bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from Regulation of CD4+NKG2D+ Th1 Cells in Patients with Metastatic Melanoma Treated with Sorafenib: Role of IL-15Rα and NKG2D Triggering
Authors: Romero Ana I. , Chaput Nathalie , Poirier-Colame Vichnou , Rusakiewicz Sylvie , Jacquelot Nicolas , Chaba Kariman , Mortier Erwan , Jacques Yannick , Caillat-Zucman Sophie , Flament Caroline , Caignard Anne , Messaoudene Meriem , Aupérin Anne , Vielh Philippe , Dessen Philippe , Porta Camillo , Mateus Christine , Ayyoub Maha , Valmori Danila , Eggermont Alexander , Robert Caroline , Zitvogel Laurence
Published: April 2023

PDF file - 38K, Synergistic effects of TCR or IL-15 stimulation with NKG2D engagement for Th1 polarization in CD4+NKG2D+T cells.
Supplementary Figure 8 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases
Authors: von Scheidt Bianca , Leung Patrick S.K. , Yong Michelle C.R. , Zhang Yu , Towne Jennifer E. , Smyth Mark J. , Teng Michele W.L.
Published: April 2023

PDF file - 59K, Detection of IL-23 in ex vivo isolated peritoneal exudate cells, liver mononuclear cells following LPS stimulation.
Data Supplement from Optimal Effector Functions in Human Natural Killer Cells Rely upon Autocrine Bone Morphogenetic Protein Signaling
Authors: Robson Neil C. , Hidalgo Laura , McAlpine Tristan , Wei Heng , Martínez Víctor G. , Entrena Ana , Melen Gustavo J. , MacDonald Andrew S. , Phythian-Adams Alexander , Sacedón Rosa , Maraskovsky Eugene , Cebon Jonathan , Ramírez Manuel , Vicente Angeles , Varas Alberto
Published: April 2023

Supplemental Figure S1. BMP pathway gene expression in activated NK cells.
Data Supplement from Optimal Effector Functions in Human Natural Killer Cells Rely upon Autocrine Bone Morphogenetic Protein Signaling
Authors: Robson Neil C. , Hidalgo Laura , McAlpine Tristan , Wei Heng , Martínez Víctor G. , Entrena Ana , Melen Gustavo J. , MacDonald Andrew S. , Phythian-Adams Alexander , Sacedón Rosa , Maraskovsky Eugene , Cebon Jonathan , Ramírez Manuel , Vicente Angeles , Varas Alberto
Published: April 2023

Supplemental Figure S2. Intracellular BMPRIA and p-Smad-1/-5/-8 expression by CD56int and CD56hi NK cells.
Supplementary Figure 1 from RSF1 Is a Positive Regulator of NF-κB–Induced Gene Expression Required for Ovarian Cancer Chemoresistance
Authors: Yang Yeong-In , Ahn Ji-Hye , Lee Kyung-Tae , Shih Ie-Ming , Choi Jung-Hye
Published: April 2023

PDF file - 80KB, Effect of the combination of paclitaxel treatment and RSF1 silencing on tumor weight and body weight in ovarian cancer xenograft mice.
Supplementary Movie 1 from An Integrated Computational Model of the Bone Microenvironment in Bone-Metastatic Prostate Cancer
Authors: Araujo Arturo , Cook Leah M. , Lynch Conor C. , Basanta David
Published: April 2023

Normal bone remodeling.
Supplementary Movie 4 from Curcumin Targets Breast Cancer Stem–like Cells with Microtentacles That Persist in Mammospheres and Promote Reattachment
Authors: Charpentier Monica S. , Whipple Rebecca A. , Vitolo Michele I. , Boggs Amanda E. , Slovic Jana , Thompson Keyata N. , Bhandary Lekhana , Martin Stuart S.
Published: April 2023

MOV file - 1782K, Live cell confocal imaging of BT-549 mammosphere stained with CellMask Orange (red) and transduced with GFP-membrane (green) suspended over a glass surface. Three-dimensional computer-rendered image reveals McTNs from the GFP-membrane cell encircling other cells in the mammosphere.
Supplementary Figure Legends from Cancer Cells Exploit eIF4E2-Directed Synthesis of Hypoxia Response Proteins to Drive Tumor Progression
Authors: Uniacke James , Kishan Perera J. , Lachance Gabriel , Francisco Camille B. , Lee Stephen
Published: April 2023

PDF file - 88K
Supplementary Figure Legends from A Rare Polymorphic Variant of NBS1 Reduces DNA Repair Activity and Elevates Chromosomal Instability
Authors: Yamamoto Yuki , Miyamoto Mamiko , Tatsuda Daisuke , Kubo Michiaki , Nakagama Hitoshi , Nakamura Yusuke , Satoh Hitoshi , Matsuda Koichi , Watanabe Toshiki , Ohta Tsutomu
Published: April 2023

PDF file - 408KB
Supplementary Figure 5 from Cancer Cells Exploit eIF4E2-Directed Synthesis of Hypoxia Response Proteins to Drive Tumor Progression
Authors: Uniacke James , Kishan Perera J. , Lachance Gabriel , Francisco Camille B. , Lee Stephen
Published: April 2023

PDF file - 705K, eIF4E2 loss prevents tumor growth and reduces the growth of already-established tumors.
Supplementary Figure 8 from A Rare Polymorphic Variant of NBS1 Reduces DNA Repair Activity and Elevates Chromosomal Instability
Authors: Yamamoto Yuki , Miyamoto Mamiko , Tatsuda Daisuke , Kubo Michiaki , Nakagama Hitoshi , Nakamura Yusuke , Satoh Hitoshi , Matsuda Koichi , Watanabe Toshiki , Ohta Tsutomu
Published: April 2023

PDF file - 13KB, The NBS1-I171V polymorphic variant exerted a dominant-negative effect on wild-type NBS1 elevated chromosomal instability.
Supplementary Figure 3 from Cancer Cells Exploit eIF4E2-Directed Synthesis of Hypoxia Response Proteins to Drive Tumor Progression
Authors: Uniacke James , Kishan Perera J. , Lachance Gabriel , Francisco Camille B. , Lee Stephen
Published: April 2023

PDF file - 797K, Cancer cells require eIF4E2-directed protein synthesis to evade cell death.
Supplementary Figure 1 from Cancer Cells Exploit eIF4E2-Directed Synthesis of Hypoxia Response Proteins to Drive Tumor Progression
Authors: Uniacke James , Kishan Perera J. , Lachance Gabriel , Francisco Camille B. , Lee Stephen
Published: April 2023

