bluuebunny/crossref_metadata_2025 huggingface dataset:
DISEÑO CENTRADO EN EL USUARIO: INTERACCIÓN HOMBRE-COMPUTADORA
Authors: Cobarrubias Soto Natividad , Rodríguez López Humberto , Zaldívar Colado Xiomara Penélope
Published: October 2023

En la Interacción Humano-Computadora (HCI: Human-Computer Interaction), el diseño de la interfaz gráfica de usuario cumple un rol imperante en la mediación de las distintas relaciones cognitivas que establece el usuario cuando interactúa con cualquier tipo de dispositivo tecnológico. La comprensión e identificación de los modelos asociados al diseño y desarrollo de estas interfaces posibilita un acercamiento a la lógica del usuario y a cómo facilitar la consecución de sus objetivos.  El presente documento es el abordaje temático relacionado con la asignatura Interacción Hombre-Maquina del programa de estudio (PE) de la Licenciatura en Ingeniería en Sistemas de Información en la Facultad de Informática Mazatlán; y aporta una aproximación teórica desde lo conceptual, metodológico y las normativas que hacen al buen diseño del componente de interacción; las interfaces del usuario y su proceso de desarrollo, sobre las etapas de diseño de interfaces específicas, y de la calidad de uso del producto enmarcadas en el diseño centrado en el usuario.  Se introducen los conceptos básicos de la Interacción Hombre – Computadora, se expone una breve referencia a su evolución. Y se describe el proceso de diseño de la interfaz de usuario, haciendo hincapié en las características más importantes. Se introducen los conceptos de usabilidad, y las normas internacionales para construir interfaces accesibles.
VIRTUALIZACIÓN FORZADA EN LA EDUCACIÓN SUPERIOR: REFLEXIONES POST PANDEMIA
Authors: Rodríguez López Humberto , Cobarrubias Soto Natividad , Zaldivar Colado Xiomara
Published: October 2023

La nueva normalidad [1] post pandemia COVID-19, obliga a una reflexión ante la imposibilidad de medir aun el impacto en la educación superior, que contribuya a identificar realidades y necesidades de la sociedad en su concepción amplia, las tendencias, retos y desafíos de los sistemas educativos; Después de pasar abruptamente de la presencialidad a la virtualidad, de las actuaciones, situaciones y circunstancias; institucionales, de docentes, estudiantes y personal administrativo. De los retos no resueltos de la educación como la falta de calidad, inequidad, inclusión y el financiamiento, cobertura, acceso tecnológico, la apropiación y uso de las Tecnologías de la Información y Comunicación(TIC), conocimiento y aprendizaje digital, analfabetismo digital, brecha digital entre otros. El presente trabajo tiene un carácter documental-teórico y se circunscribe a las experiencias del personal docente generadas en la Facultad de Informática Mazatlán de la Universidad Autónoma de Sinaloa.
INTERNACIONALIZACIÓN DE LA REVISTA ELECTRÓNICA REDTIS MEDIANTE EL INDEXAMIENTO A BASES DE DATOS ELECTRÓNICAS
Authors: Peraza Garzón Juan Fco. , Olivarría González Mónica del Carmen , Salinas Castañeda José Ángel , Tostado Ramírez Manuel Iván , Estrada Lizárraga Rogelio
Published: October 2023

Las revistas digitales son un medio de información sumamente importante desde hace años, ya que además de compartir artículos e investigaciones de interés, pueden ser visitados desde cualquier parte del mundo, y generar datos estadísticos a través de la indexación de revistas y la cita de artículos, esto solo contando con un equipo de cómputo y acceso a Internet.
Esta importancia se debe a que en la última década, la información almacenada en las revistas electrónicas ha ido evolucionando a no solamente tener la información de los artículos guardados solo en el sitio que hospeda la revista, si no que se han creado diversos medios electrónicos que mejoran la búsqueda, ordenamiento y análisis de todos los datos que contienen los artículos, como lo son, los nombres de los autores, el título, el contenido, las citas. Todo esto con el fin de poder analizar toda esa información y generar estadísticas como el número de citas que tienen los artículos, tipo de cita A o B y el factor de impacto. Esto es gracias a la creación de bases de datos electrónicas que almacenan la información de las ediciones emitidas por las diversas revistas electrónicas que cumplen con ciertos requerimientos.
Existen muchas bases de datos electrónicas para almacenar los metadatos de las ediciones de todas las revistas, la mayoría son gratuitas, pero tienen ciertos niveles de rigurosidad que deben cumplir las revistas para poder ser indexadas en ciertas bases de datos.
ANALISIS RANCANGAN E-BUSINESS UNTUK PENGEMBANGAN UMKM DI KEPULAUAN BANGKA BELITUNG (STUDI KASUS PRODUK UNGGULAN SARI JERUK KUNCI, KOPERASI PRODUSEN MELATI MAJU BERSAMA PANGKALPINANG)
Authors: Inawati  , Ruben Manullang Rizal , Zamhari
Published: October 2023

This research was entitled: “Analisis Rancangan E-Business Untuk Pengembangan UMKM Di Kepulauan Bangka Belitung; Studi Kasus Produk Unggulan Sari Jeruk Kunci, Koperasi Produsen Melati Maju Bersama Pangkalpinang”.

The background of this research is based on the necessity for the company to have an online operational platform. The purposes of this study were to plan systematically regarding the Melati Maju Bersama Producer Cooperative in achieving organizational goals that are effective and efficient, to carry out the implementation related to what has been planned so that the Melati Maju Bersama Producer Cooperative achieves the organizational goals set, effective and efficient, and to carry out supervision in the Cooperative Producers of Melati Maju Bersama in order to achieve organizational goals that are effective and efficient.

