bluuebunny/crossref_metadata_2025 huggingface dataset:
Pathological investigation and viral antigen distribution of postweaning multisystemic wasting syndrome in association with porcine parvovirus infection of pigs in Kerala, Southern India
Authors: Sairam R. , Krishna B. Dhanush , Krithiga K. , Priya P.M. , Anoopraj R. , Ravishankar Chintu , Sajitha I.S.
Published: January 2024

Postweaning multisystemic wasting syndrome (PMWS) is one of the important emerging porcine circoviral associated disease (PCVAD) causing immense economic losses throughout the world producing mortality and morbidity mainly in post-weaned pigs. During the period from 2018-2019, a total of 50 pig carcasses from different parts of Kerala were screened for concurrent infections of porcine parvovirus (PPV) and porcine circovirus type 2 (PCV2), followed by the establishment of PMWS. All the samples were subjected to polymerase chain reaction (PCR) initially followed by histopathology and immunohistochemistry (IHC). Phylogenetic analysis was performed for PPV using non-structural gene -1(NS1). The result of the molecular screening using polymerase chain reaction revealed only one sample to be positive for both PCV2 and PPV. The gross lesions noted were the non-collapsed voluminous lungs, necrotising lymphadenitis, interstitial nephritis, splenomegaly and fibrinous pericarditis. Histopathological examination revealed mild interstitial pneumonia, lymphoid depletion in periarteriolar lymphoid sheaths of spleen with focal areas of granulomatous inflammation, depletion of the germinal centre of the follicles in the lymph nodes, non-suppurative myocarditis and interstitial nephritis. Further, immunohistochemistry demonstrated PCV2 and PPV antigens in the affected tissues. Based on the clinical signs, histopathological lesions and immunohistochemical demonstration of PCV2 antigen, the case was confirmed as PMWS in association with PPV. This report of PMWS in association with PPV confirms, probably for the first time in the Kerala state of India.
Radiographic evaluation and comparative efficacy assessment of stanozolol and prednisolone acetate in canine tracheal collapse
Authors: Shamly T.M. , Ajithkumar S. , Unny N. Madhavan , David Vinu. P. , Raji K.
Published: January 2024

Canine tracheal collapse is a progressive, enduring and fatal respiratory insufficiency syndrome of dogs, which causes agony to the pet and pet parents alike. The disease is characterised by cartilage flaccidity and flattening of the tracheal rings and causes paroxysmal ‘goose honking cough’. In this study, efficacy of stanozolol and prednisolone acetate in healing tracheal collapse was studied, which was assessed by radiographic findings. It was found that stanozolol at a dose of 0.15 mg/kg twice daily for 30 days followed by a tapering dose was more effective than prednisolone acetate in the medical management of tracheal collapse. Even though, there are reports on single dog breeds with tracheal collapse, studies on both brachycephalic and normocephalic dog breeds were not traceable. Moreover, no previous study has evaluated the comparative efficacy assessment of stanozolol and prednisolone acetate in canine tracheal collapse.
Development and Assessment of Awareness Module on ‘Antimicrobial Resistance and its Prevention’ for School Students in Punjab, India
Authors: Dhaka P. , Bedi J.S. , Sharan M. , Iqbal S. , Gill J.P.S.
Published: January 2024

Antimicrobial resistance (AMR) is one of the pressing public health issues. Sharing information on AMR with school students will educate and inspire them to act as community ambassadors. The present study was carried out in the form of capacity-building workshops among school children of the Ludhiana district of Punjab, India. Three workshops were organized in three different higher secondary schools for 11th and 12th standard students (medical stream). Each workshop session included an interactive teaching module on basic microbiology, AMR, factors involved in AMR emergence, ‘One Health’ approach to address AMR, and how we can contribute to the community. The learning outcomes were evaluated based on pre and postworkshop assessment questionnaires. A total of 138 students participated in the workshops with an average duration of around 3.5 hours. Among all the students, 68.84% were not aware of the meaning of ‘antibiotic resistance’ and 78.26% believed that antibiotics can cure all coughs and colds. Furthermore, 82.61% of students never heard the term ‘superbugs’ and 71.74% were not able to identify the factors for AMR emergence. The success of teaching workshops was assessed by significant improvement in the correct responses during the post-workshop quiz, where the median post-workshop score (i.e., 14/15) was significantly improved as compared to the pre-workshop score (i.e., 08/15). We propose that the concepts of AMR must be included in school curricula so that young students can be ‘superheroes’ in bringing about desired changes in the community.
Effect of supplementation of polyherbal feed additives on growth performance and nutrient digestibility in crossbred (LWY X Desi) finisher pigs
Authors: Lavanya M. , Babu D. Suresh , Suresh J. , Punyakumari B. , Reddy G.V. Bhaskar , Kamalnathreddy M.
Published: January 2024

