bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Analysis of Risk and Return of Manufacturing Companies: A Five-Year Study-(2019-2023)
Authors: - Bhoomika Chavan , - Namrata Burbure
Published: April 2024

The study employs both quantitative and qualitative research approaches to assess the historical performance of a selected group of Manufacturing companies in terms of risk-adjusted returns. In order to evaluate the risk and return profiles of Manufacturing companies, a number of financial measures are looked at, such as ROI, beta coefficients, and stock price volatility. To further assist investors, financial experts, and policymakers, the study also investigates the connection between economic and financial variables and stock returns. The research process includes gathering information from primary and secondary sources, choosing Manufacturing firms according to predetermined standards, and using statistical analysis tools like regression and correlation analysis. The results underscore the variation in the financial performance and risk profiles of Manufacturing firms, underscoring the significance of making well-informed investment decisions tactics and market forecasts in the ever-changing manufacturing industry. For investors looking to maximise their investment returns inside the Manufacturing Companies, the findings provide practical insights.
Empowering Rural Transformation: Assessing the Impact of MPLADS Funds Utilisation on SAGY Initiatives in Chandigarh's Sansad Adarsh Gram Yojana Village
Authors: - Vivek Sangwan , - Dr. B. Parkash
Published: April 2024

This study evaluates the impact of Member of Parliament Local Area Development Scheme (MPLADS) funds utilization on Sansad Adarsh Gram Yojana (SAGY) initiatives in Chandigarh's Sansad Adarsh Gram Yojana village. Utilising quantitative analysis, the research examines the distribution and allocation patterns of MPLADS funds across various project categories within the SAGY framework. Data obtained from the MPLADS office include project names, categories, expenditures, and work numbers for projects executed during Phase-I of SAGY. Findings reveal significant investment across sectors such as healthcare, sanitation, infrastructure, and livelihood enhancement. The study underscores the importance of continuous monitoring and evaluation to optimise resource allocation and enhance community development outcomes.
Fundamentals of Innovation and Venture Development in Entrepreneurship
Authors: - Palak Jain , - Prachi Daga , - Anurudh Singh , - Arnab J , - Rishita Kothari
Published: April 2024

The purpose of this study is to look into how the generational divide affects mental health in various age groups. Data was gathered from individuals of different generations through surveys and interviews using a mixed method approach. While qualitative findings offered complex perspectives on intergenerational dynamics and their psychological ramifications, quantitative analysis demonstrated an association between perceived generational disparities and mental health outcomes. Research indicates that closing the generational divide may lessen mental health issues, emphasizing the value of intergenerational dialogue and understanding in fostering general well-being.
THE EFFECT OF CAPITAL STRUCTURE AND PROFITABILITY TO FIRM VALUE
Authors: Nainggolan Kelian Stephen Karuyan , Hutabarat Francis
Published: April 2024

Abstract
The purpose of the research is to obtain empirical evidence about the impact of growth, capital structure and profitability to firm value. The sample in this research is Index BUMN20 company which listed in Indonesia Stock Exchange during the period of 2019 –2022. The source of the data of this research was conducted from annual report and sustainability report. This research is using quantitative approach with multiple linear regression analysis method. The result in this research is suggested to find the effect of capital structure and profitability on firm value.
Efficient Skin Lesion Detection using YOLOv9 Network
Authors: Faruq Aziz  , Saputri Daniati Uki Eka
Published: April 2024

Skin lesion detection plays a crucial role in dermatological diagnosis and treatment. In this study, we propose an efficient approach for skin lesion detection using the YOLOv9 network. Leveraging state-of-the-art deep learning techniques, our model demonstrates robust performance in accurately identifying various skin lesion types, including acne, atopic dermatitis, keratosis pilaris, leprosy, psoriasis, and wart. We conducted comprehensive experiments using a curated dataset comprising 2721 training images, 288 validation images, and 145 test images. The model was trained and evaluated based on standard metrics such as Precision, Recall, and mean Average Precision (mAP). Our results indicate promising detection accuracy, with an overall Precision of 60.5%, Recall of 86.0%, and an mAP of 81.4%. Class-wise analysis reveals varying levels of performance across different disease classes, highlighting the model's proficiency in detecting common dermatological conditions such as acne and wart lesions. Furthermore, we provide insights into potential challenges and limitations, including dataset size and class imbalance, and discuss avenues for future research to address these issues. Our study contributes to the advancement of AI-driven solutions for dermatological diagnosis and underscores the efficacy of the YOLOv9 network in skin lesion detection
Prevalence, Effects and Associated Risk Factors of Burnout among Medical Students in Guyana
Authors:   Jamain Hatton, Lequita Pryce, Charlan Abrams, Andrew Hutson, Ede Tyrell, Bibi Ally-Charles, Cecil Boston, Davon Van-Veen, Marcel Persaud, Nancy Sitchao, Latoya Harris and Jaleei Acindor
Published: April 2024

