bluuebunny/crossref_metadata_2025 huggingface dataset:
“Assessment of window period knowledge among STEMI patients in a tertiary care hospital, Puducherry: A cross-sectional study.”
Authors: KUTHUBUDEEN MOUHAMED NAZAR , S KASIPANDIAN
Published: September 2024

Background:The rising cardiovascular disease (CVD) epidemic in South Asia, including India, has been a significant concern over the past three decades. ST-elevation myocardial infarction (STEMI) is a severe manifestation of CVD that requires prompt reperfusion therapy to prevent a poor prognosis. Despite this, over 50% of individuals with acute myocardial infarction (AMI) either die in the emergency department or before reaching a hospital within an hour of symptom onset. In India, only 0.8% of patients arrive within the critical first hour, with most seeking treatment after 12 hours. Delays in seeking care often lead to preventable complications, highlighting the need for increased public awareness about the STEMI window period and the importance of timely hospital arrival.
Material and methods: The present study was cross sectional study carried out among STEMI patients both new and old cases more than 18 years. The data was collected in a semi structured questionnaire after informed consent. Statistical analysis was done using descriptive statistics.
Results: This study assessed 90 patients with a mean age of 51.01 years. The group included 60% males and 40% females, with educational backgrounds ranging from illiterate (8.9%) to college-educated (41.1%) and school attendees only (50.0%). Findings revealed varying knowledge about the critical timing for seeking medical attention following chest pain: 35.6% of participants recommended arriving at the hospital within 1-2 hours, while 31.1% suggested 3-5 hours. Notably, 22.2% and 11.1% recommended waiting more than 6 hours and 12 hours, respectively. Overall, 58.9% of participants demonstrated a good understanding of the risks associated with late arrival, with all individuals aged 70-79 being aware of the associated mortality risk (p<0.05). Additionally, 63.3% of the study population recognized that chest pain is unrelated to gas issues, with the 60-69 age group showing a high level of understanding (72.7%). Knowledge about the importance of ECG for diagnosing heart attacks was good among 57.8% of participants, with the 40-49 age group demonstrating particularly strong knowledge (70%). Furthermore, 58.8% of participants understood the critical nature of heart muscle damage occurring every second during a heart attack.
Conclusion:Delay in treatment for acute coronary syndromes is a major contributor to the morbidity burden of cardiovascular disease. Hence awareness is critical for the general public to know about the window period of STEMI and timely arrival to the hospital for early management.
An autopsy case report of a patient with myxedema coma
Authors: Tetsuka Syuichi , Ashida Chisa , Ueno Shoichiro , Nakamura Ryuta , Nihei Mio , Ogawa Tomoko , Nakazato Yoshimasa
Published: September 2024

Background
Myxedema coma is a rare disease in which the underlying metabolic function is impaired due to hypothyroidism. Although myxedema coma has a very low prevalence, it has been associated with a high mortality rate. However, autopsy cases of myxedema coma have not yet been reported. Case presentation: This study presents an autopsy case of myxedema coma in an 82-year-old man with hypothyroidism, despite receiving treatment with levothyroxine. The patient suffered from head trauma and cold exposure, resulting in disturbance of consciousness and hypothermia. Upon arrival at our hospital, the patient exhibited severely impaired consciousness and had a body temperature of 27.2℃, oxygen saturation of 71%, heart rate of 40 beats/min, and hypotension. The thyroid hormone levels decreased with the thyroid-stimulating hormone level being 14.10 µIU/mL and free T4 being 0.57 ng/dL. Therefore, the patient was diagnosed with myxedema coma and underwent levothyroxine treatment (200 µg daily), noninvasive positive pressure ventilation, and adrenaline administration. However, the patient did not respond to those treatments and died six days after admission. The autopsy findings indicated pericardial and pleural effusions and, histologically, edematous adipose tissue infiltration containing mucopolysaccharides throughout multiple organs, such as the heart, thyroid, pancreas, and kidney.
Conclusions
Although gelatinous degeneration of bone marrow tissue due to mucopolysaccharides with edema was previously reported in patients with severe hypothyroidism, no reports on the other visceral adipose tissues were found. This autopsy case might present pathological changes resembling gelatinous degeneration in various organs which are caused by myxedema coma for the first time.
Assessing Machine Learning classifiers in COVID-19: The Role of Clinical, Laboratory, and Radiological Features in Predicting Oxygen Saturation
Authors: Shahidzade Mostafa , Jafari Ramezan , Jafari Nematollah Jonaidi , Salmanizadegan Fateme , Teymouri Omid , Sabouri Maryam , Yargholi Mahya , Mollaahmadipour Zahra
Published: September 2024

