bluuebunny/crossref_metadata_2025 huggingface dataset:
Oxygen-Based Autoregulation Indices Associated with Clinical Outcomes and Spreading Depolarization in Aneurysmal Subarachnoid Hemorrhage
Authors: Carlson Andrew P. , Jones Thomas , Zhu Yiliang , Desai Masoom , Alsarah Ali , Shuttleworth C. William
Published: August 2024

Background

Impairment in cerebral autoregulation has been proposed as a potentially targetable factor in patients with aneurysmal subarachnoid hemorrhage (aSAH); however, there are different continuous measures that can be used to calculate the state of autoregulation. In addition, it has previously been proposed that there may be an association of impaired autoregulation with the occurrence of spreading depolarization (SD) events.

Methods

Study participants with invasive multimodal monitoring and aSAH were enrolled in an observational study. Autoregulation indices were prospectively calculated from this database as a 10 s moving correlation coefficient between various cerebral blood flow (CBF) surrogates and mean arterial pressure (MAP). In study participants with subdural electrocorticography (ECoG) monitoring, SD was also scored. Associations between clinical outcomes using the modified Rankin scale and occurrence of either isolated or clustered SD were assessed.

Results

A total of 320 study participants were included, 47 of whom also had ECoG SD monitoring. As expected, baseline severity factors, such as modified Fisher scale score and World Federation of Neurosurgical Societies scale grade, were strongly associated with the clinical outcome. SD probability was related to blood pressure in a triphasic pattern, with a linear increase in probability below MAP of ~ 100 mm Hg. Multiple autoregulation indices were available for review based on moving correlations between mean arterial pressure (MAP) and various surrogates of cerebral blood flow (CBF). We calculated the pressure reactivity (PRx) using two different sources for intracranial pressure (ICP). We calculated the oxygen reactivity (ORx) using the partial pressure of brain tissue oxygen (PbtO2) from the Licox probe. We calculated the cerebral blood flow reactivity (CBFRx) using perfusion measurements from the Bowman perfusion probe. Finally, we calculated the cerebral oxygen saturation reactivity (OSRx) using regional cerebral oxygen saturation measured by near-infrared spectroscopy from the INVOS sensors. Only worse ORx and OSRx were associated with worse clinical outcomes. Both ORx and OSRx also were found to increase in the hour prior to SD for both sporadic and clustered SD.

Conclusions

Impairment in autoregulation in aSAH is associated with worse clinical outcomes and occurrence of SD when using ORx and OSRx. Impaired autoregulation precedes SD occurrence. Targeting the optimal MAP or cerebral perfusion pressure in patients with aSAH should use ORx and/or OSRx as the input function rather than intracranial pressure.
Dynamics Behaviours of Kink Solitons in Conformable Kolmogorov–Petrovskii–Piskunov Equation
Authors: Ullah Ikram , Shah Kamal , Abdeljawad Thabet , Alam Mohammad Mahtab , Hendy Ahmed S. , Barak Shoaib
Published: August 2024

The current study introduces the generalised New Extended Direct Algebraic Method (gNEDAM) for producing and examining propagation of kink soliton solutions within the framework of the Conformable Kolmogorov–Petrovskii–Piskunov Equation (CKPPE), which entails conformable fractional derivatives into account. The primary justification around employing conformable derivatives in this study is their special ability to comply with the chain rule, allowing for in the solution of aimed nonlinear model. The CKPPE is a crucial model for a number of disciplines, such as mathematical biology, reaction-diffusion mechanisms, and population increase. CKPPE is transformed into a Nonlinear Ordinary Differential Equation by the proposed gNEDAM, and many kink soliton solutions are found by applying the series form solution. These kink soliton solutions shed light on propagation mechanisms within the framework of the CKPPE model. Furthermore, our research offers multiple graphical depictions that facilitate the examination and analysis of the propagation patterns of the identified kink soliton solutions. Through the integration of mathematical biology and reaction-diffusion principles, our research broadens our comprehension of intricate occurrences in various academic domains.
The game management framework for sports refereeing: a structured perspective on officiating performance and its development
Authors: Hoffmann Theresa , MacMahon Clare , Brand Ralf
Published: August 2024

The Game Management Framework for Sports Refereeing (GMFSR) provides a comprehensive and novel approach to understanding the performance of on-field interactor referees in competitive sports. It highlights key performance factors and focuses on the holistic integration of essential elements. According to the GMFSR, officiating performance is based on a referee’s embodied concepts: rules, laws and regulations and game knowledge; contextual judgment; physical fitness, positioning, and signaling; and dynamic communication and arbitration. These elements underpin the four skills of administering the game, decision-making, creating presence, and guiding the game, which together make up a referee’s game management competency. In addition, the framework emphasizes the importance of a referee mindset, stressing the influence of personal attributes and adaptive strategies on overall performance. Developed by integrating empirical evidence, different conceptual and theoretical perspectives, and expert knowledge from academia and practice, the GMFSR aims to provide a comprehensive foundation on which to stimulate ideas for the education and training of referees. It is hoped that by considering all elements of the GMFSR at the novice level and developing them throughout a referee’s career, it will provide holistic yet focused training, and serve as a valuable resource for future research.
Normen beim Argumentieren mit Darstellungen – Analyse orientierender Referenzkontexte
Authors: Söbbeke Elke
Published: August 2024

