bluuebunny/crossref_metadata_2025 huggingface dataset:
The Lexicon on Natural Knowledge of Umpasa in Batak Toba
Authors: Sitorus Nurhayati , Lubis Tasnim
Published: March 2024

Umpasa is a kind of rhyme used by the Batak Toba tribe in traditional events. Every umpasa conveyed undoubtedly has meaning, and it becomes a guideline for the Batak Toba. This study aims to find the scientific lexicon contained in umpasa, and the meaning of the umpasa. The data is taken from Jambar Hata Dongan Tu Ulaon Adat. Data collection is done through observation and note-taking techniques. After the data is collected, the data is analyzed using Miles and Huberman's analysis, which consists of three stages: the data reduction stage, the data presentation stage, and the data conclusion/verification stage. The result of this study was the lexicon found in umpasa Batak Toba consists of natural knowledge of flora and fauna. Furthermore, the umpasa in Batak Toba functions as a prayer or hope. So, in the example, the Batak Toba characterizes human traits or characteristics from parts of flora and fauna.
Implementation of Human Capital Management in the Sharia Economist Training (SET) Universitas Sumatera Utara
Authors: Adelia Putri , Fathin Najla Hanan , Simanjorang Feronica
Published: March 2024

This research aims to evaluate and describe the implementation of human capital management through the Sharia Economist Training (SET) event to create human capital management in organizations so that they have high motivation in organizational activities. The focus of the research is on human capital management in the form of Individual Capability, Individual Motivation, Leadership, Organizational Climate and Workgroup Effectiveness. This research is research that uses a qualitative paradigm with descriptive qualitative methods. Data was collected through interviews and participant observations carried out by researchers when holding the SET event. Data was analyzed using SWOT analysis to determine the implementation of human capital management at an event. The research results show that the implementation of human capital management in the SET event can improve skills and performance for growth and development in organizations. USU's SET event has fulfilled several components of human capital management. There are also shortcomings in the publication and documentation division and the Daily Management Body (BPH) division which will later be re-evaluated for the next event. It can be concluded that implementing human capital management in an event is very important for the success and smooth running of the event.
МАС-МЕДІА УКРАЇНИ В КОНТЕКСТІ ПОЛІТИЧНИХ ТРАНСФОРМАЦІЙ СУСПІЛЬСТВА
Authors: Матвієнків Світлана , Кирничний Себастьян
Published: March 2024

У статті розглядається роль мас-медіа в Україні в контексті політичних трансформацій суспільства. Досліджується вплив засобів масової інформації на політичний ландшафт країни у період змін, що відбуваються в українському суспільстві. Стаття розглядає важливі аспекти взаємодії між мас-медіа та політичними процесами, звертаючи увагу на роль ЗМІ у формуванні громадянської свідомості, ставлення суспільства до політичних подій і вплив на формування громадянської позиції. Аналізується динаміка змін у мас-медіа просторі України під час переходу до нових політичних реалій, звертається увага на трансформації в роботі ЗМІ та їхню роль у сучасному політичному діалозі.
FENOLOGÍA Y FISIOLOGÍA DE ILAMA (Annona diversifolia Saf.)
Authors: Ruiz-Posadas L.M.
Published: March 2024

Considerando el cultivo de Ilama (Annona diversifolia Saf.) como alternativa sustentable de la fruticultura en trópico seco, se realizó su caracterización fenológica, anatómica in situ y una evaluación de dormancia en condiciones controladas. La Ilama es una especie semi-caducifolia de ciclo fenológico anual discontinuo con una etapa de crecimiento activo y otra de dormancia. El ciclo inicia en marzo-abril con la aparición de brotes reproductivos y vegetativos, la apertura floral tiene lugar en marzo-mayo, fructifica por cinco meses (mayo-septiembre); el crecimiento de ramas, brotes y hojas inicia en primavera y termina en verano. La temperatura es el factor preponderante en la defoliación, aparentemente la sequía solo ejerce un efecto coadyuvante al acelerar la senescencia de la hoja; y presenta características morfológicas y fisiológicas semejantes a especies adaptadas a vivir en hábitats con alta irradiación solar y limitaciones de humedad.
Chilean Identity Performativity in Carmen Aguirreâ€™s Chile Con Carne and The Refugee Hotel: Narrative Evidence of the Shortcomings of Canadaâ€™s Multiculturalism Discourse
Authors: Saldanha Leanne C.
Published: March 2024

Theatre, especially the alternative theatres of immigrant communities, can ask its audience to question social inequities and to seek socio-political change. In my MRP, I use Butlerâ€™s theory of performativity and Brechtian distanciation to analyze nuanced Chilean exilic identity depictions in Carmen Aguirreâ€™s plays: Chile con Carne and The Refugee Hotel. I find that Aguirreâ€™s politically engaged theatre functions as a visceral and compelling counter-narrative that challenges the dominant discourse of Canadian multiculturalism inclusivity. Ultimately, identity

performativity, coupled with Brechtian techniques, allows Canadian audiences to understand the nuanced multiplicity and hybridity of Chilean-Canadian lived experiences as fundamentally Canadian narratives that belong, on their own terms, in a pluralistic Canadian society.

Keywords: Chilean; Exile; Performativity; Identity; Intersectionality; Theatre; Multiculturalism

Discourse.
me-dÃ©rive: toronto: Remediating the [AR]chival Impulse
Authors: Morais Ana Rita
Published: March 2024

This dissertation is an innovative exploration of the intersections between participatory archiving and augmented reality (AR), rooted in the necessity to engage more fully with Torontoâ€™s diverse and historical cultural heritage. Foregrounded as research-creation, this work describes, theorizes, and disseminates an AR counter-archiveâ€” me-deÌ rive: toronto. Mobilizing power away from institutional archives and into the hands of the public, me-deÌ rive: toronto uses the power of locative media in order to provide records of Torontoâ€™s diverse past and present in-situ. A portmanteau of the word â€˜mediationâ€™ and the Situationistâ€™s notion of the deÌ rive, the app produces a new paradigm to the archiveâ€” one that is simultaneously participatory and techno-informed. With every found photograph and submission alike the project multiples both in volume and vigor to combat the archival injustices that fail to narrativize Canadian immigrant identities.Â 

