bluuebunny/crossref_metadata_2025 huggingface dataset:
The Efficacy of a Logotherapy Educational Program Based on Rumi’s Thoughts on the Mental Well-being of Chronic Mental Patients’ Families
Authors: Moshashai Seyyed Kianuddin , Yarahmadi Yahya , Sharifi Hasan Pasha
Published: April 2023

Objectives: The aim of this study was to investigate the efficacy of a logotherapy educational program based on Rumi’s thoughts on the mental well-being of chronic mental patients’ families. Methods: This study employed a semi-experimental controlled pretest-posttest design. The statistical population comprised families of all chronic mental patients (aged 18 to 60) who lived in Kermanshah’s rehabilitation and care facilities in 2020. One facility was randomly selected as the research sample, and 32 eligible individuals were randomized to experimental (n = 16) and control (n = 16) groups. Upon assignment, both groups completed the Warwick-Edinburgh Mental Well-being scale (2007) as the pretest. Subsequently, the experimental group participated in ten 90-minute sessions of logotherapy based on Rumi’s thoughts. At the conclusion of the intervention, the posttest was administered to both groups. The data were analyzed using an analysis of covariance. Results: The findings revealed a statistically significant difference between the two groups, indicating that the logotherapy educational program based on Rumi’s concepts increased the experimental group’s mental well-being compared to the control group (P < 0.001). In other words, families who participated in the Rumi-inspired logotherapy program experienced improved mental well-being. Conclusions: Families of chronic mental patients in our culture have a greater acceptance and comprehension of them. Furthermore, these cultural metaphors and allegories have increased the ability of chronic mental patients’ families to make sense of their sufferings, demonstrating its effectiveness as an intervention.
A Comparative Study on Outcomes of Retrograde Intrarenal Surgery (RIRS), Mini Percutaneous Nephrolithotomy (PCNL), and Extracorporeal Shock Wave Lithotripsy (ESWL) for Lower Pole Renal Calculi of < 1.5 cm
Authors: Ram Dhayal Ishwar , Gupta Rakesh , Srivastava Alok , Rai Priyanka
Published: April 2023

Background: Percutaneous nephrolithotomy (PCNL), established in the 1970s, has replaced open surgery for large stones. Extracorporeal shock wave lithotripsy (ESWL), once the preferred first-line treatment for small-to-medium-sized renal stones, has a questionable charm owing to patient reluctance for repeated treatments and hospitalizations since ESWL has a reduced stone-free rate (SFR). Flexible ureterorenoscopy, also referred to as RIRS, originally applied in the management of lower pole stones resistant to ESWL, is increasingly being used as a primary modality to manage lower pole stones, and it may potentially achieve higher SFR than ESWL and lower morbidity than PCNL for patients with low-volume stone diseases. Objectives: Observations were made to compare ESWL, mini PCNL, and RIRS in managing lower pole renal calculi of < 1.5 cm. Methods: This observational study encompassed all patients with lower pole renal stones with < 1.5 cm diameter and < 1000 HU density who underwent mini PCNL, RIRS, or ESWL from January 2020 to July 2021. There were 40, 60, and 60 patients in the RIRS, mini PCNL, and ESWL groups, respectively, for all of whom preoperative CT urogram was performed. The patients were informed of the procedures, and their informed consent was obtained. The stone-free rates of the three modalities were compared, and the outcomes were statistically analyzed. Results: The mean stone sizes in the present study were 12.99 × 3.56 mm in mini PCNL, 10.62 × 2.51 mm in RIRS, and 10.93 × 3.13 mm in ESWL. The mini PCNL group's SFR was significantly higher than those of other groups: 59 (98.3%) in mini PCNL, 34 (85%) in RIRS, and 46 (76.7%) in ESWL (P = 0.002). Out of the 60 patients in the mini PCNL group, only one (1.7%) required an ancillary procedure, while only six (10%) out of 40 patients in the RIRS group and 11 (18.33%) out of 60 patients in the ESWL group required the ancillary procedure (P = 0.031). Conclusions: For lower pole renal calculi < 1.5 cm, mini PCNL has the highest SFR, followed by RIRS and ESWL, in sequence. The ancillary procedure rate was 18.33% in the ESWL group, which was higher than those of mini PCNL (1.7%) and RIRS (10%).
EFFICACY OF INTRATHECAL MORPHINE AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Vu Van Kim Long , Nguyen Thi Tuyet Minh , Vo Nguyen Hong Phuc , Tran Van Dang , Le Vu Linh
Published: April 2023

Background: There have been many studies in using intrathecal morphine order to reduce pain after obstetrics and gynecological surgeries, abdominal surgeries and orthopedic surgeries. These studies have shown that intrathecal morphine is very effective for pain relief after surgery. However, intrathecal morphine also has side effects especially in obstetric and gynecological surgeries such as pruritus, postoperative nausea and vomiting, and delayed respiratory depression. Although postoperative analgesia with intrathecal morphine has been widely used in obstetrics and gynecological surgeries, orthopedic surgeries, there have been very few studies on postoperative pain relief with intrathecal morphine for colorectal surgery. Laparoscopic colorectal surgery requires multimodal analgesia, so using intrathecal morphine to reduce postoperative pain in this surgery is essential in clinical practice. Therefore, studying the effectiveness of intrathecal morphine in this surgery is necessary, so we conducted this study. Objectives: To assess the effectiveness of analgesic and side effects of intrathecal morphine after laparoscopic colorectal surgery. Materials and Methods: This was a descriptive, cross-sectional study, including 63 patients undergoing laparoscopic colorectal cancer surgery with intrathecal morphine before general anesthesia. The degree of analgesia was assessed based on VAS. The postoperative side effects observed were postoperative nausea and vomiting, respiratory depression, and pruritus. Results: The analgesic effect at rest and on slight movement was 95.2%, and 88.9% respectively with VAS ≤ 3. The side effects were postoperative nausea and vomiting (6.3%), and pruritus (1.6%), both postoperative nausea and vomiting and pruritus (3.2%). In conclusion, 300µg intrathecal morphine showed a safe and positive analgesic effect for laparoscopic colorectal cancer surgery.
VARIANTS OF THE CIRCLE OF WILLIS ON NON-CONTRAST MAGNETIC RESONANCE ANGIOGRAPHY
Authors: Lam Buu Nguyet , Nguyen Hoang Thuan , Nguyen Truong Tho , Nguyen Vinh Quang , Huynh Huu Phuc , Nguyen Phuong Thao
Published: April 2023

