bluuebunny/crossref_metadata_2025 huggingface dataset:
Do commercial dog extracts cross-react with Felis domesticus allergen 1
Authors: Hellu Tasha , Gomez Robert , Weiss Samuel , Smith Derek , Steigelman Daniel
Published: November 2024

Background: Half of U.S. households own a dog despite 10% of individuals being sensitized to dog. Assessment and treatment options for dog allergy include the use of commercial dog extracts which have inconsistent performance, making diagnosing and managing dog allergy challenging.
Contamination of dog extracts with other allergens has previously been reported. Objective: We sought to determine whether commercial dog extracts contain other aeroallergens. Methods: An extract purity and quantification study on acetone precipitated
dog hair and dander extract (AP dog) was performed, 6 aeroallergens; Alternaria (Alt a 1), Ragweed (Amb a 1), German Cockroach (Bla g 2), Dust Mite (Der p t), Cat (Fel d 1), and Rye Grass (Lol p 1). Following, conventional dog hair and dander extract (CV dog) and the new ultrafiltered dog
hair and dander extract (UF dog) were also assessed based on the initial results of AP dog. SDS-PAGE was performed on all three dog extracts to compare allergen content. Lastly, serology results and aeroallergen immunotherapy prescriptions were compared. Results: The ELISA
trays with Alt a 1, Amb a 1, Bla g 2, Der p 1, and Lol p 1 antibodies did not capture AP dog, while the ELISA tray with Fel d 1 antibody captured AP dog, CV dog, and UF dog. SDS-PAGE results of the 3 dog extracts did not reveal a band at the molecular weight for Fel d 1. Conculsion:
Contamination of commercial dog extracts was not found. However, our findings are supportive of commercial dog extracts containing a Fel d 1-like dog allergen that is cross-reactive to Fel d 1. Cross-reactivity between commercial dog extracts and Fel d 1 could be responsible for double
positivity to cat and dog in serology. Additional studies are needed to better illustrate this Fel d 1-like dog allergen.
Clinical audit on postpartum hemoglobin levels: A study on postpartum anemia
Authors: John Jennifer , Arsha A. R. , Balamurugan Shalini , Thomas Tresa Remya Athipozhi , Sweta Kulkarni , Kasilingam Poovizhi , Pasupathy Sanjay
Published: November 2024

Objectives:

The present study was carried out to assess the prevalence of anemia with reference to the Hb levels during postpartum period. The study also investigates the influence of age and mode of delivery on postpartum Hb levels.

Material and Methods:

It is a hospital-based retrospective descriptive study. The postpartum patients’ data were obtained from the medical records department of a tertiary care hospital. Data of the patients registered for routine blood investigation in the period of December 2023 to January 2024 were collected from the records. Based on patient’s hospital ID, other details including age, Hb level, and mode of delivery data were obtained. Statistical analysis was performed to check the effect of age and mode of delivery on postpartum Hb level by Pearson correlation using IBM Statistical Package for the Social Sciences Statistics version 24.0.

Results:

About 64.3% of the patients belonged to the age group of 20–30 years and remaining 35.7% within 30–40 years. The percentage of postpartum patients who underwent lower segment cesarean section (LSCS) and normal vaginal delivery (NVD) were 85.7% and 14.3%, respectively. However, cumulative percentage of NVD was higher (100%) than LSCS (85.7%). The postpartum Hb level ranged from 7.9 to 15.2 g/dL. About 54% of patients showed moderate anemia (8–10.9 g/dL), followed by 24% mild (11.9–11 g/dL) and 2% with severe anemic (<8 g/dL) condition.

Conclusion:

The study highlights the prevalence of PPA associated with both LSCS and NVD modes of delivery. Although the number of anemic patients was higher in LSCS (48) compared to NVD (8), the percentage remains the same at 80% each considering the total number of patients in each category. These observations point out the risk of high-volume blood loss associated with both modes of delivery and emphasize the need for adopting precautionary measures.
Pengaruh Pendidikan Kesehatan Menggunakan Leaflet Berbahasa Daerah terhadap Tingkat Pengetahuan Penderita Hipertensi di Desa Lambanan Kabupaten Mamasa
Authors: Nurfadhila Nurfadhila , Wahab Masyitah , Mae Mae
Published: November 2024

Pendidikan kesehatan merupakan bagian dari upaya kesehatan yang bertujuan meningkatkan pola hidup serta memberikan pengetahuan terutama bahaya penyakit hipertensi beserta cara pencegahannya. Tujuan penelitian untuk mengetahui pengaruh pendidikan kesehatan menggunakan leaflet berbahasa daerah terhadap tingkat pengetahuan penderita hipertensi di Desa Lambanan Kabupaten Mamasa. Desain dalam penelitian ini adalah quasy experiment dengan rancangan penelitian one group pre-post test dengan besaran sampel 31 orang. Pengumpulan data dilakukan dengan menggunakan kuesioner culturally adapted hypertension education (CAHE) dan berlangsung selama 2 minggu di bulan Agustus 2024. Hasil penelitian ini menunjukkan kelompok pre test dengan nilai rata-rata 6.42 yang tergolong mempunyai skor pengetahuan yang rendah pada kelompok post test dengan nilai rata-rata 9.48 yang tergolong mempunyai skor pengetahuan baik. Kesimpulan yaitu hasil dari penelitian ini menunjukkan dengan nilai p-value 0,000<0,05. Pendidikan kesehatan menggunakan leaflet berbahasa daerah dapat dijadikan alternatif dalam meningkatkan pengetahuan penderita hipertensi.
Моделирование структурНЫХ особенностей СИСТЕМЫ микросвитков диоксида титана С C-Auлегированием
Authors: Д.Н. Бухаров , А.О. Кучерик , В.Д. Самышкин , А.Ф. Лелекова , С.М. Аракелян
Published: November 2024

