bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Glucocorticoids Antagonize Estrogens by Glucocorticoid Receptor–Mediated Activation of Estrogen Sulfotransferase
Authors: Gong Haibiao , Jarzynka Michael J. , Cole Timothy J. , Lee Jung Hoon , Wada Taira , Zhang Bin , Gao Jie , Song Wen-Chao , DeFranco Donald B. , Cheng Shi-Yuan , Xie Wen
Published: April 2023

Supplementary Figure 1 from Glucocorticoids Antagonize Estrogens by Glucocorticoid Receptor–Mediated Activation of Estrogen Sulfotransferase
Supplementary Table C from Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215
Authors: Georges Sara A. , Biery Matthew C. , Kim Soo-yeon , Schelter Janell M. , Guo Jane , Chang Aaron N. , Jackson Aimee L. , Carleton Michael O. , Linsley Peter S. , Cleary Michele A. , Chau B. Nelson
Published: April 2023

Supplementary Table C from Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215
Supplementary Table A from Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215
Authors: Georges Sara A. , Biery Matthew C. , Kim Soo-yeon , Schelter Janell M. , Guo Jane , Chang Aaron N. , Jackson Aimee L. , Carleton Michael O. , Linsley Peter S. , Cleary Michele A. , Chau B. Nelson
Published: April 2023

Supplementary Table A from Coordinated Regulation of Cell Cycle Transcripts by p53-Inducible microRNAs, miR-192 and miR-215
Supplementary Figure 6 from Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival
Authors: Ramachandran Vijaya , Arumugam Thiruvengadam , Wang Huamin , Logsdon Craig D.
Published: April 2023

Supplementary Figure 6 from Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival
Supplementary Video 1 from Protein Kinase A Effects of an Expressed PRKAR1A Mutation Associated with Aggressive Tumors
Authors: Meoli Elise , Bossis Ioannis , Cazabat Laure , Mavrakis Manos , Horvath Anelia , Stergiopoulos Sotiris , Shiferaw Miriam L. , Fumey Glawdys , Perlemoine Karine , Muchow Michael , Robinson-White Audrey , Weinberg Frank , Nesterova Maria , Patronas Yianna , Groussin Lionel , Bertherat Jérôme , Stratakis Constantine A.
Published: April 2023

Supplementary Video 1 from Protein Kinase A Effects of an Expressed PRKAR1A Mutation Associated with Aggressive Tumors
Supplementary Information from Methylation of Polycomb Target Genes in Intestinal Cancer Is Mediated by Inflammation
Authors: Hahn Maria A. , Hahn Torsten , Lee Dong-Hyun , Esworthy R. Steven , Kim Byung-wook , Riggs Arthur D. , Chu Fong-Fong , Pfeifer Gerd P.
Published: April 2023

Supplementary Information from Methylation of Polycomb Target Genes in Intestinal Cancer Is Mediated by Inflammation
Supplementary Table 1 from Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
Authors: Chiche Johanna , Ilc Karine , Laferrière Julie , Trottier Eric , Dayan Frédéric , Mazure Nathalie M. , Brahimi-Horn M. Christiane , Pouysségur Jacques
Published: April 2023

Supplementary Table 1 from Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
Supplementary Figure 6 from Pericentromeric Instability and Spontaneous Emergence of Human Neoacrocentric and Minute Chromosomes in the Alternative Pathway of Telomere Lengthening
Authors: Gagos Sarantis , Chiourea Maria , Christodoulidou Agni , Apostolou Eftichia , Raftopoulou Christina , Deustch Samuel , Jefford Charles-Edward , Irminger-Finger Irmgard , Shay Jerry W. , Antonarakis Stylianos E.
Published: April 2023

Supplementary Figure 6 from Pericentromeric Instability and Spontaneous Emergence of Human Neoacrocentric and Minute Chromosomes in the Alternative Pathway of Telomere Lengthening
Supplementary Figure 6 from Identification of p18INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme
Authors: Solomon David A. , Kim Jung-Sik , Jenkins Sultan , Ressom Habtom , Huang Michael , Coppa Nicholas , Mabanta Lauren , Bigner Darell , Yan Hai , Jean Walter , Waldman Todd
Published: April 2023

Supplementary Figure 6 from Identification of p18INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme
Supplementary Methods and Materials from Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor β1– and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer
Authors: Geismann Claudia , Morscheck Mascha , Koch Dorothee , Bergmann Frank , Ungefroren Hendrik , Arlt Alexander , Tsao Ming-Sound , Bachem Max G. , Altevogt Peter , Sipos Bence , Fölsch Ulrich R. , Schäfer Heiner , Müerköster Susanne Sebens
Published: April 2023

Supplementary Methods and Materials from Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor β1– and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer
Supplementary Figure Legends 1-6 from Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor β1– and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer
Authors: Geismann Claudia , Morscheck Mascha , Koch Dorothee , Bergmann Frank , Ungefroren Hendrik , Arlt Alexander , Tsao Ming-Sound , Bachem Max G. , Altevogt Peter , Sipos Bence , Fölsch Ulrich R. , Schäfer Heiner , Müerköster Susanne Sebens
Published: April 2023