This counter-archive reclaims space through a participatory visual account of history, allowing for a different kind of knowledgeâ€”one that is techno-embodiedâ€”to emerge and be embraced. As the scope of the records and overall scale of the project amplifies, it engages a layer of complementary principlesâ€” the accrual of diverse narratives, the opposition of pre-prescribed history by governing institutions, and the dynamism to employ technology to engage critically with heritage records beyond the confinements of exclusive cultural spaces.Â 

Through historical research, precedent scanning, insights into cultural production, participatory and mobile app observation and research-creation projects, counter-archival projects demand that institutions become more inclusive, not only in collection practices, but in dissemination and access practices as well. My research addresses the gaps and omissions that exist in our institutional archives, while making explicit what is needed to make a more holistic, comprehensive archive of Torontoâ€™s diverse narratives.Â 
Itâ€™s Alive! Using Linked Open Data to promote discovery within artist-run centre collections
Authors: Gagnon Shannon
Published: March 2024

The Western Front Societyâ€™s Reverie: Noise City (2005) is a website platform originally built to present live performance art for their annual â€œArtâ€™s Birthdayâ€ event. The Reverie website envisions a â€œvirtual cityâ€ where online audiences witness these performances and today serves as an archive for the web-streamed events. Despite its innovative nature, the websiteâ€™s content remains largely undiscoverable and hard to access due to the limited terminology exposing the website to search engine queries, the lack of a sitemap in HTML for the website sub-links, and the absence of structured machine-readable data. Using the Reverie website as case study, I argue for the use of Linked Open Data technologies within artist-run organizations hoping to improve discoverability of their multimedia assets. I create a machine-readable document to advance the Reverie websiteâ€™s Search Engine Optimization (SEO) and provide an outline of my methodology to be used by like-minded archivists and artists.
Assessing the Functional Dynamics of Ontario’s Electric Vehicle Technology Innovation System Under the Current Niche-regime-landscape Structure
Authors: Al Sawajneh Zoulina
Published: March 2024

Reducing transportation emissions is one of Ontario’s goals to tackle climate change. This thesis research analyzes the transition to electric vehicles (EVs) by using the technology innovation system (TIS) and the multi-level perspective (MLP) approaches to assess the functional dynamics of Ontario’s EV TIS under the current niche-regime-landscape structure. Although Ontario has outstanding domestic auto industry capability, the diffusion of EVs is relatively low. However, the analysis shows that Ontario might be on track to achieve the goal of light-duty vehicle emission reduction by 2030 due to the potential transition to the mass EV market. Entrepreneurial initiatives and the exogenic-driven legitimacy functions are recognized as the main motors to reinforce the functional dynamics and development of Ontario’s EV TIS. However, the lack of robust supply and demand-focused policies to open and lead the market to entrepreneurial enterprises and to innovate the status quo of the established auto industry regime in a timely manner may inhibit the formation of competitive EV TIS in Ontario.
On-demand Ride-hailing as Publicly Subsidized Mobility: An Empirical Case Study of Innisfil Transit
Authors: Benaroya Anne
Published: March 2024

This empirical case study examines Innisfil Transit, a partnership between Uber and the low-density rural Town of Innisfil, Ontario, which subsidizes ride-hailing trips as an alternative to fixed-route transit. The Innisfil Transit program underwent multiple policy changes, providing an opportunity to learn about the links between program design and use. Using descriptive statistics, cross sectional, and panel models, this study explores the predictors of ride-hailing ridership and growth between 2016 and 2020 as a function of neighborhood-level and policy-related variables. Results indicate that the Innisfil Transit program initially eased Uber ridership (implying substitution), however this impact was not long lasting. Evidence indicates that program design impacts both overall ridership and growth over time, and that urbanized areas and young adults are associated with increased ride hailing use. The results of this paper can be used by municipalities considering the implementation of subsidized ride-hailing programs in determining program goals and design.
How Well We Know Wellness: Closing the Gap on Wellness Program Research in the Workplace Through Mixed-methods Topic Modelling
Authors: Kavaratzis Steven
Published: March 2024

This research brings together a systematic literature review, topic modeling, and qualitative analysis in a novel, mixed method approach to synthesize research on workplace wellness interventions and offer directions for future research. First, we conducted a systematic literature review to create a corpus of 5,674 research publications on wellness intervention research. Next, topic modeling, a quantitative machine learning technique that identifies key topics, was deployed to extract trends within the corpus. Finally, abstracts were qualitatively coded according to a framework that examined: 1) journal outlets and disciplines publishing workplace wellness intervention research; 2) different types of wellness interventions that are studied in workplaces; 3) dependent variables measured as outcomes of wellness interventions, and any reported mechanisms or theories of change linking the intervention to the outcomes; 4) methodologies utilized by researchers and their corresponding rigor; and 5) context the research takes place within. Interestingly, despite growing recognition that wellness is multi-dimensional, ‘wellness’ is increasingly operationalized using primarily psychological outcomes. Other trends depicted a lack of consistency in research design, program theory, and results making it difficult to specify how or why a program is beneficial for a specific population and setting, and the extent to which results were reliable.
Pengaruh Penggunaan Media Blog Terhadap Minat Belajar Siswa pada Keterampilan Menulis Pengalaman Pribadi
Authors: Rida Andi , Bahri Aliem , Paida Andi
Published: March 2024

The purpose of this research is to determine the use of blog media on learning interest in writing skills, and personal experiences of class V students at SDN 179 Tanah Beru, Bulukumba Regency, in terms of the use of student interest response questionnaires. The type of research used is pre-experimental research. The research design used is a one-shot case study, namely experimental research carried out by demonstrating the strength of measurement and scientific value of a research design. The experimental subjects in this research were 19 students as a trial class to apply the use of blog media. The data collection technique used is a questionnaire technique of student learning interests or student responses. The research results show that from the results of the data analysis of the student interest in learning questionnaire, the ideal score is 92.89%, which is in the very good category. So, it can be concluded that the influence of using blog media on interest in learning the personal experience writing skills of class V students at SDN 179 Tanah Beru, Bulukumba Regency is in the very good category.
Perbandingan Tingkat Stres Mahasiswa Tahap Akademik FK UMI Angkatan 2017, 2018 dan 2019
Authors: Dedy Kurniawan  , Mokhtar Shulhana , Rasfayanah  , Yani Sodiqah  , Arifin Arina Farhiyyah , Nur Isra  , Uyuni
Published: March 2024