Background: The Circle of Willis (CoW) distributes oxygenated blood throughout the brain and represents the only major anastomosis of the brain. The study of variations in CoW is crucial for avoiding confusion of the anomalies with aneurysms, evaluating collateral pathways in the intracerebral circulation, and enhancing pre-operative planning in patients undergoing surgery at the skull base. Objectives: Evaluate and describe the prevalence of variations of the CoW by using three-dimensional time-of-flight MR angiography (3D-TOF-MRA). Materials and methods: We conducted a cross-sectional description in 102 patients after meeting the requirements of inclusion criteria. All participants were scanned in a GE Optima 360 1.5T MRI scanner. The variants of the CoW were studied. The correlation between variations in relation to gender and age were evaluated. Results: Among 102 samples, the mean age was 46, and female dominance was seen among participants (60.80%). The proportion of CoW with normal shape (7 edges) as in classical anatomy is 10.78%. The highest prevalence of variations was seen in PCOM-R with 62.75% (64/102) and PCOM-L with 58.82% (60/102). We recorded 32 types of CoW variation, including 7 single variants accounting for 26.37% (24/91) and 25 combined variants with 73.63% (67/91), some of which had not been reported in previous studies. Conclusion: The complete configuration of the CoW was seen in 10.78% of population. 32 types of CoW variation, including 7 single variants (26.37%) and 25 combined variants (73.63%) were recorded.
Framework für eine erfolgreiche ERP-Transformation
Authors:   mgm consulting partners gmbh , Brugger Thomas , Czeslik Markus , Echter Peter , Hager Ariane
Published: April 2023

Ausgebremste oder gescheiterte ERP-Projekte sind leider kein Einzelfall. Die Ursachen dafür liegen zumeist in der Komplexität des Vorhabens begründet, denn die Einführung von ERP-Systemen wie z. B. SAP S/4HANA ist mehr als nur eine technische Umstellung. Es stellt eine große Veränderung in den Prozessen und der Arbeitsweise eines Unternehmens dar und bietet strategische Chancen, um im digitalen Zeitalter wettbewerbsfähig zu bleiben. Deshalb betrachten wir ERP-Transformationen auch als Möglichkeit, die Unternehmenskultur weiterzuentwickeln und Agilität und Selbstorganisation im Alltag zu verankern.
Legal Review of Child Grooming as A Crime of Sexual Violence in Indonesia
Authors: Pujayanti Luh Putu Vera Astri , Sopian  , Sulaiman Herlina , Sahrul  , Misno
Published: April 2023

The phenomenon of sexual violence is an issue that is increasingly being discussed in Indonesia. Sexual violence can happen to anyone, both women and men, but most victims are women. Children are a group that is very vulnerable to sexual violence because children are always positioned as weak or powerless and have a high dependence on the adults around them. This is what makes children helpless when threatened not to tell what happened. In almost every case uncovered, the perpetrators are people close to the victims. One of the sexual violence that occurs in children is the rise of the child grooming phenomenon in Indonesia, a new form of crime. Child grooming in Indonesia, or sexual exploitation crimes against children using social media, is increasing because the demand for the global sex market is getting bigger. This research uses normative research, which is analytical descriptive through a Statute Approach, techniques through data source studies/data collection carried out by literature (secondary data). The results of this study indicate that child grooming is a practice carried out by adults to attract attention and manipulate minors for sexual purposes or other crimes. In Indonesia, grooming children has been made a crime of violence against children based on Law Number 35 of 2014 concerning Child Protection.
Synthesis of 5-phenoxyprimaquine derivatives and their tetraoxane conjugates as anti-malarial agents
Authors:   , Jansongsaeng Somruedee
Published: April 2023

Currently, the development of the new anti-malarial drug for the treatment of the increasing drug-resistant strains of malaria was necessary. Therefore, this research was performed by synthesis and evaluation of their antimalarial activity for the development of primaquine which currently was used for anti-malarial drug. The substituents group on 5-phenoxyprimaquine derivatives which had the highest therapeutic index and less toxicity than primaquine were emphasized. The effect of substituted group at para position was studied. Three new derivatives with CN (7e), CF3 (7g), CONH2 (7h) substituents, and five known derivatives with OMe (7b), Br (7c), Cl (7d), F (7f) substituents and the unsubstituted derivative (7a) of primaquine were synthesized. Their structures were characterized by 1H, 13C, 19F NMR and HRMS techniques. In addition, all synthesized compounds were evaluated for their anti-malarial activity using Malaria SYBR Green I-base fluorescence (MSF) assay against P. falciparum 3D7 in the blood-stage. 7a exhibited the greatest inhibitory effects with the IC50 value of 3.65 ± 0.39 µM comparing with primaquine (IC50 = 11.33 ± 0.79 µM) and another derivative with IC50 values ranging from 4.62 to 13.5 µM. Subsequently, 7a conjugated with tetraoxane 14 using a linker of four carbon to afford new 5-phenoxy primaquine-tetraoxane conjugated (15). Pleasingly, 15 exhibited inhibitory effects with IC50 values of 0.38 ± 0.11 µM, which was 30-fold more potent than that of the primaquine. Moreover, new compound 7e and 15 with high antimalarial activity had selectivity index (SI) values of more than 25 and 45.61, respectively.
Effect of fly ash in Southeast Asia on the properties of concrete
Authors:   , Win Thwe
Published: April 2023

