bluuebunny/crossref_metadata_2025 huggingface dataset:
Robust Optimum Life-Testing Plans under Progressive Type-I Interval Censoring Schemes with Cost Constraint
Authors: Zhou Xiaodong , Wang Yunjuan , Yue Rongxian
Published: May 2022

This paper considers optimal design problems for the Weibull distribution, which can be used to model symmetrical or asymmetrical data, in the presence of progressive interval censoring in life-testing experiments. Two robust approaches, Bayesian and minimax, are proposed to deal with the dependence of the D-optimality and c-optimality on the unknown model parameters. Meanwhile, the compound design method is applied to ensure a compromise between the precision of estimation of the model parameters and the precision of estimation of the quantiles. Furthermore, to make the design become more practical, the cost constraints are taken into account in constructing the optimal designs. Two algorithms are provided for finding the robust optimal solutions. A simulated example and a real life example are given to illustrate the proposed methods. The sensitivity analysis is also studied. These new design methods can help the engineers to obtain robust optimal designs for the censored life-testing experiments.
Ab Initio Computations of O and AO as well as ReO2, WO2 and BO2-Terminated ReO3, WO3, BaTiO3, SrTiO3 and BaZrO3 (001) Surfaces
Authors: Eglitis Roberts I. , Purans Juris , Popov Anatoli I. , Bocharov Dmitry , Chekhovska Anastasiia , Jia Ran
Published: May 2022

We present and discuss the results of surface relaxation and rumpling computations for ReO3, WO3, SrTiO3, BaTiO3 and BaZrO3 (001) surfaces employing a hybrid B3LYP or B3PW description of exchange and correlation. In particular, we perform the first B3LYP computations for O-terminated ReO3 and WO3 (001) surfaces. In most cases, according to our B3LYP or B3PW computations for both surface terminations BO2- and O, AO-terminated ReO3, WO3, BaTiO3, SrTiO3 and BaZrO3 (001) surface upper layer atoms shift downwards, towards the bulk, the second layer atoms shift upwards and the third layer atoms, again, shift downwards. Our ab initio computes that ReO3, WO3, BaTiO3, SrTiO3 and BaZrO3 (001) surface Γ-Γ bandgaps are always smaller than their respective bulk Γ-Γ bandgaps. Our first principles compute that B-O atom chemical bond populations in the BaTiO3, SrTiO3 and BaZrO3 perovskite bulk are always smaller than near their BO2-terminated (001) surfaces. Just opposite, the Re-O and W-O chemical bond populations in the ReO3 (0.212e) and WO3 (0.142e) bulk are slightly larger than near the ReO2 and WO2-terminated ReO3 as well as WO3 (001) surfaces (0.170e and 0.108e, respectively).
Adverse Effects of Perfluorooctane Sulfonate on the Liver and Relevant Mechanisms
Authors: Wang Pingwei , Liu Dongge , Yan Shuqi , Cui Jiajing , Liang Yujun , Ren Shuping
Published: May 2022

Perfluorooctane sulfonate (PFOS) is a persistent, widely present organic pollutant. PFOS can enter the human body through drinking water, ingestion of food, contact with utensils containing PFOS, and occupational exposure to PFOS, and can have adverse effects on human health. Increasing research shows that the liver is the major target of PFOS, and that PFOS can damage liver tissue and disrupt its function; however, the exact mechanisms remain unclear. In this study, we reviewed the adverse effects of PFOS on liver tissue and cells, as well as on liver function, to provide a reference for subsequent studies related to the toxicity of PFOS and liver injury caused by PFOS.
In Vitro Effects of Lemon Balm Extracts in Reducing the Growth and Mycotoxins Biosynthesis of Fusarium culmorum and F. proliferatum
Authors: Uwineza Pascaline Aimee , Urbaniak Monika , Bryła Marcin , Stępień Łukasz , Modrzewska Marta , Waśkiewicz Agnieszka
Published: May 2022

The objectives of this research were to obtain the extracts of lemon balm (Melissa officinalis) using supercritical CO2 (SC-CO2) and methanol as co-solvent and evaluate the antifungal activity of those extracts against two selected strains of Fusarium species (Fusarium culmorum and Fusarium proliferatum). The extraction conditions were set at 40 and 60 °C and 250 bar. The obtained extracts were characterized in terms of antifungal activity on potato dextrose agar media (PDA). The results showed that the extraction parameters had different effects on mycelium growth and mycotoxins biosynthesis reduction. All studied lemon balm extracts (1, 2.5, 5, 7.5, and 10%) inhibited the growth of F. proliferatum and F. culmorum mycelia compared to the control. The lemon balm extracts significantly reduced ergosterol content and synthesized mycotoxins in both tested strains. These findings support the antifungal activity of lemon balm extracts against F. proliferatum and F. culmorum. However, more research on other Fusarium species is needed, as well as in vivo applications, before considering lemon balm extracts as a natural alternative to synthetic fungicides.
Human Retrovirus Genomic RNA Packaging
Authors: Hanson Heather M. , Willkomm Nora A. , Yang Huixin , Mansky Louis M.
Published: May 2022

Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles. Retroviral RNA packaging requires RNA export of the unspliced genomic RNA from the nucleus, translocation of the genome to virus assembly sites, and specific interaction with Gag, the main viral structural protein. While some aspects of the RNA packaging process are understood, many others remain poorly understood. In this review, we provide an update on recent advancements in understanding the mechanism of RNA packaging for retroviruses that cause disease in humans, i.e., HIV-1, HIV-2, and HTLV-1, as well as advances in the understanding of the details of genomic RNA nuclear export, genome translocation to virus assembly sites, and genomic RNA dimerization.
Dating the Emergence of Human Endemic Coronaviruses
Authors: Forni Diego , Cagliani Rachele , Pozzoli Uberto , Mozzi Alessandra , Arrigoni Federica , De Gioia Luca , Clerici Mario , Sironi Manuela
Published: May 2022

Four endemic coronaviruses infect humans and cause mild symptoms. Because previous analyses were based on a limited number of sequences and did not control for effects that affect molecular dating, we re-assessed the timing of endemic coronavirus emergence. After controlling for recombination, selective pressure, and molecular clock model, we obtained similar tMRCA (time to the most recent common ancestor) estimates for the four coronaviruses, ranging from 72 (HCoV-229E) to 54 (HCoV-NL63) years ago. The split times of HCoV-229E and HCoV-OC43 from camel alphacoronavirus and bovine coronavirus were dated ~268 and ~99 years ago. The split times of HCoV-HKU1 and HCoV-NL63 could not be calculated, as their zoonoticic sources are unknown. To compare the timing of coronavirus emergence to that of another respiratory virus, we recorded the occurrence of influenza pandemics since 1500. Although there is no clear relationship between pandemic occurrence and human population size, the frequency of influenza pandemics seems to intensify starting around 1700, which corresponds with the initial phase of exponential increase of human population and to the emergence of HCoV-229E. The frequency of flu pandemics in the 19th century also suggests that the concurrence of HCoV-OC43 emergence and the Russian flu pandemic may be due to chance.
Leishmania tarentolae as an Antigen Delivery Platform: Dendritic Cell Maturation after Infection with a Clone Engineered to Express the SARS-CoV-2 Spike Protein
Authors: Varotto-Boccazzi Ilaria , Garziano Micaela , Cattaneo Giulia Maria , Bisaglia Beatrice , Gabrieli Paolo , Biasin Mara , Manenti Alessandro , Rubolini Diego , Clerici Mario , Montomoli Emanuele , Zuccotti Gian Vincenzo , Trabattoni Daria , Epis Sara , Bandi Claudio
Published: May 2022

Background: Protozoa of the genus Leishmania are characterized by their capacity to target macrophages and Dendritic Cells (DCs). These microorganisms could thus be exploited for the delivery of antigens to immune cells. Leishmania tarentolae is regarded as a non-pathogenic species; it was previously used as a biofactory for protein production and has been considered as a candidate vaccine or as an antigen delivery platform. However, results on the type of immune polarization determined by L. tarentolae are still inconclusive. Methods: DCs were derived from human monocytes and exposed to live L. tarentolae, using both the non-engineered P10 strain, and the same strain engineered for expression of the spike protein from SARS-CoV-2. We then determined: (i) parasite internalization in the DCs; and (ii) the capacity of the assayed strains to activate DCs and the type of immune polarization. Results: Protozoan parasites from both strains were effectively engulfed by DCs, which displayed a full pattern of maturation, in terms of MHC class II and costimulatory molecule expression. In addition, after parasite infection, a limited release of Th1 cytokines was observed. Conclusions: Our results indicate that L. tarentolae could be used as a vehicle for antigen delivery to DCs and to induce the maturation of these cells. The limited cytokine release suggests L. tarentolae as a neutral vaccine vehicle that could be administered in association with appropriate immune-modulating molecules.
Omicron Infection Evokes Cross-Protection against SARS-CoV-2 Variants in Vaccinees
Authors: Anichini Gabriele , Terrosi Chiara , Gandolfo Claudia , Gori Savellini Gianni , Fabrizi Simonetta , Miceli Giovanni Battista , Franchi Federico , Cusi Maria Grazia
Published: May 2022

Due to the rapid global spread of the Omicron (B.1.1.529) variant, efforts to scale up COVID-19 booster vaccination have been improved, especially in light of the increasing evidence of reduced neutralizing antibody (NT Ab) over time in vaccinated subjects. In this study, neutralizing antibody responses against the Wild-Type, Delta, and Omicron strains were evaluated among vaccinees, both infected with Omicron or uninfected, and non-vaccinated subjects infected with Omicron. The aim of the study was to compare the cross-protective humoral response to the variant strains induced by vaccination and/or Omicron infection. The results showed a significant difference in the neutralizing antibody response between the vaccinees and the Omicron-infected vaccinated subjects against the three tested strains (p < 0.001), confirming the booster effect of the Omicron infection in the vaccinees. By contrast, Omicron infection only did not enhance the antibody response to the other variants, indicating a lack of cross-protection. These results suggest the importance of updating the current formulation of the SARS-CoV-2 vaccine to protect people against the Omicron subvariants. A specific Omicron vaccine, administered as a booster for the previously adopted mRNA vaccines, may protect against a wider range of SARS-CoV-2 variants. However, it is unlikely that the Omicron vaccine alone would be able to protect non-vaccinated subjects against other circulating variants.
Cellular Immune Response after Vaccination with an Adjuvanted, Recombinant Zoster Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients
Authors: Koldehoff Michael , Horn Peter A. , Lindemann Monika
Published: May 2022

