bluuebunny/crossref_metadata_2025 huggingface dataset:
Küstenschutzmaßnahmen in Togo — Stabilisierung erosionsgefährdeter Strandabschnitte und Schutz des Containerterminals Lomé durch den Neubau einer Buhne
Authors: Spekker Heiko , Ammermann Klaus , Guillart Delphine , Lankenau David
Published: June 2010

Die Küste Togos am Golf von Guinea in Westafrika verfügt über keinen natürlichen Schutz, z. B. durch vorgelagerte Inseln oder felsige Uferabschnitte. Der gesamte rd. 65 km lange Küstenstreifen besteht aus Sand und ist daher dem Wellenangriff des Atlantiks und der überwiegend vorhandenen West‐Ost‐Strömung ausgesetzt. Da die Uferbereiche traditionell dicht bewohnt sind, stellen Landverluste durch Erosion ein großes Problem für die Bevölkerung und die Infrastruktur dar. Die Erosionsproblematik wird daher von der togoischen Regierung sehr intensiv verfolgt. Von den rd. 6 bis 7 Millionen Togoern leben rd. 2,5 Millionen im Großraum Lomé direkt an der Küste. Durch den Bau zusätzlicher und die Rehabilitierung vorhandener Buhnen sollen langfristig der Küs tenabschnitt Togos stabilisiert und die Schutzziele erreicht werden. Die technische Umsetzung der von der INROS LACKNER AG geplanten und zu überwachenden Küstenschutzmaßnahmen wird detailliert beschrieben.

Coastal protection measures in Togo — stabilization of erosionthreatened sections of the beach and protection of the container terminal Lomé by means of a sea groyne. The coast of Togo at the Gulf of Guinea, situated in West Africa is not sheltered by natural protection, such as offshore islands or rocky shorelines. The approximately 65 km long Atlantic Ocean coastline does mainly consist of sand, which is prone to erosion due to wave attacks and the prevailing west‐east current. With a traditionally dense populated coast, the land losses caused by erosion constitute a main issue for the Togolese as well as for the infrastructure in general. The problems caused by erosion are therefore vigorously pursued by the Togolese Government. Greater Lomé, located at the coast, accommodates 2,5 Million of the 6 to 7 Million Togolese people. The construction of additional and maintaining of existing groins would stabilize Togo’s coastline. The article describes the technical implementation of coastal protection measures designed and supervised by INROS LACKNER AG.
An LC‐MS‐MS method for quantitative determination of maraviroc (UK‐427,857) in human plasma, urine and cerebrospinal fluid
Authors: Brewer Ed , Felix Tonya , Clarke Phil , Edgington Alan , Muirhead David
Published: June 2010

Maraviroc is a first‐in‐class CCR5 antagonist that shows potent anti‐HIV‐1 activity in vitro and in vivo and is well tolerated in both healthy volunteers and HIV‐1‐infected patients. The method for determination of maraviroc (UK‐427,857) and its major metabolite (UK‐408,027) in human plasma consists of a protein‐precipitation procedure and analysis by liquid chromatography/tandem mass spectrometry using positive ion TurboIonSpray® ionization and multiple reaction monitoring. The assay has been validated over a concentration range of 0.500–500 ng/mL for both analytes. The determinations of maraviroc in human cerebrospinal fluid (0.500–500 ng/mL) and in urine (5.00–5000 ng/mL) have also been validated but do not include measurement of the metabolite. The validations included extraction recovery, intra‐assay and inter‐assay precision and accuracy, stability of stock and spiking solutions, freeze–thaw stability, matrix stability, processed‐extract stability, and evaluation of potential interferences from selected medications in plasma or urine. Copyright © 2010 John Wiley & Sons, Ltd.
The morphology of the human lymphatic vessels in the head and neck
Authors: Pan Wei‐Ren , le Roux Cara Michelle , Levy Sidney M. , Briggs Christopher A.
Published: June 2010

