bluuebunny/crossref_metadata_2025 huggingface dataset:
Bots influence opinion dynamics without direct human-bot interaction: the mediating role of recommender systems
Authors: Pescetelli Niccolo , Barkoczi Daniel , Cebrian Manuel
Published: March 2022

Bots’ ability to influence public discourse is difficult to estimate. Recent studies found that hyperpartisan bots are unlikely to influence public opinion because bots often interact with already highly polarized users. However, previous studies focused on direct human-bot interactions (e.g., retweets, at-mentions, and likes). The present study suggests that political bots, zealots, and trolls may affect people’s views indirectly via the mediating role of a platform’s content recommendation system, thus influencing opinions even in the absence of direct human-bot interaction. Using an agent-based opinion dynamics simulation, we isolated the effect of a single bot – representing 1% of nodes in a network – on the opinion formed by rational Bayesian agents after removing direct human-bot connections. We compare this experimental condition with an identical baseline condition where such a bot is absent. We used the same random seed in both simulations so that conditions remained identical except for the presence of the bot. Results show that, even in the absence of direct interactions, the mere presence of the bot is sufficient to shift the average population opinion. Virtually all nodes – not only nodes directly interacting with the bot – shifted towards more extreme opinions. Overall, these findings offer a proof of concept that bots and hyperpartisan accounts can influence population opinions not only by directly interacting with humans but also by secondary effects, such as shifting platforms’ recommendation engines’ internal representations. The mediating role of recommender systems creates indirect causal pathways of algorithmic opinion manipulation.
Investigation of the Cooperative Mode and Second Language Acquisition of Chinese Apology Words from the Perspective of Construction Grammar
Authors: Lun Xinyu
Published: March 2022

Based on the theory of construction grammar, this paper examines the cooperative mode and second language acquisition of Chinese apology words. It demonstrates the acquisition process and mechanism of Chinese apology words by second language learners. From the perspective of construction grammar, Chinese apology words are the intersection of form and meaning/function. There are frame structures and non-frame structures in the cooperative mode, and additionally, there are complete and omitted forms. The learner's output of apology words includes errors and correct usage. Errors include wrong coordinated mode selection, out-of-order coordination components, incomplete coordination components, and misuse of coordination components. The correct output refers to the cooperative model of the learner's apology words, including the location, usage, and selection of the components, which can be used accurately. The internal acquisition mechanism of these outputs is the learner's "coordination awareness" of apology words. The mastery of "coordination awareness" can be divided into levels and stages. There are three levels in StageⅠ, namely, no coordination awareness, preliminary coordination awareness and basic coordination awareness. StageII means that the learner has complete coordination awareness, which shows that the learner's acquisition of apology words is staged and hierarchical.
Culture Negative Sepsis after Pediatric Cardiac Surgery: Incidence and Outcomes
Authors: Gopalakrishnan Rajesh M , Nair Arjun R , Sudhakar Abish , Jayant Aveek , Balachandran Rakhi , Neema Praveen Kumar , Kumar Raman Krishna
Published: March 2022

Background: A significant proportion of children after cardiac surgery with clinical features of blood stream sepsis do not have a positive blood culture and are managed as presumed ‘culture negative sepsis (CNS)’. There is little information on outcomes of CNS early after pediatric cardiac surgery. We sought to describe the incidence, outcomes and antibiotic utilization pattern of culture negative sepsis in children undergoing cardiac surgery.Methods : 437 consecutive children who underwent cardiac surgery were studied. CNS was empirically defined as those in whom antibiotics were upgraded based on clinical and/or laboratory suspicion of blood stream sepsis with eventual negative blood culture. Outcomes were compared between three groups: normal controls, CNS and Culture Positive Sepsis (CPS).Results: Incidence of CNS was 16% (71/437). The mortality was highest in CPS group (10.7%, 3/29); intermediate for CNS (2.9%, 2/71) and least for the normal group (1.2%, 4/337). Similarly, duration of ventilation and intensive care unit (ICU) length of stay (in hours) was highest for CPS (116 [45-271]; 288 [156-444]), intermediate for CNS (63 [23-112]; 192 [120-288]) and least for the normal group (18 [6-28]; 72 [48-120]). Third-tier antibiotics were initiated for 27 (40%) with CNS and 23 (92%) with CPS. Although the mean antibiotic duration for CNS (6.3±3.0 days) was less than CPS (9.09±5.12); p=0.022, 27.3% of CNS received antibiotics for more than one week. Conclusion: The high incidence of CNS points towards the need for accurate biomarkers of bacterial sepsis after cardiac surgery. The relatively better outcomes of CNS merits consideration to rapidly de-escalate antibiotics for presumed sepsis after cardiac surgery.
Rates of oropharyngeal cancer continue to rise steeply amongst Australian men: continued emphasis on HPV vaccination, tobacco and alcohol control
Authors: Fan Ka Ming , Sprague Samuel , Zhang Ping , Ariyawardana Anura , Johnson Newell W.
Published: March 2022

