bluuebunny/crossref_metadata_2025 huggingface dataset:
Ideologeme in Political Communication: Interpersonal Aspect
Authors: Ivanov Petr , Katyshev Pavel
Published: June 2023

The ideologeme is responsible for the category of interpersonality in the political discourse. The authors studied ideologemes in blogs published on the Yandex.Zen platform to identify their role in the discursive modeling of the social and personal opinions of the blogger, the recipient, and the political referents. The category of interpersonality revealed two models associated with the transformation of meaning. The first group was connected with recontextualization and included mocking, comparison, and referent replacement. The second group transformed the form and structure of the intentional component of the meaning by adding or replacing an element, as well as by demetaphorizing or secondary metaphorization.
Social Networks and the Regulatory Function of Language: Internet Debates on Virtual Verbal Intelligence
Authors: Lebedeva Natal'ya
Published: June 2023

The article describes the regulatory function of the language of Internet communication. The research featured the Internet discussion triggered by Olga Yurochkina's blog called The Little Things of Life. The users expressed their attitude to the spelling and punctuation violations that are typical of online communication. According to the hypothesis, special (philological) knowledge is opposed to the vernacular one. Consequently, educated users demand stricter control of conventional language rules. The author used comparative approach to develop a typology of opinions. The Internet discussion differed from similar offline debates in its causes, patterns, and results. The regulatory function was never mentioned directly but could be deciphered from the way the users formulated their question and the latent content of the statements they made.
Digitization of Socio-Political Interaction: Mobilization of Real and Virtual Communication
Authors: Nyatina Natal'ya , Grigorik Nikita , Molchanov Artem
Published: June 2023

Digital communication allows almost every subject of social and political interaction to act as a communicator, interpreter, and broadcaster of information. Online users can also act as petitioners, appealing to the authorities, other citizens, opinion leaders, experts, etc. Government representatives are interpreters and administrators of political decisions. Digital communication gives them an opportunity to demonstrate their social positions, citizenship, solidarity, and attitudes. And this is where the following contradiction arrives. On the one hand, the authorities need to mobilize real and virtual communication. On the other hand, they perceive mobilized population as a threat: to be controlled, organized social communities require resources, as well as complex and expensive measures. The authors reviewed publications that featured socio-political interaction. The review revealed that the mobilization of civic participation remains understudied. Digitalization increases the importance and relevance of network practices of social activism. Traditional forms of interaction between community members and authorities are gradually being replaced by networked, flexible, and participatory ones. Constructive and destructive forms of mobilization transform socio-political relations. The review provided a diversification of constructive and destructive practices of public participation in decision-making at federal, regional, local, and company levels. Digital forms and methods of socio-political interaction increase in number, and theri measurement indicators keep changing.
Perception of Virtual Reality by Senior vs. Junior Russian Cinema Audience: A Case Study of Cheburashka
Authors: Bresler Mihail , Yunusov Daniil
Published: June 2023

Virtual reality is integral to digital society, where members interact both in real and virtual environment. Cinematography triggers virtual communication between film viewers of all ages. This phenomenon finds expression in the distribution and transformation of information in social networks. This research featured the film Cheburashka (2023) and its virtual environment as a critical success factor. The authors used the information-communication method in its rhizome paradigm to study the virtual communication created by cinematographic means. In Postmodernism, the rhizome is a network of film episodes, quotes, and allusions. This network of interconnected references forms the virtual reality of the film. The empirical study involved a content analysis of internet comments and reviews made by middle age adults (45+) and a qualitative focus group study of young people aged 18–24. Different generations perceived the film differently. The so-called digital generation could perceive the virtual reality of the film, while the senior generation saw the movie as nothing but a full-length version of the animated film of their childhood. The middle age adults were responsible for more than a third of all the critical comments. The appeal to nostalgia failed as a cinematographic device while the ability to perceive the virtual reality turned out to be an important factor of virtual communication with the mass viewer. The research results develop the theory target audience.
China’s Media Image in the Russian Social Networks Based on Posts and Comments about Chinese Popular Music
Authors: Nesterova Natalia , Sabaeva Yuliya
Published: June 2023

The article reconstructs the media image of China based on social network discussions about Chinese pop music. As a new medium, social networks reflect the mutual socio-cultural interest of Russia and China. The author describes the concept of national media image in media linguistics and intercultural communication using China News. EKD, a public page in the VKontakte social network. The methods of media linguistics, cultural linguistics, axiology, and linguistic analysis helped to reveal the main themes in the image of China: musical genres; musicians and singers, their popularity in China and abroad; authors' opinions; commentators' opinions; non-verbal means. The research also revealed linguistic and non-linguistic means that establish Chinese pop music as part of the musical and performing arts. China appears as a country with a well-developed modern musical and performing culture, popular both in China and abroad.
Conflict of Text Interpretations as a Consequence of Cognitive Dissonance in Internet Disputes
Authors: Kim Lidiya
Published: June 2023

