bluuebunny/crossref_metadata_2025 huggingface dataset:
Accuracy of C-Reactive Protein Level in the Diagnosis of Acute Appendicitis on Histopathology
Authors: Khan Asad Ullah , Rehman Maaz , Ishfaq Muhammad , Yousafzai Habibullah , Wajahat Kunwar , Tahir Ahmad Arsalan
Published: February 2023

Background: Acute appendicitis (AA) is one among most common condition requiring emergency surgery throughout the world. Acute appendicitis most common diagnosis in patients seeking medical help in emergency room due to acute abdomen causing 72,000 deaths among 16 million cases reported globally. This study will help the surgeons in making timely decisions, thus reducing the morbidity and mortality associated with complicated appendicitis. The aim of this study was to accuracy of C - reactive protein (CRP) levels in acute appendicitis. Material and Methods: Six-month descriptive cross-sectional research from 16 February to 16 August 2019 was completed. The Khyber Teaching Hospital in Peshawar served as the study's location. A total of 216 patients were monitored throughout this investigation. The history, clinical examination, and regular laboratory tests, such as the total leucocyte count (TLC) and differential leucocyte count (DLC) on admission, were used to make the diagnosis of acute appendicitis. All of these patients were given Nil by Mouth to prepare them for emergency surgery, and baseline testing included HBs Ag and Anti-HCV serology as well as pre-operative serum CRP levels (Liver function tests, renal function tests and serum electrolytes). Following preparation, every patient on the emergency list had surgery. Intra-operative results were recorded, and a biopsy was collected from the excised appendices and forward to histopathology for further processing. Results: The mean age in this research was 48 years, with an SD of 12.311. Male patients made up 55% of the total population, while female patients made up 45%. The diagnostic accuracy of C-reactive protein levels was determined to be 84.2% in this study. The specificity was found to be 33.3%, while the sensitivity was observed to be 85.7%. By using histopathology, it was discovered that the positive predictive value was 97.2% and the negative predictive value was 84.2%. Conclusion: According to our study, using histopathology, the diagnostic accuracy of C-reactive protein levels was 84.25% with sensitivity of 85.71%, specificity of 33.33%, and positive predictive values of 97.25% and 184.25%. The findings will also open the door for any further research in this area. . The higher CRP levels will therefore predict the complexity of acute appendicitis and help the general practitioners to do early referrals therefore avoiding life threatening complications Keywords: Acute Appendicitis, C-Reactive Protein, Histopathology, CRP, Gold Standard
Analyzing the Health Status of Slum Dwellers: An Evidence of Lahore, Pakistan
Authors: Safdar Muhammad Hassan , Ahmed Riaz , Hussain Najaf , Safdar Muhammad Arslan , Ahmed Tausif
Published: February 2023

Background: Miserable status of health and public health is one of the major problems of more than 1 billion people living in slums across the world. Most of the governments, do not pay due attention. Purpose: Current study is especially devised to highlight the major problems of slum population in relation with health and public health so that better policy measures might be suggested. The second most populous city of Pakistan is Lahore and it is the home of about 27 million people, slums area of Lahore were chosen as population. Methodology: Through stratified sampling technique 250 households from ten slums were chosen as a sample. Inferential and descriptive statistical techniques have been used study in hand. The logistic regression model has been used to analyze the impact of important socio-economic variables on the health status of the family. Results: From descriptive analysis, we know that about 73 percent of the slum residents have no access to even basic health facilities, 32 percent of the slum children are not immunized, 72 percent of the slum women give birth to children without any proper assistance and 56 percent do not receive antenatal check – ups during pregnancy. Further, about 66 percent of the dwellers have no access to safe drinking water while majority face unhygienic and poor solid waste management status. Conclusion: The results of regression model shows that per capita income, education level of the family head, availability of safe drinking water and employment status of the family have positive while smoking and drinking leave negative impact on the health status of the dwellers. The findings address the authorities concerned to take holistic and practical measures for betterment of human development. Keywords: Slums, Antenatal Care, Basic Health Facilities, Safe Water, Immunization, Solid Waste Management
Efficacy and Safety of 5-Fluorouracil Cisplatin in Comparison with Gefitinib in Advanced and Recurrent Head and Neck Cancer
Authors: Baqai Tooba Imtiaz , Haider Ghulam , Anzar Javeria , Sehar Sana , Abro Nargis Aalam , Shah Aamera , Kumari Reeta , Haider Salar , Abbas Kiran
Published: February 2023

Background: The present study aimed to evaluate the efficacy and safety of Cisplatin plus 5-Fluorouracil in comparison with Gefitinib in advanced and recurrent head and neck cancer. Methods: A quasi experimental study was undertaken at the Department of Oncology, Jinnah Postgraduate Medical Centre between 2nd April 2022 and 2nd December 2022. All patients with histologically confirmed new or recurrent cases of head and neck cancer in the advanced clinical stage were recruited. Demographic data (age, gender, body mass index, comorbidity, etc.), medical history and clinical characteristics, routine biochemical analysis, urinalysis, and tumor assessments via CT scans and MRI, adverse effects and toxicity were recorded. Patients were divided randomly into two groups. Group A received Cisplatin plus 5-Fluorouracil while group B received Gefitinib monotherapy. The primary end point of the study was the overall response rate (ORR). Results: Complete response was demonstrated by seven (7.3%) and four (4.8%) individuals in Group A and B, respectively. Vomiting was significantly associated with Cisplatin plus 5-Fluorouracil with a frequency of 38 (39.58%) as compared to 10 (11.9%) in Group Gefitinib (p<0.001). Renal insufficiency was also experienced more frequently in Group A; 26 (27.1%) as compared to Group B; 2 (2.4%) (p<0.0001). Fever (p=0.004) and bone marrow suppression (p<0.001), loss of hearing (p=0.012) and skin rash (p<0.0001) were all significantly more frequently experienced by patients receiving Cisplatin plus 5-Fluorouracil as compared to those receiving Gefitinib. Conclusion: Gefitinib monotherapy was found to be more favorable for patients diagnosed with advanced head and neck cancer because oral mode of administration of Gefitinib alleviates the need for a hospital admission which makes it a more feasible option as compared to the alternatives. Furthermore, Gefitinib has a better safety profile and a relatively lower incidence of adv erse effects. Keywords: Cisplatin, Fluorouracil, Geftinib, Head Cancer, Neck Cancer, Recurrence.
Online Interviews During a Pandemic: Benefits, Limitations, Strategies and the Impact On Early Career Researchers
Authors: Brown Richard
Published: February 2023

