bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: A Ring Closing Metathesis‐Based Approach to (.+‐.)‐Herbertene, (.+‐.)‐α‐Herbertenol, (.+‐.)‐β‐Herbertenol and (.+‐.)‐Herbertenediol.
Authors: Srikrishna A. , Rao M. Srinivasa
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of New Steroids Possessing an Aromatic A‐Ring with a 2‐Hydroxy or a 2‐Fluoro Substituent.
Authors: Maurin Philippe , Ibrahim‐Ouali Malika , Santelli Maurice
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Benzyl 4,6‐Dimethoxy‐1,3,5‐triazinyl Carbonate as N‐Protecting Reagent.
Authors: Hioki Kazuhito , Fujiwara Miho , Tani Shohei , Kunishima Munetaka
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Routes to α‐Amino Acid β,γ‐Thioenol Ether Derivatives.
Authors: Meffre Patrick , Durand Philippe
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective C‐Allylation of 1‐C‐Alkyl‐2,3,4,6‐tetra‐O‐benzyl‐D‐glucopyranoses with Allyltrimethylsilane.
Authors: Yamanoi Takashi , Oda Yoshiki
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a C‐9 to C‐18 Building Block of the Phenalamides.
Authors: Hoffmann Reinhard W. , Haeberlin Eckart , Rohde Thorsten
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hexulose Derivatives and Lipase‐Mediated Diastereomeric Resolution in the Enantiospecific Total Synthesis of (‐)‐Talaromycins C and E.
Authors: Izquierdo Isidoro , Plaza Maria T. , Rodriguez Miguel , Tamayo Juan A.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A General QSPR Treatment for Dielectric Constants of Organic Compounds.
Authors: Sild Sulev , Karelson Mati
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pillared Interlayered Clays — An Overview.
Authors: Mitra N. K. , Maitra S.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Anodic Oxidation of Phenols Towards the Synthesis of Bioactive Natural Products
Authors: Yamamura Shosuke , Nishiyama Shigeru
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Modules for Acetylenic Scaffolding
Authors: Nielsen Mogens Broendsted , Diederich Francois
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 4‐Acetoxy‐ and 4‐Cyano‐1,3‐dioxanes in Synthesis
Authors: Sinz Christopher J. , Rychnovsky Scott D.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Heterogeneous Enzyme Mimics Based on Zeolites and Layered Hydroxides
Authors: De Vos Dirk E. , Sels Bert F. , Jacobs Pierre A.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Effects of the Carboxyl Concentration on the Solid‐State Polymerization of Poly(ethylene Terephthalate)
Authors: Duh Ben
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Self‐Assembly of Polypeptides into Amyloid Fibrils with Structural Transitions.
Authors: Mihara Hisakazu , Takahashi Yuta
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Role of Cofactors in Protein Folding
Authors: Wittung‐Stafshede Pernilla
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Crystal Structure of Catechol Oxidase: New Insight into the Function of Type‐3 Copper Proteins
Authors: Gerdemann Carsten , Eicken Christoph , Krebs Bernt
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Acid‐Catalyzed Cyclization of 2,3‐Dibenzylidenesuccinates: Synthesis of Lignans (.+‐.)‐Cagayanin and (.+‐.)‐Galbulin.
Authors: Datta Probal K. , Yau Chi , Hooper Timothy S. , Yvon Brigitte L. , Charlton James L.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metal‐Induced Regulation of Fullerene Complexation with Double‐calix[5]arene.
Authors: Haino Takeharu , Yamanaka Yuko , Araki Hiromi , Fukazawa Yoshimasa
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Terminal‐Selective Epoxidation of Linolenic Acid with an Amphiphilic Iron Porphyrin Catalyst Casted in Bilayer Membranes.
Authors: Naruta Yoshinori , Goto Masa‐oki , Tawara Toshifumi , Tani Fumito
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Synthesis of 4,5‐Disubstituted‐thiophene‐2‐amidines as Potent Urokinase Inhibitors.
Authors: Rudolph M. Jonathan , et al. et al.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Secondary and Tertiary Aminothiophenes via Palladium‐Catalyzed Amination.
Authors: Ogawa Katsu , Radke Karla R. , Rothstein Scott D. , Rasmussen Seth C.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2,5‐Disubstituted Pyrroles and Pyrrolidines by Intramolecular Cyclization of 6‐Amino‐3‐keto Sulfones.
Authors: Benetti Simonetta , De Risi Carmela , Marchetti Paolo , Pollini Gian P. , Zanirato Vinicio
