bluuebunny/crossref_metadata_2025 huggingface dataset:
Identifying the Multitarget Pharmacological Mechanism of Action of Genistein on Lung Cancer by Integrating Network Pharmacology and Molecular Dynamic Simulation
Authors: Das Raju , Woo Joohan
Published: April 2024

Food supplements have become beneficial as adjuvant therapies for many chronic disorders, including cancer. Genistein, a natural isoflavone enriched in soybeans, has gained potential interest as an anticancer agent for various cancers, primarily by modulating apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis. However, in lung cancer, the exact impact and mechanism of action of genistein still require clarification. To provide more insight into the mechanism of action of genistein, network pharmacology was employed to identify the key targets and their roles in lung cancer pathogenesis. Based on the degree score, the hub genes AKT1, CASP3, EGFR, STAT3, ESR1, SRC, PTGS2, MMP9, PRAG, and AR were significantly correlated with genistein treatment. AKT1, EGFR, and STAT3 were enriched in the non-small cell lung cancer (NSCLC) pathway according to Kyoto Encyclopedia of Genes and Genomes analysis, indicating a significant connection to lung cancer development. Moreover, the binding affinity of genistein to NSCLC target proteins was further verified by molecular docking and molecular dynamics simulations. Genistein exhibited potential binding to AKT1, which is involved in apoptosis, cell migration, and metastasis, thus holding promise for modulating AKT1 function. Therefore, this study aimed to investigate the mechanism of action of genistein and its therapeutic potential for the treatment of NSCLC.
Isolation and Structure Analysis of Chitin Obtained from Different Developmental Stages of the Mulberry Silkworm (Bombyx mori)
Authors: Jędrzejczak Eryk , Frąckowiak Patrycja , Sibillano Teresa , Brendler Erica , Giannini Cinzia , Jesionowski Teofil , Wysokowski Marcin
Published: April 2024

Chitin, a ubiquitous biopolymer, holds paramount scientific and economic significance. Historically, it has been primarily isolated from marine crustaceans. However, the surge in demand for chitin and the burgeoning interest in biopolymers have necessitated the exploration of alternative sources. Among these methods, the mulberry silkworm (Bombyx mori) has emerged as a particularly intriguing prospect. To isolate chitin from Bombyx mori, a chemical extraction methodology was employed. This process involved a series of meticulously orchestrated steps, including Folch extraction, demineralization, deproteinization, and decolorization. The resultant chitin was subjected to comprehensive analysis utilizing techniques such as attenuated total reflectance–Fourier transform infrared spectroscopy (ATR-FTIR), 13C nuclear magnetic resonance (NMR) spectroscopy, and wide-angle X-ray scattering (WAXS). The obtained results allow us to conclude that the Bombyx mori represents an attractive alternative source of α-chitin.
Formulation and Characterization of Soybean Oil-in-Water Emulsions Stabilized Using Gelatinized Starch Dispersions from Plant Sources
Authors: Singh Ankita , Umeda Takumi , Kobayashi Isao
Published: April 2024

Consumers are concerned about employing green processing technologies and natural ingredients in different manufacturing sectors to achieve a “clean label” standard for products and minimize the hazardous impact of chemical ingredients on human health and the environment. In this study, we investigated the effects of gelatinized starch dispersions (GSDs) prepared from six plant sources (indica and japonica rice, wheat, corn, potatoes, and sweet potatoes) on the formulation and stability of oil-in-water (O/W) emulsions. The effect of gelatinization temperature and time conditions of 85–90 °C for 20 min on the interfacial tension of the two phases was observed. Emulsification was performed using a primary homogenization condition of 10,000 rpm for 5 min, followed by high-pressure homogenization at 100 MPa for five cycles. The effects of higher oil weight fractions (15–25% w/w) and storage stability at different temperatures for four weeks were also evaluated. The interfacial tension of all starch GSDs with soybean oil decreased compared with the interfacial tension between soybean oil and water as a control. The largest interfacial tension reduction was observed for the GSD from indica rice. Microstructural analysis indicated that the GSDs stabilized the O/W emulsion by coating oil droplets. Emulsions formulated using a GSD from indica rice were stable during four weeks of storage with a volume mean diameter (d4,3) of ~1 µm, minimal viscosity change, and a negative ζ-potential.
Functional Activity of Enantiomeric Oximes and Diastereomeric Amines and Cyano Substituents at C9 in 3-Hydroxy-N-phenethyl-5-phenylmorphans
Authors: Roth Hudson G. , Das Madhurima , Sulima Agnieszka , Luo Dan , Kaska Sophia , Prisinzano Thomas E. , Kerr Andrew T. , Jacobson Arthur E. , Rice Kenner C.
Published: April 2024

