.31 USD for reducing the proportion of patients experiencing exacerbations during follow-up. Considering the willingness to pay threshold based on one GDP per capita ($10,902.98 USD in 2022), budesonide/formoterol represented a very cost-effective option.
Conclusions: The ICER favored budesonide/formoterol over fluticasone/vilanterol in terms of cost-effectiveness. A 5.5% reduction in patient exacerbations indicated decreased disease burden. While not statistically significant, fewer exacerbations per patient might still cut costs by lowering emergency visits and hospitalizations.
Keywords: Cost-effectiveness analysis; Asthma; Budesonide; Formoterol fumarate.
Prevalencia de bronquiectasias en pacientes con errores innatos de la inmunidad
Authors: Korkowski Uviña Karla , Gómez Hernández Noemí , Quintero Ramos Antonio , Contreras Rodríguez Felipe de J. , Ortega Cisneros Margarita
Published: December 2024

Objective: To establish the prevalence of bronchiectasis, correlate the IgG IV or SC immunoglobulin dose and serum IgG levels with the total Bhalla score and the severity of bronchiectasis and associate serum IgG levels with the development of pulmonary infectious processes in patients with diagnosis of innate errors of immunity.
Methods: A descriptive, observational, cross-sectional study with patients over 18 years of age diagnosed with IBD. Clinical records and computed axial tomography were reviewed.
Results: 38 patients with IBD were included, where the prevalence of bronchiectasis was 36.8%. (Regarding the correlation of pulmonary infectious processes with serum IgG levels, a difference was found in patients from 2020 to 2022 (p= 0.002, 0.054, 0.030 respectively). The correlation of severity of bronchiectasis, total score of Bhalla scale, IgG IV or SC immunoglobulin dose and serum IgG levels by Spearman’s Rho test I were found to be significantly correlated.
Conclusion: It is important to perform chest tomography studies every 3-4 years in patients with IBD to detect timely bronchiectasis, initiate treatment in time, improving patients’ quality of life and survival rates, and reducing hospital costs.
Keywords: Bronchiectasis; IgG, Bhalla score; Inborn errors of immunity; Quality of life.
Angioedema hereditario tipo 1, limitaciones de la terapia profiláctica con lanadelumab: a propósito de un caso
Authors: Fonseca-Becerra Martha Lizeth , Betancur-Castro Juan Sebastian , Perilla-García Leidy Camila
Published: December 2024

Background: Hereditary Angioedema is an autosomal dominant disorder caused by a lack or decrease in the function of the C1 inhibitor. It is a rare disease with low prevalence. Treatment focuses on symptom relief and short- and long-term prevention of acute attacks.
Case report: 53-year-old male patient, with recurrent edema in the face, feet, scrotum, associated with abdominal pain since he was 20 years old. Patient has a history of hereditary angioedema in first-degree relatives of consanguinity. Laboratory tests showed low levels of plasma protein (antigenic), functional C1-INH and C4. The patient received several medical treatments. Given the recurrence of symptoms, prophylactic management with Lanadelumab was indicated. However, the patient presented erythema and induration at the application site with subsequent secondary generalized pruritus. For this reason, prophylaxis was suspended.
Conclusion: This case of hereditary angioedema type 1 presents the difficulty in the treatment and the relapse of the patient after trying various therapies, as well as the finding of the adverse effect presented to the prophylactic medication with Lanadelumab, which has been poorly documented in the literature medical worldwide.
Keywords: Hereditary angioedema type 1; Plasmatic protein; Prophylactic management; Adverse event; Lanadelumab.
Síndrome de DiGeorge con deleción 22q11.2 en un paciente de etnia Rarámuri
Authors: Casillas-Ituarte Aleida , Peña-Varela Claudia , Yamazaki-Nakashimada Marco Antonio , Gámez-González Luisa Berenise
Published: December 2024

