bluuebunny/crossref_metadata_2025 huggingface dataset:
Sınır ve Boşluk: Klasik İslam Sanat Eseri-Çerçeve-Duvar Arasındaki İlişkiye Dair Felsefi Bir Analiz
Authors: TATAR Burhanettin
Published: June 2022

Klasik İslam sanat eserlerinin -eskiden farklı olarak- bir çerçeve içine konulması ve seküler mekanlara asılması ne anlama gelmektedir? Kimi zaman çerçeveden uzak bir şekilde sokak duvarları, metro girişleri gibi kamuya açık mekanlarda görünür olması, onların modern hayat ile ilişkisinde ne tür rol oynamaktadır? Klasik İslam sanatlarının geleneksel anlatılardan/yorumlardan kısmen uzaklaşarak modern hayata ve mekanlara dahil olmak istemesi, onların anlam dünyasını nasıl dönüştürmektedir? Bu yazımızda yukarıdaki soruları daha iyi kavramamıza imkan verecek şekilde, sanat eseri-çerçeve-duvar arasındaki ilişkiye klasik İslam sanatlarına özel referansla değinmeye çalışacağız. Yazımızda ileri süreceğimiz iddia şudur: Klasik İslam sanatları, Ortaçağda gördüğümüz şekliyle, konumlandırıcı güç olma vasfını önemli ölçüde yitirerek, seküler mekanlarda konumlandırılan bir şeye dönüşmektedirler. Bu yüzden onlar her ne kadar bir yönüyle sanat eseri vasfını korusalar da, diğer yönüyle dekorasyon (ornament) karakterine bürünmektedirler.
Effects of explicit instruction in nominalisation on ESL learners’ academic writing
Authors: Hu Guangwei , Perez Miller Reyes
Published: June 2022

Extant research has highlighted the essentiality of grammatical metaphor (GM) as a linguistic resource in academic writing. Drawing on Systemic Functional Linguistics (SFL), this study investigated the relationship between explicit instruction in nominalisation as one type of GM and ESL learners’ mastery of this key resource. Adopting a true experimental design, the study involved 38 Filipino professionals in Singapore who needed to pass IELTS for academic or professional purposes. The students in the experimental group received nine hours of explicit instruction in various aspects of nominalisation, whereas those in the control group received the same amount of instruction focusing on error analysis, formality of language, as well as the use of the Academic Word List (AWL) and the British National Corpus. Comparisons between the texts produced by the experimental and the control group in response to timed writing tasks revealed quantitative and qualitative differences in the frequencies of nominalisations employed, the lexical density of texts, and the quality of essay organisation. The findings constitute new evidence of the importance of GM as a powerful linguistic resource for helping learners write texts that are valued in academia.
Optimal condition for Propagation and Growing of Dendrobium thyrsiflorum
Authors: Cuc Nguyen Thi Kim , Oanh Nguyen Thi , Diem Nguyen Thi , Tho Nguyen Huu
Published: June 2022

Dendrobium thyrsiflorum is a medicinal orchid that is being gradually destroyed due to over-exploitation. This research focuses on in vitro production of D. thyrsiflorum plantlet under optimal acclimatization conditions. The results of the study showed that the best medium for seed germination was MS basal medium (full-strength MS nutrient plus 100 ml L-1 coconut water; 7 g L-1 agar, 30 g L-1 sucrose, and 0.5 g L-1 active charcoal) supplemented with 60 g L-1 mashed sweet potatoes, which induces 97.8% of seed germination. The shoot was well developed in MS basal medium supplemented with 60 g L-1 mashed sweet potatoes and 0.4 mg L-1 6-Benzylaminopurine (BA) and, corpulent and green in shoot morphology. The shoot multiplication rate was greatest on MS basal medium supplemented with 0.4 mg L-1 BA and 0.4 mg L-1 Kinetin with 4.53 times, and the shoot height was reported at 3.45 cm after 8 weeks of subculture. Further, The shoot was 100% rooting, with an average of 4.51 roots/shoot and 5.34 cm per root in length when the shoot was implanted on MS basal medium plus 60 g L-1 mashed sweet potatoes and 0.75 g L-1 active charcoal. Especially, plantlets after transplanting to the orchid net house reached a 94.8% survival rate on tree fern after 24 weeks. Hence, the results of the study suggested a successful production of D. thyrsiflorum plantlet on the selected media compositions.
Peculiarities of postural disorders and connections with the blood compliment system in the case of falls syndrome in the elderly
Authors:   Fyodorov Eye Microsurgery State Institution, Gurko Tatyana S. , Agarkov Nikolay M. ,   Southwest State University, Lev Inna V. ,   Fyodorov Eye Microsurgery State Institution, Korovin Evgeniy N. ,   Voronezh State Technical University, Leon German F. ,   Southwest State University
Published: June 2022

