bluuebunny/crossref_metadata_2025 huggingface dataset:
Trends in Hidradenitis Suppurativa Disease Severity and Quality of Life Outcome Measures: Scoping Review (Preprint)
Authors: Maghfour Jalal , Sivesind Torunn Elise , Dellavalle Robert Paul , Dunnick Cory
Published: February 2021

BACKGROUND

Although there has been an increase in the number of randomized controlled trials evaluating treatment efficacy for hidradenitis suppurativa (HS), instrument measurements of disease severity and quality of life (QoL) are varied, making the compilation of data and comparisons between studies a challenge for clinicians.

OBJECTIVE

We aimed to perform a systematic literature search to examine the recent trends in the use of disease severity and QoL outcome instruments in randomized controlled trials that have been conducted on patients with HS.

METHODS

A scoping review was conducted in February 2021. The PubMed, Embase, Web of Science, and Cochrane databases were used to identify all articles published from January 1964 to February 2021. In total, 41 articles were included in this systematic review.

RESULTS

The HS Clinical Response (HiSCR) score (18/41, 44%) was the most commonly used instrument for disease severity, followed by the Sartorius and Modified Sartorius scales (combined: 16/41, 39%). The Dermatology Life Quality Index (18/41, 44%) and visual analogue pain scales (12/41, 29%) were the most commonly used QoL outcome instruments in HS research.

CONCLUSIONS

Randomized controlled trials conducted from 2013 onward commonly used the validated HiSCR score, while older studies were more heterogeneous and less likely to use a validated scale. A few (6/18, 33%) QoL measures were validated instruments but were not specific to HS; therefore, they may not be representative of all factors that impact patients with HS.

CLINICALTRIAL

National Institute of Health Research PROSPERO CRD42020209582; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020209582
Enriching the Value of Patient Experience Feedback: Web-Based Dashboard Development Using Co-design and Heuristic Evaluation (Preprint)
Authors: Khanbhai Mustafa , Symons Joshua , Flott Kelsey , Harrison-White Stephanie , Spofforth Jamie , Klaber Robert , Manton David , Darzi Ara , Mayer Erik
Published: February 2021

BACKGROUND

There is an abundance of patient experience data held within health care organizations, but stakeholders and staff are often unable to use the output in a meaningful and timely way to improve care delivery. Dashboards, which use visualized data to summarize key patient experience feedback, have the potential to address these issues.

OBJECTIVE

The aim of this study is to develop a patient experience dashboard with an emphasis on Friends and Family Test (FFT) reporting, as per the national policy drive.

METHODS

A 2-stage approach was used—participatory co-design involving 20 co-designers to develop a dashboard prototype, followed by iterative dashboard testing. Language analysis was performed on free-text patient experience data from the FFT, and the themes and sentiments generated were used to populate the dashboard with associated FFT metrics. Heuristic evaluation and usability testing were conducted to refine the dashboard and assess user satisfaction using the system usability score.

RESULTS

The qualitative analysis from the co-design process informed the development of the dashboard prototype with key dashboard requirements and a significant preference for bubble chart display. The heuristic evaluation revealed that most cumulative scores had no usability problems (18/20, 90%), had cosmetic problems only (7/20, 35%), or had minor usability problems (5/20, 25%). The mean System Usability Scale score was 89.7 (SD 7.9), suggesting an excellent rating.

CONCLUSIONS

The growing capacity to collect and process patient experience data suggests that data visualization will be increasingly important in turning feedback into improvements to care. Through heuristic usability, we demonstrated that very large FFT data can be presented in a thematically driven, simple visual display without the loss of the nuances and still allow for the exploration of the original free-text comments. This study establishes guidance for optimizing the design of patient experience dashboards that health care providers find meaningful, which in turn drives patient-centered care.
Using Co-design in Mobile Health System Development: A Qualitative Study With Experts in Co-design and Mobile Health System Development (Preprint)
Authors: Noorbergen Tyler J , Adam Marc T P , Teubner Timm , Collins Clare E
Published: February 2021

BACKGROUND

The proliferation of mobile devices has enabled new ways of delivering health services through mobile health systems. Researchers and practitioners emphasize that the design of such systems is a complex endeavor with various pitfalls, including limited stakeholder involvement in design processes and the lack of integration into existing system landscapes. Co-design is an approach used to address these pitfalls. By recognizing users as experts of their own experience, co-design directly involves users in the design process and provides them an active role in knowledge development, idea generation, and concept development.

OBJECTIVE

Despite the existence of a rich body of literature on co-design methodologies, limited research exists to guide the co-design of mobile health (mHealth) systems. This study aims to contextualize an existing co-design framework for mHealth applications and construct guidelines to address common challenges of co-designing mHealth systems.

METHODS

Tapping into the knowledge and experience of experts in co-design and mHealth systems development, we conducted an exploratory qualitative study consisting of 16 semistructured interviews. Thereby, a constructivist ontological position was adopted while acknowledging the socially constructed nature of reality in mHealth system development. Purposive sampling across web-based platforms (eg, Google Scholar and ResearchGate) and publications by authors with co-design experience in mHealth were used to recruit co-design method experts (n=8) and mHealth system developers (n=8). Data were analyzed using thematic analysis along with our objectives of contextualizing the co-design framework and constructing guidelines for applying co-design to mHealth systems development.

