bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of circulatory chemerin levels with the severity of pre-eclampsia: A systematic review and bootstrapped meta-analysis
Authors: Varikasuvu Seshadri Reddy , Madhuri Mridul , Ali Asgar , Gowtham K , Jegatheesan Janani , Ranjan Ashish , Kumar Abhinash , Kumari Bandana , Tiwari Meenakshi , Sharma Sadhana
Published: December 2024

Introduction

This study presents a systematic review and meta-analysis to investigate the association between circulating chemerin levels and the severity of preeclampsia (PE).

Material and Methods

A thorough search was conducted across multiple databases, including PubMed/MEDLINE, SCOPUS, and the Cochrane Library, up to March 31, 2024, focusing on observational studies that compared chemerin levels in patients with severe versus mild PE. Two independent reviewers extracted mean and standard deviation (SD) values of chemerin levels from these studies. The quality and risk of bias of the included studies were assessed using the Newcastle–Ottawa Scale. Standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated to evaluate the difference in chemerin levels between severe and mild PE groups. Sensitivity analyses were performed to address heterogeneity and ensure the reliability of the findings. Additionally, a bootstrapped meta-analysis with 1,000 and 10,000 simulations was conducted to further validate the results.

Results

Six observational studies were included in the analysis. The findings revealed that patients with severe PE had significantly higher chemerin levels compared to those with mild PE (SMD 1.55, 95% CI 0.67–2.43, p < 0.0001). The bootstrapped meta-analysis supported the accuracy of these findings (SMD = 1.54, CI = 0.74–2.38). No publication bias was identified using Begg’s and Egger’s tests, and the sensitivity analysis confirmed the robustness of the results.

Conclusion

This meta-analysis provides compelling evidence that chemerin levels are significantly elevated in patients with severe PE compared to those with mild PE. Further research is warranted to investigate the potential of circulating chemerin as a diagnostic marker for PE severity.
Diagnostic utility of antibodies to structural protein and fibroblast intermediate filament, vimentin, in the detection of rheumatoid arthritis
Authors: Sabitha Dunna , Sai Baba K. S. S. , Dominic Sachin , Rajasekhar Liza , Bhaskar Madrol Vijaya , Mohammed Noorjahan , Khan Siraj Ahmed , Sreedevi N. N. , Mohan Iyyapu Krishna
Published: December 2024

Objectives:

This study aimed to evaluate the specificity and sensitivity of serum anti-mutated citrullinated vimentin (MCV) antibodies in rheumatoid arthritis (RA) patients and to determine their diagnostic utility compared to anti-cyclic citrullinated peptide antibodies and rheumatoid factor (RF).

Materials and Methods:

This study employs a cross-sectional design. Patients were categorized using the 2010 American College of Rheumatology RA criteria. The first group consists of 60 cases, of which 30 are seropositive RA, and 30 are seronegative RA. The second group consists of 60 controls, of which 30 are RF-positive connective tissue disorder (CTD) cases and 30 are healthy. Enzyme-linked immunosorbent assay kits were used to quantify the amounts of anti-MCV and anti-cyclic citrullinated protein.

Statistical analysis:

Version 9 of GraphPad Prism was utilized for doing the statistical analysis. We employed the Kolmogorov-Smirnov test, one-way ANOVA, Student’s t-test, the Kruskal-Walli or Mann-Whitney U tests, and Fisher’s exact or Chi-Square tests for statistical analysis. To study associations between variables, Spearman’s correlation test is used.

Results:

The anti-MCV (ng/mL) median concentrations in healthy controls, CTD controls, seronegative RA, and seropositive RA are 1.487, 5.294, 10.51, and 7.985, respectively, and show a significant increase (P < 0.05) in comparison to healthy controls. Seropositive and seronegative RA subjects did not differ statistically significantly in their anti-MCV levels. According to receiver operating characteristic analysis results, anti-MCV has 100% sensitivity and 83.33% specificity in seropositive RA cases with an optimal cutoff of 6.38 ng/mL and 100% sensitivity and 83.33% specificity in RF-negative RA cases with an ideal cutoff of 6.63 ng/mL.

Conclusions:

The higher levels found in both seropositive and seronegative cases of RA suggest the possibility of using serum anti-MCV as a sensitive RA marker. Anti-MCV may help in the diagnosis of RA, especially seronegative arthritis.
АНАЛИЗ РЫНКА АУДИТОРСКИХ УСЛУГ В РОССИИ
Authors: Ермишина О.Ф. , Кузнецова А.С. , Хусаинова Э.Э. , Круглова В.С. , Чебакова Н.А.
Published: December 2024

Результативность деятельности аудиторских компаний спо- собствует принятию эффективных управленческих решений и успешной ра- боте участников рынка аудиторских услуг в РФ. В исследовании на основе статистических данных представлена оценка состояния российского рынка аудиторских услуг, выявлены ключевые проблемы и возможности, определе- ны пути и стратегии дальнейшего развития. Также, дана оценка достигнутого уровня развития рынка аудиторских ус- луг в РФ, проведена сравнительная характеристика их экономических пока- зателей. Определено конкурентное преимущество и выявлены проблемы, с которыми сталкиваются аудиторские компании в связи с поправками Феде- рального закона об аудиторской деятельности, выявлены их последствия. Исследование позволило авторам оценить географию аудиторской дея- тельности по регионам РФ, рассмотреть динамику результативности работы ведущих аудиторских компаний в России и разработать рекомендации с це- лью повышения их деловой репутации.
РЕАЛИЗАЦИЯ ПЛАТФОРМЫ ДЛЯ ВЗАИМНОГО ШЕРИНГА ИГРОВЫМИ И РАБОЧИМИ АККАУНТАМИ В РАМКАХ ПОДДЕРЖКИ РОССИЙСКИХ ПОЛЬЗОВАТЕЛЕЙ В УСЛОВИЯХ САНКЦИЙ
Authors: Стерхов А.А. , Чуланов Е.В.
Published: December 2024

