bluuebunny/crossref_metadata_2025 huggingface dataset:
Myocarditis Associated With COVID-19 Infection and Mrna Vaccination: A Review Article
Authors: Khan Arshan , K. Balaw Mohammad , Sattar Huma , Garg Yash , Sebastian Freny , Agyingi Chris , Fichadiya, Hardik , Haseeb Muhammad
Published: May 2022

Coronavirus disease 2019 (Covid-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Initially, COVID-19 was considered a respiratory illness, but later on, it was found out that this disease can affect many organ systems. Cardiovascular manifestations of this disease include myocarditis, heart failure, myocardial infarction, and thromboembolism. Myocarditis related to COVID-19 is thought to be due to the direct viral injury and host immune response. The cases of myocarditis after the COVID-19 mRNA vaccine have been reported in the literature as well. COVID-19 myocarditis can present as chest pain, shortness of breath, acute heart failure, arrhythmia, and possibly death. The initial workup should include an electrocardiogram (ECG) and troponins if myocarditis is suspected.
Further screening should be done if troponins are elevated, or the patient has ECG changes concerning myocardial damage. Noninvasive imaging that helps to diagnose COVID-19 myocarditis includes echocardiograms, computerized tomographic (CT) with contrast, and cardiac magnetic resonance imaging (CMR). An endomyocardial biopsy (EMB) can be performed if the diagnosis remains unclear. Initial treatment of COVID-19 myocarditis is mainly supportive, and intravenous immunoglobulin (IVIG) and corticosteroid may be effective, particularly in fulminant myocarditis. If the patient develops life-threatening arrhythmias or shock, advanced mechanical support is required. Early intervention is a critical factor in decreasing morbidity and mortality. Further research is needed to determine the efficacy of different treatment modalities, including IVIG and corticosteroids, in patients with COVID-19 myocarditis.
Insurgências estéticas e epistêmicas no Antropoceno: povos indígenas e a retomada da Mata Atlântica no sul da Bahia
Authors: Pereira Felipe Milanez , Souza Jurema Machado de A.
Published: May 2022

Este artigo apresenta uma perspectiva crítica do conceito do Antropoceno a partir da ecologia política, enfatizando as desigualdades na produção da situação catastrófica de emergência climática. A partir das epistemologias indígenas, discute-se a relação entre descolonização e saídas da crise. Tendo por base um projeto de pesquisa que uniu arte indígena e mapeamento de conflitos ambientais, tratamos do caso das retomadas indígenas no sul da Bahia, a reconstrução da Mata Atlântica a partir do trabalho de três artistas indígenas: Arissana Pataxó, Glicéria Tupinambá e Olinda Muniz Wanderley (Yawar Tupinambá)
Agradecimento a pareceristas do v. 18, n. 1, maio 2022
Authors: Os Editores
Published: May 2022

Agradecimentos
Kiedy potencjalnie nieśmieszny tekst zaczyna bawić? Kilka słów na temat wizualnych i werbalnych elementów memów internetowych
Authors: Lorenc Arkadiusz
Published: May 2022

The author of the present work focuses on showing that an internet meme (defined here as a graphic unit composed of a visual and verbal part) can be seen as an extension of traditional joke thanks to its visual part. A meme illustrates the content presented by its graphical part. A question if the visual part of a meme intensifies the humourous effect evoked by the text (verbal part of meme) will be analysed. If that is the case, to what extent it contributes. Also, it is shown that the verbal part of internet memes is not always humourous by nature. Hence, they not always can be called jokes. One of the aspects of the work are memes whose verbal part has a potential to evoke a humourous reaction (some verbal parts of memes analysed here are short jokes or one-liners, commonly accepted as funny, even if they weren’t presented with any graphic). However, some verbal parts of examined memes do contain an element conducive to humourous reaction but do not contain comprehensive information about the subject (what ist the grammatical subject of the sentence?) or other information that is necessary to put the text in some wider context (what the text is about?). Therefore, such texts would not be understood if presented without any additional visual element. The aim is to elicitate, how the visual part of a meme enables a complex understanding of its verbal part and, consiquently, makes the whole unit funny.
Hipertekstowe przypisy tłumacza – rekonesans
Authors: Sztorc Weronika
Published: May 2022

The article draws attention to the features characterizing some of contemporary literary translations, which can be connected with associative thinking, typical of the Internet, as well as with hypertext literature, based on a network of links between fragments of text. In the first part the technique of translator’s footnotes was discussed and some of translation scholars’ views on it were quoted. Then, the notion of associative thinking (consisting in moving between individual associations) was introduced. Next, characteristic features and examples of hypertext and proto-hypertext literature were presented, with special attention paid to Pale fire by Nabokov. In the latter, the focus is on footnotes and on the figure of the fictional editor (not so much the author). Finally, such translators’ footnotes were shown wherein the translator becomes visible. It may be in a form of a game with the reader, a dialogue with the author or a manifestation of their own presence in the text (or power over it). In some cases it seems that translators demand that their work be noticed and appreciated. They also compete with the authors for the readership’s attention and thus the reader has to move between fragments of the text, just like in the case of hyperlinks.
Raising the Profile of Agricultural Policy Research: National Engagement as a Pathway to Change
Authors: Cartmell Susanna , Mutimer Alice , Reeve Sophie , Frost Olivia
Published: May 2022

