bluuebunny/crossref_metadata_2025 huggingface dataset:
Root CT Segmentation Using Incremental Learning Methodology on Improved Multiple Resolution Images
Authors: Geetha K.
Published: December 2021

The real-time issue of reliability segmenting root structure while using X-Ray Computed Tomography (CT) images is addressed in this work. A deep learning approach is proposed using a novel framework, involving decoders and encoders. The encoders-decoders framework is useful to improve multiple resolution by means of upsampling and downsampling images. The methodology of the work is enhanced by incorporating network branches with individual tasks using low-resolution context information and high-resolution segmentation. In large volumetric images, it is possible to resolve small root details by implementing a memory efficient system, resulting in the formation of a complete network. The proposed work, recent image analysis tool developed for root CT segmented is compared with several other previously existing methodology and it is found that this methodology is more efficient. Quantitatively and qualitatively, it is found that a multiresolution approach provides high accuracy in a shallower network with a large receptive field or deep network in a small receptive field. An incremental learning approach is also embedded to enhance the performance of the system. Moreover, it is also capable of detecting fine and large root materials in the entire volume. The proposed work is fully automated and doesn’t require user interaction.
Resources of modern radiation diagnostics of sarcoidosis (review)
Authors: Ignat’eva E. A.
Published: December 2021

Introduction.Sarcoidosis is a significant social and medical problem. Diagnosis is based on consistency of the clinical picture, histological evidence of granulomatous inflammation, exclusion of alternative diseases, and evidence of systemic involvement. There is no “gold” diagnostic standard for sarcoidosis. Aim.Review of the latest world literature data on the possibilities of modern radiation diagnosis of sarcoidosis. Materials and methods.The review summarizes data from literature published mainly over the past five years in PubMed and eLibrary. Earlier publications were also included as necessary. Results.In the literature review, modern medical imaging methods used to diagnose sarcoidosis, which in some cases can avoid biopsy, are considered. First of all, these are X-ray methods. Today, high-resolution multispiral computed tomography with three-dimensional imaging, as the method with the highest sensitivity, plays a decisive role in the diagnosis and monitoring of sarcoidosis. The use of magnetic resonance imaging and low-dose computed tomography is not well understood in patients with sarcoidosis. Quantitative computed tomography and radiomics techniques have only been partially tested in sarcoidosis. Conclusion.The imaging of sarcoidosis is the subject of a large number of publications that provide detailed descriptions of X-ray and computed tomography techniques. Nevertheless, despite the introduction of new computerized tools for the analysis of chest imaging, traditional X-ray techniques still remain an important role in both the diagnostic and prognostic assessment of changes characteristic of sarcoidosis
Respiratory virus monitoring in patients with community-acquired pneumonia during COVID-19 pandemic in Khabarovsk in 2020
Authors: Butakova L. V. , Sapega E. Yu. , Trotsenko O. E. , Balakhontseva L. A. , Prisyazhnyuk E. N. , Savosina L. V.
Published: December 2021

Introduction. Emergence and spread of new coronavirus SARS-CoV-2 among population of the Khabarovsk krai influenced the growth of reported cases of community-acquired pneumonia in year 2020. Aim. To determine proportion of other respiratory viruses in development of viral pneumonia epidemic process in the Khabarovsk city in year 2020 during COVID-19 pandemic. Materials and methods. Sputum of 346 patients with community-acquired pneumonia that were hospitalized with suspected diagnosis of COVID-19 was analyzed during year 2020 in Khabarovsk city. Identification of viral agents was performed via real-time reverse-transcriptase polymerase chain reaction. Results. SARSCOV-2 RNA was identified in 183 (52.9%) out of 346 patients. Among other respiratory viruses parainfluenza virus type 3 and rhinoviruses were dominant mostly in SARS-CoV-2 negative examined people. It should be noted that etiology of pneumonia was identified only in 12.9% of all cases in this group (163 people). Co-infection with SARS-CoV-2 and other respiratory viruses such as parainfluenza virus type 3 virus, other coronaviruses and adenovirus was detected only in 2.2% of the cases. Conclusion. Low level of respiratory viruses detection in sputum can be caused by poor technique of sample collection in the hospital, disruption of storage and transportation conditions as well as development of secondary bacterial infection in certain patients. In order to evaluate influence of other respiratory viruses on the course of COVID-19 with underlying coinfection further investigation including analysis of patients’ clinical data is needed.
Regression analysis to estimate the response of the respiratory organs to exposure of air microtoxicants in chronic obstructive pulmonary disease
Authors: Vitkina T. I. , Veremchuk L. V. , Gvozdenko T. A. , Mineeva E. E.
Published: December 2021

