bluuebunny/crossref_metadata_2025 huggingface dataset:
A rare case of simultaneous multifocal craniospinal hemangiopericytomas
Authors: Singh Harnarayan , Patir Rana , Gupta Anurag , Vaishya Sandeep
Published: January 2022

First reported case of simultaneous occurrence of hemangiopericytomas(HCP) at multiple sites of craniospinal axis in a thirty four year male is presented. Patient presented with neck pain for 1 year, and one episode of simple partial seizure involving his left lower limb. He was diagnosed as having HCP in right middle one third parasagittal region, and C4,5 vertebral bodies. Another lesion was present in L5 vertebra, which was radiologically similar to the cervical lesion, but not biopsy proven. High index of suspicion, and low threshold for screening, for coexistence of spinal HCP, in patients harboring cranial HCP's and complaints of back pain.
Natural history of medulloblastoma in a child with neurofibromatosis type I
Authors: Golpayegani Mehdi , Salari Farhad , Habibi Zohreh , Anbarlouei Mousarreza , Mahdavi Ali , Nejat Farideh
Published: January 2022

Medulloblastoma is one of the common posterior fossa tumors in children. The natural history of this tumor in presymptomatic period is not well known. Widespread use of brain imaging has increased the detection of incidental brain tumors in totally asymptomatic persons. Here, we report a case of a 4-year-old boy with prenatal diagnosis of congenital brain abnormalities and neurofibromatosis type I. He underwent regular brain imaging to follow interhemispheric arachnoid cyst and ventriculomegaly that a posterior fossa tumor was discovered. The tumor size increased during time and became symptomatic after 28 months which was resected.
Iatrogenic (Traumatic) occipital artery pseudoaneurysm – Rare complication of ventriculoperitoneal shunt in an infant: Case report and review of the literature
Authors: Elgamal Mohannad , Elgamal Essam , Ahmad Anwar , Elsayed Adham , Younes Basel , Aljaraki Mohammad , Elholiby Tamer
Published: January 2022

Although ventriculoperitoneal shunt (VPS) is the most common procedure performed by pediatric neurosurgeons, it is still associated with frustrating complications, most common of which are obstruction and infection. Traumatic occipital artery pseudoaneurysm is a very rare complication of VPS procedure. To the best of our knowledge, there is no similar case reported in the English language literature. A 12-month-old patient suffered posthemorrhagic hydrocephalus of prematurity, and multiple other complications due to extreme prematurity, including immature lung disease, retinopathy of prematurity, necrotizing enterocolitis, bowel perforation, short bowel syndrome resulting in total parenteral nutrition-dependence, and hydrocephalus which was treated by insertion of VPS. Four weeks after the shunt, a slowly enlarging pulsatile swelling distal to the valve under the catheter altering the shunt function was noted. The swelling was diagnosed as a pseudoaneurysm of the occipital artery and treated by excision of the aneurysm. The child developed isolated dilated fourth ventricle, which was treated by endoscopic fourth ventriculostomy. Traumatic occipital artery pseudoaneurysm as a result of tunneling of VPS catheter is a very rare complication of VPS. Clinical and radiological imaging is diagnostic of the aneurysm. Surgical repair should be considered in such cases. This case report is aimed to raise the awareness among physicians about this rare complication.
Lenvatinib
Authors: Goel Alok , Singla Anshul
Published: January 2022

The discovery and clinical efficacy of imatinib in chronic myeloid leukemia opened a new and interesting avenue of oral small-molecule tyrosine kinase inhibitors. Thereafter, several such molecules with efficacy across multiple tumor types have been discovered. One of the oral multi-kinase inhibitors is lenvatinib, which started its journey in 2008 when it showed efficacy on stem cells in the laboratory setting and was first approved by the United States Food and Drug Administration in August 2015 for the management of radioiodine-refractory differentiated thyroid cancer. Since then, it has been approved for hepatocellular, endometrial, and renal cell carcinomas, and many more trials are underway for lenvatinib in multiple solid tumors, either alone or in combination with immunotherapy. In addition to the robust data on the efficacy of this drug, it is known for its tolerability with different dosing schedules in different tumor types, a feature unique to this drug. Therefore, an in-depth understanding of its mechanism of action, pharmacokinetics, pharmacodynamics, dosage in different tumor types, expected side effects, and predictors of response will go a long way in its safe and appropriate use in the clinics. In this review, we aim to summarize and collate these data in a reader-friendly manner, thus making it a ready reckoner for lenvatinib. We searched the PubMed database for full-text articles on lenvatinib published in the last 10 years using the search terms “lenvatinib,” “hepatocellular carcinoma,” renal cell carcinoma,” “thyroid carcinoma,” “and “endometrial carcinoma”. A total of 1053 studies were identified, of which 60 were included in this review.
Post hoc analysis of the screening log of phase III investigator-initiated randomized clinical trial comparing palliative oral metronomic versus intravenous chemotherapy in head-and-neck cancer
Authors: Dhumal Sachin , Patil Vijay , Noronha Vanita , Joshi Amit , Menon Nandini , Nawale Kavita , Tambe Rupali , Prabhash Kumar
Published: January 2022

Background:

Large number of screen failures in trials often result in delayed drug approvals, an increase in the financial burden for conducting research, and limit the applicability of the study results to patients in the clinic.

Objectives:

This post hoc analysis was aimed at assessing the reasons for screen failures in a phase III, investigator-initiated clinical trial conducted in India.

Materials and Methods:

The study was conducted at the Tata Memorial Center, a tertiary cancer center in Mumbai, India. We maintained a log of all potential study candidates who underwent screening in our outpatient department between May 2016 and January 2020. This included the name of the study subject, hospital registration number, age, and sex. We also recorded the screening date and outcome of the screening process (whether enrolled in the study and if not, the reason for it) along with the number of patients who were finally randomized in the study. We evaluated factors that may have impacted screen failure including age, sex, and performance status (PS).

