bluuebunny/crossref_metadata_2025 huggingface dataset:
Breast Implant Illness Syndrome(BII): análise estatística envolvendo 167 mulheres
Authors: Pinto Maria Eduarda Guelfi , Guimarães Bruna Marcella Silva , Laurindo Lucas Fornari , Teixeira Daniel De Bortoli
Published: February 2023

A síndrome Breast Implant Illness (BII), popularmente conhecida como a doença do silicone, constitui de uma série de sintomas físicos e psicológicos incapacitantes e angustiantes. Dessa forma, o objetivo do presente artigo é verificar se a mulheres com a prótese apresentaram algum sintoma característicos da síndrome BII, se possuíam histórico familiar com algum sintoma característico da BII antes da colocação da prótese e, investigar a existência de associação entre faixa etária, técnica de cirurgia utilizada na colocação da prótese e volume dela, com variáveis sociodemográficas e se as pacientes foram informadas que poderiam desenvolver BII. Trata-se de um estudo primário transversal, qualitativo e descritivo com uma amostra de 167 mulheres. O resultado foi que houve significância estatística entre técnica utilizada (p= 0,024) com a variável motivo da cirurgia, entre o volume da prótese (p=0,024) e outra significância estatística foi encontrada na pergunta se foi informada que poderia desenvolver a BII (p=0,008) com a variável faixa etária. Para concluir o estudo mostrou que nas mulheres analisadas que apresentaram sintomas característicos da BII, foi observado que no histórico familiar possuía algum sintoma característico da BII, quanto ao volume da prótese notou-se que as mulheres com maiores volumes realizaram a cirurgia por questões estéticas, a técnica cirúrgica subglandular foi a mais utilizada em mulheres cujo motivo da realização era doença. A faixa etária que mais realizou cirurgia foram as adultas e as adolescentes foram o grupo etário mais informado sobre a possibilidade de desenvolvimento de BII do que as adultas.
Riscos à saúde das práticas médicas de antienvelhecimento: uma análise literária
Authors: Bugatti Victória , Paiva Aline Cardoso de , Amâncio Natália de Fátima Gonçalves
Published: February 2023

O fenômeno do envelhecimento populacional é crescente, na sociedade contemporânea, e apesar do aumento alarmante no número de idosos no mundo, muitos indivíduos pretender avançar os anos sem, necessariamente, envelhecer, isto é, contemplam o prolongamento da vida, no entanto, não almejam passar pelos processos deletérios do envelhecimento. Nesse sentido, a medicina, juntamente com outras áreas da saúde e da tecnologia, busca desenvolver métodos e práticas interventivas voltadas ao rejuvenescimento. Dessa forma, estudos com compostos, como beta-hidroxibutirato, e com substâncias, como probióticos e fitobioativos, mostraram-se promissores para efeito de antienvelhecimento buscado. No entanto, a falta de aceitação do processo natural do envelhecimento e as verdadeiras eficácia e seguridade da realização dessas intervenções na saúde transformam a ação interventiva em um constante estado de risco à saúde do indivíduo. Diante disso, este artigo, por meio de uma revisão de literatura dos últimos cinco anos (2018 a 2022), teve como objetivo analisar as possíveis relações existentes entre o processo de antienvelhecimento e os riscos relacionados à saúde, em adultos de 30 a 50 anos, a fim de esclarecer as dúvidas quanto à viabilidade dos procedimentos interventivos. Identificaram-se 20 artigos os quais revelaram que há, de forma evidente, aplicações médicas que podem ser utilizadas para o rejuvenescimento, porém, estas necessitam de certos cuidados e dosagens definidas para que sua eficácia seja, verdadeiramente, viável sem causar prejuízos à saúde e à vida humana.
Adesão farmacoterapêutica de idosos institucionalizados: uma revisão integrativa
Authors: Carmo João Victor Rezende do , Fernandes Stela Sofia Carvalho , Martins Marcelo Rodrigues , Batista Mariana Lopes Barros , Ferreira Beatriz Palladino , Silva Neto José Barbosa da , Lino Andressa Tassara , Vieira Renan Cezar , Matos Leonardo Patan de , Silva Cleiton Bueno da
Published: February 2023

O objetivo deste estudo foi avaliar os motivos que levam o idoso a não obter uma boa adesão terapêutica. Realizou-se uma revisão sistemática nas bases Medical Literature Analysis and Retrieval System Online (MEDLINE), Scientific Electronic Library Online (Scielo), Instituto Brasileiro de Geografia e Estatística (IBGE), Pubmed e Google Scholar no período de 2017 a 2022. Foram identificados trinta trabalhos, observando os critérios de inclusão e exclusão estabelecidos. A partir da leitura acerca do assunto abordado, foi possível constatar que a literatura sobre o tema em questão é homogênea, sendo um consenso de que a adesão terapêutica é baixa em idosos e, em especial, em idosos institucionalizados, relatando diversos fatores que contribuem para essa realidade, como a saúde psicológica do idoso, seu tempo de internação, relação com a família, dentre demais aspectos. A revisão de literatura ressalta que essa realidade necessita de mudanças a fim de futuramente observar boa adesão terapêutica.
Contribuições da enfermagem no processo de imunização da população: uma revisão de literatura
Authors: Pereira Gabriel Henrique , Monteiro Antônia Cristina Aguiar , Ferreira Valdiney Menezes , Martins Lusilene Nunes , Soares Luanna , Abreu Edielson de Jesus , Martins Cleudiane de Jesus Silva
Published: February 2023

