bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of mental, neurological and substance use conditions and case detection at primary healthcare facilities across three districts in Ghana: findings from a cross-sectional health facility survey
Authors: Ae-Ngibise Kenneth A. , Sakyi Lionel , Adwan-Kamara Lyla , Lund Crick , Weobong Benedict
Published: October 2022

Background: Few studies have examined the prevalence of mental, neurological and substance use disorders, case detection and treatment in primary healthcare in rural settings in Africa. We assessed needs and case detection rate at primary healthcare facilities in low-resource settings in Ghana.
Methods: A cross-sectional study was conducted at the health facility level in three demonstration districts situated in Northern, Middle and Southern belts in Ghana. These districts are Bongo (Upper East Region), Asunafo North (Ahafo Region) and Anloga (Volta Region). Data were collected on five priority mental, neurological and substance use conditions of interest including depression, psychosis, suicidal ideation, epilepsy and alcohol use disorders.
Results: Nine hundred and nine (909) people participated in the survey. The prevalence of depression was 15.6% (142/909), psychosis was 12% (109/909), suicidal ideation was 11.8% (107/909), epilepsy was 13.1% (119/909) and alcohol use disorders was 7.8% (71/909). The proportion of missed detection for cases of depression, psychosis, epilepsy and alcohol use disorders (AUD) ranged from 94.4% to 99.2%, and was similar across study districts. Depression was associated with psychosis (RR: 1.68; 95% CI: 1.12-1.54). For psychosis, a reduced risk was noted for being married (RR: 0.62; 95% CI: 0.39-0.98) and having a tertiary level education (RR: 0.12; 95% CI: 0.02-0.84). Increased risk of suicidal ideation was observed for those attending a health facility in Asunafo (RR: 2.31; 95% CI: 1.27-4.19) and Anloga districts (RR: 3.32; 95% CI: 1.93-5.71). Age group of 35 to 44 years (RR: 0.43; 95% CI: 0.20-0.90) and attending a health facility in the Anloga district (RR: 0.43; 95% CI: 0.20-0.90) were associated with reduced risk of epilepsy, but not for those more than 35 years (RR: 3.06; 95% CI:1.14-8.24). Being female (RR: 0.19; 95% CI: 0.12-0.31) and having a tertiary education were associated with reduced risk of AUD (RR: 0.27; 95% CI: 0.08-0.92).
Conclusions: Our study found a relatively high prevalence of MNS conditions, and very low detection and treatment rates in rural primary care settings in Ghana. There is a need to improve the capacity of primary care health workers to detect and manage mental health conditions, together with improved medication supply and referral pathways.
The satellite monitoring of eutrophication processes in a section of the transboundary Argun (Hailar) River using the surface algal bloom index (SABI) according to Landsat remote sensing data
Authors:   Transbaikal State University, Chita, Kurganovich К.
Published: October 2022

The article is devoted to the monitoring of eutrophication processes in the transboundary section of the Argun River according to Landsat 8 OLI remote sensing data. To assess the impact of intense algal blooms in the water of the Argun River, a 956 km long section from the city of Khailar (China) to the village of Argunsk (Russia) was selected for the time period from May to October 2020, corresponding to the growing season. Based on the analysis of spatio-temporal changes in the surface algal bloom index (SABI), the main areas of eutrophication and time intervals of the greatest deterioration in the quality of the waters of the Argun River were identified. The maximum values of the SABI index indicate the development of algae near the water surface, and low or negative values are an indicator of the development of algae in the deeper layers of the water column, or their absence. It is noted that the SABI index is best suited for assessing the intensity of blooming of river water, which does not have a significant depth, in cases of predominantly superficial concentration of algae. In order to separate the mask of the water surface of the river to ensure the extraction of the SABI index only from the pixels related to the water body, the spectral water index MNDWI was used, the positive values of which indicate belonging to the water surface. To assess the possible sources of algae biomass entry into river waters, a comparative analysis of SABI changes in the system of floodplain lakes along the Argun River – Khara-Nur, Burgat-Nur, Khuretuy, Bara-Nur, Pandza-Nur, Khorubo-Nur, Hulun Lake located in China, was carried out
On the political and social aspects of the transformations of Peter the Great in the context of the world historical process
Authors:   National Research Moscow State University of Civil Engineering, Mezentsev S.
Published: October 2022

