bluuebunny/crossref_metadata_2025 huggingface dataset:
关于煤矿地测防治水工作管理的思考
Authors: 曹 晓源
Published: March 2020

近些年来,我国煤矿生产安全事故常有发生,不但造成了经济损失,也直接威胁到工人的生命安全。而引发煤矿生产安全事故的一大要素就是地测防治水工作缺少针对性、完善性,所以重点研究煤矿地测防治水工作管理具有现实意义。
现代测绘基准在金矿地质勘查测量中的应用
Authors: 谷 大鹏
Published: March 2020

地质勘查工作可应用于生产建设的各个方面,对经济发展起到了极大的带动作用。同时此项工作比较复杂,其勘查结果会受到多重因素的共同影响。由于测量区域内的环境一般较为恶劣,致使在测量过程中往往会面临各种困难。尤其在金矿地质勘查测量中,因金矿分布的不均衡性,使得工作往往难以开展。因此应重视应用现代测绘基准,从而提高勘察测量的准确性,进而保障金矿开采工作的稳定进行。本文分析了现代测绘基准在金矿地质勘查测量中的应用。
西藏浅成低温金-银矿的成矿条件与可能产出区分析
Authors: 欧 长焱
Published: March 2020

在2014年,我国西藏地区发现了浅成低温金-银矿床,彻底结束了西藏没有典型浅成低温热液矿床的历史,同时也进一步完善了特提斯成矿带的成矿作用。基于此,本文结合理论实践,在简要阐述浅成低温热液矿床特点的基础上,分析了具体的成矿条件,并分析了可能产出区。分析结果表明,西藏发现了浅成低温热液矿床,且深部为斑岩型矿体,二者共同形成了一套完善的浅成低温热液矿床成矿系统,是我国目前最大的浅成低温金-银矿。
无人机倾斜摄影测量在矿山测绘中的实际运用分析
Authors: 杨 兵
Published: March 2020

在无人机倾斜摄影领域,由于其采集数据方式范围广、精度高、分辨率高等种种优点,已经在测绘领域广泛开展应用,并应用于许多复杂场景,均取得了不错的效果。文章基于煤矿测绘中的无人机应用,论述倾斜摄影测量技术,探讨相关措施与工艺,提出几点意见和建议,以供参考。
关于找矿地质勘探技术创新的探索
Authors: 汤 丽莎
Published: March 2020

本文主要对地质勘探工作的定义和作用展开研究,之后对地质勘探在找矿工作中的应用进行研究,对地质勘探找矿内容进行论述。在当前社会发展水平全面提升背景下,各行业都得到了较大程度的发展,而矿业作为我国国民经济的基础组成,不仅关系着我国经济命脉,同时和群众生产生活的联系也十分紧密。所以在此种情况下如何加强矿业发展,引起国家和关注,地质勘探在找矿工作中的作用就尤为关键。为此,本文将详细阐述相关问题,希望和同行业工作人员展开深入交流。
岩土工程地质灾害防治技术及其策略分析
Authors: 杨 俊岭 , 赵 朕 , 崔 晓亮
Published: March 2020

在岩土工程项目建设中,地质灾害与地理环境、地质构造、气候环境之间的联系十分密切,人为因素是岩土工程地质灾害防治的主要影响因素之一,尤其在工程类活动中,增加了地质灾害的发生率,文章主要对岩土工程地质灾害防治技术及其策略进行了研究。
卫星遥感影像处理技术分析
Authors: 周 玉秀 , 申 忠昌
Published: March 2020

卫星遥感影像技术的发展和人们实际生活密切相关,遥感影像的本质是一种能够反映地物目标电磁辐射特性的能量分布图,能够在同一个空间位置上获取不同波段、不同时间变化的遥感图像,从而为相关人员识别和区分不同地物、提取各类信息提供有力支持。
关于黄土地区黄土湿陷性浅析
Authors: 朱 彦冰
Published: March 2020

近些年来我国经济建设不断发展,黄土地区建设质量的要求不断提高,尤其是对提高稳定性要求更高。对于湿陷性黄土地区,采取科学合理的处治措施解决施工中存在的问题对整个黄土地区工程的建设质量具有重要意义。本文对湿陷性黄土地区的判定和处理措施进行总结,以便更好地解决湿陷性黄土地区问题,确保其质量。
基于ArcGIS Runtime的便携式城市地下空间信息管理系统设计与实现
Authors: 杨 志刚 , 贺 成梅
Published: March 2020

随着中国经济高速发展,各地面临着人口密集、交通堵塞、能源消耗增大、房价上涨等诸多问题,城市空间需求急剧膨胀与地面空间有限这一矛盾也日益突出,有效地开发利用地下空间越来越迫切。近年来,全国各地在不断的发展利用城市地下空间资源,向地下要资源,是目前多数城市解决用地紧张的重要途径。但是地下空间的开发利用具有不可逆性的特点,在进行地下空间开发利用前,充分的了解既有的地下空间利用现状情况是避免城市地下空间盲目开发的前提条件。本文的研究旨在收集历史各时期地下空间利用的资料的基础上,利用信息技术手段建立便携式地下空间信息综合管理平台,为地下空间开发利用的科学性、合理性提供基础保障。
探讨基础测绘对数字城市建设的影响和应用策略
Authors: 郭 江萍
Published: March 2020

基于基础测绘对数字城市建设的影响和应用策略研究,掌握测绘对数字城市建设概念及作用,结合基础测绘存在的问题,得出有效应用策略,从而全面阐述基础测绘技术重要性。
无人机倾斜摄影测量三维建模及应用分析
Authors: 吴 江明 , 傅 冬华
Published: March 2020

三维城市使用描绘城市地表景观的三维立体模型来展示城市的空间构型信息,可以说是城市信息不可或缺的载体。对于城市的规划、创建、维护以及应急来说含有非常重要的用途,三维城市已经全面地呈现出它在经济和实用方面的有利价值。倾斜摄影技术合理的将定位、图像、摄影等多方面的技术融合在一起,在速度极快的物体上捆绑摄影、定位设备,可以更加全面、快速、精准地采集相关地理信息。所以无人机倾斜摄影技术已经被广泛应用于各个领域。
关于顶管工程对地面沉降影响的研究
Authors: 许 望贤
Published: March 2020

顶管施工是一种新型的地下土层施工方式,与盾构施工相比,顶管施工不需要开挖面层即可以实现在地下进行布线,其具有工序简单、成本低、施工时间短等优势。但顶管施工对土层结构的改变会使地面发生沉降,因此本文以梧州市苍梧县旧城区雨污截流渠三期工程中应用的顶管施工为例,对施工中地面沉降的影响进行了研究。
重金属污染土壤修复技术及工程应用
Authors: 黄 昕
Published: March 2020

