bluuebunny/crossref_metadata_2025 huggingface dataset:
The Origin of the Eschatological Feast as a Wedding Banquet in the Synoptic Gospels: an Intertextual Study
Authors:   ,   Andrews University, Long Phillip
Published: April 2023

The Problem. The problem this dissertation seeks to address is the origins of the wedding banquet imagery in the teaching of Jesus. Frequently, scholars will state that the image of a wedding banquet was a common messianic image in the first century. However, other than Isa 25:6-8, sources for the image of a banquet for the messianic age in the Hebrew Bible are sparse. Yet the image of a banquet clearly appears in the Synoptic Gospels in both the actions of Jesus as well as his teaching. Because the metaphor of a wedding banquet is not found in the literature of the Second Temple Period, scholars frequently assume that this sort of language was created by the Gospel writers and that Jesus himself did not claim to be a bridegroom. Method. In this study I propose an intertextuality method which seeks to give full weight to the rhetorical value of anauthor's use of earlier texts or traditions. First, the reader must first "hear an echo" within the text. By this I mean one recognizes something in the words or deeds of Jesus that sounds like a text or tradition from the Hebrew Bible. Second, having heard the echo of an earlier text or tradition, one must then determine which texts and traditions may have been used by the author. Since allusions to tradition are not direct citations, a wide range of texts must be gathered with linguistic and thematic links to the later text. Third, these observations drawn from the Hebrew Bible and Second Temple Period literature must be applied to the texts in the Synoptic Gospels which contain banquet or wedding imagery. This third step can be used as a test of the authenticity of the sayings of Jesus. I propose a "criterion of tradition congruence": If it is shown that a saying of Jesus stands within well-known traditions from the Hebrew Bible, then that saying is more likely to be authentic. Conclusion. Jesus did indeed claim to be a bridegroom and his ministry was an anticipation of the eschatological banquet. While there is no single text in the Hebrew Bible or the literature of the Second Temple Period which states the "messiah is like a bridegroom," the elements for such a claim are present in several traditions found in this literature. Jesus created this unique image by clustering three traditions drawn from the Hebrew Bible and applying them to his ministry. First, the eschatological age is inaugurated by a banquet eaten in the presence of God (Isa 25:6-8). Second, the end of the exile is often described as a new Exodus and a new journey through the wilderness (Isa 40-55). Third, the relationship of God and his people is often described as a marriage (Hosea, Jer 2-4). Jesus claimed that his ministry was an on-going wedding celebration which signals the end of the Exile and the restoration of Israel to her position as the Lord's beloved wife. Jesus himself combined the tradition of an eschatological banquet with a marriage metaphor in order to describe the end of the Exile as a wedding banquet.
Neurostimulation as a Putative Method for the Treatment of Drug-resistant Epilepsy in Patient and Animal Models of Epilepsy
Authors:   Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran., Bakhtiarzadeh Fatemeh , Zare Meysam ,   Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran., Ghasemi Zahra ,   Lunenfeld-Tanenbaum Research Institute, Toronto, Canada., Dehghan Samaneh ,   Stem cell and Regenerative Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.,   Eye Research Center, The Five Senses Health Institute, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran., Sadeghin Azam ,   Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran., Taghi Joghataei Mohammad ,   Department of Anatomy and Neuroscience, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Ahmadirad Nooshin ,   Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Published: April 2023

A patient with epilepsy was shown to have neurobiological, psychological, cognitive, and social issues as a result of recurring seizures, which is regarded as a chronic brain disease. However, despite numerous drug treatments, approximately, 30%-40% of all patients are resistant to antiepileptic drugs. Therefore, newer therapeutic modalities are introduced into clinical practice which involve neurostimulation and direct stimulation of the brain. Hence, we review published literature on vagus nerve stimulation, trigeminal nerve stimulation, applying responsive stimulation systems, and deep brain stimulation (DBS) in animals and epileptic patient with an emphasis on drug-resistant epilepsy.
Emotional Artificial Intelligence as a Tool for Human-Machine Interaction
Authors: Mamina R. I. , Piraynen E. V.
Published: April 2023

Introduction. One of the trends of global importance is the artificial intelligence (AI) and its innovations. One of such innovations has become emotional artificial intelligence (emotional AI/AI), it is called a revolutionary technology that can identify human emotions, process them in a timely manner and react “properly”. Experts consider emotional AI as an instrument that provides emotionally-oriented human–machine communication. The article discusses the specifics of emotional AI, achievements, potential opportunities, development prospects.

Methodology and sources. The methodology of philosophical, socio-psychological, comparative and interdisciplinary approaches is used. The sources used in the article are: special literature of domestic and foreign authors (B. Goertzel, D. Goleman, R. Picard,

D.I. Dubrovsky, E.M. Proidakov) scientific research, publications and websites devoted to emotional artificial intelligence, and its features (Aliya Green Emotional artificial intelligence: changing the human world for the better).

