bluuebunny/crossref_metadata_2025 huggingface dataset:
Modified Risk of Malignancy Index (RMI 5) in ovarian tumor
Authors: Joshi Rijuta , Baral Gehanath
Published: August 2021

Aims: To evaluate the role of modified RMI (RMI 5) in pre-operative evaluation of ovarian tumor.
Methods: It was a prospective cross sectional study done in Paropakar Maternity and Women’s Hospital from May to August 2018. During the study, 72 women with ovarian tumor were analyzed. RMI5 was calculated using the ultrasound score, Doppler score, menopausal status and CA125. Cut-off of 200 was used for malignancy discrimination. Chi square test was used to calculate the statistical significance which was set at 0.05. Receiver Operator Characteristics curves for RMI and its individual parameters were plotted using SPSS.
Results: There were 72 ovarian tumors operated in four months and mean age was36 years with 10 (14%) at post-menopause. The mean value of RMI 5 was 38 for benign tumors, 80 for borderline tumors and 899 for malignant tumors. The area under curve for RMI 5 was 0.993 for cut-off of 200. The diagnostic accuracy of RMI 5 was 94.4 which was similar to that of Doppler score 2 (94.7) while it was much higher than that of the rest of the parameters (CA-125: 72, ultrasound score: 87 and postmenopausal status: 88.9).
Conclusions: RMI 5 is better for malignancy prediction of ovarian masses instead of individual parameters like menopausal status, CA125 and ultrasound score.
“Sack of marble” appearance in mature cystic teratoma: an unusual finding
Authors: Shrestha Prajmi , Baral Gehanath , Bhansakarya Rakina , Chaudhary Amar Nath
Published: August 2021

Mature cystic teratoma (Dermoid) of ovary is a benign germ cell tumor consisting predominantly of ectodermal derivatives. In rare occasion sebaceous material may get aggregated to form marble like appearance because of continuous mobility of Dermoid and its content. Such a case in a menopausal woman has been presented in this report.
Report of a case with partial trisomy 9 mosaicism
Authors:   Hanoi Medical University, Hoang Thi Hai , Hoang Thi Ngoc Lan ,   Hanoi Medical University,   Hanoi Medical University Hospital, Vu Thi Ha ,   Hanoi Medical University,   Hanoi Medical University Hospital, Nguyen Thi Sim ,   Hanoi Obstetrics and Gynecology Hospital, Ho Khanh Dung ,   Hanoi Obstetrics and Gynecology Hospital, Doan Thi Kim Phuong ,   Hanoi Medical University,   Hanoi Medical University Hospital
Published: August 2021

Trisomy 9 syndrome and other related abnormalities such as full or mosaic trisomy 9 are very rare human chromosomal disorders. The disorders cause early pregnancy loss or death within 20 days after the birth which is accompanied by complex birth defects. The case reported here is a 26-year-old female, identified with partial trisomy of chromosome 9 by Array comparative genomic hybridization -aCGH, but has a longer life than reported in the medical literature and can give birth. The patient did not have abnormal mental or motor problems; no morphological ultrasound abnormalities; curved thumb and scattered warts on the left hand; gave birth to a healthy son after three consecutive stillbirths. The report has shown diverse clinical manifestations of trisomy 9 mosaic abnormalities in humans, contributing to a rare data source of trisomy 9 mosaic cases. Since then, improve knowledge of genetic counseling for rare cases of trisomy 9 mosaicism, especially in genetic counseling of prenatal diagnosis.
Evaluation of the chemical components and some bioactive compounds of the peppermint essential oil (Mentha arvensis L.) cultivated in Vietnam
Authors:   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology, Tran Bao Tram , Nguyen Thi Hien ,   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology, Truong Thi Chien ,   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology, Phan Xuan Binh Minh ,   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology, Nguyen Thi Thanh Mai ,   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology, Hoang Quoc Chinh ,   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology, Vu Xuan Tao ,   Center of Experimental Biology, National Center for Technological Progress, Ministry of Science and Technology
Published: August 2021

Vietnam has diverse plant resources and many species are considered to be valuable medicinal sources. Studying, seeking, and evaluating the bioactive compounds from plants is a valuable research endeavor for producing human healthcare products. Peppermint (Mentha arvensisL.) is widely cultivated in Vietnam as a raw material for the production of essential oils serving local needs and exports. This study compared the chemical components and some bioactive compounds in essential oil from Mentha arvensisL. cultivated in Thai Binh, Binh Thuan, and An Giang provinces. The essential oil yields in all samples ranged from 0.69 to 0.84%. Gas chromatography analyses identified 29 substances in total. Menthol and menthone were the two main ingredients in the oils, accounting for 53.62-62.61% and 18.81-21.06%, respectively. Furthermore, all essential oils exhibited free radical scavenging capacity in vitroand antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli. The plants collected in Thai Binh had the highest content of essential oil, menthol, and menthone, as well as the strongest bioactivities.
Compatibility of Orius insidiosus (Hemiptera: Anthocoridae) with Amblyseius swirskii (Acari: Phytoseiidae) for control of Flankliniella occidentalis (Thysanoptera: Thripidae) in pepper
Authors: Lorenzo Larregui Maria Eugenia , Bao Leticia , Grille Gabriela , Mendez Luciana , Bonato Oliver , Basso César
Published: August 2021