Latent cognitive dissonance in Internet disputers manifests itself as a conflict of text interpretations. This cognitive interpretation process of pre-textual cognitive dissonance often results in aggressive comments. The author analyzed interpretive Internet texts (comments) to reveal the cognitive patterns and prove the effect of pre-textual, i.e., cognitive, dissonance on the language and content of Internet comments. Addressee's external interpretive activity, represented in the text, is determined by internal cognitive processes, i.e., pre-textual presumptions and expectations. The study was based on the article entitled The people are multiplying "on earth", which was posted on a Runet information network resource on January 30, 2023. The article, which featured national demographic problems and possible solutions, yielded 189 comments that clearly illustrated the mechanism of conflict of interpretations. The methods of content and intent analyses revealed two cognitive patterns: the first one correlated with the intentional content of the trigger-text whereas the second pattern did not. Both patterns covered a number of cognitive models. The original text, subjectively interpreted by the addressee, triggered a wide range of comments that followed various cognitive patterns. As a result, the discussion unfolded as a conflict scenario, i.e., a struggle of attitudes and opinions, determined by the pre-textual cognitive dissonance of the disputers.
Digital Mobilization of Social and Political Interaction in Network Communities: Regional Specifics
Authors: Golovatsky Evgeny
Published: June 2023

The digital mobilization of regional social and political interactions remains a relevant research topic. It provides obvious research innovations, new digital research algorithms, and non-trivial solutions, as well as an effective n-code measurement tool. Digital freedom means availability of network tools and services, where ordinary users can be actors of digital mobilization. In order to visualize an experimental scenario, the authors converted original data in the PolyAnalyst program to obtain thematic groups and an actor-network model for online communities of Kuzbass and the Tyumen Region. The generated dataset made it possible to consider common and different discussion topics, which were grouped by acute issues: crime, law, the military operation in Ukraine, infrastructure, etc. The study revealed some methods of user search and processing of chatbot requests. The digital tools demonstrated the regional features of the choice of online media, local resources, and topics. Online discussions give rise to new communication practices, i.e., the ability to receive, discuss, and shape relevant thematic agendas in real time, sometimes ahead of government officials and official media. This phenomenon can be explained by the availability of online community, hybrid communication technologies, repeated discussions, and alternative reliable sources.
Network Discourse of Western and Eastern Philosophy
Authors: Bresler Mihail , Demichev Il'ya
Published: June 2023

In the XXI century, network communication generates its own philosophical discourse of thinking. However, network discourse and network interaction appeared at the dawn of axial time, first, in the Eastern philosophy and, eventually, in the Western one. The authors used the information and communication approach, as well as the historical method, to trace the network discourse from traditional Chinese philosophy all the way through Leibnizianism and classical German philosophy. The research also covered the manifestations of triadic network thinking in the Western philosophy of the XX century, including the Russian philosophy of the new and modern history. It featured the Taoist and Confucian categories of trace, void, and dynamic stability, which were rediscovered by Postmodernism. When the network discourse took over the linear one, it opened up prospects for new, digital thinking. The obtained data develop the ontological aspects of network existence and facilitate the applied studies of network communications.
Generation Z and Chinese Neterature
Authors: Galiullina Svetlana , Popod'ko Ekaterina , Popod'ko Anastasiya
Published: June 2023

The article describes the generation of centennials aka Generation Z and their role in literary creativity. Digital technologies have a great impact on their reading habits. The research featured the phenomenon of neterature, or network literature, and the role of Chinese centennials in it. The authors defined the concept of generation Z and compared traditional literature with online literature. They used such sites as Yi En Consulting and Qidian to give a brief history of Chinese neterature, which they divided into three main periods. Centennials rely on random choice and prefer contemporary literature, mainly fantasy, chronofantasy, and romance. Centennial online authors and readers are of approximately the same age and share the same values, upbringing, literary preferences, and interests, which makes it easier for the writers to meet the market needs. Online literature is not an alternative to traditional literature, but rather its next evolution stage. Currently, it is the most dynamic part of literature, and its influence on the young generation can hardly be overestimated.
Degradation of tetracycline by activated peroxodisulfate using a sulfur-modified iron-based material
Authors: Gao Shanxue , Zhang Nan , Chen Lei
Published: June 2023

The activation of persulfate by an iron-based catalyst presents a promising approach for the degradation of antibiotics; however, the activation efficiency remains a challenge. Herein, a sulfur-modified iron-based catalyst (S–Fe) by co-precipitation of sodium thiosulfate and ferrous sulfate in a molar ratio of 1:2 was prepared and the efficacy of the S–Fe/PDS system for the removal of tetracycline (TCH) was studied, where a higher removal efficiency was observed compared to the Fe/PDS system. Moreover, the effects of TCH concentration, PDS concentration, initial pH, and catalyst dosage on TCH removal were evaluated, and the highest efficiency was about 92.6% within a 30 min reaction time using a catalyst dosage of 1.0 g/L, a PDS dosage of 2.0 g/L, and a solution pH value of 7. The products and degradation pathways of TCH were analyzed by LC–MS. The free-radical-quenching experiments revealed that both SO4− • and •OH radicals contributed to the degradation of TCH in the S–Fe/PDS system, with the former playing a more significant role. The S–Fe catalyst also showed good stability and reusability for the removal of organic pollutants. Our findings suggest that the modification of an iron-based catalyst offers an effective approach to activate persulfate for removal of tetracycline antibiotics.
A Complete Sojourn of Gene Therapy along with its Targeting Approaches
for the Treatment of the Major Depressive Disorder
Authors: Gupta G.D. , Singh Dilpreet
Published: June 2023