Results and discussion. The relevance of the topic of emotional AI determined the need to refer to the concept of ”emotional intelligence” (EI) as the basic basis of emotional artificial intelligence, which allowed us to show the essential characteristics of human emotional intelligence, its difference from AI. Emotional artificial intelligence is an innovation of modern AI, its main actors are anthropomorphic robots, text, voice chatbots and video bots, which are already actively demonstrating to the public their knowledge and skills in the field of psychology of emotions, which are being improved within the framework of the current AI.

Conclusion. Currently, there is a gradual process of teaching emotional AI to interact with a person, and although these achievements are not great yet, EII is gradually developing in accordance with the challenges of new realities within the specifics of modern applied AI. However, in the digital age, human–machine and machine-to-human communication is an interconnected process that should be aimed at building both utilitarian–useful and partnership relations in the practices of their interaction, which meets the requirements of the era and leads to further progress of AI – to the creation of a new, common AI – “human AI the level” which is supposed to greatly expand the capabilities of a person and society as a whole.
The Values of Modern Female Manager in Social and Structural Relations of the Business Sphere
Authors: Gurenko E. S.
Published: April 2023

Introduction. This article discusses the values of a modern female manager in social and structural relations of the business sphere from the gender point of view. The author sets the task of comparing the value positions of a female and a male manager in terms of several indicators (financial independence, career ambitions and expectations, balance between work and family, education and self-development) to identify gender differences in their activities, including those that affect the success of the organization in general.

Methodology and sources. Using the methods of complex analysis, as well as data obtained in the course of a sociological survey that covered managers of various status in the employment of Russian and foreign companies of various forms of participation and different market segments, through the prism of values, the specifics of the labor status of a female manager in socio-structural relations in business area. A questionnaire on the value orientations of modern manager in business and their attitude towards success in professional life was developed for the study. Territorial scope: Russian Federation. Timeframe:  autumn  2019  –  January  2022.  The  sample  is  represented  according  to  “the employee level in organizational hierarchy” criteria. The study involved 130 participants.

Results and discussion. It was found that the value structure of women and men differs slightly, and those qualities that women possess by “their nature” could be “useful” in business. It was also found that family and children are no longer an obstacle to professional growth and development for a modern woman, allowing her to easily compete with men in various business segments, including management.

Conclusion. The author concludes that in modern conditions not only the value orientations of a woman have changed, but also her behavior in the social life. This is explained by the fact that values, in particular social ones, are the product of a woman's socialization, her assimilation of social, moral, aesthetic, and ethical ideals and the requirements placed on her as a member of society. The same is true of the basic values – their structure has changed and today expresses the fundamental, universal orientations and norms of human behavior dictated by modern realities – digitalization, the economic crisis, political instability, and the pandemic.
The study on the geopolitical conflicts and coexistence between France and Germany in the course of the EU-Expansion during the early 21st century : Centering around analyzing the geopolitical strategies on the European continent of both countries
Authors:   United European Research Society, Lim Taehun
Published: April 2023

This study consists to analyze the conflicts on the expansion of the EU in the early 21st century, through comparing the geopolitical interests of France and Germany. By doing this, this study aims to explore an alternative policy for the coexistence of the geopolitical interests of both countries in the course of the EU-Expansion. Concerning the EU-geopolitical construction, France prefers to consolidate the politico-economic integration of the existing Southern European member states to the EU. And she wants to expand the geopolitical sphere of influence of Europe toward the Mediterranean region. On the contrary, Germany supports the eastward expansion of the EU into Eastern Europe. And she seeks to make European geopolitical influences on Central Asia. This interest conflict between both countries has happened, because the geopolitical strategy of France is based on the Western European centrality and that of Germany has been developed by the Central European centrality. In order to minimize this geopolitical clash on the EU-Expansion between both countries, it would be necessary to develop and to implement constantly the European Neighborhood Policy, of which objective is to stabilize the neighboring regions of the EU and to increase the interdependence with them.
Environmental Cooperation as a Driver of ‘Low Politics’ in the Baltic Sea: An Actor-Based Analysis
Authors:   United European Research Society, Hwang Juneseo , Yu Hyunkyo
Published: April 2023

The geopolitical collision between the European Union (EU) and Russia is being heightened by the recent war between Russia and Ukraine. The former has financed Ukraine for self-defence and reinforced economic sanctions against Russia. In response, the latter has ceased energy exports to and increased the military strength in bordered areas with its European counterpart. As the war continues, the security tension intensified in the Black Sea diffuses to the Baltic Sea that the two great powers share. This research casted light on four types of organisations for ‘low politics’, which bridges Europe and Russia by addressing common agenda for the environment and public health. Those are intergovernmental organisations, city networks, civil society coalitions, and university networks. The study found that although these actors are not powerful enough to reshape the landscape of regional security politics, they contribute to confidence building in the long term and enhancing living standards through cross-border cooperation.
Substantiation of control of special physical preparedness of athletes aged 12–13 in taekwon-do ITF
Authors:   Vasyl Stefanyk Precarpathian National University, Danyshchuk Serhii , Yatsiv Yaroslav ,   Vasyl Stefanyk Precarpathian National University, Hnatchuk Yaroslav ,   Khmelnytskyi National University
Published: April 2023