In response to Covid-19, many universities and research institutions around the world suspended face-to-face interactions in preference for online research. Online data collection presents notable challenges for conducting qualitative interviews. This article discusses some key benefits and limitations to conducting interviews online compared to traditional face-to-face approaches. There is a need for up-to-date methodological guidance on conducting online interviews and balanced comparison between online and face-to-face methods. Moving research online in response to the pandemic is likely to have impacted the experiences of students and early career researchers, which may influence the direction of future qualitative research.
ANÁLISIS DE LOS EFECTOS Y CONSECUENCIAS DEL TRÁFICO DE TRABAJO EN LOS NIÑOS, NIÑAS Y ADOLESCENTES EN VENEZUELA
Authors: Yánez Da Silva María
Published: February 2023

El trabajo infantil es una violación de los derechos humanos fundamentales, que ha demostrado perjudicar el desarrollo de los niños, pudiendo conducir a daños físicos o psicológicos que les durarán toda la vida. Y en los peores casos, puede esclavizar a los niños, separarlos de sus familias, exponerlos a peligros y enfermedades graves y/o abandonarlos a su propia suerte en las calles de las grandes ciudades. En Venezuela, cada vez son mayores los casos de niños, niñas y adolescentes que suelen incorporarse al trabajo a edades tempranas, especialmente en las zonas rurales, dedicándose a actividades agropecuarias, al sector informal urbano y al servicio doméstico. En este sentido, la presente investigación tuvo como objetivo principal analizar los efectos y consecuencias del tráfico de trabajo de niños, niñas y adolescentes en Venezuela. El tipo de metodología empleada fue la investigación analítica, enmarcada en el diseño de Estudio analítico documental, siendo utilizada la revisión documental como técnica de recolección de datos. El proceso investigativo, permitió identificar que la práctica de las peores formas de trabajo Infantil trae consigo consecuencias sociales, morales, físicas, psíquicas y por último económicas. En Conclusión, los niños, niñas y adolescentes, son seres humanos más vulnerables de nuestra sociedad, quienes están en pleno crecimiento y desarrollo. Por lo que, para garantizar una generación de éxito para una sociedad, dependerá de la educación y el cumplimento de los derechos de los niños, niñas y adolescentes. Esta visión promueve un mundo de paz, tolerancia, equidad y de respeto por los derechos humanos.
LA NETNOGRAFÍA: UNA VÍA ALTERNA EN INVESTIGACIÓN ONLINE.
Authors: Liccioni Edith
Published: February 2023

El presente artículo pretende reflexionar en torno a la importancia que ha tenido el método etnográfico en la investigación social debido a que facilita técnicas de recolección de datos desde un enfoque cualitativo que favorece la interpretación, aspira a establecer una intervención en los debates actuales sobre el uso del método netnográfico para el estudio de los objetos digitales. Existe interés en el uso de la netnografía como herramienta para el estudio de la cultura digital, que apunta a una variación en la investigación y análisis de redes sociales para la representación gráfica de las relaciones sociales, dentro de diferentes redes partiendo de individuos. El diseño etnográfico requiere estrategias de investigación que conduzcan a la reconstrucción cultural.
El gerenciamiento híbrido y su impacto en el mundo empresarial. La gerencia vista desde la óptica de las nuevas tendencias organizacionales
Authors: Pinzón M María E.
Published: February 2023

El siguiente artículo se centra en la gerencia hibrida y su impacto en el mundo empresarial haciendo uso de los nuevos sistemas tecnológicos en esta era tecnológica.  Dando un breve inicio acerca de la presencia de lo hibrido en la gerencia se dará desarrollo a un aspecto esencial que va a desarrollar el tema en sí, adicionalmente como ha sido la gerencia y como ha sido el proceso de adaptación con las nuevas tecnologías que darán paso a los esquemas organizacionales y como motivan a dar uso de estas tecnologías para la toma de decisiones acertadas dentro de la organización. Con un contexto más claro se dará paso a las características fundamentales de la gerencia y su disertación, su enfoque y los análisis esenciales para dar comprensión al artículo. Posteriormente, se presenta la conclusión y la importancia del tema de manera general, dando cabida a las nuevas generaciones a que hagan uso de los vigentes aspectos tecnológicos en el ámbito organizacional y por lo tanto servir de material de apoyo para futuras investigaciones
Venezuela y el trabajo en tiempos de pandemia y postpandemia…una realidad que llegó para quedarse
Authors: Rodríguez Riera Francisco , Cruces María Elena
Published: February 2023

La presente investigación se realizó con el objetivo de estudiar las nuevas modalidades de trabajo surgidas en Venezuela a partir de la pandemia y post pandemia COVID 19, conocer las formas y características de cada una de ella, las reglas sanitarias que impactaron en el mercado laboral y las normas regulatorio en algunos países suramericano, A través de la hermenéutica se pretendió llegar a fundamentos ontológicos de la investigación, la cual estuvo enmarcada bajo la perspectiva cualitativa, en la que se utilizaron estrategias que permitieron revelar información pertinente y de calidad a través de fuentes primarias, constituidas en los espacios en que se estudió. La metódica se fundamenta en la fenomenología y la hermenéutica. Lo cual permitió la construcción teórica, como aporte al hecho educativo en las universidades. Se concluye en la investigación con la descripción de nuevas formas de trabajo que la crisis económica, social producto entre otro por la coyuntura política y sanitaria genero una suerte de imaginación del venezolano para la creación de las mismas aprovechando las oportunidades existentes del momento, tales como el llamado bachaquerismo, la raspa cupo, el cuidador de puesto en las filas, el cuidador de casas desocupadas entre otros. Siendo estos tipos de trabajos temporales.
Ética y responsabilidad social: Facultad de Ciencias Económicas y Sociales Universidad de Carabobo
Authors: Martínez Delia
Published: February 2023

