bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolving Trends in the Management of Duodenal Leaks After Pancreas Transplantation: A Single-Centre Experience
Authors: Ray Samrat , Hobeika Christian , Norgate Andrea , Sawicka Zaneta , Schiff Jeffrey , Sapisochin Gonzalo , McGilvray Ian D. , Selzner Markus , Reichman Trevor W. , Shwaartz Chaya
Published: September 2024

Duodenal leaks (DL) contribute to most graft losses following pancreas transplantation. However, there is a paucity of literature comparing graft preservation approach versus upfront graft pancreatectomy in these patients. We reviewed all pancreas transplants performed in our institution between 2000 and 2020 and identified the recipients developing DL to compare based on their management: percutaneous drainage vs. operative graft preservation vs. upfront pancreatectomy. Of the 595 patients undergoing pancreas transplantation, 74 (12.4%) developed a duodenal leak with a median follow up of 108 months. Forty-five (61%) were managed by graft preservation strategies, with the rest being treated with upfront graft pancreatectomy. DL managed by graft preservation strategies had similar graft survival rates at 1 and 5-year compared to the matched cohort of population without DL (95% and 59% vs. 91% and 62%; p = 0.78). Multivariate analysis identified male recipient (OR: OR: 6.18; CI95%: 1.26–41.09; p = 0.04) to have higher odds of undergoing an upfront graft pancreatectomy. In appropriately selected recipients with DL, graft preservation strategies utilizing either interventional radiology guided percutaneous drainage or laparotomy with/without repair of leak can achieve comparable long-term graft survival rates compared to recipients without DL.
Brain Tumor Detection Using Magnetic Resonance Imaging and Convolutional Neural Networks
Authors: Martínez-Del-Río-Ortega Rafael , Civit-Masot Javier , Luna-Perejón Francisco , Domínguez-Morales Manuel
Published: September 2024

Early and precise detection of brain tumors is critical for improving clinical outcomes and patient quality of life. This research focused on developing an image classifier using convolutional neural networks (CNN) to detect brain tumors in magnetic resonance imaging (MRI). Brain tumors are a significant cause of morbidity and mortality worldwide, with approximately 300,000 new cases diagnosed annually. Magnetic resonance imaging (MRI) offers excellent spatial resolution and soft tissue contrast, making it indispensable for identifying brain abnormalities. However, accurate interpretation of MRI scans remains challenging, due to human subjectivity and variability in tumor appearance. This study employed CNNs, which have demonstrated exceptional performance in medical image analysis, to address these challenges. Various CNN architectures were implemented and evaluated to optimize brain tumor detection. The best model achieved an accuracy of 97.5%, sensitivity of 99.2%, and binary accuracy of 98.2%, surpassing previous studies. These results underscore the potential of deep learning techniques in clinical applications, significantly enhancing diagnostic accuracy and reliability.
Enhancing Fire Safety Knowledge among Underwater Road Tunnel Users: A Survey in China
Authors: Lu Chunling , Liu Dingli , Huang Yao , Li Ying , Chen Shanbin , Liu Weijun , Wang Jingya
Published: September 2024

In recent years, the number of underwater road tunnels in Chinese cities has increased. However, the current situation of personal fire safety literacy as it pertains to these tunnels remains unclear. To address this gap, a questionnaire survey was conducted to investigate people’s awareness of escape slides, evacuation signs, and the correct evacuation paths for fire escape. A total of 1049 respondents in Changsha, China, were surveyed, with 791 valid questionnaires collected and analyzed. The findings revealed that a significant proportion of respondents (81.80%) were unaware of the presence of escape slides in underwater road tunnels, while 87.86% could not recognize them and 93.05% could not use them. Only 42.04% of respondents could identify evacuation signs in underwater road tunnels. In the event of a fire, just half of the respondents could select the appropriate escape or evacuation path. Additionally, demographic differences among respondents also influenced their level of fire safety literacy. Based on these findings, it is recommended that the government and relevant organizations should enhance the dissemination of knowledge regarding escape slides and evacuation signs in underwater road tunnels.
Recent Insights into Roles of Hypoxia-Inducible Factors in Retinal Diseases
Authors: Lee Deokho , Tomita Yohei , Miwa Yukihiro , Kunimi Hiromitsu , Nakai Ayaka , Shoda Chiho , Negishi Kazuno , Kurihara Toshihide
Published: September 2024

Hypoxia-inducible factors (HIFs) are transcriptional factors that function as strong regulators of oxygen homeostasis and cellular metabolisms. The maintenance of cellular oxygen levels is critical as either insufficient or excessive oxygen affects development and physiologic and pathologic conditions. In the eye, retinas have a high metabolic demand for oxygen. Retinal ischemia can cause visual impairment in various sight-threating disorders including age-related macular degeneration, diabetic retinopathy, and some types of glaucoma. Therefore, understanding the potential roles of HIFs in the retina is highly important for managing disease development and progression. This review focuses on the physiologic and pathologic roles of HIFs as regulators of oxygen homeostasis and cellular metabolism in the retina, drawing on recent evidence. Our summary will promote comprehensive approaches to targeting HIFs for therapeutic purposes in retinal diseases.
Exploring Taxonomic and Genetic Relationships in the Pinus mugo Complex Using Genome Skimming Data
Authors: Sikora Joanna , Celiński Konrad
Published: September 2024

