bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute Headache Management for Patients with Subarachnoid Hemorrhage: An International Survey of Healthcare Providers
Authors: Maciel Carolina B. , Barlow Brooke , Gobinathan Arravintha , Abu-Mowis Zaid , Peethala Mounika Mukherjee , Merck Lisa H. , Aspide Raffaele , Dickinson Katie , Miao Guanhong , Shan Guogen , Bilotta Federico , Morris Nicholas , Citerio Giuseppe , Busl Katharina M. , Lucke-Wold Brandon
Published: June 2022

Background: Severe headaches are common after subarachnoid hemorrhage (SAH). Guidelines recommend treatment with acetaminophen and opioids, but patient data show that headaches often persist despite multimodal treatment approaches. Considering an overall slim body of data for a common complaint affecting SAH patients during their intensive care stay, we set out to assess practice patterns in headache management among clinicians who treat patients with SAH.Methods: We conducted an international cross-sectional study through a 37-question web-based survey distributed to members of 5 professional societies relevant to intensive and neurocritical care from 11/2021-1/2022. Responses were characterized through descriptive analyses; Fisher’s exact test was used to test associations.Results: Of 516 responses, 329/497 (66%) were from North America and 121/497 (24%) from Europe. 379/435 (87%) reported headache as major management concern for SAH patients. Intensive-care-teams were primarily responsible for analgesia during hospitalization (249/435, 57%), while responsibility shifted to neurosurgery at discharge (233/501, 47%). Most used medications were acetaminophen (90%), opioids (66%), corticosteroids (28%) and antiseizure medications (28%). Opioids or medication combinations including opioids were most frequently perceived as most effective, by 169/433 (39%, predominantly intensivists), followed by corticosteroids or combinations with corticosteroids (96/433, 22%, predominantly neurologists). Of medications prescribed at discharge, acetaminophen was most common (303/381, 80%), followed by opioids (175/381 [46%]), and antiseizure medications (173/381, 45%). Opioids during hospitalization were significantly more prescribed by intensivists, by providers managing higher numbers of SAH patients, and in Europe. At discharge, opioids were more frequently prescribed in North America. 299/435 (69%) indicated no change in prescription practice of opioids with the opioid crisis. Additional differences in prescription patterns between continents and providers, and inpatient versus discharge were found. Conclusions: Post-SAH headache in the intensive care setting is a major clinical concern. Analgesia heavily relies on opioids both in utilization and in perception of efficacy, with no reported change in prescription patterns for opioids for most providers despite the significant drawbacks of opioids. Responsibility for analgesia shifts between hospitalization and discharge. International and provider-related differences are evident. Novel treatment strategies and alignment of prescription between providers are urgently needed.
Albumin mRNA and filamin-A are helpful for differentiating intrahepatic cholangiocarcinoma from extrahepatic origins
Authors: Chung Yeon Seung , Jeon Youngsic , Yoo Jeong Eun , Chung Taek , Rhee Hyungjin , Ryu Hyang Joo , Kim Hyunki , Park Young Nyun
Published: June 2022

Background: The differential diagnosis of intrahepatic cholangiocarcinomas (iCCAs) from metastatic adenocarcinomas from organs adjacent to the liver is difficult due to histopathological similarity and a lack of specific markers. This study evaluates the performance of albumin mRNA in situ hybridization (ISH) and immunohistochemistry (IHC) of filamin-A and cytokeratin 19 (CK19) for differential diagnosis.Methods: A total of 181 iCCAs and 116 adenocarcinomas from extrahepatic organs (30 gallbladder, 28 pancreas, and 58 stomach) were collected, and albumin ISH and IHC for filamin-A and CK19 were performed. The sensitivity, specificity, and the area under the curve (AUC) on the receiver operating characteristic (ROC) curve analysis of each marker were evaluated for the diagnosis of iCCA over extrahepatic adenocarcinoma.Results: Albumin ISH showed 23.2% sensitivity and 100% specificity for iCCAs, including both the small-duct and large-duct types. The expression of filamin-A and CK19 in albumin ISH-negative iCCAs was compared with that in extrahepatic adenocarcinomas. Filamin-A showed 71.1% sensitivity, 87.5% specificity, and 0.79 AUC on the ROC in small-duct-type iCCAs, whereas it had 27.5% sensitivity, 87.5% specificity, and 0.58 AUC on the ROC in large-duct-type iCCAs. CK19 showed 87.9% sensitivity, 59.4% specificity, and 0.74 AUC on the ROC in large-duct-type iCCAs, whereas it had 44.7% sensitivity, 59.4% specificity, and 0.52 AUC on the ROC in small-duct-type iCCAs.Conclusion: Albumin ISH and IHC for filamin-A and CK19 showed distinct expression patterns according to iCCA type. Albumin ISH positivity supports the possibility of iCCA, and filamin-A IHC is helpful for differentiating small-duct-type iCCA from extrahepatic adenocarcinomas.
“Respecting our patients’ choices”: Making the organizational decision to participate in voluntary assisted dying provision: Findings from semi-structured interviews with a rural community hospice board of management
Authors: Auret Kirsten , Pikora Terri J , Gersbach Kate , Donovan Robert J
Published: June 2022

