bluuebunny/crossref_metadata_2025 huggingface dataset:
Manajemen Design Thinking dalam Peningkatan Profesionalisme Widyaiswara
Authors: Rahayu Ambar
Published: October 2022

Penelitian ini bertujuan untuk membuktikan bahwa upaya peningkatan profesionalisme Widyaiswara harus menggunakan pendekatan yang berorientasi kepada kebutuhannya dan hasilnya berupa suatu rekomendasi kebijakan bahwa manajemen design thinking adalah pendekatan yang tepat dan efektif untuk segera mewujudkan widyaiswara yang professional. Design thinking yang berpusat kepada manusia (human centered) diharapkan dapat menemukan solusi yang tepat dalam menyelesaikan suatu masalah. Metode ini telah banyak dikembangkan dalam manajemen di perusahaan swasta dan bahkan di beberapa negara untuk membuat inovasi-inovasi yang sesuai dengan kebutuhan dan keinginan pelanggan. Hasil kajian Manajemen design thinking dilakukan melalui 5 tahapan yaitu: empathize, define, ideate dan prototype serta test yang menghasilkan rumusan masalah dan rekomendasi pengembangan profesionalisme widyaiswara sebagaimana yang dibutuhkan dan diinginkan oleh widyaiswara dan para pejabat pimpinan tinggi yang akan membinanya secara berkesinambungan. Model Brain based mentoring bisa menjadi salah satu rekomendasi agar widyaiswara semakin professional. Dengan kajian ini diharapkan akan tergali unsur-unsur yang menjadi kunci keberhasilan inovasi pengembangan profesionalisme bagi widyaiswara di masa yang akan datang.Kata kunci: Profesionalisme; Widyaiswara; Desain Thinking.
Use of pulp and husk of coffee in animal feed
Authors: Oropeza-Mariano Enrique , Ortega Cerrilla Maria Esther , Herrera-Haro José G. , Ramírez-Bribiesca Efrén J. , Salinas-Ríos Teódulo
Published: October 2022

Objective: To review the literature related to the use of husk and pulp of coffee in the feeding of ruminant andnon-ruminant animals.Approximation: The husk and pulp of coffee are by-products that remain after cleaning the bean. These area potential source of pollution; however, they can also be used for animal feed, reducing costs for the producer.Study limitations/implications: Coffee by-products have been used in animal feed globally, especially inthose countries that are the highest producers of this bean. Therefore, it is important to know the resultsobtained there when those by-products are supplied as fed to animals in different conditions.Conclusions: The results obtained vary when these coffee by-products are included in animal diets, dependingon the species and the amount offered.
Наукова діяльність ДНТЦ ЯРБ у 2017 – 2021 роках
Authors: Valigun N. , Vorobey I. , Korniievska O. , Andriushko Yu. , Pecherytsia O.
Published: October 2022

Основними завданнями наукової діяльності ДНТЦ ЯРБ є: одержання конкурентоздатних наукових і науково-прикладних результатів для вирішення пріоритетних завдань з науково-технічної, експертної та інформаційно-аналітичної підтримки державного органу регулювання ядерної та радіаційної безпеки України; аналіз існуючої системи нормування з метою виявлення неврегульованих аспектів, невизначеностей та протиріч; вивчення та аналіз досвіду експлуатації ядерних установок; вивчення, адаптація та запровадження в практику передових методологій виконання аналізу та оцінки безпеки; освоєння сучасних розрахункових кодів і розроблення моделей для отримання знань про перебіг процесів у компонентах реакторної установки і гермооб'ємі, популяризація наукових досягнень підприємства та надання освітніх послуг, направлених на підвищення професійної кваліфікації та професійної перепідготовки спеціалістів та фахівців у сфері використання ядерної енергії, організація видавничої діяльності тощо.

У статті зазначені основні результати наукової діяльності підприємства за 2017 – 2021 роки, зокрема: описані результати досліджень за напрямами: аналіз досвіду експлуатації ядерних установок, інтегральна система нагляду за безпекою АЕС, аварійна готовність і реагування, поводження з радіоактивними відходами, розглянуто досвід підприємства з розроблення розрахунковий моделей, які дозволяють досліджувати процеси в реакторних установках енергоблоків усіх типів, що експлуатуються на АЕС України, описані напрями освітньої та науково-інформаційної діяльності як у межах України, так і за кордоном.

Науково-дослідні та аналітичні роботи є основою формування науково-технічного потенціалу ДНТЦ ЯРБ, удосконалення розрахунково-аналітичних можливостей та дослідження актуальних питань безпеки використання ядерної енергії. Для підтримки належного рівня компетенції ДНТЦ ЯРБ співпрацює з провідними національними науковими та міжнародними організаціями й установами з метою вироблення єдиних наукових і методичних підходів до ядерної та радіаційної безпеки, обміну науковою інформацією.
Magnetic nanoparticle-promoted droplet vaporization for in vivo stimuli-responsive cancer theranostics
Authors: Zhou Yang , Wang Ronghui , Teng Zhaogang , Wang Zhigang , Hu Bing , Kolios Michael , Chen Hangrong , Zhang Nan , Wang Yanjie , Li Pan , Wu Xing , Lu Guangming , Chen Yu , Zheng Yuanyi
Published: October 2022