The synthesis of stereochemically pure oximes, amines, saturated and unsaturated cyanomethyl compounds, and methylaminomethyl compounds at the C9 position in 3-hydroxy-N-phenethyl-5-phenylmorphans provided μ-opioid receptor (MOR) agonists with varied efficacy and potency. One of the most interesting compounds, (2-((1S,5R,9R)-5-(3-hydroxyphenyl)-2-phenethyl-2-azabicyclo[3.3.1]nonan-9-yl)acetonitrile), was found to be a potent partial MOR agonist (EC50 = 2.5 nM, %Emax = 89.6%), as determined in the forskolin-induced cAMP accumulation assay. Others ranged in potency and efficacy at the MOR, from nanomolar potency with a C9 cyanomethyl compound (EC50 = 0.85 nM) to its totally inactive diastereomer, and three compounds exhibited weak MOR antagonist activity (the primary amine 3, the secondary amine 8, and the cyanomethyl compound 41). Many of the compounds were fully efficacious; their efficacy and potency were affected by both the stereochemistry of the molecule and the specific C9 substituent. Most of the MOR agonists were selective in their receptor interactions, and only a few had δ-opioid receptor (DOR) or κ-opioid receptor (KOR) agonist activity. Only one compound, a C9-methylaminomethyl-substituted phenylmorphan, was moderately potent and fully efficacious as a KOR agonist (KOR EC50 = 18 nM (% Emax = 103%)).
Influence of Organic Impurities on Fractional Crystallization of NaCl and Na2SO4 from High-Salinity Coal Chemical Wastewater: Thermodynamics and Nucleation Kinetics Analysis
Authors: Shen Bo , Zhao Bo , Du Hai , Ren Yongsheng , Tang Jianwei , Liu Yong , Hua Quanxian , Wang Baoming
Published: April 2024

It is a valid path to realize the zero discharge of coal chemical wastewater by using the fractional crystallization method to recycle the miscellaneous salt in high-salinity wastewater. In this study, the thermodynamics and nucleation kinetics of sodium chloride (NaCl) and sodium sulfate (Na2SO4) crystallization in coal chemical wastewater were systematically studied. Through analyses of solubility, metastable zone width, and induction period, it was found that the impurity dimethoxymethane would increase the solid–liquid interface energy and critical crystal size during the nucleation of Na2SO4. Ternary phase diagrams of the pseudo-ternary Na2SO4-NaCl-H2O systems in simulated wastewater were plotted in the temperature range of 303.15 to 333.15 K, indicating that a co-ionization effect existed between NaCl and Na2SO4, and NaCl had a strong salting out effect on Na2SO4. Finally, the nucleation rate and growth rate of Na2SO4 crystals under simulated wastewater conditions were determined by the intermittent dynamic method, and the crystallization kinetic models of Na2SO4 were established. The crystallization nucleation of Na2SO4 crystals was found to be secondary nucleation controlled by surface reactions. The basic theoretical research of crystallization in this study is expected to fundamentally promote the application of fractional crystallization to realize the resource utilization of high-salinity wastewater in the coal chemical industry.
Meta-Substituted Asymmetric Azobenzenes: Insights into Structure–Property Relationship
Authors: Sanna Anna Laura , Pachova Tatiana , Catellani Alessandra , Calzolari Arrigo , Sforazzini Giuseppe
Published: April 2024

This article presents a comprehensive investigation into the functionalization of methoxyphenylazobenzene using electron-directing groups located at the meta position relative to the azo group. Spectroscopic analysis of meta-functionalized azobenzenes reveals that the incorporation of electron-withdrawing units significantly influences the absorption spectra of both E and Z isomers, while electron-donating functionalities lead to more subtle changes. The thermal relaxation process from Z to E result in almost twice as prolonged for electron-withdrawing functionalized azobenzenes compared to their electron-rich counterparts. Computational analysis contributes a theoretical understanding of the electronic structure and properties of meta-substituted azobenzenes. This combined approach, integrating experimental and computational techniques, yields significant insights into the structure–property relationship of meta-substituted asymmetrical phenolazobenzenes.
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review
Authors: Bononi Giulia , Lonzi Chiara , Tuccinardi Tiziano , Minutolo Filippo , Granchi Carlotta
Published: April 2024

The phenyl(piperidin-4-yl)methanone fragment (here referred to as the benzoylpiperidine fragment) is a privileged structure in the development of new drugs considering its presence in many bioactive small molecules with both therapeutic (such as anti-cancer, anti-psychotic, anti-thrombotic, anti-arrhythmic, anti-tubercular, anti-parasitic, anti-diabetic, and neuroprotective agents) and diagnostic properties. The benzoylpiperidine fragment is metabolically stable, and it is also considered a potential bioisostere of the piperazine ring, thus making it a feasible and reliable chemical frame to be exploited in drug design. Herein, we discuss the main therapeutic and diagnostic agents presenting the benzoylpiperidine motif in their structure, covering articles reported in the literature since 2000. A specific section is focused on the synthetic strategies adopted to obtain this versatile chemical portion.
Confiabilidade da escala de usabilidade de tecnologia de comunicação aumentativa
Authors: Ferreira Letícia Simões , Portes Leslie Andrews , Santos Vagner Rogério dos , Favero Francis Meire , Oliveira Acary Souza Bulle de
Published: April 2024

Introdução. A usabilidade é definida como o ajuste de um produto às necessidades do usuário, sendo que a avaliação dessa é a interação entre eles. Objetivo. Avaliar a confiabilidade da escala de usabilidade para tecnologia de comunicação aumentativa. Método. Aleatoriamente, 24 participantes, sendo 12 com Esclerose Lateral Amiotrófica e 12 sem a doença, participaram deste estudo. Os participantes passaram por um teste com o teclado inteligente multifuncional e responderam a escala de usabilidade, composta por domínios gerais e específicos relacionados a embalagem, manual de instruções, instalação e utilização da determinada tecnologia. Foi utilizada uma escala psicométrica com pontuação que varia de 0 a 3, gerando um escore de usabilidade. Para a confiabilidade da escala, utilizou-se o programa SPSS versão 24 para o cálculo do Alfa de Cronbach. Resultado. É considerada aceitável uma confiabilidade acima de α 0,5. A escala apresentou uma confiabilidade de α 0,514 para os domínios gerais e α 0,657 para o domínio específico. O teclado inteligente apresentou-se como ”regular” pelos dois grupos, sem diferença estatisticamente significante (p 0,94). Conclusão. A escala apresentou confiabilidade aceitável, sendo capaz de mensurar a usabilidade de uma tecnologia de comunicação aumentativa classificando-a em um escore importante, tanto para o usuário final quanto para a empresa que a confecciona, evitando dispêndios desnecessários e promovendo boa aceitação por parte do usuário, além de auxiliar o profissional na seleção de uma tecnologia mais adequada para seu paciente.
Impact of conflict evolution and geostrategy on national resilience of a nation
Authors: Ayumaesti Adelia , Ediyon Suryo
Published: April 2024

