bluuebunny/crossref_metadata_2025 huggingface dataset:
An unusual case of a rotating toric phakic intra-ocular lens
Authors: Umesh Y , Singh Devika , Balasubramaniam Anand
Published: March 2021

An accurately sized Phakic Intra-Ocular lens (PIOL) helps achieve adequate vault which in turn also provides for rotational stability. Toric PIOL implantation was done for a case with bilateral myopic astigmatism. Both eyes had similar spherical equivalent and ocular biometric parameters; thus, same sized PIOLs were implanted. Right eye post-operative course was uneventful but left eye repeated rotation was noted. An inadvertently placed smaller sized PIOL in left eye could explain rotation. Re-evaluation confirmed similar ocular and PIOL parameters in both eyes, but a shallow vault (444 μ) in left eye compared to right (602 μ). Post PIOL extraction, measurement confirmed the left PIOL size to be lesser (11.61 mm) than the expected size (12.75 mm).
Clinical and spectral-domain optical coherence tomography findings in Valsalva retinopathy
Authors: Lambat Sarang P , Nangia Vinay B , Nangia Prabhat V , Mishra Swati D , Jaiswal Shreya J
Published: March 2021

Valsalva retinopathy is a prominent cause of premacular hemorrhage in young patients. We report the case of a young male patient with premacular hemorrhage due to Valsalva retinopathy who underwent Neodymium-doped Yttrium Aluminum Garnet (Nd: YAG) laser evacuation of the blood. Within 5 minutes, there was a significant clearance of the blood from the macular area. A week later we could demonstrate a vascular sign on fluorescein angiography. It is known that the source of blood in Valsalva retinopathy is the rupture of perifoveal capillaries. Based on the findings on fluorescein angiography we could postulate that the bleeding in our case could have been due to the rupture of a larger retinal venule.
Cataract secondary to iatrogenic iron overload in a severely anemic patient
Authors: Erol Mehmet Akif , Ozalp Onur , Atalay Eray
Published: March 2021

High levels of iron may be toxic and cause various pathologies in the human body, including the eye. Studies have shown increased iron concentration in certain subtypes of senile cataracts. High serum levels of its non-reactive depot form, ferritin, has also been associated with juvenile cataracts in hereditary hyperferritinemia-cataract syndrome. Whereas this form of hyperferritinemia is inherited, there is no report on cataract formation in iatrogenic hyperferritinemia. Herein, we report a 43-year-old case who was diagnosed with bilateral cataracts a few years after she received intensive intravenous iron replacement therapy for severe iron deficiency anemia.
Rituximab for refractory necrotizing scleritis and peripheral ulcerative keratitis secondary to antineutrophil cytoplasmic antibody-negative granulomatosis with polyangiitis
Authors: Chow Jun Y , Wan Muda Wan Norliza , Catherine Bastion Mae-Lynn
Published: March 2021

A 52-year-old woman was diagnosed with bilateral necrotizing scleritis (NS) and peripheral ulcerative keratitis secondary to the antineutrophil cytoplasmic antibody (ANCA)-negative granulomatosis with polyangiitis (GPA) as evidenced by increased erythrocyte sedimentation rate, bilateral multiple cavitation lung nodules, and persistent microscopic hematuria. Infective workup and autoimmune tests were negative including the ANCA test. She received multiple courses of high dose intravenous methylprednisolone, intravenous cyclophosphamide, and oral methotrexate. Multiple tectonic patching operations were performed. Despite all the treatment, the disease continued to progress. Eventually, few doses of rituximab were given and the disease was stable for at least a year without any reactivation.
A Review: Genetics Algorithms in Bioinformatics Tools
Authors: Najeb Mohammed Bafreen
Published: March 2021

Bioinformaticians study biological questions by analyzing molecular data with various programs and tools. Today, bioinformatics is used in large number of fields such as microbial genome applications, biotechnology, waste cleanup, Gene therapy, fingerprint and eye detection. The field of bioinformatics, is one of the most prominent areas that our need is increasing, and the demand for it is increasing day by day. Where dealing with this vital and biological information using advanced computer technologies to generate useful information and new discoveries. For this reason, vital bioinformatics is one of the domains that combines both interested and programming at the same time. It provides you with resources for self-learning, the most important information in the field of vital information, and asked questions of those wishing to learn this field. The term bioinformatics was first used in 1968 by Margret Dayhoff, which is a pioneer in this field, but its definition appeared for the first time in 1978. This science arose and developed in conjunction with the emergence and development of computers. It is also referred to as "computational biology."
Mechanical Properties Of Sandwich Composites Used For Aerofoil Shell Structures Of Wind Turbine Blade
Authors: BALIKOĞLU Fatih , Demircioğlu Tayfur Kerem , IŞIKTAŞ Ali
Published: March 2021

