bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral health related quality of life and satisfaction with dental condition of school age children with dental pain in Ibadan, Nigeria.
Authors: Lawal Folake , Oke Gbemisola Aderemi
Published: December 2019

Background Pain of dental origin is a major reason why school age children seek dental care in low resource settings but how it affects their oral health related quality of life and satisfaction with dental condition remains under researched. The aim of the study was to determine the impact of dental pain on oral health related quality of life as well as its association with satisfaction with dental condition of school age children in Ibadan, Nigeria.Methods This cross-sectional study was conducted among 1006 pupils aged 9-12 years who attended randomly selected primary schools in Ibadan, Nigeria. An interviewer administered questionnaire, Child–Oral Impact on Daily Performances inventory (C-OIDP) in addition to oral examination was used to obtain data. Analysis was done with SPSS version 23 and p value < 0.05 was considered significant.Results The prevalence of self-reported dental pain was 10.2%. The mean C-OIDP score was 2.6 (±7.2) overall and 9.8 (±12.4) for pupils with pain. About 68.9% of pupils with pain reported an impact on quality of life compared to 15.6% of those without dental pain (p < 0.001). Self-reported dental pain affected social, psychological and physical activities (p < 0.001). More children with dental pain (53.4%) were dissatisfied with their dental condition compared to those (12.8%) without dental pain (p < 0.001). Dental pain correlated with dissatisfaction with dental condition (rs = 0.32, p < 0.001). Among children with dental pain; those who were dissatisfied with their dental condition were more likely to report impairment in eating and enjoying food (OR=2.2, CI =1.1 - 4.1, p = 0.018) as well as in maintaining social contact (OR =3.1, CI =1.1 -9.1, p = 0.033).Conclusion Self-reported dental pain significantly impacted on all the domains of quality of life of the pupils and correlated positively with dissatisfaction with dental condition. Eating and enjoying food as well as maintaining social contact were significant predictors of dissatisfaction with dental condition among children with dental pain.
Functional analyses of chitinolytic enzymes in the formation of calcite prisms inPinctada fucata
Authors: Kintsu Hiroyuki , Pérez-Huerta Alberto , Ohtsuka Shigeru , Okumura Taiga , Ifuku Shinsuke , Nagata Koji , Kogure Toshihiro , Suzuki Michio
Published: December 2019

Background: The mollusk shells present distinctive microstructures that are formed by small amounts of organic matrices controlling the crystal growth of calcium carbonate. These microstructures show superior mechanical properties such as strength or flexibility. The shell of Pinctada fucata has the prismatic layer consisting of prisms of single calcite crystals. These crystals contain small-angle grain boundaries caused by a dense intracrystalline organic matrix network to improve mechanical strength. Previously, we identified chitin and chitinolytic enzymes as components of this intracrystalline organic matrix. In this study, we analyzed the function of those organic matrices in calcium carbonate crystallization by in vitro and in vivo experiments.Results: We analyzed calcites synthesized in chitin gel with or without chitinolytic enzymes by using transmission electron microscope (TEM) and atom probe tomography (APT). TEM observations showed that grain boundary was more induced as concentration of chitinolytic enzymes increased and thus, chitin became thinner. In an optimal concentration of chitinolytic enzymes, small-angle grain boundaries were observed. APT analysis showed that ion clusters derived from chitin were detected. In order to clarify the importance of chitinolytic enzymes on the formation of the prismatic layer in vivo , we performed the experiment in which chitinase inhibitor was injected into a living Pinctada fucata and then analyzed the change of mechanical properties of the prismatic layer. The hardness and elastic modulus increased after injection of chitinase inhibitor. Electron back scattered diffraction (EBSD) mapping data showed that the spread of crystal orientations in whole single crystal also increased by the effect of inhibitor injections.Conclusion: Our results suggested that chitinolytic enzymes may function cooperatively with chitin to regulate the crystal growth and mechanical properties of the prismatic layer, and chitinolytic enzymes are essential for the formation of the normal prismatic layer of P. fucata.
Tridax Procumbens Amines Have A Potential To Synthesize Silver Nanoparticles
Authors: Ondari Erick Nyakundi , Omwenga Samuel Gichaba , Madanagopal Nalini
Published: December 2019

