bluuebunny/crossref_metadata_2025 huggingface dataset:
Whether the Effect of Sperm DNA Fragmentation on the Clinical and Laboratory Outcomes Changes with the Paternal age in the intracytoplasmic sperm injection Cycles of Donor Oocytes
Authors: Repalle Deepthi , Kv Saritha , Bhandari Shilpa , Choudhary Jitendra
Published: August 2022

OBJECTIVE: The present study aimed to know the effect of paternal age together with Sperm DNA fragmentation on the clinical and laboratory outcomes in the donor oocyte intracytoplasmic sperm injection cycles.
STUDY DESIGN: In this prospective cohort study a total of 229 patients undergoing their first intracytoplasmic sperm injection cycles and fresh blastocyst embryo transfer with donor oocytes were included in this study. All the patients of the donor oocyte intracytoplasmic sperm injection cycles were categorized into four groups based on the male age and sperm DNA fragmentation. Ⅰ. Y group (Young, Male age <40 years) with low sperm DNA fragmentation (Sperm DNA fragmentation ≤30%), Ⅱ. Y group (Young, Male age <40 years) with high sperm DNA fragmentation, Ⅲ. Advanced paternal age group, Male age ≥40 years with low sperm DNA fragmentation (sperm DNA fragmentation≤30%), and Ⅳ. Advanced paternal age group, Male age ≥40 years) with high sperm DNA fragmentation (sperm DNA fragmentation>30%).
RESULTS: Clinical, as well as laboratory outcomes, were correlated among these four groups. There was no significant difference in the clinical outcomes among the groups, whereas coming to the laboratory outcomes, the advanced paternal age group with high sperm DNA fragmentation has significantly decreased good quality embryos (Grade A) at day 3 rate, blastocyst rate, and good quality blastocyst rate compared to other groups (p<0.05).
CONCLUSION: In conclusion, advancing paternal age together with high sperm DNA fragmentation has no deleterious effect on the clinical outcomes in the intracytoplasmic sperm injection cycles of donor oocytes.
How much water can bioretention retain, and where does it go?
Authors: Spraakman Sylvie , Martel Jean-Luc , Drake Jennifer
Published: August 2022

Bioretention is a type of green stormwater infrastructure for the urban environment that mimics a natural hydrologic system by reducing peak flows and runoff volumes and encouraging infiltration and evapotranspiration. This study examines the complete water balance of a bioretention system located in Vaughan, Ontario, Canada, between 2018 and 2019. The water balance was further broken down by event size, where the event size was determined by rainfall frequency analysis. Recharge was the largest component of the water balance overall (88% of inflow), as well as by event size. Evapotranspiration was the next largest water balance component (6% of inflow overall), and was a significant component of inflow (19%) when considering only small events (50% probability of recurrence). Evapotranspiration is a slow but consistent process, averaging 2.3 mm/day overall and 2.9 mm/day during the growing season. Climate change is likely to bring more wet days and higher temperatures, which will impact the bioretention water balance by increasing evapotranspiration and inflow. Design standards for retention targets should be updated based on the most recent rainfall frequency analyses to adjust for changing climate conditions.
Cultura tributaria y su relación con el cumplimiento de obligaciones tributarias - Mercado José Carlos Mariátegui - San Juan de Lurigancho
Authors: Seminario Unzueta Randall Jesús , Trinidad Montes Hilda Evelyne , Trinidad Montes Sheyla Veronika
Published: August 2022

Objetivo: Determinar la relación de cultura tributaria con el cumplimiento de obligación en tributarias en comerciantes del Mercado José Carlos Mariátegui – San Juan de Lurigancho. Materiales y métodos: El tipo de estudio fue no experimental, el diseño correlacional, aplicando dos cuestionarios confiables y debidamente validados a una población de 120 comerciantes del mercado José Carlos Mariátegui, distrito de San Juan de Lurigancho y se procesó la información a través del Software (SPSS v.26). Resultados: Presentados en tablas, determinan que la cultura tributaria se relaciona con la obligación tributaria con una rho=0,577, en cuanto a las dimensiones valores tributarios rho=0,586, educación tributaria rho=0,511, conciencia tributaria rho=0,466 y existe una correlación positiva media entre la conciencia tributaria y la obligación tributaria con coeficiente de correlación de Rho de Spearman de 0,466. Conclusiones: La cultura tributaria incide significativamente en el cumplimiento de obligaciones tributarias en los comerciantes del mercado José Carlos Mariátegui, observándose que existe una correlación positiva considerable.
Estrés laboral en enfermeros de areas criticas de un establecimiento hospitalario en Lima
Authors: Matta Solis Diana Karim , Matta Zamudio Lourdes Sukeyko
Published: August 2022

