bluuebunny/crossref_metadata_2025 huggingface dataset:
The association of psychological well-being and fertility intention in parents of children with intellectual disability
Authors: Sheidanik Sepideh , Savabi-Esfahani Mitra , Ghamarani Amir , Erfani Amir
Published: January 2021

INTRODUCTION:

Childbearing is an important event in a couple's life. The parents might have children with disability that affected on their well-being after the children's birth. Well-being considered as an important aspect of a couple's quality of life which may alter the future of their fertility. The present study was conducted to the association of psychological well-being and fertility intention in parents with educable intellectually disabled children.

METHODS:

The study was a cross-sectional descriptive research conducted on parents of children with intellectual disability (n = 386). Parents were selected randomly of schools of exceptional education and welfare. The data were collected using Ryff's scale of psychological well-being, demographic information, and fertility intention questionnaire. Data were analyzed using descriptive and analytical tests including independent t-test, Chi-square test, Mann–Whitney U-test, and Logistic regression.

RESULTS:

The majority of parents (83.9%) reported the negative infertility intention. Despite the mean score of well-being in parents without fertility intention (75.71 ± 11.67) was lower than parents with fertility intention (76.90 ± 11.27), the difference was not statistically significant (P > 0.05). The logistic regression analysis indicated that the parents' age and number of children with intellectual disability were predictors of fertility intention (P < 0.05), and their increase decreased the fertility intention.

CONCLUSION:

It seems that the lack of difference in psychological well-being scores between the two groups of parents might be due to the equal severity of disability in children. The results also indicated parents' age and the number of children correlated with fertility intention. The findings can be used to advance counseling programs in the field of healthy reproduction for this group of parents.
The effect of complementary medicine on maternal health promotion
Authors: Hafizi Leili , Razmjoo Nastaran , Yousefi Fatemeh , Azizi Hoda
Published: January 2021

BACKGROUND:

During the immediate post delivery period, women are particularly susceptible to distension of the bladder. Complementary and alternative medicine is becoming an established intervention modality within the contemporary health care system. However, very little is known about the impact of foot reflexology on the urinary system. The aim of this study was to evaluate the effect of the most popular type of complementary therapy (the foot reflexology) on first voiding time following elective cesarean section without urinary catheter.

METHODS:

This experimental study was performed on 61 pregnant women in Pastor Hospital, Mashhad, Iran, who met the inclusion criteria. Accordingly, participants were randomly allotted to either treatment or control groups. The intervention group received a single 20-min foot re?exology session at 2–3 h after the surgery. The time taken for first void was recorded by research assistant that blinded to the allocation of groups. The findings were recorded and analyzed with the SPSS software by using of Chi-square, independent t-test, Mann–Whitney, and Fisher exact methods P < 0.05 was considered as statistically significant.

RESULTS:

Using General Linear Model (GLM) for controlling of confounding variables, the results of t-test showed significant differences between two groups in terms of first voiding time (P = 0.001) following surgery.

CONCLUSION:

It seems that the use of foot reflexology as a nursing care plan to prevent urinary retention after cesarean section without urinary catheter does shorten first voiding time and increase maternal satisfaction.
A rare presentation of hydatid cyst, involvement of uncommon sites with sparing of typical locations
Authors: Karami Mehdi , Sadatmadani Seyedeh Fatemeh , Kouhi Hossein , Sadeghi Bahar , Rostamiyan Zeynab , Hashemzadeh Mozhdeh
Published: January 2021

Hydatid cyst (HC) is a serious health problem in endemic areas. Liver and lung are the most common involved organs while the involvement of muscles, heart, kidney, brain, and spleen is rare. The involvement of these rare locations for HC is mostly in association with infestation of common sites. We report a case of 43-year-old man with a history of surgery of HC in brain and heart who complained from chest pain. In imaging modalities, three cystic lesions were seen in heart and kidney which were confirmed to be recurrence of HC by serologic tests. However, no evidence of involvement of liver and lungs as the most common infected organs of HC was seen in recent and previous imaging mo®dalities. The patient refused another surgery and just accepted anthelmintic drugs. The practical point of this case report is that when we see any cystic lesion in imaging modalities in uncommon sites for HC, while common sites are spare, we should still consider the possibility of HC and not rule out it just because of lack of simultaneous infestation of its common involved organs.
The effects of spirulina under high-intensity interval training on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females
Authors: Golestani Fateme , Mogharnasi Mehdi , Erfani-Far Mahboube , Abtahi-Eivari Seyed Hossein
Published: January 2021

Background:

We investigated the effects of spirulina under high-intensity interval training (HIIT) on levels of nesfatin-1, omentin-1, and lipid profiles in overweight and obese females.

Materials and Methods:

This is a randomized, quasi-experimental controlled, single-blind with a pre- and post-test design, in which twenty overweight and obese women (body mass index = 29.32 ± 3.01 kg/m2, age = 21.55 ± 1.76 years), were randomly divided into the following groups: HIIT + spirulina (n = 10) and HIIT + placebo (n = 10). Running anaerobic sprint test was used for HIIT protocol consisting of six intervals at 35 m maximal speed runs, with a rest of 10 s in each trial (3 times/week, 4 weeks). HIIT + spirulina group received 500 mg of the spirulina pills twice daily for 4 weeks and the second group took placebo.

