bluuebunny/crossref_metadata_2025 huggingface dataset:
Recurrent episodes of severe bleeding caused by congenital factor XIII deficiency in a dog
Authors: Kong Lyndsay R. , Snead Elisabeth C. R. , Burgess Hilary , Dhumeaux Marc P.
Published: October 2014

Case Description—A 5-year-old castrated male Toy Poodle cross was evaluated because of lethargy, inappetence, and suspected abdominal hemorrhage. The dog had been evaluated on 4 other occasions for episodes of excessive bleeding associated with trauma or surgical procedures.

Clinical Findings—At previous evaluations, results of repeated measurements of prothrombin time, partial thromboplastin time, and buccal mucosal bleeding time were unremarkable; activated clotting time, plasma von Willebrand factor concentration, results of platelet function testing, and plasma factor VII, VIII, IX, X, XI, and XII concentrations were considered normal. At this evaluation, clinicopathologic analyses revealed mild regenerative anemia that progressed over a 4-day period to moderate regenerative anemia and acute inflammation with panhypoproteinemia. Abdominal ultrasonography revealed a large mass (suspected to be a hematoma) near the urinary bladder. Rotational thromboelastometry revealed that clotting times were within reference limits, with abnormal clot formation times and clot firmness. The result of a factor XIII (FXIII) clot solubility assay confirmed FXIII deficiency.

Treatment and Outcome—The dog's bleeding diathesis resolved with inpatient care and IV fluid therapy, although plasma transfusions had been required at previous evaluations. Seven months after discharge from the hospital, the dog continued to do well clinically, although it had several additional episodes of excessive bleeding.

Clinical Relevance—To the authors’ knowledge, this is the first reported case of congenital FXIII deficiency in a dog. In addition to more common inherited coagulopathies, FXIII deficiency should be a differential diagnosis for dogs with episodes of excessive bleeding and apparently normal results of standard coagulation tests.
Scanning Probe Microscope-Based Fluid Dispensing
Authors: Ghatkesar Murali , Garza Hector , Heuck Friedjof , Staufer Urs
Published: October 2014

Advances in micro and nano fabrication technologies have enabled fabrication of smaller and more sensitive devices for applications not only in solid-state physics but also in medicine and biology. The demand for devices that can precisely transport material, specifically fluids are continuously increasing. Therefore, integration of various technologies with numerous functionalities in one single device is important. Scanning probe microscope (SPM) is one such device that has evolved from atomic force microscope for imaging to a variety of microscopes by integrating different physical and chemical mechanisms. In this article, we review a particular class of SPM devices that are suited for fluid dispensing. We review their fabrication methods, fluid-pumping mechanisms, real-time monitoring of dispensing, physics of dispensing, and droplet characterization. Some of the examples where these probes have already been applied are also described. Finally, we conclude with an outlook and future scope for these devices where femtolitre or smaller volumes of liquid handling are needed.
A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
Authors: Xia Qing , Zhang Huazheng , Sun Xuefei , Zhao Haijuan , Wu Lingfang , Zhu Dan , Yang Guanghui , Shao Yanyan , Zhang Xiaoxue , Mao Xin , Zhang Lanzhen , She Gaimei
Published: October 2014

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and 13C-NMR spectral data.
A Procedure to Map Subsidence at the Regional Scale Using the Persistent Scatterer Interferometry (PSI) Technique
Authors: Rosi Ascanio , Agostini Andrea , Tofani Veronica , Casagli Nicola
Published: October 2014

In this paper, we present a procedure to map subsidence at the regional scale by means of persistent scatterer interferometry (PSI). Subsidence analysis is usually restricted to plain areas and where the presence of this phenomenon is already known. The proposed procedure allows a fast identification of subsidences in large and hilly-mountainous areas. The test area is the Tuscany region, in Central Italy, where several areas are affected by natural and anthropogenic subsidence and where PSI data acquired by the Envisat satellite are available both in ascending and descending orbit. The procedure consists of the definition of the vertical and horizontal components of the deformation measured by satellite at first, then of the calculation of the “real” displacement direction, so that mainly vertical deformations can be individuated and mapped.
The Beneficial Effect of Electro-acupuncture Given at PC6 (Neiguan-point) by the Increase in Cardiac Transient Outward K+ Current Channel Which Depends on the Gene and Protein Expressions in Artificially Induced Myocardial Ischemia Rats
Authors: Wang Ying , Wang Wei , Li Di , Li Jiquan , Dai Jianyu , Liu Yufu , Li Chunri , Zhang Xiaolu , Rong Peijing , Chen Yiguo
Published: October 2014