National resilience is the ability of a nation to maintain the survival of its country and state. Various factors, including conflict evolution and geostrategy, influence national resilience. The evolution of conflict and geostrategy can positively or negatively impact national resilience. On the positive side, the evolution of conflict and geostrategy can encourage increased national resilience. This can happen if the evolution of conflict and geostrategy encourages increased national awareness, social cohesion and national defense capabilities. On the negative side, the evolution of conflict and geostrategy can threaten national security. This can happen if the evolution of conflict and geostrategy leads to national disintegration, political destabilization, and increased national security threats.
Notes on Galtonia (Hyacinthaceae) and a Description of the New Hybrid Galtonia ×ceredigionis
Authors: Compton James A. , Schrire Brian D.
Published: April 2024

The history and typification of the five species belonging in the genus Galtonia Decne. (Hyacinthaceae) are discussed. Lectotypes are designated for the names Hyacinthus candicans Baker and Ornithogalum saundersiae Baker. The new spontaneous hybrid Galtonia ×ceredigionis J. Compton & Schrire, formed from a natural cross between G. candicans (Baker) Decne. and G. princeps (Baker) Decne., is described.
Penguatan Kompetensi Jaringan Komputer Berbasis Hardware Cisco bagi Siswa Jurusan Teknik Komputer Jaringan SMK Taruna Persada Dumai
Authors: Purwantoro E.S.G.S Sugeng , Novayani Wenda , Fitrisia Yuli , Akbar Memen , Fadli Mardhiah , Nurmalasari Dini , Alim Syahbana Yoada
Published: April 2024

Cisco menjadi standar utama pada dunia jaringan professional dam dunia industri yang secara core bisnisnya kearah IT atau bahkan non-IT. Kebutuhan Kompetensi Jaringan ini juga bukan hanya dirasakan untuk kebutuhan perusahaan atau industri yang bergerak di bidang IT tapi juga non-IT seperti Perbankan, Kesehatan, Entertainment, Military dan masih banyak lagi tersebut dalamnya dunia pendidikan. Pada Sekolah Menengah Kejuruan, khususnya yang memiliki jurusan Teknik Jaringan Komputer (TKJ), kurikulum Cisco sudah menjadi standar acuan yang banyak diadopsi pada kurikulum jurusan TKJ. Bahkan sudah masuk kedalam kurikulum yang wajib dikuasai siswa SMK bidang TJK. Pada Uji Kompetensi (UK) yang harus dijalani siswa pada akhir semester, bahkan perangkat cisco router secara hardware menjadi salah satu bahan uji. Sehingga siswa dan guru SMK saat ini harus bisa menggunakan perangkat Cisco secara hardware. Namun masih banyak Sekolah yang belum memberikan penguasan Hardware kepada siswanya dikarenakan keterbatasan dana untuk mempersiapkan perangkat Hardware. Oleh karena ini kegiatan PkM ini diselenggarakan oleh Program Studi Teknologi Rekayasa Komputer PCR bermitra dengan SMK Taruna Persada Dumai dalam rangka untuk memberikan pemahaman dan pengalaman kepada siswa untuk dapat menggunakan hardware Cisco dari pengenalan secara bentuk fisik perangkat, cara installasi dan konfigurasi pada perangkat sampai verifikasi keterhubungan jaringan komputer dengan perangkat Cisco.
INVOLVEMENT EXCLUSION FOR OFFICERS OF THE SUPERVISION BODIES
Authors:   Main Directorate of the Ministry of Emergency Situations of Russia for the Khanty-Mansiysk Autonomous Okrug – Ugra, Khanty-Mansiysk, Russia, Квитко А. В. , Собещанский Р. А. ,   Main Directorate of the Ministry of Emergency Situations of Russia for the Khanty-Mansiysk Autonomous Okrug – Ugra, Khanty-Mansiysk, Russia
Published: April 2024

The article reveals the relevance and absolute need for introducing a new institution into the criminal legislation of the Russian Federation. The study aims to investigate the aspect of сriminal legal protection of state control (supervision) officers. The main objective of the study is to consider the issue of amending the Criminal Code of the Russian Federation of June 13, 1996 No. 63-FZ (hereinafter referred to as the Criminal Code of the Russian Federation). Methods of empirical research (comparative and legal analysis), synthesis, induction, and deduction were used in the course of the study. As a result of the study, the authors propose a regulation that will ensure state protection for a certain category of officers.
RUSSIA’S BUDGET AND ECONOMIC INSTABILITY IN THE 21st CENTURY
Authors:   Institute of Economics of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia, Судакова А. Е. , Агарков Г. А. ,   Institute of Economics of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russia
Published: April 2024