The present experimental trial was conducted to evaluate the effect of polyherbal feed additives on the growth performance and nutrient utilisation of pigs during the finisher phase. Five groups of six pigs each with body weight of 35 kg were fed a common concentrate feed mixture (CFM) without any herbal feed supplements (T0), CFM with Restobal @ 15ml/day/animal mixed with feed once in every three days (T1), CFM with Stresomix @ 250g/tonne (T2), CFM with Ruchamax (T3) and Nbiotic (T4) each @ 500g/tonne, respectively up to attaining of live weight about 70 kg. During the experiment, the daily feed intake as well as weekly body weight was recorded. A digestion trial of seven-day duration was conducted at the end of feeding trial. Addition of herbal feed supplements did not significantly (p>0.05) influence the initial, final body weights and feed consumption (kg/day) of pigs. Among all experimental groups of pigs, pigs fed with Stresomix (T2) attained 70 kg from 35 kg body weight in 75 days, followed by T3 and T4 groups in 79 days and T1 group in 82 days and T0 groups in 90 days. Significant (p<0.05) increase in CP digestibility was found in pigs fed with herbal feed supplements (T1 to T4) than control diet (T0) and there was no significant (p>0.05) difference in digestibility of other nutrients.It was observed that including polyherbal preparations at an acceptable dose with concentrate feed will improve pig performance and nutrient digestibility while having no negative impact on their health.
Ethnozoological study of animal based medicines used by traditional healers from south eastern area of Golaghat district, Assam
Authors: Saikia Gitashri , N.L. Raju
Published: January 2024

Animals have played an important role in human life from ancient times. The knowledge on the use of many animals and their by-products in traditional medicines by various ethnic communities is generally passed verbally from one generation to the next. The present study was carried out on ethnozoological survey of animal based medicines used by traditional healers from south eastern area of Golaghat District, Assam. A total six communities viz., Koch, Kalita, Chutia, Ahom, Nath and Mising have been chosen based on semi-structured questionnaire through interactive personal interview and group discussion on the use of traditional animal based medicines by these local people for the treatment of various diseases. During the survey around 200 respondents were interviewed including 30 traditional practitioners. A total 40 distinct species were identified along with the formulations they utilize to cure various ailments. The study showed that the use of traditional medicines are still popular in rural areas which may depict a scenario of their strong belief on their formulations or may be due to inaccessibility of health care facilities in availing modern medicines. It is evident that the ethnozoological information regarding the therapeutic uses of different animals in traditional medicine is fading and there is an urgent need for its documentation before much of it is completely lost..
Molecular docking approach to identify potential anticancer agents from Sida cordifolia and Eupatorium triplinervis
Authors: Menon K. Priyanka , Kariyil Bibu John , Sivapriya S. Aparna , Nair S. Arundhathy
Published: January 2024

Sida cordifolia and Eupatorium triplinervis have been used traditionally for treatment of various ailments. An in-silico study was carried out to identify the interaction between the selected phytocompounds with B-cell lymphoma 2 (Bcl2). The crystal structure of the Bcl2 protein (PDB Id: 4LXD) of Homo sapiens was used as the receptor. The docking was done with AutoDock V 4.0 using twenty-one ligands from both plants and the binding energy was assessed. The binding energy of various phytocompounds were observed to range from -2.74 Kcal/mol to -7.47 Kcal/mol. The standard compound doxorubicin showed a binding energy of -6.95 Kcal/mol. The compound stigmasterol and sitosterol showed binding energies of -7.15 and -7.47 Kcal/mol respectively. Molecular binding of the compounds was strengthened by hydrogen bonds and hydrophobic interactions. Hence the plant extracts can be used to separate promising lead compounds with anticancer activity.
Assessment of acute kidney injury in dogs suffering from babesiosis and leptospirosis
Authors: Idrees Asma , Deepa P.M. , Vinodkumar K. , Rathish R. L. , Pradeep M.
Published: January 2024

Acute kidney injury (AKI) is a serious complication of infectious diseases like babesiosis and leptospirosis in dogs. Both the diseases show similar clinical manifestations, due to which timely differential diagnosis often gets delayed. The present study focused on diagnosis of major infectious agents causing AKI and its grading in dogs. Peripheral blood smear examination and PCR were used for the diagnosis of babesiosis. Leptospirosis was screened using PCR and MAT and was later confirmed by MAT on paired sera sample. Diagnosis of AKI was made based on the increase in serum creatinine levels ≥0.3 mg/dL within 48 h of presentation. Staging of animals was carried out as per International Renal Interest Society (IRIS) guidelines. All the dogs with confirmed leptospirosis and 15 per cent of dogs with babesiosis were diagnosed with AKI. The timely diagnosis of AKI in dogs during their initial stages helps to regain normal renal function within short-term treatment itself.
Metabolic and immune status of pre-weaning crossbred calves reared on different dietary regimes in Kerala
Authors: Sasidharan Manju , Kannan A. , Shyama K. , Raji K. , Sunanda C. , Harikumar S. , Mathew Joseph
Published: January 2024

