bluuebunny/crossref_metadata_2025 huggingface dataset:
Myocarditis in a Young Patient with Celiac Disease; A Case Report and Literature Review
Authors: Myrmel Gard M.S. , Lunde Torbjørn , Dizdar Vernesa , Larsen Terje H. , Saeed Sahrai
Published: February 2021

Myocarditis has numerous aetiologies, and Celiac Disease (CD) has been described as a rare cause. CD has received little attention in current guidelines and may be underdiagnosed. We report a case involving a 28-year-old male with myocarditis causing severe left ventricular dysfunction and dilatation that was probably related to CD. This case highlights the importance of screening for CD in patients presenting with myocarditis and signs of malabsorption when other common causes are excluded. Besides optimal medical treatment and cardiac resynchronization therapy, a gluten-free diet and immunosuppression may also be effective measures in the management of CD-related myocarditis.
Association between Health Literacy, Patient Activation, and Functional Capacity in Individuals with Rheumatoid Arthritis
Authors: Oliveira Isabela V. , do Nascimento Mariana M. G. , Kakehasi Adriana M. , de Morais Neves Carina , Silva Hagabo M. , Gonçalves Thuane S. , de Moura Aredes Raquel , de Oliveira Djenane R.
Published: February 2021

Objectives:

To describe health literacy, patient activation, and functional capacity in individuals with rheumatoid arthritis and to evaluate the associations of health literacy and activation level with functional capacity.

Methods:

A cross-sectional study involving patients with rheumatoid arthritis was carried out at the rheumatology service of a teaching hospital. Health literacy was assessed by applying the short version of the Test of Functional Health Literacy in Adults. Patient Activation was measured by using the summarized version of the Patient Activation Measure. The Health Assessment Questionnaire was applied to evaluate functional capacity. Sociodemographic and clinical variables were also collected to carried out univariate and multivariate analyses by using logistic regression.

Results:

The sample was composed of 179 patients, of whom 90.5% (n = 162) were women. The participants’ average age was 58.3 ± 11.4 years. The prevalence of patients with inadequate or marginal health literacy was high (67%). In contrast, 74% of the patients showed high activation levels. The average score on the Health Assessment Questionnaire was 1.08 ± 0.7. Adequate health literacy was negatively associated with higher Health Assessment Questionnaire scores (OR = 0.42; 95% CI 0.20 – 0.86; p = 0.018), and high activation levels were negatively associated with moderate to severe functional limitation (level 3/moderate activation level – OR = 0.24; 95% CI 0.10 – 0.56; p = 0.001; level 4/high activation level – OR = 0.22; 95% CI 0.08 – 0.50; p = 0.000).

Conclusion:

Health professionals must be aware of health literacy and activation levels of patients with rheumatoid arthritis, given that interventions to improve them represent an opportunity to increase functional capacity.
Postdata Colombia : ocho perfiles en un país conectado
Authors:   Universidad de Bogotá Jorge Tadeo Lozano, Arango Lozano Carlos Andrés , Calderón Prieto Lizeth Geraldine ,   Analista de Data en PHD, Romero Cepeda Carlos ,   Annalect, Sánchez Leiva Iván ,   Dentsu
Published: February 2021

¿Qué pasaría si nos diéramos cuenta de que tenemos comportamientos similares los unos con los otros cuando navegamos por internet? Podríamos enterarnos de que las razones que nos unen tienen que ver con nuestros sueños, temores y necesidades. En esta publicación, el lector podrá darse cuenta de que todos los usuarios de la red navegamos la nube con objetivos similares. Podrá Identificarse con uno de los ocho perfiles que, de acuerdo con herramientas analíticas y estudios de comportamientos, hemos formulado para entender cómo los colombianos hacemos uso del más potente instrumento que tiene la humanidad hoy por hoy.
“A Fine, Sunshiny Night": The Authorial Afterlife of Captain James Fitzjames of the Third Franklin Expedition
Authors: Kasten-Mutkus Kathleen
Published: February 2021

The Third Franklin Expedition of the British Royal Navy set sail in 1845 in search of the Northwest Passage.  There were no survivors of the expedition, and nearly all records associated with it were lost.  This personal and textual disappearance severed the narrative control of those who participated in the expedition and sought to write about their experiences.  This article examines the authorship and the authorial afterlife of Captain James Fitzjames, an officer of the Third Franklin Expedition, with an emphasis on the ways in which Fitzjames’ legacy has been contextualized and recontextualized across time, discourse, and format.
Solanum betaceum in vitro seed germination and seedling development in response to pregerminative treatments
Authors: Salazar-Vega K. S , Vaca, I.
Published: February 2021

Germination and seedling development are critical stages in the life cycle of plants. Insufficient seedling emergence and inadequate establishment of woody plants are significant constraints in producing crops such as tamarillo. The application of pregerminative protocols improves the germination percentage, reduces the seedling emergence time, and improves several species in vitro. The present study was conducted to contrast three pregerminative treatments on Solanum betaceum seeds. When evaluating the pregerminative treatments, treatment T3 (imbibition for 24 hours) obtained the best results, showing an average of 21.62 days to germination, 73% germinated seeds, and 2.31 leaves per explant.
Using a Personal Health Library–Enabled mHealth Recommender System for Self-Management of Diabetes Among Underserved Populations: Use Case for Knowledge Graphs and Linked Data
Authors: Ammar Nariman , Bailey James E , Davis Robert L , Shaban-Nejad Arash
Published: February 2021

Background

Traditionally, digital health data management has been based on electronic health record (EHR) systems and has been handled primarily by centralized health providers. New mechanisms are needed to give patients more control over their digital health data. Personal health libraries (PHLs) provide a single point of secure access to patients' digital health data and enable the integration of knowledge stored in their digital health profiles with other sources of global knowledge. PHLs can help empower caregivers and health care providers to make informed decisions about patients’ health by understanding medical events in the context of their lives.

