bluuebunny/crossref_metadata_2025 huggingface dataset:
Utilizing Technology to Improve the Quality of Learning in Indonesia: Challenges and Consequences for Arabic Teachers
Authors: Ritonga Mahyudin , Sobhan Sobhan , Bambang Bambang , Khadidja Safi
Published: September 2022

Islamic boarding schools are identical to traditional learning because they ignore and do not respond to technological developments. This study aims to describe the media used in Islamic boarding schools in teaching Arabic, teachers' perceptions of technology-based media, and opportunities to change the media used in Arabic learning in Islamic boarding schools. This study was conducted with a qualitative approach in Islamic boarding schools where students were selected according to their needs. Data were collected by observation, interviews, and documentation studies. Based on the results, the Batang Kabung Islamic Boarding School used traditional learning media. However, there are open opportunities to apply technology-based media because of the openness of pesantren in accepting changes with an internet connection, human resources for education staff, and students' ability to operate technology-based learning media. The consequences faced by Islamic boarding schools are curriculum revisions, more operational costs, adjustment of methods with learning media, and the need to improve teacher competencies in utilizing technology-based media.
Teaching Aids Development for Arabic Lessons to Enhance Student’s Reading Skills
Authors: Zarkasyi Ahmad Hidayatullah , Hanina Gita , Fauziah Siti Anne Barkah Nur
Published: September 2022

This study aims to enhance students reading skills of the ninth-grade students in Madrasah I'dadiyah Muhammadiyah. This research is research and development Borg & Gall study used to obtain a specific production, know the effectiveness of its implementation, and verify its validity for scholars, using the qualitative and quantitative approach to analyze quantitative and qualitative data. The methods used in it consisted of interviews, Tests, questionnaires, and written documents. In analyzing the data, this research used the Statistical Package for the Social Sciences, version 25 SPSS 25 method T-Test, and the Wilcoxon Signed. The developed educational aids come in the Android program by choosing the appropriate material, exercises, and teaching methods. The effectiveness is obtained from the results of the pre and post-tests by implementing: descriptive statistical analysis, conditional testing, and inferential testing in the extended experiment, and the result indicates that there is progress in their language proficiency, especially in reading skills. These teaching aids are attractive and exciting and help students learn Arabic, especially reading Arabic.
Evidence of Type A-Like Killer Whales (Orcinus orca) Predating on Marine Mammals Along the Atacama Desert Coast, Chile
Authors: García-Cegarra Ana M.
Published: September 2022

Killer whales (Orcinus orca) are marine apex predators distributed across the world’s oceans. In the last 40 years, researchers have increasingly differentiated killer whales into ecotypes based on genetics, morphology, behaviour, acoustic repertoire, habitat, and trophic ecology. While killer whale ecotypes in the Northern Hemisphere are well studied, the recognition of distinct killer whale forms in the Southern Hemisphere is mainly limited to Antarctic waters. Although present in less studied regions, such as along the Atacama Desert coast in the Southeast Pacific Ocean, limited information is available regarding their biology or trophic ecology. Herein, multiple lines of evidence are presented for killer whale predation on marine mammals in northern Chile. Using information from systematic boat-based surveys, whale-watching tour surveys, and reports from fishermen/citizen scientists, 19 killer whale sightings are reported along the coast of northern Chile (from the Arica and Parinacota region in the north to the Atacama region in the south). Killer whales were photo-identified as corresponding to the Southern Hemisphere Type A-like ecotype according to their dorsal fin shape and white eye patch. One killer whale pod, which included two males, one female, one juvenile, and one calf, was resighted six times from 2016 to 2021 in northern Chile and was observed hunting South American sea lions (Otaria flavescens), dusky dolphins (Lagenorhynchus obscurus), and long-beaked common dolphins (Delphinus cf. capensis). Killer whales were observed taking advantage of large aggregations of sea lions associated with the offshore purse-seine fishery. Adult killer whales used the hulls of fishing vessels to prevent sea lions from escaping. Photo-identification analysis of a fin whale (Balaenoptera physalus) catalogue from Mejillones Peninsula showed that 2.6% of all identified whales had apparent rake marks from killer whale teeth on their dorsal fins. These data show that Type A-like killer whales in northern Chile prey on several species of marine mammals.
İlkokul 3. Sınıf Öğrencilerinin Doğal Sayılar Konusundaki Kavram Yanılgıları ve Hata Türlerinin İncelenmesi
Authors: DOĞAN Adem , AKYAR Kerime
Published: September 2022