The development of efﬁcient strategies for in vivo stimuli-responsive cancer treatment and personalized biomedicine is a great challenge. To overcome the critical issues and limitations of traditional protocols using acoustic droplet vaporization and optical droplet vaporization in stimuli-responsive tumor treatment, we herein report a new strategy, magnetic droplet vaporization (MDV), based on nanobiotechnology, for efﬁcient magnetic ﬁeld-responsive cancer theranostics. Perﬂuorohexane (PFH)-encapsulated superparamagnetic hollow iron oxide nanoparticles with a high magnetic-thermal energy transfer capability quickly respond to an external alternating current (a.c.) magnetic ﬁeld to produce thermal energy and raise the temperature of the surrounding tumor tissue. The encapsulated PFH, with a desirable boiling point of ~56°C, can be vaporized to enhance the performance of ultrasound imaging of tumors, as systematically demonstrated both in vitro and in vivo. The magnetic–thermal energy transfer further ablated and removed tumors in mice tumor xenograft models. This unique MDV principle with high versatility and performance is expected to broaden the biomedical applications of nanotechnology and promote clinical translations of intelligent diagnostic and therapeutic modalities, especially for battling cancer. 
Vaporization of perfluorocarbon droplets using optical irradiation
Authors: Strohm Eric , Rui Min , Gorelikov Ivan , Matsuura Naomi , Kolios Michael
Published: October 2022

Micron-sized liquid perfluorocarbon (PFC) droplets are currently being investigated as activatable agents for medical imaging and cancer therapy. After injection into the bloodstream, superheated PFC droplets can be vaporized to a gas phase for ultrasound imaging, or for cancer therapy via targeted drug delivery and vessel occlusion. Droplet vaporization has been previously demonstrated using acoustic methods. We propose using laser irradiation as a means to induce PFC droplet vaporization using a method we term optical droplet vaporization (ODV). In order to facilitate ODV of PFC droplets which have negligible absorption in the infrared spectrum, optical absorbing nanoparticles were incorporated into the droplet. In this study, micron-sized PFC droplets loaded with silica-coated lead sulfide (PbS) nanoparticles were evaluated using a 1064 nm laser and ultra-high frequency photoacoustic ultrasound (at 200 and 375 MHz). The photoacoustic response was proportional to nanoparticle loading and successful optical droplet vaporization of individual PFC droplets was confirmed using photoacoustic, acoustic, and optical measurements. A minimum laser fluence of 1.4 J/cm2 was required to vaporize the droplets. The vaporization of PFC droplets via laser irradiation can lead to the activation of PFC agents in tissues previously not accessible using standard ultrasound-based techniques.
Water at ancient Greek sanctuaries: medium of divine presence or commodity for mortal visitors?
Authors: Von Ehrenheim Hedvig , Klingborg Patrik , Frejman Axel
Published: October 2022

This article presents the newly started project “Water at ancient Greek sanctuaries: medium of divine presence or commodity for mortal visitors?”, the aim of which is to explore water usage at Greek sanctuaries in Archaic to Hellenistic times. In order to do so the project is divided into three separate studies. The first is how water was used in sanctuaries: where was water accessible through natural and man-made infrastructure, for what activities was it utilized, and which of these can be considered ritual and/or utilitarian? The second focuses on the means by which water was utilized, i.e. how was water management infrastructure adapted to ritual and utilitarian needs, and how did the need and access to water shape ritual and utilitarian activity at the sanctuary? The third part is an overarching analysis, combining the first two parts, which will expand our knowledge of perceptions of human activities in the god’s dwelling: how did ritual and utilitarian uses of water differ at a perceptual level?
LSTM-based Multivariate Time-Series Analysis: A Case of Journal Visitors Forecasting
Authors: Saputra Anggie Wahyu , Wibawa Aji Prasetya , Pujianto Utomo , Putra Utama Agung Bella , Nafalski Andrew
Published: October 2022

Forecasting is the process of predicting something in the future based on previous patterns. Forecasting will never be 100% accurate because the future has a problem of uncertainty. However, using the right method can make forecasting have a low error rate value to provide a good forecast for the future. This study aims to determine the effect of increasing the number of hidden layers and neurons on the performance of the long short-term memory (LSTM) forecasting method. LSTM performance measurement is done by root mean square error (RMSE) in various architectural scenarios. The LSTM algorithm is considered capable of handling long-term dependencies on its input and can predict data for a relatively long time. Based on research conducted from all models, the best results were obtained with an RMSE value of 0.699 obtained in model 1 with the number of hidden layers 2 and 64 neurons. Adding the number of hidden layers can significantly affect the RMSE results using neurons 16 and 32 in Model 1.
Evaluation of Employee Acceptance of the IMS Application at PT Sarana Utama Adimandiri: TAM Approach
Authors: Sancoko Sancoko , Prayogi Zahra Shalsabilla , Al Aufa Badra , Yuliawan Rahmat
Published: October 2022

PT Sarana Utama Adimandiri (SUA) which is engaged in the construction sector implements an IMS application in its purchasing activity. This paper aims at describing the evaluation of employee acceptance of the information system at PT SUA using the Technology Acceptance Model (TAM) approach.  TAM has two main variables i.e: perceived usefulness and perceived ease of use which function as independent variables, while the dependent variable is acceptance of IT (integrated management system/IMS applications). The population and sample in this study were all employees of PT SUA, which was used to obtain research data through the distribution of structured questionnaires. The instrument was tested using validity and reliability tests, and data was analyzed by using spearman rank test. This study suggests that there is a strong effect of perceived usefulness and perceived ease of use on acceptance of IT.
Persepsi Pengguna GTSL terhadap Fungsi Estetik, Fonetik, dan Mastikasi di Klinik Feby Dental Care Sulawesi Tenggara
Authors: Chotimah Chusnul , Amiruddin Maqhfirah , Wijaya M. Fajrin , Asmah Nur , Siyu Feby Nadira Amalia
Published: October 2022

