bluuebunny/crossref_metadata_2025 huggingface dataset:
The RNA m6A modification might participate in microglial activation during hypoxic–ischemic brain damage in neonatal mice
Authors: Su Xiaojuan , Huang Lingyi , Li Shiping , Ying Junjie , Zhao Fengyan , Wang Shaopu , Liu Qian , Qu Yi , Mu Dezhi
Published: August 2023

Background

The RNA m6A modification has been implicated in multiple neurological diseases as well as macrophage activation. However, whether it regulates microglial activation during hypoxic-ischemic brain damage (HIBD) in neonates remains unknown. Here, we aim to examine whether the m6A modification is involved in modulating microglial activation during HIBD. We employed an oxygen and glucose deprivation microglial model for in vitro studies and a neonatal mouse model of HIBD. The brain tissue was subjected to RNA-seq to screen for significant changes in the mRNA m6A regulator. Thereafter, we performed validation and bioinformatics analysis of the major m6A regulators.

Results

RNA-seq analysis revealed that, among 141 m6A regulators, 31 exhibited significant differential expression (FC (abs) ≥ 2) in HIBD mice. We then subjected the major m6A regulators Mettl3, Mettl14, Fto, Alkbh5, Ythdf1, and Ythdf2 to further validation, and the results showed that all were significantly downregulated in vitro and in vivo. GO analysis reveals that regulators are mainly involved in the regulation of cellular and metabolic processes. The KEGG results indicate the involvement of the signal transduction pathway.

Conclusions

Our findings demonstrate that m6A modification of mRNA plays a crucial role in the regulation of microglial activation in HIBD, with m6A-associated regulators acting as key modulators of microglial activation.
Male characteristics and contraception in four districts of the central region, Ghana
Authors: Longla Terence A. , Ogum-Alangea Deda , Addo-Lartey Adolphina , Manu Adom A. , Adanu Richard M.K.
Published: August 2023

Background

A lack of male involvement in contraception can negatively affect its practice. To promote male participation in family planning, there is a dire need to understand male attributes that play a role in contraception. This study focuses on the male characteristics that influence the practice of traditional and modern methods of contraception.

Methods

This study is a secondary analysis of quantitative data obtained from the baseline assessment of the Ghana Community-Based Action Teams Study that aimed to prevent violence against women in the Central Region of Ghana in 2016. The analysis included 1742 partnered males aged 18–60 years. Chi-square test, t-test and logistic regression analyses were used to assess the association between male characteristics and the practice of contraception (significance level = 0.05).

Results

The prevalence of contraception was 24.4% (95% CI = 20.8–28.5). Significant male characteristics that were positively associated with the practice of contraception in adjusted models were: post-primary education (AOR = 1.96, 95% CI = 1.27–3.04), perpetration of Intimate Partner Violence (AOR = 1.83, 95% CI = 1.49–2.26), and the number of main sexual partners (AOR = 1.78, 95% CI = 1.15–2.75). However, wanting the first child (AOR = 0.71, 95% CI = 0.54–0.94) and male controlling behaviour (AOR = 0.7, 95% CI = 0.49–0.99) statistically significantly associated with reduced odds of practicing contraception.

Conclusion

Male partner characteristics influence the practice of contraception. Family planning sensitization and education programs should target males who are less likely to practice contraception.
Ramp lesion in anterior cruciate ligament injury: a review of the anatomy, biomechanics, epidemiology, and diagnosis
Authors: Bae Bo Seung , Yoo Sunin , Lee Sang Hak
Published: August 2023

Ramp lesions, commonly observed in patients with anterior cruciate ligament (ACL) injuries, have been previously defined as longitudinal tears around the meniscocapsular junction. However, the definitions and interpretations of ramp lesions have varied, emphasizing the need to confirm their presence before surgery and the importance of direct visualization using arthroscopy. Recent histological studies have reported new findings on ramp lesions, shedding light on their attachment mechanisms. The anatomical structures around the ramp lesion, such as the posterior horn of medial meniscus (PHMM), semimembranosus (SM), posteromedial (PM) capsule, and meniscotibial ligament (MTL), were assessed regarding how these structures could be attached to each other. The studies of ramp lesions have also contributed to the progression of biomechanical studies explaining the cause and effects of ramp lesions. Ramp lesion has been proven to stabilize the anteroposterior (AP) instability of ACL. In addition, various laboratory studies have demonstrated the relationship between rotational instability of the knee joint and ramp lesions. The analysis of risk factors of ramp lesion helped to understand the injury mechanism of the lesion. Many authors have evaluated the prevalence of ramp lesions in patients with ACL injuries. The development of arthroscopy techniques has influenced the outcomes of ACL reconstruction with the easy detection of ramp lesions. This review article aims to analyze the past findings and recent advancements in anatomical, biomechanical, and epidemiological studies of ramp lesions in patients who underwent ACL reconstruction, and provide various perspectives ramp lesions in patients with ACL reconstruction.
Artificial Intelligence Model Assisting Thyroid Nodule Diagnosis and Management: A Multicenter Diagnostic Study
Authors: Ha Eun Ju , Lee Jeong Hoon , Lee Da Hyun , Moon Jayoung , Lee Haein , Kim You Na , Kim Minji , Na Dong Gyu , Kim Ji-hoon
Published: August 2023

Context

It is not clear how to integrate artificial intelligence (AI)-based models into diagnostic workflows.

Objective

To develop and validate a deep-learning–based AI model (AI-Thyroid) for thyroid cancer diagnosis, and to explore how this improves diagnostic performance.

Methods

The system was trained using 19 711 images of 6163 patients in a tertiary hospital (Ajou University Medical Center; AUMC). It was validated using 11 185 images of 4820 patients in 24 hospitals (test set 1) and 4490 images of 2367 patients in AUMC (test set 2). The clinical implications were determined by comparing the findings of six physicians with different levels of experience (group 1: 4 trainees, and group 2: 2 faculty radiologists) before and after AI-Thyroid assistance.

