bluuebunny/crossref_metadata_2025 huggingface dataset:
Current state of surgical treatment for patients with tubular breast type II (a literature review)
Authors: Kostenko A. A. , Galych S. P. , Dabizha O. Yu. , Samko K. A. , Borovyk D. V.
Published: April 2021

The aim of the study – to analyze the modern literature, summarize current approaches to surgical treatment of tubular breast type II and identify the causes of poor results.
Tubular breast deformity relates to congenital connective tissue malformations, occurs in puberty and causes a great deal of psychological discomfort to women. The majority of authors note that type II of tubular breast is the most common among patients referred to clinic for a surgical correction.
In fact, the correction of this type of malformation is a reconstructive procedure associated with a number of challenges. The goal of such operation is not only to increase a volume of the breast lower pole, but also to cover the implant maximally using soft tissues to achieve a normal lower pole contour.
To date, a number of surgical techniques have been proposed to address these problems, such as C. Puckett and M. Concannon (1990), L. Ribeiro (1998), E. Muti (1996), A. Mandrekas (2003) and their modern modifications. Fat grafting techniques in treatment of tubular breast are also getting popular, but all have some drawbacks.
Conclusions. A high level of complications and the absence of a universal method for correction of tubular breast type II are preconditions for improving the surgical technique to correct this pathology.
The value of perioperative ECG in patients with complicated forms of coronary artery disease
Authors: Dzakhoieva L. S. , Gogayeva O. K. , Rudenko A. V. , Lazoryshynets V. V.
Published: April 2021

The aim: to analyze the informativeness and features of the perioperative electrocardiogram dynamics in complicated forms of coronary artery disease (CAD).
Material and methods: retrospective ECG analysis of 100 randomized high-risk patients with complicated forms of CAD who underwent surgery in the National M. Amosov Institute of Cardiovascular Surgery Affiliated to National Academy of Medical Sciences of Ukraine from 2009 to 2019. All the patients included in the study were classified as high-risk group for complications and mortality and had an average risk of 8.60 % (from 5.02 % to 39.38 %) according to the EuroSCORE II scale.
Results. Postinfarction left ventricular aneurysm (ALV) was localized in the anteroseptal region of the left ventricle (LV) in 94 (94 %) cases, and posterior-basal LV aneurysm (PBALV) was diagnosed in 6 (6 %) patients. Mitral insufficiency (MI) was detected in 8 (8.5 %) patients with anterior ALV and in 2 (33.3 %) cases of PBALV. Tricuspid valve insufficiency (TI) was diagnosed in 4 (4.2 %) patients with anterior ALV, and postinfarction defect of the interventricular septum (VSD) was verified in 2 (33.3 %) patients with PBALV. Diagnostics of anteroseptal ALV using ECG is highly accurate, the specificity of the method is 94 %, and the sensitivity is 95.6 %. ECG interpretation after surgery presents with certain difficulties, since nonspecific changes of the terminal part of the ventricular complex often occur that being interpreted correctly determine further treatment tactics. Positive ECG dynamics was detected in 66 (66 %) patients in the form of improved intraventricular conduction and the appearance of the R wave in leads I, avL, V2-V6, a lack of dynamics – in 11 (11 %), as a rule, in patients with complete left bundle branch block (LBBB), dry pericarditis of II–III stage was diagnosed in 23 (23 %) patients.
Conclusions. ECG retains its importance and remains an informative and available method in modern cardiology. The correct ECG interpretation before surgery helps to assess the initial severity of the condition and timely correct the therapy and management tactics in the early postoperative period.
Efektywność komunikowania a efektywność porozumiewania się
Authors: Domachowski Waldemar
Published: April 2021

This article aims at describing the evidence for the efficacy of communication. The author differentiates effectiveness and efficacy of communication, as well as communication per se and communication with each other. He argues that there can be no discussion about the efficacy of communication without establishing its effectiveness. A communication process can be ineffective either when there is no recipient of the communicate or when the message is not received due to, for example, a noise. Even though the effectiveness can be measured using a nominal scale, the efficacy requires at least an ordinal scale. The author bases his conclusions on the theory of communication models, intentionality and, proposed by him, “a constant species”.
Język agresji u dzieci z rodzin dysfunkcyjnych
Authors: Sileńska Aleksandra , Szpunar Kamila
Published: April 2021

Language of aggression, which is the subject of this article, is closely linked with the concept of aggression. Aggression is understood as any form of behaviour directed at causing damage or causing injury to another living creature. The article presents a pilot study about aggressive language and behaviour of children from dysfunctional families. Sample consisted of 12 children, aged 7 through 12, from dysfunctional families. Competent referees made observation of children’s language and behaviour using observation questionnaire. The observation took part during their activities at a community day care social centre. The result showed that referees agreed that the children from the study sample often used aggressive language and behave aggressively. There is a lack of this kind of studies.
Budget constrained interactive search for multiple targets
Authors: Zhu Xuliang , Huang Xin , Choi Byron , Jiang Jiaxin , Zou Zhaonian , Xu Jianliang
Published: April 2021

Interactive graph search leverages human intelligence to categorize target labels in a hierarchy, which is useful for image classification, product categorization, and database search. However, many existing interactive graph search studies aim at identifying a single target optimally, and suffer from the limitations of asking too many questions and not being able to handle multiple targets.

