bluuebunny/crossref_metadata_2025 huggingface dataset:
A análise dos impactos socioeconômicos na estruturação do EIA/RIMA: a importância da Abordagem Humanista para a Sustentabilidade
Authors: Conde Leandro Carlos Dias
Published: March 2013

The present work deals with the defense of the humanistic approach in structuring the analysis of Environmental Impact Assessment (EIA) and its Environmental Impact Report (RIMA) in relation to socioeconomic impacts addressed to realize that the conventional approach does not account social demands, as only this new approach will in fact the sustainable nature of the EIA / RIMA.
Galileo, Gauss, and the Green Monster
Authors: Kalman Dan , Teague Daniel J.
Published: March 2013

Using ideas of Galileo and Gauss but avoiding calculus, students create a model that predicts whether a fly ball will clear the famous left-field wall at Fenway Park.
Geometric Reasoning about a Circle Problem
Authors: González Gloriana , DeJarnette Anna F.
Published: March 2013

An open-ended problem about a circle illustrates how problem-based instruction can enable students to develop reasoning and sense-making skills.
Elementary Algebra Connections to Precalculus
Authors: López-Boada Roberto , Daire Sandra Argüelles
Published: March 2013

Students use elementary algebra concepts to solve trigonometric and logarithmic equations and systems.
Introducing Factorials
Authors: Lassak Marshall B.
Published: March 2013

This favorite lesson guides students to see how quickly factorial numbers grow.
L’expérience de l’origine : John Glassco, traducteur de Saint-Denys Garneau
Authors: Godbout Patricia
Published: March 2013

Cet article se penche, dans une perspective sémiotique, sur la traduction anglaise, par John Glassco, d’un poème d’Hector de Saint-Denys Garneau, “Saules” (Regards et jeux dans l’espace, 1937). À partir d’une analyse très fine de ce poème proposée par Jacques Blais, la traduction de Glassco, publiée en 1975 dans les Complete Poems of Saint Denys Garneau, est examinée afin de déterminer quelle “expérience de traduction” est vécue par le traducteur.
L’actualité de Michel Tremblay traducteur et adaptateur : derrière le miroir de l’idéologie
Authors: Rao Sathya
Published: March 2013

L’objet de cet article est de mettre en lumière les présupposés sous-jacents à la lecture sociocritique de l’oeuvre de traduction et d’adaptation de Michel Tremblay afin de comprendre la valeur mais aussi les limites de cette lecture. De notre point de vue, c’est dans l’inconscient éthique de la sociocritique que résident à fois sa force et sa faiblesse. Le sort réservé à l’oeuvre de traduction et d’adaptation de Michel Tremblay en est le symptôme. Comme en témoignent ses réalisations comme traducteur et adaptateur depuis le milieu des années 1980 et le début des années 1990, Michel Tremblay n’est plus aussi ethnocentriste qu’avant. Il établit désormais une distinction très claire entre la pratique de l’adaptation, réservée en général à des pièces légères jouées sur des scènes d’été, et la pratique de la traduction qui concerne spécifiquement les “chefs-d’oeuvre”. Tandis que les adaptations portent sur des pièces françaises de France, les traductions, elles, portent sur des pièces étatsuniennes d’auteurs contemporains. Aussi différentes soient-elles, ces pratiques partagent une exigence semblable de fidélité à l’ordre et à la signification de l’original. Pour ce qui est de l’adaptation en particulier, elle devient pour Michel Tremblay un terrain de jeu où le nationalisme n’est plus l’inspiration dominante.
Enantioselective Aza‐Henry Reaction of Imines Bearing a Benzothiazole Moiety Catalyzed by a Cinchona‐Based Squaramide
Authors: He Hai‐Xiao , Yang Wen , Du Da‐Ming
Published: March 2013

An efficient enantioselective aza‐Henry reaction of nitroalkanes to imines bearing a benzothiazole moiety catalyzed by a Cinchona‐based squaramide has been developed. In the reaction of imines, the corresponding products were obtained in good to excellent yields (up to 99%) with excellent enantioselectivities (up to >99% ee) for most of the aromatic substituted imines. The imines with electron‐withdrawing groups gave better yields than those bearing electron‐donating groups in the aza‐Henry reaction. Moreover, a one‐pot three‐component enantioselective aza‐Henry reaction using 2‐aminobenzothiazoles, aldehydes, and nitromethane was also developed. Moderate to good yields and high enantioselectivities were obtained in the one‐pot cases (up to 98% ee).
The Evolution of an Amine Dehydrogenase Biocatalyst for the Asymmetric Production of Chiral Amines
Authors: Abrahamson Michael J. , Wong John W. , Bommarius Andreas S.
Published: March 2013

The reductive amination of ketones to produce chiral amines is an important transformation in the production of pharmaceutical intermediates. Therefore, industrially applicable enzymatic methods that enable the selective synthesis of chiral amines could be very useful. Using a phenylalanine dehydrogenase scaffold devoid of amine dehydrogenase activity, a robust amine dehydrogenase has been evolved with a single two‐site library allowing for the direct production of (R)‐1‐(4‐fluorophenyl)‐propyl‐2‐amine from para‐fluorophenylacetone with a kcat value of 6.85 s−1 and a KM value of 7.75 mM for the ketone substrate. This is the first example of a highly active amine dehydrogenase capable of accepting aliphatic and benzylic ketone substrates. The stereoselectivity of the evolved amine dehydrogenase was very high (>99.8% ee) showing that high selectivity of the wild‐type phenylalanine dehydrogenase was conserved in the evolution process. When paired with glucose/glucose dehydrogenase, NADH cofactor can be effficiently regenerated and the reaction driven to over 93% conversion. The broad specificity, high selectivity, and near complete conversion render this amine dehydrogenase an attractive target for further evolution toward pharmaceutical compounds and subsequent application.
Intestinal Ganglioneuromatosis: Unusual Presentation of Cowden Syndrome Resulting in Delayed Diagnosis
Authors: Vinitsky Anna , Zaleski Christina A. , Sajjad Sayed M. , McPherson Elizabeth W.
Published: March 2013