Статья посвящена актуальной на современном этапе разви- тия российской экономики проблеме эффективного преодоления западных санкций с помощью шеринга в сфере высоких технологий. Авторами статьи поставлена цель создания на бесплатной основе приложения, бота, сообще- ства в котором граждане Российской Федерации и дружественных государств смогли бы предоставлять друг другу доступ к аккаунтам c определенной про- граммой, подпиской. В рамках реализации поставленной цели проведена исследовательская работа по изучению специфики шеринга как экономиче- ского явления, выбраны оптимальные методы, с помощью которых можно до- биться поставленной цели; проанализирован комплекс проблем с доступом к информационному обеспечению у граждан Российской Федерации, который предполагается решить с помощью внедрения и реализации авторского про- екта. В статье рассматриваются возможности и принципы создания специ- альной программы для предоставления пользователям возможности делит- ся своими аккаунтами. Подробно раскрывается поэтапный план авторского проекта по реализации платформы для взаимного шеринга игровыми и ра- бочими аккаунтами, доступной не только для граждан Российской Федера- ции, но и всех дружественных стран, в том числе, входящих в экономическое объединение БРИКС. В результате проведенного исследования произведена формализация процессов в проекте, намечены основные направления раз- вития, готовый научный продукт был представлен в виде проекта и завоевал признание специалистов и общественности.
ПРОФИЛАКТИКА И РАЗРЕШЕНИЕ КОНФЛИКТОВ В ОРГАНИЗАЦИИ
Authors: Есикова Р.С. , Иванова Е.Ю.
Published: December 2024

В статье выявлены определение конфликта, факторы, влияю- щие на его развитие в организации. Конфликт является результатом противо- речий интересов, ценностей, мотивов индивидов, проявляющихся в процессе и взаимодействия при осуществлении трудовой деятельности, решения ор- ганизационных вопросов. Конфликт имеет двойственный характер, обуслов- ленный его конструктивным и негативным воздействием на организацию и социально-психологический климат в коллективе. Выделены основные ста- дии развития конфликта: предконфликтная стадия, открытый конфликт, за- вершение конфликта и постконфликтная стадия. Управление конфликтами представляет собой вид управленческой деятельности, состоящей в воздей- ствии на участников конфликта с целью поиска причин возникновения кон- фликта и их устранения. Содержание управления конфликтами зависит от этапа развития конфликта. Основными способами управления конфликтами выступают предупреждение, прогнозирование, стимулирование, регулиро- вание и разрешение. Выделяют две группы методов управления конфлик- тами: структурные и межличностные. В рамках данных методов могут быть реализованы различные способы управления конфликтами.
ИНДИКАТИВНЫЙ АНАЛИЗ И ОЦЕНКА ЗДРАВООХРАНЕНИЯ В ТЕРРИТОРИАЛЬНО-ОТРАСЛЕВОЙ ЭКОНОМИКЕ
Authors: Кантемирова М.А. , Набиева А.Р. , Зангиева Д.Т.
Published: December 2024

В статье исследуются методологические подходы к индика- тивному анализу и оценке системы здравоохранения в территориально-от- раслевой экономике. Основное внимание уделяется разработке системы показателей, которые позволяют объективно оценивать эффективность функционирования здравоохранения на различных уровнях — региональном и отраслевом. В работе анализируются ключевые аспекты, влияющие на до- ступность и качество медицинских услуг, включая финансирование, кадро- вое обеспечение, инфраструктуру, инновации и региональные особенности. Представлены результаты эмпирических исследований, проводимых на при- мере различных регионов, что позволяет выявить существующие проблемы и потенциал для улучшения. Авторы предлагают рекомендации по совер- шенствованию управления здравоохранением, основанные на индикатив- ном подходе, которые могут быть использованы для разработки стратегий и планов развития системы здравоохранения.
ОСОБЕННОСТИ И ПРОБЛЕМЫ ПЕРЕХОДА ОТ ИНДУСТРИИ 4.0 К ИНДУСТРИИ 5.0 В РОССИИ
Authors: Горшков С.В. , Малыхина И.О.
Published: December 2024

В представленной статье рассматриваются принципы и от- личительные черты концепций Индустрия 4.0 и Индустрия 5.0, а также осо- бенности и проблемы перехода для российских компаний. Исследование концепции Индустрия 4.0 основана на научных трудах Клауса Шваба, бла- годаря, его книге, детально были изучены основные положения концепции, положительные особенности, выделены новые возможности для экономики и общества, а также даны рекомендации по подготовке к инновационным из- менениям. Определены российские компании, которые на текущий момент относятся к Индустрии 4.0, но при этом стремятся совершить скачок и пере- йти к Индустрии 5.0. Были выявлены истоки и основоположники происхожде- ния концепции Индустрия 5.0, определены принципы, отличительные черты и главные направления развития предприятий, выходящих на новый уровень. Перечислены главные признаки компаний действующих в рамках Индустрии 5.0. Изучены стратегические планы реализации национальных программ в области цифровизации.
The Role of Health Locus of Control in Walking Time, Hand Grip Strength and Alternate Stepping in a 60-93 Year-Old General Population
Authors:   The Department of Clinical Sciences in Malmö, Division of Geriatric Medicine, Skåne University Hospital, Lund University, Malmö, Sweden, H Ekström , S Elmståhl ,   Division of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund University, Sweden, SL Wranker ,   Division of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund University, Sweden
Published: December 2024

Individuals with an internal locus of control have been shown to be more self-confident and to perform better in several areas, compared to those with an external locus of control. Few studies have investigated the relationship between Health Locus of Control (HLoC) and physical tests. The aim of this study was to investigate whether and to what extent internal, chance and external HLoC is associated with the outcome of walking speed, hand grip strength and alternate stepping physical tests.