Supplementary Figure Legends 1-6 from Up-regulation of L1CAM in Pancreatic Duct Cells Is Transforming Growth Factor β1– and Slug-Dependent: Role in Malignant Transformation of Pancreatic Cancer
Supplementary Figure 1 from Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
Authors: Li Yiwei , VandenBoom Timothy G. , Kong Dejuan , Wang Zhiwei , Ali Shadan , Philip Philip A. , Sarkar Fazlul H.
Published: April 2023

Supplementary Figure 1 from Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
Supplementary Movie 3 from Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
Authors: Pinner Sophie , Jordan Peter , Sharrock Kirsty , Bazley Laura , Collinson Lucy , Marais Richard , Bonvin Elise , Goding Colin , Sahai Erik
Published: April 2023

Supplementary Movie 3 from Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
Supplementary Movie 2 from Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
Authors: Pinner Sophie , Jordan Peter , Sharrock Kirsty , Bazley Laura , Collinson Lucy , Marais Richard , Bonvin Elise , Goding Colin , Sahai Erik
Published: April 2023

Supplementary Movie 2 from Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination
Supplementary Table Legends 1- 3 from Sample Type Bias in the Analysis of Cancer Genomes
Authors: Solomon David A. , Kim Jung-Sik , Ressom Habtom W. , Sibenaller Zita , Ryken Timothy , Jean Walter , Bigner Darell , Yan Hai , Waldman Todd
Published: April 2023

Supplementary Table Legends 1- 3 from Sample Type Bias in the Analysis of Cancer Genomes
Supplementary Table 1 from Sample Type Bias in the Analysis of Cancer Genomes
Authors: Solomon David A. , Kim Jung-Sik , Ressom Habtom W. , Sibenaller Zita , Ryken Timothy , Jean Walter , Bigner Darell , Yan Hai , Waldman Todd
Published: April 2023

Supplementary Table 1 from Sample Type Bias in the Analysis of Cancer Genomes
Supplementary Figure 2 from Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation
Authors: Mohammad Helai P. , Cai Yi , McGarvey Kelly M. , Easwaran Hariharan , Van Neste Leander , Ohm Joyce E. , O'Hagan Heather M. , Baylin Stephen B.
Published: April 2023

Supplementary Figure 2 from Polycomb CBX7 Promotes Initiation of Heritable Repression of Genes Frequently Silenced with Cancer-Specific DNA Hypermethylation
Supplementary Figure 6 from Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL
Authors: Liu Li , Greger James , Shi Hong , Liu Yuan , Greshock Joel , Annan Roland , Halsey Wendy , Sathe Ganesh M. , Martin Anne-Marie , Gilmer Tona M.
Published: April 2023

Supplementary Figure 6 from Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL
Supplementary Table 3 from Follicle-Stimulating Hormone Peptide Can Facilitate Paclitaxel Nanoparticles to Target Ovarian Carcinoma In vivo
Authors: Zhang Xiao-yan , Chen Jun , Zheng Yu-fang , Gao Xiao-ling , Kang Yu , Liu Jia-chi , Cheng Ming-jun , Sun Hong , Xu Cong-jian
Published: April 2023

Supplementary Table 3 from Follicle-Stimulating Hormone Peptide Can Facilitate Paclitaxel Nanoparticles to Target Ovarian Carcinoma In vivo
Supplementary Figure 4 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Authors: Li Angela Y.J. , Boo Lee Ming , Wang Shih-Ya , Lin H. Helen , Wang Clay C.C. , Yen Yun , Chen Benjamin P.C. , Chen David J. , Ann David K.
Published: April 2023

Supplementary Figure 4 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Supplementary Figure 3 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Authors: Li Angela Y.J. , Boo Lee Ming , Wang Shih-Ya , Lin H. Helen , Wang Clay C.C. , Yen Yun , Chen Benjamin P.C. , Chen David J. , Ann David K.
Published: April 2023

Supplementary Figure 3 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Supplementary Figure 7 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Authors: Wada Satoshi , Yoshimura Kiyoshi , Hipkiss Edward L. , Harris Tim J. , Yen Hung-Rong , Goldberg Monica V. , Grosso Joseph F. , Getnet Derese , Demarzo Angelo M. , Netto George J. , Anders Robert , Pardoll Drew M. , Drake Charles G.
Published: April 2023

Supplementary Figure 7 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Supplementary Figure 8 from Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Authors: Jagani Zainab , Song Keli , Kutok Jeffery L. , Dewar M. Rajan , Melet Armelle , Santos Tanya , Grassian Alexandra , Ghaffari Saghi , Wu Catherine , Ren Ruibao , Rodin Heather Yeckes , Miller Kenneth , Khosravi-Far Roya
Published: April 2023

Supplementary Figure 8 from Proteasome Inhibition Causes Regression of Leukemia and Abrogates BCR-ABL–Induced Evasion of Apoptosis in Part through Regulation of Forkhead Tumor Suppressors
Supplementary Figure 5 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Authors: Wada Satoshi , Yoshimura Kiyoshi , Hipkiss Edward L. , Harris Tim J. , Yen Hung-Rong , Goldberg Monica V. , Grosso Joseph F. , Getnet Derese , Demarzo Angelo M. , Netto George J. , Anders Robert , Pardoll Drew M. , Drake Charles G.
Published: April 2023