The subject of this article is the political and social reforms of Peter the Great, considered in the context of the world-historical process. The subject of the study is the political and social reforms carried out by Peter the Great, which, on the one hand, accelerated, and on the other hand, hampered the modernization of Russia, its formation as a European and world power. The purpose of the study is to identify and determine the links between Peter the Great's political and social transformations and the logic of the world-historical process. The theoretical and methodological basis of scientific and philosophical research are the concepts of socio-economic formations of K. Marx, the stages of economic growth of W. W. Rostow, the post-industrial society of D. Bell and the «third wave» of E. Toffler. The absolutist state built during Peter the Great's transformations and the establishment of an unlimited monarchy corresponded to the development of the last stage of feudalism in Russia, which flourished in a number of Western European countries in the XVII-XVIII centuries. The streamlining of the structure of public administration is quite consistent with the rationalization of the bureaucratic apparatus in the Western European countries of that time. The formation of the nobility as a class, the growth of the merchant class, the division of urban residents into regular and irregular, the emergence of industrialists and «possessional peasants», the strengthening of serfdom, the emergence of a social stratum consisting of knowledge workers, although contradictory, but generally fit into the hierarchical structure of European late feudal society and the beginning of Modern times. As a result, the modernization carried out by Peter the Great brought Russia into the circle of leading European powers, brought it from the sidelines onto the road of the world historical process. It was thanks to the political and social experience, borrowed in many respects from the leading European powers, that Russia at that time took a worthy place on the world stage. Peter's transformations and their results remain relevant to this day and can be in demand again
Molecular Diversity of Microbes Associated with Fermented Bamboo Shoots
Authors:   Himalayan School of Biosciences, Swami Rama Himalayan University, Swami Rama Nagar, Jolly Grant, Dehradun, Uttarakhand 248140 India, Kumar Vijay , Naik Bindu ,   Department of Life Sciences, Food Technology, Graphic Era (Deemed to be University), Bell Road, Clement Town, Dehradun, Uttarakhand 248002 India, Sharma Sachin ,   Department of Food Technology, Doon (P.G.) College of Agriculture Science and Technology, Selaqui, Dehradun, Uttarakhand 248011 India, Kumar Akhilesh ,   Himalayan School of Biosciences, Swami Rama Himalayan University, Swami Rama Nagar, Jolly Grant, Dehradun, Uttarakhand 248140 India, Khan Javed Masood ,   Department of Food Science and Nutrition, Faculty of Food and Agricultural Sciences, King Saud University, 2460, Riyadh 11451, Saudi Arabia, Irfan Mohammad ,   Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA
Published: October 2022

Fermented bamboo shoots are rich in high protein, carbohydrates, fibre and minerals while low in fat content. In the North-East region of India and other Asian countries, they are mostly used in various food preparations. The present study was undertaken to explore the diversity of bacteria associated with Bamboo shoots and to evaluate their antibacterial profile. Based on the results the fermented bamboo shoots showed viable counts ranging from 6.55 ± 0.91 log CFU/g to 7.86 ± 1.21 log CFU/g. The 16s rRNA sequence analysis showed that these isolates belonged to the genus Bacillus (Bacillus safensis, B. tequilensis, B. siamensis, B. nakamurai, B. subtilis) and Enterobacter. These isolates have not been reported previously from fermented bamboo shoots except B. subtilis. Surprisingly, no Lactobacillus species or molds were found in any of the samples tested. Potent antibacterial activity was recorded against Klebsiella, Staphylococcus aureus, Salmonella and B. cereus.
Syringe labelling in anaesthesia and critical care areas: review 2022
Authors:   Equipment Standards Committee Association of Anaesthetists, Boaden Dr Bill
Published: October 2022

This document replaces the Association of Anaesthetists’ previous guidance1 on this topic, following the publication of BS ISO 26825:2020. BS ISO 26825:2020 is the second edition of the standard for user-applied labels for syringes containing drugs used in anaesthesia. It technically revises, cancels and replaces the 2008 first edition. It gives requirements for labels attached to syringes so that the contents can be identified during anaesthesia and covers the colour, size, design and general properties of the label and the typographical characteristics of the wording for the drug name. Its purpose is solely for use in anaesthesia and as such covers a range of core drug groups. It is acknowledged that these labels may find a use in other critical care areas. The main technical reason for the revision of BS ISO 26825 was to improve the colour, size and design of the labels. Several labels were revised to take account of comments made regarding their clarity and possibility of confusion in use.
Towards Transforming Osogbo into a Sustainable City, The Remote Sensing Perspective
Authors: Aluko Olawale Williams , Okhimamhe Apollonia , Abubaker Sadiq
Published: October 2022

This study has examined the impact of rapid urbanization on the sustainable development of Osogbo and demonstrated the use of remote sensing as a tool in achieving a sustainable city. Having identified urbanization in its entirety as a major determinant of whether or not a city will and can attain sustainability. Primary data through questionnaires administration was employed to obtain data on demography, occupation, waste management practices, etc, and three Landsat images (Landsat TM 5, ETM +7, and Landsat 8 OLI/TIRS) covering Osogbo for the years 1998, 2002 and 2017 respectively were analyzed into different land use land cover classes to demonstrate the impact of rapid urbanization on the study area over space and time serving as the major source of secondary data. The research revealed that, over the years there has been a shift from the vegetative type of land cover to other types of land use particular among which are settlement and commercial land use types leading to a considerable increase in urban area and a decrease in vegetation as evident in the analyzed satellite images and the questionnaire report. Based on the questionnaire report and field survey, there seems to be some positive change in Osogbo, especially in terms of waste management, road networks, and education facilities, which can be attributed to the state government’s effort in making the capital city more conducive for residents and befitting as a state capital, but the city can still not be considered as been on the path to sustainability. Being the administrative and commercial center of Osun state, the city keeps increasing in population and as agreed by the respondents, there is the danger of overcrowding, destruction of green areas to erect buildings, increasing rate of unemployment, deforestation, and other population-related issues. These don’t in any way portray Osogbo as a sustainable city or one in the making. Also, the city’s energy sector is still highly dependent on fossil fuels (petroleum), and the transportation system needs improvement to reduce the city’s contribution to the greenhouse gas effect.
The fiction of scarcity : conceptualising scarcity in terms of global justice
Authors:   , Brotherton Michelle
Published: October 2022

