bluuebunny/crossref_metadata_2025 huggingface dataset:
Allowable Pillar Width for Salt Cavern Gas Storage Based on Triangular Well Layout: A Case Study in China
Authors: Cai Rui , Ma Hongling , Liang Xiaopeng , Zhao Kai , Yang Chunhe
Published: January 2024

Salt rock, renowned for its remarkable energy storage capabilities, exists in deep underground environments characterized by high temperature and pressure. It possesses advantageous properties such as high deformability, low permeability, and self-healing from damage. When establishing a cluster of salt cavern gas storage facilities, the careful selection of ore column widths between these reservoirs is crucial for minimizing the risk of structural failure, optimizing salt rock resource utilization, and enhancing the construction and operation of gas storage reservoirs. In current practices, square triangular arrangements are commonly used in designing well layouts for reservoir groups to balance stability and economic considerations. This study, conducted in the context of the Jintan salt cavern gas storage project in Jiangsu Province, employed FLAC3D to create a finite element model for proposed gas storage configurations. A comprehensive analysis of the long-term operational safety of salt cavern gas storage with triangular well layouts was carried out. Various indices were examined, covering aspects such as cavern wall displacement, characteristics of the plastic zone, volume shrinkage, safety coefficients, seepage range, pore pressure fluctuations, and seepage volume. The study also considered the mechanical behavior of hexagonal columns within the surrounding rock during extended storage operations, leading to the optimization of allowable widths for these columns. The results indicate that, at operating pressures ranging from 6.5 to 17 MPa, the permissible column width should exceed 1.67 times the maximum cavern diameter to ensure compliance with criteria for long-term stability and containment within a square triangular layout. These findings provide valuable insights into determining the optimal allowable widths of salt cavern columns for positive triangular layouts.
Fast Analytic–Numerical Algorithms for Calculating Mutual and Self-Inductances of Air Coils
Authors: Palka Ryszard
Published: January 2024

This paper deals with a method of calculating the mutual and self-inductances of various air coils located arbitrarily in space. Known elementary solutions (the Biot–Savart formulas) were used to determine the magnetic field of infinitely thin current loops and infinitely thin wires of finite length magnetically linking other coils. Unlike commonly used algorithms, these elementary solutions were not extensively transformed analytically but were used to perform calculations via direct numerical integration. This enabled the very quick and accurate obtaining of the self-inductance values, as well as determining the dependence of mutual inductances on the positions of both coils. This method allows for the analysis of different coil configurations (misaligned coils, inclined to each other, etc.) that other methods do not cover. It also enables the determination of the forces acting on the coils, as well as the calculation of the magnetic field distribution from any coil configuration. The obtained results were compared with those presented by other authors (both computational and measurement results).
IoT-Based Indoor Thermal Environment and Occupancy Monitoring for Energy Poverty Care
Authors: Yun Woo-Seung , Ryu Wontaek , Seo Hyuncheol , Hong Won-hwa , Lee Seung-Woo
Published: January 2024

Energy poverty, defined as difficulty meeting the minimum requirements for a thermal environment, is becoming a significant social issue. To provide efficient welfare services, information provision and monitoring are required. However, characteristics of energy poverty, such as inconsistent residential patterns, small living spaces, and limited electricity and telecommunication resources, lead to a lack of information. This research introduces the empirical results of the development of the system. Based on the feedback from welfare workers and experts supporting energy poverty, a monitoring system combining various sensors was prototyped. This system measures temperature, humidity, illuminance, air velocity, CO2, black bulb temperature, occupancy, and noise and generates indicators for occupancy and thermal environment monitoring. Applicability assessment was conducted across 55 energy poverty households in Korea during the duration of cooling and heating. Subjects were living in spaces averaging 6.3 sqm within buildings over 43 years old and renting on a monthly or weekly basis. Electricity and communication are partially supplied. Based on the actual measurement data and field surveys, the configuration of an energy poverty monitoring system was proposed. In particular, the applicability of the simple methodology for the determination of black bulb temperature, metabolic rate, and clothing insulation required for a thermal environment evaluation was assessed. The proposed system can be efficiently used for taking care of energy poverty where the installation of conventional monitoring systems is restricted.
Analytical Study of Permeability Properties of Loose Sandstone Based on Thermal-Hydraulic-Mechanical (THM) Coupling
Authors: Cui Rui , Feng Bo , Duan Xiaofei , Zhao Jichu , Yang Yabin , Feng Shoutao , Yuan Yilong
Published: January 2024