Results:

There was a significant increase in serum levels of nesfatin-1 in HIIT + spirulina (P < 0.0001) but not in HIIT + placebo (P = 0.61) group. Furthermore, results indicated a significant difference between two groups with respect to serum levels of nesfatin-1 (P = 0.04). Serum levels of omentin-1 significantly increased in both groups (P < 0.05). However, there was no significant difference between two groups (P = 0.49). In addition, results showed no significant inter- and intra-group differences in total cholesterol levels, triglycerides, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol between groups (P > 0.05).

Conclusion:

The spirulina under HIIT increased levels of nesfatin-1 and omentin-1 with no effects on the levels of lipid profiles in overweight and obese females.
Correlation of –160C > A and –347GA > G polymorphisms in E-cadherin gene and gastric cancer in north of Iran
Authors: Shekarriz Ramin , Alikhani Reza , Ghasemi Mohaddeseh , Navaei Reza Alizadeh , Hashemi-Soteh Mohammad Bagher
Published: January 2021

Background:

E-cadherin (CDH1 gene) is a protein involved in cell-cell adhesion. There are reports on the association of –160C > A (rs16260) and –347GA > G (rs5030625) polymorphisms in the 5′-promoter region of the CDH1 gene with tumor development and progression of gastric cancer. This study aimed to examine the potential relationship between these two polymorphisms and gastric cancer in patients from Mazandaran province, Northern Iran.

Materials and Methods:

A case–control study was conducted to test 97 patients and 95 healthy controls. Genomic DNA was extracted from peripheral blood followed by polymerase chain reaction amplification. Genotyping analysis was carried out using restriction fragment length polymorphism analysis for two potentially functional polymorphisms.

Results:

Heterozygous genotype GA/G versus GA/GA of rs5030625 (–347 GA > G) was found to be associated with increased risk of gastric cancer in the people studied (odds ratio = 5.73, 95% confidence interval = 2.11–15.56, P = 0.001). Furthermore, AA or CA genotype in –160C > A polymorphism did not show any increased risk of gastric cancer (P = 0.559).

Conclusion:

The present study revealed that GA/G genotype of rs5030625 (–347 GA > G) polymorphism is associated with gastric cancer in Northern Iran.
Impact of Antenatal Care on Pregnancy Outcomes
Authors: Keya Tahmina Afrose , Fernandez Kevin , Kharkwal Kailash C. , Habib Nasrin
Published: January 2021

Background:

Malaysia has a high standard of health-care system, including antenatal care (ANC) services.

Objective:

This cross-sectional study was carried out to assess the impact of regular ANC visits on outcome in a rural community in Malaysia from September to November, 2019, in village Kampung Merbok in Kedah, Malaysia.

Method and Materials:

A pretested semi-structured questionnaire was used as a tool for data collection among the women who gave birth in public or private health-care centers. Association between the various components of ANC and pregnancy outcome was examined using multivariate logistic regression analysis, and Chi-square test/Fisher's exact test was used to interpret the association between the ANC visits and the outcome variables.

Result:

Among the respondents, 39 (78%) had more than four ANC visits. Fourteen (28%) respondents had adverse pregnancy outcome. All nonattendees had adverse outcome. Only 6 (12%) women (95% confidence interval: 3.22, 20.78) had a history of cesarean section. This study found statistically significant association between maternal ANC visits and maternal and neonatal outcome variables (P < 0.05). Pearson's correlation test also revealed the strong relationship between ANC and the outcome variables (P < 0.0001).

Conclusion:

In this study, mothers having regular ANC visits experienced better pregnancy outcome compared to those nonattendees. Nevertheless, it is necessary to adhere to a minimum level of four ANC visits for all pregnant women. More health promotion programs are required focusing on improving women's awareness of the necessity of ANC throughout their pregnancy.
Intelligent Internet of Things and Advanced Machine Learning Techniques for COVID-19
Authors: Chakraborty Chinmay , Naser Abougreen Arij
Published: January 2021

INTRODUCTION: Coronavirus disease (COVID-19) has recently emerged around the world. The beginning of the disease was in the Chinese city of Wuhan and then it has been spread and became a global epidemic. An early diagnosis of COVID-19 disease is absolutely necessary to control the epidemic.OBJECTIVES: The aim of this paper is to present a review of the contribution of machine learning (ML) and IoT to confront the epidemic.METHODS: Diagnosis using real-time reverse transcriptase-polymerase chain reaction (RT-PCR) is a definite diagnosis, but this method takes time, while a diagnosis using a computed tomography (CT) scan is a faster approach to diagnosis. However, a large number of patients need a CT scan, which puts a lot of pressure on the radiologist so visual fatigue may lead to diagnostic errors so there is an urgent need for additional solutions. Artificial intelligence (AI) is an efficient tool to combat COVID-19 disease. Computer scientists have been developing many systems to handle this epidemic.RESULTS: It was found that ML is an efficient and powerful AI technology that can be used for trustworthy COVID-19 detecting and diagnosis from X-ray and CT images and it can be a potential method for diagnosis in the radiology department. In addition, ML can be used in segmentation, prediction purposes for COVID-19. Furthermore, ML can effectively support drug discovery procedure and can reduce clinical failures.CONCLUSION: IoT has a significant role in monitoring an individual's health and COVID-19 diagnosis. This paper also highlights the challenges of employing ML and intelligent IoT for fighting COVID-19.
The Parisi formula is a Hamilton–Jacobi equation in Wasserstein space
Authors: Mourrat Jean-Christophe
Published: January 2021