Biological control programs in greenhouses increasingly resort to the release of several natural enemies simultaneously. In Uruguay, pest management in peppers is based on the release of Orius insidiosus and Amblyseius swirskii, to control Frankliniella occidentalis and Bemisia tabaci. Amblyseius swirskii can feed on both preys. Zoophytophagous predators not only feed on pests or plant food, but also on natural enemies with which they share prey (intraguild predation). Hence, the combined release of generalist predators could have a negative result in the control of the target pest. Thus, it was important to evaluate the compatibility of O. insidiosus and A. swirskii as predators of F. occidentalis. Studies carried out at Petri dishes level assessed: (1) the effect of the density and the composition of the prey on their predation by O. insidiosus, (2) the change of prey by O. insidiosus and (3) the effect of the genus of O. insidiosus on prey preference. Results show that if the relative densities of F. occidentalis and A. swirskii varied, O. insidiosus always changed to the most abundant prey. Male and female O. insidiosus preferred nymphs of F. occidentalis over A. swirskii, and females killed more prey than males. Since O. insidiosus fed on A. swirskii, it is advisable to be cautious when combining anthocorids and phytoseid mites for the F. occidentalis control. Studies at greenhouse will be necessary to clarify the final effect of both predators.
Przyimki na, w oraz do przed nazwami państw, krajów i krain. Historia i współczesne wahania normatywne
Authors: Łaziński Marek
Published: August 2021

The article presents historical changes of prepositions preceding names of states, countries, and regions in Polish with the main focus on the contemporary discussion about the choice of the prepositions with names of eastern neighbours of Poland. According to dictionaries and grammars these names: Ukraina, Białoruś, and Litwa require the preposition na instead of the locative w and the adlative do, which are typical for the vast majority of land names, except for islands and peninsulas. Query in historical corpora since the 17th century showed that the preposition na had proliferated in reference to regions which belonged to the same country, importantly, not only with reference to Poland. It is also attested for pats of the Jagiellonian dynas-tic union or lands that had belonged to states that ruled parts of Poland under Partition. Despite this ten-dency, before the 19th Century, the preposition most frequently used with the names Litwa and Ukraina were the locative w and the adlative do. The traditional use of w and do in the past, typical colocations of na with regions rather than independent states, an animated discussion in the media, and the fluctuation of norm attested in the dictionaries of the last century – all these factors weigh in favour of admitting both preposi-tional patterns: na and w/do with the names of three states, eastern neighbours of Poland.
Accuracy of SARS-CoV-2 molecular laboratory testing: insight on recurrence infection and the new emergent strains
Authors: Hassan Al-Griw Huda
Published: August 2021

The rapid spread of the SARS-CoV-2 virus and increased number of deaths urged the world to provide accurate diagnostic procedures and apply the correct prevention measures to eradicate the disease. Molecular assays are designed to test the presence of virus RNA. The assays have wanting accuracy represented by false positive and false negative results, in particularly with continuous emerging of SARS-CoV-2 genetic variability. Miss interpretation of the test results can lead to bad outcomes for both individuals and the surrounding community when assuming the test is perfect. This review provides an update of the currently available molecular laboratory methods and address the effect of ongoing SARS-CoV-2 genetic variability on the performance of RT-PCR, the problem of re-positive test result in recovered patients and provides elements to be considered for performing SARS-CoV-2 test and interpreting the test results.
Efektivitas Pembelajaran Remedial Secara Daring pada Masa Belajar dari Rumah di SMA Negeri 1 Majene
Authors: Firman Firman
Published: August 2021

Proses pembelajaran dari rumah membawa berbagai dampak pada hasil belajar peserta didik, salah satunya yaitu tidak tercapainya nilai ketuntasan minimum sehingga diperlukan pembelajaran remedial. Penelitian ini adalah penelitian deskriptif kuantitatif yang bertujuan untuk mengetahui efektivitas pembelajaran remedial yang dilaksanakan secara daring selama periode belajar dari rumah di SMA Negeri 1 Majene. Efektifitas pembelajaran ditinjau dari dua aspek yakni hasil belajar dan proses pembelajaran. Analisis data hasil belajar menunjukkan nilai Normalized Gain (N Gain) sebesar 0.55 yang berarti pembelajaran remedial efektif dalam meningkatkan hasil belajar. Hasil analisis angket respon guru  dan peserta didik  secara berturut-turut adalah 71, 67% dan 76,55%  yang berarti bahwa baik guru dan peserta didik menilai bahwa pembelajaran remedial secara daring efektif untuk dilaksanakan. Hal ini menunjukkan bahwa pembelajaran remedial secara daring di SMA Negeri 1 Majene efektif dari sudut pandang proses dan hasil pembelajaran.
Biodiversitas Mangrove di Desa Terapung dan Totobo Sulawesi Tenggara
Authors: Erfina Erfina
Published: August 2021