Approximately 2% to 3% of men and 6% to 7% of women suffer from severe depressive
disorders. The existing drugs only partially relieve symptoms for roughly 40% of these patients. The
majority of antidepressant drugs are based on theories that are now 50 to 60 years old, and the sector is
in critical need of new drug development targets. In the recent decade, numerous genes have been
connected to depression in animal models, and serious depression does run in families in humans, indicating
both a genetic and environmental component. Depression has been linked to the malfunctioning
of serotonin signaling genes, including p11, SERT, etc, according to earlier research. Gene therapy
for depression has been found in some instances to be relatively safe, despite the fact that it may seem
riskier and more invasive than medication. Hence, there is a growing field regarding the safest delivery
mechanisms of these genes that treat major depressive disorders permanently. Hence, the present
review summarized the delivery mechanisms of various genes responsible for depressive disorders
along with their molecular mechanisms and delivery at the cellular level.
The Rate of Insulin use and Suboptimal Glycemic Control among
Egyptian Patients with T2DM: Cohort Analysis of Eighth Wave of the
International Diabetes Management Practices Study (IDMPS)
Authors: Khalil Samir Helmy Assaad , Khaled Mohsen , Zakhary Raafat , Shereen Mark
Published: June 2023

Aims:

The International Diabetes Management Practices Study (IDMPS) is an international
annual survey aiming to study and characterize the current standards of care for managing
DM in developing countries.

Background:

In Egypt, DM represents a substantial burden on the healthcare system, with an estimated
10.9 million patients, ranking it 10th amongst countries with the highest prevalence of DM.
Previous studies showed that to maintain safety and achieve treatment goals among diabetic patients,
optimal insulin therapy should be selected individually based on the patient’s needs. We reported
the proportion of Egyptian T2DM patients on insulin therapy who participated in the eighth
wave of the IDMPS.

Methods:

The 2018 IDMPS wave consisted of cross-sectional and longitudinal phases and aimed
to evaluate the proportion of T2DM who were on insulin therapy in 13 countries from four regions.
In Egypt, 17 physicians agreed to participate in the present study and were required to include at
least one patient.

Results:

A total of 180 T2DM patients were included in the cross-section phase. At the end of the
ninth month of follow-up, data from 170 T2DM patients were available. A total of 39 T2DM patients
(21.7%) were on insulin therapy, with a mean duration of 32.4 ± 36.6 months. More than half
of the patients (n = 22; 56.4%) were on basal insulin, mainly long-acting (n = 20; 90.9%). The
mean basal insulin daily dose was 0.3 ± 0.1 IU/Kg. Notably, 28.2% of the patients received insulin
via vials, and 46.2% stated that they were adjusting the insulin dose by themselves. On the other
hand, 60.2% of the study population was on oral antidiabetic drugs at the cross-sectional phase.
Nearly 17.4% and 27% of the patients in the cross-sectional phase achieved the glycemic target per
recommendations of international guidelines and the treating physicians, respectively. At the end
of the longitudinal phase, the percentage of T2DM patients who achieved glycemic targets increased
to 38.4% and 77.4% as per recommendations of international guidelines and the treating
physicians, respectively. Overall, 38.3% of T2DM patients received diabetes education, and 28.9%
were involved in an educational program provided by the physician or their clinical staff. Besides,
85.5% of T2DM patients followed their diabetes medication dosage and frequency strictly as prescribed.

Conclusion:

The proportion of insulin use in patients with T2DM aligned with the previous studies
from different countries; however, it is still inadequate to achieve the targeted glycemic control.
Nearly one-third of Egyptian patients received diabetes education, highlighting the need for adopting
a national educational program. Nonetheless, the level of adherence among T2DM from Egypt
appears to be high.
Updates on the Interactions of Herbs Constituents with Cytochrome P450
Drug Metabolizing Enzymes
Authors: Zaroug Elwaleed Elamin Hassan , Albashir Tarig Omer Ahmed , Arbab Ahmed Hassan , Mudawi Mahmoud Mudawi Eltahir
Published: June 2023

