bluuebunny/crossref_metadata_2025 huggingface dataset:
Rapid and easy construction of a simplified amplicon sequencing (simplified AmpSeq) library for marker-assisted selection
Authors: Nishio Sogo , Moriya Shigeki , Kunihisa Miyuki , Takeuchi Yukie , Imai Atsushi , Takada Norio
Published: June 2023

Marker-assisted selection (MAS) is fundamental for plant breeding programs, as it can identify desirable seedlings at a young stage and reduce the cost, time and space needed for plant maintenance, especially for perennial crops. To facilitate the process of genotyping, which is time consuming and laborious, we developed a simplified amplicon sequencing (simplified AmpSeq) library construction method for next-generation sequencing that can be applied to MAS in breeding programs. The method is based on one-step PCR with a mixture of two primer sets: the first consisting of tailed target primers, the second of primers that contain flow-cell binding sites, indexes and tail sequences complementary to those in the first set. To demonstrate the process of MAS using s implified AmpSeq, we created databases of genotypes for important traits by using cultivar collections including triploid cultivars and segregating seedlings of Japanese pear (Pyrus pyrifolia Nakai), Japanese chestnut (Castanea crenata Sieb. et Zucc.) and apple (Malus domestica Borkh.). Simplified AmpSeq has the advantages of high repeatability, ability to estimate allele number in polyploid species and semi-automatic evaluation using target allele frequencies. Because this method provides high flexibility for designing primer sets and targeting any variant, it will be useful for plant breeding programs.
Entropic barrier of water permeation through single-file channels
Authors: Wachlmayr Johann , Fläschner Gotthold , Pluhackova Kristyna , Sandtner Walter , Siligan Christine , Horner Andreas
Published: June 2023

Facilitated water permeation through narrow biological channels is fundamental for all forms of life. Despite its significance in health and disease as well as for biotechnological applications, the energetics of water permeation are still elusive. Gibbs free energy of activation is composed of an enthalpic and an entropic component. Whereas the enthalpic contribution is readily accessible via temperature dependent water permeability measurements, estimation of the entropic contribution requires information on the temperature dependence of the rate of water permeation. Here, we estimate, by means of accurate activation energy measurements of water permeation through Aquaporin-1 and by determining the accurate single channel permeability, the entropic barrier of water permeation through a narrow biological channel. Thereby the calculated value for $$\triangle {S}^{{{\ddagger}} }$$
△

S

‡

 = 2.01 ± 0.82 J/(mol·K) links the activation energy of 3.75 ± 0.16 kcal/mol with its efficient water conduction rate of ~1010 water molecules/second. This is a first step in understanding the energetic contributions in various biological and artificial channels exhibiting vastly different pore geometries.
Real-time latent heat emission during dynamic-compression freezing of water
Authors: Nissen Erin J. , La Lone Brandon M. , Mance Jason G. , Larson Eric , Dolan Daniel H.
Published: June 2023

Dynamic compression studies have been used to study the nucleation kinetics of water to ice VII for decades. Diagnostics such as photon Doppler velocimetry, transmission loss, and imaging have been used to measure pressure/density, and phase fraction, while temperature has remained the difficult thermodynamic property to quantify. In this work, we measured pressure/density and implemented a diagnostic to measure the temperature. In doing so the temperature shows quasi-isentropically compressed liquid water forms ice at pressures below the previously defined metastable limit, and the liquid phase is not hypercoooled as previously thought above that limit. Instead, the latent heat raises the temperature to the liquid-ice-VII melt line, where it remains with increasing pressure. We propose a hypothesis to corroborate these results with previous work on dynamic compression freezing. These results provide constraints for nucleation models, and suggest this technique be used to investigate phase transitions in other materials.
Paleobathymetric reconstructions of the SW Barents Seaway and their implications for Atlantic–Arctic ocean circulation
Authors: Lasabuda Amando P. E. , Hanssen Alfred , Laberg Jan Sverre , Faleide Jan Inge , Patton Henry , Abdelmalak Mansour M. , Rydningen Tom Arne , Kjølhamar Bent
Published: June 2023

Unravelling past, large-scale ocean circulation patterns is crucial for deciphering the long-term global paleoclimate. Here we apply numerical modelling to reconstruct the detailed paleobathymetry-topography of the southwestern inlet of the Barents Seaway that presently connects the Atlantic and Arctic oceans. Subaerial topography was likely enough to block Atlantic Water from entering the Barents Seaway in the earliest Eocene (c. 55 Ma). The water may have entered in the middle Eocene (c. 47 Ma) as observed from major basin subsidence, but paleotopographic highs to the east may have hindered connections between the two oceans. From the Oligocene (c. 33 Ma) until the onset of the Quaternary (c. 2.7 Ma), basin shallowing and regional shelf uplift blocked Atlantic Water from entering the Barents Seaway. Our results imply that the Fram Strait remained the sole gateway for Atlantic Water into the Arctic Ocean since its opening in the Miocene until the Quaternary.
Bridging arsolido complexes
Authors: Kirk Ryan M. , Hill Anthony F.
Published: June 2023

The first examples of heterobimetallic μ-arsolyl complexes with unsupported metal–metal bonds are described.
Retraction: Bis-salophen palladium complex immobilized on Fe3O4@SiO2 nanoparticles as a highly active and durable phosphine-free catalyst for Heck and copper-free Sonogashira coupling reactions
Authors: Reza Sardarian Ali , Kazemnejadi Milad , Esmaeilpour Mohsen
Published: June 2023