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthetic Utility of Amide and Amidine Derivatives Containing Polycarbonyl Moieties in the Synthesis of β‐Aminoenones.
Authors: Ostrowska Katarzyna
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild Copper‐Mediated Intramolecular Amination of Aryl Halides.
Authors: Yamada Ken , Kubo Tetsuji , Tokuyama Hidetoshi , Fukuyama Tohru
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Highly Enantioselective Intramolecular Heck Reaction with a Monodentate Ligand.
Authors: Imbos Rosalinde , Minnaard Adriaan J. , Feringa Ben L.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N‐ and O‐Alkylation of Isoquinolin‐1‐ones in the Mitsunobu Reaction: Development of Potential Drug Delivery Systems.
Authors: Ferrer Sandra , Naughton Declan P. , Parveen Ifat , Threadgill Michael D.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Di‐ and Trisubstituted Pyrazolo[1,5‐a]pyridine Derivatives: Synthesis, Dopamine Receptor Binding and Ligand Efficacy.
Authors: Loeber Stefan , Aboul‐Fadl Tarek , Huebner Harald , Gmeiner Peter
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Antiinflammatory, Analgesic and Antiamoebic Activity Evaluation of Some Pyrimidobenzimidazole and Pyrimidopyridoimidazole Derivatives.
Authors: Sondhi Sham M. , Johar Monika , Shukla Rakesh , Raghubir Ram , Bharti Neelam , Azam Amir
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Psychotropic Activity of Unsubstituted Phosphorylacetohydrazide Derivatives.
Authors: Semina I. I. , Shilovskaya E. V. , Tikhonova N. A. , Baichurina A. Z. , Tarasova R. I. , Garaev R. S.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Transformations of Abietic Acid. Part 5. Structure Modification and Ozonization.
Authors: Presser Armin , Poetschger Irmgard , Haslinger Ernst , Huefner Antje
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Optically Active α‐Aminoalkyl α′‐Halomethyl Ketone: A Cross‐Claisen Condensation Approach.
Authors: Honda Yutaka , Katayama Satoshi , Kojima Mitsuhiko , Suzuki Takayuki , Izawa Kunisuke
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cephalostatin Support Studies. Part 20. Redox Refunctionalization of Steroid Spiroketals. Structure Correction of Ritterazine M.
Authors: Lee Seongmin , LaCour Thomas G. , Lantrip Douglas , Fuchs Philip L.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Formal Total Synthesis of (.+‐.)‐Vindoline (I) by Tandem Radical Cyclization.
Authors: Zhou Sheng‐ze , Bommezijn Sacha , Murphy John A.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electronic Structure of Some Adenosine Receptor Antagonists. VQSAR Investigation.
Authors: El‐Taher Sabry , El‐sawy K. M. , Hilal Rifaat
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Combining Recursive Partitioning and Simulated Annealing to Detect Groups of Biologically Active Compounds.
Authors: Blower Paul , Fligner Michael , Verducci Joseph , Bjoraker Jeffrey
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Status of Advanced Carbide Fuels: Past, Present, and Future.
Authors: Anghaie Samim , Knight Travis
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Advances in Synthetic Applications of Azadienes
Authors: Jayakumar S. , Ishar M. P. S. , Mahajan Mohinder P.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fullerenes.
Authors: Birkett P. R.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of Novel Lewis Acid Catalysts for Selective Organic Reactions in Aqueous Media
Authors: Kobayashi Shu , Manabe Kei
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organometallic Chemistry. Part 2. Transition Metals in Organic Synthesis: Stoichiometric Applications
Authors: Lloyd‐Jones Guy C. , Fairlamb Ian J. S.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Methods. Part 4. Heteroatom Methods
Authors: Fletcher Matthew D.
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Reagents, Reactions, and Peptidomimetics for Drug Design.
Authors: Goodman Murray , Zapf Christoph , Rew Yosup
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Classical Methods Applied to Chemical Exchange Reactions at Equilibrium
Authors: Bakac Andreja
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Pressure Mechanistic Delineation Based on Activation Volumes.
Authors: Jenner Gerard
Published: May 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Burden of illness in adult survivors of childhood cancers
Authors: Dowling Emily , Yabroff K. Robin , Mariotto Angela , McNeel Timothy , Zeruto Christopher , Buckman Dennis
Published: May 2010

