bluuebunny/crossref_metadata_2025 huggingface dataset:
Penerapan Digital Marketing Bagi Pemasaran Produk Kelompok Pemberdayaan Kesejahteraan Keluarga
Authors: Pradiptya Adhi , Kusumawati Citra Andriani , Ariefiantoro Teguh
Published: February 2025

The transformation of digital technology has affected the world of marketing, which directly helps MSMEs in increasing the effectiveness of business operations. However, the lack of skills and knowledge of the community, especially housewives in Tlogosari village in marketing their products, make the products not sold optimally. This community service program aims to help MSMEs adopt the use of digital technology in increasing the effectiveness of business operations. The community service program was conducted in the form of training for PKK groups in Tlogosari Kulon Village, Semarang City. The results of the activity showed that the PKK group experienced an increase in knowledge and use of digital marketing. This can be seen from the average results of pre-test and post-test, which shows that the increase in knowledge and understanding of MSMEs in the use of digital marketing is 97,3%. Therefore, this training is important to improve product marketing and attract consumers.
Cueva de la Vieja y arte rupestre de Alpera
Authors: Ruiz Juan F.
Published: February 2025

Este volumen, comienza por revisar el estado de conocimiento sobre las pinturas rupestres postglaciares conservadas en el término municipal de Alpera. En sucesivos capítulos se analiza su contexto local y regional, y se presentan las intervenciones de conservación llevadas a cabo en los últimos años. El análisis del arte rupestre, principalmente de Cueva de la Vieja, parte de la nueva documentación efectuada, describiendo la
totalidad de los registros gráficos de este yacimiento, y ofrece una lectura interpretativa a
partir de los resultados del nuevo calco.
Methodological and Practical Outlines for Development of the Noonomy Theory Study Course (Based on the Example of the Ural State University of Economics
Authors:   Ural State University of Economics, Pyankova S.G.
Published: February 2025

The paper outlines the key methodological principles of teaching the Noonomy study course using the experience of the Ural State University of Economics, aimed at the formation of high-quality knowledge, which contributes to the creation of a noohuman. The author examines the main documents regulating the conduct of educational activities in universities of the Russian Federation, analyzes the theoretical basis of the methodology specifics of modern teaching in higher education, as well as modern methods of organizing the educational process.
Exploring the Role of Assessment in Shaping Secondary Student-teacher Professionals in Limpopo Province
Authors: Badugela Thivhavhudzi Muriel
Published: February 2025

This qualitative research explored the intricate interplay between assessment practices and professional identity formation among student teachers. Professional identity, a multifaceted construct, is examined in the context of teacher education, focusing on unravelling the specific influence of assessment methods. Employing a qualitative approach through in-depth interviews, this study collected comprehensive data from a diverse cohort of student teachers in secondary schools in Limpopo Province. The research sought to identify how formative and summative assessments, feedback mechanisms, and evaluative criteria shape student teachers’ perceptions of themselves as emerging educators. By exploring the impact of assessment on key components of professional identity, including pedagogical beliefs, self-efficacy, and commitment to lifelong learning, the study provides nuanced insights into educational practices that deeply influence the identity formation process. Furthermore, the research explored the potential tension between standardised assessment practices and the individualised nature of teacher identity development. Perspectives from student teachers and mentors were central to elucidating the role of feedback and assessment in fostering a sense of belonging and efficacy within the professional teaching community. The findings will contribute significantly to the qualitative understanding of teacher education and assessment practices, offering valuable recommendations for refining evaluation methods that align with the holistic development of student teachers’ professional identities. The implications of this qualitative study extended beyond academia by providing insights to inform policy and practice and supporting the next generation of educators on their path to becoming proficient and reflective professionals.

Keywords – Assessment, Professional Identity, Student Teachers, Teacher Education
Let Peace Reign: Introducing Peace Education for Nigerian National Transformation
Authors: Ani Kelechi Johnmary
Published: February 2025

The increasing quest for peace in the globe is directly connected to the place of conflict, disaster and crisis in undermining the peace and good life of the masses. The impact of conflict in undermining national peace in the Nigerian state has remained problematic. This study thus focuses on the place of peace education in the quest for Nigerian national transformation. It used secondary data from literature to analyze the nature of peace education. Consequently, the study separated the nature of formal and informal peace education as well as the necessary topics that would be taught both in the formal and informal learning settings. It recommends the multiple paths to the transformation of the Nigerian peace research institutes as a way of promoting national peace, security and development. This study will contribute to the body of knowledge in the area of peace education and peacebuilding in Nigeria.

Keywords: Peace Education, Conflict, Peace Research, National Transformation, Nigeria
Evolution of X-Ray Gas in SN 1987A from 2007 to 2021: Ring Fading and Ejecta Brightening Unveiled through Differential Emission Measure Analysis
Authors: Sun Lei , Orlando Salvatore , Greco Emanuele , Miceli Marco , Chen Yang , Vink Jacco , Zhou Ping
Published: February 2025

