bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemical Tagging of N-Alkylamine-Containing Natural Products and Pharmaceuticals through C(sp3)–H Functionalization
Authors: Zhao Cunyuan , Wang Yuankai , Steele Andrew , Mori Soichiro , Shen Ben , Wasa Masayuki
Published: August 2024

Development of efficient protocols for introducing handles into natural products and pharmaceutical agents that are suitable for bioconjugation is a compelling research objective. One attractive option would involve chemical tagging through late-stage C–H functionalization, but such strategies are uncommon. The primary challenge lies in the lack of catalyst systems that can chemo- and site-selectively cleave relatively inert C–H bonds. In this study, we demonstrate that bioactive N-alkylamine-based natural products and other small-molecule drugs can be modified in order to facilitate bioconjugation. Moreover, we show that under blue light irradiation, flavin analogues can promote oxidation of bioactive amines by sequential scission of α- and β-amino C–H bonds. Engagement of the resulting enamines in an inverse electron-demand Diels-Alder process with tetrazines can be used to achieve an array of structural modifications. Notably, the transformation occurs under mild, pH-neutral, and aerobic conditions. The utility of the approach is highlighted by a facile synthesis of antibody–drug conjugates involving anti-cancer agent irinotecan.
Smoother Semiclassical Dispersion for Density Functional Theory via D3S: Understanding and Addressing Unphysical Minima in the D3 Dispersion Correction Model
Authors: Tkachenko Nikolay , Head-Gordon Martin
Published: August 2024

One of the most widely used and computationally efficient models that accounts for London dispersion interactions within density functional theory (DFT) is the D3 dispersion correction model. In this work, we demonstrate that this model can induce the appearance of unphysical minima on the potential energy surface (PES) when the coordination number of atoms changes. Optimizing to these artifactual structures can lead to significant errors in determining the interaction energy between two molecules and in estimating the thermodynamic properties of the system. In several specific examples, such as Kuratowski-type H2-NiKur and H2-PdKur clusters, these local minima exhibited extremely high PES curvature, resulting in incorrect estimations of harmonic frequencies and significant overestimations of zero-point energy and enthalpy values. Although such erroneous behavior of the D3 model is relatively rare, it can occur across a wide range of chemical species, including molecules like the [Li(C6H6)]+ complex and the dispiro(acridan)-substituted pyracene (DSAP) molecule. Our analysis reveals that the root of the problem lies in the definition of the AB atomic-pair dependent C6AB coefficients in the D3 model. To address this issue, we propose a re-parameterization of the D3 model by introducing a modified C6AB functional form that now depends on the specific pair of considered atoms. This new model, termed D3-Smooth (or D3S for short), is designed to smooth out the PES associated with the dispersion correction. By doing so, we demonstrate that D3S eliminates unphysical local minima while maintaining the quite satisfactory accuracy of the parent D3 method in interaction energy benchmark sets. For example, the RMS difference between using the D3(BJ) correction to B3LYP and the D3S(BJ) correction across the large MGCDB84 dataset of nearly 5000 data points is only 0.12 kJ/mol. Similar results are obtained for every other D3-corrected functional tested. Consistent with this result, no significant improvement could be obtained for the B3LYP-D3S(0) correction by reoptimizing the damping function.
Systematic, computational discovery of multicomponent reactions and one-pot sequences.
Authors: Roszak Rafał , Gadina Louis , Wołos Agnieszka , Makkawi Ahmad , Mikulak-Klucznik Barbara , Bilgi Yasemin , Molga Karol , Gołębiowska Patrycja , Popik Oskar , Klucznik Tomasz , Szymkuć Sara , Moskal Martyna , Baś Sebastian , Mlynarski Jacek , Grzybowski Bartosz A.
Published: August 2024

Discovery of new types of reactions is essential to organic chemistry because it expands the scope of molecular scaffolds that can be made and can help trace new and more economical syntheses of existing structures1-4. Within the spectrum of all possible reaction classes, those that build complex scaffolds from multiple simple components in one step (i.e., multicomponent reactions, MCRs5-11; Figure 1a) and/or proceed sequentially in one pot12-14 are appealing as they may capitalize on the use of unstable intermediates, minimize separation and purification operations, and increase the overall step- and atom-economy15 as well as “greenness”16,17 of synthesis. However, the number of known MCR classes remains limited to several hundred (Figure 1b and interactive map at https://mcrmap.allchemy.net), and the number of publications reporting new ones appears to decrease in recent years (Figure 1c), perhaps because the most popular reactivity patterns (e.g., isocyanide, β-dicarbonyl, or imine-based MCRs) and their straightforward extensions and combinations18 have been studied in nearly exhaustive detail. The discovery process continues to rely, per Ivar Ugi’s famous quote, on thoughtful “reflection […] or combinatorial techniques,”5 and even when supported by high-end quantum mechanical methods, requires prior knowledge of “fitting” substrates (e.g., recent ref. 19 vs. closely analogous MCRs from earlier ref. 20,21). The “reflection” regards not only the choice of substrates but, above all, careful consideration of possible cross-reactivities between numerous intermediates, reagents, and side-/by-products present in a multicomponent mixture – in effect, translating into a laborious analysis of complex networks of mechanistic steps. Here, we show that computers equipped with accurate and broad knowledge of mechanistic transforms can perform such network analyses rapidly and in a high-throughput manner, and can guide systematic discovery, ranking, and yield estimation of unprecedented types of MCRs, one-pot sequences and even organocatalytic reactions, several of which we validate by experiment. These results evidence that synthesis-planning algorithms are no longer limited to skillful manipulation of the existing knowledge-base of “full reactions”22-28 but can assist in its creative expansion.
THE ROLE OF BRAND IMAGE AS A MEDIATION OF THE INFLUENCE OF PRODUCT PRICE AND QUALITY ON PURCHASE DECISION
Authors: Yaqin Mohammad Nurul , Askafi Eka , Arisyahidin Arisyahidin
Published: August 2024