To address these two limitations, in this paper, we study a new problem of budget constrained interactive graph search for multiple targets called kBM-IGS problem. Specifically, given a set of multiple targets
T
in a hierarchy and two parameters
k
and
b
, the goal is to identify a
k
-sized set of selections
S
, such that the closeness between selections
S
and targets
T
is as small as possible, by asking at most a budget of
b
questions. We theoretically analyze the updating rules and design a penalty function to capture the closeness between selections and targets. To tackle the kBM-IGS problem, we develop a novel framework to ask questions using the best vertex with the largest expected gain, which provides a balanced trade-off between target probability and benefit gain. Based on the kBM-IGS framework, we first propose an efficient algorithm STBIS to handle the SingleTarget problem, which is a special case of kBM-IGS. Then, we propose a dynamic programming based method kBM-DP to tackle the MultipleTargets problem. To further improve efficiency, we propose two heuristic but efficient algorithms, kBM-Topk and kBM-DP+. Experiments on large real-world datasets with ground-truths verify both the effectiveness and efficiency of our algorithms.
On the string matching with
k
differences in DNA databases
Authors: Chen Yangjun , Nguyen Hoang Hai
Published: April 2021

In this paper, we discuss an efficient and effective index mechanism for the string matching with
k
differences, by which we will find all the substrings of a target string
y
of length
n
that align with a pattern string
x
of length
m
with not more than
k
insertions, deletions, and mismatches. A typical application is the searching of a DNA database, where the size of a genome sequence in the database is much larger than that of a pattern. For example,
n
is often on the order of millions or billions while
m
is just a hundred or a thousand. The main idea of our method is to transform
y
to a BWT-array as an index, denoted as
BWT
(
y
), and search
x
against it. The time complexity of our method is bounded by O(
k
· |
T
|), where
T
is a tree structure dynamically generated during a search of
BWT
(
y
). The average value of |
T
| is bounded by O(|Σ|

2
k

), where Σ is an alphabet from which we take symbols to make up target and pattern strings. This time complexity is better than previous strategies when
k
≤ O(log
|Σ|
n
). The general working process consists of two steps. In the first step,
x
is decomposed into a series of
l
small subpatterns, and
BWT
(
y
) is utilized to speedup the process to figure out all the occurrences of such subpatterns with ⌊
k/l
⌋ differences. In the second step, all the found occurrences in the first step will be rechecked to see whether they really match
x
, but with
k
differences. Extensive experiments have been conducted, which show that our method for this problem is promising.
Dealer
Authors: Liu Jinfei , Lou Jian , Liu Junxu , Xiong Li , Pei Jian , Sun Jimeng
Published: April 2021

Data-driven machine learning has become ubiquitous. A marketplace for machine learning models connects data owners and model buyers, and can dramatically facilitate data-driven machine learning applications. In this paper, we take a formal data marketplace perspective and propose the first en
D
-to-end mod
e
l m
a
rketp
l
ace with diff
e
rential p
r
ivacy (
Dealer
) towards answering the following questions:
How to formulate data owners' compensation functions and model buyers' price functions? How can the broker determine prices for a set of models to maximize the revenue with arbitrage-free guarantee, and train a set of models with maximum Shapley coverage given a manufacturing budget to remain competitive
? For the former, we propose compensation function for each data owner based on Shapley value and privacy sensitivity, and price function for each model buyer based on Shapley coverage sensitivity and noise sensitivity. Both privacy sensitivity and noise sensitivity are measured by the level of differential privacy. For the latter, we formulate two optimization problems for model pricing and model training, and propose efficient dynamic programming algorithms. Experiment results on the real chess dataset and synthetic datasets justify the design of
Dealer
and verify the efficiency and effectiveness of the proposed algorithms.
Teseo and the analysis of structural dynamic graphs
Authors: De Leo Dean , Boncz Peter
Published: April 2021

We present Teseo, a new system for the storage and analysis of dynamic structural graphs in main-memory and the addition of transactional support. Teseo introduces a novel design based on sparse arrays, large arrays interleaved with gaps, and a fat tree, where the graph is ultimately stored. Our design contrasts with early systems for the analysis of dynamic graphs, which often lack transactional support and are anchored to a vertex table as a primary index. We claim that the vertex table implies several constraints, often neglected, that can actually impair the generality, the robustness and extension opportunities of these systems. We compare Teseo with other dynamic graph systems, showing a high resilience to workload and input changes, while achieving comparable, if not superior, throughputs in updates and latencies in raw scans.
Heracles
Authors: Wang Zhiqi , Xue Jin , Shao Zili
Published: April 2021