Background: Natural and premature aging is accompanied by postural disorders, which are aggravated in patients with ophthalmic pathology and lead to the occurrence of the falls syndrome, but remain insufficiently studied in patients with angle-closure glaucoma with a change in the blood compliment system. The aim of the study:To study postural disorders and connections with the blood compliment system with angle-closure glaucoma. Materials and methods: The study was conducted in 62 elderly patients with falls syndrome and angle-closure glaucoma (main group) and 49 60-74-year-old patients with no falls and angle-closure glaucoma and other eye diseases. Postural disorders were studied using the Sensori Organization Test on a computer stabilometric complex in 6 functional tests (COND 1-6) and with an assessment of the somatosensory system, visual analyzer and the use of visual information in ensuring postural balance. The components of the blood compliment system were examined by enzyme immunoassay. The study of correlations was checked by the correlation method using the program "Statistica 10.0". Results: Negative changes in postural balance in the elderly with falls syndrome and angle-closure glaucoma were detected in all 6 functional tests, but the most pronounced deterioration was noted in functional tests COND 2, COND 4 and COND 6. There was a decrease in the participation of the visual analyzer, somatosensory system and preference for using visual information in control of postural balance. Postural disturbances in patients with falls syndrome and angle-closure glaucoma are more associated with C3 C3a and C5a components of the blood compliment system and especially in functional tests COND 4, COND 6.
Pharmacological characteristics of intranasal dosage forms containing Ginkgo biloba extracts
Authors:   Volgograd State Medical University, Kovtun Elena V. , Stepanova Eleonora F. ,   Volgograd State Medical University, Chernikov Maxim V. ,   Volgograd State Medical University, Pozdnyakov Dmitry I. ,   Volgograd State Medical University, Shabanova Natalia B. ,   Volgograd State Medical University, Gerashchenko Anastasia D. ,   Volgograd State Medical University
Published: June 2022

Background: This article reviews the pharmacological characteristics of developed dosage forms for intranasal administration. The influence of the type of dosage form on the efficacy of the drug is significant. Gel-like structures are interesting objects for research. Interest in understanding the nature and properties of such structures is due to the variety of effects observed when gels are used. The active ingredient in the studied forms is ginkgo biloba extract obtained by ultrasonic extraction followed by thickening. The object of comparison is standardized dried ginkgo biloba extract (EGB 76). The study of cerebrotropic activity of the developed gels was conducted on the model of bilateral occlusion of the common carotid arteries. The studied objects and the reference preparation were administered therapeutically after modeling cerebral ischemia once a day for 3 weeks. Aim of the study: To evaluate specific pharmacological activity of the developed dosage forms of ginkgo biloba. Materials and Methods: Studies were performed in an appropriate design by simulating cerebral ischaemia in rabbits using simultaneous bilateral occlusion of the common carotid arteries. Changes in cerebral blood flow velocity were performed by Doppler using an appropriate transducer and software package. The data obtained were statistically processed using an application software package. Results: Conducted investigations revealed that under conditions of experimental cerebral ischemia simulated by simultaneous occlusion of the common carotid arteries in large laboratory animals (rabbits), the use of the developed dosage forms promoted the reduction of the severity of neurological deficit, the restoration of cerebral hemodynamics and pro/antioxidant balance in the hippocampus. Conclusions: Developed nasal gels based on chitosan and sodium alginate are promising agents for chronic cerebrovascular accident with antioxidant mechanism of action and therapeutic potential similar to oral administration of standardized ginkgo biloba extract - EGB 761
Estado social digital: a transformação digital dos serviços sociais
Authors: Strapazzon Carlos Luiz
Published: June 2022

A digitalização dos serviços sociais foi impulsionada nos últimos anos, tanto por agências internacionais quanto por governos democráticos. Durante a pandemia da Covid-19 essa tendência, que evoluía em ritmo moderado, cresceu velozmente a ponto de criar, em menos de dois anos, um mundo novo para serviços sociais. O estudo apresenta uma revisão do estado atual das discussões que envolvem direitos sociais e a transformação digital nas formas de prestações estatais. Analisa um caso julgado pela justiça holandesa e três relatórios técnicos de organismos internacionais sobre o estabelecimento, definitivo, do Estado Social Digital a partir de 2019. Parece que o sistema de segurança social de nenhuma democracia será capaz de resistir ao fascínio das transformações digitais. Há uma firme aceitação de que o capitalismo entrou em sua fase digital e que é dever do Estado dar à sociedade serviços correspondentes. Esse pensamento alcançou os programas sociais.
Digitalization of educational activities during the coronavirus infection
Authors: Velikaya Tatyana
Published: June 2022

The transition to the digital economy, the new needs of the labor market, the existing digital inequality actualize the problems of digitalization of education, which is becoming the most important condition for the development of the economy of knowledge. Considering that the spread of coronavirus infection has transformed various aspects of social life and forced us to accelerate the transition to distance learning, we propose to consider the features of digitalization of the educational environment of the university on the example of the HSE. The article is based on the results of two studies: the All-Russian survey of students "Distance Education 2021" and the author's research conducted at the HSE (Distance 2021). Within the framework of these empirical projects, the goal was to find out the main directions of digitalization of universities in Russia, the main barriers to digitalization of the educational environment, as well as satisfaction with distance learning and the factors that determine this satisfaction.
The level of digital technology proficiency, a quick and painless transition to a distance learning format shows the high readiness of the Russian education system to the new standards of the educational process. Students from different regions of the country showed a high level of satisfaction with the quality of online education, and when building their educational trajectories, they would prefer hybrid forms combining off-line and on-line classes.
The research results have shown that satisfaction with distance education is generally lower than satisfaction with education at the HSE, and the main factors influencing satisfaction are organizational, not value-motivational. Some differences were revealed in the assessments of the educational process among students of different directions.
Effectiveness of Kenikir (Cosmos caudatus Kunth.) Leaf Extract on Duodenal Epithelial Damage of Aspirin Induced Male White Rats (Rattus norvegicus)
Authors: Alfina Siti , Febriani Husnarika , Syukriah Syukriah
Published: June 2022