Mangrove adalah ekosistem lahan basah pasang surut yang sangat produktif dan ditemukan di sepanjang pantai tropis maupun subtropic, mempunyai peranan sangat penting di daerah estuaria, merupakan ekosistem yang sangat unik dan rapuh serta sebagai daerah pertemuan antara lingkungan darat dan laut. Indonesia sebagai negara maritim dan kepulauan terbesar di dunia dengan jumlah pulau mencapai 17.504 pulau dan panjang garis pantai sekitar 95.181 km dengan kondisi biofisik lingkungan dan iklim beragam. Hal ini, didukung dengan ekosistem mangrove terluas di dunia (3.49 juta ha), dimana terdapat sekitar 202 jenis mangrove dengan 166 jenis di Pulau Jawa, 157 jenis di Pulau Sumatera, 150 jenis di Pulau Kalimantan, 142 jenis di Pulau Irian Jaya, 133 jenis di Pulau Maluku, 120 jenis di Kepulauan Sunda Kecil dan 135 jenis di Pulau Sulawesi, sehingga Indonesia dikenal sebagai negara mega biodiversitas. Penelitian ini bertujuan melihat biodiversitas mangrove dan sebagai acuan dalam menambah informasi (database) mengenai kelimpahan mangrove yang ada di Sulawesi Tenggara. Penelitian dilaksanakan di pesisir pantai Desa Terapung dan Desa Totobo Sulawesi Tenggara. Pengambilan data vegetasi mangrove di lokasi penelitian menggunakan metode tanpa plot Point Centered Quarter Method (PCQM) yang masing-masing lokasi diletakan dibuat baseline 100 m, jarak antara sub transek 25 m dan pengukuran parameter lingkungan. Hasil penelitian di dua lokasi ditemukan 7 spesies yaitu: Bruguiera gymnorrhiza (L.) Lamk., Bruguiera sexangula (Lour). Poir. Rhizophora mucronata Lamk. Xylocarpus granatum Keon. Sonneratia Alba J.E Smith dan Avesinnia marina (Forsk) Vierh.  Namun, jenis yang banyak ditemukan pada stasiun 1 (desa Marobo), karena didukung oleh subtract dan parameter lingkungan (pH tanah: 5 – 7,8), (Kelembaban udara: 72,1—81,55%), (Temperatur udara: 30,45—34,4 0C), (intensitas cahaya 27.5--541.5cd) dan salinitas berkisar (20 -- 30‰).
Response in Cadmium Tolerance of Penicillium cyclopium Westling Subsequent to Exposure to Gamma Irradiation
Authors: Das Dipanwita , Chakraborty Debargha , Chakraborty Anindita , Santra Subhas Chandra
Published: August 2021

Role of gamma irradiation in modulating 1.1 times more cadmium (Cd) tolerance in Penicillium cyclopium Westling has been detailed in this paper. Augmentation in metal tolerance was recognized by escalation in response to Cadmium and Cd removal efficacies than that of their un-irradiated group. FTIR spectra and electron microscopic photographs further strengthen the role of low absorbed dose of gamma in modulating Cd tolerance in P.cyclopium. Up regulated activities of anti-oxidatives in gamma exposed fungal groups might be the reason for enhanced Cd tolerance than that of their un-irradiated counter parts. This findings reveal a positive and eco-friendly step for heavy metal bioremediation and metal stressed lignocellulosic waste degradation.
Visual Clustering Analysis of some traditional Mango (Mangifera indica L.) varieties of Murshidabad District, West Bengal using Clust Vis web tool
Authors: De Mitu , Dutta Subhasree , Ray Susanta , Dey Santi Ranjan
Published: August 2021

A clustergram or a heatmap is one of several techniques that directly visualize data without the need for dimensionality reduction. Heatmap is a representation of data in the form of a map or diagram in which data values are represented as colours. Cluster heatmaps have high data density, allowing them to compact large amounts of information into a small space. “ClustVis”, is a web tool for visualizing clustering of multivariate data using Principal Component Analysis and Heatmap. Using this web tool, genetic relationships among the traditional mango (Mangifera indica L.) varieties can be visualized. In this investigation ten (10) indigenous mango varieties were selected. These were elite varieties of Murshidabad viz. Anaras, Bhabani, Champa, Dilpasand, Kalabati, Kohinoor, Kohitoor, Molamjam. The morphological and biological characters were analyzed using this tool. Analysis and assessment of the current status of mango genetic resources will be important for ascertaining the relationship among traditional varieties. This data may be used for appropriate conservation and sustainable utilization measures. This information may also be needed to carry out breeding programs to develop improved cultivars for sustainable livelihoods of local communities.
“Many and Dreadful Disasters”
Authors: Walchester Kathryn
Published: August 2021

Our recent experiences of quarantine during the COVID-19 outbreak have exposed the vulnerability of poorer members of society and has highlighted their increased suffering during the period of restricted mobility. This article considers the way in which quarantine exacerbates inequalities from a historical perspective, looking at enforced periods of restricted travel and its impact on servants and lower-class British travelers of the eighteenth century in Europe. It examines both the history of representations of plague and contagion, and some of the human reactions to fears of disease, one of which was the imposition of quarantine measures. Three main sources are referred to: Patrick Brydone’sA Tour through Sicily and Malta in a Series of Letters to William Beckford, published in 1790; Elizabeth, Lady Craven’s “A Journey through the Crimea to Constantinople in a series of Letters,” published in 1789; and the unpublished letters of William Fletcher, manservant to Lord Byron, from his journeys in 1811. The texts produced by these travelers from the eighteenth century offer rich material for the consideration of the impact of mobility and immobility both of and on the body and how these experiences were strikingly different depending on the social class of the traveler.
Editorial
Authors: Welch Penny , Wright Susan
Published: August 2021

The focus of this issue of Learning and Teaching: The International Journal of Higher Education in the Social Sciences is on institutional practices that shape and limit students’ and academics’ identities and how these restrictions can be overcome.
The irony of an ‘international faculty’
Authors: Wang Chenyu
Published: August 2021

