bluuebunny/crossref_metadata_2025 huggingface dataset:
Tumor Heterogeneity and Post-Irradiation Dysfunction of Endothelium in the Assessment of Response to Treatment in Neuro-Oncology: View of the Problem and Our Practical Experience
Authors: Рудица В.И. , Бондарчук Т.И. , Робак К.О. , Ялынская Т.А. , Земскова О.В. , Главацкий А.Я.
Published: April 2022

Оценка ответа на лечение в нейроонкологии представляет собой сложную задачу, решение которой не всегда возможно даже с помощью наиболее современных методов визуализации. В последнее время наблюдается значительный прогресс в разработке персонифицированных подходов к лечению нейроонкологических пациентов, что требует усовершенствования оценки ответа на лечение. Радиомика является новаторским направлением в диагностических технологиях и основана на применении искусственного интеллекта. К настоящему моменту такие технологии находятся на стадии ранней разработки и крайне ограниченно используются в клинической практике, в то время как перфузионные исследования, позволяющие оценить степень васкуляризации опухоли, получили широкое практическое применение. Несмотря на несомненный прогресс технологических аспектов нейровизуализации, дифференциальная диагностика псевдопрогрессии и опухолевого роста остается краеугольным камнем современной нейроонкологии. Понимание патофизиологических механизмов постлучевых реакций в эндотелии сосудов, углубление знаний относительно биологии опухолей, включая опухолевую гетерогенность, являются необходимым базисом для радиологов, которые занимаются визуализационной оценкой ответа опухоли на лечение. Данная статья демонстрирует взгляд авторов на проблему и собственный практический опыт применения МРТ-перфузии в оценке ответа на лечение в нейроонкологии.

Assessment of response in neuro-oncology is a challenge. The solution isnt easy even with the latest modern visualizing techniques. Recently, much progress has been seen in personalized approaches to the treatment of brain tumors. This demands the improvement of assessment of response to treatment. Radiomics is an emerging field of research, which aims to collect high-dimensional data from clinical images. Nowadays, such technologies are on their early stages of development, and they are limited to use in clinical practice, while perfusion imaging is widely used in clinical practice. In spite of the technological development in neuroradiology, differential diagnostics of tumor progression and pseudoprogression is still a challenge. Understanding the pathological mechanisms of post-irradiation reactions in the endothelium of vessels, increasing knowledge of tumor biology, including tumor heterogeneity are an essential ground for radiologists in assessment of response. This article demonstrates the authors opinion on the problem and their practical experience in the use of MRI perfusion in the assessment of response in neuro-oncology.
Transpupillary Thermotherapy in Treatment of Retinoblastoma
Authors: Макаревич О.О.
Published: April 2022

В последние десятилетия акцент в менеджменте пациентов, страдающих ретинобластомой, сместился с частого использования дистанционной лучевой терапии к широкому применению цитостатических препаратов и локальных методов лечения. Данная стратегия реализуется с целью уменьшения возникновения вторых злокачественных опухолей у данной категории пациентов, особенно это актуально при наличии наследственной ретинобластомы. В распоряжении специалистов, занимающихся лечением ретинобластомы, есть такие методы лечения, как системная и интраартериальная химиотерапия, криодеструкция опухолей, лазерная коагуляция, транспупиллярная термотерапия и др. Термотерапия метод подведения тепловой энергии к тканям для локального повышения температуры, достигающей цитотоксического уровня, что в свою очередь приводит к разрушению области, которая подвергается облучению. Термотерапия может реализовываться посредством различных приборов, в том числе ультразвуковых, микроволновых, инфракрасных устройств. Лазер-индуцированная термотерапия это минимально инвазивный метод лечения опухолей различных локализаций. Транспупиллярная термотерапия это метод гипертермии посредством использования инфракрасного излучения диодного лазера. Данный метод особенно эффективен в лечении ретинобластом небольших размеров. Однако до настоящего времени нет единых алгоритмов применения данного метода у пациентов с ретинобластомой.

The emphasis in the management of retinoblastoma has shifted in recent years from the frequent use of external beam radiation therapy to the widespread implementation of chemoreduction and focal therapy. This treatment strategy has been used as a way to decrease the incidence of second malignancies in children with germinal retinoblastoma. Specialists use various techniques, including systemic and periocular chemotherapy, intraarterial chemotherapy, plaque radiotherapy, laser photocoagulation, cryotherapy, and thermotherapy. Thermotherapy is a method of delivering heat to tissue to raise local temperature to cytotoxic levels, leading to tissue death. Thermotherapy can be generated with ultrasound, infrared radiation, microwave devices, and other methods. Laser-induced interstitial thermotherapy is a minimally invasive treatment for tumors in the brain, prostate, liver, and eye. Transpupillary thermotherapy is a specific form of ocular thermotherapy using infrared radiation (diode laser). It has been the most effective for small retinoblastomas. However, there are no common techniques for this method.
Chlamydial Pneumonia in Children
Authors: Романовская О.Ф. , Романова О.Н.
Published: April 2022

Представлен обзор литературы по этиологии, эпидемиологии, патогенезу, клиническим проявлениям, диагностике и лечению хламидийной пневмонии у детей.

The article is dedicated to a review of the etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment of chlamydial pneumonia in children based on the сontemporary literature data.
Generalized Infection Сaused by Yersinia Enterocolitica in an Adolescent: a Case Report
Authors: Романовская О.Ф. , Адамович О.Л. , Романова О.Н.
Published: April 2022

Иерсиниозная инфекция встречается повсеместно и остается третьей наиболее распространенной причиной бактериального зооноза пищевого происхождения в Европе. Клиническая картина иерсиниозной инфекции очень разнообразна. Иерсиниоз может проявляться неспецифическими симптомами, напоминающими другие заболевания: острую ревматическую лихорадку, системные заболевания соединительной ткани, туберкулез, злокачественные новообразования и др. В ряде случаев остается нераспознанным. Описан клинический случай генерализованной формы иерсиниозной инфекции у подростка, сопровождавшейся выраженным интоксикационным и нейромиалгическим синдромом при минимальных локальных проявлениях. Представлены результаты лабораторных и инструментальных методов обследования пациента в динамике.