Supplementary Figure 5 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Supplementary Figure 4 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Authors: Wada Satoshi , Yoshimura Kiyoshi , Hipkiss Edward L. , Harris Tim J. , Yen Hung-Rong , Goldberg Monica V. , Grosso Joseph F. , Getnet Derese , Demarzo Angelo M. , Netto George J. , Anders Robert , Pardoll Drew M. , Drake Charles G.
Published: April 2023

Supplementary Figure 4 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Supplementary Figure 3 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Authors: Wada Satoshi , Yoshimura Kiyoshi , Hipkiss Edward L. , Harris Tim J. , Yen Hung-Rong , Goldberg Monica V. , Grosso Joseph F. , Getnet Derese , Demarzo Angelo M. , Netto George J. , Anders Robert , Pardoll Drew M. , Drake Charles G.
Published: April 2023

Supplementary Figure 3 from Cyclophosphamide Augments Antitumor Immunity: Studies in an Autochthonous Prostate Cancer Model
Supplementary Figure 1 from Subcellular Localization of Cyclic AMP-Responsive Element Binding Protein-Regulated Transcription Coactivator 2 Provides a Link between Obesity and Breast Cancer in Postmenopausal Women
Authors: Brown Kristy A. , McInnes Kerry J. , Hunger Nicole I. , Oakhill Jonathan S. , Steinberg Gregory R. , Simpson Evan R.
Published: April 2023

Supplementary Figure 1 from Subcellular Localization of Cyclic AMP-Responsive Element Binding Protein-Regulated Transcription Coactivator 2 Provides a Link between Obesity and Breast Cancer in Postmenopausal Women
Supplementary Figures 1-3 from Loss of Retinal Cadherin Facilitates Mammary Tumor Progression and Metastasis
Authors: Agiostratidou Georgia , Li Maomi , Suyama Kimita , Badano Ines , Keren Rinat , Chung Su , Anzovino Amy , Hulit James , Qian Binzhi , Bouzahzah Boumediene , Eugenin Eliseo , Loudig Olivier , Phillips Greg R. , Locker Joseph , Hazan Rachel B.
Published: April 2023

Supplementary Figures 1-3 from Loss of Retinal Cadherin Facilitates Mammary Tumor Progression and Metastasis
Supplementary Movie 1 from Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
Authors: Di Vizio Dolores , Kim Jayoung , Hager Martin H. , Morello Matteo , Yang Wei , Lafargue Christopher J. , True Lawrence D. , Rubin Mark A. , Adam Rosalyn M. , Beroukhim Rameen , Demichelis Francesca , Freeman Michael R.
Published: April 2023

Supplementary Movie 1 from Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
Supplementary Movie 2 from The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55
Authors: van der Horst Armando , Khanna Kum Kum
Published: April 2023

Supplementary Movie 2 from The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55
Supplementary Movie 1 from The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55
Authors: van der Horst Armando , Khanna Kum Kum
Published: April 2023

Supplementary Movie 1 from The Peptidyl-Prolyl Isomerase Pin1 Regulates Cytokinesis through Cep55
Supplementary Figure 1 from RLIP76: A Target for Kidney Cancer Therapy
Authors: Singhal Sharad S. , Singhal Jyotsana , Yadav Sushma , Sahu Mukesh , Awasthi Yogesh C. , Awasthi Sanjay
Published: April 2023

Supplementary Figure 1 from RLIP76: A Target for Kidney Cancer Therapy
Supplementary Figure 4 from A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP
Authors: Meng Xiangjun , Leyva Mili L. , Jenny Marjorie , Gross Isabelle , Benosman Samir , Fricker Bastien , Harlepp Sébastien , Hébraud Pascal , Boos Anne , Wlosik Pauline , Bischoff Pierre , Sirlin Claude , Pfeffer Michel , Loeffler Jean-Philippe , Gaiddon Christian
Published: April 2023

Supplementary Figure 4 from A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP
Supplementary Figure 3 from A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP
Authors: Meng Xiangjun , Leyva Mili L. , Jenny Marjorie , Gross Isabelle , Benosman Samir , Fricker Bastien , Harlepp Sébastien , Hébraud Pascal , Boos Anne , Wlosik Pauline , Bischoff Pierre , Sirlin Claude , Pfeffer Michel , Loeffler Jean-Philippe , Gaiddon Christian
Published: April 2023

Supplementary Figure 3 from A Ruthenium-Containing Organometallic Compound Reduces Tumor Growth through Induction of the Endoplasmic Reticulum Stress Gene CHOP
Supplementary Tables 1-6 from Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition
Authors: Mirzoeva Olga K. , Das Debopriya , Heiser Laura M. , Bhattacharya Sanchita , Siwak Doris , Gendelman Rina , Bayani Nora , Wang Nicholas J. , Neve Richard M. , Guan Yinghui , Hu Zhi , Knight Zachary , Feiler Heidi S. , Gascard Philippe , Parvin Bahram , Spellman Paul T. , Shokat Kevan M. , Wyrobek Andrew J. , Bissell Mina J. , McCormick Frank , Kuo Wen-Lin , Mills Gordon B. , Gray Joe W. , Korn W. Michael
Published: April 2023