PDF file - 805K, Spheroids and xenografts contain hypoxic cores with inactive mTORC1.
Supplementary Figure Legend from Metastasis Suppressor KISS1 Seems to Reverse the Warburg Effect by Enhancing Mitochondrial Biogenesis
Authors: Liu Wen , Beck Benjamin H. , Vaidya Kedar S. , Nash Kevin T. , Feeley Kyle P. , Ballinger Scott W. , Pounds Keke M. , Denning Warren L. , Diers Anne R. , Landar Aimee , Dhar Animesh , Iwakuma Tomoo , Welch Danny R.
Published: April 2023

PDF file - 65K
Supplementary Table 2 from Attenuation of microRNA-126 Expression That Drives CD34+38− Stem/Progenitor Cells in Acute Myeloid Leukemia Leads to Tumor Eradication
Authors: de Leeuw David C. , Denkers Fedor , Olthof Marjolein C. , Rutten Arjo P. , Pouwels Walter , Jan Schuurhuis Gerrit , Ossenkoppele Gert J. , Smit Linda
Published: April 2023

XLSX file - 14KB, MicroRNAs differentially expressed between LSC and progenitors (at least 4 out of 6 patients): Upper: MicroRNA expression ratios between CD34+CD38-ALDHlow/dim (LSC) and CD34+CD38+ALDHlow/dim (malignant progenitor) populations obtained from microarray analysis. The average ratio is calculated over all 6 patients. Number of patients indicate the number of patients that show significant differential expression for that microRNA. Lower: Average and standard deviations of all ratios between LSC and malignant progenitors per patient. 'Average + Stdev' and 'Average - Stdev', average plus or minus one time the standard deviation for each individual patient indicate the values used as cutoff for significant microRNAs per patients. Italic printed ratios represent non-significant microRNAs for that individual patient.
Supplementary Figures 1 - 7 from Intratumoral Modeling of Gefitinib Pharmacokinetics and Pharmacodynamics in an Orthotopic Mouse Model of Glioblastoma
Authors: Sharma Jyoti , Lv Hua , Gallo James M.
Published: April 2023

PDF file - 511K, Figure S1: Trend in regional gefitinib PK/PD in U87vIII brain tumors following a single dose of 150 mg/kg gefitinib orally. Figure S2: Trend in regional gefitinib PK/PD in U87VIII brain tumors following a single dose of 50 mg/kg gefitinib orally. Figure S3: Intratumoral immunohistochemical analysis of MPI and MTI in U87vIII brain tumors following single doses of 50 mg/kg gefitinib orally. Figure S4: Intratumoral PD modeling of gefitinib in athymic mice bearing intracerebral U87vIII tumors following either 50 mg/kg or 150 mg/kg single oral doses. Figure S5 : Effect of gefitinib on pERK and pAKT protein levels in U87vIII glioma cells as a function of drug concentration. Figure S6: Diagostic plots (model-predicted vs observed gefitinib concetrations and model-predicted gefitinib concentrations vs residuals) for brain tumor PK model. Figure S7: Diagostic plots (model-predicted vs observed fraction of baseline pERK and model-predicted fraction of baseline pERK vs residuals) for tumor PD model.
Supplementary Figure Legends from Mesenchymal Stem Cells Use IDO to Regulate Immunity in Tumor Microenvironment
Authors: Ling Weifang , Zhang Jimin , Yuan Zengrong , Ren Guangwen , Zhang Liying , Chen Xiaodong , Rabson Arnold B. , Roberts Arthur I. , Wang Ying , Shi Yufang
Published: April 2023

PDF file - 97KB
Supplementary Figure 7 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Authors: Doherty Joanne R. , Yang Chunying , Scott Kristen E.N. , Cameron Michael D. , Fallahi Mohammad , Li Weimin , Hall Mark A. , Amelio Antonio L. , Mishra Jitendra K. , Li Fangzheng , Tortosa Mariola , Genau Heide Marika , Rounbehler Robert J. , Lu Yunqi , Dang Chi V. , Kumar K. Ganesh , Butler Andrew A. , Bannister Thomas D. , Hooper Andrea T. , Unsal-Kacmaz Keziban , Roush William R. , Cleveland John L.
Published: April 2023

PDF file - 728K, Immunohistochemistry analyses of MCT1 and MCT4, and survival and tumor analyses of Raji lymphoma and T47D breast cancer cell xenografts.
Supplementary Figure 6 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Authors: Doherty Joanne R. , Yang Chunying , Scott Kristen E.N. , Cameron Michael D. , Fallahi Mohammad , Li Weimin , Hall Mark A. , Amelio Antonio L. , Mishra Jitendra K. , Li Fangzheng , Tortosa Mariola , Genau Heide Marika , Rounbehler Robert J. , Lu Yunqi , Dang Chi V. , Kumar K. Ganesh , Butler Andrew A. , Bannister Thomas D. , Hooper Andrea T. , Unsal-Kacmaz Keziban , Roush William R. , Cleveland John L.
Published: April 2023

PDF file - 78K, Effects of combined treatment of SR13800 and metformin on intracellular lactate and proliferation of Raji BL cells, and upon the proliferation of MCT1-expressing lymphoma and breast cancer cells.
Supplementary Figure 5 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Authors: Doherty Joanne R. , Yang Chunying , Scott Kristen E.N. , Cameron Michael D. , Fallahi Mohammad , Li Weimin , Hall Mark A. , Amelio Antonio L. , Mishra Jitendra K. , Li Fangzheng , Tortosa Mariola , Genau Heide Marika , Rounbehler Robert J. , Lu Yunqi , Dang Chi V. , Kumar K. Ganesh , Butler Andrew A. , Bannister Thomas D. , Hooper Andrea T. , Unsal-Kacmaz Keziban , Roush William R. , Cleveland John L.
Published: April 2023

PDF file - 142K, MCT1 inhibition blocks glycolysis in Burkitt lymphoma cells, without affecting the steady state levels of glycolytic enzymes. Schematic of glutathione (GSH) metabolism and levels of components of glutamylcysteine ligase (GCL) in Raji BL cells treated with SR13800.
Supplementary Table 1 from PP2A-B55β Antagonizes Cyclin E1 Proteolysis and Promotes Its Dysregulation in Cancer
Authors: Tan YingMeei , Sun Dahui , Jiang Weijian , Klotz-Noack Kathleen , Vashisht Ajay A. , Wohlschlegel James , Widschwendter Martin , Spruck Charles
Published: April 2023