The permeability of reservoirs is a key factor affecting the exploitation and utilization of geothermal resources. This test used a core flow meter and other advanced experimental devices to investigate the evolution of the permeability characteristics of loose sandstone samples (with a diameter of 25 mm and a length of 50 mm) in the Zijiao Town area under various temperatures, confining pressures, injection rates, and cyclic loading and unloading conditions. The results show that (1) as the temperature increases, the overall trend of rock permeability decreases, which is mainly related to the thermal expansion of rock particles. In addition, the higher the temperature, the greater the gravel outflow. (2) The critical pressure for pore closure in the unconsolidated sandstone in the region is approximately 15 MPa. (3) The permeability change of loose sandstone under low injection rate conditions is relatively small and can be neglected. However, there is reason to believe that under high-flow injection conditions, the permeability of this type of rock mass will undergo significant changes. (4) Under the condition of loading and unloading, the permeability ratio curve of the unloading stage at three temperatures is almost a straight line. The higher the temperature, the smaller the slope, and the permeability at 20 °C with the highest recovery degree is only about 50% of the initial one.
Primary Frequency Regulation Strategy Based on Rotor Kinetic Energy of Double-Fed Induction Generator and Supercapacitor
Authors: Ma Renting , Yuan Shitong , Li Xianwei , Guan Shuying , Yan Xiangwu , Jia Jiaoxin
Published: January 2024

To address the challenge of wind turbines meeting primary frequency regulation requirements, incorporating energy storage devices to handle most of the frequency regulation tasks would result in increased operational costs. When a wind turbine rotor accelerates, it deviates from the maximum power tracking point (MPPT), leading to reduced output while retaining significant rotational kinetic energy. Based on this characteristic, a primary frequency regulation strategy is proposed that coordinates the rotor kinetic energy of a double-fed induction generator (DFIG) with supercapacitors (SCs). Supercapacitors provide power support during low-frequency conditions, while accelerating the wind turbine rotor reduces output during high-frequency conditions. Additionally, continuous attention is given to subsequent frequency changes. In case of short-term, low-frequency conditions, stored kinetic energy is released for power support, establishing a mechanism for wind turbine kinetic energy recovery and release. This mechanism reduces charging and discharging requirements for supercapacitors, extends their service life, and considers both wind turbine frequency regulation requirements and economy. Finally, using MATLAB 2020/Simulink platform allows for the verification of the effectiveness and rationality of this proposed method.
Enhancing Efficiency and Reliability of Tidal Stream Energy Conversion through Swept-Blade Design
Authors: Zheng Yangyang , Yang Wenxian , Wei Kexiang , Chen Yanling , Zou Hongxiang
Published: January 2024

The current limited efficiency and reliability of tidal current turbines (TCTs) have posed significant challenges in effectively harnessing tidal stream energy. To address this issue, this paper undertakes both numerical and experimental studies to explore the advantages of swept blades over conventional straight blades in terms of energy capture efficiency and cavitation resistance. It is found that both the sweep length and sweep angle of the blade can influence the power generation efficiency of the TCT. For the particular swept blade investigated in this study, the highest power coefficient is achieved when the sweep length is 0.544 m and the sweep angle is 28.88°. The research also demonstrated that the swept-blade TCT shows a higher power generation efficiency than the straight-blade TCT across a broad range of rotor speeds. To be precise, with the swept blades, the power coefficient of the TCT can be improved by 5–17%, depending on the tip speed ratio. Additionally, swept blades exhibit a superior cavitation resistance. This is evidenced by their higher cavitation numbers across all tip speed ratios in comparison to conventional straight blades.
Application of Hydrodynamic Cavitation in the Disintegration of Aerobic Granular Sludge—Evaluation of Pretreatment Time on Biomass Properties, Anaerobic Digestion Efficiency and Energy Balance
Authors: Zieliński Marcin , Dębowski Marcin , Kazimierowicz Joanna , Nowicka Anna , Dudek Magda
Published: January 2024

The use of aerobic granular sludge is a promising and future-proof solution for wastewater treatment. The implementation of this technology requires the development of efficient and cost-effective methods for the management of excess sludge. The aim of the research was to evaluate the effects of hydrodynamic cavitation on the efficiency of aerobic granular sludge digestion. Respirometric measurements were performed at a temperature of 38 °C and an initial organic load of 5.0 gVS/L. The changes in the properties of the pretreated biomass, the kinetics of methane fermentation, the amount and composition of the biogas produced, and an energetic evaluation of the process were carried out. A significant influence of hydrodynamic cavitation on the transfer of organic compounds into the dissolved phase was demonstrated. The degree of solubilisation was 37% for COD and 42% and for TOC. The efficiency of CH4 production from the pretreated sludge reached a value of 496 ± 12 mL/gVS, which corresponds to an increase of 19.6% compared to the raw biomass. The influence of cavitation on the CH4 content of the biogas was not observed. Strong correlations were found between the efficiency of anaerobic digestion and the concentration of dissolved organic compounds and the hydrodynamic cavitation time used. The gross energy yield was closely correlated with the amount of CH4. The highest comparable values of 3.12 Wh/gTS to 3.18 Wh/gTS were found in the variants in which the hydrodynamic cavitation (HC) time was between 15 min and 50 min. The highest net energy production of 2890 kWh/MgTS was achieved after 15 min of pretreatment.
NOx Emission Prediction for Heavy-Duty Diesel Vehicles Based on Improved GWO-BP Neural Network
Authors: Wang Zhihong , Feng Kai
Published: January 2024

