bluuebunny/crossref_metadata_2025 huggingface dataset:
Formation of porous Ga oxide with high-aspect-ratio nanoholes by anodizing single Ga crystal
Authors: Kondo Toshiaki
Published: July 2023

I developed a simple crystal growth process to obtain a single Ga crystal. The crystal orientation of a Ga plate could be controlled by a crystal growth process using a seed Ga crystal. By anodizing a [100]-direction highly oriented Ga plate, I realized the formation of a highly ordered array of high-aspect-ratio straight nanoholes. It was observed that the nanohole growth direction depends on the crystal orientation of a Ga plate. To date, this dependence has yet to be observed in materials other than porous Ga oxide obtained by an anodization process. The present fabrication process is expected to be applied to the fabrication of various functional devices requiring a porous Ga oxide with high-aspect-ratio straight nanoholes, such as hydrogen formation devices and functional filters.
Comparing kinematic asymmetry and lateral step-down test scores in healthy, chronic ankle instability, and patellofemoral pain syndrome female basketball players: a cross-sectional study
Authors: Emamvirdi Mahsa , Hosseinzadeh Mahdi , Letafatkar Amir , Thomas Abbey C. , Dos’Santos Thomas , Smania Nicola , Rossettini Giacomo
Published: July 2023

We aimed to understand whether ankle dorsiflexion range of motion (ROM) and dynamic knee valgus (DKV) kinematic inter-limb asymmetries would be associated with the Lateral Step-Down Test (LSD) in basketball players with chronic ankle instability (CAI), patellofemoral pain (PFP) and healthy controls (HC). An observational cross-sectional study with a between-subject design was employed. Female basketball athletes with CAI (n = 20), PFP (n = 20) and HC (n = 20) were recruited. Ankle dorsiflexion-ROM, DKV angle during a single-limb squat, and LSD quality were measured bilaterally. The Asymmetry index (ASI) was calculated to identify between-limb percentage imbalances. The correlation matrix between the tasks was calculated. Ankle dorsiflexion-ROM was less in the CAI and PFP than in the HC group regardless of limb (p < 0.001). DKV angle was greater in the CAI and PFP than in the HC group bilaterally (p < 0.001). LSDs were similar between the PFP and CAI groups (p = 0.698) but worse than the HC group (p = 0.001). The ASI showed asymmetry across all tasks (p < 0.001), with the greatest asymmetry for the DKV angle. The correlation matrix between tasks on both limbs was significant (p < 0.05). Our findings suggest significant asymmetries in ankle dorsiflexion-ROM and frontal plane knee control are present in female basketball athletes with CAI and PFP, and thus, highlights need to evaluate and reduce limb asymmetries in these populations.
ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1
Authors: Takahashi Sayuri , Takada Ichiro , Hashimoto Kenichi , Yokoyama Atsushi , Nakagawa Tohru , Makishima Makoto , Kume Haruki
Published: July 2023

Molecular targeted therapy using poly (ADP-ribose) polymerase inhibitors has improved survival in patients with castration-resistant prostate cancer (CRPC). However, this approach is only effective in patients with specific genetic mutations, and additional drug discovery targeting epigenetic modulators is required. Here, we evaluated the involvement of the transcriptional coregulator ESS2 in prostate cancer. ESS2-knockdown PC3 cells dramatically inhibited proliferation in tumor xenografts in nude mice. Microarray analysis revealed that ESS2 regulated mRNA levels of chromodomain helicase DNA binding protein 1 (CHD1)-related genes and other cancer-related genes, such as PPAR-γ, WNT5A, and TGF-β, in prostate cancer. ESS2 knockdown reduced nuclear factor (NF)-κB/CHD1 recruitment and histone H3K36me3 levels on the promoters of target genes (TNF and CCL2). In addition, we found that the transcriptional activities of NF-κB, NFAT and SMAD2/3 were enhanced by ESS2. Tamoxifen-inducible Ess2-knockout mice showed delayed prostate development with hypoplasia and disruption of luminal cells in the ventral prostate. Overall, these findings identified ESS2 acts as a transcriptional coregulator in prostate cancer and ESS2 can be novel epigenetic therapeutic target for CRPC.
Non-invasive enhancement of intracortical solute clearance using transcranial focused ultrasound
Authors: Yoo Seung-Schik , Kim Evgenii , Kowsari Kavin , Van Reet Jared , Kim Hyun-Chul , Yoon Kyungho
Published: July 2023

Transport of interstitial fluid and solutes plays a critical role in clearing metabolic waste from the brain. Transcranial application of focused ultrasound (FUS) has been shown to promote localized cerebrospinal fluid solute uptake into the brain parenchyma; however, its effects on the transport and clearance of interstitial solutes remain unknown. We demonstrate that pulsed application of low-intensity FUS to the rat brain enhances the transport of intracortically injected fluorescent tracers (ovalbumin and high molecular-weight dextran), yielding greater parenchymal tracer volume distribution compared to the unsonicated control group (ovalbumin by 40.1% and dextran by 34.6%). Furthermore, FUS promoted the drainage of injected interstitial ovalbumin to both superficial and deep cervical lymph nodes (cLNs) ipsilateral to sonication, with 78.3% higher drainage observed in the superficial cLNs compared to the non-sonicated hemisphere. The application of FUS increased the level of solute transport visible from the dorsal brain surface, with ~ 43% greater area and ~ 19% higher fluorescence intensity than the unsonicated group, especially in the pial surface ipsilateral to sonication. The sonication did not elicit tissue-level neuronal excitation, measured by an electroencephalogram, nor did it alter the molecular weight of the tracers. These findings suggest that nonthermal transcranial FUS can enhance advective transport of interstitial solutes and their subsequent removal in a completely non-invasive fashion, offering its potential non-pharmacological utility in facilitating clearance of waste from the brain.
Investigation of Brønsted acidity in zeolites through adsorbates with diverse proton affinities
Authors: Trachta Michal , Bludský Ota , Vaculík Jan , Bulánek Roman , Rubeš Miroslav
Published: July 2023