Background: 22q11 deletion syndrome consists of a variable grouping of phenotypic features and immunological defects secondary to the loss of genetic material located in the 22q11.2 band. The 22q11 deletion spectrum encompasses different syndromes related to the same etiology and with overlapping anomalies, including DiGeorge syndrome, velocardiofacial syndrome, among others.
Case report: A 6-month-old male patient of indigenous Rarámuri ethnicity was referred to the Children's Specialty Hospital of Chihuahua due to severe malnutrition and respiratory distress. Upon admission, a grade V/VI holosystolic murmur and global neurodevelopmental delay were detected. He required endotracheal intubation and was admitted to the Pediatric Intensive Care Unit, where he had a long hospital stay. Some type of inborn error of immunity was suspected due to infectious processes, congenital heart disease, and evidence of facial dysmorphisms (malar hypoplasia, narrow palpebral fissures, tubular-like nose, and small mouth with high-arched palate), in addition to DiGeorge syndrome.
Conclusions: 22q11 deletion syndrome causes heterogeneous clinical manifestations, including multiple cardiac abnormalities and chronic diseases. In the Rarámuri population, there are currently no reports of this type of inborn error of immunity, so our patient exemplifies the need to intentionally search for these disorders, especially in those with severe infections, heart disease, and distinctive morphological characteristics. Disease detection programs are necessary, particularly in vulnerable populations.
Keywords: 22q11 deletion syndrome; DiGeorge syndrome; Inborn errors of immunity; Rarámuri population; Chihuahua.
Prevalencia y factores asociados con la sensibilidad a la metilisotiazolinona en individuos con sospecha de dermatitis alérgica por contacto: un estudio transversal
Authors: Belluco Paulo Eduardo Silva , Birolim Marcela Maria , Ferreira Maurício Domingues , Belluco Júllia Eduarda Feijó , Azevedo Fabíola da Silva Maciel , Pinheiro Bianca da Mota , Belluco Rosana Zabulon Feijó , Reis Carmelia Matos Santiago
Published: December 2024

Objetivo: Evaluar la prevalencia de sensibilidad a la metilisotiazolinona y los factores asociados en individuos con sospecha de dermatitis alérgica por contacto.
Métodos: Estudio transversal, llevado a cabo en pacientes con sospecha de dermatitis alérgica por contacto, a quienes se aplicaron pruebas de parche, incluida la metilisotiazolinona al 0.2%, atendidos en Brasilia/DF, Brasil, entre marzo de 2020 y marzo de 2022.
Resultados: Se registraron 286 pacientes con dermatitis alérgica por contacto. El 13.6% de los participantes fueron diagnosticados con dermatitis alérgica de contacto y sensibles a metilisotiazolinona. La edad media fue de 43.7 años y la mayoría fueron mujeres (71.8%). La duración media de la enfermedad fue de 60 meses. La localización más frecuente fueron las manos (76.9%) y los miembros superiores (33.3%). En el 97.4% la alergia a la metilisotiazolinona se consideró de relevancia actual. En el modelo multivariante, ser ama de casa incrementó la probabilidad de padecer sensibilidad a la metilisotiazolinona en 4.2% de los casos (IC95%: 1.36 – 13.5). Manifestar lesiones en diferentes sitios anatómicos también tuvo asociación significativa (OR: 2.84; IC95%: 1.17 – 6.86) de tener sensibilidad a la sustancia de ensayo.
Conclusión: Los hallazgos confirman la epidemia de alergia a la metilisotiazolinona. Refuerzan la necesidad de inclusión de esta sustancia aislada en las series de referencia brasileñas. Es importante reglamentar el uso de metilisotiazolinona en productos industriales y detergentes domésticos, como se hace con los cosméticos; por tanto, se requieren estudios adicionales, en otros centros, para confirmar estos resultados.
Palabras clave: Prevalencia; Metilisotiazolinona; Dermatitis por contacto; Alergia; Epidemiología; Detergentes; Productos industriales.
Growth and Yield of Two Tomato Plant Varieties in Dryland Areas with Agronomic Modification Treatments
Authors: Mahardhika Baiq Eliza Prizma , Jaya I Komang Damar , Sudirman  , Wirawan I Gede Putu Wirarama Wedashwara , Santoso Bambang Budi
Published: December 2024