Objectives: To determine the rate of burnout among medical students of Guyana and to identify the causes and effects of burnout among those medical students affected. Design & Methods: This cross-sectional, quantitative study surveyed 238 medical students from all five medical schools in Guyana. The Burnout Inventory Student Survey (MBI-SS) score was used to determine the risk of burnout among the surveyed students. A piloted, online, de novo questionnaire was used to evaluate the variables recorded on the questionnaire including age, gender, year of study, employment status, causes, effects of burnout inter alia. All quantitative data were analyzed using SPSS v. 26.0 with the chi square and independent samples t-test being used to assess the association between variables. (p=0.05). Results: Data on 238 medical students were analysed (F=152, M=86), 51.3% of surveyed medical students showed signs of high burnout. (M=48.3%, F=61.8%, p<0.000, OR=3.4). While there was no significant difference between burnout rates of students in the 1st and 5th years (p=0.07), the 5th years were 3.7 times more at risk for burnout than their first years. Majority of the respondents attributed the cause of burnout to ‘poorly designed curriculum’ and ‘high tuition fees.’ Consequently, 36.1% of the respondents have ‘thoughts of suicide’, 25.4% engage in ‘safe/unsafe sexual gratifications’, and others use alcohol/ ‘hard’ drugs to cope with burnout. Conclusions: Medical students are at a high risk of burnout. Medical schools need to design programmes to address the mental health of its populace and reduce the prevalence and effects of burnout.
Stochastic dynamics mass spectrometric structural analysis of poly(methyl methacrylate)
Authors: Ivanova Bojidarka
Published: April 2024

Polymers such as poly(methyl methacrylate), comprising of all-carbon backbones are regarded as ubiquitous functional materials mainly due to their low cost, unique physical properties, and impressive robustness. The latter properties are results from relative chemical inertness of the polymer backbone carbon–carbon bonds. The highlighted stability crucially challenges not only innovations to plastic recycling polymer materials, but also developments of reliable analytical protocols for determining both quantitatively and structurally polymers. Despite, the fact that there are numerous applications of mass spectrometric methods to polymer science, the analysis involves chiefly annotation of monomers of polymers and additives, owing to the fact that the additives are low molecular weight analytes. The exact structural determining of end-chain groups, particularly highlighting chemically substituted end carbon–carbon bond represents significant challenge even utilizing the superior features of the analytical mass spectrometric instrumentation. This study, in the latter context, illustrates innovative stochastic dynamics approach and model equations capable of not only determining unambiguously substituted carbon–carbon end chain of the entitled polymer but also to predict mass spectra of its derivatives: thus, extending crucially the applicability of the method to many fields of the fundamental scientific and industrial research. The latter claim is argued still at the beginning of the study with the achieved method performances showing |r|=0.99998. The study utilizes experimental and theoretical mass spectrometric data on high resolution electrospray ionization mass spectrometry; high accuracy quantum chemical static methods, molecular dynamics; and chemometrics.
Ubiquitin-Conjugating Enzyme E2C Activates Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway to Promote Growth and Migration of Cutaneous Squamous Cell Carcinoma Cells
Authors: Jiang Yannan , Liu Runqiu , Li Xinghui , Wang Yunjiang
Published: April 2024

Cutaneous squamous cell carcinoma is prone to metastasis at its advanced stage. Previous studies reported that the ubiquitin-conjugating enzyme E2C is a proto-oncogene that causes cancer in various tumors. This study aimed to investigate the role of the ubiquitin-conjugating enzyme E2C in cutaneous squamous cell carcinoma. We initially analyzed the expression profile in the gene expression omnibus database. We obtained the intersection genes, established a protein-protein interaction network, and identified ubiquitin-conjugating enzyme E2C as the key gene. Furthermore, microarray data revealed that the ubiquitin-conjugating enzyme E2C expression is elevated in cutaneous squamous cell carcinoma. Ubiquitin-conjugating enzyme E2C overexpression plasmids and siRNA of ubiquitin-conjugating enzyme E2C were transfected into cutaneous squamous cell carcinoma cells to analyze the effects of ubiquitin-conjugating enzyme E2C on cutaneous squamous cell carcinoma cell proliferation, migration, and invasion. The expression of associated proteins was detected using Western blot assay to confirm the impact of the ubiquitin-conjugating enzyme E2C on the phosphatidylinositol-3-kinase/threonine kinase signaling pathway. Ubiquitin-conjugating enzyme E2C knockdown inhibited cutaneous squamous cell carcinoma cell viability, migration, and invasion, and the phosphatidylinositol-3-kinase/threonine kinase signaling pathway, while ubiquitin-conjugating enzyme E2C overexpression had opposite results. In summary, Ubiquitin-conjugating enzyme E2C is a potential therapeutic target for cutaneous squamous cell carcinoma since it encourages the proliferation and migration of cutaneous squamous cell carcinoma cells.
PANDANGAN HUKUM PIDANA TERHADAP KASUS POLITIK UANG DALAM PEMILU TAHUN 2024
Authors: Pratama Adrian , Arif Fadhlurrahman  , Angga Arniya Putra  , Tegar Gala Samudra  , Willy Syain Islami  , Yon Efri
Published: April 2024