Throughout the Agricultural Policy Research in Africa (APRA) Programme of the Future Agricultures Consortium, country research teams were encouraged to engage at district and national levels. Towards the end of APRA, during 2021, each country team held final district and national level events in order to share research findings and highlight policy implications. This report evaluates APRA's national engagement to understand what went well, and to identify what improvements could have been made.
Accompanied Learning: Reflections on How ALRE Enhanced APRA’s Relevance and Effectiveness
Authors: Clark Louise
Published: May 2022

This case study explores the claim that the Accompanied Learning for Relevance and Effectiveness (ALRE) approach contributed to stronger relevance and effectiveness of the Agricultural Policy Research in Africa (APRA) research programme. This report outlines the accompanied learning function of the ALRE team and how this ‘critical friend’ role supported APRA research teams in defining and reviewing their impact pathways, identifying and refining emerging evidence ‘nuggets’, and considering how to frame these insights to gain traction with specific policy debates and discourse.
Assessment of Outreach and Engagement with Prospective Migrants by the Agencies Recruiting Labourers for Foreign Employment
Authors: Kharel Arjun , Shrestha Sudhir , Bhattarai Sadikshya , Oosterhoff Pauline , Snyder Karen
Published: May 2022

This study was conducted to identify the gaps in policies and practices of labour recruitment in Nepal and assess the outreach and engagement of major formal labour intermediaries, private recruitment agencies (PRAs) and pre-departure orientation training (PDOT) centres, with migrant workers for providing information on human trafficking prior to departure. The study used data from interviews with the management of 15 PRAs and 10 PDOT centres, along with a review of online materials published by the sampled PRAs and PDOT centres and existing publications on labour migration from Nepal.
The use of rigid gas permeable contact lens in managing severe anisometropia caused by monocular aphakia following retinal reattachment surgery and high myopia in a 13 year old girl: a case report
Authors: Rahayu Tri , Kalandra Kara Citra
Published: May 2022

Anisometropia if not treated accordingly may cause other issues especially in developing pediatric eyes. This case is a 13 year old female presented with chief complaint of headache and double vision upon wearing prescribed spectacles. Patient had history of high myopia on both eye, amblyopia and spontaneous rhegmatogenous retinal detachment on the left eye. Retinal reattachment and lensectomy surgery were conducted to correct the problem. The surgery was performed without intra ocular lens (IOL) implantation, which left her left eye become high hyperope due to aphakia. Patient was treated with RGP CLs. Final best visual acuity with EDTRS chart was 6/48 on both eyes. Patient reported subjective visual improvement, no headache or double vision.
Hyperbaric oxygen therapy for the treatment of a crush injury of the hand: a case report
Authors: Neto Pedro Henry , Ribeiro Zamara Brandão , Pinho Adriano Bastos , Almeida Carlos Henrique Rodrigues de , Maranhão Carlos Alberto de Albuquerque , Goncalves Joaquim da Cunha Campos
Published: May 2022

We describe a case of hyperbaric oxygen therapy (HBOt) as an adjunct to treatment of a crush injury to the hand. A 34-year-old male paramedic was involved in a motor vehicle accident and admitted for diagnosis and surgical treatment. He sustained a crush injury to his right hand and presented with significant muscle damage, including multiple fractures and dislocations, an avulsion injury of the flexor tendons, and amputation of the distal phalanx of the little finger. He underwent reconstructive surgery and received HBOt over the following days. In the following 2 months, he lost the distal and middle phalanges of the little finger and recovered hand function. Posttraumatic compartment syndrome responds well to HBOt, which reduces edema and contributes to angiogenesis, as well as promoting the cascade of healing events. High-energy trauma causes massive cell destruction, and the blood supply is usually not sufficient to meet the oxygen demands of viable tissues. Hyperbaric oxygenation by diffusion through interstitial and cellular fluids increases tissue oxygenation to levels sufficient for the host’s responses to injury to work and helps control the delayed inflammatory reaction. HBOt used as an adjunct to surgical treatment resulted in early healing and rehabilitation, accelerating functional recovery. The results suggest that adjunctive HBOt can be beneficial for the treatment of crush injuries of the hand, resulting in better functional outcomes and helping to avoid unnecessary amputations.
Research on the Protection of Basic Rights of the Vulnerable Groups in the Digital Divide
Authors: Wang Mengziwei
Published: May 2022

Recently, the Hubei face recognition case has aroused widespread concern in the society, and the protection of the basic rights of vulnerable groups in the Digital Divide has once again become a concern of the theoretical and practical circles. The Digital Divide is a phenomenon of social differentiation caused by the development of digital technology to a certain stage. The elderly and other vulnerable groups are limited by their own learning ability and adaptability, and have not been able to integrate into the smart society in time, and the government and enterprises have not paid enough attention to this kind of the additional difficulty of the disadvantaged groups in exercising their rights, so that social contradictions are gradually revealed. Establishing a reasonable social resource allocation mechanism and re-examining the law enforcement process of government departments will play an important role in protecting the basic rights of vulnerable groups in the Digital Divide.
Application of Nurse-Led Evidence-Based Nursing in Newly Diagnosed Type 2 Diabetes Patients
Authors: Jiang Lina , Tian Fenghua
Published: May 2022