Yersinia infection is ubiquitous and remains the third most common cause of foodborne bacterial zoonosis in Europe. The clinical presentation of Yersinia infection is very diverse. Yersiniosis can manifest with non-specific symptoms resembling other diseases: acute rheumatic fever, systemic connective tissue diseases, tuberculosis, malignant neoplasms, etc. In some cases it remains unrecognized. The case report of the generalized form of Yersinia infection in an adolescent, accompanied by prominent intoxication and neuromialgic syndrome with minimal local manifestations is described. The results of laboratory and instrumental examination of the patient in the course of disease are presented.
Measles in a Vaccinated Patient
Authors: Ластовка И.Н. , Артемчик Т.А. , Трубчик О.Н.
Published: April 2022

Корь высококонтагиозное, острое вирусное заболевание, которое может привести к та- ким осложнениям, как пневмония, энцефалит, вплоть до летального исхода. В результате вы- сокого охвата 2-дозной вакцинацией против кори в нашем регионе сохраняется относитель- но благоприятная эпидемиологическая ситуация. Регистрация кори в Республике Беларусь связана с завозными случаями из других стран, где корь остается эндемичной. Не исключены в данной ситуации и случаи возникновения кори у иммунизированных пациентов. В статье представлен клинический случай заболевания корью у вакцинированного пациента.

Measles is a highly contagious, acute viral illness that can lead to complications such as pneumonia, encephalitis, and death. As a result of high 2-dose measles vaccination coverage in the Belarus and the high control of measles in our region, a relatively favorable measles situation remains. Nevertheless, the import of cases from other countries where measles remains endemic continues to occur, which leads to the emergence of groups of cases in Belarus. Cases of measles, even in vaccinated patients, are not excluded in this situation. The article presents a clinical case of measles in a vaccinated patient.
Ixodic Tick-Borne Borreliosis: Problems of Clinical Diagnostics in Children
Authors: Довнар-Запольская О.Н. , Чижевская И.Д. , Шеремет А.Н.
Published: April 2022

В настоящее время, несмотря на кажущуюся простоту диагностики иксодового клещевого боррелиоза, имеются определенные трудности при постановке диагноза. Это связано прежде всего с полиморфизмом клинических проявлений болезни Лайма. В статье представлены осо- бенности клиники различных стадий иксодового клещевого боррелиоза у детей, представляющих наибольшие трудности для педиатров.

Currently, there are still some difficulties of establishing the diagnosis of ixodid tick-borne borreliosis in children. This is due to polymorphism of the clinical manifestations of Lyme disease. The article introduces some particularities of various clinical stages of ixodic tick-borne borreliosis in children, which present the most difficulties for pediatricians
Some Results of Studying the Efficiency of Vaccination Against Hepatitis B in the Republic of Belarus
Authors: Высоцкая В.С. , Коломиец Н.Д. , Глинская И.Н. , Василевская А.Е. , Романова О.Н.
Published: April 2022

Цель. Предварительное изучение распространенности маркеров гепатита В и эффективности вакцинации против вируса гепатита В (hepatitis B virus – HBV) в отдельных группах условно здорового населения Республики Беларусь.Материалы и методы. Проведены оценка наличия протективного иммунного ответа к HBV путем определения антител к его поверхностному белку HBs-антигену (anti-HBs), а также исследование на наличие суммарных антител к HB-core антигену HBV (anti-HBc) как косвенного маркера контакта пациента с вирусом. Серопротективной концентрацией anti-HBs в сыворотке крови считали 10 мМЕ/мл и выше (ИФА, тестсистемы производства АО «Вектор-Бест» (Российская Федерация)).Результаты. Полный курс вакцинации против гепатита В обеспечивает формирование протективного иммунитета у 84,38% обследованных лиц. Доля серопозитивных лиц сокращается с увеличением времени, прошедшего после завершения вакцинации. Результаты исследования демонстрируют наличие 19,61% серонегативных лиц из числа обследованных через 10 и более лет после последней введенной дозы вакцины. Обследование 288 лиц с отрицательным результатом наличия HBsAg выявило 52 человек – 18,06%, имеющих anti-HBc.Заключение. В целях оценки и контроля эффективности проводимой вакцинации против HBV целесообразны формирование и внедрение вакцинального серологического аудита в группах риска и оптимизация тактики вакцинации взрослых лиц.

Purpose. Preliminary study of the prevalence of hepatitis B markers and the effectiveness of hepatitis virus (HBV) vaccination in certain groups of conditionally healthy population of the Republic of Belarus.Materials and methods. The presence of a protective immune response to hepatitis B virus was evaluated by determination of antibodies to the surface antigen of HB virus (anti-HBs), as well as a study for the presence of total antibodies to the HB-core antigen of HB virus (anti-HBc), as an indirect marker of patient’s contact with HB virus. Seroprotective concentration of specific antibodies in blood serum was considered to be 10 mIU/ml and higher (IFA, test systems manufactured by Vector Best JSC (Russian Federation)).Results. The full course of hepatitis B vaccination ensures the formation of protective immunity in 84.38% of the examined persons. The proportion of seropositive individuals decreases with the increase in the time elapsed after the completion of vaccination. The study results demonstrate the presence of 19.61% of seronegative individuals examined 10 years or more after the last vaccine dose administered. A survey of 288 people with a negative result of HBsAg revealed 52 people – 18.06% with anti-HBc.Conclusion. In order to assess and monitor the effectiveness of vaccinations against HV, it is advisable to form and implement a vaccine serological audit in "risk groups" and optimize the vaccination tactics of adults.
Child with COVID-19: Nutrition in the Intensive Care Unit
Authors: Ненартович И.А. , Голобородько Н.В. , Почкайло А.С.
Published: April 2022