Political corruption is a prominent phenomenon in modern politics, influencing political processes in various countries, including Indonesia. This article delves into the evolution of politics in Indonesia post-reform, with a focus on the role of political parties and the practice of money politics in elections. The main discussion explores the phenomenon of money politics, highlighting its correlation with political corruption and the role of political parties in society. Additionally, the article examines factors influencing the practice of money politics, such as the lack of closeness between political parties and the public, individual education levels, and low welfare standards. This analysis provides deep insights into the dynamics of money politics.By summarizing findings and implications from the analysis, this article suggests that money politics poses a serious challenge to the integrity of democracy and political justice. Therefore, efforts to prevent money politics should be a priority in strengthening a cleaner, fairer, and more transparent political system. Thus, this article makes a significant contribution to understanding money politics and efforts to address it for the sake of a healthy and sustainable democracy.
Meningkatkan Pemahaman di Kalangan Masyarakat Tentang Bahaya Politik Uang Dalam Pemilu 2024
Authors: Sonia Citra , Juniaro Abil , Hazmi Raju Moh , Ilhamsyah Ridhwan
Published: April 2024

The practice of money politics by some parties has been considered normal in elections in Indonesia. The discussion of money politics has been widely discussed in the literature on voter behavior in Indonesia, both from a political, sociological, psychological, and rationale choice (political economy) perspective. There are also studies that pay attention to the influence of money politics in elections. Academic explanations of the electoral impact of money politics are also discussed in several international studies. The problem is how the solution in preventing the occurrence of money politics transactions in the election, the alternative analysis process is to use normative juridical methods with historical empirical data, through socialization, and face-to-face, participant observation and the amount of participation from the context of money politics, the role of institutions in the process of educating mass awareness through party doors and community leaders is an alternative solution to close the path of violation of election law, on the other hand public awareness and political parties and candidates are the ones who really play a role in breaking the chain of the spread of money politics transactions.
Prediction of Optimal Parameter Settings and Significant Parameter for Reduced Geometric Deviations Through Multi Criteria Decision Making and Machine Learning Algorithms
Authors: Selvaraj Subhash , P.k. Rajesh
Published: April 2024

Part dimensional inaccuracies serve as a barrier from adopting Additive Manufacturing (AM) processes in mass production. Fused Deposition Modeling (FDM) is a thermoplastic based low cost AM process which can create conceptual models, prototypes and end user industrial parts. The current study involves predicting the optimal parameter settings and significant parameter for reduced geometric deviations in printed part using Nylon filament reinforced with 20% carbon fiber. Five input factors such as build orientation, layer thickness, infill density, raster angle and infill pattern have been considered for preparing the experimental layout through taguchi�s mixed fractional factorial design. The changes in length, width and thickness of the printed part from CAD value have been evaluated individually through ANOVA and Signal to Noise Ratio method (Smaller the better). Layer thickness is significant only for variations in length, but build orientation affects both width and thickness dimensions. The geometric deviations are further analyzed using combined multi criteria decision making (MCDM) approaches such as Entropy-CoCoSo and PCA-TOPSIS. The optimal parameter settings obtained for reduced geometric deviations is found to be Flat orientation, 0.1mm layer thickness, 50% infill density, 0� raster angle and cubic infill pattern. Layer thickness is found to be highly significant parameter influencing the geometric deviations subsequently followed by build orientation from both the MCDM methods. The multi response performance index values obtained from Entropy-CoCoSo has been trained using classification algorithms such as decision tree, random forest and Naive Bayes. Naive Bayes algorithm outperformed other methods with highest classification accuracy of 99.4% in a training-testing split ratio of 75:25.
Enhanced Electric Photoconductivity of Modified Epoxy Resin
Authors: Saracu Gabriel , Sarateanu Sorin , Bria Vasile , Buciumeanu Mihaela , Circiumaru Adrian
Published: April 2024

The basic idea of this study is based on the hypothesis that it is possible to obtain nanostructures by stimulating local chemical reactions. Starting with this hypothesis we assumed that it is possible to disperse some inorganic agent into the epoxy resin and stimulating the mixtures we could get some nano-structures what are changing the basic electric behaviour of the polymer matrix. We dissolved some metallic chlorides in DMF (dimethylformamide) and we mixed together the solution with the epoxy resin (the main component). Applying various external stimuli we get materials showing various properties, different from the epoxy resin properties. The electric photoconductivity is increased (in some cases) but the mechanical properties are damaged due the solvent presence into the polymer matrix.
The reality of administrative and technical empowerment of the coaching staff in basketball sports clubs
Authors: Hussein Ali
Published: April 2024

The importance of research lies in the results of this research and its importance in developing the performance of coaches if committed, which in turn will lead to higher overall performance in the Iraqi Basketball League the research aims to identify the reality of empowerment among the coaches of the Iraqi Basketball Federation and employees of the Iraqi clubs, The research sample consisted of Iraqi Basketball Federation coaches and staff at Baghdad Clubs who were commissioned in the years (2018, 2019, 2020, 2021) Training basketball teams in Iraq clubs, and their number was (110). The research tool for gathering information was a questionnaire that the researcher built, subjected to scientific requirements, and presented to the experts until it became final. The researcher reached several conclusions, the most important of which is that the management used by the clubs is bureaucratic management that believes in confining authority to senior management and that all areas of empowerment (Information, power participation, development, and training) need to be strengthened, and one of the most important recommendations recommended by the researcher is to establish clear criteria and information for everyone on everything about choosing (assistants, players, camps, training halls, fixtures, tournaments, friendly matches) and other logistics.
Aerodynamics Analysis Comparison between NACA 4412 and NREL S823 Airfoils
Authors: Fayyad Sayel M. , Al Alawin Aiman , Abu-Ein Suleiman , Abulghanam Zaid , Alsabag Abdel Salam , Rawashdeh Mohannad O. , Momani Muntaser , Momani Waleed
Published: April 2024

