bluuebunny/crossref_metadata_2025 huggingface dataset:
A Rare Presentation of Transverse Testicular Ectopia and Role of Laparoscopy
Authors: Piplani Rajat
Published: December 2022

Transverse testicular ectopia (TTE) is an uncommon congenital anomaly, in which both the gonads migrate towards the same hemi-scrotum. We report a rare case of TTE discovered coincidentally during surgery in a 1-year-old boy who presented with bilateral undescended testis and right inguinoscrotal swelling. The use of laparoscopy during evaluation for impalpable testis can aid in the diagnosis of TTE, before inguinal exploration. Findings such as the vascular supply and vas deferens of the crossed testis and the identification of Müllerian structures can be confirmed by laparoscopy. Diagnostic laparoscopy was suggestive of both the testes entering in the right-sided open deep inguinal ring, while left-sided deep inguinal ring was found to be closed. There was no evidence of persistent Müllerian structures. On exploration, both testes were present in the right inguinal region. A bilateral trans-septal orchidopexy along with right herniotomy was performed.
Autodelineation of organ at risk in head and neck cancer radiotherapy using artificial intelligence
Authors: Bilimagga Ramesh S. , Anchineyan Pichandi , nmugam Murli Shivasha , Thalluri Seshashayi , Goud P. Sudheer Kumar
Published: December 2022

Aim:

The aim of this study is to check the practical feasibility of artificial intelligence for day-to-day operations and how it generalizes when the data have considerable interobserver variability.

Background:

Automated delineation of organ at risk (OAR) using a deep learning model is reasonably accurate. This will considerably reduce the medical professional time in manually contouring the OAR and also reduce the interobserver variation among radiation oncologists. It allows for quick radiation planning which helps in adaptive radiotherapy planning.

Materials and Methods:

Head and neck (HN) computed tomography (CT) scan data of 113 patients were used in this study. CT scan was done as per the institute protocol. Each patient had about 100–300 slices in Dicom format. A total number of 19,240 images were used as the data set. The OARs were delineated by the radiation oncologist in the contouring system. Of the 113 patient records, 13 records were kept aside as test dataset and the remaining 100 records were used for training the UNet 2D model. The study was performed on the spinal cord and left and right parotids as OARs on HN CT images. The model performance was quantified using the Dice similarity coefficient (DSC) score.

Results:

The trained model is used to predict three OARs, spinal cord and left and right parotids. The DSC score of 84% and above could be achieved using the UNet 2D Convolutional Neural Network.

Conclusion:

This study showed that the accuracy of predicted organs was within acceptable DSC scores, even when the underlying dataset has significant interobserver variability.
Prevalence of oral potentially malignant disorders (OPMD) in adults of Western Maharashtra, India
Authors: Shivakumar K. M. , Raje Vaishali , Kadashetti Vidya
Published: December 2022

Background:

Oral cavity cancer is estimated to be the third most common malignancy after cancer of cervix and stomach in developing countries.

Objectives:

The objective of this study is to investigate the relationship between smoking, alcoholic consumption, betel quid chewing, and OPMD in a prospective manner.

Materials and Methods:

A descriptive, cross-sectional study was conducted among 35–55-year-old adults of Western Maharashtra, India. Oral cavity examination as recommended by the American Dental Association specification was followed. Data recorded were transferred from precoded survey pro forma to the computer. The prevalence of OPMD was assessed by determining the percentage of the study population affected. Analysis was done to find out the risk of oral premalignant disorders. The Chi-square (x
2) test and adjusted odds ratio (ORs) with 95% confidence interval (CI) were calculated. The Statistical Package for the Social Sciences (SPSS) software version 21.0 was used for the statistical analysis and significance level was set at P < 0.05.

Results:

Odds of having OPMD are five times higher for those who smoke (OR = 5.78; 95% CI, [6.18, 7.82]) as compared to those who do not. The odds of suffering from OPMD are about five times higher among those who chew as compared to those who do not (OR = 4.98; 95%CI, [2.91, 7.28]). The mean frequency of tobacco chewing per day and duration in years in participants with OPMDs was significantly higher as compared with normal oral mucosa (P < 0.05 and P < 0.05), respectively, in the use of different tobacco forms.

Conclusion:

These findings can be used to design case control or cohort studies to further understand the relation between habits and OPMD.
An integrative analysis to enumerate candidate genes for clinical use in oral cancer
Authors: Thakore Vaidehi P. , Patel Kinjal D. , Bhadresha Kinjal P. , Patel Prabhudas S. , Jain Nayan K.
Published: December 2022

Background:

Oral cancer (OC) is the most pernicious sub-site of head and neck tumours with poor prognostic value that is largely ascribed to the lack of ideal biomarkers and therapeutic targets. This fact highlights an urgent need to identify biomarkers that can further aid in OC management.

Aim:

The aim of this study was to identify a gene panel with a maximum clinical utility for OC.