Background
There is limited literature around how palliative care organizations determine the degree to which they will interface with voluntary assisted dying in jurisdictions where it is legal. The aim of this research was to describe the experience of the board of management of an Australian community-based hospice during their decision-making process around whether to support voluntary assisted dying in the facility, prior to full enactment of legislation.
Methods
Semi-structured interviews were conducted with seven of the nine board members. Interviews were audio-recorded and transcribed verbatim, and analysed using the qualitative content analysis method.
Results
The board members experienced a sense of journey in reaching an overall decision, which was to allow full participation in voluntary assisted dying provision for inpatients. Themes based on the journey motif included: starting from a personal view; moving to a hospice perspective; exploring if voluntary assisted dying can be part of end-of-life care; awareness and assessment of risks to the Hospice; arriving at a common platform to vote on; factors facilitating a safe decision-making journey; and personal impact of the journey.
Conclusions
The group highlighted several facilitators of a successful outcome including having adequate time, the availability of useful resources, sound board processes and a trusting culture. The study may provide support to other healthcare organisations as they face similar decisions triggered by legislative change.
Texture Based Superpixel Segmentation Algorithm for Hyperspectral Image Classification
Authors: Subudhi Subhashree , Patro Ramnarayan , Biswal Pradyut Kumar
Published: June 2022

Superpixel segmentation is a potential preprocessing tool that can simplify an image by creating semantic sub-regions of the image. This is quite effective in reducing the misclassification of isolated pixels. Image segmentation using superpixels has been successfully applied in the computer vision field. Recently, superpixel segmentation is being adopted into HSI processing domain also, due to its superior properties. In this work, for the accurate classification of the Hyperspectral Image, a texture-based superpixel segmentation algorithm is proposed. Local Binary Pattern (LBP) and Gabor filters are first incorporated to extract the local and global image texture information. Next, Simple Linear Iterative Clustering (SLIC) superpixel segmentation algorithm is applied over the extracted texture features and a superpixel segmentation map is obtained. Finally, majority voting strategy is performed between the superpixel segmentation map and the pixel-wise classification map to acquire the final classification map. For validating the effectiveness of the proposed algorithm, experiments were conducted on four popular HSI datasets, namely: Indian Pines, Pavia University, Houston 2013, and Houston 2018 datasets. Superior classification performance was observed by the proposed method in comparison to other state-of-the-art methods.
Smartphone usage before and after Covid-19: a comparative study based on objective recording of usage data
Authors: Chemnad Khansa , Alshakhsi Sameha , Almourad Mohamed Basel , Altuwairiqi Majid , Ali Raian
Published: June 2022

Most studies that claimed changes in smartphone usage during COVID-19 were based on self-reported usage data, e.g. collected through a questionnaire. These studies were also limited to reporting the overall smartphone usage, with no detailed investigation of distinct types of apps. The current study investigates smartphone usage before and after COVID-19. Our study uses a dataset from a smartphone app that objectively logs users' activities, including apps accessed and each app session's start and end time. These were collected during two periods: pre-COVID-19 (161 individuals with 77 females) and during COVID-19 (251 individuals with 159 females). We report on the top 15 apps used in both periods. Mann-Whitney U test was used for the inferential analysis. The results revealed that time spent on the smartphone has increased since COVID-19. Emerging adults were found to spend more time on the smartphone compared to adults during both periods. The time spent on social media apps has increased since COVID-19. Females were found to spend more time on social media than males. Females were also found to be more likely to launch social media apps than males. There has been an increase in the number of people who use gaming apps since the pandemic. Value: The use of objectively collected data is a methodological strength of our study. We draw parallels on the usage of smartphone with contexts similar to COVID-19 period, especially concerning limitation on social gathering, including working from home for extended periods.
Structural Behavior of Corroded Beams - Numerical and Analytical Approach
Authors: Marawan Ahmed. E. , Debaiky Ahmed. S. , Abdel-Kareem Ahmed. H.
Published: June 2022

To simulate corrosion deterioration on load carrying capacities, deflection an slip between concrete and steel for R.C. beams, 3-D F.E. model was considered by using ANSYS software. Several F.E. models were created to simulate different levels of corrosion. In these models, both concrete and steel were modeled as solid elements and stirrups were represented as link elements. To consider corrosion effects which can be represented by reduction in steel cross section and decrease in bond between concrete and steel, contact element between to bodies was created. Also, analytical calculations were driven to calculate load carrying capacities, deflection and slippage distance. The results of both models were acceptable within average error about 10%.
Caring Load and Family Caregivers’ Burden in China:The Mediating Effects of Social Support and Social Exclusion
Authors: Hu Hongwei , Xu Yang , Liu Hongting
Published: June 2022

Objective: Caring for the disabled elderly is a source of stress for family caregivers, and the lack of social support and the pressure of social exclusion might aggravate family caregiver burden. The purpose of this study was to examine the association between caring load and family caregivers’ burden, as well as the mediating effects of social support and social exclusion.Methods: Data used in this study derived from the nationally representative database of aged population in China, and 3125 households with family caregivers for the home-bound disabled elderly were eventually selected into this analysis. Regression methods and mediation analysis methods were employed in this study.Results: The results indicated that there was a significant positive association between caring load and the caregiver burden, and specifically, social support intensity (rather than social support breadth) and passive social exclusion (rather than active social exclusion) played partial mediating effects. Furthermore, the contributions of mediating effects of social support intensity and passive social exclusion were 13-15% and 27%-29%, respectively, and the total contribution of mediating effects was about 35%-38%.Conclusion: Family caregivers’ burden should be paid more attention in the large population with rapidly aging speed like China, and more guidance services as well as support should be provided to family caregivers. In addition, it is crucial to focus on the social support and social exclusion in community in the public policy innovation.
Tidal expiratory flow limitation detected with intra-breath oscillometry in obesity hypoventilation syndrome: effects of body position and positive airway pressure; a cross-sectional study
Authors: Baglyas Szabolcs , Valkó Luca , Móró Vivien , Podmaniczky Eszter , Czövek Dorottya , Makan Gergely , Gingl Zoltán , Gál János , Hantos Zoltán , Lorx András
Published: June 2022

