bluuebunny/crossref_metadata_2025 huggingface dataset:
New alternative for adsorption of 2,4-dichlorophenoxyacetic acid herbicide (2,4-D)
Authors: Rimoli Michelle Ferreira da Silva , Nogueira Roberta Martins , Castro Pryscila Machado de , Merlo Aloir Antônio , Sinhorin Adilson , Kerkhoff Jacqueline , Ferrarini Stela Regina , Pires Evaldo Martins
Published: August 2023

The adsorptive capacity of charcoal from the husk of the brazil nut fruit, called “ouriço” (the hard ball with nuts inside) for the herbicide dichlorophenoxyacetic acid (2,4-D) was evaluated. Activated carbons were produced from the brazil nut in a tubular oven at 800 °C and activated with CO2 or water steam. The specific surface area was determined by the Brunauer, Emmett and Teller (BET) method, demonstrating the mean density of micropores. Analysis of N2 adsorption/desorption isotherms was undertaken and the morphology of activated carbons was visualized by Scanning Microscopy (SEM). The activated carbons were successfully obtained and had a specific surface area of 395 m2.g-1 and 401 m2.g-1 after activation with either CO2 or water steam, respectively. The highest pore mean density occurred with a diameter of 1.17 nm for carbons activated in both atmospheres. The graph of the adsorption/desorption isotherms of N2 showed Type I isotherms, regardless of the activation atmosphere. The SEM analysis showed that, for both activation atmospheres, pore formation occurred in the shape of uniform honeycomb craters. Adsorption kinetics followed the pseudo-second order model, indicating chemisorption. Regardless of the activation atmosphere, the activated carbon from the brazil nut “ouriço”, was highly efficient for 2,4-D adsorption.
DA GLOBALIZAÇÃO DE INFECÇÕES/DOENÇAS AO ESTIGMA: O HIV AO SUL DO EQUADOR
Authors: Silva Jeziel Silveira , Pimentel Ivan Ignácio
Published: August 2023

Considerando que diversas doenças/infecções assolam a população brasileira desde a chegada dos portugueses ao “novo continente”, o presente trabalho tem como objetivo demonstrar a forte correlação entre a aceleração do processo de globalização e a chegada de diversas pandemias ao Brasil, em especial o HIV/AIDS, doença que na década de 1980 era chamada de “peste gay” e foi responsável pela estigmatização da homossexualidade masculina. Ao longo do tempo, muitas conquistas foram obtidas pelos movimentos sociais, como o tratamento do HIV e a difusão de informações legítimas sobre o HIV/AIDS, uma vez que a infecção/doença impacta toda a sociedade. Apesar disso, dias difíceis tomam conta do país, ameaçando a existência do SUS e a oferta gratuita de medicamentos pré e pós-exposição ao vírus. Como materiais e métodos, destacamos a revisão bibliográfica com a presença de triangulação de métodos, observando os olhares dos pesquisadores sobre o fenômeno a partir de mais de um ângulo, método de revisão de literatura de cunho sistemático, coletando dados e salientando evidências a respeito do cenário do HIV/AIDS no Brasil e, por fim, traçamos uma análise documental de cunho historiográfico que ampara esta pesquisa e contribui de forma substancial para a construção teórico-metodológica deste artigo. Logo, como resultados, percebe-se que desde o Brasil Colônia a globalização de doenças tem acometido milhares de pessoas e que, ainda hoje, após 40 anos do primeiro caso de HIV/AIDS, a culpabilidade tem sido profundamente direcionada para determinados grupos sociais.
Guidelines for the Development of Traditional Cake Products Business of Entrepreneurs in Trang Province
Authors:   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakorn., Butkrut Jatuporn , Kee-ariyo Chayapat ,   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakorn.
Published: August 2023

The purposes of this research were : 1) to study the conditions of business operation of traditional cake products of entrepreneurs in Trang Province.2) To study the problems in business operation of traditional cake products of entrepreneurs in Trang Province. 3) To compare the level of problems in business operations of traditional cake products of entrepreneurs in Trang Province classified by business conditions and, 4) to present guidelines for the development of business operations of traditional cake products of entrepreneurs in Trang Province. The population is 25 traditional cake products business entrepreneurs in Trang Province. The research instrument was a questionnaire. The statistics used for data analysis were frequency, percentage, mean, standard deviation. One-way ANOVA and analyze descriptive data. The results showed that: 1) The results showed that: 1) the traditional type of cake in the business is three flavor cakes, which has been in business for more than 31 years with a marketing channel as a point of sale. The business has an estimated daily production about 51-100 boxes or more than 151 boxes, earning approximately about 100,001-200,000 baht from product distribution and most of the businesses are located in the commercial area in the city. 2) Entrepreneurs have a high level of business problems. When considering each aspect in descending order, it was found that the aspect with the highest mean was finance, followed by sales, and the least was management.3) Comparison of the level of problems in business operations of traditional cake products of entrepreneurs in Trang province classified by business conditions found that entrepreneurs with different business conditions had no different problems in operating the traditional cake products business in Trang Province, except for entrepreneurs with a period of business and the location of the businesses were statistically different at the .05 level., and 4) the guidelines for the development of traditional cake products business of entrepreneurs in Trang Province are entrepreneurs should pay attention to the selection of raw materials that are of constant quality. There should be more beautiful cake designs and more variations. There should be an online ordering channel, such as ordering through the website or an application and has a delivery service. There should be a concise accounting of income and expenses, and sales are monitored regularly. Employees are encouraged to be professional and able to sustain and maintain their own business values.
The Development of Video Program on Fruit Vegetable Carving and Banana Leaf Crafting
Authors:   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakorn., Chantakul Sukunya , Hongrattanavorakit Sakarin ,   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakorn., Aitsarasuchip Khajan ,   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakorn., Suksala Somprastana ,   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakorn.
Published: August 2023