This paper presents a study of the aerodynamics of a wing or bluff bodies and compares different wing types' behavior against aerodynamic forces. NACA 4412 and NERL S823 airfoils will be analyzed numerically using the ANSYS simulation. The methodology used in this paper depends on collecting data from the last studies, studying the analyzed airfoil models, and constructing an analytical model to show the aerodynamic effects on NACA 4412 and NERL S823 airfoils, and find the total solution. A comparison between NACA 4412 airfoil and NREL'S S823 is presented. It was found that the lift coefficient for NACA 4412 values is higher than that of NREL S823 airfoil but for NACA 4412 such values are decreasing as the angle of attack (AoA) is increasing till 8ᵒ of AoA after that Cl values are increasing slightly. In contrast, for NREL S823 airfoil the values of lift coefficient (Cl) are increasing with AoA till 8ᵒ after that they become constant or slightly decreasing, while for drag coefficient, it can be noticed that values of drag coefficient (Cd) for NACA 4412 are lower than that of NREL S823 airfoils and for all values of angle of attack, also values for both airfoils are decreasing with AoA till 8° and then slightly increased.
Influence of Chemical and Radiation on an Unsteady MHD Oscillatory Flow using Artificial Neural Network (ANN)
Authors: Kavitha R. , Mahendran M.
Published: April 2024

This paper delves into the intricate interplay between chemical and thermal radiation in the context of an unstable magnetohydrodynamic(MHD) oscillatory flow through a porous medium. The fluid under investigation is presumed to be incompressible, electrically conductive, and radiating with the additional influence of a homogeneous magnetic field applied perpendicular to the channel’s plane. Analytical closedform solutions are derived for the momentum, energy, and concentration equations providing a comprehensive understanding of the system’s behavior. The investigation systematically explores the impact of various flow factors, presenting their effects through graphical representations. The governing partial differential equations (PDE) of the boundary layer are transformed into a set of coupled nonlinear ordinary differential equations (ODE) using a closed-form method. Subsequently, an artificial neural network (ANN) is applied to these ODEs, and the obtained results are validated against numerical simulations. The temperature profiles exhibit oscillatory behavior with changes in the radiation parameter (N), revealing insights into the system’s dynamic response. Furthermore, the paper uncovers that higher heat sources lead to increased temperature profiles. Additionally, concentration profiles demonstrate a decrease with escalating chemical reaction parameters, with a reversal observed as the Schmidt number (Sc) increases. This study highlights the efficacy of an ANN model in providing highly efficient estimates for heat transfer rates from an engineering standpoint. This innovative approach leverages the power of artificial intelligence to enhance our understanding of complex fluid magnetohydrodynamics and porous media flows.
Suspended Mooring Line Static Analysis using Internal XFlow Capabilities
Authors: Gil Miguel , Torres Alexia , Fuertes Juan Pablo , Armañanzas Javier , Leon Javier
Published: April 2024

In the present study, different configurations of a mooring line under a static case are analyzed using the CFD software SIMULIA XFLOW 2022X. Native XFlow geometries employed in the simulation of small springs are used to perform simulations of mooring systems, along with 6 DOF joints, and performing discretization depending on the necessities. Fairlead tensions are compared to experimental data of cables employed in the mooring of DeepCWind semisubmersible platform at 1/40 scale, and to computational model using OPASS. Additionally, the location of different points of the suspended chain in the resting catenary shape is compared to the Quasi-Static model.
Monialaisen yhteistyön kehittyminen työkyvyn tukemisessa
Authors: Henriksson Mikko , Unkila Kirsi , Hirvonen Maria , Nevala Nina
Published: April 2024

Työkyvyn ja työllistymisen tuen ammattilaisten tulee ylittää hallinnonrajoja vastatakseen asiakkaidensa vaihteleviin tarpeisiin. Työkykyohjelmassa kehitetyllä Työkyvyn tuki -koulutuksella pyrittiin kehittämään ammattilaisten monialaisen yhteistyön osaamista. Koulutus arvioitiin kyselyillä ennen koulutusta ja koulutuksen päättyessä sekä puoli vuotta koulutuksen jälkeen. Arviointitulosten mukaan koulutukseen osallistuneiden ammattilaisten ymmärrys ja osaaminen palvelujärjestelmästä, eri toimijoista ja työkyvyn tuen keinoista lisääntyivät koulutuksen aikana. Koulutuksen käyneiden ammattilaisten mukaan monialaista yhteistyötä vaikeuttaa etenkin resurssien puute ja kiire mutta myös epätietoisuus monialaisen työskentelyn hyödyistä. Ammatillista kontekstia laajemmin on kehitettävä monialaisen yhteistyön johtamista ja yhteistyötä eri hallinnonalojen välillä.
Cellular strategies to induce immune tolerance after liver transplantation: Clinical perspectives
Authors: Zhou Ai-Wei , Jin Jing , Liu Yuan
Published: April 2024