RESULTS

The contextualized framework captures important considerations of the mHealth context, including dedicated prototyping and implementation phases, and an emphasis on immersion in real-world contexts. In addition, 7 guidelines were constructed that directly pertain to mHealth: understanding stakeholder vulnerabilities and diversity, health behavior change, co-design facilitators, immersion in the mHealth ecosystem, postdesign advocates, health-specific evaluation criteria, and usage data and contextual research to understand impact.

CONCLUSIONS

System designers encounter unique challenges when engaging in mHealth systems development. The contextualized co-design framework and constructed guidelines have the potential to serve as a shared frame of reference to guide the co-design of mHealth systems and facilitate interdisciplinary collaboration at the nexus of information technology and health research.
Effectiveness of Immersive Virtual Reality in Alleviating Pain and Anxiety in Children during Immunization in Primary Care: A Pilot Randomized Controlled Trial (Preprint)
Authors: Chang Zi Ying , Kang Gary Chun-Yun , Koh Eileen Yi Ling , Fong Rodney Jin Kai , Tang Jiasheng , Goh Chi Keong , Tan Ngiap Chuan
Published: February 2021

BACKGROUND

Paediatric immunization is often associated with significant fear and anxiety among the older children and their parents. Their distress may potentially affect their adherence to the childhood immunization schedule and the acceptance of other recommended vaccines by physicians.

OBJECTIVE

The study primarily aimed to assess the feasibility of using immersive virtual reality (VR) during immunization in children in primary care. The secondary aim was to determine the effectiveness of immersive VR in alleviating pain and anxiety among children, reduction of anxiety of their parents and attending nurses during immunization compared to usual care without VR.

METHODS

A pilot open-label randomized control trial was conducted at a public primary care clinic in Singapore. Thirty children, aged 4-10 years were randomised to an intervention group (n=15) using VR and a control group (n=15) without VR during immunization. Feasibility was assessed by the response rate to the use of VR. The Faces Pain Scale-Revised (FPS-R) and the Children’s Fear Scale (CFS) were used to determine their pain and anxiety respectively before and after the immunization. The anxiety level of their accompanying parents and attending nurses were evaluated using Visual Analogue Scale (VAS) prior and post-immunization of these children. Change in FPS-R and CFS scores, and anxiety assessment for parents and nurses were assessed using Mann-Whitney U test. Wilcoxon signed rank test was used to assess the difference in the nurses’ experience of using the VR application.

RESULTS

One child refused to use the VR equipment, constituting a rejection rate of 6.7% (1/15) but no adverse event occurred in the intervention arm. The overall response rate of 88% (30/34) when the parents were approached to participate in the study, indicating feasibility of using VR in childhood immunization. In the intervention group compared to the control group, the change in scores for CFS (median -1, IQR -2 to 0; P=.04), parental VAS (median -4, IQR -5 to -1; P=.04) were significantly decreased. After immunization, nurses scored favourably for VR, in terms of simplicity (median 9.5, IQR 5.72 to 10; P=.01), acceptability (median 10, IQR 5 to 10; P=.005) and willingness to use VR in the future (median 10, IQR 5 to 10; P=.02).

CONCLUSIONS

Immersive VR is feasible, safe and effective in alleviating anxiety among the children, parents and their attending nurses. Nurses viewed the application of VR in childhood immunization favorably.

CLINICALTRIAL

ClinicalTrials.gov NCT04748367 ; https://clinicaltrials.gov/ct2/show/NCT04748367
Using Emerging Telehealth Technology as a Future Model in Vietnam During the COVID-19 Pandemic: Practical Experience From Phutho General Hospital (Preprint)
Authors: Nguyen Ngoc Huy , Nguyen An Quang , Ha Van Thi Bich , Duong Phuong Xuan , Nguyen Thong Van
Published: February 2021

UNSTRUCTURED

Telehealth has emerged as a model of modern technology for health care services in Vietnam during the COVID-19 pandemic. To actively prevent the outbreak of COVID-19 by using a national digital transformation program, the Vietnamese Ministry of Health launched project 2628/Quyet dinh-Bo y te, which approved a scheme for remote medical examinations and treatments for 2020 to 2025. The project aims to connect 1000 hospitals to strengthen the quality of medical services by using the expertise of central hospitals to support rural areas via provincial hospitals. Phutho General Hospital (PGH) is one of leading provincial hospitals that participated in and applied the early telehealth systems in Vietnam. By using telehealth systems, PGH can offer valuable support to doctors’ activities by streamlining and facilitating their work. Telehealth was demonstrated to be feasible, acceptable, and effective at PGH in Vietnam, and it resulted in considerable improvements in health care outcomes. The COVID-19 pandemic has facilitated the acceleration and enhancement of telehealth in Vietnam. The success of telehealth in Phutho may be a useful reference for other parts of the world. However, this telehealth system focuses on the connectivity among doctors rather than the connectivity between doctors and patients, which is an area that needs further assessment.
ОЦЕНКА И ПРОГНОЗ РАЗВИТИЯ МИРОВОГО И ОТЕЧЕСТВЕННОГО РЫНКА НАВИГАЦИОНОЙ АППАРТУРЫ И УСЛУГ. ТЕНДЕНЦИИ В СОЗДАНИИ ЭКБ И НАВИГАЦИОННОЙ АППАРАТУРЫ ПОТРЕБИТЕЛЕЙ. МЕРЫ ГОСУДАРСТВЕННОЙ ПОДДЕРЖКИ ОТЕЧЕСТВЕННЫХ РАЗРАБОТЧИКОВ И ПРОИЗВОДИТЕЛЕЙ
Authors: Кондрашов З.К. , Корнеев И.Л.
Published: February 2021