Previously little has been written about the morphology of the human lymphatic vessels since Sappey (Sappey [1874] Anatomie, Physiologie, Pathologie des Vaisseaux Lymphatiques, Paris: Adrien Delahaye) over 100 years ago. There needs to be an accurate re‐evaluation of scientific observations to aid clinical management. Forty‐nine combinations of tissue from the head and neck of 20 unembalmed human cadavers were studied. Six percent hydrogen peroxide was used to find the vessels. They were injected with radio‐opaque mixture, dissected, photographed, and radiographed. Final results were transferred to the computer for analysis. Different sized lymphatic valves were found in the precollecting and collecting lymph vessels, the lymphatic trunks, and ducts. The intervals between the valves were of various lengths. Diverse lymphatic ampullae and diverticula were seen in precollecting and collecting lymph vessels. Initial lymph vessels arose from the dermis, the galea, and the mucosal membrane. The vasculature of the direct and indirect precollecting and collecting lymph vessels, lymphatic trunks, and ducts was recorded. The morphology of the human lymphatic vessels in the head and neck has been described and recorded using radiographs and photographs. Clin. Anat. 23:654–661, 2010. © 2010 Wiley‐Liss, Inc.
Live‐Cell Imaging with Water‐Soluble Aminophenoxazinone Dyes Synthesised through Laccase Biocatalysis
Authors: Bruyneel Frédéric , D'Auria Ludovic , Payen Olivier , Courtoy Pierre. J. , Marchand‐Brynaert Jacqueline
Published: June 2010

Aminophenoxazinone dyes with variable water solubilities were assayed for the first time in a live‐cell imaging application. Among a library of ten sulfonylated chromophores, one compound gave excellent results as an endocytic marker, showing a precise subcellular distribution. The compound was compared to four commercial vital tracers, including Lucifer Yellow. The first laccase‐mediated regioselective synthesis of a diphosphorylated 2‐aminophenoxazinone dye was also described. This compound, water‐soluble at 10−2 M, displayed modest fluorescence properties and the ability to complex Mg2+ and Ca2+ cations, therefore giving fluorescence quenching.
Catastrophe and homeostasis
Authors: Silman Robert
Published: June 2010

The seasonal change in the duration of the night time release of melatonin is responsible for activating the hypothalamic gonadtrophin‐releasing hormone (GnRH) pulse generator in seasonal breeding animals. Paul Mullen and I considered that it might also be responsible for the activation of the child's GnRH pulse generator at the onset of human puberty. The real conundrum, though, is why this should happen when it does. Homeostasis, which explains how the body is able to maintain itself, cannot explain why things change. Our reasoning was that in any homeostatic state, there might exist two systems in disequilibrium, which eventually collide to create the ‘catastrophe’ of change. Our research showed that a constant daily output of melatonin throughout life was in disequilibrium with increasing body mass throughout childhood. These two systems permit the progressive decrease in the circulating concentration of melatonin in the growing child until it drops below a critical threshold, which then creates the ‘catastrophe’ of puberty. Catastrophe is destined to overthrow the established order, whereas homeostasis protects it. Catastrophe is always a transient moment that is rapidly supplanted by the re‐imposition of homeostasis. Copyright © 2010 John Wiley & Sons, Ltd.
The evolution of forensic mental health services in Victoria, Australia: Contributions of Professor Paul Mullen
Authors: Ogloff James R. P.
Published: June 2010

Background This paper provides an overview of the development of forensic mental health services in Victoria, Australia, from the time that Paul Mullen was appointed Foundation Professor of Forensic Psychiatry at Monash University in 1992 until his retirement in 2009.

Aim To provide a brief overview of the inpatient and outpatient service development within the Victorian Institute of Forensic Mental Health (Forensicare) as well as some of the research contributions he has made that have contributed to the development of novel specialised services including the Problem Behaviour Programme.

Conclusions Although applied to the Victorian Institute of Forensic Mental Health, the factors that emerged as a result of his leadership serve as guidelines for the development of prestigious forensic mental health services anywhere. Copyright © 2010 John Wiley & Sons, Ltd.
Mechanism of Laccase–TEMPO‐Catalyzed Oxidation of Benzyl Alcohol
Authors: Tromp Sander A. , Matijošytė Inga , Sheldon Roger A. , Arends Isabel W. C. E. , Mul Guido , Kreutzer Michiel T. , Moulijn Jacob A. , de Vries Simon
Published: June 2010