NOx is one of the main sources of pollutants for motor vehicles. Nowadays, many diesel vehicle manufacturers may use emission-cheating equipment to make the vehicles meet compliance standards during emission tests, but the emissions will exceed the standards during actual driving. In order to strengthen the supervision of diesel vehicles for emission monitoring, this article intends to establish a model that can predict the transient emission characteristics of heavy-duty diesel vehicles and provide a solution for remote online monitoring of diesel vehicles. This paper refers to the heavy-duty vehicle National VI emission regulations and uses vehicle-mounted portable emission testing equipment (PEMS) to conduct actual road emission tests on a certain country’s VI heavy-duty diesel vehicles. Then, it proposes a new feature engineering processing method that uses gray correlation analysis and principal component analysis to eliminate invalid data and reduce the dimensionality of the aligned data, which facilitates the rapid convergence of the model during the training process. Then, a double-hidden-layer BP (Back propagation) neural network was established, and the improved gray wolf algorithm was used to optimize the threshold and weight of the neural network, and a heavy-duty diesel vehicle NOx emission prediction model was obtained. Through the training of the network, the root mean square error (RMSE) of the improved model on the test set between the predicted value and the true value is 1.9144 (mg/s), and the coefficient of determination (R2) is 0.87024. Compared with single-hidden-layer network and double-hidden-layer BP neural network models, the accuracy of the model has been improved. The model can well predict the actual road NOx emissions of heavy-duty diesel vehicles.
Effect of Lactic Acid Bacteria Fermentation on Plant-Based Products
Authors: Yang Xiaohua , Hong Jiaqi , Wang Linhao , Cai Changyu , Mo Huanping , Wang Jie , Fang Xiang , Liao Zhenlin
Published: January 2024

Lactic acid bacteria effectively utilize the nutrients and active compounds in plant-based materials via their powerful metabolic pathways and enzyme systems, achieving a combination of nutrition, functionality, and deliciousness. Currently, the majority of review articles predominantly concentrate on summarizing the fermentation of fruits and vegetables by lactic acid bacteria, devoting comparatively less attention to researching other plant species varieties and plant-based by-products. Furthermore, the summary of the research on the active substances and functional properties lacks sufficient depth. This review provides a comprehensive overview of the status of and technological progress in lactic acid bacteria fermentation of various plant species and plant-based by-products, and the effects of lactic acid bacteria on the active substances and functional properties are emphasized. In addition, this review emphasizes that active substances give products more functionality. The aim of this review is to emphasize the significant contribution of lactic acid bacteria to the active substances and functional properties of plant-based products, which will assist researchers in better comprehending the application value of lactic acid bacteria in the plant-based domain and direct attention towards the interaction mechanisms between active substances and product functionality. Concurrently, this review provides a certain theoretical foundation and reference for the application of fermented functional products in promoting health and preventing diseases.
Flexural Behavior of Pultruded GFRP–Concrete Composite Beams Strengthened with GFRP Stiffeners
Authors: Ali Muataz I. , Allawi Abbas A. , El-Zohairy Ayman
Published: January 2024

The utilization and incorporation of glass fiber-reinforced plastics (GFRP) in structural applications and architectural constructions are progressively gaining prominence. Therefore, this paper experimentally and numerically investigates the use of GFRP I-beams in conjunction with concrete slabs to form composite beams. The experimental design incorporated 2600 mm long GFRP I-beams which were connected compositely to concrete slabs with a 500 mm width and 80 mm thickness. The concrete slabs are categorized into two groups: concrete slabs cast using normal-strength concrete (NSC), and concrete slabs prepared using high-strength concrete (HSC). Various parameters like the type of concrete (normal and high-strength concrete), type of stiffeners bonded to the composite section (bolt–epoxy or bolt only), and inclusion of corrugated metal sheets were investigated. To obtain the full shear connection between the GFRP I-sections and concrete slabs, two rows of shear connectors in the form of bolts were utilized. These shear connectors were erected to the top flange of the GFRP I-sections to compositely connect between the GFRP I-beams and the concrete slabs as well as the corrugated metal sheets. The strengthening of the shear webs of GFRP I-beams with GFRP T-section stiffeners resulted in an enhancement in the flexural and shear strength. The failure loads in the case of the bolt–epoxy connection for the stiffeners were 8.2% and 10.0% higher than those in the case of bolt only when the concrete compressive strengths were 20.1 MPa and 52.3 MPa, respectively. Moreover, the effect of the concrete compressive strength was vital where the failure loads increased by 79.9% and 77.1% when HSC was used instead of NSC for the cases of bolt–epoxy and bolt only, respectively. The epoxy adhesive used in conjunction with mechanical connectors, specifically bolts, resulted in sufficient composite action and delayed shear failure within the web of the GFRP beam. For the specimens with bolt–epoxy connection, strain levels in the concrete slabs were consistently higher than in the other specimens with bolts alone at the same loading level. The concrete slabs integrated with HSC registered strain levels that were 20.0% and 21.8% greater for bolt–epoxy and bolt-only connections, respectively, when compared to those using normal-strength concrete (NSC). This discrepancy can likely be credited to the enhanced composite interaction between the concrete slabs and the GFRP I-beams. In addition, ABAQUS software (version 6.2) was used to develop FE models to analyze the tested composite beams and provide a parametric study using the verified models.
Comparison of the Correlations of Microbial Community and Volatile Compounds between Pit-Mud and Fermented Grains of Compound-Flavor Baijiu
Authors: Cheng Wei , Chen Xuefeng , Xue Xijia , Lan Wei , Zeng Huawei , Li Ruilong , Pan Tianquan , Li Na , Gong Zilu , Yang Hongwen
Published: January 2024