Results

The area under the receiver operating characteristic (AUROC) curve of AI-Thyroid was 0.939. The AUROC, sensitivity, and specificity were 0.922, 87.0%, and 81.5% for test set 1 and 0.938, 89.9%, and 81.6% for test set 2. The AUROCs of AI-Thyroid did not differ significantly according to the prevalence of malignancies (>15.0% vs ≤15.0%, P = .226). In the simulated scenario, AI-Thyroid assistance changed the AUROC, sensitivity, and specificity from 0.854 to 0.945, from 84.2% to 92.7%, and from 72.9% to 86.6% (all P < .001) in group 1, and from 0.914 to 0.939 (P = .022), from 78.6% to 85.5% (P = .053) and from 91.9% to 92.5% (P = .683) in group 2. The interobserver agreement improved from moderate to substantial in both groups.

Conclusion

AI-Thyroid can improve diagnostic performance and interobserver agreement in thyroid cancer diagnosis, especially in less-experienced physicians.
Protective Factors and the Pathogenesis of Complications in Diabetes
Authors: Yu Marc Gregory , Gordin Daniel , Fu Jialin , Park Kyoungmin , Li Qian , King George Liang
Published: August 2023

Chronic complications of diabetes are due to myriad disorders of numerous metabolic pathways that are responsible for most of the morbidity and mortality associated with the disease. Traditionally, diabetes complications are divided into those of microvascular and macrovascular origin. We suggest revising this antiquated classification into diabetes complications of vascular, parenchymal, and hybrid (both vascular and parenchymal) tissue origin, since the profile of diabetes complications ranges from those involving only vascular tissues to those involving mostly parenchymal organs. A major paradigm shift has occurred in recent years regarding the pathogenesis of diabetes complications, in which the focus has shifted from studies on risks to those on the interplay between risk and protective factors. While risk factors are clearly important for the development of chronic complications in diabetes, recent studies have established that protective factors are equally significant in modulating the development and severity of diabetes complications. These protective responses may help explain the differential severity of complications, and even the lack of pathologies, in some tissues. Nevertheless, despite the growing number of studies on this field, comprehensive reviews on protective factors and their mechanisms of action are not available. This review thus focused on the clinical, biochemical, and molecular mechanisms that support the idea of endogenous protective factors, and their roles in the initiation and progression of chronic complications in diabetes. In addition, this review also aimed to identify the main needs of this field for future studies.
Wnt and BMP signalling direct anterior–posterior differentiation in aggregates of mouse embryonic stem cells
Authors: Amel Atoosa , Rabeling Alexa , Rossouw Simoné , Goolam Mubeen
Published: August 2023

Stem-cell-based embryo models have allowed greater insight into peri-implantation mammalian developmental events that are otherwise difficult to manipulate due to the inaccessibility of the early embryo. The rapid development of this field has resulted in the precise roles of frequently used supplements such as N2, B27 and Chiron in driving stem cell lineage commitment not being clearly defined. Here, we investigate the effects of these supplements on embryoid bodies to better understand their roles in stem cell differentiation. We show that Wnt signalling has a general posteriorising effect on stem cell aggregates and directs differentiation towards the mesoderm, as confirmed through the upregulation of posterior and mesodermal markers. N2 and B27 can mitigate these effects and upregulate the expression of anterior markers. To control the Wnt gradient and the subsequent anterior versus posterior fate, we make use of a BMP4 signalling centre and show that aggregates in these conditions express cephalic markers. These findings indicate that there is an intricate balance between various culture supplements and their ability to guide differentiation in stem cell embryo models.
Region-specific reversal of epidermal planar polarity in the rosette fancy mouse
Authors: Cetera Maureen , Sharan Rishabh , Hayward-Lara Gabriela , Phillips Brooke , Biswas Abhishek , Halley Madalene , Beall Evalyn , vonHoldt Bridgett , Devenport Danelle
Published: August 2023

The planar cell polarity (PCP) pathway collectively orients cells with respect to a body axis. Hair follicles of the murine epidermis provide a striking readout of PCP activity in their uniform alignment across the skin. Here, we characterize, from the molecular to tissue-scale, PCP establishment in the rosette fancy mouse, a natural variant with posterior-specific whorls in its fur, to understand how epidermal polarity is coordinated across the tissue. We find that rosette hair follicles emerge with reversed orientations specifically in the posterior region, creating a mirror image of epidermal polarity. The rosette trait is associated with a missense mutation in the core PCP gene Fzd6, which alters a consensus site for N-linked glycosylation, inhibiting its membrane localization. Unexpectedly, the Fzd6 trafficking defect does not block asymmetric localization of the other PCP proteins. Rather, the normally uniform axis of PCP asymmetry rotates where the PCP-directed cell movements that orient follicles are reversed, suggesting the PCP axis rotates 180°. Collectively, our multiscale analysis of epidermal polarity reveals PCP patterning can be regionally decoupled to produce posterior whorls in the rosette fancy mouse.
An Exercise Intervention for South Asian Mothers with Risk Factors for Diabetes
Authors: Kandula Namratha R. , Dave Swapna S. , De Chavez Peter John D. , Marquez David X. , Bharucha Himali , Mammen Shinu M. , Dunaif Andrea , Ackermann Ronald T. , Kumar Santosh , Siddique Juned
Published: August 2023