Using the autoethnographic case study method, this article examines how my positionality as a foreign-born faculty member intersects with the institutional rhetoric of diversity and inclusion present in many predominantly White institutions. My vignettes show that foreign-born faculty, although contributing to the representation of diversity numbers, are positioned as knowledge providers in the discussions about the ‘global’, the ‘cultural’ and sometimes the ‘racial’, thus, ironically reinforce the embedded White institutional culture. This article argues that foreign-born faculty members could make use of their cultural positions to unpack the classed and racial culture on campus and to cultivate students’ anthropological sensibility. In other words, foreign-born faculty are in a unique position of recognising the limitations of the current diversity and inclusion rhetoric in predominantly White institutions (PWI), but also, they have the potential of decentring the White, middle-class cultural norms. This article concludes with some pedagogical implications.
Encounters with borders
Authors: Dixit Priya
Published: August 2021

This article examines (im)obility in the global visa regime through the experiences of a Global South academic working in the Global North. Drawing on an autoethnographic account of a visa application, this article outlines the ways in which the global visa regime negatively affects a Global South academic’s life. Visa regulations constitute a particular Global South academic subject in the Global North, one whose academic career is characterised by uncertainty and anxiety, as visas can limit access to promotions and to fieldwork and research opportunities. Visa experiences can thus contribute to alienation and non-belonging of Global South scholars in academia, while impacting knowledge production and teaching.
Using differentiated teaching to address academic diversity in higher education
Authors: Thuen Jørgensen Matias , Brogaard Lena
Published: August 2021

University educators increasingly face groups or classes of students with diverse academic levels, challenging a ‘one size fits all’ approach to teaching. In this article, we examine whether and how differentiated teaching, especially the concept of student readiness, can be applied to assess and respond to academic diversity, exemplified by two different cases; a methods lecture series and a peer-evaluation seminar. Each case presents specific tools, activities and techniques inspired by differentiated teaching that may be replicated or used for inspiration in similar contexts. The results include better fulfilment of intended learning outcomes, teaching that is perceived to be meaningful by students and educators, and a more inclusive learning environment. The two cases demonstrate the utility of differentiated teaching in higher education, challenging the prevalent assumption that differentiated teaching does not apply well to a university setting.
Covid-19 and Media Representation: A Multimodal Study of Positive Discourse in Pakistani Television Commercials
Authors: Nasir Muhammad Haseeb , Mirza Ejaz
Published: August 2021

The present study seeks to highlight the role of mainstream media in the dissemination of positive discourse, creating awareness among the masses with regard to the outbreak of COVID-19 in Pakistan. Media discourse plays a significant role in promoting ideology at a larger scale due to its vast viewership across the country. These ideological narratives are implicitly employed by the advertisers through several multiple resource systems. Electronic media has the power to (re)frame the ideology of a larger audience via significant visual/linguistic content and paves the way for social change through viable social institutions. The study follows the theoretical stance of Multimodal Text Analysis propounded by Kress and Leeuwan (2006). The data is comprised of some popular television commercials which are broadcast on the most viewed channels during the peak time viewership in the Pakistani context. The purposive sampling technique has been employed for the data collection process, including only those commercials that largely reflect COVID-19 patterns. The study finds that the commercials present layers of meanings via several orders of signification where the representation has been aimed at creating awareness to a greater extent among the general public so that they can take essential precautions and help to fight against the pandemic.
The surgical management of pituitary apoplexy with occluded internal carotid artery and hidden intracranial aneurysm: illustrative case
Authors: Zhu Jian-Dong , Xie Sungel , Xu Ling , Xie Ming-Xiang , Xiao Shun-Wu
Published: August 2021

BACKGROUND

Approximately 0.6% to 12% of cases of pituitary adenoma are complicated by apoplexy, and nearly 6% of pituitary adenomas are comorbid aneurysms. Occlusion of the internal carotid artery (ICA) with hidden intracranial aneurysm due to compression by an apoplectic pituitary adenoma is extremely rare; thus, the surgical strategy is also unknown.

OBSERVATIONS

The authors reported the case of a 48-year-old man with a large pituitary adenoma with coexisting ICA occlusion. After endoscopic transnasal surgery, repeated computed tomography angiography (CTA) demonstrated reperfusion of the left ICA but with a new-found aneurysm in the left posterior communicating artery; thus, interventional aneurysm embolization was performed. With stable recovery and improved neurological condition, the patient was discharged for rehabilitation training.

LESSONS

For patients with pituitary apoplexy accompanied by a rapid decrease of neurological conditions, emergency decompression through endoscopic endonasal transsphenoidal resection can achieve satisfactory results. However, with occlusion of the ICA by enlarged pituitary adenoma or pituitary apoplexy, a hidden but rare intracranial aneurysm may be considered when patients are at high risk of such vascular disease as aneurysm, and gentle intraoperative manipulations are required. Performing CTA or digital subtraction angiography before and after surgery can effectively reduce the missed diagnosis of comorbidity and thus avoid life-threatening bleeding events from the accidental rupture of an aneurysm.
Contralateral insular epileptogenic hub causing seizure relapse after opercular focal cortical dysplasia surgery and response to radiofrequency thermocoagulation: illustrative case
Authors: Jayapaul Pushkaran , Aslam Shameer , Rajamma Bindhu Mangalath , Gopinath Siby , Pillai Ashok
Published: August 2021

BACKGROUND

The reevaluation and management of seizure relapse following resective surgery in magnetic resonance imaging (MRI)-negative pharmacoresistant epilepsy remains a significant challenge.