Дан прогноз требований на мировом и отечественном рынке навигационнной аппаратуры на период до 2025 года. Приведены результаты выполнения ФЦП «Поддержание, развитие и использование навигационной системы ГЛОНАСС на 2012-2020 годы» в части Минпромторга России и предложения по выполнению новой ФЦП на 2021-2030 годы.
USB 3.0 ФЛЕШ-НАКОПИТЕЛЬ. ОСНОВНЫЕ ПРИНЦИПЫ РАБОТЫ, ТЕХНИЧЕСКИЕ ОСОБЕННОСТИ РЕАЛИЗАЦИИ
Authors: Руткевич А.В. , Воронков Д.И. , Шишкин Г.В.
Published: February 2021

Рассматриваются основные принципы работы накопителя на основе NAND флеш-памяти с интерфейсом USB 3.0, технические особенности реализации контроллера флеш-накопителя и его встроенного программного обеспечения. Приведены результаты тестирования флеш-накопителя разработки НПП «Цифровые решения».
El derecho a la salud en el Protocolo Nacional para la atención integral de las personas con derecho a la interrupción legal del embarazo de la República Argentina:
un estudio desde el Derecho Internacional de los Derechos Humanos
Authors: Brichetti Florencia Mariana
Published: February 2021

El problema que representa el acceso al aborto no punible en Argentina ha sido abordado desde diversos ámbitos y disciplinas. El surgimiento del fallo FAL de la Corte Suprema de Justicia (2012) ha motivado el dictado y modificación de protocolos hospitalarios a nivel provincial con la finalidad de establecer cómo deberán actuar los establecimientos de salud al momento en que se solicita la práctica de un aborto no punible, para garantizar el acceso al derecho a la salud. Sin embargo, la academia continúa llamando la atención sobre la alarmante falta de apego que existe en los hechos a los estándares de derechos humanos en el acceso a la práctica del aborto legal. Para aportar a este debate, es nuestra intención indagar si el Protocolo nacional para la atención integral de las personas con derecho a la interrupción legal del embarazo, cumple con los estándares internacionales de derechos humanos relativos al derecho a la salud.
GENDER PERSPECTIVE AND NEWMAN'S THEORY IN ERROR ANALYSIS OF STUDENTS' ANSWERS IN RATIO AND PROPORTION
Authors: Hanifah Nida Fathiya , Hidayat Wahyu , Aripin Usman
Published: February 2021

This research was conducted to find out how the gender perspective affects the mistakes made by students in the ratio and proportion questions. Mindset’s differences between male and female will affect how they solve problems and it will also affect their mathematics learning outcomes. Errors made by students were analyzed using the Newman error analysis indicator. Error analysis indicators used are reading errors, misunderstanding errors, transformation errors, process errors, and error writing answers (encoding). This research uses descriptive qualitative research method. This research was conducted at SMPN 2 Cimahi. The instruments in this study were test and non-test questions. It can be concluded from this research that there are differences between male and female students when working on ratio and proportion concept questions based on the mistakes they’ve made. The most common mistakes made by male students are mistakes in the process of writing answers. This error occurs because they do not write down the complete answer details, it’s because male tend to be simpler in solving problems. The most common mistake made by female is an error in understanding. It’s because female tend to use logic-less when understanding the mathematical problems presented in the questions.
ERRORS ANALYSIS OF STUDENTS IN SOLVING VOLUME OF THE SOLID OF REVOLUTION PROBLEM IN TERM OF CRITICAL THINKING ASPECTS
Authors: Kusumaningrum Betty , Irfan Muhammad , Zainnur Wijayanto
Published: February 2021

Students of mathematics education need to have a good understanding in solving integral calculus problems, but often have difficulty in understanding the subject material. The difficulties can be seen from the mistakes made by students when solving the problems. This article aims to analyze the errors of students in learning integral calculus especially in the subject of volume of the solid of revolution in terms of critical thinking aspects. This research is a qualitative descriptive study involving twenty-four of 6th-semester students of mathematics education at a private university in Yogyakarta. The research subjects were chosen purposively by considering: student errors in determining the volume of the solid of revolutions with integral techniques in terms of critical thinking aspect. The findings of this study indicate, student errors in determining the function of integrals, write down the rules of integral writing, misunderstanding in algebraic concepts, adding constants, write down limits and sigma notations, determine integration methods, determine boundaries integration, writing in integral sign, and error in determining the radius of the solid of revolution.
IMPROVING STUDENTS LEARNING OUTCOMES IN BLENDED LEARNING THROUGH THE USE OF ANIMATED VIDEO
Authors: Puspaningtyas Nicky Dwi , Marchamah Ulfa
Published: February 2021