This study explored the mechanism of electro-acupuncture (EA) at PC6 to improve the heart function by regulating the cardiac transient outward potassium current (=Ito) channel in myocardial ischemia (MI). Kv1.4 is the main component of the slow Ito (Ito. s) channel. Kv4.2 and Kv4.3
are the main components of the fast Ito (Ito. f) channel. KChIP2 is a compound protein of Ito channel. In this experiment, MI was induced by injecting isoproterenol in rats, and the gene and protein expressions of Kv1.4, Kv4.2, Kv4.3 and KChIP2 were lower [The gene and protein decreased (42.8±4.3)%
and (37.2±4.7)% respectively.] than the control rats significantly (p < 0.05). After MI induction, the MI rats were divided into three groups, including PC6, LU7 (Lieque-point) and Non-acupoint group which were acupunctured at once a day for 7 days respectively. After EA at PC6 and
LU7, the gene and protein expressions showed obvious increased [EA at PC6: the gene and protein increased (50.2±5.4)% and (39.1±5.3)% respectively. EA at LU7: the gene and protein increased (24.6±2.8)% and (22.0±5.5)% respectively] and they are all higher than MI
rats significantly (p < 0.05). EA at PC6 and LU7 showed the same variation, and the effects of EA at PC6 and LU7 were better than Non-acupuncture-point (p < 0.05). The effects of EA at PC6 were significantly better [The gene and protein increased (19.7±2.7)% and (14.1±4.4)%
respectively] than LU7 (p < 0.05). PC6 is an acupoint of the pericardium meridian, and the pericardium meridian which corresponds to adrenal gland according to Omura Y's research, can affect the heart function directly. LU7 belong to the lung meridian, and the lung plays an important factor
in blood circulation according to TCM. So PC6 is more effective than LU7 on heart function regulation. The results suggested that PC6 showed the target effect of meridian specificity on regulating the Kv channel in MI.
The Impact of Acupuncture Treatment on Nitric Oxide (NO) in Migraine Patients
Authors: Gündüztepe Yasemin , Mit Setenay , Geçioglu Ersel , Gurbuz Neslihan , Salkacı Osman , Severcan Cinar , Çevik Cemal
Published: October 2014

The purpose of this study is to contribute to efforts to understand the pathophysiology of migraine and create an alternative perspective for prophylaxis and treatment of migraine attacks. Acupuncture treatment was applied to the 22 volunteer migraine patients. The acupuncture treatment
consists of 5 sessions with 2 sessions per week. Blood samples have been collected before performing acupuncture, after the 1st session and after the 5th session of the acupuncture. And for the control group blood samples were collected only once. In our study the mean serum NO levels in healthy
people were (3,58±0,53) while patients with migraine group were (5,55±0,70) respectively. Serum NO levels were 55% higher in migraine group compared to the control group The NO concentration also decreased after 5th session (30%) (p<0.05). After the 1st sessions NO level decreased
4,86% in the migraine group. After the 5th session NO level decreased 30,63% in the migraine group. After the 5th session NO level decreased 27,08% compared to 1st session in the migraine group. After the 1st session of acupuncture treatment, level of NO in migraine group were 4,86% and it
is reduced but statistically not significant. After the 5th acupuncture treatment serum NO levels were reduced to (3,85±0.62) 30,63% in migraine group and were statistically lower (p<0.05). After the 5th session NO level decreased 27,08% compared to 1st session in the migraine group.
In this study, acupuncture treatment is appeared to be effective by lowering the levels of serum NO and acupuncture has cumulative effects. Although there are earlier studies showing the effect of NO in migraine, this has been the 1st study in this field, which shows the effect of acupuncture
on NO in migraine patients.
A database of life-history traits of European amphibians
Authors: Trochet Audrey , Moulherat Sylvain , Calvez Olivier , Stevens Virginie , Clobert Jean , Schmeller Dirk
Published: October 2014

In the current context of climate change and landscape fragmentation, efficient conservation strategies require the explicit consideration of life history traits. This is particularly true for amphibians, which are highly threatened worldwide, composed by more than 7400 species, which is constitute one of the most species-rich vertebrate groups. The collection of information on life history traits is difficult due to the ecology of species and remoteness of their habitats. It is therefore not surprising that our knowledge is limited, and missing information on certain life history traits are common for in this species group. We compiled data on amphibian life history traits from literature in an extensive database with morphological and behavioral traits, habitat preferences and movement abilities for 86 European amphibian species (50 Anuran and 36 Urodela species). When it were available, we reported data for males, females, juveniles and tadpoles. Our database may serve as an important starting point for further analyses regarding amphibian conservation.
Literature and Practice: A Critical Review of MOOCs
Authors: Chiappe-Laverde Andrés , Hine Nicolás , Martínez-Silva José Andrés
Published: October 2014

This article focuses on a review of both literature and practical experiences concerning MOOCs. The literature analyzed was published in peer-reviewed journals between 2007 and 2013. 268 items were selected for this study, of which 100 were analyzed in detail. The issues raised by this analysis were used as the criteria for the analysis of 10 current empirical MOOC experiences. The literature study highlighted the rapid growth in interest in understanding MOOCs and seeking to understand the pedagogic frameworks most relevant to their adoption and the importance of the concept of openness embodied within them. More recently a new emphasis has been emerging where institutional factors, particularly those concerned with financial viability, certification and retention have been highlighted. The analysis of current practice showed that many of the concerns in the academic literature were absent from not only the practices embodied in current MOOC-based learning experiences but seem to have been ignored in the conceptual phase of implementing a MOOC-based teaching model. In practice therefore, most of the current MOOC offer is only a pale reflection of the conceptualization that gave them rise and has been shown to be significant in the literature. In particular the true essence encapsulated in the concept described as Openness has been largely lost in practice.