Aspirin or acetylsalicylic acid is one of the most common types of anti-inflammatory drugs used by people to relieve pain and inflammation. However, aspirin consumption can cause damage to the duodenal mucosal epithelium because it is acidic and inhibits the production of prostaglandins that are important in maintaining the mucosa. Duodenal damage due to aspirin consumption can be repaired using natural ingredients from plants with antioxidant and anti-ulcer effects, one of which is kenikir (Cosmos caudatus Kunth.) leaves. This study aims to determine the effectiveness of kenikir leaf extract against aspirin-induced histopathology and histomorphometry of the duodenum of male white rats. The research design used a completely randomized design (CRD) with 5 treatments and 5 replications. The treatments consisted of a normal group (feed and drink ad libitum), an aspirin group (induction of aspirin 200 mg/kgBW), and a treatment group with kenikir leaf extract at a dose of 700 mg/kgBW, 800 mg/kgBW, and 900 mg/kgBW. Preparation of histopathological preparations of the duodenum used the paraffin method with Hematoxylin-Eosin staining. Data were analyzed using one-way ANOVA and Duncan's follow-up test. The results of the histopathology study showed a significant difference (p<0.05) on the integrity score of duodenal mucosal epithelial cells. Histomorphometry had a significant effect on the height villi, basal width, apical width, and villous area (p<0.05). It can be concluded that administration of kenikir leaf extract at a dose of 900 mg/kgBW was most effective in improving the histopathology and duodenal histomorphometry of aspirin-induced male white rats.

Keywords: aspirin, duodenum, kenikir (Cosmos caudatus Kunth.)
Liver transplantation and nonalcoholic steatohepatitis: the state of the art
Authors: Gitto Stefano , Mannelli Nicolò , Tassi Andrea , Gabrielli Filippo , Nascimbeni Fabio , Andreone Pietro
Published: June 2022

Nonalcoholic fatty liver disease (NAFLD) represents one of the most diffuse liver diseases worldwide. It is a condition ranging from liver steatosis to non-alcoholic steatohepatitis (NASH) and NASH-related cirrhosis. Recently, the term metabolic dysfunction-associated fatty liver disease has been proposed in place of NAFLD, accenting the metabolic and cardiovascular risks that accompany hepatic disease. In the last decades, NASH and NASH-related cirrhosis have been the fastest growing indications for liver transplantation (LT), and they will probably overcome the other indications in next future. After LT, recipients show an important increase in body weight due to a greater caloric intake, partially because of the metabolic influence of immunosuppressant drugs, favoring the development of diabetes mellitus, dyslipidemias, and arterial hypertension. These metabolic complications will, in turn, elevate cardiovascular risk in this population. In this review, we analyze the main metabolic challenges of both pre-and post-LT periods.
Comparative Analysis of the pIgR Gene from the Antarctic Teleost Trematomus bernacchii Reveals Distinctive Features of Cold Adapted Notothenioidei
Authors: Ametrano Alessia , Picchietti Simona , Guerra Laura , Giacomelli Stefano , Oreste Umberto , Coscia Maria Rosaria
Published: June 2022

The IgM and IgT classes were previously identified and characterized in the Antarctic teleost Trematomus bernacchii, a species belonging to the Perciform suborder Notothenoidei. Herein we characterized the gene encoding the polymeric immunoglobulin receptor (pIgR) in the same species and compared it to pIgR of multiple teleost species belonging to five perciform sub-orders, including 11 Antarctic and one non-Antarctic (Cottoperca gobio) notothenioid species, the latter living in less cold periantarctic sea. Antarctic pIgR genes displayed particularly long in-trons marked by sites of transposable elements and transcription factors. Furthermore, analysis of T. bernacchii pIgR cDNA unveiled multiple amino acid substitutions unique to Antarctic species, all introducing adaptive features, including N-glycosylation sequons. Interestingly, C. gobio shared most features with the other perciforms rather than with the cold adapted relatives. T. bernacchii pIgR transcripts were predominantly expressed in mucosal tissues, as indicated by q-PCR and in situ hybridization analysis. These results suggest that in cold adapted species pIgR preserved its fundamental role in mucosal immune defense, although remarkable gene structure modifications occurred.
Heterogeneous Dynamic Correlation Research Among Industrial Structure Distortion, Two-way FDI, and Carbon emission intensity
Authors: You Jiansheng , Ding Guohan , Zhang Liyuan
Published: June 2022