Latar Belakang: Masalah mengenai kesehatan rongga mulut mempengaruhi 3,9 miliar orang di dunia. Masalah kehilagan gigi termasuk permasalahan yang berdampak pada kehilangan fungsi estetik, fonetik, dan mastikasi. Kehilangan fungsi estetik, fonetik, dan mastikasi dapat dikembalikan dengan pemakaian gigitiruan. Tujuan: Mengetahui persepsi pengguna GTSL terhadap fungsi estetik, fonetik, dan mastikasi di klinik Feby Dental Care Sulawesi Tenggara. Metode : Observasi dengan rancangan penelitian deskriptif kuantitatif melalui wawancara dan pengisian dalam kuesioner. Hasil : Menunjukkan skor persepsi pengguna GTSL terhadap fungsi estetik, yaitu 242,6 termasuk kategori baik, persepsi pengguna GTSL terhadap fungsi fonetik memiliki skor 246 termasuk kategori baik, dan persepsi pengguna GTSL terhadap fungsi mastikasi memiliki skor 231,6 termasuk kategori baik.Kesimpulan : persepsi pengguna gigitiruan lepasan terhadap fungsi estetik, fonetik, dan mastikasi pada masyarakat yang berkunjung ke klinik Feby Dental Care di Kabupaten Kolaka, Sulewesi Tenggara termasuk kategori baik.
Inovasi Microneedle Patch Pengganti Jarum Suntik Penghantar Vaksin Covid-19 Anak Usia 6-11 Tahun
Authors: Maulida Novi Dwi , Achmad Sri Meidita , Anhar Muhammad Yunanda , Carabelly Amy Nindia
Published: October 2022

Pendahuluan:

Coronavirus Disease

(Covid-19) merupakan penyakit menular sistem pernapasan yang disebabkan oleh Severe Acute RespiratorySyndrome-Coronavirus 2 (SARS-CoV 2). Virus ini menyerang semua  usia termasuk anak-anak. Pemerintah Indonesia menargetkan vaksin Covid-19 untuk 26,5 juta anak usia 6-11 tahun sebagai upaya meningkatkan kekebalan spesifik untuk mencegah Covid-19 dengan menggunakan metodejarum konvensional dan sudah dilakukan di beberapa daerah, tetapi banyak anak yang mengalami ketakutan terhadap jarum suntik. Tujuan:Mengatasi masalah vaksinasi Covid-19 anak yang takut jarum suntik menggunakan metode alternatif microneedle patch. Metode: Penulisan artikel inimenggunakan metode tinjauan pustaka. Tinjauan pustaka yang digunakan berasal dari penelusuran textbooks, jurnal, dan situs web dengan rentangwaktu 2016 hingga 2022. Penelusuran tersebut memperoleh 5 textbooks, 17 jurnal, dan 6 situs web. Kesimpulan: Menuangkan ide dalam berinovasi membuat sediaan dissolving microneedle patch sebagai alternatif penghantar vaksin Covid-19 anak usia 6-11 tahun yang takut jarum suntik untukmempercepat target vaksinasi.
RADIOPROTECTIVE EFFECT OF THE ERACOND ON SPERMATOGENESIS UNDER THE INFLUENCE OF A SINGLE EXTERNAL ACUTE γ-IRRADIATION
Authors:   Institute of Plant and Animal Ecology, Ural Division of Russian Academy of Sciences, Ekaterinburg, Russia, Mamina V.P.
Published: October 2022