Objective

This paper reports the implementation of a mobile health digital intervention that incorporates both digital health data stored in patients’ PHLs and other sources of contextual knowledge to deliver tailored recommendations for improving self-care behaviors in diabetic adults.

Methods

We conducted a thematic assessment of patient functional and nonfunctional requirements that are missing from current EHRs based on evidence from the literature. We used the results to identify the technologies needed to address those requirements. We describe the technological infrastructures used to construct, manage, and integrate the types of knowledge stored in the PHL. We leverage the Social Linked Data (Solid) platform to design a fully decentralized and privacy-aware platform that supports interoperability and care integration. We provided an initial prototype design of a PHL and drafted a use case scenario that involves four actors to demonstrate how the proposed prototype can be used to address user requirements, including the construction and management of the PHL and its utilization for developing a mobile app that queries the knowledge stored and integrated into the PHL in a private and fully decentralized manner to provide better recommendations.

Results

To showcase the main features of the mobile health app and the PHL, we mapped those features onto a framework comprising the user requirements identified in a use case scenario that features a preventive intervention from the diabetes self-management domain. Ongoing development of the app requires a formative evaluation study and a clinical trial to assess the impact of the digital intervention on patient-users. We provide synopses of both study protocols.

Conclusions

The proposed PHL helps patients and their caregivers take a central role in making decisions regarding their health and equips their health care providers with informatics tools that support the collection and interpretation of the collected knowledge. By exposing the PHL functionality as an open service, we foster the development of third-party applications or services and provide motivational technological support in several projects crossing different domains of interest.
Understanding Side Effects of Antidepressants: Large-scale Longitudinal Study on Social Media Data
Authors: Saha Koustuv , Torous John , Kiciman Emre , De Choudhury Munmun
Published: February 2021

Background

Antidepressants are known to show heterogeneous effects across individuals and conditions, posing challenges to understanding their efficacy in mental health treatment. Social media platforms enable individuals to share their day-to-day concerns with others and thereby can function as unobtrusive, large-scale, and naturalistic data sources to study the longitudinal behavior of individuals taking antidepressants.

Objective

We aim to understand the side effects of antidepressants from naturalistic expressions of individuals on social media.

Methods

On a large-scale Twitter data set of individuals who self-reported using antidepressants, a quasi-experimental study using unsupervised language analysis was conducted to extract keywords that distinguish individuals who improved and who did not improve following the use of antidepressants. The net data set consists of over 8 million Twitter posts made by over 300,000 users in a 4-year period between January 1, 2014, and February 15, 2018.

Results

Five major side effects of antidepressants were studied: sleep, weight, eating, pain, and sexual issues. Social media language revealed keywords related to these side effects. In particular, antidepressants were found to show a spectrum of effects from decrease to increase in each of these side effects.

Conclusions

This work enhances the understanding of the side effects of antidepressants by identifying distinct linguistic markers in the longitudinal social media data of individuals showing the most and least improvement following the self-reported intake of antidepressants. One implication of this work concerns the potential of social media data as an effective means to support digital pharmacovigilance and digital therapeutics. These results can inform clinicians in tailoring their discussion and assessment of side effects and inform patients about what to potentially expect and what may or may not be within the realm of normal aftereffects of antidepressants.
Automated Travel History Extraction From Clinical Notes for Informing the Detection of Emergent Infectious Disease Events: Algorithm Development and Validation
Authors: Peterson Kelly S , Lewis Julia , Patterson Olga V , Chapman Alec B , Denhalter Daniel W , Lye Patricia A , Stevens Vanessa W , Gamage Shantini D , Roselle Gary A , Wallace Katherine S , Jones Makoto
Published: February 2021

Background

Patient travel history can be crucial in evaluating evolving infectious disease events. Such information can be challenging to acquire in electronic health records, as it is often available only in unstructured text.

Objective

This study aims to assess the feasibility of annotating and automatically extracting travel history mentions from unstructured clinical documents in the Department of Veterans Affairs across disparate health care facilities and among millions of patients. Information about travel exposure augments existing surveillance applications for increased preparedness in responding quickly to public health threats.

Methods

Clinical documents related to arboviral disease were annotated following selection using a semiautomated bootstrapping process. Using annotated instances as training data, models were developed to extract from unstructured clinical text any mention of affirmed travel locations outside of the continental United States. Automated text processing models were evaluated, involving machine learning and neural language models for extraction accuracy.

Results

Among 4584 annotated instances, 2659 (58%) contained an affirmed mention of travel history, while 347 (7.6%) were negated. Interannotator agreement resulted in a document-level Cohen kappa of 0.776. Automated text processing accuracy (F1 85.6, 95% CI 82.5-87.9) and computational burden were acceptable such that the system can provide a rapid screen for public health events.