Our previous findings showed that amines from Tridax procumbens (Family: Asteraceae) were responsible for the synthesis of silver nanoparticles. T. procumbens is a weed plant with rich source of medicinal compounds. In the current work, we studied the initial characterization of bioactive compounds by LC-MS, an essential tool for the characterization and identification of low molecular compounds. Further the isolated compound was investigated for silver nanoparticle synthesis. The leaf extracts examined revealed many novel amine derivative compounds reported for the first time mainly belonging to the group of free amines: n-Pentylhydrazine hydrochloride, 2-Nitrobenzenesulfonyl chloride, 1,7-Dichlorooctamethyltetrasiloxane, 5-Chloro-1,2,4-trihydroxybenzene, 3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine and 2-(Diphenylphosphino) ethyltriethoxysilane and conjugated amines: 5-Methoxy-diisopropyltryptamine, 4-Chlorophenoxyacetic acid, Diphenhydramine, Erucamide, n(4-((2-(2,5-dimethoxybenzylidene)hydrazino)carbonyl)ph)-4-me-benzenesulfonamide and 1,3,5-Trithia-2,4,6-tristannacyclohexane, 2,2,4,4,6,6-hexamethyl. Characterization by UV-Vis spectra, XRD, EDX and TEM revealed well separated spherical shaped AgNPs size ranging 8-50 nm. These findings suggest that further work could be extended to isolate and elucidate the structures of the identified molecules using powerful instruments such as HPLC-MS, HPLC-NMR and high resolution-MS (HR-MS). Further biotechnological approaches towards synthesis of novel metals will be enhanced to promote green chemistry technology adoption for the synthesis of nanoparticles.
Early alterations of circulating immune cell counts in severe trauma patients are related to later occurrence of nosocomial infection, sepsis and mortality
Authors: Dong Xijie , Wang Chuntao , Liu Xinghua , Bai Xiangjun , Li Zhanfei
Published: December 2019

Background: Severe trauma leads to extensive disturbances of the innate and adaptive arms of the immune system, which in turn may affect the prognosis. The main objective of this study was to investigate the relationship between the alterations of circulating immune cell counts in the early stage of severe trauma and the later occurrence of nosocomial infection, sepsis and mortality. Methods: This was a retrospective study of 876 patients with an Injury Severity Score (ISS) ≥ 16. Demographic data, the absolute counts of neutrophil, lymphocyte and monocyte (ANC, ALC and AMC) on days 1, 3, and 7 (D1, D3, and D7) after trauma, and whether nosocomial infection, sepsis or death occurred within 60 days were recorded. Ratios were calculated between immune cell counts of each two time points, namely day 3/day 1 (D3/D1) and day 7/day 3 (D7/D3). Patients were grouped based on ISS and the occurrence of nosocomial infection, sepsis or death. Comparative studies were conducted between each two groups. Univariate and multivariate logistic regression analysis were used to identify variables related to the risk of nosocomial infection, sepsis, and mortality. Receiver operating characteristic (ROC) curve was plotted to assess the predictive value of various risk factors. Results: More severe trauma leads to more pronounced increase in ANC and more slowly recovery of ALC. In patients with subsequent nosocomial infection and sepsis, ANC was higher and ALC recovery was slower than those without nosocomial infection and sepsis within 7 days. In non-survivors, ALC had not recovered and AMC (D3) and AMC (D7) was lower than survivors within 7 days. ALC (D3) and ALC (D3/D1) are independent risk factors for nosocomial infection and sepsis. ALC (D3), ALC (D3/D1), ALC (D7) and AMC (D7) are independent risk factors for death. The combination of ALC (D3/D1) and ALC (D3) had a good predictive value for the occurrence of nosocomial infection, sepsis, and mortality. Conclusions: More severe trauma causes more intense interference to circulating immunocyte counts. Worse alterations in circulating immunocyte counts within 7 days may increase the risk of subsequent nosocomial infection, sepsis and mortality.
Duration of acute kidney injury, 90-day mortality, and chronic kidney disease progression in very elderly patients
Authors: Li Qinglin , Pan Liang , Mao Zhi , Kang Hongjun , Zhou Feihu
Published: December 2019

Background: This study evaluated the prognostic impact of AKI duration on 90-day mortality and new-onset chronic kidney disease (CKD) progression in very elderly patients. Methods: We retrospectively enrolled very elderly patients (≥75 years) with normal RF from the hospital information system of the National Clinical Research Center for Geriatric Diseases of Chinese PLA General Hospital January 1, 2007 and December 31, 2018. AKI was diagnosed using the Kidney Disease: Improving Global Outcomes criteria. AKI patients were divided into T-AKI and P-AKI groups based on whether serum creatinine level returned to baseline within 48 h post-AKI. Results: In total, 760 geriatric patients developed AKI, and 693 were suitable for the final evaluation. Among them, 62 (8.9%) patients had T-AKI (1–2 days), 104 (15.0%) had short-duration AKI (3–4 days), 140 (20.2%) had medium-duration AKI (5–7 days), and 387 (55.8%) had long-duration AKI (>7 days). In total, 209 (30.2%) of 693 patients died within 90 days, including 5 (8.1%) with T-AKI and 204 (32.3%) with P-AKI. Of the 484 survivors with AKI, 122 (25.2%) developed CKD. After adjusting for multiple covariates, duration of AKI (3–4 days: hazard ratio [HR] = 2.512; 95% confidence interval [CI]: 1.021–6.181; 5–7 days: HR = 3.154; 95% CI: 1.250–7.960; >7 days: HR = 6.212; 95% CI: 2.383–16.192;), more advanced AKI stages (stage 2: HR = 7.365; 95% CI: 4.114–13.183; stage 3: HR = 28.414; 95% CI: 16.360–49.350); and low body mass index (HR = 0.910; 95% CI: 0.870–0.953) were significantly associated with a higher 90-day mortality and longer AKI duration (3–4 days: odds ratio [OR] = 0.982; 95% CI: 0.247–3.900; 5–7 days: HR = 1.322; 95% CI: 0.381–4.592; > 7days: HR = 7.007; 95% CI: 2.417–20.311), and baseline eGFR (OR = 0.928; 95% CI: 0.901–0.956) was significantly associated with new-onset CKD of the survivors. Conclusion: AKI duration is a useful parameter to predict of worse clinical outcomes in very elderly patients, emphasizing the importance of identifying an appropriate treatment window for early intervention.
Circulating rather than alveolar extracellular DNA levels predict outcomes in influenza: a cohort study
Authors: Zhang Nannan , Zhu Liuluan , Zhang Yue , Zhou Chun , Song Rui , Yang Xiaoyu , Huang Linna , Xiong Shuyu , Huang Xu , Xu Fei , Wang Yajie , Wan Gang , Chen Zhihai , Li Ang , Zhan Qingyuan , Zeng Hui
Published: December 2019