The method of research is a descriptive qualitative The method used in this study is descriptive with a qualitative approach with the aim of describing and describing existing phenomena, both natural and human engineered, which pays more attention to the characteristics, quality, and interrelationships between activities.

The theories and methods used in this research are the theory of Management, Marketing Management, Consumer Behavior, Marketing Strategy, Management Information System, E-Marketing, Affiliate Marketing, E-Business, E-Commerce, and the Unified Process Rational Methodology (RUP) and PIECE Analysis.

The results of the study prove that: (1) the process of identifying a systematic plan for the Melati Maju Bersama Producer Cooperative in order to improve organizational goals effectively and efficiently is carried out by building / creating a domain or service center that is integrated with the internet., (2) Jasmine Producers Cooperative Maju Bersama in carrying out the implementation process in order to improve organizational goals that are effective and efficient in maximizing the use of hardware, software and brainware., (3) Supervision that occurs in the Melati Maju Bersama Producer Cooperative in order to improve organizational goals that are effective and efficient.
ANALISIS PENGARUH E-COMMERCE DAN SISTEM INFORMASI AKUNTANSI TERHADAP KEPUASAN BELANJA GENERASI MILENIAL DI KOTA PANGKALPINANG (STUDI KASUS PADA PORTAL BELANJA ONLINE SHOPEE.CO.ID)
Authors: Febriyani Desy , Ruben Manullang Rizal , Novika
Published: October 2023

This is the result of a thesis research compiled by Desy Febriyani, Accounting Department STIE-IBEK. The title of this research in Indonesian "Analisis Pengaruh E-Commerce dan Sistem Informasi Akuntansi Terhadap Kepuasan Berbelanja Di Kota Pangkalpinang (Studi Kasus Pada Portal Belanja Online Shopee.co.id)" was run from October 2020 to January 2021.

The purpose of this study was to determine whether the independent variables consisting of: E-Commerce and Accounting Information Systems to the dependent variable, namely Shopping Satisfaction. This research was conducted using qualitative methods of data analysis, descriptive statistics, multiple linear regression, coefficient of determination, assumption test. classics, and hypothesis testing.

The data used in this study are primary data. Statistical data processing uses the form of the JASP 0.9.2.0 program. Partial data processing on the E-Commerce variable has an effect on Millennial Generation Shopping Satisfaction by calculating the t value (3.831)> t table (1.6702) and the sig value 0.000 <0.05 so that H0 is rejected and H1 is accepted. The Accounting Information System variable partially affects the Millennial Generation's Shopping Satisfaction t count (3.664)> t table (1.6702) and the significant value of the Accounting Information System Variable is 0.000 <0.05 so that H0 is rejected and H1 is accepted. Simultaneously, the E-Commerce variable and the Accounting Information System have an effect on Millennial Generation Shopping Satisfaction, it is obtained that the value of Fcount (25.803)> Ftable (3.15) and a significant value of 0.000 <0.05 so that H0 is rejected and H1 is accepted. For R square it is obtained at 0.458 or 45.8%, which means that the independent variable can simultaneously influence the dependent variable by 45.8% and the remaining 54.2% by other variables not used in this study.
PENGARUH AKUNTABILITAS PENGELOLAAN ALOKASI DANA DESA, TRANSPARANSI PENGGUNAN DANA DESA, DAN KEBIJAKAN DANA DESA TERHADAP KESEJAHTERAAN MASYARAKAT (STUDI KASUS PADA DESA BELULUK, KEC. PANGKALAN BARU, KAB. BANGKA TENGAH)
Authors: Yonara Ririn , Tri Setyo Mulyani Hendarti , Hasianda Tigor Ryan
Published: October 2023

This study aims to examine the effect of accountability in managing village fund allocations, transparency in the use of village funds, and village fund policies on community welfare. This study also aims to jointly examine the accountability of village fund allocation management, transparency in the use of village funds and village fund policies on community welfare. This research was conducted in the village of Beluluk, Pangkalan Baru District, Central Bangka Regency.

       This type of research is quantitative research. Types of data used in this study is primary data obtained directly by distributing questionnaires directly to the public Belulu Village. The total population is 3,988 people and the number of samples in In this study, 90 people from the Beluluk Village community as respondents using purposive sampling technique. This study uses the JASP 0.14.1 tool for multiple regression analysis and its analytical methods.

        Based on the results of data analysis, the results show that Village Fund Allocation Management Accountability has a significant positive effect on Community Welfare. The results of the t-test show that the t count is 2,974 > 1,987 t table with a significance value of 0.004 < 0.05, then H1 is accepted. Transparency in the use of Village Funds has a significant positive effect on Community Welfare. The results of the t-test show that t t-count is 3.207 > 1.987 with a significance value of 0.002 < 0.05, then H2 is accepted. The Village Fund Policy has a significant negative effect on Community Welfare. The results of the t-test show that t count is -2.886 > 1.987 with a significance value of 0.005 < 0.05, then H3 is accepted. This study also shows that accountability for managing village fund allocations, transparency in the use of village funds, and village fund policies together have a significant and significant impact on community welfare. The results of the f test show f count 10,901 > 2,711 f table with a significance value of 0.001 < 0.05, then H4 is accepted.
A LIVING CLAIM AS AN ALTERNATIVE TO SOLVING DIVORCE CASE IN THE BOJONEGORO
Authors: Qodir Abdul , Iskandar Hardian , Jaya Wardana Dodi
Published: October 2023