Seventy two new born crossbred calves were selected and grouped in three dietary treatments-C, T1 and T2. Calves in the group T1 were fed ad libitum milk twice daily for one hour along with calf starter and green fodder. The T2 group were fed on the dietary protocol as T1 but was fed calf starter supplemented with essential oils. The dietary treatment of control group (C) was as per the Package of Practices Recommendations, KVASU. Blood samples were collected from the calves at the time of birth, second day and monthly intervals for up to three months for biochemical analysis. The plasma glucose concentrations of calves in dietary treatments C, T1 and T2 after one month were 5.69±0.166, 6.26±0.174 and 6.15±0.166 mM respectively. The glucose levels of calves in dietary treatments of C, T1 and T2 at three months were 4.22±0.062, 4.50±0.061 and 4.33±0.063, respectively and differed significantly (p<0.01) between C and T1. The serum concentration of Betahydroxy butyric acid (BHBA) for dietary treatments C, T1 and T2 increased with age and reached 0.418±0.025, 0.403±0.026 and 0.410±0.025 mM respectively and did not differ significantly between treatments. Significantly higher (P<0.05) serum cholesterol concentration of 2.82±0.090 and 2.86 ± 0.086 mM were recorded in calves in T1 and T2, respectively. Serum concentration of triglycerides, total protein and albumin were similar in all treatment groups. Lower BUN values of 8.96±0.64 and 8.89±0.64 mM were seen in T1 and T2, respectively while C group had serum BUN concentration of 10.33±0.63 mM. Increased levels of serum BHBA indicated rumen development where there is a shift in the precursor of energy from glucose to volatile fatty acids. Ad libitum colostrum feeding resulted in significantly higher (P<0.001) level of IgG from the second day improving the immune status of new-born calves.
THE ORETICAL AND PRACTICAL BASES OF SOIL-BASED WASTEWATER PRETREATMENT
Authors:   Korkyt Ata Kyzylorda University, Republic of Kazakhstan, Shomantayev A.A. , Otarbayev B.S. ,   Korkyt Ata Kyzylorda University, Republic of Kazakhstan, Daldabayeva G.T. ,   Korkyt Ata Kyzylorda University, Republic of Kazakhstan, Olzhabayeva A.O. ,   Korkyt Ata Kyzylorda University, Republic of Kazakhstan
Published: January 2024

In recent years, increasing anthropogenic loads on the environment, especially pollution of surface water by return water has complicated the ecological situation in the region of the Kazakhstan part of the Aral Sea region, worsened the sanitary conditions of life and health of people. A complicated situation has developed with wastewater separation of the cities of the Republic of Kazakhstan. In the next 20 years, when volumes of sewage will increase 1.5-2.0 times, industrial methods of treatment can not provide protection of watercourses, because of the large amount of residual pollutants discharged even with treated effluents. In this regard, the study of main sources of surface water pollutants and development of scientifically-based principles of agricultural use of return water (sewage and collector-drainage water) in the lower reaches of the Syrdarya River acquire special urgency. This approach solves not only issues of water bodies protection from pollutants, but also irrigation water saving, providing irrigation fields with elements of mineral fertilizers, increasing soil fertility and yield of agricultural and forestry crops. There are many attempts in domestic and foreign science to create a scientific concept of rational and reasonable use of wastewater and collector-drainage water (CDW) in agriculture and forestry. However, it is not possible to transfer in conditions of Syrdarya river lower reaches because of natural-climatic peculiarities of the region
Three-dimensional characterization of zygomatic arch morphology and its relation to the articular eminence in a Brazilian population
Authors:   Department of Biosciences, Anatomy Division, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil, Watanabe Luciane N.O. , Rossi Ana C. ,   Department of Biosciences, Anatomy Division, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil, Smith Amanda L. ,   Pacific Northwest University of Health Sciences, Yakima, Washington, USA, Ferreira-Pileggi Beatriz C. ,   Department of Biosciences, Anatomy Division, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil, Daruge Júnior Eduardo ,   Department of Health Science and Pediatric Dentistry, Forensic Dentistry Division, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil, Prado Felippe B. ,   Department of Biosciences, Anatomy Division, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil, Freire Alexandre R. ,   Department of Biosciences, Anatomy Division, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil
Published: January 2024

Zygomatic arch and articular eminence are structures from the human skull involved in jaw muscle activity. The aim of the study was to evaluate three-dimensional morphological patterns of the zygomatic arch and its relationships with articular eminence in a Brazilian population. 122 computed tomography scans of human skulls were evaluated. The Mimics 18.0 software (Materialise, NV, Belgium) was used to perform segmentation of images from CT scans. 3D reconstructions of CT scans were imported into Rhinoceros 5.0 software (McNeel & Associates, Seattle, USA), in which linear measurements (mm) were obtained. Statistical analysis was performed in GraphPAD Prism v.8 (San Diego, CA, USA). The normality of the sample was checked by Shapiro-Wilks and significance level of 5% was considered. Based on cross-sectional area classification, out of 116 male zygomatic arches the incidence was 59% of type elliptical (E) and 41% of type blade-like (Bl). Out of 102 female zygomatic arches the incidence was 38% of type E and 62% of type Bl. There was no incidence of type cylindrical (C). Based on the classification proposed in the present study, the incidence for males was 58% of type parentheses (P), 38% of type bracket (B) and 4% of type M-shaped (M); and the incidence for females was 33% (type P), 66% (type B) and 1% (type M). The elliptical and convex body of the zygomatic arch prevailed in males and the blade-like and straight body of the zygomatic arch prevailed in females. There is no relationship between zygomatic arch type and zygomatic arch and articular eminence distances.
Ossification pursue of the lower ends of radius and ulna and age determination in a sample of Egyptian population between 12 and 19 years
Authors:   Dept. of Anatomy and Embryology, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, AlDomairy Ahmed F. , Kotb Ashraf ,   Dept. of Physiology, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, Eldesouky Manar A. ,   Lecturer of Pediatrics, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, Yehia Mohamed A. ,   Lecturer of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, Eisa Yasmine H. ,   Lecturer of Public Health and Preventive Medicine, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, Farag Ahmed T. ,   Lecturer of Orthopedic Surgery, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, Assem Mahmoud M. ,   Lecturer of Radiology, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt, Elsabban Radwa M. ,   Lecturer of Anatomy and Embryology, Faculty of Medicine, October 6 University, 6th of October City, Giza, Egypt
Published: January 2024

