bluuebunny/crossref_metadata_2025 huggingface dataset:
O conjunto de Mandelbrot usando Python
Authors: Frediani João Otávio Rodrigues Ferreira , De Souza Tatiana Miguel Rodrigues
Published: December 2020

A Natureza em geral é constituída por formas nas quais predominam a irregularidade e o caos. Tentar simplificá-las usando figuras da geometria clássica seria inadequado. A Geometria Fractal, na qual se torna possível o surgimento de objetos com dimensão fracionária, oferece um método para analisar e descrever objetos e formas naturais, contrapondo-se às limitações da geometria euclidiana. Neste trabalho será apresentado o Conjunto de Mandelbrot obtido através da linguagem Python.
The effect of lending policy on the profitability of commercial banks: Evidence from Jordan
Authors: Al-hawatmah Zaid , Shaban Osama Samih
Published: December 2020

This study aims to find out the impact of the lending policies adopted by Jordanian commercial banks on their profitability. This study relied on the descriptive analytical approach to describe and review the theoretical framework of the study. The preliminary information was gathered through a questionnaire prepared for this purpose. The study population consisted of all the commercial banks operating in Jordan, numbering 13 banks during the period 2016-2020. The study concluded that the credit decisions in the Jordanian commercial banks are contributing to about 75.3% of their returns, and there is a statistically significant effect of lending policies (with their combined variables) on the profitability of commercial banks operating in Jordan. Also, the lending policies adopted by the Jordanian commercial banks have interpreted 53.9% of their profitability, and that is due to the strict lending policy adopted by these banks, and this result is adverse of Munyiri’s (2010) results stating that a friendly lending policy will maximize demand and increases bank’s profitability. Depending on the results, the study recommended that the Jordanian commercial banks should focus on a clearly allocated task, responsibilities, and powers within credit policies so that different administrative levels are granted the right to make high-quality credit decisions that enhance the speed of taking a decision, thereby increasing customer’s base and profits.
Butyrate ameliorate skeletal muscle atrophy in Diabetic Nephropathy via enhancing gut barrier function and GPR43 mediated PI3K/AKT/mTOR signals
Authors: Tang Gang , Du Yi , Guan Haochen , Jia Jieshuang , Zhu Nan , Shi Yuping , Rong Shu , Yuan Weijie
Published: December 2020

Muscle protein catabolism in patients with diabetic nephropathy (DN)
results in striking losses of muscle proteins, which increases morbidity
and mortality risks. Emerging evidence shows that short-chain fatty
acids (SCFAs) play an important role in the maintenance of health and
disease development. Recently, the connection between butyrate (a SCFA)
and DN has been revealed, although the relationship between butyrate and
muscle atrophy is still not clear. In our study, we found a significant
decrease in butyrate in DN using metabolomics analyses. The addition of
butyrate remarkably intestinal barrier function. Concurrently, butyrate
could alleviate muscle atrophy and promote PI3K/AKT/mTOR signals, and
suppress oxidative stress and autophagy in the skeletal muscle of db/db
mice as well as high glucose/lipopolysaccharide (HG/LPS)-induced C2C12
cells. To further explore the mechanism, we found that GPR43, the key
SCFAs signaling molecule, was significantly decreased in the skeletal
muscle of db/db mice and HG/LPS-induced C2C12 cells. Overexpression of
GPR43 could activate PI3K/AKT/mTOR signals and inhibit oxidative stress
and autophagy in HG/LPS-induced C2C12 cells. Silencing of GPR43 blocked
PI3K/AKT/mTOR signals improved by butyrate, as well as suppression of
oxidative stress and reduction of autophagy. Ultimately, butyrate
alleviated muscle atrophy in DN via GPR43-mediated PI3K/AKT/mTOR pathway
A practical approach for applying Machine Learning in the detection and classification of network devices used in building management
Authors: Touma Maroun , Witherspoon Shalisha , Witherspoon Shonda , Crawford-Eng Isabelle
Published: December 2020

With the increasing deployment of smart buildings and infrastructure,
Supervisory Control and Data Acquisition (SCADA) devices and the
underlying IT network have become essential elements for the proper
operations of these highly complex systems. Of course, with the increase
in automation and the proliferation of SCADA devices, a corresponding
increase in surface area of attack on critical infrastructure has
increased. Understanding device behaviors in terms of known and
understood or potentially qualified activities versus unknown and
potentially nefarious activities in near-real time is a key component of
any security solution. In this paper, we investigate the challenges with
building robust machine learning models to identify unknowns purely from
network traffic both inside and outside firewalls, starting with missing
or inconsistent labels across sites, feature engineering and learning,
temporal dependencies and analysis, and training data quality (including
small sample sizes) for both shallow and deep learning methods. To
demonstrate these challenges and the capabilities we have developed, we
focus on Building Automation and Control networks (BACnet) from a
private commercial building system. Our results show that ”Model Zoo”
built from binary classifiers based on each device or behavior combined
with an ensemble classifier integrating information from all classifiers
provides a reliable methodology to identify unknown devices as well as
determining specific known devices when the device type is in the
training set. The capability of the Model Zoo framework is shown to be
directly linked to feature engineering and learning, and the dependency
of the feature selection varies depending on both the binary and
ensemble classifiers as well.
Levothyroxine-associated lichenoid drug eruption: A case report and review of levothyroxine-induced adverse reactions
Authors: Hu Nianfang , Long Yajing , Xian Yan , Li Yong
Published: December 2020