Background
Oxygen saturation is vital for evaluating COVID-19 severity in hospitalized patients, with levels below 90% indicating respiratory distress and a potential need for intensive care.
Objective
This study develops machine learning models that integrate CT-based features with clinical and laboratory data to predict binary oxygen saturation outcomes in COVID-19 patients.
Method
A retrospective study of 1008 COVID-19 patients admitted between October 2020 and May 2021, using 70% of data for training and 30% for testing. Classifiers used: Linear SVM, SVM with RBF kernels, Logistic Regression, Random Forests, Naïve Bayes, and XGBoost. Performance assessed by validation AUC and 10-fold cross-validation AUC range. Significant features identified by the top validation AUC classifier, prioritizing the top three with importance and stability scores over 0.7.
Results
Linear ML classifiers performed well in Clinical and Laboratory Models, while non-linear classifiers excelled in CT-Based and Integrated Models. Logistic Regression in the Clinical Model achieved an AUC of 0.82, with Age, Gender, and Fever as significant features. In the Laboratory Model, Linear SVM (0.82) identified White Blood Cell count as key. Random Forest in the CT-Based Model (0.87) highlighted Mean Lesion Volume. The Integrated Model's top classifier, SVM with RBF Kernel (0.89), found WBC and Mean NLLV critical.
Conclusion
Linear classifiers effectively predict oxygen saturation using clinical and laboratory data, while non-linear classifiers excel with CT-based and integrated models, highlighting the need for tailored machine learning approaches to different data types in COVID-19 patient care.
Tryptophan and HTP supplementation in the treatment of cognitive and mood disorders: A systematic review and meta-analysis
Authors: Adekunle Hakeem , Balogun Olalekan
Published: September 2024

Introduction:Cognitive and mood disorders, which are increasingly prevalent due to stress, depression, and anxiety, necessitate effective treatments with minimal side effects. Tryptophan (TRP) and 5-hydroxytryptophan (5-HTP), serotonin precursors, are potential therapeutic options. Serotonin deficiency is linked to various cognitive and mood disorders. Previous studies on TRP and 5-HTP supplementation have shown mixed results, suggesting the need for a comprehensive review.
Method: A systematic review and meta-analysis were conducted following PRISMA guidelines, with studies sourced from PubMed, Scopus, and Google Scholar between 2000 and 2023. Only randomized controlled trials (RCTs) involving adults and children with cognitive or mood disorders were included. The exclusion criteriawere studies focused on specific disorders, those involving other mental disorders, or those not in English. The data extracted focused on demographic information, supplement dosage, and outcome measures such as plasma glucose levels, BMI, depression status, and mood.
Results: Sixteen RCTs met the inclusion criteria. Meta-analysis revealed that TRP and 5-HTP supplementation significantly increased total plasma levels and improved mood and depression scores. However, no significant impact was found on BMI or Mini-Mental State Examination (MMSE) score. High heterogeneity was observed across studies.
Conclusion: TRP and 5-HTP supplementation appear to effectively enhance mood and reduce depression symptoms in individuals with cognitive and mood disorders. However, the benefits on cognitive function are less clear, and further research is needed to confirm these findings and explore the variability in responses.
The Development of Process Flow Sheet for Froth Flotation Method of Coal Deposit in The Case of Yayo Area, South-Western Ethiopia
Authors: Yimer Dagnaw , Meseret Getahun
Published: September 2024

Coal is a mixture of organic and inorganic materials and has the ability to burn easily. The objective of this research was to develop a froth flotation flow sheet for the Yayo coal deposit using METSIM simulation software. In this study, the flotation flow sheet for the Yayo coal deposit was created by conducting proximate analysis value and ultimate analysis value. The particle sizes examined were 500μm, 250μm, 125μm, and 63 μm. Based on the particle size distribution, it was found that the 125μm particle size was most suitable for producing high- quality coal with a high percentage yield, as determined by the METSIM simulation software. The proximate analysis values obtained through the simulation software indicated that the moisture content of the coal was 21.25%, the volatile matter content was 22.3%, and the ash content was 6.42%. The average values of the ultimate analysis revealed that the coal contained 62.022% carbon, 4.558% hydrogen, 27.1653% oxygen, and 12.87% sulfur, as determined by the METSIM software simulation. Moreover, the carbon content result obtained from the METSIM simulation software was 79.49%, indicating that the coal in the study area is classified as bituminous coal, which is known for its relatively high carbon content.
Why should a bioengineering lab have engineers and health professionals?
Authors: Santiago Orlando , H. R. da Cunha Thiago , G. Lacerda Rodrigo , Akemi Fujito Elizabeth , L. Ferreira Marcus Vinicius , Huebner Rudolf , L. P. Silva Claudio
Published: September 2024