The grid-scored foams contribute significantly to the overall mechanical properties of the sandwich structures, such as aerofoil shell structure of wind turbine blades which are subjected to different loads under operating conditions. The goal of the present paper is to examine the four-point bending, flatwise and edgewise compression and in-plane shear behaviour of sandwich panels composed of composite face sheets of E-glass/ bisphenol-A epoxy resin and plain and grid-scored PVC foams. The four-point bending failure load of the grid-scored foamed sandwich beams increased by 28.1% compared to the plain foamed ones. The flatwise compression strength of samples with grid-scored foam increased by 546% compared to plain foamed samples. The resin grids contributed to an increase in the flat-wise compression stress inducing the core crushing. Under the edgewise compression load, using the grid-scored foam increased the maximum load values by only about 2.9% relative to the plain foam. The reason for this small difference can be addressed as the facings are more effective in carrying the edgewise loadings. With the use of the grid-scored foam, an increase of 38.2% was obtained in-plane shear strength compared to plain foamed sandwich beams. The resin grids improved bonding between the facings and PVC foam.
A INDOOR POSITION ROUTING (IPR) AND DATA MONITOR USING BLUETOOTH LOW ENERGY TECHNOLOGY (iBEACON-BLE): AN IMPLEMENTATION STUDY
Authors: Akgül Batur Alp , HAZNEDAR Bülent , YAŞAR Abdurrahman , ÇİNKILIÇ Mustafa Ersan
Published: March 2021

Rapid advancements in mobile industry have emerged new technological ideas and applications for researchers by allowing smart devices over the last decade. In recent years, the need for Indoor Position Routing (IPR) and Location-Based Advertisements (LBA) systems are increasingly common, IPR and LBA systems have been becoming very popular. Nowadays, it has become possible to create software and hardware applications for IPR and LBA in indoor environments, thanks to developments of different technologies. The development of the system should be based on low-cost technology, it should be suitable for integration and indoors operation. New options and possibilities for indoor locations are presented by the iBeacon-Bluetooth Low Energy (BLE) radio protocol. iBeacon-BLE supports portable battery-powered system that can be smoothly distributed at low cost giving it distinct advantages over Wi-Fi. Therefore, in this study, a technological infrastructure is created to solve the navigation problem in closed locations using iBeacon-BLE technology, a data monitoring information system is proposed for smart devices of currently available technology for IPR, LBA with using iBeacon-BLE. The localization of the objects based on iBeacon-BLE and their combination are determined using the measured data with the developed application. To build an IPR system for indoor environments, the available hardware, software, and network technologies are presented. The concept of the indoor monitoring system and the technologies can be used to develop the IPR system are presented. This system is made up of iBeacon-BLE sensor nodes, a smart device and a mobile application that provides IPR and LBA services by measuring the distance between Transmitter (TX) and Receiver (RX). The proposed model uses the trilateration method, it allows the mobile application to determine the exact location of the object at the micro-level size. The proposed model uses sensory data to identify and trilateration the object’s position.
IMPORTANCE OF ASCARIDIOSIS CONCERNING HUMAN AND ANIMAL HEALTH, PRESENT CONDITION AND SOLUTION PROPOSALS IN TURKEY AND THE WORLD
Authors: BILGILI Ali , HANEDAN Başak
Published: March 2021

Toxocariasis is a zoonotic parasitic infection, affecting millions of people and animals, commonly occurred, in the world. According to the seroprevalence studies, it is seen that exposure to this parasite is highly common in children living in temperate zones in the world. The geographic distribution of Toxocara canis is continuously expanded as a result of human and animal movements with global warming. Uncontrolled increase of human and animal populations in urban areas raises the importance of toxocariasis. Owned and unowned cats and dogs not administered treatment and wild animals create infection source for humans and other paratenic hosts by causing environmental contamination with eggs. Paratenic hosts like rodents, birds, and invertebrate animals play an important role in the spreading of the ascarid eggs. Infection in humans occurs in the result of consumption of larvae in the tissues of paratenic hosts (chicken, rabbit, pig and ruminants), drinking of dirty water, and close contact with contaminated soil and pet animals. Depending on these conditions stated, in the context of this review, concise knowledge was presented about the prevalence data in humans and animals of ascaridiosis in Turkey and the world, diagnosis, treatment and prevention measures.
The Impact of Scratch-Assisted Instruction on Computational Thinking (CT) Skills of Pre-Service Teachers
Authors: İlic Ulaş
Published: March 2021

The present study aimed to determine the effect of Scratch-assisted expressions and applications on the Computational Thinking skills of pre-service teachers. For this purpose, the research was designed with an exploratory sequential design, a mixed research method. Thirty-three pre-service teachers participated in the study. Data were collected with Computational Thinking Scale before and after the applications conducted in the Instructional Technologies course, and with a survey form developed by the author and face-to-face interviews conducted with the participants at the end of the course. Based on the data obtained, it was determined that the applications conducted in the course improved the Computational Thinking skills of the participants. Although the improvement did not differ based on gender, it was determined that the differences were significant based on creativity, algorithmic thinking, and critical thinking sub-dimensions. Furthermore, it was observed that there was a positive and significant correlation between Computational Thinking and academic achievement. Also, pre-service teachers stated that Scratch applications contributed to the acquisition of Computational Thinking skills. It was suggested that the present study findings would contribute to future studies on Computational Thinking acquisition in similar courses.
Social Entrepreneurship and Psychological Well-being in Teaching Candidates: Mediator Role of Hope
Authors: Asıcı Esra
Published: March 2021

The investigation and supporting variables related to the mental health of teaching candidates is important since teachers’ psychological traits will affect students’ personal, social, and academic development. In this paper, the intermediary role of hope in the relationship between the social entrepreneurship characteristics and psychological well-being of teaching candidates was investigated. The sample consisted of 855 teaching candidates were chosen randomly. The data were collected by using the Psychological Well-being Scale, the Social Entrepreneurship Characteristics of the Pre-service Teachers’ Scale, the Dispositional Hope Scale and a Demographic Information Form. In the analysis descriptive statistics, Pearson’s correlation, and regression-based bootstrapping method were used. The results showed that teaching candidates’ social entrepreneurship characteristics were positively and significantly correlated with psychological well-being and two components of hope (alternative ways of thinking and actuating thinking). Besides, it was found that alternative ways of thinking and actuating thinking had partial mediating roles in the relationship between teaching candidates’ social entrepreneurship characteristics and psychological well-being. The obtained findings were discussed in the light of related literature and suggestions were offered.
Investigation of the Organizational Commitment and Psychological Well-being Levels of Academicians
Authors: Yalçın Sinan , Akan Durdağı , Yıldırım İsa
Published: March 2021

