bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PENILAIAN KINERJA DAN PENGEMBANGAN KARIR TERHADAP MOTIVASI KERJA PADA PT TIRTA VARIA INTI PRATAMA
Authors: - SUWANTO -
Published: April 2022

ABSTRAK Tujuan dari penelitian ini adalah untuk menganalisis pengaruh positif dan signifikan penilaian prestasi kerja terhadap motivasi kerja, menganalisis pengaruh pengembangan karir terhadap motivasi kerja dan menganalisis pengaruh penilaian prestasi kerja dan pengembangan karir berpengaruh terhadap motivasi kerjaHasil pengujian pengaruh Penilaian prestasi kerja, pengembangan karir dan pengembangan karir secara bersama-sama terhadap motivasi kerja secara statistik menunjukkan hasil yang signifikan. Hal ini ditunjukkan oleh nilai Fhitung sebesar 35.622 dengan Ftabel adalah 2,69. Besarnya nilai Fhitung> Ftable mengindikasikan bahwa pengaruhnya signifikan. Dengan demikian hipotesis yang menyatakan bahwa pengaruh Penilaian prestasi kerja, Pengembangan karir dan pengembangan karir secara bersama-sama berpengaruh langsung dan signifikan terhadap motivasi kerja terbukti. Kata Kunci: Penilaian Kinerja, Pengembangan Karir dan Motivasi Kerja
PENGARUH GAYA KEPEMIMPINAN DAN DISIPLIN KERJA TERHADAP PRODUKTIVITAS KERJA KARYAWAN PT. CARAKA PILAR MANDIRI
Authors: Faruq Ubaid Al , El Fachmi Amin Kuneifi , Suherman Herry -
Published: April 2022

ABSTRACT The purpose of this research is to find out and analyze the influence of leadership styles and discipline work against employee productivity PT. Caraka Pilar Mandiri either by itself or together significantly, it also aims to find out the dominant variables against work productivity.This research is a research eksplanatori who try to test the hypothesis are statistically based on the empirical data from the respondents and explain it in descriptive and inferensial. The population of the research was an employee of PT. Caraka Pilar Mandiri totalling 102 people sampling method with saturated. Hypothesis testing is carried out by multiple linear regression analysis.Research results can be summed up as follows : (1) Acquired Fhitung of 26,989 with significance of 0.000. While the value of Ftabel on the level of confidence of 95% (α = 5%) was 3,088. That means that the leadership style (X1) and discipline work (X2) together influential very significantly to the productivity of employees at PT Caraka Pilar Mandiri. (2) Test results received a obtained the value of the coefficient of determination R2 of 0.353, which indicates that a variable work discipline and leadership style has the ability to explain its effects on employee productivity variable of 35.5% while the rest amounted to 64.5% is the influence of other free variables not examined in this study. (3) Test results between leadership style with work productivity are obtained coefficient determination (R2) of 0,196 which means that the free variables influence leadership style against the variable work productivity is of 19.6%. (4) Test results between the discipline of working with work productivity obtained coefficients of determination (R2) of 0.304 which means that the influence of the working discipline against the variable work productivity is of 34.7%. Keywords: Leadership Styles, Discipline, Productivity
ANALISIS PENGARUH KECERDASAN INTELEKTUAL, KECERDASAN EMOSI DAN KEPEMIMPINAN TERHADAP KINERJA KARYAWAN (Studi pada PT BANK BTN Cabang Ciputat)
Authors: EKA PRIEHADI DHASA
Published: April 2022

ABSTRAKSTujuan penelitian ini disebabkan penelitian-penelitian sebelumnya menunjukkan hasil yang berbeda-beda, sehingga perlu adanya penelitian yang kembali mengkaji tentang pengaruh kecerdasan intelektual, kecerdasan emosi dan kepemimpinan terhadap kinerja karyawan. Penelitian ini dilakukan di PT. BANK BTN Cabang Ciputat. Terdapat 100 responden yang telah dipilih sebagai sampel dengan menggunakan teknik pengambilan sampel berupa random sampling. Metode pengambilan data adalah dengan menggunakan kuesioner dan tes IQ. Teknik analisis data dalam penelitian ini adalah analisis regresi berganda. Peneliti menemukan bahwa seluruh hipotesis dalam penelitian ini telah terbukti secara signifikan. Kecerdasan intelektual, kecerdasan emosi dan kepemimpinan berpengaruh positif dan signifikan terhadap kinerja karyawan. Variabel yang memiliki pengaruh paling besar adalah kecerdasan emosi. Implikasi pada penelitian ini adalah kecerdasan intelektual, kecerdasan emosi dan kepemimpinan memiliki peran yang sama penting baik secara individu atau secara bersama-sama dalam meningkatkan kinerja karyawan.  Kata kunci: Kecerdasan Intelektual, Kecerdasan Emosi, Kepemimpinan dan Kinerja Karyawan
”Fun Phisycs” SEBAGAI SARANA PENDIDIKAN KARAKTER PADA ANAK USIA DINI
Authors: Solihat Ihat -
Published: April 2022

