bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between the composite dietary antioxidant index and constipation: evidence from NHANES 2005-2010
Authors: Wei Shouxin , Yu Sijia , Lan Yunsheng , Jia Yingdong
Published: August 2024

Background
Dietary antioxidants have been found to improve various diseases, including digestive, cardiovascular, and urinary disorders. However, the relationship between the composite dietary antioxidant index (CDAI) and constipation remains unclear. This study aims to investigate the potential link between CDAI and constipation among adults in the United States.
Methods
This study utilized data from the National Health and Nutrition Examination Survey (NHANES) collected between 2005 and 2010. Dietary data from the respondents were obtained through two 24-hour dietary recall interviews. Multiple statistical methods, including multivariable logistic regression, subgroup analysis, and smooth curve fitting analysis, were used to explore the association between CDAI and chronic constipation.
Results
A total of 10,904 participants were included in the study, of whom 1,184 were identified as having chronic constipation. After adjusting for potential confounders, multivariable logistic regression analysis showed that higher CDAI was significantly associated with a lower risk of constipation (OR = 0.958 [0.929, 0.987]). Compared to the lowest quartile, the highest quartile of CDAI was associated with a significantly reduced prevalence of constipation (OR = 0.704 [0.535, 0.927]). Subgroup analysis indicated that differences in gender, alcohol intake, and smoking status might influence the association between CDAI and constipation. Smooth curve analysis revealed an "n" shaped relationship between CDAI and constipation among non-alcohol consumers, with a turning point at a CDAI value of 1.08.
Conclusion
An elevated CDAI is negatively correlated with the incidence of chronic constipation, suggesting that increasing dietary antioxidant intake may reduce constipation prevalence. These findings underscore the importance of dietary antioxidants in maintaining gut health and provide comprehensive guidance for clinical and public health practices.
Relevance Of The uMap Collaborative Platform As A Support For Choropleth Mapping: An Atlas Applied To All-Cause Excess Mortality Alerts By Traffic Light - 1st French Containment In 2020
Authors: QUESNEL-BARBET Anne , PAGES Thierry , SOULA Julien , MAIGNANT Gilles , HANSSKE Arnaud
Published: August 2024

In the wake of the health crisis, for the year 2020 we have created a France-wide geomatic project to produce several atlases of mortality for all pathologies, with very fine grids at commune and arrondissement levels (Marseille, Lyon, and Paris).
The aim is to bring to the collaborative map-sharing platform uMap environment, original visualization and knowledge, and decision-making aids, complementary to existing information and relevant to both the general public and healthcare professionals.
Method: We followed a two-step geomatic action plan (with and without webmapping) to create, from each of our four variables, an atlas of the 1st French containment period. Interpretation of the atlas is facilitated by the graphical display of colored choropleth maps with legend and statistical tooltip, and by rapid transmission to the user of an "Excess Mortality alert". In two different webmapping environments tested in advance, our
results only display uMap and its TrafficLight atlas, that instantly transmits the Excess Mortality alert by means of semantic interplay of colors. Comparison between regions is facilitated by the display of administrative contours and by a layer and legend management tool. Today, uMap delivers the expected results without having to worry about its remote server managed by OpenStreetMap, and its interoperability allows atlases to be exported and printed.
Outlook: Having taken a step back from geomatic technologies, uMap shows great potential for its implementation dedicated to healthcare on a local server. Further development, to create and associate legends with choropleth maps, could increase uMap’s functionality and interest.
Conclusions: We have innovated, demonstrated and reinforced the value of the collaborative and interoperable uMap mapping platform for visual rendering by instantiating our thematic atlases with choropleth maps and their legends. The TrafficLight atlas is highly relevant for the instant message it communicates by commune, and in this way, we have provided additional information easy to interpretable for all audiences. Finally, uMap offers many advantages in terms of licensing, design, and use of the atlases. This encourages us to continue improving it with the help of its contributors, and to explore it further, with an optimized geomatic action plan.
Spatiotemporal computations in the insect celestial compass
Authors: Gkanias Evripidis , Webb Barbara
Published: August 2024

To obtain a geocentric directional reference from a celestial compass requires compensation for the sun’s movement during the day, which also depends on the time of year and the observer’s latitude. We examine how insects could solve this problem, assuming they have clock neurons that represent time as a sinusoidal oscillation, and taking into account the known neuroanatomy of their celestial compass pathway. We show how this circuit could exploit trigonometric identities to perform the required spatiotemporal calculations. Our basic model assumes a constant change in sun azimuth (the 'hour angle'), which is recentred on solar noon for changing day lengths. In a more complete model, the time of year is represented by an oscillation with an annual period, and the latitude is estimated from the inclination of the geomagnetic field. We evaluate these models in simulated migration and foraging behaviours and discuss their potential for practical applications in robotics.
Differentiation between mpox infection and MVA immunization by a novel machine learning-supported serological multiplex assay
Authors: Stern Daniel , Surtees Rebecca , Treindl Fridolin , Akhmedova Shakhnaz , Beslic Denis , Bayram Fatimanur , Sesver Akin , Thi My Linh Nguyen , Rinner Thomas , Grossegesse Marica , Skiba Martin , Michel Janine , Körber Nils , Jansen Klaus , Koppe Uwe , Ulrich Marcus , Friedrich Nicole , Mankertz Annette , Ladewig Katharina , Mages Hans Werner , Dorner Brigitte , Nitsche Andreas
Published: August 2024

