bluuebunny/crossref_metadata_2025 huggingface dataset:
Интеллектуальная система диспетчеризации многономенклатурных производств в режиме реального времени
Authors: Бредихин А.В. , Данилов А.Д. , Веркошанский Д.Е. , Сокольников В.В.
Published: October 2024

Рассматриваются вопросы разработки архитектуры интеллектуальной системы управления производственными ресурсами на базе мультиагентного подхода. Описаны основные компоненты разрабатываемой системы, определены их функциональные модели и технологии реализации. Отдельное внимание уделяется возможности взаимодействия системы не только с программными агентами, но и с физическим оборудованием и производственным персоналом предприятия. Представлены макеты программных интерфейсов для взаимодействия производственного персонала с программными агентами в процессах оперативного перепланирования ресурсов и заказов. Представлены алгоритмы реализации процесса перепланирования загрузки производственного оборудования, а также примеры реализации реакции на события в реальном времени с учетом участия в них программных агентов.
Аппаратно-программный комплекс интеллектуальной системы контроля плотности асфальтобетонной смеси для вибрационных катков
Authors: Прокопьев А.П. , Набижанов Ж.И. , Большаков А.А.
Published: October 2024

Рассмотрено инновационное аппаратно-программное обеспечение для контроля плотности асфальтобетонной смеси для вибрационных катков, позволяющее вычислять значения типовых показателей интеллектуального уплотнения (CMV, CCV, Evib, kb и др.) на основе амплитуды ускорения вибрационного вальца катка и параметров жесткости материала. Приведены результаты апробации предложенного решения в полевых условиях.
Разработка специализированного конструктивно-технологического элемента в среде CAM
Authors: Кугаевский С.С. , Старостин А.П.
Published: October 2024

Одно из наиболее перспективных направлений развития CAM-систем – обработка на основе элементов Feature Based Machining (FBM). Такой подход позволяет значительно ускорить и упростить разработку технологии на станки с ЧПУ благодаря наличию хорошо отработанных технологических алгоритмов для типовых конструктивно-технологических элементов (КТЭ). Но бывает необходимо упростить моделирование обработки специальных нетиповых КТЭ, применение которых характерно для отдельно взятого производства. Рассматривается процесс автоматического распознавания специального КТЭ по 3D-модели в среде ПО NX CAM на примере КТЭ «Гнездо под сменные многогранные пластины». Результаты распознавания создают основу для разработки технологического алгоритма изготовления данного КТЭ, позволяющего сократить время расчета управляющей программы для станка с ЧПУ и оптимизировать производственный процесс.
Применение комплексов цифровой радиографии для выявления дефектов кольцевых сварных соединений трубопроводов
Authors: Глуховской В.А. , Чеглаков Е.Л. , Сысоев А.Н. , Малахов А.И.
Published: October 2024

Приведено сравнение цифровой радиографии с другими методами радиографического контроля, такими как гамма-радиография, радиография на основе запоминающих пластин. Представлен опыт применения метода цифровой радиографии для неразрушающего контроля сварных соединений при обследовании и ремонте трубопроводов на объектах ООО «Газпром добыча Оренбург». Указаны преимущества применяемых комплексов цифровой радиографии, проблемные вопросы, возникающие при использовании данных комплексов, и пути их решения.
МИНИМИЗАЦИЯ УПЛОТНЯЮЩЕГО ВОЗДЕЙСТВИЯ НА ПОЧВУ ДВИЖИТЕЛЕЙ СЕЛЬСКОХОЗЯЙСТВЕННОЙ ТЕХНИКИ
Authors: Гуреев И. И.
Published: October 2024

Разработан новый критерий минимизации уплотняющего воздействия техники на почву. Сущность его заключается в том, что нормированное государственным стандартом допускаемое давление движителей сельскохозяйственных агрегатов на почву выражено посредством вредной интенсивности механического воздействия на нее при выполнении полевых работ. Новый критерий более доступен в практическом использовании. Помимо нормальной нагрузки на почву, он учитывает силовую взаимосвязь между энергосредством и агрегатируемой им машиной, сказывающуюся на уплотняющих свойствах движителей, а потому более адекватно представляет исследуемый процесс в агроландшафте. Требуемые параметры оценки получают, не прибегая к трудоемкому эксперименту, по априорным данным технической характеристики агрегата и свойств почвы, на которой проводят полевые работы. Использование данного критерия позволяет заблаговременно обозначить экологически безопасные условия эксплуатации любого полевого сельскохозяйственного агрегата. Адекватность инновационного критерия подтверждена экспериментально

A new criterion for limiting the compacting eff ect of machinery on soil has been developed. Its essence lies in the fact that the permissible pressure of the propellers of agricultural aggregates normalized by the state standard on the soil is expressed through the harmful intensity of the mechanical impact on it during fi eld work. The new criterion is more accessible in practical use. In addition to the normal load on the soil, it takes into account the strength relationship between the energy source and the machine it aggregates, which aff ects the sealing properties of the propulsions, and therefore more adequately represents the process under study in the agro landscape. The required parameters of the evaluation are obtained without resorting to a laborious experiment – according to the a priori data of the technical characteristics of the aggregate and the properties of the soil on which the fi eld works are carried out. The use of this criterion allows identifying in advance the environmentally friendly operating conditions of any field agricultural unit. The adequacy of the innovation criterion has been confi rmed experimentally.
ТОЛЕРАНТНОСТЬ К ГЕРБИЦИДАМ – ПЕРЕХОД К НОВОМУ ЭТАПУ В ЭВОЛЮЦИИ САХАРНОЙ СВЕКЛЫ
Authors: Балков И. Я. , Логвинов А. В. , Логвинов В. А. , Мищенко В. Н. , Моисеев В. В. , Шувалов А. А.
Published: October 2024

