bluuebunny/crossref_metadata_2025 huggingface dataset:
Description of three new species of Automeris Hübner, 1819 from Colombia and Brazil (Lepidoptera, Saturniidae, Hemileucinae)
Authors: Decaëns Thibaud , Bénéluz Frédéric , Ballesteros-Mejia Liliana , Bonilla Diego , Rougerie Rodolphe
Published: April 2021

The Saturniidae is one of the most emblematic families of moths, comprising nearly 3000 species distributed globally. In this study, DNA barcode analysis and comparative morphology were combined to describe three new species within the genusAutomeris, which is the most diverse genus in the family.Automeris llanerosDecaëns, Rougerie & Bonilla,sp. nov.,Automeris minerosDecaëns, Rougerie & Bonilla,sp. nov., andAutomeris belemensisDecaëns, Rougerie & Bénéluz,sp. nov.are described from the Colombian Orinoco watershed, the Colombian Eastern Cordillera, and the area of endemism of Belém in the Brazilian Amazonia, respectively. They all belong to theAutomeris bilinea(Walker, 1855) species subgroup, which comprises a number of species that are sometimes difficult to distinguish from each other using morphology alone. Here, the description of these three new species is based on significant differences from their closest relatives, either in terms of wing patterns, genitalia, DNA barcodes or a combination of these features.
The first two blind troglobitic spiders of the genus Ochyrocera from caves in Floresta Nacional de Carajás, state of Pará, Brazil (Araneae, Ochyroceratidae)
Authors: Brescovit Antonio D. , Zampaulo Robson de A. , Cizauskas Igor
Published: April 2021

The first two anophthalmic species of spiders of the genus Ochyrocera Simon, 1892, are described for caves located in the iron formation of Floresta Nacional (FLONA) de Carajás in southeastern Pará State, Brazil. The caves are located in the municipalities of Parauapebas and Canaã dos Carajás, in the eastern portion of the Amazon Forest domain. Ochyrocera ritxocosp. nov. and O. ritxoosp. nov. are described based on males and females. The species have similar body characteristics with the total absence of eyes and complete depigmentation, characteristics that indicate possible evolution in subterranean environments , and thus are classified as troglobites. Each species is associated with a single geomorphological unit (mountain range), with Ochyrocera ritxocosp. nov. being restricted to caves of Serra Norte (North Mountain) and O. ritxoosp. nov. to caves of Serra Sul (South Mountain). Both species were collected in aphotic zones of the caves. Small and tangled webs of O. ritxocosp. nov. were observed under blocks of stone in the soil or in cracks of the walls.
Development and Validation of 3 Preliminary MRI Sacroiliac Joint Composite Structural Damage Scores in a 5-year Longitudinal Axial Spondyloarthritis Study
Authors: Wetterslev Marie , Østergaard Mikkel , Sørensen Inge J. , Weber Ulrich , Loft Anne G. , Kollerup Gina , Juul Lars , Thamsborg Gorm , Madsen Ole R. , Møller Jakob M. , Pedersen Susanne J.
Published: April 2021

Objective.

In axial spondyloarthritis (axSpA), sacroiliac joint (SIJ) erosion is often followed by fat metaplasia in an erosion cavity (backfill), and subsequently ankylosis. We aimed to combine the Spondyloarthritis Research Consortium of Canada (SPARCC) SIJ structural score for erosion, backfill, and ankylosis into 3 versions of a novel preliminary axSpA magnetic resonance imaging (MRI) SIJ Composite Structural Damage Score (CSDS) and to test these.

Methods.

Thirty-three patients with axSpA, followed for 5 years after initiation of tumor necrosis factor inhibitor, had MRIs of the SIJs at baseline, and yearly thereafter. Three versions of CSDS were calculated based on different weightings of erosion, backfill, and ankylosis: (1) equal weighting: CSDSequal = (erosion × 0.5) + backfill + ankylosis; (2) advanced stages weighting more: CSDSstepwise = (erosion × 1) + (backfill × 4) + (ankylosis × 6); and (3) advanced stages overruling earlier stages (“hierarchical”) with “<” meaning “overruled by”: CSDShierarchical = (erosion × 1) < (backfill × 4) < (ankylosis × 6).

Results.

At baseline, all CSDS correlated positively with SPARCC fat and ankylosis scores and modified New York radiography grading, and negatively with the Bath Ankylosing Spondylitis Disease Index and SPARCC SIJ inflammation scores. CSDSstepwise and CSDShierarchical (not CSDSequal) correlated positively with symptom duration and the Bath Ankylosing Spondylitis Metrology Index, and closer with SPARCC ankylosis score and modified New York radiography grading than CSDSequal. The adjusted annual progression rate for CSDSstepwise and CSDShierarchical (not CSDSequal) was higher the first year compared with fourth year (P = 0.04 and P = 0.01). Standardized response mean (baseline to Week 46) was moderate for CSDShierarchical (0.64) and CSDSstepwise (0.59) and small for CSDSequal (0.25).

Conclusion.

Particularly CSDSstepwise and CSDShierarchical showed construct validity and responsiveness, encouraging further validation in larger clinical trials. The potential clinical implication is assessment of SIJ damage progression by 1 composite score.
Effects of Denosumab in Japanese Patients With Rheumatoid Arthritis Treated With Conventional Antirheumatic Drugs: 36-month Extension of a Phase III Study
Authors: Tanaka Yoshiya , Takeuchi Tsutomu , Soen Satoshi , Yamanaka Hisashi , Yoneda Toshiyuki , Tanaka Sakae , Nitta Takaya , Okubo Naoki , Genant Harry K. , van der Heijde Désirée
Published: April 2021

Objective

To evaluate the safety and efficacy of long-term denosumab 60 mg every 6 months (Q6M) or every 3 months (Q3M) in patients with rheumatoid arthritis (RA).