OBSERVATIONS

A 25-year-old right-handed male with medically refractory epilepsy presented with nonlocalizing electroencephalography (EEG) and MRI. Stereo-EEG (SEEG) implantation based on semiology and positron emission tomography imaging revealed a left frontal opercular focus with rapid bilateral insular ictal synchrony. The initial epileptogenic zone was resected and pathologically proven to be type 2A focal cortical dysplasia (FCD). Seizure relapse after 9 months was eventually reinvestigated, and repeat SEEG revealed a secondary epileptogenic focus in the contralateral insula. A novel technique of volumetric stereotactic radiofrequency ablation (vRFA) was utilized for the right insular focus, following which, the patient remains seizure-free for 20 months. He suffered a transient bilateral opercular syndrome following the second intervention that eventually resolved.

LESSONS

The authors present clinical evidence to suggest epileptogenic nodes distant from the primary focus as a mechanism for seizure relapse following FCD surgery and the importance of bilateral insular SEEG coverage. The authors also describe a novel technique of minimally invasive vRFA that allows ablation of a larger volume of cerebral cortex when compared to conventional bedside SEEG electrode thermocoagulation.
A pure extradural hemangioblastoma mimicking a dumbbell nerve sheath tumor in cervical spine: illustrative case
Authors: Piquer-Belloch José , Rodríguez-Mena Ruben , Llácer-Ortega José Luis , Riesgo-Suárez Pedro , Rovira-Lillo Vicente , Flor-Goikoetxea Gamo Alain , Cremades-Mira Antonio , Llopis-San Juan Eva
Published: August 2021

BACKGROUND

Spinal extradural hemangioblastomas (HBs) are quite uncommon, with most reported cases involving the thoracic and lumbar areas. Therefore, the presence of a dumbbell-shaped pure extradural cervical HB is exceptional, making preoperative diagnosis particularly challenging.

OBSERVATIONS

The authors report a case of a 27-year-old woman who presented to their outpatient clinic with progressive cervicobrachialgia and numbness in the left arm. Magnetic resonance imaging showed a C5–6 intradural extramedullary lesion, and, despite some atypical features, the diagnosis of a possible neurogenic tumor was made. A multidetector computed tomography scan and angiography confirmed the expansion and remodeling of the left neural foramen as well as the highly vascularized nature of the mass. Preoperative embolization of the lesion was performed. Complete tumor resection was accomplished, followed by a C5–6 posterior fusion. Histopathology and immunohistochemistry revealed an HB.

LESSONS

HBs should be considered among the differential diagnosis of cervical extradural tumors. Exhaustive preoperative workup and surgical planning are decisive in order to attain gross-total resection with favorable outcomes.
Функціональний стан печінки у хворих із хронічною серцевою недостатністю залежно від наявності неалкогольного стеатогепатиту
Authors: Virstyuk N.G. , Vakalyuk I.I. , Cherkashyna O.J. , Kazmiryk V.M.
Published: August 2021

Результати досліджень довели вплив неалкогольної жирової хвороби печінки на перебіг серцево-судинних захворювань. Недостатньо вивченим залишається функціональний стан застійної печінки при хронічній серцевій недостатності (ХСН) у поєднанні з неалкогольним стеатогепатитом (НАСГ). Мета роботи — вивчення показників функціонального стану печінки у хворих на ХСН ІІА стадії ІІІ ФК за класифікацією NYHA (New York Heart Association) залежно від наявності НАСГ. Матеріали та методи. Обстежено 72 хворих на артеріальну гіпертензію (АГ), ускладнену ХСН ІІА стадії ФК ІІІ за NYHA: 36 хворих без НАСГ (І група), 36 хворих із НАСГ на стадії фіброзу F1-F2 (ІІ група). Групу обстежених становили 31 (43,0%) чоловік і 41 (57,0%) жінкавіком (66,9±5,4) року. Контрольну групу становили 20 практично здорових осіб. Вивчали показники функціонального стану печінки, ліпідограми, а також вміст С-реактивного протеїну (СРП), фактора некрозу пухлин альфа (ФНПα) і NT-pro BNP у крові імуноферментним методом зі статистичним опрацюванням. Результати. Зміни функціонального стану печінки були більшими за поєднання ХСН і НАСГ: у пацієнтів ІІ групи вміст білірубіну, активність АсАТ, АлАТ, ЛДГ, ГГТП і ЛФ були вищими, показники дисліпідемії вираженішими порівняно з пацієнтами І групи (p<0,05). Вміст СРП у крові пацієнтів ІІ групи перевищував такий у здорових у 7,88 раза, у пацієнтів І групи — у 2,26 раза (p<0,05); вміст ФНПα — у 3,86 і 1,24 рази (p<0,05); NT-proBNP — у 4,79 і 1,49 рази відповідно (p<0,05). Виявлено кореляції між показниками ФНПα й активністю АлАТ, ГГТП, холінестерази (r=+0,61; r=+0,42; r= –0,42 відповідно; p<0,05); між ФНПα і NT-pro BNP (r=+0,73; p<0,05); між АлАТ, ГГТП і NT-pro BNP (r=+0,55; r=+0,49 відповідно; p<0,05).Висновки. Поєднання ХСН ФК ІІІ за NYHA з НАСГ характеризується помірною гепатомегалією, порушенням функціонального стану печінки із цитолітичним, холестатичним синдромами, порушенням синтезуючої функції печінки та наростанням дисліпідемії; посиленням субклінічного системного запалення і ХСН за збільшенням у крові вмісту СРП, ТНФα і NT-pro BNP.
Алкогольна хвороба печінки: фокус на L-орнітин-L-аспартат
Authors: Sova V.A.
Published: August 2021

