bluuebunny/crossref_metadata_2025 huggingface dataset:
Vliyanie faktora migracii na stanovlenie menstrual'noj funkcii u devochek
Authors: Милушкина О. Ю. , Попов В. И. , Скоблина Н. А. , Бокарева Н. А. , Асташкевич Е. В. , Захарова А. А. , Скоблина Е. В.
Published: April 2022

Problemy migracii priobretayut masshtabnoe znachenie vo vsem mire okazyvayut vliyanie prezhde vsego na zdorov'e zhenshchin i detej. Cel'yu issledovaniya bylo ustanovit' vliyanie faktora migracii na stanovlenie menstrual'noj funkcii u devochek. S pomoshch'yu anketirovaniya v period s 2015 po 2020 g. izuchali stanovlenie menstrual'noj funkcii i vozrast menarhe u 1222 studentok 1995–2000 goda rozhdeniya razlichnoj etnicheskoj prinadlezhnosti, obuchayushchihsya na 1–2 kursah universitetov g. Moskvy. V osnovnuyu gruppu voshli 322 studentki-migrantki, v gruppu sravneniya — 900 moskvichek. Srednij vozrast menarhe u migrantok sostavil 151,35 ± 1,20 mesyaca, u moskvichek — 150,88 ± 1,06 mesyaca (p > 0,05). U uchastnic obeih grupp vozrast nastupleniya menarhe sostavil 11–15 let, chto sootvetstvuet norme. V gruppe migrantok srednij vozrast menarhe ne otlichalsya ot vozrasta nastupleniya menarhe u moskvichek i sopostavim s dannymi, poluchennymi v raznyh chastyah sveta.
Gestão (não)democrática na política educacional do estado de São Paulo - 1995-2018
Authors: Jacomini Márcia Aparecida , Perrella Cileda dos Santos Sant’Anna , Alencar Felipe , Stoco Sergio
Published: April 2022

Neste artigo analisamos programas e projetos da Secretaria da Educação do Estado de São Paulo (SEE-SP), no período de 1995 a 2018, com o objetivo de compreender a gestão educacional e suas configurações em relação a espaços e formas de participação das comunidades escolares. A metodologia adotada foi o estudo documental apoiado em referenciais teóricos da análise de políticas públicas e no diálogo com literatura relativa à gestão educacional. Entre nossas análises e interpretações, destacamos que a gestão na rede paulista de ensino foi pautada por certo distanciamento do princípio constitucional de gestão democrática da escola pública e por aproximação com pressupostos gerencialistas. Nas relações da SEE-SP com as instâncias intermediárias e as escolas predominaram orientações práticas com vistas a resultados, em detrimento da participação da comunidade no debate sobre finalidades e concepções de educação escolar. Respaldada na racionalidade neoliberal, a SEE-SP se apropriou de releituras de termos como democracia, participação e autonomia, ressignificando seus conteúdos históricos, engendrados num contexto de luta por direitos e democratização da sociedade e da escola, a fim de legitimar formas de gestão baseada no controle para maior eficiência, nos termos da Nova Gestão Pública (NGP).
Hubungan Perilaku Menggunakan Smartphone Dengan Hasil Belajar Mahasiswa Dimasa Pandemi covid-19 (Studi Kasus Di Kabupaten Labuhan Batu Selatan)
Authors: Nasution Ayu Wulan Sari , Wau Yasaratodo
Published: April 2022

Tujuan penelitian ini untuk mengetahui (1) perilaku mahasiswa menggunakan smartphone dimasa pandemi (2) tingkat pencapaian hasil belajar mahasiswa, dan (3) hubungan perilaku belajar terhadap tingkat pencapaian hasil belajar mahasiswa selama pembelajaran dengan menggunakan smartphone dimasa pandemi, Data penelitian ini dikumpulkan dengan menggunakan angket dan dokumentasi. Data penelitian di analisis dengan menggunakan teknik analisis product moment dari uji korelasional dan uji hipotesis, Tingkat pencapaian hasil belajar mahasiswa mencapai 4.0375 yang tergolong dalam kategori baik, dan (3) Terdapat hubungan perilaku belajar terhadap tingkat pencapaian hasil belajar mahasiswa selama pembelajaran dengan menggunakan smartphone dimasa pandemi mencapai 0,449 yang signifikasn pada taraf 5% persen. Koefisien determinasi mencapai 0,202 sehingga kontribusi perilaku belajar terhadap penggunaan smartphone mencapai 20,2% hubungan penggunaan smartphone terhadap perilaku dan hasil belajar mahasiswa selama pembelajaran daring dimasa pandemi.
Pandeminin birinci yılında (2020-2021) COVID-19 hastalığı geçirenlerin damgalanma algısı: Türkiye örneği
Authors: ERDOĞAN Ömer , ERSOY Mutluhan
Published: April 2022

Çalışmanın temel amacı, COVID-19 hastalığı olan ve pandeminin henüz aşı geliştirilmediği ilk yılında iyileşenlerin damgalanma deneyimlerini ve bunun depresyon ve anksiyeteyle ilişkisini araştırmaktır. Çalışma iki bölüm halinde gerçekleştirilmiş olup, birinci aşama COVID-19 hastalığı olan ve iyileşme süresi en az bir ay olan 1227 kişiye COVID-19 Stigma Ölçeği ve Hastane Kaygı ve Depresyon Ölçeği kullanılarak nicel yöntemle gerçekleştirildi. İkinci aşama, yaşam deneyimleriyle damgalanmayı ortaya çıkarmak amacıyla 50 katılımcı ile nitel görüşmelerle gerçekleştirilmiştir. Elde edilen verilerin analiz sonuçları neticesinde COVID-19 hastalığı geçirenler arasında damgalanma algısının yüksek olduğu bulunmuştur. En yüksek düzeyde damgalanma 60 yaş ve üzerindeki katılımcılar arasında görülürken, eğitim düzeyi yükseldikçe damgalanma algısının düştüğü ve iyileşme süresi arttıkça damgalanma algısının da arttığı bulunmuştur. Ayrıca damgalanma düzeyi arttıkça katılımcıların depresyon ve kaygı düzeyleri artmaktadır. Nitel görüşmelerde katılımcıların COVID-19 hastalığı geçirmeden önce, hastalık sürecinde ve iyileştikten sonra hastalığa ilişkin duygu, düşünce ve damgalanma algılarına ilişkin temalar ele alınmıştır. Hastalık sürecinde ve sonrasında en çok yaşanan duygu korku ve kaygı duyguları olurken hastalık sonrasında katılımcıların yakın sosyal çevrelerine ilişkin damgalanma yaşadıkları ve bunun onları sarstığı ifade edilmiştir.
Numerical Simulations of Inlet and Outlet Air Flow Dynamics in Healthy and Stenotic Adult Airway
Authors:   Biomechanics Unit, Department of Biomedical Engineering, University of Ibadan, Nigeria, Ayodele Oyejide J
Published: April 2022