Supplementary Tables 1-6 from Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition
Supplementary Table 4 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Authors: Suzuki Hiromu , Takatsuka Shintaro , Akashi Hirofumi , Yamamoto Eiichiro , Nojima Masanori , Maruyama Reo , Kai Masahiro , Yamano Hiro-o , Sasaki Yasushi , Tokino Takashi , Shinomura Yasuhisa , Imai Kohzoh , Toyota Minoru
Published: April 2023

Supplementary Table 4 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Supplementary Figures 1-13 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Authors: Suzuki Hiromu , Takatsuka Shintaro , Akashi Hirofumi , Yamamoto Eiichiro , Nojima Masanori , Maruyama Reo , Kai Masahiro , Yamano Hiro-o , Sasaki Yasushi , Tokino Takashi , Shinomura Yasuhisa , Imai Kohzoh , Toyota Minoru
Published: April 2023

Supplementary Figures 1-13 from Genome-wide Profiling of Chromatin Signatures Reveals Epigenetic Regulation of MicroRNA Genes in Colorectal Cancer
Supplementary Table 1, Materials and Methods, Figure Legends 1-4 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Authors: Fischer Marcus , Yen Wan-Ching , Kapoun Ann M. , Wang Min , O'Young Gilbert , Lewicki John , Gurney Austin , Hoey Timothy
Published: April 2023

Supplementary Table 1, Materials and Methods, Figure Legends 1-4 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Supplementary Figures 1-16, Methods from A NOTCH3-Mediated Squamous Cell Differentiation Program Limits Expansion of EMT-Competent Cells That Express the ZEB Transcription Factors
Authors: Ohashi Shinya , Natsuizaka Mitsuteru , Naganuma Seiji , Kagawa Shingo , Kimura Sotai , Itoh Hiroshi , Kalman Ross A. , Nakagawa Momo , Darling Douglas S. , Basu Devraj , Gimotty Phyllis A. , Klein-Szanto Andres J. , Diehl J. Alan , Herlyn Meenhard , Nakagawa Hiroshi
Published: April 2023

PDF file - 347K
Supplementary Table 3 from Three-Dimensional Culture of Mouse Renal Carcinoma Cells in Agarose Macrobeads Selects for a Subpopulation of Cells with Cancer Stem Cell or Cancer Progenitor Properties
Authors: Smith Barry H. , Gazda Lawrence S. , Conn Bryan L. , Jain Kanti , Asina Shirin , Levine Daniel M. , Parker Thomas S. , Laramore Melissa A. , Martis Prithy C. , Vinerean Horatiu V. , David Eric M. , Qiu Suizhen , Cordon-Cardo Carlos , Hall Richard D. , Gordon Bruce R. , Diehl Carolyn H. , Stenzel Kurt H. , Rubin Albert L.
Published: April 2023

Supplementary Table 3 from Three-Dimensional Culture of Mouse Renal Carcinoma Cells in Agarose Macrobeads Selects for a Subpopulation of Cells with Cancer Stem Cell or Cancer Progenitor Properties
Supplementary Table 2 from Three-Dimensional Culture of Mouse Renal Carcinoma Cells in Agarose Macrobeads Selects for a Subpopulation of Cells with Cancer Stem Cell or Cancer Progenitor Properties
Authors: Smith Barry H. , Gazda Lawrence S. , Conn Bryan L. , Jain Kanti , Asina Shirin , Levine Daniel M. , Parker Thomas S. , Laramore Melissa A. , Martis Prithy C. , Vinerean Horatiu V. , David Eric M. , Qiu Suizhen , Cordon-Cardo Carlos , Hall Richard D. , Gordon Bruce R. , Diehl Carolyn H. , Stenzel Kurt H. , Rubin Albert L.
Published: April 2023

Supplementary Table 2 from Three-Dimensional Culture of Mouse Renal Carcinoma Cells in Agarose Macrobeads Selects for a Subpopulation of Cells with Cancer Stem Cell or Cancer Progenitor Properties
Supplementary Figure 2 from Natural Killer Cells Efficiently Reject Lymphoma Silenced for the Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing
Authors: Cifaldi Loredana , Lo Monaco Elisa , Forloni Matteo , Giorda Ezio , Lorenzi Silvia , Petrini Stefania , Tremante Elisa , Pende Daniela , Locatelli Franco , Giacomini Patrizio , Fruci Doriana
Published: April 2023

Supplementary Figure 2 from Natural Killer Cells Efficiently Reject Lymphoma Silenced for the Endoplasmic Reticulum Aminopeptidase Associated with Antigen Processing
Supplementary Figure 4 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Authors: Stauffer Jimmy K. , Scarzello Anthony J. , Andersen Jesper B. , De Kluyver Rachel L. , Back Timothy C. , Weiss Jonathan M. , Thorgeirsson Snorri S. , Wiltrout Robert H.
Published: April 2023

Supplementary Figure 4 from Coactivation of AKT and β-Catenin in Mice Rapidly Induces Formation of Lipogenic Liver Tumors
Supplementary Methods, Figure Legends 1-3 from Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
Authors: Kogo Ryunosuke , Shimamura Teppei , Mimori Koshi , Kawahara Kohichi , Imoto Seiya , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Suzuki Akira , Komune Shizuo , Miyano Satoru , Mori Masaki
Published: April 2023