Results:

A total of 594 patients were screened. Of these, 422 were enrolled and 172 failed screening. Out of the 172 patients who were not enrolled, 105 (61%) did not meet the eligibility criteria and 67 (39%) refused to participate due to various reasons. The reasons for non-enrollment in the trial included the lack of a place to stay in Mumbai (35, 20.3%), patient wanted only a particular therapy (16, 9.3%), age over 70 years (15, 8.7%), poor PS (4, 2.3%), deranged organ function (13, 7.6%), active tuberculosis (2, 1.2%), primary tumor in the nasopharynx/thyroid/salivary gland/unknown primary (31, 18%), positivity for viral markers of infection (12, 7%), platinum-refractory disease (23, 13.4%), unwillingness to participate in research (15, 8.7%), patient not willing as they were not accompanied by a relative=1(0.06%) and other reasons (5, 2.9%). Age over 60 years (P = 0.001), and poor PS (P < 0.001) significantly increased the screen failure rate.

Conclusion:

The most common cause for screen failures is the nonfulfillment of the eligibility criteria, followed by patient-related reasons such as unavailability of a place to stay at the trial location. Broadening the eligibility criteria to better reflect the patients most commonly seen in the clinic will function both to decrease the rate of screen failures and increase the applicability of the study results.
Management of triple-negative breast cancer in the era of novel therapies
Authors: Sharma Rakesh Kumar , Gogia Ajay
Published: January 2022

The evolution of therapeutics for triple-negative-breast cancer (TNBC) has been lagging behind in comparison to that of other breast cancer subtypes. This review focuses on the recent developments with the potential to change future clinical practice. We searched the PubMed database for randomized trials on TNBC published in the past 2 years using the key term, “Triple-negative breast cancer.” Abstracts and outcomes of various studies presented at major oncology meetings were also assessed. A total of 54 studies were included in this review. Recent advances in molecular studies have delineated several cellular alterations revealing various targetable biomarkers. In addition, immunotherapeutic agents are being explored in the neoadjuvant setting and have shown major improvements in pathological complete response. Poly-adenosine diphosphate ribose polymerase inhibitors (PARPi) have transformed the management of TNBC, especially breast cancer gene-1/2 (BRCA1/2)-mutant and homologous recombination repair-deficient tumors. PARPi are now being utilized in the neoadjuvant setting, for maintenance following definitive treatment, and in metastatic disease. Sacituzumab govitecan has demonstrated improved outcomes in relapsed/refractory metastatic TNBC and has been approved for this indication. Capivasertib and ipatasertib have demonstrated promising results in patients harboring alterations in the phosphatidylinositol-3-kinase (PI3K)/protein kinase B pathway.
Umbilical Cord with Two Umbilical Veins
Authors: Gondi Bhoojata , Laxman S , Rao Paturi Venkata Rama , Maram Krishna Prasad
Published: January 2022

Umbilical cord with two umbilical veins is a rarely reported anomaly. Four-vessel cord is known to be associated with other congenital anomalies. Second umbilical vein is usually due to persistence of right umbilical vein. We report two cases of two umbilical veins; one newborn with four-vessel umbilical cord with two umbilical veins, who presented with severe pulmonary arterial hypertension, and another newborn with three-vessel umbilical cord with two umbilical veins, diagnosed to have transposition of great arteries. The presence of two umbilical veins mandates comprehensive workup to rule out other congenital anomalies. However, as highlighted by our first case, the presence of two umbilical veins is not always an ominous sign but could be seen in otherwise normal baby.
Respiratory Patterns in Neonates Hospitalized with Brief Resolved Unexplained Events
Authors: Kadivar Maliheh , Sangsari Razieh , Saeedi Maryam , Mirnia Kayvan , Kaveh Mahbod , Maleki Mohammad R , Makuku Rangarirai
Published: January 2022

Objective:

The objective of this study is aimed at investigating and evaluating respiratory patterns between infants hospitalized with brief resolved unexplained event (BRUE) and the control group.

Methods:

A convenient sampling method was used to select 52 patients presented at an urban, tertiary, and teaching pediatric hospital fitting the American Academy of Pediatrics' criteria of a lower-risk BRUE from December 2019 to December 2020. A random probability sampling method was used to select 52 patients as a control group. A NINIX apnea monitoring device was used to record respiratory time patterns and analyzed with SPSS 25.

Results:

A total of 104 participants participated in the study. Our study found that inspiration time (0.31 ± 0.04), expiratory time (0.93 ± 0.14), respiratory rate (38.48 ± 4.38), body temperature (37.11 ± 0.20), and heart rate (137.90 ± 6.60) were not statistically different between both groups. Mean birth weight in the control group and BRUE were respectively (3.43 ± 0.39, 3.23 ± 0.35). Mean gestational age in the control and BRUE groups were respectively (38.94 ± 1.01, 39.0 ± 1.04). Mean postnatal age in the control and BRUE groups were respectively (17.19 ± 6.07, 17.32 ± 7.35). Birth weight (P = 0.08) was statistically significant between both groups. In one patient, we recorded breath arrest for more than 20 s.