The oxidation of benzyl alcohol by air, catalyzed by the organocatalyst TEMPO and the enzyme laccase has been investigated. To establish the kinetically significant pathways and corresponding kinetic parameters, a series of experiments is conducted with synthesized stable oxidized and reduced forms of the organocatalyst, the oxoammonium cation, and hydroxylamine. The time course of TEMPO and its oxidized and reduced derivatives is monitored off line by a combination of GC analysis, UV/Vis spectroscopy, EPR spectroscopy, and FTIR spectroscopy. TEMPO is found to be regenerated through noncatalyzed comproportionation of the oxoammonium cation with hydroxylamine. A kinetic model is presented based on the experimentally determined kinetically significant pathways. The time dependences of the concentrations of the three redox states of TEMPO and benzyl alcohol are adequately described by the model. The results provide new leads for the development of a practical process for a combined laccase–TEMPO‐catalyzed selective oxidation of alcohols.
ChemInform Abstract: Anhydrous Sulfates of Rare Earth Elements: Syntheses and Crystal Structures of Y2(SO4)3 and Sc2(SO4)3.
Authors: Wickleder Mathias S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (NH4)15 [H3Mo57V6(NO)6 O189(H2O)12(VO)6] ×≈60H2O: New Nanocompound Obtained by Chemical Embellishment of {M57V6}.
Authors: Yang Wenbin , Lin Xiang , Lu Canzhong , Zhuang Honghui , Huang Jinshun
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient and Efficient Procedure for Selective Deprotection of Acetates by Titanium(IV) Isopropoxide.
Authors: Ranu Brindaban C. , Guchhait Sankar K. , Saha Manika
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,3‐Bis(phenylmercapto)propane and 1‐Chloro‐3‐(phenylmercapto)propane: Useful Precursors for 1,3‐Dilithiopropane Synthons in the Preparation of 1,5‐Diols.
Authors: Foubelo Francisco , Yus Miguel
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Suzuki‐Type Cross‐Coupling Reaction of Cyclopropylboronic Esters with Benzyl Bromides.
Authors: Chen Han , Deng Min‐Zhi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium‐Catalyzed Stereospecific Ring Expansion Reaction of Allenylcyclobutanols with Aryl Iodides: A Novel Route to the α‐Substituted Cyclopentanones with Quaternary Carbon Stereocenters.
Authors: Yoshida Masahiro , Sugimoto Kenji , Ihara Masataka
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transformations of 6‐Methylsulfonylbicyclo[3.1.1]heptanes in the Presence of Potassium Hydroxide in tBuOH—CCl4 Medium.
Authors: Vasin V. A. , Romanova E. V. , Kostryukov S. G. , Razin V. V.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Rearrangement Route to Fenvaleric Acid.
Authors: Luzzio Frederick A. , Fitch Richard W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of (2R,3S)‐3‐(N,N‐Dibenzylamino)‐1‐thiophenylbutan‐2‐ol.
Authors: Sengupta Saumitra , Sarma Debarati Sen
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies in a Tetrafluorotricyclo[5.2.1.02,6]decane Series.
Authors: Nowak Ireneusz
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design, Synthesis, and Structure—Activity Relationships of Novel Non‐Imidazole Histamine H3 Receptor Antagonists.
Authors: Linney Ian D. , Buck Ildiko M. , Harper Elaine A. , Barret‐Kalindjian S. , Pether Michael J. , Shankley Nigel P. , Watt Gillian F. , Wright Paul T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polycations. Part 7. Polycationic Cyclic Alkynes.
Authors: Cohen JaimeLee Iolani , Engel Robert
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Towards Diversity‐Oriented Stereoselective Syntheses of Biaryl‐ or Bis(aryl)metal‐Containing Medium Rings.
Authors: Spring David R. , Krishnan Shyam , Schreiber Stuart L.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Applications of (R)‐ and (S)‐7,7′‐Dimethoxy‐2,2′‐bis(diphenylphosphino)‐1,1′‐binaphthalene.
Authors: Che Daqing , Andersen Neil G. , Lau Stephen Y. W. , Parvez Masood , Keay Brian A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Optically Active Sugar Thioamides from δ‐Gluconolactone.
Authors: Arevalo Maria J. , Avalos Martin , Babiano Reyes , Cabanillas Andres , Cintas Pedro , Jimenez Jose L. , Palacios Juan C.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Thin Films in Recording Technology
Authors: Speriosu V. S. , Herman, D. A. Jr. , Sanders I. L. , Yogi T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Monoorganopalladium Complexes Relevant to Catalysis
Authors: Yamamoto Akio , Kayaki Yoshihito , Nagayama Kazuhiro , Simizu Isao
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Special Issue on Human Resource Management and the SME: Toward a New Synthesis
Authors: Katz Jerome A. , Aldrich Howard E. , Welbourne Theresa M. , Williams Pamela M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Eigenvalues as Molecular Descriptors
Authors: Randic Milan , Vracko Marjan , Novic Marjana
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Personal View About Topological Indices for QSAR/QSPR
Authors: Balaban Alexandru T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Th4(PO4)4P2O7, an Original Ultralow Expansion Material.
Authors: Launay S. , Wallez G. , Quarton M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Vibrational Properties of Monophosphate Tungsten Bronzes (PO2)4(WO3)2m (m = 4, 6).
Authors: Zhu Z.‐T. , Musfeldt J. L. , Teweldemedhin Z. S. , Greenblatt M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: SmI2‐Mediated Allylation of Aldimines with Allyl Bromide.
Authors: Kim Byeong Hyo , Han Rongbi , Park Ryun Ju , Bai Kyung Ho , Jun Young Moo , Baik Woonphil
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ferric Chloride Induced Catalytic Cleavage of Oximes and Hydrazones under Solvent‐Free Conditions.
Authors: Bose D. Subhas , Narsaiah V. Venkat , Goud P. Ravinder
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: CuI‐Catalyzed Coupling Reaction of β‐Amino Acids or Esters with Aryl Halides at Temperature Lower Than That Employed in the Normal Ullmann Reaction. Facile Synthesis of SB‐214857.
Authors: Ma Dawei , Xia Chengfeng
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: ω‐Pentafluoro‐λ6‐sulfanyl (SF5)‐n‐perfluoroalkyl Benzene Derivatives.
Authors: Hodges Anna Marie , Winter Rolf , Mohtasham Javid , Bailey Pauline , Gard Gary L.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polyphenylene Dendrimers with Different Fluorescent Chromophores Asymmetrically Distributed at the Periphery.
Authors: Weil Tanja , Wiesler Uwe M. , Herrmann Andreas , Bauer Roland , Hofkens Johan , De Schryver Frans C. , Muellen Klaus
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Self‐Assembly of Folded m‐Phenylene Ethynylene Oligomers into Helical Columns.
Authors: Brunsveld Luc , Meijer E. W. , Prince Ryan B. , Moore Jeffrey S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Copper‐Catalyzed Coupling Reaction of Terminal Alkynes with Aryl‐ and Alkenyliodonium Salts.
Authors: Kang Suk‐Ku , Yoon Seok‐Keun , Kim Young‐Mook
