bluuebunny/crossref_metadata_2025 huggingface dataset:
Provincial and District Zemstvos of the Ufa Province: Practices of Interaction in the Field of Personnel Policy in the Late XIX – Early XX Century
Authors:   Ufa University of Science and Technology, Polyanina Olga A.
Published: April 2024

The article analyzes practices of interaction between provincial and district zemstvos of the Ufa province with regard to personnel policy. Depending on the source of salary payment, zemstvo employees were divided into two categories: district and provincial. All personnel decisions concerning zemstvo employees were made by the local self-government bodies of the relevant district. The analysis of the correspondence of the Ufa zemstvo boards allows to assert that the attempts of the provincial zemstvo to influence the invitation or relocation of district employees were not successful. The districts autonomy increased the flexibility of the zemstvo personnel policy, but prevented establishing the social security system for employees. Certain staff categories (veterinarians, agronomists, technicians, insurance agents) received salaries from the provincial tax charges and, accordingly, were subordinate to the provincial zemstvo. At the same time, the professional responsibilities of such employees were related to a particular district. As a result, at the early XX century, the Ufa provincial zemstvo delegated part of its personnel powers to the district level.
The Link Between Executive Functions and Spelling (French vs Arabic) in Bilingual Children from Grade 2 to Grade 4, for a Better Rehabilitation of Specific Learning Disorders
Authors:   Speech and Language Therapy Department, Private Care Clinic, Beirut, Lebanon, Kechichian Khanji Anna
Published: April 2024

Challenged with the peculiarities of school learning in Lebanon and the orthographic complexities specific to French and Arabic, children face conditions requiring additional cognitive effort. Our objective is to study the link between executive functions (EF) (inhibition, working memory (WM), flexibility and planning) and spelling, in 180 bilingual children with typical development (TD) and with specific learning disorders (SLD), in Grades 2, 3, and 4. EF were assessed through the following tests: Image matching, Corsi, Numbers Backward, Opposite worlds, Categorization (Animal sorting), and LABY 5-12 tests. Spelling was assessed in both languages through sentence dictation. Our results show that all EF are more involved in Arabic than in French, being correlated with accuracy and speed of spelling in the entire population. This study clarifies the cognitive components underlying French and Arabic spelling, which are languages with many unique features, for better management of written language disorders.
Can Popular Word Search Puzzles Affect Walking Speed in Older Adults?
Authors:   Department of Psychology, Faculty of Arts, Masaryk University, Brno, Czech Republic, Vajda Petr , Strašilová Kateřina ,   Faculty of Sports Studies, Masaryk University, Brno, Czech Republic, Svobodová Lenka ,   Faculty of Sports Studies, Masaryk University, Brno, Czech Republic, Hlinský Tomáš ,   Faculty of Sports Studies, Masaryk University, Brno, Czech Republic
Published: April 2024

We examined whether supraliminal word stimuli can affect walking speed of older adults in laboratory settings. The 78 physically active subjects (age >65 years) were randomly assigned to prime and control conditions. All subjects walked 19 m measured distance pre- and post-completing a word search puzzle containing either words associated with early adulthood or neutral ones. Although participants in the prime group went faster in the posttest, the ANOVA did not reveal significant interaction between the subjects’ conditions and walking speed. No significant priming effect of exposure to words on walking speed in older adults was detected in the current study. There is a need for further research, as there is a lack of data in this age cohort. The priming effect could possibly be used to increase the physical activity of seniors and may bias the clinical outputs in gait tests.
Reasons For Exercise and Training-Induced Affective Changes in Co-active and Interactive Sports
Authors:   Institute of Health Promotion and Sport Sciences, ELTE Eötvös Loránd University, Budapest, Hungary; Doctoral School of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary, Ábel Krisztina E. , Komáromi Liza ,   Hungarian University of Sports Science, Budapest, Hungary, Szabo Attila ,   Institute of Health Promotion and Sport Sciences, ELTE Eötvös Loránd University, Budapest, Hungary
Published: April 2024

Generally, in interactive sports, one focuses on performance-related field events, cooperation, and coordination rather than subjective feelings. Therefore, we hypothesized that subjectively perceived positive affect would rise immediately after co-active but not interactive exercise training. We used the Exercise-Induced Feeling Inventory (EFI) to test positive engagement, revitalization, tranquility, and physical exhaustion pre- and post-training in 107, primarily male, university students practicing either co-active (aerobic exercise, martial arts, swimming; N =54) or interactive (basketball, soccer, football; N=53) sports. We also assessed their enthusiasm before training and perceived exertion after training. Training-induced affective changes in the dependent measures were expressed as percentage change scores and subjected to multivariate covariance analyses. The results did not support our hypothesis that co-active exercisers experience more positive affective states due to training than interactive exercisers. However, co-active exercisers reported more enthusiasm before training and greater physical exhaustion after the training than interactive exercisers. There was also a statistically non-significant trend in the ratios of the reasons for exercise participation, with more than two-thirds of co-active exercisers training for health reasons compared to less than half of interactive exercisers who participated more for mastery and enjoyment reasons. These results suggest that affective states following a single exercise bout do not differ between co-active and interactive exercisers. However, enthusiasm differences between these forms of sports could be related to self-centered, attentional-focused training, health-related motivation, and more exhaustive training.
RECENSIÓN DE Governação Fiscal Global. PAULA DOURADO, A., Ed. Almedina, Coimbra. 2023. 414 pp.
Authors: Coronas Valle Daniel
Published: April 2024

