bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of a nomogram for prediction of postoperative sore throat in patients under general anaesthesia: a single-centre, prospective, observational study
Authors: Jiang Jingjing , Wang Zhonghan , Xu Qiancheng , Chen Qun , Lu Weihua
Published: May 2022

Objectives

Postoperative sore throat (POST) is very common in patients under general anaesthesia. However, there is no effective clinical predictive model for reducing its occurrence. The objective of this study was to estimate the risk factors for POST in patients after general anaesthesia by designing a nomogram.

Design

A prospective study.

Setting

This study was conducted in a large tertiary hospital.

Participants

Patients aged 18–85 years old who received general anaesthesia with either an endotracheal tube or supraglottic airway and of American Society of Anesthesiologists classification level Ⅰ–III.

Results

A total of 442 patients were enrolled in this study, with a POST incidence of 44.1%. The results showed that younger age (≤55 years), surgical site (head and neck surgery), duration of anaesthesia (≥4 hours) and history of chronic pharyngitis were independent risk factors for POST in general anaesthesia patients. Receiver operating characteristic (ROC) curves and calibration curves were used to evaluate the nomogram. The area under the ROC curve was 0.784 and the C-index was 0.779.

Conclusion

A nomogram combining age, surgical site, duration of anaesthesia and history of chronic pharyngitis is potentially useful in predicting POST under general anaesthesia.

Trial registration number

ChiCTR-ROC-17013258; Post-results.
Feasibility of decentralised, task-shifted hepatitis C testing and treatment services in urban Myanmar: implications for scale-up
Authors: Draper Bridget Louise , Yee Win Lei , Shilton Sonjelle , Bowring Anna , Htay Hla , Nwe Nwe , Markby Jessica , Kyi Khin Pyone , Easterbrook Philippa , Naing Win , Win Thin Mar , Aung Khin Sanda , Howell Jessica , Pedrana Alisa , Hellard Margaret
Published: May 2022

Objectives

To assess the feasibility considerations for a decentralised, one-stop-shop model of care implemented in Yangon, Myanmar.

Setting

Two primary care level clinics in urban Yangon, Myanmar.

Design

This is a feasibility study of a highly effective care model. Using Intervention Complexity Framework by Gericke et al, we collated and analysed programmatic data and evaluation data to outline key project implementation requirements and experiences.

Participants

Programmatic data were collected from clinical records, GeneXpert device test and maintenance reports, national guidelines, product and device instructions and site monitoring visit reports. Healthcare providers involved in delivering care model contributed interview data.

Results

The main feasibility considerations are appropriate storage for test kits and treatments (in response to temperature and humidity requirements), installation of a continuous stable electricity supply for the GeneXpert device, air-conditioning for the laboratory room hosting GeneXpert, access to a laboratory for pretreatment assessments and clear referral pathways for specialist consultation when required. Lessons from our project implementation experiences included the extensive time requirements for patient education, the importance of regular error monitoring and stock storage reviews and that flexible appointment scheduling and robust reminder system likely contributed to high retention in care.

Conclusions

Detailed documentation and dissemination of feasibility requirements and implementation considerations is vital to assist others to successfully implement a similar model of care elsewhere. We provide 10 recommendations for successful implementation.

Trial registration number

The trial was registered at ClinicalTrials.gov NCT03939013 on May 6, 2019. This manuscript presents post-results data on feasibility.
Peer-led family-centred problem management plus for immigrants (PMP-I) for mental health promotion among immigrants in USA: protocol for a pilot, randomised controlled feasibility trial
Authors: Poudel-Tandukar Kalpana , Jacelon Cynthia S , Martell Christopher R , Poudel Krishna C , Rai Shan , Ramdam Razu , Laws Holly , Meyer Jerrold S , Bertone-Johnson Elizabeth R , Hollon Steven D
Published: May 2022

Introduction

Research is needed to investigate preventive strategies to reduce mental health burden and assess effective implementation among immigrants. Problem management plus (PMP) is a low-intensity multicomponent psychological intervention developed by the World Health Organization (WHO) that trained laypeople can deliver. PMP has been adapted as a prevention intervention and developed as PMP for immigrants (PMP-I), including psychoeducation, problem-solving, behavioural activations and mind–body exercise, to address immigrants’ multiple stressors. This pilot trial aims to assess the feasibility and acceptability of PMP-I and provide a preliminary estimate of the difference between PMP-I versus community support services pamphlets on the primary outcomes of interest (stress, anxiety and depressive symptoms) to inform the design of a large-scale intervention.

Methods and analysis

The feasibility and acceptability of PMP-I will be assessed by measuring recruitment, session attendance, retention rates, programme acceptability and the fidelity of intervention delivery. This pilot trial will test preliminary effects of PMP-I vs community support services pamphlets in a randomised controlled trial (N=232 participants from 116 families (2 members/family); 58 families randomised to condition intervention or control) on stress, anxiety and depressive symptoms (primary outcomes), chronic physiological stress assessed in hair cortisol (secondary outcomes), and coping, family conflict resolution, and social networking (targets), with assessment at baseline, postintervention and 3-month postintervention. Eligibility criteria for the primary study participants include Bhutanese ≥18 years resettled in Massachusetts with a score of ≤14 on the Patient Health Questionnaire-9. All family members will be invited to participate in the family-based intervention (one session/week for 5 weeks). Multilevel modelling will compare the longitudinal change in outcomes for each treatment arm.