The beginning of the twenty-first century was marked by various economic crises that affected the economy and changed the state budget structure. The fiscal policy is designed to stabilize the economy by using such tools as automatic and discretionary stabilizers. The work employed statistical analysis methods, specifically region clustering using the k-mean approach, calculating statistical indicators, and assessing budgets with the share calculated by expenditure items and the supplied value by 2005 per capita. Conclusions are made about changes in the structure of expenditures during crises and their response to budgetary policy instruments. At the same time, the cause of the crisis is reflected in the structure of expenditures; for instance, an increase in expenditures on the national economy was noted in 2009, while an increase in healthcare costs happened in 2020. In addition, the classification of regions into clusters did not reveal the specifics of the budget structure, but budget features are observed among regions when they are classified into two categories: high gratuitous receipts (greater than 20 % of income) and moderate (up to 20 % of income). Thus, in regions with a high share of gratuitous receipts, there is an increase in spending on social policy per capita at comparable prices, whereas there is an increase in spending on healthcare regarding the moderate share. The practical significance of the study lies in the possibility of using the results when writing analytical reports for public authorities and developing measures for various stages of the economic cycle.
ECONOMIC SECURITY RISKS MANAGEMENT OF BUSINESS SYSTEMS
Authors:   Kuban State Technological University, Krasnodar, Russia, Хашир Б. О. , Московцева Л. В. ,   Lipetsk Branch of the Russian Presidential Academy of National Economy and Public Administration, Lipetsk, Russia, Корякина Т. В. ,   Financial University under the Government of the Russian Federation, Lipetsk, Russia, Усанов А. Ю. ,   Moscow University for Industry and Finance “Synergy”, Moscow, Russia
Published: April 2024

Nowadays, the amount of uncertainty surrounding the processes of forecasting the further establishment of a business system is increasing, resulting in the need for new approaches for detecting and managing the economic security risks of business systems. The study aims to examine the current risks to the state and regions’ economic security, as well as to develop an efficient tool for managing the risks to business systems in order to improve their adaptability in turbulent periods. The authors set the following objectives: systematization of the economic security risks of business systems at the given stage; examination of the causes and features of current risks affecting the condition of the state’s economic security; and search for managing approaches for risks in order to improve the adaptability of business systems. The authors identified economic sustainability risks, potential development risks, and social welfare risks. They also proposed a system of indicators for detecting existing economic risks. The article analyzed certain indicators of economic security from 2019 to 2021 in order to identify areas of vulnerability in Russian business systems. The ground for the tension and the economic security risks were determined. The authors introduced their own approach for developing a management system for the economic security risks of business systems, including determining a level of uncertainty (high, moderate, or low), a level of risk (high, moderate, or low), and appropriate urgent and strategic measures on the spot.
Francisco de Olmos y Juan de las Heras, artistas de Asiain. Su intervención en Aldaba
Authors: Músquiz Pérez de Zabalza Josetxo
Published: April 2024

El objetivo de esta investigación es dar a conocer al ensamblador de Asiáin Francisco de Olmos II (1606-1687), continuador de una saga familiar cuyo primer eslabón fue su padre, también llamado Francisco de Olmos, y a quien siguió su hijo Francisco Andrés. Se exponen datos inéditos sobre esta familia, integrante de uno de los más pujantes talleres de artistas de Asiáin. Dado que el estudio se enmarca en el proceso de ejecución del retablo mayor de Aldaba, se reflejan también algunos datos inéditos sobre Juan de las Heras, el pintor dorador que intervino en aquella obra. Para todo ello, nos hemos basado en documentación de las notarías de Asiáin y en procesos del Archivo General de Navarra.
Las vicisitudes del autor y la crónica censurada de la Guerra Civil, redactada por el secretario del general Mola, José María Iribarren
Authors: Alli Aranguren Juan Cruz
Published: April 2024

Este artículo recoge el contenido y los sucesos en torno a una crónica de los primeros meses de la Guerra Civil, redactados por José María Iribarren, secretario del general Mola. Tras su edición y distribución se produjo la detención del autor, amenaza de fusilamiento, secuestro y destrucción de la obra por orden del jefe de Prensa y Propaganda del cuartel general de Franco. El trabajo se realiza sobre un ejemplar acotado por el autor. La obra permite conocer las tensiones y los conflictos políticos entre los sublevados civiles y militares, la presencia nazi y fascista, la potenciación de la Falange, la represión y la construcción del régimen.
A Study on Improving Protection for Victims of Sexual Violence According to the Military Court Act Amendment : Focusing on the analysis of laws and guidelines
Authors:   Academy of Social Welfare and Law, Kwon Jun Nam
Published: April 2024

