bluuebunny/crossref_metadata_2025 huggingface dataset:
Global value chains between Russia and Belarus in new geopolitical conditions
Authors:   Financial University under the Government of the Russian Federation, Arefyev Petr V.
Published: June 2023

The article examines some aspects of building global value chains between Russia and Belarus in the new geopolitical conditions, indicating their impact on the human capital of both countries. The relevance of the topic at the moment is high, as the difficult geopolitical situation persists and even develops. The key reason is the sanctions constantly imposed by Europe and the US against the Russian Federation and its allies, for example, Belarus, which especially fully supports our country in this difficult period. The number of already existing numerous sanctions imposed on both countries under study is constantly growing, which has already led to the destruction of many global value chains. Under these conditions, Russia and Belarus have no choice, they begin to create their own new global value chains among themselves. At the same time, cooperation with other countries is not being eliminated, many allies of Belarus and Russia, for example, China and India, only increase the number of ties between the countries. This situation creates in Belarus a desire to diversify its global value chains, which directly led to the formation of a diversification policy that implies a decrease in trade with the Russian Federation in favor of other states. Belarus needs to decide whether this redistribution is necessary, whether it will bring more benefits than negative aspects. The aim of the work is to identify new global value chains that have formed or may form between Russia and Belarus in the new geopolitical conditions. To do this, the following research objectives are set: (1) to identify global value chains that existed before the situation under study, that is, before the change in geopolitics; (2) to consider the actions that led to the creation of new global value chains, to study their consequences; (3) to study the impact of new global value chains on the human capital of Russia and Belarus. The following research methods are applied in the study: description, synthesis, generalization, statistical analysis, comparative analysis, induction, and deduction. The result of the syudy is the identification of new value chains that have been formed, liquidated, and become promising for Russia and Belarus. As a result of the study, a conclusion is made about the need to continue the economic integration of Russia and Belarus for the full implementation of all possible new global value chains. The author has found that the economic risks for Belarus with the full implementation of the diversification program are too great, despite the awareness of the reasons for the program’s occurrence. In the current situation, only the union of the two countries under study guarantees their development in the economic and social direction.
Innovative growth points of the region’s manufacturing industry
Authors:   Vologda Research Center of the Russian Academy of Sciences, Shirokova Elena Yu.
Published: June 2023

The withdrawal of foreign companies from the Russian market has led to the emergence of market niches that can be occupied by domestic manufacturers. Russia’s involvement in global value chains has led to a serious dependence on products from abroad and, as a result, to the degradation of a number of technological industries. With the strengthening of Western sanctions, the prompt replacement of goods that have ceased to be supplied to the country is a priority task for the executive authorities. The policy of import substitution, the implementation of which began in 2014, has been more successful in ensuring the national food security of the country, while high-tech industries are still critically dependent on imported equipment and technologies. Therefore, the identification of points of innovative growth in the regions allows us to identify manufacturing industries whose support will lead to leveling the negative consequences of the shortage of certain products in the domestic market. Until 2022, imports of technologically complex goods from the EU, the USA, and other countries included in the list of “unfriendly” occupied a significant share in the foreign trade of most regions. The regions of the Northwestern Federal District are industrially developed, and the problem of obsolescence of fixed assets was solved mainly through cooperation with foreign companies. Thus, the identification of promising industries capable of producing analogues of these goods is an urgent task for research. The aim of the study is to identify innovative points of growth of the manufacturing industry in the economy of the regions of the Northwestern Federal District of Russia. The article analyzes the structure of the economy of the regions in the District, their industry specialization, including the production of innovative products. The main methods of solving problems in the work are the use of the specialization coefficient for the average number of employees, the coefficient of specialization in the production of innovative products, and the coefficient of use of advanced production technologies. After comparing the indicators of specialization by the number of employees and the production of innovative products, the industries, whose activation can become a driver of the region’s economic growth in the near future, are identified. The region’s specialization in the production of innovative products determines the long-term prospects for its development for stable socio-economic development. In this regard, recommendations are developed for executive authorities to support certain types of economic activity, to activate the transition to the production of products with higher added value and to simplify the procedures for commercialization of the developed technologies. The results of the study are useful for the executive authorities of the region and scientists researching regional development problems.
Evolutionary approach to the formation of a typology of industrial associations
Authors:   Southern Federal University, Kaplyuk Ekaterina V. , Razvadovskaya Yulia V. ,   Southern Federal University
Published: June 2023