South Asians (Indians, Pakistanis, Bangladeshis, Sri Lankans, Nepalis, and Bhutanese) in the United States have a very high prevalence of type 2 diabetes mellitus (DM). This pilot study evaluated a culturally tailored exercise intervention among South Asian immigrant mothers with DM risk factors. Through an academic–community partnership, South Asian women with risk factors for DM and who had at least one child between 6 and 14 yr were enrolled into this single-arm study. The intervention for the mothers included 16 wk of twice weekly exercise classes, self-monitoring with activity trackers, goal setting, and classes on healthy eating. Based on prior community-based participatory research, children were offered exercise classes during the mothers' classes. The primary efficacy outcomes were change in mothers' moderate/vigorous physical activity and body weight pre- and postintervention (16 wk). Program adherence, clinical, and psychosocial outcomes were measured. A qualitative process evaluation was conducted to understand participant perspectives. Participants' (n = 30) average age was 40 yr (SD, 5), 57% had a high school education or less, and all were overweight/obese. At baseline, women were not meeting the recommended physical activity guidelines. Overall, participants attended 75% of exercise classes. Compared with baseline, participants' weight decreased by 3.2 lb (95% confidence interval, −5.5 to −1.0) postintervention. Among women who attended at least 80% of classes (n = 17), weight change was −4.8 lb (95% confidence interval, −7.7 to −1.9). Change in accelerometer-measured physical activity was not significant; however, exercise-related confidence increased from baseline (P < 0.01). Women described multiple physical and psychosocial benefits from the intervention. In conclusion, this pilot study suggests that a culturally tailored exercise intervention that included exercise classes for children was feasible and had physical and psychosocial benefits in South Asian mothers with risk factors for DM.
The Cognitive Benefits of Exercise in Youth
Authors: Diamond Alex B.
Published: August 2023

As our schools and children struggle to meet ever-changing and mandated academic standards, challenges in the time spent on physical activity continue to arise. On the other hand, however, we continue to face a global climate mired in the midst of an obesity epidemic. It is widely accepted that the health benefits of exercise are wide-ranging and powerful. It appears that cognitive function and academic achievement are additional realms beyond the physical where exercise is beneficial. The school setting presents a unique public health opportunity to enact change on a variety of levels. As sports medicine and exercise specialists, we need to support efforts that increase access to quality physical fitness across the board for all children.
The Practice of Sport in Multiple Sclerosis: Update
Authors: Donze Cecile , Massot Caroline , Hautecoeur Patrick , Cattoir-Vue Helene , Guyot Marc-Alexandre
Published: August 2023

The practice of sport by multiple sclerosis patients has long been controversial. Recent studies, however, show that both sport and physical activity are essential for these patients. Indeed, they help to cope with the effects of multiple sclerosis, such as fatigue, reduced endurance, loss of muscle mass, and reduction of muscle strength. The beneficial effects of physical activity on these patients have been underlined in several studies, whereas those of practicing sport have been the subject of fewer evaluations and assessments. The aim of this update is to report on the effects of sport on multiple sclerosis patients. The benefits of sport have been demonstrated in several studies. It helps multiple sclerosis patients to increase their balance, resistance to fatigue, mobility and quality of life. Several biases in these studies do not enable us to recommend the practice of some of these sports on a routine basis.
Physical Activity Counseling in College Students
Authors: Wilson Oliver W.A. , Bopp Christopher M. , Papalia Zack , Bopp Melissa
Published: August 2023

Many college students are insufficiently physically active, and health care practitioner consultations represent an opportunity to provide at risk students with physical activity counseling (PAC). This study examined whether any demographic or physiological variables differentiated those who had received PAC and those who did not. An objective fitness assessment and survey collected data from college students concerning the following: demographics; body composition; aerobic fitness; cholesterol, lipid, and glucose levels; muscular endurance; physical activity (PA) levels; health care and PAC; PA information sources; and depression. Parametric and nonparametric techniques were used to examine differences between those who did and did not receive PAC, by location of counseling, and between those who did and did not report depressive symptoms. Rates of PAC were high, with only total cholesterol differentiating those who did and did not receive PAC. Study design prevented the determination of whether students or health care providers initiated PAC and what form of PAC was provided. Vigorous PA was significantly lower among those who reported mental health–related symptoms. Findings suggest a lack of targeted PAC among the least active, least fit, or most overweight/obese. Further investigation is warranted on the use of PAC at campus health services. In particular, the initiation of PAC, the PAC techniques/strategies used by physicians, and the short- and long-term effectiveness of PAC on PA and associated health outcomes. Barriers to student health care center physicians providing PAC also require further investigation, as does the effectiveness of any PAC and any support provided by physical fitness professionals that students may be referred to in both the short and long term.
Effects of Two Different Recovery Postures during High-Intensity Interval Training
Authors: Michaelson Joana V. , Brilla Lorrie R. , Suprak David N. , McLaughlin Wren L. , Dahlquist Dylan T.
Published: August 2023

The purpose of this study was to examine the effects of two different recovery postures, hands on head (HH) and hands on knees (HK), as a form of immediate recovery from high-intensity interval training (HIIT). Twenty female Division II varsity soccer players (age = 20.3 ± 1.1 yr, body mass index = 22.4 ± 1.80 kg·m−2) completed two experimental trials in a randomized, counterbalanced order. Each trial consisted of four intervals on a motorized treadmill consisting of 4 min of running (4 × 4) at 90%–95% HRmaxwith 3 min of passive recovery between each interval. HR recovery was collected during the first 60 s of each recovery, where volume of carbon dioxide (V̇CO2) and tidal volume (VT) were recorded each minute during the 3-min recovery period. Results showed an improved HR recovery (P< 0.001), greater VT(P= 0.008), and increased V̇CO2(P= 0.049), with HK (53 ± 10.9 bpm; 1.44 ± 0.2 L·min−1, 1.13 ± 0.2 L·min−1) compared with HH (31 ± 11.3 bpm; 1.34 ± 0.2 L·min−1, 1.03 ± 0.2 L·min−1). These data indicate that HK posture may be more beneficial than the advocated HH posture as a form of immediate recovery from high-intensity interval training.
A 2-yr Biomechanically Informed ACL Injury Prevention Training Intervention in Female Field Hockey Players
Authors: Weir Gillian , Alderson Jacqueline A. , Elliott Bruce C. , Lee Shina , Devaprakash Daniel , Starre Kate , Goodman Carmel , Cooke Jennifer , Rechichi Claire , Armstrong Josh , Jackson Ben , Donnelly Cyril J.
Published: August 2023

Purpose

Anterior cruciate ligament (ACL) injury prevention programs have been shown to have mixed success in reducing injury rates, raising the question whether these programs are effectively targeting biomechanical mechanisms of injury. The current study examined the efficacy of a biomechanically informed ACL injury prevention training program in reducing injury risk and injury incidence and investigated its effect on athletic performance.