Background. Maintenance is one of the husband's obligations towards his wife, and if the husband does not want to provide for his wife's children when in fact he can according to his ability, then the wife can sue him at the Religious Court. This study aims to examine in-depth script lawsuits as an alternative settlement of divorce cases in Religious Courts, as well as to analyze the efforts of judges and the execution of Religious Court decisions in cases of livelihood claims.
Research Method. The method used is qualitative, while the type of research used was a juridical-empirical approach. A juridical review approach, using legal rules, books, and journals related to the research problem.
Findings. Claims for maintenance can stand alone without having to divorce. The judge as the case breaker always emphasizes that married couples who want to divorce cancel their intention. Therefore, if a divorce case is caused by a husband's negligence in supporting his wife and children, then a wife can file a claim for maintenance to the Court. So, claims for a living can be a solution to the occurrence of a divorce.
Conclusion. A claim for a living can be filed by bringing evidence of a lawsuit in the form of reasons why the wife sues her husband, accompanied by written documents such as a marriage certificate and husband's salary slip, and the amount of maintenance that must be given to his wife's children according to his ability.
LEGAL CASE AND HEALTH PERSPECTIVE OF BULLYING LEADING TO BLINDNESS
Authors: Suyanto Suyanto , Qomariah Siti Nur , Syaiful Yuanita , Fatmawati Lilis
Published: October 2023

Background. Bullying has a negative impact on both the perpetrator and the victim. The biggest impact is experienced by victims of bullying. Victims of bullying experience physical or psychological disorders. The purpose of this study was to explain a legal case and health perspective of bullying leading to blindness.
Research Method. This research was a case report. One case of bullying happened in an elementary school in Gresik. The victim (SAH, 8 years old) was a girl who experienced blindness as a result of bullying by her friends at her school.
Findings. On August 7, 2023, SAH was poked in the right eye by a student because he was reluctant to give money. From that incident, SAH's right eye became blind. The incident took place in the hallway inside the school. The bullying happened 1 year ago and continued until SAH became blind. Seeing the case that occurred at an elementary school in Gresik, there was a connection with Law No. 35 of 2014 concerning child protection. Bullying in this case have an impact on physical disorder and psychological disorder for the victim.
Conclusion. There has been an appeal for bullying in the school environment from the Ministry of Education and Culture. The region has even launched anti-bullying. Prevention efforts and literacy regarding bullying are the school's responsibility.
Determination of fruit quality characteristics of blackberry genotypes growing naturally in Düzce (Türkiye)
Authors: TAŞ Akgül
Published: October 2023

In this study, the morphological, physicochemical and biochemical properties of the fruit of the blackberry (Rubus spp.) genotypes grown naturally in the village of Dağdibi, Kaynaşlı district of Düzce province were determined. Fruit weights of the genotypes ranged from 1.77 g (81KYN10) to 0.80 g (81KYN2). Fruit width ranged from 13.55 mm (81KYN10) to 9.05 mm (81KYN2). Fruit length was determined between 14.26 mm (81KYN10) and 11.09 mm (81KYN2). In terms of the highest rate of amount of soluble solids content (SSC) in the study, 81KYN1 (16.70%), 81KYN3 (15.65%), 81KYN4 (15.40%), and 81KYN5 (16.20%) genotypes were more important. In terms of the highest titratable acidity (TA) value, 81KYN7 (0.52%) and 81KYN13 (0.51%) genotypes were more dominant. The highest L*, a*, b*, chroma and Hue angle values in color value parameters were found as 13.88 (81KYN7), 1.34 (81KYN4), 1.12 (81KYN4), 1.77 (81KYN4) and 40.63 (81KYN1), respectively. In terms of biochemical content, the highest total phenolic amounts were detected in 81KYN2 (45.77 mg GAE/g), 81KYN6 (47.55 mg GAE/g), 81KYN7 (52.16 mg GAE/g) and 81KYN13 (46.31 mg GAE/g) genotypes, the highest total antioxidant capacities were seen in 81KYN1 (29.30%) and 81KYN2 (30.57%) genotypes. Additionally, the highest total protein amounts was determined in 81KYN1 (20.48 g/L), 81KYN3 (20.60 g/L) and 81KYN5 (20.87 g/L) genotypes. As a result of the study, it was concluded that the genotypes that stand out in terms of morphological, physicochemical and biochemical characteristics can be evaluated in functional blackberry production.
MEKANİK PÜSKÜRTME PATERNATÖRÜ TASARIMI, PROTOTİP İMALATI VE PÜLVERİZATÖR MEMELERİNDE AKIŞ TESTLERİ
Authors: ÇÖMLEK Ruçhan , SAYINCI Bahadır
Published: October 2023