La responsabilidad social universitaria (RSU), se asume  como una estrategia de gestión ética de los impactos que la acción universitaria en su cotidianidad genera hacia lo interno y externo, exigiendo de la institución responsabilizarse por las consecuencias sociales y medioambientales que ocasiona a sus grupos de  interés. Las universidades venezolanas en su largo transitar han puesto de manifiesto la responsabilidad social a través de prácticas tradicionales asociadas como: la extensión y servicio, voluntariado estudiantil, aprendizaje servicio, servicio comunitario, acciones que en la práctica han prestado un aporte social importante a las comunidades enmarcadas en su razón de ser. En la Universidad de Carabobo Facultad de Ciencias Económicas y Sociales (FACES UC), estas acciones  se cumplen según este enfoque tradicional. No alineado totalmente al nuevo concepto integrador, sistémico de gestión de impactos en sus ejes funcionales y entorno social que exige la RSU. Argumentos que sirvieron  de interés para abordar este trabajo, que tiene como objetivo general: Interpretar los conceptos de ética y responsabilidad social en ambientes de la FACES UC. Cuya metodología se orientó a un estudio documental cualitativo, hermenéutico reflexivo. Los resultados mostraron que la RSU es la herramienta de que dispone las universidades para implementar procesos de mejora continua, apoyada en el diálogo social y la rendición de cuenta para avanzar  hacia niveles de excelencia. Concluyendo que la ética sustentada en principios y valores conforman el eje central de gestión universitaria, que se visibiliza a través de la RSU aportando legitimidad institucional al igual que al conocimiento científico.
Prediction of growth performance parameters in the growing and free-range finishing phases of the Iberian pig via meta-analysis
Authors: SÁNCHEZ-ESQUILICHE Fernando , FERREIRA Chelo , RODRÍGUEZ-ESTÉVEZ Vicente , MUNIESA Ana
Published: February 2023

Aim of study: To describe and predict mathematically the growth parameters of Iberian pigs.
Area of study: Iberian dehesa agroforestry system. Southwest of Iberian Peninsula.
Material and methods: A quantitative and systematic review was carried out to find all studies with valid data of growth and finishing in the Iberian swine breed published up to May 2020. For the analysis of the data, a mathematical fitting model was obtained and a function was postulated to describe the relation between the variables age and body weight.
Main results: 112 publications were found, and after applying several quality filters, 18 with age and weight matched data were used. The database was composed of 76 different tests and 22,558 animals. The clasical growth phases were independently evaluated for data analysis.It was necessary to separate the finishing trials into three groups according to the starting age. Seven mathematical models were obtained for lactation,post-weaning, and montanera finishing. However, no valid test data were found during the growth and prefinishing phases. Besides that, a single model was obtained combining lactation and post-weaning, and another surface model including the variables age and weight to compare average daily weight gain in montanera finishing phase.
Research highlights: After systematic review of the studies that provide information on the growth of Iberian pigs, and a quantitative analysis, some mathematical linear and nonlinear models have been developed for the prediction of the production ratios at different phases.
Pitanga - desde a Serra da Pitanga a um município paranaense: um diagnóstico socioeconômico e geográfico
Authors: Rocha Diego da Luz , Jayme Naibi Souza , Fraga Nilson Cesar , Cavatorta Mateus Galvão
Published: February 2023

O presente trabalho busca traçar um diagnóstico sobre as condições socioeconômicas e outros aspectos geográficos do município de Pitanga. Para tanto, se fez necessário proceder, inicialmente, aos levantamentos históricos mais importantes, pois eles permitem vislumbrar o processo de formação socioespacial municipal. Foram feitos levantamentos de dados censitários no Instituto Brasileiro de Geografia e Estatística, no Instituto Paranaense de Desenvolvimento Econômico e Social, além de acervos encontrados no município de Pitanga estes como fontes primárias, assim como foram executados trabalhos de campo e utilização de literatura local e regional para entender o processo histórico de ocupação e organização da municipalidade.
Conflitos Territoriais Fronteiriços no século XIX: Contribuições para a formação de Minas Gerais
Authors: Santos Costa de Figueiredo Rafaela
Published: February 2023

A história da formação do território brasileiro é cercada por conflitos pautados na luta pelo território, afim de delimitar e expandir fronteiras. Minas foi cenário de conflitos territoriais ao longo do século XIX, pois, tratava-se de uma região estratégica, com saídas para São Paulo, Rio de Janeiro, onde a família real encontrava-se instalada e o Espírito Santo e seus afluentes das águas do Rio Doce. A partir desse contexto, o presente escrito apresentará alguns conflitos territoriais fronteiriços importantes para a formação dos limites do atual estado mineiro. Com isso, torna-se o objetivo geral analisar conflitos territoriais que influenciaram na formação do estado de Minas Gerais no século XIX, pautando-se em alguns objetivos específicos: identificar e descrever os conflitos territoriais em Minas Gerais; contextualizar a economia da época. Os conflitos serão descritos independentemente de sua importância política. Os elementos metodológicos que pautam o artigo basicamente se resumem na análise de artigos geográficos; históricos pertinentes ao tema, afim de descrever melhor o contexto territorial dos oitocentos, além de consultas a textos na Revista do IHGB[1]. Trata-se de uma pesquisa com enfoque teórico-bibliográfico, afim de contextualizar períodos e acontecimentos da época destacando alguns conflitos que contribuíram para a formação do estado mineiro atual.[1] Instituto Histórico Geográfico Brasileiro
DE UTOPIAS E DE TOPOI: ESPAÇO E PODER EM QUESTÃO (PERSPECTIVAS DESDE ALGUMAS EXPERIÊNCIAS DE LUTAS SOCIAIS NA AMÉRICA LATINA/ABYA YALA)
Authors: Porto Gonçalves Carlos Walter
Published: February 2023