A wide use of fly ash (FA) as a supplementary cementitious material (SCM) can result in an enhancement in its durability performance in our civil engineering applications. Although FA is either agricultural or industrial by‑product and is abundant for use in cement and concrete works for many decades now, the utilization of FA still has a practical challenge. The challenge is due to variability and their heterogeneity. In Southeast Asia, fly ash is used in concrete production replacing cement as a pozzolanic material. However, there are few standard guidelines for using fly ash across the region. This study evaluates the durability of cementitious materials after the including of five types of fly ash in different mix proportions from three countries, Myanmar, Thailand, and Indonesia. For the mathematical model, each type is used to replace ordinary Portland cement in 15 % with a water-to-binder ratio of 0.54. Moreover, this work is to perform both experimental and numerical studies to have a better insight for controlling the different FA, reflecting its durability. FA from five different sources were assessed to investigate the impacts on its chemical composition and physical properties. The blended FA-cement systems were also prepared and evaluated on its flow, compressive strength of mortar, hardened porosity, ability to resist chloride penetration, apparent chloride diffusivity coefficients (Da), and carbonation resistance after 7, 28, and 91 days, and degree of reaction. Because the chemical composition of each country’s fly ash is slightly different, their chemical reaction with cement is marginally different. Thus, the durability performances of the mortar are better for finer fly ash types at an early age. The service life model using Life365 was performed to predict the service life of blended FA-cement system. The experimental results were statistically analyzed using analysis of variance (ANOVA) and sensitivity analysis with linear regression. The analyses indicate that chemo-physical mechanisms of multi-scale structures are the main factors, and both degree of reaction of blended FA-cement systems and its hardened porosity are among the most positive factors influencing its durability.
Identifying, analyzing, and managing challenges in administering construction contracts of large public projects in Bhutan
Authors:   , Gyem Tandin
Published: April 2023

Construction projects encompass three major phases: pre-construction, construction, and post-construction. Although various problems are inevitable in every phase, most of them occur during construction and can be mitigated by adopting a good construction contract for project management. A construction contract is a formal agreement between the project owner and the construction contractor. An important contract document is the conditions of contract (COC), which encompass the rules and regulations for administering the contract. In Bhutan, all public construction projects are mandated to follow the Bhutan Standard Bidding Documents for Procurement of Works 2019 and the form of General Conditions of Contract (GCC). Both documents are considered the nation’s standard form of construction contract. Although these documents are updated regularly, implementing them in construction projects is often faced with various challenges. This research identifies major challenges associated with contract administration in the public projects in Bhutan. To identify these challenges, we conducted an in-depth interview with a group of local procurement professionals, government engineers, and contractors. Among the 26 factors contributing to the challenges identified from the interview, it was found that 15 factors were associated with the challenges in contract administration of the large public projects in Bhutan. These factors were further analyzed to determine the priority level using a likelihood of occurrence and time/cost impact matrix. We then proposed the recommendations to address the challenges caused by these factors by considering the standard form of construction contract by the International Federation of Consulting Engineers (FIDIC) and the experts' opinions. The identified challenges and the proposed recommendations can help the relevant authorities make rational decisions and enhance the efficiency of the existing standard form of construction contract in Bhutan.
Aloe vera and health outcomes: an umbrella review of systematic reviews and meta-analyses
Authors:   , Sadoyu Saranrat
Published: April 2023

This umbrella review aims to summarize and assess the effects of Aloe vera on health outcomes. Methods: Only systematic reviews and meta-analyses of clinical trials that investigated the effects of Aloe vera on health outcomes were eligible. PubMed, Scopus, Embase, Cochrane database of systematic reviews, CINAHL, and AMED were searched from inception to October 2019. Two independent reviewers extracted data, assessed the methodological quality, and rated the credibility of evidence according to established criteria into convincing, highly suggestive, suggestive, weak, and not significant. Results: Ten articles reporting 71 unique outcomes of Aloe vera were included. Of these, 47 (67%) were nominally statistically significant based on the random-effects model (p ≤ 0.05). Only 3 outcomes were supported by highly suggestive evidence including the benefits of Aloe vera in the prevention of second-degree infusion phlebitis (RR: 0.18, 95% CI: 0.10-0.32) and chemotherapy-induced phlebitis based on the second-degree of severity and overall incidence (OR: 0.10, 95% CI: 0.07-0.14, and OR: 0.13, 95% CI: 0.08-0.20, respectively). Conclusions: The current evidence suggests the benefits of Aloe vera in the prevention of phlebitis induced by chemotherapy and intravenous infusion, particularly in the severe stage. Aloe vera also showed favorable effects in other indications, but the majority of the evidence had limitations including small sample size and poor methodological quality.
The effects of limited infusion rate of fluid in the early resuscitation of sepsis on syndecan-1 shedding: a randomized controlled trial (life3s trial)
Authors:   , Saoraya Jutamas
Published: April 2023