Through the description of the methodology of the development of a bite force measurement device it will be shown how interdisciplinary work of Engineers and Health Professionals bring enhance of life quality to general population. Bite force measurement is a reliable exam to check stomatognathic system (SS) conditions. In order to provide a reliable, low cost and do-it-yourself gnathodynamometer a Dentist joined Bioengineering Laboratory (LabBio) at UFMG. The development of a 3D printed resin structure was made using CAD/CAM and tested by means of FEM. A Carbon Nano Tube (CNT) extensometer developed at CTNANO at UFMG to capture the structure deformation were fixed in two geometries that showed good results in FEM simulation and will be tested in an EMIC universal mechanical testing machine (DL1000) equipped with a 1 kN load cell. The electrical response of the extensometers was monitored using a Keithley 2000 digital multimeter (Tektronix), connected to a computer and remotely controlled by a LabView application (View Point Systems), a data storage protocol in a SD card and in the clouds using IoT and an data acquisition system will be tested. In bench tests both geometries showed good results with deformation capturable from 40 N. Data was codified using an Arduino Nano and a program was developed for data acquisition and storage. The interdisciplinary work generates prototypes with promising results in bench tests. The fruit of the team work may generate a toll that improves life quality of population by allowing more people to be tested and lowering health costs.
Low-level laser therapy parameters in the treatment of Orofacial pain in temporomandibular disorder
Authors: De Abreu Chaves Maria Emília , Goulart Fonseca Mônica , Beatriz Ferreira Aline
Published: September 2024

Temporomandibular disorder (TMD) comprises a group of dysfunctions of the masticatory system involving joint, myofascial, and even sensory alterations. The main symptom of TMD is orofacial pain, which has a negative impact on the quality of life of TMD sufferers, affecting their productivity at work and school, the quality of their sleep, their appetite, and their satisfaction with life. An alternative for the treatment of TMD is the low-level laser therapy (LLLT), which stimulates cellular functions and promotes therapeutic effects. However, there is no consensus in the literature. Objective: This review aimed to elucidate the parameters of low-level laser therapy in the treatment of orofacial pain in patients with temporomandibular disorder. Methods: A search was carried out for scientific articles published between 2013 and 2023 in the MEDLINE, PEDro, LILACS and SciELO databases. Results: A total of 21 studies were previously selected and after the eligibility criteria, 10 studies were included. Can be suggest a protocol for treating patients with temporomandibular disorder by low-level laser therapy with the following parameters: infrared wavelength, energy density less than 10 J/cm2, output power from 100 to 250 mW and at least 8 sessions of treatment. Conclusion: The low-level laser therapy improves orofacial pain in patients with temporomandibular disorder.
Evaluation and design of a bite force measuring load cell
Authors: Santos Rodrigues Pedro Ivo , Santiago Orlando , Huebner Rudolf
Published: September 2024

The measurement of bite force can be essential for assessing oral health and the functioning of the stomatognathic system. However, its use in dental offices is limited due to operational complexities and costs. This study focused on evaluating the mechanical strength of the user-friendly and low manufacturing cost load cell under development within LABBIO – Bioengineering Laboratory at UFMG, the gnathodynamometer, tailored for children. 3D modeling in SolidWorks and Finite Element Method (FEM) structural analysis were employed to ensure its ability to withstand the desired 1000 N load. Initially, the device did not meet the desired load, resulting in iterations to modify its geometry. After iterations including the replacement of the initial material with a more suitable alternative, removal of edges, and other adjustments, a final prototype meeting mechanical strength and functionality requirements was developed.
Exploring additive manufacturing in assistive technologies to transform the educational experience: empowering inclusion
Authors: Domingos Dias Wellingtânia , Soares Jefferson Henrique , Corrêa Guimarães Lara , Espinosa Martínez Natalia , Ramos Luz Taciana , da Costa Soares Sousa Lima Yaçana Maria , Huebner Rudolf
Published: September 2024

This study explores additive manufacturing's potential in creating tailored assistive technologies, fostering inclusion in education. To design ergonomic solutions for diverse user needs, promoting inclusion and autonomy. A sequential approach involves assessment, 3D modeling, additive manufacturing, and aligning with the Inclusion Support and Accessibility Promotion Program (PIPA). Various assistive technologies were developed, addressing specific needs. The “Ergonomic Pen and Pencil Reamer” improves grip accuracy, and the “Folding Handle for Folding Cup” offers an ergonomic solution. The “Guideline Ruler” supports music education, with accessories like the “Template for Clefs and Musical Notes” and “Thimble with Support Base for Musical Instrument Strings” enhancing versatility. The “Ring with Front Support” aids art education, and the “Support for Scissors” promotes independence. These innovations contribute to inclusion and autonomy. The research underscores the importance of additive manufacturing in crafting personalized solutions, propelling inclusion in education and daily activities. Identified challenges, including material selection and adaptation to diverse needs, signal areas for future research. Continuous collaboration with end-users and professionals remains crucial for enhancing usability and effectiveness, reinforcing the commitment to promoting inclusion and autonomy.
Exploring the impacts of daytime sleepiness on gait, physical balance, and the occurrence of orofacial trauma: a narrative review
Authors: Domingos Dias Wellingtânia , Espinosa Martínez Natalia , Huebner Rudolf , Serra Negra Junia Maria
Published: September 2024