Nesse artigo buscamos explicitar o silêncio acerca da relação espaço-poder que se dá tradicionalmente na tradição do pensamento ocidental, inclusive no campo do pensamento crítico. Mais do que falar de utopias queremos trazer ao debate a relação espaço-poder e não de modo abstrato, mas inspirando-nos em algumas experiências em curso de movimentos sociais na América Latina e, por isso, é da relação utopia-topoi que nos ocupamos. Procuramos colocar em diálogo o léxico téorico-político que emana dessas experiências latinoamericana com a tradição do pensamento/ação crítico europeu, sobretudo com o Marx tardio.
O CONTESTADO, SEU TERRITÓRIO, A POLÍTICA DE ASSISTÊNCIA SOCIAL: UM OLHAR SOBRE A GESTÃO
Authors: Martins Ana Claudia Vieira
Published: February 2023

O presente artigo integra a disciplina especial nominada Política Social: a lógica territorial na gestão das políticas sociais, do Programa de Pós-graduação em Serviço Social e Política Social da Universidade Estadual de Londrina-PR. Buscou-se descrever as percepções e apreensões no contexto vivenciado à luz dos conceitos de território, visando sobretudo, coadunar a experiência da viagem a campo no Contestado com o olhar na gestão das Políticas Sociais, dando ênfase à Política de Assistência Social.
A ampliação da escala geográfica: os estudos idiográficos e o trabalho de campo na Geografia
Authors: Francisco Alyson Bueno
Published: February 2023

Durante a trajetória do pensamento geográfico ocorre a fundamentação dos estudos por meio da escala regional. No entanto, nas últimas décadas a escala local está presente em inúmeras pesquisas na Geografia e o desenvolvimento das geotecnologias favoreceu o detalhamento das informações cartográficas. O trabalho de campo se destaca com metodologia fundamental para a Geografia diante da diversidade do espaço geográfico e as observações e descrições dos objetos de estudo, que estavam presentes nos estudos anteriores à sistematização da ciência geográfica, são necessárias para a representação real dos objetos. Os autores da Antiguidade como Erastótenes e Estrabão, as descrições das expedições realizadas por Humboldt e a Geografia corológica de Hettner na Alemanha do início do século XX, são exemplos da proposta metodológica do empirismo na Geografia. No campo da Geografia Física estão presentes os estudos de monitoramento dos fenômenos naturais e estes diagnósticos detalhados garantem as indicações das áreas a serem recuperadas dos impactos ambientais. Assim, nos últimos anos as grandes escalas estão presentes nos estudos geográficos.
SABERES E EXPERIÊNCIAS DO COTIDIANO ESCOLAR
Authors: Santos Sheila Castro dos , Coqueiro João Carlos Pereira
Published: February 2023

A perspectiva aplicada neste texto trata-se de uma pesquisa de viés qualitativa, bibliográfica e tipologia descritiva e explicativa, com os dados obtidos por meio de entrevistas das experiências de professores e gestores de escolas públicas. Com objetivo de evidenciar os números expressivos da evasão escolar, em conjunto com as medidas mitigadoras e políticas públicas que são aplicadas na Educação de Jovens e Adultos para um caminho de aprendizagem, conhecimento e inserção na plenitude da cidadania. Mostrando as diversidades dos atores envolvidos no ensino e aprendizagem escolar no município de Porto Velho. Ao utilizar as análises sobre a modalidade EJA, que no Brasil tornou-se no decorrer dos anos, ou sempre foi, algo tão complexo e desigual no país com especificidades e heterogeneidades sócio-culturais e político-econômicas distintas. Com contrastes significativos nas divisões orçamentárias e nas fiscalizações, que geralmente deixam a desejar e não evidenciam coerentemente onde os investimentos disponibilizados pelo Estado foram realmente aplicados. A compreensão desta ação, deve evidenciar a busca por uma compreensão enquanto interpretação criativa voltada o máximo possível para todo contexto experienciado por aqueles que praticam a docência, voltada para uma visão em favor de uma formação ética, auxiliando desta maneira os alunos que estão em busca de conhecimento, crescimento intelectual e profissional.
A ROÇA E O TRABALHO COLETIVO NA PRODUÇÃO DA FARINHA DE MANDIOCA NAS COMUNIDADES QUILOMBOLAS MATÁ E SILÊNCIO EM ÓBIDOS, PARÁ, BRASIL
Authors: Pontes Portela Leide Joice , Ribeiro dos Santos Priscila , Da Costa Silva Josué
Published: February 2023

Os quilombos Matá e Silêncio, localizados no município de Óbidos, Pará, partilham de uma economia de subsistência baseada no roçado e na produção da farinha de mandioca, tornando os dois quilombos semelhantes e próximos. Sendo a farinha de mandioca o pilar de sustentação do quilombo Matá e Silêncio, a mandioca permeia a sobrevivência, a sociabilidade, fortifica os laços afetivos dentro e fora dos núcleos familiares, restabelece as identidades e o sentimento de pertença tanto em relação ao território quilombola, quanto as práticas de trabalho coletivo. A partir das entrevistas fincadas na história oral realizadas nos dois quilombos, este artigo objetiva na compreensão do sentimento de pertença com a roça e com processo de produção da farinha de mandioca a partir do trabalho coletivo chamado de ‘puxirum’ nas referidas comunidades quilombolas.
Thiết kế bài học địa lý có sử dụng phương tiện nghe nhìn
Authors: Luyện Nguyễn Văn
Published: February 2023

Thiết kế bài học địa lý có sử dụng phương tiện nghe nhìn
Đến với khoa học
Authors: Hà Hoàng Thị Nhị
Published: February 2023