Normen spielen beim Argumentieren mit Darstellungen eine zentrale Rolle. Ein Anliegen der interpretativen mathematikdidaktischen Forschung ist es, die interaktive Aushandlung fachspezifischer Normen aus Sicht der Lernenden zu rekonstruieren. Um diese komplexen Aushandlungsprozesse zwischen verschiedenen Beteiligten untersuchen zu können, bedarf es zunächst eines besseren Verstehens auf der Mikroebene. Der vorliegende Artikel adressiert dieses Forschungsdesiderat exemplarisch für das Argumentieren von Grundschulkindern mit Punktdarstellungen im Kontext von Parität. Zur theoretischen und empirisch basierten Klärung verknüpft der Beitrag zwei verschiedenen Perspektiven des Forschungsfeldes: Eine fachspezifisch-theoretische Perspektive und eine fachspezifisch-empirisch-interaktionistische Perspektive auf Normen. Die Analyse der empirischen Fallstudien zeichnet die situativ orientierenden Bezugnahmen in den Argumentationen der Kinder nach und reflektiert Bezüge zu grundlegenden fachspezifisch-theoretischen Normen.
The Impact of Hesperidin on Cognitive Deficit and Neurobehavioural Disorders: A Systematic Review and Meta-Analysis of Preclinical Individual Studies
Authors: Olasehinde Tosin A. , Ekundayo Temitope C. , Ijabadeniyi Oluwatosin A. , Olaniran Ademola O.
Published: August 2024

Purpose of Review Experimental evidence suggests that flavonoids prevent neurodegeneration and improves cognitive function. In this study, we systematically reviewed the effect of hesperidin on cognitive deficits and neurobehavioural outcomes in in vivo studies.

Recent Findings: A systematic search of PubMed, EBSCOhost, Web of Science, Scopus and ProQuest was conducted. Meta-analysis was performed on the effect of hesperidin on cognitive and neurobehavioural parameters (Morris Water Maze, Y-Maze, elevated plus maze, rotarod test, locomotion activity, passive avoidance test, open field test and forced swimming test). The mixed effect model was used to compute the standard mean difference (SMD). A total of 1069 documents were retrieved. However, 46 studies were included in the systematic review and meta-analysis. Our findings revealed that hesperidin did not significantly affect cognitive performance in normal rats compared with placebo. Moreover, hesperidin improved memory and learning, sensorimotor function and locomotion activity in cognitive impaired rats. Hesperidin did not show any significant effect on anxiety-related outcomes in the diseased model.

Summary: Hesperidin improved cognitive function and neurocognitive effects could be associated with its neuroprotective effects against neuroinflammation, oxidative stress-induced neuronal damage, inhibition of cholinergic deficit and mitochondrial dysfunction. These results correlate with available scientific evidence on the effect of hesperidin on cognitive dysfunction and neurobehavioural deficits in cognitive-impaired rats.
Highly Sensitive Ammonia Gas Sensors at Room Temperature Based on the Catalytic Mechanism of N, C Coordinated Ni Single-Atom Active Center
Authors: Quan Wenjing , Shi Jia , Zeng Min , Lv Wen , Chen Xiyu , Fan Chao , Zhang Yongwei , Liu Zhou , Huang Xiaolu , Yang Jianhua , Hu Nantao , Wang Tao , Yang Zhi
Published: August 2024

Significant challenges are posed by the limitations of gas sensing mechanisms for trace-level detection of ammonia (NH3). In this study, we propose to exploit single-atom catalytic activation and targeted adsorption properties to achieve highly sensitive and selective NH3 gas detection. Specifically, Ni single-atom active sites based on N, C coordination (Ni–N–C) were interfacially confined on the surface of two-dimensional (2D) MXene nanosheets (Ni–N–C/Ti3C2Tx), and a fully flexible gas sensor (MNPE–Ni–N–C/Ti3C2Tx) was integrated. The sensor demonstrates a remarkable response value to 5 ppm NH3 (27.3%), excellent selectivity for NH3, and a low theoretical detection limit of 12.1 ppb. Simulation analysis by density functional calculation reveals that the Ni single-atom center with N, C coordination exhibits specific targeted adsorption properties for NH3. Additionally, its catalytic activation effect effectively reduces the Gibbs free energy of the sensing elemental reaction, while its electronic structure promotes the spill-over effect of reactive oxygen species at the gas–solid interface. The sensor has a dual-channel sensing mechanism of both chemical and electronic sensitization, which facilitates efficient electron transfer to the 2D MXene conductive network, resulting in the formation of the NH3 gas molecule sensing signal. Furthermore, the passivation of MXene edge defects by a conjugated hydrogen bond network enhances the long-term stability of MXene-based electrodes under high humidity conditions. This work achieves highly sensitive room-temperature NH3 gas detection based on the catalytic mechanism of Ni single-atom active center with N, C coordination, which provides a novel gas sensing mechanism for room-temperature trace gas detection research.
Traffic Noise Affects Brazilian Mundo Novo Treefrog Calling Behavior
Authors: Antunes Rógger L. T. , Borges-Martins Márcio , Guagliumi Giorgia , Zaffaroni-Caorsi Valentina
Published: August 2024