With case numbers exceeding 97,000 worldwide, the 2022 global mpox outbreak underscored the potential for zoonotic diseases with limited human-to-human transmission to trigger a widespread health crisis. Primarily men who have sex with men (MSM) were affected. Monitoring mpox-specific seroprevalences through epidemiological studies is essential, but challenging due to the cross-reactive antibody immune response which is induced by several orthopoxviruses including modified vaccinia virus Ankara (MVA)-based vaccines, which were used to help bring the outbreak under control. Here we show how machine learning (ML)-guided analysis of a serological multiplex assay that targets 15 immunogenic poxvirus proteins derived from monkeypox virus, vaccinia, and cowpox virus, can confidently discern between sera from patients post-mpox infection, post-MVA immunization, and pre-immunization or infection. Mean F1 scores representing the geometric means between precision and recall were calculated as metrics for the performance of six different ML models. The models were trained and tested on panels containing both sera taken in the early phase of seroconversion as well as sera taken six months after the peak of the mpox outbreak from individuals in an at-risk MSM population in Berlin. Scores ranged between 0.60 ± 0.05 and 0.81 ± 0.02 with Gradient Boosting Classifier (GBC) being the best performing algorithm. In order to ensure high confidence in our results, which is imperative in epidemiological studies, we excluded ambiguous results by using the robustly performing linear discriminant analysis’ (mean F1 scores 0.80 ± 0.02) classification confidence as a threshold. Hereby, sera with uncertain serostatus were segregated, leading to confident predictions with F1 scores above 0.90, at the cost of more inconclusive results for samples below the threshold. Beyond providing a valuable tool for monitoring mpox-specific antibodies, our work demonstrates how the combination of machine learning and multiplexing enables precise differentiation — and a deepened understanding — of complex antibody responses to closely related viruses.
Evaluation of Splanchnic Blood Flow Using Doppler Ultrasound Before and After Constipation Treatment in Patients with Bladder and Bowel Dysfunction
Authors: Gulcin Neslihan , Bozbeyoglu Sabriye Gulcin , Canmemis Arzu
Published: August 2024

Purpose: To evaluate the correlation between blood flow dynamics using conventional and Doppler ultrasound (US), and to assess the rectosigmoid ratio ultrasonographically in children with suspected bladder and bowel dysfunction (BBD).
Methods: This prospective study was conducted between January 2023 and January 2024 involving 62 children aged 5–18 years. Ultrasound were used to measure peak systolic velocity (PSV), pulsatility index (PI), resistive index (RI) of arteries, and the rectosigmoid ratio (R/S). Behavioral therapy and osmotic laxative treatment were administered for 3 months, followed by reassessment.
Results: Before treatment, the study group had a mean rectal diameter of 18 ± 15.5 mm, which increased to 23.5 ± 14.25 mm post-treatment (p = 0.008). The mean sigmoid colon diameter was 18.5 ± 10 mm before treatment and 18 ± 5 mm after treatment (p = 0.004). The rectosigmoid ratio (R/S) increased from 0.97 ± 0.76 to 1.27 ± 0.65 post-treatment (p = 0.036). No significant differences were found in the aortic, CA, and SMA flow velocities, PI, and RI between the groups or pre- and post-treatment within the study group. However, patients with an R/S index ≥1 had lower celiac PSV values compared to those with an R/S index <1 (p = 0.009).
Conclusion: Doppler ultrasound evaluation of intestinal blood flow did not show significant clinical benefits, it may offer insights for future research. Noninvasive measurement of the rectosigmoid index is useful in diagnosing and planning treatment for constipation, especially in cases with diffuse motility problems rather than fecal impaction.
Comparison of local recurrence outcomes between breast conservation therapy versus mastectomy for treatment of breast cancer among young woman: A systematic review and meta-analysis
Authors: Ma Xiaowen , Sun Yiming , Guo Qi , Zhang Feng
Published: August 2024