Materials and Methods:

Eight eligible datasets were downloaded from the Gene Expression Omnibus Database, containing 320OC samples and 173 normal samples. The data were processed by GeneSpring software to reveal differentially expressed genes between OC tissues and normal tissues in eight individual experiments. Functional enrichment and network analysis were performed using PANTHER and STRING databases for concordant genes (fold change >10; P ≤ 0.05). The selected genes were cross-validated in the cancer genome atlas (TCGA), Oncomine, and KaplanMeier (KM) plotter databases.

Results:

Totally, 65 concordant genes were identified, including 37 up-regulated genes and 28 down-regulated genes. A 13-gene panel CXCL8, CXCL10, FN1, GBP1, IFIT3, ISG15, MMP1, MMP3, MMP10, OASL, SERPINE1, SPP1, and PLAU was elected from the lists of functionally enriched genes, hub genes, and genes that showed high alterations for mutation, copy number variation, and mRNA expression status in 'Head and Neck Squamous Cell Carcinoma patients (n = 279; TCGA, Nature 2015)'. Further, validation in Oncomine database demonstrated significant over-expression of all elected genes in OC patients across multiple datasets. In addition, out of 13, six genes (CXCL8, CXCL10, FN1, PLAU, SERPINE1, and SPP1) showed significant association with the prognosis of Head and Neck cancer patients (n = 500) in the KM plotter database.

Conclusions:

Using an integrative analysis, our study investigated and validated a 13-gene panel for OC which can be used to improve current diagnostic, prognostic, and treatment approaches.
Perioperative antimicrobial prophylaxis in clean-contaminated head and neck squamous cell cancer surgeries
Authors: Kohli Pavneet , Penumadu Prasanth , Shukkur Naveeth , Sivasanker M , Balasubramanian Arumugam , Ganapathy Sachit
Published: December 2022

Introduction:

Judicious use of antibiotics and stringent adherence to practice guidelines is the need of the hour as antibiotic resistance is a rampant problem. Despite several reports in the literature describing the optimal duration of antibiotics, there is no consensus. A “one for all” protocol may be impractical and hence the guidelines need to be tweaked to take into consideration local factors. We designed a protocol for prophylactic antibiotics in clean-contaminated head and neck cancer squamous cell carcinoma (HNSCC) surgeries to prevent unchecked abuse and evaluated its feasibility.

Materials and Methods:

Two hundred consecutive patients who underwent a clean-contaminated surgery for HNSCC between January 2017 and December 2019 were included. Single-dose intravenous amoxicillin-clavulanate at induction followed by three doses of amoxicillin-clavulanate, metronidazole, and amikacin in the postoperative period was used. Adherence to the antibiotic protocol was assessed from a prospectively maintained database.

Results:

The mean age was 55.99 ± 11.71 years. The protocol was effective in 70% of the patients with an acceptable surgical site infection (SSI) rate of 12%. Flap-related complications (9.5%) and oro-cutaneous fistula (5%) were common causes of prolonged antibiotics. On univariate analysis, blood transfusion (P = .014), clinical stage at presentation (P = .028), patients undergoing reconstruction (P = .001), longer operative time (P = .009), and pathological T stage (P = 0.03) were at higher chance of deviating from the protocol. On multivariate analysis, age more than 50 years (OR: 2.14, 95% CI: (1.01, 4.52); P value = 0.047) and reconstruction (OR: 3.36, 95% CI: (1.21, 9.32); P value = 0.020) were found to be significant.

Conclusions:

A three-dose perioperative antibiotic prophylaxis in clean-contaminated HNSCC surgeries is feasible. Similar protocols should be developed and validated at other major centers to limit the unnecessary use of antibiotics and prevent the emergence of antibiotic resistance.
Outcomes of feeding jejunostomy after pancreaticoduodenectomy
Authors: Yamamoto Naoto , Aoyama Toru , Murakawa Masaaki , Kamiya Mariko , Shiozawa Manabu , Rino Yasushi , Masuda Munetaka , Morinaga Soichiro
Published: December 2022

Aims:

Feeding jejunostomy tube (FJT) is one option for enteral nutrition after pancreaticoduodenectomy (PD); however, controversy regarding its clinical outcome(s) persists. The aim of the present study was to determine the safety and efficacy of FJT management.

Materials and Methods:

Data from 156 consecutive patients, who underwent PD between January 2015 and December 2017, were retrospectively reviewed. Safety was assessed according to postoperative and tube-related complications. Nutritional efficacy was evaluated based on improvement in serum albumin levels.

Results:

Thirty-day morbidity and mortality rates were 61.0% (n = 95) and 1.9% (n = 3), respectively. The rates of clinically relevant postoperative pancreatic fistula and delayed gastric emptying were 30.8% and 9.0%, respectively. In total, nine (5.8%) patients experienced complications directly related to FJT. Eight patients experienced surgical site infection adjacent to the catheter/skin interface. Although all required catheter removal at the bedside or in the office, none required reoperation. The improvement in serum albumin level 1 month after PD was 40.7% compared with 1 week after PD.