This thesis intends to contribute to the discourse on global justice as it pertains to resources, the distribution of resources, and the allocation of resources. The focus is on the concept of scarcity. I examine scarcity for how it is understood, interpreted, and applied in the literature on global justice. This thesis argues that scarcity lacks conceptual clarity in the discourse on global justice and argues that if scarcity is misconstrued, the consequences can be severe. Conceptual clarity is thus necessary to ensure that scarcity is properly referred to in the discourse on global justice so that scarcity is not erroneously used when justifications are sought for material deprivation and consequent human suffering. In the process, I will also examine how scarcity is used as a justification in instances of material deprivation and why this is problematic. Given the lack of conceptual clarity regarding scarcity, I argue that reliance on scarcity as justification may be erroneous. The conflation of absolute scarcity and relative scarcity may amount to a category mistake. This thesis purports to clarify scarcity conceptually in the context of global justice. In doing so, I recommend that a resource-centric approach to resource scarcity is adopted to accurately account for the scarcity status of resources. A resource-centric approach to resource scarcity based on a more nuanced understanding of scarcity avoids the potential category mistake. Such an approach ensures that material deprivation and consequent human suffering are not wrongfully attributed to scarcity.
Cost of capital and firm value: Evidence from Indonesia
Authors: Kurniasih Augustina , Rustam Muhamad , Heliantono  , Endri Endri
Published: October 2022

Cost and capital structure are needed to evaluate the feasibility of the investments made by a company. This study aims to estimate and analyze the effect of the component of cost of capital (COC) and capital structure (CS) on firm value. Pulp & Paper companies listed on the Indonesia Stock Exchange (IDX) became the research sample for the 2013–2020 period. The research method applied is a moderation regression analysis approach. The empirical findings of the study prove that firm value is not influenced by the cost of debt (COD), while the cost of equity (COE) has a negative effect, and COC is positive. COC is a combination of the use of debt and equity, modeling by adding a CS variable as a moderating variable; this leads to the conclusion that COD and COE have a negative effect on firm value, whereas COC and CS have a positive effect. The finding of the role of CS as a moderating variable reveals that CS is a quasi-moderator variable and plays a role in increasing.
PENGEMBANGAN USAHA KECIL MENENGAH MELALUI PENGOLAHAN “BILQIS” DI DESA CIPANAS, JAWA BARAT
Authors:   School of Business and Economics Universitas Prasetiya Mulya, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Ardyanisa Candrika Edith , Serona Ellisa ,   School of Business and Economics Universitas Prasetiya Mulya, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Giovanni Filbert ,   School of Business and Economics Universitas Prasetiya Mulya, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Gunawan Nicholas ,   School of Business and Economics Universitas Prasetiya Mulya, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Raina Mukti Riandra ,   School of Business and Economics Universitas Prasetiya Mulya, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339, Gunawan Vania Pradipta ,   School of Business and Economics Universitas Prasetiya Mulya, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama No.1, BSD City, Kec. Pagedangan, Kabupaten Tangerang, Banten 15339
Published: October 2022

Kecamatan Cipanas, Jawa Barat merupakan sebuah desa berkembang yang memiliki berbagai usaha kecil yang bersaing dalam pasar yang sama, salah satunya adalah usaha Bilqis yang menawarkan makanan ringan tradisional. Sebelum program kemitraan masyarakat ini, usaha tersebut mengalami berbagai permasalahan yang menghambat pertumbuhan, diantara lainnya, keterbatasan modal, inkonsistensi pada kualitas produk, minimnya jalur pemasaran produk, dan ketidakpastian dalam perhitungan biaya modal. Selama kegiatan program kemitraan tersebut, banyak sekali perkembangan yang tercapai untuk memenuhi target jangka pendek, maupun panjang, dan jurnal ini bertujuan untuk menjelaskan serangkaian kegiatan yang dilaksanakan untuk meningkatkan performa bisnis usaha Bilqis. Untuk mendorong perkembangan dan pertumbuhan, sejumlah solusi telah diimplementasikan pada keempat fungsi bisnis, seperti pemasaran, melalui memperkuat identitas merek dengan meningkatkan desain logo dan kemasan produk, membuat alat promosi seperti spanduk dan x-banner untuk meningkatkan kesadaran konsumen terhadap merek, meluaskan sarana distribusi melalui platform daring dan luring, dan diversifikasi produk. Selebihnya, perkembangan pada fungsi operasional merupakan pembuatan system of procedures (SOP) untuk memastikan konsistensi kualitas produk, pada aspek keuangan adalah mengajarkan akuntansi dasar, dan juga pengelolaan sumber daya manusia.
Faktor-Faktor yang Mempengaruhi Continuance Intention dari Pengguna Pada Layanan M-Payment (Studi Kasus Go-Pay)
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Venny Setyadi Elizabeth , Suarly Russel ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Handoko Rudy ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Ali Alavi ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339
Published: October 2022