Background: We have reported that high levels of circulating neutrophil extracellular traps (NETs) are associated with a poor prognosis in patients with severe influenza A infection. It remains unclear whether NETs in the bronchoalveolar lavage fluid (BALF) are a superior biomarker for predicting clinical outcomes in influenza.Methods: One hundred eighteen patients who were diagnosed with H1N1 influenza in 2017-2018 were recruited. NETs were assessed in plasma and BALF samples by quantifying cell-free DNA (cfDNA) and protein-DNA complexes. Predictions of severe illness and 60-day mortality were analyzed with receiver operating characteristic curves.Results: The NET levels were significantly elevated in the BALF and contributed to the pathological injury of lungs, yet it was not associated with disease severity or mortality in patients severely infected with H1N1. Plasma NET levels were significantly increased in the patients with severe influenza and positively correlated with the oxygen index and sequential organ failure assessment scores. High levels of plasma cfDNA (> 286.6 ng/ml) or histone-bound DNA (> 9.4 ng/ml) on the day of admission predicted severe influenza, and even higher levels of cfDNA (> 306.3 ng/ml) or histone-bound DNA (> 23.1 ng/ml) predicted fatal outcomes in severely ill patients.Conclusions: Alveolar NETs contribute to lung damage but do not correlate with outcomes in patients with severe H1N1 infection. Plasma cfDNA and histone-bound DNA represent early predictive biomarkers for the prognosis of influenza.
Astrocyte-like glia-specific gene deathstar is crucial for normal development, adult locomotion and lifespan of male Drosophila
Authors: Najafi Hadi , Wong Kyle , Kim Woo Jae
Published: December 2019

Background: Drosophila melanogaster is a proper model organism for studying the development and function of the nervous system. The Drosophila nervous system consists of distinct cell types with significant homologies to various cell types of more advanced organisms, including human. Among all cell types of the nervous system, astrocyte-like glia (ALG) have conserved functions to mammals and are essential for normal physiology and behaviours of the fly.Results: In this study, we exploited the gene expression profile of single cells in Drosophila optic lobe to identify the genes with specific expression pattern in each cell type. Through a bioinformatical analysis of the data, a novel ALG-specific gene (here assigned as deathstar) was identified. Immunostaining of deathstar in the central nervous system (CNS) showed its presence in specific regions of Drosophila ventral nerve cord, which previously has been characterized as ALG cells. Consistent with the bioinformatical analysis, deathstar-related signals were overlapped with the signals of the previously-reported ALG marker, Eaat1, supporting its specific expression in ALG cells. At the physiological level, RNAi-mediated suppression of deathstar gene impeded the normal development of male flies without any effects on females. Cell type-specific expression of deathstar RNAi showed that deathstar gene affects locomotion behaviour and lifespan of D. melanogaster, in an ALG-specific manner.Conclusions: Taken together, we showed that bioinformatical analysis of a previously reported expression data of Drosophila optic lobe successfully predicted the ALG-specific expression pattern of deathstar gene. Moreover, it was consistent with the ALG-specific effects of this gene on locomotion and lifespan of D. melanogaster, in vivo.
DHFR silencing effects on biological behaviour of ovarian carcinoma cells in vitro
Authors: Li Zhuang , Yang Zhijun , Zhang Wei , Niu Qian , Li Li
Published: December 2019