Conclusion:

FJT was useful in improving nutritional intake and status. Although FJT was associated with minor self-limiting complications, they could be managed by simple bedside or office treatment. As such, results of this study support the safety and efficacy of the FJT protocol used in the authors' department for nutritional management.
Pretreatment nutritional status, HPV infection, and tumor infiltrating lymphocyte as prognostic predictors in patients with head and neck squamous cell carcinoma after chemotherapy
Authors: Sutandyo Noorwati , Brahma Bayu , Ifandriani Rizky
Published: December 2022

Background:

The survival rate in head and neck cancer varies among the subtypes, yet, the factors associated with survival between studies are still conflicting. This study aimed to investigate the association between pretreatment nutritional status, human papilloma virus (HPV) infection, tumor infiltrating lymphocyte (TIL), and treatment response after chemotherapy in patients with head and neck squamous cell carcinoma (HNSCC) in Indonesia. Further, factors associated with overall survival were also assessed.

Methods:

This was a retrospective cohort study. Data were collected between January 2015 and January 2018. A total of 30 patients with histopathologically proven squamous cell carcinoma head and neck cancer who had received at least three cycles of chemotherapy were included. Nutritional status was assessed using body mass index (BMI).

Results:

The mean BMI was 21.8 kg/m2 (Standard Deviation 3.98). The underweight patients had a higher risk of progressive disease (OR = 12.1, 95% CI = 1.1-135.6, P = 0.04) compared to patients with higher BMI. Neither HPV infection nor TIL was associated with treatment response and overall survival (P > 0.05). The median survival for the underweight patients was 9 months (95% CI = 3.00-15.00), whereas the median survival for normal and obese patients was 14 months (95% CI = 9.33-18.67).

Conclusion:

Underweight is associated with a significantly higher risk of progressive disease and tends to have shorter overall survival in patients with HNSCC. Yet, neither HPV infection nor TIL was associated with treatment response and overall survival.
Clinicopathologic significance of human epidermal growth factor receptor 2 expression and gene amplification in gastric carcinoma
Authors: Senel Fatma
Published: December 2022

Aim:

This study is aimed at determining the human epidermal growth factor receptor-2 (HER-2) gene status in gastric cancers using immunohistochemistry (IHC) and silver DNA in situ hybridization (SISH) technique and investigating the relationship between HER-2 status and clinicopathological variables.

Materials and Methods:

We examined 104 gastric carcinoma cases with gastrectomy specimens. The age, sex, histopathological tumor type, tumor differentiation, tumor localization, tumor size, invasion depth, lymph node metastasis status, HER-2 IHC evaluation results, and SISH evaluation results of the cases were recorded.

Results:

In the present study, the SISH-confirmed HER-2 positivity rate (SISH amplification) is 14.4%. A statistically significant relationship was found between HER-2 status and tumor invasion depth (P = 0.03). It was observed that as the depth of invasion increased, HER-2 positivity decreased. No statistically significant relationship was found between HER-2 status and sex, age, tumor size, differentiation, histopathological classification, lymph node metastasis, and tumor localization (P > 0.05). The rate of HER-2 2+ cases was found to be high.

Conclusion:

HER-2 status is negatively correlated with the depth of invasion in gastric cancers, and HER-2 positivity increases as the depth of invasion decreases. HER-2 may be early molecular evidence in oncogenesis. Immunohistochemically, HER-2 2+ cases should be confirmed by the in situ hybridization (ISH) technique.
Dermatofibrosarcoma protuberans
Authors: Dahiya Sakshi , Tomar Reena , Ahuja Manisha , Mallya Varuna , Mandal Shramana , Khurana Nita , Rathi Arun Kumar
Published: December 2022

Introduction:

Dermatofibrosarcoma protuberans (DFSP) is an uncommon skin tumor with a low-to-intermediate grade of malignancy, characterized by progressive growth and a propensity for local recurrence. In this series, we are analyzing the clinicopathological spectrum of DFSP cases.

Materials and Methods:

A retrospective study of 12 patients with DFSP who were diagnosed at our institute over the last 2 years (2018–2020) was performed.

Results:

The clinicopathological spectrum and immunohistochemistry of DFSP cases were studied with one case with lymph node metastasis, which is a rare entity, and two cases of the fibrosarcomatous DFSP were also diagnosed and warrant a special mention.

Conclusion:

Pathologists should be aware of metastasis and unusual variants while reporting dermatofibrosarcoma.
Personalized dendritic cell vaccination in cancer therapy: An evidence-based research study
Authors: Hatzidaki Eleana , Papasotiriou Ioannis
Published: December 2022

Background:

Although chemotherapy is considered to be the golden standard, it does not come without a price. Toxicities and resistance are frequently limiting its effectiveness. Immunotherapy has emerged as a safer therapeutic alternative but still has a long way until it has proven to be of equal efficacy. A type of immunotherapy is dendritic cell (DC) vaccination.

Aims and Objectives:

We have developed a novel platform for the generation of autologous DCs that have been activated against peptides that are personalized for each patient individually. The aim of the study was to clinically evaluate this platform.

Materials and Methods:

Our platform and our algorithm for the determination of the immunogenic peptides has been tested. DC generation was verified both morphologically and by CD80/86 expression. Peptide antigenicity was determined using a number of T-cell epitope prediction algorithms. Response to therapy was evaluated using response evaluation criteria in solid tumors (RECIST) criteria by the doctors involved. Immune status was also evaluated before and after DC vaccination and correlated with circulated tumor cell count.