Приведены результаты экспериментального синтеза системы микросвитков диоксида титана с Au наночастицами, полученные оригинальным трехэтапным методом синтеза. Приведена оценка размеров и фрактальных размерностей полученных образцов. Для описания структуры полученных образцов предложена имитационная модель в приближении клеточного автомата и диффузионно-ограниченной агрегации в рамках окрестности Неймана. Предложена модель торцевого сечения микросвитка в приближении спирали Архимеда с учетом шероховатости, определяемой в рамках диффузионного приближения, реализованного с использованием техники клеточного автомата. Для описания массива микросвитков применялось приближение диффузионно-ограниченной агрегации. Полученные величины погрешности моделирования свидетельствовали о применимости предложенных моделей для описания систем микросвитков в первом приближении.

The results of the experimental synthesis of a system of titanium dioxide micro-scrolls with Au nanoparticles obtained by the original three-stage synthesis method are presented. An estimate of the sizes and fractal dimensions of the obtained samples is given. To describe the structure of the obtained samples, a simulation model is proposed in the approximation of a cellular automaton and diffusion-limited aggregation within the Neumann neighborhood. A model of the end section of a microscroll in the Archimedes spiral approximation is proposed, taking into account the roughness determined within the framework of the diffusion approximation implemented using the cellular automaton technique. The diffusion-limited aggregation approximation was used to describe the array of micro-scrolls. The obtained values of the modeling error indicated the applicability of the proposed models to describe microsсroll systems in the first approximation.
ОСОБЕННОСТИ ВЗАИМОДЕЙСТВИЯ ГИПОФОСФИТА КАЛЬЦИЯ С ПЕРХЛОРАТОМ КАЛИЯ
Authors: А.Л. Верещагин , Е.Д. Минин , Н.В. Бычин , А.В. Сергиенко , С.С. Титов , Н.В. Титова
Published: November 2024

Методом синхронного термического анализа исследован процесс взаимодействия перхлората калия с гипофосфитом кальция до температуры 600 °C. Установлено, что взаимодействие протекает через две экзотермические стадии в 3,55 и 1,97 кДж/г. Термическое разложение смеси состоит из двух стадий – после фазового перехода перхлората калия на первой стадии происходит его частичное взаимодействие с образованием фосфида кальция, который потом затем во второй стадии окисляется при температуре плавления перхлората калия. Методами оптической микроскопии и рентгенофазового анализа изучен состав образовавшихся конденсированных продуктов. Установлено, процесс взаимодействия смеси гипофосфита кальция с перхлоратом калия происходит в две стадии, сопровождается выделением аэрозоля фосфорной кислоты и хлорида калия, при этом образуется конденсированная фаза из фосфатов кальция и хлорида калия.

The process of interaction of potassium perchlorate with calcium hypophosphite up to a temperature of 600 °C was studied using the method of simultaneous thermal analysis. It was found that the interaction proceeds through two exothermic stages of 3.55 and 1.97 kJ/g. The thermal decomposition of the mixture consists of two stages - after the phase transition of potassium perchlorate in the first stage, its partial interaction occurs with the formation of calcium phosphide, which is then oxidized in the second stage at the melting point of potassium perchlorate. The composition of the resulting condensed products was studied using optical microscopy and X-ray phase analysis. It has been established that the process of interaction of a mixture of calcium hypophosphite with potassium perchlorate occurs in two stages, accompanied by the release of an aerosol of phosphoric acid and potassium chloride, and a condensed phase of calcium phosphates and potassium chloride is formed.
ТЕРМОГРАВИМЕТРИЧЕСКИЙ АНАЛИЗ ОБРАЗЦОВ КЕРНА СКВАЖИН ПОДЗЕМНОЙ ИССЛЕДОВАТЕЛЬСКОЙ ЛАБОРАТОРИИ
Authors: Е.Ю. Трояк , И.Н. Пожаркова , Т.А. Литвинская , Д.А. Озерский
Published: November 2024

Статья посвящена исследованию образцов керна скважин подземной исследовательской лаборатории, расположенных в Нижне-Канском скальном массиве Красноярского края. Целью работы являлась оценка изменения свойств горной породы при воздействии высоких температур на основе результатов термогравиметрического анализа образцов. В статье описана процедура отбора материала для проведения исследования и методика выполнения натурного эксперимента с использованием лабораторного оборудования. Обоснованы условия проведения опытов, включая длительность нагрева и создаваемый температурный режим. Описаны особенности испытуемых образцов, выявленные при визуальном осмотре. Представлены результаты измерения относительной потери массы образцов после их нагрева. Установлено, что при воздействии температур в диапазоне 300–800 °C наблюдается уменьшение массы образцов керна не более, чем на 1%, что свидетельствует об отсутствии значительных изменений свойств материала под влиянием процессов дегидрации и диссоциации в условиях испытаний. Данные, полученные в ходе исследования, могут быть использованы для обоснования безопасной эксплуатации подземной исследовательской лаборатории в аварийных ситуациях, связанных с пожарами.