Objective: To apply nurse-led evidence-based nursing to newly diagnosed patients with type 2 diabetes, and to analyze its effect.Methods: Convenience sampling method was adopted, and 42 patients with initial diagnosis of T2DM who were admitted to the endocrinology department of a tertiary hospital in Chifeng City from September 2021 to February 2022 were included in the study. Grouping was done by random number table method, and finally 21 cases were included in each of the experimental group and the control group. The patients in the control group received routine nursing in the endocrinology department, and the patients in the experimental group received evidence-based nursing led by nurses on this basis. The glucose metabolism indexes and self-management behaviors of the two groups of patients were analyzed.Results: After routine nursing and nurse-led evidence-based nursing for newly diagnosed patients with type 2 diabetes, the blood sugar control of the experimental group was significantly better than that of the control group, and the difference was statistically significant (P<0.05). The behavior was better than that of the control group, and the difference was statistically significant (P<0.05). The nursing satisfaction of the patients in the experimental group was higher than that of the control group, and the difference was statistically significant (P<0.05).Conclusion: In view of the particularity of the newly diagnosed type 2 diabetes patients, in the process of nursing them, the nurse-led evidence-based nursing can effectively control the blood sugar level and improve the patients' self-esteem based on summarizing the best evidence. Management ability and nursing satisfaction are worthy of promotion and application in clinical practice.
The Effect of Teachers’ Questioning Upon Junior High School Students’ English Classroom Activity: Taking W School for Example
Authors: Lou Yeying
Published: May 2022

Taking W Middle School for example, this paper is aimed to explore the effect of teachers’ questioning upon junior high school students’ English classroom activity. Classroom observation, questionnaire and face-to-face interview are employed as the research method. The results show that classroom questioning can be divided into display questions and referential questions in English teaching. Besides, the easier questions are, the more active students are, so it’s interesting to find out all the students interviewed by the writer said they prefer to answer questions of appropriate difficulty. In addition, most students prefer open questions according to the data from questionnaires. What’s more, there are many factors leading to low activity and negative classroom atmosphere is the main factor.
THE COVID ROLLERCOASTER: Multiple and Multi-dimensional Transitions of Healthcare Graduates
Authors:   University of Dundee, Tooman Tricia , Al-Yaseen Waraf , Herd Damon , Ding Clio , Corrales Maria , Teo Lewen Jaina
Published: May 2022

In this study, we explored the ongoing multiple and multi-dimensional transitions experienced by medicine, nursing and dentistry students due to graduate in summer 2020. Some graduated early to join the NHS workforce and others had their graduation deferred for a year due to lack of clinical experience. We explored the expectations and realities of their transition experiences; their perceptions of the impact of their transitions on them, their wellbeing, and on their significant others. This longitudinal study helped understand each individual’s adaptations to multiple concurrent changes over time. The cross-sectional data revealed trends and patterns for each group of graduates. This comic anthology presents the interpretations of interview data from doctor, nurse, and dentist graduates. The five comics present both individual and composite narratives of different participants. The visualisation of the data through comics was valuable to portray the wider context of COVID-19, and participants’ related transition experiences and emotions.
Property Variation of Extruded Mg-Gd Alloys by Mn Addition and Processing
Authors: Wiese Björn , Harmuth Jochen , Willumeit-Römer Regine , Bohlen Jan
Published: May 2022

The manufacturing parameters influence the properties of thermo-mechanically processed met-als such as Mg alloys. This paper presents how the mechanical properties, the microstructure and the degradation rate of extruded Mn-containing Mg-Gd-alloys can be modified. Gd as repre-sented REE-element is particularly interesting due to the influence on the texture development in Mg and therefore studied as a base alloy system. The contents of Gd were investigated be-tween 2 to 9 wt.% with Mn-addition of 0.5 and 1.0 wt.%. The grain sizes and the corresponding textures were modified by the extrusion parameters and the alloy content. It was shown that modification by Mn can decrease the grain size, but increase the degree of recrystallization and decrease the degradation rate in the biological medium compared to the binary Mg-Gd system from previous studies. The results suggest that the binary Mg-Gd system can be produced more efficiently by adding Mn and that the resulting properties are more robust.
Electron-Phonon Coupling and Nonthermal Effects in Gold Nano-Objects at High Electronic Temperatures
Authors: Medvedev Nikita , Milov Igor
Published: May 2022

Laser irradiation of metals is widely used in research and applications. In this work, we study how the material geometry affects electron-phonon coupling in nano-sized gold samples: an ultrathin layer, nano-rod, and two types of gold nanoparticles: cubic and octahedral. We use the combined tight-binding molecular dynamics Boltzmann collision integral method implemented within XTANT-3 code to evaluate the coupling parameter in irradiation targets at high electronic temperatures (up to Te~20,000 K). Our results show that the electron-phonon coupling in all objects with the same fcc atomic structure (bulk, layer, rod, cubic and octahedral nanoparticles) is nearly identical at electronic temperatures above Te~7000 K, independently of geometry and dimensionality. At low electronic temperatures, reducing dimensionality reduces the coupling parameter. Additionally, nano-objects under ultrafast energy deposition experience nonthermal damage due to expansion caused by electronic pressure, in contrast to bulk metal. Nano-object ultrafast expansion leads to ablation/emission of atoms, and disorder inside of the remaining parts. These nonthermal atomic expansion and melting are significantly faster than electron-phonon coupling, forming a dominant effect in nano-sized gold.
TIME RISK ANALYSIS OF IMPLEMENTATION SELF-MANAGED COMMUNITY PROJECT IN KALIANYAR - BANGIL VILLAGE
Authors: Cahyono Luqman , Apriani Mirna , Trisna Nugraha Anggara , Prasetyo Utomo Agung
Published: May 2022