The epiphyseal plates of cartilage of ulna and radius is responsible for bone elongation, the fusion of their distal ends and bodies is used for age estimation. Variation exists due to many factors including ethnicity; accordingly, it is important to create a national profile for age determination using an affordable easy method. The aim of the work was to follow up the ossification of the lower end of the radius and the ulna in the Egyptian population between 12-19 years using X-ray, validating the use of Greulich and Pyle atlas. 197 subjects (103 males and 94 females) aged between 12-19 years were included. Skeletal age was determined using a plain X-ray on the lower end of the radius and the ulna comparing it to Greulich and Pyle’s atlas, and also to chronological age. In males, the mean of chronological age, skeletal age, and the difference between them were 15.35, 15.53 and +0.18 years respectively. In females, the ages were 14.77, 14.92 and +0.15. There was high correlation in all age groups. Examination of the lower end of the radius and the ulna is a suitable method for age detection in Egyptians between the ages of 12-19 years old.
Characterization of the histological changes in ovaries of Goto-Kakizaki diabetic rats
Authors:   Don Benito Oeste Primary Care Center, Extremadura Health Service, Badajoz, Spain. Department of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, Cadiz, Spain, Montero-Peña Cristian , Morales-De Pando José M. ,   Puerta del Mar Hospital, Andalusian Health Service, Cadiz, Spain, Díaz-Gómez Alfredo ,   Department of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, Cadiz, Spain, González-Medina Gloria ,   Faculty of Nursing and Physiotherapy. University of Cadiz, Cádiz, Spain, Ribelles-García Antonio J. ,   Department of Human Anatomy and Embryology, Faculty of Medicine, University of Cadiz, Cadiz, Spain, Pérez-Arana Gonzalo ,   Biomedical Science Research and Innovation Institute (INIBICA), University of Cadiz. Department of Human Anatomy and Embryology, Faculty of Medicine. Cadiz, Spain, Prada-Oliveira José A. ,   Biomedical Science Research and Innovation Institute (INIBICA), University of Cadiz. Department of Human Anatomy and Embryology, Faculty of Medicine. Cadiz, Spain
Published: January 2024

Goto-Kakizaki (GK) rats are a useful animal model for studying type 2 diabetes mellitus (T2DM). However, this strain of rats exhibits poor fertility, so it is difficult to expand colonies. Based on previous studies, it was hypothesized that alterations in the oestrous cycle of diabetic rats are related to ovarian histology. The aim of this study was to determine the histology of the ovaries of diabetic rats compared to nondiabetic rats to understand the poor fertility of this strain of diabetic rats. An experimental study was thus conducted. Eight GK rats and eight Wistar rats were utilized. The rats were age-adjusted into two groups called “young rats” and “mature rats” at two and fourteen months of age, respectively. After sacrificing the rats, the ovaries were dissected and processed by fixation and paraffin embedding to perform the histological study. The results included the number of corpora lutea and the percentage of follicular fraction in each ovary, as well as qualitative data such as the presence of follicles in different stages of development. Our findings revealed differences between GK and Wistar rats. The ovarian histological findings were related to the presence of T2DM, polycystic ovary syndrome and poor fertility in female GK rats; the link between these pathologies is insulin resistance. Future lines of investigation into metabolic treatment, which may help improve insulin resistance, could also benefit the previously described pathologies in female GK rats.
καὶ τὸν βίον τὸν ὑμέτερον αὐτῶν ἀσφαλέστερον καταστήσετε. Malhechores y policía en la Atenas clásica
Authors: Antolín García Aurora
Published: January 2024

Un tema recurrente en los estudios clásicos ha sido la consideración de la violencia en la Antigua Grecia y, a partir de ahí y con el auge de los estudios de criminalística, se han dedicado también numerosos trabajos a la criminalidad en el mundo antiguo. No obstante, se debe ser cauto a la hora de aplicar nuestros conceptos modernos sobre el crimen y su represión a las sociedades antiguas. Los niveles de criminalidad en la Atenas clásica parecen no haber sido muy elevados, y tal vez por ese motivo los instrumentos del estado para contenerlos no estuvieran muy desarrollados. No sería correcto, sin embargo, dejarnos llevar por una perspectiva contemporánea y afirmar que esos instrumentos, a los que en el mundo moderno definiríamos como policía, no existieran en absoluto. La Atenas democrática contaba con toda una estructura de magistrados e instituciones que se encargaban de hacer cumplir las leyes, aunque la iniciativa privada desempeñara también un papel notable.
Una revisión del Arte Rupestre Atlántico desde la arqueología de género
Authors: Pereira-Martínez Xurxo , Prieto Martínez M. Pilar , Méndez-Quintas Eduardo
Published: January 2024