Ethics and dissemination

The Institutional Review Board of the University of Massachusetts Amherst approved this study (Protocol: 1837). Written informed consent will be obtained from all participants. The study results will be used to inform the design of a large-scale intervention and will be disseminated in peer-reviewed journals and conferences.

Trial registration number

NCT04453709.
Understanding e-cigarette content and promotion on YouTube through machine learning
Authors: Kong Grace , Schott Alex Sebastian , Lee Juhan , Dashtian Hassan , Murthy Dhiraj
Published: May 2022

Introduction

YouTube is a popular social media used by youth and has electronic cigarette (e-cigarette) content. We used machine learning to identify the content of e-cigarette videos, featured e-cigarette products, video uploaders, and marketing and sales of e-cigarette products.

Methods

We identified e-cigarette content using 18 search terms (eg, e-cig) using fictitious youth viewer profiles and predicted four models using the metadata as the input to supervised machine learning: (1) video themes, (2) featured e-cigarette products, (3) channel type (ie, video uploaders) and (4) discount/sales. We assessed the association between engagement data and the four models.

Results

3830 English videos were included in the supervised machine learning. The most common video theme was ‘product review’ (48.9%), followed by ‘instruction’ (eg, ‘how to’ use/modify e-cigarettes; 17.3%); diverse e-cigarette products were featured; ‘vape enthusiasts’ most frequently posted e-cigarette videos (54.0%), followed by retailers (20.3%); 43.2% of videos had discount/sales of e-cigarettes; and the most common sales strategy was external links for purchasing (34.1%). ‘Vape trick’ was the least common theme but had the highest engagement (eg, >2 million views). ‘Cannabis’ (53.9%) and ‘instruction’ (49.9%) themes were more likely to have external links for purchasing (p<0.001). The four models achieved an F1 score (a measure of model accuracy) of up to 0.87.

Discussion

Our findings indicate that on YouTube videos accessible to youth, a variety of e-cigarette products are featured through diverse videos themes, with discount/sales. The findings highlight the need to regulate the promotion of e-cigarettes on social media platforms.
How mounds are made matters: seismic line restoration techniques affect peat physical and chemical properties throughout the peat profile
Authors: Kleinke Kimberly , Davidson Scott J. , Schmidt Megan , Xu Bin , Strack Maria
Published: May 2022

Seismic lines are prominent linear disturbances across boreal Canada with large-scale consequences to wildlife and ecosystem function. Although seismic line restoration has been observed to improve tree growth and survival, application in peatlands has been shown to alter ecosystem functions such as hydrology and carbon storage. The most common active restoration method is called mechanical mounding, where the classic technique inverts the peat profile. New mounding methods that maintain the peat profile may provide benefits by preserving existing vegetation and reducing disturbance. To determine the effects of different mounding methods on soil quality, we collected and analyzed peat cores from two different sites for various soil properties (C/N ratios, δ13C, δ15N, and Fourier transform infrared (FTIR) spectroscopy humification indices). Vegetation surveys were also conducted. The two sites are both a collection of seismic lines crossing poor fens in Alberta. One site was treated with the classic method, while the other was treated with two new mounding methods. Classic mechanical mounding significantly increased the degree of decomposition, indicative of lower substrate quality. Mechanical mounding also greatly reduced moss cover and introduced large amounts of bare ground cover. The two newer mounding methods did not result in these changes and were largely comparable to natural peat properties and vegetation communities. Preserving the peat profile in new mounding methods may support faster return of ecosystem function.
Abscisic acid application regulates vascular integrity and calcium allocation within apple fruits
Authors: Angmo Tashi , Rehman Munib Ur , Mir Mohammad Maqbool , Bhat Barkat Hussain , Bhat Sajad Ahmad , Kosser Safina , Ahad Shabnam , Sharma Anil
Published: May 2022

Calcium is a very poorly translocated nutrient in the flesh of apple fruits with the advancement of growth. Within the fruit, movement is further restricted toward distal portion relative to proximal. Even numerous foliar applications of calcium do not always achieve the desired effect. Thus, the objective of this study was to enhance the calcium allocation in distal parts of apple fruit in response to whole plant application of abscisic acid (ABA). Five-year-old apple plants of Super Chief Sandidge on M9 were treated with ABA at 400 ppm, calcium chloride at 0.4% and water (Control) at four stages (30, 65, 100, and 135 days after full bloom (DAFB)), and then analyzed for xylem functionality and calcium allocation in leaf and various fruit tissues at 10 days after each treatment, i.e., S1—40, S2—75, S3—110, and S4—45 DAFB. The results obtained showed that xylem functionality started impairing just after S2; consequently, the calcium allocation was also reduced in middle and calyx portions of fruit after that stage. However, xylem functionality was significantly retained (up to 30%) in ABA-treated fruits at S4 stage, which in other treatments was found to be nil at the calyx end of the fruit. This retention of xylem tissue functionality enhanced allocation of calcium from roots in middle and calyx end of the apple fruit. Leaf calcium was reduced with ABA applications. With the enhancement of calcium in the fruits, increases in soluble solid content and titratable acidity were observed at maturity.
Characterization and expression of the Pirin gene family in Triticum aestivum
Authors: Brunetti Sabrina C. , Arseneault Michelle K.M. , Gulick Patrick J.
Published: May 2022