Self-managed project through of KOTAKU (Kota Tanpa Kumuh) program managed by Lembaga Keswadayaan Masyarakat Abdi Karya Amanah Kalianyar - Bangil Village received around 1 billion funds from Direktorat Jenderal Cipta Karya Kementrian Pekerjaan Umum Dan Perumahan Rakyat. The implementation of self-managed projects is carried out entirely by the community with less knowledge regarding building construction. The research objective is to identify and analyze time risks in implementing community self-managed projects. The data analysis method used is literature study, observation, average analysis, risk analysis and risk matrix preparation. The results of the analysis show that there are 20 risk variables with the highest ranking being low labor productivity where the measurement scale is likely to occur >60–80% and the risk impact on time is >7-30 days from the duration of the project, then the risk response decision "Avoidance" risk must be avoided.
EPANET MODEL CLEAN WATER NETWORK CALLIBRATION USING MODIFIED ROUGHNESS C NUMBER HAZEN WILLIAM METHOD
Authors: Limbong Benson , Suripin Suripin , Sudarnoutaomo Sudarnoutaomo
Published: May 2022

The Epanet model in clean water pipelines is intended for time efficiency in calculating hydraulic behaviour. Calibration of the water pipe network is to compare the simulation results of the model to actual field observations and to see that the model that has been made is truly valid and reliable as a tool to determine the hydraulic behaviour of the network system when a change input into the system is given (e.g. the addition of pipelines and number of customer tapping debits). The pipe roughness coefficient (C) is a number that indicates the amount of energy loss due to friction between the flowing fluid and the pipe wall. The increasing age of the pipe will cause the pipe wall roughness to increase, and the energy loss will be even more significant. This research aims to calibrate the pipe network model by adjusting the C value of the actual pipe roughness coefficient according to the installed age. An initial simulation model was carried out by entering the standard pipe C value in the Hazen Williams energy loss equation in the Epanet link/pipe properties. Then a simulation is carried out by modifying the value of C according to the pipe's service life. For 600 mm steel pipe, change the C value from 150 to 87 (pipe age >30 years), HDPE 315 mm pipe changes in C value from 140 to 100 (pipe age >10 years) and 25-50 mm PVC pipe from 140 to 100 (pipe age >10 years). From the simulation results of the Epanet model-field observations, the average compressive height was obtained for five observation nodes.of 2 tails was performed paired sample test the pressure height value of the model-observation. Before modifying the value of C, the paired mean difference test results showed a significant difference between the simulation results of the model on field observations with a model significance value of 0.004, which means <0.005. There is a considerable difference between the simulations and observations, and the model is considered invalid. However, after modifying the value of C according to the actual age of the pipe, a paired sample test T average value of the compression model-observation was 0.098 > 0.005), which means that there is no significant difference between the simulation and observation. This means that the model made is quite valid. Product moment correlation between the model simulation height - field observations, the value of R = 0.967, the relationship is robust between the two results.
Growth assessments of starry stonewort (Nitellopsis obtusa) in various substrate types for large-scale cultivation studies
Authors: Pokrzywinski Kaytee , Grasso Christopher , Volk Kaitlin , Sartain Bradley , Fernando Briana
Published: May 2022

The purpose of this study was to compare multiple substrate types to optimize cultivation conditions for the invasive macroalga Nitellopsis obtusa (Desv. in Loisel.) J. Groves, commonly known as starry stonewort. Large-scale cultivation will allow for tiered approaches to management evaluation research while minimizing the influence of confounding variables.
Entre insensatos y locos. José Ignacio Moreno: filosofía política y debate en la Independencia del Perú (1822)
Authors: Rivera Víctor Samuel
Published: May 2022

En el contexto del Bicentenario de la Independencia del Perú, este texto busca recuperar para la memoria la obra de José Ignacio Moreno, uno de los gestores del proceso constituyente que atravesó el Perú desde el Protectorado de José de San Martín. De manera particular vamos a enfocarnos en su filosofía política, que ha sido peculiarmente desatendida en la historiografía relativa a la Independencia y que surge, justamente, a la luz del proceso de transición entre el antiguo régimen peruano y la consolidación de la república. De hecho, un primer objetivo de este trabajo es mostrar a Moreno como parte del proceso de gestión constitucional que dio lugar a la república peruana en calidad de interlocutor en la polémica pública. Para este propósito vamos a centrar el interés en su libro Cartas peruanas (1826), un texto de metafísica política escrito en el fragor constitucional del periodo de su presencia en el ambiente político y académico del Perú en los inicios de su vida independiente.
La etnicidad en el Perú y su naturaleza multidimensional: una propuesta de medición
Authors: Campos Briceño Guiliana Rocío , Condor Iturrizaga Ronny Martin
Published: May 2022

