bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between Larva Free Index (LFI) and healthy house with DHF incidence rate in Banyuwangi Regency, 2022
Authors: Naura Qonita  , Yusva Dwi Saputra
Published: June 2023

Dengue hemorrhagic fever is one of society's most frequent health issues, causing various health issues. DHF is the most frequent infectious illness in Indonesia, with many cause variables, such as LFI and healthy households, influencing the frequency of DHF cases. This study was conducted to determine the relationship between the Larvae Free Index and healthy houses with the incidence rate of DHF in Banyuwangi Regency in 2022. This research is a cross-sectional study using secondary data obtained from relevant agencies. Variables included dengue incidence rate (DHF IR), Larvae Free Index (LFI), and healthy houses in Banyuwangi Regency in 2022. Data analysis was conducted using the Pearson Correlation Test to determine the relationship between variables. Mapping and descriptive analysis were also performed on the data to provide an overview of case conditions. The results showed that ABJ (p-value = 0.506) had no significant relationship with DHF IR. Similarly, healthy houses (p-value=0.992) also did not have a relationship with the DHF IR in the Banyuwangi regency in 2022. This condition may occur because there is a possibility that the variables studied do not directly affect the DHF IR, but there are also other variables that support it. Despite the lack of a significant association, it is vital to continue monitoring activities connected to LFI and healthy houses to enhance health status and DHF prevention in the community.
Phänomene der Entgrenzung und ihre Bedeutung für professionelle Beziehungen
Authors: Spiegler Lara , Beeck Felicitas , Dörr Margret
Published: June 2023

Entgrenzungsmomente sind allgegenwärtig. In zwischenmenschlichen Beziehungen liegt ihnen ein hohes affektiv-sinnliches Wirkkraftpotenzial inne. Im Beitrag werden anhand von empirischem Datenmaterial interund intrasubjektive Dynamiken einer professionellen Beziehung, die zunächst dadurch auffällt, dass in ihr die symbolische Ordnung der Zweigeschlechtlichkeit entgrenzt wird, tiefenhermeneutisch analysiert.
Tertiale Grenzbegegnungen
Authors: Will Jakob Christoph
Published: June 2023

Der Beitrag stellt zwei unterschiedliche Grenzformate vor, die sich jeweils auf unterschiedliche Verständnisse relationaler und absoluter Grenzen beziehen, die beide für Soziale Arbeit relevant werden. Dabei soll nach deren Verhältnis zueinander gefragt werden, welches sich nicht als ein binäres, sondern tertiäres Beziehungsgeflecht zeigt. Schließlich soll auf die Bedeutung der Tertialität für Soziale Arbeit in der spannungsreichen Dynamik zwischen den beiden Grenzformaten hingewiesen werden.
Takt
Authors: Hierdeis Helmwart
Published: June 2023

Ausgehend von aktuellen Szenen fragwürdiger Kommunikation führt der Beitrag über erste Zeugnisse der Sensibilisierung für das Thema »Takt« in der Aufklärung zu einer vorwissenschaftlichen Begründung taktvollen Umgangs am Ende des 18. Jahrhunderts durch Adolph Freiherr von Knigge. Er verfolgt ferner die »Eingemeindung« des Begriffs durch die pädagogische Theorie Johann Friedrich Herbarts und geht der Funktion des »Takts« als »Gefühl für den richtigen Moment« im Konzept der Psychoanalyse nach. Am Ende steht, auf der Basis von Überlegungen zum Fremdheitsdiskurs, eine Funktionsbestimmung des »Takts« als Möglichkeit, zwischenmenschliche Grenzen als Grenzen zwischen sich stets Fremden zu moderieren.
An den Grenzen des »informed consent«
Authors: Wininger Michael
Published: June 2023

Da sich die Spezifität der psychoanalytischen Beziehung im Intimen bzw. in der Subjektivität des Einzelfalls erschließt, ist diese auch nur über intime Einblicke in konkrete Beziehungsprozesse zu ergründen und zu vermitteln. Insofern bewegt man sich in der Veröffentlichung von Kasuistischem in einem Spannungsfeld zwischen notwendiger Verpflichtung und der (potenziellen) Verletzung von Intimitätsgrenzen und Verschwiegenheitsverpflichtungen, die weit über das Ende der eigentlichen gemeinsamen Arbeit von PatientInnen und PsychoanalytikerInnen hinausreichen. Innerhalb der Psychoanalyse wurde in der jüngeren Vergangenheit dazu ein differenzierter Diskurs geführt, der bislang noch nicht umfangreicher im Bereich der Psychoanalytischen Pädagogik bzw. anderer psychosozialer Arbeitsfelder rezipiert wurde. Der Beitrag zeichnet zentrale Linien der psychoanalytischen Diskussion nach, stellt einige Strategien zum Umgang mit dem benannten Dilemma vor und diskutiert diese im Hinblick auf ihre Vorund Nachteile. Ausgehend davon wird gezeigt, dass all diese Strategien hilfreiche Ansätze im Umgang mit Kasuistik beinhalten können, WissenschaftlerInnen aber nicht von der herausfordernden inneren Arbeit entheben, eigene Gefühle der Schuld, Angst und Scham zu regulieren und eine förderliche Balance zwischen Selbstzensur und der nötigen Intimität des Einblicks zu finden.
»Ich bin sicher, Großvater hätte das gebilligt«
Authors: Hristeva Galina , Kaufhold Roland
Published: June 2023

