bluuebunny/crossref_metadata_2025 huggingface dataset:
Design of a Liquid Cooler for a 100 kW Semiconductor Power Converter
Authors: Zhang R. , Golyanin A.
Published: August 2022

He focus of this research in this paper is to design a 100 kW power liquid cooler, semiconductor converter liquid cooler, thus using pulsed thermal medium circulation to increase the capacity of the cooling system on the surface of the power semiconductor device. Based on comparing the parameters of conventional and pulsed coolant circulation mode, the liquid cooling system of power semiconductor converter is studied by physical method. In laboratory testing, experiments are planned according to the order and frequency of changing device operating modes. Finally, the experimental research results are processed, and the relationship between the discharge heat power and the temperature drop and the coolant flow is established by using the mathematical statistics method. Result: Depending on the exhaust heat power and the coolant flow in the range of 3-1.5 L/min, the pulsating heat transfer enhancement in the liquid cooling system of the power semiconductor converter can increase the thermal capacity and the current load of the power semiconductor converter by a factor of almost 2.5 times, respectively. At the same time, the circulation of the coolant in the inner circuit is carried out by a hydraulic powered film pump.

Основное внимание в исследовании уделяется разработке жидкостного охладителя полупроводникового преобразователя, мощностью 100 кВт, с использованием импульсной циркуляции теплоносителя для увеличения мощности системы охлаждения на поверхности силового полупроводникового устройства. На основе сравнения параметров обычного и импульсного режимов циркуляции теплоносителя физическим методом исследована жидкостная система охлаждения силового полупроводникового преобразователя. При лабораторных испытаниях эксперименты планировались по порядку и частоте смены режимов работы прибора. Наконец, результаты экспериментальных исследований обрабатывались, и методом математической статистики устанавливалась связь между тепловой мощностью разряда, падением температуры и расходом теплоносителя. Результат: в зависимости от мощности выхлопа и расхода теплоносителя в диапазоне 3-1,5 л/мин пульсирующее усиление теплообмена в системе жидкостного охлаждения силового полупроводникового преобразователя может увеличить тепловую мощность и токовую нагрузку силового агрегата полупроводникового преобразователя почти в 2,5 раза. При этом циркуляция теплоносителя во внутреннем контуре осуществляется пленочным насосом с гидравлическим приводом.
Operation Optimization Strategy of Multi-microgrids Energy Sharing Based on Asymmetric Nash Bargaining
Authors: Kang Ch. , Zhang Z. , Kudashev S. , Liu M. , Zhang Q. , Pan J.
Published: August 2022

The accommodation of renewable energy is driving the development of energy storage technology, and shared energy storage has gained widespread attention because of its decentralized nature. In the optimal scheduling of shared energy storage, the problem of benefit distribution among multiple subjects is faced, so a shared energy storage plant operation optimization method based on Nash bargaining theory is proposed. The article constructs a joint model of shared energy storage plants and industrial users, establishes the cooperative operation model of each operator based on Nash bargaining theory, equates this nonconvex nonlinear problem into two subproblems of system revenue maximization and power transaction payment bargaining according to the mean value inequality, and uses the alternating direction multiplier method to solve them in a distributed manner. The algorithm selects three typical industrial users to participate in the joint system of shared energy storage, and through comparative analysis before and after cooperative bargaining, it is concluded that the proposed optimization method can effectively improve the benefits of each subject, while promoting the accommodation of new energy.

Размещение возобновляемых источников энергии стимулирует развитие технологий хранения энергии, а совместное хранение энергии получило широкое распространение благодаря своей децентрализованной природе. При оптимальном планировании совместного использования накопителей энергии возникает проблема распределения выгоды между несколькими субъектами, поэтому предлагается метод оптимизации работы установки совместного хранения энергии, основанный на теории сделки Нэша. Построена совместная модель общих станций хранения энергии и промышленных пользователей, определена модель совместной работы каждого оператора на основе теории сделки Нэша, эта невыпуклая нелинейная задача разделена на две подзадачи: максимизации дохода системы и согласования оплаты за транзакцию электроэнергии в соответствии с неравенством среднего значения, и для их решения распределенным способом используется метод множителей переменного направления. Алгоритм выбирает трех типичных промышленных пользователей для участия в совместной системе хранения энергии, и путем сравнительного анализа до и после совместных переговоров делается вывод, что предложенный метод оптимизации может эффективно улучшить выгоды каждого субъекта, одновременно способствуя размещению новой энергии.
Impact of Uzbekistan’s Development Strategy 2017-2021 on Central Asian Economic Integration
Authors: Jumaev E. , Bakirtas T.
Published: August 2022

This article explores the economical processes that determine the sustainable development of the state and society are directly related to the internal and external factors of the Central Asian countries. In this sense, the Uzbek society over the past five years has been oriented towards effective and comprehensive cooperation with the countries of Central Asia in the development of regional issues, the development of good neighbourly relations, the recognition of common values and interests in one place - a common goal. Regional integration of the Central Asia requires deep understanding national interests and common aims of countries in this region.