Genome skimming is a novel approach that enables obtaining large-scale genomic information based on high-copy DNA fractions from shallow whole-genome sequencing. The simplicity of this method, low analysis costs, and large amounts of generated data have made it widely used in plant research, including species identification, especially in the case of protected or endangered taxa. This task is particularly difficult in the case of closely related taxa. The Pinus mugo complex includes several dozen closely related taxa occurring in the most important mountain ranges in Europe. The taxonomic rank, origin, or distribution of many of these taxa have been debated for years. In this study, we used genome skimming and multilocus DNA barcoding approaches to obtain different sequence data sets and also to determine their genetic diversity and suitability for distinguishing closely related taxa in the Pinus mugo complex. We generated seven different data sets, which were then analyzed using three discrimination methods, i.e., tree based, distance based, and assembling species by automatic partitioning. Genetic diversity among populations and taxa was also investigated using haplotype network analysis and principal coordinate analysis. The proposed data set based on divergence hotspots is even twenty-times more variable than the other analyzed sets and improves the phylogenetic resolution of the Pinus mugo complex. In light of the obtained results, Pinus × rhaetica does not belong to the Pinus mugo complex and should not be identified with either Pinus uliginosa or Pinus rotundata. It seems to represent a fixed hybrid or introgressant between Pinus sylvestris and Pinus mugo. In turn, Pinus mugo and Pinus uncinata apparently played an important role in the origins of Pinus uliginosa and Pinus rotundata.
The Complete Mitochondrial Genome of the Siberian Scoter Melanitta stejnegeri and Its Phylogenetic Relationship in Anseriformes
Authors: Chen Huimin , Chen Yaqin , Wang Zhenqi , Wu Dawei , Chen Pan , Chen Yanhong
Published: September 2024

The Siberian Scoter (Melanitta stejnegeri) is a medium sea duck distinct from M. deglandi due to the absence of hybridization and differences in morphological characteristics. However, knowledge of its phylogenetic relationships within Anseriformes is limited due to a lack of molecular data. In this study, the complete mitogenome of M. stejnegeri was firstly sequenced, then annotated and used to reconstruct the phylogenetic relationships of 76 Anseriformes species. The complete mitogenome of M. stejnegeri is 16,631 bp and encodes 37 typical genes: 13 protein-coding genes, 2 ribosomal RNAs, 22 transfer RNAs, and 1 non-coding control region. Its mitogenome organization is similar to that of other Anseriformes species. The phylogenetic relationships within the genus Melanitta are initially clarified, with M. americana at the base. M. stejnegeri and M. deglandi are sister groups, clustering with M. fusca and M. perspicillata in order. Phylogenetic analysis suggests that Mareca falcata and M. strepera are sister groups, differing from previous studies. Results firstly indicate that Clangula hyemalis and Somateria mollissima are sister groups, suggesting a potentially skewed phylogenetic relationship may have been overlooked in earlier analyses relying solely on mitochondrial genomes. Our results provide new mitogenome data to support further phylogenetic and taxonomic studies of Anseriformes.
Vitexin Mitigates Haloperidol-Induced Orofacial Dyskinesia in Rats through Activation of the Nrf2 Pathway
Authors: Chen Shu-Mei , Wang Mao-Hsien , Chang Kuo-Chi , Fang Chih-Hsiang , Lin Yi-Wen , Tseng Hsiang-Chien
Published: September 2024

Vitexin (VTX), a C-glycosylated flavone found in various medicinal herbs, is known for its antioxidant, anti-inflammatory, and neuroprotective properties. This study investigated the protective effects of VTX against orofacial dyskinesia (OD) in rats, induced by haloperidol (HPD), along with the neuroprotective mechanisms underlying these effects. OD was induced by administering HPD (1 mg/kg i.p.) to rats for 21 days, which led to an increase in the frequency of vacuous chewing movements (VCMs) and tongue protrusion (TP). VTX (10 and 30 mg/kg) was given intraperitoneally 60 min after each HPD injection during the same period. On the 21st day, following assessments of OD, the rats were sacrificed, and nitrosative and oxidative stress, antioxidant capacity, mitochondrial function, neuroinflammation, and apoptosis markers in the striatum were measured. HPD effectively induced OD, while VTX significantly reduced HPD-induced OD, decreased oxidative stress, enhanced antioxidant capacity, prevented mitochondrial dysfunction, and reduced neuroinflammatory and apoptotic markers in the striatum, and the protective effects of VTX on both behavioral and biochemical aspects of HPD-induced OD were significantly reduced when trigonelline (TGN), an inhibitor of the nuclear factor erythroid-2-related factor 2 (Nrf2)-mediated pathway, was administered. These findings suggest that VTX provides neuroprotection against HPD-induced OD, potentially through the Nrf2 pathway, indicating its potential as a therapeutic candidate for the prevention or treatment of tardive dyskinesia (TD) in clinical settings. However, further detailed research is required to confirm these preclinical findings and fully elucidate VTX’s therapeutic potential in human studies.
Changes in Cardiopulmonary Capacity Parameters after Surgery: A Pilot Study Exploring the Link between Heart Function and Knee Surgery
Authors: Segreti Andrea , Fossati Chiara , Monticelli Luigi Maria , Valente Daniele , Polito Dajana , Guerra Emiliano , Zampoli Andrea , Albimonti Giorgio , Zampogna Biagio , Vasta Sebastiano , Papalia Rocco , Antonelli Incalzi Raffaele , Pigozzi Fabio , Grigioni Francesco
Published: September 2024