Methods

This 12-month, randomized, double-blind, placebo-controlled, multicenter, phase III trial with an open-label extension period from 12 to 36 months (DESIRABLE) enrolled Japanese patients with RA treated with placebo (P) for 12 months followed by either denosumab Q6M (P/Q6M) or denosumab Q3M (P/Q3M) for 24 months; denosumab Q6M for 36 months (Q6M/Q6M); or denosumab Q3M for 36 months (Q3M/Q3M). Efficacy was assessed by van der Heijde modified total Sharp score (mTSS), bone erosion score (BES), and joint space narrowing (JSN) score.

Results

Long-term treatment better maintained mTSS and BES suppression in the P/Q3M and Q3M/Q3M vs P/Q6M and Q6M/Q6M groups; changes from baseline in total mTSS (standard error) at 36 months were 2.8 (0.4) and 1.7 (0.3) vs 3.0 (0.4) and 2.4 (0.3), respectively, and corresponding changes in BES were 1.3 (0.2) and 0.4 (0.2) vs 1.4 (0.2) and 1.1 (0.2), respectively. No JSN effect was observed. Bone mineral density consistently increased in all groups after denosumab initiation, regardless of concomitant glucocorticoid administration. Serum C-terminal telopeptide of type I collagen decreased rapidly at 1 month postdenosumab administration (in both the initial 12-month [Q3M and Q6M groups] and long-term treatment [P/Q3M and P/Q6M groups] phases). Adverse event incidence leading to study drug discontinuation was similar across treatment groups.

Conclusion

Denosumab treatment maintained inhibition of progression of joint destruction up to 36 months. Based on effects on BES progression, higher dosing frequency at an earlier treatment stage may be needed to optimize treatment. Denosumab was generally well tolerated. (ClinicalTrials.gov: NCT01973569).
Comparison of Men and Women With Axial Spondyloarthritis in the US-based Corrona Psoriatic Arthritis/Spondyloarthritis Registry
Authors: Mease Philip J. , McLean Robert R. , Dube Blessing , Liu Mei , Rebello Sabrina , Glynn Meghan , Yi Esther , Park Yujin , Ogdie Alexis
Published: April 2021

Objective

To compare patient characteristics and disease burden between men and women with axial spondyloarthritis (axSpA) in the US-based Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry.

Methods

Patients aged ≥ 18 years with axSpA enrolled in the Corrona PsA/SpA Registry between March 2013 and November 2018 who were not concurrently diagnosed with PsA were included. Patient demographics, clinical characteristics, disease activity, patient-reported symptoms, work productivity, and treatment history at enrollment were compared between men and women, using t tests or Wilcoxon rank-sum tests for continuous variables and chi-square or Fisher exact tests for categorical variables.

Results

Of 498 patients with axSpA and available sex information, 307 (61.6%) were men and 191 (38.4%) were women. Compared with men, women had higher disease activity as measured by Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Functional Index, and physician global assessment, and had higher tender/swollen joint counts and enthesitis scores (all P ≤ 0.01). Women also had worse patient-reported symptoms (pain, fatigue, Health Assessment Questionnaire for the Spondyloarthropathies, and EuroQol visual analogue scale; all P < 0.05), had greater work and activity impairment, and were less likely to work full time than men. Prior conventional synthetic disease-modifying antirheumatic drug and prednisone use was more common in women than in men (both P < 0.05). Additionally, women were more likely to have diagnoses of depression and fibromyalgia (both P < 0.01).

Conclusion

In this US registry of patients with axSpA, women had higher overall disease burden and more peripheral manifestations than men. Improved awareness of sex differences in the presentation of axSpA may aid physicians in earlier identification and improved disease management.
Accueillir les situations d’abus sexuel incestueux
Authors: Collas Cyril
Published: April 2021

Lorsqu’une personne subit un abus sexuel incestueux, elle contacte une expérience d’une violence inassimilable en soi. Elle s’immobilise de manière à ne pas sentir le trauma. Pour aider à se remobiliser, le thérapeute devra la rejoindre dans son expérience de chaos, sans se faire engloutir lui-même ou sans être pris dans la reproduction induite qui tend à le configurer comme abuseur. À cette occasion, l’alliance thérapeutique permettra au client de retourner au cœur de l’intime blessé.
La posture psynodique
Authors: Brissaud Frédéric
Published: April 2021

La posture psynodique est une attitude d’accompagnement présentant six caractéristiques essentielles : imprévisibilité, ouverture, respect, doute, humilité et asymétrie. Radicalement différente de la posture finaliste, caractérisée par les notions d’objectif, de planification, d’évaluation et d’efficacité, la distinction psynodique/finaliste explicite une ligne de démarcation des pratiques réelles. Mise à jour par l’observation de gestalt-thérapeutes, il est probable que des pratiques de praticiens se réclamant d’autres méthodes présentent, elles aussi, ces six caractéristiques essentielles.
Le fil d’Antigone
Authors: Petit Mélanie
Published: April 2021