This quantitative study aims to determine the improvement of student learning outcomes in blended learning through the use of animated videos. The study was conducted on 35 students of Universitas Teknokrat Indonesia in the Business Mathematics course. Pretest and posttest are given to subjects to determine learning outcomes before and after treatment. Obtained the average pretest and posttest amounted to 29.4 and 80.4, respectively. Based on the results of Man-Whitney tests, it can be concluded that the mean pretest and posttest scores differ significantly. This means that the use of animated videos in learning Business Mathematics can improve student learning outcomes.
IMPROVING STUDENTS’ COMPETENCY ON FINANCIAL MATHEMATICS LEARNING BY APPLYING POLYAS’ MODEL HEURISTIC STRATEGY
Authors: Simarmata Justin Eduardo , Lailin Hijriani
Published: February 2021

The research aims to depict students’ ability in solving mathematical problems based on Polya’s heuristic. Descriptive qualitative was used as a method in this research. Data were collected by observation, test, and interview. Based on the result of analysis obtained that the students with low level prior knowledge think heuristically in solving the problem solving test. For the students with medium level prior knowledge, the students think algorithmically and couldn’t solve the problem solving test imperfectly. Furthermore, the students with high level prior knowledge think algorithmically in solving the problem solving mathematics test and the other words, the students could solve the problem solving test well and fluently.
DEVELOPMENT OF WEB-BASED LEARNING IMPLEMENTATION AND ANDROID APPLICATIONS TO BRING TEACHER CAPABILITY
Authors: Setyansah Reza Kusuma , Andria
Published: February 2021

This study aims to determine the results of the process of developing a web-based e-learning implementation book and an android application, as a way to hone the teaching skills of prospective teachers. The instruments in this study were observation sheets, books, and questionnaires. Based on the achievement of the product, product evaluation is needed including validation of material experts and media experts. The stages in this study with the ADDIE model are (1) analysis, (2) design, (3) development, (4) implementation, and (5) evaluation. The results of this study obtained that the web-based e-learning implementation book and android application have fulfilled (1) Validation data with the average results obtained from the media validation sheet from media experts 93.67% and 85 material experts, 33%. (2) seen a positive influence from the results of the post-test with a percentage of 91.68% and (3) shows the response of prospective teachers after using e-learning books in the main field test showed a percentage of 82.68% so that they can hone their ability to teach independently.
Association between Matrix Metalloproteinas-2 Gene Variants and Pathogenesis of Breast Cancer in Sera of Iraqi Women
Authors: Abbas Yammamah Jawad , Al-Tu'ma Fadhil Jawad , Al-Hemerri Alaa Fraq
Published: February 2021

Objective: The current study aims to investigate the role of MMP-2 in breast cancer pathogenesis in Iraqi women.

Methods: A forty one women with breast cancer and 45 control women were included in this case-control study. Body mass index, age, smoking; married status, tumor size, degree, subtype, lymph node status, pre and postmenopesua included the phenotypic results. The polymerase chain reaction-PCR-allele specific restriction was used to observe the rs243865 polymorphism. Genomic DNA was extracted from whole blood and genotyping with specific prefixes for amplification of the MMP-2 gene was accomplished as enzyme-restricted PCR products were digested, followed by electrophoresis on 1.5% agarose gel. In order to interpret the researchers' results, numerous statistical analyses were applied.

Results: The amplicon size of MMP-2 gene was 304 bp, and following its amplification reactions by allelic specific PCR. The amplification product for MMP-2 gene amplification SNP rs243865 gene polymorphism results exhibited one band of 304 bp, two bands of 304 bp and one band 304 bp for individuals have genotype as wild type (CC), homozygous (TT) and heterozygous (CT), respectively. Genotype frequencies of rs243865 polymorphism were found to be consistent with Hardyâ€“Weinberg equilibrium. Allele frequencies of C allele was 0.57, and the T allele was only 0.43 in cases of breast cancer women patient, while the frequencies of CC, CT, and TT genotypes of the rs243865 SNP were statistically significant as 31.7%, 51.2%, 17.1% respectively. Allele frequencies of C and T were 0.78 and 0.22 for the control group, respectively, the heterozygous genotype (CT) was significantly increased the risk of breast cancer women (OR=0.3, 95% CI;0.12 â€“ 0.8 , Pâ‰¤ 0.05) with respect to those of the CC wild type.  The TT genotype significantly raised the risk of breast cancer women by (OR = 0.2, 95% CI; 0.04 â€“ 0.9, Pâ‰¤ 0.05).