Most numerical studies of airflow resistance in the lungs have presented flow dynamics in different stenosis tracheobronchial airway generations. However, not much is known about the airflow characteristics in conditions where stenoses are present at both the airflow inlet and out letregions, especially in truncated tracheobronchial airway models. In this study, we constructed a healthy adult airway model and two stenosed airway models made up of generation six to nine (G6-G9). Computational Fluid Dynamics (CFD) simulations were performed in all airway models to investigate the airflow characteristics. We made comparison between the inlet and outlet air flow dynamics in the healthy and stenosis models during inspiration and expiration to understand if airflow resistance was higher in the upper or lower stenosis airway.Airflow velocity and wall shear stress were greater in the upper airway (G6) for both inspiration and expiration, while wall pressure was highest in the lower airway (G9). The airflow velocities in obstructed upper tracheobronchial airways during inspiration and expiration were about 3.84 m/ sand 1.49 m/s greater than in the lower airways during same respiratory cycle, respectively. The quantitative information in this study shows that stenosis at the lower airway generation has more effect on respiratory airflow than in the upper airway generations.
A Compact Asymmetrical Triangular Truncated Polygon Super Wideband Microstrip Antenna for Wireless Communication Applications
Authors:   Assistant Professor, Department of Electronics, Govt. College (Autonomous), Kalaburagi, Karnataka, India., Ara Syeda Rafath
Published: April 2022

The rapid growth in wireless communications of today’s era requires a new generation of antennas whose operating frequency range is greater than the FCC allocated UWB (3.1-10 GHz) frequency range and also operate simultaneously for multiple communication standards in single band of frequency. Microstrip antennas technology provides these features. A ubiquitous compact asymmetrical triangle truncated polygon structure monopole fed super wideband microstrip antenna for wireless communication is proposed in this paper. The antenna uses a compact size of 50X40 mm.2 The irregular tapered truncations on patch geometry have potential effects on enlargement of operating frequency band. The antenna is designed using modified epoxy substrate material of ε= 4.2, h=1.6 mm at 3 GHz, fabricated and measured. The measured results confirm that the antenna has operating frequency band of 1.2-20.03 GHz (177.39%) with bandwidth ratio of 16:1. The antenna has stable radiation patterns and consistent gain over operating band. The time domain group delay of antenna is within 4 ns, which indicates good linear phase response. Furthermore, this proposed antenna is able to cover the DVB-H in L-band for PMP (1.45-1.49 GHz), DCS, PCS, UMTS, Bluetooth, WiMAX2500, LTE2600 and UWB bands applications.
Dual Symmetrical Slots Single Slit Partial Ground Dual Notch Rectangular Monopole Microstrip Antenna for Broadband Applications
Authors:   Assistant Professor, Department of Electronics, Govt. College (Autonomous), Kalaburagi, Karnataka, India., Ara Syeda Rafath
Published: April 2022

The worldwide wireless communication technology’s rapid growth requires broadband antennas with multiple applications simultaneously for various applications such as television, mobile phones, GPS, Wi-Fi and 4G. The design and development of Microstrip Antenna Technology fulfills these features. A simple compact Dual Symmetrical Slots Single Slit Partial Ground Dual Notch Rectangular Monopole Microstrip Antenna is designed and proposed for Broad Band Applications in this paper. The proposed antenna is fabricated on modify Epoxy substrate material of εr = 4.2, h=1.6mm at 3 GHz of dimension 50X50 mm2. The impedance bandwidth covers the range from 1.15-8.12 GHz with respective bandwidth of 150.30% for the magnitude of return loss<-10dB and VSWR<=2 with multiple resonant frequencies..The designed and proposed antenna has nearly omnidirectional radiation pattern and maximum gain at 4GHz. The Proposed antenna is most suitable for wireless communications including ISM (2.4-2.5 GHz)/ (6.765-6.795GHz), WLAN IEEE 802.11 g/a (5.15-5.35 GHz and 5.725-5.825 GHz) and C Band (4-8 GHz) applications.
Effect of amygdalin on MCF-7, MDA-MB-231 and T-47D breast cancer cells in the in vitro study
Authors: Zielińska Aleksandra , Płonka-Czerw Justyna , Nowak Agnieszka , Kuśmierz Dariusz
Published: April 2022

Introduction

Amygdalin is a chemical compound found in the seeds of many edible plants. Different studies using cancer cell cultures in vitro indicate its potential anti-cancer activity. Various types of cancer cells showed different responses to different doses of amygdalin. This may suggest many in vitro models of the activity of this compound. The aim of the study was to evaluate the effect of amygdalin on MCF-7, MDA-MB-231, and T-47D breast cancer cells and on HFF-1 normal dermal fibroblasts (control cell culture) in vitro. Cell proliferation, viability, and the changes in mRNA transcript levels of basic proteins (BAX, caspase 3 and BCL-2) involved in apoptosis were analyzed.

Materials and Methods

MCF-7, MDA-MB-231, T-47D, and HFF-1 cell lines were purchased from the ATCC. Amygdalin derived from apricot kernels was purchased from Sigma-Aldrich. CVDE, WST-1, and LDH assays were used to evaluate the effects of amygdalin on cell proliferation and viability. Molecular evaluation of gene transcription levels was performed using the RT-qPCR technique.