В данной статье исследуются экономические процессы, определяющие устойчивое развитие государства и общества, напрямую связанные с внутренними и внешними факторами стран Центральной Азии. В этом смысле узбекское общество на протяжении последних пяти лет ориентировано на эффективное и всестороннее сотрудничество со странами Центральной Азии в решении региональных вопросов, развитие добрососедских отношений, признание общих ценностей и интересов в одном месте. Региональная интеграция Центральной Азии требует глубокого понимания национальных интересов и общих целей стран этого региона.
A percepção da violência de gênero e a transmissão geracional em mulheres que sofrem violência doméstica
Authors: Conte Raquel Furtado , Von Mühlen Bruna Krimberg
Published: August 2022

O presente estudo propõe-se a refletir acerca da contribuição dos dispositivos de sexualidade e geração para a compreensão da percepção da violência de gênero em mulheres que vivenciaram essa experiência. A partir de entrevistas com 24 mulheres, as pesquisadoras investigaram a violência entre as gerações e a sua percepção sobre essa experiência. As entrevistas foram gravadas e transcritas e o referencial de análise foi o de conteúdo. As bases teóricas utilizadas foram a psicologia sistêmica e a psicanálise. Os resultados apontaram para os padrões de comportamentos que as mulheres repetem, a partir da transmissão multigeracional e da atribuição da feminilidade com a maternidade e o lugar de esposa. As conclusões revelaram que as mulheres ainda precisam resistir ao não desejo e à manutenção do lugar de escravas de seu destino.
Diálogos argumentativos de crianças em processo de alfabetização
Authors: Ribeiro Lady Daiane Martins , Fernandes Larissa Krüger , Borges Fabrícia Teixeira
Published: August 2022

Este artigo decorre de uma pesquisa sobre a construção do processo argumentativo de crianças em processo de alfabetização de uma escola pública no sudoeste goiano. O objetivo foi o de identificar e analisar os diálogos argumentativos das crianças durante uma roda de conversa mediada pela leitura dialógica do livro O menino que aprendeu a ver. Tomando por base teórica as noções conceituais a respeito da linguagem discutidas pela Psicologia Cultural e no pensamento dialógico do Círculo de Bakhtin, observamos que os diálogos argumentativos produzidos pelas crianças foram mobilizados pela entrada do “outro” no discurso, denominados neste estudo como disparadores argumentativos, tais como as intervenções da pesquisadora, as falas dos colegas e o texto literário.
Ideais liberais e a inclusão educacional e do trabalho: uma aproximação à temática de gênero, com foco nas mulheres com deficiência
Authors: De Lima Costa Laureane Marília , Da Silva Claudionor Renato
Published: August 2022

Este artigo tem como objeto as políticas públicas inclusivas sob o ideal liberal, se desdobrando nas questões educacionais e de trabalho, e refletindo sobre a intersecção entre deficiência, classe e gênero. Objetiva discutir a influência dos organismos internacionais sobre os avanços nos documentos legais brasileiros em relação às pessoas com deficiência e as limitações da efetivação de suas propostas dado o processo de reforma do Estado. Com metodologia de pesquisa bibliográfica o texto apresenta como principal resultado a evidência de que as políticas existentes, de cunho liberal, estão na contramão das demandas e necessidades advindas da realidade da inclusão educacional e do trabalho e mais na contramão ainda, em se tratando das mulheres com deficiência.
karatê na Educação em tempo integral: diálogos com a pedagogia Pós-crítica
Authors: Potulski Alexsandra Aline , Jacondino Eduardo Nunes
Published: August 2022

O presente artigo traz reflexões sobre a prática da arte marcial karatê na educação em tempo integral, interligando aspectos relacionados à pedagogia pós-crítica, influenciada pelo pós-estruturalismo. O objetivo do trabalho é,  portanto, conceituar os três temas abordados: karatê, educação em tempo integral e pedagogia pós-crítica. A metodologia adotada é o pós-estruturalismo. O questionamento a ser aclarado durante o trabalho é: de que modo a educação em tempo integral, por meio da prática do karatê, compreende um olhar sobre o cuidado de si do sujeito educacional a ser lida pela pedagogia pós-crítica? Trata-se de uma pesquisa bibliográfica efetuada por meio de referencial teórico.
Recontextualização de concepções de aprendizagem nos âmbitos governamental e escolar
Authors: Kummer Daiane Aline , Arnt Janete Teresinha
Published: August 2022

O objetivo deste trabalho é identificar princípios subjacentes a perspectivas que fundamentam concepções de aprendizagem nas Diretrizes Curriculares Nacionais para o Ensino Médio (BRASIL, 2012). A partir disso, verificamos possibilidades de recontextualização desses princípios em atividades de ensino de inglês em livros didáticos. A análise do documento foi realizada a partir da identificação de itens linguísticos (BARTON, 2004) que fizessem referência a tais perspectivas. Os resultados evidenciam um alinhamento do documento à perspectiva sociocultural e a possibilidade de uma transposição dessa perspectiva no contexto escolar a partir de atividades de livros didáticos discutidos no estudo, o que contribui para a promoção de um ensino contextualizado que estimule a conscientização do estudante.
As charges e a produção de sentidos: por um diálogo entre a imagem e o ensino
Authors: Ribeiro Ormezinda Maria , Araújo Susana Menezes
Published: August 2022