This article examines the formation in the Russian economy of industrial associations that act as the most important structural elements of the industrial sector at various stages of historical and economic development. Industrial associations today play an important role at all – micro-, meso-, macro- – levels of management. The aim of this article is to study the existing forms of industrial associations with a focus on the evolutionary component of their dynamics in the super-long-term period of the development of the domestic economy. The theoretical and methodological basis for the study of industrial associations is based on the convergence of the main provisions of the evolutionary approach and the historical method, the application of which ensured the isolation of the socio-economic genotype of industrial associations. In this context, the authors systematized the theoretical concepts, which made it possible to emphasize the multidimensional nature of the study of the parameters and patterns of the formation of the economic space. The authors infer that in the short and medium term the economic space is relatively stable, large-scale changes are observed in the long term; the importance of the institutional environment in the context of the evolution of the economic space is emphasized. The authors formulate the conclusion that the key genetic feature of industrial associations is the institution of ownership, which determines the viability and efficiency of various forms of cooperation at different levels of the economic system. Industrial associations demonstrate high efficiency, including due to the presence and strengthening of cooperative ties of participants based on the formation of the cycle “science – innovation – production.” The institution of cooperation in different time periods of economic development performed various functions, evolving in accordance with the historical context of the formation of the genotype. In the current socio-economic situation, industrial associations are able to stimulate the development of publicprivate partnership mechanisms, the emergence of new forms of business organization. The authors proposed a typology of industrial associations based on an evolutionary approach, which made it possible, on the basis of historical periodization, to single out four enlarged historical stages with the identification for each of them of a characteristic feature of the economic system, the evolutionary context of the formation of the genotype, the identification of the socio-economic genotype and types of industrial associations.
The border area population’s adaptation to modern challenges
Authors:   Kurgan Branch of the Institute of Economics of the Ural Branch of the Russian Academy of Sciences, Kremlev Nikolai D. , Orlov Sergey N. ,   Kurgan Branch of the Institute of Economics of the Ural Branch of the Russian Academy of Sciences
Published: June 2023

There are many approaches to assessing the level of adaptation of the population to modern challenges, but all of them are not perfect: they consider only certain aspects and factors of the problem. The aim of this article is to substantiate the tools for assessing the effectiveness of adaptation mechanisms of the border area of the public administration sector from the standpoint of a statistical approach. The authors attempt to determine the result of the adaptation of the population on the basis of criteria of the reproductive (adaptive) potential of the territory. They have developed criteria for evaluation from the position of: creating conditions for the accelerated adaptation of the population, the nature of the impact of the transformation process on the population, the effectiveness of adaptation mechanisms, people’s response to modern challenges, stresses and risks. The study uses the theory and methodology of official statistics, including the following methods: comparison, index, balance, grouping, and multivariate analysis. The tools for assessing the effectiveness of the mechanisms of the adaptation of the population are substantiated, the main factors influencing the speed of people’s habituation to changing living conditions are identified. The dynamics of the most important indicators characterizing the living conditions of the population and the reproductive potential of the territory according to 14 key quantitative and qualitative indicators for the period 2013–2020 is analyzed. During the period under review, the following should be attributed to positive results: the pandemic and sanctions do not have a significant impact on the lives of people and the activities of enterprises. The negative consequences include: a reduction in the birth rate and an increase in mortality; an increase in financial inequality; a decrease in the purchasing power of the population, etc. The authors onclude that the use of a statistical approach makes it possible to increase the reliability of information for an objective assessment of the degree of adaptation of the population of the border area to modern challenges based on the analysis of the level of the effectiveness of adaptation mechanisms and their impact on reproductive potential. Constant monitoring will show in the future the positive and negative factors affecting the living conditions of people and the speed of adaptation of the population of the country’s regions.
New Bis-1,3,4-Thiadiazoles Based on Fumaric Acid: Preparation, Structure Elucidation, Antibacterial Activities, and Quantum-Chemical Studies
Authors: Muğlu Halit , Yakan Hasan , Elefkhakry Ghaith Alabed Ibrayke , Altuner Ergin Murat , Çavuş M. Serdar
Published: June 2023

New bis-1,3,4-thiadiazoles 1–7 were obtained by the reaction of fumaric acid and N-(alkyl/aryl/cyclic)thiosemicarbazides in the presence of phosphorous oxychloride. The structures of all compounds were elucidated by FT-IR, 1H NMR, and 13C NMR and elemental analysis. Antibacterial activity of the compounds was studied for eight selected bacteria. Compounds 2–7 exhibited effect on Klebsiella pneumoniae. However, none of the compounds effect on Pseudomonas aeruginosa, Staphylococcus epidermidis, Salmonella enterica serovar Kentucky, Serratia marcescens. Self-consistent reaction force (SCRF) calculations were performed in DMSO medium to examine solvent energies using CPCM and SMD models. 6-31G(d) and 6-311++G(2d,2p) basis sets were used for DFT calculations. Besides electronic parameters such as electronegativity, electrophilicity and spectroscopic examinations of the compounds, QTAIM, local electron affinities, and Fukui analyses were also performed. Theoretical approaches supporting the experimental observations revealed that compounds containing aromatic and cyclic groups exhibit stronger antibacterial behavior than compounds containing aliphatic groups.
Potential Biochemical Properties of Endemic Onosma mutabilis
Authors: Eroglu Pelin , Civaner Mehmet Ulas , Calhan Selda Dogan , Ulger Mahmut , Binzet Riza
Published: June 2023