现如今,我国的土壤重金属污染事件发生频率明显提高,其直接影响着人们的身体健康和农业生产的稳定性。对此,社会也更加关注环境保护。土壤金属污染的修复与处理在环境保护中尤为关键。本文就将分析重金属污染土壤修复技术及工程应用,以改善土壤环境。
物化探测点布设中测绘技术方法应用分析
Authors: 赵 惠德
Published: March 2020

不同的地质工作对物化探工作的要求不同,不同的工作环境、不同的精度指标也对物化探测点的布设技术方法提出了不同的要求。本文从工作的要求、地形的条件、设备的特点、布设的方法、最终达到的精度结果等多个方面进行了阐述,并提出了一些建议,对物化探测点布设的方案拟定和施测具有一定的参考意义。
现代测绘技术在国土测绘中的应用分析
Authors: 亓 晓敏 , 谢 国帅
Published: March 2020

国土测绘是一项比较传统的工作,测绘方法从古代人工丈量变为以前的人工野外测绘,再到现代运用高科技技术,实现质的飞跃。现代信息技术的出现促使国土测绘环节工作效率更高,因此,有必要研究此技术的应用途径。
测绘地理信息在应急测绘中的应用实践
Authors: 韩 棚举
Published: March 2020

在应急测绘项目中运用测绘地理信息有着非常重要的意义。在具体运用过程中,利用现代化技术开展信息测绘,可以辅助有关部门实施决策,从而有效的管理和控制了突发事件。因此,要重视对这方面的研究,通过全面分析应急测绘处理技术,可以合理解决应急事件。基于此,本文主要探讨了测绘地理信息在应急测绘中的应用。
岩土工程施工中深基坑支护问题探究
Authors: 芦 边
Published: March 2020

现阶段,城市化建设不断增加,使得人们高度关注地下空间的利用以及开发,带动着深基坑工程的发展。在岩土工程施工中,深基坑支护是一项常见的施工技术,并且随着科技的发展,深基坑支护也有了一定的发展。本文通过对深基坑支护问题进行分析,希望提出更好的措施来解决岩土工程中存在的问题,推动我国建筑业的不断发展。
APLIKASI PENGELOLAAN DATA KEPEGAWAIAN BERBASIS WEB PADA PT. PELAYARAN SAKTI INTI MAKMUR PALEMBANG
Authors: Wijaya Novan , Febriyanti Adelia Rizky , Wibowo Anton
Published: March 2020

PT. Pelayaran Sakti Inti Makmur is a express bahari fast boat operator company that has served people of Indonesia since 1990 until today in iall Indonesia waters. PT. Pelayaran Sakti Inti Makmur still uses a manual system such as recap data everyday, week and month. Manually, system often have errors in the recap process, both have the same data and even missing data. The application to be built aims to make it easier to manage staffing data at PT. Pelayaran Sakti Inti Makmur so that it becomes more effective and efficient. Staffing data includes calculating employee work period automatically, assisting in taking care of permits, leave, resignation, warning letters, and simplifying HRD in the process of making reports. Data collection techniques used were interviews, observation and literature study. System development methodology used is iterative method, which in iterative method includes the stages of analysis, design, program code creation and testing to describe proposed application using rich picture, DFD, Context Diagram, and ERD. This application is created using the PHP programming language and database management using MySQL.
COOPERATION IN LOGISTICS TECHNOLOGY RESEARCH: HOW TWINNING PROJECT AFFECTS R+D IN THE FIELD OF LOGISTIC SYSTEMS AND NETWORKS
Authors: Bányai Tamás , Illés Béla , Landschützer Christian , Schenk Fabian , Massi Flavien
Published: March 2020

The overall aim of the UMi-TWINN project was to reinforce the scientific excellence and innovation capacity in logistic systems of the University of Miskolc and its high-quality twinning partners for the benefit of different industries and logistics markets. To boost twinning partners' scientific excellence and innovation capacity in logistics technologies, as well as implementing a research and innovation strategy we have focused on the following three sub-topics: design of logistic systems and networks, intelligent transport systems and dynamical analysis of materials handling machines. Within the frame of this paper the authors describe the main results in the field of design of logistic systems.
INTRODUCTION OF DEMO3D INTO THE SCIENTIFIC EDUCATION OF MATERIAL HANDLING
Authors: Telek Péter , Trummer Wolfgang
Published: March 2020

Using of advanced machines and methods requires highly educated engineers, who gain their basic knowledge at universities. In the aspect of material handling, the Institute of Logistics of the University of Miskolc (LOG) is one of the leading education centres in Hungary, so its teaching materials, methods and devices have significant effects to the knowledge of future logistic engineers. In this paper, we describe the state of the art of planning of material handling and the education structure of LOG. Main objective of this paper is to present developing possibilities of the scientific education of LOG with some help of the Institute of Engineering Logistics of TU Graz (ITL) in the frame of project UMi-TWINN. One of the most important results of the project is the application of the Demo3D software for the education of material handling. The developed examples, videos, sheets and other documentations are directly usable in the teaching curricula of different courses of LOG.
DEVELOPMENT OF A STEERING AND BRAKING SYSTEM FOR AUTOMATED CARGO-BIKES
Authors: Junge Lars , Schmidt Michael , Zug Sebastian , Schmidt Stephan
Published: March 2020

To relieve busy urban areas of automobile traffic and exhaust emissions, bike sharing systems are increasingly being implemented. In order to expand the limited transport capacity of a bicycle, cargo bikes are used for private transport in the narrow urban area. The problem is often the availability of a cargo bike at a determined time. The limited number and possibly inhomogeneous distribution in the urban area reduces availability of the cargo bikes. To increase the acceptance of the system, the goal must therefore be to significantly increase the availability at all locations in the urban area. So far, the consumer had to get to the means of transport, now the cargo bike should autonomously navigate to the user and maneuver. This article focuses on the actuators and their modeling as an elementary part of the overall system to enable the automated journey of a cargo bike. There are currently no off-the-shelf components available for braking and steering. The steering and braking system must be able to be controlled separately from each other by humans or automatically, in order to allow manual and automatic operation. For brake and steering a suitable concept is developed, a simulation model is built and evaluated. In addition, the steering mechanism is evaluated with measured values on the real test vehicle.
浅谈现浇钢筋混凝土板墙加固在老旧房屋修缮中的应用
Authors: 陆 祥建
Published: March 2020

随着城市化建设进程的不断发展，城市中具有的很多老旧建筑，想要和城市的整体形象相协调，就必须进行拆除与加固修缮这两种方式。而针对老旧街区房屋想要继续保持之前的风格与风貌，满足修旧如旧的效果，就必须使用现浇钢筋混凝土板墙加固技术，此种施工方法的加固效果非常好，而且造价成本也不高。对此，此文通过详细的案例与加固方法，详细分析了板墙加固施工要点，希望能够给未来的相关研究提供参考。
公路水运工程试验检测的可持续发展
Authors: 宋 林峰
Published: March 2020