Purpose: Experimental evaluation of the radioprotective effect of Erakond on spermatogenesis in BALB/c mice under external acute γ-irradiation. Material and methods: Single external γ-irradiation of males at a dose of 1 Gy was carried out at the IGUR facility (137Cs, dose rate 0.85 Gy/min). Erakond was administered orally for 6 days followed by irradiation 2 weeks later. Violation of spermatogenesis and its correction by eracondas in irradiated animals was assessed by the morphofunctional state of the testes, spermatozoa and the reproductive function of males. Results: In mice on days 16, 24, 48 after irradiation, the number of seminiferous tubules with destructive changes in the spermatogenic epithelium increases from 2.4 to 5.4; 10.2 8.3 % respectively. Erakond contributed to the reduction in the number of seminiferous tubules with destruction to 3.2; 5.1 and 3.5 % respectively. On the 24th, 48th day after irradiation, the number of spermatozoa with an abnormal head increases from 2.8 to 4.8 and 4.5 %; and tail pathology from 4.2 to 8.2 and 7.5 %, respectively, the number of live spermatozoa decreases from 58.1 to 40.5 and 20.0 %, respectively. Erakond contributed to a decrease in the number of spermatozoa with an abnormal head to 3.0; 3.5 %, with tail pathology up to 6.1; 5.3 % and an increase in the number of live sperm up to 50.8; 35.5 % respectively. In mice, on days 16, 24, and 48 after irradiation, the spermatogenea index decreased from 3.4 to 1.5; 0.9 and 2.1, respectively, Erakond contributed to an increase in the spermatogenesis index to 1.9; 2.1 and 2.9 respectively. In mice after irradiation, pre-implantation death at the stages of mature spermatozoa, spermatids, spermatocytes and spermatogonia increased from 24.1 to 41.0; 39.8 and 44.7; 42.0 %, respectively, and post-implantation death at the stages of mature sperm, spermatids, spermatocytes from 16.9; up to 26.5; 27.1 and 38.4 % respectively. The number of live fetuses per female decreased from 5.8 to 3.0; 3.9 and 3.7 respectively. Erakond statistically significantly contributed to the reduction of pre-implantation death at the stages of mature sperm, spermatids, spermatocytes and spermatogonia to 35.6; 33.4; 37.5 and 34.1, respectively, and a decrease in post-implantation death at the stages of mature sperm, spermatids and spermatocytes to 21.6; 20.5 and 28.2 respectively. Conclusion: The data obtained indicate the possible preventive use of Erakond as an effective dietary supplement for the correction of spermatogenesis disorders when exposed to ionizing radiation.
Results of the 69th Session of the United Nations Scientific Committee on the Effects of the Atomic Radiation (UNSCEAR) (Vienna, 9‒13 May, 2022)
Authors:   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia, Akleyev A.V. ,   Chelyabinsk State University, Chelyabinsk, Russia, Azizova T.V. ,   Southern Urals Biophysics Institute, Ozyorsk, Russia, Karpikova L.A. ,   Federal Medical and Biological Agency, Moscow, Russia, Kiselev S.M. ,   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Kononenko D.V. ,   P.V. Ramzaev Saint-Petersburg Research Institute of Radiation Hygiene, Saint-Petersburg, Russia, Melikhova E.M. ,   Nuclear Safety Institute, Moscow, Russia, Romanov V.V. ,   State Atomic Energy Corporation “ROSATOM”, Moscow, Russia, Romanov S.A. ,   Southern Urals Biophysics Institute, Ozyorsk, Russia, Takhauov R.M. ,   Seversk Biophysical Research Centre, Seversk, Russia,   Siberian State Medical University, Tomsk, Russia, Usoltsev V.Yu. ,   State Atomic Energy Corporation “ROSATOM”, Moscow, Russia, Shinkarev S.M. ,   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Published: October 2022

The paper dwells upon the key outcomes of the 69-th Session of the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) which took place during 09-13 May 2022. The delegation of the Russian Federation took part in the Session in on-line format in the form of videoconferences. 153 experts from 31 UNSCEAR member-states as well as the representatives of 13 international organizations participated in the work of the Session. Within the framework of the meetings of the working group and subgroups the documents on the following projects were discussed: R.752 “Second primary cancer after radiotherapy”, R.753 “Epidemiological studies of radiation and cancer” and R.754 “Evaluation of public exposures to ionizing radiation from natural and other sources”. The Committee also discussed interim reports: (R.755 “Evaluation of diseases of the circulatory system from radiation exposure” and UNSCEAR/69/7 “Implementation of public information and outreach strategy for 2020–2024”), Reports of the Secretariat (R.756 “Strategy to improve collection, analysis and dissemination of data on radiation exposure (including considerations of the ad hoc working group on sources and exposure”, UNSCEAR/69/8 “Implementation of the Committee’s Future Programme of Work (2020–2024), and proposals for 2025–2029 period, including consideration of the Committee’s ad hoc working group on effects and mechanisms” and UNSCEAR/69/9 “UNSCEAR use of radiation protection quantities and units”), and Report to the UN General Assembly.
EFFECT OF CHRONIC EXPOSURE AND NON-RADIATION FACTORS ON THE INTRACELLULAR STAT3 CONCENTRATION
Authors:   Urals Research Center for Radiation Medicine, Chelyabinsk, Russia, Kodintseva E.A. ,   Chelyabinsk State University, Chelyabinsk, Russia, Akleyev A.А. ,   Southern-Urals State Medical University of the RF Ministry of Public Health, Chelyabinsk, Russia
Published: October 2022

Purpose: To evaluate the influence of radiation and non-radiation factors on the intracellular concentration of the transcription factor STAT3 in peripheral blood lymphocytes of chronically irradiated residents of the coastal villages of the Techa River in the long-term after the onset of irradiation. Material and methods: The main group consisted of 50 people aged 67 to 84 years old with an average dose of irradiation of the red bone marrow of 727.9±79.1 mGy; thymus and peripheral lymphoid organs – 85.9±13.6 mGy. The comparison group included 25 people aged from 61 to 87 who were not exposed to accidents, whose distribution by sex and ethnicity corresponded to the composition of the main group. Peripheral blood lymphocyte lysates were normalized for total protein concentration prior to enzyme immunoassay. Results: The median intracellular concentration of STAT3 was 167.6 (118.3–240.1) pg/ml in the main group and 147.0 (116.7–179.2) pg/ml in the control group. Conclusion: The intracellular level of STAT3 did not differ significantly between chronically exposed and non-exposed individuals, as well as in people from different dose subgroups. Correlations between the concentration of STAT3 and dose characteristics, gender and ethnicity of the examined people were not found. In people with a red bone marrow dose of 0.85 Gy or more, STAT3 concentration correlated with age at the time of examination (SR= ‒0.67, p=0.01). In other dose subgroups, no correlation was found between the estimated indicator and the achieved age. The results are preliminary.
Research of the Activity of Glutathionperoxidase and the Content of Glutathion in Various Structural and Functional Divisions of the Radrain Brain when Exposed to Radiation
Authors:   Dagestan State Medical University, Makhachkala, Russia, Ismailova F.E. , Nagieva S.E. ,   Dagestan State Medical University, Makhachkala, Russia, Nagiev E.R. ,   Dagestan State Medical University, Makhachkala, Russia
Published: October 2022