Conclusion: In women with breast cancer, MMP-2 expression is highly association were observed with positive lymph node, histological classification of breast cancer (ll) higher than other classes, and advanced clinical process (ll).
Resource requirements for efficient quantum communication using all-photonic graph states generated from a few matter qubits
Authors: Hilaire Paul , Barnes Edwin , Economou Sophia E.
Published: February 2021

Quantum communication technologies show great promise for applications ranging from the secure transmission of secret messages to distributed quantum computing. Due to fiber losses, long-distance quantum communication requires the use of quantum repeaters, for which there exist quantum memory-based schemes and all-photonic schemes. While all-photonic approaches based on graph states generated from linear optics avoid coherence time issues associated with memories, they outperform repeater-less protocols only at the expense of a prohibitively large overhead in resources. Here, we consider using matter qubits to produce the photonic graph states and analyze in detail the trade-off between resources and performance, as characterized by the achievable secret key rate per matter qubit. We show that fast two-qubit entangling gates between matter qubits and high photon collection and detection efficiencies are the main ingredients needed for the all-photonic protocol to outperform both repeater-less and memory-based schemes.
Laryngeal suction tube: A novel technique for tracheal ventilation in an obstructed airway in a child with respiratory papillomatosis
Authors: Saniasiaya Jeyasakthy , Lim Siu Min , Kulasegarah Jeyanthi
Published: February 2021

Background Airway obstruction in a child requires expedite management in
addition to comprehensive discussion between the Otolaryngology and
Anaesthesiology team to formulate a treatment plan to ensure safe
airway. Juvenile-onset recurrent respiratory papillomatosis (JORRP) is
an exophytic benign laryngeal lesion which poses a great challenge when
presented with respiratory distress. Objective: This paper presents a
novel, safe and cost-effective approach to temporary tracheal
ventilation of the obstructed airway in a child with juvenile-onset
recurrent respiratory papillomatosis using the laryngeal suction tube
connected to general anaesthetic (GA) machine. Result and Conclusion
Rigid laryngeal suction tube is placed through the side-port of Lindholm
laryngoscope and connected to breathing circuit of GA machine via
modification of the suction tubing and endotracheal tube (ETT) 15mm male
connector. Manual bagging ventilation with 100% FiO2 achieved good
oxygenation throughout the debulking of the papilloma without hindering
the surgical field. Our technique utilizes the readily available
equipment whilst enabling safe anaesthesia and providing good surgical
field during excision of obstructive papillomatous airway lesion.
Cognition in Pediatric SDB - Yes, No, Maybe?
Authors: Hunter Scott , Garagozzo Ariana
Published: February 2021

Numerous studies in the past 10 years have reported on the
neurocognitive sequalae of pediatric Sleep Disordered Breathing (SDB).
Variations in criteria used to define SDB in conjunction with the wide
variety of neuropsychological measures selected to evaluate cognitive
consequences of SDB have resulted in discrepancies within the
literature. This review summarizes the extant literature regarding
cognitive effects of pediatric SDB across domains of global
intelligence, attention, executive function, memory, language, and
visuospatial ability. This review also addresses the proposed etiology
underlying neurocognitive consequences of pediatric SDB. The differences
in findings across the literature are highlighted and discussed
throughout.
Production time and user satisfaction of 3-dimensional printed orthoses for chronic hand conditions compared with conventional orthoses: A prospective case series
Authors: Oud Tanja , Kerkum Yvette , De Groot Peter , Gijsbers Harm , Nollet Frans , Brehm Merel-Anne
Published: February 2021

Objective: Hand orthoses are often prescribed for persons with chronic hand and wrist impairments. This study assessed the feasibility, in terms of production time and user satisfaction, of 3-dimensional printed hand orthoses compared with conventional hand orthoses for this population.
Methods: In this prospective case series, both a conventional hand orthosis and a 3-dimensional printed hand orthosis were manufactured for 10 participants. Production time (in minutes) of each orthosis was recorded. Each orthosis was worn for one week, after which participants completed a self-designed questionnaire on satisfaction, scored on a 5-point Likert scale. Functionality and orthosis preference were also assessed.
Results: The mean (standard deviation (SD)) production time for the 3-dimensional printed orthoses, of 112 (11.0) min, was significantly shorter compared with 239 (29.2) min for the conventional or-thoses (95% confidence interval (95% CI) 71?182 min, p?=?0.001). Satisfaction scores were similar for both orthoses, except for comfort item ?fitting method?, which was rated significantly higher for scanning compared with casting (median [IQR] score: 5 [0.0]; 4 [2.0], p?=?0.034). Functionality and orthosis preference were rated similar for both orthoses.
Conclusion: As the production time was halved, user satisfaction similar, and scanning experienced as slightly more comfortable than casting, 3-dimensional printed hand orthoses seem feasible and potentially beneficial for use in people with chronic hand and wrist impairments.
Several Variables Response to 2.2% Intra-Articular Injections of Hyaluronic Acid
Authors: Abdullah Basser Ali
Published: February 2021