Stres adalah kondisi yang disebabkan oleh interaksi antara individu dengan lingkungan yang menimbulkan persepsi jarak antara tuntutan-tuntutan yang berasal dari situasi yang bersumber pada sistem biologis, psikologis dan sosial dari seseorang. Mahasiswa yang mengalami stres membutuhkan perhatian serius karena dapat membawa dampak yang kurang baik terhadap proses pembelajaran dan prestasi mahasiswa. Berbagai penelitian telah mendokumentasikan stres di kalangan mahasiswa kedokteran dan menunjukkan adanya stres yang sangat tinggi apabila dibandingkan dengan program studi lain di sektor non-medis. Tujuan dari penelitian ini yaitu untuk mengetahui perbandingan tingkat stres mahasiswa tahap akademik Fakultas Kedokteran UMI angkatan 2017, 2018 dan 2019.
Karakteristik Kanker Panyudara
Authors: Andi Herawati  , Syamsu Rijal  , Arsal Andi Sitti Fahirah , Reeny Purnamasari  , Abdi Dian Amelia , Syarifuddin Wahid
Published: March 2024

Kanker payudara menempati urutan pertama jumlah kasus kanker sekaligus menjadi penyebab kematian terbesar akibat kanker di dunia setiap tahunnya. Adapun faktor risiko yang erat kaitannya dengan peningkatan insiden kanker payudara yaitu jenis kelamin perempuan, usia >50 tahun, riwayat keluarga dan genetik, riwayat penyakit payudara, riwayat menstruasi/menarche dini (<12 tahun) atau menopause lambat (>55 tahun), riwayat reproduksi (tidak memiliki anak dan tidak menyusui), hormonal, obesitas, konsumsi alkohol, riwayat radiasi dinding dada, serta faktor lingkungan. Tujuan penelitian untuk mengetahui karakteristik pada penderita kanker payudara. Metode penelitian ini menggunakan Literature Review dengan desain penelitian narrative review. Hasil Dari 23 literatur ditemukan bahwa karakteristik pada penderita kanker payudara didominasi berusia ≥40 tahun dengan range usia 40-55 tahun. Risiko kanker payudara meningkat 10 kali lebih besar terhadap keluarga yang mempunyai ibu, saudara perempuan atau putri yang menderita kanker payudara. Riwayat reproduksi seperti usia menarke, menopause, riwayat paritas dan menyusi juga dapat meningkatkan risiko terjadi kanker payudara. Riwayat penggunaan kontrasepsi oral dan pil dapat meningkatkan risiko terjadi kanker payudara sampai 4 kali lipat lama (penggunaan ≥5 tahun). Distribusi stadium penyakit penderita kanker saat terdiagnosis stadium III B dan IV. Jenis terapi yang paling banyak digunakan pada kanker payudara adalah kemoterapi dan mastektomi. Kesimpulan dari penelitian ini yaitu Usia ≥40 tahun, riwayat keluarga, riwayat penggunaan kontrasepsi hormonal, riwayat reproduksi memiliki pengaruh kejadian kanker payudara. Stadium penyakit penderita kanker saat terdiagnosis adalah stadium III B dan IV Kemoterapi dan mastektomi merupakan terapi yang paling banyak digunakan pada kanker payudara.
Polityka pieniężna NBP a ceny produktów rolnych w czasie COVID-19
Authors: Jędruchniewicz Andrzej , Wielechowski Michał
Published: March 2024

Celem opracowania jest ocena oddziaływania polityki monetarnej prowadzonej przez Narodowy Bank Polski na dynamikę cen skupu produktów rolnych. W okresie pandemii COVID-19 polityka NBP stała się wyjątkowo łagodna. Bezpośrednią konsekwencją takich działań był dynamiczny wzrost podaży pieniądza. Opóźnionym skutkiem było pojawienie się znaczących procesów inflacyjnych w polskiej gospodarce. Analiza danych rocznych wskazuje, że w latach 2019–2022 wpływ wzrostu podaży pieniądza na wahania cen skupu produktów rolnych był opóźniony o około jeden rok. Natomiast ekonometryczna analiza oparta na przyrostach rocznych publikowanych co miesiąc, po usunięciu trendów, wskazuje, że wpływ wzrostu ilości pieniądza M1 na zmiany cen rolnych był najsilniejszy przy opóźnieniu 18 miesięcy. Zmiana agregatu M1 wyjaśniała zmiany cen skupu w 40%. Oddziaływanie NBP na ceny rolne było bezpośrednie, jak i pośrednie poprzez wpływ na wzrost kosztów produkcji w polskim rolnictwie.
From Fluids to Pharmaceuticals: How Computational Fluid Dynamics (CFD) Transforms Drug Design
Authors: Singh Vishal Kumar
Published: March 2024

Computational Fluid Dynamics (CFD) is a powerful tool that helps scientists and engineers understand how fluids behave and move, whether in the air, liquids, or biopharmaceutical manufacturing processes. This technology, which uses computer simulations to replicate real-world scenarios, plays a critical role in various industries, including medicine and drug development. By creating virtual experiments on computers, CFD allows researchers to gain insights into the interaction of biological components for drug production at different scales, from small laboratory experiments to large-scale manufacturing processes and fast-track process optimisation. The strategy and implementation of CFD for a bioreactor system has been explained in this article.
Can Rights of Nature Contribute to Enhanced Environmental Protection in Ireland?
Authors: Suarez Julian
Published: March 2024