Performance-monitoring timeseries systems such as Prometheus and InfluxDB play a critical role in assuring reliability and operationally. These systems commonly adopt a column-oriented storage model, by which timeseries samples from different time-series are separated, and all samples (with both numeric values and timestamps) in one timeseries are grouped into chunks and stored together. As a group of timeseries are often collected from the same source with the same timestamps, managing timestamps and metrics in a group manner provides more opportunities for query and insertion optimization but posts new challenges as well. Besides, for performance monitoring systems, to support better compression and efficient queries for most recent data that are most likely accessed by users, huge volumes of data are first cached in memory and then periodically flushed to disks. Periodic data flushing incurs high IO overhead, and simply discarding flushed data, which can still serve queries, not only is a waste but also brings huge memory reclamation cost. In this paper, we propose Heracles which integrates two techniques - (1) a new storage model, which enables efficient queries on compressed data by utilizing the shared timestamp column to easily locate corresponding metric values; (2) a novel two-level epoch-based memory manager, which allows the system to gradually flush and reclaim in-memory data while unreclaimed data can still serve queries. Heracles is implemented as a standalone module that can be easily integrated into existing performance monitoring timeseries systems. We have implemented a fully functional prototype with Heracles based on Prometheus tsdb, a representative open-source performance monitoring system, and conducted extensive experiments with real and synthetic timeseries data. Experimental results show that, compared with Prometheus, Heracles can improve the insertion throughput by 171%, and reduce the query latency and space usage by 32% and 30%, respectively, on average. Besides, to compare with other state-of-the-art storage techniques, we have integrated LevelDB (for LSM-tree-based structure) and Parquet (for column stores) into Prometheus tsdb, respectively, and experimental results show Heracles outperform these two integrations. We have released the open-source code of Heracles for public access.
On analyzing graphs with motif-paths
Authors: Li Xiaodong , Cheng Reynold , Chang Kevin Chen-Chuan , Shan Caihua , Ma Chenhao , Cao Hongtai
Published: April 2021

Path-based solutions have been shown to be useful for various graph analysis tasks, such as link prediction and graph clustering. However, they are no longer adequate for handling complex and gigantic graphs. Recently,
motif-based analysis
has attracted a lot of attention. A motif, or a small graph with a few nodes, is often considered as a fundamental unit of a graph. Motif-based analysis captures high-order structure between nodes, and performs better than traditional "edge-based" solutions. In this paper, we study
motif-path
, which is conceptually a concatenation of one or more motif instances. We examine how motif-paths can be used in three path-based mining tasks, namely link prediction, local graph clustering and node ranking. We further address the situation when two graph nodes are not connected through a motif-path, and develop a novel defragmentation method to enhance it. Experimental results on real graph datasets demonstrate the use of motif-paths and defragmentation techniques improves graph analysis effectiveness.
KLL
±
approximate quantile sketches over dynamic datasets
Authors: Zhao Fuheng , Maiyya Sujaya , Wiener Ryan , Agrawal Divyakant , Abbadi Amr El
Published: April 2021

Recently the long standing problem of optimal construction of quantile sketches was resolved by
K
arnin,
L
ang, and
L
iberty using the KLL sketch (FOCS 2016). The algorithm for KLL is restricted to online insert operations and no delete operations. For many real-world applications, it is necessary to support delete operations. When the data set is updated dynamically, i.e., when data elements are inserted and deleted, the quantile sketch should reflect the changes. In this paper, we propose
KLL
±
, the first quantile approximation algorithm to operate in the
bounded deletion
model to account for both inserts and deletes in a given data stream. KLL
±
extends the functionality of KLL sketches to support arbitrary updates with small space overhead. The space bound for KLL
±
is [EQUATION], where ∈ and δ are constants that determine precision and failure probability, and α bounds the number of deletions with respect to insert operations. The experimental evaluation of KLL
±
highlights that with minimal space overhead, KLL
±
achieves comparable accuracy in quantile approximation to KLL.
A New Hybrid Wavelet-Neural Network Approach for Forecasting Electricity
Authors: BOUBAKER Heni , BEN AMOR SOUHIR , Rezgui Hichem
Published: April 2021

This study investigates the performance of a novel neural network technique in the problem of price forecasting. To improve the prediction accuracy using each model’s unique features, this research proposes a hybrid approach that combines the -factor GARMA process, empirical wavelet transform and the local linear wavelet neural network (LLWNN) methods, to form the GARMA-WLLWNN process. In order to verify the validity of the model and the algorithm, the performance of the proposed model is evaluated using data from Polish electricity markets, and it is compared with the dual generalized long memory -factor GARMA-G-GARCH model and the individual WLLWNN. The empirical results demonstrated the proposed hybrid model can achieve a better predicting performance and prove that is the most suitable electricity market forecasting technique.
The Dynamic Effects of Renewable Energy on Economic Growth : The Case of China
Authors: Almozaini Majed
Published: April 2021

This paper estimates the possible effects of renewable energy consumption on the economic growth of the major renewable energy- consuming country in the world. The country has taken the lead in renewable energy in the past decade, so the paper chooses the top renewable energy-consuming country China to explain the growth process between 1990 and 2019. Using time-series analysis techniques, this study Estimation and testing result from the different cointegration methods in the context of China. The results confirm the evidence of long-run dynamics between economic growth, and traditional and energy-related inputs. Findings from long-run output elasticities indicate that renewable energy consumption has a significant positive impact on economic output. The findings suggest that governments, energy planners, international cooperation agencies and associated bodies must act together in increasing renewable energy investment for low carbon growth in most of these economies.
TORC2/3-mediated DUSP1 upregulation is essential for human decidualization
Authors: Xu Chunfang , Zhao Weijie , Huang Xixi , Jiang Zhuxuan , Liu Lu , Cui Liyuan , Li Xinyi , Li Dajin , Du Meirong
Published: April 2021