Retraction of ‘Bis-salophen palladium complex immobilized on Fe3O4@SiO2 nanoparticles as a highly active and durable phosphine-free catalyst for Heck and copper-free Sonogashira coupling reactions’ by Ali Reza Sardarian et al., Dalton Trans., 2019, 48, 3132–3145, https://doi.org/10.1039/C9DT00060G.
Successful prediction for coagulant dosage and effluent turbidity of a coagulation process in a drinking water treatment plant based on the Elman neural network and random forest models
Authors: Wang Dongsheng , Chen Le , Li Taiyang , Chang Xiao , Ma Kaiwei , You Weihong , Tan Chaoqun
Published: June 2023

The uncertainty of the changes in the quality of raw water, and the long lag in the process of coagulation introduce significant difficulties in eliminating turbidity during the treatment of drinking water.
Study on drying kinetics, antioxidant activity, total bioactive compounds, physicochemical properties and microstructural characteristics of dehydrated star fruits (Averrhoa carambola) by different drying methods
Authors: Dhara Jayanti , Saha Suman kumar , Saha Madhumita , Chakraborty Runu
Published: June 2023

Drying ensures an uninterrupted supply of highly perishable and seasonal fruits such as star fruit (Averrhoa carambola).
Biological and postharvest interventions to manage the ethylene in fruit: a review
Authors: Asrey Ram , Sharma Swati , Barman Kalyan , Prajapati Uma , Negi Narender , Meena Nirmal Kumar
Published: June 2023

(A) Ethylene biosynthesis and perception mechanism in fruits and vegetables and possible interventions to control the ethylene; (B) CRISPR/Cas 9 gene editing tool to manage ethylene in perishables.
Ginsenoside-Rg1 synergized with voluntary running exercise protects against glial activation and dysregulation of neuronal plasticity in depression
Authors: Wang Wenjing , Wang Lihong , Wang Liyan , Li Ye , Lan Tian , Wang Changmin , Chen Xiao , Chen Shihong , Yu Shuyan
Published: June 2023

Ginsenoside-Rg1 synergized with voluntary running exercise exert neuroprotective effects and ameliorate depression-like behaviors.
Synthesis of violet phosphorus with large lateral sizes to facilitate nano-device fabrications
Authors: Wang Yanhao , Jin Mengting , Gu Mengyue , Zhao Xuewen , Xie Jinan , Meng Guodong , Cheng Yonghong , He Jinjiang , Zhang Jinying
Published: June 2023

Violet phosphorus plates with large lateral sizes are produced by a molten lead method to facilitate mechanical exfoliation and nano-device fabrication.
Anomalous transmission and Anderson localization for alternating propagated and evanescent waves at the deep-subwavelength scale
Authors: Sun Changlin , Liu Haiyi , Qi Pengfei , Zhu Liguo , Guo Lanjun , Lin Lie , Liu Weiwei
Published: June 2023

The previously reported broken effective-medium theory is still convincing and the anomalous transmission is reasonable after a simple correction. The ‘anomalous’ transmission can be effectively modulated by introducing disorder.
Multibranched triarylamine end-capped oxime esters as visible-light absorbing type I photoinitiators for free radical photopolymerization
Authors: Wu Yu-Hao , Noon Adel , Hammoud Fatima , Hamieh Tayssir , Toufaily Joumana , Graff Bernadette , Lalevée Jacques , Chen Yung-Chung
Published: June 2023

Compounds (TPA-DP, TPA-CZ and TPA-PT) had been developed and synthesized, in which three electron-donating groups (diphenylamine, carbazole, or phenothiazine) are connected to the 4,4′-positions of the triphenylamine to form three triarylamine oxime ester photoinitiators.
Suppression and utilization of Kasha's rule: realizing the transformation from blue to near-infrared emission
Authors: Xie Mingchen , Cai Jia-Heng , Zhang Guangyu , Jung Sinyeong , Dong Dongfang , Zhang Zhao-Yang , Zhou Dong-Ying , Liao Liang-Sheng , Li Tao
Published: June 2023

Phenoxazine–phenazine exhibits variable emission by suppressing and utilizing Kasha's rule and demonstrates both dual emission and near-infrared emission. This significant mechanism related to Kasha's rule would be advantageous in various fields.
Efficient multigram procedure for the synthesis of large hydrazone-linked molecular cages
Authors: Vestrheim Olav , Schenkelberg Mica E. , Dai Qingsheng , Schneebeli Severin T.
Published: June 2023

An efficient pathway to synthesize covalent hydrazone-linked molecular tetrahedra is reported. Our new synthesis enabled us to create a family of hydrolytically stable organic molecular cages with large openings required to bind complex guests.
Lignin-first biorefinery approach for the valorization of cotton stalks to phenolic monomers
Authors: Jindal Meenu , Kumar Adarsh , Rawat Shivam , Thallada Bhaskar
Published: June 2023

Cotton stalks were fractionated using a lignin-first biorefinery approach by converting lignin to phenolic monomers and carbohydrates to functional carbon(s).
Understanding the role of interfacial layers in the photostability of PM6:Y7-based organic solar cells under different degradation conditions
Authors: Ramírez-Como Magaly , Moustafa Enas , Samir Mohamed , Torimtubun Alfonsina Abat Amelenan , Sánchez José G. , Pallarès Josep , Marsal Lluis F.
Published: June 2023