Background Altered respiratory mechanics due to increased extrapulmonary mechanical load may be the key to understanding the profound effect of continuous positive airway pressure (CPAP) therapy in obesity hypoventilation syndrome (OHS). Methods We performed a cross-sectional study to assess intra-breath mechanical changes in an OHS population. 10 Hz intra-breath oscillometry and forced spirometry values were measured in the sitting and supine positions, followed by a supine oscillometry at different CPAP levels (none-5-10-15-20 cmH2O). We plotted intra-breath resistance (Rrs) and reactance (Xrs) values against flow and volume to analyse tidal changes in a more detailed manner.Results Thirty-five patients completed the study. Intra-breath reactance variables differed by body position (end-expiratory reactance: -1.85 (±1.89) hPa·s·L-1 vs -4.17 (±2.22) hPa·s·L-1, and by difference between end-expiratory and end-inspiratory reactance: -1.27 (±1.68) hPa·s·L-1 vs -3.56 (±2.02) hPa·s·L-1, sitting vs supine respectively, p<0.001). Temporal mapping displayed characteristic looping of Xrs against tidal volume and flow, suggesting tEFL. Augmented CPAP levels were associated with improved Xrs values and reduced loop areas, suggesting diminished tEFL (p<0.001). CPAP-induced expiratory glottal interference was observed in 60% of patients parallel with small airway mechanical changes affecting expiratory Rrs values. No correlation was found between forced spirometry values and intra-breath oscillometry variables. We also did not detect correlation between intra-breath oscillometry variables and body mass index (BMI), OHS staging or age.Conclusion tEFL is frequently present in patients with OHS during quiet breathing, worsening in the supine position. CPAP appears to counteract this effect, suggesting that tEFL is an important factor in the pathomechanism of respiratory impairment and a possible target for optimizing therapy. Trial Registration This study was approved by and registered at the ethics committee of Semmelweis University (SE TUKEB 239/2018)
Genome-wide dissection of Quan9311A breeding and application
Authors: Li Qianlong , Feng Qi , Wang Heqin , Kang Yunhai , Zhang Conghe , Du Ming , Zhang Yunhu , Wang Hui , Chen Jinjie , Han Bin , Fang Yu , Wang Ahong
Published: June 2022

Germplasm resource innovation is the key to variety development. Quan9311A is a three-line cytoplasmic male sterile (CMS) line of rice used for hybrid rice breeding based on the three-line system. It is the first CMS line that has been successfully cultivated with rice restoration materials and widely applied as a female parent line for hybrid breeding in China. The variety improvement of Quan9311A is based on an ingenious design. It was screened from the cross progeny of the three-line sterile line Zhong9A and the two-line restorer line 93 − 11, which are the core germplasms used to breed Quan9311A. According to phenotype, China breeders removed the restorability of 93 − 11, and cultivated Quan9311A: it combines the desirable agronomic traits of both 93 − 11 and Zhong9A, such as a moderate plant height, suitable heading date, and more tillers. In this study, genome-wide analysis was performed to investigate how Quan9311A was bred. RiceNavi analysis technology was used to dissect its functional genes associated with desirable agronomic traits based on whole-genome sequencing. The results show that rice breeders removed the fertility restorer gene Rf3 in 93 − 11 but retained the sterility gene WA352c of Zhong9A during the breeding process of Quan9311A. Not only are there many 93 − 11 chromosomal segments in the Quan9311A genome background but also multiple superior alleles of the parental 93 − 11 and Zhong9A lines are pyramided, conferring to Quan9311A excellent agronomic traits that were unavailable in earlier three-line sterile lines. We also found that Quanyou Simiao, a hybrid rice combination bred with Quan9311A as the female parent, harbors more superior alleles which could explain its high grain yield and wide adaptability. This study’s findings will promote the utilization of hybrid rice pairing groups and guide future breeding efforts. Meanwhile, it also provides fresh ideas for further promoting the closer integration of genomics with traditional breeding methods.
Characteristics and risk assessment of heavy metal pollution of farmlands and crops near Pb–Zn mine tailing ponds: a case study in Niujiaotang, China
Authors: Li Qinyuan , Han Zhiwei , Tian Yutong , Xiao Han , Yang Miao
Published: June 2022

