bluuebunny/crossref_metadata_2025 huggingface dataset:
New classification of cytomegalovirus retinitis
Authors:   Dmitry Rogachev National Research Center of Pediatric Hematology,Oncology and Immunology, Pershin B.S.
Published: April 2022

Purpose. To present a new classification of cytomegalovirus retinitis (CMVR). Material and method. 48 patients (86 eyes) with CMVR after transplantation of hematopoietic stem cells. Ophthalmoscopy of the posterior segment of the eye with mydriasis, the introduction of an antiviral drug into the vitreal cavity with intraocular fluid sampling from the anterior chamber were performed once a week until complete elimination of cytomegalovirus copies from aqueous humor. Results. Data were obtained that allow us to state that the probability of achieving CMVR remission by the next visit is inversely proportional to the actual results of aqueous humor polymerase chain reaction and achieving remission by the next visit is impossible if there are two or more thousand copies of cytomegalovirus in aqueous humor. Conclusion. The proposed classification suggests a decision-making algorithm: in the presence of copies of the virus in the moisture of the anterior chamber –to carry out intravitreal injections of antiviral drugs, with the growth of CMV copies in the intraocular fluid –to change the drug for intravitreal administration and stop the series of injections when a negative result of the watery polymerase chain reaction is reached. moisture. Keywords: cytomegalovirus retinitis, children, classification.
Functional features of visual analyzer in patients with chronic ischemic optic neuropathy, associated with hemodynamically significant atherosclerotic internal carotid artery stenosis, after carotid endarterectomy
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Tuzlaev V.V. , Kolenko O.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation, Egorov V.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation, Kravchenko I.Z. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Smoliakova G.P. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation
Published: April 2022

Purpose. To evaluate effect of carotid endarterectomy (CE) in long-term follow-up period on course of chronic ischemic optic neuropathy (CION) associated with hemodynamically significant atherosclerotic internal carotid artery (ICA) stenosis. Material and methods. The object of study was 30 patients (30 eyes) with CION associated with hemodynamically significant atherosclerotic ICA stenosis. All patients underwent study of visual evoked potential (VEP), optical coherence tomography, Doppler ultrasonography of ophthalmic artery (OA) before and after ICA CE. Results. By the end of observation period (12 months), in patients with CION, despite the improvement blood flow in OA, there was deterioration in VEP and decrease in the thickness of the peripapillary retinal nerve fiber layer, the cause of which can be considered imbalance of energy metabolism that negatively affects the ganglion cells axons, leading to their death. Conclusion. Our studies show that further studies are needed to study the effect of ICA CE on the course of CION. Keywords: chronic ischemic optic neuropathy, ocular ischemic syndrome, hemodynamically significant internal carotid artery stenosis, visual evoked potential, optical coherence tomography.
Ten years of experience in organ-conserving treatment of uveal melanomas using a gamma knife
Authors:   Leningrad Regional Hospital, Saint-Petersburg, Golovin A.S. , Sinyavsky O.A. ,   Leningrad Regional Hospital, Saint-Petersburg, Troyanovsky R.L ,   Leningrad Regional Hospital, Saint-Petersburg,   Military medical Academy, Saint-Petersburg
Published: April 2022

Purpose. Analysis of ten years of experience in organ-conserving treatment of uveal melanomas using a gamma knife. Material and methods. The organ-preserving treatment of 73 patients with uveal melanoma aged 28 to 78 years using a gamma knife was analyzed. The radiation dose was 35-70 Gy. The follow-up period is from 6 months to 10 years. After stereotactic radiosurgery, tumor resection was performed in 35 patients. Stereotactic radiosurgery was used as monotherapy in 38 patients. Results. In 66 cases, the eyes were conserved. In the group of patients with gamma knife as a monotherapy, enucleation was performed in 4 cases due to tumor recurrence in the period 1–2 years after irradiation, in one case, repeated irradiation was applied due to tumor recurrence after 1 year, followed by enucleation 8 months after repeated irradiation. In the group of patients with tumor resection, 32 eyes were preserved without signs of tumor recurrence, in two cases enucleation was performed due to tumor recurrence 3 years after irradiation and tumor resection, in one case enucleation was performed due to terminal painful glaucoma, 4 patients from this group died from liver metastases within 2–3 years after treatment. Conclusion. The ten-year experience of using the gamma knife confirms its effectiveness in the organpreserving treatment of uveal melanomas. Keywords: uveal melanoma, organ-conserving treatment, gamma knife.
Хирургическое лечение ретинопатии недоношенных: исторический экскурс
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Kaluga Branch, Kaluga, Trifanenkova I.G. , Yudina N.N. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Kaluga Branch, Kaluga, Sidorova Y.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Kaluga Branch, Kaluga, Plakhotniy M.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Kaluga Branch, Kaluga, Vydrina A.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Kaluga Branch, Kaluga, Erokhina E.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Kaluga Branch, Kaluga
Published: April 2022