Pertumbuhan inklusi finansial di Indonesia tidak terlepas dari meningkatnya jumlah pengguna Fintech, khususnya m-payment. Nilai transaksi m-payment di Indonesia terus meningkat seiring waktu. Akan tetapi, nilai pertumbuhannya diperkirakan terus menurun. Kemunculan m-payment dapat memberikan keuntungan bagi pengguna, akan tetapi ada risiko yang tidak bisa dihindari. Meskipun demikian, belum ada penelitian yang membahas benefit-risk framework untuk mobile point-of-sales payment di Indonesia. Model yang diajukan dalam studi ini berdasarkan teori dan penelitian terdahulu dari benefit-risk framework (Ryu, 2018), model formatif yang didasari oleh Net Valence Framework (Kim et al., 2009; Peter dan Tarpey, 1975), yang konsisten didasari oleh Theory Reasoned Action (TRA) (Ajzen dan Fishbein, 1977). Model ini memaparkan faktor-faktor spesifik yang mempengaruhi persepsi pengguna. Persepsi tersebut mempengaruhi continuance intention. Continuance intention merupakan intensi seseorang untuk melakukan pembelian kembali setelah pembelian yang dilakukan sebelumnya. Penelitian ini dilakukan secara kuantitatif dan dianalisis menggunakan AMOS 24.0. Studi ini menemukan bahwa convenience adalah faktor paling dominan mempengaruhi continuance intention secara positif. Sementara itu security risk dominan secara negatif. Secara keseluruhan, ada pengaruh yang signifikan antara perceived benefit maupun perceived risk pada intensi penggunaan selanjutnya. Dalam hal ini, pengguna masih berintensi melanjutkan penggunaan MPP Go-Pay meskipun masih ada faktor risiko yang dirasakan. Penelitian ini dapat menjadi patokan strategi pemasaran perusahaan m-payment seperti contohnya Go-Pay, untuk menyesuaikan persepsi nilai layanan yang ingin ditawarkan perusahaan.
Pengaruh Emosi Wisatawan terhadap Citra Kognitif dan Afektif dalam Wisata Yoga di Bali
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Wahyu Utami Nabilah , Sherviana Sheila ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Istijanto Istijanto ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Yudianto B.Realino ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339
Published: October 2022

Penelitian ini bertujuan untuk menganalisis pengaruh pengalaman emosi wisatawan terhadap niat perilaku melalui citra destinasi dalam melakukan wisata yoga. Namun, ada kesenjangan dalam literatur yang ada saat ini dimana hanya menggunakan satu jenis emosi negatif. Penelitian ini menambahkan emosi negatif; anger dengan tujuan untuk melengkapi literatur dalam memahami pengaruh pengalaman emosi wisatawan terhadap niat perilaku melalui citra destinasi. Penelitian ini dilakukan dengan metode kuantitatif dengan menyebarkan kuesioner online kepada responden yang sudah pernah mengunjungi wisata yoga di area Ubud, Bali. Data dikumpulkan dengan menggunakan metode non-probability sampling dengan teknik snowball dan data yang terkumpul akan dianalisis menggunakan confirmatory factor analysis dan structural equation modeling. Temuan pada penelitian ini mengungkapkan bahwa wisatawan domestik memiliki pengalaman emosional negatif yang memiliki dampak langsung pada citra destinasi dan efek tidak langsung pada niat perilaku. Penelitian ini berupaya untuk memberikan wawasan tentang pengalaman emosional wisatawan yang dapat dipertimbangkan untuk kegiatan pemasaran yang dilakukan oleh bisnis pariwisata yoga, selain itu juga dapat memaksimalkan hal-hal yang mempengaruhi emosi wisatawan seperti fasilitas. Hal ini juga akan membantu pengembangan sektor pariwisata yoga di Ubud, Bali.
Perbandingan Penggunaan Branded Emoticon yang Mengandung Kelucuan di Dua Negara
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Calista Calista , Soetijoso Winnie Wiwa ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Ratna Tercia Christiana Yosevina ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Sumarlin Antonius W. ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339
Published: October 2022

