bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-modal Cell Labelling for Quantification and Optimization of Stem Cell Delivery to Orthotopic Breast Tumors
Authors: Zaw Thin May , Bofinger Robin , Kostelec Tomas D. , Connell John , Patrick P. Stephen , Allan Helen , Hailes Helen C. , Tabor Alethea B. , Lythgoe Mark F. , J. Stuckey Daniel , Kalber Tammy L.
Published: April 2019

Stem cells have been utilized as anti-cancer agents due to their ability to home to and integrate within tumors. Methods to augment stem cell homing to tumors are being investigated with the goal of enhancing treatment efficacy. However, it is currently not possible to evaluate both cell localization and cell viability after engraftment, hindering optimization of therapy. In this study, luciferase expressing human adipocyte derived stem cells (ADSCs) were labelled with superparamagnetic iron oxide nanoparticles (SPIONs) conjugated to Indium-111 to produce cells with tri-modal imaging capabilities. ADSCs were administered intravenously (IV) or intracardially (IC) to mice bearing 4T1 orthotopic breast tumors. Cell fate was monitored serially using bioluminescence imaging (BLI) as a measure of cell viability, magnetic resonance imaging (MRI) for cell localization and single photon emission computer tomography (SPECT) for cell quantification. BLI/MRI/SPECT imaging revealed differences in whole body cell distribution between injection routes. BLI showed the presence of viable ADSCs within tumors as early as 1-hour post IC injection compared to 3 days post IV injection. SPECT data showed the percentage of ADSCs within tumors to be 2-fold higher after IC than IV at 5-hour post injection. Whereas, MRI confirmed the localization of SPION labelled cells in tumors after IC injection but not IV. Finally, histological analysis was used to validate engraftment of ADSC within tumor tissue. These findings demonstrate that multi-modal imaging can be used to evaluate the efficiency of stem cell delivery to tumors and that IC cell administration is more effective for tumor targeting.
Single-Molecule Imaging of Active Mitochondrial Nitroreductases using a Photo-Crosslinking Fluorescent Sensor
Authors: Thiel Zacharias , Rivera-Fuentes Pablo
Published: April 2019

Many biomacromolecules are known to cluster in microdomains with specific subcellular localization. In the case of enzymes, this clustering greatly defines their biological functions. Nitroreductases are enzymes capable of reducing nitro groups to amines and play a role in detoxification and pro-drug activation. Although nitroreductase activity has been detected in mammalian cells, the subcellular localization of this activity remains incompletely characterized. Here, we report a fluorescent probe that enables super-resolved imaging of pools of nitroreductase activity within mitochondria. This probe is activated sequentially by nitroreductases and light to give a photo-crosslinked adduct of active enzymes. In combination with a general photoactivatable marker of mitochondria, we performed two-color, threedimensional, single-molecule localization microscopy. These experiments allowed us to image the sub-mitochondrial organization of microdomains of nitroreductase activity.
Aplasia of the vagina and uterus (Mayer-Rokitansky-Kustner-Hauser syndrome): etiology, pathogenetic aspects and theory of the formation of defect (literature review)
Authors: Kruglyak D A , Buralkina N A , Ipatova M V , Batyrova Z K , Uvarova E V
Published: April 2019

The article provides data on the etiology and pathogenesis of genital malformation - vaginal and uterine aplasia (Mayer-Rokitansky-Kustner-Hauser syndrome) at the present stage.
Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress
Authors: Moreno David F , Parisi Eva , Yahya Galal , Vaggi Federico , Csikász-Nagy Attila , Aldea Martí
Published: April 2019

The precise coordination of growth and proliferation has a universal prevalence in cell homeostasis. As a prominent property, cell size is modulated by the coordination between these processes in bacterial, yeast, and mammalian cells, but the underlying molecular mechanisms are largely unknown. Here, we show that multifunctional chaperone systems play a concerted and limiting role in cell-cycle entry, specifically driving nuclear accumulation of the G1 Cdk–cyclin complex. Based on these findings, we establish and test a molecular competition model that recapitulates cell-cycle-entry dependence on growth rate. As key predictions at a single-cell level, we show that availability of the Ydj1 chaperone and nuclear accumulation of the G1 cyclin Cln3 are inversely dependent on growth rate and readily respond to changes in protein synthesis and stress conditions that alter protein folding requirements. Thus, chaperone workload would subordinate Start to the biosynthetic machinery and dynamically adjust proliferation to the growth potential of the cell.
Dol 222
Authors: NASCIMENTO PAULO GUSTAVO BARBONI DANTAS
Published: April 2019

DOL – Dor OnLine

 

EDIÇÃO 222

 

Chamada da Edição

 

Leitores do Dor On Line, nossa edição de janeiro de 2019 traz um interessante editorial sobre boas práticas para a experimentação animal. Além disso, selecionamos trabalhos sobre estudos da dor que foram apresentados no 50th Brazilian Congress of Pharmacology and Experimental Therapeutics, ocorrido em Ribeirão Preto, no período de 25 a 28 de setembro de 2018. Boa Leitura!

 

EDITORIAL DO MÊS

 

Utilização de animais em pesquisa: Iniciativas para promoção do bem-estar animal, aumento na qualidade dos dados e sua reprodutibilidade.

 

Adriele Alves Santos

Thayná Moreira Gomes Marra

Mani Indiana Funez

 

ALERTAS

 

1 - Antagonismo do receptor tipo 2 para angiotensina como tratamento do ataque agudo de gota.

Thiago Neves Vieira

 

2 - O Receptor de Potencial Transitório Ankirina 1 desempenha um papel crítico em um modelo animal de dor devido a metástase de câncer em camundongos

Priscilla Dias

 

3 - O envolvimento dos receptores P2X3 periféricos na dor muscular aguda, mas não na indução e manutenção da dor muscular crônica.