С развитием пандемии COVID-19 растет вовлечение в нее детей (>10% от заболевших), по крайней мере у 4% детей заболевание протекает тяжело. Разработаны и продолжают совершенствоваться подходы к фармакотерапии этого заболевания. Мальнутриция выявляется примерно у 53% детей, поступающих в отделение интенсивной терапии с различными заболеваниями. Недостаточность питания ассоциирована с ростом смертности, удлинением сроков пребывания в отделении интенсивной терапии и продолжительности искусственной вентиляции легких у детей с различными нозологиями. С неблагоприятным прогнозом COVID-19 у детей ассоциированы врожденные пороки сердца, бронхолегочная дисплазия, неврологические заболевания, ожирение, мультисистемный воспалительный синдром, одышка, острый респираторный дистресс-синдром, острое почечное повреждение, повышение уровня С-реактивного белка и D-димеров, активности лактатдегидрогеназы. В обзоре приведены рекомендации по нутритивной поддержке ребенка с COVID-19 в условиях отделения интенсивной терапии: общая стратегия, пошаговый алгоритм, расчет калоража, потребности в белке, дотация цинка, витаминов, липидов, скрининг и профилактика синдрома возобновленного питания.

The share of the child population accounts for >10% of all patients with COVID-19, 4% of them have a severe disease. Approaches to pharmacotherapy of this disease have been developed and continue to be improved. Malnutrition is detected in approximately 53% of children admitted to the intensive care unit with various diseases. Malnutrition is associated with an increase in mortality, lengthening of stay in the intensive care unit and the duration of mechanical ventilation of children with different diseases. Congenital heart disease, chronic pulmonary disease, neurological diseases, obesity, multisystem inflammatory syndrome, acute respiratory distress syndrome, acute kidney injury, gastrointestinal symptoms, elevated CRP, D-dimer, lactate dehydrogenase are associated with unfavorable prognosis in children with COVID-19. The review includes recommendations on child with COVID-19 nutrition in intensive care unit: a general strategy, a step-by-step algorithm, evaluation of energy, protein, zinc, vitamins, lipids and re-feeding syndrome screening and prevention as well.
Military Conflicts and Infectious Diseases
Authors: Голубовская О.А. , Шкурба А.В.
Published: April 2022

В предлагаемом материале показано, что военные конфликты являются причиной появления различных инфекционных болезней, причем последние могут иметь гораздо более масштабное поражение, чем сами военные действия. А во время пандемии COVID-19 возрастает риск быстрого распространения коронавирусной инфекции, в т. ч. и ее тяжелых форм, ввиду отсутствия должного доступа к своевременной медицинской помощи.

The proposed material shows that military conflicts are the cause of the emergence of various infectious diseases, and the latter can have a much larger defeat than the hostilities themselves. And during the COVID-19 pandemic, the risk of a rapid spread of coronavirus infection, including its severe forms, increases due to the lack of proper access to timely medical care.
Neuromyelitis Optica Spectrum Disorders: Terminology, Diagnostic Difficulties, Polymorbidity
Authors: Лурье Т.В. , Федулов А.С. , Дрик О.Н.
Published: April 2022

Заболевания спектра оптиконейромиелита (ЗСОНМ) – это группа аутоиммунных воспалительных состояний, сопровождающихся поражением центральной нервной системы, распространенной иммуноопосредованной астроцитопатией и вторичной демиелинизацией, аксональным повреждением, вовлекающим преимущественно зрительные нервы, спинной мозг, area postrema. Основной мишенью для воспаления является аквапорин-4, образующий водные каналы, обнаруженный на отростках астроцитов.Коморбидность ЗСОНМ и синдрома Шегрена, как и других аутоиммунных заболеваний, является малоизученной проблемой. Вопросы патогенетической связи заболеваний, а также своевременной диагностики, особенностей течения и терапевтических подходов в случае их сочетания являются наиболее актуальными. В работе представлены обзор состояния вопроса терминологии, клиники, диагностики и лечения, полиморбидности ЗСОНМ, а также клинический случай сосуществования ЗСОНМ, отвечающего всем диагностическим критериям, включая наличие антител к аквапорину-4 в сыворотке крови, и синдрома Шегрена.

Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory conditions accompanied by damage to the central nervous system, widespread immune-mediated astrocytopathy and secondary demyelination, axonal damage involving mainly the optic nerves, spinal cord, area postrema. The primary target for inflammation is aquaporin-4, which forms water channels found on the foot processes of astrocytes.The comorbidity of NMOSD and Sjogren’s syndrome, like other autoimmune diseases, is a little-studied problem. The issues of the pathogenetic connection of diseases, as well as timely diagnosis, features of the course and therapeutic approaches in the case of their combination are the most relevant. The paper presents an overview of the state of the issue of terminology, clinic, diagnosis and treatment, comorbidity of NMOSD, as well as a clinical case of the co-existence of NMOSD that meets all diagnostic criteria, including the presence of antibodies to aquaporin-4 in the blood serum and Sjogren’s syndrome.The dramatic effect of mitoxantrone is shown. The pathogenesis, symptoms and management of NO and clinically similar diseases are reviewed.
ENDÜSTRİYEL ÇEVİK İŞLETME İÇİN DENGELENMİŞ BAŞARI GÖSTERGELERİ
Authors: ÇELİKDİN Alperen Ekrem
Published: April 2022