Physical preparedness is a basic type of athletes’ preparedness in all versions of taekwon-do. Attention to physical preparation remains fixed and actual at various stages of multi-year sports improvement. Researchers and methodological papers mostly present specifics of training and competition activity in taekwon-do WTF and to a lesser extent taekwon-do ITF and GTF. This calls for specification of the set of information means for control of specialized physical preparedness of athletes aged 12–13. The aim of the paper is to substantiate parameters of control of specialized physical preparedness of athletes aged 12–13 in taekwon-do ITF. Materials and methods. The following methods have been used: the method of theoretical analysis and academic and methodological references data generalization; analysis of documented materials; the method of expert polling; methods of mathematical and statistical data processing. The structure and content of Training programs in taekwon-do ITF, WTF, rules of competitions in taekwon-do ITF have been studied. 24 coaches in taekwon-do ITF were involved in expert polling; presentation group of young athletes aged 12-14 (15 persons) whose training experience in taekwon-do ITF was over 5 years were additionally involved. The questions were related to determination of time spells priority for control of athletes’ special speed qualities; time spells for control of athletes’ special power endurance; kicks and punches as well as combination of two-three hits that can be used for control of athletes’ special physical preparedness. Polling results processing was done via ranking of the suggested variants by shares of respondents’ answers. Results.It has been revealed that when elaborating the program of testing of special physical preparedness of athletes aged 12–13 in taekwon-do ITF it is reasonable to rely on the use of actions in two modes: speed and power mode (acting for 10-30 seconds), and speed and power endurance (90–120 seconds). Execution of single punches in control of physical preparedness must include hand actions: jab, upper-cut or cross, and kicks: Dollyo Chagi, Yop Chagi, or Naeryo Chagi. Execution of combination of two hits, according to expert recommendations, should be done in: “Dollyo Chagi-cross” and “Yop Chagi-hook”, while combination of three hits – “hook-Dollyo Chagi-dwi chagi” and “jab – Yop Chagi-hook”. Conclusions. Parameters of control have been substantiated for the first time; use of single kicks and punches, execution of two and three hits for control of special physical preparedness of athletes aged 12–13 in taekwon-do ITF have been specified
Health influence of functional training on the organism of women of the second period of mature age
Authors:   Universitatea de Stat din Transnistria «Taras Şevcenko, Samoliuc Olga , Cheban Tatiana ,   Universitatea de Stat din Transnistria «Taras Şevcenko
Published: April 2023

Mature women are active consumers of various fitness industry services. The main goals of such classes are to obtain a healing effect, as well as physical improvement, expressed in the development of physical qualities, increasing efficiency and the ability to perform basic human movements. A variety of fitness areas also implies a difference in their effect on the body of those involved. Recently, functional training has become increasingly popular, during which exercises with a specific motor task are used.Research results. The purpose of the study is to study the impact of functional training on the health status of women of mature age. Research results. One-hour functional training in group classes for women of mature age (47-55 years old), used three times a week for one year, has a positive effect on the health of those involved: performance in functional exercises of a speed-strength and coordination character is significantly improved, as well as in flexibility exercises. Functional training also contributes to the adaptation of the cardiovascular system to physical activity. Conclusions. 1. An experiment involving 23 people showed that regular group training for one hour three times a week for one year, including functional exercises, improves the response of the cardiovascular system to physical activity in women of mature age 47-55 years old, leading a sedentary Lifestyle. 2. The use of functional exercises for an hour three times a week for one year contributes to the improvement of speed-strength indicators, coordination of movements, flexibility in women of mature age 47-55 years. 3. Effective functional training should include continuous exercises in a standing position, complex coordination exercises, strength exercises in a functional format. Classes should be conducted to music (no more than 132 beats / min). Classes should be of coordination complexity for those involved, and programs should be constantly updated
Assessment of physical condition indicators in senior men
Authors:   Ternopil Volodymyr Hnatiuk National Pedagogical University, Khoma Oleksandr
Published: April 2023

The relevance of the research topic. The paper presents the results of the assessment of physical condition indicators in 60-70-year-old men. The aim of the study was to identify the characteristics of physical condition indicators in senior men. Methods: theoretical analysis of special scientific and methodological literature, anthropometric and medical biological methods, and mathematical statistics. The study was conducted at the National University of Water and Environmental Engineering (Rivne, Ukraine). The ascertaining pedagogical experiment involved 50 senior men (with an average age of 65.06 ± 3.06 years). Results. Physical condition indicators characterizing physical development and functional status of the cardiorespiratory system were identified. Regressive changes at the morphological level were found: a trend to the increase in certain somatometric parameters and decrease in physiometric indicators of senior men. A significant decrease in the cardiorespiratory capacities of the studied subjects was revealed: 84 % of elderly men needed treatment to improve the functional state of the cardiovascular system. The majority (60 %) of respondents were diagnosed with high blood pressure. The obtained results also indicated decreased adaptation potential and increased tension of the regulatory systems. Satisfactory adaptation of the cardiovascular system was found in 8 %; tension of the adaptation mechanisms – in 20 %; unsatisfactory adaptation – in 40 %; and failure of adaptation – in 32 % of senior men. Conclusions. Based on the results of the study, the physical condition indicators of senior men were assessed. It was found that most of the indicators have certain deviations from the normal range, which should be taken into account when developing a comprehensive program based on the use of means of health-enhancing recreational physical activity.
Barrocos. Mímesis, legado y orfandad, ensayos de Santiago Cevallos
Authors: Torres Galo Alfredo
Published: April 2023