Decidualization is the functional transformation process of endometrium in response to ovarian steroids dedicated to support embryo development. Defective decidualization is closely associated with various pregnancy complications such as recurrent miscarriage (RM). Dual specificity MAPK phosphatases (MKPs) are a family of phosphatases specifically regulating mitogen-activated protein kinase (MAPK) signaling with dual specificity for threonine and tyrosine. Here, using RNA-seq,we found that dual specificity phosphatase 1 (DUSP1) expression was prominently elevated among the MKP family members in db-cAMP treated primary human endometrial stromal cells (ESCs). We verified that its induction by db-cAMP in ESCs was in a dose- and time-dependent manner and that primary human decidual stromal cells (DSCs) present higher expression of DUSP1 than ESCs. A protein kinase A (PKA) inhibitor H-89 abolished its induction in ESCs, but not ESI-09, an EPAC1/2 inhibitor. Knock-down of TORC2/3 but not CREB by siRNA in ESCs diminished its induction by db-cAMP. Furthermore, knock-down of DUSP1, as well as TORC2/3 by siRNA caused abnormal activation of JNK during db-cAMP induction in ESCs, accompanied by decreased IGFBP1 expression, an ESC decidualization indicator, which could be fully rescued by a JNK inhibitor SP600125. In addition, Western blot showed that DUSP1 expression was reduced in the DSCs of patients with RM, along with JNK overactivation and decreased IGFBP1 expression. In conclusion, our results demonstrated that TORC2/3-mediated DUSP1 upregulation in response to the cAMP/PKA signaling safeguards IGFBP1 expression via restraining JNK activity, indicating its involvement in ESC decidualization, and that aberrant expression of DUSP1 in DSCs might engage in the pathogenesis of RM.
Kupiškėnų monoftongų priegaidės (Audicinis tyrinėjimas)
Authors: Eidukaitienė Eugenija Vytautė
Published: April 2021

Rytų aukštaičių monoftongų priegaidės klausimu jau yra susikaupę nemaža prieštaringų minčių. todėl pribrendo reikalas jį patikrinti kruopštesniais audiciniais ir instrumentiniais eksperimentais.Rytų aukštaičių monoftongų priegaides skyrė, tyrinėjo ir aprašė A. Baranauskas, K. Jaunius, K. Būga. Jie nė kiek neabejojo tų priegaidžių realumu ir aiškumu. Nuomonės, kad priegaides skiria visos lietuvių kalbos tarmės, laikėsi P. Skardžius, J. Gerulis, iš esmės ir A. Salys, nors jis bene pirmasis prabilo apie tam tikrą rytų aukštaičių priegaidžių neryškumą. Tačiau pamažu ši nuomonė pakeičiama kita: pokario metais beveik stichiškai įsigali mintis, kad rytų aukštaičiai ilgųjų monoftongų priegaides yra suniveliavę, t. y. jas taria praktiškai visai vienodas. Ta pažiūra buvo labai paranki daugeliui mokytojų, nes nereikalavo jokių specialių pastangų ir lengvai pateisino jų pačių daromas klaidas, todėl greitai prigijo ir aukštaičių rytiečių mokyklose, ir dialektologiniuose tyrinėjimuose. Įsigalėjus požiūriui, kad rytiečių ilgųjų balsių i·, u·, e·, o· ir dvibalsių ie, uo “senosios” priegaidės nebeskiriamos, imta kirčiuotą ilgąjį skiemenį kalbinėje literatūroje žymėti viduriniu priegaidės ženklu. Tai, žinoma, dar labiau įtvirtino “niveliacijos teoriją”, nes tyrinėtojams leido lengvai užrašinėti rytiečių tekstą, nė nekreipiant dėmesio į kirčiuotų ilgųjų balsių niuansus. Pagaliau buvo padaryta ir visikai kategoriška išvada: “...šiaurės rytų Lietuvos dalyje [...] jokių priegaidžių čia nėra”. Kiek nuosaikesnis yra “Lietuvių dialektologijos” autorius, kuris atsargiai nurodo, kad “tvirtapradė priegaidė labai supanašėjo su tvirtagale”.Pastaruoju metu vėl pradėta daugiau domėtis rytų aukštaičių tarmės priegaidėmis: rašomi šia tema diplominiai darbai, skaitomi moksliniai pranešimai ir t. t. Daugely tų darbų vėl keliama ir įrodinėjama mintis, kad vis dėlto monoftongų priegaidės rytiečių šnektose nėra visai sutapusios. Apie tai rašyta ir lingvistiniuose žurnaluose.Šiame darbe, remiantis kupiškėnų tarmės faktų audicine analize, norima patikrinti, kuri iš tų dviejų hipotezių yra teisingesnė.
Žmogaus išorinių savybių apibūdinimas kai kuriais zoomorfizmais
Authors: Rosinienė Gražina
Published: April 2021

Šiame straipsnyje aprašomos miško žvėris reiškiančių žodžių perkeltinės reikšmės, vartojamos žmogaus išorei apibūdinti lietuvių kalboje; be to, parodoma, kaip tos reikšmės realizuojamos kalboje ir kokį atspalvį (menkinamąjį ar maloninį) jos turi. Pirmajame skyrelyje nagrinėjami zoomorfizmai, apibūdinantys apskritai žmogaus išvaizdą ir atskiras jo kūno dalis, pvz.: plaukus, akis ir pan. Antrajame skyrelyje aptariami zoomorfizmai, apibūdinantys žmogaus sudėjimą (kompleksiją), t. y. ūgį ir svorį. Minėtosios reikšmės analizuojamos, pateikiant visus modelius, kurie užfiksuoti “Lietuvių kalbos žodyno” I–IX t., X–XI tomų rankraščiuose ir kartotekoje (raidės S-Z), be to, grožinėje literatūroje.
К вопросу о семантическом содержании видов русского глагола
Authors: Галнайтите Э.
Published: April 2021