Os avanços tecnológicos propiciaram o surgimento de textos multimodais, apontando-os como recursos pedagógicos para a ampliação das competências linguísticas dos estudantes, já que sua leitura exige a análise de elementos distintos que vão além da linguagem verbal. O trabalho visa discutir as concepções de textos multimodais e as exigências de leitura que esses demandam. Tais textos são apresentados considerando o cruzamento de leitura que exigem. Analisam-se significados de elementos presentes em charges como desaprovação ao aumento do preço do Diesel, em 2018, destacando-se que o trabalho com esse gênero se constitui em recurso pedagógico no desenvolvimento de habilidades essenciais para o uso eficiente da língua nas mais diversas interações.
Quem tem medo do Queer? Quando a potência política da arte cede à cafetinagem
Authors: Inocêncio Adalberto Ferdnando , Gonçalves Cléberson Diego
Published: August 2022

Este artigo insere-se no campo das micropolíticas e das posições de censura imanentes em um contexto político mais amplo, o do inconsciente colonial-capitalístico. Analisa-se, aqui, a captura do desejo de criação, considerando a censura no campo da arte ocorrida no ano de 2017 com a exposição Queermuseu, suspensa em Porto Alegre, após protestos contra o Santander Cultural. Mergulhou-se nos discursos, obras e relações inscritas no percurso do olhar opressor sobre as artes queer, e as relações crescentes de um desejo arcaico, mas, ao mesmo tempo, recente, entre neoliberalismo e conservadorismo que assolam o contexto brasileiro. A materialidade discursiva presente em Queermuseu pode seduzir para a quebra de transe do inconsciente colonial-cafetinístico, e sobre isso elucidamos as práticas de censura e denunciamos os discursos que permeiam nossa realidade.
Spatial clustering of waste reuse in a circular economy: A spatial autocorrelation analysis on locations of waste reuse in the Netherlands using global and local Moran’s I
Authors: Tsui Tanya , Derumigny Alexis , Peck David , van Timmeren Arjan , Wandl Alexander
Published: August 2022

In recent years, implementing a circular economy in cities has been considered by policy makers as a potential solution for achieving sustainability. Existing literature on circular cities is mainly focused on two perspectives: urban governance and urban metabolism. Both these perspectives, to some extent, miss an understanding of space. A spatial perspective is important because circular activities, such as the recycling, reuse, or storage of materials, require space and have a location. It is therefore useful to understand where circular activities are located, and how they are affected by their location and surrounding geography. This study therefore aims to understand the existing state of waste reuse activities in the Netherlands from a spatial perspective, by analyzing the degree, scale, and locations of spatial clusters of waste reuse. This was done by measuring the spatial autocorrelation of waste reuse locations using global and local Moran’s I, with waste reuse data from the national waste registry of the Netherlands. The analysis was done for 10 material types: minerals, plastic, wood and paper, fertilizer, food, machinery and electronics, metal, mixed construction materials, glass, and textile. It was found that all materials except for glass and textiles formed spatial clusters. By varying the grid cell sizes used for data aggregation, it was found that different materials had different “best fit” cell sizes where spatial clustering was the strongest. The best fit cell size is ∼7 km for materials associated with construction and agricultural industries, and ∼20–25 km for plastic and metals.The best fit cell sizes indicate the average distance of companies from each other within clusters, and suggest a suitable spatial resolution at which the material can be understood. Hotspot maps were also produced for each material to show where reuse activities are most spatially concentrated.
Recent progress on hybrid reactive-extractive distillation for azeotropic separation: A short review
Authors: Kong Zong Yang , Sunarso Jaka , Yang Ao
Published: August 2022

The reactive-extractive distillation (RED) has the advantages of combining the beneficial features of both reaction and separation processes. Relative to the conventional reactive or extractive distillation-based processes, the RED is also less energy intensive as it relies on the reaction heat produced for the subsequent separation process. Therefore, the application of RED for ternary azeotropic separation has become the subject of popular interest, as evident by the increasing number of publications since 2020. This review paper is the first that puts together, in a chronological manner, all the existing studies on the RED to date, starting from the initial three column reactive-extractive distillation (TCRED) to the most recent dividing wall reactive-extractive distillation (DW-RED), for ternary azeotropic separation, so that the rapid progress in this area is summarised and any existing gaps in these studies become easier to identify for future work. The last part of this review provides three potential areas for future work, i.e. analysis of the sustainability of RED, combination of different process intensification strategies to improve the energy efficiency and separation performance, and further exploration on the control studies for the RED.
Influence of carrier effect on Pd/Al2O3 for methane complete catalytic oxidation
Authors: Peng Shengpan , Ma Ziran , Ma Jing , Wang Hongyan , Chen Jingyun , Wei Hui , Li Yonglong , Ao Zhimin , Wang Baodong
Published: August 2022

Pd/Al2O3 catalysts modified by different chemical elements (Mg, Si, Ce, and Zr) were tested for methane (CH4) catalytic combustion, and PdO nanoparticles loaded on modified Al2O3 were systematically studied. These conditions assess the carrier effects of Pd/Al2O3 and acid strength influences on CH4 combustion. We observed carrier effects on activation energy through tuning Pd 3d binding energies (BEs) and on pre-exponential factors (A) through Pd dispersion and acidity on supports. When the BE of Pd 3d5/2 is 337.3 eV, PdO nanoparticles loaded on modified Al2O3 have excellent activity in cracking the C−H bond of CH4, which leads to the lowest activation energy (Ea), regardless of the size effect of the PdO nanoparticle. Furthermore, a theoretical construction that acid sites on catalysts promote the reversible elementary step (2Pd−OH ↔ Pd−O* + Pd* + H2O) right shifts improving the A dependency on the quantity of exposed Pd* and Pd−O*. As a result, Al2O3, as the carrier, not only modifies the electronic characteristics and size of supported PdO nanoparticles but also participates in the reaction process via acid sites on the surface of Al2O3.
Safety and Efficacy of Contemporary Drug-Eluting Stents in Patients With ST-Segment Elevation Myocardial Infarction and a High Ischemic Risk
Authors: Lee Oh-Hyun , Kim Yongcheol , Son Nak-Hoon , Cho Deok-Kyu , Kim Jung-Sun , Kim Byeong-Keuk , Choi Donghoon , Hong Myeong-Ki , Jeong Myung Ho , Jang Yangsoo
Published: August 2022

Background

In patients with ST-elevation myocardial infarction (STEMI) with a high risk of ischemic events, the safety and efficacy of drug-eluting stent (DES) are unclear.