The microbial composition and volatile components of fermented grains (FG) and pit mud (PM) are crucial for the quality and flavor of compound-flavor baijiu (CFB). The physicochemical indices, culturable microorganisms, microbial communities, and volatile components of FG and PM were analyzed and correlated in our research. Considering FG and PM, amplicon sequencing was used to analyze the microbial community and the volatile components were detected by headspace solid-phase microextraction-gas chromatography–mass spectrometry (HS-SPME). For FG, redundancy analysis and correlation perfume Circos were used to clarify the correlations between the dominant microbial community and volatile components. The results showed that Aspergillus, Pichia, and Rhizopus were the main fungal microflora in FG and PM, whereas Lactobacillus and Bacillus were the dominant bacteria in FG, and Methanosarcina and Clostridium sensu stricto 12 were the dominant bacteria in the PM. The microbial community and volatile compounds in the CB sampled from the bottom layers of the FG were greatly affected by those in the PM. There were 32 common volatile components in CB and PM. For FG, most of the volatile components were highly correlated with Lactobacillus, Bacillus, Aspergillus, Pichia, and Monascus, which includes alcohols, acids and esters. This study reveals correlations between microbial composition, volatile components, and the interplay of FG and PM, which are conducive to optimizing the fermentation process and improving the quality of CFB base.
Effect of a Probiotic Beverage Enriched with Cricket Proteins on the Gut Microbiota: Composition of Gut and Correlation with Nutritional Parameters
Authors: Dridi Chaima , Millette Mathieu , Salmieri Stephane , Aguilar Uscanga Blanca R. , Lacroix Sebastien , Venneri Tommaso , Sarmast Elham , Allahdad Zahra , Di Marzo Vincenzo , Silvestri Cristoforo , Lacroix Monique
Published: January 2024

The health and balance of the gut microbiota are known to be linked to diet composition and source, with fermented products and dietary proteins potentially providing an exceptional advantage for the gut. The purpose of this study was to evaluate the effect of protein hydrolysis, using a probiotic beverage enriched with either cricket protein (CP) or cricket protein hydrolysates (CP.Hs), on the composition of the gut microbiota of rats. Taxonomic characterization of the gut microbiota in fecal samples was carried out after a 14-day nutritional study to identify modifications induced by a CP- and CP.H-enriched fermented probiotic product. The results showed no significant differences (p > 0.05) in the diversity and richness of the gut microbiota among the groups fed with casein (positive control), CP-enriched, and fermented CP.H-enriched probiotic beverages; however, the overall composition of the microbiota was altered, with significant modifications in the relative abundance of several bacterial families and genera. In addition, fermented CP.H-enriched probiotic beverages could be related to the decrease in the number of potential pathogens such as Enterococcaceae. The association of gut microbiota with the nutritional parameters was determined and the results showed that digestibility and the protein efficiency ratio (PER) were highly associated with the abundance of several taxa.
Multistability Mechanisms for Improving the Performance of a Piezoelectric Energy Harvester with Geometric Nonlinearities
Authors: Wang Zhenhua , Shang Huilin
Published: January 2024

This study presents multistability mechanisms that can enhance the energy harvesting performance of a piezoelectric energy harvester (PEH) with geometrical nonlinearities. To configure triple potential wells, static bifurcation diagrams in the structural parameter plane are depicted. On this basis, the key structural parameter is considered, of which three reasonable values are then chosen for comparing and evaluating the performances of the triple-well PEH under them. Then, intra-well responses and the corresponding voltages of the system are investigated qualitatively. A preliminary analysis of the suitable energy-harvesting conditions is carried out, which is then validated by numerical simulations of the evolution of coexisting attractors and their basins of attraction with variations in the excitation level and frequency. It follows that, under a low-level ambient excitation, the intra-well responses around the trivial equilibrium dominate the energy-harvesting performance. When the level of the environmental excitation is very low, which one of the three values of the key structural parameter is the best for improving the performance of the PEH system depends on the range of the excitation frequency; when the excitation level increases sufficiently to induce inter-well responses, the maximum one is the best for improving the performance of the PEH. The findings provide valuable insights for researchers working in the structure optimization and practical applications of geometrically nonlinear PEHs.
Chitosan–Polyethylene Glycol Inspired Polyelectrolyte Complex Hydrogel Templates Favoring NEO-Tissue Formation for Cardiac Tissue Engineering
Authors: Keklikian Angelo , de Barros Natan Roberto , Rashad Ahmad , Chen Yiqing , Tan Jinrui , Sheng Ruoyu , Sun Dongwei , Liu Huinan , Thankam Finosh G.
Published: January 2024