Background: Recent clinical trials comparing local recurrence rates in young breast cancer(BC) patients after breast-conserving therapy (BCT) vs. mastectomy are scarce. This meta-analysis aims to determine the optimal surgical approach for this group by assessing local recurrence (LR) rates between BCT and mastectomy.
Methods: We systematically searched four electronic databases (Medline, PubMed, Cochrane Library, and Web of Science) for relevant studies comparing LR rates in BC patients ≤40 years old treated with BCT plus radiotherapy or mastectomy. Studies meeting the inclusion criteria were synthesized using a random-effects model, with a focus on LR rates. We conducted sensitivity analyses and meta-regression to assess publication bias and heterogeneity, ensuring a rigorous evaluation of the available evidence.
Results: Out of 485 screened citations, 11 studies encompassing 9215 patients were included, with 4190 undergoing BCT and 5025 undergoing mastectomy. The summary OR revealed a significantly higher risk of LR for BCT compared to mastectomy among young breast cancer patients (OR = 1.63; 95% CI: 1.25-2.13). Specifically, the BCT group exhibited a higher 5-year LR rate (OR = 1.86, 95% CI: 1.13-2.62) and a 5-10-year LR rate (OR = 1.50, 95% CI: 1.00-2.25) compared to the mastectomy group. This trend held true across tumor stages, with the BCT group showing increased LR risk for both T1-2 (OR = 1.88, 95% CI: 1.20-2.94) and T1-4 (OR = 1.46, 95% CI: 1.02-2.10) stages. Similarly, nodal status analysis indicated a higher LR risk for BCT in N0-1 (OR = 2.56, 95% CI: 1.90-3.44) and N0-3 (OR = 1.38, 95% CI: 0.99-1.93) stages. Notably, among very young women (age ≤ 35), the difference in LR rate between BCT and mastectomy was pronounced (OR = 2.04, 95% CI: 1.48-2.81). Overall, for breast cancer patients aged ≤ 40 years, the BCT group consistently demonstrated a higher risk of LR compared to the mastectomy group (OR = 1.53, 95% CI: 1.10-2.13).
Conclusion: Our meta-analysis revealed that among young breast cancer patients, BCT was associated with a significantly elevated risk of LR compared to mastectomy, particularly in those ≤35 years old. This heightened risk persisted across various tumor and nodal stages. For very young breast cancer patients, a comprehensive consideration of surgical options is warranted, with caution exercised in selecting BCT. While overall survival (OS) rates were comparable between the two groups in young women, further research is warranted to elucidate these findings and guide clinical decision-making. [1-3]
Exploring the Knowledge Levels of Bankers on Health Risks of Overweight and Obesity
Authors: Jonathan Justice Wiston Amstrong , Baba Stephen , Etornam Kezia Kwawudade , Abambila Solomon , Gyan Charity , Okonkwo Ifunanya Chinenye
Published: August 2024

Background: Overweight and obesity are becoming serious public health menace in the world today. Weight gain is skyrocketing across the globe due to growing economy, fast food expansion and a shift towards more sedentary living. However, most people lack knowledge regarding risks associated with overweight and obesity.
Aim: The study aimed to explore the knowledge level of bankers in the Ho Municipality on the health risks associated with overweight and obesity.
Methodology: A cross-sectional study design with quantitative method was employed. The study spanned from September 7, 2018 to April 25, 2019. A self-administered questionnaire and convenience sampling technique were used to obtain data. Data were analysed using IBM SPSS Statistics 21 Developer and the results presented in statistical tables and graphs.
Results: Of 136 participants investigated, 67 (49.3%) were between 31 - 40 years. 2 participants (1.5%) were underweight, 49(36.0%) had normal weight, 43(31.6%) were overweight while 42 (30.9%) were obese. The study revealed that female bankers were prone to overweight (37.78%) while the males were prone to obesity (56.52%). Participants generally had low knowledge and awareness on health risks of overweight and obesity.
Conclusion: Most bankers in the Ho Municipality were overweight and obese due to insufficient knowledge and low awareness on the risks associated with overweight and obesity. Public education and awareness creation are urgently needed to stem the tide.
Physician preparedness for genetic counseling in a pediatric cancer center in Egypt
Authors: Gouda Nouran , Haddad Alaa El , Maher Eslam , Koeller Diane , Maga Tara , McQuaid Shelly
Published: August 2024

Purpose: Considering the significant frequency of consanguinity in Egypt, a large portion of its childhood cancers may have an underlying hereditary component. The preparedness of physicians in the pediatric cancer setting to collaborate with genetic counselors is vital to provide the needed care.
Methods: We conducted a cross-sectional survey aiming to evaluate the level of genetic counselling knowledge and awareness among Egyptian physicians in a large pediatric cancer center, and the barriers they perceive to its implementation.
Results: A total of 150 physicians were invited, of which, 52 responded to the questionnaire. Most of the participants were oncologists (86.5%), and 9.6% were from other subspecialties such as surgery, pathology, and radiology. The majority had practical exposure to genetics in clinic with 75% (39/52) reporting involvement in a case with hereditary cancer syndrome. The average knowledge score (SD) was 42.1 (6.9) out of 60. Knowledge scores were greater in those who had educational exposure to genetics. Most of the participants (76%) incorrectly agreed that a purpose of genetic counseling is to advise people on whether to have children. A sizeable portion (21%) didn’t know the type of training or education that a genetic counselor acquires. Overall, attitudes towards genetic counseling were positive. The most perceived barrier (42%) was their referral to an MD geneticist or other physician specialist for genetics related indications.
Conclusions: Egyptian physicians working in pediatric cancer care have moderate familiarity with genetic risk assessment and recognize its value. However, there is a difficulty in discerning the specific tasks performed by genetic counselors and how they can be integrated in the clinical framework.
Prevalence of stimulants among students of the Syrian Private University and its relationship with academic achievement and psychological state
Authors: Eteish Hazem Ahmad , ALetesh Ahmad Nashmi
Published: August 2024

