bluuebunny/crossref_metadata_2025 huggingface dataset:
The Contribution of the Corpus Callosum to the Symmetrical Representation of Taste in the Human Brain: An fMRI Study of Callosotomized Patients
Authors: Polonara Gabriele , Mascioli Giulia , Salvolini Ugo , Paggi Aldo , Manzoni Tullio , Fabri Mara
Published: December 2023

The present study was designed to establish the contribution of the corpus callosum (CC) to the cortical representation of unilateral taste stimuli in the human primary gustatory area (GI). Unilateral taste stimulation of the tongue was applied to eight patients with partial or total callosal resection by placing a small cotton pad soaked in a salty solution on either side of the tongue. Functional images were acquired with a 1.5 Tesla machine. Diffusion tensor imaging and tractography were also performed. Unilateral taste stimuli evoked bilateral activation of the GI area in all patients, including those with total resection of the CC, with a prevalence in the ipsilateral hemisphere to the stimulated tongue side. Bilateral activation was also observed in the primary somatic sensory cortex (SI) in most patients, which was more intense in the contralateral SI. This report confirms previous functional studies carried out in control subjects and neuropsychological findings in callosotomized patients, showing that gustatory pathways from tongue to cortex are bilaterally distributed, with an ipsilateral predominance. It has been shown that the CC does play a role, although not an exclusive one, in the bilateral symmetrical representation of gustatory sensitivity in the GI area, at least for afferents from one side of the tongue.
Cost-Effective 3D Printing of Silicone Structures Using an Advanced Intra-Layer Curing Approach
Authors: Fay Cormac D. , Wu Liang
Published: December 2023

We present an advanced, low-cost 3D printing system capable of fabricating intricate silicone structures using commercially available off-the-shelf materials. Our system used a custom-designed, motorised syringe pump with a driving lead screw and excellent control of material extrusion to accommodate the high viscosity of silicone printing ink, which is composed of polydimethylsiloxane (PDMS), diluent, and a photo-initiator (LAP). We modified an open-source desktop 3D printer to mount the syringe pump and programmed it to deposit controlled intricate patterns in a layer-by-layer fashion. To ensure the structural integrity of the printed objects, we introduced an intra-layer curing approach that fused the deposited layers using a custom-built UV curing system. Our experiments demonstrated the successful fabrication of silicone structures at different infill percentages, with excellent resolution and mechanical properties. Our low-cost solution (costing less than USD 1000 and requiring no specialised facilities or equipment) shows great promise for practical applications in areas such as micro-fluidics, prosthesis, and biomedical engineering based on our initial findings of 300 μm width channels (with excellent scope for smaller channels where desirable) and tunable structural properties. Our work represents a significant advance in low-cost desktop 3D printing capabilities, and we anticipate that it could have a broad impact on the field by providing these capabilities to scholars without the means to purchase expensive fabrication systems.
HPV16 Intratypic Variants in Head and Neck Cancers: A North American Perspective
Authors: Gameiro Steven F. , Salnikov Mikhail Y. , Zeng Peter Y. F. , Barrett John W. , Nichols Anthony C. , Mymryk Joe S.
Published: December 2023

Human papillomavirus (HPV) is the major causative agent for cervical and many head and neck cancers (HNCs). HPVs randomly acquire single nucleotide polymorphisms (SNPs) that may become established via positive selection. Within an HPV type, viral isolates differing by <2% in the L1 region are termed “variants” and classified based on combinations of SNPs. Studies in cervical cancer demonstrate clear differences between HPV16 intratypic variants in terms of persistence of infection, tumor histology, cancer risk, and death. Much less is known about the frequency of HPV16 variants in HNC, and their effects on clinical outcomes. We combined HPV16 positive (HPV16+) HNC samples from a local Southwestern Ontario, Canada cohort with those from the Cancer Genome Atlas to create a larger North American cohort of 149 cases with clinical data and determined the distribution of intratypic variants and their impact on clinical outcomes. Most isolates were lineage A, sublineage A1, or A2, with roughly half exhibiting the T350G polymorphism in E6. Univariable analysis identified significant differences between 350T and 350G intratypic variants in clinical T, N, and O staging, as well as disease-free survival. Multivariable analysis failed to identify any clinical factor as a statistically significant covariate for disease-free survival differences between 350T and 350G. Significant differences in several measures of B-cell mediated immune response were also observed between 350T and 350G intratypic variants. We suggest that HPV genetic variation may be associated with HNC clinical characteristics and may have prognostic value.
Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNA
Authors: Mondal Somnath , Sarvari Gisoo , Boehr David D.
Published: December 2023