The Parisi formula is a self-contained description of the infinite-volume limit of the free energy of mean-field spin glass models. We showthat this quantity can be recast as the solution of a Hamilton–Jacobi equation in the Wasserstein space of probability measures on the positive half-line.
Car Suspension and Handling, Fourth Edition
Authors: Howard Geoffrey , Bastow Donald , Whitehead John Peter ,   MIRA, Ltd
Published: January 2021

Through appendices and diagrams, Car Suspension and Handling, 4th Edition outlines the purpose and history of vehicle suspension systems, while defining the basic parameters of suspension geometry. In addition, the book delves into human sensitivity to vibration, and offers data on durability, tire background information, steering calculations and suspension calculations.
The dynamics of agricultural extension delivery along the value chain: Assessment of agricultural extension activities of MMDAs in Ghana
Authors: Manteaw S.A. , Folitse B.Y. , Anaglo J.N. , Mahama S. , Mingle N.A.
Published: January 2021

This paper assessed agricultural extension delivery in 216 metropolitan, municipal and district assemblies (MMDAs) in Ghana. It examined the extent of balance and the nature of extension delivery with respect to input supplying, production, processing and marketing. A survey of Heads of the Department of Agriculture in 80 MMDAs randomly selected nationwide was conducted using structured questionnaires. The data were triangulated with in-depth interview sessions with farmers, regional extension officers and private extension providers. The study showed a production-oriented nature of extension delivery across the country with 90% of respondents claiming to have focused extension delivery in their localities on production. This had led to the rather inadequate attention directed at processing and value addition on account of limited capacity of agricultural extension agents. While extension on input supplying was observed to be a private sector-driven activity in the hands of input dealers, the study showed limited extension delivery on marketing as most farmers made their own marketing arrangements. This paper makes a strong case for an extension policy that ensures a reasonable balance and one that introduces competitiveness in value chain activities. The paper also calls for sustained institutional capacity building to give providers a more balanced extension delivery.
The Kirchhoff Transformation for Convective-radiative Thermal Problemsin Fins
Authors: Quirino Jonatas Motta , Correa Eduardo Dias , do Lago Sobral Rodolfo
Published: January 2021

- The present work describes the thermal profile of a single dissipation fin, where their surfaces reject heat to the environment. The problem happens in steady state, which is, all the analysis occurs after the thermal distribution reach heat balance considering that the fin dissipates heat by conduction, convection and thermal radiation. Neumann and Dirichlet boundary conditions are established, characterizing that heat dissipation occurs only on the fin faces, in addition to predicting that the ambient temperature is homogeneous. Heat transfer analysis is performed by computational simulations using appropriate numerical methods. The most of solutions in the literature consider some simplifications as constant thermal conductivity and linear boundary conditions, this work addresses this subject. The method applied is the Kirchhoff Transformation, that uses the thermal conductivity variation to define the temperatures values, once the thermal conductivity variate as a temperature function. For the real situation approximation, this work appropriated the silicon as the fin material to consider the temperature function at each point, which makes the equation that governs the non-linear problem. Finally, the comparison of the results obtained with typical results proves that the assumptions of variable thermal conductivity and heat dissipation by thermal radiation are crucial to obtain results that are closer to reality.
The evaluation of nailfold capillaroscopy pattern in patients with fibromyalgia
Authors: Coşkun Benlidayı İlke , Kayacan Erdoğan Esra , Sarıyıldız Aylin
Published: January 2021

Objectives: This study aims to evaluate nailfold capillaroscopic pattern in patents with fibromyalgia and to assess the relation of capillaroscopic parameters with clinical variables and disease-related measures.

Patients and methods: This cross-sectional, case-control study included 60 participants (4 males, 56 females; mean age: 44.0±8.2 years; range, 26 to 64 years) between August 2019 and November 2019. All participants were divided into two groups as the primary fibromyalgia group (n=30) who met the 2016 modified American College of Rheumatology Diagnostic Criteria for Fibromyalgia and the control group (n=30) consisting of age- and sex-matched healthy individuals. Nailfold capillaroscopy was performed by a digital microscope under a magnification of 200X. Capillary density, capillary loop diameter, number of dilated, giant and neoangiogenic capillaries, capillary shape, number of avascular areas, micro-aneurysms and micro-hemorrhages were evaluated by an assessor who was blind to the group allocation. In the fibromyalgia group, Widespread Pain Index, Symptom Severity Scale scores, and Fibromyalgia Severity scores were calculated. Health status and presence of benign joint hypermobility syndrome (BJHS) were evaluated using the Fibromyalgia Impact Questionnaire (FIQ) and revised Brighton criteria, respectively.

Results: Of the capillaroscopic parameters, the mean capillary loop diameter, number of micro-aneurysms, avascular areas, and neoangiogenic capillaries were significantly higher in the patient group compared to the controls (p<0.001, p=0.016, p=0.038, and p=0.04, respectively). Nailfold capillaroscopic findings did not significantly differ between the patients with (n=16) and without concomitant BJHS (n=14). Of the disease-related measures, only FIQ score showed a weak correlation with the number of dilated capillaries (p=0.324).