Inroduction. The assessment of the respiratory system is of particular importance in the context of increasing impact of anthropogenic factors on human health. Aim. Evaluation the response of the lung function indices to the effects of micro-suspensions and toxic metals in patients with chronic obstructive pulmonary disease (COPD), using regression models. Materials and methods. The study involved 60 patients with stable mild-to-moderate COPD and 30 healthy people (the control group). The analysis of lung function was carried out by spirometry and body plethysmography. Arterial oxygen saturation (SaO2 ) was measured by pulse oximetry. Exhaled CO2 concentration and blood carboxyhemoglobin (COHb%) concentration were assessed using a portable analyzer MicroCO Meter. The pollution of the city atmosphere was assessed by aerosol suspensions of solid particles in the areas of residence of the examined patients. Fractional composition of suspended particles (0-1, 1-10, 10-50, 50-100, 100-400, 400-700,> 700 μm; %) were analyzed in the areas of residence of the examined patients. Toxic metal (Pb, Cr, Mn, Fe, Co, Ni, Cu, Zn; μg/L) levels in the air samples were determined. The statistical module "Multiple regression" was used for assessing the response of functional parameters of the respiratory system. Results. The analysis of one-factor and multi-factor regression models made it possible to identify both trigger factors of dust and technogenic air pollution and the synergistic effect of the influence of dominant factors. It has been shown that multifactorial reactions to technogenic impact manifest as altered blood oxygen saturation and carboxyhemoglobin level and thereby contribute to the development of respiratory failure. Conclusion. Patients with COPD exhibited increased bronchial resistance to the effect of the trigger factor (Pb – 1 hazard class) associated with high motorization of the city. The response of pulmonary gas exchange (SaO2 ) to Pb in the control group indicates prolonged exposure to toxic metals can cause developing respiratory failure even in the healthy population of the city.
Helikopter Anababalık ve Gençler Üzerindeki Gelişimsel Etkileri
Authors: GÜÇLÜ Cansu Hazal , ÇOK Figen
Published: December 2021

Bu çalışmanın amacı son zamanlarda literatürde giderek daha fazla yer alan helikopter anababalık olgusunu özellikle anababa genç ilişkilerinde de görülmesi çerçevesinde gözden geçirmek ve helikopter anababalığın gençlerin ruh sağlığına etkileri konusunda bir değerlendirmede bulunmaktır. Bu çalışmada helikopter anababalığın kavramsal olarak tanımlanması, helikopter anababalığa katkıda bulunan nedenler, içinde bulunduğumuz tarihsel dönem ve kuşak kavramları değerlendirilerek ele alınmakta ve helikopter anababalığın sonuçlarına ilişkin araştırmalar farklı psikolojik boyutlarda (özerklik, bağlılık, kaygı, öz-yeterlik vb.) paylaşılmaktadır. Literatürde helikopter anababalık davranışlarının çocuklarının gelişimi açısından çoğunlukla olumsuz sonuçlar ortaya koyduğu görülmektedir. Helikopter anababaların çocuklarının akademik, sosyal ve kişisel yaşantılarına ilgileri ve müdahaleleri, çocuklarını yaşamın getirilerine karşı hazırlıksız olmalarına neden olup, farklı olumsuz psikososyal sonuçları da beraberinde getirebilmektedir.
MA’BURA KAMPUNG: RITUAL TRADISIONAL PADA MASYARAKAT BATETANGNGA DI KABUPATEN POEWALI MANDAR PROVINSI SULAWESI BARAT
Authors: Hafid Abdul
Published: December 2021