At present, low long-term stability is the main limitation for organic solar cells. The origin of the degradation of high-efficiency non-fullerene solar cells by impedance spectroscopy and its degradation mechanisms has been investigated.
Developing single silane-derived delayed fluorescent carbon dots as donors for energy transfer-based aqueous-phase multicolor afterglow application
Authors: Shao Kang , Zhang Hongxi , Ling Qingqing , Xie Wuyan , Gu Danyu , Teng Yuanjie , Yuan Xiufang , Ye Shiyi , Pan Zaifa
Published: June 2023

DF-CDs@SiO2and multicolor CDs@SiO2are applied in advanced information encryption, LEDs, hydrogel-based biosensing, and autofluorescence-free bioimaging.
Master‐slave control strategy of the cascaded multi‐terminal ultra‐high voltage direct current transmission system
Authors: He Sihang , Hao Liangliang , Liu Chang , He Jinghan , Chen Zhengguang
Published: June 2023

In the case of dispersed load consumption, Ultra‐high Voltage Direct Current (UHVDC) system in cascaded connection mode can significantly reduce the cost by building DC lines between different ends, but the communication delay caused by it brings challenges to the original control strategy. Therefore, the control strategy suitable for cascaded multi‐terminal UHVDC (CMT‐UHVDC) system is developed. In this paper, first of all, the operation characteristics, mathematical model, and adaptability of the original control strategy are discussed. Next, an autonomous master‐slave control strategy is proposed to maintain voltage balance without real‐time communication between high‐end and low‐end valves. Finally, based on the planning parameters of an actual project, the electromagnetic transient simulation model of the CMT‐UHVDC transmission system is established. Several working conditions and the practical influence of sampling deviation on the control performance are discussed and analyzed, which verifies the proposed control strategy's effectiveness.
Confronting fuzzy dark matter with the rotation curves of nearby dwarf irregular galaxies
Authors: Bañares-Hernández Andrés , Castillo Andrés , Martin Camalich Jorge , Iorio Giuliano
Published: June 2023

Aims. In this paper, we carry out a phenomenological investigation of the viability of fuzzy dark matter, which is composed of coherent waves of non-interacting ultralight axions with a mass of ma ≈ 10−22 eV. We did so by confronting the predictions of the model, in particular, the formation of a solitonic core at the center of dark matter halos, with a homogeneous and robust sample of high-resolution rotation curves from the LITTLE THINGS in 3D catalog. This comprises a collection of isolated, dark matter-dominated dwarf-irregular galaxies that provides an optimal benchmark for cosmological studies. Our aim is to find evidence of fuzzy dark matter in the observations; alternatively, we seek to set exclusion ranges for its mass.

Methods. We used a statistical framework based on a χ2 analysis of the rotation curves of the LITTLE THINGS in 3D catalog using a fuzzy dark matter profile as the theoretical model. This allows us to extract relevant parameters such as the axion mass and mass of the solitonic core, as well as the mass of the dark matter halo and its concentration parameter. We fit the data using current Markov chain Monte Carlo techniques with a rather loose set of priors, except for the implementation of a core-halo relation predicted by simulations. The results of the fits were then used to perform various diagnostics on the predictions of the model.

Results. Fuzzy dark matter provides an excellent fit to the rotation curves of the LITTLE THINGS in 3D catalog, with axion masses determined from different galaxies clustering around ma ≈ 2 × 10−23 eV. However, we find two major problems from our analysis. First, the data follow scaling relations of the properties of the core, which are not consistent with the predictions of the soliton. This problem is particularly acute in the core radius-mass relation with a tension that (at face value) has a significance of ≳5σ. The second problem is related to the strong suppression of the linear power spectrum that is predicted by fuzzy dark matter for the axion mass preferred by the data. This can be constrained very conservatively by the galaxy counts in our sample, which leads to a tension that exceeds 5σ. We estimate the effects of baryons in our analysis and discuss whether they could alleviate the tensions of the model with observations.
Effects of ABS microplastics on microalgae Chlorella vulgaris and Raphidocelis subcapitata
Authors: Rani-Borges Bárbara , Queiroz Lucas Gonçalves , Ferreira Karen de Souza , Gomes Martins Thaís Fabiane , Vicente Eduardo , Ando Rômulo Augusto , Pompêo Marcelo
Published: June 2023

In recent years, there has been a growing interest in the impacts caused by the presence of microplastics (MP) in aquatic environments. The impacts of microalgae exposure to microplastics are still insufficiently investigated and further studies are needed to understand the possible outcomes. In addition, much of the literature has focused on the study of concentrations above those found naturally in the environment and in less toxic polymer matrices. Acrylonitrile-butadiene-styrene (ABS) plastics have a composition rich in additives and, so far, have been studied superficially. In the present study, two of the most commonly used green microalgae species in toxicity assays, Chlorella vulgaris and Raphidocelis subcapitata, were exposed to different concentrations of primary ABS-MP for a period of 6 days. Here, we observed physiological changes in cell growth and chlorophyll a content induced by the concentration and time of exposure to ABS-MP. The lowest concentration did not prove to be potentially toxic to cells, while the highest concentration was the most toxic. Primary consumers, such as microalgae, are essential for the proper functioning of entire ecosystems. Changes in these communities can lead to permanent damage to the communities of organisms at higher levels, so it is essential that their study be done carefully in the face of threats such as MP.
Optimising generation and energy storage in the transition to net zero power networks
Authors: Grace William
Published: June 2023