Este artículo se enfoca en una revisión tanto de literatura como de experiencias prácticas acerca de los MOOC. Los textos analizados fueron publicados en revistas entre los años 2007 y 2013. Se seleccionaron 268 artículos para este estudio, de los cuales 100 se analizaron en detalle. Los asuntos encontrados en la revisión se utilizaron posteriormente como criterios de análisis de 10 experiencias empíricas sobre MOOC. La literatura estudiada resalta el rápido crecimiento en el interés por comprender los MOOC, sus fundamentos pedagógicos así como la importancia del concepto de lo abierto que se encuentra en ellos. Un nuevo énfasis ha surgido recientemente en la literatura donde los factores institucionales, particularmente aquellos concernientes con la viabilidad financiera, la certificación y la deserción se encuentran resaltados. El análisis de la prácticas actuales muestra que muchos de los temas relevantes expresados en la literatura académica están ausentes no solo de las prácticas relacionadas con las experiencias de aprendizaje basadas en los MOOC sino que se han ignorado como sustento de la implementación de un modelo de enseñanza basada en ellos. Del análisis realizado se concluye que buena parte de la actual oferta de MOOC es tan solo un pálido reflejo de la conceptualización que les dio origen y que se muestra significativa en la literatura. En síntesis, la verdadera esencia del concepto de lo abierto se ha perdido en la práctica.
Analysis and Implications of the Impact of MOOC Movement in the Scientific Community: JCR and Scopus (2010-13)
Authors: López-Meneses Eloy , Vázquez-Cano Esteban , Román-Graván Pedro
Published: October 2014

The emergence of massive open online course (MOOCs) has been a turning point for the academic world and, especially, in the design and provision of training courses in Higher Education. Now that the first moments of the information explosion have passed, a rigorous analysis of the effect of the movement in high-impact scientific world is needed in order to assess the state of the art and future lines of research. This study analyzes the impact of the MOOC movement in the form of scientific article during the birth and explosion period (2010-2013) in two of the most relevant databases: Journal Citation Reports (WoS) and Scopus (Scimago). We present, through a descriptive and quantitative methodology, the most significant bibliometric data according to citation index and database impact. Furthermore, with the use of a methodology based on social network analysis (SNA), an analysis of the article’s keyword co-occurrence is presented through graphs to determine the fields of study and research. The results show that both the number of articles published and the citations received in both databases present a medium-low significant impact, and the conceptual network of relationships in the abstracts and keywords does not reflect the current analysis developed in general educational media.

La irrupción de los MOOC (Massive Online Open Courses) ha supuesto un punto de inflexión en el mundo académico y, especialmente, en el diseño y oferta de cursos formativos en la Educación Superior. Una vez superado el primer momento de explosión informativa, se precisan análisis rigurosos sobre la repercusión del movimiento en el mundo científico con más alto impacto para valorar el estado de la cuestión y las líneas de investigación futuras. El presente estudio analiza el impacto del movimiento MOOC en forma de artículo científico durante el período de nacimiento y explosión (2010-2013) en dos de las bases de datos de revistas científicas más relevantes, Journal Citation Reports (WoS) y Scopus (Scimago). A través de una metodología descriptiva y cuantitativa se presentan los datos bibliométricos más significativos por su índice de cita y repercusión. Asimismo, mediante la metodología de Análisis de Redes Sociales (ARS) se realiza un análisis de co-ocurrencia con representación en grafo de las palabras clave de los artículos para la determinación de los campos de estudio e investigación. Los resultados muestran que tanto el número de artículos publicados en ambas bases de datos como las citas que reciben presentan un índice medio-bajo de impacto y la red temática de interrelaciones en los resúmenes y palabras clave de los artículos publicados no reflejan la crítica actual de los medios divulgativos generales.
Young Learners’ Objectives Related to Multimedia Use and Homework Completion
Authors: Öngün Erdem , Demirag Askin
Published: October 2014

Individuals of all ages are inevitably affected by today’s technology. The main purpose of this study is to explore the objectives of 8th grade students related to the utilization of multimedia instruments ranging from personal computers to the Internet use while they are doing their homework. Specifically, it tries to find out whether there is a significant relationship between «for what purposes 8th graders use multimedia tools» and «which personal traits are reinforced while doing homework with multimedia tools?», where gender differences were also taken into consideration in the analysis of the related items in the questionnaire form. The population of the study is made up of 435 students who were randomly selected from five secondary schools in the city of Istanbul, Turkey. As a data collection method, a questionnaire form with a set of related research questions was used. Findings from the study show that 8th graders in their use of multimedia platforms are provided with a more interactive and independent learning environment where they can find more learning aids while accomplishing their homework objectives. Gender-based evidence from the study shows that digitally, male students are more active and they exploit the fun side of homework more compared to their female counterparts.