Hematopoietic stem cell transplant (HSCT) recipients have a high risk of developing primary varicella-zoster virus (VZV) infection and reactivation. VZV vaccination may prevent infection and reactivation. In the current study, recipients of allogeneic HSCT (34 females, 45 males) were vaccinated with adjuvanted, recombinant zoster vaccine Shingrix™, which contains the VZV glycoprotein E. Cellular immunity against various VZV antigens was analyzed by interferon-gamma ELISpot. Peripheral blood mononuclear cells (PBMC) of recipients with versus without prior shingles (n = 36 and n = 43, respectively) showed approximately twofold higher VZV-specific responses prior to and post vaccination. After the first and second vaccination, ELISpot responses towards the glycoprotein E were significantly higher in males versus females (median of spots increment 18 versus 1 and 17 versus 4, respectively, p ≤ 0.02 each). Multivariate analysis showed that shingles and sex both impacts significantly on VZV immunity. Whereas vaccination-induced changes could hardly be detected after stimulation with a whole VZV antigen, there was a significant increase in responses towards glycoprotein E after vaccination (p < 0.005). These data indicate that vaccination with Shingrix™ augmented cellular, VZV-specific immunity in HSCT recipients. Shingles and male sex could both be identified as factors leading to increased immunity.
Optimal Control of Electrified Powertrains in Offline and Online Application Concerning Dimensioning of Li-Ion Batteries
Authors: Deufel Felix , Gießler Martin , Gauterin Frank
Published: May 2022

Various energy management systems (driving strategies) have been developed to improve the efficiency of electrified vehicle drives. These include strategies from the field of offline optimization to determine the theoretical optimum for a given system, as well as online strategies designed for an on-board application in the vehicle. In this paper, investigations are performed on an SUV electrified by a 48 V hybrid system in P14 topology regarding both offline and online strategies. To calculate the global optimum, the performance of Dynamic Programming (DP) compared to an Equivalent Consumption Minimization Strategy (ECMS) with an iteratively determined equivalence factor is shown. Furthermore, with regard to online energy management strategies (EMS), it is presented how a predictive Online ECMS achieves additional fuel savings compared to a robust, non-predictive implementation. The simulation-based vehicle development allows detailed investigations regarding interactions between battery requirements and EMS. In this context, it is shown how various battery capacities are exploited by the discussed EMS.
Study of the Behavior of Alkalinities Predicted by the AM2 Model
Authors: Campos-Rodríguez Armando , Zárate-Navarro Marco A. , Aguilar-Garnica Efrén , Alcaraz-González Víctor , García-Sandoval Juan Paulo
Published: May 2022

Anaerobic digestion (AD) is an efficient wastewater bioprocess, suitable for treating agroindustrial residues with high organic loads and characterized by both a low environmental impact and energy generation. This process is conformed by several chemical and biological reactions in an oxygen free atmosphere, that degrades high molecular weight organic compounds into carbon dioxide and methane mainly but also into traces of hydrogen and ammonia. This process is potentially unstable to volatile fatty acids (VFA), and the alkalinity. variations and is satisfactorily described by the non-linear AM2 model. In this contribution, the AM2 model is modified to include a more general expression for the pH, a cheap and continuous measurement, and also to add more detail in the interactions of the VFA, bicarbonates, and the alkalinity, key factors in the process stability. The stability of the AM2 modified model is explored through a rigorous bifurcation analysis that identifies unstable operation zones and viability of operation trajectories as a function of the dilution rate. Finally, an experimental validation is carried out to show the feasibility and accuracy of the proposed modifications.
Sociodemographic Influences on Perceived Stress during Pregnancy: Results from the CCREOH Environmental Epidemiologic Study, Suriname
Authors: Koendjbiharie Aloysius Ph. , Hindori-Mohangoo Ashna D. , Zijlmans Wilco C. W. R. , Shankar Arti , Abdoel Wahid Firoz Z. Abdoel , Covert Hannah H. , Lichtveld Maureen Y. , Drury Stacy S.
Published: May 2022

Screening for prenatal stress is not routine in Suriname, despite its significant impact on maternal and newborn health. This study assessed the prevalence of high perceived prenatal stress and its sociodemographic predictors in three geographic areas in Suriname. In this cross-sectional study, data from 1190 participants of the Caribbean Consortium for Research in Environmental and Occupational Health cohort study were analyzed. Cohen’s Perceived Stress Scale was completed during pregnancy to ascertain high perceived stress (cut-off score 20). The association between maternal sociodemographic factors and high perceived stress was examined using the chi-square test and logistic regression models; 27.5% of all participants had high perceived stress with statistically significant lower rates in Nickerie (18.8%) compared with Paramaribo (29.8%; p = 0.001) and the Interior (28.6%; p = 0.019). Maternal sociodemographic factors moderated the difference between the Interior and Nickerie. Participants from Paramaribo had statistically significant higher odds of high perceived stress compared to those from Nickerie, independent of their age and educational level (adjusted OR = 1.94; 95% confidence interval 1.32–2.86). Perceived stress during pregnancy is predicted by sociodemographic factors. These findings identified target groups for interventions in Suriname. Policy makers should consider integrating perceived stress assessment as a routine part of prenatal care.
INTERNATIONALIZATION OF UNIVERSITIES THROUGH PARTICIPATION IN THE ERASMUS + KA2 PROJECTS
Authors: Grynova M. , Kohut I.
Published: May 2022