As the number of cases of military sexual violence increases, the conflict between the scope of application by status and the laws related to military sexual violence is very important for protecting victims of sexual violence in the military. However, after the revision of the “Military Court Act”, a systematic review of personnel laws related to victims following the transfer of military sexual assault cases to the private sector and discussions on reorganization of the laws were insufficient.
Accordingly, this study focuses on the revised ‘Military Court Act’,‘Military Personnel Act’, ‘Military Civil Servant Personnel Act’,‘Framework Act on the Status and Service of Soldiers’,‘State Public Officials Act’ and ‘Framework Act on Prevention of Violence against Women’ related to the protection of victims of military sexual violence , ‘Sexual Violence Prevention and Victim Protection Act’, 'Military Criminal Act', such as ‘Enforcement Decree of the Framework Act on the Status of Soldiers’, 'Military Criminal Act', 8 related laws,‘Enforcement Decree of the Framework Act on the Status of Soldiers’,'Enforcement Decree of the Military Civil Servant Personnel Act',‘Unit Management Instruction’, 2 Presidential Decrees and 1 Administrative rule data were analyzed. Through review of related laws and regulations, we reviewed the conflicting limits of the scope of application by status and reporting obligations, and analyzed the 'Secondary Victimization Prevention Guidelines' of 9 government agencies, additional provisions of specific and active secondary victimization prevention guidelines for the protection of victims of sexual violence were discussed. Based on this, measures to improve the laws and guidelines related to the protection of victims of military sexual violence were presented, and through reorganization of related laws and regulations in the future, the unification of military sexual violence personnel related laws and regulations and countermeasures that reflected the special characteristics of the military were discussed.
This study objectively analyzes the application of personnel laws and regulations for victims of sexual violence through the transfer of military sexual violence to the private sector after the revision of the 'Military Court Act' and objectively analyzes the problem of conflicting obligations in the event of a sexual violence incident. It is meaningful in that it was discussed to prepare measures to improve protection.
Welfare Authorities and Responsibilities of Local Government Heads -Focusing on issues related to the operation of self-sufficiency centers under the 「National Basic Living Security Act」-
Authors:   Academy of Social Welfare and Law, Yoon Seok-Jin , Lee Gyeong Eun
Published: April 2024

There is a controversy over the authority to designate and cancel a self-sufficiency centers, which is the Minister of Health and Welfare have under the 「National Basic Living Security Act」. This is because the essential authority belongs to the central government even though basic local governments carry out most of the main tasks of centers installed in metropolitan and basic local governments. It is a problem arising from the confusion of the ideology, principles, and standards of the distribution of authority surrounding welfare affairs.
In details, for the case of self-sufficiency centers, it is appropriate that the head of a local government who have control over area get a core authority to it installed in a metropolitan area or local government. However, in reality, the authority is concentrated in the Minister of Health and Welfare. This situation have a gap with the legislative purpose of the 「Local Autonomy Act」 and 「Special Act On Local Autonomy And Decentralization, And Restructuring Of Local Administrative Systems」.
Since a self-sufficiency business supports self-reliance of the low income class in the local community, it is a task that should fully consider various regional characteristics. As a similar case, most of the designation and declaration systems stipulated in the 「Welfare Of Senior Citizens Act」, 「Act On Activity Assistant Services For Persons With Disabilities」, and 「Social Welfare Services Act」 are established under the authority of local governments. Therefore, the 「National Basic Living Security Act」 also needs to be improved to give the authority to designate and cancel a self-sufficiency centers to heads of metropolitan and basic local governments.
On the other hand, 「National Basic Living Security Act」, which is currently the basis for operating a self-sufficiency centers, have insufficient legislative grounds in regulating entry, operation, and exit of the centers. For this reason, a case suspected unconstitutionality were found due to violation of the jurisprudence of the delegated legislation. It is an issue that requires urgent improvement because it can neutralize the self-sufficiency support business for the low-income class in Korea.
Two-dimensional analysis of the interfacial solvation structure of an ionic liquid electrolyte on a hydrogen-terminated Si electrode by atomic force microscopy
Authors: Ichii Takashi , Itakura Kazuyuki , Bao Yifan , Utsunomiya Toru , Sugimura Hiroyuki
Published: April 2024

Ionic liquids (ILs) have been intensively studied as new electrolytes for lithium-ion batteries (LIBs). Structural analysis of interfaces between an IL-based electrolyte and an LIB electrode would provide beneficial information for improving LIBs. In this study, we investigated the interfacial structures between an IL, 1-methyl-1-propyl-pyrrolidinium bis(trifluoromethanesulfonyl)imide, and a H-terminated Si(111) electrode in the presence and absence of Li salt by frequency modulation atomic force microscopy utilizing a quartz tuning fork sensor. Two-dimensional frequency shift mapping imaging of the solvation structure at the interface showed that the layered solvation structure was only observed in the absence of Li salts in the ILs, which was in good agreement with our previous studies performed on IL/lithium titanate interfaces. Combined with electrochemical measurements, the partial disappearance of the layered solvation structure in the Li salt-doped IL was strongly suggested to be due to the Li-ion insertion/extraction at the IL/Si interface.
A Novel Cycle Leader Permutation with Elgamal Algorithm for Image Encryption
Authors:   Department of Computer Science and Technology, Yogi Vemana University, Kadapa-516005, India., Vadana Boggana , Rao Kanusu. Srinivasa ,   Associate Professor, Department of Computer Science and Technology, Yogi Vemana University, Kadapa, India., Reddaiah Buduri. ,   Department of Computer Science and Technology, Yogi Vemana University, Kadapa, India., Kumar Bodi. Susheel ,   Department of Computer Science and Technology, Yogi Vemana University, Kadapa, India.
Published: April 2024

As more people use networks in whatever capacity, security-related issues come up more frequently. These issues could be external to the network or inside to it. To address the security-related issues The science of cryptography and network security makes it possible to protect the resources, data quality, and network infrastructure. Firewalls and filters are utilized across many workstations to safeguard the resources. However, security services are required to safeguard the data during transmission to prevent unauthorized access. To guard against attacks, these services must be changed often. This paper integrates Cycle Leader permutation with Elgamal algorithms to construct such a system. These hybrid solutions can be used to stop hackers from gaining unauthorized access different commercial applications.
The Specialized Institutional Media and its Functional Role in Shaping the Mental Image of the Institutional Audience
Authors:   College of Mass Communication and Public Relations, University of Fujairah, Emirate of Fujairah, United Arab Emirates., Abdalaziz Dr. Maha Mustafa Omer
Published: April 2024