Objective
To analyse trends in incidence of oropharyngeal cancers (OPC) across Australia from 1982 to 2017 with implications for prevention.
Methods
Data were obtained from the Australian Cancer Database (ACD) compiled at the Australian Institute of Health and Welfare (AIHW). Incidence rates of OPC were expressed per 100,000 population, age-standardized in accordance with WHO standard population. Joinpoint analyses are presented.
Results
A striking increase of age-standardised incidence rate (ASIR) of OPC by over 1.5 times from 1.86/100,000 in 1982 to 3.23/100,000 in 2017 was observed in men: the most significant rise was between 2007 and 2017 with an annual percentage change (APC) of + 5.24% (p < 0.001). Slow but gradual growth of ASIR from 0.38/100,000 in 1982 to 0.71/100,000 in 2017 was observed among women with a statistically significant APC of + 1.02% (p < 0.001). Statistically significant bimodal increasing trends of APC were also observed in total ASIR of OPC. Highest number of incident cases were found in patients aged 55 to 69 years old, accounting for 50.8% on average of all ages during each 7-year time period. Most common subsites affected were base of tongue (BOT) and “oropharynx” from 1982 to 2017.
Conclusion
OPC is rising rapidly across Australia, particularly in men. Whilst the national proportion of cases driven by HPV is not known, it is evident that vaccination is yet to have an impact. A substantial proportion of cases are, presumably, still driven by traditional alcohol and tobacco habits, mandating continued efforts at control of these risk factors.
The heterogeneous early illness courses of Korean patients with bipolar disorders – replication of the stage model
Authors: Lee Yejin , Lee Dongbin , Jung Hyewon , Cho Yunji , Baek Ji Hyun , Hong Kyung Sue
Published: March 2022

Background
Clinical staging of bipolar disorder requires application of real-world data, as the next step in hypothesis. This study used the staging model to analyze the long-term course of BD in Korean patients based on clinical features and treatment responses to map the progression of bipolar illness from the early phase after the onset of illness.
Methods
A total of 136 patients diagnosed with BD-I (n = 62) or BD-II (n = 74) were recruited. Their progressive stages were retrospectively evaluated. The multi-state model was used to calculate the probability of progression to each stage. We calculated the hazard ratio of covariates expected to influence different courses of BD. Using the Alda score, we compared the long-term response to mood stabilizers depending on the current stage.
Results
Several sub-populations showed a varied course during the first five years after the onset of illness, with 41.5% remaining in stage 2 and 53% progressing to higher stages with shortening of time for transition. The profile of patients with BD-II differed profile from BD-I, suggesting biologically distinct groups. The group with Obsessive-compulsive Disorder (OCD) had higher risk in relation to both recurrent course (stage 3a or 3b) and malignant course (stage 3c or 4). Early age of onset, shorter lifetime duration, older age at the start of medication, and poor response to lithium affect long-term therapeutic outcomes.
Conclusions
The staging model encompasses early to recurrent and chronic courses of BD. The stage progression pattern differed in BD-Ⅰ and BD-Ⅱ patients from the early phase. Previous findings related to long-term course of BD enabled expansion of model parameters.
Automated radiolabelling procedures for the preparation of OncoFAP-based radiopharmaceuticals for cancer imaging and therapy
Authors: Bartoli Francesco , Elsinga Philip , Nazario Luiza Reali , Zana Aureliano , Galbiati Andrea , Millul Jacopo , Migliorini Francesca , Cazzamalli Samuele , Neri Dario , Slart Riemer H.J.A. , Erba Paola Anna
Published: March 2022

FAP-targeted radiopharmaceuticals represent a breakthrough in cancer imaging and a viable option for therapeutic applications. OncoFAP, an ultra-high affinity ligand of FAP, has been recently discovered and clinically validated for PET imaging procedures in patients with solid malignancies. While more and more clinical validation is becoming available, the need for scalable and robust procedures for the preparation of this new class of radiopharmaceuticals continues to increase. In this article, we present the development of automated radiolabelling procedures with FASTlab 2 for the preparation of OncoFAP-based radiopharmaceuticals for cancer imaging and therapy. A new series of [68Ga]Ga-OncoFAP, [177Lu]Lu-OncoFAP and [18F]AlF-OncoFAP was produced with high-yields. Chemical and biochemical characterization after radiolabelling confirmed excellent stability, retention of high affinity for FAP and absence of radiolysis by-products. The in vivo biodistribution of [18F]AlF-OncoFAP-NOTA, a candidate for PET imaging procedures in patients, was assessed in mice bearing FAP-positive solid tumours. The product showed rapid accumulation in solid tumours, with an average of 6.6% ID/g one hour after systemic administration and excellent tumour-to-healthy organs ratio. We have established methodologies to efficiently produce an OncoFAP-based radiotheranostic pair in which [68Ga]Ga-OncoFAP-DOTAGA is used as a companion diagnostic of the targeted therapeutic agent [177Lu]Lu-OncoFAP-DOTAGA Objectives: We have developed simple, quick, safe and robust synthetic procedures for the preparation of theranostic OncoFAP-compounds based on Gallium-68, Lutetium-177 and Alluminium-Fluoride-18 using the commercially available FASTlab 2 synthesis module.
Men of refugee and migrant backgrounds resettled in Australia: A scoping review of sexual and reproductive health research
Authors: Mengesha Zelalem , Hawkey Alex , Baroundi Mazen , Ussher Jane , Perz Janette
Published: March 2022