To accurately evaluate the pollution and risk of heavy metals in crops and farmlands near mines, we determined the contents of Cr, Ni, Cu, As, Cd, Pb, and Zn in 10 farmland soil sampling sites and six crops (pak choi, rice, spring onion, radish, Chinese cabbage, Chrysanthemum coronarium) in an area near the Niujiaotang Pb–Zn mine in Duyun City, China. Four evaluation methods were compared, including the potential ecological hazard index, Nemeiro comprehensive pollution assessment, risk assessment code, and the ratio of secondary phase to primary phase methods. The average concentration of As, Cd, Pb, and Zn exceeded the soil environmental background levels in Niujiaotang and Guizhou Province. Cd exceeded the standard substantially, and Zn pollution accumulation was the most evident. Heavy metal contamination of crops was in the order pak choi > Chinese cabbage > spring onion > paddy > radish > Chrysanthemum coronarium, whereas heavy metal concentration in soils were in the order Zn > As > Cr > Cd > Ni > Pb. The levels of all heavy metals except Cu exceeded Chinese food hygiene standards. Carcinogenic and non-carcinogenic chemicals in crops present significant risks to adults and children. Risk evaluation considering the morphological contents of heavy metals rather than their total concentration was more accurate for environmental quality assessment of agricultural soils.
Prevalence and Immediate Outcomes of Low Birth Weight Neonates Born of Preeclamptic Women at Moi Teaching & Referral Hospital, Kenya
Authors: Sigei Linah , Nyaga Emily Muthoni , Milimo Benson
Published: June 2022

Background: Pre-eclampsia has been linked to poor neonatal outcomes such as; stillbirth, low birth weight (LBW), prematurity and neonatal morbidities. Objective: To determine the prevalence of LBW and immediate (within 24 hours) birth outcomes of LBW neonates born of pre-eclamptic women at Moi Teaching & Referral Hospital, Kenya. Methods: A descriptive cross-sectional study was conducted among 364 participants (346 singletons and 18 twins). A structured interviewer administered questionnaire was used to gather data on birth weight and neonatal outcomes. Data was cleaned, coded and entered into SPSS version 22 for analysis. Descriptive statistics were computed for the prevalence of LBW and immediate birth outcomes. Results: The prevalence of LBW was 180(49.45%). Notably, of the LBW neonates; 162(90%) were alive while 18(10%) were stillbirths. Immediate morbidities were; birth asphyxia 51(28.73%), neonatal jaundice 38(21%), hypothermia 18(7.90%) and neonatal sepsis 1(0.68%). Of the neonates that were alive; 107(59.18%) were admitted to level II nursery care, 53(29.53%) were rooming in with their mothers and 2(1.36%) had died. Conclusion: The prevalence of LBW and its associated mortality/morbidity among neonates born of pre-eclamptic women is alarmingly high and the nursery admissions are majorly due to birth asphyxia.
Surgical Correction of Total Anomalous Pulmonary Venous Return in an Adult Patient
Authors: Bae Yohan , Jang Woo Sung , Song Kyungsub
Published: June 2022

Total anomalous pulmonary venous return (TAPVR) is a rare congenital heart disease. Most TAPVRs require surgical corrections in the neonatal period and survival to adulthood without surgical correction is extremely rare. Most untreated patients with large atrial septal defects and no pulmonary venous obstruction have pulmonary vascular damage from pulmonary over circulation. It is rare for TAPVR to be reported in adulthood, and we report TAPVR in a 44-year-old patient treated successfully with surgical correction. A snowman-shaped heart, including cardiomegaly and an increase in pulmonary blood flow, was seen in the chest X-ray, and A large-sized (around 3 cm) atrial septal defect (ASD) with dilated right atrium, right ventricle, and pulmonary artery was detected on echocardiography. Heart computed tomography was performed for further evaluation, and supra-cardiac type TAPVR without any obstructive lesion was identified. The patient is doing well, and sinus rhythm and mild mitral valve regurgitation have remained during 2.5 years of outpatient follow-up.
Impact of antihistamines use on immune checkpoint inhibitors response in advanced cancer patients
Authors: mocan eda eylemer , Mocan eda Eylemer , Yekedüz Emre , Karataş Göktürk , Yazgan Satı Coşkun , Köksoy Elif Berna , Şenler Filiz Çay , Utkan Güngör , Demirkazık Ahmet , Akbulut Hakan , Ürün Yüksel
Published: June 2022

Background
Histamine and H1 receptor play a crucial role in the tumor microenvironment. Preclinical data showed that concomitant use of antihistamines and immune checkpoint inhibitors (ICIs) may increase the effect of ICIs. This study aimed to evaluate impact of antihistamines on oncological outcomes of ICIs.
Patients and Methods
This retrospective study was conducted in a tertiary cancer center. Advanced cancer patients treated with ICIs were included in this study.
Results
A total of 133 patients receiving ICIs in the metastatic setting were included. Melanoma (33.1%) was the most common tumor type. The most common ICI was nivolumab (63.2%). Fifty-five (38.4%) patients received antihistamines concomitantly with ICIs. The most common antihistamine was pheniramine (85.5%). The median progression-free survival (PFS) (8.2 vs. 5.1 months, log-rank p = 0.016) and overall survival (OS) (16.2 vs. 7.7 months, log-rank p = 0.002) were longer in patients receiving antihistamines concomitantly with ICIs. In multivariate analysis, PFS (Hazard Ratio (HR) = 0.63, 95% CI:0.40–0.98, p = 0.042) and OS (HR = 0.49, 95% CI:0.29–0.81, p = 0.006) were also better in those patients after adjusting for confounding factors, such as performance status, bone or liver metastasis, and concurrent chemotherapy.
Conclusion
This study suggested that antihistamines may enhance the efficacy of ICIs in patients with advanced cancer. If validated in prospective trials, antihistamines and ICIs combinations might be new options to improve oncological outcomes.
Highly specialized Breast Centers did not experience delay of care during COVID-19 pandemic in Italy: the Senonetwork experience
Authors: Losurdo Agnese , Lisa Andrea , Tomatis Mariano , Ponti Antonio , Montemezzi Stefania , Bonzano Elisabetta , Fortunato Lucio
Published: June 2022