Levothyroxine (LT4) is frequently used as thyroid hormone replacement to
treat hypothyroidism. Adverse skin reactions are not common. Lichenoid
drug eruption is a one such medication-related reaction. the lesion
morphology and pathology mimic lichen planus. The current case describes
a 47-year-old man who presented to us with a diffuse
levothyroxine-induced lichenoid drug eruption. The Naranjo adverse drug
reaction probability assessment score suggested this was likely an ADR
to levothyroxine. The eruption resolved after discontinuation of the
medication. We also reviewed the literature on levothyroxine-associated
adverse events.
The spectrum of ATM gene mutations in Iranian patients with ataxia-telangiectasia
Authors: Amirifar Parisa , Ranjouri Mohammad Reza , Pashangzadeh salar , Lavin Martin , Yazdani Reza , Shad Tannaz Moeini , Mehrmohamadi Mahya , Salami Fereshte , Delavari Samaneh , Moamer Soraya , Aghamohammadi Asghar , Akrami Seyed Mohammad , Abolhassani Hassan
Published: December 2020

Abstract Background: Ataxia-telangiectasia (A-T) is a rare genetic
disorder characterized by a distinct range of clinical manifestations,
including progressive ataxia, immunodeficiency, and radiosensitivity.
Methods: Clinical data, laboratory results, and genetic data were
collected from forty-three A-T patients. Whole exome sequencing and
Sanger sequencing were done for the patients clinically diagnosed as
suffering from A-T. Based on the phenotype severity of the disease,
patients were divided into severe and mild sub-groups. Results: The
median (IQR) age of diagnosis in this cohort was 5 (3-7) years and
various types of clinical manifestations, including fever (p= 0.005),
lower respiratory tract infection (p= 0.033), diarrhea (p= 0.014), and
hepatosplenomegaly (p= 0.032) were significantly higher amongst patients
diagnosed with the severe phenotype. Our results showed a strong
correlation between phenotype severity and mutation type. The chance of
having severe phenotype in patients who have severe mutations, including
frameshift and nonsense, was 7.3 times higher compared to patients who
were categorized in the mild genotype group (odds ratio= 7.3, p= 0.006).
Thirty-four types of mutations including 9 novel mutations, were
observed in our study. Conclusion: Molecular analysis provides the
opportunity for accurate diagnosis and timely management in A-T patients
with chronic progressive disease, especially infections and the risk of
malignancies. This study characterizes for the first time, the broad
spectrum of mutations and phenotypes in Iranian A-T patients which are
required for carrier detection and reducing the burden of disease in
future using the patients’ families and for the public health care
system. Keywords: Ataxia-telangiectasia (A-T), ATM, Whole-exome
sequencing, Class switching recombination (CSR), phenotype severity.
Investigating the role of noncoding regulatory DNA in plasmid development for Yarrowia lipolytica
Authors: Lopez Carmen , Cao Mingfeng , Yao Zhanyi , Shao Zengyi
Published: December 2020

Production of industrially relevant compounds in microbial cell
factories can employ either genomes or plasmids as an expression
platform. Selection of plasmids as pathway carriers is advantageous for
rapid demonstration but poses a challenge of stability. Yarrowia
lipolytica has attracted great attention in the past decade for the
biosynthesis of chemicals related to fatty acids at titers attractive to
industry, and many genetic tools have been developed to explore its
oleaginous potential. Our recent studies on the autonomously replicating
sequences (ARSs) of nonconventional yeasts revealed that the ARSs from
Y. lipolytica showcase a unique structure that includes a previously
unannotated sequence (spacer) linking the origin of replication (ORI)
and the centromeric (CEN) element and plays a critical role in
modulating plasmid behavior. Maintaining a native 645-bp spacer yielded
a 4.5-fold increase in gene expression and higher plasmid stability
compared to a more universally employed minimized ARS. Testing the
modularity of the ARS sub-elements indicated that plasmid stability
exhibits a pronounced cargo dependency. Instability caused both plasmid
loss and intramolecular rearrangements. Altogether, our work clarifies
the appropriate application of various ARSs for the scientific community
and sheds light on a previously unexplored DNA element as a potential
target for engineering Y. lipolytica.
Information and thermodynamics properties of a non-Hermitian particle ensemble
Authors: Lima Francisco Cleiton , Moreira Allan , ALMEIDA CARLOS ALBERTO
Published: December 2020

In the context of non-relativistic quantum mechanics, we use information theory to study Shannon’s entropy of a non-Hermitian system and understand how the information is modified with the cyclotron frequency. Subsequently, we turn our attention to the construction of an ensemble of these spinless particles in the presence of a uniform magnetic field. Then, we study the thermodynamic properties of the model. Finally, we show how information and thermodynamic properties are modified with the action of the magnetic field.Keywords: Non-relativistic Quantum Mechanics; Quantum Information; Shannon Entropy.
Further results on the outer connected geodetic number of a graph
Authors: Ganesamoorthy Kathiresan , Jayanthi Duraisamy
Published: December 2020