У статті наведено результати дослідження ефективності L-орнітину-L-аспартату (Гепатокс) при алкогольній хворобі печінки. У дослідженні на базі клініки «Надія» (м. Київ) і КМП «Клінічна лікарня «Психіатрія» у м. Києві взяли участь 32 пацієнти, що були розподілені на дві групи: основну, яка отримувала базову терапію й Гепатокс 10 г в/в, і контрольну, де хворі отримували тільки базову терапію. Через п'ять днів у контрольній групі на тлі лікування Гепатоксом у хворих значно зменшилися біохімічні показники АЛТ, АСТ, білірубіну. Застосування Гепатоксу в комплексному лікуванні алкогольної хвороби печінки допомагає не тільки значно відновити функції печінки, а й поліпшити когнітивні функції пацієнта, що проявляється поліпшенням якості життя.
Festive Epistles of St. Ambrose of Optina: the Linguo-stylistic Aspect
Authors: Артюхин Мелхиседек , Ишков Алексей , Егорова Наталия Андреевна , Цветкова Анна Анатольевна
Published: August 2021

В статье рассмотрены праздничные письма-поздравления прп. Амвросия Оптинского (1812-1894), составляющие часть его эпистолярного наследия. Описаны основные отличия данного вида писем от индивидуальных писем старца к частным лицам, описана история создания, проанализированы основные композиционные и стилистические особенности посланий, а также прослежена их связь с жанром церковной проповеди. Статья раскрывает значение праздничных посланий прп. Амвросия в эпистолярном наследии Русской Православной Церкви.

The article «Festive Epistles of St. Ambrose of Optina: linguistic and stylistic aspect» describes the structure of festive epistles by reverend Amvrosy Optinskiy (1812-1894). It denotes the main differs of this epistolary type and private letters, tells about the purpose and history of creation, and also describes it’s stylistic features. The article traces the relationship between festive epistles and the genre of sermon in XIX century. The material of the article allows to get a detailed idea of this epistolary type and it’s meaning in the spiritual heritage of the Russian Orthodox Church.
Vocative Wording in Oratorical Speeches in Modern Secular and Spiritual Discourse (as Exemplified in Written and Oral Texts of the President of the Russian Federation V. V. Putin and the Patriarch of Moscow and all Russia Kirill)
Authors: Смолененкова Валерия Владимировна
Published: August 2021

Статья посвящена тенденциям в оформлении обращений в публичных текстах двух влиятельных публичных деятелей современной России. Рассматриваются корреляции между формулировками обращения и коммуникативными ситуациями. Делается попытка увидеть тенденции в формировании нормы обращений к коллективному и индивидуальному адресату.

The article is devoted to the trends in vocative wording in public texts of two influential public figures in modern Russia. The author considers correlations between the particular wording of the address and communicative situations. She tries to find tendencies in vocative standardization both for the texts addressed to the collective or individual addressee.
KONSEP BIOPHILIC DALAM PERANCANGAN ARSITEKTUR
Authors: Justice Ronald
Published: August 2021

Abstract: Various attempts were made to reconnect humans with the buildings and places they inhabit. Biophilic design, as the newest theory of reconnection, essentially incorporates organic life into the built environment. This study aims to explore the biophilic concept in architectural design as a literacy reference in the field of architecture. The research method is through literature review and interviews with the primary data source of an architect and one other architect as a secondary data source. The collected data were analyzed using the Biophilia Architecture theory by Prof. Samalavicius (2020). The analysis showed that the primary source was not included in the Biophilia category, while the secondary data sources had applied the Biophilia concept. The study based on the Biophilic Architecture theory concludes that the concept of biophilic design is an architectural approach to solving residential needs problems by bringing the natural atmosphere into space as a therapy for its occupants both psychologically and physiologically. Meanwhile, understanding the creativity of an architect's work can be done through Intangible (intangible) and Tangible (real). The architectural design process consists of the analysis stage, the synthesis stage, and the evaluation stage, which are known as the divergent, transformation, and convergent stages.Abstrak: Berbagai upaya dilakukan untuk menghubungkan kembali manusia dengan bangunan dan tempat yang mereka huni. Desain biofilik sebagai teori rekoneksi terbaru, menggabungkan kehidupan organik ke dalam lingkungan binaan secara esensial. Penelitian ini bertujuan menggali konsep biophilic dalam perancangan arsitektur sebagai referensi literasi dalam bidang arsitektur. Metode penelitian melalui kajian literatur dan interview sumber data primer seorang arsitek dan satu orang arsitek lainnya sebagai sumber data sekunder. Data yang terkumpul dianalisis menggunakan teori Biophilia Architecture oleh Prof. Samalavicius (2020). Hasil analisa menunjukkan sumber primer belum termasuk kategori Biophilia, sedangkan sumber data sekunder telah menerapkan konsep Biophilia. Pengkajian berdasarkan teori Biophilic Architecture disimpulkan bahwa konsep parancangan biophilic merupakan pendekatan arsitek untuk memecahkan permasalahan kebutuhan hunian dengan membawa suasana alam kedalam ruang sebagai terapi bagi penghuninya baik psikologis maupun fisiologis. Sedangkan memahami kreativitas karya arsitek dapat dilakukan melalui Intangible (tak berwujud) dan Tangible(nyata). Proses perancangan arsitektur terdiri dari tahapan analisis, tahap sintesis, dan tahap evaluasi yang dikenal dengan tahap divergen, transformasi, dan konvergen.
ANALISIS TIPOLOGI ARSITEKTUR RUMAH MASYARAKAT TANI DI BANARAN KABUPATEN TUBAN
Authors: Santri Tyas
Published: August 2021