PDF file - 48KB, Clinicopathological features of breast cancers analyzed for cyclin E1 protein, and CCNE1 and B55beta expression.
Supplementary Figure 2 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Authors: Doherty Joanne R. , Yang Chunying , Scott Kristen E.N. , Cameron Michael D. , Fallahi Mohammad , Li Weimin , Hall Mark A. , Amelio Antonio L. , Mishra Jitendra K. , Li Fangzheng , Tortosa Mariola , Genau Heide Marika , Rounbehler Robert J. , Lu Yunqi , Dang Chi V. , Kumar K. Ganesh , Butler Andrew A. , Bannister Thomas D. , Hooper Andrea T. , Unsal-Kacmaz Keziban , Roush William R. , Cleveland John L.
Published: April 2023

PDF file - 366K, MYC, MCT1, MCT2, MCT3 and MCT4 mRNA levels in human tumors and survival analysis of human breast and lung cancer patients expressing high levels of both MYC and MCT1.
Supplementary Figure 1 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Authors: Doherty Joanne R. , Yang Chunying , Scott Kristen E.N. , Cameron Michael D. , Fallahi Mohammad , Li Weimin , Hall Mark A. , Amelio Antonio L. , Mishra Jitendra K. , Li Fangzheng , Tortosa Mariola , Genau Heide Marika , Rounbehler Robert J. , Lu Yunqi , Dang Chi V. , Kumar K. Ganesh , Butler Andrew A. , Bannister Thomas D. , Hooper Andrea T. , Unsal-Kacmaz Keziban , Roush William R. , Cleveland John L.
Published: April 2023

PDF file - 249K, Expression analysis of glycolytic genes in EMu-Myc B cells and lymphoma versus wild type B cells.
Supplementary Figure 4 from PP2A-B55β Antagonizes Cyclin E1 Proteolysis and Promotes Its Dysregulation in Cancer
Authors: Tan YingMeei , Sun Dahui , Jiang Weijian , Klotz-Noack Kathleen , Vashisht Ajay A. , Wohlschlegel James , Widschwendter Martin , Spruck Charles
Published: April 2023

PDF file - 84KB, Cyclin E1 protein levels do not correlate with B56beta (A), B56delta (B), or Fbxw7alpha (C) expression in breast cancers. Fresh-frozen breast cancer specimens were analyzed for cyclin E1 protein by Western blotting and B56beta, B56delta, Fbxw7alpha mRNA by qPCR. Linear regression analysis was used to identify possible correlations.
Supplementary Figure 1 from Chromosome 10, Frequently Lost in Human Melanoma, Encodes Multiple Tumor-Suppressive Functions
Authors: Kwong Lawrence N. , Chin Lynda
Published: April 2023

PDF file - 328KB, Correlation of DNA copy number aberrations to survival statistics.
Supplementary Table 5 from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
Authors: Goc Jérémy , Germain Claire , Vo-Bourgais Thi Kim Duy , Lupo Audrey , Klein Christophe , Knockaert Samantha , de Chaisemartin Luc , Ouakrim Hanane , Becht Etienne , Alifano Marco , Validire Pierre , Remark Romain , Hammond Scott A. , Cremer Isabelle , Damotte Diane , Fridman Wolf-Herman , Sautès-Fridman Catherine , Dieu-Nosjean Marie-Caroline
Published: April 2023

PDF file - 168K, Gene expression on tumors stratified according to the high/low density of DC-Lamp+ mature DC.
Supplementary Figure Legend from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
Authors: Goc Jérémy , Germain Claire , Vo-Bourgais Thi Kim Duy , Lupo Audrey , Klein Christophe , Knockaert Samantha , de Chaisemartin Luc , Ouakrim Hanane , Becht Etienne , Alifano Marco , Validire Pierre , Remark Romain , Hammond Scott A. , Cremer Isabelle , Damotte Diane , Fridman Wolf-Herman , Sautès-Fridman Catherine , Dieu-Nosjean Marie-Caroline
Published: April 2023

PDF file - 115K
Supplementary Figure 6 from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
Authors: Goc Jérémy , Germain Claire , Vo-Bourgais Thi Kim Duy , Lupo Audrey , Klein Christophe , Knockaert Samantha , de Chaisemartin Luc , Ouakrim Hanane , Becht Etienne , Alifano Marco , Validire Pierre , Remark Romain , Hammond Scott A. , Cremer Isabelle , Damotte Diane , Fridman Wolf-Herman , Sautès-Fridman Catherine , Dieu-Nosjean Marie-Caroline
Published: April 2023

PDF file - 151K, Expression on tumor-infiltrating T cells of molecules involved in cytotoxicity, activation, and Th1 orientation.
Supplementary Figure S2 from Adiponectin Receptor Signaling on Dendritic Cells Blunts Antitumor Immunity
Authors: Tan Peng H. , Tyrrell Helen E.J. , Gao Liquan , Xu Danmei , Quan Jianchao , Gill Dipender , Rai Lena , Ding Yunchuan , Plant Gareth , Chen Yuan , Xue John Z. , Handa Ashok I. , Greenall Michael J. , Walsh Kenneth , Xue Shao-An
Published: April 2023

Adiponectin (APN) arrests dendritic cells in an immature state by inhibiting NFkB to induce T cell anergy.
Supplementary Figures 1 - 6 from B-cell Expansion and Lymphomagenesis Induced by Chronic CD40 Signaling Is Strictly Dependent on CD19
Authors: Hojer Caroline , Frankenberger Samantha , Strobl Lothar J. , Feicht Samantha , Djermanovic Kristina , Jagdhuber Franziska , Hömig-Hölzel Cornelia , Ferch Uta , Ruland Jürgen , Rajewsky Klaus , Zimber-Strobl Ursula
Published: April 2023