Durumsallık yaklaşımı ile başlayıp, kompleksite, kaos ve karmaşıklık kuramlarına uzanan, küreselleşme ve Endüstri 4.0 kavramları ile işletmelerde vücut bulan dinamik rekabet unsurları, yıkıcı inovasyon yaklaşımları ile birlikte işletmeleri hiç olmadığı kadar tehdit etmektedir. Yoğunlukla üretim ve yazılım alanlarında doksanlı yıllarda ortaya çıkan çeviklik kavramının, günümüzde endüstriyel işletmelerin faaliyet gösterdikleri sektörlerden bağımsız olarak, yapı, süreç ve stratejilerine göre uyarlanması ve kazanılması zorunlu olan bir yetenek hâline gelmiştir. Çalışmada örgütsel çeviklik kavramı, mümkün kılan destekleyiciler ve gerekli olan yetenekler bağlamında kapsamlı olarak incelenmiştir. Kaplan & Norton tarafından geliştirilmiş olan Dengeli Başarı Göstergesi çerçevesinde işletmelerin mevcut strateji ölçütlerine boyutsal olarak ilave edilebilecek bir yönetim aracı olarak özetlenmeye çalışılmıştır. İleride yapılabilecek çalışmalarla bu ölçütleri uygulayan ve uygulamayan işletmeler mukayese edilerek, çerçevenin tutarlılığı ölçülebilecektir.
TEKSTİL SEKTÖRÜNDE ÜRETİM YAPAN FİRMALARIN PAZAR PERFORMANSLARINDA JENERİK STRATEJİLERİN ETKİSİ
Authors: ÇELİK Tarik Ziyad , YILDIRIM Yusuf Ozan
Published: April 2022

Gelişmekte olan ülkelerdeki üretim firmalarında rekabetin yoğun olduğu ve rekabetin sonucu olarak firmaların maliyet baskısı ile hareket ettikleri bilinmektedir. Firmalar faaliyet gösterdikleri rekabet ortamını inceleyerek en uygun stratejiler için karar vermelidir. Stratejilerin sektörel uyumluluğunun incelendiği araştırmalarda, bazı sektörlerde genel kabul görmüş stratejiler olduğu da bilinmektedir. Pandemi döneminde firmalar büyük bir değişim ve dönüşüm geçirmek zorunda kalmıştır. Değişen beklenti, ihtiyaç ve istekler firmaları daha esnek olmaya zorlarken, firmaların faaliyetlerine devam edebilmesi için uygun stratejinin ne olduğu araştırılması gereken bir konudur. Bu sebeple gerçekleştirilen ampirik çalışma, Türkiye’nin lokomotif sektörlerinden biri olan tekstil sektöründe firmaların pazar performansı açısından hangi jenerik stratejinin daha etkili olduğunu belirlemek ve mevcut durumun ne olduğuna yönelik bir çıkarım yapmayı amaçlamaktadır. Araştırmanın amacına yönelik geliştirilen model sonrası hazırlanan anket formu araştırmanın evreninini temsil edebilecek Güneydoğu Anadolu Bölgesi’nde faaliyet gösteren 120 tekstil firmasına gönderilmiştir. Anketlere dönüşler sonrası elde edilen 80 anket üzerinden araştırma hipotezleri test edilmiştir. Sonuç olarak tekstil sektöründe jenerik stratejilerden maliyet liderliği stratejisinin pazar performansına etkisi bulunamamış, farklılaştırma stratejisinin ise pazar performansını olumlu yönde etkilediğine ulaşılmıştır. Son olarak tekstildeki alt dallar incelendiğinde, maliyet liderliği, farklılaştırma ve pazar performansı ortalamalarının en düşük olduğu alt dalın “konfeksiyon”, en yüksek olduğu alt dalın ise “teknik tekstil” olduğu görülmektedir
Analisis Kunjungan Wisatawan Mancanegara melalui Pintu Udara, Laut dan Darat
Authors: Alkautsar Muhammad Ammar , Sely Sekar Anisa , K.S Della Najunda , Fadhillah Rofi Ilmi , Lazuardi Alfredo Edward , Muliawati Triyana
Published: April 2022

In early 2020 the COVID-19 outbreak had entered the territory of Indonesia so a lockdown system began to be implemented in several areas to overcome the spread of the Covid-19 outbreak, including on the tourist arrivals route through land gates, air gates, and sea gates. This makes the writer interested in seeing the number of foreign tourists entering Indonesia through land, sea, and air gates in the hope of helping the government in increasing the number of foreign tourists visiting Indonesia by optimizing the facilities and infrastructure on the tourist arrivals route. In this study, the authors looked at the effect on the entrance data of foreign tourists and the trends or changes that existed in the data held. The research was conducted by applying the Kruskal-Wallis test to see the relationship between the entry pathways and the Cox-Stuart test to see changes in the data. These two tests are used because they are following the objectives and existing research data. After the tests were carried out, the results showed that there was a difference between the entry routes, and it was seen that the data had decreased, one of the contributing factors was the PSBB (Large-Scale Social Restrictions) due to the Covid-19 pandemic.
School-Based Management Committees (SBMCs) and How to Study Them: A Methodological Review of a RISE Research Project
Authors: Ogwuike C. Obinna , Nweke Emeka W.
Published: April 2022

In this Insight Note, the authors provide a detailed explanation of our research strategy and the methodologies and tools we are using to assess the institutional norms and conditions that lead to effective SBMCs. The goal of the note is to show other researchers interested in Nigeria’s SBMCs the type of work we are doing, and exactly how our research team operates in rural Nigeria. The authors hope that this information will be useful to researchers interested in studying Nigeria’s SBMCs, or in the nuances of data collection in rural Nigeria generally.
Studi Karakteristik Pengendara Sepeda Motor dan Penggunaan Helm di Kabupaten Kuantan Singingi
Authors: Sudastin Jennyfer , Alwinda Yosi , Sebayang Mardani
Published: April 2022