В последние десятилетия в русском языкознании сосуществуют две точки зрения при определении общих значений видов глагола. Однако это не означает, что все разногласия вокруг этой проблемы уже разрешены. Вопрос о том, что является основным различием между глаголами совершенного и несовершенного видов, остается одним из самых спорных вопросов в аспектологии.Согласно мнению большинства исследователей, положительно характеризуется лишь совершенный вид; несовершенный вид – это немаркированный член видовой оппозиции, так как он не обладает значением, свойственным совершенному виду. Поэтому, когда речь идет о семантическом содержании видов, по сути, имеется в виду грамматическое значение сов. вида. В данной статье дается краткий обзор некоторых последних работ, посвященных проблеме видов, а также делается попытка рассмотреть некоторые стороны упомянутого вопроса в несколько другом аспекте.
SELECTION OF TOLERANT WHEAT VARIETIES DURING THE GERMINATION PHASE
Authors: MOUHSSINE FATINE , Ech-Cheddadi Sara , Ouhaddach Moussa , Goumi Younes El , El yacoubi Houda , Rochdi Atmane
Published: April 2021

In Morocco, wheat is an indispensable and important crop for the population. Its production in areas affected by salinity is a major problem. The salinity-tolerant variety factor is one of the ways to ensure good productivity. Germination is considered a critical step in the plant's development cycle. Consequently, this study aimed to screen the tolerance to salinity of five varieties of wheat at the germination stage. The experiment was carried out under laboratory conditions, using five concentrations of NaCl 0, 3, 6, 9, and 12g/L. Several parameters were used: the germination rate, the corrected germination, the reduction percentage in germination, the final percentage of germination, the mean daily germination, the germination index, the vigor index of germination, the germination rate index, the velocity coefficient, the average time of germination, the length of coleoptiles and roots. Intraspecific variability of wheat toward salinity was relatively large. The daily germination rate, the final germination, the reduction percentage in germination, the germination rate index, and the mean daily germination proved to be the most appropriate criteria to study the salinity effect on seed germination. Also, an equal hierarchy of sensitivity/tolerance levels during the subsequent development of the coleoptiles and the roots has been adversely affected by increasing salinity. All these parameters describing the germination wheat seeds showed that Rajae variety performs better (relatively tolerant) while; Radia and Kanz varieties are the most affected by salt stress. The results showed that the salt reduces germination by delaying its speed except for Rajae and Amal.
MOLECULAR ANALYSIS OF A PUTATIVE EN/SPM-RELATED TRANSPOSON PROTEIN IN BRASSICA JUNCEA
Authors: Yassein Ahmed , Eid Gehad , Hemeda Nada , El Feky Zaki
Published: April 2021

Open reading frame (ORF) of Putative En/Spm transposon in Brassica potentially helps to understand the relationship between various eukaryotic transposable elements. The current study was initially conducted to isolate and analyze the putative En/Spm-related transposon gene from Brassica juncea. PCR products (750 bp) from B. juncea (accession PI 649105 and PI 271442) were cloned, sequenced, and analyzed. Results of BLAST showed identical sequences between two accessions with 100% similarity. The amplified DNA transposon and conserved domain compared to the GenBank database to evaluate the genetic diversity relationships. Sequence of this putative transposon gene from B. juncae was a 98% similar to B. rapa subsp pekinensis at the nucleotide level, and 94% with the En/Spm-related transposon protein of B. oleracea at the amino acid level. Conserved domain architecture was related to transposase_21_pfam0299 and transposase family tnp2 and had a relationship with space outside the cell structure and/or to space outside the plasma membrane.
MILK ANALYSIS BY FLOW CYTOMETRY TO IDENTIFY SUBCLINICAL UDDER INFECTION
Authors: Mazurenko Victoria , Molozhava O. , Sobko І. , Kolibo D.
Published: April 2021

Subclinical mastitis in cows is an expensive disease that is difficult to detect without special tests for diagnosis. The number of somatic cells (SCC) in milk is used as an important indicator of the udder health since SCC are parts of the innate immune system and are involved in protecting the mammary glands from infection. Our study aimed to determine whether it is possible to detect subclinical mastitis in cattle at an early stage using a simple and fast flow cytometry method, and then to suggest the main cell populations on the point sections of flow cytometry and, together with that, to develop a method for predicting mastitis. As a result of the microscopic method, three samples with contagious infection were identified. It was shown that milk from cows with mastitis contained populations of cells accompanying inflammation (suspected macrophages, granulocytes) that can be detected using frontal light scattering (FS) and right signals (SS).
PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY OF SLOVAK VARIETAL WINES OF MUSCAT TYPE
Authors: Čeryová Natália , Bajčan Daniel , Lidiková Judita , Musilová Janette , Šnirc Marek , Jančo Ivona , Franková Hana , Bláhová Mária
Published: April 2021

