bluuebunny/crossref_metadata_2025 huggingface dataset:
Uso del ECG endocavitario en la canalización de vías centrales
Authors: Luis Clemente Armendariz  , Ana Casimiro Erviti  , Mikel Batllori Gastón
Published: April 2021

La canalización de vías centrales supone, hoy en día, una práctica habitual en el ámbito de la Anestesiología. Mediante este artículo queremos presentar el uso del ECG endocavitario como método alternativo para guiar la adecuada colocación del catéter. Se trata de una técnica útil, inocua y fácil de llevar a cabo. Acompañamos el texto de un vídeo explicativo para facilitar la comprensión de la técnica. ABSTRACT Intracavitary ECG practice in the insertion of central venous The insertion of central venous catheters is, nowadays, a common practice in the field of Anesthesiology. Through this article we present the use of intracavitary ECG guidance as an alternative method to guide the proper placement of the catheter. It is a useful technique, innocuous and easy to carry out. We accompany the text of an explanatory video to facilitate the understanding of the technique.
Driving pressure y mortalidad en el síndrome de distrés respiratorio agudo
Authors: Isabel de la Calle Gil  , Rosalía Navarro Casado  , Raquel García Álvarez
Published: April 2021

Las actuales guías de manejo del síndrome de distrés respiratorio agudo (SDRA) recomiendan una ventilación protectora: volumen corriente bajo, presión positiva al final de la espiración (PEEP) adecuada y maniobras de reclutamiento alveolar. Sin embargo, estudios recientes han mostrado que la driving pressure podría ser la variable que mejor se correlaciona con la supervivencia en pacientes con SDRA. ABSTRACT Driving pressure and mortality in acute respiratory distress syndrome Current guidelines for ventilation in patients with acute respiratory distress syndrome (ARDS) recommend lung-protective ventilation: use of low tidal volumes, appropiate  positive end-expiratory pressure and alveolar recruitment maneuvers. However, recent studies have shown that driving pressure could be the variable that best correlated with survival in patients with ARDS.
Vía aérea difícil imprevista, evitable ¿Qué podemos hacer para mejorar?
Authors: Arritxu Zendoia Martín  , Karlos Reviejo Jaka  , María B. Serna Gandía
Published: April 2021

Antecedente: La predicción de dificultad en la vía aérea constituye el primer paso y la base para establecer las estrategias de seguridad clínica a seguir en su abordaje.  Dentro de los predictores disponibles para el reconocimiento de una vía aérea difícil (VAD),  el antecedente de VAD es uno de los más importantes. Para que ese antecedente de VAD llegue a un futuro episodio es necesario realizar un buen registro y documentación de la dificultad en la vía aérea y además que se activen las vías de transmisión de la información de una VAD de manera eficaz. Método: Para tratar de averiguar la magnitud real del problema de la transmisión crítica de la vía aérea, a nivel nacional, se planteó un estudio tipo encuesta transversal, prospectiva, dirigida a Especialistas de Anestesiología y Reanimación. La encuesta subdivide el problema expuesto en tres apartados: 1.registro estandarizado de la vía aérea, 2.concepto de VAD y 3.documentación de una VAD. En este artículo presentamos los resultados de la encuesta en el apartado de la documentación de una VAD siguiendo como referente las recomendaciones de la ASA de 2013 a ese respecto. ABSTRACT Avoidable, Unanticipated Difficult Airway. We can do something to improve our results? First results of the survey. Background: The prediction of a difficult airway is the first step to establish a clinical safety strategie to follow in its approach. Among predictors available for the recognition of a difficult airway (DA), DA background is one of the most relevant. To prevent future episodes of DA, it´s necessary to record and document previous events, and  also activate effective ways to transmite the DA information. Method A prospective, cross-sectional study was performed, including specialists in anesthesiology and reanimation. It was subdivided into three sections: 1. Standardized airway registration, 2. DA definition, and 3. Documentation of a DA. In this article, we present the results of the DA documentation section following the 2013 ASA Guidelines recommendations.
Monitorización hemodinámica: de la fisiólogia a la monitorización.
Authors: José Llagunes Herrero
Published: April 2021

Resumen Para la comprensión del paciente hemodinámicamente inestable y su tratamiento se requiere un conocimiento de la propia fisiología cardiovascular y los métodos de monitorización hemodinámica disponibles. En esta revisión se debatirá el papel de la circulación sanguínea tanto venosa como arterial y la monitorización del gasto cardiaco, en especial mediante ecocardiografía. La revisión se estructura en los apartados siguientes: la fisiología venosa, la arterial y la monitorización hemodinámica. Es necesario incluir conceptos ya conocidos como la presión media sístemica de llenado (PMS) y la elastancia (E) tanto aortica como dinámica para poder evaluar la respuesta a la administración de fluidos. En un futuro próximo los algoritmos de los monitores hemodinámicos incluirán estas variables y otras muchas que nos proporcionaran una herramienta muy útil para el manejo del paciente hemodinámicamente inestable.  Abstract Hemodynamic monitoring: from physiology to monitoring. For the understanding of the hemodynamically unstable patient and its treatment, a knowledge of the cardiovascular physiology and the available hemodynamic monitoring methods is required. In this review, the role of both venous and arterial blood circulation and cardiac output monitoring, especially by echocardiography, will be discussed. The review is structured in the following sections: venous, arterial and hemodynamic monitoring. It is necessary to include already known concepts such as the average sistemic filling pressure (Psmf) and the elastance (E), both aortic and dynamic, in order to evaluate the response to fluid administration. In the near future the algorithms of the hemodynamic monitors will include these variables and many others that will provide us with a very useful tool for the management of the hemodynamically unstable patient.
Manejo anestésico para craniectomía descompresiva por malformación de Chiari tipo I en paciente con sospecha de síndrome de activación mastocitaria
Authors: Fátima Ortiz Parra  , M González De La Aleja  , Claudia Olea Vielba
Published: April 2021