La etnicidad es un concepto complejo de definir en las ciencias sociales. Esta complejidad se debe a que diversos autores reconocen a la etnicidad como un conjunto de características raciales, sociales y culturales que comparten un grupo de personas. Debido a ello, la naturaleza misma de la etnicidad es multidimensional. El presente documento tiene como objetivo construir un índice que mida la multidimensionalidad de la etnicidad usando datos de la encuesta de hogares de Perú en 2007 y 2017. El método usado para construcción del índice es el análisis de componentes principales (ACP). Además, se presenta un análisis correlacional del índice propuesto con la incidencia de la pobreza, variables educativas y laborales. Entre los resultados encontrados, tenemos que hay una mayor intensidad étnica en la población en situación de pobreza, en condición de analfabetismo y con menores niveles educativos, así como en la población autoempleada.
Dynamic response analysis of high-speed maglev train
Authors: Liu Meng-juan , Wu Han , Zeng Xiao-Hui , Yin Bo , Hao Zhan-zhou
Published: May 2022

Maglev train is suspended through the surrounding track, which overcomesmany disadvantages caused by the direct contact between the wheel and rail oftraditional vehicles, such as excessive friction. It has the advantages of high speed,comfortable riding, less maintenance, strong climbing ability, and so on. However,when the train is running at high speed, it will be subjected to a strong unsteadyaerodynamic load. The violent disturbance of aerodynamic load will inevitably lead tothe corresponding feedback of electromagnetic force and the change of the suspensiongap, which will affect the stability and safety of the train.
The performance of pretreatment MR-based radiomics in Recombinant human endostatin plus concurrent chemoradiotherapy response prediction in nasopharyngeal carcinoma: A primary study
Authors: Huang Lixuan , Yang Zongxiang , Kang Min , Ren Hao , Jiang Muliang , Tang Cheng , Hu Yao , Shen Mingjun , Lin Huashan , Long Liling
Published: May 2022

Purpose
To investigate the capability of an MRI radiomics model based on pre-treatment texture features in predicting the short term efficacy of RHES + concurrent chemoradiotherapy (CCRT) for NPC.
Methods
We retrospectively enrolled 65 patients newly diagnosed as having NPC and treated with RHES + CCRT. 144 texture features were extracted from the MRI before RHES + CCRT treatment of all the NPC patients. The maximum relevance minimum redundancy (mRMR) method was used to remove redundant, irrelevant texture features, and calculate the Rad score of the primary tumor. Multivariable logistic regression was used to select the most predictive features subset, and prediction models were constructed, which included radiomics models, clinics models, and combined models. The performance of the three models in predicting the early response of RHES + CCRT for NPC was explored.
Results
The diagnostic efficiency of combined model and radiomics model in distinguishing between the effective and the ineffective groups of patients was found to be moderate. The area under the curve (AUC) of the combined model and radiomics model was 0.74 (95% CI: 0.62–0.86) and 0.71 (95% CI: 0.58–0.84), respectively, with both being higher than the AUC of the clinics model (0.63, 95% CI: 0.49–0.78). Compared with the radiomics model, the combined model showed marginally improved diagnostic performance in predicting RHES + CCRT treatment response. The accuracy of combined model and radiomics model for RHES + CCRT response assessment in NPC were higher than those of the clinics model (0.723, 0.723 vs. 0.677).
Conclusion
The pretreatment MRI based radiomics can predict RHES + CCRT response in patients with NPC with a better accuracy than the clinics model.
Polysulfone nanocomposite membranes containing nanostructured TiO2, SiO2 and 3-Aminopropyltriethoxysilane (APTES) modified nano-TiO2 and nano-SiO2 nanocomposites : Fabrication, characterization and removal of cadmium (Cd2+) ions from aqueous solution
Authors: Pereira Valeen Rashmi , Isloor Arun M. , Kumar Mithun , Ismail Ahmad Fauzi
Published: May 2022

Cadmium pollution in drinking water from industrial wastewater is a global environmental concern that poses a significant health hazards for living organisms in the ecosystem. Hence, it was planned to prepare by phase inversion method to remove cadmium (Cd2+) ions from aqueous solution. The nano-TiO2 and nano-SiO2 were chemically modified with –NH2 groups on the surface, which was achieved using 3-Aminopropyltriethoxysilane (APTES). The constant concentration of 1.0 wt.% of nano-TiO2, nano-SiO2, aminated nano-TiO2, and aminated nano-SiO2 was maintained in the modified membranes. The Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), water uptake, contact angle, antifouling capabilities and heavy metal ion removal studies were performed for all fabricated membranes. The effect of amine-functionalized nano-TiO2 and nano-SiO2, on the membrane performance, was studied with reference to the membrane morphology, topography and membrane hydrophilic properties. By introducing aminated nano-TiO2 and nano-SiO2 in to a virgin PSf membrane, the membrane's permeability, hydrophilicity, and antifouling ability were significantly improved. The membranes were also screened for their possible application for cadmium rejection, which showed a maximum rejection of 75.6% for Cd2+ metal ions. This membrane material is highly potential for effective removing of cadmium heavy metal present in aqueous body.
Laparoscopic Sleeve Gastroplasty in a patient with cirrhosis and diabetes: a case report
Authors: Scheibe Christian Lamar , Valadão José Aparecido , de Oliveira Caio Márcio Barros , Moura Ed Carlos Rey , Campelo Giuliano Peixoto , de Lima Roclides Castro , Pinto Luis Eduardo Veras , Alencar Bruno Ribeiro , de Oliveira Eduardo José Silva Gomes , Leal Plinio da Cunha
Published: May 2022