Đến với khoa học
ATIVISMO DIGITAL NA PANDEMIA DE COVID-19 NO BRASIL: DESAFIOS E POSSIBILIDADES
Authors: Londero Alessandra Staggemeier , Leite Martina Bravo , De Gregori Isabel Christine Silva
Published: February 2023

O início da Pandemia de Covid-19, em março de 2020, no Brasil, trouxe uma série de restrições a atividades, que precisaram se adaptar ou se reinventar neste período. Dentre elas, pode-se citar a participação política e o ativismo, que, em virtude do isolamento social, passou a se desenvolver de forma mais ativa no meio digital, com a utilização das redes sociais. Contudo, o cenário atual, marcado por forte polarização política, influência dos algoritmos e filtros “bolha” presentes nas redes sociais e a grande disseminação de notícias falsas, podem ser desafios ao exercício do ativismo digital. Assim, a presente pesquisa tem como objetivo compreender como o ativismo digital se estruturou na pandemia de Covid-19, e responder ao seguinte problema de pesquisa: quais os limites e possibilidades para o exercício do ativismo digital na pandemia de Covid-19? Para isso, foi utilizada na metodologia, o método de abordagem dedutivo, para, partindo de análises gerais sobre a construção teórica do ativismo digital, chegar a uma compreensão particular, sobre como se desenvolveram estas práticas durante o período pandêmico. Como método de procedimento, foi utilizado o método histórico com vistas a investigar o contexto histórico de desenvolvimento do ativismo digital no Brasil e no mundo, de modo a verificar a sua influência na sociedade atual, marcada pela Covid-19. A técnica de pesquisa utilizada documentação indireta, como levantamento de dados por pesquisa bibliográfica. As principais conclusões obtidas mostram que apesar do Brasil ser um país do Sul Global e ter muita desigualdade digital, durante o lockdown as pessoas encontraram na internet muito mais que um canal de informação, conseguiram manter o direito de manifestar seus anseios, inclusive sobre a própria pandemia.
Nghiên cứu giá trị thang điểm LIRADS bản 2018 trên CLVT trong đánh giá đáp ứng điều trị của ung thư biểu mô tế bào gan sau nút mạch bằng hạt vi cầu lần đầu
Authors: Nam Lê
Published: February 2023

Đại cương: Với ung thư tế bào gan (UTTBG), việc điều trị tại chỗ nói chung và nút mạch hóa chất (Transarterial chemotheraphy embolisation – TACE ) giúp cải thiện thời gian sống thêm, giảm giai đoạn và một số trường hợp là điều trị triệt căn. Phân loại LI- RADS về đáp ứng điều trị sau TACE đánh giá dựa trên phần ngấm thuốc của từng tổn thương u còn lại, LR-TR có tính khu trú và phù hợp để xác định còn u hoạt động hay không để nút mạch tiếp nếu còn chỉ định.

Mục tiêu: Nghiên cứu giá trị ứng dụng thang điểm LIRADS bản 2018 trên CLVT trong đánh giá đáp ứng điều trị của ung thư biểu mô tế bào gan sau nút mạch bằng hạt vi cầu.

Phương pháp: Nghiên cứu mô tả cắt ngang, hồi cứu phối hợp tiến cứu 29 BN được chẩn đoán UTTBG, được tiến hành nút mạch bằng hạt vi cầu tải hóa chất tại Trung tâm CĐHA Bệnh viện K Tân Triều và Khoa CĐHA Bệnh viện Hữu Nghị trong thời gian từ tháng 6/2021 – 9/2022. Được đánh giá lại về lâm sàng, AFP huyết thanh và CLVT ở thời điểm 1-3 tháng sau nút mạch.

Kết quả: Với 29 BN nút mạch bằng hạt vi cầu tải hóa chất, có tuổi trung bình 61,3 ± 11,03, nam/ nữ = 13,5/1. Đánh giá sau điều trị 1-3 tháng thấy tỷ lệ LR-TR không còn u là 44,8 %(13/29), đáp ứng lâm sàng tốt lên chiếm đa số với 28/29 BN, tỷ lệ có đáp ứng AFP sau điều trị là 31%. Mối liên quan về đáp ứng lâm sàng, đáp ứng AFP sau điều trị với phân loại LR-TR là không có ý nghĩa thống kê với p =0,552 và p=0,647.

Kết luận: Việc sử dụng thang điểm LIRADS về đánh giá đáp ứng điều trị trên CLVT của UTTBG sau nút mạch là phương tiện dễ sử dụng, phù hợp với thực tế lâm sàng và hữu ích cho các nhà can thiệp mạch.
ĐẶC ĐIỂM CỦA PHÌNH ĐỘNG MẠCH NÃO ĐỂ ĐÁNH GIÁ NGUY CƠ VỠ BẰNG SỬ DỤNG MÔ HÌNH HUYẾT ĐỘNG HỌC VÀ LƯU LƯỢNG DÒNG CHẢY BẰNG MÁY DSA.
Authors: Nguyễn Văn Hoàng , Vũ Đăng Lưu , Trần Anh Tuấn , Lê Hoàng Kiên , Nguyễn Quang Anh , Nguyễn Tất Thiện , Nguyễn Hữu An , Nguyễn Thị Thu Trang , Trần Trần Cường , Từ Đức Ngọc , Lê Hoàng Khoẻ , Nguyễn Thị Hảo , Vũ Thị Thanh , Phạm Minh Thông
Published: February 2023

Đo lưu lượng bên trong túi phình sử dụng nguyên lý dòng quang (OF – Optical Flow) kết hợp với mô phỏng động lực học chất lỏng CFD sử dụng phương pháp phân tích số (Numerical Analysis) là phương pháp mới giúp hiểu rõ hơn về dòng chảy bên trong mạch máu và túi phình cũng như các yếu tố về dòng vào, xoáy, phản lực làm tăng nguy cơ vỡ ở bệnh nhân có phình mạch não đã được chứng minh là liên quan mật thiết đến quá trình hình thành và phát triển của túi phình ngoài các yếu tố đã được đề cấp trong các nghiên cứu Meta – analysis trước đây như giới nữ, kích thước túi phình, vị trí như thông trước hay tuần hoàn sau, hút thuốc lá, tăng huyết áp, hình dạng túi phình,…

Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả tiến cứu thực hiện từ tháng 7 năm 2021 đến tháng 7- 2022, 127 bệnh nhân có phình mạch não được chụp DSA – AneurysmsFlow và điều trị tại bệnh viện Bạch Mai.