La mastocitosis es una patología infrecuente a la que, sin embargo, todo anestesiólogo debe saber hacer frente por las repercusiones clínicas que pueden derivarse de un manejo perioperatorio inadecuado.  Sus manifestaciones clínicas se deben a la liberación de gránulos de histamina, prostaglandinas y otras sustancias vasoactivas contenidas en los mastocitos, desencadenada por multitud de factores y fármacos, muchos de los cuales son habitualmente empleados en el acto anestésico.  Presentamos el caso de una paciente con sospecha de síndrome de activación mastocitaria y múltiples alergias documentadas, sometida a craniectomía descompresiva por una malformación de Chiari tipo 1 con siringomielia.   ABSTRACT Anaesthetic management for descompressive craniectomy in Chiari type I malformation in a patient with suspicion of mast cell activation syndrome Mastocytosis is a rare disease whose management must be performed by any anaesthetist because of the clinical consequences that an innapropiate perioperative management may bring.   Its clinical manifestations are due to the release of histamine and other pro-inflammatory substances holded by mast cells, triggered by multiple elements and many drugs: more specifically, many of the drugs we use in the anaesthetic procedure. We present the case of a patient with suspicion of mast cell activation syndrome and many certified allergies, who was proposed to be operated on because of a Chiari type 1 malformation with syringomyelia.
Feocromocitoma: Cirugía urgente vs Cirugía programada
Authors: Paola Navarro Lago  , Aida Fernández García  , Meta Levstek
Published: April 2021

El feocromocitoma es un tumor de células cromafines localizado preferentemente en la cavidad abdominal y en particular en la glándula suprarrenal. Clínicamente puede ser asintomático o presentarse con una amplia variedad de síntomas, dada su capacidad de secretar catecolaminas, tales como hipertensión arterial junto con la triada clásica de cefalea, hiperhidrosis y taquicardia. A continuación, presentamos un caso  clínico de un paciente de sexo masculino, de 24 años, que debuta con pérdida de fuerza en extremidades derechas tras crisis hipertensiva y hematoma en ganglios basales, al cual se tiene que intervenir de urgencia bajo la sospecha de tumor feocromocitoma, con posterior diagnóstico, preparación prequirúrgica meticulosa y cirugía programada del mismo.
Evidencia en fluidoterapia perioperatoria. Un tema aún pendiente.
Authors: Maria A Perez Herrero
Published: April 2021

La fluidoterapia intravenosa constituye uno de los pilares fundamentales en los protocolos y vías clínicas de optimización de recuperación postquirúrgica. En este artículo se revisan las nuevas recomendaciones en base a la evidencia actual: desde la limitación del ayuno preoperatorio y la monitorización hemodinámica del volumen sistólico, pasando por un balance hídrico restrictivo y permisivo en el intraoperatorio y la recuperación rápida de la vía oral en las primeras horas de la intervención. En caso de hipotensión o registro de perfusión tisular deficiente, se debe optimizar la volemia antes de iniciar tratamientos inotrópicos o vasopresores.
Mejorando la seguridad del paciente: los medicamentos en la bandeja de anestesia.
Authors: Mercedes Power Esteban  , María Lema Tomé  , Pilar Cabrerizo Torrente
Published: April 2021

Los errores de medicación en anestesia, siguen siendo una causa grave de daño iatrogénico. Presentamos un estudio en el que se evalúa el potencial impacto de seguridad del uso de una bandeja con códigos de colores para la preparación y el almacenamiento de medicamentos anestésicos. ABSTRACT Improving patient safety: medication in the anaesthesia tray. Medication errors in anesthesia remain a serious cause of iatrogenic damage. We present a study in which the potential safety impact of the use of a tray with color codes for the preparation and storage of anesthetic drugs is evaluated.
¿Disponemos de un protocolo "ideal" en la intubación con fibrobroncoscopio en el paciente con vía aérea difícil anticipada? Revisión
Authors: Natalia Muñoz Ávalos  , Jara Palamidessi Domínguez
Published: April 2021

La intubación con fibrobroncoscopio en el paciente despierto supone una buena opción para aquellos pacientes con vía aérea difícil conocida que se van a someter a una intervención quirúrgica programada, lo cual permite al anestesiólogo responsable idear un plan de acción para evitar un desenlace no deseado. Son muchos los protocolos que se aplican para ello, pero, la mayoría de las veces, obedecen a la experiencia de cada anestesiólogo y a los resultados obtenidos con su aplicación en la práctica asistencial habitual.  Este artículo es la primera revisión sistemática de ensayos clínicos aleatorizados que se centran en este abordaje. Para ello, se seleccionó principalmente información de cuatro áreas de trabajo: premedicación, sedación, anestesia local y uso de dispositivos y técnicas auxiliares que faciliten la intubación en el paciente despierto. La conclusión final a la que llegan los autores de este artículo es la existencia de gran heterogeneidad en lo que a estos aspectos se refiere, sin que ninguno de los protocolos haya demostrado superioridad en seguridad y eficacia.  ABSTRACT  Do we have an "ideal" protocol in the intubation with fibrobronchoscope in the patient with difficult anticipated airway?: A review. Intubation with fibrobronchoscope in the awake patient is a good option form patient with a known difficult airway who are going to undergo a scheduled surgical intervention, which allows the responsable anesthesiologist to devise a plan of action to prevent an unwanted outcome. There are many protocols that are applied for this but most of the time are due to the experience of each anesthesiologist and the results obtained with application in the usual care practice. This article is the first systematic review or randomized clinical trials focusing on this approach. Information was mainly selected from four areas of work: premedication, sedation, local anesthesia and the use of devices and auxiliary techniques to facilitate intubation in the awake patient. The authors find a great heterogeneity as far as these aspects are concerned, without any of the protocols having demonstrated superiority in safety and efficacy.
AT-121, ¿el opioide perfecto?
Authors: María Martín Orejas  , Víctor Martín Mora
Published: April 2021