Liver transplantation (LT) has become the most efficient treatment for pediatric and adult end-stage liver disease and the survival time after transplantation is becoming longer due to the development of surgical techniques and perioperative management. However, long-term side-effects of immunosuppressants, like infection, metabolic disorders and malignant tumor are gaining more attention. Immune tolerance is the status in which LT recipients no longer need to take any immunosuppressants, but the liver function and intrahepatic histology maintain normal. The approaches to achieve immune tolerance after transplantation include spontaneous, operational and induced tolerance. The first two means require no specific intervention but withdrawing immunosuppressant gradually during follow-up. No clinical factors or biomarkers so far could accurately predict who are suitable for immunosuppressant withdraw after transplantation. With the understanding to the underlying mechanisms of immune tolerance, many strategies have been developed to induce tolerance in LT recipients. Cellular strategy is one of the most promising methods for immune tolerance induction, including chimerism induced by hematopoietic stem cells and adoptive transfer of regulatory immune cells. The safety and efficacy of various cell products have been evaluated by prospective preclinical and clinical trials, while obstacles still exist before translating into clinical practice. Here, we will summarize the latest perspectives and concerns on the clinical application of cellular strategies in LT recipients.
Hepatolithiasis: Epidemiology, presentation, classification and management of a complex disease
Authors: Motta Rodrigo V. , Saffioti Francesca , Mavroeidis Vasileios K
Published: April 2024

The term hepatolithiasis describes the presence of biliary stones within the intrahepatic bile ducts, above the hilar confluence of the hepatic ducts. The disease is more prevalent in Asia, mainly owing to socioeconomic and dietary factors, as well as the prevalence of biliary parasites. In the last century, owing to migration, its global incidence has increased. The main pathophysiological mechanisms involve cholangitis, bile infection and biliary strictures, creating a self-sustaining cycle that perpetuates the disease, frequently characterised by recurrent episodes of bacterial infection referred to as syndrome of “recurrent pyogenic cholangitis”. Furthermore, long-standing hepatolithiasis is a known risk factor for development of intrahepatic cholangiocarcinoma. Various classifications have aimed at providing useful insight of clinically relevant aspects and guidance for treatment. The management of symptomatic patients and those with complications can be complex, and relies upon a multidisciplinary team of hepatologists, endoscopists, interventional radiologists and hepatobiliary surgeons, with the main goal being to offer relief from the clinical presentations and prevent the development of more serious complications. This comprehensive review provides insight on various aspects of hepatolithiasis, with a focus on epidemiology, new evidence on pathophysiology, most important clinical aspects, different classification systems and contemporary management.
Growth differentiation factor-15 serum concentrations reflect disease severity and anemia in patients with inflammatory bowel disease
Authors: Tonkic Ante , Kumric Marko , Akrapovic Olic Ivna , Rusic Doris , Zivkovic Piero Marin , Supe Domic Daniela , Sundov Zeljko , Males Ivan , Bozic Josko
Published: April 2024

BACKGROUND

Population of patients with inflammatory bowel disease (IBD) is burdened by various extraintestinal manifestations which substantially contribute to greater morbidity and mortality. Growth-differentiation factor-15 (GDF-15) is often over-expressed under stress conditions, such as inflammation, malignancies, heart failure, myocardial ischemia, and many others.

AIM

To explore the association between GDF-15 and IBD as serum concentrations of GDF-15 were shown to be an independent predictor of poor outcomes in multiple diseases. An additional aim was to determine possible associations between GDF-15 and multiple clinical, anthropometric and laboratory parameters in patients with IBD.

METHODS

This cross-sectional study included 90 adult patients diagnosed with IBD, encompassing both Crohn’s disease (CD) and ulcerative colitis (UC), and 67 healthy age- and sex-matched controls. All patients underwent an extensive workup, including colonoscopy with subsequent histopathological analysis. Disease activity was assessed by two independent gastroenterology consultants specialized in IBD, employing well-established clinical and endoscopic scoring systems. GDF-15 serum concentrations were determined following an overnight fasting, using electrochemiluminescence immunoassay.

RESULTS

In patients with IBD, serum GDF-15 concentrations were significantly higher in comparison to the healthy controls [800 (512-1154) pg/mL vs 412 (407-424) pg/mL, P < 0.001], whereas no difference in GDF-15 was found between patients with CD and UC [807 (554-1451) pg/mL vs 790 (509-956) pg/mL, P = 0.324]. Moreover, multiple linear regression analysis showed that GDF-15 levels predict CD and UC severity independent of age, sex, and C-reactive protein levels (P = 0.016 and P = 0.049, respectively). Finally, an association between GDF-15 and indices of anemia was established. Specifically, negative correlations were found between GDF-15 and serum iron levels (r = -0.248, P = 0.021), as well as GDF-15 and hemoglobin (r = -0.351, P = 0.021). Accordingly, in comparison to IBD patients with normal hemoglobin levels, GDF-15 serum levels were higher in patients with anemia (1256 (502-2100) pg/mL vs 444 (412-795) pg/mL, P < 0.001).