随着当前我国社会的不断发展，公路水运工程项目往往面临着较高的要求，不仅仅规模比较大，具体施工建设的质量要求同样也越来越突出，如此也就必然需要进一步优化公路水运工程建设效果，借助于多种手段提升施工水平。试验检测工作作为公路水运工程建设中比较重要的一个辅助手段，确实表现出了较强的作用价值，应该引起建设管理人员的高度重视，进一步提升试验检测工作的应用效果。
高层建筑的人防工程结构设计研究
Authors: 周 慧芳 , 王 哲
Published: March 2020

文章首先介绍了人防工程结构的设计概念及原理；其后，从人员疏散、战时应用、功能分区、平战结合四个角度出发，分析了高层建筑的人防工程结构设计需求；最后，围绕结构及区位关系、结构基础设计、结构构造设计、结构顶板设计四个方面，提出了高层建筑的人防工程结构设计要点。
数字化测图在大比例尺地形图测绘中的应用
Authors: 程 琳琳
Published: March 2020

在最近的几年时间里，我国社会科学技术整体水平得到了显著的进步，有效的促进了各类信息化车辆仪器的适用范围的扩大，并且推动了计算机辅助制图技术的稳定发展，使得地形测量工作朝着自动化、数字化的方向逐渐发展。地形测量由数字测图过渡为数字化测图，测量所得到的信息不仅能够运用在地形图的绘制之中，并且最为关键的是以电子设备为载体，构建可大范围使用的数字地形图。数字化测图是当前最为前沿的一种测图模式，与模拟测图相比较来说，具有更好的优越性。
公路桥梁施工中预应力的应用及存在的问题
Authors: 时 冬冬
Published: March 2020

在我国社会经济快速发展的推动下，有效的带动了整个道路桥梁工程建设工作的发展，从而促进了预应力技术水平的不断提高，并逐渐的成为了当下道路桥梁工程施工工作开展中的一项重要基础技术。将预应力技术切实的引用到公路桥梁施工工作之中，不但可以促进道路桥梁工程施工质量的提升，并且能够针对到了桥梁工作施工工作进行全面的监控，从而为施工方案的完善给予帮助，促进道路桥梁工程整体施工质量的不断提升。
大型公用建筑设计项目风险因素研究
Authors: 吴 崇岩
Published: March 2020

随着我国建筑事业不断发展，对大型公用建筑设计项目的要求也随之增多，对大型公用建筑设计项目风险因素开展分析，推动建筑行业良好发展。文章对大型公用建筑设计项目风险因素进行研究，分析其常规风险因素和特殊风险因素，并总结出培养管理人才、提高管理意识、完善管理制度和加强防控措施四项风险管理策略，希望能为广大建筑设计工作者提供有效帮助。
BIM技术在建筑工程结构设计中的应用研究
Authors: 刘 柯廷
Published: March 2020

技术的应用来破解建筑业所面临的一系列的困境。BIM技术是一种针对建筑工程全过程的信息模型管理技术。它的应用不仅能带来技术的变化，同时也给管理的改变与提高提供了新的方法。
建筑给排水施工技术的优化及发展探讨
Authors: 赵 世伟 , 李 志强
Published: March 2020

建筑工程施工中给排水的施工质量直接关系到建筑项目整体的竣工质量，文章结合笔者个人工作经验，探讨了建筑给排水施工当前存在的若干问题，并给出了优化及发展建议，为今后更好的提升建筑给排水施工质量提供参考与借鉴。
薄型低温不锈钢罐底板焊接变形的控制
Authors: 汪 涛
Published: March 2020

在进行薄型低温不锈钢罐底板的焊接中，由于底板厚度较低，极容易产生变形，需要重点控制。基于此，文章结合LNG常压低温双层罐的底板焊接项目，分析了不锈钢罐底板焊接变形的常见种类及其成因，并提出了选定适宜的焊接方法及工艺参数、控制焊接顺序、降低焊接热量等一系列焊接变形的控制措施。
论建筑工程施工工序的质量控制
Authors: 张 华 , 张 元同 , 李 登会 , 张 成
Published: March 2020

对建筑工程施工予以分析可知，每道工序间存在紧密的关联性，而且呈现出相互制约的关系，若想使得工程质量达到要求，必须要保证工序质量能够得到有效管控。在对施工质量进行控制时，必须要重视工序活动效果、活动条件，确保质量控制赋有实效，如此方可使得施工阶段工序质量有大幅提升。在现阶段，经济发展的速度是较快的，在此背景下，建筑市场的竞争变得更为激烈，企业若想在市场中保持优势，就一定要对施工工序进行良好的控制，确保质量控制目标能够切实达成。
既有建筑外墙保温装饰一体化板工程技术改造的研究应用
Authors: 苏 养龙
Published: March 2020

近年来，社会各界建筑节能与绿色环保理念不断深入，人们对外墙保温防火性能提出了更高的需求，外墙保温装饰一体化板凭借自身优越性从各类板材中脱颖而出。但由于施工技术、材料和管理等方面存在的不确定因素使得在建设过程中和后期的使用过程中存在一些问题，既有建筑来说其节能效果达不到现阶段社会的具体要求，因此，既有建筑的外墙保温装饰一体化板就需要进行工程改造。文章通过分析一体化板在施工时面临的质量问题，通过加强质量诊断、明确改造要点、合理选用施工材料、优化一体化板结构等方式实现对建筑外墙的技术改造，为建筑功能的稳定性和使用安全提供了重大保障。
电力工程输电线路施工技术及质量控制探究
Authors: 孔 维权 , 王 宇
Published: March 2020

电力企业只有不断提升自身的技术水平才能够带动自身的长远发展，因此一定要注重自身的施工技术，这样才能够稳定自身的发展，电力施工技术水平的好坏及服务水平与人们的日常生活息息相关，加强服务水平能够指引企业长远的发展方向，这也是行业需要思考的关键性问题。
煤矿冲击地压发生机理及治理方案研究
Authors: 赵 凯凯 , 乔 冲冲 , 王 守林
Published: March 2020

在煤炭的开采过程中，可能会遇到的主要动力灾难就是冲击地压。近年来，由于人们对于地下煤炭的开采量越来越大，煤层开采逐渐朝着更深的地层发展，而造成了煤炭开采的过程中冲击地压的问题越来越严重。在开采施工的区域，特别是前方区域的煤层，因为受到了开采的应力变化，原有的煤层平衡瞬间被打破，产生强大的冲击力，这是一种相当复杂的煤矿开采岩层的动力学现象。当煤层的冲击出现的时候，不会引起其他更为严重的井下生产的灾害，常见的就是瓦斯巨量释放，矿井冒水等等，这对于井下作业是非常具备危险性的，对于井下工人的生命安全也有巨大的威胁，更严重的还会造成一系列安全生产事故，对煤矿企业的发展造成严重影响。
Intensity Ratio of LH2 Complexes from Rhodopseudomonas palustris and Rhodobacter sphaeroides for Purity Determination
Authors: Prihastyanti Monika NU , Kurniawan Jovine M , Yusuf Melisa M , Azmi Sherly S , Ilmi Mustafavi C , Indarto Michelle L , Hoetomo Stefan C , Wijaya Melina E , Jatiyati Greta , Brotosudarmo Tatas H.P. , Heriyanto Heriyanto
Published: March 2020