Purpose: To study the specific content (per 1 g of tissue) of reduced glutathione and the activity of the enzyme of antioxidant protection glutathione peroxidase conjugated with it in various structural and functional parts of the rat brain when exposed to ionizing radiation at a dose of 6 Gy. Material and methods: The studies were carried out on white outbred rats subjected to a single total γ-radiation at an average lethal dose of 6 Gy. The content of reduced glutathione and the activity of glutathione peroxidase were determined in various structural and functional parts of the brain of irradiated animals: cortex, brain stem, and cerebellum. A group of non-irradiated intact rats served as a control. Results: In control animals, the activity of glutathione peroxidase in the cytoplasm is significantly higher than in mitochondria obtained from cells of the cortex, cerebellum, and brain stem. The content of reduced glutathione in control rats is highest in the cerebral cortex, followed by the cerebellum and brainstem. Significant violations of the studied biochemical parameters in the cerebral cortex, brainstem and cerebellum were found in the dynamics of radiation damage. Thus, in particular, the content of reduced glutathione in the cerebral cortex of rats on the 7th day after radiation exposure decreases to approximately 66 % compared with the indicators of the control group of animals. Conclusions: Exposure to radiation at a dose of 6 Gy leads to a decrease in the content of the antioxidant glutathione in various structural and functional parts of the rat brain, especially on the 7th day after radiation injury. The detected changes in the glutathione content in the dynamics of acute radiation sickness correlate with changes in the activity of glutathione peroxidase, an enzyme directly coupled to this antioxidant.
Total energy expenditure measured by doubly labeled water method in children and adolescents: a systematic review
Authors: Kim Nahyun , Park Jonghoon
Published: October 2022

Total energy expenditure (TEE) is essential for understanding the growth, development, and physical activity of children and adolescents. This study aimed to summarize the existing evidence on TEE measured using the doubly labeled water (DLW) technique in children and adolescents aged 1–18 years. Furthermore, this review compared TEE between obese and normal-weight participants. This systematic review used the PubMed, ScienceDirect, Web of Science, and EBSCO databases. These studies were limited to those published in English between January 2000 and December 2021. Articles presenting objectively measured data on the TEE of children and adolescents aged 1–18 years measured using the DLW method were included. Physical activity level (PAL; TEE/basal metabolic rate [BMR]) and BMR data were also obtained. The search strategy identified 2,351 articles, of which 63 (n=4,283 children and adolescents; 45.4% male) met the selection criteria. The participants in the 10 studies were overweight or obese (n=413). In our study, TEE increased in male and female participants aged 1–18 years. PAL increased with age in males (y=0.0272x+1.3887, r2=0.511) and females (y=0.0199x+1.401, r2=0.335), and the slope of PAL with age did not differ between males and females. The TEE of obese and overweight participants was higher than that of normal-weight participants, but the slope of TEE did not differ between normal-weight (y=132.99x+702.24, r2=0.877) and obese individuals (y=136.18x+1,037.9, r2=0.842). In conclusion, this review provides convincing evidence that daily TEE progressively increases with growth in males and females aged 1–18 years.
MEMBANGUN BRANDING ORGANISASI KARANG TARUNA MELALUI SOSIAL MEDIA
Authors: Kadafi Abdul Rahman , Purnamasari Indah , Tuslaela Tuslaela
Published: October 2022

The rapid development of technology and information in recent years has made the internet a communication tool that is widely used by the community. In the current pandemic period, where there are social restrictions, social media as a digital means, its presence is very important for all circles of society where one of the benefits of social media is as a promotional/branding media including for promotion of organizations, for example by making posts about activities related to social media. positive activities carried out by the organization on social media. Branding is an effort to promote something by forming a self-image so that it gains the trust of the general public. Karang Taruna is a forum for fostering and developing as well as empowering in an effort to develop productive activities by utilizing all the potential available in the environment, both human resources and natural resources that already exist and the use of the internet as one of its social activities. The Karang Taruna 07 management wanted to build organizational branding, but due to lack of knowledge about the importance of building organizational branding and did not know how to make organizational branding so that the Karang Taruna 07 management did not yet have the Karang Taruna 07 organizational branding. administrators and members of the youth organization about organizational branding and how to manage social media to improve the organization's image. In connection with the Covid19 pandemic, the community service program on "Utilization of Social Media for Branding of Youth Organizations RW 07 Kwitang Village" in the form of lectures, discussions and questions and answers and practicums was carried out using online media. From the implementation of this training, it is expected to increase the knowledge and abilities of the participants on how to use social media to build positive organizational branding so that they can support youth activities.
PENDAMPINGAN PENGGUNAAN WEBSITE PELAYANAN ONLINE BAGI STAF PERANGKAT DESA TEGALREJA DI KABUPATEN BREBES
Authors: Hermawan Muhammad Iqbal , Arif Fadhil , Muchyidin Muchyidin , Mulyani Astriana
Published: October 2022