Objetivo: Descrever as contribuições da enfermagem no processo de imunização da população. Trata-se de uma revisão integrativa da literatura, de cunho descritivo. Método: as fontes de pesquisas constituíram-se das bases de dados da Biblioteca virtual em Saúde (BVS), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Electronic Library Online (SciELO), MEDLINE e Google Acadêmico. A busca ocorreu no período de agosto de 2022 a janeiro de 2023. Os critérios de inclusão foram: estudos relacionados ao tema proposto, estando disponíveis nas bases de dados selecionadas de maneira integral, gratuita, nos idiomas português, espanhol e inglês, publicados entre 2013 a 2023.os critérios de exclusão utilizados: excluir estudos repetidos, incompletos e localizados em outros idiomas. Resultados: Os artigos apontam que as principais contribuições da enfermagem no processo de imunização da população estão relacionadas à educação em saúde, treinamento profissional e capacitação dos profissionais atuantes nas salas de vacina, gestão e gerenciamento de imunobiológicos, busca ativa de pacientes com esquema vacinal incompleto e oferta de imunizantes para a população. Conclusão: Mediante o que foi estudado, considera-se importante para o enfermeiro reconhecer os fatores que levam à não adesão à vacinação e suas consequências no âmbito populacional, bem como planejar e implementar condutas e estratégias adequadas de imunização para manter elevados os níveis de erradicação de patologias.
Aspectos epidemiológicos das internações por glaucoma no Brasil, entre 2012 e 2021
Authors: Marques Pablo Miranda Gomes , Lira Darlisson Soares de , D'Almeida Filho Luciano Feitosa , De Araújo Alves Marília , Bastos João Lucas Amorim , Silva José Claudio da , Coronado Bruno Nobre Lins
Published: February 2023

O glaucoma é uma doença neurodegenerativa com alta prevalência no Brasil, caracterizada por causar déficits progressivos no campo visual, sendo a cegueira uma consequência grave de seu diagnóstico tardio. Este estudo objetiva identificar os aspectos epidemiológicos das internações por glaucoma no Brasil, entre os anos de 2012 e 2021. Trata-se de um estudo epidemiológico descritivo, cujos dados foram obtidos por meio do Departamento de Informática do Sistema Único de Saúde (DATASUS), além de artigos científicos nas bases de dados PUBMED, SCIELO e GOOGLE ACADÊMICOS, referentes ao período de 2018 a 2023. Os dados obtidos pelo DATASUS foram reorganizados em quadros e analisados posteriormente. Visualizou-se que, nos últimos 10 anos, as internações de glaucoma no Brasil foram maiores na região Sudeste (45,72%), sendo a maioria dos atendimentos de caráter eletivo (78,75%). Em todos os anos, o número de internações foi mais prevalente nos homens, com a maior diferença no valor total entre os sexos em 2020 (14%). Em relação à faixa etária, houve predominância de hospitalizações em adultos entre 60-69 anos (29,32%). Além disso, a raça branca foi a de maior número de internações (50,76%). Portanto, os elevados achados no número de internações por glaucoma no Brasil demonstram a necessidade de intensificação das práticas de diagnóstico precoce, bem como intervenções terapêuticas adequadas, visando a preservação da saúde ocular.
Comprometimento pulmonar pelo paracoccidioides brasiliensis
Authors: Fonseca Caio César Jorge , Medeiros Lucca de Lima , Soares Romária Emanuela Carvalho Santos , Santos Ana Cristina Doria dos
Published: February 2023

Paracoccidioidomicose (PCM) é doença granulomatosa sistêmica que pode comprometer qualquer órgão, principalmente pulmões. O presente artigo tem por objetivo realizar uma revisão da literatura sobre o acometimento pulmonar na infecção por P. brasiliensis, abordando aspectos fisiopatológicos, os métodos diagnósticos e a conduta terapêutica mais adequada nesses casos. Este estudo baseia-se em uma revisão integrada da literatura, as bases utilizadas foram National Library of Medicine National Institutes of Health (PubMed), Biblioteca Virtual em Saúde (BVS/MEDLINE) e Science Direct, publicadas no período de 2017 a 2022. Um total de 1560 estudos foram identificados e 4 foram incluídos na análise final. Nos 4 artigos foi possível evidenciar que o diagnóstico precoce do comprometimento pulmonar na paracoccidioidomicose crônica traz benefícios para minimizar sequelas da doença. Todos os artigos citaram a correlação entre a paracoccidioidomicose crônica e o acometimento pulmonar. Dessa forma, foi possível observar que dentre os benefícios do diagnóstico precoce da paracoccidioidomicose está a diminuição das complicações pulmonares advindas da doença e com a diminuição da mortalidade da doença, assim como, a redução dos custos hospitalares.
Effective Breast Cancer Detection using Novel Deep Learning Algorithm
Authors: Buyung Irawadi , Munir Agus Qomaruddin , Wanda Putra
Published: February 2023

Ultrasound is one of the most common screening tools for breast cancer detection. However, the lack of qualified radiologists causes the diagnosis process to become a challenging task. Deep learning's promising achievement in various computer vision problems inspires us to apply the technology to medical image recognition problems. We propose a detection model based on the Rapid-CNN to detect breast cancer quickly and accurately. We conduct this experiment by collecting breast cancer datasets, pre-processing, training models, and evaluating the model performance. This model can detect breast cancer with bounding boxes based on the experiment result. In this model, it is possible to detect the bounding box that is more than what it should be, so we applied NMS  to eliminate the prediction of the bounding box that is less precise to increase accuracy.
Phenology, population size, and factors influencing variation in density of an endangered butterfly, the mottled duskywing Erynnis martialis
Authors: Demarse A , Trendos E , Linton J , Flockhart T , Brewster A , Keyghobadi N , Custode L , Norris DR
Published: February 2023