For a connected graph G of order at least two, an outer connected geodetic
set S in a connected graph G is called a minimal outer connected geodetic set
if no proper subset of S is an outer connected geodetic set of G. The upper
outer connected geodetic number g+ oc(G) of G is the maximum cardinality of a
minimal outer connected geodetic set of G. We determine bounds for it and
find the upper outer connected geodetic number of some standard graphs. Some
realization results on the upper outer connected geodetic number of a graph
are studied. The proposed method can be extended to the identification of
beacon vertices towards the network fault-tolerant in wireless local access
network communication. Also, another parameter forcing outer connected
geodetic number fog(G) of a graph G is introduced and several interesting
results and realization theorem are proved.
A High-Fat Diet Attenuates Amp-Activated Protein Kinase α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development in Vivo
Authors: Admin Ada , Yan Chenghui , Tian Xiaoxiang , Li Jiayin , Liu Dan , Ye Ding , Xie Zhonglin , Han Yaling , Zou Ming-Hui
Published: December 2020

Exosomes are important for intercellular communication, but the role of exosomes
in the communication between adipose tissue (AT) and
the liver remains unknown. The aim of this study is to determine the
contribution of AT-derived exosomes in nonalcoholic fatty liver disease (NAFLD). Exosome components, liver fat content, and liver
function were monitored in AT in mice fed a high-fat
diet (HFD) or treated with metformin- or GW4869
and with AMP-activated protein kinase (AMPKα1) floxed (Prkaα1fl/fl/WT), Prkaα1-/-,
liver tissue-specific Prkaα1-/-, or AT-specific Prkaα1-/-
modification. In cultured adipocytes and white adipose tissue (WAT), the
absence of AMPKα1
increased exosome release and exosomal proteins by elevating tumor susceptibility gene 101 (TSG101)-mediated exosome biogenesis. In adipocytes treated with
palmitic acid, TSG101 facilitated scavenger receptor class B (CD36) sorting
into exosomes. CD36-containing exosomes were then endocytosed by hepatocytes to
induce lipid accumulation and inflammation. Consistently, an HFD induced more
severe lipid accumulation and cell death in Prkaα1-/-
and adipose tissue-specific Prkaα1-/- mice than in WT and
liver-specific Prkaα1-/- mice. AMPK activation by metformin
reduced adipocyte-mediated exosome release and mitigated fatty liver
development in WT and liver specific Prkaα1-/- mice.
Moreover, administration of the exosome inhibitor GW4869 blocked exosome
secretion and alleviated HFD-induced fatty livers in Prkaα1-/-
and adipocyte-specific Prkaα1-/- mice. We conclude that HFD-mediated
AMPKα1 inhibition promotes NAFLD by increasing numbers of AT CD36-containing exosomes.
Kompresi Citra dengan menggunakan Metode Delta Modulation
Authors: Ardiyanto Didik , Purwoto Bambang Hari
Published: December 2020

Kompresi citra merupakan suatu teknik yang digunakan untuk mengurangi biaya penyimpanan dan transmisi. Pemampatan atau kompresi citra merupakan suatu metode yang sangat bermanfaat bagi perkembangan citra digital. Dengan kompresi, data citra digital yang ukurannya besar, dapat dikompres sehingga mempunyai ukuran yang lebih kecil. Program kompresi citra dengan metode delta modulation ini, dibuat dengan GUI dan source coding. Dengan menerapkan fungsi dari Dmsig untuk pengolahan sinyal, maka didapatkan rumus untuk mengkompres gambar yang dipengaruhi oleh step size dan ukuran gambar tersebut. Kelebihan dari teknik Delta Modulation adalah dapat mengkompres gambar grayscale, black and white dan true color. Hasil gambar yang sudah dikompres menunjukkan bahwa metode ini baik untuk menghasilkan gambar dengan output berformat jpg,png dan tiff. Kualitas gambar yang paling baik dari hasil kompresi delta modulation yaitu gambar berformat jpg. Untuk tingkat kompresi yang paling bagus juga ada pada gambar berformat jpg, ini diambil berdasarkan nilai MSE dan PSNR yang di hitung pada gambar hasil kompresi. Tingkat kompresi dengan delta modulation termasuk tinggi karena masuk ke lossy compression.
Aplikasi Alat Musik Gamelan Jawa pada Perangkat Android
Authors: Sumirat Putra Adi
Published: December 2020

Gamelan Jawa merupakan suatu peninggalan kebudayaan Indonesia yang semakin tergeser oleh masukkya kebudayaan barat yang mempengaruhi cara bermusik masyarakat Indonesia. Maka dari itu perlu dibuat Gamelan Jawa dalam bentuk yang baru agar kesenian ini dapat dilestarikan dengan cara yang modern. Salah satunya adalah, dengan membuat aplikasi Gamelan Jawa pada perangkat smartphone berbasis android. Metode penelitian yang dilakukan pertama adalah merekam suara dan mengambil foto Gamelan, kemudian suara diolah dengan software Audacity untuk memotong setiap notasi Gamelan. Tahap selanjutnya adalah mendesain sistem dengan software Eclipse yang sudah terpasang ADT, kemudian sistem diuji dengan SDK. Dan untuk desain gambar Gamelan menggunakan software Adobe Potoshop serta untuk mengedit audio menggunakan software Audacity. Aplikasi Gamelan Jawa berbasis android ini memiliki tujuh pasang Gamelan laras slendro dan pelog, serta satu buah kendang siter. sistem dalam aplikasi ini dapat menghasilkan suara Gamelan yang diinginkan jika ikon pada aplikasi tersebut disentuh. Perangkat aplikasi ini juga dapat dimainkan dengan dua jari yang memungkinkan dua suara yang berbeda pada saat yang bersamaan.
Pemanfaatan Solar Cell dengan PLN sebagai Sumber Energi Listrik Rumah Tinggal
Authors: Asy'ari Hasyim , Rozaq Abdul , Putra Feri Setia
Published: December 2020