We report on a 25‐year‐old woman who presented as a teenager with macrocephaly and multiple gastrointestinal lesions including ganglioneuromas, hamartomas, lipomas, juvenile, and hyperplastic polyps in association with extra‐intestinal tumors including a retroperitoneal lipoma, storiform collagenoma, and a fibrolipomatous hamartoma. PTEN mutation analysis identified a deletion in exon 2, confirming the diagnosis of Cowden syndrome. While intestinal polyps are common among Cowden patients who undergo endoscopy, and intestinal ganglioneuromas are occasionally reported, they are not usual presenting manifestations. Intestinal ganglioneuromatosis is divided into three subgroups: (1) polypoid ganglioneuromatosis (usually few isolated ganglioneuromas), (2) generalized ganglioneuromatosis (usually associated with NF1 or MEN), and (3) ganglioneuromatous polyposis without known systemic disease, although there are several reported patients with multiple lipomas. This individual with Cowden syndrome closely resembles the latter group, thus we suggest that patients with ganglioneuromatous polyposis, especially in association with lipomas, should be evaluated for possible Cowden syndrome. © 2013 Wiley Periodicals, Inc.
Improved mechanical performances of triple super phosphate treated jute‐fabric reinforced polypropylene composites irradiated by gamma rays
Authors: Mina M. Forhad , Shohrawardy M. H. Shahid , Khan Mubarak A. , Alam A. K. M. Moshiul , Beg M. Dalour Hossen
Published: March 2013

Untreated jute‐fabric (JF) and triple‐super‐phosphate treated JF were incorporated in isotactic polypropylene (PP) to prepare sandwich composites. Untreated JF reinforced PP (UC) and treated JF reinforced PP composites (TC) were prepared using the compression molding technique at 180°C under a load of 5 tons. Both, TC and UC were irradiated by γ‐rays at various doses to produce γTC and γUC. The highest tensile‐strength (TS), flexural‐strength (FS) and Young's modulus (E) were observed for the composite loaded with 55 wt % JF and irradiated at a dose of 5.0 kGy and. The maximum increases in TS, FS, and E of γTC from UC are 17, 18, and 69%, whilst those of TC from UC are 12, 13, and 12%, respectively. Thermal degradation temperature of γTC and TC is found to increase significantly from that of UC, suggesting an improved thermal stability of the treated composites. All these findings are explained on the basis of fiber‐matrix interactions developed by the formation of physical and chemical bonds among JF and PP, as demonstrated by means of the Fourier transform infrared spectroscopy. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Thermal stability and kinetics of thermal degradation of PMVS/SiO2/GO‐C12‐hep composites
Authors: Qiu Huating , He Chengai , Zhou Lianjie , Shao Hongyun , Fan Hongjie , Mo Hong , Zhang Jun , Zhou Ninglin , Shen Jian
Published: March 2013

In this study, a series of the PMVS/SiO2/GO‐C12‐hep (polymethylvinyl siloxane, PMVS) nanocomposites of varying fillers concentration were fabricated employing blending technique. Retained tensile tests showed that tensile strength of PMVS/SiO2/GO‐C12‐hep nanocomposites improved with increasing of GO‐C12‐hep content from 0 to 0.5 wt %, but it decreased when the GO‐C12‐hep content was up to 0.8 wt %. SEM results showed that GO/C12‐hep had been dispersed into PMVS matrix, and the interfacial consistency property was very well between GO‐C12‐hep and PMVS. The degradation mechanism was also analyzed. The thermal stability and the degradation kinetics of nanocomposites had been evaluated using thermo‐gravimetric analysis (TGA) at different heating rates in flowing nitrogen. TGA curves revealed that PMVS/SiO2/GO‐C12‐hep exhibited relatively better thermal stability than PMVS/SiO2, and the degradation temperatures of PMVS/SiO2/GO‐C12‐hep increased with GO‐C12‐hep increase. The apparent activation energies (Ea) were estimated with the Flynn–Wall–Ozawa method (FWO method). The Ea of PMVS/SiO2/GO‐C12‐hep nanocomposites had relevance to their content of GO‐C12‐hep. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Dynamic DSC curing kinetic study of epoxy resin of 1,3‐bis(4‐hydroxyphenyl) prop‐2‐en‐1‐one using aromatic diamines and phthalic anhydride
Authors: Adroja Pooja P. , Ghumara Rizwan Y. , Parsania Parsotam H.
Published: March 2013

Epoxy resin of 1,3‐bis(4‐hydroxyphenyl)prop‐2‐en‐1‐one has been synthesized and studied its cure kinetics by differential scanning calorimetry at four different heating rates in nitrogen atmosphere and varying proportions of 4,4′‐diaminodiphenyl ether, 4,4′‐diaminodiphenyl sulfone and phthalic anhydride. The energy of activation (Ea) and pre‐exponential factor (A) has been determined according to Flyn‐Wall‐Ozawa method at various degrees of cure ranging from 0.1 to 0.9. The derived results are discussed in light of effect of hardeners concentrations, heating rates, degree of cure, and nature of hardeners, etc. The structure of the hardeners and their concentrations affected the cure behavior. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Using molecularly imprinted polymer for protecting functional group in organic reaction
Authors: Yang Qian , Wang Ying , Wang Guangxia , Gao Junfei , Zhao Xu , Liu Dejing , Mi Huaifeng
Published: March 2013

In this study, a novel method of selective protecting group based on molecularly imprinted polymer for regioselective organic reaction is reported. The simplicity, convenience and feasibility of this method may be illustrated by the protection of hydroxyl group at C17 or C3 of β‐estradiol in the reaction between β‐estradiol and diphenylphosphinic chloride. Polymers to protect hydroxyl group at C17 or at C3, both demonstrated excellent protection effect. In polymers imprinted with 2‐methyl‐cyclopentanol template to protect hydroxyl group at C17, the proportion of 3‐phosphate was almost as high as 100%. In molecularly imprinted polymer synthesized using 5,6,7,8‐Tetrahydro‐2‐naphthol as a template to protect hydroxyl group at C3, the proportion of 17‐phosphate reached 98.2%. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Calorimetric study of nanocomposites of multiwalled carbon nanotubes and isotactic polypropylene polymer
Authors: Kalakonda Parvathalu , Iannacchione Germano S. , Daly Michael , Georgiev Georgi Y , Cabrera Y. , Judith R. , Cebe Peggy
Published: March 2013

Modulated differential scanning calorimetry (MDSC) was used to measure the complex specific heat of the crystallization and melting transitions of nanocomposites of isotactic polypropylene (iPP) and carbon nanotubes (CNT) as function of CNT weight percent and temperature scan rate. In the last few years, great attention has been paid to the preparation of iPP/CNT nanocomposites due to their unique thermal and structural properties and potential applications. As the CNT content increases from 0 to 1 wt %, heterogeneous crystal nucleation scales with the CNT surface area. Above 1 wt %, nucleation appears to saturate with the crystallization temperature, reaching ∼8 K above that of the neat polymer. Heating scans reveal a complex, two‐step, melting process with a small specific heat peak, first observed ∼8 K below a much larger peak for the neat iPP. For iPP/CNT samples, these two features rapidly shift to higher temperatures with increasing ϕw and then plateau at ∼3 K above that in neat iPP for ϕw ≥ 1 wt %. Scan rates affect dramatically differently the neat iPP and its nanocomposites. Transition temperatures shift nonlinearly, while the total transition enthalpy diverges between cooling and heating cycles with decreasing scan rates. These results are interpreted as the CNTs acting as nucleation sites for iPP crystal formation, randomly pinning a crystal structure different than in the neat iPP and indicating complex transition dynamics. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Biodegradable polyester nanocomposites: Phase miscibility and properties
Authors: Mittal Vikas , Al Zaabi Khalid
Published: March 2013