The yield of tomato plants in dryland areas has been suboptimal due to environmental constraints such as poor soil health and high sunlight intensity. Appropriate agronomic modifications are necessary to improve crop yields while maintaining soil health. This study investigated the impact of various agronomic modification treatments on the growth and yield of tomato plants in dryland regions. The experiment was conducted in Gumantar Village, North Lombok Regency, during the dry season from June to August 2023. The agronomic modifications included a seaweed biochar treatment at a rate of 10 tons per hectare and 45% shading, with a control group that had no modifications. Three treatments were tested on two varieties of tomato plants: hybrid and local superior. The treatments were organized with four replications in a randomized complete block design with split plots, where agronomic modifications served as the main plots and the tomato varieties as the subplots. The results indicated that the interaction of agronomic modifications and plant varieties impacted the growth of tomato plants and various environmental factors. The hybrid variety under shading treatment exhibited the best growth. Additionally, this hybrid variety produced 59.6% more fruit than the local superior variety, yielding an average of 66 fruits and weighing 3.00 kg per plant. This study suggests that incorporating agronomic modifications, such as biochar treatment and selecting the appropriate variety, can enhance tomato yields in dryland areas.
Validity and Practicality Electronic Pocketbook-Based Google Sites for High School Level
Authors: Jannah Misbahul , Rijal Mujibul , Nasir Muhammad
Published: December 2024

This research addresses the limitations of textbook-centered learning resources, which hinder students' understanding of complex concepts and equations, particularly in the topics of sound and light waves. The study aims to develop, validate, and assess the practicality of an electronic pocketbook based on Google Sites for high school-level materials on sound and light waves. Employing the Research and Development (R&D) method, this study follows the Alessi and Trollip development model, consisting of Planning, Design, and Development phases. Expert validators in the fields of content, media, and language, along with feedback from 24 students and three teachers from Senior High School 9 Banda Aceh, were utilized to assess the pocketbook. Results show that the electronic pocketbook successfully completed all development stages and achieved high validity, with material validation at 95.29%, media validation at 91.90%, and language validation at 93.06%, all categorized as "very feasible". Additionally, both student and teacher evaluations confirmed the practicality of the pocketbook, with a score of 94.17%, also categorized as "very practical". The electronic pocketbook is thus deemed a highly valid and practical supplementary learning tool for both classroom and extracurricular use
THE ROLE OF WHISTLEBLOWING, CULTURE, AND ORGANIZATIONAL COMMITMENT IN FRAUD PREVENTION
Authors: Yuhanis Ladewi  , Muhammad Fahmi  , Fauziah Alfina Damayanti , Zuraidah Ida
Published: December 2024

This study aims to find out and analyze the role of whistleblowing culture, and organizational commitment in fraud prevention. The types of research used are descriptive and associative. The population used is 11 branch stores with a saturated sample of 85 respondents. This study uses primary and secondary data. The data collection methods are interviews, questionnaires, and documentation. To test the data, this research applies validity and reliability tests. The data analysis techniques used are descriptive statistics and inferential statistical analysis, namely classical assumption tests (normality test, multicollinearity test, and heteroscedasticity test) and multiple linear regression analysis, determination coefficient, and t-test. This study uses the analysis technique of the SPSS Version 25 data processing program. Based on the results processed, 85 respondents are all valid and reliable. The results of this study can be concluded partially (t-test) showing that whistleblowing, organizational culture, and organizational commitment have a significant effect on fraud prevention at PT Sumber Alfaria Trijaya Tbk in Plaju District.
 
Keywords     : Cheating Prevention, Organizational Commitment, Organizational Culture, Whistleblowing
Intercultural Communication Between Traders And Buyers In Padang Panjang Culinary Market
Authors: Roem Elva Ronaning , Istiyanto S.Bekti , Sarmiati Sarmiati , Vanisya Winda
Published: December 2024