As the nearest supernova (SN) observed since Kepler’s SN of 1604, SN 1987A provides an unprecedented opportunity to study in detail the early evolution of supernova remnants. Despite extensive studies through both observations and simulations, there is still an urgent need for a more effective approach to integrate the results from two sides. In this study, we conducted a detailed differential emission measure (DEM) analysis on the XMM-Newton observations taken in 2007 to 2021 to characterize the continuous temperature structure of SN 1987A, which can be better compared with simulations. The X-ray plasma exhibits a temperature distribution with a major peak at ∼0.5–1 keV and a high-temperature tail extending to ≳5 keV. The emission measure (EM) of the major peak started to decline around 2014, while the EM of the tail continued increasing and appears to have formed a secondary peak at ∼3–5 keV in recent years. Our DEM results are consistent with simulations, which help to further identify the major peak as originating from the equatorial ring and the secondary peak as arising from the newly shocked ejecta. Together with the simulations, our DEM analysis reveals recent fading of the ring and brightening of the ejecta in X-rays from SN 1987A. Additionally, we observed a recent decrease in the centroid energy of the Fe K line, providing further evidence of newly shocked ejecta.
A Survey of General Relativistic Magnetohydrodynamic Models for Black Hole Accretion Systems
Authors: Dhruv Vedant , Prather Ben , Wong George N. , Gammie Charles F.
Published: February 2025

General relativistic magnetohydrodynamics (GRMHD) simulations are an indispensable tool in studying accretion onto compact objects. The Event Horizon Telescope (EHT) frequently uses libraries of ideal GRMHD simulations to interpret polarimetric, event-horizon-scale observations of supermassive black holes at the centers of galaxies. In this work, we present a library of 10 nonradiative, ideal GRMHD simulations that were utilized by the EHT Collaboration in their analysis of Sagittarius A*. The parameter survey explores both low (SANE) and high (MAD) magnetization states across five black hole spins a
* = −15/16, −1/2, 0, +1/2, +15/16 where each simulation was run out to 30,000 GM/c
−3. We find the angular momentum and energy flux in SANE simulations closely matches the thin-disk value, with minor deviations in prograde models due to fluid forces. This leads to spin equilibrium around a
* ∼ 0.94, consistent with previous studies. We study the flow of conserved quantities in our simulations and find mass, angular momentum, and energy transport in SANE accretion flows to be primarily inward and fluid dominated. MAD models produce powerful jets with outflow efficiency >1 for a
* = + 0.94, leading to black hole spin-down in prograde cases. We observe outward directed energy and angular momentum fluxes on the horizon, as expected for the Blandford–Znajek mechanism. MAD accretion flows are sub-Keplerian and exhibit greater variability than their SANE counterpart. They are also hotter than SANE disks within r ≲ 10 GM/c
−2. This study is accompanied by a public release of simulation data at http://thz.astro.illinois.edu/.
Testing for Intrinsic Type Ia Supernova Luminosity Evolution at z > 2 with JWST
Authors: Pierel J. D. R. , Coulter D. A. , Siebert M. R. , Akins H. B. , Engesser M. , Fox O. D. , Franco M. , Rest A. , Agrawal A. , Ajay Y. , Allen N. , Casey C. M. , DeCoursey C. , Drakos N. E. , Egami E. , Faisst A. L. , Gezari S. , Gozaliasl G. , Ilbert O. , Jones D. O. , Karmen M. , Kartaltepe J. S. , Koekemoer A. M. , Lane Z. G. , Larson R. L. , Li T. , Liu D. , Moriya T. J. , McCracken H. J. , Paquereau L. , Quimby R. M. , Rich R. M. , Rhodes J. , Robertson B. E. , Sanders D. B. , Shahbandeh M. , Shuntov M. , Silverman J. D. , Strolger L. G. , Toft S. , Zenati Y.
Published: February 2025

The James Webb Space Telescope (JWST) is opening new frontiers of transient discovery and follow-up at high redshift. Here we present the discovery of a spectroscopically confirmed Type Ia supernova (SN Ia; SN 2023aeax) at z = 2.15 with JWST, including a NIRCam multiband light curve. SN 2023aeax lands at the edge of traditional low-z cosmology cuts because of its blue color (peak rest-frame B − V ∼ −0.3) but with a normal decline rate (Δm
15(B) ∼ 1.25), and applying a fiducial standardization with the BayeSN model we find the SN 2023aeax luminosity distance is in  ∼0.1σ agreement with ΛCDM. SN 2023aeax is only the second spectroscopically confirmed SN Ia in the dark matter–dominated Universe at z > 2 (the other is SN 2023adsy), giving it rare leverage to constrain any potential evolution in SN Ia standardized luminosities. Similar to SN 2023adsy (B − V ∼ 0.8), SN 2023aeax has a fairly extreme (but opposite) color, which may be due to the small sample size or a secondary factor, such as host galaxy properties. Nevertheless, the SN 2023aeax spectrum is well represented by normal low-z SN Ia spectra, and we find no definitive evolution in SN Ia standardization with redshift. Still, the first two spectroscopically confirmed z > 2 SNe Ia have peculiar colors and combine for a  ∼1σ distance slope relative to ΛCDM, though in agreement with recent SN Ia cosmological measurements.
La circulation générique d’une histoire : L’Oiseau bleu entre conte, lai et nouvelle
Authors: Mounier Pascale
Published: February 2025