Introduction: The percentage of obese people is growing at a rapid pace, increasing the number of patients the number of patients undergoing bariatric surgery. It is known that non-alcoholic fatty liver disease is known to progress to cirrhosis. Currently there is no consensus about the surgical technique indicated for the cirrhotic patient who will cirrhotic patient who will undergo bariatric surgery. Gastric bypass surgery in Y is a classic technique widely used. However, when compared with the gastric Sleeve, the by-pass has disadvantages such as more difficult technique, longer surgical time, and more postoperative postoperative and nutritional complications. Case Presentation: Obese, hypertensive, diabetic patient who had his RYGB suspended after the intraoperative finding of cirrhosis. He was subsequently classified as CHILD A and underwent vertical gastrectomy. After one year of follow-up he presented good weight loss, good control of hypertension, diabetes arterial hypertension, diabetes, and improved liver function and lipid profile. Conclusion: It is understood, that gastric Sleeve may soon become the surgery of choice for cirrhotic patients CHILD A.
Recovery of Critical Metals from Leach Solution of Electronic Waste using Magnetite Electrospun Carbon Nanofibers Composite
Authors: Iqbal Aamir , Jan M. Rasul , Shah Jasmin , Rashid Bahroz
Published: May 2022

Scarcity in mining and geo-political direction diverts attention toward critical metals recycling. Gallium (Ga), Indium (In) and Germanium (Ge) are among the critical metals consume approximately 80 percent of its world mining in innovative production of electrical and electronic equipment. The fast obsolescing rate generate large amount of electronic waste, which is now seen as secondary reservoir for critical metals. These metal resources need to be dealt with effective recycling capabilities. Based on solid phase extraction, magnetic nano-hydrometallurgy is opening a new area of metallic contents recovery in conventional hydrometallurgy. In the present work, polyacrylonitrile (PAN) based electrospun nanofibers were synthesized and carbonized at 800°C in the inert environment. After surface oxidation, carbon nanofibers were decorated with magnetite particles through co-precipitation. The saturation magnetization value (Ms = 23.6emu/g) confirm high loading of magnetite particles. The selected critical metal ions are freely present in aqueous solution at pH 1 to 3, thus highest removal efficiency was observed at pH 2. Pseudo second order kinetics confirm the chemical/charges interaction between sorbent and sorbate ions. Maximum sorption capacity calculated through Langmuir isotherm was 226, 191, 171 mg/g for Ge(IV), Ga(III) and In(III) metal ions, respectively. The RL value (0 < RL>1) indicate favourable sorption process. The sorbed target metal ions were collectively eluted using 1mol/L hydrochloric acid. The preconcentration factor was calculated 1080 for Ge(IV) and In(III) while 1260 for Ga(III). The method was validated with 5µg/mL spiked multi-element standards and applied to multiple acid leached electronic waste samples like PCBs, waste LCD panels and solar panels etc. Recoveries in the range of 96.2% for Ga(III), 95.6% for In(III) and 97.4% for Ge(IV) in the presence of diverse ions indicate the suitability of the proposed method for target metal ions even in complex matrix.
Impact of different numbers of milk test-day records during lactation on the reliability of estimated breeding values
Authors: Feltes Giovani Luis , Michelotti Vanessa Tomazetti , Oliveira Mauricio Morgado , Breda Fernanda Cristina , Rorato Paulo Roberto Nogara , Negri Renata , Padilha Alessandro Haiduck , Cobuci Jaime Araújo
Published: May 2022

The objective of this study was to evaluate the impact of the reduction in the number of test-day records per lactation on genetic parameters of test-day milk yield (TDMY) and the reliability of estimated breeding values for 305-day milk yield in Holstein cattle. Through the random elimination of milk test-days over the lactation period, seven subpopulations were formed, which differed in number of test-day records/lactation/cow, so that all cows in each subpopulation necessarily contained four to ten records per lactation. Estimates of genetic parameters and breeding values were performed using the animal model of random regression and adjustment of the Legendre polynomial (fourth order). When comparing sires with the same number of daughters, greater reliability was found in the subpopulations with the highest number of milk test-day records/lactation/cow. It was also found that the elimination of at least one test-day affected the reliability of estimated breeding value for 305-day milk yield in the sires, regardless of the class of number of daughters/sires. When selecting the 5% best sires and 20% best cows, the lowest order correlations were observed between the population with 10 test-day records/lactation (complete lactation) and the other subpopulations with incomplete lactations (4, 5, 6, 7, 8, 9 test-day records/lactation). The reduction in the number of milk test-day records per lactation interferes in the reliability of the estimated breeding value for sires and cows, negatively impacting the precision of selecting genetically superior animals.
Solution Processed CZTS Thin Films and its Simulation Study for Solar Cell Applications with ZnTe as the Buffer Layer
Authors: Singh Amanpal , Prakash Bhanu , Meena Arti , Saini Yogesh Kumar , Mahich Sanju , Kumari Sarita , Tripathi Chander Shekhar Pati , Choudhary Banwari Lal
Published: May 2022