PDF file - 364K, Suppl. Figure 1. BM B cell development is comparable in LMP1/CD40//CD19+/- and LMP1/CD40//CD19-/- mice. Suppl. Figure 2. CD40 employs CD19 to mediate survival signals. Suppl. Figure 3. Loss of CD19 abrogates lymphoma development in LMP1/CD40 mice. Suppl. Figure 4A. Stimulation of B cells with anti-IgM in the presence of Dasatinib. Suppl. Figure 4B. Titration of the PI3K inhibitor LY294004 Suppl. Figure 5A. Sorafenib does not affect Erk phosphorylation in LMP1/CD40+ B cells. Suppl. Figure 5B. CD19 expression on different DLBCL and HL cell lines. Suppl. Figure 6A. CD40 expression in different DLBCL cell lines. Suppl. Figure 6B. CD19 phosphorylation after stimulation with a CD40 ligand.
Supplementary Figure 4 from Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma
Authors: Tahara Tomomitsu , Yamamoto Eiichiro , Suzuki Hiromu , Maruyama Reo , Chung Woonbok , Garriga Judith , Jelinek Jaroslav , Yamano Hiro-o , Sugai Tamotsu , An Byonggu , Shureiqi Imad , Toyota Minoru , Kondo Yutaka , Estécio Marcos R.H. , Issa Jean-Pierre J.
Published: April 2023

PDF file - 42K, DNA methylation status of 7 genes in 72 colonic biopsies from 65 cancer free subjects.
Supplementary Figure 1 from Alarmin IL-33 Acts as an Immunoadjuvant to Enhance Antigen-Specific Tumor Immunity
Authors: Villarreal Daniel O. , Wise Megan C. , Walters Jewell N. , Reuschel Emma L. , Choi Min Joung , Obeng-Adjei Nyamekye , Yan Jian , Morrow Matthew P. , Weiner David B.
Published: April 2023

PDF file - 50KB, Protective efficacy maintained by mtrIL-33- and proIL-33-adjuvanted ConE6E7. In a prophylactic study, groups of B6 (10 mice/group) were immunized (three times at three week intervals) with ConE6E7 with or without 7μg of mtrIL-33 or proIL-33 and challenged with 5x104 TC-1 cells one week after last immunization to assess the anti-tumor effects. All vaccination groups prevented tumor growth upon TC-1 implantation.
Supplementary Figure Legend from EGF Receptor Activates MET through MAPK to Enhance Non–Small Cell Lung Carcinoma Invasion and Brain Metastasis
Authors: Breindel Jerrica L. , Haskins Jonathan W. , Cowell Elizabeth P. , Zhao Minghui , Nguyen Don X. , Stern David F.
Published: April 2023

PDF file - 79K
Supplementary Figure 5 from VISTA Is an Immune Checkpoint Molecule for Human T Cells
Authors: Lines J. Louise , Pantazi Eirini , Mak Justin , Sempere Lorenzo F. , Wang Li , O'Connell Samuel , Ceeraz Sabrina , Suriawinata Arief A. , Yan Shaofeng , Ernstoff Marc S. , Noelle Randolph
Published: April 2023

PDF file - 77KB, VISTA does not affect B cell proliferation. CD19 positive B cells were purified from human PBMCs by magnetic bead negative selection. (a and b) cells were stimulated in the presence of VISTA-Ig (a) or control Ig (b) at 5ug/ml for 4 days with 250ng/ml of CD40 agonist. Plots show representative CFSE profiles gated on live CD19 positive events. C) percent proliferation in the presence of decreasing concentrations of agonist in the presence of VISTA-Ig (filled bars) or control Ig (open bars) at 5ug/ml for 4 days. Data is representative of 3 separate experiments.
Supplementary Figure 1 from HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells
Authors: Lal Shruti , Burkhart Richard A. , Beeharry Neil , Bhattacharjee Vikram , Londin Eric R. , Cozzitorto Joseph A. , Romeo Carmella , Jimbo Masaya , Norris Zoë A. , Yeo Charles J. , Sawicki Janet A. , Winter Jordan M. , Rigoutsos Isidore , Yen Timothy J. , Brody Jonathan R.
Published: April 2023

PDF file - 2204KB, Different DNA damaging agents activate HuR.
Supplementary Table 2B from shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer
Authors: Deng Tao , Liu Jeff C. , Chung Philip E.D. , Uehling David , Aman Ahmed , Joseph Babu , Ketela Troy , Jiang Zhe , Schachter Nathan F. , Rottapel Robert , Egan Sean E. , Al-awar Rima , Moffat Jason , Zacksenhaus Eldad
Published: April 2023

PDF file - 47KB, Supplementary Table S2a and S2b list hits on Her2/Neu spheres and monolayer cells.
Supplementary Figure 2 from Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer
Authors: Meeker Stacey , Seamons Audrey , Paik Jisun , Treuting Piper M. , Brabb Thea , Grady William M. , Maggio-Price Lillian
Published: April 2023

PDF file - 63K, High dietary vitamin D decreases diarrhea in H. bilis-infected Smad3-/- mice.
Supplementary Table 1 from Vaccine-Mediated Immunotherapy Directed against a Transcription Factor Driving the Metastatic Process
Authors: Ardiani Andressa , Gameiro Sofia R. , Palena Claudia , Hamilton Duane H. , Kwilas Anna , King Thomas H. , Schlom Jeffrey , Hodge James W.
Published: April 2023

PDF file - 208KB, Recombinant Yeast-Twist vaccination does not induce toxicity.
Supplementary Figure 1 from Vaccine-Mediated Immunotherapy Directed against a Transcription Factor Driving the Metastatic Process
Authors: Ardiani Andressa , Gameiro Sofia R. , Palena Claudia , Hamilton Duane H. , Kwilas Anna , King Thomas H. , Schlom Jeffrey , Hodge James W.
Published: April 2023

PDF file - 138KB, Expression of murine Twist protein in S. cerevisiae Yeast.
Supplementary Figure 2 from Loss of Androgen Receptor Expression Promotes a Stem-like Cell Phenotype in Prostate Cancer through STAT3 Signaling
Authors: Schroeder Anne , Herrmann Andreas , Cherryholmes Gregory , Kowolik Claudia , Buettner Ralf , Pal Sumanta , Yu Hua , Müller-Newen Gerhard , Jove Richard
Published: April 2023

PDF file - 5546K, Supplementary Fig.2: STAT3 activation is associated with upregulated CSC marker expression.
Supplementary Figure 1 from Novel Mechanism of MDA-7/IL-24 Cancer-Specific Apoptosis through SARI Induction
Authors: Dash Rupesh , Bhoopathi Praveen , Das Swadesh K. , Sarkar Siddik , Emdad Luni , Dasgupta Santanu , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 174K, S1. Expression of IL-20R1, IL-20R2 and IL-22R receptors in A549, DU-145 and HO-1 cells.
Supplementary Table 1 from Tumor-Derived GM-CSF Promotes Inflammatory Colon Carcinogenesis via Stimulating Epithelial Release of VEGF
Authors: Wang Yi , Han Gencheng , Wang Ke , Liu Guijun , Wang Renxi , Xiao He , Li Xinying , Hou Chunmei , Shen Beifen , Guo Renfeng , Li Yan , Chen Guojiang
Published: April 2023