Daytime sleepiness (DS) often accompanies obstructive sleep apnea (OSA), exacerbating its effects. DS can impair cognitive function, attention, reaction time, and motor coordination, increasing the risk of accidents. This study aimed to explore the relationship between DS, changes in gait and balance, and the occurrence of orofacial fractures. A narrative review was conducted using PubMed, Scopus, and Web of Science publications. The analysis revealed the impact of DS and OSA on gait and balance control in older individuals, emphasizing the need for interventions to address these issues and identify associated pathologies. Continuous Positive Airway Pressure (CPAP) therapy was recognized as a potential treatment, although further research is needed to understand DS triggers and treatment options in older populations. The study underscores the importance of analyzing interactions between the central nervous system, medications, balance, and mobility to prevent falls and related injuries. While the literature highlights the vulnerability of elderly individuals and those with OSA to falls, no established link between DS, gait, balance, and orofacial trauma necessitating medical and dental intervention was found. Thus, further research is warranted to address this gap and promote better understanding and management of these conditions.
Treatment of unilateral posterior crossbite with Maurício Vaz de Lima appliance – case report
Authors: Medau Valéria , De Oliveira Cunha Nayara Nery , Navarro Patrícia Braga , De Almeida Junior Luciano Aparecido , Tortelli Ana Paula Cunha
Published: September 2024

Posterior crossbite (PCB) is a common malocclusion and its diagnosis must be careful, because only knowing its etiology can determine the treatment plan. The PCB can be dental, skeletal or functional. For each subtype, there is a specific treatment. The aim of this study was to report the treatment of two patients with Skeletal Unilateral Posterior Crossbite. The patients were treated with the same device, a Maurício expander with a Hawley arch. The technique employed, following the Knowledge of Jaw Functional Orthopedics (JFO), proved to be extremely efficient, allowing correction of crossbite malocclusion, mandible centralization, correct dental positioning, restoring conditions so that the growth and development of the patients occurred in a correct and balanced way.
Contributions of jaw functional orthopedics in temporomandibular joint ankylosis (TMA) – clinical case report
Authors: Duran Ivonne , Cano Adrimar , Gil Paola
Published: September 2024

Temporomandibular joint (TMJ) ankylosis is one of the most disabling pathological conditions that can occur in the maxillofacial region, often occurring at an early age, limiting growth and causing facial deformity, which significantly affects the quality of life of the individual. The objective of the study was to evaluate the contribution of Jaw Functional Orthopedics (JFO) in TMJ ankylosis after the surgical phase. The case of a 7-year-old female patient diagnosed with bilateral condylar ankylosis (fibrous ankylosis on the right side and bony ankylosis on the left side) is presented. On clinical examination, facial asymmetry, retrognathia, muscle contraction and opening limitation were observed. Treatment consisted of temporalis muscle flap rotation surgery with condylectomy and coronoidectomy, physical therapy, and functional therapy with OFM. The clinical results at 4 months of follow-up suggest significant progress in oral opening and protrusion. The patient showed a high degree of satisfaction with the results obtained. She is currently continuing with the use of orthopedic appliances to correct the sequelae of ankylosis and improve mandibular kinematics.
Development of an articulated concrete armor unit against high waves and uneven slopes
Authors: Lee Wan Hoon , Lee Yeosub , Jang Changhwan
Published: September 2024

In this study, a new articulated concrete armor unit named Couple-Lock, which can be enlarged in size to cope with high waves, is easy to secure binding force between units, and can be applied to various field conditions, was developed. The Couple-Lock consists of two symmetrical blocks. One symmetrical block has four legs installed in all directions on one end of the body. Since two left-right symmetrical blocks are connected with a wire rope and behave, a pair of blocks can be treated as a single block and enabling large size to cope with high waves. Also, the Couple-Lock responds flexibly to topographical changes. In order to examine the hydraulic performance and stability of the developed armor unit, a hydraulic model experiment was conducted. As a result, the average reflection coefficients of ordinary wave and storm wave conditions were calculated as 0.433 and 0.533, respectively. The average transmission coefficients under ordinary wave and storm wave conditions were calculated as 0.046 and 0.147, respectively. Among the 62 storm wave conditions, wave overtopping occurred in 50 storm waves. The stability factor of the Couple-Lock was calculated to be about 18, which is twice of the stability factor of the tetrapod.
Fault diagnosis of planetary roller screw mechanism with a lightweight model based on federated learning
Authors: Niu Maodong , Ma Shangjun , Huang Qiangqiang , Deng Pan
Published: September 2024

The fault data for Planetary Roller Screw Mechanisms (PRSM) is challenging to collect in real industrial settings due to the complex nature of practical operations and the lengthy accumulation period. Consequently, there has been little research on PRSM fault diagnosis. Additionally, the high processing cost of PRSM means that institutions are reluctant to make their fault data publicly available, creating a data barrier and further hindering research of the study on fault diagnosis of PRSM. To address these issues, Federated Learning (FL) is applied for PRSM fault diagnosis. In the FL framework, data remains in local storage, preserving data privacy. To reduce transmission costs, a lightweight model called SResNet18 is proposed. SResNet18 reduces parameters by 95.07 % and 61.93 % compared to ResNet18 and DSResNet18, respectively, which decreases the time needed for parameter uploading, model aggregation, and parameter returning. Additionally, SResNet18 has lower computational complexity, with 92.09 % and 36.66 % fewer FLOPs than ResNet18 and DSResNet18, respectively. Healthy and fault data of PRSM are collected on the PRSM testing rig, and the proposed method is evaluated. Results show that our method achieves the highest accuracy of 99.17 %, improving model performance while maintaining data privacy. The proposed SResNet18 also alleviates overfitting and reduces training time in the FL framework.
Research on ACMD-ICYCBD method for rolling bearing fault feature extraction
Authors: Dai Yuanjun , Tan Anwen , Shi Kunju
Published: September 2024