Cytochrome P450 enzymes are the main drug-metabolizing enzyme, and their activity is influenced
by numerous factors, including several plants’ constituents. Herbal products mediated induction
or inhibition of cytochrome P450 leads to a change in drug metabolism and consequently, drug bioavailability,
safety, therapeutic efficacy, and herb-drug interaction. Since herbal preparations are commonly
used either alone or concomitantly with conventional drugs, understanding the interactions of
plant constituents with cytochrome P450 is crucial. Therefore, this review highlighted plants with significant
inhibition, induction, or modulatory /contradictory effects on human and animal cytochrome
P450 enzymes. An extensive literature search was conducted on PubMed, ScienceDirect, and Google
Scholar databases to identify relevant literature. About sixty medicinal plants with significant interaction
with cytochrome P450 isoforms were summarized with their common uses and affected cytochrome
P450 enzyme isoforms. Besides, representative examples of plant constituents and other factors
contributing to plant-induced cytochrome P450 modulation and possible herb-drug interactions were also
discussed in this review.
The Effect of Curcumin Nanoparticles on Paracetamol-induced Liver Injury
in Male Wistar Rats
Authors: Damayanti Irma Putri , Susilaningsih Neni , Nugroho Trilaksana , Suhartono Suhartono , Suryono Suryono , Susanto Hardhono , Suwondo Ari , Mahati Endang
Published: June 2023

Introduction:

Curcumin is a naturally occurring compound that has antioxidant properties,
acts as a hepatoprotective, and lowers lipid peroxidation. However, curcumin's low solubility and bioavailability
are its primary drawbacks and prevent its use as a therapeutic agent. In this study, curcumin
nanoparticles will be created using the ultrasonic-assisted extraction method, and their effectiveness
against paracetamol-induced changes in ALT, AST, SOD, MDA, and TNF-α will be compared to that
of pure curcumin.

Purpose:

This study aimed to determine the hepatoprotective effect of curcumin nanoparticles in paracetamol-
induced rats as a model for liver injury.

Methods:

Thirty-six male Wistar rats, aged 6 to 8 weeks, with a minimum weight of 120 grams, were
used in an experimental laboratory investigation with a post-test-only group design. Rats in each group
received 100 mg/kgBW pure curcumin, 100 mg/kgBW curcumin nanoparticles, and 50 mg/kgBW curcumin
nanoparticles for 7 days before paracetamol induction. On day 8, 300 mg/kgBW of paracetamol
was intraperitoneally injected to cause liver damage. One of the groups received NAC as an antidote 10
hours after paracetamol induction. Detection of ALT and AST using a Chemistry Analyzer. ELISA approach
for the detection of SOD, MDA, and TNF-α. The Roenigk score was calculated by two examiners
after the liver histopathology preparations were stained using the Hematoxylin-Eosin method. Post
hoc analyses were performed after the One Way Annova and Kruskal Wallis tests to examine the data.

Results:

According to PSA results, the smallest formula that formed curcumin nanoparticles (10.2 nm)
was 8 g of curcumin formula mixed with a mixture of Tween 20 4.5 ml, Kolliphor EL 1.5 ml, Propylene
Glycol 1.5 ml, and Capryol 90 1 ml for 21 minutes using an ultrasonic process. MDA and TNF-α levels,
as well as the liver's histological Roenigk score, were significantly lower in the 100 mg/kgBB pure curcumin
group (C100) when compared to the model group (model). The levels of AST, MDA, TNF-α,
and the liver histopathology score were significantly lower in the 100 mg/kgBB (NC100) and 50
mg/kgBB (NC50) curcumin nanoparticle groups compared to the model group (model) and pure curcumin
group (C100) (p< 0.05).
Survey on the Techniques for Classification and Identification of Brain
Tumour Types from MRI Images Using Deep Learning Algorithms
Authors: K. Gayathri Devi , Balasubramanian Kishore
Published: June 2023

A tumour is an uncontrolled growth of tissues in any part of the body. Tumours are of
different types and characteristics and have different treatments. Detection of a tumour in the earlier
stages makes the treatment easier. Scientists and researchers have been working towards developing
sophisticated techniques and methods for identifying the form and stage of tumours. This
paper provides a systematic literature survey of techniques for brain tumour segmentation and classification
of abnormality and normality from MRI images based on different methods including
deep learning techniques. This survey covers publicly available datasets, enhancement techniques,
segmentation, feature extraction, and the classification of three different types of brain tumours
that include gliomas, meningioma, and pituitary and deep learning algorithms implemented for
brain tumour analysis. Finally, this survey provides all the important literature on the detection of
brain tumours with their developments.
Factors Affecting Speech Delay In Toddlers
Authors: Aulia Farza , Ain Hurun , Pujiastuti Nurul
Published: June 2023

The problem of speech delays in preschool children is estimated at 5% of the normal population. It is known that 19% of toddlers have speech and language development disorders, with details of 6.4% speech delay, 4.6% speech and language delay, and 6% language delay. This study aimed to identify factors associated with speech delay in toddlers. This study uses the Literature Review design. The article was taken from the SINTA, Garuda, PubMed, Science Direct, and Google Scholar databases with the keywords (((speech delay) AND toddler) AND influencing factors). The criteria for the articles used are 2018-2021 publications. The articles were selected using the PEOS framework and the JBI Critical Appraisal tools. The results showed that the factors that influenced the occurrence of speech delays included two articles related to gender, one article related to the incidence of physical trauma, two articles related to genetic factors, two articles related to neurological disorders, three articles related to the use of gadgets, and six articles related to parenting. Suggestions that further research can be carried out on the effect of implementing parenting patterns on speech delays in toddlers.
Nursing Students’ Learning Support, Outcome, and Satisfaction Towards Online Learning
Authors: Ariningpraja Rustiana Tasya , Wisnasari Shila
Published: June 2023