Aim of the studyThe study aims to evaluate the performance of selected, high-volume, highly specialized, Italian Breast Centers at the time of COVID-19 pandemic (year 2020), compared to pre-pandemic time (year 2019), highlighting differences in terms of clinical presentation of breast cancer (BC) and therapeutic strategies. MethodsPatients’ data were provided by the Senonetwork data warehouse Senonet. In order to examine changes in the surgical and oncological management of BC patients during different phases of COVID-19 pandemic, we took advantage of a selection quality indicators (QIs). We performed the analyses in two time-frames, from July to September (Jul-Sep) (2019 versus 2020) and from October to December (Oct-Dec) (2019 versus 2020). ResultsOur analysis did not show any statistically significant difference in terms of diagnosis, surgical, oncological and radiation therapy procedures between the two trimesters 2019 and 2020. Nevertheless, we observed statistically significant differences, favoring 2020, when analyzing time-to surgery and time-to radiotherapy. On the other hand, we observed a significant reduction of neoadjuvant chemotherapy and we did not recollect any data on a major use of neoadjuvant endocrine therapy. ConclusionsIn Italian Breast Centers, partners of Senonetwork, we could not observe any treatment-delay or change in standard clinical practice for BC care during the 2020 pandemic year, compared to 2019 pre-pandemic year. This finding is in contrast with the globally reported decrease in the performance of the Italian Breast Centers due to the COVID-19 pandemic, and has to be linked to the sharp selection of Senonetwork Breast Centers.
Totally laparoscopic total gastrectomy with linear anastomosis versus laparoscopic-assisted total gastrectomy in gastric cancer：a single-center experience with meta-analysis
Authors: Wang Weizhi , Lv Jialun , Li Fengyuan , Fang Lang , Li Bowen , Li Zheng , Wang Sen , Xu Jianghao , Liu Hongda , He Zhongyuan , Li Qingya , Xie Li , Wang Linjun , Zhang Diancai , Xu Hao , Yang Li , Xu Zekuan
Published: June 2022

Objective
Laparoscopic-assisted total gastrectomy (LATG) is the most common methods of gastrectomy for gastric cancer (GC). However, totally laparoscopic total gastrectomy (TLTG) is uncommon because reconstruction is difficult, especially for the intracorporeal esophagojejunostomy. In this study, we compared short-term oncologic outcomes in TLTG group with linear anastomosis and LATG group.
Methods
The retrospective cross-sectional study was conducted. The clinic-pathological data of 108 patients underwent TLTG and 153 patients underwent LATG who were admitted to the First Affiliated Hospital of Nanjing Medical University between May 2016 and October 2019 were collected. The clinicopathological characteristics and surgical outcomes before and after propensity score matching (PSM) were compared between the two groups. Furthermore, a systematic review and meta-analysis were conducted.
Results
Besides the estimated blood loss(P < 0.001) and the length of incision(P < 0.001) in TLTG group was less than those in LATG group, no other differences were found between the two groups in operative time (P = 0.993), the number of harvested lymph nodes (P = 0.181), the time of first flatus(P = 0.076), start of liquid diet (P = 0.240), start of soft diet (P = 0.147), the time of removing drainage (P = 0.725), postoperative hospital stay (P = 0.688)and postoperative morbidity (P = 1.000) after PSM. The meta-analysis also demonstrated no significant differences in above surgical outcomes among the groups, although the number of harvested lymph nodes was higher and estimated blood loss was lower in the TLTG group than that in the LATG group.
Conclusions
TLTG for GC is feasible and safe. However, the further validation of high-quality randomized controlled trial is still needed.
Multi-objective allocation optimization of soil conservation measures under data uncertainty
Authors: Hildemann Moritz , Pebesma Edzer , Verstegen Judith Anne
Published: June 2022

Many regions worldwide face soil loss rates that endanger future food supply. The installation of soil and water conservation measures reduces soil loss rates but comes with high labor costs. A multi-objective optimization allows considering both soil loss rates and labor costs, but required spatial data contains uncertainties. Yet, spatial data uncertainty has not been considered in research for allocating soil and water conservation measures. We aim to overcome that research gap by optimizing conservation measure allocations despite spatial data uncertainties. We propose a multi-objective genetic algorithm that creates optimal solutions that indicate which watersheds should be conserved. Stochastic objective values are computed from uncertain soil and precipitation variables to evaluate and compare solutions. The study is conducted in three rural areas in Ethiopia. The highest soil loss rate uncertainties result in objective values ranging up to 14%. The associated yield loss ranges with soil loss rates under uncertainties are comparable to reported yield loss risks from droughts. The uncertainty of labor requirement objective values is localised to less then 5% of the area in all three study areas. However, ranges in labor requirement estimations become up to 15 labor days per hectare in areas where labor requirements are uncertain. Upon further analysis of common characteristics and patterns in optimal solutions, we also conclude that the results can be used to define a temporal order for planning and implementing conservation measures.
Dual-Polarized MIMO Antenna System for 5G Indoor base Station Applications
Authors: Surendra Loya , khan Habihulla
Published: June 2022