Aiming at the difficulty in obtaining the eigenfrequency of the vibration component of rolling bearing faults in a strong background noise environment and the problem of extraction efficiency, the adaptive chirp mode decomposition (ACMD) combined with Improved maximum second-order cyclostationary blind deconvolution (ICYCBD) fault feature extraction algorithm is proposed. Firstly, to improve the signal-to-noise ratio, the original signal is adaptively decomposed using the ACMD method, and the optimal components are selected based on the principle of maximizing the correlation gini coefficient index. Secondly, to improve the accuracy of parameter setting and extraction efficiency, an improved CYCBD method is proposed to estimate the cyclic frequency set of CYCBD using the proposed enhanced energy harmonic product spectrum (EEHPS) method for the optimal components, the envelope spectrum peak factor index is improved by proposing the envelope spectral period pulse factor (EPPF) index, and the filtering length of the CYCBD is selected adaptively using the step search to obtain the optimized filtered signal. Finally, the envelope spectrum analysis is carried out to extract the fault information accurately. The simulation signals and experimental data show that the method can quickly and accurately extract the fault characteristics of rolling bearings under strong background noise, and the comparison with other methods shows the effectiveness and superiority of the proposed method.
Generalised Poisson-new linear-exponential distribution
Authors: Sah Binod Kumar , Sahani Suresh Kumar
Published: September 2024

It is a compound discrete probability distribution which has two parameters and whose particular case is Poisson-New Linear-Exponential Distribution (PNLED) [1]. The statistical characteristics required for this distribution such as probability mass function (pmf), statistical moments, estimation of parameters and goodness of fit have been derived and explained nicely. To test theoretical reliability of this distribution, goodness of fit has been applied to some over-dispersed data which were used by other researchers and further, we found that this distribution looks more appropriate for statistical modelling than PNLED, generalised Poisson-Lindley distribution (GPLD) [1, 2] and Poisson-Lindley distribution (PLD) [3].
Poor parenting patterns in patients with mental behavioral disorders due to stimulant use
Authors: Aryani Luh Nyoman Alit , Harianja Sahat Hamonangan , Prasetyo Adrian
Published: September 2024

A 23-year-old male was admitted to Ngoerah Hospital with a chief complaint is not being able to sleep began 3 days ago. Sometimes laughs and is expressive during history taking. His complaints of not being able to sleep started 3 days ago when he stopped using methamphetamine because he felt he was getting methamphetamine of low quality. He is nauseous, vomiting has body aches, has no appetite, and is drowsy but has difficulty sleeping. Physical examination is within normal limits. The patient wants to stop using methamphetamine. He has been using methamphetamine since junior high school in 2018, he got to know methamphetamine from junior high school friends. The patient wanted to stop because he felt traumatized by the negative effects of his latest use of methamphetamine. The patient's father is a civil servant and his mother is a midwife at Wangaya Regional Hospital. The patient experiences mental disorders in the form of mental and behavioral disorders due to the use of other stimulants including caffeine. This disorder is caused by the interaction of various factors, resulting in psychiatric symptoms—psychological factors from parenting factors. Father is said to be a strict person.
Modeling cognitive and non-cognitive factors that influence students' reading achievement in Saudi Arabia: A structural equation modeling analysis of PISA (2018)
Authors:   Department of Statistics, King Abdulaziz University, Jeddah, Saudi Arabia, Naji Ayah Ahmed , Altaf Bothinah ,   Department of Statistics, King Abdulaziz University, Jeddah, Saudi Arabia, Alkhouli Abeer ,   Department of Statistics, King Abdulaziz University, Jeddah, Saudi Arabia
Published: September 2024

Reading is essential at all educational levels. This study explores factors influencing reading achievement among Saudi students, using structural equation modeling (SEM) based on PISA 2018 data. It examines whether students' perceptions of teacher support enhance reading skills by promoting self-efficacy and a sense of belonging. Results show that perceived teacher support does not directly affect reading interest (p-value = 0.868). However, self-efficacy and a sense of belonging fully mediate the relationship between teacher support and reading interest. Positive correlations were found between teacher support, self-efficacy, a sense of belonging, and reading ability (p-value = 0.001). This research offers insights into Saudi Arabia's educational context and can inform future studies in similar educational systems.
Ukrainian guidelines for the prevention and treatment of glucocorticoid-induced osteoporosis
Authors: Grygorieva N.V. , Kovalenko V.M. , Коrzh М.О. , Tronko M.D. , Golovach I.Yu. , Dedukh N.V. , Rekalov D.G. , Strafun S.S. , Smiyan S.I. , Golubovska O.A. , Dziublyk Ya.O. , Kharchenko N.V. , Protsenko G.O. , Garmish O.O. , Orlenko V.L. , Klymovytsky F.V. , Musiіenko А.S. , Karasevska T.A.
Published: September 2024