Background: A knee injury in an athlete leads to periods of forced exercise interruption. Myocardial work (MW) assessed by echocardiographic and cardiopulmonary exercise testing (CPET) are two essential methods for evaluating athletes during the period following injury. However, compared to pre-surgery evaluations, the variations in cardiovascular parameters and functional capacity assessed by these methods after surgery remain unclear. Methods: We evaluated 22 non-professional athletes aged 18–52, involved in prevalently aerobic or alternate aerobic/anaerobic sports activities, who were affected by a knee pathology requiring surgical treatment. The evaluation was performed at rest using transthoracic echocardiography, including MW assessment, and during exercise using CPET. Each athlete underwent the following two evaluations: the first before surgery and the second after surgery (specifically at the end of the deconditioning period). Results: Resting heart rate (HR) increased significantly (from 63.3 ± 10.85 to 71.2 ± 12.52 beats per minute, p = 0.041), while resting diastolic and systolic blood pressure, forced vital capacity, and forced expiratory volume in the first second did not show significant changes. Regarding the echocardiographic data, global longitudinal strain decreased from −18.9 ± 1.8 to −19.3 ± 1.75; however, this reduction was not statistically significant (p = 0.161). However, the global work efficiency (GWE) increased significantly (from 93.0% ± 2.9 to 94.8% ± 2.6, p = 0.006) and global wasted work (GWW) reduced significantly (from 141.4 ± 74.07 to 98.0 ± 50.9, p = 0.007). Additionally, the patients were able to perform maximal CPET at both pre- and post-surgery evaluations, as demonstrated by the peak respiratory exchange ratio and HR. However, the improved myocardial contractility (increased GWE and decreased GWW) observed at rest did not translate into significant changes in exercise parameters, such as peak oxygen consumption and the mean ventilation/carbon dioxide slope. Conclusions: After surgery, the athletes were more deconditioned (as indicated by a higher resting HR) but exhibited better resting myocardial contractility (increased GWE and reduced GWW). Interestingly, no significant changes in exercise capacity parameters, as evaluated by CPET, were found after surgery, suggesting that the improved myocardial contractility was offset by a greater degree of muscular deconditioning.
Physical Function, Self-Perceived Physical Fitness, Falls, Quality of Life and Degree of Disability According to Fear and Risk of Falling in Women with Fibromyalgia
Authors: Denche-Zamorano Ángel , Pereira-Payo Damián , Collado-Mateo Daniel , Adsuar-Sala José Carmelo , Tomas-Carus Pablo , Parraca Jose Alberto
Published: September 2024

Background: People with fibromyalgia (FM) experience a range of symptoms (chronic widespread pain, fatigue, mood disorder, sleep problems, muscle stiffness) that promote deterioration of physical condition and function. With impaired physical function, fear of falling and risk of falling increases. This study evaluated physical function, self-perceived physical fitness, falls, quality of life, and the degree of disability caused by FM according to fear and risk of falling in Spanish adult women with FM. Methods: Cross-sectional study involving 84 Spanish adult women with FM. Participants completed tests to assess their physical function and completed questionnaires to evaluate self-perceived physical fitness, falls, the disabling effect of FM, quality of life, fear of falling, and risk of falling. Nonparametric statistical tests were used to analyze possible intergroup differences (Mann–Whitney U test) and correlations between variables (Spearman’s Rho). Results: Women with a fear of falling and at risk of falling presented a worse performance in physical tests, worse self-perceived physical fitness, greater number of falls, lower quality of life, and greater degree of disability due to FM. Weak and moderate correlations were found for fear of falling and fall risk and the variables of interest. However, no intergroup differences were found, nor significant correlations in all variables. Conclusions: Women with FM who present fear of falling and risk of falling tend to have worse performance in physical function tests, in addition to worse self-perceived physical fitness, higher number of falls, poorer quality of life, and greater disabling effect of FM.
Recurrent Spinal Canal Stenosis after Decompression and Fusion Surgery Due to Bone Overgrowth: Case Report
Authors: Cho Yong-Chan , Kim Dae-Woong , Wang Soon-Do , Kim Chang-Hyun , Hong Chang-Hwa
Published: September 2024

Bone regrowth commonly occurs following lumbar decompression surgery. Although it is rare for neurological symptoms to occur due to bone regrowth, this study describes two patients who underwent both decompression and fusion surgeries but experienced spinal canal restenosisthat was severe enough to induce neurological symptoms. A 32-year-old man underwent posterior decompression and posterior lumbar interbody fusion for lumbar canal stenosis at the L4/L5 level 5 years prior. However, the sudden onset of lower back pain occurred 5 years later. Bone overgrowth on the left side was observed at the L4/L5 level. A second surgery was performed, and the patient’s symptoms improved significantly. In the second case, a 56-year-old man underwent posterior decompression and posterior lumbar fusion at the L3/L4 and L4/L5 levels for an L4 burst fracture. One month later, he complained of lower back pain and underwent a second posterior decompression surgery. One year later, he presented to an outpatient clinic with lower back pain and neurological symptoms. Bone overgrowth was observed on both sides at the L4/L5 level. Thus, screw removal and laminectomy at the L3, L4, and L5 levels were performed as a third surgery. This study discusses the factors affecting bone regrowth and the methods that can be used to prevent it.
Development of a QAMS Analysis Method for Industrial Lanolin Alcohol Based on the Concept of Analytical Quality by Design
Authors: Abudureheman Kaidierya , Wang Qinglin , Zhang Hao , Gong Xingchu
Published: September 2024

The Analytical Quality by Design (AQbD) concept was adopted to establish a quantitative analysis of multi-components with a single marker (QAMS) method for industrial lanolin alcohol, targeting cholesterol, lanosterol, and 24,25-dihydrolanosterol. The potential critical method parameters (CMPs) were identified as column temperature, flow rate, and gradient. Definitive screening design and statistical modeling were employed to optimize the gradient conditions of the mobile phase, column temperature, and flow rate. The Method Operable Design Region (MODR) was determined using a risk-based quantification approach. The robustness was assessed using a Plackett–Burman experimental design, followed by methodological validation. Optimal analytical conditions were as follows: acetonitrile (B)—water (A) mobile phase system; flow rate of 1.58 mL/min; detection wavelength of 205 nm; injection volume of 10 µL; and column temperature of 37 °C. A gradient elution program was implemented as follows: 0–19.0 min, 90.5% B; 19.0–25.0 min, 90.5–100% B; and 25.0–55.0 min, 100% B. Cholesterol served as an internal standard for quantifying lanosterol and 24,25-dihydrolanosterol, with relative correction factors of 0.4227 and 0.8228, respectively. This analytical method utilized only the cholesterol reference substance as an internal standard to quantify the content of cholesterol, lanosterol, and 24,25-dihydrolanosterol in industrial lanolin alcohol. It reduced the testing costs and enhanced efficiency, making it potentially suitable for widespread adoption in lanolin alcohol processing industries.
High-Efficiency Selective Adsorption of Rubidium and Cesium from Simulated Brine Using a Magnesium Ammonium Phosphate Adsorbent
Authors: Liu Haining , Wang Yanping , Zhang Qiongyuan , Han Wenjie , Zhang Huifang , Ye Xiushen
Published: September 2024