Abstract:. Archipelago architecture is one of the identities of the Indonesian state. Archipelago architecture in Indonesia can be found in rural areas, hamlets, villages, and coastal areas. The architecture that develops in the hamlets in Indonesia can be a potential for regional tourism development. The settlement of the peasants in Banaran Hamlet is a settlement that is not too dense and the community houses have a distinctive architectural typology. This study aims to analyze the typology of the Banaran farming community houses. This study uses a typological approach with tracing methods in the literature and field studies which are then described qualitatively. This study presents the results of the analysis of typology of farm community houses in Dusun Banaran, Sidotentrem Village, Bangilan District, Tuban Regency, East Java.Abstrak: Arsitektur nusantara merupakan salah satu identitas negara Indonesia. Arsitektur nusantara di Indonesia dapat di jumpai di wilayah pedesaan, dusun, kampung, pesisir. Arsitektur yang berkembang di wilayah dusun-dusun di Indonesia dapat menjadi potensi untuk pengembangan wisata daerah. Permukiman masyrakat tani di Dusun Banaran, merupakan permukiman yang tidak terlalu padat dan rumah msyarakat memiliki tipologi arsitektur yang khas. Kajian ini bertujuan untuk menganalisis tipologi rumah masyarakat tani Banaran. Kajian ini menggunakan pendekatan tipologi dengan metode penuelusuran secatra kajian literatur pustaka maupun lapangan yang kemudian dideskriptif secara kualitatif. Penelitian ini menyajikan hasil analisis tipologi arsitektur rumah masyarakat tani di Dusun Banaran, Desa sidotentrem, Kecamatan bangilan, Kabupaten Tuban, Jawa Timur.
The economic policy of the self-proclaimed 4th transformation in Mexico
Authors: López Arévalo Jorge Alberto
Published: August 2021

The government of Andrés Manuel López Obrador set off many expectations in Mexico and in Latin America about a change of course for Mexico, it was thought that the ne-oliberal economic policy that had characterized Mexico since 1983 would be left be-hind. In 1983 Mexico undertook a structural change in its economy, characterized by three basic aspects: the consolidation of public finances; privatization of public compa-nies; trade liberalization. This economic policy remains on its basic foundations and the results are being aggravated by the Covid-19 pandemic. Currently a roadmap that leads to dismantling the neoliberal model in Mexico is nowhere to be seen, even though it is lashed out and held responsible for the country's economic, political and social problems almost every day.
Внешняя политика президента Мексики Андреса Мануэля Лопеса Обрадора. Растущая значимость vs строгий отбор в период 4-ой трансформации
Authors: Prado Lallande Juan Pablo
Published: August 2021

Based on the axiom that "the best foreign policy is the domestic one”, Mexican president, Andrés Manuel López Obrador stated that the international relations of the Mexican government would occupy a discrete place in his administration. However, due to external factors, foreign policy occupies increasingly relevant spaces on the presidential agenda. The purpose of the article is to review the most significant background, purposes, challenges, actions and results of the Mexican foreign policy implemented by López Obrador from 2019 to April, 2021. It is argued that, the relevance of foreign policy in this government is ascending, although it addresses issues selectively, which generates both achievements and challenges for this Latin American country.
Experimental Investigation on the Effect of Angles of Attack to the Flutter Speed of a Flat Plate in Axial Flow
Authors:   Politeknik Negeri Bali, Rahtika I Putu Gede Sopan , Suarta I Made ,   Politeknik Negeri Bali, Rusmariadi I Komang ,   Politeknik Negeri Bali, Sunu Putu Wijaya ,   Politeknik Negeri Bali
Published: August 2021

The application of flat plates to the field of wind harvesting requires a lot of research toward the understanding of the flutter behavior of the plates. There are shortages of articles that discuss the effect of varying the angles of attack to the flutter speed of a flat plate. This research aims to conduct a basic experimental research on the effect of relative position of a thin-flat plates to the direction of the air flow to its flutter speed. In this study, a thin-flat plate was placed in a subsonic wind tunnel to test its flutter speed. The position of the plate was varied in various angles of attack. The effect of the angles of attack to the flutter speed was observed.
Analysis of initiation of instability zones of drilling string and intensification of drilling process at well boring by rotating an d rotating-bit methods
Authors: Malinovskii Yu. A. , Uchitel А. D. , Lyalyuk V. P. , Tsvirkun S. L. , Vlasenkov D. P. , Datsenko S. Yu.
Published: August 2021