Anthropogenic disturbance, including noise, is a major cause of biodiversity decline worldwide. Especially in anurans, the effect of noise pollution is known to have major consequences on their reproduction since acoustic communication is an essential part of this process. In this study, we tested the effect of three levels of traffic noise (55 dB, 65 dB, and 75 dB) corresponding to three different distances from the road (200, 100, and 50 m, respectively) on the Brazilian Mundo Novo treefrog (Boana marginata). The results of the playback experiments showed an effect on call type B. More specifically, there was a decrease in the advertisement call rate, a reduction in the number of pulses, and a lengthening of the interval between pulses, particularly at 65 dB. These findings suggest that at distances of up to 100 m, the masking effect significantly influences acoustic communication on the species. However, a 55 dB stimulus—equal to 200 m from the road edge—did not change the call in this species, suggesting a minimal distance to implement noise-inflicting infrastructures. We recommend that new studies adopt sampling methods from this distance to refine the threshold of the traffic noise effect.
Surface roughness reduction in electron beam powder bed fusion additive manufacturing of super duplex stainless steel 2507: investigating optimisation techniques and face orientation-dependent irregularities
Authors: Roos Stefan , Rännar Lars-Erik
Published: August 2024

The use of additive manufacturing in metals by powder bed fusion via electron beam (PBF-EB) is increasing for fabricating high-quality parts meeting industrial standards. However, high surface roughness poses a consistent challenge in PBF-EB. This study investigates two novel approaches to optimise surface roughness for a given machine and powder combination. Using machine control software’s recently introduced research mode functionality, we develop customised beam control code to effectively explore a vast parameter space. Additionally, we explored the impact of beam travel direction and spot morphology on surface roughness. Line-melt-based contours were explored by specimen manufacturing with layer-wise parameter change, whilst spot-melting-based samples were built using a full factorial design of experiments with four factors at three levels. Initial sample characterisation was done using a stylus-based contact profilometer, followed by detailed evaluation using focus variation microscopy. Results reveal that increasing beam power and spot energy exacerbate surface roughness. We also find that a well-defined energy distribution at the spot's edge contributes to smoother surfaces. Whilst the influence of beam travel direction on surface roughness remains uncertain, our findings underscore the importance of parameter selection in achieving optimal results. By adjusting contouring parameters, we achieve a vertical roughness of Ra17.7 ± 0.9 (Sa 21.6), significantly lower than in the current literature. These findings advance our understanding of surface roughness optimisation in PBF-EB and offer practical insights for improving part quality in industrial applications. By harnessing tailored beam control strategies, manufacturers can enhance the capabilities of additive manufacturing technologies in producing metal components.
Blind Game: An Interactive Installation About How We Can Exorcise Memories of a Visual Disability
Authors: Gouveia Patrícia , Lima Luciana
Published: August 2024

In this paper, we recover an interactive artwork developed by one of the authors to provide possible ways of inserting the playful and artistic perspective into augmented human studies. In this way, a perspective based on play and interactive digital fiction can inspire us to look at other ways of using digital technologies that focus on improving human capabilities. The interactive installation Blind Game brings us a personal, visual, and playful perspective of a person who, at the age of three years, was diagnosed with amblyopia, revealing the subjective world of the character P.. Created in 2001, this installation was an interactive conceptual artwork developed by a young artist who wanted to exorcise the memories of her diagnosis of amblyopia and the tensions caused by the political instability in her home country. Through interaction and playful strategies, the artist sought to abstract herself from the reality around her, reorganizing her subjective relationship with visual impairment and the political tensions of a transition period between a dictatorial government and a democratic one.
On the Impact of Input Models on the Fault Detection Capabilities of Combinatorial Testing
Authors: Baumann Carmen , Koroglu Yavuz , Wotawa Franz
Published: August 2024

Testing is an important activity to detect faults before software deployment. We focus on black-box combinatorial testing, where fault detection is one of the main objectives. In this paper, we argue that input model abstraction notably impacts the fault detection capability of a combinatorial test suite. First, we present experiments from previous work that support this argument. We then perform new experiments on a more diverse set of programs. These experiments use mutation testing to estimate fault detection capability, but we also include structural coverage measures in the new experiments. Finally, we elaborate on two possible improvements to obtain an optimal input abstraction strategy for not just continuous but all input domains. Both experiments suggest that input abstraction affects the fault detection capability. We claim that the improvements will produce a better input abstraction with which we can achieve better fault detection capability without increasing the test suite size.
Modeling the Progression of Haematocrit Level over Time
Authors: Teklezgi Mehari Gebre , Asres Abebech Abera , Matope Agnes , Dabale Gutu Adugna
Published: August 2024

Haematocrit Levels is defined as the proportion, by volume, of the blood that consists of red blood cells. This study was conducted to model the progress of haematocrit levels over time in kidney patients after their transplant and to determine how the progress depends on the age and gender of the patient and other factors. This is a longitudinal study, and haematocrit level was considered as a response while the covariates were time, gender, age, cardio-vascular problem during the years preceding the transplantation, and rejection symptoms during the first three months after the transplantation took place of the patients. Different statistical methods such as, multivariate regression model, two stage analysis and linear mixed effects model were employed to explore the progress of haematocrit over time. Models revealed that haematocrit levels in kidney transplant patients evolve over time. Gender and Age of the patient have significant effect on the evolution of haematocrit levels. Males tend to have a high increase in haematocrit levels over time than females. With regards to age, haematocrit levels tend to increase with increasing age. Moreover, it was observed that experience of cardio-vascular problems before trandplant and rejection symptoms did not have a significant effect on the progress of haematicrit levels. The growth of Haematocrit levels evolve over time follows a quartic time effect. Change in haematocrit levels varies according to gender and age of the patient. Patients starting with low haematocrit levels tend to have a larger increase over time.
Superconductivity and topological quantum states in two-dimensional moiré superlattices
Authors: Zheng Chuanqi , Liu Xiaoxue
Published: August 2024