Este trabajo comenta la obra de la catedrática e investigadora portuguesa Ana Paula Dourado, que aborda los grandes retos de la fiscalidad internacional del último quinquenio. Profunda conocedora del marco europeo, desglosa el presente al tiempo que atisba el futuro de regulacion tan criticas y necesarias para luchar contra el fraude fiscal internacional como la iniciativa BEPS. Completamos su análisis con una revisión de las novedades del marco tributario español, especialmente aquellas que transponen  ciertas normativas de la UE.
El régimen financiero y tributario de la pensión unificada en la Unión Europea
Authors: Aguilar Segado Carlos David
Published: April 2024

Europa se encuentra actualmente en una situación de envejecimiento debido a que la población mayor de 65 años supera los 100 millones de personas. Las reformas de las pensiones abordan la reducción del gasto y la dependencia de las personas mayores. Existen diversos modelos de pensiones en Europa, desde el "bismarckiano" hasta el "multipilar". Las medidas presupuestarias, impulsadas por la competencia económica y los requisitos de la Unión Europea, buscan limitar el gasto en pensiones. La oposición a las reformas varía entre países, influida por factores sociales y sindicales.

La solidaridad intergeneracional es crucial, ya que recortes en pensiones pueden afectar tanto a mayores como a jóvenes. La Unión Europea busca unificar las pensiones para aquellos que han trabajado en varios Estados Miembros y llevar a cabo el procedimiento para solicitar la pensión unificada teniendo en cuenta las edades de jubilación, los periodos cotizados y el régimen financiero y tributario de cada país. Sin embargo, la imposición de reformas supone la resistencia de algunos Estados europeos a las mismas. La cuestión fiscal, las tasas de pobreza en personas mayores, la necesidad de equilibrar la sostenibilidad económica y la justicia social son desafíos centrales en la cuestión sobre el sistema de pensiones europeo.
Analysis of the contents of Ugni molinae Turcz fruits across the ripening stages
Authors: Cortiella Mariona Gil i , Castro Ricardo I. , Parra-Palma Carolina , Méndez-Yáñez Angela , Ramos Patricio , Morales-Quintana Luis
Published: April 2024

Recently, a growing interest in fruits having a high content of health-promoting compounds has become a trend among consumers around the world. Wild berries have received special attention based on the high levels of healthy compounds present in them. In this work, we elaborate on the qualities of the murta (Ugni molinae Turcz) fruit such as the colour, the volatile organic compounds (VOCs) present, its antioxidant capacity and the phenolic compound content (including those of flavonols and anthocyanins) with respect to the different ripening stages. Four stages were established based on the skin colour parameters, which were consistent with the changes in the weight and size of the murta fruits. In addition, the total phenolic and flavonols content showed a decrease during fruit ripening, in contrast with the total anthocyanins content that increased at the final stages of ripening. Additionally, the antioxidant capacity was evaluated via two approaches: ferric reducing antioxidant power and 1,1-diphenyl-2-picrylhydrazyl discolouration assay; higher levels of antioxidants at the final stages were consistently observed. Furthermore, the VOCs profile showed terpenoids to be the main compounds, with the highest relative abundances in fully ripe fruits. These results allow us to propose a classification of the different ripening stages of the murta fruits. This would enable us to have better knowledge of this interesting fruit, which possesses highly healthy nutraceutical compounds.
MANAGEMENT OF MEGACOLON CASES IN CATS WITH THE ADDITION OF YELLOW PUMPKIN TO THEIR FEED: A CASE REPORT
Authors: Pradipta I Putu Indra Manik , Jayanti Putu Devi , Soma I Gede , Gunawan I Wayan Nico Fajar
Published: April 2024

Megacolon is a pathological condition associated with failure to defecate normally, most commonly diagnosed in cats. The medical management of megacolon has not been widely reported, hence the importance of writing this article. This case study is about a 2-year-old male Angora cat who was observed to have difficulty in defecating since 3 weeks. Clinical examination revealed normal borborygmus sounds and a solid abdominal consistency suspected to be fecal accumulation. Hematology examination was performed and the result showed Neutrophilia. Radiological examination showed accumulation of hardened feces in the colon. Based on the history, clinical examination, and supporting examination, the animal had megacolon with a prognosis of fausta. The cat was given lactulose and a feed mixture of wet food and pumpkin supplement. Results from laxative therapy with pumpkin supplementation for seven days showed the cat's fecal consistency FCS 3.5. The owner is advised to change the cat's feed to wet food with pumpkin added, as well as perform physical exercise on the cat.
THE RELATIONSHIP BETWEEN BIOSECURITY IMPLEMENTATION AND MORBIDITY AND MORTALITY IN PIGS IN PAYANGAN DISTRICT, GIANYAR BALI
Authors: Pitaloka Ni Made Wida Rieke , Suada I Ketut
Published: April 2024