Grapes and wine are important sources of antioxidants in human diet. Phenolic substances contained in grapevine berries belong to an important group of natural substances that get into wine in the process of wine making. Polyphenols and flavonoids are primarily accountable for the colour and taste of the wine, they affect the perception of bitterness and acerbity. They also have antioxidant properties, thus have a positive effect on human health. Health benefits of polyphenolic substances from wine may be associated with a wide range of biological processes. Thanks to the development of modern analytical methods, wine is constantly being researched in terms of the content of antioxidants, and its importance to human health. Sixteen Slovak white wines of Muscat type produced in different geographical regions were analysed in this study. The object of this work was to determine total polyphenol content and total flavonoid content, and to evaluate antioxidant effects of quality wines of Muscat varieties produced in Slovakia. Antioxidant activity, total polyphenol content, and total flavonoid content of particular wines is described in the study. Studied characteristics were analysed by UV-VIS spectrometry method. Muscat wines showed weak to high antioxidant activity, ranging from 25.2% inhibition of DPPH to 67.7% inhibition of DPPH. Average antioxidant activity was 38.7% inhibition of DPPH. Total polyphenol content in the Muscat type varietal wines varied from 262.1 GAE.L-1 to 568.3 GAE.L-1. Average total polyphenol content was 382.13 GAE.L-1. The content of total flavonoids in Muscat type varietal wines ranged from 24.8 mg CE.L-1 to 169.1 mg CE.L-1. Average total flavonoid content was 100.5 mg CE.L-1.
In vino veritas. Wine and its Context in the Uyghur Society: an Insight to the Economic Life of the Silk Roads
Authors: Vér Márton
Published: April 2021

This paper deals with viticulture, viniculture and their social context in the Turfan region from the West Uyghur period (9th–12th cc.) up to the end of the Mongol period (14th century). A comparative analysis of narrative sources alongside documents written in Old Uyghur (ca. 10th–14th cc.) and Middle Mongolian (13th–14th cc.) sheds new light on the interplay between wine production, commerce and state interest, demonstrating that wine was already one of the most important staple products of the Turfan region in the earlier period and a commodity of primary interest to the Mongol Empire. The article illuminates Old Uyghur sources’ depictions of ortok partners, stressing how their peculiarities diﬀer from the better-known ortoq partnerships employed by the Mongol aristocracy, and highlights growing interest among the nobility in wine production and the institutionalization of vinicultural assets during the Mongol period. The author argues that these processes mirror changes in transportation and Eurasian interregional contacts under Mongol rule. Finally, despite the scattered and fragmentary nature of these sources on local economy and society, the author argues that they prompt a reevaluation of trade along the Silk Roads.
Revisión de una inscripción de Septimio Severo en el Balneario Romano de Caldas de Montbui (Vallés Oriental, Barcelona)
Authors: Sánchez-Alguacil Jesús
Published: April 2021

Este artículo ofrece una interpretación de un epígrafe en el núcleo de Caldas de Montbui (IRC I, 41) que podría mostrar un acto de lealtad entre este asentamiento y el emperador Septimio Severo. Para dar apoyo a esta hipótesis, el artículo analiza la actividad de Septimio Severo en el noreste de Hispania Citerior Tarraconensis y, en relación a ella, la presencia de esta dedicación en Caldas de Montbui.
Conversa com o editor
Authors: Chaves de Souza Vitor , Higuet Etienne Alfred
Published: April 2021

Caras leitoras e caros leitores, a nossa revista não morreu. Apesar do grande atraso, nesses tempos de pandemia, conseguimos oferecer um número bem consistente para concluir o ano de 2020. O presente número apresenta 10 artigos, quase todos relacionados com o pensamento de Paul Tillich.
Crítica e formação: a interpretação do protestantismo por Paul Tillich
Authors: Danz, Tradução: Etienne Alfred Higuet Christian
Published: April 2021

Podemos distinguir três estágios no desenvolvimento da compreensão tillichiana do protestantismo: primeiro, a construção de um princípio teológico na Teologia sistemática de 1913; segundo, a interpretação do protestantismo depois da Primeira Guerra Mundial; e terceiro, a formulação do protestantismo como crítica e estruturação no fim dos anos vinte, quando o protestantismo é construído por Tillich como uma religião autorreflexiva, que incorpora todavia a redescoberta da tradição profética realizada pela Reforma. O texto mostra que o terceiro estágio se mantém até nos últimos textos de Tillich.
Teologia e cultura: tensões em tempos pandêmicos
Authors: De Melo Odenicio Junior Marques
Published: April 2021

RESUMOO objetivo da presente discussão é construir um diálogo de alguns tópicos do pensamento de Paul Tillich e alguns desafios teológicos que têm surgido em nosso atual contexto de pandemia, com questões relacionadas à ressignificação da fé e seus atravessamentos culturais.Tal contexto ocasionado pela pandemia da covid-19 traz um novo lugar para que a teologia de Tillich (ou alguns eixos) nos aponte horizontes de compreensão para a fé e suas potencialidades, quando as limitações dos empreendimentos humanos têm aparecido sem pedir licença, sobretudo com imagens fortes que a mídia vem trazendo, as covas com sepultamentos coletivos, com isso um medo da morte e perguntas sobre o sentido da vida pulsam, convocando os teólogos a ofertarem suas contribuições na tentativa de trazer alívio às múltiplas dimensões do sofrimento humano.
Collinearity isn't a disease that needs curing
Authors: Vanhove Jan
Published: April 2021