Penggunaan helm menjadi suatu hal yang sangat penting dalam berkendara, karena dengan menggunakan helm, kefatalan akibat suatu kecelakaan dalam berkendara dapat diminimalisir, serta melindungi kepala dari benturan saat terjadinya kecelakaan. Penelitian inibertujuanuntuk mengetahui bagaimana volume lalu lintas serta perilaku pengendara dan karakteristik pengendara sepeda motor di Kabupaten Kuantan Singingi. Metode yang digunakan pada penelitian ini menggunakan metode analisis deskriptif dalam menganalisis data. Pengambilan data dilakukan dengan pengamatan (survei) langsung di ruas jalan Nasional di Kabupaten Kuantan Singingi (Jln. Perintis Kemerdekaan, jln. Ahmad Yani, jln. Diponegoro, jln. Tuanku Tambusai dan jln Proklamasi). Dari hasil penelitian ini, diperoleh volume dan karakteristik pengendara sepeda motor di kabupaten Kuantan singing. Kesimpulan dari penelitian ini yaitu perilaku pengendara sepeda motor tertinggi di Kabupaten Kuantan Singingi terjadi pada jam 16:00-17:00 WIB yaitu pada pengemudi yang menggunakan helm (berkendara sendiri) dengan jumlah 242 kend/jam. Hal ini disebabkan pengendara sepeda motor pada jam tersebut sudah taat dalam menggunakan helm. Selain itu diperoleh juga perilaku pengendara sepeda motor terendah pada jam 10:00-11:00 WIB dengan jumlah 169 kend/jam pada pengemudi yang menggunakan helm (berkendara sendiri). Hal ini disebabkan karena pengendara sepeda motor pada jam tersebut masih banyak yang melakukan aktifitas didalam ruangan. Volume pengendara sepeda motor tertinggi di Kabupaten Kuantan Singingi terjadi pada hari Minggu di jam 16:00-17:00 dengan jumlah 825 kend/jam, volume pengendara sepeda motor terendah di terjadi pada hari Rabu pada jam 11:00-12:00 dengan jumlah sepeda motor 478 kend/jam. Volume rata rata tertinggi terjadi pada jam sibuk yaitu pada jam 07:00-08:00, 09:00-10:00, 14:00-15:00 dan jam 16:00-17:00.
Pengaruh Penggunaan Styrene Butadiene Rubber Latex Terhadap Kuat Tekan Bata Ringan
Authors: Monica Tiara , Suryanita Reni , Maizir Harnedi
Published: April 2022

Bata ringan merupakan bata yang memiliki berat isi berkisar antara 400 kg/m3 hingga 1.400 kg/m3. Bata ringan digunakan sebagai alternatif untuk dinding bangunan. Keunggulan dari penggunaan bata ringan adalah hemat biaya, mudah dikerjakan, tahan terhadap panas, tahan rembesan, kedap suara serta tidak terlalu membebani struktur di bawahnya. Salah satu tujuan perkembangan bata ringan untuk meningkatkan ketahanan terhadap retak. Bahan tambah yang digunakan untuk mengatasi masalah keretakan bata ringan pada penelitian ini yaitu Styrene Butadiene Rubber (SBR) Latex. SBR Latex merupakan karet sintetis yang dapat menambah kekuatan ikatan antara pasta dengan agregat maupun antar agregat, sehingga dapat meningkatkan kualitas dan kuat tekan dari bata ringan. Penelitian bertujuan untuk menganalisis pengaruh penggunaan bahan tambah SBR Latex terhadap nilai kuat tekan bata ringan. Pasir yang digunakan berasal  dari pasir Teratak Buluh, Kabupaten Kampar. Benda uji  dibuat berukuran panjang 10 cm, lebar 10 cm, tinggi 10 cm dengan variasi penambahan SBR Latex yaitu 0%, 0,5%, 1,0%, 1,5%, 2,0%, 2,5% terhadap berat semen. Benda uji dibuat sebanyak 36 sampel. Tahap awal yang dilakukan adalah pengujian karakteristik agregat halus, mix design, pembuatan dan perawatan benda uji. Pengujian kuat tekan dilakukan pada umur 3, 7 dan 28 hari. Berdasarkan hasil pengujian, nilai kuat tekan bata ringan 0% SBR Latex bernilai 1,05 Mpa sedangkan untuk variasi optimum bata ringan ada pada campuran SBR Latex 1,5% dengan nilai kuat tekan 1,31 Mpa.  Sehingga disimpulkan bahwa penambahan SBR Latex dapat meningkatkan kuat tekan bata ringan. Dengan demikian penggunaan SBR Latex dalam campuran bata ringan dapat diterapkan oleh produsen bata ringan dan menjadi referensi untuk penelitian selanjutnya.
Pengaruh Penggunaan Hidrogen Peroksida Terhadap Kuat Tekan Bata Ringan
Authors: Rumiati Maya , Suryanita Reni , Maizir Harnedi
Published: April 2022