Until now, pig farming in Bali has a very important role in supporting the economy of the local community. However, the management of pig farms in Bali cannot be separated from the obstacles faced, namely the outbreak of disease agents. Biosecurity is considered a fundamental cornerstone of all disease control programs. The aim of this research is to determine the relationship between the application of biosecurity and morbidity and mortality. This research uses an observational design. The number of respondents used in this research was 40 breeders. Data collection in this research was carried out by conducting surveys and interviews with farmers regarding the implementation of biosecurity and the incidence of morbidity and mortality on the farms they own. The data obtained is presented in tabular form. Chi-square test analysis was carried out to compare data from farms that implemented biosecurity with those that did not implement biosecurity. The research results found that farms that implemented biosecurity experienced 6 incidents of morbidity and 3 incidents of mortality. Meanwhile, farms that did not implement it experienced 15 morbidity incidents and 11 mortality incidents. The conclusion of this research is that implementing biosecurity on a farm can reduce the incidence of morbidity and mortality. The advice that can be given is that preventive efforts such as implementing biosecurity should not only be carried out if a case has occurred but must continue to be carried out on an ongoing basis.
HISTOPATHOLOGICAL PICTURE OF WHITE RATS HEART POST APPLICATION OF MIMOSIN FROM SIMPLISIA LAMTORO LEAF
Authors: Suastami Ni Made Ayu , Berata I Ketut , Setiasih Ni Luh Eka , Samsuri  , Sudimartini Luh Made , Suatha I Ketut
Published: April 2024

Mimosine is a toxic compound that can be found in the leaves of the lamtoro plant (Leucaena leucocephala). Toxicity that occurs in livestock depends on the concentration of mimosine in the feed and the length of time it is administered. This study aims to determine the histopathological picture of the heart of white rats (Rattus norvegicus) given mimosine from lamtoro leaf simplicia at different doses. The research used 2 months old Wistar male white rats weighing 300-350 grams. The 20 experimental animals used were divided into 4 treatment groups, namely P0 (negative control) without mimosine, P1 (positive control) given standard mimosine 5 mg/head/day, P2 given lamtoro leaf simplicia at a dose of 50 mg/head/day, and P3 simplicia lamtoro leaves at a dose of 150 mg/head/day. Mimosine was given orally for 14 days using a probe. On the 15th day, a necropsy was performed, the heart organ was removed and placed in 10% NBF. Next, it is processed to make histopathological preparations with HE staining. Histopathological examination was carried out including three variables: congestion, bleeding and necrosis. The severity of the lesion was scored, namely 0, 1, 2, and 3 respectively for normal, mild, moderate, and severe lesions. The data was then analyzed using the non-parametric Kruskal-Wallis and Mann-Whitney tests. The results of the study showed that administration of mimosine from lamtoro leaf simplicia could cause histopathology in the form of congestion, bleeding and necrosis lesions compared to controls and there was no effect on the difference in the dose of mimosine from lamtoro leaf simplicia between doses of 50 mg/head/day and 150 mg/head/day.
THE KNOWLEDGE LEVEL OF FARMERS OF BIOSECURITY POST OF FOOT AND MOUTH DISEASE EPIDEMIC IN MEDAHAN VILLAGE, BLAHBATUH DISTRICT, GIANYAR REGENCY, BALI
Authors: Brahmantika I Made Adi , Tenaya I Wayan Masa , Suartini I Gusti Ayu Agung , Mufa Romy Muhammad Dary
Published: April 2024

Foot and mouth disease (FMD) is an infectious disease caused by viruses of the genus Aphthovirus and prevention can be done by applying biosecurity principles. Biosecurity has three important components, namely isolation, traffic control and sanitation. This research aims to determine the level of knowledge of farmers regarding biosecurity after the FMD outbreak in Medahan Village, Blahbatuh District, Gianyar Regency. The design of this research was observational by interviewing 54 cattle and pig farmers conducted from November to December 2023 using a questionnaire containing 20 questions. The data obtained was then analyzed descriptively quantitatively and presented in the form of tables/diagrams. To determine the relationship between age, breeder's main occupation, education, and number of livestock with the breeder's level of knowledge, Chi-Square analysis was carried out using SPSS version 25 for Windows. The research results showed that breeders in Medahan Village had a good level of knowledge on sanitation competence, sufficient knowledge on isolation competence, and poor knowledge on traffic control competence. These results are influenced by educational factors, the farmer's main job, and the number of livestock. The conclusion of this research is that in general breeders in Medahan Village have a low level of knowledge regarding biosecurity after the FMD outbreak. A socialization program regarding biosecurity principles that is more targeted and reaches the target of FMD-vulnerable animal breeders needs to be carried out to re-emerge FMD outbreaks.
A STRUCTURE AND HISTOMORPHOMETRY OF BALI DUCK TESTES IN THE GROWER PHASE
Authors: Adiari Ni Made Santi Rahayu , Setiasih Ni Luh Eka , Sampurna I Putu , Suwiti Ni Ketut , Susari Ni Nyoman Werdi , Suatha I Ketut
Published: April 2024