The Picornaviridae family comprises a large group of non-enveloped viruses with enormous impact on human and animal health. The picornaviral genome contains one open reading frame encoding a single polyprotein that can be processed by viral proteases. The picornaviral 3C proteases share similar three-dimensional structures and play a significant role in the viral life cycle and virus–host interactions. Picornaviral 3C proteins also have conserved RNA-binding activities that contribute to the assembly of the viral RNA replication complex. The 3C protease is important for regulating the host cell response through the cleavage of critical host cell proteins, acting to selectively ‘hijack’ host factors involved in gene expression, promoting picornavirus replication, and inactivating key factors in innate immunity signaling pathways. The protease and RNA-binding activities of 3C are involved in viral polyprotein processing and the initiation of viral RNA synthesis. Most importantly, 3C modifies critical molecules in host organelles and maintains virus infection by subtly subverting host cell death through the blocking of transcription, translation, and nucleocytoplasmic trafficking to modulate cell physiology for viral replication. Here, we discuss the molecular mechanisms through which 3C mediates physiological processes involved in promoting virus infection, replication, and release.
An Experimental Study of Different Stratified Water Intake Structures in a Deep-Water Reservoir
Authors: Liu Haitao , Sun Shuangke , Li Guangning , Zheng Tiegang , Shi Kai
Published: December 2023

For water temperature stratified reservoirs, stratified water intake structures are used to extract surface warm water to reduce the adverse effects of low-temperature discharge on river habitats and agricultural irrigation. A physical simulation method has been explored and used to conduct the comparative experimental study on the efficiency of the three types of intake structures: a traditional stoplog gate intake, a stoplog gate with a horizontal curtain and a vertical curtain upstream of the intake. In order to extend the laboratory results to the prototype, a similarity relationship for water temperature stratification was derived based on the principle of equal density stratification Froude number between the model and the prototype, as well as the functional relationship between water density and temperature. The similarity relationship makes it possible to simulate the same prototype density flow under different laboratory water temperature conditions, and this was confirmed through experiments conducted in several months with different water temperatures. Under constant water flow conditions, a stable target water temperature distribution can be formed in the experimental model through continuous stratified heating and real-time power regulation, to simulate the density flow generated by various intake operation in water temperature stratified reservoir. The relationships between the intake water temperature and the reference water temperature at intake depth in reservoir were analyzed to distinguish the difference of water intake efficiency. The experimental results showed that, the traditional stoplog gate has a relatively lower efficiency in extracting warm water affected by the lower edge expansion of the drag layer into the cold water zone below the intake elevation; by setting horizontal curtain to prevent the cold water from climbing below, it is helpful to improve the water intake efficiency; by setting vertical curtain in the upstream area of the intake, the velocity of warm water in the upper part of the drag layer increases, and the intake efficiency has been significantly improved. The above research provides a scientific approach for mechanism research and mathematical model validation of thermal density flow.
Isotopic and Remote Sensing-Based Characterisation of a Rainfall Event over Western Sierra de Gádor (Spain): Implications for Carbonate Aquifer Recharge
Authors: García-López Santiago , Vélez-Nicolás Mercedes , Salazar-Rojas Marcia , Ruiz-Ortiz Verónica , Sánchez-Bellón Ángel
Published: December 2023

Stable water isotopes are widely recognised as essential tools to trace processes within the hydrological cycle and to disentangle complex phenomena, such as regional–local atmospheric patterns, infer water balances or characterise the aquifer recharge. In this work, we characterised two post-summer precipitation events over the western sector of Sierra de Gádor through the analysis of the rainwater δ18O and δ2H ratios, ionic composition and, complementarily, remote sensing products to define the atmospheric circulation during the rainfall episodes. This information enabled us to discern the moisture source, formation conditions and orographic influence on the rain episodes, and to better define the origin of the groundwater recharge and its dynamics in the study area. Although the samples share a common moisture source (W Mediterranean), they display substantial differences in their isotopic compositions. Such differences are attributable to sub-cloud evaporation processes that mask their Mediterranean origin, and to the strong influence of the orography on the hydrochemical and isotopic characteristics of the rainfall at the local level. The groundwater presents a very stable isotopic content and is strongly depleted in heavy isotopes, evidencing that most of the aquifer recharge takes place at very high altitudes and primarily during winter, when the influence of evaporation is attenuated.
EPANET INP Code for Incomplete Mixing Model in Cross Junctions for Water Distribution Networks
Authors: Hernández Cervantes Daniel , Arciniega Nevárez José Antonio , Ramos Helena M. , Delgado Galván Xitlali , Pineda Sandoval Joseph Daniel , Mora Rodríguez Jesús
Published: December 2023