Background: Non-medical use of neuropharmaceuticals generates significant discussions in medical and public health circles. The main motivation for this non-medical use of neuropharmaceuticals is to enhance cognitive function in healthy individuals beyond normal human capacity. Objective: The prevalence of stimulants among Syrian Private University students and its relationship with academic achievement and psychological status.
Methods: A cross-sectional study conducted at the Syrian Private University, during the period 12/1/2023 to 7/1/2024. The students' responses, numbering 386 male and female students, were studied through an electronically distributed questionnaire.
Results: The sample consisted of 386 students. With an average age of 22.40 years. The percentage of males was 51% compared to females 49%. The financial status was average at 40%. The students of the Faculty of Human Medicine constituted the largest number of students in the sample, reaching 45%. The most common reason for using these stimulants among the students who used them was staying up late and studying during exams and projects, which was 5% of the students. The fourth year was the highest year in terms of stimulant use among the students, with a rate of 4%. The students of the Faculty of Human Medicine were the students who had the highest anxiety score, which was 1.93 compared to the students of the other faculties.
Conclusion: The percentage of stimulant use among the students in our study was 8% of the total students. The most frequent motives for using stimulant drugs were reasons related to academic activities. The results of our study differed regarding the students' knowledge of stimulants and their side effects, as only 3% of the students in our study indicated their knowledge of these drugs and their side effects.
Magnetic collapse and low conductivity of Fe3N in the deep interiors of Earth-like planets
Authors: Zhuang Yukai , Liu Jin , Lv Chaojia , Xu Liangxu , Bi Wenli , Hu Qingyang , Zhang Dongzhou , Garbarino Gaston , Zhu Shengcai , Zhang Youjun
Published: August 2024

The high-pressure behavior of iron nitrides has garnered significant attention due to the possibility of deep nitrogen reservoirs within the Earth’s interior. Here, we investigate the magnetic, structural, electrical, and thermal properties of Fe3N up to 62 GPa and 2100 K, using multiple probes coupled with the diamond-anvil cell technique (including synchrotron X-ray diffraction, synchrotron Mössbauer spectroscopy, and electrical measurements). Fe3N undergoes a magnetic phase transformation from the ferromagnetic to paramagnetic state at ~17-20 GPa, 300 K. The equation of state was determined as, V0/Z = 42.8(1) Å3, and K0 = 151.8(1) GPa, with K′ fixed at 4. Additionally, Fe3N exhibits unexpectedly low electrical and thermal conductivity under high-pressure and high-temperature conditions. This result suggests that deep nitrogen cycling may contribute to the thermal evolution of the deep interiors of Earth and other terrestrial bodies.
Analogues and Derivatives of Cannabidiol: Pharmacological Insights and Recent Efforts in the Search for Novel Drug Candidates for Inflammation and Pain - a Brief Review Over the Past 3 Decades
Authors: L. de Souza Mikaela , R. R. Franco Graziella , E. Massuda Larissa , S. Gontijo Vanessa , Viegas Jr. Claudio
Published: August 2024

Cannabidiol is a metabolite present in Cannabis with several pharmacological properties, including neuroprotection, anti-convulsive, antimicrobial, antinociceptive, and anti-inflammatory. Although these activities are promising for drug development and clinical uses, the neuroprotective action is the most investigated, while the anti-inflammatory and antinociceptive mechanisms are not fully known. Therefore, this brief review aims to report the knowledge advances over the last 3 decades regarding the anti-inflammatory and anti-nociceptive/analgesic properties of cannabidiol and its derivatives or analogues designed as novel drug candidates. Recent studies of the mechanisms of action underlying the anti-inflammatory effects of cannabidiol have revealed its interaction with different inflammatory mediators, including cannabinoid receptor 1 and cyclooxygenase 2, among others. On the other hand, there is a lack of information related to the analgesic activity of cannabidiol, with some reports pointing out the involvement only of transient receptor potential vanilloid receptors. In addition, several cannabidiol derivatives and structural analogues with anti-inflammatory and antinociceptive activities have been described, but their mechanisms of action have not yet been fully elucidated. Therefore, it is clear that greater efforts are still needed to unravel the mechanisms involved in such activities of great interest in drug discovery.
Investigation of the predictive factors of recurrent ovarian mucinous cystadenoma
Authors: Ozcan Aykut , Balikoglu Meric , Alkan Kaan Okan , Gulseren Varol
Published: August 2024

OBJECTIVE: Rapid growth patterns and recurrence with variable rates have been reported in the literature, making mucinous cystadenomas different from other ovarian benign neoplasms. The study aimed to predict and prevent recurrence based on the obtained results.
STUDY DESIGN: In this case-control study among the 2,341 patients who underwent surgery for ovarian cysts, 221 met the inclusion criteria. The 221 patients diagnosed with mucinous cystadenoma were categorized into two groups: 14 patients (6.3%) with recurrence and 207 patients (93.7%) without recurrence. Patients in these groups were compared in terms of demographic characteristics, ovarian cyst size, operative technique, type of surgery (oophorectomy or cystectomy), Ca19-9, CA125, and CEA values of the patients, and duration of postoperative follow-up.
RESULTS: The mean age was statistically lower in the group with recurrence (27 ± 5 vs 44 ± 14; p<0.001). The follow-up period of recurrent cases was significantly longer (6.8 ± 3.5 vs 4.9 ± 2.2 years; p=0.045). The recurrence rate was significantly higher in patients who underwent cystectomy (p<0.001; odds ratio: 22.8). When all patients were examined, cystectomy was preferred in younger patients [31 (18-65) vs 48 (18-81); p<0.001]. According to regression analysis, cystectomy alone is an independent risk factor (p=0.041).
CONCLUSION: Unlike conventional ovarian cystadenomas, mucinous cystadenomas should be followed up owing to the possibility of recurrence, especially when detected at an early age. Since cystectomy is the only independent risk factor, oophorectomy should be the primary treatment for patients >40 years of age who have no desire for childbearing.
Colecciones de historia natural y fauna poco estudiada: Pinctada longisquamosa (Bivalvia) en el Caribe colombiano
Authors: Gracia Adriana , Navarrete Rodríguez David Alejandro
Published: August 2024

