bluuebunny/crossref_metadata_2025 huggingface dataset:
Sociodemographic Factors and Survival of Infants With Congenital Heart Defects
Authors: Pace Nelson D. , Oster Matthew E. , Forestieri Nina E. , Enright Dianne , Knight Jessica , Meyer Robert E.
Published: August 2018

OBJECTIVES:

To examine the first-year survival of infants with congenital heart defects (CHDs) and investigate the potential role of socioeconomic and demographic factors on survival.

METHODS:

Subjects included 15 533 infants with CHDs born between 2004 and 2013 ascertained by the NC Birth Defects Monitoring Program. We classified CHDs into the following 3 groups: critical univentricular (n = 575), critical biventricular (n = 1494), and noncritical biventricular (n = 13 345). We determined vital status and age at death through linkage to state vital records and used geocoded maternal residence at birth to obtain census information for study subjects. We calculated Kaplan–Meier survival estimates by maternal and infant characteristics and derived hazard ratios from Cox proportional hazard models for selected exposures.

RESULTS:

Among all infants with CHDs, there were 1289 deaths (8.3%) in the first year. Among infants with univentricular defects, 61.6% (95% confidence interval [CI]: 57.7%–65.7%) survived. Survival among infants with univentricular defects was considerably better for those whose fathers were ≥35 years old (71.6%; 95% CI: 63.8%–80.3%) compared with those whose fathers were younger (59.7%; 95% CI: 54.6%–65.2%). Factors associated with survival among infants with any biventricular defect included maternal education, race and/or ethnicity, marital status, and delivery at a heart center. The hazard of infant mortality was greatest among non-Hispanic African American mothers.

CONCLUSIONS:

Survival among infants with critical univentricular CHDs was less variable across sociodemographic categories compared with survival among infants with biventricular CHDs. Sociodemographic differences in survival among infants with less severe CHDs reinforces the importance of ensuring culturally effective pediatric care for at-risk infants and their families.
Penerapan Model Pembelajaran Kooperatif dengan Strategi Make A Match untuk Meningkatkan Kemampuan Komunikasi Matematika Siswa
Authors: Nurani Sujana Laeli Dwi , Juariah Juariah , Karso Karso , Kariadinata Rahayu
Published: August 2018

Komunikasi di dalam proses belajar sangat diperlukan karena komunikasi merupakan sesuatu yang utama dalam mengajar, menilai dalam pembelajaran matematika serta memudahkan dalam menyelesaikan permasalahan. komunikasi matematik mencakup beberapa hal yaitu kemampuan menulis, membaca, diskusi, evaluasi, dan berwacana.  Disamping itu yang perlu diperhatikan adalah model pembelajaran yang diterapkan guna menghadapi era globalisasi. Untuk meningkatkan hasil belajar siswa salah satu model yang dapat digunakan dalam pembelajaran adalah Make a Match. Make a Match atau mencari pasangan merupakan salah satu alternatif yang dapat diterapkan kepada siswa
Penerapan Teknik Ikonik terhadap Kemampuan Pemahaman Matematika Siswa pada Pembelajaran Matematika Pokok Bahasan Pecahan
Authors: Zahid Ahmad , Susilawati Wati , Jihad Asep , Maryono Iyon
Published: August 2018

Penelitian ini bertujuan untuk mengetahui kesuksesan siswa dalam belajar matematika yang dipengaruhi oleh cara guru menyampaikan materi pelajarannya. Seorang pengajar harus mencari dan memilih metode yang tepat untuk setiap topik yang kita berikan agar siswa berpartisipasi aktif tetapi pengajaran tetap efektif dan efisien. Kemampuan guru dalam menguasai materi dan menerapkan model pembelajaran merupakan salah satu faktor yang mempengaruhi keberhasilan guru dalam proses belajar-mengajar. Salah satu teknik yang dapat digunakan sebagai alternatif penyampaian materi adalah teknik ikonik. Teknik ikonik adalah penyampaian konsep matematika dengan perantaraan gambar yang pada akhirnya siswa menemukan sendiri konsep yang dipelajari dengan perantaraan gambar tersebut. penelitian ini dilakukan dengan tujuan untuk mengetahui kemampuan pemahaman matematik siswa, dengan pembelajaran menggunakan Teknik Ikonik. Metode yang digunakan dalam penelitian ini adalah penelitian tindakan kelas (Classroom Action Research) dengan subjek penelitian kelas VII SMP Negeri 1 Pangatikan Kabupaten Garut yang terdiri dari 21 siswa laki-laki dan 13 siswa perempuan. Adapun hasil yang diperoleh adalah (a) aktivitas guru selama proses pembelajaran selalu berpijak pada tahap-tahap teknik ikonik yang disesuai dengan indikator aktivitas guru, aktivitas belajar siswa selama proses pembelajaran dikategorikan baik,
ACTIVITY OF ORBIGNYA PHALERATA AND EUTERPE EDULES IN THE PREVENTION AND TREATMENT OF PEPTIC ULCER IN RATS
Authors: TORRES Orlando Jorge Martins , SANTOS Orlando José dos , MOURA Roberto Soares de , SERRA Humberto Oliveira , RAMOS Vanisse Portela , MELO Syomara Pereira da Costa , LOUREIRO Carlos Manoel Bulcão
Published: August 2018