Several sectors of Irish society have put forward rights of nature as a way to further enhance environmental protection in the country and help curb environmental degradation. In light of rights of nature developments in other jurisdictions, this piece presents rights of nature in their social, economic, and legal context, and summarises their reception by legal scholars. This portrayal will provide a basis for analysing the two main Irish rights of nature legal propositions and assess, albeit in preliminary fashion, whether these initiatives – if enacted – would further enhance environmental protection in Ireland.
Entscheidungsfindung und Entscheidungshilfen am Lebensanfang
Authors: Körtner H J , Kopetzki Christian , Kletecka-Pulker Maria , Müller Sigrid
Published: March 2024

Die Zukunft von Schwangerschaft und Geburt im Zeitalter ihrer Medikalisierung Will man die geschichtlichen Veränderungen, denen Schwangerschaft und Geburt vom 17. bis 21. Jahrhundert unterworfen sind, mit einem Schlagwort bezeichnen, drängt sich der Begriff der Medikalisierung auf. Die fortschreitende Medikalisierung und Technisierung bestimmen auch die Zukunft von Schwangerschaft und Geburt. Entscheidungsfindung und Entscheidungshilfen am Lebensanfang sind nicht nur eine individualethische, sondern auch sozialethische Frage, die in einen größeren historischen Kontext eingebettet ist. Um die heutigen Problemstellungen und Konfliktlagen um Schwangerschaft und Geburt zu verstehen, genügt nicht ein Blick auf den gegenwärtigen Stand von Geburtshilfe und Medizin und die in ihnen herrschende Entwicklungsdynamik. Es sind vielmehr auch die soziokulturellen Veränderungen zu reflektieren, die das individuelle Geschehen von Schwangerschaft und Geburt und seinen systemischen Kontext im Gesundheitswesen beeinflussen. Der vorliegende interdisziplinäre Band möchte nicht nur praktische Hilfestellungen leisten, sondern auch zu einem vertieften Verständnis der historischen Umbrüche rund um Schwangerschaft und Geburt beitragen. Die Beiträge befassen sich mit medizinischen, rechtlichen, ethischen und kulturwissenschaftlichen Fragen. Ein besonderer Schwerpunkt liegt auf Stand und Entwicklung von Pränatal- und Präimplantationsdiagnostik. Dazu kommt auch die Klinikseelsorge zu Wort. Auch der Kaiserschnitt als Geburtsmethode des 21. Jahrhunderts ist ein Thema. Außerdem dokumentiert der Band eine Leitlinie zur Erstversorgung von Frühgeborenen an der Grenze der Lebensfähigkeit.
Tolerância ao exercício na tetralogia de Fallot pós-reparo: uma revisão sistemática com meta-análise
Authors: Sacramento Marvyn de Santana do , Cedraz Thais de Figueiredo , Moura Manuela da Silva , Barbosa Ramon Martins , Jesus Tailma Costa de , Santos Ana Glice Aragão , Souza Pedro Elias Santos , Petto Jefferson
Published: March 2024

Introdução: A tetralogia de Fallot (TOF) é a cardiopatia congênita cianótica mais prevalente, representando cerca de 10 a 15% das cardiopatias congênitas. O tratamento da TOF é feito através do reparo cirúrgico de anomalias anatômicas cardíacas. Porém, mesmo após correção completa no TOF, há diferença na capacidade cardiorrespiratória entre pessoas com TOF corrigida e seus pares saudáveis. Objetivo: Comparar a capacidade cardiorrespiratória de pessoas com e sem TOF por meio da literatura especializada. Metodologia: Trata-se de uma revisão sistemática com meta-análise registrada no Prospero sob o número: CRD42020205264. As buscas foram realizadas nas bases de dados Medline via PubMed, PEDro e SciELO por meio do cruzamento dos Descritores em Ciências da Saúde (DeCS) e Medical Subject Headings (Mesh): ((Fallot Tetralogy) AND (exercise)), sem restrições temporais ou linguísticas. Resultados: Sete estudos foram selecionados para a síntese qualitativa, 3 foram incluídos para a metanálise onde houve atenuação do consumo máximo de oxigênio (-6,56 [IC95%: -11,24; -1,89] e da frequência cardíaca máxima (-21,47 [IC95 %: -40,09; -2,85]) de pessoas com TOF corrigida em comparação com seus pares saudáveis. Conclusão: Indivíduos com TOF, mesmo após reparo cirúrgico, apresentam menor tolerância durante testes de exercício específicos.
O candeeiro: instrumento de comunicação popular no fortalecimento da agricultura familiar de base agroecológica no Sertão do Pajeú, Semiárido Brasileiro.
Authors: Gonçalves Rosy Kátia Souza , Freitas Helder Ribeiro , Nascimento Júnior Braz José do
Published: March 2024

Este trabalho objetiva analisar como o boletim “O Candeeiro”, instrumento de comunicação da Articulação no Semiárido Brasileiro (ASA Brasil), fortalece a agricultura familiar e a agroecologia noSertão do Pajeú. Trata-se de uma pesquisa bibliográfica e documental na qual se fez o levantamento e análise dos temas e experiências exitosas sistematizadas e publicadas no “site” da ASA Brasil entre os anos 2012 e 2020. Também foi realizada uma entrevista com 17 pessoas que leem e utilizam as informações contidas no periódico analisado. Observou-se que essas práticas e iniciativas envolvem dimensões importantes para o fortalecimento da agricultura familiar no semiárido, com destaque para o acesso à terra e à água, conservação de sementes crioulas e o protagonismo da mulher que demandam ações de políticas públicas de convivência com o semiárido. Conclui-se que “O Candeeiro” promove a troca de saberes e experiências exitosas no Sertão do Pajeú inspirando mudanças
Avaliação das TICs na realização da educação popular em comunidade de reassentados
Authors: Leite Daniel de Carvalho , Santos Delfran Batista dos , Souza Heron Ferreira , Souza Antonio José de , Azevedo Delka de Oliveira
Published: March 2024