Melt mixing of poly(butylene adipate‐co‐terephthalate) based biopolymer was performed with synthetic silica and silicate reinforcements in order to attain nanocomposites with superior properties so as to enhance the spectrum of applications of the biopolymers. The addition of 5% of fillers enhanced the modulus of the polymer by 20% and also enhanced or retained the elongation and yield stress. The thermal properties of the polymer were unaffected by the addition of fillers and did not show any decrease in the degradation temperatures occasionally observed due to the acceleration of the degradation by heat accumulated in the filler aggregates. The morphological characterization of the composites confirmed good dispersion of filler particles in the polymer matrix, however, the magnitude of large sized aggregates increased with increasing filler fraction. The addition of filler also nucleated the polymer (peak crystallization temperature increased from 15 to 30°C) but the overall melt enthalpy was a function of filler dispersion. The dynamic properties of the composites enhanced gradually, however, significantly higher properties were observed for composites with 20% filler due to the presence of aggregates. An increase of storage modulus by 400% was observed for silica composites containing 20% filler, whereas same amount of silicate enhanced the storage modulus of the polymer by 300%. The composites with lower filler fractions maintained the similar flow characteristics as pure polymer. The filler phase was observed to be miscible with polymer in all composites except those with 20% filler content. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Length‐dependent proteolytic cleavage of short oligopeptides catalyzed by matrix metalloprotease‐9
Authors: Huang Yibing , Shi Junfeng , Yuan Dan , Zhou Ning , Xu Bing
Published: March 2013

Matrix metalloproteinases (MMPs), as the enzymes to degrade extracellular matrix proteins, play a major role on cell behaviors. Among them, MMP‐9 usually catalyzes the degradation of proteins with the dominant cleavage at G/L site. Recent high‐throughput screening suggests that S/L is a new major site for the cleavage when the substrates of MMP‐9 are oligopeptides. Here we examine the cleavage sites of the N‐terminal substituted short oligopeptides as the substrates of MMP‐9. As the first example of such study of N‐substituted small peptides, our results suggest that the substitute group at the N‐terminal and the length of peptides significantly affect the position of the cleavage site on the oligopeptides, which provides a useful insight for the design of small peptide derivatives as the substrates of MMP‐9. © 2013 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 100: 790–795, 2013.
Liquid‐Solid Mass Transfer Behavior of a New Stirred‐Tank Reactor with a Packed Bed Fixed to its Wall
Authors: Mowena M. H. , Zaatout A. A. , Sedahmed G. H.
Published: March 2013

Rates of liquid‐solid mass transfer at a packed bed of Raschig rings fixed to the wall of a stirred tank were measured by a technique which involves the diffusion‐controlled dissolution of copper in acidified dichromate. Variables studied were impeller rotation speed, impeller geometry, Raschig ring diameter, bed thickness, presence of baffles, physical properties of the solution, and effect of superimposed flow. Mass transfer data for the batch reactor were correlated by a dimensionless equation. For a given set of conditions, the radial‐flow impeller was found to produce higher rates of mass transfer than the axial‐flow impeller. The presence of baffles increased the rate of mass transfer inside the bed. Applications of the suggested reactor in conducting different diffusion‐controlled liquid‐solid reactions were evaluated.
Thermodynamic Analysis for Quantifying Fuel Cell Grade H2 Production by Methanol Steam Reforming
Authors: Katiyar N. , Kumar S. , Kumar S.
Published: March 2013

Steam reforming of methanol in fixed‐bed and hybrid reactors, namely, traditional fixed‐bed reactor (FBR1), fixed‐bed reactor with H2‐selective membrane (FBR2), and fixed‐bed reactor with CO2 adsorption (FBR3) is thermodynamically analyzed. The performance of these reactors is compared in terms of quality and quantity of H2 production for fuel cell application. In FBR2 and FBR3, the contents of undesired products CO, CH4, and carbon are highly reduced.
Manipulating Catalytic Pathways: Deoxygenation of Palmitic Acid on Multifunctional Catalysts
Authors: Peng Baoxiang , Zhao Chen , Kasakov Stanislav , Foraita Sebastian , Lercher Johannes A.
Published: March 2013

The mechanism of the catalytic reduction of palmitic acid to n‐pentadecane at 260 °C in the presence of hydrogen over catalysts combining multiple functions has been explored. The reaction involves rate‐determining reduction of the carboxylic group of palmitic acid to give hexadecanal, which is catalyzed either solely by Ni or synergistically by Ni and the ZrO2 support. The latter route involves adsorption of the carboxylic acid group at an oxygen vacancy of ZrO2 and abstraction of the α‐H with elimination of O to produce the ketene, which is in turn hydrogenated to the aldehyde over Ni sites. The aldehyde is subsequently decarbonylated to n‐pentadecane on Ni. The rate of deoxygenation of palmitic acid is higher on Ni/ZrO2 than that on Ni/SiO2 or Ni/Al2O3, but is slower than that on H‐zeolite‐supported Ni. As the partial pressure of H2 is decreased, the overall deoxygenation rate decreases. In the absence of H2, ketonization catalyzed by ZrO2 is the dominant reaction. Pd/C favors direct decarboxylation (−CO2), while Pt/C and Raney Ni catalyze the direct decarbonylation pathway (−CO). The rate of deoxygenation of palmitic acid (in units of mmol moltotal metal−1 h−1) decreases in the sequence r(Pt black)≈r(Pd black)>r(Raney Ni) in the absence of H2. In situ IR spectroscopy unequivocally shows the presence of adsorbed ketene (CCO) on the surface of ZrO2 during the reaction with palmitic acid at 260 °C in the presence or absence of H2.
Flexizyme‐Mediated Genetic Reprogramming As a Tool for Noncanonical Peptide Synthesis and Drug Discovery
Authors: Passioura Toby , Suga Hiroaki
Published: March 2013

Noncanonical peptides occur frequently in Nature, and often display high bioactivity. However, the lack of tractable systems for the synthesis of diverse libraries of such peptides has thus far hampered their development as drugs. Genetic reprogramming techniques, in which noncanonical amino acids may be incorporated into peptides, have largely removed this limitation. This Concept article outlines the development of these techniques with an emphasis on drug discovery.
ChemInform Abstract: PbMnIn2S5: Synthesis, Structure, and Properties.
Authors: Yu Peng , Wu Li‐Ming , Chen Ling
Published: March 2013