The article is devoted to the study of core samples from wells of an underground research laboratory located in the Nizhne-Kansky rock massif of the Krasnoyarsk Territory. The purpose of the work was to assess changes in the properties of rock when exposed to high temperatures based on the results of thermogravimetric analysis of samples. The article describes the procedure for selecting material for research and the methodology for performing a full-scale experiment using laboratory equipment. The conditions for conducting the experiments are substantiated, including the duration of heating and the temperature regime created. The features of the test samples identified during visual inspection are described. The results of measuring the relative mass loss of samples after heating are presented. It has been established that when exposed to temperatures in the range of 300–800 °C, a decrease in the mass of core samples by no more than 1% is observed, which indicates the absence of a significant change in the properties of the material under the influence of the processes of dehydration and dissociation under test conditions. Data obtained during the study can be used to justify the safe operation of an underground research laboratory in emergency situations involving fires.
АНАЛИЗ ГИСТЕРЕЗИСНЫХ СВОЙСТВ МЕЛКОКРИСТАЛЛИЧЕСКИХ БЫСТРОЗАКАЛЕННЫХ СПЛАВОВ НА ОСНОВЕ РЕДКОЗЕМЕЛЬНЫХ МЕТАЛЛОВ
Authors: А.М. Ерёмин , Н.А. Манаков , В.А. Кыров
Published: November 2024

В данном исследовании проводится анализ процессов перемагничивания и характеристик гистерезиса в мелкокристаллических быстрозакаленных сплавах на основе редкоземельных элементов. Проведённое исследование структуры доменов и различных циклов гистерезиса указывает на то, что доменное смещение является основным механизмом перемагничивания в этих сплавах. На примере сплавов GdCo5было показано, что гистерезисные характеристики мелкокристаллических сплавов существенно отличаются от аналогичных свойств микрокристаллических материалов. Уникальные свойства гистерезиса, присущие мелкокристаллическим сплавам, могут служить экспериментальными критериями для определения ведущего механизма перемагничивания в высокоанизотропных дисперсных магнитах.

In this study, magnetization reversal processes and hysteresis characteristics in fine-crystalline rapidly quenched rare-earth alloys are analyzed. The conducted study of the domain structure and various hysteresis cycles indicates that the domain bias is the main mechanism of magnetization reversal in these alloys. Using the example of GdCo5alloys, it was shown that the hysteresis characteristics of fine-crystalline alloys differ significantly from similar properties of microcrystalline materials. The unique hysteresis properties inherent in fine-crystalline alloys can serve as experimental criteria for determining the leading mechanism of magnetization reversal in highly anisotropic dispersed magnets.
ЗАДАЧИ СО СВОБОДНЫМИ ГРАНИЦАМИ ДЛЯ ИЗОТЕРМИЧЕСКИХ ПОВЕРХНОСТЕЙ В МЕДИЦИНЕ
Authors: Ф.Х. Кудаева , И.В. Вешнева
Published: November 2024

Задачи со свободными границами для изотермических поверхностей играют важную роль в различных областях науки и техники. Их решение позволяет решать сложные физические проблемы, оптимизировать технологические процессы, развивать вычислительные методы и получать новые знания. Изотермические поверхности являются также определяющими при прогнозировании, управлении и оптимизации тепловых процессов, а не температурное поле. Для определения поля изотерм в данной работе получена задача на сопряжение со свободной поверхностью. Предлагается метод перехода задачи определения температурного поля к задаче определения изотермических поверхностей. Доказана монотонность оператора дифференцирования, что позволило сформулировать и доказать теорему единственности задачи Стефана для поля изотерм. Доказана теорема единственности решения задачи со свободными границами для изотермических поверхностей. Полученные результаты позволят исследовать взаимосвязи между физическими параметрами и биологическими эффектами. Результаты также найдут применение в криохирургии, криоконсервации, криотерапии, гипотермии.