Background: Dyhidrofolate reductase (DHFR) is involved in the DNA synthesis and is expressed highly in platinum resistant ovarian carcinoma tissue . The relationship between DHFR gene and platinum drug resistance in ovarian carcinoma (OC) is still unclear. Methods: To design targeting hairpin siRNA of DHFR gene, and constructed lentiviral vector carrying DHFR gene, then though flow cytometry、high performance liquid chromatography and electron microscope, DHFR gene expression was down-regulating to investigate the biological behaviour of DHFR in OC. Results: DHFR mRNA expression in ovarian carcinoma was higher than normal ovarian tissues, in patients with omentum metastasis was lower than that in patients without omentum metastasis, in patients with CR for treatment was lower than that of patients with SD or PD or PR, cisplatin-sensitive patients was lower than that in cisplatin-multidrug resistant cases. The median survival period of patients with DHFR mRNA expression lower than 0.331(Youden index) was 16.4 months, but of that higher than 0.331 was 44.5 months. COX multivariate analysis showed that DHFR mRNA expression was a dependent prognostic factor. The apoptosis rate of DHFR-pGCSIL-SKOV3 was obvious higher than pGCSIL-SKOV3 and SKOV3 cells at 24h and 48h(P＜0.05). GO/G1 stage rate of three groups at 24h、48h and 72h were decreasing but the G2/M and S stage rates were raising. The cells in the cisplatin concentration (2.5、5.0μg/mL)at 24h and 48h,the intracellular cisplatin content of DHFR-pGCSIL-SKOV3 cell were significantly higher than pGCSIL-SKOV3 and SKOV3 cells. The microfilament increased and gathered together, mitochondrial structure also change obviously under no drug. But there were rarely microfilament in three group cells induced by IC50 cisplatin concentration(4.4、5.5、4.9µg/ml)at 24 and 48 h, while at 72 h, there are obvious increase and inordinate microfilament. Conclusion: DHFR silencing inhibits cell growth and cisplatin resistance, there were certain contact between resistance increases with microfilament gathered and the change of the mitochondria.The results laid the foundation for us to investigate the molecular mechanisms of multidrug-resistance in tumor.
iTRAQ-based Comparative Proteomic Analysis of Flag Leaves of Two Wheat (Triticum aestivum L.) Genotypes Differing in Waterlogging Tolerance at Anthesis
Authors: Wei Mingmei , Li LiuLong , Xie Ke , Yang Rui , Wang Xiaoyan , Sha Aihua
Published: December 2019

Background : Waterlogging is one of the major abiotic stresses limiting wheat product. Plants can adapt to waterlogging with changes in morphology, anatomy, and metabolism. Many genes and proteins play critical roles in adaptation to waterlogging. Results : the iTRAQ-based proteomic strategy was applied to identify the waterlogging-responsive proteins in wheat. A total of 7,710 proteins were identified in two wheat varieties, XM55 (waterlogging-tolerant) and YM158 (waterlogging-sensitive), at anthesis under waterlogging or not. Sixteen proteins were differentially accumulated between XM55 and YM158 under waterlogging with cultivar specificity. Of these, 11 proteins were up-regulated and 5 proteins were down-regulated. The up-regulated proteins included Fe-S cluster assembly factor, heat shock cognate 70, GTP-binding protein SAR1A-like, and CBS domain-containing protein. The down-regulated proteins contained photosystem II reaction center protein H, carotenoid 9,10 (9',10')-cleavage dioxygenase-like, psbP-like protein 1, and mitochondrial ATPase inhibitor. In addition, 9 proteins were responsive to waterlogging with non-cultivar specificity. These proteins included 3-isopropylmalate dehydratase large subunit, solanesyl-diphosphate synthase 2, DEAD-box ATP-dependent RNA helicase 3, and 3 predicted or uncharacterized proteins. Conclusion s: This study revealed that the proteins were differential accumulated between the two contrast waterlogging wheat varieties in response to waterlogging, which provide valuable insights into wheat response to waterlogging stress. These differentially accumulated proteins might be applied to develop waterlogging tolerant wheat in further breeding programs.
INNOVATIVE DECISIONS TO IMPROVE FOOD QUALITY AND SAFETY
Authors: Eveleva V. V. , Cherpalova T. M.
Published: December 2019

The scope of the project consisted in research-based development of new complex food additives from lactic acid and its derivatives for enhancing microbiological safety and shelf life extension of healthy food products. The object of research included: trial samples of complex food additives from lactic acids and its derivatives. The samples were obtained chemically using the following basic components: food grade lactic acid with 79.6% base substance mass fraction; acetic acid with 99.8% base substance mass fraction; propionic acid with 99.6% base substance mass fraction; neutralizing agents for synthesis of salts of the acids used, and propylene glycol with 99.8% base substance mass fraction. The optimal balance of the ingredients in the formula of the additive delivers the optimal level of true acidity combined with antimicrobial and antioxidant effect, and enhances organoleptical performance and process parameters of food products. This complex food additive containing lactate and acetate features high counter-regulatory effect on testing cultures of pathogenic organisms of rope spoilage of wheat bread and can be used for production of non-perishable products. The use of complex food additive in the production of dressed fish preserves activates biochemical processes related to fish maturation and delivers improved product quality and extended shelf life.
EQUIPMENT AND SCIENTIFIC STUDIES OF EXPERIMENTAL DATA ON STORAGE OF WHEAT GRAIN
Authors: Markov Yu. F. , Buriak A. N. , Eresko L. G.
Published: December 2019