Purpose. Тo study the change in approaches to surgical treatment of ROP in the historical aspect. Large-scale multicenter researches have begun in the world to study the mechanism of ROP development since 1951. For decades, knowledge about the pathogenesis of ROP has been expanded, confirmed in practice, and since the 80 s of the last century, the development of various methods for the treatment of active ROP, depending on the stage of the disease, has begun. It has been proven that cryo- and laser retinopexy of the avascular peripheral retina is an effective method of stabilizing the pathological process in the active stages. With the accumulation of experience, it became obvious that if after laser treatment it was not possible to achieve regression of the disease, and objective markers of its further progression are determined, then expectant tactics does not make sense. The search for a clear correspondence between a pathogenetically substantiated method of treatment and the timing of its implementation to the stage of the pathological process of ROP remains relevant nowadays. Conclusion. The history of the surgical treatment of ROP is the way of the development of knowledge about this disease. Currently, a promising direction in the management of patients with active PH is to shift the timing of treatment to earlier stages. Keywords: retinopathy of prematurity, surgical treatment, vitrectomy.
Treatment of ophthalmic hypertension in patients after vitreoretinal surgery
Authors:   State Budget Institution of Rostov region ”Rostov Regional Hospital”, Rostov-on-Don, Kabardina E.V. , Akulov S.N. ,   State Budget Institution of Rostov region ”Rostov Regional Hospital”, Rostov-on-Don, Bronnikova N.S. ,   State Budget Institution of Rostov region ”Rostov Regional Hospital”, Rostov-on-Don
Published: April 2022

Purpose. To evaluate the effectiveness of treatment of ophthalmic hypertension in patients after vitreoretinal surgery with various tamponade of the vitreal cavity. Material and methods. 344 case histories of patients aged 30 to 80 years who underwent vitreoretinal intervention for macular rupture, epiretinal membrane, hemophthalmos, retinal detachment with various tamponade of the vitreal cavity in the period from 2019 to 2021 were analyzed. To detect ophthalmohypertension, all the studied patients underwent tonometry before surgery and every month after during the entire follow-up period. The observation period was 2 years. Results. Of the 46 patients who were diagnosed with ophthalmohypertension after vitreoretinal surgery, 18 patients had intraocular pressure compensation during 2 years of follow-up, they did not require hypotensive therapy. 28 patients were prescribed hypotensive therapy (carbonic anhydrase inhibitors, α2-adrenomimetics), of which 4 patients had glaucoma before vitreoretinal intervention. 2 patients were implanted with an Express anti-glaucomatous device. Conclusion. The analysis of the effectiveness of treatment of ophthalmic hypertension in patients after vitreoretinal surgery showed that compensation of intraocular pressure occurs differently in each case, an individual approach is needed. One antihypertensive drug is not always enough, in some cases it is necessary to strengthen antihypertensive therapy, and sometimes anti-glaucoma surgical interventions. Keywords: vitreoretinal surgery, ophthalmohypertension, secondary glaucoma.
Morphofunctional parameters of the eye in regmatogenic retina department with aphakia
Authors:   FSBI «NMHC named after N.I. Pirogov» of the Ministry of Health of Russia, Moscow, Karpov G.O.
Published: April 2022

In case of combined pathology, in particular aphakia and regmatogenic retinal detachment (ROS), an important point is the leveling of changes in the iridocrustal apparatus. Biomicroscopy revealed changes in the anterior part of the eye in patients of both groups. Purpose. The purpose of the study was to study the morphofunctional parameters of the eyeball in regmatogenic retinal detachment in conditions of aphakia. Material and methods. The studies were conducted on 100 eyes of patients aged 56 to 75 years with aphakia and artifakia and pathology of the vitreal cavity (regmatogenic retinal detachment with upper ruptures without involving the macula). All patients were divided into 2 groups depending on the presence or absence of IOL. Results. Analyzing the data obtained, signs such as unevenness of the anterior chamber of the eye, atrophy of the pigment border of the iris and its vascularization occur in patients of both groups. The distinctive features of the morphology of the anterior segment of the eye in the 1 st group patients are local opacification of the periphery of the cornea. There is also a tendency to increase the indicator of the presence of anterior chamber irregularity in the 1 st group patients. A distinctive feature of the change in the structural parameters of the vitreal cavity according to optical coherence tomography (OCT) is the presence of vitreomacular traction syndrome in the 1 st group patients. Conclusion. When assessing changes in the morphofunctional parameters of the eyeball when growing in aphakia, it can be concluded that in patients of the 1 st group, a significant decrease in IOP was revealed, an increase in the percentage of the presence of descemet folds, local opacity of the cornea periphery, absence of pupillary reflex, vitreous destruction, an increase in the depth, angle of the anterior chamber of the eye, an increase in the frequency of vitreomacular traction syndrome in comparison with similar indicators of patients of the 2 nd group. Keywords: aphakia, rhegmatogenous retinal detachment, vitreomacular traction syndrome.
Analysis results of pneumoretinopexy in surgical treatment rhegmatogenous retinal detachment
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Lebedev Y.B. , Khudyakov A.Y. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation
Published: April 2022