The Onosma L. (Lithospermae, Boraginaceae) genus contains many plant species with therapeutic properties due to its rich phytochemicals. Onosma mutabilis Boiss. & Hausskn. ex Boiss. (O. mutabilis) is the species for which there is not enough information on its characteristics. Objective: The total phenolic content, antioxidant activity, possible bioactive compounds, and antibacterial activities of ethanolic extracts of leaf, stem, root, and flower parts of endemic O. mutabilis were investigated. Conclusions: The total phenolic content of all O. mutabilis extracts was in the range of 9.2–31 mg gallic acid equivalent (GAE)/g of extract. According to the results of antioxidant activity, the IC50 antioxidant capacity values determined by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method were between 4.39–29 μg/mL, while the equivalent trolox antioxidant activity determined by the cupric reducing antioxidant values (CUPRAC) was 0.45–0.78 mmol of trolox equivalents (TE)/g of extract. Bioactive compounds have been analysed using gas chromatography coupled with mass spectrometry (GC/MS) and were found to contain 29 different chemical components. All plant extracts tested showed effective antibacterial activity against A. baumannii (ATCC 02026) (62.5 μg/mL MIC value) when compared to the reference drug Ampicillin (125 μg/mL).
Direct Determination of Kynurenic Acid with HPLC-MS/MS Method in Honey
Authors: Pavlin Anže , Pompe Matevž , Kočar Drago
Published: June 2023

Kynurenic acid (KYNA) has been attributed many beneficial properties, such as antioxidant, antiproliferative, anti-inflammatory, and anti-obesogenic, as it is believed to affect metabolism and weight gain. A rapid and simple HPLC-MS/MS method for the determination of kynurenic acid (KYNA) in honey has been developed. HPLC-MS/MS system allowed us to perform the analyzes without any special extraction or treatment of the samples. The study was carried out on different honeys: Chestnut (C), Linden (L), Acacia (A), Spruce (S), Silver Fir (SF), Forest (Fo) and Flower (F). The highest mean concentration, 682 μg/g, was determined for chestnut honey, making it one of the foods with the highest KYNA content.
Synthesis, Spectroscopic Characterization, Crystal Structures and Antibacterial Activity of Benzohydrazones Derived from 4-Pyridinecarboxaldehyde with Various Benzohydrazides
Authors: Zhou Yi-Xuan , Li Wei , You Zhonglu
Published: June 2023

Reaction of 4-pyridinecarboxaldehyde with 3-hydroxy-4-methoxybenzohydrazide, 4-bromobenzohydrazide and 4-dimethylaminobenzohydrazide, respectively in methanol afforded three new benzohydrazones. They are 3-hydroxy-4-methoxy-N’-(pyridin-4-ylmethylene)benzohydrazide (1), 4-bromo-N’-(pyridin-4-ylmethylene)benzohydrazide (2), and 4-(dimethylamino)-N’-(pyridin-4-ylmethylene)benzohydrazide (3). The compounds have been characterized by elemental analysis, 1H and 13C NMR and IR spectroscopy, as well as single crystal X-ray diffraction. The antibacterial activities of the compounds against E. coli, P. aeruginosa, B. subtilis, and S. aureus were investigated and gave interesting results.
Copying Archived LTEE Samples v1
Authors: D Blount Zachary
Published: June 2023

This protocol describes how to replenish the frozen "fossil" record of the E. coli Long-Term Evolution Experiment (LTEE) by making copies of freezer stocks. Different methods are used to copy population samples versus clonal samples. For the former, the goal is to make a representative copy that maintains the genetic diversity that is present in the population. For the latter, the goal is to make a copy of a homogeneous cell population without allowing it to evolve new mutations. The culture media and supplies needed for this protocol are described here:
Türkiye’deki bazı Sapsız meşe (Quercus petraea (Mattuschka) Liebl.) tohum meşcerelerinin genel değerlendirilmesi
Authors: MEŞE Özlem , ÖNER M. Nuri , AYAN Sezgin
Published: June 2023

Meşe türlerinden biri olan sapsız meşe, Quercus petraea subsp. petraea, Quercus petraea subsp. iberica ve Quercus petraea subsp. pinnatiloba olmak üzere üç alt tür ile temsil edilmektedir. Bunlardan subsp. petraea, Bolu ve Kırklareli’deki 200 m yükseltilerde; subsp. iberica, İstanbul, Kastamonu, Artvin, Balıkesir, Bursa, Eskişehir, Kırklareli, Kütahya, Sakarya, Sinop, Tokat, Trabzon’daki 0-1600 m yükseltilerde; subsp. pinnatiloba ise Adana, Hakkâri, Bingöl, Elazığ, Hatay, İçel, Malatya, Kahramanmaraş, Muş, Tunceli, Van yörelerindeki 1200-2200 m yükseltilerde doğal yayılış göstermektedir. Türkiye’de sapsız meşe için Orman Genel Müdürülüğü (OGM) adına Orman Ağaçları Tohum Islah Araştırma Enstitüsünce dokuz adet tohum meşceresi tescil edilip Ulusal Kayıt (UK) numarası alınmış ve beşi sonra iptal edilmiştir. Halen tohum meşceresi vasfını taşıyan dördü; Elazığ-Tunceli-Nazımiye (UK no:289), İstanbul-Demirköy-Karacadağ (UK no:294), Bursa-Mustafakemalpaşa-Gürgendağı (UK no:326) ve Bolu-Mengen-Kaynarca (UK no:400)’dır. Bu çalışmada hem tohum meşceresi vasfını taşıyan ıslah tesislerinin özellikleri ve seçim kriterleri (ölçütleri) değerlendirilmiş hem de listeden çıkarılan beş tohum meşceresinin (Elazığ-Bingöl-Ilıca (UK no:290), Sakarya-Akyazı-Keremali (UK no:300), Bolu-Bolu-Ayıkaya (UK no:301), Bolu-Mudurnu-Sarıkaya (UK no:302) ve Zonguldak-Dirgine-Aksu (UK no: 297)) iptal gerekçesi ve özellikleri irdelenmiştir.
Youth in Zurich’s Public Spaces: Hanging Out as an In/Exclusive Way of Taking Place in the City
Authors: Colombo Annamaria , Balleys Claire , Tadorian Marc , Colella Marianna
Published: June 2023