Online learning in nursing education has been carried out for a long time by several educational institutions worldwide. However, online learning in Indonesia has been forced to take place since the Coronavirus Disease 2019 pandemic was announced. This study aims to determine how students perceive learning support and how it relates to learning outcomes and student satisfaction in online learning that has been implemented for the even semester of 2021. This study involved 160 respondents willing to participate in filling out statements related to online learning support, Grade Point Average (GPA), and satisfaction. The data were analyzed using the Pearson test. The results showed a positive correlation between support for nursing student satisfaction during online learning (p<0.05). However, this study's support did not correlate with learning outcomes (p>0.05). Most nursing students perceive instructional, lecturer, peer, and technical support positively. A detailed explanation of why the results of this study are important and discussed in the article. In conclusion, educational institutions must periodically evaluate students' perceptions of learning support, which is not only limited to online learning but also blended learning which is likely to be applied. In addition, satisfaction can also help assess how to provide an overview of students' views as regular customers at nursing education institutions.
The Knowledge Level of Pregnant Mothers About Preeclamsia at The Clinic in Tondano Minahasa Regency
Authors: Simanjuntak Herlina Sarista , Rotinsulu Jelica Jenifer , Wulandari Veronika Ani , Cathryne Joice , Anggraini Mega Tri
Published: June 2023

Preeclampsia is a health problem that is often found in pregnant mothers. Indonesia has 76.000 women and 500.000 infant deaths caused by preeclampsia every year. Based on an interview with a nurse clinic in Tondano Minahasa Regency, 25 of 50 women during pregnancy have preeclampsia. This study aimed to find the knowledge level of pregnant mothers about preeclampsia at a Clinic in Tondano Minahasa Regency. This study used a descriptive quantitative method with a univariate data analysis technique. The sample of this study is 50 pregnant women willing to be respondents and registered at Clinic in Tondano Minahasa Regency with accidental sampling as the sampling method. The instrument of this study uses a questionnaire about the knowledge level of pregnant mothers about preeclampsia. The result of this research shows that 35 (70%) pregnant mothers had good knowledge, 11 (22%) pregnant mothers had a moderate amount of knowledge, and 4 (8%) pregnant mothers had insufficient knowledge about preeclampsia. Institutions can use the results of this study to increase pregnant mothers' knowledge about preeclampsia through education, and it can also be used as overview knowledge about preeclampsia for the public. Future research can use this study as a reference for prospective studies about the incidence of preeclampsia with different variables.
Persepsi guru bahasa Indonesia SMA terhadap penilaian literasi membaca berbasis keterampilan aras tinggi
Authors: Wahyudi Diki , Ristanti Widya , Suwandi Sarwiji
Published: June 2023

Penelitian ini dilatarbelakangi wacana diberlakukannya kurikulum prototipe di semua jenjang, baik jenjang sekolah dasar maupun sekolah menengah. Ciri khas pembelajaran dan penilaian pada kurikulum tersebut ialah pembelajaran berbasis literasi. Penelitian ini bertujuan menganalisis persepsi Guru Bahasa Indonesia SMA terhadap penilaian literasi membaca berbasis keterampilan berpikir aras tinggi (higher order thinking skill/ HOTS). Metode penelitian ini menggunakan analisis deskriptif kualitatif dengan pendekatan studi kasus eksploratif. Fokus penelitian terhadap penilaian literasi membaca berbasis keterampilan berfikir aras tinggi. Teknik pengumpulan data menggunakan angket semi terbuka dan wawancara. Hasil penelitian menunjukkan bahwa Guru Bahasa Indonesia SMA di Kota Surakarta sudah menyadari pentingnya literasi membaca untuk dibelajarkan, guru juga sudah mengintegrasikan literasi membaca dalam pembelajaran Bahasa Indonesia, guru sudah menerapkan pembelajaran berbasis keterampilan aras tinggi, dan dalam hal penilaian guru sudah menerapkan penilaian literasi membaca berbasis keterampilan aras tinggi. Dengan demikian, penilaian literasi membaca berbasis keterampilan berpikir aras tinggi sudah diimplementasikan dalam pembelajaran, khususnya pembelajaran Bahasa Indonesia SMA di Kota Surakarta.Kata kunci: persepsi guru, penilaian, literasi membaca, keterampilan berpikir aras tinggi, HOTS PERCEPTIONS OF HIGH SCHOOL INDONESIAN TEACHERS TOWARDS READING LITERACY ASSESSMENT BASED ON HIGHER ORDER THINKING SKILLAbstractThis research is motivated by the discourse of the implementation of the prototype curriculum at all levels, both elementary and high school levels. The hallmark of learning and assessment in the curriculum is literacy-based learning. This study aims to analyze the perception of Indonesian high school teachers on reading literacy assessments based on higher order thinking skills (HOTS). This research method uses descriptive qualitative analysis with an exploratory case study approach. The focus of the research is on the assessment of reading literacy based on high-level thinking skills. Data collection techniques used semi-open questionnaires and interviews. The results of the study show that Indonesian high school teachers in Surakarta City have realized the importance of reading literacy to be taught, teachers have also integrated reading literacy in Indonesian language learning, teachers have implemented high-level skills-based learning, and in terms of teacher assessments have implemented reading literacy assessments based on high level skills. Thus, an assessment of reading literacy based on high-level thinking skills has been implemented in learning, especially learning Indonesian in SMA in Surakarta City.Keywords: teacher perception, assessment, reading literacy, high order thinking skills, HOTS
Coping with emotions in professional lives: Novice teachers’ voices in Indonesian secondary schools
Authors: Limeranto Jeane Theresia , Kuswandono Paulus
Published: June 2023