Los opioides son los analgésicos más potentes y efectivos de que disponemos en la actualidad. Su cara oscura la encarna el creciente aumento de pacientes adictos a su consumo en todo el mundo, principalmente en Estados Unidos. Desde el descubrimiento de los primeros opioides sintéticos, la industria farmacéutica se halla en busca de un analgésico que no genere tolerancia ni dependencia, ni efectos adversos respiratorios. La mayoría de los opiáceos son agonistas del receptor mu, cuya activación aumenta la disponibilidad sináptica de dopamina, neurotransmisor vehicular en circuitos de recompensa. Sin embargo, un cuarto receptor opioide ha sido descrito recientemente: el receptor de nociceptina/orfanina. Su activación inhibe la liberación de dopamina, evitando el refuerzo positivo que ocurre tras el consumo del fármaco. AT-121 es un agonista bifuncional MOP/NOP que ha sido probado en primates no humanos con resultados prometedores en cuanto a potencia analgésica, menores efectos secundarios sistémicos y menor tasa de adicción y abuso. Tales características hacen de esta molécula un arma esperanzadora en el tratamiento del dolor crónico o de la propia adicción a fármacos opioides. En los últimos años se han explorado distintos agonistas bifuncionales en roedores y primates no humanos con interesantes resultados; quedamos pues a la espera de futuras investigaciones en humanos. ABSTRACT Is AT121 the perfect opioid? Opioids are the most powerful and effective analgesics available today. Their dark side is reflected in the growing number of patients addicted to their use around the world, mainly in the United States. Since the discovery of the first synthetic opioids, the pharmaceutical industry has been searching for an analgesic that does not generate tolerance or dependence, nor adverse respiratory effects. Most opioids are mu receptor agonists, whose activation increases the synaptic availability of dopamine, a neurotransmitter that is a carrier in reward circuits. However, a fourth opioid receptor has recently been described: the nociceptin/orphanine receptor. Its activation inhibits the release of dopamine, preventing the positive reinforcement that occurs after drug consumption. AT-121 is a bifunctional MOP/NOP agonist that has been tested in non-human primates with promising results in terms of analgesic potency, fewer systemic side effects, and lower rate of addiction and abuse. Such characteristics make this molecule a hopeful weapon in the treatment of chronic pain or addiction to opioid drugs. In recent years, different bifunctional agonists have been explored in rodents and non-human primates with interesting results; we are therefore awaiting future research in humans.
¿Equivale una mejor visión a una mejor intubación? Artículo original: MazzinariG, Rovira L, Henao L, Ortega J, Casasempere A, Fernandez Y. Effect of Dynamic Versus Stylet-Guided Intubation on First-Attempt Success in Difficult Airways Undergoing Glidescope Laryngoscopy: A Randomized Controlled Trial. Anesthesia-Analgesia. June 2019.Volume 128.Number 6.
Authors: Miguel Angel Fernández Vaquero  , Natalia Garrido Bermudo  , Agustín Martínez Escribano
Published: April 2021

El fracaso de intubación en un paciente con Vía Aérea Difícil (VAD) todavía no es infrecuente, es por ello que la amplia utilización de dispositivos de rescate de la laringoscopia directa sigue en auge. Es en este ámbito donde cobran fuerza los videolaringoscopios, que ofrecen una laringoscopia indirecta a través de un montaje multivariado de lentes y ópticas. Los videolaringoscopios nos han aportado en la especialidad de Anestesiología una visión enormemente nítida en muchos casos de glotis prácticamente imposibles, mejorando por tanto el grado de visibilidad ( clasificado en la Escala de Cormack-Lehane), pero esta ventaja no siempre conduce a un aumento en la tasa de éxito de intubación traqueal, debido a que la adecuada inserción del tubo a través de las cuerdas vocales es un factor limitante. Por ello se precisa de guías que permitan dar al tubo endotraqueal una forma adecuada para una correcta intubación. En este estudio se pretende evaluar la tasa de éxito con un videolaringoscopio usando una guía tradicional preformada con cierto ángulo de movilidad anteroposterior vs guía flexible que permite movilidad anteroposterior y lateral como es un fibrobroncospio con la fibra óptica apagada. Los resultados muestran una mejor tasa éxito en la intubación en el primer intento y menor tasa de complicaciones en el manejo de las vías respiratorias. ABSTRACT  Better vision makes better intubation? The failure of intubation in a patient with Difficult Airway (VAD) is not yet uncommon, which is why the wide use of rescue devices for direct laryngoscopy is still booming. It is in this area where videolaryngoscopy gain strength, offering indirect laryngoscopy through a multivariate assembly of lenses and optics. Videolaryngoscopy have given us in Anesthesiology an enormously clear vision in many cases of practically impossible glottis, thus improving the degree of visibility (classified in the Cormack-Lehane Scale), but this advantage does not always lead to an increase in the success rate of tracheal intubation, due to the proper insertion of the tube through the vocal cords is a limiting factor. Therefore, stylet-guides are required that need to give the endotracheal tube a suitable form for proper intubation. In this study, it is expected to evaluate the success rate with a videolaryngoscope using a traditional preformed stylet-guide with a certain angle of anteroposterior mobility vs. flexible guidance that allows anteroposterior and lateral mobility such as a fiberscope with the optical fiber turned off. The results experienced a better success rate in intubation on the first attempt and a lower rate of complications in airway management with glidescope+fiberscope.
Anestesia intradural en la Enfermedad de Charcot-Marie-Tooth: A propósito de un caso
Authors: Silvia Montero Caballero  , María Loreto Gómez Martínez  , Irene García Sáiz
Published: April 2021