Saat ini, Mobile Instant Messaging (MIM) telah menjadi fitur yang secara umum digunakan untuk memperkuat hubungan antara konsumen dengan merek. Penggunaan emotikon dalam MIM digunakan sebagai strategi oleh merek-merek terkenal sebagai influencer merek yang berperan untuk menyampaikan pengetahuan merek (brand knowledge) kepada konsumen lainnya, yang dikenal sebagai hubungan antara konsumen ke konsumen (C2C). Melanjutkan studi penelitian sebelumnya mengenai penggunaan branded emoticon dalam meningkatkan strategi C2C terdapat dua karakteristik tipe emotikon, yaitu: Kindchenschema dan Whimsical dalam studi kasus merek Three Squirrel di China. Peneliti mengeksplorasi kemungkinan efektifnya penggunaan branded emoticon tersebut di Indonesia melalui studi kasus terhadap merek Dunkin Donuts di Indonesia. Studi dilakukan melalui aplikasi MIM paling umum di Indonesia: WhatsApp. Riset data diperoleh secara purposive dan disebarkan secara on-line dengan total sampel sebanyak 400 responden yang diproses melalui SPSS 22 dan software AMOS 24 untuk menyesuaikan model persamaan struktural. Pada penelitian ini ditemukan bahwa kelucuan Kindchenschema dan Whimsical dapat memunculkan intensi pembelian dan kelekatan pada aplikasi WhatsApp melalui keseruan dan brand engagement yang tercipta. Ditemukan juga bahwa diantara kedua kelucuan tersebut, kelucuan Whimsical memiliki pengaruh yang lebih besar terhadap munculnya intensi pembelian dan kelekatan pada aplikasi WhatsApp.
Faktor Kredibilitas Ulasan Online dan Pengaruhnya terhadap Citra Merek dalam Konteks Produk Pensil Alis di Sociolla
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339, Erika Anastasia , Olivia Olivia ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339, Murniadi Krishnamurti ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339, Yudianto Bernardinus Realino ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339
Published: October 2022

Sejak Covid-19 dan penerapan kebijakan Pembatasan Sosial Berskala Besar (PSBB) membawa potensi perubahan yang sangat signifikan dalam pola berbelanja konsumen. Hal ini tentunya memicu perubahan pola pembelian dari offline menjadi online melalui platform e-commerce. Perkembangan tren industri kecantikan juga dapat mempengaruhi pola konsumsi masyarakat akan kosmetik. Penelitian ini merupakan replikasi dari studi Chakraborty dan Bhat (2018) mengenai topik kredibilitas ulasan online serta citra merek dari segi fungsional dan hedonis. Namun peneliti melakukan perubahan konteks dari produk elektronik menjadi produk makeup dengan spesifikasi produk pensil alis dalam platform Sociolla. Sehingga peneliti ingin mengembangkan penelitian ini dengan tujuan untuk mengetahui faktor kredibilitas ulasan online dan pengaruhnya terhadap citra merek baik dari segi fungsional dan hedonik dalam konteks produk pensil alis di Sociolla di Jabodetabek. Dengan target sampel kurang lebih 325 responden dan setelah menjalani tahap data cleaning di eliminasi menjadi 302 responden menggunakan teknik sampling purposive dilengkapi dengan teknik aksidental. Kemudian akan diuji tahap lanjut melalui analisis Structural Equation Modeling (SEM). Dari penelitian ini didapat 3 temuan utama: (1) review quality dan review consistency berpengaruh positif terhadap ulasan online yang kredibel, (2) receiver berpengaruh secara parsial terhadap credible online review, dan (3) ulasan online yang kredibel berpengaruh positif terhadap functional brand image. Dari sisi teoritis, penelitian ini berkontribusi dalam bidang literatur pemasaran terkait topik ulasan online yang kredibel dan citra merek pada platform e-commerce. Dari sisi praktis, penelitian ini dapat mengembangkan ulasan online bagi e-commerce yang bermanfaat untuk membantu perusahaan menyusun strategi yang dapat mendorong pelanggan untuk menulis ulasan yang kredibel.
Pengaruh Nilai Konsumsi, Interpersonal Influence dan Kepuasan terhadap Niat Pembelian Barang Virtual dalam Mobile Games
Authors:   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339, Hendrata Giovanni Putri , Wan Peter ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339, Prasetya Prita ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339, Budiman Arief ,   Sekolah Bisnis dan Ekonomi, Universitas Prasetiya Mulya, Kampus BSD, BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan,Tangerang, Banten 15339
Published: October 2022

Pertumbuhan industri game kian berkembang setiap tahunnya, kini para pengembang game kini terus berinovasi untuk membuat berbagai fitur dan barang kosmetik yang dapat dibeli dan dinikmati oleh seluruh pemainnya. Meskipun adanya potensi pertumbuhan yang besar akan pembelian barang-barang di dalam mobile games, sedikit yang diketahui tentang apa yang memotivasi para pemain mobile games untuk melakukan pembelian barang di dalam game tersebut. Tujuan dari penelitian ini adalah untuk mencari tahu apa saja faktor yang berpengaruh terhadap niat pembelian barang virtual di permainan seluler Mobile Legends: Bang Bang di Indonesia. Analisis SEM (Structural Equation Model) dengan aplikasi AMOS dilakukan pada 285 data sampel yang diperoleh dari kuesioner online dengan teknik judgemental dan snowball sampling. Penelitian ini menunjukkan tiga temuan utama: (1) enjoyment value, monetary value dan kepuasan terbukti secara signifikan mendorong continuous usage intention, (2) enjoyment value, social value, monetary value, interpersonal influence dan continuous usage intention berpengaruh positif terhadap niat pembelian barang virtual. Secara teoritis, temuan penelitian ini mendukung temuan terdahulu bahwa 3 aspek pada teori nilai konsumsi dan interpersonal influence memiliki hubungan yang positif terhadap niat pembelian barang virtual, serta memberikan perspektif baru terhadap teori kepuasan dan continuous usage intention pada konteks ini. Secara praktis, baik publisher maupun developer mobile games dapat meningkatkan kualitas daya tarik barang virtual yang dimilikinya dan meningkatkan pengaruh interpersonal influence sebagai teknik untuk meningkatkan continuous usage intention dan keinginan para pemain untuk membeli barang virtual.
Faktor Faktor yang Mempengaruhi Pembelian Impulsif Konsumen pada M-Commerce
Authors:   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Gunawan Natasya , Limantoro Shania Devina ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Istijanto Istijanto ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Handoko Rudy ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Rustandi Fredy Utama ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia.
Published: October 2022