CONCLUSION

For the first time, we demonstrated that serum concentrations of GDF-15 are elevated in patients with IBD in comparison to healthy controls, and the results imply that GDF-15 might be involved in IBD pathophysiology. Yet, it remains elusive whether GDF-15 could serve as a prognostic indicator in these patients.
PERLINDUNGAN HUKUM TENAGA KESEHATAN (PENATA ANESTESI) SETELAH TERBITNYA UNDANG-UNDANG KESEHATAN NOMOR 17 TAHUN 2023
Authors: Wahyudiono Gunawan , Ismono Joko , Daim Nuryanto A.
Published: April 2024

Pelayanan anestesiologi dan terapi intensif di rumah sakit merupakan salah satu bagian dari pelayanan kesehatan yang berkembang cepat seiring dengan peningkatan ilmu pengetahuan dan teknologi di bidang anestesi. Undang-undang No. 17 Tahun 2023 tentang Kesehatan ini memberikan secercah harapan agar ada solusi untuk pemenuhan kebutuhan dokter spesialis/subspesialis di berbagai daerah. Pembentukan Undang-undang Nomor 17 Tahun 2023 tentang Kesehatan ini terbukti menimbulkan adanya penghambatan / penghalangan. Regulasi sudah memberitahu bagaimana Rumah sakit sebagai perpanjangan tangan dari menteri, pemerintah daerah provinsi maupun pemerintah daerah kabupaten/kota seharusnya bertindak, bagaimana responnya dan sanksi-sanksinya. Namun adanya penata anestesi yang berpraktik tanpa STRPA dan SIPPA merupakan indikasi bahwa hukum tidak bekerja dalam masyarakat secara maksimal.
Alt Beden Elektromyostimülasyon Antrenmanı Ve Detraining’in Performansa Etkileri
Authors: Kaçoğlu Celil
Published: April 2024

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Penolakan Radikalisme Agama melalui Idiom Palembang
Authors: Zuhdiyah Zuhdiyah , Hamzah Amir
Published: April 2024

This research aims to describe the forms of Palembang language idioms that are still used by the community and map the forms of community resistance to religious radicalism. This type of research is descriptive qualitative. The informants in this research were Palembang speakers in the Seberang Ulu and Seberang Ilir areas who were selected based on predetermined criteria. The research process started from desk-review, field observation, documentation, in-depth interviews and FGD. Data analysis in this research uses data reduction, presentation and drawing conclusions. The results obtained from the research are that there are 158 Palembang idioms that are still used by the public, and there are 10 idioms that are appropriate for resisting radicalization, namely: (1) Ado gawe, (2) Balak duobelas, (3) Besak kelakar, (4) Katek aguk, (5) Katek antanan, (6) Makan olo'an, (7) Ngeci'ke bala', (8) Pakem tuo, (9) Tempuan tahlil, (10) Wong kito galo. Rejection of destructive-anarchist actions both towards adherents of other religions and those of their own religion. This study illustrates the need for these idioms to be disseminated to the public and taught in schools. Further research needs to be carried out to fully understand how idioms can influence children's thoughts and behavior through experimental studies. Discussion and other limitations will be explained in this paper.
Collaborative Strategy in Improving the Quality of Extracurricular Services in Elementary Schools
Authors: Rifa'i Moh , Mubarok Naufal
Published: April 2024

The aim of this research is to find out the cooperation strategy for improving the quality of extracurricular services at MI Mambaul Ulum Bondowoso. This research uses a qualitative-descriptive approach. School leaders, teachers, and parents are informants who participated in this study. Data collection methods involve in-depth interviews, observations of educational activities, and document analysis. Source triangulation and data triangulation techniques are used to ensure the validity of the data. Research findings reveal some findings. First, extracurriculars can support each other and create holistic education. Second, integrated extracurricular service quality implementation also involves coordinated teacher resources, being a benchmark in reaching students with diverse motivations, and contributing to future development policy formulation.
Lighting in the Performance "Kapai-Kapai" by Arifin C Noer
Authors: Koswara Puji
Published: April 2024

This article focuses on lighting using GrandMA2 equipment, the work steps of a lighting designer, and the simulation of lighting arrangement work in the performance "Kapai-Kapai" by Arifin C Noer. This study aims to make lighting designs in theater performances with the script "Kapai-Kapai" by Arifin C Noer. This research is a type of action research that uses a qualitative approach, with library research methods to collect information, theories, and concepts related to lighting in the performing arts, especially theater. Research data sources include books related to performing arts, journal articles, and documents related to the performance "Kapai-Kapai." Meanwhile, data collection was obtained from observation and interviews. Data analysis is carried out qualitatively. Observational and interview data were analyzed to identify patterns, trends, and findings related to the application of lighting in the performance of "Kapai-Kapai." Modern equipment such as color-adjustable LED lights, special effects with projection, and automatic control allow performances to become even more dynamic and creative. Some lighting designers use computer simulations to plan light effects before the show begins. This allows them to test various scenarios and ensure that the lighting matches the artistic vision.
Development of Canva-Based Interactive Teaching Materials to Enhance Students' Critical Thinking Skills in Fiqh Learning at Islamic High School
Authors: Pulungan Ellly Damayanti , Ananda Rusydi , Rifa'i Muhammad , Mousthofa Ebaa
Published: April 2024