As electricity networks plan to achieve net-zero emissions, the role of private behind-the-meter (BTM) generation and storage becomes increasingly important. Two key questions arise for planners: how much BTM will there likely be in the longer term; and what impact will this have on network generation and storage? The combination of high insolation and reducing cost of small-scale solar PV systems in Western Australia has led to a rapid and ongoing take-up of private generation which already supplies around 20% of demand (around one third of houses have rooftop solar), and declining midday network loads, which will likely become negative before 2030 at some times of day and year. However, the market operator has consistently underestimated the rate of private penetration, leading to inadequate planning for the future network. Most published research focusses on network scale renewable generation but neglects the impact of private generation and storage. In contrast, this article presents a model of the integrated system to 2050, projecting the likely scale of BTM generation and identifying the optimal form of network renewable energy and storage to achieve net zero emissions. By 2050 BTM generation will likely supply around 50% of the total annual demand of 54,000 GWh pa. Given the diurnal and seasonal shape of the resulting network load and projected renewable generation costs, onshore wind energy will be the most cost optimal generation source, supplemented by smaller capacity offshore wind, wave and solar PV facilities. Network storage in the form of batteries and pumped hydro will be required, but significant curtailment will still be necessary to optimally match supply with demand. Network generation and storage costs per MWh of network load into the future are likely to be similar to, or lower than existing costs (∼$85/MWh) with the range of technologies considered in this study.
Pathogenesis of anorexia nervosa
Authors: Xintong Xie
Published: June 2023

Anorexia nervosa is a potentially life-threatening psychiatric disorder that threatens the life and health of the patient. Patients are characterized by a very low body mass index, rapid weight loss, an irrational fear of weight gain, and a distorted view of their body image. The disease is closely related to genetic factors, neuroendocrine imbalances, and psychosocial and family factors. In recent years, its morbidity and mortality rates have gradually increased. The causes of death are not only organ failure due to extreme starvation, but also complications due to overmedication and depression and suicide. Currently, nutritional therapy and psychotherapy are the main treatments for the disease. It is mainly found in the adolescent and female population, and the mortality rate of patients is very high. The study of the pathogenesis of anorexia nervosa is of great importance to actively improve the prognosis and save the lives of patients.
The relationship between implicit self-esteem and the level of self-reported Behavioral Activation System (BAS) and Behavioral Inhibition System (BIS)
Authors: Chen Yueping
Published: June 2023

The present study examines the correlation between implicit self-esteem and the level of self-reported Behavioral Activation System (BAS) and Behavioral Inhibition System (BIS). Both name letter measure and implicit association test will be used to measure implicit self-esteem. Also, participants have to complete a self-report questionnaire to get their BAS and BIS score. Then, we sill correlate BAS, BIS with implicit self-esteem. We expect to have strong positive correlation between BAS and implicit self-esteem and strong negative correlation between BIS and implicit self-esteem. So, this study interpretates Implicit self-esteem in the biological view through BAS and BIS. And the finding may help us find a way to improve our implicit self-esteem.
A study of college students’ openness personality and English learning anxiety
Authors: Guo Yuewen , Li Xiaoxiong , Song Su
Published: June 2023

The present situation of college students’ English learning is one of the key research topics. Some studies have found that different personality traits have a great impact on the English learning effect of college students. However, there is still a lack of detailed analysis and summary on the impact of a specific personality on the degree of English learning anxiety. Therefore, the questionnaire that the thesis uses is developed according to the Foreign Language Classroom Anxiety Scale (FLCAS), conducts random surveys for college students from different regions, majors and ages, and makes statistical analysis of the collected data using SPSS to explore the relationship between openness personality traits and the English-learning anxiety level of college students. After discussion and analysis, the results of this study can be divided into two aspects. Firstly, from the anxiety of the subjects, 60% of the 408 subjects have low anxiety about English learning, and their scores were very close to the medium anxiety level (99≤b≤132), while almost only a few respondents were at the high anxiety level. Secondly, there is a linear relationship between openness personality and English learning anxiety. According to the total score, the correlation was 0.338, showing a moderate correlation, and the significance level is 0.01. According to the research results, teachers can improve the teacher-student relationship and relieve students’ anxiety by innovating teaching methods and evaluation systems. However, the results may vary due to confounding factors such as major, gender and age.
How should off-campus training react to the “Double Reduction” policy?
Authors: Yu Shiting
Published: June 2023

After the introduction of the “Double Reduction” policy, off-campus training institutions are under strict supervision. According to the policy details, discipline training institutions confront various problems, such as the closure of listing channels, the substantial reduction of financial income, and the unemployment of the training personnel. By analyzing the current situation of related institutions and their personnel, this study provides meaningful references for discipline training institutions in transformation direction and talent management. Also, it puts forward suggestions for training personnel to change their jobs.
Analysis of the Role of Mother Tongue Transfer in SLA from Cross-cultural Communication
Authors: Liu Yao
Published: June 2023