Barrocos. Mímesis, legado y orfandad, ensayos de Santiago Cevallos
Escritura y conciencia crítica: las crónicas modernistas de César E. Aroyo
Authors: Abad Ordóñez Gustavo
Published: April 2023

Este artículo presenta una inmersión en la narrativa de César E. Arroyo (Quito, 1886-Cádiz, 1937). Se analizan diez crónicas enviadas desde España por el escritor y diplomático ecuatoriano y publicadas en Quito por la revista Letras, entre 1912 y 1919. Arroyo deja ver en este conjunto de textos una profunda vocación humanista y una permanente actitud creativa respecto del lenguaje y sus posibilidades. Temas como la literatura, la guerra, el socialismo, la religión, el arte, la filosofía, entre otros, fluyen mediante diversos géneros, como la crónica, el perfil, el ensayo, la reseña crítica. En la mayoría de los casos, Arroyo logra una convivencia armónica entre ellos.
Ensaio filosófico sobre a natureza da expansão cósmica
Authors: Soares Francisco
Published: April 2023

O presente artigo tem como principal objetivo a busca por análises filosóficas integradas a um senso puramente matemático relacionadas com a expansão do Universo. Trata-se como indagação central a possibilidade de haver espaço fora do Universo. O panorama aplicado leva a uma série de constatações e problemas físicos, cuja exposição será realizada. A metodologia utilizada segue, cronologicamente, a ordem por uma análise filosófica do problema, com soluções do mesmo gênero, seguindo para uma análise científica. De início, serão abordadas questões teológicas integradas a um estudo geral da Filosofia Medieval e do Idealismo Alemão, enquanto a análise se aprofunda na abordagem do problema sob uma noção histórica. Por fim, serão expostas consequências do problema sob uma perspectiva científica. A conclusão é restrita a uma perspectiva filosófica abrangente: considera a expansão cósmica como fruto de um problema muito maior, que envolve a dinâmica da realidade, de modo que fica demonstrada a impossibilidade de compreendê-la apenas cientificamente, levando a cabo a relevância da reflexão como base metodológica de apoio, enquanto define, ainda, uma série de consequências sobre a possibilidade apresentada, estudando diversas possibilidades.
Dominação masculina e as práticas de enfermagem
Authors: Carneiro Shayanna Mickaela Duque , Silva Jéssica Íris Franco da , Silva Hallyson Leno Lucas da , Lima Maria Juraci de Oliveira , Menezes Rejane Maria Paiva de , Medeiros Soraya Maria de , Oliveira Jonas Sâmi Albuquerque de
Published: April 2023

Este estudo teve como objetivo refletir sobre a dominação masculina e os desafios de gênero na enfermagem nos dias atuais. Observa-se que o sistema patriarcal pode ser facilmente comparado ao capitalismo, pois em ambos existe como padrão uma classe explorada constituída por mulheres e a opressora composta por homens. Embora se tenha que considerar que, no sistema capitalista, parte da população masculina também seja explorada, há que se ressaltar que a exploração feminina tem matrizes diferenciadas. Os conflitos de relação de gênero estão presentes historicamente entre as atividades desenvolvidas pela enfermagem, composta predominantemente por mulheres, e as práticas médicas com domínio principalmente masculino. O cuidado, instrumento de trabalho da enfermagem, sempre foi associado ao sexo feminino e muitas vezes é confundido com as obrigações domésticas ou assistência à família. Merece destaque também o conservadorismo médico quanto à questão de mudanças nos serviços partindo das enfermeiras. Para eles, é inadmissível que uma mulher, um ser inferior, responsável apenas pela execução das atividades prescritas por eles, tenha a capacidade de realizar mudanças institucionais permitindo melhorias para o serviço e, consequentemente, para os clientes. As lutas feministas proporcionaram avanços em todo o mundo, mas no âmbito da saúde, quando nos referimos à enfermagem e à medicina, ainda é preciso avançar, pois na maioria das instituições de saúde predominam as organizações médicas de forma hierárquica e verticalizada, reservando para as enfermeiras lugares inferiores aos médicos. Ainda há um grande caminho a ser percorrido pela enfermagem, mas os autores acreditam que o reconhecimento da necessidade da mudança pode ser considerado como o recomeço.
Utilidad de la hemoperfusión con Polimixina B en la enfermedad pulmonar intersticial rápidamente progresiva asociada a anti-MDA5
Authors: Jiménez-de la Cruz Laura , Martínez-Díaz Laura , Calero-Paniagua Ismael
Published: April 2023