This research aims to determine whether the product's Price and quality influence the brand image and purchasing decisions of collapsed beef among residents in Jombang Regency. This study uses a quantitative approach. The population in this study was Jombang residents, while the sample used was 100 people, determined using the Slovin formula. This research uses primary data obtained through distributing questionnaires. The analytical tool used is influenced by the Price and quality of the product, which influences the brand image of collapsed beef, to find out how Price, product quality, and brand image influence the decision to purchase collapsed beef and to find out whether the brand image can mediate the influence of price and product quality on beef purchasing decisions collapse. The method used in this research is a survey method, where the author distributes questionnaires for data collection. The approach used in this research is quantitative. Data analysis using smartPLS SEM software. The research results show that Price has a positive contribution to brand image, while product quality does not contribute to brand image. Apart from that, Price also contributes positively to purchasing decisions. However, product quality does not contribute to purchasing decisions. The brand image also influences purchasing decisions. Brand image can partially mediate price influence on purchasing decisions but cannot influence product quality.
RISK ANALYSIS FOR THE DEVELOPMENT OF XYZ RESIDENCE
Authors: Dewie Saktia Ardiantono , Satrio Hestu Pidekso
Published: August 2024

Population growth in Indonesia creates new challenges for the housing sector. Scarcity in Jakarta and high land prices make residents actively look for alternative housing options in neighboring areas such as Bogor. This causes increased competition between housing development companies, including the XYZ residence project. This research uses the severity index to analyze, evaluate, prioritize and suggest strategies for managing construction-related hazards in the xyz housing area project. From the research results it appears that in the temporal dimension of the XYZ residence construction project, 28 hazards have a very low probability of affecting the project schedule, 14 hazards have a low probability, 2 (two) hazards have a medium probability, 3 (three) hazards have a high probability, and 4 (four) danger has a very high probability. Likewise, the evaluation of the level of risk in the cost aspect of the xyz residence development project shows that 36 risks have a very low probability of influencing project costs, compared to 5 (five) low risks, five medium risks, 1 (one) high risk, and 4 (four) very high risks. For this reason, it is necessary to implement measures that impact the financial dimension.
Analysis of Digital Trade Virtual Simulation Comprehensive Training System
Authors: Zhang Xiao
Published: August 2024

In the era of digital trade, business activities are borderless and cutting-edge technology and digital trade are deeply integrated, posing new challenges to talent. Therefore, building a digital trade virtual simulation comprehensive training system and cultivating students’ practical skills and innovative abilities through immersive experiences is the key to cultivating high-quality and versatile international trade talents. This article delves into the difficulties and importance of constructing a comprehensive digital trade training system and designs a virtual simulation system framework around key areas such as international trade, cross-border e-commerce, digital marketing and business data analysis, in order to provide practical paths and strategic thinking for talent cultivation.
Research on the Training Model of Internationalized Applied Talents in New Engineering
Authors: Wang Qun
Published: August 2024

One of the core elements of the New Engineering reform is exploring a new talent cultivation model. Based on this, the author will start from the three elements of talent cultivation mode: talent cultivation goals, talent cultivation process and talent cultivation quality evaluation. From the perspective of New Engineering disciplines, this paper provides a detailed analysis of the construction process of the current training model for international applied talents in universities, explores the path of engineering education reform and hopes to provide more international New Engineering applied talents for the development of China.
Value Logic of Talent Cultivation Quality in Evaluation Model for Vocational Colleges in New Era
Authors: Meng Ran , Li Yujie
Published: August 2024

The value orientation of vocational colleges’ current talent cultivation quality evaluation model has become alienated regarding goals, functions, means and methods. Vocational colleges should reconstruct value guidance, enhance goal identification and emotional resonance, abandon utilitarianism and balance value rationality and instrumental rationality, highlight the application of technology, balance knowledge and skills with professional qualities, strengthen process evaluation, and effectively combine result evaluation with process evaluation. In addition, it is important to build a “Four in one” talent training quality evaluation model for vocational colleges, including goals, functions, means and methods, and continuously improve the quality of vocational education professional talent training.
ВЛИЯНИЕ РЕГУЛЯТОРНОЙ СРЕДЫ НА ДИНАМИКУ РАЗВИТИЯ СЕКТОРА МАЛОГО ПРЕДПРИНИМАТЕЛЬСТВА В ДОНЕЦКОЙ НАРОДНОЙ РЕСПУБЛИКЕ: АНАЛИЗ И ПЕРСПЕКТИВЫ
Authors: ПЕТРУШЕВСКАЯ ВИКТОРИЯ ВИКТОРОВНА , ШАРЫЙ АНДРЕЙ НИКОЛАЕВИЧ
Published: August 2024