Rubidium and cesium are critical strategic elements, and their development and utilization are of great significance. In this study, a magnesium ammonium phosphate (MAP) adsorbent was prepared and characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET) surface area analysis, and Fourier transform infrared spectroscopy (FTIR). The adsorption performance of the adsorbent for Rb+ and Cs+ in solution was investigated. The results showed that the adsorbent exhibited high adsorption capacities of 2.83 mol/g for Rb+ and 4.37 mol/g for Cs+. In simulated brine, the adsorbent demonstrated excellent selectivity for Cs+. Kinetic and thermodynamic studies indicated that the adsorption process followed a pseudo-second order kinetic model and Langmuir isotherm model. The primary adsorption mechanism was an ion exchange. The development of this adsorbent holds significant promise for the extraction of rubidium and cesium from liquid resources.
Kinetic Study and Process Optimization of Plutonium Barrier Units for Enhanced Plutonium Stripping in the PUREX Process
Authors: Zhu Haowei , Chen Qi , Zuo Chen , Li Tianchi , Yuan Jieqiong , Zhao Ziqian , Yan Taihong , Zheng Weifang
Published: September 2024

In the PUREX (the plutonium uranium reduction extraction) process, a plutonium barrier unit (1BXX) is used to achieve deep plutonium stripping. According to the operating experience of the French reprocessing plant, after the separation of uranium and plutonium in the first cycle (1B + 1BXX), the plutonium barrier unit has excellent stripping effect, such that the removal of plutonium from uranium can already be achieved in the first cycle, and the second cycle only needs to focus on the removal of neptunium from uranium in order to obtain a qualified uranium product. In recent decades, China has also been actively conducting research on the plutonium barrier unit process to reduce the plutonium concentration in the primary uranium product in the first cycle to avoid the need to remove neptunium and plutonium at the same time in the second cycle, and to improve the efficiency and feasibility of reprocessing. Due to the lack of design basis for plutonium barriers to achieve deep plutonium stripping at present, this study conducts a basic study on the plutonium barrier unit, aiming to provide data for the optimization of plutonium barriers in the actual reprocessing process at a later date. In this work, a kinetic study on the reduction and stripping of trace plutonium from dibutyl phosphate-containing organic phases was carried out first, and the kinetic equations for the reduction and stripping of Pu(IV) by U(IV) under flow process conditions were obtained. The effects of U(IV) addition on the extraction loss of U(IV) and the concentration distribution of U(IV) at various stages were investigated by process simulation. Additionally, the oxidation of U(IV) under process conditions was investigated to clarify the process chemistry of U(IV) oxidation and to provide a reference for the oxidation consumption of U(IV). Finally, the process parameters of the plutonium barrier unit were preliminarily designed based on the above research.
National rating of scientific and technological development of subjects of the Russian Federation
Authors:   Ministry of Science and Higher Education of the Russian Federation, accredited expert in the scientific and technical field, Ustinovich Elena Stepanovna
Published: September 2024

The scientific interest of Russian researchers in the topic of scientific and technological development of Russia and its regions is due to a number of factors, among which the most important is the rapid development of up-to-date technologies and the unique opportunities they provide to the states of the modern world. This is also a practical necessity for us, determined by the current conditions of the civilizational development of our country in the context of instability of its development, foreign policy turbulence, the need to fight against ill-wishers and outright enemies of Russia during the special military operation, and the fight against international terrorism. However, not only the interest of the Russian scientific community today is able to form an idea of this topic. Practical measures taken within the framework of state management of the scientific and technological development of the country are aimed today at the role of the subjects of the Russian Federation and their contribution to the country's innovative treasury. This is crucial for us, since in the conditions of different economic opportunities of different regions of the country and their asymmetry in socio-economic development, economic division of regions into «donors» and «recipients», features of their economic activity and its nature (raw materials extraction, development of new processing industries, etc.), it is important to understand which of the subjects has accumulated a special scientific and technological potential necessary for a «breakthrough» and in which area of economic activity it is applicable. It is also essential to understand the role of government bodies at the regional level in their contribution to the processes of scientific and technological development of the administered territories. For this purpose, a rating of scientific and technological development of subjects of the Russian Federation has been introduced at the government level, and the criteria necessary for understanding and assessing its condition have been defined.
EDUCAÇÃO AMBIENTAL PATRIMONIAL: UMA REVISÃO ACERCA DE PONTA GROSSA, PARANÁ
Authors: Nascimento Sthephany Larissa , Dalzoto Mazzutti Gabriela , Maris Orth Ritter Antiqueira Lia
Published: September 2024

A Educação Ambiental Patrimonial envolve o processo da compreensão sócio-histórica do Patrimônio Natural, promovendo o ensino sobre a importância da preservação desse ambiente e construindo a valorização da memória local. Visando esses ideais, a presente pesquisa constitui de uma revisão da literatura sobre a relação da prática de Educação Ambiental Patrimonial a partir do Patrimônio Natural da cidade de Ponta Grossa, delimitando como campo duas Unidades de Conservação: Parque Estadual Vila Velha e Parque Nacional dos Campos Gerais, para fomentar a proposta de atividades no âmbito de Ensino não-formal.
ALÉM DO SILÊNCIO: PRIMAVERA SILENCIOSA PARA ABORDAR O USO DE INSETICIDAS NO ENSINO
Authors: Galvão Gabrielle Maria , Isabeli Valentim Mariana , Dalzoto Mazzutti Gabriela , Ferreira Machado Elaine , Orth Ritter Antiqueira Lia Maris
Published: September 2024