The new title compound is synthesized by solid state reaction of the elements (1100 °C, 70 h) and characterized by single crystal XRD, UV/VIS diffuse reflectance spectroscopy, and magnetic measurements.
ChemInform Abstract: Enhanced Luminescence of Novel Y2Zr2O7:Dy3+ Phosphors by Li+ Co‐Doping.
Authors: Du Qingqing , Zhou Guangjun , Zhou Juan , Jia Xiao , Zhou Haifeng
Published: March 2013

Novel blue‐white Y2Zr2O7:Dy3+,Li+ phosphors are synthesized by the sol—gel combustion method starting with ZrO(Ac)2, Y(NO3)3, Dy(NO3)3, Li(NO3), NH4NO3, and citric acid (800 °C, 30 min).
ChemInform Abstract: Temperature‐Dependent Photoluminescence Properties of Deep‐Red Emitting Mn4+‐Activated Magnesium Fluorogermanate Phosphors.
Authors: Shao Qiyue , Lin Huanyun , Hu Jinlin , Dong Yan , Jiang Jianqing
Published: March 2013

Deep‐red emitting Mg28Ge7.5O38F10:xMn4+ (x = 0.001—0.015) phosphors are synthesized by solid state reaction of Mg(CO3)4·Mg (OH)2·5H2O, MgF2, GeO2, and MnCO3 using CaF2 as a flux (alumina crucible, 1300 °C, 14 h).
ChemInform Abstract: Cage‐Forming Compounds in the Ba—Rh—Ge System: From Thermoelectrics to Superconductivity.
Authors: Rogl P. , et al. et al.
Published: March 2013

Phase relations in the Ge‐rich part of the title system are studied at 700 and 750 °C.
ChemInform Abstract: Phase Equilibria in the Mo—Fe—P System at 800 °C and Structure of Ternary Phosphide (Mo1‐xFex)3P (0.10 ≤ x ≤ 0.15).
Authors: Oliynyk Anton O. , Lomnytska Yaroslava F. , Dzevenko Mariya V. , Stoyko Stanislav S. , Mar Arthur
Published: March 2013

Two new ternary phases, (Mo1‐xFex)2P (x = 0.30—0.82) and (Mo1‐xFex)3P (x = 0.10—0.15) exist in the isothermal section of the title system at 800 °C.
ChemInform Abstract: Ion Exchange Synthesis of III—V Nanocrystals.
Authors: Beberwyck Brandon J. , Alivisatos A. Paul
Published: March 2013

Cation exchange of Cd3As2 or Cd3P2 nanocrystals dissolved in tri‐n‐octylphosphine with group 13 ions (InCl3, GaCl3) yields monodisperse, crystalline III—V nanocrystals, including GaAs, InAs, GaP, and InP (270—300 °C, 15 min).
ChemInform Abstract: Synthesis, Crystal Structure, and Electronic Properties of the Tetragonal (LnILnII)3SbO3 Phases (LnI: La, Ce; LnII: Dy, Ho).
Authors: Forbes Scott , Wang Peng , Yao Jinlei , Kolodiazhnyi Taras , Mozharivskyj Yurij
Published: March 2013

The title compounds are prepared from mixtures of LnSb and Ln2O3 for each of the respective Ln in a 1:1:1:1 molar ratio (1550 °C, 10 h).
ChemInform Abstract: Chemical Adaptability: The Integration of Different Kinds of Matter into Giant Molecular Metal Oxides.
Authors: Mueller Achim , et al. et al.
Published: March 2013

The two giant wheel‐shaped molybdenum oxides of type [{Mo2}{Mo8}{Mo}]14 and [{Mo2}{Mo8}{Mo}]16 can integrate a large number of appropriate cations and anions, e.g. in form of the large “salt‐like” {M(SO4)}16 rings (M: K+, NH4+).
ChemInform Abstract: Rare‐Earth Manganese Copper Pnictides Ln2Mn3Cu9Pn7 (Pn: P, As): Quaternary Ordered Variants of the Zr2Fe12P7‐Type Structure.
Authors: Stoyko Stanislav S. , Ramachandran Krishna K. , Mullen C. Scott , Mar Arthur
Published: March 2013

The pnictides Ln2Mn3Cu9P7 (Ln: La—Nd, Sm, Gd—Dy) and Ln2Mn3Cu9As7 (Ln: La—Nd) are prepared from stoichiometric mixtures of the elements (800 °C, 14 d).
ChemInform Abstract: Multistep Organocatalysis for the Asymmetric Synthesis of Multisubstituted Aldehydes from Allylic Alcohols.
Authors: Ho Xuan‐Huong , Oh Hyun‐Ji , Jang Hye‐Young
Published: March 2013

A one‐pot oxidation/Michael addition/oxamination reaction of allylic alcohols affords the formation of multifunctionalized aldehydes with high levels of stereoselectivity under environmentally benign conditions.
ChemInform Abstract: Nickel‐Catalyzed Indium(I)‐Mediated syn‐Selective Propargylation of Aldehydes.
Authors: Hirashita Tsunehisa , Suzuki Yuuki , Tsuji Hiromitsu , Sato Yoshiki , Naito Kojiro , Araki Shuki
Published: March 2013

The Ni‐catalyzed InI‐mediated propargylation of carbonyl compounds gives the corresponding homopropargylic alcohols in high yields with syn selectivity.
ChemInform Abstract: Enhanced Efficiency of Recyclable C3‐Symmetric Cinchonine‐Squaramides in the Asymmetric Friedel—Crafts Reaction of Indoles with Alkyl Trifluoropyruvate.
Authors: Han Xin , Liu Bin , Zhou Hai‐Bing , Dong Chune
Published: March 2013

The highly efficient epicinchonine‐based squaramide (ECS) catalyst can easily be recovered and reused five times without significant loss of activity.
ChemInform Abstract: Highly Selective Barbier‐Type Propargylations and Allenylations Catalyzed by Titanocene(III).
Authors: Munoz‐Bascon Juan , Sancho‐Sanz Iris , Alvarez‐Manzaneda Enrique , Rosales Antonio , Oltra J. Enrique
Published: March 2013

The catalyst is prepared in situ from TiCl2(Cp)2 and manganese powder and regenerated by TmsCl and collidine.
ChemInform Abstract: Chain‐Walking Strategy for Organic Synthesis: Catalytic Cycloisomerization of 1,n‐Dienes.
Authors: Kochi Takuya , Hamasaki Taro , Aoyama Yuka , Kawasaki Junichi , Kakiuchi Fumitoshi
Published: March 2013