Tulisan ini bertujuan untuk mendekripsikan tentang tradisi ritual Mabbura Kampung, yang merupakan salah satu tradisi ritual yang dilakukan pada masyarakat Suku Pattae tepatnya Dusun Baruga dan Dusun Passembaran di Kabupaten Polewali Mandar Sulawesi Barat. Tulisan ini menggunakan metode kualitatif dengan pendekatan deskriptif, dengan teknik pengumpulan data melalui observasi (pengamatan langsung terhadap berbagai aktivitas dan perilaku pada masyarakat Suku Pattae di Desa Batetangnga), wawancara mendalam terhadap tokoh masyarakat, budayawan, pelaku ritual dan pemerintah setempat serta dokumentasi. Tradisi ritual Mabbura Kampung ini, mencerminkan karakter dan jati diri masyarakat Suku Pattae di Desa Batetangnga sehingga perlu dikaji dalam upaya melestarikan budaya lokal, sebagai bagian dari kekayaan budaya bangsa. Dari hasil penelitian ini diketahui, bahwa pelaksanaan tradisi ritual Mabbura Kampung merupakan warisan nenek moyang terdahulu yang diyakini sebagai pencucian diri atau tolak bala’ dari berbagai gangguan bencana alam, baik gangguan tanaman, gangguan di sungai maupun gangguan wabah penyakit yang dapat membahayakan kehidupan masyarakat pendukungnya. Tradisi ritual Mabbura Kampung  tersebut hingga saat ini masih tetap bertahan dan dilakukan secara turun temurun oleh masyarakat pendukungnya yang bermukim di Desa Batetangnga dan masyarakar Suku Pattae pada umunya. Tradisi ritual ini dipimpin oleh dua orang, yaitu  sando banua baine (dukun kampung perempuan), dan seorang Imam kampung, dan  kedua pemimipin ritual ini  mempunyai tugas masing-masing.
Features of bioaccumulation and toxic effects of copper (II) oxide nanoparticles under the oral route of intake into the body
Authors: Zemlyanova M. A. , Stepankov M. S. , Ignatova A. M.
Published: December 2021

Introduction. Active use in various spheres of economic activity and the large-scale nature of production determine the relevance of studying the effects of copper (II) oxide nanoparticles (CuO NPs) on the body during the oral route of intake. Material and methods. Particle size was determined by scanning electron microscopy and dynamic laser light scattering; specific surface area - Brunauer, Emmett and Teller; total pore volume - Barrett, Joyner and Khalenda. Acute oral toxicity of CuO NPs was studied in Wistar rats in accordance with GOST 32644-2014, multiple oral toxicity was studied by the Lim method. After repeated exposure, the biochemical and hematological parameters of the blood, the concentration of copper in the organs, and pathomorphological changes in the tissues of the organs were determined. Results. The size of CuO NPs in the composition of the native powder was 45.86 nm, in the aqueous suspension - 307.40 nm, the specific surface area was 17.70 m2/g, and the total pore volume was 0.056 cm3/g. According to the results of a single oral exposure, the LD50 value was > 2000 mg / kg body weight, which corresponds to 3 (GOST 12.1.007-76) and 4 (GOST 32644-2014) hazard classes. With repeated oral exposure, an increase in the levels of activity of ALT, AST, ALP, LDH, amylase, AOA and MDA was noted; the relative number of segmented neutrophils is increased, the number of leukocytes is increased, the relative number of lymphocytes is reduced. The concentration of copper under the action of NPs increases in the lungs, liver, stomach, intestines, kidneys, brain and blood. Pathomorphological changes in the tissues of the liver, kidneys, stomach, small and large intestines and lungs were established. Conclusion. The results obtained prove the presence of toxic properties of CuO NPs and can be used in the development of preventive measures for workers and consumers in contact with products containing CuO NPs.
Methodological foundations for substantiating safe levels of exposure to artificial nanomaterials (for example, carbon nanotubes) (literature review)
Authors: Timerbulatova Gyuzel A. , Fatkhutdinova Liliya M.
Published: December 2021