Participants

Twenty-six elite female field hockey players participated in this study.

Methods

Athletes participated in a 2-yr injury prevention training program. Injury incidence (i.e., lower limb and ACL) and athletic performance (i.e., strength, speed, and aerobic power) were measured during a control season and after two intervention seasons. Biomechanical ACL injury risk factors were recorded during unplanned sidestepping at baseline and after intensive (9 wk: 4 × 20 min·wk−1) and maintenance (16 wk: 3 × 10 min·wk−1) training phases for a subset of athletes (n= 17).

Results

Training was effective in reducing ACL and lower limb injury incidence after the 2-yr program, where zero ACL injuries occurred after implementation (vs 0.4 per 1000 player hours in the control year). High-risk athletes reduced their peak knee valgus moments by 30% (P= 0.045) and demonstrated improvements in desirable muscle activation strategies after intensive training. The majority of benefits elicited in intensive training were retained during the maintenance phase. One-repetition max strength, beep test scores, and sprint times improved or were maintained over the 2-yr intervention period.

Conclusions

Biomechanically informed injury prevention training was successful in reducing both biomechanical ACL injury risk factors and ACL injury incidence while maintaining and/or improving athletic performance. It is important to consider the biomechanical mechanisms of injury when designing injury prevention programs.
Mediators of a 12-Month Change in Physical Activity in Ethnically Diverse Sample of Postpartum Women
Authors: Albright Cheryl L. , Wilkens Lynne R. , Saiki Kara , White Kami K. , Steffen Alana D.
Published: August 2023

Understanding theoretically derived social and behavioral mediators of long-term increases in physical activity (PA) in a vulnerable population at risk for being underactive is needed to inform future research, clinical applications, and public health efforts. This is an analysis of potential mediators of an intervention that increased long-term (12-month) moderate to vigorous physical activity (MVPA) in postpartum (2–12 months) women in a randomized trial, using a longitudinal analysis. Healthy, underactive (i.e., not meeting national guidelines for MVPA) women (n= 311; mean age = 32 ± 5.6 yr, 85% minorities) with infants (mean age: 5.7 ± 2.8 months) were randomly assigned to either a tailored eHealth condition consisting of personalized telephone counseling plus access to a website tailored to new mothers’ MVPA issues or to a standard MVPA materials-only website. MVPA was assessed via surveys completed at baseline, then 6 and 12 months later. Theoretically derived mediators included social support for MVPA, self-efficacy to increase MVPA, barriers to increasing MVPA, and benefits of increasing MVPA. All mediators, except benefits, improved over the 12 months in the tailored eHealth condition. The tailored condition’s effect on increasing MVPA from 6 to 12 months was mediated by an increase in social support from baseline to 6 months. No other hypothesized mediators were significant. Our results demonstrated that learning strategies to increase social support for MVPA was instrumental in new mothers’ increase in MVPA over a 12-month intervention. During this brief but impactful life stage, where the focus can understandably be on her baby, being able to elicit support from friends and family may facilitate women’s efforts to focus on their own needs with respect to MVPA.

Trial Registration: Clinical Trials.gov number: NCT00810342.
A Faith-Integrated Physical Activity Intervention and Cardiometabolic Risk in African American Women
Authors: Hornbuckle Lyndsey M. , Gizlice Ziya , Heil Daniel P. , Whitt-Glover Melicia C.
Published: August 2023

Purpose

This study aimed to determine the effects of a 10-month secular (SEC) versus faith-integrated (FI) community-based physical activity (PA) intervention on cardiometabolic risk factors in low active, African American women.

Methods

Participants (age, 55.4 ± 11.6 yr; body mass index [BMI], 36.0 ± 7.9 kg·m−2; average baseline steps per day, 3807 ± 1250) from a larger study (n = 418) participated in a substudy to measure cardiometabolic disease indicators (primary outcomes) and PA (secondary outcomes) pre- and postintervention (SEC, n = 42; FI, n = 43). Height, weight, waist and hip circumferences, resting blood pressure, hemoglobin A1c, average steps per day, sedentary behavior, light-intensity physical activity, and moderate- to vigorous-intensity physical activity were acquired at baseline and 10 months. Multivariate generalized linear mixed models that included churches as a random effect were used to compare mean changes in outcomes at 10 months between the two study groups (α = 0.05).

Results

The FI group showed significant time effects for weight (93.4 ± 2.4 to 92.2 ± 2.3 kg), BMI (35.7 ± 1.0 to 35.3 ± 1.0 kg·m−2), and waist circumference (106.9 ± 2.2 to 103.8 ± 2.5 cm), whereas the SEC group had a significant time effect for hip circumference (121.6 ± 1.9 to 119.9 ± 1.7 cm). There were no time effects in either group for blood pressure, hemoglobin A1c, steps per day, sedentary time, or moderate- to vigorous-intensity physical activity. FI significantly decreased light-intensity physical activity in both 1-min activity bouts (641 ± 13 to 588 ± 16 min·d−1) and 10-min bouts (536 ± 11 to 479 ± 15 min·d−1). There were no significant differences between SEC and FI for any variable.