Kết quả: Tất cả 127 bệnh nhân với 170 túi phình trong đó 139 túi phình ở các vị trí khác nhau được đo lưu lượng dòng chảy bằng phần mềm thương mại Aneurysms Flow bằng máy hai bình diện tại bệnh viện Bạch Mai cho kết quả mô hình dòng chảy dòng tia vào chủ yếu tác động vào thành túi phình, thường xuyên nhất ở vị trí đáy (64,8%), hoặc thân (29,1%). Chỉ 15% số chứng phình động mạch có dòng chảy tác động vào cổ túi phình. Trên cơ sở phân loại của Cebral đơn giản hoá dựa vào dòng vào và hình thành các xoáy cũng như sự ổn định của các xoáy, dòng chảy loại I (57,6%) là phổ biến nhất, tiếp theo là loại IV (19,4%), loại II (12,2%) và loại III (10,8). Các mô hình xoáy ổn định đơn giản, vùng ảnh hưởng lớn và kích thước tia lớn thường được thấy với chứng phình động mạch không bị vỡ. Ngược lại, các túi phình động mạch bị vỡ có nhiều khả năng có mô hình dòng chảy bị xáo trộn, vùng ảnh hưởng nhỏ và kích thước dòng tia nhỏ.

Kết luận: Đo lưu lượng dòng chảy bằng máy DSA – Aneurysms Flow giúp hiểu một cách sâu hơn về sự biến động của dòng máu bên trong mạch mang và túi phình giúp cho việc cân nhắc điều trị sớm với nhưng túi phình có nguy cơ cao tránh biến chứng vỡ cũng như hiểu sâu hơn về huyết động học bên trong túi phình đã vỡ để có chiến lược điều trị.
Contest between leaders of the Ummah: Comparing civilizational populisms of PTI and TLP in Pakistan
Authors:   European Center for Populism Studies (ECPS), Batool Fizza , Yilmaz Ihsan , Shakil Kainat
Published: February 2023

With the recognition of populism emerging in varied forms across the Global South, the lacuna of research on populism in Asia is gradually filling. Yet, research on populism in Pakistan is still limited and focused mostly on the singular case of former Prime Minister Imran Khan and his political party Pakistan Tahreek-e-Insaaf (PTI). There is much lesser attention to the populism of Tahreek-e-Labbaik Pakistan (TLP), a far-right movement-turned-party. This paper addresses this gap by comparing the two cases of populism in Pakistan – PTI and TLP – to outline the similarities and differences in their characterization of “the people,” “the elite” and “the others,” using the framework of civilizational populism. The comparative analysis of public discourse of the leadership of two parties shows an extensive use of civilizational rhetoric by both parties, with varying degrees of religious sloganeering, to cater public support. Civilizational dimension forms an overlay over the vertical-horizontal dimensions of populism. Given that 2023 is the election year in Pakistan and both parties are planning to contest elections, this is a timely piece to warn about the treacherous trajectory taken by Pakistani politics.
Social Networks in the Modern World
Authors: Chaudhary Shreyam
Published: February 2023

In today's world, social networks are crucial. Information sharing is one of the key tasks carried out by this contemporary service. When I think back to the Arab uprising, I can remember how Twitter and Facebook were used to coordinate protests, notify participants of the date, time, and location, and emphasize the rallies' intended results. I've uncovered a lot of evidence to back up my claims, and I can now understand how Twitter and Facebook usage had a significant role in the emergence of the so-called Arab Spring. I came across the following quote while reading Huang's article "Facebook and Twitter vital to Arab Spring uprising: report": "Social networks played a critical role in mobilisation, empowering, sharing thoughts and influencing change”.
Nanoparticles in Pharmaceutical Science
Authors: HJ Yuktha , Kulkarni Gururaj S , Shetty Athmaja , Paarakh Padma M
Published: February 2023

The development of particle size reduction technologies over the past 30 years has transformed them from a research approach to an established commercial drug delivery platform. Since a growing number of research substances for poor aqueous solubility, nanotechnology methods have gained particular significance. The term "nanotechnology" refers to the development and application of materials whose components are, by standard, no larger than 100 nm in size. Nanotechnology investigates structural behavior at the molecular, and sub-molecular levels. It has the potential to transform several medical and biotechnology instruments and processes into ones that are transportable, less expensive, safer, and simpler to use. Nanoparticles are used for a variety of things, including medical treatments, energy storage in solar and oxide fuel batteries, optical devices, bactericidal agents, electronic devices, biological labeling, and in the treatment of some cancers. They are also widely incorporated into a variety of materials used in everyday life. This paper seeks to provide an overview of nanoparticles, paying attention to the current innovations and future aspects.
How Taxes of Local Governments Can Contribute to Climate Goals
Authors: Schep Arjen , Monsma Anneke , Kastelein Robert
Published: February 2023

How Taxes of Local Governments Can Contribute to Climate Goals

This article examines the roles (local) taxes can play in pursuing climate goals. The authors analyse the factors within the Dutch context which are limiting, and which are contributing to the effectiveness of the use of local taxes in the pursuit of climate goals. On the one hand, (local) taxes can serve their primary purpose: funding government spending, for example the creation of certain sustainable facilities. On the other hand, taxes can give a financial incentive to influence behaviour by improving the business case for sustainable solutions or make unsustainable behaviour more expensive or sustainable behaviour financially more attractive. This article presents examples of both funding sustainable facilities as of stimulating desired sustainable behaviour by means of a certain Dutch local tax measure. Despite the examples presented, we conclude that under the current legislative restrictions, in the Netherlands local taxes can play a modest role within the sustainability policy of local governments. The research into the current legal restrictions and possibilities for achieving climate goals with local taxes in the Netherlands leads to an analysis of insights that are also relevant outside the Dutch context.
Reply to my Critics
Authors: van der Walt Johan
Published: February 2023