Results:

It was found that DC vaccine increased immune activation while correlated with decreased circulating tumor cell counts. Clinical evaluation by the determination of immune markers may be a superior tool than using RECIST criteria.

Conclusion:

Dendritic cell therapies could prove to be a valuable tool in cancer treatment.
A prospective clinical study to assess primary hypothyroidism in head and neck cancer patients treated with external beam radiotherapy
Authors: Shewalkar Balaji K. , Balachandran Roopa , Pant Punita , Patel Jitendra
Published: December 2022

ABSTRACTS

Purpose:

Head and neck cancers are treated by multimodality methods like surgery, radiotherapy, and chemotherapy. Hypothyroidism is one of the late side effects of radiation to the neck. The main aim of the study was to assess the incidence of primary hypothyroidism in patients with head and neck cancers, who received therapeutic external beam radiation; to evaluate the time duration and the total dose of radiation for the development of hypothyroidism.

Materials and Methods:

A prospective observational study was conducted in our institute on 200 patients from December 2018 to April 2020 with head and neck cancers, which were proven histopathologically. They received external beam radiation using Cobalt 60 or Linear accelerator. A thyroid function test was done in patients after 3 months and 6 months of completion of radiotherapy.

Results:

The incidence of hypothyroidism was 8% after 3 months (P value = 0.0088) post radiation and increased to 14% after 6 months (P value = 0.0024). Of the patients who developed hypothyroidism, a maximum number of cases (24; 86%) were given 60 Gy radiation dose, three (10%) were given 40–59 Gy, and one (3%) was given up to 40 Gy as the mean dose of radiation to the lower neck. A P value of 0.750 was not significant; hence, a dose of radiation was not a significant factor. The patients treated with the two-dimensional (2-D) technique (50%) had a higher incidence of hypothyroidism than the patients treated with three-dimensional conformal radiation therapy (3D-CRT) (14.8%) and intensity-modulated radiation therapy (IMRT) (9%). The use of concurrent cisplatin was not a significant factor for hypothyroidism (P value = 1).

Conclusion:

Thyroid function test should be done in patients who received therapeutic external beam radiation to the neck at baseline and periodically. The early detection and treatment can prevent complications of long-term thyroid hypofunction like hypercholesterolemia, cardiovascular side effects, menstrual irregularities, infertility, peripheral neuropathy, depression, and myxoedema.
Definitive chemoradiation in nonmetastatic squamous cell carcinoma anal canal
Authors: Kumar Viney , Bansal Saurabh , Badola Amit , Nautiyal Vipul , Gupta Meenu , Ahmad Mushtaq , Saini Sunil
Published: December 2022

Purpose:

The purpose of the study was to analyze the survival outcomes and toxicities in squamous cell carcinoma anal canal treated with definitive chemoradiotherapy.

Materials and Methods:

Retrospective analysis of 51 patients with squamous cell carcinoma anal canal treated with chemoradiotherapy was done. Data were collected and analyzed for disease-free survival (DFS), colostomy-free survival (CFS), overall survival (OS), and acute/late toxicities.

Results:

Out of total 51 patients, only 44 patients had a follow-up of more than 36 months and were analyzed. After a median follow-up of 46 months (range 10–68 months), the 3-year DFS was 73.9%. Three patients developed locoregional recurrence, while one patient developed distant metastasis. At 3-year OS rate was 77%. Out of 44 patients, six patients lost to follow–up, while two patients died due to progressive disease and two due to noncancer causes. 3-year CFS rate was 59%. Most common grade >3 acute toxicities were skin reactions in nine (18%), followed by hematological in eight (16%) patients.

Conclusion:

Definitive chemoradiotherapy in anal canal results in good oncological outcomes with sphincter preservation. No severe treatment-related toxicities were observed.
A Case of Bipolar Disorder due to Multiple Sclerosis with Episodes of Mania
Authors: Xin Gan Ning , Yee Kenny Ong Kheng , Kiat Ang Jin
Published: December 2022

Bipolar and related disorders are common and disabling psychiatric conditions. Bipolar illness with manic manifestations is commonly found in patients suffering from multiple sclerosis (MS). This case report highlights the development of manic symptoms in a patient with MS and the association between them. We report a 16-year-old female patient with relapsing–remitting MS (aggressive disease) with 8 relapses in the first 2 years of illness who developed recurrent episodes of mania during each relapse of MS. Neuroimaging showed new left frontal plaques in addition to frontal lobe deficit found during neuropsychiatric assessment. She was stabilized with rituximab therapy 6 monthly and risperidone 2 mg daily. There is a high prevalence of mood disturbances in patients with MS, thus increases their morbidity. A comprehensive psychiatric assessment is important to ascertain the psychiatric diagnosis (primary, secondary, or idiopathic), and prompt treatment is needed. To date, there is no specific treatment guideline for mood disorder secondary to MS available. Future research and clinical practice guidelines are needed in this area.
Disturbed eating attitudes among male and female undergraduate medical students at a tertiary center, Telangana
Authors: Sohel Mohammad , Reddy Mallepalli Pramod Kumar , Chandra Nikitha Chowdary
Published: December 2022

Introduction:

Eating attitude can simply be defined as the beliefs, thoughts, feelings, and behaviors toward food, whereas disturbed eating approach is defined as an eating behavior that does not permit the diagnosis of an eating disorder. Problematic eating attempts in both male and female populations have now become a global debate. In research, body mass and weight concerns, dissatisfaction with one's current appearance, depression anxiety, stress, and social pressures have all been found as common facilitating variables of problematic eating habits among college students.