Free boundary problems for isothermal surfaces play an important role in various fields of science and technology. Their solution allows solving complex physical problems, optimizing technological processes, developing computational methods and gaining new knowledge. Isothermal surfaces are also crucial in the prediction, management and optimization of thermal processes, rather than the temperature field. To determine the field of isotherms in this work, the problem of conjugation with a free surface is obtained. A method is proposed for the transition of the problem of determining the temperature field to the problem of determining isothermal surfaces. The monotony of the differentiation operator is proved, which made it possible to formulate and prove the uniqueness theorem of the Stefan problem for the field of isotherms. The uniqueness theorem of solving the problem with free boundaries for isothermal surfaces is proved. The results obtained will allow us to investigate the relationship between physical parameters and biological effects. The results will also be used in cryosurgery, cryopreservation, cryotherapy, hypothermia.
State and trends in the development of the microfinance market in Russia
Authors: Saifieva S. N. , Soklakova I. V. , Borshcheva A. V. , Ivanov M. D.
Published: November 2024

The relevance of the article is due to the insignificant contribution of microfinance to the development of the Russian economic system, especially in the context of supporting small and medium-sized businesses. However, the regulator sees it as a promising sector of the financial market and considers its progressive development necessary. The purpose of the work is to study the current state and identify trends in the development of the microfinance market in Russia. The methodological basis of the study includes empirical observation and analysis. During the work, official statistical data and scientific publications on the topic of microfinance have been used. The article provides a review of current legislative documents regulating the microfinance sector, and analyses the state of the market based on statistical data. It is substantiated that some elements of the monetary and financial policies pursued in the Russian Federation can be applied for the successful development of the microfinance sector, contribute to its effective and balanced work, and improve accessibility and sustainability. In the course of the work, key directions for the development of the microfinance market are formed: improving regulation and supervision; promoting financial literacy of the population; application of digital technologies; expansion and diversification of the product portfolio, development of partnerships, social entrepreneurship, which contribute to the sustainable development of this segment of the financial market. Particular attention is paid to a detailed analysis of improving the regulatory framework for microfinance in Russia from the point of view of legislation on bankruptcy of individuals, stimulating innovation and digitalisation, and supporting social entrepreneurship.
Seamless multimodality for passenger transportation in the Russian Federation
Authors: Stepanenko A. S. , Bolt A. S. , Bolt P. S.
Published: November 2024

The paper considers the formation of a seamless multimodal passenger transportation in order to develop transport infrastructure not only at the regional but also at the federal level. The positive aspects and disadvantages of a multimodal transport system are considered. The paper presents a review of the scientific literature on the above issues. The research methodology is based on proven approaches. Founded on the analysis of the tourist flow, it is proposed to build a system of seamless multimodal transportation in the territory of the Russian Federation (hereinafter referred to as RF). The relevance is due to the need to develop regional transport systems as well as consideration of this topic in the scientific literature, regulatory documents of the industry. Based on the Strategic direction in the field of digital transformation of the transport industry of the RF until 2030, the principles of multimodality are proposed to create a seamless system of multimodal passenger transportation. The development has been conducted for the transport system of the Altai Territory. Based on the data on tourist flows of the Federal State Statistics Service, the calculated route Moscow – Barnaul – Gorno-Altaysk is formed. The introduction of a digital platform for convenient search and booking of transportation is considered, the key points of working with requests are highlighted. The movement of financial and information flows and the algorithm of actions of the system participants are determined.
Interest of the Algerian diaspora for entrepreneurship in homeland: proposal of a model for its concretisation
Authors: Haddad A. , Lassoued R.
Published: November 2024

In the era of globalisation, diaspora is seen as a driving force for economic development in the countries of origin and for positive changes in the host countries. The Algerian diaspora represents a real opportunity and potential of entrepreneurs that are not exploited. This article attempts to explore the factors that encourage or hinder the entrepreneurial activities of the Algerian diaspora in its country of origin through a field survey based on 142 entrepreneurs from the studied diaspora. To do this, a logistic econometric modelling has been implemented to explain the entrepreneurial event (business creation), and the explanatory variables are the following factors: psychological (experience, training), contextual (discrimination, opportunities, and patriotism) sociological (help of relatives and other contacts) and economic (personal resources and those of the state). It appears that the probability of the project in Algeria is stronger as its leader from the Algerian diaspora has a great entrepreneurial potential and financial means, is an opportunist and patriot, benefits from the help of the state and knows how to activate, in case of difficulties, their personal contacts.
Financial management of an environmental enterprise
Authors: Kirova E. A. , Kurchenko A. A.
Published: November 2024

The article examines financial management of environmental enterprises from the standpoint of evaluating the results of financial analysis and specifics of its implementation. Increasing the competitiveness of environmental organisations in the Russian Federation and ensuring their prospects in the face of sanctions and restrictions at this stage of development is becoming increasingly relevant. The authors propose a methodology for financial analysis of industrial and environmental activities of an enterprise based on the calculation of key financial and private environmental indicators of environmental enterprises. The novelty of this study lies in an integrated approach to financial management based on the results of the analysis of financial and private environmental indicators of environmental organisations, covering the financial and environmental aspects of their activities. The integrated approach to financial management is innovative because it is founded on the close relationship between financial and environmental activities of enterprises. The presented article develops analytical support and methodological tools of the analysis for use by environmental enterprises, with consideration to their specifics, in order to improve the efficiency of financial management. The practical significance of this article lies in the analytical provision of effective financial management for the sustainable development of environmental enterprises.
Changing patterns of social services for the elderly as innovative technologies for preserving social capital
Authors: Sadykov R. M. , Bolshakova N. L.
Published: November 2024