Conclusion:

There were no significant differences in respiratory patterns between infants hospitalized with BRUE and the control group. Low birth weight and low APGAR score are possible risk factors for infants experiencing BRUE, and more investigations are required to establish underlying causes.
Modification of book-binding technique during totally laparoscopic distal gastrectomy with Billroth I reconstruction
Authors: Waki Yuhei , Masayoshi Obatake , Sato Koichi , Yagi Shigehiko
Published: January 2022

The book-binding technique (BBT) has been developed to minimise extra detachment and mobilisation of the duodenum for totally laparoscopic distal gastrectomy (TLDG) with Billroth I reconstruction. Because of the cost-effectiveness and maximisation of the anastomotic lumen, we have modified the BBT in collaboration with the laparoscopic hand-sewing technique. Herein, we introduce a modified BBT (MBBT) and discuss its outcomes. The MBBT was performed using laparoscopic hand-sewing techniques with an absorbable barbed suture instead of using linear staples to close the defect of the anterior wall of the anastomosis site. The data of 163 patients with gastric cancer who underwent TLDG with Billroth I reconstruction performed with MBBT were retrospectively collected between April 2014 and December 2019. The mean anastomosis time was 25 min (interquartile range, 21 − 30). Postoperative complications of Clavien-Dindo grade II or greater occurred in 20 of the 163 patients (12.3%). Anastomotic leakage occurred in three patients (1.8%), whereas anastomotic stenosis occurred in one patient (0.6%). The cumulative incidence rate of anastomotic stenosis that required endoscopic dilation at 1 year was 1.2%. The MBBT method may be safe, practical, cost-effective and results in reduced staple use and anastomotic time.
Endoscopic retrograde cholangiopancreaticography-related complications – Experience from tertiary care teaching centre over half a decade
Authors: Dahale Amol Sonyabapu , Gupta Manish , Saxena Pritul , Kumar Ajay , Sonika Ujjwal , Kumar Manish , Srivastava Siddharth , Sachdeva Sanjeev , Sharma Barjesh Chander , Puri Amarender Singh , Dalal Ashok
Published: January 2022

Introduction:

Endoscopic retrograde cholangiopancreaticography (ERCP) is an essential therapeutic procedure with a significant risk of complications. Data regarding the complications and predictors of adverse outcomes such as mortality are scarce, especially from India and Asia. We aimed to look at the incidence and outcome of complications in ERCP patients.

Materials and Methods:

This study is a retrospective analysis of prospectively collected data of all the patients who underwent ERCP and had a complication from January 2012 to December 2018. Data were recorded in predesigned pro forma. The data analysis was done by appropriate statistical tests.

RESULTS:

A total of 17,163 ERCP were done. A total of 570 patients (3.3%) had complications; perforation (n = 275, 1.6%) was most common followed by pancreatitis (n = 177, 1.03%) and bleeding (n = 60, 0.35%). The majorities of perforations were managed conservatively (n = 205, 74.5%), and 53 (19%) required surgery. Overall, 69 (0.4%) patients died. Of these, 30 (10.9%) patients died with perforation. Age (odds ratio [OR]: 1.04, 95% confidence interval [CI]: 1.005–1.07) and need of surgery (OR: 5.11, 95% CI: 1.66–15.77) were the predictors of mortality in patients with perforation. The majority pancreatitis were mild (n = 125, 70.6%) and overall mortality was 5.6% (n = 10).

Conclusion:

ERCP complications have been remained static over the years, with perforation and pancreatitis contributing the most. Most perforations can be managed conservatively with good clinical outcomes.
How short or long should be a questionnaire for any research? Researchers dilemma in deciding the appropriate questionnaire length
Authors: Sharma Hunny
Published: January 2022

A questionnaire plays a pivotal role in various surveys. Within the realm of biomedical research, questionnaires serve a role in epidemiological surveys and mental health surveys and to obtain information about knowledge, attitude, and practice (KAP) on various topics of interest. Questionnaire in border perspective can be of different types like self-administered or professionally administered and according to the mode of delivery paper-based or electronic media–based. Various studies have been conducted to assess the appropriateness of a questionnaire in a particular field and methods to translate and validate them. But very little is known regarding the appropriate length and number of questions in a questionnaire and what role it has in data quality, reliability, and response rates. Hence, this narrative review is to explore the critical issue of appropriate length and number of questions in a questionnaire while questionnaire designing.
Management of refractory hypoxemia during elective extracorporeal support for complex tracheal resection
Authors: Venkataramani Ranjani , Lewis Alexander E. , Perez-Munoz Ivette , Gerstein Neal S.
Published: January 2022

Venovenous extracorporeal membrane oxygenation (VV-ECMO) is increasingly used in managing challenging airway and thoracic cases with complex airway manipulations. We present a case of a complex tracheal resection needing prolonged apnea times for which VV-ECMO was electively planned. Intraoperatively, the team was faced with continued oxygen desaturations during periods of apnea. With an algorithmic approach to troubleshooting hypoxemia, several factors were taken into consideration. Apneic oxygenation was applied to the open tracheal segment. Despite an open airway, the applied apneic oxygenation facilitated oxygenation to the portion of the cardiac output that was being shunted through the lungs as opposed to the VV-ECMO circuit, enabling uninterrupted completion of the surgical resection and reanastomosis.
Cardiovascular monitoring in patients with hypertrophic obstructive cardiomyopathy in a prone position
Authors: Koyama Yukihide , Asami Yu , Nishikawa Haruko , Ikezaki Hiroyuki , Tsuzaki Koichi
Published: January 2022

Supine positioning in patients with hypertrophic obstructive cardiomyopathy (HOCM) can affect their preload, afterload, and heart rate, potentially leading to cardiovascular collapse. Here, we report the successful anesthetic management of two patients with HOCM who underwent spinal surgery in a prone position. The approximate values of the systemic vascular resistance index (SVRI) were continuously calculated without measuring the central venous pressure. Intraoperative monitoring of the SVRI estimates may be helpful in patients with HOCM so as to avoid cardiovascular collapse when monitoring with both transesophageal echocardiography and a central venous catheter is clinically inappropriate.
Incidence of postoperative delirium in patients with preoperative and postoperative Obstructive Sleep Apnea Syndrome. A Systematic Review of the literature
Authors: Dooijeweerd S. , Torensma Bart , Faraj D. , Eldawlatly A.A.
Published: January 2022

Introduction:

Clinical research has suggested that there might be a correlation between postoperative delirium (POD) and obstructive sleep apnea (OSA) syndrome. We aimed to assess the association between POD and OSA syndrome.