There is confusion between the use of the concept of the mental image, the stereotype, the impression image, the inverted image, and the inverted patterns of the areas and patterns of specialized media influence in how to build and shape the mental image of the institutional audience, which will be discussed in this paper. The specialized institutional media and its functions have a role in shaping the mental image of the institutional audience through its patterns. The various media and functionalities represented in their various means and dedicated to these institutions have become considered among the means used in drawing the complex mixture of beliefs, ideas, and impressions that these institutions form among their audiences. The more these institutions can employ the means of knowledge of the public by drawing a mental image of the institution to which they belong, the more they can draw a clearer picture with multiple angles that can convey information to the public through its public or private institutional media. The importance of this paper comes from the transformation brought about by the specialized media in the possibility of shaping the mental image of the different sectors of society through what the specialized institutional media offers to the audience of institutions through the means of communication and communication through them; And the important role in forming opinions, making decisions and shaping behavior through good performance that is consistent with the needs of the public affecting and affected by the policy of the individual or institution. Therefore, the paper focused on the attention given to the subject of the mental image in many media, psychological, social, and administrative studies, and given the pivotal role that the mental image plays in influencing the areas of institutional media influence, from an influential role in our behaviors, decisions and daily lives, to that extent of benefiting from this transformation The similar integrated digital networks, which in turn caused a huge shift in the concept of specialized institutional media and the extent of its influence in shaping the mental image of the various sectors of society, especially the institutional audience, and what the media outlets aim in their specialized institutional media in the presence of an environment that allows them to achieve their goals, perform their mission and provide their services from During the process of modifying, building and shaping the mental image that requires multiple media efforts and how to benefit from it.
Economic resilience and macroeconomic imbalances: the impact of structural policy
Authors: Rozhkovskaya Ekaterina
Published: April 2024

Currently, global transformation processes are intensifying, causing increased uncertainty and volatility in economic dynamics. Under these conditions, there is an increasing need to raise economic resilience, which is a condition for maintaining stable growth dynamics, and is considered the ability of the economic system to absorb shocks and quickly adapt to changes in external and internal conditions. The most important condition for ensuring economic resilience is maintaining macroeconomic balance and counteracting the growth of excessive imbalances. The purpose of this research is to identify factors and mechanisms for the formation of macroeconomic imbalances, establish their relationship with economic resilience, and determine general approaches to economic policy for the adjustment of imbalances. The methods used in this research are analysis, synthesis, comparison, and generalization. Some of the conclusions that emerged from the research are as follows. Macroeconomic imbalances manifest themselves not only in the disruption of foreign economic equilibrium, but also in a slowdown in economic growth, internal recession, increased inflation, and a decrease in the global competitiveness of the economy. In most economies, external and internal imbalances are stable, and chronic, and attempts to combat them can lead to their transformation, but do not eliminate them. Constant macroeconomic imbalances are caused by inertial factors: the specifics of the development model of the national economy, structural disproportions, and the fight against which regular macroeconomic policy (monetary, fiscal) is ineffective. An effective tool for adjusting macroeconomic and structural imbalances is structural policy. It has been established that the influence of structural policy on macroeconomic balance and resilience is realized through the following channels: increasing the efficiency and competitiveness of production, raising mobility of production factors and reallocation of resources; and improvement of self-regulation mechanisms of the economic system.
Methodological and scientific contribution to the development of the pigmeat sector based on standard development projects
Authors: Baltag Grigore , Osoianu Alexandru
Published: April 2024

Starting a business requires a complex and thoughtful approach to everyone who wants business involvement. The deep attitude towards all elements of the business must be recognized by their importance to each founder. The business to be initiated cannot be achieved by a general approach or based on the current pace of evolution and so on. A business at the stage of knowledge, must be studied through its subtleties, specific technologies, links, and stages of operation, so that the investor is initiated and self-trained in the best way. To be capitalized, the business idea is transformed into a business through a plan developed by the investor, which establishes the investment stages, financing, employment processes and other elements, so that at the beginning of the technological process the stages of investment, construction, acquisition, and technical arrangements are solved and prepared. Only a good training from a theoretical point of view can ensure the success of an entrepreneur in developing the identified business. The investment project comes to the aid of all those interested in starting businesses in rural areas and is intended for the livestock branch. The project is dedicated to raising pigs for meat with the provision of good practices and environmental friendliness. In this investment project are described the basic peculiarities of the pig business, the technological elements of ensuring the technological process, the development factors and the economic results pursued. Through this project, investors and businessmen who want to start agricultural businesses can assess their economic capabilities and draw inspiration from factological content.
Development of sour cherry production in the Republic of Moldova
Authors: Ceban Alexandru , Lucasenco Eugenia
Published: April 2024

Sour cherries represent one of the most important Moldovan fruits grown in the Republic of Moldova, with a great potential for modernization and further development of production. There is noticed a slow grow in terms of surface, as well as production and averge yield per hectare for sour cherries. At the same time, exports account for about 19% of the total production. Compared to world exports, sour cherry production in the Republic of Moldova possesses a very high Revealed Comparative Advantage index. Therefore, the purpose of this paper is to carry out an analysis of sour cherry production in the Republic of Moldova, to analyze the current situation, development trends as well as the degree of international competitiveness for the given product with respect to the world trade. Thus, the research methods selected and used for the given article refer to the analytical, descriptive, comparative method, as well as through the Revealed Comparative Advantage indicator. Although the demand for sour cherries is increasingm, there are some existing issues in the field that need to be addressed in order to have a successful horticultural business. At the same time, the paper presents a specific argumentation for the existence of a development potential of this sub-sector in order to persuade farmers to get engaged in this specific activity.
Representation of a Noisy Transmission Line
Authors: Bucher Martin , Molnar Daniel
Published: April 2024