Website merupakan salah satu bagian penting dari sebuah sistem informasi, yang berfungsi sebagai media informasi, sarana publikasi dan media interaksi. Pelayanan yang ada di Desa Tegalreja saat ini masih menggunakan sistem manual, yang mengharuskan pegawai desa melakukan pelayanan di balai desa. Pelayanan di Desa Tegalreja tidak optimal karena jam kerja pegawai desa dibatasi untuk menghindari kerumunan sehingga proses permohonan berbagai surat menyurat menjadi lama dan terhambat. Tujuan dari Penelitian ini adalah menghasilkan sebuah website pelayanan online desa, yang dapat membantu semua masyarakat yang membutuhkan informasi dan Layanan Kemasyarakatan Desa Tegalreja, Kecamatan Banjarharjo, Kabupaten Brebes. Dengan adanya website ini, diharapkan pelayanan desa bisa menjadi lebih optimal. Metode ceramah dan praktik digunakan untuk memberikan pengetahuan dan pemahaman tentang penggunaan website pelayanan online desa. Peserta juga diajak untuk berdiskusi agar lebih mengenal dan termotivasi untuk memanfaatkan dan menggunakan website pelayanan online desa agar pelayanan desa menjadi lebih optimal. Penelitian ini menghasilkan sebuah website pelayanan online desa, yang dapat membantu semua masyarakat yang membutuhkan informasi dan Layanan Kemasyarakatan Desa Tegalreja. Pada website ini terdapat menu yang dapat membantu pelayanan desa untuk masyarakat seperti menu cek data diri, layanan, saran pembangunan dan inventaris hasil pembangunan. Dengan adanya website ini, diharapkan pelayanan desa menjadi lebih optimal.
Acclimation to elevated temperatures in Acropora cervicornis: effects of host genotype and symbiont shuffling
Authors: Indergard MO , Bellantuono A , Rodriguez-Lanetty M , Heng F , Gilg MR
Published: October 2022

Climate change is increasing the average surface temperatures of tropical waters, creating unfavorable conditions for corals. Some species of coral can physiologically acclimate to elevated temperatures, but the degree to which genetic variation underlies differences in this ability is currently unknown. Acclimation to elevated temperatures in coral has been hypothesized to be due to either alterations in the symbiont community or to changes in gene expression. The present study investigated the ability ofAcropora cervicornisto acclimate to elevated temperatures, estimated the heritability of plasticity in upper thermal tolerance, and tested whether observed acclimation patterns could be explained by symbiont shuffling. Coral fragments from a nursery in the Florida Keys (USA) were acclimated at either ambient (27 ± 1°C) or elevated (30 ± 1°C) temperatures and then exposed to a second heat stress (32 ± 1°C) and monitored for mortality. Fragments acclimated to elevated temperatures showed significantly longer lifespans in the subsequent heat stress than did those acclimated at ambient temperature. The ability to acclimate to elevated temperatures differed significantly among coral genets, yielding low, but significant, estimates of broad-sense heritability. A subsequent experiment revealed no changes in either bacterial or dinoflagellate communities of symbionts as a result of acclimation, suggesting that symbiont shuffling did not account for the differences in lifespan between treatments. While estimates of heritability were low, the results suggest that plasticity in upper thermal tolerance significantly differs among coral genets, and that acclimation is likely a result of alterations in gene expression as opposed to symbiont shuffling.
Small town in the border region of Russia: socio-cultural and socio-economic problems
Authors: Biyzhanova Eliza K.
Published: October 2022

The article analyses the main socio-economic and socio-cultural problems that hinder the development of small towns in the Russian border area. Based on qualitative data obtained during research in 2014–2021 in border regions of Russia, the main negative trends were identified, which, in the opinion of local residents, must be eliminated or reduced in the first place in order for a small town to survive. It is shown that most of the small towns in are in a depressed state, with high rates of depopulation. It is concluded that it is necessary to preserve them, since they are not only of cultural and historical value for the reproduction of socio-cultural potential, but also are important strategic territories that can withstand non-military threats and contribute to the preservation of the country’s integrity and its security.
The spirituality in the views of the Soviet and post-Soviet man. Part 1
Authors: Podlesnaia Mariia A. , Ilina Ilona V.
Published: October 2022

The main objectives of this article are to consider the various meanings of the concept of spirituality, religious (Christian) and non-religious. The authors analysed scientific literature, including such authors, who was directly involved in the study of the spirituality of the Soviet person (L. N. Kogan), and many others who devoted themselves to the study of youth in the USSR, including various aspects of its spirituality (V. T. Lisovskii, S. N. Ikonnikova, V. G. Mordkovich, L. Ya. Rubina, M. Kh. Titma, V. I. Chuprov, V. N. Shubkin). As a result of the analysis, a model was developed that makes it possible to talk about the spirituality of the Christian, Marxist, modern new age movement, with the allocation of basic values, the desired ideal, subjects of the process, etc. Correlation with this model should allow us to solve the main goal of the article – to identify how spirituality (in a religious or non-religious context) is understood by the current generation of student youth, what definitions are given to it, and whether there is continuity in this sense with Soviet ideas about spirituality. The authors came to the following conclusion: the meanings of the spirituality of the Soviet period corresponded to the humanism of the Marxist philosophy of «active man», «creator of culture», transforming not only religious tradition, but also various spheres of private life to suit their ideological needs – family and marriage relations, work, leisure, friendship, set the meaning and purpose of the Soviet man.
Bilingualism in culturological projection: the phenomenon of open thinking
Authors: Mojeiko Marina A.
Published: October 2022