O presente artigo destaca a importância da obra Primavera Silenciosa de Rachel Carson como uma peça fundamental na conscientização dos perigos associados aos pesticidas.  Por meio de uma revisão da literatura, pontua-se o aumento significativo do uso de agrotóxicos no Brasil, assim como suas implicações na saúde pública e no meio ambiente. Propõe-se uma sequência didática destinada a explorar o tema agrotóxicos associando a aula ao livro, visando fomentar o engajamento dos alunos na discussão sobre o uso de inseticidas e seus impactos. Além disso, sublinha-se o papel crucial da Educação Ambiental na formação de uma consciência ambiental e na promoção da sustentabilidade.
A HORTA ESCOLAR COMO FERRAMENTA DE EDUCAÇÃO AMBIENTAL NO ENSINO ESPECIALIZADO
Authors: Lopes dos Santos Rezena Pamela Eduarda , Macedo de Lima Daniela , Boemer Cesar Pereira Luciana
Published: September 2024

Apesar dos inúmeros avanços alcançados no decorrer da história da Educação Especial, ainda é preciso reconhecer os obstáculos presentes neste campo. Devido à preocupação em abordar os benefícios trazidos pelo contato com a natureza para pessoas com necessidades especiais, o presente artigo traz uma discussão a respeito da horta como ferramenta de Educação Ambiental atrelada ao ensino especializado. Com base nas discussões levantadas, foi possível pensar em uma Educação Ambiental Inclusiva no contexto da Educação Ambiental, baseada na adaptação de atividades para que todos, independentemente do diagnóstico possam compreender a necessidade de cuidado e proteção com o meio ambiente
CRIANÇAS COM A NATUREZA: EXPERIÊNCIAS NA “CIRANDA DAS HORTALIÇAS DE OUTONO”
Authors: Silva Patrícia de Oliveira Rosa da , Guimarães Martinez Mateus , Pena Gonçalves Murilo , Nunes Maria Eduarda , Uchima Stephany , Vieira Elverson
Published: September 2024

Este relato de experiência aborda a desconexão humana com a natureza e os benefícios da reconexão através de atividades ao ar livre, destacando a "Ciranda das Hortaliças de Outono" (2024), uma proposta de extensão da “Sala Verde Sibipiruna: extensão, pesquisa e educação ambiental” da Universidade Estadual de Londrina. Através de atividades de Metodologias Ativas na perspectiva da Ambientalização, como semeadura, plantio e experiências sensoriais - as Cirandas, 12 crianças, entre seis e dez anos de idade, foram incentivadas a explorar e valorizar o meio natural, utilizando sementes e mudas de hortaliças orgânicas. Ao longo das atividades, foi possível vivenciar a importância das plantas em um espaço promissor de horticultura.
IMPLANTAÇÃO DE UMA HORTA MEDICINAL EM AMBIENTE ESCOLAR: UMA PROPOSTA DE EDUCAÇÃO AMBIENTAL EM UMA ESCOLA DE SURDOS DE FOZ DO IGUAÇU/PR
Authors: Oliveira Letícia Silva de , Pacheco Roseli Bernardete Dahlem , Souza Angela Maria de , Graciano Luciana
Published: September 2024

A implantação de uma horta medicinal em uma escola valoriza o cultivo de plantas medicinais e integra conhecimentos populares e científicos. Este trabalho relata um projeto realizado com alunos da Escola da Associação de Pais e Amigos dos Surdos Foz do Iguaçu (APASFI). O objetivo foi promover a Educação Ambiental e o uso tradicional de plantas medicinais, através de uma palestra teórica e da implantação de uma horta medicinal escolar. A atividade incluiu a confecção de vasos e o plantio de espécies medicinais. Observou-se que poucos alunos conheciam o uso dessas plantas, mas muitos mostraram interesse durante a palestra e o plantio.
Camuflagem social e diagnóstico tardio de autismo em mulheres: uma revisão integrativa
Authors: Otoni Pereira Miranda Érica , Maria Pereira Fontes Chagas Lisandra Maria
Published: September 2024

Introdução. O transtorno do espectro autista (TEA) é um transtorno do neurodesenvolvimento caracterizado por comportamentos repetitivos e déficits na comunicação e na interação social. Apesar de o diagnóstico ocorrer, comumente, aos 4 a 5 anos de idade, por meio sobretudo de questionários, apenas 1/5 das mulheres têm seu diagnóstico anterior aos 11 anos, fato que, somado à menor proporção de mulheres com o transtorno suscita a busca pelo porquê dessa discrepância, cuja resposta pode permear o predomínio do fenômeno da camuflagem nesse grupo. Objetivo. essa revisão objetiva discutir a influência da camuflagem social da mulher sobre o diagnóstico tardio do quadro de transtorno do espectro autista. Método. Foi realizada uma revisão integrativa nas bases de dados BVS e PUBMED, resultando em 36 artigos selecionados após aplicação dos critérios de inclusão e de exclusão definidos. Resultados. A camuflagem se pauta no mascaramento de determinadas características, sendo mais praticada por portadores de TEA, implicando consequências severas aos praticantes, como exaustão e ansiedade. O fenômeno teve suas características básicas associadas ao fenótipo feminino do autismo já em 1992 para explicar o fenótipo e o subdiagnóstico nesse grupo. Trata-se de uma prática mais realizada por mulheres autistas, conforme estudos, devido, dentre outros fatores, às maiores demandas sociais impostas diante da estereotipagem de gênero inerente. Conclusão. Assim, além do fenótipo autista feminino ser diferente do masculino, a camuflagem ameniza esse, dificultando a identificação do transtorno tanto por especialistas, quanto pelas ferramentas de diagnóstico e por aqueles que convivem com o indivíduo.
Canine Disease Prediction using Multi-Directional Intensity Proportional Pattern with Correlated Textural Neural Network
Authors: Taranum Ayesha , Metan Jyoti , Yogegowda Prasad Adaguru , Krishnappa Chandrashekar Dimbachamanahalli
Published: September 2024