La ostra perlera escamosa, Pinctada longisquamosa (Margaritidae), reside en hábitats marinos poco profundos dentro de la región del Atlántico occidental tropical desde Florida hasta Venezuela. Esta especie permaneció sin ser reconocida durante un período prolongado debido a la frecuente identificación errónea con otras especies de ostras del Atlántico occidental como Pinctada imbricata, o la especie de Pteriidae, Pteria colymbus. En este estudio, establecemos su presencia confirmada en el Caribe colombiano con base en especímenes almacenados y sin catalogar en la colección de moluscos del Museo de Historia Natural Marina – Makuriwa – en Santa Marta, Colombia. Todos los ejemplares fueron recolectados de raíces de manglar. Este descubrimiento subraya el papel invaluable de los museos de historia natural en la documentación de patrones de distribución biogeográfica y aporta un registro comprobado a la fauna malacológica marina de Colombia.
Current Concepts and Limits of Cell-Based Regeneration Strategies for Degenerative Disc Disease
Authors: Dowling Alvaro , Molina Marcelo , López William Omar Contreras , Lorio Morgan P. , Landgraeber Stefan , León Jorge Felipe Ramírez , Lewandrowski Kai-Uwe
Published: August 2024

Degenerative disc disease stands as the predominant etiological factor
behind low back pain. In recent years, the therapeutic modality of mesenchymal stem
cell (MSC) infusion directly into the nucleus pulposus of the deteriorating disc has
gained prominence. The intricacies of the intervertebral disc, a biomechanically robust
tissue, span its components - the annulus fibrosus, nucleus pulposus, and cartilaginous
endplates. Compromising the integrity of these elements can precipitate advanced disc
degeneration due to biomechanical disruption. Animal models have demonstrated the
therapeutic potential of MSCs. Particularly, adipose-derived stem cells (ASCs), a
subset of MSCs originating from adipose tissue, possess attributes akin to their bone
marrow-derived counterparts, metamorphosing into mesodermal structures,
encompassing bone, cartilage, muscle, and fat. Their abundance in the human system, coupled with minimally invasive extraction methods, makes them appealing for
regenerative medicine applications. A comprehensive literature assessment presented in
this chapter delineates the therapeutic paradigm of MSCs in addressing degenerative
disc disease (DDD) pain. To date, research predominantly centered on the nucleus
pulposus, while neglecting the annulus fibrosus and cartilaginous endplates. Notably,
clinical manifestations like annular ruptures, Modic alterations, or Schmorl's nodal
formations typically hint at pathologies within these overlooked structures. The
prospects of successful regenerative interventions within the annulus, endplates, or
nucleus pulposus remain controversial, considering the hostile, nutrient-deprived
milieu of the deteriorating intervertebral disc often culminating in the swift demise of
the introduced MSCs. Singularly targeting the compromised nucleus pulposus via
existing MSC-centric regenerative modalities may not achieve disc restoration.
Therefore, MSC-based theurapeutic strategies should not just include the nucleus
pulposus but also the affected annulus fibrosus and cartilaginous endplates.
Ultrasound-Guided and Single Portal Endoscopic Carpal Tunnel Release
Authors: Lorio Morgan P. , Paterson Paul
Published: August 2024

As surgeons evolve to minimize morbidity and maximize outcomes or
return-to-work (RTW) in the treatment of carpal tunnel syndrome (CTS), so have both
single portal neuro-endoscopy and ultrasound-guided (US) technical applications
procedurally in the safe, effective, and complete release/transection of the transverse
carpal ligament (TCL). The chapter is intended as an independent complete go-to
content-repository for surgeons desiring to revisit/review a relevant topic or area of
thought without needing to reread the entirety of the same prior to a surgical case as a
quick refresher. For those surgeons who have either mastered neuro-endoscopy or
remain a novice, US techniques may offer patients new possibilities through the simple
overlay of novel instruments and instructions over one’s accumulated past experience.
Konstruksi Ideal Badan Regulasi Nasional Dalam Bingkai Hukum Positif Indonesia
Authors: Mahdi Wahyu Laksana , Qurbani Indah Dwi , Susmayanti Riana
Published: August 2024