Bu araştırmada pülverizatör memelerinin püskürtme paternini belirlemek ve akış düzgünlüğünü kontrol etmek için 60 kanallı 120×100 cm ölçülerinde 20 mm kanal açıklığına sahip tek noktadan püskürtmeli, yüksekliği ayarlanabilir tipte düşük maliyetli bir püskürtme paternatörünün tasarımı ve prototip imalatı yapılmıştır. Paternatörün ölçüm tablasında kullanılan kanallar paslanmaz çelik sacdan imal edilmiştir. Test sisteminin ana gövdesinde yapı çeliğinden üretilmiş profiller kullanılmıştır. Püskürtme sırasında her bir kanalda biriken sıvı, 25 ml hacimli ölçü silindirlerinde toplanmıştır. Her denemeden sonra ölçü silindirlerinde biriken akışkanı tahliye etmek için aç-kapa mekanizması geliştirilmiştir. Her bir ölçü silindirine yerleştirilen işaretleyiciler sayesinde püskürtme paterni izlenebilmiştir. Püskürtme paternini sayısallaştırmak için görüntüleme yapılmış ve değerlendirmeler görüntü işleme tekniğiyle gerçekleştirilmiştir. Püskürtme testleri için 5 farklı orifis çapına (Ø1.0 mm, Ø1.2 mm, Ø1.6 mm, Ø2.0 mm ve Ø2.4 mm) sahip konik hüzmeli meme plakaları kullanılmıştır. Püskürtme denemeleri sabit 8 bar işletme basıncında ve 55 cm püskürtme yüksekliğinde yapılmıştır. Denemeler her bir orifis çapı için 40 tekerrürlü yürütülmüştür. Deneme sonucunda püskürtme paterniyle ilgili çarpıklık, basıklık, püskürtme paterninin varyasyon katsayısı (%CV), farklı meme aralıklarında (25 cm, 30 cm, 35cm, 40 cm, 45 cm ve 50 cm) enine dağılım düzgünlüğü (%CV), meme hüzme açısı ve meme örtme genişliği değişkenleri belirlenmiştir. Araştırma sonuçlarına göre; paternatör prototipinde yapılan tüm püskürtme paterni testleri pratik bir şekilde yapılmış ve değerler başarılı bir şekilde alınmıştır. Hüzme açısı ortalamaları 78.1°-93.8° aralığında belirlenmiştir. Meme orifis çapı arttıkça püskürtme paterninin çarpıklığı azalmıştır. Püskürtme paternleri genelde normale göre üstten basık formda oluşmuştur. Ofisi çapı Ø1.0 mm ve Ø1.2 mm olan meme plakalarının en düşük CV ortalaması; 25 cm ve 30 cm meme aralıklarında elde edilmiştir. Büyük orifis çaplı memelerde optimum bum yüksekliğinin belirlenmesi gerekmektedir.
The structure of rural households’ income in North Macedonia - A case study in Polog and Pelagonija
Authors: Gjosheva Kovachevikj Marija , Dimitrov Lazo , Popovska Stojanov Despina
Published: October 2023

Contemporary trends in rural economic development go beyond the concept that agriculture and food production are the only functions of the rural economy and move towards a broader concept that covers all resources in the rural area, including non-agricultural activities. This paper examines rural households’ economic diversification focusing on their income structure and its impact on their well-being. The paper is based on а questionnaire survey conducted in the year 2018, through direct visits and interviews of 140 rural households from two statistical regions in North Macedonia, Pelagonija and Polog, with carefully designed study’s sample selection methodology to capture the household characteristics. The household income structure is measured as net incomes from all on-farm and off-farm activities and other financial transfers for one calendar year. The analysis has shown that the households which have only one type of income source (I. households with on-farm incomes only from agricultural activities, II. households with on-farm incomes only from nonagricultural activities) have much lower financial success than ones with mixed income sources, while non-agricultural rural households achieve the least success. In addition, households with mixed income sources, including incomes from agriculture, have better financial results than other households with mixed income sources, which do not comprise agricultural incomes. Hence, the challenge for policymakers is to identify the best mechanism to promote rural households’ economic portfolio, with a well-balanced synergy between agricultural and non-agricultural activities, based on agriculture at the centre of rural development, as complementary engines to tackle rural poverty and provide food security.
Consumer attitudes about purchasing and consuming vegetables in the Republic of Srpska
Authors: Ostojić Aleksandar , Vračar Luka , Jalić Nemanja
Published: October 2023

The main goal of the research was to investigate the consumer attitudes when buying and consuming vegetables. Primary data collection was carried out in the second half of 2022. A survey of 100 people was conducted with a structured questionnaire that included socio-demographic questions and questions that were directly related to attitudes towards buying and consuming vegetables. To calculate and determine the associations between certain characteristics of the sample, the Chi-Square (χ2) test was also applied. The results showed that vegetables are most often bought in supermarkets (49%) and green markets (25%). According to the results, 70% of consumers spend less than 100 BAM per month on buying vegetables and 30% more than 100 BAM. The most important factors when buying vegetables are freshness, quality, smell and taste, and the origin of a product. The size and appearance of vegetables and the vicinity of the selling place are less important factors. Consumers with a lower income spend less on vegetables on a monthly basis. The monthly expenditure on vegetables and the frequency of purchase are interconnected. Respondents whose households spend less on vegetables buy them more often in mini and supermarkets, while those who spend more buy them more often at the green market. Male respondents think that their households spend less on vegetables compared to the opinion of female respondents.
σ28-dependent small RNA regulation of flagella biosynthesis
Authors: Melamed Sahar , Zhang Aixia , Jarnik Michal , Mills Joshua , Silverman Aviezer , Zhang Hongen , Storz Gisela
Published: October 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional regulation. Small RNAs (sRNAs) are widespread posttranscriptional regulators, most base pairing with mRNAs to affect their stability and/or translation. Here we describe four UTR-derived sRNAs (UhpU, MotR, FliX and FlgO) whose expression is controlled by the flagella sigma factor σ
28
(
fliA
) in
Escherichia coli
. Interestingly, the four sRNAs have varied effects on flagellin protein levels, flagella number and cell motility. UhpU, corresponding to the 3’ UTR of a metabolic gene, likely has hundreds of targets including a transcriptional regulator at the top flagella regulatory cascade connecting metabolism and flagella synthesis. Unlike most sRNAs, MotR and FliX base pair within the coding sequences of target mRNAs and act on ribosomal protein mRNAs connecting ribosome production and flagella synthesis. The study shows how sRNA-mediated regulation can overlay a complex network enabling nuanced control of flagella synthesis.
Structural basis for preservation of a subset of Topologically Associating Domains in Interphase Chromosomes upon cohesin depletion
Authors: Jeong Davin , Shi Guang , Li Xin , Thirumalai D.
Published: October 2023