The article examines the main problems faced by older people and suggests innovative practices and technologies of social care at home in order to preserve their social capital. Due to age and health conditions, many older people are limited in their ability to leave home and perform daily tasks and functions. Senile problems represent negative changes that affect people’s lives and are associated with poor health. The key problems of the elderly have been identified. The article notes that senior citizens need timely and long-term care to preserve their social capital, which is best provided at home and with the support of their loved ones. To implement such care, it is necessary to create long-term care centres for the elderly and the disabled. The authors of the article propose to develop services for the elderly at home, introduce innovative technologies and improve the quality of services provided. Social services play a special role in this, which is confirmed by the experience of public service centers. The introduction of innovative service practices and technologies, and the expansion of the number of social services are promising areas for preserving the social capital of the elderly.
Using the five-factor questionnaire to study the personality of a specialist-cynologist of the security agencies of the Russian Federation
Authors: Kusakina Е. А.
Published: November 2024

The article presents the results of using the Russian-language version of the “Big Five” personality questionnaire, in which personality is considered as a structure consisting of 5 factors, including many secondary factors. The subject of the study are psychological characteristics of the personality of dog handlers of law enforcement agencies of the Russian Federation (hereinafter referred to as RF) at various stages of professionalisation. The author emphasises the relevance of studying and further psychological support of the professional development of dog handlers, with consideration to the fact that specifics of their service and professional activities in order to ensure the security of the country have no analogues and are unique. The results of a focused interview with experienced dog handlers with extensive experience in service cynology have formed the basis for constructing a psychograph for a specialist in the profile in question. Using the “Big Five” methodology, it is possible to identify the characteristic features of cadets studying in the field of training “Animal Science”, profile “Cynology”, and employees of canine services of the law enforcement agencies of the RF. The author correlates the results obtained and notes the correspondence of the psychological qualities of both groups of respondents to the professionally oriented qualities presented in the psychograph of a specialist dog handler of the law enforcement agencies of the RF. The five-factor questionnaire adapted by A.B. Khromov adequately describes the psychological characteristics of an individual and can be used in the study of various aspects of its professional development.
Industry specialisation of the Kemerovsk region – Kuzbass: trends and problems that affect economic growth and development of the region
Authors: Bobko K. I. , Zatepyakin O. A. , Bobko T. V.
Published: November 2024

The article is devoted to studying the influence of industry specialisation of the Kemerovo region – Kuzbass on the economic growth of the entity. The purpose of the study is to identify the most significant trends and problems of the industry specialisation that affect the development of the region. Using methods of scientific knowledge – description, synthesis and generalisation of the data obtained; literature review, graphical method – the following has been conducted: analysis of the dynamics of structural changes in the gross regional product (hereinafter referred to as GRP) of the Kemerovo region – Kuzbass; assessment of trends in the movement of main industry indicators and indicators of regional industry. The information base of the study consists of foreign and domestic publications devoted to the analysis of the GRP sectoral structure; statistical data from the Federal State Statistics Service and its territorial authority for the Kemerovo Region – Kuzbass. Based on the analysis of the structural changes dynamics, an increase in the contribution of the raw materials sector to the country’s gross domestic product and an increase in the share of mineral extraction in the industry structure of the GRP of the Kemerovo region – Kuzbass have been revealed. The trend of decrease in the industrial production index is analysed, it is shown that it has a trend similar to the dynamics of the decline in mining production, and the reasons for the decline are described. The strengthening trend of economic growth in the Kemerovo region – Kuzbass based on the raw model has been determined. East Asian models of economic growth are considered. The expediency of using international experience in the design of high-tech industries on the basis of private investment in the research and development sector, and its adaptation to the realities of the development of Russian regions is indicated. A conclusion is drawn about the need to support the technological sovereignty of the country and the transition of the development of the Kemerovo region – Kuzbass to a non-primary model.
Event tourism in Azerbaijan: current state and mechanisms for its improvement in the context of world experience
Authors: Akhundova A. G.
Published: November 2024

Event tourism is a dynamically developing sector of the global tourism industry, the share of which increases by 1.5% annually. This segment plays a key role in stimulating the local economy, attracting investment and developing cultural exchange. In Azerbaijan, which has a rich historical and cultural heritage, event tourism has significant potential. However, its development in the regions faces a number of problems that need to be addressed for more efficient use of existing opportunities. This article discusses the current state of event tourism in Azerbaijan, studies certain events held in the republic, substantiates its importance for the socio-economic development of the country’s regions and proposes mechanisms for its improvement based on international experience. The purpose of this article is to analyse the current state of event tourism in Azerbaijan, assess its potential for the socio-economic development of regions and develop recommendations for its improvement, considering existing problems and prospects. The object of the study is to identify problems and explore opportunities related to the development of event tourism in Azerbaijan. The subject of the research is the mechanisms for improving event tourism in the regions of Azerbaijan, including the analysis of current problems, assessment of potential and development of recommendations for improving the accompanying infrastructure, financing, marketing and other key aspects in the context of studying and applying foreign experience. The work uses an analytical research method based on a review of scientific papers in the field of event tourism.
Analysis of modern air transportation in Russia
Authors: Petrova T. A. , Kardanov V. A.
Published: November 2024