The use of chain walking provides a new method to functionalize unreactive C—H bonds.
ChemInform Abstract: Synthesis of Enaminones by Rhodium‐Catalyzed Denitrogenative Rearrangement of 1‐(N‐Sulfonyl‐1,2,3‐triazol‐4‐yl)alkanols.
Authors: Miura Tomoya , Funakoshi Yuuta , Morimoto Masao , Biyajima Tsuneaki , Murakami Masahiro
Published: March 2013

The reaction proceeds by denitrogenation of the triazol moiety generating an α‐imino Rh(II) carbenoid which undergoes 1,2‐hydride or 1,2‐alkyl migration.
ChemInform Abstract: Hydrocarbon Oxidation Catalyzed by Self‐Folded Metal‐Coordinated Cavitands.
Authors: Djernes Katherine E. , Padilla Melissa , Mettry Magi , Young Michael C. , Hooley Richard J.
Published: March 2013

A novel iron‐coordinated cavitand is prepared and successfully applied as a reusable oxidation catalyst for a variety of substrates.
ChemInform Abstract: Solvent‐Free Chemoselective Oxidation of Thioethers and Thiophenes by Mechanical Milling.
Authors: Cravotto Giancarlo , Garella Davide , Carnaroglio Diego , Gaudino Emanuela Calcio , Rosati Ornelio
Published: March 2013

A green procedure for the selective oxidation of several organosulfur compounds to the corresponding sulfones using Oxone is developed.
ChemInform Abstract: Biomimetic Oxygen Activation by MoS2/Ta3N5 Nanocomposites for Selective Aerobic Oxidation.
Authors: Gao Qingsheng , Giordano Cristina , Antonietti Markus
Published: March 2013

The novel catalyst can be applied for different substrates to give aldehydes and ketones, epoxides, sulfoxides and imines with good selectivity.
ChemInform Abstract: Direct Acyl Substitution of Carboxylic Acids: A Chemoselective O‐ to N‐Acyl Migration in the Traceless Staudinger Ligation.
Authors: Kosal Andrew D. , Wilson Erin E. , Ashfeld Brandon L.
Published: March 2013

This reaction uses chlorophosphites to synthesize amides from acids and azides.
ChemInform Abstract: NIS‐Catalyzed Reactions: Amidation of Acetophenones and Oxidative Amination of Propiophenones.
Authors: Lamani Manjunath , Prabhu Kandikere Ramaiah
Published: March 2013

The presented new method works with N‐iodosuccinimide as catalyst and tert‐butylhydroperoxide as an oxidant.
ChemInform Abstract: Efficient Synthesis of Unsymmetrical S‐(Bromodifluoromethyl)diarylsulfonium Salts for Electrophilic Bromodifluoromethylating Reagents.
Authors: Liu Guokai , Mori Satoru , Wang Xin , Noritake Shun , Tokunaga Etsuko , Shibata Norio
Published: March 2013

The title reagents are prepared from the reaction of (bromodifluoromethyl)arylsulfoxides with substituted benzenes in the presence of triflic anhydride.
ChemInform Abstract: Catalytic Functionalization of Unactivated sp3 C—H Bonds via exo‐Directing Groups: Synthesis of Chemically Differentiated 1,2‐Diols.
Authors: Ren Zhi , Mo Fanyang , Dong Guangbin
Published: March 2013

A new strategy for the title synthesis is developed.
ChemInform Abstract: Nucleophilic Fluorination of β‐Ketoester Derivatives with HBF4.
Authors: Pasceri Raffaele , Bartrum Hannah E. , Hayes Christopher J. , Moody Christopher J.
Published: March 2013

Treatment of α‐diazo‐β‐ketoester derivatives (I) with HBF4 results in nucleophilic fluorination by the usually inert and stable tetrafluoroborate anion.
ChemInform Abstract: Heteroaromatic Azo Compounds as Efficient and Recyclable Reagents for Direct Conversion of Aliphatic Alcohols into Symmetrical Disulfides.
Authors: Iranpoor Nasser , Firouzabadi Habib , Khalili Dariush
Published: March 2013

NH4 SCN is used as sulfur source in the presence of either (Ia) or (Ib).
ChemInform Abstract: Base‐Promoted Michael Reaction Concomitant with Alkylation of Cyclic‐1,3‐diones, an Efficient Approach to 2‐Substituted Vinylogous Esters.
Authors: De Subhadip , Kinthada Lakshmana K. , Bisai Alakesh
Published: March 2013

The process can be carried out under optimized conditions A) or C) in the presence of alkyl halides (III) and (VI) to produce a series of synthetically important subunits with cyclopentane or cyclohexane skeleton.
ChemInform Abstract: Organocatalyzed Intramolecular Michael Addition of Morita—Baylis—Hillman Adducts of β‐Arylnitroethylenes: An Entry to 3‐Aryl‐4‐nitrocyclohexanones.
Authors: Reddy Chada Raji , Reddy Motatipally Damoder , Haribabu Kothapalli
Published: March 2013

Reactions with L‐proline proceed with less than 20% enantiomeric excess.
ChemInform Abstract: A Novel Synthesis of Fluorine‐Containing Cyclopentenones via Pauson—Khand Reaction.
Authors: Konno Tsutomu , Kida Takumi , Tani Akinori , Ishihara Takashi
Published: March 2013

Inter‐ as well as intramolecular Pauson—Khand reactions of fluorinated alkynes furnishing the desired bicyclic products in good yield are described.
ChemInform Abstract: Cobalt‐Catalyzed Synthesis of Highly Substituted Styrene Derivatives via Arylzincation of Alkynes.
Authors: Corpet Martin , Gosmini Corinne
Published: March 2013

A series of di‐ and trisubstituted styrenes (VII) is synthesized by formation of arylzinc bromides, a carbometallation of alkynes (VI), and a subsequent hydrolysis of vinylzinc intermediates.
ChemInform Abstract: General One‐Pot Synthesis of Alkynyliodonium Salts and Alkynyl Benziodoxolones from Aryl Iodides.
Authors: Bouma Marinus J. , Olofsson Berit
Published: March 2013

This reaction uses mild conditions and yields the products in a short reaction time in high yields.
ChemInform Abstract: Nickel‐Catalyzed Decarboxylative Coupling Reaction of Alkynyl Carboxylic Acids and Allyl Acetates.
Authors: Choe Juseok , Yang Jiyoung , Park Kyungho , Palani Thiruvengadam , Lee Sunwoo
Published: March 2013