Methods

Based on the nationwide, multicenter, prospective registry, we selected 1,592 patients who underwent primary percutaneous coronary intervention (PCI) with everolimus-(EES) and zotarolimus-eluting stent (ZES) for STEMI with a high risk of an ischemic event. The occurrence of target lesion failure (TLF) for 3 years, defined as the composite of cardiac death, target vessel myocardial infarction (TV-MI), and ischemia-driven target lesion revascularization (ID-TLR), was evaluated.

Results

The prevalence of high ischemic risk features was observed in 43.4% (2,744/6,325) of overall patients with STEMI. Among them, a total of 1,078 and 514 patients were treated with EES and ZES, respectively. At 3 years, the risk of TLF was not significantly different between the two groups (p = 0.93). In addition, the incidence of cardiac death, TV-MI, ID-TLR, and definite/probable stent thrombosis (ST) were also not different between the two groups. Moreover, elderly patients (age > 75 years) and PCI for the left main disease were identified as independent predictors of TLF.

Conclusion

Implantation of EES or ZES provided comparable clinical outcomes in STEMI patients and high ischemic risks.
Case report: Traumatic ventricular aneurysm combining tricuspid valve avulsion in a child: Diagnostic findings and treatment protocols
Authors: Zhang Dengshen , Wei Shan , Tao Wenhong , Liao Yuanfeng , Xiao Ruihan , Liu Daxing
Published: August 2022

This case report is an extremely rare case of a traumatic left ventricular aneurysm in a 3-year-old child who also had tricuspid valve avulsion due to blunt trauma. The diagnostic findings and treatment protocols are discussed to provide a clinical reference.
CDK9 binds and activates SGK3 to promote cardiac repair after injury via the GSK-3β/β-catenin pathway
Authors: Sun Jiateng , Yang Tongtong , Wei Tianwen , Zhou Liuhua , Shan Tiankai , Chen Jiawen , Gu Lingfeng , Chen Bingrui , Liu Liu , Jiang Qiqi , Du Chong , Ma Yao , Wang Hao , Chen Feng , Guo Xuejiang , Ji Yong , Wang Liansheng
Published: August 2022

The mammalian heart possesses entire regeneration capacity after birth, which is lost in adulthood. The role of the kinase network in myocardial regeneration remains largely elusive. SGK3 (threonine-protein kinase 3) is a functional kinase we identified previously with the capacity to promote cardiomyocyte proliferation and cardiac repair after myocardial infarction. However, the upstream signals regulating SGK3 are still unknown. Based on the quantitative phosphoproteomics data and pulldown assay, we identified cyclin-dependent kinase 9 (CDK9) as a novel therapeutic target in regeneration therapy. The direct combination between CDK9 and SGK3 was further confirmed by co-immunoprecipitation (Co-IP). CDK9 is highly expressed in the newborn period and rarely detected in the adult myocardium. In vitro, the proliferation ratio of primary cardiomyocytes was significantly elevated by CDK9 overexpression while inhibited by CDK9 knockdown. In vivo, inhibition of CDK9 shortened the time window of cardiac regeneration after apical resection (AR) in neonatal mice, while overexpression of CDK9 significantly promoted mature cardiomyocytes (CMs) to re-enter the cell cycle and cardiac repair after myocardial infarction (MI) in adult mice. Mechanistically, CDK9 promoted cardiac repair by directly activating SGK3 and downstream GSK-3β/β-catenin pathway. Consequently, our study indicated that CDK9 might be a novel target for MI therapy by stimulating myocardial regeneration.
Transcriptional bursts and heterogeneity among cardiomyocytes in hypertrophic cardiomyopathy
Authors: Burkart Valentin , Kowalski Kathrin , Aldag-Niebling David , Beck Julia , Frick Dirk Alexander , Holler Tim , Radocaj Ante , Piep Birgit , Zeug Andre , Hilfiker-Kleiner Denise , dos Remedios Cristobal G. , van der Velden Jolanda , Montag Judith , Kraft Theresia
Published: August 2022