Understanding the adsorption behavior of base probes in aluminosilicates and its relationship to the intrinsic acidity of Brønsted acid sites (BAS) is essential for the catalytic applications of these materials. In this study, we investigated the adsorption properties of base probe molecules with varying proton affinities (acetonitrile, acetone, formamide, and ammonia) within six different aluminosilicate frameworks (FAU, CHA, IFR, MOR, FER, and TON). An important objective was to propose a robust criterion for evaluating the intrinsic BAS acidity (i.e., state of BAS deprotonation). Based on the bond order conservation principle, the changes in the covalent bond between the aluminum and oxygen carrying the proton provide a good description of the BAS deprotonation state. The ammonia and formamide adsorption cause BAS deprotonation and cannot be used to assess intrinsic BAS acidity. The transition from ion-pair formation, specifically conjugated acid/base interaction, in formamide to strong hydrogen bonding in acetone occurs within a narrow range of base proton affinities (812–822 kJ mol−1). The adsorption of acetonitrile results in the formation of hydrogen-bonded complexes, which exhibit a deprotonation state that follows a similar trend to the deprotonation induced by acetone. This allows for a semi-quantitative comparison of the acidity strengths of BAS within and between the different aluminosilicate frameworks.
A comprehensive model for predicting the development of defense system of Capparis spinosa L.: a novel approach to assess the physiological indices
Authors: Afzali Sayed Fakhreddin , Sadeghi Hossein , Taban Azin
Published: July 2023

Capparisspinosa L. (caper) is a halophytic plant that grows in semi-arid or arid environments. The current study used an integrated experimental and computational approach to investigate the network of inter-correlated effective variables on the activity of antioxidant enzymes, proline, and photosynthetic pigments in stressed caper. To investigate the possible relationships among intercorrelated variables and understand the possible mechanisms, predictive regression modelling, principal component analysis (PCA), Pearson's correlation, and path analysis were implemented. PCA successfully discerned different salt ratio- and drought-specific effects in data in the current study, and treatments with higher growth indices are easily recognizable. Different salt ratios did not have a significant effect on the activity of four antioxidant enzymes, proline and photosynthesis pigments content of caper. While at the mean level, the activity of four antioxidant enzymes of SOD, POD, CAT, and APX significantly increased under drought stress by 54.0%, 71.2%, 79.4%, and 117.6%, respectively, compared to 100% FC. The drought stress also significantly increased the content of carotemoid (29.3%) and proline (by 117.7%). Predictive equation models with highly significant R2 were developed for the estimation of antioxidant enzyme activity and proline content (> 0.94) as well as pigments (> 0.58) were developed. Path analysis studies revealed that proline is the most important regressor in four antioxidant enzyme activities, while leaf tissue density was the most effective variable in the case of chlorophylls. Furthermore, the network of intercorrelated variables demonstrated a close relationship between caper's antioxidant defence system, pigments, and morphological parameters under stress conditions. The findings of this study will be a useful guide to caper producers as well as plant ecophysiological researchers.
A ultrasonic nomogram of quantitative parameters for diagnosing breast cancer
Authors: Wang Cong , Che Ying
Published: July 2023

This study aimed to develop a nomogram through the collection of quantitative ultrasound parameters to predict breast cancer. From March 2021 to September 2022, a total of 313 breast tumors were included with pathological results. Through collecting quantitative ultrasound parameters of breast tumors and multivariate regression analysis, a nomogram was developed. The diagnostic performances, calibration and clinical usefulness of the nomogram for predicting breast cancer were assessed. A total of 182 benign and 131 malignant breast tumors were included in this study. The nomogram indicated excellent predictive properties with an AUC of 0.934, sensitivity of 0.881, specificity of 0.848, PPV of 0.795 and NPV of 0.841. The calibration curve showed the predicted values are basically consistent with the actual observed values. The optimum cut-off for the nomogram was 0.310 for predicting cancer. The decision curve analysis results corroborated good clinical usefulness. The model including BI-RADS score, SWE and VI is potentially useful for predicting breast cancer.
Present geothermal field of the Santos Basin, Brazil
Authors: Zuo Guoping , Wang Hongping , Lan Lei , Zhang Yonggang , Zuo Yinhui , Yang Liu , Wang Chaofeng , Pang Xu , Song Xu , Yang Meihua
Published: July 2023