Conclusions

Automated extraction of patient travel history from clinical documents is feasible for enhanced passive surveillance public health systems. Without such a system, it would usually be necessary to manually review charts to identify recent travel or lack of travel, use an electronic health record that enforces travel history documentation, or ignore this potential source of information altogether. The development of this tool was initially motivated by emergent arboviral diseases. More recently, this system was used in the early phases of response to COVID-19 in the United States, although its utility was limited to a relatively brief window due to the rapid domestic spread of the virus. Such systems may aid future efforts to prevent and contain the spread of infectious diseases.
Implementation of Cognitive Behavioral Therapy in e–Mental Health Apps: Literature Review (Preprint)
Authors: Denecke Kerstin , Schmid Nicole , Nüssli Stephan
Published: February 2021

BACKGROUND

To address the matter of limited resources for treating individuals with mental disorders, e–mental health has gained interest in recent years. More specifically, mobile health (mHealth) apps have been suggested as electronic mental health interventions accompanied by cognitive behavioral therapy (CBT).

OBJECTIVE

This study aims to identify the therapeutic aspects of CBT that have been implemented in existing mHealth apps and the technologies used. From these, we aim to derive research gaps that should be addressed in the future.

METHODS

Three databases were screened for studies on mHealth apps in the context of mental disorders that implement techniques of CBT: PubMed, IEEE Xplore, and ACM Digital Library. The studies were independently selected by 2 reviewers, who then extracted data from the included studies. Data on CBT techniques and their technical implementation in mHealth apps were synthesized narratively.

RESULTS

Of the 530 retrieved citations, 34 (6.4%) studies were included in this review. mHealth apps for CBT exploit two groups of technologies: technologies that implement CBT techniques for cognitive restructuring, behavioral activation, and problem solving (exposure is not yet realized in mHealth apps) and technologies that aim to increase user experience, adherence, and engagement. The synergy of these technologies enables patients to self-manage and self-monitor their mental state and access relevant information on their mental illness, which helps them cope with mental health problems and allows self-treatment.

CONCLUSIONS

There are CBT techniques that can be implemented in mHealth apps. Additional research is needed on the efficacy of the mHealth interventions and their side effects, including inequalities because of the digital divide, addictive internet behavior, lack of trust in mHealth, anonymity issues, risks and biases for user groups and social contexts, and ethical implications. Further research is also required to integrate and test psychological theories to improve the impact of mHealth and adherence to the e–mental health interventions.
The Roles of General Health and COVID-19 Proximity in Contact Tracing App Usage: Cross-sectional Survey Study (Preprint)
Authors: Witteveen Dirk , de Pedraza Pablo
Published: February 2021

BACKGROUND

Contact tracing apps are considered useful means to monitor SARS-CoV-2 infections during the off-peak stages of the COVID-19 pandemic. Their effectiveness is, however, dependent on the uptake of such COVID-19 apps.

OBJECTIVE

We examined the role of individuals’ general health status in their willingness to use a COVID-19 tracing app as well as the roles of socioeconomic characteristics and COVID-19 proximity.

METHODS

We drew data from the WageIndicator Foundation Living and Working in Coronavirus Times survey. The survey collected data on labor market status as well as the potential confounders of the relationship between general health and COVID-19 tracing app usage, such as sociodemographics and regular smartphone usage data. The survey also contained information that allowed us to examine the role of COVID-19 proximity, such as whether an individual has contracted SARS-CoV-2, whether an individual has family members and colleagues with COVID-19, and whether an individual exhibits COVID-19 pandemic–induced depressive and anxiety symptoms. We selected data that were collected in Spain, Italy, Germany, and the Netherlands from individuals aged between 18 and 70 years (N=4504). Logistic regressions were used to measure individuals’ willingness to use a COVID-19 tracing app.

RESULTS

We found that the influence that socioeconomic factors have on COVID-19 tracing app usage varied dramatically between the four countries, although individuals experiencing forms of not being employed (ie, recent job loss and inactivity) consistently had a lower willingness to use a contact tracing app (effect size: 24.6%) compared to that of employees (effect size: 33.4%; P<.001). Among the selected COVID-19 proximity indicators, having a close family member with SARS-CoV-2 infection was associated with higher contact tracing app usage (effect size: 36.3% vs 27.1%; P<.001). After accounting for these proximity factors and the country-based variations therein, we found that having a poorer general health status was significantly associated with a much higher likelihood of contact tracing app usage; compared to a self-reported “very good” health status (estimated probability of contact tracing app use: 29.6%), the “good” (estimated probability: +4.6%; 95% CI 1.2%-8.1%) and “fair or bad” (estimated probability: +6.3%; 95% CI 2.3%-10.3%) health statuses were associated with a markedly higher willingness to use a COVID-19 tracing app.

CONCLUSIONS

Current public health policies aim to promote the use of smartphone-based contact tracing apps during the off-peak periods of the COVID-19 pandemic. Campaigns that emphasize the health benefits of COVID-19 tracing apps may contribute the most to the uptake of such apps. Public health campaigns that rely on digital platforms would also benefit from seriously considering the country-specific distribution of privacy concerns.
Knowledge, Attitude, Practice and Associated Factors of Adult Population towards Blood Donation in Jigjiga Town, Somali Region, Ethiopia
Authors: Jibril Abdireshid Dahir , Mohammed Ahmed , Hashi Abdiwahab , Omer Muktar , Shegere Mekonin Meskelu , Joseph Nisha Mary , Palani S.
Published: February 2021

Background: Secure supply of safe blood components, based on voluntary, non-remunerated blood donation, is an important national goal to prevent blood shortages. Nowadays, in many low- and middle-income countries, blood supply is critically inadequate. Sub-Saharan Africa, which has the highest maternal mortality rate in the world of 510 deaths per 100000 live births, also has the lowest blood donation rates. The donated blood plays a big role during surgery, accident, delivery cases and in many bleeding cases.