Toplama, çıkarma, çarpma ve bölme konusu okul öncesi dönemden başlayıp bunu takip eden diğer öğretim kademelerinde de devam etmektedir. Doğal sayılar konusundaki işlemlerin öğrencilerin tarafından iyi anlaşılması olası hataların önüne geçmektedir. Genel olarak öğrencilerin iyi öğrenemediği kavramlarda hatalar görülmektedir. Kavram yanılgısı, kişinin bir bilgiyi doğru olarak kabul edip birçok durumda bu yanlış bilgiyi kaynak olarak kullanarak yanlış kavramlara ya da genellemelere ulaşmasıdır. Kavram yanılgılarının en temel özelliği ise rastlantısal olarak gerçekleşen hatalardan farklı olarak genel yanlış bir bilginin kişinin zihninde yer etmesidir. Çalışmanın amacı ilkokul 3. sınıf öğrencilerinin doğal sayılar konusundaki kavram yanılgıları ve hata türlerinin incelenip hataların nedenlerine göre sınıflandırılmasıdır. Çalışma temel nitel araştırma modeli olarak yürütülmüştür. Çalışma grubunu 2020-2021 eğitim öğretim yılında, Güneydoğu Anadolu Bölgesi’nde bulunan bir ilin merkez ilçesinde, ilkokul 3. sınıfta öğrenim gören 100 öğrenci oluşturmaktadır. Çalışma grubu amaçlı örnekleme yoluyla seçilmiştir. Veri toplama aracı olarak araştırmacılar tarafından hazırlanan ve 20 sorudan oluşan ‘‘3. Sınıf Doğal Sayı Soruları’’ testi kullanılmıştır. Verilerin analizinde doküman analizinden yararlanılmıştır. Ölçme aracına verilen cevaplar betimsel analize tabii tutularak değerlendirilmiştir. Araştırma sonucunda öğrencilerin en fazla sayıların karşılaştırılması ve bölme işleminde hata yaptığı görülmüştür. Öğrencilerin yaptığı temel hataların sayma hatası, verilen temsillerin ifade ettiği sayıyı yazamama ve verilmeyen çıkanı bulma konuları olduğu; yapılan en az hataların ise sembol hatası, işlem yönünü karıştırma, onluk bozamama ve sonucu 0, 1 ve 9 olarak yazma, birler basamağı ile birler basamağını, onlar basamağı ile onlar basamağını çarpıp işlemi tek satırda bitirme olarak görülmüştür. İlkokul 3. sınıf öğrencilerinin yaptıkları hataların nedenleri; (i) pedagojik hata, (ii) epistemolojik hata, (iii) psikolojik hata olarak değerlendirilmiştir. Öğrencilerin yaptığı hataların nedenlerine bakıldığında epistemolojik hatanın daha fazla olduğu sonucuna varılmıştır.
Temettü Veriminin BIST Hisse Senedi Fiyatlarını Tahmin Gücünün Nedensellik Testleriyle Analizi
Authors: CAMGÖZ Mevlüt
Published: September 2022

Bu çalışmada Campbell ve Shiller (1988a) modelinden hareketle, temettü veriminin BIST hisse senedi fiyatlarını tahmin gücü incelenmektedir. Araştırmada, temettü veriminin hisse senedi fiyatlarını tahmin etmede başarılı bir faktör olup olmadığı test edilecektir. Çalışma, teorisyenler, yatırımcılar ve politika yapıcılar açısından önemli çıkarımlara sahiptir. Öncelikle, kâr payı ödemelerinin firma değerine etkisinin ortaya koyulmuş olması, yöneticiler açısından temettü dağıtım politikalarının oluşturulmasında belirleyici olacaktır. Ayrıca, temettü veriminin tahmin gücünün ortaya koyulması durumunda, yatırımcılar ve portföy yöneticileri, bugünkü değer (present value) yaklaşımını kullanarak belirli bir hisse senedinin yüksek veya düşük değerlenmiş olduğunu tespit edebilirler. Temettü ödemelerinin piyasa dinamiklerine olan etkilerinin bilinmesi, düzenleyici otoritelerin politika kararlarında da yol gösterici olacaktır. Araştırma metodolojisi olarak Toda-Yamamoto (1995) ve Hatemi-J (2012) asimetrik bootstrap nedensellik testleri benimsenmiştir. Araştırmada, Aralık 2011–Kasım 2021 tarihlerinde BIST 100 endeksinde devamlılık gösteren ve kesintisiz olarak temettü ödeyen hisse senetlerine ait temettü verimi ve ay sonu kapanış fiyatı serileri kullanılmıştır. Toda-Yamamoto nedensellik testi bulgularına göre AGHOL, BIMAS, EGEEN, INDES, SARKY, SELEC ve TOASO hisse senetlerinde temettü veriminden hisse senedi fiyatlarına doğru nedensellik ilişkisi tespit edilmiştir. Hatemi-J (2012) asimetrik bootstrap nedensellik testi, Toda-Yamamoto testine nazaran daha az sayıda nedensellik ilişkisine işaret etmektedir. İncelenen çoğu hisse senedinde temettü verimi ve fiyat değişkenlerinin pozitif ya da negatif bileşenleri arasında nedensellik ilişkisi saptanmamıştır. Temettü veriminin tahmin gücüyle ilgili karışık bulgulara ulaşılmasının arka planında, incelenen değişkenlerde yapısal kırılmaların görülmesi, temettü veriminin tahmin gücünün zamanla değişen bir yapıda olması, piyasa şartlarına bağlı olarak tahmin gücünün zayıflaması, temettü verimi ve fiyat arasındaki ilişkinin nonlineer yapıda gerçekleşebilmesi, hisse senedi bazında yapılan sınamaların endeks bazında yapılan sınamalara nazaran dezavantajlı olması, aylık frekanstaki gözlemlerden ziyade yıllık frekanstaki gözlemlerin kullanılması durumunda, temettü veriminin tahmin gücünün daha fazla artış gösteriyor olması, firmaların temettü politikasındaki değişikliklerin ve hisse geri alım kararlarının temettü veriminin tahmin gücünü zayıflatıyor olması sayılabilir.
Identification and bioinformatic analysis of invA gene of Salmonella in free range chicken
Authors: Mohammed B. T.
Published: September 2022

Abstract Salmonella is a serious cause of the health issues in human and animal worldwide. Salmonella has been isolated from different biological samples and it considers as the key role in induction of inflammation of gastrointestinal tract which in turn cause diarrhoea in different species. To further understand the involvement of Salmonella in contaminating and infecting fresh eggs and meat of free-range chicken. This study aimed to establish the microbiological and molecular detections of Salmonella in the cloaca of the free-range chicken and to identify predicted biological functions using Kyoto Encyclopedia of Gene and Genomic (KEGG) pathways and protein-protein interaction. Cloacal swabs were collected from free range chicken raised in the local farm in Duhok city. The isolates were cultured and biochemical test performed using XLD and TSI, respectively. Molecular detection and functional annotation of invA gene was carried out using Conventional PCR and bioinformatics approaches. The present study found that Salmonella was detected in 36 out of 86 samples using microbiological methods. To confirm these findings, invA gene was utilised and 9 out of 36 Salmonella isolates have shown a positive signal of invA by agarose gel. In addition, bioinformatic analysis revealed that invA gene was mainly associated with bacterial secretion processes as well as their KEGG terms and Protein-Protein Interaction were involved in bacterial invasion and secretion pathways. These findings suggested that invA gene plays important role in regulating colonization and invasion processes of Salmonella within the gut host in the free range chicken.
Dietary patterns and cardiometabolic risk factors of a federal public institution staff in the northern region of Brazil
Authors: LOPES Elisama Costa , REZENDE Fabiane Aparecida Canaan , PEREIRA Renata Junqueira
Published: September 2022