The Santos Basin, located in the southeastern waters of Brazil, is a passive continental margin basin with the most abundant deepwater petroleum resources in the world discovered to date. However, few studies have been conducted on the present geothermal fields of the Santos Basin, which severely restricts the oil and gas resource evaluation of the basin. This study first utilizes 35 temperature data from 16 post-salt drilling wells and 370 temperature data from 31 pre-salt drilling wells to calculate the post-salt and pre-salt geothermal gradients and terrestrial heat flows in the Santos Basin. Then, the basin simulation software BasinMod 1D is used to quantitatively evaluate the impacts of salt rock sedimentation on the present geothermal fields and the maturity of pre-salt hydrocarbon source rocks. The results demonstrate that the present post-salt geothermal gradient in the Santos Basin is 2.20–3.97 °C/100 m, with an average value of 2.99 °C /100 m, and the post-salt terrestrial heat flow is 54.00–97.32 mW/m2, with an average value of 73.36 mW/m2, while the present pre-salt geothermal gradient is 2.21–2.95 °C/100 m, with an average value of 2.53 °C/100 m, and the pre-salt terrestrial heat flow is 61.85–82.59 mW/m2, with an average value of 70.69 mW/m2. These values are characteristic of a low-temperature geothermal field in a zone with a stable structure. The sedimentation of the salt rock causes a decrease in the temperature of the pre-salt strata, which inhibits pre-salt hydrocarbon source rock maturity, with an inhibition rate of up to 1.32%. The inhibition degree decreases with increasing salt rock thickness. At the same time, the salt rock thickness is positively correlated with the present surface heat flow. The unique distribution of the salt rock and related salt structures lead to present terrestrial heat flow differences among different structural units in the basin. This study is of great significance for evaluating and exploring the pre-salt oil and gas resources in the Santos Basin.
Influence of sulfide on diazotrophic growth of the methanogen Methanococcus maripaludis and its implications for the origin of nitrogenase
Authors: Payne Devon , Spietz Rachel L. , Newell Dennis L. , Dijkstra Paul , Boyd Eric S.
Published: July 2023

Methanogens inhabit euxinic (sulfide-rich) or ferruginous (iron-rich) environments that promote the precipitation of transition metals as metal sulfides, such as pyrite, reducing metal or sulfur availability. Such environments have been common throughout Earth’s history raising the question as to how anaerobes obtain(ed) these elements for the synthesis of enzyme cofactors. Here, we show a methanogen can synthesize molybdenum nitrogenase metallocofactors from pyrite as the source of iron and sulfur, enabling nitrogen fixation. Pyrite-grown, nitrogen-fixing cells grow faster and require 25-fold less molybdenum than cells grown under euxinic conditions. Growth yields are 3 to 8 times higher in cultures grown under ferruginous relative to euxinic conditions. Physiological, transcriptomic, and geochemical data indicate these observations are due to sulfide-promoted metal limitation, in particular molybdenum. These findings suggest that molybdenum nitrogenase may have originated in a ferruginous environment that titrated sulfide to form pyrite, facilitating the availability of sufficient iron, sulfur, and molybdenum for cofactor biosynthesis.
Comparative analysis of multifaceted neural effects associated with varying endogenous cognitive load
Authors: Pei Leisi , Northoff Georg , Ouyang Guang
Published: July 2023

Contemporary neuroscience has firmly established that mental state variation concurs with changes in neural dynamic activity in a complex way that a one-to-one mapping cannot describe. To explore the scenario of the multifaceted changes in neural dynamics associated with simple mental state variation, we took cognitive load – a common cognitive manipulation in psychology – as a venue to characterize how multiple neural dynamic features are simultaneously altered by the manipulation and how their sensitivity differs. Electroencephalogram was collected from 152 participants performing stimulus-free tasks with different demands. The results show that task demand alters wide-ranging neural dynamic features, including band-specific oscillations across broad frequency bands, scale-free dynamics, and cross-frequency phase-amplitude coupling. The scale-free dynamics outperformed others in indexing cognitive load variation. This study demonstrates a complex relationship between cognitive dynamics and neural dynamics, which points to a necessity to integrate multifaceted neural dynamic features when studying mind-brain relationship in the future.
Selective emergence of photoluminescence at telecommunication wavelengths from cyclic perfluoroalkylated carbon nanotubes
Authors: Maeda Yutaka , Suzuki Yasuhiro , Konno Yui , Zhao Pei , Kikuchi Nobuhiro , Yamada Michio , Mitsuishi Masaya , Dao Anh T. N. , Kasai Hitoshi , Ehara Masahiro
Published: July 2023

Chemical functionalisation of semiconducting single-walled carbon nanotubes (SWNTs) can tune their local band gaps to induce near-infrared (NIR) photoluminescence (PL). However, tuning the PL to telecommunication wavelengths (>1300 nm) remains challenging. The selective emergence of NIR PL at the longest emission wavelength of 1320 nm was successfully achieved in (6,5) SWNTs via cyclic perfluoroalkylation. Chiral separation of the functionalised SWNTs showed that this functionalisation was also effective in SWNTs with five different chiral angles. The local band gap modulation mechanism was also studied using density functional theory calculations, which suggested the effects of the addenda and addition positions on the emergence of the longest-wavelength PL. These findings increase our understanding of the functionalised SWNT structure and methods for controlling the local band gap, which will contribute to the development and application of NIR light-emitting materials with widely extended emission and excitation wavelengths.
Periodic module rejuvenation provides early market entry for circular all-perovskite tandem photovoltaic technologies
Authors: Tian Xueyu , Roose Bart , Stranks Samuel D. , You Fengqi
Published: July 2023

This work unveils periodic module rejuvenation as a new strategy to bring online the next-generation of perovskite tandem photovoltaic technologies earlier using experimental investigation and life cycle assessment modeling as an integrated tool.
Immune homeostasis modulation by hydrogel-guided delivery systems: a tool for accelerated bone regeneration
Authors: Mi Bobin , Xiong Yuan , Zha Kangkang , Cao Faqi , Zhou Wu , Abbaszadeh Samin , Ouyang Lizhi , Liao Yuheng , Hu Weixian , Dai Guandong , Zhao Zhiming , Feng Qian , Shahbazi Mohammad-Ali , Liu Guohui
Published: July 2023