La dermatomiositis asociada a anticuerpos anti-MDA5 engloba diferentes fenotipos clínicos como son la vasculopatía cutánea, la afectación reumatológica y la enfermedad intersticial pulmonar rápidamente progresiva, la cual implica peor pronóstico. Esta afectación puede suponer un reto en la práctica clínica por la complejidad para llegar al diagnóstico y la refractariedad en los tratamientos.
Se recomienda iniciar una terapia combinada basada en glucocorticoides a altas dosis e inmunosupresores clásicos. En casos refractarios se han descrito otros tratamientos como la plasmaféresis, las inmunoglobulinas IV, tofacitinib o la hemoperfusión con Polimixina B.
Neumonitis lúpica: presentación de un caso
Authors: Serrano-Virlán Cinthia , Sevilla-Blanco Juan Antonio , Lobato-de la Sierra María del Pilar
Published: April 2023

El lupus eritematoso sistémico (LES) es una enfermedad autoinmune sistémica. Las manifestaciones pleuropulmonares se presentan casi en un 50% de los pacientes en el transcurso de la enfermedad. De todas las manifestaciones, la neumonitis lúpica aguda (NLA) es una complicación inusual, cuya presentación clínica se caracteriza por fiebre, disnea, pleuritis y tos con mínima expectoración. La base del tratamiento son los corticoesteroides sistémicos e inmunodepresores a dosis altas. El objetivo de este artículo es describir una complicación infrecuente y con elevada mortalidad en pacientes afectos de lupus eritematoso sistémico.
Coma en adulto joven de causa inhabitual
Authors: Aranda-Calleja María Ángeles , Paraíso-Cuevas Vicente , Morales-Conejo Montserrat , Castro-Fernández Bernardo Andy , Toldos-González Óscar
Published: April 2023

Actualmente disponemos de la prueba del talón en el recién nacido para despistaje de los principales errores congénitos del metabolismo entre otras patologías que incluyen el déficit de 3-hidroxi-3-metilglutaril-CoA (HMG-CoA) liasa. En este caso, la ausencia de un diagnóstico previo o de antecedentes familiares de esta enfermedad supuso un reto diagnóstico en un adulto joven con una presentación clínica grave. La colaboración de distintos especialistas y el estudio exhaustivo con diversas pruebas complementarias condujo al diagnóstico de la enfermedad por déficit de 3-hidroxi-3-metilglutaril-CoA (HMG-CoA) liasa.
Lo que el prurito esconde
Authors: Buforn-Pascual Amparo , Salvador-Marí Irene , Ramírez-Boscá Ana Adela , Ibarra-Vega Nataly Isabel , Maestre-Peiró Ana
Published: April 2023

El prurito es un síntoma frecuente pero inespecífico que puede presentarse en multitud de patologías. A través de este caso clínico veremos como este síntoma nos permite llegar al diagnóstico de una entidad hematológica rara y de mal pronóstico.
Pleuropericarditis aguda recidivante tras vacunación frente a SARS-CoV-2
Authors: Jara-Vidal Marina , García-de Oro Ángela
Published: April 2023

La pericarditis aguda consiste en la inflamación del pericardio. Suele cursar con dolor torácico asociado a cambios en el electrocardiograma y puede acompañarse de derrame pericárdico y roce pericárdico. La forma de presentación más frecuente es autolimitada, pero hasta un 30% de los casos presentan recurrencias. El tratamiento está basado en reposo y antiinflamatorios esteroideos. Esta patología constituye uno de los efectos adversos a tener en cuenta en la vacunación frente al SARS-CoV-2. Presentamos el caso de un varón de 68 años con pleuropericarditis aguda recidivante tras vacunación con Moderna.
Colecistitis aguda perforada con bacteriemia por Actinomyces naeslundii
Authors: Ropero-Luis Guillermo , Romero-Masa Estíbaliz , Plata-Ciézar Antonio , Ruiz-Mesa Juan Diego , Reguera-Iglesias José María
Published: April 2023

La infección de la vesícula biliar por bacterias del género Actinomyces es extremadamente rara, habiéndose descrito hasta la fecha 25 casos en la literatura. Presentamos el caso de un hombre de 68 años que ingresó por un cuadro de fiebre de corta evolución sin focalidad infecciosa aparente. Las pruebas complementarias revelaron la existencia de colecistitis aguda perforada junto con bacteriemia por A. naeslundii. El paciente realizó tratamiento antibiótico con amoxicilina-clavulanato durante 3 semanas, sensiblemente inferior a las pautas habituales. Posteriormente se sometió a una colecistectomía electiva. El estudio histopatológico de la pieza quirúrgica confirmó la resolución completa de la infección.
Infección sistémica por citomegalovirus en adolescente inmunocompetente
Authors: Rivas-Otero Diego , Carmona-González Julia , Suárez-Huelga Carmen , Pablo-Casas Manuel de
Published: April 2023

El citomegalovirus (CMV) es un virus ADN perteneciente a la familia Herpesviridae con capacidad de generar latencia en el organismo tras la primoinfección. La prevalencia del virus es de entre un 56% y un 94% de la población en función del área geográfica. Es responsable de múltiples cuadros clínicos en individuos inmunocomprometidos y complica frecuentemente los trasplantes de órganos. Sin embargo, es extremadamente infrecuente que cause cuadros clínicos graves en inmunocompetentes, y apenas hay unos pocos centenares de casos descritos en dicho grupo poblacional en las últimas décadas. Se presenta el caso de una adolescente de quince años que fue diagnosticada de colitis por citomegalovirus, padeciendo un cuadro clínico grave que requirió ingreso hospitalario durante dos semanas.
Ứng dụng nền tảng nhúng Beagleboard C4 trong điều khiển thiết bị bằng tiếng nói tiếng Việt
Authors: Kiên Đào Trung , Ngọc Yến Phạm Thị , Lan Hương Nguyễn Thị
Published: April 2023