In this cross-sectional study, a total of 3,819 individuals, aged 60-93 years, constituted the study population. Associations between internal, chance and external HLoC and the results from the physical tests were examined in linear regression models, adjusted for sex, age, education, moving-related pain in upper extremities, back and lower extremities, heart disease, lung disease, depressive mood and cognition.

The regression models indicated that a higher result on the internal scale was associated with faster walking, a stronger hand grip and a greater number of steps, while a higher result on the external scale was associated with slower walking, lower hand grip strength and fewer steps.

The findings suggest that in a clinical setting, assessment of HLoC may contribute to the understanding of physical performance in terms of walking speed, grip strength and alternate stepping among adults 60-93 years old. Modification to ensure a stronger internal control has the potential to improve the performance of these physical tests, which could be worth considering in a medical or physiotherapeutic assessment.
Factors Associated with Childhood Unintentional Injury: Evidence from Hospital Data of Rajshahi City in Bangladesh
Authors:   Associate Professor, Department of Population Science and Human Resource Development, University of Rajshahi, Bangladesh, Hossain MD Kamal , Mondal MD Nazrul Islam ,   Professor, Department of Population Science and Human Resource Development, University of Rajshahi, Bangladesh, Haque MD Nuruzzaman ,   Professor, Department of Population Science and Human Resource Development, University of Rajshahi, Bangladesh, Rahman MD Aminur ,   Associate Professor, Department of Population Science and Human Resource Development, University of Rajshahi, Bangladesh
Published: December 2024

Background: Childhood injury is becoming a global burden and major public health concern, particularly in developing countries such as Bangladesh. As a result, this study attempted to identify the factors influencing unintentional childhood injuries in Bangladesh.

Methods: A total of 822 data for this study were collected from four (4) particular hospitals in Rajshahi City, Bangladesh, from 2018 to 2019 by direct interviews with respondents using a structured questionnaire. Descriptive and multivariate statistical techniques were used to evaluate the indicated goals.

Results: The most prevalent causes of unintentional injuries were Road Traffic Injuries (RTIs) at 35.5% and falls at 37.7%, with a higher incidence in rural areas, among male children, and those without working status. Significant associations with unintentional injuries were found for variables such as place of residence, child sex, age, parents’ education, household wealth index, number of family members, and children’s working status. Specifically, for both RTIs and fall-related injuries, key predictors included the child’s age, household wealth index, and mother’s marital status.

Conclusions: The findings revealed that specific demographic and socio-economic factors are significantly associated with the risk of childhood unintentional injuries. Children from middle to richest family brackets and larger households face higher risk factors for Road Traffic Injuries (RTIs). Conversely, a higher household wealth index and older age of children are associated with a lower likelihood of experiencing fall-related injuries. Interventions targeting the age of children and household assets could be effective in mitigating unintentional injuries of children.
Accelerating CO₂ Direct Air Capture Screening for Metal-Organic Frameworks with a Transferable Machine Learning Force Field
Authors: Lim Yunsung , Park Hyunsoo , Walsh Aron , Kim Jihan
Published: December 2024

Direct air capture (DAC) of CO₂ is necessary for climate change mitigation, but it faces challenges from low atmospheric CO₂ concentrations and competition from water vapor. Metal-organic frameworks (MOFs) are attractive candidates for DAC owing to their exceptionally high surface area, tunable porosity, and potential for adsorption-based capture processes with relatively low regeneration cost. Identifying optimal MOFs is hindered by their structural complexity, the vastness of their chemical space, and the expense of accurate simulations. Here, we present a machine learning force field (MACE-DAC) tailored for CO2 and H2O interactions in MOFs by finetuning the foundation model MACE-MP-0. To address smoothing issues and catastrophic forgetting, we curated the diverse GoldDAC dataset and introduced a continual learning loss function. To efficiently sample gas configurations, we developed the DAC-SIM package that uses MLFFs to achieve ab initio quality thermodynamics based on Widom insertion at computational speeds comparable to classical force fields. High-throughput screening on more than 8,000 synthesized MOF structures was performed to identify optimal MOFs and extract important chemical features. This approach overcomes prior limitations in describing CO2/MOF and H₂O/MOF interactions, providing a scalable and accurate framework for accelerating DAC research for porous materials.
Development of an Automated Workflow for Screening the Assembly and Host-Guest Behaviour of Metal-Organic Cages towards Accelerated Discovery
Authors: Basford Annabel , Bernardino Aaron Hero , Teeuwen Paula , Egleston Benjamin , Humphreys Joshua , Jelfs Kim , Nitschke Jonathan , Riddell Imogen , Greenaway Rebecca
Published: December 2024