Hegel qualifiait la pièce Antigone de Sophocle de tragédie la plus parfaite. Peut-on, encore aujourd’hui, malgré les critiques ultérieures, soutenir cette idée et la fonder ? Si la perfection de cette tragédie tient dans le tissage de conflits que Sophocle construit, nous devrons d’abord effiler chaque conflit, pour ensuite affilier chaque position à ce qui la fonde, et suivre enfin le déroulé tragique du fil d’Antigone.
Gouvernance d’une association villageoise d’épargne et de crédit : entre intentionnalité et spécificité
Authors: Alidou Djaoudath
Published: April 2021

Cet article traite de la gouvernance des associations villageoises d’épargne et de crédit (Avec), à partir de l’étude d’une structure de ce type située au nord du Bénin. L’auteure s’intéresse particulièrement aux mécanismes de contrôle en présence ainsi qu’à leurs interactions. Elle s’appuie pour cela sur la grille de lecture de Charreaux (1997) adaptée aux associations, avec une approche orientée sur les parties prenantes empruntant les principes et les valeurs de la coopération des théories du contrat psychologique et social. L’analyse montre que les mécanismes spontanés et spécifiques (confiance, pression par les pairs, etc.) sont les plus importants. Ces associations sont non seulement des alternatives viables, mais aussi des catalyseurs pour le renforcement du capital social, le leadership des femmes et le développement communautaire économique et social.
Les grands travaux du PAEE d’Oran : esthétique urbaine et fabrique de la ville par le logement
Authors: Taibi Sofiane
Published: April 2021

La production du logement social en France des années 1930 correspond à une époque où une nouvelle génération de penseurs de la ville, les urbanistes, élaborent pour la première fois des Plans d’Aménagement d’Embellissement et d’Extension (PAEE) pour les agglomérations françaises et qui vont traverser la méditerranée. Oran, ville dont la première extension se fait pendant l’application de la loi Cornudet et de la politique des Habitations à Bon Marché (HBM), constitue un bon exemple de cette orientation. Nous présentons dans cette contribution une analyse urbanistique des travaux de réalisation du PAEE d’Oran et de l’expérience des HBM de Choupot. L’objectif ici est de vérifier l’hypothèse suivante : la première extension d’Oran s’est faite dans un contexte favorable à l’expérimentation, visant l’homogénéisation de la ville et sa continuité urbaine à travers la conception et la réalisation du logement et son prolongement de l’habitat. Classification JEL  : R21, R38, R52.
L’entrepreneuriat des femmes dans l’économie sociale et solidaire : une synthèse des points de vue des entrepreneures
Authors: Cauwet Sophie
Published: April 2021

Les données chiffrées indiquent que, parmi les salariés de l’économie sociale et solidaire, la part des femmes est majoritaire. Pourtant, plus l’échelle des responsabilités augmente, moins les femmes y sont représentées. Se pose donc la question des motivations de celles qui entreprennent dans l’économie sociale et solidaire. Est-ce le fruit du « hasard » ? Un choix assumé ? Une voie volontairement empruntée ? Au sein des structures qu’elles dirigent, ces entrepreneures agissent et réagissent sur un terrain mouvant. Elles « mènent la barque » par une dynamique collective en conciliant les impératifs liés à l’équilibre économique mis au service de l’utilité sociale. Elles cherchent à mettre en œuvre des stratégies et des logiques d’action pour garder le cap et atteindre un but. Quelles sont-elles ? L’aventure est faite de hauts et de bas, mais elle fait grandir. Les entrepreneures peuvent compter pour cela sur des ressources, internes et externes. Elles peuvent également compter sur des compétences qu’elles mettent au service de l’entreprise, et/ou qu’elles développent avec l’expérience. Ici, différentes entrepreneures se livrent, et témoignent.
La fabrique du consensus autour du « gaz de couche de charbon » en France : analyse « archéologique » des discours d’appui à un projet extractif
Authors: Stein Marieke
Published: April 2021

L’article vise à comprendre et à décrire les phénomènes discursifs qui expliquent qu’un projet d’extraction de Coal Bed Methane (un hydrocarbure voisin du gaz de schiste) ne soit que peu contesté, en France, alors que dans les pays où il est déjà exploité, cet hydrocarbure suscite de vives controverses. En effet, les discours (politiques, institutionnels, médiatiques, parfois même scientifiques…) qui circulent sur ce sujet dans l’espace public français véhiculent une vision unanimement favorable du projet extractif. La méthode ici proposée est celle d’une « archéologie » des discours qui circulent dans les différentes arènes en interaction. Cette analyse « archéologique » se caractérise par une attention particulière à des dynamiques d’élaboration et de transformation des discours dans le temps, et vise à découvrir, sous les énoncés qui véhiculent aujourd’hui une représentation univoque de l’activité extractive, les énoncés originels. La description des processus qui permettent l’envahissement des discours publics par les seuls énoncés doxiques mis en circulation par l’entreprise gazière à l’origine du projet, grâce à une analyse sémio-argumentative de la quasi-totalité des discours qui circulent autour de cette extraction dans les espaces publics légitimés, éclaire la « fabrique du consensus » par une analyse en diachronie des discours en interaction (discours entrepreneurial, militant, politique, institutionnel, de légitimation et oppositionnel…), de leurs trajectoires et de leurs métamorphoses.
X-Ray Diffraction Analysis by Williamson-Hall, Size-Strain, Halder-Wagner Plot Methods for Ni Doped CdS Nanoparticles
Authors: Vinjamuri Krishna Bharath , Viswanadha Sashank , Basireddy Hymavathi , Borra Rajesh Kumar
Published: April 2021