PDF file - 104K
Supplementary Figure 3 from Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
Authors: Kogo Ryunosuke , Shimamura Teppei , Mimori Koshi , Kawahara Kohichi , Imoto Seiya , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Suzuki Akira , Komune Shizuo , Miyano Satoru , Mori Masaki
Published: April 2023

PDF file - 47K
Supplementary Figures 8-11 from Antioxidant Enzymes Mediate Survival of Breast Cancer Cells Deprived of Extracellular Matrix
Authors: Davison Calli A. , Durbin Sienna M. , Thau Matthew R. , Zellmer Victoria R. , Chapman Sarah E. , Diener Justin , Wathen Connor , Leevy W. Matthew , Schafer Zachary T.
Published: April 2023

Catalase elimination in MDA-MB-231 cells does not alter glucose uptake activity, Catalase elimination in MDA-MB-231cells does not alter cell proliferation, Catalase deficiency in MDA-MB-231 cells has no bearing on cell viability, Catalase deficiency in T47D cells does not affect glucose uptake.
Supplementary Figures 1-6 from Intravesical Delivery of Small Activating RNA Formulated into Lipid Nanoparticles Inhibits Orthotopic Bladder Tumor Growth
Authors: Kang Moo Rim , Yang Glen , Place Robert F. , Charisse Klaus , Epstein-Barash Hila , Manoharan Muthiah , Li Long-Cheng
Published: April 2023

PDF file - 687K, Figure S1. dsP21-322 triggers changes in cell morphology associated with growth inhibition. Figure S2. Anti-growth activities of LNP-dsP21-322-2'F and its non-formulated derivatives. Figure S3. Duplex stability in water and detection of nucleic acid background signal in urine. Figure S4. Uptake of LNP-formulated dsP21-322-2'F-FITC by bladder urothelium. Figure S5. GFP signature of orthotopic tumors in excised mouse bladders. Figure S6. Muscle invasive bladder tumor and metastatic bladder tumor in the kidney
Supplementary Figure Legends 1-5 from Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Authors: Kluza Jérome , Corazao-Rozas Paola , Touil Yasmine , Jendoubi Manel , Maire Cyril , Guerreschi Pierre , Jonneaux Aurélie , Ballot Caroline , Balayssac Stéphane , Valable Samuel , Corroyer-Dulmont Aurélien , Bernaudin Myriam , Malet-Martino Myriam , de Lassalle Elisabeth Martin , Maboudou Patrice , Formstecher Pierre , Polakowska Renata , Mortier Laurent , Marchetti Philippe
Published: April 2023

PDF file - 93K
Supplementary Methods from The Major Reverse Transcriptase–Incompetent Splice Variant of the Human Telomerase Protein Inhibits Telomerase Activity but Protects from Apoptosis
Authors: Listerman Imke , Sun Jie , Gazzaniga Francesca S. , Lukas Jason L. , Blackburn Elizabeth H.
Published: April 2023

PDF file - 56K
Supplementary Figure 1 from NADPH Oxidase NOX4 Supports Renal Tumorigenesis by Promoting the Expression and Nuclear Accumulation of HIF2α
Authors: Gregg Jennifer L. , Turner Robert M. , Chang Guimin , Joshi Disha , Zhan Ye , Chen Li , Maranchie Jodi K.
Published: April 2023

PDF file - 224K, Supplemental Figure 1. Quantitative RT-PCR (a) and semi-quantitative RT-PCR (b) for detection of Nox1 in 786-0, RCC4 or LNCaP prostate cancer cells using two published primer pairs(14, 17),. Error bar represents +/- SE.
Supplementary Figure 4 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: April 2023

PDF file - 3478KB, Knockdown of NDY1/KDM2B promotes differentiation of human mammary adenocarcinoma cell lines in culture.
Supplementary Figure S2 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: April 2023

Supplementary Figure S2. Treatment with ethyl pyruvate does not alter arginase or iNOS expression or induce MDSC apoptosis as compared to control-treated MDSC.
Supplementary Figure 6 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: April 2023

PDF file - 54K, Effect of gamma-secretase inhibitor on the NOTCH1 pathway genes and cell growth in HNSCC cells with NOTCH1 wildtype status. UPCI-SCC090 cells were growing on the media supplemented with 0.2 uM gamma-secretase inhibitor XXI (GSI-XXI) for up to 72 hours. The effect of GSI-XXI on the NOTCH1 targets HES1 and HEY1 is shown on the left for UPSI-SCC090 cell line.
Supplementary Table 1 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 116K, Correlation between expression of HIC1 and clinical pathological features in tissue microarrays.
Supplementary Figure 2 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: April 2023