Introduction. Pneumoretinopexy is low-traumatic and minimally invasive technique for treatment retinal detachment. Purpose. Analysis clinical efficacy of pneumoretinopexy in treatment rhegmatogenous retinal detachment. Material and methods. 9 patients (9 eyes) aged 35 to 67 years (all women) were selected. Selection criteria: rhegmatogenous retinal detachment, the presence of one or two horseshoe retinal tear in the superior meridians. Results. On 3–5th days, all 9 patients had blockage of retinal tear, in 4 eyes the height of the retinal detached significantly decreased, in 5 patients had complete reattachment of the retina. Barrier laser retinal photocoagulation of the areas of retinal tears was performed, a barrier of coagulates was formed around the blocked tears. Patients were discharged on the 7 th day. Recurrent retinal detachment occurred in 2 patients (2 eyes). At the end of the follow-up period, after complete gas resorption in the vitreous chamber, visual acuity in all patients increased above 0.1, on average – 0.3. Conclusion. Pneumoretinopexy is effective in recent cases of rhegmatogenous retinal detachment with follow-up periods of up to 1 month. Pneumoretinopexy should be used with caution in eyes with pseudophakia; on the eyes with large retinal tears in the meridian below 1–11 o'clock meridians. Keywords: pneumoretinopexy, retinal detachment, recurrent retinal detachment, surgical treatment of retinal detachment.
Two-port surgery for macular pathology
Authors:   The S. Fyodorov Foundation to promote the development of advanced medical technology, Moscow, Mironov A.V. , Sharko A.S. ,   The S. Fyodorov Foundation to promote the development of advanced medical technology, Moscow, Magaryan T.O. ,   The S. Fyodorov Foundation to promote the development of advanced medical technology, Moscow, Kutin I.M. ,   The S. Fyodorov Foundation to promote the development of advanced medical technology, Moscow
Published: April 2022

Purpose. To evaluate the possibility of two-port surgical treatment of vitreomacular interface pathologies in standard surgical practice. Material and methods. The study included 24 patients (24 eyes) with macular pathology operated by the proposed two-port technique of vitrectomy 25G. The maximum corrected visual acuity before surgery was 0.2 ± 0.12. The minimum follow-up period after surgery is 1 month. Results. In all cases, it was possible to achieve anatomical restoration of the macular zone. The maximum corrected visual acuity after 1 month after surgery increased to an average of 0.6 ± 0.23. In all clinical cases, it was possible to successfully apply the two-port surgery technique. The need to return to traditional 3-port access was not required in any case. Conclusion. The proposed method for the surgical treatment of vitreomacular interface pathology through a two-port access is effective, technically simple and safe. Keywords: vitreomacular traction syndrome, macular hole, two-port vitrectomy 25G.
PENGARUH MURABAHAH TERHADAP PROFITABILITAS BANK UMUM SYARIAH DI INDONESIA
Authors: Supriansyah Muhammad , Munir Misbahul , Yuliana Indah
Published: April 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pembiayaan murabahah terhadap profitabilitas bank umum syariah di Indonesia. Profitabilitas dalam penelitian ini diukur dengan menggunakan ROA. Populasi yang digunakan adalah bank syariah yang terdaftar di BI dari tahun 2016 sampai dengan 2020, penarikan sampel menggunakan teknik purposive sampling, dan didapatkan 11 bank syariah yang memenuhi kriteria. Penelitian ini menggunakan uji statistik regresi linier sederhana dengan hasil sebagai berikut: variabel murabahah mempunyai nilai t-hitung sebesar 2,076 dan nilai t-tabel sebesar 2,00575 (t-hitung > t-tabel) dengan nilai signifikansi sebesar 0,043 < 0,05. Dengan demikian Ha diterima, yang berarti bahwa murabahah berpengaruh positif signifikan terhadap profitabilitas Bank Umum Syariah.
Outsourcing Strategies – Future Trends?
Authors: Pullan Geoff A.
Published: April 2022

Outsourcing production of bulk active ingredient manufacture has recently been a growing trend amongst many pharmaceutical companies. To consider how the trend might develop, one needs to consider the factors that have driven outsourcing and the critical role of the custom synthesis
industry in delivering expectations.
Replica-Exchange Enveloping Distribution Sampling: Calculation of Relative Free Energies in GROMOS
Authors: Rieder Salomé R. , Ries Benjamin , Champion Candide , Barros Emilia P. , Hünenberger Philippe H. , Riniker Sereina
Published: April 2022

Molecular dynamics (MD) simulations have become an important tool to investigate biological systems. Free-energy calculations based on MD are playing an increasingly important role for computer-aided drug design and material discovery in recent years. Free-energy differences between pairs of end-states can be estimated using well-established methods such as thermodynamic integration (TI) or Bennett’s acceptance ratio (BAR). An attractive alternative is the recently developed replica-exchange enveloping distribution sampling (RE-EDS) method, which enables estimating relative free-energy differences between multiple molecules from a single simulation. Here, we provide an introduction to the principles underlying RE-EDS and give an overview of the RE-EDS pipeline. In addition, we provide a description of the two complementary tools RestraintMaker and amber2gromos. We briefly discuss the findings of three recent applications of RE-EDS to calculate relative binding or hydration free energies. In all three studies, good agreement was found between the results obtained using RE-EDS and experimental values as well as values obtained using other free-energy methods.
Machine Learning Models to Accelerate the Design of Polymeric Long-Acting Injectables
Authors: Bannigan Pauric , Bao Zeqing , Hickman Riley , Aldeghi Matteo , Häse Florian , Aspuru-Guzik Alán , Allen Christine
Published: April 2022