Neo-tissue formation and host tissue regeneration determine the success of cardiac tissue engineering where functional hydrogel scaffolds act as cardiac (extracellular matrix) ECM mimic. Translationally, the hydrogel templates promoting neo-cardiac tissue formation are currently limited; however, they are highly demanding in cardiac tissue engineering. The current study focused on the development of a panel of four chitosan-based polyelectrolyte hydrogels as cardiac scaffolds facilitating neo-cardiac tissue formation to promote cardiac regeneration. Chitosan-PEG (CP), gelatin-chitosan-PEG (GCP), hyaluronic acid-chitosan-PEG (HACP), and combined CP (CoCP) polyelectrolyte hydrogels were engineered by solvent casting and assessed for physiochemical, thermal, electrical, biodegradable, mechanical, and biological properties. The CP, GCP, HACP, and CoCP hydrogels exhibited excellent porosity (4.24 ± 0.18, 13.089 ± 1.13, 12.53 ± 1.30 and 15.88 ± 1.10 for CP, GCP, HACP and CoCP, respectively), water profile, mechanical strength, and amphiphilicity suitable for cardiac tissue engineering. The hydrogels were hemocompatible as evident from the negligible hemolysis and RBC aggregation and increased adsorption of plasma albumin. The hydrogels were cytocompatible as evident from the increased viability by MTT (>94% for all the four hydrogels) assay and direct contact assay. Also, the hydrogels supported the adhesion, growth, spreading, and proliferation of H9c2 cells as unveiled by rhodamine staining. The hydrogels promoted neo-tissue formation that was proven using rat and swine myocardial tissue explant culture. Compared to GCP and CoCP, CP and HACP were superior owing to the cell viability, hemocompatibility, and conductance, resulting in the highest degree of cytoskeletal organization and neo-tissue formation. The physiochemical and biological performance of these hydrogels supported neo-cardiac tissue formation. Overall, the CP, GCP, HACP, and CoCP hydrogel systems promise novel translational opportunities in regenerative cardiology.
Functional Gels and Chemicals Used in Oil and Gas Drilling Engineering: A Status and Prospective
Authors: Yang Keqing , Bai Yingrui , Ma Jiayun , Sun Jinsheng , Liu Yuan , Lang Youming
Published: January 2024

Research into functional gels and chemicals and their applications represents a cutting-edge international field of study. For example, investigating how they can be applied in oil and gas drilling (and extraction engineering) and developing novel functional chemical materials for the oil field could provide innovative solutions and technological methods for oil and gas drilling and extraction operations. Through a literature analysis, this paper presents a review of the current research status and application scenarios of different types of functional gels and chemicals, both domestically and internationally. The classification and preparation principles of various functional materials are systematically outlined and the current applications of functional gels and chemicals in oil and gas drilling and extraction engineering are introduced. These applications include drilling and plugging, enhanced oil recovery, water plugging, and profile control. The formation mechanisms and application scenarios of different types of gels and chemicals are also analyzed and summarized, with a discussion of their prospects in oil and gas drilling and extraction engineering. We broaden the scope of functional gels and chemicals by exploring new application fields and promoting the development of different types of gels and chemicals in a more intelligent direction.
U-Pb Dating of the Kolchugino Group Basement (Kuznetsk Coal Basin, Siberia): Was the Change in Early–Middle Permian Floras Simultaneous at Different Latitudes in Angaraland?
Authors: Silantiev Vladimir V. , Gutak Yaroslav M. , Tichomirowa Marion , Käßner Alexandra , Kutygin Ruslan V. , Porokhovnichenko Lyubov G. , Karasev Eugeny V. , Felker Anastasia S. , Bakaev Aleksandr S. , Naumcheva Maria A. , Urazaeva Milyausha N. , Zharinova Veronika V.
Published: January 2024

The Kuznetsk Basin (Kuzbass) is one of the largest coal basins in Siberia and a reference area for the ancient Angaraland continent. The proximity of the Kuzbass and Siberian Platform caused their biotic similarities in the Late Palaeozoic. However, due to biota endemism, the Kuzbass Upper Palaeozoic does not correlate directly with the International Chronostratigraphic Chart (ICC). This paper discusses radioisotopic (CA-ID-TIMS) dating of zircons from a volcanic tuff located in the Starokuznetsk Formation (Fm). This level matches the interval of the Balakhonka/Kolchugino (B/K) floral change in Kuzbass, i.e., the gradual replacement of cordaitoid-dominated wet forests (Balakhonka flora) with more arid fern–pteridosperm–cordaitoid assemblages (Kolchugino flora). New age (276.9 ± 0.4 Ma) directly correlates the Starokuznetsk Fm with the Upper Kungurian of the ICC. We compared the Kuzbass data with data of the Western Verkhoyanie, where Middle Permian ammonoids (Sverdrupites assemblage) occur in strata recording the B/K floral change. The available (ICC) and new datings indicate the lag between the B/K floral change in low (Kuzbass) and high (Verkhoyanie) latitudes of Angaraland. The B/K floral change in the Kuzbass began in the early Late Kungurian and was completed by the end of this age. In contrast, the B/K floral change in Verkhoyanie began at the end of the Late Kungurian and was completed in the Late Wordian. The delay in the floral changes at different latitudes of Angaraland suggests that existing interregional correlations need further improvement.
A Thousand Concepts and the Participating Body: Concept Play Workshops at Kunsthall 3,14
Authors: Kukkonen Heidi Marjaana
Published: January 2024