ABSTRACT Background: Peptic ulcer is considered a public health problem associated with loss of quality of life. Does not exist optimal therapeutic regimen. The search for alternative treatments using foods or plants that may assist in gastric protection may become marked in this population because of their easy access and low cost. Aim: To study the antiulcerogenic activity of extracts of Orbignya phalerata (babaçu) and Euterpe edules (juçara) in Wistar rats after induction of peptic ulcer, compared with Omeprazole. Method: Forty Wistar rats were distributed into four groups: group I, II, III, IV (10 rats each) subjected to extract of Orbignya phalerata, Euterpe edules, Omeprazole and ethanol, respectively. Each group of 10 rats was divided into subgroups of five for prophylaxis and therapeutic study. Results: The pre-treatment with juçara extract has provided a significant protection against peptic ulcer induced by ethanol. In the prophylactic subgroup, Omeprazole resulted in protection. In addition to protection against peptic ulcer, inflammation and neocapillarization were also variables with a statistical significance in the prophylaxis subgroups using omeprazole and juçara. In the therapeutic subgroup, omeprazole, juçara and babaçu were statistically different as for protection against the presence of inflammation and the healing of ulcers. Conclusion: The extracts of juçara and babaçu behaved as the omeprazole, evidencing the therapeutic activity of these extracts.
PREVALENCE OF BACTERIOBILIA IN PATIENTS UNDERGOING ELECTIVE COLECYSTECTOMY
Authors: OLIVEIRA1 Rafael Soares de , SILVA Paula da , QUEIROZ Carlos Alfredo Salci , TERRA-JÚNIOR Juverson Alves , CREMA Eduardo
Published: August 2018

ABSTRACT Background: Cholelithiasis is one of the diseases with greater surgical indication. Currently, laparoscopic cholecystectomy is the gold standard in the treatment of cholelithiasis. Aim: To analyze the culture of bile from patients with cholelithiasis, mainly in the occurrence of brown and mixed stones. Methods: Was carried out a prospective study with 246 cases with biliary lithiasis who underwent elective laparoscopic cholecystectomy. Bile culture was performed in all. During anesthetic induction the patients received a single dose of intravenous cefazolin 1 g. At the end of the surgery, the gallbladder was punctured, its contents extracted and immediately placed in a sterile 20 ml propylene flask and promptly sent to bacterioscopy with Maconkey and blood agars. Incubation at 37° C for 24 h was carried out. A protocol was elaborated to include the main factors potentially related to cholelithiasis and the possible presence of associated bacterial infection. Results: Of the 246 patients, 201 had negative bile culture and 45 positive. Of the 45 patients with bacteriobilia, 34 had growth of a single type of bacterium in bile culture and 11 more than one. Conclusions: It was observed a relationship between bacteriobilia and age, suggesting that age is a risk factor for bacteriobilia. The use of antibiotic prophylaxis in the elderly is therefore recommended.
Rice Seed Production Under Conditions of Salinity Stres
Authors: Harter Fabio Schaun , Harter Leticia dos Santos Holbig , Meneghello Geri Eduardo
Published: August 2018

ABSTRACT: In the present study, the objective was to evaluate the production and quality of rice seeds of four cultivars under conditions of saline stress caused by irrigation water. The work was carried out at the EliseuMaciel Agronomy College of the Universidade Federal de Pelotas, with four rice cultivars, IRGA 417, Avaxi CL, Inov CL and IAS 12-9 (Formosa). In the experiment, the following saline concentrations were used: 0; 12.5; 25; 37.5; 50; 75 and 100mM. After completing the crop cycle, the following agronomic characteristics were evaluated in each of the plants: number of panicles, total weight of panicles, percentage of full seeds, percentage of seedlings and weight of a thousand seeds. The physiological quality of the seeds harvested from the plants maintained under conditions of salinity stress was evaluated by germination and first count tests. Saline stress reduced the productivity and physiological quality of rice seeds, with different responses from the four cultivars used.
Tolerance of apple rootstocks to short-term waterlogging
Authors: Marchioretto Lucas De Ross , Rossi Andrea De , Amaral Leonardo Oliboni do , Ribeiro Ana Maria Alves de Souza
Published: August 2018

ABSTRACT: Until few years ago there were limited options of apple rootstocks commercially available for Brazilian growers; although, new series of Geneva® rootstocks introduced recently present desirable features such as vigor control and wider lateral branch angle. On the main apple producing regions of Brazil, intermittent rainfall eventually occurs and waterlogged condition is frequent especially in high clay oxisols; in addition, little is known about the tolerance of rootstocks M.9, Marubakaido/M.9 interstock, G.202, G.213 and G.814 to waterlogging. Thus, the objective of this experiment was to evaluate the tolerance of these rootstocks to short-term waterlogging on root and aerial parameters. Potted ‘Maxi Gala’ apple plants were kept under 48 hours of waterlogging weekly throughout 19 weeks to be compared with a normal hydric condition control. The evaluated variables were: leaf, stem and root dry matter, number and length of new root emission, and number of leaves, mean leaf size and chlorophyll content. Rootstocks G.202, G.814 and Marubakaido/M.9 interstock presented more tolerance to waterlogging, and the main defense mechanism was the emission of new adventitious roots.
Microbiological quality of honey from stingless bee, jandaíra (Melipona subnitida), from the semiarid region of Brazil
Authors: Pinheiro Carolina de Gouveia Mendes da Escóssia , Abrantes Maria Rociene , Silva Rodrigo Otávio Silveira , Oliveira Junior Carlos Augusto , Lobato Francisco Carlos Faria , Silva Jean Berg Alves da
Published: August 2018

ABSTRACT: The aim of this study was to evaluate the presence of microorganisms in honey produced by the stingless bee (SB) jandaíra (Melipona subnitida) from the semiarid region of Brazil. Thirty-five samples were analyzed and all of them were positive for mesophilic bacteria, coliforms at 45°C, fungi, and yeast. Staphylococcus spp. were identified in 85.7%, while Bacillus spp. were detected in 34.3% of honey samples. DNAs of Clostridium perfringens and C. botulinum were detected in 40% and 2.8% of the samples, respectively. Salmonella spp. and C. difficile were not detected. The present research revealed a great diversity of microorganisms in honey produced by jandaíra.
Monoammonium phosphate coated with polymers and magnesium for coffee plants
Authors: Guelfi Douglas Ramos , Chagas Wantuir Filipe Teixeira , Lacerda Jordana Reis , Chagas Rafael Mattioli Rezende , Souza Taylor Lima de , Andrade André Baldansi
Published: August 2018