Методами генетики и селекции из гетерозиготных образцов сахарной свеклы созданы фертильные доноры, толерантные к глифосату с устойчивостью 83– 100 %, и стерильные линии с устойчивостью к глифосату 75–100 %. Получены пробные толерантные к глифосату МС гибриды с устойчивостью 77–90 %. Проведено испытание первых устойчивых к глифосату пробных МС гибридов. Выращены семена и корнеплоды для дальнейших исследований.

Methods of genetics and selection of heterozygous samples of sugar beet created fertile donors tolerant to glyphosate with resistance 83–100 % and sterile lines with resistance to glyphosate 75–100 %. Trial hybrids, tolerant to MS glyphosate, with stability of 77–90 % are received. The fi rst trial MS hybrids resistant to glyphosate were tested. Seeds and roots have been grown for further research.
КОМПЛЕКСНОЕ ВЛИЯНИЕ ОСНОВНОЙ ОБРАБОТКИ ПОЧВЫ И СРЕДСТВ ХИМИЗАЦИИ НА ЭКОНОМИЧЕСКУЮ ЭФФЕКТИВНОСТЬ ВОЗДЕЛЫВАНИЯ КУЛЬТУР В ЗЕРНОПАРОВОМ СЕВООБОРОТЕ
Authors: Скорочкин Ю. П. , Воронцов В. А.
Published: October 2024

В 2012–2015 гг. изучали основную обработку почвы на черноземе типичном тяжелосуглинистом в стационарном полевом севообороте пар черный – озимая пшеница – соя – ячмень. Сравнивали пять систем обработки почвы: отвальную (традиционную), ресурсосберегающие (поверхностную, безотвальную) и комбинированные (отвально-безотвальную, отвально- поверхностную), где вспашка занимает 25 %, безотвальная и поверхностная – по 75 %. На фоне обработок применяли пестициды и удобрения, в контроле пестициды не использовали. Наибольшее влияние на развитие растений и продуктивность культур севооборота оказали средства защиты растений. Меньший эффект получен от повышения дозы внесения удобрений. Применение ресурсосберегающих способов основной обработки почвы существенно не повлияло на продуктивность севооборота в сравнении с традиционным отвальным способом обработки почвы. Выявлена целесообразность комплексного применения различных приемов агротехники.

In 2012–2015 the basic treatment of soil in stationary fi eld crop rotation fallow land – winter wheat – soybeans – barley studied on the typical black soil loam. Five tillage systems were compared: conventional tillage (traditional), resource-saving (surface, zero tillage) and combined (conventionalzero tillage, conventional -surface), where the plowing is 25 %, and surface – 75 %. On the background of the treatments under crops used pesticides and fertilizers, pesticides are not used in control. Positive eff ect on plant growth and productivity of crop rotation was provided by the plant protection products. The smaller effect is gained from increase in a dose of application of fertilizers. The use of resource-saving methods of primary tillage did not signifi cantly aff ect the productivity of crop rotation in comparison with traditional conventional method of tillage. The feasibility of integrated use of different agronomic practices has revealed.
ЗАПАШКА СОЛОМЫ ОЗИМОЙ ПШЕНИЦЫ С HUMICOLA FUSCOATRA КАК СПОСОБ ПОВЫШЕНИЯ УРОЖАЙНОСТИ СЕЛЬСКОХОЗЯЙСТВЕННЫХ КУЛЬТУР
Authors: Колесникова М. В. , Безлер Н В.
Published: October 2024

В статье представлены результаты полевых опытов, которые показали, что совместная запашка соломы озимой пшеницы с целлюлозолитическим микромицетом, азотом и питательной добавкой способствует накоплению щелочногидролизуемого азота в почве на протяжении нескольких лет. В результате урожайность сахарной свеклы увеличилась на 25 %, ячменя – на 52 %.

In the article, the results of fi eld experiments are presented. They have shown that winter wheat straw plowing in soil together with celluloselytic micromycete, nitrogen and nutrient additive promotes accumulation of alkaline-hydrolyzable nitrogen in soil during several years. As a result, yield of sugar beet and barley has increased correspondingly by 25 % and 52 %.
СИСТЕМА УДОБРЕНИЯ САХАРНОЙ СВЕКЛЫ В ЗОНЕ НЕУСТОЙЧИВОГО УВЛАЖНЕНИЯ ЦЧР
Authors: Минакова О. А. , Александрова Л. В. , Подвигина Т. Н. , Вилков В. М.
Published: October 2024

Изучено влияние различных систем удобрения на урожайность сахарной свeклы в лесостепи ЦЧР. Установлено, что при внесении нитроаммофоски с гуматом или бором урожайность корнеплодов повышалась на 18,6–63,1 %, а при длительном применении нитроаммофоски 16:16:16 – на 41,7–71,0 %. Применяемые на фоне основного внесения некорневые подкормки микро- элементами увеличивали показатель на 74,8 %, мочевиной – на 48,6 %, почвенные подкормки N27P5K5 + S – на 48,5–79,8 % относительно неудобренного варианта.