In  this  paper,  a  device  control  system using  voice  recognition  developed  for  the  embedded platform Beagleboard C4 is introduced. The system is able  to  recognize  voice  commands  in  Vietnamese obtained  via  a  microphone,  then  realizes  the corresponding  control  tasks.  Two  applications  are taken  into  experiment  are  a  six-legged  spider-like robot,  and  a  fan.  The  whole  system  including  voice capturing,  voice  recognition,  and  device  control modules  are  developed  on  a  single  board,  which  is limited in size, resources as well as computing power.
Critical analysis of the definition «costs» in the accounting practice of agribusiness enterprises in the field of crop production
Authors: Demchuk Oleksandr
Published: April 2023

The scientific article summarizes and critically analyzes scientific approaches to the interpretation of the definition of «costs» at the macro level, as well as investigating the composition of crop production costs at agribusiness enterprises, in particular. The transformation of the definition of «costs» in a historical retrospective has been traced, and it is proved that the definition of «costs» acquired a scientific meaning only in the 17th century. It was found that in the course of the evolution of the definition «costs», two approaches to the interpretation of costs developed: the accounting one, based on factual costs, and the economic one, based on favorable opportunities. In addition to accounting costs, economic costs include alternative costs, which is a lost benefit from the alternative use of resources. It is substantiated that the content of accounting costs in crop production is expedient to be studied from the standpoint of both financial and managerial accounting. It is established that in the financial accounting of agricultural business enterprises, costs are considered in terms of their impact on the change in the value of property, and in managerial accounting – in terms of use of a certain amount of material, labor, financial, and other resources in the production process. The composition of crop production costs in terms of economic elements in financial accounting and in the context of calculation items in managerial accounting is covered. The influence of technological and agrobiological features of agricultural production (seasonality, dependence on natural and climatic conditions, uneven implementation of costs throughout the year, etc.) on the organization of cost accounting in crop production is considered. The expediency of including not only actually consumed resources but also estimated costs and lost profits in the management accounting of plant production costs is substantiated. The analysis of the definition of «costs» in the course of the conducted research has shown that for quite a long time there have been discussions about the feasibility of distinguishing between the definitions of «costs» and «expenses». We support L. V. Napadovska's proposal about the expediency of using the term «costs» in financial accounting, and the term «expenses» in management accounting.
Logistics in construction: decision-making methods, features and prospects development
Authors: Ivanov Yurii
Published: April 2023

The article examines the peculiarities of logistics in the construction industry. The prospects for the development of industry logistics are associated with the use of outsourcing in the supply of construction companies. Decisions on managing supply chains for construction materials are systematized, and decisions made by logistics providers and construction industry organizations are identified. The possibility of reducing the amount of costs in the activities of construction companies is proposed through the analysis of processes based on classical concepts and their transformation into logistic concepts of organization. Additionally, according to the concepts of key competencies and business process reengineering, it is proposed that companies establish the best source of competitive advantage by making key processes as efficient and cost-effective as possible, while non-key processes can be outsourced to gain additional competitive advantage. Businesses are interested in reducing inventory holding costs, as analysts confirm the fact that inventory storage costs companies at least 25% of their book value per year. The practice of applying logistics proves its effectiveness. In a number of works, data on the effectiveness of logistics have been published. In one of them it is noted that, according to experts (expert assessment), the use of logistics allows to reduce the level of stocks by 30–50%; reduce product movement time by 25–45%; reduce repeat warehouse transportation by 1.5–2.0 times; reduce costs for road transportation by 7–20%, and for rail transportation by up to 12%. Logistics, developing at enterprises of various branches of the economy, acquires specific branch features. In construction, it has a number of features, among which the rather low level of logistics as a branch of the national economy of Ukraine stands out. To optimize costs in the supply chain, it is recommended to consider various decisions made by both the construction company being serviced and the logistics provider. Specifically, the construction company is required to specify logistic service requirements that are determined by plans and schedules for construction work, specifications dictated by construction technology, as well as cost, time, and quality characteristics of the expected service.
Evaluation Framework for Social Impact on the E-Co-Housing Project in Budapest
Authors: Babos Annamária , Csizmady Adrienne , Orbán Annamária , Szabó Julianna
Published: April 2023