Background: Aggressive fluid administration is recommended in the resuscitation of septic patients. However, the delivery of a rapid fluid bolus might cause harm by inducing degradation of the endothelial glycocalyx. This research aimed to examine the effects of the limited infusion rate of fluid on glycocalyx shedding as measured by syndecan-1 in patients with sepsis-induced hypoperfusion. Methods: A prospective, randomized, controlled, open-label trial was conducted between November 2018 and February 2020 in an urban academic emergency department. Patients with sepsis-induced hypoperfusion, defined as hypotension or hyperlactatemia, were randomized to receive either the standard rate (30 ml/kg/hr) or limited rate (10 ml/kg/hr) of fluid for the first 30 ml/kg fluid resuscitation. The primary outcome was the change in plasma syndecan-1 levels over six hours. Secondary outcomes included adverse events, organ failure and 90-day mortality. Results:  We included 96 patients in the intention-to-treat analysis, with 48 assigned to the standard-rate strategy and 48 to the limited-rate strategy. The median fluid volume in six hours in the limited-rate group was 39 ml/kg (interquartile range [IQR] 35 – 52 ml/kg) vs. 53 ml/kg (IQR 46-64 ml/kg) in the standard-rate group (p < 0.001). Patients in the limited-rate group were less likely to received vasopressors (17% vs 42%; p = 0.007) and mechanical ventilation (20% vs 41%; p = 0.049) during the first six hours. There were no significantly different changes in syndecan-1 levels at six hours between the two groups (geometric mean ratio [GMR] in the limited-rate group, 0.82; 95% confidence interval [CI], 0.66 – 1.02; p = 0.07). There were no significant differences in adverse events or organ failure outcomes or 90-day mortality between the two groups. Conclusions: In sepsis resuscitation, the administration of resuscitative fluid with the limited-rate strategy did not significantly mitigate the glycocalyx damages compared to the standard-rate approach.
Vaginal atrophy treatment using microablative fractional carbon dioxide laser: a randomized patient and evaluator-blinded sham-controlled trial
Authors:   , Ruanphoo Purim
Published: April 2023

Introduction: In recent years, microablative fractional carbon dioxide (CO2) laser becomes popular in treatment of vaginal symptoms including vaginal atrophy. This study aimed to evaluate efficacy of vaginal CO2 laser in treatment of vaginal atrophy, compared to the sham procedure. Methods: Between June 2016 and May 2017, postmenopausal women with moderate to severe intensity of any symptoms of vaginal atrophy were invited to the study. A total of 88 women were randomized for treatment with vaginal CO2 laser or sham procedure every 4 weeks for 3 sessions. The participants were blinded to the intervention they received. The operator was also blinded from outcomes of those participants. Vaginal health index (VHI) score, vaginal atrophy symptom (VAS) score and vaginal dryness item of the ICIQ-VS questionnaire were compared between groups at 12-week follow-up based on intention to treat analysis. Results: Eighty-eight women were included and 9 women were lost to follow-up. All outcomes of women who received laser treatment significantly improved over 12 weeks, including VHI (p<0.001), VAS (p<0.001), ICIQ-VS (vaginal dryness item) score (p=0.02). When compared both groups at 12 weeks after procedure with intention-to-treat analysis, VHI and VAS score of laser group significantly improved when compared to the sham group (p<0.001 and <0.001 with mean difference of 1.37 (95% CI: 0.12 to 2.63) and -1.52 (95% CI: -2.21 to -0.82) respectively). Conclusions: This study demonstrated that vaginal microablative fractional CO2 laser was effective in treatment of vaginal atrophy. It could be a promising alternative treatment of postmenopausal women with vaginal atrophy.
การพัฒนารูปแบบและกลไกขับเคลื่อนอุทยานเศรษฐกิจฐานความรู้ของสถาบันอุดมศึกษาในประเทศไทย
Authors:   , บัวใจบุญ กิตติโชติ
Published: April 2023