ABSTRACT Objective To identify dietary patterns in an adult population and assess those patterns association with cardiometabolic risk factors. Methods Cross-sectional study conducted with 130 workers of a university in Tocantins, Brazil, aged 20-59 years. Dietary patterns were identified by principal component analysis based on a food frequency questionnaire. Body mass index, waist circumference, blood pressure, fasting glycemia, triacylglycerols, low-density lipoprotein and high-density lipoprotein cholesterol were measured. Multinomial logistic regression was used to assess the association between dietary patterns and cardiometabolic risk factors. Results Three dietary patterns were identified that together explained 78.74% of total variance: healthy, western and fit dietary patterns. In the adjusted model, greater adherence to the healthy pattern was associated with lower fasting glucose values (OR: 0.89; 95%IC: 0.82-0.97; p=0.009) and with higher concentrations of low-density lipoprotein cholesterol (OR: 1.02; 95%IC: 1.00-1.04; p=0.024); the western dietary pattern was associated with higher fasting glucose values (OR: 1.06; 95%IC: 1.00-1.13; p=0.05) and the fit pattern was associated with lower concentrations of low-density lipoprotein cholesterol (OR: 0.98; 95%IC: 0.97-0.99; p=0.048). Conclusion Food was an important risk and protective factor for cardiometabolic changes.
The CEO’s origin and fame in relation to company performance and market perception
Authors: Marcolino Lucas Tresso Caruso , Silva Vinicius Augusto Brunassi
Published: September 2022

Abstract This article investigated decisions to change chief executive officer (CEO) and the relationships between the characteristics of the new CEO chosen and both company performance and stock market perceptions. Our study aims to broaden the understanding in an area that remains underexplored by the literature. In particular, we present a new direction for the study of Malmendier and Tate (2009) by addressing the question of superstar CEOs considering the market’s perception regarding the hiring of an executive and their performance in the new company. The article highlights a new research question that permeates the market’s perception with regard to changing executives classified as superstars. In addition, the study connects the literature on superstar CEOs and changing executives, presenting new findings for the theme. The results obtained provide new findings for the literature and elucidate that superstar CEOs are positively evaluated by the market at the time of the hiring announcement. However, these executives do not show better performance than the other companies in the sector in subsequent periods, which corroborates and extends the negative aspects found by Malmendier and Tate (2009). The methodology used was an event study, OLS, Logit, and Probit. This article highlights that bigger companies with better operational performance have a greater probability of choosing a new CEO with superstar status in situations of changing executives. CEOs of external origin and classified as superstars are, on average, better evaluated than their peers by the market in the event window relating to the hiring announcement. However, the performance of these executives may fall short of the results calculated for the sector average. The aforementioned results broaden the discussion regarding decisions to change executives and highlight new findings about the role of the CEO’s origin and their status of recognition and fame.
Insecticidal activity of Piper aduncum oil: variation in dillapiole content and chemical and toxicological stability during storage
Authors: FAZOLIN Murilo , MONTEIRO André Fabio Medeiros , BIZZO Humberto Ribeiro , GAMA Paola Ervatti , VIANA Luana de Oliveira , LIMA Maria Érica Costa de
Published: September 2022

ABSTRACT The insecticidal effect of the essential oil of Piper aduncum (EOPA), and of its constituent dillapiole [1-allyl-2,3-dimethoxy-4,5-(methylenedioxy) benzene] in particular, is well documented in the literature and can be associated with its interference with the enzymatic detoxification in arthropods. However, no data exist on the range of dillapiole content associated with insecticidal activity, which is necessary to establish reliable dose-activity parameters for a formulated product. The oil composition can also change during storage after distillation, mainly due to environmental factors such as light incidence, atmospheric oxygen and temperature, which can be deleterious to oil quality. In this study, EOPA subjected to different storage conditions over four years and its rectified fractions were submitted to bioassays to evaluate their insecticidal effect by topical contact and residual contact against Spodoptera frugiperda. Our objectives were to determine the relationship between dillapiole content and the insecticidal activity of EOPA, and to evaluate its chemical and toxicological properties over time under different conditions. Our results showed that EOPA was stable with respect to the dillapiole content and the toxicological effect against S. frugiperda under different storage conditions for four years. The overall chemical composition of the EOPA did not vary significantly among storage conditions. EOPA with dillapiole content ranging between 68% and 100% showed greater insecticidal toxicity by residual and topical contact against S. frugiperda larvae.
A case study of an adolescent according to A Model of Children’s Adjustment to Parental Cancer
Authors: Sousa Ana Filipa Domingues , Santos Diana Gabriela Simões Marques , Costeira Cristina Raquel Baptista , Ferreira Maria Margarida da Silva Reis dos Santos , Lomba Maria de Lurdes Lopes de Freitas
Published: September 2022