Conclusion: Patients with fibromyalgia have distinct capillaroscopic patterns than healthy population. Capillaroscopic features, in general, are not related to clinical variables and disease-related measures.
Cerebral Haemorrhage in a Young Male due to Idiopathic Unilateral Sigmoid and Transverse Sinus Thrombosis, Treated with Anticoagulation
Authors:   Department of General Medicine, Wexford General Hospital, Ireland, Sharjeel Shaikh , Zulfiqar Ali Sandhu ,   Department of General Medicine, Wexford General Hospital, Ireland, Muhammad Siddique ,   Department of General Medicine, Wexford General Hospital, Ireland
Published: January 2021

Cerebral venous sinus thrombosis is a rare but serious disorder. Most cases are linked to thrombophilias, pregnancy, infection and malignancy. It has a remarkably varied clinical presentation and is challenging to diagnose. It can be complicated by haemorrhage which makes the treatment decisions more challenging and difficult. Excellent functional recovery is likely with early recognition and treatment of the underlying aetiology.
Litigation for Health Technology Accessibility: A Tool for Inequality? Reflections Based on Case Study Analysis
Authors:   Department of Medical Science, National University of La Plata, Argentina, Gustavo H Marin ,   CONICET: National Scientific and Technical Research Council, Argentina, Lupe Marin ,   Department of Medical Science, National University of La Plata, Argentina,   CIC: Scientific Research Committee, Buenos Aires, Argentina, Daniel Agüero ,   National University of Arturo Jauretche, Florencio Varela, Argentina, Gina Marin ,   Department of Medical Science, National University of La Plata, Argentina, Mariana Pagnotta ,   Department of Medical Science, National University of La Plata, Argentina, Luis Blanco ,   Department of Medical Science, National University of La Plata, Argentina
Published: January 2021

INTRODUCTION The objective of this work is to analyze the characteristics of litigation for access to health’s goods and services in the Social Health Insurance (SHI) of Buenos Aires, Argentina. METHOD Descriptive study with analytical stage, performed in SHI, analyzing litigation done by beneficiaries along 15-years period to obtain goods or service from health managers. Variables explored were: Reason for litigation, delay time in case resolution, final result of judicial sentence, judges, lawyers and intervening professionals, income level of beneficiaries who started the litigation. RESULT 825 cases were analyzed during the study period according the method described. Demands increased 29.2 ±% per year. Medicines were the goods that most requested legal protection resources (32.5%). 51.9% of these litigations were due to medicines that have less than 24 months of registration by the National Regulatory Agency. The average delay for the final resolution of the procedure was 3.7 months. Judge's sentence was favorable to the beneficiaries in 97.4%. Although there are 27 judicial departments and many courts in each one; cases were concentrated in 47.4% only 2 very few courts. Litigation cases promoted by 112 out of the 15000 doctors that provides services to the SHI. In 73.7% of the cases, beneficiaries that litigated had a salary that exceed 4 times the minimum wage, and only 3.2% of them had low income. CONCLUSION We show how legal appeals might be working as an inverse strategy to the one desired, transferring collective resources belonging to the entire population, towards an specific demand from the most economically wealthy sector of society. As long as access to health care litigation maintains its current individualistic pattern, it will hardly be able to develop its full potential to guarantee effective respect for the collective right to access to goods that beneficiary the whole community.
A Quantitative Assessment of Apically Extruded Debris Associated with Different Retreatment Systems with and without Solvent in vitro Study
Authors:   Department of Endodontics, Dammam Medical Complex, MOH, Dammam, Saudi Arabia, Mustafa A Aldajani , Shibu Thomas Mathew ,   Department of Endodontics, Riyadh Elm University, Riyadh, Saudi Arabia
Published: January 2021

INTRODUCTION Various kinds of rotary instrument and technique are used for mechanical preparation of canal during root canal treatment. These instrument techniques may produce and push debris out of the canal. The purpose of this study was to evaluate the amount of apically extruded debris during retreatment using deferent rotary system (PTG & Hyflex EDM) and also to assess the influence of solvent on apical extrusion. MATERIAL AND METHOD 60 freshly extracted human single root premolar were used in the study. All teeth were instrumented using PTN and obturated by AH plus with single matching GP cone. The samples were randomly divided into two groups for retreatment using Hyflex EDM, PTG with and without solvent. GIA (Hyflex EDM with solvent), G1B (PTG with solvent), G2A (Hyflex EDM without solvent) and G2B (PTG without solvent). Debris extruded from apical foramen was calculated into pre-post weight Eppendorf tube which were stored in dissector at 70° for each vail and mean value was calculated. the different between the weight of vail (pre-post weight) represent the weight of debris extruded from apical foramen. RESULT AND CONCLUSION The data obtained were analyzed statistically using (ANOVA) and Tukey post HSD test. The result show that all groups induced extrusion of debris. Hyflex EDM (G2A) without solvent has statistically the lowest mean value of apically extrusion compared to all other groups, followed by PTG (G2B) without solvent, PTG (G1B) with solvent. Hyflex EDM (G1A) with solvent had the statistically highest mean value of apically extruded debris.
Verifying the Accuracy of Digital Goniometer Range of Motion Measurements for In-Person and Telemedicine Visits
Authors:   Department of Physics, Hamline University, Saint Paul, Minnesota, USA, Zack Langton , Mari Johnson ,   Department of Physics, Hamline University, Saint Paul, Minnesota, USA, Zach Reed ,   Department of Physics, Hamline University, Saint Paul, Minnesota, USA, John Alchemy ,   RateFast Corporation, Santa Rosa, USA, Jerry Artz ,   Department of Physics, Hamline University, Saint Paul, Minnesota, USA, Bruce Bolon ,   Department of Physics, Hamline University, Saint Paul, Minnesota, USA
Published: January 2021