A complex of technical solutions is presented which makes it possible to study the influence of external factors on changes in the indicator of fat acidity value (FAV) and a range of other parameters characterizing the quality of preservation of long-term stored wheat grains in South Russia. Storage conditions (natural climatic, model) and also the effect of dust suppression treatment of grain by oil glazing that is carried out in some grain terminals in the South of Russia were taken as controlled external factors. New data has been obtained on changes in parameters of food suitability of the wheat grains during storage under model conditions with varying degrees of severity of climatic conditions in South Russia. After 6 months of storage the most considerable changes in FAV value were found for 4th class of wheat stored in natural climatic conditions with intensive insolation, the increase was 1.7 mg KOH/1 g of fat (from 7.3 mg KOH/1 g of fat up to 9.0 mg KOH/ 1g of fat). Minimum changes in the same parameter for the same storage period were observed for the wheat of the 3rd class stored in a thermostat at a stable high temperature of 35 ºС (from 11.6 mg KOH/1 g of fat to 11.5 mg KOH/1 g of fat). For wheat of the 4th class, the changes were 0.7 mg KOH/1 g of fat (from 7.8 mg KOH/1 g fat to 8.5 mg KOH/1 g of fat). Analyzes of stored wheat grains subjected to dust suppression by the oil glazing showed similar results, which allows us to state the absence of a significant effect of oil glazing on changes in wheat properties during its storage.

Based on the results of the experimental analysis and a generalization of the data obtained an assumption was made on the possible reasons for the lack of pronounced trends in the data for the expected increase of FAV value in food suitability of the wheat grain when it is stored under typical model conditions of South Russia. The likely reason for this is the corresponding moisture state of grain, the water activity of grain was about 0.45. Such a low value was due, in particular, to the fact that samples of model-stored grain had a limited volume and do not reproduce the mass transfer processes that involve deep layers of the grain mass (because of the mass absence), which takes place during storage of grain in an industrial environment. The tools were proposed for the operational monitoring of the moisture state of wheat grain during storage. Moreover, a plan has been developed to expand the field of modelling storage processes in terms of varying the moisture state of the stored wheat grain samples with an assessment of the influence of moisture state on the dynamics of changes in the parameters to be controlled.
DEVELOPING THE METHODS OF FOOD PRESERVATIVES EXTRACTION FROM COMPLEX MATRICES FOR BIOASSAY PURPOSE
Authors: Samoilov A. V. , Suraeva N. M. , Koptsev S. V. , Glazkov S. V.
Published: December 2019

The presence of food additives in food products may be associated with the risk of their toxic effects on human body. Therefore, the study of approaches to testing their safety seems to be a particularly urgent task. The aim of this study was to determine the conditions for extracting food preservatives from the samples of preserved pureed vegetables for further bioassay of the extract obtained in the Allium test. Onion roots were used as a test object in this method. Two extraction methods of benzoic and sorbic acids added to pureed vegetables have been developed. Distilled water and acetone were used as extracting solutions. The extraction efficiency was evaluated on Shimadzu Prominence LC-20 liquid chromatograph (Japan) in the ultraviolet range, wavelength 235 nm (benzoic acid), 285 nm (sorbic acid). According to the results of studies using both water and acetone as extractants, the degree of preservatives extraction was approximately the same and quite high. In the quantitative calculation of the preservatives content in pureed vegetables, the value of the correction factor was 0.8. However, due to certain production characteristics of this product, i. e. the stage of cauliflower homogenization, obtaining an extract with acetone seems to be more acceptable for the Allium test conditions.
Formation of the strategic sustainability management system for the organization's innovation activities
Authors: Grigorieva S. V.
Published: December 2019

The article deals with the main provisions of the formation of the management system of strategic sustainability of the innovative activity of the organization. The structure and content of the management system of strategic sustainability of innovative activity of the organization are proposed. The management system of strategic sustainability of innovation development of the organization is expressed in the management of effective use of strategic resources of the organization, management of the results of strategic sustainability taking into account the risks of economic activity and innovation management to improve the level of strategic sustainability.
Analysis and prospects of development of Russian nuclear energy
Authors: Tupchienko V. A. , Imanova H. G.
Published: December 2019

The article deals with the prospects of nuclear power development in Russia. The paper analyzes the key document in this area - «Energy strategy of Russia for the period up to 2030». It was found that today Russia has formed for itself the key aspects of the development of nuclear energy, which is due not only to the need of the population and enterprises in energy, but also the need of the country to ensure its own energy security and economic stability.
Development of regional industrial tourism and the organization of tourist routes in enterprises
Authors: Usova A. V. , Kovshikova G. A.
Published: December 2019

Industrial tourism is a promising direction of development of the tourism industry. The article analyzes the concept of «industrial tourism», authors made the list of enterprises that can be included in the industry tour on the example of the Vologda region, recommendations for production companies on the organization of industrial tourism in enterprises are given.
The development of the concept of cluster and network organization of socio-economic space of the territories
Authors: Feraru G. S. , Kiselev D. N.
Published: December 2019

The paper describes general theoretical principles, revealing the peculiarities of development of the concept of cluster and network organization of socio-economic space of the territories and reflecting the author's vision of the benefits of network interactions in comparison with a hierarchical mechanism in the structure of the economy, as well as the results of the comparative analysis of cluster and cluster-network models of the socio-economic space of the territories.
Actual problems of organization of separate collection and recycling of solid waste in the Moscow region
Authors: Fedotov A. V.
Published: December 2019