The purposes of this study are to 1) development of video program on fruit vegetable carving and banana leaf crafting, 2) find the effectiveness of practical fruits, vegetable carving and banana leaf teaching to be efficient according to the criteria 80/80, and 3) to study the students' satisfaction towards video media of practical fruits, vegetable carving and banana leaf teaching. The sample group used were 35 2nd-year undergraduate students Department of Home Economics Business Administration, Faculty of Home Economics Technology from the Rajamangala University of Technology. Then divided into groups to estimate, assessment form was used for media quality as well as student performance assessment form and also satisfaction assessment form was used, data were analyzed using descriptive statistics and Inferential statistics. The results showed that video media of practical teaching fruits, vegetable carving and banana leaf from 4 videos including 1. Vegetable carving 2. Fruits scooping and peeling 3. Petal folding from banana leaf and 4.Making ware from banana leaves. The overall media quality in terms of content is very good, with an average score of 4.80, The overall video quality is in very good condition an average score of 4.62, which is effective 81.57/89.55 every performance exceeds the threshold which performs above the set regulative specified criteria of 80/80, the students' satisfaction towards video media of practical teaching fruits, vegetable carving and banana leaf overall, all subjects were in the highest criteria with an average of 4.72.
Investigation of Problems Regarding Safety Management and Instruction of Engineering Workshop and Laboratory Practices of Public Higher Education Institutions
Authors:   Faculty of Business and Industrial Development, King Mongkut’s University of Technology North Bangkok, Woraphiwut Adisak
Published: August 2023

The research aims and objectives are 1) to study the problems regarding safety management of students in respect of workshop and laboratory practices in public higher education institutions; 2) to explore the problems of laboratory-based and workshop-based practicum instruction; and 3)to apply the information obtained as development guidelines to improve workshop and laboratory efficiency. The Delphi technique was used to achieve consensus from 20 expert participants. Research instruments included interview forms and questionnaires while statistical measures for data analysis involved frequency distribution, percentage, median and interquartile range calculation. To categorize the issues, the problems related to managing safety and teaching engineering workshop and laboratory courses were found to consist of 7 main components and 31 subcomponents as follows: 1) Workshop and Engineering Laboratory Design, with 3 subcomponents; 2) Machine Shop Safety, Electrical Safety and Fire Safety, with 10 subcomponents; 3) Internal Environment for Workshop and Laboratory Practices, with 5 subcomponents; 4) Facilities and Equipment for Laboratory and Workshop Practices, comprising 2 subcomponents; 5) Operations Facility Management and Green Occupations, with 3 subcomponents; 6) Roles and Responsibilities for Operational Safety, containing 4 subcomponents; and 7) Curriculum Development and Learning Management, with its 6 subcomponents.
School admissions and educational justice: Parents' moral dilemmas facing the new Chilean school admission system
Authors: Hernández Macarena , Carrasco Alejandro , Bonilla Angélica , Honey Ngaire
Published: August 2023

In the context of the increased interest in social justice within education policy debates, this article addresses the new justice-oriented school admission system implemented in Chile. Considering the critical role of parents in education policy, we explore families’ negotiations about the new school admission system, focusing on the moral dilemmas they experience when confronted with changes in the rules that organize the distribution of school seats and the notions of educational justice they adhere to. We draw on interviews with 80 families from different social classes and belonging to five regions of Chile who were choosing a school under the new school admission system. Our findings underline that—while families tend to agree with the principle of equal formal opportunities in the school admission field—the reform brings in a set of moral dilemmas and competing notions of justice that encompass its different components. Based on these findings, we shed light on the distance between policy intention and interpretation, and between abstract conceptualizations of justice in educational policies and what counts as just policies in families’ views. In addition, we outline a set of implications for justice-oriented reforms worldwide.
Experiências individuais, sociais e raciais com ações afirmativas nas universidades brasileiras: Revisão de escopo
Authors: Vieira Kênia Eliber , Albino Laura Aparecida Martins , Dell’Agli Betânia Alves Veiga , Caetano Luciana Maria
Published: August 2023

As ações afirmativas nas universidades brasileiras vêm promovendo a convivência de diferentes grupos sociais e étnicos/raciais. Esta revisão de escopo teve como objetivo identificar, analisar e sintetizar os estudos sobre experiências individuais, sociais e raciais do público envolvido com as ações afirmativas no ensino superior. A busca nas bases de dados Scielo, BVS – saúde, LILACS, BVS-PSI, EBSCO, APA/PsycNet, MEDLINE/PubMed, ProQuest-ERIC, Web of Science, Scopus, Embase (Elsevier), com delimitação temporal dos últimos 10 anos resultou na seleção de 46 artigos. Foram categorizados, com o auxílio do software Iramuteq, quatro classes temáticas: as relações interpessoais, a representatividade, a identidade racial e as dificuldades e os facilitadores da permanência no ambiente acadêmico. A convivência com a diversidade proporcionou a quebra das barreiras e estereótipos sobre grupos diferentes e favoreceu transformações positivas na representatividade e na identificação racial e social. Os discursos dos próprios envolvidos com a política revelaram estratégias e possibilidades institucionais para a permanência e bem-estar dos estudantes.
Atividade antimicrobiana produzida por fungos filamentosos isolados das águas do Baixo Rio Tapajós, Pará, Brasil
Authors: Bentes Vanessa dos Santos , Santana Marcos Diones Ferreira , Fernandes Graciene Do Socorro Taveira , Dos Santos Taides Tavares , Canto Eveleise Samira Martins
Published: August 2023