INTRODUCTION This paper offers empirical evidence of the accuracy of the clinical application of the RateFast Goniometer smartphone app. Using multiple comparative measures and interrater reliability measures, this paper investigates the effective ness of this digital goniometer app for physicians practicing in both the office and in telemedicine clinical settings. METHODS Three experiments were performed to test the reliability of the RateFast Goniometer app. The first involved measuring preset angles to test its accuracy. The second experiment involved measuring randomly drawn angles to determine if switching users has any effect on the results. The last experiment measured shoulder angles (flexion and extension planes) of 53 volunteers to determine the accuracy of the RateFast Goniometer app in both haptic mode (for use in an in -person clinical setting) and camera mode (for use in a telemedicine clinical setting). RESULT In the first experiment, the average difference between measurements was 0.6° and the average standard deviation was 0.3°. In the second experiment, the angles measured with the RateFast goniometer were less than those measured with a protractor, averaging to a difference of 0.9°. In the third experiment, the haptic mode measurements and the camera mode measurements had an average difference of 1.2° and the standard deviation of the difference between haptic and camera measurements was determined to be 4.7° across all volunteers. CONCLUSION In all three experiments, the error rate found using the RateFast Goniometer app which is within the error tolerance according to the AMA Guides to the Evaluation of Permanent Impairment, Fifth Edition (AMA Guides), which stipulates that measurements of shoulder angles must be within 10% of one another. The RateFast Goniometer app and similar digital goniometer applications can be used to accurately measure angles in both in -person and telemedicine settings according to the standards of accuracy set forth in the AMA Guides.
The influence of Organizational Support and Management of Employee Performance Marketing in Mediation by Competence
Authors: - Magus Sitindaon , Hery Winoto Tj  , Melitina Tecualu
Published: January 2021

These studies identify and analyze the implications of organizational support, management support, and employee competence on employee performance marketing. The study population was all employees of the marketing BPR Nusantara Bona Pasogit Group Region of West Java and Banten, which amounted to 115 people. Probability sampling technique is made to sampling, a total of 115 respondents who are employees of the marketing BPR Nusantara Bona Pasogit Group Region of West Java and Banten became the sample in the study. This study uses the approach of analysis of structural equation (SEM) using smartPLS. The results of the analysis indicates organizational support has an influence on employee performance marketing at BPR Nusantara Bona Pasogit (NBP) Group Region of West Java and Banten, as well as management support affect the performance of employees marketing at BPR Nusantara Bona Pasogit (NBP) Group Region of West Java and Banten.Disampingitu found also that the support of the organization affect the competence of employees of marketing at BPR Nusantara Bona Pasogit (NBP) Group Region of West Java and Banten.
The Influence of Capital and Work Environment on The Performance of MSME Employees of Bogor Regency West Java Province by Covariable Marketing
Authors: Ismartaya
Published: January 2021

Micro, small and medium enterprises or MSMEs in Indonesia each year increase. The increasing number of MSMEs still needs to experience intensive assistance in order to achieve independent, resilient, and quality MSMEs. Employee performance is a form of employee achievement after going through various stages in the work process. Based on the observations, researchers showed that the performance of MSME employees in Babakan Madang subdistrict and Cisarua Sub-District of Bogor Regency was not optimal. This is allegedly due to being influenced by capital, work environment, and marketing. The formulation of problems in this research is whether the capital and work environment can affect the performance of employees directly or through the marketing of MSMEs in two sub-districts in Bogor Regency.

This study aims to find out the influence of capital and work environment on employee performance with marketing co-operation on MSMEs Bogor Regency, this research uses the archework of The Posttest Only Control Group with marketing covariance. Data collection techniques use interviews and questionnaires, while sampling techniques use non probability sampling with a sample number of 72 people.

The results showed that capital and work environment have a positive and significant effect on employee performance through marketing. This can be seen from the results of simple linear regression analysis, multiple linear regression, t test, determination coefficient test, sobel test and path analysis. Marketing as a moderator variable mediates between capital to employee performance that is partial mediation and marketing as moderator variables that mediate between the work environment and employee performance, both of which are full mediation.
How Big The Role of Credit Risk, Liquidity Risk and Capital Have an Effect On The Profitability of The 10 Largestt Bank in Indonesia
Authors: - Irawati Junaeni
Published: January 2021

The purpose of this research is to analyze how the effect of credit risk, liquidity risk, bank capital, on profitability. The ratio used to measure credit risk using the Non Performing Loan (NPL), liquidity risk using the Loan to Funding Ratio ( LFR) and bank capital using the Capital Adequacy Ratio (CAR). The sample in this study were the 10 largest banks in Indonesia based on total assets. The analysis technique used in this research is panel data regression with fixed effects. The data processing tool used in this study is the Eviews 10 program. The partial test results show that the variables of credit risk and bank capital have an effect on profitabilityas measured by Return on Assets (ROA). Credit risk shows a negative and significant effect on profitability. And bank capital has a positive and significant effect on profitability. Meanwhile, liquidity risk has no significant effect on profitability. Simultaneously, the variables of credit risk, liquidity risk and capital have an effect of 90.17% on profitability. The remaining 9.83% was influenced by other factors not examined in this study
Perbandingan Gambaran Histopatologi Mukosa Kolon Tikus Putih (Rattus Norvegicus) Galur Wistar setelah Dilakukan Washout antara yang Menggunakan Nacl 0,9% dan Larutan Garam Meja 1%
Authors: Tanzil Lindayanti , Diposarosa Rizki , Yantisetiasti Anglita
Published: January 2021