In this paper a dual-polarized multiple-input multiple-output (MIMO) antenna system for fifth-generation (5G) indoor base station applications resonating at 3.5 GHz has been proposed. The initial design is a conventional patch antenna, and characteristic mode analysis (CMA) is used to determine its dual-polarized characteristics. Both orthogonal modes are excited using the full-wave approach with a 50 Ohm dual-port coaxial feed line, and operated at 3.5 GHz. The non-contact feed method is used to improve isolation between ports. Inserting an air gap between the antenna substrate and the ground metal sheet improves gain and bandwidth. Further 2x2 MIMO antenna with 8-port is designed on low cost FR4 dielectric material with 120*120*5.17 mm3 compact volume. The MIMO antenna’s performance are examined by simulation and experimental. For the proposed MIMO, high isolation, high efficiency, and appropriate gain-level characteristics have been obtained. Furthermore, throughout the whole band of interest, the calculated total active reflection coefficient (TARC) and envelope correlation coefficient (ECC) of the antenna components are very low, indicating that the proposed multi-antenna systems are capable of enormous MIMO and diversity applications. Furthermore, the antenna avoids the use of complex feeding mechanisms such as baluns or directional couplers.
Menstrual Hygiene Management Challenges Among In-School Deaf Adolescents in Ghana
Authors: Mprah Wisdom Kwadwo , sackey Emmanuel , Dourinaah Juventus
Published: June 2022

Background
Whiles challenges associated with menstrual hygiene management among adolescents are universal, some sub-populations, such as deaf girls, have peculiar challenges that requires special attention. Although there have been numerous studies on menstrual hygiene management among adolescents in the school setting in Ghana, the experiences of students with disabilities, particularly, deaf girls have not attracted adequate scholarly attention.
Objective
The objective of the study was to generate new empirical evidence on menstrual hygiene management challenges of deaf adolescent girls in the special schools for the deaf in Ghana. The goal was to obtain data that could be used to improve menstrual hygiene practices among the target population, and, to bridge the gap in the existing literature regarding menstrual hygiene management experiences of in-school adolescent deaf girls in Ghana.
Method
This study adopted a mixed method approach to investigate the menstrual hygiene management challenges of in-school deaf adolescent girls in Ghana. A total of 152 participants comprising 118 schoolgirls, 15 boys, seven school heads, six teachers, and six school housemothers from seven special schools were involved in the study. Since the students were living in a boarding house or a residential school setting, in accordance with the ethical principles of the Ghana Education Service, informed consent was sought from the Special Education Division of the Ghana Education Service and the management of the schools.
Results
The findings identified five challenges facing the girls. These are inadequate access to sanitary pads, inappropriate school Water, Sanitation, and Hygiene (WASH) facilities, health related problems, negative attitude of male colleagues, and academic related challenges.
Conclusion
The findings indicate that the quality of WASH facilities in the schools require improvement. We recommend that access to sanitary kits for underprivileged girls in the schools should be made a priority issue of the school hygiene programme of the Ghana Education Service, boys and male teachers should be included in all menstrual hygiene management awareness programs, whiles the capacity of school housemothers on menstrual hygiene management should be enhanced.
Influence of perception on service satisfaction of community health centers among older adults or their families in Chongqing, China: a path analysis
Authors: Luo Jing , Sha Zhihui , Wu Tiantian , Liu Chen , Wang Chenghu , Luo Jing
Published: June 2022

Background
Community health centers (CHCs) have now served as the primary healthcare facilities especially for older adults in China. There is a paucity in current literature about public satisfaction with CHC services from the perspective of subjective perception. We aimed to identify the perception factors influencing satisfaction with CHC services among older adults or their families, and explore the influence paths, in Banan district of Chongqing, China.
Methods
A sample survey was conducted among 879 households in 32 communities in Banan district in March 2019 to obtain the basic data. The hypothetical service satisfaction model, the degree of the influence of each perception factor on final satisfaction, and influence paths were analyzed using the Smart PLS 3.0 software.
Results
A total of 800 households with older adult(s) aged 60 years and over were included in the study. Service expectation (-0.191), perceived quality (0.508) and perceived value (0.441) were the three direct factors influencing the satisfaction with CHC services. Both perceived quality and service expectation could indirectly affect public satisfaction by way of influencing perceived value (0.224 and -0.087, respectively).
Conclusions
Service expectation, service quality and value recognition are the main factors affecting satisfaction with CHC services. Service quality and accessibility should be improved along with the incremental construction of rational service expectation towards CHCs. Policy and financial inputs and the introduction of well-trained health providers are of great importance. Furthermore, equal access to CHC services should be gradually promoted especially for older adults.
Inhalations with surfactant-BL in the late respiratory phase of COVID-19 in the patient with a severe course of the disease
Authors: Kudinova S. N. , Pasynkova T. A. , Аkimenko N. N.
Published: June 2022

The patient with severe viral-bacterial pneumonia and veriﬁed COVID-19 was successfully treated with surfactant therapy in the late respiratory phase of the disease, surfactant therapy was used to reduce the degree of hypoxemia and accelerate the weaning from non-invasive mechanical ventilation (NIMV). The native surfactant was administered with inhalations at the dose of 75 mg 2times a day on the 5th day of NIMV since SpO2 values persisted to be 92-93% and did not improve. Positive changes were observed after 4 inhalations: SpO2 reached 95% and then remained within the range of 94-97% with FiO2 90%. In total, the patient received 10 inhalations, then she was gradually transferred to breathing through an oronasal mask with humidiﬁed oxygen.
Prevalence and treatment tactics of nonspeciﬁc urinary tract infection in tuberculosis patients
Authors: Rashidov Z. R. , Azimov S. I.
Published: June 2022

The objective: to study prevalence and evaluate the eﬃcacy of therapy and prevention of nonspeciﬁc urinary tract infection (NUTI) in tuberculosis patients as well as the possibility of combining them with anti-tuberculosis therapy.