The article deals with problems of separate collection and recycling of solid waste in the Moscow region. Analyses the results of the survey conducted among area residents on issues under study. Compares the Organization of street cleaning, collecting, transporting and recycling of domestic waste in Moscow region. Examines the activities of the individual companies involved in the collection and recycling of household waste. Makes recommendations for improving the organization of separate collection and disposal of solid waste.
Analysis of the security system in the field of Internet - payments using payment cards
Authors: Botasheva L. H. , Ryzhenkova N. E. , Tukhbatulina M. A.
Published: December 2019

The main ways to protect money held on bank payment cards when making Internet payment were analyzed. A number of certificates and licenses were also analyzed, providing guarantees to customers of sites from which purchases using payment cards are made; an assessment of the effectiveness of existing methods has been made and new ways of implementing bank card security in the process of Internet payments using payment cards have been proposed.
Reculiarities of formation of innovative infrastructure of the regional industrial complex
Authors: Veselovsky M. Ya. , Ignatova O. V. , Aleksakhina V. G.
Published: December 2019

The article analyzes the features of the formation of innovative infrastructure of the regional industrial complex, identifies the main constraints to the development and functioning of innovative infrastructure in the regions, proposes measures to address existing problems.
Simulation and optimization tools in outsourcing management tasks
Authors: Kulikov A. I.
Published: December 2019

The article discusses the main issues to assess the feasibility of the transition to outsourcing enterprises. Particular attention is paid to the methodological modeling tools designed to help enterprises in making decisions about the possibility of switching to outsourcing.
Information base of statistical study of investment flows in the regional primary real estate market
Authors: Dianov D. V. , Limonov S. V.
Published: December 2019

The scientific article covers the problematic issues of implementation of statistical observation in the organization of information flows on the state, structure, dynamic development, patterns and trends of regional primary real estate markets. The defining features of the classification of objects and operations, the main blocks of statistical indicators of circulation of objects created in the region, in the primary real estate market, identified and formulated features of accounting and valuation of objects not attributable to the housing stock, land and construction in progress. Since we are talking about objects of real estate, rights of ownership of which are transferred for the first time, it covers the issues of statistical monitoring of the regional investment in the newly created objects of the gross accumulation of fixed assets and the land Fund.
Influence of life cycle stages of high-tech engineering enterprises on personnel management strategies
Authors: Veselovsky M. Y. , Abrashkina E. M.
Published: December 2019

In scientific research provides a rationale for the influence of the life cycle stages of high-tech engineering enterprises on personnel management strategies. It was proved that most of these enterprises are at the stages of stable operation, growth or crisis conditions. Their main intellectual and production reserve was formed in the years of the planned economy. Based on the analysis of management approaches at these stages of the life cycle of organizations, tools have been proposed for improving the personnel management system. The main ones should be the strengthening of social partnership, change in corporate culture and orientation towards optimization of personnel and expenses for them.
Cognitive models for creating information systems for managing the costs of the industrial sector of the economy
Authors: Ivanova O. E.
Published: December 2019

The article notes the tasks associated with cognitive models of domain management. The patterns of development of the industrial sector of the economy are highlighted and the cost component is designated as a key composition of the development of production. With the use of the decision system “IGLA”, the connectedness of the system to the concept and the concept to the system on the basis of the constructed cognitive map was determined, which served as the basis for constructing development scenarios on the example of textile production.
Social challenges based on the digital transformation of high-tech enterprises
Authors: Koblov S. V.
Published: December 2019

The article presents the essence of the digital transformation of enterprises, shows the potential social challenges that accompany the introduction of the digital economy. For enterprises of high-tech industries, due to their high intellectual intensity, foreseeing the potential risks of social character is the most important. The necessity of developing a mechanism for managing the social state of a collective in the process of digital transformation of enterprises is substantiated.
Ensuring the financial security of diversified business entities
Authors: Kudryashova N. V. , Elagin V. I.
Published: December 2019

The article deals with issues related to the development of market-based methods for increasing the stock of financial sustainability of regional consumer societies located in rural areas. The result of the work is a number of methodological and practical developments to ensure the financial security of organizations that are used in the preparation of laws and regulatory documents at the level of a constituent entity of the Russian Federation. Also they are successfully implemented into three district consumer societies.
The role of vertically integrated structures in the development of the manufacturing sector of the economy
Authors: Topoleva T. N.
Published: December 2019

The article studies the essence and the main reasons of vertical integration process in Russian manufacturing sector. We have noted the economic and organizational and management advantages of integrated enterprises, taking into account the international experience of large highly-integrated corporations functioning - growth drivers of economy of different countries all over the world. The article considers historical stages of integrated structures forming in Russia, methodic means of analysis and assessment of integrated economy level, model vertically integrated structures. We have considered a complex of the state support measures and stimulation of enterprises to the interaction within the framework of integrated unions.
The sustainability of cluster business structures in a crisis
Authors: Khatsenko E. S.
Published: December 2019