The article is devoted to highlighting the specifics of the role of the ERASMUS+ program in meeting the educational needs of modern Ukrainian students. It is concluded that the participation of Ukrainian students in such programs reflects their desire to internationalize the educational space, expand their horizons and form a system of various competencies within the European integration of Ukrainian education. The article unfolds the direction of scientific research on the effectiveness of student participation in international projects. In particular, it dwells on the issues on which modern projects within the ERASMUS+ framework are based. It also proceeds to outlining the technological professional competencies, which enable the integration of the younger generation into the world’s educational space in a timely and effective manner. The summary of topical projects in which students of Poltava V. G. Korolenko National Pedagogical University take part is presented in this work. In particular, it is described how international programs ‘Writing for inclusion’ 2020-1-ES01-KA201-081827, ‘Care in Education’, and ‘Horizon Europe Program’ are implemented.

The system of functioning and integration of educational institutions in the process of participation in international projects is described. Vivid examples of the interaction of higher and secondary educational institutions are presented, aimed at implementing advanced concepts of students’ care, multicultural development, and integration into the international community. The current difficulties in the subjects of educational and professional activities related to the use of advanced technologies and means of e-learning and interaction are described. The role of participation in international projects to increase the competence and competitiveness of modern specialists is determined.

It is concluded that the participation of students in ERASMUS + provides multicultural and international dialogue in the implementation of the latest strategies for preschool and school education, the implementation of art therapy in the educational process, and the usage of the vast potential of art for teaching students.
THE CULTURAL AND LINGUISTIC DIMENSIONS OF METAPHORS IN BILINGUAL TEACHER EDUCATION
Authors: Trentinne Benko E.
Published: May 2022

In Europe, the number of early bilingual/multilingual or CLIL (Content and Language Integrated Learning) programmes is increasing. They offer ideal circumstances for learners of various linguistic and cultural backgrounds, foreigners and native speakers alike. Awakening to languages, building positive attitudes toward other nations and developing openness, tolerance, and intercultural awareness can occur naturally in the early years when professional support and conditions are provided. Teachers working in bilingual or plurilingual educational contexts need a wide range of unique competencies. ELTE University, Faculty of Primary and Pre-school Education is one of the few institutions in Hungary providing early pre-service bilingual teacher training at a BA level since 2006. The article presents ELTE TÓK’s student teachers’ beliefs by investigating their metaphors of the effective CLIL practitioner, emphasising those with a linguistic and cultural dimension. Their metaphors prove that future teachers have adequate personal and professional competencies to support young learners’ plurilingual and multicultural development in the future.
FOLK FESTIVALS ORGANIZATION IN THE CHILDREN’S INSTITUTION OF HEALTHCARE AND RECREATION
Authors: Irkliienko V.
Published: May 2022

The article substantiates the expediency of using folk festivals in the educational work of children’s institution of healthcare and recreation for children’s personal development. The author reveals the process of folk festival organization and holding in the institution of children’s healthcare and recreation.
Avaliação de células DCX positivas no cérebro do primata Sapajus apella
Authors: Franco Edna Cristina Santos , Vitor da Silva Freitas Antonio
Published: May 2022

Introdução. A neurogênese no neocórtex de primatas é um campo de estudo a ser desvendado. Autores sugerem que novos neurônios provenientes da zona subventricular (SVZ) são adicionados em áreas corticais com funções cognitivas e associativas, mas não em áreas sensoriais primárias. Objetivos. Investigar a neurogênese em amostras de cérebro de primatas não-humanos da espécie Sapajus apella imunomarcadas com o anticorpo anti-DCX. Analisar qualitativa e quantitativamente a imunomarcação encontrada em diferentes regiões do encéfalo deste primata. Descrever as áreas com o maior número de células DCX positivas e relacionar esses achados com suas respectivas funções. Método. O estudo utilizou lâminas contendo secções coronais de cérebros de S. apella imunomarcadas com anticorpo anti-DCX. As lâminas foram analisadas utilizando microscópio óptico binocular. Locais onde a imunomarcação para anti-DCX foi positiva foram fotografadas e as células foram contadas. Resultados. Analisou-se 22 lâminas em microscopia ótica, das quais somente 5 possuíam células DCX positivas. Verificou-se 153 células DCX positivas. Foram identificados neuroblastos com morfologias distintas em diferentes regiões do encéfalo desse primata. A região subventricular foi a região onde foram encontradas a maior quantidade de neuroblastos. Foram encontrados neuroblastos também na região cortical, subcortical, no Estriado e no terceiro ventrículo. Conclusão. Células DCX positivas foram encontradas na região periventricular do ventrículo lateral e do terceiro ventrículo, como também na região cortical, subcortical e no estriado. A presença de tais células reforça a existência já descrita de uma corrente migratória rostral, como também da capacidade de interconexão entre áreas corticais presentes em primatas.
Trombólise venosa em paciente com Doença de Parkinson e DBS
Authors: Colodetti Zanandréa Leticia , De Aguiar Lima Luiza , Santos Machado Lara , Rodrigues Moreira Luiza , Colnago Demoner Giuliane , Lapa de Menezes Ana Carolina , Broseghini Barcelos Lorena , Maria Nunes Bassetti Elida , Rasseli Sfalsini Rúbia , Fiorot Junior José Antônio
Published: May 2022