EPANET can be used to simulate quality on water distribution networks. The EPANET model considers that the mixing on cross junctions of pipes is complete, including the cases of two contiguous inlets and two contiguous outlets. The output concentration of this model is the same value on the two outlets. This research proposes a code to generate an INP file for EPANET but with an incomplete mixing scenario in the crossings. The cross junctions are identified, and their hydraulic and concentration conditions are analyzed for each quality time step. Bypass pipes are included in the model to remove concentrations generated by the complete mixing model, preserve continuity in water quality and ensure the correct allocation of concentration. The concentration at the outlets is obtained by a system of polynomial equations representing the incomplete mixing model as a function of the hydraulic and concentration at the junction inlets. The outlets’ concentrations are incorporated by setpoint boosters. Validations are described to demonstrate the achievement of the new code. An average relative concentration difference of up to 14% is obtained in networks with different scenarios for the two mixing models.
Community Management of Groundwater under a Private Property Regime: An Example of Institutional Local Adaptation to Overexploitation Problems in the Copiapó Aquifer, Chile
Authors: Fuster Rodrigo , Silva-Urrutia Katherinne , Escobar-Avaria Cristian , Valdés-Negroni José Miguel , Abrigo-Cornejo Gustavo , Moya-Jofré Hilda
Published: December 2023

The governance model established in Chilean water law delegates responsibility for groundwater management to private water rights owners. The Copiapó aquifer in the Atacama Region, Chile, has problems of overexploitation resulting from intensive use of the resource. This is explained by the limited information on the water availability in the aquifer and the existence of legally granted water rights whose flows exceed the rate of natural recharge. In this context, water users formed Chile’s first groundwater users’ community in the Copiapó basin for the collective administration of the aquifer. Although this organization is regulated by Chilean water law, the way in which its members participate in decision-making processes and some self-management mechanisms that they have implemented are local institutional arrangements that go beyond the rules established in the Water Code, showing this organization to be an empirical case of institutional adaptation to the overdepletion of an aquifer. The local institutional arrangements include incorporating environmental protection objectives for aquifers and wetlands, establishing an institutional arrangement that guarantees the participation in the decision-making processes of different water uses and users, developing an internal management model that promotes temporary transfers of partial volumes of a water right and carrying out studies to improve water management.
Russian literature in the education of future journalists as a program for familiarization with the tradition of educational universalism
Authors:   Department of Cultural Studies and Social Communication, Russian Presidential Academy of National Economy and Public Administration, Poelueva Lyubov Aleksandrovna , Indrikova Anastasiya Aleksandrovna ,   Department of English for Professional Communication, Faculty of Modern Languages, National Research Mordovian State University named after N.P. Ogarev
Published: December 2023

The authors describe the relevance of the status of Russian classical literature as a program for educating the most important values of educational universalism for Russia. The education of future journalists should take into account this strategic resource for the reproduction of the Russian intellectual elite to the greatest possible extent. The article shows that in Russia, literature has determined and directed the main direction of sociocultural and civilizational development for centuries. This explains the concern of the education-oriented part of our society about the return of young people to reading Russian classics as a socialization program based on high spiritual ideals and values that manifest themselves through classical literary texts.
“Showmanship” as a principle of art: to the problem of the content of the concept
Authors:   Department of Art, Moscow Humanitarian University, Morozova Elena Ivanovna
Published: December 2023

The purpose of the study is to develop an understanding of the concept of “entertainment” as a philosophical category. The author connects the concept of “spectacle” with the modern concepts of “image”, as well as with what ancient thinkers called “prosopon” and “aletheia”. Thus, entertainment is transformed in the human mind as something seen, heard, felt through smells, taste, hearing, tactility , but included in the figurative sphere of the personality. The author seeks to show that the concept of “entertainment” is one of the basic concepts and principles of postmodernity.
Tasks associated with FSB activities at the present stage
Authors:   Faculty of Law, Moscow University for the Humanities, Nefedova Aleksandra Gennadievna , Gainutdinova Ekaterina Irekovna ,   Department of Criminal Law and Special Disciplines, Moscow University for the Humanities
Published: December 2023

The article examines current problems faced by the Federal Security Service of the Russian Federation (FSB) at the present stage. Topics covered are the changing global political situation, technological progress, cyber threats, and the need to modernize approaches to security. Internal challenges related to strengthening corporate culture, combating corruption, and the formation of a new type of professional training of specialists were considered as well.
Organization of cultural and leisure activities of elderly people in the Republic of Bashkortostan
Authors:   FSBEI HE Ufa University of Science and Technology, Bolshakova N. L. , Klochkova M. A. ,   Social Work, FSBEI HE Ufa University of Science and Technology, Sterlitamak, Republic of Bashkortostan
Published: December 2023

The article reveals the main directions of cultural and leisure activities of senior citizens in the Republic of Bashkortostan. It is determined that itconditions for their active participation in professional, social, and public life through socially oriented institutions. is necessary to create
Gerontostereotypes as a biopsychosocial phenomenon in the context of student training in the system of social and medical care
Authors:   Department of Social Work, Economics and Bioethics FSBEI HE Yaroslavl State Medical University, Mokicheva N. A. , Startseva O. N. ,   Department of Social Work, Economics and Bioethics, FSBEI HE Yaroslavl State Medical University
Published: December 2023