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heterocycles in Organic Materials Chemistry. Synthesis of Di‐, Tri‐, and Tetraimide Polycarboxylic Acids (I) for Use in Organic Network Assembly.
Authors: Feldman Ken S. , Liu Yanze , Saunders Joe C. , Masters Katherine M. , Campbell Robert F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel [60]Fullerene Amino Acid for Use in Solid‐Phase Peptide Synthesis.
Authors: Pellarini Federica , Pantarotto Davide , Da Ros Tatiana , Giangaspero Anna , Tossi Alessandro , Prato Maurizio
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of C2‐Symmetric Bisthiazolidine Ligands Derived from L‐Cysteine.
Authors: Diaz Sandra , Gonzalez Asensio
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparative Synthesis of 3‐Cyano‐4‐difluoromethyl‐ and 3‐Cyano‐4‐trifluoromethyl‐2(1H)‐pyridones.
Authors: Pashkevich K. I. , Sevenard D. V. , Khomutov O. G. , Vorontsov I. I.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Equivalent of α‐Nitroformylacetic Acid.
Authors: Nishiwaki Nagatoshi , Ohtomo Hiromi , Tamura Mina , Hori Kazushige , Tohda Yasuo , Ariga Masahiro
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthesis of 4‐Phenylquinolines by Reaction of 2‐(α‐Bromobenzyl)oxiranes with Aniline Derivatives.
Authors: Karikomi Michinori , Tsukada Hiroshi , Toda Takashi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Modified von Niementowski Synthesis of Novel Derivatives of 5a,14b,15‐Triazabenzo[a]indeno[1,2‐c]anthracen‐5‐one from Indolo[1,2‐c]quinazoline.
Authors: Domon Lisianne , Le Coeur Catherine , Grelard Axelle , Thiery Valerie , Besson Thierry
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Complexation of a Novel Soluble vic‐Dioxime Ligand.
Authors: Guersoy Sueleyman , Cihan Ali , Kocak Makbule B. , Bekaroglu Oezer
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tetrakispyridinium Derivative of Perfluorosuccinic Acid Dimer.
Authors: Odinokov V. N. , Akhmetova V. R. , Savchenko R. G. , Bazunova M. V. , Khalilov L. M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Liquid Membrane Transport Properties of Photolabile Molecular Clips (I) Based on Dithiane‐spiro‐crown Ethers.
Authors: Barnhurst Loren A. , Kutateladze Andrei G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intramolecular Electrophilic Rearrangements in Saturated Acyclic Systems. Reactivity of the Zwitterion Derived from Triisopropylphosphine and Ethyl 2‐Cyanoacrylate with Respect to Different Types of Electrophiles.
Authors: Gololobov Yu. G. , Galkina M. A. , Dovgan O. V. , Krasnova I. Yu. , Petrovskii P. V. , Antipin M. Yu. , Voronzov I. I. , Lyssenko K. A. , Schmutzler R.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hydrophosphinoyl Derivatives of Calix[4]resorcinarenes
Authors: Nikolaeva I. L. , Burilov A. R. , Pudovik M. A. , Habicher W. D. , Konovalov A. I.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,4‐Migration of Et3Ge Group in 1‐Triethylgermoxypropyne.
Authors: Novokshonov V. V. , Medvedeva A. S. , Mareev A. V.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Paeonilactone‐A Adducts Formed by Anaerobic Incubation of Paeoniflorin with Lactobacillus brevis in the Presence of Arylthiols.
Authors: Abdel‐Hafez Atef A. , Meselhy Meselhy R. , Nakamura Norio , Hattori Masao , El‐Gendy Mahmoud A. , Mahfouz Nadia M. , Mohamed Tarek A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereomeric Diterpenes from Coleus blumei.
Authors: Ragasa Consolacion Y. , Templora Vilma F. , Rideout John A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Mesomorphic Properties of Cholesteryl p‐Polyfluoroalkoxy‐m‐nitrobenzoate.
Authors: Wang Kan , Li Hengfeng , Wen Jianxun
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Steroidal Glycosides Bearing the Disaccharide Moiety of OSW‐1 and Their Antitumor Activities.
Authors: Ma Xingquan , Yu Biao , Hui Yongzheng , Miao Zehong , Ding Jian
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sulfated Steroid Compounds from the Starfish Aphelasterias japonica of the Kuril Population
Authors: Kicha A. A. , Ivanchina N. V. , Kalinovsky A. I. , Dmitrenok P. S. , Stonik V. A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Carbopeptoids: Peptides and Diketopiperazines Incorporating the Anomeric Centre of Mannopyranose.
Authors: Long Daniel D. , Tennant‐Eyles Richard J. , Estevez Juan C. , Wormald Mark R. , Dwek Raymond A. , Smith Martin D. , Fleet George W. J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: From Peptides to Non‐Peptide Peptidomimetics: Design and Synthesis of New Piperidine Inhibitors of Aspartic Peptidases.
Authors: Bursavich Matthew G. , West Chris W. , Rich Daniel H.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel all‐cis‐functionalized Cyclopropane Template‐Assembled Collagen Models.
Authors: Yamazaki Shoko , Sakamoto Mari , Suzuri Michiko , Doi Masamitsu , Nakazawa Takashi , Kobayashi Yuji
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of New Oxamide Derivatives of D‐Glucosamine and Aliphatic or Aromatic Amines.
Authors: Temeriusz Andrzej , Piekarska‐Bartoszewicz Boguslawa , Rowinska Magdalena
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New General Synthesis of Isomeric Nucleosides.
Authors: Bera Sanjib , Nair Vasu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unexpected Results and Recourse in Process Optimization of Nucleoside 3′‐O‐Succinates
Authors: Song Quanlai , Sanghvi Yogesh S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies on Sialoglycoconjugates. Part 120. The First, Efficient Synthesis of Novel SLex Neoglycolipids Containing N‐Deacetylated and Lactamized Sialic Acid: Key Ligand Structures for Selectin Binding.
Authors: Otsubo Nobumasa , Yamaguchi Masanori , Ishida Hideharu , Kiso Makoto
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Enyne Metathesis Approach to the Synthesis of the 1,3‐Diene System of Mycothiazole.
Authors: Rodriguez‐Conesa Sara , Candal Paloma , Jimenez Carlos , Rodriguez Jaime
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of trans‐γ‐Oxo‐α,β‐unsaturated Carboxylic Acids, the Intermediates for Patulolide A and Pyrenophorin.
Authors: Davis K. Joju , Bhalerao U. T. , Rao B. Vittal
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in Antibody Catalysis of Cycloaddition Reactions
Authors: Tremblay Martin R. , Dickerson Tobin J. , Janda Kim D.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Coordination and Transformation of Arene Rings by Transition Metal Carbonyl Cluster Complexes
Authors: Brait Sabrina , Deabate Stefano , Knox Selby A. R. , Sappa Enrico
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photomagnetic and Magneto‐Optical Effects of Functionalized Metal Polycyanides
Authors: Ohkoshi Shin‐Ichi , Hashimoto Kazuhito
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Modern Sample Preparation Methods in Chemical Analysis
Authors: Theodoridis Georgis , Papadoyannis I. N.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thermodynamic Estimate of pKa Values of the Carboxylic Acids in Aqueous Solution with the Density Functional Theory
Authors: Zeng Yue , Qian Haiyan , Chen Xianglan , Li Zelin , Yu Shangci , Xiao Xiaoming
Published: June 2010