Based on the preliminary results of an ongoing research project focused on the social and cultural practices of young people in physical and virtual public spaces across four urban areas in Switzerland, this article explores the everyday spatial behavior of youth who hang out in Zurich’s public spaces. It highlights how everyday activities provide these young people with a means of coming to terms with the inclusive and exclusive potential of the urban public spaces they appropriate and how, in turn, they adopt spatial practices that can prove more or less inclusive. Some of these practices may be provocative or even subversive; and whereas others are more discreet (sometimes involving unconscious behavior or passing unnoticed), we argue that they are no less political. The subtle ways in which young people progressively take their place in the city could best be described as “micropolitical.”
Development of Scientific Support of Water Reclamation on Irrigated Lands of Ukraine: Historiography of the Period of Independence
Authors:   Institute of Water Problems and Land Reclamation of National Academy of Agrarian Sciences of Ukraine, Yehorova Svitlana
Published: June 2023

It was established that during the period of Ukraine’s independence, historiography began to play the role of an integration factor, maintaining the appropriate level of scientific knowledge, preserving and supplementing the methodological apparatus of modern historical science. It has been found that in recent decades, a number of meaningful scientific works have been published, which contain systematized factual material on the development of scientific support for water reclamation on irrigated lands of Ukraine, a thorough analysis of scientific technologies and their theoretical generalizations. It was determined that the historical works of the period of Ukraine’s independence are characterized by the multi-facetedness and content of generalizations, the objectivity of approaches to the study of the evolution of the scientific-organizational foundations of the use of water resources for land irrigation. Historical works highlight the evolution of certain scientific directions, theories, concepts and technologies regarding the improvement of water reclamation in agrarian production on irrigated lands; development of scientific foundations of effective management of water resources for agricultural land reclamation; the contribution of higher education institutions, and scientific-research institutions and research teams to the development of scientific technologies for the conservation and balanced use of water resources in irrigated farming; the evolution of the working and practical implementation of water reclamation on irrigated lands in the context of the activities of well-known agrarian scientists of Ukraine. It was established that at the beginning of the 21st century, thanks to the cooperation of Ukrainian and foreign scientists, the working and implementation of innovative technologies for the ecologically safe use of water and land resources gained significant development and has great prospects, especially in conditions of climate change. An own position has been formed regarding the choice of the most accurate and scientifically based reflection of the historical development of scientific support for water reclamation on irrigated lands of Ukraine, which is updated in the conditions of global challenges and threats today.
REVIEW OF THE MONOGRAPH BY V. I. KUCHER «Scientific and organizational support of animal husbandry in Ukraine during the Second World War. Kyiv: Science capital, 2022. 224 p.
Authors:   Institute of the History of Agrarian Science, Education and Techniques of NSAL of NAAS, Shchebetiuk Nataliia
Published: June 2023

The monograph of Doctor of Historical Sciences, Professor Volodymyr Kucher, dedicated to the coverage of events and phenomena in the development of the livestock industry in Ukraine on the eve and during the Second World War, was reviewed. In the scientific publication, based on the analysis of available archival and printed sources, reports of scientific research institutions, the experience of animal husbandry practitioners who were direct participants in the events, their contribution to the preservation and reproduction of breeding stock of agricultural animals of various species in the difficult conditions of war and the post-war period. It is argued that methodological and scientific and organizational conditions for the development of the livestock industry in Ukraine were laid in the post-war years. The peer-reviewed work is one of the few modern publications that reflect the historical development of agricultural science in crisis conditions, in particular, the provision of scientific support for domestic animal husbandry.
ZENON FISZ’S AUSTROPHOBIA
Authors:   University of Białystok, Ławski Jarosław
Published: June 2023

The author of the article analyzes the account of the Polish prose writer Zenon Leonard Fisz (1820–1870) on a journey by steamboat from Odessa to Pest and then by rail to Vienna. Fisz is sensitive to the image of the wild civilization of the Balkans, admiring nature and the Danube from the ship. On the border of Austria, his Austrophobia is revealed. Austria and then Vienna, he identifies the Viennese with Germany, whose grotesque description is contained in Letters from a journey (Vilnius 1858, vol. 1-3). The identification of Austrian and German culture in Fisz is complete, ostentatious and charged with idiosyncrasy. Fisz’s austrophobia develops on a cultural and civilizational basis. The writer is afraid of the negative consequences of taking over elements of Western civilization by the European, Slavic East.
Mental State Prediction Using Machine Learning and EEG Signal
Authors: Datar Dinesh , Khobragade R N
Published: June 2023