Influence of diff erent fertilizer systems upon sugar beet yield in the Central Black-Earth Region foreststeppe was studied. It was determined that, when applying nitroammophoska with humate or boron, root yield increased by 18.6–63.1 %, and using nitroammophoska 16:16:16 for a long time resulted in 41.7–71 % gain. Used against the background of main fertilizer application, foliar applications of microelements increased the index by 74.8 %, and urea applications by 48.6 %, soil applications of N27P5K5 +S by 48.5–79.8 % relatively unfertile.
Efficient Generation of Apo Sirt2 Crystals to Facilitate Investigation of Sirt2 Inhibitor Interactions
Authors: Friedrich Florian , Schiedel Matthias , Swyter Sören , Zhang Lin , Sippl Wolfgang , Schutkowski Mike , Einsle Oliver , Jung Manfred
Published: October 2024

The selectivity pocket is a key binding site for selective inhibitors of the NAD+-dependent lysine deacylase Sirtuin 2 (Sirt2), a promising drug target due to its involvement in diseases like cancer and neurodegeneration. This pocket typically opens only upon binding of long fatty-acylated substrates or selective inhibitors. While crystal soaking could facilitate the structure-guided design of human Sirt2 (hSirt2) inhibitors, the selectivity pocket is absent in current Sirt2 apo structures, and existing soaking systems like Sirt2-ADPribose (ADPR) suffer from disadvantageous crystal contacts that hinder ligand binding to the active site of Sirt2. This necessitates resource-intensive co-crystallization to obtain Sirt2-inhibitor complexes. Here, we developed a method to rapidly produce high-quality Sirt2 apo crystals with an open selectivity pocket, suitable for high-throughput soaking experiments with small molecules. Screening the Maybridge Ro3 library using fluorescence polarization and thermal shift assays, we generated three novel Sirt2-fragment structures. These crystals demonstrated the ability to bind small molecules at the acyl-lysine channel entrance and the cofactor binding site, further validated by soaking with the peptide-based Sirt2 inhibitor KT9 and NAD+, respectively. These findings highlight the broad applicability of our unprecedented hSirt2 apo crystals, supporting structure-activity relationship studies and accelerating the design, development, and optimization of new Sirt2 inhibitor scaffolds.
Advancing Sustainable Ammonia Production via Solventless, Robust, and Thermally Conductive Absorbents
Authors: Nivarty Tejas , Straub William , Onuoha Chinomso , Manno Michael , Schott Jeffrey , Malmali Mahdi , McCormick Alon
Published: October 2024

Sorption-based low-pressure green ammonia synthesis using supported metal halide salts enables efficient interconversion between hydrogen and ammonia, allowing the high hydrogen density and well-established transportation network of ammonia to be used for green energy storage. Magnesium chloride supported on silica gel (MgCl2/SiO2) sorbent has been the subject of much investigation owing to its high capacity, selectivity, and reversibility at temperatures close to reactor conditions; however, MgCl2/SiO2 suffers from low thermal conductivity, which complicates absorber design at larger scales and prolongs absorption-desorption cycle times. We present a scalable, solventless method for supporting MgCl2 on thermally conductive aluminum fibers (MgCl2/Al) - a thermally conductive ammonia sorbent with a high working capacity of 220 mgNH3/gabsorbent. Although the solventless synthesis causes variance in initial-cycle pressure drop and capacity, we show that this stabilizes after cycling. The high thermal conductivity of MgCl2/Al allows for rapid absorption-desorption cycles, enabling easier scale-up. MgCl2/Al also maintains its cyclic capacity up to 50 cycles without any signs of degradation.
The path to the triplet state in LOV domains
Authors: Ghosh Paulami , Ajagbe Stephen O. , Gozem Samer
Published: October 2024

Upon blue light absorption, LOV domains efficiently undergo intersystem crossing (ISC) to the triplet state. Several factors potentially contribute to this efficiency. One often proposed in the literature is the heavy atom effect from the nearby (and eventually adduct-forming) cysteine. However, some LOV domain derivatives missing the cysteine residue also undergo ISC efficiently. Using hybrid multi-reference quantum mechanical / molecular mechanical (QM/MM) models, we investigate the effect of the protein electrostatic environment in a prototypal LOV domain, AtLOV2, compared to the effect of the dielectric of a solvent. We find that the AtLOV2's electrostatic environment is especially well tuned to stabilize a triplet (nN,π*) state, which we posit is the state involved in the ISC step. Other low-lying triplet states having (π,π*) and (nO,π*) character are ruled out based on energetics and/or their orbital shape. The mechanistic picture that emerges from the calculations is one that involves ISC of photoexcited flavin to a triplet (nN,π*) state followed by rapid internal conversion to a triplet (π,π*) state, which is the state detected spectroscopically. This insight into the ISC mechanism can provide guidelines for tuning flavin's photophysics through mutations that alter the protein electrostatic environment and potentially helps explain why ISC (and subsequent flavin photochemistry) doesn't occur more frequently in many classes of flavin-binding enzymes
Formulation and evaluation of nanoemulsion-based nanocream using green ingredients exhibiting enhanced performance characteristics
Authors: Nguyen Daphne , Kumar Manish
Published: October 2024

