bluuebunny/crossref_metadata_2025 huggingface dataset:
Real Value of Ukraine to the Contemporary Euro-Atlantic Space
Authors: Pyrozhkov Serhii , Khamitov Nazip
Published: December 2022

The article conceptualises the real value of Ukraine in the context of the contemporary Euro-Atlantic civilisational community. In this regard, it raises the question of the global criteria of victory of our country in the war with the neo-totalitarian ‘northern neighbour’. Those criteria simultaneously serve as the global purport and meaning of Ukraine’s victory for the world and drive the decisions of the Western countries on rendering economic and military aid. The underlying criterion of Ukraine’s victory is the preservation and development of civilisational agency of our country and the triumph of the new humanism over neo-totalitarianism, which today threatens not only our country but also the world as a whole. Facing neo-totalitarianism, the new humanism is not confined to compassion for the Other, but rather extends to consolidation and co-creativity with the Other.
Furthermore, the article highlights the Kyiv-Rus identity of Ukrainians, which consolidates the Ukrainian political nation, facilitating national resilience for the sake of the country’s agency. The Kyiv-Rus identity in its essence is juxtaposed against the muscovite-russian imperial identity at the level of values and further aligns Ukraine with the European identity. The author stresses that in addition to value-centred consolidation, Ukraine must also actively fulfil its interests in cooperation with the ‘Collective West’, given that shared interests among countries amid emergencies often prevail over values.
Keywords: Euro-Atlantic space, humanism, neo-totalitarianism, meta-anthropology, meta-anthropological potentialism, personalism, worldview tolerance, consolidation, identity, mentality, Kyiv-Rus identity, Kyiv-Rus mentality, civilisational agency of Ukraine.
Penerapan Metode Single Exponential Smoothing Untuk Prediksi Kasus Positif COVID 10 di Kabupaten Bengkalis
Authors: Mulyana Wide , Aryanto  , Aprilia Maudy
Published: December 2022

Pada bulan Desember 2019, penyebaran virus corona, juga dikenal sebagai SARS-CoV-2, secara resmi dinamai covid-19 oleh World Health Organization pertama kali muncul di Wuhan, Cina. Covid-19 saat ini merupakan ancaman yang sangat serius bagi kehidupan manusia di dunia. Prediksi adalah suatu proses memperkirakan secara sistematis tentang sesuatu yang paling mungkin terjadi di masa depan berdasarkan informasi masa lalu dan sekarang yang dimiliki, agar kesalahannya (selisih antara sesuatu yang terjadi dengan hasil perkiraan) dapat diperkecil. Metode Single Exponential Smoothing lebih cocok digunakan untuk memprediksi data yang fluktuasinya tidak stabil atau perubahannya besar dan bergejolak (Margi S & Pendawa W, 2015). Adapun indikator penentu tingkat penyimpangan atau error yang digunakan adalah Mean Squared Error (MSE). Kelebihan MSE adalah MSE merupakan standar error untuk menilai atau untuk mengetahui kesalahan dalam prediksi. Prinsip dalam menghitung kesalahan prediksi (forecast error), model yang baik adalah model yang mempunyai kesalahan error paling kecil dari terhadap data pengamatan yang sebenarnya di lapangan (Supriana dan Uci, 2010). Penelitian ini menggunakan metode Single Exponential Smoothing, pada proses perhitungan membutuhkan data kasus positif covid-19 di masa lalu dengan nilai alpha sebagai parameter pemulusan dan metode Mean Squared Error (MSE) untuk menentukan tingkat kesalahan prediksi.

Kata kunci: covid-19, prediksi, single exponential smoothing, MSE.
Geographical information sistem for mapping mosques in the village of Dayo Rokan Hulu District
Authors: Syahputra Aldi , Devara Muhammad Febri , Habibi Murtadho Habibi
Published: December 2022

Geographic Information Sistem (GIS) is a component consisting of hardware, software, human resources and data that work together effectively to enter, store, repair, update, manage, manipulate, integrate, analyze and display data in an information-based geographic [1]. This research was conducted to analyze the distribution of mosques and information about mosques in Dayo Village, Rokan Hulu District, Riau. The aim is to help the community, especially newcomers, to find maps of the distribution of mosques, routes to mosques, schedules for Friday prayer officers and other information that currently does not use a computerized sistem, which is an obstacle especially for the people in the Dayo Village area. The method used in data collection was by direct observation of mosques in Dayo Village and conducting interviews with mosque administrators and local residents, besides that a literature study was also carried out to find references to previous research. By using GIS, it is hoped that it will be easier for the community to find out the distribution of mosques in Dayo Village, the locations of the mosques along with the information available. All of this information can be easily accessed online via smartphones or other devices
Aplikasi pengenalan permainan tradisional nusantara (pandora) berbasis android
Authors: Mashudi Nurhadi , M. Mashudi  , Perty Putriani Saragih  , Praba Isna Tasya  , Triyani Arita Fitri
Published: December 2022