Once they have learnt about the effects of collinearity on the output of multiple regression models, researchers may unduly worry about these and resort to (sometimes dubious) modelling techniques to mitigate them. I argue that, to the extent that problems occur in the presence of collinearity, they are not caused by it but rather by common mental shortcuts that researchers take when interpreting statistical models and that can also lead them astray in the absence of collinearity. Moreover, I illustrate that common strategies for dealing with collinearity only sidestep the perceived problem by biasing parameter estimates, reformulating the model in such a way that it maps onto different research questions, or both. I conclude that collinearity in itself is not a problem and that researchers should be aware of what their approaches for addressing it actually achieve.
The Problems of Mediation Procedure in Civil Proceedings
Authors:   Donetsk Academy of Internal Affairs of the Ministry of Internal Affairs of the Donetsk People’s Republic, Derbisheva Olga
Published: April 2021

Introduction: the paper discusses the actual problems of the legislation of the mediation procedure, as well as the existing obstacles to the development of civil practice in the application and improvement of the alternative dispute resolution procedure. The purpose of the paper is to study the problems of the institution of the mediation procedure, to understand the concept of conciliation procedures for further improving and forming recommendations for the efficiency of justice. In the process of consideration, the doctrinal problems, the formal-legal approach and the formallegal, systematic methods were used. Results: the study of the legislation allows us to identify the provisions that need to be improved and changed for a more active and complete implementation of the mediation procedure in public relations. Conclusions: the author identifies the ways to resolve such difficulties at the pre-trial stage to optimize the judicial burden. The dispute resolution procedure with the participation of a mediator is considered from the position of an effective alternative to judicial proceedings. It has a legislative consolidation, but there are a number of regulatory gaps that require solving a large number of tasks to improve them. It is necessary to carry out the extensive work in order to integrate this procedure into the civil and arbitration process: to develop a strategy for the systematic development of the mediation institute, to inform the public, the business community and practicing lawyers in order to introduce the procedure and develop the practice of application, and also, to solve the problem with the professional training of mediators and to encourage them to engage in this type of activity on a professional basis.
International Integration Organizations and the Sovereignty of Member States
Authors:   Financial University under the Government of the Russian Federation, Galushko Dmitry
Published: April 2021

Introduction: the paper analyzes the characteristics which are typical for the international integration organizations, generalized both at the doctrinal and normative levels, touches on the phenomenon of supranationality as a modern legal reality of international integration, and considers the basis for the transfer of sovereign powers by states, as the only bearers of sovereignty, to the international integration organizations. The purpose of the research is to study and analyze some aspects of the interaction between the international integration organizations and member states in the context of the supranational characteristics of such organizations. Methods: as part of the study, both the general scientific methods of cognition and the private legal methods (formal-legal, comparativelegal) were used. Results: the paper proves that the international integration organizations are a new reality of the modern system of international relations and international law. The author has established that such organizations have a number of characteristic features that distinguish them from the classical international intergovernmental organizations. As one of these main features, the author analyzes the phenomenon of supranationality, which is largely due to the voluntary transfer of their sovereign powers by the member states in favor of the integration associations. Conclusions: in contrast to the participation of states in the international organizations, the membership in the integration associations leads to the restriction of their sovereign rights by states, some of which are transferred to such an association. At the same time, such a transfer cannot be interpreted as their loss or the loss of their sovereign identity, because it’s the state who is the bearer of sovereignty. We are talking about the voluntary transfer of certain sovereign powers that can be revoked at any time, which can be seen in the example of the process of Britain’s exit from the European Union – Brexit.
Quality of kids’ meals in fast-food restaurants: the nutritional content is not enough for an informed choice
Authors: PINTO Daniela Costa , VIEGAS Cláudia Alexandra Colaço Lourenço , ROCHA Ada Margarida Correia Nunes da
Published: April 2021

ABSTRACT Objective Eating out in restaurants is a common family behavior, but it has been persistently associated with unbalanced nutrient intakes, contributing to create and reinforce unhealthy food habits among children. The purpose of this study was to evaluate the kids’ meals from three common well-known restaurant chains in Portugal. Methods The nutritional composition (total fat, carbohydrates, protein, and sodium content) of the menus was analyzed bromatologicaly, and food portions were also examined. The assessment was carried out according to the European Food Safety Authority recommendations. Results Analyses of the menus from the two points of view revealed that the evaluations for macronutrients and food portions may return contradictory results. Protein, carbohydrates, and fats are compliant with the requirements for most of the meals. The analysis from the food portion perspective exceeds the requirements for the meat, fish, and eggs groups, as well as for fats and oils. Fruits, vegetables, and pulses are not present in the menus. Despite the balance associated with the macronutrients, the salt content exceeds the recommendations for most of the meals. Conclusions Popular fast-food chain restaurants have already adapted to comply with nutritional recommendations, whilst neglecting important recommended foods such as fruit, pulses, and vegetables. This study points not only to the need of investing in the improvement of the offerings, but also to the importance of fighting the tendency to reduce the perception of food quality to its nutritional content, leading consumers to believe that the meals offered are balanced when they are not.
Dicamba residues in sprayers: Phytotoxicity on non-dicamba tolerant soybean
Authors: Marques Matheus G. , Cunha João Paulo A. R. da , Alves Guilherme S.
Published: April 2021