Aims and Objectives:

The aim of this study is to assess the disturbed eating attitude among male and female medical undergraduates from a tertiary medical center, Telangana.

Materials and Methods:

This was a questionnaire-based, cross-sectional study. The duration of the study was from January to June 2021. Eating Attitude Test based on 26 items (EAT-26) was adapted to Google Forms and circulated among undergraduate medical students from a tertiary hospital center, Telangana.

Results:

Male and female medical students were compared in terms of their disturbed eating attitudes in this study. The EAT was used to determine whether or not a person's eating habits were disturbed. The t-test was used to conduct the statistical analysis, which revealed that male students have a more disturbed eating attitude than female students. This shows that disturbed eating behaviors are no longer limited to women but are now impacting men as well. To prevent its spread, educational institutions should monitor the dangers that have occurred in their pupils and encourage them to adopt good eating habits.

Conclusion:

Thus, it can be concluded from the result of the current study that male undergraduates are more prone toward disturbed eating habits than female undergraduates. The findings of this study can assist guidance counselors, general public, students, parents, and academic institutions in dealing with eating disorders, particularly in preventing it from the severity level.
Betrayal trauma, dissociative experiences, and posttrauma cognitions among women in a state shelter home
Authors: Kumble Chaitra Nagaraj , Suman L. N.
Published: December 2022

Context:

There is a long history of interpersonal trauma in women, and the risk factors and mental health consequences have been well studied. Betrayal trauma (BT) theory by Freyd talks about the specific kind of trauma perpetrated by someone close to the victim, which may lead to increased dissociative responses. Recent research extends the theory to explain the role of posttrauma appraisals playing a mediating role in the development of psychopathological responses.

Aim:

The aim of this study was to explore trauma history, BT, and dissociative experiences among women in a Government Reception Centre.

Setting:

The sample included 30 women from the Reception Centre, Bangalore.

Subjects and Methods:

Data were obtained using a Sociodemographic Data Sheet, Brief BT Survey (revised), the Dissociative Experiences Scale, Posttrauma Cognitions Inventory and a visual analog scale for assessing psychological distress.

Statistical Analysis Used:

Descriptive statistics and nonparametric inferential statistics were used for quantitative analysis.

Results:

All the women in the sample had experienced BT directly or as witnesses. There was no significant difference in dissociation between high- and low-BT groups. The presence of negative cognitions toward oneself was associated with increased dissociative experiences. Negative cognitions toward self and depersonalization experiences were higher in the group with severe physical trauma than the group without.

Conclusion:

The article highlights the high prevalence of betrayal trauma, and risk for trauma-related psychopathology and revictimization that go unassessed in government shelter homes, while reiterating the need for a trauma-informed care approach to intervention.
Psychosis following COVID-19 vaccination
Authors: Krishna Javangula Swetha , Harshitha Veeramachaneni , Endreddy Ananda Reddy , Seshamma V. Venkata
Published: December 2022

COVID-19 infection has caused a lot of pain and suffering to date, but it is still showing catastrophic effects on humanity even after developing and effectively using the COVID vaccines for the containment of the virus. With the prevailing pandemic, there are new problems arising postvaccination in people, especially the neuropsychiatric manifestations. The present case report is of a 46-year-old single mother who completed graduation and working as a primary school teacher brought to our outpatient department with complaints of muttering to herself, decreased sleep and appetite, hearing the voice of her husband who died 15 years back, and being fearful after 3 days of receiving the second dose of Covishield vaccine. She got prescribed tablet risperidone 2 mg (bd) and tablet clonazepam 0.5 mg at night. In the absence of any other causative explanations, a temporal association is that the presentation could have been triggered as a result of complications relating to COVID-19 vaccination.
Neuropsychological impairments in a young-onset Marchiafava–Bignami disease with alcohol-dependence syndrome
Authors: Penubarthi Sravanthi , Miryala Raghunath , Vatte Vishwak Reddy , Kandrakonda Srinivas
Published: December 2022

The neuropsychological aspects of Marchiafava–Bignami disease (MBD) have not been reported in detail in the medical literature, despite various reports mentioning that chronic alcoholism is the most common etiology for the same. The condition is predominant in men around the fourth to sixth decades with a mean age of 45 years. To the best of our knowledge, we report a case of early onset of MBD in a 32-year-old man diagnosed with alcohol-dependence syndrome, who presented with cognitive impairment, behavioral issues, and gait abnormalities after a period of loss of consciousness of around 4 days. Along with symptomatic treatment, the patient was given thiamine supplementation, parenteral for a week, followed by oral thiamine. There was a slow improvement in his cognitive symptoms, while the rest of the symptoms improved within a month of starting medications.
Perceived difficulties of the family member of a survivor of rape with multiple disabilities in accessing care and support
Authors: Vranda Mysore Narasimha , Kumar Channaveerachari Naveen , Febna Moorkath , Ammapattian Thirumoorthy , Shiri Sahana Supriya
Published: December 2022