ABSTRAK Karakter lebih berkaitan dengan optimalisasi fungsi otak kanan. Mata pelajaran yang berkaitan dengan pendidikan karakter pun seperti budi pekerti dan agama ternyata pada prakteknya lebih menekankan pada aspek otak kiri (hafalan atau hanya sekedar “tahu”). Sedangkan, pembentukan karakter harus dilakukan secara sistematis dan berkesinambungan yang melibatkan aspek “knowledge, feeling, loving, dan acting”.Menurut Bronfenbrenner dalam teorinya tentang  family ecology and the child    development menyatakan bahwa anak merupakan suatu bagian dari sistem keluarga  yang  pertumbuhan dan perkembangannya mendapatkan pengaruh terutama dari keluarga kemudian dari lingkungan di luar keluarga, mulai dari lingkungan mikro, lingkungan messo, lingkungan exo dan lingkungan makro. Sehingga penyimpangan ataupun kebaikan yang terjadi pada individu  merupakan suatu hasil pengaruh sistem keluarga dan lingkungan luarnya. Untuk mengenal Tuhan melalui ayat-ayat alam yang terhampar yang kita huni beserta proses-proses alamiah didalamnya, dan untuk itu harus meneliti alam. Melalui serangkaian proses fisika yang ada yaitu mengukur apa yang diobsevasi, menganalisis data yang dihasilkan secara kritis  dan menarik kesimpulan yang rasional. Konsensus yang tercapai mengenai masalah-masalah alam yang timbul  merupakan materi yang terkandung dalam fisika (Achmad Baiquni:1997.17-22). Dengan ”Fun Physics” ini maka duharapkan dapat menjadikan anak-anak Indonesia yang berkarakter, unggul dalam bertindak dan cerdas dalam mengelola kehidupan., serta akan menjadi bertambah pengetahuan tentang fisika yang pada dasarnya ilmu fisika adalah ilmu tentang gejala alam yang mengandung banyak pel;ajaran untuk kehidupan.  Kata Kunci:”Fun Physics”, pendidikan karakter, usia dini
PENGARUH SUPERVISI, KEPEMIMPINAN PARTISIPATIF DAN KEPUASAN KERJA TERHADAP KUALITAS KERJA GURU SMA DI JAKARTA SELATAN
Authors: SURASNI SURASNI
Published: April 2022

ABSTRAK Penelitian ini bertujuan mengetahui pengaruh langsung dari variabel bebas seperti: Supervisi, Kepemimpinan Partisipatif dan Kepuasan Kerja terhadap variabel terikat yaitu Kualitas Kerja Guru. penelitian telah dilakukan pada guru SMA di Jakarta Selatan. Metode yang digunakan adalah survei dengan teknik analisis data menggunakan analisis jalur menggunakan SPSS Versi 18. Responden adalah sebanyak 100 dari 670 guru SMA di Jakarta Selatan yang dijadikan Populasi. Mereka dipilih secara random sampling. Hasil penelitian adalah sebagai berikut: (1) Supervisi berpengaruh langsung  positif terhadap Kualitas kerja, (2 Kepemimpinan Partisipatif berpengaruh langsung positif terhadap Kualitas Kerja, (3) supervisi berpengaruh langsung positif terhadap Kepuasan Kerja, (4) Kepemimpinan Partisipatif berpengaruh langsung positif terhadap Kualitas Kerja, (5) Kualitas Kerja  berpengaruh langsung positif terhadap Kualitas Kerja, dan (6).Supervisi  berpengaruh langsung positif terhadap Kepemimpinan Partisipatif. kesimpulannya adalah bahwa Kualitas kerja dipengaruhi oleh supervisi, Kepemimpinan Partisipatif dan Kualitas kerja guru. Kata Kunci: Kualitas kerja, Kepuasan kerja, Kepemimpinan partisipatif                       dan supervisi
ANALISA KEUNGGULAN POTENSI EKONOMI REGIONAL TANGERANG SELATAN
Authors: JUMINO JUMINO , MULYANTO EDI
Published: April 2022

Penelitian ini bermaksud untuk menganalisa dari keunggulan-keunggulan potensi ekonomi yang berada di Tangerang Selatan, sebagai kajian Ekonomi  Regional. Metode yang digunakan dalam penelitian ini yaitu menggunakan Location Quotient. Hasil penelitian menunjukkan bahwa di Kota Tangerang Selatan terdapat beberapa sektor basis (sektor potensial), yaitu  pada sektor pengadaan listrik dan gas, perdagangan besar dan eceran, reparasi mobil dan sepeda motor, transportasi dan pergudangan, jasa keuangan dan asuransi. Ke empat sektor basis tersebut menjadi sektor dominan untuk terus dapat dipertahankan dan dikembangkan di Kota Tangerang Selatan, oleh karena itu diharapkan Kota Tangerang Selatan dapat memberikan kontribusi meningkatkan pertumbuhan ekonomi baik secara regional maupun nasional.
Application Effect of Emergency Nursing Process in Elderly Patients with Acute Cerebral Infarction
Authors: Lu Yan
Published: April 2022

Objective — To explore the application effect of emergency nursing process in elderly patients with acute cerebral infarction. Methods — 206 elderly patients with acute cerebral infarction who received routine care in our hospital from January to December 2020 were selected as the control group, and 297 patients who received emergency nursing procedures from January to December 2021 were selected as the observation group. The treatment time, neurological function score, and living ability were compared between the two groups. Results — The triage time, referral time, and comprehensive treatment time of the observation group were shorter than those of the control group (P<0.05); the neurological function scores and daily living ability scores of the observation group were higher than those of the control group (P<0.05). Conclusion — The emergency nursing process can seize the best treatment time for elderly patients with acute cerebral infarction, improve the treatment effect and living ability, and is worthy of popularization and application.
A evolução dos sistemas gerenciais: do controle financeiro e orçamentário à administração estratégica
Authors: Pacheco Sabrina Rodrigues
Published: April 2022