We analyse a lossy transmission line and the Johnson-Nyquist noise generated therein. A representation as a noisy two-port with a voltage and a current noise sources on one end of a noiseless two-port is given. An expression for the noise properties is given for an arbitrary temperature profile along the transmission line. Compatibility of the general expression found here with expectations for special cases calculable using thermodynamics is demonstrated.
KAM-PaY: Closed Wallet with SQL-Technology and Biometric Authentication
Authors: M Rajasekaran , C Vetri Venthan , G Prem Kumar , M Ragesh
Published: April 2024

Closed Wallet is a novel database collection system designed to securely gather and manage user data using SQL technology. This system addresses the growing concern for data privacy and security by implementing robust authentication methods and access controls. Through SQL queries, Closed Wallet efficiently retrieves and stores user information while adhering to stringent privacy regulations. The proposed KAM-Pay (Kamaraj payment), an implementation of the closed e-wallet system for the college canteen in Kamaraj Engineering college, is being developed using Visual Studio. Furthermore, the biometric authentication in proposed work ensures the data integrity and confidentiality, safeguarding sensitive information from unauthorized access.
PENGARUH BEBAN KERJA DAN TUNJANGAN PROFESI TERHADAP KEPUASAN KERJA GURU MADRASAH TSANAWIYAH DI KABUPATEN TANAH LAUT
Authors: Alfianoor Alfianoor , Abdurrahman Akhmad
Published: April 2024

ALFIANOOR (2019) This study aims to (1) analyze the effect of workload on job satisfaction. (2) analyze the effect of professional allowances on job satisfaction. (3) analyze the effect of workload and professional allowances simultaneously on job satisfaction for Madrasah Tsanawiyah teachers in Tanah Laut Regency. The design of this study is based on a survey approach whose nature of this research is explanatory is a study that intends to explain the position of the variables studied and the relationship between one variable and another. The existing research variables are to predict the closeness of the influence of one to the other variables according to the criteria concerning the influence of workload and professional allowances on job satisfaction of teachers in the Madrasah Tsanawiyah Regency in Tanah Laut in a strong and in-depth manner using multiple regression analysis. The population were all 98 Madrasah Tsanawiyah teachers in Tanah Laut Regency. The sampling technique is Porpusive Sampling which is determined in advance and has a relationship with the study, which is as many as 42 ASN people at the Madrasah Tsanawiyah Negeri in Tanah Laut Regency who have received certification allowances. Data was collected through questionnaires and documentation. The analytical tool used in this study is descriptive statistical analysis and inferential statistical analysis with SPSS 20.0 for Windows. The results of the study show that (1) The effect of workload on job satisfaction of Madrasah Tsanawiyah teachers in Tanah Laut Regency based on the results of the t test is known that t count> t Table can be declared significant and proven. (2) That the results show the existence of professional allowances have a significant effect on teacher job satisfaction. (3) Workload and professional allowances have a significant effect simultaneously (together) on job satisfaction of Madrasah Tsanawiyah Teachers in Tanah Laut Regency based on the results of the F test known that F count> F Table. The better the workload given to Madrasah Tsanawiyah teachers in Tanah Laut District, the higher the level of job satisfaction. Keywords: Workload, Professional Allowance, Teacher Job Satisfaction
IMPLEMENTASI UNDANG-UNDANG REPUBLIK INDONESIA NOMOR 22 TAHUN 2009 TENTANG LALU LINTAS DAN ANGKUTAN JALAN (STUDY TERHADAP PASAL 106 PADA WILAYAH HUKUM KEPOLISIAN RESORT HULU SUNGAI UTARA)
Authors: Gunade Djayeng Turano
Published: April 2024

Implementasi Undang-Undang Republik Indonesia Nomor 22 Tahun 2009 tentang Lalu Lintas dan Angkutan Jalan pada Pasal 106 di Wilayah Hukum Kepolisian Resort Hulu Sungai Utara yang baik dengan berfacu pada empat indikator, yakni komunikasi, sumber daya, disposisi, dan struktur birokrasi sangat diharapkan. Berdasarkan pernyataan tersebut, maka tujuan dalam penelitian ini, yaitu untuk mengetahui implementasi Undang-Undang Republik Indonesia Nomor 22 Tahun 2009 tentang Lalu Lintas dan Angkutan Jalan (Study terhadap Pasal 106 pada Wilayah Hukum Kepolisian Resort Hulu Sungai Utara)

Penelitian ini menggunakan tipe deskriptif-kualitatif dan untuk teknik pengumpulan data dilakukan dengan cara wawancara, observasi, serta dokumentasi. Adapun teknik analisis data menggunakan reduksi data, display data, dan verifikasi data.