In modern conditions, the priority direction of the state social policy is the development of long-term assistance to the elderly population in institutions of social and medical care. Often in these institutions there are cases of negative attitude towards the elderly, which is a consequence of the gerontostereotypes formed in society. This requires the training of specialists to work in the system of social and medical care at a high professional level. The article analyzes the main gerontostereotypes among students of the higher medical educational institution. It was revealed that the most significant gerontostereotype influencing the formation of ageism in future specialists is a negative stereotype regarding the health of elderly people. The article presents ways to overcome stereotypical attitudes in the framework of the educational process.
The notion of «medical report», its importance and application in the field of labor
Authors:   Department of Labor Law of the Federal State Budgetary Educational Institution of Higher Education ", Paramonova S.V. ,   Ural State Law University named after V.F. Yakovlev",   , Yekaterinburg
Published: December 2023

The state of health of an employee, which entails the onset of legally significant consequences for labor relations, must be certified by a medical conclusion. At the same time, the concept of «medical conclusion» is not defined at the legislative level and, as a result of assessing the state of health, may be contained in different documents. This circumstance entails difficulties in law enforcement, and the blurred outline of the content detracts from the significance of the notion for the world of work. The request for certainty can be satisfied by summarizing law enforcement practice and formulating clarifications at the level of the Supreme Court of the Russian Federation, as well as alteration the provisions of labor legislation.
Mechanism for the protection of social security rights in Russia and some EAEU countries
Authors:   Department of International Law, The Diplomatic Academy of the Russian Foreign Ministry, Gusev A. , Batusova E.S. ,   Department of Public Law, Faculty of Law, National Research University Higher School of Economics
Published: December 2023

The welfare State should ensure the functioning of the mechanism for the protection of social security rights. The adoption of a codified act in the field of social security is one of the important issues of systematization and establishment of benefits, guarantees in this area, the development of a common approach to the protection of social security rights. An analysis of the legislative experience of the EAEU countries regarding the codification of this legislation, as well as mechanisms for the protection of such rights, can serve as a basis for the development of the Russian Code. The study of the legislative provisions regulating the activities of the social protection inspector in the Republic of Kazakhstan can serve as a basis for optimizing legislation in this area in the Russian Federation and the implementation of regulations on the powers of the social protection inspector.
Jurisprudence: pay
Authors:   the Practice of Labor and Migration Law of the Pepelyaev Group company, Moscow, Zhizherina Yu. Yu.
Published: December 2023

The review presents court decisions on disputes on remuneration in local acts and employment contracts, on the timing of salary payments, etc.
Influence of targeted protein-vitamin-mineral concentrates on the beef traits of steers of different breeds
Authors:   Kurgan State Agricultural Academy named after T. S. Maltsev – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo, Uskov G. E. , Tsopanova A. V. ,   Kurgan State Agricultural Academy named after T. S. Maltsev – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo, Kostomakhin N. M. ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Zakolyapin I. A. ,   Kurgan State Agricultural Academy named after T. S. Maltsev – a branch of the Federal State Budgetary Educational Institution of Higher Education “Kurgan State University”, Russia, Kurgan region, Lesnikovo
Published: December 2023

Currently, research is relevant to the development and testing of recipes for proteinvitamin- mineral concentrates (PVMC) based on extruded soybeans and synthetic nitrogen-containing substances, which allows optimizing the protein and mineral nutrition of animals. The purpose of the research was to study the infl uence of targeted PVMC on meat productivity and beef quality of steers of diff erent breeds in the Kurgan region. The eff ect of PVMC on meat productivity was studied on steers of Black-and-White and Aberdeen-Angus breeds. For this purpose, three groups were formed in each breed, which included 15 heads of steers aged 12 months. The steers of the control group were fed PVMC -65, the steers of the 1st experimental group were fed the experimental PVMC-65K, and the 2nd experimental group were fed PVMC-65KB at 200 g per 100 kg of live weight. Feeding targeted PVMC-65KB had a positive eff ect on the meat productivity of steers. Over 150 days of fattening, the live weight of steers of Black-and-White breed was 8,9 % higher, and steers of Aberdeen-Angus breed was 6,1 % higher compared to the control herdmates. The slaughter yield for steers of the experimental groups received PVMC-65KB was 53,7 % for steers of Black-and-White breed and 57,3 % for steers of Aberdeen-Angus breed, which was 1,62 and 1,56 abs.% more than their herdmates from control groups. The proportion of muscle tissue in the experimental groups of steers received PVMC-65KB was higher by 1,73 abs.% in Black-and-White and by 2,37 abs.% in Aberdeen-Angus compared to control herdmates. It was found that optimization of feeding of steers stimulated muscle raising in animals of the experimental groups, in the same time in the control group at this age the deposition of adipose tissue had already begun.
Antioxidant feed additive Dihydroquercetin in the feeding of broiler chickens
Authors:   Federal State Budgetary Educational Institution of Higher Education “Mari State University”, Russia, Republic of Mari El, Yoshkar-Ola, Petrov O. Yu. , Kuzmina N. N. ,   Federal State Budgetary Educational Institution of Higher Education “Mari State University”, Russia, Republic of Mari El, Yoshkar-Ola
Published: December 2023