Gender-based violence against women and girls is a major public health issue. Women with multiple disabilities are more vulnerable to experience sexual violence due to pre-existing vulnerability factors than non-disabled. In this case report, we are present a case report of perceived challenges and difficulties experienced by the family member of a 26 years old survivor of sexual assault with multiple disabilities in availing health and psychosocial services in the community.
Effectiveness of family-focused psycho-education on expressed emotions among caregivers of persons with bipolar affective disorder
Authors: Ashalata K. , Koujalgi Sateesh Rangarao
Published: December 2022

Background:

Expressed emotion (EE) is a significant characteristic of the family milieu that has been found to predict symptom relapse in bipolar affective disorder (BPAD). The need for family-focused psychosocial intervention in BPAD suitable to our culture is poorly understood. Therefore, this study was designed to discover the effectiveness of Barcelona family-focused group psycho-education on EE in BPAD.

Aim:

The aim of the present study is to assess the effectiveness of family-focused psycho-education on EE among caregivers of patients with BPAD.

Materials and Methods:

The interventional study included forty primary caregivers of patients diagnosed with BPAD. Caregivers were randomly allocated into five groups of eight each. BPAD was diagnosed by using the International Classification of Diseases-10, Classification of Mental and Behavioral Disorders, and Diagnostic Criteria for Research. The researcher had used the purposive sampling technique. Assessed EE by administering Family Attitude Scale (FAS) at pre- and postinterventional phases, family-focused group psycho-education module of Barcelona was adopted as an interventional method.

Results:

Totally 23 (57.5%) male and 17 (50.75%) female caregiver respondents participated in the study. The mean value of the overall pretest FAS score of total respondents was 94.33, critical comments = 43.75, hostility actions = 29.98, and distancing = 28.53. With EE dimensions, a greater difference in pre-intervention mean of 94.33±8.48 and a post-intervention value of 37.28±13.07 could be observed (t = 25.20, P = 0.001 and P< 0.05, respectively).

Conclusion:

Barcelona family-based psycho-educational intervention model is effective in reducing higher EE in families of patients with BPAD.
The Vulnerability of Withdrawal
Authors: Willems Brian
Published: December 2022

In Tao Lin's early books Eeeee Eee Eeee (2007), Bed (2007), Shoplifting from American Apparel (2009), and Richard Yates (2010) vulnerability is linked to a lack of context. Passages and sentences are semantically removed enough from each other that a space of vulnerability opens in which the unexpected can happen. Using the work of Quentin Meillassoux, Judith Butler, Jacques Rancière, and Levi Bryant, among others, this sense of vulnerability is argued to be the primary experience of our lives, but we often forget it. Lin's work makes this primary vulnerability visible in the three works analyzed using three different techniques: incomplete information, withdrawn context, and a monstrous vulnerability. In this sense, the author makes his writing vulnerable to the very problems that it foregrounds.
La villa sur le lac de Boris Pahor en italien et sa traduction indirecte en français
Authors: Mezeg Adriana , Grego Anna Maria
Published: December 2022

Le présent article se propose d’observer la traduction des realia dans les versions italienne et française du roman Vila ob jezeru (respectivement La villa sul lago et La villa sur le lac) de Boris Pahor. La villa sur le lac représente à ce jour le seul roman de Pahor à ne pas avoir été traduit vers le français du slovène, mais par l’intermédiaire d’une autre langue, à savoir l’italien. Après une courte présentation de l’œuvre et du concept de traduction indirecte, l’article se focalise sur les stratégies de traduction des mots ou expressions typiques du littoral slovène et de son arrière-pays, qui constituent la langue de Pahor, pour découvrir si ces éléments culturels, qui représentent un véritable défi de traduction, ont été gardés ou perdus non seulement dans la traduction indirecte en français, mais aussi, vu les contacts géographique, linguistique et culturel étroits entre la Slovénie et l’Italie, dans la traduction directe en italien.
Literary Translation as an Instrument of Slovenian Cultural Diplomacy with Particular Regard to Translations in German
Authors: Rozman Julija
Published: December 2022

The article discusses translation policy in Slovenia as part of the country’s cultural diplomacy. Translations of Slovenian literature, especially into German and English, are among the goals of the country’s cultural policy, in part because of Slovenia’s upcoming role as Guest of Honour at the Frankfurt Book Fair in 2023. The article analyses the role of the financial support for and promotion of translations from Slovenian into foreign languages by the Slovenian Book Agency and the Trubar Foundation. The study of subsidies for translations into German, English, French, Italian, Croatian, and Hungarian shows that while the number of subsidies for translations into German and English is high, as expected, Croatian takes the leading role among the target languages studied. This underscores the importance of the still-vibrant social and political ties stemming from the historical context of Yugoslavia. In addition to the crucial role of subsidies in exporting literature from a peripheral language such as Slovenian, the translation process and the promotion of literature depend to a considerable extent on other market actors-as the interviews with three literary experts showed.
Calculation of biodiversity parameters of epigean Hexapoda species in different anise (Pimpinella anisum L.) and fennel (Foeniculum vulgare Mill.) agro-ecosystems in Burdur Province
Authors: ERGENE Şükrü Erden , AYDIN Gökhan
Published: December 2022