Estudos em ambientes aquáticos amazônicos são incipientes, no que se refere à investigação de antimicrobianos produzidos por fungos filamentosos. Este trabalho avaliou qualitativamente o potencial antimicrobiano de fungos da Bacia do Baixo Rio Tapajós, Pará, Brasil. A coleta foi realizada em diferentes pontos da Bacia do Baixo Rio Tapajós, de onde foram selecionados quinze fungos. As cepas foram submetidas à fermentação em meio de cultura Caldo Batata Dextrose e filtradas após 15 dias de incubação. Utilizando o método Cup Plate, foram adicionadas alíquotas de 100 μL do caldo bruto em poços (6 mm de diâmetro) perfurados em placas de Petri (90 mm de diâmetro) contendo meio para cultivo específico das cepas ATCC utilizadas nos testes (Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 e Candida albicans ATCC 60193). Para validação da técnica, foram utilizados como controle positivo os antibióticos comerciais específicos contra as bactérias, assim como para a levedura. Para controle negativo, utilizou-se o solvente da solução padrão, sem adição dos antibióticos utilizados contra as cepas testadas. Aspergillus sp. BBRT 01 se destacou por apresentar ação antimicrobiana para as três cepas de micro-organismos testadas, além dessa, Paecilomyces sp. BBRT 11, Penicillium sp. BBRT 12 e Penicillium sp. BBRT 13 apresentaram ação antimicrobiana contra S. aureus. Fusarium sp. BBRT 09 apresentou atividade contra C. albicans e S. aureus. Diante dos resultados, salienta-se que os fungos filamentosos da Bacia do Baixo Rio Tapajós apresentaram potencial para bioprospectar substâncias bioativas e representam um horizonte para as pesquisas envolvendo os rios amazônicos.
Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex‐ and age‐dependent manner in mice
Authors: Arullampalam Prakash , Essers Maria C. , Boukenna Mey , Guichard Sabrina , Rougier Jean‐Sébastien , Abriel Hugues
Published: August 2023

TRPM4 is a calcium‐activated, voltage‐modulated, nonselective ion channel widely expressed in various cells and tissues. TRPM4 regulates the influx of sodium ions, thus playing a role in regulating the membrane potential. In the heart, TRPM4 is expressed in both cardiomyocytes and cells of the conductive pathways. Clinical studies have linked TRPM4 mutations to several cardiac disorders. While data from experimental studies have demonstrated TRPM4's functional significance in cardiac physiology, its exact roles in the heart have remained unclear. In this study, we investigated the role of TRPM4 in cardiac physiology in a newly generated Trpm4 knockdown mouse model. Male and female Trpm4 knockdown (Trpm4−/−) and wild‐type mice of different ages (5‐ to 12‐ week‐old (young) and 24‐week‐old or more (adult)) were characterized using a multimodal approach, encompassing surface electrocardiograms (ECG), echocardiography recordings, ex vivo ECGs in isolated heart, endocardial mappings, Western blots, and mRNA quantifications. The assessment of cardiac electrophysiology by surface ECGs revealed no significant differences between wild‐type and Trpm4−/− young (5‐ to 12‐week‐old) mice of either sex. Above 24 weeks of age, adult male Trpm4−/− mice showed reduced heart rate and increased heart rate variability. Echocardiography revealed that only adult male Trpm4−/− mice exhibited slight left ventricular hypertrophic alterations compared to controls, illustrated by alterations of the mitral valve pressure halftime, the mitral valve E/A ratio, the isovolumetric relaxation time, and the mitral valve deceleration. In addition, an assessment of the right ventricular systolic function by scanning the pulmonary valve highlighted an alteration in pulmonary valve peak velocity and pressure in adult male Trpm4−/− mice. Endocardial mapping recordings showed that applying 5 μM of the new TRPM4 inhibitor NBA triggered a third‐degree atrioventricular block on 40% of wild‐type hearts. These results confirm the key role of TRPM4 in the proper structure and electrical function of the heart. It also reveals differences between male and female animals that have never been reported. In addition, the investigation of the effects of NBA on heart function confirms the role of TRPM4 in atrioventricular conduction.
A supervised machine-learning approach for the efficient development of a multi method (LC-MS) for a large number of drugs and subsets thereof: focus on oral antitumor agents
Authors: Kehl Niklas , Gessner Arne , Maas Renke , Fromm Martin F. , Taudte R. Verena
Published: August 2023

Objectives

Accumulating evidence argues for a more widespread use of therapeutic drug monitoring (TDM) to support individualized medicine, especially for therapies where toxicity and efficacy are critical issues, such as in oncology. However, development of TDM assays struggles to keep pace with the rapid introduction of new drugs. Therefore, novel approaches for faster assay development are needed that also allow effortless inclusion of newly approved drugs as well as customization to smaller subsets if scientific or clinical situations require.