Purification procedures to obtain light-harvesting complexes were performed on two photosynthetic bacteria, i.e. Rhodospseudomonas (Rps.) palustris and Rhodobacter (Rb.) sphaeroides. In this study, purification was initially carried out using series of centrifugation towards the bacteria cell to acquire chromatophore of the bacteria. Application of detergent (lauryldimethylamine oxide, or LDAO) to the chromatophore enabled the extraction of membrane containing photosynthetic apparatus. Further purification involved the application of sucrose density gradient centrifugation and ion exchange chromatography. The purity of collected LH2 complexes can be determined by calculating the ratio of AB850 : Aprotein. The resulting LH2 complexes from both bacteria showed relatively high ratio suggesting the purity of the complexes.
Thermal Degradation Kinetics of Encapsulated Palm Carotenes Using Different Combination of Wall Materials
Authors: Hong Khoo Mun , Indrawati Renny , Brotosudarmo Tatas HP , Limantara Leenawaty
Published: March 2020

Palm oil is known as one of the richest sources of carotenes. Carotenes concentrate could be prepared from crude palm oil and possessing potency to be used as nutraceutical materials. Due to the susceptibility of carotenes against heat, the encapsulation procedure might be applied to provide protections. The present study was aimed to learn the influence of using different combination of wall materials toward the thermal degradation kinetics of palm carotenes. Maltodextrin was used as primary wall material, being combined with various surface-active agents, i.e. Tween-80 (A), Tween-20 (B), and Arabic gum (C). The carotenes concentrate was encapsulated through emulsification steps, and the vivid yellow powder was obtained after freeze drying process. Then, encapsulated palm carotenes were stored in 200C, 350C, and 500C for several days, and the color, carotenes spectrum, as well as water content were monitored periodically. The kinetics of thermal degradation of carotenes were estimated using Arrhenius equation. The results showed that the use of different combination of wall materials exhibited distinct degradation rate. The combination of maltodextrin and Tween-80 gave preferable protection compared to the others, being half-degraded after 51 days in 200C.
THE IMPLEMENTATION OF ENTRA (ENGLISH FOR TRANSPORTATION) IN ESP PROGRAM OF PPI MADIUN
Authors: Widiyanah Ima , Amaliyasari Maya Rizki
Published: March 2020

The aim of this research is to describe the students' responses on the implementation of EnTra in ESP Program of PPI Madiun. The design of this study is descriptive qualitative in which data sources obtained from the students' responses on the interviews and questionnaires after experiencing of using the EnTra Application in English class. The result shows that, from over 60 students as respondents, agree that the application is useful for them in studying English in the area of transportation. There are seven indicators used to measure the student' perception toward the application, those are: aspects of the material relevance, aspects of material organizing, aspects of evaluation / practice questions, aspects of language, aspects of the effects for learning strategies, aspects of software engineering, and aspects of visual appearance. The average students' scoring upon the application after using it for three months is 4,03 based on range scoring 1-5. From this result, it can be concluded that EnTra application is qualified enough to use as the supplementary media in learning English transportation.
GRAMMATICAL ERRORS ANALYSIS ON EFL LEARNERS’ WRITING
Authors: Huda Tanzil , Wuda Rica Wakhyu
Published: March 2020

Writing is supposed to be a complicated language skill. There exists a lot of sub-skills should be learnt by EFL/ESL learners in order to write well such as vocabulary acquisition and grammatical mastery.  In the process of writing, the learners should put  ideas into  phrases, clauses, and sentences by keeping the well-formedness of the structure. In addition, the learners should  also be aware of  unity, coherent, cohesiveness of the sentences when they are  constructed into paragraph/s and larger form of composition i.e., text or essay. Due to the complexity of writing skill, the learners potentially make error/s. The recent study  was intended to investigate the dominant error/s  made by the learners. This study also tried to explore the factors cause those learners made the error/s. This study revealed that the dominant error made by the students was misformation errors which were occured because of the interference of the learners’ mother tongue i.e., the learners  still got confused to change the verb into past participle, as what it was called as intralanguage error in which  it was taken palce because inadequate knowledge how to  use or to change verb. In addition, it was occured by some other  factors such as environment, the process of teaching and learning including of learning style and feedback, the availability of learning source, and low motivation.
AN ANALYSIS TEACHER’S MISTAKES IN TEACHING ENGLISH AT KINDERGARTEN AR-ROIHAN LAWANG
Authors: Rahmah Tities Hijratur , Fandyasari Melisa Wahyu
Published: March 2020

In Indonesia, English is taught even in the most basic educational institutions, that is Kindergarten. But, most of the Kindergarten teacher did not graduate from English department, so the English they taught often contain the mistakes. This study aimed to identify the mistakes that was made by the teacher during teaching and learning English. The designed of this study is descriptive-qualitative research. The data of this study was collected from the sentences containing mistakes spoken by the teacher in teaching and learning activity at Kindergarten Ar-Roihan Lawang. The result of this study showed that the teacher did some mistakes when she taught English in the class. The researcher found 32 mistakes made by the teacher. The most mistakes made by the teacher is structure of the sentences with 18 mistakes, the second is the plural of nouns with 8 mistakes, and the last is tenses with 6 mistakes.
Pharmacological Stimulation of Wnt/ß-catenin Signaling Pathway Attenuates the Course of Thioacetamide-Induced Acute Liver Failure
Authors: KOBLIHOVÁ E. , MRÁZOVÁ I. , VAŇOURKOVÁ Z. , MAXOVÁ H. , KIKERLOVÁ S. , HUSKOVÁ Z. , RYSKA M. , FRONĚK J. , VERNEROVÁ Z.
Published: March 2020

Acute liver failure (ALF) is known for extremely high mortality rate, the result of widespread damage of hepatocytes. Orthotopic liver transplantation is the only effective therapy but its application is limited by the scarcity of donor organs. Given the importance in the liver biology of Wnt/β-catenin signaling pathway, we hypothesized that its stimulation could enhance hepatocyte regeneration and attenuate the course of thioacetamide (TAA)-induced ALF in Lewis rats. Chronic treatment with Wnt agonist was started either immediately after hepatotoxic insult (“early treatment”) or when signs of ALF had developed (“late treatment”). Only 23 % of untreated Lewis rats survived till the end of experiment. They showed marked increases in plasma alanine aminotransferase (ALT) activity and bilirubin and ammonia (NH3) levels; plasma albumin decreased significantly. “Early” and “late” Wnt agonist treatment raised the final survival rate to 69 % and 63 %, respectively, and normalized ALT, NH3, bilirubin and albumin levels. In conclusion, the results show that treatment with Wnt agonist attenuates the course of TAA-induced ALF in Lewis rats, both with treatment initiated immediately after hepatotoxic insult and in the phase when ALF has already developed. Thus, the pharmacological stimulation of Wnt/β-catenin signaling pathway can present a new approach to ALF treatment.
Ameliorative Effect of Sesamin in Cisplatin-Induced Nephrotoxicity in Rats by Suppressing Inflammation, Oxidative/Nitrosative Stress, and Cellular Damage
Authors: ALI B. , AL SALAM S. , AL SULEIMANI Y. , AL ZA'ABI M. , ASHIQUE M. , MANOJ P. , SUDHADEVI M. , AL TOBI M. , NEMMAR A.
Published: March 2020