This study was carried out to compare the biodiversity parameters of epigean insect species in 3 different regions with different geographical conditions. Tefenni Plain, Beyköy (Abdülmelik) Plain and Çaylı Mountain Village, which are located at 3 different altitudes, were chosen as the study area. Pitfall traps were placed in agro-ecosystems of anise and fennel in each region and epigean insect species caught with pitfall traps were checked weekly. A total of 2086 individuals belonging to 117 epigean insect species, mostly from the carabid family, were sampled. The highest number of individuals were sampled in Tf and Ta with 841 and 440, respectively. The results of Shannon-Wiener diversity were found to be the highest in Ta with 2.7893 while the lowest was found in Ca with 2.1775. Similar to Shannon-Wiener diversity results, Simpson diversity results were calculated as highest in Ta with 0.9196 and lowest in Ca with 0.7813. Simpson's dominance results determined that Ca was the highest dominant agro-ecosystem with 0.2187. The second and third most dominant agro-ecosystems were found to be Tf and Cf with 0.1847, 0.1635, respectively. According to both Shannon and Simpson Evenness; the population densities of epigean species living in Bf and Ba were found to be more balanced than in other agro-ecosystems. The percentage similarity analysis shows that the regions selected in different altitudes were more similar to each other than the plants of the same species. Contrary to expectations, it was observed that epigean insect species did not show distribution according to plant pattern and were not directly related to plants. It is thought that the epigean insect species sampled are affected by the altitude difference
Determinan Laporan Pelaksanaan Anggaran Pendapatan Belanja Daerah
Authors: Ishak Khodijah , Khoirin Kurniatul Fil , Pratama Brilianza Indra , Selamat Muhammad Isa , Junery Muhammad Fadhil
Published: December 2022

This study aims to analyze the effect of participation, clarity of targets, and budget feedback on the implementation report of the Bengkalis district revenue and expenditure budget (REB). This type of research is quantitative, with primary data in the form of a questionnaire. The population of this study was all elements of the regional secretariat of the Bengkalis district. The sampling technique used purposive sampling so that 60 samples were obtained. The data analysis technique used multiple linear regression with the help of SPPS 25 software. The results showed that participation and clarity of budget targets positively and significantly affected reports on implementing the Bengkalis district REB. Budget feedback does not affect reports on the implementation of the Bengkalis district REB. This research can be used as reference material for further research and the Bengkalis district government reporting the implementation of the REB.
Kinerja Keuangan Koperasi Sebelum Dan Saat Pandemi Covid-19 Terhadap Sisa Hasil Usaha
Authors: Ratih Nur Rahmanti , Oktaviana Dwi , Kusumaningarti Miladiah
Published: December 2022

This study analyzes the financial performance before and during the covid-19 pandemic on the operating profit. Sources of data come from primary data obtained through interviews and secondary data in the form of financial reports through documentation. The study was carried out using a quantitative descriptive method. Analysis was carried out descriptively regarding financial performance through return on assets (ROA), return on equity (ROE), and cash ratio. The study results show that financial performance before and during the covid-19 pandemic is still below cooperative financial standards and needs to produce operating profit optimally. Cooperative financial performance will have an influence on operating profit in the future. Good financial performance will be able to produce better-operating profits for cooperatives. The financial performance of cooperatives can impact obtaining profits in the future; therefore, cooperatives must manage their assets effectively and efficiently. This study can be a reference for cooperatives in running a business and increasing income.
The activity of Count Karl Ludwig von Ficquelmont in the Russian Empire, with a focus on his St. Petersburg salon
Authors: Kotoučová Anežka
Published: December 2022

The aim of the paper is to analyse the activities of the Imperial Envoy Count Karl Ludwig von Ficquelmont in the Russian Empire during the first half of the nineteenth century, with a special emphasis on his salon in St. Petersburg. This salon, which Ficquelmont ran in the years 1829–1840 with his Russian wife Darya Fyodorovna (Dolly), was located in the building of the Austrian Embassy in St. Petersburg and was the centre of not only cultural but also diplomatic life in the Russian capital. Interestingly, the cultural and artistic level was combined with the diplomatic and political level, which testifies to Ficquelmont as a host with a truly broad intellectual scope. The paper examines how these levels interacted, while pointing out that Ficquelmont made extensive use of his privileges as an influential diplomat and one who was loved at the court to help guests in his salon circumvent some Russian obstructions, including the severe censorship of that time. Ficquelmont’s most famous guest was the poet Alexander Sergeyevich Pushkin, who gained inspiration from the Austrian Embassy building for one of his famous works. In addition, Ficquelmont has connections with the Czech lands, as he and his wife are buried in Teplice, where his daughter married. Overall, the aim is to introduce Count Ficquelmont as an educated and cultured diplomat who naturally ran one of the most influential Russian salons of the first half of the nineteenth century. Within the source base, diplomatic reports (Ficquelmont sought greater rapprochement of the Austrian Empire with the Russian Empire) as well as various ego-documents, including the extensive diary of Darya Fyodorovna von Ficquelmont, and, marginally, contemporary Russian fiction are used equally. It was the salons that provided a large number of stimuli for the formation of Russian culture, and it was here that important socio-cultural topics of the time were discussed. It can thus be stated that the salons stood at the very birth and beginnings of Russian public opinion.
Defensoria Pública como importante ator social no aperfeiçoamento de políticas públicas
Authors: Rodrigues Taila
Published: December 2022