O presente artigo almeja descrever os Sistemas Gerenciais (SG) a partir de perspectiva histórica, perfazendo um processo evolutivo que é concomitante com a consolidação gradual dos princípios da Administração Estratégica. Na primeira metade do século XX, a preocupação principal da nascente Administração de Empresas se voltava às questões de melhoria da eficiência na produção. A mentalidade dominante favorecia o “estilo incremental”, ou seja, pequenas melhorias eram preferidas às grandes mudanças ou rupturas. Entre 1900 e 1950, prevaleceu nas organizações o Controle Financeiro e Orçamentário, o mais antigo SG, que consistia no planejamento da produção com foco na lucratividade no curto prazo (1 ano). Na década de 1950, foi desenvolvido o Planejamento de Longo Prazo, que se baseava em um prognóstico de vendas para 5 anos. Na década de 1960, o aumento da competitividade e a redução da taxa de crescimento econômico forçaram a diversificação dos negócios e o foco da atenção para o ambiente externo. O conceito de estratégia é aplicado pela primeira vez com a criação das Unidades Estratégicas de Negócio (UENs). O Planejamento Estratégico Corporativo surgiria então na década de 1970, propondo uma nova divisão organizacional em três níveis: estratégico, tático e operacional. Nas décadas de 1980 e 1990, surge a Administração Estratégica, uma abordagem cuja principal inovação é a valorização do fator humano como determinante para o sucesso da estratégia. A questão norteadora é: qual a contribuição de cada SG para a Administração Estratégica? O objetivo geral é descrever a evolução histórica dos SGs, ressaltando os principais desenvolvimentos e os fatores limitantes que impuseram, em cada época, a necessidade de inovação. Quanto à metodologia da pesquisa, é de natureza bibliográfica e descritiva. Ao final desta investigação, concluiu-se que a Administração Estratégica como SG constitui o resultado de décadas de refinamento da prática da estratégia no ambiente organizacional, ainda que esse processo seja contínuo e seus avanços transitórios, considerando sempre a necessidade constante de aprendizado, adaptação e superação de desafios.
“Resenha: apontamentos sobre “O vice de ouro”, filme de Nícollas de Oliveira, documentando o Botafogo futebol clube de Ribeirão Preto de 2001, vice-campeão paulista”
Authors: Passos Rogério Duarte Fernandes dos
Published: April 2022

A resenha objetiva trazer apontamentos sobre o filme “O Vice de Ouro”, do cineasta Nícollas de Oliveira, que na película resgatou memórias da equipe de 2001 do Botafogo Futebol Clube de Ribeirão Preto, que surpreendeu no Campeonato Paulista de Futebol, alcançando o vice-campeonato.
Acciones de las empresas manufactureras exportadoras regionales, en transición hacia el ecomarketing
Authors: Muñoz Bautista Eduardo , Muñoz Rivera Rosa María
Published: April 2022

El relevante papel que está tomando la sustentabilidad en decisiones empresariales, por conciencia, responsabilidad o sensibilidad social, aunado al incremento del ecoconsumo, orienta el sondeo en empresas manufactureras exportadoras del estado de Hidalgo sobre la atención a iniciativas para transitar hacia una mercadotecnia ambiental, verde, sostenible o ecomarketing, desde la percepción de altos directivos y operativos. Las variables cuestionadas derivan de la gestión de riesgos ambientales y por ello la creación de valor para el consumidor y la sociedad. La investigación es cuantitativa, exploratoria, probabilística por área y cuotas, basada en dos constructos decisionales: ambiente y valor para la marca, significancia Chi2 en prueba de hipótesis y tablas de contingencia. Las percepciones entre directivos y operativos divergen en cuanto a instalación y uso de materiales ecológicos. Generalizando, 20% manifiesta realizar gestión ambiental, 45% lo intenta y 35% lo discrimina; y 35, 35 y 35% son los respectivos en creación de valor.
The relationship between supply chain management and competitiveness
Authors: Pinzón Castro Sandra Yesenia , Maldonado Guzmán Gonzalo , López Torres Gabriela Citlalli
Published: April 2022

The globalization of the markets and the new business environmental are forcing organizations, mainly the small and medium-sized enterprises, to improve their competitiveness significantly since to remain in the current market it is necessary to modify the managerial strategies to adapt them to the changes and the clients’ requirements. In this sense, supply chain management appears in the literature like one of the managerial strategies that are implementing in important number of firms to be able increase competitiveness.Therefore, the essential objective of this paper is to analyze the relationship between supply chain management and the competitiveness of small and mediumsized enterprises, using for it a sample of 305 firms of the Aguascalientes State. The obtained results show that supply chain management has a positive influence in competitiveness level, as well as in the financial performance, cost reduction and the use of technology of the small and medium-sized enterprises.
Competencias para la práctica docente
Authors: Badillo Gaona Manuela , Torres Rivera Alma Delia , Olea Deserti Elia
Published: April 2022

Se presenta un trabajo sobre la caracterización de las competencias docentes en el marco del modelo educativo del Instituto Politécnico Nacional (ipn). El objetivo consistió en “analizar la práctica educativa a través de la caracterización del docente de educación superior, a fin de establecer el perfil de competencias para la enseñanza”. Es un estudio de caso con enfoque mixto; se utilizó la entrevista y un cuestionario tipo Likert. El resultado fue una propuesta de intervención que proporciona al maestro los elementos teóricos y prácticos para su trabajo en el aula, cuya importancia es el aprendizaje de los alumnos a partir de la enseñanza de acuerdo con el modelo vigente en el ipn, institución que se encuentra a la vanguardia del contexto nacional actual, cuyas características se enmarcan en la economía del conocimiento como un elemento de oportunidad para convertirse en una institución con una ventaja competitiva ante la comunidad, los empresarios y el país.
Apathy, Antipathy and Settler Colonial Constructs of Environmental Justice: A Sentiment Analysis
Authors: Digout Amara
Published: April 2022

Within so-called Canada, settler colonialism exists as an ongoing structure of capitalism and dominance that contributes to land dispossession and, as such, informs the reproduction of environmental violence: a holistic form of violence that negatively affects Indigenous communities through a series of physical, spiritual, and emotional harms like that of the First Nations water crisis. This paper addresses commonly held sentiments towards the First Nations water crisis as they appear in social media comments on a recently posted video of Black and Indigenous activists at the International Climate Conference speaking to their lived experiences of environmental racism (CBC Canada, 2021). Million’s (2013) felt theory and notion of sociopolitical imaginaries are employed in this paper to guide the reframing of popular sentiments of apathy and antipathy that exist in the collective settler consciousness regarding environmental racism, the First Nations water crisis, and settler-colonial violence on Indigenous lands and bodies (as cited by Meissner, 2017). Further discussion is elicited on the relationship between local forms of environmental violence and the global climate crisis, with emphasis made towards reimagining the foci of international environmental stewardship movements as based on Indigenous ways of knowing and being.