Testes are male reproductive organs which are responsible for producing spermatozoa and steroid hormones. This study aims to determine the histology and histomorphometry structure of bali duck testes in the grower phase at the age of 12 weeks in one of the farms in Mengwi District, Badung Regency. The number of samples used in this research was 10 male bali ducks that were in good health. There are two examination methods carried out, namely the qualitative descriptive anatomical structure and histology examination method and the quantitative histomorphometry examination method of bali duck testicles which are analyzed using the One-Sample T-test with a confidence level of 95%. The results of this study show the anatomical structure of the bali duck testicles which are located in the abdominal cavity, between the kidneys and the lungs. The pair of testicles have the shape of a bean and are cream colored. The results of research on the histological structure of bali duck testes consist of seminiferous tubules, interstitial tissue, leydig cells, and tunica albuginea. The results of histomorphometry measurements of bali duck testes showed that the wall thickness of the seminiferous tubules was 23.6760 ± 1.4425 (µm), the number of seminiferous tubules was 421.1000 ± 56.1396 and the thickness of the tunica albuginea was 29.5000 ± 5.048 (µm). Considering the importance of knowledge about the structure of bali duck testicles, it is recommended for future researchers to examine the structure and histomorphometry of bali duck testicles at different ages in the growing phase.
HISTOMORPHOMETRY OF THE DEXTER VENTRICLE OF LOCAL BALI DUCKS AT GROWTH PHASE
Authors: Pasaribu Delima Marsinta Ida , Setiasih Ni Luh Eka , Heryani Luh Gde Sri Surya , Berata I Ketut , Susari Ni Nyoman Werdi , Suatha I Ketut
Published: April 2024

Heart is the main organ in blood circulation which plays a role in pumping blood to all body cells and returning to the heart. Avian heart has four chambers consisting of two atria (dexter and sinister) and two ventricles (dexter and sinister), each chamber has three layers of walls consisting of epicardium, myocardium and endocardium. This study aimed to obtain information about the histological structure and histomorphometry of ventriculus dexter of the bali duck’s heart at grower phase. The study sample used 18 bali ducks, which were divided into two gender groups and each consisted of 9 ducks (3 months old). Ventriculus dexter sample was the processed into a histology preparation by Haematoxylin-Eosin (HE) staining. Anatomy and histology results were analyzed using descriptive qualitative analysis, while histomorphometry used the anova test with mean estimation using the SPSS 26 program. The mean thickness of the epicardium, myocardium, and endocardium in males respectively were 43,11 ± 12,05µm, 1.145,19 ± 133,99µm, 23,41 ± 6,91µm. While in females respectively were 34,98 ± 17,03µm, 1.367,41 ± 412,43µm, 11,86 ± 5,06µm. Histomorphometric data that has been analyzed shows that the results of measuring the thickness of the endocardium are significantly different (P<0,05), while measuring the thickness of the epicardium and myocardium was not significantly different (P>0,05).. It can be concluded that the anatomical structure of the heart and the histological structure of the ventriculus dexter of bali ducks didn’t differ between treatment males and females, but there were differences in the histomorphometry of the endocardial layer. Research on the heart of balinese ducks is still rarely carried out, so further research is needed on the structure and histomorphometry of the epicardium layer, myocardium layer, and endocardium layer of the dexter ventricle or other heart chambers in bali ducks at different phases.
EVALUATION OF PRESERVED ORGANS OF PLASTINATION WITH THE DEHYDRATION PHASE AT ROOM TEMPERATURE
Authors: Susari Ni Nyoman Werdi , Wandia I Nengah , Suatha I Ketut , Heryani Luh Gde Sri Surya
Published: April 2024

Organ preservation is an effort to maintain the integrity of organs for a long time by preventing further damage and decay processes. Plastination is an organ preservation process by inserting polymer materials to maintain the shape and composition of the organ. This research aims to evaluate the product of a plastination technique carried out using generic chemicals in the community and equipment. The organs used in this plastination process are heart, brain and lungs from the bali cattle. The research materials and tools needed are distilled water, formalin, acetone, liquid silicone rubber, silicon catalyst, 10 ml syringe, plastic bag/tub with lid, vacuum chamber, plastic bucket/tub without lid, and hardening room/box. The vacuum chamber is made from a modified drum so that it can accommodate cadaver plastination (large size). The plastination technique is carried out in four main stages, one of which is the dehydration phase with acetone which is carried out at room temperature. The plastinated organs that are the product of this technique will be evaluated for their flexibility, color, and odor. The results of this research produce plastinated organs that have a stiff texture, pale color, and a non-pungent odor. From the research results obtained, it can be suggested that it needs to be stored in a vacuum for longer (for 1 week) so that the texture can resemble its original shape.
HISTOMORPHOMETRY OF EOSINOPHILS AND ERYTHROCYTES OF CONVENTIONALLY REARED BALI CATTLE
Authors: Bahtiar Titi Humairah , Suwiti Ni Ketut , Suatha I Ketut
Published: April 2024