Sejak tahun 2013 Pemertinah menaikkan harga tariff dasar listrik sebesar 15%, kenaikan dilakukan secara bertahap setiap 3 bulan sekali. Kenaikan tarif dasar listrik berlanjut di tahun 2014, awal mei 2014 semua pelanggan minimal 1300 Va dikenakan kenaikan sebesar 4%, langkah ini diakibatnya semakin besar subsidi energi listrik oleh PLN yang mengalmai kerugian, salah satu penyebab kerugian PLN tersebut adalah mahalnya biaya operasional untuk pembelian bahan bakar pembangkit. Penggunaan energi terbarukan merupakan alternative untuk mengurangi permintaan energi ke PLN dan pengoptimalan potensi alam. Sel surya merupakan teknologi yang mengubah cahaya matahari menjadi energi listrik. Besarnya energi yang mampu dihasilkan oleh sel surya untuk kebutuhan rumah tangga merupakan tujuan dari penelitian ini, adapun metode penelitian ini adalah pengukuran energi yang mampu disuplai oleh energi yang dihasilkan oleh sel surya, penelitian ini menggunakan 2 buah modul sel surya dengan kapasitas masing-masing adalah 100 Wattpeak, Controller 12/24 Volt DC dengan kapasitas 60 A, Accumulator dengan kapasitas 100 Ah dan Inverter dengan kapasitas 500 Watt, Lampu DC Philips 5 Watt, 10 Watt, 13 Watt dan Lampu 5 buah SL 18 Watt. Selama pengujian menunjukkan bahwa arus yang diproduksi paling tinggi terjadi sekitar jam 12.30, dengan nilai arus sebesar 13 A dan tegangan 14 Volt DC. Energi yang dihasilkan pada siang hari digunakan untuk mensuplai beban lampu mulai dari pukul 17.00 – 06.00 dengan rerata setiap malam energi yang dapat digunakan sebesar 1,027 Kwh.
Chemical Analysis and the Study of Quality Indicators of the Immunobiological Drug for Preventing and Treating Candidal Infections
Authors:   Department of Biotechnology, National University of Pharmacy, Kharkiv, Ukraine, Rybalkin Mykola , Strelnikov Leonid ,   Department of Biotechnology, National University of Pharmacy, Kharkiv, Ukraine, Strilets Oksana ,   Department of Biotechnology, National University of Pharmacy, Kharkiv, Ukraine, Kaliuzhnaia Olha ,   Department of Biotechnology, National University of Pharmacy, Kharkiv, Ukraine, Kutsenko Sergiy ,   Department of Industrial Technology of Drugs, National University of Pharmacy, Kharkiv, Ukraine
Published: December 2020

Quality indicators such as protein content, polysaccharide content, phenol content, and pH of the developed vaccine solution for injection (VSI) “Candidocyde” based on cells of C. albicans and C. tropicalis fungi have been found to meet the standard requirements. It was determined that by the indicator of transparency and degree of turbidity the test solution is transparent, by the coloration degree it is colorless, by the sterility indicator it is sterile. The sterility period, determined after the first opening, is 8 hours. It was found that no solid particles were present in the solution; the container with the solution is hermetic; the volume of the container with a solution is not less than 5.0 ml. The test solution is stable for 2 years of storage at 275-265 K.
Direct Synthesis and Characterization of Photo-Crosslinkable Biodegradable PLA-PEG-PLA Ttiblock Copolymer with Methacrylates Functions by Green Montmorillonite Clay Catalyst
Authors:   Laboratoire de Chimie des Polymères, Département de Chimie, FSEA, University of Oran 1 Ahmed Benbella BP N° 1524 El M’Naouar, 31000 Oran, Algeria, Benachour Mohamed , El-Kebir Aslya ,   Laboratoire de Chimie des Polymères, Département de Chimie, FSEA, University of Oran 1 Ahmed Benbella BP N° 1524 El M’Naouar, 31000 Oran, Algeria, Harrane Amine ,   Laboratoire de Chimie des Polymères, Département de Chimie, FSEA, University of Oran 1 Ahmed Benbella BP N° 1524 El M’Naouar, 31000 Oran, Algeria,   FSEI University of Abdelhamid Ibn Badis – Mostaganem, Meghabar Rachid ,   Laboratoire de Chimie des Polymères, Département de Chimie, FSEA, University of Oran 1 Ahmed Benbella BP N° 1524 El M’Naouar, 31000 Oran, Algeria, Belbachir Mohammed ,   Laboratoire de Chimie des Polymères, Département de Chimie, FSEA, University of Oran 1 Ahmed Benbella BP N° 1524 El M’Naouar, 31000 Oran, Algeria
Published: December 2020

Di-methacrylated PLA-PEG-PLA triblock copolymers of polylactide and polyethylene glycol were synthesized in one-step process by bulk cationic polymerization of lactide in the presence of PEG with different average molecular weights, using Maghnite-H+, an acidic montmorillonite clay, as a solid non-toxic catalyst. The obtained di-methacrylated copolymer was analyzed by 1H NMR and DSC. The effect of Maghnite-H+ proportions and PEG average molecular weight on the copolymerization and methacrylation yields and on average molecular weight of the resulting copolymers was studied.
Cosolvents Impact on some Properties of the Solutions and the Films of Succinamide Chitosan
Authors:   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan, Bazunova Marina , Chernova Valentina ,   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan, Lazdin Roman ,   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan, Shurshina Angela ,   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan, Bazunova Anna ,   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan, Elinson Mariya ,   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan, Kulish Elena ,   Bashkir State University 32, Zaki Validi St., 450076 Ufa, Republic of Bashkortostan
Published: December 2020