One of the most exciting areas of computer science right now is brain-computer interface (BCI) research. A conduit for data flow between both the brain as well as an electronic device is the brain-computer interface (BCI). Researchers in several disciplines have benefited from the advancements made possible by brain-computer interfaces. Primary fields of study include healthcare and neuroergonomics. Brain signals could be used in a variety of ways to improve healthcare at every stage, from diagnosis to rehabilitation to eventual restoration. In this research, we demonstrate how to classify EEG signals of brain waves using machine learning algorithms for predicting mental health states. The XGBoost algorithm's results have an accuracy of 99.62%, which is higher than that of any other study of its kind and the best result to date for diagnosing people's mental states from their EEG signals. This discovery will aid in taking efforts [1] to predict mental state using EEG signals to the next level.
Performance Analysis of Different Optimization Algorithms for Multi-Class Object Detection
Authors: Borade Jay Laxman , Muddana Akkalakshmi
Published: June 2023

Object recognition is a significant approach employed for recognizing suitable objects from the image. Various improvements, particularly in computer vision, are probable to diagnose highly difficult tasks with the assistance of local feature detection methodologies. Detecting multi-class objects is quite challenging, and many existing researches have worked to enhance the overall accuracy. But because of certain limitations like higher network loss, degraded training ability, improper consideration of features, less convergent and so on. The proposed research introduced a hybrid convolutional neural network (H-CNN) approach to overcome these drawbacks. The collected input images are pre-processed initially through Gaussian filtering to eradicate the noise and enhance the image quality. Followed by image pre-processing, the objects present in the images are localized using Grid Guided Localization (GGL). The effective features are extracted from the localized objects using the AlexNet model. Different objects are classified by replacing the concluding softmax layer of AlexNet with Support Vector Regression (SVR) model. The losses present in the network model are optimized using the Improved Grey Wolf (IGW) optimization procedure. The performances of the proposed model are analyzed using PYTHON. Various datasets are employed, including MIT-67, PASCAL VOC2010, Microsoft (MS)-COCO and MSRC. The performances are analyzed by varying the loss optimization algorithms like improved Particle Swarm Optimization (IPSO), improved Genetic Algorithm (IGA), and improved dragon fly algorithm (IDFA), improved simulated annealing algorithm (ISAA) and improved bacterial foraging algorithm (IBFA), to choose the best algorithm. The proposed accuracy outcomes are attained as PASCAL VOC2010 (95.04%), MIT-67 dataset (96.02%), MSRC (97.37%), and MS COCO (94.53%), respectively.
Detection of Pulmonary Embolism: Workflow Architecture and Comparative Analysis of the CNN Models
Authors: Tawte Akhilesh , Gonge Sudhanshu , Joshi Rahul , Mulay Preeti , Vora Deepali , Kotecha Ketan
Published: June 2023

Machine learning has proven to be a practical medical image processing technique for pattern discovery in low-quality labelled and unlabeled datasets. Deep vein thrombosis and pulmonary embolism are both examples of venous thromboembolism, which is a key factor in patient mortality and necessitates prompt diagnosis by experts. An immediate diagnosis and course of treatment are necessary for the life-threatening cardiovascular condition known as pulmonary embolism (PE). In the study of medical imaging, especially the identification of PE, machine learning (ML) algorithms have produced encouraging results. This study's objective is to assess how well machine learning (ML) algorithms perform in identifying PE in computed tomography (CT) scans. A range of ML approaches were used to the dataset, including deep learning algorithms such as convolutional neural networks. The effectiveness of PE detection systems can be greatly enhanced by the use of cutting-edge methodologies like deep learning, which lowers the possibility of incorrect diagnoses and enables the quick administration of therapy to individuals who require it. This work contributes to the growing body of evidence that supports the use of ML in medical imaging and diagnosis. Future research should examine how these algorithms might be included into clinical workflows, resolving any potential implementation challenges, and making sure their adoption is done so in a secure and efficient way. In this study, we provide a thorough evaluation of three different models: the streamlined architecture MobileNetV2 with an accuracy of 96%, compared to other models like the Xception model with an accuracy of 91%, and the Efficientnet B5 model with an accuracy of 97%, after observation and process following.
VALUES OF EDUCATION IN EUROPE AFTER WORLD WAR I IN NEWLY CREATED COUNTRIES – EXAMPLE OF LATVIA
Authors: Jurs Pavels , Pelnēna Ivita
Published: June 2023