The aim of this work is to assess knowledge, attitude, and practice and associated factors of adult population towards blood donation in Jigjiga town, Eastern Ethiopia, 2019. A total of20 kebeles, six was selected  by simple random sampling. The sample size was calculated by using EPI info version 7.2by considering power of 80%, confidence level of 95%, by taking the comprehensive knowledge of the study Participants towards voluntary blood donation of 43.5% from study conducted in Harartown, giving totalsample size of416. 

Result: About 249(61.2%), 318 (78.1%), and 77 (18.9%) study participants had adequate knowledge, good attitude and experience of blood donation. Those who were in college and higher education were 2.034 higher odds of knowledge towards blood donation relative to those in secondary and primary education. Study participants who were government employees and daily workers were 2.259(1.103, 4.629) times more knowledgable to housewife, students. Study particpants age range between 18-30 have less knowledge towards blood donation 0.408 times. Participants who attended college and higher education were more likely to have good attitude towards blood donation. Those respondents who are college and higher education and secondary were 2.450 times more likely, 2.359to have good attitude towards blood donation compared to primary school 2.161 respectively. Participant’s sex, education, and occupational status were found to be significantly associated with practice of blood donation. Being NGO worker is more likely to donate blood 8.167 higher than others. Male participants was more vulnarable to donate blood 5.245 times higher than female for blood do nation. In addition to this, those respondents who are graduated college and higher education were more likely to donate blood than others 3.247.
A Review of Novel Drug Delivery Controlled Porosity Osmotic Pump Tablets Therapeutic Approach and Future Trend
Authors: Shah Kinjal H , Makwana Rajeshree  P
Published: February 2021

The review work is comprised the enhancement of bioavailability and increase therapeutic efficacy. The porous osmotic pump tablets were designed using D‐Optimal design and numerical optimization technique was applied to find out the best formulation.  Another hand an osmotic pump (OP) were designed and evaluated with the aim to deliver drug in a controlled manner. Osmotic agent and pore former was considered as independent variables. Drug release rate at 2 h, 4 h, 8 h, 12 h, T50% and release exponent (n) were taken as responses. The increase in concentration of pore former and osmotic agent after a limit, changes the release was measured. The optimized formulation follows mechanism measured. The FT‐IR and DSC studies revealed that no physicochemical interaction between excipients and drug. The influence of pH and agitation intensity on the release of drug was studied and the release mechanism was through osmosis. Stability studies revealed that optimized formulation was stable. The result of D‐ Optimal design and ANOVA studies reveals that osmotic agent and pore former have significant effect on the drug release up to 12 h. The observed independent variables were found to be very close to predicted values of most satisfactory formulation which demonstrates the feasibility.

Keywords: osmotic pump, pore former, bioavailability
Gully erosion in Northeast China -- a case study on history, erosion rates and causes
Authors: WEN Yanru , Kasielke Till , Li Hao , Zepp Harald , Zhang Bin
Published: February 2021

Mollisols are of major importance for food security worldwide but are
increasingly degraded by soil erosion. Mollisols in Northeast China have
been converted into agricultural use only recently, but gullies are
widely distributed and gully erosion history, rates and causes remained
unclear. We chose a study typical village to estimate initiation years
and development rates of the gully systems from 1968 to 2018 by using
aerial and satellite imagery. The outlet fan deposits of a large gully
system were dated by Caesium-137 (137Cs) and artefacts. To verify the
results, we collected information from local farmers. Gully volumes were
measured by structure-from-motion technique using photos taken from an
unmanned aerial vehicle. Our results showed that gully systems had
already appeared on the steep slopes and along unpaved roads in 1968 and
had become more complex by 2018 despite terracing and afforestation.
Based on gully morphology and 137Cs, gully erosion was estimated to have
started in the 1950s to 1960s when the original grassland and forest
were completely converted into arable land. From 1968 to 2018, the gully
density increased from 1.2 to 2.3 km km-2. The gully heads retreated at
speeds from 1.5 to 2.5 m yr-1, and the soil loss from gully erosion
ranged from 25.7 to 44.7 Mg yr-1 ha-1. These data demonstrate the
severity of gully erosion in study region and underline the importance
of appropriate countermeasures, such as maintenance of abandoned
terraces under reforested land and better design and construction of
roads within the arable land.
A novel scoring system for vestibular schwannomas to identify candidacy for cochlear implantation
Authors: Dahm Valerie , Schwarz-Nemec Ursula , Auinger Alice , Yildiz Erdem , Matula Christian , Arnoldner Christoph
Published: February 2021