La neuropatía sensitivo-motora hereditaria, también conocida como Enfermedad de Charcot-Marie-Tooth, es una de las enfermedades hereditarias más frecuentes en nuestro país. Engloba un espectro de trastornos causados por mutaciones específicas en genes que codifican la mielina y que ocasionan defectos en su estructura, formación y mantenimiento. Existe escasa evidencia clínica disponible en relación al uso de anestesia regional en pacientes con esta enfermedad, lo que pone de manifiesto la necesidad de documentar los casos en los que se hayan empleado técnicas de anestesia locorregional con el fin de establecer estrategias de actuación.
Un punto débil. Cálculo del NNT en metanálisis.
Authors: Manuel Molina
Published: April 2021

El NNT es una medida absoluta de efecto que se utiliza para estimar la eficacia o seguridad de una intervención. En un principio se ideó para describir el efecto de la intervención respecto al grupo control en los ensayos clínicos, aunque posteriormente se extendió su uso para interpretar los resultados de las revisiones sistemáticas y de los metanálisis. Es en estos casos en los que hay que tener en cuenta la variabilidad de los riesgos de los estudios primarios para obtener una mejor estimación de su valor.
Electroencefalografía clínica para el anestesiólogo
Authors: Rocio López Herrero  , Belén Sánchez Quirós  , David Velasco Villanueva
Published: April 2021

La monitorización electroencefalográfica intraoperatoria de la profundidad anestésica es una práctica habitual en anestesiología. Los sistemas de monitorización no invasivos se fundamentan en un registro electroencefalográfico obtenido por un sensor que se coloca en la frente del paciente. El monitor procesa la señal eléctrica cerebral y refleja mediante un número el grado de inconsciencia. En muchas ocasiones el número que refleja no corresponde con el contexto clínico del paciente. Por este motivo, consideramos que es necesario conocer unos aspectos básicos sobre electroencefalografía.
Determinantes del Gasto Cardiaco en Anestesia y Cuidados Intensivos
Authors: Daniel Paz Martín  , María Sherezade Tovar Doncel
Published: April 2021

El objetivo fundamental del sistema cardiovascular es transportar fuentes de energía desde el intestino e hígado, y oxígeno desde los pulmones, a todos los órganos para su metabolismo. No menos importante, es la retirada de los productos de desecho del metabolismo y su conducción hacia pulmones, riñones e hígado para su excreción. En el presente trabajo se profundiza en los determinantes del gasto cardiaco.
Por tus acciones te juzgarán. Cálculo del tamaño de la muestra en estudios de supervivencia.
Authors: Manuel Molina
Published: April 2021

El cálculo del tamaño muestral estima el número de participantes que serán necesarios para demostrar el efecto considerado como clínicamente importante, si este existe. En el caso de los estudios de supervivencia cobra más importancia el cálculo del número de sucesos que es preciso observar, a partir del cual se calculará el número de participantes necesarios.
¿Es el protocolo Marik eficaz en shock séptico?
Authors: Elena Armelles Bello  , Raquel García Álvarez
Published: April 2021

En los últimos años, se han realizado numerosos intentos para lograr disminuir la mortalidad asociada al shock séptico, tanto desde el punto de vista del diagnóstico precoz como de optimización del tratamiento. Entre las novedades en el tratamiento se incluye el uso de vitamina C y tiamina asociado a hidrocortisona, habiéndose comprobado en varios estudios observacionales la mejoría de la supervivencia y la disminución del uso de vasopresores. Sin embargo, este nuevo ensayo clínico pone en duda el papel de la vitamina C y la tiamina, sin encontrar diferencias significativas entre la monoterapia con hidrocortisona y la combinación de las tres.
Análisis de la dinámica de dos mallines de altura en Vallecitos, Cordón del Plata, Mendoza, Argentina en el periodo 2002-2019
Authors: Pecker Marcosig Ivanna , Trombotto Liaudat Dario
Published: April 2021

El área de estudio se encuentra ubicada en el Cordón del Plata, Cordillera Frontal, Mendoza, Argentina correspondiendo geográficamente entre los meridianos 69 º 19' y 69 º 26' O y los paralelos 32 º 55' y 32 º 59' S. Aquí encontramos alturas máximas de 6000 msnm con presencia de glaciares y manchones de hielo perenne, sin embargo, el ambiente predominante es periglacial con predominancia de glaciares de escombros, protalus ramparts y superficies de soli y gelifluxión. Sumado a ello se pueden encontrar mallines a alturas superiores a 3000 msnm. El objetivo del presente trabajo es analizar la dinámica producida en dos mallines de altura anualmente frecuentados durante el periodo 2002 - 2019 como bioindicadores de cambios a nivel térmico y humedad a fin de conocer los procesos que pueden estar afectando a los mallines en particular y al ambiente en general.  La metodología utilizada se basa en el uso de imágenes de satélite para la clasificación, digitalización de márgenes de las vegas y construcción de índices (NDVI, NWDI), usos de datos meteorológicos del área de estudio e información relevada en campo en sucesivos inventarios de las geoformas presentes.
Compressive and Flexural Strength Property Enhancement for Fibre Reinforced M30, M50 and M80 Grade Concrete Using Foundry Sand (FS) and Crushed Concrete Waste (CCW)
Authors: S R Pruthviraj , C M Ravi Kumar , H M Yajnodbhavi , T Maruthi , S Raghavendra
Published: April 2021