Der Artikel führt in das Leben von Sigmund Freuds Enkel Anton Walter Freud ein. Nach der Rekonstruktion seiner Jugend in Wien, der Familienbeziehungen und der Ereignisse, die zu der Emigration der Familie nach England führten, sowie nach der Darstellung der für Anton Freud sehr schwierigen Jahre bis zum Ende des Zweiten Weltkrieges liegt der Schwerpunkt der Untersuchung auf Anton Walter Freud als Nazijäger. Im Rahmen seiner Tätigkeit als britischer Armeeangehöriger des War Crimes Investigation Team (WCIT) verhörte Freud Nazitäter wie z.B. Anton Tesch, einen Angehörigen von der Firma Tesch & Stabenow. Tesch war verantwortlich für die Lieferung des Zyklon-B-Gases, mit dem in bestialischer Weise Millionen von wehrlosen Juden in deutschen Vernichtungslagern wie Auschwitz und Sobibor ermordet wurden. Einen weiteren Schwerpunkt des Artikels stellt die Analyse des Films Nazijäger – Reise in die Finsternis dar (2022, Buch: Hannah und Raymond Ley; Regie Raymond Ley, Produzent Michael Kloft), der vom Ersten am 16. Januar 2022 ausgestrahlt wurde. Der Film und die vorgelegte Filmanalyse nehmen Anton Walter Freuds Rolle bei der Aufklärung der im KZ Neuengamme an Kindern verübten sadistischen Experimente und Mordhandlungen ins Visier. Der Bericht über Freuds Rückkehr in das bürgerliche Leben nach 1945 rundet den Text ab.
Einwilligung in das Unglück?
Authors: Eckert Andrea
Published: June 2023

Einige Entwicklungen der letzten 20 Jahre geben Anlass zur Hoffnung, dass sich tatsächlich in der Weltgesellschaft etwas verbessert hat im Verständnis von sexueller Gewalt und von sexualisierter Macht. Dennoch zeigt sich, dass es nicht nur gesellschaftlich, sondern auch aus der psychoanalytischen Theorie heraus in bestimmten Konstellationen Barrieren dagegen gibt, Missbrauch als solchen zu realisieren und seine Folgen zu begreifen, vor allem wenn er ohne Gewalt und mit Einwilligung des Opfers geschieht. Eine Auseinandersetzung mit den Motiven der TäterInnen wird für wichtig gehalten. Es wird dargestellt, warum auch Adoleszente des Schutzes vor erwachsener Sexualität bedürfen.
Effectiveness of Combination of Tamarind and Saffron as Antidiabetic
Authors: Hilda Hilda , Nasution Pratiwi Rukmana
Published: June 2023

According to the International Diabetes Federation, 537 million people are currently living with diabetes. There are 316 million people with impaired glucose tolerance at high risk, an alarming number expected to reach 783 million people by 2045. Society's tendency to return to nature is a prospective condition for developing research on biodiversity-based plants. Based on the research results, tamarind leaves are rich in flavonoids, saponins, and tannins, and saffron contains the active compounds crocin, crocetin, and precision, which can be candidates for antioxidants that have a significant effect on blood glucose levels. This antidiabetic research includes research live (test animals) by measuring blood glucose levels. The results showed that tamarind leaf extract and saffron were effective as antidiabetics in male mice induced with Streptozotocin. All extract groups tested single doses of EDAJ, ES, and combination doses of EDAJ and ES ((75:25), (50:50) (25:75)) showed the potential to reduce blood sugar levels >50%. The ES group with a single dose of 100:0 showed significant effectiveness in reducing blood sugar levels from the 6th day until the end of the study. These results are then expected to provide information to the public regarding the potency, effective dose, and working mechanism of using tamarind and saffron as antidiabetics so that they can be a solution to improve the quality of life of diabetes patients, control non-communicable diseases and reduce treatment costs. 

 

Keywords: Crocus sativus, Diabetes mellitus,  Mus musculus, Saffron, Tamarind leaf 
Association of Secondhand Smoke Exposure During Pregnancy and Umbilical Cord Blood Vitamin D Levels with Newborn Weight
Authors: Nasution Izmi Fadhilah , Sulastri Delmi , Karmia Hudila Rifa
Published: June 2023

Newborn weight is an important predictor of the growth and survival of infants. Low birth weight affects newborns at risk of experiencing health problems and the risk of death Women in developing countries experience many pregnancies with malnutrition, and exposure to cigarette smoke can reduce micronutrient deficiencies. Exposure to cigarette smoke damages the health of pregnant women and their fetuses. Vitamin D is a micronutrient that supports every stage of pregnancy, the placenta, and the fetus to achieve a healthy pregnancy. This study aims to determine the association of secondhand smoke exposure during pregnancy and umbilical cord blood vitamin d levels with newborn weight. This research is a quantitative analytic observational study with a Cross-Sectional Study design. This research was conducted at Hermina Padang Hospital. The time of research was carried out from 14 December 2022 to 10 January 2023. The population in this study were all mothers who gave birth at Hermina Hospital. The sampling technique uses non-probability sampling. The number of samples in this study was 55 samples. Data analysis using the ANOVA test. The study results showed a significant mean difference between the level of exposure to cigarette smoke and birth weight. This can be seen from the p-value <0.05 (p=0.002) and no significant difference in the average blood vitamin D levels. Umbilical cord with birth weight, can be seen from the p-value>0.05 (p=0.484) at Hermina Padang Hospital. It is recommended that health workers provide counseling about exposure to cigarette smoke to pregnant women and mothers to pay attention to meeting the needs of vitamin D during pregnancy.