Moiré superlattices have emerged as an excellent platform for investigating a plethora of exotic quantum states in condensed matter physics. Recent advancements have unveiled abundant discoveries in two-dimensional moiré superlattices. In this paper, we will present a review of the recent progresses in superconductivity and topological physics within graphene and transition metal dichalcogenides-based moiré superlattices. Additionally, we outline future potential challenges and desirable efforts for discovering, understanding, and controlling these novel states in two-dimensional moiré superlattices.
The role of fat in pancreatic diseases: from pathology to imaging
Authors: Raitano Elisabetta , Cannella Roberto , Messana Domenico , Matteini Francesco , Brancatelli Giuseppe
Published: August 2024

Pancreatic fat deposition is frequently evaluated in imaging of pancreatic diseases. This condition can be linked to a broad range of diffuse diseases and focal pancreatic lesions. Abnormal pancreatic and peripancreatic fat is observed in many pathologic conditions, including obesity, diabetes mellitus, cystic fibrosis, acute and chronic pancreatitis, pancreatic lipoma, and teratoma. Pancreatic fat deposition has also been reported to be a risk factor for pancreatic ductal adenocarcinoma and postoperative pancreatic fistula. Pancreatic fat deposition can cause anatomical changes and abnormal secretion function, leading to insulin resistance and high blood glucose levels. The assessment of pancreatic fat deposition can be performed with ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI). MRI is the most accurate method for the quantification of fat using the proton-density fat fraction (PDFF). The aim of this article is to describe the pathological conditions associated with abnormal pancreatic fat. Knowledge of pancreatic fat distribution can help the radiologists in the differential diagnosis of pancreatic diseases.
Long-term meteorological characteristics and extreme climate indices over Tirupati: a rapidly developing tropical city
Authors: Thandlam Venugopal , Kaagita Venkatramana , Sakirevupalli Venkatramana Reddy
Published: August 2024

Tirupati’s climate has undergone significant changes in both temperature and precipitation patterns. While there has been a consistent increase in rainfall during the southwest monsoon, there is a concerning long-term trend of a decrease in total annual precipitation over the last 30 years. The city has experienced a rise in wet days during both the southwest and northeast monsoons, yet a recent decrease over the past three decades. Heavy precipitation events, particularly during the southwest monsoon, have shown a positive trend, whereas there have been no significant changes in heavy rainfall days during the northeast monsoon. Temperature trends reveal that there has been a warming scenario, with a significant positive trend in annual maximum temperatures and a consistent annual rise in mean minimum temperatures. A substantial decrease in cold and very cold days, especially during the last 30 years, suggests a broader warming trend impacting seasonal temperature variations in Tirupati. These findings highlight the complex interplay of monsoons, temperature variations, and changing precipitation patterns in Tirupati's climate over the years.
Virtual laboratories: transforming research with AI
Authors: Klami Arto , Damoulas Theo , Engkvist Ola , Rinke Patrick , Kaski Samuel
Published: August 2024

New scientific knowledge is needed more urgently than ever, to address global challenges such as climate change, sustainability, health, and societal well-being. Could artificial intelligence (AI) accelerate science to meet these global challenges in time? AI is already revolutionizing individual scientific disciplines, but we argue here that it could be more holistic and encompassing. We introduce the concept of virtual laboratories as a new perspective on scientific knowledge generation and a means to incentivize new AI research and development. Despite the often perceived domain-specific research practices and inherent tacit knowledge, we argue that many elements of the research process recur across scientific domains and that even common software platforms for serving different domains may be possible. We outline how virtual laboratories will make it easier for AI researchers to contribute to a broad range of scientific domains, and highlight the mutual benefits virtual laboratories offer to both AI and domain scientists.
Asset-manager society and international financial subordination
Authors: Bonizzi Bruno , Kaltenbrunner Annina
Published: August 2024

This essay critically engages with the concept of asset-manager society (AMS) proposed by Brett Christophers. We begin by drawing out its five key elements through a contrast with the related but distinct concept of asset-manager capitalism. We then ask to what extent AMS can be observed in the countries of the Global South, which are characterised by a subordinate position in international money and financial markets. We conclude by highlighting some potential implications of the rise of AMS in these economies and offering some broader thoughts on the future.
Non-local gravity wave turbulence in presence of condensate
Authors: Korotkevich Alexander O. , Nazarenko Sergey V. , Pan Yulin , Shatah Jalal
Published: August 2024

The

$k^{-23/6}$

wave action spectrum with an inverse cascade is one of the fundamental Kolmogorov–Zakharov solutions for gravity wave turbulence, which is part of the citation for the Dirac Medal in 2003. Instead of confirming this solution, however, several existing simulations and experiments suggest a spectrum of