Methods

We applied and evaluated two machine-learning approaches i.e., a regression-based approach and an artificial neural network (ANN) to retention time (RT) prediction for efficient development of a liquid chromatography mass spectrometry (LC-MS) method quantifying 73 oral antitumor drugs (OADs) and five active metabolites. Individual steps included training, evaluation, comparison, and application of the superior approach to RT prediction, followed by stipulation of the optimal gradient.

Results

Both approaches showed excellent results for RT prediction (mean difference ± standard deviation: 2.08 % ± 9.44 % ANN; 1.78 % ± 1.93 % regression-based approach). Using the regression-based approach, the optimum gradient (4.91 % MeOH/min) was predicted with a total run time of 17.92 min. The associated method was fully validated following FDA and EMA guidelines. Exemplary modification and application of the regression-based approach to a subset of 14 uro-oncological agents resulted in a considerably shortened run time of 9.29 min.

Conclusions

Using a regression-based approach, a multi drug LC-MS assay for RT prediction was efficiently developed, which can be easily expanded to newly approved OADs and customized to smaller subsets if required.
Gorenstein complexes over formal triangular matrix rings
Authors: Kong Fangdi , Wu Dejun
Published: August 2023

Let 𝐴 and 𝐵 be rings and 𝑈 a

(
B
,
A
)

(B,A)

-bimodule.
The Gorenstein projective, injective and flat complexes over the formal triangular matrix ring

T
=

(

A

0

U

B

)

T=\bigl{(}\!\begin{smallmatrix}A&0\\
U&B\end{smallmatrix}\!\bigr{)}

are explicitly described.
These statements extend some earlier results of Enochs, Cortés-Izurdiaga, Torrecillas, Zhang and Mao in this direction.
Moho depth estimation of northern of East African Rift System
Authors: Alemu Eyasu
Published: August 2023

The northern part of the East African Rift System is characterized by depleted Moho depth and thermally thinned lithosphere. This research aims to determine the Moho depth of the study area through non-linear gravity inversion and cross-validation with seismic Moho estimates. The study utilized gravity data to obtain the gravity anomaly of the Moho interface, a topographic grid for removing topographic effects, a crustal model to determine total sediment thickness and its gravitational effect, and seismic Moho depth for constraining the forward model and cross-validation. The estimated Moho depth of the study area ranges between 5 km (in the Indian Ocean) to 45 km (in the Ethiopian Highlands), with slight variation compared to seismic Moho relief. This is because the reference level, calculated for the thinner part of the study region, underestimates the entire area. Upwelling magma in the Eastern branches of the EARS may also incur slight variation in the estimated Moho depth; rifting, volcanism, melt intrusion, magmatic uplift, and tectonic setting all influence the Moho depth of the study area. Furthermore, reverberations affect most seismic Moho estimations in the region. The slight variation can be mitigated by improving the gravity network for accurate validation and precise heat flow measurement to correctly identify magmatic anomalies and density contrasts. Additionally, applying reverberation removal techniques in the study region could improve seismic Moho estimation.
The deal.II Library, Version 9.5
Authors: Arndt Daniel , Bangerth Wolfgang , Bergbauer Maximilian , Feder Marco , Fehling Marc , Heinz Johannes , Heister Timo , Heltai Luca , Kronbichler Martin , Maier Matthias , Munch Peter , Pelteret Jean-Paul , Turcksin Bruno , Wells David , Zampini Stefano
Published: August 2023

This paper provides an overview of the new features of the finite element library deal.II, version 9.5.
Effects of different profiled pins used in friction stir welding of Al 6061 T6
Authors: Gündoğdu İş Emine , Koçak Kadir , Basar Zeynep Sueda , Yavuz Yağızer , Topuz Polat
Published: August 2023

In this study, Al 6061 T6 alloy was joined by friction stir welding method with the same parameters using with different profiled pins. As a result of the experiments carried out, the samples were subjected to metallographic examination, hardness measurements, tensile test and bending test. As a result of the examinations carried out, changes in welding performances were determined with the change of pin profiles. As a result of these changes, it was determined that the pin profile suitable for the applied welding parameters was pyramid. It has been concluded that in the use of triangular profile pins, the welding parameters in question should be higher, and the most important reason for this is that the stir zone is larger.
Nietzsche und der lange Flug des „guten Europäers“
Authors: Zellini Susanna
Published: August 2023

Nietzsche and the Long Flight of the “Good European”. The question of “the good European,” as Nietzsche conceives it, refers to a complex process of cultural transformation that starts from the critical relationship toward the European Christian heritage. The three volumes discussed in this review single out three different aspects of this cultural process: a “new Enlightenment,” which refers to the gradual liberation from the European tradition “in search of good Europeans” (Crescenzi / Gentili / Venturelli 2017), the early twentieth-century debate around “European identity” (Crescenzi / Gentili / Venturelli 2018), in which the good European takes on a precise role, and contemporary Europe and the current relevance of the good European (Brusotti / McNeal / Schubert / Siemens 2020). This review discusses and reflects critically on these three volumes, examining how they contribute to contemporary debates about Nietzsche and the question of a European culture.
Intelligent Repair Method for Archival Videos Based on the Super-SloMo Technology
Authors: Li Hui
Published: August 2023