Nusantara adalah negara kepulauan yang terbentang luas dari pulau Sumatera hingga Papua yang merupakan bagian dari wilayah Indonesia. Indonesia yang merupakan negara akan kaya akan budaya. Salah satu budaya yang dimiliki Indonesia adalah budaya permainan tradisional nusantara. PANDORA merupakan aplikasi android yang memberikan informasi berbagai permainan tradisional di Indonesia dan dilengkapi dengan adanya fitur-fitur Tentang PANDORA. Tujuan penelitian ini adalah membangun aplikasi PANDORA (Permainan Tradisional Nusantara) sebagai sarana penanaman pendidikan karakter melalui pelestarian kebudayaan bangsa. Metode penelitian yang di gunakan adalah Extreme Programming (XP). Penelitian ini menghasil sebuah aplikasi yang berisikan fitur – fitur dan informasi yang dapat membantu masyarakat mendapatkan informasi permainan tradisional nusantara.
Sosyal Bilgiler Öğretmeni Adaylarının Keşif Temelli Sosyal Bilgiler Öğretimine İlişkin İnanç ve Deneyimleri
Authors: ÇULHA ÖZBAŞ Banu , KAYA İzel
Published: December 2022

Bu araştırmanın amacı, Sosyal Bilgiler öğretmeni adaylarının keşif temelli Sosyal Bilgiler öğretimine ilişkin inanç ve deneyimlerini derinlemesine incelemektir. Araştırma, nitel araştırma türlerinden çoklu durum çalışmasıyla tasarlanmıştır. Araştırmanın çalışma grubunu Türkiye’nin batı illerinden birinde Sosyal Bilgiler öğretmenliği lisans programına devam etmekte olan amaçlı örnekleme yoluyla belirlenen beş son sınıf Sosyal Bilgiler öğretmeni adayı oluşturmaktadır. Araştırmada veri toplama aracı olarak; yarı yapılandırılmış görüşme, öğretmen adaylarının keşif temelli Sosyal Bilgiler öğretimine ilişkin hazırladıkları iki ders planları, öğretmen adaylarının hazırladıkları ders planlarının uygulamasına ilişkin hatırlatıcılı görüşme ve son olarak yaşanan sürecin değerlendirilmesine ilişkin hazırlanan yarı yapılandırmış görüşme kullanılmıştır. Araştırmada birden fazla veri toplama yöntemi kullanılarak veri çeşitlemesine gidilmiştir. Öğretmen adaylarının araştırma kapsamında geliştirdikleri keşif temelli ders planları Keşif Temelli Sosyal Bilgiler Ders Planında yer alan basamaklara göre değerlendirilmiştir. Bu basamaklar: merak uyandıran sorunun belirlenmesi, sosyal bilim disiplinlerine ait kavramları ve araştırma yöntemlerini kullanarak keşfin derinleştirilmesi, kaynakların değerlendirilmesi ve kanıtların kullanılması, sonuçlara ulaşılması ve etkin vatandaşlık boyutunda bilgiye dayalı karar vermedir. Sosyal Bilgiler öğretmeni adaylarının keşif temelli ders planları incelendiğinde planı hazırlarken en çok “merak uyandıran soru sorma” ve “etkin vatandaşlık” basamağında zorlandıkları görülmüştür. Araştırma sonucunda Sosyal Bilgiler öğretmeni adaylarının ideal sınıf ortamının nasıl olması gerektiğine ilişkin inançlarının, öğrencileri ulusal sınavlara hazırlayabilme kaygılarının, öğretmenlik deneyimini yaşadıkları okul ikliminin Keşif Temelli Sosyal Bilgiler öğretimine ilişkin inançları üzerinde etkisi olduğu anlaşılmıştır. Araştırma sonunda bu sonuçlar doğrultusunda önerilerde bulunulmuştur.
Exploring Best Approaches to Bible Translation for Native and Non-Native English Speakers
Authors: Ogunlana Babatunde Adekunle
Published: December 2022

From around the Reformation period to modern times, many English Bibles have been produced. In their production, many approaches have been employed. These approaches have been categorized in different ways by different scholars. Two of these approaches have been identified and explained in this article. They are formal equivalence and functional equivalence. According to Bill Mounce, formal equivalence shows a strong preference for replicating the form of the original languages. It makes translations reflect the formal structure of the original text. E. Ray Clendenen and David K. Stabnow assert that functional equivalent translation aims primarily at a high degree of naturalness in the translation. It renders the original language in such a way that it sounds natural in the target language. These approaches have also given way to different types of translation and qualities of translation. There are two major types of translation. They are literal translation and meaning-based translation. There are some qualities that a good translation should attain. Some of these qualities are accuracy, clarity, naturalness and faithfulness to the source text. The questions of great importance that are begging for the answer are: What is the best approach to Bible translation? How can this approach be attained? This article examines the best approaches to Bible translation and explains how the Mobilized Assistance Supporting Translation (MAST) method can assist to maintain check and balance in the interaction of Biblical translation approaches. The English translations of the Bibles are used as illustrations. The article summarizes the best approach to Bible translation and posits that the English Bible produced is in-between the literal translation and meaning-based translation, natural, clear, accurate, and faithful to the source text. The study recommends that such an approach can be found when the MAST method is adopted, and the English Bible produced will be readable and familiar to both native English speakers and non-native English speakers.

Keywords – Bible Translation, Formal Equivalence, Functional Equivalence, MAST Methods
A Comparative Study of Word Orders in the Law Code of Hammurabi and the Book of Covenant
Authors: Ogunlana Babatunde Adekunle
Published: December 2022

The article examines how words are arranged in twenty-nine laws of the law code of Hammurabi and Exodus 21:2-22:16 through a comparative study to argue that these words are arranged to reflect Babylonian and Israelite theologies. The words are arranged in the Law Code of Hammurabi to reflect the distinction of social classes in Babylonian society. The awῑlum is rated highest, followed by muškênum and followed by wardum-amtum. As for the Book of the Covenant, the words are arranged to reflect the high value placed on human life in Israelite society. The laws do not discriminate in terms of social class. They express a great concern for the rights of the less privileged and encourage human good treatment. Thus, the conclusion is that there exists a relationship between the Book of the Covenant and the law code of Hammurabi and this relationship can be said to be moderate. The Book of the Covenant can be said to be a translation and adaptation of the law code of Hammurabi or any other ancient law code. Therefore, syntax is of great significance in the study of the ancient law codes because it helps to understand the content of these law codes. This article contributes to the study of the ancient law codes.