$k^{-3}$

in set-ups corresponding to the inverse cascade. We provide a theoretical explanation for the latter, considering the condensate that naturally forms in finite domains of experiments/simulations. Our new theory hinges on: (1) derivation of a spectral diffusion equation when non-local interactions with the condensate become dominant, for the first time systematically formulated for quartet-interaction systems; and (2) careful analysis of the asymptotics of interaction coefficient with a remarkable cancellation of all leading-order terms.
Turbulence effect on disk settling dynamics
Authors: Tinklenberg Amy , Guala Michele , Coletti Filippo
Published: August 2024

Turbulence can have a strong effect on the fall speed of snowflakes and ice crystals. In this experimental study, the behaviour of thin disks falling in homogeneous turbulence is investigated, in a range of parameters relevant to plate crystals. Disks ranging in diameter from 0.3 to 3 mm, and in Reynolds number

$Re = 10\unicode{x2013}435$

, are dispersed in two air turbulence levels, with velocity fluctuations comparable to the terminal velocity. For each case, thousands of trajectories are captured and reconstructed by high-speed laser imaging, allowing for statistical analysis of the translational and rotational dynamics. Air turbulence reduces the disk terminal velocities by up to 35 %, with the largest diameters influenced most significantly, which is primarily attributed to drag nonlinearity. This is evidenced by large lateral excursions of the trajectories, which correlate with cross-flow-induced drag enhancement as reported previously for falling spheres and rising bubbles. As the turbulence intensity is increased, flat-falling behaviour is progressively eliminated and tumbling becomes prevalent. The rotation rates of the tumbling disks, however, remain similar to those displayed in still air. This is due to their large moment of inertia compared to the surrounding fluid, in stark contrast with studies conducted in water. In fact, the observed reduction of settling velocity is opposite to previous findings on disks falling in turbulent water. This emphasizes the importance of the solid-to-fluid density ratio in analogous experiments that aim to mimic the behaviour of frozen hydrometeors.
Trading particle shape with fluid symmetry: on the mobility matrix in 3-D chiral fluids
Authors: Khain Tali , Fruchart Michel , Scheibner Colin , Witten Thomas A. , Vitelli Vincenzo
Published: August 2024

Chiral fluids – such as fluids under rotation or a magnetic field as well as synthetic and biological active fluids – flow in a different way than ordinary ones. Due to symmetries broken at the microscopic level, chiral fluids may have asymmetric stress and viscosity tensors, for example giving rise to a hydrostatic torque or non-dissipative (odd) and parity-violating viscosities. In this article, we investigate the motion of rigid bodies in such an anisotropic fluid in the incompressible Stokes regime through the mobility matrix, which encodes the response of a solid body to forces and torques. We demonstrate how the form of the mobility matrix, which is usually determined by particle geometry, can be analogously controlled by the symmetries of the fluid. By computing the mobility matrix for simple shapes in a three-dimensional (3-D) anisotropic chiral fluid, we predict counterintuitive phenomena such as motion at an angle to the direction of applied forces and spinning under the force of gravity.
Hate speech detection in low-resourced Indian languages: An analysis of transformer-based monolingual and multilingual models with cross-lingual experiments
Authors: Ghosh Koyel , Senapati Apurbalal
Published: August 2024

Warning: This paper is based on hate speech detection and may contain examples of abusive/ offensive phrases.

Cyberbullying, online harassment, etc., via offensive comments are pervasive across different social media platforms like ™Twitter, ™Facebook, ™YouTube, etc. Hateful comments must be detected and eradicated to prevent harassment and violence on social media. In the Natural Language Processing (NLP) domain, the most prevalent task is comment classification, which is challenging, and language models based on transformers are at the forefront of this advancement. This paper intends to analyze the performance of language models based on transformers like BERT, ALBERT, RoBERTa, and DistilBERT on the Indian hate speech datasets over binary classification. Here, we utilize the existing datasets, i.e., HASOC (Hindi and Marathi) and HS-Bangla. So, we evaluate several multilingual language models like MuRIL-BERT, XLM-RoBERTa, etc., few monolingual language models like RoBERTa-Hindi, Maha-BERT (Marathi), Bangla-BERT (Bangla), Assamese-BERT (Assamese), etc., and perform cross-lingual experiment also. For further analyses, we perform multilingual, monolingual, and cross-lingual experiments on our Hate Speech Assamese (HS-Assamese) (Indo-Aryan language family) and Hate Speech Bodo (HS-Bodo) (Sino-Tibetan language family) dataset (HS dataset version 2) also and achieved a promising result. The motivation of the cross-lingual experiment is to encourage researchers to learn about the power of the transformer. Note that no pre-trained language models are currently available for Bodo or any other Sino-Tibetan languages.
MULTIPLICATIVE FUNCTIONSk-ADDITIVE ON GENERALISED OCTAGONAL NUMBERS
Authors: HASANALIZADE ELCHIN , PARK POO-SUNG
Published: August 2024

Let$k\geq 4$be an integer. We prove that the set$\mathcal {O}$of all nonzero generalised octagonal numbers is ak-additive uniqueness set for the set of multiplicative functions. That is, if a multiplicative function$f_k$satisfies the condition$$ \begin{align*} f_k(x_1+x_2+\cdots+x_k)=f_k(x_1)+f_k(x_2)+\cdots+f_k(x_k) \end{align*} $$

for arbitrary$x_1,\ldots ,x_k\in \mathcal {O}$, then$f_k$is the identity function$f_k(n)=n$for all$n\in \mathbb {N}$. We also show that$f_2$and$f_3$are not determined uniquely.
ORGANIC COMPOSITION OR UT PICTURA POESIS? ΖΩΙΟΝ IN ARISTOTLE'S POETICS
Authors: Galván Luis
Published: August 2024