Now days, many research works are carried for all grades of concrete to make the concrete most economical and durable there by adding the supplementary cementitious materials and alternative replacement aggregates. In this research work deals with the experimental investigation of mechanical properties of the M30, M50 and M80 grade concrete by replacing the fine and coarse aggregate by foundry sand and crushed concrete waste respectively. Mix design procedures were followed as per IRC44:2017 guidelines and recommendation. Proper dosage of super plasticizer (SP) was maintained in the concrete to make it better performed. In this present investigation, a Poly Propylene fibre (PPF) of 0.3% by weight of the cement is used. Mechanical properties such as Compressive strength and Flexural Strength were determined by preparing the respective mould sizes for specific test and are cured for 7, 14 and 28 days and result obtained for respective days were tabulated and discussed.
Fertil - infertil kadınların üreme bilgilerinin ve stres düzeylerinin incelenmesi
Authors: ÇAKI Burcu , SOHBET Rabia
Published: April 2021

Amaç: Bu çalışma, fertil - infertil kadınların, fertilite bilgilerini ve stres düzeylerini karşılaştırmak amacıyla tanımlayıcı olarak yapılmıştır.Gereç ve Yöntem: Araştırmanın örneklemini; 223 gebe ve 157 infertil kadın oluşturmuştur. Veriler, bireylerin tanıtıcı özelliklerini ve üreme bilgilerini ölçen anket formu ve Fertilite Sorun Envanteri (FSE) ile toplanmış, SPSS programında değerlendirilmiştir.Bulgular: Araştırmaya katılan kadınların %79,7’sinin adetlerinin düzenli olduğu, %40’nın adet takvimi/günlüğü kullandığı, infertil kadınların ovulasyon bilgi düzeyleri ile fertil kadınların bilgi düzeyleri arasında anlamlı bir farklılık saptanmıştır. Kadınların Global Stres Puanı ile FSE alt boyutları arasında pozitif yönde anlamlı ilişki bulunmuştur.Sonuç: İnfertil kadınlar fertilite bilinci konusunda fertil kadınlardan daha fazla bilgi sahibi olduğu, fertil kadınların stres düzeyinin daha yüksek olduğu ve kadınların stres düzeyleri arttıkça FSE alt boyutu sorunlarının da paralel olarak arttığı görülmektedir.
Comparison of Familial Mediterranean Fever patients by triglyceride/high-density lipoprotein ratio
Authors: AKTAŞ Ahmet , GEDİKLİ Mustafa Asım , SAHİN Ali
Published: April 2021

Aim: In this study, we aimed to show whether there is a relationship between FMF disease and cardiovascular risk by comparing Triglyceride/HDL-Cholesterol ratios between FMF patients and the control group.Materials and Methods: A total of 300 patients, including 150 Familial Mediterranean Fever (FMF) patients and 150 control groups aged 18-65, were included in our study. Triglyceride/HDL-Cholesterol ratios of the patients were compared.Results: Triglyceride/HDL-Cholesterol ratio was statistically significantly higher in the FMF group than the control group (p=0.026).Conclusion: In FMF patients, the Triglyceride/HDL-Cholesterol ratio can be used as an inexpensive, reproducible predictor in showing a cardiac risk.
COVID-19'lu çocuklarda ABO ve Rh kan gruplarının dağılımı ile klinik seyir arasındaki ilişki
Authors: GÜNDÜZ Mehmet , TEMEL Hayrettin
Published: April 2021

Amaç: Bu çalışma, ABO ve Rh kan gruplarının çocuklarda COVID-19 sıklığını ve semptom gelişimini etkileyip etkilemediğini araştırmayı amaçlamaktadır.Gereç ve Yöntem: Çalışmaya SARS-CoV-2 PCR testi pozitif 337 çocuk ve kontrol grubu olarak 1286 sağlıklı çocuk dahil edildi.Bulgular: Rh (+) çocuklarda hasta oranı, Rh (-) çocuklara göre anlamlı derecede yüksekti (p=0,006). Kan grubu A'nın, COVID-19 vakalarında semptom geliştirme için bir risk faktörü olduğu ve riski artırdığı bulunmuştur. Rh (+) kan grubunun COVID-19 için bağımsız bir risk faktörü olduğu ve COVID-19 vakalarının semptomatik olma oranını artırdığı bulunmuştur.Sonuç: Çalışmamızdan elde edilen veriler, Rh pozitifliğinin çocukları hem COVID-19'a hem de COVID-19 durumunda semptomların gelişimine duyarlı hale getirdiğini ve kan grubu A'nın COVID-19 pozitif çocuklarda semptom geliştirme riskini artırdığını göstermektedir.
Does activeness in organization improve English speaking skill? : University students' perspective
Authors: Yusuf Kamal , Mabagits Syahrul
Published: April 2021

The challenging nature of speaking English in connection to organization activeness of university students lead to some issues. The scarcity of research on that area was amongst the rationales behind conducting this present study. This study aimed to investigate students' perception on organization activeness in improving English speaking ability. A phenomenon in the background of this study indicates the significance of organizational activities fot university students and the salient of English in educational context. This study was conducted at State Islamic University of Sunan Ampel Surabaya participated by 30 students of English Education department whom have actively involved the intra or extra campus organization. The instrument used to collect data for this study was a questionnaire that has been tested for its its validity and reliability. The results of the present study revealed that the student generally demonstrated their positive reflections on that the organizational activeness contributes to improving their English speaking ability.
Designing appropriate English learning materials for Nautical Department at Politeknik Ilmu Pelayaran Semarang
Authors: Fatimah F , Dewi Irma Shinta , Purwantini Sri
Published: April 2021