ABSTRACT The coating of phosphate fertilizer granules with polymers and magnesium (Mg) is a technology that can improve phosphorus (P) use efficiency and mitigate problems of low Mg supply in coffee crops. The objective of this work was to evaluate the growth and nutrition characteristics of coffee seedlings and the agronomic efficiency (AE) of monoammonium phosphate (MAP) coated with anionic polymers and Mg in comparison with other phosphate fertilizer technologies. The experiment was carried out in a greenhouse in 20 L pots. Two five-month-old coffee seedlings were transplanted into each pot. The experimental design was completely randomized with three replicates. The following treatments, applied at a dose corresponding to 20 g pot-1 of P2O5, were carried out: MAP; MAP coated with anionic polymers (Policote Phós®); MAP coated with anionic polymers+Mg (Policote Phós_Mg®); Top-Phós®; and Agrocote®. A control (without P) was prepared. Plant height; leaf area; dry mass of leaves, stems, and roots; total dry mass; shoot/root ratio; specific leaf weight; P and Mg content in plants and their availability in the soil after cultivation and efficiency indicesof the phosphate fertilization treatment were evaluated. The recovery of applied P and the agronomic efficiency of phosphate fertilizers was found to increase in the following order: MAP = Top-Phós® = Agrocote®<MAP+Policote Phós® = MAP+Policote Phós_Mg®. The coating of the MAP+Policote Phós_Mg® granules increased growth, the content and accumulation of P and Mg in coffee seedlings, the availability of these nutrients in the soil after cultivation and the agronomic efficiency of phosphate fertilization.
Imagem corporal de adolescentes do sexo feminino e sua associação à composição corporal e ao comportamento sedentário
Authors: Morais Núbia de Souza de , Miranda Valter Paulo Neves , Priore Silvia Eloiza
Published: August 2018

Resumo O objetivo deste artigo é avaliar a imagem corporal e sua associação à composição corporal, indicadores antropométricos e comportamento sedentário de adolescentes do sexo feminino. Estudo transversal com adolescentes do sexo feminino de Viçosa, MG. A imagem corporal foi avaliada por meio do Body Shape Questionnaire (BSQ) e pela Escala de Silhuetas. O percentual de gordura (%GC) e outros parâmetros antropométricos foram aferidos. O comportamento sedentário (CS) foi avaliado a partir da soma do tempo de tela (TT) e do tempo de celular (TC). A amostra foi composta por 274 adolescentes, a maioria com IMC adequado (81,6%), porém, 53,9% apresentaram o % GC elevado. Mais da metade das adolescentes apresentaram o CS elevado, 68,2% com o TT e 54,7% com o TC acima de 2h. A insatisfação corporal manifestou-se em 45,7%, e 50,2% desejaram uma silhueta diferente da atual. O perímetro da cintura (PC) (OR = 11,94, IC = 2,744 – 51,728) e a relação cintura-estatura (RCE) (OR = 10,535, IC = 3,109 – 35,698) foram as medidas mais associadas à insatisfação corporal. Todas as medidas de composição corporal apresentaram associação significativa com a insatisfação corporal, sendo o PC e o RCE os fatores mais condicionantes. O CS mostrou-se elevado, no entanto, não se associou com a avaliação negativa da imagem corporal.
Transtorno mental comum em mulheres adultas: identificando os segmentos mais vulneráveis
Authors: Senicato Caroline , Azevedo Renata Cruz Soares de , Barros Marilisa Berti de Azevedo
Published: August 2018

Resumo O objetivo deste estudo foi avaliar os fatores socioeconômicos e demográficos, os comportamentos e as morbidades associados ao transtorno mental comum em mulheres adultas. Trata-se de um estudo transversal de base populacional com amostra por conglomerados. Foram analisadas 848 mulheres por inquérito domiciliar realizado em Campinas, em 2008/2009. Foi usado o instrumento Self-Reporting Questionnare (SRQ-20) para avaliar o transtorno mental comum. Foram estimadas razões de prevalências por meio de regressão múltipla de Poisson em modelo hierárquico de três etapas, considerando as ponderações relativas ao desenho amostral. A prevalência de transtorno mental comum foi de 18,7%. O modelo hierárquico evidenciou que mulheres mais velhas, com baixa escolaridade, donas de casa, separadas ou viúvas, que não consumiam frutas/verduras/legumes diariamente, dormiam seis ou menos horas por noite, apresentavam várias doenças crônicas e problemas de saúde e com relato de algum tipo de violência foram mais vulneráveis ao transtorno mental comum e, por isso, devem ser tratadas com prioridade pelos serviços de saúde. Diagnosticar precocemente mulheres com transtorno mental comum, bem como acompanhá-las e tratá-las, contribuem para reduzir os impactos na qualidade de vida feminina.
Determinantes do baixo peso ao nascer em filhos de adolescentes: uma análise hierarquizada
Authors: Belfort Gabriella Pinto , Santos Marta Maria Antonieta de Souza , Pessoa Lidiane da Silva , Dias Juliana Rebelo , Heidelmann Sonaly Petronilho , Saunders Cláudia
Published: August 2018