Participation has become the keyword in museum and gallery education during the past decades. However, the focus on participation might contain neoliberalist tendencies, creating more entertainment and consumerism than art. In this study based on practice-based research, I explore a gallery educational method to mediate contemporary art to primary and high school students inspired by Gilles Deleuze and Félix Guattari’s process philosophy and new materialist theory–practice. What kind of roles can the method of Concept Play Workshop create for the participating body and how can it challenge neoliberal tendencies in museum and gallery education? In the workshops, children and young people create philosophical concepts with contemporary art, dialogue-based practices and artistic experiments in the exhibition space of Kunsthall 3,14 in Bergen, Norway. I argue that the method can create philosophizing, critical, uncomfortable, resting, dictatorial and protesting bodies. Representational logic becomes challenged, and discomfort and resistance become educational potential. The method creates multiple and overlapping roles for the participating body, shifting the focus towards multiplicities instead of the passive/active binary. Humans are not the only participating bodies, but attention is given to agential matter, contesting human-centeredness. The study is a contribution to the field of post-approaches in gallery and museum education.
Setting Up a Just and Fair ICU Triage Process during a Pandemic: A Systematic Review
Authors: Chakraborty Rhyddhi , Achour Nebil
Published: January 2024

Introduction: Triage is a dynamic and complex decision-making process to determine fair access to medical care in mass casualty situations. Triage takes place through healthcare settings including Intensive Care Units (ICUs). Triage governing principles have been subject to ethical debates for a long time specifically with the recent global pandemic of COVID-19. This study aims to revisit the ethical principles guiding patient prioritisation during recent COVID-19 disaster triage in the Indian subcontinent and attempts to look for principles with consideration of social justice. Methods: Key electronic databases such as WHO, EMBASE, and DOAJ were used to access published literature relating to ICU triage in the Indian subcontinent. Literature on and from 2015–2022 were included in this study. The SPICE framework was used to identify the literature. The Inclusion criteria were as follows: Literature with ethical connotations focusing on India and neighbouring countries, and in an ICU setting during pandemics. The Exclusion criteria were as follows: Literature focusing on other countries, without ethical foundations, hospital admissions, and non-COVID-19 ICU admissions. The PRISMA standard was applied to screen the appropriate literature. The BOOLEAN operator “OR” was used to enhance the literature search. Finally, six papers were found suitable for this study and thus were included in the literature review. Additionally, for the second time, the frequency of certain ethical phrases was reassessed in the plans and guidelines to check the changed awareness of ethical pandemic planning, if any. A thematic analysis was applied to analyse the data and generate findings and new knowledge. Results: The findings highlight gaps in knowledge around ICU triaging in the region which indicates the scope of better ethical pandemic preparation at the regional level. The findings show that there is a debate between researchers on prioritisation from available resources and ethical perspectives and principles associated with fair access to healthcare even during pandemic times. The literature also highlights enhancing the regional capacity and building equitable approaches to reduce existing health inequities and the need of the social justice framework for ICU triaging during a pandemic. Conclusions: ICU triaging in five South Asian neighbour nations was studied for the presence of a guided ethical framework. Additionally, for the second time, certain ethical phrases were reassessed in the plans and guidelines; however, usage of those terms was found to be significantly low. The discussion shows that the plans and guidelines have the scope to improve ethical ICU triaging in these countries and in the specific region. After analysing different ethical guidelines, this study emphasises that there is a need for a just and fair framework, specifically a social justice framework in ICU triage in the subcontinent to address the underlying health inequities.
A Review of Current Perspectives on Motoric Insufficiency Rehabilitation following Pediatric Stroke
Authors: Colovic Hristina , Zlatanovic Dragan , Zivkovic Vesna , Jankovic Milena , Radosavljevic Natasa , Ducic Sinisa , Ducic Jovan , Stojkovic Jasna , Jovanovic Kristina , Nikolic Dejan
Published: January 2024

Pediatric stroke (PS) is an injury caused by the occlusion or rupture of a blood vessel in the central nervous system (CNS) of children, before or after birth. Hemiparesis is the most common motoric deficit associated with PS in children. Therefore, it is important to emphasize that PS is a significant challenge for rehabilitation, especially since the consequences may also appear during the child’s growth and development, reducing functional capacity. The plasticity of the child’s CNS is an important predecessor of recovery, but disruption of the neural network, specific to an immature brain, can have harmful and potentially devastating consequences. In this review, we summarize the complexity of the consequences associated with PS and the possibilities and role of modern rehabilitation. An analysis of the current literature reveals that Constraint-Induced Movement Therapy, forced-use therapy, repetitive transcranial magnetic stimulation, functional electrical stimulation and robot-assisted therapy have demonstrated at least partial improvements in motor domains related to hemiparesis or hemiplegia caused by PS, but they are supported with different levels of evidence. Due to the lack of randomized controlled studies, the optimal rehabilitation treatment is still debatable, and therefore, most recommendations are primarily based on expert consensuses, opinions and an insufficient level of evidence.
The Effectiveness of Teaching the Teacher Interventions in Improving the Physical Activity among Adolescents in Schools: A Scoping Review
Authors: Christodoulakis Antonios , Bouloukaki Izolde , Aravantinou-Karlatou Antonia , Margetaki Katerina , Zografakis-Sfakianakis Michail , Tsiligianni Ioanna
Published: January 2024