This research  is aimed to find out the target and learning needs of Nautical students at PIP Semarang and designing the appropriate material for Nautical students at PIP Semarang. This is a Research and Development project. The steps of doing this research are (1) need analysis (2) make syllabus (3) designing materials (4) expert consultation (5) try out material (6) evaluation. The subject of this research is the third-semester students of Nautical department at PIP Semarang. The instruments used are questionnaires for need analysis, interview guide and observation sheets. The data were analyzed by using descriptive quantitative and qualitative. The results of the research recommend three  units namely (1) Initial Call (2) Message Marker and (3) On Board Communication Phrases which are developed with communicative approach. The research gives contribution to the teaching and learning English at Nautical Department of Politeknik Ilmu Pelayaran Semarang.
Word formation process of terms in COVID-19 pandemic
Authors: Fitria Tira Nur
Published: April 2021

The objectives of this research are to know the type and examples of the word-formation process of the terms that appear during pandemic Covid-19. This research uses qualitative research. From the result analysis, some types of word-formation processes include borrowing, compounding, blending, acronym, clipping, and multiple processes. In borrowing, for example, the words “Rapid test” and “Swab test”.  In compounding, for example, the words “handsanitizer, lockdown, coronacoma, coronaspeck and self-quarantine”. In blending, for example, the words ‘covid, covidiot, covidient, quarantini, infodemic, quaranteam, coronials, covexit, covidivorce, quaranteen and coroncation”. In clipping, for example, the words ‘sanny” and “iso”. The word “sanny’ comes from “hand sanitizer” and “Iso” comes from “isolation”. In the acronym, for example, the initials WFH (Work from Home), PPE (Personal Protective Equipment), WFO (Work from Office), and PUI (Person Under Investigation). In multiple processes for example the words “handwashing”, zoomboombing, coronababies, self-isolation”.
Teacher’s strategies in survival speaking learning during COVID-19 pandemic
Authors: Puspitasari Dewi , Nofianto Norma , Huda Muhammad Ifanul
Published: April 2021

This paper focuses on the teacher’s strategies during an online learning in Survival Speaking subject. Drawing on narrative inquiry, the paper describes and analyzes how a teacher deals with online learning from August to September 2020. The paper concludes that the teacher experienced challenges in teaching during the pandemic and he was stimulated to provide engaging learning by combining both synchronous and asynchronous mode of learning for his Survival Speaking students. The teaching practice was affected by his teaching philosophy and the implementation was in accordance to Vigotskian’ Zone of Proximal Development in conducting the learning during COVID-19 pandemic by providing help and support for the students before making sure the students would be ready in the real practice.
SURVEI TENTANG KEMAMPUAN MENGGIRING BOLA DALAM PERMAINAN SEPAKBOLA PADA SISWA SMK NEGERI 1 MANADO
Authors: Rompas Maisje Afrida
Published: April 2021

Penelitian ini bertujuan untuk mengetahui: Survei Tentang Kemampuan Menggirirng Bola dalam Permainan Sepakbola Pada Siswa SMK Negeri 1 Manado. Populasi dalam penelitian ini adalah siswa putra kelas XI yang berjumlah 15 orang, sehingga penelitian dilakukan pada populasi. Mengacu pada deskripsi data dengan hasil perhitungan yang diperoleh 33,33% (5 responden) memiliki skor rata-rata, 20% (3 responden) memiliki skor dibawah rata-rata, dan 46,67% (7 responden) memiliki skor diatas rata-rata. Ini berarti bahwa siswa SMK Negeri 1 Manado memiliki kemampuan menggiring bola dalam permainan sepak bola yang baik yang diperoleh 46,67% (7 responden) memiliki skor diatas rata-rata, sedangkan 33,33% (5 responden) memiliki skor rata-rata dan 20% (3 responden) memiliki skor dibawah rata-rata.
HUBUNGAN FEMALE ATHLETE TRIAD DENGAN PERUBAHAN SIKLUS MENSTRUASI DI PPLP PROVINSI MALUKU
Authors: Pieter Marsiline
Published: April 2021

Menstruation is derived from uterine bleeding as a sign that the tool implies fulfill its function, which happens every month regularly on a grown woman whois healthy and not pregnant. Female athlete triad is a combination of three interrelated conditions that are deviant behavior of food, menstrual disorder and osteoporosis. Purpose; to determine the relationship of the female athlete triad with menstrual cycle changes in PPLP Maluku Province. This research using cross sectional approach. The sampling technique  is total sampling. Samples in this study were female athlete PPLP Maluku Province totaling 38 people. Data collection technique such as statistical test questioner using Chi-square with signification level (<0.05). The results showed that the relationship amenorrhea with menstrual cycle changes with the value of P = 0,001. Relations irregularities eating behavior with changes in the menstrual cycle with P= 0,010. Osteoporosis relations with changes in the menstrual cycle with P= 0,477 where (p <0.05). Conclusion; relationship amenorrhea, behavioral deviations eating menstrual cycle changes in PPLP Maluku Province. It is expected that youth advice agencies and olahraga, can give attention to the development and health of the athletes and the coaches to organize and  prepare training schedule female athletes and improve insight not only improve performance in the championship but in knowledge about reproductive health.
SURVEY TENTANG PERBANDINGAN HASIL SHOOT DENGAN MENGGUNAKAN TEKNIK SET SHOOT DAN JUMP SHOOT DALAM PERMAINAN BOLA BASKET PADA TIM PUTRI PROGRAM STUDI PENDIDIKAN OLAHRAGA UNIVERSITAS NEGERI MANADO
Authors: Lomboan Ellen B.
Published: April 2021