Las personas de todas las edades se ven inevitablemente afectadas por la tecnología de hoy. El principal propósito de este estudio es analizar en los estudiantes de octavo grado la relación entre los cambios experimentados en la utilización de los instrumentos multimedia y el uso de los ordenadores personales e Internet mientras están haciendo sus deberes. En concreto, se trata de averiguar si existe una relación significativa entre «para qué fines los estudiantes de octavo grado usan herramientas multimedia» y «qué rasgos personales se refuerzan mientras hacen los deberes con herramientas multimedia», y esto, teniendo también en cuenta las diferencias de género en el análisis de las partidas recogidas en el formulario de preguntas. La población del estudio se compone de 435 estudiantes elegidos aleatoriamente de cinco escuelas secundarias en la ciudad de Estambul, en Turquía. El método utilizado para la recolección de datos consistió en un cuestionario con preguntas relacionadas con la investigación. Los hallazgos del estudio evidencian que los estudiantes de octavo nivel que utilizan las plataformas multimedia reflejan un ambiente de aprendizaje más independiente e interactivo en el que encuentran un respaldo mayor mientras realizan sus tareas. Atendiendo a la perspectiva de género, el estudio muestra que, digitalmente, los estudiantes masculinos son más activos y desarrollan más el lado divertido de las tareas que sus compañeras.
Cyberbullying trough Mobile Phone and the Internet in Dating Relationships among Youth People
Authors: Durán-Segura Mercedes , Martínez-Pecino Roberto
Published: October 2014

Cyberbullying is a phenomenon that has been extensively analysed amongst adolescents. However, in Spain, there have been few studies of young adults and particularly of their romantic relationships in the digital context. This study analyses cyberbullying in romantic relationships in mobile and digital exchanges between partners, in a sample comprising 336 students using quantitative methodology. The results show that 57,2% of the sample admit to having been victimised by their partner by mobile phone and 27,4% via the Internet. The percentage of victimised males was higher than that of females. 47,6% affirmed that they had bullied their partner by mobile phone and 14% over the Internet. The percentage of males who did so was higher than that of females. The regression analyses showed correlation between having been victimised by a partner via one of these media and having experienced cyberbulling in other by means of the same technological medium. The effects of this interaction highlight that males victimised through the use of mobile phones or the Internet are involved, to a greater extent than victimised females, as the perpetrators in this phenomenon. The results suggest modernisation in the types of violence that young adults experience in their relationships.

El ciberacoso es un fenómeno ampliamente analizado entre adolescentes, sin embargo en España ha sido poco estudiado entre jóvenes y particularmente en sus relaciones de noviazgo. Empleando una metodología cuantitativa este estudio analiza el ciberacoso mediante el teléfono móvil e Internet en las relaciones de noviazgo en una muestra compuesta por 336 estudiantes universitarios. El análisis de resultados indica que un 57,2% declara haber sido victimizado por su pareja mediante el teléfono móvil, y un 27,4% a través de Internet. El porcentaje de chicos victimizados fue mayor que el de las chicas. Un 47,6% declara haber acosado a su pareja a través del teléfono móvil, y un 14% a través de Internet. El porcentaje de chicos que lo ejerció fue superior al de las chicas. Los análisis de regresión muestran la relación entre haber sido victimizado por la pareja a través de uno de estos medios y el ejercicio del ciberacoso hacia la pareja mediante el mismo medio tecnológico. Los efectos de interacción ponen de manifiesto que los chicos victimizados a través del teléfono móvil o de Internet se implican, en mayor medida que las chicas victimizadas, como agresores en este fenómeno. Los resultados sugieren una modernización en los tipos de violencia que experimenta la juventud en sus relaciones de pareja.
La normalisation : dynamique opaque ou bonne gouvernance mondiale ?
Authors: Borde Jean-Michel , Vaucelle Alain , Hudrisier Henri
Published: October 2014

Les enjeux planétaires, pour spectaculaires et omniprésents qu’ils soient, sont observés et décrits au moyen d’outils aussi spécifiques que banalisés, ce sont les normes techniques internationales. Nous réfléchissons ici à leur rôle vis-à-vis des communautés qu’elles encadrent, voire conditionnent. Une plongée dans la complexité de l’organisation du management normatif permet, au prix de quelques efforts, de percevoir les leviers et leurs effets. Est-il possible de s’approprier ceux-ci ? Au moins collectivement et pour quoi faire ? Nous conclurons sur quelques règles disciplinaires potentiellement à explorer, sinon à suivre.
Nouvelle gestion publique et recomposition professionnelle dans le secteur social
Authors: Molina Yvette
Published: October 2014

La nouvelle gestion publique introduite dans les services publics et associatifs du secteur social dans les années 1980-1990 prend sa source dans le courant managérial néolibéral. Elle se traduit par deux composantes majeures : la mise en œuvre de nouveaux outils d’évaluation et de contrôle de l’activité des organisations et des pratiques professionnelles d’une part, des réorganisations institutionnelles d’autre part. Cet article analyse l’impact de cette logique gestionnaire au regard du vécu des professions du travail social tel que les acteurs en rendent compte à travers une enquête sociologique.
Analyser le travail social. Une approche intégrant l'agentivité et les rapports sociaux
Authors: Bachmann Laurence , Rodari Sophie
Published: October 2014