Blood tissue is an indicator of the health status of Balinese cattle. The presence of red blood cells or erythrocytes and white blood cells such as eosinophils is very important because they play a role in the infection process. Therefore, this study aims to determine the histology and morphometry of eosinophils and erythrocytes as well as the number of eosinophils in Balinese cattle raised in a conventional way. The samples used were 30 cows, taken from Balinese cows raised in Bulian Village, Kubutambahan District, Buleleng Regency. The blood tissue was prepared with MDT staining. Morphometric measurement of eosinophil and erythrocyte white blood cells using EP View application with 1000x magnification. Counting the number of eosinophils was done per 100 leukocyte cells. The results showed that eosinophils were round in shape and had a purplish-colored 2-lobed nucleus and bright pink granulated cytoplasm with an average diameter of 5.90 ± 1.04 µm. Erythrocytes have a discocyte shape without a purple nucleus and several variations of elliptocyte shapes with a mean diameter of 3.62 ± 0.19 µm. The mean white blood cell eosinophils of conventionally reared Balinese cattle was 7%. Further research is needed to assess health status by looking at other indicators such as physiological status in conventionally reared Balinese cattle.
CHEMICAL AND PHYSICAL QUALITY OF CHICKEN MEAT (KUB) GIVEN COMMERCIAL RATION IN SUBSTITUTION BREAD WASTE
Authors: N. L. P SRIYANI , SITI N. W. , ARIANA I. N. T. , MIWADA I. N. S.
Published: April 2024

The objective of this study is to assess the chemical and physical quality of meat from Kampung Unggul Balitbangtan (KUB) chickens when they are fed with bread waste. The research utilized a Completely Randomized Design (CRD) comprising 3 treatments and 5 replications, with each replication containing 2 KUB chickens. The three treatments were as follows: (P0) KUB chickens fed a 100% commercial ration, (P1) KUB chickens fed a mixture of 75% commercial ration and 25% bread waste, and (P2) KUB chickens fed a mixture of 50% commercial ration and 50% bread waste. The findings indicated that the substitution of commercial rations with bread waste at levels of 25% and 50% had a significant impact (P<0.5) on the chemical quality of meat, specifically moisture content, protein content, and fat content. In terms of the physical quality of the meat, parameters such as pH, water holding capacity, and cooking losses also showed significant differences (P<0.05). Therefore, based on the research results, it can be concluded that replacing commercial rations with bread waste at the levels of 25% and 50% leads to a decrease in both the chemical and physical quality of KUB chicken meat.
ORGANOLEPTIC VALUE OF BALI BEEF MARINATED WITH TRIGONA HONEY
Authors: D. RAMADHANI , SRIYANI N. L. P. , DEWANTARI M.
Published: April 2024

This’ research aims’ to’ determine’ the’ best effect’ and’ assess the’ organoleptic’ value of’ Bali’ beef after marina- tion using Trigona honey. The meat marination process was’ carried’ out’ for 30’ minutes’ at’ room’ temperature’. The’ research design’ used’ was a’ Completely’ Randomized’ Design’ (CRD) with’ four’ treatments’ and’ seven replica- tions’. The’ four treatments’ included non-marinated meat’ (P0), meat’ marinated’ with’ 5 ml of Trigona honey (P1), meat marinated with 10 ml of Trigona honey (P2), and meat marinated with 15 ml of Trigona honey (P3). The’ vari- ables’ observed’ in’ the study’ included’ color’, aroma’, taste, texture’, tenderness, and’ overall acceptance evaluated by 15 semi-trained panelists. The results showed that marinating Bali beef with Trigona honey significantly influen- ced color, aroma, taste, tenderness, and overall acceptance, but’ did’ not’ have’ a’ significant’ effect’ on’ texture. The’ conclusion’ of this’ study’ is’ that’ the best marination for Bali beef is achieved using Trigona honey at a level of 10 ml, as indicated by the increased values of aroma, taste, texture, tenderness, and overall acceptance by the panelists.
Financial Knowledge, Behavior, and Attitude on The Financial Well-Being of The Sustainable Livelihood Program Associations
Authors: Quibra Rosita Kibra
Published: April 2024

Research Objective: This study evaluates and develop a predictive model on the financial well-being, financial knowledge, behavior, and attitudes of Sustainable Livelihood Program Association (SLPA) officers and members, a program of the Department of Social Welfare and Development (DSWD) under the Pantawid Pamilyang Pilipino Program (4Ps).
 
Theoretical Framework: The study is grounded in the Sustainable Livelihood Program (SLP) Theory of Change, which seeks to understand how institutional initiatives such as policies, strategies, programs, or projects contribute to progressive and sustainable outcomes (Acosta & Avalos, 2018). The financial competencies of Sustainable Livelihood Program Associations (SLPAs), particularly in spending, are strongly influenced by Modigliani and Brumberg's Life Cycle Theory of Consumption and Spending.
 
Methodology: This is a quantitative study using descriptive- correlational design. There are 209 participants consisting of officers and members from selected SLPAs in Malaybalay City.
 
Results: Findings revealed that SLPA officers and members have a moderate level of financial knowledge and attitude. However, financial well-being requires improvement, underscoring a discrepancy between current and desired financial conditions within the association. Moreover, significant relationships exist among financial well-being, financial knowledge, attitude, and behavior.
 