Pendahuluan. Irigasi usus melalui rektum atau washout merupakan suatu prosedur menggunakan sebuah pipa yang dimasukkan melalui anus dan sejumlah cairan dimasukkan melalui pipa tersebut dengan tujuan untuk membersikan usus. NaCl 0,9% sering digunakan pada pasien–pasien penderita penyakit Hirschsprung sebagai cairan washout. Ada berbagai jenis cairan washout yang digunakan, beberapa diantaranya berupa cairan siap pakai yang dapat dibeli di apotek atau toko obat, cairan lainnya dapat dibuat di rumah yaitu larutan garam. Larutan garam ini dianggap sama dengan NaCl 0,9%. Larutan ini selain mudah dibuat dengan biaya yang relatif lebih rendah, tentu saja diharapkan efektivitasnya sama dengan NaCl 0,9%. Namun, garam yang beredar di Indonesia sebagian besar telah mengalami fortifikasi iodium.Tujuan penelitian ini untuk melihat perubahan histopatologi setelah dilakukan washout menggunakan larutan garam meja 1% dibandingkan dengan NaCl 0,9%.

Metode. Penelitian ini merupakan penelitian eksperimental menggunakan 12 tikus Wistar yang terbagi dalam 2 kelompok yaitu kelompok yang dilakukan washout menggunakan NaCl 0,9% dan kelompok yang dilakukan washout menggunakan larutan garam meja 1%. Setelah kedua kelompok dilakukan washout, sampel jaringan diambil dari kolon kemudian dilakukan pemeriksaan histopatologi untuk melihat gambaran kongesti, edema dan inflamasi pada mukosa kolon tikus. Analisis statistik menggunakan Mann whitney dan Independent–T test, signifikan jika p<0,05.

Hasil. Variabel kongesti, edema dan inflamasi pada kelompok NaCl 0,9% mempunyai skor rata–rata yang lebih tinggi dibandingkan kelompok larutan garam meja 1%. Berdasarkan hasil uji statistik tidak terdapat perbedaan yang bermakna antara kedua kelompok (kongesti p=0,065,  edema p=0,306, inflamasi p=0,296.

Kesimpulan. Tidak terdapat perbedaan histopatologi yang bermakna antara penggunaan NaCl 0,9% dan larutan garam meja 1% sebagai cairan washout
NUEVAS FUENTES DE ANTIOXIDANTES NATURALES: CARACTERIZACIÓN DE COMPUESTOS BIOACTIVOS EN CINCO FRUTOS NATIVOS DE CHILE
Authors: Romero Román ME. , Noriega Vásquez F. , Farías Villagra M. , Jara Zapata P. , Vera Flores B. , López Belchi MD.
Published: January 2021

Diferentes berries de la zona centro y sur de Chile fueron analizados con el fin de buscar fuentes promisorias de polifenoles con clara actividad sobre la salud humana. Se estudiaron cinco bayas nativas: arrayan, frutilla blanca, murtilla y calafate, y un berry tradicional (uva tintorera). Se determinó in vitro sus propiedades antioxidantes según el ensayo de polifenoles totales de Folin Ciocalteu, antocianinas por pH diferencial, capacidad antioxidante por medición de capacidad de reducción del radical libre 2.2-difenil-1- picrilhidracilo (DPPH) y poder de reducción férrica (FRAP) y perfil químico por HPLC-DAD. De los cinco berries, calafate registró el valor más alto (1066,4 ± 24,9 mg GAE/100g de muestra) para polifenoles totales y antocianinas (1031,9 ± 48,1 mg de cianidina-3-glucósido/100g de muestra) seguido por uva tintorera. Calafate presentó excelente poder reductor (11279,2 ± 2027,4 μmol Trolox/100g ensayo FRAP y 5235,0 ±445,9, μmol/100g en DPPH). El perfil químico de antocianinas mostró delfinidina, cianidina, malvidina, petunidina, peonidina y pelargonidina en los cinco berries. Alrededor de 30 flavonoles derivados de quercetina, myricetina e isorhamnetina fueron identificados así cómo elagitaninos presentes en frutilla blanca, compuestos muy interesantes para estudios posteriores. Estos resultados contribuyen a destacar el uso potencial de estos berries como alimentos funcionales.
Theoretical Foundations of Psychology in Islamic Civilization the Case Historical Psychology
Authors:   Department of Humanity, Islamic Azad University Central Tehran Branch, Tehran, Iran, Shahidipak Mohammadreza
Published: January 2021