El objetivo de este trabajo es evidenciar la necesidad de vincular la arqueología de género y feminista a las investigaciones sobre arte rupestre del noroeste peninsular. Para ello, realizamos en primer lugar un repaso por la historia de las investigaciones del Arte Rupestre Atlántico (ARA), evidenciando el discurso androcéntrico presente en muchos de los trabajos realizados hasta la fecha; y, por otra parte, exponemos los resultados del análisis de figuras naturalistas (antropomorfos y animales) presentes en paneles del suroeste gallego y norte portugués. Precisamente, este caso de estudio nos ha servido para ilustrar que la sobrerrepresentación del género masculino en los trabajos sobre ARA no obedecía a razones empíricas, sino a ciertos apriorismos insertos en las investigaciones, predominando la indeterminación a la hora de representar este tipo de motivos en el noroeste ibérico.
Las producciones de tradición Cogotas I en el territorio argárico: El caso de Peñalosa (Baños de la Encina, Jaén).
Authors: Vico Triguero Laura , Contreras Cortés Francisco , Cámara Juan Antonio , Martín Peinado Francisco
Published: January 2024

Se presentan los resultados obtenidos del estudio arqueométrico de las cerámicas con decoración de tradición Cogotas I del poblado argárico de Peñalosa (Baños de la Encina, Jaén). El empleo de técnicas procedentes de las Ciencias de la Tierra (petrografía mediante lámina delgada, difracción de rayos X y microscopio electrónico de barrido) han permitido comparar las producciones típicas argáricas del yacimiento de Peñalosa con las cerámicas de tradición Cogotas I, con lo cual se ha podido definir distintos grupos de manufactura en este yacimiento. Los resultados obtenidos han permitido definir una serie de “Grupos de Manufactura” que han mostrado unas características en cuanto a fabricación y composición que evidencian una similitud en la producción de las cerámicas de tradición Cogotas I y las consideradas como típicas argáricas. Por lo tanto, se puede afirmar la existencia de producciones de tradición Cogotas I en el Alto Guadalquivir en fechas tempranas (1700 a.C.), más relacionadas con las de la Meseta, lo que indica un intercambio de ideas, personas, materiales, etc. que favorecieron la adopción de este tipo de producciones en contextos argáricos. Esto plantea la posibilidad de una vía de inserción de los pueblos meseteños a través de las cuencas del Tajo y del Duero, donde las relaciones de intercambio de minerales u objetos metálicos pudieron jugar un papel importante en este contacto.
Valorisation of pre and protohistoric twin vessels found in the Portuguese territory.
Authors: Vilaça Raquel , Amor Santos Ana
Published: January 2024

This text examines twin pottery forms dating from the Bronze and Iron Ages found in the current Portuguese territory. The published data is gathered and explored further whilst presenting five unpublished specimens, as well as others nearly forgotten until now. This integrative approach allows for a thorough inventory of this pottery universe, accompanied by the elaboration of a typology proposal, although subject to the sample’s high level of fragmentation. The analysis of specimens and the valorisation of their contexts (mainly settlements, except a cave of ritual nature) is combined with the scenery of twin vessels in the remaining Iberian space and even beyond it, commenting on some of the interpretative challenges around these peculiar pottery forms, namely in the matter of function and semantics.
Los “colgantes-amuleto” de oro castreños en forma de piel extendida: aportaciones para su estudio
Authors: García-Vuelta Oscar
Published: January 2024

se presenta una revisión actualizada de un grupo de cinco piezas de oro con estructura laminar y decoración de filigrana y granulado supuestamente procedentes de Asturias, con paralelos en dos ejemplares de la provincia de Palencia. Se han valorado como amuletos y por el perímetro de sus cuerpos han recibido denominaciones como en “reloj de arena”, o en “piel extendida”, entre otras. La falta de información contextual y de estudios actualizados han limitado su investigación, permaneciendo en discusión cuestiones como su origen, su cronología o su posible significado. El estudio de la información documental actualmente disponible y la revisión tecnológica de los objetos aportan una nueva base de datos para su interpretación. Estos datos permiten sugerir su relación con áreas específicas de producción probablemente localizadas en el área castreña, que reflejan tanto la influencia mediterránea en esa orfebrería como sus relaciones con la orfebrería del área celtibérica.
Study of the Properties of Antifriction Rings Under Severe Plastic Deformation
Authors:   Rudny Industrial Institute, Kazakhstan, Rudny, 50 years of October Street, 38,, VOLOKITINA Irina , VOLOKITIN Andrey ,   NPJSC «Karaganda Industrial University», Kazakhstan, Temirtau, Republic Avenue, 30,
Published: January 2024

A study was conducted of the properties of brass blanks for antifriction rings under severe plastic deformation by high pressure torsion. The evolution of microstructure and mechanical properties of deformed blanks after 6 cycles of deformation by high-pressure torsion at 500°C were studied. All metallographic studies were carried out using modern methods: transmission electron microscopy (TEM) and analysis of patterns of back-reflected electron diffraction (EBSD). As a result of deformation an ultrafine grain structure with the presence of a large number of large-angle boundaries was obtained. Strength properties of brass increased in comparison with an initial condition almost in 3 times, microhardness also increased in 3 times, i. e. increased from 820 MPa in initial condition up to 2115 MPa after deformation. Thus the greatest gain of strength properties falls at the first two cycles of deformation
Context matters in history textbook studies: A call to address the socio-political landscape of textbook production
Authors:   University of British Columbia, Canada, Clark Penney , Llewellyn Kristina ,   University of Waterloo, Canada, Capó García Rafael ,   University of British Columbia, Canada, Clifford Sarah
Published: January 2024