L’étude des antécédents de L’Oiseau bleu, récit phare des Contes des Fées de Madame d’Aulnoy paru en 1697, montre que le récit merveilleux divertissant de type galant qui voit le jour à la fin du xviie siècle s’approprie et infléchit des récits configurés dans des contextes de production et de réception variés. Un parcours régressif conduisant du conte merveilleux classique au lai médiéval en passant par la nouvelle est susceptible de servir un questionnement méthodologique sur le rôle de la typologie des récits dans leur interprétation. D’un point de vue thématique, les différentes manifestations du type AT 432 « The Prince as Bird », trop souvent occultées par L’Oiseau bleu, demandent d’abord à être identifiées ; elles ont été produites sous forme orale ou écrite entre le xiie et le xviie siècle en France et en Italie. D’un point de vue narratologique, le contexte d’accueil offert par l’œuvre enchâssante, la quantité et le développement des épisodes et le traitement du registre merveilleux élaborent ensuite des visions différentes du rôle des capacités individuelles et des forces incontrôlables. D’un point de vue socioculturel, des transferts idéologiques manifestent enfin des conceptions variées de l’amour passion et du rôle social du couple. Chacune des six adaptations littéraires retrouvées propose ainsi selon le sous-genre qui est le sien − lai, novella aventureuse à sujet féerique, fabia ou conte de salon − une compréhension spécifique du substrat mythique de l’histoire.
Annexe I. Profession : conteur
Authors: Paillier Roxane
Published: February 2025

À partir de rencontres avec différents professionnels qui ont eu lieu en 2015 dans la région Ile-de-France (Évelyne Cevin, des bibliothécaires ayant reçu ou non une formation de conteur, des enseignants et le conteur professionnel Philippe Berthelot), nous observons quelles sont les éventuelles évolutions concernant l’usage du conte et ses pratiques en bibliothèque, en médiathèque, dans les écoles et dans les CDI (Centre de Documentation et d’Information).
Écrire, réécrire, mettre en dialogue des contes : l’exploration des portées éducatives du conte par Louise d’Épinay
Authors: Chiron Jeanne
Published: February 2025

Dans la seconde moitié du xviiie siècle, le conte littéraire a déjà une histoire de plus d’un siècle derrière lui. Pourtant, c’est à cette époque que son usage éducatif se met clairement en place, dans le souci de répondre à de nombreuses critiques, notamment celles de ce merveilleux qui ne serait pas compatible avec une éducation aux lumières de la raison. Le conte emprunte alors les voies de la simplification et de la moralisation, sous l’influence des conteuses pédagogues que sont Leprince de Beaumont et Genlis. À cette même époque, une voix moins connue mérite une attention particulière : Louise d’Épinay, écrivaine philosophe, propose une utilisation pédagogique des contes fort instructive. Dans un texte entièrement dialogué, Les Conversations d’Émilie, une mère soumet à sa fille des contes qui sont l’objet de discussions et de critiques. Elle part d’une suspicion à leur égard, nous présentant ainsi un témoignage de la réception des contes à cette époque, mais choisit de les utiliser tout de même, pour répondre au désir de la jeune Émilie. À cette fin, elle écrit plusieurs versions de deux types de contes, un conte moral et un conte merveilleux, afin de les exploiter au mieux pour servir à l’éducation intellectuelle de l’enfant : dans ces opérations de réécriture apparaissent les conditions d’utilisation de cette fiction suspecte. Le conte pourra alors servir d’exercice de lecture critique, en manipulant tous les ingrédients, langagiers, narratifs et imaginaires du conte de fées.
Penser l'avenir
Authors: Auzoult Laurent
Published: February 2025

Si le futur est indéterminé et relativement ouvert, il s’avère possible d’agir et de penser de façon à modifier les possibilités ou les préférences que nous élaborons vis-à-vis de l’avenir. Deux questions se posent alors : comment se structurent, évoluent les représentations de l’avenir et comment nos prédictions ou nos attentes s’actualisent-elles dans le futur ? Cet ouvrage répond à ces deux questions. Il traite des contenus et des processus conduisant à l’élaboration des représentations individuelles et collectives de l’avenir. Il aborde également la façon dont tout un chacun construit des projets, fait face à l’avenir à travers ses menaces et ses opportunités. À ce niveau, on considèrera les conduites humaines comme étant finalisées, orientées, intentionnelles et ancrées dans des contextes qui déterminent nos contenus de pensées et circonscrivent les possibles en matière d’action. Enfin, on évoquera quelques pratiques psychologiques pouvant relever de la prospection et de l’anticipation c’est-à-dire de la simulation dans trois champs d’application : l’accompagnement thérapeutique, l’orientation scolaire et professionnelle et la prévention en matière de santé.
Ethical Leadership and Its Communication Implications
Authors: Parchment Aundrae
Published: February 2025

The rapid advancement of technologies such as Artificial Intelligence (AI), robotics, and other systems within organizations can drive significant progress or lead to confusion and resistance if not introduced with effective leadership and communication. Without intentional and mindful strategy, communication, organizations risk negative outcomes beyond reputational and cultural damage. To successfully integrate new technologies and advance organizational strategies, there must be mindful and ethical leadership utilized with effective communication, change management, to maintain a culture of support as emerging technology parallels the introduction of a new team member. Proactive approaches to ethical leadership behaviors are crucial tools in mitigating dissatisfaction, preventing negative work cultures, and addressing incivility in the workplace in the era of new technological advancements.
Effect of Ecological Environments on Students' Metacognition and English Learning Performance of Secondary School Students of Badulla Educational Zone in Sri Lanka
Authors: Ekanayake E. M. S. D. , Priyanath H. M. S.
Published: February 2025