Objectives Here we present the audiometric outcomes of patients
undergoing vestibular schwannoma resection and cochlear implantation. We
additionally reviewed preoperative audiometric and radiological data,
with the aim of developing a new scoring system to identify suitable
patients for this treatment course. Methods After translabyrinthine
vestibular schwannoma resection, cochlear nerve conduction was evaluated
using intraoperative electrically evoked brain stem response audiometry.
Patients with positive results received a cochlear implant. We evaluated
the preoperative audiometric results, and vestibular schwannoma size and
extension, to develop a new scoring system to identify patients with
higher likelihood of nerve integrity after tumor removal and subsequent
cochlear implantation. Results Seventeen patients with unilateral
sporadic vestibular schwannomas underwent translabyrinthine resection,
of whom ten received a cochlear implant. Ten patients are daily cochlear
implant users. The mean word recognition score ss 28% at 65 dB, and
52% at 80 dB. Nine of the ten patients have open-set speech
understanding. All patients whose vestibular schwannoma did not make
contact with the modiolus were able to receive a cochlear implant,
compared to none of the patients with modiolus infiltration. Tumor size
alone did not predict the probability of sparing the cochlear nerve.
Conclusions Simultaneous translabyrinthine vestibular schwannoma
excision and cochlear implantation based on intraoperative electrically
evoked brain stem response audiometry measurements is a good option for
hearing rehabilitation. Preoperative exact assessment of the vestibular
schwannoma extension, audiometric testing, and promontory stimulation
electrically evoked brain stem response audiometry could improve
preoperative patient selection and predict the possibility of cochlear
implantation.
Predictors for sexual dysfunction in the first year postpartum: a systematic review and meta-analysis
Authors: Cattani Laura , Maeyer Liza De , Verbakel Jan , Bosteels Jan , Deprest Jan
Published: February 2021

Background Pregnancy and childbirth increase the risk for pelvic floor
dysfunction, including sexual dysfunction. So far, the mechanisms and
the extent to which certain risk factors play a role, remain unclear.
Objectives In this systematic review of literature, we aimed to
determine the risk factors for sexual dysfunction in the first year
after delivery. Search Strategy We searched MEDLINE, Embase and CENTRAL
using the search strategy: Sexual dysfunction AND Obstetric events.
Selection Criteria We included original English, comparative studies
that used validated questionnaires and the ICS/IUGA terminology for
sexual dysfunction, dyspareunia and vaginal dryness. Data Collection and
Analysis We assessed the quality and the risk of bias of the included
studies with the Newcastle Ottawa Scale. We extracted the reported data
and we performed random-effects meta-analysis to obtain the summary Odds
Ratios (OR) with 95% Confidence Intervals. Heterogeneity across studies
was assessed using the I2 statistic. Main Results We found no
significant difference in the odds for both sexual dysfunction and
dyspareunia between cesarean section and spontaneous delivery
(OR:1.17[0.88-1.57] and OR:0.75[0.53-1.07]) and between
operative delivery and spontaneous delivery (OR:1.56[0.87-2.79] and
OR:1.35[0.75-2.42]). Anal sphincter injury was associated with
increased odds for both sexual dysfunction (OR:3.00[1.28-7.03]) and
dyspareunia (OR:1.71[1.09-2.67]). Episiotomy was associated with
dyspareunia (OR:1.65[1.20-2.29]) but not with sexual dysfunction
(OR:1.90[0.94-3.84]). We retrieved one study of low quality which
reported on vaginal dryness and found no significant association with
obstetric events.
HUGE SPORADIC AND COMPLEX CARDIAC RHABDOMYOMA WITH HYPOPLASTIC LEFT VENTRICLE AND LEFT LUNG
Authors: Tansel Türkan , Demir İbrahim , Yazıksız Nilgün , Aydoğan Ümrah , Kalelioğlu İbrahim , Has Recep , Yılmazbayhan Emine
Published: February 2021

Cardiac rhabdomyomas are the most common fetal cardiac tumors and can be
diagnosed antenatally and postnatally by echocardiography. They are
usually asymptomatic and spontaneously regress within the first three
years of life and often associated with tuberous sclerosis (TS). The
prognosis of patients with rhabdomyomas is mostly determined by the size
and location of the lesion. Rhabdomyomas may cause hemodynamic
disturbances or arrhythmias due to obstructing the inflow or ventricular
outflow tracts or alter valve function, leading to poor prognosis.
Although it may regress spontaneously, surgical excision is usually
curative, especially in sporadic and single tumors. We report an unique
case of antenatally diagnosed as a huge cardiac rhabdomyoma accompanied
by hypoplastic left lung and left ventricle, mimicking significant
obstruction of the left ventricular and left atrial chamber. The patient
underwent urgent surgery, because of severe hemodynamic compromise on
the first day of life due to signs of severe obstruction of the left
ventricle and left atrium. The large, lobulated epicardial cardiac
rhabdomyoma located anterolateral and inferior aspect of the heart;
involved the whole left ventricle through the left atrium excised.
Neutrophil-to-Lymphocyte and Fibrinogen-to-Albumin Ratios are Important Indicators of Mortality in Patients with Coronavirus Disease 2019
Authors: ATLAS AHMET , Altay Nuray , karahan mahmut alp , Büyükfırat Evren , binici orhan , Pehlivan Veli , Pehlivan Başak , Duran Erdoğan , Erol Mehmet Kenan
Published: February 2021