Alexandre Hashimoto Pereira Lopes

 

4 - Avaliação da eletroacupuntura e exercícios físicos em modelo de monoartrite em ratos

Alexandre Hashimoto Pereira Lopes

 

5 - O efeito antinociceptivo de compostos semi-sintéticos derivados de flores de Moringa oleífera é mediado pelos receptores P2X7 em um modelo pré-clínico de dor na articulação temporomandibular de ratos

Henrique Ballassini Abdalla

 

6 - Avaliação do efeito antinociceptivo da toxina TX3-3 isolada do veneno da aranha Phoneutria nigriventer no modelo de fibromialgia em camundongos

Dênis Augusto Sant'Anna dos Reis

 

7 - Ativação do PPAR-gama modula a diminuição da expressão gênica induzida pela cisplatina em um modelo de Neuropatia Periférica Induzida por Quimioterapia

Rangel Leal silva

 

8 - Investigação do envolvimento do sistema endocanabinoide na antinocicepção induzida por estimulação elétrica nervosa transcutânea

Andressa Daiane de Carvalho Zaparolli

 

9 - Dieta deficiente em zinco aumenta a dor nociceptiva, no entanto reduz a dor inflamatória.

Conceição Elidianne Anibal Silva

 

10 - Análise de vocalização ultra-sônica para o estudo do componente afetivo da dor orofacial aguda e do contágio emocional da dor em ratos

Erika Ivanna Araya Pallarés
Dol 223
Authors: NASCIMENTO PAULO GUSTAVO BARBONI DANTAS
Published: April 2019

Dol 223
Pacifismo, educação e dimensões políticas na América Latina: Cecília Meireles em diálogo com Alfonso Reyes (Rio de Janeiro, década de 1930)
Authors: Silva Denilson De Cássio
Published: April 2019

O artigo analisa as ideias em torno da questão da guerra e da paz, discutidas pela poetisa e jornalista carioca, Cecília Meireles, e Alfonso Reyes, embaixador do México no Brasil de 1930 a 1936. Tendo como principais fontes exemplares do Diário de Notícias, demonstra-se que ambos os intelectuais defenderam um pacifismo ativo, de tônica universalista, com base na valorização de uma educação nova e do protagonismo da América Latina.
O Estado Novo por Getúlio Vargas: a verdadeira democracia é a democracia social?
Authors: Meireles Junior Claudio Alcântara
Published: April 2019

O texto discute, a partir da reconstrução parcial do discurso oficial do regime do Estado Novo, utilizando-se como referência as falas públicas de Getúlio Vargas, de que maneira a retórica de tais manifestações entrelaçou autoritarismo e garantia de direitos sociais com o escopo argumentativo de reivindicação da ditadura como uma democracia social sob a tutela personalíssima do seu líder. Investiga-se no artigo, portanto, a construção, por meio do discurso, da concepção de uma cidadania atrelada ao trabalhador, mas sem exercício de liberdades políticas, o que, por si só, não significaria que o regime varguista seria antidemocrático, conforme a própria fala de Vargas. O governo estado novista reivindicou para si o caráter de democrático, não de uma democracia liberal, mas sim de uma espécie de democracia social.
Physical activity, approach-avoidance temperament and depressive symptoms
Authors: Cecchini Jose A. , Fernandez-Río Javier , Mendez-Gimenez Antonio
Published: April 2019

The goal was to assess the connections between
vigorous physical activity (VPA), approach-avoidance temperament and depressive
symptoms. Two studies were conducted. Study 1, correlational, to assess the mediating role of both dimensions of
temperament, approach-avoidance contrast, between physical activity and
depressive symptoms. Participants, 335
college students, completed the International Physical Activity
Questionnaire, the Depressive Symptoms Scale (DSS) and the Approach-Avoidance
Temperament Questionnaire (Ap-AvTQ). Results showed that approach-avoidance contrast could be considered a
potential mediator between VPA and depressive symptoms. The global model was significant, F(2, 351)=3.22, p<.001, R2=14.91%,
R2 adjusted=14.42%, and the bootstrapped upper and lower limits did
not contain zero with the lower limit at -.05 and the upper at -14, suggesting a connection between VPA and depressive
symptoms mediated by the approach-avoidance contrast temperament. Study 2,
longitudinal, to test if a physical activity program could produce changes in
approach-avoidance contrast temperament, manipulating the depressive symptoms.
A VPA program was conducted with 149 college students. Participants completed
the DSS and the Ap-AvTQ. The true intraindividual change modeling technique, a
more direct approach to modeling interindividual differences in intraindividual
change without using a control group, showed that participants’ depressive
symptoms were predicted through the mediation of the approach-avoidance contrast temperament (γ=-.36, p<.001). VPA was positively linked to the
approach-avoidance contrast temperament that was negatively connected to
depressive symptoms, and negatively linked to the approach-avoidance contrast temperament
that was positively connected to depressive symptoms. It seems possible to
influence depressive symptoms through approach-avoidance contrast temperament
using VPA.
ANALISIS DAN PEMODELAN INVERSI STRUKTUR BAWAH PERMUKAAN BERDASARKAN ANOMALI GRAVITASI PULAU LOMBOK
Authors: Hiden Hiden , SB Kirbani , S Wiwit , SH Danang
Published: April 2019

Sistem patahan, intrusi, dan daerah pengangkatan banyak terdapat di Pulau Lombok, tetapi secara visual tidak tampak di permukaan. Tujuan dari penelitian ini adalah menganalisis anomali gravitasi dan memodelkan struktur geologi bawah permukaan berdasarkan anomali gravitasi. Hasil penelitian menunjukkan korelasi yang baik antara karakteristik anomali Bouguer maupun anomali residual terhadap struktur yang telah diketahui di Pulau Lombok. Umumnya, anomali tinggi baik anomali Bouguer maupun anomali residu tinggi berkorelasi baik dengan singkapan zona Solo di sebelah barat, kerak magmatik tebal di sebelah timur dan area pengangkatan di selatan Lombok. Berdasarkan anomali residu tinngi, terdapat beberapa sesar lokal teridentifikasi dengan sangat jelas. Sementara anomali residu rendah tampak pada wilayah Kompleks Gunung Rinjani. Perkiraan sesar yang membelah dua Pulau Lombok (sesar Lombok: FL) tidak terbukti keberadaannya baik dengan anomali Bouguer, anomali residu maupun dengan pemodelan inversi 2D. Interpretasi hasil pemodelan inversi 2D menunjukan variasi batuan dengan densitas (2,625 – 2,858) kg/m3 yang terdistribusi secara spasial pada kedalaman (1,31 – 4,66) km.
PENGARUH PEMBERIAN PAKAN KEONG MAS TERHADAP PERTUMBUHAN DAN KELANGSUNGAN HIDUP LOBSTER PASIR (Panulirus homarus)
Authors: Anggraini Witari , Abidin Zaenal , Waspodo Saptono
Published: April 2019

Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian pakan keong mas terhadap pertumbuhan dan kelangsungan lobster pasir (Panulirus homarus). Penelitian ini menggunakan rancangan acak lengkap (RAL) dengan perlakuan; Perlakuan P1 (100 % ikan rucah sebagai control), P2 (50 % ikan rucah + 50 % keong mas segar), P3 (50 % ikan rucah + 50 % keong mas olahan), P4 (100 % keong mas segar), P5 (100 % keong mas olahan). Data yang diperoleh dianalisa menggunakan analysis of variance (ANOVA) dengan taraf nyata 5 % dan dilakukan uji Duncan dengan taraf nyata 5 % untuk mengetahui perlakuan yang terbaik. Berdasarkan hasil penelitian menunjukkan bahwa semua perlakuan memberikan pengaruh yang berbeda nyata (p< 0.05) terhadap pertumbuhan mutlak, pertumbuhan spesifik, rasio konversi pakan dan efisiensi pakan. Pemberian pakan 100 % keong mas segar merupakan perlakuan yang paling baik dibandingkan dengan perlakuan yang lainnya.
PENAMBAHAN GETAH PEPAYA (Carica papaya) PADA PAKAN PELET DENGAN DOSIS YANG BERBEDA UNTUK PERTUMBUHAN DAN KELANGSUNGAN HIDUP IKAN MAS (Cyprinus carpio)
Authors: Yulianti Sri , Nurliah Nurliah , Lestari Dewi Putri
Published: April 2019

Tujuan penelitian ini adalah untuk mengetahui pengaruh penambahan getah pepaya pada pakan pelet terhadap pertumbuhan berat mutlak, efisiensi pakan, kecernaan total dan kelangsungan hidup ikan mas. Penelitian ini menggunakan rancangan acak lengkap (RAL) dengan perlakuan : pakan tanpa penambahan getah (P0), penambahan getah 1% (P1), penambahan getah 2% (P2), penambahan getah 2,5% (P3), penambahan getah 3% (P4) dari bobot pakan yang diberikan. Data yang diperoleh dianalisis menggunakan ANOVA dengan taraf nyata 5%. Hasil penelitian menunjukkan bahwa penambahan getah pepaya pada pakan yang digunakan dalam penelitian ini tidak memberikan pengaruh signifikan terhadap pertumbuhan berat mutlak, efisiensi pakan, kecernaan total, dan kelangsungan hidup ikan mas. Akan tetapi, pertumbuhan berat mutlak, efisiensi pakan dan kecernaan total ikan mas yang diberi pakan dengan penambahan getah pepaya 1% memberikannilai  yang cenderung lebih tinggi dibandingkan dengan perlakuan yang lain.
The Authority Of Regional Government Of Formation Regional Regulation (Perda) Shari'a
Authors: Galang Asmara Muhammad , Dwi Hendro Wibowo Gatot , Cahyowati RR
Published: April 2019

The study, the Authority of regional government Formation of Regional Regulation (Perda) shari'a aims to assess four legal issues, namely: (1) Establish a Regional Authority Perda Syariah; (2) The criteria of Shariah legislation; (3) The procedure of Legislative Shari'ah; (4) Testing Regulation to shariah. This research is normative by using several approaches, namely: (a) Conceptual Approach (Conceptuan aproach); (B) Approaches Legislation (Statute aproach); and (c) Approach the case (Case aproach). The results of this study are expected bermenfaat either for the development of Science and to assist practitioners in the formation of legislation. The research results are as follows: (1) The Regional Authority to establish Sharia legislation can be found in several laws and regulations, both in the Constitution and in the implementation of such rules in the Act; (2) Criteria Sharia legislation is contained in the contents that are based on the values and teachings of Islam; (3) Procedures establishment of sharia in praktinya regulations following the establishment of regulations in general; (4) review of sharia regional regulation also follow the testing procedures and legislation in general. Forward suggest that the process of formation of Perda Syariah scholars to enroll in the area at least in the process of forming draft local regulations. Similarly, in the process of judicial review and evaluation should be based on the sources of Islamic law and involves an element of religious leaders and religious judges.
Et Tu Ru? Entrepreneurship and the Commodification of Drag in RuPaul’s Drag Race
Authors: Buck Jonathan
Published: April 2019

Historically, drag is a taboo which has been marginalized in the face of centuries of repression against non-heteronormative activity. Yet today drag has become highly visible in popular culture, and this is in large part attributable to the international success of American reality TV show RuPaul’s Drag Race (2009-present). Its bold representation of drag on a mainstream television show is unprecedented and the selection of drag queen competitors by the show’s producers has demonstrated a plethora of representations as Drag Race showcases a diverse range of identifications from the world of drag performance. The blossoming of Drag Race’s success comes at a historical moment in which we are seeing a huge proliferation of queer representations (re)produced in US television and other media over the last decade. However, as I will argue, the apparent liberalization of drag queens in popular culture is not simply a celebration of so-called ‘progress’ in the recognition of the marginalized, but may also be prompting the promotion of other value changes within late capitalism’s ideals of consumerism and entrepreneurship. Contestants are increasingly pressured to construct their drag performances to conform to a recognizable brand to reach the heights of their own private ‘success’. Mainstreamed depictions of queer subjects are susceptible to co-option, particularly in televisual forms such as Drag Race which prospers by channelling the emancipatory and subversive desires of the subculture. Through trans-textual considerations and historical contextualizations, I show how the representation of drag in Drag Race is depoliticized through neoliberal discourse as the show’s continual demand for competitors to ‘work it’ privileges and maintains the impetus for competitive profitmaking above the needs and demands of disempowered groups.
Supply Chain Flexibility and Financial Performance in the Emergent Market “Morocco case study”.
Authors: Rochdi Mohamed Houssam , Lemtaoui Morad , Raji Hajar
Published: April 2019

Today, and especially in the emergent market, the company success is directly linked to its capacity to deal with the highly changing environment, and how much its supply chain is flexible regarding these changes. The paper analyses how the supply chain flexibility impacts the firms’ financial performance in the emergent market, taking Morocco as a study case due to what this country demonstrated as economical resilience during the recent economic crisis and during the “Arab Spring”, by applying a multiple linear regression model. The result suggests that the supply chain flexibility has a significant impact on the firms’ revenue growth, confirming that today the supply chain flexibility is a key element in the company’s business sustainability.