BACKGROUND:

The number of adult survivors of childhood cancer in the United States is increasing because of effective treatments and improved survival. The purpose of this study was to use a national, population‐based sample to estimate the burden of illness in adult survivors of childhood cancer.

METHODS:

A total of 410 adult survivors of childhood cancer and 294,641 individuals without cancer were identified from multiple years of the National Health Interview Survey. Multiple measures of burden, general health, and lost productivity were compared using multivariate regression analyses including: logistic, polytomous logit, proportional odds, and linear models.

RESULTS:

Controlling for the effects of age, sex, race/ethnicity, and survey year, adult survivors of childhood cancer reported poorer outcomes across the majority of general health measures and productivity measures than individuals without cancer. Survivors were more likely to report their health status as fair or poor (24.3% vs 10.9%; P < .001); having any health limitation in any way (12.9% vs 3.4%; P < .001); being unable to work because of health problems (20.9% vs 6.3%; P < .001); and being limited in the amount/kind of work because of health problems (30.9% vs 10.6%; P < .001). When categorized by time since diagnosis, cancer survivors had poor health outcomes in every time interval, with the greatest limitations in the initial 4 years after diagnosis and 30 or more years after diagnosis.

CONCLUSIONS:

Across multiple measures, adult survivors of childhood cancers have poorer health outcomes and more health limitations than similar individuals without cancer. Cancer 2010. Published 2010 by the American Cancer Society.
Microparticle formation after exposure of blood to activated endothelium under flow
Authors: Macey Marion G. , Wolf Sabine I. , Lawson Charlotte
Published: May 2010

Increased numbers of circulating microparticles (MPs) are indicative of poor clinical outcome in a number of inflammatory disorders, including atherosclerosis. Platelets and megakaryocytes are a major source of MP and are identified by presence of CD42b on the MP surface. MP shed from activated platelets can be identified by presence of P‐selectin (CD62P). Tissue factor (TF) is the principal initiator of blood coagulation and its activity has been identified in MPs derived from patient plasma, which may contribute to thrombosis. Here, we have investigated by flow cytometry the expression of TF and CD62P on MP after exposure of diluted whole blood to TNF‐activated endothelial cells (EC) both under static conditions and in our newly established model of flow. MPs were significantly increased in blood subjected to flow and this was further enhanced after exposure of blood to TNF‐activated EC. MP surface expression of CD62P or TF was upregulated following exposure to TNF‐activated EC under flow compared with flow with nonactivated EC or after static coculture with and without prior EC activation. These data strongly suggest that interactions of blood with inflamed EC can modulate production of CD62P and TF bearing MP under flow conditions, and thus may contribute to a prothrombotic environment. © 2010 International Society for Advancement of Cytometry
Documentation of immunocytochemistry controls in the cytopathologic literature: A meta‐analysis of 100 journal articles
Authors: Colasacco Carol , Mount Sharon , Leiman, Gladwyn
Published: May 2010