Resumo Objetivou-se identificar os determinantes do baixo peso ao nascer - BPN, em filhos de adolescentes por meio de abordagem hierarquizada. Estudo transversal com 751 adolescentes atendidas em maternidade pública do Rio de Janeiro. Foram analisados dados sociodemográficos, da assistência pré-natal, condições biológicas e obstétricas maternas. Os possíveis determinantes do BPN foram identificados na análise bivariada e a seguir foram testados modelos de regressão logística hierarquizada, considerando o escalonamento hierarquizado em níveis distal, intermediário e proximal. Permaneceram no modelo as variáveis com valor de p < 0,05 em cada nível de análise e estimou-se as odds ratio (OR) ajustadas e intervalos de confiança (IC) de 95%. A prevalência de BPN foi de 10%. Os determinantes do BPN foram: nível distal - a não aceitação da gravidez (OR = 10,19; IC 95% = 1,09-39,53); nível intermediário - ter menos de seis consultas de pré-natal (OR = 4,29; IC 95% = 1,55-11,83), não ter assistência nutricional padronizada (OR = 3,18; IC 95% = 1,18-8,55); nível proximal – parto prematuro (OR = 10,19; IC 95% = 2,12-49,01). Os determinantes do BPN foram características maternas, da assistência pré-natal e condições ao nascer e, dentre estes fatores, temos características sociais modificáveis.
As ações de educação alimentar e nutricional e o nutricionista no âmbito do Programa Nacional de Alimentação Escolar
Authors: Silva Simoni Urbano da , Monego Estelamaris Tronco , Sousa Lucilene Maria de , Almeida Géssica Mercia de
Published: August 2018

Resumo O Programa Nacional de Alimentação Escolar (PNAE) preconiza a promoção de práticas alimentares saudáveis por meio da oferta de refeições juntamente com ações de educação alimentar e nutricional (EAN). O objetivo deste trabalho foi identificar as ações de EAN no PNAE e sua relação com o perfil do nutricionista. Estudo transversal analítico, realizado em municípios de Goiás, Brasil. Dados coletados por telefone, sendo a associação entre a variável desfecho (realização de EAN) e as de exposição (população escolar e atuação do nutricionista) feita por teste qui-quadrado de Pearson, nível de significância de 5,0%. Foram incluídos 214 (87%) municípios, dos quais 91,1% promovem EAN, com frequência predominantemente semestral (25,3% nas escolas e 23,2% nas creches). A presença do nutricionista mostrou-se associada à EAN (p = 0,001). Ações de EAN são executadas na maioria dos municípios, entretanto com baixa frequência. A associação encontrada indica a relevância da presença do nutricionista, em condições que atendam à legislação, possibilitando o cumprimento de suas atribuições, conforme definido pelo Marco Legal do PNAE e do Conselho Federal de Nutricionistas.
Permanência no mercado de trabalho e satisfação com a vida na velhice
Authors: Ribeiro Pricila Cristina Correa , Almada Daniele Soares Queiroz , Souto Jéssica Faria , Lourenço Roberto Alves
Published: August 2018

Resumo O envelhecimento da população é uma tendência mundial e chamou a atenção para as políticas de incentivo à vida produtiva e de adiamento da aposentadoria. Assim, cabe ampliar a compreensão dos efeitos do trabalho sobre os indicadores de saúde e bem-estar na velhice. O objetivo deste estudo foi verificar a associação da permanência no mercado de trabalho com fatores sociodemográficos, clínicos e de satisfação com a vida em idosos. Utilizou-se a base de dados do Estudo FIBRA-RJ que inclui idosos (idade > 65 anos) clientes de uma operadora de saúde, residentes na zona norte do município do Rio de Janeiro. Dentre os 626 participantes, 82 (13,1%) mantinham atividade de trabalho remunerado. Os resultados da regressão logística múltipla mostraram que as chances de permanecer trabalhando eram maiores para homens; para aqueles com 9 anos ou mais de estudos; com alta renda; sem condições clínicas crônicas incapacitantes e aqueles com maior satisfação com a vida. Este estudo confirma a associação das atividades de trabalho na velhice com melhores condições sociais e de saúde física. Além disso, observou-se que a manutenção das atividades de trabalho estava associada com a maior satisfação com a vida independente das características socioeconômicas e clínicas na velhice.
Utilização de Medicinas Alternativas e Complementares na atenção primária à saúde de Florianópolis/SC, Brasil: percepção de usuários
Authors: Faqueti Amanda , Tesser Charles Dalcanale
Published: August 2018

Resumo Apresenta-se análise parcial dos resultados de pesquisa que investigou as percepções de usuários sobre o uso institucional de Medicinas Alternativas e Complementares (MAC) nos centros de saúde de Florianópolis. Realizaram-se entrevistas semiestruturadas com usuários tratados com MAC nos locais com maiores ofertas, usando como referencial teórico-metodológico a teoria fundamentada em dados. Na sua maioria, o uso de MAC era proposto pelos profissionais da atenção básica (operadores do cuidado biomédico), inicialmente de forma alternativa e preferencial à biomedicina, e houve comum preferência dos entrevistados por essa forma de uso, devido aos menores efeitos colaterais atribuídos às MAC. Usuários referiram diálogo aumentado com os profissionais devido à negociação sobre as forma de tratamentos. Emergiu a hipótese de que as MAC podem ser um tratamento alternativo inicial em parte significativa dos casos, ficando o convencional como retaguarda para uso posterior se necessário, ou complementar ou único em outras situações. Isso permite esboçar um fluxo ampliado da presença das MAC na atenção primária à saúde. Novas pesquisas e experiências institucionais são necessárias para investigação dessa hipótese, que amplifica o uso das MAC numa ‘ecologia de cuidados institucionais’.
Tendências e padrões espaço-temporais da mortalidade relacionada à hanseníase no Estado da Bahia, Nordeste do Brasil, 1999-2014
Authors: Souza Eliana Amorim de , Boigny Reagan Nzundu , Oliveira Héllen Xavier , Oliveira Maria Leide Wand-Del-Rey de , Heukelbach Jorg , Alencar Carlos Henrique , Martins-Melo Francisco Rogerlândio , Ramos Júnior Alberto Novaes
Published: August 2018