Results

Amygdalin causes a dose-dependent decrease in proliferation and metabolic activity of MCF-7, MDA-MB-231, and T-47D cells in the in vitro cultures. In all cell cultures amygdalin affects the mRNA levels of pro-apoptotic BAX and caspase 3 proteins and anti-apoptotic BCL-2 protein.

Conclusions

Amygdalin anti-cancer activity may be selective in relation to different cell types. It seems that examined breast cancer cells are more sensitive to amygdalin than normal cells.
TERAPIA COM LASER DE BAIXA POTÊNCIA EXERCENDO EFEITO ANTI-INFLAMATÓRIO NO PROCESSO CICATRICIAL EM EXODONTIAS DE TERCEIROS MOLARES
Authors: Sant'Ana Douat Igor , SILVA PEDRO VICTOR FONSECA , PALAZZI ALEXANDRE A
Published: April 2022

A exodontia do terceiro molar é um procedimento comum em adultos, entretanto está sujeita a algumas complicações pós-operatórias, como dores, edema, trismo e um tempo significativo de cicatrização O uso do laser de baixa potência (LLLT) aparece como uma alternativa um que promove uma melhora na resposta inflamatória e ainda tem efeito analgésico, o que pode reduzir a intensidade das complicações pós cirúrgicas. O laser de baixa potência é um tratamento promissor, de baixo custo e sem reações adversas, podendo amenizar os traumas gerados e promover um melhor pós-operatório aos pacientes. Esse estudo teve como objetivo avaliar a efetividade de ação anti-inflamatória no processo cicatricial em exodontias dos terceiros molares através de uma revisão de literatura do tema. Foram encontrados estudos nos quais procura-se avaliar os efeitos da aplicação do LLLT na redução dos níveis de dor, do edema e do trismo em pacientes submetidos a procedimento cirúrgico de exodontia de terceiros molares. A partir da análise desse material, foi possível concluir que existe a necessidade de novos estudos a respeito do tema, uma vez que, até o momento, os resultados foram inconclusivos.
Bacterias Gram negativas biodegradadoras de hidrocarburos
Authors: Rabelo Florez Roger Alberto , Márquez Gómez Marco Antonio
Published: April 2022

El objetivo principal del presente artículo es realizar una revisión bibliográfica acerca de las bacterias Gram negativas más relevantes que biodegradan hidrocarburo y revisar las técnicas de biodegradación utilizadas. Esta revisión se desarrolló en dos etapas. La primera, es un mapeo científico del tema, a través de unos parámetros de búsqueda bibliométrica registrada en Scopus, Redalyc, Scielo, Dialnet, Latindex, Nature Microbiology, entre otras y en el motor de búsquedade Google Académico, y la segunda, un análisis de red que permite identificar los documentos más relevantes. En este proceso, se encontró que los géneros bacterianos Gram negativos más representativos en biodegradar hidrocarburo son Alcanivorax spp., Bacteriovorax spp., Burkholderia spp., Chromobacterium spp., Citrobacter spp., entre otras. Estas bacterias logran biodegradar los hidrocarburos, gracias a la síntesis de los biosurfactantes, a través de las técnicas in situ y ex situ. Esta revisión es importante, pues brinda suficiente información referente a las bacterias que logran biodegradar el petróleo y sus derivados, relaciona los principales biosurfactantes usados y describe las técnicas de biodegradación.
Monocular and binocular contrast sensitivity in primary school children
Authors:   Regional Ophthalmological Dispensary, Tyumen, Russian Federation, Kоshuba Mariya A. , Petrov Sergey A. ,   Tyumen Scientific Centre SB RAS, Tyumen, Russian Federation
Published: April 2022

Purpose.. To evaluate monocular and binocular contrast sensitivity to achromatic and monochromatic colors in children of primary school age from the specific regions in the North of Russian Federation. Material and methods. 36 children of the city of Tyumen and 422 children, students at the secondary school of the village of Beloyarsk of the Priuralsky district and the village of Kharampur of the Purovsky district of the Yamalo-Nenets Autonomous District, were examined. Contrast perimetry using an atlas of test images was performed to assess the frequency-contrast characteristics (FCC) of the visual system of the examined individuals. The results of the study underwent statistical analysis using the IBM SPSS Statistics ver. 22.0 software package. Results. The monocular spatial contrast sensitivity of the children from the specific regions in the North of Russian Federation in comparison with the residents of Tyumen is significantly lower (p<0.001). The formation of the binocular visual system in children from the specific regions in the North of Russian Federation. is faster. In the area of high spatial frequencies in children, the formation of perception of blue color falls behind, which is not observed in low spatial frequencies. At the same time, in the area of medium frequencies, the perception of all monochromatic colors stays far behind, especially green. Conclusion. Normative indicators of frequency-contrast sensitivity to achromatic color of primary school children have been formed. It is established that binocular spatial contrast sensitivity in children of primary school age from the specific regions in the North of Russian Federation is formed faster than monocular spatial-frequency components, in comparison with schoolchildren of Tyumen. Key words: spatial contrast sensitivity, visual analyzer, primary school age, the specific regions in the North of Russian Federation
Finansal risklerin firma değeri üzerine etkileri: Borsa İstanbul gıda, içecek ve tütün sektöründe bir uygulama
Authors: ÖZTÜRK Mutlu Başaran , ÇELİK Mehmet Sinan , DAŞTAN Derya
Published: April 2022