Metal-organic cages (MOCs) are a class of self-assembled materials with promising applications in chemical purifications, sensing, and catalysis. Their potential is, however, hampered by challenges in the targeted design of MOCs with desirable properties. MOC discovery is thus often reliant on trial-and-error approaches and brute-force manual screening, which are time-consuming, costly and material-intensive. Translating the synthesis and property screening of MOCs to an automated workflow is therefore attractive, to both accelerate discovery and provide the datasets crucial for data-led approaches to accelerate MOC discovery and to realize their targeted properties for specific applications. Here, an automated workflow for the streamlined assembly and property screening of MOCs was developed, incorporating automated high-throughput screening of variables pertinent to MOC synthesis, data curation and automated analysis, and development of a host:guest assay to rapidly assess binding behavior. Computational modelling supplemented this automated experimental workflow for post priori rationalization of experimental outcomes. This study lays the groundwork for future large-scale MOC screening: from a relatively modest screen of 24 precursor combinations under one set of reaction conditions, 3 clean MOC species were identified, and subsequent screening of their host:guest behavior highlighted trends in binding and the identification of potential applications in molecular separations.
Breaking Supercapacitor Symmetry Enhances Electrochemical Carbon Dioxide Capture
Authors: Xu Zhen , Liu Xinyu , Mapstone Grace , Coady Zeke , Seymour Charles , Wiesner Selina , Menkin Svetlana , Forse Alexander
Published: December 2024

Electrochemical CO2 capture using supercapacitors offers an energy-efficient approach for mitigating CO2 emissions, but its performance is thought to be hindered by competing CO2 capture and release processes at two identical porous carbon electrodes. To address this, we introduce an asymmetric supercapacitor-battery hybrid system with porous carbon and non-porous metallic zinc as the working and counter electrodes, respectively. The CO2 capture capacity continuously increases as the charging rate decreases with a maximum capacity of 208 mmolCO2 kg–1, surpassing that of an analogous symmetric supercapacitor. Our findings suggest that breaking device symmetry enhances CO2 uptake in capacitive systems by suppressing competing processes, while the non-capacitive zinc counter electrode simplifies the mechanistic picture of capacitive CO2 capture. Extending this approach, we develop asymmetric supercapacitors with two different porous carbon electrodes, demonstrating a 200% increase in CO2 capture capacities at low charging rates. Summarizing, this study pioneers asymmetric systems for electrochemical CO2 capture and establishes a general strategy to enhance both understanding and performance.
Elogio de la radio en tiempo de gritos y silencios
Authors: Carvallo Fernando
Published: December 2024

En el presente ensayo, se resalta la vigencia que mantiene la radio dentro del ecosistema periodístico y cómo se ha adaptado a los cambios tecnológicos, políticos y sociales del mundo actual. Desde sus experiencias, tanto en medios locales como extranjeros, el autor discute los retos que la radio enfrentará en el futuro y la importancia de comunicar para un público amplio y diverso, tratando siempre de superar las expectativas del oyente.
АНАЛИЗ И ФОРМАЛИЗАЦИЯ ЭКОЛОГИЧЕСКОГО ПОВЕДЕНИЯ НАСЕЛЕНИЯ
Authors: РЮМИНА ЕЛЕНА ВИКТОРОВНА
Published: December 2024

Цель работы состоит в количественной оценке экологического поведения населения и выявлении влияющих на него факторов. Методы проведения исследования. Экологическое поведение рассмотрено в совокупности трех процессов взаимодействия населения с природной средой и ее ресурсами: образование твердых бытовых отходов, водопотребление и потребление электроэнергии в быту. Для каждого процесса определены количественные показатели. В статье представлена авторская разработка индекса экологического поведения населения и методика его построения для российских регионов на основе данных официальной статистики. Выявлены факторы, влияющие на экологическое поведение населения, – природно-климатические, экономические, социальные. Область применения результатов. Результаты выполненной работы могут быть использованы в научных исследованиях для характеристики населения в экологическом и природно-ресурсном аспектах, региональными органами социального управления при работе с населением, природоохранными организациями при разработке стратегий ресурсосбережения. Выводы и результаты. Построены частные индексы водо-, энергопотребления населением в быту и образования твердых бытовых отходов, а также сводный индекс экологического поведения населения. Проанализирована дифференциация регионов по показателям экологического поведения. Выявлены факторы, влияющие на ресурсопотребление и образование отходов. Показана сильная зависимость экологического поведения от материального уровня жизни населения.
СРАВНИТЕЛЬНАЯ ХАРАКТЕРИСТИКА СОЦИАЛЬНО-ЭКОНОМИЧЕСКОГО РАЗВИТИЯ ГОРОДОВ СЕВЕРО-КАВКАЗСКОГО ФЕДЕРАЛЬНОГО ОКРУГА
Authors: ДЕНЕВИЗЮК ДМИТРИЙ АЛЕКСАНДРОВИЧ
Published: December 2024

Предмет исследования. Совокупность социально-экономических процессов, протекающих в современных условиях развития городов. Метод. Методологической основой исследования выступили положения фундаментальных и прикладных работ исследователей в области региональной экономики и управления социально-экономическими системами. Исследование осуществлялось на основе общенаучных подходов с применением методов обобщения, сравнительного анализа и статистической обработки информации. Результаты. Проведен анализ основных параметров функционирования городов с численностью населения более ста тысяч человек, расположенных в Северо-Кавказском федеральном округе, позволивший выявить особенности, неоднозначные тенденции, складывающиеся диспропорции и проблемы, проявляющиеся в отдельных сегментах городского социально-экономического развития. Область применения. Представленное исследование может быть использовано органами местного самоуправления при разработке программных документов в области городского развития.
ГЛОБАЛИЗАЦИЯ И ЕЕ ВЛИЯНИЕ НА ЛОГИСТИКУ И МЕЖДУНАРОДНЫЕ ГРУЗОПЕРЕВОЗКИ
Authors: ЕРМАКОВА ЕЛЕНА ВЛАДИМИРОВНА
Published: December 2024