Nephrotoxicity of cisplatin (CP) involves renal oxidative stress and inflammation, and sesamin (a major liganin in many plants) has strong antioxidant and antiinflammatory actions. Therefore, we investigated here the possible mitigative action of sesamin on CP nephrotoxicity in rats. Sesamin was given orally (5 mg/kg/day, 10 days), and on the 7th day, some of the treated rats were injected intraperitoneally with either saline or CP (5 mg/kg). On the 11th day, rats were sacrificed, and blood and urine samples and kidneys were collected for biochemical estimation of several traditional and novel indices of renal damage in plasma and urine, several oxidative and nitrosative indices in kidneys, and assessment of histopathological renal damage. CP significantly and adversely altered all the physiological, biochemical and histopathological indices of renal function measured. Kidneys of CP‐treated rats had a moderate degree of necrosis. This was markedly lessened when CP was given simultaneously with sesamin. Sesamin treatment did not significantly alter the renal CP concentration. The results suggested that sesamin had ameliorated CP nephrotoxicity in rats by reversing the CP-induced oxidative stress and inflammation. Pending further pharmacological and toxicological studies sesamin may be considered a potentially useful nephroprotective agent.
Metabolic Cooperation in the Ovarian Follicle
Authors: FONTANA J. , MARTÍNKOVÁ S. , PETR J. , ŽALMANOVÁ T. , TRNKA J.
Published: March 2020

Granulosa cells (GCs) are somatic cells essential for establishing and maintaining bi-directional communication with the oocytes. This connection has a profound importance for the delivery of energy substrates, structural components and ions to the maturing oocyte through gap junctions. Cumulus cells, group of closely associated GCs, surround the oocyte and can diminished the effect of harmful environmental insults. Both GCs and oocytes prefer different energy substrates in their cellular metabolism: GCs are more glycolytic, whereas oocytes rely more on oxidative phosphorylation pathway. The interconnection of these cells is emphasized by the fact that GCs supply oocytes with intermediates produced in glycolysis. The number of GCs surrounding the oocyte and their age affect the energy status of oocytes. This review summarises available studies collaboration of cellular types in the ovarian follicle from the point of view of energy metabolism, signaling and protection of toxic insults. A deeper knowledge of the underlying mechanisms is crucial for better methods to prevent and treat infertility and to improve the technology of in vitro fertilization.
Effects of Histidine Supplementation on Amino Acid Metabolism in Rats
Authors: HOLEČEK M. , VODENIČAROVOVÁ M.
Published: March 2020

Histidine (HIS) is investigated for therapy of various disorders and as a nutritional supplement to enhance muscle performance. We examined effects of HIS on amino acid and protein metabolism. Rats consumed HIS in a drinking water at a dose of 0.5 g/l (low HIS), 2 g/l (high HIS) or 0 g/l (control) for 4 weeks. At the end of the study, the animals were euthanized and blood plasma, liver, soleus (SOL), tibialis (TIB), and extensor digitorum longus (EDL) muscles analysed. HIS supplementation increased food intake, body weight and mass and protein contents of the liver and kidneys, but not muscles. In blood plasma there were increases in glucose, urea, and several amino acids, particularly alanine, proline, aspartate, and glutamate and in high HIS group, ammonia was increased. The main findings in the liver were decreased concentrations of methionine, aspartate, and glycine and increased alanine. In muscles of HIS-consuming animals increased alanine and glutamine. In high HIS group (in SOL and TIB) increased chymotrypsin-like activity of proteasome (indicates increased proteolysis); in SOL decreased anserine (beta-alanyl-N1-methylhistidine). We conclude that HIS supple-mentation increases ammonia production, alanine and glutamine synthesis in muscles, affects turnover of proteins and HIS-containing peptides, and increases requirements for glycine and methionine.
Proses Ritus Kematian pada Masyarakat Etnik Muna di Kota Kendari
Authors: Sutriani Iko , Marafad La Ode Sidu , Aso La
Published: March 2020

Tujuan penelitian ini adalah untuk mendeskripsikan proses ritus kematian pada masyarakat etnik Muna. Penelitian ini bersifat kualitatif, dimana Peneliti menggambarkan secara detail proses ritus kematian pada masyarakat etnik Muna. Teknik pengumpulan data dilakukan melalui pengamatan, wawancara mendalam dan studi dokumen. Hasil penelitian ini menunjukkan bahwa proses ritus kematian pada masyarakat etnik Muna terdiri atas tujuh ritus yaitu (1) ritus kaalingkita (memandikan maya secara biasa), (2) ritus kaselino wite (penggalian tanah kuburan), (3) ritus kakadiu wadhibu (memandikan mayat secara wajib), (4) ritus kabasano haroa turuntana (pembacaan doa untuk bekal mayat), (5) ritus kakoburu (penguburan), (6) ritus kansolo-nsolo (kunjungan ke kuburan), dan (7) ritus poalo (memperingati malam-malam tertentu sesudah penguburan).
rol del pedagogo infantil en procesos de inclusión
Authors: Gutiérrez Beltrán Yeraldine , Patarrayo Sánchez Laura , Rincón Infante Sandra Milena , Blanco Vega María de Jesús
Published: March 2020