This review underscores the importance of immune homeostasis in bone regeneration, presents developments in hydrogel-based delivery systems for local immunomodulation that accelerate bone repair, and discusses the challenges of clinical translation.
Metal–organic framework-derived Cu nanoparticle binder-free monolithic electrodes with multiple support structures for electrocatalytic nitrate reduction to ammonia
Authors: Wang Yingying , Cao Yue , Hai Yan , Wang Xinyan , Su Senda , Ding Wenming , Liu Zhenyu , Li Xiaoman , Luo Min
Published: July 2023

The Cu-BTC-Cu effectively overcame the weaknesses of unsatisfactory ammonia yield, enormous amounts of nitrite as a byproduct, and the poor stability of Cu-based catalysts.
In-modified Sn-MOFs with high catalytic performance in formate electrosynthesis from aqueous carbon dioxide
Authors: Yan Jiaying , Wang Xuanyu , Ning Fanghua , Yi Jin , Liu Yuyu , Wu Kai
Published: July 2023

The introduction of In greatly improves the catalytic performance of Sn-MOFs for CO2 electrochemical reduction.
Temperature symmetry breaking and properties of lead-free organic–inorganic hybrids: bismuth(iii) iodide and antimony(iii) iodide: (S(CH3)3)3[Bi2I9] and (S(CH3)3)3[Sb2I9]
Authors: Szklarz Przemysław , Gągor Anna , Jakubas Ryszard , Medycki Wojciech , Bator Grażyna
Published: July 2023

Two novel lead-free ferroelastic materials, (S(CH3)3)3[Sb2I9] and (S(CH3)3)3[Bi2I9], which exhibit reach sequences of phase transitions and reveal semiconducting properties, have been synthesized.
Aryl C–H bond functionalization with diphenyldiazomethane induced by rare-earth metal alkyl complexes
Authors: Guo Dianjun , Rajeshkumar Thayalan , Zhu Shan , Yuan Qingbing , Hong Dongjing , Zhou Shuangliu , Zhu Xiancui , Maron Laurent , Wang Shaowu
Published: July 2023

A simple and efficient synthetic method for aryl C–H bond functionalization with diphenyldiazomethane for the construction of Caryl–Nhydrazinato bonds under mild conditions was disclosed.
New application of a periodic mesoporous nanocrystal silicon–silica composite for hyperlipidemia
Authors: Lu Wenbin , Jin Hao , Ding Jiandong , Zhang Yahao , Wu Yong
Published: July 2023

The integration of the properties of silicon nano crystallinity with silica mesoporosity provides a wealth of new opportunities for emerging biomedicine.
Construction of mPt/ICG-αA nanoparticles with enhanced phototherapeutic activities for multidrug-resistant bacterial eradication and wound healing
Authors: Li Lei , Zhu Guoqing , Xu Wencheng , Wang Man , Xie Yulin , Bao Zixian , Qi Manlin , Gao Minghong , Li Chunxia
Published: July 2023

Novel composite nanoparticles mPt/ICG-αA, which combine catalase-like, photodynamic, photothermal, and α-amylase hydrolysis properties, have been developed for multidrug-resistant bacterial eradication and wound healing.
Catalytic nickel silicide as an alternative to noble metals in metal-assisted chemical etching of silicon
Authors: Kim Kyunghwan , Choi Sunhae , Bong Haekyun , Lee Hanglim , Kim Minyoung , Oh Jungwoo
Published: July 2023

First-time demonstration of the catalytic characteristics of a NiSi alloy as an alternative to noble metals for metal-assisted chemical etching.
The emergence and advancement of Tsuji–Trost reaction triggered carbon monoxide recognition and bioimaging
Authors: Biswas Bidisha , Deka Snata , Mondal Prosenjit , Ghosh Subrata
Published: July 2023

The present article comprehensively reviews the remarkable developments made in the area of optical materials for recognition and imaging of carbon monoxide following Tsuji–Trost reaction.
Synthesis of modified bile acids via palladium-catalyzed C(sp3)–H (hetero)arylation
Authors: Borade Somnath Arjun , Naharwal Sushma , Bhambri Himanshi , Mandal Sanjay K. , Bajaj Kiran , Chitkara Deepak , Sakhuja Rajeev
Published: July 2023

A Pd(ii)-catalyzed strategy for the (hetero)arylation of unactivated C(sp3)–H bonds in bile acids with aryl and heteroaryl iodides to prepare modified bile acids under solvent-free conditions.
Correction: Mechanochemical asymmetric three-component Mannich reaction involving unreactive arylamines
Authors: Hu Xiaoyun , Li Kang , Yu Huiting
Published: July 2023

Correction for ‘Mechanochemical asymmetric three-component Mannich reaction involving unreactive arylamines’ by Xiaoyun Hu et al., Org. Biomol. Chem., 2023, https://doi.org/10.1039/d3ob00954h.
Recent advances in nanotechnology for combating Alzheimer's disease
Authors: Hu Chuan , Wu Baoyu , Wu Yihan , Shi Mingyi , Ma Jiaqi , Gao Huile , Zhang Jinming
Published: July 2023

This review provides an overview of recent advances in nanotechnology that are achieved to improve the therapeutic efficiency for treating Alzheimer's disease.
Visible-light-mediated photocatalytic sequential N-arylation: an eco-friendly synthetic route to unsymmetrical diarylamines and the imatinib drug
Authors: Sana Sravani , Dastari Sowmya , Reddy Dannarm Srinivas , Tokala Ramya , Sathish Manda , Sonti Rajesh , Shankaraiah Nagula
Published: July 2023