В статье рассмотрено определение малого предпринимательства, выявлены ключевые направления и механизмы регуляторной политики развития сектора малого предпринимательства в Донецкой Народной Республике. Определено место Российской Федерации в рейтинге стран «Doing Business» по уровню регуляторного климата относительно стимулирования деловой активности. Также в данном исследовании предложены направления оптимизации региональной регуляторной политики в области развития малого предпринимательства в Донецкой Народной Республике.
Development and Characterization of a Zeolite Based Drug Delivery System: Application on Cannabidiol Oral Delivery
Authors:   ,   Lebanese American University -- Chouran Beirut, Dernaika Fouad
Published: August 2024

The growing interest in the therapeutic potential of cannabidiol (CBD) has led to the need for effective and reliable delivery methods that overcome its low oral absorption. Zeolites, a class of porous nanoparticles, offer unique advantages as drug carriers due to their high surface area and adjustable pore size. In this study, a zeolite-based drug delivery system was developed for the encapsulation of CBD. The zeolite particles were characterized before and after loading using various techniques including Scanning Electron Microscopy (SEM), Brunauer-Emmett-Teller (BET) and Thermogravimetric analyzer (TGA). The drug encapsulation efficiency, and the release profile of CBD from the zeolite matrix were evaluated in addition to in vitro dissolution experiments in the intestinal and gastric simulated fluids. The results showed that the loaded zeolite particles exhibited high encapsulation efficiency of 73.5 %. When compared to CBD containing particles in a commercialized capsule, the in-vitro dissolution rate of CBD loaded zeolite was significantly higher after 30 minutes in the simulated stomach (pH 1.8) and the intestinal (pH 6.8) fluids, 67.8 % versus 43.6% and 62.6 % vs 38.4 % respectively. Our findings open new avenues for the use of zeolites as an efficient drug delivery system for drugs with low bioavailability similar to CBD.
Semiótica de las emociones: la centralidad del consumo en la formación de imaginarios y como fuente de emociones
Authors: Perez Clotilde
Published: August 2024

El texto presenta resultado de la investigación teórica sobre las emociones humanas, na articulación entre la semiótica de Peirce, la antropología de los sentidos y la psicoanalásis, compreendendo la centralidad del consumo en la formación de imaginarios y, por supuesto, como fuente de emociones. Propone una discusión sobre las conexiones entre sensaciones, sentimientos y emociones, en una mirada múltiple. Las reflexiones siguen a partir de la comprensión del consumo como ritual de construcción y circulación de significados, mucho más amplios que las meras transaciones comerciales. Busca una mirada que dialoga con la tradición europea y los aportes teóricos latinoamericanos, con vistas a pertinencia de las contribuciones a las epistemologías del sur global. Las conclusiones siguen por la comprensión del consumo como expresión de identidad, autoconocimiento, ciudadanía, bien-estar y amor, sin dejar de lado las críticas a sus límites. Así, mas allá de la formación de imaginarios, la ecología publicitaria, lenguaje del consumo, tornase fuente privilegiada de las emociones contemporáneas.
PELATIHAN PENINGKATAN KESADARAN HALAL DI KALANGAN PENGURUS KOPONTREN AL-AMIEN PRENDUAN SUMENEP MADURA
Authors: Al Fadholi In Amir Ridho , Humairoh Sitti
Published: August 2024

Not many people are aware of the importance of halal products. When people use a product, people often pay little attention to halalness. People's behavior when buying products is sometimes only based on orientation towards the products they like. In line with the implementation of the Halal Product Guarantee Law (RUU-JPH) Number 33, 2014, one of the articles of which states that all products must be certified halal, halal awareness of food products and other products will be raised regarding the presence or absence of non-halal components. halal is absolutely necessary. Therefore, it is very necessary to carry out outreach and training regarding halal awareness through community service programs. Community service activities followed by the KKNT program within the al-Amien Prenduan Islamic Boarding School Cooperative, Sumenep Madura have been carried out well. Even though various obstacles are still found in its implementation, this is a norm in human life. The level of success of this service activity can be seen from the enthusiasm of the Kopontren managers in participating in this activity. Furthermore, it is hoped that halal awareness and literacy levels will increase among Kopontren managers and the surrounding community who provide various food needs for students and boarding school residents, so that all food and beverage products are guaranteed to be halal by submitting them to obtain a halal certificate.
Website-Based Wudu Interactive Learning Animation to Increase Students' Learning Enthusiasm
Authors: Setiawan Fariz Hendra , Azano Mario , Febriansyah Andre Rivaldo , Muvid Muhamad Basyrul
Published: August 2024

Website-Based Wudu Learning Animation is an innovation in wudu learning aimed at the younger generation, especially young children. In this lesson, animation is used to clarify the ablution process and make it interesting for children so as to improve the quality of their worship. The method used is the development of a website that contains interactive animations that show the steps for ablution visually. Each step is equipped with an explanation that is easy to understand and that children can follow. The result of this development is a learning website with the name (Wudu Splash) which can be accessed by anyone and at any time online and for free. It is hoped that with this website (Wudu Splash), users can more easily understand and master the correct ablution techniques, as well as improve the quality of their worship.
Towards a heart-centred philosophy: Embracing poetry as transformative practice
Authors: Abraham Danna
Published: August 2024