This paper discusses Aristotle's references to a ζῷον in his Poetics (1450b34–51a4 and 1459a20) and evaluates their implications. The usual interpretation, ‘living creature’ or ‘animal’, is one-sided, because the word ζῷον is Aristotle's paradigm of homonymy, applying as it does to both the human being and the drawing (Cat. 1a1–6). After an examination of the two passages containing such references and their contexts, other passages by Aristotle and earlier writers (Plato, Alcidamas and Gorgias) that may shed light on the issue are analysed. The conclusion reflects on the relevance of the interpretation as ‘figure’ for the premises and purpose of the Poetics.
The Remarkably Unremarkable Life of England's First Black Parish Priest
Authors: CHATER KATHLEEN
Published: August 2024

Bryan Mackey (1770–1847) was for years the unremarkable, unremarked rector of a rural parish in Gloucestershire. He has, however, the distinction of apparently being the first priest with African ancestry to be ordained into the Church of England and who then served his entire career in Britain. His life history raises questions about historical racism within the Church and the wider society.
Metazoan endoparasites of snakes from Argentina: Review and checklist with distributional notes and remarks
Authors: Caraballo Juan Nicolás , Ulibarrie Andrés , Hamann Monika , Guerrero Ricardo , Arzamendia Vanesa , González Cynthya Elizabeth
Published: August 2024

This article presents a checklist of metazoan parasites of snakes from Argentina, along with a comprehensive review of the relevant literature published between 1922 and June 2023, covering various aspects of interest. We compiled 34 species of metazoan endoparasites from 28 studies. The subclass Digenea showed the highest number of species (n = 22 species), followed by the phylum Nematoda (n = 8 species), and the subclass Pentastomida (n = 3 species and 1 taxa inquirenda). Dipsadidae was the family of snakes with the most species examined for metazoan endoparasites (n = 20 species). In contrast, Viperidae had the largest number of specimens surveyed (n = 343). Of 23 provinces, 15 (65.2%) presented at least one report of metazoan endoparasites in snakes. The northeastern provinces showed the highest richness of metazoan endoparasites and host diversity. Many articles focused on taxonomy, but studies on parasite ecology were not found. Although taxonomic accuracy was high in most reports, some records were correctly deposited in zoological collections or geo-referenced. This is the first attempt to include all groups of metazoan endoparasites of snakes from Argentina in a single checklist in the last century.
On the question of domestic slaves in late medieval and early modern Zoroastrianism
Authors: Foroutan Kiyan
Published: August 2024

This article collects and analyses passages about male and female domestic slaves in the Persian Rivāyats. The Rivāyats consist of correspondence between Iranian and Indian Zoroastrians (Parsis) from the late fifteenth to the eighteenth centuries ce. In these letters, Parsis sought the opinions of Iranian Zoroastrians on various doctrinal and ritual issues. The passages in question cover a range of subjects, including the issue of converting household slaves to Zoroastrianism, their participation in domestic religious ceremonies, the exposure of their dead bodies in the towers of silence, and marrying female slaves. These references to slaves challenge the conventional narrative that pre-modern Zoroastrians were oppressed, marginalized, and poor communities. This narrative has overshadowed these pieces of evidence and has caused them not to be studied seriously. This paper seeks to go beyond this traditional reconstruction by examining these texts based on their context. The passages reflect the actual socio-religious issues of Zoroastrians, especially Parsis, and demonstrate their participation in the slave-owning milieu of late medieval and early modern Gujarat and Iran rather than mere anachronistic elements or rhetorical tools reflecting a scholastic treatment of a defunct legal question.
Africana Political Theory as Decolonial Critique
Authors: Chevannes Derefe Kimarley
Published: August 2024

This article illuminates a fundamental problem at the core of canonical political theory: the racialization of knowledge. It contends that the history of canonical thought as being necessarily Western and, therefore, European American, means the emergence of epistemic racism produces enormous consequences for the practice of philosophical thought—namely, Africana political theory (APT). Thus, this article raises important questions such as the colonization of reason, as well as the ongoing relationship between political theory and race, such that the specter of anti-black racism manifests and becomes intertwined with the foundations of the canon. Ultimately, the article proffers APT as decolonial critique to complicate and expand the parameters of philosophical practice. The overall consequences for the discipline, its students, and its practitioners actualize an ongoing movement for black liberation.
The Origins of a Fiscal Outlier: The Abandonment of a Federal VAT in the Nixon Presidency
Authors: Mozumi Seiichiro
Published: August 2024