The use of ZnTe as the buffer layer in the Cu2ZnSnS4 (CZTS) based solar cells showed the improvement in overall efficiency. It may also reduce the overall cost of these cells as both the layers (absorbing and buffer) are having eco-friendly and earth abundant constitutes. The sol-gel spin coating method is used for the deposition of CZTS thin films on the corning glass substrates. The X-ray diffraction studies showed the peaks corresponding to (112), (200), (220) and (312) planes which confirmed the formation of essential kesterite phase. The optical band gap of the deposited films was found around 1.9 eV by UV-visible spectrophotometer. The optimum thickness of the absorber layer was investigated based on the performance of ZnO:Al/ZnO/ZnTe/CZTS/Mo cell structure by using AMPS-1D simulation tool, while the tool was moulded by the investigated data from the sol-gel deposited CZTS thin films. The efficiency of solar cell was found to be increased till 22.64% with increment in the thickness of absorber buffer layer up to 2500 nm and beyond this it starts to decrease. In addition to this, it was also analysed that the current density is improved with operating temperature as it is one of the requirements in the high solar radiation areas where the temperature rise more than 50ᵒC in summer.
Hybrid cryptosystem based on deterministic phase masks in Fresnel domain and Yang-Gu mixture amplitude-phase retrieval algorithm
Authors: Tobria Archana , Singh Phool
Published: May 2022

In this paper, an encryption scheme based on double deterministic phase encoding and Yang-Gu mixture amplitude-phase retrieval algorithm is proposed. The deterministic phase masks are constructed using chaotic logistic and cubic maps. Firstly, an input image is encoded with double deterministic phase masks in Fresnel domain. The phase truncated part of the resulting image is used as an input to the Yang-Gu mixture amplitude-phase retrieval algorithm in the Fourier domain. The encrypted image is obtained by one-way binary modulation is real-valued which makes it more convenient for storage and transmission. The proposed cryptosystem is termed as hybrid as it combines a symmetric and an asymmetric scheme. The validation of the proposed cryptosystem is performed by numerical simulations on grayscale images of Man, DICOM, and a binary image. The proposed scheme is investigated for its robustness through statistical analysis using histogram and correlation plots. The scheme is also tested for its resistance against occlusion, noise, and cryptographic attacks. The proposed cryptosystem is found to be highly sensitive to its private key and the Fresnel parameters.
NSMCE2, a Novel Super-Enhancer-Regulated Gene, is Linked to Poor Prognosis and Therapy Resistance in Breast Cancer
Authors: Benedetto Carolina Di , Oh Justin , Choudhery Zainab , Shi Weiquan , Valdes Gilmer , Betancur Paola
Published: May 2022

Background
Despite today’s advances in the treatment of cancer, breast cancer-related mortality remains high, in part due to the lack of effective targeted therapies against breast tumor types that do not respond to standard treatments. Therefore, identifying additional breast cancer molecular targets is urgently needed. Super-enhancers are large regions of open chromatin involved in the overactivation of oncogenes. Thus, inhibition of super-enhancers has become a focus in clinical trials for its therapeutic potential. Here, we aimed to identify novel super-enhancer dysregulated genes highly associated with breast cancer patients’ poor prognosis and negative response to treatment.
Methods
Using existing datasets containing super-enhancer-associated genes identified in breast tumors and public databases comprising genomic and clinical information for breast cancer patients, we investigated whether highly expressed super-enhancer-associated genes correlate to breast cancer patients’ poor prognosis and to patients’ poor response to therapy. Our computational findings were experimentally confirmed in breast cancer cells by pharmacological SE disruption and gene silencing techniques.
Results
We bioinformatically identified two novel super-enhancer-associated genes – NSMCE2 and MAL2 – highly upregulated in breast tumors, for which high RNA levels significantly and specifically correlate with breast cancer patients’ poor prognosis. Through in-vitro pharmacological super-enhancer disruption assays, we confirmed that super-enhancers upregulate NSMCE2 and MAL2 transcriptionally, and, through bioinformatics, we found that high levels of NSMCE2 strongly associate with patients’ poor response to chemotherapy, especially for patients diagnosed with aggressive triple negative and HER2 positive tumor types. Finally, we showed that decreasing NSMCE2 gene expression by super-enhancer blockade or by directly silencing it increases breast cancer cells’ sensitivity to chemotherapy treatment.
Conclusions
Our results indicate that moderating the transcript levels of NSMCE2 could improve patients’ response to standard chemotherapy consequently improving disease outcome. Our approach offers a new avenue to identify a signature of tumor specific genes that are not frequently mutated but dysregulated by super-enhancers. As a result, this strategy can lead to the discovery of potential and novel pharmacological targets for improving targeted therapy and the treatment of breast cancer.
Usefulness of three protein signatures (Mastocheck) for follow-up after breast cancer surgery
Authors: Kim YUMI , Noh Dong-Young , Lim Changjin , Kim Hong-Kyu , Kim Sungsoo , Ahn Kyung-guen
Published: May 2022