Subjects and Methods. 936 patients with various localizations of tuberculosis at the age from 18 to 96 years old were examined. Men made 447 (47.8%), and women – 489 (52.2%). NUTI was diagnosed based on the following criteria: the presence of typical symptoms, leukocyturia and bacteriuria detected by urine microscopy, positive results of urine culture for nonspeciﬁc bacterial population, and negative urine tests for tuberculous mycobacteria.

Results. The prevalence of NUTI among tuberculosis patients made 174 (18.6%) out of 936 patients, it was found among all forms of TB but most frequently in urogenital tuberculosis (74.1%). Prophylactic treatment tactic (antibacterial therapy and the herbal formulation of Kanefron N) was oﬀered. Treatment eﬃcacy made 94.6%, while patients received anti-tuberculosis therapy, and the combination of drugs caused no adverse reaction in any patient. When choosing a therapeutic tactic, it is necessary to take into account the presence of structural and functional changes in the urinary tract which reduce treatment eﬃcacy.
Physical representations for scattering amplitudes and the wavefunction of the universe
Authors: Benincasa Paolo , Torres Bobadilla William J.
Published: June 2022

The way we organise perturbation theory is of fundamental importance both for computing the observables of relevance and for extracting fundamental physics out of them. If on one hand the different ways in which the perturbative observables can be written make manifest different features (e.g. symmetries as well as principles such as unitarity, causality and locality), on the other hand precisely demanding that some concrete features are manifest lead to different ways of organising perturbation theory. In the context of flat-space scattering amplitudes, a number of them are already known and exploited, while much less is known for cosmological observables. In the present work, we show how to systematically write down both the wavefunction of the universe and the flat-space scattering amplitudes, in such a way that they manifestly show physical poles only. We make use of the invariant definition of such observables in terms of cosmological polytopes and their scattering facet. In particular, we show that such representations correspond to triangulations of such objects through hyperplanes identified by the intersection of their facets outside of them. All possible triangulations of this type generate the different representations. This allows us to provide a general proof for the conjectured all-loop causal representation of scattering amplitudes. Importantly, all such representations can be viewed as making explicit a subset of compatible singularities, and our construction provides a way to extend Steinmann relations to higher codimension singularities for both the flat-space scattering amplitudes and the cosmological wavefunction.
MONEY POLICY IMPLEMENTATION: ISSUES AND PARADOXES
Authors:   PhD Student in Economy and Management, Fsjes Souissi Um5 Rabat, Cedoc, Larcepem., Hakik Idriss
Published: June 2022

Monetary policy is conducted through transmission channels which are by definition channels through which monetary variables influence real economic variables, notably the liquidity effect, which is shown by the repercussions of a change in the money supply on global demand, and the interest rate effect, which has an impact on the cost of capital, thus affecting the spending behaviour of agents through income effects and their choice of assets through substitution effects. To the extent that price and exchange rate expectations modulate the economic and financial behaviour of agents, monetary policy also tries to influence these variables via announcement effects. The effectiveness of these effects remains conditioned by the credibility of monetary policy and the confidence of agents in this policy. This paper attempts to explain the objectives of monetary policy and their paradoxical management. The main internal objective of monetary policy is the fight against inflation through demand and inflation through income. Subsequently, the external objective of exchange rate stability. Monetary policy may, therefore, be faced with a dilemma, in that the emergence of conflicts between internal and external objectives calls for contradictory and transitional measures.
El phubbing y las relaciones de pareja adulta
Authors: Rendón Vélez y Leidy Julieth
Published: June 2022

Objetivo: comprender cuáles son los efectos generados por el Phubbing en las relaciones de pareja adulta. Materiales: la investigación es cualitativa y fenomenológica, para ello se trabaja con las historias de vida recolectadas por medio de una entrevista a profundidad, la misma se diseñó teniendo en cuenta las categorías de análisis. Población: para el trabajo de campo se contó con cinco personas, adultos jóvenes con edades entre 25 a 40 años. Metodología: la presente investigación comprendida en el periodo de febrero hasta noviembre de 2020 se realizó bajo un enfoque cualitativo con diseño fenomenológico, el cual lleva a una comprensión e interpretación en amplitud del fenómeno, enfocado desde la realidad subjetiva de los informantes, es un enfoque dinámico donde las hipótesis y preguntas pueden manifestarse en cualquier momento (Hernández Sampieri et al., 2014). Resultados: se reconoce que este fenómeno es significativamente interferente en las relaciones de pareja, fomentando sentimientos de abandono e incluso en algunos casos de desconfianza. Conclusión: el consumo de las nuevas tecnologías permite apreciaciones encontradas, en tanto se encuentran posturasa favor y en contra; en todo caso el fenómeno resulta conflictivo cuando no se tiene un uso racional y mediático, llegando a interponerse como una barrera comunicativa.
Reflexiones sobre el aprendizaje colaborativo desde la experiencia de estudiantes de Trabajo Social de la Universidad Católica Luis Amigó
Authors: Correa Guisao Natalia Andrea , Toro Serna Astrid Johana Johana
Published: June 2022