History textbooks are a tool of nation-building and often the only account of particular events, people and issues to which students will be exposed. This is one reason why it is important to examine, not only their content, but the context of their production. Research attention needs to be directed not only at disentangling the logics of textbook content, a purpose that dominates the field, but also at the social and political contexts of their development, including their production (publishing and authorship) and the processes by which they receive official approval. This work analyzed 100 history textbook studies in order to identify current trends in textbook research. This article focuses on one of the four major findings of the study: textbook studies often focus on the content of the textbook in isolation from the socio-political landscape of textbook production. The socio-political landscape refers, but is not limited to, the influence of local and geopolitics; the influence of the state, evident primarily in the official approval processes employed by governments; the economic dimension and publication parameters; and authorship factors. Among the relatively few studies that address the socio-political landscape, the authors often employ a historiographical or comparative perspective. The historiographical perspective, which is dominant, offers an analysis of textbooks over time in order to reveal both continuities and changes in the historical narratives produced by their authors. One example is a study by Yeow Tong Chia (2013), who examines conceptions of ‘Chineseness’ and China in Ontario high school history curricula and textbooks in the post Second World War to the 1980s period. More broadly, the paper locates the Ontario textbooks in the international context of the western-centric perspectives that were prevalent following the Second World War. The comparative perspective analyzes textbooks across regions in one historical moment. For example, Jason Nicholls (2006) addresses the role of national contexts in determining how the Second World War is portrayed in textbooks found in the United States, Italy, Sweden, Japan, and England.
Adaptación y validación de la Patient Health Questionnaire for Depression and Anxiety (PHQ-4) en una muestra de quechua hablantes peruanos
Authors: Carranza Esteban Renzo Felipe , Mamani-Benito Oscar , Cjuno Julio , Tito-Betancur Madona , Caycho-Rodríguez Tomás , Vilca Lindsey W. , Torales Julio , Barrios Iván
Published: January 2024

Introducción: El Patient Health Questionnaire for Depression and Anxiety (PHQ-4) es una medida de autoinforme ultrabreve de síntomas depresivos y ansiosos. El PHQ-4 no ha sido adaptado ni validado en la población quechua hablante. Objetivo: Este estudio tuvo como objetivo adaptar y validar el PHQ-4 en una muestra de población peruana quechua hablante en su variante Collao de Puno-Perú. Metodología: Participaron 221 personas hablantes de quechua variante collao (promedio de edad de 31,2 años, SD = 11,7, 47,1 % hombres y 52,9 % mujeres). Se evaluó la evidencia de validez basada en la estructura interna, mediante el análisis factorial confirmatorio (CFA), la fiabilidad con el método de consistencia interna y las características de dificultad y discriminación de los ítems en base a la Teoría de Respuesta al Ítem (IRT).  Resultados: Los resultados indicaron que todos los ítems del PHQ-4 son relevantes, coherentes y claros para representar adecuadamente los síntomas de ansiedad y depresión. El resultado del AFC apoyó un modelo unifactorial, donde los ítems de ansiedad y depresión conforman una sola variable latente con una fiabilidad alta. Todos los ítems del PHQ-4 presentas buenos parámetros de discriminación y los parámetros de dificultad indican que los ítems son comparativamente difíciles. Por lo tanto, se necesita una mayor presencia del rasgo latente (ansiedad y depresión) para responder las categorías de respuesta más altas.Discusión: En conclusión, la PHQ-4 presentó buenas propiedades psicométricas como una medida de detección primaria rápida, confiable y válida para personas quechuahablantes que necesitan una evaluación profunda, monitoreo de los síntomas para diagnóstico y tratamiento para la ansiedad o depresión.
A Study of Chowon (蕉園) Kim Seok-shin (金碩臣)'s Life and Paintings: Focusing on Real Landscape Paintings of Suburbs of Old Seoul
Authors:   The Paek-San Society, Im Mihyun
Published: January 2024