The present study focuses on the formulation and evaluation of a nanoemulsion-based nanocream using green ingredients, aimed at enhancing performance, stability, and sustainability. The nanoemulsion was developed through the low-energy phase inversion temperature (PIT) method, which successfully protected green bioactive compounds like vitamin E, cinnamon oil, jojoba oil, and peppermint oil from degradation. A series of nanoemulsions were prepared using varying ratios of oils and surfactants and evaluated for thermodynamic stability, transparency, and droplet size. The optimized nanoemulsion, with a mean droplet size of 121.3±1.19 nm and a low polydispersity index (PDI) of 0.094±0.001, demonstrated high uniformity and stability. This optimized nanoemulsion was further used as the cream’s aqueous phase, forming a nanocream that exhibits enhanced permeation of nanoscale bioactives through a membrane and improved overall performance characteristics. In vitro membrane permeation studies revealed that the optimized nanocream achieved a permeation rate of 97.15%, substantially outperforming the control cream. In vitro antimicrobial studies showed comparable efficacy to standard market preparations containing synthetic agents. The nanocream also demonstrated long-term stability over six months, maintaining structural integrity without phase separation or significant changes in pH and spreadability. The nanoemulsion-based nanocream formulated with eco-friendly ingredients hence offers enhanced skin permeation, superior bioactive delivery, and stable performance, making it a promising candidate for topical skincare and antimicrobial applications.
Interaction of Light with Gas-Liquid Interfaces: Influence on Photon Absorption in Continuous-Flow Photoreactors
Authors: Schuurmans Jasper , Zondag Stefan , Chaudhuri Arnab , Claros Miguel , Van der Schaaf John , Noel Timothy
Published: October 2024

Light interacts with gas bubbles in various ways, potentially leading to photon losses in gas-liquid photochemical applications. Given that light is a costly 'reagent', understanding these losses is crucial for optimizing reactor efficiency. In this study, we address the challenge of quantifying these interactions by implementing a method that separately determines the photon flux and utilizes the effective optical path length as a key descriptor of photon absorption. The results reveal an unexpected impact of gas phase introduction in continuous-flow photoreactors. Notably, photon absorption, and consequently the throughput of a photoreactor, can be increased by the introduction of a gas phase. This enhancement arises from the reflection and refraction effects of gas bubbles, which can intensify light intensity in the liquid volume and thereby offset any loss in residence time. The photon absorption losses that were observed were associated with large bubbles and were less significant than anticipated. In contrast, the introduction of small bubbles was found to increase photon absorption, suggesting a potential strategy to optimize photoreactor performance.
Modern hit-finding with structure-guided de novo design: identification of novel nanomolar adenosine A2A receptor ligands using reinforcement learning
Authors: Thomas Morgan , Matricon Pierre G. , Gillespie Robert J. , Napiórkowska Maja , Neale Hannah , Mason Jonathan S. , Brown Jason , Fieldhouse Charlotte , Swain Nigel A. , Geng Tian , O'Boyle Noel M. , Deflorian Francesca , Bender Andreas , de Graaf Chris
Published: October 2024

Generative chemical language models have demonstrated success in learning language-based molecular representations for de novo drug design. Here, we integrate structure-based drug design (SBDD) principles with chemical language models to present a modern hit-finding workflow to go from protein structure to novel small-molecule ligands, without a priori knowledge of ligand chemistry. Using Augmented Hill-Climb we successfully optimised multiple objectives within a practical timeframe, including protein-ligand complementarity. Generated de novo molecules contained both known and promising adenosine A2A receptor ligand chemistry that is not available in commercial vendor libraries, accessing commercially novel areas of chemical space. Experimental validation identified three nanomolar ligands with confirmed functional activity, two of which contain novel chemotypes. Overall, demonstrating a binding hit rate of 88% with 50% of the binders demonstrating confirmed functional activity emphasising the complex relationships in translating binding to downstream pharmacology. Lastly, the two strongest binders were co-crystallised with the A2A receptor revealing their binding mechanisms that can be used to inform future iterations of structure-guided de novo design, closing the AI SBDD loop.
О поведении максимума в случае распределения Бёрра
Authors: Бенинг Владимир Евгеньевич
Published: October 2024

В работе рассмотрено асимптотическое поведение моментов максимальной порядковой статистики в случае распределения Бёрра [1]. Проведено асимптотическое сравнение деятельности страховых организаций, рассматривающих моменты максимальных потерь в качестве общих потерь. Деятельность таких организаций оценивается в терминах асимптотического дефекта. Рассмотрен случай, когда число клиентов страховой компании случайно. В качестве примера рассматриваются усечённые биномиальное распределение и распределение Пуассона, описывающие число случайных факторов (или клиентов), приводящих к потерям.