  

Keywords:  Newborn Weight, Secondhand Smoke Exposure, Vitamin D , Newborn Weight
Meta-Analysis: Risk Factor Analysis of Tuberculosis Incidence
Authors: Masrizal Masrizal , Fritiara Fritiara , Salsabila Ayu , Lukman Elsha , Mardhiyah Imalatul , Al Ghani Mardiah Putri
Published: June 2023

Tuberculosis is an infectious disease caused by the mycobacterium tuberculosis that remains a major global health problem with an estimated 10.4 million new cases of tuberculosis each year. Pulmonary Tuberculosis is a disease that has been around for a long time and is still a major problem in the health sector. Indonesia is the second largest contributor to the increase in tuberculosis cases globally.The meta study of this analysis aims to be a guide in decision making to  prevent the community from Tuberculosis transmission in the future.  Statistical methods in this Meta-Analysis study was combined the selected 6 articles of quantitative research from 47,474 by finding summary value using a review manager software version 5.4.1 and using a review of articles or journals that have been published for less than 5 years and are available in an online database such as Garuda, SINTA, PubMed, and Science Direct Meta analysis indicates that smoking behavior (95% ci : 1,93-6,62; P value < 0.0001), residential density (95% cl : 1,68-24,81; P value = 0.007), and humidity of 1,934 (95% ci : 1,02-2,43; P value = 0.004) increases the chances for tuberculosis. The study concluded that all variables such as smoking behaviour, residential density, and humidity increase the likelihood of tuberculosis. It has to recommended that  the decision makers on Health Office force to providing more media promotion and education to patients and their families about efforts to prevent and control TB disease is expected to prevent transmission of pulmonary tuberculosis transmission in Indonesia.

 

Keywords: Meta-analysis, Risk factors, Tuberculosis
Factors Related to Stunting Incidence in Toddlers Aged 24-59 Months in the Working Area of Kambang Community Health Center, Pesisir Selatan District
Authors: Ashari Rani , Basyir Vaulinne , Afriwardi Afriwardi , Mayetti Mayetti , Yusrawati Yusrawati , Desmawati Desmawati
Published: June 2023

Stunting is a major nutritional problem in Indonesia, even in the world particularly in developing countries. The purpose of the study was to find out the factors related to stunting in toddlers aged 24-59 months in the Pesisir Selatan District. This study is an analytical survey study with cross sectional design. This research will be conducted in the Kambang Health Center, Lengayang District, in July 2022–January 2023. The population in this study was all mothers who had toddlers aged 24-59 months who were in the Kambang Community Health Center working area in 2021 which numbered 1081 toddlers. Sample used in this study is 180 samples. The sampling technique used in this study is proportional stratified random sampling. Data collection tool using questionnaires. Analysis of the data in this study using Chi-Square test and use multiple logistical regression tests. The results showed that there was a significant relationship between the age of the mother during pregnancy  (p-value = 0.040), there was a relationship between the nutritional status of the mother (p-value = 0.003), there was a relationship between parity (p-value=0.034), there is a relationship between psychosocial parenting (p-value = 0.000), there is a relationship between environmental sanitation (p-value=0.000), there is no significant relationship between low birth weight (p-value = 0.071), there is a significant relationship between birth length (p-value = 0.016). Environmental sanitation is the most dominant factor in causing stunting. Environmental sanitation has a 6,512 times chance of causing stunting in toddlers aged 24-59 months in the working area of the Kambang Community Health Center, Pesisir Selatan District. It is recommended for health workers to provide supplements or supplements for pregnant women and toddlers for nutritional improvement and to educate them on nutritional knowledge.

Keywords:  Stunting, Mother Factors, Child Factors
Perbedaan Motivasi Mahasiswa Lulusan SMA dan SMK dalam Memilih Program Studi Pendidikan Kesejahteraan Keluarga (PKK)
Authors: Hasni Septi , Elida Elida
Published: June 2023

Motivasi dalam sebuah pemilihan sebuah Program Studi merupakan kondisi dimana dorongan kebutuhan yang secara cukup dirangsang untuk mengarahkan seseorang untuk mencari kepuasan . Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis perbedaan motivasi mahasiswa lulusan SMA dan SMK  memilih  Program Studi Pendidikan Kesejahteraan Keluarga (PKK), Departemen Ilmu Kesejahteraan Keluarga, Fakultas Pariwisata dan Perhotelan. Jenis penelitian ini adalah deskriptif komparatif. Populasi dalam penelitian ini adalah mahasiswa Prodi PKK, S1 Departemen IKK yang berjumlah 233 mahasiswa. Teknik pengambilan sampel menggunakan teknik Proporsional Random Sampling berjumlah 70 mahasiswa terdiri atas 34 mahasiswa lulusan SMK dan 36 mahasiswa lulusan SMK. Teknik pengumpulan data menggunakan kuisioner (Angket) melalui google form dengan menggunakan Skala Likert yang telah teruji validitas dan reliabilitasnya. Hasil penelitian menunjukan bahwa motivasi mahasiswa SMA dan SMK dalam memilih  Prodi PKK berada kategori sedang. Berdasarkan nilai rata-ratanya motivasi mahasiswa SMK dalam memilih  Prodi PKK lebih tinggi dibandingkan mahasiswa lulusan SMA. Berdasarkan analisis perbedaan terdapat perbedaan motivasi yang signifikan mahasiswa memilih Program Studi PKK antara mahasiswa lulusan SMA dan SMK dengan nilai Sig.(2-tailed) 0,015 < 0,05
Tecnologías cartográficas para la detección y monitorización de la especie Acacia dealbata en el municipio de Ribadavia (Ourense)
Authors: Álvarez Antelo Elena , Armesto González Julia
Published: June 2023

En este trabajo se estudia la caracterización fenológica de la especie exótica invasora (EEI) Acacia dealbata Link y su grado de invasión progresiva mediante un análisis temporal. Se establece una metodología empleando las siguientes herramientas: imágenes satelitales multiespectrales de fuentes cartográficas gratuitas y software basado en Sistemas de Información Geográfica.