The mother-tongue transfer has long been an important research topic in the field of second language acquisition. In cross-cultural communication, the mother-tongue transfer can be used not only as a second language learning method but also as an effective means of cross-cultural communication. In the current era of economic globalization and cultural pluralism, it is necessary to pay more attention to the role of mother-tongue transfer in second language acquisition, rather than just treating it as a ‘cultural phenomenon’. This article discusses the advantages and disadvantages of using Chinese as a medium of second language acquisition for learners of English from China, in the form of mother-tongue transfer, from an intercultural perspective. The positive transfer of the mother tongue makes it easier for learners to acquire a second language. For those students who have a weak foundation in English, they are good at using Chinese thought to form sentences. Teachers need not be in denial but should adopt appropriate methods to facilitate positive transfer based on generalizing the similarities and differences between the two languages. Therefore, in the classroom, if teachers can get their students to identify the similarities between English and Chinese, they will be able to promote positive mother-tongue transfer.
Study on the Feasibility and Necessity of Setting Up Student Learning Center in Private Higher Education Institution
Authors: Wang Peibin , Wang Yajin
Published: June 2023

In view of the rapid development of private higher education institution in China and the differences between instructors and students composition and public universities, some students have some problems in learning methods and learning initiative. Setting up special guidance and improving students’ learning and development ability is an important measure to improve the teaching quality of private universities, which is also feasible and necessary. Learning from the successful experience of “Learning Guidance and Development Centers” of universities at domestic and abroad, this paper explores a student learning support system in accordance with the characteristics of private universities, and improves students’ independent learning ability by setting up learning guidance courses, consultation, discussion and peer assistance.
Design of 4P-BL Teaching Mode with Four Integration
Authors: Xiaofang Wang , Tao Guo , Junliang Hou
Published: June 2023

In view of the Ministry of Education “one degree for both sexes” and the new engineering construction objectives, cultivating applied undergraduate talent initiative, initiative and solve practical engineering problems become the focus. Taking the Introduction to Big Data Technology course of Geely University as an example, this paper studies the innovative design of 4P-BL teaching mode based on four-integration and the five-step teaching method.
The Association between Language Ability/Cultural Background and Racial Bias: A Pilot Study
Authors: Zhu Yuxin
Published: June 2023

There has been prejudice and bias towards other races since hundreds of years ago. Even though stereotypical racial bias has decreased or controlled consciously accompanied with education of global equality, a new form of racial differentiation - implicit bias has evolved and attached to our unconscious behaviors. The IAT test and the AMP test are typically used for detecting subtle attitudes and implicit opinions. In this case, a survey adapted from the IAT test is performed using Qualtrics, after which data analysis is conducted through SPSS to prove that multilingualism is less likely to be racially biased compared to monolingualism.
Research on the Internationalization Development and Cooperation Path of Higher Education Between Turkey and China
Authors: Yang Zhen , Tang Yuekun , Xu Yige
Published: June 2023

In recent years, with the irreversible trend of internationalization worldwide, the internationalization of higher education is a key direction of China’s education in the future. Given the current situation of political, economic, and social development in Balkan countries, Turkey strongly desires to develop its internationalization of higher education. This paper will explore the internationalization development status of higher education between Turkey and China, based on which their cooperation path of higher education is summarized.
Research and Practice of Ideological and Political Education in the Course of Data Mining and Analysis
Authors: Yuan Liao
Published: June 2023

The cultivation of moral character and the education of students are the fundamental tasks of higher education. In order to implement this fundamental task, this paper focuses on the course objective of “combining knowledge imparting with value guidance”, and based on the characteristics of the course, explores and investigates the ways and methods of integrating ideological and political education into the teaching of professional courses in the construction and implementation of the “Data Mining and Analysis” course. This paper mainly explores the integration of ideological and political elements into the teaching of the course from four aspects: course objectives, teaching design, teaching process, and teaching evaluation. By integrating ideological and political elements into various aspects of teaching in a planned manner, moral education can penetrate and achieve the goal of “ideological and political education entering the hearts of students and influencing them silently”. This research has a certain universality and can provide useful reference for the practical teaching of ideological and political education in relevant colleges and universities.
Research on the Teaching Path of Integrating Excellent Traditional Chinese Culture into the Course of “Spoken Language for Preschool Teachers”
Authors: hui Liu , YiBei Shi
Published: June 2023

Teaching in universities should not only meet the development needs of students’ professional skills, but also focus on imparting classroom ideological and political elements. As the core course of preschool education, “ Spoken Language for Preschool Teachers “ aims to deeply explore the connotation of traditional Chinese culture, strengthen the power, consolidate the platform, and innovate the mode of education, lead students to inherit the Chinese spirit. On the basis of analyzing the characteristics of the course “ Spoken Language for Preschool Teachers”, this article proposes specific construction plans and implementation strategies.
Research on the ways in which law changes cognition in cognitive offensive and defensive wars
Authors: Ying Li , Enzhi Yu
Published: June 2023