Kebutuhan bata yang terus meningkat membuat banyak alternatif pengganti bata yaitu bata ringan. Bata ringan merupakan inovasi dari bata konvensional yang memiliki densitas lebih ringan. Bata ringan dibuat dengan memasukkan gelembung-gelembung udara ke campuran semen saat proses pembuatan pasta semen sehingga menjadi lebih ringan dari pada bata konvensional oleh karena itu bata ringan banyak digunakan pada bangunan tinggi. Penambahan Hidrogen Peroksida (H2O2) dapat membuat busa sehingga dapat meringankan densitas bata ringan. Penelitian ini bertujuan untuk menganalisis kuat tekan bata ringan serta membandingkan keefektifan dengan atau tanpa penambahan H2O2 pada pembuatan bata ringan. Adapun pasir yang digunakan yaitu pasir Teratak Buluh, Kabupaten Kampar, Riau. Benda uji dibuat dalam spesifikasi ukuran kubus dengan sisi 10 cm. Dilakukan variasi penambahan H2O2 0%; 0,5%; 1,0%; 1,5%; 2,0% dan 2,5% terhadap berat semen. Sebelum dimulai pembuatan benda uji terlebih dahulu dilakukan pengujian karakteristik agregat halus lalu dibuat job mix design, setelah itu maka dapat dilakukan pembuatan dan perawatan benda uji dengan jumlah total 36 benda uji. Selanjutnya dilakukan pengujian kuat tekan pada umur 3 hari,7 hari dan 28 hari. Hasil penelitian ini menunjukkan kuat tekan optimum didapatkan pada variasi 1,0% yaitu 1,185 MPa. Berdasarkan penelitian ini dapat disimpulkan bahwa dengan penambahan H2O2 dapat meningkatkan kuat tekan pada bata ringan sebesar 13,5%.
Studi Peluang Pengendara Sepeda Motor dalam Penggunaan Helm di Kabupaten Kuantan Singingi
Authors: Alwinda Yosi , Sebayang Mardani , Hamdi Rhoma Putra Benny , Sudastin Jennyfer
Published: April 2022

Helm merupakan hal yang sangat penting dipergunakan dalam berkendaraan sepeda motor. Penggunaan helm akan mengurangi tingkat kefatalan akibat kecelakaan dalam berkendara, karena fungsi helm melindungi kepala dari benturan saat terjadinya kecelakaan. Penelitian ini bertujuan untuk mengetahui peluang pengendara sepeda motor dalam penggunaan helm di Kabupaten Kuantan Singingi. Metode yang dipergunakan pada penelitian ini adalah metode analisis deskriptif dan analisis regresi logistik. Pengambilan data dilakukan dengan pengamatan (survei) langsung dan melakukan wawancara kuesioner kepada sampel pengguna sepeda motor di ruas Jalan Nasional di Kabupaten Kuantan Singingi (Jalan Perintis Kemerdekaan, Jalan Ahmad Yani, Jalan Diponegoro, Jalan Tuanku Tambusai dan Jalan  Proklamasi). Dari hasil penelitian ini, diperoleh peluang penggunaan helm di Kabupaten Kuantan Singing. Berdasarkan karakteristik dan peluang pengendara sepeda motor dari 14 variabel didapatkan yang memiliki hubungan dengan penggunaan helm terdiri dari 7 variabel. Variabel-variabel tersebut adalah: usia (umur), pendidikan, jumlah penumpang, gambaran kepatuhan, menggunakan helm, tali pengikat helm serta cedera kepala. Dari analisis  diperoleh pengendara sepeda motor yang lewat di Jalan Nasional yang masuk ke daerah perkotaan di Kabupaten Kuantan Singingi termasuk kategori taat dalam aturan menggunakan helm saat berkendaraan di jalan raya.
Pemetaan Salinitas Sumur Dangkal Berdasarkan Jumlah Konsentrasi Garam Di Kecamatan Tebing Tinggi Dan Tebing Tinggi Barat Kabupaten Kepulauan Meranti
Authors: Annam M. Khairul , Handayani Yohanna Lilis , Darmayanti Lita
Published: April 2022

This study was conducted to analyze the salinity of shallow well water so as to get an overview of the distribution of groundwater salinity at the research location. The research location is in the Selatpanjang City area, precisely in the Tebing Tinggi District and part of the Tebing Tinggi Barat District, Meranti Islands Regency. The research site is surrounded by the sea and rivers. Many people in the research location live in coastal areas. In coastal areas or near bodies of water, tidal water can enter up to the ground level and even onto roads. This situation makes people think that their groundwater is polluted due to tidal water entering the mainland. This research can provide information to the government and the community at the research site regarding the distribution of groundwater salinity that has occurred. The data analysis used is the interpolation method by creating a mapping using the ArcGIS application. Data analysis can be done after getting the data from the salinity measurement in the field. The water quality test parameters reviewed in this study were the salinity value of shallow wells water measured with a refractometer and marked the coordinates of the sample using the Avenza Maps application. In this study, 57 shallow wells were taken randomly. The results of field measurements show that based on salt concentration, shallow well water is classified as dubious and dangerous.
REPRODUCTIVE QUALITIES OF COWS OF THE YAROSLAVL BREED
Authors: Давыдова А.С. , Федосенко Е.Г.
Published: April 2022

Представлены данные научных исследований воспроизводительной способности крупного рогатого скота в зависимости от уровня молочной продуктивности и возраста первого отёла. Исследования проведены в условиях племенного завода по разведению ярославской породы, расположенного в Ивановской области. Установлено, что уровень молочной продуктивности оказывает определённое влияние на показатели воспроизводства стада. С повышением молочной продуктивности увеличивается число коров с гинекологическими заболеваниями, растёт индекс осеменения, снижается коэффициент воспроизводительной способности и удлиняется сервис-период. У первотёлок он составил 131,5 дня, у полновозрастных коров – 128,2 дня, индекс осеменения с возрастом повысился с 1,47 до 1,73. Снизилась доля коров, оплодотворившихся от первого осеменения, с 70,8% по первой лактации до 53,3% у коров третьей лактации. Коровы, осеменённые и отелившиеся в более раннем возрасте, в 88,7% случаев оплодотворялись в первую охоту. Средний индекс осеменения у них составил 1,11, что на 0,94 единицы меньше, чем у коров, отелившихся в возрасте 26–30 месяцев. Сервис-период находился в пределах нормы только у коров первой лактации с удоем до 4000 кг молока и составил в среднем 75,9 дней. У коров с удоем более 6000 кг молока сервис-период был на уровне 159,4 дней, что на 83,5 дня больше, чем у животных с меньшей продуктивностью.