The paper considers the asymptotic behavior of the moments of extreme values of an organization subjected to risk in the case when the number of factors leading to loss is random. Burr distribution is considered as loss distribution. An asymptotic comparison of the activities of such organizations is carried out in terms of the necessary additional number of such factors (asymptotic deficiency). Two examples illustrating tne obtained results are presented. These examples concern truncated Poisson and binomial distributions.
Los jóvenes y la presión por un futuro exitoso
Authors: Rodríguez Macías María Rosaly
Published: October 2024

El propósito fundamental de la presente investigación ha sido el análisis del pensamiento de los jóvenes quienes comparten sus opiniones acerca de la presión que sienten por lograr un futuro exitoso, para ello se llevó a cabo la recolección de datos mediante una encuesta y posterior a ello se diseñó y construyó una herramienta para analizar sentimientos y organizar datos en grupos, abarcando la recolección y preparación de los mismos. Se seleccionan aquellos que se consideran pertinentes y se definen los algoritmos más coherentes para detectar emociones y clasificar los datos en categorías similares, ajustando y validando cuidadosamente estos datos para asegurar una mayor precisión en el resultado. Este proceso permite comprender las emociones en los textos, identificando agrupaciones que podrían revelar patrones significativos útiles para la toma de decisiones estratégicas, donde en general se pretende llegar a un resultado concreto y específico sobre el impacto que se tiene hoy en día hacia los jóvenes en torno a la presión generada por formar un futuro exitoso. Para esto será de vital importancia la implementación y diseño de un algoritmo basado en machine learning para el análisis de las respuestas para agilizar el resultado y obtención de aproximaciones reales sobre las opiniones y sentimientos de estos jóvenes. A raíz del cuestionamiento y observación de conductas sobre la presión en los jóvenes de entre 18 y 26 años que viven en los diferentes municipios del estado de Aguascalientes, México, el impacto sobre sus vidas no es un reto fácil, por ello es importante mantener un equilibrio sobre la presión que se siente o incluso eliminarla por completo ya que las decisiones tomadas bajo presión y sin un razonamiento previo llegan a ser un poco catastróficas. Acorde con los resultados a obtener se pretende que los jóvenes aprendan a asumir una postura más crítica basada en la disciplina, confianza y desarrollo de su persona en la toma de decisiones a fin de obtener un mayor alcance en sus metas y objetivos, forjando así un futuro exitoso.
Metodología de aprendizaje colaborativo como estrategia pedagógica en el desarrollo de proyectos en la ETITC
Authors: Cortés Sierra Fabián Guillermo , Homez López Oswaldo Iván , García Castellanos Carlos Javier
Published: October 2024

El uso de técnicas de aprendizaje colaborativo en estudiantes de ingeniería fomenta el desarrollo de habilidades comunicativas y de liderazgo, esenciales en entornos laborales donde la retroalimentación y la crítica constructiva son fundamentales. Este estudio presenta una estrategia pedagógica implementada en la Escuela Tecnológica Instituto Técnico Central ETITC, que integra un proyecto conjunto entre asignaturas de distintos semestres y programas: Dibujo Asistido por Computador (segundo semestre, Mantenimiento Industrial), Dinámica (quinto semestre, Procesos de Manufactura) y Mecanismos (octavo semestre, Ingeniería Mecatrónica). La metodología aplicada busca aproximar a los estudiantes a situaciones reales, permitiéndoles aplicar conocimientos de manera práctica, lúdica y creativa para resolver problemas de ingeniería en un ambiente controlado. Al integrar estudiantes de semestres iniciales, intermedios y finales en una misma actividad, se pretende mostrar de forma práctica la implementación de un proyecto de ingeniería, desde el reconocimiento de una necesidad cotidiana hasta la formulación y propuesta de soluciones conceptuales. Lo anterior, como todo proceso educativo, debe ser plausible a una medición tanto cualitativa como cuantitativa, donde el proceso de formación sea medido a lo largo del semestre. Para ello, en cada asignatura involucrada se dio cumplimiento tanto a las competencias como a los resultados de aprendizaje propuestos en el marco de otra serie de actividades, como talleres, quices, exámenes parciales, etc., que garanticen la apropiación del conocimiento por parte del estudiante. Los resultados obtenidos evidencian una articulación exitosa en la implementación, desarrollo y ejecución de proyectos intersemestrales, donde cada grupo de estudiantes, según su nivel de formación, contribuyó significativamente al desarrollo del proyecto durante el primer semestre de 2024.
Modelo de crecimiento de tilapia en sistemas de recirculación para acuicultura
Authors: García Hernández Nicolás , Lizarazo Osorio Alen Santiago , Villamil Diaz Luisa Marcela , Cobo Ángel Martha Isabel , Montes Rodriguez Carlos Daniel
Published: October 2024