With the outbreak of the Russian-Ukrainian conflict, the focus of all countries in the world on cognitive domain operations has reached a new height, and some people call it “the last frontier of military science.” Starting from the basic theory, this paper expounds the theoretical basis why cognitive attack and defense can become the theoretical basis of war. Finally, combined with the new characteristics of cognitive offensive and defensive battlefields, this paper attempts to summarize the way to combine legitimacy and other cognitive change elements for cognitive offensive and defensive to win future wars from a microscopic perspective.
Research on Ways of Strengthening the Rule of Law Awareness for Students in Higher Vocational Colleges in the New Era
Authors: Luan Luan
Published: June 2023

Strengthening the rule of law awareness for students in higher vocational colleges in the new era is of great significance for the career development of students, the education of vocational colleges, and the rule of law of the country. However, higher vocational students lack legal knowledge and the ability to solve problems according to the law. As such, higher vocational students, higher vocational colleges, and families should give full play to their respective roles and explore various ways to improve the rule of law awareness for students in higher vocational colleges.
The Research of University Librarians Participating in the Guidance of University Students’ Discipline Competition
Authors: Yin Honglei , Lv Zhengfang
Published: June 2023

The discipline competition of college students is an important part of innovation and entrepreneurship education, and is increasingly valued. As an important teaching auxiliary department, university libraries have a large number of library resources and a sufficient number of teachers, and should actively participate in the guidance of discipline competitions. To this end, we should determine the scope of the subject competition, establish a team of instructors, choose the suitable students participating in the competition, optimize the layout of the library to facilitate students to participate in the competition, strengthen the cooperation between schools and enterprises, and establish the database of the subject competition of excellent entries in the school.
The Development of Loose-Leaf Teaching Materials Based on the Concept of Outcome-Based Teaching Model and Its Effectiveness
Authors: Li Ling
Published: June 2023

At present, loose-leaf teaching materials are attracting more and more attention in higher vocational institutions and have become a hot topic now. However, since the development of loose-leaf teaching materials is still in its beginning and exploratory stage, the examples of loose-leaf teaching materials for specialized courses are very hard to find. In fact, there is little research and application of how teaching objectives, content structure, teaching methods and teaching effectiveness reflect the original intention of loose-leaf teaching materials, especially there is little empirical evidence and reporting on teaching effectiveness. In this paper, we adopt the concept of outcome-based teaching model and take “Check-in” in Professional English for Hotel Staff course as an example to demonstrate the development and design of loose-leaf teaching materials and their features of career guidance, brevity and clarity, simplicity and practicality, real time and flexibility. By comparing the fourth semester exam results of 125 students majoring in hotel management from the class of 2013 to the class of 2016, who used traditional hotel English textbook，with the fourth semester exam results of 112 students from the class of 2017 to the class of 2020, who used loose-leaf teaching materials of hotel English in a higher vocational college, the advantages of the “4Es” embodied in loose-leaf teaching materials, namely, easy to teach, easy to learn, easy to understand and easy to use, and their effectiveness are revealed. According to the current study and preliminary teaching results, the development of the loose-leaf textbook based on the concept of outcome-based teaching model has been effective.
Mobilidade e resistência muscular lombopélvica e associação com dor musculoesquelética em bailarinas
Authors: Padilha Vitória Hamdan , Lara Simone , Graup Susane , Teixeira Lilian Pinto , Silva Loreanne dos Santos , Maciel Eduardo Timm
Published: June 2023

Objetivo Analisar a mobilidade e a resistência muscular lombopélvica e mobilidade de tornozelo, assim como identificar os fatores associados com dor musculoesquelética em bailarinas jovens.

Métodos Trata-se de um estudo quantitativo, descritivo e transversal que avaliou 14 bailarinas de 12 a 16 anos. Os seguintes instrumentos foram aplicados: a) Questionário Nórdico de Sintomas Osteomusculares (QNSO) para avaliação da dor musculoesquelética; b) leg lateral reach test, lumbar lock e rotation test (avaliação da mobilidade de tronco) e lunge test (avaliação da mobilidade de tornozelo); c) ponte frontal, extensores lombares e flexores lombares para avaliação da resistência do complexo lombopélvico.

Resultados A dor lombar e em membros inferiores, especialmente no joelho (57,1%), foram as principais queixas relatadas pelas bailarinas no presente estudo. As bailarinas avaliadas com dor lombar apresentavam significativamente menor mobilidade lombar (p = 0,05) e menor mobilidade de tornozelo em ambos os lados (p ≤ 0,05). Entre as que apresentavam dores nos joelhos, a resistência muscular de extensores de tronco foi significativamente menor (p = 0,05).

Conclusões O presente estudo encontrou associações importantes entre a função do complexo lombopélvico e sintomas musculoesqueléticos e apoia a construção de estratégias preventivas neste contexto.
Polimorfismos genéticos no gene COL1A2 e o risco de tendinopatia: Estudo de caso-controle
Authors: Lopes Lucas Rafael , Guimarães João Antônio Matheus , Amaral Marcus Vinicius Galvão , Pereira Camili Gomes , Wainchtock Victor Soares , Goes Rodrigo Araujo , Miranda Vitor Almeida Ribeiro de , Perini Jamila Alessandra
Published: June 2023

Objetivo Avaliar a influência de polimorfismos nos genes que codificam o colágeno tipo I e a suscetibilidade genética da tendinopatia.

Metodologia Estudo caso-controle envolvendo 242 atletas brasileiros de diferentes modalidades esportivas (55 casos de tendinopatia e 187 controles). Os polimorfismos COL1A1 (rs1107946) e COL1A2 (rs412777, rs42524 e rs2621215) foram analisados pelo sistema TaqMan. As razões de chance (OR) com seus intervalos de confiança (IC) de 95% foram calculadas usando um modelo de regressão logística não-condicional.