Cadmium sulfide (CdS) doped with different concentrations of Ni (2, 4, 6, 8, and 10 %) nanoparticles have been synthesized by chemical co-precipitation method. X-ray diffraction (XRD) studies confirm the crystalline nature of Ni doped CdS nanoparticles had a hexagonal wurtzite structure. Williamson-Hall (W–H), Size-Strain Plot (SSP), and Halder-Wagner (H–W) methods have been used to investigate the average particle size, lattice strain, stress, and energy density from the XRD peak broadening analysis. In W–H method, the models of uniform deformation, uniform deformation stress, and uniform deformation energy density have been implemented to determine the elastic parameters.
Modelling of Flow Behaviour and Rheological Properties of M2 Steel in Semisolid State
Authors: Simlandi Sudip , Barman Nilkanta
Published: April 2021

The present study develops a model to investigate time dependent behaviours of M2 steel in semisolid state during step-change in shear rate. The Couette flow of the semisolid material between two parallel plates is considered. The flow field is presented by momentum conservation equation. The non-Newtoniun behaviour of the semisolid material is expressed by the Herschel-Bulkley model. The agglomeration and de-agglomeration phenomena of the suspended particles in semisolid state under shear are represented introducing a time dependent structural parameter. The proposed model fitted well with existing work in a wide range of shear rates and could predict the flow and apparent viscosity of semisolid M2 steel. Finally, the work involves prediction of the flow field, rate of strain and apparent viscosity of the semisolid material under transient condition. It is observed that the time dependent viscosity is highly non-linear during step-change in shear rate. It is noticed that the structural parameter decreases as the shear rate is increased. Whereas, the apparent viscosity decreases with increasing shear rate but shows an undulation and after that gradually rises to a higher steady value as the plate velocity decreases suddenly.
Effect of Oxygen Flow Rate on the Characteristics of RF Sputtered ZnO Thin Films
Authors: Parhana Pathan , Lakshmaiah M.V.
Published: April 2021

Zinc Oxide (ZnO) thin films were deposited on glass substrate by radio frequency (RF)reactive magnetron sputtering technique at variable Oxygen flow rates while Argon flow rates waskept constant. The effect of oxygen flow rate on structural, electrical, optical properties of nanostructured ZnO thin films were investigated by X-ray diffractometer, scanning eletron microscopy(SEM), Hall effect measurements and UV-Visible spectrophotometer. X-ray diffraction (XRD) datareveals films are polycrystalline hexagonal structure with (002) peak as a preferred orientation andcrystallite size was found to be in range12 nm-16 nm.The electrical resistivity of films decreasesfrom 10-1 Ω-cm to 10-2 Ω-cm. All deposited ZnO thin films shows high transmittance above 95% inthe visible range 360 nm-800 nm. The optical band gap and refractive indices have been calculatedusing UV-Vis transmission spectra. Oxygen gas flow rates found to have large impact onoptoelectronic properties of ZnO films.
Behaviour of Heat Treated Aluminium Alloy under Hardness Test
Authors: Pranav Domadala , Sivaram Sruthi , Nadarajan Mukesh , Selokar Ashish
Published: April 2021

Currently, Aluminium (Al) 6061 material is used in various industrial application and Automobile sector. Al 6061 gives good formability and excellent mechanical properties. This paper is mainly focused on the behaviour of the heat-treated aluminium alloy-6061 under the various test such as hardness test, impact test and other industrial applications. Based on the outcomes of Heat treatment, the quality of the Aluminium alloy-6061 is also compared with that of Aluminium alloy-5083, 6063. Hence, this paper helps in future research, which is based on the behaviour of the Heat-treated aluminium alloy under Hardness test.
Graphene-based Composites for the Thermal Decomposition of Energetic Materials
Authors: Liu Ya Hao , Zheng Jian , Yu Gui Bo , Qia Jing , Xu Quan Qun , Zhang Chun Ming , Zhang Xiao
Published: April 2021

Owing to its remarkable mechanical, electrical and thermal properties, graphene has been a hot area of composites research in the past decade, including the field of energetic materials. Graphene has been widely applied in enhancing the physical properties of energetic materials, such as solid composite propellants. Through the way of adding different forms of graphene into the matrix of solid propellants, their thermal decomposition performance can be effectively improved. In this paper, we reviewed the status and challenges of the application of graphene in the thermal decomposition of composite solid propellant. Moreover, the main preparation methods and material structures of graphene are reviewed. We can conclude that graphene and its derivatives can enhance the catalytic effect remarkably, which can be attributed to the large specific surface area of graphene that makes the uniformly dispersed catalyst particles and the more catalyst active sites. Meanwhile, graphene possesses the high thermal conductivity, making the rapider heat diffusion, which can promote the decomposition reactions of the energetic components in solid propellants. Graphene and catalyst work synergistically in their thermal decomposition. More than this, the main methods to improve the thermal decomposition of energetic components of composite propellants and their effects on decomposition temperature reduction are systematically summarized, respectively.
The Sintering and Electrical Properties of La0.5Sr0.5Co0.96Ni0.04O3-δ Ceramics with B2O3- CuO Addition
Authors: Lu Yong Cheng , Li Yuan Xun , Peng Rui , Chen Da Ming , Yang Qing Hui , Zhang Shi Jun
Published: April 2021