Although a detailed description of the procedure and tissue used as controls is considered a necessary component in surgical pathology articles in which immunohistochemistry is utilized, such documentation seems less stringent in the cytopathologic literature. A comprehensive literature search was done for articles published in English within the last 15 years on nine of the most widely used antibodies in cytopathology. Individual case reports were excluded. Of the 100 articles reviewed, 13 articles were review articles or commentaries and hence not included in the analysis. Only 11 (13%) of the remaining 87 articles described positive and negative controls run on identically prepared samples. Forty‐seven articles (54%) either did not mention controls or did not run controls as separate specimens. Sixteen articles (18%) included a vague statement about controls. Twelve (14%) commented only on the negative control, included only histology tissue controls, or included cell block controls, but the study also included other types of preparations, such as cytospins. One article (1%) did not include controls because of insufficient material. The College of American Pathologists recognizes the impracticality of maintaining separate positive control samples for every possible combination of fixation, processing, andspecimen type. However, more stringent documentation of procedure and use of controls in the cytopathologic literature will ensure that immunocytochemistry results in diagnostic cytopathology as well as in research are valid and reproducible. Diagn. Cytopathol. 2011;39:245–250. © 2010 Wiley‐Liss, Inc.
Metastatic urothelial carcinoma with signet ring features: Cytomorphologic findings in abdominal paracentesis
Authors: Cimino‐Mathews Ashley , Ali Syed Z.
Published: May 2010

Signet ring cells, characterized by large clear cytoplasmic vacuoles eccentrically displacing and indenting the nuclei, seen in cytopathology effusion specimens are most commonly due to metastatic adenocarcinoma of gastric, esophageal, and breast origin. Urothelial carcinoma can display a wide range of differentiation and is an extremely rare cause of metastatic signet ring cells. Here, we report the case of a 75‐year‐old male with high‐grade urothelial carcinoma with signet ring features, who was status‐post chemoradiation and radical cystoprostatectomy. The patient subsequently developed an abdominal mass and ascites. The paracentesis cytology revealed a hypercellular specimen with malignant cells dispersed singly as well as in small fragments displaying pleomorphism, nuclear irregularity, hyperchromasia, and binucleation. Numerous malignant cells displayed well‐formed signet ring morphology, identical to adenocarcinoma. This is the first report of metastatic high‐grade urothelial carcinoma manifesting as signet ring cells in peritoneal fluid. Diagn. Cytopathol. 2011;39:132–134. © 2010 Wiley‐Liss, Inc.
Primary malignant deciduoid peritoneal mesothelioma: A report of the cytohistological and immunohistochemical appearances
Authors: Ustun Huseyin , Astarci Hesna Muzeyyen , Sungu Nuran , Ozdemir Arif , Ekinci Cemil
Published: May 2010

Malignant deciduoid mesothelioma (MDM) is a rare variant of epithelioid mesothelioma. This type of tumor might be associated with the asbestos exposure and carries a poor prognosis in general. MDM was first described by Nascimento et al. in 1994 in a peritoneal lesion of a young woman. And its diagnosis is frequently mistaken with florid mesothelial hyperplasia and peritoneal deciduosis. There are 44 MDM cases reported in the literature up today.

A 59‐year‐old woman patient referred to our clinic was identified with an abdominal mass. Computed tomography of whole abdomen of the patient showed a mass with the widest transverse dimension of 65 × 60 mm at abdominal bifurcation in the mesenteric region. The patient was diagnosed with MDM after the cytopathological examination of the fine needle aspiration biopsy performed from the mass. Consequently, she received a total mass excision and right hemicolectomy under general anesthesia.

The cytomorphological appearance of the ascitic fluid is detailed for the first time by Gillespie et al. and is described only in two manuscripts. In the present study, we aimed to report a case of a 59‐year‐old woman since she was diagnosed with MDM and because her cytological findings were further supported by histomorphological and immunohistochemical evaluations of the operation material obtained from the patient. Diagn. Cytopathol. 2011;39:402–408. © 2010 Wiley‐Liss, Inc.
Environmental policy integration: a state of the art review
Authors: Jordan Andrew , Lenschow Andrea
Published: May 2010