In literature, there is a dearth of studies exploring the influence of ecological factors on metacognition and English language learning performance, particularly in the context of secondary education in Sri Lanka. This study investigates how ecological factors influence metacognition and English language learning performance in secondary school students in Sri Lanka to fill these empirical and contextual knowledge gaps. The study used a quantitative method with a survey for collecting data, adhering to a positivist philosophy in a deductive approach. Primary data were collected from 290 secondary school students in the Badulla Educational Zone, Sri Lanka. A structured questionnaire was used to collect data and the data were analysed employing both descriptive statistics and the Partial Least Square Structural Equation Model (PLS-SEM). Key findings imply that ecological environments positively impact secondary students' English language learning performance and metacognition. The study further revealed that the metacognition of secondary school students has a significant influence on English language learning performance and the metacognition has a mediating effect on the relationship between ecological environments and the English language learning performance of secondary school students. Thus, the results imply that conducive ecological settings improve the English language learning performance of secondary school students. This further highlighted how crucial it is to promote metacognition and productive learning conditions to enhance the English language proficiency of secondary school students.
Management of atrial fibrillation: a practical and useful synopsis of last guidelines
Authors: Palareti Gualtiero
Published: February 2025

Atrial fibrillation (AF) is the most common arrhythmia and a disease of aging, as its prevalence increases in the elderly population, reaching approximately 10% in people aged 80 years and older. More than 66% of nearly 6,000 Italian AF patients included in a dedicated observational study were >75 years of age. AF is a strong independent risk factor for stroke due to thrombus formation in and embolization from the left atrial appendage. AF is associated with a fivefold increase in the risk of stroke, which tends to be more severe with higher mortality and disability than strokes in patients without AF. To reduce the risk of stroke or peripheral embolism, treatment with oral anticoagulants is recommended for most patients with AF.
Challenges experienced by Gauteng Foundation Phase departmental heads in managing teaching and learning
Authors: Mhlongo Asser R. , Chaane Tshidisegang M.
Published: February 2025

Background: The quality of teaching and learning depends on the school management team’s support and monitoring of teachers and learners to achieve the school’s objectives. Poor monitoring and lack of support compromise quality education.Aim: The study examined the challenges faced by Foundation Phase departmental heads in managing and monitoring teaching and learning processes at six primary schools in the Tshwane region.Setting: The study employed purposive sampling to select participants from six primary schools in the Tshwane West region, sampling six departmental heads of the Foundation Phase.Method: A qualitative research design was used to conduct the study. Fayol’s administrative management theory underpinned the study as its theoretical framework, and the interpretivist paradigm was used as the lens through which to view the phenomenon under study.Results: The study revealed that departmental heads are overworked regarding their responsibilities in the Foundation Phase.Conclusion: It is highly recommended that the Department of Basic Education (DBE) develop guidelines to streamline departmental heads’ responsibilities, prioritise core functions, delegate tasks and provide support mechanisms, like regular training, capacity-building programmes, and administrative assistance. Empowering teachers to take leadership roles can foster a culture of distributive leadership.Contribution: The study’s contributions include identifying specific challenges departmental heads encounter, emphasising the need for targeted support and training, and providing insights for education policymakers to improve teaching and learning outcomes and enhance the quality of education in the Foundation Phase.
Evaluating Hemagglutination Inhibition Antibody Titers as a Correlate of Protection for Influenza: A Sensitivity Analysis Based on Information Theory and Causal Inference
Authors: Ong Fenny , Molenberghs Geert , Callegaro Andrea , Van Der Elst Wim , Verbeke Geert , Stijven Florian , Van Keilegom Ingrid , Abad Ariel Alonso
Published: February 2025

Introduction:

Identifying hemagglutination inhibition (HI) antibody titers as a key immune correlate of protection (CoP) is crucial for developing, licensing, and monitoring the ongoing effectiveness of new influenza vaccines. Using a new statistical methodology, we explored the link between an inactivated quadrivalent influenza vaccine’s impact on HI antibody titers and its effectiveness against A/H1N1-associated influenza illness.

Methods:

We utilized data from a phase 3, observer-blind, randomized, controlled trial in children aged 6–35 months to assess HI antibody titers as an immune CoP. The assessment used a statistical method developed within a causal inference framework and a new information-theoretic metric of surrogacy, the so-called individual causal association (ICA).

Results:

The 75% and 85% uncertainty intervals of the ICA are 0.5511–0.8282 and 0.3632–0.8684, respectively, indicating a substantial reduction in the uncertainty about the vaccine’s effect on the absence of infection when its impact on the HI antibody titers is known.

Conclusions:

The evaluation yielded evidence supporting the validity of HI antibody titers as a CoP for influenza infection.
Efficacy of microwave ablation vs laparoscopic hepatectomy for primary small liver cancer: A comparative study
Authors: Li Huan-Song , Zhang Xuan-Feng , Fu Jun , Yuan Bo
Published: February 2025

BACKGROUND

In-depth comparative investigations in terms of clinical efficacies of liver tumor microwave ablation (MWA) and laparoscopic hepatectomy (LH), which are both important treatment modalities for liver neoplasms, have been limited in patients diagnosed with primary small liver cancer (PSLC).

AIM

To compare and analyze the clinical efficacy of liver tumor MWA and LH for PSLC.

METHODS

This study retrospectively analyzed the medical records of 123 patients with PSLC admitted to Xuzhou Central Hospital from January 2015 to November 2022 and categorized them based on treatment modalities into the LH and MWA groups. The LH group, consisting of 61 cases, received LH, and the MWA group, which included 62 cases, underwent liver tumor MWA. Basic data and various perioperative indicators were compared between the two groups, including changes in liver function indicators [alanine aminotransferase (ALT), glutamic aminotransferase (AST), and total bilirubin (TBIL)] pre- and post-treatment, and efficacy and postoperative complications were analyzed.