Methods:

The electronic database PubMed was searched using combinations of terms for “Delirium,'’ “Obstructive Sleep Apnea,'’ and “postoperative delirium.'’ Excluded were studies without comparison as well as cross-sectional studies, case series, and case reports. The search was conducted with restriction toward English or not to the date of publication.

Results:

We included four studies in this review. In two of those studies, an association was found between POD and OSA syndrome. Pooled analysis showed a significant correlation between the two.

Conclusion:

High-quality studies regarding the subject are rare and heterogeneous. However, despite the lack of high-quality studies regarding the subject, the ones that are performed well conclude that there is a correlation between POD and OSA syndrome. Future studies addressing the matter should be well set up controlled clinical trials to draw conclusions and be able to investigate modifiable factors that can be used in a standardized protocol.
Prevalence of Psychological Symptoms in Patients Undergoing Pancreatoduodenectomy and Results of a Distress Management System: A Clinic-Based Study
Authors: Kang Mee Joo , Yu Eun-Seung , Kang Young Hwa , Park Hyeong Min , Park Sang-Jae , Kim Sun-Whe , Kim Jong-Heun , Han Sung-Sik
Published: January 2022

PurposePatients undergoing pancreatoduodenectomy are a high-risk group that requires psychosocial support. This study retrospectively reviewed the prevalence of psychological symptoms in patients undergoing pancreatoduodenectomy for periampullary neoplasm and the psychosocial referral rate after implementing full screening and triage algorithm for administering a distress management protocol based on the integrated supportive care system established in 2010.Materials and MethodsFrom September 2010 to December 2018, insomnia, anxiety, and depression were screened on the first day of admission (T1) and on the 10th postoperative day (T2). Patients with clinical levels of distress were referred to a mental health clinic for appropriate aftercare. ResultsThe adherence rate to routine screening was 82.7% (364/440). Among the 364 patients, the prevalence of insomnia, anxiety, and depression increased from 22.0% (T1) to 32.6% (T2, p=0.001), 29.1% to 33.6% (p=0.256), and 18.4% to 27.6% (p=0.001), respectively. Less than 45% of those with psychological symptoms expressed their needs for psychological supportive care. Among those with psychological symptoms at T2, clinical insomnia, anxiety, and depression were detected via in-depth evaluations among 77.2%, 38.1%, and 82.5% of patients, respectively. Patients who had two or more symptoms at T2 had a longer postoperative hospital stay, as compared to those with one or no symptoms (a median of 20.5 days vs. 18.0 days, p=0.006). Psychiatric consultation rate was 72.8% among patients with clinical psychological symptoms, and 74% of the consulted patients completed psychiatric intervention before discharge.ConclusionOver one-third of the patients had psychological symptoms before and after pancreatoduodenectomy. Implementing a routine psychological symptoms screening with a systematic psychiatric referral protocol enhanced surgeons’ responsiveness to patients’ psychological symptoms.
Defining and Valuing the Relationship Pattern of Actors’ Involvement on Cattle Farming Systems using Stakeholder Network Analysis in West New Guinea, Indonesia
Authors: Iyai Deny Anjelus , Mulyadi Mulyadi , Wajo Muhammad Jen , Naibey Rosdiana , Hayati Dwi Nur , Noviyanti Noviyanti , Bajari Makarius , Koibur Johan , Syufi Yafed , Pakage Stepanus , Inriani Noveling , Nuhuyanan Lamberthus E. , Purba Jublyana , Rahayu Bernadetha W.I. , Fatem Hendrik , Widayati Isti
Published: January 2022

Abstrak

Sapi merupakan salah satu peternakan prioritas utama di Indonesia. Ternak sapi telah memainkan peran penting dalam aspek ekonomi dari total pendapatan. Sebagai peternakan prioritas karena berbagai keterlibatan dan peran pemangku kepentingan. Studi dilakukan di Manokwari pada bulan April-Juni 2019 dengan menggunakan focus group discussion terhadap dua puluh individu, kelompok dan lembaga massa yang diwakili. Pertanyaan yang dibahas mengenai latar belakang, pengiriman sumber daya, interkonektivitas antar aktor, intervensi dan inovasi. Temuan utama adalah bahwa aktor yang dikelompokkan mendominasi, diikuti oleh aktor hukum, lembaga swasta, peran pemangku kepentingan dan memiliki efek positif karena kepentingan. Namun, ancaman eksis baik secara langsung tetapi tanpa efek balik. Tiga sumber daya bersama teratas adalah akses, kepuasan, dan waktu yang dihabiskan. Aktor dapat memiliki program jangka panjang dengan keberlanjutan menggunakan sumber daya netral hingga kuat. Hubungan aktor ditemukan dalam tiga kelompok, yaitu positif, negatif dan tidak ada hubungan. Intervensi sangat dibutuhkan, yaitu waktu yang dihabiskan, kepuasan, kebijakan, pengetahuan dan akses. Prioritas inovasi akan keterampilan, kebijakan, dan pengetahuan.

Kata kunci: Analisis jaringan pemangku kepentingan; Intervensi dan inovasi; Pelaku; Sumber daya bersama; Usaha peternakan sapi.  .