Compartment formation in interphase chromosomes is a result of spatial segregation between eu- and heterochromatin on a few mega base pairs (Mbp) scale. On the sub-Mbp scales, Topologically Associating Domains (TADs) appear as interacting domains along the diagonal in the Hi-C contact map (CM). Hi-C experiments showed that most of the TADs vanish upon deleting cohesin, while the compartment structure is maintained and is even enhanced. However, closer inspection of the data reveals that a non-negligible fraction of TADs is preserved (P-TADs) after cohesin loss. Imaging experiments show that, at the single-cell level, TAD-like structures are present even without cohesin. To provide a structural basis for these findings, we used polymer simulations to show that certain TADs with epigenetic mismatches across their boundaries survive after depletion of loops. More importantly, the three-dimensional structures show that many of the P-TADs have sharp physical boundaries. Informed by the simulations, we analyzed the Hi-C maps (with and without cohesin) in mouse liver and HCT-116, which affirmed that epigenetic mismatches and physical boundaries (calculated using the 3D structures) explain the origin of the P-TADs. Single-cell structures, calculated from using only the Hi-C map without
any parameters
, display TAD-like features in the absence of cohesin that are remarkably similar to the findings in imaging experiments, thus providing a cross validation of the computations. Some P-TADs, with physical boundaries, are relevant to the retention of enhancer-promoter/promoter-promoter interactions. Overall, our study shows that preservation of a subset of TADs upon removing cohesin is a robust phenomenon that is valid across multiple cell lines.
Exploration of Mechanisms of Drug Resistance in a Microfluidic Device and Patient Tissues
Authors: Lim Wanyoung , Hwang Inwoo , Zhang Jiande , Chen Zhenzhong , Han Jeonghun , Jeon Jaehyung , Koo Bon-Kyoung , Kim Sangmin , Lee Jeong Eon , Pienta Kenneth J. , Amend Sarah R. , Austin Robert H. , Ahn Jee-Yin , Park Sungsu
Published: October 2023

Chemoresistance is a major cause of treatment failure in many cancers. However, the life cycle of cancer cells as they respond to and survive environmental and therapeutic stress is understudied. In this study, we utilized a microfluidic device to induce the development of doxorubicin-resistant (DOXR) cells from triple negative breast cancer (TNBC) cells within 11 days by generating gradients of DOX and medium.
In vivo
chemoresistant xenograft models, an unbiased genome-wide transcriptome analysis, and a patient data/tissue analysis all showed that chemoresistance arose from failed epigenetic control of the nuclear protein-1 (NUPR1)/histone deacetylase 11 (HDAC11) axis, and high Nupr1 expression correlated with poor clinical outcomes. These results suggest that the chip can rapidly induce resistant cells that increase tumor heterogeneity and chemoresistance, highlighting the need for further studies on the epigenetic control of the NUPR1/HDAC11 axis in TNBC.
Glutamatergic Supramammillary Nucleus Neurons Respond to Threatening Stressors and Promote Active Coping
Authors: Escobedo Abraham , Holloway Salli-Ann , Votoupal Megan , Cone Aaron L , Skelton Hannah E , Legaria Alex A. , Ndiokho Imeh , Floyd Tasheia , Kravitz Alexxai V. , Bruchas Michael R. , Norris Aaron J.
Published: October 2023

Threat-response neural circuits are conserved across species and play roles in normal behavior and psychiatric diseases. Maladaptive changes in these neural circuits contribute to stress, mood, and anxiety disorders. Active coping in response to stressors is a psychosocial factor associated with resilience against stress induced mood and anxiety disorders. The neural circuitry underlying active coping is poorly understood, but the functioning of these circuits could be key for overcoming anxiety and related disorders. The supramammillary nucleus (SuM) has been suggested to be engaged by threat. SuM has many projections and contains poorly understood diversity of populations. We identified a unique population of glutamatergic SuM neurons (SuM
VGLUT2+
::POA) based on projection to the POA and found SuM
VGLUT2+
::POA neurons have extensive arborizations. SuM
VGLUT2+
::POA neurons project to brain areas that mediate various features of the stress and threat responses including the paraventricular nucleus thalamus (PVT), periaqueductal gray (PAG), and the habenula (Hb). Thus, SuM
VGLUT2+
::POA neurons are positioned as hubs connecting to areas implicated regulating stress responses. Here we report SuM
VGLUT2+
::POA neurons are recruited by diverse threatening stressors and recruitment of SuM
VGLUT2+
::POA neurons correlated with active coping behaviors. We found that selective photoactivation of the SuM
VGLUT2+
::POA population drove aversion but not anxiety like behaviors. Activation of SuM
VGLUT2+
::POA neurons in the absence of acute stressors evoked active coping behaviors and drove goal directed behavior. Also, activation of SuM
VGLUT2+
::POA neurons was sufficient to convert passive coping strategies to active behaviors during acute stress. These findings establish a new node in stress response circuitry that has projections to many brain areas and evokes flexible active coping behaviors and offers new opportunities for furthering our neurobiological understanding of stress.
A 2D image 3D reconstruction function adaptive denoising algorithm
Authors: Wang Feng , Ni Weichuan , Liu Shaojiang , Xu Zhiming , Qiu Zemin , Wan Zhiping
Published: October 2023