Pirins are nuclear bicupin proteins, encoded by genes that are one of several gene families that comprise the cupin superfamily in plants. Pirin genes have been implicated in stress response pathways studied in Arabidopsis and At- Pirin1 has been shown to interact with the heterotrimeric G-protein alpha subunit (GPA1). The aim of this study was to identify the members of the Pirin gene family in Triticum aestivum, to correct their annotations in the whole genome, and gain an insight into their tissue-specific expression as well as their response to abiotic and biotic stresses. The Pirin gene family in T. aestivum is comprised of 18 genes that represent six paralogous gene copies, each having an A, B, and D homeolog. Expression analysis of the Pirin genes in T. aestivum Illumina RNA-seq libraries, which included sampling from differing tissue types as well as abiotic and biotic stresses, indicates that the members of the Pirin gene family have specialized expression and play a role in stress responses. Pirin gene families are also identified in other monocots including Aegilops tauschii, Hordeum vulgare, Brachypodium distachyon, Oryza sativa, Zea mays, Sorghum bicolor, and the dicot Arabidopsis thaliana.
Spectroscopic parameters and electromagnetic form factor of kaon in vacuum and a dense medium
Authors: Er N. , Azizi K.
Published: May 2022

The spectroscopic parameters as well as electromagnetic form factor of the strange particle kaon are investigated in vacuum and a medium with finite density. The obtained vacuum mass and decay constant, which are consistent with the existing experimental results, are used to extract the $$ Q^2 $$

Q
2

dependence of the kaon electromagnetic form factor in the interval $$Q^2\in [0,10]$$

Q
2

∈

[
0
,
10
]

 GeV$$^2$$

2

in vacuum. The obtained results at lower and intermediate values of $$ Q^2 $$

Q
2

are consistent with the existing experimental data within the presented uncertainties. The $$ Q^2 $$

Q
2

behavior of the electromagnetic form factor of kaon in vacuum and in the interval $$Q^2\in [0,6]$$

Q
2

∈

[
0
,
6
]

 GeV$$^2$$

2

is in a nice agreement with the existing predictions of the Lattice QCD and the solution of the Bethe–Salpeter equation for the model of Nambu and Jona-Lasinio (NJL) with proper-time regularization, as well. The obtained vacuum radius for kaon is also in a nice agreement with the world’s average experimental result. We extend the analyses to a medium with higher densities and obtain the behavior of the mass, decay constant, electromagnetic form factor and radius with respect to density. The obtained results for some of the parameters are compared with the existing predictions of other models and approaches. The results obtained in the present study can be useful for future experimental and theoretical studies both in vacuum and a dense medium.
Neutron stars in mimetic gravity
Authors: Noshad Hajar , Hendi Seyed Hossein , Panah Behzad Eslam
Published: May 2022

In this paper, a modified version of the hydrostatic equilibrium equation based on the mimetic gravity in the presence of perfect fluid is revisited. By using the different known equation of states, the structural properties of neutron stars are investigated in general relativity and mimetic gravity. Comparing the obtained results, we show that, unlike general relativity, we can find the appropriate equation of states that support observational data in the context of mimetic gravity. We also find that the results of relativistic mean-field-based models of the equation of states are in better agreement with observational data than non-relativistic models.
Remarks on the black hole shadows in Kerr-de Sitter space times
Authors: Omwoyo Eunice , Belich Humberto , Fabris Júlio C. , Velten Hermano
Published: May 2022

This work is geared towards analysis of shadows cast by Kerr-de Sitter (KdS) and Kerr-de Sitter Revisited (RKdS) black holes. Considering observers in the vicinity of the static radius, we derive the impact parameters defining the apparent positions of the shadows. Such observers are of interest to our work because embedding diagrams have shown that de Sitter space-time is analogous to an asymptotically flat one in the vicinity of the static radius. We also perform a comparative analysis between our result with that in Ref. [1]. Furthermore, we numerically obtain the radii of curvature, vertical diameters and horizontal diameters of the shadows. We find that for $$\Lambda =1.11\times 10^{-52} \,\, m^{-2}$$

Λ
=
1.11
×

10

-
52

m

-
2

, M87* observations cannot distinguish a RKdS black hole shadow from that of a Kerr black hole. Additionally, for the same value of $$\Lambda $$
Λ
, KdS and RKdS black hole shadows are, in practise, indistinguishable. Previously, it has also been shown that when $$\Lambda =1.11\times 10^{-52} \,\, {\text {m}}^{-2}$$

Λ
=
1.11
×

10

-
52

m

-
2

, KdS and Kerr black hole shadows are indistinguishable. Utilizing the 2017 EHT observations of M87* on the allowed range of the characteristic radius of the shadow, we obtain constraints on both black holes. When, $$a/M>0.812311$$

a
/
M
>
0.812311

, we observe that large angles of inclination ($$\theta >30.5107^{\circ }$$

θ
>
30
.