Conclusions

The improvements in body weight, BMI, and waist circumference shown after the FI intervention could have long-term implications on cardiometabolic health, particularly if exercise is continued. Further research is needed to examine the effects of culturally relevant interventions on chronic disease indicators in African American women, particularly those established as high risk for cardiometabolic disease.

ClinicalTrials.gov Identifier: NCT00991731
O direito à espera da lei
Authors: Tácito Caio
Published: August 2023

1 - Eficácia da norma constitucional. 2 - Eficácia imediata e eficáciadiferida. 3 - Procedimentos especiais sobre inércia legislativa:mandado de injunção e ação de inconstitucionalidade por omlssao.4 - Jurisprudência do Supremo Tribunal Federal. 5 - Mandadode injunção e injunction.
Funcionário público - Função de assessoramento superior - Estabilidade
Authors: Mello Celso de
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Concurso público - Ampla defesa
Authors: Sobral Geraldo
Published: August 2023

Superior Tribunal de Justiça
Extradição - Delito político - Direito de asilo
Authors: Mello Celso de
Published: August 2023

Supremo Tribunal Federal
Mandado de segurança - Relator - Indeferimento liminar
Authors: Mello Celso de
Published: August 2023

Supremo Tribunal Federal
Desenvolvimento urbano no Brasil (aspectos jurídicos)
Authors: Pessoa Álvaro
Published: August 2023

1. Introdução. 2. O problema fundiário. 3. Regras de desenvolvimento urbano. - 4. O município brasileiro e a urbanização. 5. O trato jurídico no problema fundiário urbano. 6. Debates.
Taxa - Fato gerador - Poder de polícia
Authors: Peixoto Cunha
Published: August 2023

Supremo Tribunal Federal
Isenção fiscal - Zona Franca - Exportação
Authors: Guerra Cordeiro
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Acumulação de cargos - Demissão
Authors: Catunda Moacir
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Absolvição criminal - Exame dos motivos
Authors: Velloso Carlos Mário
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Aposentadoria - Direito adquirido
Authors: Branco Francisco de Salles Mourão
Published: August 2023

Tribunal de Contas da União
Confisco - Excesso - Restituição
Authors: Queiroz Cid Heráclito de
Published: August 2023

Ministério da Fazenda
Tribunal de Contas - Câmara Municipal - Auditoria - Resistência
Authors: Meirelles Hely Lopes
Published: August 2023

- O Tribunal de Contas pode realizar auditoria, a qualquer tempo, em órgão de despesa de Câmara Municipal, sem ofensa ao princípio da independência do Poder Legislativo.- Havendo oposição e resistência à auditoria, poderá o Tribunal de Contas requisitar força policial ou pedir a intervenção do Estado no Legislativo local, sem prejuízo da responsabilidade pelo crime de desobediência.
Mandado de segurança - Federação - Autonomia estadual
Authors: Guerra Cordeiro
Published: August 2023

Supremo Tribunal Federal
Poder de polícia - Congresso Nacional - Acesso público
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Município - Intervenção - Corrupção
Authors: Abreu Leitão de
Published: August 2023

Supremo Tribunal Federal
Imposto sobre operações financeiras - Anualidade - Legalidade
Authors: Ribeiro Justino
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Vantagem - Isonomia
Authors: Guerra Cordeiro
Published: August 2023

Supremo Tribunal Federal
Exercício profissional - Incompatibilidade - Ordem dos Advogados
Authors: Braz Torreão
Published: August 2023

Tribunal Federal de Recursos
Organização judiciária - Iniciativa de lei - Poder de emenda
Authors: Munoz Soares
Published: August 2023

Supremo Tribunal Federal
Contribuição - Fornecedores de cana - Destinação
Authors: Brito Washington Bolivar de
Published: August 2023

Tribunal Federal de Recursos
Associação de utilidade pública (conceito - ato declaratório)
Authors: Gasparini Diogenes
Published: August 2023

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Funcionário público - Remuneração - Aposentadoria
Authors: Aragão Newton Mendes de
Published: August 2023

Departamento Administrativo do Serviço Público
Contrato administrativo - Aprovação - Dispensa
Authors: Cruz Paulo Silva da
Published: August 2023

Tribunal de Contas da União
Funcionário público - Professores estaduais - Salário mínimo
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Progressão funcional - Requisitos
Authors: Aragão Newton Mendes de
Published: August 2023

Departamento Administrativo do Serviço Público
Emenda Constitucional nº 22, leis, decretos-lei e decretos (1982)
Authors: Desconhecido Autor
Published: August 2023

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Lei - Representação - Medida cautelar
Authors: Corrêa Oscar
Published: August 2023

Supremo Tribunal Federal
Acumulação - Dispensa - Indenização
Authors: Passarinho Aldir
Published: August 2023

Supremo Tribunal Federal
Estrangeiro - Naturalização - Bom procedimento
Authors: Leite Evandro Gueiros
Published: August 2023

Tribunal Federal de Recursos
Responsabilidade do estado - Caderneta de poupança - Falsificação
Authors: Cândido José
Published: August 2023

Tribunal Federal de Recursos
Ministério Público - Remuneração - Teto
Authors: Luz Ivan
Published: August 2023

Tribunal de Contas da União
Sociedade de economia mista - Diretores-empregados - "Opção"
Authors: Branco Francisco de Salles Mourão
Published: August 2023

Tribunal de Contas da União
Imposto - Denúncia espontânea - Parcelamento
Authors: Velloso Carlos Mário
Published: August 2023

Tribunal Federal de Recursos
Poder de polícia - Salvo-conduto - Trottoir
Authors: Guerra Cordeiro
Published: August 2023

Supremo Tribunal Federal
Previdência social - Tempo de serviço - Regulamento
Authors: Silva José Pereira da
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Tribunal de Contas - Tempo de serviço
Authors: Ferreira Filho Manoel Gonçalves
Published: August 2023