JEL codes: G39, M11, O4,
The House Price Dynamics and the Macro-Economy: an Empirical Perspective of UAE
Authors: Al Zaabi Yahya Hamad , Bekele Genanew
Published: April 2019

Objective: The paper aims to examine house price drivers in Dubai, addressing the effect of internal and external factors afecting house prices

 

Design/methedology/approach: Using the Hedonic price model, the study examined the implications of house size (space), the availability of bathrooms, bedrooms, waterfronts, and pool and cell phone towers within residential area as auxiliary determinant factors to housing price within developed cities by using the Hedonic Modelling. Also, study highlight the effect of the green strategies that been followed by developer on the housing prices.

 

Findings: The study is expected to reveal results with significant ramifications for researchers, practitioners and policy makers. From a policy perspective, there is an obvious interest in understanding whether the price of housing is affected by different attributes differently along its distribution.

 

Research limitations/implications: The data used in this study could be limited, and depends on information to be provided by the Dubai Land Department. There is a room for future research to include more data (such as on other house attributes such as house condition, plot numbers and configuration).
Numerical aspects of business court specialization
Authors: Filho Fernando Correa , Trecenti Julio Adolfo Zucon , Nunes Marcelo Guedes
Published: April 2019

Jurisdiction specialization is a topic of interest in the administration the justice system. Pros and cons have been vastly discussed, but few papers discuss the pratical details connected to the application of this policy. In this study, we discuss the creation of business courts in the County of São Paulo Brazil, and introduce innovating data analysis methodologies for solving pratical problems. In São Paulo, new courts, specialized or not, must follow two main criteria. New courts must have a minimum number of lawsuits per year and must have some estimate of the future worka load. In the performed analyses, we found evidence that a business lawsuit requires almost twice the amount of effort of a common lawsuit. By correcting the volume of lawsuits, based on a matter-treatment model, we arrived at the conclusion that two business courts can handle the existing demand adequately. Also, we were able to develop a robust methodology to verify if and how business courts should be created.
The Study of Green Human Resource Management and its effect on employees’ health in Automobile Industry
Authors: Anuradha Anuradha , Srivastava A K
Published: April 2019

As of late, there has been an expanding mindfulness inside business networks on the essentialness of making strides toward environmental friendliness and receiving different condition management methods. As the corporate world is going worldwide, the business is encountering a move from a regular money related structure to a cutting edge limit based economy which is prepared to investigate green financial aspects of business. Today, Green Human Resource Management (GHRM) has turned into a key business methodology for the noteworthy associations where Human Resource Departments have a functioning influence in making strides toward environmental friendliness at the workplace. The main objective of this study is to review Green Human Resource Management and its effect on Employees Health in Automobile Industry. This study focuses on how and why Green Human Resource Management practices are implemented by different organizations. This study also reviews the negative and positive impacts of green-HRM practices on employee health and the employee commitment levels in organizations.
Towards a Sustainable Happiness Model for UAE: Lessons from Latin America
Authors: Nandagopal Vidya
Published: April 2019

Traditionally studies on Happiness have been using income as a proxy for wellbeing and quality of life using GDP to measure progress of nations. We need to understand here that while income is an objective measure, Happiness is a subjective measure. One of the key criticisms leveled against GDP is that it does not take into account sustainability. Sometimes growth may be there but not achieved through sustainable thereby risking the future. On the flip side economic growth itself may not be sustainable in some cases. So can we depend on economic factors alone to be happy? In the past decade or so more and more countries are looking at the “Beyond GDP “agenda. in 2011 the OECD developed a framework for measuring wellbeing that can reflect and support development of measurement frameworks on a national level. there are a sizeable number of Latin American countries scoring consistently high on the Happiness index despite a number of socio economic issues. The recently published World Happiness report (2018) suggests that this is not a mere coincidence. It is based on the fact that Happiness in Latin America has social foundations. UAE lists in the top 20 countries with a happiness index of 6.774. (Source: World Happiness ranking 2015-17).This is the first ever attempt to superimpose the Latin American happiness model on the UAE local community to arrive at a sustainable happiness model for them.
Banks’ Profitability Under Democratic & Dictatorship Regime: Evidence from Pakistan
Authors: AsadUllah Muhammad
Published: April 2019

The aim of the study is to find out the determinants of profitability of Pakistan Banking System under democratic and dictatorship regime, i.e. 2006-2008 and 2009-2011 respectively. The authors were taken macroeconomic variables, i.e. GDP, Inflation and Interest Rate and bank-specific variables, i.e. Liquidity, size and capital adequacy as independent variables whereas Return on Asset as the dependent variable. By employing panel regression, the authors found that size has a significant negative relationship with profitability under both regimes. Interest and Liquidity had a positive significant relationship during democratic tenure. However, liquidity had significantly negative relationship between dictatorship duration. The findings will be helpful for the banking sector to make their policies accordingly.
Turismo nas fazendas de criação de gado do Pantanal
Authors: Araujo Ana Paula Correia de , Vargas Icléia Albuquerque de
Published: April 2019