Resumo Introdução A hanseníase é uma condição negligenciada, com alta carga de morbimortalidade, especialmente em áreas mais desfavoráveis. O objetivo deste estudo foi analisar as tendências e os padrões espaço-temporais da mortalidade relacionada à hanseníase no estado da Bahia, 1999-2014. Objetivo Analisar tendências e padrões espaço-temporais da mortalidade relacionada à hanseníase no Estado da Bahia de 1999 a 2014. Método Estudo de base populacional com dados secundários de mortalidade. Incluíram-se todos os óbitos em que a hanseníase foi mencionada como causa de morte. Resultados Foram registrados 1.152.262 óbitos, dos quais a hanseníase foi identificada em 481 (0,04%) casos, resultando em coeficiente bruto médio anual de mortalidade de 0,21 óbito/100 mil habitantes (intervalo de confiança [IC] de 95%: 0,13-0,29). Hanseníase não especificada (87,73%, ou 422/481) e complicações da hanseníase (6,44%, ou 31/481) foram as formas clínicas mais comumente mencionadas. O risco de óbito relacionado à hanseníase foi maior entre os homens (risco relativo [RR]: 2,38; IC 95%: 0,19-0,46), em idosos (RR: 74,79; IC 95%: 9,57-582,20) e na região oeste do Estado (RR: 4,08; IC 95%: 2,33-7,15). A mortalidade apresentou tendência temporal de aumento significativo no período ( Average Annual Percentual Change [AAPC] 7,3; IC 95%: 4,5 a 10,3), assim como a mortalidade proporcional (AAPC 5,3; IC 95%: 2,2 a 8,3). Conclusões A hanseníase representa uma causa negligenciada de óbito no Estado da Bahia. Apresenta tendências espaço-temporais desiguais nas regiões de saúde, com riscos associados, principalmente, à população masculina e idosa.
Efeitos de programas de reabilitação multidisciplinar no tratamento de pacientes com doença de Alzheimer: uma revisão sistemática
Authors: Madureira Bruna Guimarães , Pereira Maria Geralda , Avelino Patrick Roberto , Costa Henrique Silveira , Menezes Kênia Kiefer Parreiras de
Published: August 2018

Resumo Introdução A Doença de Alzheimer (DA) é caracterizada por perda das funções cognitivas de forma progressiva, como falhas na memória, aprendizagem e linguagem, que tendem a se agravar com o avanço da doença. As ações multidisciplinares no paciente com DA têm como objetivo interferir positivamente no processo saúde-doença, por meio de uma abordagem integral aos indivíduos e familiares, intervindo com ações voltadas à realidade na qual estão inseridos. Objetivo Realizar uma revisão sistemática sobre os efeitos da reabilitação multidisciplinar em pacientes com Doença de Alzheimer (DA). Método Foram realizadas buscas nas bases MEDLINE, LILACS, PEDro, CINAHL e Web of Science , sem restrição de data ou de idioma de publicação. Os artigos foram avaliados pelo título, pelo resumo e, posteriormente, pelo texto completo, por dois autores independentes. A qualidade metodológica dos estudos experimentais selecionados foi avaliada de acordo com a escala PEDro. Resultados Foram incluídos cinco estudos, de qualidade metodológica moderada (5,4 na escala PEDro), que evidenciaram que um programa multidisciplinar pode ser eficaz no tratamento de pacientes com DA, com melhoras significativas, principalmente, em sintomas neuropsiquiátricos, depressão e qualidade de vida. Para as demais medidas de desfecho investigadas, devido à presença de poucos estudos que encontraram efeitos positivos (nível de estresse, ansiedade, independência, atividades) ou de resultados conflitantes (cognição), não é possível determinar a eficácia dessa intervenção. Conclusão Esta revisão sistemática evidenciou que um programa multidisciplinar pode ser eficaz no tratamento de pacientes com DA, com melhoras significativas, principalmente, em sintomas neuropsiquiátricos, depressão e qualidade de vida. No entanto, os resultados para cognição, nível de ansiedade, estresse, independência e realização de atividades não foram significativos ou foram conflitantes.
Mineral and bromatological assessment and determination of the antioxidant capacity and bioactive compounds in native Amazon fruits
Authors: Becker Magda Márcia , Mandaji Carolina Marques , Catanante Gaëlle , Marty Jean-Louis , Nunes Gilvanda Silva
Published: August 2018

Abstract The proximate compositions, mineral contents, antioxidant capacity and bioactive compounds of 7 native Amazon fruits were chemically evaluated. The majority of the fruits showed high moisture contents (> 63.02%), and ash, total crude protein and total carbohydrate contents in the ranges of 0.22–2.07%, 0.17–2.44% and 7.17–41.71%, respectively. High levels of total lipids were found in uxi (23.25%) and monguba (18.67%). A wide range of mineral contents was detected and the highest levels were found in the samples of monguba seeds (Ca, Cu, Mg, and Zn), uxi pulp (Fe, and Mn) and pajurá pulp (Na). All the fruits showed antioxidant capacity, but the pajurá revealed the highest potential, statistically similar to that of acerola (p < 0.05). The highest vitamin C contents were found in bacuri and cupuaçu and the highest phenolic compound contents in monguba and pajurá fruits, but flavonoids were only detected in pajurá. A statistical correlation between the Na content and antioxidant capacity was also observed. Based on the results obtained, the fruits analyzed are suitable for use in the human diet, in the food and cosmetics industries as well as in pharmaceutical compositions.
Sistema de baixo custo para determinação da permeabilidade de CO2 em filmes plásticos
Authors: Carmelo Luis Gustavo Paulino , Calbo Adonai Gimenez , Correa Daniel Souza , Ferreira Marcos David
Published: August 2018