O surgimento das Defensorias Públicas ao longo da história ocorreu em razão da evolução do conceito de acesso à justiça e fruto de movimentos da sociedade. O termo e ações de assistência judiciária ofertadas pelo Estado se aperfeiçoou de modo a culminar no conceito de assistência jurídica, hoje intrinsicamente relacionado ao papel das Defensorias Públicas, no Brasil especialmente a partir da Constituição Federal de 1988. A assistência jurídica engloba a assistência judiciária e vai além, contribuindo para o acesso real dos cidadãos à justiça e a garantia de seus direitos, ou seja, o acesso à justiça no seu aspecto efetivo, integral, e não apenas formal. O avanço institucional reservado pela Constituição Federal à Defensoria Pública a coloca em posição de destaque na defesa dos direitos dos cidadãos, não explorada ainda em sua integralidade. Para além da orientação jurídica, judicial e extrajudicial, a Defensoria Pública dispõe, tendo em vista sua relação próxima e direta com a sociedade, da oportunidade de ampliar seu eixo de atuação em direção à participação na proposição e aperfeiçoamento de políticas públicas, se projetando como ator político-social relevante também para definição do arranjo social de nossa sociedade. Um passo além na evolução do acesso à justiça, entendida como justiça real, efetiva e permanente, anterior à necessidade de acionamento das instituições judiciárias.
STUDENTS OF CHUVASHIA ABOUT THE ORGANIZATION OF THE ALL-RUSSIAN POPULATION CENSUS IN 2020 AND ETHNO-CULTURAL ISSUES
Authors: Grigoriev Alexander V. , Karpov Aleksey V. , Muzyakova Alina L. , Tkachenko Vladimir G.
Published: December 2022

The relevance of the research lies in the fact that this article is one of the first in the last decade that is devoted to the study of metadata of the All-Russian Population Census of 2020. Its purpose is to study the attitude of students to the organization of the census, the structure and content of the questionnaire, forms of participation. The scientific novelty of the work is that it is the first study of the attitude of students enrolled in two universities of the Chuvash Republic to the organization of the 2020 census.

The survey of 300 young people showed no complaints about the census organization. Various points of view were expressed about the importance of the information obtained during the population censuses. The most popular among young people was participation in the event through an entry on the portal “Public Services”. The survey materials showed that for students of Chuvash nationality, data on nationality are more important than for students of Russian nationality. The Chuvash turned out to be more active participants in the census. Students reacted favorably or neutrally to the opportunity to indicate their belonging to more than one nationality and one native language during the census. At this, about a third stated that their native languages are Chuvash and Russian, which is unusual for an official survey conducted by the state.

The study results are of great practical importance and will be taken into account in the future when organizing upcoming activities on the population census.
PERSONNEL OF THE JUDICIAL AUTHORITIES OF OSTYAKO-VOGULSKY (KHANTY-MANSIYSK) NATIONAL DISTRICT IN THE 1930s – THE FIRST HALF OF THE 1950s
Authors: Kaburkin Aleksandr A.
Published: December 2022

The article provides brief information about the staff of the judicial authorities of the Ostyako-Vogulsky (later Khanty–Mansiysk) National District in the period from the early 1930s to the first half of the 1950s; its characteristic features are reflected. Attention is drawn to the qualitative characteristics of the district courts’ staff; first of all, emphasis is placed on weak professional and educational levels of judges, short periods of their activity until the early 1950s. The article presents information about the main sources containing data on employees of the judicial system. In parallel with the statement of facts, the article identifies and indicates the reasons for inappropriate qualification of judicial officers, which were primarily geographical factors due to remoteness of the territory from regional centers, lack of proper transport links, which entailed impossibility to move to improve education and to pass advanced training, and at the same time this did not contribute to attracting competent labor personnel, made it impossible to create reserves. The conclusion is formulated about the dependence of the quality of legal proceedings on the activities carried out by representatives of the judiciary. The emphasis is placed on a large coverage of judicial officers in military operations during the Great Patriotic War, proper performance of military duty by judges. The stages of the forming the district and its subsequent development in the aspect of the administrative-territorial structure of the region are outlined. The relevance and importance of the stated topic are noted. The conclusion is also made about a significant contribution of Ugra’s judicial sector to the overall development of the district.