A sustainable photoredox-mediated protocol for the construction of unsymmetrical diarylamines using a Cu/Ru catalytic system has been successfully devised with a wide substrate scope and good yields.
Correction: Surface modification of graphene with functionalized carbenes and their applications in the sensing of toxic gases: a DFT study
Authors: Aldulaijan Sarah , Ajeebi Afnan M. , Jedidi Abdesslem , Messaoudi Sabri , Raouafi Noureddine , Dhouib Adnene
Published: July 2023

Correction for ‘Surface modification of graphene with functionalized carbenes and their applications in the sensing of toxic gases: a DFT study’ by Sarah Aldulaijan et al., RSC Adv., 2023, 13, 19607–19616, https://doi.org/10.1039/D3RA02557H.
A novel process towards the industrial realization of large-scale oxymethylene dimethyl ether production – COMET
Authors: Mantei Franz , Schwarz Christian , Elwalily Ali , Fuchs Florian , Pounder Andrew , Stein Hendrik , Kraume Matthias , Salem Ouda
Published: July 2023

The novel COMET process for the production of OME3-5 from MeOH and FA(aq.) solves the challenging H2O management using a reactive distillation column. The main process units are state-of-the-art and were experimentally demonstrated.
Effect of airflow rate and drainage on the properties of 2D smectic liquid crystal foams
Authors: Fu Changshuo , Lin Hongjie , Nere Rachel N. , Gharbi Mohamed Amine
Published: July 2023

Investigating the experimental parameters affecting the properties of 2D smectic liquid crystal foams.
Effect of microstructure evolution on the mechanical behavior of magneto-active elastomers with different matrix stiffness
Authors: Roghani Mehran , Romeis Dirk , Saphiannikova Marina
Published: July 2023

We present an effective model, that in agreement with experiments, predicts a huge increase in the stiffness of soft MAEs, due to the formation of columnar structures from magnetized particles.
Research progress in fluorinated carbon sources and the discharge mechanism for Li/CFxprimary batteries
Authors: Gao Meiting , Cai Danmin , Luo Sifei , Yang Yuhan , Xie Yong , Zhu Licai , Yuan Zhongzhi
Published: July 2023

Lithium/fluorinated carbon (Li/CFx) primary batteries are still receiving extensive attention in particularly the study of CFxcathodes has made great progress in recent years with the discovery of new carbon sources.
Metal-free covalent organic frameworks containing precise heteroatoms for electrocatalytic oxygen reduction reaction
Authors: Li Jiali , Jia Ji , Suo Jinquan , Li Cuiyan , Wang Zhiwei , Li Hui , Valtchev Valentin , Qiu Shilun , Liu Xiaoming , Fang Qianrong
Published: July 2023

A series of BTT-COFs were successfully synthesized and showed high ORR catalytic activity. Particularly, the JUC-616 electrocatalyst is the best of the metal-and pyrolysis free COF based electrocatalysts reported to date.
Design and fabrication of intracellular therapeutic cargo delivery systems based on nanomaterials: current status and future perspectives
Authors: Ma Hong , Xing Fei , Zhou Yuxi , Yu Peiyun , Luo Rong , Xu Jiawei , Xiang Zhou , Rommens Pol Maria , Duan Xin , Ritz Ulrike
Published: July 2023

Intracellular cargo delivery is an important strategy for deciphering cell function, directing cell fate, and reprogramming cell behavior.
Application of nanotechnology in bladder cancer diagnosis and therapeutic drug delivery
Authors: Li Hang-zhuo , Zhu Jian , Weng Guo-jun , Li Jian-jun , Li Lei , Zhao Jun-wu
Published: July 2023

Application of nanomaterials in the diagnosis and treatment of BC.
Crystalline solid retains memory of anisotropy in precursor liquid crystalline phase
Authors: Bagchi Kushal , Emeršič Tadej , Wang Zhongyang , Chen Wen , Kim Mincheol , Eom Christopher , Jiang Zhang , Strzalka Joseph , de Pablo Juan J. , Nealey Paul F.
Published: July 2023

Crystallization from an aligned discotic liquid crystal results in biaxially textured crystals of an organic semiconductor.
Quantum transport and fractional hall effect in Moiré correlated/anticorrelated interface channels
Authors: Shayeganfar Farzaneh , Ramazani Ali
Published: July 2023

The energy-resolved transmission of twisted circular (anticorrelated) nanoribbons depends on twisted angles, where the hybridization of local fermion momenta as f-orbitals and itinerant conduction electrons as c-orbitals play an important role.
Parent Experiences of Undertaking Therapy for Cleft Palate Speech Disorders Following In-Depth Training
Authors: Sell Debbie , O'Rourke Claire , Sweeney Triona
Published: July 2023

Purpose:

This study aimed to investigate the experiences of parents of children with cleft-related speech sound disorders who had received in-depth training, following which they were the active agents of intervention, supported by a specialist cleft therapist.

Method:

All parents (
N
= 23) who had participated in the parent training arm of a previously published two-phase, two-center, 12-week randomized controlled trial in Dublin, Ireland, and London, United Kingdom, were invited to participate in the study. Eighteen families consented, and in three families, both parents took part, resulting in 21 participants. Sixteen parents participated in one of the four focus groups conducted in each location after each phase of the trial. Three families (
n
= 5) participated in semistructured telephone interviews. Focus groups and interviews were conducted by professionals who were not involved in the trial.