Bu çalışmada firma değeri ile finansal riskler arasındaki ilişki incelenmiştir. Hem makineleşmenin hem de insan gücünün yoğun olduğu, finansal arz ve talebin fazlaca görüldüğü, Borsa İstanbul imalat sanayi sektörü içerisinde yer alan gıda, içecek ve tütün sektörü analiz edilerek sektöre ve literatüre katkı sağlanması amaçlanmıştır. Söz konusu sektördeki 23 firmanın 2010-2020 dönemini kapsayan verileri panel veri analizi yöntemiyle analiz edilmiş olup finansal risklerin firma değerine etkilerini görmek amacıyla iki model belirlenmiştir. Bu modellerde firma değerini temsil için Tobin Q ve Piyasa değeri/Defter değeri kullanılmıştır. Tobin Q modelinde firma değeri üzerinde kur riski ve likidite riski anlamlı bir etkiye sahip olurken, likidite riski ile negatif kur riskinin ise pozitif yönlü olduğu tespit edilmiştir. Piyasa değeri/Defter değeri modelinde ise kredi ve kur riski anlamlı bir etkiye sahip olup, kur riskinin negatif yönlü olduğu belirlenmiştir.
Peranan Dewan Perwakilan Rakyat Daerah Kabupaten Rokan Hulu Dalam Menjalankan Fungsi Pengawasan
Authors: Kasmawati Kasmawati , Rafizal Tengku
Published: April 2022

Penelitian ini bertujuan untuk mengetahui peranan Dewan Perwakilan Rakyat Daerah Kabupaten Rokan Hulu Dalam menjalankan Fungsi Pengawasan khususnya pengawasan Anggaran Pendapatan Belanja Daerah Kabupaten Rokan Hulu dan juga untuk mengetahui hambatan atau kendala yang dialami oleh oleh DPRD Kabupaten Rokan Hulu dalam menjalankan fungsi pengawasan tersebut. Indikator yang digunakan untuk menganalisis data dan informasi di dalam penelitian ini yaitu pengawasan penyusunan anggaran, pengawasan pelaksanaan anggaran, pengawasan perubahan anggaran dan pengawasan pelaporan anggaran. Tipe penelitian yang berlokasi di Kabupaten Rokan Hulu ini yaitu tipe penelitian deskriptif dengan metode kualitatif. Informan sebagai sumber data di dalam penelitian ini yaitu Ketua DPRD Kabupaten Rokan Hulu, Tim Anggaran Pemerintah Daerah Kabupaten Rokan Hulu dan Anggota DPRD Kabupaten Rokan Hulu dari Badan Anggaran. Penetapan informan dilakukan melalui teknik sensus untuk Ketua DPRD dan teknik purposive sampling untuk Tim Anggaran Pemerintah Daerah dan Badan Anggaran DPRD Kabupaten Rokan Hulu. Data yang digunakan dalam penelitian ini terdiri dari data primer dikumpulkan melalui teknik wawancara dan data sekunder dikumpulkan melalui teknik observasi dan dokumentasi. Teknik analisis data dalam penelitian ini bersifat induktif menggunakan model analisis data yang dikemukan oleh Miles dan Huberman yaitu reduksi data, penyajian data dan penarikan kesimpulan. Berdasarkan teknik analisis tersebut penulis menyimpulkan hasil penelitian “peranan Dewan Perwakilan Rakyat Daerah Kabupaten Rokan Hulu dalam menjalankan fungsi pengawasan Anggaran sudah terlaksana”. Meskipun demikian masih ada permasalah-permasalahan yang mutlak diperbaiki kedepannya terutama masyarakat mengharapkan profesionalisme Dewan Perwakilan Rakyat Daerah Kabupaten Rokan Hulu dan meninggalkan atribut-atribut bendara partai dalam menjalankan fungsi pengawasan anggaran. Kendala atau hambatan yang dialami oleh Dewan Perwakilan Rakyat Daerah Kabupaten Rokan Hulu hanya tidak adanya regulasi atau aturan yang jelas mengatur sejauh mana pengawasan Anggaran Pendapatan Belanja Daerah yang dilakukan oleh DPRD Kabupaten Rokan Hulu. Adapun saran yang direkomendasi dari peneliti yaitu Kepada seluruh Anggota Dewan Perwakilan Rakyat Daerah Kabupaten Rokan Hulu dalam menjalankan fungsinya khususnya fungsi pengawasan Anggaran Pendapatan Belanja Daerah lebih mementingkan kepentingan masyarakat daripada mengedepankan kepentingan politik yang berorientasi kepada kepentingan kelompok.
Peranan Komisi Pemilihan Umum Kabupaten Pelalawan Dalam Menyelenggarakan Pemilihan Umum Presiden Dan Wakil Presiden Tahun 2014
Authors: Daulay Sapran , Latief Syahrul
Published: April 2022

Penelitian ini bertujuan untuk mengetahui peranan Komisi Pemilihan Umum Daerah Kabupaten Pelalawan dalam menyelenggarakan Pemilihan Umum Presiden Dan Wakil Presiden Tahun 2014 dan juga untuk mengetahui hambatan atau kendala yang dialami oleh Komisi Pemilihan Umum Daerah Kabupaten Pelalawan dalam melaksanakan Pemilu tersebut. Indikator yang dijadikan acuan untuk mengetahui tujuan penelitian tersebut yaitu tugas pokok, kewenangan dan kewajiban berdasarkan Undang Nomor 15 Tahun 2011 tentang Penyelenggaraan Pemilihan Umum. Tipe penelitian yang berlokasi di Kabupaten Pelalawan ini menggunakan tipe deskriptif dan metode pendekatan kuantitatif yang didukung oleh metode kualitatif. Ada dua jenis data di dalam penelitian ini yaitu data primer dikumpulkan dengan teknik kuissioner dan wawancara serta data sekunder dikumpulkan dengan teknik observasi dan dokumentasi. Populasi dan sampel dalam penelitian ini bervariatif terdiri dari komisioner KPUD Kabupaten Pelalawan dan Sekretariat KPUD Kabupaten Pelalawan, peserta pemilu Panwaslu yang ditetapkan melalui teknik sensus dan purposive sampling. Analisis data dalam penelitian ini bersifat deduktif, data informasi yang dikumpulkan melalui teknik pengumpulan data akan dideskripsikan sesuai dengan kondisi faktual dilapangan secara objektif. Berdasarkan teknik analisis tersebut penulis menyimpulkan peranan Komisi Pemilihan Umum Daerah Kabupaten Pelalawan dalam menyelenggarakan Pemilihan Umum Presiden dan Wakil Presiden Tahun 2014 dinilai “cukup berperan”, akan tetapi masih terdapat beberapa hambatan yang dialami oleh KPUD Kabupaten Pelalawan seperti anggaran yang dimililki oleh Komisi Pemilihan Umum Kabupaten Pelalawan sangat minin, lemahnya Sumber Daya Manusia di Kabupaten Pelalawan yang mengakibatkan munculnya sifat apatis, lemahnya Sumber Daya Manusia penyelenggara Pemilihan Umum Presiden dan Wakil Presiden terutama pada PPS dan KPPS sehingga mengakibatkan terjadinya kesalahan dalam proses pemungutan suara dan luasnya wilayah Kabupaten Pelalawan sehingga beberapa Kecamatan dan Desa memiliki jarah tempuh yang jauh dan tidak didukung dengan sarana dan prasarana yang memadai. Sedangkan rekomendasi dari peneliti yang perlu dipertimbangkan terutama bagi masyarakat Kabupaten Pelalawan agar menanamkan sifat partisipatif dan Kepada Komisi Pemilihan Umum Kabupaten Pelalawan dan Komisi Pemilihan Umum Daerah lainnya agar lebih selektif dan objektif dalam merekrut anggota PPK, PPS dan KPPS
Implementasi Peraturan Bupati Rokan Hulu Nomor 39 Tahun 2011 Tentang Pelimpahan Sebagian Kewenangan Bupati Rokan Hulu Kepada Camat Untuk Melaksanakan Urusan Pemerintahan Daerah
Authors: Suryawan Iwan , Rauf Rahyunir
Published: April 2022