การวิจัยนี้มีวัตถุประสงค์เพื่อวิเคราะห์การจัดการอุทยานวิทยาศาสตร์และเทคโนโลยีในต่างประเทศที่สนับสนุนบทบาทหน้าที่ของสถาบันอุดมศึกษา วิเคราะห์ความต้องการด้านเทคโนโลยีและนวัตกรรมสำหรับสถาบันอุดมศึกษาในประเทศไทย พัฒนารูปแบบและนำเสนอกลไกการขับเคลื่อนอุทยานเศรษฐกิจฐานความรู้สำหรับสถาบันอุดมศึกษาในประเทศไทย โดยการวิเคราะห์เอกสารเกี่ยวกับอุทยานวิทยาศาสตร์และเทคโนโลยีจากสถาบันอุดมศึกษาในต่างประเทศ ได้แก่ สถาบันเทคโนโลยีแมสซาชูเซตส์ มหาวิทยาลัยเคมบริดจ์ มหาวิทยาลัยเกียวโต และมหาวิทยาลัยแห่งชาติสิงคโปร์ และเก็บข้อมูลจากการวิเคราะห์เอกสาร สัมภาษณ์ สอบถามผู้บริหารระดับสูงและผู้บริหารหน่วยงานระดับคณะ วิทยาลัย สถาบัน ของสถาบันอุดมศึกษาในประเทศไทยของรัฐและเอกชน จำนวน 13 แห่ง ผู้บริหารหน่วยงานภาครัฐและภาคเอกชน 12 แห่ง และการประเมินร่างรูปแบบและกลไกฯ จากผู้ทรงคุณวุฒิ การวิเคราะห์ข้อมูล ได้แก่ การวิเคราะห์เนื้อหา และความถี่ ผลการวิจัยพบว่า 1. การจัดการอุทยานวิทยาศาสตร์และเทคโนโลยีในต่างประเทศสนับสนุนบทบาทหน้าที่ของสถาบันอุดมศึกษา สอดคล้องกับพันธกิจของสถาบันอุดมศึกษาด้านการเรียนการสอน การวิจัย และการบริการวิชาการ และบทบาทสถาบันอุดมศึกษาเพื่อการวิจัยในการพัฒนาสถาบัน เศรษฐกิจ สังคม และประเทศ 2. การจัดการด้านเทคโนโลยีสารสนเทศและนวัตกรรมที่นำไปสู่อุทยานเศรษฐกิจฐานความรู้ของสถาบันอุดมศึกษาในประเทศไทย พบว่า กลุ่มมหาวิทยาลัยวิจัยแห่งชาติ มีการจัดการด้านเทคโนโลยีสารสนเทศและนวัตกรรมที่นำไปสู่อุทยานเศรษฐกิจฐานความรู้สูงที่สุด รองลงมาได้แก่ กลุ่มมหาวิทยาลัยในกำกับของรัฐ และกลุ่มมหาวิทยาลัยเอกชน ตามลำดับ ในด้านการจัดการหน่วยงาน การเรียนการสอน การวิจัย บริการวิชาการ และทำนุบำรุงศิลปะและวัฒนธรรม
3. รูปแบบอุทยานเศรษฐกิจฐานความรู้สำหรับสถาบันอุดมศึกษาในประเทศไทย มีรูปแบบและระดับการพัฒนา ได้แก่ 1) รูปแบบอุทยานเศรษฐกิจฐานความรู้เพื่อการพัฒนาสถาบัน 2) รูปแบบอุทยานเศรษฐกิจฐานความรู้เพื่อการพัฒนาท้องถิ่น/สังคม (เฉพาะทาง) 3) รูปแบบอุทยานเศรษฐกิจฐานความรู้เพื่อพัฒนาเศรษฐกิจ/เชิงประกอบการ (วิชาการ) และ 4) รูปแบบอุทยานเศรษฐกิจฐานความรู้เทคโนโลยีขั้นสูง/นวัตกรรม 4. กลไกการขับเคลื่อนอุทยานเศรษฐกิจฐานความรู้สำหรับสถาบันอุดมศึกษาในประเทศไทยประกอบด้วย 1) กลไกขับเคลื่อนด้านการบริหารจัดการ 2) กลไกขับเคลื่อนด้านโครงสร้างพื้นฐาน 3) กลไกขับเคลื่อนด้านความร่วมมือ และ 4) กลไกขับเคลื่อนด้านผลผลิต อุทยานวิทยาศาสตร์และเทคโนโลยีเป็นการจัดการวิจัยในสาขาวิทยาศาสตร์และเทคโนโลยีและสาขาสังคมศาสตร์และมนุษยศาสตร์ภายใต้สถาบันอุดมศึกษา โดยที่มีองค์ความรู้เป็นฐานที่มีโดยลักษณะการจัดการวิจัยองค์ความรู้เพื่อการสร้างมูลค่าและคุณค่า การปรับเปลี่ยนไปสู่อุทยานเศรษฐกิจฐานความรู้จึงมีความครอบคลุมลักษณะความเป็นนิคมวิจัยที่มีองค์ความรู้เป็นฐาน สอดคล้ององค์ความรู้ที่มีความหลากหลายสาขาและสภาพสาขาวิชางานวิจัย และคงบทบาทสนับสนุนพันธกิจของสถาบันอุดมศึกษา
Techno-economic analysis of diethyl ether production via catalytic dehydration of ethanol
Authors:   , Chaiapha Boonraksa
Published: April 2023

The major source of energy comes from non-renewable fuels, which have a non-sustainability and negative impact on the environment. Thus, there is change to renewable fuels as bioethanol. Diethyl ether (DEE) is a part of bioethanol. However, the increase of electric vehicles (EV) may decrease ethanol demand for biofuel in the future. Thus, it will be interesting in adding value to ethanol via the catalytic dehydration to produce DEE by conduct techno-economic analysis. Further, there is comparison on different concentrations of ethanol (93% and 95% ethanol) that affect DEE production. For simulation part, the DEE capacity of 3,600 tons/year is the most profitable due to the highest %IRR and offers a shorter POP. The highest energy consumption of electricity and thermal duty is at the DEE capacity of 3,600 tons/year as well as the CO2 emission due to the large utility is required and larger CO2 content is released. For experiment part, the water content in the ethanol solution has effect on the Ru-HBZ catalyst. For ethylene yield, the water content has slight effect on the catalyst at 400°C. In contrast, for DEE yield, the water content has a greater effect on the catalyst at 250°C due to the water molecule resulted in an increase the Brønsted acidity and blocking of Lewis acid sites, to the lower activity of the catalyst. By-product is acetaldehyde when the water content increases, the acetaldehyde yield increases.
Development of novel comprehensive multidimensional gas chromatography for improving separation and analysis of propylene oxide sample
Authors:   , Janta Pannipa
Published: April 2023

New experimental and data analysis approaches in multidimensional gas chromatography (MDGC) comprising  1) comprehensive two dimensional GC (GC×GC) and 2) comprehensive multiple heart-cut were developed with an example application illustrated for analysis of propylene oxide sample. GC×GC system employed column set of long first dimensional (1D) nonpolar (60 m) and short second dimensional (2D) polar (5 m) columns with a flow modulator and a Deans switch (DS) as a splitter; whilst, the comprehensive heart-cut system applied solely a DS located between long 1D nonpolar (60 m) and 2D polar (60 m) columns without use of cryogenic trapping devices. Under the same oven temperature program, the effects of different experimental conditions on the separation performances in GC×GC (injection time of the flow modulator and 2D column flow) and in comprehensive heart-cut ( heart-cut window and number of injections) were investigated. The analysis performance for each condition was evaluated according to peak capacity and number of separated compounds. The continuum between the two techniques was then established based on the analysis time vs analysis performance relationship. The separation performances were improved with longer analysis time so that the suitable condition can be selected within this compromise. The injection time of 0.60 s and 2D column flow of 14.0 mL/min were proposed as the best condition in GC×GC. For  comprehensive heart-cut, the heart-cut window of 0.20 min with analysis time of 25 h was the selected condition. Under these conditions, volatile compounds in propylene oxide sample were identified according to matches between the experimental mass spectrometry (MS) spectra and first dimensional retention indices (1I) with that from NIST2014 database and the literatures. An hour analysis with GC×GC resulted in total peak capacity of 798, number of separated peaks of 61, number of identified compounds of 27 and average MS match score of 887±35. The corresponding numbers were improved to 9198, 107, 38 and 898±24, respectively, with the 25 h comprehensive heart-cut analysis.
Regenerated amorphous cellulose from pineapple leaf fibers via sulfuric acid treatment
Authors:   , Asmarani Gisma
Published: April 2023