Mandate of Law Number 15 of 2019 concerning Amendments to Law Number 12 of 2011 concerning the Establishment of Laws and Regulations which mandates the establishment of ministries or institutions that carry out government affairs in the field of forming laws and regulations. However, until December 2023, the ministry or institution that the author further proposes the nomenclature of the National Regulatory Agency has not yet been formed and has implications for the legal certainty aspect of the establishment of the institution. In addition, the a quo law also does not provide a complete regulatory concept for the institutional format to be regulated in the Presidential Regulation. Based on this, this study raises the formulation of the problem (1) how is the legal politics of the establishment of the National Regulatory Agency in Indonesia? and (2) what is the regulatory concept for the establishment of the National Regulatory Agency in the Indonesian legal system? Then, this research uses normative juridical methods using statutory approaches and conceptual approaches. Legal materials used include primary, secondary and tertiary legal materials with legal material tracing techniques, namely literature studies and internet media. Therefore, there is a need for the concept of institutional arrangements which in this case the author formulates into 4 (four) main things. First, the regulation of the National Regulatory Agency through a Presidential Regulation. Second, the organizational structure of the National Regulatory Agency. Third, the National Regulatory Agency. Fourth, the accountability pattern of the National Regulatory Agency.
Analisis Pengaturan Hak Untuk Dilupakan Bagi Anak Korban Tindak Pidana Kekerasan Seksual di Indonesia
Authors: Salsabil Maisarah , Solehuddin Solehuddin , Noerdajasakti Setiawan
Published: August 2024

The growing incidence of sexual violence in Indonesia has taken children as the victims with the highest number of cases among other cases with victims of other age groups. This problem is alarming, considering that it may threaten the future generations of the nation, contrary to the fact that children must receive special protection. Law Number 12 of 2022 concerning Sexual Violence as a Crime implies that children as the victims of sexual violence are entitled to the right to be taken care of and the right to recovery, in which electronic information and/or documents regarding the violence that the children concerned have suffered from must be deleted. In other words, children should be entitled to the right to be forgotten. This research employed a normative-juridical method and statutory, conceptual, and comparative approaches. The legal materials involved primary and secondary data, obtained from library research. The research results reveal that the Law concerning Sexual Violence Crime has loopholes regarding the right to be forgotten of children as the victims of sexual violence, especially in the scope of the subject matter and the mechanism of the actualization of the right to be forgotten for the children concerned. In other words, this matter needs to be further regulated. Therefore, the Law concerning Sexual Violence Crime needs improvement for a comprehensive regulation of the mechanism of the right to be forgotten for children.
Tendencias investigación en levaduras y su efecto antimicrobial en Salmonella, Escherichia coli y Campylobacter
Authors: Contreras Pedraza Carlos Alberto
Published: August 2024

El objetivo de estudio es identificar a través de la vigilancia científica y tecnológica, como herramientas para la gestión de información especializada, las tendencias en investigación en el entorno mundial sobre los efectos antimicrobiales de las levaduras sobre los patógenos: Salmonella, Escherichia Coli y Campylobacter. El documento se estructura en cinco secciones, correspondientes con el uso e implementación de herramientas para el tratamiento y análisis de la información científica disponible en las bases de datos especializadas. Las secciones son a saber: i) Generalidades y metodología; ii) indicadores de impacto del objeto de estudio; iii) análisis cienciométrico; iv) paisajes científicos y clusterización; y, v) Análisis de patentes.
Physiology-Driven Reversible Dynamic Synthetic Tissue Model for Responsive Moulage in Infected Wound Training (Preprint)
Authors: Gong Alex T , DeSchmidt Aleah M , Baird Austin J , Gonzaga Jessica G , Yau Shi-Wen Olivia , Toepfer Rudolph J , Zhang Jessica , Parsey Conner J , Leuschke Rainer , Norfleet Jack E , Sweet Robert M
Published: August 2024

BACKGROUND

Misidentification of dermatologic manifestations of systemic infection can lead to life-threatening developments including sepsis.

OBJECTIVE

Training medical providers to accurately identify and respond to infections using simulation could reduce these rates. Moulage of infections are static and require a manual “scene change” during simulation scenarios.

METHODS

A high-fidelity, automated physiology-driven dynamic infection model was developed using the Modular Healthcare Simulation and Education platform that physically changes to simulate the progression of an infected wound. The silicone model was designed using resistive wire, wax actuators, and thermochromic powder. The resistive wire heats the wax, resulting in focal edema, skin warmth, and erythema that reverses with proper recognition and treatment. Without external treatment, purulence is released, and the patient will develop septic physiology. To evaluate the physiological realism and training value of the model, a survey of physicians was conducted using a five-point Likert scale of agreement with 5 being the highest rating

RESULTS

When asked to rate the realism of the model, the mean response was 4.1 ± 0.7. When asked if they thought the model had value for training infection identification, the mean response was 4.3 ± 0.9. Finally, when asked if the dynamic aspect would improve the simulation, the mean response was 4.7 ± 0.6.