In this research, which aims to investigate the organizational commitment and psychological well-being of academicians, the quantitative research method was employed. The research was designed in the relational screening model. The sample of the research consisted of 132 academicians at the Erzincan Binali Yıldırım University located in the Eastern Anatolia Region of Turkey in the 2018-2019 academic year.  The research data were collected with the organizational commitment and psychological well-being scales. The data of the research were analyzed with the SPSS package program. The frequency, t-test, one-way (ANOVA) analysis, correlation and regression analysis were applied in the analysis of the data. According to the results reached in the study, the psychological well-being levels of the academicians were found to be high, their organizational commitment levels were at a moderate level. As it was analyzed in terms of the sub-dimensions of the organizational commitment, the emotional commitment of the academicians was found to be high, normative and the attendance commitment was at a moderate level. According to another result reached in the study, a positive significant relationship was encountered between the psychological well-being levels of the academicians and their organizational commitment levels. According to another result, the psychological well-being levels of the academicians were a significant predictor on the emotional and normative commitment, which are sub-dimensions of the organizational commitment, but was not a significant predictor of the attendance commitment.
Experts’ Model-Based Reasoning and Interdisciplinary Understanding of Carbon Cycling
Authors: You Hye Sun , Delgado Cesar , Deatley Kaitlyn
Published: March 2021

The global carbon cycle (CC) is a key environmental literacy issue related to climate change, ocean acidification, and energy sustainability. Understanding the CC requires interdisciplinary knowledge informed by multiple science disciplines such as biology, chemistry, earth science, and physics. To examine the core principles and interdisciplinary nature of CC, we interviewed 10 experts from various science disciplines and asked them to create their own models of the carbon cycle. We utilized the data to identify emerging core concepts of CC and discover commonalities and differences across the experts’ models in the context of interdisciplinary understanding. The concepts and interdisciplinarity were compared with those of CC-related topics in the U.S. Framework and Next Generation Science Standards. Most experts demonstrated a breadth of interdisciplinary knowledge based on their disciplinary backgrounds. The experts hold a wider set of ideas about CC than is present in the standards. Many topics not included in the standards could feasibly be added (e.g., the process of carbon sequestration into the ocean and rocks and CO2 emissions by volcanic activity). This study generates concrete recommendations for science standards to guide the revision of existing curricula or to guide the development of new interdisciplinary approaches to teaching global CC.
Epistemological Conceptions in Teacher Education: A Study with Students from Luanda
Authors: Victor Eufrásia Corrêa , Costa Maria Conceição , Bonito Jorge
Published: March 2021

Epistemology plays an important role in detecting learning difficulties in a given field of knowledge and in directing strategies to eliminate them. This quantitative study aimed to get to know the perceptions of 624 students, related to the nature of science and science teaching and learning. The cross-sectional survey, based on the Inventory of Teacher’s Pedagogical & Scientific Beliefs (INPECIP) questionnaire, was applied to the students who attended the 10th, 11th and 12th grades of teacher training courses, in a school in Luanda. The results reveal a clear majority agreement with the theoretical and conceptual frameworks presented, in decreasing manner, from the “didactic model” through the “learning theory”, the “image of Science” and the “teaching methodologies”. The regression model highlights that the course attended clearly influences the epistemological conceptions of the respondents.
Examination the Knowledge of Student Understanding of Pre-Service Science Teachers on Heat and Temperature
Authors: Inaltekin Tufan , Akcay Hakan
Published: March 2021

The aim of this study is to examine the "Knowledge of Student Understanding (KSU)” of pre-service science teachers on "Heat and Temperature" topics. The sample of the research consists of 268 pre-service teachers studying at the 4th grade in the science teaching program of five different universities in Turkey. This research is a case study. The data of the study are collected with "Student Thinking Comprehension Test” and "Interview Form". "Scoring Rubrics for Knowledge of Student Thinking" and "Rubric for Analysis of Interviews" are used for the analysis of data. The data of the research are analyzed descriptively on the basis of these rubrics. The results of the study reveal that the vast majority of pre-service science teachers cannot effectively diagnose the student’s inaccurate knowledge that emerges in solving specific problems in “Heat and Temperature” topics. In addition, it is shown that the majority of pre-service science teachers have a little knowledge regarding the difficulties and limitations of students while learning "Heat and Temperature" subjects. According to these results, the KSU of the pre-service science teachers in "Heat and Temperature" topics is insufficient in the process of starting their profession.
Evaluation of the Motivation Levels of Physical Education Teachers
Authors: Kasımoğlu Murat
Published: March 2021