This research paper was written, in part, as a contribution to the collaborative learning forum at X University titled Apathy to Empathy: Addressing the First Nations Water Crisis. Upon presenting this research at the event, an original creative piece was included, which maps the research presented in this paper and includes a collection of images related to the First Nations water crisis, settler colonialism, land degradation, and environmental advocacy (See Appendix).
Enseigner l'histoire 2.0 ? Chronique d'un long cheminement
Authors: Kaufmann Lyonel
Published: April 2022

En 2001, Larry Cuban publiait Oversold and Underused. Computers in the Classroom (Surestimés et sous-utilisés. Les ordinateurs en classe). En 2015, à la lecture de plusieurs enquêtes, la situation n’a guère évolué. S’il est un lieu où le numérique peine à faire sa place, c’est bien en classe. Le chemin paraît encore long avant de véritablement enseigner une histoire 2.0
Enseigner l'histoire : débats et controverses
Authors: Audigier François
Published: April 2022

Depuis que l’histoire a été introduite comme discipline scolaire dans une école devenue une institution essentielle dans la transmission intergénérationnelle, elle est l’objet de débats et de controverses souvent violents. L’année 2015, en Suisse romande ou en France, les a vus à nouveau rebondir : histoire nationale, histoire critique, chronologie, etc., sont des thèmes habituels. Cet article en reprend certains aspects et s’efforce de replacer cet enseignement dans le contexte réel des classes et de la transmission du passé chez les élèves, invitant ainsi à des débats mieux informés et plus utiles.
notrehistoire.ch, la plateforme de partage d'archives audiovisuelles de Suisse romande
Authors: Zurcher Claude
Published: April 2022

Lancée en 2009, notrehistoire.ch est à la fois une plateforme de valorisation des archives privées et institutionnelles et un réseau social réunissant des membres liés par un projet éditorial propre au domaine des archives. notrehistoire.ch favorise la conservation et l’utilisation des archives audiovisuelles. La plateforme permet au public d’être acteur de la construction d’une mémoire collective et soutient le partage de connaissance.
"Kalendaro", un atelier qui plonge les élèves dans le xxe siècle en remontant le fil des générations
Authors: Marendaz Colle Emmanuelle
Published: April 2022

Kalendaro est un atelier pédagogique sur les parcours de vie proposé aux classes romandes du secondaire. Il vise à transmettre aux élèves des notions utiles à la compréhension des inégalités sociales. L’approche se veut ludique, interdisciplinaire, et favorise les contacts intergénérationnels. Les jeunes apprennent à collecter des données biographiques réelles, puis à les analyser afin de mettre en évidence le poids du contexte historique et normatif dans lequel les personnes interrogées ont évolué.
La révolution industrielle à l'épreuve de l'histoire connectée
Authors: Etemad Bouda
Published: April 2022

This article is a story-connected exercise, illustrated by the English cotton industry, spearhead of the first Industrial Revolution. The development of this industry has been attributed sometimes to internal factors, other times to external factors. The exercice involves the broadest possible framework for analysis focusing on the relationship between these two factors.
La révolution industrielle à l’épreuve de l’histoire connectée. Le cas de l’industrie anglaise du coton
Authors: Etemad Bouda
Published: April 2022

This article is a story-connected exercise, illustrated by the English cotton industry, spearhead of the first Industrial Revolution. The development of this industry has been attributed sometimes to internal factors, other times to external factors. The exercise involves the broadest possible framework for analysis focusing on the relationship between these two factors.
L’appropriation des concepts de pouvoir, de hiérarchie sociale et de territoire en histoire et éducation à la citoyenneté chez des élèves du premier cycle du secondaire au Québec
Authors: Chiasson Desjardins Sandra , Bouvier Félix , Couture Pascale
Published: April 2022

This article is about the lessons learned by students from Québec in History and Citizenship Education (HCE). More specifically, the lessons linked to the concepts found in the HCE program are the subject of this study. It enables us to document the ownership of three recurring concepts from the program: territory, social hierarchy and power. The thematic analysis helps to draw a clear picture of the ownership of concepts in the form of topic trees.
Superiority of Admission Blood Urea Nitrogen over Serum Creatinine in Predicting In-Hospital Outcome of Patients with Acute Coronary Syndrome
Authors: Islam Md Saiful , Ara Mst. Ismot , Rahman Md HN Ashiqur , Ullah Mohammad , Rahman Md Mostafizur , Alam Md Sarwar , Shikder Mamunur Rashid , Kaiser Mohammad Abrar , Khan Md AKS Zahid Mahmud , Rahman Md Mojibur
Published: April 2022