Implications: The communicated findings to DSWD Region X contributes for the enhancement of the implementation of the SLPA. The results on the level of financial well-being will be enhanced when focused is made on the financial knowledge and attitude. The materials for financial education may be revised.
 
Originality or Value: This study contributes to the literature on financial literacy and well-being of the government supported associations to ensure that upliftment on the financial well-being of members.
Wildlife in the Tabuk Region, its Challenges and Protection Mechanisms, from the Islamic and Systemic Perspectives
Authors: Al-Sahli Abdul Rahman Bin Safar Bin Awad
Published: April 2024

Purpose: This research endeavors to safeguard the existence and reproductive capacities of beneficial wildlife organisms against the looming risks of extinction and extermination resulting from detrimental human actions. This endeavor is crucial for upholding environmental equilibrium, sequestering significant volumes of carbon emissions in the atmosphere, and mitigating the perils of swift climate changes. The study seeks to address a meticulously crafted set of inquiries, rooted in scientific and logical interpretation, aimed at devising viable and substantiated solutions. Key queries include rationale behind researching this specific topic, wildlife distribution within the Tabuk region, the efficacy of Islamic law mechanisms in averting and tackling these hazards, and the strategies employed by Saudi national environmental systems in safeguarding animal, plant, and aquatic wildlife.
 
Method: The research methodology involves an exhaustive examination of extant literature in environmental sciences, scrutinizing previous studies that delved into facets or components akin to the present research's domain. This approach contributes to augmenting the information reservoir concerning wildlife, its constituents, and functionalities. Furthermore, it addresses gaps discerned in prior research endeavors, thereby enhancing comprehension of the subject matter and obliterating ambiguities.
 
Implications of the research: By shedding light on the paramount issues and challenges imperiling wildlife organisms with extinction, the study underscores the imperative of implementing mechanisms outlined in Islamic law and Saudi national environmental systems. It strives to catalyze proactive measures for wildlife conservation, thereby fortifying ecological resilience and sustainability.
 
Originality/value: This research delineates a comprehensive analysis of wildlife conservation challenges and solutions, particularly within the purview of Islamic law and Saudi national environmental frameworks. It offers novel insights into mitigating threats posed to wildlife, augmenting existing knowledge, and furnishing recommendations to bolster conservation efforts.
Gender Security in EU Member-States and Ukraine
Authors: Tokar Volodymyr
Published: April 2024

Purpose: This article explores gender security within the economic frameworks of EU member-states and Ukraine. It aims to expand the definition of gender security beyond traditional concepts of conflict resolution and violence prevention, focusing on economic stability and equality. The article analyzes the impact of economic policies, labor market dynamics, healthcare systems, and social policies on gender security, contributing to a broader understanding of the concept.
 
Methods: The study employs a quantitative methodology using a robust set of indicators across demographic, macroeconomic, and social security parameters. These indicators include predefined threshold values for evaluating economic and gender security. Countries are assigned numerical rankings based on their performance against these thresholds, with a focus on female-to-male ratios in key areas.
 
Results and conlcusions: The research reveals significant disparities in gender security across EU member-states and Ukraine. Spain and Sweden demonstrate superior healthcare and socio-economic conditions, reflected in high female life expectancies and low infant mortality rates. In contrast, Bulgaria, Romania, and Ukraine exhibit lower life expectancies and higher infant mortality rates, highlighting challenges in healthcare and economic stability. The study also finds discrepancies in unemployment rates between genders, indicating varied economic conditions and societal norms.
 
Implications: The findings can inform targeted policy interventions in healthcare, employment, and social welfare to address gender-specific challenges. By understanding disparities in gender security, policymakers can design more effective strategies to promote gender equality and economic stability. The article’s comprehensive approach provides a nuanced view of gender security, crucial for shaping policies that address both female and male economic securities.
 
Originality / value: This article contributes to gender security research by providing a comprehensive, gender-centric analysis of economic security in the EU and Ukraine. It stands out from previous studies by integrating a wide range of economic indicators to understand the interplay between economic conditions and gender equality.
Unlocking Business Success: The Role of Financial Literacy, Innovation Capability, and Government Support
Authors: Ahdanisa Syakina , Tarmidi Deden
Published: April 2024

Purpose: This study aims to analyse the effect of financial literacy and innovation capability on business performance with government support as a mediating variable.
 
Theoretical framework: Government Support as a mediation was analyzed the effect of financial literacy and innovation capability on business performance.
 
Method: A quantitative methods approach was used by distributing questionnaires to 110 Food & Beverage MSME in Jakarta Area. The data collection process was carried out using google form, then analysed using path analysis processed using Smart-PLS.
 
Result: This study found that financial literacy has positive impact on government support but innovation capability has not, then innovation capability and government support have the positive effect on MSME performance, but financial literacy has no impact on MSME performance. The mediation test found that government support mediates the effect of innovation capability and financial literacy on MSME performance.
 
Research, Practical & Social implications: This finding suggests that the government as a regulator should continue to increase its support for MSME actors so as to improve the performance of MSME businesses. This finding encourages MSME actors to have strong instincts in creating and implementing the latest innovations in their business to get government support in improving their business.
 