The First World War (1914 - 1918) strengthened the idea of self-determination of nations in Europe, while the end of the war created favourable conditions for the creation of new states, including the proclamation of the Republic of Latvia on November 18, 1918. The creation of an independent Latvia State for the first time gave an opportunity to create an education system based on national interests. As a result, the Latvia education system during the period from 1919 to 1934 was transformed according to socioeconomic and political changes, creating for the first time a national education system based on the innovative pedagogical ideas of the given era. Basically, during the period of Latvia's first free state, in the democratic regime, the education system, in compliance with trends in Europe, was dominated by reform pedagogy. The purpose of the article is, based on the content analysis of periodicals and historical sources, to identify the existing values of Latvia education (school pedagogy) during the democratic period from 1919 to 1934, in the context of European educational values. As a result of the theoretical research, based on the content analysis of periodicals and historical sources, the following educational values have been identified as the most important: creativity; discipline; obedience of students; kindness; humility; individualization; personality of the teacher; professional mastery of the teacher; love of the fatherland.
Keratosis peripapillary Otto–Moncorps
Authors: Snarskaya Elena S. , Shnakhova Lidiya M. , Vasileva Diana A.
Published: June 2023

OttoMoncorps keratosis is a rare dermatosis, which is excessive keratinization of the nipple and areola of the mammary gland with an unknown etiology and pathogenesis. According to the classification proposed by LevyFrankel in 1938, the disease can be represented by three types: type 1 ― a variant of the epidermal nevus, type 2 ― associated with other diseases and type 3 ― idiopathic. The diagnosis is based on the data of the clinical picture, represented by diffuse keratinization of the nipple and areola of the mammary gland, dark brown in color, resembling basalt cubes. To date, there are no effective pathogenetic methods of treatment, methods of regular topical therapy are recommended (topical steroids and retinoids, keratolytics in high concentrations, emollients and moisturizers), as well as surgical methods of treatment (excision of hyperkeratotic overlays with a carbon dioxide laser, radiosurgical methods).
The article presents a unique case of hyperkeratosis of the periarticular circle and breast nipple type 3 according to LevyFrankel in a 39-year-old patient. The diagnosis was made on the basis of anamnesis data (onset of the disease at puberty), a typical clinical picture (bilateral lesion; dermatosis in the form of hyperkeratotic layers resembling basalt cubes), as well as the characteristic course of the disease (relapse after discontinuation of therapy with local remedies). The interest of the presented clinical case lies not only in the rarity of this dermatosis and the duration of the disease history (for 24 years), but also in the presence of an extra-mammary lesion and a possible association with infertility of the patient.
Dynamics of changes in tumor-associated macrophages in patients with primary skin melanoma depending on the method of surgical treatment
Authors: Yargunin S.  A. , Reshetov I.  V. , Shoikhet Ya.  N. , Pyatakov S.  N.
Published: June 2023

Summary: Skin melanoma is one of the deadliest among human skin tumors, and surgery remains the first and main method in its combined treatment. Despite the seemingly radical nature of surgical interventions in patients with primary skin melanoma, the frequency of locoregional recurrence and metastasis remains high. The question of the impact of surgical treatment on the evolution of the melanoma microenvironment remains unclear.

Aim: to investigate the dynamics of polarization in tumor-associated macrophages in patients with primary skin melanoma of stage 0-IIa and in subsequent metastatic lesions to assess the impact of postoperative ischemia on survival of patients.

Results: it was found that in patients with primary skin melanoma of stage 0-IIa plastic replacement of a tissue defect, compared with conventional suturing, can lead to a decrease in the density in the intrastromal distribution of pro-inflammatory CD68 + macrophages in the surgical focus, as well as less frequent polarization of TAM cells in the M2 direction and migration to the intrastromal component of the tumor, their more frequent mixed content, which, as a result, affects the survival of this category of patients for the better.

Conclusions: plastic closing a surgical defect in patients with primary skin melanoma of stage 0-IIa may affect the duration of postoperative ischemia and the polarization of TAM cells. Plastic replacement of a tissue defect after tumor removal improves five-year survival rates (PFS by 22,6 % (p = 0.003) and OS by 13,1% (p = 0.029).
Tanggungjawab Notaris Terhadap Sengketa Para Pihak Terkait Akta Perjanjian Utang Berdasarkan Keterangan Palsu
Authors: Nugrahani Linda , Sudarwanto Albertus Sentot , Mulyanto Mulyanto
Published: June 2023

There are still many authentic deeds made by Notaries containing false satatements. This often causes problems and losses for one of the parties to the deed. This research is doctrinal legal research using primary and secondary legal materials hereinafter through statute and copcetional approach. The result showthat the factors behind the making of an authentic deed that containing false statements are the intentions of the appearers themselves or the Notary’s negligence towards the precautionary principle in making the deed. Regarding the false statements submitted by the appearers, the Notary cannot be held responsible for the loaaes incurred. It is entirely the responsibility of the appearer. Meanwhile, a Notary who knows informations that submitted by the appearer is fake for making the deed, then the Notary can be responsible both civilly, administratively, and criminally.

Keywords : responsibility; Notary; authentic deed.
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Authors: PLS Admin
Published: June 2023

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Histopathological correlation in oral biopsies in clinically diagnosed pediatric oral lesions: A 12-year institutional archival study
Authors: Shafi Shugufta , Gupta Rakesh K , Anjum Rubeena , Kaur Mandeep
Published: June 2023

: The present study was aimed to determine the histopathological correlation in lesions of oral cavity in children aged 14 years and below received for diagnosis in the Oral Pathology Department of the Indira Gandhi Government Dental College Jammu, J&K.