The performance of adding 0–3 wt% B2O3-CuO as a sintering aid to lower the sintering temperature of La0.5Sr0.5Co0.96Ni0.04O3-δ (LSCN) was investigated through solid-state reaction method. Results of linear shrinkage curve, bulk density, and microstructure indicated that BCu addition could promote the sintering process and enhance the densification of LSCN ceramics. With the increase of BCu content, low absolute value of TCR could be achieved, while the conductivity was deteriorated obviously. For LSCN ceramics sintered at 950 °C, the bulk density, conductivity, and TCR were worse than those sintered at higher temperatures. Consequently, the BCu-doped LSCN ceramics might not suitable for the application in the field of LTCC.
Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging
Authors: Moudra Alena , Niederlova Veronika , Novotny Jiri , Schmiedova Lucie , Kubovciak Jan , Matejkova Tereza , Drobek Ales , Pribikova Michaela , Stopkova Romana , Cizkova Dagmar , Neuwirth Ales , Michalik Juraj , Krizova Katerina , Hudcovic Tomas , Kolar Michal , Kozakova Hana , Kreisinger Jakub , Stopka Pavel , Stepanek Ondrej
Published: April 2021

Ag-inexperienced memory-like T (AIMT) cells are functionally unique T cells, representing one of the two largest subsets of murine CD8+ T cells. However, differences between laboratory inbred strains, insufficient data from germ-free mice, a complete lack of data from feral mice, and an unclear relationship between AIMT cells formation during aging represent major barriers for better understanding of their biology. We performed a thorough characterization of AIMT cells from mice of different genetic background, age, and hygienic status by flow cytometry and multiomics approaches, including analyses of gene expression, TCR repertoire, and microbial colonization. Our data showed that AIMT cells are steadily present in mice, independent of their genetic background and hygienic status. Despite differences in their gene expression profiles, young and aged AIMT cells originate from identical clones. We identified that CD122 discriminates two major subsets of AIMT cells in a strain-independent manner. Whereas thymic CD122LOW AIMT cells (innate memory) prevail only in young animals with high thymic IL-4 production, peripheral CD122HIGH AIMT cells (virtual memory) dominate in aged mice. Cohousing with feral mice changed the bacterial colonization of laboratory strains but had only minimal effects on the CD8+ T cell compartment, including AIMT cells.
The Influence of Reminder Book to Adherence of Heart Failure Patients in Malang City
Authors: Hany Alfrina , Fadlila Rizqa , Lydia Endah Panca
Published: April 2021

Background

Non-adherence to the recommended therapy causes patients with heart failure to experience recurrence of the disease. Reminder book on therapy adherence is very useful, because it assists in monitoring adherence to therapy carried out by patients while at home. Therefore, this study aims to determine the effect of the existence of a reminder book on adherence to therapy among patients with heart failure in a private hospital in Malang.

Design and methods

A pre-experiment design with one-group pre and posttest was used. The respondents were 18 patients that received counseling on the management of heart failure therapy while at home and were given a reminder book. Furthermore, the modified MMAS-8 scale was the study instrument used to measure adherence.

Result

The results showed that most respondents were above the age of 65 with a treatment duration of 1 to 5 years. It was discovered that most of the respondents had never received information about heart failure therapy. Data analysis which was carried out using the Wilcoxon test with a p-value of 0.001, showed that there was a significant difference between respondents’ compliance before and after being given a reminder book.

Conclusions

From this study, it was concluded that providing a reminder book has an effect on therapeutic adherence in patients with heart failure. Researchers recommend that hospitals should make use of this reminder as a tool to control or supervise outpatient therapy.
The Effectiveness of Home-Based Nursing Intervention in the Elderly with Recurrent Diabetic Foot Ulcers: A Case Report
Authors: Wuri Kartika Annisa , Widyatuti Widyatuti , Rekawati Etty
Published: April 2021

Background

Inadequate glycemic control usually leads to peripheral neuropathy, vasculopathy, and foot deformities that leads to diabetic foot ulcer (DFU), and a 10-years history of diabetes and inadequate self-management increases the risk of reoccurring DFU. A home-based intervention program, which includes Diabetes Self-Management Education (DSME) and wound care is the most likely approach, to engage families and overcoming the barriers in self-care management. The aim of this study is to provide an overview on the effectiveness of home-based nursing intervention in the elderly patients with reoccurring diabetic foot ulcers.

Design and method

In this study, a case study approach was used that presented a case related to self-management and wound care in elderly patients with reoccurring DFU. The intervention was carried out by the community health nurses for eight weeks with home visit.

Results

Significant changes were reported in diabetes selfmanagement practices, blood glucose level, and wound healing. The Diabetes Self-Management Questionnaire (DSMQ) score increased from 5.62 to 8.,54 and the Summary of Diabetes Self- Care Activities (SDSCA) score increased from 3.2 to 6. The Bates Jansen Examination score decreased from 24 and 26 to 17 and 14 in six weeks.

Conclusions

The results confirm that family-based interventions program are effective in improving glycemic control and wound healing. Community nursing is believed to prevent an increase in self-management behavior to prevent recurring DFU and maintain a healthy life-style about diabetes self-management education.
High-Fructose Diet Initially Promotes Increased Aortic Wall Thickness, Liver Steatosis, and Cardiac Histopathology Deterioration, but Does Not Increase Body Fat Index
Authors: Handayani Dian , Febrianingsih Erlinda , Desi Kurniawati Adelya , Kusumastuty Inggita , Nurmalitasari Shafira , Widyanto Rahma Micho , Oktaviani Diah Novida , Maghfirotun Innayah Alma , Sulistyowati Etik
Published: April 2021

Background

Dietary fats and fructose have been responsible for inducing obesity and body tissues damage due to the consequence of metabolic syndrome through several mechanisms. The body fat index (BFI) is one of the anthropometric measures used to detect obesity in rats. This study aims to examine the correlation between high-fat high-fructose diet and liver steatosis cell count, early atherosclerosis characteristics, and body fat index (BFI) in Sprague Dawley rats.