The principle of environmental policy integration (EPI) attracts great scholarly interest as well as widespread political backing. Political support is particularly strong in the European Union, where it enjoys a prominent quasi‐constitutional status. However, the practical fulfilment of EPI appears to lag well behind these aspirations, although the evidence base of this widely held view remains rather fragmented. This article aims to review the ‘state of the art’ in EPI research and practice from the perspective of its conceptual meaning, processes of implementation and outcomes ‘on the ground’. It finds that the political commitment to EPI is indeed widespread, especially in industrialized states, but that deep disagreement surrounds its actual application. In terms of everyday practices, ‘policy integration’ is complex and contingent, and there are few ‘best practices’ that can be easily shared between jurisdictions. Finally, knowledge about policy outcomes is very sparse indeed, and policy‐making systems seem very ill prepared to address this lacuna. Copyright © 2010 John Wiley & Sons, Ltd and ERP Environment.
Cyano‐Bridged 2D Bimetallic 4f–3d Arrays with Monolayered Stair‐Like, Brick‐Wall‐Like, or Bilayered Topologies – Rational Syntheses and Crystal Structures
Authors: Chen Wen‐Tong , Wu A‐Qing , Guo Guo‐Cong , Wang Ming‐Sheng , Cai Li‐Zhen , Huang Jin‐Shun
Published: May 2010

Three series of fourteen cyano‐bridged 2D LnIII–FeIII or LnIII–CoIII complexes, [Ln(dmso)2(H2O)(μ‐CN)4Fe(CN)2]n [Ln = Gd (1) and Er (2)], [Ln(dmso)2(H2O)3(μ‐CN)3M(CN)3]n [La–Fe (3) and Pr–Co (4)], [Ln(dmf)2(H2O)3(μ‐CN)3M(CN)3]n·nH2O [Nd–Fe (5), Gd–Fe (6), Dy–Fe (7), Er–Fe (8), Nd–Co (9), and Gd–Co (10)], [Ln(dmso)2(H2O)3(μ‐CN)3Co(CN)3]n·nH2O [Ln = Pr (11), Nd (12), and Sm (13)], and [Er(dmf)(H2O)3(μ‐CN)4Co(CN)2]n·nH2O (14) (dmso = dimethyl sulfoxide; dmf = N,N′‐dimethylformamide) were rationally prepared by the ball‐milling method, and their structures were characterized. The crystal structures of 1 and 2 reveal a sevenfold coordination environment of the Ln3+ ions and a 2D stair‐like structure, while those of 3–13 show an eightfold coordination environment of the Ln3+ ions and a 2D monolayered brick‐wall‐like topology and that of 14 exhibits an eightfold coordination environment of the Er3+ ions and a 2D bilayered topology. The relationship between the crystal structures and the controllable synthesis was also discussed.
Actinyl Compounds with Hexavalent Elements (S, Cr, Se, Mo) – Structural Diversity, Nanoscale Chemistry, and Cellular Automata Modeling
Authors: Krivovichev Sergey V.
Published: May 2010

Actinyl oxysalts with TO4 tetrahedral oxyanions (T = S, Se, Cr, Mo) demonstrate a remarkable structural diversity, owing to the flexibility of the An–O–T linkages, which results in a multitude of topological and geometrical variations. Application of graph representation of structural units allows topological classification of structures and analysis of topological and geometrical isomers. In some organically templated structures, isomerism is controlled by the interplay of hydrophobic/hydrophilic interactions between organic and inorganic substructures. The high flexibility of actinyl oxysalt complexes (in particular, in uranyl selenates) allows strong curvature of inorganic units and formation of curved nanoscale tubules assembled from [1+4+1] complexes. In some particular systems, the self‐assembly process may be modeled using a cellular automata approach.
Non‐Centrosymmetric Ammonium Rare Earth Nitrates (NH4)2Ln(NO3)5·4H2O – Crystal Structure, Crystal Growth and Optical Properties
Authors: Bohatý Ladislav , Fröhlich Roland , Held Peter , Becker Petra
Published: May 2010