: The archives of the Department of Oral Pathology and Microbiology were retrospectively analyzed. Biopsy records of all oral lesions from pediatric patients, aged 0–14 years, from Department Of Oral and Maxillofacial Pathology & Oral Microbiology, Indira Gandhi Government Dental College Jammu, J&K, from 2011 to 2022 were considered. Descriptive statistical analysis and using computer software Pearson’s Chi‑square test was performed.

: 36 biopsies (4.9%) belonged to pediatric population out of the total 727 biopsies that were received during the period. Females (64%) showed greater prevalence compared to males (36%). Affected age group seen were between10–14 years. The most common category of lesions diagnosed were cysts and the odontogenic tumors were the least seen. Mandible showed more predilection compared to maxilla in jaws which was most common location involved, followed by the gingiva, palate, lower lip and labial mucosa. On comparing the histopathological diagnosis, dentigerous cysts (22%) were the most common followed by radicular cysts (17%), fibrous hyperplasia (14%), pyogenic granuloma (11%), central giant cell granuloma (8%), hyperplasia of minor salivary glands (5.6%) and percentage of aneurysmal bone cyst, peripheral giant cell granuloma, peripheral ossifying fibroma, central ossifying fibroma, juvenile ossifying fibroma, cementoblastoma, ameloblastoma and necrotic bone all was equal (2.8%). A statistically significant association of age and gender was seen with the category of the lesion.

:The lesions were more common in the mandible with a female predilection and in age group >10 years. The majority of oral and maxillofacial lesions detected in pediatric population were benign similar to the previous reports.
Spectrum of Colorectal Adenocarcinomas: A 4 year experience in a tertiary care centre from Western Maharashtra
Authors: Lakhe Rachana , Patil Amrutraj , Doshi Rajeev , Doshi Preeti , Kesarkhane Milind , Nimbargi Ravindra
Published: June 2023

Colorectal cancer is the third most common cancer in both men and women. Environmental and genetic factors play a role in the development of colorectal carcinomaThe majority of colorectal cancers are sporadic, with hereditary cancer syndrome accounting for 10% of cases. Precursor lesions like adenoma that transform into adenocarcinoma cause the majority of colorectal cancers.

: A total of 72 of colorectal malignancies were studied for histopathological features. The histologic features were studied for site, grade, tumor -infiltrating lymphocytes, Crohn -like lymphocytic reaction, mucinous histology, signet ring cell histology, and medullary growth pattern.

: The mean age of the patients was 59.52 ± 11.80 years with M:F 1.76:1. Light microscopy showed TILs in 16 (22.2%) patients, followed by mucinous areas in 5 (6.9%), crohn like lymphocytic reaction in 4 (5.6%) and signet ring morphology in 2 (2.8%) patients.

This study concludes that colorectal carcinomas are more common in 5th and 6th decade of life with slight male preponderance. The most common malignant lesion being moderately differentiated adenocarcinomas. This study highlights age and gender prevalence, as well as histopathological characteristics of colorectal carcinomas in this demographic region .
Conversations about complex issues
Authors: Trask Suzanne , D'Souza Erica , Swinburn Boyd , Bay Jacquie
Published: June 2023

How do we support learning and teaching about complex issues? Researchers from the University of Auckland worked with 54 students and teachers from three Auckland secondary schools to evaluate health-science learning designed to investigate this question. The instructional strategies based on context familiarity, systems thinking, and narrative pedagogies can be adapted to support learning about other contexts involving complex issues.
К вопросу о дифференцированном понимании омонимичных грамматических явлений в процессе чтения
Authors: Гончарова А.В.
Published: June 2023

Статья посвящена анализу омонимичных грамматических конструкций с суффиксом –ing-. Проводится детальное рассмотрение данных физиологии и психологии, имеющих непосредственное отношение к восприятию и разграничению омонимичных форм. Проведенное исследование грамматического материала позволило автору создать набор дифференцирующих схем-упражнений для использования на занятиях по английскому языку, которые позволяют легко понять и усвоить различия между омонимичными конструкциями с суффиксом – ing-.
Сравнительная характеристика способов заготовки мускусной железы бобра речного
Authors: Вечтомова Е.А., , Орлова М.М.
Published: June 2023

В работе приведена информация по способам заготовки и первичной переработки мускусной железы на примере бобра речного. Показано влияние половозрастных характеристик на органолептические показатели качества железы. Приведена информация по двум способам заготовки – воздушно-сухому и холодному, отличающимся температурным режимом, продолжительностью и качеством получаемого продукта. Приведены данные по изготовлению водно-спиртовых экстрактов из мускуса и их применении в профилактике и лечении различных заболеваний.
Стратегии использования информационных технологий для улучшения преподавания и обучения
Authors: Абдулкадыров У.У , Исаева М.З , Акавова А.И
Published: June 2023