A number of psychosocial determinants have been associated with a significant proportion of teachers with adjustment problems and low levels of motivation. The motivation of physical education teachers is a critical factor in their approach to students and in achieving lesson outcomes. In this study, it was aimed to evaluate the motivation levels of physical education teachers in terms of some variables. In the study, based on the descriptive survey model, physical education teachers were compared according to the variables of gender, age, marital status and type of school. The sample of the study consists of 206 physical education teachers working in secondary schools and high schools in Aksaray, Karaman and Konya provinces of our country. Intrinsic and extrinsic motivation scales were used to collect research data. According to the results of the study, the extrinsic motivation levels of the teachers were found to be partially low. The extrinsic and general motivation of physical education teachers working in private schools is very low. According to the findings of the study, the motivation levels of physical education teachers differ according to the variables of gender, age, marital status and type of school.
Collaborative Governance: Re-Enactment Share Understanding in the Process of Agricultural Food Management in Karawang Regency
Authors: Gracino Marvin Angelo , Priyanti Evi , Azijah Dewi Noor
Published: March 2021

Sustainable Food Agricultural Land Protection is a system and process in planning, developing, utilizing, controlling, and monitoring agricultural land that is determined to be consistently protected in order to produce staple food for national food security. Currently, food agriculture land in Karawang Regency is increasingly under threat along with the rapid development of the industrial sector in the area and threats from the surrounding area. Not only because of the conversion into industrial land, but the existence of factories around it also threatens soil fertility and water quality due to the factory waste itself. The focus in this paper is how the Karawang Regency Government carries out Collaborative Governance in protecting sustainable food agricultural land. In this study, the authors used a qualitative method with a phenomenological approach. The purpose of this research is to explain how to study and analyze the implementation of policies on the protection of sustainable agricultural land with one of the stages of collaborative governance from Ansell and Gash, namely share understanding. The results showed that the Government of Karawang Regency has succeeded in conducting share understanding in collaborative governance well because it has the same goal, namely to create national food security. Openness and interdependence with each other fosters a sense of understanding. However, the community's understanding regarding PLP2B is felt to be lacking because they have not received good socialization from the Karawang Regency Government.
The Effect of Stimulus Policies and Risk-Based Capital Levels on Solvency at PT. Indonesian Takaful using Sharia Principles during the Majeur Force Period (Covid-19 Pandemic) in Indonesia
Authors: Suyatna Nano
Published: March 2021

The Covid -19 pandemic is a massive disaster, impacting various sectors of the economy including the Islamic principle insurance sector. The government through the Financial Services Authority (OJK) in dealing with these problems has issued a stimulus policy so that the Islamic principle insurance sector is still able to maintain the level of solvency and risk based capital is maintained. The purpose of this study is to determine the influence of the Stimulus Policy and the level of Risk Based Capital on the level of solvency of sharia-based insurance companies during the Covid-19 Pandemic. The method used is descriptive method with a simple statistical approach. The results show: 1. There is a positive influence of the Stimulus Policy on the Solvency Level of the Islamic principle insurance company sector, 2. There is a positive influence on the Level of Risk Based Capital on the Solvency Level of the Islamic Principle Insurance Company sector, 3. There is an influence of the Stimulus Policy and Level of Risk Based Capital on Simultaneous level of solvency in Islamic principle insurance companies. From the research results, it can be concluded that the Stimulus Policy and Risk Based Capital Level that has been set by the regulator is right on target.
Design of Corporate Performance Assessment Model using the Total Performance Scorecard at PT. Sawitto Indah Berkah
Authors: Imbrani Hari , Rapida Ida
Published: March 2021

PT. Sawito Indah Berkah is a medium scale company engaged in the LPG Non-Public Service Obligation (NPSO). The company has not applied standard standards in performance assessment. This study aims to determine the performance appraisal model currently used and to design a performance appraisal model using the Total Performance Scorecard. This study uses a survey method with a qualitative approach and the type of research is descriptive modeling. The data collection technique used triangulation. The results showed that the company only applies a financial perspective in measuring performance. This research can provide useful information about the importance of designing corporate performance appraisals. Also, it is expected to be able to assist the company in evaluating its financial function, marketing function, operational function, and human resource function properly.
Koronavirüsün Kardiyovasküler Sistem Üzerine Etkileri Işığında Sporcuların Yeniden Sahalara Dönüşünün Değerlendirilmesi
Authors: ÇAYIRLI Sercan , KARTAL Alper , YILMAZ Ozan , GÜNGÖR Hasan
Published: March 2021

Tüm dünyayı etkisi altına alan ve 2020 yılının en büyük sağlık sorunu haline gelen koronavirüs-19 (Covid-19) enfeksiyonu endotel disfonksiyonuna yol açıp tüm organları etkilemesine rağmen temel etkilerini kalp ve akciğer üzerinde göstermektedir. Profesyonel sporcular risk grubu olarak gösterilmemesine rağmen birçok takım veya sporcular virüs ile enfekte olmuştur. Özellikle sosyal mesafenin korunamadığı sportif faaliyetler sırasındaki bulaş sonrasında semptomatik ve asemptomatik hastalar ortaya çıkmıştır. Günümüzde enfeksiyonu geçiren sporcuların sahalara dönüşü ile ilgili yeni algoritmalara ihtiyaç duyulmaya başlanmıştır. Bu derlemede Covid-19 hastalığı geçiren profesyonel sporcularda virüsün kardiyovasküler sistem üzerine etkilerinin göz önüne alınarak sporcularda sahalara yeniden dönüşünün nasıl olması gerektiğinin tartışılması amaçlanmıştır.
Üniversite Öğrencilerinin Rekreatif Faaliyetlere Yönelik Tutumları ve Boş Zaman Motivasyonlarının İncelenmesi
Authors: ARGUZ İrfan , ERDOĞDU Murat
Published: March 2021