Visando à reinserção socioprodutiva de famílias reassentadas, foi realizada uma capacitação, presencial, sobre a produção de hortaliças agroecológicas na Vila Produtiva Rural Uri (VPR Uri). No entanto, com a chegada abrupta do novo Coronavírus, o diálogo com as famílias e o acompanhamento ao desenvolvimento da horta teve que ser realizado de forma remota. Diante disso, este trabalho tem por objetivo analisar se o uso das TICs contribui na prática da Educação Popular voltada para a produção agroecológica de hortaliças na VPR Uri. Por meio de um grupo de WhatsApp, constatou-se que as famílias estavam com dificuldades para o cultivo das plantas devido ao ataque de insetos e de doenças. Para tentar resolver esse problema, foram enviados vídeos orientando como preparar biofertilizantes e defensivos naturais. Houve boa interação por parte das famílias, contudo não foi possível perceber se o conteúdo de todos os vídeos foi realmente compreendido e nem as causas do ataque dos insetos e das doenças nas plantas.
Efficacy of Oral Prednisolone in the Management of Idiopathic Granulomatous Mastitis
Authors: Tazdina Hoque Khan  , Shahidul Huq  , S M Minhajul Hasan Chowdhury  , Tahira Benzir  , Abdullah Al Maruf  , Faisal Mostafa  , Syed Aminul Haque
Published: March 2024

Background: Idiopathic granulomatous mastitis (IGM) is a benign inflammatory lesion of the mammary gland. Globally it possesses a major diagnostic and therapeutic problem. To date, there is no universally agreed treatment for this condition. Many treatment modalities have been attempted from conservative therapy to mastectomy but none of them has shown satisfactory results. Recent studies have shown promising results of corticosteroids on idiopathic granulomatous mastitis, so steroid therapy can be an effective treatment for idiopathic granulomatous mastitis. The goal of the study is to provide a therapeutic strategy in the future for idiopathic granulomatous mastitis. Methods: Our study included all patients with idiopathic granulomatous mastitis confirmed histologically by core needle/incisional biopsy at the general surgery unit of Chittagong Medical College Hospital and the private hospitals in the Chittagong Metropolitan City for a period of one year from October 2016 to September 2017. A total of seventy patients were included in the study provided they fulfilled predetermined criteria. All of them were included in this study by purposive sampling.  After diagnosis oral prednisolone (1mg/kg/day) was given and the cases were observed by personal interview and through telephone interview. The patients were on follow-up for 06 months. Age, size of the breast lump, breast pain, nipple discharge, and skin changes were recorded in all cases. Results were analyzed using mean, percentage, and proportion as appropriate. Results: The mean age was 26.35±13.5 years ranging from 19 to 40 years. Out of 70 patients, Core cut biopsy was done in 55 patients (78.58%), and incisional biopsy with abscess drainage was performed in 15 patients (21.42%). 59 patients (84.28%) had complete recovery after a single cycle of steroid treatment, remaining 11 patients (15.72%) had recurrence, among them 6 patients were cured after 2nd cycle of steroids but unfortunately, 5 patients did not respond. Though complications were found in 50 patients, all of them made good progress in the short term. Conclusion: We recommend steroid therapy as the first-line treatment in our study. However, prospective, randomized clinical trials are needed to determine the treatment algorithm.
Mediscope 2024;11(1): 22-26
Characteristics of Patients with Hypertension Admitted for COVID-19 Treatment in Khulna: Single-Centre Cross-Sectional Study
Authors: Muhammad Ashraful Kabir  , Biplab Kumar Roy  , Baishakhi Islam  , Syed Didarul Haque
Published: March 2024

Background: The outbreak of coronavirus disease 2019 (COVID-19) has become a large threat to global health due to its high contagious nature and varied mortality. Arterial hypertension represents one of the most common comorbidities in patients with COVID-19. Close connections between inflammation and blood pressure (BP) have been described, and inflammation plays a key role in the outcome for patients with COVID-19.
Objective: This study aims to investigate the clinical characteristics of patients with hypertension admitted for COVID-19 treatment in Gazi Medical College Hospital (GMCH), Khulna, Bangladesh.
Methods: This was a cross-sectional type of observational study on patients with hypertension who were diagnosed with COVID-19 based on laboratory and/or radiological findings and admitted to Gazi Medical College Hospital, Khulna, Bangladesh, from July 1 to July 31, 2021. In that timeframe, overall, 215 patients with COVID-19 were admitted. Among them, 37 patients having hypertension fulfilled the inclusion criteria for the study. Demographic, clinical, laboratory and radiological data of those 37 patients were recorded and analyzed.
Results: Among 37 study subjects, 54.1% were female. The mean age of the patients was 59.6±13.9 years. Among the study subjects, diabetes (56.8%) was the most common comorbidity. Regarding laboratory parameters, the mean Hb of the patients was 11.4±1.9 g/dl. In addition, the mean random blood sugar (RBS) level was 11.6±2.9 mmol/l. Neutrophilia and lymphocytopenia were observed in 86.5% and 83.8% cases, respectively. The mean D-dimer (2.4 mg/l) and CRP (72.5 mg/l) levels were well above their normal limits. In high resolution CT scan of the chest (HRCT chest), bilateral lung involvement was present in 89.2% cases. Ground-glass appearance was the most frequent (91.9%) radiologic pattern. Among antihypertensive drugs, losartan potassium was the most frequently used category (29.7%). Total 7 (18.9%) patients were severely affected with COVID-19 and admitted to the ICU, requiring mechanical ventilation. During our study, 2 patients (5.4%) died either due to multiple organ dysfunction syndrome or cardio-respiratory failure.
Conclusion: The study provides key information to better understand the clinical characteristics of patients with hypertension admitted for COVID-19 treatment, which may help physicians to identify the factors associated with adverse outcomes in this disease.
Mediscope 2024;11(1): 34-40
The case of successful surgical treatment of a female patient with a break in a large cerebral aneurysm
Authors:   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai, Kosmachev M.V. , Chepelianskaya M.V. ,   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Unzhakov V.V. ,   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai, Doloka A.S. ,   Max Clinic, The Far Eastern Center for Innovative Diagnostics and Endoscopic Surgery, Khabarovsk, Russia, Kovtun M.A. ,   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Polyakov A.G. ,   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Bashkirov S.G. ,   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Shevchuk M.V. ,   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry
Published: March 2024