Bilingualism is considered as a phenomenon of culture in the context of language contact. A comparative analysis of the phenomena of bilingualism and biculturality is carried out. It is shown that, while creating prerequisites for the biculturality of the subject, bilingualism, however, does not provide it. The function of choosing a language as a choice of social roles, which opens up for a bilingual subject, is shown. The leading role of language choice in the context of communicative adaptation is substantiated. The criteria of language choice are considered: social, socio-psychological and occasional-situational. Adaptive strategies are modelled in relation to speech behaviour in a communicative situation. The significance of the balance between the linguistic and ethnic identity of the subject, on the one hand, and his desire to meet the linguistic expectations of the interlocutor, on the other, is shown. The role of bilingualism as a factor in the emphasis of reflection on language is substantiated. It is shown that in a bilingual context the problems of language development go beyond boundaries of linguistics and become а subject of wide social discussions. The role of bilingualism in literary creativity is revealed, the value of using lexemes of the second language as a tool for enriching artistic expressiveness is shown. It is proved that the more languages in the applied thesaurus of the subject, the richer the emotional palette of his perception of the world. The potential of the language is revealed in relation to not only expressing, but also reflecting emotions, which expands the range of reflexive comprehension of the emotional sphere. On the material of the texts of poetic culture in Belarus, the expansion of the range of expressive possibilities of bilingual subject is substantiated and its significance for the development of artistic culture is demonstrated. The specificity of bilingual subject’s thinking is revealed. Firstly, it is substantiated that in different linguistic projections, a particular fragment of reality can not only turn with its different facets, but in general be configured in a different way, expanding the interpretive potential of the subject and his cognitive capabilities. Thus, the picture of the world of a bilingual subject turns out to be more multidimensional and more plastic. Secondly, it is shown that the possibility of switching the language code, open to a bilingual subject, entails the possibility of appealing to the values of both cultures behind the languages. The thinking of a bilingual subject turns out to be open in relation to more than one option for perceiving reality, which provides not only a richness of perception, but also an expansion of the range of understanding. Such open thinking also means expanding the possibilities of mutual understanding in cross-cultural dialogue, which ensures the effectiveness of both interpersonal communications and the success of international interactions.
Secondary Medical School Students’ Perceptions on Nursing in Kosovo
Authors: Kryeziu Hoxha Blerta , Tahirbegolli Iliriana Alloq , Shabani Arta , Taganoviq Besarta , Brajshori Naime , Tahirbegolli Bernard
Published: October 2022

Aim: The aim of this study is to assess the opinion of secondary medical school students in Kosovo about nursing.

Methods: This descriptive-analytical study was conducted with 1282 secondary medical school students from four regions of Kosovo through random sampling. Data were collected from March to May 2018 by a questionnaire designed for this study from the researchers. It consisted of two sections, the sociodemographic part and the second part about opinion and perceptions about the nursing profession. Continuous variables are summarized as mean and standard deviation (SD), categorical variables are summarized as frequency (n) and percentages (%). Chi square (x2) test is used to analyze the difference between categorical variables

Results: The family had a proactive impact on the choice of the study program for their child. More than half of the students had a favourable opinion of nursing prior to enrolling in secondary medical school. After enrolling in the study program, more than two-thirds of students (72.2%) have a favourable opinion of nursing. More than half of the students (52.6%) believe that the community perceives nursing positively.

Conclusion: Most of the secondary school students have a positive opinion about nursing and think that community have a positive opinion as well. The secondary medical school plays an important role in the improvement of student’s opinion about nursing.

Keywords: opinions, nurses, students, secondary schools, Kosovo
Musculoskeletal System Problems in Dental Practitioners
Authors: Cakir Mustafa
Published: October 2022

Aim: In this study, it was aimed to evaluate the musculoskeletal system problems encountered by dentists working in an oral and dental health center in Kocaeli, Turkey.

Methods: This cross-sectional study including 74 dental practitioners was carried out in 4 Oral and Dental Health Centers in Kocaeli between 15-31 January 2020. A questionnaire was used for data collection. The questionnaire consisted of two sections. The first section concerned the sociodemographic characteristics of the subjects whereas the second section consisted of the Extended Nordic Musculoskeletal Questionnaire. Descriptive statistics are presented as mean (±) standard deviation, frequency distribution, and percentage. The Chi-square test was used to compare categorical variables.

Results: In the study, 70.3% of the subjects were female, 40.5% were aged over 41 years of age, and the average age was 38.1±9.4 years. It was determined that 78.4% of the dental practitioners reported pain in their necks, 50.0% in their shoulders, 67.6% in their backs, 63.5% in wrists and hands, and 68.9% in their lower backs. Moreover, the participants reported experiencing pain severe enough to affect their personal or work lives within the last 12 months in their necks (44.6%), shoulders (23.0%), backs (33.8%), hands and wrists (41.9%), and lower backs (43.2%).

Conclusion: In the study, it was found that dentists have a high frequency of musculoskeletal problems. It is recommended that dentists work in a seated position and exercise between studies.

Keywords: dentists, musculoskeletal diseases, ergonomics
Restructured searls family of estimators of population mean in the presence of nonresponse
Authors: Ahmadini Abdullah Ali H. , Yadav Taruna , Yadav S. K. , Al Luhayb Asamh Saleh M.
Published: October 2022

Nonresponse is a major problem encountered by surveyors when conducting sampling surveys. The present study suggested a naïve modified Searls method for the elevated estimation of the population mean of the primary variable under investigation by utilizing the known auxiliary parameters. The bias along with the mean squared error (MSE) of the introduced estimator is calculated up to the approximation of the first order. We compared the presented estimator with a competing usual unbiased estimator and other competing population mean estimators regarding the issue of nonresponse. The efficiency criteria of the introduced estimator outperforming the other estimators in the competition are determined and verified using five real data sets. The MSEs for the introduced estimator and the other estimators in the competition are calculated for the five considered populations. The estimator with the least MSE or highest percentage relative efficiency (PRE) is recommended for practical exercise in different areas of applications.
Efficacy comparison of Kirschner-wire tension band combined with patellar cerclage and anchor-loop plate in treatment of inferior patellar pole fracture
Authors: Du Bing , Ma Teng , Bai Huanan , Lu Yao , Xu Yibo , Yang Yanling , Zhang Kun , Li Zhong , Li Ming
Published: October 2022

Objective: This study aimed to compare the biomechanical stability and clinical efficacy of the Kirschner-wire (K-wire) tension band combined with patellar cerclage and an anchor-loop plate (ALP) in treating inferior-pole patellar fracture.