Due to equipment limitations in the early shooting of video files, and the damage and aging in the later file storage process, some historic video materials in video archives can easily suffer from defects such as poor action coherence. This paper proposes an intelligent enhanced repair method for archival videos. The method first obtains the frame rate of the input video, then calculates the dynamic coefficient of the video according to the frame rate and duration number, uses the artificial intelligence algorithm Super-SloMo technology to fix the problematic digital video to the required frame rate, improves the video's dynamic coefficient, and finally achieves the purpose of getting the enhanced repaired digital copies of the original video materials from video archives. This paper also proposes an intelligent enhanced repair prototype system based on the method. The experiment shows that the enhanced repair effect is effective and improves the clarity and coherence of the video. Users get more coherent copies of historic video materials. This solves the problem of the poor perception caused by the loss of frames, preserves the original information, and makes the information obtained from archival videos intuitive.
A humoros reklámok napos és sötét oldala: A humoros reklám potenciális hatásainak szakirodalmi áttekintése
Authors: Babinszki Emese , Balázs Katalin
Published: August 2023

A TANULMÁNY CÉLJA
A tanulmány célja a humoros reklámok szakirodalmának áttekintése, aminek apropóját a magyar szakirodalomban még kévéssé tárgyalt humorelmélet, a Szelíd Támadás Elmélet (The Benign Violation Theory) (McGraw & Warren 2010) adja. A célunk a klasszikus humormodellek, a humoros reklámok modellek és az új elmélet integrálása.
ALKALMAZOTT MÓDSZERTAN
A tanulmányban az általános humorelméletek és a humoros reklámokra vonatkozó tanulmányok elméletei kerültek összefoglalásra. Az áttekintés újdonsága a humor potenciális negatív hatásainak kibővítése. A feldolgozott anyagok között klasszikus elméletek és frissebb publikációk is megjelennek.
LEGFONTOSABB EREDMÉNYEK
A humor általános elméleteiben és tipológiáiban már kezdetektől megjelentek a humor offenzív formái, és a humor alkalmazásának negatív következményei. Bár a humoros reklámok vizsgálatai sok esetben mutattak negatív hatásokat is, a humoros reklámok hatásmechanizmusára vonatkozó modellek szinte kizárólag a pozitív hatásokat írták le. A humorra vonatkozó újabb kutatások azonban rámutatnak arra, hogy a humor vizsgálata esetén a negatív hatások figyelembevétele kifejezetten fontos lenne. Ez kiemelten igaz a humor offenzív típusai esetében. A pozitív és a negatív hatások integrált vizsgálata a következő logikus lépést jelenthetné a humor hatásának tudományos vizsgálatában.
GYAKORLATI JAVASLATOK
A humor sokat vizsgált pozitív hatásain túl a negatív aspektusoknak is hangsúlyt kell kapniuk a humoros reklámok vizsgálataiban. A humoros reklámok hatásainak vizsgálata esetén egy integrált szemlélet előrevivő lenne, mert a humoros reklám nemcsak figyelemfelkeltő, de sértő, megbotránkoztató is lehet. A kiváltott hatás függ a reklám típusától, a márkától és a kultúra normáitól is.  A hatásvizsgálatok során mind pozitív mind negatív érzéseket keltő humor típusokat alkalmazni kellene. Így válhatna elérhetővé az a cél, hogy az eddigieknél komplexebb módon modellezzék a reklámok hatását. Ez pontosabb predikcióhoz vezethetne egy-egy reklám vagy egy marketingkampány tervezése során.
Le forum de coélaboration de connaissances : source d’inspiration et de soutien à la rédaction d’un récit en cinq temps aux 2e et 3e cycles du primaire
Authors: Thériault Pascale , Allaire Stéphane , Nadeau-Tremblay Sophie , Gaudreault Mélanie , Gagnon Vincent
Published: August 2023

Le Forum de coélaboration de connaissances (FCC) est un outil de communication asynchrone qui permet l’appropriation de connaissances par la lecture et l’écriture de notes exprimant la pensée (Catel, 2001). L’article présente les résultats de l’apport de ce dispositif d’écriture collaborative pour soutenir l’énonciation d’idées lors de la rédaction individuelle d’un récit en cinq temps chez des élèves du primaire. Ces résultats, obtenus dans le cadre d’une recherche-action, tendent à mettre en lumière le potentiel d’une écriture collaborative soutenue par le FCC pour fournir des idées aux élèves lorsqu’ils sont ensuite soumis à une tâche individuelle d’écriture.
La causerie à la maternelle 4 ans : une activité toute désignée pour soutenir le développement du langage oral
Authors: Fortin Majorie , Thériault Pascale
Published: August 2023

Les enfants qui fréquentent la maternelle 4 ans temps plein en milieu défavorisé (TPMD) bénéficient d’une structure éducative qui leur permet de développer, entre autres, leurs habiletés langagières. Dans ce contexte, l’activité pédagogique de la causerie présente plusieurs caractéristiques qui favorisent le développement du langage oral. Cependant, les stratégies d’intervention à privilégier lors de l’animation de cette activité semblent parfois peu connues des enseignantes[1]. Cette étude, à laquelle ont participé trois enseignantes de la maternelle 4 ans TPMD, dresse le portrait des différentes stratégies d’intervention pouvant soutenir le développement du langage oral lors de l’animation de la causerie dans ce contexte.