Reply to my Critics

In this ‘reply to my critics,’ I engage with questions of institutional critique such as the critique of the depoliticising effect of the monetary practices of the European Central Bank (in response to Nikolas Vagdoutis), agonistic politics (in response to Manon Westphal), the enduring contingency of liberal democracy (in response to Hans Lindahl), the role of revolt and refusals to cooperate in liberal democracies (in response to Irena Rosenthal), the relation between the substantive norms and the actual ethics of liberal democracy (in response to Stefan Rummens), and times of regression and the strength and weakness of liberal democracy (in response to Ronald Tinnevelt).
Seksueel kindermisbruik en puberteit
Authors: Nijmeijers Lotte , Koning Anneke
Published: February 2023

Child sexual abuse and puberty – A systematic literature review on the relationship between child sexual abuse victimization and onset of puberty in girls

Early and late puberty pose a risk for many problems later in life. Various theories suggest that child sexual abuse victimization may either accelerate or delay the onset of puberty. This systematic literature review examines the relationship between child sexual abuse victimization and age of onset of puberty in girls. Fourteen scientific studies were included and analyzed. There is an association between child sexual abuse victimization and early age at menarche in girls, but there is insufficient evidence for an association with puberty onset in general. These findings may inform more effective prevention, identification, and assistance to victims of child sexual abuse.
STRATEGI MANAJEMEN SUMBER DAYA MANUSIA MELALUI PENINGKATAN PRODUKTIVITAS KERJA PEGAWAI NEGERI SIPIL KELURAHAN (Studi Kasus: Kelurahan Lenteng Agung, Kecamatan Jagakarsa, Kota Administrasi Jakarta Selatan, Provinsi DKI Jakarta)
Authors: Syauket Amalia , Cabui Cornelia Evelin
Published: February 2023

Pada penelitian ini, penulis menggunakan strategi manajemen sumber daya manusia dengan alat analisa SWOT, yakni analisa kekuatan, kelemahan, peluang dan ancaman yang dimiliki oleh kelurahan dalam meningkatkan produktivitas kerja pegawai negeri sipil. Dari hasil penelitian yang peneliti lakukan, ditemukan 4 faktor pendorong dan 4 faktor penghambat, yang didapat dengan melakukan teknik cross cek Triangulasi data. Faktor pendorong sebagai berikut: 1) Jaminan PNS (reward, punisment, remunerasi, gaji, tunjangan); 2)Fasilitas kelurahan yang memadai (via online); 3) Sosialisasi dari RT/RW dan Stakeholder; 4) Pemberdaayan melalui training, partisiapasi masyarakat sperti (baksos). Faktor penghambat sebagai berikut: 1) Rendahnya Sumber daya manusia yang mengatur tentang pelayanan; 2) Sarana prasaranan yang kurang memadai dalam memberikan pelayanan public; 3) Manajmen waktu belum ada; 4) Pengaruh lingkungan Masyarakat.Dari hasil perhitungan dengan melalui 8 tahapan analisa SWOT diketahui bahwa faktor kunci keberhasilan Kelurahan terdapat pada kuadran I dengan posisi 4,9 : 4,88. Strategi yang tepat adalah S – O (Strenghtopportunity) strategi, Meningkatakan jaminan PNS (Reward, punisment, Remunirasi, gaji, tunjangan) untuk pemberdayaan melalui training, partisipasi masyarakat seperti (baksos, seminar, loka karya).
Perbandingan Tugas dan Kewenangan Antara Dewan Perwakilan Daerah (DPD) dengan Senat Amerika Serikat: Sebuah Usulan Reposisi Peran DPD
Authors: Indrawan Jerry , Aji M. Prakoso
Published: February 2023

Peran Dewan Perwakilan Daerah (DPD) di Indonesia belum dikatakan optimal. DPD belum memiliki tugas dan kewenangan yang sama dengan kamar lainnya di dalam sistem bikameral Indonesia, yaitu Dewan Perwakilan Rakyat (DPR). Untuk melaksanakan prinsip memeriksa dan keseimbangan antara lembaga-lembaga tinggi negara, maka dibutuhkan perubahan radikal terhadap fungsi legislatif. Di Amerika Serikat, setiap kamar di Kongres, apakah itu Dewan Perwakilan Rakyat atau Senat, memiliki kewenangan untuk mengusulkan undang-undang terkait segala isu.

Sistem bikameral yang efektif hanya akan terjadi jika ada pengaturan total terhadap fungsi-fungsi legislasi. Karena itu, diperlukan Amandemen Undang-Undang Dasar 1045, khususnya Pasal 22D tentang DPD. Perubahan harus diinisiasikan dari atas, yaitu langsung dari Undang-Undang Dasar. Apabila Undang-Undang Dasar mendukung DPD, maka aturan dibawahnya sudah tentu akan mendukung DPD pula. Kondisi ini akan menyeimbangkan sistem legislatif di Indonesia antara DPD dengan DPR.
Importancia de la Actividad Agrícola y la Innovación Social en los Centros Públicos de Investigación: un Análisis Bibliométrico
Authors: Moreno-Ortiz Alba Lucía
Published: February 2023