5107
∘

) do not pass the constraints for both KdS and RKdS black holes.
Tsallis holographic dark energy reconsidered
Authors: Dheepika M. , Mathew Titus K
Published: May 2022

We consider the interacting Tsallis Holographic Dark Energy (THDE), with the Granda–Oliveros (GO) scale as the infrared (IR) cutoff, as dynamical vacuum. We analytically solved for the Hubble parameter, in a spatially flat FLRW universe with dark energy and matter as components, and the solution traces the evolutionary path from the prior decelerated to the late accelerated epoch. Without interaction, the model predicts a$$\varLambda $$ΛCDM like behavior with an effective cosmological constant. We used Pantheon Supernovae type Ia, observational Hubble data (OHD), cosmic microwave background (CMB), and baryon acoustic oscillation (BAO) data to constrain the free parameters of the model. The estimated values of the cosmological parameters were consistent with observational results. We analyzed the behavior of the model using the statefinder and$$\omega ^\prime _{e}-\omega _{e}$$ωe′-ωeplane where$$\omega _{e}$$ωeand$$\omega ^\prime _{e}$$ωe′corresponds to the effective equation of state and its evolution, respectively. The model shows a quintessence behavior in general, and the model trajectory ends in a point that corresponds to the de Sitter phase. We performed a dynamical analysis of the model, concluding that the prior decelerated and late accelerated phases are unstable and stable equilibria, respectively. We also investigated the thermodynamical nature of the model and found that the generalized second law remains valid in the dynamical vacuum treatment of the model.
Deeper Understanding of the Lithiation Reaction during the Synthesis of LiNiO2 Towards an Increased Production Throughput
Authors: Kurzhals Philipp , Riewald Felix , Bianchini Matteo , Ahmed Shamail , Kern Andreas Michael , Walther Felix , Sommer Heino , Volz Kerstin , Janek Jürgen
Published: May 2022

Efficient manufacturing of cathode active materials (CAMs) for Li-ion batteries is one key target on the roadmap towards cost reduction and improved sustainability. This work deals with a two-stage calcination process for the synthesis of LiNiO2 (LNO) consisting of a (partial) lithiation step at moderate temperatures and short dwell times and a subsequent high temperature crystallization to decouple the chemical reactions and crystal growth. The use of an agitated-bed lithiation using the rotational movement of a rotary kiln setup shows beneficial effects compared to its fixed-bed counterpart in a crucible as the lithiation reaction is faster under otherwise comparable conditions. The temperature profile for the agitated-bed process was further optimized to avoid the presence of needle-like LiOH residuals in the intermediate product indicative of an incomplete reaction. The partially-lithiated samples were subjected to a second calcination step at a maximum calcination temperature of 700 °C and afterwards revealed comparable physico-chemical properties and electrochemical behavior compared to a reference sample made by a standard one-stage calcination. In a simplified model calculation, the proposed calcination concept leads to an increase in throughput by a factor of ∼ 3 and thus could embody an important lever for the efficiency of future CAM production.
Perspectives on Technical Challenges and Scaling Considerations for Tubular Protonic-Ceramic Electrolysis Cells and Stacks
Authors: Kee Robert J. , Ricote Sandrine , Zhu Huayang , Braun Robert J. , Carins George , Persky Joshua E.
Published: May 2022

Proton-conducting ceramics (protonic ceramics) form the basis for applications that include intermediate-temperature (e.g., 500 °C–700 °C) fuel cells, electrolyzers, and membrane reactors. The electrolyte membranes are typically perovskites such as heterovalently doped barium cerates and zirconates (e.g., BaCe1−x−yZrxYyO3−δ, BCZY; and BaCe1−x−y−zZrxYyYbzO3−δ, BCZYYb). Although the materials are dominantly proton conductors, they are mixed ionic-electronic conductors (MIEC) with oxygen-ion and small-polaron mobility. The present paper is concerned primarily with steam-electrolysis applications with the reactors using tubular cell configurations. An important advantage of the protonic-ceramic cells is that they can produce nearly dry hydrogen. Each tubular cell is comprised of a negatrode (electrolysis cathode), proton-conducting electrolyte membrane, and a positrode (electrolysis anode). The tubular cells are typically supported on the relatively thick (order of one millimeter) composite negatrode, with thin (order tens of microns) external membrane and positrode layers. The paper explores considerations for scaling from laboratory-based demonstrations to deployable technology.
Insights into Highly-Efficient CO2 Electroreduction to CO on Supported Gold Nanoparticles in an Alkaline Gas-Phase Electrolyzer
Authors: Gu Yueyuan , Wei Jucai , Wang Luyang , Wu Xu
Published: May 2022

Electrochemical conversion of CO2 to fuels powered by renewable energy is an attractive technology for carbon emission reduction and renewable energy utilization elevation. Here, electrochemical reduction of CO2 to selectively produce CO using a homemade electrolyzer and Au nanocatalyst was investigated. Au nanoparticles were uniformly anchored on N-doped carbon to improve catalytic activity, and the C/N ratio and operating temperature were adjusted to elevate catalytic selectivity. The resulting Au catalyst exhibited a current efficiency for CO production higher than 90% in a wide full cell voltage range (1.8 ∼ 3.0 V), a high mass activity of 900 A gAu
−1, and a total current density of 200 mA cm−2 under 3.0 V cell voltage at room temperature. A scale-up 3 × 3 cm CO2 electrolyzer was constructed and tested at 1 A, the current efficiency for CO production reached 93% but decreased within a few hours due to the potassium carbonate precipitation phenomenon at the cathode. The important influence of an unideal ion transport pathway during electrolysis on CO2 electrolyzer performance was revealed, and its stability can be greatly improved by using deionized water instead of KOH solution.
Recovery of Degraded Ni-Rich NMC811 Particles for Lithium-Ion Batteries
Authors: Yu Han , Gao Yan , Kirtley James , Borgmeyer Gabriel , He Xiaoqing , Liang Xinhua
Published: May 2022