Understanding the natural history and ecology of endangered species is critical for developing effective, evidence-based conservation and management plans. The mottled duskywingErynnismartialisis a skipper butterfly inhabiting oak savanna, oak woodlands, alvars, and tallgrass prairie habitats containing their host plants,Ceanothusspp. Listed as endangered in Canada, few populations persist in Ontario and Manitoba, but there are no formal estimates of population size or what influences spatial variation in adult density, and we have limited knowledge of phenology. To address these knowledge gaps, we conducted spatially explicit mark-re-sighting over multiple years at 2 of the largest known populations in Ontario (specific locations withheld). Population sizes at Site A were estimated to be 1159 individuals (confidence limit [CL] = 845-1598) in 2021 and at Site B, 626 individuals (CL = 466-851) in 2020 and 2227 individuals (CL = 1110-4463) in 2021. Most (81%) re-sightings occurred within 5 d of marking, suggesting that adults likely live less than 1 wk. High densities of adults were generally associated with highCeanothusspp. abundance and open canopy, but relationships varied by site and year. Peak flight across sites and years ranged from 5-13 June. We recommend that existing and prospective habitat managers prevent succession with brush-cutting and/or prescribed burns, specifically in areas of abundantCeanothusspp. This work provides valuable information for future management and recovery efforts, including planned translocations to both historically occupied and newly restored sites.
From an Error Management Culture to Performance-An Empirical Study on the Influence of Motivation and Learning
Authors: Schlamann Hannah , Brandenberg Tammy , Marquardt Professor Dr. Nicki
Published: February 2023

For human beings, it is natural to conduct errors. Therefore, every company is confronted with erroneous actions that cannot be avoided. Several studies proved that managing errors and error consequences appropriately is indispensable. To ensure long-term benefits from errors, an organization needs to implement an error management culture (EMC). In this way, errors are collectively accepted and openly addressed. Research has been exploring how EMC results in increased performance. The current empirical study focuses on work motivation and informal workplace learning (IWL) that are assumed to mediate the relationship between EMC and performance. The purpose is to ex- plain this relationship with the help of both influencing factors. For this, an online survey was used to analyze the self-assessments of 186 employees from various companies and industries in Germany. The statistical results proved that companies with an EMC show elevated performance. Work motivation and IWL were found to partially mediate this relationship. More specifically, autonomous motivation, subsequent reflection as well as trial and application of own ideas were proven to be influencing factors. Building on the significant results, this study derives practical implications for organizations focusing on the design of an EMC while considering the three influencing factors. Future should dive deeper into the interaction between all these factors.
Aplikasi Monitoring kesehatan karyawan dan dosen untuk mencegah penyebaran Covid-19.
Authors: PURNOMO EKO
Published: February 2023

Mulai tahun 2019 dunia dilanda pandemic covid-19 termasuk Indonesia. Trend terkonfirmasi positif terus meningkat hingga awal januari 2021. Penyebaran cluster di tempat kerja termasuk salah satunya yang mendominasi, dimana banyak berkumpul pekerja dari berbagai daerah sehingga berpotensi menjadi pusat penyebaran, maka hal ini jika tidak dikendalikan penyebaran akan semakin massif. Pencegahan dan pengendalian ditempat kerja dapat dilakukan dengan memonitoring kesehatan karyawan setiap hari guna mengetahui tindakan yang harus dilakukan. Monitoring kesehatan karyawan dengan cara  mengetahui riwayat perjalanan, kondisi tubuh, dan penyakit penyerta. Monitoring kesehatan karyawan ini dapat memanfaatkan teknologi informasi melalui Aplikasi berbasis WEB dan internet. Aplikasi ini digunakan oleh dosen dan karyawan, aplikasi sudah menyediakan pertanyaan-pertanyaan pilihan tentang kondisi kesehatan terkait gejala covid, riwayat berpergian, paparan dan penyakit penyerta. Pertanyaan akan dibuat sesingkat mungkin dan Jawaban dari masing masing pertanyaan hanya terdapat 2 pilihan yaitu (“YA” dan “TIDAK”) sehingga tidak akan terlalu banyak memakan waktu untuk melakukan pengisiannya dengan harapan semua karyawan dpat melakukan pengisian secar konsisten.
CLUSTERING LOYALITAS PELANGGAN DENGAN MODEL RFM (REFENCY, FREQUENCY, MONETARY) DAN METODE K-MEANS BERBASIS MEDIAN
Authors: Supriadi Ahmad , Sukron Moh. , Faid Mochammad
Published: February 2023

Data loyalitas pelanggan dalam dunia jual beli selalu bertambah seiring dengan berjalannya waktu. Perkembangan teknologi yang sangat pesat dalam dunia bisnis perdagangan menjadi arah perubahan yang sangat signifikan dalam proses transaksi jual beli dengan pemanfaatan tekonologi proses transaksi penjualan dapat dijadikan sebuah sekumpulan data besar dan melimpah, Hal ini berpeluang untuk dapat dilakukan proses pengolahan data sehingga akan didapat sebuah informasi yang bermanfaat. Informasi tersebut seperti mengenai pengelompokan data pelanggan yang memiliki loyalitas tinggi sehingga pihak unit usaha terkait dapat memberikan reward pada pelanggan yang memiliki tingkat loyalitas tinggi. Untuk mengetahui hal tersebut, dilakukan  pengujian  model  dengan  menggunakan  metode k-means dengan pemilihan  pusat  klaster  awal  berbasis  median, hasil eksperimen dengan model tersebut dapat menghasilkan kualitas klaster yang lebih baik karena dengan pemilihan pusat klaster awal berbasis median tidak terjadi klaster kosong. Klaster yang dihasilan yaitu pada cluster pertama 133 cluster Kedua 30 dan cluster ketiga 208 sedangkan cluster keempat 129 dengan nilai DBI 0,694. Sedangkan metode k-mmeans dengan pemilihan pusat klaster standart didalam experimen ini menggunakan tool rapidminer didapat cluster pertama 310 cluster Kedua 19 dan cluster ketiga 37 sedangkan cluster keempat 134 dengan nilai DBI 0,807.
Implementasi Data Mining Dalam Menentukan Strategi Promosi Program KB Menggunakan Algoritma K-Means Clustering
Authors: Hasyim Fuadz , Muafi Muafi
Published: February 2023