Long-acting injectables are considered one of the most promising therapeutic strategies for the treatment of chronic diseases as they can afford improved therapeutic efficacy, safety, and patient compliance. The use of polymer materials in such a drug formulation strategy can offer unparalleled diversity owing to the ability to synthesize materials with a wide range of properties. However, the interplay between multiple parameters, including the physicochemical properties of the drug and polymer, make it very difficult to intuitively predict the performance of these systems. This necessitates the development and characterization of a wide array of formulation candidates through extensive and time-consuming in vitro experimentation. Machine learning is enabling leap-step advances in a number of fields including drug discovery and materials science. The current study takes a critical step towards data driven drug formulation development with an emphasis on long-acting injectables. A series of machine learning algorithms were trained and refined for accurate prediction of experimental drug release profiles. Analysis of the best performing model uncovered the properties of the drug and polymer that were identified to be key determinants of drug release. This information can be used to identify promising drug-polymer combinations that result in long-acting injectables with specific drug release behaviour. Importantly, implementation of this data driven approach has the potential to reduce the time, cost and resources associated with formulation development. Datasets and relevant codes used to train the machine learning models have been made openly available to encourage implementation in future drug formulation efforts.
Wastewater-Based Epidemiology for monitoring community derived antimicrobials and resistance genes: a one-year longitudinal study
Authors: Sims Natalie , Kannan Andrew , Holton Elizabeth , Jagadeesan Kishore , Mageiros Leonardos , Standerwick Richard , Craft Tim , Barden Ruth , Feil Edward , Kasprzyk-Hordern Barbara
Published: April 2022

Increasing understanding and awareness of antimicrobial resistance (AMR) is critical in tackling this growing global crisis. Wastewater-based epidemiology (WBE) is a promising approach to monitoring a range of AMR targets in communities through analysis of wastewater. This longitudinal study provides insight into antimicrobial (AA) usage within two communities in the South West of the UK, one city (Bath) and one town (Keynsham). AAs, including metabolites, from a range of different classes were quantified over the study period. Average loads of AAs were higher in Bath than for Keynsham (difference on average was 88 ± 6%) which reflected the larger population. Several AAs experienced seasonal fluctuations, such as the macrolides erythromycin and clarithromycin that were found in higher loads in the winter, whilst other AA levels, including sulfamethoxazole and sulfapyridine, stayed consistent over the study period. Several antimicrobial resistant genes (ARGs) were also studied within the city area, in order to determine how closely the abundance of these genes correlates with the levels of relevant AAs. Several genes including ermB, sul1 and intI1 were not found at statistically significant different loads in winter 2018/19 when compared to summer 2019. Due to relatively stable AA and ARG levels across 13 months monitoring time, no clear correlation was observed between absolute loads of ARGs and total loads of associated AAs by class. Hospital effluent within the city catchment was also investigated for AAs and ARGs. Several AAs were more common in hospital wastewater than in community wastewater, including sulfamethoxazole and trimethoprim. This work can help establish baselines for AA usage in communities, providing community-wide surveillance and evidence for informing public health interventions.
Visible-light-responsive self-assembled complexes: improved photoswitching properties by metal ion coordination
Authors: DiNardi Ray , Douglas Anna O. , Tian Ruoming , Price Jason , Tajik Mohammad , Donald William A. , Beves Jonathon
Published: April 2022

A photoswitchable ligand based on azobenzene is self-assembled with palladium(II) ions to form a [Pd2(E-L)4]4+ cage. Irradiation with 470 nm light results in the near quantitative switching to a monomeric species [Pd(Z-L)2]2+. The assembled structures improve the selectivity of photoswitching towards the metastable isomer and increase its thermal lifetime.
Impact of Nanoparticle Size and Surface Chemistry on Peptoid Self-Assembly
Authors: Monahan Madison , Homer Micaela , Zhang Shuai , Zheng Renyu , Chen Chun-Long , DeYoreo James , Cossairt Brandi
Published: April 2022

Self-assembled organic nanomaterials can be generated by bottom-up assembly pathways where the structure is controlled by the organic sequence and altered using pH, temperature, and solvation. In contrast, self-assembled structures based on inorganic nanoparticles typically rely on physical packing and drying effects to achieve uniform superlattices. By combining these two chemistries to access inorganic-organic nanostructures, we aim to understand the key factors that govern the assembly pathway and structural outcomes in hybrid systems. In this work, we outline two assembly regimes between quantum dots (QDs) and reversibly binding peptoids. These regimes can be accessed by changing the solubility and size of the hybrid (peptoid-QD) monomer unit. The hybrid monomers are prepared via ligand exchange, assembled, and the resulting assemblies are studied using ex-situ transmission electron microscopy as a function of assembly time. In aqueous conditions, QDs were found to stabilize certain morphologies of peptoid intermediates and generate a final product consisting of multilayers of small peptoid sheets linked by QDs. The QDs were also seen to facilitate or inhibit assembly in organic solvents based on the relative hydrophobicity of the surface ligands, which ultimately dictated the solubility of the hybrid monomer unit. Increasing the size of the QDs led to large hybrid sheets with regions of highly ordered square packed QDs. A second, smaller QD species can also be integrated to create binary hybrid lattices. These results create a set of design principles for controlling the structure and structural evolution of hybrid peptoid-QD assemblies and contribute to the predictive synthesis of complex hybrid matter.
ENVIRONMENTAL ASPECTS OF HYDRAULICS OF ROAD CULVERS
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Chernykh O.N. , Burlachenko V.A.
Published: April 2022

The article touches upon the main environmental aspects of the hydraulics of road and environmental structures in typical landscape conditions. Environmental technologies that contribute to the stabilization of the natural ecological system are considered. Particular attention is paid to technical and reclamation measures on road sections with culverts to ensure their safe and reliable operation.
SOME FEATURES OF PRESENTING THE QUESTION OF COMPRESSIBILITY OF A LIQUID IN HYDRAULICS COURSES FOR CONSTRUCTION AND ENVIRONMENTAL PROTECTIONS
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Burlachenko V.A.
Published: April 2022