Background
Australia’s National Men’s Health Strategy 2020–2030 identifies men from refugee and migrant backgrounds as priority groups for sexual and reproductive health (SRH) interventions due to their high risk of poor outcomes. Given the traditional focus of SRH research on women, the lack of SRH research focusing on refugee and migrant men is a significant gap to guide implementation of the strategy and future research into this topic. To provide a foundation for rectifying this omission, this review aimed to synthesise the available evidence on refugee and migrant men’s SRH needs, understanding, and experiences of accessing services after resettlement in Australia.
Methods
We conducted a systematic search of peer reviewed literature in PubMed, Scopus, PsyInfo and Embase. A WHO framework for operationalising sexual health and its relationship with reproductive health was used to map the identified studies. The socio-ecological framework was applied to thematically synthesise data extracted from individual studies and identify factors that influence the SRH of refugee and migrant men.
Results
We identified and included 38 papers (24 sexual health, 5 reproductive health, 3 intimate relationships, 2 cancer and 4 ‘other’). The majority of sexual health studies (16) were about sexually transmitted infections (STIs), mainly HIV (12), Hepatitis B (3), and safe sexual practices (1). Reproductive health studies focused on contraceptive counselling and provision (3), antenatal, intrapartum and postnatal care (1) and safe abortion care (1). We also identified several factors influencing refugee and migrant men’s SRH including a lack of access to SRH information at the individual level, language and communication barriers at the interpersonal level and stigma at the community level.
Conclusions
This review indicates that the SRH literature on refugee and migrant men lacks perspectives beyond STIs. The literature does not frame SRH as a human right rather follows a risk-based biomedical approach of health care keeping important aspects of SRH, such as gender-based violence and sexual pleasure, out of health services research. These identified gaps should be addressed to develop effective, equitable and gender sensitive SRH programs for refugee and migrant men in Australia.
Satellite retrieved stubble-burning activities in north-western India in 2021: Contribution to air pollution in Delhi
Authors: Govardhan Gaurav , Ambulkar Rupal , Kulkarni Santosh , Vishnoi Ashok , Yadav Praful , Choudhury B. Abida , Khare Manoj , Ghude Sachin D.
Published: March 2022

Stubble-burning in northern India is an important source of atmospheric particulate matter (PM) and trace gases, which significantly impact local and regional climate, in addition to causing severe health risks. Scientific research on assessing the impact of these burnings on the air quality over Delhi is still relatively sparse. The present study analyzes the satellite-retrieved stubble-burning activities in the year 2021, using the MODIS active fire count data for Punjab and Haryana, and assesses the contribution of CO and PM2.5 from such biomass-burning activities to the pollution load in Delhi. The analysis suggests that the satellite-retrieved fire counts in Punjab and Haryana were the highest among the last five years (2016–2021). Further, we note that the stubble-burning fires in the year 2021 are delayed by ~ 1 week compared to that in the year 2016. To quantify the contribution of the fires to the air pollution in Delhi, we use tagged tracers for CO and PM2.5 emissions from fire emissions in the regional air quality forecasting system. The modeling framework suggests a maximum daily mean contribution of the stubble-burning fires to the air pollution in Delhi in the months of October-November 2021 to be around 30–35%. The quantification of this contribution is critical from the crop-residue and air-quality management perspective for policymakers in the source and the receptors regions, respectively.
Acidic culture medium enhances secretion of myoglobin and GDF-15 in MCF-7 breast cancer cells– multiplex assay data
Authors: Worsley Catherine Mary , Veale Rob B , Mayne Elizabeth S
Published: March 2022

Metastatic breast cancer is one of the leading causes of cancer mortality worldwide. While many therapeutic strategies try to control and combat this disease, a better understanding of cellular communication within the acidic tumour microenvironment is needed to improve treatment success. Here we characterized the secretory profile of MCF-7 breast cancer cells in medium of physiological pH, and compared it to those cells treated with medium of 6.5 and 3.2. MCF-7 cells secreted IP-10, VEGF, EGF, FGF, G-CSF, GDF-15, and myoglobin at baseline. When treated with acidic medium, MCF-7 cells downregulated secretion of many of these factors, although myoglobin and GDF-15 were significantly increased at pH 6.5 (1hr) (p < 0.0001). This may provide a survival advantage to the tumour cells at slightly acidic pH. Further studies investigating the effects of acidosis on breast carcinoma cells are needed to understand both their autocrine and paracrine signaling functions in the tumour microenvironment.
The Rice Blast Resistance Gene Pid Family Has Been Strictly Diverged Into Indica And Japonica Subspecies
Authors: Chai Ruipeng , Wang Jinyan , Wang Xing , Wen Jianqiang , Liang Zhijian , Ye Xuemei , Zhang Yaling , Yao Yongxiang , Zhang Jianfu , Zhang Yihua , Wang Ling , Pan Qinghua
Published: March 2022