Strategi promosi program KB yang dilakukan oleh pihak Badan Kependudukan dan Keluarga Berencana Nasional (BKKBN) melalui Balai Penyuluhan Program Keluarga Berencana (BPPKB) masih menyamaratakan seluruh daerah tanpa melihat keberhasilan program KB. Dibutuhkan analisis data agar strategi yang dilakukan bisa tepat sasaran. Data yang akan dianalisis merupakan data rekapitulasi kependudukan yang ada pada BPPKB. Untuk menganalisis data tersebut dibutuhkan metode atau teknik analisis data yang tepat yaitu dengan analisis data mining menggunakan algortima k-means clustering. Dengan cara melihat pola keterkaitan antar data yang digunakan sebagai penentu keberhasilan program KB, pihak BPPKB dapat dengan mudah dalam menentukan strategi promosi program KB hanya melihat pola data dari masing-masing klaster. Data penelitian diambil dari BPPKB Kecamatan Gading untuk data peserta KB aktif tahun 2019-2021, yang mencakup data dari 19 Desa di wilayah Kecamatan Gading Kabupaten Probolinggo. Dari hasil penelitian yang telah dilakukan didapatkan kesimpulan bahwa strategi promosi terbaik bagi calon peserta KB baru agar tepat sasaran adalah dengan mengirim tim admisi BPPKB yang sesuai dengan program KB yang paling banyak diminati dan melakukan promosi berdasarkan wilayah peserta KB baru dengan melakukan penyelarasan menggunakan promotion mix.
Penerapan Data Mining Dengan Metode Association Rule Mining Untuk Memprediksi Minat Belajar Bahasa Arab Di Lembaga Awwaliyah Al-Hasyimiyah
Authors: Pawening Ratri Enggar
Published: February 2023

Pendidikan Bahasa Arab saat ini sudah banyak dipelajari diberbagai tingkatan pendidikan, terutama di lingkungan pesantren yang sebagian besar mewajibkan santri untuk berbahasa arab setiap harinya. Di Wilayah Al-Hasyimiyah Nurul Jadid sendiri, ada beberapa lembaga yang mempelajari Bahasa Arab, salah satunya adalah Lembaga Awwaliyah yang berada dibawah naungan wilayah Al-Hasyimiyah. Selain melakukan kegiatan belajar dan penyetoran mufrodat, para santri juga akan melakukan ujian akhir untuk melihat sistem pembelajaran di lembaga, karena nilai santri menjadi salah satu tolak ukur penguasaan materi pelajaran oleh santri. Nilai santri juga menjadi acuan untuk pengambilan keputusan kelulusan. Dalam belajar Bahasa Arab pun dapat dilihat dan dibedakan santri yang mempunyai minat belajar dengan santri yang tidak memiliki minat belajar. Salah satu contoh santri yang memiliki minat belajar adalah mereka akan senang mempelajari dan menambah kosakata Bahasa Arab, aktif pada saat pembelajaran, dan medapatkan nilai ujian akhir yang baik, sedangkan mereka yang tidak mempunyai minat akan merasa malas dan bosan untuk belajar. Dengan memanfaatkan pengetahuan data mining, data-data santri dan kegiatan belajar yang sudah disimpan di lembaga dapat diolah lebih lanjut untuk membantu lembaga menemukan hal-hal yang bisa dimaksimalkan untuk pengingkatan kualitas pembelajaran. Pada penelitian ini metode yang digunakan adalah Association Rule Mining (ARM) dengan algoritma apriori. Tahapan penelitian yang dilakukan adalah pengumpulan data, pembersihan dan transformasi data, analisis aturan, dan interpretasi hasil. Dari hasil pengujian diperoleh kesimpulan adalah meskipun seluruh variabel yang mempengaruhi minat belajar ditentukan secara apriori, dapat ditunjukkan bahwa ada hubungan asosiatif antara variabel nilai mingguan dengan variabel nilai setoran, nilai akhir, dan rekap absen.
Implementasi Algoritma C4.5 Untuk Memprediksi Kesesuaian Gaya Belajar Siswa Sekolah Dasar
Authors: Sudriyanto Sudriyanto , Listrianti Feriska , Jamal Jamal
Published: February 2023

Data Mining adalah proses mengekstraksi dan menemukan pola dalam kumpulan data besar yang melibatkan metode dalam proses  pembelajaran mesin, statistik, dan sistem basis data. SD Negeri Sidodadi Paiton merupakan sekolah dasar yang terletak di desa Sidodadi kecamatan paiton. Pada proses pembelajaran di SD Negeri Sidodadi, masih banyak murid yang tidak fokus dan tidak memiliki kemauan untuk belajar, kemungkinan terbesar adalah ketidak cocokan gaya belajar dan metode belajar guru tersebut. Oleh karenanya, penulis melakukan analisis data mining terhadap data murid dan kepribadiannya agar data tersebut dapat berubah menjadi informasi yang bermanfaat bagi lembaga. Informasi ini bisa membantu untuk meningkatkan proses belajar mengajar di SD Negeri Sidodadi Paiton. Penulis menggunakan hasil data quisioner terhadap siswa kelas 4, 5 dan 6 sebanyak 165 data siswa-siswi yang telah penulis sajikan. Dalam proses analisis ini, penulis menggunakan tools Rapiminer Studio. Metode yang digunakan decision tree dengan algoritma C4.5. Hasil prediksi menggunakan algoritma decision tree C4.5 dengan hasil 8 rules. Persentasi hasil akurasi decision tree dengan menggunakan menggunakan 10 Fold Cross Validation  membuktikan bahwa tingkat akurasinya sebesar 81.18%. dengan nilai class precission untuk prediksi kinestetik sebesar 85.43%, prediksi visual sebesar 33.33%, dan prediksi auditorial sebesar 0.00%, hasil 5 Fold Cross Validation akurasinya sebesar 82.27%. dengan nilai class precission untuk prediksi kinestetik sebesar 86.09%, prediksi visual sebesar 41.67%, dan prediksi auditorial sebesar 0.00%. Dari hasil perbandingan membuktikan implementasi dengan model 5 Fold Cross Validation lebih baik.
Rancang Bangun Auto Control Penerangan Jalan Umum (PJU) dengan Menggunakan Real Time Clock & Light Dependent Resistor Mikrokontroler di Pondok Pesantren Nurul Jadid
Authors: Rahim Abdul
Published: February 2023