To address the issue of image denoising algorithms blurring image details during the denoising process, we propose an adaptive denoising algorithm for the 3D reconstruction of 2D images. This algorithm takes into account the inherent visual characteristics of human eyes and divides the image into regions based on the entropy value of each region. The background region is subject to threshold denoising, while the target region undergoes processing using an adversarial generative network. This network effectively handles 2D target images with noise and generates a 3D model of the target. The proposed algorithm aims to enhance the noise immunity of 2D images during the 3D reconstruction process and ensure that the constructed 3D target model better preserves the original image’s detailed information. Through experimental testing on 2D images and real pedestrian videos contaminated with noise, our algorithm demonstrates stable preservation of image details. The reconstruction effect is evaluated in terms of noise reduction and the fidelity of the 3D model to the original target. The results show an average noise reduction exceeding 95% while effectively retaining most of the target’s feature information in the original image. In summary, our proposed adaptive denoising algorithm improves the 3D reconstruction process by preserving image details that are often compromised by conventional denoising techniques. This has significant implications for enhancing image quality and maintaining target information fidelity in 3D models, providing a promising approach for addressing the challenges associated with noise reduction in 2D images during 3D reconstruction.
How young people perceive brands with purpose through social networks in Spain
Authors: Sebastián-Morillas Ana , Martín Soladana Irene , Jorge Clemente Mediavilla Jorge Clemente
Published: October 2023

This article analyzes how brand purpose can influence the way brands develop their communication strategies to reach young people and the importance given to it to change the world. A self-administered online questionnaire was sent to a sample of 500 students from Spanish faculties of Communication Sciences to find out how important brand purpose is to their communication. The results show that brand purpose is important and should be reflected in brands’ communication strategies so that young people buy them in the future, as the vast majority of them want a better society. It can also be said that in today’s society, brands can use their communication strategies as a means to improve the world. However, many young people do not know what brand purpose means and do not rule out buying products that do not meet the brand’s purpose. Therefore, brands need to put more emphasis on developing clear brand purpose strategies to reach more young people and change society to make the world a better place.
Plataformas #paraservir. La estrategia digital de la Unidad Militar de Emergencias (UME) como muestra del potencial de las redes sociales ante situaciones de emergencia y protección civil
Authors: Martín García Alberto , Buitrago Álex , Martín García Noemí
Published: October 2023

La Unidad Militar de Emergencias (UME) actúa en situaciones de catástrofe y emergencia principalmente en España. La profesionalización de su comunicación ha incrementado el alcance y la comprensión de sus intervenciones. Partiendo de un análisis de contenido de carácter cualitativo en las plataformas Facebook, Twitter e Instagram (meses de junio y diciembre de 2022), profundizamos en cómo la unidad expone sus contenidos en las redes sociales. De los resultados se desprenden tres conclusiones principales: a) la comunicación en Facebook, Twitter e Instagram está planificada con solvencia, se apoya en elementos visuales y textuales coherentes, y humaniza a los profesionales que trabajan en la unidad; b) la dinámica de contenidos varía sustancialmente cuando hay una intervención de emergencia, generando un relato permanente que ayuda a la sociedad a estar informada desde el propio campo de actuación, y c) la reacción de los usuarios es positiva y apenas existen críticas negativas hacia la UME.
Discurso performativo y mentira política durante el proceso de paz con las FARC
Authors: Codina Mónica , Novoa-Jaso María Fernanda , Marín Cáceres Luisa Fernanda
Published: October 2023

Este artículo analiza la línea argumentativa del presidente Juan Manuel Santos durante el proceso de paz abierto con las FARC en Colombia para determinar en qué medida su discurso presenta un carácter performativo (Austin,1962) y hasta qué punto presenta rasgos característicos de la mentira política (Arendt, 1993, 2003; Bok, 1978). Para ello, se sigue una metodología cualitativa de nivel explicativodescriptivo del discurso político, realizando un análisis de las 33 declaraciones oficiales relativas al proceso de paz realizadas por el presidente entre 2012 y 2016, publicadas en el canal oficial de YouTube de la Presidencia de la República de Colombia. El análisis de estas declaraciones permite determinar siete enunciados con los que el presidente crea el marco comunicativo con el que trata de influir en la opinión pública para ganar el apoyo de la sociedad colombiana y de las FARC. En segundo lugar, tomando como referencia la obra de Austin (1962), el análisis de los recursos verbales utilizados por el presidente revela la naturaleza eminentemente performativa de estas declaraciones. Estas tienen carácter pragmático y no solo semántico, en la medida en la que ejecutan la acción y el compromiso presidencial de abrir un proceso que conduzca a la paz. Finalmente, los resultados revelan la ambivalencia de algunos enunciados que se alejan de la verdad fáctica, poniendo de manifiesto la existencia de algunos rasgos típicos de la mentira política.
¿Son las series españolas diversas? Un análisis sobre la inclusión en las plataformas
Authors: Martín García Teresa , Marcos Ramos María , Angulo-Brunet Ariadna
Published: October 2023