1. Contagem de tempo de mandato parlamentar. 2. O estatutoconstitucional do servidor público. 3 O período de mandato parlamentarcomo tempo de serviço público. 4. Lei interpretativa, retroatividadee jus superveniens.
Imposto territorial rural - Serviço de lançamento e arrecadação - Retenção de parcela
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Aposentadoria - Prescrição
Authors: Passarinho Aldir
Published: August 2023

Supremo Tribunal Federal
Magistrado - Remoção - Lista tríplice
Authors: Resek Francisco
Published: August 2023

Supremo Tribunal Federal
Mandado de segurança - Bolsa de valores - Compra e venda de ações
Authors: Passarinho Aldir
Published: August 2023

Supremo Tribunal Federal
Código de conduta das transnacionais e a lei de S.A.
Authors: Lamy Filho Alfredo
Published: August 2023

1. Considerações preliminares. 2. Estrutura jurídica das transnacionais.3. O poder de controle. 4. A legislação brasileira. 5. Conclusões.
Falta disciplinar - Prescrição - Ordem dos Advogados
Authors: Brito Washington Bolivar de
Published: August 2023

Tribunal Federal de Recursos
Trabalhador rural - Concessão de terras - Constitucionalidade
Authors: Muñoz Pedro Soares
Published: August 2023

Supremo Tribunal Federal
Suspensão da intervenção - Abuso de poder - Compensação de tarifas
Authors: Tácito Caio
Published: August 2023

- Importa abuso de poder a imposição de condições para a suspensão de intervenção.- Agravamento das condições pelo órgão executor.- Serviço pelo custo e sistema de compensação de tarifas.
Estado de direito e estado legal
Authors: Ferreira Filho Manoel Gonçalves
Published: August 2023

1. Questões preliminares. 2. A limitação do poder pelo direito. 3. Os princípios do estado de direito. 4. O estado legal. 5. A renovação do estado de direito
Taxa - Contribuição de melhoria - Inconstitucionalidade
Authors: Silveira Néri da
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Sindicância - Direito de defesa
Authors: Patterson William
Published: August 2023

Tribunal Federal de Recursos
Poder de polícia - Ato normativo - Filme nacional
Authors: Leitão Lauro
Published: August 2023

Tribunal Federal de Recursos
Formação, efeitos e extinção dos atos administrativos negociais
Authors: Meirelles Hely Lopes
Published: August 2023

1. Considerações gerais. 2. A formação dos atos negociais. 3. Osefeitos dos atos negociais. 4. A extinção dos atos negóciais. 5.Conclusões.
Taxa - Assistência educacional - Inconstitucionalidade
Authors: Muñoz Jorge Soares
Published: August 2023

Supremo Tribunal Federal
Isenção fiscal - Casa da Moeda - Concessionária de serviço público
Authors: Silveira Néri da
Published: August 2023

Supremo Tribunal Federal
Representação - Iniciativa - Procurador-Geral da República
Authors: Falcão Djaci
Published: August 2023

Supremo Tribunal Federal
Professor - Concurso público - Livre-docência
Authors: Raymundo Adhemar
Published: August 2023

Tribunal Federal de Recursos
Prescrição qüinqüenal - Fundo do direito - Actio Nata
Authors: Mayer Rafael
Published: August 2023

Supremo Tribunal Federal
Ensino - Receita vinculada - Emenda constitucional nº 24/83
Authors: Poletti Ronaldo Rebello de Britto
Published: August 2023

Presidência da República
Responsabilidade civil do estado - Caso fortuito - Militar
Authors: Freire José Carlos Soares
Published: August 2023

Departamento Administrativo do Serviço Público
Banco Central - Intervenção - Controle judicial
Authors: Tácito Caio
Published: August 2023

A intervenção administrativa em instituições financeiras é procedimento administrativo sujeito a controle judicial, pela via do mandado de segurança.
Funcionário público - Ato disciplinar - Mandado de segurança
Authors: Sobral Geraldo
Published: August 2023

Tribunal Federal de Recursos
Mandado de segurança - Sindicatos - Lei em tese
Authors: Falcão Djaci
Published: August 2023

Supremo Tribunal Federal
Bem público - Permissão de uso - Revogação
Authors: Pinheiro Helio
Published: August 2023

Tribunal Federal de Recursos
Autonomia municipal - Câmara de Vereadores - Pessoal da secretaria
Authors: Mayer Rafael
Published: August 2023

Supremo Tribunal Federal
União Federal - Investimentos - Empresas não controladas
Authors: Gonçalves Fernando
Published: August 2023

Tribunal de Contas da União
Evolução e ápice da crise constitucional-tributária
Authors: Nogueira Ruy Barbosa
Published: August 2023

1. Imposto, tirania, liberdade e progresso. 2. O reinado do Leão.3. Primeiras e imediatas providências. 4. A Federação e a tripartiçãode poderes hoje s6 no papel. 5. A atual pressão fiscal ad terrorem ead calamitatem do poder executivo nacional.
O poder judiciário na Constituição: uma proposta de reforma
Authors: Velloso Carlos Mário da Silva
Published: August 2023

1. O Poder Judiciário como guardião maior dos direitos e das garantiasconstitucionais. 2. Das garanti4S de independência do Poder Judiciário.3. A criação de Tribunais Superiores de Direito Público, de Direito Privado e de Direito Penal. 4. A proposta de reforma em termos globais: a instituição de Tribunais Superiores de Direito PÚblico, de Direito Privado e de Direito Penal. 5. Um pouco de direito comparado. 6. O sistema judiciário brasileiro na proposta aqui apresentada. O Supremo Tribunal Federal. 7. Conclusões.
Funcionário público - Acumulação - Fundação
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Constituição estadual - Lei complementar
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Vereador - Ato de ofício - Corrupção ativa
Authors: Corrêa Oscar
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Aposentadoria - Cassação
Authors: Bessone Darcy
Published: August 2023