The province of West Sumatra offers a variety of tourist attractions, one of which is the contemporary culinary scene in Padang Panjang. This city attracts visitors from various regions within West Sumatra as well as from outside the province. The diversity of culinary offerings, including both traditional and modern dishes, makes Padang Panjang a popular culinary destination. This research aims to explore tourists' perceptions of the night culinary market in Padang Panjang, which has become one of the city's main attractions. The study uses a qualitative approach to delve into the dynamics of communication between traders and customers at the market. Data was collected through direct observation, interviews with traders and visitors, and document analysis. The research findings show that the harmony of interactions at the culinary market is achieved through various communication strategies, including intercultural, interpersonal, and non-verbal communication. The study identifies two prominent communication patterns: the use of easily understood language and smiling as practical strategies to connect traders and customers from diverse backgrounds. Tourists' perceptions of the culinary market indicate that the food stalls offer high-quality food, which leaves them satisfied and eager to return.
The Dynamics of Family Communication among Working Mothers in the Digital Era
Authors: Satia Rahmawati Lusi , Hidayat Dasrun , Rina Nofha , Nurhadi Zikri Fachrul
Published: December 2024

In this modern age, most families have both parents working. Despite their professional responsibilities, mothers play a crucial role in the family’s health and well-being, particularly as the primary educators of their children. This research aims to analyze the experiences of working mothers regarding family communication dynamics through WhatsApp, focusing on the closeness between working mothers and their children. The study employs qualitative methods with a phenomenological approach to explore the shared experiences of individuals or groups with similar characteristics. The participants are working mothers aged 27 or older, with at least a diploma education, who actively use WhatsApp to communicate with their children and reside in Bandung. The research indicates that WhatsApp is a highly effective communication tool for working mothers to sustain family communication dynamics. It helps instill positive values, sympathy, and empathy, and is considered a primary necessity for maintaining a close relationship between working mothers and their children.
Disaster Communication among Flash Flood Victims in Garut Regency
Authors: Milyane Tita Melia , Djuwita Amalia , Parsono Slamet , Mukhlisiana Lusy
Published: December 2024

This study focuses on disaster communication among victims of flash floods on Friday night, July 15, 2022. According to data from the Regional Disaster Management Agency (BPBD), the severe rain caused 112 places to flood, 27 areas to experience landslides, and nine regions to experience floods and landslides simultaneously. This study aims to determine how the local government handles disaster communication and how victims of flash floods react to government-managed disaster relief efforts.  The theories used are public communication theory and the concept of disaster communication. The methodology used is qualitative, with data collection techniques through in-depth interviews with victims and local governments and literature reviews. The results showed that the government has tried to deal with the impact of flooding and communicate it through radio media, local newspapers, civil apparatus, and community empowerment and family welfare (PKK); however, after the flood was over, some residents chose to stay at the location for various reasons and considerations. In contrast, some other residents decided to occupy a new residence provided by the local government. The government also uses social media and WhatsApp groups to coordinate with related agencies and community elements.
Critical Discourse Analysis of the Indonesian Government in the VUCA Era
Authors: Putranto Algooth
Published: December 2024

The rapid changes of the times affect various aspects of human life globally. This condition is considered part of the conditions that occur in the Volatility, Uncertainty, Complexity, and Ambiguity (VUCA era). The VUCA era has also impacted people in Indonesia, especially in the economic sector, causing prices of basic necessities to keep rising. To manage the economic situation, the Indonesian government must adopt an effective public communication strategy to stabilize society. This research uses Stuart Hall's representation theory, which examines how language produces meaning in public communication. The aim is to analyze the government's communication strategy in responding to global economic and political uncertainty in the VUCA era. The study adopts a qualitative approach, utilizing critical discourse analysis by Norman Fairclough. The primary data comes from the Indonesian government's communications, specifically through the Presidential Secretariat's YouTube account, analyzing three selected videos. The findings indicate that President Joko Widodo's administration aims to shape public perception, reassuring citizens that the nation's economic uncertainty is manageable. This research highlights the importance of understanding the VUCA era and provides insights for the government to adopt appropriate communication strategies to guide public attitudes and behavior.
DESENVOLVIMENTO ECONÔMICO DE CARAGUATATUBA: O EFEITO DO RECEBIMENTO DE ROYALTIES NA EDUCAÇÃO ENTRE OS ANOS 2000 E 2023.
Authors: CARNIELLO MONICA FRANCHI , BUSSOLOTTI JULIANA MARCONDES , SOUZA MARIANA ARANHA DE
Published: December 2024

A Lei 9478 foi aprovada pelo governo brasileiro em 1997 e tem como responsabilidade o estabelecimento de novos parâmetros para a distribuição dos royalties do petróleo entre os municípios brasileiros