The article deals with the method of the medical purpose materials creation with the controlled physico-chemical and mechanical deformation properties on the basis of water-soluble derivative of amino polysaccharide chitosan – succinamide chitosan. The essence of the method is the macromolecules aggregation processes regulation in the initial solutions by the injection of organic cosolvents – acetone and ethanol. It has been stated that in a mixed solvent succinamide chitosan molecules are not in the form of the isolated macromolecular balls but as the macromolecules interacting (aggregated) systems. It has been proved that the presence of cosolvents decreases the polymer macromolecule links capability to interact with an enzyme and increases physico-mechanical characteristics of the film materials.
Epoxy Composites Filled with Natural Calcium Carbonate. 3. Epoxy Composites Obtained in the Presence of Monocarboxylic Derivative of Epidian-6 Epoxy Resin
Authors:   Lviv Polytechnic National University 12, S.Bandery St., 79013 Lviv, Ukraine, Bratychak Michael , Astakhova Olena ,   Lviv Polytechnic National University 12, S.Bandery St., 79013 Lviv, Ukraine, Shyshchak Olena ,   Lviv Polytechnic National University 12, S.Bandery St., 79013 Lviv, Ukraine
Published: December 2020

A monocarboxylic derivative of Epidian-6 with free epoxy and carboxylic end groups (MCDER) has been synthesized using Epidian-6 epoxy resin and sebacic acid. The structure of MCDER was confirmed by a spectral analysis. The thermal stability of MCDER has been established and the formation of cross-linked films based on epoxy-oligomeric mixtures consisting of Epidian-5, TGM-3 oligoesteracrylate, and polyethylene polyamine has been studied in its presence. By means of IR spectroscopy, the chemistry of the mixtures formation has been established. Physico-mechanical characteristics and morphology of the epoxy-oligomeric mixture based samples which were filled with CaCO3 have been determined.
Microcrystalline Cellulose from Groundnut Shell as Potential Adsorbent of Crystal Violet and Methylene Blue. Kinetics, Isotherms and Thermodynamic Studies
Authors:   Department of Fundamental and Applied Sciences, Universiti Teknologi PETRONAS, 32610, Seri Iskandar, Perak, Malaysia, Zango Zakariyya Uba ,   Department of Chemistry, Al-Qalam University Katsina, P.M.B 2341, Katsina, Nigeria, Imam Saifullahi Shehu ,   School of Chemical Sciences, Universiti Sains Malaysia, 11800, Pulau Penang, Malaysia,   Departmentof Pure and Industrial Chemistry, Bayero University, P.M.B 3011, Kano, Nigeria
Published: December 2020

The isolation of microcrystalline cellulose from a groundnut shell is reported. Adsorption experiments were carried out for the removal of cationic crystal violet and methylene blue and it follows Langmuir model. Positive enthalpy and negative free energy changes have shown endothermic and favorable processes. The results reflect good adsorption process.
Exploiting Response Surface Methodology (RSM) as a Novel Approach for the Optimization of Phenolic and Antioxidant Activity of Date Palm Fruit
Authors:   Laboratoire des Sciences Fondamentale, Université Amar Telidji, Laghouat, Algérie, Hachani Soumaya , Boukhalkhal Sarah ,   Laboratoire des Sciences Fondamentale, Université Amar Telidji, Laghouat, Algérie, Ahmed Ziyad Ben ,   Laboratoire des Sciences Fondamentale, Université Amar Telidji, Laghouat, Algérie, Harrat Mohamed ,   Laboratoire des Sciences Fondamentale, Université Amar Telidji, Laghouat, Algérie, Silva Artur M.S. ,   Department of Chemistry and QOPNA, University of Aveiro, 3810-193 Aveiro, Portugal, Yousfi Mohamed ,   Laboratoire des Sciences Fondamentale, Université Amar Telidji, Laghouat, Algérie
Published: December 2020

The Box-Behnken design was used to investigate the effect of three independent variables – time, temperature and solvent-to-solid ratio on the responses of total phenolics, total flavonoids, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and cupric ion reducing antioxidant capacity (CUPRAC) of date fruit methanolic extracts. Response surface analysis showed that the optimal ultrasound extraction parameters that maximized the responses were 30 min, 298 K and 74.4 ml/g. Under optimum conditions, UHPLC-DAD-MS/MS was used to tentatively characterize 11 phenolic compounds. The experimental values for the quantification of phenolic compounds and antioxidant activities are in accordance with the predicted values, indicating the suitability of the model and the success of response surface methodology in optimizing the ultrasound extraction conditions.
Development and investigation of device for processing polymer materials by 3D-printing method
Authors:   Khmelnytskyi National University, Zozulia Petro , Polishchuk Oleg ,   Khmelnytskyi National University, Kostyuk Nazar ,   Khmelnytskyi National University, Polishchuk Andriy ,   Khmelnytskyi National University
Published: December 2020