Transcriptional bursting is a common expression mode for most genes where independent transcription of alleles leads to different ratios of allelic mRNA from cell to cell. Here we investigated burst-like transcription and its consequences in cardiac tissue from Hypertrophic Cardiomyopathy (HCM) patients with heterozygous mutations in the sarcomeric proteins cardiac myosin binding protein C (cMyBP-C, MYBPC3) and cardiac troponin I (cTnI, TNNI3). Using fluorescence in situ hybridization (RNA-FISH) we found that both, MYBPC3 and TNNI3 are transcribed burst-like. Along with that, we show unequal allelic ratios of TNNI3-mRNA among single cardiomyocytes and unequally distributed wildtype cMyBP-C protein across tissue sections from heterozygous HCM-patients. The mutations led to opposing functional alterations, namely increasing (cMyBP-Cc.927−2A>G) or decreasing (cTnIR145W) calcium sensitivity. Regardless, all patients revealed highly variable calcium-dependent force generation between individual cardiomyocytes, indicating contractile imbalance, which appears widespread in HCM-patients. Altogether, we provide strong evidence that burst-like transcription of sarcomeric genes can lead to an allelic mosaic among neighboring cardiomyocytes at mRNA and protein level. In HCM-patients, this presumably induces the observed contractile imbalance among individual cardiomyocytes and promotes HCM-development.
Cardiac resynchronization therapy in heart failure patients by using left bundle branch pacing
Authors: Gu Ying , Li Yanming , Zhu Ying , Lin Xiuyu , Tian Tian , Zhang Qigao , Gong Jianbin , Wang Lei , Li Jianhua
Published: August 2022

Background

Left bundle branch pacing (LBBP) is emerging as an effective alternative to achieve cardiac resynchronization therapy (CRT) and improve heart function. The purpose of our study was to investigate the feasibility and efficacy of LBBP in heart failure patients with left ventricular ejection fraction (LVEF) <50% and left bundle branch block (LBBB).

Methods

All patients with complete LBBB and LVEF <50% were retrospectively included in the study from April 2018 to April 2021 and underwent CRT via LBBP implantation. ECG, pacing parameters, the New York Heart Association (NYHA) functional class, echocardiographic measurements, and complications were recorded and analyzed at implant and during follow-up of 1, 6, and 12 months.

Results

Left bundle branch pacing was successful in all 34 patients (mean age 65.6 ± 11.2 years, 67.6% men). A significant decrease in QRS duration (QRSd) was observed after the LBBP operation for 1 month (153.2 ± 1.7 vs. 111.9 ± 2.6 ms, p < 0.01). LBB capture threshold and R-wave amplitude remained stable at 12-month follow-up when compared with implantation values (0.62 ± 0.13 V @ 0.4 ms vs. 0.73 ± 0.21 V @ 0.4 ms, 12.02 ± 5.68 mV vs. 8.58 ± 4.09 mV, respectively). LVEF increased significantly (35.28 ± 1.70% vs. 51.09 ± 1.71%, p < 0.01) accompanied with reduced left ventricular end-diastolic dimension (LVEDd; 65.3 ± 1.99 vs. 53.58 ± 2.07 mm, p < 0.01) and left atrial dimension (LAD; 49.03 ± 1.32 vs. 40.67 ± 1.58 mm, p < 0.01). Normalized LVEF (LVEF ≥ 50%) was found in 70.5% of patients at 12 months. The NYHA classification, brain natriuretic peptide (BNP), and 6-minute walk test (6MWT) were significantly improved at follow-up of 12 months (all p < 0.01 vs. baseline). No deaths or heart failure hospitalizations were observed during the follow-up period.

Conclusion

The current work suggested that LBBP was feasible with a high success implantation rate and effective to correct LBBB and improved left ventricular structure and function with a low and stable pacing threshold.
Anesthetic-, irrigation- and pain-free dentistry? The case for a femtosecond laser enabled intraoral robotic device
Authors: Rapp Ludovic , Madden Steve , Rode Andrei V. , Walsh Laurence J. , Spallek Heiko , Nguyen Quan , Dau Van , Woodfield Peter , Dao Dzung , Zuaiter Omar , Habeb Alaa , Hirst Timothy R.
Published: August 2022

By leveraging ultrashort pulse laser and micro-electromechanical systems (MEMS) technologies, we are developing a miniaturized intraoral dental robotic device that clamps onto teeth, is remotely controlled, and is equipped with a focusing and scanning system to perform efficient, fast, and ultraprecise laser treatments of teeth and dental restorative materials. The device will be supported by a real-time monitoring system for visualization and diagnostic analysis with appropriate digital controls. It will liberate dentists from repetitive manual operations, physical strain and proximity to the patient's oropharyngeal area that potentially contains infectious agents. The technology will provide patients with high-accuracy, minimally invasive and pain-free treatment. Unlike conventional lasers, femtosecond lasers can ablate all materials without generating heat, thus negating the need for water irrigation, allowing for a clear field of view, and lowering cross-infection hazards. Additionally, dentists can check, analyze, and perform precise cutting of tooth structure with automatic correction, reducing human error. Performing early-stage diagnosis and intervention remotely will be possible through units installed at schools, rural health centers and aged care facilities. Not only can the combination of femtosecond lasers, robotics and MEMS provide practical solutions to dentistry's enduring issues by allowing more precise, efficient, and predictable treatment, but it will also lead to improving the overall access to oral healthcare for communities at large.
Impacts of ocean-atmosphere teleconnection patterns on the south-central United States
Authors: Rohli Robert V. , Snedden Gregg A. , Martin Elinor R. , DeLong Kristine L.
Published: August 2022