O artigo apresenta uma reflexão sobre o turismo nas fazendas de gado do Pantanal de Mato Grosso do Sul discutindo a adaptação da região para o atendimento de exigências impostas pelos paradigmas da sustentabilidade socioambiental. O objetivo do trabalho foi compreender os processos que promoveram o avanço de sistemas considerados sustentáveis nas fazendas tradicionais do Pantanal. A investigação se deu a partir de levantamento de dados de natureza primária, coletados juntos aos empresários do turismo, pecuaristas, associações e trabalhadores, utilizando-se de questionários e de entrevistas semi-estruturadas. Foi possível constatar a transformação de fazendas em fazendas-hotéis, buscando diversificar a fonte de renda para manter suas sobrevivências, adotando assim, a multifuncionalidade das unidades produtivas, ao mesmo tempo em que atendem à crescente demanda de potenciais turistas, do Brasil e do exterior, que desejam conhecer e viver momentos especiais no Pantanal.
A inserção do bacharel em turismo no setor de alimentos e bebidas: um estudo dos restaurantes associados da abrasel Campo Grande – MS
Authors: Silva Andressa Moraes , Minohara Rodrigo Hakira , Oliveira Luana De Sousa
Published: April 2019

Este artigo tem como objetivo analisar a inserção dos bacharéis em Turismo egressos da UEMS no setor de Alimentos e Bebidas, com base em dados dos restaurantes associados da Abrasel em Campo Grande/MS.  Este estudo é de caráter qualitativo e exploratório, que fez o uso de pesquisa de campo, a qual teve como ferramenta entrevistas estruturadas realizadas com os gestores dos restaurantes associados, as quais foram analisadas a partir o método de análise do Discurso do Sujeito Coletivo (DSC). Os resultados apontaram que as competências, conhecimentos e habilidades do bacharel em turismo são correspondentes às expectativas no mercado. Entretanto, uma grande parte dos gestores desconhecem a profissão e papel que o turismólogo pode desempenhar nos mais diversos empreendimentos.
Análise do turismo sob o enfoque sistêmico: estudo de caso do território turístico de fronteira - Pedro Juan Caballero/PY e Ponta Porã/BR
Authors: Ribeiro Veridiana , Grechi Dores Cristina
Published: April 2019

Este estudo utilizou a Teoria Geral de Sistemas para analisar o turismo num território de fronteira entre Brasil e Paraguai. De forma inicial realizou-se uma revisão teórica dos autores que já estudaram esta teoria aplicada para o turismo, identificando semelhanças e aspectos complementares entre os mesmos. A pesquisa preocupou-se, ainda, em verificar a aplicabilidade da abordagem sistêmica como método de análise, usando como exemplo o sistema turístico de Mato Grosso do Sul no território de fronteira, especialmente os municípios irmãos, Pedro Juan Caballero/PY e Ponta Porã/BR. A metodologia baseou-se em pesquisa bibliográfica e documental. A partir da consulta em livros, artigos, periódicos e sites institucionais foi possível identificar os elementos do sistema turístico de fronteira e seu respectivo modelo, o qual configura-se num formato único, por ser binacional.
A mulher pantaneira no contexto das fazendas de turismo
Authors: Thomé Pollianna
Published: April 2019

O turismo configura-se como a atividade econômica que mais cresce no Pantanal brasileiro, região onde há predominância da propriedade privada da terra para criação de gado bovino. Em sobreposição ou substituição à pecuária, a atividade turística atua sobre a dinâmica das fazendas. Esta pesquisa tem o objetivo de mostrar que entre as mudanças observadas está o papel da mulher na sociedade pantaneira, cujo trabalho ganhou maior importância nas fazendas por desempenhar atividades essenciais para o turismo como o serviço de alimentação dos turistas e a limpeza e arrumação dos quartos. Através da observação participante, foi diagnosticado o universo feminino em quatro fazendas que atuam com turismo na Região do rio Negro, no município de Aquidauana/MS, assim como entrevistas não-diretivas foram feitas com proprietários, turistas, funcionárias e familiares. Os resultados da pesquisa demonstram que a presença do turismo modifica hábitos de consumo das mulheres; aumenta sua autonomia em relação à família; intensifica a sua ligação com os centros urbanos, pois é de lá que provém muitas delas e é para as cidades que dirigem muitos de seus interesses. Por último, ao alterar o status da trabalhadora no Pantanal, o turismo interfere diretamente na questão da identidade pantaneira, até então centrada no universo masculino.
Denizli Horozu ve Tavuğu (Gallus Gallus Domesticus) ile Sülün (Phasianus Colchisus) Sirinks’lerinde Bağ Dokusu Fibrillerinin Dağılımı
Authors: ÇINAR Kenan
Published: April 2019

Bu çalışmada Denizli horozu ve tavuğu (Gallus gallus domesticus) ile sülün (Phasianus colchisus) sirinkslerinde bağ
dokusu fibrillerinin dağılımı ve düzenlenmelerinin belirlenmesi amaçlandı. Bu
amaçla 4’er adet erişkin Denizli horozu ve tavuğu ile dişi ve erkek sülünlerden
alınan sirinksler materyal olarak kullanıldı. Denizli horozunda kollagen
fibrillerin LTM (Lateral Timpanik Membran) lamina propriasından submukozaya
doğru geniş bir alanda kalın demetler halinde olduğu; özellikle tunika serozaya
yakın submukozada  çok daha sıkı biçimde
yerleşim gösterdikleri saptandı. MTM (Medial Timpanik Membran)  lamina propriasında kollagen fibrillere
nazaran daha geniş bir alanda kalın fibriller şeklinde yerleşim gösteren
elastik fibrillerin Denizli tavuğunda submukozaya doğru daha yoğun biçimde
düzenlendikleri gözlendi. Erkek sülünlerde LTM’a ait lamina propriada,
bronşiyal kıkırdak halkalar arasında ve pessulus lateralindeki lamina propriada
kollagen fibrillerin sıkı biçimde bir araya gelerek ince demetler oluşturduğu
gözlendi.
Análisis territorial del desempleo por género en la Comunidad de Madrid durante la crisis (2008-2014)
Authors: Rodríguez Moya Juana María , Pozo Rivera Enrique
Published: April 2019