Cet article souligne la qualité heuristique d’une double grille d’interprétation pour analyser l’activation et, plus généralement, les interventions du travail social dans les nouveaux dispositifs d’aide. Il vise à rendre explicite cette double grille de lecture intégrant autant l’agentivité des individus que les rapports sociaux qui les traversent, double grille qui se devine parfois implicitement dans les recherches. Pour ce faire, nous nous appuyons sur une étude en cours sur l’attribution d’aide financière des assistantes sociales et assistants sociaux aux personnes surendettées en Suisse romande, dans un contexte où les professionnel-le-s bénéficient d’une relative marge de manœuvre en termes d’attribution.
L'innovation en PME et son accompagnement par les TIC : quels effets sur la performance ?
Authors: Deltour François , Lethiais Virginie
Published: October 2014

La capacité à innover des entreprises ainsi que leurs ressources TIC sont généralement reconnues comme des gages de leur compétitivité. Dans notre article, ces deux sources de performance sont étudiées dans le contexte des Petites et Moyennes Entreprises (PME), en analysant notamment les retombées de l’accompagnement de l’innovation par les TIC. Notre recherche s’appuie sur une double investigation : une enquête menée auprès de PME de la région Bretagne et une collecte en ligne des performances financières de ces mêmes entreprises. Sur un échantillon final de 1086 entreprises, nous évaluons économétriquement dans quelle mesure la performance des PME peut être expliquée par l’innovativité, les ressources TIC (humaines et matérielles), ainsi que par l’effet combiné de l’innovativité accompagnée par les technologies de l’information. Le recours à une variable d’interaction mesurant les TIC directement mobilisées pour soutenir l’innovation des PME constitue l’apport méthodologique de notre recherche. L’investigation montre que les technologies de l’information contribuent à augmenter la performance des PME lorsqu’elles accompagnent des innovations : l’innovativité des PME a des retombées positives sur leur performance dans la mesure où elle est accompagnée par des investissements en TIC ou bien par un usage plus poussé des technologies déjà présentes dans l’entreprise. A contrario , l’innovativité et les ressources TIC considérées isolément minorent le niveau de performance des firmes étudiées. Ces différents résultats sont discutés au regard des caractéristiques spécifiques des PME.
In-service and Pre-service Middle School Mathematics Teachers' Attitudes and Decisions Regarding Teaching Mathematics Using Mobile Phones
Authors: Daher Wajeeh M. , Baya'a Nimer
Published: October 2014

Several researches examined students' mathematics learning using mobile phones, while very few researches examined mathematics teaching using this new educational tool. This research attempts to analyze in-service and pre-service teachers' attitudes and decisions regarding mathematics teaching with mobile phones using activity theory. More specifically, three case studies are analyzed in this research: One concerns an in-service teacher who used mobile phones in her class, the second case study involves a pre-service teacher who collaborated with the in-service teacher to teach mathematics lessons using mobile phones, and the third case study is about 15 pre-service teachers who were observers of the experiment but did not use mobile phones in their teaching. We held one-hour semi-structured interviews with the in-service teacher, with the leading pre-service teacher and with the group of other observer pre-service teachers. This happened three times during the academic year: at the beginning of the experiment, after three months and after it ended.

The research findings indicate that different factors have an impact on the attitudes and decisions of the teacher: history of the teacher using technologies in teaching, perceptions of the teacher using technologies in teaching, community’s teacher, rules regulating the use of technologies in teaching mathematics, and division of labor. For example, questions as to who decides which technologies to use in the classroom and who should prepare the learning material for the students. Contradictions were identified in mathematics teachers' activity when utilizing mobile phones in their teaching. These contradictions hinder or slow such utilization. Community, especially its leading members, mediated and helped overcome the activity contradictions that arose throughout the experiment regarding the teaching processes in and/or out of the mathematics classroom.
Mobile Technology Applications for Manufacturing, Reduction of Muda (Waste) and the Effect on Manufacturing Economy and Efficiency
Authors: Huenerfauth Angela M
Published: October 2014

Mobile devices in the manufacturing setting offer mobility and information whenever and wherever it is needed; these advantages allow for a more efficient workflow and allow the user to make more informed decisions. Due to these advantages, companies are reducing muda (waste) by using mobile devices (implementing Lean Manufacturing) and therefore saving money. Some of the mobile applications discussed in this paper are the following: Augmented Reality for assembly training, pruefcubing, remotely-monitored shop floors, statistical process control (SPC), and change requests for construction, and the two types of muda (waste) reduced by these mobile applications are “unnecessary / excess motion and defects.”
Impacts of Different Mobile User Interfaces on Students’ Satisfaction for Learning Dijkstra’s Shortest Path Algorithm
Authors: Seraj Mazyar , Wong Chui Yin
Published: October 2014

This paper describes an experimental study of learning Dijkstra’s shortest path algorithm on mobile devices. The aim of the study is to investigate and compare the impacts of two different mobile screen user interfaces on students’ satisfaction for learning the technical subject. A mobile learning prototype was developed for learning Dijkstra’s shortest path algorithm on Apple iPhone 4 operated on iPhone operating system (iOS), and Acer Inconia Tab operated on an Android operating system. Thirty students, who are either currently studying or had previously studied Computer Networks, were recruited for the usability trial. At the end of each single session, students’ satisfaction interacting with the two mobile devices was measured using QUIS questionnaire. Although there is no significant difference in students’ satisfaction between the two different mobile screen interfaces, the subjective findings indicate that Acer Inconia Tab gained higher scores as compared to Apple iPhone 4.
Investigating Students' Perceptions on Mobile Learning Services
Authors: Almaiah Mohammed Amin , Abdul Jalil Masita
Published: October 2014