PDF file - 169K, NOTCH pathway activation in HNSCC. A, Immunohistochemical analysis of NOTCH1, HES1 and HEY1 protein expression in HNSCC. Tissue microarray arrays with quadruplicates of samples from each of 56 HNSCC tumor and 11 non-tumor patients were stained with anti-NOTCH1, anti-HES1 or anti-HEY1 antibody, as described in methods. Top, the heat-map of immunohistochemical analysis for tissue microarray slides. Rows, genes; column, each individual sample. The average staining for four tissues was categorized to Strong (brown), Moderate (grey) or Weak/Negative (blue) staining. Samples are ranked by the pathology ID numbers in tumor (left) and normal (right) groups. Bottom: quantification of immunohistochemical data. The number and percentage of tumor (Tu) and normal (No) patient in strong, moderate and weak/negative category was quantified. P-values were calculated by comparing numeric scores in tumor vs normal sample by independent t test. The samples 57964, 58602, 22146, 5931, 26514 represent tumor samples X6, X7, X11, X28 and X34 from the original discovery cohort of 44 HNSCC tumors. B, Representative immunohistochemical results. The representative slides of positive or moderate staining are shown for tumors and compared to normal tissue. Bar, 100 um equivalent. Tumor (T) and normal (N) tissues on each sample are labeled. ID 22146 represented X11 samples, which were used both in array and in immunohistochemical analysis, where protein and RNA expression strongly correlate.
Supplementary Figure 4 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 77K, LCN2 does not affect MMP9 expression.
Supplementary Materials from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

PDF file 121K, Supplementary Methods and Figure Legends
Fig S2 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

PDF file 1425K, Confocal immunofluorescent imaging of Enox1 in zebrafish embryo heart, tail and chondrocytes
Supplementary Figure 2 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: April 2023

PDF file, 4242K, Induction of a constitutively active form of NFATc1 (NFATc1CA) promotes cancer cell migration.
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: April 2023

Supplemental Methods.
Supplementary Figure 7 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: April 2023

PDF file - 73K, BCL2l12 does not change the rate of proliferation and apoptosis.
Supplementary Figure 6 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 57KB, MLL4 Knockdown decreased UTX mRNA and protein levels, but UTX knockdown did not have any significant effect on MLL4 mRNA levels.
Supplementary Figure 3 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 21KB, UTX depletion did not affect the expression of Rb gene and other Rb pathway genes.
Supplementary Figure Legend from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: April 2023

PDF file - 47K
Supplementary Table 1 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: April 2023

XLSX file - 398K, Lists of genes differentially regulated by DHT in cyclin D1+/+ mice, DHT regulated genes in cyclin D1-/- mice and genes differentially regulated by cyclin D1.
Supplementary Figure 3 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: April 2023

PDF file - 219K, eQTL for CLPTM1L in adipose collected from 856 healthy female twins of the MuTHER resource.
Supplementary Figure 5 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: April 2023

PDF file - 131K, Endogenous cyclin D1 maintains prostate cancer stem cell population.
Supplementary Figure Legends from Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis
Authors: Yuzefovych Larysa V. , Kahn Andrea G. , Schuler Michele A. , Eide Lars , Arora Ritu , Wilson Glenn L. , Tan Ming , Rachek Lyudmila I.
Published: April 2023

Legend for Supplementary Figures S1-S4.
Supplementary Figures 1 - 8 from The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies
Authors: Vangamudi Bhavatarini , Paul Thomas A. , Shah Parantu K. , Kost-Alimova Maria , Nottebaum Lisa , Shi Xi , Zhan Yanai , Leo Elisabetta , Mahadeshwar Harshad S. , Protopopov Alexei , Futreal Andrew , Tieu Trang N. , Peoples Mike , Heffernan Timothy P. , Marszalek Joseph R. , Toniatti Carlo , Petrocchi Alessia , Verhelle Dominique , Owen Dafydd R. , Draetta Giulio , Jones Philip , Palmer Wylie S. , Sharma Shikhar , Andersen Jannik N.
Published: April 2023

Figure S1. Genomic analysis of SWI/SNF alterations in human cancer. Figure S2. SMARCA4-deficient lung cancer cells depend on SMARCA2 expression for growth. Figure S3. In-situ cell extraction assay for PFI-3 treatment. Figure S4. SMARCA2/4 bromodomain inhibitor does not alter growth of lung cancer cells. Figure S5. Analysis of SMARCA4 target gene expression and promoter occupancy following prolonged treatment with PFI-3. Figure S6. Pharmacological PFI-3 inhibitor studies in leukemia cells. Figure S7. Pharmacological EZH2 inhibitor studies. Figure S8. Genome-wide microarray analysis of SMARCA2 knockdown in A549 cells reconstituted with SMARCA4 cDNAs. Table S1: Survey of genomic lesions in SWI/SNF across different cancer types. Table S2: Sequence information of shRNA's and siRNA's used in the study. Table S3. BROMOScan (DiscoveRx) profiling of PFI-3 (at 2uM) against 32 bromodomains. Table S4. Definition of gene sets (i.e. SMARCA2 knockdown signatures) from SMARCA4 rescue experiments in A549 cells. Table S5. Summary of GSEA normalized enrichment scores (NES) and false discovery rate (FDR) for rescue experiment using ATP-Dead, BRD-Mut and vector control and compared to WT.
Supplementary Table S1 from Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
Authors: Mazzocca Antonio , Dituri Francesco , De Santis Flavia , Filannino Addolorata , Lopane Chiara , Betz Regina C. , Li Ying-Yi , Mukaida Naofumi , Winter Peter , Tortorella Cosimo , Giannelli Gianluigi , Sabbà Carlo
Published: April 2023

List of genes up-regulated in LPAR6 knocked down cells.
Supplementary Figure 2 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: April 2023