Richard Nixon was the first president who examined the possibility of introducing a value-added tax (VAT) at the federal level in the late twentieth century. By 1970, his administration had considered recommending it alongside other domestic programs to overcome the criticism against the VAT’s regressivity, potential conflict in the federal–state tax authority, and the fragmented decision-making authority between the executive and legislative branches of the government. However, in 1971, the Nixon administration shifted their policy priority toward gaining the middle-class political support by linking local property tax relief to a federal VAT. Although they combined the two measures with a rebate to obtain consent to and confidence in them from the “opponents” among the “internalists” of policymaking and societal actors, their attempt failed to accomplish it. As a result, Nixon abandoned the federal VAT. This abandonment was a missed opportunity to introduce a federal VAT, leading the United States to become a fiscal outlier among Organisation for Economic Co-operation and Development (OECD) countries: it has not yet implemented a national/federal VAT. Furthermore, this outcome marked the origin of certain historical characteristics of the American fiscal state: the use of tax expenditures, “fend-for-yourself federalism,” weak extractive capacity, and fiscal inflexibility.
Relationships Between HCl, H2O, Aerosols, and Temperature in the Martian Atmosphere: 1. Climatological Outlook
Authors: Olsen K. S. , Fedorova A. A. , Kass D. M. , Kleinböhl A. , Trokhimovskiy A. , Korablev O. I. , Montmessin F. , Lefèvre F. , Baggio L. , Alday J. , Belyaev D. A. , Holmes J. A. , Mason J. P. , Streeter P. M. , Rajendran K. , Patel M. R. , Patrakeev A. , Shakun A.
Published: August 2024

Detecting trace gases such as hydrogen chloride (HCl) in Mars' atmosphere is among the primary objectives of the ExoMars Trace Gas Orbiter (TGO) mission. Terrestrially, HCl is closely associated with active volcanic activity, so its detection on Mars was expected to point to some form of active magmatism/outgassing. However, after its discovery using the mid‐infrared channel of the TGO Atmospheric Chemistry Suite (ACS MIR), a clear seasonality was observed, beginning with a sudden increase in HCl abundance from below detection limits to 1–3 ppbv in both hemispheres coincident with the start of dust activity, followed by very sudden and rapid loss at the southern autumnal equinox. In this study, we have investigated the relationship between HCl and atmospheric dust by making comparisons in the vertical distribution of gases measured with ACS and aerosols measured co‐located with the Mars Climate Sounder (MCS). This study includes HCl, water vapor, and ozone measured using ACS MIR, water vapor and temperature measured with the near infrared channel of ACS, and temperature, dust opacity, and water ice opacity measured with MCS. In part 1, we show that dust loading has a strong impact in temperature, which controls the abundance of water ice and water vapor, and that HCl is very closely linked to water activity. In part 2, we investigate the quantitative correlations between each quantity and discuss the possible source and sinks of HCl, their likelihood given the correlations, and any issues arising from them.
Relationships Between HCl, H2O, Aerosols, and Temperature in the Martian Atmosphere: 2. Quantitative Correlations
Authors: Olsen K. S. , Fedorova A. A. , Kass D. M. , Kleinböhl A. , Trokhimovskiy A. , Korablev O. I. , Montmessin F. , Lefèvre F. , Baggio L. , Alday J. , Belyaev D. A. , Holmes J. A. , Mason J. P. , Streeter P. M. , Rajendran K. , Patel M. R. , Patrakeev A. , Shakun A.
Published: August 2024

The detection of hydrogen chloride (HCl) in the atmosphere of Mars was among the primary objectives of the ExoMars Trace Gas Orbiter (TGO) mission. Its discovery using the Atmospheric Chemistry Suite mid‐infrared channel (ACS MIR) showed a distinct seasonality and possible link to dust activity. This paper is part 2 of a study investigating the link between HCl and aerosols by comparing gas measurements made with TGO to dust and water ice opacities measured with the Mars Climate Sounder (MCS). In part 1, we showed, and compared, the seasonal evolution of vertical profiles of HCl, water vapor, temperature, dust opacity, and water ice opacity over the dusty periods around perihelion (solar longitudes 180°–360°) across Mars years 34–36. In part 2, we investigated the quantitative correlations in the vertical distribution between each quantity, as well as ozone. We show that there is a strong positive correlation between HCl and water vapor, which is expected due to fast photochemical production rates for HCl when reacting with water vapor photolysis products. We also show a strong positive correlation between water vapor and temperature, but are unable to show any correlation between temperature and HCl. There are weak correlations between the opacities of dust and water ice, and dust and water vapor, but only very low correlations between dust and HCl. We close with a discussion of possible sources and sinks and that interactions between HCl and water ice are the most likely for both, given the inter‐comparison.
Postfire Sediment Mobilization and Its Downstream Implications Across California, 1984–2021
Authors: Dow H. W. , East A. E. , Sankey J. B. , Warrick J. A. , Kostelnik J. , Lindsay D. N. , Kean J. W.
Published: August 2024

Fire facilitates erosion through changes in vegetation and soil, with major postfire erosion commonly occurring even with moderate rainfall. As climate warms, the western United States (U.S.) is experiencing an intensifying fire regime and increasing frequency of extreme rain. We evaluated whether these hydroclimatic changes are evident in patterns of postfire erosion by modeling hillslope erosion following all wildfires larger than 100 km2 in California from 1984 to 2021. Our results show that annual statewide postfire hillslope erosion has increased significantly over time. To supplement the hillslope erosion modeling, we compiled modeled and measured postfire debris‐flow volumes. We find that, in northern California, more than 50% of fires triggering the top 20 values of sediment mass and sediment yield occurred in the most recent decade (between 2011 and 2021). In southern California, the postfire sediment budget was dominated by debris flows, which showed no temporal trend. Our analysis reveals that 57% of postfire sediment erosion statewide occurred upstream of reservoirs, indicating potential impacts to reservoir storage capacity and thus increased risk to water‐resource security with ongoing climate change.
Markers of positive affect and brain state synchrony discriminate melancholic from non-melancholic depression using naturalistic stimuli
Authors: Mosley Philip E. , van der Meer Johan N. , Hamilton Lachlan H. W. , Fripp Jurgen , Parker Stephen , Jeganathan Jayson , Breakspear Michael , Parker Richard , Holland Rebecca , Mitchell Brittany L. , Byrne Enda , Hickie Ian B. , Medland Sarah E. , Martin Nicholas G. , Cocchi Luca
Published: August 2024