M-learning is a form of learning, which has similarities and differences with the electronic learning (e-learning). It is mainly based on the use of the mobile wireless technologies that allow for learners to easily access learning materials anytime he desires and anywhere, whether on campus or off campus. Therefore, this creates a new flexible learning environment in the context of different learning settings. Students' perception of such technology is one of the most important factors for successful adoption of m-learning in the higher education environment. This study is conducted to investigate the perceptions of students in University Malaysia Terengganu (UMT) to move towards applying m-learning in their studies by using their mobile devices and to explore their expectations on mobile learning services. A total number of 91 undergraduate students majoring in computer science participated in the study. The findings show that the students have positive perception towards mobile learning and would like to use their mobile devices for both learning and administrative services.
DAYLIGHT IN A CISTERCIAN HERITAGE CHURCH IN LISBON, FROM RURAL TO URBAN CONTEXT
Authors: Carlos Jorge S. , Martins Ana M.T.
Published: October 2014

Light levels in the churches of the Cistercian Order are mostly related to the fulfilment of liturgical needs. The compound building of Bernardas’ Convent includes a church at the utmost southern corner that dates back to the 17th century. It only has one façade facing due southeast. This paper analyses the relationship between daylight conditions within the building before and after the urbanisation of the surrounding area; taking into account the relationship between the church, its main activities, and solar trajectory. A comparative analysis of the relationship between the actual surrounding context and the initial period after it was built (open field) is given. The highest reflectance of the street canyon has augmented the levels of available daylight.
DEFINING AND DEVELOPING AN ENERGY RETROFITTING APPROACH
Authors: Luther Mark B. , Rajagopalan Priyadarsini
Published: October 2014

This paper identifies the dilemma faced by the stakeholders of existing buildings in regards to a decision making process for energy retrofitting. This paper also identifies the missing stage viewed as the “integrity audit “which can lead to substantial savings in the area of building operation. The methodology is centered on identifying energy waste first, reducing the overall peak electrical demand and then retrofitting for energy-efficiency. A proposed “integrity audit” leads to the classification of three main energy culprits: the identification of waste, missed opportunities, and rescheduling the operation of equipment use. A case study indicating the financial advantages of applying this methodology for a commercial building are presented. The energy retrofitting strategy is divided into two main categories, namely building control improvements and building component implementation. The payback periods are often within months if not immediate.
Wind-Thermal Integrated Power System Scheduling Problem Using Cuckoo Search Algorithm
Authors: Chandrasekaran K. , Simon Sishaj P.
Published: October 2014

A new nature inspired metaheuristic algorithm known as the cuckoo search algorithm (CSA) is presented in this paper, to solve the unit commitment problem (UCP) for hybrid power system. The utilization of wind energy sources is increasing throughout the world. It is therefore important to develop the protocol for the integration of wind generation system with conventional thermal unit generation system. High wind penetration can lead to high-risk level in power system reliability. In order to maintain the system reliability, wind power dispatch is usually restricted and energy storage is considered for smoothing out the fluctuations. On solving UCP, the proposed binary coded CSA finds the ON/OFF status of the generating units while the economic dispatch problem (EDP) is solved using the real coded CSA. The proposed methodology is tested and validated on 3, 4, 9, 12 38 and 100 unit systems for 24 hour scheduling horizon. The effectiveness of the proposed technique is demonstrated by comparing its performance with the other methods reported in the literature.
A Risk-Based Audit Model for Improving the Success Rates of e-Government Project Implementation
Authors: Aikins Stephen K.
Published: October 2014

This study develops a model to help improve the success rates of e-Government projects. In recent years, several e-Government studies have identified many challenges of e-Government initiatives and the critical success factors of such initiatives. Regular audit reviews of project performance provide cost-effective minimization of risks by providing information to management and by helping to take corrective actions in order to ensure a successful project outcome. Despite the potential contributions of audits and risk management to minimize project failure, e-Government and public administration research pay little attention to risk-based project implementation and the specific methods needed to mitigate project challenges. Based on the assumption that project risks are inherent in all phases of the project lifecycle in various dimensions and levels of significance, and that for public sector projects, these risks manifest in four broad categories - stakeholder, institutional, technical and project management risks - the model developed in this research uses a risk-based audit approach to project implementation to provide a comprehensive and methodic tool to systematically improve the success rates of project implementation.
CD28–CD80 Interactions Control Regulatory T Cell Motility and Immunological Synapse Formation
Authors: Thauland Timothy J. , Koguchi Yoshinobu , Dustin Michael L. , Parker David C.
Published: October 2014