In this paper, industrial structure distortion, two-way FDI and carbon emission intensity are brought into a unified research framework, and based on China's panel data from 2011 to 2020, empirical tests are conducted employing Exploratory Spatial Data Analysis (ESDA), spatial econometric model and intermediary effect test. The results show the following. Firstly, China's industrial structure distortion index shows a downward trend. The industrial structure distortion index is the highest in the west, followed by the middle, and the lowest in the East. Secondly, the relationship between carbon emission intensity and economic development shows a "decoupling" effect and keeps decreasing year by year. The spatial disparity is remarkable, showing the pattern of "the east leading, the middle catching up and the west lagging ". At the provincial level, except in Xinjiang province, the carbon emission intensity of other provinces showed different degrees of decline. In terms of spatial distribution, the polarization characteristics of carbon emission intensity are significant, and the traditional spatial distribution pattern has been broken. Thirdly, there is a positive spatial correlation between China's industrial structure distortion, two-way FDI and carbon emission intensity. The distortion of industrial structure will not only lead to the increase of local carbon emission intensity but also produce reverse spillover to adjacent areas. IFDI and OFDI provide a strong driving force for the decline of carbon emission intensity. IFDI promotes the decline of carbon emission intensity in adjacent areas, while OFDI will increase the carbon emission intensity in surrounding areas. The interaction of IFDI and OFDI can significantly reduce the carbon emission intensity of local and adjacent areas. Fourthly, the results of intermediary effect analysis show that two-way FDI is the two channels of industrial structure distortion affecting carbon emission intensity. Industrial structure distortion can affect the transmission mechanism of carbon emission intensity by affecting two-way FDI.
Transformers Improve Breast Cancer Diagnosis from Unregistered Multi-View Mammograms
Authors: Chen Xuxin , Zhang Ke , Wang Ximin , Abdoli Neman , Gilley Patrik W. , Liu Hong , Zheng Bin , Qiu Yuchen
Published: June 2022

Deep convolutional neural networks (CNNs) have been widely used in various medical imaging tasks. However, due to the intrinsic locality of convolution operation, CNNs generally cannot model long-range dependencies well, which are important for accurately identifying breast cancer from unregistered multi-view mammograms. This motivates us to leverage the architecture of Vision Transformers to capture long-range relationships of multiple mammograms from the same patient. For this purpose, we employ local Transformer blocks to separately learn patch relationships within a specific view (CC/MLO) of one side (right/left) of mammogram. The outputs from different views and sides are concatenated and fed into global Transformer blocks, to jointly learn patch relationships between two different views of the left and right breasts. To evaluate the proposed model, we retrospectively assembled a dataset involving 949 sets of CC and MLO view mammograms, which include 470 malignant cases and 479 normal or benign cases. We trained and evaluated the model using a five-fold cross-validation method. Without any arduous preprocessing steps (e.g., optimal window cropping, chest wall or pectoral muscle removal, two-view image registration, etc.), our two-view Transformer-based model achieves lesion classification accuracy of 77.0% and area under ROC curve (AUC = 0.814), outperforming state-of-the-art multi-view CNNs by 3.1% and 3%, respectively. Meanwhile, the new two-view model improves mammographic case classification accuracies of two single-view models by 7.4% (CC) and 4.5% (MLO), respectively. The promising results unveil the great potential of using Transformers to develop high-performing computer-aided diagnosis (CADx) schemes of mammography.
Ten Simple Rules for Using Public Data for Your Research
Authors: Oza Vishal , Whitlock Jordan , Wilk Elizabeth , Uno-Antonison Angelina , Wilk Brandon , Gajapathy Manavalan , Howton Timothy , Trull Austyn , Ianov Lara , Worthey Elizabeth , Lasseigne Brittany
Published: June 2022

With an increasing amount of "omics" data available publicly, there is a need for a guide on how to successfully download and use this data. The 10 simple rules for using public data are: 1) use public data in your research, 2) evaluate data for your use case, 3) check data reuse requirements and embargoes, 4) be aware of ethics for data reuse, 5) plan for data storage and compute requirements, 6) know what you are downloading, 7) download programmatically and verify integrity, 8) properly cite data, 9) make data FAIR and share, and 10) make pipelines and code FAIR and share. These rules are intended as a guide for researchers wanting to make use of available data and to increase data reuse and reproducibility.
Coffee Leaf Tea from El Salvador: On-site Production Considering Influences of Processing on Chemical Composition
Authors: Steger Marc C. , Rigling Marina , Blumenthal Patrik , Segatz Valerie , Quintanilla-Belucci Andrès , Beisel Julia M. , Rieke-Zapp Jörg , Schwarz Steffen , Lachenmeier Dirk W. , Zhang Yanyan
Published: June 2022

The production of coffee leaf tea (Coffea arabica) in El Salvador and the influences of processing steps on non-volatile compounds and volatile aroma-active compounds were investigated. The tea was produced according to process steps of conventional tea (Camellia sinensis) with available possibilities on the farm. Influencing factors were the leaf type (old, young, yellow, shoots), processing (blending, cutting, rolling, freezing, steaming), drying (sun drying, oven drying, roasting) and fermentation (wild, yeast, Lactobacillus). Subsequently, the samples were analysed for the maximum levels of caffeine, chlorogenic acid, and epigallocatechin gallate permitted by the European Commission. The caffeine content varied between 0.37 g/100 g dry mass (DM) and 1.33 g/100 g DM, the chlorogenic acid between not detectable and 9.35 g /100 g DM and epigallocatechin gallate could not be detected at all. Furthermore, water content, essential oil, ash content, total polyphenols, total catechins, organic acids, and trigonelline were determined. Gas chromatography—mass spectrometry-olfactometry and calculating of the odour activity values (OAVs) were carried out to determine the main aroma-active compounds, which are β-ionone (honey-like, OAV 132-927), decanal (citrus-like, floral, OAV 14-301), α-ionone (floral, OAV 30-100), (E,Z)-2,6-nonadienal (cucumber-like, OAV 18-256), 2,4-nonadienal (melon-like, OAV 2-18), octanal (fruity, OAV 7-23), (E)-2 nonenal (citrus-like, OAV 1-11), hexanal (grassy, OAV 1-10), and 4-heptenal (green, OAV 1-9).
Strategies for Generating Human Pluripotent Stem Cell- Derived-Organoid Culture for Disease Modelling, Drug Screening, and Regenerative Therapy
Authors: Gania Zakiya , Noorintan Syarifah Tiara , Septiari Ni Putu Diah Pradnya , Fitriany Dhea Sandra , Torizal Fuad Gandhi
Published: June 2022