Introduction. Glucocorticoid-induced osteoporosis (GIOP) is a bone metabolic disease that develops as a result of glucocorticoid (GC) use, is one of the most frequent causes of secondary osteoporosis, leads to an increase in the risk of low-energy fractures, disability and mortality of GC users. Despite the few stu­dies conducted in Ukraine on the epidemiology and treatment of GIOP, there have been no national recommendations for its ma­nagement until now, which has become the background for their creation. The purpose was to develop national guidelines for the diagnosis, prevention, and treatment of GIOP based on the analytical analysis of modern literary sources to improve the awareness of the medical community of Ukraine, improve management, and reduce the socio-economic burden of the disease. Materials and ­methods. A group of 18 experts, leading Ukrainian scientists in various fields, was created to develop the guideline. An analysis of current literary sources on epidemiology, risk factors, diagnosis, prevention and treatment of GIOP, and monitoring of the effectiveness and safety of its treatment was carried out. Evidence was synthesized ­using the GRADE system, and a critical assessment of the quality of the recommendations was carried out using the AGREE II tool. ­Results. The guideline consists of 12 provisions on screening, diagnosis, prevention, and treatment of GIOP. The authors emphasized the need to increase the awareness of the medical community of Ukraine regarding the problem, as well as patients regarding the possible side effects of GC. They presented the features of the clinical assessment of the osteoporotic fracture risk in GC users, as well as modern and available in Ukraine methods of diagnosis and treatment of GIOP. Conclusion. The first Ukrainian guideline for screening, diagnosis, prevention, and treatment of GIOP is an important national tool for its management, which is recommended by the Board of the Ukrainian Association of Osteoporosis for use in practical health care by doctors of various specialties.
Biomapping and Enviromapping of Microbial Indicators and Pathogens in a Commercial Beef Processing Facility
Authors: Portillo-Alarcon Rodrigo M. , Brashears Mindy M. , Sanchez-Plata Marcos X. , Roldan Ariana , Miller Markus F.
Published: September 2024

The study aimed to perform biomapping and enviromapping of microbial indicators and pathogens to track microbial changes on carcasses and various surfaces throughout the facility, from harvest to fabrication. Additionally, the study sought to evaluate the effectiveness of interventions and food safety programs in 3 distinct areas of the facility. Samples were collected on 2 separate days to track the fabrication of carcasses from cattle harvested the previous day. On the first day, samples were taken from the lairage area and the harvest floor. On the second day, samples were collected from the fabrication floor. The surfaces tested included walls, equipment, handrails, drains, conveyor belts, cutting boards, and carcasses. MicroTally® cloths (FREMONTA), EZ Reach™ sponges (World Bioproducts), and boot covers (VWR® Basic Protection Anti-Skid Shoe cover, Avantor) were used to collect samples depending on the surface. Most samples, except those from the lairage area, were enumerated using the TEMPO® system (bioMérieux). All samples were tested for pathogens using the BAX® System (Hygiena). The microbial indicators for this study were aerobic counts, Enterobacteriaceae, and Escherichia coli Biotype I, and for pathogens were Escherichia coli O157:H7 (Shiga toxin-producing Escherichia coli [STEC] O157), non-O157 STEC (O26, O45, O103, O111, O121, and O145), and Salmonella spp. As anticipated, statistical reductions among different areas occurred for all 3 locations (P<0.05). The results showed a trend of decreasing microbial loads, starting with high levels of indicators and gradually reducing in the later stages of the process. Salmonella and STEC were detected in the lairage and harvest areas, with some also found on surfaces in the fabrication area before the final interventions were applied. Biomapping and enviromapping are valuable tools for assessing the efficacy of interventions and the effectiveness of food safety programs, enabling manufacturers to make data-driven decisions.
The Future of Performance Management: Shifting from Annual Reviews to Continuous Feedback
Authors: Verma Rohit , Mishra Siddhant
Published: September 2024