Regulatory T cells (Tregs) are essential for tolerance to self and environmental Ags, acting in part by downmodulating costimulatory molecules on the surface of dendritic cells (DCs) and altering naive CD4 T cell–DC interactions. In this study, we show that Tregs form stable conjugates with DCs before, but not after, they decrease surface expression of the costimulatory molecule CD80 on the DCs. We use supported planar bilayers to show that Tregs dramatically slow down but maintain a highly polarized and motile phenotype after recognizing Ag in the absence of costimulation. These motile cells are characterized by distinct accumulations of LFA-1–ICAM-1 in the lamella and TCR-MHC in the uropod, consistent with a motile immunological synapse or “kinapse.” However, in the presence of high, but not low, concentrations of CD80, Tregs form stationary, symmetrical synapses. Using blocking Abs, we show that, whereas CTLA-4 is required for CD80 downmodulation, CD28–CD80 interactions are critical for modulating Treg motility in the presence of Ag. Taken together, these results support the hypothesis that Tregs are tuned to alter their motility depending on costimulatory signals.
A Novel Antibody against Human Factor B that Blocks Formation of the C3bB Proconvertase and Inhibits Complement Activation in Disease Models
Authors: Subías Marta , Tortajada Agustín , Gastoldi Sara , Galbusera Miriam , López-Perrote Andrés , Lopez Lucia de Juana , González-Fernández Fernando Ataúlfo , Villegas-Martínez Ana , Dominguez Mercedes , Llorca Oscar , Noris Marina , Morgan B. Paul , Rodríguez de Córdoba Santiago
Published: October 2014

The alternative pathway (AP) is critical for the efficient activation of complement regardless of the trigger. It is also a major player in pathogenesis, as illustrated by the long list of diseases in which AP activation contributes to pathology. Its relevance to human disease is further emphasized by the high prevalence of pathogenic inherited defects and acquired autoantibodies disrupting components and regulators of the AP C3-convertase. Because pharmacological downmodulation of the AP emerges as a broad-spectrum treatment alternative, there is a powerful interest in developing new molecules to block formation and/or activity of the AP C3-convertase. In this paper, we describe the generation of a novel mAb targeting human factor B (FB). mAb FB48.4.2, recognizing with high affinity an evolutionary-conserved epitope in the Ba fragment of FB, very efficiently inhibited formation of the AP C3-proconvertase by blocking the interaction between FB and C3b. In vitro assays using rabbit and sheep erythrocytes demonstrated that FB28.4.2 was a potent AP inhibitor that blocked complement-mediated hemolysis in several species. Using ex vivo models of disease we demonstrated that FB28.4.2 protected paroxysmal nocturnal hemoglobinuria erythrocytes from complement-mediated hemolysis and inhibited both C3 fragment and C5b-9 deposition on ADP-activated HMEC-1 cells, an experimental model for atypical hemolytic uremic syndrome. Moreover, i.v. injection of FB28.4.2 in rats blocked complement activation in rat serum and prevented the passive induction of experimental autoimmune Myasthenia gravis. As a whole, these data demonstrate the potential value of FB28.4.2 for the treatment of disorders associated with AP complement dysregulation in man and animal models.
Evaluation of the Assessment Plan for Undergraduate Clerkship in Obstetrics and Gynecology, King Abdulaziz University
Authors: Almrstani Ahmad M.S. , Alnoman Abdullah , Abduljabbar Hassan , Sait Hesham , Bazarah Mohammed , Eldeek Basem
Published: October 2014

Background

The standards set by accreditation bodies for student assessment during higher education, such as those of the National Commission for Academic Accreditation & Assessment (NCAAA), are necessary in formulating educational programs. These serve as a benchmark for how colleges or universities are assessed and reflect students' learning. Following the implementation of these guidelines, the Department of Obstetrics and Gynaecology, within the Faculty of Medicine in King Abdulaziz University (KAU), established assessment strategies appropriate to their curriculum, which were valid and reliable, thus enabling students to be fairly assessed throughout their undergraduate course. Since KAU is currently preparing for accreditation by the NCAAA, this study was a necessary undertaking to ensure that the assessment strategies designed by the Department of Obstetrics and Gynaecology are aligned and conform to the NCAAA student assessment guidelines, thereby outlining the standard of expected performance and learning outcomes for students.

Objectives

This study aimed to evaluate the assessment plan of the obstetrics and gynecology clerkship for undergraduate medical students within the Faculty of Medicine, KAU, in comparison to the standard criteria for student assessment as implemented by the NCAAA.

Materials and Methods

A cross-sectional study was conducted, which employed two questionnaires containing questions based on the NCAAA guidelines. The surveys were distributed among the teaching staff and students rotating for 12 weeks within the Department of Obstetrics and Gynaecology, KAU, from September to November 2013. In total, 100/116 (86.2%) students and 26/36 (81.25%) teaching staff participated in the study.

Results

Two sets of results were obtained regarding the student assessment practices in the Department of Obstetrics and Gynaecology, KAU, one from fifth-year medical students and the second from the teaching staff. The results showed that the majority of student respondents agreed that the department conformed to the guidelines and standards as set out by the NCAAA. However, the statistics gathered from the teaching staff participants implied that although the department is adhering to the standards, further improvements are still required in terms of the implementation and design of assessment strategies.