Key Words: The Book of the Covenant, The Law Code of Hammurabi, Word Order, Exodus 21:2-22:16
Diffuse pigmented villonodular synovitis of the knee joint: 3-year follow-up of a case report
Authors: Koutalos Antonios A. , Ragias Dimitrios , Rizniotopoulos Emmanouel , Tsanadis Konstantinos , Xydias Emmanouil , Tsoukalas Nikolaos , Charalampakis Nikolaos , Trogkanis Nikolaos , Ioannou Maria , Malizos Konstantinos N. , Tolia Maria
Published: December 2022

Pigmented villonodular synovitis (PVNS) is a proliferative, recurrent and locally invasive disease of the synovium. The symptoms of the disorder are not typical and thus it is very often misdiagnosed. Most of the times, magnetic resonance imaging presents the nodular model of development and sets the basis for the diagnosis. The final diagnosis will be set by the pathological evaluation of the lesion’s biopsy. PVNS may be localized (nodule with a clear boundary with/without presence of single pedicle) or diffuse (extensive involvement of the adjacent nerves and vessels). Depending on the extension of the PVNS, a different management approach is performed, lesion excision vs. resection, followed by radiotherapy respectively. We report a case of diffuse PVNS in the knee joint, treated with surgical excision and adjuvant radiotherapy as well as follow-up imaging after a time period of 3 years.
Type 2 Deiodinase A/G (Thr92Ala) Polymorphism and Circulating Thyroid Hormone Level of Childbearing Age Women in Area Replete with Iodine Deficiency Disorders
Authors: Wibowo Agus , Hidayat Taufiq , Wahyuningrum Sri Nuryani
Published: December 2022

BACKGROUND: Iodothyronine deiodinase (DIO) is an enzyme that regulates thyroid hormone activity. DIO consists of three types: deiodinase 1 (D1), 2 (D2), and 3 (D3). D2 is a gene that plays an important role in regulation of the biochemistry of the thyroid hormone in several tissues. D2 also plays a role in the production of triiodothyronine and controlling thyroid hormone signals. This study measured the observation that about 15% of the normal population show that D2 gene polymorphism (Thr92Ala) potentially affects the activity of D2.

AIM: This study aimed to determine D2 polymorphisms and their association with thyroid hormone levels in women of childbearing age in replete iodine deficiency disorder areas.

METHODS: Total number of subjects was 131. Analysis of serum TSH, T3, fT3, T4, and fT4 levels was done using ELISA. Polymorphism of Thr92Ala was analyzed by PCR-RFLP method.

RESULTS: The results showed that the frequencies of the genotypes Thr92Ala were AA 16.79%, AG 41.22%, and GG 41.99%, whereas the allele frequency A 37.5% and G 62.5% (p HWE = 0.171). In this study, we found no differences of TSH and thyroid hormone level between group of each allel. Mean of TSH and thyroid hormone level was on normal range.

CONCLUSION: This D2 polymorphism is associated with fT4 levels rather than fT3 but not statistically significant. Heterozygous alleles at D2 AG have higher TSH levels compared with homozygous alleles.
Un enfant adopté : quand l’intelligence s’en mêle
Authors: Monzani Stefano
Published: December 2022

Si les enfants adoptés souffrent pour la plupart de difficultés cognitives, le surinvestissement des parents adoptifs, souvent nourri par un fantasme de réparation, permet, dans bon nombre de situations, une récupération des capacités intellectuelles. Dans ce texte, je vais étudier la situation clinique d’un enfant adopté présentant un trouble de comportement et d’hyperactivité, supposé à haut potentiel par ses parents. L’idéalisation parentale de leur enfant élu, focalisée sur ses capacités de réflexion et sa maturité semblerait, d’une part, aider à entretenir ces troubles dans une boucle rétroactive et, d’autre part, à scotomiser les traumatismes vécus par leur enfant. Dans le cas de cet enfant et de sa famille, les questions des origines et celle du savoir semblent s’être mêlées puis emmêlées sans solution.
Comprendre l’effet thérapeutique de l’EMDR à l’aune de la relation thérapeutique et des théories de l’attachement
Authors: Nicolas Florian , Delahaye Aline , Gheorghiev Charles
Published: December 2022

S’inspirant de concepts et terminologies issus des neurosciences, la thérapie EMDR ( Eye Movement Desensitization and Reprocessing ), plus de trente ans après sa découverte, ne cesse de questionner quant aux principes actifs qui en font l’efficacité. Cet article propose de revenir au dénominateur commun à toute démarche psychothérapique, indépendamment de son orientation théorique : la relation thérapeutique. Se dégageant de tout présupposé neurobiologique, et se basant sur l’observation des phénomènes cliniques et interactionnels, cette lecture proposera de remettre à l’honneur cette dimension parfois oubliée des recherches portant sur les mécanismes de l’EMDR, et de discuter de possibles liens avec les théories de l’attachement.
Penser le rêve dans la pratique psychothérapique et au-delà des théories
Authors: Nguimfack Léonard , Mbangmou Romuald Stone
Published: December 2022