Background: Coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a
pandemic. Early diagnosis of complications and mortality caused by this
disease will guide the treatment process in patients with COVID-19.
Materials and methods: In total, 102 adult patients (≥18 years) who were
followed up in the intensive care unit (ICU) between May and August 2020
because of COVID-19 were included in this study. Demographic data,
comorbid diseases, and hematological parameters of the patients during
admission to the ICU were examined. Hematological parameters such as
leukocyte, neutrophil, lymphocyte, platelet counts, C-reactive protein
(CRP), D-dimer, and lactate data were recorded. Neutrophil-to-lymphocyte
ratio (NLR) and fibrinogen-to-albumin ratio (FAR) were calculated, and
their effects on mortality were examined. Results: Of the patients, 71
(69.6%) were male and the mean age of all patients was 69.1 ± 14.3
(24–103) years. Comorbid diseases of the patients were as follows:
hypertension, 40 (39.2%) patients; diabetes mellitus, 28 (27.4%);
chronic obstructive pulmonary disease, 20 (19.6%); coronary artery
disease, 14 (13.7%), heart failure, 4 (3.9%), and cerebrovascular
disease, 3 (2.9%). Results showed that mortality was higher in patients
with older age (median age = 72; range = 62–80 years), and bilateral
infiltration was observed in lung computed tomography of all patients
who died. Mortality was higher in patients with NLR > 9.16,
FAR > 0.15, D-dimer > 2.01 mg/L, CRP
> 11.6 mg/dL, lactate > 2.3 mmol/L.
Conclusion: During the hospitalization of patients with COVID-19 to the
ICU, neutrophilia, lymphopenia, hyperfibrinogenemia, high NLR, FAR,
D-dimer, CRP, and lactate levels were found to be associated with
mortality. Keywords: COVID-19; D-dimer; fibrinogen-to-albumin ratio;
mortality factors; neutrophil-to-lymphocyte ratio
Solutions to a three phase-field model for solidification
Authors: Tang yangxin , Gao Wei
Published: February 2021

In this paper we present the phase-field models to describe
nonisothermal solidification of ideal multicomponent and multiphase
alloy systems. Governing equations are developed for the temporal and
spatial variation of three phase-field functions, as well as the
temperature field. The global existence of weak solutions to parabolic
differential equations in three dimension was proved by the Galerkin
method. The existence of a maximum theorem are also extensively studied.
Systemic pigmented contact dermatitis to cobalt following ingestion of cobalamin supplement
Authors: Pongcharoensuk Thanet , Thaiwat Supitchaya
Published: February 2021

Systemic contact dermatitis (SCD) is a condition occurring in previously
sensitized individuals after systemic re-exposure to the same or
cross-reacting substance. Pigmented systemic contact dermatitis after
intake of cobalt containing diet has never been reported.
Determination of Excess Removability of Self-Adhesive Resin Cements
Authors: Tran Duong
Published: February 2021

Objective: This study aimed to determine the force required to remove a defined amount of self-adhesive resin cements excess from a (pretreated) dentin surface after tack curing. Methods: Bovine teeth (n=5) were ground flat to expose dentin, polished (grit 320 sandpaper), distilled water rinsed, and gently air-dried. With the aid of a drilling template fixed with superglue (Sekundenkleber, Renfert GmbH), 1 to 3 cylindrical cavities (4.5±0.1mm diameter x 2.0±0.1mm depth) were drilled. Superglue was mechanically removed after drilling. Resin cement weighing 30mg was placed in the cavity and pushed through with a stainless-steel rod (4.0±0.05mm diameter x 2.0±0.1mm height), so that all of the excess cement was pushed out onto one side of the cavity to form a half moon. Excess cement was cured for a defined time of 5 seconds, from a defined distance (2mm spacer) from the tooth surface using an EliparTM S10 light curing device (3M ESPE). Excess cement was sheared off using a jig (Zwick Z010, n=5; speed= 0.75mm/min). Maximum force (N) to shear off the excess cement was recorded. Results: Experimental Cement and Calibra® Universal were statistically lower in mean newton force than the other selfadhesive resin cements. TheraCem® Ca and RelyX™ Unicem 2 were not statically different from each other. Maxcem EliteTM Chroma and G-CEM LinkAce® were statistically lower than TheraCem® Ca and RelyX™ Unicem 2. Conclusion: A method was developed to quantify force needed to remove cement excess. Under standardized conditions, different levels of removal force were identified. PANAVIA™ SA Cement Plus, Calibra® Universal and Experimental Cement require a significantly lower force for excess removal. SpeedCEM® Plus and Maxcem EliteTM Chroma require an intermediate force. RelyX™ Unicem 2 and TheraCem® Ca require a significantly higher force to achieve excess removal. Excess removal force can be lowered by reducing irradiation time as shown with RelyX™ Unicem 2 (one second cure) and RelyX™ Unicem 2 (two second cure).
Effect of Surface Treatments on the Flexural Strength of HeatPressed Zirconia Reinforced Lithium Silicate Ceramic and HeatPressed Lithium Disilicate Ceramic
Authors: Hakim Adnan
Published: February 2021