Traditional educational practices often impose constraints on the connection between learners and their educational opportunities. A heart-centred philosophy serves as a response to the prevalent pedagogical methods entrenched in academic educational systems. The focus of this work is the transformative potential of poetry in fostering the conditions for the realisation of a heart-centred education. Poetry serves as a catalyst for establishing new forms of interaction with learners, while a heart-centred pedagogy stimulates a profound sense of liberation and connection that can flourish within the classroom. By encouraging learners to reflect on their personal narratives, ethical choices, and aspirations, the focus of concentration is to cultivate a space where critical thinking and emotional engagement while challenging traditional educational norms and empowering learners to embrace connection.
VISUAL REPRESENTATION OF DALITS IN THE CARTOONS OF KERALAM: THE QUESTION OF APTNESS AND ADEQUACY
Authors: Dr. Basil Thomas  , Dr. Gem Cherian
Published: August 2024

Power and hierarchy have always been intertwined with the social transactions in every culture, and this is true not only in the larger social institutions like religion and education, but even in the smaller social units like family and neighborhood as well. One’s position in the hierarchy has been the criterion for exploitation and discrimination in the society, and this has been especially true in the case of Dalits in India. Even in aesthetic forms of expression including art, discrimination based on caste is evident. Dalits in Indian art forms have either been under-represented, mis-represented or not represented at all. The genre of cartooning is no exception in this scenario either. Dalits have been victims of marginalization, discrimination and social exclusion with respect to their social living, but the situation of Dalits is not any different in the earlier representations in literature as well. The cartoons of Keralam incorporated the social structure of the state during its formative years to modernity. The absence of Dalit representation in the cartoon columns demand a scrutiny. As Dalits are not presented in the cartoons dealing with issues like education, employment and Gulf migration, it has to be assumed that they were denied of the opportunity to these imperatives, therefore missing from the social forefront, unable to be represented in cartoons. The paper assumes that there is an underlying social, communal and economic power struggle beneath the naïve periphery of the narrative framework of cartoons in Malayalam, both in the creative and the productive arenas. This paper is an attempt to find out the adequacy and aptness of representation of Dalits in the cartoons of Toms, with the objective to see whether such an absence and misrepresentation is accidental or deliberate. Toms’ cartoons are crucial in the cartooning history of Keralam because they have engaged as a mirror of the society of the state for these fifty years and as a major cartographer of the state, the societal divisions in his cartoons deserve to be studied and hence the Dalit representation in them requires special attention. This paper analyses the cartoons of Toms to find whether the representation of Dalits is apt or adequate.
ALIGNING STRATEGIC HR MANAGEMENT WITH BUSINESS OBJECTIVES: EXAMINING THE EFFECT ON ORGANIZATIONAL EFFECTIVENESS AND PERFORMANCE
Authors: Arora Sonam , Malhotra Latika , Ruhil Madhu
Published: August 2024

In today's dynamic business environment, aligning strategic Human Resource (HR) management with organizational objectives is crucial for enhancing effectiveness and performance. This paper explores the impact of strategic HR management on organizational effectiveness and performance by examining how aligning HR practices with business goals contributes to overall success. It delves into the theoretical foundations of strategic HR management, emphasizing the role of HR in shaping organizational culture, driving performance, and achieving strategic objectives. The study uses a combination of literature review and case studies from various industries to highlight best practices and illustrate how strategic HR alignment leads to competitive advantage. Key findings reveal that organizations that successfully integrate HR strategies with business goals experience improved employee engagement, higher productivity, and better organizational outcomes. The paper concludes with practical recommendations for HR professionals and business leaders on how to effectively align HR strategies with organizational objectives to drive sustainable growth and performance.
“Dança Brasil”: olhares sobre as danças regionais na escola
Authors: Neves Carlos Eduardo , Mizuno Lemos Fábio Ricardo
Published: August 2024

“Dança Brasil”: olhares sobre as danças regionais na escola
ResumoO objetivo da pesquisa foi desenvolver e analisar uma sequência didática de 18 aulas sobre danças regionais brasileiras, inseridas em uma disciplina eletiva para os anos finais do ensino fundamental. Para isso, foi utilizada uma Intervenção Pedagógica que envolveu 37 alunos(as) matriculados(as) na disciplina eletiva “Dança Brasil”, em uma escola da Rede Estadual do interior do Estado de São Paulo. A coleta de dados incluiu registros dos diálogos estabelecidos e a descrição de toda sequência didática, ocorrida no primeiro semestre de 2023, em diário de bordo. Para análise dos dados, foi utilizado o desenvolvimento de categorias de codificação, culminando nas seguintes categorias: A) Fatores Organizacionais e Pedagógicos da Prática Docente; B) Motivações para a Escolha e Ludicidade; C) Protagonismo dos(as) Participantes.Palavras-chave: Educação Física Escolar. Danças Regionais Brasileiras. Diversidade Cultural.
“Dance Brazil”: perspectives on regional dances in school
AbstractThe objective of the research was to develop and analyze a didactic sequence of 18 classes on Brazilian regional dances, integrated into an elective course for the upper years of elementary school. A Pedagogical Intervention involved 37 students enrolled in the elective course "Brazil Dance" at a State School in the interior of São Paulo State. Data collection included records of dialogues and a description of the entire didactic sequence, occurring in the first semester of 2023, documented in a logbook. For data analysis, the development of coding categories was used, resulting in the following categories: A) Organizational and Pedagogical Factors of Teaching Practice; B) Motivations for Choice and Playfulness; C) Protagonism of Participants.Keywords: School Physical Education. Brazilian Regional Dances. Cultural Diversity.
“Danza Brasil”: miradas sobre las danzas regionales en la escuela
ResumenEl objetivo de la investigación fue desarrollar y analizar una secuencia didáctica de 18 clases sobre danzas regionales brasileñas, integradas en un curso electivo para los últimos años de la educación primaria. Una Intervención Pedagógica involucró a 37 estudiantes inscritos en el curso electivo "Danza Brasil" en una escuela estatal en el interior del Estado de São Paulo. La recolección de datos incluyó registros de diálogos y una descripción de toda la secuencia didáctica, que tuvo lugar en el primer semestre de 2023, documentada en un diario de a bordo. Para el análisis de datos, se utilizó el desarrollo de categorías de codificación, culminando en las siguientes categorías: A) Factores Organizacionales y Pedagógicos en la Práctica Docente; B) Motivaciones para la Elección y Ludicidad; C) Protagonismo de los Participantes.Palabras clave: Educación Física Escolar. Danzas Regionales Brasileñas. Diversidad Cultural.
Mandibular analysis of Beta thalassemia patients from hematological institutes of Karachi Pakistan.
Authors: Syed Muhammad Ali  , Syed Mahmood Haider  , Kashif Ikram  , Muhammad Uzair  , Sana Ahmed  , Syed Azhar Matloob
Published: August 2024