Introduction. The unique physicochemical properties of carbon nanotubes allow them to be used in many fields. The global nanomaterials market is growing every year. An important step in introducing products to the domestic and world markets is to determine the safe exposure levels of CNTs. Establishing a corporate standard can serve as a preliminary stage before the approval of a state hygiene standard. Material and methods. The material for the analysis was the sources of information on the available standards for the content of CNTs in the air of the working area using information from regulatory agencies, research centers, CNT manufacturers, bibliographic and abstract databases Web of Science, Scopus, PubMed, RSCI. Results. A scheme for justifying safe levels of exposure to CNTs (corporate standard) has been developed, consisting of several stages: characterization of CNTs in the air at workplaces, selection of experimental doses of CNTs, preparation of CNT dispersions, and conducting toxicological and hygienic experiments. Justification of the corporate standard is carried out in in vitro and in vivo experiments. The planning of experiments should be carried out taking into account the target organ under the influence of CNT - the respiratory system. The recommended dose / concentration range for experiments should include doses / concentrations derived from calculated and literature data. A necessary step is to obtain homogeneous dispersions in which CNTs become bioavailable for biological systems. In vitro and in vivo experiments determine the level of exposure at which no harmful effect is observed and / or the lowest level of exposure at which there is a harmful effect on the cell culture / respiratory tract of animals. After the stage of substantiating the corporate standard, the enterprise should take measures for several years to adjust the corporate standard based on data from clinical and hygienic studies, during which the working conditions and health status of workers are monitored, and extended toxicological and hygienic studies. Conclusion. The presence of a corporate standard will allow the manufacturer of CNTs to carry out activities for the development and implementation of a production control program with the introduction of monitoring the air condition in the working area. The development of a corporate regulation can be seen as a preparatory stage before the establishment of a government regulation.
CONCEPTUAL APPROACHES TO BUILDING A COMPETITIVE METROPOLITAN AREA AND ITS HEALTH CARE SYSTEM
Authors: Korniychuk Oleksandr
Published: December 2021

Based on the generalization of France’s successful experience in metropolitan development, conceptual approaches to building a competitive metropolitan space in Ukraine and the health care system in three areas of attraction based on mutually agreed organizational, managerial and legal relations between metropolitan communities are substantiated. The metropolises of Ukraine include the cities of Kyiv, Dnipro, Odesa, Kharkiv, Lviv, and after the deoccupation - the city of Donetsk. A key problem in Ukraine is the lack of discussion of the institutional framework for the creation of metropolises according to EU standards for their integration into the European space on the basis of Ukraine's national interests. Such approaches should correspond to the fourth stage of reforming the administrative-territorial system at the regional level. This should apply to the formation of 13 metropolises in 25 regions on the basis of candidate cities - Zaporizhia, Vinnytsia, Kryvyi Rih, Sumy, Khmelnytsky, Uzhhorod, Cherkasy, Zhytomyr, Chernivtsi, Mykolaiv, Poltava, Chernihiv and Mariupol. It should be noted that the viability of metropolises is calculated by experts from the administrative, economic and social components. The strategy of the metropolitan health care system should include harmonization of prospects for the development of communities, districts and regions in the creation of an optimal system of primary health care, coordination of medical institutions in the hospital district and in the provision of tertiary care. It should be borne in mind that the metropolis forms 3 zones of influence: the first - within a radius of 15 km, the second up to 60 km, the third – up to 300 km. Each community provides primary care and is part of a hospital district that specializes in providing secondary care. In the third zone, the metropolis provides tertiary care with coverage of neighboring areas using the above approaches. The dynamics of morbidity of the population of the metropolis of Lviv and its metropolitan region has been studied. Promising actions of the Cabinet of Ministers of Ukraine and the National Academy of Sciences of Ukraine include preparation and holding of scientific-expert discussion of the draft law of Ukraine "On the formation of metropolises" with preliminary professional discussion and public involvement.
Pendekatan Psikososial, Intervensi Fisik, Dan Perilaku Kognitif Dalam Desain Pembelajaran Pendidikan Jasmani Bagi Anak Dengan Retardasi Mental
Authors: Kusmiyati Kusmiyati
Published: December 2021

Abstrak

Artikel ini merupakan sebuah tulisan yang mencoba membahas tentang: (1) pengertian anak retardasi mental, (2) kharakteristik anak retardasi mental, (3) kendala-kendala anak retardasi mental, serta (4) pendekatan pembelajaran yang dapat diaplikasikan untuk anak retardasi mental agar menjadi anak yang mandiri dalam hidupnya serta mampu bersosialisasi dan bermasyarakat. Retardasi mental atau keterbelakangan mental menunjuk pada penejelasan khusus kepada anak-anak yang memiliki tingkat intelegensi di bawah rata-rata. Terdapat beberapa istilah lain dari retardasi mental ini, seperti: mentally retarded, mental defective, dan lain sebagainya. Retadasi mental terjadi ditandai dengan adanya keterbelakangan mental yang dibawah rata-rata. Hal ini timbul selama periode pertumbuhan dan perkembangan anak sejak masih dalam kandungan. Keterbelakangan mental juga terjadi karena kelemahan dalam proses adaptasi dengan lingkungan selama masa tumbuh kembang.
“The SALC is mine!”: Supporting the Development of Learner Agency and Reconfiguration of Language Learning Environments Beyond the Classroom
Authors: Kashiwa Mayumi
Published: December 2021