Resultados A média de idade foi de 24,0 ± 5,6 anos e 65,3% eram homens. Dos 55 casos de tendinopatia, 25,4% apresentaram mais de um tendão acometido, sendo os mais frequentes o patelar (56,3%), o manguito rotador (30,9%) e o do cotovelo ou flexores das mãos (30,9%). A idade e o tempo de prática esportiva foram associados a uma maior chance de apresentar tendinopatia (5 e 8 vezes, respectivamente). A frequência dos alelos variantes nos controles e casos, respectivamente, foi: COL1A1 rs1107946 24,0 e 29,6%; COL1A2 rs412777 36,1 e 27,8%; rs42524 17,5 e 25,9%; e rs2621215 21,3 e 27,8%. Após ajuste pelos fatores de confundimento (idade e anos de práticas esportiva), os polimorfismos COL1A2 rs42524 e rs2621215 foram associados a um risco aumentado de tendinopatia (OR = 5,5; IC95% = 1,2–24,6 e OR = 3,9; IC95% = 1,1–13,5, respectivamente). O haplótipo COL1A2
CGT foi associado a um baixo risco para desenvolvimento da doença (OR = 0,5; IC95% = 0,3–0,9).

Conclusão A idade (≥ 25 anos), o tempo de prática esportiva (≥ 6 anos) e polimorfismos no gene COL1A2 aumentaram o risco de desenvolvimento da tendinopatia.
Análise de propriocepção por estabilometria após a reconstrução do ligamento cruzado anterior: Um estudo prospectivo e longitudinal
Authors: Al-Dadah Oday , Shepstone Lee , Donell Simon T.
Published: June 2023

Objetivo Os métodos comumente usados para medir a propriocepção resultaram em relatos conflitantes sobre a propriocepção do joelho com ruptura do ligamento cruzado anterior (LCA) e a influência da reconstrução do LCA.

Métodos A propriocepção de 100 indivíduos (50 pacientes com ruptura unilateral do LCA confirmada à radiologia e artroscopia e 50 controles normais) foi avaliada por estabilometria postural dinâmica em apoio unipodal. A lassidão ligamentar do joelho instrumentado e suas pontuações de desfechos também foram medidas. Dos 50 pacientes do grupo LCA, 34 foram submetidos à reconstrução e reavaliados no período pós-operatório.

Resultados O grupo LCA apresentou deficiência proprioceptiva significativa em relação ao joelho contralateral (p < 0,001) e ao grupo controle (p = 0,01). A propriocepção do joelho melhorou de maneira significativa após a reconstrução do LCA em relação aos achados pré-operatórios (p = 0,003). Não houve correlação entre as medidas de lassidão ligamentar e as pontuações de desfechos. Além disso, observamos uma correlação significativa entre as pontuações de desfechos e as medidas de propriocepção antes da cirurgia. Essa correlação não foi detectada no período pós-operatório. O teste pré-operatório de propriocepção teve correlação significativa (r = 0,46) com a propriocepção pós-operatória (p = 0,006).

Conclusão Os pacientes com ruptura do LCA apresentaram déficit proprioceptivo que melhorou após a reconstrução ligamentar. As pontuações de desfecho do joelho tiveram melhor correlação à propriocepção do que a lassidão ligamentar. A propriocepção pode ser uma medida objetiva superior à lassidão ligamentar na quantificação de déficits funcionais e desfechos do joelho em pacientes com ruptura do LCA.

Nível de Evidência III Estudo Terapêutico; Estudo de Caso-Controle Longitudinal Prospectivo.
Osteointegração e sucesso em revisão acetabular de artroplastia total de quadril com enxerto estrutural homólogo: seguimento médio de 9,6 anos
Authors: Roos Bruno Dutra , Roos Milton Valdomiro , Camisa Antero , Lima Ezequiel Moreno Ungaretti , Betto Maurício Domingos , Dubiela Rafaela Scuzziato
Published: June 2023

Objetivo Avaliar os resultados clínicos, radiográficos e a sobrevida da cirurgia de revisão acetabular de artroplastia total de quadril com implante cimentado sem uso de anel de reforço, associado à enxertia óssea homóloga estrutural.

Métodos Um total de 40 pacientes (44 quadris) operados de 1995 a 2015 foram analisados retrospectivamente. As radiografias foram avaliadas de acordo com a classificação do defeito ósseo acetabular, o formato do enxerto e à presença de osteointegração. Foram considerados casos de insucesso a migração do implante > 5mm em qualquer direção e/ou a progressão de linhas de radioluscência em torno do componente acetabular > 2mm. Verificamos a associação dos achados radiográficos com os casos de falha utilizando testes estatísticos e analisamos a sobrevida utilizando a curva de Kaplan-Meier.

Resultados Dos 44 quadris, 45,5% dos defeitos acetabulares eram Paprosky tipo 3A e 50%, 3B. Em 65% dos quadris, a configuração do enxerto foi classificada como tipo 1 de Prieto e em 31% como tipo 2. Não foi observada evidência radiográfica de osteointegração em 13,6% dos casos. Observamos 9 (20,5%) falhas de reconstrução. Foi observada correlação entre falha da reconstrução com a ausência de sinais radiográficos de osteointegração do enxerto.