Originality/value: This study uses 3 business performance indicators using primary data which are usually used in analysing the company's secondary data, with sufficient validity and reliability results, the use of these indicators is also suitable in analysing business performance in primary data.
The Influence of Transformative Learning, Affective Commitment, Digital Transformation, Capability Dynamic, Ambidexterity, and Education Policy Toward Educational Leadership: A Case from Indonesia
Authors: Primahendra Riza , Purba John Tampil , Ugut Gracia Shinta S , Budiono Sidik
Published: April 2024

Purpose: The implications of external environment changes and the presence of a new generation of students in the school to the school leadership are often overlooked. Very few studies elaborate on the need to shape educational leadership concepts and practices to deal with the changes. The study intention is to identify the influences of transformative learning, affective commitment, digital transformation, capability dynamic, and the ambidexterity to educational leadership, and to craft the educational leadership based on Indonesia context.  
 
Design/Methodology/Approach: The study is using Covariance Based Structural Equation Modelling (CB-SEM), the data is collected through a Likert based questionnaire from 271 respondents and it is processed by SPSS and AMOS.
 
Findings: Transformative Ethics Agile (TEA) Leadership as educational leadership is influenced by Ambidexterity, transformative learning, affective commitment, and educational policy. Digital transformation and capability dynamic have insignificant influences, however ambidexterity mediating the influence of dynamic capability to TEA Leadership.
 
Research Implications: The research contributes to renewing educational leadership concepts by putting emphasis on transformative, ethics, and agile elements. The variables that must be put into attention for leading school during changing time, specifically ambidexterity, transformative learning, affective commitment, and educational policy. The research highlights the importance of context on educational leadership.
 
Originality/Values: The research contributes to the identification of variables that influence the effectiveness of school leadership and by doing that able to facilitate the strategy of leadership development for school management. The values of the research are on the mapping of factors contribute to educational leadership and lead the practical aspects of managing school in the changing time.
Tolerance to paradoxical increase in motor activity caused by inhibition of phosphodiesterase 10a in a model of hypodopaminergy
Authors: Dorotenko A. R. , Sukhanov I. M. , Savchenko A. A. , Dravolina O. A. , Belozertseva I. V.
Published: April 2024

Introduction. Phosphodiesterases (PDEs) are a group of enzymes that hydrolyze the phosphodiester bond in cyclic nucleotides. PDE10A is mainly present in the medium-sized spiny neurons of the striatum. Functionally, PDE10A inhibition imitates the effect of D1-like agonists and D2-like dopamine receptor antagonists, and simultaneously modulating “direct” and “indirect” striato-thalamo-cortical brain pathway. To date, the effects of PDE10A inhibition have been characterized mainly, reproducing the inhibitory motor activity of D2-like dopamine receptor antagonists.

The objective was to evaluate the stimulating motor activity of the effect of PDE10A inhibitors, as well as the possible development of tolerance to these effects when they are re-administered.

Methods and materials. The hypodopaminergic state in male Wistar stock rats was modeled by administration of the VMAT2 inhibitor tetrabenazine (3 mg/kg). The effects of selective inhibitors PDE10A, MP-10 (0.3–5 mg/kg) and RO5545965 (0.1–0.9 mg/kg), on the motor activity of rats were evaluated with single and repeated administration (5 and 10 days).

Results. Switching off PDE10A dose-dependently stimulated the motor activity of rats after administration of tetrabenazine. However, repeated administration of PDE10A inhibitors was accompanied by the development of tolerance to their paradoxical stimulating effect.

Conclusion. The development of tolerance may limit the potential clinical use of PDE10A inhibitors to correct hypodopaminergic symptoms in patients with Parkinson’s disease. It is necessary to study the molecular mechanism of this phenomenon.
Association of the p.I148m polymorphism in the PNPLA3 gene with the severity of nonalcoholic fatty liver disease in various clinical groups
Authors: Sidorenko D. V. , Nazarov V. D. , Lapin S. V. , Emanuel V. L. , Raikhelson K. L. , Gomonova V. P.
Published: April 2024

Introduction. Non-alcoholic fatty liver disease in most cases is closely associated with diseases such as obesity and type 2 diabetes mellitus, however, this dependence is not observed in a number of patients. In this case, hereditary factors, such as the p.I148M polymorphism of the PNPLA3 gene, play the greatest role in the prognosis of the course of the disease.

The objective of the study was to evaluate the effect of the p.I148M polymorphism of the PNPLA3 gene on the course of NAFLD in subgroups of patients with and without concomitant metabolic pathology.

Methods and materials. The study group included 212 patients with NAFLD who underwent p.I148M genotyping of the PNPLA3 gene. The severity of the disease was assessed in the general group (group P) and in subgroups of patients with the absence and presence of obesity (subgroups O– and O+, respectively) and type 2 diabetes mellitus (subgroups D– and D+). The severity of the disease was assessed by the severity of cytolytic syndrome (ALT level), hepatic steatosis and fibrosis (the value of CAP and liver stiffness according to transient elastometry) within clinical subgroups between carriers of different PNPLA3 genotypes.