This project aims to promote critical thinking abilities among eleventh-grade students in the Social Sciences curriculum at MAN 1 Medan during Fiqh (Islamic Jurisprudence) studying, leveraging interactive teaching materials based on Canva that have been designed. This research uses Research and Development (R&D). The 4-D research design, which consists of four stages—define, design, develop, and disseminate—is used in this study's instructional material development. Thirty-three eleventh-grade Social Sciences students make up the research subjects. The interactive teaching materials based on Canva are highly valid based on the research and development findings. This is supported by the material validation score of 3.07, the subject matter expert assessment score of 3.23, and the language expert validation score of 3.30. The overall recapitulation score of 3.2 further confirms this conclusion. This suggests that the interactive educational resources created by Canva meet appropriate standards and can be utilized by educators and learners alike.
The New Protectionism: Risk Aversion and Access to Indigenous Heritage Records
Authors: Thieberger Nick , Aird Michael , Bracknell Clint , Gibson Jason , Harris Amanda , Langton Marcia , Sculthorpe Gaye , Simpson Jane
Published: April 2024

This article discusses the problems encountered in accessing archival Indigenous language records, both by Indigenous people looking for information on their own languages and by non-Indigenous researchers supporting language work. It is motivated by Indigenous people not being able to access materials in archives, libraries, and museums that they need for heritage reasons, for personal reasons, or for revitalisation of language or cultural performance. For some of the authors, the experience of using Nyingarn, which aims to make manuscript language material available for re-use today, has been dispiriting, with what we term the ‘new protectionism’ preventing use of these materials.
THE PROCEDURE FOR THE USE OF UNMANNED AERIAL VEHICLES TO CONDUCT RECONNAISSANCE ON THE GROUND IN WARTIME CONDITIONS
Authors: Boliubash O. , Ponomarov A. , Shulezhko V. , Shulezhko A.
Published: April 2024

The article reveals the peculiarities of using unmanned aerial vehicles for reconnaissance in the field in wartime.

The article reveals the essence and content of the use of unmanned aerial vehicles for reconnaissance, as well as the conditions and features of their effective use.

Study of the possibilities of using unmanned to conduct reconnaissance on the ground in wartime conditions has shown that this technology has great potential to improve operational intelligence and ensuring the safety of military personnel. The advantages of using unmanned aerial vehicles for reconnaissance are obvious. They can quickly and efficiently penetrate enemy territory, collect information territory, collect information and transmit it in real time. This makes it possible to Reduce the risk to the lives of servicemen, as they do not need to go to the front line the front line to conduct reconnaissance. In addition, unmanned aerial vehicles can operate in hazardous environments, such as radioactive contamination or chemicals where humans cannot enter. The use of unmanned aerial vehicles also ensures greater accuracy and objectivity in collecting information. They are equipped with various types of sensors, such as high-resolution cameras, thermal cameras, radars, etc., which provide detailed information about the territory, enemy positions and movements. This significantly improves the quality of intelligence and allows for more informed decisions on further actions.

In summary, research has shown that the use of unmanned aerial vehicles for reconnaissance in wartime has significant potential. They can collect information quickly, efficiently and safely, improving operational intelligence and ensuring the safety of soldiers. However, further research and development of new technologies is needed to improve the functionality and safety of unmanned aerial vehicles in warfare.
ANALYSIS OF THE CHARACTERISTICS AND CAPABILITIES OF MODERN VIBRATION AND STRAIN GAUGES OF MODERN MEASURING EQUIPMENT
Authors: Huzii Ye. , Arkushenko P. , Andrushko М. , Sadaiev A.
Published: April 2024

The article analyses the characteristics and capabilities of modern vibration and strain gauges, as well as the existing requirements for vibration measurement devices for wheeled armoured vehicles. The main physical parameters for assessing the strength and vibration characteristics of wheeled armoured vehicles to be measured are determined. Modern accelerometers for measuring vibration have better universal characteristics compared to other types of sensors, as well as a wide frequency and dynamic linearity range. The use of piezoelectric, strain gauge, magnetic induction and laser measuring equipment will allow to obtain physical values of vibration parameters and the stress-strain state of wheeled armoured vehicles and, using data acquisition systems and software, to analyse deviations of limit values in the design and components of the vehicle.

Improvement of the methodological apparatus for experimental studies of strength and vibration characteristics during testing of wheeled armoured vehicles will improve the quality and simplify the measurement process, which in turn will significantly reduce the time for testing prototypes and ensure timely delivery of weapons and military equipment (components) to the Armed Forces of Ukraine. The use of modern vibration and strain gauges to assess the strength and vibration characteristics of structures and their components will simplify and automate the measurement process, minimising possible errors during testing of armoured vehicles. The results of the work can be used for a rational and justified selection of vibration and strain gauges for testing wheeled armoured vehicles.
RESULTS OF THE EXPERIMENT USING NAVIGATIONAL ANTENNAS WITH CONTROLLED RECEPTION PATTERN ANTENNA FOR UAVS IN AREAS OF ACTIVE SUPPRESSION BY ELECTRONIC WARFARE MEANS
Authors: Los A. , Zhyrna O.
Published: April 2024

The article describes the trends in development, tactics, composition, and construction of Russia's electronic warfare means, as well as the primary objectives of interference. It describes methods effectively employed on the battlefield to reduce the impact of enemy EW assets on the navigation data quality of UAVs (Unmanned Aerial Vehicles). The general concept of using CRPA (Controlled Reception Pattern Antenna) for military users' navigation is outlined.