In Europe, today's affordable housing and co-housing projects represent complex products, complementing the physical intervention with economic and social techniques. This means that purely environmental and economical evaluation is not sufficient for these projects. While environmental and economical evaluation methodologies are widespread and advanced in the construction sector, methodologies to evaluate the social impacts of housing projects are rarely used and therefore underdeveloped.This study elaborates a framework to evaluate and monitor the social impacts of a complex social housing and co-housing project. The method adopted implements the Social Life Cycle Assessment, integrating a Post Occupancy Evaluation as the main tool for collecting and analysing data. The presented assessment framework is elaborated for the E-Co-Housing Model, a new experimental model so far as the development of affordable housing in Budapest is concerned. However, it delivers a starting point for more complex sustainability analysis of residential buildings in general.The guideline for the Evaluation Framework is the methodology of the Social Life Cycle Assessment of Products, clarifying and improving some of its usual elements. The study of the E-Co-Housing Model shows that housing products, especially affordable and co-housing projects significantly differ from other products. The differences are their main stakeholder groups, their life cycle stages and in their impact ways too. Therefore, housing products need a special S-LCA methodology to assess in a balanced way the complex aspects of its environmental, economic, and social sustainability.
Tendência predominante da mortalidade por leucemia na população infantojuvenil no nordeste brasileiro entre 2009-2019: estudo ecológico
Authors: Santos Anike Raelle Teixeira dos , Santos Ester Maria dos , Rodrigues Adalberto , Cavalcanti Maria Eduarda Pinto , Azevedo Breno , Figueirêdo Bárbara Bernardo
Published: April 2023

Introdução: A leucemia corresponde a uma doença hematológica com período de latência curto, desenvolvendo-se mais rapidamente. Gerando sérios impactos na saúde pública. Objetivo: Reunir dados acerca da tendência de mortalidade por leucemia na população infantojuvenil no nordeste brasileiro, entre os anos de 2009 a 2019. Metodologia: Estudo ecológico de período temporal de abordagem quantitativa. Foram coletados e incluídos os números de óbitos da população infanto-juvenil brasileira entre os anos de 2009 a 2019, com ênfase na região Nordeste. Os dados foram coletados entre março e abril de 2022 através do Atlas Online de mortalidade do Instituto Nacional do Câncer. As causas de morte analisadas foram a leucemia linfoide (C91), leucemia mieloide (C92), leucemia monocítica (C93), leucemias de células de tipo especificado (C94) e leucemia de tipo celular não especificado (C95). Resultados: Entre 2009 a 2019 no Nordeste, ocorreram 16.579 óbitos por causa da leucemia, destes, 3.010 foram na população infantojuvenil, com uma média anual de 273,63±19,601. Em relação à faixa etária, o grupo de 15 a 19 anos apresentou o maior número de mortalidade, com o valor total 776 óbitos. Os estados do Piauí, Rio Grande do Norte, Sergipe, Ceará e Alagoas apresentaram as quatro maiores taxas de mortalidade da região. Conclusão: Estudos que procurem identificar padrões, sejam eles integrativos, sistemáticos ou ecológicos são essenciais não apenas para verificar qual a parcela da população que está sendo mais acometida pela doença, mas também para conhecer quais pontos ainda necessitam de atenção por parte das políticas pública.
Aumentando a performance do Firebird: estratégias e boas práticas
Authors: Souza Alice Silva de , Carr Caroline Nunes , Oliveira Deivid Cesar Costa de , Silva Felipe Grotto da , Sousa Lorena Dalva da Conceição , Carr Renato Ferreira
Published: April 2023

Este artigo tem como objetivo analisar e otimizar a performance do Firebird, um sistema gerenciador de banco de dados open source, aplicando a metodologia de estudo de caso em contextos empresariais variados para identificar estratégias eficazes de aprimoramento, como o uso adequado de índices (incluindo compostos), a implementação de cache, realização de transações rápidas com planejamento e acompanhamento, e o emprego correto de parâmetros nas consultas. A pesquisa destaca a importância do planejamento na criação de índices e a necessidade de conhecimento profundo da arquitetura do Firebird e técnicas de programação adequadas. Além disso, a análise também enfatiza a relevância da colaboração entre desenvolvedores e administradores de banco de dados para garantir um desempenho otimizado. Ao aplicar as estratégias identificadas, os resultados demonstram que, com planejamento cuidadoso e ajustes precisos, é possível melhorar a performance do Firebird, tornando-o mais eficiente e rápido, fornecendo assim insights valiosos para sua aplicação em diferentes cenários empresariais e contribuindo para a tomada de decisões informadas.
THE RELATIONSHIP BETWEEN UNIVERSITY STUDENTS’ E-HEALTH LITERACY AND HEALTHY LIFESTYLE BEHAVIORS
Authors: KASIMOĞLU Necla , KARAKURT Papatya , ATALIKOĞLU BAŞKAN Sebahat
Published: April 2023

This study aimed to analyze the effects of university students’ e-health literacy on their healthy lifestyle behaviors. This is a descriptive and cross-sectional study. It was conducted with 1,714 students in a university in the east of Turkey during the 2018-2019 academic year. The data were collected using Lifestyle Behaviors Scale II in face-to-face interviews. The participants’ mean e-Health Literacy Scale score was 27.80±6.12, and their mean Healthy Lifestyle Behaviors Scale II score was 125,74±19,09. These scores did not vary significantly by age, gender or residence. They did vary significantly by year of study and faculty. A positive significant relationship was found between the participants’ total e-Health Literacy Scale and Healthy Lifestyle Behaviors Scale II scores. The participants’ mean e-Health Literacy Scale score was above the moderate level, and their mean Healthy Lifestyle Behaviors Scale II score was at a moderate level. Higher mean e-health literacy correlated with higher mean healthy lifestyle behaviors.
Inflammation in obesity-driven osteoarthritis
Authors:   , Warmink Kelly
Published: April 2023