Background: Serum creatinine and blood urea nitrogen (BUN) are the common markers of renal function and also one of the known predictors of adverse outcomes of acute coronary syndrome (ACS). The aim of this study is to assess the impact of elevated BUN on in-hospital outcome of ACS patients and superiority of BUN over creatinine for the assessment of in-hospital outcome in our setting.
Methods: This prospective observational study with purposive sampling of a total of 184 patients was conducted from October, 2009 to September, 2010. Based on normal cut off values (BUN and serum creatinine was <20 mg/dl and <1.4 mg/dl respectively) all the patients were divided into four groups; group I- both BUN and serum creatinine are normal, group-II- normal BUN and high serum creatinine, group-III- high BUN and normal serum creatinine, group-IV- - both BUN and serum creatinine are high. In-hospital data like hemodynamic conditions, heart failure, arrhythmias, conduction abnormalities, death etc. were noted. Assessment of in-hospital outcome of ACS patients and comparison to elevated serum creatinine and elevated BUN was done.
Results: ACS patients with only raised BUN level had more occurrence of cardiogenic shock (p=0.008), left ventricular failure (p=0.020), ventricular Tachycardia (p=0.022), ventricular fibrillation (P=0.037) and complete AV block (p=0.022) than those with only raised serum creatinine. In hospital mortality and hospital stay was also increased in ACS patients with elevated BUN than elevated serum creatinine (p value is 0.022 and 0.007 respectively).
Conclusion: Incidence of in-hospital death, cardiogenic shock, left ventricular failure, arrhythmia and duration of hospital stay were significantly (p<0.05) higher in patients who had raised BUN than raised serum creatinine. It is observed that elevated BUN is a better predictor of in-hospital outcome of ACS patients than elevated creatinine.
Cardiovasc j 2022; 14(2): 135-142
Relationship between QRS duration on Admission ECG and Angiographic Severity of Coronary Artery Disease in Patients with Acute Anterior Myocardial Infarction
Authors: Rahman Md Ataur , Ullah Mohammad , Hossain Md Iqbal , Ali Md Bonday , Kader Akanda Md Abdul
Published: April 2022

Background: Early risk stratification of patients with myocardial infarction is critical to determine optimum treatment strategies and improve outcomes. This study was designed to determine the relation between QRS duration on admission ECG and severity of coronary artery disease (CAD) in patients with acute anterior myocardial infarction (AMI).
Methods: This observational study was carried out from November 2019 to October 2020 with total of 100 patients with first attack of anterior MI who were treated with thrombolytic therapy. Based on the cut-off value of QRS duration 100, the patients were divided into two groups – one group with QRS duration £100 msec (normal QRS) and another group with QRS duration > 100 msec (prolonged QRS). Severity of CAD was assessed using Gensini score derived from coronary angiographic data. Gensini score < 36 points was regarded as mild coronary artery disease and Gensini score ³36 points as moderate to severe coronary artery disease. Then patients with prolonged and normal QRS durations were compared with severity of CAD to find their association.
Results: Acute AMI patients with prolonged QRS duration (> 100 msec) more often tend to be associated with severe CAD. Risk of having severe CAD in patients with prolonged QRS duration were almost 8 (95% of CI = 3.2– 19.3) times higher than those with normal QRS duration (£100 msec) (p < 0.001).
Conclusion: The study concluded that three out of four patients of acute anterior MI with prolonged QRS duration are likely to have severe CAD. QRS duration more than 100 msec can be used as a cheap, easily available prognostic factor in patients with acute anterior MI.
Cardiovasc j 2022; 14(2): 143-149
Patent Foramen Ovale and Cryptogenic Stroke : A Case Report
Authors: Fatema Nurun Nahar , Khan Ashfaque Ahammed
Published: April 2022

A 22 years old lady presented to emergency department of a private hospital with weakness and inability to move right side of the body along with aphasia, dizziness and headache since early morning. During process of evaluation and investigation she recovered spontaneously within few hours after conservative management. Magnetic resonance imaging of brain pre and post contrast along with MR angiography showed acute left parietal infarct. ECG excludes atrial fibrillation. Echocardiography later revealed tunnel shaped patent foramen ovale (PFO) with atrial septal aneurysm(ASA). Percutaneous closure of PFO was planned to prevent recurrence of stroke in this young lady.
Cardiovasc j 2022; 14(2): 180-184
Españolas, mestizas e indígenas de Huamanga en la Independencia peruana
Authors: Quichua David
Published: April 2022

Este artículo estudia el papel de las mujeres de Huamanga en la guerra por la independencia peruana. A través de documentos de archivos regionales y nacionales damos un sustento formal a la idea de que las mujeres contribuyeron significativamente cuando apoyaron a las fuerzas libertarias y realistas. Esta participación activa se traduce en sus aportes económicos y dirección de las actividades productivas con los cuales sustentaron la guerra; así también, permitieron la participación de sus familiares en las contiendas bélicas y difundieron los mensajes entre los actores de la contienda hasta el momento culminante del triunfo de Simón Bolívar en la batalla de Ayacucho (1824).
En la era del desgarramiento: Tensión y retransformación de la identidad cultural en los dominios de la globalización
Authors: Canaza-Choque Franklin Américo
Published: April 2022

Este estudio intenta realizar un breve recorrido hacia los impactos reproducidos por la globalización bajo los presupuestos imponderables de que esta resume ser, a efectos del ahora, una agencia inacabable que al interior y fuera de ella da cuenta de las fallas e irregularidades que se desprenden delimitando y tensando la noción de identidad cultural. De esta manera, a través de un recorrido de modelo teórico, puede definirse que el impacto globalizador provoca reconocer dos movimientos de réplica: por un lado, frente a impulsos homogeneizantes, la dimensión de interculturalidad para los reducidos grupos culturales precisa romper con la privilegiada divisoria entre lo global y lo local. Por el otro, en un espacio fracturado por problemas estructurales, donde el Estado parece desaparecer para algunos grupos minoritarios, el efecto irradia un desarme o desaparición parcial o total de estos últimos; lo cual, finalmente, termina provocando un desgarre en el denotativo de identidad cultural.
Grey seal Halichoerus grypus breeding sites contribute substantial carrion biomass to the Firth of Forth
Authors: Burns NM , Hopkins CR , Quaggiotto MM , McCafferty DJ , Bailey DM
Published: April 2022