RESULTS

No statistically significant difference was observed between the two groups in terms of age, gender, tumor diameter, liver function Child-Pugh classification and number of tumors, body mass index, and educational status (P > 0.05). The overall effective rate was higher in the MWA group than in the LH group (98.39% vs 88.52%) (χ 2 = 4.918, P = 0.027). The MWA group exhibited less operation time, intraoperative bleeding, defecation time, and hospital stay than the LH group (P < 0.05). No difference was found in liver function indicators between the two groups pre-treatment (P > 0.05), and ALT, AST, and TBIL levels decreased in both groups post-treatment, with the MWA group demonstrating lower levels (P < 0.05). The MWA and LH groups exhibited postoperative complication rates of 4.84% and 19.67%, respectively, with statistically significant differences between the two groups (P = 0.012, χ 2 = 6.318).

CONCLUSION

MWA is more effective in treating PSLC, and it promotes faster postoperative recovery for patients, and more security improves liver function and reduces postoperative complications compared to LH.
Successful management of bleeding ectopic small bowel varices secondary to portal hypertension: A retrospective study
Authors: Xiao Nian-Jun , Chu Jian-Guo , Ning Shou-Bin , Wei Bao-Jie , Xia Zhi-Bo , Han Zhe-Yi
Published: February 2025

BACKGROUND

Bleeding ectopic varices located in the small bowel (BEV-SB) caused by portal hypertension (PH) are rare and life-threatening clinical scenarios. The current management of BEV-SB is unsatisfactory. This retrospective study analyzed four cases of BEV-SB caused by PH and detailed the management of these cases using enteroscopic injection sclerotherapy (EIS) and subsequent interventional radiology (IR).

AIM

To analyze the management of BEV-SB caused by PH and develop a treatment algorithm.

METHODS

This was a single tertiary care center before-after study, including four patients diagnosed with BEV-SB secondary to PH between January 2019 and December 2023 in the Air Force Medical Center. A retrospective review of the medical records was conducted. The management of these four patients involved the utilization of EIS followed by IR. The management duration of BEV-SB in each patient can be retrospectively divided into three phases based on these two approaches: Phase 1, from the initial occurrence of BEV-SB to the initial EIS; phase 2, from the initial EIS to the initial IR treatment; and phase 3, from the initial IR to December 2023. Descriptive statistics were performed to clarify the blood transfusions in each phase.

RESULTS

Four out of 519 patients diagnosed with PH were identified as having BEV-SB. The management duration of each phase was 20 person-months, 42 person-months, and 77 person-months, respectively. The four patients received a total of eight and five person-times of EIS and IR treatment, respectively. All patients exhibited recurrent gastrointestinal bleeding following the first EIS, while no further instances of gastrointestinal bleeding were observed after IR treatment. The transfusions administered during each phase were 34, 31, and 3.5 units of red blood cells, and 13 units, 14 units, and 1 unit of plasma, respectively.

CONCLUSION

EIS may be effective in achieving hemostasis for BEV-SB, but rebleeding is common, and IR aiming to reduce portal pressure gradient may lower the rebleeding rate.
Efficacy of water infusion combined with defoamers in colonoscopy
Authors: Li Jian , Chen Jun-Ping , Lai Chun-Han , Fu Lian , Ji Yong
Published: February 2025

BACKGROUND

Currently, colonoscopy still needs continuous optimization and exploration of novel alternative approaches to enhance the experience of patients during colonoscopy.

AIM

To analyze the efficacy of water infusion combined with defoamers in colonoscopy.

METHODS

This study included 97 patients undergoing colonoscopy from January 2024 to June 2024. The participants were categorized into two groups, namely, the control group (n = 47), who underwent conventional colonoscopy, and the experimental group (n = 50), who received colonoscopy using water injection combined with defoamers. A comparative analysis was then conducted on the disease detection rate (colonic polyps, colonorrhagia, colonic ulcers, colonic mucosal lesions, and others), colonoscopy duration, abdominal pain [visual analog scale (VAS)], Boston bowel preparation scale (BBPS), self-rating anxiety scale (SAS), bowel preparation comfort, complications (intestinal perforation, bleeding, nausea and vomiting, abdominal pain, and abdominal distension), and patient satisfaction.

RESULTS

The experimental group demonstrated a significantly higher total disease detection rate, BBPS scores, and patient satisfaction compared with the control group. Further, the research group exhibited shorter colonoscopy duration, lower VAS and SAS scores and total complication rate, and better patient comfort and satisfaction.

CONCLUSION

These results indicate that the combination of water injection and defoamers exhibited an overall better therapeutic effect than conventional colonoscopy, mainly reflected in higher disease detection rate, faster examination efficiency, lower abdominal pain, anxiety, and complication incidences, and significantly better bowel preparation, comfort, and patient satisfaction.
Coronary heart disease with pulmonary embolism: A case report
Authors: Xu Jun-Qing , Jiang Meng-Xin , Wang Feng , Yang Kai-Qiang , Xu Ying-Jiang , Wang Yu-Jiu , Dong Sheng-Jun
Published: February 2025

BACKGROUND

Coronary heart disease (CHD) and pulmonary embolism (PE) are thrombotic diseases. Patients with CHD and PE are common in clinical practice. However, the clinical diagnosis of PE is challenging due to overlapping primary symptoms, such as chest tightness and dyspnea. This confluence frequently leads to the misdiagnosis of PE, thus precipitating treatment delays and compromising patient outcomes. Herein, we report the case of a patient with both diseases who underwent surgery and medication therapy.

CASE SUMMARY

A 51-year-old man with a history of hypertension for 2 years visited a local hospital because of paroxysmal chest tightness for 1 d and was diagnosed with CHD. However, he refused hospitalization. He visited our hospital for the treatment of recurring symptoms. A comprehensive examination after admission revealed elevated D-dimer levels, and computed tomography pulmonary angiography was performed to confirm the diagnosis of PE. The patient successfully underwent coronary artery bypass grafting with anticoagulant and antiplatelet drugs and had a prognosis.