Pondok Pesantren Nurul Jadid yang bertempat di Desa Karanganyar Kecamatan Paiton Kabupaten Probolinggo Jawa Timur, masih menggunakan saklar manual sehingga mengalami kesulitan di saat menghidupkan dan mematikan lampu jalan yang jaraknya lumayan jauh dari titik satu dengan titik yang lainnya, dan juga sering lupa menghidupkan dan mematikan lampu. Dari alat ini masing-masing sensor berfungsi saling berkaitan dan saling mendukung satu sama lain sehingga menjadi satu-kesatuan alat yang bisa di terapkan di Pondok Pesantren Nurul Jadid, sehingga menjadi lebih mempermudah petugas PLNJ dan lampu berfungi sesuai dengan fungsinya segingga lebih efisiensi dalam penggunaan. Untuk menghasilkan sistem monitoring penggunaan Penerangan Jalan Umum (PJU) di wilayah Pondok Pesantren Nurul Jadid, maka tujuan dari penelitian ini adalah agar bagian perlengkapan PLNJ lebih mudah dalam mengontrol lampu Penerangan Jalan Umum (PJU). Dari hasil implementasi bahwasanya alat yang digunakan bisa mempermudah dalam pengoperasian untuk mengontrol penerangan jalan umum, dan juga bisa menggunakan tiga jenis pengaturan yaitu dengan RTC, LDR, Manual
The ‘Myth’ of Beaumont-Hamel: Counter-Monumentality and Newfoundland Identity in Edward Riche's Dedication
Authors: White Bonnie
Published: February 2023

The First World War has had an indelible impact on Newfoundland, shaping not only its relationship with Britain and empire, but also its union with Canada in 1949. For some, the Battle of the Somme was a powerful display of Newfoundland's identity as a British dominion and its loyalty to the mother country. Many Newfoundlanders, however, lament the tragic economic and political consequences of Newfoundland's war service that many believe led to its loss of independence and its union with Canada decades later. Edward Riche's 2017 play Dedication explores the legacy of the First World War on Newfoundland identity and the province's continued positive association with Sir Douglas Haig through the dramatisation of a grieving female journalist interviewing Haig in St. John's in 1924, just before the unveiling of the national war memorial. The play grapples with themes of colonisation, patriotism, and duty as the playwright seeks to challenge the prevailing myth of identity grounded in glorious sacrifice. While the interview in the play raises questions about the war's legacy through its focus on the dedication of the WWI monument by Haig himself, Riche interrogates Newfoundland's established memory of the war, as well as the value of monuments as historical markers of memory and identity.
Samstarf Landsvirkjunar og Jarðvísindastofnunar Háskólans um jöklarannsóknir 1978 til 2022 (Glaciological research 1978–2022)
Authors: Pálsson Finnur , Björnsson Helgi , Haraldsson Hannes H.
Published: February 2023

Samstarf Landsvirkjunar (LV) og jöklahóps Raunvísindastofnunar (RH) og síðar Jarðvísindastofnunar Háskólans (JH), hefur staðið í nærri fjóra áratugi, og á margan hátt lagt grunn að alhliða og sértækri þekkingu á jöklum Íslands, eðli þeirra, stærð og langtíma breytingum. Við upphaf þessa samstarfs um miðjan áttunda áratug 20. aldar var þekking á jöklum landsins mjög takmörkuð. Flatarmál jöklanna var sæmilega þekkt en hæð þeirra og lögun síður og ísþykkt aðeins í stöku punktum frá því jarðsveiflumælingar höfðu verið gerðar um miðja 20. öld. Hæðarlínur á landakortum voru enn þær sömu og dregnar voru á kort Dana og Bandaríkjamanna skömmu fyrir og eftir seinni heimsstyrjöld. Fyrir ofan 1000 m hæð höfðu kortin reyndar aldrei sýnt annað en grófar ágiskanir um hæð og lögun yfirborðs. Jaðrar jöklanna höfðu þó öðru hvoru verið endurskoðaðir þegar kort voru endurprentuð, en þó sjaldan svo að greinilega kæmi fram frá hvaða tíma nýr jaðar væri. Eftir 1970 voru síðan gerð kort af blásporðum nokkurra skriðjökla með nákvæmum landmælingum, ýmist á vegum LV eða Raforkumálastjóra (síðar Orkustofnunar). Meðalþykkt jökuls hafði þá einnig verið metin með þyngdarmælingum á nokkrum sniðum á Vatnajökli. ...
ASPECTOS CONSTRUTIVOS E PROJETUAIS DE EDIFÍCIO PAULISTANO DOS ANOS DE 1970
Authors: Hayashi Juliana Naomi , Freitas Márcia Regina de
Published: February 2023

Na cidade de São Paulo (SP), a construção civil de edifícios residenciais de múltiplos pavimentos intensificou-se na década de 1930, com estruturas de concreto armado e alvenaria de vedação. Esse processo construtivo se mantém majoritário nos edifícios paulistanos, ocorrendo, contudo, modificações nos aspectos construtivos e projetuais. Neste artigo, um edifício construído em 1973 foi selecionado como objeto de estudo. Essa escolha foi motivada pela sua construção ter ocorrido em um período anterior às novas normas e códigos de obras elaborados após as tragédias de incêndios nos Edifícios Andraus e Joelma, em 1972 e 1974, respectivamente. A partir da análise evolutiva, conclui-se que novas técnicas surgiram para promover a industrialização de processos artesanais, garantir a manutenibilidade dos subsistemas, inserir o fator sustentabilidade, aumentar a segurança e aplicar ou criar novos equipamentos, ferramentas e materiais desenvolvidos entre as décadas de 1980 e 2010, na construção de edifícios residenciais.
INVOCAÇÃO PEDAGÓGICA NO ENSINO MÉDIO: O estado da arte
Authors: Mendanã Denise Teberga , Domingos Silvio Duarte , Chamon Edna Maria Querido de Oliveira , Santana Leonor M
Published: February 2023