Desde hace décadas la problemática de género ha cobrado un notable protagonismo, pero hay una escasez de estudios que aborden la cuestión del género en el ámbito territorial, y más en el contexto temporal actual de profunda crisis económica. En esta contribución se estudian las características y evolución del desempleo según género en La Comunidad de Madrid en el periodo 2008-2014. El trabajo se divide en dos partes: en la primera se estudia la caracterización del desempleo según género en relación con algunas variables sociodemográficas. En la segunda se adopta una perspectiva espacial: se reconocen las diferencias intermunicipales en el ritmo de crecimiento del paro de hombres y mujeres durante los últimos años y también los patrones de distribución espacial por género en la Comunidad de Madrid. Por último, se aplican técnicas de análisis estadístico espacial que permiten detectar estructuras espaciales del desempleo femenino y su comparación con el caso de los hombres. Los resultados confirman que, a pesar de haber descendido la brecha de género en el desempleo, persisten grandes diferencias espaciales.
Desarrollo turístico inclusivo socialmente. El caso de los desmovilizados en la región del Chocó, Colombia
Authors: Crespi-Vallbona Montserrat , Galeas Ortiz Sofía Alexandra , López Zuñiga María Alejandra
Published: April 2019

El turismo en Colombia constituía una aventura y riesgo durante el periodo de guerra con las FARC (1966-2016). Tal conflicto interno ocasionó una relevante fragmentación territorial que impidió su desarrollo, dejando muchas zonas intactas utilizadas para el resguardo de estas fuerzas armadas. Ahora, tras el acuerdo de paz (2016), y gracias al buen estado de esta área del territorio, se abren oportunidades para aprovechar sus recursos naturales. También para el proceso de desmovilización. Los desmovilizados cuando dejan las armas, ingresan voluntariamente al proceso de reintegración social. Uno de estos canales de reinserción es la inclusión laboral. Sin embargo, esta inclusión presenta una cierta quimera. Las empresas del sector privado tienden a frenar el acceso de las personas desmovilizadas al trabajo. Igualmente, reside también en la sociedad una actitud de rechazo hacia ellos. El objetivo de la investigación es diseñar un modelo de desarrollo turístico sostenible basado en la inclusión social que surja como respuesta a las necesidades de los desmovilizados de las FARC y de los desplazados por la violencia en Colombia, concretamente en el Departamento o región del Chocó. El objetivo último es promover la integración social y la revitalización económica de este territorio.
Design lifelong education using massive open online courses
Authors: Хохлова Марина , Hohlova Marina , Трутнев Олег , Trutnev Oleg
Published: April 2019

The possibilities of lifelong education through the use of open education technologies at the national and international levels are considered. Modern services offered by various platforms of mass open online courses are presented.
Educational discipline "design of advertising" in the educational space of the construction college
Authors: Куличенко Александр , Kulichenko Alexander , Рак Екатерина , Rak Ekaterina , Зайцева Анастасия , Zaitseva Anastasiya
Published: April 2019

Approaches to the actual academic discipline "advertising Design" as graphic design, advertising and marketing are proposed. The important factors of professionalism, advertising designer taking into account the requirements of the modern market are highlighted. The structure and stages of design planning of elements of an interior of educational space are offered.
ANALISIS PENERAPAN KMK NOMOR 1981 TAHUN 2010 TENTANG PEDOMAN AKUNTANSI BADAN LAYANAN UMUM-RUMAH SAKIT PADA LAPORAN KEUANGAN BLUD RSUD CIMACAN
Authors: Susandra Farizka , Yusuf Muhammad
Published: April 2019

Penelitian ini bertujuan untuk mengetahui penerapan dalam penyajian laporan keuangan RSUD Cimacan berstatus PPK-BLUD penuh dengan mengacu pada Keputusan Menteri Kesehatan (KMK) No.1981/2010 Tentang Pedoman Akuntansi Badan Layanan Umum-Rumah Sakit disetujui Menteri Keuangan dengan No. S-5342/MK.5/2010. Analisis data bersifat deskriptif kualitatif dengan metode komparatif yaitu membandingkan penerapan atas penyajian informasi laporan keuangan yang telah disusun RSUD Cimacan dengan laporan keuangan berdasarkan KMK No.1981 Tahun 2010. Komponen lengkap laporan keuangan terdiri dari neraca, laporan operasional, laporan arus kas & CaLK. Hasil penelitian menunjukan bahwa penyajian pada laporan keuangan RSUD Cimacan berstatus BLUD penuh secara garis besar telah sesuai dengan KMK No. 1981/2010 dalam menyajikan laporan keuangan, namun belum menyajikan laporan arus kas berbasis Standar Akuntansi Pemerintah (SAP) yang disesuaikan didalam PP No.71/2010 untuk entitas pelaporan pada keuangannya dalam hal konsolidasi, juga sebagai kebutuhan untuk pihak berkepentingan.
ANALISIS PENERAPAN KARAKTER PEDULI LINGKUNGAN MELALUI PROGRAM SEKOLAH BERBASIS ALAM
Authors: Nurellah Andea , Sumantri M Syarif , Purwanto Agung
Published: April 2019

Penelitian ini bertujuan untuk mengetahui penerapan karakter peduli lingkungan melalui program sekolah berbasis alam di internasional green school sumedang. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif kualitatif. Data dari penelitian ini adalah hasil observasi dan wawancara. Hasil dan kesimpulan penelitian mengungkapkan bahwa: (1) strategi penerapan karakter nilai peduli lingkungan siswa diterapkan melalui program pengembangan diri, pengintegrasian dalam mata pelajran, program sekolah,dan pengembangan proses, (2) peran lembaga pemerintah dalam perencanaan dan pelaksanaan penerapan karakter peduli lingkungan yaitu dengan menjalin kerjasama, (3) faktor pendukung penerapan karakter nilai peduli lingkungan di Internasional Green School Sumedang yaitu sekolah dan guru sudah melakukan pembiasaan, sedangkan faktor penghambatnya yaitu kurangnya kerjasama orang tua dalam menerapkan karakter peduli lingkungan di rumah dan konentrasi siswa terganggu apabila situasi pembelajaran yang diakukan di luar kelas terlalu ramai.
PROGRAM SOSIALISASI PENDIDIKAN UNTUK MENINGKATKAN ANGKA HARAPAN LAMA SEKOLAH (HLS)
Authors: Wulandari Ratna Wahyu , Kholik Abdul , Qudsiyah Mahbarotul , Agustian Rian
Published: April 2019