Hasil penelitian ini menunjukkan, bahwa Implementasi Undang-Undang Republik Indonesia Nomor 22 Tahun 2009 tentang Lalu Lintas dan Angkutan Jalan (Study terhadap Pasal 106 pada Wilayah Hukum Kepolisian Resort Hulu Sungai Utara) dikaterorikan cukup, karena; 1) Undang-undang tidak disampaikan kepada anggota. 2) Undang-undang tidak disampaikan secara rinci dan jelas. 3) Polantas tidak konsisten menyampaikannya. 4) Beberapa orang staf dan anggota tidak paham pekerjaannya. 5) Undang-undang tidak diberitahukan kepada anggota. 6) Pimpinan tidak mengawasi anggotanya. 7) Fasilitas pengimplementasian tidak lengkap. 8) Polantas mengangkat anggotanya secara ketat. 9) Polantas memberikan insentif kepada anggotanya berprestasi. 10) Polantas menyesuaikan pekerjaan anggotanya. 11) Polantas tidak bekerja sama dengan pihak lain.

Ada beberapa saran yang penulis sampaikan kepada pihak-pihak terkait pada penelitian ini, di antaranya; 1) Penyampaian tentang pekerjaan yang dikerjakan oleh atasan kepada bawahan hendaknya dilakukan. 2) Sebuah kebijakan sebelum diterapkan atau diimplementasikan hendaknya disosialisasikan terlebih dahulu. 2) Kekonsistenan terhadap pengimplementasian dari suatu kebijakan hendaknya dilakukan. 3) Pemahaman terhadap pekerjaan yang dikerjakannya hendaknya dilakukan. 4) Pengawasan oleh pimpinan di dalam bertugas hendaknya dilakukan. 5) Kelengkapan fasilitas hendaknya dilakukan. 6) Pengimplementasian suatu kebijakan hendaknya ada mempunyai hubungan atau kerja sama dengan pihak lain. 7) Kepatuhan terhadap kebijakan hendaknya dilakukan. Adapun untuk masyarakat Kabupaten Hulu Sungai Utara diharapkan mematuhi segala tata tertib di dalam menggunakan jalan raya, khususnya di dalam menggunakan alat transformasinya.
KUALITAS PELAYANAN PROGRAM PENDIDIKAN NON FORMAL KELOMPOK BELAJAR (KEJAR) PAKET C SETARA SMA DI SANGGAR KEGIATAN BELAJAR (SKB) KABUPATEN HULU SUNGAI UTARA
Authors: Barkatullah Barkatullah
Published: April 2024

Tujuan penelitian ini untuk mengetahui kualitas pelayanan Program Pendidikan Non Formal Kelompok Belajar (KEJAR) Paket C Setara SMA Di Sanggar Kegiatan Belajar Kabupaten Hulu Sungai Utara dan faktor yang menghambat. Penelitian ini menggunakan pendekatan kualitatif dengan tipe penelitian deskriftif-kualitatif.

Hasil dari penelitian menunjukkan bahwa kualitas pelayanan pada Sanggar Kegiatan Belajar Kabupaten Hulu Sungai Utara cukup baik dilihat dari tangibles (bukti fisik) meliputi; kondisi fasilitas Sanggar Kegiatan Belajar (SKB) tergolong cukup baik, teknologi penunjang proses belajar mengajar tergolong kurang baik, reliability (kehandalan) meliputi; ketepatan waktu masih tergolong kurang baik, pelayanan sudah cukup baik dengan selalu memberikan pelayanan yang sama kepada seluruh masyarakat, Akurasi guru/tutor cukup baik,  responsiveness (ketanggapan) meliputi; pelayanan yang cepat masih kurang baik, penyampaian informasi yang kurang baik, Assurance (jaminan dan kepastian) meliputi; komunikasi (communication) cukup baik, kredibilitas (credibility) petugas pelayanan cukup baik, keamanan (security) cukup baik, kompetensi guru/tutor kurang baik, sikap ramah dan sopan santun petugas cukup baik, empathy (perhatian) yang meliputi; sikap perhatian petugas cukup baik, rasa nyaman dan kemudahan bagi masyarakat cukup baik. Faktor penghambat kualitas pelayanan meliputi kurang memadainya sarana informasi pelayanan dan tidak sesuainya jadwal pelaksanaan kegiatan belajar mengajar. Upaya yang dilakukan mengatasi hambatan meliputi penyediaan sarana informasi pelayanan dan penambahan tenaga pendidik atau tutor.
PELAKSANAAN PERATURAN DAERAH NO 7 TAHUN 2021 TENTANG RETRIBUSI JASA UMUM STUDI KASUS RETRIBUSI PELAYANAN PERSAMPAHAN KEBERSIHAN PADA PASAR INDUK AMUNTAI KABUPATEN HULU SUNGAI UTARA
Authors: Riadi Selamat , Ahdiat Riswandi , Hidayatullah Gusti Muhammad
Published: April 2024

Penelitian ini bertujuan untuk mengetahui bagaimana implementasi kebijakan tersebut berjalan dan apa faktor yang menghambat implementasi kebijakan retribusi pelayanan persampahan kebersihan di pasar induk Amuntai. Penelitian ini menggunakan pendekatan kualitatif dengan teknik pengumpulan data dari hasil observasi, wawancara dan dokumentasi. Hasil penelitian ini menunjukkan bahwa dalam pelaksanaan peraturan daerah  no 7 tahun 2021 tentang retribusi jasa umum studi kasus retribusi  pelayanan persampahan kebersihan pada pasar induk Amuntai kabupaten Hulu Sungai Utara sudah cukup baik hal ini dilihat dari indikator-indikator : Kemampuan Organisasi, Informasi, Dukungan. dan Pembagian Potensi. Sedangkan kendala yang dihadapi yaitu : Adanya pemungutan pembayaran (iuran), kurangnya kesadaran masyarakat dalam mematuhi kebijakan retribuasi, dan kurangnya sumber daya SDM serta sarana dan prasarana masih kurang