The article analyzes the features of taking into account the compressibility of a liquid in solving problems of hydraulics and the operation of hydraulic systems. Particular attention is paid to the completeness of the consideration of the physical properties of liquids in the study of the discipline "Hydraulics" in accordance with the formation of research competencies and the direction of professional training of bachelors.
ON COSSACK REGIMENT OF MILITARY SERGEANT GREKOV OF THE 20TH (YUDIN OF THE 2ND, KRASNOV OF THE 3RD) ON THE CAUCASIAN LINE IN 1804-1812
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Zakharevich A.V.
Published: April 2022

The history of the everyday military service of the ordinary Don Cossack regiment on the Caucasian line in the period from 1804 to 1812, immediately preceding the beginning of the so-called Great Caucasian War of the 19th century, is described. The author of the article proposes to consider this time as a prologue to the conflict and the initial period of the Great Caucasian War with the recalcitrant highlanders. The presented history of frontier life and participation in the hostilities of the Cossack regiment is investigated on the basis of the service records of the Cossack officers and regiment commanders. The author examined the disciplinary violations of the Cossacks and officers of the regiment, which was one of the reasons for the change of several regimental commanders. Later, the regiment managed to deservedly regain its good name, and its Cossacks and officers were able to distinguish themselves in battles and campaigns of the Russo-Persian War of 1804-1813. in Transcaucasia, receive awards, ranks and return with honor at the end of his service to the Don in 1817.
STUDY OF THE PROPERTIES OF STEEL ENAMELED SURFACE FOR SILO TOWERS
Authors:   Russian State Agrarian University - Moscow Timiryazev Agricultural Academy, PAVKIN DMITRIY YU.
Published: April 2022

One of the technologies for obtaining and storing high-quality silage and haylage is the use of silo towers. The authors propose to manufacture silo towers from high-strength and corrosion-resistant steel sheets, coated with glass enamel, which has a lower coefficient of sliding friction than steel and concrete, as well as high resistance to aggressive environments. The aim of the study was to determine the properties of the glass-enamel coating of steel parts for the manufacturing of tower-type storages. A glass-enamel coating from a frit of glass-enamel brand MK-5 was applied to prepared sheets of steel 09G2S using a spray gun. The total thickness of the enameled coating ranged from 200 to 350 nm. Steel sheets were baked at a temperature of 850°C for 30 minutes. The thickness of the enamel coating was determined with an Olympus GX51 microscope. The roughness was determined using a TAYLOR HOBSON Surtronic 25 profilometer. The adhesive properties of the coating were studied using a Positest AT-M adhesive meter. Each test piece was tested twice. The tests were carried out on a sheet of 0.06 m2. The coefficient of sliding friction was determined on an adapted test bench. Laboratory tests with silage mass were carried out according to the developed methodology. Studies of the steel surface with a glass-enamel coating showed that the average thickness of the enameled layer was 690 nm, the roughness was 0.01 μm, and the adhesion was 5.25 MPa. The sliding friction coefficient of sliced plant materials on the enameled steel surface was 0.15, which is 2.6 and 3.2 times lower than that of non-enamelled steel and concrete, respectively. The authors have made conclusions about the possibility of using steel 09G2S in silo towers as a suitable sustitute for steel 65G and the sufficient efficiency of the chosen enameling technology.
EVALUATING METHODS OF ALCOHOL SUPPLY TO DIESEL ENGINE CYLINDERS OF AN EXPERIMENTAL INSTALLATION
Authors:   Russian State Agrarian University - Moscow Timiryazev Agricultural Academy, GAIDAR SERGEY M
Published: April 2022

The main problem of modern internal combustion engines at present is the growing shortage of fuel and the increase in environmental safety requirements. To solve this problem, the authors suggest adding alcohol to diesel fuel. This additive – ethanol or methanol – will help reduce harmful emissions of combustion products into the atmosphere and increase the efficiency of the internal combustion engine in the main operating modes. The method of feeding the mixture into the combustion chamber will have a great effect on the combustion process of the fuel-air mixture with alcohol. There is a large number of ways to supply alcohol to the engine, but their comparative characteristics have not been fully studied yet. To evaluate various methods of introducing alcohol into a diesel engine, an experimental installation including an electric brake balanced machine and a diesel engine has been developed. The installation allows the diesel engine to be loaded to the required torque value and makes it possible to record the main mechanical parameters of the engine. In this study, the authors considered the supply of alcohol in the diesel engine cylinders with two methods: in the form of an emulsion with fuel and with air on the intake stroke (in the intake manifold). The unit will quantify at different engine operating modes and the proportion of alcohol delivered both as an emulsion and with air. The research will help assess the feasibility of using alcohol additives and adjust the theoretical justification of the processes occurring during the combustion of the fuel-alcohol mixture in the cylinder.
Супрамолекулярные соединения, образованные металл-органическими координационными полимерами и органическими фотохромами
Authors: Семионова В.В. , Глебов Е.М.
Published: April 2022