Se ha conseguido desarrollar una secuencia de procesos para la detección y monitorización de la especie objeto de estudio que resulta eficaz a nivel municipio, y se considera de interés su aplicación en otras áreas de problemática semejante a la de Ribadavia para validar su efectividad.

Esta metodología pretende ser un avance para el planteamiento de posibles vías de mitigación, control y prevención de la especie Acacia dealbata Link.

Palabras clave: clasificación supervisada, especie exótica invasora, fuentes cartográficas gratuitas, teledetección.
Aydınlanma Karşıtlığı: 18. Yüzyılda Mimarlık ve Pitoresk
Authors: IŞIKER Figen
Published: June 2023

18. yüzyıl Aydınlanma dönemini inşa eden paradigmalar, birçok alanda eş zamanlı olarak gerçekleşir. Bu paradigmalar kavramların sınırlı içermelerle tartışıldığı, bilgi alanlarının disiplin rejimlerini üretmesine imkân vererek oldukça tanımlı bir çerçeve içinde ortaya konmalarına aracılık eder. Mimarlıkta epistemolojik söylemin inşası da benzer bir kavrayışla gerçekleşir. 18. yüzyılda arkeolojik alanların kazılmaya başlanması ve deniz aşırı seyahatlerin yapılması “başka” mimarlıkların farkına varılmasını sağlar. Ancak bu türden karşılaşmalar Antikite üzerine inşa edilen mimarlık bilgi alanının temellerini sarsar. Bu mimarlıkların belgelenmesi, durmadan çoğalan bilgi üretimini ve daha önce tartışılmamış pek çok konuyu kurumsal/kuramsal alanlarda da gündeme taşır. Verimli sayılabilecek hararetli tartışmalar yapılsa da bu karşılaşmalar kaçınılmaz olarak mimarlıkta paradokslar üreterek mevcut alışkanlıkları ve geleneksel söylemleri krize uğratır. Bu çalışma mimarlık içinde zaman-mekân paradoksu üretmiş ve bu nedenle anti-Aydınlanma olarak ifade edilebilecek durumlara neden olan örnekler etrafında şekillenir. Bu metinde yer alacak örnekler Alexander Pope, manzara bahçeleri ve folly özelinde bir tartışma yürütür. Sözkonusu örnekler Aydınlanma ideolojisi ile tutarlı bir alan olarak inşa edilmeye çalışılan mimarlığı, bütünüyle sterilize etmek için mimarlık tarihyazımında çok kısıtlı bir çerçevede konuşulmasına neden olur. Sözgelimi bu çalışmanın kuramsal altlığını oluşturan ve 18. yüzyıl mimarlık tarihyazımı içinde önemli bir yere sahip Pitoresk meselesi üzerine sayısız metin üretilmiş olsa da içindeki paradoksal durumlarla ilgili anlamlı tartışmalara pek rastlanmaz. Bu durum tesadüfi olmayacak biçimde mimarlığı belirli kurallar bütününün oluşturduğu bir alanda sınırlı bir bakışla görmeye neden olur. Oysa bu durumların da epistemolojisini anlamaya çalışmak, mimarlığı başka türlü konuşabilmenin yollarını aramak için oldukça önemlidir.
Differential expression of FGFR3 in cancer of the skin: malignant melanoma.
Authors: Mamoor Shahan
Published: June 2023

Skin cancer is diagnosed in nearly 1.5 million patients each year (1). While patients with basal and squamous cell carcinomas are provided with 5-year survival rates at nearly 100% and 90%, respectively, patients diagnosed with cutaneous melanoma (metastatic melanoma) are provided 5-year survival rates at 91.4% at stage I and 24.6% at stage IV (2-5). We mined published microarray datasets (6, 7) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with the deadliest type of skin cancer, malignant melanoma. We found significant differential expression of the gene encoding fibroblast growth factor receptor 3, FGFR3, when comparing melanoma tumor tissue from the human skin to the tissue of origin. FGFR3 mRNA was present at significantly higher quantities in melanoma tissues as compared to normal tissues from the skin. Analysis of human survival data revealed that expression of FGFR3 in melanoma tissues was correlated with overall survival in patients with malignant melanoma. FGFR3 expression changes may be important for the initiation or progression of malignant melanoma in humans.
The Impact of Lifestyle Choices on Cancer Prevention
Authors: Kalpoli Zumaira
Published: June 2023

The Impact of Lifestyle Choices on Cancer Prevention
How expired domain names of scientific journals can be a goldmine
Authors: Detective-Bard AI
Published: June 2023

The article is about how expired domain names of scientific journals can be a goldmine. Some people buy expired domain names of scientific journals and then create fake versions of the journals.
The Role of Genetic Testing in Personalized Cancer Treatment
Authors: bholpori werat
Published: June 2023

The Role of Genetic Testing in Personalized Cancer Treatment
HUBUNGAN KEHARMONISAN KELUARGA DENGAN MOTIVASI BELAJAR MAHASISWA KELAS 2021B PENDIDIKAN BAHASA DAN SASTRA INDONESIA UNIVERSITAS RIAU
Authors: Muliani Rahmi
Published: June 2023