PDF file - 171K, Primer list.
Supplementary Figure 1 from Netrin-1 Promotes Medulloblastoma Cell Invasiveness and Angiogenesis, and Demonstrates Elevated Expression in Tumor Tissue and Urine of Patients with Pediatric Medulloblastoma
Authors: Akino Tomoshige , Han Xuezhe , Nakayama Hironao , McNeish Brendan , Zurakowski David , Mammoto Akiko , Klagsbrun Michael , Smith Edward
Published: April 2023

PDF file - 89KB, Netrin-1 induces phosphorylation of Erk.
Supplementary Materials and Methods and Figure Legends from CBP Loss Cooperates with PTEN Haploinsufficiency to Drive Prostate Cancer: Implications for Epigenetic Therapy
Authors: Ding Liya , Chen Shuai , Liu Ping , Pan Yunqian , Zhong Jian , Regan Kevin M. , Wang Liguo , Yu Chunrong , Rizzardi Anthony , Cheng Liang , Zhang Jun , Schmechel Stephen C. , Cheville John C. , Van Deursen Jan , Tindall Donald J. , Huang Haojie
Published: April 2023

PDF file - 131KB
Supplementary Figure 2 from Bcl2 Induces DNA Replication Stress by Inhibiting Ribonucleotide Reductase
Authors: Xie Maohua , Yen Yun , Owonikoko Taofeek K. , Ramalingam Suresh S. , Khuri Fadlo R. , Curran Walter J. , Doetsch Paul W. , Deng Xingming
Published: April 2023

PDF file - 154K, Expression of Bcl2 retards DNA replication via reduction of deoxyribouclotide synthesis and RNR activity in normal human bronchial epithelial (BEAS-2B) cells.
Supporting Materials and Methods; Supporting References from Endothelin A Receptor/β-Arrestin Signaling to the Wnt Pathway Renders Ovarian Cancer Cells Resistant to Chemotherapy
Authors: Rosanò Laura , Cianfrocca Roberta , Tocci Piera , Spinella Francesca , Di Castro Valeriana , Caprara Valentina , Semprucci Elisa , Ferrandina Gabriella , Natali Pier Giorgio , Bagnato Anna
Published: April 2023

Supporting Materials and Methods; Supporting References
Supplementary Figures 1 - 2 from Curative Properties of Noninternalizing Antibody–Drug Conjugates Based on Maytansinoids
Authors: Perrino Elena , Steiner Martina , Krall Nikolaus , Bernardes Gonçalo J.L. , Pretto Francesca , Casi Giulio , Neri Dario
Published: April 2023

PDF file - 81KB, Supplementary figures 1: SDS-PAGE monitoring of stability of antibody drug conjugates in mouse serum and 2: tumor appearance.
Supplementary Table 1 from Germline Mutations in BAP1 Impair Its Function in DNA Double-Strand Break Repair
Authors: Ismail Ismail Hassan , Davidson Riley , Gagné Jean-Philippe , Xu Zhi Zhong , Poirier Guy G. , Hendzel Michael J.
Published: April 2023

PDF file - 46KB, Table S1: Effect of different pre-extraction procedures on BAP1 localization in cells after DNA damage. U2OS cells were left untreated or exposed to IR (2 Gy) or UV light for 2 min ( 60 J/min). Cells were allowed to recover for 1 hr before pre-extracted with different buffers as outlined in the above table. Cells were then fixed with 2% PFA and processed for immunostaining as described in the material and methods. Results are summarized in the above the table. CSK, cytoskelton buffer, CSK+R, CSK+ RNAase as described in JCB , 2013, vol. 202 no. 3 579-595, Buffer A, cells were pre-extracted as described in J Cell Biol 2009 187:977-990, Buffer B, cells were extracted as described in Mol. Cell. Biol. January 2001 vol. 21 no. 1 281-288.
Supplementary Figures 1 through 6 from The Transcriptional Regulatory Network of Proneural Glioma Determines the Genetic Alterations Selected during Tumor Progression
Authors: Sonabend Adam M. , Bansal Mukesh , Guarnieri Paolo , Lei Liang , Amendolara Benjamin , Soderquist Craig , Leung Richard , Yun Jonathan , Kennedy Benjamin , Sisti Julia , Bruce Samuel , Bruce Rachel , Shakya Reena , Ludwig Thomas , Rosenfeld Steven , Sims Peter A. , Bruce Jeffrey N. , Califano Andrea , Canoll Peter
Published: April 2023

PDF - 1816K, Supplementary Figure 1: CGH probe for Cre-mediated Pten deletion provides a surrogate of tumor DNA content for mouse tumors. Supplementary Figure 2: The genomic architecture of mouse tumor gene deletions suggests independent selection pressure for genes within the same deletion in human tumors. Supplementary Figure 3: Mouse and Human Proneural GBM share a common regulatory network. Supplementary Figure 4: *PTEN/p53 tumors rapidly progress and acquire the histological features of GBM. Supplementary Figure 5: *Pten tumors acquire and express mutations in p53. Supplementary Figure 6: *p53 tumors develop the histological features of GBM, and have an intermediate survival between *PTEN and *PTEN/p53 tumors.
Supplementary Table 3 from Invasive Lobular Carcinoma Cell Lines Are Characterized by Unique Estrogen-Mediated Gene Expression Patterns and Altered Tamoxifen Response
Authors: Sikora Matthew J. , Cooper Kristine L. , Bahreini Amir , Luthra Soumya , Wang Guoying , Chandran Uma R. , Davidson Nancy E. , Dabbs David J. , Welm Alana L. , Oesterreich Steffi
Published: April 2023

XLSX file - 17K, Expression data from estrogen deprivation studies using PDX HCI-013.
Supplementary Figure Legend from Activation of the FGFR–STAT3 Pathway in Breast Cancer Cells Induces a Hyaluronan-Rich Microenvironment That Licenses Tumor Formation
Authors: Bohrer Laura R. , Chuntova Pavlina , Bade Lindsey K. , Beadnell Thomas C. , Leon Ronald P. , Brady Nicholas J. , Ryu Yungil , Goldberg Jodi E. , Schmechel Stephen C. , Koopmeiners Joseph S. , McCarthy James B. , Schwertfeger Kathryn L.
Published: April 2023