Melancholia has been proposed as a qualitatively distinct depressive subtype associated with a characteristic symptom profile (psychomotor retardation, profound anhedonia) and a better response to biological therapies. Existing work has suggested that individuals with melancholia are blunted in their display of positive emotions and differ in their neural response to emotionally evocative stimuli. Here, we unify these brain and behavioural findings amongst a carefully phenotyped group of seventy depressed participants, drawn from an established Australian database (the Australian Genetics of Depression Study) and further enriched for melancholia (high ratings of psychomotor retardation and anhedonia). Melancholic (n = 30) or non-melancholic status (n = 40) was defined using a semi-structured interview (the Sydney Melancholia Prototype Index). Complex facial expressions were captured whilst participants watched a movie clip of a comedian and classified using a machine learning algorithm. Subsequently, the dynamics of sequential changes in brain activity were modelled during the viewing of an emotionally evocative movie in the MRI scanner. We found a quantitative reduction in positive facial expressivity amongst participants with melancholia, combined with differences in the synchronous expression of brain states during positive epochs of the movie. In non-melancholic depression, the display of positive affect was inversely related to the activity of cerebellar regions implicated in the processing of affect. However, this relationship was reduced in those with a melancholic phenotype. Our multimodal findings show differences in evaluative and motoric domains between melancholic and non-melancholic depression through engagement in ecologically valid tasks that evoke positive emotion. These findings provide new markers to stratify depression and an opportunity to support the development of targeted interventions.
Hemoglobin glycation index and cardiovascular outcomes in patients with diabetes and coronary artery disease: insights from a large cohort study
Authors: Lin Zhangyu , He Jining , Yuan Sheng , Song Chenxi , Bian Xiaohui , Yang Min , Dou Kefei
Published: August 2024

Background/objectives

The hemoglobin glycation index (HGI) has been demonstrated to serve as a substitute for the individual bias in glycosylated hemoglobin A1c (HbA1c). Our objective was to assess the correlation between HGI and cardiovascular (CV) outcomes in patients with diabetes and coronary artery disease (CAD).

Subjects/methods

We sequentially recruited 11921 patients with diabetes and CAD at Fuwai Hospital. The patients were categorized into five groups based on their HGI quintiles, ranging from Q1 to Q5. The primary endpoint was the occurrence of major adverse cardiac events (MACEs), which included CV death and nonfatal myocardial infarction.

Results

During the median 3-year follow-up, 327 (2.7%) MACEs were observed. A U-shaped relationship between HGI and 3-year MACEs was demonstrated by restricted cubic spline (RCS) after multivariable adjustment (nonlinear P = 0.014). The Kaplan-Meier curves demonstrated that the Q2 group had the lowest risk of MACE (P = 0.006). When comparing the HGI Q2 group, multivariable Cox regression models showed that both low (Q1) and high (Q4 or Q5) HGI were linked to a higher risk of MACEs (all P < 0.05). Patients with a low HGI (Q1) had a significantly increased risk of all-cause and CV death, with a 1.70-fold increase in both cases (both P < 0.05).

Conclusions

In individuals with diabetes and established CAD, HGI levels were found to have a U-shaped relationship with the occurrence of MACEs over a period of three years. Significantly, those with low HGI had an increased risk of CV death.
Circ-0044539 promotes lymph node metastasis of hepatocellular carcinoma through exosomal-miR-29a-3p
Authors: Yang Yi , Chen Xue-Qin , Jia Ya-Xun , Ma Jie , Xu Di , Xiang Zuo-Lin
Published: August 2024

Lymph node metastasis (LNM) is a common invasive feature of hepatocellular carcinoma (HCC) associated with poor clinical outcomes. Through microarray profiling and bioinformatic analyses, we identified the circ-0044539-miR-29a-3p-VEGFA axis as a potential key factor in the progression of HCC LNM. In HCC cells and nude mice, circ-0044539 downregulation or miR-29a-3p upregulation was associated with small tumor size, PI3K-AKT-mTOR pathway inactivation, and downregulation of the key LNM factors (HIF-1α and CXCR4). Furthermore, circ-0044539 was also responsible for exosomal miR-29a-3p secretion. Exosomal miR-29a-3p was then observed to migrate to the LNs and downregulate High-mobility group box transcription factor 1 (Hbp1) in Polymorphonuclear Myeloid-derived suppressor cells (PMN-MDSCs), inducing the formation of a microenvironment suitable for tumor colonization. Overall, circ-0044539 promotes HCC cell LNM abilities and induces an immune-suppressive environment in LNs through exosomes, highlighting its potential as a target for HCC LNM and HCC immunotherapy.