Objectives of the research: to assess the effects of TMJ 2.2 hyaluronic acid injection on following TMJ pain, TMJ clicking, maximum opening capacity and lateral mandibular movements. This study include one hundred patients (77females and 23males) whom complain from clicking and pain at their TMJ with or without limitation of mandibular movements. The age ranged between 9-65 years old. Hyaluronic acid 2.2% were used for intra- articular injection unilaterally at the upper compartment of the most painful TMJ. Assessment of pain was done by using the visual analogue scale (0-10), the intensity of clicking was evaluated by stethoscope using basser clicking score, lateral movements were calculated by using ruler and recorded into special case sheet, and any complications that reported by the patients were recorded. These data were recorded before treatment and one, two, three weeks post injections, also one month after the last injection. SPSS (statistical package of social science) window 11.5 version was used for statistical investigation with chi square and paired T tests with P ≤ 0.001 as a significant value. The outcome of this study reveals that age cluster between (21-30) years was the most prevailing age, it signify (29%) of the entire trial, whereas the age group over 50 years was the least represented age group, it signify 7%, Female were presented in this study more often than males at a ratio of (3.3 -1). Regarding TMJ pain, there were significant differences (P≤ 0.001) before and after intra-articular drug administration. Significant differences P≤ 0.001were found in clicking scores means before and after intra-articular HA injections there were significant differences P≤ 0.001 in maximum opening capacity means before and after TMJ injections. There were significant differences in both lateral left and right movements means P ≤ 0.001 before and after TMJ injections of hyaluronic acid. This study conclude that HA 2.2% TMJ injection is an effective method in treating different TMJ diseases including temoporomandibular disorders, it reduce pain, clicking and improve mandibular motion, their effect persist even one month beyond last injection, it is effective, safe, painless, not costly, with no side effects like steroid, with no complications, usually no need to another drugs following injections like antibiotic and analgesic. We recommend that this modalities as the best treatment for TMDs. Also we conclude that females seek treatment more often than males at a ratio 3.3:1.
Teledentistry; Escalating Horizon in COVID-19
Authors: Kaur Ishdeep
Published: February 2021

Teledentistry has emerged as an efficacious technique of extending oral care services to the patients remotely assisted by the sophisticated technology of telecommunication. Over time, teledentistry has established itself as a convenient, labour saving, time effective and an economical alternative alongside bridging the inequality of the available services between the urban and rural demographics. This review explores the evolution and applications of teledentistry and how it has been instrumental in attending to the needs of patients specifically in times of a roaring pandemic where inpatient examination and treatment in a dental facility was not feasible or stalled as a precautionary measure. Not only does it assists in attending to emergencies and routine consults but also in screening and reporting of any plausible cases with COVID infection.
On the Possible Beneficial Role for the Regular Use of Potent Mouthwash Solutions as a Preventive Measure for Covid19 Transmission; Invoking the Evolutionary Biology and Game Theory
Authors: Mukhtar Khalid
Published: February 2021

In vitro studies demonstrated bactericidal and virucidal role for some of the over-the-counter mouthwash solutions. Meanwhile, Game theory and evolutionary biology suggests that inhibiting cooperation -reciprocal altruism- between two organisms can negatively affect their survival, based on a set of relevant publications, it is proposed here that "SARS-COV-2" may be relying on an "accomplice"; be it a certain organism (e.g. bacterial species), or a state of dysbiosis in general. On this premise, the regular use of potent disinfectant, through the repeated reduction in microbial load, may be able to induce a strain sufficient to inhibit reciprocal altruism, and hence halt the progression of the disease, as observed in the majority of those tested positive worldwide, yet with mild or no symptoms. We cite a group of observations related to COVID, that can be justified by the complicit hypothesis, predict a rather preventive than therapeutic advantage, suggestive for a possible role for the regular use of potent mouthwash as an additional control measure in the community level.
Examples of Change and Practice in University-Affiliated Medical Libraries
Authors: Çolaklar Huriye
Published: February 2021

Medical sciences constantly conduct research on combating diseases, healing, developing treatment methods, preventing diseases, and increasing the quality of health. Medical education, which supports and fosters medical sciences, has a very long history and it ensures that well-qualified and competent physicians are trained in the medical faculties of universities. States pay particular attention to health services and education in their health policies so as to have healthy individuals. Today, it is inevitable for medical librarians to participate in clinical practice, take part in scientific research activities, support medical education, and take part in university hospitals as an integral part of the medical team, both in the delivery of medical education and in the provision of quality health care. Physicians, academics, students, and other healthcare professionals should receive a high-quality medical education, as well as obtain accurate, up-to-date, evidence-based information about their field in the most economical, fastest and easiest way. Medical libraries provide the evidence-based, medical information and documentation required in this field. The services offered in medical libraries and the processes of managing medical information obtained through their own information resources have unique features. In the current study, the information seeking behaviors of medical library users, the characteristics of the information they seek and the information services offered in these libraries were analyzed using the method of description and literature review. To present the exemplary information services practices of some important and large medical libraries both in Turkey and the world, their web pages were analyzed by their content, collection, design, services and innovations. The change of medical libraries in the 21st century and the role of medical librarians were also analyzed. Based on the results, it can be highlighted that besides offering information management, medical libraries offer new services, while assuming new roles and responsibilities by drawing on evidence-based medicine and technological developments.
WOMAN STRUGGLE IN PAULO COELHO’S THE SPY
Authors: NOVIYANTI EKA , SARAGIH AMRIN , NATSIR MUHAMMAD
Published: February 2021