El potencial de la acuicultura está basado en mejorar la seguridad alimentaria y de esta manera aportar a los Objetivos de Desarrollo Sostenible 1 (hambre cero) y 12 (producción y consumo responsable). En Colombia, la tilapia representa el 58% de la producción nacional de pescado debido a su rápida reproducción, adaptabilidad y excelente sabor, lo que la convierte en una opción ideal para regiones cálidas como el departamento de La Guajira. Sin embargo, la acuicultura tradicional tiene algunos efectos ambientales negativos, como la contaminación de fuentes hídricas y la invasión de hábitats. Por esta razón, en los últimos años se han venido implementando prácticas que incluyen el uso de sistemas de acuicultura de recirculación (RAS, por sus siglas en inglés). La implementación de estos en zonas áridas y con baja disponibilidad de agua es estratégica (como es el caso de La Guajira), toda vez que posibilita la reducción del consumo de agua en un 95%. Es por ello, que estos sistemas son de alto interés productivo. Dado lo anterior, el objetivo de este estudio es desarrollar un modelo matemático de crecimiento de tilapia en sistemas RAS para la futura implementación de estrategias de cultivo sostenibles. El modelo tiene como finalidad predecir el crecimiento de los peces, el cual depende de parámetros como la temperatura, oxígeno disuelto y amonio, entre otros. Este se calibró usando técnicas de simulación tipo Monte Carlo, empleando datos recolectados en el sistema RAS instalado en el Centro Agroempresarial y Acuícola SENA, localizado en Fonseca, La Guajira. Este sistema cuenta con cuatro tanques de 12 m3, en los que se cultivaron en promedio 1150 animales por tanque. Los peces iniciaron con un peso promedio de 0,5 g y crecieron hasta 350,0 g, aproximadamente. El modelo mostró que la temperatura, el oxígeno disuelto y la concentración de amonio tuvieron un impacto significativo en el crecimiento. Al comparar los datos experimentales con los estimados mediante el modelo se obtuvo un valor de 0.97 para el Coeficiente de Determinación (R2), lo cual muestra la precisión del modelo para predecir el crecimiento de los peces. Se concluye que el modelo desarrollado es efectivo para representar el crecimiento de la tilapia en sistemas de recirculación, lo que sugiere su utilidad para mejorar las prácticas acuícolas y la sostenibilidad del sistema. Las aplicaciones prácticas incluyen la posibilidad de implementar estrategias basadas en el modelo para aumentar la productividad, así como la automatización del proceso a través de sistemas de monitoreo y control, lo que podría mejorar aún más la sostenibilidad y el bienestar del cultivo.
Necesidades de formación a partir del análisis de los contextos interno y externo de un programa de ingeniería de control
Authors: Sánchez Zuluaga Gabriel Jaime , Bohórquez Maldonado Leonardo , Amador Soto Gerardo Jose , Saavedra Montes Andres Julian
Published: October 2024

La ingeniería de control es una carrera transversal a muchas otras ingenierías y, por lo tanto, influye en el desarrollo de los procesos industriales y tecnológicos. Con los nuevos desarrollos tecnológicos en áreas como Internet de las Cosas, Inteligencia artificial, Big Data, entre otras, se hacen evidentes cambios importantes en la automatización y control para permanecer competitivos. El programa de ingeniería de control es protagonista en la denominada cuarta revolución industrial (4RI), por esta razón es necesario realizar cambios curriculares con base en la revisión de los contenidos ya establecidos en los programas académicos y así garantizar que los futuros ingenieros estén preparados para enfrentar los nuevos desafíos. Para estimar las necesidades de formación de los futuros ingenieros de control, este artículo presenta un estudio que identifica el contexto interno por medio de una recopilación exhaustiva de documentos de prospectiva, relacionados con las tendencias y problemáticas del área de interés, así como la selección de diferentes artículos académicos relacionados con nuevas metodologías de enseñanza. Los documentos son producidos por entes gubernamentales, organizaciones profesionales nacionales e internacionales y revistas científicas. Los resultados del análisis de la literatura destacan las necesidades formativas que deben ser cubiertas en un programa de ingeniería de control. Estos requisitos educativos son complementados con el análisis del contexto externo, el cual se establece a partir de una encuesta aplicada a los actores que tienen relación con el programa. El análisis de los datos provenientes de esta exploración se convierte en un conjunto de diferentes necesidades formativas relacionadas con las problemáticas y tendencias reportadas en los documentos. Con estos resultados, se pretende plantear una ruta de las temáticas más relevantes para el programa, planteando posibles cambios curriculares al mismo.
Platform to assess the assistance control performance with the Exo-H3 lower limb exoskeleton
Authors: Ramírez Scarpetta José , González-Mefía Sergey
Published: October 2024

The deployment of a control strategy must take into account several technical aspects to achieve good performance in the control objectives, such as having the feedback variables, either measured or estimated, a deterministic sampling time in the core processing system for calculating the control law, the physical constraints of the actuator, and the data recording from useful variables. To solve the need for deployment and performance assessment in robotic systems, the EUROBENCH European project from the Horizon 2020 program built the first benchmarking framework for exoskeletons, prostheses, and humanoids allowing companies and researchers to test and compare the performance of robots and algorithms at any stage of development by using different testbeds. Then, within one of the EUROBENCH facilities called Wearable Robots, the AssistControl-H3 gait platform was created, which is configured to deploy and assess the performance of assistance controllers for exoskeleton-assisted treadmill gait. The platform has subsystems such as the Exo-H3 lower limb rehabilitation exoskeleton, the BeStable and EXPERIENCE testbeds, and a 3D virtual model of the Exo-H3 exoskeleton. The Exo-H3 is an exoskeleton actuated with servomotors in the hips, knees, and ankles along the sagittal plane; the BeStable testbed is a gait system on an instrumented treadmill, where the useful measurements are ground reaction forces and spatiotemporal gait parameters such as step length, step width and step time. The EXPERIENCE testbed characterizes the user's experience while walking on a treadmill assisted by an exoskeleton; it measures physiological information and thus calculates psychophysiological indicators. Therefore, one full benchmarking scenario was generated from merging these subsystems for control systems deployed into lower limb exoskeletons during given activities.
Effect of Synthetic Surfactants on the Hydrophobicity of Micrococcus luteus Cells 1-i
Authors:   Irkutsk State University, Kazarinova T. F. , Buentueva U. V. ,   Irkutsk State University, Zhdanova G. O. ,   Irkutsk State University
Published: October 2024