Nickel-rich cathode materials attract a lot of attention due to their high energy density. However, their sensitivity to air and moisture hinders their practical applications. Exposing Ni-rich NMC in the air will produce by-products that are not conducive to lithium-ion transmission. Water washing can be used to remove by-products on the surface, but it can also introduce new problems, such as the generation of NiO on the particle surface, which will reduce the electrochemical performance of the material. In this study, Al2O3 atomic layer deposition (ALD) was applied on degraded NMC811 particles to recover the electrochemical performance of the degraded NMC811 particles, which had been exposed to moisture. XPS and XRD analysis verified that the Al2O3 ALD coating removed the contaminant components on the particle surface, such as LiOH and Li2CO3, as well as reactivation of inactive Ni due to reaction with moisture. Furthermore, the coating film can also inhibit side reactions during the charge and discharge process and enhance the cycling stability.
Polyoxovanadate-Activated Carbon-Based Hybrid Materials for High-Performance Electrochemical Capacitors
Authors: Vannathan A. A. , Chandewar P. R. , Shee D. , Mal S. S.
Published: May 2022

Two different polyoxovanadates derivatives, K5MnIVV11O32.10 H2O (MnV11) and K7MnIVV13O38.18 H2O (MnV13), have been studied to evaluate their electrochemical performance. These polyoxovanadates were deposited on activated carbon (AC) to prepare AC-MnV11 and AC-MnV13 composites. The electrochemical performance of the AC- MnV11 electrode exhibits the remarkable specific capacitance of 479.73 F g−1 at a current density of 0.6 A g−1, along with incredible specific power and energy of 960 W kg−1. Likewise, the AC-MnV13 exhibits a specific capacitance of 357.33 F g−1 at the current density of 0.6 A g−1 with a specific energy of 71.46 Wh kg−1. Interestingly, the AC- MnV11 could light up the red and yellow color LED bulbs for a duration of 80 and 60 s, respectively, indicating a considerable specific power of the material. The AC-MnV13 electrode shows significantly less lighting up during the 65 and 30 s period with red and yellow LED bulbs.
Clinical Analysis of Approach Selection of Extraction of Maxillary Embedded Mesiodens in Children
Authors: Kong Jie , Peng Zhaowei , Zhong Tianhang , Shu Huang , Wang Ji , Kuang Yiyuan , Ding Guicong
Published: May 2022

Objective. To analyze the relationship between the position of embedded mesiodens in maxilla and surgical approach in children and thus provide reference materials for surgical design. Methods. According to the preoperative cone-beam computed tomography (CBCT) examination, the location and surgical approach characteristics of 625 children aged 4-16 years old who presented with embedded mesiodens in maxilla and were diagnosed in our department from January 2016 to December 2021 were statistically analyzed. Results. There were 877 embedded mesiodens in 625 children. The selected cases were classified according to the axial angle relationship between mesiodens and adjacent normal teeth or tooth germs, including 84 cases of acute angle type (including the same direction) (13.4%), 66 cases of vertical type (10.6%), 114 cases of obtuse angle type (18.2%), 271 cases of inverted type (43.4%), and 90 cases of mixed type (14.4%). The palatal gingival margin approach was the most selected surgical approach for the cases of acute angle (including synclastic), obtuse angle, and inverted type, and the palatal gingival margin approach and the combined labial-palatal approach were the most selected surgical approach for the cases of vertical and mixed type. Conclusion. Palatal gingival margin approach was the most common surgical approach for various types of embedded mesiodens in maxilla in children. Surgeons should classify the case of mesiodens according to the preoperative imaging examination and design the surgical approach reasonably.
Application Research of Cross‐Border Logistics Based on Cloud Distribution Model
Authors: Zang Shengli , Wang Lihong , Li Suqin
Published: May 2022

Cross‐border logistics is an important support for the rapid development of cross‐border e‐commerce. This paper expounds cross‐border e‐commerce and its development status and explores the problems existing in cross‐border e‐commerce logistics distribution, such as high cost, low level of information, e‐commerce credit evaluation system being not perfect, and professional personnel shortage. Advanced cloud distribution mode is introduced into cross‐border e‐commerce logistics, and cloud logistics distribution network model is built using the precise center‐of‐gravity method. Based on the cloud distribution, the paper puts forward some suggestions for the development of cross‐border logistics, such as optimizing the path to reduce transshipment links, optimizing the level of logistics informatization, improving the market supervision system and credit evaluation mechanism, and improving the talent training mechanism, in order to improve the stability and security of cross‐border logistics distribution, reduce logistics costs, and improve service quality.
Effect of Time to Detection on the Measured Concentrations of Blood Proteins Associated with Alzheimer’s Disease
Authors: Chen Hsin-Hsien , Ho Chia-Shin , Hsu Ming-Hung , Lin Yu-Chen , Chang Jui-Feng , Yang Shieh-Yueh
Published: May 2022