Data optimization is crucial for enhancing prediction accuracy and similarity identification in texture learning systems, especially for predicting canine diseases. Traditional data retrieval methods often struggle with accuracy and efficiency, particularly when dealing with large datasets. This study presents a novel approach combining Multi-Directional Intensity Proportional Pattern (MDIPP) with a Similarity Measure (SM) system to improve data relevance and similarity estimation. The model organizes data into a paged database structure, which speeds up search operations. A neural network, Correlated Textural Neural Network (CTNN), forecasts the relevance of feature attributes and sorts matching indexes to predict canine diseases based on Test data. The CTNN model incorporates a correlation factor among features to enhance prediction accuracy. The relevance of data is determined using an upgraded neural network that accounts for these correlations. The study evaluates performance based on precision, recall, F1-score, and data retrieval accuracy, comparing the results with state-of-the-art techniques. By improving the organization and indexing of data and refining the prediction process, this approach aims to advance data validation and the prediction of canine diseases in large-scale texture learning systems
3D VAE Video Prediction Model with Kullback Leibler Loss Enhancement
Authors: Al Mokhtar Zahraa , Dawwd Shefa
Published: September 2024

The Video Prediction (VP) models adopted many techniques to build suitable structures to extract the spatiotemporal features and predict the future frame. The VP techniques extracted the spatial and temporal features in separated models and then fused both features to generate the future frame. However, these architectures suffered from the design complexity and time for prediction required. So, many efforts introduced VP based on decreasing design complexity and producing good results. This study produces the VP model based on a Three-Dimensional Variational Auto Encoder (3D VAE). The proposed model builds all layers depending on 3D convolutional layers. This leads to better extraction of spatiotemporal information and decreases the design complexity. Second, the Kullback Leibler Loss (KL Loss) is enhanced by a 3D sampling stage which allows to calculation of the 3D latent loss. This helps to extract the better and proper spatiotemporal latent variable from the 3D Encoder. The 3D sampling represents a good regularizer in the model. The proposed model outperforms in terms of SNR=34.8673, SSIM= 0.9616 which applied to Karlsruhe Institute of Technology and Toyota Technological Institute (KITTI) and Caltech pedestrian datasets and records 5.2 M parameters.
Pandemi Sonrası Sağlık Prpfesyonellerinde Merhamet Yorgunluğu ve Yaşam Kalitesi Arasındaki İlişki: Kesitsel Bir Çalışma
Authors: Şahin Merve , Salik Hava , Demirkıran Fatma
Published: September 2024

Bu çalışmanın amacı, pandemi sonrası sağlık profesyonellerinde merhamet yorgunluğu ve çalışma yaşam kalitesi arasındaki ilişkiyi belirlemektir. Kesitsel tipteki bu çalışma 2022 yılı Mayıs-Ağustos ayları arasında Türkiye’nin batısında yer alan bir devlet hastanesinde gerçekleştirilmiştir. Çalışmanın evrenini 280, örneklemini ise 158 sağlık çalışanı oluşturmaktadır. Araştırma verileri kişisel bilgi formu, merhamet yorgunluğu ölçeği ve çalışanlar için yaşam kalitesi ölçeği ile toplanmıştır. Verilerin analizinde student-t test, one way anova testi ve pearson korelasyon kullanılmıştır. Çalışmaya 158 sağlık profesyoneli katılmış olup bunların %64.6’sı hemşire, %10.8’i doktor, %8.9’u paramedik/ATT, %6.3’ü sağlık memuru, %6.3’ü ebe, %1.9'u psikolog ve %1.3'ü diyetisyen oluşturmuştur. Sağlık profesyonellerinin yaş, Covid-19 hastalığı geçirme durumu, meslek ve birimde çalışma yılı değişkenlerine göre merhamet yorgunluğu arasında istatistiksel olarak anlamlı farklılık bulunmuştur (p<0.05). Sağlık profesyonellerinin yaş, cinsiyet, çocuk sahibi olma, eğitim durumu, meslek, birimde çalışma yılı ve Covid-19 hastalarına sağlık hizmeti veren bölümde çalışma durum değişkenlerine göre çalışma yaşam kalitesi arasında istatistiksel olarak anlamlı farklılık bulunmuştur (p<0.05). Merhamet yorgunluğu ölçeğinin tüm alt boyutları ile çalışma yaşam kalitesi ölçeğinin alt boyutu olan mesleki tatmin ile istatistiksel olarak anlamlı ilişki saptanmıştır (p<0.05). Araştırma bulguları doğrultusunda sağlık profesyonellerinin merhamet yorgunluğunu azaltmak ve çalışma yaşam kalitesini arttırmak için çalışma ortamlarının düzenlenmesi, ruhsal sağlıklarını koruyan destek ve uygulamaların sağlanması önerilmektedir.
Osteonecrose maxilo-mandibular associada ao uso de bifosfonatos: tratamento com oxigenoterapia hiperbárica: revisão de literatura
Authors: Silva Daniela Fardim da , Silva Pedro Henrique Pereira da , Santos Thaysa Maschiatti , Silva Vanessa Gonçalves , Langa Weslley Alexsander de Oliveira , Guimarães Frederico Barbosa , Bourguignon Filho Aguimar de Matos
Published: September 2024