The influence of synthetic surfactants belonging to different classes on changes in the hydrophobicity of the cell surface of the bacterial strain Micrococcus luteus 1-i was studied. The hydrophobicity index was studied by the MATH method (microbial adhesion to hydrocarbon). Four representatives of different classes of surfactants were tested: sodium dodecyl sulfate (anionic surfactant), cetyltrimethylammonium bromide (cationic surfactant), Tween-80 (nonionic surfactant) and polyvinyl alcohol (polymer surfactant). It was shown that the hydrophobicity of M. luteus 1-i cells changed to varying degrees under the influence of the studied surfactants. A comparison of their molar concentrations, which have a negative effect on the hydrophobicity parameter, made it possible to rank these compounds in the following order (as the degree of reduction in hydrophobicity decreases): Tween-80 > sodium dodecyl sulfate > cetyltrimethylammonium bromide. The experimental data obtained are of practical interest in terms of studying the characteristics of the interaction of the tested bacterial strain M. luteus 1-i with electrode surfaces and substrates (components of wastewater and waste) in microbial fuel cell technology.
Inhibitory Analysis of Protease Preparations of Cell-Free Fractions of Cholera Vibrios
Authors:   Irkutsk Anti-Plague Research Institute of Siberia and Far East of Rospotrebnadzor, Kozlov S. N. , Markov E. Yu. ,   Irkutsk Anti-Plague Research Institute of Siberia and Far East of Rospotrebnadzor, Nikolaev V. B. ,   Irkutsk Anti-Plague Research Institute of Siberia and Far East of Rospotrebnadzor, Mironova L. V. ,   Irkutsk Anti-Plague Research Institute of Siberia and Far East of Rospotrebnadzor, Korneva A. V. ,   Irkutsk Anti-Plague Research Institute of Siberia and Far East of Rospotrebnadzor, Doroshchenko A. A. ,   Irkutsk Anti-Plague Research Institute of Siberia and Far East of Rospotrebnadzor
Published: October 2024

One of the important areas of research into the pathogenesis of diseases caused by pathogens of especially dangerous infections is the study of the system of hydrolytic enzymes. It has been established that hydrolytic enzymes of pathogenic microorganisms enhance their pathogenicity (virulence) and participate in the processes of adaptation to unfavourable environmental factors. Cholera vibrio has previously electrophoretically detected hydrolases belonging to different subclasses and established differences in their spectrum in strains with different epidemic significance. Therefore, the study of their characterisation (type determination using activator/inhibitor assays) is a relevant area of research. The inhibitor analysis of secreted proteases of cholera vibrio strains of O1 serogroup El Tor biovar and O139 serogroup determined that the proteases include serine and metalloproteases.
Influence of Urgent Training Effect on Adaptation Parameters in Qualified Freestyle Wrestlers
Authors:   Irkutsk State University, Yuryeva А. A. , Gutnik I. N. ,   Irkutsk State University, Kurashova N. A. ,   Scientific Center for Family Health and Human Reproduction Problems, Kolesnikova L. I. ,   Irkutsk State University,   Scientific Center for Family Health and Human Reproduction Problems
Published: October 2024

An analysis of the results of assessing the urgent training effect of qualified freestyle wrestlers in the preparatory period of the annual training cycle is given. As parameters for the analysis of the urgent training effect, subjective and objective research methods were used, such as a change in the resting heart rate, an athlete's assessment of readiness to train, the ratio of fatigue to recovery, an assessment of the training day by the coach, and a biochemical blood test to clarify the level of the creatine phosphokinase enzyme. The results of the control of the urgent training effect according to the four-component scale indicate that the athletes recover sufficiently and have an average readiness to train. To assess the objective indicators of the urgent training effect, documentary materials were analyzed – the results of a biochemical blood test for the concentration of the creatine phosphokinase (CPK) enzyme. Determination of the total activity of CPK in the blood serum after exercise makes it possible to assess the degree of damage to the cells of the muscular system, myocardium, and other organs. The higher the stress (severity) of the transferred load for the body, the greater the damage to cell membranes, the greater the release of the enzyme into the peripheral blood.In most wrestlers, the creatine phosphokinase index corresponds to the average index of physical activity stress and does not represent negative changes in the biochemical component of the athletes' body. Consequently, in these athletes, the urgent training effect has been successfully implemented. Athletes were identified whose stress level in terms of CPK is above average and high, which corresponds to the body’s underrecovery after previous loads, respectively, subsequent training loads will deplete the body’s reserve capabilities and will not cause an increase in the wrestlers’ body fitness.
Morphometric Parameters of Oxytropis popoviana Peschkova from Natural Populations of the Northwestern Coast of Lake Baikal (Irkutsk Region, East Siberia)
Authors:   Irkutsk State University, Stepantsova N. V.
Published: October 2024