Resumo O objetivo deste trabalho foi desenvolver um método simples, de baixo custo e eficaz para avaliação da permeabilidade de filmes plásticos utilizados como materiais de embalagem para alimentos. Para isto, foram projetadas e construídas câmaras de permeação que permitem a troca gasosa através de um filme plástico, com área conhecida, e a medição da permeabilidade específica ao CO2 de cada filme. Para tanto, foram avaliados filmes de polietileno de baixa densidade (PEBD) e de policloreto de vinila (PVC). Os resultados demonstram correspondência com os testes realizados em equipamentos comerciais de análise da permeabilidade, em concordância com os valores apresentados por literatura específica. O método apresentado demonstrou eficiência nas análises de filmes poliméricos, podendo ser utilizado como uma ferramenta na determinação da permeabilidade de filmes a diferentes gases, como O2, CO2 e etileno. Além disto, o equipamento é de simples operação e os parâmetros, como umidade relativa, temperatura e fluxo, são facilmente ajustáveis.
Propriedades antioxidantes do açaí (Euterpe oleracea ) na síndrome metabólica
Authors: Cedrim Paula Cavalcante Amélio Silva , Barros Elenita Marinho Albuquerque , Nascimento Ticiano Gomes do
Published: August 2018

Resumo Alimentos ricos em polifenóis, considerados com alto poder antioxidante, principalmente da classe antocianinas, estão sendo cada vez mais utilizados na prevenção de doenças relacionadas à síndrome metabólica. Um fruto que se destaca por apresentar essa propriedade é o açaí ( Euterpe oleracea). O Brasil é o maior produtor da fruta e o mercado estrangeiro vem investindo na sua importação para utilização tanto na indústria alimentícia quanto farmacêutica. O objetivo do estudo foi realizar uma extensa revisão da literatura sobre as propriedades funcionais do açaí relacionadas à síndrome metabólica. A busca de dados foi realizada em bases, como Pubmed, Web of Science, Scielo e Science Direct. Assim, observou-se que Euterpe oleracea é um fruto rico em antocianinas, as quais atuam modulando o metabolismo lipídico para minimizar os danos no organismo causados pelo estresse oxidativo, desencadeado por doenças crônicas.
Composição nutricional de geleias de umbu-cajá durante estocagem em temperatura ambiente
Authors: Oliveira Emanuel Neto Alves de , Santos Dyego da Costa , Rocha Ana Paula Trindade , Gomes Josivanda Palmeira , Feitosa Regilane Marques , Feitosa Bruno Fonsêca
Published: August 2018

Resumo Objetivou-se, com o estudo, avaliar a composição nutricional de geleias de umbu-cajá elaboradas com sacarose e aspartame, durante estocagem em temperatura ambiente. Foram elaboradas as formulações a partir de uma mistura com quatro partes de água para seis partes de polpa, pectina e açúcar cristal, nas formulações convencionais, e aspartame nas formulações dietéticas. As formulações foram aquecidas e concentradas até atingir aproximadamente 63°Brix (geleias convencionais com açúcar) e 12,5°Brix (geleias dietéticas com aspartame), com posterior acondicionamento em potes de vidro transparentes e mantidos por 180 dias em condições ambientais, com análise da composição nutricional no tempo inicial (após processamento) e a cada 30 dias de armazenamento. Verificou-se que as geleias dietéticas apresentaram boa estabilidade nutricional durante o período de estocagem, não sendo detectadas alterações significativas nos valores de cinzas, teor de água, proteínas, valor calórico, carboidratos e açúcares totais. Quanto às geleias convencionais, constatou-se que os 180 dias de armazenamento promoveram aumentos significativos para carboidratos, nas calorias e nos açúcares redutores, e reduções significativas para teor de água, açúcares totais e açúcares não redutores, enquanto que os valores de cinzas se mantiveram estatisticamente estáveis, assim como os de proteínas.
Helminth infections and hybridization between Haemonchus contortus and Haemonchus placei in sheep from Santana do Livramento, Brazil
Authors: Almeida Fabiana Alves de , Bassetto César Cristiano , Amarante Mônica Regina Vendrame , Albuquerque Ana Cláudia Alexandre de , Starling Renan Zappavigna Costa , Amarante Alessandro Francisco Talamini do
Published: August 2018

Abstract The occurrence and intensity of helminth infections were evaluated in sheep from pastures shared with cattle. In 2015 and 2016, young male sheep acquired in Santana do Livramento, Rio Grande do Sul, Brazil, were finished in integrated crop-livestock system. We selected the 12 sheep that showed the highest number of nematode eggs per gram of faeces to search for worms in the gastrointestinal tract. Haemonchus contortus and Trichostrongylus colubriformis were the major parasites. H. contortus presented mean intensities of 1,159 and 257 worms in 2015 and 2016, respectively. T. colubriformis displayed mean intensities of 4,149 and 2,427 worms in 2015 and 2016, respectively. Of the 127 male specimens of Haemonchus spp. analysed by Polymerase Chain Reaction (PCR), 125 were H. contortus, one Haemonchus placei and one hybrid. Other species detected were Cooperia punctata , Cooperia pectinata, Cooperia spatulata, Cooperia curticei, Ostertagia ostertagi, Teladorsagia circumcincta , Trichostrongylus axei, Nematodirus spathiger , and Trichuris ovis. Twenty lambs presented cysts of Taenia hydatigena in the liver and mesentery. One lamb presented Coenurus cerebralis, the larval stage of Taenia multiceps, in the brain. In conclusion, sheep from pasture shared with cattle presented a high diversity of nematode species. H. contortus and H. placei co-infection occur with consequent hybridization.
Relación entre conocimientos, actitudes y prácticas de higiene en manipuladores de alimentos en quioscos de Instituciones Educativas Públicas de Ate, 2017
Authors: García Loyaga Geordy Holmes , Salavarria Barzola Luiggi Wilman
Published: August 2018