Penelitian ini mendiskripsikan hasil penelitian tentang implementasi peraturan Bupati Rokan Hulu Nomor 39 Tahun 2011 Tentang Pelimpahan Sebagian Kewenangan Bupati Rokan Hulu kepada Camat untuk melaksanakan urusan pemerintahan daerah. Hal yang melatar belakangi penelitian ini adalah masih sedikitnya masyarakat yang melakukan pengurusan perizinan baik izin bangunan maupun izin usaha di jalan lingkungan dan jalan lokal di kecamatan Ujung Batu, sehingga tidak sesuai dengan pesatnya pertumbuhan bangunan dan pertumbuhan ekonomi dibandingkan dengan masyarakat yang mengurus perizinan, Selain itu terdapatnya pegawai yang mengambil alih tugas yang bukan bidangnya, Masih kurangnya Pemerintah Kecamatan Ujung Batu dalam melakukan sosialisasi tentang pengurusan perizinan di Kecamatan Ujung Batu. Kurangnya sosialisasi terkait dengan masalah anggaran serta tidak terlihat adanya standar pelayanan yang jelas. Metode penelitian ini adalah metode penelitian kualitatif dengan menghubungkan tujuan penelitian dengan masalah dan gejala yang terjadi. Metode pengumpulan data dilakukan dengan wawancara, observasi dan dokumentasi. Data yang diperoleh selanjutnya dikumpulkan dan disajikan untuk diambil kesimpulan. Penelitian ini dilaksanakan di Kecamatan Ujung Batu Kabupaten Rokan Hulu. Berdasarkan hasil penelitian dan teknis analisis yang penulis gunakan maka dapat disimpulkan bahwa Implementasi Peraturan Bupati Rokan Hulu Nomor 39 Tahun 2011 Tentang Pelimpahan sebagian Kewenangan Bupati Rokan Hulu Kepada Camat untuk melaksanakan urusan pemerintahan kurang terimplementasi. Rekomendasi ini perlu dipertimbangkan untuk menjadi masukan kepada Bupati Rokan Hulu dan Camat Ujung Batu agar melakukan upaya sosialisasi mengenai pengurusan perizinan di jalan lingkungan dan jalan lokal serta memberikan sanksi yang tegas kepada masyarakat yang membangun Rumah, ruko dan jenis usaha yang tidak memiliki izin.
Umwelteinflüsse auf Werkstoffe
Authors: Faller Markus , Richner Peter
Published: April 2022

Environmental effects on metallic materials are investigated by the combination of a field exposure programme and laboratory exposures. The exposure sites were chosen at locations of the Swiss National Air Pollution Monitoring Network (NABEL) in different regions of Switzerland. Using material loss and the type of corrosion products formed after four years in conjunction with the local climate data, the relevant parameters for the corrosion of the materials investigated can be deduced. Further insights into the mechanism are gained by laboratory exposures carried out in humid air containing single air pollutants (SO2, NO, NO2, O3, laboratory air). Sulfur dioxide and the time of wetness are playing the most important factors for the corrosion of unalloyed carbon steel, zinc, and hot-dip galvanized steel. In the case of copper, ozone has to be considered in addition. The analysis of the mass of corrosion products retained on the surface of zinc samples showed that in the case of unsheltered specimens ca. 60% of the corroded zinc was lost while for the sheltered samples 90% of the corroded zinc remained on the surface of the specimen. The results of the study can be used for the evalutation of the air protection measures.
Lessons from Nature
Authors: Nakanishi Koji , Berova Nina
Published: April 2022

Terrestrial and marine animals, plants, insects, and microorganisms produce a large variety of compounds for the organism's development, daily survival, self-defence, symbiosis, sexual attraction, etc. Certain of these compounds are discussed here, with emphasis not only on their
isolation and structure determination, but also on the question as to why they are active. This requires a multidisciplinary approach, for a better understanding of life's processes and nature's mysteries.
Neurotoxins from Snake Venom
Authors: Tu Anthony T.
Published: April 2022

Found within snake venoms are a variety of toxic and nontoxic proteins. The effects of snake venoms depend on all of the components of that venom. However, the lethal effects are usually related to the most potent toxins found within the venom; the two most toxic proteins found in snake
venom are neuro- and cardiotoxins. This article reviews a variety of neurotoxins found in snake venom. The range of neurotoxins present in snake venom is varied and includes: peripheral and noncentral, presynaptic, postsynaptic, potassium-channel inhibiting, muscarinic transmission inhibiting,
and anticholinesterase types.
Combining Equational Theories Sharing Non-Collapse-Free Constructors
Authors:   Aachen University of Technology, Baader Franz , Tinelli Cesare
Published: April 2022