Objetivo: En este estudio se buscó determinar el estrés laboral durante la pandemia en enfermeros de áreas críticas de un establecimiento hospitalario en Lima. Materiales y métodos: La investigación tuvo como enfoque cuantitativo y su diseño metodológico fue descriptivo y transversal. La población estuvo compuesta por 52 enfermeros. La técnica empleada fue la encuesta y el instrumento aplicado fue el cuestionario NSS. Resultados: En cuanto al estrés laboral, predominaron aquellos con un nivel bajo con 53,8% (n=28) tienen un nivel bajo, seguido del nivel medio con 38,5% (n=20) tienen y nivel alto con 7,7% (n=4)  De acuerdo a sus dimensiones, en ambiente físico, predominaron aquellos con un nivel bajo con 71,2% (n=37), seguido del nivel medio con 23,1% (n=12) y nivel alto con 5,8% (n=4), en ambiente psicológico, predominaron aquellos con un nivel bajo con 50% (n=26), seguido del nivel medio con 42,3% (n=22) y nivel alto con 7,7% (n=4) y en ambiente social, predominaron aquellos con un nivel bajo con 63,5% (n=33), seguido del nivel medio con 28,8% (n=15) y nivel alto con 7,7% (n=4). Conclusiones: En cuanto al estrés laboral, predominaron aquellos con un nivel bajo, seguido del nivel medio y nivel alto. Según sus dimensiones, en ambiente físico, predominaron aquellos con un nivel bajo, seguido del nivel medio y nivel alto, en ambiente psicológico, predominaron aquellos con un nivel bajo, seguido del nivel medio y nivel alto y en ambiente social, predominaron aquellos con un nivel bajo, seguido del nivel medio y nivel alto.
Ansiedad por coronavirus en enfermeros que laboran en una Unidad de Cuidados Intensivos en Lima, 2021
Authors: Balladares Chavez Maria del Pilar
Published: August 2022

Objetivo: El estudio tuvo por objetivo, determinar la ansiedad por coronavirus en enfermeros que laboran en una Unidad de Cuidados Intensivos en Lima, 2021. Materiales y métodos: La presente investigación tuvo como enfoque cuantitativo y su diseño metodológico fue descriptivo y transversal. La población estuvo compuesta por 36 enfermeros que laboran en una unidad de cuidados intensivos. La técnica empleada fue la encuesta y el instrumento aplicado fue la escala ansiedad por coronavirus (CAS). Resultados: En cuanto a la edad de los participantes el mínimo fue 25 años, el máximo fue 53 años y la media fue 38,57 años. En cuanto al sexo, el 66,7% (n=24) son mujeres y el 33,3% (n=12) son varones. En cuanto a la ansiedad por coronavirus en enfermeros, predominaron aquellos con ansiedad disfuncional con 61,1% (n=22) y seguido de aquellos sin ansiedad disfuncional con 38,9% (n=14). Según sus ítems, en mareos, prevalecieron aquellos que tienen por más de 7 días con 44,4% (n=16), en trastorno del sueño predominaron aquellos que presentan varios días con 44,4% (n=16), en pérdida de apetito prevalecieron aquellos que tienen varios días con 47,2% (n=17) y finalmente en malestar abdominal prevalecieron aquellos que tienen varios días con 44,4% (n=16). Conclusiones: En cuanto a la ansiedad por coronavirus en el personal de enfermería, predominaron aquellos con ansiedad disfuncional y aquellos sin ansiedad disfuncional.
DOSIS Y MOMENTO DE APLICACIÓN DE CLORURO DE MEPIQUAT EN AJÍ ESCABECHE (Capsicum baccatum var. pendulum)
Authors: Nolasco Chumpitaz Juan , Casas Díaz Andrés
Published: August 2022

El objetivo del presente trabajo fue evaluar el efecto del cloruro de mepiquat aplicado a tres momentos y tres dosis distintas; en el desarrollo, rendimiento y calidad del cultivo de ají escabeche (Capsicum baccatum var. pendulum). En este experimento se utilizó un arreglo factorial de 23 en un diseño estadístico de bloques completos al azar (DBCA) con cuatro repeticiones, se realizó el análisis de varianza (ANVA) y prueba de comparación de medias de Duncan al 5% para los factores y niveles empleados. Las dosis y momentos evaluados fueron: cloruro de mepiquat a d1: 250; d2: 375 y d3: 500 ppm; momentos de aplicación a m1: 20, m2: 35 y m3: 50 días después del trasplante. No se hallaron diferencias estadísticamente significativas para la interacción del factor dosis x momento, tampoco para el factor momento. Se encontraron diferencias estadísticamente significativas para el factor dosis y sus niveles en las variables rendimiento y número de frutos por planta, obteniéndose el mayor valor en dichas variables a las dosis de 250 y 375 ppm de cloruro de mepiquat con un rendimiento de 21,16 – 21,07 t ha-1 y 23,24 – 22,94 frutos planta-1 respectivamente, independientemente del momento de aplicación. Por lo tanto, podemos decir que la aplicación de cloruro de mepiquat a dosis de 250 y 375 ppm tuvo un efecto positivo en el cultivo incrementando el rendimiento y numero de frutos por planta, sin considerar el momento de aplicación.
CALIBRACIÓN DE SENSORES DE REFLECTOMETRÍA DE DOMINIO TEMPORAL EN SUELOS ULTISOLES DE SABANA
Authors: Gil-Marín José , Cordova-Rodriguez María , Zermeño-Gonzalez Alejandro
Published: August 2022