Abstract: The landscape of performance management is undergoing a significant transformation, moving away from the traditional model of annual reviews toward a more dynamic and continuous feedback approach. This shift is driven by the need to adapt to the rapidly changing work environment, where agility, employee engagement, and real-time performance improvement are becoming increasingly critical. This chapter explores the evolution of performance management, examining the limitations of annual reviews and the growing demand for more frequent, constructive feedback mechanisms. Continuous feedback not only fosters a culture of ongoing development but also aligns employee objectives with organizational goals in realtime, enhancing overall productivity and job satisfaction. The discussion highlights the technological advancements, such as performance management software and AI-driven analytics, that are enabling this shift, making it easier for organizations to implement and sustain continuous feedback systems. Additionally, the chapter delves into the challenges and considerations that come with this transition, including the need for managerial training, the potential for feedback overload, and the importance of maintaining a balanced approach that supports both individual growth and team collaboration. Through a combination of theoretical insights and practical case studies, this chapter provides a comprehensive overview of the future of performance management, offering actionable strategies for organizations looking to foster a more responsive and employee-centric work culture. The move toward continuous feedback represents not just a trend but a fundamental rethinking of how performance is managed, with the potential to significantly enhance both individual and organizational success in the modern workplace
Cash Conversion Cycle, Asset Turnover, Capital Expenditure and Firm Value: The Mediating Role of Profitability
Authors: Sofian Suriawinata Iman , Tri Budiyani Elin , Gusliana Mais Rimi , Anhar Muhammad
Published: September 2024

Purpose: To examine the impact of the cash conversion cycle, asset turnover, and capital expenditure on firm value, using profitability as the mediating factor.
Methodology/approach: Using a sample consisting of 61 non-cyclical consumer goods listed firms in Indonesia from 2016 to 2021, a structural equation modeling is employed to analyze the direct, indirect, and total effects of the vari-ables being studied on firm value.
Findings: The cash conversion cycle does not have signi-ficant direct or total effects on firm value, but it has a negative and significant indirect effect on firm value through profitability. Asset turnover and capital expen-ditures directly significantly affect firm value in different directions, but they both have positive and significant total effects on firm value. Profitability fully mediates the effect of the cash conversion cycle on firm value, and partially mediates the effect of capital expenditures on firm value.
Practical implications: To ensure value creation, firms are suggested to monitor the cash conversion cycle, enhance asset turnover, and ensure the profitability of capital expenditures.
Originality/value: Providing empirical evidence on the mediating role of profitability in analyzing the effect of the cash conversion cycle, asset turnover, and capital expenditures on firm value.
Efek Moderasi Karakteristik Ceo Perusahaan Mendunia Pada Hubungan Kualitas Informasi Akuntansi Dan Nilai Perusahaan
Authors: Muthmainnah  , Diantimala Yossi , Riha Dedi Priantana
Published: September 2024

Purpose: This study aims to examine whether CEO characteristics strengthen the effect of financial statement information quality on the firm value of well-known global companies.
Methodology/approach: The sample is 366 well-known globally non-financial companies listed on the Asia Pacific Stock Exchange in 2019-2021. The sample was selected using a purposive sampling technique with criteria that companies’ annual and financial reports can be freely accessed. The analysis technique used is panel data regression analysis.
Findings: The results show that the timeliness of financial reports and timely loss recognition significantly affect firm value. However, the effect of earnings management on firm value is not significant. Furthermore, CEO tenure, CEO gender, and CEO accounting education affect firm value significantly. This study contributes to the literature regarding the moderating effect of CEO characteristics in strengthening the effect of accounting information quality on firm value. Then it provides a view of the crucial effect of CEO characteristics in strengthening the impact of accounting information quality on a company's value.
Practical Implication: Companies must pay attention to the financial report information and CEO characteristics such as CEO tenure, CEO gender, and CEO educational background in order to increase company value.
Originality/value: This research is the first that examines the moderating effect of CEO characteristics on the impact of accounting information quality on the firm value of well-known global companies on the Asia Pacific Stock Exchange
Peran Mediasi Manajemen Laba Diantara Struktur Modal Dan Kinerja Keuangan
Authors: Amah Nik , Taufiq Abd. Rohman , Diyanto Adhelia Oktavian Putri
Published: September 2024

Purpose: This study aims to analyze the effect of capital structure on financial performance mediated by earnings management.
Methodology/approach: The research method used is a quantitative approach with secondary data. Samples were taken using purposive sampling to obtain 22 food and beverage subsector companies registered on the IDX during the 2017-2021 period. So, the total observations data is 110. The research analysis techniques using path analysis consist of statistic-t test and sobel test.
Findings: The results showed that capital structure has a significant negative effect on financial performance, capital structure has no effect on earnings management, earnings management has no effect on financial performance, and earnings management cannot mediate between capital structure and financial performance.
Practical implications: If the company's debt is getting higher, it will cause a real decrease in financial performance. However, agent financing originating from the capital structure can prevent earnings management actions so that these actions do not sufficiently affect financial performance.
Originality/value: There are still limited research references regarding capital structure on financial performance mediated by earnings management. This research develops previous research by exploring earnings management with modified Jones measurements in the mediation model.
Optimalisasi Nilai Perusahaan Melalui Moderasi Peran Good Corporate Governance
Authors: Hanun Nur Ravita , Hanif Aisha , Ningrum Surya
Published: September 2024