The analysis of the current state of 3d industry and prospects for its future. In the work, calculations were made and graphs of dependence were obtained, which influence the work of the auger and the installation itself. A new method of printing parts with polymer granules is described and the principle of operation of the equipment used is described. The picture of the working installation with the main components and the method of its attachment on a 3D printer is presented. The heating modes of the extruder itself are simulated and a thermal diagram of the device is shown, which accurately displays the temperature distribution across the sections.
Modeling of “combined cutter - cone” connection in tricone drill bits
Authors:   Lviv Polytechnic National University, Slipchuk Andrii , Kuk Andrii ,   Lviv Polytechnic National University, Kusyi Yaroslav ,   Lviv Polytechnic National University
Published: December 2020

A theoretical analysis of the stiffness of the “cutter-cone” connection was performed. In the article the character and magnitude of the tension at the contact of "cutter-cone" are investigated. An analysis of the surface of the openings for carbide inserts revealed traces of plastic deformation and fretting wear. Since the contact bond of the cutter with the body of cone is the only factor that provides the strength of the connection, let consider the effect of mechanical properties of the cones body and a cutter on the magnitude of the forces of contact and tension in the connection. The surface of the shaft of this design consists of equal parts of solid alloy and steel. If you make a ring at a smaller diameter of the shank of a carbide cutter, this will increase the reliability of the connection of the insertion with the body of the rock cutting tool, optimize toughness of cutter fastening, and ensure high stability of the hard-alloyed inset cutter before fracture. As a result of the conducted researches, a qualitative correlation between the hardness of the carbide insertion fastening in the holes of cone and the nature of the destruction of the carbide cutters has been established. Due to the conducted research, the character of the distribution of contact tensions in the conjugated areas “combined cutter - a hole of cone” was established. The theme of the development of new rational constructions of rock-destructive equipment of cones, rock-destructive inserts, schemes of its effective arrangement on the brushes of cone is still actual. A separate issue of further research is the study of functional and energy interaction of elements of propulsion and rock-destructive equipment.
Surface Treatment of Zirconia Implant, Its Surface Roughness and Its Effect on Osseointegration - A Review
Authors: Meshramkar Roseline , Shetty Praveen , Nayak Aishwarya , Anehosur Gouri V.
Published: December 2020

Zirconia implant treatment is currently overriding other prosthetic solutions in replacing anterior teeth in esthetic zone. Surface topography of biomaterial has major impact on osseointegration. Various chemical and physical modifications have been developed to improve osseointegration. This review focuses on different surface treatment of zirconia implant. Surface roughness and its effect on osseointegration.
Conservative Liberal or Liberal Conservative. S.A. Muromtsev at the Head of the First State Duma
Authors: Aronov Dmitry V. , Smirnov Ivan M.
Published: December 2020

In the article the authors examine the place and role of the prominent Russian lawyer and politician S.A. Muromtsev in the formation of Russian representative authority and parliamentary traditions. The authors analyze his role both in the theoretical preparation of the State Duma regulations project (“Nakaz”) and its practical realization in the procedures of the first Russian parliament.
Liberal-Conservative and Liberal Views on the Popular Representation in the Beginning of the 20th Century and Their Reflection in the Legislation of 1905–1906
Authors: Demin Vadim A.
Published: December 2020

The article is devoted to the study of the views of Russian liberals and liberal-conservatives on the representative authority in the beginning of the 20th century. It is shown that since the 70-ies of the 19th century all of them supported the transfer to representative authority. By the beginning of the 20th century even moderate liberals could not envisage further development of the country without such reforms. The revolution of 1905 intensified the activity of all social and political movements. Liberal conservatives supported the introduction of advisory representation that was to be elected by the democratized “Zemstva” and that should submit their opinions directly to the Emperor. The liberals pressed for the introduction of the parliament elected by universal, equal, direct and secret voting, that would issue laws, approve the budget and effect political control of the government. The development of political system reforms had bureaucratic and secret character. The demands of liberal society were taken into account only occasionally and only on minor issues. And it became the factor that intensified confrontation of the government and the educated society.
Women in Russian Parliament
Authors: Kryshtanovskaya Olga V.
Published: December 2020

The article devoted to the role of women in contemporary authority in general and in parliamentary institutions in particular. The author also offers a concise excursus in history noting the interesting opposition of feminist and “women” organizations from the point of view of their participation in power structures and their relevant goals, as well as their representation in the government bodies and structures. On the basis of large data arrays the author studies the dynamics of women participation in representative and legislative bodies of the state power starting with the USSR Supreme Soviet and to the State Duma of all convocations and the Council of the Federation from 1993 and until present time, including the representation of women in the governing structures of both chambers of the Federal Assembly.
Russian Parliamentarism: the Experience of the Institutional Creative Work
Authors: Makarenko Boris I.
Published: December 2020