Este texto deviene de la investigación realizada en el segundo semestre del año 2018 y el primero de 2019, titulada “Orientaciones pedagógicas para el fortalecimiento de la expresión emocional en población infantil con Trastorno del Espectro Autista - TEA - del Gimnasio Campestre de Guilford”, institución de educación inclusiva que tiene como misión ofrecer una formación integral propiciando un ambiente académico emocional y social, desde el desarrollo cognitivo, físico y socio afectivo, respetando ritmos de aprendizaje, la formación en valores, el reconocimiento a las diferencias individuales y el desarrollo de la autonomía; escenario educativo que propone un diseño curricular flexible y que permite formación a partir de las condiciones particulares de los estudiantes. El objetivo del estudio fue diseñar orientaciones pedagógicas que fortalezcan las habilidades de expresión emocional de la población infantil de la institución educativa participante y a su vez favorecer los procesos de inclusión. Las orientaciones pedagógicas son entendidas para esta investigación como pautas que apoyan la praxis del docente en el aula, desde el perfil del Pedagogo Infantil y buscan ser una guía para fortalecer la expresión emocional en los niños, aspecto concebido como eje fundamental de la dimensión social y afectiva del ser humano, que asegura el desarrollo integral de la infancia. En términos metodológicos este estudio es básico de corte cualitativo y trabaja el método estudio de caso, con técnicas e instrumentos como la observación participante a través de un registro, entrevista semiestructurada a docentes con guion de entrevista y matrices de sistematización y análisis. Los resultados están enmarcados en la caracterización de habilidades de expresión emocional de la población infantil con TEA, en procesos de inclusión, de la institución educativa participante, así como las apreciaciones de los docentes para identificar los rasgos distintivos en cuanto a la expresión de emociones en la muestra poblacional, permitiendo la construcción de pautas pedagógicas como propuesta de reflexión y observación soporte, para la aplicación – a partir de las orientaciones - desde la mirada del docente en el aula, que aporte a potenciar la expresión emocional de los niños desde el perfil del profesor.
Rol de la fisioterapia en los cuidados paliativos
Authors: Pereira Rodriguez Javier Eliecer
Published: March 2020

Introducción: Los cuidados paliativos son un enfoque realizado por un equipo multidisciplinario para mejorar la calidad de vida de los pacientes con enfermedad terminal y sus familias. Por otro lado, la fisioterapia favorece a la disminución deposibles discapacidades causadas por la enfermedad o sus tratamientos.

Objetivo: Determinar el rol de la fisioterapia en los cuidados paliativos.

Materiales y métodos:Revisión sistemática con análisis descriptivo y cronología retrospectiva. Se recaudó información sobre la población, grupos de intervención y control, tipología de la patología, intervención, período y frecuencia de intervención y resultados. Los estudios se identificaron y seleccionaron mediante las recomendaciones de la Declaración de PRISMA y la Colaboración Cochrane, además, se evaluó la calidad metodológica de los estudios incluidos en la revisión a través de la Escala de PEDro.

Resultados: El equipo de fisioterapia se centra principalmente en un programa de ejercicios en el que no existe dosificación sobre el tipo, frecuencia, intensidad y la duración de los ejercicios que se deben administrar a los pacientes, ni tampoco en qué etapa de la enfermedad se debe administrar y de qué manera, la dosificación será individual y dependiendo en la etapa de la enfermedad.

Conclusión: El papel principal del fisioterapeuta es el mantenimiento de la vida activa hasta la muerte, incentivar al paciente la actividad corporal y disminuir los síntomas causados por la enfermedad.
Revisión sobre la efectividad de la terapia en espejo en el proceso de rehabilitación de miembros superiores en pacientes con accidente cerebrovascular
Authors: Cepeda-Vega Linda Carolina , Gómez-Blanco María Alexandra
Published: March 2020

Introducción: La afección en extremidades superiores posterior a un accidente cerebrovascular se considera la más frecuente y esta deja secuelas a corto, mediano y largo plazo que intervienen en el desarrollo de actividades básicas cotidianas o de la vida diaria en el usuario como bañarse, vestirse, peinarse, entre otras.  la terapia en espejo pretende ayudar a que esta rehabilitación sea más fácil creando una ilusión visual del miembro afectado como si estuviese sano, Objetivo: verificar Mediante la revisión de bibliografía la efectividad de la terapia en espejo en el proceso de rehabilitación de miembros superiores en pacientes con accidente cerebrovascular. Método: se hizo una revisión de literatura de 47 artículos relacionados con la terapia en espejo y el proceso de rehabilitación en miembros superiores, teniendo en cuenta publicaciones en inglés y español en las bases de datos Pubmed, Elsevier, Science Direct, Dialnet, Medline basándonos en los últimos 10 años. Resultados: Los estudios mostraron que la terapia en espejo es efectiva en el proceso de rehabilitación motora en miembros superiores en pacientes con accidente cerebrovascular siempre y cuando se combine con terapias complementarias y su periodo de rehabilitación sea extenso Conclusión: La terapia en espejo es considerada efectiva por la intervención de las neuronas espejo en el proceso de aprendizaje la cual en compañía de otros medios ayuda a la pronta recuperación de la movilidad del paciente con accidente cerebrovascular, mejorando así el desarrollo de sus actividades básicas cotidianas contribuyendo a una mejora en su calidad de vida.
Efecto del ejercicio físico sobre la concentración de adipocinas en adultos con obesidad. Una revisión sistemática
Authors: Vázquez-Rodríguez Anabel , Candia-Luján Ramón , Enríquez-Del Castillo Liliana Aracely , Reza-López Sandra A. , Carrasco-Legleu Claudia E.
Published: March 2020

Objetivo: realizar una revisión sistemática de la evidencia publicada para determinar el efecto de diferentes tipos de ejercicio en la concentración de adipocinas en adultos con obesidad. Método: Se realizó una búsqueda en las bases de datos PubMed, EBSCO (Medline, MedicLatina) y el buscador Google Académico. Los descriptores utilizados fueron los siguientes: en inglés, “adipocytokines” OR “adipokines”, “exercise” OR “physical activity” OR “training”, “adults” AND “obese”; en español, “adipocinas”, “ejercicio” o “actividad física”, “adultos” y “obesidad”. Resultados: Se incluyeron 13 estudios de diferentes modalidades de ejercicio como aerobio, anaerobio y mixto. Se reporta un aumento en las concentraciones de adiponectina, así como una disminución en los niveles de leptina y (factor de necrosis tumoral alfa) TNFα.  Conclusión: Se observó que existe un mayor beneficio con el ejercicio aerobio marcando mejoras en los niveles de adipocinas.
Propeller Selection by Means of Pareto-Optimal Sets Applied to Flight Performance
Authors: Slavik Svatomir , Klesa Jan , Brabec Jiri
Published: March 2020

Selection process of the propeller for short take-off and landing (STOL) category aircraft is described. The aim is to achieve the highest possible performance with fixed propeller, i.e., high maximal horizontal and cruise speed, short take-off and high rate of climb. These requirements are contradictory and so Pareto sets were used in order to find the optimal propeller. The method is applied to a family of geometrically similar propellers that are suitable for 73.5 kW (100 hp) piston engine designed for ultralight category aircraft with maximal take-off weight of 472.5 kg. The propellers have from two to eight blades, blade angle settings from 15° to 40° and diameter from 1.1 m to 2.65 m. Pareto frontier is designed for each pair of flight conditions, and the optimal propeller is selected according to these results. For comparison, the optimal propeller selection from the propeller family by means of a standard single-optimal process based on the speed power coefficient cs is also used. Use of Pareto sets leads to considerable performance increase for the set of contradictory requirements. Therefore, high performance for a low price for the given aircraft can be achieved. The described method can be used for propeller optimization in similar cases.
Root Contact between Maize and Alfalfa Facilitates Nitrogen Transfer and Uptake Using Techniques of Foliar 15N-Labeling
Authors: Shao Zeqiang , Wang Xinyu , Gao Qiang , Zhang Hualiang , Yu Hailing , Wang Yin , Zhang Jinjing , Nasar Jamal , Gao Yingzhi
Published: March 2020