ABSTRACT This study aimed to evaluate the dicamba residue after cleanout procedures in sprayers with different tank materials (fiberglass and polyethylene) and its effects on the symptomology of non-dicamba tolerant (DT) soybean. The experiment consisted of spraying rinsates collected during a cleanout of boom sprayers on non-DT soybean at the V3 stage. Once the dicamba solution was mixed in the sprayer tank and sprayed, four rinses were made, and for each rinse, a sample was collected. The dicamba residue analyses in each rinse solution were conducted in a completely randomized design with three replicates in a 2 × 4 factorial scheme, corresponding to two sprayer tank materials (fiberglass and polyethylene) and four rinses, using High-Performance Liquid Chromatograph (HPLC). The evaluation of the potential risk of injury on non-DT soybean caused by dicamba residue was conducted in a randomized block design with four replicates and a 2 × 4 + 1 factorial scheme, corresponding to two types of sprayer tank material (fiberglass and polyethylene), four rinses, and control (without application). The dicamba was effectively removed using at least three rinses regardless of spray tank material. Fiberglass tank sprayer retained more residue in the first rinsate, but similar to polyethylene tank sprayer in the following rinses. Plant height was reduced by spraying rinsates collected from the first rinse regardless of tank material. In contrast, visual estimation of injury and reduced yield were observed due to the rinsate application collected from the first and second rinses.
Territorialization of the REDD + strategy in the Bribri indigenous people, Talamanca, Costa Rica
Authors: Marín-Herrera Maritza , Correa-Correa Heidy , Blanco-Wells Gustavo
Published: April 2021

Abstract This article explores how the attempt of implementing REDD+ affects the livelihoods and nature valuation of the Bribri indigenous people in Talamanca, Costa Rica. The analysis is done using a case study, discourse analysis and collective hermeneutics in documents and interviews produced by international, national, and local social actors. Controversies in the REDD+ strategy have been manifested in the initiative’s de/re/territorialization processes. These processes are legitimized by technocratic discursive strategies associated with climate change mitigation, produced in multilateral negotiations, and adapted by national institutions for purposes not aligned with the interests of the communities. It is concluded that the implementation of REDD + in indigenous territories in Costa Rica gives way to i) the commoditization of nature, participation and traditional forms of governance; ii) the consolidation of a climate eco-governmentality based on the fragmentation of nature; iii) building representations of vulnerable and impoverished indigenous people, and thus justifying intervention in their territories.
OUTCOME INDICATORS OF MULTI-PROFESSIONAL DIABETES CARE IN A REFERENCE SERVICE
Authors: Moreira Tatiana Rebouças , Silva Lucilane Maria Sales da , Torres Raimundo Augusto Martins , Silva Maria Rocineide Ferreira da , Oliveira Adriana Catarina de Souza
Published: April 2021

ABSTRACT Objective to identify outcome indicators of the multi-professional Diabetes Mellitus care of a reference outpatient service. Method a descriptive study of evaluative nature, according to the health evaluation framework, carried out by documentary analysis of 173 medical charts, from August to October 2018. The variables were analyzed in the Statistical Package for the Social Science (SPSS), version 22.0, by descriptive statistics, as well as the association of variables, with the Chi-square, Mann-Whitney, and Wilcoxon tests being used, considering p-values ≤ 0.05 as statistically significant. Results predominance of older adult women, with a mean diagnosis time of 11.9 years. The tracking of complications due to Diabetes Mellitus occurred in 90.2% of the users, with a prevalence of 68.2%, of which 34.7% were diagnosed in the service. Absenteeism was 21.4%. The systolic and diastolic arterial pressure and total cholesterol parameters were in line with the proposed goals, while glycated hemoglobin (A1c), fasting glycaemia, HDL-c, LDL-c, triglyceride fractions, and BMI did not reach the target range. There was a significant reduction in final A1c, comparing to initial A1c, as well as an increase in the proportions of users who reached the goals in glycemic control. Conclusion a significant improvement in glycemic control, despite the fact that the parameters did not fully meet the goals, ratifying the importance of an effective assistance model for successful care strategies of Diabetes Mellitus.
Speech-language-hearing instruments to assess peripheral facial palsy: an integrative literature review
Authors: Pereira Mariane Maião , Bianchini Esther Mandelbaum Gonçalves , Silva Mabile Francine Ferreira , Palladino Ruth Ramalho Ruivo
Published: April 2021

ABSTRACT Purpose: to describe and analyze the clinical instruments that assess peripheral facial palsy through an integrative literature review. Methods: the precepts for this type of review were followed: research question, identification, selection of studies, and critical analysis. The Virtual Health Library (VHL), Scientific Electronic Library Online (SciELO), Google Scholar, and PubMed databases were accessed to search for fully available articles published in national journals between January 2008 and July 2018. The terms used in the search were “Speech, Language and Hearing Sciences”, “Evaluation”, and “Facial Paralysis”, in both English and Portuguese. The data obtained were organized per author, title, objective, instruments used, description of the instruments, and application procedures used in the articles. Results: out of the total 992 articles found, only 18 met the inclusion criteria of the research. In most of them, there was only the citation of the assessment instruments or considerations about them, without fully describing the application procedures. Conclusion: the study identified publications that indicate the use of clinical and speech-language-hearing assessment instruments. However, further detailing is necessary regarding the assessment procedures to help develop and refine the speech-language-hearing methodologies and techniques.