In a previous work, we describe a method to combine decision procedures for the word problem for theories sharing constructors. One of the requirements of our combination method is that constructors be collapse-free. This paper removes that requirement by modifying the method so that it applies to non-collapse-free constructors as well. This broadens the scope of our combi- nation results considerably, for example in the direction of equational theories corresponding to modal logics.
A Tableau Algorithm for the Clique Guarded Fragment
Authors:   Mathematische Grundlagender Informatik, RWTH Aachen, Hirsch Colin , Tobies Stephan ,   RWTH Aachen, LuFg Theoretical Computer Science
Published: April 2022

Aus der Einleitung: „The Guarded Fragment of first-order logic, introduced by Andréka, van Benthem, and Németi, has been a succesful attempt to transfer many good properties of modal, temporal, and description logics to a larger fragment of predicate logic. Among these are decidability, the finite modal property, invariance under an appropriate variant of bisimulation, and other nice modal theoretic properties. ...”
Computing Most Specific Concepts in Description Logics with Existential Restrictions
Authors:   Institut für Informatik und Praktische Mathematik Christian-Albrechts-Universität zu Kiel, Küsters Ralf , Molitor Ralf ,   IT Research and Development Group Swiss Life Zurich
Published: April 2022

Computing the most specific concept (msc) is an inference task that can be used to support the 'bottom-up' construction of knowledge bases for KR systems based on description logics. For description logics that allow for number restrictions or existential restrictions, the msc need not exist, though. Previous work on this problem has concentrated on description logics that allow for universal value restrictions and number restrictions, but not for existential restrictions. The main new contribution of this paper is the treatment of description logics with existential restrictions. More precisely, we show that, for the description logic ALE (which allows for conjunction, universal value restrictions, existential restrictions, negation of atomic concepts) the msc of an ABox-individual only exists in case of acyclic ABoxes. For cyclic ABoxes, we show how to compute an approximation of the msc. Our approach for computing the (approximation of the) msc is based on representing concept descriptions by certain trees and ABoxes by certain graphs, and then characterizing instance relationships by homomorphisms from trees into graphs. The msc/approximation operation then mainly corresponds to unraveling the graphs into trees and translating them back into concept descriptions.
A Database Approach for Modeling and Querying Video Data
Authors:   Aachen University of Technology, Decleir Cyril , Hacid Mohand-Saïd , Kouloumdjian Jacques
Published: April 2022

Indexing video data is essential for providing content based access. In this paper, we consider how database technology can offer an integrated framework for modeling and querying video data. As many concerns in video (e.g., modeling and querying) are also found in databases, databases provide an interesting angle to attack many of the problems. From a video applications perspective, database systems provide a nice basis for future video systems. More generally, database research will provide solutions to many video issues even if these are partial or fragmented. From a database perspective, video applications provide beautiful challenges. Next generation database systems will need to provide support for multimedia data (e.g., image, video, audio). These data types require new techniques for their management (i.e., storing, modeling, querying, etc.). Hence new solutions are significant. This paper develops a data model and a rule-based query language for video content based indexing and retrieval. The data model is designed around the object and constraint paradigms. A video sequence is split into a set of fragments. Each fragment can be analyzed to extract the information (symbolic descriptions) of interest that can be put into a database. This database can then be searched to find information of interest. Two types of information are considered: (1) the entities (objects) of interest in the domain of a video sequence, (2) video frames which contain these entities. To represent these information, our data model allows facts as well as objects and constraints. We present a declarative, rule-based, constraint query language that can be used to infer relationships about information represented in the model. The language has a clear declarative and operational semantics. This work is a major revision and a consolidation of [12, 13].
Rewriting Concepts Using Terminologies
Authors:   Aachen University of Technology, Baader Franz , Molitor Ralf
Published: April 2022

In this work we consider the inference problem of computing (minimal) rewritings of concept descriptions using defined concepts from a terminology. We introduce a general framework for this problem. For the small description logic FL₀, which provides us with conjunction and value restrictions, we show that the decision problem induced by the minimal rewriting problem is NP-complete.
Optimisation of Terminological Reasoning
Authors:   Aachen University of Technology, Horrocks Ian , Tobies Stephan
Published: April 2022

An extended abstract of this report was submitted to the Seventh International Conference on Principles of Knowledge Representation and Reasoning (KR2000). When reasoning in description, modal or temporal logics it is often useful to consider axioms representing universal truths in the domain of discourse. Reasoning with respect to an arbitrary set of axioms is hard, even for relatively inexpressive logics, and it is essential to deal with such axioms in an efficient manner if implemented systems are to be effective in real applications. This is particularly relevant to Description Logics, where subsumption reasoning with respect to a terminology is a fundamental problem. Two optimisation techniques that have proved to be particularly effective in dealing with terminologies are lazy unfolding and absorption. In this paper we seek to improve our theoretical understanding of these important techniques. We define a formal framework that allows the techniques to be precisely described, establish conditions under which they can be safely applied, and prove that, provided these conditions are respected, subsumption testing algorithms will still function correctly. These results are used to show that the procedures used in the FaCT system are correct and, moreover, to show how effiency an be significantly improved, while still retaining the guarantee of correctness, by relaxing the safety conditions for absorption.
Inventory of the lands of Western Yakutia disturbed by geological exploration according to remote sensing data
Authors: ЛЕГОСТАЕВА Я.Б. , ЖУРАВЛЕВ А.И. , ПОПОВ В.Ф. , ШАДРИНОВА О.В. , НОЕВ Д.С.
Published: April 2022