Design and methods

This was an experimental design using 2 groups of 12-weeks-old Sprague Dawley (SD) rats. The control group received a standard diet and tap water beverages for 17 weeks. The intervention group was fed with high-fat diet from modified AIN 93-M and additional 30% fructose drink. We analyzed the foam cell count, aortic wall thickness, cardiac histopathology, and liver steatosis cell count after the sacrifice process.

Results

The rats in the intervention group had a higher aortic wall thickness, liver steatosis, and foam cell count (+125%, p<0.01; +317%, p<0.01 and +165%, p<0.01 respectively) compared to the control group. The intervention group also showed higher mononuclear inflammatory and hypertrophic cell count. A significant positive correlation was found between dietary fructose with premature atherosclerosis by increasing foam cell count (r=0.66) and aortic wall thickness (r=0.68). In addition, 30% dietary fructose increased liver steatosis (r=0.69) and mononuclear inflammatory cardiac cell count (r=0.61). Interestingly, the intervention had no effect on the body fat index (p>0.5; r=0.13).

Conclusions

Dietary fat and fructose consumption for 17 weeks promotes atherosclerosis, liver steatosis, and cardiac histopathology alteration without increasing BFI.
The Needs of Traumatic Brain Injury Survivors' Caregivers and the Implication Required during the Covid-19 Pandemic: Public Health Issues
Authors: Othman Hamidah , Ludin Salizar Mohamed , Saidi Sanisah , Awang Mohamed Saufi
Published: April 2021

Background

Traumatic brain injury (TBI) survivors require attention and dependence from their primary caregiver. This is because TBI is a defect that affects both the psychological and physical functions of the victim. Caregivers play an essential role in providing the adequate care victims need to adjust to the new problems they may experience due to their condition, as family members alone may not be able to provide for their needs. In particular, TBI caregivers may face specific challenges when assisting their patients in handling unexpected changes to their daily routines. Therefore, this quantitative study aims to explore the needs of caregivers, their coping mechanisms towards stressful and traumatic circumstances, and how they provide care to their loved ones during the COVID-19 pandemic.

Design and Methods

It was conducted with ten caregivers of individuals suffering from traumatic brain injury, that were selected using a theoretical sampling method. Data were obtained using a semi-structured interview guide, which helped the caregivers provide their responses. Meanwhile, data analysis was performed using the NVIVO analysis software.

Results

The results showed that there were, three significant themes namely, (a) Support needed, (b) the information need for care, and (c) developing self-resilience. The results also showed that caregivers really need support from the various parties, and the participants lack information on specific care techniques for the severe traumatic brain injury (TBI) survivors. Conclusions: In conclusion, caregivers require approval and seek more useful information to provide excellent care to their loved ones. Being aware of the caregiver's needs would enable them to offer improved customized care.
Factors Related to Implementation of Nursing Care Ethical Principles in Indonesia
Authors: Ilkafah Ilkafah , Mei Tyas Anestesia Pangestu , Haryanto Joni
Published: April 2021

Background

The implementation of ethical principles is crucial in carrying out nursing care, since it is part of the 12 basic competencies, that should be possessed by a nurse. This study aims to analyse the factors associated with the implementation of nurses’ ethical principles.

Design and methods

This study used a quantitative research design, with a cross-sectional approach. The participants consisted of 389 nurses, working in the medical ward of the hospitals, in Indonesia. Data were analysed using the bivariate analysis, t-test, ANOVA and multiple linear regression test.

Results

There were no significant relationships between the demographic factors and the ethical behaviour. There was a relationship between caring behaviour and the application of ethical principles (p=0.000, and a correlation coefficient of 0.602).

Conclusion

Nurse ethical behaviour was improved, by increasing their caring attitude.
Exploring the relationship between nurses’ communication satisfaction and patient safety culture
Authors: Wieke Noviyanti Linda , Ahsan Ahsan , Sudartya Tita Sefti
Published: April 2021

Background: Patient safety culture is associated with the values, attitudes, competencies and behaviors that support the safe conduct of individual or group activities in hospitals and other health organizations. Safety culture is influenced by various factors, one of which is communication, which plays a significant role in health services. Therefore, this study aims to analyze the relationship between nurse communication satisfaction and the quality of patient safety culture in hospitals. Design and Methods: This is a cross-sectional design with the proportional random sampling method used to data from 51 nurses, which was analyzed using the Spearman rank test. The majority of the nurses were female, between 20 – 30 years old, with 1-5 years working experience.Results: The results showed a significant relationship between nurse communication satisfaction and the quality of patient safety culture. Furthermore, the higher the nurses' level of communication satisfaction, the better the applied quality of patient safety culture (r = 0.338).ConclusionS: Nurse communication satisfaction affects the provision of effective health care, with the ability to create good cooperative relationships and foster trust between professions in order to improve the quality of service delivery and patient safety.
Correlation between Nurse-Patient Interaction and Readiness to Care for Post-Treated Heart Failure Patients in the Intensive Care Room Malang, Indonesia
Authors: Hany Alfrina , Vatmasari Ratih Arum
Published: April 2021

Background

The number of people with heart failure significantly increases every year. Therefore, this study aims to determine the nurse-patient interaction capable of providing adequate care to post-treated heart failure patients in intensive care rooms.