El método de determinación del contenido de agua en el suelo a través de sondas TDR (Time Domain Reflectometry) estima el contenido de agua con base a la permisividad dieléctrica del suelo, utilizando un polinomio de tercer orden. Sin embargo, en algunas aplicaciones deben realizarse graduaciones in situ, que culminen en funciones individuales de calibración para cada tipo de suelo. Los objetivos de este estudio consistieron en realizar la calibración y determinar las ecuaciones específicas de un sensor de humedad CS616, en suelos Ultisoles de sabana de distintas texturas, colectados en diferentes zonas agrícolas del Municipio Maturín, estado Monagas, Venezuela. El estudio se llevó a cabo en recipientes cuadrados de acero inoxidable de 10 cm de lado y 32 cm de alto, implementados en condiciones controladas de un invernadero del postgrado de la Universidad de Oriente, donde se realizó el monitoreo diario de la humedad del suelo durante 30 días, desde la humedad de saturación hasta el secado natural. Los sensores CS616 presentaron una respuesta lineal a la variación de humedad de suelo obteniendo R2 >0,90. Los valores de RMSE antes y después de la calibración variaron de 0,119 a 0,012 m3m-3. Los índices de Willmott (d) y de rendimiento(c) indican que la ecuación de más ajuste se encontró en el suelo Franco arcilloso. Se concluye que las ecuaciones de calibración obtenidas fueron más precisas que las ecuaciones de fábrica en estos tipos de suelo.
THE AMAZING COLORS OF PERUVIAN BIODIVERSITY: SELECT PERUVIAN PLANTS FOR USE AS FOOD COLORANTS
Authors: Miyagusuku-Cruzado Gonzalo , Voss Danielle M. , Del Carpio-Jiménez Carla , Lao Fei , Jing Pu , Zhang Kai , Zhou Yucheng , Grouge Sydney , Giusti Monica M.
Published: August 2022

La creciente demanda de los consumidores de alimentos más nutritivos, ingredientes de origen natural y etiquetas más limpias está empujando a las industrias de alimentos y cosméticos a pasar del uso de colorantes artificiales a alternativas de origen natural. En este contexto, la industria busca continuamente fuentes de colorantes más estables, con especial interés en las fuentes vegetales. La vibrante biodiversidad que se encuentra en el Perú representa una emocionante oportunidad económica. En esta revisión, destacamos cultivos peruanos seleccionados con excelente potencial para su uso como fuentes de colorantes para aplicaciones industriales, con algunas fuentes que se estudian ampliamente y otras que reciben atención en años más recientes. El maíz morado, un cultivo nativo de la región de los Andes, es una rica fuente de pigmentos con gran estabilidad y una larga historia de uso en diferentes aplicaciones alrededor del mundo. Las papas de pulpa coloreada, cultivos andinos subutilizados, pueden expresar diferentes colores debido a sus perfiles de pigmentos variados. Sauco, la baya del saúco peruana, tiene una fuerte actividad antioxidante y un perfil de pigmento único que le da su característico color negro-púrpura. Las especies de Berberis, una clase diversa de arbustos con bayas altamente pigmentadas, se pueden usar directamente como aditivos de color sin necesidad de procedimientos de extracción. Huito, una fruta poco estudiada originaria del Amazonas es naturalmente incolora, pero puede volverse azul cuando se expone al oxígeno o a los aminoácidos y puede expresar diferentes tonalidades según la fuente del grupo de aminas primarias. En general, el maíz morado, las papas de pulpa coloreada, el sauco, las especies de Berberis y el huito son fuentes peruanas prometedoras de colorantes naturales para aplicaciones alimentarias y cosméticas debido a su versatilidad, estabilidad y atractivas características de color.
MEJORAS EN EL ACONDICIONAMIENTO TÉRMICO DE VIVIENDAS ALTOANDINAS EN LA REGIÓN PUNO
Authors: Linares Zaferson Víctor Eduardo , Cuéllar Cajahuaringa Nayeli
Published: August 2022

Durante los periodos de heladas en Puno, como en otras regiones altoandinas, la población más vulnerable, niños y ancianos, sufren problemas bronco-respiratorios y muerte por el inadecuado acondicionamiento térmico de sus viviendas. El objetivo de la investigación es evaluar el comportamiento térmico de un prototipo de vivienda “mejorada” construida en el distrito Santa Rosa (Puno) a 3800 m.s.n.m. y proponer alternativas para el mejoramiento del acondicionamiento térmico en la fabricación de módulos repetitivos. Para lo cual, se realizó el monitoreo de temperaturas interiores y exteriores de viviendas de manera continua en dos muestras durante días fríos con un intervalo de una hora utilizando equipos DataLogger, complementariamente se realizó un levantamiento físico de las viviendas. La evaluación de estos resultados determinó que las viviendas pierden calor por conducción de materiales de muros, techos, puertas y ventanas y a la inadecuada orientación de estas por asoleamiento y ventilación. Se plantearon alternativas de solución para el acondicionamiento térmico de la vivienda “mejorada” respecto a los problemas encontrados. Se observó que la mayor área de la envolvente compuesta por muros de adobe representa el 60% del total del cerramiento, y que, a pesar de ser un material de baja conductividad, representa el 77% de las pérdidas de calor por falta de un adecuado revoco. Considerando las modificaciones propuestas en la envolvente de la vivienda “mejorada” se ha logrado aumentar la temperatura interior en 1,87°C en las horas de más bajas temperaturas y mantener una temperatura promedio interior de 14°C.
Carbono almacenado en la biomasa aérea y su valoración económica en los sistemas agroforestales de la EEA San Bernardo, Madre de Dios - Perú
Authors: Clemente-Arenas Edith R.
Published: August 2022