Западная Якутия славится своими недровыми богатствами. Трудно переоценить роль геологов-разведчиков разных поколений, внесших свой вклад в его изучение. Сегодня в Западной Якутии наиболее интенсивно развиваются алмазодобывающая и нефтегазовая промышленность. Добычу полезного ископаемого предваряют региональный, поисковый и разведочный стадии геологоразведочных работ. При этом современная система экологического нормирования, используемая при оценках влияния геологоразведочных работ на окружающую среду, недостаточна и несовершенна, особенно для масштабных геологоразведочных работ на нефть и газ. Требуется разработка специальных природоохранных нормативов воздействия на окружающую среду при реализации геологических проектов с учетом различных географо-климатических и горно-геологических условий, на основе изучения эколого-геохимических факторов и оценке устойчивости компонентов ландшафта конкретной территории к техногенному воздействию.Проведены исследования по оценке геоэкологической безопасности геологоразведочных работ на территории Западной Якутии. Составлен реестр нарушенных участков, выявлены и рассчитаны площади нарушенных вследствие геологоразведочных работ земель. Проведена адаптация методики дешифрирования космических снимков высокого разрешения для мелкомасштабных линейных объектов. Выявлена масштабность геологоразведочного техногенеза, которая имеет значительную региональную распространенность, при этом имеется перспектива развития на всю территорию Западной Якутии, включая шельф моря Лаптевых. Это будут сотни тысяч километров просек, миллион квадратных километров, превращенных в сеть геофизических профилей, шириной порядка 10 м. Следует отметить, что последствия такого техногенеза сегодня не известны. Как будет реагировать криолитозона и подземная и поверхностная гидросфера, какова будет реакция газогидратов, заключенных в недрах? Такой масштаб работ уже сегодня может влиять на климатические процессы регионального масштаба, возможно, они в какой-то мере виноваты в засушливых годах, идущих один за другим в Центральной Якутии. Выполненная работа позволяет осознать масштаб техногенного воздействия, искать пути решения, формировать линию «зеленой» геологоразведки в целях сохранения окружающей нас среды.
FEATURES OF DEVELOPMENT, NUTRITION, LOADING SHOVELS AND MEASURES OF STRUGGLE IN THE CONDITIONS OF THE ARAL REGION
Authors: Шамуратова Н.Г. , Норкулов А.Н.
Published: April 2022

В статье представлено опрыскивание люцерников инсектицидами суми-альфа (0,6 л/га) или цимбуш (0,3 л/га) обеспечивает получение высокой (91–93%) биологической эффективности против подгрызающих совок.

The article presents the spraying of alfalfa with insecticides sumi-alpha (0.6 l / ha) or cymbush (0.3 l / ha) provides high (91–93%) biological effectiveness against gnawing moths.
N-Metallocenyl Ynamides: Preparation, Oxidative Functionaliza-tion and Synthesis of an ansa[3]-Ferrocenylamide
Authors: Mahe Capucine , Blacque Olivier , Gasser Gilles , Gandon Vincent , Cariou Kevin
Published: April 2022

The discovery of new organometallic frameworks is of high interest for the field of bioorganometallic chemistry. In this work, to the best of our knowledge, we report the first synthesis of various N-metallocenyl ynamides and some of their reactivity. In particular, the use of hypervalent iodine(III) reagents triggered an unprecedented oxidative cyclization leading to ansa[3]-ferrocenyl compounds while the same reaction conditions with the ruthenocene analogues led to an acyclic acetoxy-adduct. The mechanism of the cyclization has been studied by means of DFT calculations, showing that it proceeds through a Concerted Iodination Deprotonation (CID) step. This study not only expands further the chemistry of ynamides but also opens up new avenues in bioorganometallic chemistry by providing an exclusive access to an original ferrocephane moiety to be employed in this research field.
Diversity Oriented Clicking: Synthesis of beta-Substituted Alkenyl Sulfonyl Fluorides as Covalent Human Neutrophil Elastase Inhibitors
Authors: Cheng Yunfei , Li Gencheng , Smedley Christopher J. , Giel Marie-Claire , Kitamura Seiya , Woehl Jordan L. , Bianco Giulia , Forli Stefano , Homer Joshua A. , Cappiello John R. , Wolan Dennis W. , Moses John E. , Sharpless K. Barry
Published: April 2022

Diversity Oriented Clicking (DOC) is a discovery method geared towards the rapid synthesis of functional libraries. It combines the best attributes of both classical and modern click chemistries. DOC strategies center upon the chemical diversification of core “SuFExable” hubs – exemplified by 2-Substituted-Alkynyl-1-Sulfonyl Fluorides (SASFs) – enabling the modular assembly of compounds through multiple reaction pathways. We report here a range of stereoselective Michael-type addition pathways from SASF hubs including reactions with secondary amines, carboxylates, 1H-1,2,3-triazole, and halides. These high yielding conjugate addition pathways deliver unprecedented beta-substituted alkenyl sulfonyl fluorides as single isomers with minimal purification, greatly enriching the repertoire of DOC and holding true to the fundamentals of modular click chemistry. Further, we demonstrate the biological function – another key objective of click chemistry – of this new scaffold as covalent inhibitors of human neutrophil elastase (hNE). The ease of diversification of SASFs through click pathways, enabling rapid access to biologically important molecules, further validates Diversity Oriented Clicking as an effective and robust method for lead discovery.
Selectivity and Intrinsic Activity of Functionalized Cu Surfaces: Can the CO2 Reduction Reaction be Improved on Cu?
Authors: Christensen Oliver , Zhao Siqi , Sun Zhaozong , Bagger Alexander , Rosas-Hernández Alonso , Vang Lauritsen Jeppe , Uttrup Pedersen Steen , Daasbjerg Kim , Rossmeisl Jan
Published: April 2022