Objetivo: Determinar la relación entre conocimientos, actitudes y prácticas de higiene en manipuladores de alimentos en quioscos de instituciones educativas públicas de Ate. Metodología: Enfoque cuantitativo, de corte transversal, diseño no experimental, y tipo correlacional. Los participantes estuvieron conformados por 145 manipuladores de alimentos de 70 quioscos escolares. El instrumento que se utilizó fue un cuestionario de preguntas sobre conocimientos y actitudes de higiene del manipulador de alimentos y una ficha de verificación de prácticas. Resultados: Los resultados indicaron que el 78.6% de los participantes presentan un conocimiento alto, el 87.6% presenta niveles de actitudes favorables, mientras que el 73% de los manipuladores presentan adecuadas prácticas sobre higiene de alimentos. Con respecto a la correlación, mediante la prueba estadística de Rho de Spearman, se demostró que existe correlación estadísticamente significativa entre el conocimiento y las actitudes de higiene de los manipuladores de alimentos (p<.05). También se evidenció que existe correlación estadísticamente significativa entre el conocimiento y las prácticas de higiene de manipuladores de alimentos (p<.05). Mientras que, entre las actitudes y las prácticas de higiene de manipuladores de alimentos, se observa que no existe correlación estadísticamente significativa (p>.05). Conclusión: los manipuladores de alimentos poseen conocimientos, actitudes y prácticas adecuadas en la mayoría de los temas abordados.
Liposome binding assay v1
Authors: Testerink Christa , Froyd-Rankenberg Anne
Published: August 2018

Standard protocol to examine lipid binding of the proteins isolated from the E.coli with the GST tag
Histological Observation of Tissues v1
Authors: Zhao Honghao , Chong Jasmine , Tang Rong , Li Li , Xia Jianguo , Li Dapeng
Published: August 2018

The different kinds of stained histological sections are widely used to detect and observe physiological and pathological changes in various tissues.
COMPARATIVE IMMUNOHISTOCHEMICAL EVALUATION OF E-CADHERIN AND Β-KATENIN EXPRESSION IN METASTATIC AND NON-METASTATIC BREAST CANCER OF NON-SPECIFIC TYPE
Authors: Mnikhovich M. V. , Kakturskiy L. V. , Bezuglova T. V. , Midiber K. Yu. , Bun’kov K. V. , Erzieva A. G.
Published: August 2018

Objective:an immunohistochemical analysis of the features of expression, distribution and interaction of E-сadherin and β-сatenin proteins in primary mammary tumors.

Materials and methods.The study group consisted of 148 relevant patients with breast cancer (BC), including patients with metastases in lymph nodes (n = 12) and liver (n = 45). E-сadherin and β-сatenin expression on BC cells was determined using immunohistochemical method with specific antibodies.

Results.It was shown that the reduction and the total absence of E-сadherin expression was observed much more often in patients with BC with metastases in liver, than in patients without metastases (70 % of cases versus 30 % of cases respectively). An increase of cytoplasmic immune reactivity and a nuclear translocation of β-сatenin are found in more than 80 % cases of BC with metastases.

Conclusion.The changes in the expression of E-сadherin and β-сatenin in tumor cell can be considered as factors of a non-favorable prognosis of BC. The emergence of β-сatenin expression indicates the activation of a signaling pathway which is triggered by the aberrant expression of epithelial cadherins leading to an increased mobility and invasion of tumor cells.
Virtual Reality in Early and Preschool Childhood
Authors: Smirnova E.O. , Matushkina N.Y. , Smirnova S.Y.
Published: August 2018

Russian and foreign studies suggest that there is a significant increase in the use of computer programmes by preschool children, and that children are generally introduced to computers at a much younger age, practically in their first months of life. Even though the majority of sociological studies show that computer technologies are in high demand by small children and their parents, psychological exploration into this phenomenon is both insufficient and contradictory. Some researchers argue that computer games have a destructive effect upon the child’s development, while others present data proving their positive impacts. We suggest that sociological quantitative methods may not be appropriate in this case and that comparative analysis of the child’s activity with virtual and real material would provide a better understanding. The main part of our paper focuses on this very analysis. We describe outcomes of a study showing that children’s interactions with electronic gadgets differ substantially from the more traditional forms of child activity and cannot compensate for the lack of the latter. In the final part of the paper we provide some recommendations on how to choose computer programmes for children of late preschool age.
A Recurrence of a Giant Odontogenic Keratocyst: Radiographic Follow-Up
Authors: Mendez Luis Alberto , Martinez Ricardo , Echavarria David Josue , Gonzalez Raul Antonio
Published: August 2018

Odontogenic keratocyst could be a very aggressive lesion which may be imperceptible for the patient, not giving any type of symptomatology. This is usually discovered as a finding during a clinical evaluation of the maxillofacial area. The diagnosis of this lesion is merely histological, although it has some radiographic features that presumptively indicate the diagnosis. During a dental school brigade a patient came referring dental mobility, periodontal disease was absent and oral examination revealed a large swelling identified in the body of the mandible. Imaging studies revealed a large central lesion diagnosed as OKC when biopsy was performed. After enucleation and curettage of the lesion radiographic follow-up was conducted every six months, at the third six month period recurrence of the lesion was present and surgical excision was performed with the recommendation of and strict radiographic follow-up in quarterly periods.
Analisis kontribusi pembiayaan mudharabah dan murabahah terhadap pendapatan operasional bank syariah
Authors: Nurjannah Novia Rosi
Published: August 2018

The purpose of this study was to determine the apalication of mudharaba and murabaha financing on BMI and the contributions made financing on operating revenues of bank as well as assessing the financial performance of bank through the financial statements and evaluating the suitability of the application that was done BMI with PSAK 105 and 102. This study used descriptive qualitative approach, namely by looking at the financial reports of 2014 and conducted interviews. This research was to know the implementation of murabaha and mudharaba financing to operating income as well as assessing the financial performance and evaluating the suitability of the application done BMI with PSAK 105 and 102. The results of this research shows that the implementation of murabaha and mudharaba financing provided funds to customers for investments and sold goods. Mean while the bank’s contribution to the operating income of the profit/ margin derived of financing. BMI operating income obtained from various bank products and services. Financial performance that was measured by financial ratios indicated that the value of ROA was well under the Bank Indonesia regulation and BOPO ratio values can be concluded that the effeciency of operational costs incurred by the bank in good condition and not in a state of trobled banks. The accounting treatment of murabaha and mudharaba financing which included presentation, measurement, disclosure adn recognition carried BMI in Accordance with the application of PSAK 102 and 102.
Analisis Penetapan Harga Jual Pembiayaan Murabahah pada Lembaga Keuangan Syariah Bank dan Non Bank
Authors: Sikrillah Lailatul Sikrillah
Published: August 2018