Los sistemas agroforestales son una alternativa de manejo sostenible para las tierras degradadas por la agricultura convencional en la Amazonía peruana, esto podría evitar más deforestación de los bosques y la pérdida de más ecosistemas. El componente arbóreo en los sistemas agroforestales los hace más parecidos a los bosques naturales que muchos otros sistemas de uso de tierra como las pasturas, monocultivos, entre otros. Esta característica también repercute en el potencial de captura de carbono de los sistemas agroforestales ya que representan un considerable sumidero de carbono tanto sobre como debajo del suelo. En consecuencia, puede representar un considerable ingreso económico por parte de los bonos de carbono, el cual es un mecanismo internacional de descon­taminación para reducir las emisiones contaminantes al medio ambiente, con un mercado relati­vamente nuevo y con mucha relevancia en la mitigación del cambio climático. En ese sentido, se cuantificó y valorizo económicamente el carbono almacenado en la biomasa aérea de siete sistemas agroforestales establecidos hace más de 16 años en la Estación Experimental Agraria (EEA) San Bernardo. El diámetro de las especies frutales y forestales fue usado como insumo para las ecua­ciones alométricas que nos permitió estimar la biomasa y el carbono almacenado en el componente arbóreo de los sistemas agroforestales. Los siete sistemas agroforestales de la EEA San Bernardo tienen un total de 483.81 Mg de carbono almacenado en su biomasa aérea. Esta cantidad de carbo­no representa US$ 13,353.16 en bonos de carbono para el precio del 2020. La castaña (Bertholletia excelsa Bonpl.) fue la especie con mayor cantidad de carbono almacenado entre los siete sistemas agroforestales, mientras que el pashaco (Schizolobium amazonicum Huber ex Ducke) mostró una considerable cantidad de carbono almacenado a pesar de tener solo cinco años de haber sido plan­tado. Nuestros resultados demuestran que algunas combinaciones de especies forestales y frutales generan una competencia interespecífica que favorece al SAF haciéndolo más productivo en térmi­nos de crecimiento y de almacenamiento de carbono.
Diseño de un Sistema de Gestión de la Calidad para la Papelera Don Bosco, Nuevo Chimbote, Áncash - Perú
Authors: Díaz-Batalla Melina , Talavera-Ponce Úrsula , Gonzáles-Mora Héctor E. , Rojas-Arias Erik P.
Published: August 2022

El presente es un trabajo de investigación no experimental que se desarrolló en la Papelera Don Bosco, empresa dedicada a la elaboración de productos de papel artesanal con fibra de algodón que busca posicionarse en el mercado nacional y extranjero con un producto de alta calidad. Es así que, con el fin de mejorar en competitividad y asegurar la calidad de sus productos, se planteó como ob­jetivo diseñar un Sistema de Gestión de Calidad (SGC) en base a la norma ISO 9001:2008. Para ello, como punto de partida, se elaboró un análisis estratégico para determinar la misión, visión, valores y un análisis FODA. Así mismo, se realizó un diagnóstico de la empresa según los requisitos exigi­dos por la ISO 9001:2008, mediante una lista de verificación, así como también se aplicó la encuesta de Costos de Calidad del Instituto Mexicano de Control de Calidad (IMECCA). Los resultados del diagnóstico arrojaron que la asociación requería mejoras desde la organización de soporte hasta el aseguramiento de sus procedimientos. Según los estándares de la ISO 9001:2008, el SGC hallado fue deficiente, con un 44.58% de cumplimiento de la norma. Por su parte, la encuesta IMECCA, indicó que en la Papelera Don Bosco el 11.8% de sus ventas representan costos de calidad, específicamente en la evaluación y corrección de defectos. En función a estos resultados se procedió a diseñar el SGC para la Papelera Don Bosco. Para ello se propuso reorganizar la empresa en seis áreas, siete responsables, un Comité de la Dirección para la gestión de la Papelera y un Director para decisiones que involucren gastos importantes. Finalmente, se estimó el presupuesto de inversión para la imple­mentación del SGC en S/.18616.13.
The Needs of Medical Professionals in Performing their Duties during the COVID-19 Pandemic: A Qualitative Research Study
Authors: Phanphairoj Kanjanee , Muijeen Kasorn , Chumwichan Sutthisan
Published: August 2022

Introduction:

The COVID-19 pandemic situation is a huge global medical and public health issue that has affected people’s physical health and mental well-being. Under the current circumstances, medical professionals are at risk of stress, anxiety, and subsequent mental health problems.

Methods:

The present study aimed to explore the needs of medical professionals in terms of promoting their mental health while performing their duties during the COVID-19 pandemic. The purposive sampling method was used to select 43 medical professionals in the following five groups: physicians, dentists, pharmacists, nurses, and medical technicians, who were frontline health workers or had the risk of contracting infection from infected patients in Thai hospitals during the COVID-19 pandemic. The data were collected using a semi-structured online interview. The informants were asked to talk about the need for mental health promotion of medical professionals while performing their duties during the COVID-19 pandemic for approximately 60 minutes. Content analysis and a reliability test were conducted according to the qualitative research process.

Results:

The research results consisted of three main themes: 1) physical safety welfare, composed of COVID-19 prevention and COVID-19 treatment; 2) sources of mental support, comprising emotional support and electronic or media support; and 3) support from central professional agencies, including rewards and recognition and occupational protection.

Conclusion:

The medical professionals in this study suggested that the mental health promotion during the COVID-19 pandemic should cover the physical, mental, and social dimensions. Thus, a mental healthcare approach for medical professionals should be developed by focusing on social support.
Implementation of marketing mix as educational service marketing strategy at Langlangbuana University
Authors: Pramiarsih Euis Eka , Yunaningsih Ani , Syarkani Yofy
Published: August 2022

This study aims to describe the application of the marketing mix which is a service marketing strategy at Langlangbuana University, Bandung. The method used in this study is a qualitative method with a descriptive analysis approach based on the stages of planning, and implementing marketing strategies for educational services at Langlangbuana University, Bandung. The results of this study reveal that the marketing mix strategy which includes product, price, location, promotion of human resources, physical evidence, and processes in marketing education services, can be applied at Langlangbuana University.
Evaluating a Global Assessment Measure Created by Standardized Patients for the Multiple Mini Interview in Medical School Admissions: Mixed Methods Study
Authors: Kennedy Ann Blair , Riyad Cindy Nessim Youssef , Ellis Ryan , Fleming Perry R , Gainey Mallorie , Templeton Kara , Nourse Anna , Hardaway Virginia , Brown April , Evans Pam , Natafgi Nabil
Published: August 2022

Background

Standardized patients (SPs) are essential stakeholders in the multiple mini interviews (MMIs) that are increasingly used to assess medical school applicants’ interpersonal skills. However, there is little evidence for their inclusion in the development of instruments.