Modern air cargo transport is an important part of global logistics and trade. They provide fast and efficient delivery of goods all over the world. In recent years, there have been several significant changes in the development of air routes both in the Eurasian Economic Union (hereinafter referred to as EAEU), and in Russia, in particular. Additionally, in light of recent global events such as the COVID-19 pandemic, air cargo has faced additional challenges related to restrictions on passenger flights, changes in airport operating hours and increased health regulations, while the geopolitical situation has had a significant impact on transport and development of transport infrastructure throughout the EAEU. All these challenges make this study relevant. In addition, the article examines the rules of law that regulate issues of economic and customs space, as well as solve the problems of applying bans on customs duties and other restrictions on the free movement of goods, services and financial resources. Ways have been proposed to overcome restrictions on air transportation within the framework of the EAEU.
Transformation of the currency regulation regime and foreign economic relations of Russia in the context of expanding anti-Russian sanctions
Authors: Anikin O. B. , Fedin O. M.
Published: November 2024

The article discusses the features of currency regulation and foreign economic relations of the Russian Federation (hereinafter referred to as RF, Russia) in the context of the introduction and growth of anti-Russian sanctions by the United States of America, European Union countries and other unfriendly countries, issues related to ensuring the sustainability of the Russian economy and its ability to withstand negative internal and external influences, issues of financial security, which is an important component of the country’s economic security, issues of the current state of the state’s banking system and the Russian economy as a whole. The article also discusses the possible expansion of international economic relations between Russia, China, North Korea and other countries. The purpose of the article is to identify directions for the transformation of the currency regulation regime and foreign economic relations of the RF in the context of the expansion of anti-Russian sanctions. The subject of the study is the currency and foreign economic relations of the RF with friendly and unfriendly countries in the current conditions of growing anti-Russian sanctions and the conduct of a special military operation in Ukraine. In conclusion, the article highlights key changes associated with changes in Russia’s foreign exchange and foreign economic activeities, promising opportunities for further expansion of international economic relations with China, the Democratic People’s Republic of Korea and other friendly countries.
Labour productivity, its main indicators, forms of manifestation, and ways to improve
Authors: Matskulyak I. D.
Published: November 2024

The purposes of the article are to study the content of labour productivity, generalise its main indicators, essence of constant trends manifested in the form of an economic law, disclose its forms of manifestation and ways to increase as well as to attract the attention of subjects of these processes to take regulatory measures. The object of the study is labour in the main link of the economy. The subject are political and economic, social and labour relations between participants of the production process regarding the increase in the labour productivity. Its methodological framework covers provisions explaining the nature of the continuity of labour processes based on the labour productivity. Its main sources are considered using the methods of scientific abstraction, comparison, logical, historical, causal, dialectical methods. Among the scientific results is the conclusion about the essence of the economic law of increasing productivity of social labour, about some properties of the forms of its manifestation, number of directions for accelerating the increase and continuity of the labour process. The scientific and practical significance of the article lies in the possible usefulness for the main link of the economy which corrects its own strategies and development programmes of authorities at various levels during the implementation of economic policy as well as of higher educational institutions of the country where economic theory and labour economics are taught.
Personal income in New Zealand at the current stage of economic development
Authors: Mitroshin I. V.
Published: November 2024

Any socio-economic processes occurring in the country and world have an impact on the standard of living of the population. There are many indicators that determine the standard of living of citizens, among which we can highlight the income of people as the main component of their financial well-being. In a period of global political and economic upheavals, the relevance of the topic of human quality of life is beyond doubt. During the economic war organised by the West against Russia, the countries participating in this war are of interest. These include New Zealand, although it is clear that due to the distance from Russia and weak economic ties between the countries, there will be no significant mutual influence of the sanctions restrictions. The study has analysed the income of the population of New Zealand over the past 10 to 15 years, considering differentiation by various categories, such as geographical location, qualification, and source of income. The analysis has showed a certain increase in the income and, accordingly, in the standard of living of the country’s population in the period under review. An insignificant impact on this indicator of restrictive measures during the COVID-19 pandemic is revealed, however, with the certain social policy of the state, fluctuations in the income of citizens during this period were hardly noticeable. Their assessment by sources has reflected the significant share of small businesses in the country’s economy, which shows a high degree of liberalisation of the national economy of the state. The analysis of the citizens’ incomes by geographic regions has revealed a significant impact of urbanisation on the standard of living of the New Zealand’s population, which is a global trend.
review on vital role of regulatory affairs in pharmaceutical industry
Authors: Basak Piyali , Das Rajarshi , Mallick Sonia , Ray Jaydip
Published: November 2024