Introdução. Este estudo aborda um caso de trombólise venosa em paciente com estimulação cerebral profunda (DBS). Relato de caso. Mulher, 57 anos, com hemiparesia completa à direita, disartria, NIHSS 12 e Glasgow 15. Antecedentes de doença de Parkinson com diagnóstico aos 37 anos, e tratamento com DBS no núcleo subtalâmico bilateral, em uso de L-dopa/carbidopa e entacapone. Realizada trombólise venosa com 4 horas e 40 minutos do início dos sintomas. No dia seguinte apresentava NIHSS 11 e Glasgow 15. Conclusão. Ainda, não há critérios estabelecidos na literatura que garantam a segurança, nem as contraindicações que inviabilizem a trombólise venosa em portadores de DBS. No entanto, o uso dessa terapia no caso apresentado se mostrou eficaz e segura.
A Comparison between English and Makassarese Politeness System: A Comparative Study
Authors: Syarifuddin Nurjannah , Yassi Abdul Hakim , Sahib Harlinah
Published: May 2022

This study aimed to describe the dominant variable that affected in use of politeness systems and to analyse the process of native speakers of English and Makassar in using the politeness system through conversations. The method of this study was the quantitative method and used statistic frequency. In this study, there are two variables that affected politeness. These data were processed based on the identification, classification, description, grouping, and calculation. Yassi’s theoretical framework found there are six politeness strategies. The strategies are deference in non-kinship, deference in kinship, intimacy in non-kinship, intimacy in kinship, hierarchy in non-kinship, and hierarchy in kinship. Based on his theory, age and seniority were the most affected in use politeness. The researcher found the difference in this study. The research finding indicates that the two variables do not affected the politeness systems of English but it is affected for Makassarese politeness systems. The English and Makassarese were different countries, so the politeness systems were also different. The English used FTA in doing communications and Makassarese has positive and negative politeness. The educational background is the dominant variable in use negative politeness and the age affect in use positive politeness for Makassarese.
Exploring The Challenges of Communicative Language Teaching in Indonesian Context from a Constructivist Perspective
Authors: Hakim Izzuddin
Published: May 2022

A communicative approach has been included in Indonesia's English curriculum since the introduction of the 1984 Curriculum. However, despite its popularity, CLT (Communicative Language Teaching) posited some cultural constraints. These constraints are caused by different views of the learning and teaching process in different cultures. This study explores the challenges of implementing such a teaching approach from a constructivist point of view. The primary aim of this article is to provide insightful information about those challenges which may, then, contribute to a deeper understanding of the issue. The descriptive qualitative approach was used in this study. The study concludes that cultural constraints to the implementation of CLT in the Indonesian context do not necessarily come from cultural aspects. Using a constructivist paradigm, this essay provides an alternative explanation on why students are reluctant to engage in a communicative approach in the Indonesian context: (1) the failure of representation to occur in the teaching instructions and teaching materials during the learning process, and (2) identity-caused reluctance to communicative competence.
THE ARRANGEMENT OF THE DELIVERY OF FOOD AND ESSENTIAL GOODS TO THE REMOTE AREAS USING A MOBILE SHOP CAR
Authors: Belozerova I. , Eremina L.
Published: May 2022

The relevance of the chosen topic is due to the need to solve an important socio-economic problem of providing food and essential goods to the population of remote areas. One of the solutions to this problem is the delivery of goods to consumers with using a mobile shop car.
TO THE ISSUE OF ASSESSING CUSTOMER SATISFACTION WITH CAR SERVICE SERVICES
Authors: Sedov A. , Konev A.
Published: May 2022

We considered the issue of assessing customer satisfaction as one of the factors for the success of the car service.
ANALYSIS OF ELEMENTS OF CONSTRUCTIVE SAFETY OF VEHICLES APPLIED CURRENTLY
Authors: Zelikova N. , Zakurdaeva K. , Strukov Yu. , Denisov G. , Zelikov V.
Published: May 2022

The article presents an analysis of the structural safety elements of cars that are used in the construction of vehicles. A description of the elements that affect the level of vehicle safety is given. The influence of structural safety elements of a car on the likelihood of an emergency is considered.
A MODALIDADE DO PREGÃO ELETRÔNICO NAS LICITAÇÕES DE SERVIÇOS TERCEIRIZADOS NO GOVERNO DO ESTADO DE RONDÔNIA PÓS DECRETO FEDERAL Nº 10.024/2019
Authors: ARAUJO PEIXOTO VLADMYR , MICHAEL VIDEIRA DOS SANTOS ADRIANO
Published: May 2022