Recent research has linked the climate variability associated with ocean-atmosphere teleconnections to impacts rippling throughout environmental, economic, and social systems. This research reviews recent literature through 2021 in which we identify linkages among the major modes of climate variability, in the form of ocean-atmosphere teleconnections, and the impacts to temperature and precipitation of the South-Central United States (SCUSA), consisting of Arkansas, Louisiana, New Mexico, Oklahoma, and Texas. The SCUSA is an important areal focus for this analysis because it straddles the ecotone between humid and arid climates in the United States and has a growing population, diverse ecosystems, robust agricultural and other economic sectors including the potential for substantial wind and solar energy generation. Whereas a need exists to understand atmospheric variability due to the cascading impacts through ecological and social systems, our understanding is complicated by the positioning of the SCUSA between subtropical and extratropical circulation features and the influence of the Pacific and Atlantic Oceans, and the adjacent Gulf of Mexico. The Southern Oscillation (SO), Pacific-North American (PNA) pattern, North Atlantic Oscillation (NAO) and the related Arctic Oscillation (AO), Atlantic Multidecadal Oscillation/Atlantic Multidecadal Variability (AMO/AMV), and Pacific Decadal Oscillation/Pacific Decadal Variability (PDO/PDV) have been shown to be important modulators of temperature and precipitation variables at the monthly, seasonal, and interannual scales, and the intraseasonal Madden-Julian Oscillation (MJO) in the SCUSA. By reviewing these teleconnection impacts in the region alongside updated seasonal correlation maps, this research provides more accessible and comparable results for interdisciplinary use on climate impacts beyond the atmospheric-environmental sciences.
Supporting children’s social play with peer-based intervention and instruction in four inclusive Swedish preschools
Authors: Gladh Maria , Siljehag Eva , Westling Allodi Mara , Odom Samuel L.
Published: August 2022

This multiple case study investigated a peer-based intervention and instruction (PBII) for social play, Play Time/Social Time (PT/ST), in four inclusive Swedish preschools. PT/ST contains 28 learning activities where children playfully practice six social skills with significance for social play and friendships. One teacher in each preschool was trained and instructed to implement PT/ST, two with coaching early in the implementation, and two without. At each preschool, one child with special educational needs (SEN) in social play (n = 4) and one or two socially skilled peers (n = 6) participated. The study aimed to explore how the teachers perceived the influence of PT/ST on social engagement and social play skills in the children with SEN, with/without coaching, and if PT/ST supported social play between the children with and without SEN. It also aimed to examine the feasibility of PT/ST and the influence on preschool inclusion quality in the preschools, with/without coaching. Observational assessments and video observations were used. The results indicate that PT/ST was beneficial for the children with SEN to engage in social play with peers and practice social skills, and for the preschool’s inclusion quality regarding involvement in peer interactions and guidance in play, both with/without coaching for the teachers. However, the coaching strengthened the intervention fidelity. Social play occurred between the children with and without SEN in activities where they seemed similarly attracted by the toys and play materials and when they all could engage in the play goals, tasks, and roles. For this, they sometimes needed instructions and encouragement from the teachers.
Research on the user comprehensive energy consumption decision-making method based on the evolutionary game
Authors: Zhu Xian Feng , Yao Jun Wei , Xie Qiong Yao , Dai Lu , Yang Chu Yuan , Wang Hai Liang , He Qi , Deng Ling , Shen Ran , Zhou Xiao Xia
Published: August 2022

With the increasing diversification of human energy consumption forms in the integrated energy market, analyzing the comprehensive energy consumption behavior of user groups according to their changing energy demand characteristics is an important issue to be urgently addressed. To solve this problem, an analysis method of user’s comprehensive energy consumption behavior based on the evolutionary game is proposed in this article. First, three types of users including residents, large industries, and commercial users are considered for this purpose. Then, a utility model which takes into account the energy consumption characteristics of these users and their comfort factors is constructed based on the subjective and objective combination weighting method. Thereafter, an evolutionary game theory is used to analyze the dynamic selection process for users by selecting energy suppliers and then using the selection results when the evolutionary equilibrium is reached. Finally, the model is solved by using a distributed iterative method. The correctness and validity of the proposed method are verified by the simulation results.
Rural landscape characterization from the perspective of the tourist using online reviews: A case study of Yayou Gou Village in Shandong, China
Authors: Zhuang Qianda , Hussein Mohd Kher , Mohd Ariffin Noor Fazamimah , Mohd. Yunos Mohd. Yazid , Chen Shuzhen
Published: August 2022

In the field of landscape characterization, it is difficult to obtain the tourists’ perceptions of a landscape. To overcome these drawbacks, online available reviews and comments from tourists can be utilized as an alternative way to characterize a landscape. This study examined the rural landscape characterization in Yayou Gou Village, which is a unique attraction in Shandong, China. A qualitative content analysis was undertaken on the tourists’ comments and reviews of Yayou Gou Village on tourist websites and social media platforms, including Qnar, Meituan, Ctrip, Dianping and Sina Microblog. NVivo 12 was used for the content analysis and qualitative coding. A variety of natural, cultural, and social, perceptual, and seasonal characteristics of a rural landscape, as well as facilities and infrastructure were revealed. Cultural and social landscape characters including performance landscape and festival activities, building, educational and home-stay landscape, diet landscape, and night landscape, which are obviously richer than other aspects in this rural village. Natural, perceptual, and seasonal landscape characters are not fully exploited for rural tourism and landscape. This study suggests that natural, cultural, and social rural landscape, and facility and infrastructure were influenced by spatial, seasonal, and perceptual dimensions. Suggestions for better landscape conservation and management can be acquired through the characterization process. This study provides an innovative approach for landscape characterization with online review data from various tourists. It demonstrates that online social media data contain abundant information about the landscape that they have visited and could be well used to explore the landscape’s characteristics in rural areas.
Drift macroalgae positively influence seagrass-associated nekton communities of the northern Gulf of Mexico
Authors: Correia Kelly M. , Alford Scott B. , Belgrad Benjamin A. , Darnell Kelly M. , Darnell M. Zachary , Furman Bradley T. , Hall Margaret O. , Hayes Christian T. , Martin Charles W. , McDonald Ashley M. , Smee Delbert L.
Published: August 2022