Purpose: This study aimed to evaluate whether the three protein markers that we had developed previously for early breast cancer diagnosis, are useful for postoperative follow-up. Methods: Of 111 patients with breast cancer that were prospectively enrolled and underwent blood tests before, 8-weeks, 6-months, or 1-year after surgery, 53 underwent serial tests preoperatively to 1-year postoperatively. Protein biomarker changes were analyzed before and after surgery. Moreover, 145 patients who underwent surgery >1 year previously, were prospectively enrolled into the recurrence and non-recurrence (no evidence of disease; NED) groups. Using traditional and artificial intelligence analysis methods, we determined whether the biomarkers could identify disease presence or absence, and evaluated whether significant correlation occurred in biomarker changes. Results: Of the 111 included patients, 105 and 53 were followed-up for 8 weeks and 6 months to 1 year after surgery, respectively. Preoperatively, biomarker diagnostic sensitivity was 73.0%; 8-weeks and 6-months to 1-year after surgery, normalized blood biomarker level occurred in 67.6% and 86.8% of patients, respectively. Among 53 patients with serial tests, preoperative test sensitivity was 73.6%, which normalized after 6 month in 86.8%. Greater than 1-year after surgery, 38/63 patients with recurrence developed cancer, and 66/81 NED patients were cancer-free (62.5% sensitivity; 81.5% specificity). The upgraded version of biomarker analysis confirmed a further improved performance (with recurrence, 82.5% sensitivity; with NED, 87.7% specificity). Conclusions: Blood protein signatures (Mastocheck) developed for early breast cancer diagnosis normalized over time postoperatively, and could be used as a biological monitoring test after breast cancer surgery.
Patient-controlled intravenous analgesia with opioids after thoracoscopic lung surgery: a randomized clinical trial
Authors: Yu Hong , Tian Wei , Xu Zhao , Jiang Rongjuan , Jin Liang , Mao Wenjie , Chen Ying , Yu Hai
Published: May 2022

Background
Opioids remain the mainstream therapy for post-surgical pain. The choice of opioids administered by patient-controlled intravenous analgesia (PCIA) for thoracoscopic lung surgery is unclear. This study compared 3 opioid analgesics for achieving satisfactory analgesia with minimal emesis (SAME).
Methods
This randomized clinical trial enrolled patients scheduled for thoracoscopic lung surgery randomized to receive 1 of 3 opioids for PCIA: oxycodone (group O), hydromorphone (group H), and sufentanil (group S). The primary outcome was the proportion of subjects achieving SAME, i.e., no-to-mild pain (pain score < 4/10) with minimal nausea/vomiting (PONV score < 2/4) when coughing during the pulmonary rehabilitation exercise in the first 3 postoperative days.
Results
Of 555 enrolled patients, 184 patients in group O, 186 in group H and 184 in group S were included in the final analysis. The primary outcome of SAME was significantly different among group O, H and S (41.3% vs 40.3% vs 29.9%, P = 0.043), but no difference was observed between pairwise group comparisons. Patients in groups O and H had lower pain scores when coughing on the second day after surgery than those in group S, both with mean differences of 1 (3(3,4) and 3(3,4) vs 4(3,4), P = 0.009 and 0.039, respectively). The PONV scores were comparable between three groups (P > 0.05). There were no differences in other opioid-related side effects, patient satisfaction score, and QoR-15 score among three groups.
Conclusions
Given clinically relevant benefits detected, PCIA with oxycodone or hydromorphone is superior to sufentanil for achieving SAME as a supplement to multimodal analgesia in patients undergoing thoracoscopic lung surgery.
Trial registration:
This study was registered at http://www.chictr.org.cn (ChiCTR2100045614, 19/04/2021).
Research on Co-benefits of China’s Carbon Emissions Trading Scheme
Authors: Liu Zijian , Zhang Yabin , Cai Lian
Published: May 2022

Based on the panel data of 281 prefecture-level cities in China from 2007 to 2017, this paper empirically explores the co-benefits of Carbon Emissions Trading Scheme. The study found that the Carbon Emissions Trading Scheme effectively achieved the coordinated control of carbon dioxide and air pollutants by improving the green production level of the pilot area, reducing the regional industrial output, and promoting the upgrading of the industrial structure, and also had spillover effects on the surrounding cities of the pilot area. The heterogeneity study found that this policy and the "Blue Sky Defense" policy achieved an effective combination, and cities that implemented the two policies at the same time had a stronger synergistic control effect.
Improvement of biohydrogen production from date wastes by Thermotoga maritima using a continuous anaerobic membrane bioreactor
Authors: Saidi Rafika , Hamdi Moktar , Bouallagui Hassib
Published: May 2022

Hydrogen (H 2 ) is a promising energy carrier owing to its environmentally friendly properties and high energy content. The aim of this work is to achieve a continuous H 2 production from a simplified culture medium composed of date wastes (DW) and natural seawater using the marine bacterium, Thermotoga maritima . Increasing the dilution rate ( D ) from 0.02 to 0.25 h -1 in the continuous stirred tank reactor (CSTR) improved the volumetric H 2 production rate ( Q H2 ) from 2 to 17 mmol/L.h. At a D above 0.25 h -1 , a washout of the bacterium cells was observed, resulting in a significant decrease of biomass concentration (BC) and then the drop in Q H2 . The production of H 2 was improved by using a membrane bioreactor (MBR) due to the cell retention in the reactor. At a high D of 0.6 h -1 , the maximum Q H2 was increased from 0.6 to 61.75 mmol/L.h, which is higher than those previously reported on continuous H 2 production from different substrates. Moreover, increasing the hexose concentration in the date juice (DJ) from 30 to 60 mmol/L further enhanced the H 2 production. It allowed a Q H2 . of 70.2 mmol/L.h which is interesting for a large scale production of H 2 from date wastes.