Novice teachers often encountered some challenges in their professional work that might influence their emotions.  It is quite reasonable that some EFL novice teachers may still struggle to manage their negative emotions to cope with classroom problems. Some emotions could be freely expressed positively, whereas other emotions were left unexpressed for some reasons. This study aimed to answer two research questions, namely: (1) what kinds of emotions do novice teachers frequently experience in teaching? (2) How do novice EFL teachers cope with their emotions in professional life? This study employed a qualitative method and carried out semi-structured interviews to gain in-depth data from the participants' perspectives in dealing with their emotions. The instruments employed were interview-guidelines questions and open-ended questions. The result of the present study revealed that, first, all novice teachers frequently experienced two main challenges in teaching, namely students’ misbehaviours and disrespectful behaviours. These challenges could influence teachers' emotions of anger, being overwhelmed, and worries. Second, the findings demonstrated that teachers employed three strategies, namely self-regulation, self-talk, and a problem-focused strategy to manage and handle their emotions in teaching. In addition, the present study suggested beneficial implications, limitations, and directions for further research. Keywords: Emotions, EFL Novice Teachers, and Strategies
Solitary Metastasis in the Tibia as a Feature of Primary Squamous Vaginal Carcinoma
Authors: Pavić Mamula Jelena , Tkalčić Lovro , Miletić Damir , Veljković Vujaklija Danijela
Published: June 2023

Aim: Primary vaginal cancer is rare, comprising about 3% of all gynaecological malignancies. Solitary bone metastases to appendicular skeleton are extremely rare and there are only few published reports. We report the case of isolated metastasis in the tibia as a feature of primary squamous vaginal carcinoma. We present this case because of its rarity and for documentation and discussion purposes. Case report: We present a case of a 44-year old woman diagnosed with squamos vaginal cancer in June 2015. Computed tomography of the thorax, abdomen and pelvis revealed no distant metastases. She was treated with interstitial intracavitary brachytherapy and concomitant chemoradiotherapy. In March 2016 she was admitted to our hospital because of the swelling and the pain in the lower right leg. There was no history of trauma and plain radiographs were normal. Two months later, after further progression of pain, plain radiographs showed intramedullary permeative bone lesion with cortical disruption of tibial dyaphisis and local soft tissue swelling. MRI and core needle biopsy confirmed vaginal cancer metastasis containing tumor cells identical to the primary tumor. The patient was treated with radiotherapy and chemotherapy. Despite the treatment there was further progression of the disease with multiple bone metastases and eventually lung and brain metastases. Conclusion: This case report is another reminder that although extremely rare, solitary metastatic bone lesions of vaginal cancer are possible. Since symptoms mimic various benign conditions, it is important to consider bone metastasis as possible diagnosis in patients with progressive bone pain not responding to analgesic treatment.
The strategic position of health and wellness tourism in the development of the Douro Demarcated Region World Heritage Site
Authors:   CEGOT, Faculty of Arts and Humanities, University of Porto, Portugal, Pina Helena , Martins Felisbela ,   CEGOT, Faculty of Arts and Humanities, University of Porto, Portugal
Published: June 2023

In a wine producing region like the Douro Valley (NE Portugal), embedded in the schist-greywacke complex of the Douro-Beira district and the source of high-quality mineral and spring waters, what is the strategic positioning of health and wellness tourism? What is the importance of thermal baths in the revitalisation of rural areas, and who are the main agents behind these dynamics? These are the main questions we will address in this article. Relatively overlooked until recently, health and wellness tourism has been growing in relevance in Europe and Portugal in the 21st century and is now considered a strategic product. Thermal baths were traditionally restricted to therapeutical treatments, but well-being has become a core concern today. Thermal bathhouses and resorts can be found throughout Portugal, four of which are located in the Douro region. Furthermore, their revitalisation bolsters sustainable development of Portugal’s inland regions, “reclaiming” an activity with a centuries-long history under a new paradigm. To achieve the study’s goals, we have combined documentation research with fieldwork, including semi-structured interviews conducted with the main actors involved in these dynamics.
A Video-Observed Treatment Strategy to Improve Adherence to Treatment Among Persons Who Inject Drugs Infected With Hepatitis C Virus: Qualitative Study of Stakeholder Perceptions and Experiences (Preprint)
Authors: Karasz Alison , Merchant Krupa , Arnsten Julia , Feinberg Judith , Kim Arthur Y , Lum Paula J , McKee Melissa Diane , Mehta Shruti H , Meissner Paul , Norton Brianna L , Page Kimberly , Pericot-Valverde Irene , Singh Reena , Stein Ellen , Taylor Lynn E , Tsui Judith I , Wagner Katherine , Litwin Alain
Published: June 2023