Human pluripotent stem cells (hPSCs) have become a powerful tool to generate various kinds of cell types comprising the human body. Recently, organoid technology emerged as a platform to build a physiologically relevant tissue-like structure from the PSCs, which provides a more relevant three-dimensional microenvironment to the actual human body than the conventional monolayer culture system for transplantation, disease modeling, and drug development. Although it holds so many advantages, the organoid culture system still has various problems related to culture methods, which became a challenge to get similar physiological properties to their original tissue counterparts. Here, we discuss the current development of organoid culture methods, including the problem that may arise from the currently available culture systems as well as the possible approach to overcoming the current limitation and improving their optimum utilization for translational application purposes.
Cell division controls final fruit size in three apple (Malus x domestica) cultivars
Authors: Karim Siti Khadijah A. , Allan Andrew C. , Schaffer Robert J. , David Karine M.
Published: June 2022

Apple (Malus x domestica) fruit size is dependent on cell division and cell expansion, processes which are subsequently regulated by plant hormones such as auxins, gibberellins, and cytokinins. In this study, we investigated the role of cell division and cell expansion in apple growth and identified which of the two was more deterministic to final fruit size. Three cultivars of different sizes were selected, namely, ‘Twenty Ounce’ (large-sized), ‘Royal Gala’ (medium-sized), and ‘Crabapple’ (small-sized). Gene expression and cell size analyses were conducted over the course of two consecutive seasons. The expression patterns of three classes of genes were markedly similar across all cultivars. Two cell division markers, namely, MdCDKB2;2 and MdANT2, were discovered to be correlatively expressed as both displayed initially high expression levels, which gradually declined from the early to late stages of growth time course. For cell expansion markers, MdEXP3 was upregulated as the cells expanded, while MdARF106 was expressed in both the cell division and expansion stages. Meanwhile, the ripening related gene MdACO1 was expectedly expressed only during the ending stages associated with ripening. Interestingly, the cell measurements taken regularly from each cultivar throughout the same eperimental timespan showed that cell sizes were unaltered and remained constant from initial pollination at the zeroth Days After Pollination (DAP), to ripening at 120 Days After Full Bloom (DAFB).
New Current Oscillator for Electrical Bioimpedance Spectroscopy
Authors: Marcôndes David William Cordeiro , Bertemes-Filho Pedro , Paterno Aleksander Sade
Published: June 2022

Current sources play an essential role in tissue excitation used in bioelectrical impedance spectroscopy. Most investigations use Howland current sources that, despite their practicality and simplified implementation, have operating frequency limitations and dependence on the load impedance due to theirs narrow output impedance, specially at higher frequencies. The objective of this work is to propose model for a robust current-controlled sinusoidal oscillator. The oscillator is based on fully analog electronics, which enables controlling oscillation phase and amplitude by using a voltage reference. The mathematical model is based on Pyragas control application to the classical harmonic oscillator. From the modelling process, it was build an oscillator topology based on second-generation current carriers and on transconductance amplifiers. The reference signal (Fsync) was a sinusoidal voltage source having a frequency of 1MHz and an amplitude of 1Vpp. The oscillator output current synchronized the oscillations’ phase and amplitude with Fsync, regardless of their magnitude before the control signal acted in the circuit at t≈13.5μs. SPICE simulations using ideal components have confirmed the successful operation of the proposed oscillator. This type of oscillator can be implemented in SOIC, then allowing oscillation control interface with logic circuits.
Effect of Short Course on Improving the Cadres’ Knowledge in the Stunting Reducing Context through Home Visits in Yogya-karta, Indonesia
Authors: Siswati Tri , Iskandar Slamet , Pramestuti Nova , Jarohman Jarohman , Rialihanto Muhammad Primiaji , Rubaya Agus Kharmayana , Wiratama Bayu Satria
Published: June 2022