Belowground nitrogen (N) transfer from legumes to non-legumes provides an important N source for crop yield and N utilization. However, whether root contact facilitates N transfer and the extent to which N transfer contributes to crop productivity and N utilization have not been clarified. In our study, two-year rain shelter experiments were conducted to quantify the effect of root contact on N transfer in a maize/alfalfa intercropping system. N transfer occurred mainly one direction from alfalfa to maize during the growth period. Following the N0 treatment, the amount of N transfer from alfalfa to maize was 204.56 mg pot−1 with no root barrier and 165.13 mg pot−1 with a nylon net barrier, accounting for 4.72% and 4.48% of the total N accumulated in maize, respectively. Following the N1 treatment, the amount of N transfer from alfalfa to maize was 197.70 mg pot−1 with no root barrier and 139.04 mg pot−1 with a nylon net barrier, accounting for 3.64% and 2.36% of the total N accumulated in the maize, respectively. Furthermore, the amount of N transfer without no root barrier was 1.24–1.42 times higher than that with a nylon net barrier regardless of the level of N addition. Our results highlight the importance and the relevance of root contact for the enhancement of N transfer in a maize/alfalfa intercropping system.
Use of Fresh Scotta Whey as an Additive for Alfalfa Silage
Authors: Mariotti Marco , Fratini Filippo , Cerri Domenico , Andreuccetti Victoria , Giglio Roberta , Angeletti Francesco G. S. , Turchi Barbara
Published: March 2020

Scotta is a dairy industry waste obtained by ricotta cheese production. Because of its high availability and its high lactose content, scotta could be used as an additive to improve fermentation characteristics of alfalfa silage. Silage samples were obtained for 2 years from an alfalfa second cut, collecting the forage at three growth stages: mid bud (MB), early flowering (EF), and late flowering (LF). After wilting the forage at 38% dry matter (DM), four scotta doses were added (0, 75, 150, and 300 g/kg fresh forage) and the main chemical and microbiological characteristics were evaluated after 3, 13, and 90 days of ensiling (DOE). The lowest pH (4.3) was recorded in the EF and LF growth stages, after 90 DOE and with the highest scotta dose (300 g/kg fresh forage). After 90 DOE, the concentration of the main spoilage microorganisms and clostridial spore loads was always negligible. The addition of scotta decreased pH and fiber fractions, increased the relative feed value, and had no effect on the crude protein concentration or the total digestible nutrients. Therefore, the scotta can be successfully used as an additive to improve the fermentation characteristics of alfalfa silage.
Effects of Extruded Linseed and Soybean Dietary Supplementation on Lactation Performance, First-Service Conception Rate, and Mastitis Incidence in Holstein Dairy Cows
Authors: Dawod Ahmed , Ahmed Hamada , Abou-Elkhair Reham , Elbaz Hamed T. , Taha Ayman E. , Swelum Ayman A. , Alhidary Ibrahim A. , Saadeldin Islam M. , Al-Ghadi Muath Q. , Ba-Awadh Hani A. , Hussein Elsayed O. S. , Al-Sagheer Adham A.
Published: March 2020

This study quantifies the effects of extruded linseed and soybean (ELS) dietary supplementation on milk yield, composition, and fatty acid profiles, as well as first-service conception rate in Holstein dairy cows. Seventy-eight open Holstein dairy cows were divided into two groups: (1) a control, which received a basal diet; and (2) a test group, which received a basal diet supplemented with the ELS (650 g/kg of extruded linseed and 150 g/kg of extruded soybean) at a rate of 100 g/kg. In the ELS group, milk yield per day and solid not fat (SNF) yield increased by 3.26% and 0.88%, respectively, in relation to the control. Percentage milk fat decreased significantly by 1.4% in the ELS group when compared with the control. The ELS supplement resulted in a decrease in saturated fatty acids (SFAs) and an increase in monounsaturated (MUFAs) and polyunsaturated fatty acids (PUFAs) in milk. In conclusion, the supplementation of dairy cow feed with 100 g/kg of ELS increases milk yield and milk unsaturated fatty acids (especially MUFAs and PUFAs). ELS supplementation also causes a decrease in percentage fat and SFA levels but does not affect the first-service conception rate or the incidence rate of mastitis.
An Improved Algorithm for Detecting Pneumonia Based on YOLOv3
Authors: Yao Shangjie , Chen Yaowu , Tian Xiang , Jiang Rongxin , Ma Shuhao
Published: March 2020

Pneumonia is a disease that develops rapidly and seriously threatens the survival and health of human beings. At present, the computer-aided diagnosis (CAD) of pneumonia is mostly based on binary classification algorithms that cannot provide doctors with location information. To solve this problem, this study proposes an end-to-end highly efficient algorithm for the detection of pneumonia based on a convolutional neural network—Pneumonia Yolo (PYolo). This algorithm is an improved version of the Yolov3 algorithm for X-ray image data of the lungs. Dilated convolution and an attention mechanism are used to improve the detection results of pneumonia lesions. In addition, double K-means is used to generate an anchor box to improve the localization accuracy. The algorithm obtained 46.84 mean average precision (mAP) on the X-ray image dataset provided by the Radiological Society of North America (RSNA), surpassing other detection algorithms. Thus, this study proposes an improved algorithm that can provide doctors with location information on lesions for the detection of pneumonia.
Preventing Venous Thromboembolism in Ambulatory Patients with Cancer: A Narrative Review
Authors: Rossel Anne , Robert-Ebadi Helia , Marti Christophe
Published: March 2020

Venous thromboembolism (VTE) is frequent among patients with cancer. Ambulatory cancer patients starting chemotherapy have a 5% to 10% risk of cancer associated thrombosis (CAT) within the first year after cancer diagnosis. This risk may vary according to patient characteristics, cancer location, cancer stage, or the type of chemotherapeutic regimen. Landmark studies evaluating thrombophrophylaxis with low molecular weight heparin (LMWH) for ambulatory cancer patients have shown a relative reduction in the rate of symptomatic VTE of about one half. However, the absolute risk reduction is modest among unselected patients given a rather low risk of events resulting in a number needed to treat (NNT) of 40 to 50. Moreover, this modest benefit is mitigated by a trend towards an increased risk of bleeding, and the economic and patient burden due to daily injections of LMWH. For these reasons, routine thromboprophylaxis is not recommended by expert societies. Advances in VTE risk stratification among cancer patients, and growing evidence regarding efficacy and safety of direct oral anticoagulants (DOACs) for the treatment and prevention of CAT have led to reconsider the paradigms of this risk–benefit assessment. This narrative review aims to summarize the recent evidence provided by randomized trials comparing DOACs to placebo in ambulatory cancer patients and its impact on expert recommendations and clinical practice.
Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies
Authors: Gilles Arnaud , Frechin Léo , Natchiar Kundhavai , Biondani Giulia , Loeffelholz Ottilie von , Holvec Samuel , Malaval Julie-Lisa , Winum Jean-Yves , Klaholz Bruno P. , Peyron Jean-François
Published: March 2020