Pineapple leaf fiber (PALF) is an agricultural residue available abundantly in Thailand as a renewable resource with high cellulose content. In this research, a simple process using sulfuric acid (H2SO4) treatment has been developed to produce three types of cellulosic products from PALF, which are regenerated amorphous (RAC), microcrystalline (MCC), and nanocrystalline (NCC) cellulose. H2SO4 acid treatment has been done in 25% and 50% (v/v) H2SO4 under three different temperatures (-20, 30, and 50 ºC). In 25% (v/v) H2SO4, various MCC lengths (about 29.57 ± 9.99 to 106.40 ± 61.10 μm) were produced from different temperatures. Different temperatures in this condition gave the ability to control the MCC size without changing the chemical structure, confirmed by OM images and FT-IR spectra. Compared to the commercial MCC, Avicel PH101, MCC PALF obtained in this work offers definite advantages over Avicel PH101 regarding aspect ratio and uniformity. MCC PALF can be a potential alternative to produce a commercial MCC. In 50% (v/v) H2SO4, three kinds of cellulosic products were obtained and could be differentiated using OM, cross-polarizer, FT-IR, and XRD characterizations. RAC was obtained at -20 ºC, confirmed from the gel-like shape morphology, no birefringence shown, the crystalline band's disappearance at 1425 cm-1 and increment of the amorphous band at 897 cm-1 on FT-IR spectrum, and XRD patterns of amorphous cellulose with small peaks corresponding to cellulose II. MCC was obtained at 30 ºC, showing a short fiber morphology in OM image with length and width at 37.63 ± 14.19 and 3.85 ± 0.66 μm, respectively. NCC was obtained at 50 ºC, showing flow birefringence phenomena, confirmed by cross-polarizer. Producing RAC and NCC required adequate acid concentration and temperature treatment. By adjusting the temperature in an appropriate concentration, different products could be obtained.
ON THE ROLE OF THE RESULTS OF OPERATIONAL SEARCH ACTIVITIES IN CONTEMPORARY CRIMINAL PROCEEDINGS
Authors:   Ural Law Institute of the Ministry of Internal Affairs of Russia, Nazarov Mikhail V.
Published: April 2023

The article is devoted to the analysis of the place and role of operational-­investigative activities results (hereinafter — ORD) in modern criminal procedural law. The views established in science regarding the use of materials obtained in the course of conducting operational-­search activities (hereinafter referred to as ORM), as well as existing law enforcement realities, correlate with the views established in science regarding the use in criminal procedural evidence obtained during the conduct of operational-­search activities (hereinafter referred to as ORM). The article reveals the inconsistencies between the theoretical provisions and the requirements put forward by objective reality to expand the practice of using the capabilities of the operational units of the inquiry bodies for the purposes of criminal proceedings. The author aims to establish the reasons for the skeptical attitude of process scientists to the ORD results and substantiates the provisions on the leading role of the court, the prosecutor’s office as independent guarantors of human rights and a citizen in the implementation of individual ORM. Methodologically, research relied on the dialectical method of scientific knowledge, logical, comparative legal methods, as well as observation and other particular methods of studying legal phenomena. The research used doctrinal sources, as well as domestic legislation as the sources of study material. Conceptual proposals were put forward to improve the theory of criminal justice, with the aim of its rational updating, as well as possible ways to improve the Criminal Procedure Code of Russia.
THE IMAGE OF RUSSIA AS A CONSEQUENCE OF THE POLITICAL CONJUNCTURE, OR THE METAMORPHOSIS OF ABBÉ DE PRADT
Authors:   RANEPA, Tanshina Natalia P. ,   Moscow Pedagogical State University
Published: April 2023

The focus of the article, written within the framework of the imagological approach, is the reconstruction of the image of Russia in France during the years of the Restoration. The article is based on the analysis of the views of the famous French diplomat and politician Abbé D. de Pradt (1759–1837). The relationship between the image of Russia in France and the current political situation is revealed by the example of the journalistic works of Abbé de Pradt. The article sees Russophobia as a mechanism for solving French problems. It is also concluded that the image of Russia created in the West was, on the one hand, very stable and based on ingrained stereotypes of perception. On the other hand, this image depended on the political situation. The image of Russia created by Abbé de Pradt turned out to be very elastic, mobile, dependent on the political conjuncture. Abbé de Pradt never had any sympathy for Russia and created openly anti — Russian pamphlets. However, at the time when France was looking for an ally and saw Russia as such, rational Pradt diametrically changed his own position. At the same time, the optics of superiority, characteristic of post-­Napoleonic France, and the view of Russia as a power was never strong as it looked, remained an invariable feature of his works.
ACHIEVEMENTS AND CHALLENGES IN THE KALININGRAD HEALTHCARE SYSTEM DURING “REAL SOCIALISM”
Authors:   Immanuel Kant Baltic Federal University, Mankevich Dmitrii V.
Published: April 2023