Kim Seok-shin (⾦碩⾂, 1958~?) was born into a major family of painters during the Late Joseon Dynasty, Kaesung Kim family (開城⾦⽒), and was a painter of the court under the reign of Jeongjo and Sunjo. Although he was overshadowed by the fame of his uncle Kim Eung-hwan(⾦應煥, 1742?~1789) and brother Kim Deuk-shin (⾦得⾂, 1754~1822), he indeed was a capable painter with substantial talent in landscape painting.
There are five pieces of true-view landscape paintings by Kim Seok-shin depicting the real landscape of suburbs of Seoul. Of these, Dobongdo (道峰圖), as its title suggests, appears to have been produced by Kim Deuk-shin upon the request of Dobongsan sightseeing by Criminal Judge Lee Jae-hak(李在學, 1745~1806) and Left Uijeong Seo Yong-bo(徐⿓輔, 1757~1824) in 1805 (Sunjo Year 5). Other paintings are also determined to have been painted at the same time as they depict scenic places around Seoul and the sizes and strokes are all similar. These paintings by Kim Seok-shin express popular spots of the Han River as realistically as possible and in an original way under direct and indirect influence by senior painters including Jung Seon (鄭敾, 1676~1759), Sim Sa-jung (沈師正, 1707~1769), Kim Eung-hwan, and Kim Hong-do (⾦弘道, 1745~1806?). Especially, apart from Kim Deuk-shin who was greatly influenced by Kim Hong-do, directly succeeding Kim Eung-hwan’s style, who had been influenced by Jung Seon and Sim Sa-jung, his style is more apparent in demonstrating Kaesung Kim family’s style, as well as the variety and process of change of landscape paintings during the Late Joseon Dynasty. Furthermore, his descendants continued to work as painters of the court as family business, lading to a conclusion that his painting style may have provided certain impact on establishing Kaesung Kim family’s style. In conclusion, Kim Seok-shin appears to have played a pivotal role in establishing Kaesung Kim family as a prestigious painters family, and substantially impacted the court painting style during the Postand Late Joseon Dynasty.
Preservation and Utilization of the Military Garrison in Jeongjoksanseong Fortress as a Complex Cultural Heritage
Authors:   The Paek-San Society, An Daiwhan
Published: January 2024

Previously, there was a limit to creating and disseminating value because the focus was on the intrinsic and fixed value of a single cultural heritage. However, efforts to create and increase the value of cultural heritage are currently being made in various ways. In this study, we attempted to present the concept of complex cultural heritage as a heritage whose value must be understood, including its relationships with surrounding things. Therefore, it is believed that the value of complex cultural heritage can be created, accumulated, and increased. And it showed that values can be passed down through education. In this study, an attempt was made to present the concept of complex cultural heritage and apply it to the Military Garrison in Jeongjoksanseong Fortress, Ganghwa. The Military Garrison in Jeongjoksanseong Fortress, of course, has intrinsic and fixed value as an individual cultural heritage. In addition, it was discovered that the Military Garrison in Jeongjoksanseong Fortress is a complex cultural heritage that can create value through relationships with various types of tangible and intangible cultural heritage around it. Furthermore, it was suggested that it should be viewed from the perspective of a complex cultural heritage that not only has value as a local culture but also serves as part of the unique defence system of Ganghwa Island as a whole. It was believed that the Military Garrison in Jeongjoksanseong Fortress had a high possibility of increasing its value from the perspective of this complex cultural heritage. Through the concept of complex cultural heritage applied to the Military Garrison in Jeongjoksanseong Fortress, we sought to provide a basis for viewing cultural heritage from a more diverse and broad perspective in the future.
Birmingham hip resurfacing: a systematic review of outcomes at minimum 10-years follow-up
Authors: DAVEY M.S. , MOHAN K , GAVIN E , POWER F.R. , CURTIN W , KAAR K , MURPHY C.G.
Published: January 2024

Although controversy surrounding the use of metal-on-metal (MoM) arthroplasty implants continues to exist, satisfactory clinical and radiological outcomes have been reported following Birmingham Hip Resurfacing (BHR) at long-term follow-up, leading to an Orthopaedic Data Evaluation Panel (ODEP) rating of 13A. The purpose of this study was to systematically review the literature to evaluate the functional outcomes, radiological outcomes and revision rates following BHR at a minimum of 10 years follow-up. Using the PRISMA guidelines, two independent reviewers performed a literature search using Pubmed, Embase and Scopus databases. Only studies reporting on outcomes of BHR with a minimum of 10 years’ follow-up were considered for inclusion. A total of 12 studies including 7132 hips (64.8% males), with mean follow-up of 11.5 years (10-15.3), met our inclusion criteria. Of included patients, 94.3% of patient underwent BHR for osteoarthritis at a mean age was 52.0 years (48-52). At final follow-up, 96% of patients reported being satisfied with their BHR, with mean Harris Hip Scores of 93.6 and Oxford Hip Scores of 16.5. Rates of radiological femoral neck narrowing of greater than 10% and non-progressive radiological loosening were reported as 2.0% and 3.8% respectively. At final follow-up, the overall revision rate was 4.9% (334/7132), deep infection rate was 0.4%, metal allergy/insensitivity rate was 1.6%, metal reaction rate was 0.3%, rate of peri-prosthetic fracture was 0.9% and aseptic loosening rates were 1.6%. This systematic review demonstrates that BHR results in satisfactory clinical outcomes, acceptable implant survivorship, low complication rates and modest surgical revision rates in the long-term at minimum 10-year follow-up.
DEVELOPMENT AND APPLICATION OF A METHOD FOR GENETIC DETECTION OF ENTEROBIUS VERMICULARIS IN SAMPLES OF PATIENTS WITH ENTEROBIАSIS
Authors:   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Kaneva Eleonora , Tsvetkova Nina ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Velcheva Desislava ,   MDL "Cibalab", Sofia, Bulgaria., Harizanov Rumen ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Kaftandjiev lskren ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Borisova Raina ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Videnova Mihaela ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., lvanova Aleksandra ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Alexiev Ivailo ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Dimitrova Reneta ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria., Pavlova Maria ,   National Centre of Infectious and Parasitic Diseases, Department of Parasitology and Tropical Medicine, Sofia, Bulgaria.
Published: January 2024