Representative images of CXCR2 staining in lung cancer specimens from the NCI-MD case control study.
Supplementary Table 3 from PI3K–mTORC2 but not PI3K–mTORC1 Regulates Transcription of HIF2A/EPAS1 and Vascularization in Neuroblastoma
Authors: Mohlin Sofie , Hamidian Arash , von Stedingk Kristoffer , Bridges Esther , Wigerup Caroline , Bexell Daniel , Påhlman Sven
Published: April 2023

Supplementary Table 3. siRNA oligos used for transfections.
Supplementary Tables S1-S2 from p21 Ablation in Liver Enhances DNA Damage, Cholestasis, and Carcinogenesis
Authors: Ehedego Haksier , Boekschoten Mark V. , Hu Wei , Doler Carina , Haybaeck Johannes , Gaβler Nikolaus , Müller Michael , Liedtke Christian , Trautwein Christian
Published: April 2023

Supplementary Tables S1-S2. Primer sequences used for qRT-PCR (S1); Primary and secondary antibodies used for Western blot analysis (S2).
Supplementary Figures S1-S3 and Suppl. Tables S1-S2 from AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor–Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment
Authors: Daurio Natalie A. , Tuttle Stephen W. , Worth Andrew J. , Song Ethan Y. , Davis Julianne M. , Snyder Nathaniel W. , Blair Ian A. , Koumenis Constantinos
Published: April 2023

Supplemental tables S1-S2: (S1) sequences of sgRNA for CRISPR-cas9 knock out cell lines. (S2) Fraction of oxygen consumption rate remaining after tamoxifen treatment at 30μM in cancer cell lines Supplemental Figures S1-S3: (S1) Oxygen consumption measurements of Tamoxifen, 4OH-Tamoxifen, and fulvestrant treatment, oxygen consumption of MCF7 cells treated with DMSO or fulvestrant plus tamoxifen and Immunoblot of ER expression with fulvestrant treatment, oxygen consumption measurements of mitochondria isolated from mouse liver treated with tamoxifen, clonogenic survival of MDA-231 cells treated with tamoxifen +/- Glucose and +/- methyl succinate, immunoblot of AMPK activation in the presence of glucose or 2DG and survival of BC cells treated with 2DG or 3BP. (S2) LC-MS/MS quantification of acyl-CoA species after tamoxifen treatment compared to control and BODPIY staining of MDA-231 cells treated with tamoxifen or DMSO control. (S3) Clonogenic survival and immunoblot of MCF7 shNT and shAMPK cells treated with 30μM tamoxifen, survival assays of MDA-231 cells with different AMPK status's following tamoxifen treatment, and autoradiograph film of 35S labeling in MDA-231 cells and MDA-231 crspAMPKα1.
Supplementary Figure 4 from eIF4E Threshold Levels Differ in Governing Normal and Neoplastic Expansion of Mammary Stem and Luminal Progenitor Cells
Authors: Avdulov Svetlana , Herrera Jeremy , Smith Karen , Peterson Mark , Gomez-Garcia Jose R. , Beadnell Thomas C. , Schwertfeger Kathryn L. , Benyumov Alexey O. , Manivel J. Carlos , Li Shunan , Bielinsky Anja-Katrin , Yee Douglas , Bitterman Peter B. , Polunovsky Vitaly A.
Published: April 2023

Supplementary Fig. S4. Over expressed eIF4E induces luminal subtype tumors.
Supplementary Figure S2 from miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src
Authors: Shi Xu-Bao , Ma Ai-Hong , Xue Lingru , Li Meimei , Nguyen Hao G. , Yang Joy C. , Tepper Clifford G. , Gandour-Edwards Regina , Evans Christopher P. , Kung Hsing-Jien , deVere White Ralph W.
Published: April 2023

Quantitative analysis of miR-125b levels in enzalutamide-resistant 22Rv1 (22Rv1-EnzR) cells.
Supplementary Figure S1 from miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src
Authors: Shi Xu-Bao , Ma Ai-Hong , Xue Lingru , Li Meimei , Nguyen Hao G. , Yang Joy C. , Tepper Clifford G. , Gandour-Edwards Regina , Evans Christopher P. , Kung Hsing-Jien , deVere White Ralph W.
Published: April 2023

The combination treatment with miR-124 and bicalutamide (Bic) significantly inhibited proliferation of C4-2B prostate cancer cells.
Supplemental Figure S1 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics
Authors: Crompton Joseph G. , Sukumar Madhusudhanan , Roychoudhuri Rahul , Clever David , Gros Alena , Eil Robert L. , Tran Eric , Hanada Ken-ichi , Yu Zhiya , Palmer Douglas C. , Kerkar Sid P. , Michalek Ryan D. , Upham Trevor , Leonardi Anthony , Acquavella Nicolas , Wang Ena , Marincola Francesco M. , Gattinoni Luca , Muranski Pawel , Sundrud Mark S. , Klebanoff Christopher A. , Rosenberg Steven A. , Fearon Douglas T. , Restifo Nicholas P.
Published: April 2023

Supplemental Figure S1. Clinical strategy to pharmacologically inhibit Akt during ex vivo expansion of tumor-infiltrating lymphocytes (TIL).
Supplementary Table S2 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: April 2023