Currently, the production of poultry products intended for healthy nutrition is relevant. Consumption of such products allows us to stabilize the metabolism in the body and improve human health. Raw meat is susceptible not only to rapid microbiological spoilage, but also to oxidative spoilage, which preservatives help combat. Oxidative processes reduce the shelf life of fi nished products due to the deterioration of organoleptic characteristics and nutritional value of products. Therefore, one of the modern trends in the production of poultry products for a healthy diet is a focus on the use of natural feed additives when obtaining raw meat, through the lifetime development of quality. The purpose of the work was to study the antioxidant feed additive Dihydroquercetin in feeding of broiler chickens. When carrying out a scientific and farm experiment using the method of analogous groups, 4 groups of broiler chickens (control and three experimental) were formed at one day of age. Chickens of the 1st control group received only special compound feed as the main diet (MD), chickens the 2nd experimental group in addition to the MD received the antioxidant additive Dihydroquercetin in the amount of 0,50 g per 100 g of compound feed, chickens the 3rd group received 0,75 g per 100 g of compound feed and chickens of the 4st group received 1 g per 100 g of compound feed. It was found that the studied antioxidant additive contributed to better realization of the productive potential of poultry, increasing the livability of livestock, increasing meat productivity and improving the quality of meat raw materials. It has been proven that there is no negative impact of the feed additive on the main safety indicators of broiler chicken meat. Additional reserves have been identifi ed for increasing the economic effi ciency of broiler chickens rearing and producing of meat products from the resulting raw materials.
HUBUNGAN ANTARA TEKANAN DARAH DIASTOLE IBU DENGAN BERAT BADAN LAHIR BAYI PADA IBU YANG MELAHIRKAN DENGAN UMUR KEHAMILAN ATERM DI WILAYAH KERJA PUSKESMAS KUBUTAMBAHAN II BULELENG
Authors: Arthayani Ni Putu Neysa Putri , Sriasih Ni Gusti Kompiang , Ningtyas Listina Ade Widya
Published: December 2023

As much as 60–80% of the infant mortality rate that occurs is caused by low birth weight. This study aims to determine the relationship between diastolic blood pressure and birth weight at the Kubutambahan II Community Health Center, Buleleng. This research is an analytical research with a cross sectional approach. The research was carried out in February – March 2022. The population of this research study were all newborn babies in the work area of the Kubutambahan II Health Center. The research sample used was 55 respondents. The results of the univariate analysis showed that 81.8% of mothers had normal blood pressure, and 76.4% of babies had normal birth weight. The results of the bivariate test showed that there was a relationship between diastolic blood pressure and birth weight, with a value of p = 0.003. The OR value was 8.143 (95% CI: 1.817-36.500). The conclusion of this study, 55 respondents showed a significant relationship between maternal diastolic blood pressure and the baby's birth weight. The results of the research hope that health workers will be more careful in detecting early the signs and dangers of pregnancy, especially hypertension.
Hubungan Pengetahuan dengan Sikap Ibu Hamil Tentang Pemanfaatan Buku KIA di Puskesmas Buleleng I
Authors: Indrayani Indrayani , Tedjasulaksana Regina , Darmapatni Made Widhi Gunapria
Published: December 2023

The KIA Handbook is a health record book containing maternal and child health records as well as various information on how to maintain and care for maternal and child health. In fact, utilization for pregnant women is still low. The purpose of this study was to determine the relationship between knowledge and attitudes of pregnant women about the use of KIA Handbook at the Buleleng I Public Health Center. The study design used a cross sectional study. The research sample was pregnant women, totaling 73 people. The data collection instrument was in the form of a questionnaire regarding knowledge and attitudes about the use of KIA Handbook. The data were analyzed by the Kendall tau test b. The results showed that 43 pregnant women (58.9%) had a good level of knowledge about  use of KIA Handbook. A total of 50 pregnant women (68.5%) had a positive attitude towards the use of KIA Handbook. The results of the bivariate analysis using the Kendall tau b test and the p value = 0.000. This means that there is a relationship between knowledge and attitudes of pregnant women about the use of KIA Handbook at the Buleleng I Public Health Center. The results of this study are expected that health workers always inform mothers about the use of KIA Handbook.
SCIENTIFIC ORGANIZATION OF LABOR AS ONE OF THE MAIN ELEMENTS OF THE SUSTAINABLE DEVELOPMENT OF RAILWAY TRANSPORT
Authors:   Russian University of Transport (MIIT), Moscow, Russia, Nikitin V.N.
Published: December 2023