Dans cet article, nous revisitons le concept de rêve par une revue de ses principales conceptions théoriques dans la littérature et sa portée en psychothérapie. Nous actons également pour une théorie globale du processus onirique incluant à la fois le soma et le psychisme et toutes les phases du sommeil. Le rêve est une fonction mentale complexe, et, serait même la plus complexe selon plusieurs auteurs. Depuis la construction de la théorie freudienne des rêves, plusieurs autres théories oniriques ont vu le jour. Sauf que, la plupart de ces théories n’expliquent qu’un aspect du phénomène onirique, en se fermant aux autres pans de ce mystérieux phénomène. Par exemple, la théorie psychanalytique va expliquer la part des désirs refoulés dans le rêve, mais elle va minimiser l’aspect somatique du rêve envisagé par les neurosciences.
Using Artificial Neural Networks to Predict Hardness and Impact Toughness of Aluminum Alloy 6061-T6
Authors: Bataineh Omar , Smadi Mohammad
Published: December 2022

Predicting the material's mechanical properties is essential for reducing testing time, cost, and effort. In this study, the effect of temperature and holding time on the hardness and impact toughness of Al 6061 was investigated using the design of experiments (DOE) methodology. Analysis of variance (ANOVA) was used to analyze the results of DOE-factorial experiments. Two factors with five replicates were studied in the experiments: temperature with four levels (393.15, 423.15, 453.15, and 483.15 oK) and holding time with four levels (60, 120, 180, and 240 min). An artificial neural network (ANN) model was constructed to predict the hardness and impact toughness of precipitation-hardened 6061 aluminium alloy. The results revealed that the temperature, holding time, and interaction between them were significant factors on the hardness and impact toughness of Al 6061. ANN models' accuracy to predict the hardness and impact toughness of precipitation-hardened 6061 aluminium alloy was 99.1% and 97.6%, respectively. In this work, the ANN model accuracy was larger than ANOVA accuracy.
Effects of Basalt Fiber on Strength of Alkali-Activated Slag-Tailing Cement Bodies
Authors: Tian Shuai , Li Kun , Liu Xin , Li Yong
Published: December 2022

The influences of different quantity of basalt fiber and lead–zinc tailings on the strength of alkali-activated slag-tailings cement bodies were studied. After adding basalt fiber, the uniaxial compressive strength of the 50 and 60 g per unit tailing cement bodies increased before decreasing throughout a 7-day curing period. During a 28-day curing period, the uniaxial compressive strength of the 50 g per unit tailings cement decreased gradually, while the uniaxial compressive strength of the 60 g per unit tailings cement increased first and then decreased. Furthermore, after adding basalt fiber, the flexural strength of the 50 g per unit tailings cement body decreased gradually during a 7-day curing period, while the 60 g per unit tailings cement increased first and then decreased. Under a 28-day curing period, the flexural strength decreased first and then increased for both cement bodies. Finally, At the confining pressures of 2, 4 and 6 Mpa, the increase amplitude of the triaxial compressive strength of the cementation body was different with the addition of basalt fiber. The increase amplitude of the triaxial confining pressure from 2 to 4 Mpa was higher than that of the triaxial compression from 4 to 6 Mpa.
Ring Opening Polymerization in Polylactic Acid Production Using Different Catalyst
Authors: Binti Ghazali Nur Athirah , Ibrahim Norliza
Published: December 2022

Polylactic acid is a biodegradable polymer with wide range of applications in food packaging and medical industries. Polylactic acid is commonly derived from lactic acid which is made from sugar and starch via bacterial fermentation. Whereas the production of polylactic acid via ring opening polymerization uses lactide as its precursor. This method undergoes reaction with the presence of catalyst. In this research, polylactic acid is produced via ring opening polymerization using different catalyst. However, very few studies conducted on how the catalyst effects the molecular structure of the PLA produced. The main objective is to study the effect of using stannous octoate (SnOct2) and anhydrous lithium chloride (LiCl) as catalyst in producing PLA. Lactide is reacted with SnOct2 and LiCl at 130°C at different ratio of lactide to catalyst (Lac/Cat) of 25/1, 50/1 and 100/1 by weight. The resulting PLA is characterized using Fourier Transform Infrared Spectroscopy (FTIR) to analyse the molecular structure and UV-Visible Spectrometer (UV-VIS) to measure the concentration of the PLA obtained. The ratio of Lac/Cat shows significant difference on the PLA with SnOct2 as the catalyst but shows no significant difference on the PLA with LiCl as the catalyst. Nevertheless, LiCl can still be used as the catalyst in producing PLA which has been proved by the presence of certain peaks on the FTIR spectrum. However, further investigation needs to be carried out to understand the ROP mechanism when using LiCl as the catalyst.
Alumina Nano Powder Impact on Electrical Discharge Machining of Titanium Alloy Wire
Authors: Abed Farook Nehad
Published: December 2022