Objective: To study the mandibular changes in the β-thalassemia major patient. Study Design: Cross sectional study. Setting: Husaini Blood Bank and Institute of Hematological Diseases Karachi, Department of Oral and Maxillofacial Surgery, and Department of Orthodontics, Baqai Dental College Baqai Medical University, Karachi. Period: January 2023-December 2023. Methods: 50 Orthopanthogram (OPG) radiographs of beta-thalassemia major patient were taken, analyzed and compared to check any variation from normal. Fifty diagnosed β-thalassemia major patients were voluntarily selected through convenience sampling. The study was carried out in collaboration of Husaini Institute of Blood Diseases Karachi, National institute of Oral Diseases Karachi Pakistan and, Department of Oral and Maxillofacial Surgery and department of orthodontics Baqai Dental College Baqai Medical University. Results: 18 (36%) patient’s alteration of trabecular pattern are present and in 32 (64%) patient alteration of trabecular pattern absent. Similarly, in 16 (32%) patients have short spiky roots are present and 34 (68%) patients short spiky roots absent. Conclusion: Effect of anemia is not so profound in mandible of thalassemia patients from population of Karachi.
Saúde Integral: Perspectivas Multidisciplinares, Desafios e Estratégias para o Século XXI
Authors: Silva Antônio Veimar da , Silva Carla Michelle da , Romão Adriano Alves , Silva Thuanny Mikaella Conceição
Published: August 2024

O livro "Saúde Integral: Perspectivas Multidisciplinares Desafios e Estratégias para o Século XXI" é uma obra que reúne o conhecimento e a expertise de diversos profissionais dedicados à saúde e ao bem-estar. Organizado por Antônio Veimar da Silva, Carla Michelle da Silva, Adriano Alves Romão e Thuanny Mikaella Conceição Silva, esta coletânea aborda os desafios e as estratégias necessárias para promover uma saúde integral no século XXI.
O livro "Saúde Integral: Perspectivas Multidisciplinares Desafios e Estratégias para o Século XXI" oferece uma visão abrangente e multidisciplinar dos diversos aspectos da saúde integral. Ao abordar temas que vão desde a saúde mental até a nutrição e as políticas de saúde, a obra proporciona uma compreensão profunda e prática dos desafios e das estratégias necessárias para promover a saúde no século XXI. Esta coletânea é uma leitura essencial para profissionais da saúde, pesquisadores, acadêmicos e todos aqueles comprometidos com a promoção de uma saúde integral em nossa sociedade.
Este livro pretende não apenas informar, mas também inspirar uma prática de saúde mais consciente e eficaz. Esperamos que os leitores encontrem neste trabalho um recurso valioso para aprimorar suas práticas e aprofundar sua compreensão sobre a saúde integral no século XXI.
A divulgação dos trabalhos acadêmicos e pesquisas em saúde desempenha um papel fundamental para profissionais da saúde, pesquisadores e demais leitores. Este processo não só valoriza o esforço intelectual investido, como também contribui para o avanço do conhecimento e a melhoria das práticas de saúde. A seguir, destacamos a importância da divulgação desses trabalhos:
Efectos de la transformación digital en el sector contable y financiero en Ecuador
Authors: Ocampo Alvarado Andrés Marcelo
Published: August 2024

La presente investigación tuvo como objetivo analizar los efectos de la transformación digital en el sector contable y financiero en Ecuador. Para lograr este objetivo se establecieron tres objetivos específicos, que fueron: identificar los cambios que la transformación digital ha generado en los procesos contables y financieros en empresas ecuatorianas de diversos sectores industriales, analizar las percepciones de los contadores y financieros sobre la adopción de tecnologías digitales en sus tareas cotidianas y cómo afecta a su desempeño laboral, y evaluar la efectividad de las soluciones tecnológicas implementadas en el sector contable y financiero en Ecuador, en términos de eficiencia, reducción de costos y mejora en la toma de decisiones. Para llevar a cabo esta investigación se utilizó un diseño de investigación no experimental de tipo transversal y se aplicó un cuestionario a 150 contadores y financieros de diferentes empresas de Ecuador. Los resultados de la investigación indican que la transformación digital ha tenido un impacto positivo en el sector contable y financiero en Ecuador, ya que ha permitido una mayor eficiencia en los procesos, reducción de costos y mejora en la toma de decisiones. Asimismo, los contadores y financieros perciben que la adopción de tecnologías digitales en sus tareas cotidianas ha mejorado su desempeño laboral y les ha permitido enfocarse en tareas más estratégicas. En cuanto a las soluciones tecnológicas implementadas en el sector contable y financiero, se encontró que las más utilizadas son el software de contabilidad y finanzas, los sistemas de gestión de recursos empresariales y los sistemas de gestión documental. Estas soluciones han demostrado ser efectivas en la mejora de los procesos y en la reducción de costos.
Exportaciones no tradicionales del sector alimenticio y crecimiento económico de Paraguay (2011-2020)
Authors: Cabral López María Antonella , Vera Zárate Rocío Alejandra
Published: August 2024