BACKGROUND

Direct-acting antiviral medications have the potential to eliminate the hepatitis C virus (HCV) epidemic among people who inject drugs; yet, suboptimal adherence remains a barrier. Directly observed treatment (DOT), an effective strategy for optimizing adherence, has been frequently implemented in opioid treatment programs but less commonly in community health settings due to the heavy burden of daily visits. An alternative is video-observed therapy (VOT), which uses mobile health technology to monitor adherence. VOT has not been widely studied among people who inject drugs with HCV.

OBJECTIVE

This qualitative study, part of a larger implementation evaluation, investigates stakeholder perceptions and experiences with VOT in Project HERO (Hepatitis C Real Outcomes), a multisite pragmatic trial testing treatment delivery models for people who inject drugs with HCV. Our goal was to understand the potential barriers and facilitators to the implementation of the VOT technology.

METHODS

Qualitative interviews were conducted with 27 Project HERO study staff and 7 patients. Interviews focused on perceptions and experiences with the VOT app and barriers and facilitators to implementation. Team meeting minutes over the first 2 years of the project were transcribed. A coding system was developed and applied to the data. We summarized thematic data and compared participant perceptions to generate a close understanding of the data.

RESULTS

Frequent barriers to VOT included mechanical failure, stolen or lost phones, and a steep learning curve for participants and study staff. In sites with older and less technically skilled participants, staff found it difficult to implement the VOT app. Research staff found that the routine monitoring of app use led to closer engagement with participants. This was both a benefit and a potential threat to the validity of this pragmatic trial. Patient participants reported mixed experiences.

CONCLUSIONS

VOT may be a useful alternative to DOT for some patients, but it may not be feasible for all. Significant staff involvement may be required.

CLINICALTRIAL
Use of Machine Learning Tools in Evidence Synthesis of Tobacco Use Among Sexual and Gender Diverse Populations: Algorithm Development and Validation (Preprint)
Authors: Ma Shaoying , Jiang Shuning , Yang Olivia , Zhang Xuanzhi , Fu Yu , Zhang Yusen , Kaareen Aadeeba , Ling Meng , Chen Jian , Shang Ce
Published: June 2023

BACKGROUND

From 2016 to 2021, the volume of peer-reviewed publications related to tobacco has experienced a significant increase. This presents a considerable challenge in efficiently summarizing, synthesizing, and disseminating research findings, especially when it comes to addressing specific target populations, such as the LGBTQ+ (lesbian, gay, bisexual, transgender, queer, intersex, asexual, Two Spirit, and other persons who identify as part of this community) populations.

OBJECTIVE

In order to expedite evidence synthesis and research gap discoveries, this pilot study has the following three aims: (1) to compile a specialized semantic database for tobacco policy research to extract information from journal article abstracts, (2) to develop natural language processing (NLP) algorithms that comprehend the literature on nicotine and tobacco product use among sexual and gender diverse populations, and (3) to compare the discoveries of the NLP algorithms with an ongoing systematic review of tobacco policy research among LGBTQ+ populations.

METHODS

We built a tobacco research domain–specific semantic database using data from 2993 paper abstracts from 4 leading tobacco-specific journals, with enrichment from other publicly available sources. We then trained an NLP model to extract named entities after learning patterns and relationships between words and their context in text, which further enriched the semantic database. Using this iterative process, we extracted and assessed studies relevant to LGBTQ+ tobacco control issues, further comparing our findings with an ongoing systematic review that also focuses on evidence synthesis for this demographic group.

RESULTS

In total, 33 studies were identified as relevant to sexual and gender diverse individuals’ nicotine and tobacco product use. Consistent with the ongoing systematic review, the NLP results showed that there is a scarcity of studies assessing policy impact on this demographic using causal inference methods. In addition, the literature is dominated by US data. We found that the product drawing the most attention in the body of existing research is cigarettes or cigarette smoking and that the number of studies of various age groups is almost evenly distributed between youth or young adults and adults, consistent with the research needs identified by the US health agencies.