Objective

This study aimed to describe the process and evaluate the impact of having SPs co-design and cocreate a global measurement question that assesses medical school applicants’ readiness for medical school and acceptance status.

Methods

This study used an exploratory, sequential, and mixed methods study design. First, we evaluated the initial MMI program and determined the next quality improvement steps. Second, we held a collaborative workshop with SPs to codevelop the assessment question and response options. Third, we evaluated the created question and the additional MMI rubric items through statistical tests based on 1084 applicants’ data from 3 cohorts of applicants starting in the 2018-2019 academic year. The internal reliability of the MMI was measured using a Cronbach α test, and its prediction of admission status was tested using a forward stepwise binary logistic regression.

Results

Program evaluation indicated the need for an additional quantitative question to assess applicant readiness for medical school. In total, 3 simulation specialists, 2 researchers, and 21 SPs participated in a workshop leading to a final global assessment question and responses. The Cronbach α’s were >0.8 overall and in each cohort year. The final stepwise logistic model for all cohorts combined was statistically significant (P<.001), explained 9.2% (R2) of the variance in acceptance status, and correctly classified 65.5% (637/972) of cases. The final model consisted of 3 variables: empathy, rank of readiness, and opening the encounter.

Conclusions

The collaborative nature of this project between stakeholders, including nonacademics and researchers, was vital for the success of this project. The SP-created question had a significant impact on the final model predicting acceptance to medical school. This finding indicates that SPs bring a critical perspective that can improve the process of evaluating medical school applicants.
Predicting and Detection of drug side effects based on Graph Attention Network (Preprint)
Authors: Rajaei Fatemeh , moqadam charkari nasrollah
Published: August 2022

BACKGROUND

In the last decade, many studies have investigated on predicting the potential side effects of drugs. In general, this study could be divided into two categories; detection and prediction.
Detection aims to detect the side effects of existing drugs. In Prediction, the side effects of new drugs are studied. In general, when a new drug enters the drug discovery cycle, its side effects are unknown.

OBJECTIVE

Despite the positive effects of drugs for the prevention, diagnosis, and treatment of diseases, the side effects of some drugs could not be ignored. Many diseases and death are reported annually due to drug side effects. In general, predicting drug side effects using laboratory methods is very costly and time-consuming. On the other hand, these methods are not able to diagnose all the drug side effects due to many limitations.

METHODS

We attempt to obtain effective embedding for drugs and their probable side effects using the Graph attention network. Furthermore, drug side effects links are predicted using these embedding.

RESULTS

Using semantic and structural properties of drug network has properly increased the prediction and further detection of side effects. The results indicate Area Under Precision-Recall of 0.7258 and 0.7184 on this research dataset, respectively.

CONCLUSIONS

Using positive and negative examples in loss function and self-attention deployment in Graph attention network result in more reliable embedding and better accuracy results in prediction. Moreover, the significant effect of embedding in predicting links has been shown in this study.
Arsitektur Indis dan Perubahan Sejarah Kota Magelang 1906-1942
Authors: Adyt Alkautsar  , La Ode Rabani
Published: August 2022

This study discusses the architecture of Indische buildings at Magelang Town in 1906-1942. This study uses historical research methods consisting of heuristics, source verification, data interpretation and historiography. The entry and development of Indische architecture in Magelang Town coincided with the increasingly intensive colonial government in exploiting natural resources in order to increase commodity exports. This building with Indische architecture in Magelang Town developed from 1906 to 1942 along with the fulfillment of the facilities and needs of the Dutch people who were intensively running the bureaucracy in Magelang Town. The facilities and needs referred to are infrastructure, especially housing, offices, and defense as illustrated in residential buildings, schools, lodging, hospitals, and other public facilities. In 1942, Indische architecture no longer developed in line with the end of Dutch rule in the Dutch East Indies. However, some of the Indische buildings in Magelang Town are still maintained by the community.
AI provides congruent and prescriptive feedback for squat form: qualitative assessment of coaching provided by AI and physical therapist
Authors: Luna Alessandro , Denham Michael W
Published: August 2022

Objectives:
To assess style and themes of feedback provided by artificial intelligence (AI) mobile application and physical therapist (PT) to participants during bodyweight squat exercise.
Methods:
Research population was age 20–35, without any pre-existing condition that precluded participation in bodyweight exercise. Qualitative methodology followed directed content analysis. Cohen's kappa coefficient verified consistency between coders.
Results:
Both AI and PT groups had seven female and eight male participants. Three themes emerged: affirmation schema, correction paradigms and physical assessments. Average kappa coefficient calculated for all codes was 0.96, a value that indicates almost perfect agreement.
Conclusion:
Themes generated highlight the AI focus on congruent, descriptive and prescriptive feedback, while the PT demonstrated multipoint improvement capabilities. Further research should establish feedback comparisons with multiple PTs and correlate qualitative data with additional quantitative data on performance outcomes based on feedback.
Servicios tecnológicos de laboratorio para el sector agropecuario Colombiano: un análisis científico de los paisajes
Authors: Santacruz-Castro Adriana Marcela , Moreno-Rodríguez Jenny Milena , Santana-Medina Jairo Javier , Florez-Martínez Diego Hernando
Published: August 2022