Physical inactivity is a leading risk factor for global mortality as it increases the risk of non-communicable diseases and decreases overall health. Therefore, increasing physical activity (PA) is strongly recommended, particularly in adolescents. The Teaching the Teachers (TTT) approach is a prominent example of an intervention that could enhance PA levels in adolescents. However, available evidence on the efficacy of TTT interventions in promoting PA among adolescents is either limited or inconclusive. Therefore, a scoping review was conducted to provide an overview of the current state of knowledge regarding the effectiveness of TTT interventions in improving the PA of adolescent students. The PRISMA-Scoping methodology was employed, and articles in the Medline database were searched. We screened 2357 articles for inclusion, and finally included 16 articles. Most articles were conducted in European countries. The TTT interventions appeared to positively affect various aspects of PA. These aspects include support for personal autonomy, intent to engage in PA, improvements in body composition and fitness level, social support, enjoyment of Physical Education (PE), and positive attitudes towards PE. Consequently, policymakers could utilize TTT interventions to improve the physical activity of adolescents, which may reduce the burden of non-communicable diseases and foster healthier societies.
Factors Associated with Lifestyle Behaviors among University Students—A Cross-Sectional Study
Authors: Alothman Shaima A. , Al Baiz Alia Abdulaziz , Alzaben Abeer Salman , Khan Ruqaiyah , Alamri Ali Faris , Omer Asma B.
Published: January 2024

Lifestyle behaviors are daily habits influenced by social and environmental factors. This study examined lifestyle behaviors and their associations with sociodemographics, comorbidities, and pain in Saudi university students during the academic year 2021 and 2022. All students received the study invitation via university emails to complete an online questionnaire. The questionnaire included four sections (sociodemographics, health-related information, desired health promotion activities, and a lifestyle behavior assessment) via Health-Promoting Lifestyle Profile II (HPLP-II). The associations between study variables were assessed using Pearson’s correlation and multiple linear regression. The study questionnaire was completed by 1112 students. No correlation was found between sociodemographics and lifestyle-behavior-related factors except for students in the College of Science who appeared to have good lifestyle behaviors (an increase in HPLP II total scores of 3.69). Students with mental health issues have poorer lifestyle behaviors and spend more time sitting (p < 0.00). Students without disabilities have lower scores in health responsibility, physical activity, nutrition, and stress management, while auditory disability specifically lowers health responsibility (p < 0.00). Pain was not associated with any assessed lifestyle behaviors. This study identified several significant correlations and differences between variables such as age, sedentary behavior, sleep duration, disability status, college major, and lifestyle behaviors among PNU students. These findings provide insights into the factors that influence students’ health-promoting behaviors and can help guide interventions for promoting healthier lifestyles on campus. Targeted health promotion strategies at an early age could help in decreasing overall noncommunicable disease incidents later in life. The study results should be interpreted taking into consideration that the collected data were cross-sectional and self-reported. In conclusion, the findings of this study clearly demonstrate the need for specific lifestyle and health-promoting programs that are directed toward university students.
Assessing the Link between Nurses’ Proficiency and Situational Awareness in Neonatal Care Practice Using an Eye Tracker: An Observational Study Using a Simulator
Authors: Sugimoto Masahiro , Oyamada Michiko , Tomita Atsumi , Inada Chiharu , Sato Mitsue
Published: January 2024

Nurses are expected to depend on a wide variety of visually available pieces of patient information to understand situations. Thus, we assumed a relationship between nurses’ skills and their gaze trajectories. An observational study using a simulator was conducted to analyze gaze during neonatal care practice using eye tracking. We defined the face, thorax, and abdomen of the neonate, the timer, and the pulse oximeter as areas of interest (AOIs). We compared the eye trajectories for respiration and heart rate assessment between 7 experienced and 13 novice nurses. There were no statistically significant differences in the time spent on each AOI for breathing or heart rate confirmation. However, in novice nurses, we observed a significantly higher number of instances of gazing at the thorax and abdomen. The deviation in the number of instances of gazing at the face was also significantly higher among novice nurses. These results indicate that experienced and novice nurses differ in their gaze movements during situational awareness. These objective and quantitative differences in gaze trajectories may help to establish new educational tools for less experienced nurses.
Obtaining Spatial Variations in Cabernet Sauvignon (Vitis vinifera L.) Wine Flavonoid Composition and Aromatic Profiles by Studying Long-Term Plant Water Status in Hyper-Arid Seasons
Authors: Yu Runze , Torres Nazareth , Kurtural Sahap Kaan
Published: January 2024