The article is devoted to the problems and prospects for the development of the stability of cluster associations. The typology of factors influencing the entrepreneurial shell is considered. The tools for analyzing and identifying crisis signs in the early stages are defined. Considered support measures through the formation of a regional center for diagnosis and financial recovery.
Innovation in Russia: regional and industrial aspects
Authors: Khristoforova I. V. , Idilov I. I. , Abrashkin M. S.
Published: December 2019

The article is of an analytical and analytical nature and is based on information prepared in the course of desk research. Secondary data from the Internet is used, including from the website of the Federal State Statistics Service. The review made it possible to consider the current state of affairs in the field of innovation management in the Russian Federation, to make comparisons on individual indicators in territorial and sectoral contexts. The main problems and possible ways of development of innovative activity are revealed; the role of the state in the development of innovative policy of the country, regions, specific industries and enterprises is shown.
The development of the system of accounting, control, analytical support, management tactics and development strategy of a large company оf holding type
Authors: Bondarenko A. A.
Published: December 2019

This article is based on the definition of key positions proposed by the author of vertical-horizontal operation of the Department coordinating JSC «RZD», combining the functions of accounting, control, analytical support, management tactics and development strategy of a large company of holding type. This article discusses the controversial aspects of the selection system of accounting and control and analytical support of management strategy and tactics of development of railway transport by all information flows in one using the automation of accounting, control, management processes, implementation of electronic document management, electronic financial and management reporting. The conclusions drawn are that the decision is strategically important and essential tasks of innovative development of JSC «RZD», requires improvement of their accounting information support, which in turn is impossible without development of methods of management costs, taking into account branch specificity of formation of the cost of rail transportation. The author offers methodicalsecurity projects (Development of KPI; financial Management and assurance Strategy development; Business planning; Operation of the Treasury; Cost management, etc.) that can greatly increase the informational efficiency of calculation.
Theoretical aspects on the essence and role of territories with special economic status in ensuring the spatial development of the regions of Russia
Authors: Akhmeduev A. Sh. , Medzhidov Z. U.
Published: December 2019

Modernization of the Russian economy, connected with the transition to innovative development, led to the transfer of strategic management of the economy to the level of regions. There has been increased interest in the area of economic research, such as the study of the spatial development of the region 's economy through the introduction of various instruments to stimulate the socio-economic development of the regions, which include territories with special economic status. Despite the availability of a sufficient number of publications on the study of the spatial development of regions of Russia and territories with special economic status, certain terminological aspects of this issue are still not sufficiently disclosed and clarified. The article describes the theoretical approaches of some domestic authors on this issue. The author 's vision of the concepts of «spatial socio-economic development of the region», territory with special economic status, «territorial cluster» is proposed.
The state and development of small and medium-sized businesses in the Kemerovo region
Authors: Kozlova Yu. V.
Published: December 2019

The article considers the state and development of small and medium entrepreneurships in the Kemerovo region. In addition, the number of small and medium-sized businesses, their annual turnover and the result of measures taken to improve the small and medium-sized business segment in the Kemerovo Region are analyzed.
Strategic priorities of domestic tourism development – balanced development of the Russian Federation regions
Authors: Larionova A. A. , Chernikova L. I. , Fedlyuk E. V.
Published: December 2019

The relevance of the research is determined by the need to assess the domestic tourism at the present stage to solve the strategic problem of balanced development of the Russian Federation. The article assesses the dynamics of the domestic tourism flow by such parameters as the number of people placed in collective accommodation facilities, the number of tours sold, the duration of trips, the dynamics of paid services in the context of the regions of the Russian Federation. The analysis allows us to conclude about the nonuniform distribution of the domestic tourism flow, a high degree of its concentration. The authors emphasize that in order to consolidate measures of targeted support of individual regions, the issues of assessing interregional tourism flows in individual regions are of great importance.  The article is prepared according to the results of studies carried out at the expense of budgetary funds on the government assignment of the Financial University under the Government of the Russian Federation of 2019.
Development strategy of agriculture On example SPK« Рlemzavod Мaysky»
Authors: Poletaev D. I. , Prozorova, M. L.
Published: December 2019

The article describes strategy of development of agriculture. Strategic development is aimed at considering alternative development strategies. In the concept of formation of the strategy of development of agriculture the set of reference points aimed at statement of the purposes and tasks which decision will make possible to form stable at progressing its development is offered. A system of indicators for forecasting the development strategy of agricultural enterprises is developed.
Evaluation of the reliability of space technology products in terms of statistically heterogeneous information
Authors: Makarov M. I. , Rudakov V. B. , Makarov V. M.
Published: December 2019