PDF file - 45K
Supplementary Figure 3 from Activation of the FGFR–STAT3 Pathway in Breast Cancer Cells Induces a Hyaluronan-Rich Microenvironment That Licenses Tumor Formation
Authors: Bohrer Laura R. , Chuntova Pavlina , Bade Lindsey K. , Beadnell Thomas C. , Leon Ronald P. , Brady Nicholas J. , Ryu Yungil , Goldberg Jodi E. , Schmechel Stephen C. , Koopmeiners Joseph S. , McCarthy James B. , Schwertfeger Kathryn L.
Published: April 2023

PDF file - 45K, Supplemental Figure 3. HC-11 or HC-11/R1 cells were injected into the mammary fat pads of Balb/c mice. Mice were palpated to determine the % tumor free.
Supplementary Methods, Figure Legends from Mechanistic Elucidation of the Antitumor Properties of Withaferin A in Breast Cancer
Authors: Nagalingam Arumugam , Kuppusamy Panjamurthy , Singh Shivendra V. , Sharma Dipali , Saxena Neeraj K.
Published: April 2023

PDF file - 143KB
Supplementary Figure 2 from Expression of Variant Isoforms of the Tyrosine Kinase SYK Determines the Prognosis of Hepatocellular Carcinoma
Authors: Hong Jian , Yuan Yunfei , Wang Jianping , Liao Yadi , Zou Ruhai , Zhu Chuanlong , Li Binkui , Liang Yi , Huang Pinzhu , Wang Zongwei , Lin Wenyu , Zeng Yixin , Le Dai Jia , Chung Raymond T.
Published: April 2023

PDF file - 154KB, Supplementary Figure 2. Differential subcellular distribution of SYK(L) and SYK(S) in HCC.
Supplementary Figure 4 from Mechanistic Elucidation of the Antitumor Properties of Withaferin A in Breast Cancer
Authors: Nagalingam Arumugam , Kuppusamy Panjamurthy , Singh Shivendra V. , Sharma Dipali , Saxena Neeraj K.
Published: April 2023

PDF file - 147KB, Supplemental Figure 4 WFA activates RSK in an ERK-dependent manner.
Supplementary Figure 2 from Mechanistic Elucidation of the Antitumor Properties of Withaferin A in Breast Cancer
Authors: Nagalingam Arumugam , Kuppusamy Panjamurthy , Singh Shivendra V. , Sharma Dipali , Saxena Neeraj K.
Published: April 2023

PDF file - 89KB, Supplemental Figure 2 Withaferin A treatment inhibits expression of anti-apoptotic proteins, Survivin and XIAP and increases PARP cleavage.
Supplementary Figures 1 - 7, Tables 1 - 3 from Fatty Acid-Binding Protein E-FABP Restricts Tumor Growth by Promoting IFN-β Responses in Tumor-Associated Macrophages
Authors: Zhang Yuwen , Sun Yanwen , Rao Enyu , Yan Fei , Li Qiang , Zhang Ying , Silverstein Kevin A.T. , Liu Shujun , Sauter Edward , Cleary Margot P. , Li Bing
Published: April 2023

PDF file - 1745K, Supplementary Figure 1. The development of tumors in WT and E-FABP-/- mice. Supplementary Figure 2. Phenotype analysis of tumor-bearing WT and E-FABP-/- mice. Supplementary Figure 3. Dynamic changes of E-FABP-expressing TAMs in the tumor stroma. Supplementary Figure 4. Analysis of GM-BMMs from WT and E-FABP-/- mice. Supplementary Figure 5. Analysis of FABP expression and LD inhibition in GM-BMMs. Supplementary Figure 6. IFNγ production in tumor infiltrated cells and NK depletion in mice. Supplementary Figure 7. E-FABP expression in breast cancer patients. Supplementary Table 1. The selected differentially expressed genes in macrophages regulated by E-FABP. Supplementary Table 2. E-FABP expression in normal breast tissues and breast cancer tissues. Supplementary Table 3. E-FABP expression in normal breast stroma and invasive breast cancer stroma.
Supplementary Methods from VEGF Regulates Region-Specific Localization of Perivascular Bone Marrow–Derived Cells in Glioblastoma
Authors: Burrell Kelly , Singh Sanjay , Jalali Shahrzad , Hill Richard P. , Zadeh Gelareh
Published: April 2023

PDF file - 173KB
Supplementary Materials and Methods, Tables 1 - 3 from Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392
Authors: De Bellis Floriana , Carafa Vincenzo , Conte Mariarosaria , Rotili Dante , Petraglia Francesca , Matarese Filomena , Françoijs Kees-Jan , Ablain Julien , Valente Sergio , Castellano Rèmy , Goubard Armelle , Collette Yves , Mandoli Amit , Martens Joost H.A. , de Thé Hugues , Nebbioso Angela , Mai Antonello , Stunnenberg Hendrik G. , Altucci Lucia
Published: April 2023

PDF file - 160KB, Supplemental Materials and Methods. Supplemental Table 1. Primers. Supplemental Table 2. Analysis of the transcription level of the 148 genes associated with apoptosis revealed main differences between ATRA and MC2392. Supplemental Table 3. Primers used. Supplemental Table 4. Primers used in qPCR ChIP.
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Supplementary Figure S1. PDGF promotes tumorsphere formation in GICs through ID4-driven activation of Notch1signaling.
Supplementary Figure 3 from Context-Selective Death of Acute Myeloid Leukemia Cells Triggered by the Novel Hybrid Retinoid-HDAC Inhibitor MC2392
Authors: De Bellis Floriana , Carafa Vincenzo , Conte Mariarosaria , Rotili Dante , Petraglia Francesca , Matarese Filomena , Françoijs Kees-Jan , Ablain Julien , Valente Sergio , Castellano Rèmy , Goubard Armelle , Collette Yves , Mandoli Amit , Martens Joost H.A. , de Thé Hugues , Nebbioso Angela , Mai Antonello , Stunnenberg Hendrik G. , Altucci Lucia
Published: April 2023

PDF file - 37KB, ChIP analysis for MC2392 specific target genes.
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Supplementary Figure S6. No significant correlation of ID4 mRNA levels with NOS 1 or NOS3 mRNAs.
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Supplementary Figure S7. PDGF-NOS-ID4-miR-129 axis-relevant gene expression in tumor tissues derived from patients with GBM.
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Supplementary Figure S8. Expression of ID4, JAGGED1, NICD, PDGFB, PDGFRa, and NOS2 in PDGF-B-driven mouse gliomas.
Data Supplement from Mitochondrial Retrograde Signaling Mediated by UCP2 Inhibits Cancer Cell Proliferation and Tumorigenesis
Authors: Esteves Pauline , Pecqueur Claire , Ransy Céline , Esnous Catherine , Lenoir Véronique , Bouillaud Frédéric , Bulteau Anne-Laure , Lombès Anne , Prip-Buus Carina , Ricquier Daniel , Alves-Guerra Marie-Clotilde
Published: April 2023