Results. Higher ALT levels were found in homozygous carriers of p.I148M compared with the reference genotype (CC/GG) in the subgroups P, D–, D+ and O– (p=0.012; p=0.012; p=0.028 and 0.042, respectively), as well as when comparing the general group of carriers with reference genotype (CC/CG+GG) in subgroups P and D– (p=0.036 and p=0.015). More severe steatosis was found in homozygous carriers compared to the reference genotype (CC/GG) in group P (p=0.017) and subgroup O– (p=0.019). Higher values of liver stiffness were noted in the modified PNPLA3 genotype when comparing the reference (CC/CG) genotype with heterozygotes in group P (p=0.027) and subgroup D– (p=0.006) and when comparing the reference genotype with the general carrier group (CC/CG+GG) in subgroup D– (p=0.009).

Conclusions. The carriage of p.I148M of the PNPLA3 gene in patients without metabolic disorders (obesity, type 2 diabetes mellitus) is associated with the formation of cytolytic syndrome, steatosis and liver fibrosis.
Early form of mitochondrial epileptic encephalopathy due to primary deficiency of coenzyme Q10
Authors: Melashenko T. V. , Laptiev S. A. , Malekov D. I. , Fomina M. Yu. , Novoselova O. G. , Bikanov R. A. , Tsibulskaya D. S. , Smirnova A. V.
Published: April 2024

Epileptic encephalopathy (EE) is a group of genetic monogenic diseases with leading feature of intractable epilepsy with onset at an early age and the development of neurocognitive deficit. Thanks to the development of molecular genetic diagnostic methods, more than 90 hereditary forms of EE have been identified, more of which have been discovered over the past decade. EE can be associated with impaired molecular function of neuron transporters (voltage-dependent and ligand-dependent transporters), metabolic disorders, and chromosomal diseases. Among monogenic EE, a group of diseases is distinguished, in which brain damage and the development of epilepsy are caused by hereditary disorders of mitochondrial functions. Given the wide variety of forms of mitochondrial dysfunctions, the absence of specific manifestations, different age of manifestation, the diagnosis of this group of diseases is not a routine process and requires DNA test (whole-exome/genome sequencing, gene panels). With the creation of new drugs that correct mitochondrial disorders, in-time diagnosis of mitochondrial dysfunctions, identification of a genetic disorder contributes to the in-time manage of pathogenetic treatment, the choice of an antiepileptic drug, which can reduce the risk of mortality and the degree of patient disability. We describe the case of early neonatal epilepsy in the structure of hereditary deficiency of coenzyme Q10. However, unfortunately, the late started specifical energotropic therapy and the severe course of the disease led to an early death. Hereditary defects in coenzyme Q are rare genetic disorders. In this regard, for the specialists leading the patient, the discovery of this particular defect was most likely an “unexpected” finding. Considering the complexity and duration of the whole exome study, the severity of the phenotype and the delay in energotropic therapy, the course of the disease in the child turned out to be extremely unfavorable. The presentation of the clinical case, in our opinion, will be important for practitioners who rarely encounter this type of pathology.
A Russian regional draft commission report on quality control efforts regarding medical examination of conscripts
Authors: Kuzmin S. A. , Grigorieva L. K.
Published: April 2024

Introduction. In Russian constituents, draft commissions play the leading role in providing medical services to individuals preparing for military service.

The objective of the study is to analyze activities of a regional draft commission located in the Orenburg region with a specific focus on quality control during medical examination of conscripts.

Methods. The study relied on reports and records of the Military Medical Expertise Center at the Federal Budgetary Institution “Military Commissariat of the Orenburg Region” throughout 2012 to 2021 timespan.

Results and analysis. Within the analyzed 10 year’s timespan the number of conscripts in the Orenburg region decreased by 11.6 %. However, the number of individuals fit for military service (categories “A”+”B”) remained relatively unchanged, e.g. 14058 individuals in 2012 and 14837 in 2021 (except years 2013 and 2014 with 12494 and 12880 individuals in this category, respectively). The ratio between the individuals potentially fit for military service to those actually deployed indicates the rate of conscription withdrawal rate. In 2020 the conscription withdrawal rate was at its minimum value of 26.7 %, reaching its maximum value of 38.8 % in 2013. Within the timespan under study, 47500 individuals residing in the region were conscribed for combat deployment. Following medical examination, 1793 (3.8 %) applicants were withdrawn from conscription as unfit for military service. Within the first three months of military service, 29 (0.06 %) military personnel were dismissed from service for health reasons and general disease diagnosis. Some 52.200 individuals were deferred or exempted from the military draft (fitness categories for military service “B”, “G”, “D”), of which 28200 (54.1 %) were called for a medical revision examination. 2536 citizens were recognized as appropriate for military service (suitability categories “A” + “B”), amounting to 10.1 % of the arrived conscripts.

Conclusion. Timely medical examinations of individuals upon conscription for military service, as well as medical and recreational activities for conscripts depend on the due and well-coordinated operation of regional conscription commissions. Under the resolution of the President of Russia on efforts to increase the corps of the Armed Forces of the Russian Federation, more extensive resources of potential military culture scripts are required.