 

[1] Le terme « enseignante » est utilisé considérant la place importante du personnel féminin à l’éducation préscolaire.
Comment soutenir les directions d’établissement novices dans leur développement professionnel? : présentation d’un programme d’insertion professionnelle créé et expérimenté dans un centre de services scolaires
Authors: Gagnon Brigitte , Lachapelle Dominique
Published: August 2023

Les directions d’établissements scolaires (DÉ) exercent un rôle névralgique en assumant diverses responsabilités au regard de la réussite éducative. Pour une direction novice, l’exercice de la fonction comporte de nombreux défis et nécessite un soutien bienveillant. C’est pourquoi il importe que les centres de services scolaires, en complément à la formation universitaire obligatoire, puissent leur offrir des dispositifs d’insertion professionnelle leur permettant de se développer et de construire leur nouvelle identité professionnelle. Notre article présente la création d’un programme d’insertion professionnelle dans un centre de services scolaire, les retombées observées et les conditions gagnantes pour en assurer la pérennité.
Land Concessions and Postwar Conflict in Laos
Authors: Baird Ian G.
Published: August 2023

Although it is commonly thought that the war in Laos ended in 1975 when the communist Pathet Lao took over the country, in fact the takeover stirred up considerable military and political opposition, leading to civil war. For a variety of reasons, the conflict diminished in the 1990s and 2000s. The improved security situation allowed the government to adopt a new policy allocating large-scale land concessions for use in developing commercial plantations. These concessions inflicted social and environmental violence on the people who lost their land. These two types of violence in Laos, war and dispossession, are linked more closely than is generally recognized.
Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b‐mediated chromatin demethylation
Authors: Phan Quan M , Salz Lucia , Kindl Sam S , Lopez Jayden S , Thompson Sean M , Makkar Jasson , Driskell Iwona M , Driskell Ryan R
Published: August 2023

Dermal Fibroblast Progenitors (DFPs) differentiate into distinct fibroblast lineages during skin development. However, the epigenetic mechanisms that regulate DFP differentiation are not known. Our objective was to use multimodal single‐cell approaches, epigenetic assays, and allografting techniques to define a DFP state and the mechanism that governs its differentiation potential. Our initial results indicated that the overall transcription profile of DFPs is repressed by H3K27me3 and has inaccessible chromatin at lineage‐specific genes. Surprisingly, the repressive chromatin profile of DFPs renders them unable to reform the skin in allograft assays despite their multipotent potential. We hypothesized that chromatin derepression was modulated by the H3K27me3 demethylase, Kdm6b/Jmjd3. Dermal fibroblast–specific deletion of Kdm6b/Jmjd3 in mice resulted in adipocyte compartment ablation and inhibition of mature dermal papilla functions, confirmed by additional single‐cell RNA‐seq, ChIP‐seq, and allografting assays. We conclude that DFPs are functionally derepressed during murine skin development by Kdm6b/Jmjd3. Our studies therefore reveal a multimodal understanding of how DFPs differentiate into distinct fibroblast lineages and provide a novel publicly available multiomics search tool.
Robust dimethyl‐based multiplex‐DIA doubles single‐cell proteome depth via a reference channel
Authors: Thielert Marvin , Itang Ericka CM , Ammar Constantin , Rosenberger Florian A , Bludau Isabell , Schweizer Lisa , Nordmann Thierry M , Skowronek Patricia , Wahle Maria , Zeng Wen‐Feng , Zhou Xie‐Xuan , Brunner Andreas‐David , Richter Sabrina , Levesque Mitchell P , Theis Fabian J , Steger Martin , Mann Matthias
Published: August 2023

Single‐cell proteomics aims to characterize biological function and heterogeneity at the level of proteins in an unbiased manner. It is currently limited in proteomic depth, throughput, and robustness, which we address here by a streamlined multiplexed workflow using data‐independent acquisition (mDIA). We demonstrate automated and complete dimethyl labeling of bulk or single‐cell samples, without losing proteomic depth. Lys‐N digestion enables five‐plex quantification at MS1 and MS2 level. Because the multiplexed channels are quantitatively isolated from each other, mDIA accommodates a reference channel that does not interfere with the target channels. Our algorithm RefQuant takes advantage of this and confidently quantifies twice as many proteins per single cell compared to our previous work (Brunner et al, PMID 35226415), while our workflow currently allows routine analysis of 80 single cells per day. Finally, we combined mDIA with spatial proteomics to increase the throughput of Deep Visual Proteomics seven‐fold for microdissection and four‐fold for MS analysis. Applying this to primary cutaneous melanoma, we discovered proteomic signatures of cells within distinct tumor microenvironments, showcasing its potential for precision oncology.
Functions of Parents Homeschooling Their Children: The Case of Lithuania
Authors: Naidaitė Edita , Stasiūnaitienė Eglė
Published: August 2023