Цель работы состоит в анализе сферы грузоперевозок, подвергающейся непрерывным изменениям и переменам. В эпоху глобализации подобные изменения стали наиболее интенсивными, они влияют на жизнедеятельность компаний и бизнес-среду. Таким образом, актуальность приобретает вопрос о том, какие тенденции и проблемы возникают в данный период в сфере международной логистики. В целом, эта область приобретает новое измерение и становится еще более важной для успешного функционирования мировой экономики. В данной статье будет более подробно описан сам период глобализации, ее влияние на логистику и международные грузоперевозки, рассмотрены основные направления в развитии международных грузоперевозок в данный период и указаны проблемные области, с которыми сталкиваются логистические компании, работающие на международном рынке.
МЕТОДЫ УПРАВЛЕНИЯ ГОСУДАРСТВЕННОЙ СОБСТВЕННОСТЬЮ И ИХ ЭВОЛЮЦИЯ
Authors: ЦИНПАЕВА ФАРИДА СУЛЕЙМАНОВНА , АБДУЛЛАЕВА ЗАРЕМА МАХМУДОВНА , АЛИШБИЕВА МАККА ОСМАНОВНА
Published: December 2024

Цель работы состоит в том, чтобы раскрыть становление и развитие методов управления государственной собственностью в контексте смены общественно-экономических формаций. Особое внимание будет уделено зарождению правовых отношений и формированию понятия «государственная собственность». Авторы попытаются рассмотреть данную категорию с позиции права и с экономической точки зрения. Для этого в статье будет проведен исторический ракурс форм собственности от её объектов в древности до современных форм. В процессе написания работы авторами будут приведены различные трактовки, концепции советских и российских учёных касательно форм государственной собственности, методов управления ею. Особое внимание авторы уделят эволюции методов управления государственной собственностью в России. В частности, будет рассмотрен процесс приватизации в современной российской экономической системе. Такие формы реорганизации собственности, как доверительное управление, концессионное соглашение, аренда в последние годы весьма популярны. Отсюда большой интерес к ним со стороны экономистов, что нашло отражение в данной статье. Авторы попытались показать сильные и слабые стороны данных форм трансформации отношений собственности.
Estimating the Economic Impact on the Supply of the Agricultural Sector due to Covid-19 in Ecuador
Authors: Garzozi-Pincay René Faruk , Villavicencio-Córdova Xavier , Garzozi-Pincay Yamel Sofia , Acosta-Lozano Néstor Vicente , Castillo-Burbano José Luis , Correa-Soto Sara Rocío , Sánchez-Vera Joselyne Melissa , Herrera-Villamar Joselyn Digmar
Published: December 2024

This research aims to estimate the economic impact that occurred on the supply of the agricultural sector due to COVID-19, which emerged at the end of 2019, becoming the strongest social and economic impact since the Second World War, and which, due to its accelerated level of expansion, in Ecuador a confinement phase was decreed in March 2020, taking the curfew as a priority measure, however, agri-food chains maintained their activities since their products are of great importance. To achieve the objective, a quantitative scope methodology was applied, developing a Linear Regression model with polynomial trends, which related the relevant variables within the agricultural sector to determine the economic impact that occurred on the supply of the agricultural sector caused by confinement. of Covid-19, considering the period between January 2018 until April 2021. These variables are: Gross Agricultural Value Added and the price indices of Inputs, Fertilizers, Agrochemicals, Consumer and Producer. The findings of this analysis show that the COVID-19 lockdown did not directly affect the overall production of the agricultural sector, but rather certain factors. In turn, benefits were generated for the farmer, since the prices of inputs and agrochemical products decreased considerably, reducing production costs. It is concluded that Covid-19 caused changes in five of the six variables evaluated, that is, that confinement affected the most important price factors in the agricultural sector, but not total production.
Teacher Retention in South Africa's Marginalised Schools: Interplay of Psychological Capital, Work Engagement and Job Satisfaction
Authors: Mvana Siyamthanda Wendy
Published: December 2024

The education sector is struggling to retain top-tier teachers, a challenge that can lead to disorder and instability in public schools. Since teachers are key to driving change, it is essential to find effective ways to keep them in the profession, maximise their impact and meet societal needs. This study therefore examines the role of psychological capital in the link between work engagement and job satisfaction, with the aim of tackling retention challenges and improve service delivery. This research, which involved a quantitative cross-sectional survey of 309 teachers in the Tshwane South District of South Africa, finds that psychological capital, which is a teacher’s psychological state that include hope, resilience, optimism, and self-efficacy, significantly mediates the positive connection between work engagement and job satisfaction. Although these results are limited to the sample studied, they highlight the importance of psychological capital in understanding teacher retention. The study suggests that developing strategies to enhance psychological capital could improve both engagement and job satisfaction. Future research should include larger sample sizes to strengthen the external validity of the findings.
Li4Mo5O17 crystals by LTG Cz: faceting and temperature-dependent crystal structure
Authors: Grigorieva V.D. , Fedorenko A.D. , Kuznetsov A.B.
Published: December 2024