The burgeoning field of Regulatory Affairs (RA) serves as the foundation for ensuring public health in today's globalized marketplace. In the pharmaceutical industry, regulatory affairs play a crucial role in assuring the safety, efficacy, and quality of drug products, which are essential for the approval of new products entering the market. Emerging from a collective international desire to protect individuals from potentially harmful medications, this profession bridges the gap between pharmaceutical companies and regulatory agencies, ensuring that products meet all necessary legal and scientific standards.Regulatory affairs professionals act as guardians, meticulously ensuring the accuracy and completeness of product information. They navigate the complex labyrinth of regulations, translating them into practical plans for companies to follow. Their expertise encompasses the entire life cycle of a drug, from initial application submission and oversight of clinical trials to ongoing adherence to evolving regulatory requirements. This comprehensive approach guarantees the development, manufacturing, and distribution of safe and effective medications across various fields, including traditional pharmaceuticals, veterinary medicine, medical devices, and complementary therapies.As the pharmaceutical landscape continues to evolve, the demand for highly skilled regulatory affairs professionals remains strong. In India, the Central Drug Standard Control Organization (CDSCO) regulates drug legislation, facilitating drug development from initial research to market approval and post-marketing surveillance.
Natriuretic Peptides- An Overview
Authors: R Vijendra , H P Pundarikaksha , K Girish
Published: November 2024

Natriuretic peptides which are endogenous substances play a key role in the renal and cardiovascular homeostasis and are also involved in various pathophysiological processes. Recombinant natriuretic peptides as well as inhibitors of enzymes modulating the effects of natriuretic peptides have potential diagnostic and therapeutic applications in many clinical conditions
Continuing Medical Education Program
Authors: S. Shankar P.
Published: November 2024

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Primary Malignant Melanoma of the oral cavity: A Case Report
Authors: PJ Yaranal , K Shreesha , N Umaru
Published: November 2024

Primary malignant melanoma of oral mucosa is a rare disease. The common sites of its occurrence are the palate and gingiva with the maxillary arch being affected 80 of the time. Because of their presence at relatively obscure areas in the oral cavity most of the malignant melanomas of the oral cavity are diagnosed at a late stage. These lesions are associated with poor prognosis. Therefore the clinicians must carefully examine the head neck and oral cavity for pigmented lesions and biopsied to rule out malignancy. We present a case of malignant melanoma of the oral cavity and briefly review the relevant literature that explains the nature of this lesion.nbsp
Localised Cutaneous Leishmaniasis in non Endemic area
Authors: S Permi Harish , Chandan Rajesh , H Makannavar J , Prasad Kishan
Published: November 2024

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Giant Congenital Melanocytic Nevus of Scalp, mimicking Turban Tumor
Authors: Shetty Jayaprakash , P Bhat Shubha , BK Sathishchandra , Shetty Vikram
Published: November 2024

Giant congenital melanocytic nevi are rare and occur in about one out of every 2 lakh to 5 lakh births. The common site is the lower back and thigh where it is distributed in a garment fashion and is termed as bathing trunk nevus. When it occurs on the scalp it presents as thickened folds of skin with deep furrows and convolutions. This descriptive term is called Cutis verticis gyrate CVG which clinically resembles cylindroma Turban tumor. We are reporting a case of a 16 year old girl with Giant congenital melanocytic nevus of scalp. The case is being presented because of its rarity.nbsp
Giant Rhinolith: A rare clinical entity of the Nasal Cavity
Authors: M Naik Sudhir , S. Naik Sarika
Published: November 2024

Rhinolith is a calcified concretion of a nidus within the nasal cavity. Giant rhinoliths are now a very rare occurrence since improved diagnostic techniques such as endonasal endoscopy makes a faster diagnosis. Endonasal endoscopic removal of the Rhinolith measuring 3x3 cm was done under general anaesthesia. Smaller rhinolithscan be removed easily under local anaesthesia amp larger rhinoliths can be removed using endonasal endoscope under general anesthesia.nbspnbsp
Predispopsing factors and clinical study of otomycosis in the Southern sub tropical regions of India
Authors: Vinay Vaidyanathan , Kishore Chandra Shetty , Sreenath Kamath , Ratan Shetty
Published: November 2024

Need for the study Otomycosis is a fungal infection of the external ear middle ear and open mastoid cavity. Fungal infections are more frequently encountered in tropical and sub-tropical climates or during periods of intense heat and humidity. Mangalore is a costal city which is situated in the southern Dakshin Kannada district of India. Because of the moist and humid climate it witnesses large number of cases of fungal infections. Hence its a good setting to study the predisposing factors and clinical presentation of fungal infections of ear. Materials and methods Data was collected from 126 patients attending otorhinolaryngology out patient department ENT OPD at K S Hegde Medical Academy Mangalore Karnataka. It is a Descriptive Study where hundred and twenty six patients of all age groups and both sexes were enrolled with Purposive Sampling Technique. Results Many predisposing factors were attributed of which use of unsterile sticks and swabs 72 and use of unsterile oil and oil mixture 69 were common. The patients presented with common complaints of itching 92 and pain 85 and less frequently with tinnitus and ear discharge more so in rainy season. Canal hyperemia and oedema were common examination findings. The mycological appearance was that of wet brownish black or gray mouldy matsspores with epithelial debris and wet blotting paper when associated with candida species in majority of the patients. Lack of cerumin and unhealthy wax were the common physical signs. Conclusion No age group or sex is immune to otomycosis. Manipulated external auditory canal is predisposed to infection. Common clinical presentation being of otitis externa of variable severity. Inflammatory changes with myocological appearance of wet brownish black gray mouldy mats spores with epithelial debris with lack of cerumin being the common appearance
Serum Lipase as an Indicator for Predictability of Surgical Complications in Acute Pancreatitis
Authors: V Satish , . Bhagavan.BC , . Sridhar , . Vishnu.V
Published: November 2024

