Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11–13 November 2018
Authors: Ahmed Niaz , Audebert Heinrich , Turc Guillaume , Cordonnier Charlotte , Christensen Hanne , Sacco Simona , Sandset Else Charlotte , Ntaios George , Charidimou Andreas , Toni Danilo , Pristipino Christian , Köhrmann Martin , Kuramatsu Joji B , Thomalla Götz , Mikulik Robert , Ford Gary A , Martí-Fàbregas Joan , Fischer Urs , Thoren Magnus , Lundström Erik , Rinkel Gabriel JE , Worp H Bart van der , Matusevicius Marius , Tsivgoulis Georgios , Milionis Haralampos , Rubiera Marta , Hart Robert , Moreira Tiago , Lantz Maria , Sjöstrand Christina , Andersen Grethe , Schellinger Peter , Kostulas Konstantinos , Sunnerhagen Katharina Stibrant , Keselman Boris , Korompoki Eleni , Purrucker Jan , Khatri Pooja , Whiteley William , Berge Eivind , Mazya Michael , Dippel Diederik WJ , Mustanoja Satu , Rasmussen Mads , Söderqvist Åsa Kuntze , Escudero-Martínez Irene , Steiner Thorsten 
Published: September 2019

The purpose of the European Stroke Organisation–Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may be implemented into clinical routine. The meeting started 22 years ago as Karolinska Stroke Update, but since 2014 it is a joint conference with European Stroke Organisation. Importantly, it provides a platform for discussion on the European Stroke Organisation guidelines process and on recommendations to the European Stroke Organisation guidelines committee on specific topics. By this, it adds a direct influence from stroke professionals otherwise not involved in committees and work groups on the guideline procedure. The discussions at the conference may also inspire new guidelines when motivated. The topics raised at the meeting are selected by the scientific programme committee mainly based on recent important scientific publications. This year’s European Stroke Organisation–Karolinska Stroke Update Meeting was held in Stockholm on 11–13 November 2018. There were 11 scientific sessions discussed in the meeting including two short sessions. Each session except the short sessions produced a consensus statement ( Full version with background, issues, conclusions and references are published as web-material and at www.eso-karolinska.org and http://eso-stroke.org ) and recommendations which were prepared by a writing committee consisting of session chair(s), scientific secretary and speakers. These statements were presented to the 250 participants of the meeting. In the open meeting, general participants commented on the consensus statement and recommendations and the final document were adjusted based on the discussion from the general participants Recommendations (grade of evidence) were graded according to the 1998 Karolinska Stroke Update meeting with regard to the strength of evidence. Grade A Evidence: Strong support from randomised controlled trials and statistical reviews (at least one randomised controlled trial plus one statistical review). Grade B Evidence: Support from randomised controlled trials and statistical reviews (one randomised controlled trial or one statistical review). Grade C Evidence: No reasonable support from randomised controlled trials, recommendations based on small randomised and/or non-randomised controlled trials evidence.