Objetivo. Conocer el panorama mundial y nacional sobre investigaciones enfocadas en la Innovación Social a través de una bibliometría, como punto de referencia para promover estrategias en los Centros Públicos de Investigación (CPI) para la aplicabilidad en diferentes disciplinas del conocimiento, principalmente en las Ciencias Agrícolas. Metodología. Se utilizó la base de datos Scopus como una de las metodologías propias para estudios bibliométricos al reunir literatura científica con la temática “Social Innovation” con información recopilada en artículos publicados del 2015 - 2023. Hallazgos. Se obtuvo análisis bibliográfico relevante de la Innovación Social en sus distintas disciplinas, áreas, países con mayor numero de producción científica, y autores más representativos. Análisis bibliométrico para las Ciencias de la Agricultura y Biología. Originalidad. Estudio reciente y actualizado que contribuye a ampliar el estado del arte sobre el tema de Innovación Social. La búsqueda de este tema en la base de Scopus amplia la visión de su aplicabilidad en las diferentes disciplinas de la ciencia, producción internacional y nacional, participación de los centros de investigación y académicos. Información relevante sobre los artículos que abordan la Innovación Social en las Ciencias Agrícolas como guía para estudios futuros. Conclusiones y limitaciones. Este artículo genera un marco de referencia para futuros estudios de los CPI, universidades, sector público y privado, basado en estudios recientes enfocados en la teoría del cambio y la transformación como estrategia para resolver problemas sociales, más conocida como la Innovación Social. Este muestra los países con mayor producción científica, sus principales autores, producción por disciplinas del conocimiento y un enfoque más detallado de las investigaciones en el sector agrario tanto internacional como nacional, resaltando las universidades o centros de investigación con mayores publicaciones sobre el tema en México.
Dermatophytes and Other Infectious Microorganisms isolated from Hospital staff and Patients wearing Personal Protective Equipment (PPE) during COVID-19 era
Authors:   Department of Electrical/Electronic Engineering, Nigeria Defence academy, Kaduna, Aku D. E. , Airoboman A. E. , Shaibu A.
Published: February 2023

This work is aimed at assessing the voltage profile and losses of the 330kV Nigerian National Grid (NNG). In order to carry out this assessment, data was collated from the National Control Centre, Osogbo. Data collated include; Single Line Diagram (SLD), Line and Bus data. The network is made up of 23 PV buses, 41 PQ buses and 91 transmission lines. Newton Raphson technique was employed in performing the load flow analysis of the network in order to determine the voltage profile and losses associated with the network. Twenty (20) buses were found to be operating outside the acceptable limit of 0.95pu to 1.05pu with the highest voltage violation experienced at bus 16 with voltage profile of 0.8463pu. The real and the reactive power loss obtained were 3504.040MW and 4076.769MVAr respectively. All simulations were implemented in MATLAB software (version 2020b).
Voltage Profile and Losses Assessment of the 330kV Nigerian National Grid
Authors:   Department of Biology/Microbiology, Federal Polytechnic Nekede Owerri, Nigeria1, Chituru A. , Mbata T. I.
Published: February 2023

Hospital staff apparel contributed to the spread of microbial infections in susceptible individuals. A survey of presence of pathogenic microorganisms of public health importance in personal protective equipment (PPE) and wears used by hospital staff and patients in hospital in Owerri, Nigeria were carried out to determine the extent of contamination by clinically important microorganisms. A total of three hundred (300) swab samples of personal protective equipment and wears were used. The samples were analyzed and the presence of pathogenic microorganisms identified by swab culture and biochemical methods. The results obtained showed of a total of 300 swab samples of hospital staff apparel, 72 (24%) showed bacterial contamination including 32 (70%) of 46 samples from hand gloves, 28 of 45 (62%) samples from protective gowns, and 12 of 34 (35%) samples from face-shields. The bacteria isolated were Salmonella spp, Proteus vulgaris, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. 56 (19 %) showed fungal contamination including 31 (66 %) of 47 samples from protective gowns, 18 of 40 (45 %) samples from Hand gloves and 7 of 23 (30 %) samples from face-shields. Eight (8) different genera of fungi were recovered. They included Penicillium sp, Aspergillus fumigatus, Fusarium sp, Alternaria alternata, Rhizopus stolonifer, Microsporum canis, Trichophyton mentagrophytes and Candida albicans. Aspergillus species was the most predominant fungi species isolated. The isolation of clinically important microorganisms from the apparel suggests poor sanitary status and therefore the need for the existence of a health manual guide, which all staff should be obligated to follow, to improved infection control measures.
Norberto Castillo, O.P. on The Phases of Scientific Discovery as Model for a Tradition in Moral Enquiry
Authors:   University of Santo Tomas, Sagut Joel
Published: February 2023

This study is on the contribution of Rev. Fr. Norberto M. Castillo, O.P., a Filipino Dominican whose works in Philosophy of Science are treated in this article as important in responding to the challenge of building a ‘tradition in moral inquiry’ that was suggested by the works of Prof. Alasdair MacIntyre. The article will discuss Castillo’s three phases of a creative act: envisioning, invisioning and convisioning, and will use these phases as heuristic guide for the task of articulating a ‘tradition in moral inquiry.’ The study ends with the claim that the failure to arrive at a ‘tradition in moral inquiry’ is brought by the lack of a sustained reflection over moral matters which can only be achieved when an attempt to mimic the mentioned phases of scientific creative act is done in the field of moral philosophy.
Images of Dominican Saints and Blessed in the Philippines
Authors:   University of Santo Tomas, Trota Jose Regalado
Published: February 2023

The article is an attempt to highlight the role of the Dominicans in the history of Philippine art, which is more recognized in the field of architecture but much less in other media. With the exception of only a handful of pieces (a woodcut of San Pedro de Verona from Mexico, and maybe a couple of paintings perhaps from Spain), the works featured here were created in the Philippines for the use of Dominican missions and communities. Most of the artists were native Filipinos, although there are also some works by a few Chinese, Spanish, and even Italian artists. This is a reflection of the cosmopolitanism of Philippine society even in early modern times. It is a tantalizing glimpse into the variety of styles and materials used. Thus a second goal of the article is to provoke or inspire new Philippine iconography, informed with the models from the distant and recent Philippine past.