CONCLUSIONS

The dynamic infection model is functional and appealing for practitioners to assist in the early detection of infection. The use of a dynamic training model could potentially be used to replicate other dermatologic manifestations of systemic disease processes and improve medical training.
Аналитическое и пробоподготовительное оборудование SUNDY
Authors: Назимов С.А.
Published: August 2024

Более 10 лет «Группа Ай-­Эм-­Си» поставляет аналитическое оборудование для промышленности и научных исследований. Специалисты компании предлагают индивидуальные технические решения, устанавливают и планово обслуживают оборудование. При необходимости разрабатывают методики анализа и измерений, проводят обучение персонала заказчика и внедрение приборов в практику. Одним из направлений деятельности компании «Группа Ай-­Эм-­Си» является поставка, запуск в эксплуатацию и обслуживание аналитического оборудования китайской компании Hunan Sundy Science and Technology Co.
НСАМ: 60 лет на службе качества лабораторных исследований минерального сырья
Authors: Лебедева М.И. , Рогожин А.А.
Published: August 2024

В 2024 году Научному совету по аналитическим методам (НСАМ) исполняется 60 лет. В статье отмечен неоценимый вклад основателей совета в создание и развитие системы управления качеством аналитических работ в геологической отрасли, обеспечение достоверности и сопоставимости лабораторных исследований минерального сырья. Приведен обзор руководящих документов, устанавливающих требования к основным этапам проведения аналитических работ – от отбора проб до всех видов контроля качества выполнения анализа горных пород и руд. Рассмотрены ключевые блоки Системы УКАР: методики измерений, стандартные образцы, межлабораторные сравнительные испытания, подтверждение компетентности лабораторий.
Uso de los tiempos verbales en narraciones infantiles
Authors: Peña Ramos Amor Madai , González Márquez Verónica
Published: August 2024

La presente investigación busca establecer los cambios que se producen en los usos de los tiempos verbales en dos tipos de narraciones de niños en etapa tardía de adquisición: cuento a partir de imágenes y recuento. Para el análisis, se segmentaron las narraciones en cláusulas y se clasificaron los tiempos verbales (Rojo Veiga, 1999). Se clasificaron los tiempos verbales de acuerdo con las propuestas de Weinrich (1974) y Bassols y Torrent (1997) y las cláusulas según la sección de la estructura narrativa (Labov Waletzky, 1967). En los resultados se nota una diferencia de acuerdo con el estímulo empleado para elicitar las narraciones. El pretérito es el único tiempo verbal presente en todas las secciones de la estructura narrativa de narraciones del corpus de cuento a partir de imágenes, que sugiere que la mayoría de las acciones se presentan como eventos completos, lo que confiere a la narración un carácter retrospectivo. Por su parte, en el corpus de recuento, el co–pretérito es el único tiempo que se encuentra en todas las secciones de la estructura narrativa, lo que sugiere que se trata de eventos pasados que conducen a la complicación principal de la historia.
Manual para la evaluación ciudadana de los suelos y la vegetación de Guerrero
Authors: Figueroa Daniela , Navarrete Segueda Armando , Avilés Junco Carolina , Aguas Pérez Elizabeth , Cortés Flores Jorge , Mora Palomino Lucy , Cayetano Salazar Mario , Lopezaraiza Mikel Martha , Sáyago Lorenzana Roberto Carlos , Prado Pano Blanca Lucia , klimek Alcaraz Octavio Adolfo
Published: August 2024

Este manual se elaboró con el espíritu de sumar a los trabajos de diagnóstico y rescate ambiental de zonas afectadas por el huracán Otis en Guerrero. Se enfoca en la evaluación del suelo y la vegetación como componentes de los ecosistemas que proveen servicios ecosistémicos o contribuciones de la naturaleza que sostienen la vida en el planeta; por ejemplo, la infiltración del agua, producción de oxígeno, almacenamiento de carbono, hábitat de la biodiversidad, control de la erosión, polinización, producción de cultivos, control de plagas y valores culturales asociados.
Wordsworth’s Environmental Philosophy: The Interconnection of Humanity and Nature in “Lines Composed a Few Miles Above Tintern Abbey”
Authors: Soni Jyoti
Published: August 2024

Abstract: This study delves into William Wordsworth’s environmental philosophy as articulated in his poem “Lines Composed a Few Miles Above Tintern Abbey,” focusing on the intricate interconnection between humanity and nature. Wordsworth’s work is a cornerstone of Romantic literature, emphasizing the profound relationship humans share with the natural world. Through a close reading of the poem, this study explores how Wordsworth perceives nature as a source of spiritual renewal, moral guidance, and emotional solace. The poet reflects on his own experiences and memories, illustrating how nature’s beauty and tranquility influence his inner life and philosophical outlook. Wordsworth’s reverence for nature is not merely aesthetic but also deeply ethical, suggesting that harmony with nature fosters self-awareness and ethical living. The poem underscores the transformative power of nature to heal and elevate the human spirit, advocating for a reciprocal relationship between people and their environment. By examining the themes of memory, reflection, and transcendence in the poem, this study highlights Wordsworth’s vision of nature as an essential counterpart to human existence, urging a reawakening to the interconnectedness that sustains both ecological and human well-being. This analysis contributes to a broader understanding of Wordsworth’s enduring legacy in environmental thought and Romantic literature
Enhancing the Campbell-Oblinger Model: Integrating Generative AI at Each Step of Learning Analytics
Authors: Marade Anish
Published: August 2024