CONCLUSIONS

Our pilot study serves as a compelling demonstration of the capabilities of NLP tools in expediting the processes of evidence synthesis and the identification of research gaps. While future research is needed to statistically test the NLP tool’s performance, there is potential for NLP tools to fundamentally transform the approach to evidence synthesis.
Correction: Unassisted Clinicians Versus Deep Learning–Assisted Clinicians in Image-Based Cancer Diagnostics: Systematic Review With Meta-analysis (Preprint)
Authors: Xue Peng , Si Mingyu , Qin Dongxu , Wei Bingrui , Seery Samuel , Ye Zichen , Chen Mingyang , Wang Sumeng , Song Cheng , Zhang Bo , Ding Ming , Zhang Wenling , Bai Anying , Yan Huijiao , Dang Le , Zhao Yuqian , Rezhake Remila , Zhang Shaokai , Qiao Youlin , Qu Yimin , Jiang Yu
Published: June 2023

UNSTRUCTURED

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Effectiveness and Feasibility of Telehealth-Based Dietary Interventions Targeting Cardiovascular Disease Risk Factors: Systematic Review and Meta-Analysis (Preprint)
Authors: Trivedi Rupal , Elshafie Shaimaa , Tackett Randall , Young Henry , Sattler Elisabeth Lilian Pia
Published: June 2023

BACKGROUND

Telehealth-based dietary interventions were recommended for cardiovascular disease (CVD) management during the COVID-19 pandemic; however, data regarding their effectiveness and feasibility are limited.

OBJECTIVE

We aimed to examine (1) the effectiveness of telehealth-based dietary interventions in improving clinical CVD risk factors and (2) the feasibility of these interventions among individuals with CVD.

METHODS

To conduct this systematic review and meta-analysis of randomized controlled trials (RCTs), 2 investigators searched PubMed, Cochrane Library, Web of Science, and ClinicalTrials.gov databases based on predetermined search terms and included English-language RCTs published between January 2000 and July 2022. The Cochrane Risk of Bias tool was used to assess RCT quality. To evaluate intervention effectiveness, weight, BMI, systolic and diastolic blood pressure, and levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, or blood glucose were compared postintervention in telehealth and usual care (UC) groups. Feasibility was determined through the number of participants retained in intervention and UC groups. Pooled data for each CVD outcome were analyzed using a random effects model. Mean difference (MD), standardized MD, or risk ratio were calculated using R software.

RESULTS

A total of 13 RCTs with 3013 participants were included in the analysis to assess the effectiveness and feasibility of telehealth-based dietary interventions among individuals with CVD. Participants had a mean age of 61.0 (SD 3.7) years, and 18.5% (n=559) were women. Approximately one-third of RCTs were conducted in the United States (n=4, 31%). Included studies used telephone, app, text, audio-visual media, or website-based interventions. Of the 13 included studies, 3 were of high quality, 9 were of moderate quality, and only 1 was of low quality. Pooled estimates showed systolic blood pressure (MD –2.74, 95% CI –4.93 to –0.56) and low-density lipoprotein cholesterol (standardized MD –0.11, 95% CI –0.19 to –0.03) to be significantly improved among individuals with CVD as a result of telehealth-based dietary interventions compared to UC. No significant difference in effectiveness was detected for weight, BMI, and levels of diastolic blood pressure, total cholesterol, high-density lipoprotein, and triglycerides between telehealth-based dietary interventions and UC among those with CVD. There was no significant difference between the feasibility of telehealth-based dietary interventions versus UC. Significant I2 indicated moderate to considerable heterogeneity.

CONCLUSIONS

Telehealth-based dietary interventions show promise in addressing CVD risk factors.
Centering Public Perceptions on Translating AI Into Clinical Practice: Patient and Public Involvement and Engagement Consultation Focus Group Study (Preprint)
Authors: Lammons William , Silkens Milou , Hunter Jamie , Shah Sudhir , Stavropoulou Charitini
Published: June 2023

BACKGROUND

Artificial intelligence (AI) is widely considered to be the new technical advancement capable of a large-scale modernization of health care. Considering AI’s potential impact on the clinician-patient relationship, health care provision, and health care systems more widely, patients and the wider public should be a part of the development, implementation, and embedding of AI applications in health care. Failing to establish patient and public engagement and involvement (PPIE) can limit AI’s impact.

OBJECTIVE

This study aims to (1) understand patients’ and the public’s perceived benefits and challenges for AI and (2) clarify how to best conduct PPIE in projects on translating AI into clinical practice, given public perceptions of AI.

METHODS

We conducted this qualitative PPIE focus-group consultation in the United Kingdom. A total of 17 public collaborators representing 7 National Institute of Health and Care Research Applied Research Collaborations across England participated in 1 of 3 web-based semistructured focus group discussions. We explored public collaborators’ understandings, experiences, and perceptions of AI applications in health care. Transcripts were coanalyzed iteratively with 2 public coauthors using thematic analysis.

RESULTS

We identified 3 primary deductive themes with 7 corresponding inductive subthemes. Primary theme 1, advantages of implementing AI in health care, had 2 subthemes: system improvements and improve quality of patient care and shared decision-making. Primary theme 2, challenges of implementing AI in health care, had 3 subthemes: challenges with security, bias, and access; public misunderstanding of AI; and lack of human touch in care and decision-making. Primary theme 3, recommendations on PPIE for AI in health care, had 2 subthemes: experience, empowerment, and raising awareness; and acknowledging and supporting diversity in PPIE.

CONCLUSIONS

Patients and the public can bring unique perspectives on the development, implementation, and embedding of AI in health care. Early PPIE is therefore crucial not only to safeguard patients but also to increase the chances of acceptance of AI by the public and the impact AI can make in terms of outcomes.

CLINICALTRIAL