The article presents a clinical case of successful treatment of the female patient with the internal carotid artery (VSA) exploded with a large aneurysm. The relevance of the problem is due to the complexity of the surgical treatment of giant cerebral aneurysm due to the need to have special surgical clips and intraoperative visualization (ultrasound, videoangiography), as well as a high risk of thrombomebole and thromboembolism.
Shwachman–Diamond syndrome. Not rare symptoms in a rare patient
Authors:   Postgraduate Institute for Public Health Workers of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Filippova V.V. , Yershova M.I. ,   Children's City Out-patient Clinic No. 17 of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Solopenko E.L. ,   Children's City Out-patient Clinic No. 17 of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia, Voroshchuk A.A. ,   Children's City Out-patient Clinic No. 17 of the Ministry of Health of the Khabarovsk Krai, Khabarovsk, Russia
Published: March 2024

The article presents modern information about the congenital disease of the pancreas - Shwachman-Diamond syndrome. Own observation and results of the examination of the child with the specified syndrome are given.
Konya Arkeoloji Müzesi’nden Bir Grup Metal Eser
Authors: ÖZCAN Ali
Published: March 2024

Bu makale ile Konya Arkeoloji Müzesi koleksiyonunda bulunan 3 kolcuklu balta, 9 yassı balta/keski ve 2 keskiden oluşan toplam 15 adet maden eser yayınlanmaktadır. Eserler üç farklı gruptan oluşmaktadır. Kolcuklu baltalar, gövdelerinin her iki kısmında kolcuk adlı çıkıntıları olan balta biçimidir. Yassı gövdeli, dar ense kısmından teber kısmına doğru genişleyen eserler yassı balta/keski olarak adlandırılmaktadır. Uzun/kısa boyutlu, dörtgen/kare kesitli gövdeli, ağızları dövülerek düzleştirilmiş eserler keski grubunu oluşturmaktadır. Eserler, 2010 ve 2015 yıllarında İbrahim Bağcı tarafından müzeye getirilmiştir. Envanter kayıtlarında eserlerin buluntu yerleri hakkında belirgin bir bilgi mevcut değildir. Kazı buluntusu olarak ele geçmiş ve yayını yapılmış benzer balta tipleri dikkate alınarak analoji yöntemi ile eserlerin tarihlendirilmeleri yapılmıştır. Çalışmamızda eserlerin ait oldukları balta ve keski tipleri ile kullanım alanları hakkında bilgiler verilmiştir. Yayımladığımız eserlerin durumu ve benzerlerinin işlevlerini dikkate alarak özel amaçlar (ritüeller, törenler vs.), taş, maden ve ahşap işlerinde kullanılmış aletler oldukları söylenebilir. Yayını gerçekleştirilen maden eserler, Orta Tunç Çağı ve Geç Tunç Çağı’na tarihlendirilmiştir. Çalışma konusunu oluşturan kolcuklu, yassı balta/keski ve keskilerin Orta ve Kuzey Anadolu’da ele geçen eserler ile benzer özelliklere sahip olduğu görülmüştür. 1, 5, 13 ve 14 katalog numaralı eserlerin tek parça kalıpta üretilmesi yerel işçilik özelliği olarak değerlendirilebilir. Bu çalışma ile 15 parça eseri inceleyip yayınını gerçekleştirerek, maden eserler konusunda bilimsel literatüre katkı sağlamak amaçlanmıştır.
Perancangan Brand Identity UMKM Cerys Bites di Kota Malang dengan Metode Moser untuk Membangun Brand Awareness
Authors: Santoso Elsa Febritha , Nirwana Aditya , Prasetya Bintang Pramudya Putra
Published: March 2024

UMKM memiliki peran yang penting dalam perekonomian karena kemampuannya untuk menyerap tenaga kerja secara merata, terutama pada sektor makanan dan minuman. Secara khusus, sektor makanan ringan seperti cookies, wafer, dan biskuit. Peran UMKM tersebut juga dirasakan di Kota Malang yang memiliki banyak brand cookies, salah satunya adalah Cerys Bites. Dalam persaingan antar brand, Cerys Bites masih belum mendapat awareness yang cukup. Untuk itu dirancang brand identity dengan harapan mampu meningkatkan awareness masyarakat. Dalam perancangan ini digunakan metode perancangan brand model Moser dengan metode penelitian kualitatif. Berdasarkan analisis dan sintesis konsep ditemukan bahwa Cerys Bites memiliki nilai inti, pesan inti, dan kepribadian merek yang menjadi konsep visual dalam perancangan brand identity Cerys Bites. Melalui perancangan ini didapatkan hasil berupa kenaikan interest pada Instagram Cerys Bites yang ditinjau dari kenaikan activites Instagram berupa likes, comment, share, dan save. Hasil dari uji efektifitas mengatakan terdapat kenaikan interest Instagram Cerys Bites yang membuktikan brand identity yang tepat dan konsisten dapat membangun awareness masyarakat.
EVALUATION OF THE IMPACT OF DIFFERENT SUPERDISINTEGRANTS ON THE IN VITRO CHARACTERIZATION PARAMETERS OF ORALLY DISINTEGRATING TABLETS CONTAINING KETOPROFEN
Authors: ÇOMOĞLU Tansel
Published: March 2024