Drift macroalgae, often found in clumps or mats adjacent to or within seagrass beds, can provide additional food resources and habitat complexity, leading to increased animal abundance, but large concentrations can also inhibit faunal movements, smother benthic communities, and contribute to hypoxia, reducing nekton abundance. Despite its ubiquity, few studies have quantified drift macroalgal prevalence over large spatial scales or its effects on seagrass-associated nekton, hindering our understanding of the functional role of drift macroalgae in ecosystems. We quantified the relationship between drift macroalgal biomass and the seagrass-associated nekton community within five estuaries spanning 2000 km across the northern Gulf of Mexico. Overall, increases in macroalgal biomass within seagrass meadows significantly influenced community structure, increasing shrimp, crab, and fish abundances, but the effect varied by region. Relationships between species richness, diversity, organism size, and macroalgal biomass were not observed, suggesting that drift macroalgae provide additional habitat but not necessarily new niche space. Small nekton play a vital role in many local fisheries, providing valuable food resources for fish and invertebrates. Increased recruitment into macroalgae can benefit local fisheries by providing shelter and increased food resources, which may increase the survival, growth, and population size of recreationally and economically important species. While excess levels of drift macroalgae can negatively impact benthic plant and animal communities, particularly in eutrophic areas, the moderate levels observed during this survey were associated with positive effects on organismal abundance, suggesting that drift algal dynamics should be considered in habitat-based management strategies for coastal estuaries.
Organizational Agrarian Protection: A Roadmap to Sustainable Green Rural Development
Authors: Sun Yunpeng , Guan Weimin , Li Ying , Qu Tingting
Published: August 2022

To achieve its extraordinary goal of attaining the top carbon level in 2025 and eliminating carbon bias by 2045, Pakistan needs to focus on reducing carbon emissions in rural areas. Insurance for farmers is seen as a viable risk management and insurance strategy that might help spread the risk of agricultural activities and promote green rural development. In the present study, a multistage dynamic verified model was conducted from 2000 to 2019 in Pakistan, to assess the influence of a strategy of planned rural protection on green horticulture outcomes, fundamentally to characterize the unique impact system. The results indicate that rural fossil fuel byproducts are rising steadily, and implementing an agricultural protection plan significantly reduce these byproducts. In addition, this research provides practical ideas for a low-carbon rural turn of events and the formulation of vital macroeconomic horticulture techniques. It confirms the positive outcomes for strategically located agricultural insurance, and provides critical contract suggestions for reducing rural fossil fuel byproducts, and controlling initiatives in Pakistan and other countries.
The dynamic effect of information and communication technology and renewable energy on CO2 emission: Fresh evidence from panel quantile regression
Authors: Wen Yuzhao , Shabbir Malik Shahzad , Haseeb Mohammad , Kamal Mustafa , Anwar Ahsan , Khan Mohammad Faisal , Malik Summaira
Published: August 2022

Over the last few years, the rapid growth of information and communication technologies (ICT) has contributed to every sector of the economy; however, the environmental consequences of ICT should not be overlooked. In doing so, this research investigated the asymmetric impact of ICT, renewable energy consumption (RENE), economic growth (GDP), financial development (FD), and population (POP) on CO2 emissions (CE) in the MINT countries over the period from 1990 to 2018. For this purpose, this study used STIRPAT and quantile regression. The preliminary outcomes reject the assumption of data normality; therefore, it is very necessary to use the quantile regression (QR), as the QR technique can deal with structural changes, outliers, and data non-normality. The results of QR indicate that ICT reduce carbon emissions across all the quantiles (1st quantile to 9th quantile). Similarly, RENE impedes the carbon emissions across all (1st–9th) quantiles. On the other hand, FD, GDP, and POP increase the carbon emissions across all the quantiles (1st–9th). These outcomes purposed appropriate policy implications for MINT countries.
Can green finance improve carbon emission efficiency? Evidence from China
Authors: Liang Jinhao , Song Xiaowei
Published: August 2022

The improvement of carbon emission efficiency and the realization of the goal of “carbon peaking and carbon neutrality” are the key issues that China needs to solve urgently at this stage. The green and low-carbon transformation of the economy requires sufficient financial support. Whether green finance is an opportunity to improve China’s carbon emission efficiency is worth studying. For the aim, based on the macro-panel data of 30 provinces in China from 2010 to 2019, this paper uses fixed effect model and spatial Durbin model to study the impact of green finance on regional carbon emission efficiency. The results show that: First, the development of green finance can improve the carbon emission efficiency; Second, in addition to the “local effect”, the influence of green finance on carbon emission efficiency has a “neighborhood effect”, that is, it has a spatial spillover effect on carbon emission efficiency in neighboring areas, and this effect only exists in a short time; Third, the impact of green finance on carbon emission efficiency is heterogeneous in different regions with different environmental regulations. This paper has reference significance for green finance development and the implementation of the goal of “carbon peaking and carbon neutrality” in China.
Executive equity incentives, employee stock ownership plans, and enterprise performance: Empirical evidence based on environmental uncertainty
Authors: Tian Zhihao
Published: August 2022