Bu araştırmanın amacı, üniversite düzeyinde eğitim-öğretim gören öğrencilerin boş zaman tutumlarını ve boş zaman motivasyonlarını çeşitli değişkenler açısından incelemektir. Araştırmanın örneklem grubunu, Necmettin Erbakan Üniversitesinde öğrenim gören ve tesadüfi yolla seçilen 1071 gönüllü öğrenci oluşturmaktadır. Çalışmada kullanılan, Ragheb ve Beard (1982) tarafından geliştirilen “Leisure Attitude Scale: LAS” “Boş Zaman Tutum Ölçeği” nin Türkçe uyarlaması Akgül ve Gürbüz (2011) tarafından yapılmıştır, diğer ölçek “Boş Zaman Motivasyon Ölçeği” ise Pelletier, Vallerand, Blais ve Brière tarafından geliştirilmiştir, ölçeğin Türkçe uyarlaması güvenirliği ve geçerliği Mutlu tarafından (2008) yapılmıştır. Ölçeklere yönelik konuların farklılaşma durumunu ortaya koymak amacı ile ANOVA testi kullanılmış olup, analizler sonucunda anlamlı farklılığın ortaya çıkması durumunda, farklılığın hangi gruplar arasında olduğunu belirlemek için varyansların homojenliği kontrol edilmiştir. Varyansların homojen olması durumunda çoklu karşılaştırma testlerinden tukey testi kullanılmıştır. İki ölçek arası ilişkiyi değerlendirmede ise Korelasyon analizinden yararlanılmıştır. Tanımlayıcı istatistik testi kullanılmıştır. Verilerin istatistiksel analizinde ve yorumlarda, p<0,05 anlamlılık düzeyi dikkate alınmıştır. Sonuç olarak; Öğrenciler günlük yeterli boş zaman süresine sahip olduklarını beyan etmişlerdir ve günlük boş zaman sürelerinin boş zaman faaliyetlerine yönelik tutumlarını ve motivasyonlarını etkilediği görülmüştür. Öğrencilerin aylık gelir durumları incelendiğinde orta düzey bir aile yapısına sahip oldukları görülmüş, bu da öğrencilerin boş zaman tutumlarını ve motivasyonlarını etkilediği ortaya çıkmıştır
MANAGEMENT OF MADHUMEHA ACCORDING TO AYURVEDA – A CASE STUDY
Authors: Bansode Nitin Bhairavnath , Chandekar Prashant Dhanaraj , Dhumne Nilesh Dnyaneshwar
Published: March 2021

Diabetes mellitus is the disease afflicting mankind since a very long time. Over 30 million people have been diagnosed with Diabetes in India and it is one among the cause for morbidity, which makes the life of individual miserable. In Ayurveda, Diabetes mellitus can be understood as Madhumeha which is one among the Vataja Prameha. Lakshana pertaining to Madhumeha as per the classical text are Prabhoota Mutra, Aavila mutra etc. In the present case study, a 45 years old male patient came to Smt. Vimladevi Ayurvedic Medical College and Hospital OPD with complaints of pain in smaller joints and increased fre-quency of micturition. Through Physical findings and Investigations, the diagnosis leads to Madhumeha (Diabetes mellitus). The treatment plan opted was Shamana Aushadhi, Proper Diet and Change in Lifestyle would be an apt management in such case.
EFFECT OF PERINEAL REPAIR AND MUSHAKADI TAILA MATRABASTI IN
MANAGEMENT OF RECTAL PROLAPSE (GUDABHARMSA): A CASE STUDY
Authors: Maheshwari Sapna , Shah Harshit , Patel Pragnesh
Published: March 2021

Rectal prolapse can present in a variety of forms and is associated with a range of symptoms including pain, incomplete evacuation, bloody and/or mucous rectal discharge, and fecal incontinence or constipa-tion. Complete external rectal prolapse is characterized by a circumferential, full-thickness protrusion of the rectum through the anus, which may be intermittent or may be incarcerated and poses a risk of strangu-lation. There are multiple surgical options to treat rectal prolapse, and thus care should be taken to under-stand each patient’s symptoms, bowel habits, anatomy, and pre-operative expectations. We propose an al-gorithm based on available outcomes data in the literature, an understanding of ano-rectal physiology, and expert opinion that can serve as a guide to determining the rectal prolapse operation that will achieve the best possible postoperative outcomes for individual patients. Mushakadi Taila Matrabasti will be given in Sushrut Samhita as a treatment1 with perineal repair. So, it is really needed to find a safe, easier, less com-plicating, cost effective and fruitful approach for the management of disease through Ayurveda. A 62year old male patient came to the hospital with chief complaints of protrusion of mass from the anus with mu-cous discharge, constipation since last 5 years. He was diagnosed as complete rectal prolapse. Considering the signs and symptoms of rectal prolapse, the treatment of rectal prolapsed was planned with perineal re-pair and Mushakadi Taila Matarabasti as per mentioned in the treatment of Gudabhransha by Aacharya Sushruta.
CROSS-SECTIONAL ASSESSMENT OF ASSOCIATION BETWEEN GRADE OF AS-THI SARATA AND INCIDENCE OF DENTAL CARIES
Authors: Kshitiza Pathak , Akshay Pathak
Published: March 2021