The 96 pKa values of 85 carboxylic acids in aqueous solution were calculated with the density functional theory method at the level of B3LYP/6‐31+G(d,p) and the polarizable continuum model (PCM) was used to describe the solvent. In the calculations of pKa values, the dissociation Gibbs free energies were directly calculated using carboxylic acid dissociation reactions in aqueous solution, i. e., no thermodynamic cycle was employed, which is different from the previous literatures. A highly significant correlation of R2=0.95 with a standard deviation (SD) of 0.36 between the experimental pKa values and the calculated dissociation Gibbs free energies [ΔG(calc.)] was found. The slope of pKa vs. (G(calc.)/(20303RT) is only 47.6% of the theoretically expected value, which implies that the ΔG(calc.) value from the theoretical calculation is larger than the actual one for all 85 carboxylic acids studied. Thus, by adding the 0.476 scaling‐factor into the slope, we can derive a reliably procedure that can reproduce the experimental pKa values of carboxylic acids. The pKa values furnished by this procedure are in good agreement with the experimental results for carboxylic acids in aqueous solution.
Synthesis, Characterization and Thermal Behaviors of 4‐Amino‐5‐nitro‐1,2,3‐triazole (ANTZ) and Its Derivatives
Authors: Wang Bozhou , Li Jizhen , Huo Huan , Fan Xuezhong , Fu Xiaolong , Zhou Cheng
Published: June 2010