Results:

Focus groups and interviews were analyzed using a thematic analysis. Four main themes with subthemes emerged: growth of parents (knowledge, skills, insights, and emotional experiences), undertaking parent-led articulation therapy (bespoke program, flexibility, challenges, supervision/support), changes in the children (speech, confidence, behavior), and the future (ongoing therapy and recommendation of this approach).

Conclusions:

This study answered the research question, detailing how in-depth training and parent-led therapist-supervised interventions are acceptable to parents. Speech/language pathologists should encourage trained parents to take a direct role in intervention with their children, with supervision and support from therapists. Future research should investigate the experiences of parents with lower educational attainment, identify parent factors that supported implementation, and report children's experiences.
A Gaia astrometric view of the open clusters Pleiades, Praesepe, and Blanco 1
Authors: Alfonso Jeison , García-Varela Alejandro
Published: July 2023

Context. Nearby open clusters, such as Pleiades, Praesepe, and Blanco 1, have been extensively studied due to their proximity to the Sun. The Gaia data provide the opportunity to investigate these clusters, because they contain valuable astrometric and photometric information that can be used to update their kinematic and stellar properties.

Aims. Our goal is to carry out a star membership study in these nearby open clusters by employing an astrometric model with proper motions (PMs) and an unsupervised clustering machine learning algorithm that uses positions, PMs, and parallaxes. The star members are selected from the cross-matching between both methods. Once we know the members, we investigate the spatial distributions of these clusters and estimate their distances, ages, and metallicities.

Methods. We used the Gaia DR3 catalogue to determine star members using two approaches: a classical Bayesian model and the unsupervised machine learning algorithm DBSCAN. For star members, we built radial density profiles and spatial distributions, and computed the King parameters. The ages and metallicities were estimated using the BASE-9 Bayesian software.

Results. We identified 958, 744, and 488 star members for Pleiades, Praesepe, and Blanco 1, respectively. We corrected the distances and built the spatial distributions, finding that Praesepe and Blanco 1 have elongated shape structures. The distances, ages, and metallicities obtained were consistent with those reported in the literature.

Conclusions. We obtained catalogues of star members, and updated kinematic and stellar parameters for these open clusters. We find that the PMs model can find a similar number of members to the unsupervised clustering algorithm when the cluster population forms an overdensity in the vector point diagram. This allows us to select an adequate size of the PMs region with which to run these methods. Our analysis found stars that are being directed towards the outskirts of Praesepe and Blanco 1, which exhibit elongated shapes. These stars have high membership probabilities and similar PMs to those within the tidal radius.
Preliminary Evaluation of Crustal Medium Parameters in Western China
Authors: Zheng Xingqun , Tao Zhengru
Published: July 2023

The establishment of attenuation relation of ground motion is always an important research content in engineering earthquake field. In seismology-based ground motion attenuation relationship and ground motion simulation using the stochastic method, regional parameters are necessary. These parameters involve stress drop Δσ, two segmentation points R1 and R2 of the geometric spreading item, Q0 and η of the inelastic attenuation item and the near-surface high-frequency decay parameter κ0, which reflect the regional crustal medium and site characteristics and have little relation with the earthquake size. In this paper, we take Sichuan, Yunnan and Xinjiang regions in western China as examples and we inverse the parameters for each region by micro-genetic algorithm. The inversion ranges of crustal media parameters in the three regions were determined respectively. Finally, we get the inversion results of every parameters and find that the parameters of the three regions have a great difference.
Application of Forward Modeling in Putaohua Oilfield
Authors: Guan Peixin
Published: July 2023

Putaohua Oilfield is bounded by the large fault on the south side of Pu A1 Well. It is divided into Pubei and Punan development zones on the plane. It is an oilfield that has been developed by water injection for more than 30 years. With the increase of development time, the water content of oil wells increases rapidly, and the oil production of the oilfield decreases rapidly,In order to realize the study of petroleum geological potential in this area, find out the favorable target area for well layout, and effectively improve the drilling success rate,first of all, we need to do forward modeling for the study area to lay a solid foundation for subsequent research.

This paper analyzes the change characteristics of seismic wave frequency attenuation attribute in reservoir oil and gas, and applies it to the study of reservoir oil and gas prediction in Putaohua Oilfield.
Design of a One-Stop Platform for on-Demand Supply of Biomass Pellet Fuel in China
Authors: Qiang Jinglun , Zhou Yuguang , Yu Yaohong , Deng Yun , Fu Yongkun , Wu Wei
Published: July 2023

China is currently rich in biomass resources, and is in a period of energy transition, the development of biomass is the general trend. However, the development of biomass pellet fuel is still immature and faces many obstacles. At this stage, the sales of biomass pellet fuel has problems such as unclear parameters or insufficient coverage. Therefore, it is proposed to build a one-stop platform to promote the development of biomass fuel industry by using modern means to widely collect information on pellet fuel, calculate the reduction potential of pellet fuel, and build an online platform to reduce the information difference. This paper constructs a database by obtaining a large amount of information on biomass fuels through questionnaires, telephone consultations and access to information on websites. Based on the established database, Jupyter was used to analyze the number of fuel types, the provincial contribution, the fuel price distribution and the calorific value distribution. Among them, Guangdong, Shandong, Jiangsu, Hebei and other large grain provinces have the highest contribution of biomass fuels; most of the fuel types are mainly wood fuels, with wood chips, pine and redwood being the main types; the calorific value of fuels is mainly concentrated in the range of 3800-4600kcal/kg; and the price of fuels is mainly concentrated in the range of 600-1000 RMB. In order to reflect the cleanliness of biomass fuels, the article accounts for the carbon emissions of biomass fuel substitutes at different stages of their life cycle, with the aim of providing a reference for users. Eventually a one-stop platform for supply and demand of biomass fuel was established based on a database and carbon accounting methodology. The idea is to import the database into the backend of the WeChat app for retrieval, display it on the front end and sort it according to the user's choice, and give an estimate of emission reductions based on the user's purchase volume and transport distance.
Simultaneous Determination of Mixed Heavy Metal Ions Cr (III) and Co (II) in Wastewater by Cloud Point Extraction Dual Wavelength Spectrophotometry
Authors: Liu Hongmei , Xie Jun , Qian Hongming
Published: July 2023