ABSTRACT Objective: To describe and analyze the experience of an adolescent experiencing parental cancer, based on A Model of Children’s Adjustment to Parental Cancer, and to prescribe nursing interventions in classified language. Method: This is a single case study, qualitative, of a 16-year-old adolescent experiencing maternal cancer. We analyzed a semi-structured interview, based on a script conceptualized by the selected theoretical model. Data processing took place through content analysis. Authorization was obtained from the Research Ethics Committee TI 25/2020. Results: The analysis of the adolescent’s interview allowed identifying categories in agreement with the model variables. Psychosocial adjustment dimensions and stress response symptoms, such as academic performance and somatic symptoms, were recognized in the adolescent’s adjustment process. Nursing interventions will focus on education and support. Conclusion: The theoretical model contributed to assess the needs of adolescents experiencing parental cancer, allowing nursing interventions to be prescribed in classified language that consider moderating and mediating variables, promoting adjustment. The model proved to be suitable for future interventions for adolescents experiencing similar situations.
Characterization and expression of the gene glucose transporter 2 (GLUT2) in embryonic, larval and adult Bay snook Petenia splendida (Cichliformes: Cichlidae)
Authors: Castillo-Collado Alejandra del Carmen , Frías-Quintana Carlos Alfonso , Morales-Garcia Vicente , Alvarez-Villagomez Carina Shianya , Asencio-Alcudia Gloria , Peña-Marín Emyr Saul , Martínez-Bautista Gil , Jiménez-Martinez Luis Daniel , Álvarez-González Carlos Alfonso
Published: September 2022

Abstract Bay snook (Petenia splendida) is a carnivorous cichlid species with excellent economic value in Southeast Mexico. Although this species presents an excellent potential for commercial aquaculture, the information about its nutritional, physiological, and reproductive metabolic pathways is meager. The current study focuses on the expression of glucose transporter 2 (glut2) in embryos and larvae at 5, 10, 15-, 20-, 25-, and 30-days post-hatch (dph) and in the liver, intestine, kidney, muscle, heart, testicle, gill, stomach, pancreas, and brain of adult fish. The partial sequence of glut2 was obtained, and specific qPCR primers were designed. In embryos, the expression was lower compared to larvae at 5, 15, and 20 dph. The highest expression in larvae occurred at 20 dph and the lowest at 25 and 30 dph. Maximum expression levels in adults occurred in the liver and intestine. Our results show that glut2 is expressed differentially across tissues of adult bay snook, and it fluctuates during larval development.
Sobre uma Impossibilidade de Instauração de Dissensos: fragmentos para um pequeno dicionário de verbos da pedagogia do teatro
Authors: Gomes Sidmar Silveira
Published: September 2022

RESUMO Sobre uma Impossibilidade de Instauração de Dissensos: fragmentos para um pequeno dicionário de verbos da pedagogia do teatro – Inspirada no trato arquivístico de Michel Foucault, este artigo nasce da investigação em que se fez um mapeamento de artigos que versam sobre a pedagogia do teatro em 10 periódicos científicos da área das Artes e das Artes Cênicas. Deuse a ver no interior de tal arquivo empírico um conjunto de 21 verbos regulares, a conduzir as condutas aí implicadas. Organizou-se, então, uma espécie de dicionário da pedagogia do teatro, valendo-se da apresentação em série de trechos desses artigos nos quais esses verbos estão presentes. Tal tecitura revela a maquinaria de veridicção atinente ao campo da pedagogia do teatro, evidenciando uma tendência à impossibilidade da instauração de dissensos.
Research advances in vegetable-oil-based pressure-sensitive adhesives
Authors: Ma Yufeng , Ji Yuan , Zhang Jiale , Sha Ye , Jia Puyou , Zhou Yonghong
Published: September 2022

Pressure-sensitive adhesive (PSA) is a kind of viscoelastic material with the viscous properties of liquids and the elastic properties of solids that can adhere to the surfaces of various substrates only under light pressure without phase change. PSAs derived from petroleum-based materials are generally non-biodegradable and disposable; therefore, a large amount of waste is generated from PSA products. Preparation of PSAs using renewable vegetable oil as raw material is an effective way to reduce dependence on petrochemical resources and environmental pollution. This paper summarizes the recent progress on vegetable-oil-based PSAs. Vegetable-oil-based PSAs mainly include epoxy resin, acrylic resin, fatty acid derivatives, polyester and polyurethane according to the chemical structures of vegetable-oil-based polymers. The design ideas and modification methods of vegetable-oil-based PSAs are introduced, including the development of functional vegetable oil monomers and the optimization of the polymer structure, so as to provide theory and reference for the design and development of new bio-based PSAs.
Earthship buildings: opinions on their contribution towards sustainable alternative housing in the UK
Authors: Booth Colin A , Horry Rosemary , Isaac Cameron , Mahamadu Abdul-Majeed , Manu Patrick , Awuah Kwasi G B , Aboagye-Nimo Emmanuel , Georgakis Panagiotis , Prabhakaran Abhinesh
Published: September 2022

Earthship buildings are marketed as being an epitome of sustainable alternative housing. Built by reusing or repurposing mostly reclaimed urban waste products, their design includes the utilisation of low-embodied-energy materials, passive solar heating and cooling, photovoltaic power systems, rainwater harvesting and solar hot water heating, along with black- and greywater-treatment systems. This study explores stakeholder opinions of whether Earthship buildings can contribute towards the future of alternative housing in the UK. Opinions were sought through a questionnaire completed by UK members of online social media groups whose shared focus is related to sustainability (n = 50). The results reveal that the public believe that the main benefits are their minimal environmental impact and also their reliance on renewable energy resources, while the main barriers are identifying suitable building plots and obtaining the necessary planning permissions. Notwithstanding that the participants included in this study already have sustainability interests, it is surmised that the public deem that the general principles of Earthships are an acceptable choice of alternative home/living. However, while the uptake of Earthship homes proves increasingly popular in some parts of the world, the utmost concern within the UK setting is the reality of finding somewhere suitable to build an Earthship and acquiring necessary authorisations to construct the building.
Intervenciones de estilo de vida en pacientes con úlceras venosas y su asociación con la cicatrización: scoping review
Authors: Cifuentes-Rodríguez Johana Enyd , Guerrero-Gamboa Sandra
Published: September 2022