This article aims to analyze Federal Decree 10,024/2019, which made the way to acquire goods and services mandatory, reversing phases in the bidding processes, shortening deadlines, increasing competitiveness, verifying its applicability within the State Government of Rondônia. In such a way that the new federal regulation brought greater speed and efficiency in the provision of public services. For this purpose, the institute of public bidding will be addressed in view of its constitutional and infraconstitutional requirement, since the auction is a type of bidding of the lowest price type, carried out in person or electronically, under the constitutional principle of morality and efficiency in its key element to produce well, with quality and with less expense, considering that the whole community benefits. The methodological procedures used were: from the point of view of its objectives, a descriptive research with the method of deductive approach, being a qualitative scientific study, with data analysis and statistics of electronic auctions carried out by the Superintendence of Bidding of the State Government of Rondônia.
Normalising the use of electronic evidence
Authors: Ontanu Elena Alina
Published: May 2022

Society is increasingly relying on technology for daily business and activities. This is linked to a rapid update in technology use and digitalisation with courts being called to consider new forms of evidence in an electronic environment and/or rely on technology for the taking of evidence. The normative framework concerning electronic evidence remains fragmented while various legislative projects are ongoing. In this process the global pandemic accelerated attention for technology solutions and their integration in the handling of court claims. In the EU, the reviewed Taking of Evidence Regulation (Regulation 2020/1783) addresses some of the necessary aspects related to electronic evidence and cooperation between authorities. Other elements are covered by cross-sectorial EU legislation such as regulations concerning data protection or electronic identification and trust services. New regulation proposals concerning the digitalisation of judicial cooperation and communication in cross-border procedures are set to address some of the legislative gaps in the near future as well as support the developments of necessary technology. However, the overall existing legislation is only partly sufficient for providing a comprehensive framework and does not provide much guidance in the process of considering metadata or assessing electronic evidence.
Norm, normal and disruption
Authors: Mohr Richard , Contini Francesco , Branco Patrícia
Published: May 2022

The eleven papers in this special issue analyze how different sources of disruption collide with normality, the consequences on individual, social and institutional life, and efforts to re-establish the old or to create a new normal. They arose from a series of online seminars in September and October 2020 investigating normality, disruption and normalization in the wake of the current environmental, technological, epidemiological and socio-economic shocks. Disruption is a window into the underlying fabric of social arrangements. It allows us to investigate the concept of normality and its implications, the tensions and conflicts between economic, social, legal and technological means used to re-establish normality. Technologies of normalization may paradoxically cause further disruptions. Human dignity is a landmark value in these inquiries. The introduction and the papers suggest possible measures to anticipate disruptions and consequent harms. They alert us to the risks to human dignity arising from disruption and from attempts to reimpose forms of normality.
“La caza del autor”: autoría e imagen en las ficciones autorales de Emma de la Barra/César Duayén
Authors: Boiola Karina
Published: May 2022

En este artículo se analizan los vínculos entre autoría e imagen en las ficciones autorales que surgen de las notas y reseñas periodísticas que acompañaron la publicación de la primera novela de la escritora rosarina Emma de la Barra, Stella (1905), entre 1905 y 1908. Publicada bajo el seudónimo César Duayén, que la escritora mantendría a lo largo de toda su trayectoria, la novela se convirtió en el primer best-seller de nuestra literatura nacional. Muchos de esos artículos, publicados en medios como La Nación, Caras y Caretas, P.B.T y El Diario, incluyeron fotografías y caricaturas de De la Barra, las cuales moldearon, en gran medida, su perfil autoral. Se postula que la autora tuvo un rol activo en la construcción de esas representaciones, a través de las estrategias publicitarias que desarrolló en torno a la publicación de Stella y el misterio de su pseudónimo.
“El mercado es como la marea”. Editoriales, editores/as y literatura juvenil en Argentina
Authors: Pates Giuliana
Published: May 2022

Situándonos en la perspectiva de la Sociología de la literatura, entendemos que las novelas no son solo producciones textuales, sino también materiales. Para analizarlas, es necesario dar cuenta de las mediaciones que intervienen para que un texto se convierta en un libro. En este marco, en el presente artículo, haremos foco en las figuras de las editoriales y de los/as editores/as como actores fundamentales del campo literario, en particular, de la edición de best sellers juveniles. Nos interesará reconstruir la formación de la literatura juvenil dentro del mercado editorial argentino y caracterizar los modos de edición de novelas juveniles contemporáneas que circulan por fuera de las escuelas. A partir de la experiencia de editores/as del sector, que relevamos en entrevistas en profundidad, analizaremos sus perfiles como editores/as y sus formas de gestión editorial, así como las interfaces entre las políticas editoriales y la formación de un nuevo público lector.
El hacedor o la paratopía creadora
Authors: Adur Nobile Lucas Martín
Published: May 2022