Figure S2. Oxidative stress remains unaffected by UCP2 overexpression.
Data Supplement from Mitochondrial Retrograde Signaling Mediated by UCP2 Inhibits Cancer Cell Proliferation and Tumorigenesis
Authors: Esteves Pauline , Pecqueur Claire , Ransy Céline , Esnous Catherine , Lenoir Véronique , Bouillaud Frédéric , Bulteau Anne-Laure , Lombès Anne , Prip-Buus Carina , Ricquier Daniel , Alves-Guerra Marie-Clotilde
Published: April 2023

Figure S3. HK2 and PDK1 mRNA levels are down-regulated by UCP2.
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Legend for Supplementary Figures S1-S8.
Supplemental Figure S1 from Cytokine-like Molecule CCDC134 Contributes to CD8+ T-cell Effector Functions in Cancer Immunotherapy
Authors: Huang Jing , Xiao Lin , Gong Xiaoting , Shao Wenwei , Yin Yanhui , Liao Qinyuan , Meng Yang , Zhang Yingmei , Ma Dalong , Qiu Xiaoyan
Published: April 2023

Homo sapiens and Mus musculus CCDC134 are highly similar.
Supplementary Video 1 from Axon Guidance Factor SLIT2 Inhibits Neural Invasion and Metastasis in Pancreatic Cancer
Authors: Göhrig Andreas , Detjen Katharina M. , Hilfenhaus Georg , Körner Jan L. , Welzel Martina , Arsenic Ruza , Schmuck Rosa , Bahra Marcus , Wu Jane Y. , Wiedenmann Bertram , Fischer Christian
Published: April 2023

AVI file - 2196KB, Recording of unidirectional migration of MiaPaCa cells along a contacted neurite from a DRG-tumor cell co-culture assay (Example 1).
Supplementary Figure Legend from Cancer-Derived Mutations in KEAP1 Impair NRF2 Degradation but not Ubiquitination
Authors: Hast Bridgid E. , Cloer Erica W. , Goldfarb Dennis , Li Heng , Siesser Priscila F. , Yan Feng , Walter Vonn , Zheng Ning , Hayes D. Neil , Major Michael B.
Published: April 2023

PDF file - 72K
Supplementary Figure S4 from USP9X Downregulation Renders Breast Cancer Cells Resistant to Tamoxifen
Authors: Oosterkamp Hendrika M. , Hijmans E. Marielle , Brummelkamp Thijn R. , Canisius Sander , Wessels Lodewyk F.A. , Zwart Wilbert , Bernards René
Published: April 2023

Figure S4. Ingenuity Pathway enrichment and GO analysis of 1874 shUSP9X-affected genes not associated with estrogen induction. (A) Top canonical pathways (B) GO analyses for top enriched functions (top) and processes (bottom). FDR and p values are indicated.
Supplementary Figures 1 - 4 from PD-1 and Tim-3 Regulate the Expansion of Tumor Antigen–Specific CD8+ T Cells Induced by Melanoma Vaccines
Authors: Fourcade Julien , Sun Zhaojun , Pagliano Ornella , Chauvin Joe-Marc , Sander Cindy , Janjic Bratislav , Tarhini Ahmad A. , Tawbi Hussein A. , Kirkwood John M. , Moschos Stergios , Wang Hong , Guillaume Philippe , Luescher Immanuel F. , Krieg Arthur , Anderson Ana C. , Kuchroo Vijay K. , Zarour Hassane M.
Published: April 2023

PDF file - 292K, Supplementary Figure S1. Phenotype of vaccine-induced NY-ESO-1-specific CD4+ T cells. Supplementary Figure S2. Cytokine production, cytotoxic potential and cytolytic capacities of NY-ESO-1-specific CD8+ T cells following immunization in patients with spontaneous TA-specific CD8+ T cell responses before vaccination. Supplementary Figure S3. PD-1 and Tim-3 blockades increase the proliferation of vaccine-inducedNY-ESO-1-specific CD8+ T cells. Supplementary Figure S4. PD-1 and Tim-3 blockades increase the expansion of vaccine-induced cytokine-producing NY-ESO-1-specific CD8+ T cells.
Supplementary Figure 1 from Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells
Authors: Satelli Arun , Mitra Abhisek , Cutrera Jeffry J. , Devarie Marcos , Xia Xueqing , Ingram Davis R. , Dibra Denada , Somaiah Neeta , Torres Keila E. , Ravi Vinod , Ludwig Joseph A. , Kleinerman Eugenie S. , Li Shulin
Published: April 2023

PDF file - 3630KB, Detection of cell surface vimentin using western blotting, flow cytometry. Determination of specificity and sensitivity of 84-1 antibody.
Supplementary Figure 4 from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer
Authors: Thadani-Mulero Maria , Portella Luigi , Sun Shihua , Sung Matthew , Matov Alexandre , Vessella Robert L. , Corey Eva , Nanus David M. , Plymate Stephen R. , Giannakakou Paraskevi
Published: April 2023

PDF file - 176KB, LuCap 86.2 and LuCap 23.12 human prostate cancer xenografts treated with docetaxel 5 mg/kg weekly i.p or 20 mg/kg weekly i.p.
Supplementary Materials and Methods from NUP98 Fusion Oncoproteins Promote Aneuploidy by Attenuating the Mitotic Spindle Checkpoint
Authors: Salsi Valentina , Ferrari Silvia , Gorello Paolo , Fantini Sebastian , Chiavolelli Francesca , Mecucci Cristina , Zappavigna Vincenzo
Published: April 2023

PDF - 27K, Supplementary Materials and Methods.
Supplementary Movie 1 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: April 2023

MP4 file - 1431K, Supplementary movie S1: time-lapse video-microscopy with a 10x magnification objective, of Mel501 cells plated on plastic 48 hr after MOCK transfection.
Supplementary Figure 9 from β-Catenin Inhibitor ICAT Modulates the Invasive Motility of Melanoma Cells
Authors: Domingues Mélanie J. , Rambow Florian , Job Bastien , Papon Laura , Liu Wanguo , Larue Lionel , Bonaventure Jacky
Published: April 2023