The article identifies and examines a number of trends in the development of healthcare system in the Kaliningrad region in the second half of the 1960s and the first half of the 1980s in comparison with the national tendencies. The processes of this time, unlike the years of early development of Kaliningrad healthcare, are poorly studied. The main sources are the documents of the Health Department of the Kaliningrad region, Oblispolkom (Regional Executive Committee) and the Bureau of Medical Statistics from the respective funds of the State Archive of the Kaliningrad Oblast. Further development of the health infrastructure, the reduction of infant and maternal mortality, the success in developing the ambulance system, a significant increase in the number of doctors and paramedics, and the expansion of access to basic healthcare for citizens are the features of the period under review. However, not all staff problems had been solved. The weak point of the regional healthcare was oncological and dental care, the need for which was constantly increasing. There were difficulties with implementing construction plans for new objects of public health services, some of which had turned into real long-term projects. The lack of financing made it impossible to solve a number of problems related to the obsolescence of equipment and medical technology. Despite successes in the control of infectious diseases, there was a high incidence of dysentery and other intestinal infections in the region. The 1970s saw further development of the system of sanitary education, which reached a large proportion of the population of the region. However, the sources do not allow to assess the efficiency of this measure. Processes that were taking place in Kaliningrad regional healthcare system were typical for the country as a whole, showing slow increase in the manifestations of a systemic crisis. The peculiarities of the region, which mitigated this tendency, included high indicators of provision of medical workers in the region, a closer connection between rural and urban healthcare and a younger average age of the population.
FORT №5 IN THE HISTORICAL MEMORY OF KALININGRAD RESIDENTS
Authors:   Immanuel Kant Baltic Federal University, Fostova Suzanna A.
Published: April 2023

The Königsberg Fort № 5 “Friedrich Wilhelm III”, built in the second half of the 19th century was never used in military operations before the Second World War. But during the storm of Königsberg by the Soviet troops in April, 1945, it had been exposed to the attacks of all kinds of forces of the 3rd Belorussian front for four days and was surrendered by the German command. Later fifteen men were awarded the title of Hero of the Soviet Union for the fort storming. The article is based on the unpublished documents dating from 1970—1980s from the archives of the Kaliningrad Regional Museum of History and Art which are related to the events of the East Prussian invasion. The author studies the process of including the former German fortress in the historical memory of the Soviet Kaliningrad inhabitants. The article identifies the reasons for the museumisation of the fortress among other fortification structures and its formation as a place of memory. Two concept plans of turning the fort into a memorial are described and analyzed in detail: projects by sculptors from the Moscow organization Rosmonumentyskusstvo and by workers of the Regional Museum of History and Art. The conclusion is made about the principles of reconstruction and the limits of what is admissible in the process of adjusting the German monuments to the objectives of the memory policy aimed at filling the historic landscape of the city with the Soviet attributes. The conclusion substantiates the key role of the memorial opened at Fort № 5 as a mediator (media) between the past of the region and the inhabitants of the region to promote the historical narrative about the storming of Königsberg by the Red Army as the central event of the East Prussian operation of 1945.
Các yếu tố ảnh hưởng đến ý định mua hàng của sinh viên các trường đại học tại Thành phố Hồ Chí Minh: Nghiên cứu lĩnh vực sản phẩm nhãn hiệu riêng
Authors: Trần Thị Nhinh , Chung Huệ Nhã , Lê Thị Tường Vi , Nguyễn Hoài Nhật Thi
Published: April 2023

Mục tiêu nghiên cứu này là xác định các yếu tố ảnh hưởng đến ý định mua hàng của sinh viên đối với các sản phẩm nhãn hiệu riêng ở Thành phố Hồ Chí Minh. Nhằm khám phá mức độ liên kết và mối quan hệ của các yếu tố đó với ý định mua hàng và trên cơ sở phân tích đó phát triển các tác động quản lý đối với các nhà hoạch định chính sách và chủ cửa hàng để loại bỏ những cản trở trong sự phát triển của các thương hiệu tư nhân ở Thành phố Hồ Chí Minh, Việt Nam. Phương pháp nghiên cứu mà nhóm tác giả sử dụng là nghiên cứu hỗn hợp thông qua bảng câu hỏi khảo sát được thu thập với quy mô mẫu phân tích là 500 mẫu. Đối tượng thực hiện khảo sát là sinh viên đang học tập tại Thành phố Hồ Chí Minh (ĐH Ngoại Thương cơ sở 2, Tôn Đức Thắng, Sài Gòn, Công nghiệp Thực phẩm, Hoa Sen, Hồng Bàng). Kết quả nghiên cứu cho thấy có 5 yếu tố tác động đến ý định mua hàng của sinh viên là (1) Cảm nhận về chất lượng, (2) Cảm nhận về giá, (3) Hình ảnh cửa hàng, (4) Quảng cáo, (5) Bao bì, (6) Ý định mua hàng.
285 nm AlGaN-BASED DEEP-ULTRAVIOLET LED WITH HIGH INTERNAL QUANTUM EFFICIENCY: COMPUTATIONAL DESIGN
Authors: ALP İrem , ÖNER Bilgehan Barış , EROĞLU Esra
Published: April 2023

In this paper, the systematic computational design process of AlGaN-based multiple quantum-well (QW) deep-ultraviolet (DUV) light-emitting diode (LED) grown on sapphire (Al2O3) substrate was investigated. An optimization was held to increase internal quantum efficiency (IQE) handling the LED parameters such as doping percentage of the n- and the p-type layers of these devices. The structure parameters of the best design were determined through a customized genetic algorithm integrated into the nanostructure quantum electronic simulation (nextnano). As a determining factor, IQE was obtained to be 24% for the devised 285 nm LED. It has been demonstrated that this result can be increased up to a remarkably high value of 70% by a low threading dislocation density (TDD) and reduced Auger recombination. In addition, the operation input power and potential difference were successfully kept below 0.1 W/mm2 and 5.05 V, respectively.
INVERSE NEURO-FUZZY MODEL BASED CONTROLLER DESIGN FOR A PH NEUTRALIZATION PROCESS
Authors: AKCA Talha Burak , ULU Cenk , OBUT Salih
Published: April 2023