Design and methods

This is a cross-sectional study with the consecutive sampling method used to obtain data from 100 posttreatment heart failure patients in intensive care rooms. PPIQ (Patient Professional Interaction Questionnaire) was used to measure nurse-patient interactions, while Self-care readiness was determined using the SCHFI (Self-Care Heart Failure Instrument).

Result

The result showed that there is a significant correlation between nurse-patient interactions and their readiness to care for post-treated heart failure patients in intensive care with a Pearson correlation value of 0.000 (p=0.05). Furthermore, both variables have a moderate and positive correlation strength and with a correlation coefficient value of 0.557.

Conclusions

The yearly increase in the number of re-hospitalized patients in hospitals can be reduced with an increase in nursepatient interaction. This enables patients to have the ability to take proper care of themselves after leaving the hospital.
Is Instant Porridge with a High Calcium Content Based on Moringa Oleifera as an Alternative Baby Food to Prevent Stunting in Indonesia?
Authors: Katmawanti Septa , Supriyadi  , Mariroh Fariha
Published: April 2021

Background

According to WHO, stunting is a state of heightfor- age index below minus two standard deviation. However, the condition could be prevented by giving suitable complementary food to babies and toddlers. Moringa leaves are rich in vitamins A, C, B6, as well as calcium, potassium, iron, as well as protein, and are therefore used as complementary foods for breast milk, in baby feeding.

Design and methods

Instant porridge was developed using three formulas. Each formula comprised Moringa leaf flour (5, 6 and 7 grams each) combined with 30 grams of oatmeal powder, 40 grams of powdered formula, 10 grams of refined sugar, and 5 grams of banana flour.

Results

Based on the organoleptic test, Formula 3 (created with 5 grams of Moringa leaf flour) was discovered to be the best. The organoleptic evaluation panel consisted of 3 trained and 30 untrained participants, while the statistical results showed the parameters of colour, texture, and taste, have no significant effect on panellists’ acceptance.

Conclusions

The flavour parameter has a significant effect on panellists’ acceptance, with a p-value <0.05.
Knowledge, Awareness and Dietary Practice on Urolithiasis among General Population in Kuantan, Pahang, Malaysia: Preliminary Findings
Authors: Sowtali Siti Noorkhairina , Arifin Siti Roshaidai Mohd , Nazli Nor Syawanidamia , Shukri Nor Azwani Binti Mohd , Khattak Muhammad Muzaffar Ali Khan , Ab Rashid Islah Munjih , Binti Muhamad Suhana , Adzali Fatin Noraliah
Published: April 2021

Background

To date, no studies have been published at evaluating the level of knowledge, awareness and practice of dietary, particularly regarding to urolithiasis in patients or the general population. This study aims to provide basic information on the level of knowledge, awareness and dietary practice among general population in Kuantan, Pahang.

Design and methods

The respondents (n=30) were conveniently recruited within 10 kilometers radius of Kuantan city. The data were obtained using semi-guided administered questionnaires, which consists of four parts: socio-demographic data, lifestyle and clinical history (Part A); attitude and awareness on dietary practice regarding urolithiasis (Part B); food frequency questionnaire on urolithiasis (Part C) and level of knowledge on urolithiasis (Part D).

Results

Majority of the respondents were women (70%), Malay (83.3%), mean age of 33.97 (±9.27), married (63.3%), completed higher education level (60%), working with government sector (33.3%) and have fixed monthly income (53.3%). Some of them had hypertension (n=4), diabetes (n=1), gout (n=1) and intestinal problem (n=1). Majority (80%) claimed having no family history of urolithiasis, consumed alcohol (10%), exercise with average frequency 2-3 times/week (46.7%) and heard about urolithiasis from healthcare worker (46.7%). The respondents’ awareness about urolithiasis is considered to be good [81.23 (±9.98)] but having poor knowledge score [2.70 (±1.149)]. Majority preferred whole meal bread, white rice, chicken meat, mackerel fish, chicken egg, apple, carrot, mustard leave and fresh milk in daily intake. Lesser plain water intake than standard requirement was noticed among respondents. Seasoning powder was commonly used for seasoning.

Conclusions

Generally, the general population of Kuantan, Pahang was aware of urolithiasis disease but needed more information on dietary aspect in terms of knowledge and food choice.
Ultrasound-guided assessment of gastric residual volume in patients receiving three types of clear fluids
Authors: Doctor Jeson Rajan , Chandan Pramila , Shetty Nitin , Gala Kunal , Ranganathan Priya
Published: April 2021

Background and Aims:

Ultrasonography (USG) is used to evaluate gastric residual volume (GRV); however, this technique may have inter-assessor variability. This study aimed to measure GRV in three groups of fasted patients 2 h after they received 200 mL of water, clear apple juice or apple-flavoured oral rehydration solution (ORS) and to determine inter-assessor reliability of USG-guided GRV measurement.

Methods:

We randomised 90 adult patients planned for elective cancer surgery, with no risk factors for delayed gastric emptying, to receive 200 mL of water, clear apple juice or apple-flavoured ORS after overnight fasting. Two hours later, two blinded assessors (a trained anaesthesiologist and a radiologist) independently determined USG-guided GRV. The primary outcome was GRV measured by the radiologist. The secondary outcome was inter-assessor correlation and agreement in GRV measurements.