CONCLUSION

D-dimer is useful in screening for PE, whereas computed tomography pulmonary angiography is important for diagnosis. For patients with CHD and PE, coronary artery bypass grafting combined with anticoagulant and antiplatelet therapy is feasible.
Comprehensive understanding of a rare disease: Cardiac metastatic tumor, a double-center 10-year case review
Authors: Luo Ling-Yun , Yang Tian-Shu , He Zhen , Lin Li , Luo Xue-Lian
Published: February 2025

BACKGROUND

Cardiac metastatic tumors (CMTs) are rare yet pose significant medical concerns. Clinical studies on CMT are limited, particularly those involving multicenter data analysis.

AIM

To systematically analyze the etiology, sources, classification, treatment, and prognosis of CMT.

METHODS

A total of 226 CMT patients from two centers (2013 to 2023) were reviewed, and 153 tumor patients from China Health and Retirement Longitudinal Study were used as controls. The survival rates of 96 CMT patients were tracked through medical records and telephone follow-ups. Logistic regression and survival analyses were conducted to characterize CMT.

RESULTS

CMTs were predominantly male (67.26% vs 39.47%, P < 0.001). Intracardiac metastasis patients had worse heart and coagulation function than pericardial metastasis patients (prothrombin time: 13.90 vs 13.30, P = 0.002), D-dimer levels (2.16 vs 0.85, P = 0.001), B-type natriuretic peptide (BNP) levels (324.00 vs 136.50, P = 0.004), and troponin levels (5.35 vs 0.03, P < 0.001)). Lung and liver cancers were the predominant primary tumor types in CMT. Patients with lung cancer (76.40% vs 30.77%) and thymoma (7.45% vs 1.54%) exhibited a higher prevalence of pericardial metastasis, while those with liver cancer (35.38% vs 0.62%) showed a higher prevalence of intracardiac metastasis. Overall survival was better for pericardial metastasis than for intracardiac metastasis patients (median survival: 419 days vs 129 days, log-rank test P = 0.0029). Cox proportional hazards model revealed that advanced age [hazard ratio (HR) = 1.034, 95% confidence interval (95%CI): 1.011-1.057] and higher BNP and troponin levels (HR = 1.011, 95%CI: 1.004-1.018) were associated with worse survival. Surgery significantly improved the survival rate of patients. The median survival time was 275 days for patients who did not undergo surgery and 708 days for those who had surgery (log-rank test P = 0.0128)

CONCLUSION

Clinicians should consider CMT in the male lung or liver cancer patients with cardiac symptoms. Abnormal coagulation, impaired heart function, tumor location, and age are key prognostic factors for CMT. Surgical intervention is the preferred treatment option, as it significantly prolongs median survival.
Updates in breathomics behavior in ischemic heart disease and heart failure, mass-spectrometry
Authors: Marzoog Basheer Abdualah , Chomakhidze Peter , Gognieva Daria , Parunova Alena Yurievna , Demchuk Snezhana Nikolaevna , Silantyev Artemiy , Kuznetsova Natalia , Kostikova Anastasia , Podgalo Dmitrii , Nagornov Evgeny , Gadzhiakhmedova Aida , Kopylov Philipp
Published: February 2025

BACKGROUND

Cardiovascular disease (CVD) and associated sequalae remain the leading cause of disability worldwide. Ischemic heart disease (IHD) and heart failure are the most common etiologies of morbidity and mortality worldwide. This is due to the poor diagnostic and management methods for heart failure and IHD. Early detection of related risk factors through modern strategies is underestimated and requires further research.

AIM

To interpret data from the published literature on volatile organic compounds (VOC), including all the methods used to analyze exhaled breath in patients with IHD and heart failure.

METHODS

Searches for specific keywords were performed on Scopus and PubMed. A total of 20 studies were identified in breath analysis and IHD and heart failure. The study is registered in PROSPERO (Registration No. CRD42023470556).

RESULTS

Considering the articles found, more research is required to gain a full understanding of the role of VOCs in IHD and heart failure. However, the existing literature demonstrates that cardiac metabolic changes can be expressed in exhaled air. The number of papers found is extremely low, making interpretation extremely difficult.

CONCLUSION

Exhaled breath analysis can be a novel biomarker for the diagnosis and prevention of heart failure and IHD. Exhaled breath analysis can be used as a mirror to reflect the metabolic changes related to IHD and heart failure.
Red blood cell distribution width to albumin ratio is correlated with prognosis of patients in coronary care unit
Authors: Wang Jiao-Ni , Hu Ze-Song , Yu Yong-Wei , Peng Xiao-Hui
Published: February 2025

BACKGROUND

As red blood cell distribution width (RDW) and albumin have been shown to be independent predictors of mortality from various diseases, this study aimed to investigate the effect of the RDW to albumin ratio (RA) as an independent predictor of the prognosis of patients admitted to the coronary care unit (CCU).

AIM

To use the RDW and albumin level to predict the prognosis of patients in the CCU.

METHODS

Data were obtained from the Medical Information Mart Intensive Care III database. The primary outcome was 365-day all-cause mortality, whereas the secondary outcomes were 30- and 90-day all-cause mortality, hospital length of stay (LOS), and CCU LOS. Cox proportional hazards regression model, propensity score matching, and receiver operating characteristic curve analyses were used.