Using cloud point extraction technology and the principle of absorbance addition in multi-component system, the mixed metal ions Cr (III) and Co (II) in industrial wastewater were enriched and determined at pH 5.0 and 50℃, using ammonium pyrrolidine dithiocarbamate (APDC) as complexing agent and Triton X-114 as extractant. The results indicate that the contents of Cr (III) and Co (II) can be calculated using a simultaneous equation system. The detection limits for Cr (III) and Co (II) are 0.74 ng/ml and 2.12 ng/ml, respectively. The recovery rates are 95.3% -104.0% and 96.9% -103.5%, respectively. This method has the characteristics of high accuracy, good repeatability, and fast detection speed, and has good practical value.
Study on Preparation and Properties of La0.6Sr0.4Co0.2Fe0.8O3-Δ-mGd0.2Ce0.8O2 (M=0,30,40 and 50) Composite Cathode
Authors: Qin Minghan
Published: July 2023

Solid Oxide Fuel Cells (SOFCs) can convert chemical energy into electrical energy, with high energy conversion rate, safe operation, no pollutant emissions, and is one of the most potential new energy power generation devices in the future. However, at low and medium temperature (below 800℃), the cathode impedance of SOFCs will increase sharply, resulting in adverse effects on cell performance. Finding cathode materials that can work at low and medium temperature is the key to realize large-scale commercial application of SOFCs. LSCF cathode material is one of the commonly used cathode materials for solid oxide fuel cells because of its excellent electronic and ionic conductivity. However, its cathode performance cannot meet the requirements of commercial applications. At high temperature, solid-state reactions are easy to occur between LSCF and commonly used electrolyte materials such as YSZ, SSZ and LSGM, resulting in the formation of an intermediate phase that is not conducive to Oxygen Reduction Reaction (ORR). In this paper, LSCF and Gd0.2Ce0.8O2 (GDC) were combined by ball milling to prepare composite cathode. XRD test found that the two powders mixed at high temperature did not produce new substances, with good chemical compatibility. The electrical conductivity test showed that the electrical conductivity of the composite LSCF decreased significantly from 227 Sꞏcm-2 at 650℃ to 115, 90 and 77 Sꞏcm-2 at 550℃, respectively. The composite cathode with a composite ratio of 6:4 has the lowest polarization impedance, only 0.10 Ωꞏcm2 at 800℃. The discharge test shows that the cathode with the mass ratio of 6:4 LSCF to GDC has the best performance, and the power density is 328 and 256 mW/cm2 at 800 and 750℃, respectively. The performance of the cathode has good stability after working for 50h.
Analysis on Dynamic Changes of Roliai Laterite Nickel Mine from 2013 to 2020
Authors: Zhang Xian , Chen Li , Li Wei , Li Yu , Chen Haomin
Published: July 2023

In order to accurately obtain the mining activities of Roliai laterite nickel mine, based on the remote sensing technology and object-oriented image analysis, methods of multi-scale segmentation based on scale optimization and optimal classification threshold selection were used to extract nine mining activity elements from WorldView II images of of 2013 and 2020 respectively. According to the extraction results, the dynamic changes of each element from 2013 to 2020 were analysed from the aspects of area and intensity. Our accuracy evaluation results showed that the overall accuracies of the two extraction results are higher than 90%, and the Kappa coefficients are higher than 0.81. From 2013 to 2020, the mining scale and mining intensity of Roliai laterite nickel mine showed a trend of rapid expansion on the whole, in which the mining area increased the most, reaching 1.02 km2, and the average annual change intensity was intense, and the corresponding dump area also increased by about 0.35 km2. In the past seven years, Roliai laterite nickel mine has developed from the stage of exploration and mining to forming a relatively complete industrial chain of mining, milling and metallurgyy, entering a development stage of rapid expansion.
Experimental Study on Stress Sensitivity Evaluation and Permeability Anisotropy of Shales in Songliao Basin
Authors: Ju Changhao , Yang Erlong
Published: July 2023

Shale oil and gas resources are abundant in Songliao Basin, and shale reservoirs tend to have certain permeability anisotropy with different pore or laminar structures in different directions, and there is no experimental analysis of shale anisotropy and reservoir sensitivity. To solve this problem, this paper tests the shale permeability by pulse decay method, obtains the variation curve of permeability and effective stress, and analyzes the experimental data. The experimental results of permeability show that the permeability of shale in Songliao basin is basically 10-4mD, and the permeability parallel and perpendicular to the laminae shows strong anisotropy, and the permeability perpendicular to the laminae is about 3%-14% The permeability of different rock samples decreases exponentially with the increase of effective stress. It provides basic data support to ensure the development of shale oil in Songliao Basin.
Study on Sealing Depth Optimization of Gas Drainage Borehole in Coal Seam
Authors: Chen Bin
Published: July 2023