A broad spectrum of carboxylic acids is treated with allyl acetate (II).
ChemInform Abstract: Reaction of Nitroalkanes with Polyfluoroaromatic Compounds.
Authors: Vaidyanathaswamy R. , Radha K. , Dharani M. , Raguraman T. S. , Anand Rajdeep
Published: March 2013

Nitroalkanes (II) add to pentafluorobenzonitrile and methyl pentafluorobenzoate predominantly in para position under basic conditions.
ChemInform Abstract: Aromatic Nitration with Bismuth Nitrate in Ionic Liquids and in Molecular Solvents: A Comparative Study of Bi(NO3)3·5H2O/[bmim][PF6] and Bi(NO3)3·5H2O/1,2‐DCE Systems.
Authors: Jacoway Jonathan , Kumar G. G. K. S. Narayana , Laali Kenneth K.
Published: March 2013

A broad spectrum of activated arenes is investigated with the title method.
ChemInform Abstract: Synthesis of γ‐Fluoroalkylated Allylic Amine Derivatives via Palladium‐Catalyzed Overman Rearrangement.
Authors: Jiang Xin‐Yi , Chu Lingling , Wang Ruo‐Wen , Qing Feng‐Ling
Published: March 2013

The rearrangement of fluorinated allylic trichloroacetimidates produces the target compounds with excellent regio‐ and stereoselectivity.
ChemInform Abstract: New Approach to 3,3‐Difluoroallyl Alcohol.
Authors: Omote Masaaki , Miake Tatsuya , Tarui Atsushi , Sato Kazuyuki , Welch John T. , Kumadaki Itsumaro , Ando Akira
Published: March 2013

The new difluoroalkene (III) is synthesized and transformed into difluoroallyl alcohols (V) upon hydroxide‐catalyzed reaction with aldehydes.
ChemInform Abstract: Controllable Regioselective Construction of Both Functional α‐Methylene‐β‐ and ‐γ‐amino Acid Derivatives Through an Organocatalyzed Tandem Allylic Alkylation and Amination.
Authors: Pan Feng , Chen Jian‐Ming , Qin Tian‐You , Zhang Sean Xiao‐An , Liao Wei‐Wei
Published: March 2013

A controllable regioselective allylic alkylation and amination reaction is developed using α‐amino nitriles.
ChemInform Abstract: Transamidation of Primary Amides with Amines Catalyzed by Zirconocene Dichloride.
Authors: Atkinson Benjamin N. , Chhatwal A. Rosie , Lomax Helen V. , Walton James W. , Williams Jonathan M. J.
Published: March 2013

Zirconocene dichloride is found to efficiently catalyze acylation reaction with amides [cf.
ChemInform Abstract: Tandem Catalysis with a Bifunctional Site‐Isolated Lewis Acid—Broensted Base Metal—Organic Framework, NH2‐MIL‐101(Al).
Authors: Srirambalaji Renganathan , Hong Soonsang , Natarajan Ramalingam , Yoon Minyoung , Hota Raghunandan , Kim Yonghwi , Ko Young Ho , Kim Kimoon
Published: March 2013

The catalyst is effective in a tandem Meinwald rearrangement—Knoevenagel condensation and can be recycled.
ChemInform Abstract: A Novel Copper‐Catalyzed, One‐Pot Synthesis of Symmetric Organic Disulfides from Alkyl and Aryl Halides: Potassium 5‐Methyl‐1,3,4‐oxadiazole‐2‐thiolate as a Novel Sulfur Transfer Reagent.
Authors: Soleiman‐Beigi Mohammad , Mohammadi Fariba
Published: March 2013

Various title compounds can be prepared in a simple manner.
ChemInform Abstract: A Practical Synthesis and Applications of (E)‐Diphenyl‐β‐(trifluoromethyl)vinylsulfonium Triflate.
Authors: Kasai Noritaka , Maeda Ryoko , Furuno Hiroshi , Hanamoto Takeshi
Published: March 2013

An improved approach to the title compound (V) is developed.
ChemInform Abstract: Tuning the Reactivity of Difluoromethyl Sulfoximines from Electrophilic to Nucleophilic: Stereoselective Nucleophilic Difluoromethylation of Aryl Ketones.
Authors: Shen Xiao , Zhang Wei , Ni Chuanfa , Gu Yucheng , Hu Jinbo
Published: March 2013

Desulfoximination of resulting compounds (III) results in the formation of enantiomerically enriched difluoromethyl alcohols shown for (IIIa).
ChemInform Abstract: Palladium on Carbon‐Catalyzed Cross‐Coupling Using Triarylbismuths.
Authors: Monguchi Yasunari , Hattori Tomohiro , Miyamoto Yasuhiro , Yanase Takayoshi , Sawama Yoshinari , Sajiki Hironao
Published: March 2013

Three protocols for coupling of triarylbismuths with aryl halides are developed.
ChemInform Abstract: Palladium‐Catalyzed Cross‐Coupling Reaction of Aryl(trialkyl)silanes with Aryl Nitriles.
Authors: Tang Shi , Li Shu‐Hua , Yan Wen‐bin
Published: March 2013

A notable feature of the cross‐coupling is the high stability of the organosilanes and the absence of fluoride‐containing reagents.
ChemInform Abstract: Au25 Nanocluster‐Catalyzed Ullmann‐Type Homocoupling Reaction of Aryl Iodides.
Authors: Li Gao , Liu Chao , Lei Yu , Jin Rongchao
Published: March 2013

The applied catalyst can be easily recovered and reused for at least 5 cycles.
ChemInform Abstract: A Novel System for the Suzuki Cross‐Coupling Reaction Catalyzed with Light Fluorous Palladium—NHC Complex.
Authors: Yu Hong , Wan Li , Cai Chun
Published: March 2013

A novel Pd‐NHC catalyst containing fluorous tags is synthesized and successfully applied for Suzuki cross‐coupling reactions (17 examples).
ChemInform Abstract: Direct C—H Alkylation of Naphthoquinones with Amino Acids Through a Revisited Kochi—Anderson Radical Decarboxylation: Trends in Reactivity and Applications.
Authors: Naturale Guillaume , Lamblin Marc , Commandeur Claude , Felpin Francois‐Xavier , Dessolin Jean
Published: March 2013

Highly functionalized naphthoquinones are prepared by Kochi—Anderson radical decarboxylation of amino acids.
ChemInform Abstract: Synthesis of Naphthalenes via Platinum‐Catalyzed Hydroarylation of Aryl Enynes.
Authors: Kang Dongjin , Kim Jinsik , Oh Susung , Lee Phil Ho
Published: March 2013

Internal alkynyl groups (X) require electron donating substituents at the phenyl moiety for cyclization.
ChemInform Abstract: Asymmetric [3 + 2] Annulation of N‐Protected Isatins with But‐3‐yn‐2‐one Catalyzed by DIOP: Facile Creation of Enantioenriched Spiro[furan‐2,3′‐indoline]‐2′,4(5H)‐dione.
Authors: Lian Zhong , Shi Min
Published: March 2013