Рассмотрены супрамолекулярные соединения (далее — аддукты), полученные в результате прямого инкорпорирования органических фотохромов в полости металл-органических координационных полимеров (МОКП) — в англоязычной литературе их часто обозначают как материалы Photoswitch@MOF. В приведенных публикациях по фотопереключаемым МОКП эти соединения не рассмотрены достаточно подробно. Обзор начинается кратким экскурсом в историю органических фотохромных соединений, рассмотрением классов фотохромов, сохраняющих свойства в твердом состоянии, и описанием способов улучшения характеристик таких соединений с помощью супрамолекулярной химии. Затем рассмотрены все классы органических фотохромов, для которых созданы аддукты типа Photoswitch@MOF. Особое внимание уделено количественному измерению спектральных и фотокинетических параметров аддуктов и проблемам их фото­стабильности, а также исходных МОКП. Наиболее перспективными в практическом плане представляются аддукты органических фотохромов с поверхностными пленками МОКП — соединения типа Photoswitch@SURMOF.
Features of development of root systems of plants of various cenosis in dry areas of the Volga region
Authors: Buzueva Anastasia Sergeevna , Derevyagin Sergei Sergeevich , Efimova Valentina Ivanovna , Nesvetayev Mikhail Yuriyevich , Larkin Maxim Anatolievich
Published: April 2022

The aim of the study was to establish the growth rate of the root and vegetative mass of cenoses (virgin land, fallow land, arable land under spring wheat) in the slope agricultural landscape of the Saratov region at various levels of moisture and fertilizer application. The study of the root systems of cenoses was carried out according to the Taranovskaya method. Samples of spring wheat were taken at the end of the growing season, on phytocenoses - during the flowering period of 75% of plants. The botanical composition of phytocenoses has been determined. The differences in the productivity of plant mass and root mass, in years with different SCC, as well as the introduction of nitrogen fertilizer. The rates of phytocenosis biomass humification are estimated. The proportions of the dominant families on the virgin land and the fallow land were cereals 25%, legumes 45% and complex flowers 30%.On average, the maximum root mass in a meter-thick layer of soil was observed on virgin lands - 1.9 t / ha, the minimum on spring wheat - 1.1 t / ha, intermediate - on deposits - 1.2 t / ha. Under drought conditions, the largest mass of roots in a meter-thick layer of soil was found on the deposit — 0.8 t / ha, with sufficient moisture — on virgin soil — 2.6 t / ha. Under drought conditions, the bulk of the roots are concentrated in the lower soil layers, with high moisture in the upper layers. The introduction of 60 kg / ha of nitrogen in the form of ammonium nitrate increased the mass of the roots of all cenoses by 27.3%. For an average of three years, the maximum amount of humus during humification of plant residues on fertilized (0.40 t / ha) and unfertilized (0.20 t / ha) background is formed under virgin soil.
Influence of drying methods on the quality of grain fiber of alcohol production
Authors: Ovtov Vladimir Alexandrovich , Tsurenko Pavel Denisovich , Gorshkov Kirill Andreevich , Tretyakov Nikita Evgenievich
Published: April 2022

The article provides a substantiation of the kinematic parameters of the drive of the shaft of the planting apparatus of the onion planter, which ensures the supply of onion with the bottom down at a speed range from 3.6   to 6.48 km / h, and also presents the design of a continuously variable gearbox and describes its work.
Influence of sowing time on the yield of spring wheat in Northern Kazakhstan
Authors: Tulayev Yuriy Valerievich , Somova Svetlana Vladimirovna , Abuova Altynay Burkhatovna , Tulkubayeva Saniya Abiltaevna
Published: April 2022

The research was carried out in order to determine the most optimal terms of sowing spring wheat when cultivating on a stubble precursor in the conditions of southern chernozems of the Kostanay region. The terms of sowing of spring wheat of the «Omskaya 18» variety were studied: May 15 (control), May 18, May 22, May 25, May 27, May 30 and June 05 in the fields of the 4-field grain-steam (steam – wheat – wheat – wheat) crop rotation.Soil cultivation technology- No-till.Records and observations were carried out according to the standard generally accepted methodology. An agrochemical survey at the experimental site showed that before sowing, the soil supply with nitrate nitrogen was characterized as low, mobile phosphorus – average, and exchange potassium – very high. On average, for the 2018-2020 years of research, the reserves of productive moisture in the soil during the sowing of spring wheat were characterized as good. It was found that the low  on average 1.47t/ha,  yield of spring wheat at the early sowing date of May 15, 2020, was primarily due to the lack of productive precipitation and high temperatures, which fell on a critical phase of development for the crop, affecting the grain filling. For the period of 2018-2020 years yield apparently were increased. As a matter of fact results get up to +0,43 t/ha for per hectare from 25th may and  get up to 1,90-1,99 tons for per hectare in average. It was revealed that the sowing dates are reflected on the quality. So, an early date decreases the full-scale grain weight, meanwhile sowing, from 22th May till the 5th June formed the grains of the second class.
The influence of agricultural techniques on the seed productivity of early potato varieties in specific soil and climatic conditions of the Smolensk region
Authors: Chehalkova Larisa Konstantinovna , Konova Aminat Msostovna , Gavrilova Anna Yurievna
Published: April 2022