Objective: To compare the flexural strength of heat-pressed zirconia-reinforced lithium silicate (Celta Press) with that of heatpressed lithium disilicate (IPS e.max Press) and to evaluate the effect of surface treatments. Materials and Methods: Sixty-four specimens, with dimensions of 14.5 x 12.5 mm and 1.5 mm thickness, were fabricated using the lost-wax heat press technique and were divided into two groups: Group 1, Celta Press and Group 2, IPS e.max Press. Each group had four subgroups according to the surface treatment protocols: No treatment (A); Polished (B); Glazed (C), and Polished and Glazed (D). The specimens’ flexural strength was calculated by a universal testing machine in MPa. Results: IPS e.max Group D, showed the greatest flexural strength (374.22 ± 87.35MPa), while Celtra Press Group C, had the lowest flexural value (164.10 ± 51.97MPa). A two-way ANOVA indicated that IPS e.max exhibited statistically significantly greater flexural strength than Celtra Press. Tukey’s HSD test revealed that the polished and glazed group displayed greater flexural strength than the untreated group. Conclusion: IPS e.max Press showed greater flexural strength than Celtra Press among all groups. The combination of a polished and glazed surface produced greater flexural strength than the untreated group. Clinical Significance: With newer dental ceramic materials constantly emerging, there is a need to evaluate their mechanical properties and provide clinical recommendations. The aim of this in vitro study is to compare the flexural strength of two highly esthetic ceramic materials, Celtra Press and IPS e.max Press, and to offer some guidelines regarding their surface treatment protocol.
Evaluación del lenguaje en preescolares del norte de la ciudad de Durango, Durango, México
Authors: Reyes-Verdín Flor Dayana , Ríos-Valles José Alejandro , Salas-Name Sagrario Lizeth , Soto-Rivera Jesús Abraham , Herrera-Vargas Isela Vanessa
Published: February 2021

El porcentaje de niños latinoamericanos en edad preescolar con deficiencia en el desarrollo del lenguaje oscila entre 10 % y 80 %. Objetivo: Conocer el porcentaje de deficiencia en el lenguaje de niños preescolares del norte de la ciudad de Durango, Durango (México), para lo cual se empleó el cuestionario de madurez neuropsicológica infantil. Metodología: El estudio fue no experimental, observacional, transeccional y descriptivo, en un universo de trabajo de 833 niños, para lo que se consideró 95 % de confiabilidad en una muestra estadísticamente significativa de 214 participantes; sin embargo, debido a la culminación del ciclo escolar, solo fue posible evaluar a 148 participantes en el periodo de noviembre de 2017 a junio de 2018. El grupo estudiado fue dividido en 4 subgrupos: 55-60 meses de edad, 61-66 meses de edad, 67-72 meses de edad y 73-78 meses de edad.

Resultados: El alfa de Cronbach de las variables estudiadas fue 0.618. Se observaron deficiencias en las dos áreas del lenguaje evaluadas: lenguaje verbal y lenguaje no verbal. En los cuatro grupos estudiados, la mayor deficiencia se observó en el área del lenguaje verbal con porcentajes que oscilaron entre -80.5 % y -95.9 % en fluidez verbal; lenguaje expresivo con -27.5 % al -55.2 %; lenguaje comprensivo con -15.7 % al -31.1 % y lenguaje articulatorio con -14.1 % al -19.3 %. Las demás variables del grupo de lenguaje no verbal —estructuración espacial, psicomotricidad, visopercepción y memoria icónica— presentaron porcentajes de deficiencia menores a los observados en las variables de lenguaje verbal, aunque se destacan atención con -39.5 % al -43.2 %, ritmo con -2.9 % al -34.5 %, visopercepción con -10.6 % al -25.7 %, estructuración espacial con -3.5 % al -11.1 %, memoria icónica con -6.8 %, psicomotricidad con -3.6 %. Todos los grupos de edad estudiados presentaron deficiencia en seis o más variables del instrumento de evaluación empleado. Las variables del lenguaje no verbal que presentaron resultados satisfactorios por grupo de meses de edad fueron las siguientes: estructuración espacial en el grupo de 55-60 y en el de 67-72; psicomotricidad en el grupo de 55-60, 61-66 y 67-72; visopercepción en el grupo de 55-60; memoria icónica en los grupos de 55-60 y 67-72. Conclusión: De las áreas de lenguaje evaluadas, la de mayor afectación fue lenguaje verbal, lo cual permite considerar la necesidad de implementar la evaluación del desarrollo del lenguaje en la población infantil preescolar para considerar la oportunidad de optimizarlo.
Theoretical Studies of DENOx SCR over Cu-, Fe- and Mn-FAU Catalysts
Authors:   Faculty of Chemical Engineering and Technology, Cracow University of Technology, 24, Warszawska St., 31-5 155 Kraków, Poland, Kurzydym Izabela , Czekaj Izabela ,   Faculty of Chemical Engineering and Technology, Cracow University of Technology, 24, Warszawska St., 31-5 155 Kraków, Poland
Published: February 2021

Ab initio calculations based on the density functional theory were used. A cluster model of the faujasite zeolite structure (Al2Si22O66H36) with metal particles adsorbed above the aluminium centres was used. The NO and NH3 adsorption processes, individual and co-adsorption, have been studied over metal nanoparticles bound into zeolite clusters. Several configurations, electronic structure (charges, bond orders) and vibration frequencies have been analyzed to determine feasible pathways for the deNOx reaction. The M2O dimers (M = Cu, Mn or Fe) were considered in relation to the previous studies of iron complexes.
The Development, Evaluation, and Antioxidant Activity Analysis of Chitosan Microcapsules Containing Red Ginger Oleoresin with Sodium Tripolyphosphate Prepared by Emulsion Cross-linking Technique
Authors:   Chemical Engineering Department, Faculty of Engineering, Universitas Gadjah Mada Jl. Grafika No. 2, Yogyakarta, Indonesia, Jayanudin Jayanudin ,   Chemical Engineering Department, Faculty of Engineering, Universitas Sultan Ageng Tirtayasa Jl. Jenderal Sudirman km.3, Cilegon, Indonesia, Fahrurrozi Mohammad ,   Chemical Engineering Department, Faculty of Engineering, Universitas Gadjah Mada Jl. Grafika No. 2, Yogyakarta, Indonesia, Wirawan Sang Kompiang ,   Chemical Engineering Department, Faculty of Engineering, Universitas Gadjah Mada Jl. Grafika No. 2, Yogyakarta, Indonesia, Rochmadi Rochmadi ,   Chemical Engineering Department, Faculty of Engineering, Universitas Gadjah Mada Jl. Grafika No. 2, Yogyakarta, Indonesia
Published: February 2021