Penelitian ini bertujuan untuk memahami dan menganalisis hubungan antara keharmonisan keluarga dengan motivasi belajar mahasiswa kelas 2021B Pendidikan Bahasa dan Sastra IndonesiaUniversitas Riau. Dengan pemahaman yang lebih baik tentang hubungan ini, pendidik dan orangtua dapat memainkan peran yang aktif dalam menciptakan lingkungan yang mendukung motivasi belajar mahasiswa. Penelitian ini menggunakan metode kuantitatif korelasional.Populasi dalam penelitian ini adalah mahasiswa kelas 2021B Pendidikan Bahasa dan Sastra Indonesia Universitas Riau. Pengambilan sampel dilakukan dengan teknik Simple Random Sampling. Simple Random Sampling, atau disebut juga Random Sampling. pengumpulan dataadalah dengan menyebarkan angket kepada masiswa sebagai sampel penelitian. Data dianalisis dengan menggunakan Uji Normalitas, Uji Linearitas, dan Uji Korelasi Product Moment.Berdasarkan uji Korelasi, nilai signifikansi 0,413> 0,05 maka hipotesis nol diterima. Artinya tidak terdapat hubungan antara keharmonisan keluarga dengan motivasi belajar pada mahasiswa kelas
The Role of Interoception in Age-Related Obesity: A Structural Equation Modelling Study.
Authors: Young Hayley Anne , Brennan Anthony
Published: June 2023

The obesity pandemic and its adverse effect on health and quality of life are well established. In younger populations interoception and aberrant eating styles contribute to overconsumption and being overweight. Although the incidence of obesity is higher in older individuals, they remain under-researched in the obesity literature. Therefore, the present study considered the role of general (interoceptive sensibility) and appetite specific (hunger drive and satiety responsiveness) interoception and obesogenic eating styles (food responsivity, emotional eating, enjoyment of eating) in the association between age and BMI. 1006 adults (aged 18 to 80) completed the Adult Eating Behaviour Questionnaire and the Interoceptive Attention and Accuracy scales. The data were analysed using Structural Equation Modelling (SEM) using AMOS. Despite being more overweight, older adults reported a lower interoceptive attention, hunger drive, emotional overeating, food responsivity, and enjoyment of food. In contrast, compared to younger adults, older adults reported a higher interoceptive accuracy, and a similar responsivity to satiety. Importantly, two indirect pathways positively mediated the link between age and BMI: (1) age → interoceptive attention → satiety responsivity → emotional eating → BMI and (2) age → interoceptive attention → satiety responsivity → food responsivity → BMI. However, a stronger antagonistic indirect pathway was also present: age → interoceptive attention → hunger drive → emotional eating → BMI. The present findings indicate that obesogenic interoceptive factors and eating styles commonly associated with being overweight in younger adults may not account for a higher BMI in older individuals. Interventions targeting obesity risk factors that have been mostly studied in young populations may be ineffective in older adults. More research is needed to determine the factors driving obesity in older populations.
Advancements in Targeted Therapies for Breast Cancer Treatment: Current Landscape and Future Perspectives
Authors: Kubarat Basneer
Published: June 2023

Advancements in Targeted Therapies for Breast Cancer Treatment: Current Landscape and Future Perspectives
Pengantar Bioteknologi
Authors: Erlidawati  , Sulastri
Published: June 2023

Buku ini memaparkan sejarah perkembangan bioteknologi dan ruang lingkupnya, prinsip-prinsip dasar bioteknologi, peranan mikroorganisme dalam bioteknologi, bioinformatika, aplikasi bioteknologi dalam bidang industry makanan dan minuman, bidang kesehatan, bidang pertanian dan kehutanan, bidang sumber dayaenergy, bidang lingkungan dan keanekaragaman hayati, resiko dan etika bioteknologi yang merupakan focus bahasan pengantar bioteknologi.
How AI can help combat paper mills
Authors: Combat-Bard AI
Published: June 2023

The article discusses the use of artificial intelligence (AI) to combat the problem of predatory journals. Predatory journals are journals that charge authors high fees to publish their research, often without providing any real peer review or editing services.
Mitigating the trade-off between verification and speculation in learning vowel harmony
Authors: Do Youngah , Van Hoey Thomas , Yu Bingzi
Published: June 2023

Phonological learning studies have provided mixed support for the substantive bias hypothesis. Some studies have shown better learning of phonetically grounded patterns, while others have reported opposite results. Based on evidence from learning science research, which shows that learners tend to attend to novel or unexpected items, we hypothesize that the inconsistent support for the substantive bias is due to learners’ tendency to direct their attention to phonetically “unexpected” or ungrounded patterns. We conducted two artificial language experiments involving vowel harmony and disharmony to observe the types of items learners tend to focus on. Our findings show that learners focused more on the items from which they could verify learned patterns, instead of being speculative. Contrary to our prediction, we found no significant difference in the choices of learning items between vowel harmony and disharmony conditions. However, our results demonstrate that the verification of learned items consistently facilitated the acquisition of vowel harmony, while this learning strategy did not always help with the acquisition of vowel disharmony. The differences found between the harmony and disharmony conditions suggest that strategic learning processes have a direct impact on learning harmony but not on learning disharmony.
Local social-ecological context explains seasonal rural-rural migration of the poorest in a rural community in southwestern Bangladesh.
Authors: Clech Lucie , Sierra Juan  Pablo , Mannan Muhammad  Abdul , Kabir Mollah M.  Shamsul , Barua Mrittika , Espinoza Jhan-Carlo , Ridde Valery
Published: June 2023