The most ancient science that is still at the forefront of scientific research is psychology, because despite the inherent difference between the term psychology in the modern period with ancient period and medieval period, word psychology is used in the same sense in all three periods. This word, which is the root of term psychology, reaches Aristotle’s teachings in the book of soul. The hypothesis of present study is innovative services of Islamic civilization in the field of psychology and especially, emergence branch of psychology in Islamic civilization that has studied the behavior of politicians and various societies in moments of history as laws and general traditions that can be generalized to human behavior throughout time. The materials of this research are found in medieval literature and humanities texts produced by scholars of Islamic civilization. AL-Jahiz (869AD), the leader of Arabic prose and literatur , considers the method of fourth caliph, Ali ( 661 AD ) in dividing, recognizing and defining the behavior and psyche of individuals, people and cities as special, distinctive and unique that has analyzed and explained the behavior of city and its citizens and their properties in Egypt, Syria, Kufa, Mecca, Medina, some cities of Mesopotamia and has examined the specific behavior of politicians who have been at the helm of government power. The behavior of these people is at a moment in history that has an international impact. The present study is a brief explanation of the three scientific achievements of Islamic civilization in the Middle Ages, which is still useful in theoretical and clinical psychology; 1- Classification of human behavior within the values of ethics and providing a theoretical solution for their treatment by any scholars of Islamic civilization. 2- The initiative of the science of historical political psychology. 3-Report of Avicenna (1037 AD) initiative in clinical psychology research in the field of sleep, neurology, and various mental disorders such as depression, insanity, etc. and clinical ways of treating them. The empirical study of the soul by Avicenna has always been of interest to scholars and has been researched and tested in the Middle Ages by order of Frederick II (1250.AD).
Healthcare For Oncological Patient
Authors:   Independent Researcher, Croatia, Franjic Siniša
Published: January 2021

Despite the constant advancement of medicine in the fields of detection, diagnostic options, and modern forms of treatment, the incidence and mortality of malignancies is in an upward trajectory. The fact of the existence of a malignant disease in the patient results in shock, disbelief and fear, and fright of pain, suffering, and possible death. There is frequent anger and regret about interrupting the usual lifestyle and disrupting life plans. These are normal reactions and with the support of the family and the environment, affected person are successfully dealing with these difficulties
Dynamics of the Autoimmune Response as Specific Differentiation Programs of T-cells in Multiple Sclerosis
Authors:   Department of Pathology Mater dei Hospital, Tal-Qroqq, University of Malta Medical School Msida, Malta, Agius Lawrence M
Published: January 2021

Systems of characterization of antigeniciy implicate active antigen differentiation in terms of the system biology of response to progressive cell injury. Subset incorporation employs active diversification of dysequilibrating sub-populations of given profile exposure of epitope recognition in specific establishment of an immune response. The diversification of such immune responses permit the potential establishment, paradoxicity of systems of adaptation as central to active cell differentiation. Incorporation of injury within the dynamics of evolving epitope exposure guarantee the propagation of the initial establishment of the auto-antigen response within working fabric of a differentiation set of operative interventions in terms of ongoing establishment as specific progression hallmarks of autoimmune disease potentiation
Disease-Modifying Drugs and Stem Cell Therapies for the Treatment of Myelin Degeneration due to Multiple Sclerosis
Authors:   Department of Biological Sciences, College of Science, Clemson University, Clemson, SC 29634-0314, Ioos Darren , Gallicchio Vincent ,   Department of Biological Sciences, College of Science, Clemson University, Clemson, SC 29634-0314
Published: January 2021

Myelin, a modified plasma membrane wrapped around axons, is an essential part of signal propagation in the nervous system. Formed by oligodendrocytes in the central nervous system (CNS) and Schwann cells in the peripheral nervous system (PNS), myelin lowers the amount of energy needed to send or receive signals. Multiple Sclerosis (MS) is an autoimmune, hyperinflammatory disease that attacks the nervous system, specifically myelin. MS is characterized by three types of lesions in the brain and along the blood brain barrier, making it very difficult to diagnose through conventional magnetic resonance imaging (MRI) and even more difficult to treat. It has an unpredictable pathophysiology that cannot be cured by current drug therapies. Stem cell therapies have been heavily researched in recent years to try to combat the autoimmune disease by stopping demyelination and recovering lost function through the regeneration of differentiated cells
Vgkc Encephalitis With Low-Titer Antibodies: Case Report
Authors:   Department of Neurology, Bakırköy Prof. Dr. Mazhar Osman Training and Research Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey, Aksoy Sena , Uzülmez Mina ,   Department of Neurology, Bakırköy Prof. Dr. Mazhar Osman Training and Research Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey, Soysal Aysun ,   Department of Neurology, Bakırköy Prof. Dr. Mazhar Osman Training and Research Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey
Published: January 2021

Voltage-gated potassium channel (VGKC) encephalitis is a type of autoimmune encephalitis, that presents with memory impairment, headache, psychiatric symptoms and seizures. Although contactin-associated protein 2 (CASPR2) and leucine-rich glioma inactivated 1 (LGI1) are clearly identifed as components of the VGKC complex, additional subtypes are known to exist. In this report, we present a case of 64-year-old patient with VGKC antibodies, negative for CASPR2 and LGI1
On The Shoulders of Giants Science Must Be Protected From Itself not Perceived and Not Realized Planetary Crime of the Century About Changing The Currently Dominant Paradigm The QuantumRelativistic Subconscious Building A General Theory of Physical Interactions by Solving Their Own Mechanical Models of Faraday and Maxwell
Authors:   Newton Society, Russia, Cherepennikov Vladislav
Published: January 2021