Methods: The finite element model was established to analyze the mechanical properties of a K-wire tension band combined with patellar cerclage and ALP fixation in the treatment of inferior patellar pole fracture. The clinical data of 49 patients with patellar inferior-pole fracture (AO/OTA 34 A1) admitted to our hospital from January 2017 to July 2021 were retrospectively analyzed. Among these, 28 cases were fixed with ALPs (ALP group) and 21 cases were fixed with K-wire tension bands combined with patellar cerclage (K-wire group). By reviewing the medical records and follow-up results, we compared the operation time, final knee joint activity, incidence of secondary surgery, postoperative complications, and joint function recovery between the two groups.

Results: The biomechanical analysis of the finite element model showed that the maximum displacement of the K-wire group was 1.87 times that of the ALP group. The maximum stress of the K-wire group was 1.34 times that of the ALP group. The maximum stress of the pole bone in the K-wire group was 13.89 times that of the ALP group. The average follow-up times of the K-wire group and ALP group were similar (p > 0.05), and the average ages of the two groups were similar (p > 0.05). The operation time of the ALP group was significantly shorter than that of the K-wire group (p < 0.05).The final knee joint activity of the ALP group was significantly greater than that of the K-wire group (p < 0.05). The Bostman patellar fracture function score of the ALP group was significantly better than that of the K-wire group at 3 and 9 months after operation (p < 0.05). Postoperative complications of the two groups included 1 case (3.6%) in the ALP group with internal fixation-stimulation complications and, in the K-wire group, 3 cases (14.3%) with internal fixation stimulation complications and 1 case (4.8%) with infection.

Conclusion: The ALP and K-wire tension band combined with patella cerclage models were tested at 500 N, and no damage occurred, indicating that the newly designed ALP is safe in mechanical structure. The ALP has better therapeutic effect in biomechanical stability, postoperative complications, secondary surgery, and knee function. This technique is an effective method for the treatment of inferior-pole patellar fracture.
Changes in soil fungal communities after onset of wheat yellow mosaic virus disease
Authors: Lu Qisen , Hu Cailin , Cai Linna , Wu Chuanfa , Zhang Haoqing , Wei Liang , Zhang Tianye , Hu Haichao , Liu Shuang , Lei Jiajia , Ge Tida , Dai Liangying , Yang Jian , Chen Jianping
Published: October 2022

Rhizosphere-associated microbes have important implications for plant health, but knowledge of the association between the pathological conditions of soil-borne virus-infected wheat and soil microbial communities, especially changes in fungal communities, remains limited. We investigated the succession of fungal communities from bulk soil to wheat rhizosphere soil in both infected and healthy plants using amplicon sequencing methods, and assessed their potential role in plant health. The results showed that the diversity of fungi in wheat rhizosphere and bulk soils significantly differed post wheat yellow mosaic virus disease onset. The structure differences in fungal community at the two wheat health states or two compartment niches were evident, soil physicochemical properties (i.e., NH4+) contribute to differences in fungal community structure and alpha diversity. Comparison analysis showed Mortierellomycetes and Dothideomycetes as dominant communities in healthy wheat soils at class level. The genus Pyronemataceae and Solicoccozyma were significantly are significantly enriched in rhizosphere soil of diseased plant, the genus Cystofilobasidium, Cladosporium, Mortierella, and Stephanonectria are significantly enriched in bulk soil of healthy plant. Co-occurrence network analysis showed that the fungi in healthy wheat soil has higher mutual benefit and connectivity compared with diseased wheat. The results of this study demonstrated that the occurrence of wheat yellow mosaic virus diseases altered both fungal community diversity and composition, and that NH4+ is the most important soil physicochemical factor influencing fungal diversity and community composition.
Roles of follistatin-like protein 3 in human non-tumor pathophysiologies and cancers
Authors: Tian Shifeng , Xu Xiaoyi , Yang Xiaohui , Fan Linlin , Jiao Yuqi , Zheng Minying , Zhang Shiwu
Published: October 2022

Follistatin-like protein 3 (FSTL3) is a type of FSTLs. By interacting with a disintegrin and metalloproteinase 12 (ADAM12), transforming growth factor-β ligands (activin, myostatin and growth differentiation factor (GDF) 11), FSTL3 can either activate or inhibit these molecules in human non-tumor pathophysiologies and cancers. The FSTL3 gene was initially discovered in patients with in B-cell chronic lymphocytic leukemia, and subsequent studies have shown that the FSTL3 protein is associated with reproductive development, insulin resistance, and hematopoiesis. FSTL3 reportedly contributes to the development and progression of many cancers by promoting tumor metastasis, facilitating angiogenesis, and inducing stem cell differentiation. This review summarizes the current pathophysiological roles of FSTL3, which may be a putative prognostic biomarker for various diseases and serve as a potential therapeutic target.