Abstract: Background: Stunting is primarily a public health concern in LMIC. The involvement of Integrated Service Post cadres is one of the strategies to combat stunting in Indonesia. Objective: This study aimed to determine the effect of a short course on cadres knowledge. Method: A single group pre-post test design was conducted in Yogyakarta, Indonesia, from March to May 2022. Thirty cadres were selected based on the following criteria: willingness to participate, the number of stunted children in their Integrated Service Post (Posyandu), and full attendance at short course. The knowledge scores were measured by a structured questionnaire after short course (post-test 1) and 4 weeks later (post-test 2). We apply STATA 16 to calculate the mean difference (MD) using a t-test and Generalized Estimated Equation (GEE). Furthermore, the adequacy of the short course was evaluated with in-depth interviews. Result: On post-tests 1 and 2, cadres' knowledge of IYCF, children growth monitoring (CGM) and children development monitoring (CDM) significantly improved. The GEE analysis showed that a short course significantly improves cadres' knowledge after age control, education, occupation, and years of experience. Conclusion: Short course in-creased their affection, self-efficacy, and confidence, hence, they are capable of assisting children through home visits.
Donating Health Data for Research: Influential Characteristics of German Self-Trackers
Authors: Pilgrim Katharina , Bohnet-Joschko Sabine
Published: June 2022

Health self-tracking is an ongoing trend as software and hardware evolve, making the collection of personal data not only fun for users but also increasingly interesting for public health research. In a quantitative approach we studied German health self-trackers (N=919) for differences in their data disclosure behavior by comparing data showing and sharing behavior among peers and their willingness to donate data to research. In addition, we examined user characteristics that may positively influence willingness to make the self-tracked data available to research and propose a framework for structuring research related to self-measurement. Results show that users' willingness to disclose data as a "donation" more than doubled compared to their "sharing" behavior (willingness to donate= 4.5/10; sharing frequency= 2.09/10). Younger men (up to 34 years), who record their vital signs daily, are less concerned about privacy, regularly donate money, and share their data with third parties because they want to receive feedback, are most likely to donate data to research and are thus a promising target audience for health data donation appeals. The paper adds to qualitative accounts of self-tracking but also engages with discussions around data sharing and privacy.
Optimization of Hue, Brightness, Luminance, and Saturation Parameters for Video Segmentation Based on Evolutionary Algorithms
Authors: Pensiri Fuangfar , Visutsak Porawat
Published: June 2022

Video segmentation is crucial in a variety of practical applications especially in computer visions. Most of recent works in video segmentation are focusing on Deep learning based video segmentation, there are rooms for improvement in respect of the evolutionary algorithms. This paper aims to propose the novel method to video segmentation by using the optimization of segmentation parameters based on ensemble-based random forest and gradient boosting decision tree. The experimental results show Pareto front of segmentation parameters (hue, brightness, luminance, and saturation). Our optimization model yields accuracy: 85% +/-8.85 % (micro average: 85.00 %), average class precision: 84.88%, and average class recall: 85%. We also show the video segmentation results based on our optimization method and compare our results with Kinect-based video segmentation.
Quiste dentígero y la importancia de su detección precoz. reporte de un caso pediátrico
Authors: Benavides-Guzmán Olger Jesús , Pineda Méndez Alejandro , Rodríguez-Cárdenas Yalil Augusto , Aliaga-Del Castillo Arón , Ruíz-Mora Gustavo Armando
Published: June 2022

Los quistes dentígeros son una patología quística común que se desarrolla entre la primera y la tercera década de la vida, y se asocian principalmente con terceros molares mandibulares incluidos o erupcionados, seguidos de caninos superiores y terceros molares superiores. Este tipo de quistes son el resultado de la proliferación del epitelio del esmalte después de su formación, cuya patogenia no está clara. Se han informado pocos de estos quistes en pacientes pediátricos. El siguiente reporte de caso presenta la rara ocurrencia de un quiste dentígero en un niño de 6 años y describe el tratamiento administrado.
Comparison of the efficacies of 1.0 and 1.5 mm silicone tubes for the treatment of nasolacrimal duct obstruction
Authors: Nakamura Jutaro , Kamao Tomoyuki , Mitani Arisa , Mizuki Nobuhisa , Shiraishi Atsushi
Published: June 2022

This retrospective observational study analyzed the postoperative outcomes of bicanalicular intubation using different diameters of tube stents for treating postsaccal nasolacrimal duct obstruction. A total of 130 patients diagnosed with postsaccal obstruction who underwent endoscopic-assisted silicone tube intubation were included in the study. Patients intubated with a 1.5-mm large-diameter tube were designated as the LD group, and those with a 1.0-mm normal-diameter tube were designated as the ND group. The patency rates of the two groups at 1 year after tube removal were compared using the Kaplan–Meier curve and restricted mean survival time (RMST) method with τ = 365 days. Results demonstrated that the recurrence rate after tube removal was significantly lower in the LD group as compared with the ND group (p = 0.001). The patency rates at 1 year after removal in the LD and ND group were 85.7% (95% confidence interval [CI]: 75.4, 91.9) and 73.9% (95% CI: 61.7, 82.8), respectively. When comparing the patency rates by the RMST method at τ = 365 days, the RMST difference, RMST ratio, and RMTL ratio were higher in the LD group at p = 0.045, 0.052, and 0.046, respectively.
Broad fault zones enable deep fluid transport and limit earthquake magnitudes
Authors: Leptokaropoulos Konstantinos , Rychert Catherine , Harmon Nicholas , Schlaphorst David , Grevemeyer Ingo , Kendall John-Michael , Singh Satish
Published: June 2022