Penelitian ini bertujuan untuk mengetahui: Efektivitas teknik set-shoot dan jump-shoot dalam suatu pertandingan masih merupakan fenomena, karena banyak anggapan berbeda yang muncul. Satu pihak menyatakan set-shoot lebih efektif dan pihak yang lain menyatakan jump-shoot lebih efektif. Oleh karena itu perlu dilakukan penelitian mengenai analisis hasil set-shoot dengan teknik jump-shoot dalam pertandingan bola basket. Mengumpulkan data dari sampel penelitian diperlukan alat yang disebut instrumen. Dalam penelitian ini, peneliti melakukan observasi dan dokumentasi. Hasil perhitungan yang terlihat1 dapat dijelaskan bahwa pengunaan jump shoot atlet bola basket putri Program Studi Pendidikan Olahraga Universitas Negeri Manado 40 % (4 sampel) berada pada skor rata-rata, 20% (1 sampel) berada pada skor dibawah. Hasil perhitungan yang terlihat pada dapat dijelaskan bahwa pengunaan jump shoot atlet bola basket putri Program Studi Pendidikan Olahraga Universitas Negeri Manado 60 % (3 sampel) berada pada skor rata-rata, 20% (2 sampel).
Utilização de Estruturas de Aço para o Projeto e Construção Sustentável da Plataforma Skyglass Canela
Authors:   Universidade do Estado do Rio de Janeiro,, Santos da Silva J. G. , Debona G. L. ,   Universidade Federal Rural do Rio de Janeir
Published: April 2021

Conhecido internacionalmente por possuir um clima tropical, com belas praias e cenários paradisíacos, o Brasil é uma das referências em turismo nesta área, principalmente tendo em mente a região nordeste. Entretanto, o sul brasileiro também representa um excelente destino para quem procura conforto, cultura e, claro, uma temperatura mais agradável. Neste quesito, o estado do Rio Grande do Sul/RS se destaca por possuir a “serra gaúcha”, região serrana do estado, sendo um dos destinos mais procurados e visitados no Brasil, atraindo milhões de pessoas por ano devido ao seu clima, pontos turísticos e culinários [1]. As cidades de Gramado/RS e Canela/RS, localizadas na “serra gaúcha”, representam os pontos turísticos mais famosos e cobiçados da região sul do Brasil, apresentando as quatro estações do ano de maneira bem definida, com invernos mais intensos, podendo inclusive nevar, e verões com temperaturas mais amenas, alcançando até os 25ºC, e favorecendo os passeios ao ar livre [1]. A cidade de Gramado/RS, localizada a 120 km de Porto Alegre, capital do Rio Grande do Sul/RS, é conhecida pelo turismo no interior de museus, casas de founde, além do tradicional “Natal Luz de Gramado”, iniciado em 1986 e contando com mais de 500 atrações [1] [2]. De outra forma, Canela/ RS, cidade vizinha distante apenas sete quilômetros de Gramado é bastante conhecida pelos passeios ao ar livre, valorizados pela natureza exuberante, e por sua gastronomia. O principal cartão postal da cidade é a Cascata do Caracol com uma queda d’água de 131 metros, localizada no Parque Estadual do Caracol em uma área preservada de 25 hectares (Figura 1) [2]. Neste contexto, a partir de 17 de dezembro de 2020, o município de Canela ganhou um novo concorrente para o principal ponto turístico da cidade, correspondente a uma plataforma estaiada de aço e vidro, denominada comumente de Skyglass (Figura 2) [3].
Documentos de inspeção para os produtos constituintes no âmbito da EN 1090
Authors:   Associação para o Desenvolvimento da Engenharia Civil – ACIV, Gonçalves Sérgio
Published: April 2021

Neste artigo aborda-se a importância dos documentos de inspeção, usualmente designados por certificados de material, para a rastreabilidade dos produtos, os vários tipos de documentos de inspeção e as diferenças entre eles. Por último, apresentam-se os documentos de inspeção a serem fornecidos com os produtos constituintes integrados nas estruturas e componentes do âmbito das atuais normas EN 1090 partes 2, 3, 4 e 5.
Subchronic Toxicity of Crinum jagus Extracts on Wistar Rats
Authors: Clemence Mvongo , Rene Kamgang , Jean-Louis Essame Oyono
Published: April 2021

Crinum jagus is used in Cameroon western and eastern regions folk medicine in detoxification, the management of diabetes and obesity and also as antivenomous and antipoison. The aim of this work was to evaluate the subchronic toxicity of Crinum jagus extracts on male and female Wistar rats. Subchronic toxicity of aqueous and hydroéthanolic Crinum jagus extracts was determined on two month old normal Wistar rats. Those rats, once daily orally received, hydroethanolic (75, 150 mg/kg b.w.) and aqueous (150 mg/kg b.w.) extracts, during 90 days (tree month). In both males and females animals, the C. jagus effects were investigated on the evolution of weight, food and water intakes, kidney and liver functioning markers (serum total cholesterol (TC), total proteins, creatinine and transaminase: AST and ALT). Both aqueous and hydroethanolic extracts in males as in females, did not cause any adverse changes in anthropometric (body mass, relative weight of liver and kidneys, food and water intakes) and seric parameters (total cholesterol, total proteins, creatinine AST and ALT activity). Instead, those extracts remarkably improved antropometric parameters, liver and kidney function and even protect again atherosclerosis. The results indicated that aqueous and hydroethanolic extracts of Crinum jagus did not induce toxic effect at the doses used in long term treatment; thus justifying its empiric use in detoxification and as antivenomous.
A Escola Austríaca no pensamento de Donald Stewart Jr.
Authors: Berlanza Corrêa Lucas
Published: April 2021