An organocatalytic method for preparation of the labile title compounds is presented.
ChemInform Abstract: Catalytic Enantioselective Bromolactonization of Alkenoic Acids in the Presence of Palladium Complexes.
Authors: Lee Hyun Joo , Kim Dae Young
Published: March 2013

Best results concerning the formation of optically active furanones are obtained in the presence of Pd‐complex (I).
ChemInform Abstract: One‐Pot Sequential Combination of Multi‐Component and Multi‐Catalyst: Synthesis of 5‐Aminobenzofurans from Aminophenol and Ketene Acetals.
Authors: Yang Cheng‐Wen , Bai Yue‐Xia , Zhang Ni‐Tao , Zeng Cheng‐Chu , Hu Li‐Ming , Tian Hong‐Yu
Published: March 2013

The reaction of ketene acetals (I) with p‐aminophenol tosylates in the presence of hypervalent iodine and BF3 and CuBr2 as catalysts gives benzofurans in moderate yields.
ChemInform Abstract: Design and Synthesis of Condensed Thienocoumarins by Suzuki—Miyaura Reaction/Lactonization Tandem Protocol.
Authors: Iaroshenko Viktor O. , Ali Sajid , Mkrtchyan Satenik , Gevorgyan Ashot , Babar Tariq Mahmood , Semeniuchenko Volodymyr , Hassan Zahid , Villinger Alexander , Langer Peter
Published: March 2013

Substrates of type (I) and (VII) are subjected to Suzuki—Miyaura coupling.
ChemInform Abstract: Calcium Amido‐Bisoxazoline Complexes in Asymmetric Hydroamination/Cyclization Catalysis.
Authors: Nixon Tracy D. , Ward Benjamin D.
Published: March 2013

The title catalyst is effective to afford the pyrrolidine (II) with complete conversion and 50% e.e.
ChemInform Abstract: Pd‐Catalyzed Tandem Cyclization of Ethyl Glyoxalate and Amines: Rapid Assembly of Highly Substituted Cyclic Dehydro‐α‐amino Acid Derivatives.
Authors: Luo Yueting , Lu Xiaoxia , Ye Yong , Guo Ya , Jiang Huanfeng , Zeng Wei
Published: March 2013

A possible mechanism via an α‐imino ester intermediate inserted into a hydrogen‐palladium species is described.
ChemInform Abstract: Accessing N‐Heteroarylated Indoles and Benzimidazoles from 2‐Alkynyl Cyclohexadienimines and Cyclohexadienones Through Metal‐Catalyzed Tandem Reactions.
Authors: Yang Min , Tang Jie , Fan Renhua
Published: March 2013

The protecting group of starting material (I) plays a pivotal role.
ChemInform Abstract: Merging Visible‐Light Photoredox and Lewis Acid Catalysis for the Functionalization and Arylation of Glycine Derivatives and Peptides.
Authors: Zhu Shaoqun , Rueping Magnus
Published: March 2013

The reaction shows high functional group tolerance and applies glycine esters and glycine derived dipeptides as nucleophiles.
ChemInform Abstract: A Novel Approach for Highly Regio‐ and Stereoselective Synthesis of (Z)‐3‐Methyleneisoindoline‐1‐ones in Aqueous Micellar Medium.
Authors: Sarkar Swarbhanu , Dutta Samrat , Dey Rajdip , Naskar Subhendu
Published: March 2013

The optimized conditions allow an efficient and rapid approach to the biologically important heterocyclic ring system.
ChemInform Abstract: Enantioselective Synthesis of Substituted Indoles Through Zirconium(IV)‐Catalyzed Friedel—Crafts Alkylation.
Authors: Blay Gonzalo , Fernandez Isabel , Pedro Jose R. , Vila Carlos
Published: March 2013

The method allows the introduction of a C‐3 side chain bearing a tertiary stereogenic center.
ChemInform Abstract: Straightforward Protocol for the Efficient Synthesis of Varied N1‐Acylated (Aza) Indole 2‐/3‐Alkanoic Acids and Esters: Optimization and Scale‐up.
Authors: Liedtke Andy J. , Kim Kwangho , Stec Donald F. , Sulikowski Gary A. , Marnett Lawrence J.
Published: March 2013

The indole precursors for the acylation reaction are synthesized by esterification of commercially available indole substrates or by Fischer indole synthesis.
ChemInform Abstract: Cascade Dearomatization of N‐Substituted Tryptophols via Lewis Acid‐Catalyzed Michael Reactions.
Authors: Liu Chuan , Zhang Wei , Dai Li‐Xin , You Shu‐Li
Published: March 2013

The dearomatization of tryptophols includes a Michael addition reaction and a subsequent ring‐closing iminium ion trapping, furnishing a furoindoline core with a quaternary carbon center.
ChemInform Abstract: A Tunable Route for the Synthesis of Azomethine Imines and β‐Aminocarbonyl Compounds from Alkenes.
Authors: Clavette Christian , Gan Wei , Bongers Amanda , Markiewicz Thomas , Toderian Amy B. , Gorelsky Serge I. , Beauchemin Andre M.
Published: March 2013

This method allows for modular preparation of stable, crystalline azomethines from simple alkenes and hydrazones.
ChemInform Abstract: Samarium Diiodide Mediated Highly Diastereoselective Conjugate Reduction of the α,β‐Unsaturated Ester Moiety in Heterocyclic Compounds.
Authors: Jiang Hui , Na Risong , Zhang Lei , Liu Honglei , Li Zhen , Wang Bo , Guo Hongchao
Published: March 2013

The unsaturated ester (I) is reduced completely diastereoselectively to yield the trans‐isomers (II).
ChemInform Abstract: CuI/SnCl2 Co‐Catalyzed Four‐Component Reaction of Ketones, Amines, Alkynes, and Carbon Dioxide.
Authors: Zhao Jinwu , Huang Huawen , Qi Chaorong , Jiang Huanfeng
Published: March 2013

The title tandem coupling/cycloaddition reaction is a useful tool for the synthesis of 5‐alkylene‐oxazolidinones.
ChemInform Abstract: Tempering the Reactivities of Postulated α‐Oxo Gold Carbenes Using Bidentate Ligands: Implication of Tricoordinated Gold Intermediates and the Development of an Expedient Bimolecular Assembly of 2,4‐Disubstituted Oxazoles.
Authors: Luo Yingdong , Ji Kegong , Li Yuxue , Zhang Liming
Published: March 2013