Decomposing organic matter is central to the recycling of energy and nutrients in all ecosystems. Few studies have investigated the role of animal carrion biomass in ecosystem functioning, and quantitative data on carrion biomass are lacking. The role of carrion inputs in the marine environment specifically is poorly understood. The grey seal Halichoerus grypus breeding colony on the Isle of May in the Firth of Forth, Scotland, provides insight into the contribution of regular carrion pulses to the surrounding marine ecosystem. This study analysed 3 breeding locations with a range of topographies, elevations and tidal influences. Carcasses were mapped from aerial images and ground visual surveys in the 2008 and 2012 breeding seasons. Generalised linear mixed models were used to explore the degree to which breeding location and the position of a carcass influenced its availability to marine scavengers. Carcasses closer to shore were more likely to be completely displaced to the marine environment, and this effect varied with breeding location. An approximate 0.9 to 1.3 t of biomass per hectare of breeding site per year were released into the marine system. For carcasses that were below the high-water spring tide range but remained on shore, we quantified the typical duration of submersion to range from 5% to 44% of the time carcasses were ashore. Additionally, up to 808 kg of carrion was accessible to marine scavengers while washed by tides. Our results suggest breeding colonies of grey seals may contribute significantly to the carrion biomass available in local marine systems.
Preconditioning With Whole-Body or Regional Hyperthermia Attenuates Exercise-Induced Muscle Damage in Rodents
Authors: MIKAMI T , YAMAUCHI H
Published: April 2022

Our aim was to investigate whether hyperthermia before exercise protects against exercise-induced skeletal muscle damage. Two hyperthermia protocols were evaluated. In the first, male ICR mice were exposed to 30 min of whole-body heat in an environmental chamber at an ambient temperature of 42 °C. Heat-exposed and non-heat-exposed mice subsequently completed 60 min of downhill running on a treadmill, 24 h after exposure. Heat exposure significantly increased HSP70 and HSP25 content in the soleus muscle compared to controls. Plasma creatine kinase, muscle β-glucuronidase, and histochemical (hematoxylin and eosin stain) analysis demonstrated that muscle damage was lower in the heat-exposed mice than in the non-heat-exposed mice. In the second, the effect of regional heating of the legs, by microwave diathermy, on the prevention of exercise-induced muscle damage was evaluated in male Wistar rats. Microwave-treated and non-microwave-treated rats again completed the running protocol 24 h after exposure. Microwave diathermy increased the muscle temperature to 40 °C, significantly increased HSP70 and HSP25 content in the soleus muscle, and significantly attenuated exercise-induced muscle damage. Therefore, hyperthermia before exercise increases skeletal muscle HSPs and attenuates the risk of exercise-induced muscle injury.
Performance of Non-Cementitious Repair Materials for Concrete Pavement Partial-Depth Repairs in Wisconsin
Authors: Ram Prashant , Smith Kurt , Shah Ayesha , Olek Jan , Kang Myungook
Published: April 2022

The Wisconsin Department of Transportation (WisDOT) is continually looking for state-of the-art technologies, materials, and methodologies to cost-effectively preserve the condition of their pavements so as to extend the service life and delay the need for major rehabilitation or reconstruction. In a search for a more durable and sustainable concrete pavement repair strategy, WisDOT has used non-cementitious materials for partial-depth repairs (PDR) on concrete pavements but with varying levels of success. Where poor performance from these repairs has been observed, it has been attributed to either poor workmanship or inappropriate use of the repair material for the prevailing conditions. These factors suggest that the non-cementitious materials may have been used as a “band-aid” fix to allow for early opening to traffic rather than selected and implemented as the most suitable repair strategy to effectively address the specific distresses in the existing pavement. This paper presents a summary of an investigation into the use of non-cementitious repair materials for concrete pavement PDR applications. A field survey of five different non-cementitious repair materials used in PDR applications throughout Wisconsin was performed and the results documented. Additionally, the findings from a limited laboratory testing program conducted to assess the bond and dimensional stability properties of three non-cementitious materials at different testing temperatures are also presented. The paper concludes with guidance on the use of non-cementitious repair materials for concrete pavement PDR applications in Wisconsin.
Numerical Simulation of Flame Combustion Characteristics of Tail Gas From the Copper Slag Depleted Reduction
Authors: Sun Huiping , Xie Haojie , Luo Siyi , Zhang Weiwei , Zuo Zongliang , Xianjun Guo
Published: April 2022

The tail gas with relatively high calorific value, generated from the depleted reduction of copper slag, can be used as fuel for gas turbines. In this study, the flame speed calculation module in PREMIX of CHEMKIN was used to simulate the combustion characteristics of the tail gas after sulfide removal, the effects of equivalence ratio, gas preheating temperature, and the CO2 concentration on the flame propagation speed and the flame combustion temperature were mainly investigated. Results show that the flame propagation speed and the flame combustion temperature increase continuously with the increase in preheating temperature, while it decreases continuously with the increase in CO2 concentration. Additionally, the peak flame combustion temperature appears at an equivalent ratio of 1.1, while the peak flame propagation speed appears at an equivalent ratio of 2.0, which indicates that the flame combustion temperature is not the main factor affecting flame propagation speed for tail gas.
Genotyping-by-Sequencing Based Molecular Genetic Diversity of Pakistani Bread Wheat (Triticum aestivum L.) Accessions
Authors: Hussain Shabbir , Habib Madiha , Ahmed Zaheer , Sadia Bushra , Bernardo Amy , Amand Paul St. , Bai Guihua , Ghori Nida , Khan Azeem I. , Awan Faisal S. , Maqbool Rizwana
Published: April 2022