PDF file - 218K, Un-cropped immunoblot images. Original images used to generate panels in Figures 6, 7, S3 and S5.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure 1:Three dimensional model of heparanase and over-expression of heparanase and the heparanase C-terminal domain (8C) in MCF10A cells.
Supplementary Figure 7 from ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor–Dependent HIF2α/VEGF Signaling Pathway
Authors: He Dalin , Li Lei , Zhu Guodong , Liang Liang , Guan Zhenfeng , Chang Luke , Chen Yuan , Yeh Shuyuan , Chang Chawnshang
Published: April 2023

PDF file - 3303K, Figure. S7. blocking AR signaling could inhibit AR positive cell migration, invasion and proliferation in a concentration-dependent in vivo and in vitro.
Supplemental Figures S1-S12 from CCR5 Receptor Antagonists Block Metastasis to Bone of v-Src Oncogene–Transformed Metastatic Prostate Cancer Cell Lines
Authors: Sicoli Daniela , Jiao Xuanmao , Ju Xiaoming , Velasco-Velazquez Marco , Ertel Adam , Addya Sankar , Li Zhiping , Andò Sebastiano , Fatatis Alessandro , Paudyal Bishnuhari , Cristofanilli Massimo , Thakur Mathew L. , Lisanti Michael P. , Pestell Richard G.
Published: April 2023

Supplemental Figures S1-S12. Supplement 1. High resolution images of normal prostate and v-Src-PEC tumor Supplement 2. AR, CK5 and CK8 abundances in cultured v-Src-PECs compared with primary cultured normal PECs detected by western-blot. Supplement 3. High resolution images of v-Src-PEC bone metastasis tumor and adjacent bone marrow Supplement 4. Kegg-pathway analysis of up-regulated genes in v-Src-PEC tumor vs normal prostate Supplement 5. High resolution gene expression profile comparing normal FVB murine prostate epithelial cells Supplement 6. Validation of CCR5 expression by qtPCR in v-Src-PEC tumors derived by subcutaneous injection compared with normal prostate Supplement 7. CCR5 expression in public available database Supplement 8. FACS analysis of CCR5 positive population in v-Src-PECs Supplement 9. High resolution image of immunohistochemical staining for CCR5 in v-Src-PEC metastasis in bone which showed in figure 5 Supplement 10. High resolution image of (A-D) histological images Supplement 11. CK5 (A) and CK8 (C) immunohistochemical staining in the prostate of castrated mice vs normal mice. Supplement 12. CCR5 IHC staining in bone metastasis v-Src-PEC tumor.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: April 2023

Supplementary Figure S3. Body weight changes in xenograft model in athymic nude mice with time, and a concentration-dependent increase in DNMTs activity under treatment with afatinib.
Data Supplement from Afatinib Enhances the Efficacy of Conventional Chemotherapeutic Agents by Eradicating Cancer Stem–like Cells
Authors: Wang Xiao-kun , He Jie-hua , Xu Jing-hong , Ye Sheng , Wang Fang , Zhang Hui , Huang Zhen-cong , To Kenneth Kin Wah , Fu Li-wu
Published: April 2023

Supplementary methods
Supplementary Figure S3 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: April 2023

Supplemental Figure S3: Immunohistochemical staining of tumors using cmHsp70.1 monoclonal antibody
Supplementary Figure S2 from Selective In Vivo Imaging of Syngeneic, Spontaneous, and Xenograft Tumors Using a Novel Tumor Cell–Specific Hsp70 Peptide-Based Probe
Authors: Stangl Stefan , Varga Julia , Freysoldt Bianca , Trajkovic-Arsic Marija , Siveke Jens T. , Greten Florian R. , Ntziachristos Vasilis , Multhoff Gabriele
Published: April 2023

Supplemental Figures S2A,B: Discrimination of TPP[Cy5.5] and CP[DL750] fluorescence using NIRF imaging system. Figure S2A: unspecific excitation of CP[DL750] and TPP[Cy5.5]. Figure S2B: Tumor to background ratio (TBR) of primary lesions and lung metastases using control peptides CP[DL750] and CP[Cy5.5]
Supplementary Figure 2 from RAGE Expression in Tumor-Associated Macrophages Promotes Angiogenesis in Glioma
Authors: Chen Xuebo , Zhang Leying , Zhang Ian Y. , Liang Junling , Wang Huaqing , Ouyang Mao , Wu Shihua , da Fonseca Anna Carolina Carvalho , Weng Lihong , Yamamoto Yasuhiko , Yamamoto Hiroshi , Natarajan Rama , Badie Behnam
Published: April 2023

Supplementary Fig. 2: RAGE ablation in GL261 gliomas results in the formation of dilated, leaky vessels.
Supplementary Table 2 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 96K, Clinicopathologic characteristics of miR-22 expression in breast cancer patients.
Supplementary Figure 1 from RAGE Expression in Tumor-Associated Macrophages Promotes Angiogenesis in Glioma
Authors: Chen Xuebo , Zhang Leying , Zhang Ian Y. , Liang Junling , Wang Huaqing , Ouyang Mao , Wu Shihua , da Fonseca Anna Carolina Carvalho , Weng Lihong , Yamamoto Yasuhiko , Yamamoto Hiroshi , Natarajan Rama , Badie Behnam
Published: April 2023

Supplementary Fig. 1: Expression of RAGE in the GL261 glioma blood vessels (CD31+).
Supplementary Figure 6 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 44K, The expression of miR-22 in breast cancer tissues.
Supplementary Table 3 from The Cancer Stem Cell Marker Aldehyde Dehydrogenase Is Required to Maintain a Drug-Tolerant Tumor Cell Subpopulation
Authors: Raha Debasish , Wilson Timothy R. , Peng Jing , Peterson David , Yue Peng , Evangelista Marie , Wilson Catherine , Merchant Mark , Settleman Jeff
Published: April 2023

XLSX file - 41KB, IC50 values for kinase inhibitors used in the study.
Supplementary Figure 2 from A Regulatory Loop Involving miR-22, Sp1, and c-Myc Modulates CD147 Expression in Breast Cancer Invasion and Metastasis
Authors: Kong Ling-Min , Liao Cheng-Gong , Zhang Yang , Xu Jing , Li Yu , Huang Wan , Zhang Yi , Bian Huijie , Chen Zhi-Nan
Published: April 2023

PDF file - 37K, Luciferase assays the effect of Sp3 and Sp4 on CD147 transcription regulation.