Purpose: This study aims to determine the role of GCG in moderating the effect of CSR Disclosure, Profitability and Intellectual Capital on Company Value.
Methodology/approach: The number of samples in this study was 87 samples determined by the purposive sampling method. Data analysis techniques using Partial Least Square (PLS) software.
Findings: The results showed that Intelectual Capital has no effect on company value, while CSR disclosure and profitability affect company value. In addition, the results of moderation tests show that GCG cannot moderate the effect of CSR disclosure, profitability and IC on company value.
Practical implications: The basic chemical industry carries out social responsibility to the community by expressing Corporate Social Responsibility. Stakeholders tend to appreciate companies that pay more attention to social responsibility so as to produce a good image and increase profitability.
Originality/value: The novelty of this research is about the object of research in basic industry and chemistry. It also adds the Intelectual Capital variable as an independent variable.
Intelligent Automation Of Fraud Detection And Investigation:A Bibliometric Analysis Approach
Authors: Mahya Lummatul , Tarjo Tarjo , Sanusi Zuraidah Mohd , Kurniawan Fitri Ahmad
Published: September 2024

Purpose:This study aims to examine the use of intelligent automation in the process of detecting and investigating fraud.
Methodology/approach:This research is a bibliometric-based systematic literature review (SLR) related to fraud detection. The research sample consisted of 75 articles obtained from the Science Direct, Emerald Insight, IEE, and MDPI databases for the period 2020–2023.
Findings: The results of the research show that machine learning and deep learning are the most popular fraud detection techniques used by researchers, and the field of credit card fraud is the most popular field used as a research object. The fields of property insurance, health, cyber phishing, taxation, Shell companies, social programs, Ponzi schemes, and supply chain management are the ones that have the least amount of research, namely only one article for each of these fields.
Practical implications: The result show that there are smart tools in detecting fraud in several fields, but it has not been explained whether the existence of these tools can reduce fraud.
Originality/value: This research provides novelty in the use of intelligent automation in the process of detecting and investigating fraud.
Internal Control As A Mediator Of Audit Quality
Authors: Lisa Oyong , Muawanah Umi , Heriyadi Heriyadi , Dahlan Ahmad
Published: September 2024

Purpose: The aim of this research is to analyze the influence of internal control on audit quality, examine the impact of integrity on internal control, investigate the effect of time budget pressure on internal control, assess the influence of integrity on audit quality through internal control, and explore the impact of time budget pressure on audit quality through internal control
Methodology/approach: This study adopts an explanatory research approach, which aims to explain the relationships between the variables under investigation. The research sample consists of 72 auditors working in Public Accounting Firms in Surabaya, selected through purposive sampling based on predefined criteria. Primary data was collected using questionnaires distributed through the Google Form platform. After data collection, the analysis was conducted using the Smart PLS method, a statistical analysis approach used to test the structural model and relationships between research variables.
Findings: The results of this study confirm that internal control has a significant impact on audit quality. Integrity significantly influences internal control, and time budget pressure also has a significant impact on internal control. Internal control acts as a mediator, explaining the influence of integrity on audit quality, as well as the effect of time budget pressure on audit quality
Practical implications: The practical implications of this research encompass auditor training, audit planning, enhancement of internal controls, risk assessment, communication, continuous improvement, reporting, and future research directions in the field of auditing. These implications can be utilized by practitioners, audit firms, organizations, and researchers to elevate audit quality and foster ethical and effective audit practices.
Originality/value: The originality and value of this research lies in a comprehensive examination of various factors in the context of auditing, particularly focusing on integrity, time budget pressures, internal controls, and their collective impact on audit quality. This in-depth analysis provides valuable insights for practitioners and researchers in the auditing field, offering practical implications for improving audit quality and promoting ethical auditing practices. In addition, this study introduces a mediation model that illustrates how internal control mediates the influence of integrity and time budget pressure on audit quality, contributing to a deeper understanding of the mechanisms underlying this relationship. Overall, the study's comprehensive approach, methodological rigor, and insightful findings contribute to advancing knowledge in auditing and providing actionable recommendations to improve auditing practice and results.
Locus Of Control Memoderasiwhistleblowing System, Literasi Keuangan, Dan Tindakan Audit Terhadap Kualitas Laporan Keuangan
Authors: Dian Aditya D. Aditya , Baridwan Zaki , Mardiati Endang
Published: September 2024

Purpose:
Knowing the effect of whistleblowing system, financial literacy, and audit actions on the quality of the company's financial statements moderated by the locus of control.
Methodology/approach:
This type of research is quantitative. Researchers collected data by providing questionnaires to financial employees of tobacco companies in East Java. The Data were analyzed using descriptive analysis test, classical assumption test, hypothesis test, and coefficient of determination test.
Findings:
This study found that wishtlebowing system, financial literacy, and partial audit actions have a positive and significant effect on the quality of the financial statements of tobacco companies in East Java. As for locus of control can moderate whistleblowing system on the quality of financial statements, locus of control can not moderate financial literacy on the quality of financial statements, and locus of control can weaken the audit action on the quality of financial statements.
Practical implications:
Later a company management can be helped by the existence of this study in using the strategy and establish rules for the progress of the company related to the quality of financial statements.
Originality/value:
The novelty of this study on the location of research, moderation variables, and independent variables.