Spring wheat (Triticum aestivum L.) is one of the most imperative staple food crops, with an annual production of 765 million tons globally to feed ∼40% world population. Genetic diversity in available germplasm is crucial for sustainable wheat improvement to ensure global food security. A diversity panel of 184 Pakistani wheat accessions was genotyped using 123,596 high-quality single nucleotide polymorphism (SNP) markers generated by genotyping-by-sequencing with 42% of the SNPs mapped on B, 36% on A, and 22% on D sub-genomes of wheat. Chromosome 2B contains the most SNPs (9,126), whereas 4D has the least (2,660) markers. The mean polymorphic information content, genetic diversity, and major allele frequency of the population were 0.157, 0.1844, and 0.87, respectively. Analysis of molecular variance revealed a higher genetic diversity (80%) within the sub-population than among the sub-populations (20%). The genome-wide linkage disequilibrium was 0.34 Mbp for the whole wheat genome. Among the three subgenomes, A has the highest LD decay value (0.29 Mbp), followed by B (0.2 Mbp) and D (0.07 Mbp) genomes, respectively. The results of population structure, principal coordinate analysis, phylogenetic tree, and kinship analysis also divided the whole population into three clusters comprising 31, 33, and 120 accessions in group 1, group 2, and group 3, respectively. All groups were dominated by the local wheat accessions. Estimation of genetic diversity will be a baseline for the selection of breeding parents for mutations and the genome-wide association and marker-assisted selection studies.
Formation, Transmission, and Dynamic Evolution of a Multidrug-Resistant Chromosomally Integrated Plasmid in Salmonella Spp.
Authors: Chang Man-Xia , Zhang Jing , Zhang Jin-Fei , Ding Xiao-Min , Lu Yang , Zhang Jie , Li Ruichao , Jiang Hong-Xia
Published: April 2022

IncHI2 plasmids, possessing high flexibility and genetic plasticity, play a vital role in the acquisition and transmission of resistance determinants. Polymorphic mobile genetic elements (MGEs) generated by a chromosomally integrated IncHI2 plasmid in an individual Salmonella isolate have not yet been detected, and the mechanisms of the formation, excision, and dynamic evolution of a multidrug-resistant chromosomally integrated plasmid (MRCP) have remained obscure. Herein, we identified a 260-kb blaCTX–M–55-qnrS1-bearing IncHI2 plasmid within a Salmonella Muenster strain. Plenty of heterogeneous MGEs (new Escherichia coli chromosomally integrated plasmid or circular plasmids with different profiles) were yielded when this MRCP was conjugated into E. coli J53 with a transfer frequency of 10–4–10–5 transconjugants per donor. A bioinformatic analysis indicated that replicative transposition and homologous recombination of IS26 elements were particularly active, and the truncated Tn1721 also played a vital role in the formation of MRCP offspring. More importantly, when released from the chromosome, MRCP could capture and co-transfer adjacent chromosomal segments to form larger plasmid progeny than itself. Stability and growth kinetics assays showed that the biological characteristics of MRCP progeny were differentiated. This study provides an insight into a flexible existence of MRCP. The conversion between vertical and horizontal transmission endowed MRCP with genetic stability as a chromosomal coding structure and transferability as extra-chromosomal elements. This alternation may accelerate the acquisition and persistence of antibiotic resistance of clinical pathogens and enhance their ability to respond to adverse environments, which poses a great challenge to the traditional antibiotic treatment.
The Plasma Level of Interleukin-1β Can Be a Biomarker of Angiopathy in Systemic Chronic Active Epstein–Barr Virus Infection
Authors: Ohashi Ayaka , Uemura Yu , Yoshimori Mayumi , Wada Naomi , Imadome Ken-Ichi , Yudo Kazuo , Koyama Takatoshi , Shimizu Norio , Nishio Miwako , Arai Ayako
Published: April 2022

Systemic chronic active Epstein–Barr virus infection (sCAEBV) is an EBV-positive T- or NK-cell neoplasm revealing persistent systemic inflammation. Twenty-five percent of sCAEBV patients accompany angiopathy. It is crucial to clarify the mechanisms of angiopathy development in sCAEBV because angiopathy is one of the main causes of death. Interleukin-1β (IL-1β) is reported to be involved in angiopathy onset. We investigated if IL-1β plays a role as the inducer of angiopathy of sCAEBV. We detected elevated IL-1β levels in four out of 17 sCAEBV patient’s plasma. Interestingly, three out of the four had clinically associated angiopathy. None of the other patients with undetectable level of IL-1β had angiopathy. In all patients with high plasma levels of IL-1β and vascular lesions, EBV-infected cells were CD4-positive T cells. In one patient with high plasma IL-1β, the level of IL-1β mRNA of the monocytes was 17.2 times higher than the level of the same patient’s EBV-infected cells in peripheral blood. In Ea.hy926 cells, which are the models of vascular endothelial cells, IL-1β inhibited the proliferation and induced the surface coagulation activity. IL-1β is a potent biomarker and a potent therapeutic target to treat sCAEBV accompanying angiopathy.
Molecular Network of Colorectal Cancer and Current Therapeutic Options
Authors: Huang Zhe , Yang Mingli
Published: April 2022