Presidência da República
Imposto de renda - Hotéis - Isenção
Authors: Ferrante Miguel
Published: August 2023

Tribunal Federal de Recursos
Tribunal de Contas - Pensão - Registro
Authors: Bessone Darcy
Published: August 2023

Presidência da República
Empregado celetista - Aposentadoria - Contrato de trabalho
Authors: Guimarães Marcondes Mundim
Published: August 2023

Departamento Administrativo do Serviço Público
Polícia e poder de polícia
Authors: Cretella Júnior José
Published: August 2023

1. Segurança individual e polícia. 2. Conceito de polícia. 3. Elementosintegrantes do conceito de polícia. 4. Nossa definição de polícia. 5.Análise da definição de polícia. 6. Divisão da polícia. 7. Polícia administrativa. 8. Arbitrariedade e discricionariedade da ação policial.9. Polícia judiciária. 10. Polícia nas três esferas. 11. Ramos da políciaadministrativa. 12. Incidência da ação policial. 13. Poder "de" epoder "da" polícia. 14. Poder de polícia na doutrina brasileira. 15.Direito positivo e jurisprudência. 16. Poder de polícia, causa; polícia,conseqüência. 17. Limites ou barreiras do poder de polícia. 18. Conclusão e sugestão de lege ferenda.
Funcionário público - Iniciativa de lei - Concurso
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Poder legislativo - Criação de cargos - Vinculação de vencimentos
Authors: Miranda Decio
Published: August 2023

Supremo Tribunal Federal
Tribunal de Contas - Município - Controle externo
Authors: Silveira Néri da
Published: August 2023

Supremo Tribunal Federal
Considerações sobre o controle administrativo
Authors: Pondé Lafayette
Published: August 2023

1. Concessão; autorização; permissão. 2. Linguagem juridica. 3. Controleadministrativo: conceito. 4. Controle intersubjetivo e controleinterorgânico. 5. Controle externo e controle interno. 6. Controlehierárquico. 7. Controle substitutivo; avocação 8. Interesse públicorelevante.
Funcionário público - Aposentadoria - Tempo de serviço
Authors: Falcão Djaci
Published: August 2023

Supremo Tribunal Federal
Militar - Acumulação - Proibição
Authors: Pinheiro Helio
Published: August 2023

Tribunal Federal de Recursos
Ministério Público - Carreira - Provimento
Authors: Miranda Decio
Published: August 2023

Supremo Tribunal Federal
Decretos-leis e Decretos (1986)
Authors: Desconhecido Autor
Published: August 2023

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Imposto - Isenção - Correção monetária
Authors: Madeira Carlos
Published: August 2023

Supremo Tribunal Federal
Imposto sobre circulação de mercadorias - Diferimento - Produtos para exportação
Authors: Rezek Francisco
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Ato disciplinar - Motivação
Authors: Mayer Rafael
Published: August 2023

Supremo Tribunal Federal
Magistrado - Acumulação - Direito adquirido
Authors: Alves Moreira
Published: August 2023

Supremo Tribunal Federal
Justiça do Trabalho - Juiz togado - Advogado
Authors: Corrêa Oscar
Published: August 2023

Supremo Tribunal Federal
Ato administrativo - Exame dos motivos - Pena disciplinar
Authors: Thibau Carlos
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Vencimentos - Paridade
Authors: Mayer Rafael
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Aposentadoria - Tempo de serviço
Authors: Trindade Francisco Dias
Published: August 2023

Tribunal Federal de Recursos
Médico militar - Acumulação - Direito à nomeação
Authors: Borja Célio
Published: August 2023

Supremo Tribunal Federal
Associação recreativa - Registro profissional - Piscina
Authors: Ribeiro Antônio de Pádua
Published: August 2023

Tribunal Federal de Recursos
Autarquia - Fazenda Pública - Privilégio
Authors: Brito Washington Bolivar de
Published: August 2023

Tribunal Federal de Recursos
Poder de polícia - Trânsito - Abuso de poder
Authors: Dantas José
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Direito de certidão - Finalidade
Authors: Ramos J. Saulo
Published: August 2023

Presidência da República
Empréstimo compulsório - Decreto-lei - Constitucionalidade
Authors: Queiroz Cid Heráclito de
Published: August 2023

Ministério da Fazenda
Conselho profissional - Autarquia - Acumulação
Authors: Marinho Laerte José
Published: August 2023

Tribunal de Contas de União
Bases constitucionais do direito administrativo
Authors: Tácito Caio
Published: August 2023

1. Relação entre o direito constitucional e o direito administrativo.2. Orbita própria da Constituição. 3'. Constituições no Estadoliberal e no Estado de bem-estar social. 4. Presença atual do direitoadministrativo.
Ato administrativo - Poder discricionário - Censura
Authors: Velloso Carlos M.
Published: August 2023

Tribunal Federal de Recursos
Fundação - Abuso de direito - Disregard doctrine
Authors: Marinho Laerte José
Published: August 2023

Tribunal de Contas da União
Militar - Proventos - Prescrição
Authors: Ferreira Sergio de Andréa
Published: August 2023

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Funcionário público - Acumulação - Opção
Authors: Brito Washington Bolivar de
Published: August 2023

Tribunal Federal de Recursos
Funcionário público - Concurso - Limite de idade
Authors: Sanches Sydney
Published: August 2023

Supremo Tribunal Federal
Tribunal de Contas - Prestação de contas - Lei estadual
Authors: Silveira Néri da
Published: August 2023

Supremo Tribunal Federal
Desapropriação - Interesse social - Revenda
Authors: Madeira Carlos
Published: August 2023

Supremo Tribunal Federal
Desapropriação - Reforma agrária - Empresa rural
Authors: Sanches Sydney
Published: August 2023