The data of scientific studies of reproductive ability of cattle depending on the level of milk producing ability and age of the first calving are presented. The researches were carried out in the conditions of a breeding farm for breeding the Yaroslavl breed located in the Ivanovo region. It has been established that the level of milk producing ability has a certain effect on the reproduction rates of the herd. With an increase in milk producing ability the number of cows with gynecological diseases increases, the insemination index grows, the coefficient of reproductive ability decreases and the service period extends. In the first-calf heifers it amounted to 131.5 days, in mature cowbanes – 128.2 days, the insemination index with age increased from 1.47 to 1.73. The proportion of cows fertilized from the first insemination decreased from 70.8% for the first lactation to 53.3% in cows of the third lactation. Cows inseminated and calved at an earlier age in 88.7% of cases were fertilized in the first heat. Their average insemination index was 1.11, which is 0.94 units less than in cows calved at the age of 26–30 months. The service period was within the norm only in cows of the first lactation with a milk yield up to 4000 kg and averaged 75.9 days. Cows with more than 6,000 kg of milk had a service period of 159.4 days, which is 83.5 days more than animals with less productivity.
Research on Coordinated Evolution of Economic and Logistics Coupling in Yangtze River Delta Region
Authors: Ren Qilong , Zhou Jinbo , Yang Jing , Wu Menglu , Mao Guangxiong
Published: April 2022

Two subsystems in the economy and logistics are proposed to establish a comprehensive evaluation index system by using principal component analysis and the comprehensive weighted method. For 41 cities of the Yangtze River Delta cities, the economic development and the comprehensive score of the logistics system in 2003, 2008, 2013, 2017 are calculated, and through the analysis of the coupling coordination model, the economic system and coupling coordination degree of the temporal and spatial evolution process of the logistics system are investigated. The results show that the coupling coordination degree in the Yangtze River Delta region decreases gradually from the eastern coastal areas to the inland areas, and the coupling coordination degree is polarized in space.
Spatial Differentiation of Regional Innovation Capacity in Jiangsu, China
Authors: Wu Fan , Xu Haiying , Lu Xinyi
Published: April 2022

This article addresses regional innovation capacity as an important driver of regional economic growth and a way to achieve coordinated regional development. With the number of patents as the index of innovation capacity measurement and the data from the Statistical Yearbooks from 2008 to 2017, we explore the spatial differentiation of innovation capacity in Jiangsu, China. Spatial clustering analysis and spatial autocorrelation analysis are used for this research. The result shows that the innovation capacity of 13 cities in Jiangsu is categorized into four levels. The gradient innovation capacity is weakened significantly from the south to the north in space. Jiangsu province has the distribution of regional innovation capacity level as the characteristics of spatial agglomeration. However, the province also has the characteristics of stage evolution, which shows the trend of aggregation, dispersion, and reagglomeration. The research results have important implications for optimizing the regional innovation system in Jiangsu Province.
Evaluation of Green Logistics Development in Fujian, China
Authors: You Junxiong , Sho Yingyu
Published: April 2022

Green logistics has become important in the development of China's logistics industry, and the evaluation and monitoring of the development of green logistics have attracted much research interest. Green logistics is closely related to the overall logistics development based on the awareness of sustainable development. Taking Fujian Province as an example, we construct the evaluation index system of logistics development to evaluate the results of green development. After standardizing and dimensioning the evaluation index data with SPSS, the score of logistics development level in Fujian from 2014 to 2019 is obtained by using principal component analysis, and the development of green logistics in the region is evaluated based on the proportion of energy consumption of logistics industry during this period. The results show that the development of green logistics in this region is in a good direction, and the logistics industry presents sustainable development.
Spatial and Temporal Characteristics and Driving Force Analysis of Cropland Change: Taking Dangyang City, Yichang City as Example
Authors: Xu Lei , Wang Heng , Lu Changliang
Published: April 2022

With the land use data of Dangyang City, Yichang City, Hubei Province in 2000, 2010, and 2020, 13 factors of nature, economy, and society were selected as the driving factors affecting the change of Cropland by using the land-use transition matrix and the kernel density analysis. In this study, the dynamic degree model of cropland use was introduced, combined with the geographic detector method, to explore the spatiotemporal variation characteristics and main driving factors of cropland in various towns in Dangyang City from 2000 to 2020. The results showed that the distribution of cropland generally showed a decreasing trend from southeast to northwest. From 2010 to 2020, the cropland in Dangyang City changed significantly, and the cropland area decreased. Economic and social factors turn out to be the main factors affecting the distribution of cropland. When interacting with other factors, the impact on cropland is weakened, and natural factors have interactive effects on cropland.
Instytucje państwa polskiego wobec zagrożeń wywołanych przez epidemię COVID-19
Authors: Włodarczyk Bartosz
Published: April 2022

Administracja publiczna pełni nadrzędną rolę w kontekście kreowania bezpieczeństwa wewnętrznego państwa. Charakterystyka występujących zagrożeń przyczynia się do powstawania ciągłej potrzeby redefiniowania pojęć oraz wypracowywania nowych mechanizmów. Zagadnienia związane z początkiem epidemii COVID-19 oraz intensyfikacją pierwszej fali zachorowań wzmagają potrzebę zrozumienia funkcji instytucji państwowych w strukturze bezpieczeństwa wewnętrznego Polski. Dodatkowo, przedstawiona w treści pracy ankieta badawcza podejmuje wyzwanie zobrazowania nastrojów społecznych, które kształtowały się w trakcie pierwszej fali zachorowań. Niniejszy artykuł stanowi próbę przeanalizowania sprawczości instrumentów państwowych w obszarze występowania licznych zagrożeń utożsamianych z epidemią COVID-19.
Moderne od reformacji do rewolucji. Polityka wyzwolenia, podmiotowość polityczna i porządek życia zbiorowego jako specyﬁczny problem
Authors: Kaczorowski Paweł
Published: April 2022