Las exportaciones de un país son clave para su economía. El objetivo de esta investigación es indagar sobre la contribución de las exportaciones no tradicionales al crecimiento económico del Paraguay a través del caso del sector alimenticio, durante el periodo 2011-2020. Para tal efecto, se planteó un diseño metodológico bibliográfico-documental, en el que se recurrió a un modelo econométrico que vinculaba el Producto Interno Bruto con las exportaciones tradicionales y no tradicionales del sector alimenticio junto con otras variables, para verificar sus efectos. Entre los principales resultados cabe señalar el efecto positivo de las exportaciones no tradicionales en el crecimiento de la economía y su potencial para diversificar la canasta exportadora del país.
Use of starch and actived tigernut by-product from the extraction of tigernut (Cyperus esculentus) milk for the purification of used cooking oils
Authors: Bou NDIAYE  , El Hadji Moussa DIOP  , Khadim NIANE  , Mohamed NDOYE  , Edouard Mbarick Ndiaye  , Samba BALDE  , Nicolas C. M. AYESSOU
Published: August 2024

The management of used cooking oils represents a real economic and environmental challenges. The search for bioadsorbents allows for the pre-treatment of used oils suitable for reuse. Tigernuts starch and by-product from the extraction of tigernut milk are used as bioadsorbent in the purification of used oil. The objective of this study is to reduce the acid and peroxide values. Used oil is treated with 8 and 12% starch during 10, 20, 30 and 40 min heating. Activated by-product were used as adsorbent at 1 and 2% after adsorption with starch. The results show abatement rates ranging from 1.65 to 27.51% for the acid value and from 39.16 to 73.48% for the peroxide value for 8% starch. Reductions rate of 23.50 to 34.44% and 58.06 to 71.33% respectively for the acid and peroxide values during treatment with 12% starch. The oil pre-treated with 8% starch shows an acid number reduction from 28.58 to 38.40% with 1% residue. Peroxide value shows reductions of 75.74 to 80.15% with 1% residue and 77.37 to 80.66% with 2% residue. The pre-treatment with 12% starch shows an acid value reduction ranging from 27.88 to 49.01% and from 14.0 to 35.08% with 1 and 2% residues. The peroxide value abatement ranges from 60.26 to 85.12% and from 77.37 to 87.33% with 1 and 2% residues. Tigernut starch can be used to purify used frying oils. However, its effectiveness is seen more in reducing the peroxide value. The combination of activated by-product and starch is more effective.
Development of a model for estimating the biomass of pastures using normalized difference vegetation index (NDVI): the case of the Niassa pastoral zone in Burkina Faso
Authors: Ghislain Tontibomma BAMBARA  , André KIEMA  , Valérie M.C. BOUGOUMA-YAMEOGO  , Abroulaye SANFO  , Wièmè SOME
Published: August 2024

In Burkina Faso, livestock feeding is based on pasture productivity, which is a key factor in managing livestock productivity. As such, this management requires a good knowledge of pastures. However, the high cost of producing pasture data and the inaccessibility of pastures due to insecurity mean that there is a low availability or lack of data on pasture. This makes it difficult for stakeholders to take decisions to improve livestock feed in the event of a local food crisis. This is why this study aims to facilitate data production by developing a model for estimating herbaceous biomass in pastures using land observation tools. To this end, the study correlated biomass data collected on the ground with satellite imagery. A total of 24 the wooded, shrubby, and grassy savannahs and gallery forests vegetation units were used as ground observation stations. Simple multilinear regression was chosen for the correlation test. The model parameters gave an R² of 0.70, an RMSE of 236.7 kg DM/ha with a p-value of less than 0.0001 and an average production of 1,423 kg DM/ha. Based on these parameters, there is a strong relationship between vegetation indices and pasture biomass. The equation Y=45*Vav+9*Vmx-19*Rrg-2,256 derived from the model can be used to estimate pasture herbaceous biomass. This will improve the availability of data on pasture forage resources for better action planning in a context of insecurity.
Utilizing an Artificial Neural Network with Limited Meteorological Data in AL-Fallujah City to Estimate AOD550 with MODIS AODs
Authors: Ahmed Yousif Ismael  , Abdel-Radi Abdel-Rahman Abdel-Qader  , Abdul Rahim Bashir Hamed Bashir
Published: August 2024