WEDM is an unconventional method of thermal machining that produces products with irregular shapes. The results of milling titanium (TI-6242) under various machining conditions that affect the WEDM process are provided. Pulse on time (Ton), pulse off time (Toff), peak current (Ip), voltage (V), wire tension (Wt), and wire feed are all considered machining parameters (Wf). They are established using an experimental design and the Box–Behnken approach to optimize the machining factors. The optimization goal is to attain the highest Material Removal Rate (MRR) and the least amount of recast layer (RL). ANOVA determines the most important factor. Moreover, a regression analysis is used to predict MRR and RL based on defined machining parameters. Ton = 120s, Toff = 50s, Ip = 11 A, Wt = 1kg, and V = 50 volt are the optimal regulatory factors for obtaining the highest MRR, depending on the consequences. Ton = 130s, Toff = 60s, Ip = 12 A, Wt = 3 kilogram, and V= 30 volt are the best control variables for achieving the lowest RL. Ton = 120s, Toff = 50s, Ip=10 A, and Wt=1kg are thought to be the ideal control parameters for achieving minimum RL and greatest MRR. In ideal machining circumstances, the microstructure of the machined surface exhibits a recast layer on the machined surface.
Effect of Ultraviolet Aging on Rheological Properties and Microstructure of Rubber Asphalt in High Altitude Area
Authors: Guo Dong Feng , Ma Xiao Jun , Ma Xiao Yan , Fang Jian Hong
Published: December 2022

High altitude and strong ultraviolet radiation in Qinghai Tibet Plateau induces the brittleness and hardening of asphalt, which leads to temperature cracks, pits and other diseases of asphalt pavement. In this paper, the accelerated UV aging test of rubber asphalt was carried out by simulating the UV radiation intensity in Xining, Qinghai Province, and the rheological properties and microstructure changes of rubber asphalt were analyzed. The results show that the complex modulus of rubber asphalt increases exponentially with the extension of UV aging time. The phase angle of rubber asphalt decreases linearly with UV aging, and the deformation recovery performance of rubber asphalt increases; UV radiation has the most significant effect on the micro morphology of rubber asphalt. With the further extension of UV aging time, micro cracks are formed in rubber asphalt, and the low-temperature crack resistance and fatigue failure resistance of rubber asphalt are gradually reduced.
Strategies Regarding High-Temperature Strength and Toughness Applications for SUS304 Alloy
Authors: Abdullah Muhammad Raies , Fang Liang , Cai Hong Neng , He Zhang
Published: December 2022

Steel alloys with high Mn and low C, low Cr wt.%, were designed based on the composition system for traditional high toughness, creep resistance, and longevity for high-temperature applications. In terms of energy resource utilization during production and refining, CALPHAD strategical optimization is preferable for all steel alloys. Thermo-Calc software calculates the phase diagrams α-BCC (Ferrite), and M23C6 (carbide) phases. The vital temperatures which are highlighted in this work are Ac3 (threshold temperature at which ferrite is fully transformed into austenite (α→γ)), and A4 (the threshold temperature at which austenite is fully transformed into Delta ferrite (γ→δ)) are essential for phase transformations. JMatPro software is used to predict the mechanical properties of steel alloys. The interfacial energies with regards to alloying elements for M23C6 are calculated to be between ~0.272 J/m-2 to ~0.328 J/m-2 for α-BCC) matrix, while γ-FCC has interfacial energy ranges to be between ~0.132 J/m-2 to ~0.168 J/m-2. This paper focuses on investigating the effect of alloying elements on phase transformations, interfacial energy, coarsening rate of carbides, and many other mechanical properties such as toughness at high-temperature applications using CALPHAD strategies.
Influence of Rejuvenator on the Properties of Bitumen and Asphalt Concrete
Authors: Pyrig Yan , Galkin Andrii , Oksak Serhii , Ilin Iaroslav , Shyika Yana
Published: December 2022

The article considers the influence of the domestic rejuvenator Lux «ЕD-L» on the properties of bitumen and asphalt concrete. The influence of the rejuvenator on the origin bitumen properties, on the properties of bitumen after RTFOT hardening, and on the rate of bitumen hardening is performed. It is shown that the properties of bitumen hardened by RTFOT method are completely restored to the level of bitumen before technological hardening under the influence of the rejuvenator. The high rate of the adsorption of additive by bitumen was proved with the evaluation of the bitumen adhesion to the mineral surface. An advantage of the rejuvenator Lux «ЕD-L» is a significant improvement in the adhesion properties of bitumen. Treatment of asphalt concrete mixtures conditioned according to the AASHTO R 30-02 method with the rejuvenator leads to the improvement of the quality indicators of asphalt concrete made on these mixtures.
Microstructure and Formation Mechanisms of Nanowires and Nanoplates ZrO2 during the ZrB2 Deposition Process
Authors: Geng Li , Zhu Yan , Cheng Su , Li He Jun
Published: December 2022

Preparation of boride by chemical vapor deposition (CVD) is sensitive to oxygen, subtle changes in oxygen concentration during the deposition of ZrB2 can induce the formation of Zirconium dioxide (ZrO2) with a novel nanoplate-stacked structure and nanowire structure. The ZrO2 nanostructure changed with - oxygen concentration. Nanowires with uniform size of 50-100 nm in diameter and over 100 μm in length were obtained at high oxygen concentration, while highly-ordered nanoplate arrays were obtained at low oxygen concentration. Both of these nanostructures were grown in situ on the surface of ZrB2-coating. In this paper, the preparation method of novelty ZrO2 nano-structures grown in situ was provided, the morphologies and compositions of the nano-structural ZrO2 were characterized and the formation mechanism was proposed, which also provides experimental basis for the industrial morphology control of ZrB2 deposited by CVD method.
Mechanical and Morphological Properties of PHB/Oil-Free Coffee Dregs (OFCD) Composites
Authors: Rocha Marisa Cristina Guimarães , Alvarez Acevedo Nancy Isabel , de Oliveira Carlos Eduardo Nazareth
Published: December 2022