The object of the study is the company JSC Russian Railways, which provides infrastructure and locomotive traction services in railway transportation. The subject of the paper is the scientific organization of labor in railway transport. The purpose of the study is to determine the range of opportunities and influence of the scientific labor organization (taking into account the use of digital technologies) to increase the productivity and quality of the company’s work, and to ensure the sustainable development of the industry as a whole. The relevance of the study is due to the fact that nowadays railway transport plays an important role in the global economy and ensuring interregional links between various economic entities. The methodological basis of the research is domestic and foreign scientific sources; the information basis is the corporate reporting of JSC Russian Railways and publicly available statistical data. The research results and proposals presented in the article can contribute to the sustainable development of the company and increase its competitiveness in the transport market, as well as can be used by researchers, students, graduate students, teachers, employees of transport organizations, and other sectors of the economy, whose scientific, educational and practical activities are related to the development and implementation of principles and mechanisms of scientific organization of labor. Conclusions are drawn about the need to improve the tools of scientific organization of labor for the purposes of sustainable development.
HR SERVICE MATURITY AS A CONDITION FOR CLIENT-CENTRICITY WHEN WORKING WITH INTERNAL CUSTOMERS IN PUBLIC AUTHORITIES
Authors:   All-Russian Research Institute of Labor, Moscow, Russia, Sladkova N.M. , Voskresenskaya O.A. ,   All-Russian Research Institute of Labor, Moscow, Russia, Petrova S.A. ,   All-Russian Research Institute of Labor, Moscow, Russia
Published: December 2023

The article discusses the results of monitoring the maturity of the HR services of federal executive authorities in 2023 as part of the implementation of the federal project “State for the People.” The purpose of the paper is to assess the maturity and identify barriers of the HR services work of public authorities using comprehensive monitoring technologies to determine the priorities for the transformation of personnel services in the context of introducing the principles of client-centricity in the public administration system of the Russian Federation. The research methods are document analysis, automated surveys to collect monitoring data, semi-automated processing and analysis (including correlation), and the development of standard recommendations for authorities on the transformation of HR. As a result, a generalized characteristic of the level of maturity of the HR services of federal executive authorities was obtained, and the role of the HR services at various stages of the life cycle and their compliance with the goals and objectives of HR as a whole was determined. It is concluded that there are positive prerequisites for successful transformation and ensuring the implementation of the principles of client-centricity of the HR services, despite the difference in their level of maturity. Typical barriers of HR and ways to overcome them are given, and approaches to implementing a transformation project are considered. The research materials are addressed to representatives of state and municipal bodies, a wide range of specialists interested in tools and technologies for assessing personnel performance and, in particular, the maturity of the HR services, including their role, organizational and functional structure, competencies, resource provision, and other characteristics.
ON THE ISSUE OF (IM)MOBILITY OF LABOUR FORCES IN RUSSIA AND IN THE WORLD
Authors:   Free Economic Society of Russia, Moscow, Russia, Kamari D.M.
Published: December 2023

The subject of the study is the impact of the introduction of innovative technologies on changes in migration activity. The purpose of the study is to clarify the role of information infrastructure in the sedentarization of labor resources. The relevance of scientific research is due to the development of information and communication technologies, which are changing labor relations. The scientific novelty lies in the attempt to explain the influence of telecommunication technologies on resolving the issue of internal migration and shadow employment. The research methods are economic and comparative analysis. In the course of the study, the author obtained the following results: a high level of internal migration persists due to the underdeveloped telecommunications infrastructure and low data transmission speed. The author concludes that the creation of free high-speed Internet zones in regions with high unemployment and levels of informal employment can lead to a decrease in the shadow sector and an increase in the investment attractiveness of the region.
ORGANIZED RECRUITMENT OF LABOR MIGRANTS AND FACTORS AFFECTING ITS DEVELOPMENT
Authors:   Primakov National Research Institute of World Economy and International Relations of the Russian Academy of Sciences Moscow, Russia, Komarovsky V.V.
Published: December 2023

The subject of the study is the factors on which the development of an organized recruitment of labor migrants depends. The purpose of the paper is to analyze the modern practice of using organizational recruitment as a tool for migration regulation. The relevance of the study is due to the role of organizational recruitment to meet the changing demand of the Russian labor market for foreign labor. The scientific novelty is determined both by the limited number of studies of this kind and by the increased interest in the prospects for improving the forms of organized recruitment in the new realities of migration processes. The research methods are analysis, systematization, synthesis, and classification of the objects under study. The following research results were obtained: the organizational and legal framework for using the potential of organizational recruitment was established. Changing demand for attracting various categories of labor migrants requires further development of organizational recruitment. This should happen, first of all, by moving the training of applicants to the countries of origin. Taking into account the interests of the receiving party in terms of securing selected specialists in the proposed jobs deserves serious attention. The author concludes that the importance of organizational recruitment is growing as an effective tool for meeting the current and future demand of the labor market for in-demand foreign workers. The practical interest of the study is determined by the possibility of using the presented results to improve the organization of attracting labor migrants from specific countries to Russia.
Sistemas silvopastoriles para la producción de rumiantes en pastoreo
Authors: Hernández Armando Pacheco , Bautista Israel Bautista , Chávez Lisandro Morales , Ramírez Ángel Enrique Carlos , Mateo Aarón Beltrán
Published: December 2023