Analysis of known mathematical models of combining statistically heterogeneous information to improve the accuracy of the reliability assessment of space technology products at the stage of ground testing is carried out. The limited possibility of practical use of these models is shown in connection with the ambiguous choice of the level of significance of the hypothesis of statistical data belonging to one general population. The «weight» model of combining information not related to the choice of a specific level of significance in the evaluation of reliability is considered. All the components of this model is justified using the method of least squares and N.V. Smirnov’s criteria using the maximum ratio for combining statistical distribution functions.
Methods for increasing the noise immunity of the synchronization channel a telemetric signal
Authors: Salnikov O. N. , Poluban A. D.
Published: December 2019

Frame synchronization methods plays an important role in the process of restoring telemetry data transmitted through communication channels with noises of various origins, and significantly affects the efficiency of the recovery procedure. Frame synchronization is important in the event that the nature of interference in the communication channel and the methods of processing the transmitted information allow the transmission of reliable and false messages to the data stream of telemetry, as well as stop and resume transmission at random times
Influence of constructive features of symmetric data transmission chains on the process of optimizing the physical level of infocommunication systems
Authors: Semenov А. B. , Zubilevich A. L. , Abbasova T. S.
Published: December 2019

The influence of the twisting steps of twisted pairs of horizontal LAN cables of category 6 on the primary and key secondary parameters of the electrical transmission medium of infocommunication systems is investigated. The primary parameters are investigated, which make it possible to determine the secondary parameters of a symmetrical conductive path: wave impedance and attenuation coefficient. It is shown that, with respect to a twisted pair with the smallest twist pitch, it is expedient to apply the high-frequency model to calculate the electric transmission path.
Improving the management system for the distribution of materials in a blast furnace using a conical charging device
Authors: Kopytov A. A. , Ryabchikov M. Yu. , Ryabchikova E. S.
Published: December 2019

В статье рассмотрена задача организации автоматической подачи материалов в доменную печь при необходимости обеспечить требуемую схему распределения материалов по радиусу, а также устранить перепады уровней между секторами. Рассмотрены особенности радарных уровнемеров. Показано, что существующие схемы установки датчиков уровня не ориентированы на контроль распределения материалов по радиусу печи. Предложен алгоритм управления, обеспечивающий реализацию программы распределения материалов по радиусу и компенсацию неравномерности уровней по секторам в едином цикле выгрузки материалов.
Comprehensive calculation and experimental method for assessing the reliability of technical systems of aerial vehicle
Authors: Isaev V. G. , Seregin N. G. , Sorokin S. V.
Published: December 2019

The article considers a complex calculation and experimental method for evaluating the reliability of aircraft technical systems at the design and development stages of prototypes. The forecasting of reliability of technical systems by analytical methods is given. A brief presentation about mathematical modeling of products is given. Operational and bench accelerated tests of technical systems are considered. The necessity of complex analysis of analytical forecasting methods, operational and bench accelerated tests is shown to assess the reliability of technical systems of aircraft during the design and development stages of prototypes.
The main directions of improvement of methods of statistical control of reliability of automatic spacecraft and their systems at ground testing
Authors: Makarov V. M.
Published: December 2019

The analysis of the main directions of development of automatic spacecraft (AKA), the organization and features of the ground testing of their systems, as well as the main methods of statistical control of their reliability is carried out. The General characteristic of AKA as the object of research is given, the main directions of improvement of the existing methods of statistical control of reliability of AKA and the systems entering into it at their ground working off are defined.
Structuring and visualization of indicators in multidimensional data cubes
Authors: Akimkina E. E.
Published: December 2019

The problems of structuring of indicators in multidimensional data cubes with their subsequent processing with the help of end-user tools providing multidimensional visualization and data management are analyzed; the possibilities of multidimensional data processing technologies for managing and supporting decision making at a design and technological enterprise are shown; practical recommendations on the use of domestic computer environments for the structuring and visualization of multidimensional data cubes are given.
Synthesis of symmetrical cables for infocommunication systems with improved noise immunity characteristics
Authors: Semenov А. B. , Abbasova T. S.
Published: December 2019

A synthesis of construction of cables of category 6a for infocommunication systems with improved characteristics of noise immunity is carried out. The parameters of transient pickups and total transient pickups for the proposed cable design are calculated, and the cable diameter of the initial and proposed designs is estimated. The estimation of improvement of mass-dimension parameters of a cable of a proposed design is carried out. It is shown that due to chamber (group) unearthed screening, it is possible to significantly reduce the influence characteristics and the mass-dimensional parameters of the cable.
Features of architecture of security assessment complexes
Authors: Kravchenko N. A.
Published: December 2019

The article analyzes the tasks of combating threats in the information field and the place of security assessment tools in their context. The features of the architecture of the assessment complexes of various information security tools are analyzed. For an example of assessing the Security information and event management (SIEM), Ishikawa diagram was constructed. On the basis of its analysis, conclusions were drawn about the factors influencing the implementation of the test plan.
Decision-making support technology in regional security network-centric control system
Authors: Masloboev A. V.
Published: December 2019

The paper considers decision support problems in management of regional socio-economic system development. A decision-making support technology for regional security network-centric control, differing by the structure and implementation technique of coordination and prediction formal procedures of regional security indicators within the decision-making unit of the regional management system, has been developed. The technology is oriented to situational center information-analytical support in the region.