Poly(3-hydroxybutyrate) (PHB) and coffee dregs (CDs) are both biodegradable materials. The latter are household wastes with no commercial value that are discarded in landfills mixed with other organic wastes. PHB has properties equivalent to polypropylene (PP), but its prohibitive cost restricts its field of application. The incorporation of this residue in a PHB matrix is a way to obtain materials with a high cost/benefit ratio. The aim of this work was to investigate the effect of adding oil-free coffee dregs (OFCDs) on the mechanical and morphological properties of PHB. Soxhlet extraction using ethanol as a solvent was used to obtain OFCDs. The PHB/OFCD composites were prepared in a twin-screw extruder. Standardized methods were used to evaluate the tensile and flexural properties. The test specimens were obtained by compression molding. Scanning electron microscopy (SEM) was applied to evaluate the morphology of the composites obtained. The data obtained showed that the incorporation of 15 wt.% of OFCD caused no significant differences in the tensile modulus, tensile strength and flexural modulus. The flexural strength decreased with the incorporation of OFCD in the PHB. However, the material obtained was interesting, since it was more attractive in terms of cost and environmental impact. SEM micrographs showed good dispersion of OFCD in PHB when the OFCD content was 5 wt.%. However, when higher levels of residues were incorporated in the PHB, the formation of agglomerates became evident. Poor interfacial adhesion between the filler and matrix was indicated by the cracks and voids revealed in the micrographs. The results obtained indicated that PHB/OFCD composites prepared with 15 wt.% of OFCD particles have potential to be used in the production of PHB materials that require high stiffness, adequate strength, and lower cost, such as sheets and thermoformed products for food, medical, personal care and laboratory applications
Adsorption of Cadmium(II) Ions from Aqueous Solutions Using Calcium Molybdate
Authors: Pereira Sandra de Cássia , Barbosa Amanda das Graças , de Figueiredo Alberthmeiry Teixeira , Barrado Cristiano Morita , Alves Vanessa Nunes , Longo Elson
Published: December 2022

The presence of toxic metals in aquatic environments poses serious problems for ecosystems and especially for human health. Numerous types of metal oxides have been used to remove these metals and other toxic organic compounds, using adsorption systems. In this work, CaMoO4 was synthesized via coprecipitation and processed for different periods of time using a microwave-assisted hydrothermal system. It was possible to synthesize CaMoO4 on room temperature without any heat treatment. In addition, small processing times in HTMW were able to produce CM with different morphologies. The effect of the reaction time on the morphology of the product and particle size was examined in SEM images. A plausible CaMO4 formation mechanism was proposed based on time and temperature parameters. The potential application of CaMO4 as an adsorbent in water treatment was also investigated and this material exhibited a favorable adsorption performance in the fast removal of cadmium(ii) ions from aqueous solution of 1 mg L-1 concentration. So, CM showing a promising potential for use in environmental remediation.
Experimental Investigations of Hydrodynamic Deep Drawing of Galvanized Steel to Form a Hemispherical and Complex Cup
Authors: Ahmed Ali Raad , Khleif Ali Abbar
Published: December 2022

In this work, a blank of galvanized steel blank with 80 mm diameter and 0.7 mm thickness and the hydromechanical deep drawing process to make a hemispherical and complex cup. Hydraulic oil was used to apply different amounts of fluid pressure. The work of this study was done in the following three states: In the first state, the experimental work was done without fluid pressure, so the product has wrinkles. In the second state, flaws like wrinkles were fixed by adding 1N/mm2. At a pressure of 1.7 N/mm2, the third state was done. The results show that a product with a blank holder force (BHF) that is neither too high nor too low may be free of defects. When BHF is low, faults in the cylinder cup look like wrinkles, and when BHF is too high, the cylinder cup breaks. So, the BHF value should change depending on the material, thickness, and nature of the product.
Intrapreneurship as a means of achieving the efficacy of state-owned enterprises
Authors: Chamba Lucy T. , Chazireni Bobo
Published: December 2022

Background: It is an imperative in most developing countries to improve the performance of state-owned enterprises (SOEs) and increase the accessibility of government services. State-Owned Enterprises have failed to deliver public value rendering most public services inefficient and costly.Aim: This study seeks to establish the influence of intrapreneurship on the efficacy of SOEs in developing countries, using the case of SOEs in Zimbabwe.Setting: The study took place in Zimbabwe.Methods: A mixed research approach was adopted and a cross-sectional survey was used to collect data from managers and employees of 39 parastatals in Zimbabwe. Data collection instruments were questionnaires and interviews. Data collected from questionnaires were analysed using STATA version 12, whilst data from interviews were analysed using thematic analysis.Results: The study revealed that most SOEs have a poor Intrapreneurship Orientation, which negatively impacts on the performance of SOEs. Most SOEs generally have low innovation levels and have not developed services in line with customer demands. However, SOEs anchored in an intrapreneurial architecture were able to achieve greater public value through innovations which led to better service delivery and cost effectiveness.Conclusion: This study advances the notion of intrapreneurship and revealed that intrapreneurship is a strategic workplace activity which can be adopted to improve SOEs’ organisational performance.Contribution: This study provides empirical evidence of the use of intrapreneurship as a systematic mechanism that can improve organisational performance and assist SOEs in emerging economies to sustain their role as engines of economic growth.
Mastering Your Fellowship: Part 1, 2023
Authors: Von Pressentin Klaus B. , Naidoo Mergan , Torlutter Michéle , Motsohi Ts'epo , Ras Tasleem
Published: December 2022