El propósito de este artículo es analizar la forma en que los servicios tecnológicos desarrollados en un centro de investigación para el sector agropecuario han contribuido a la mejora de procesos de I+D+i y se alinean con las tendencias mundiales en tecnologías para el cambio técnico. Lo anterior, como insumo para orientar el fortalecimiento de capacidades y dinamizar la oferta de servicios en favor de la competitividad del sector. La metodología de este análisis contempló el uso de herramientas de inteligencia competitiva y vigilancia tecnológica, enfocadas al análisis de publicaciones científicas asociadas a los servicios tecnológicos ofertados. Esta metodología abarcó un diseño secuencial de tres fases, que tuvieron como resultado el estado actual de contribución de los servicios tecnológicos de laboratorio a la generación de conocimiento científico en ocho ejes de trabajo. A partir de este análisis se generó una propuesta de hoja de ruta para el fortalecimiento y alineación de los servicios tecnológicos de laboratorio del centro de investigación, frente a las tendencias en el contexto mundial.
The Diagnostic Utility of Interleukin-13 and Interleukin-17A using the ELISA Technique in Asthmatic Children
Authors: AL-Hasnawi Sawsan M. Jabbar , Al-khayat Dhiaa H. Jawad
Published: August 2022

The heterogeneous etiology of asthma makes its diagnosis complicated. Measurement of cytokine levels could be relevant in determining the asthma phenotype, predicting severity, and identifying the treatment type. Enzyme-linked immunosorbent assay (ELISA) is one of the most reliable methods, with high sensitivity and specificity. This study aimed to determine the accuracy and utility of interleukin (IL)-13 and IL-17 A in diagnosing children with asthma. A total of 74 asthmatic and 75 healthy children were enrolled in this case-control study between 10/2019 and 3/2021. Sera were collected and analyzed for IL-13 and IL-17A using ELISA. Diagnostic utility assessment was performed using receiver operating characteristic (ROC) analysis. The results showed that both cytokines had a significant capacity to differentiate patients with asthma from the control group. The sensitivity and specificity for IL-17A were 97.3% and 52.0%, respectively, whereas for IL-13 it was 81.1% and 52.0%, respectively. Positive predictive values (PPV) were 66.7% and 62.5% for IL-17A and IL-13, respectively. In conclusion, although both biomarkers had low specificity, IL-17A was more sensitive in differentiating children with asthma from those in the control group and had a higher sensitivity rate than IL-13.
Fatty Acids and Elements Profile of Different Parts from Congress grass (Parthenium hysterophorus L.)
Authors: Begum Ghazala , Dastagir Ghulam , Rauf Abdur , Bawazeer Sami , Naz Saima , Semwal Prabhakar , Khan Imtiaz Ali , Al-Awthan Yahya S. , Bahattab Omar , Al-Duais Mohammed A. , Ramadan Mohamed Fawzy
Published: August 2022

Congress grass (Parthenium hysterophorus L., family Asteraceae) is found generally in agricultural and vacant lands across the globe. This study investigated the fatty acids and elemental profiles of different parts including roots, stem and leaves of P. hysterophorus in the response to seasonal variation. The elemental analysis and fatty acid were determined in both the winter and summer seasons. The root, stem, and leaves powder were subjected to extraction with acetone, water, chloroform, diethyl ether, ethanol, methanol, and n-hexane to measure the extractive values. Among all the plant parts, leaves recorded the highest extractive value of 29%, and 28% with acetone and diethyl ether, respectively, while the root recorded the lowest (10.3%) extractive value with chloroform. Higher concentrations of saturated and unsaturated fatty acids were detected in all the plant parts in the winter collection than in the summer season. Parthenium hysterophorus is multi medicinal applications such as used for rheumatic pain, urinary tract infections, inflammation, diarrhea, neuralgia, and malaria. The study highlights the importance of collection time (seasons) of different parts of P. hysterophorus for the maximum extraction of both elements and fatty acids either saturated or unsaturated from the pharmacogenetic point of view.
Community-acquired Methicillin-resistant Staphylococcus aureus Pneumonia and Parapneumonic Effusion in a Male Patient with Diabetes: A Case Report
Authors: Sathyakamala R. , Shanmugam Priyadarshini , Meenakshi N.
Published: August 2022

Methicillin-resistant Staphylococcus aureus (MRSA) infections are a primary health concern. They are commonly differentiated as hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) and community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections, based on their epidemiology, susceptibility findings, and molecular typing patterns. Therefore, appropriate contact precautions and isolation measures should be implemented. CA-MRSA mostly causes skin and soft-tissue infections, but the probability and incidence of it causing sepsis and invasive infections have increased dramatically in recent years. In this study, we report a case of CA-MRSA pneumonia with pan-pneumonic effusion in a 59-year-old male diabetic patient with preexisting comorbidities such as diabetic ketoacidosis and non-ST elevated myocardial infarction. The early reporting of the organism’s identity and its antimicrobial susceptibility, as well as timely initiation of antibiotic therapy, aided in the successful management and cure of the patient.
Evaluating the Diagnostic Accuracy of Rapid Immuno-chromatographic Tests for Early Detection of Rotavirus in Fecal Samples from Children Less than Five Years with Acute Watery Diarrhea
Authors: Pawar Manaji , Karande Geeta
Published: August 2022