An approach to growing Li4Mo5O17 crystals by the low-thermal-gradient Czochralski technique (LTG CZ) was optimized to obtain bulk single crystals with dimensions 70*35*35 mm3. An alteration of temperature parameters during the crystal growth process was proposed. Faceting was studied on a number of Li4Mo5O17crystals grown under varying conditions, Miller indexes of the developed facet families were determined, and based on the obtained data, a reference model of Li4Mo5O17 crystal was visualized. Molybdenum coordination in Li4Mo5O17 crystal was studied by X-ray photoelectron spectroscopy. X-ray diffraction patterns of Li4Mo5O17 were recorded in the temperature range of 323-743 K. Based on obtaining data, thermal expansion vectors were calculated and an expansion ellipsoid was visualized.
Nuvaxovid NVX-CoV2373 vaccine safety profile: real-world data evidence after 100,000 doses, Australia, 2022 to 2023
Authors: Clothier Hazel J , Parker Claire , Mallard John H , Effler Paul , Bloomfield Lauren , Carcione Dale , Buttery Jim P
Published: December 2024

Introduction

Nuvaxovid became available in Australia from February 2022, a year after the first COVID-19 vaccines. This protein-based vaccine was an alternative for people who had had an adverse event to and/or were hesitant to receive an mRNA or adenovirus-based COVID-19 vaccine. Although safety from clinical trials was reassuring, small trial populations, low administration rates and limited post-licensure intelligence meant potential rare adverse events were underinformed.

Aim

We aimed to describe Nuvaxovid’s safety profile in a real-world setting.

Methods

We conducted a retrospective observational analysis of adverse events following immunisation (AEFI) spontaneously reported to SAFEVAC, the integrated vaccine safety surveillance system in Victoria and Western Australia. Reports from 14 February 2022 to 30 June 2023 were analysed by vaccinee demographics, reported reactions and COVID-19 vaccine dose, and compared as reporting rates (RR) per 100,000 doses administered.

Results

We received 356 AEFI reports, following 102,946 Nuvaxovid doses administered. Rates were higher after dose 1 than dose 2 (rate ratio: 1.5, p = 0.0008), primary series than booster (rate ratio: 2.4, p < 0.0001), and in females vs males (rate ratio: 1.4, p = 0.004). Clinically confirmed serious AEFI included 94 cases of chest pain (RR = 91.3), two myocarditis (RR = 1.9) and 20 pericarditis (RR = 19.4). Guillain–Barré syndrome or thrombosis with thrombocytopaenia syndromes were not reported, nor deaths attributable to vaccination.

Conclusion

SAFEVAC’s collaborative data model enabled pooling of clinically reviewed data across jurisdictions, increasing the safety profile evidence for Nuvaxovid and improving the odds for identification and description of rare events. This analysis affirmed the safety profile of Nuvaxovid.
Entrepreneurial Interest Among “Santri” in HEBITREN and Its Impact on SMEs
Authors: Asep Maulana Rohimat  , Astiti Rani Dwi , Arifin Mohammad Rahmawan , Mahmudulhassan
Published: December 2024

This research aims to analyze the factors influencing the entrepreneurial interest of students (santri) in Islamic boarding schools (pesantren) affiliated with HEBITREN (Himpunan Ekonomi Bisnis Pesantren) in Solo Raya. The revealed factors include Self-Efficacy, Risk Tolerance, and The Environmental Atmosphere. The study involved 130 Santri from two HEBITREN-affiliated Islamic boarding schools, namely Muhammad Al-Fatih Islamic Boarding School in Sukoharjo and Al-Izzah Islamic Boarding School in Surakarta. A mixed-method approach, incorporating both quantitative and qualitative methods, was employed. The findings indicate that the most dominant factor influencing the entrepreneurial interest of students is self-efficacy due to these factors being frequently emphasized in every learning process within boarding schools and the significant support from Islamic teachings for the development of entrepreneurial spirit. However, other factors, such as risk tolerance and the environmental atmosphere of the Islamic boarding schools, signilittlect the students' entrepreneurial interest. Some internal factors contributing to the low interest among students include inadequate entrepreneurial training facilities, and the boarding schools' human resources need to improve to foster an entrepreneurial spirit. This research is crucial for formulating appropriate policies for the government to support Islamic boarding schools affiliated with HEBITREN in paying attention to the infrastructure that strengthens the emergence of entrepreneurial spirit and the self-sufficiency of the boarding schools.
Sharia Compliance and Islamic Digital Banking: Empowering SMEs in Indonesia
Authors: Supriyono Supriyono , Terminanto Ade Ananto , Mulazid Ade Sofyan , Suherlan Ade
Published: December 2024

This study explores the role of Sharia compliance in enhancing the adoption and use of Islamic digital banking services in Indonesia, with particular attention to its implications for Small and Medium Enterprises (SMEs). Using a modified UTAUT 3 model, this research incorporates Sharia compliance and trust as critical variables influencing user behavior. A quantitative approach, including an online survey with 129 respondents, was used, and data were analyzed with PLS-SEM. The findings demonstrate that Sharia compliance significantly impacts actual usage but does not moderate the relationship between intention and behavior. Trust and personal innovation also play pivotal roles in driving adoption, while factors such as facilitating conditions, hedonic motivation, and price value were found to have minimal influence. These insights underscore the importance of aligning Islamic digital banking services with Sharia principles to meet the needs of SMEs, ultimately fostering greater trust, efficiency, and technological innovation. The study offers practical recommendations for Islamic banks to better engage SMEs by focusing on Sharia compliance and user trust in their digital services.
The Influence of Digital Transformation Based on Religious Ethics on MSME Performance in the Era of Industry 4.0
Authors: Shofiyuddin Muhammad , Nurhayati Siti , Marlinah Manggor Enny , Zahro
Published: December 2024