Objetivos: identificar y describir la evidencia disponible sobre intervenciones de estilo de vida diseñadas para promover la cicatrización y prevenir la recurrencia de úlceras venosas. Métodos: scoping review guiada por el marco metodológico de Arksey y O’Malley, de estudios de intervención publicados entre los años 2008-2020 en idioma inglés, español y portugués en las bases de datos PubMed, Cochrane Library y CINAHL, utilizando las palabras clave: venous leg ulcer, lifestyle intervention, nutritional support, exercise, wound healing, recurrence. Resultados: veinte estudios fueron incluidos en la síntesis. La mayoría de las intervenciones se enfocaron en promover el ejercicio y analizar sus efectos en la cicatrización de las úlceras venosas. Solo cuatro estudios de intervención abordaron el aspecto nutricional de estos pacientes y apenas tres determinaron la recurrencia. Los hallazgos son limitados debido a la diversidad en la concepción y ejecución de las intervenciones disponibles además de las muestras pequeñas en los estudios. Conclusiones: la evidencia existente sugiere que las intervenciones que promueven la actividad física y el ejercicio podrían tener un efecto beneficioso en la cicatrización y prevención de recurrencia de úlceras venosas, sin embargo, falta una base sólida de evidencia en intervenciones de estilo de vida para estos pacientes. La investigación actual proporciona algunas ideas sobre los componentes específicos que deben considerarse al planificar tales intervenciones en el futuro.
Situações de vulnerabilidades vivenciadas por adolescentes infratores: uma revisão integrativa
Authors: Santos-Couto Pablo Luiz , Teixeira-Santana Carla Dielle , Alves-Vilela Alba Benemérita , Tosoli-Gomes Antônio Marcos , Da Silva-Flores Tarcísio , Da Costa-Pereira Samantha Souza , Coelho-Gomes da Silva Sandra Célia , Costa-Ferreira Luana
Published: September 2022

Objetivo: analisar as situações de vulnerabilidade vivenciadas por adolescentes que praticam atos infracionais. Materiais e Métodos: trata-se de uma revisão integrativa de literatura, realizada nas bases de dados Scientific Eletronic Library Online (Scielo), Biblioteca Virtual em Saúde (BVS) e Medical Literature Analysis and Retrieval System Online (Medline), que resultou em 33 estudos incluídos, publicados entre os anos de 2009 a 2019, e, que após análise de conteúdo semântica, originou quatro categorias. Resultados: os resultados foram apresentados nas categorias: relações familiares conflituosas; envolvimento com álcool e drogas; situações sociodemográficas desfavoráveis; vulnerabilidade programática e a ausência do Estado. Conclusão: este estudo aponta como contribuição para a prática dos profissionais, sobretudo da atenção primária, estratégias para analisar as situações de vulnerabilidades que adolescentes infratores vivenciam, e assim, atuar na promoção da saúde, minimização dos agravos e auxílio para a reinserção social.
Crisis ecológica y determinación social de la salud y la vida
Authors: Sepúlveda Gallego Luz Elena
Published: September 2022

A partir de una caracterización general de la crisis ecológica que se vive en el planeta, se presenta la multidimensionalidad y complejidad de los conceptos de salud y determinación social de la salud y la Vida, para fundamentar la necesidad de imbricar los enfoques sociológico, económico, ético, político,  ecológico ambiental y biológico en la formación de los profesionales en salud que requiere Colombia en el siglo XXI.
Sistematización de una sistematización: aprendizajes sobre el método
Authors: Lopera Uribe Gloria Elena , Villa Vélez Lilliana , Castaño Pineda Yeferson , Betancurth Loaiza Diana Paola , Peñaranda Correa Fernando , Escobar Paucar Gloria Matilde , Bastidas Acevedo Miriam , Gómez Correa Jaime Arturo , Vásquez Velásquez Ana María , Bolívar Buriticá Wilson Antonio
Published: September 2022

Objetivo: presentar los aprendizajes de una sistematización como método, para la construcción de conocimiento basado en la experiencia vivida por los propios investigadores de varios proyectos sobre la educación en crianza, en el campo de la salud pública, llevado a cabo en la vereda Granizal, Antioquia, durante el período 2013-2019. Materiales y método: se empleó la sistematización de experiencias y los participantes fueron los mismos investigadores. Se inició con la organización de los materiales, los diarios de campo de los círculos de investigación temática y relatorías de las reuniones del equipo de investigación y de los actores comunitarios. Se siguió con la elaboración de una matriz con la recuperación histórica. Y, finalmente, de las reflexiones grupales, surgieron categorías y relaciones para la construcción teórica de visión de conjunto. Resultados: se presenta la propuesta teórica de la sistematización y los procedimientos para implementarla, orientada por cinco momentos: vivir la experiencia, formular un plan de sistematización, recuperar el proceso vivido, las reflexiones de fondo y los puntos de llegada. Se destacan cuatro rasgos de la sistematización: una investigación creativa; basada en un proceso de construcción colectiva; para aprender de la práctica y construir conocimiento; y como escenario transformador de esta y de quienes la realizaron. Conclusión: la “sistematización de la sistematización” permitió hacer conciencia sobre la propia praxis investigativa. Muestra la comprensión del grupo acerca de la conceptualización y metodología de esta perspectiva investigativa. Trasciende la recopilación y organización de la información del proceso vivido en la medida en que la reconstrucción de la experiencia es una comprensión más amplia que transforma la práctica de los sujetos involucrados.
Prácticas culturales de cuidado en el binomio madrehijo durante el puerperio: Revisión integrativa
Authors: Vargas Vásquez Alix Nathalya , Mantilla María Inés , Moncada Caicedo Ana María , Castro Yara Angie Paola
Published: September 2022