Acute diarrheal illness is a serious public health issue in developing and developed economies, with high morbidity and mortality rates. Children below five years are the most vulnerable, with one in every six dying from diarrhea. Diarrhea may be caused by various viruses, protozoa, and bacteria. Rotavirus, in particular, is often associated with diarrhea in children. Early detection of rotavirus infection reduces the need for medication and the spread of the virus and helps determine the optimal treatment strategies. In this study, we compared the efficacy of the rapid immunochromatography technique (ICT) with that of enzyme-linked immunosorbent assay (ELISA) to detect rotavirus antigens in stool samples. Overall, 361 stool samples were obtained from hospitalized children under five-years-old, with acute watery diarrhea symptoms and were tested by both rapid ICT and ELISA. Among these samples, 104 (28.81%) tested positive by ICT and 109 (30.19%) by ELISA. Furthermore, the specificity and sensitivity of ICT were assessed using ELISA, the gold standard test. ICT had a 95.41% sensitivity and a 100% specificity. Thus, during emergency testing, ICT may be utilized as an alternative test for quick diagnosis with high specificity and sensitivity in patients with rotavirus diarrhea.
Machine Learning Techniques to Thyroid Diagnosis and Treatment Prediction
Authors: B N Chandrika , D Sindhu , G K Dr. Ravikumar
Published: August 2022

Abstract: The thyroid is a steroid hormone that is located in the front of the neck. Its main function is to produce the thyroid gland, that is necessary for our overall health. This is a probable failure can result in thyroid hormone production that is either insufficient or excessive. As a result of one or maybe more swellings growing inside the thyroid, it might become inflamed or enlarged. Some of these nodules may harbor cancerous tumors. Sodium levothyroxine, generally defined as LT4, is a synthesized thyroid hormone used to treat thyroid problems and diseases and is one of the most commonly used medications. Predictions about therapy can help endocrinologists do their jobs better and enhance the quality of life for their patients. Numerous research has been published to date which focuses on the prognosis of thyroid illnesses based on the development of people's hormonal markers. This study, on the other hand, tries to forecast the LT4 therapy trend for hypothyroidism patients. A specific dataset containing clinical records on patients treated at Naples' "AOU Federico II" hospital was created to achieve this purpose. Because each patient's whole medical history can be accessed at any moment, it was possible to forecast the duration of each patient's therapy based on the trend of hormonal attributes and other features analyze, in order to determine whether it should be raised or decreased. We used a variety of machine learning methods to conduct this research. In specifically, we looked at the results of ten classification techniques. The findings of the various methods are promising, specifically in the context of the Additional Classifier, which achieves an accuracy of 84 percent.
The Effect of Government Regulations on Overall Economic Well Being in India (1995-2020)
Authors: Das Aditi , Mohan Muskan , Sultania Nitya , Yadav Ishika
Published: August 2022

Abstract: Barriers to trade and other market regulations have long been thought to inhibit the ability of aNation’s economy to grow and prosper. We test this hypothesis using a multiple regression model and data from The Heritage Foundation and World Bank related to trade freedom and general economic regulation on a country to fully discern the impact of governmental regulation on a country’s GDP per capita. We find that GDP per capita rises significantly as a India’s business freedom and trade freedom grow. This provides strong confirmation for our hypothesis that deregulated economies experience higher levels of economic prosperity as measured by GDP per capita than their regulated counterparts and indicates that a market-specific look shouldbe taken to fully understand the nuances of the results of different types of economic regulation.
Comparison of Pinned Support and Fixed Support Pre-Engineering Aircraft Hangar
Authors: Kumar Ashutosh , Yadav Prince
Published: August 2022

Abstract: Conventional steel buildings are an old concept that requires a significant amount of time and money. To modify A pre-engineering concept is being developed for this problem. It introduced to the Indian market in 1990’s.PEB concept is totally versatile due to its quality, prefabrication, light weight and economical construction. In structural engineering, a pre-engineered building (PEB) is designed by a manufacturer to be fabricated using a pre-determined inventory of raw materials and manufacturing methods that can efficiently satisfy a wide range of structural and aesthetic design requirements. Pre engineered steel buildings can be fitted with different structural accessories including mezzanine floors, canopies, fascias, interior partitions etc. and the building is made water proof by use of special mastic beads, filler strips and trims. A hangar is a closed structure to hold aircraft or spacecraft in protective storage. Hangars are used for protection from weather, protection from direct sunlight, maintenance, repair, manufacture, assembly and storage of aircraft on airfields, aircraft carriers and ships. In this study, a 60m clear span aircraft hangar is developed using STAAD Pro and compared to a C- Section and H- section PEB.
A Numerical Study on Fluid Flow and Heat Transfer in a Flow Interrupting Ribbed Microchannel under Inlet Flow Pulsation
Authors: Nandi Tapas Kumar , Duari Santanu
Published: August 2022

Abstract: The present work investigates the effect of pulsation on the transport process in a 2D microchannel. The inlet velocity varies sinusoidally in time at a constant dimension less frequency (St=10) and amplitude of 0.8. The working fluid is considered as water which is made to flow in the flow disturbing microchannel whiles the microchannel walls were kept at a uniform temperature. The solution of two-dimensional Navier-Stokes equation was performed using the SIMPLE algorithm with the momentum interpolation technique. The simulations were performed in the laminar regime within the Reynolds number range between 100- 500 for the microchannel. The results of pulsating flow simulations had been analysed and compared with nonpulsating flow simulations. It is observed that the effect of pulsation in flow interrupting ribbed microchannel is significant and more enhancement of heat transfer is observed at higher Reynolds number while keeping the friction factor within tolerable limits
Implementation of PLC Based Automated CNG Tank for Chuter Assembly Line
Authors: Patil Prof. S. J. , Appannavar Aditya
Published: August 2022