Acute pancreatitis is a common acute abdominal condition affecting the physically active age group leading to considerable financial problems. Alcohol is the most significant etiological agent. Biochemical tests can diagnose the condition accurately and radiological assessment can guide in the severity of the disease. Significant improvement in the Ransons score 2 indicates that conservative management is the treatment of choice. Most of the complications require only conservative management. Serum lipase is significant indicator for the development of peripanceatic collections and necrosis. Increasing levels of serum amylase is a significant indicator of pancreatic pseudocyst developmentnbsp
Primary Non-Hodgkin's Lymphoma of the Thyroid with Lymphocytic Thyroiditis
Authors: V Satish , BC Bhagavan , . Sridhar.
Published: November 2024

Primary lymphoma of thyroid is one of the very rare entities accounting to less than 2 of thyroid malignancies. We present a case of primary Non-Hodgkins Lymphoma of thyroid with Lymphocytic thyroiditis in a 55 year old woman. The patient presented with a rapidly growing diffuse nodular mass in the thyroid. The histological features were consistent with large cell Non- Hodgkins Lymphoma of the thyroid with associated thyroiditis.
New Approaches in the Treatment of Bronchial Asthma
Authors: P. S Shankar
Published: November 2024

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PLACEBO-Uses and Criticisms
Authors: Krishnamurthy K.
Published: November 2024

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Regenerative Medicine with Stem Cells
Authors: Shankar P.S.
Published: November 2024

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Spondyloepiphyseal Dysplasia Tarda with Progressive Arthropathy': In 3 siblings with unusual Association
Authors: M Kulkarni Akhil , L Kulkarni Muralidhar , Kumar Sukhani Vijay , V Kulkarni Suhasini , KK Sanjana , Giriyappa Chandan
Published: November 2024

We report a case series of Spondyloepiphyseal dysplasia tarda with progressive arthropathy SEDT-PA in three siblings. SPEDT-PAis a rare autosomal recessive skeletal dysplasia affecting primarily the articular cartilage with characteristic skeletal abnormalities notably in the spine. First reported by Wynne-Davies et al. who estimated its prevalence to be about 3.4 per million population and an incidence of 1 per 100000 1. live births Because of its striking resemblance to juvenile rheumatoid arthritis it has various synonyms like progressive pseudorheumatoid 2. arthropathy of childhood PPAC and progressive pseudorheumatoid dysplasia PPDA MIM No. 208230 In the present context we present three affected siblings of an inbred south Indian Hindu family with one of them having an unique association of Pierre Robin sequence PRS.
Mobile Phone dependence among College Students in Bangalore
Authors: R Ramesh Masthi N , . Yashasvini
Published: November 2024

Mobile phones of late are being linked to certain diseases. Amore serious issue is the problem of dependence among mobile phone users.Objective To assess the prevalence of mobile addiction among the study subjects and to assess the clinical and behavioral manifestations. Subjects and methods The study was conducted in the Bangalore city covering about 11 Colleges from March 2008 ndash July 2008. The study subjects included pre-university degree post graduate engineering dental and medical colleges students. It was a cross-sectional exploratory study.Results The prevalence of mobile phone addiction in our study was 3.2.The commonest behavioral changes observed were feeling lonely irritated insecure and incomplete. The commonest clinical manifestations observed were headache ear pain neck pain and thumb pain.nbsp
Double Neural Tube Defect
Authors: ML Kulkarni , S Nirupama , K Gayathri , Raghoji Chaitali , . Jayalakshmi , Ahmed Ifthiqhar , Shazia Salma
Published: November 2024

Double neural tube defect is a rare congenital malformation and as the name suggests is characterized by abnormal closure in two different regions of the neural tube along the course of development of the human nervous system. Acase illustration and current literature on multisite closure of neural tube is discussed. The case of a term baby girl with frontal encephalocele and thoracolumbar meningomyelocele is reported
Sotos Syndrome
Authors: L.Kulkarni Muralidhar , M.Kulkarni Akhil , SS Sidramayya , VV Vivekanand
Published: November 2024

Sotos Syndrome is an overgrowth syndrome characterized by three major features namely distinctive facial gestalt macrocephaly and variable degree of learning difficulties. It is one of the most common overgrowth conditions but the exact estimated birth incidence is unknown. Mutations and deletions of NSD1 a histone methyl transferase implicated in transcriptional regulation is responsible in most of the cases.
Oro- Facial Sarcoidosis- An Unusual Primary Presentation
Authors: CN Yogishwarappa , GP Prafulla
Published: November 2024

Three cases of diffuse lip swelling presented for the cosmetic and functional reason. In two cases there was associated gum and cheek swelling.. In all three cases biopsy showed histological evidence of non-caseating epithelioid granulomas and coalescing aggregates of epithelioid histiocytelymphoid cells.Small dose of intralesional steroid resulted in near complete regression with no recurrence with 1 year follow-up