RESULTS

The hazard ratio (95% confidence interval) of the upper tertile (RA > 4.66) was 1.62 (1.29 to 2.03) when compared with the reference (RA < 3.84) in 365-day all-cause mortality. This trend persisted after adjusting for demographic and clinical variables in the propensity score-matching analysis. Similar trends were observed for the secondary outcomes of hospital and CCU LOS. Receiver operating characteristic curve analysis was performed by combining the RA and sequential organ failure assessment (SOFA) scores, and the C-statistic was higher than that of the SOFA scores (0.733 vs 0.702, P < 0.001).

CONCLUSION

RA is an independent prognostic factor in patients admitted to the CCU. RA combined with the SOFA score can improve the predictive ability of the SOFA score. However, our results should be verified in future prospective studies.
Left bundle branch pacing cardiac resynchronization therapy vs biventricular pacing cardiac resynchronization therapy–time to write a requiem for biventricular pacing-cardiac resynchronization therapy
Authors: Pradhan Akshyaya , Saggu Daljeet , Bhandari Monika
Published: February 2025

Cardiac resynchronization therapy (CRT) reduces heart failure (HF) hospitalizations and all-cause mortality in patients with HF with reduced ejection fraction with left bundle branch (LBB) block. Biventricular pacing (BVP) is considered the gold standard for achieving CRT; however, approximately 30%–40% of patients do not respond to BVP-CRT. Recent studies have demonstrated that LBB pacing (LBBP) produces remarkable results in CRT. In this meta-analysis, LBBP-CRT showed better outcomes than conventional BVP-CRT, including greater QRS duration reduction and left ventricular ejection fraction improvement, along with consistently lower pacing thresholds on follow-up. Additionally, there was a greater reduction in New York Heart Association class and brain natriuretic peptide levels. This study contributes to the growing body of encouraging data on LBBP-CRT from recent years. With ongoing technological advancements and increasing operator expertise, the day may not be far when LBBP-CRT becomes the standard of care rather than the exception.
Heart failure with preserved ejection fraction and metabolic dysfunction-associated steatotic liver disease: Twin challenges, one metabolic solution
Authors: Lian Li-You , Huang Chen-Xiao , Chen Qin-Fen , Zhou Xiao-Dong
Published: February 2025

Heart failure (HF) with preserved ejection fraction (HFpEF) has exceeded HF with reduced ejection fraction (HFrEF), becoming the most common type of HF. Unlike HFrEF, HFpEF is primarily a chronic low-grade inflammatory process closely associated with metabolic disorders. The coexistence of HFpEF and metabolic dysfunction-associated steatotic liver disease (MASLD) presents significant clinical challenges due to shared metabolic pathophysiology and complex interplay. Management strategies for HFpEF and MASLD remain challenging. Sodium-glucose cotransporter 2 inhibitors have shown benefits in managing both conditions. Additionally, glucagon-like peptide-1 receptor agonists are being actively investigated for their potential benefits, particularly in MASLD. A comprehensive, patient-centered approach that combines metabolic and cardiovascular care is essential for improving outcomes in patients with HFpEF and MASLD, addressing the global metabolic health challenges.
Wykłady, seminaria i studenci Adama Skałkowskiego (1877– 1951)
Authors: Łukasiewicz Dariusz
Published: February 2025

Niezbyt często dysponujemy dobrymi materiałami biograficznymi nt. historyków. Łatwiej odtworzyć ich poglądy i prowadzone przez nich badania naukowe na podstawie piśmiennictwa. Lepiej jest w wypadku Adama Skałkowskiego (1877–1951). Zachowały się jego wspomnienia, dosyć obfita korespondencja i spuścizna. Dzięki pisanym ręką wykładom uniwersyteckim i rękopisom wykładów powszechnych można odtworzyć działalność profesora jako wykładowcy. Są relacje opisujące styl prowadzonych przez niego wykładów. Korespondencje i inne materiały dają wgląd także w jego seminarium magisterskie i doktorskie, opiekę nad uczniami i w egzaminy. Listy pozwalają śledzić duże zaangażowanie mistrza w pomoc podopiecznym, personalne relacje z uczniami. Widoczna jest nie tylko opieka naukowa, lecz także prywatna, organizowanie wyjazdów stypendialnych i kwerend archiwalnych (listy polecające), a nawet wspieranie finansowe. Otrzymujemy bardzo interesujący obraz pracy uczonego pierwszej połowy XX w. w zupełnie innym niż obecnie systemie wykładów, egzaminów i relacji ze studentami i studentkami. Wykłady miały charakter wyłącznie monograficzny i związane były z bieżącą pracą naukową profesora, tak było również w wypadku innych historyków. Było tylko 5 egzaminów kursowych: z nauk pomocniczych, historii starożytnej, średniowiecznej, nowożytnej oraz filozofii. Egzaminy nie miały nic wspólnego z wykładami i materiał kursowy trzeba było uzupełnić z podręczników.
Prefazione
Authors: Falvay Dávid , Szemere Ditta
Published: February 2025

Prefacio del volumen monográfico.
Coordinadores:

Falvay Dávid
ELTE Department of Italian Language and Literature.
Szemere Ditta
ELTE Department of Italian Language and Literature.
Understanding the Preparation of Guidance and Counseling Programs
Authors: Habsy Bakhrudin All , Atsila Butsaina Altaf , Salsabila Qonita , Fitriano Lino , Melati Shella
Published: February 2025