Esse artigo tem por objetivo refletir sobre as políticas públicas e as práticas pedagógicas inovadoras para o Ensino Médio. Para tanto, realizou-se pesquisa de caráter bibliográfico e exploratório, buscando identificar os elementos que permeiam essa discussão. Para o levantamento das obras, foram consultadas bases de dados nacionais e internacionais, utilizando-se como termos indutores, “Ensino Médio” e “inovação pedagógica”. Os dados foram analisados a partir da Análise de Conteúdo de Bardin (2012). Identificou-se 37 trabalhos, entre teses, dissertações, artigos, trabalhos publicados em anais de eventos e capítulos de livros. Eles foram categorizados em três grupos, (i) políticas públicas e currículo, (ii) práticas educativas, incluindo o uso de recursos tecnológicos digitais e (iii) formação de professores. Conclui-se que a inovação exige mudança de postura do professor, rompendo com paradigmas tradicionais e, seja fortalecida com uma formação de professores eficaz e políticas públicas condizentes com os contextos escolares.
INOVAÇÕES PEDAGÓGICAS E CONCEITOS DA EDUCAÇÃO 4.0
Authors: Souza Mariana Aranha de , Oliveira Stenio Augusto de
Published: February 2023

Este artigo tem por objetivo compreender se há elementos constituintes de inovações pedagógicas relacionadas à Educação 4.0 nas Escolas Militares e, em havendo, como isso ocorre. De natureza quali-quantitativa, esta pesquisa tem como participantes 288 professores, sendo 39 da AMAN e 249 dos Colégios Militares do Brasil. Tem-se como instrumentos de coleta de dados um questionário online, elaborado na plataforma Google Forms, que foi enviado para os docentes de forma online, entrevistas semiestruturadas individuais, realizadas de forma presencial e pesquisa documental. Os dados, coletados no ano de 2020, foram analisados por meio da técnica da Análise de Conteúdo. Os resultados permitiram uma reflexão importante sobre inovações pedagógicas, mídias e Educação 4.0, a partir do apontamento de que as inovações acontecem na medida em que há um processo formativo pessoal e institucional constante. Observou-se uma tendência à diminuição de aulas expositivas e ao aumento de estratégias mais colaborativas, como problematizações e projetos, incluindo diferentes tecnologias e mídias digitais, inclusive o AVA. Para o grupo pesquisado, a inovação e a gestão das práticas apresentam relação direta com as metodologias empregadas durante o processo educacional.
RELAÇÕES UNIVERSIDADE-EMPRESA E INOVAÇÃO EM UM CONSELHO EMPRESARIAL
Authors: Guedes Matheus , Ávila Maria Auxiliadora , Monteiro Patricia Ortiz
Published: February 2023

O Conselho Empresarial do Sul de Minas (CESUL) é um órgão colegiado de empresários, independente, não governamental e não político, coordenado pelo Grupo Educacional UNIS, instituição de ensino superior, com sede em Varginha-MG. Para fins deste artigo, buscou-se analisar, no âmbito da relação Universidade - Empresa (U-E) e mediante pesquisa qualitativa, as ações de inovação geradas e decorrentes da participação dos empresários no CESUL. Foi realizada análise documental mediante consulta às atas, comunicados, registros eletrônicos e notícias divulgadas pela Comunicação Interna do UNIS. Foram, também, entrevistados 7 membros do CESUL. Os dados narrativos, registrados por meio das entrevistas, foram transcritos, organizados em quadros síntese e analisados vertical e horizontalmente. Parece pertinente afirmar que o CESUL tem um papel importante na formação, orientação ou atualização dos executivos que o compõem - e que esses conselheiros são responsáveis por parte considerável dos ativos financeiros e humanos da região. Também, fica evidente que o CESUL é um agente de articulação de iniciativas que fazem convergir os esforços dos poderes governamentais, empresariais e universitários - e colocam esse tríplice hélice regional em movimento, a fim de prover soluções de impacto positivo e inovador na sociedade.
ESTRESSE EM PROFISSIONAIS DE ENFERMAGEM EM TEMPOS DA COVID-19
Authors: Dos Santos Feitosa Marcelo , M Santana Leonor , Maria Querido de Oliveira Chamon Edna
Published: February 2023

Nesse cenário de transformações causadas pela pandemia da covid-19 no ambiente de trabalho, tem-se o objetivo de investigar o estresse nos profissionais de enfermagem de um hospital, bem como identificar as manifestações de estresse físico, psíquico, psicofisiológico e de temporalidade. Trata-se de uma pesquisa exploratória, com abordagem de natureza quantitativa e amostragem por resposta voluntária. A amostra é de 312 profissionais de enfermagem. Para avaliar o nível de estresse dos participantes da pesquisa, utilizou-se a escala toulousaine de estresse. Os resultados indicaram índices de estresse acima da média nacional, para estresse físico e global. Pode-se concluir que os profissionais de enfermagem precisam de atenção primordial por parte das organizações de saúde, por estar frente a uma atividade laboral altamente crítica (potencializada pela pandemia da covid-19) e relacionada com sofrimentos psíquico e físicos constantemente marcados por incertezas do setor.
Anesthetic implications in porphyrias
Authors: Randjelovic Milica , Stojanovic Milena , Radeka Jovan , Vasilijic Milena , Jankovic Radmilo
Published: February 2023

The porphyrias are a group of disorders related to deficient heme biosynthesis, caused by malfunction of certain enzymes in the synthesis pathway. Erythropoietic porphyrias present with cutaneous symptoms and do not affect the nervous system. Hepatic porphyrias develop acute attacks with mild to severe neurovisceral symptoms, dramatic course, and rare, but possibly lethal outcomes. Anesthetic management of patients suffering from hepatic porphyria is challenging regarding the possibility of triggering or worsening the acute attack with medications that induce or maintain anesthesia. The medications are labeled as safe or unsafe according to laboratory experiments, clinical studies, case reports and experience. In this paper, we discuss underlying pathophysiology, presentation, therapy recommendations and anesthetic implications related to porphyrias.
Evaluating the biomechanical performance of Ti6Al4V volar plates in patients with distal radius fractures
Authors: Li Hua , Wang Daofeng , Zhang Wupeng , Xu Cheng , Xiong Dou , Li Jiantao , Zhang Licheng , Tang Peifu
Published: February 2023

Purpose: This study aimed to investigate the biomechanical performance of three Ti6Al4V volar plates with the latest designs using a finite element model.