In this study, chitosan-based carrier of red ginger oleoresin was prepared using the emulsion cross-linking technique with sodium tripolyphosphate (TPP) as a cross-linking agent. The effect of chitosan and TPP concentration, as well as pH on the encapsulation efficiency, particle size and characterization of chitosan microcapsule was determined. The antioxidant activity of microcapsules was analyzed. Chitosan microcapsules containing red ginger oleoresin were produced although with non-smooth surfaces.
The Study of the Influence of Chemical Nature of Functional Groups in Oligomeric and Low--Molecular Modifiers on the Rheological Properties of the Epoxy Oligomer
Authors:   Kharkiv National University of Civil Engineering and Architecture, 40, Sumska St., Kharkiv, Ukraine, Barabash Elena , Popov Yuriy ,   Kharkiv National University of Civil Engineering and Architecture, 40, Sumska St., Kharkiv, Ukraine, Danchenko Yuliya ,   Kharkiv National University of Civil Engineering and Architecture, 40, Sumska St., Kharkiv, Ukraine
Published: February 2021

The influence of chemical nature of modifier functional groups on the level of intermolecular interactions in the system "epoxy oligomer ‒ modifier", as well as the structure formation and dynamic viscosity of epoxy oligomer has been studied in detail. Modifying additives in low concentrations contribute to an increase in the degree of structure formation of the epoxy system by increasing the intermolecular interaction between the associates of the epoxydiane oligomer. It was established that the strength of the formed coagulation structures depends both on the compatibility parameter of the modifiers and ED-20, and on their intermolecular interaction energy.
Heat Transfer Process During Filtration Drying of Grinded Sunflower Biomass
Authors:   Lviv Polytechnic National University, 12, Bandery St., 79013 Lviv, Ukraine, Kindzera Diana , Hosovskyi Roman ,   Lviv Polytechnic National University, 12, Bandery St., 79013 Lviv, Ukraine, Atamanyuk Volodymyr ,   Lviv Polytechnic National University, 12, Bandery St., 79013 Lviv, Ukraine, Symak Dmytro ,   Lviv Polytechnic National University, 12, Bandery St., 79013 Lviv, Ukraine
Published: February 2021

Filtration drying of grinded sunflower stems as the unit operation of the technological line for solid biofuel production has been proposed. Theoretical aspects of heat transfer processes during filtration drying have been analyzed. The effect of the drying agent velocity increase from 0.68 to 2.05 m/s on the heat transfer intensity has been established. The values of heat transfer coefficients have been calculated on the basis of the thin-layer experimental data and equation . Calculated coefficients for grinded sunflower stems have been correlated by the dimensionless expression within Reynolds number range of and the equation has been proposed to calculate the heat transfer coefficients, that is important for forecasting the heat energy costs at the filtration drying equipment design stage.
Kinetic Regularities and Mathematical Modelling of Potassium Chloride Dissolution
Authors:   Lviv Polytechnic National University, 12, S. Bandera St., 79013 Lviv, Ukraine, Symak Dmytro , Sabadash Vira ,   Lviv Polytechnic National University, 12, S. Bandera St., 79013 Lviv, Ukraine, Gumnitsky Jaroslaw ,   Lviv Polytechnic National University, 12, S. Bandera St., 79013 Lviv, Ukraine, Hnativ Zoriana ,   Lviv Polytechnic National University, 12, S. Bandera St., 79013 Lviv, Ukraine
Published: February 2021

The dissolution process of potassium chloride particles in the apparatus with two-blade mechanical stirrer was investigated and the mass transfer coefficient was determined. The experimental results were generalized by criterion dependence. The independence of the mass transfer coefficient from the solid particles diameter was confirmed. A countercurrent process of potassium salt dissolution in two apparatuses with a mechanical stirring was considered. A mathematical model for countercurrent dissolution was developed and the efficiency of this process was determined.
Simultaneous Distal Radius Fracture with Acute Radial Artery Injury: Is it a Unique Complex Injury or a Misdiagnosis Lesion?
Authors: G Kastanis , A Pantouvaki , G Magarakis , C Chaniotakis , C Christoforidis , P Kapsetakis
Published: February 2021

In spite of the fact that distal radius fractures are one of the most common injuries in emergency department, when these injuries accompanied with radial artery laceration, consist a very unique problem concerning the diagnosis as much as the treatment management. While many reports exist in literature which present the vascular complication of radial artery after surgical management of distal radius fracture, only three studies analyzed this complex injury. The qualified treatment of isolated DRF has been clarified but when the fracture is associated with radial artery lesion the protocol of treatment remains unclear. The aim of this study is to analyze three cases with simultaneous injuries of DRF and radial artery and to analyze our results compared to those presented in literature referring to the incidence of rate and treatment management.