Purpose. The routine diagnosis of enterobiasis consists of a microscopic examination of perianal imprints on a transparent scotch tape for the presence of parasitic eggs. However, this method has low sensitivity when the number of eggs is small. The development of highly sensitive and specific methods, such as PCR, will increase the possibilities of detecting the parasite and will enable its genetic characterization. Material/Methods. The study was conducted from May 2022 to September 2022 and comprised 24 patients infected with Enterobius vermicularis. DNA was extracted from parasite eggs/adult worms using PureLink Genomic DNA Mini Kit (INVITROGEN), according to the manufacturer's instructions. Nested polymerase chain reaction (PCR) for detection of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was applied with two sets of primers. Results. The developed and described method for genetic determination of Enterobius vermicularis in samples from infected individuals is suitable and applicable to improve the diagnosis of the disease, as well as for further phylogenetic research of the parasite, which is of great importance for its successful treatment and control. Conclusions. Regardless of existing morphological diagnostic methods, genotyping studies concerning Enterobius vermicularis need to be deepened. Molecular-biological analyses increase diagnostic sensitivity, provide valuable knowledge about the geographic distribution and diversity of helminths, and allow the monitoring of therapy.
Nordic Youth Disability Summit 2023 – Meeting report
Authors:   Nordic Welfare Centre, Michelsen Gunnar
Published: January 2024

The Nordic Youth Disability Summit is the Nordic Council of Ministers' annual collaboration meetings with youth disability organisations. The aim of the meetings is to strengthen the perspectives of children and youth in Nordic cooperation on disability issues. This publication is a meeting report from the first Summit. Youth disability organisations met in Copenhagen in October 2023 to discuss current issues and challenges and identify areas of cooperation. This is a report on the results and implementations of the Summit. It presents statements developed during the summit on key topics in the Nordic Council of Ministers’ programme for cooperation on disability issues. The summit resulted in statements from a youth perspective on inclusive working life, cross-border obstacles in the Nordic region, how to take into account the child and youth perspective in the Nordic Council of Ministers’ policies and recommendations on inclusion in student democracy.
Delivery of precision medicine
Authors: Pirmohamed Munir , Prime Matthew , Nicol Dianne , Hassan Bass
Published: January 2024

Precision medicine is a rapidly evolving field that holds the promise of transforming healthcare. Realising this promise requires a comprehensive understanding of the complex healthcare systems in which precision medicine is delivered.

This webinar will explore the challenges and remaining barriers that must be overcome to translate recent medical advancements into real-world clinical practice with the panel discussing a wide range of topics, including the impact of precision medicine on healthcare systems and existing frameworks, therapies and technology, regulatory and ethical considerations, and much more.
Estudar o desconhecido, publicar o possível? A resposta à pandemia da covid-19 nas principais revistas Scopus em Ciências da Comunicação
Authors: Ribeiro Fábio , Silva Sónia , Perona Juan José
Published: January 2024

Quando a Organização Mundial da Saúde declarou a pandemia da covid-19, em março de 2020, os cientistas desconheciam essa doença. Simultaneamente, a Organização das Nações Unidas pediu esforços concertados na divulgação de dados científicos sobre o vírus. Do ponto de vista da Medicina e da Biologia, é conhecida a resposta à pandemia, que viria a ser decisiva para o combate ao vírus, no entanto pouco se sabe sobre as preocupações que ocuparam os investigadores das Ciências da Comunicação, num momento no qual era necessário comunicar mensagens de risco à população. A partir de uma amostra das 20 revistas com maior fator de impacto no índice Scopus, procurámos caracterizar a investigação que cruzou a pandemia com a comunicação, no primeiro ano dessa crise (março 2020-março 2021). Nos 42 trabalhos apurados sobre a covid-19, percebeu-se que os investigadores não trabalharam numa lógica de parceria internacional, desenvolvendo estudos em que sobressaem as preocupações sobre os impactos digitais da covid-19 na sociedade.
Paleolithic Hide Processing Activities
Authors:   한국구석기학회, KIM Kyung Jin
Published: January 2024

Hide, one of the various work materials used by the people from the Paleolithic onwards, is an essential material for making cloths and tents for survival. The technology and methods of hide processing and use, however, might be understood based on archaeological data and ethnoarchaeological studies because there aren’t many direct hide-related evidences in Paleolithic sites.
Researchers from Korea and abroad have undertaken studies on the use-wear analysis of the end-scraper, and they have found that different work materials, including wood, bone, antler, and hide, leave different traces behind. Of them, the trace formed by hide occupies the majority. Therefore, it can be known that the end-scraper was a specialized tool for processing hide. Ethnoarchaeological studies on this subject show the various stages of hide processing and usage: hunting animals; several stages of processing hide; and use. End-scrapers have been recovered from a lot of sites in the Paleolithic. This fact indicates that hide processing and use were essential for surviving in that era. Depending on the period, region, environment, animal species, purpose of hide use, type of end-scraper, its use method, and hide processing method, they are slightly different. These led to the establishment of the local technological tradition. These facts shed light on the different aspects of the hide processing method at the local level.