Bangladesh is one of the countries most affected by climate change. Internal migration is often presented as a response to environmental degradation in rural areas. Here, we hypothesise that climate-induced changes and adaptations impact local production and the local labour market, seasonally pushing out unskilled landless workers. We focus on different categories of livelihoods and their interactions to understand the local socio-ecological context for unskilled landless workers. We conducted fourteen semi-directed interviews and six focus group discussions with villagers in March-April 2022. We use a configurational approach considering changes>impacts> responses>impacts of responses to analyse our data for agricultural farmers, fish farmers, independent fishermen and unskilled workers. We conducted rainfall analysis on Chirps data for 1981-2021 to confront perception of changes to climate data.Villagers reported that waterlogging was the most significant change. Covid-19 lockdowns were cited as an aggravating factor. Most climate-induced changes began to occur gradually over the past 25 years. Climate data compared with emic perception confirm these results. We find that changes, particularly climate-induced changes, increase local inequalities. The shift in land use to fish farming, partly driven by the motivation to adapt to waterlogging and salinisation, increases the waterlogging problem locally. As a result, farms are submerged, production is lost, and fewer jobs are available locally. Smallholder farmers suffer more than wealthier farmers and have more difficulty covering the losses associated with these changes and the costs associated with adaptations. Fishermen are converting to unskilled work, and unskilled and landless workers migrate to other rural destinations for labour.
From interoception to control over the internal body: The ideomotor hypothesis of voluntary interoaction
Authors: Verschooren Sam , Gaebler Michael , Brass Marcel
Published: June 2023

When it comes to body movements in external space, people are experts in learning fine-grained voluntary somatomotor control, for example when manipulating tiny objects. Voluntarily controlling visceromotor actions in the internal body (e.g., decreasing heart rate), however, is far more difficult and requires dedicated training, for example in meditation or yoga. Not much is currently known about the learning mechanism underlying the acquisition of voluntary control over internal visceromotor actions (i.e., interoaction) or why it is so difficult compared to controlling our external somatomotor actions (i.e., exteroaction). We propose the ideomotor hypothesis of voluntary interoaction here, which asserts that voluntary extero- and interoactions are governed by the same general principle, namely the anticipation of sensory feedback. We apply this hypothesis to two techniques that can be used to acquire voluntary control over interoactions, i.e., autogenic training and biofeedback training. As the afferent signal we receive from interoaction (i.e., interoceptive signals from the internal body) is of lower sensory quality than the afferent signal we receive from exteroaction (i.e., exteroceptive signals from the external environment), this hypothesis explains why learning to control interoactions is more difficult. We propose ways in which to test predictions from this hypothesis and show its theoretical value by comparing it to other frameworks in the literature. We hope that this work motivates future empirical studies directly examining voluntary interoaction and its clinical applications, such as autogenic and biofeedback training, and mind-body practices more generally.
On the importance of severely testing deep learning models of cognition
Authors: Bowers Jeffrey S , Malhotra Gaurav , Adolfi Federico G , Dujmović Marin , Montero Milton Llera , Biscione Valerio , Puebla Guillermo , Hummel John , Heaton Rachel Flood
Published: June 2023

Researchers studying the correspondences between Deep Neural Networks (DNNs) and humans often give little consideration to severe testing when drawing conclusions from empirical findings, and this is impeding progress in building better models of minds. We first detail what we mean by severe testing and highlight how this is especially important when working with opaque models with many free parameters that may solve a given task in multiple different ways. Second, we provide multiple examples of researchers making strong claims regarding DNN-human similarities without engaging in severe testing of their hypotheses. Third, we consider why severe testing is undervalued. We provide evidence that part of the fault lies with the review process. There is now a widespread appreciation in many areas of science that a bias for publishing positive results (among other practices) is leading to a credibility crisis, but there seems less awareness of the problem here.
Qualität von Forschungsleistungen
Authors: Hamann Julian
Published: June 2023

The contribution proceeds from the observation that current discussions on research and funding policy increasingly conflate the concept 'research quality' with the concept of 'research performance'. After distinguishing the notions of 'quality' and 'performance', the first step of the contribution is devoted to central dimensions of 'research quality': plausibility, originality, scientific and social relevance. Broadly speaking, these four dimensions have authority across disciplinary cultures. The first step thus concludes with a discussion of notions of research quality that are rather discipline specific. In a second step, the contribution sheds light on central indicators of 'research performance': third-party funding, publications and citations. The contribution concludes with a discussion that relates the concepts of 'quality' and 'performance' by asking to what extent 'research performance' is actually indicative of 'research quality'.
Wavy Leading Edge (WLE) Influence on a Rectangular Wing Using an Unsteady Analysis Approach
Authors: Rohmawati Iis , Arai Hiroshi , Nurjannah Ika
Published: June 2023

A rectangular wing with Wavy Leading Edge (WLE) effect was investigated experimentally and numerically. This research was carried out with the NACA 0018 profile. The morphology of humpback whale flippers, which are blunt and rounded in a specific pattern, inspired the design of the WLE. The rectangular wing was explored in pitching motion with a reduced frequency of k = 0.25 and varied aspect ratios. Multiple aspect ratios (AR) of the rectangular wing have been evaluated to determine the best wing aspect ratio, notably 3.9, 5.1, and 7.9. Only at AR 3.9 and 5.1 does the WLE perform efficiently in both upstroke and downstroke motion. WLE has a sinusoidal function shape. The improvement of lift force was stronger during upstroke motion than during downstroke motion. The stall is minimized during the pitching motion of the WLE wing, according to the numerical simulation. This result could be applied to fin stabilizers or wind turbines.
Effect of sowing time and seeding rates on field germination and harvesting preservation of wintering peas in the southern part of the Rostov region
Authors: Vasilchenko S. A. , Metlina G. V. , Ashiev A. R.
Published: June 2023