 

Abstract

Cattle is one of the top priority animal agriculture in Indonesia. It has played significant roles in economical aspect of Total revenues. Those are due to stakeholders’ involvement. Study was done in Manokwari from April to June 2019 by using focus group discussion towards twenty various represented individuals, groups and mass institutions. The queries discussed concerning background, resources delivery, interconnectivity amongst actors, intervention and innovation. The primarily finding is that grouped actors dominated, followed by laws actors, private types institutions, stakeholder role and having positive effect due to importance. However, threat existed directly without turn-back effect. The three top shared resources were access, satisfaction, and time spent. Actors can have long term period program with sustainability using neutral to strong power resource. Relationship of actors found in three groups, i.e. positive, negative and no relationship. Intervention was urgently needed, i.e. time spent, satisfaction, policy, knowledge and access. Priority of innovation will be skills, policy, and knowledge.

Keywords: Actors; Cattle farming business; Intervention and innovation; Shared resources; Stakeholder network analysis.
Studi Kasus: Kejadian Bruselosis Pada Sapi Potong Di Kabupaten Barru Provinsi Sulawesi Selatan Tahun 2015-2017
Authors: Pisestyani Herwin , Fitria Nisa Nurul , Wicaksono Ardilasunu
Published: January 2022

Abstract

There is still lack of bruselosis in beef cattle in Barru District, South Sulawesi. The aim of this study was to analyze data about the temporary distribution of disease by measuring spreading speed, and spatial distribution by mapping risk areas for bruselosis over the past three years. The data of this study was collected using the records from Dinas Peternakan and conducting interviews using structured questionnaires. This research was a descriptive study by measuring the incidence rate and describing the risk map using geographic information system (GIS). The results of this study indicate that, based on the incidence rate, the average of distribution rate of bruselosis in beef cattle in Barru is 5 cases per 10 000 heads/year. This incidence rate always decreases every year. There was no sub-district that classified as high risk. There was one area that classified as medium risk namely sub-district of Mallusetasi. Control measure that have been carried out by goverment were successful to reduce the spread of disease.

Keywords: Beef cattle; Bruselosis; Incidence rate; Occurrence; Risk.

 

Abstrak

Informasi mengenai penyebaran kejadian penyakit pada sapi potong di Kabupaten Barru Sulawesi selatan masih kurang. Penelitian ini bertujuan menganalisis data distribusi kejadian penyakit secara temporal dengan mengukur kecapatan penyebaran, dan secara spasial dengan memetakan wilayah berisiko bruselosis selama tiga tahun terakhir. Data dalam penelitian ini menggunakan rekapan dari Dinas Peternakan dan wawancara mendalam menggunakan kuesioner terstruktur. Penelitian ini mengunakan metode deskriptif dengan mengukur incidence rate dan menggambarkan peta risiko menggunakan geographic information system. Hasil penelitian ini menunjukkan bahwa berdasarkan incidence rate, kecepatan rata-rata penyebaran bruselosis pada sapi potong di Kabupaten Barru sebesar 5 kasus per 10 000 ekor/tahun. Nilai incidence rate tersebut selalu menurun setiap tahunnya. Kejadian penyakit paling tinggi terjadi di Kecamatan Mallusetasi dengan incidence rate sebesar 35 kasus per 10 000 ekor/tahun. Terdapat satu wilayah yang tergolong ke dalam risiko sedang, yaitu Kecamatan Mallusetasi. Tindakan pengendalian yang telah dilakukan oleh pemerintah setempat dikatakan berhasil dalam menekan tingkat kejadian penyakit.

Kata kunci: Bruselosis; Incidence rate; Risiko; Sapi potong; Tingkat kejadian
Deskripsi Daging Rana Arfaki (Anura; Ranidae) yang Dikonsumsi Masyarakat Moiley di Pegunungan Arfak
Authors: Pattiselanno Freddy , Athabu Anita Oce , Seseray Daniel Yohanes
Published: January 2022

Abstract

In Papua, especially in the Arfak Mountains, one of wild animals that commonly used as a non-animal protein source is frogs. Although it has been consumed by local people for generations, there is no representative information on the characteristics of Arfak frog meat. This study aims to determine the body weight and weight of carcass of Arfak frogs (Rana arfaki) comsumed by the Moiley communtiies in the Arfak Mountains. In addition, this study also attempts to reveal the physical quality and processing techniques of consumed Arfak forg meat. We used descriptive method with observation techniques in the field. The results show that an average body weight of Arfak frogs consumed in Mbenti is 2.53 ± 0.81gr, with an average of carcass percentage 46.77% and non-carcass percentage 53.23%.  The physical quality of the meat is, fresh and looks intact, the color of flesh and muscles is white to yellowish white, has a distinctive aroma, and elastic texture as well as strong muscles. The pH value of fresh meat is an average of 7.03. Various meat processing techniques are practiced including fried, stir-fry, grilled and smoked, and pickling/smoked is more preffered bacuse it is easy and the meat can keep longer as a source of food for household animal protein.

Keywords: Arfak; Cosnsumption; Meat; Quality; Rana arfaki

 

Abstrak

Di Papua khususnya di Pegunungan Arfak, salah satu jenis satwa yang dimanfaatkan masyarakat sebagai sumber protein hewani non-ternak adalah katak. Meskipun telah dikonsumsi oleh masyarakat lokal secara turun temurun, sampai saat ini belum tersedia informasi yang representatif tentang karakteristik daging katak Arfak. Tujuan dari penelitian ini adalah untuk mengetahui bobot badan dan berat karkas katak Arfak (Rana arfaki) yang dikonsumsi masyarakar Moiley di Pegunungan Arfak.  Selain itu juga penelitian ini bertujuan untuk mengetahui kualitas fisik dan teknik pengolahan daging katak Arfak yang dikonsumsi. Metode yang digunakan adalah metode deskriptif dengan teknik observasi atau pengamatan langsung di lapangan.  Rataan bobot badan katak Arfak (Rana arfaki) yang dikonsumsi oleh masyarakat di Mbenti yaitu 2,53 ± 0,81gr dengan rataan persentase karkas yaitu 46,77% dan persentase non-karkasnya sebesar 53,23%. Kualitas fisik daging katak Arfak yaitu memiliki karakteristik segar dan tampak utuh, warna daging dan otot putih hingga putih kekuningan, memiliki aroma khas, dengan tekstur elastis serta memiliki otot kuat. Sedangkan nilai pH daging katak Arfak segar yang dikonsumsi oleh masyarakat yaitu rata-rata adalah 7,03.  Teknik pengolahan daging yang dilakukan oleh masyarakat beragam antara lain goreng, tumis, bakar dan asap. Cara asar/asap lebih disenangi karena mudah dilakukan dan dapat memperpanjang masa simpan daging sebagai cadangan sumber pangan protein hewani rumah tangga.