Background: For assays using immunomagnetic reduction, a reagent composed of antibody-functionalized magnetic nanoparticles is dispersed in phosphate-buffered saline solution. The real-time signals of alternating-current (ac) magnetic susceptibility, χac, of the reagent are subsequently recorded after mixing the reagent with a biofluid sample. After mixing the reagent and sample, the reduction in χac of the mixture is calculated and used to quantify the concentration of the target biomarker in the sample. The reduction does not occur immediately but rather occurs at some time after mixing. This observation implies that the time elapsed before recording the real-time signals of χac of a reagent-sample mixture needs to be investigated to ensure that the signals are fully recorded. In this work, the effect of time to detection on the measured concentrations of proteins in human plasma after mixing the reagent and sample is examined. Methods: The proteins analyzed are related to Alzheimer’s disease: amyloid β 1–40, amyloid β 1–42, and Tau protein. The investigated times to detection after the mixing the reagent and sample are 0, 20, 30, 40, and 120 min. Results: The results show that the recording of real-time signals of χac should be conducted within 20 min after mixing the reagent and sample.
A Case of Overlapping Clinical Features of Idiopathic Granulomatous Mastitis, Hidradenitis Suppurativa, and Pyoderma Gangrenosum Successfully Treated with Adalimumab
Authors: Breznik Vesna , Marko Pij Bogomir
Published: May 2022

A 36-year-old woman with a 6-month history of painful unilateral mammary nodules and abscesses was initially treated by gynecologists under the diagnosis of idiopathic granulomatous mastitis (IGM). IGM is an entity that has not been described in classical dermatological textbooks and is considered a rare inflammatory breast disease assumingly associated with trauma, infection, or autoimmune system manifestations. In this patient, the lesions were refractory to conventional treatment of IGM comprising of surgical incisions, systemic antibiotics, dexamethasone, and methotrexate. At the initial visit to the dermatology department, a working diagnosis of localized hidradenitis suppurativa (HS) of breast was established, and treatment with systemic doxycycline was initiated. After the diagnostic incisional biopsy, the inflamed nodule deteriorated into a painful ulceration, implying a pathergy phenomenon. Histopathological features were consistent with the granulomatous type of pyoderma gangrenosum (PG). Treatment with systemic methylprednisolone and mycophenolate mofetil was unsuccessful. Subsequently, the patient developed nodules in the inguinal and axillary areas, typical for HS. Finally, adalimumab treatment resulted in the complete resolution of all lesions without relapse even after the biologic therapy was discontinued. Although in this case, IGM was not confirmed histopathologically, we noted several etiopathological and therapeutic similarities between IGM, PG, and HS and summarized them in a unique table. Further observations are needed to ascertain the potential associations among the three entities.
Insatisfação e complicações pós-cirúrgicas caracterizam erro médico?
Authors: Pavão Douglas Mello , Werneck Fernando Carneiro , Faria José Leonardo Rocha de , Titonelli Victor Elias , Albuquerque Rodrigo Sattamini Pires e , Sousa Eduardo Branco de
Published: May 2022

Nota-se atualmente um crescente número de processos judiciais a médicos, com base em uma suposta quebra de contrato ao direito do consumidor, onde se exige do profissional médico resultados, enquanto este, pelo código de ética médica e bom senso, tem obrigação de meios. O objetivo deste estudo foi discutir os resultados, satisfação e complicações de três das principais cirurgias ortopédicas à nível do joelho (área de atuação dos autores) com o fim de estabelecer diferenças entre erro e insucesso, próprio do ato médico. Concluímos que a imperfeição faz parte da natureza humana e que, por diversos motivos, as cirurgias ortopédicas complicam, falham e pacientes ficam insatisfeitos, independente do grau de recursos que o profissional disponha, o que não caracteriza erro médico.
Contribuições das concepções ético-filosóficas de Confúcio para o desenvolvimento ético do naturólogo
Authors: Corrêa Camila de Godoi , Leite-Mor Ana Cláudia Moraes Barros
Published: May 2022

Introdução: O presente trabalho propõe discutir a conduta e a responsabilidade ética e social do naturólogo, enquanto profissional de saúde, a partir do estudo da obra Os Analectos, de Confúcio. Objetivos: Desenvolver reflexões éticas com base no pensamento de Confúcio, apresentando seu modelo ético de humano/pessoa como uma proposta para a reflexão ética do naturólogo. Métodos: Foi realizada uma pesquisa teórico-reflexiva com metodologia experiencial-hermenêutica do livro Os Analectos, de Confúcio, e o fichamento e a sistematização de literaturas para a contextualização histórico-social dessa mesma obra. A metodologia experiencial-hermenêutica se deu pela leitura pausada, capítulo a capítulo, de três traduções do livro simultaneamente, e da vivência reflexiva dos ensinamentos do clássico no dia a dia, juntamente com a discussão destes em grupo de pesquisa. Resultados e discussão: Os resultados foram apresentados em duas instâncias: as que correspondem à qualificação de si mesmo através do aprendizado e do desenvolvimento das virtudes, e as referentes ao aprimoramento na relação com os outros, como o ensino, o governo e a amizade. Estes aspectos são refletidos na conduta profissional ética do naturólogo, além de levantar a reflexão sobre a responsabilidade social deste profissional. Considerações finais: Consideramos as reflexões éticas de Confúcio, a sua proposta de aprendizado, desenvolvimento, valorização da vida e aposta positiva na humanidade de extrema valia para o aprimoramento ético do naturólogo, bem como para o melhor exercício da medicina chinesa, a partir do que se pode compreender mais profundamente a perspectiva da qual ela emerge.
Complex Surgical Management of Radiation-Associated Left Retroperitoneal Sarcoma
Authors: Walker Jasmine C. , Bradley Joel F. , Luckenbaugh Amy N. , Lambright Eric S. , Sandvall Brinkley K. , Keedy Vicki L. , Holt Ginger E. , Tan Marcus C. B.
Published: May 2022