4‐Amino‐5‐nitro‐1,2,3‐triazole (ANTZ) and its derivatives, such as 2‐(4‐amino‐5‐nitro‐1,2,3‐trazole‐1‐yl)‐1,3,5‐trinitrobenzene (T‐ANTZ) and 4‐amino‐5‐nitro‐1,2,3‐triazole (M‐ANTZ), were synthesized and characterized, whose structures were confirmed by IR, NMR and elemental analysis. The thermal behaviors of ANTZ, T‐ANTZ and M‐ANTZ were studied by the methods of DSC and TG‐DTG, and the results showed that there is an obvious melting process of ANTZ with melting point of 278.38°C, while there is no melting process in the thermal behavior of T‐ANTZ and M‐ANTZ (the derivatives of ATNZ).
Enantioselective Fluorescent Sensors for N‐Boc‐Protected Amino Acid Anions Based on BINOL
Authors: Xu Kuoxi , Bu Zhanwei , Huang Kejing , Zhao Jin , Wang Chaojie
Published: June 2010

The four novel derivatives of BINOL have been prepared and the structures of these compounds characterized by IR, MS, 1H and 13C NMR spectroscopy and elemental analysis. The enantioselective recognition of these receptors has been studied by fluorescence titration and 1H NMR spectroscopy. The receptors exhibited different chiral recognition abilities towards N‐Boc‐protected amino acid anions and formed 1:1 complexes between host and guest. Receptor s exhibit excellent enantioselective fluorescent recognition ability towards the amino acid derivatives.
Synthesis and Antitumor Activity of Ether Glycerophospholipids Bearing a Carbamate Moiety at the sn‐2 Position: Selective Sensitivity Against Prostate Cancer Cell Lines
Authors: Byun Hoe‐Sup , Bittman Robert , Samadder Pranati , Arthur Gilbert
Published: June 2010