de Bifosfonatos através da demonstração da farmacocinética dos Bifosfonatos no organismo, análise da ação da Câmara Hiperbárica no tratamento da Osteonecrose a nível celular, esclarecendo a relação dos tecidos maxilares e mandibulares com anecrose e sua correlação com a terapia hiperbárica. Para tanto, procede-se à revisão bibliográfica de literatura de 25 artigos entre os anos de 2010 até 2024, sendo selecionados 21 dentro dos critérios de inclusão. Desse modo, observa-se que o tratamento da Osteonecrose maxilo-mandibular por uso de Bifosfonatos através do uso da câmara hiperbárica, quando bem indicada, demostra resultados satisfatórios na maioria dos casos, o que permite concluir que a mesma possui propriedades positivas e quanto a indicação desta forma de tratamento.
Impacto do hipertireoidismo nas doenças cardíacas: uma revisão sistemática
Authors: Lopes Cristianne Confessor Castilho , Azzini Vitor Ohana Marques , Lopes Eduardo Barbosa , Pitanga Fábio Herget , Sales Juelkson Vieira , Ferreira Junior Joacir , Borges Lucas Sena dos Santos , Eickoff Tulio Dylan , Guimarães Larissa Silva , Furlan Daniel , Lima Patrícia Cota , Defáveri Lívia Strital , Sevá Ana Clara , Souto Raul , Souza Maria Eduarda Carvalho de , Trofino Gabriela Costa , Fournier Rafael Coutinho , Santos Eduardo Afonso Zechlinski dos , Trombetta Thalys Augusto Menegazzo , Vanuzzi Fabio Kopp , Dias Túlio Gamio
Published: September 2024

Introdução: As consequências cardiovasculares do hipertireoidismo são particularmente preocupantes, pois é capaz de causar e agravar uma variedade de doenças cardíacas, desde arritmias até insuficiência cardíaca, que são preocupações clínicas importantes, porque podem causar elevada morbimortalidade. Objetivo: Fornecer uma visão abrangente e atualizada sobre dos efeitos do hipertireoidismo no sistema cardiovascular. Métodos: Este estudo constitui-se em revisão sistemática, classificada como exploratória e descritiva. A elaboração da pesquisa foi pesquisa bibliográfica em bases de dados eletrônicas sobre métodos associados à RSL (Revisão Sistemática da Literatura) e às aplicações do SMARTER (Simple Multi-Attribute Rating Technique using Exploiting Rankings). Resultados: Uma busca sistemática abrangente da literatura rendeu um total de 4490 artigos referentes ao impacto do hipertireoidismo nas doenças cardíacas, destes, 26 artigos se tornaram elegíveis para compor esta revisão sistemática. Conclusão: O hipertireoidismo exerce um impacto significativo sobre o sistema cardiovascular, contribuindo para o desenvolvimento e a exacerbação de várias doenças cardíacas.
Câncer de mama maligno em mulheres durante 2019 e 2020
Authors: Gonçalves Késsia Margarida Barreto , Pires Ananda Regis de Oliveira , Mota Érica Amorim , Santos Juliana Regina Freitas dos , Andrade Filha Simone Valente Campos , Nogueira Janaína Ribeiro Lordelo
Published: September 2024

O câncer da mama é o tipo de câncer que mais acomete as mulheres no Brasil, excluindo o câncer de pele não melanoma. Nos anos de 2010 e 2018, foram evidenciadas, respectivamente, 12.600 e 17.436 mortes por câncer de mama entre mulheres, sendo maior percentual observado na faixa de idade < 70 anos, seguida da faixa de 50 a 59 anos, entre mulheres brancas, com escolaridade menor que 8 anos. É importante registrar, por ﬁm, o aumento contínuo, desde 2012, da oferta de mamograﬁas de rastreamento para as mulheres na faixa etária recomendada (de 50 a 69 anos).
Dentes natais e neonatais em recém-nascidos de hospital geral no estado da Bahia: relato de casos incomuns
Authors: Garcia Juliana Jorge , Zhang Mengting , Gomes Leandro Silvestre de Oliveira , Gomes Nilvia Maria Lima , Moreira Lucya Giselle Costa , Mattos Fabiane Pereira Santos de , Pereira João Victor da Silva , Perez Adriano Silva
Published: September 2024

Dentes natais e neonatais são dentes com irrompimento prematuro na cavidade oral. São pouco comuns e no momento do nascimento ou nos primeiros dias de vida já é possível observa-los. Normalmente são dentes com defeitos de formação, mobilidade que geram desconfortos e dificuldade durante a amamentação. Este estudo objetiva relatar dois casos sobre esses dentes em região anterior de mandíbula, onde foi necessário realizar exodontia, devido ao alto risco de descolamento precoce das unidades. Diante da presença dessas unidades dentárias o tratamento indicado pode ser a sua remoção, para prevenir dificuldades na amamentação e anular as possibilidades de broncoaspiração.
إدارة رأس المال البشري والإبداع التنظيمي: دراسة ميدانية لبعض الجهات الحكومية في دولة الكويت
Authors: المطيري يوسف محمد , القريوتي محمد قاسم
Published: September 2024