Colorectal cancer (CRC), a leading cause of cancer-related mortalities globally, results from the accumulation of multiple genetic and epigenetic alterations in the normal colonic and rectum epithelium, leading to the progression from colorectal adenomas to invasive carcinomas. Almost half of CRC patients will develop metastases in the course of the disease and most patients with metastatic CRC are incurable. Particularly, the 5-year survival rate of patients with stage 4 CRC at diagnosis is less than 10%. Although genetic understanding of these CRC tumors and paired metastases has led to major advances in elucidating early driver genes responsible for carcinogenesis and metastasis, the pathophysiological contribution of transcriptional and epigenetic aberrations in this malignancy which influence many central signaling pathways have attracted attention recently. Therefore, treatments that could affect several different molecular pathways may have pivotal implications for their efficacy. In this review, we summarize our current knowledge on the molecular network of CRC, including cellular signaling pathways, CRC microenvironment modulation, epigenetic changes, and CRC biomarkers for diagnosis and predictive/prognostic use. We also provide an overview of opportunities for the treatment and prevention strategies in this field.
Super-Minimal Incision Technique in Pediatric Kidney Transplantation: A Paired Kidney Analysis
Authors: Wang Junxiang , Zhao Lixiang , Feng Guiwen , Shang Wenjun
Published: April 2022

Background

Recently, the demand for minimally invasive techniques in kidney transplantation (MIKT) has increased. However, there is only a limited number of studies on MIKT, especially in pediatric kidney transplants. Hence, we evaluated whether there is a difference between the super-minimal incision technique in pediatric kidney transplantation (SMIPKT) and conventional kidney transplantation (CKT).

Methods

Between December 2018 and November 2021, 34 patients who underwent pediatric kidney transplantation with a follow-up of 1 month were enrolled. A paired kidney analysis was performed to minimize donor variability and bias. The SMIPKT and CKT groups included 17 patients.

Results

There was no difference in baseline clinical characteristics, including age, sex, the donor/ recipient weight ratio (DRWR), choice of dialysis modality, pretransplant dialysis time, BMI, renal artery number, cause of ESRD, DGF, length of the kidney and cold ischemic time, tacrolimus concentration at 3 and 7 days, serum creatinine at 1 month and postoperative complication rate between the SMIPKT and CKT groups (all P > 0.05). However, the length of the incision, operation time, intraoperative bleeding, postoperative drainage volume within 24 h and Vancouver scar scale at 1 month were statistically significant (all P < 0.05).

Conclusion

Compared with CKT, our results indicated that SMIPKT showed more satisfactory cosmetic results, shorter SMIPKT operating time, and reduced intraoperative bleeding and postoperative drainage volume within 24 h. There were also no statistical differences in postoperative complications. Hence, we suggest that SMIPKT is an appropriate method for pediatric kidney transplantation.
An Analysis on the Factors for Cervical Insufficiency Causing Adverse Emotions Among Pregnant Women at Different Gestation Phases
Authors: Wu Qichang , Chen Jiebing , Zou Qiaojian , Zeng Xun , Yang Yan , Zhou Yijia , He Guimei , Luo Chunqi , Wu Fengchun
Published: April 2022

Background

To analyze the anxiety, depression, and related factors among pregnant women with cervical insufficiency, so as to provide a reference for clinical psychological intervention as an adjuvant therapy.

Methods

A total of 101 cases in China with cervical insufficiency were included in the observation group by a convenience sampling method, and 114 normal healthy women of childbearing age were selected as the control group. Participants were investigated and observed for anxiety and depression by SAS and SDS, respectively, to analyze the emotional state and influencing factors of the patients with cervical insufficiency. Stratified by the first, second and third trimesters, our study used whether depressive or not and whether anxiety or not as the dichotomous variables. A multivariate Logistic regression was adopted to analyze the influencing factors. Relevant influencing factors were screened out by the forward stepwise method in combination with professional knowledge and the number of variables.

Results

There were statistical significant differences in SAS and SDS between observation group and control group and the incidence rate of anxiety and depression was higher in pregnant women with CI. Multivariate Logistic regression demonstrated that history of abnormal pregnancy was the main influencing factor for anxiety and depression in the early and middle gestation phases, and cervical insufficiency was the factor influencing the anxiety in early gestation and both anxiety and depression in the late gestation phase.

Conclusion

Cervical insufficiency may have a negative impact on the emotions of pregnant women. Individualized and targeted mental care should be added into clinic work to prevent negative outcomes.
Exploring the Nursing Factors Related to Ventilator-Associated Pneumonia in the Intensive Care Unit
Authors: Yin Yanling , Sun Meirong , Li Zhe , Bu Jingjing , Chen Yuhong , Zhang Kun , Hu Zhenjie
Published: April 2022

Objective

The purpose of this study was to investigate the key nursing factors associated with ventilator-associated pneumonia (VAP) in critical care patients.

Methods

Through the quality control platform of Hebei Province, questionnaires were sent to intensive care nurses in 32 tertiary hospitals in Hebei Province, China to collect data concerning the incidence of VAP and the status of the nursing staff. All the data were analyzed using an independent t-test and a one-way analysis of variance (ANOVA). The Pearson correlation coefficient was used to analyse the correlation between the nursing factors and the incidence of VAP. Multivariate logistic regression analysis was used to determine the risk factors affecting VAP.

Results

In terms of nursing, the incidence of VAP was affected by the differential nursing strategies. Multivariate logistic regression analysis showed that the incidence of VAP was significantly associated with the following six variables: the ratio of nurses to beds (p = 0.000), the ratio of nurses with a bachelor's degree or higher (p = 0.000), the ratio of specialist nurses (p = 0.000), the proportion of nurses with work experience of 5–10 years (p = 0.04), the number of patients nurses were responsible for at night (p = 0.01) and the frequency of oral care (p = 0.000).

Conclusion

The incidence of VAP is closely related to nursing factors. In terms of nursing human resources, even junior nurses (less experienced nurses) can play an essential role in reducing VAP. In addition, to reduce VAP, the number of patients that nurses are responsible for at night should be reduced as much as possible, and improving nursing qualifications.