The article consists of four case-studies, analyzing examples of building procedures and institutions of the parliament work. The first one deals with the experience of inter-faction agreement on principles and procedures of distribution of leading positions in the Duma among party factions, providing the actual power-sharing arrangement and respect of factions’ interests. The second describes the attempts o the “young parliamentarism” to solve the relevant problem of “party discipline”. It needs to be said that Duma has proved to be able to avoid excessive regulation of the issue, ensuring at the same time reasonably high discipline. The third case describes the difficult process of building an inter-factional coalition to ensure the passage of the politically and symbolically important law on private property of agricultural land. The fourth case examines the practice of coordination between the cabinet and Duma majority factions on important government-initiated bills prior to their formal introduction to Duma (“zero reading”). For three out of the four cases, related to different Duma convocations and different years, an updated analysis of the current status of the same practice or procedure is provided. The overall conclusion is that all the cases are characterized by instrumental and creative approach of Duma members to the problems, and though the outcome was never predetermined, effective and lasting solutions.
lmost all estimates of the figure of Alexander Solzhenitsyn are not related to literary criticism. Most studies evaluate his role, intentions and results. His figure is assessed in the context of the fate of the country, public perception and attitude to the country, which is Motherland for some, and mental and political enemy for the others. And for this purpose it is not even important who is right from the historical and political point of view. The point is who and how perceived the USSR and the entire Soviet project. Solzhenitsyn is seen as the enemy of the USSR and the Soviet project by those who popularized and helped him, and also according to his self-evaluation. Therefore, for those who identify themselves with the Soviet Union, its heritage and the entire Soviet project Solzhenitsyn represents the enemy and bearer of evil. For those who are hostile to the Soviet Union and the Soviet project, Solzhenitsyn is an ally in their struggle and bearer of good. Which of these parties is right is the issue of history and morality. 66% of Russian citizens support the first point of view, and the second point of view is supported by 25% of the population. Nowadays 88 % of Russian citizens know who Solzhenitsyn was. 31% consider him to be moral authority for them. 8% of the people believe that Solzhenitsyn presented true facts in his books.
Authors: Aksyuchits Victor V. 
Published: December 2020

In the article the author studies the formation process of Russian intelligentsia analyzing its «birth marks», such as nihilism, estrangement from native soil, West orientation, infatuation with radical political ideas, Russophobia. The author examines the causes of political radicalization of Russian intelligentsia that grew swiftly at the end of the 19th and beginning of the 20th centuries and played an important role in the Russian revolution of 1917.
The Ukrainian Question in the Work of Alexander Solzhenitsyn
Authors: Tsipko Alexander S.
Published: December 2020

The author of the article analyses the interpretation of the Ukrainian question in the work of A.I. Solzhenitsyn, highlighting his initially weak methodological viewpoints that, according to the author, do not comply with reality. The author believes that insufficient examination of archival documents, including those kept in the USA, – the country of temporary Solzhenitsyn’s emigration, – did not allow the thinker to recognize the real differences of the Ukrainian and Russian nations, existing in the past and projecting into the future. As the result Solzhenitsyn failed to comprehend and forecast the whole complex of the problems and the direction of the Russian-Ukrainian relations development that we can witness now.
Philosophical and Pedagogical Views of Yu. F. Samarin
Authors: Shaposhnikov Lev E.
Published: December 2020

The paper analyses the evolution of Yu. Samarin’s ideas from rationalism to “holistic knowledge”. Special attention is paid to the philosopher’s conceptualization of the key role of religion for a nation. The author also examines the scholar’s position concerning the promotion of patriotism as an important impetus for social development. Emphasis is made on analyzing the interaction of universal and national aspects in the educational process, as well as on the value of national identity in the field of humanities. The article also presents Yu. Samarin’s critical evaluation of the government educational policy and his suggestions on increasing its effectiveness. The author notes the relevance of Yu. Samarin’s views for the contemporary philosophical and educational context.
Attitude to the Categories of the Religious and the Secular in the Works of the Slavophiles (Kireevsky, Khomyakov, Samarin)
Authors: Shchipkov Vasiliy A.
Published: December 2020

The author analyses the main works of I.V. Kireevsky, A.S. Khomyakov and Yu. F. Samarin that touch upon the problems of religion and secularism (religious, secular). The author summarizes the common approaches of the three Slavophiles to this issue. The Slavophil methodology attributed the origins of the secularization process to the specifics of Western Christianity, which had finally formed at the time of the Great Schism. The Slavophiles paid attention to the religious nature of modern secular anti-religious ideologies, which though denying religion and their own religious origin, still could not offer any worthy alternative. All three philosophers defended Christian ontology, therefore they did not consider secularism in a humanistic and positivistic sense, as something which was opposite to religion or was an area beyond all religions.
“Russian Fichte”. Relevance of Yu.F. Samarin’s Philosophy of National Consciousness
Authors: Tyapin Igor N.
Published: December 2020

The significance of the national consciousness issues in Russian thought is still very high due to the persisting interconnection principles of the authority and society and strict separation of subject – object functions and roles. Underestimation of Yu.F. Samarin’s ideological heritage as an original interpreter of Fichte’s national spirit philosophy with reference to Russian reality calls for the reconstruction of his national consciousness concept that was formed in the process of the analysis of the social and political problems in Russia in the 19th century. The article demonstrates that Samarin criticized two false ways of the country development related to the “change of “sobornost” (collegiality)”, – cultivating of individualism (or individualistic Western nationalism) and total suppression of Russian people activity by the power while giving preferences to national minorities that resulted in “national spirit fade-out” and various defeats of the country, including military, – and so he came to the conclusion that it was possible to overcome national crisis through the efforts of national intelligentsia and reforms of the monarchy to pursue mass education and enlightment with the purpose of future moral and social ideal realization.
The Development and Validation of the Distance Doctoral Program Integration Scale
Authors: Holmes Joe L. , Rockinson-Szapkiw Amanda
Published: December 2020