A lo largo de la década del cincuenta, y especialmente a partir de 1955, la figura de Borges se consolida como centro del campo literario argentino, con cargos oficiales (director de la Biblioteca Nacional, profesor de la Universidad de Buenos Aires) y una cada vez mayor notoriedad pública, dentro y fuera del país. El hacedor (1960) es el primer libro que el escritor publica después de su canonización y, en este sentido, puede pensarse como una respuesta a un problema recurrente en la trayectoria de muchos escritores, aunque rara vez planteado de modo explícito: ¿cómo seguir escribiendo después de la consagración? El hacedor tematiza la construcción de una figura de autor —como es evidente desde el título y en textos como “Poema de los dones” y “Borges y yo”—, a partir de la recuperación de datos biográfico-contextuales que se inscriben y reelaboran en la obra. Estos elementos que participan, a la vez, del texto y del contexto han sido denominados por Maingueneau embragues paratópicos. La ceguera y la fama, dos de los motivos más recurrentes en el volumen, funcionan como embragues paratópicos, que posibilitan un des-centramiento del escritor, la construcción de un posicionamiento inestable, donde el máximo poder coexiste con la máxima debilidad. Este lugar de enunciación paradójico-paratópico es lo que le permite seguir escribiendo después del éxito.
El pensamiento, el juego y lo terrible de la escritura
Authors: González Darío
Published: May 2022

Este artículo vuelve sobre la relación entre pensamiento, juego y escritura. Se parte de la reflexión en torno al aparente contraste entre la inocencia del juego poético y la peligrosidad del lenguaje, para interrogar dos consideraciones que, aunque íntimamente relacionadas, suelen formularse de modo diferente: por un lado, la poesía como una actividad inocente que se despliega en el ámbito de lo peligroso; por otro, la escritura como un juego vano en el que se pone en juego algo terrible. La poesía es abordada como un logos excéntrico, que se resiste al devenir-razón de la palabra. Se aborda la pregunta acerca de la relación entre el arte y la seriedad de la vida. Por último, se ensaya una consideración acerca del tiempo del juego en la poesía, o incluso, del tiempo considerado como juego.
La buena pipa: juego y repetición
Authors: Moscardi Matías
Published: May 2022

En este artículo, tomo como punto de partida la descripción del “fort-da” que Freud realiza en Más allá del principio de placer, para pensar el significado del juego definido en esos términos. A su vez, propongo expandir las relaciones del juego –tal y como lo concibe Freud– con el ritmo –la rima–, la música y la danza; pero también con el chiste y el cuento como géneros literarios.
The Impact of Image Enhancement and Transfer Learning Techniques on Marine Habitat Mapping
Authors: SHAKER Ehab , BAKER Mohammed Rashad , MAHMOOD Zuhair
Published: May 2022

Marine habitat mapping is primarily done to monitor and preserve underwater ecosystems. Images captured in a marine environment suffer from acidification, pollutions, waste chemicals, and lighting conditions. Human beings are progressing fast in terms of technology and are also responsible for the degradations of ecosystems, both marine and land habitats. Marine biologists possess a lot of data for the underwater environment, but it is hard to analyze, and the task becomes tiresome. Automating this process would help marine biologists quickly monitor the environment and preserve it. Our research focuses on coral reef classification and two critical aspects, i.e., Image enhancement and recognition of coral reefs. Image enhancement plays an essential role in marine habitat mapping because of the environment in which images are taken. The literature contains many image enhancement techniques for underwater. The authors want to determine whether a single image enhancement technique is suitable for coral reefs. Four image enhancement techniques based on an extensive literature review are selected. We have used DenseNet-169 and MobileNet for image classification. It has been reported that DenseNet-169 has excellent results for coral reefs classification. Histogram techniques combined with DenseNet-169 for classification resulted in higher classification rates.
Silica-based planar lightwave circuits with high resistance against blue light for visible-light application
Authors: Fujiwara Yuji , Sakamoto Junji , Katayose Satomi , Hashimoto Toshikazu , Watanabe Kei
Published: May 2022

We propose two novel types of waveguide, Zr-doped and non-doped silica, for high-power visible-light applications. We fabricated these waveguides and investigated their resistance against blue light. Both Zr-doped and non-doped silica waveguides showed one order of magnitude higher resistance against blue light compared with conventional Ge-doped silica waveguides. A comparison of their resistances indicated that Zr-doped silica waveguides are useful against blue light powers up to about 20 mW and non-doped silica waveguides have more potential for higher resistance against blue light powers over 20 mW.
Silenciamento do nome Voldemort em 'Harry Potter': apontamentos sobre discurso e poder
Authors: Da Silva Junior Joseeldo
Published: May 2022

Este artigo visa analisar o discurso de silenciamento e as relações de poder na obra Harry Potter. Como se sabe, a narrativa J. K Rowling é um dos maiores fenômenos da literatura contemporânea, vindo a se tornar objeto de estudo nos diversos campos do saber. Neste estudo, a partir da Análise do Discurso “com” Foucault, propomos perscrutar a pertinência das noções de discurso e poder, tomando como problema o fenômeno do silenciamento promovido ao nome Voldemort – o antagonista da trama. Durante toda a série o nome do vilão é frequentemente substituído pelo qualificações como “Aquele-Que-Não-Deve-Ser-Nomeado” ou “Você-Sabe-Quem”, como estratégia para evitar a sua nomeação, cabendo apenas a Harry e Dumbledore resistirem e demarcarem posição contra o bruxo. As análises apontaram para uma política de silêncio em que opera o medo, como se Voldemort representasse, em outro contexto, a figura ocidental do diabo, daí um dos motivos do apagamento de seu nome. Quanto a metodologia deste estudo, trata-se de uma pesquisa de cunho qualitativo com viés descrito-interpretativo, que toma como arcabouço as teorizações de Michel Foucault.
Ch-ch-ch-changes: A influência de David Bowie na franquia cinematográfica do filme "Labirinto" de Jim Henson
Authors: McDonald Dean-Liathine
Published: May 2022