Este estudio analiza las principales características de los personajes de las series españolas que se emiten en las plataformas de streaming desde la óptica de la diversidad, poniendo el foco en cuestiones de género, edad, nacionalidad, etnia, orientación sexual y diversidad funcional. En los últimos años, la expansión de este tipo de plataformas ha transformado los niveles de representación e inclusión en sus contenidos audiovisuales que, incluso, son publicitados como diversos. En este artículo se busca comprobar si la representación que ofrecen estos productos es similar a la real o, por el contrario, la diversidad es solo una estrategia de marketing para atraer a los servicios de suscripción o para realizar lo que se denomina diversity washing, esto es, utilizar la diversidad para cubrir cuotas, pero sin considerarla verdaderamente. Para poder determinar los principales rasgos de representación de los personajes, se ha realizado un análisis de contenido de 38 series emitidas en plataformas españolas en 2021, con un total de 749 personajes. Los resultados indican que aún no puede hablarse de una representación diversa en las plataformas de streaming; sigue existiendo un predominio masculino en los papeles protagónicos en un contexto de heteronormatividad, y hay franjas de edad infrarrepresentadas, como la vejez. Asimismo, aunque se haya aumentado la presencia de personajes de diferentes orígenes geográficos y etnias, la gran mayoría de los personajes son caucásicos. Cabe destacar que apenas hay personajes con diversidad funcional en este tipo de ficción seriada.
Relaciones intermediales en el cine mexicano: los números musicales y el espacio teatral
Authors: Flores Silvana
Published: October 2023

Estudiaremos fragmentos de films mexicanos del período clásico, en los que se evidencian nexos intermediales entre el cine y el espacio teatral. Destacaremos una difuminación de límites entre el espacio teatral y el cinematográfico en los escenarios filmados en dichas películas, con base en sus estrategias narrativo-espectaculares. Seleccionaremos secuencias de canto o baile en las que estos intercambios se hicieron patentes, en las películas Canto a mi tierra (México canta, José Bohr, 1938), Aventurera (Alberto Gout, 1950) y Aventura en Río (Alberto Gout, 1953), distinguiendo las especificidades de este fenómeno. El objetivo será determinar las modalidades de representación que se adoptan en los escenarios en los que dichos espectáculos fueron desplegados. Utilizaremos una metodología comparada determinando sus procedimientos por medio del trabajo sobre la puesta en escena. Evidenciaremos una tendencia a la parcelación del espacio teatral manifiesta en los números musicales. Esto nos guiará a destacar los vínculos intermediales entre cine y teatro, aludiendo a la conexión entre medios expresivos, en el contexto de la emergencia de las nuevas tecnologías que aparecieron en la primera mitad del siglo XX.
As vacinas contra a Covid-19 no TikTok no Brasil
Authors: Pereira Costa Ben-Hur Bernard , Herculano Maia Lídia Raquel , dos Santos Júnior Marcelo Alves , Thaiane Oliveira Thaiane , Massarani Luisa
Published: October 2023

Neste artigo, estudamos a produção de vídeos sobre as vacinas no TikTok no Brasil. A partir de hashtags associadas à vacina, identificamos 612 vídeos que abordaram a questão vacinal nessa plataforma no período de maio de 2020 a setembro de 2022. Por meio de análise temática e análise de conteúdo, examinamos os temas, posicionamentos, formas expressivas, atores legitimados e recursos sonoros e visuais presentes na produção de conteúdo sobre as vacinas nessa plataforma. A partir da análise, verificamos um posicionamento positivo em pouco mais da metade dos vídeos a respeito das vacinas, com alta presença também de posições neutras ou ambíguas sobre o assunto. Observamos ainda o uso do TikTok para o compartilhamento de experiências pessoais com a vacinação, esquetes sobre supostos efeitos colaterais das vacinas, expressões de comemoração pelo início da imunização e informações sobre a eficácia e a implementação dos imunizantes. Identificamos também uma politização do conteúdo sobre vacinação contra a COVID-19 na plataforma, refletindo o cenário de disputas políticas que marcou a pandemia no Brasil. Concluímos que o TikTok tem sido utilizado como uma ferramenta para expressão de experiências e percepções quanto à vacinação, mas também para a circulação de conteúdos que utilizam um tom humorístico na abordagem do tema, podendo resultar no espalhamento de temores e percepções negativas em relação às vacinas.
Construction management using ranking effective factors on the construction cost overrun via fuzzy DANP and delphi technique
Authors: Marzangoushi Ali , Mirjalili Alireza , Dehnavi Hassan Dehghan
Published: October 2023

The primary objective of this paper is to examine the impact of several effective factors on the construction cost overrun projects which are experienced explicitly by developing countries. In this regard, a hierarchical analysis technique is employed for conducting descriptive and survey research to comprehensively evaluate the effective factors of the construction cost overrun in Yazd city in Iran. The statistical population consists of 150 members from the managers, officials, and contractors involved professionally in construction projects. The results show that the managerial factors have the highest score amongst the investigated effective criteria and the administrative factors and environmental factors come respectively at the second and third priority. Since management is the key element in construction projects, the cost overrun can be reduced by establishing new managerial approaches and redirecting the managerial criteria to a higher performance level.
Effect of Educational Intervention based on Pender’s Health Promotion Model on Selfcare Behaviours of Patients with Colorectal Cancer undergoing Chemotherapy: A Quasi-experimental Study
Authors: Zenoozadeh Vahideh , Payandeh Abolfazl , Seraji Maryam
Published: October 2023