The article provides an overview and outline of key political and state problems in the early modern era in Western Europe. The new era shows politics in a new way as liberation politics and creates a new kind of political system – the state, which from then on is a permanent element of the culture of Europe in a broad sense. The state is also a kind of European ‘commodity’ exported all over the world. The article describes the close relationship between modern politics and the state as a product of occidental rationalism.
Study on deprotonation from radiation-induced ionized acrylate polymers including acid-generation promoters for improving chemically amplified resists
Authors: Okamoto Kazumasa , Konda Akihiro , Ishimaru Yuki , Kozawa Takahiro , Nakagawa Yasunobu , Nishimura Masamichi
Published: April 2022

The demand for improved performance of chemically amplified resists (CARs) is continually increasing with the development of extreme ultraviolet lithography. Acid-generation promoters (AGPs) increase the sensitivity of CARs by increasing the initial acid yield immediately after the exposure process. However, the detailed mechanism of acid-yield enhancement has not been clarified yet. Deprotonation from the ionized polymer (i.e. radical cations) is an important reaction to assess acid generation. In this study, we investigated the dynamics of the radical cations of methacrylate polymers and the effect of an AGP on deprotonation from the radical cations formed by ionizing radiation. We clarified that the promotion of deprotonation by the AGP is more effective for the polymer with lower deprotonation efficiency. In addition, a molecular-level approach using density functional theory and molecular dynamics calculations were carried out.
Wearable sensor device for posture monitoring and analysis during daily activities: A preliminary study
Authors: ÖZGÜL Gizem , PATLAR AKBULUT Fatma
Published: April 2022

The increase in technological advancements in recent years has led to the emergence of a new lifestyle. Although being assisted by machines for small-scale tasks in daily housework makes daily life easier, this has caused people to reduce their daily active movements and negatively affects human health. Especially during the COVID-19 pandemic, with the conversion of the working style to the home environment, working hours spent at the desk are more than ever. Due to the prolongation of the working time, the employees stay in the same position more inactive, thus their muscles weaken and they start to have muscle disease. Weaknesses in the muscles have occurred to the formation of postural problems in people. In our study, a smart vest system was developed to detect and control posture disorders. The proposed system is designed to recommend the most suitable exercises to avoid any physical discomforts. It is also aimed to detect hunched posture by collecting data on the person wearing the vest through sensors. Besides, it is encouraged to correct the posture disorder by warning the person audibly during the hunched posture. The experiments conducted with eight participants showed that the proposed system warns the users with necessary posture corrections, proving its potential use.
Peran Pendidikan Multikultural Dalam Meminimalisir Problematika Anak Di Sekolah
Authors: Suarlin Suarlin , Elpisah Elpisah , Mawaddati Noor Munadia
Published: April 2022

Pendidikan multikultural adalah usaha sadar untuk mengembangkan kepribadian didalam dan diluar sekolah yang mempelajari tentang berbagai macan status sosial, ras, suku, agama agar tercipta kepribadian yang cerdas dalam menghadapi masalah-masalah keberagaman budaya. Tujuan penelitian ini adalanh untuk mengetahui peran pendidikan multikultural dam meminimalisir problematika anak di sekolah.  Permasalahan yang sering terjadi memerlukan jalan keluar dan tindakan yang nyata. Oleh karena itu pendidikan multikultural memiliki peran dalam meminimalisir problematika anak disekolah seperti radikal atau perkelahian dan juga bullying. Metode penelitian ini dilakukan dengan menggunakan studi literatur, penelitian ini dapat diambil dari berbagai macam referensi yaitu dari jurnal ilmiah (online) dan internet. Hasil kesimpulan dari penelitian ini bahwa pendidikan multikultural yang dimasukkan ke dalam proses pembelajaran di sekolah akan memberikan peta pemahaman yang jelas kepada siswa-siswi di sek0lah ataupun madrasah dan hal ini tentunya akan mengurangi bahkan menghilangkan perilaku negatif dalam diri siswa seperti perilaku bullying yang mengarah kepada kekerasan secara fisik dan mental. Penelitian ini berkontribusi terhadap isu-isu pendidikan yang berupaya untuk memberikan karakter saling menghargai dalam diri siswa.
Image Restoration using Deep Learning Techniques
Authors:   B.Tech, Department of Computer Science, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad (Telangana), India., Aravinda Akurathi , Yoshitha Challagulla ,   B.Tech, Department of Computer Science, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad (Telangana), India., Meghana Kakarla ,   B.Tech, Department of Computer Science, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad (Telangana), India., Sreeja Kandula ,   B.Tech, Department of Computer Science, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad (Telangana), India., Tejaswi B. ,   Assistant Professor, Department of Computer Science, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad (Telangana), India.
Published: April 2022

In the modern era, due to the emergence of various technologies, most of the human work is now being performed by the computer system. The computer’s capacity to make everything possible is increasing as by the time. Photos are used to capture or freeze the moments in one’s life. We can embrace those moments at any time by looking at the pictures. It is natural that, as time passes by, these photos gets damaged due to environmental conditions that leads to loss of our important moments. Hence, preserving the photos is as important as taking them. The process of taking corrupt or noisy image and estimating the clean, original image is image restoration. Many forms of noise such as motion blur, camera misfocus etc., increases the complexity to restore the image. Image corruption comes in varying degrees of severity, the complexity of restoring photos in real-world applications will likewise vary greatly. Also, manual restoration is time consuming leading to lots of work to be piled up. To increase the capability of restoring old images from various defects, we must address several degradations intermingled in one old photo, such as structural defects like scratches and dust spots, and unstructured defects like sounds and blurriness. Furthermore, we may use a different face refinement network to restore small details of faces in ancient pictures, resulting in higher-quality photos. The aim of the work is to create a image restoration system that will be used to restore the images irrespective of the type of noise. In this paper, we present a model that would take image as an input and remove all the noises present in it to give a clean and restored image.