Experiments were conducted to assess the influence of EW means on one of the most popular CRPAs with four antenna elements in real conditions of active combat. Flights were carried out simultaneously by two UAVs, the first equipped with CRPA and the second integrated with a standard GNSS receiver. The flights were conducted under identical conditions, simultaneously conducting reconnaissance of the same targets. Data on the average height loss of navigation signal reception for UAVs were obtained.

According to the experiment results, the integration of CRPA with four antenna elements can be effective for strike UAVs with weapon release systems that require precise positioning for target engagement, provided that the flight altitude of such UAVs does not exceed 150-250 meters in areas with minimal enemy EW interference. Otherwise, it is recommended to use CRPA with 8 or more elements or explore other promising technologies.

Recommendations for integrating the aforementioned antennas are developed, and the accompanying issues associated with their application are discussed. The article also outlines options for expanding CRPA integration capabilities and ways to upgrade their software and hardware components.
THEORETICAL APPROACHES TO THE SELECTION OF DETECTION METHODS OF EXPLOSIVE DEVICES IN ENVIRONMENTS THAT CONCEAL THEM, ADVANTAGES AND DISADVANTAGES
Authors: Krivtsun V. , Lyashenko V.
Published: April 2024

The results of the analysis of trends in the development of armed struggle indicate the ever-increasing role of the use of mine weapons. At the same time, there is a significant imbalance between the development of mine weapons and detection means, which in turn causes a number of problematic issues in demining. It is noted that due to the aggression of the russian federation, Ukraine has become the most mined country in the world. In addition to the problem of demining the contaminated territory with explosive objects, the issue of reconnaissance of the area for mines and making passages in enemy minefields has become acute.

The paper analyzes the demining process, identifies the factors that influence it, and presents the main demasking factors of explosive objects, as well as the performance of terrain demining tasks. Taking into account these features, theoretical approaches to the detection and identification of explosive objects based on various physical principles are considered. An analysis of the use of the main methods of detection and identification of explosive objects is carried out, their advantages and disadvantages are determined.

Based on the analysis of theoretical approaches, a generalized characterization of the main methods of detecting explosive objects is given. It is noted that, taking into account the experience of performing demining tasks in the war of the russian federation against Ukraine, the main methods of searching for explosive objects are contact, mechanized, induction, optical, thermal and in some cases biophysical. Today, the use of advanced explosive detection methods is limited by the need to solve technical problems to reduce the number of false signals. The paper notes that in order to increase the efficiency of the process of detecting explosive objects and ensure proper safety, it is advisable to combine detection methods, as well as combine them with remotely controlled (robotic) means, as well as UAVs.
TEMPERATURE ERROR OF THE MEANS OF MEASURING THE GEOMETRIC CHARACTERISTICS OF BORES OF FIREARMS: MATHEMATICAL MODEL AND QUANTITATIVE EVALUATION
Authors: Kriukov O. , Mihura O.
Published: April 2024

The work is devoted to the construction of mathematical models and quantitative assessment of the components of the temperature error of a laser triangulation sensor for measuring the geometric characteristics of bores of firearms.

The existence of problematic issues in the field of evaluating the metrological characteristics of laser triangulation means for technical diagnostics of firearms barrel channels is highlighted. An analysis of publications

on the evaluation of the error of a laser triangulation sensor caused by the influence of ambient temperature is carried out, and known approaches to their mathematical modeling are considered. The need to develop mathematical models of the components of the temperature error of a laser triangulation sensor and to quantify this error is substantiated.

The parameters of the optical scheme of the laser triangulation sensor, whose deviation from their nominal (calculated) values will affect the conversion function, are determined. It is shown that the presence of a temperature error during the processing of measurement information will be perceived as an apparent change in the measured value with a constant input signal.

On the basis of algebraic transformations of expressions reflecting the relationship between the output value of a laser triangulation sensor and deviations of the optical circuit parameters from their nominal values, mathematical models of the temperature error components are obtained and presented in the form of error component limits at the input of the measuring instrument. The expressions for determining the confidence limits of the total temperature error, taking into account the correlation between its components, are substantiated.

A quantitative assessment of the temperature error for the characteristic combinations of weapon parameters (for four ranges of barrel calibers) in the range of ambient temperature variations inherent in the region where measurements are made is carried out. The results of the quantitative evaluation are presented in the form of graphs of the dependence of the limits of relative and absolute temperature errors on temperature and on the increase in the bore radius in the measurement range. The data obtained were analyzed, the peculiarities of the dependencies were determined, and conclusions were drawn about the compliance of the temperature error characteristics of the measuring instrument with the requirements for its accuracy.