To determine the reasonable sealing depth of the drainage borehole in the coal seam along lane W33011 of the Sihe coal mine and improve sealing quality based on the mine geological conditions, FLAC3D numerical simulation software was used to simulate the stress distribution and fracture development of coal body around the roadway after the roadway excavation. YFZ3 hole sealing quality detector was adopted to detect the hole sealing quality and leakage position. The reasonable drilling depth in the test area was determined to be 15m, effectively improving the gas drainage effect. This technology has important reference significance for improving the quality of hole sealing in other mines.
Research on Benefit Assessment of Multi-scenario Integrated Energy System
Authors: Liu Yujiao , Li Yan , Li Guoliang , Wang Ruiqi , Yang Le
Published: July 2023

With the rapid development of economy, China’s energy is in the stage of rapid transformation, and the market demand for comprehensive energy service in the whole society is increasing. Therefore, China needs to vigorously promote the construction of a comprehensive energy system energy supply mode with new energy as the main body, so as to realize the reasonable allocation of resources and the high proportion of clean energy consumption. To effectively evaluate the quality of the system operating benefits, this paper with a variety of typical comprehensive energy system as the background, through the establishment of comprehensive energy system scenario operating benefit evaluation index system, build index based on hierarchical analysis method weight model and entropy method of fuzzy comprehensive evaluation model, evaluate the benefits of various types of comprehensive energy system.
Study on Building Energy Saving Effect and Thermal Response of Roof Greening in Extremely Hot Weather
Authors: Qin Bingduo , Zou Weina , Jiang Nan , Lu Yi
Published: July 2023

As the main living space and carrier of the population, cities and buildings have become more seriously affected by changes in global environment in recent years. The deteriorating living environment has brought about the quality of survival of the population, the government’s administrative management, and the sustainable development of the environment. This article has found that green roofs on urban environmental management and building energy consumption have found that green roofs can have an important impact on urban environmental management. In extreme weather events, green roof has a maximum cooling effect of 26℃ in the daytime, and its warming effect at night has been suppressed to a certain extent; the heat preservation time of the green roof can be up to 17 hours after the superposition of precipitation weather incidents, and its heat preservation effect is positively related to the temperature in the daytime. The green roof can reduce the energy consumption of the building by 106W/ ㎡/d in the extreme weather incident, while its energy -saving effect is reduced to 45W/m2/d after superimposing the precipitation meteorological incident.
Analysis of Carbon Emission Factors in China and Japan Based on LMDI
Authors: Zhu Ziyao
Published: July 2023

From 2000 to 2015, China’s industry and economy developed rapidly, while at the same time, it became the world’s largest carbon emitter. China’s development trajectory in the 15 years since 2000 is similar to Japan’s in the 1960s and 1980s. This paper used the Logarithmic mean Divisa index (LMDI) method to estimate the impact factors of carbon emissions in China from 2000-2015 and in Japan from 1971-1986. The differences and commonalities of carbon emissions between the two countries in the two periods were discussed by comparing the driving factors of carbon emissions. On this basis, corresponding policies were provided in this paper.
A Comparison of Different Remediation Technologies of Contaminated Agricultural Soils
Authors: Liu Xinyue , Qi Weijun , Cui Shuang , Lv Lianghe , Jiang Jianyu , Jiang Jing , Zhu Ziyue
Published: July 2023

Soil contamination is a major threat to the sustainability of agricultural fields and the safety of food production. This paper presented the remediation techniques, including surface covering, encapsulation, thermal restoration, stabilization, solidification, phytoremediation, bioremediation, and combined remediation. Bioremediation, which uses microorganisms to break down contaminants, has gained popularity due to its low cost and minimal secondary pollution. In conclusion, remediation techniques for soil contamination in agricultural fields are essential for maintaining the environmental quality of agricultural products. By utilizing a combination of techniques, we can effectively remediate the soil and ensure the safety of food production.
Environmental Protection Tax Policy and Green Innovation of Heavy-Polluting Enterprises: Evidence from China
Authors: Hong Liming , Zhang Changhong , Xing Xiangjie , Shu Shulei
Published: July 2023

Since 2018, China has implemented the Environmental Protection Tax as a market-based envi-ronmental regulation tool to encourage enterprises, especially heavy-polluting ones, to reduce emissions and engage in green innovation. The effectiveness of this policy in promoting green innovation has become a focal point of attention for Chinese society, as it directly relates to the coordinated high-quality development of the economy and environmental protection, as well as the achievement of China’s “carbon peaking and carbon neutrality goals”. This study evaluates the green innovation effect of the Environmental Protection Tax policy on heavy-polluting enterprises in China using micro-data of listed enterprises from 2003 to 2019, based on the new market-oriented environmental regulation tool. We employ the propensity score matching and differ-ence-in-differences method (PSM-DID) to follow up on the green innovation effect of China’s Environmental Protection Tax policy and reveal its implementation effect. Empirical results indicate that, first, the Environ-mental Protection Tax policy contributes to heavy-polluting enterprises’ R&D innovation of green patents, and this conclusion holds through various robustness tests. Second, the policy’s impact on green innovation types of heavy-polluting enterprises exhibits heterogeneity, with a more significant positive effect on the utility model patent than on the invention patent. Third, the green innovation effect of the policy differs ac-cording to regional economic development and enterprise ownership attributes. Finally, financing constraints do not significantly affect the green innovation of heavy-polluting enterprises. These enterprises remain pro-active in green innovation, even under high financing constraints. To further promote green innovation of heavy-polluting enterprises and achieve China’s dual carbon goals, the government should continue to imple-ment and improve the Environmental Protection Tax policy, leveraging its positive effect on green innovation.