Objetivo: identificar en la literatura las prácticas culturales de cuidado postnatal que realizan las mujeres y su familia durante el puerperio. Metodología: se realizó una revisión integrativa a través de búsqueda en las bases de datos: Gale Cengage Learning, Scielo, Redalyc, Dialnet, EBSCO, Proquest, Science Direct, PubMed y Medigraphic en idiomas inglés, español y portugués entre 2014 y 2019, utilizando los términos: prácticas de cuidado cultural, cuidado en el puerperio, cuidado al recién nacido y cuidado de enfermería materno perinatal; los datos se analizaron a partir de la construcción de una matriz en Excel. Resultados: se obtuvieron 70 artículos, de los cuales emergieron cuatro categorías temáticas de prácticas de cuidado cultural: cuidado de la mujer consigo misma, cuidado del neonato por la madre/familia, cuidado institucional de la puérpera y del neonato, siendo la lactancia materna el factor común entre las ellas. Conclusiones: la identificación de diversas prácticas de cuidado postnatal en el ámbito hospitalario y ambulatorio varían por aspectos sociales, económicos y culturales, pero la mayoría de ellas favorecen el vínculo con el neonato. Es difícil establecer prácticas culturales generalizadas yestáticas en Colombia, debido a la diversidad cultural dentro de cada país.
Actitudes de los docentes de secundaria frente a la educación sexual de los adolescentes
Authors: Coime España Gisella , Vergara Jiménez Lina Marcela , Reyes Narváez María Fernanda , Quintero Mora Rubén Guillermo , Giraldo Osorio Rubiela
Published: September 2022

La educación sexual (ES) desde la escolaridad ha sido un tema de intereses con diversas variaciones ante posturas biologicistas, moralistas, preventivas, además de aquellas con un eje integrador y de derechos. La actitud de los educadores frente a la sexualidad representa un componente que puede influir en la enseñanza de la ES, por lo cual se planteó como objetivo: describir la evidencia científica respecto a las actitudes relacionadas con la educación sexual (ES) en docentes de instituciones educativas de secundaria. Materiales y métodos: se realizó una revisión sistemática exploratoria de la literatura científica publicada en el mundo, utilizando las palabras clave school teacher, sex education y attitude; en los idiomas inglés, portugués y español; de los años 2003 a 2019, mediante búsqueda en las bases de datos SciELO, Scopus, Cinhal, Ovid y BVSL y en artículos de referencias. Fueron evaluadas por dos autores de manera independiente empleando herramientas de Joanna Briggs Institute. Se estableció como medida de rigor el cumplimiento del 70 % de los criterios a evaluar. Resultados: 13 artículos superaron la valoración de rigor, ocho de tipo cualitativo y seis de cuantitativo, de Europa [1], Sudeste Asiático [3], Sudáfrica [6], Norteamérica [1], Suramérica [1] y Australia [1]. Los estudios muestran que aspectos como cultura, género, conocimiento, metodologías, valores y prejuicios del docente se constituyen en condicionantes de las actitudes del docente frente a la ES. Conclusiones: se evidencia que la clave de una mejor ES, son buenas capacitaciones docentes y el entendimiento de todos los actores de la comunidad para evitar mitos y demás.
Embarazo en la adolescencia: diseño y validación de un instrumento para medir el trabajo intersectorial
Authors: Rincón Méndez Alba Yaneth , Hernández Sánchez Jacqueline , Niño Bautista Lucila , Camargo Figuera Fabio Alberto , Mantilla Uribe Blanca Patricia
Published: September 2022

El trabajo intersectorial en la promoción de la salud es ampliamente reconocido; sin embargo, la literatura consultada evidenció ausencia de instrumentos válidos y confiables en esta área. Objetivo: diseñar y validar un instrumento para medir el trabajo intersectorial en funcionarios públicos que participaron en una Estrategia Nacional de Prevención del Embarazo en la Adolescencia (EPEA). Metodología: 1. Diseño del instrumento a partir de revisión de literatura, antecedentes de trabajo intersectorial en Colombia y experiencia del equipo investigador; 2. Validación facial para medir precisión, pertinencia, claridad y comprensión de los ítems con muestra por conveniencia de 12 personas; 3. Validación del constructo mediante modelo Rasch, sobre muestra de 132 funcionarios públicos. Resultados: el instrumento final conformado por 21 ítems, presentó buenas propiedades de validez facial y de constructo. La consistencia interna fue de 0,92; en el análisis Rasch se excluyeron personas e ítems que no se ajustaron al modelo, logrando correlaciones positivas entre ítems y medidas mayores a 0,47, unidimensionalidad con una varianza explicada por las medidas de 44,6 %; la varianza explicada en el primer contraste de los residuales fue de 5,7 %, la separación de personas fue de 2,07 y de ítems de 4,51 y la dificultad de los ítems estuvo entre -3,14 y 3,69 lógitos. Ninguno de los ítems presentó funcionamiento diferencial. Conclusiones: se cuenta con un instrumento válido y confiable con 21 ítems para la evaluación de competencias en trabajo intersectorial de funcionarios públicos que trabajan en prevención del embarazo en la adolescencia.
Estimation of Glomerular Filtration Rate (GFR) in pregnant women
Authors: Patricia Fernández-Riejos , Catalina Sánchez-Mora , Raquel Galván Toribio , Carmen Odriguez-Chacón , Antonio León-Justel
Published: September 2022

Pregnancy induces marked changes in the cardiovascular and plasma volume regulatory systems. By the end of the first trimester of gestation, the kidneys show marked glomerular hyperfiltration, resulting in a decrease in the patient’s serum creatinine with advancing gestational age [1].
Stereotaxic rat brain surgery for Substantia Nigra targeting v1
Authors: not provided miquel.vila
Published: September 2022

Stereotaxic rat brain surgery
Twist 96-Plex (Riptide) Library Prep v1
Authors: A Cohen Katarina , H Nguyen Khai-Minh , Polesskaya Oksana , Palmer Abraham
Published: September 2022