Dashavidha Karanadi Pariksha (Ten-fold examination) elaborated in Charaka Samhita imparts complete knowledge of patient’s condition by means of specific investigations. It is done for knowledge of lifespan, degree of strength of body and disease and exact treatment perspective. Accordingly, a patient should be examined in respect of Dhatu Sarata (excellence of body tissues) i.e. as per the best qualities of Dhatu (body tissues). Drudh Danta (strongness of teeth) has been described as a characteristic of Asthi Sarata. Thus, an observational cross-sectional study was planned to assess the probable association between grada-tion of Asthi Sarata (excellence of Asthi Dhatu-bone tissue) as Uttama (excellent) -Madhyama (moderate)-Heena (poor) and incidence of dental caries. Total 200 volunteers were assessed for their grade of Asthi sarata (excellence of Asthi Dhatu-bone tissue) with the help of a questionnaire related to general descrip-tion of Asthi Sara Purusha (person with excellence of bone tissue) as per Charaka Samhita. Dental inspec-tion of each participant was done to check for presence and absence of dental caries. The association be-tween Sarata grade of each individual and incidence of dental caries was established by statistical analysis. Statistical tests showed that Asthi – Sarata (excellence of Asthi Dhatu-bone tissue) and occurrence of den-tal caries were dependent of each other.
A COMPARATIVE CLINICAL STUDY ON THE EFFECT OF ASHTAVARGAM KASHAYA AND GANDHARVAHASTHADI KASHAYA IN THE MANAGEMENT OF KATIGRAHA w.s.r. TO LUMBAR SPONDYLOSIS
Authors: D P Abeena Raj , Acharya Shripathi
Published: March 2021

Katigraha is a condition in which the vitiated Vata is localizing in the Katipradesha and producing stiff-ness and pain. These symptoms are similar to Lumbar Spondylosis. The degenerative changes due to aging or trauma, changing in lifestyle & work pattern, unhealthy food habits causing nutritional deficit etc., are causing Dhatukshaya and Margavarodha. Here Ashtavarga & Gandharvahasthadi Kashayas are taken to evaluate the effect on Katigraha. Totally 40 patients of Katigraha were selected, divided in to two groups equally. Group A treated with Ashtavargamkashaya and Group B treated with Gandharvahasthadi Kashaya for 30 days. In group A, 55% patients got moderate improvement and 40% patients with mild im-provement in group B, 5%got moderate improvement and 60% got mild improvement. It is concluded that in general statistically significant results were seen in both the groups. AshtavargamKashaya showed better efficacy than Gandharvahasthadikashaya.
A CLINICAL STUDY TO EVALUATE THE EFFICACY OF KHADIRADI VARTI IN KARNINI YONI VYAPAD WITH SPECIAL REFERENCE TO CERVICAL EROSION
Authors: Parvin Ruksana , Balen Baishya , Yanbeni Humtsoe
Published: March 2021

Objectives: Karnini Yoni Vyapad which is one among twenty Yoni Vyapads is a common problem of the females in the reproductive age group. Since the symptoms of Karnini Yoni Vyapad as explained in Sam-hitas has got similarity with cervical erosion in modern perspective so it has been taken into consideration in this study. This study aimed to assess the efficacy of the trial drug i.e. Khadiradi Varti in the treatment of cervical erosion.
Method: 30 numbers of patients suffering from Karnini Yoni Vyapad (Cervical erosion) were selected from OPD and IPD and were treated with Khadiradi Varti per vaginally following all aseptic measures, once a day preferably at bedtime for 7 consecutive days after completion of menstrual cycle. Such 3 cy-cles were performed for each patient. Result: The trail drug have efficacy in reducing severity of signs and symptoms like degree of cervical erosion (Yoni Karnika), cervical odema (Yoni Soth), discharge per vagina (Yoni Srava), bleed on touch (Rakta Srava) associated with Karnini Yoni Yyapad without having any tox-icity or adverse effect on the body.
CLINICAL EVALUATION OF ANUBHOOT YOGA IN THE MANAGEMENT OF
VATARAKTA W.S.R. TO HYPERURICEMIA
Authors: Gupta Monika , Kangotra Shakshi
Published: March 2021

Vatarakta is a Vatavyadhi Prabheda. The illness is considered to be the finest illustration of an Avarana Vyadhi, as an opening from the etiopathogenesis to the complications, the illness follows the characteristic presentation of Avarana. Compared with the other Vatavyadhi, Vatarakta possesses a special place in the literature, due to its high prevalence in the society, increased incidence as age advances, stepwise succes-sion, and so on. From the overall view of the etiology, it is obvious and unambiguous that the precise etio-logical factors of Vata Dosha as well as Rakta Dhatu are accountable for the causation of illness. The ety-mology and symptomatology of Vatarakta is very much similar to that of Hyperuricemia. Whatever be the grounds, an obstruction in the path of Rakta Dhatu is the core pathology of the disease. In this single group study, 30 patients diagnosed of Vatarakta were selected randomly for an open trial of Anubhoot Yoga for a period of 60 days with life style modifications to provide safe ,effective and conservative treatment for Vatarakta w.s.r.to hyperuricemia In the present study as per the clinical data, Anubhoot yoga is the reliable therapeutic treatment of Vatarakta.
A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF SANKHAPUSHPI CHOORNA WITH SAHAPANA OF KSHEERA AND DRAKSHA SWARASA IN NIDRANASHA W.S.R.TO PRIMARY INSOMNIA
Authors: A. K Sabeena Susmitha , D’souza Zenica
Published: March 2021