For crystals of (NH4)2Ln(NO3)5·4H2O (Ln = La, Ce, Pr, Nd), the piezoelectric and the pyroelectric effect was demonstrated unambiguously. X‐ray structure determination shows that all four compounds are isomorphic, with monoclinic, non‐centrosymmetric space group Cc, and are further isomorphic to the related rubidium compounds Rb2Ln(NO3)5·4H2O. Large single crystals of the colourless compounds (NH4)2La(NO3)5·4H2O and (NH4)2Ce(NO3)5·4H2O were grown. On the basis of determined precise refractive indices and their dispersion in the wavelength region 0.365–1.083 μm, phase‐matching conditions for collinear second harmonic generation were analyzed. In both crystals, type I phase matching can be realized for wavelengths from 0.893 μm (La) or 0.892 μm (Ce) to the near IR, where first absorption bands appear.
Chiral Chalcogen Peptides as Ligands for the Catalytic Enantioselective Aryl Transfer Reaction to Aldehydes
Authors: Schwab Ricardo S. , Soares Letiere C. , Dornelles Luciano , Rodrigues Oscar E. D. , Paixão Márcio W. , Godoi Marcelo , Braga Antonio L.
Published: May 2010

A new series of chiral chalcogen peptides were synthesized from inexpensive and commercially available starting materials. The synthesized compounds were tested as catalysts in the enantioselective arylation of aldehydes by using arylboronic acids as the aryl source. The desired diarylmethanols were obtained in excellent yields and with enantioselectivities up to 91 % ee.
Diverse Strategies for the Synthesis of the Indoline Scaffold
Authors: Liu Dianyu , Zhao Guowei , Xiang Lan
Published: May 2010

Because indoline is an important intermediate of angiotensin‐converting enzyme (ACE) inhibitor and the antihypertensive drug “pentopril”, and also because it is a ubiquitous scaffold found in the structures of several naturally bioactive alkaloids such as vinblastine, strychnine, (–)‐physostigmine, ajmaline, and (+)‐aspidospermidine, the synthesis of this “privileged structure” is meaningful in the design of new biologically active medicines. This microreview describes the recent advances in the synthesis of indoline derivatives, including Cu‐ and Pd‐catalyzed reactions, metal‐free approaches (radical reaction), as well as other types of reactions.
Addition/Cycloaddition of Acetylenedicarboxylates to Open‐Chain or Cyclic Amino Carbonyl Compounds
Authors: Guerrini Giacomo , Ponticelli Fabio
Published: May 2010

Some new, interesting, and unknown heterocyclic rings and open‐chain molecules have been obtained with ease and under mild conditions by reaction of a wide range of aminocarbonyl compounds with acetylenic esters. The reactivity is highly dependent on the substituents and their positions in the starting material, which can be either cyclic (pyrazolones) or open‐chain compounds.
Online Monitoring of Microwave‐Enhanced Reactions by UV/Vis Spectroscopy
Authors: Heller Eberhard , Klöckner Jessica , Lautenschläger Werner , Holzgrabe Ulrike
Published: May 2010

Microwave‐enhanced reactions are very fast in comparison to thermal reactions. They are often finished within a few minutes. Thus, the determination of the end point often fails, because conventional analytical methods are too slow. We developed a fast method using a UV/Vis sensor, which allows a direct online monitoring of the reaction process. The potency of the method is demonstrated by means of five representative reactions.
Genetic and expression analysis of all non‐synonymous single nucleotide polymorphisms in the human deoxyribonuclease I‐like 1 and 2 genes
Authors: Ueki Misuzu , Fujihara Junko , Takeshita Haruo , Kimura‐Kataoka Kaori , Iida Reiko , Nakajima Tamiko , Kominato Yoshihiko , Yuasa Isao , Yasuda Toshihiro
Published: May 2010