This protocol is designed for Twist 96-PLex Library Prep. We use the EPmotion 5075 to add sample barcodes (can also easily be done manually with a multichannel pipette). This is a continuation of the "EPMotion - Normalization and Randomization" protocol.
Cylinder behavioral test v1
Authors: not provided miquel.vila
Published: September 2022

Cylinder behavioral testfor left and right forepaw use
Phylogenetic Analysis of Complete Bovine Coronavirus Genome Sequences v2
Authors: M Workman Aspen
Published: September 2022

Bovine coronavirus (BCoV) has spilled over to many species, including humans, where the host range variant coronavirus OC43 is endemic. Balance of the opposing activities of the surface spike (S) and hemagglutinin esterase (HE) glycoproteins control virion avidity which is critical for interspecies transmission and host adaptation. Here, 78 genomes were sequenced directly from clinical samples collected between 2013 and 2022 from cattle in 12 states, primarily in the Midwestern U.S. Relatively little genetic diversity was observed, with genomes having >98% nucleotide identity. Eleven isolates collected between 2020 and 2022 from four states (Nebraska, Colorado, California, and Wisconsin) contained a 12-nucleotide insertion in the receptor-binding domain (RBD) of the HE gene identical to one recently reported in China, and a single genome from Nebraska collected in 2020 contained a novel 12-nucleotide deletion in the HE gene RBD. Isogenic HE proteins containing either the insertion or deletion in the HE RBD maintained esterase activity and the ability to bind bovine submaxillary mucin, a substrate enriched in the receptor 9-O-acetylated-sialic acid, despite modeling that predicted structural changes in the HE R3 loop critical for receptor binding. The emergence of BCoV with structural variants in the RBD raises the possibility of further interspecies transmission.
Mechanisms of oxidative stress in the pathogenesis of chronic bacterial prostatitis (literature review)
Authors: Bratchikov O. I. , Dubonos P. A. , Tyuzikov I. A. , Schumakova E. A.
Published: September 2022

The review article, based on the results of modern clinical and experimental studies, discusses general issues of the pathophysiology of oxidative stress as a universal pathogenetic factor of human diseases and particular pathophysiological aspects of oxidative stress on the example of chronic bacterial prostatitis. Separately, the most studied mechanisms of oxidative stress in the pathogenesis of the infectious and inflammatory process associated with chronic bacterial prostatitis are highlighted, which contribute to the occurrence and persistence of oxidative disorders in the prostate gland and disrupt the full restoration of its anatomical and functional state after inflammation with a potentially negative effect on the results of standard chronic bacterial prostatitis pharmacotherapy.
Histogram analysis for the differentiation of malignant and benign lesions in breast magnetic resonance imaging: preliminary study
Authors: AĞLAMIŞ Serpil , BAYKARA Murat
Published: September 2022

Purpose: The present study assesses whether malignant and benign lesions can be distinguished through histogram analysis of non-fat-suppressed T1-weighted and fat-suppressed T2-weighted breast magnetic resonance images (MRIs).

Materials and Methods: MRIs of 20 malignant and 20 benign breast lesions were reviewed retrospectively by histogram analysis performed using Osirix V.4.9 software. The regions of interest (ROIs) were drawn manually to include almost the entire lesion, and values from these ROIs were used to calculate gray-level intensity mean, standard deviation, entropy, uniformity, skewness, kurtosis, and percentile values.

Results: In non-fat-suppressed T1-weighted images, the minimum, 1st, 3rd, 5th, 10th and 25th percentile values were significantly lower in the malignant lesions than in the benign lesions. The minimum value had sensitivity of 70% and specificity of 63.2%. On the fat-suppressed T2-weighted images, skewness was significantly higher while uniformity was significantly lower in malignant lesions than benign lesions. Skewness had 68.4% sensitivity and 60% specificity, and uniformity had 65% sensitivity and 68.4% specificity.

Conclusion: The results of this study demonstrated that histogram analysis of non-fat-suppressed T1-weighted and fat-suppressed T2-weighted images can be used to differentiate malignant and benign lesions in breast MRI.
The effect of CYP2C9 gene polymorphisms on blood pressure lowering response to losartan in patients with essential hypertension
Authors: PEPEDİL TANRİKULU Funda , BABAOGLU Melih O. , ÇAKIR Banu , BOZKURT Atilla , GÜVEN Gülay Sain
Published: September 2022

Purpose: In this study, the possible effects of CYP2C9 polymorphisms on the clinical response to losartan were investigated in a group of hypertensive patients.

Materials and Methods: Seventy-four patients, newly diagnosed to have essential hypertension, and were subsequently prescribed losartan by attending physicians, were prospectively recruited for the study. Blood pressure measurements at the initiation of losartan treatment and six weeks after were completed for all participants. Genetic analysis for CYP2C9 polymorphisms was performed in blood samples collected at baseline. CYP2C9 *2 and *3 variant alleles were genotyped, and polymorphic patients' treatment responses were compared with the patients' who were carrying the wild type genotype.

Results: Analysis comparing the wild type genotype and CYP2C9*1*2 genotype revealed a trend toward more systolic blood pressure reduction in favor of wild-type genotype. However, there was no statistically significant difference between these two groups considering the change in diastolic blood pressure levels. Regarding the CYP2C9*1*3 genotype, there were no significant differences in systolic or diastolic blood pressure changes.

Conclusion: CYP2C9*1*2 polymorphism affects the systolic blood pressure response to losartan in hypertensive patients, while the CYP2C9*1*3 genotype was not shown in associated with systolic or diastolic blood pressure responses.