Background: Sleep has occupied a special place in human concern. It has been rightly stated by Acharya Charaka that happiness and misery, proper and improper growth, good strength and weakness, potency and sterility, knowledge and ignorance, life and death of an individual depend on the quality of sleep. The condition of Insomnia has tendency to damage the person’s daily life, including his social and occupational life. Considering this Sankhapushpi Choorna with Go ksheera and Draksha Swarasa were selected for this study. Sankhapushpi Choorna has the property of Nidrajanana and Medhya. Ksheera has the property of VataPitta Shamana and Draksha has the property of Pitta Kapha Shamana, Rakta Prasadana.
Methods: The study was Randomized parallel Group comparison clinical study. The study was conducted in 60 subjects for a period of 30 days. Subjective and objective parameters were documented at base line, 7th day, 15th day and on 30th day. Observations were analysed and findings were evaluated by using statis-tical methods.
Results: This study shows that both Sankhapushpi Choorna with Ksheera and Sankhapushpi Choorna with Draksha Swarasa have significant effect in Nidranasha.
Conclusion: The result obtained was both Sankhapushpi Choorna with Ksheera and Sankhapushpi Choorna with Draksha Swarasa have significant effect in Nidranasha. There is no significant difference in effect of Sankhapushpi Choorna with Ksheera and Sankhapushpi Choorna with Draksha Swarasa.
SARJIKAKSHARA TAILA-A KARNAPOORANA DRAVYA IN BADHIRYA
Authors: 1 Ramya , Pasha S. M.
Published: March 2021

Badhirya or hearing loss is the disease condition where in there is partial or total inability to hear. There are many formulations mentioned in Ayurvedic classics. One among them is Sarjikakshara taila indicated for treatment of Badirya in the form of Karnapoorana. Objective: To Prepare Sarjikakshara Taila according to the classical procedure and to conduct its physicochemical analysis. Method: In the present study, the Taila was prepared according to the method given in Sharangdhara Samhitha. The physicochemical proper-ties were checked after completion of Taila. Result: The physico-chemical analysis showed that saponifi-cation value, acid value, iodine value etc were within normal limits. Conclusion: The Taila was analysed to establish the parameter for its identification and purity. Its effectiveness in treating the disease Badhirya. Further Pharmaceutical analysis, clinical and experimental studies has to be conducted to prove the effect of this formulation in management of Badhirya.
PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL
CHARACTERIZATION OF TENDER LEAVES OF COMBRETUM LATIFOLIUM BLUME - A FOLKLORE MEDICINAL PLANT
Authors: S Ravikrishna. , Prabhu Suchitra. N.
Published: March 2021

Objective: The study is undertaken with the intention to document the pharmacognostic characters in order to ascertain identity, quality and authenticity of the crude drug. Further the Phytochemical class predomi-nantly to which the plant belongs will be of great importance contributing to its biological activity and ther-apeutic use. The tender leaves of Combretum latifolium(C. latifolium)Blume. are used to render the immune system strong. Combretum species are extensively used in traditional medicinal system from inflammation to diuretic. The present study is a step to unleash its phytochemical characterization which may be respon-sible for its biological activity. Pharmacognostic characters will serve the drugs identity and authentication. Materials and methods: Sample of crude plant material were collected around Udupi area and its identity was thus confirmed by botanist. Macro-microscopic study of the preserved specimen in the fixative was conducted in the department of Pharmacognosy and preliminary phytochemical test and HPTLC fingerprint of the leaf extract was carried out as per testing protocols. Results and Discussion: The unique microscopic characters of this leaf is arc shaped collateral vascular bundle which is encircled by pericylicfibre. Tri-chomes were found to be absent. Standardization parameters such as moisture content (8.97±0.01), total ash (5.83±0.16), acid insoluble ash (0.10±0.00), water soluble ash (3.19±0.01), alcohol soluble extractive value (7.79±0.01), water soluble extractive value (27.06±0.00) are conducted as a part to prove quality standards proposed by the guidelines. Conclusion: Microscopic characters, standardization parameters, HPTLC will serve as a fingerprint revealing various phytoconstituents pertaining to this plant material. Phy-toconstituents belonging to chemical groups such as alkaloids, carbohydrates, steroids, tannins, flavonoids, phenols, coumarins, resins were found to be present through qualitative screening tests. Proximate analysis involving total fat, fibre, protein, carbohydrates will appraise the total calorific value calculated by the formula (Carbohydrate ˟ 4) + (Fat ˟ 9) + (Protein ˟ 4).
TOXICOLOGICAL STUDY OF SURYASHEKHARA RASA
Authors: Patil Shanta , Medikeri Surekha S
Published: March 2021

Suryashekhara Rasa is unique mercurial preparation, which contains Parada, Gandhaka, Hingula and Vatsanabha. The quantity of Vatsanabha is equal to the sum of other ingredients, and also its antidote (Tankana) is not mentioned in this formulation. To ensure that the drug is devoid of toxicity and harmful effects, assessing the level of toxicity is important. So, this research work is an attempt to perform acute and sub-acute toxicity evaluation of Suryashekhara Rasa. Acute toxicity study of test drug was carried at a limit dose of 2000mg/kg orally in albino mice. For sub-acute toxicity Suryashekhara rasa was adminis-tered at therapeutic equivalent dose (TED) (0.35mg/kg bw po), TED x 2 (0.70mg/kg bw po) TED x 5 (1.75 mg/kg bw po) for 28 days. Acute toxicity result showed that drug did not produce any signs and symptoms of toxicity or mortality up to an oral dose of 2000 mg/kg in albino mice. The data generated during sub-acute toxicity study are indicated that it is mild toxic substance for sub-acute administration at TED dose level, may be because of alkanes which are found in functional group of aconitum ferox.
EVALUATION OF SMRUTIRHASA (MEMORY LOSS) IN OLD AGED INDIVIDUALS AND EFFECT OF BRAMHI SIDDHA GHRITA ON SHORT TERM MEMORY LOSS
Authors: Tappe Bhargav G. , Sant Sampada S , Gawai Abhijeet
Published: March 2021