The article presents the most illustrative results of a broader empirical study carried out in Lithuania in 2021–2022. The aim is to answer the question of what the functions of parents are and how the child’s education is organised in the case of homeschooling. The research data were collected using a semi-structured interview method and were processed using content analysis. The data were analysed under the topic “Functions of parents homeschooling their children”. The topic combines the following seven sub-topics: planning and organising the educational process, selecting/developing educational content, designing learning environments, ensuring a safe learning environment, recording learning achievements, assessing learning achievements, and ensuring socialisation. The research involved ten informants (five parents homeschooling their children and five heads of educational institutions) selected by criterion sampling. To summarise the results of the empirical research, it should be highlighted that when parents choose to homeschool their children, they essentially take over the main function of educational institutions and become responsible for the organisation of the entire educational process. The child is involved in the planning of the educational process; the individual needs of the child are better taken into account, and the child’s autonomy is encouraged. The curriculum and schedule are flexible, based on the child’s acquired knowledge, competences, and skills rather than on the number of lessons. Educational environments are constantly changing and are usually chosen by the child. Parents who participated in the study have identified difficulties in analysing the documents of the education system and the lack of access to the electronic diary. The heads of educational institutions have expressed doubts about the pedagogical preparation of parents to homeschool their children and to ensure purposeful socialisation; however, the parents have noted that socialisation is sufficient and takes place according to the child’s individual needs. In the authors’ opinion, the research carried out raises topical issues for discussion and the initiation of new research in this area, with the aim of better understanding the context of the phenomenon of homeschooling.
Germanium (IV) Complexes with Gluconic Acid as Effectors of Penicillium tardum and Eupenicillium erubescens α-L-Rhamnosidases
Authors: Gudzenko O.V. , Borzova N.V. , Varbanets L.D. , Seifullina I.I. , Martsinko О.E. , Chebanenko О.A.
Published: August 2023

α-L-Rhamnosidase (α-L-rhamnoside-rhamnohydrolase EC 3.2.1.40) showing specificity for terminal α-1,2-, α-1,4- and α-1,6-linked rhamnose residues, which often present in glycoconjugates and synthetic glycosides, can be successfully used in biotechnology for the hydrolysis of rhamnopyranoside residues present in some bioflavonoids, glycoproteins, glycolipids, and other glycoconjugates. Previously, we have shown that a significant part of the coordination compounds of various metals act as effectors of the activity of α-L-rhamnosidases. The aim of this investigation was to study the effect of a number of newly synthesized coordination compounds of Ge(IV) and Ba(II), (Co(II), Ni(II), Cu(II), Zn(II) with gluconic acid on the activity of Penicillium tardum and Eupenicillium erubescens α-L-rhamnosidases. Methods. The objects of the study were Penicillium tardum and Eupenicillium erubescens α-L-rhamnosidases. α-L-Rhamnosidase activity was determined by the Davis method using naringin as a substrate. Coordination compounds Ge(IV) and Ba(II), Co(II), Ni(II), Cu(II) ,and Zn(II) with gluconic acid were used as enzyme activity modifiers. The synthesized complexes correspond to the formulas [М(H2O)6][Ge2(OH)2(C6H8O7)2]·nH2O (М = Ba(1), n=2; Co(2), n=4; Ni(3), n=4; Cu(4), n=4; Zn(5), n=3). Results. The effect of coordination compounds 1-(5) on the activity of α-L-rhamnosidase in two strains of Penicillium tardum and Eupenicillium erubescens was studied depending on the exposure time and concentration of the effector. It was shown that compound (3) at a concentration of 0.01% (1 h incubation) led to a slight (by 5%) increase in the activity of P. tardum α-L-rhamnosidase. Compound 1 at a concentration of 0.1% led to a decrease in the activity of P. tardum α-L-rhamnosidase by 29% during the first hour, and after 24 h of incubation, a decrease in the inhibitory effect to 15% was noted. Compounds 2 and (4) activated the enzyme by 9-39% at 1h exposure. At a concentration of 0.1% and exposure time of 1 h, compound 1 increased the activity of E. erubescens α-L-rhamnosidase by 80%, while at a decrease in concentration to 0.01%, the activity increased only by 29%. In general, it should be noted that in most cases, an increase in the duration of incubation up to 24 h led to a decrease in the level of activation (or inhibition) and a return to the control values of enzyme activity. Conclusions. The variety of effects of metal coordination compounds on the activity of enzymes, depending on the nature of the cation and the origin of the enzyme, has been established. The involvement of Ba(II) had the greatest activating effect on the activity of E. erubescens α-L-rhamnosidase compared to other metals.
A cidade: o cotidiano de Porto Alegre nas crônicas de Roque Callage (1925-1930) Volume 2
Authors: Murari Luciana
Published: August 2023

Filho de um imigrante italiano e de mãe brasileira, Roque Callage nasceu em 1888, em Santa Maria, cidade em que realizou suas primeiras incursões pela imprensa. Esse foi um de seus principais espaços de atuação, tendo colaborado com diversas publicações, do interior do Rio Grande do Sul ao Rio de Janeiro. Escreveu também um dicionário de termos gauchescos e duas obras de militância política, engajando-se nas revoluções de 1923 e de 1930. Desenvolveu ainda uma carreira literária, principalmente como escritor de contos regionalistas. Tornou-se célebre em Porto Alegre a partir de março de 1925, quando passou a assinar a coluna diária “A Cidade”, no jornal Diário de Notícias. Dedicada aos mais diversos temas de interesse público, a coluna acompanhou as muitas facetas da vida cotidiana na capital, que passava então por um período de reformas urbanas e de elevadas expectativas de modernização.
Neue Wege der Hochschulgovernance
Authors: Bassen Alexander , Roosendaal Hans E. , Zalewska-Kurek Kasia , Sporn Barbara , Küpper Hans-Ulrich , Weber Wolfgang
Published: August 2023