Members of the human DNase I family, DNase I‐like 1 and 2 (DNases 1L1 and 1L2), with physiological role(s) other than those of DNase I, possess three and one non‐synonymous SNPs in the genes, respectively. However, only limited population data are available, and the effect of these SNPs on the catalytic activity of the enzyme remains unknown. Genotyping of all the non‐synonymous SNPs was performed in three ethnic groups including six different populations using the PCR‐RFLP method newly developed. Asian and African groups including Japanese, Koreans, Ghanaians and Ovambos were typed as a single genotype at each SNP, but polymorphism at only SNP V122I in DNase 1L1 was found in Caucasian groups including Germans and Turks; thus a Caucasian‐specific allele was identified. The DNase 1L1 and 1L2 genes show relatively low genetic diversity with regard to these non‐synonymous SNPs. The level of activity derived from the V122I, Q170H and D227A substituted DNase 1L1 corresponding to SNPs was similar to that of the wild‐type, whereas replacement of the Asp residue at position 197 in the DNase 1L2 protein with Ala, corresponding to SNP D197A, reduced its activity greatly. Thus, SNP V122I in DNase 1L1 exhibiting polymorphism exerts no effect on the catalytic activity, and furthermore SNP D197A in DNase 1L2, affecting its catalytic activity, shows no polymorphism. These findings permit us to postulate that the non‐synonymous SNPs identified in the DNase 1L1 and 1L2 genes may exert no influence on the activity levels of DNases 1L1 and 1L2 in human populations.
Generation of methane from textile desizing liquors
Authors: Opwis Klaus , Mayer‐Gall Thomas , Schollmeyer Eckhard , Dammer Christoph , Titscher Tanja , Nickisch‐Hartfiel Anna , Grün Oliver , Spurk Christoph , Schloderer Christine , Köppe Axel , Dörfler Christian , Bachus Herbert
Published: May 2010

A new strategy for the biological transformation of sugar‐containing wastewaters from the textile desizing process to biogas was developed. Here, industrial liquors were separated from the following washing step by squeezing the impregnated fabrics after desizing. These waters exhibit a chemical oxygen demand of 40 g/L and allow a direct use in microbial biogas reactors without further treatment or accumulation. After reaching balanced conditions, the microbes continuously produce biogas. Moreover, the chemical oxygen demand can be reduced up to 75%. This new technology seems to be practicable and even attractive for small‐ and medium‐sized enterprises with an annual cotton production down to 2000 t. At this stage, a reliable eco‐balance of the overall process is still pending. Further investigations will be carried out soon.
Oligodendrocyte precursors originate in the parabasal band of the basal plate in prosomere 1 and migrate into the alar prosencephalon during chick development
Authors: Garcia‐Lopez Raquel , Martinez Salvador
Published: May 2010

Oligodendrocytes are the myelin‐forming cells in the central nervous system of vertebrates. Oligodendrocyte precursors arise from multiple restricted foci distributed along the antero‐posterior axis of the developing brain. In chick and mouse embryos, oligodendrocyte precursors of the anterior forebrain emerge from neuroepithelial cells of the subpallium and migrate tangentially to invade the entire telencephalon (Olivier et al. (2001) Development 128:1757–1769). In the diencephalon, oligodendrocyte neuroepithelial precursors seem to be mainly located in the basal plate of caudal prosomeres, but very little is known about their distribution and maturation at later stages of embryonic development. Thus, in this work, we studied the origin and migration of oligodendrocyte precursos in the diencephalon of quail‐chick chimeras. Homotopic and homochronic grafts demonstrated that, during embryonic development, diencephalic oligodendrocytes emerge from a common neuroepithelial domain in the basal plate of prosomere 1 and migrate tangentially, invading the dorsal regions of the diencephalic prosomeres and the telencephalon. © 2010 Wiley‐Liss, Inc.
Astrocytes retain their antioxidant capacity into advanced old age
Authors: Liddell Jeff R. , Robinson Stephen R. , Dringen Ralf , Bishop Glenda M.
Published: May 2010