The amount of solar radiation that is absorbed by particles in the atmosphere is measured by the Aerosol Optical Depth (AOD550). Determining the precise role of aerosols requires an understanding of the fluctuations in worldwide AOD550. A neural network (ANN) model was created in AL-Fallujah, Iraq, with the purpose of training and estimating daily (AOD550). The statistical parameters Root Mean Square Error (RMSE), which are dependent on the correlation coefficient (R), and standard division (SD) were established to assess the produced ANN-models. For both the hidden and output layers, the activation functions (Segmiont, Gaussean, Hyperbolic Tangent, Hyperbolic Secant), hidden layers (1, 2, 3, and 4), and changes ranging from 10000 to 60000 with a 10000 interval were used. The created artificial neural network models were examined based on statistical criteria that were computed. ANN model (25) is found to be the best among all the models that were studied. Their corresponding (R) and (RMSE) values for the estimate phases were 0.939, 0.962, and 0.055, 4.3. These results show the generalization ability and full efficacy of the ANN model in pollution assessments.
Advancements in solvent extraction of metal ions: Mechanisms, kinetics, and efficiency with diverse extractants
Authors: Muhammad Saidur Rahman
Published: August 2024

This study illustrates the most recent developments and evolution of solvent extraction techniques for metal ion separation. It emphasizes the replacement of conventional extractants, such as TBP and β-diketones, with modern ones, including LIX reagents, D2EHPA, TOPO, and Cyanex reagents, as a result of enhanced design and process optimization. Recent research has demonstrated the efficacy of novel extractants in selectively targeting metal ions from complex matrices, illustrating the continuous advancements in solvent extraction techniques. In hydrometallurgy, solvent extraction is essential for the recovery, purification, and separation of both high-value and low-value metals. The review examines the history, principles, and applications of solvent extraction, with a particular emphasis on the mechanism of metal ion transfer and the characteristics of extractants such as Cyanex 272. It includes research on Mn(II) and Ni(II), as well as extractants' physicochemical properties and efficacy in selective separations. Additionally, it addresses extraction kinetics. The research also investigates surfactant properties, ligand exchange processes, and interfacial phenomena, all of which contribute to the development of environmentally benign metal extraction methods. Furthermore, it analyzes the commercial and selective separation value of extractants such as Cyanex 272, the limitations of traditional methods, the necessity for inventive alternatives, as well as historical innovations. The versatility and ongoing significance of solvent extraction in hydrometallurgical technology are underscored by mechanistic studies, which improve our comprehension of the stability constants and extraction behaviors of Mn(II) and Ni(II).
A comprehensive review of molybdenum nanomaterials
Authors: Liny P  , Jagadish H Patil
Published: August 2024

In the past few decades, there have been significant developments in nanotechnology in various areas. The present review focuses on the Molybdenum-based nanomaterials which have shown promising applications in the field of electronic and energy storage devices due to their tunable bandgaps, strong interaction with light. Molybdenum nanomaterials have characteristics next to graphene nanomaterials. Nano-scale forms of molybdenum oxide and molybdenum sulfide are excellent materials for supercapacitor electrodes. They exhibit high carrier mobility and optical transparency, which are considered to be the development of photodetectors. The review indicates different methods preferred for the synthesis of molybdenum-based nanomaterials and focuses on Molybdenum nanomaterials for electronic and energy storage devices.
Faktor-Faktor Yang Mempengaruhi Minat Siswa SMA Untuk Melanjutkan Pendidikan Ke Perguruan Tinggi dengan Latent Class Regression Analysis
Authors: Sinaga Melly Nia Fajriani , Dur Sajaratud , Cipta Hendra
Published: August 2024

Interest is an internal component within an individual that greatly influences his actions. Education is the process of changing the attitudes and behavior of a person or group in an effort to mature a person through teaching or training. The aim of this research is to determine the factors that influence high school students' interest in continuing their education to higher education using the latent class regression analysis method. The latent class regression analysis method can determine the influence of accompanying variables or covariates in the formation of latent classes. The most dominant factors influencing high school students' interest in continuing their education to higher education are needs, facilities and attention. In the first class the influencing factor is need. In the second and third classes the influencing factor is facilities. In the fourth class the influencing factor is attention.
Implementasi Game Theory Dalam Penentuan Strategi Bersaing Pada Produk Sepeda Motor
Authors: Wahyudi Ahmad , Sari Rina Widya , Harleni Silvia
Published: August 2024

Competition in the business world, especially land transportation equipment, is currently getting tighter with its use in people's lives, one of which is motorbikes. Its use is very easy and very helpful in everyday life, causing many people to be interested in it. This research aims to determine competitive strategies in motorbike product competition by applying mathematical methods, namely Game Theory. The research results obtained show competition between Honda motorbike products and Yamaha motorbike products with Honda's optimal strategy being product quality, while the optimal strategy for Yamaha motorbike products to compete with Honda motorbike products is model and spare parts.
Motivasi Belajar Matematika Menurut Neurosains bagi Siswa Kelas VIII SMP Kanisius Gayam Yogyakarta
Authors: Maharani Wayan , Tiara Gunawan Monica , Andy Rudhito Marcellinus
Published: August 2024