В этой статье рассматриваются стратегии использования информационных технологий для улучшения преподавания и обучения. В нем рассматривается, как можно использовать технологии для повышения вовлеченности учащихся, изменения динамики в классе и создания более значимого учебного опыта. В статье представлен обзор современного состояния образовательных технологий, а также лучшие практики внедрения технологических решений в учебные планы. Наконец, в нем обсуждаются потенциальные преимущества использования информационных технологий в классе.
Онлайн курс «Эвенкийский язык для начинающих» как средство популяризации и сохранения национального языка
Authors: Антипина М.Д.
Published: June 2023

Согласно статистическим данным, уровень владения родным языком у коренного населения неуклонно снижается. Если в 1997 году эвенков, свободно говорящих на родном языке, было около 30%, то в 2018 году – уже чуть больше 15%. По мнению исследователей к настоящему времени число носителей родного языка среди эвенков России не превышает 6-8%. В целях пропаганды и сохранения эвенкийского языка нами разработан онлайн курс по изучению эвенкийского языка для начинающих
Воспитание любви к Родине у младших школьников при проведении викторины «Любовь к Родине – любовь к родному языку»
Authors: Антохина В.А., , Будаева М.А., , Хрущева Е.А.
Published: June 2023

Статья посвящена одной из актуальных проблем современного начального образования – поиску методических путей решения проблемы воспитания у младших школьников любви к Родине и к родному языку как неотъемлемой составляющей чувства патриотизма. В статье рассматриваются возможности викторины как эффективной формы организации деятельности обучающихся в процессе воспитания у них любви к родному языку и к Отечеству. Для обсуждения предлагается сценарий викторины «Любовь к Родине – любовь к родному языку», апробированной авторами в работе с учащимися третьих классов в рамках внеурочной деятельности
Разработка сценариев настольно-ролевой игры D&D для внеурочных занятий по русскому языку в начальной школе
Authors: Антохина В.А., , Ретюнская А.К.
Published: June 2023

В данной статье рассматриваются возможности разработки сценариев настольноролевой игры D&D. Представлена для обсуждения методика написания сценариев, учитывающая особенности названной игры, требования к формированию предметных, метапредметных результатов начального обучения русскому языку, интересы детей младшего школьного возраста.
Педагогические условия формирования экологической культуры студентов в учреждениях среднего профессионального образования
Authors: Бабин В.Н , Ким А.С.
Published: June 2023

В статье исследуются вопросы создания педагогических условий формирования экологической культуры студентов. Обзор основан на анализе учреждений среднего профессионального образования. Рассматривается необходимость решения экологических проблем в России и мире в настоящее время. Изучаются особенности современного образовательного пространства, а так же возможности повышения качества экологической культуры учащихся в системе образования. Рассматривается необходимость комплексного подхода к созданию педагогических условий для формирования экологической культуры в образовательном учреждении.
К вопросу о модернизации системы высшего образования
Authors: Беличенко О.М , Сомова М.Н.
Published: June 2023

Рассматривается история возникновения и развития Болонского процесса, приводятся организационно-правовые принципы Болонского процесса в России. Описываются особенности использования специалитета, бакалавриата и магистратуры в системе высшего образования сегодня. Обосновывается необходимость модернизации высшего образования, предлагаются некоторые пути развития
Влияние допинга на спортсменов в возрасте 18-25 лет
Authors: Гусев П.М. , , Юсупова Р.М.
Published: June 2023

Данная статья рассматривает вопрос о том, как допинг наносит тяжелый урон молодым спортсменам в возрасте от 18 до 25 лет. В статье рассматривается многогранный вред допинга для здоровья и психологической стабильности спортсменов, а также возможные последствия использования запрещенных средств, включая дисквалификацию и угрозу карьеры. Автор подчеркивает важность честного и упорного труда в достижении спортивных целей и призывает молодых спортсменов следовать принципам чистого спорта
Преимущества и недостатки системы дистанционного обучения
Authors: Ескендиров К.Б., , Ермекова Н.С., , Ескендирова Д.Ж.
Published: June 2023

В статье рассмотрены процессы технического обеспечения при создании системы дистанционного обучения, преимущества и недостатки системы дистанционного обучения.
Investigating elements influencing cultural communication behavior of kindergarten students from ethnic minorities in Vietnam's educational system
Authors: Nguyen Sau Thi Ut , Hua Thoa Thi Kim
Published: June 2023

The development of communication skills is crucial, particularly for directing the cultural communication practices of kindergarten students and ethnic minority students. The goal of the study was to examine the reality of children's engagement in cultural communication behavior and the reality of the elements that influenced the educational process of cultural communication behavior. There were 130 participants, including 30 administrators and 100 kindergarten teachers from ethnic minorities. The study found out that students were engaged in intercultural activities at an average rate and less frequently. In addition, it was evident that elements such as focus, the direction of management, and the expertise of educators had the biggest influence on the educational process. The study recommends that educators implement a policy of fair support for teachers and students, provide instructors with capacity-building training, and collaborate closely with students' families to increase the learning quality of student work. For kindergarteners to learn how to act in a way that is culturally communicative they need a lot of attention and direction from all levels on how to make policies that will improve the skills of both teachers and students. This is because the goal of education is to help children develop behaviors that are culturally communicative. At the same time, teachers work with the kids' families to teach them about cultural communication patterns in the best way possible.