Das Ende der Gründungsphase der Fakultät Wirtschafts- und Sozialwissenschaften mit der Integration der bis dahin selbstständigen Hamburger Universität für Wirtschaft und Politik (HWP) sowie der bisherigen Fachbereiche Wirtschaftswissenschaften und Sozialwissenschaften der Universität Hamburg war Anlass zu einem wissenschaftlichen Symposium zur Hochschulgovernance mit hochkarätiger Besetzung. Ziel war es, unterschiedliche Management-Modelle, vor allem aus dem europäischen Ausland, einander gegenüberzustellen und diese sowohl aus einer erfahrungsbasierten Leitungsperspektive als auch unter wissenschaftlich-analytischen Sichtweisen zu analysieren und zu bewerten. Ein besonderer Aspekt lag auf dem für alle Universitäten relevanten Spannungsverhältnis von Zentralität und Dezentralität. Die gehaltenen Vorträge werden in diesem Band dokumentiert.
Homenaje a Esther Chávez Cano
Authors: Villarreal Jiménez Rodrigo
Published: August 2023

Composición original para ensamble mixto de cámara en honor a la activista social mexicana.
Mediaciones tecnológicas del deseo homosexual: un análisis de la exposición “De Ansia y Pudor”
Authors: Radrigán Valeria
Published: August 2023

Introducción: El artículo presenta un análisis de la exposición “De Ansia y Pudor: variaciones sobre cierta construcción del deseo” (2023) de los artistas chilenos Raúl Miranda, Mique Marchant e Ignacio Henríquez. Objetivo: El análisis busca demostrar que las mediaciones tecnológicas, específicamente aquellas que implican las transformaciones de la web 3.0, inciden directamente en la configuración de la sexualidad queer, aspecto que tiene un correlato artístico directo en la exposición. Métodos: Para esto, el texto emplea una metodología cualitativa de enfoque interpretativo, efectuando una descripción contextual y formal de las obras y luego realizando un análisis de tres ejes: las corporalidades, las performatividades del afecto y la sexualidad y la autenticidad. Conclusiones: Finalmente, se plantea que, más que proponer una “subversión” a las codificaciones del deseo, la expresión artística genera aquí una toma de conciencia crítica y sensible del uso de las tecnologías y su incidencia en los afectos y el placer.
Microstructural evolution of 6061 aluminium alloy subjected to static and dynamic compression at low temperature
Authors: Kopec Mateusz , Gorniewicz Dominika , Jóźwiak Stanisław , Janiszewski Jacek , Kowalewski Zbigniew L.
Published: August 2023

In this research, an effect of low temperature on the mechanical properties and microstructure of 6061-T6 aluminium alloy (AA6061-T6) subjected to static and dynamic loading was investigated systematically. The specimens were subjected to compression at the temperature of − 80°C in a range of strain rates from 0.001 to 0.1 1/s under static conditions, and from 1250 to 3400 1/s under dynamic conditions to compare their mechanical responses. The deformation mechanisms were discussed based on EBSD analysis. It was found, that under both testing conditions, dynamic recovery was the dominant mechanism responsible for material deformation.

Graphical abstract
Grey Herons Ardea cinerea hunting and eating Little Swifts Apus affinis
Authors: Piñeiro Xurxo
Published: August 2023

This note reports on Grey Herons' (Ardea cinerea) predation on Little Swifts (Apus affinis) at Bloemhof Dam Nature Reserve, North-West Province.
Exploring the resonance between how mentor teachers experienced being mentored and how they mentor pre-service teachers during teaching practice
Authors: Kasapoglu Koray , Aydogdu Bulent , Uyanik Aktulun Ozgun
Published: August 2023

With the study reported on here we aimed to explore and compare the experiences of pre-service teachers with their mentor teachers and of mentor teachers with their own mentor teachers when they were pre-service teachers. The design of this qualitative research was narrative inquiry. The study group consisted of senior pre-service pre-school teachers taking the Teaching Practice I course (n = 8) in the Faculty of Education at a state university and their mentor teachers (n = 4) teaching in public kindergartens. Qualitative data was collected through individual narrative interviews with pre-service teachers and their mentor teachers. The data was subjected to content analysis using inductive coding. Three themes emerged from the content analysis: (1) mentoring experiences of pre-service teachers and their mentor teachers, (2) mentoring memories of pre-service teachers and their mentor teachers, and (3) wishes of pre-service teachers and of their mentor teachers about mentoring. The most striking finding of this research was that the memories and wishes of pre-service teachers and their mentor teachers about mentoring were similar. The findings of this research are anticipated to bring about different perspectives and contribute to the content and effectiveness of teaching practice courses.
“What if we give them too much voice?”: Teachers’ perceptions of the child’s right to participation
Authors: Munongi Lucia
Published: August 2023

Article 12 (1) of the United Nations Convention on the Rights of the Child sets out the right of children who are capable of forming their own views to freely express them in matters that affect them. Such views should be considered in schools when making decisions, paying attention to the child’s age and maturity. In this study we explored teachers’ understanding and perceptions of the implementation of the child’s right to participation in matters that concern them in the school context. Using a qualitative research approach, data were obtained from 12 purposively selected high school teachers from selected schools in the Johannesburg South district through semi-structured individual interviews. The findings indicate that while understanding of this right was limited among teachers, there was a high preference to accord children this right. Opportunities to participate were mainly viewed as very limited and only in minor issues at school. Several challenges to promote this right were highlighted by teachers and are discussed in this article. Recommendations such as educating teachers about children’s rights to participation and creating opportunities for them to participate in decision-making in matters that concern them are made.