Results:

There was no statistically significant difference in median GRV between groups (apple-flavoured ORS 74.8 mL, apple juice 63.7 mL, and water 62.1 mL, P = 0.11). We found poor correlation between measurements of radiologist and anaesthesiologist (Intra-class correlation coefficient 0.3, 95% confidence intervals 0.09 to 0.48, P value 0.002). The average (mean) bias was 5.4 mL (standard deviation 42.3 mL) and the 95% limits of agreement were -79.2 ml to +90 ml.

Conclusion:

Patients receiving 200 mL of water, clear apple juice or apple-flavoured ORS had comparable GRV after 2 h. There was poor correlation and agreement between GRV measurements of different assessors, indicating that more training may be required for anaesthesiologists to attain proficiency in the quantitative assessment of GRV.
Anaesthetic implications and transfusion practices in ABO incompatible living donor liver transplantation
Authors: Balakrishnan Sindhu , Kumar Lakshmi , Daniel Divya , Surendran Sudhindran
Published: April 2021

ABO incompatible liver transplants (ABOi LT) are considered as a life-saving option when compatible donor grafts are unavailable. Fourteen adults (right lobe graft) and three children (left lateral segment/lobe) who underwent ABOi LT from living donors between 2011 and 20 period were analysed for transfusions and desensitisation protocols. All recipients received packed red blood cells (PRBC) of their own group. AB plasma that does not contain any antibody was transfused in eight patients and donor group plasma in others. None of the patients developed transfusion related complications. Plasmapheresis and rituximab/bortezumab desensitisation was practised in 11 patients, only rituximab in four, only plasmapheresis in one, and no treatment in a 1 year child. Rejection was manifest in three patients while nine patients developed infections and sepsis. A working knowledge of the blood and product transfusions in ABOi LT is crucial for the anaesthesiologist. Perioperative management and impact of desensitisation protocol are discussed.
Study comparing different airway assessment tests in predicting difficult laryngoscopy
Authors: Panjiar Pratibha , Bhat Kharat Mohammed , Yousuf Irshad , Kochhar Anjali , Ralli Tanya
Published: April 2021

Background and Aims:

Limited studies are available comparing diagnostic accuracy of various airway predictors in geriatric patients. We conducted this study with primary aim to evaluate and validate the predictive value of 'standard airway predictors' like modified Mallampati test, thyromental distance (TMD), sternomental distance, neck movement (NM), mouth opening (MO), dentition and 'new airway predictors' like upper lip bite test (ULBT), ratio of height to thyromental distance and thyromental height test (TMHT) for predicting difficult laryngoscopy in geriatric patients.

Methods:

This prospective, observational study was conducted on 140 patients above 65 years of age of either sex, scheduled for elective surgery under general anaesthesia requiring endotracheal intubation. The age, weight, height, body mass index (BMI) and airway parameters were recorded. The laryngoscopic view was assessed by modified Cormack-Lehane scale. Standard formulae were used to calculate validity indexes.

Results:

The incidence of difficult larygoscopy found in our study was 25%. The mean age of our study population was 69.37 ± 4.23 years. TMD exhibited the highest sensitivity (80%) and negative predictive value (NPV) (91.86%) as compared to other studied airway predictors. The positive predictive value (PPV) of ULBT was 100%. Moreover, ULBT exhibited highest accuracy (82.14%) and odds ratio (86.88) and high specificity (91.30%) for predicting difficult laryngoscopy in geriatric patients. NM and TMHT also exhibited high accuracy (77.85%, 77.14%) and PPV (59.09%, 52.94%).

Conclusions:

TMD and ULBT both showed good predictive value in diagnosing difficult laryngoscopy in geriatric patients. Furthermore, NM and TMHT also exhibited higher diagnostic accuracy in predicting difficult airway in these patients.
Correlation between radial and femoral arterial blood pressure during reperfusion in living donor liver transplantation
Authors: Thomas Manu , Kumar Lakshmi , Jain Priyanka , Sarma Chitra , Paul Shabala , Surendran Sudhindran
Published: April 2021

Background and Aims:

Accurate blood pressure measurements are the mainstay for the efficient management of abrupt cardiovascular changes during reperfusion in liver transplant. We sought to compare the femoral and radial pressures during reperfusion and at T1:baseline, T2: 1 h in dissection: T3:portosystemic shunt, T4:reperfusion, T5: at bile duct anastomosis.

Methods:

A retrospective study was performed amongst 102 adult patients who underwent R lobe living donor liver transplantation. Mean arterial pressure (MAP) and systolic arterial pressure (SAP) at 10 s intervals at reperfusion and at five fixed time points were compared by intraclass correlation coefficient (ICC) and limits of agreement by Bland–Altman statistics.

Results:

MAP by both routes had a good correlation at all time points during reperfusion (overall ICC: 0.946 [0.938, 0.949]) in comparison with SAP (overall ICC: 0.650 [0.6128, 0.684]). At the lowest reperfusion pressure (reperfusion point), MAP showed high levels of agreements (ICC: 0.833 [0.761, 0.885]), whereas SAP showed only a poor level of agreement (ICC 0.343 [0.153, 0.508]). The Bland–Altman analysis for MAP showed a bias of 7.18 (5.94) mmHg and limits of agreement of − 4.5 mmHg to + 18.8 mmHg and for SAP a bias of 25.2 (22.04) mmHg and limits of agreement of − 18.0 mmHg to + 68.4 mmHg at the reperfusion point. The incidence of post-reperfusion syndrome (PRS) was 52.94% by femoral and 57.84% by radial routes.

Conclusions:

Radial MAP correlated well with femoral MAP during reperfusion and at predefined time points and can be used interchangeably for intraoperative monitoring. A high incidence of PRS was noted by our technique of measurement.