Taking China’s A-share listed companies from 2014 to 2021 as the research sample, this article verifies the differential impact of executive equity incentive and employee stock ownership plan on enterprise performance and examines the economic consequences of their implementation under the influence of environmental uncertainty, the nature of property rights, and the quality of external audit. The results show that 1) there are significant differences between executive equity incentive and employee stock ownership plan on enterprise performance. 2) The effect of executive equity incentive is more significant when the environmental uncertainty is low, while the effect of employee stock ownership plan is more significant when the environmental uncertainty is high. 3) The equity incentive of state-owned listed companies cannot significantly improve enterprise performance when the environmental uncertainty is high. 4) High-quality external audit can significantly improve the effect of equity incentive on enterprise performance, and the effect is more obvious when the environmental uncertainty is high. The research conclusion confirms the necessity of reasonably selecting equity incentive objects under the influence of environmental uncertainty and also provides a useful reference for optimizing the reform of equity incentive system of state-owned enterprises and perfecting the external audit system.
Research progress of exosomes in orthopedics
Authors: Zhang Liang , Lin Yi , Zhang Xiannan , Shan Chen
Published: August 2022

Exosomes are nano-extracellular vesicles secreted by a variety of cells. They are composed of a double-layer membrane that can transport a variety of proteins, coding and non-coding genes, and bioactive substances. Exosomes participate in information transmission between cells and regulate processes such as cell proliferation, migration, angiogenesis, and phenotypic transformation. They have broad prospects in the occurrence, development, and treatment of many diseases including orthopedics. Exosomes derived from different types of bone cells such as mesenchymal stem cells, osteoblasts, osteoclasts, and their precursors are recognized to play pivotal roles in bone remodeling processes including osteogenesis, osteoclastogenesis, and angiogenesis. This articlesummarizes the characteristics of exosomes and their research progress in bone remodeling, bone tumors, vascular skeletal muscle injury, spinal cord injury, degenerative disc diseases, cartilage degeneration, osteoarthritis, necrosis of the femoral head, and osteoporosis.
A prognostic exosome-related LncRNA risk model correlates with the immune microenvironment in liver cancer
Authors: Su Duntao , Zhang Zeyu , Xu Zhijie , Xia Fada , Yan Yuanliang
Published: August 2022

Background: Emerging studies have shown the important roles of long noncoding RNAs (lncRNAs) in the occurrence and development of liver cancer. However, the exosome-related lncRNA signature in liver cancer remains to be clarified.

Methods: We obtained 371 tumor specimens and 50 normal tissues from the TCGA database. These samples were randomly divided into the training queue and verification queue. The exosome-related lncRNA risk model was verified by correlation analysis, Lasso regression analysis, and Cox regression analysis. The differences in the immune microenvironment in the two risk groups were obtained by analyzing the infiltration of different immune cells.

Results: Five exosome-related lncRNAs associated (MKLN1-AS, TMCC1-AS1, AL031985.3, LINC01138, AC099850.3) with a poor prognosis were identified and used to construct the signature. Receiver operating curve (ROC) and survival curves were used to confirm the predictive ability of this signature. Based on multivariate regression analysis in the training cohort (HR: 3.033, 95% CI: 1.762–5.220) and validation cohort (HR: 1.998, 95% CI: 1.065–3.751), the risk score was found to be an independent risk factor for patient prognosis. Subsequently, a nomogram was constructed to predict the 1-, 3-, 5-years survival rates of liver cancer patients. Moreover, this signature was also related to overexpressed immune checkpoints (PD-1, B7-H3, VSIR, PD-L1, LAG3, TIGIT and CTLA4).

Conclusion: Our study showed that exosome-related lncRNAs and the corresponding nomogram could be used as a better index to predict the outcome and immune regulation of liver cancer patients. This signature might provide a new idea for the immunotherapy of liver cancer in the future.
Evaluating the implementation quality of a vocational education intervention for youth in Dadaab refugee camp in Kenya: Evidence of discrimination
Authors: Kunyu David K. , Moreno Herrera Lázaro , Juang Linda P.
Published: August 2022

Refugee youth in protracted humanitarian contexts are faced with limited access to quality education. They may sustain traumatic experiences from conflicts and discrimination yet have limited psychosocial support access. Comprehending the magnitude and effects of these challenges is vital for designing and executing educational interventions in such contexts. This study evaluates the implementation quality of the Youth Education Pack intervention through the lens of the Inter-agency Network for Education in Emergencies minimum standards framework. It explores the types of discrimination experienced by refugee youth in the Dadaab refugee camp in Kenya. Nine participants comprising refugee students (N = 2), former refugee students (N = 2), teachers (N = 3), and project supervisors (N = 2) participated in the study. The first author conducted interviews and observations in the camp. The data were qualitatively coded deductively and analysed in Nvivo 12. We found that the YEP intervention faced contextual challenges that hindered the achievement of the implementation quality standards outlined in the INEE minimum standards for education. Refugee youth and refugee teachers experienced various forms of discrimination, including at individual, institutional, and structural levels. We conclude that providing refugee youth with an inclusive and high-quality education is central to providing secure and long-term solutions to their challenges and adversities and may promote their psychosocial wellbeing.