Methods: An AO type 23-A3 distal radius fracture and the models of T plate (2.4 mm LCP Volar Distal Radius Plate), V plate (2.4 mm LCP Two-Column Volar Distal Radius Plate) and π Plate (2.4 mm Volar Rim Distal Radius Plate) (all from Depuy Synthes, West Chester, PA, USA, Ti6Al4V) were built in 3D-matic software. After assembling the internal fixation and fractures, we imported these models into the finite element analysis software (ABAQUS). An axial loading of 100 N was added to the distal end of each model. The displacements of total models and implants, the principal strains and the von Mises stresses in the plates were calculated and compared to capture the biomechanical features of the three plates.

Results: The T plate, V plate and π plate represented a model displacement of 0.8414 mm, 1.134 mm and 1.936 mm, respectively. The T plate was with the implant displacement of 0.7576 mm, followed by the V plate (0.8802 mm) and the π plate (1.545 mm). The T plate had the smallest principal strain of 0.23%, the V plate showed an intermediate level of 0.28%, and the π plate had a value of 0.72%. The least peak von Mises stress was observed in the V plate with 263.6MPa, and this value was 435.6 MPa and 1050 MPa in the T plate and π plate, respectively.

Conclusion: The biomechanical features of three Ti6Al4V volar locking plates in an AO type 23-A3 fracture were described in our analysis. The T plate and the V plate showed similar biomechanical performance while the π plate represented worse performance than the other two plates.
An overview of blockchain efficient interaction technologies
Authors: Liu Feng , He Sihao , Li Zhenghao , Li Zhibin
Published: February 2023

The successful operation of Bitcoin has made its underlying blockchain technology receive wide attention. As the application scenarios of blockchain technology are enriched, the requirements for its performance are getting higher. Therefore, it is of utmost importance to effectively solve the problem of high-performance data interaction in the blockchain. In this paper, based on relevant domestic and foreign research literature, we start from the development history of blockchain technology and review the relevant research work on improving the performance of blockchain from three perspectives: on-chain interaction technology, off-chain interaction technology, and cross-chain interaction technology in turn. The on-chain and off-chain interaction technologies improve performance by improving the architecture of the blockchain system. The performance improvement solution of on-chain interaction technology is to modify and optimize the basic protocol and architecture of the blockchain itself to achieve a performance improvement. Still, the impact of this approach is limited in terms of performance improvement. The performance improvement solution of off-chain interaction technology is to transfer part of the data processing to off-chain and only return the final result to on-chain for storage and recording, which reduces the burden of on-chain operation and improves the efficiency of data processing. In terms of cross-chain interaction technology, this paper analyses four mainstream technology, namely, Notary Scheme, Side chain and Chain relay, Hash-Locking, and Distributed Private Key Control, and ultimately concludes through comparative analysis that cross-chain technology has a significant impact on improving blockchain performance. Finally, the paper provides a systematic overview of the above and an outlook on the possible future development of technologies related to enhancing blockchain performance.
Updated perspective of EPAS1 and the role in pulmonary hypertension
Authors: Wang Na , Hua Jing , Fu Yuhua , An Jun , Chen Xiangyu , Wang Chuancui , Zheng Yanghong , Wang Feilong , Ji Yingqun , Li Qiang
Published: February 2023

Pulmonary hypertension (PH) is a group of syndromes characterized by irreversible vascular remodeling and persistent elevation of pulmonary vascular resistance and pressure, leading to ultimately right heart failure and even death. Current therapeutic strategies mainly focus on symptoms alleviation by stimulating pulmonary vessel dilation. Unfortunately, the mechanism and interventional management of vascular remodeling are still yet unrevealed. Hypoxia plays a central role in the pathogenesis of PH and numerous studies have shown the relationship between PH and hypoxia-inducible factors family. EPAS1, known as hypoxia-inducible factor-2 alpha (HIF-2α), functions as a transcription factor participating in various cellular pathways. However, the detailed mechanism of EPAS1 has not been fully and systematically described. This article exhibited a comprehensive summary of EPAS1 including the molecular structure, biological function and regulatory network in PH and other relevant cardiovascular diseases, and furthermore, provided theoretical reference for the potential novel target for future PH intervention.
Chlamydia trachomatis induces the transcriptional activity of host YAP in a Hippo-independent fashion
Authors: Caven Liam T. , Brinkworth Amanda J. , Carabeo Rey A.
Published: February 2023

Introduction

The obligate intracellular pathogen Chlamydia trachomatis is the causative agent of the most common bacterial sexually transmitted disease worldwide. While the host response to infection by this pathogen has been well characterized, it remains unclear to what extent host gene expression during infection is the product of Chlamydia-directed modulation of host transcription factors.

Methods

To identify transcription factors potentially modulated by Chlamydia during infection, we infected immortalized endocervical epithelial cells (End1/E6E7) with the anogenital C. trachomatis serovar L2, harvesting polyadenylated RNA for bulk RNA-sequencing. Subsequent experiments elucidating the mechanism of infection-mediated YAP activation assayed YAP target gene expression via qRT-PCR, YAP nuclear translocation via quantitative immunofluorescence, and YAP phosphorylation via Western blotting.