Objective: Orally Disintegrating Tablets (ODTs) have revolutionized pharmaceutical drug delivery, offering a patient-friendly alternative for those struggling with conventional tablet swallowing. This study delves into the impact of superdisintegrants (crospovidone, sodium starch glycolate, and croscarmellose sodium) on the in vitro characterization of Ketoprofen-containing ODTs. ODTs are designed to rapidly disintegrate in the oral cavity without water, enhancing patient compliance, ensuring faster therapeutic onset, and providing convenience.
Material and Method: The micromeritic properties of pre-compression Ketoprofen ODT blends were assessed for bulk density, tapped density, Hausner ratio, and compressibility index. ODTs were formulated using a direct compression method to maintain component uniformity. Comprehensive characterization included weight variation, tablet hardness, friability, wetting time, and in vitro disintegration time assessments. The drug content was determined through UV spectrophotometry of dissolved ODTs, and dissolution studies were conducted in pH 6.8 phosphate buffer using USP apparatus XXIV.
Result and Discussion: Results showed uniform tablet mass and favorable powder mixture flowability, ensuring ODT physical properties. Tablets exhibited excellent mechanical resistance with consistent hardness and low friability loss. All formulations demonstrated high and uniform drug content. Different superdisintegrants influenced wetting, disintegration, and dissolution times. Crospovidone exhibited the fastest wetting time but longer disintegration times, attributed to increased tablet hardness. Dissolution studies revealed that crospovidone-containing ODTs had faster drug release compared to croscarmellose sodium and sodium starch glycolate, aligning with literature findings. The study emphasized the importance of considering both wetting and disintegration times for a comprehensive evaluation of ODT performance. Croscarmellose sodium and sodium starch glycolate hindered drug release, forming gel-like masses impeding dissolution, while crospovidone enhanced drug release in formulated ODTs. In conclusion, the study provides valuable insights for pharmaceutical development and patient-centric drug delivery solutions, showcasing the influence of superdisintegrants on ODT performance and emphasizing the importance of considering various parameters for comprehensive evaluation.
Formulasi Sistem Vesikel Elastik Surfaktan Nonionik Ekstrak Etanol Rimpang Etlingera alba dalam Sediaan Gel
Authors: Indalifiany Astrid , Suryani  , Wahyuni  , Sahidin  , Wa Ode Erna Fitriani
Published: March 2024

Etlingera alba is a plant in Southeast Sulawesi that has antioxidant activity. Natural ingredients such as herbal medicine require a delivery system that facilitates them to reach the site of drug action, especially for transdermal delivery. The elastic vesicle system is a transdermal delivery system that can increase the penetration of active substances at the skin through the act of phospholipids on the skin's lipid bilayer and the deformability of the vesicles. This study aims to formulate and evaluate Etlingera alba rhizome ethanolic extract's elastic vesicle gel to obtain the optimal concentration of Tween 60 as a vesicle former and carbopol as a gel base. Preparation of elastic vesicles of Etlingera alba ethanolic extract using the heat method through variations Tween 60's concentration, namely 5%(F1); 10%(F2); 15%(F3); and 20%(F4). Meanwhile, elastic vesicle gel formulation of the ethanol extract of Etlingera alba rhizome used various concentrations of 0.5% carbopol gel base (FGel 1); 1% (FGel 2); 1.5% (FGel 3); and 2% (FGel 4). The results obtained were the optimum concentration of Tween 60 as a constituent of elastic vesicles of 15% (F4) with spherical morphology using an optical microscope, vesicle size of 10.45 nm, and polydispersity index of 0.280 using a Particle Size Analyzer. In addition, the optimal concentration of carbopol as a base for elastic vesicle gel is a concentration of 0.5% (GGel 1) with white color, distinctive aroma, and thick texture, and has a pH of 6, a viscosity of 2,366 cPs, spread of 6.8 cm, and physically stable through cycling test.
Formulasi dan Karakterisasi Sediaan Spray gel Ekstrak Etanol Buah Pare (Momordica charantia L)
Authors: Akib Nur Illiyyin , Sabarudin  , Sitti Raodah Nurul Jannah  , Desi Nur Sholiha
Published: March 2024

Bitter melon (Momordica charantia L.) fruit has been empirically used as an antibacterial and reported to have activity against acne-causing bacteria. This study aimed to formulate bitter melon ethanol extract in a spray gel preparation and test its activity against Staphylococcus epidermidis as one of the acne-causing bacteria. Pare fruit extract concentrations of 0.5%, 1%, and 2.5% are formulated into spray gel preparations with additional ingredients, Carbopol 940 0.1%, triethanolamine 0.5%, propylene glycol 15%, DMDM Hydantoin 0.6% and aquadest. The characterization of the physical properties of the spray gel preparation included organoleptic, homogeneity, pH, viscosity, and dry time test. The results showed that the spray gel preparation of ethanol extract of Pare fruit had a liquid texture, brownish-yellow colour, and distinctive odour and was homogeneous. The spray gel preparation also meets pH, viscosity and dry time requirements. The antibacterial activity of spray gel preparations resulted in a diameter response of potent and robust inhibition.
Formulasi dan Evaluasi Krim Kombinasi Tawas dan Ekstrak Lidah Buaya (Aloe vera) sebagai Antiperspirant
Authors: Mahmudah Rifa'atul , Hasanah Restu Nur , Aspadiah Vica , A.Sida Nurramadhani , Hikmah Nurull , Akib Nur Illiyyin , Zubaydah Wa Ode Sitti , Primawanty Amilia
Published: March 2024

Bau badan merupakan salah satu masalah yang ada di negara tropis seperti Indonesia. Bau badan disebabkan adanya aktivitas bakteri pada cairan keringat, sehingga untuk mencegah terjadinya bau badan dapat dilakukan dengan mengurangi volume keringat atau melawan bakteri penyebab bau badan. Tujuan penelitian ini adalah untuk memformulasi sediaan krim antiperspirant yang mengandung kombinasi tawas sebagai antiperspirant dan ekstrak lidah buaya (Aloe Vera L.) sebagai pelembab untuk mengurangi terjadinya iritasi kulit. Sediaan krim dipilih karena mudah diaplikasikan dan nyaman digunakan. Ekstrak lidah buaya diperoleh dengan cara ekstraksi infudasi. Krim dibuat dengan mencampur fase air dengan fase minyak lalu diaduk hingga homogen. Evaluasi kestabilan krim dilakukan dengan metode cycling test selama 6 siklus dan diamati perubahan pada sifat organoleptik, homogenitas, nilai pH, dan daya sebar sediaan. Uji antiperspirant dilakukan dengan menghitung jumlah keringat yang keluar pada 10 sukarelawan. Formula sediaan krim yang dihasilkan menunjukkan sifat fisika yang sesuai persyaratan serta stabil secara fisik berdasarkan hasil cycling test. Berdasarkan uji aktivitas antiperspirant terhadap 10 panelis didapati bahwa sediaan krim mampu menggurangi volume keringat hingga 25%. Kesimpulan yang diperoleh bahwa tawas dan Aloe vera dapat diformulasikan menjadi sediaan krim yang stabil dan memiliki aktivitas pengurangan jumlah volume keringat hingga 25%.
EDUKASI PENGGUNAAN ANTIBIOTIK RASIONAL DI DESA PESISIR WAWORAHA KECAMATAN SOROPIA KONAWE SELATAN SULAWESI TENGGARA
Authors: Ihsan Sunandar , Ruslin Ruslin , Henny Kasmawati  , Munasari Solo Dian
Published: March 2024