Program Sosialisasi Pendidikan merupakan kegiatan pengabdian kepada masyarakat dalam rangka membantu pemerintah Kabupaten Bogor untuk meningkatkan Angka Harapan Lama Sekolah (HLS) anak-anak terhadap pendidikan formal. Kegiatan ini berbentuk serangkaian kegiatan yang terdiri dari sosialisasi minat belajar di PAUD, sosialisasi wajib belajar 12 tahun, pengadaan taman baca, dan kegiatan bimbingan belajar. Tujuan dari kegiatan ini antara lain (1)  meningkatkan minat masyarakat terhadap PAUD; (2) meningkatkan minat masyarakat terhadap pendidikan formal;  (3) meningkatkan literasi pengetahuan dengan membaca; dan (4) meningkatkan aktivitas peserta didik di bidang pendidikan. Ada beberapa langkah yang dilakukan untuk melaksanakan kegiatan pengabdian ini, yaitu (1) analisis situasi, adalah kegiatan yang dilakukan untuk mengumpulkan data hasil observasi serta melakukan pemetaan permasalahan; (2) perancangan kegiatan, dilakukan setelah permasalahan diketahui dan dipetakan kemudian merumuskan solusi tepat yang akan diterapkan; dan (3) pengimplementasian kegiatan, dilakukan sesuai dengan rencana yang telah disusun. Sosialisasi ini memberikan dampak kepada masyarakat dalam bentuk motivasi pendidikan dan aktivitas pemberdayaan masyarakat.
CAPACITY BUILDING PADA UNIT PROGRAM PEMBINAAN KESEJAHTERAAN KELUARGA (PKK)
Authors: Rahmawati Agustina , Nugroho Hanantyo Sri
Published: April 2019

Desa Karangasem RT 05 RW 12 merupakan salah satu desa di Kelurahan Condong Catur yang padat penduduk dan masih memiliki area sawah yang cukup luas. Mata pencaharian sebagian besar kaum pria disana karyawan dan buruh tani, sedangkan mayoritas kaum wanitanya sebagai ibu rumah tangga. Sejak dahulu dicanangkannya Program Pembinaan Kesejahteraan Keluarga (PKK) ibu-ibu RT 04 RW 12 masih aktif, hingga sekarang terdapat Unit Program Bank Sampah dan Kelompok Wanita Tani (KWT) yang dibentuk Pemerintah. Namun, pada pengelolaannya masih belum optimal terutama pada unit KWT. Di dalam unit KWT menurut Ketua PKK Bu Sri Asmoroning masih terdapat kekurangan dalam internal organisasi yakni pada tata kelola administrasi dan kesekretariatan yang masih kurang tertib seperti sistem surat menyurat maupun laporan pembukuan. Adapula pada unit KWT kepengurusan organisasi telah terbentuk namun belum memiliki pembagian kerja yang jelas. Atas dasar itu, diperlukan pelatihan administrasi dan kesekretariatan sebab organisasi kelompok masyarakat miniatur organisasi yang sesungguhnya di masyarakat, maka sebagai penggiatnya harus belajar mengelola organisasinya secara profesional. Metode yang digunakan dalam pengabdian masyarakat ini yakni melalui ceramah dan tutorial pendampingan. Luaran kegiatan ini yakni adanya peningkatan kemampuan dan skill pengurus organisasi dalam mengelola administrasi dan kesekretariatan serta adanya pembagian kerja yang jelas dalam struktur organisasi KWT sehingga tercipta tanggungjawab dan wewenang yang efektif dalam kepengurusannya. Kedua hal tersebut merupakan instrumen Capacity Building fungsi penunjang kelancaran pelaksanaan tugas- tugas organisasi yang dilakukan oleh SDM pengelola unit program.
PROGRAM PENINGKATAN PENDAPATAN MASYARAKAT DESA MELALUI PEMANFAATAN LIMBAH KULIT PISANG MENJADI PRODUK KULIT PISANG ANEKA RASA DI DESA TUGU SELATAN KECAMATAN CISARUA KABUPATEN BOGOR
Authors: Maesaroh Siti , Kurnia Tuti
Published: April 2019

Tujuan dari pengabdian kepada masyarakat, dilakukan agar masyarakat dapat memanfaatkan limbah kulit pisang menjadi sebuah produk yang memiliki nilai jual, sehingga dapat meningkatkan pendapatan masyarakat Desa Tugu Selatan. Indikator capaian minimalnya memiliki pemahaman untuk memanfaatkan limbah kulit pisang. Target sasaran dari program pemanfaatan limbah kulit pisang yaitu masyarakat Desa Tugu Selatan, khususnya Kampung Sampay dan Kampung Rawadulang. Metode yang digunakan pada pengabdian kepada masyarakat ini yaitu menggunakan metode penyuluhan dan workshop (pelatihan), tentang tata cara pembuatan produk dari limbah kulit pisang seperti pangsit kulit pisang (PAKUPIS). Hasil dari kegiatan pengabdian kepada masyarakat yaitu masyarakat memiliki antusias untuk mengetahui dan mendapatkan pengetahuan tentang pengelolaan limbah kulit pisang, dapat dilihat dari banyaknya jumlah peserta yang mengajukan pertanyaan dan masyarakat menginginkan tindak lanjut seperti adanya program penyuluhan yang berkaitan dengan program tersebut.
PENGGUNAAN INTERNET PADA SISWA SMK GALILEO DESA KADUMANGGU
Authors: Filtania Melyani , Ratnamulyani Ike Atikah
Published: April 2019