Conclusão Observamos bons resultados clínicos e radiográficos, com sobrevida de 79,54% em seguimento médio de 9,65 anos. Também houve associação entre ausência de sinais radiográficos de osteointegração do enxerto estrutural e falha nesta série de pacientes com grandes defeitos ósseos. As falhas não se correlacionaram com a severidade do defeito ósseo acetabular, espessura ou configuração do enxerto.
Circumbilical Access for Ventriculoperitoneal Bypass Insertion in Adults
Authors: Silva Vithor Ely Bortolin da , Rodrigues José Carlos
Published: June 2023

Introduction The use of a minilaparotomy for catheter implantation can bring important complications such as adhesions, intestinal lesions, incisional hernias and postoperative pain. In neurosurgery, the umbilical access, currently widely used by surgeons of different specialties mainly for its aesthetic results, is still restricted by the unfamiliarity of the access.

Material and Method During the period between 2019 and 2020, a total of 12 patients who required ventricular bypass were selected, using circumbilical access for insertion of the peritoneal catheter and followed up for 12 months to analyze possible complications.

Description of the Technique The surgeon responsible for the abdomen performs an umbilical incision bordering the upper edge of the upper ring, avoiding the mamelon, quickly finding the linea alba under the umbilical plane, which after dissection allows reaching the peritoneum, without breaking the rectus muscles. The peritoneum can then be opened under visual control.

Results All patients presented resolution of hydrocephalus with good aesthetic results and without complications.

Discussion The aesthetic result of the transumbilical procedure was the stimulus for the development of the technique that proved to be easy, safe, cheap, and aesthetic. Initially, the ease of access to the peritoneal cavity is clear, in addition to avoiding manipulation of the rectus abdominis muscle, which improves postoperative pain.

Conclusion The circumbilical access for the implantation of a ventriculoperitoneal shunt is safe, effective and has a better aesthetic result for adult patients and should be part of the operative arsenal of neurosurgeons.
Zhang Zhongjing Cultural Brand Construction from the Perspective of Traditional Chinese Medicine Culture and Wellness Tourism
Authors: Xu Erping , Liu Baoguang , Bai Ming , Liu Yalin , Li Yucheng , Wang Baoying , Chen Yiheng , Xie Miao , Dong Ying
Published: June 2023

Nowadays, traditional Chinese medicine (TCM) culture and wellness tourism are developing toward integration with an inherent and inevitable basis. A new business mode of TCM wellness tourism bred has emerged, injecting new vitality into the development of TCM culture and innovation of tourism. As the cultural representative of TCM industry, Zhang Zhongjing culture should seize the opportunity to make a breakthrough in its brand construction with the help of wellness tourism. The main construction strategies include actively launching books or films and television dramas based on the deeds of Zhang Zhongjing and other famous TCM doctors, turning herbs cultivation bases into special tourism and sightseeing parks, establishing research and dissemination bases of TCM culture, and building TCM wellness tourism bases that integrate learning, rehabilitation, and tourism, using information technology and cultural media platforms to introduce Zhang Zhongjing culture to the world.
Association between Peripartum Mean Arterial Pressure and Postpartum Readmission for Preeclampsia with Severe Features
Authors: Lin Bing-Xue , Smith Maria , Sutter Megan , Penfield Christina A. , Proudfit Christine
Published: June 2023

Objective This study aimed to evaluate the relationship between peripartum mean arterial pressure (MAP) and postpartum readmission for preeclampsia with severe features.

Study Design This is a retrospective case–control study comparing adult parturients readmitted for preeclampsia with severe features to matched nonreadmitted controls. Our primary objective was to evaluate the association between MAP at three time points during the index hospitalization (admission, 24-hour postpartum, and discharge) and readmission risk. We also evaluated readmission risk by age, race, body mass index, and comorbidities. Our secondary aim was to establish MAP thresholds to identify the population at highest risk of readmission. Multivariate logistic regression and chi-squared tests were used to determine the adjusted odds of readmission based on MAP. Receiver operating characteristic analyses were performed to evaluate risk of readmission relative to MAP; optimal MAP thresholds were established to identify those at highest risk of readmission. Pairwise comparisons were made between subgroups after stratifying for history of hypertension, with a focus on readmitted patients with new-onset postpartum preeclampsia.

Results A total of 348 subjects met inclusion criteria, including 174 controls and 174 cases. We found that elevated MAP at both admission (adjusted odds ratio [OR]: 1.37 per 10 mm Hg, p < 0.0001) and 24-hour postpartum (adjusted OR: 1.61 per 10 mm Hg, p = 0.0018) were associated with increased risk of readmission. African American race and hypertensive disorder of pregnancy were independently associated with increased risk of readmission. Subjects with MAP > 99.5 mm Hg at admission or >91.5 mm Hg at 24-hour postpartum had a risk of at least 46% of requiring postpartum readmission for preeclampsia with severe features.

Conclusion Admission and 24-hour postpartum MAP correlate with risk of postpartum readmission for preeclampsia with severe features. Evaluating MAP at these time points may be useful for identifying women at higher risk for postpartum readmission. These women may otherwise be missed based on standard clinical approaches and may benefit from heightened surveillance.

Key Points