Keywords: Hypertension, losartan, CYP2C9, genetic polymorphism, pharmacogenetics
Cinsel istismara uğrayan ergenlerde bağlanma stili, ana-baba tutumu, depresyon ve anksiyetenin değerlendirilmesi
Authors: KELEŞ Şeyma , TOROS Fevziye , GÜLER AKSU Gülen , İNCEL İpek
Published: September 2022

Amaç: Bu çalışmada cinsel istismar mağduru ergenlerin sosyodemografik özelliklerinin ve uğradıkları cinsel istismarın özelliklerinin tanımlanması; bununla birlikte bu ergenlerin bağlanma stillerinin, ana-baba tutumlarının, depresyon ve anksiyete ölçek puanlarının cinsel istismara uğramayan kontrol grubu ile karşılaştırılması amaçlanmıştır.

Gereç ve Yöntem: Araştırmanın örneklemini 13-18 yaş grubundaki cinsel istismara uğrayan 34 ergen ve cinsel istismara uğramayan 34 ergen oluşturmaktadır. Çalışmaya katılan tüm ergenlerin sosyodemografik verileri toplanmıştır. Cinsel istismara uğrayan ve uğramayan ergenlerin bağlanma stillerini, ebeveyn tutumlarını, depresyon ve anksiyete şiddetini karşılaştırmak için İlişki Ölçekleri Anketi, Ana-baba Tutum Ölçeği, Çocuklar için Depresyon Ölçeği ve Durumluk-Süreklilik Kaygı Envanterinden yararlanılmıştır.

Bulgular: Olguların yaş ortalaması 15,29±1,31 olarak saptanmıştır. Cinsel istismar grubunun korkulu bağlanma alt ölçek puan ortalamaları kontrol grubuna göre anlamlı olarak daha yüksek bulunmuştur. Cinsel istismar grubunun kontrol grubuna göre ebeveyn tutumları açısından otoriter tutum alt ölçek ortalamalarının anlamlı olarak yüksek olduğu görülmüştür. Cinsel istismar grubunun depresyon ve durumluk-süreklilik anksiyete puan ortalamasının kontrol grubuna göre anlamlı olarak yüksek olduğu da saptanmıştır.

Sonuç: Cinsel istismara uğrayan çocuk ve ergenlerin sosyodemografik özelliklerinin, istismara ait özelliklerin ve risk faktörlerinin tanımlanması, anne ve çocuk etkileşiminin arttırılması, güvenli bağlanmanın gerçekleşmesine yönelik ana-baba eğitimlerinin olması, demokratik ana-baba tutumunun benimsenmesi çocuk ve ergenlerin ruh sağlığını korumak açısından son derece önemlidir.
Is neuropathic pain an overlooked symptom in axial spondyloarthritis?
Authors: KAYACAN ERDOĞAN Esra , TÜRK İpek
Published: September 2022

Purpose: Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatologic disease. Pain is the most common symptom affecting quality of life in axSpA patients. It has been showed that pain is not always correlated with inflammation in patients. The aim of our study was to investigate the frequency of neuropathic pain in axSpA patients and relationship between neuropathic pain and patient characteristics.

Materials and Methods: Patients diagnosed as axSpA according to the Assessment of SpondyloArthritis International Society classification criteria, who presented in our outpatients clinics from January to March 2019 were included in this study. The neuropathic component of pain was evaluated with Douleur Neuropathique en 4 Questions (DN4) questionnaire.

Results: Eighty seven axSpA patients were included in the study. Thirty of patients had neuropathic pain according to DN4 questionnaire (DN4>4). Neuropathic pain was higher in active disease group depending on both of ASDAS-CRP and BASDAI. DN4 score of patients was found moderately correlated with ASDAS-CRP and BASDAI score. A weak positive correlation was found between patients education level and DN4 score.

Conclusion: We showed that neuropathic pain could be seen in patients with axSpA and it could be correlated with disease activity. The studies have proven that neuropathic pain could lead to impaired quality of life and social & emotional functions. Patients with neuropathic pain could not benefit from antiinflammatory treatments. Therefore evaluating of neuropathic pain is important in axSpA patients. Further studies on management of neuropathic pain in axSpA patients are needed.
Multipl sklerozda spinal kord lezyonları ile kognisyon ilişkisi
Authors: DİKER Sevda , EKER Amber , KAYMAKAMZADE Doç Dr Bahar , EREM Aysegul , BALYEMEZ Uğurcan
Published: September 2022

Amaç: Çalışmamızda, multipl skleroz (MS)da fiziksel özürlülük ve prognozla yakın ilişkisi olan spinal kord tutulumunun, kognitif işlevler üzerine olası etkisi incelenmiştir.

Gereç ve Yöntem: Çalışmaya 29 MS hastası (2 klinik izole sendrom, 23 relaps ve remisyonlarla seyreden MS, 2 sekonder progresif MS, 2 primer progresif MS) alındı. Demografik özellikleri, genişletilmiş özürlülük durum skalası (EDSS) skoru, Rao’nun kısa tekrarlanabilir nöropsikolojik test bataryası ile değerlendirilen kognitif durumu, beyin ve spinal kord T2 lezyon sayısı değerlendirildi. Benzer demografik özelliklere sahip 17 sağlıklı kontrol ile kognitif test sonuçları karşılaştırıldı.

Bulgular: İleri yaş, hastalık başlangıç yaşının ileri olması, kısa eğitim süresi kognitif test sonuçlarını olumsuz etkileyen özelliklerdir. Beyin ve spinal kord lezyon sayılarının kognitif testler üzerine anlamlı etkisi saptanmamıştır. Spinal kord lezyonu olan hastalar olmayanlara göre daha yüksek EDSS’ye sahiptir, ancak iki grup arasında kognitif test sonuçları açısından anlamlı farklılık saptanmamıştır.

Sonuç: Spinal kord lezyonları, EDSS ile değerlendirilen fiziksel özürlülük ile ilişkilidir. Kord plak varlığının ya da sayısının kognitif test sonuçları üzerine etkisini, servikal kord atrofisi ile birlikte değerlendirecek, daha geniş örneklemli boylamsal çalışmalara ihtiyaç vardır.