Radiation-associated sarcomas (RASs) are rare entities that tend to have an aggressive course and poor prognosis. Criteria for diagnosis of radiation-associated sarcoma include therapeutic radiation preceding the development of sarcoma, sarcoma arising within or near the irradiated field, and tumor histology that is distinct from the primary tumor necessitating radiation. Despite their relatively uncommon occurrence, RASs are a well-established complication of radiation therapy. We present the complex, multidisciplinary surgical management of a patient with multi-compartmental radiation-associated sarcoma of the left retroperitoneum occurring nearly 25 years after undergoing whole trunk radiation for Hodgkin’s lymphoma.
Resection of Intracochlear Schwannomas With Immediate Cochlear Implantation
Authors: Patel Tirth R. , Fleischer Lindsay , Wiet R. Mark , Michaelides Elias M.
Published: May 2022

Introduction:

Intralabyrinthine schwannomas, including the intracochlear variety, are rare benign tumors. They can cause a number of symptoms and have the potential to grow to involve other critical structures of the inner ear and skull base. While surgical resection is feasible, there is typically permanent hearing dysfunction as a result of resection and subsequent fibrosis. Here, we present 2 cases of intracochlear schwannomas (ICS) that were successfully resected with simultaneous cochlear implant placement.

Methods:

Patient 1 presented with an intravestibulocochlear schwannoma. This patient underwent a translabyrinthine approach. Endoscopic assistance was used to dissect the tumor from the vestibule and basal turn of the cochlea, through an enlarged round window approach. A cochlear implant was placed via a round window cochleostomy. Patient 2 presented with an intracochlear schwannoma involving the basal and middle turns of the cochlea. The patient underwent a trans-otic approach for resection. A large portion of the cochlear promontory required unroofing for complete exposure of the tumor. A cochlear implant was then placed via a round window cochleostomy.

Results:

Upon cochlear implant activation, Patient 1’s sound field thresholds using the implant were near the normal range of hearing, ranging from 25 to 50 dB HL from 250 to 6000 Hz. Patient 2’s 6-month post-operative cochlear implant sound field testing ranged from 20 to 30 dB HL from 250 to 6000 Hz and speech recognition testing revealed 59% on AZ Bio sentences compared to 0% pre-operatively.

Conclusion:

Simultaneous cochlear implantation after resection of intracochlear schwannomas is safe and successful in restoring hearing. Attention to adequate exposure and endoscopic assistance, when required, allow for gross total resection while minimizing trauma to cochlear structures. In such cases, immediate cochlear implantation allows for hearing rehabilitation before likely cochlear fibrosis can occur.
The Influence of Physical Burden on the Esthetic Preference for Green Natural Environment
Authors: Liu Sizhe , Wang Hua , Liu Wenxuan , Lai Shuxian , Zhao Xueru , He Xianyou , Zhang Wei
Published: May 2022

The perception of beauty is known to be associated with the bodily sensations and evolutionary implications. However, whether the esthetic preference for natural landscape environments with different evolutionary benefits changes on the basis of different degrees of bodily sensations is still an open issue. The present study used four experiments to address this issue. The results showed that participants wearing a heavy backpack gave higher esthetic scores to and generate a strong attentional bias toward the green natural landscapes. Furthermore, the implicit association test (IAT) revealed that a green natural landscape was more readily associated with a high level of relaxation when the participants wore a backpack. The results indicated that the bodily sensation of a physical burden modulates the esthetic preference for natural environments when they consist of green plants, which are associated with a high level of relaxation and have significant evolutionary implications.
Financial crime scripting: Introducing a financial perspective to the Dutch cocaine trade
Authors: van Santvoord Victor D , van Ruitenburg Teun
Published: May 2022

The Netherlands operates as a distribution hub for cocaine, due to its transit characteristics cocaine is imported from South America and distributed to the rest of Europe. To enhance the financial approach to organized crimes, this article proposes a new crime script: a financial crime script. With a special focus on the importing stage, 76 Dutch court rulings are analyzed to make a first financial crime script. This financial crime script provides new insight into the proceeds, costs, and means of payment of criminal organizations and therefore could aid law enforcement in calculating criminal gains.
Internet-Mediated Joint Construction: Engaging Second Language Learners in Synchronous Online Writing Instruction Through ClassIn
Authors: Wang Di , Huang Yu
Published: May 2022