M-commerce muncul berkat pesatnya perkembangan teknologi sebagai alternatif dalam melakukan bisnis. Kini m-commerce semakin berkembang dan menjadi fenomena di media sosial di Indonesia. Salah satu fenomena menarik adalah perilaku impulsif konsumen dalam m-commerce, yang telah dibuktikan meningkat oleh beberapa penelitian terdahulu. Meskipun demikian, studi terkait faktor pembelian impulsif dan pengaruhnya dalam m-commerce masih terbatas, khususnya di Indonesia. Berdasarkan stimulus-organism-response (S-O-R), penelitian ini berfokus pada faktor situasional yaitu pengaruh interpersonal (interpersonal influence), daya tarik visual (visual appeal), portabilitas (portability), variasi pilihan (variety of selection), dan atribut harga (price attribute) dalam m-commerce untuk meneliti pembelian impulsif. Mengikuti literatur sebelumnya tentang penelusuran dan teori motivasi, studi ini bertujuan untuk meneliti penelusuran hedonik dan utilitarian sebagai dua pendorong utama pembelian impulsif konsumen dalam m-commerce. Studi ini mengadopsi estimasi partial least squares untuk menganalisis data yang diperoleh dari kuesioner online dengan teknik judgemental dan snowball sampling. Tiga temuan utama dalam penelitian ini: yang pertama, daya tarik visual, variasi pilihan dan atribut harga pengaruh interpersonal dan daya tarik visual berpengaruh positif terhadap penelusuran hedonik dan utilitarian namun portabilitas tidak berpengaruh terhadap keduanya, kedua pengaruh interpersonal berpengaruh positif terhadap penelusuran utilitarian, dan ketiga penelusuran hedonik dan utilitarian berpengaruh positif terhadap pembelian impulsif. Secara teoritis, temuan penelitian ini memberikan perspektif baru terhadap teori motivasi konsumen online dengan melihat penelusuran hedonik dan utilitarian sebagai dua motivasi yang berbeda. Secara praktis, perusahaan m-commerce di Indonesia dapat meningkatkan kualitas faktor-faktor situasional untuk meningkatkan kecenderungan pembelian impulsif konsumen.
Pengaruh Stimulus dalam Pembentukan Perceived Value, Trust, dan Loyalty Intention pada Social Commerce Soco By Sociolla
Authors:   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Andriputra Justin Ariel , Raina Mukti Riandra ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Yosevina Christiana ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia., Sirad Dini Anggraeni ,   Universitas Prasetiya Mulya BSD City Kavling Edutown I.1, Jl. BSD Raya Utama, BSD City, Kec. Pagedangan, Tangerang, Banten 15339, Indonesia.
Published: October 2022

Social commerce merupakan fenomena bisnis yang muncul dari penggunaan media sosial untuk transaksi e- commerce, yang sedang bertumbuh secara pesat di Indonesia. Penelitian ini adalah adaptasi dan modifikasi dari penelitian sebelumnya di mana aspek social commerce website design seperti Information Quality, Service Quality, Rewards and Recognition, dan Customization mempengaruhi intensi loyalitas konsumen. Perbedaan dalam penelitian ini adalah penambahan variabel Trust dan konteks lokasi penelitian yaitu di Indonesia, serta brand social commerce, yaitu SOCO by Sociolla. Tujuan riset ini adalah untuk meneliti apakah aspek social commerce website design dapat mempengaruhi Perceived Value dan Trust, yang lalu dapat membentuk intensi loyalitas konsumen, melalui konsep Stimulus-Organism-Response (S-O-R). Metode sampling yang digunakan adalah non probability, purposive sampling dalam mengumpulkan 382 data sampel melalui kuesioner online. Data diolah menggunakan analisis Structural Equation Modeling dengan AMOS. Hasil menunjukkan bahwa Information Quality dan Service Quality mempengaruhi Perceived Value dan Trust. Customization juga mempengaruhi Perceived Value, namun Rewards and Recognition tidak berpengaruh. Dalam pembentukan Loyalty Behavior Intentions, Perceived Value memiliki pengaruh yang signifikan dan kuat dalam meningkatkan Positive eWOM Intention dan Customer Engagement Behavior Intention, namun Trust tidak dapat mempengaruhi Positive eWOM Intention, dan menunjukkan hubungan negatif terhadap Customer Engagement Behavior Intention. Secara teoritis, temuan penelitian ini berkontribusi kepada literatur mengenai anteseden customer Perceived Value, Trust, dan Behavioral Intentions dalam konteks social commerce. Secara praktis, perusahaan social commerce di Indonesia dapat meningkatkan aspek social commerce website design, dan mengevaluasi Rewards and Recognition yang diimplementasikan untuk meningkatkan Perceived Value yang berdampak kepada loyalty behavior intentions.
Identifying determinants of sustainable water management at the household level through rainwater harvesting systems in Nepal
Authors: Thapa Anusha , Khanal Ghanashyam , Mahapatra Sushanta Kumar , Devkota Niranjan , Mahato Surendra , Paudel Udaya Raj
Published: October 2022