Kata kunci: Arfak; Daging; Konsumsi; Kualitas; Rana arfaki
Crisis y transformación del sistema de partidos en España. Una aproximación generacional (2011-2018)
Authors: IMÍZCOZ Javier
Published: January 2022

Este trabajo aborda la crisis y la transformación del sistema de partidos en España durante la segunda década del siglo XXI desde una perspectiva generacional. Se consagrará al estudio de la evolución de la participación electoral de la juventud española durante la crisis política del país, entendiendo por « juventud » a aquellos integrantes de la generación nacida durante los Gobiernos de Felipe González (1982-1996). Estrechamente ligado a este seguimiento, analizaremos la forma en que la transformación de los hábitos electorales de esta generación en relación con las de los anteriores, marcada por su apuesta mayoritaria por opciones de regeneración, repercutió en el aceleramiento de la renovación generacional de la clase política española, actualmente una de las más jóvenes de Europa.
Le Natif Relatif, d'Eduardo VIVEIROS DE CASTRO
Authors: VIVEIROS DE CASTRO Eduardo , MORENO FREITAS Juan
Published: January 2022

Cet article tente de dégager les implications théoriques du fait que l’anthropologie n’étudie pas que des relations, mais que la connaissance qu’elle produit est, elle-même, une relation. On propose, alors, une image de l’activité anthropologique étant fondée sur la prémisse que les procédures caractéristiques de la discipline sont conceptuellement du même ordre que les procédures sur lesquelles on enquête. Parmi ces implications figure le rejet de la notion contemporaine selon laquelle chaque culture ou société incarne une solution spécifique à un problème générique, remplissant une forme universelle (le concept anthropologique) avec un contenu particulier (les conceptions natives). Bien au contraire, l’image proposée ici suggère que les problèmes sont eux-mêmes radicalement différents les uns des autres, et que l’anthropologue ne les connaît pas au préalable.
S’alimenter dans l’Espagne du XVIIe siècle d’après le Tesoro de las dos lenguas española y francesa de César Oudin (éd. princeps : 1607)
Authors: ZUILI Marc
Published: January 2022

C’est en 1607 que César Oudin, l’un des premiers hispanistes français, a publié un dictionnaire bilingue bidirectionnel pour l’espagnol et le français, le Tesoro de las dos lenguas española y francesa / Tresor des deux langues françoise et espagnolle. Cet ouvrage connut un grand succès et donna lieu à de nombreuses éditions successives, la dernière étant celle de 1675. L’étude que nous proposons porte sur les entrées de la partie « espagnol-français » de ce dictionnaire qui sont consacrées aux habitudes alimentaires des Espagnols du XVIIe siècle. En les regroupant judicieusement, nous espérons être parvenu à montrer comment César Oudin a su nous transmettre un tableau exact et très complet des us et coutumes alimentaires pratiqués alors dans ce pays.
Modelo de filas para análise de redes de múltiplos saltos
Authors: César Cecília de Azevedo Castro , De Carvalho Solon Venâncio
Published: January 2022

Neste artigo é apresentado um Modelo Analítico de Filas para auxiliar na decisão de quais dados, em uma malha de distribuição, um nó deve priorizar no atendimento: dados vindos de nós vizinhos, ou dados gerados localmente. Esta decisão visa melhorar a vazão da rede como um todo e diminuir o atraso. O projeto de uma Rede de Computadores sem Fio em Malha é uma possível aplicação deste modelo, pois sua topologia envolve o encaminhamento de pacotes de dados passando por diversos nós intermediários situados entre a origem e o destino. A análise de desempenho oferecida pelo modelo pode auxiliar o projeto da rede em relação à topologia, à carga submetida e aos serviços a serem implantados. Propõe-se também um critério de equidade que minimize o prejuízo dos nós mais distantes sem, contudo, prejudicar a vazão total. Os testes realizados indicam ganhos significativos na aplicação do critério de equidade.
Estructuras y mecanismos mentales de los estudiantes en los conceptos de permutación y combinación analizadas desde la teoría apõe
Authors: Veliz Joaquin Ignacio Cartes , Díaz Juan Patricio Soto , Bravo José Manuel Valencia
Published: January 2022

Este trabajo presenta una investigación en el área de la didáctica de la matemática fundamentada mediante la teoría APOE (Acrónimo de Acción, Proceso, Objeto y Esquema) formalizada en Asiala et al. (1996), la que permite analizar la forma en que los estudiantes construyen mentalemente cualquier concepto matemático, clasificando dichas construcciones en estructuras y mecanismos mentales. Se trabajó específicamente con los conceptos de permutación y combinación que se encuentran presentes en el nivel de segundo medio del plan de estudio de matemática y son fundamentales para el cálculo de probabilidades. Para efectos de este análisis se presenta una hipótesis sobre cómo los estudiantes aprenden los conceptos, denominada “Descomposición Genética” (DG), la cual se refina mediante la aplicación de cuestionarios y entrevistas a estudiantes de diferentes niveles de enseñanza media y profesores de matemática en formación para determinar cómo construyen los conceptos de interés y sugerir a los profesores una secuencia de construcción de los conceptos de permutación y combinación por medio de la resolución de problemas.
Analisis Pengaruh Literasi Keuangan, Inklusi Keuangan, Dan Tingkat Pendidikan Terhadap Perilaku Keuangan Pelaku Umkm Kedai/Warung Makanan Di Desa Bahagia Kabupaten Bekasi
Authors: Andriyani Puput , Sulistyowati Ari
Published: January 2022