O presente artigo se destina a sintetizar a influência das ideias e matrizes da Escola Austríaca de Economia no pensamento do empresário e ativista brasileiro Donald Stewart Jr., oferecendo um panorama do significado de sua atuação para difundir essa linha de pensamento no país. Partindo de uma breve abordagem da posição historicamente ocupada por ele como introdutor de uma literatura correlata e como fundador do Instituto Liberal, em 1983, o trabalho procurará conectar esse esforço à atual popularidade dos autores austríacos no país, mostrando como o empresário e a instituição por ele fundados foram determinantes para isso, e expor as visões de Stewart, especialmente a partir de sua obra O Que é o Liberalismo, acerca da contribuição que essa corrente intelectual poderia oferecer aos problemas da realidade brasileira.
Catolicismo Romano e a Livre Iniciativa
Authors: Roberto da Silva Andrei
Published: April 2021

Resenha do Livro:
WOODS JR, Thomas E. A Igreja e o Mercado: Uma defesa Católica da economia de livre mercado. Campinas: Vide Editorial, 2019. 352p.
Factors that influence learners’ decisions to drop out of subjects at the Namibian College of Open Learning (NAMCOL): Distance learning mode
Authors:   Namibian College of Open Learning (NAMCOL), Namibia, Nampila Tutaleni
Published: April 2021

The Namibian College of Open Learning (NAMCOL) conducted a dropout survey in order to determine why distance students studying with the College, drop out of the subjects they enrolled for. Information was collected from learners who dropped out of subjects they enrolled for, tutors and Head of Centres. Online and telephonic interviews were used for learners, while questionnaires in hard copies were distributed to the tutors and Head of Centres. The majority of the learners who responded to the questionnaire indicated that the learner support from the College was good and that the study materials were useful. Even so, most learners indicated that job commitments, financial issues and sickness were the main reasons why they dropped out of the subjects they enrolled for. The subject that had the highest dropout rate for both grade 10 and 12, were English. Other reasons given by tutors and head of centres as to why they think learners drop out of subjects include lack of motivation from learners, lack of competency in English and some learners find employment or register at private institutions, centres are far from the learners. Some of the recommendations given by tutors and head of centres to reduce dropouts the College should decentralise the centres, clear, persistent and continuous information regarding examination dates, collecting timetables and venues should be given.
The importance of prebiotics in the regulation of metabolic syndrome disorders
Authors: Nyankovska O. S. , Nyankovskyy S. L. , Yatsula M. S. , Horodylovska M. I.
Published: April 2021

The products of functional foods differ from other meals by their ability to improve health and well‑being or to reduce the risk of diseases and not only to provide the good nutrition. The composition of such products includes oligosaccharides of the fructan type such as inulin. Inulin is a soluble dietary fiber, consisting of a group of natural polysaccharides that are not digested in the intestine and instead fermented into short‑chain fatty acids associated with multiple metabolic processes, including glucose homeostasis and insulin resistance. Besides, inulin affects the lipid exchange regulation and improvement of lipid profile. Inulin is a mixture of linear fructose polymers or fructans with 2 — 60 units, each of them is connected by unique β (2‑1) bonds with a glucose unit. In contrary to typical carbohydrate, these β (2‑1) connections cannot be hydrolyzed by enzymes of saliva or pancreas, that’s why inulin has a reduced energetic value as well as dietary prebiotic effects.Functional food is an important component of the change in the lifestyle to control obesity and related risks for health. Obesity and dyslipidemia are important aspects of metabolic syndrome, associated with changes in the gut microbiome. The most important direction in the modern preventive and therapeutic medicine presents the use of prebiotics, that provide positive effects on the normal microflora and cause a whole cascade of secondary beneficial effects for humans (metabolic, anticarcinogenic, immunostimulating, antitoxic, etc.). Prebiotic Inulin promotes the restoration of intestinal microbiome by means of increasing production of intestinal epithelial cells and recovering interleukin‑22 expression.On the domestic market inulin presented as an Inulin‑NEO preparation, available in a form of tablets and sachet, which makes it easy to use.
Pengaruh Metode Pembelajaran dan Motivasi Belajar Siswa terhadap Hasil Belajar Bahasa Indonesia
Authors: Suratmi Dasti
Published: April 2021

Tujuan penelitian ini adalah untuk mengetahui pengaruh metode pembelajaran dan motivasi belajar terhadap hasil belajarbahasa Indonesia. Model penelitian yang digunakan adalah Eksperimen. Sampel penelitian terdiri dari 80 siswa yang terbagi atas 40 siswa kelas eksperimen dan 40 siswa kelas kontrol, dengan teknik cluster sampling. Instrumen penelitian yang digunakan yaitu tes preferensial yang telah diuji validitasnya dengan koefisien reliabilitas >0,70. Analisis data menggunakan ANOVA dua jalur. Hasil penelitian menunjukkan: (1) Terdapat pengaruh yang signifikan metode pembelajaran terhadap prestasi belajar bahasa Indonesia siswa SMP N Kecamatan Babelan. Hal tersebut dibuktikan dengan nilai Sig = 0,000 < 0,05. dan Fhitung = 29,684. (2) Terdapat pengaruh yang signifikan antara motivasi belajar terhadap hasil belajar bahasa Indonesia siswa SMPN Kecamatan Babelan. Hal tersebut dibuktikan dengan nilai Sig = 0,007 < 0,05 dan Fhitung = 7,553. (3) Terdapat pengaruh interaktif yang tidak signifikan antara metode pembelajaran dan motivasi belajar terhadap hasil belajar bahasa Indonesia siswa SMPN Kecamatan Babelan. Hal tersebut dibuktikan dengan nilai Sig = 0,315 > 0,05 dan nilai Fhitung = 1,025. Hasil penelitian ini berguna untuk peningkatan kemampuan hasil belajar bahasa Indonesia pada siswa dengan memperhatikan metode pembelajaran dan motivasi belajar yang dimilikinya dalam kelas. Kata kunci: Metode Pembelajaran, Motivasi Belajar, Hasil Belajar Bahasa Indonesia