This study aims to determine the selling price of murabaha financing application and calculation of profit margins on BRISyariah, BPRS Bumi Rinjani and UJKS El-Dinar. The research method used is a qualitative research method with a decriptive approach. Where data is the primary data obtained in the form of interviews with the parties concerned and secondary data in the form of data processing can be acconted for from a reliable source to conduct library research, interviews and internet. The result of this study found that setting the selling price on BRISyariah Murabahah Financing, BPRS Bumi Rinjani and UJKS El-Dinar that use the same basic price plus a profit margin. As for determining the profit margin that the bank sets its own and equally consider five factors determining the margin is the profit margin on everage Islamic Bank (Direct Competitor’s Market Rate/ DCMR), the interest rate the everage conventional banks (indirect Competitor’s Market Rate/ ICMR), the result of third-party funds (Competitive Expected Return for Investor/ ECRI), Overhead Cost, profit targets taking into account inflation and interest rate markets. In a benefit margin calculations using a flat (fixed).
The Infrared Fixed Points of 3d $\mathcal{N}=4$ $USp(2N)$ SQCD Theories
Authors: Assel Benjamin , Cremonesi Stefano
Published: August 2018

We derive the algebraic description of the Coulomb branch of 3d \mathcal{N}=4𝒩=4USp(2N)USp(2N) SQCD theories with N_fNf fundamental hypermultiplets and determine their low energy physics in any vacuum from the local geometry of the moduli space, identifying the interacting SCFTs which arise at singularities and possible extra free sectors. The SCFT with the largest moduli space arises at the most singular locus on the Coulomb branch. For N_f > 2NNf>2N (good theories) it sits at the origin of the conical variety as expected. For N_f =2NNf=2N we find two separate most singular points, from which the two isomorphic
components of the Higgs branch of the UV theory emanate. The SCFTs sitting at any of these two vacua have only odd dimensional Coulomb branch generators, which transform under an accidental SU(2)SU(2) global symmetry. We provide a direct derivation of their moduli spaces of vacua, and propose a Lagrangian mirror theory for these fixed points.
For 2 \leq N_f < 2N2≤Nf<2N
the most singular locus has one or two extended components, for N_fNf odd or even, and the low energy theory involves an interacting SCFT of one of the above types, plus free twisted hypermultiplets. For N_f=0,1Nf=0,1 the Coulomb branch is smooth. We complete our analysis by studying the low energy theory at the symmetric vacuum of theories with N < N_f \le 2NN<Nf≤2N, which exhibits a local Seiberg-like duality.
Marketing strategy of public joint stock company «United aircraft corporation»
Authors: Ermakov Dmitrii Nikolaevich , Raizman Valeriia Vladimirovna
Published: August 2018

The article analyzes the development of modern marketing strategy of «Public Joint Stock Company United Aircraft Corporation». The main activities of the organization are considered.
Boxing as type of martial art
Authors: Voronov Nikolay Andreevich
Published: August 2018

Origin of boxing and its formation from amateur boxing to professional is considered in article. As rules of conducting fight from Ancient Rome and as the boxing became the Olympic sport changed up to now is studied. The box demands from the fighter physical force and endurance, excellent reaction and coordination, the perfected equipment. Skills of the boxer are poured extremely effective in extreme situations when it is necessary to stand for itself, for the relatives, for justice.
The concept of marriage, the conditions and procedure for its conclusion
Authors: Tolenova Anzhela Olegovna
Published: August 2018

The author in this article analyzes the notion of marriage and also lists the conditions and procedure for concluding a marriage union between people. This term is considered in the work both in narrow and broad senses, as well as in legal and social aspects.
RayMan and SkyHelios as tools of urban climatology simulation
Authors: Al Savafi Mokhammed Khasan
Published: August 2018

Climatological information and data on climate and factors that influence climate are of great importance for obtaining complex indicators of climate assessment in urban areas. Models RayMan and SkyHelios are two free available micro-scale models. They are used to calculate and evaluate skyview factors (SVF), the duration of sunshine, shadows and radiation fluxes. In addition, the RayMan model is able to evaluate the modern thermal indicators used in human biometeorology. Two models coincide and link several data formats, for example GIS results and information transfer for subsequent processing in urban climatological studies and problems. The final result of the model is the calculation of the average temperature of eradiation, which is required in the model of the human energy balance and, thus, for the assessment of the thermal bioclimate.
Comparative effectiveness of avelumab versus chemotherapy in Merkel cell carcinoma: innovative use of patient insights
Authors: Bharmal Murtuza , Marrel Alexia , Hennessy Meliessa , Fofana Fatoumata , Lambert Jérémy , Arnould Benoit
Published: August 2018

Aim:
To assess patient experience with chemotherapy and avelumab in metastatic Merkel cell carcinoma (mMCC).
Methods:
In the JAVELIN Merkel 200 trial, chemotherapy-refractory mMCC patients could participate in optional qualitative interviews at baseline documenting recollection of previous chemotherapy experience, and at weeks 13/25 documenting current experience with avelumab. Functional Assessment of Cancer Therapy subscale for melanoma questionnaire (FACT-M) was administered in parallel.
Results:
In our sample, chemotherapy was associated with an unpleasant experience. On selected FACT-M items addressing chemotherapy-impacted concepts, most patients receiving avelumab were improved or stable; few worsened. In addition, a few patients spontaneously reported experiencing less toxicity with avelumab than experienced during previous chemotherapy.
Conclusion:
This approach merging qualitative and quantitative data suggests that mMCC patients report a better experience with avelumab than with chemotherapy.