Pada pembelajaran matematika masih terdapat siswa yang memiliki motivasi belajar yang rendah. Hal ini berpengaruh kepada kemampuan matematika yang dimiliki oleh siswa.  Penelitian ini memiliki tujuan mengetahui tingkat motivasi belajar matematika yang dipandang dari neurosains. Subjek dalam penelitian ini adalah 30 siswa kelas VIII D SMP Kanisius Gayam Yogyakarta Tahun Ajaran 2023/2024. Penelitian ini merupakan penelitian kualitatif deskriptif yang menggunakan metode penggumpulan data dengan kuisioner. Adapun instrumen yang digunakan untuk memperoleh data adalah lembar kuisioner. Hasil dari penelitian ini menunjukkan motivasi tipe A masuk dalam kategori tinggi mendapat rata-rata nilai 69, tipe B masuk dalam kategori tinggi mendapat rata-rata nilai 67,6, tipe C masuk dalam kategori tinggi mendapat rata-rata nilai 62,5 dan tipe X masuk dalam kategori cukup mendapat rata-rata nilai 60,33. Secara keseluruhan rata-rata nilai keempat tipe motivasi tersebut masuk dalam kategori tinggi.
Solusi Masalah Bullying Menggunakan Pemodelan Matematika dengan Bimbingan dan Kounseling pada Pelajar Madrasah di Kabupaten Gowa
Authors: Aisyah Zahra Ramadhani Asya  , Damang Dahnial , Side Syafruddin , Muhammad Ridho Yusuf SAP  , Pratama Muhammad Isbar
Published: August 2024

Penelitian ini mengkaji tentang solusi permasalahan bullying menggunakan pemodelan matematika dengan Bimbingan Konseling pada Pelajar Madrasah di Kabupaten Gowa. Tujuan penelitian ini adalah membangun model matematika SBP yang menggambarkan laju Perilaku kasus sosial pembulyan, menganalisis model bullying, mendapatkan solusi bullying dengan bimbingan konseling. Penelitian ini menggunakan pendekatan kuantitatif, populasi penelitian adalah siswa-siswi Madrasah Tsanawiyah (MTs) dan Madrasah Aliyah (MA) di Kabupaten Gowa sebanyak 10.463 orang. Jumlah sampel sebanyak 362 orang sebagai data utama penelitian yang diperoleh melalui instrument dan kuesioner secara luring dan daring. Penelitian dimulai dengan membagun model matematika kasus bullying, menganalisis model dan simulasi model berdasarkan data riil untuk menyimpulkan solusi pembulyan dengan bimbingan dan konseling di Madrasah menggunakan Maple. Hasil penelitian menunjukkan bahwa hasil sintetis analisis dan simulasi model matematika SBP mengungkapkan dua titik keseimbangan yaitu keseimbangan yang tidak bebas dan bebas dari perilaku kasus sosial pembulyan, hasil simulasi menunjukkan bahwa kasus pembulyan akan selalu ada di kalangan pelajar di MTs dan MA, tetapi nilai bilangan reproduksi dasar R0=0,74889 yang mengindikasikan bahwa proses pembulyang dapat diatasi dan tidak terjadi penyebaran secara psikologi dimana setiap pelajar yang mendapatkan kasus dibuly tidak mempengaruhi pelajar lainnya dengan memaksimalkan bimbingan dan konseling di Madrasah. Hasil penelitian ini dapat menjadi rujukan bagi sekolah-sekolah yang ada di Indonesia.
Analysis of Students' Critical Thinking Skill in Terms of Visualizer and Verbalizer Cognitive Styles in Factoring Quadratic Equations
Authors: Arwadi Fajar , Sabri Sabri , Shalihin Shafwan
Published: August 2024

Penelitian ini bertujuan untuk mengetahui bagaimana kemampuan berpikir kritis siswa dalam menyelesaikan pemfktoran persamaan kuadrat yang ditinjau dari gaya kognitif visualizer dan verbalizer. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan skema yang terdiri sdari dua tahap yaitu: (1) mengidentifikasi jenis gaya kognitif siswa ke dalam dua jenis visualizer atau verbalizer; selanjutnya melakukan analisis terhadap kemampuan berpikir kritis siswa berdasarkan indikator yang telah ditetapkan. Penelitian ini dilaksanakan di UPT SPF SMP Negeri 19 pada 30 siswa kelas IX A. Instrumen yang digunakan dalam penelitian ini visualizer-verbalizer questionnaire, tes penyelesaian masalah terkait pemfaktoran persamaan kuadrat, dan pedoman wawancara. Hasil penelitian menunjukkan bahwa.
Integrasi Penerapan Model Problem Based Learning (PBL) dengan Model Pembelajaran Connecting, Organizing, Reflecting, Extending (CORE) terhadap Kemampuan Pemecahan Masalah Matematika Calon Guru SD
Authors: Latri Latri , Juhari Agusalim , Patta Rahmawati
Published: August 2024

This research aims to explain the effectiveness of integrating the PBL model with the CORE model on the mathematical problem solving abilities of prospective elementary school teachers. Pre-experimental research with One-Group Pretest Posttest Design to achieve research objectives. The population in this study were all PGSD students at Makassar State University consisting of 3 classes. The experimental units were taken using cluster random sampling, from 3 selected classes, namely BC.212 as the experimental class consisting of 30 people. The data collection techniques used were learning outcomes tests, observation sheets, and student response questionnaires. Student activity and response data were analyzed using descriptive statistical analysis, while student mathematics learning outcomes data used inferential statistical analysis. The results of the research show that the integration of the PBL model with the CORE model is effectively applied in mathematics learning, Geometry and Learning material in terms of: 1) the average score of mathematics learning outcomes in the aspect of students' Problem Solving Ability in the posttest is greater than 75 (KKM), namely 83, 4 of the ideal scores of 100 are in the High category. The normalized gain obtained is 0.73, which is in the High classification; 2) the average student activity score of 3.56 is in the very active category; 4) the average percentage of student responses was 85.45% in the positive category.