Since pH neutralization processes have extremely nonlinear characteristics, controlling it might be difficult. Therefore, a special controller design is needed to handle the high nonlinearities of the process. In this study, an inverse neuro-fuzzy model-based controller (NFMBC) design is presented for control of a pH neutralization process (NP). Input-output (IO) data set of the process is collected by applying a proper excitation signal. Then, forward and inverse neuro-fuzzy models of the process are constructed by using this data set after a training process. In terms of design simplicity, a two-input-one-output model structure is chosen for both neuro-fuzzy models. These forward and inverse neuro-fuzzy models are used in a nonlinear internal model control (NIMC) structure in order to provide robustness against disturbances and model mismatches. To examine the proposed controller's performance, simulation studies are carried out under setpoint variation and disturbance conditions. Additionally, the performance of the inverse NFMBC is compared to that of a fuzzy proportional integral derivative (FPID) controller with a 7x7 rule base. The results demonstrate that the designed controller provides more effective control performance for setpoint variations and also exhibits higher robustness against disturbances in the acid flow rate than the FPID controller.
A HYBRID MODIFIED SUBGRADIENT ALGORITHM THAT SELF-DETERMINES THE PROPER PARAMETER VALUES
Authors: SARAÇ Tuğba , TUTUMLU Büşra , AKYOL ÖZER Emine
Published: April 2023

A successful solution algorithm for non-convex optimization problems is the Modified Subgradient Algorithm (MSGA), which solves dual problems based on the sharp augmented lagrangian function. However, its performance highly depends on its parameter values, and determining the appropriate parameter values is difficult as they can be completely different for each problem. In this study, a new hybrid solution approach that a tabu search algorithm to find the appropriate MSGA parameter values and the MSGA algorithm run together is proposed. Although it seems like a contradiction to use an algorithm that also has its parameters to determine the most appropriate parameter values of an algorithm, this contradiction is eliminated by fixing the parameter values of the tabu search algorithm. The proposed algorithm does not need appropriate values of any algorithm parameter. It can find appropriate parameter values for each problem itself starting with the same fixed initial values. To show the success of the developed algorithm, especially on 0-1 quadratic problems, it is compared with the classical MSGA algorithm by using the quadratic knapsack test instances taken in the literature. According to the obtained solutions, the superiority of the hybrid algorithm has been demonstrated.
CHEMICAL AND MINERALOGICAL ANALYSES OF THE LATE NEOLITHIC CERAMICS FROM ŞAH VALLEY (SINGUBER), TURKEY
Authors: BAYAZİT Murat , KAYNAK Esra , COŞKUN Nilgün
Published: April 2023

Numerous settlements have been identified during the surveys in Şırnak province (Turkey) since the beginning of the 19th century. The potsherds found in the central of such settlements have been thought to be affected by Mesopotamian culture, and the ones from the hillside of the Şah Valley were considered as the most eastern examples of the Hassuna Samara culture. This study presents the results regarding one of the first detailed archaeometric investigations carried out for the Late Neolithic ceramic findings unearthed from Şah Valley (Şırnak province, Turkey). The ceramics were initially characterized by means of portable X-ray florescence (p-XRF) and X-ray diffraction (XRD) in order to enlighten the chemical and mineralogical features of the samples, respectively. The results indicated use of calcareous raw material sources and a low firing temperature range (ca. 700-800oC). The potsherds were also investigated through petrography which showed the presence of quartz, opaque minerals, plagioclase and biotite as the minerals, and clay, claystone and marl rock contents as the rock types for the samples, in general. Fourier transformed infrared (FTIR) spectroscopy was additionally applied for the potsherds. This complementary technique provided information about the vibrations of the chemical bands in the ceramics which displayed the characteristic bond vibrations of decisive minerals in the ceramic fabrics, such as calcite, clay minerals and quartz. Considering the whole archaeometric data, it can be deduced that the Neolithic ceramics of the Şah Valley have been subjected to low firing temperatures which could be assigned to a basic production procedure presumably claiming daily-use wares.
INSIGHT INTO THE EFFECT OF TI/ZR OXIDE HYBRID PARTICLES ON DENTAL COMPOSITES: PARTICLE SYNTHESIS AND CHARACTERIZATION AND THE MECHANICAL BEHAVIOR OF COMPOSITES
Authors: YEŞİL ACAR Zerin
Published: April 2023

Hybrid particles were synthesized with sol–gel-based hydrothermal method using alkoxide precursors, and the usability of these particles in dental composites was investigated. First, the effects of varying Ti/Zr and nacid/ nalkoxide ratios on the crystal and microstructure of the synthesized particles (Ti, Zr) hybrids were investigated. X-ray diffraction (XRD), a particle size and a surface charge analyzer, thermogravimetric analysis (TGA), Brunauer–Emmett–Teller (BET) analysis, and Fourier transform infrared (FTIR) analysis were used to reveal the structural parameters. ZTit-1, ZTit-4, and ZTit-6 particles were crystalline, while ZTit-2, ZTit-3, and ZTit-5 particles were amorphous. The zeta potential of the most stable ZTit-4 particle was 43.33 mV. ZTit-3 particles had the highest surface area and ZTit-5 particles had the highest micropore area. The presence of Ti/Zr oxide and titanate structures was determined by FTIR analysis. In the next step of the study, the mechanical behavior of the synthesized Ti/Zr-based hybrid particles in the dental organic matrix was investigated. The flexural, compressive strengths, and microhardness of the ZTit-4 composite with optimal flowability were 175±16.1 MPa, 242±7.8 MPa, and 32.9 Hv.