Supremo Tribunal Federal
Tribunal de Contas - Reforma - Revisão
Authors: Ramos J. Saulo
Published: August 2023

Presidência da República
Funcionário público - Aposentadoria - Limitação de valor
Authors: Brito Washington Bolivar de
Published: August 2023

Tribunal Federal de Recursos
Extradição - Crime público - Tribunal de exceção
Authors: Borja Célio
Published: August 2023

Supremo Tribunal Federal
Imposto de renda - Pessoa física - Retenção na fonte
Authors: Doniak Jimir S.
Published: August 2023

Secretaria da Receita Federal
Funcionário público - Concurso - Enquadramento
Authors: Borja Célio
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Nomeação - Concurso
Authors: Moreira José Carlos Barbosa
Published: August 2023

Tribunal de Justiça do Estado do Rio de Janeiro
Universidade - Fundação - Direito de ação
Authors: Patterson William
Published: August 2023

Tribunal Federal de Recursos
Licitação - Assembléia legislativa - Direito de informação
Authors: Rezek Francisco
Published: August 2023

Supremo Tribunal Federal
Imposto de renda - Rendimentos do trabalho - Retenção pelos estados
Authors: Gallotti Luiz Octávio
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Salário mínimo - Vinculação
Authors: Passarinho Aldir
Published: August 2023

Supremo Tribunal Federal
Estado-membro - Bloqueio de contas bancárias - Desvio de poder legislativo
Authors: Tácito Caio
Published: August 2023

- A indisponibilidade de contas bancárias do estodo-membro esuas empresas mediante deüberaçõo do Banco Central é inconstitucionalpor ofensa ao principio da autonomia peculiar ao sistema federativo.Importa desvio do Poder Legislativo decreto-lei que se utiüze do bloqueio de contas bancárias como meio de cobrrmça regressiva de aval a emprútimos externos. Inconstitucionalidade do art. 7º- do Decreto-lei nº 2.169/84.
Funcionário público - Efetivação - Concurso público
Authors: Silveira Néri da
Published: August 2023

Supremo Tribunal Federal
Governador substituto - Subsídio vitalício - Inconstitucionalidade
Authors: Corrêa Oscar Dias
Published: August 2023

Supremo Tribunal Federal
Militar - Equiparação de vencimentos - Iniciativa
Authors: Madeira Carlos
Published: August 2023

Supremo Tribunal Federal
Prescrição - Suspensão - Silêncio da administração
Authors: Madeira Carlos
Published: August 2023

Supremo Tribunal Federal
Instituição de assistência social - Fundação - Imunidade tributária
Authors: Gallotti Luiz Octávio
Published: August 2023

Supremo Tribunal Federal
Militar - Punição indireta - Garantia de defesa
Authors: Leite Evandro Gueiros
Published: August 2023

Tribunal Federal de Recursos
Ação popular - Perdas e danos - Correção monetária
Authors: Borja Célio
Published: August 2023

Supremo Tribunal Federal
Juros reais - Crime de usura - Lei complementar
Authors: Martins Ives Grandra da Silva
Published: August 2023

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A Constituição de 1988 e o Tribunal de Contas da União
Authors: Souza Luciano Brandão Alves de
Published: August 2023

1. Introdução. 2 O TCU e a Constituinte. 3. As novas competências do Tribunal. 4. Um controle mais abrangente de pessoal. 5. Um mandamento inovador. 6 A descentralização de recursos. 7. O Tribunal e o Poder Legislativo: ação conjugada. 8. A nova composição do Tribunal 9. Reforçando os sistemas de controle interno. 10. O cidadão: agente controlador. 11. O Ministério Público junto ao TCU. 12. Uma nova Lei Orgânica para o Teu. 13. Um desafio com data marcada. 14. Conclusão.
Tributo - Multa administrativa - Desvio de poder
Authors: Passarinho Aldir
Published: August 2023

Supremo Tribunal Federal
Constituição de 1988 - Prisão administrativa - Inconstitucionalidade
Authors: Alves José Carlos Moreira
Published: August 2023

Supremo Tribunal Federal
Mandado de segurança - Legitimidade processual - Direito próprio
Authors: Vieira Jacy Garcia
Published: August 2023

Tribunal Federal de Recursos
Concessão de serviço público - Rescisão - Indenização
Authors: Madeira Carlos
Published: August 2023

Tribunal Federal de Recursos
Medidas provisórias, Leis e Decreto Legislativo (1989)
Authors: Desconhecido Autor
Published: August 2023

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Empresa pública - Autarquia - EMBRATUR
Authors: Cunha Jatir Batista da
Published: August 2023

Tribunal de Contas da União
Exportação de café - Contratos privados de administração - Publicidade
Authors: Tácito Caio
Published: August 2023

- Os contratos de exportação de café celebrados pelo Instituto Brasileirodo Café não são contratos administrativos. Sua eficácia independe depublicação no órgão oficial.
Funcionário público - Constituição de 1988 - Direitos e vantagens
Authors: Corazza Eloy
Published: August 2023

Secretaria de Recursos Humanos
Mandado de segurança - Medida liminar - Agravo
Authors: Sanches Sydney
Published: August 2023

Supremo Tribunal Federal
Desapropriação - Legitimidade - Desvio de finalidade
Authors: Sobral Geraldo
Published: August 2023

Superior Tribunal de Justiça
Correção monetária - Dívida agrária - Justa indenização
Authors: Vieira Jacy Garcia
Published: August 2023

Superior Tribunal de Justiça
Ação de inconstitucionalidade - Advogado-Geral da União - Curador da lei
Authors: Pertence José Paulo Sepúlveda
Published: August 2023

Supremo Tribunal Federal
Funcionário público - Disponibilidade remunerada - Proventos proporcionais
Authors: Silva Célio
Published: August 2023

Presidência da República