Los sistemas Silvopastoriles (SSP) son una opción tecnológica sostenible, que investigaciones recientes los impulsan para mejora de la producción pecuaria, por su influencia sobre el comportamiento del ganado, incremento de la biodiversidad, potencial productivo y valor nutritivo de las plantas presentes en los potreros. Sin embargo, existen poco uso del potencial que tienen estos sistemas en la alimentación de rumiantes en los sistemas de producción por lo que el presente artículo tiene la finalidad de realizar una argumentación teórica de principales tecnologías que se pueden implementar como alternativa para la alimentación de rumiantes en estos sistemas, así como el mejoramiento de la alimentación de estas especies mediante la utilización de sistemas Silvopastoriles
Exploring into the Unseen: Enhancing Language-Conditioned Policy Generalization with Behavioral Information
Authors: Cao Longhui , Wang Chao , Qi Juntong , Peng Yan
Published: December 2023

Generalizing policies learned by agents in known environments to unseen domains is an essential challenge in advancing the development of reinforcement learning. Lately, language-conditioned policies have underscored the pivotal role of linguistic information in the context of cross-environments. Integrating both environmental and textual information into the observation space enables agents to accomplish similar tasks across different scenarios. However, for entities with varying forms of motion but the same name present in observations (e.g., immovable mage and fleeing mage), existing methods are unable to learn the motion information the entities possess well. They face the problem of ambiguity caused by motion. In order to tackle this challenge, we propose the entity mapper with multi-modal attention based on behavior prediction (EMMA-BBP) framework, comprising modules for predicting motion behavior and text matching. The behavioral prediction module is used to determine the motion information of the entities present in the environment to eliminate the semantic ambiguity of the motion information. The role of the text-matching module is to match the text given in the environment with the information about the entity’s behavior under observation, thus eliminating false textual information. EMMA-BBP has been tested in the demanding environment of MESSENGER, doubling the generalization ability of EMMA.
СУЧАСНІ РЕФЛЕКСІЇ ІДЕЙ ГРИГОРІЯ СКОВОРОДИ ПРО ЛЮДСЬКЕ ЩАСТЯ: ДУМКИ НАУКОВЦЯ І ПОГЛЯДИ УКРАЇНСЬКИХ СТУДЕНТІВ
Authors: Дічек Наталія
Published: December 2023

Аби з’ясувати чи є у ХХІ ст. науковий інтерес (сковородознавство
до самобутньої спадщини славетного українського мислителя ХVІІІ ст.
Григорія Савича Сковороди (1722‒1794), здійснено джерельний пошук
й історіографічний огляд українських і зарубіжних публікацій (з кінця ХVІІІ ст.
по сьогодення) про його внесок у філософсько-гуманітарну думку. Пояснимо,
що огляд дає підстави обстоювати наявність не лише сковородіани
як сукупності різноманітних дослідницько-інтерпретаційних різномасштабних
праць життя і творчості Г. Сковороди, а на основі огляду цих публікацій
й наявність сковородознавства як окремої галузі гуманітаристики, розвинутої
насамперед в Україні. Це перший висновок.
Xenogeneic Transplantation Promoted Human Exosome Sequestration in Rat Specific Organs
Authors: Mobarak Halimeh , Mahdipour Mahdi , Ghaffari-Nasab Arshad , Rahbarghazi Reza
Published: December 2023

Purpose: Here, we aimed to study the distribution pattern of normal and cancer xenogeneic exosomes (Exos) and possible interspecies reactions in a rat model. Methods: Exos were isolated from normal Human umbilical vein endothelial cells (HUVECs) and MDA-MB-231 breast cancer cells. Diameter size and zeta potential distribution were studied using dynamic light scattering (DLS). The morphology of isolated Exos was monitored by scanning electron microscopy (SEM) images. Using western blotting, protein levels of exosomal tetraspanins were detected. For the in vivo study, Dil-labeled normal and cancer Exos were injected into the tail vein (100 µg exosomal protein/rat) three times at 1-hour intervals. After 24 hours, rats were euthanized and the cellular uptake of Exos was monitored in different organs using immunofluorescence staining (IF). Results: The size distribution and mean zeta potential of HUVEC and MDA-MB-231 cells Exos were 80±29.94 and 64.77±25.49 nm, and −7.58 and −11.8 mV, respectively. Western blotting revealed CD9, CD81, and CD63 in normal and cancer Exos. The SEM images exhibited typical nano-sized round-shape Exo particles. IF staining indicated sequestration of administrated Exos in splenic tissue and lungs. The distribution of Exo in kidneys, aorta, and hepatic tissue was less. These features were more evident in the group that received cancer Exos. We found no obvious adverse effects in rats that received normal or cancer Exos. Conclusion: Normal and cancerous xenogeneic human Exos can be sequestrated prominently in splenic tissue and lungs. Novel delivery approaches and engineering tools are helpful in the target delivery of administrated Exos to the injured sites.
Novel Memories of Motherhood: Childbirth Lived Experiences of Mothers with Coronavirus Disease 2019 (COVID-19)
Authors: Abdollahpour Sedigheh , Akbari Azam , Khadivzadeh Talat
Published: December 2023