Constraining the controlling factors of fault rupture is fundamental to understanding the earthquake cycle. Fluids can influence earthquake locations and magnitudes, although the exact pathways of fluids through the lithosphere are not well-known. Ocean transform faults are an ideal laboratory to study the factors controlling fault ruptures and fluid pathways given their relative simplicity. Here, we analyse seismicity recorded by the Passive Imaging of the Lithosphere-Asthenosphere Boundary (PI-LAB) experiment, centred around the Chain Fracture Zone. We find that earthquakes beneath mapped morphological transpressional features occur deeper than the brittle-ductile transition predicted by simple thermal models but elsewhere occur shallower. These features are characterised by multiple parallel fault segments and step overs, high b-values, gaps in large historical earthquakes, and seismic velocity structures consistent with hydrothermal alteration. This suggests that broader fault damage zones preferentially facilitate fluid transport into the lithosphere. Although this cools the mantle, it also reduces the potential for large earthquakes at punctuated locations (barriers). These barriers divide the transform into asperity segments that are shorter, thereby limiting the earthquake magnitudes in these regions.
The International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY®) at two years: an analysis of 3,082 registered protocols on inplasy.com, platform features, and website statistics
Authors: Canellas João Vitor dos Santos , Ritto Fabio Gamboa , Rodolico Alessandro , Aguglia Eugenio , Fernandes Gustavo Vicentis de Oliveira , Figueredo Carlos Marcelo da Silva , Vettore Mario Vianna
Published: June 2022

Background
INPLASY® is an international platform for registration of systematic review and meta-analysis protocols launched in March 2020. INPLASY® provides an online database where the protocols are maintained as a permanent public record and can be accessed on the website (www.inplasy.com).
Methods
We described the database features and registered information of all records published since the launch of the registry up to March 31st, 2022. Additionally, the website statistics dataset was analysed to explore user experience and promote data transparency.
Results
A total of 3082 records were registered in INPLASY®, and more than 91% of the protocols were published within 24 hours. Most submissions were from China, followed by Portugal, Brazil, Taiwan, and Spain. INPLASY® website received a total of 240,855 page views from 37,647 visitors during the first two years. These accesses were from 139 countries worldwide. Most of the accesses were from China, followed by The United States, Brazil, and Germany. The review status ‘‘completed and published’’ was observed in 323 protocols, and these studies were published in 156 different scientific peer-reviewed journals. The INPLASY® features included: (i) INPLASY® identifier, a unique protocol number; (ii) DOI number, the URL of the protocol linked to a specific DOI; (iii) ORCID update, INPLASY® updates the authors' ORCID page including their protocol automatically; and (iv) search tools, the protocols are freely accessible on www.inplasy.com.
Conclusions
The INPLASY® has several practical and useful features that should be considered when planning the registration of a systematic review protocol. Furthermore, the sharp increase in the number of protocols registered in INPLASY® in the first two years and the database statistics demonstrate that INPLASY® has become an important source of systematic review protocols. Therefore, authors should access INPLASY® before planning a future review study, either to avoid unintended duplication of efforts, or to obtain registration in a timely manner.
Quality of Life Among Type II Diabetes Mellitus Patients at Kamuzu Central Hospital in Lilongwe, Malawi: A Mixed-Method Study
Authors: Chisalunda Alinafe , Ng’ambi Wingston , Tarimo Nesto , Banda Ndaziona Peter Kwanjo , Muula Adamson Sinjani , Kumwenda Johnstone , Nyondo-Mipando Alinane Linda
Published: June 2022

Background
Type II diabetes mellitus (T2DM) significantly impacts quality of life (QoL) yet data on quality of life among these patients in Malawi are lacking. This study was conducted to assess QoL among patients with T2DM.
Methods
A mixed-method cross-section study was conducted at Kamuzu Central Hospital (KCH), Lilongwe, Malawi. A systematic sampling method was used for quantitative data and purposive sampling was used for qualitative data. A modified diabetes quality of life (MDQoL)-17 questionnaire was used for quantitative data while in-depth interviews and diary methods were used for qualitative data. Demographic data were summarized using descriptive statistics and inferential statistics using t-test and ANOVA. Thematic analysis was utilized to analyze qualitative data. Ethical approval was obtained from the College of Medicine Research and Ethics Committee (CoMREC) reference number P.09.20.3122.
Results
A sample of 339 participants (mean age 50.3 ± 15.5) was recruited. Overall, the mean QoL score was moderate (63.91 ± 19.54). Those with tertiary education and those on health insurance had better QoL (QoL 73.8, C.I. 68.56–79.04, p-value 0.005), (QoL 76.71, C.I. 69.22–84.19, p-value 0.005) respectively compared to those with lower education and those without health insurance. Furthermore, absence of comorbidities was associated with having better QoL (QoL 71.18, C.I. 66.69–75.67, p-value < 0.0001). Qualitatively, participants referred to QoL as an absence of disease and leading an independent life. T2DM was associated with patients’ health status, increased stress levels and loss of independence. There were QoL-promoting factors among T2DM patients such as diabetes health talks, having a supportive family and following hospital advice. Inhibiting factors include drug shortages, societal perceptions, sedentary lifestyle, stress, and despising hospital advice.
Conclusions
Overall QoL in patients with T2DM receiving treatment at KCH is moderate. QoL of patients with T2DM is influenced by interrelated factors which requires multidisciplinary team care to optimize the QoL among these patients. Health workers need to adopt a holistic approach when treating patients with T2DM, such as managing comorbidities and including assessment of QoL, behavioral change measures like physical exercises, and a healthy diet. The government and various stakeholders need to promote mandatory national health insurance which improve health status.
Psychological resilience factors and their association with weekly
stressor reactivity during the COVID-19 outbreak in Europe
Authors: Bögemann Sophie , Puhlmann Lara , Wackerhagen Carolin , Zerban Matthias , Riepenhausen Antje , Köber Göran , Yuen Kenneth , Pooseh Shakoor , Marciniak Marta , Reppmann Zala , Uściƚko Aleksandra , Weermeijer Jeroen , Lenferink Dionne , Mituniewicz Julian , Robak Natalia , Donner Nina , Mestdagh Merijn , Verdonck Stijn , Dick Rolf van , Kleim Birgit , Lieb Klaus , Leeuwen Judith van , Kobylinska Dorota , Myin-Germeys Inez , Walter Henrik , Tüscher Oliver , Hermans Erno , Veer Ilya , Kalisch Raffael
Published: June 2022