Morphometric parameters (plant height, number, length and width of vegetative and generative organs) of living specimens of the rare endemic plant Oxytropis popoviana Peschkova from reference natural populations of the northwestern coast of Lake Baikal were studied for the first time. The variability of various signs has been studied. The obtained morphometric parameters of O. popoviana were compared with those given in the protologue of this species and with the parameters of the closely related species Oxytropis grandiflora (Pall.) DC. The study of the variability of signs for use in diagnostics showed that the most stable parameters of the flower are: the length and width of the flag, the length and width of the boat, the length and width of the cup, the length of the wings. The length and width of the beans also change little. The lengths of the tip of the boat and the bean, as well as the signs of the leaves, are the most variable. A comparison of the morphometric parameters of O. popoviana obtained by us with the values indicated in the O. popoviana protologue, as well as with the data for O. grandiflora, showed the uniqueness of O. popoviana plants in the natural populations of Rytiy and Pokoyniki capes. According to the signs of the vegetative sphere, they approach O. grandiflora, and according to most quantitative and qualitative generative signs they correspond to the parameters of O. popoviana indicated in the protologue, or approach them.
Static Performance and Peculiarities of Functional Response to Muscle Load of Young Men of Different Somatotypes
Authors:   Novosibirsk State Pedagogical University, Prikhodko A. Yu. ,   Novosibirsk State Technical University,   Research Institute of Neuroscience and Medicine, Gerasimov S. N. ,   Novosibirsk State Technical University, Krivoshchekov S. G. ,   Research Institute of Neuroscience and Medicine,   Novosibirsk State Pedagogical University, Aizman R. I. ,   Novosibirsk State Pedagogical University,   Novosibirsk Research Institute of Hygiene of Rospotrebnadzor
Published: October 2024

The aim of the research is to study the strength characteristics and type of functional response to muscle load of young men of different somatotypes, depending on physical fitness. The study involved 128 practically healthy young men aged 18 to 23 years. The group of subjects included qualified athletes, swimmers, as well as healthy young men engaged in physical culture within the framework of the university program. Somatotype was assessed in all subjects using Hit-Carter method, arm strength and static endurance – according to Rosenblat method, and the type of functional response with Kaznacheev method. It was found that young men of the endomorphic somatotype were characterized by a strong physique, a larger amount of skin-fat folds, low values of the muscle index, less endurance of the hands and did not demonstrate a distinct preference for the type of functional response. The young men of the ectomorphic somatotype had a less robust physique, a smaller thickness of the skin-fat folds, greater endurance of the hands and gravitated to the stayer type of functional response of the neuromuscular apparatus. The young men of the mesomorphic type significantly differed from representatives of other somatotypes by greater arm strength, sprinting type of functional response and, according to other morphofunctional indicators, occupied an intermediate position between endo- and ectomorphs. The analysis revealed functional connections between the components of meso- and ectomorphy, maximum static muscular endurance and types of functional response. The revealed significant differences and interrelations between the morphofunctional parameters under consideration and the types of functional response indicated the phenotypic features of individual development characteristic for each somatotype group. The obtained data should be taken into account when choosing the specifics of physical culture and sports activities.
Combining the Servqual and Kano Models to Find Out How Satisfied Customers are with Swab and PCR Services
Authors: Irawati Desrina Yusi , Junita Elisabet
Published: October 2024

Swabs and PCR are ways to track patients infected with COVID-19. One private swab and PCR service provider in Surabaya offers swab and PCR tests with fast results and is open 24 hours a day. This research aims to determine service quality performance, identify the causes of consumer dissatisfaction, and identify service attributes that must be maintained and improved for Swab and PCR services in Surabaya. This research uses an integration of the Servqual and Kano methods. The integration of Servqual and Kano determines the service attributes to be improved. Data was obtained from a questionnaire using the five-dimensional Servqual approach, then calculated to get a gap value and categorized using the Blauth formula. The Servqual gap and the Blauth formula's category values are combined to make action decisions. The results state that swab and PCR service providers still need to improve all factors used in this research. Three attributes fall into the weak and indifferent category, so the decision that needs to be made is to ignore them because they do not affect consumer satisfaction and are not a priority for improvement. The other twenty-one attributes fall into the weak and one-dimensional category, meaning companies must improve these attributes to satisfy consumers. Companies need to make improvements to ensure better service, including increasing the number of medical officers to reduce fatigue and queues and providing training on medical procedures and communication skills for medical officers.
The Measurement of Job Stress Levels on Study Concentration in Students Who Study While Working (Case Study: Gunadarma University Postgraduate Students)
Authors: Lestari Shyntiya Ayu , Putri Dian Kemala
Published: October 2024

The concentration of studies is very important to support students in understanding the theory and understanding the concepts during learning activities so this needs to be noted so that students can achieve good learning outcomes. Studying while working will certainly cause serious problems to the process of activities on campus and at work. Problems that often occur are piling up tasks, difficulty managing time, fatigue, disputes between colleagues and superiors, a toxic work environment, limited rest time, being expelled from university, and experiencing a delay in graduation. These can trigger job stress for students because they have to do two activities in their daily lives. This study aims to find out the effect of job stress levels on study concentration in working students. In addition, this study analyzes the factors that influence job stress and study concentration. The method used is quantitative analysis with a non-probability sampling technique with a purposive sampling technique. The analysis of data carried out was a Chi-Square test and t-test. Based on the results shows that students who study while working have a very high level of job stress which causes a decrease in learning concentration in students. In addition, several factors influence job stress and study concentration, namely gender, age, type of work, and length of work duration. This research contributes to providing an overview and consideration to students about students who study while working.