تهدف هذه الدراسة إلى الوقوف على الاهتمام الذي توليه الجهات الحكومية في دولة الكويت لإدارة رأس المال البشري بوصفه أحد المقومات الأساسية لرأس المال الفكري (Intellectual Capital) في قدرته على تعزيز الإبداع، والتحقق من وجود علاقات ارتباط معنوية، بين رأس المال البشري والإبداع التنظيمي. شملت الدراسة عينة عشوائية طبقية من الموظفين الإداريين على مستوى المركز في الوزارات والهيئات والمؤسسات العامة، وتم استخدام الأساليب الإحصائية المناسبة لتحليل البيانات واختبار الفرضيات للوصول للنتائج والتوصيات المناسبة، التي من شأن الأخذ بها دعم الاهتمام برأس المال البشري بما ينعكس على مستوى الإبداع ورفع مستوى أداء الجهات الحكومية. وقد توصلت الدراسة إلى أن العاملين في هذه الجهات يقيّمون اهتمام الجهات الحكومية بإدارة رأس المال البشري والإبداع بدرجة متوسط. فقد بلغ تقييم الاهتمام بإدارة رأس المال البشري (3.12)، والإبداع (3.23) على سلم ليكرت الخماسي، وإلى وجود ارتباطات إيجابية قوية (*824.) وتأثيرات ذات دلالة معنوية لإدارة رأس المال البشري تفسر %67 من عملية الإبداع التنظيمي، وبناءً على ذلك يوصي الباحثان بضرورة الاهتمام بإدارة رأس المال البشري وإعطاء جهود التنمية البشرية بعداً إستراتيجيًّا.
تصنيف مجموعة شركات مايلز آند سنو: مقارنة بين عينات الخدمات والتصنيع
Authors: هاينز ريتشارد , قطينه مجدي , بلشكو لاري
Published: September 2024

تمثل هذه الدراسة تحقيقًا بملفات استراتيجيات Miles and Snow (1978) في عينات مأخوذة من قطاعين صناعيين مختلفين: شركات الخدمات المالية وشركات تصنيع المنتجات. وبشكل خاص، يستقصي المؤلفون كيفية اختلاف مجموعات استراتيجيات مايلز وسنو في الهيكل التنظيمي، والتوجه التسويقي، والأداء. شير النتائج إلى أن الشركات المصنفة كـ"مستكشفين" و"محللين" تتمتع بتوجه أكبر نحو السوق بشكل عام، فضلاً عن كونها أكثر تركيزاً على المنافسين مقارنةً بنظيراتها من فئتي "الدفاعيين" و"المتفاعلين". بالإضافة إلى ذلك، أظهرت الشركات المالية المتفاعلة أدنى مستويات من الحصة السوقية وأداء الأرباح. كما توضح النتائج أن المحللين في عينة تصنيع المنتجات حققوا أعلى مستوى من حيث كل من الحصة السوقية والأرباح. باستثناء محللي تصنيع المنتجات، كان أداء الأرباح لمستكشفي الخدمات أيضًا متفوقًا على الأنواع الأخرى من M&S.
Modeling the Impact of Ergonomic Interventions and Occupational Factors on Work-Related Musculoskeletal Disorders in the Neck of Office Workers with Machine Learning Methods
Authors: Sohrabi Mohammad Sadegh , Khotanlou Hassan , Heidarimoghadam Rashid , Mohammadfam Iraj , Babamiri Mohammad , Soltanian Ali Reza
Published: September 2024

Background: Modeling with methods based on machine learning (ML) and artificial intelligence can help understand the complex relationships between ergonomic risk factors and employee health. The aim of this study was to use ML methods to estimate the effect of individual factors, ergonomic interventions, quality of work life (QWL), and productivity on work-related musculoskeletal disorders (WMSDs) in the neck area of office workers. Study Design: A quasi-randomized control trial. Methods: To measure the impact of interventions, modeling with the ML method was performed on the data of a quasi-randomized control trial. The data included the information of 311 office workers (aged 32.04±5.34). Method neighborhood component analysis (NCA) was used to measure the effect of factors affecting WMSDs, and then support vector machines (SVMs) and decision tree algorithms were utilized to classify the decrease or increase of disorders. Results: Three classified models were designed according to the follow-up times of the field study, with accuracies of 86.5%, 80.3%, and 69%, respectively. These models could estimate most influencer factors with acceptable sensitivity. The main factors included age, body mass index, interventions, QWL, some subscales, and several psychological factors. Models predicted that relative absenteeism and presenteeism were not related to the outputs. Conclusion: In this study, the focus was on disorders in the neck, and the obtained models revealed that individual and management interventions can be the main factors in reducing WMSDs in the neck. Modeling with ML methods can create a new understanding of the relationships between variables affecting WMSDs.
Духовные направления в русской словесности XX века. Кн. 1: Иван Бунин, Максим Горький, Вячеслав Иванов, Сергей Есенин, Андрей Платонов
Authors: Моторин А. В.
Published: September 2024

В книге рассматриваются духовные направления русской художественной словесности XX века. Образное выражение народного самосознания в творчестве лучших писателей наиболее полно отражает своеобразие и многообразие этого самосознания, предопределяя его будущее развитие. Художественное словесное осуществление духовных устремлений народа обладает особой внушающей силой, прямо и разнообразно воздействует на жизнь общества, государства. Издание предназначено для студентов, аспирантов, преподавателей вузов, учителей, старшеклассников и всех, кто увлекается историей русского слова и русского духа.
Origen del Tribunal Supremo de Elecciones: contexto y fuentes inspiracionales
Authors: Chinchilla Carolina Mora , Gonzalez Luis Antonio Sobrado
Published: September 2024

El presente artículo tiene como objetivo resaltar algunos elementos de otras constituciones de la región latinoamericana que inspiraron la creación, en 1949, del Tribunal Supremo de Elecciones (TSE) y sus características. A la vez, se busca destacar los elementos donde presenta una verdadera originalidad. Así, se rescata el aporte esencial para poder contar con un padrón electoral confiable que brindó la configuración del Registro Civil como dependencia del TSE desde la creación de este. El desempeño exitoso del TSE a lo largo de estos 75 años ha demostrado que estos elementos básicos fueron esenciales para su fortalecimiento, aunque otros aspectos innovadores han permitido un mejor posicionamiento de la institución.