El artículo desarrolla una reflexión conceptual sobre el aprendizaje colaborativo, en relación con la mirada crítica de la experiencia de los estudiantes del programa de Trabajo Social a distancia de la Universidad Católica Luis Amigó. Si bien este concepto es transversal en muchos ámbitos de la vida, es una característica fundamental en el aprendizaje a distancia; por ello, el artículo desarrolla, en primer lugar, las características del aprendizaje colaborativo, seguidamente se plantean los aspectos significativos del aprendizaje colaborativo en este programa, lo que posibilita una reflexión de esta estrategia de enseñanza-aprendizaje en los procesos de educación contemporáneos.
Dificultades del aprendizaje en el déficit de atención e hiperactividad en preescolares: una revisión exploratoria de literatura
Authors: Álvarez García Adriana Marcela , Botero Carvajal Alejandro
Published: June 2022

Antecedentes: las dificultades del aprendizaje son la causa más común por la que niños en edad escolar reciben educación especial, sin embargo, la etiología de las dificultades del aprendizaje aún es desconocida. Por ello, se quiere determinar si una posible etiología de las dificultades de aprendizaje puede ser el trastorno de déficit de atención e hiperactividad, debido a que este último es uno de los trastornos más prevalentes en el contexto educativo. Por tal razón, el propósito del presente estudio es la revisión de literatura para determinar qué proporción de preescolares que reciben un diagnóstico de déficit de atención e hiperactividad puede esperar tener dificultades en el aprendizaje. Metodología: revisión exploratoria de literatura para identificar toda la bibliografía relevante en las bases de datos Scopus, Science Direct, PubMed y Google Scholar, relacionada con preescolares entre 2 y 5 años, que reciben diagnóstico de déficit de atención e hiperactividad y que evalúen dificultades del aprendizaje. Los tipos de artículos buscados fueron: ensayos clínicos, estudios de cohortes, estudios de casos y controles, porque permiten comprender la relación entre las dificultades del aprendizaje y los pacientes diagnosticados con déficit de atención e hiperactividad (TDAH). La estrategia de búsqueda se representa en el diagrama de flujo PRISMA 2009; la revisión tuvo en cuenta el modelo SPIDER. Resultados: no se encontraron estudios con las evidencias requeridas a nivel metodológico, pero sí estudios observacionales. 4 de los 6 artículos señalan que el TDAH afecta negativamente el aprendizaje; los 2 restantes no fueron concluyentes, debido a que los síntomas del TDAH pueden confundirse con comportamientos normales de la edad preescolar. Conclusiones: el TDAH en preescolares requiere diseños metodológicos que permitan calidad del dato para evaluar la proporción de niños entre 2 y 5 años que desarrollará una dificultad de aprendizaje. Así como la estandarización de un proceso diagnóstico del TDAH en edad preescolar.
Modelos epistemológicos en la consolidación de la psicología social
Authors: Orjuela Salazar Leydi Carolina
Published: June 2022

La psicología social se ha constituido en referencia necesaria a la hora de comprender los fenómenos socioculturales de la actualidad. Al acercarse a esta disciplina, es conveniente reconocer grosso modo algunas corrientes de pensamiento que han ejercido una notable influencia. Desde el Medioevo, el concepto de alma abría un panorama inédito que más adelante sería vinculado con el objeto de estudio de la psicología; más adelante, el método científico ofrecía la posibilidad de analizar la psique humana desde una perspectiva más positivista, que, aunque seguía atendiendo al ejercicio introspectivo, ya no pretendía comprender y/o definir el alma, pero sí los procesos psicológicos básicos entre los que se incluía la dimensión sociocultural del ser humano. Se van perfilando progresivamente dos enfoques: el de la psicología social psicológica que parte de la práctica experimental de Wilhelm Wundt y de su propuesta de la Völkerpsychologie, y el de la psicología social sociológica que atiende no tanto a los aspectos psíquicos de la socialización humana, sino al tejido relacional que ocurre desde prácticas y contextos específicos. Este acercamiento permite diferenciar los principales enfoques que han inspirado el objeto de estudio y los modos de intervención propios de la psicología social.
El sentido de la violencia y el desplazamiento
Authors: Castaño Suárez Marisol
Published: June 2022

La teoría expuesta en el presente texto se relaciona con los sentimientos de las personas víctimas del desplazamiento forzado; además del sometimiento al ser parte de una estructura sociocultural que vulnera su dignidad e identidad, obligándolo a permanecer oculto y en silencio porque el miedo no le ofrece alternativas. Dado lo anterior se mencionan elementos afines con el sentido del sufrimiento y su relación con el significado y significantes de la violencia y el desplazamiento, señalando transformaciones del sentido de ambos fenómenos socioculturales a partir de la implicación psicosocial, esgrimiendo reflexiones que surgen de algunas prácticas investigativas y de intervención en una situación concreta en tiempo, lugar y espacio.
Cuidar del otro. Palabra, alter y la salud mental en tiempos de pandemia
Authors: Osorio Sánchez Yeny Leydy
Published: June 2022

Este texto presenta una reflexión acerca de la función de la palabra como acción de cuidado del otro durante la pandemia actual. Se contrastan dos dimensiones: la afectación del discurso y del sujeto político durante el confinamiento y las formas en las que la palabratomó fuerza para contribuir a la generación de vínculo y al cuidado intersubjetivo.