Oxidative stress has been implicated in the progression of ageing and in many age‐related neurodegenerative conditions. Astrocytes play a major role in the antioxidant protection of the brain, yet little is known about how the antioxidant defenses of astrocytes change across the lifespan. This study assessed the antioxidant capacity and glutathione metabolism of astrocytes cultured from the brains of neonatal (<24 h old), mature (12‐month‐old), old (25‐month‐old), and senescent (31‐month‐old) C57BL/6J mice. When exposed to 100 μM hydrogen peroxide, mature, old, and senescent astrocytes cleared the peroxide ∼30% more slowly than neonatal astrocytes. This difference persisted when catalase was inhibited by 3‐aminotriazole, but was abolished when glutathione was depleted by application of buthionine sulfoximine, suggesting a deficit in the glutathione system. Correspondingly, the specific glutathione reductase activity of mature, old, and senescent astrocytes was ∼30% lower than that of neonatal cultures, whereas no age‐related change was observed in the specific activities of glutathione peroxidase, catalase, or in total antioxidant capacity. In addition, the specific rate of glutathione export was almost identical in mature, old, and senescent astrocytes, but was more than double that of neonatal astrocytes. These results indicate that the antioxidant capacity and glutathione metabolism of astrocytes are preserved from mature adulthood into senescence. It is concluded that the oxidative stress seen in ageing brains is likely due to factors extrinsic to astrocytes, rather than to an impairment of the antioxidative functions of astrocytes. © 2010 Wiley‐Liss, Inc.
Effects of childhood absence epilepsy on associations between regional cortical morphometry and aging and cognitive abilities
Authors: Tosun Duygu , Siddarth Prabha , Toga Arthur W. , Hermann Bruce , Caplan Rochelle
Published: May 2010

In this study, we used surface‐based morphometry to examine whether age‐related changes in gray matter tissue thickness and depth of sulcal regions at high spatial resolution across the cortex differed in children with childhood absence epilepsy (CAE) compared to healthy control subjects. In addition, the possibility of variable brain‐cognition relationships in the CAE compared to the control group was investigated. The main findings of this study are as follows: (1) From the developmental perspective, children with CAE did not demonstrate the normal regional age‐related changes involving a decrease in cortical thickness and increase in sulcal depth. (2) None of the seizure variables, including age of onset, seizure frequency, and AEDs had a significant effect on the association between age and cortical morphometry measures in the CAE population. (3) Even though the CAE group had mean VIQ and PIQ scores in the average range, our findings suggest that they use different brain regions to perform these cognitive functions compared to healthy controls. This first study on brain morphometry and cognition in children with childhood absence seizures has important implications for advancing our understanding of brain development and cognitive comorbidity in CAE, as well as for revisiting the clinical notion that CAE is a benign disorder. Hum Brain Mapp, 2011. © 2010 Wiley‐Liss, Inc.
Emotional memories are resilient to time: Evidence from the parietal ERP old/new effect
Authors: Weymar Mathias , Löw Andreas , Hamm Alfons O.
Published: May 2010

Emotional memories can be extremely robust and long‐lasting and can contribute to the development of anxiety disorders. Despite tremendous work on neural responses underlying the memory formation of emotional events, less is known about long‐term retention. In the present study, behavioral and electrophysiological measures were used to investigate long‐term recognition memory for emotional (unpleasant and pleasant) and neutral pictures after two retention intervals (1 week vs. 1 year) in 21 male subjects. The results show enhanced recognition performance for emotional relative to neutral pictures for both test delays. On the neural side, the retrieval of emotional pictures compared to neutral pictures was accompanied after 1 week by an enhanced old/new effect (500–800 ms), originating in the parietal cortex. After 1‐year retention delay, only unpleasant but not pleasant pictures were different from neutral pictures in the recollection‐sensitive ERP component. Analysis of the subjective awareness (confidence ratings) during recognition indicated that behavioral and electrocortical response patterns were exclusively driven by high confidence responses, an indication for recollection‐based recognition. These results suggest that high arousing emotional memories were highly consistent over time relative to neutral memories. Hum Brain Mapp, 2011. © 2010 Wiley‐Liss, Inc.
(How) Does the HR strategy support an innovation oriented business strategy? An investigation of institutional context and organizational practices in Indian firms
Authors: Cooke Fang Lee , Saini Debi S.
Published: May 2010

This paper investigates how human resources are managed in firms of different ownership forms in India and the extent to which strategic human resource management (hereafter strategic HRM) techniques have been adopted to support an innovation‐oriented business strategy. Based on a qualitative study of 54 Indian managers from different firms, this study highlights the Indian institutional context for strategic HRM. It reveals the extent to which the Western approach to and configuration of high‐commitment/performance models of HR practices may differ from those found in Indian firms. This study also has a number of practical implications for HR professionals, HR practices, and organizations in the global context. © 2010 Wiley Periodicals, Inc.