Penggunaan antibiotik di indikasikan untuk infeksi bakteri, namun dalam praktek penggunaanya di masyarakat masih banyak dijumpai tidak rasional. Hal ini dapat menyebabkan resistensi antibiotik yang terus meningkat. Diperlukan edukasi pada masyarakat untuk meningkatkan penggunaan antibiotik yang bijak dan rasional. Kegiatan ini dilakukan untuk mengedukasi masyarakat pesisir agar menggunakan antibiotik lebih tepat, aman dan efektif. Kegiatan ini dilakukan Desa Waworaha Kecamatan Soropia, Kabupaten Konawe Selatan. Metode yang digunakan adalah ceramah dan tanya jawab. Target sosialisasi adalah masyarakat umum dengan target khusus berupa ibu-ibu PKK, karang taruna dan warga sekitar lokasi sosialisasi yaitu di Balai Desa Waworaha. Selain ceramah juga dibagikan leaflet yang berisi informasi penggunaan antibiotik yang rasional. Pembagian leaflet dilakukan oleh mahasiswa PSPPA FF UHO yang tersebar diantara peserta sosialisasi yang bertujuan untuk pemberian informasi lebih lanjut dari materi edukasi yang diberikan. Hasil kegiatan menunjukan masyarakat antusias dengan materi sosialisasi yang ditandai dengan banyaknya pertanyaan yang diajukan oleh peserta sosialisasi. Pertanyaan tersebut berkaitan dengan apa itu antibiotik, bagaimana cara minum obatnya, apa yang harusnya dihindari kalau minum amntibiotik, bisakah minum antibiotik untuk sakit gigi, demam dan flu serta apakah antibiotik diminum hanya diwaktu sakit saja. Pertanyaan ini menunjukan tingkat pengetahuan warga tentang antibiotik memang masih kurang. Diharapkan dengan informasi yang diberikan baik dari materi sosialisasi, leaflet dan jawaban dari pertanyaan yang diajukan, pemahaman masyarakat Desa Waworaha dapat lebih bijak dan rasional dalam menggunakan antibiotik.

Oleh karena itu peningkatan pemahaman terhadap masyarakat perlu terus dilakukan untuk menjamin peningkatan penggunaan antibiotik yang lebih bijak dan rasional.
PENINGKATAN PEMAHAMAN DAN KEWASPADAAN MASYARAKAT TERHADAP KASUS PENYAKIT MENULAR SEKS DI SMA NEGERI 5 KENDARI
Authors: Wa Ode Sitti Zubaydah  , Irvan Anwar  , Sitti Raodah Nurul Jannah
Published: March 2024

Penyakit menular seks (PMS) adalah penyakit yang dapat ditularkan dari satu orang ke orang lain melalui hubungan seksual. PMS dapat dialami oleh para remaja, dewasa dan tua akibat perilaku seks yang menyimpang. Kasus ini dapat dicegah sejak dini sehingga tindakan pencegahan dapat dilakukan dengan mudah. Sosialisasi dilakukan dengan tujuan untuk meningkatkan pemahaman siswa dan siswi di SMA Negeri 5 Kendari mengenai penyakit menular seks dan bahayanya, serta bentuk atau tindakan pencegahan yang dapat dilakukan sejak dini. Dalam pelaksanaannya sosialisasi dilakukan secara tatap muka bersama guru maupun siswa dan siswi SMA Negeri 5 Kendari, serta pemberian leaflet berisi informasi tentang PMS. Berdasarkan hasil sosialisasi yang telah dilaksanakan tersebut dapat disimpulkan bahwa sosialisasi dan pemberian informasi melalui leaflet dapat meningkatkan antusiasme dan pemahaman masyarakat mengenai pentingnya pengetahuan dan pola pikir untuk mencegah kasus penyakit menular seks di kalangan remaja.
EDUKASI MANFAAT TANAMAN OBAT KELUARGA (TOGA) UNTUK KESEHATAN GURU DAN MURID DI SMAS KARTIKA KENDARI
Authors: - Thamrin
Published: March 2024

Dengan adanya isu back to nature, penggunaan obat herbal dari Taman Obat Keluarga (TOGA) menjadi semakin populer karena harganya yang lebih murah dan efek samping yang lebih sedikit dibandingkan obat tradisional. Keuntungan penggunaan obat herbal adalah memiliki lebih dari satu efek farmakologis, lebih mudah diperoleh, lebih mudah digunakan, dan lebih tepat untuk berbagai kelainan metabolisme dan genetik. Tujuan pengabdian yaitu untuk meningkatkan pengetahuan guru dan murid mengenai kapulaga dan kayu manis merupakan jenis tanaman yang dapat dibidudaya pada TOGA serta manfaatnya terhadap kesehatan. Kegiatan pengabdian dilakukan dengan metode sosialisasi dan edukasi tentang khasiat TOGA secara ilmiah, penanaman TOGA, dan pengolahan TOGA. Edukasi dilakukan dengan mengenalkan khasiat kapulaga dan kayu manis sebagai tanaman obat. Kegiatan pengabdian secara keseluruhan dapat berjalan baik dan konduksif, hal ini terlihat banyak pertanyaan yang diajukan guru dan murid mendapatkan pengetahuan baru mengenai jenis tanaman kapulaga dan kayu manis.