The spatial variability in vineyard soil might negatively affect wine composition, leading to inhomogeneous flavonoid composition and aromatic profiles. In this study, we investigated the spatial variability in wine chemical composition in a Cabernet Sauvignon (Vitis vinifera L.) vineyard in 2019 and 2020. Because of the tight relationships with soil profiles, mid-day stem water potential integrals (Ψstem Int) were used to delineate the vineyard into two zones, including Zone 1 with relatively higher water stress and Zone 2 with relatively lower water stress. Wine from Zone 2 generally had more anthocyanins in 2019. In 2020, Zone 1 had more anthocyanins and flavonols. Zone 2 had more proanthocyanidin extension and terminal subunits as well as total proanthocyanidins in 2020. According to the Principal Component Analyses (PCA) for berry and wine chemical composition, the two zones were significantly different in the studied wine aromatic compounds. In conclusion, this study provides evidence of the possibility of managing the spatial variability of both wine flavonoid composition and aromatic profiles through connecting vineyard soil variability to grapevine season-long water status.
From Ocean to Medicine: Harnessing Seaweed’s Potential for Drug Development
Authors: Cotas João , Lomartire Silvia , Gonçalves Ana M. M. , Pereira Leonel
Published: January 2024

Seaweed, a miscellaneous group of marine algae, has long been recognized for its rich nutritional composition and bioactive compounds, being considered nutraceutical ingredient. This revision delves into the promising role of seaweed-derived nutrients as a beneficial resource for drug discovery and innovative product development. Seaweeds are abundant sources of essential vitamins, minerals, polysaccharides, polyphenols, and unique secondary metabolites, which reveal a wide range of biological activities. These bioactive compounds possess potential therapeutic properties, making them intriguing candidates for drug leads in various medical applications and pharmaceutical drug development. It explores their pharmacological properties, including antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, shedding light on their potential as therapeutic agents. Moreover, the manuscript provides insights into the development of formulation strategies and delivery systems to enhance the bioavailability and stability of seaweed-derived compounds. The manuscript also discusses the challenges and opportunities associated with the integration of seaweed-based nutrients into the pharmaceutical and nutraceutical industries. Regulatory considerations, sustainability, and scalability of sustainable seaweed sourcing and cultivation methods are addressed, emphasizing the need for a holistic approach in harnessing seaweed’s potential. This revision underscores the immense potential of seaweed-derived compounds as a valuable reservoir for drug leads and product development. By bridging the gap between marine biology, pharmacology, and product formulation, this research contributes to the critical advancement of sustainable and innovative solutions in the pharmaceutical and nutraceutical sectors.
Apoptotic Cell Death in an Animal Model of Virus-Induced Acute Liver Failure—Observations during Lagovirus europaeus/GI.2 Infection
Authors: Bębnowska Dominika , Hrynkiewicz Rafał , Rzeszotek Sylwia , Freus Marika , Poniewierska-Baran Agata , Niedźwiedzka-Rystwej Paulina
Published: January 2024

Lagovirus europaeus/GI.2 causes severe and highly fatal Rabbit Hemorrhagic Disease (RHD). Because of its characteristics, this infection is used as an animal model for acute liver failure (ALF). Apoptosis is one of the key processes underlying ALF and has been described as one of the mechanisms of RHD pathogenesis. Apoptotic cell death has been quite well characterized in infection with different variants of GI.1 strains, but so far, the GI.2 genotype has not been widely studied. In this study, we performed an evaluation of apoptotic cell death in hepatocytes of rabbits infected with Lagovirus europaeus/GI.2. We analyzed the expression of genes involved in apoptotic cell death by real-time PCR and performed immunohistochemical (IHC) assays. We showed a significant increase in the expression of caspase-3 and the proapoptotic Bax and anti-apoptotic Bcl-2 in infected animals. In addition, we recorded increased Bax/Bcl-2 ratios. IHC analyses showed the presence of morphological signs of apoptosis in the hepatocytes of infected rabbits. Our results indicate that caspase-3 and proteins from the Bcl-2 families play a key role in apoptosis induced by Lagovirus europaeus/GI.2 infection.
Novel Pitolisant-Derived Sulfonyl Compounds for Alzheimer Disease
Authors: Pérez-Silanes Silvia , Martisova Eva , Moreno Esther , Solas Maite , Plano Daniel , Sanmartin Carmen , Ramírez María Javier
Published: January 2024

Alzheimer’s disease (AD) is a complex and multifactorial neurodegenerative disorder characterized by cognitive decline, memory loss, behavioral changes, and other neurological symptoms. Considering the urgent need for new AD therapeutics, in the present study we designed, synthesized, and evaluated multitarget compounds structurally inspired by sulfonylureas and pitolisant with the aim of obtaining multitarget ligands for AD treatment. Due to the diversity of chemical scaffolds, a novel strategy has been adopted by merging into one structure moieties displaying H3R antagonism and acetylcholinesterase inhibition. Eight compounds, selected by their binding activity on H3R, showed a moderate ability to inhibit acetylcholinesterase activity in vitro, and two of the compounds (derivatives 2 and 7) were also capable of increasing acetylcholine release in vitro. Among the tested compounds, derivative 2 was identified and selected for further in vivo studies. Compound 2 was able to reverse scopolamine-induced cognitive deficits with results comparable to those of galantamine, a drug used in clinics for treating AD. In addition to its efficacy, this compound showed moderate BBB permeation in vitro. Altogether, these results point out that the fragment-like character of compound 2 leads to an optimal starting point for a plausible medicinal chemistry approach for this novel strategy.