Primer sequence information.
Supplementary Methods and References from An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer
Authors: Olow Aleksandra , Chen Zhongzhong , Niedner R. Hannes , Wolf Denise M. , Yau Christina , Pankov Aleksandr , Lee Evelyn Pei Rong , Brown-Swigart Lamorna , van ‘t Veer Laura J. , Coppé Jean-Philippe
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figures S1-S17 from An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer
Authors: Olow Aleksandra , Chen Zhongzhong , Niedner R. Hannes , Wolf Denise M. , Yau Christina , Pankov Aleksandr , Lee Evelyn Pei Rong , Brown-Swigart Lamorna , van ‘t Veer Laura J. , Coppé Jean-Philippe
Published: April 2023

Phospho-reactome curation workflow (S1); Proteins catalogued in PhosphoAtlas correspond to a unique subset of Protein-Protein Interactions, defined by their active, proven function in phospho-catalytic events (S2); Comparative connectivity between kinases, substrates and HPS's (S3); Most highly connected kinases and substrates (S4); Comparison between the number of enzyme - substrate pairs and the number of kinase - HPS - substrate connections across kinase subfamilies (S5); Disease ontology profile of AKT phospho-circuits (S6); Connectivity of AKT proteins to their upstream and downstream phospho-protein circuits (S7); Catalytic circuitry of AKT1 kinase: an expandable network of enzymatic interaction derived from mutation-prone phospho-target sites (S8); Identification of substrate proteins that are most affected by cancer-mutated peptides, and substrates that are not subject to alterations of their phospho-target sites (S9); Distribution and classification of SNP-altering target sites (S10); Heptameric target variants affecting phosphorylation sites mapped to COSMIC-curated tissue pathologies (S11); Identification of kinases impacted by cancer-mutations that alter their phosphorylatable target sites (S12); Map of the tumor kinome (S13, S14); Examples of kinase and substrate sub-networks, and the differential impact of tumor mutations on their phospho-signaling circuits (S15, S16, S17).
Supplementary Figures 1 through 9 from Activated Thyroid Hormone Promotes Differentiation and Chemotherapeutic Sensitization of Colorectal Cancer Stem Cells by Regulating Wnt and BMP4 Signaling
Authors: Catalano Veronica , Dentice Monica , Ambrosio Raffaele , Luongo Cristina , Carollo Rosachiara , Benfante Antonina , Todaro Matilde , Stassi Giorgio , Salvatore Domenico
Published: April 2023

Supplemental Material. Fig. S1: Summary of TRα and β, MCT8 and MCT10 expressions in the cell lines used in this study. Fig. S2: E-Cadherin and sucrose isomaltase expressions. Fig. S3: Flow cytometry profiles on freshly purified CRC cells. Fig. S4: Functional promoter studies in HEK293 cells treated or not with 30nM T3 in the presence of an empty vector or TRα expressing plasmid. Fig. S5: FACS analysis of cell cycle distribution of CR-CSCs untreated and treated with T3, FBS or FBS plus rT3. Fig. S6: p21 and p27 protein expression levels measured by western blot analysis in CR- CRC cells under different conditions. Fig. S7: Hes-1 expressions in cells knocked down for D3 (iD3). Fig. S8: Clustergrams of up and down-regulated Wnt Targets- and Pathways-related genes in CR-CSCs treated cells.Fig. S9: Representative H&E, CK20, Ki67, CD133 immunohistochemical analysis of cells treated with different THs.
Figure S9 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: April 2023

Effect of valproic (VA, 100 mg/kg, injection every second day for three weeks) on tumors formed by CW9019-Luc aRMS cells transplanted subcutaneously to athymic nude mice.
Cell line information from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response
Authors: Conery Andrew R. , Centore Richard C. , Spillane Kerry L. , Follmer Nicole E. , Bommi-Reddy Archana , Hatton Charlie , Bryant Barbara M. , Greninger Patricia , Amzallag Arnaud , Benes Cyril H. , Mertz Jennifer A. , Sims Robert J.
Published: April 2023

This file contains the source of all cell lines used for the work described in the manuscript as well as the methods by which cell lines are authenticated at the repositories.
Figure S5 from Heme Oxygenase-1 Controls an HDAC4-miR-206 Pathway of Oxidative Stress in Rhabdomyosarcoma
Authors: Ciesla Maciej , Marona Paulina , Kozakowska Magdalena , Jez Mateusz , Seczynska Marta , Loboda Agnieszka , Bukowska-Strakova Karolina , Szade Agata , Walawender Magdalena , Kusior Magdalena , Stepniewski Jacek , Szade Krzysztof , Krist Bart , Yagensky Oleksandr , Urbanik Aleksandra , Kazanowska Bernarda , Dulak Jozef , Jozkowicz Alicja
Published: April 2023

Effect of miR-206 on expression of differentiation markers in SMS-CTR eRMS (SMS) and CW9019 aRMS (CW) cell lines.
Supplementary table 1 from Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer
Authors: Regan Anderson Tarah M. , Ma Shi Hong , Raj Ganesh V. , Cidlowski John A. , Helle Taylor M. , Knutson Todd P. , Krutilina Raisa I. , Seagroves Tiffany N. , Lange Carol A.
Published: April 2023

Clinicopathological characteristics of TNBC explant tumors.