Research indicates academic integration and social integration are predictors of doctoral student persistence at any program stage. However, researchers have not defined, operationalized, and measured academic or social integration consistently. Further, no instruments exist that specifically measure both academic and social integration of doctoral students in distance programs. The purpose of this research was to define distance doctoral program integration, and in turn, develop and analyze the structure, validity, and reliability of the Distance Doctoral Program Integration Scale. Instrument development followed a multi-step process including expert review, pilot test, and exploratory factor analysis. Instrument reliability was assessed using Cronbach’s alpha and test-retest. The results indicated a three-factor structure (i.e., faculty integration, student integration, and curriculum integration). The 32-item instrument is valid and reliable, measuring program integration of doctoral students studying at a distance.
A Statewide Study of Perceptions of Directors on the Availability of Online Student Support Services at Postsecondary Institutions
Authors: Brown Victoria S. , Strigle Josh , Toussaint Mario
Published: December 2020

As a state university system planned for growth in the availability of distance education degrees, the presidents and the provosts decided to include consideration for the availability of student support services. To ensure availability of student support services for online students, college and university systems in the state developed and implemented a self-reporting tool, the Online Student Support Scorecard to measure the availability of those services at both the college and the university levels. Although institutions were offering many of the services identified in the scorecard as essential, institutions were struggling to provide some of the services. Differences also were identified between the types of services available at the state college system compared with the university system.
Simulation of a waiting system
Authors: AMARIEI Olga-Ioana , HAMAT Codruța-Oana
Published: December 2020

This paper analyzes an existing production system in an industrial hall, consisting of 11 machines (service stations) and 13 intermediate stocks
(queues), where 4 types of parts are processed and assembled, with the aim of increasing production volume. The Queuing System Simulation module of the WinQSB software is used, which allows the simulation of waiting systems.
Three-Axis Level with WiFi Connection
Authors: MUSCAI Cristian-Mircea , MITULETU Ion-Cornel , MANESCU Tiberiu , PROTEA Liviu-Bogdan
Published: December 2020

The Three-Axial Level (TAL) device measures the angular inclination around the three axes of the orthogonal system. It consists of a triple-axis magnetometer sensor with I2C transmission and a NodeMCU V3 development board with WiFi module integrated. The device processes data from sensor, displays it on its screen and also transmits the angular values to various PADs (Portable Access Device). The experimental testing confirmed the initial expectation, showing the properly on-site operation of the designed device. This device is useful in the supervising process to avoid perturbing the worker that performs the leveling operation or when the working place is hard to reach.
Model of microprocessor centrifugal equipment for honey extraction
Authors: RĂDUCA Eugen , MOLNAR Mihaela , FARA Nicolae Titu
Published: December 2020

The paper presents a model of centrifugal equipment for extracting honey made around an ATmega 328 processor, with which the Arduino Uno module is equipped. The created model is functional, being tested, and the practical results obtained would allow the transition to prototype equipment. The created model is flexible, allowing to obtain flexible operating cycles, with variable speeds, soft settable, in both directions of rotation. The number of frames from which the bee honey can be extracted is variable depending on the juicer itself, which is driven by the motor.
Technical performance analysis of a 40 kW photovoltaic installation
Authors: SPUNEI Elisabeta , PIROI Ion , PIROI Florina
Published: December 2020

To reduce the consumption of classically produced electric energy, which is an important green gas pollution factor, various renewable energy sources are now implemented on larger and larger scale. Both industrial and household consumers make use of such renewable energy sources. This work presents the characteristics and performance of a 40 kW photovoltaic installation mounted on the roof of an industrial production hall. The design and the implementation of the photovoltaic installation allows it to function while connected to the local power grid. On-site measurements have shown that the installation ensures symmetric voltages and currents, functioning at the planned parameters.
MODERN EVENING SCHOOL AS AN INNOVATIVE INFORMAL EDUCATIONAL ESTABLISHMENT
Authors: ZAKOMIRNI IGOR
Published: December 2020

The author analyses the features of the popular forms of education for adults. He reveals the role of information and communication technologies in non-formal educational settings and also the role of teachers of evening schools. He focuses on information and communication competencies associated with effective implementation of innovative technologies in educational process.
SOCIAL HERITAGE OF ORPHAN CARE
Authors: ANTONYAN MIRA
Published: December 2020

Social expertise of the Armenian Nation of the orphan care mostly depends on the emotional perception of genocide orphans struggles and the adequate behaviour towards them. The analysis of social expertise in orphan care includes three main phases: before genocide, after genocide, and during the Soviet era. Examining the rich heritage of social expertise during those phases, the article addresses its effects on modern, post-Soviet perceptions of orphan care in the context of social work. The article justifies the need to modernize state and charity approaches to current perceptions of the problems of social orphanhood, and children deprived of parental care.
SOCIO-PSYCHOLOGICAL CHARACTERISTICS OF ADULT DEVELOPMENT AND LEARNING
Authors: ZINCHENKO SVETLANA , KOTIRLO TAMARA
Published: December 2020

The article investigates the problems of adult education, particularly social-psychological characteristics of adult development and learning are analyzed. The author gives the definition of the institutional peculiarities of adult education. As it is stated in the article, adult learning is a firm basis of his/her psychological development. Life-long education is a guarantee of the individual’s cognitive development.
PROCESSES OF SEXUAL PUBERTY AND DESTRUCTIVE MANIFESTATION OF SEXUAL IDENTIFICATION IN TEENAGER PERIOD
Authors: KHACHATRYAN LILIT
Published: December 2020

The importance of sexual puberty processes for formatting sexual self conciousness and sexual behaviour are discussed in the article. The peculiarities of distructive manifistation of sexual idendification during puberty period in insufficient gender socialization conditions are presented by the author.