Cu is the only monometallic catalyst known for producing valuable multi-carbon-based products, such as ethylene and ethanol, from the CO2 reduction reaction (CO2RR). One approach to optimize the activity and selectivity of the metal Cu catalyst is to functionalize the Cu electrode with a molecular modifier. We investigate from a data standpoint whether any reported functionalized Cu catalyst improves the intrinsic activity and/or multi-carbon product selectivity compared to the performance of bare Cu foil and the best single crystal Cu facets. Our analysis shows that the reported increases in activity are due to increased surface roughness and disappear once normalizing with respect to electrochemical surface area. The intrinsic activity generally falls below that of bare Cu foil, both for total and product-specific current, which we attribute to non-selective blocking of active sites by the modifier on the surface. Instead, we show that the modifier allows for easier diffusion of CO2 compared to H2O to the surface, leading to greater selectivity for CO2RR and C2+ products. As such, there is currently not a catalyst for CO2RR that intrinsically outperforms bare Cu.
Extracting Structural Motifs from Pair Distribution Function Data of Nanostructures using Explainable Machine Learning
Authors: Anker Andy S. , Kjær Emil T. S. , Juelsholt Mikkel , Lindahl Christiansen Troels , Skjærvø Susanne Linn , Jørgensen Mads Ry Vogel , Kantor Innokenty , Sørensen Daniel Risskov , Billinge Simon J. L. , Selvan Raghavendra , Jensen Kirsten Marie Ørnsbjerg
Published: April 2022

Characterization of material structure with X-ray or neutron scattering using e.g. Pair Distribution Function (PDF) analysis most often rely on refining a structure model against an experimental dataset. However, identifying a suitable model is often a bottleneck. Recently, new automated approaches have made it possible to test thousands of models for each dataset, but these methods are computationally expensive, and analysing the output, i.e., extracting structural information from the resulting fits in a meaningful way is challenging. Our Machine Learning based Motif Extractor (ML-MotEx) trains an ML algorithm on thousands of fits, and uses SHAP (SHapley Additive exPlanation) values to identify which model features are important for the fit quality. We use the method for 4 different chemical systems including disordered nanomaterials and clusters. ML-MotEx opens for a new type of modelling where each feature in a model is assigned an importance value for the fit quality based on explainable ML.
Highly Diastereo- and Branched-Selective Rearrangement of Substituted N-Alloc-N-Allyl Ynamides via Pd-Auto-Tandem Catalysis
Authors: Cook Matthew , Jackson Oliver , Stankevich Ksenia
Published: April 2022

An auto-tandem catalytic, branched-selective rearrangement of substituted N-alloc-N-allyl ynamides was developed. This reaction provides ready access to complex quaternary nitrile products with vinylogous stereocenters in excellent diastereoselectivity, including the formation of contiguous all-carbon quaternary centers. The stereochemical outcome is determined via a Pd(0) catalyzed dipolar ketenimine aza-Claisen rearrangement inside a deep cleft on the catalyst. Computational studies exemplify the key role ligand geometry plays throughout the reaction coordinate in this previously unreported mechanism. This study provides new reaction pathways for both π-allyl and sigmatropic rearrangements.
Funcionamento familiar e a sua relação com a regulação emocional na adolescência
Authors: Medeiros Raquel , Relva Inês , Fernandes Otília
Published: April 2022

A forma como uma família funciona pode influenciar o modo como os adolescentes regulam as suas próprias emoções. Assim, este estudo visa analisar a relação entre o funcionamento familiar e a regulação emocional na adolescência. A amostra foi constituída por 625 adolescentes de ambos os sexos (entre os 15 e os 20 anos de idade). Os resultados revelaram que os adolescentes do ensino profissional e do sexo masculino percecionam pior comunicação na família e maiores dificuldades familiares, e, genericamente, os adolescentes do sexo masculino percecionam maiores dificuldades na regulação emocional do que os adolescentes do sexo feminino. Os resultados sugerem, ainda, um efeito preditor entre o funcionamento familiar e a regulação emocional na adolescência. Parece, pois, necessário trabalhar com as famílias e adolescentes, com o objetivo de incrementar competências, e deste modo melhorar a sua regulação emocional. Este estudo assume relevância, pelas potenciais implicações para a intervenção com adolescentes e suas famílias.
Effect of Free Surface Based on Submergence Depth of Underwater Vehicle
Authors: Youn Taek-Geun , Kim Min-Jae , Kim Moon-Chan , Kang Jin-Gu
Published: April 2022

This paper presents the minimum submergence depth of an underwater vehicle that can remove the effect of free surface on the resistance of the underwater vehicle. The total resistance of the underwater vehicle in fully submerged modes comprises only viscous pressure and friction resistances, and no wave resistance should be present, based on the free surface effect. In a model test performed in this study, the resistance is measured in the range of 2 to 10 kn (1.03–5.14 m/s) under depth conditions of 850 mm (2.6D) and 1250 mm (3.8D), respectively, and the residual resistance coefficients are compared. Subsequently, resistance analysis is performed via computational fluid dynamics (CFD) simulation to investigate the free surface effect based on various submergence depths. First, the numerical analysis results in the absence of free surface conditions and the model test results are compared to show the tendency of the resistance coefficients and the reliability of the CFD simulation results. Subsequently, numerical analysis results of submergence depth presented in a reference paper are compared with the model test results. These two sets of results confirm that the resistance increased due to the free surface effect as the high speed and depth approach the free surface. Therefore, to identify a fully submerged depth that is not affected by the free surface effect, case studies for various depths are conducted via numerical analysis, and a correlation for the fully submerged depth based on the Froude number of an underwater vehicle is derived.
Neurophobia: causes and methods to reduce it
Authors: Jukna Š. , Mameniškienė Rūta
Published: April 2022

Neurophobia can be defined as a fear of neurosciences and clinical neurology experienced by students, residents, and doctors due to their inability to apply their knowledge of basic sciences to clinical situations. The concept of neurophobia was first mentioned by Ralph Jozefowicz in 1994, but only in 2002 neurophobia was scientifically proven. Since then, research around the world has shown that medical students rate neurology as the most complex discipline, have the lowest level of confidence in their neurological knowledge, and feel the least confident in their competencies when assessing patients with neurological problems. Neurophobia is thought to be caused by: too short a training period, poor study quality, complex neuroanatomy, difficult neurological examination, neurology training by a non-practicing neurologist, and the stigma that neurologists are dissatisfied with their profession. Medical students and doctors find neurology difficult. Understanding the causes of neurophobia and promoting neurophilia would not only increase the willingness of medical students to choose the profession of neurologist, but also improve the care and treatment of patients with neurological diseases.