This study aims to determine the effect of financial literacy on financial behavior, the effect of financial inclusion on financial behavior, and the effect of education level on financial behavior. The method in data processing used in this research is to use PLS (Partial Least Square) with the object of research being SMEs in the food stalls/shops in the Bahagia Village, Bekasi Regency. The sampling technique used was purposive probability with the form of non-probability sampling. The data collection technique used a questionnaire as many as 106 SMEs in the food stalls/shops in the Bahagia Village, Bekasi Regency. The results of this study indicate that there is a significant influence of financial literacy on the financial behavior of SMEs in food stalls/food stalls in Bahagia Village with t statistics 2.618 greater than t table 1.659, and a significant value of financial inclusion on financial behavior with t statistics 2.462 greater than t table 1.659, as well as the significant value of education level on the financial behavior of SMEs in food stalls/shops in Bahagia Village with a t statistics of 2.689 which is greater than a t table of 1.659.
PENGARUH AUDIT MANAJEMEN SUMBER DAYA MANUSIA TERHADAP KINERJA KARYAWAN DI RUMAH SAKIT UMUM DAERAH KOTA BEKASI
Authors: Rachdiansyah Ilham , Tesmanto Joni
Published: January 2022

This study aims to analyze the effect of Human Resources Management Audit on Employee Performance in General Hospital Bekasi.This study is a causal-comparative research. This study population is the entire General Hospital Bekasi employees totaling 158 respondents. The selection of the sample using Cluster Random Sampling method. The number of samples was 80 respondents, derived from four divisions: medical division (8 respondents), paramedic (32 respondents), medical support (10 respondents), and general (30 respondents). The data used are primary data in the form of a questionnaire. Prior to the study, first conducted trials-test with the instrument validity-test and reliability-test involving 20 employees of a General Hospital Bekasi were not involved back at the time of the study. Analysis prerequisite- test including normality-test, linearity-test, multicolinearity-test, and heteroscedasticity-test. The hypothesis-test in this study using simple-regression analysis.The results of this study indicate the Human Resources Management Audit have a significant and positive influence on Employee Performance in General Hospital Bekasi indicated by r2 value of 0.518, the significant value smaller than level of significant (0.000 0.050) and the regression line equation is Y = 0.813 + 0.766X.
ANALISIS PENGARUH PROMOSI TERHADAP TINGKAT PENJUALAN PRODUK BESERTA PERAMALAN PENJUALANNYA
Authors: Sendianto Sendianto
Published: January 2022

Promosi mempunyai peranan penting dalam manajemen pemasaran guna meningkatkan hasil penjualan karena tanpa adanya promosi sangatlah sulit untuk dapat meyakinkan pembeli. Penjualan adalah penyajian secara lisan oleh perusahaan kepada satu atau beberapa calon pembeli dengan tujuan agar barang atau jasa yang ditawarkan dapat terjual. Adapun tujuan dari penelitian ini adalah untuk mengetahui adakah Analisis Pengaruh Peomoasi terhadap Tingkat Penjualan Produk Beserta Peramalan Penjualannya Pada PT. Askotama Inti Nusantara.Teknik pengambilan sampel yang dipakai dalam penelitian ini penulis menggunakan teknik Random Sampling (Secara Acak pada Seluruh Konsumen) Dimana setiap anggota populasi mempunyai peluang yang sama untuk dipilih sebagai sampel menggunakan rumus Slovin yang dikutip Sevilla dalam Husein Umar (2012)Hasil penelitian diperoleh bahwa secara parsial dan simultan ada pengaruh yang positif dan signifikan antara Promosi Terhadap Tingkat Penjualan Produk Beserta Peramalan Penjualannya.
PENGARUH MOTIVASI KERJA DAN KEPEMIMPINAN TERHADAP KINERJA PEGAWAI PADA KANTOR KECAMATAN PUSAKAJAYA KABUPATEN SUBANG
Authors: Madiistriyatno Harries , Adiwijaya Toto Suharto
Published: January 2022

The success of an organization can not be separated from the quality leader, because a quality leader was able to utilize existing resources within the company, have the ability to direct the activities of subordinates that led, in anticipation of any changes that occur suddenly, it can correct any weaknesses No, could bring the organization to the agreed goals within a predetermined time. Especially for government agencies, particularly in the health sector providing motivation to employees should be continued. This meant that attitude, loyalty and commitment to the Pusakajaya district office increases so that every job will be easier to be completed on time and on target  The problems in this study is whether the motivation and leadership significant effect on the performance of employees at Pusakajaya district office Subang? and whether the motivation and leadership partially significant effect on the performance of employees at Pusakajaya district office Subang? The sampling technique systematic method of proportionate stratified random sampling. Data analysis techniques multiple linear regression analysis  This research resulted in the conclusion that the motivation and leadership together a significant effect on the performance of employees at Pusakajaya district office Subang. These results can be seen from the F count of 30,650 with a significance level of 0.000, which is smaller than α (0.000 0.050). The influence of work motivation and leadership to employees performance of 50.5% while the remaining 49.5% is influenced by other variables outside of this study. Motivation, and leadership is partially significant effect on the performance of employees at Pusakajaya district office Subang. These results can be seen from the t work motivation of 6.272 with a significance level of 0.006 which is smaller than α (0.000 0.050) and the t variable leadership of 5.906 with a significance level of 0.000, which is smaller than α (0.000 0.050).
PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN PELANGGAN PADA FBM WORLDWIDE
Authors: Azhari Munir
Published: January 2022