Background: Rice blast (causative agent the fungus Pyricularia oryzae) represents a major constraint over the productivity of one of the world’s most important staple foods. Genes encoding resistance have been identified in both the indica and japonica subspecies genepools and combining these within new cultivars represents a rational means of combating the pathogen.Results: In this research, a deeper allele mining was carried out on Pid-2, Pid-3, and Pid-4 by each of comprehensive FNP marker set in the three panels consisting of 70 indica and 58 japonica cultivars. Within Pid-2, three functional and one non-functional alleles were identified; the former were only identified in indica type entries. At Pid-3, four functional and one non-functional alleles were identified, and once again, all of the formers were present in indica type entries. However, the pattern of variation at Pid-4 was rather different: here, the five functional alleles uncovered were dispersed across the japonica type germplasm. Among all the 12 candidate functional alleles, both Pid2-ZS and Pid3-ZS were predominant. Furthermore, the resistance functions of both Pid2-ZS and Pid3-ZS were assured by transformation test. Conclusions: Profiting from merits of three comprehensive FNP marker sets, the study has validated that all three members of the Pid family have been strictly diverged into indica and japonica subspecies: Pid-2 and Pid-3 were defined as indica type resistance genes, and Pid-4 as japonica one. Rather limited genotypes of the Pid family have been effective in both indica and japonica rice groups, of which Pid2-ZS+Pid3-ZS has been central to the Chinese rice population.
Structure-Based Virtual Screening, Molecular Docking, Molecular Dynamics simulation of VEGF inhibitors for the clinical treatment of Ovarian Cancer
Authors: Mukherjee Sourav , Abdalla Mohnad , Yadav Manasi , Madhavi Maddala , Bhrdwaj Anushka , Khandelwal Ravina , Prajapati Leena , Panicker Aravind , Chaudhary Aashish , Al-Brakati Ashraf , Hussain Tajamul , Nayarisseri Anuraj , Singh Sanjeev Kumar
Published: March 2022

Vascular Endothelial Growth Factor (VEGF) and its receptor play an important role both in physiologic and pathologic angiogenesis, which is identified in ovarian cancer progression and metastasis development. The aim of the present investigation is to identify a potential Vascular Endothelial Growth Factor inhibitor which is playing a crucial role in stimulating the immunosuppressive microenvironment in tumour cells of the ovary and to examine for an effectiveness of identified inhibitor for the treatment of ovarian cancer using various in-silico approaches. 12 established VEGF inhibitors were collected from various literature. The compound AEE788 displays the great affinity towards the target protein as a result of docking study. AEE788 was further used for structure-based virtual screening in order to obtain a more structurally similar compound with high affinity. Among the 80 Virtual screened compounds, CID 88265020, explicates much better affinity than established compound AEE788. Based on Molecular Dynamics Simulation, pharmacophore and comparative toxicity analysis of both the best-established compound and the best virtual screened compound displayed a trivial variation in associated properties. The virtual screened compound CID 88265020 have a high affinity with the lowest re-rank score, and holds a huge potential to inhibit the VGFR and can be implemented for prospective future investigations in Ovarian Cancer.
Platelet is the early predictor of bronchopulmonary dysplasia in very premature infants: an observational cohort study
Authors: Wang Xiaoling , Ma Yan , Wang Shenghui , Dong Wenbin , Lei Xiaoping
Published: March 2022

Background: A previous study showed that the lungs are involved in the biogenesis of platelets (PLTs). Thus, the present study aimed to investigate the association between bronchopulmonary dysplasia (BPD), a chronic lung disease, and PLT parameters in very premature infants.Methods: The study subjects were premature infants with a gestational age of ≤ 30 weeks and birth weight of ≤1500 g in a preterm birth cohort study recruited between January 1, 2015, and August 31, 2019. BPD was defined as the need for oxygen supplementation more than 28 days after birth. The PLT count, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) level were compared between BPD and non-BPD infants. A generalized estimating equation model was used to adjust for confounding factors. A forward stepwise logistic regression model was used to calculate the adjusted odds ratio (OR) for thrombocytopenia in the BPD group. Receiver operating characteristic (ROC) curve analysis was performed to assess the predictive value of PLT count combined with gestational age (GA) and birth weight (BW) for BPD.Results: The final study subjects were 134 very premature infants, namely, 64 infants with BPD and 70 infants without BPD. The BPD infants had lower PLT counts (F=4.44, P=0.03) and PCT levels (F=12.54, P=0.00) than the non-BPD infants. However, the MPV (F=14.25, P=0.00) and PDW (F=15.04, P=0.00) were higher in the BPD group. After adjusting for potential confounding factors, the BPD infants had a higher risk of thrombocytopenia than the non-BPD infants (adjusted aOR 2.88, 95% CI 1.01-8.15), and the risk of BPD was increased in very premature infants with a PLT count ≤ 177*109/L (OR 4.74, 95% CI 1.93-11.62) at the end of the second week. In the multivariate predictive model, it was showed that the AUC area (0.85), sensitivity (0.88), specificity (0.70) and Youden index (0.58) are improved using PLT counts ≤ 177*109/L combined with GA and BW.Conclusions: Abnormal PLT parameters were observed in BPD infants, and a PLT count ≤ 177*109/L was a potential risk factor for the development of BPD in very premature infants.
The use of new technological processes and their impact on the assessment of energy efficiency measures in the region (on the example of reducing the negative environmental consequences of snow disposal in Russian cities)
Authors: Полетаев И.Ю.
Published: March 2022

Проблема повышения эффективности использования ископаемых видов топлива для большинства стран мира является ключевой и напрямую связана со снижением объема выбросов парниковых газов в результате антропогенной деятельности. В данной статье показана необходимость анализа как краткосрочных, так и перспективных затрат при планировании мероприятий по внедрению новых технологий в условиях всеобщего энергетического кризиса, изменения структуры мирового энергетического рынка на фоне угрозы экологической катастрофы в связи с глобальным потеплением климата планеты.