This article introduces the use of Internet-mediated joint construction (JC) to engage second language (L2) writers to participate in virtual classroom activities in an online teaching environment. Affected by the ongoing COVID-19 pandemic, schools and universities in the People’s Republic of China were required to rapidly transit to remote teaching. The switch from the traditional classroom-based scenarios to the online environment was challenging for teachers. One of the extreme difficulties is to engage students in virtual-class activities. To address this issue, the authors designed an Internet-mediated JC teaching practice and implemented it on ClassIn, an online teaching platform for one semester. Analysis of students’ after-class online surveys and interviews suggested that the Internet-mediated JC practice helped students to build a connected network and thus engaged them in actively interacting with both the teacher and peers in the online environment. Pedagogical implications are discussed to contribute to the teaching practice of L2 online writing instruction.
How can we address the ever-pressing need to ‘green up’ surgical practice in the National Health Service?
Authors: Anastasopoulos Nikolaos-Andreas , Papalois Vassilios
Published: May 2022

Clinical practice has inadvertently changed after the COVID-19 pandemic and currently the need to provide sustainable surgical services is more pressing than ever. The National Health Service has committed to a long-term efficient plan to reduce carbon footprint but there is no detailed plan for surgical practice, the domain that contributes the most to hospital-derived pollution. A series of consecutive steps and measures ought to be taken, starting from a hybrid approach quantifying surgically attributed carbon footprint. Then, a variety of suggested measures can be widely discussed and accordingly applied on a wider or more local level. Appropriate training should always precede implementing new practices to ensure that staff is familiar with these. These measures cover a broad range and should be arranged on a patient-centred basis from preoperative preconditioning to an effective follow-up. The need for more intense research and implementation of enhanced recovery protocols is widely discussed. Also, the necessity of green research and reinvestment of materials and resources is highlighted. A change of philosophy from a cradle-to-grave approach to a repurposing approach is suggested. We are confident that a new era is dawning in surgical practice and teamwork is the key for providing greener surgical services.
Examining the psychometric properties of the ELLECCT: A commentary on Weadman, Serry and Snow (2022)
Authors: Dobinson Keeley L. , Dockrell Julie E.
Published: May 2022

Domain-specific observational tools that use valid and objectively measurable items are key to supporting improvement and developing understanding of practice in early years classrooms. The ‘Emergent Literacy and Language Early Childhood Checklist for Teachers’ (ELLECCT) aims to address a current gap in the tools that are available to capture behaviours which support language and literacy during book reading activities. We examine the ELLECCT’s utility as a single observational tool for both researchers and educators seeking to capture extratextual oral language and emergent literacy strategies during shared book reading.
Chronic Granulomatous Invasive Fungal Sinusitis in Patients With Immunocompetence: A Review
Authors: Rupa Vedantam , Peter Jayanthi , Michael Joy Sarojini , Thomas Meera , Irodi Aparna , Rajshekhar Vedantam
Published: May 2022

Objective

We aimed to study the literature on chronic granulomatous invasive fungal sinusitis to elucidate the changing trends in the management of the disease.

Data Sources

Using specific keywords, we searched the PubMed, PubMed Central, and Scopus databases over the past 50 years, which yielded 938 articles in the English language.

Review Methods

Scrutiny of 147 relevant articles revealed 15 homogenous case series (255 cases of histologically proven chronic granulomatous fungal sinusitis alone) and 8 heterogeneous case series (patients with other types of fungal sinusitis included), which were analyzed in detail (all with >5 cases each).

Conclusions

The disease typically affected middle‐aged adults with immunocompetence. Most reports were from Sudan, India, and Saudi Arabia. A slowly progressive orbital, cheek, or palatal mass with proptosis (88.2%) or sinonasal symptoms (39.2%) was typical. Ethmoid (57.2%) and maxillary (51.4%) sinuses were chiefly affected with intracranial extension in 35.1%. Aspergillus flavus (64%) was the most frequent isolate reported. Endoscopic excision (78.8%) followed by azole therapy was the preferred treatment in recent reports. Orbital exenteration and craniotomy were infrequently performed. Complete resolution or improvement was reported in 91.3% of patients. Mortality ranged from 5.9% to 22.2%. There is a trend in the literature toward less radical and disfiguring surgery and preferential use of azoles, with good outcomes even in advanced cases.

Implications for Practice

Chronic granulomatous fungal sinusitis should be diagnosed on the basis of well‐defined histopathologic features. A combination of endoscopic sinus surgery and azole therapy usually yields good outcomes.
Genetic causal beliefs and developmental context: Parents’ beliefs predict psychologically controlling approaches to parenting
Authors: Nyman Tristin , Stichter Matthew , Rivera Grace N , Maffly-Kipp Joseph , Brooker Rebecca J , Vess Matthew
Published: May 2022

We examined the association of parents’ genetic causal beliefs and parenting behaviors, hypothesizing a positive association between parents’ genetic causal beliefs and their use of psychological control. Study 1 ( N = 394) was a cross-sectional survey and revealed that parents’ genetic essentialism beliefs were positively associated with their self-reported use of harsh psychological control, but only for parents who reported relatively high levels of problem behaviors in their children. Study 2 ( N = 293) employed a 4-day longitudinal design and revealed that parents’ genetic causal beliefs positively predicted the use of psychological control, especially on days when they perceived relatively high problem behaviors in children. Overall, the studies demonstrated that parents’ genetic causal beliefs about character positively predicted psychologically controlling and harsh responses to child problem behaviors, which may ultimately be detrimental to child development.