Memory disorders are increasing at fast rate in modern society. Neurological disorders like Alzheimer’s disease, Parkinson’s disease also affect memory. Due to ageing process a greater number of old aged indi-viduals are facing problem of memory loss i.e. Smrutirhasa (Memory Loss) which leads to their behavior-al change and cognitive impairment ultimately leads to land them in senile dementia. In first part of study 100 old aged individuals were randomly selected for evaluation of Smrutirhasa in second part of study, effect of Bramhi Siddha Ghrita was observed for period of 2 months after obtaining Short term memory status of individuals having Smrutirahsa. According to statistical analysis 66% of individuals above 60 years were having Smrutirhasa and treatment by Bramhi Siddha Ghrita shows significant result over short term memory loss in them.
A COMPARATIVE CLINICAL STUDY OF KADALI KSHARA AND APAMARGA KSHARA IN THE MANAGEMENT OF CHARMAKEELA (WARTS)
Authors: Badami Aqlak Husen , N. B. Mashetti , P. G. Gannur , Gujjar Rakeshkumar
Published: March 2021

Charmakeela is one of the Kshudraroga mentioned by Acharya Sushrutha and Vagbhata. Vyanavata combines with Kapha produces piles on the exterior of the skin resembling a nail which is static or immov-able and rough is called as Charmakeela. Based upon the clinical features explained in Ayurveda, Char-makeela can be correlated with that of warts. Objective: The present study was to evaluate the comparative effect of Kadalikshara and Apamargakshara in the management of Charmakeela. Methods: 40 patients were randomly selected and divided into 2 groups. Results: The statistical Analysis the study reveals there is no significant difference between found statistically between Kadalikshara and Apamargakshara, so both KadaliKshara and ApamargaKshara are having same Qualitative Equanimity effect of treatment on the disease. Conclusion: As observed from the results the total removal of Charmakeela was possible in all cases and it proves the authenticity of the classical ayurvedic reference which state that Charmakeela can be removed by the application of Prathisarneeyakshara. In this study the action of the drugs KadaliKshara and ApamargaKshara on the removal of Charmakeelais well established. The clearance may be faster in case of thin lesions and it may be slower in case of thicker lesion because of variations in the thickness of morbid growth in all patient, removal of lesion of Charmakeela there may be slight blackish brown discol-ouration occurs at the site of lesion was observed. This may be considered as Samyakdagdhalaxanas of Kshara Karma which will disappear gradually.
A RANDOMIZED COMPARATIVE CLINICAL STUDY ON LODHRADHI LEPA AND ARJUN TWAK LEPA WITH JALOUKAVACHARANA IN THE MANAGEMENT OF MUKHADUSHIKA (ACNE VULGARIS)
Authors: Rathod Sagar , N. B. Mashetti , P. G. Gannur , Gujjar Rakeshkumar
Published: March 2021

Mukhadushika is the most troublesome and most common skin care problem. The symptoms of Mukha-dushika resembles with Acne Vulgaris. Objective: The present study was to evaluate the comparative ef-fect of Lodhradilepa and Arjuna twak lepa with Jaloukavacharana in the management of Mukhadushika. Methods: 40 patients were randomly selected and divided into 2 groups. Results: Both the groups showed statistically significant results on all assessment criteria. On comparison between 2 groups, there is no sig-nificant difference in assessment criteria except in the size in which Group-2 was more effective than Group-1 and Number of pidaka in both groups found to be insignificant. Interpretation and conclusion: Jaloukavacharana serve as a Shodhana karma here as there is involvement of Rakta dhatu in the Sam-prapti & Lepa is one of the treatment modalities for Mukhadushika mentioned in classics. Both Arjuna le-pa and Lodhradi lepa along with application of Jalouka showed statistically highly significant on all the assessment criteria like vedana etc. GAGS Score and IGA criteria except in the size in which Group-2 was more effective than Group-1 and Number of Pidaka in both groups found to be insignificant.
CLINICAL TRIAL TO EVALUATE AN EFFICACY OF SHINSHAPATWAK GHAN-VATI IN THE MANAGEMENT OF GRUDHRASI (SCIATICA)
Authors: Shinde Devyani , Barhate Purti , Rane Pawan , Kanzode Sonam
Published: March 2021

Introduction: A normal daily life without moving the limbs is almost impossible for any human being from the time immemorial to ultramodern life. Though the movements of the limbs are so important, these are the parts frequently vulnerable to many diseases. The most common disorder which affects the move-ments of the leg is low back pain, out of which 40% of persons will have radicular pain which comes un-der sciatic syndrome. Such presentation’s been present in olden period too and was called by the name Grudhrasi.
Material & Method: An Open study with Shinshipatwak Ghanavati with Dugdha Anupana was done in 30 patients of Grudhrasi.
Result: In total score it was found that after finishing treatment, improvement of 79.39% observed. Result was statistically highly significant after 21 days (P<0.001). Shinshipatwak yoga was more effective in Kaphanubandhit Grudhrasi.