Analogues of 1‐O‐hexadecyl‐sn‐3‐glycerophosphonocholine (compounds 1–4) or sn‐3‐glycerophosphocholine (compound 5) bearing a carbamate or dicarbamate moiety at the sn‐2 position were synthesized and evaluated for their antiproliferative activity against cancer cells derived from a variety of tissues. Although all of the compounds are antiproliferative, surprisingly the carbamates (1 and 2) are more effective against the hormone‐independent cell lines DU145 and PC3 than toward other cancer cell lines we examined. This selectivity was not observed with the dicarbamates (3 and 4). Phosphocholine carbamate analogue 5 is as effective against the prostate cancer cell lines as the corresponding phosphonocholine analogue 1. Cell death induced by 2′‐(trimethylammonio)ethyl 4‐hexadecyloxy‐3(R)‐N‐methylcarbamoyl‐1‐butanephosphonate (carbamate analogue 2) appeared to be mediated by apoptosis, as assessed by caspase activation and loss of mitochondrial membrane potential. The in vivo activity of 2 was evaluated in a murine prostate cancer xenograft model. Oral and intravenous administration showed that 2 is effective in inhibiting the growth of PC3 tumors in Rag2M mice. Our studies show that the glycerolipid carbamates reported herein represent a class of prostate‐cancer‐selective cytotoxic agents.
High response rate after intratumoral treatment with interleukin‐2
Authors: Weide Benjamin , Derhovanessian Evelyna , Pflugfelder Annette , Eigentler Thomas K. , Radny Peter , Zelba Henning , Pföhler Claudia , Pawelec Graham , Garbe Claus
Published: June 2010

BACKGROUND:

Systemic high‐dose interleukin‐2 (IL‐2) achieved long‐term survival in a subset of patients with advanced melanoma. The authors reported previously that intratumorally applied IL‐2 induced complete local responses of all metastases in >60% of patients. The objectives of the current study were to confirm those results in a larger cohort and to identify patient or regimen characteristics associated with response.

METHODS:

Patients with melanoma who had a median of 12 injectable metastases received intratumoral IL‐2 treatments 3 times weekly until they achieved clinical remission. The initial dose of 3 million international units was escalated, depending on the individual patient's tolerance.

RESULTS:

Forty‐eight of 51 patients were evaluable. Only grade 1/2 toxicity was recorded. A complete response that lasted ≥6 months was documented in 70% of all injected metastases. A complete local response of all treated metastases was achieved in 33 patients (69%), including 11 patients who had between 20 and 100 metastases. Response rates were higher for patients who had stage III disease compared with patients who had stage IV disease. No objective responses of distant untreated metastases were observed. The 2‐year survival rate was 77% for patients with stage IIIB/IIIC disease and 53% for patients with stage IV disease. Efficacy and survival did not differ between patients who had ≥20 lesions and patients who had <20 lesions.

CONCLUSIONS:

Intratumoral IL‐2 treatment elicited complete local responses in a high percentage of patients. Further studies will be required to investigate the mode of action of this treatment and its impact on survival. Cancer 2010. © 2010 American Cancer Society.
Role of Multipole Moments in Electric‐Field‐Induced Order of Dense Molecular Systems
Authors: Acebal Pablo , Carretero Luis , Blaya Salvador
Published: June 2010

A new model is developed to describe the orientational order of dense molecular systems under an applied external electric field as a function of the n‐particle distribution functions of a system under no external perturbation. From an approximation of this expression, the effects of several variables on this orientational order, such as the microscopic properties of the oriented molecules (the molecular geometry and multipole moments) and the solvent or matrix properties, are studied. The theoretical predictions show that, for a correct description of the orientational order, quadrupole and octupole moments must be included, as they play an important role in the orientational order achieved, depending on the molecular geometry. Furthermore, to verify the validity of the model, theoretical predictions are compared with experimental results, and show a good concordance.