The development of guidance and counseling program is a complex process tha requires systematic planning. This study aims to examine the process of developing gudance and counseling program trough a literature rivew approach. The research employs a qualitative method with a literature rivew design. A literature review is a research method conducted by collecting, reviewing, and analyzing existing information from various relevant sources such as scientific journals, books, articles, and previous research reports. The result of this study Include the following: (1) Components of guidance and couseling programs, (2) Types of gudance and counseling programs, (3) Factors to consider in developing gudance and counseling programs, (4) requirements for developing guidance and counseling programs, (5) Stages of developing gudance and counseling programs, and (6) The structure of the gudance and counseling service implementation plan.
Demandas de distancia recorrida en campo exigidas en partidos de fútbol profesional: una revisión sistemática
Authors: Estévez Planas Pau , Planas Anzano Antoni , Matas Garcia Sergi , Puigserver Bennassar Pedro , Albesa Albiol Lluís , Pajón Moreno David
Published: February 2025

Introducción y objetivo: El fútbol es un deporte colectivo en constante evolución que en los últimos años ha incrementado el interés por las capacidades condicionales de los jugadores debido a su posible relación con el rendimiento deportivo. Conocer las demandas exigidas por la competición permite mejorar el diseño y periodización de los entrenamientos. El objetivo principal de este trabajo fue explorar y analizar las demandas físicas soportadas por los jugadores profesionales de fútbol en competición en los últimos años, centrándose en variables de distancia recorrida en campo.
Metodología: Siguiendo las pautas de la declaración PRIMSA se realizó una revisión sistemática con las bases de datos de Sportdiscuss, PubMed y Scopus. Se incluyeron aquellos estudios relacionados con las demandas de distancias absolutas recorridas por los jugadores en partidos de fútbol FIFA masculino profesional y en los que se expresaran los resultados en colectivos y por posiciones. Se seleccionaron 17 estudios y se evaluó su calidad metodológica con la herramienta ROB 2.0.
Resultados y conclusiones: Los resultados muestran que los jugadores recorren una media de 10289,20m de distancia total por partido siendo los mediocentros los jugadores que mayor distancia recorren. Al mismo tiempo se encontró que los jugadores recorren una mediana de 501m de distancia a alta velocidad, siendo los jugadores exteriores y/o los delanteros los que obtuvieron mayores velocidades.
Les deux pièges à animal découverts à Mari (Syrie, fin du IIIe et début IIe millénaire av. J.-C.) et leur place dans la production d’autres sites antiques
Authors: Weygand Isabelle
Published: February 2025

Résumé :

Deux pièges à animal ont été découverts sur le site de Mari/Tell Hariri en Syrie, l’un datant de la fin du IIIe millénaire et le second du début du IIe millénaire av. J.-C. dans des contextes d’habitation. Ils sont étudiés ici et replacés dans la production d’une vingtaine d’objets antiques de même vocation : ils proviennent d’une vaste aire géographique (de la vallée de l’Indus jusqu’en Méditerranée orientale) et leur datation s’échelonne depuis le début du IIIe millénaire jusqu’au Ier millénaire av. J.-C. Leur dessin à la même échelle permet de les comparer aisément et de dégager des points communs ou des spécificités. Cette catégorie d’objets, souvent mal interprétés par les fouilleurs, est déjà mentionnée dans les textes antiques mésopotamiens, elle concerne les préoccupations de la vie quotidienne.

Abstract:

Title: Two animal traps discovered at Mari (Syria, end of the 3rd millennium and beginning of the 2nd millennium BCE) and their place in the production of other ancient sites

Two animal traps have been discovered in habitation contexts at the Mari/Tell Hariri site in Syria, one dating from the end of the 3rd millennium BCE and the second from the beginning of the 2nd millennium BCE. They are studied here and replaced in a production of about twenty other antique objects: they come from a very large geographical area (from the Indus Valley to the eastern Mediterranean) and their dating ranges from the beginning of the third millennium up to the first millennium BCE. Their representation on the same scale makes it possible to easily compare them and to identify common points or specificities. This kind of objects, often misinterpreted by excavators, is already mentioned in ancient Mesopotamian texts: they illustrate worries of daily life.
Une interprétation de conduits énigmatiques à Mari : faire passer à travers les murs des animaux chasseurs de rongeurs, comme des mangoustes
Authors: Laroche-Traunecker Françoise
Published: February 2025

Résumé :

En 1999 et en 2000, les fouilles de Mari ont mis au jour, dans le quartier dit « du souk », de curieuses installations reliant les pièces des boutiques les unes aux autres par groupes de quatre. Il s’agit de conduits en plâtre de diamètres variables qui traversent les murs et se terminent, dans les angles des pièces, par des sortes de plates-formes creuses. Nous proposons de les interpréter comme un système permettant à un animal apprivoisé ou dressé de guetter et de chasser les rats et les souris qui s’attaquaient aux produits (céréales, farine, etc.) entreposés dans les arrière-boutiques. Nous avançons l’hypothèse de l’utilisation de mangoustes pour accomplir cette tâche.

Abstract:

Title: Enigmatic pipes in Mari, an interpretation: let pass through the walls rodent-hunting animals, like mongooses

In 1999 and 2000, the excavations of Mari brought to light, in the so-called “souk” area, curious installations connecting the rooms of the shops to each other in groups of four. These are plaster pipes of varying diameters which cross the walls and end, in the corners of the rooms, in sorts of hollow platforms. We propose to interpret them as a system allowing a tamed or trained animal to watch for and hunt rats and mice that attacked products (cereals, flour, etc.) stored in stockrooms. We hypothesize the use of mongooses to accomplish this task.