SMK Galilelo merupakan satu-satunya sekolah menengah kejuruan yang ada di Desa Kadumanggu, Kecamatan Babakan Madang, Kabupaten Bogor, yang sangat peduli akan perkembangan jaman dan keterikatannya dengan dunia pendidikan. Salah satunya dengan penggunaan internet untukkomunikasi virtual yang menunjang proses belajar mengajar di sekolahan swasta tersebut. Ketersediaan internet inipun dimanfaatkan dengan baik oleh para siswa untuk meningkat prestasi baik dibidang akademik maupun diluar akademik. Oleh karena itu peneliti memiliki tujuan (1) Untuk mengetahui sejauh mana penggunaan internet di SMK Galilelo (2) Untuk mengetahui dampak internet terhadap proses belajar mengajar di SMK Galilelo (3) Untuk menganalisis pengaruh dengan prestasi belajar siswa SMK Galilelo. Metode penelitian ini bersifat kuantitatif deskriptif, dengan cara observasi, menyebarkan kuesioner, wawancara dan Teknik dokumentasi. Hasil penelitian menunjukan bahwa penggunaan internet di SMK Galileo dapat dikatakan optimal karena dalam proses belajar mengajar sangat berpengaruh dengan prestasi siswa.
PEMBERDAYAAN MASYARAKAT KAMPUNG WANGUN TENGAH, KELURAHAN SINDANGSARI, KECAMATAN BOGOR TIMUR, KOTA BOGOR MELALUI PENDIRIAN LEMBAGA KEUANGAN MIKRO SYARIAH DI PONDOK PESANTREN
Authors: Trihantana Rully , Alhifni Anas , Brawijaya Andri , Thantawi T.Rifqy , Paramita Metti
Published: April 2019

Pondok Pesantren merupakan lembaga pendidikan yang keberadaannya tidak dapat dipisahkan dari proses pertumbuhan dan perkembangan masyarakat. Pondok pesantren saat ini telah berkembang dan memberikan sistem pembelajaran yang berimbang antara aspek keagamaan dan IPTEK, bahkan banyak pesantren yang sudah memiliki kegiatan ekonomi seperti koperasi, BMT, pertanian, peternakan dan sebagainya. Namun terdapat kelemahan dalam manajemen pengelolaan sektor-sektor yang dapat menghasilkan profit, sehingga sangat diperlukan sebuah wadah berupa lembaga intermediasi yang dapat menjadi penghubung pondok pesantren yang memiliki sektor-sektor potensial dengan masyarakat melalui pendirian sebuah Lembaga Keuangan Mikro Syariah (LKMS). Kegiatan Program Kemitraan Masyarakat ini melibatkan dua kelompok masyarakat yaitu masyarakat yang ada di pesantren terdiri dari santri dan asatidz serta masyarakat di wilayah sekitar pesantren yang akan memanfaatkan keberadaan LKMS di pesantren Al Umm. Kegiatan yang telah dilakukan antara lain sosialisasi, pelatihan dan pendampingan. Sosialisasi diberikan kepada pihak pesantren dan masyarakat sekitar yang menjelaskan tentang kegiatan PKM ini, pelatihan pendirian dan pengelolaan LKMS dengan bentuk koperasi syariah, pendampingan bagi masyarakat untuk inovasi produk serta pendampingan untuk pengelolaan koperasi syariah. Hasil pelaksanaan kegiatan menunjukkan adanya minat untuk mendirikan koperasi syariah dan memanfaatkannya untuk mendukung usaha baik usaha pesantren maupun masyarakat.
TUGAS 2 TAHAPAN PENGAMBILAN KEPUTUSAN A.N YUNI WARDATUL INDRIANI SISTEM INFORMASI (KS) 2018)
Authors: Indriani Yuni Wardatul
Published: April 2019

Tujuan penelitian ini adalah untuk mengetahui dan menganalisis pengaruh motivasi, persepsi dan sikap konsumen terhadap keputusan pembelian. Satuan unit/obyek analisis penelitian ini adalah konsumen atau pembeli dan pengguna sepeda motor merek Honda di Kawasan Surabaya Barat. Dari hasil penelitian diketahui bahwa motivasi, persepsi, sikap konsumen berpengaruh secara positif dan signifikan terhadap keputusan pembelian sepeda motor merek Honda. Manfaat penelitian ini dapat dipakai sebagai informasi dalam usaha untuk meningkatkan volume penjualan melalui perilaku konsumen.
Penanganan Resiko Bawaan (Inherent Risk) Pada Auditsistem Informasi
Authors: SUWARNO MUJI
Published: April 2019

Audit atas laporan keuangan, di samping risiko audit, auditor juga akan menghadapi risiko lainnya seperti risiko kerugian praktek profesionalnya akibat dari tuntutan pengadilan, publikasi negatif, atau peristiwa lain yang mungkin timbul berkaitan dengan audit atas laporan keuangan yang dilakukan.Auditor harus selalu mempertimbangkan faktor risiko audit baik dalam tahap perencanaan audit, perancangan prosedur audit maupun dalam tahap evaluasi kewajaran penyajian laporan keuangan perusahaan.
An open essay on open science
Authors: Lobo Matheus Pereira
Published: April 2019

This is an open microarticle. We are issuing an open invitation for new contributions to this article in order to join forces and strengthen the field of openness of science and to promote a worldwide culture that might lead to unprecedented growth of scientific discoveries, which may spark a permanent revolution in science and technology in the near future. The guidelines for participating in this open project by co-authoring this work are described herein. Open Science (in any field of knowledge) can succeed extraordinarily solely by virtue of two simple elements: people willing to collaborate and a suitable online platform. We believe that science would progress substantially if we unite open researchers worldwide using nowadays technology in a clever way so that the results meet the standards required for high-level publications demanded by our current society. We present a simple way to accomplish "Open Science in Open Access Forums."
How Julia Perez Use Her Erotic Capital?
Authors: Safaningrum Anggi Cecilia , Rianzi Azka Felicia , Zein Laila Fariha , Setiawan Adib Rifqi
Published: April 2019

Women's studies work on sexuality generally focuses on sexual harassment or workplace romance to the exclusion of strategic forms of erotic capital. We consider women’s strategic sexual performances as a form of social influence and address the positive and negative consequences that may follow. This review highlights the occurrence and complexities of erotic capital in Julia Perez's musical performances nor modelling career and discusses the important implications of use her erotic capital (i.e. breast and ass) to influence others or gain desired ends. In so doing, the findings highlight a need for rethinking traditional conceptualizations of empowerment whereby resistance equals empowering and reproduction equals disempowering, and initiates a new direction for feminist scholarship in this regard.