The current paper has presented the study results of the elements of cultivation technology (sowing time, seeding rate) of wintering peas in the southern part of the Rostov region. Field trials were carried out during two agricultural years in 2019–2020 and 2020–2021. The objects of research were the varieties of wintering peas ‘Fokus’, ‘Faeton’, ‘Zimus’. The purpose of the research was to study the effect of sowing time and seeding rates on field germination and harvesting preservation of wintering peas in the conditions of the southern part of the Rostov region. The soil of the experimental plot was ordinary calcareous heavy loamy chernozem on loess-like loams. The content of humus in the arable layer was 3.36%, pH was 7.0, P2O5 was 24.4; K2O was 360 mg/kg of soil. The sowing time had an impact on field germination. On average, over the years of research, field germination in the 1st period ranged from 27.0 to 93.5 %, in the second from 33.6 to 91.0 %, in the third from 31.5 to 94.5 %. The share of the effect of the sowing time on field germination ranged from 9.4% for the variety ‘Faeton’ to 22.5 % for the variety ‘Fokus’. The harvesting preservation of wintering peas ranged from 93.8 % (‘Zimus’) to 94.8 % (‘Faeton’) in the first sowing period, in the second sowing period it ranged from 95.0 % (‘Faeton’) to 95.5 % (‘Fokus’), in the third, the harvesting preservation ranged from 94.7 % for the variety ‘Fokus’ to 95.6 % for the variety ‘Zimus’. The share of the effect of the sowing time on harvesting preservation ranged from 5.4 % for the variety ‘Zimus’ to 23.4 % for the variety ‘Fokus’. On average, over the years of study, the maximum field germination was observed for the variety ‘Faeton’ (93.5 %) at a seeding rate of 1.0 million germin. seeds/ha. The best preservation was identified for the variety ‘Faeton’ (96.5 %) at a seeding rate of 1.0 million germin. seeds/ha in the second sowing period.
Sowing time of winter crops in the Donbass due to weather and climate changes
Authors: Konoplya N. I. , Kurdyukova O. N.
Published: June 2023

The purpose of the current study was to clarify the optimal sowing time of wheat and winter barley after non-fallow forecrops (spring barley and sunflower) due to weather and climate changes. The trials were carried out during 2018–2022 on ordinary blackearth. The experiments, records and observations were carried out according to generally accepted methods. There has been established that at early sowing date (September 10), wheat and barley formed up to 5.4 tillering sprouts, from 2.4 to 6.2 nodal roots, plant height reached 22.1–27.9 cm with a plant weight of 174–223 g/m2, which indicated the overgrowth of plants. At a late sowing date (October 20), the tillering coefficient of wheat plants did not exceed 1.0–1.5, the number of nodal roots was 1.1–2.4, and the weight reached 32–58 g/m2.Barley plants at late sowing periods had significant developmental advantages compared to wheat. At the time of the termination of the autumn vegetation, they had an average of 1.5–2.0 sprouts and 2.5–3.1 nodal roots, and the above-ground mass was 2.0 times larger than that of wheat. In spring, winter barley plants grew and developed more intensively. Wheat productivity during early sowing date (10.09 and 20.09) was larger than that of barley by 7.5–27.0%. When sowing later, on the contrary, winter barley productivity was more on 7.0–14.8%. The optimal sowing time for winter wheat at which the maximum grain yield (4.17–4.32 t/ha) can be formed is the period from September 20 to October 1, and from 1 to 10 October for winter barley (4.37–4.48 t/ha).
Soulpepper 2022: Decolonizing Toronto Theatre
Authors: Shore Hanna
Published: June 2023

This research project, “Decolonizing Toronto Theatre,” examines how Soulpepper, a mainstream Toronto theatre company, and their collaboration with Native Earth Performing Arts are contributing to the equity, diversity, inclusion, and decolonization of Toronto theatre through their recent Indigenous productions: Kamloopa and Where the Blood Mixes. The author watched, read, and analyzed both plays to explore how these two productions transform and redefine the intellectual, political, and artistic conventions of Anglo-Canadian theatre. Her analyses of these plays are informed by the various texts centered around Canadian Indigenous history and Indigenous theatre. She also used an ethnographic approach by talking to people involved in both productions. She conducted interviews with the playwrights, the associate artistic director at Soulpepper, and some artists involved in both plays. These conversations with the people involved allowed her to understand these plays beyond their content: the inner workings of how a production comes to fruition. The conversations also allowed for a reflection on the similarities and differences between the creative approaches the artists involved took as well as the positive impacts these productions have had on Toronto theatre. Finally, by applying ethnographic findings and analyses of the plays, this piece compiles the analyses and research conducted over the course of the internship.
The Hierarchy on Its Side Becomes a Circle: The Directing Practices and Mentorship of Yvette Nolan
Authors: Peters Charlie
Published: June 2023

This article explores the directing practice of Algonquin and Irish theatre artist Yvette Nolan. Though Nolan is best known as a playwright, this article instead focuses on Nolan as “mentor to a generation of artists” and a significant contemporary theatre director whose interventions into inherited, colonial theatre practices warrant dissemination and discussion. The article explores her directing practice using three major themes: 1) values, process, and who is in the room; 2) food and joy and/as Ceremony; and, 3) vision and excellence. Working to situate hirself relationally as per Indigenous research practices, the non-Indigenous author uses original interviews, existing scholarship, and personal experiences collaborating with Nolan to inform this personal reflection on her practice.
“Visual Translation and the Amazing Broken Telephone Kaleidoscope”: A Dialogue
Authors: Germain Kat , Cripps Jody H. , Watkin Jessica , Stinson David
Published: June 2023