The monograph presents the evidence of outstanding thinkers - enlighteners of humanity and “great representatives of classical mechanics” about the failure and necessity of “changing the currently dominant paradigm” of the quantum-relativistic subconscious by solving their own mechanical models of Faraday and Maxwell – “the only conceivable guiding thread for the further successful development of modern physics”. Academician V. F. Mitkevich. “A Mature theory in which physical facts are explained mechanically will be constructed by those who, by questioning nature itself, will be able to find the only correct solution to the questions posed by mathematical theory.” James Clark Maxwell
Evaluation of Cellulose Nanoparticles Synthesized by Acid Hydrolysis for Safe Applications
Authors:   Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Norfolk State University, 700 Park Avenue, Norfolk, VA, 23504, USA, Tumkur Prathima Prabhu , Bayon Nicole Nazario ,   Center for Materials Research, Norfolk State University, 555 Park Avenue, Norfolk, VA, 23504, USA, Gunasekaran Nithin Krisshna ,   Center for Materials Research, Norfolk State University, 555 Park Avenue, Norfolk, VA, 23504, USA, Lamani Babu R ,   Department of Bioinformatics and Biotechnology, Akkamahadevi women’ s University, Jnanashakthi Campus, Vijayapura, Karnataka, 586 108, India, Prabhakaran Krishnan ,   Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Norfolk State University, 700 Park Avenue, Norfolk, VA, 23504, USA, Hall Joseph C ,   Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Norfolk State University, 700 Park Avenue, Norfolk, VA, 23504, USA, Ramesh Govindarajan T ,   Center for Materials Research, Norfolk State University, 555 Park Avenue, Norfolk, VA, 23504, USA
Published: January 2021

In the present study, cellulose nanoparticles were synthesized from waste cotton by acid hydrolysis method. Nanoparticles were obtained by the hydrolysis of pretreated cotton fibers with an acid mixture containing water, hydrochloric acid (HCl) and sulphuric acid (H2SO4). Characterization and biocompatibility studies of obtained cellulose nanoparticles were performed successfully. The morphological studies of cellulose nanoparticles were conducted by Field Emission Scanning Electron Microscopy (FESEM) and Transmission Electron Microscopy (TEM). Both showed that the cellulose nanoparticles synthesized from waste cotton measured approximately 100 - 200nm in diameter. Energy Dispersive X-ray Spectroscopic spectrum showed the elemental composition of the cellulose nanoparticles containing carbon and oxygen. Fourier Transform Infrared (FT-IR) spectroscopy spectrum revealed the presence of several characteristic peaks of cellulose nanoparticles. Human lung epithelial (Beas-2B) cells were used to assess the cytotoxicity and biocompatibility activity of cellulose nanoparticles. Cytotoxicity of cellulose nanoparticles was determined by 3-(4,5- Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay. Live/Dead viability assay was carried out to assess the biocompatibility of cellulose nanoparticles. Generation of Reactive Oxygen Species in Beas-2B cells incubated with cellulose nanoparticles was determined by Reactive Oxygen Species (ROS) assay. MTT and Live/Dead assays showed no significant induction of cell death even at higher concentrations (100 μg) upon exposure to Beas- 2B cells. ROS assay revealed that cellulose nanoparticles did not induce any reactive oxygen species that contribute to the oxidative stress and inflammation leading to various disease conditions. The results revealed that the cellulose nanoparticles have a great potential in a variety of commercial applications
Colon Screening In the Community–A Community Program and Lesson Learnt
Authors:   Faculty of medicine, University of Malaya, Kuala Lumpur, Malaysia, Yim Loh Siew
Published: January 2021

Colon-cancer awareness talk, with free faecal immunochemical (FIT) kit conducted by volunteers for the residents living near a cancer community centre in Petaling Jaya, an urban city with a multi-ethnic population. The aim of this report is to present and discuss the outcome of a community screening talk with free FIT kit. 295 healthy individuals who met inclusion criteria consented to take part in the pilot, only 62 percent (184/295) showed up for the intervention. 11.7 percent (n=19) were tested positives but only 9 went for a follow up colonoscopy, and the remainder were still waiting for a colonoscopy after 6 months. Cancer is still a fearful topic despite better treatment, and screening tests offered beneficial outcomes for early detection and cure, but the uptakes for the screening with awareness talk at a community centre on weekends is slow. Better study with outcome measures and qualitative study to explore barriers and facilitators are needed.
Pediatric Multisystem Inflammatory Syndrome Physiopathology and Covid-19
Authors:   CHLN-HSM-ImmunoAllergy- Lisbon (Portugal), Castro M Cortez e , M Bicho ,   Instituto Rocha Cabral-Lisbon (Portugal)
Published: January 2021

There are now more than 4 million confirmed cases of COVID-19, and more 285,000 deaths. The risk of severe disease and death has been highest in older people, and associated with age and one or more of the risk factors such as noncommunicable diseases (NCDs): hypertension, cardiovascular diseases, chronic lung diseases,kidney chronic disease, cancer and immunocompromised patients,or those exposed to high viral loads [1,2]. Children has more ACE2/ACE 2 receptors in mouth and nose and the elderly in the lungs, but there are also receptors in the kidney, endothelial cells and epithelial cells in the gastrointestinal tract,may be thatis why the symptomsdescribed in children were generally milder in children compared toadults, but some children do require hospitalization and intensive care [3], and now in Europe and USA there has been described a new syndrome that appears till 4 weeks after infection with SARSCoV-2-The Pediatric Multisystem Inflammatory Syndrome.