Há quase quarenta anos, o filme Labirinto, dirigido por Jim Henson, encontra facilmente seu lugar em nossos lares. Em 2016, tornado célebre, numerosas revistas chegaram inclusive a tratá-lo como um filme cult por ocasião do lançamento da edição especial de seu 30º aniversário. No entanto, a estranha mistura que essa popularidade perpétua produziu também se tornou difícil de categorizar. Com efeito, embora Henson tenha feito do projeto um filme maravilhoso em um mundo secundário, mudanças inesperadas se lhe foram impostas, e, sobretudo, depois que David Bowie aceitou o papel de antagonista na história. Assim como a heroína é transformada ao atravessar o labirinto, as últimas alterações fizeram do filme algo, ao mesmo tempo, maduro e único em seu gênero. Por outro lado, quando essas mudanças são consideradas com os elementos transmidiáticos ao redor do filme, este se revela mais alinhado com outro gênero do insólito, ainda pouco estudado, que começava a conhecer algum sucesso nos anos 80: a Fantasia urbana. Assim, com as pesquisas recentes sobre a Fantasia e a Fantasia urbana como ponto de apoio, este artigo analisa a influência de Bowie não somente na produção do filme Labirinto, mas também no roteiro, no cenário e na trilha sonora.
A Chatbot Application by using Natural Language Processing and Artificial Intelligence Markup Language
Authors:   Software Engineer, Rapipay Fintech Private Limited. Noida (U.P), India., Arya Vanshika , Khan Rukhsar ,   An Intern at DXC, Bengaluru (Karnataka), India., Aggarwal Prof. Mukul ,   Assistant Professor, KIET Group of Institutions, Muradnagar (U.P), India.
Published: May 2022

A program which helps in making conversation with the help of textual methods is referred to as chatbot. Chatbot helps in responding to a message quickly and that too without human intervention. Startups are inventing thousands of chatbots in order to provide a better service and keep their customers busy by a kind and simple conversation. It also helps in providing far better services to customers and helps in buying products. It takes an input from the user in the form of keywords, and it matches those keywords in its data-set to give out the corresponding output saved in it. It gives all the possible answers related to user queries. Since, most of the times like during pandemic, we cannot go outside and cannot meet people, it is an interactive way to get to know about how world is dealing with it. Chatbots exploits AI and ML platforms. Chatbots are becoming popular day by day in this modern era, they are being used in business groups and helps in reducing costs and can help in providing one to many communications that means it can handle multiple customers at same time. Chatbots need to be as efficient as possible.
System-on-System Competition in Defense Innovation
Authors: Dew Nicholas , Lewis Ira
Published: May 2022

Defense innovation systems (DIS) have become an important analytic concept in defense policy circles in recent years. DIS are networks of interacting agents involved in the generation, diffusion, and utilization of defense-related technologies supported by local institutional infrastructures. This notion can be a valuable addition to one’s arsenal of tools for understanding aspects of great power competition between the United States and China. The DIS construct draws attention to competition between the United States and China being fundamentally a contest between different innovation systems. This adds an important perspective to policy debates because it broadens the analysis of competition away from particular elements and toward the overall systems involved, including global technological systems, dual-use technologies, and civilian elements that are important components of nearly all innovation systems. Furthermore, while U.S. industrial policy may have historically hidden it, the DIS construct draws attention to the intensive management and networking activities by U.S. Department of Defense elements involved in organizing the generation, diffusion, and utilization of defense-related technologies. For China, the DIS construct helps shed a bright light on the civilian-military fusion that has been a bedrock of China’s international competitive strategy.
Impact of Crumb Rubber on Stabilization of Soils
Authors: Chowdhury Chotan
Published: May 2022

The quantity of waste tires, an undesirable surplus, has been growing each year. The probabilities to take away scrap rubber tires to utilize these as a soil stabilizer, which increases the bearing strength of soil and also improved the bearing capacity of the soil. Trouble related to the socio-financial improvement of a rustic is waste tire decomposition. It has been a hard job to dispose of waste rubber tires safely. In this work, the opportunity of the usage of powder form of rubber tires as a supplement to enhance the shear strength of soft soil became evaluated. The bearing capacity of stabilized soils had been an advanced way of means of growing chances of crumb rubber. Besides this improvement, the effects of this kind of stabilizer and its distinctive portions on effluent traits also are analyzed. The addition of processed waste tires which are powdered form in each soil suggests acceptable adjustments in permeability. This research paper affords the improvement of soils the usage of fragmented waste tires at various proportions. The compressibility and unconfined compression strength of soil had been made used to measure the conduct & overall execution of the improved soils. Along with the test carried out with the soil Specimen, it became found, the highest dry unit weight and most efficient water content, material lower together with a boom in the proportion of stabilizer on soils. The value of shear strength increased with an increase in the proportion of mixtures and the highest values had been found at percentages of 5% & 15% for the specimens, S-1& S-2 severally.