This study discussed woman struggle in Paulo Coelho’s The Spy. The objectives were to find out the kinds of woman’s struggle in Novel The Spy, the ways the main character struggles to fulfill her needs, and the reasons why the main character struggle in the way she did. This study used descriptive qualitative method. This study used Maslow (1987) theory to analyze the kinds of woman’s struggle and the ways the main character struggles to fulfill her needs that she had faced and elaborated the reasons by using theory of ambition. The result of this study can be concluded in some aspects. First, the kinds of woman’s struggle found in Novel The Spy in fulfilling the human needs, namely: Struggle for Survival, Struggle to Reach the Dream, Struggle for Love & Relationship, Struggle in Getting A Good Reputation and Struggle to be Independent Woman. Second, the ways the main character struggles to fulfilling her needs are exchange sex with favors and money, making relations with men from the higher classes and to be a Spy. Third, the reasons why the main character struggle are because of her ambition to become a Free Woman and influenced by author’s background.
Tourism and local lore activities as a form of studying the local socio-cultural environment
Authors: Krivosheeva Tatyana Mikhailovna
Published: February 2021

In the article, the term “authenticity” is considered as a conceptual element in contemporary tourism, which has significant importance when forming the territorial tourist product and determining a set of sustainable components of the socio-cultural environment. The article raises the issues of updating approaches to the development of the local lore movement and the formation of a "new local history", as well as determines its connection with territorial authenticity and the development of the geocultural specifics of the territory. The authors have conducted a retrospective review of the interpretation of the term "local history" in Russian and foreign practice. The tourism and local lore activities are considered in the context of "new local history", development of tourist and excursion services, and related activities. The authors have proposed a list of urgent problems of tourism and local lore activities at the current stage and designated the implementation features of each problem, namely cognitive, value-oriented, transformative, and communicative task.
Korney Ivanovich Chukovsky about the Russian translation reception of Shakespeare (article two)
Authors: Morozova Svetlana N. , Zhatkin Dmitry N.
Published: February 2021

The first half of the 20th century in the Russian translation reception of Shakespeare was marked by the emerging of translations by B.L. Pasternak, S. Ya. Marshak, A.D. Radlova, W.V. Levik, I.B. Mandelstam. Characterizing their transcriptions, K.I. Chukovsky not only substantiated the artistic manner and creative position of the translators, but also presented his understanding of individual shortcomings and, conversely, successful findings. The articles «The Crippled Shakespeare», «Asthma in Desdemona» (1940) reflect his sharp rejection of the approach of A.D. Radlova to the interpretation of Shakespeare’s plays, he notes the mistakes made by the translator when working with the original texts. K.I. Chukovsky positively spoke about «Richard II» by I.B. Mandelstam; he considered its undoubted merit to be his free style and the absence of a formalist approach in observing certain parameters of the original text. The most complete features of the translation concept of K.I. Chukovsky are disclosed on the example of his translation of Shakespeare’s comedy «Love’s Labor’s Lost» (1945), which has been repeatedly staged in the theater.
Fractional order differential inclusions on an unbounded domain with infinite delay
Authors: Helal Mohamed
Published: February 2021

We provide sufficient conditions for the existence of solutions to initial value problems, for partial hyperbolic differential inclusions of fractional order involving Caputo fractional derivative with infinite delay by applying the nonlinear alternative of Frigon type for multivalued admissible contraction in Frechet spaces.
Coefficient inequalities for certain classes of analytic function using q−derivatives
Authors: Varadharajan S. , Selvaraj C. , Karthikeyan K. R.
Published: February 2021

We introduce and we study certain classes of analytic functions which are defined by making use of the q-derivative operator. Coefficient inequalities for functions in these classes are discussed. Some interesting consequences of the results are also pointed out.
THE WONDER FOOD MUSEUM STORY: CELEBRATING MALAYSIA’S FOOD CULTURE AND CULINARY HERITAGE
Authors: SER ShawHong
Published: February 2021

Although thematic museums centered around food culture and culinary heritage have beenaround for decades, the concept of food museum is still fairly new in Southeast Asia. Only in2015, the first food-oriented museum – “Wonder Food Museum” was established in Penang,Malaysia. Since its establishment, the museum has received positive feedback from bothlocal and international visitors. From 2017 to 2019, the museum has been selected as therecipient of the Certificate of Excellence by international well renowned Travel organization -TripAdvisor Inc. Meanwhile, the museum’s contribution to the state’s cultural and tourismdevelopment has also been recognized by the state authority. In 2017 and 2019, the museumwas awarded the ‘Top Museum Award (Unique Concept)’, and ‘Best Tourism(Museum)Award’ by the INPenang International Awards respectively. By and large, WonderFood Museum is currently one of the most outstanding museums in Malaysia and a wellknownattraction in Penang. In this paper, to response on the research scholarly interest inmuseum tourism in Southeast Asia, the researcher has made an attempt to document thedevelopment of Wonder Food Museum from 2015 to 2019. The museum’s curatorial concept,exhibits production, exhibition planning and its overall management will be discussed andanalyzed. As the aforementioned this paper will provide insights into an understanding of foodmuseum’s development in Malaysia.

Keywords: Food museum, food culture, culinary heritage, Malaysia’s museum, museumtourism, interactive museum
The influence of the preoperative rehabilitation on the results of anatomical lung resections
Authors: Romanikhin A. I. , Gorbunkov S. D. , Kovalev M. G. , Akopov A. L.
Published: February 2021

The objective was to investigate the efficiency of the preoperative rehabilitation for patients with planned anatomical lung resections.