Recently, cross-sectional relationships between psycho-social resilience factors (RFs) and resilience, operationalized as an outcome of low reactivity of mental health to stressor exposure (low ‘stressor reactivity’) during the first wave of the COVID-19 pandemic, were reported. Extending these findings, we here examine prospective relationships and weekly dynamics between the same RFs and stressor reactivity in a longitudinal sample during the aftermath of the first wave in several European countries. Over five weeks of app-based assessments, participants weekly reported stressor exposure, mental health problems, RFs, and demographic data, in one of six different languages. As (partly) preregistered, hypotheses were tested cross-sectionally at baseline (N=558) and longitudinally (N=200), using mixed effects models and mediation analyses. RFs at baseline, including positive appraisal style, optimism, self-efficacy, perceived good stress recovery, and perceived social support, were negatively associated with stressor reactivity (SR) scores, not only cross-sectionally (baseline SR scores) but also prospectively (average SR scores across subsequent weeks). In both analyses, positive appraisal style mediated the effects of perceived social support on SR. In the analyses of weekly RF-SR dynamics, RFs positive appraisal (of stressors generally and specifically of the Corona crisis) and general self-efficacy were negatively associated with SR in a contemporaneous, but not lagged fashion. We identify psychological RFs which prospectively predict resilience and co-fluctuate with weekly stressor reactivity within individuals. The prospective results endorse that the previously reported RF-SR associations do not exclusively reflect mood-congruency or other temporal bias effects. We further confirm an important role for positive appraisal in resilience.
A touchless user interface based on a near-infrared sensitive transparent optical imager using printed Cu grid electrodes.
Authors: Kamijo Takeshi , Breemen Albert van , Ma Xiao , Shanmugam Santhosh , Bel Thijs , de Haas Gerard , Peeters Bart , Petre Razvan , Tordera Daniel , Verbeek Roy , Akkerman Hylke , Hagelsieb Luis , de Roose Florian , Lieberman Itai , Janssen René , Meulenkamp Eric A. , Kronemeijer Auke , Gelinck Gerwin
Published: June 2022

Touchless technology based on user interaction modes such as voice or gestures is paving the way for tomorrow’s digital ecosystems, accelerated by hygiene requirements resulting from the COVID-19 pandemic. Gesture-based touchless user interfaces typically use near-infrared (NIR) cameras. The applicability of these systems is hampered by their limitations in field of view and their calibration requirements for high accuracy. Here, we show a novel touchless user interface based on a large-area visually transparent NIR-sensitive 16 × 16 organic photodetector (OPD) array that can be used on top of a display as a touchless user interface. Optical transparency is realized by implementing a printed copper (Cu) grid as a bottom transparent conductive electrode (TCE) and an array of patterned OPD subpixels. Electro-optical modelling enabled an optimal image sensor design that resulted in a high photodetectivity of ca. 1012 Jones at 850 nm and high visible-light transmittance of 70%. We demonstrate that our imager can be used as a penlight- and gesture controlled touchless user interface when combined with a commercial display.
A Posture Detection Method for Augmented Reality Aided Assembly Based on YOLO-6D
Authors: Zhang Liping , XU Feng , Liu Yu , Zhang Dan , Gui Liang , Zuo Dunwen
Published: June 2022

The assembly of small batch electrical and mechanical products still relies on manual operation, with the problems of high rechecking time and low assembly efficiency and quality. The augmented reality technology can be used to assist assembly to improve efficiency. In view of the high professionalism, labor and time cost for the traditional posture detection method, a posture detection method is proposed to match the assembly posture by pre-calibrating the assembly posture template. YOLO-6D deep learning network is brought in to increase the accuracy of virtual information tracking registration. And the detection from both translation and rotation perspectives is designed to enhance the adaptability to different assembly tasks. For the generation of training datasets, a weighted sampling method based on part features is proposed to optimize the accuracy of position estimation with the limited training samples. Taking the assembly process of typical electronic products as an example, the developed augmented reality aided assembly system is used to boost the assembly efficiency of assembly operators. It is illustrated that the proposed positional detection method is effective in registering virtual assembly guidance information in real scenarios and can be applied to augmented reality assembly guidance of products.