Abstract: This paper explores the potential of Generative Artificial Intelligence (GenAI) to revolutionize learning analytics by integrating it into each stage of the Campbell-Oblinger Five- Step Model. This model, renowned for its comprehensiveness and flexibility, provides a robustframework for implementing learning analytics across diverse educational settings. This research investigates the specific applications of GenAI at each stage of the model, including data capture, reporting, prediction, intervention, and refinement. Additionally, this paper performs a comparative analysis between traditional human-driven approaches and their corresponding GenAI benchmarks, highlighting the potential benefits and challenges associated with GenAI integration. By examining the transformative potential of GenAI within the framework of the established CampbellOblinger model, this study aims to contribute valuable insights to the field of learning analytics and inform future research endeavors.
Abordar las semiosferas a partir de listas de canciones: semiótica de las playlists
Authors: Moreno Sebastián
Published: August 2024

Este artículo utiliza una perspectiva semiótico-cultural para examinar cómo las playlists musicales pueden ser de utilidad para definir y caracterizar una semiosfera dada. El texto comienza con una discusión sobre la semiótica cultural y el desafío analítico de acceder a una semiosfera a través de la música. Luego, se centra en el papel que desempeñan las listas al definir, describir y caracterizar una semiosfera dada. Finalmente, se aborda cómo las playlists musicales —esto es, colecciones de canciones agrupadas siguiendo una regla o criterio— pueden definir y caracterizar una semiosfera. La sección analítica del artículo estudia tres tipos generales de semiosferas vinculadas a (1) el espacio, (2) el tiempo y (3) las identidades colectivas.
Nota: Este artículo fue publicado originalmente en inglés en el año 2023 con el título “Approaching Semiospheres Through Lists of Songs: The Semiotics of Musical Playlists”, en la revista Punctum, 9(1), pp. 13-29. DOI 10.18680/hss.2023.0002. La traducción del inglés al español —que solo presenta algunos cambios formales y una adenda final como modificaciones a la versión original— fue realizada por su autor.
Relationships between Attitude Toward Physical Education and Physical Activity Levels in Chinese Middle School Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Yu Yangzhao , Lee Ansu , Choi Seungwoo , Park Sungki , Liu Shuangrui
Published: August 2024

Objectives The purposes of this study were to investigate the attitudes toward physical education and physical activity levels of middle school students in Jiangxi Province, China, and explore the relationship between these two factors.
Methods The subjects consisted of 722 middle school students (male: 371 and female: 351) from 7th to 9th grade at four public middle schools in Jiangxi Province, China. The measurement tools were used the Chinese version of Students' Attitude Toward Physical Education (Hu et al., 2014) and the Chinese version of Physical Activity Questionnaire for Adolescents (Li, 2015). For data analysis, confirmatory factor analysis (CFA), descriptive statistics, univariate analysis of variance (ANOVA), multivariate analysis of variance (MANOVA) were performed, using SPSS 26 and AMOS 27 statistical program.
Results The results showed that first, participants' attitudes toward physical education were generally positive across all grades and genders, with average scores above 3.0 for all sub-factors. According to the result of MANOVA, gender had a significant impact on all dependent variables [CE: F(1, 716)=21.795, p<.05; CU: F(1, 716)=14.818, p<.05; TE: F(1, 716)=18.150, p<.05; TU: F(1, 716)=8.130, p<.05]; however, grade did not significantly affect attitudes. Second, physical activity levels varied by gender and grade, with males generally exhibiting higher (2.34) scores than females (1.88). According to a multivariate analysis of variance (MANOVA), both gender [F(1, 716)=80.342, p＜.05] and grade [F(2, 716)=24.351, p＜.05) had significant effects on physical activity scores, while the interaction effect between grade and gender was not significant [F(2, 716)=1.659, p＞.05]. Third, correlation analysis revealed slightly positive relationships between physical activity and the four sub-scales of attitude [CE (r=.290, p<.05); CU (r=.299, p<.05); TE (r=.326, p<.05); TU (r=.283, p<.05)].
Conclusions The results of this study are expected to enhance the understanding of middle school students by schools and physical education teachers for the development of physical education in China, and to contribute to the development of future physical education programs by providing theoretical evidence.
A Study on the Pre-service Early Childhood Teachers' Perceptions of Digital Media Literacy: with a focus on metaphor analysis and FGI
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Yun So Yeong , Lee Sang Seon
Published: August 2024

Objectives This study explored pre-service early childhood teachers' perceptions of digital media literacy through metaphor analysis and sought to gain implications for preservice teacher education.
Methods For this purpose, D and K also conducted a survey of 157 students in the Department of Childhood and Early Childhood Education. The metaphor analysis questionnaire consisted of the following sentences: ‘Digital media literacy of early childhood teachers is . Because .’ The questionnaire consisted of the following statements. To ensure the validity of the metaphor analysis results, FGIs were conducted with eight participants, and the survey and interview data were categorized according to Moser's (2000) methodological procedures.
Results Pre-service early childhood teachers most often perceive digital media literacy as an important and essential skill for teachers because it enables them to guide children and young people in the appropriate use of digital media. On the other hand, they are concerned that the increased importance of digital media literacy competencies will increase their responsibilities and burdens as teachers.
Conclusions This study suggests that pre-service early childhood teacher education programs should be supplemented to ensure that pre-service early childhood teachers have a sound understanding of digital media literacy and to address their fears about building digital media literacy competencies.