The human 80S ribosome is the cellular nucleoprotein nanomachine in charge of protein synthesis that is profoundly affected during cancer transformation by oncogenic proteins and provides cancerous proliferating cells with proteins and therefore biomass. Indeed, cancer is associated with an increase in ribosome biogenesis and mutations in several ribosomal proteins genes are found in ribosomopathies, which are congenital diseases that display an elevated risk of cancer. Ribosomes and their biogenesis therefore represent attractive anti-cancer targets and several strategies are being developed to identify efficient and specific drugs. Homoharringtonine (HHT) is the only direct ribosome inhibitor currently used in clinics for cancer treatments, although many classical chemotherapeutic drugs also appear to impact on protein synthesis. Here we review the role of the human ribosome as a medical target in cancer, and how functional and structural analysis combined with chemical synthesis of new inhibitors can synergize. The possible existence of oncoribosomes is also discussed. The emerging idea is that targeting the human ribosome could not only allow the interference with cancer cell addiction towards protein synthesis and possibly induce their death but may also be highly valuable to decrease the levels of oncogenic proteins that display a high turnover rate (MYC, MCL1). Cryo-electron microscopy (cryo-EM) is an advanced method that allows the visualization of human ribosome complexes with factors and bound inhibitors to improve our understanding of their functioning mechanisms mode. Cryo-EM structures could greatly assist the foundation phase of a novel drug-design strategy. One goal would be to identify new specific and active molecules targeting the ribosome in cancer such as derivatives of cycloheximide, a well-known ribosome inhibitor.
Three-Dimensional Cell Culture Based on Magnetic Fields to Assemble Low-Grade Ovarian Carcinoma Cell Aggregates Containing Lymphocytes
Authors: Natânia de Souza-Araújo Caroline , Rodrigues Tonetti Cláudia , Cardoso Marcella Regina , Lucci de Angelo Andrade Liliana Aparecida , Fernandes da Silva Rodrigo , Romani Fernandes Luís Gustavo , Guimarães Fernando
Published: March 2020

There is a limited number of established ovarian cancer cell lines matching the low-grade serous histotype available for research purposes. Three-dimensional (3D) culture systems provide in vitro models with better tissue-like characteristics than two-dimensional (2D) systems. The goal in the study was to characterize the growth of a given low-grade serous ovarian carcinoma cell line in a 3D culture system conducted in a magnetic field. Moreover, the culture system was evaluated in respect to the assembly of malignant cell aggregates containing lymphocytes. CAISMOV24 cell line alone or mixed with human peripheral blood mononuclear cells (PBMC) were cultured using a commercially available 3D culture system designed for 24 well plates. Resulting cell aggregates revealed the intrinsic capacity of CAISMOV24 cells to assemble structures morphologically defined as papillary, and reflected molecular characteristics usually found in ovarian carcinomas. The contents of lymphocytes into co-cultured cell aggregates were significantly higher (p < 0.05) when NanoShuttle-conjugated PBMC were employed compared with non-conjugated PBMC. Moreover, lymphocyte subsets NK, T-CD4, T-CD8 and T-regulatory were successfully retrieved from co-cultured cell aggregates at 72h. Thus, the culture system allowed CAISMOV24 cell line to develop papillary-like cell aggregates containing lymphocytes.
Hydrogen Peroxide as a Green Oxidant for the Selective Catalytic Oxidation of Benzylic and Heterocyclic Alcohols in Different Media: An Overview
Authors: M. Heravi Majid , Ghalavand Nastaran , Hashemi Elaheh
Published: March 2020

Among a plethora of known and established oxidant in organic chemistry, hydrogen peroxide stands in a special position. It is commercially and inexpensively available, highly effective, selective, and more importantly it is compatible with current environmental concerns, dictated by principles of green chemistry. Several chemicals or their intermediates that are important in our daily life such as pharmaceuticals, flavors, fragrances, etc. are products of oxidation of alcohols. In this review, we introduce hydrogen peroxide as an effective, selective, green and privileged oxidant for the catalyzed oxidation of primary and secondary benzylic and heterocyclic alcohols to corresponding carbonyl compounds in different media such as aqueous media, under solvent-free conditions, various organic solvent, and dual-phase system.
Preparation of Coated Corrugated Box for Controlled-Release of Chlorine Dioxide and Its Application in Strawberry Preservation
Authors: Li Yuanyuan , Ren Dan , Xu Dan
Published: March 2020

Chlorine dioxide (ClO2) has received great attention as a nontoxic and efficient antimicrobial agent for the preservation of fresh fruits and vegetables. A novel two-layer coated corrugated box was developed to release gaseous ClO2 under the trigger of moisture in this study. The inner surface of the box was firstly coated with a mixture of polyvinyl alcohol-NaClO2-diatomite and then with chitosan acetic acid solution. Results showed that ClO2 was successfully released under high humidity due to the reaction of NaClO2, water vapor and acid. The concentration of released ClO2 increased with the increasing NaClO2 content in the coating, while the addition of diatomite stabilized and extended the release. To evaluate the preservation effect, strawberries were packed in the coated box and stored at room temperature. Compared with the control, the decay rate and weight loss of the strawberries packed in the coated box (9 g/L NaClO2) were reduced up to 21.88% and 6.84%, respectively. The surface color, firmness and nutrients content were also better maintained. Therefore, this coated corrugated box with the capability to release ClO2 under the trigger of moisture has great potential to be applied as an antimicrobial packaging for fresh fruits and vegetables.
(Perylene)3-(TCNQF1)2: Yet Another Member in the Series of Perylene–TCNQFx Polymorphic Charge Transfer Crystals
Authors: Salzillo Tommaso , Valle Raffaele G. Della , Venuti Elisabetta , Brillante Aldo , Kociok-Köhn Gabriele , Di Nuzzo Daniele , Masino Matteo , Girlando Alberto
Published: March 2020

The 3:2 Charge Transfer (CT) co-crystal (Perylene)3(TCNQF1)2 is grown by the Physical Vapor Transport (PVT) method, and characterized structurally and spectroscopically. Infrared analysis of the charge sensitive modes reveals a low degree of charge transfer (less than 0.1) between donor and acceptor molecules. The crystal is isostructural to the other 3:2 CT crystals formed by Perylene with TCNQF2 and TCNQF4, whereas such stoichiometry and packing is not known for the CT crystals with non-fluorinated TCNQ. The analysis of the isostructural family of 3:2 Perylene–TCNQFx (x = 1,2,4) co-crystal put in evidence the role of weak F…HC bonding in stabilizing this type of structure