Osteoarthritis (OA) is a joint disease that causes pain and limitations in mobility. Current treatment of OA is focused on management of symptoms and joint replacement surgery at end stage disease, and no curative or disease-modifying treatment is available. Despite large advances over the past decades, the underlying pathophysiology of OA is still partly unclear as many factors contribute to the development of OA. In addition, the large heterogeneity of the osteoarthritic patient population suggest there might be a different underlying disease etiology in different subset populations, that may need different treatment approaches. We suspect that a large subset of patients is described by the metabolic-OA phenotype, where obesity and its subsequent low-grade systemic inflammation will accelerate the development of OA locally in the joint. Two cell types that contribute tot his low grade inflammation are monocytes and macrophages. This thesis aimed to investigate the effects of obesity-induced systemic inflammation on joint inflammation and OA development. We focused on characterizing macrophage and monocyte inflammation, with the goal to find potential targets for treatment or diagnostics, as there is a great need for better treatment options and early diagnosis tools in OA.
Bayesian SEM with Small Samples: Precautions and Guidelines
Authors:   , Smid Sanne Christina
Published: April 2023

Sometimes it can be challenging to collect enough data. Think of naturally small populations, such as people with rare diseases. Or hard to access target groups, such as people with addiction problems or undocumented migrants. However, all statistical methods require a certain amount of data to perform well. Recently, more and more often researchers with small samples switch to a Bayesian approach to deal with analysis problems. In the Bayesian framework, observed data is combined with prior knowledge (e.g., knowledge based on opinions of experts in the field or based on previous studies). This prior knowledge is captured in a distribution, the so-called prior distribution.

The studies in this dissertation show that the switch to a Bayesian approach is not without problems. Some software programs offer built-in default prior distributions, which are unfortunately not always suitable and can lead to incorrect results when samples are small. The use of Bayesian statistics in that case is not a solution to analyse a small sample. Blindly relying on built-in default priors is not an option when samples are small. The smaller the sample size, the more important the prior distributions.

In Chapter 1 of this thesis, the results are presented from an extensive systematic literature review on the performance of Bayesian and frequentist estimation methods under small samples for Structural Equation Models (SEMs). Based on this literature review, we conclude that with small samples the use of Bayesian methods with only default priors can lead to severely biased results. We end the chapter with recommendations for researchers on analysing a small sample size and on how to specify thoughtful prior distributions.

In Chapters 2 and 3, we discuss the results of simulation studies. Based on these studies we advise researchers with small samples to specify informative priors. We recommend researchers take the most careful approach possible: start with carefully constructing prior distributions; and assess the impact and robustness of the specified priors through an extensive sensitivity analysis. When researchers are not able or willing to include prior information, we advise to use the twostep method or factor regression score. These methods are a safer choice than maximum likelihood estimation, as those led to higher convergence rates without negative variances, more stable results across replications and less extreme parameter estimates than maximum likelihood estimation with small samples.

In the final chapter, we discuss in a non-technical tutorial the risks of using Bayesian estimation while blindly relying on built-in software default priors when samples are small. Also, we demonstrate an online educational Shiny app, in which users can play around with varying sample sizes and prior settings to investigate the impact of priors on the results. In addition, we provide guidelines on how to use Bayesian SEM in a thoughtful way when samples are small.
A Computational Investigation on Rho-related GTP-binding Protein RhoB through Molecular Modeling and Molecular Dynamics Simulation Study
Authors: Paul Shamrat Kumar , Metu Chowdhury Lutfun Nahar , Sutihar Sunita Kumari , Saddam Md. , Paul Bristi , Kabir Md. Lutful , Helal Md. Mostofa Uddin
Published: April 2023

Background: An indispensable member of the Rho family, RhoB is an isoprenylated small GTPases that modulate the cellular cytoskeletal organization. While DNA gets damaged, it takes part in the neoplastic apoptotic mechanism. In this study, we evaluated the structure of Rho-related GTP-binding protein RhoB due to the unavailability of 3D structure in the protein data bank database.

Results: The expected pI value of RhoB was 5.10 (acidic). The target–template alignment was computed using the GMQE value meanwhile 6hxu.1.A from Homo sapiens was selected as the template structure. The Swiss model was exploited to complete the model construction task. The structural compatibility and stability were revealed after a 100ns molecular dynamics simulation using GROMACA employing the OPLS-AA force field. Based on their fluctuating activity and their location between 100 and 110 and 140 and 150, PCA analysis discovered relevant residues.

Conclusion: By providing an insight into the biophysical phenomenon of Rho-related GTP-binding protein RhoB inhibitors, this study will assist future investigations addressing the relationship between gene mutation and abnormalities produced by protein Rho-related GTP-binding protein RhoB in apoptotic events.