The objects of research were three varieties of potatoes of the super-elite class Snegir, Zhukovsky early and Dolphin. On the basis of the conducted studies, it was found that on average for three years, the number of main stems on potatoes was greater with a planting scheme of 70x25 cm on all the studied varieties. The most productive variety was Zhukovsky early - up to 4.0 pcs./bush. Visual assessment of plants for viral infection during the growing season showed that viral diseases were observed in both mild and severe forms. Plant diseases increased at the third term of removal of the tops and the planting pattern of 70x35 cm on all the studied potato varieties. The increase in both the total yield and the yield of tubers of the seed fraction in all the studied varieties was influenced by the planting scheme. The maximum size of the potato yield reached with a standing density of 57.1 thousand pieces/ha (70x25 cm). In the Snegir and Dolphin varieties, the yield of tubers of the seed fraction was the highest in the variant with the second term of removal of the tops and amounted to 7.1 and 15.1 t/ha, respectively, in the Zhukovsky early variety - with the third term of removal of the tops (12.9 t/ha). The conducted post-harvest tuberous analysis of potatoes did not show a clear dependence of the damage of tubers by diseases on the planting schemes and the timing of removal of the tops.
Influence of bio-preservatives in the process of silage of corn and sugar sorgo on fermentation quality
Authors: Erokhina Anna Viktorovna , Sazonova Irina Aleksandrovna , Chernykh Tamara Nikolaevna
Published: April 2022

The article discusses the results of laboratory studies to determine the effect of the introduction of bio-preservatives AiBi 15.10 F and BIO-SIL during silage of corn and sugar sorghum. The dependence of biochemical processes during silage on the type of bio-preservative was revealed, which in turn had a positive effect on the course of lactic acid fermentation. Bioconservative AiBi 15.10 F promoted a more intense accumulation of lactic acid in comparison with BIO-SIL and the control experiment. We saw a higher nutritional value for sorghum and mixed silage compared to corn silage.
Информационно-аналитическое обеспечение бизнес-процессов в условиях инновационных ориентиров
Authors:   Финансовый университет при Правительстве РФ, Земляк С.В. , Ганичева О.М. ,   Финансовый университет при Правительстве РФ, Гусарова О.М. ,   Финансовый университет при Правительстве РФ, Дедов Е.Г. ,   Смоленский государственный медицинский университет, Крамлих О.Ю. ,   Финансовый университет при Правительстве РФ, Куксин Р.П. ,   Финансовый университет при Правительстве РФ, Ложкина С.Л. ,   Московский международный университет, Лапшова О.А. ,   Финансовый университет при Правительстве РФ, Ноздрева И.Е. ,   Финансовый университет при Правительстве РФ, Прохоренков П.А. ,   Финансовый университет при Правительстве РФ, Сивакова С.Ю. ,   Финансовый университет при Правительстве РФ, Сапожникова С.М. ,   Смоленский государственный университет, Тарасова А.Ю. ,   Самарский государственный технический университет, Тищенкова Г.З. ,   Финансовый университет при Правительстве РФ, Смоленский филиал, Хроменкова Г.А. ,   Финансовый университет при Правительстве РФ, Смоленский филиал, Четвертакова Е.В. ,   Брянский государственный университет им. акад. И.Г. Петровского
Published: April 2022

Коллективная монография подготовлена по результатам научно-исследовательской работы в рамках хоздоговорного задания ФГБОУ ВО «Финансовый университет при Правительстве Российской Федерации» на 2021 год по теме: «Информационно-аналитическое обеспечение бизнес-процессов в условиях инновационных ориентиров». В монографии отражены основные направления и механизмы бизнес-процессов информационно-аналитического обеспечения в России, где ведущую роль играют инновационные ориентиры, которые должны своевременно отражать реалии социальной действительности, создавая прочную основу для реализации бизнес-процессов. Материалы монографии ориентированы на широкий круг читателей, представителей государственного и муниципального управления, руководителей бизнес-структур, научных работников, преподавателей, аспирантов, студентов, других лиц, заинтересованных в развитии инновационной экономики.
Словарь-справочник по социологии
Authors:   Российская академия народного хозяйства и государственной службы при Президенте РФ, Акмалова А.А. , Капицын В.В. ,   Московский государственный университет им. М.В. Ломоносова, Миронов А.В. ,   Московский педагогический государственный университет, Мокшин В.К. ,   Северный (Арктический) федеральный университет им. М.В. Ломоносова
Published: April 2022

В словаре даны основные понятия, используемые в процессе изучения социологии, отражен вклад отечественных и зарубежных ученых в развитие социологической науки. Для студентов высших учебных заведений.
LEARN TO READ AND DISCUSS POLITICS
Authors:   Дипломатическая академия МИД РФ, Данилина А.Е. , Коробцева Н.Р. ,   Московский государственный лингвистический университет, Толубеева Е.В. ,   Дипломатическая академия МИД РФ
Published: April 2022

Пособие предназначено для изучающих английский язык с целью работы в области международных связей. Профессионально-ориентированные тексты из англоязычной прессы, представленный в таблицах грамматический материал, комплекс упражнений и творческих заданий, а также тематический словарь, сопровождающий каждый урок, обеспечивают глубокое усвоение учебного материала, расширение словарного запаса и развитие профессиональных компетенций, таких как чтение оригинальных текстов общественно-политического характера, перевод, реферирование и обсуждение широкого круга внешнеполитических тем. Пособие уже много лет успешно используется в учебном процессе на среднем этапе обучения при подготовке бакалавров и магистров по направлению «Международные отношения» в Дипломатической академии МИД России.
Penerapan Malcolm Baldrige Terhadap Penanganan Covid-19 Puskesmas Kota Dumai Provinsi Riau
Authors: Dainingsih Eka Wahyu , Enimay Enimay , Hartono Budi
Published: April 2022