Conclusions

Adherence to the NCAAA student assessment guidelines and its strict implementation are vital to achieving effective learning outcomes among obstetrics and gynecology students. Faculty staff need be appropriately trained in the field of exam preparation and assessment. Further improvements to the existing student assessment strategies used by the Department of Obstetrics and Gynaecology, KAU, are recommended.
Première description d'une pestivirose de l'isard (Rupicapra pyrenaica pyrenaica)
Authors: Alzieu Jean-Pierre , Deplanche M. , Moulignie M. , Letellier Carine , Lacroux C. , Duquesnel R , Baranowski E. , Meyer G. , Kerkhofs P. , Schelcher François
Published: October 2014

Comprendre la circulation de pestivirus chez les ongulés sauvages est potentiellement important pour expliquer les variations d’effectifs dans ces espèces et pour réaliser les programmes de contrôle des pestiviroses atteignant les animaux domestiques. En 2002 dans les Pyrénées ariégeoises, des symptômes d’amyotrophie et d’amaigrissement, associés à des signes d’alopécie bilatérale, avec des zones cutanées glabres et fortement pigmentées sur le chanfrein, le pourtour des yeux et les marges auriculaires ont été observés sur 8 isards (Rupicapra pyrenaica pyrenaica) âgés de 1 à 9 ans, dont 6 avaient été capturés vivants et 2 trouvés morts. Les lésions étaient peu caractéristiques. L’intensité du parasitisme abomasal ou pulmonaire variait d’un individu à l’autre. Un pestivirus a été mis en évidence sur les 6 animaux capturés vivants et un des deux récupérés morts (7 cas sur 8), mais aucun anticorps dirigé contre la protéine NS2/ 3 n’a été trouvé. De nombreuses questions persistent sur la nature transitoire ou persistante de l’infection et sur les modalités de transmission au sein du genre Rupicapra.
La tularémie : situation en France, problématiques et risques en santé publique
Authors: Vaissaire Josée , Mendy Christiane , Le Doujet Claudine , Bedidi-Madani Nora , Le Coustumier Alain , Terrier Marie-Eve , Gaillet Jean-Roch
Published: October 2014

Tularemia : situation in France, issues and public health risk

This is a retrospective study on natural foci of tularemia in animals as well as human cases reported in France between 1999 and 2004. Since 1999, approximately 20 to 60 animals foci of infection in hares are detected every year in 19 to 34 French departments. Human cases often occur in areas where animal foci have erupted, but not always. There are several reasons explaining the presence of this disease on French territory, its underestimation in animals, and probably in man, and its durability. The disease is generally poorly recognised, except amongst shooters who are aware of its existence. Several clinical forms are known in man, sometimes with severe symptoms. The diagnosis of tularemia can be difficult due to its non-specific clinical features. Tularemia is mostly described in hares but other species can be also affected, serving as reservoirs for the infection and sometimes acting as vectors as well. The animal population tested for tularemia should be widened to include other wild species, as well as some of our domestic animals. In man, this diagnosis should be considered in people presenting certain clinical signs. A background on epidemiological data is given. In addition, as Francisella tularensis is one of the bioterrorism agents, it is essential that clinicians and biologists recognise this bacteria and are aware of its dangers. Tularemia was removed from the list of Legally Contagious Disease in veterinary medicine in 1996. It has become a notifiable disease in human medicine in 2002.
Bien-être du porc : le point de vue de l'animal, approches biologiques et comportementales
Authors: Mormède Pierre , Foury Aline , Meunier-Salaün Marie-Christine
Published: October 2014

Le bien-être fait référence à l’état psychologique subjectif de l’individu par rapport à son environnement interne et externe. Puisque nous ne sommes pas encore capables de lire directement les sensations et les émotions de l’animal, nous en sommes réduits à les inférer de l’analyse de leurs manifestations objectives, en particulier physiologiques et comportementales, qui ont été étudiées dans le contexte de la psychobiologie des émotions, du stress et de l’adaptation. L’activation des systèmes neuroendocriniens de réponse au stress (axe corticotrope et système nerveux sympathique) fournissent de nombreux marqueurs pour l’étude des réponses biologiques aux facteurs d’environnement. Cependant leur interprétation en termes de bien-être devra prendre en considération le rôle de ces systèmes dans la physiologie générale de l’organisme. On utilisera aussi des critères comportementaux (analyse du budget-temps et de l’utilisation de l’espace, comportements anormaux, expression des liens sociaux, tests de préférences) qu’il faudra analyser dans le contexte des acquis de l’éthologie appliquée.

RÉSUMÉ
Examen clinique du cheval de saut d'obstacles en situation
Authors: Benoit Philippe
Published: October 2014

Equine veterinarians are frequently asked to evaluate the jumping sport horse during times of competition in order to assess performance issues that a more conventional clinical exam may fail to reveal. Examining a competing horse requires a working knowledge of the discipline, the rules, and technical nature of the jumps themselves. In show jumping, the examiner must understand the level of competition and the ability of the rider in order to accurately assess the condition of the horse. The performance of the horse in competition provides a specialized succession of tests that will help the practitioner to evaluate the horse and appreciate sometimes subtle characteristic changes in attitude around and over the jumps. This observation should be in addition to normal physical and dynamic exams in hand. A possible assessment can be made from videos, observing horses to warm up, and watching the competition.