The problem of increasing the efficiency of the use of fossil fuels for most countries of the world is a key one and is directly related to the reduction of greenhouse gas emissions as a result of anthropogenic activities. This article shows the need to analyze both short-term and long-term costs when planning measures for the introduction of new technologies in the conditions of a general energy crisis, changes in the structure of the world energy market against the threat of environmental catastrophe due to global warming of the planet's climate.
Assessment of the main parameters of the intellectual potential of the science city - Кorolev in the concept of its safe development
Authors: Сафронова Е.С. , Суглобов А.Е.
Published: March 2022

В статье рассмотрен один из наукоградов - г. Королев, приведены характеристики его социально-экономического развития, рассмотрены элементы созданной инновационной инфраструктуры. Необходимость развития инновационной инфраструктуры и поддержки малого и среднего бизнеса для наукоградов обусловлена необходимостью технического перевооружения производства и стендовой базы, трансформации избыточной инфраструктуры градообразующих предприятий и организаций; развития эффективной кооперации востребованного инновационного малого и среднего бизнеса с крупными градообразующими предприятиями, привлечения новых малых предприятий в город. Рассматривая интеллектуальный потенциал, как способность осваивать и генерировать инновации, подчеркнута значимость воспроизводства кадрового потенциала высококвалифицированных рабочих и специалистов, закрепления молодых учёных и специалистов в научных организациях города, вовлечения детей в инновационную деятельность с помощью новых инновационных структур - кванториумов, популяризации востребованных градообразующими предприятиями рабочих профессий.

The article considers one of the science cities - Korolev, presents the hackterstics of its socio-economic development, considers the elements of the created innovative infrastructure. The need to develop innovative infrastructure and support small and medium-sized businesses for science is due to the need for technical re-equipment of production and the bench base, transformation from the everyday infrastructure of city-forming enterprises and organizations; development of effective cooperation of demanded innovative small and medium-sized businesses with large city-forming enterprises, attracting new small enterprises to the city. Considering the intellectual potential as the ability to master and generate innovation, the importance of reproducing the human resources potential of highly qualified workers and specialists, consolidating young scientists and specialists in scientific organizations of the city, involving children in innovative activities with the help of new innovative structures - quantorium, popularizing the professions demanded by city-forming enterprises.
Monitoring of the sustainable development of a territory
Authors: Чувашова М.Н.
Published: March 2022

В статье предлагаются рекомендации по мониторингу устойчивого развития территории для органов власти. Основная цель предлагаемого мониторинга связана с проведением исследований по социально-экономическому и экологическому развитию и планированию территорий с целью достижения устойчивого развития и повышения межрегиональной и внутрирегиональной пространственной связанности. Предложен алгоритм государственного мониторинга устойчивого развития территории. Результаты мониторинга могут быть использованы региональными властями для формулирования положений по достижению устойчивого развития территории в рамках формирования Стратегии социально-экономического развития региона.

The paper proposes a methodology for the formation of monitoring of sustainable development of a territory. The main goal of the proposed methodology is connected with conducting research on socio-economic and environmental development and planning of territories in order to achieve sustainable development and increase inter-regional and intra-regional connectivity of territories. The algorithm for state monitoring of the sustainable development of a territory is proposed. The monitoring results can be used by regional authorities to formulate provisions for achieving the sustainable development of a territory within the framework of formation the Strategy for the socio-economic development of a region.
Formation of a region's portfolio of investment projects
Authors: Ващенко Т.В. , Восканян Р.О.
Published: March 2022

Разработка и последовательная реализация инвестиционной стратегии региона выступает основой макроэкономической стабильности и повышает его инвестиционную привлекательность. В настоящей статье авторами предлагается алгоритм формирования портфеля инвестиционных проектов региона посредством ранжирования на две категории: проекты, приносящие высокий доход инвесторам за счет генерируемого будущего свободного денежного потока и социально-значимые проекты, не генерирующие непосредственно достаточного денежного потока, но создающие необходимые условия для формирования высокого уровня инвестиционного климата и деловой среды. Определение критериальной группы инвестиционного проектов позволяет в дальнейшем сформировать портфель, определяющий стратегическое развитие региона в области инвестиционных решений.