The series ‘Mastering your Fellowship’ provides examples of the question formats encountered in the written and clinical examinations, Part A of the Fellowship of the College of Family Physicians of South Africa (FCFP [SA]) examination. The series is aimed at helping family medicine registrars (and their supervisors) in preparing for this examination.
2022: An editorial reflection
Authors: Stanz Karel J.
Published: December 2022

No abstract available.
Optimization of Exercise Preconditioning Duration in Protecting from Exhausted Exercise-Induced Cardiac Injury in Rats
Authors: Ping Zheng , Li Jinyu , Sun Yawei , Zhang Xiaoli , Wang Ziwen , Cao Xuebin
Published: December 2022

The effect of different duration of exercise preconditioning (EP) on protecting from exhaustive exercise-induced cardiac injury (EECI) has been optimized in rats. Male Sprague-Dawley rats were divided into six groups: the control group, exhaustive exercise (EE) group, EP 20-min + EE group, EP 40-min + EE group, EP 60-min + EE group and EP 80-min + EE group. The EP groups were subjected to treadmill running at the intensity of 74.0%

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. Changes of exercise capacity, cardiac pathology, myocardial enzymology, electrocardiogram (ECG), cardiac function, and mitochondrial respiratory function were compared. Compared to the C group, the EE group has shown significant decrease of exercise capacity, elevation of serum N-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin-I (cTn-I) levels, cardiac morphology change, ECG disturbance, cardiac dysfunction and reduction of myocardial mitochondrial respiration function. Compared to the EE group, the EP groups have shown significant elevation of exercise capacity, decrease of serum NT-proBNP and cTn-I, improvement of cardiac function and myocardial mitochondrial electron transfer pathway complex I, II and IV activity. The correlation analyses showed protection of EP was proportional to EP duration from 20-min to 60-min. EE caused cardiac injury. EP could protect from EECI by alleviating myocardial damage, improving cardiac function and mitochondrial ETP complex I, II and IV activity. EP protection was positively correlated to EP duration from 20-min to 60-min with EP intensity fixed at 74.0%

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.
Sensitivity of Ca2+-Sensing Receptor-Transient Receptor Potential-Mediated Ca2+ Influx to Extracellular Acidity in bEND.3 Endothelial Cells
Authors: Leong Iat-Lon , Yu Chung-Ming , Shiao Lian-Ru , Chan Paul , Wu King-Chuen , Leung Yuk-Man
Published: December 2022

Ca2+-sensing receptors (CaSRs) are G protein-coupled receptors activated by elevated concentrations of extracellular Ca2+. In our previous works, we showed protein and functional expression of CaSR in mouse cerebral endothelial cell (EC) (bEND.3); the CaSR response (high Ca2+-elicited cytosolic [Ca2+] elevation) was unaffected by suppression of phospholipase C but in part involved Ca2+ influx through transient receptor potential V1 (TRPV1) channels. In this work, we investigated if extracellular acidity affected CaSR-mediated Ca2+ influx triggered by high (3 mM) Ca2+ (CaSR agonist), 3 mM spermine (CaSR agonist), and 10 mM cinacalcet (positive allosteric modulator of CaSR). Extracellular acidosis (pH 6.8 and pH 6.0) strongly suppressed cytosolic [Ca2+] elevation triggered by high Ca2+, spermine, and cinacalcet; acidosis also inhibited Mn2+ influx stimulated by high Ca2+ and cinacalcet. Purinoceptor-triggered Ca2+ response, however, was not suppressed by acidosis. Extracellular acidity also did not affect membrane potential, suggesting suppressed CaSR-mediated Ca2+ influx in acidity did not result from the reduced electrical driving force for Ca2+. Our results suggest Ca2+ influx through a putative CaSR-TRP complex in bEND.3 EC was sensitive to extracellular pH.
The Role of Exercise Intensity on Fatty Liver in Rats
Authors: Gu Xueyan , Ma Xiaocui , Mo Limin , Wang Qiyu
Published: December 2022

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is often caused by obesity. Currently, moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) are two effective treatments for reducing fat mass in patients with obesity and NAFLD. However, the comparative fat-reducing effects and underlying molecular mechanisms of MICT and HIIT remain unclear. This comprehensive study was performed on male Wistar rats treated with standard diet, high-fat diet, MICT, and HIIT to explore their comparative fat-reducing effects and corresponding molecular mechanisms. HIIT had a greater effect on hepatic vacuolation density and lipid content reduction than MICT, and triglyceride and total cholesterol levels in the serum and the liver demonstrated different sensitivities to different exercise training programs. At the molecular level, both MICT and HIIT altered the processes of fatty acid synthesis, fatty acid transport, fatty acid β-oxidation, and cholesterol synthesis, wherein the transcriptional and translational levels of signaling molecules peroxisome proliferator-activated receptors (PPARs) regulating fatty acid and cholesterol synthesis were strongly changed. Moreover, the metabolic pathways of amino acids, bile acids, and carbohydrates were also affected according to transcriptome analysis, and the changes in the above-mentioned processes in the HIIT group were greater than those in the MICT group. In combination with the search tool for the retrieval of interacting genes/proteins (STRING) analysis and the role of PPARs in lipid metabolism, as well as the expression pattern of PPARs in the MICT and HIIT groups, the MICT-and HIIT-induced fat loss was mediated by the PPAR pathway, causing feedback responses in fatty acid, steroid, amino acid, bile acid, and carbohydrate metabolism, and HIIT had a better fat-reducing effect, which may be initiated by PPAR-α. This study provides a theoretical basis for targeted therapy of patients with obesity and NAFLD.
Evaluation and Comparison on the Results of Totally Extraperitoneal Laparoscopic Surgery under General and Spinal Anesthesia for Inguinal Hernia
Authors: Sayadishahraki Masoud , Safaee Masumeh , Alinezhad Zarir
Published: December 2022