Results

RNA sequencing of Chlamydia-infected endocervical epithelial cells revealed gene expression consistent with activity of YAP, a transcriptional coactivator implicated in cell proliferation, wound healing, and fibrosis. After confirming induction of YAP target genes during infection, we observed an infection-dependent increase in YAP nuclear translocation sensitive to inhibition of bacterial protein synthesis. While Hippo-mediated phosphoinhibition of YAP at S127 was unaffected by C. trachomatis infection, Hippo-independent phosphorylation at Y357 was increased. Infection did not enhance nuclear translocation of Y357F mutant YAP, illustrating a requirement for phosphorylation at this residue. Pharmacological inhibition of host Src-family kinase activity attenuated YAP Y357 phosphorylation, but not nuclear translocation – which was instead sensitive to inhibition of Abl.

Discussion

Our results define a transcriptome-altering mechanism of pathogen-directed YAP activation that bypasses canonical inhibition by the Hippo kinase cascade, with a potential link to chlamydial fibrosis and other advanced disease sequelae. Additional study is required to determine the specific role of infection-associated Y357 phosphorylation and Abl activity in chlamydial induction of YAP.
Spatiotemporal heterogeneity and impact factors of hepatitis B and C in China from 2010 to 2018: Bayesian space–time hierarchy model
Authors: Qian Jiaojiao , Yue Ming , Huang Peng , Ai Lele , Zhu Changqiang , Wang Chongcai , Luo Yizhe , Yue Na , Wu Yifan , Zhang Yun , Wang Chunhui , Tan Weilong
Published: February 2023

Introduction

Viral hepatitis is a global public health problem, and China still faces great challenges to achieve the WHO goal of eliminating hepatitis.

Methods

This study focused on hepatitis B and C, aiming to explore the long-term spatiotemporal heterogeneity of hepatitis B and C incidence in China from 2010 to 2018 and quantify the impact of socioeconomic factors on their risk through Bayesian spatiotemporal hierarchical model.

Results

The results showed that the risk of hepatitis B and C had significant spatial and temporal heterogeneity. The risk of hepatitis B showed a slow downward trend, and the high-risk provinces were mainly distributed in the southeast and northwest regions, while the risk of hepatitis C had a clear growth trend, and the high-risk provinces were mainly distributed in the northern region. In addition, for hepatitis B, illiteracy and hepatitis C prevalence were the main contributing factors, while GDP per capita, illiteracy rate and hepatitis B prevalence were the main contributing factors to hepatitis C.

Disussion

This study analyzed the spatial and temporal heterogeneity of hepatitis B and C and their contributing factors, which can serve as a basis for monitoring efforts. Meanwhile, the data provided by this study will contribute to the effective allocation of resources to eliminate viral hepatitis and the design of interventions at the provincial level.
Cre-loxP-mediated genetic lineage tracing: Unraveling cell fate and origin in the developing heart
Authors: Wang Tao , Chen Xinzhe , Wang Kai , Ju Jie , Yu Xue , Wang Shaocong , Liu Cuiyun , Wang Kun
Published: February 2023

The Cre-loxP-mediated genetic lineage tracing system is essential for constructing the fate mapping of single-cell progeny or cell populations. Understanding the structural hierarchy of cardiac progenitor cells facilitates unraveling cell fate and origin issues in cardiac development. Several prospective Cre-loxP-based lineage-tracing systems have been used to analyze precisely the fate determination and developmental characteristics of endocardial cells (ECs), epicardial cells, and cardiomyocytes. Therefore, emerging lineage-tracing techniques advance the study of cardiovascular-related cellular plasticity. In this review, we illustrate the principles and methods of the emerging Cre-loxP-based genetic lineage tracing technology for trajectory monitoring of distinct cell lineages in the heart. The comprehensive demonstration of the differentiation process of single-cell progeny using genetic lineage tracing technology has made outstanding contributions to cardiac development and homeostasis, providing new therapeutic strategies for tissue regeneration in congenital and cardiovascular diseases (CVDs).
Geodetic residual time series: A combined series by minimization of their internal noise level
Authors: Wińska Małgorzata
Published: February 2023

This study aims to assess the hydrological effects of polar motion calculated from different combinations of geophysical excitations at decadal, seasonal, and non-seasonal periods. The geodetic residuals GAO, being a difference between observed geodetic excitation function of polar motion Geodetic Angular Momentum (GAM) and atmospheric (Atmospheric Angular Momentum—AAM) plus oceanic excitation functions (Oceanic Angular Momentum—OAM), are compared. Estimating hydrological effects on Earth’s rotation differs significantly, especially when using various oceanic models. Up to now, studies of geophysical excitations of polar motion containing AAM, OAM, and hydrological angular momentum (HAM) have not achieved entire agreement between geophysical (sum of AAM, OAM, and HAM obtained from the models) and geodetic excitation. Many geophysical models of the atmosphere, oceans, and land hydrology can be used to compute polar motion excitation. However, these models are very complex and still have uncertainties in the process descriptions, parametrization, and forcing. This work aims to show differences between various GAO solutions calculated from different mass and motion terms of various AAM and OAM models. Justifying to use one combination of GAO to estimate geodetic residuals is comparing those time series to hydrological excitations computed from Gravity Recovery and Climate Experiment (GRACE) data and the Land Surface Discharge Model (LSDM) model. Especially the quality of each geodetic residual time series is determined by estimating their noise level using a generalized formulation of the “three-cornered hat method” (3CH). This study presents a combined series of geodetic residuals GAO in polar motion (PM), wherein the internal noise level is shortened to a minimum by using the 3CH method. The combined GAO time series are compared with results obtained from the GRACE/GRACE Follow-On (GRACE-FO) solution provided by International Combination Service for Time variable Gravity Fields (COST-G) and the single solution elaborated by the Center for Space Research (CSR) and from the HAM LSDM hydrological model. The results show that higher consistency between GAO and HAM excitations can be achieved by minimizing the internal noise level in the GAO combined excitation series using the 3CH method, especially for the overall broadband and seasonal oscillations. For seasonal spectral bands, an agreement between combined GAO and the best-correlated series of GRACE CSR achieve correlations as high as 0.97 and 0.83 for the χ1 and χ2 equatorial components of PM excitation, respectively. This study’s combined geodetic residual time series slightly improved consistency between observed geodetic polar motion excitations and geophysical ones.