The development and consistent implementation of the region's investment strategy is the basis of macroeconomic stability and magnification of investment attractiveness. In this article, the authors have proposed an algorithm for forming a region's investment projects portfolio by ranking them into two categories. Projects that bring high income to investors due to the generated future free cash flow and socially significant projects that do not directly generate sufficient cash flow but create the necessary conditions for forming a high level of investment climate and business environment. The definition of the criterion group of investment projects makes it possible to develop further a portfolio that determines the region's strategic development in the field of investment decisions.
Integration of the regional economies of the people's Republic of China and the Russian Federation under the imperatives of accelerating the global energy transition
Authors: Филобокова Л.Ю.
Published: March 2022

Ускорение мирового энергетического перехода обусловлено императивами обеспечения устойчивого социально-экономического развития, в условиях которого экологическая детерминанта приобретает особое значение и ставит на повестку получение синергетического эффекта от взаимодействия энергетической эффективности, децентрализации, диджитализации и декарбонизации. Решение таких задач предстоит обеспечить, прежде всего, на региональном уровне, в том числе и за счет интегрирования экономик КНР и РФ. Выдвигается и защищается положение о том, что двусторонняя интеграция региональных экономик КНР и РФ, в условиях ускоренного энергетического перехода, сопровождаемого повышенными рисками и высокой степенью неопределенности, способна обеспечить странам приток экономических выгод, решение ряда экологических и социальных проблем.

The acceleration of the global energy transition is due to the imperatives of ensuring sustainable socio-economic development, in which the environmental determinant is of particular importance and puts on the agenda the receipt of a synergistic effect from the interaction of energy efficiency, decentralization, digitalization and decarbonization. The solution of such tasks will have to be provided, first of all, at the regional level, including through the integration of the economies of the PRC and the Russian Federation. The position is put forward and defended that the bilateral integration of the regional economies of the PRC and the Russian Federation, in the conditions of an accelerated energy transition, accompanied by increased risks and a high degree of uncertainty, can provide countries with an influx of economic benefits, solving a number of environmental and social problems.
Assessment of innovative activities of small enterprises when deciding on the allocation of state support in the digital economy
Authors: Зайцев И.А.
Published: March 2022

В статье рассмотрены рекомендации Правительства и правительственных структур по переходу малых предприятий народного хозяйства России к цифровой экономике. Продемонстрирована необходимость выделять государственную поддержку для обеспечения успешного перехода предприятий к работе с использований современных цифровых технологий, а также с применением отвечающих современным требованиям организационным практикам и управленческим методам. В статье рассмотрена методика оценки инновационной деятельности малого предприятия, результаты оценки по которой учитываются при принятии решения о выделении государственной финансовой поддержки.

The article discusses the recommendations of the Government and government agencies on the transition of small enterprises of the national economy of Russia to the digital economy. The need to allocate government support to ensure a successful transition of enterprises to work using modern digital technologies, as well as using organizational practices and management methods that meet modern requirements, is demonstrated. The article discusses the methodology for assessing the innovative activity of a small enterprise, the results of which are taken into account when deciding on the allocation of state financial support.
Methodological support for assessment of the spatial potential of urban agglomerations import substitution
Authors: Мачин К.А.
Published: March 2022

Стагнация процессов глобализации в современной агломерационной экономике России позволяет искать новые стратегии развития региональных экономических систем. Процессы импортозамещения способствуют поиску потенциальных направлений развития торгово-производственной сферы агломераций. Оценка потенциала импортозамещения агломерации может осуществляться на основе эконометрического моделирования структуры импорта региональной территориальной экономической системы с выделением индивидуальных фиксированных эффектов потенциальных импортозамещающих товаров. Индивидуальные эффекты, характеризующие особенности спроса и потребления конкретного товара, позволяют оценить степень потребности в нем. Методический комплекс предлагаемый авторами работы позволяет провести количественную и номенклатурную оценку потенциала импортозамещения вплоть до четырехзначной номенклатуры ТН ВЭД.

The stagnation of globalization processes in the modern agglomeration economy of Russia makes it possible to search for new strategies to develop regional economic systems. Import substitution processes contribute to the search for potential directions for the development of the trade and production sphere of agglomerations. The assessment of the agglomeration potential for import substitution can be carried out on the basis of econometric modeling of the import structure of the regional territorial economic system with the allocation of individual fixed effects of potential import-substituting goods. Individual effects characterizing the features of demand and consumption of a particular product allow us to assess the degree of need for it. The methodological complex proposed by the authors of the work allows to make a quantitative and nomenclative assessment of the import substitution potential up to a four-digit nomenclature of Customs Commodity Code
Analysis of uncertainty and error of results in measurement of physical and mechanical parameters of materials
Authors: Фролов С.В.
Published: March 2022

В статье изложен анализ оценки результатов измерений физико-механических параметров металлопродукции (прямые однократные измерения твердости и косвенные однократные измерения предела прочности) на основе расчетов границ погрешности и расширенной неопределенности в соответствии с требованиями национальных и международных стандартов. Приведены количественные расчеты степени увеличения границ расширенной неопределенности результата косвенных измерений предела прочности при учете коэффициентов чувствительности, что важно при оценке соответствия продукции установленным требованиям.

The article presents the analysis of the measurement results of physical and mechanical parameters of metal products (direct single hardness measurements and indirect single strength measurements) based on calculations of error limits and extended uncertainty in accordance with the requirements of national and international standards. Quantitative calculations of the extent of increased limits of extended uncertainty of the result of indirect measurements of ultimate strength are given taking into account sensitivity factors, which is important when assessing product compliance with established requirements.
Multiple sun-synchronous orbits for full coverage of the Earth
Authors: Виноградов Д.Ю.
Published: March 2022

В данной статье произведена систематизация и развитие материалов, изложенных в [1], по проектированию кратных солнечно-синхронных орбит полного покрытия Земли. Разработан алгоритм формирования каталога орбитальных структур космической системы в первом приближении на кратных околокруговых солнечно-синхронных орбитах. Приведён фрагмент каталога орбит для конкретных исходных данных в качестве примера.