This research investigates the influence of digital transformation based on religious ethics on the performance of Micro, Small, and Medium Enterprises (MSMEs) in the era of Industry 4.0. The variables used in this study include digital transformation as the independent variable, MSME performance as the dependent variable, and religious ethics as a moderating variable. This research aims to analyze the extent to which digital transformation affects MSME performance in Pekalongan City, explore the role of religious ethics as a moderating variable that influences the relationship between digital transformation and MSME performance, and identify the challenges faced by MSMEs in Pekalongan in adopting digital transformation without neglecting the religious, ethical values they adhere to. The population in this study consisted of 180 MSMEs, which met the criteria of implementing digital transformation initiatives and having a clear orientation towards religious ethics in their business practices. This research used a census approach, where the entire population was considered the sample. The analysis tool used was Structural Equation Modeling - Partial Least Squares (SEM-PLS) with WarpPLS 8.0 software. The findings indicate that digital transformation has a positive and significant effect on MSME performance, religious ethics has a positive and significant effect on MSME performance, and religious ethics moderates the relationship between digital transformation and MSME performance. The supporting factors for digital transformation among MSMEs include government support, access to technology, and partnerships with technology companies. Meanwhile, the inhibiting factors are low digital literacy, limited financial access, and inadequate digital infrastructure.
Exploring the Importance of Halal Tourism: Cultural Influences on Travel Accommodation Choices Among Middle-Class “Santri” in West Java
Authors: Amin Ali , Semmawi Ramli , Dewi Subkhani Kusuma
Published: December 2024

This article aims to investigate the limited development of Syariah-certified hotels in Indonesia despite the country’s substantial potential in the global halal tourism market. Indonesia has actively promoted halal certification in the accommodation and hospitality industries, supported by central and regional governments. These initiatives align with Islamic hospitality principles, including halal-certified food, the prohibition of alcohol, modest dress codes for employees, and gender-segregated facilities. However, despite the rising discourse on halal tourism, the number of Syariah-certified hotels remains disproportionately low. This study seeks to understand why this gap exists and how the Muslim community perceives Syariah-compliant accommodations. Observations and interviews with 38 middle-class santri groups in West Java, particularly in the Jabodetabek area, reveal that their choice of accommodation is influenced more by cultural factors than religious ideology. Despite being religiously literate, many santri do not prioritize Syariah hotels when traveling. These findings highlight a disconnect between the supply of and demand for Syariah hotels, providing insights into the cultural and practical challenges facing halal tourism development in Indonesia.
DIGITIZATION AS A NECESSARY CONDITION FOR THE DEVELOPMENT OF FOREIGN ECONOMIC ACTIVITY OF THE REGIONS OF RUSSIA
Authors: Shutaeva Elena , Pobirchenko Viktoriya
Published: December 2024

The article is dedicated to one of the key trends of modern society, which has a multiplicative impact on all spheres and socio-economic processes — digitalization. It is emphasized that digitalization of the external economic sphere not only opens up new horizons and opportunities for the development of international economic cooperation, modernization of businesses, and strengthening of the country’s competitiveness on the global stage but also presents numerous challenges and risks.
Using data on the dynamics of digital activity levels among the population and organizations, development of digital infrastructure, and expenditures on digital technologies, an analysis of the impact of digitalization processes on external economic activities at the regional level was conducted. Indicators such as digital literacy of the population and competencies were identified as key factors influencing the effectiveness of digitalization in the regional context. The obtained results allow for the identification of a sustainable trend of growth in all examined indicators. However, nominally low values indicate the need for additional efforts in the area of digital literacy among the population and the development of basic digital skills.
Inequality in the impact of digitalization on external economic activities in the regions (federal districts) of Russia was revealed. Leading regions in terms of digitalization levels, such as the Ural, Central, and Northwestern federal districts, demonstrate high levels of GDP and foreign trade turnover per capita, indicating their high socio-economic development and active participation in external economic activities.
The advantages of digitalization, its role in international transfers and payments by simplifying processes, reducing costs, increasing speed, and enhancing transaction security, are demonstrated. Emphasis is placed on the advantages of digital payment systems in terms of improving accessibility for businesses and consumers, reducing barriers in international transactions.
The conclusions of the study highlight not only the positive aspects of digitalization but also the risks, such as cybersecurity threats, the monopolistic position of major IT companies in the market, and the need for human capital development. The research results can serve as a basis for shaping regional strategies and policies aimed at balancing the positive and negative consequences of digitalization and effectively utilizing digital technologies for sustainable regional development.
PHYTOCHEMICAL COMPOSITION OF ESSENTIAL OIL OF PELARGONIUM GRAVEOLENS L’HÉR. IN CULTURAL CONDITIONS ON THE SOUTHERN COAST OF THE CRIMEA
Authors: Sahno Tat'yana
Published: December 2024