Penanganan COVID-19 dipuskesmas termasuk pelayanan Kesehatan yang kepada public sehingga diperlukan pelayanan yang bermutu dari segala aspek. Penelitian ini bertujuan untuk menganalisis penanganan COVID-19 dan menentukan level  puskesmas dengan motode Malcolm Baldrige di Puskemas Kota Dumai. Penelitian ini di lakukan pada bulan Agustus – Oktober 2021dengan menggunakan desain Cross Sectional. Populasi Penelitian ini adalah Tim COVID-19 di puskesmas. Jumlah sampel 129 dengan teknik Purposive Sampling. Penelitian ini menggunakan desain Kuantitatif analitik dimana di lakukan uji analisi univariat dan bivariat dengan nilai P = < 0,05. Variable independen adalah Kepemimpinan, Perencanaan Strategis, Fokus Pasien, Pengukuran, Analisis dan manajemen, Fokus pada tim, Fokus pada proses, dan Hasil Kinerja. Sedangkan Variabel  dependent adalah  pelaksanaan penanganan  COVID-19 di Puskesmas. Pengumpulan data di lakukan melalui kuesioner yang dibagikan kepada responden. Mayoritas kategori kurang baik yaitu kepemimpinan 51,9%, perencanaan strategis 59,7%, fokus pada pasien 58,9%, pengukuran, analisis dan manajemen 70,9%, fokus pada tim 74,4%, fokus pada proses 75,2% dan hasil kinerja 51,9%. Observasi mayoritas penanganan  Covid-19 kategori kurang baik  66,7%.  Mayoritas terdapat hubungan antara Malcolm Baldrige dengan Penanganan COVID-19 (P = < 0,050). Hanya Fokus pada Proses yang tidak berhubungan (P = > 0,943) dengan penanganan COVID-19. Puskesmas kota Dumai perlu menganalisis Penanganan COVID-19 dengan motode Malcolm baldrige, sehingga puskesmas dapat memberikan pelayanan yang bermutu bagi publik.
Efektivitas Penggunaan Media Video Tutorial dalam Peningkatan Pengetahuan Mahasiswa pada Pembelajaran Praktikum Manajemen Rekam Medis
Authors: Sugiarto Puput , Suharyo Suharyo
Published: April 2022

Pandemi Covid-19 mulai menjangkit masyarakat Indonesia sejak bulan Maret 2020 hingga kini. Selama masa pandemi Covid-19, diberlakukan pembatasan kegiatan sosial berskala besar untuk mencegah semakin bertambahnya penularan Covid-19. Salah satu yang terdampak adalah sektor pendidikan tinggi vokasional dimana pendidikan diselenggarakan dengan metode pembelajaran dalam jaringan. Diperlukan pengembangan dalam implementasi pembelajaran praktikum melalui inovasi media pembelajaran menggunakan video tutorial yang bertujuan agar kompetensi mahasiswa tetap tercapai. Tujuan penelitian ini adalah untuk mengetahui perbedaan pengetahuan mahasiswa tentang manajemen rekam medis sebelum dan sesudah diberikan  media video tutorial. Desain penelitian yang digunakan adalah pra eksperimen dengan rancangan one group pretest-postest. Sampel yang diambil dalam penelitian ini sebanyak 97 mahasiswa melalui teknik total sampling. Hasil penelitian dianalisis menggunakan uji wilcoxon dan diperoleh hasil bahwa ada perbedaan signifikan terhadap pengetahuan mahasiswa tentang manajemen rekam medis sebelum dan sesudah diberikan media video tutorial dalam pembelajaran praktikum. Dengan diterapkannya video tutorial dalam pembelajaran praktikum ini, mampu mewujudkan pembelajaran praktikum yang efektif bagi mahasiswa.
Kesetaraan dan Keadilan Gender dalam Bingkai Teologi Hospitalitas Pentakostal
Authors: Rinukti Nunuk , Siahaan Harls Evan R. , Putri Agustin Soewitomo
Published: April 2022

Abstract. This manuscript is a study considering to the phenomenon of gender discrimination that still occurs in Christianity. The purpose of this study was to construct the idea of gender equality and justice within the framework of Pentecostal Hospitality Theology. The method used in this research was descriptive analysis and constructive argumentative using literature data related to Hospitality Theology, especially, the Pentecostalism’s response to the issue of gender equality and justice. As a result, Hospitality Theology is a theological construction that expresses openness to all differences equally and fairly. In conclusion, Pentecostal Hospitality Theology cannot be separated from the event of the outpouring of the Holy Spirit. It departs from the narrative virtues of the early church which welcomed different and foreign identities in equality and justice.Abstrak. Naskah ini merupakan sebuah kajian yang memperhatikan fenomena diskriminasi gender yang masih terjadi di kekristenan. Tujuan kajian ini adalah mengonstruksi ide kesetaraan dan keadilan gender dalam bingkai Teologi Hospitalitas Pentakostal. Metode dalam penelitian ini adalah analisis deskriptif dan argumentatif konstruktif dengan menggunakan data literatur yang terkait dengan Teologi Hospitalitas, khususnya sikap Pentakostalisme terhadap isu kesetaraan dan keadilan gender. Hasilnya, Teologi Hospitalitas merupakan konstruksi teologis yang mengekspresikan keterbukaan pada segala perbedaan secara setara dan berkeadilan. Sebagai kesimpulan, Teologi Hospitalitas Pentakostal tidak dapat dilepaskan dari peristiwa pencurahan Roh Kudus dan berangkat dari virtue naratif jemaat mula-mula yang menyambut identitas berbeda dan asing dalam kesetaraan dan keadilan.