Introduction: The critical coronavirus pandemic presents a global challenge with dimensions yet unknown, underscoring the essential need to comprehend the lived experiences, especially for vulnerable groups. This study delves into the childbirth experiences of mothers dealing with coronavirus disease 2019 (COVID-19). Methods: Employing hermeneutic phenomenology, this qualitative research was conducted at Mashhad University of Medical Sciences (Iran). Purposeful sampling involved 16 mothers with maximum variation. Unstructured telephone interviews collected data, analyzed using the Diekelman approach. Results: Unveiling the theme "Novel Memories of Motherhood," four central themes emerged: "The Missing Link in Quality Care," "Coronavirus Stigma," "A lonely mother in quarantine," and "Cascade of Psychological Trauma." Conclusion: COVID-19 acts as an intervening factor, distorting routine care and delivery programs. The focus for service providers attending to mothers in labor should extend beyond physical care, encompassing the elimination of coronavirus-related stigma and prioritizing psychological attention. This holistic approach is crucial for maintaining quality care standards.
Use of Phototherapy and Er-YAG Laser in the Management of Mandible Osteoradionecrosis: A Case Report
Authors: de Freitas Larissa Couto , Kawamoto Elenice Lika , Souza Ana Maria Aparecida , Kawasakami Paulo Yataro , Simões Alyne Gonçalves , Azevedo Luciane Hiramatsu
Published: December 2023

Introduction: Osteoradionecrosis (ORN) is a secondary complication from radiotherapy, which is difficult to manage and significantly reduces the life quality of the affected patients. Case Report: A 59-year-old female patient, diagnosed with infiltration by squamous cell carcinoma in the left cervical region, underwent adjuvant cervical-facial radiotherapy with a total dose of 66.6 Gy of radiation. Eight years after the diagnosis, the patient underwent multiple extractions and, subsequently, the installation of osseointegrated implants, evolving to extensive intraoral bone exposure associated with oral cutaneous fistula. The patient was initially exposed to photobiomodulation therapy (PBMT), with a low-power laser at wavelengths of 660 nm and 808 nm, and thereafter to antimicrobial photodynamic therapy (aPDT). After an improvement in the clinical condition and resolution of the oral cutaneous fistula, a surgical procedure with the Er: YAG laser was performed to remove the remaining necrotic bone. Once the ORN condition was completely treated, the patient’s oral rehabilitation was implemented by the installation of an upper mucous-supported total prosthesis and a lower implant-supported prosthesis. Conclusion: The patient is in a clinical follow-up and has no signs of bone necrosis recurrence, suggesting that low and high-power laser treatment can be an effective therapeutic alternative to resolve this condition.
Tautomers of 2,4-dihydro-3H-1,2,4-triazol-3-one and their Composites with NTO - A DFT Treatment
Authors: Türker Lemi
Published: December 2023

In the present density functional study, some tautomers of 2,4-dihydro-3H-1,2,4-triazol-3-one (1,2-dihydro-1,2,4-triazol-3-one) and their composites formed with NTO have been considered within the constraints of the density functional theory and the basis set employed (B3LYP/6-311++G(d,p)). The triazolone considered is the precursor of NTO in various methods. It may exhibit 1,3-proton tautomerism. Various energies, QASR, quantum chemical and spectral properties have been harvested and discussed. All the considered species have exothermic heat of formation and favorable Gibbs free energy of formation values at the standard states and they are stable electronically. Although most of the composites considered exhibit a directed interaction between their partners, one of them possesses perpendicular (T-type) orientation. Certain hydrogen bondings between the tautomers and NTO occur at different extents, depending on the particular tautomer involved in the composite. Both of the components have hydrogen bond donor and acceptor properties except composite NTO+T2, in which the tautomer is the hydrogen bond donor and NTO is the acceptor. The tautomers absorb in the UV region of the spectrum like NTO, whereas in all the composites appreciable changes in the appearance of the spectra happen and certain degree of bathochromic effect occurs as compared to the respective spectra of the partners.
KINERJA KARYAWAN PT NOBI PUTRA ANGKASA DIPENGARUHI OLEH DISIPLIN KERJA MELALUI LINGKUNGAN KERJA
Authors: Adya Meivy Khanza  , Eddy Sanusi. S
Published: December 2023

This study aims to determine employee performance which is influenced by work discipline directly or indirectly through the work environment as an intervening variable at PT Nobi Putra Angkasa. The method used in this research is a quantitative approach method. Sampling technique using a census. Method of analysis using path analysis techniques The results showed that 1) Work discipline has a positive and significant effect on employee performance 2) Work environment has a positive and significant effect on employee performance 3) Work discipline has a positive and significant effect on work environment. 4) Employee performance is not influenced by work discipline through the work environment.