The article presents the results of a study of the mass fraction and component composition of essential oil obtained from the above-ground mass of rose-scent geranium (Pelargonium graveolens L’Hér.), grown in open ground conditions on the Southern Coast of the Crimea (SCC). P. graveolens is a species of the genus Pelargonium, a combined Geraniaceae, naturally produced in the Cape Floristic Region and widely cultivated throughout the world as a valuable ornamental, essential oil and medicinal plant.
The essential oil was obtained by hydrodistillation using Ginsberg apparatus. The component composition of essential oils was determined using a hardware and software complex based on a chromatograph “Chromatek-Crystal 5000.2” equipped with a mass spectrometric detector. Identification was performed based on a comparison of the obtained mass spectra with data from the NIST 14 library (National Institute of Standards and Technology, USA). “MS Search” spectrum search and identification program (USA). Retention indices were obtained by logarithmic interpolation of the presented retention times using the analytical standard of a mixture of reference n-alkanes “Sigma-Aldrich” (Switzerland) and analytical standards “Supelco” (USA). The mass fraction of components in the sample was determined by the percentage normalization method.
The mass fraction of EOs in freshly collected raw materials is 0.22 % and 1.33 % in terms of absolutely dry weight. The essential oil is represented by 41 components, 87.8 % of which have been identified. Based on the results of chromatographic analysis, it was established that the quantitatively predominant components of the EO of the studied sample of P. graveolens under the conditions of the SCC are: terpene alcohols: citronellol – 39.67 %, geraniol – 13.61 % and terpene ether – citronellyl formate 10.58 %. The EO sample was characterized by a small amount of undesirable components, such as isomenthone (5 %) and a complete absence of 10-epi-udesmol and menthone.
By this composition, the EO obtained under the conditions of the SCC is close to samples, produced from raw materials grown in China, Armenia and Tajikistan. The results obtained allow us to consider P. graeolens for the conditions of the SCC as a promising source of natural essential oils of domestic production for the needs of pharmaceutical, perfumery, cosmetics and food industries.
FEATURES OF CEREBRAL HEMODYNAMICS IN PEOPLE OF PRE-RETIREMENT AGE
Authors: Veselovskaya E. , Sevryukova G.
Published: December 2024

The article is devoted to the study of cerebral hemodynamics in people of pre-retirement age, differentiated by age and sex criteria and types of systemic circulation (women (n = 104), men (n = 83).
Objective: to research of the features of cerebral hemodynamics in people of pre-retirement age. Evaluation of blood supply to the brain was carried out at rest using the reoencephalographic method.
The reoencephalographic examination was performed in 4 leads (FM, OM left hemisphere; FM, OM right hemisphere). Indicators were registered: integral index of pulse filling, amplitude-frequency index, rheographic index and time of propagation of the rheographic wave, average vessel filling rate, venous outflow, dicrotic index, diastolic index and coefficient of asymmetry. The type of systemic circulation was determined using the cardiac index.
The predominance of the hypokinetic type in elderly men and women causes significant changes in the ratio of cerebral blood flow to its outflow and indicates a decrease in adaptive reactions of the circulatory system.
Many men and older women have a hypo-kinetic circulating type, which may be an unfavorable feature. People of pre-retirement age with hyperkinetic type of blood circulation can be classified as a risk group, because they have significant deviations of rheoencephalography parameters from the physiological norm.
Changes in the ratio of regional blood inflow to outflow in people over 50 years of age are markers of a decrease in adaptive reactions of the circulatory system. The limit of vasoconstrictor reactions caused by the aging of the body is the cause of deterioration of the conditions of regional blood outflow.
The revealed deviations of rheoencephalography parameters from the physiological norm should be taken into account when conducting functional tests, as well as in programs of prenosological diagnostics, organization of healing and preventive measures.
MANAJEMEN DAN ORGANISASI UNTUK PEMUDA DAN PEREMPUAN ADAT
Authors: Paula Diana Yulia , Yomungga Moses
Published: December 2024

Keindahan hutan Papua membuat siapa pun yang melihatnya terkesima. Selain keindahan keanekaragaman hayati, hutan Papua juga mempunyai peran yang sangat penting dalam mencegah perubahan iklim. Sayangnya, saat ini mereka berada dalam ancaman serius. Organisasi Non-Pemerintah (NGO) dan Organisai / Kelembagaan Adat Pemuda dan Perempuan memiliki peran penting dalam pembangunan sosial, budaya, dan ekonomi masyarakat. bertujuan untuk memperkuat kapasitas lembaga-lembaga tersebut, memperbaiki tata kelola, serta memperkuat kolaborasi antara NGO dan Orgnisasi / Kelembagaan Adat, Pemuda dan Perempuan dalam mendukung kerja-kerja advokasi, pemberdayaan. Pelatihan ini menggunakan metode partisipatif, yang mencakup: presentasi dan ceramah oleh fasilitator ahli., diskusi kelompok., simulasi dan studi kasus., sesi tanya jawab dan latihan praktis dan role play. (24 & 25 Oktober 2024)
Vigilancia tecnológica en el desarrollo de vacunas contra el dengue: una metodología para la revisión del estado técnico y del arte.
Authors: Estrella Santiago Diana Priscila , Oliver Espinoza Rubén
Published: December 2024

Dada la creciente incidencia del dengue y los esfuerzos globales para controlarlo mediante vacunas, el documento ofrece una metodología de vigilancia tecnológica en el desarrollo de vacunas contra la enfermedad. Presenta un enfoque metodológico para revisar el estado técnico y del arte en este campo, utilizando análisis bibliométricos y de patentes. Incluye la identificación de bases de datos, palabras clave específicas, y el análisis de indicadores para evaluar la producción científica y las innovaciones tecnológicas.