Background:

Totally extraperitoneal (TEP) hernia repair surgery is one of the recently considered hernioplasty methods. Here, in the current study, we aimed to compare the results of TEP hernia repair surgery in the two groups of general anesthesia and spinal anesthesia.

Materials and Methods:

This is a randomized clinical trial that was performed in 2018–2019 in Isfahan on 106 patients undergoing TEP inguinal hernia repair. Patients were randomly divided into two groups. The first group underwent TEP inguinal hernia repair surgery under general anesthesia and the second group of patients underwent TEP inguinal hernia repair surgery under spinal anesthesia. Data regarding surgery duration, intensive care unit admission, pain of patients, mean of analgesic injections after the surgery, and complications such as urine retention, seroma, and hematoma, and wound infection were collected. Data were compared between two groups.

Results:

We found significantly higher duration of surgery in the spinal anesthesia group (P = 0.02). Patients in the spinal anesthesia group had shorter duration of nutrition regime beginning (P = 0.002) and lower frequencies of urine retention (P = 0.001). Further analysis showed that the mean pain severity was significantly lower in spinal anesthesia group compared to general anesthesia during postoperation measurements (P = 0.001) and patients in spinal anesthesia group received less postoperation analgesics compared to the other group (P = 0.001).

Conclusion:

TEP surgery under spinal anesthesia was associated with better clinical results such as lower postoperative pain and analgesics injections compared to general anesthesia.
Association of Subclinical Hypothyroidism with Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus
Authors: Sheikhi Vahid , Heidari Zahra
Published: December 2022

Background:

Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are recognized as two common health problems. Metabolic diseases, such as dyslipidemia, obesity, and hypertension are known risk factors for NAFLD. In addition to these risk factors, other risk factors have been recently suggested, such as thyroid dysfunction.

Materials and Methods:

In this study, adult patients with T2DM were recruited. Various clinical and biochemical parameters including thyroid function tests, liver function tests, and liver sonography in all participants were assessed and compared between with and without NAFLD groups.

Results:

Data from 926 diabetic patients were analyzed; of which, 744 (80.3%) had fatty liver. The prevalence of subclinical hypothyroidism (SCH) in patients with NAFLD was 11.6% and in patients without NAFLD was 6.0% (P = 0.029). Furthermore, the prevalence of overt hypothyroidism was higher in diabetic patients with NAFLD (3.9% vs. 1.6%); this difference was not statistically significant. In univariate logistic regression analysis, hemoglobin A1c (odds ratio [OR]: 8.13); history of insulin consumption (OR: 5.35); duration of diabetes (OR: 2.20); family history of diabetes (OR: 2.85); history of antihypertensive drug use (OR: 2.14) as well as SCH (OR: 2.03) were significant variables for NAFLD. According to the multivariate logistic model, after eliminating the confounding effect of age, sex, and body mass index; the chance of developing NAFLD in patients with SCH was 2.32 times higher than patients without SCH (P = 0.014).

Conclusion:

NAFLD is extremely common in patients with T2DM. The relationship between hypothyroidism and NAFLD is independent of other risk factors.
The Effect of Increasing the Dose of Acetamiprid and Dichlorvos Pesticides on the Reproductive Performance of Laboratory Mice
Authors: Mishani Hamid Salehi , Jalalizand Alireza , Modaresi Mehrdad
Published: December 2022

Background:

Pesticides are widely used around the world. However, these chemicals are being used more frequently and at increased doses in underdeveloped and developing countries. Although the hazard of pesticides has been studied in ecological fields, the effect of residual amounts of these compounds on the physiological processes of the body has always been debated.

Materials and Methods:

In this experimental study, 45 greenhouse cucumber plants were sprayed with dichlorvos and acetamiprid pesticides in concentrations of twofold (acetamiprid 500 g/1000 L and dichlorvos 4 L/1000 L) and threefold of the recommended dose. After 24 h, the residual amount was obtained. To evaluate the residual effect of the mentioned pesticides, an equivalent of this residue was added to the drinking water of 105 mice.

Results:

Pesticide residues were obtained for twofold and threefold concentrations of the recommended dose, 1.5 and 2.5 (mg/kg cucumber) for acetamiprid and 0.5 and 1 (mg/kg cucumber) for dichlorvos, respectively. Application of these chemicals at higher doses not only significantly reduced the body weight, food consumption, testosterone production, testicular germ cells and embryo numbers, but also increased the levels of follicle-stimulating hormone and luteinizing hormone in mice.

Conclusions:

The emergence of biological disorders and reducing reproductive potential in male mice can be attributed to the addition of pesticides to their drinking water. Therefore, to reduce the hazards caused by insecticides, it is recommended to familiarize farmers with the harmful effects of overdose of pesticides and monitoring the residuals in agricultural products.