Kat Germain considers media accessibility strategies while translating signed music by Deaf artists, drawing on her experience as a visual translator/interpreter and audio describer for Blind and partially sighted audience members. Germain queries: What is the disparity between a Deaf artist’s (nonvocal) work and a Blind audience member’s experience of it? When does visual translation stop being a copy, and when does it become a work of art in its own right if the audience member’s only experience is the audible translation, an unavoidably a creative act? Along with Germain, the panel (Deaf scholar/artist, Blind scholar/creator/audience member, and a sound engineer) discusses aspects of ethics and aesthetics of accessibility in the arts.
Manejo general nutricional del paciente gran quemado adulto y sus complicaciones
Authors: Villalobos Mora Carlos , Vargas Vargas Nicole
Published: June 2023

Las quemaduras se dan cuando los tejidos blandos entran en contacto con una fuente de calor o energía, varían en su presentación y severidad. La morbilidad y la mortalidad se incrementan de acuerdo a la cantidad de superficie corporal quemada, mientras que la localización de las lesiones, la energía, y el tiempo de exposición contribuyen a la severidad. Los pacientes grandes quemados presentan alteraciones metabólicas muy significativas que repercuten negativamente en la morbilidad, la mortalidad y el tiempo de recuperación. El soporte nutricional aporta los nutrientes y los agentes terapéuticos necesarios para mantener el estado nutricional. El objetivo principal del soporte nutricional es aportar las distintas demandas corporales que son consecuencia del hipercatabolismo. El inicio del soporte nutricional temprano en los pacientes quemados, que tengan criterio para este, representa uno de los factores más efectivos en la regulación metabólica dada por las lesiones térmicas, manifestándose como una disminución de la respuesta catabólica y actualmente considerados como piedra angular en el manejo básico de los grandes quemados. Existen tres distintas vías de soporte nutricional, la oral, enteral o parenteral. La vía oral es la recomendada, si el paciente puede consumir el 60% de los requerimientos calóricos. Si el consumo es inadecuado, se debe considerar la nutrición enteral o parenteral. El paciente gran quemado es de manejo multidisciplinario. Las quemaduras que afectan más de 20% de la superficie corporal afectada requieren nutrición enteral temprana, ya que mejora la supervivencia y disminuye la estancia hospitalaria, así como las complicaciones tanto gastrointestinales como generales.
Variantes anatómicas del segmento anterior del polígono de Willis: relación con aneurismas cerebrales
Authors: Zamora-Chavarría Alejandro , Herrera-Guerra Camila , Quesada Navarro Franklin , Ballesteros Herrera Daniel
Published: June 2023

El polígono de Willis es una red vascular que aporta sangre al cerebro y a las estructuras circundantes. Una de sus principales funciones es mantener la irrigación a través de las anastomosis, cuando se presenta alguna condición que compromete el flujo de alguna de sus ramas. Está compuesto por las arterias cerebral anterior, comunicante anterior, carótida interna, cerebral posterior y comunicante posterior. Su conformación varía en la población. Más del 30-60% de las personas presentan una composición distinta a la habitual, siendo la hipoplasia de uno o más vasos la variante anatómica más común. Esta se define como la existencia de menos de 1 mm de calibre externo en la comunicante anterior y cerebral posterior, y los segmentos arteriales A1 de la cerebral anterior y P1 de la cerebral posterior. La arteria cerebral posterior es la que se encuentra hipoplásica con mayor frecuencia, seguida del segmento P1 de la cerebral posterior, el segmento A1 de la cerebral anterior y la comunicante anterior.

La formación de aneurismas intracraneales es más frecuente en la arteria comunicante anterior. Se han determinado como factores de riesgo para su aparición el predominio unilateral del tronco de la arteria cerebral anterior, la aplasia/hipoplasia del segmento A2, y la hipoplasia del segmento A1. Esta última variante constituye el principal factor riesgo para la ruptura de los aneurismas intracraneales de la arteria comunicante anterior, ya que aumenta el flujo sanguíneo en el lado opuesto y, con ello, provoca un incremento de la presión intramural que favorece el desarrollo del aneurisma.
Reacciones transfusionales agudas, complicación de cuidado en la práctica clínica
Authors: Arias Rojas Gilberth Andrés , Delgado Solano Valerie Fernanda , Navas Contreras Mariosby Gabriela
Published: June 2023

Las transfusiones sanguíneas son procedimientos realizados diariamente en todos los centros de salud alrededor del mundo, y las reacciones transfusionales agudas son una complicación grave y potencialmente mortal relacionada con estas. Las reacciones transfusionales agudas se definen como aquellas que ocurren en las primeras 24 horas, entre las más frecuentes se incluyen reacciones febriles no hemolíticas, reacciones alérgicas y anafilaxia, sobrecarga circulatoria, lesión pulmonar aguda y hemólisis. Las manifestaciones clínicas varían desde muy leves y autolimitadas, como fiebre, escalofríos, náuseas, alteraciones en presión arterial y frecuencia cardiaca; hasta otras más graves con compromiso cardiovascular, falla renal, alteraciones en la coagulación y hasta la muerte.

La comprensión de la fisiopatología, factores de riesgo y diferencias en la clínica permite la identificación temprana de la reacción, fundamental para minimizar la morbimortalidad y optimizar los resultados clínicos. La implementación de estrategias de mitigación y otras medidas preventivas permite reducir el riesgo de eventos adversos relacionados con la transfusión. Medidas como la selección adecuada de los donadores, la identificación precisa receptor y la vigilancia continua en aquellos pacientes con factores de riesgo como niños, adultos mayores, pacientes con problemas cardíacos, renales, historia de cáncer o de transfusiones a repetición. Este artículo revisa la bibliografía actual sobre las reacciones transfusionales agudas y proporciona información útil para la práctica clínica.