Introduction: Colorectal cancer is the third most common malignancy in Iran. Self-care is one of the most effective non pharmacological interventions for controlling the effects of the disease and the side-effects of drugs. An educational intervention based on Pender’s health promotion model, which predicts health behaviours and self-care, can be implemented. Aim: To investigate the effect of an educational intervention based on Pender’s health promotion model on improving selfcare behaviours among patients with colorectal cancer. Materials and Methods: This quasi-experimental study was conducted at Omid and Imam Reza Hospitals in Mashhad, Iran from June to August 2021. A total of 160 participants were divided into two groups: the experimental group (n=80) and the control group (n=80). The experimental group received four self-care education sessions (two sessions by a nurse and two sessions by peers), while the control group received no intervention. Data were collected using a questionnaire before, immediately after, and three months after the educational intervention. Statistical analysis was performed using independent samples t-test and Repeated Measures Analysis of Variance (RMANOVA). Results: The study included 103 male patients (64.4%) and 57 female patients (35.6%). At one month and three months after the intervention, the scores for awareness, attitude, behaviour, and the constructs of Pender’s health promotion model (self-efficacy, perceived social support, perceived benefits, perceived barriers, perceived emotions) significantly increased in the intervention group compared to the control group (p-value<0.001). Conclusion: The findings of this study indicate that the educational intervention based on Pender’s health promotion model effectively promotes self-care behaviours among patients with colorectal cancer.
Effect of Isotonic Exercise on Cardiovascular Parameters in Medical Students with Different Body Mass Indices: A Cross-sectional Study
Authors: Siraj Sana , Ravella Anitha , Yasmeen Nikhat , Siddiqui Abdul Raoof Omer , Rahman Javeria Amatul
Published: October 2023

Introduction: Obesity is a known risk factor for hypertension. Baseline Heart Rate (HR) and blood pressure are known to scale linearly with Body Mass Index (BMI) values. Recent studies have reported an exaggerated acute response of blood pressure and HR to exercise. Aim: To assess the effect of isotonic exercise on cardiovascular parameters among individuals with different body mass indices in students at Osmania Medical College and look for any association between BMI and cardiovascular responses to isotonic exercise. Materials and Methods: A cross-sectional study was conducted in the Department of Physiology at Osmania Medical College, Hyderabad, Telangana, India, from January 2022 to December 2023, involving 100 healthy individuals with different body mass indices in the age group of 17 years-30 years. The subjects were divided into four groups based on their BMI. Baseline HR, Systolic Blood Pressure (SBP), and Diastolic Blood Pressure (DBP) were measured for all participants. Subsequently, the participants performed isotonic exercise for three minutes. Post-exercise HR, SBP, and DBP were measured immediately. One-way ANOVA was used to determine the significance of HR, SBP, DBP, Mean Arterial Pressure (MAP), and Pulse Pressure (PP) among the different BMI groups. A p-value of <0.05 was considered statistically significant. Results: A total of 100 subjects (28 males, 72 females) with a mean age of 18.64±0.92 years participated in the study. Significant differences were observed in pre-exercise HR (p=0.0002), SBP, DBP, and MAP (p<0.001), and post-exercise HR, SBP, DBP, and MAP (p<0.001) among the different BMI groups. Overweight and obese individuals showed an increased tendency for an exaggerated increase in HR. Changes in PP and MAP, affected by a combination of SBP and DBP, also showed statistical significance. Furthermore, there was an increased tendency for an exaggerated increase in blood pressure in the overweight and obese BMI groups. Conclusion: Individuals with higher BMI exhibit exaggerated increases in SBP, Mean and PP, as well as HR. Additionally, obese individuals demonstrated a significant elevation in DBP. The response of blood pressure and HR after exercise in overweight/obese individuals suggests a higher risk of developing hypertension and other cardiovascular diseases.
Autonomic Functions in Patients with Allergic Rhinitis: A Cross-sectional Observational Study
Authors: Gupta Himanshu , Shukla Jyotsna , Gupta Varsha , Saini Abhishek
Published: October 2023

Introduction: Even after decades of the development of lowcost and effective antibiotics, puerperal infections remain an important cause of preventable maternal morbidity and mortality. Aim: The aim of the present study was to determine the risk factors, morbidity, and mortality associated with puerperal infections. Materials and Methods: A retrospective study was conducted from March 2021 to October 2021, at the Obstetrics and Gynaecology Department of Gandhi Hospital in Telangana, India. The study included all women who delivered in this hospital and were referred within 42 days after delivery with fever and any of the following symptoms: pain abdomen, malodorous lochia, abdominal distention, subinvolution of the uterus, pelvic abscess, peritonitis, any system/organ failure, or shock. Various risk factors such as age, parity, socioeconomic status (according to the modified Kuppuswamy scale), BMI, rupture of membranes, mode of delivery, and comorbidities associated with puerperal infection were assessed. Complications following puerperal infection were also studied. Data analysis was performed using SPSS version 23.0, and the results were presented in frequency and percentages of categorical variables. Results: During the study period, there were 161 cases of puerperal infection. The majority of cases were between the age group of 26-30 years, constituting 72 (44.7%) cases. Among them, 86 (53.4%) cases were multiparous, 50 (31%) cases were primiparous, 10 (6.2%) cases were second gravida, and 15 (9.3%) cases were third gravida. Lower middle-class women accounted for 67 (41.6%) cases, and 85 (52.7%) cases were in the overweight range. Prolonged premature rupture of membranes for more than 24 hours was observed in 78 (48.4%) cases. Caesarean section was the mode of delivery for 90 (56%) cases of puerperal infection cases. The most commonly associated comorbidities were anaemia in 63 (39.1%) cases, severe preeclampsia in 47 (29.1%) cases, abruption in 31 (19.2%) cases, and diabetes in 20 (12.4%) cases. Prolonged hospital stay was observed in 144 (89.4%) cases, wound gaping in 26 (16.1%) cases, and disseminated intravascular coagulation in 24 (14.9%) cases. A total of 31 (19.2%) cases of women succumbed, mostly due to multi-organ failure. Conclusion: Early diagnosis, proper ICU facilities at all levels of healthcare, timely referral to tertiary facilities, health education, and strict aseptic measures would be crucial in tackling this menace.