In this article the systematization and development of the materials described in [1] on the design of multiple sun-synchronous orbits of the full coverage of the Earth is carried out. An algorithm for forming a catalog of satellite constellation in the first approximation on multiple near-circular sun-synchronous orbits is developed. A fragment of the orbit catalog for specific source data is given as an example.
The accuracy of measuring the information parameter of the signal by a tracking meter in aviation and rocket and space technology against the background of additive and multiplicative interference. Measurement of arrival time. Part III
Authors: Артюшенко В.М. , Воловач В.И.
Published: March 2022

Рассмотрено и проанализировано влияние мультипликативных помех, действующих одновременного с аддитивными помехами, на точность измерения времени прихода информационного сигнала следящим измерителем. Проанализированы зависимости отношения дисперсии измерения времени прихода при наличии мультипликативных и аддитивных помех к дисперсии измерения времени прихода при наличии только аддитивных помех.

The influence of multiplicative interference acting simultaneously with additive interference on the accuracy of measuring the time of arrival of the information signal by the tracking meter is considered and analyzed. The dependences of the ratio of the variance of the arrival time measurement in the presence of multiplicative and additive interference to the variance of the arrival time measurement in the presence of only additive interference are analyzed.
Statistical Control of the Reliability of Rocket and Space Technology Systems with a Consistent Structure at the Stage of Ground Testing
Authors: Рудаков В.Б.
Published: March 2022

Рассматривается статистический контроль надежности сложных систем ракетно-космической техники (РКТ), состоящих из независимых последовательно соединенных компонент. При этом для компонент и системы в целом проводится контроль совокупностей заданных значений их технических параметров, предшествующий контролю заданного значения показателя надежности системы в целом. Впервые получены математические зависимости для определения достоверности контроля надежности систем с последовательной структурой, которые учитывают результаты предшествующего структурно-иерархического контроля их технических параметров. Практическое использование этих зависимостей приводит к повышению достоверности контроля заданных требований к надежности систем с последовательной структурой, снижению рисков принятия ошибочных решений и сокращению экономических затрат на наземную отработку.

In the article it is considered the statistical control of reliability of complex systems of rocket and space technology (RST) consisting of independent sequentially connected components. At the same time, it is carried out the control of the sets of set values of the technical parameters for the components and the system as a whole preceding the control of the set value of the reliability indicator of the system. For the first time, mathematical dependences were obtained to determine the reliability of reliability control of systems with a sequential structure, which take into account the results of the previous structural and hierarchical control of their technical parameters. The practical use of these dependencies leads to an increase in the reliability of the control of the specified requirements for the reliability of systems with a consistent structure, reducing the risks of making erroneous decisions and reducing the economic costs of ground testing.
Application of clustering and machine learning for building of a recommendation system for determining of scientific articles relevance
Authors: Мосалов О.П. , Иванов И.А. , Першин М.А.
Published: March 2022

В статье представлено решение задачи построения рекомендательной системы для определения актуальности научных публикаций. Рассматривается алгоритм определения актуальностей, а также применяемые методы машинного обучения для обработки текстовой информации. Рассмотрено и обосновано применение векторных представлений слов и кластеризации.

In the article a solution of a task of developing a recommendation system for determining of scientific article relevance is presented. An algorithm for calculation of relevance and applied methods of machine learning for text data processing are considered. Usage of word embeddings and clustering are justified.
KRİZLER ÇAĞINDA YOKSULLUK: SOSYAL TRANSFERLERİN ÖNEMİ ve ETKİNLİĞİ
Authors: ASLAN Gürdal
Published: March 2022

Küresel ve ulusal ölçekte, mevcut sosyoekonomik sorunları derinleştiren ve tekrarlayan ekonomik-finansal, sosyal krizler ve sağlık krizleri çağında yaşamaktayız. Diğer küresel kriz süreçlerinde gözlemlediği gibi Covid-19 salgınının neden olduğu ekonomik durgunluk, gelir kaybı ve istihdam krizi neticesinde de yoksulluğun önemli oranda arttığı belirtilmektedir. Ayrıca, yapılan araştırmalarda artan yoksulluğa karşı kapsayıcı ve etkili sosyal transferlere olan ihtiyaca dikkat çekilmektedir. Bu durum, sosyal transferlerin dinamiklerinin ve etkinliğinin sorgulanmasını gerektirmektedir. Mevcut çalışma Türkiye’de sosyal transferlerin etkinliğini ve yoksulluk üzerine olan etkisini Gelir ve Yaşam Koşulları Anketleri verilerini kullanarak araştırmaktadır. Çalışmanın bulguları sosyal transferlerin yoksulluğu azaltıcı etkisinin 2006-2018 yılları arasında yüzde 6’dan yüzde 19’a yükseldiğini ortaya çıkarmaktadır. Bu belirgin iyileşmeye rağmen AB-28 ülkelerine kıyasla Türkiye’de sosyal transferlerin görece ve yeterince etkin olmadığı tespit edilmiştir. Tüm sosyal transferlerin yüzde 91’ini oluşturan prime dayalı emeklilik, dul-yetim aylıklarına yoksulların sadece yüzde 7’si ulaşabilmektedir. Bu duruma yoksullar arasında istihdam oranının düşük ve kayıt dışı çalışmanın yaygın olması neden olmaktadır. Uzun vadede işgücüne katılımı ve istihdamı artıracak, kayıt dışılığı azaltacak politikalar yoksulluğu azaltacaktır. Fakat krizler sonucu artması beklenen yoksulluğa karşı kısa vadede ve ivedilikle cevap verebilmek için primsiz sistemdeki transferlerin (ayni ve nakdi sosyal yardımlar, konut, çocuk yardımları gibi) kapsamını artıracak politikalar uygulanmalıdır. Nitekim yoksulların sosyal transferlere erişimi arttıkça yoksulluk oranın azaldığı tespit edilmiştir.
Travma Bilgili Bakım ve Sosyal Hizmet
Authors: GUNES ASLAN Guler
Published: March 2022