A variety of oxazole derivatives is prepared from terminal alkynes and carboxamides via a gold‐catalyzed oxidation strategy.
ChemInform Abstract: A Mild and Efficient Synthesis of 2‐Oxazolines via Transamidation—Cyclodehydrosulfurization of Thioamides with 2‐Aminoethanol.
Authors: Goud D. Raghavender , Pathak Uma
Published: March 2013

The two‐step approach renders possible the preparation of oxazole derivatives bearing either aromatic or aliphatic substituents at C‐2 and may thus find an application in synthetic and medicinal chemistry.
ChemInform Abstract: Direct Oxidative C—H Arylation of Benzoxazoles with Arylsulfonyl Hydrazides Promoted by Palladium Complexes.
Authors: Yuen On Ying , So Chau Ming , Wong Wing Tak , Kwong Fuk Yee
Published: March 2013

The oxidative protocol for C‐2 arylation of benzoxazoles (I) and (VI) utilizes readily available and easy‐to‐handle arylsulfonyl hydrazides (II) as the aryl sources.
ChemInform Abstract: One‐Pot, Four‐Component Synthesis of Novel Imidazo[2,1‐b]thiazol‐5‐amine Derivatives.
Authors: Mahdavi Mohammad , Asadi Mehdi , Saeedi Mina , Ebrahimi Mostafa , Rasouli Mohammad A. , Ranjbar Parviz R. , Foroumadi Alireza , Shafiee Abbas
Published: March 2013

Moderate to excellent yields are obtained and no undesired side reactions are observed.
ChemInform Abstract: Asymmetric Addition of Benzothiazole to N‐tert‐Butanesulfinyl Imine for the Synthesis of Chiral α‐Branched Heteroaryl Amines.
Authors: Zhang Jinlong , Yang Yuhong , Wang Mei , Lin Li , Wang Rui
Published: March 2013

Freshly generated benzothiazol‐2‐yl potassium [cf.
ChemInform Abstract: Click Chemistry Inspired Structural Modification of Azole Antifungal Agents to Synthesize Novel “Drug Like” Molecules.
Authors: Pericherla Kasiviswanadharaju , Khedar Poonam , Khungar Bharti , Kumar Anil
Published: March 2013

One‐pot azide formation followed by Cu‐catalyzed 1,3‐dipolar cycloaddition to terminal alkynes is the key step in the preparation of 32 triazoles which may have antifungal and antibacterial activity.
ChemInform Abstract: Design and Synthesis of 1H‐1,2,3‐Triazoles Derived from Econazole as Antitubercular Agents.
Authors: Kim Suhyun , Cho Sang‐Nae , Oh Taegwon , Kim Pilho
Published: March 2013

The majority of the triazole compounds is prepared by microwave‐assisted click chemistry.
ChemInform Abstract: A New Method for the Synthesis of 1,5‐Disubstituted 1,2,3‐Triazoles via Triazolium Salt Intermediates.
Authors: Koguchi Shinichi , Izawa Kazuki
Published: March 2013

The process can be conducted under cost‐effective, environmentally friendly conditions in the absence of any toxic reagents or transition‐metal catalysts.
ChemInform Abstract: Tandem Catalysis in Domino Olefin Cross‐Metathesis/Intramolecular Oxa‐Conjugate Cyclization: Concise Synthesis of 2,6‐cis‐Substituted Tetrahydropyran Derivatives.
Authors: Fuwa Haruhiko , Noguchi Takuma , Noto Kenkichi , Sasaki Makoto
Published: March 2013

Auto‐tandem as well as orthogonal‐tandem catalysis (OTC) are investigated in the preparation of the title compounds.
ChemInform Abstract: Diastereoselective Synthesis of Substituted Tetrahydropyrans by Copper(II)—Bisphosphine‐Catalyzed Olefin Migration and Prins Cyclization.
Authors: Ghosh Arun K. , Kass Jorden , Nicponski Daniel R. , Keyes Chad
Published: March 2013

A mild tandem olefination/Prins cyclization of hex‐5‐en‐1‐ols with a variety of aldehydes in the presence of phosphine ligands (I)‐(III) is developed.
ChemInform Abstract: Enantioselective Synthesis of 2‐Amino‐5,6,7,8‐tetrahydro‐5‐oxo‐4H‐chromene‐3‐carbonitriles Using Squaramide as the Catalyst.
Authors: Gao Yu , Du Da‐Ming
Published: March 2013

The tandem Michael‐addition‐cyclization reaction of cyclohexan‐1,3‐diones (I) and (IV) and benzylidenemalononitriles (II) affords title compounds (III) and (V), resp., in high yields and moderate to good enantioselectivities.
ChemInform Abstract: Zinc Oxide Nanoparticles: A Highly Efficient and Readily Recyclable Catalyst for the Synthesis of Xanthenes.
Authors: Safaei‐Ghomi Javad , Ghasemzadeh Mohammad Ali
Published: March 2013

The reaction of various aromatic aldehydes with 5,5‐dimethyl‐1,3‐cyclohexanedione (I) and 2‐naphthol (IV) proceeds under solvent‐free conditions to afford 1,8‐dioxooctahydroxanthenes (III) and 14‐aryl‐14H‐dibenzo[a,j]xanthenes (V), respectively.
ChemInform Abstract: A Method for the Synthesis of Pyridines from Aldehydes, Alkynes and NH4OAc Involving Rh‐Catalyzed Hydroacylation and N‐Annulation.
Authors: Sim Yong‐Kyun , Lee Hyejeong , Park Jung‐Woo , Kim Dong‐Su , Jun Chul‐Ho
Published: March 2013

The route to the pyridine derivatives includes the hydroacylation reaction of aldehydes with internal or terminal alkynes followed by the annulation with the symmetrical internal alkyne and a nitrogen source.
ChemInform Abstract: Synthesis and Asymmetric Hydrogenation of (3E)‐1‐Benzyl‐3‐ [(2‐oxopyridin‐1(2H)‐yl)methylidene]piperidine‐2,6‐dione.
Authors: Bisset Alexander A. , Shiibashi Akira , Desmond Jasmine L. , Dishington Allan , Jones Teyrnon , Clarkson Guy J. , Ikariya Takao , Wills Martin
Published: March 2013

Starting material (I) is prepared from N‐benzylglutarimide in three steps.
ChemInform Abstract: Isolation, Structure, Synthesis and Cytotoxicity of an Unprecedented Flupirtine Dimer.
Authors: Csuk Rene , Sommerwerk Sven , Wiese Jana , Wagner Christoph , Siewert Bianka , Kluge Ralph , Stroehl Dieter
Published: March 2013

Title compound (I), synthesized starting from 2‐amino‐6‐chloro‐3‐nitropyridine, is found to show no cytotoxicity.