Abstract: The purpose of this study is to discuss Programmable Logic Controller (PLC). PLC is a type of digital computer that automates electromechanical activities like controlling machinery or manufacturing lines, among others. PLC’s are employed in numerous equipment and industries. The primary purpose of implementing a PLC is to eliminate concerns with relay irregularity and logic control. HMI (Human Machine Interface) is used in conjunction with a PLC to control and monitor the performance of industrial devices The aim of this project is to illustrate the usage of PLC in automated CNG tank for chuter assembly line and the utilization of its high capabilities and efficiency to process input and output signals from several sensors. With the help of software validation and hardware implementation used for demonstrating the ease of operation with the control system.
The Effectiveness of Add-on Treatment with Nutraceutical
Authors: Ivashkin V. T. , Morozova M. A. , Poluektova E. A. , Shifrin O. S. , Beniashvili A. G. , Rupchev G. E. , Alekseev A. A. , Poluektov Yu. M. , Mamieva Z. A. , Kovaleva A. L. , Ulyanin A. I. , Trush E. A.
Published: August 2022

Aim:evaluation of the effectiveness of the nutraceutical “Standard Zdorovia: Gastro” (“SZ Gastro”) in the treatment of patients with irritable bowel syndrome (IBS).

Materials and methods.52 patients (62 % women) diagnosed with IBS and IBS in combination with functional dyspepsia (FD) were included in the study and divided into two groups. Both groups received basic therapy according to the guidelines. The experimental group received as add-on the nutraceutical “SZ Gastro” (containing a standardized amount of menthol, gingerol and D-limonene); patients in the control group — placebo. The duration of the study was 30 days. The severity of somatic symptoms was assessed with the 7×7 questionnaire. Emotional state was assessed with the Four Dimensional Distress, Depression, Anxiety, and Somatization Questionnaire (4DSQ).

Results.Patients of the experimental and control groups did not differ from each other either in terms of demographics, basic treatment, or in the severity of symptoms at the beginning of the study.

The effectiveness of the treatment in the patients, who received add-on “SZ Gastro” was significantly higher than in the patients of the control group: in the control group the percentage of improvement of somatic symptoms was 22.35 %, in the experimental group it amounted to 49.18 % (χ2= 15.9;p= 0.0001). The percentage of patients with significant decrease of emotional disturbances was also higher in the experimental group: distress (χ2= 18.7;p= 0.0000), anxiety (χ2= 6.9;p= 0.0097) and somatization (χ2= 14.99;p= 0.0001). No significant side effects were registered in any of the groups.

Conclusions.Add-on of nutraceutical “SZ Gastro” to basic treatment is safe and significantly increases effectiveness of the therapy in the patients with IBS and IBS in combination with PD.
Modern Approaches in the Morphological Diagnosis of Inflammatory Bowel Diseases
Authors: Tertychnyy A. S. , Akhriyeva Kh. M. , Kogan E. A. , Zayratyants O. V. , Selivanova L. S.
Published: August 2022

The purpose of the review:to summarize the main data of the literature and our own accumulated practical experience of everyday diagnosis of inflammatory bowel diseases (IBD) to better represent the morphological features and histological conclusions.

Key points.The microscopic picture of IBD is often represented by a combination of basic histological characteristics that can be detected in other diseases and only in rare cases can be considered pathognomonic. No single histological feature can be used in isolation to diagnose ulcerative colitis or Crohn’s disease. Diagnostic accuracy is improved if several signs are taken into account at once, if changes within one or more parts of the intestine are analyzed, it is necessary to compare the identified changes with the clinical picture of the disease.

Conclusion.The presented stages of the morphological study of biopsy specimens in patients with IBD and the exact characteristics of the detected changes will help to increase the diagnostic value of the study of ileo- and colonobiopsies, as well as improve mutual understanding between gastroenterologists and pathologists and, as a result of interaction between specialists, will increase the accuracy of the diagnosis.
COVID-19 Pandemic and Irritable Bowel Syndrome — is there a Relationship?
Authors: Akhmedov V. A.
Published: August 2022

The aim: to reflect the features of the course of irritable bowel syndrome during the COVID-19 pandemic.

Key points. It has been noted that the COVID-19 may contribute to the formation of post-infectious functional gastrointestinal diseases, given that angiotensin-converting enzyme-2 (ACE-2) receptors, the site of binding of the SARS-CoV-2 virus to human cells, are also present in epithelial intestinal cells; virus was found in feces in about half of patients, gastrointestinal symptoms, including diarrhea occur in about one fifth of patients, fecal calprotectin, a marker of GI inflammation is elevated in patients with COVID-19, macroscopically as well as histologically, patients show signs of damage mucous membrane of the gastrointestinal tract, and also, as noted above, they have a dysbiosis of the intestinal microbiota.

Conclusion. It was shown that during the pandemic, more than 90 % of the interviewed patients with IBS had an exacerbation of IBS with an increase in symptoms such as bloating and cramps, and 75 % of them said that the exacerbation of symptoms was reflected in the activity of patients in everyday life. These factors dictate the need for an integrated approach in the management of such a group of patients with the use of modern multi-target drugs that affect the pathogenetic factors in the formation of functional gastrointestinal diseases, one of which is the Kolofort drug due to the triple multi-target mechanism of action on the pathogenesis of functional gastrointestinal diseases.