The effect of service quality on customer satisfaction in FBM WORLDWIDE. The study aims to determine service quality to customer satisfaction correlation and influence score at FBM WORLDWIDE. The method used is a survey method by using questionnaires to respondents as many as 75 respondents from customers/users of FBM WORLDWIDE delivery services. The data used are descriptive analysis, simple linear regression analysis, R test, T-test, and hypothesis testing. The results show that the service quality variable simultaneously had a positive and significant effect on customer satisfaction. The type of research is the quantitative method. Furthermore, Data collection techniques use carried out through survey methods. The number of samples is 75 people. The results of this study use statistical data methods with the SPSS (Statistical Package For Social Science) version 21 program. The results of the analysis state that the relationship between variable X (service quality) and variable Y (customer satisfaction) is forceful. It can be seen from the R-value of 0.903 so that it is close to 1. The influence of service quality variable (X) to customer satisfaction variable (Y) score is 0.813 or 81,3%. Furthermore,  the rest is influenced by other factors. The T-count value is 17.980 and T-table is 1.993 (based on the table), so T-count is greater than T-table which means Ha is accepted and Ho is rejected, meaning that the X variable (quality of service) is very related and has a significant effect on the Y variable (customer satisfaction).
MANFAAT KEBERADAAN SUMUR BOR TERHADAP USAHA MIKRO KECIL DAN MENENGAH (UMKM) IMPLIKASINYA PADA PEMBANGUNAN EKONOMI DI DUSUN SURUH
Authors: Widodo Widodo , Mulyana Dede
Published: January 2022

Melalui penelitian ini, penulis mempunyai tujuan umum dan tujuan khusus, yaitu sebagai berikut : Secara Umum, berkenaan dengan masalah yang diuraikan di atas, tujuan dari penelitian ini adalah Untuk mengetahui bagaimana manfaat keberadaan sumur bor terhadap Usaha Mikro Kecil Menengah (UMKM) dan Implikasinya terhadap Pembangunan Ekonomi di Dusun Suruh, Desa Hargomulyo, Kepanewonan Gedangsari, Kabupaten Gunungkidul. Secara Khusus, penelitian ini untuk memperoleh informasi mengenai kesejahteraan rakyat setelah terdapat Sumur Bor di  Dusun Suruh, Desa Hargomulyo, Kecamatan Gedangsari, Kabupaten Gunungkidul. Jenis dan rancangan penelitian dapat dikelompokkan sesuai tujuan penelitian, Penelitian ini tergolong penelitian deskriptif yaitu penelitian yang bersifat menjelaskan ssuatu yang terjadi pada objek. Berdasarkan hasil analisis tersebut ditemukan bahwa, dengan adanya Sumur Bor di Dusun Suruh sangat bermanfaat bagi UMKM serta  implikasinya pada pembangunan ekonomi karena Dusun Suruh merupakan dusun yang tandus dengan mengandalkan air hujan dan sering terjadi kekuarangan air ketika musim kemarau, sehingga baik tanah pertanian, perkebunan dan budidaya alam lainnya memerlukan pangairan yang dihasilkan dari Sumur Bor sebagai pangairan pengganti air hujan pada saat jatuhnya musim kemarau. Saran-saran yang dapat Penulis sampaikan terkait dengan hasil penelitian pada UMKM serta Implikasinya terhadap Ekonomi, yaitu: Dengan adanya Sumur Bor tersebut maka para pelaku UMKM dapat memanfaatkan dengan sebaik-baiknya sehingga Sumur Bor yang telah disediakan oleh para investor dan donatur betul-betul dapat mengembangkan UMKM di Dusun Suruh maka ekonomi akan berkembang lebih bagus. Mudah-mudahan di Dusun Suruh semakin banyak Sumur Bor yang dibuat oleh investor atau pemrakarsa-pemrakarsa sehingga Dusun Suruh dapat terpenuhi pengairan dengan menggunakan Sumur Bor sehingga UMKM di dusun tersebut dapat meningkat dan maju maka Pembangunan Ekonomi akan lebih cepat tercapai.
Contribution of Best Practices to Promote Sustainable Urban Freight Transport
Authors: Assis Tassia Faria De , Abreu Victor Hugo Souza De , Carneiro Pedro José Pires , D’Agosto Marcio De Almeida
Published: January 2022

Urban logistics decision makers face serious challenges in trying to make urban freight transport (UFT) efficient and sustainable. Therefore, it is necessary to identify best practices (BPs) to promote improvements on activity levels, modal shifts to lower-carbon transport systems, lowering energy and intensity, and reducing fuel carbon intensity. This paper conducts an exhaustive literature review that seeks to identify that are directly applicable to BPs promoting sustainable UFT and that indicate the opportunities and challenges of urban logistics. The results indicate that, although BPs make sense for themselves, the most powerful effect occurs when two or more of them are used together, multiplying their strengths. Furthermore, there is an expressive participation of environmental and economic indicators (costs and service levels) to the detriment of social indicators, thus indicating a literary gap.
On Multiset Minimal Structure Topological Space
Authors: DAS Rakhal , DAS Suman , TRİPATHY Binod Chandra
Published: January 2022

In this article we established the concept of multi-continuity in minimal structure spaces (in short $\mathscr{M}$ space) and the notion of product minimal space in multiset topological space. Continuity between $\mathscr{M}$-space, generalized multiset topology and multiset ideal topological spaces. We have investigated some basic properties of $\mathscr{M}$â€“continuity in multiset topological space, such as composition of $\mathscr{M}$â€“continuous functions, product of $\mathscr{M}$â€“continuous functions in product multiset topological space etc.