Instable operation of a drilling string can be caused by design flaws, unreasonably selected drilling modes, as well as specific features of the drilling by bit, fixed on a long flexible rod with initial irregularities. It was established that a drilling string under the influence of constant torque and longitudinal feed load is deformed along a screw line. It was shown that the source of the dynamic state initiation of a rotating drilling string is an alternative friction between rock and the instrument, as well as variation of potential energy of the drilling string at its twisting and untwisting. At the string twisting the potential anergy is accumulating, at the untwisting it is released. In this case the drilling sting length begins to increase and the work of feed force is imposed to this shifting resulting in the instrument beat over the rock. The torsion oscillating process causes longitudinal periodic shifting of the string end, which lead to joint longitudinal and bending oscillations of the whole drilling column. Systems of differential equations obtained describing the joint bending-longitudinal oscillations of a drilling string, caused by torsion vibrations, initiating at the contact of a drilling instrument with rock. Approximate solutions of the systems presented, which take place with the basic natural frequency of the torsion oscillations of a two-mass system instrument - string - rotator drive. In this case the amplitudes of the drilling string bending oscillations are associated with characteristics variation of the friction between the instrument and the rock as well as with the angular frequency of the drilling string rotation. Zones of dynamic instability at rotation of the deformed drilling string due to acting force factors, as well as initial irregularities and centrifugal forces revealed. It was shown that they are initiated at critical speeds of the drilling string rotation, which coincides with any natural frequency of the bending oscillations of the stave. To intensify the drilling process, recommendation elaborated for equipping the rotary drilling rig with an additional pneumatic hammer. A calculated diagram of a drilling string, equipped by an additional pneumatic hammer considered. Parameters of the hammer in terms of frequency and amplitude are matched with the translational speed of well drilling. The total longitudinal and transverse shifts can be obtained by superposition of self-exciting and induces shifts.
Modern concepts of refractory materials application in production of steel and cast iron
Authors: Aksel’rod L. M. , Garten V.
Published: August 2021

Refractory lining is an integral part of metallurgical facilities and requires constant perfection. Examples of successful interaction of specialists-steelmakers, companies-manufacturers of refractories and engineering companies on increasing efficiency of refractories application in steel industry presented. The wide application of drying and heating stations of steel ladles, EAFs, BOFs was noted because of using refractory gunned castable at their current repairs. The growth of unmolded refractory share in the BF production was shown. At the stoves repair technology of guniting and shotcreting is widely used. Transfer to application of modern concrete at lining of shoots, ramming mixtures and repairs with application of liquid concrete addition resulted in a decrease of labor­ intensiveness of repair work, accelerated the process of repair and considerably decreased specific consumption of refractory materi­als. Nevertheless, within a predictable period, despite of increase of unmolded refractories application, it is expected that the molded refractories would take the main share of the refractory market in the steelmaking. Creation of partial load conditions in a metallurgical facility is an important factor for increasing lining resistivity. Slag foaming in EAF screens radiation from electrodes in the process of the furnace running. Blowing of the final slag (preliminary enriched by magnesium oxide in case of necessity) forms a scull on the working surface of the BOF lining, thus preventing intensive contact of the refractory lining with steel melt and slag. Modem technologies of instrumental control the lining state of metallurgical facility within the period of its running considered, which allowto accomplish operation of hot repair at particular arears of the lining, avoiding overconsumption of the repair material. It was noted that apart from the task of decreasing specific expenses for refractory materials, the customers most often estimate the indirect costs, cover of loss and obtaining additional profit due to increase of metal production because of increase of overhaul period and decrease of time of lining repair. This is the purpose of cooperation of specialists of refractories manufacturers and metallurgical plants.
Development and research of new technologies for precision plasma cutting of metals
Authors: Anakhov S. V. , Pykin Yu. A. , Matushkin A. V. , Guzanov B. N.
Published: August 2021

Plasma torches of Russian origin concede to import metal-cutting plasma facilities by several parameters, in particular energy efficiency, quality of cut, degree of automation. To increase efficiency and safety of domestic electro-plasma technologies itь is necessary to perfect methods of analysis of known design solutions to provide new developments. The results of the plasma torch­es design widely used in metallurgical and machine-building technologies for air-plasma cutting of metals presented. It was noted that productivity, cutting quality and reliability of plasma equipment should be chosen as the main criteria of efficiency for plasma cutting technology. It was shown that special attention should be paid to improving the gas-vortex stabilizing method for the plasma forming gas, which ensures the efficiency of both the plasma torch and the plasma cutting process as a whole. Results of studies of a complex system for arranging the flow of plasma-forming gas through the channels of the gas-air path in the plasma torch and the subsequent creation of new systems for stabilizing the arc discharge of metal cutting DC plasma torches with high technological capabilities presented. The study was carried out by the methods of numerical simulation of gas-dynamic and thermo-physical pro­cesses for various designs of plasma torches. Optimized designs of plasma torches with various variants of gas-vortex stabilization systems were elaborated. A series of elaborated torches, which includes a single-stream plasma torches ПМВР-5 for precision cutting of medium thickness metals, as well as two-stream plasma torches ПМВР-9 for cutting metals of small and medium thicknesses presented. The last plasma torches use the technology of narrow-jet or compressed plasma and have no domestic analogues. A meth­odology of metal-cutting plasma torches designing by gas-dynamic, thermo-physical and acoustic criteria was elaborated. The results of experimental studies  showed that the use of new ПМВР-5 plasma torches allows to obtain precision cuts corresponding to the 1st and 2nd quality classes according to GOST 14792-80 on steels of the 09Г2С type of medium thickness. It was also shown that the use of new plasma torches makes it possible to perform precision finishing plasma cutting on low-carbon steels of medium thickness (without additional mechanical processing of the cutting edge) in the production technologies of welded joints.
Encuesta de percepción sobre riesgos del sistema Financiero - Julio de 2021
Authors:   Departamento de Estabilidad Financiera
Published: August 2021

En este informe se presentan los resultados de la Encuesta de Percepción Sobre Riesgos del Sistema Financiero, la cual busca identificar la perspectiva de diferentes agentes de la economía frente a los riesgos y vulnerabilidades más importantes que enfrenta el sector financiero, y evaluar cuál es el nivel de confianza que tienen en su estabilidad.