The urban water supply systems around the world are highly stressed at present due to growing water demand caused by rapid population growth and unplanned urbanization. The growing environmental awareness and water supply restrictions have made rainwater harvesting systems (RWHS) a priority as well as a necessity in many countries. To improve urban water security, the practice of an RWHS is increasingly being adopted in the cities and towns of developing countries. This study aims at identifying the factors affecting the adoption of rainwater harvesting for household uses in the Kathmandu valley (KV) of Nepal. The results were drawn from a survey of 405 respondents who reside in the KV. To explain the determinants of adaptation, structural equation modeling (SEM) was used. Results show that independence for water access and system sophistication are significant for the adaptation of RWHS and relative advantage plays a moderating role that has partial mediation among dependent and independent variables with a significant relationship. Thus, variables like independence for water access, system sophistication, relative advantage and sustainable use should be highlighted for a sustainable supply of water. For this, we recommend effective policy interventions at the local and national level for the adoption of RWHS and its advantages in terms of safeguarding water in the long run at the present changing climate scenario.
Una aproximación a la cosmovisión andina en «Oshta y el duende», de Carlota Carvallo de Núñez
Authors: Aguilar-Ponce Emma
Published: October 2022

El presente trabajo tiene como objetivo analizar la cosmovisión andina (pachasofía), en el cuento «Oshta y el duende», de Carlota Carvallo de Núñez. El análisis se concentra en la estructura tripartita del mundo andino concebido en hanan pacha (mundo de arriba), kay pacha (mundo de aquí) y uku pacha (mundo de abajo). Con respecto al hanan pacha, se analiza los fenómenos atmosféricos. Asimismo, en relación con el kay pacha, se desarrolla la interrelación del hombre y la naturaleza, además la actitud del niño Oshta y su madre Silveria. Por último, el análisis del uku pacha se concentra en el personaje mítico del duende (muqui). Finalmente, se afirma que en el cuento la estructura tripartita de la cosmovisión andina expone ciertas características desde la perspectiva occidental. En este contexto, personajes como el zorro y el puma a través de sus conductas bribonas transgreden la percepción divina en dicha concepción; así como la actitud de la madre al dejar al niño cuidando las ovejas, al ser una labor encomendada al ámbito femenino. Este trabajo se desarrolla apelando principalmente a las reflexiones de Josef Estermann, J.J.M.M. Van Kessel, Carmen Salazar Soler, Francisco Izquierdo Ríos, David Heflin, entre otros.
Are Monocyte, %M and WBC Biomarkers in the First Trimester Screening
Test?
Authors: Oz Ozlem , Gonel Ataman
Published: October 2022

Background:

Differences in free beta HCG and PAPP-A values, which are among the biochemical parameters in the double screening test, is frequently used for pregnancy follow-up, allow aneuploidy and triploidy risk to be determined. In recent studies, it’s suggested that the modified hemogram indices have gained importance as a marker in the prognosis of diseases.

Objective:

In this study, we aimed to determine the hematological parameters, which are routinely applied in the first trimester of pregnancy, have any value in predicting the risk increase in the double screening test and in early diagnosis.

Method:

Pregnant women who conceived spontaneously and had double screening tests were included in the study. CBC results that were studied together with the first trimester screening test were reported. The patients were divided into two groups according to the results of the screening test as the combined risk ratio.

Results:

The mean age was found to be significantly higher in the high-risk group than in the low-risk group. Monocyte, % M and WBC values were significantly lower in the high-risk group (0,483±0,140, 5,58±1,44 and 8,75±2,12 , respectively). There was no significant difference in NLR and PLR values compared between the groups. MPV values were lower and PAPP-A, PAPP-A MoM values were significantly lower in high-risk group compared to the low-risk group.