Methods and materials.The study included 92 patients aged 27 to 87 years (mean age (63±10.8) years), 25 women (27.2 %) and 67 men (72.8 %) who underwent anatomical lung resections (79 patients, 85.9 % for lung cancer). Group 1 (39 patients – 42 %) included patients who did not smoke or quitted smoking at least 2 months before the operation. Also, they complied with the recommendations regarding respiratory gymnastics and the use of exercise and induction spirometers in full for at least 14 days. All patients who continued smoking or abandoned it less than 2 weeks before the operation, did not use breathing exercises, were included in group 2 (53 patients – 58 %).

Results. Significant difference was found in the number of complications in the studied groups (the average number of complications in one patient in group 1 was (0.46±0.8), in group 2 – (1.47±1.5), p = 0.03). The difference was found in the duration of hospitalization (19.7 days in group 1 and 25.3 days in group 2, p <0.017), in the length of stay in the ICU ((1.6±0.9) days in group 1 versus (3.4±5.9) days in group 2, p = 0.011). The early postoperative period for patients of group 1 was more favorable regardless of the presence and severity of the course of concomitant chronic obstructive pulmonary disease.

Conclusions. Comprehensive preoperative rehabilitation helps to reduce the number and severity of manifestations of complications after anatomical lung resections.
Assessment of the physical, social and value component of health in the structure of healthy lifestyle among the student youth of medical university
Authors: Arkhipova L. Yu. , Svishcheva A. A.
Published: February 2021

Introduction. Young people act as a basic component of the security of society. Physical development data is an indicator of the level of health of the population. Studying at the university coincides with the reproductive period. Adverse effects on the body of young people during this period can negatively affect the health of the next generation. Physical culture and sports activities allow students to integrate effectively into the educational space of the university.

The objective of our study was to assess the morphological and medical and social characteristics of the physical development of the student youth in Saratov.

Methods and materials. The study was conducted in 2018–2019 at the base of the department of physical therapy, sports medicine and physiotherapy in Saratov State Medical University named after V. I. Razumovsky. Respondents were the students of the Saratov State Medical University named after V. I. Razumovsky as the most promising group of young people in the preservation of reproductive health. Anthropometric parameters were carried out in accordance with the recommendations of V. V. Bunak. The study included anthropometric parameters: body weight, body length, and mass-growth correlation. We analyzed the values of the method «Diagnosing the real structure of value orientations». Analysis of self assessment of the level of health and assessment of their healthy lifestyle by the author’s questionnaire of a closed type.

Results. Data of anthropometric parameters of physical development and body mass index of boys 2018–2019 tends to be overweight. S.S. Bubnova’s most preferred values for medical students are «help and mercy for people», «recognition and respect for others» and «pleasant pastime» that does not correlate with health care. Analysis of value priorities in the healthy lifestyle of medical students showed that the majority of respondents to health is not quite high role.

Conclusion. Motivated preservation of individual health and active position of the university in the case of healthy lifestyle during the student studies can have a beneficial effect in the formation of health behavior of young people. It is necessary to establish the possibility of regular, accessible and balanced nutrition of students during the study at the university.
Odontology teaching at the Petrograd Medical Institute in 1918 – early 1920s.
Authors: Zimin I. V. , Zhuravlyov A. A.
Published: February 2021

The article considers the changes that took place in the Petrograd Medical Institute during the Civil War in the teaching of odontology. Changes affected the teaching staff, as well as students. The growth of the influence of the Party cell in the Institute contributed to the withdrawal of «bourgeois» teachers.
Gastrointestinal symptoms as an indicator of progression of pulmonary involvement in patients with COVID-19
Authors: Altunisik Erman , Baykan Ali Haydar , Sayiner Hakan Sezgin , Erturk Mehmet Sukru
Published: February 2021

Background:

While the patients with coronavirus disease 2019 typically present with respiratory illness, some patients also report gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain. In this case study, four different cases with the progression of pulmonary computed tomography (CT) findings following the onset of gastrointestinal symptoms are presented.

Case presentation:

Case 1, A 37-year-old male patient presented with fever, cough, fatigue, muscle and joint pain. On the fifth day of treatment, gastrointestinal symptoms including anorexia, nausea and vomiting were observed. A follow-up chest CT revealed progression in pulmonary involvement. Case 2, A 46-year-old male patient presented with fever, shortness of breath, muscle and joint pain. On the fourth day of treatment, gastrointestinal symptoms including anorexia, nausea and vomiting were observed. A follow-up chest CT revealed progression of pulmonary findings in both lungs. Case 3, A 50-year-old male presented with no symptoms other than dry cough. On the fourth day of treatment, gastrointestinal symptoms including anorexia, nausea and vomiting were observed. A follow-up chest CT revealed bilateral peripherally ground-glass and consolidation areas. Case 4, A 34-year-old female patient presented with fever, cough, fatigue, muscle and joint pain. On the third day of the treatment, gastrointestinal symptoms including anorexia, nausea, vomiting and diarrhea were observed. A follow-up chest CT revealed bilateral progression of pulmonary findings.

Conclusion:

Many studies reported that patients with gastrointestinal symptoms have a more serious clinical course than patients without these symptoms. No study has yet been presented to the literature in which this clinical situation is supported by radiological findings.