Travma, bireylerin yaşamlarını ve fiziksel bütünlüklerini tehdit eden çeşitli olumsuz olaylar sonucunda ortaya çıkmaktadır. Travma bireylerin sağlığı ve kişiler arası ilişkileri üzerinde kısa ve uzun vadede olumsuz etkiler yapabilmektedir. Travmanın insan yaşamı üzerinde olumsuz sonuçlara neden olması, travmatik yaşam öyküsü olan bireylere yönelik uygulama yaklaşımları geliştirilmesi konusunu da gündeme getirmiştir. Bunun için alanyazında travma bilgili bakım konusu gündeme gelmiştir. Travma bilgili bakım, travmanın yaygınlığının ve etkilerinin farkında olunması ve travma öyküsü olan bireylere yönelik uygulamaların ve kurumsal düzenlemelerin buna göre şekillendirilmesi üzerine inşa edilmiştir. Travma bilgili bakım, travma öyküsü olan birey ve topluluklar hakkında çalışmalar yapılan sosyal hizmet bilimi ve uygulaması için yol gösterici olabilecek bir yaklaşımdır.

Bu çalışmada Amerika Birleşik Devletleri’nde bulunan Madde Bağımlılığı ve Ruh Sağlığı Hizmetleri İdaresi (SAMHSA) isimli kurum tarafından travma bilgili bakımla ilgili ortaya konan varsayım, temel ilke ve uygulama alanlarına yer verilmiş ve sosyal hizmet alanına uyarlanmasına çalışılmıştır. Türkiye’deki alanyazında sosyal hizmet ve travma konusuna yeterince yer verilmediği için, çalışma alanyazına katkı sağlayacaktır
Design and noise-reduction simulation of an acoustic metamaterial plate incorporating tunable shape memory cantilever absorbers
Authors: Xu Teng , Wu Yi-Ting , Lee Chun-Ying
Published: March 2022

Metamaterials are materials having artificially tailored internal structure and unusual physical and mechanical properties. Due to their unique characteristics, metamaterials possess great potential in engineering applications. This study proposes a tunable metamaterial for the applications in acoustic isolation. Therefore, a stopband in the dispersion curve can be created because of the energy gap. For the conventional metamaterial, the stopband is fixed. Although the metamaterial with tunable characteristics has been proposed in the literature to extend its working stopband, the efficacy is usually compromised. In this study, cantilevers of tunable shape memory materials (SMM) via controlled phase transformation are incorporated into the metamaterial plate. Its theoretical finite element formulation for determining the dynamic characteristics is established. The effect of the configuration of the SMM cantilever absorbers on the metamaterial plate for the desired stopband in wave propagation is simulated by using finite element model and a commercial multi-physics software. The result demonstrates the tunable capability on the stopband of the metamaterial plate under different activation controls of the SMM absorbers, and shows the ability to trap the vibration at the designed frequency and prevent vibration wave from propagating downstream in different absorber arrangements and alloy phases. It should be beneficial to precision machinery and defense industries which have desperate need in vibration and noise isolation.
Leakage detection in water distribution networks using space search reduction and local fitness in steady-state and EPS (case study: water distribution network of Birjand)
Authors: Nasirian Ali , Ahrari Marzieh
Published: March 2022

Using hydraulic model calibration of a water distribution network is one of the methods that can reduce leak detection costs by identifying areas with high leakage. In the present paper, a new factor called local fitness is used in combination with the search space reduction method to obtain an optimal answer. In this method, a fitness function is calculated for each zone. For each zone, proximity of the pressure and flow rates obtained from the model to the corresponding observational data indicates that the values selected for the nodes of that zone are close to the correct values. In the next steps, using a search space reduction method and performing the optimization process with the local fitness function, the chance of selecting those values is increased. In this study, leakage was assigned to nodes with emitter coefficient. This method was used on the water distribution network of Birjand. Three factors of background leakage, leakage hotspot and apparent losses were considered as unknown parameters. Results of the present method were compared with the results of a genetic algorithm (GA) and the corresponding exact values. Based the results, the present method showed better results in terms of convergence speed and accuracy.