Conclusion:

The findings support low Monocyte, % M and WBC values as a potential marker for the identification of the high risk pregnancy in otherwise healthy pregnant women. The results indicate that CBC parametres commonly used in pregnancy can be used to predict the prognosis.
Effectiveness of Selective Estrogen Receptor Modulators in Breast
Cancer Therapy: An Update
Authors: Das Agnidipta , Lavanya Kanamarlapudi Joshna , Nandini  , Kaur Kamalpreet , Jaitak Vikas
Published: October 2022

Background:

Breast cancer is considered to be 2nd most common cancer subtype
investigated worldwide. It is mainly prevalent in postmenopausal women. Estrogen
Receptor (ER) is a primary transcription factor for the survival and growth of tumors.
Around 80% BCs of all classes are ER-positive (ER+). Powerful evidence for estrogen
proved to be involved in BC pathogenesis both exogenously and endogenously. It brings
the concept of ER inhibitors to treat BC with distinct mechanisms into focus and ER
PROTACs (Proteolysis-Targeting Chimeras), AIs (Aromatase inhibitors), SERMs (Selective
estrogen receptor modulators), and SERDs (Selective estrogen receptor degrader)
were developed. For over 30 years, Tamoxifen, a triphenylethylene SERM, was the drug
of choice solely to treat ER+BC patients. Although several SERMs got approval by US
FDA after tamoxifen, complicacies remain because of dangerous adverse effects like endometrial
carcinoma, hot flashes, and VTE (Venous thromboembolism). In addition to
that, drug-resistant tumors put a surging need for novel, potent candidates with no or low
adverse effects for ER+ BC prevention.

Objectives:

This article explores the possibilities of SERMs as effective BC agents.

Methods:

A detailed literature survey of the history and recent advancements of SERMs
has been carried out, taking BC as the primary target. This review provides information
about ER structure, signaling, pharmacological action, chemical classification with SAR
analysis, and benefits and adverse effects of SERMs as potential BC agents.

Results:

Exhaustive literature studies suggested that SERMs having an agonistic, antagonistic
or mixed activity to ER could efficiently inhibit BC cell proliferation

Conclusion:

Each chemical class of SERMs comprises some salient features and potentials,
which may be further investigated to obtain novel effective SERMs in BC therapy.
A Revision of Polymeric Nanoparticles as a Strategy to Improve the
Biological Activity of Melatonin
Authors: Franco Pablo Igor Ribeiro , do Carmo Neto José Rodrigues , Rocha Viviane Lopes , Machado Juliana Reis , Amaral Andre Correa , Miguel Marina Pacheco
Published: October 2022

Drug delivery systems based on nanotechnology exhibit a number of advantages
over traditional pharmacological formulations. Polymeric nanoparticles are commonly
used as delivery systems and consist of synthetic or natural polymers that protect
drugs from degradation in physiological environments. In this context, indolamine melatonin
has been associated with several biological functions, including antioxidant, antitumor,
immunoregulatory, neuroprotective, and cardioprotective effects. However, its availability,
half-life, and absorption depend upon the route of administration, and this can limit
its therapeutic potential. An alternative is the use of polymeric nanoparticle formulations
associated with melatonin to increase its bioavailability and therapeutic dose at sites
of interest. Thus, the objective of this review is to provide a general and concise approach
to the therapeutic association between melatonin and polymeric nanoparticles applied
to different biological disorders and to also highlight its advantages and potential
applications compared to those of the typical drug formulations that are available.
Role of PPAR in the Pharmacological Regulation of Lipoprotein Metabolism by Fibrates and Thiazolidinediones
Authors: Staels Bart , Auwerx Johan
Published: October 2022

The peroxisome proliferator activated receptors or PPARs constitute a subfamily of the nuclear hormone receptor superfamily of transcription factors. PPARs form heterodimeric complexes with the 9-cis retinoic acid receptor (RXR), which bind to specific response elements, termed peroxisome proliferator response element (PPRE), located in the regulatory regions of target genes. As such they modulate the transcri­ ptional activity of genes, the majority of which are involved in lipid and lipoprotein metabolism. To date three PPAR variants, a, (◊) and y, have been identified, each displaying a specific tissue distribution pattern. Although the function of the PPARO variant remains unknown, evidence coming from different rodent model systems indicates
that the PPARa plays a crucial role in hepatic lipid metabolism, whereas PPARy participates in adipocyte differentiation and function. Although only for PPARy natural (prostaglandin J2) and synthetic (the thiazolidinedione BRL 49653) ligands have been identified sofar, all PPARs are activated by a wide variety of chemicals amongst which the hypolipidemic drugs fibrates and the antidiabetic thiazolidinediones. Evidence is now accumulating that the hypotriglyceridemic action of fibrates in humans is primarily mediated via activation of PPARa in liver resulting in the repression of the expression of apo C-III, a key-player in plasma triglyceride metabolism. In addition the high density lipoprotein (HDL)-raising activity of fibrates is linked to a PPARa- mediated induction of the major HDL apolipoproteins, apo A-I and apo A-II in liver. By contrast, whereas the link between PPARy activation and glucose metabolism is still unclear, the antidiabetic thiazolidinediones exert a potent hypotriglyceridemic action via the induction of lipoprotein lipase (LPL) expression in adipose tissue. Due to the involvement of different PPAR variants, fibrates and thiazolidinediones act through distinct and complementary mechanisms on plasma triglyceride metabolism. The identification of the molecular mechanism of action of these pharmacological agents, and the role distinct transcription factors of the PPAR family play therein, suggests that compounds activating both PPARa and PPARy should be very potent hypotriglyceridemic drugs, which may be of use in the treatment of the dyslipidemia associated with atherosclerosis and non-insulin dependent diabetes mellitus.