This study explores the process of how a learner recognises the value of a Self-Access Learning Center (SALC) and takes charge of her own learning through self-reflection of her language learning environments beyond the classroom as well as her ideal future self-image as a motivational factor. A university student who majors in English drew a mind map as a tool to reflect on her learning activities beyond the classroom before and after engaging in various reflective activities. Employing a qualitative narrative case study approach, multiple data sources, which included two mind maps, written descriptions of them, and a follow-up semi-structured interview, were analysed from an ecological perspective. The findings show that the learner’s self-reflection on her learning environments beyond the classroom, as well as her stronger image of ideal future-self, guided her to step forward to take action to engage with the SALC to create a meaningful space to achieve her goals. The learner’s self-reflection on her engagement with the environments, strategic advice from her friends, and a clearer image of her ideal future self are seen as key factors for the development of her learner agency. The benefits of teachers including self-reflection during class time on learning beyond the classroom as an aid to develop learner agency are also outlined.
Faktor-Faktor Yang Mempengaruhi Minat Masyarakat Dalam Usaha Ternak Babi Di Desa Petak Bahandang
Authors: Daniel Susan
Published: December 2021

Pengembangan usaha peternakan harus disesuaikan dengan potensi daerah, ketersediaan pakan, dan kondisi sosial budaya untuk meningkatkan tingkat keberlanjutan dari usaha tersebut. Beternak babi merupakan salah satu usaha mata pencaharian masyarakat dalam memenuhi kebutuhan hidup dan menambah pendapatan rumah tangga. Penelitian ini dilaksanakan di Desa Petak Bahandang, Kabupaten Gunung Mas yang memiliki banyak peternak babi. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi minat masyarakat dalam usaha beternak babi. Penelitian ini merupakan penelitian lapangan dengan metode penelitian yang digunakan adalah metode deskriptif kualitatif. Hasil dari penelitian adalah terdapat beberapa faktor yang mempengaruhi minat masyarakat dalam beternak babi, yaitu kondisi lingkungan, modal awal, ketersediaan pakan, pemasaran, dan jaminan harga.
Identification of Dynamical Systems Through the Structure of Auto-regression With Exogenous Variable by Decreasing Gradient and Least Squares
Authors: Caiza Andres Morocho , Garces Erik F. Mendez , Mafla Gabriela , Guerra Joseph , Villalba Williams
Published: December 2021

In this article was made the identification of dynamic systems of first and second order more common in electronics such as low and high pass filters of the first order, pass-band filter and direct current motor through the structure of auto-regression with exogenous variable. The proposed dynamical systems are initially modeled by a continuous-time transfer function using physical laws. Subsequently, a step entry signal was applied and the data for the identification process was recorded in discrete time. The estimation of parameters was performed with the method of decreasing gradient and least squares. It was obtained as a result that the least squares method could not find a model for the first-order high-pass filter, but the decreasing grade method allowed to model all the proposed systems.
Experimental studies of the operation of a frameless building made of thin-gauge structural sections
Authors: Vedyakov I. I. , Solovyev D. V. , Smagin A. V.
Published: December 2021

Light metal structures (LMS) are widely spread in domestic construction industry. A promising direction for the development of LMS includes prefabricated shell structures made of thin-gauge structural sections. The scope and operating conditions of such structures are quite extensive. In this regard, the development of a competent engineering methodology for calculating buildings using thin-gauge structural sections is required. The present paper describes a method for a full-scale testing of a shell building fragment and provides the results of forces and deformations calculated using the experimental model. In addition, an approach to modeling and dimensioning of finite elements for the profiles under consideration is described. The comparative analysis of numerical data and experimental results is performed. The results of the study can be used both for developing recommendations and engineering methods for calculating similar shell buildings and for determining the actual operational scheme for units and elements of the considered structure.
Crack resistance of masonry walls
Authors: Ishchuk M. K. , Aizyatullin K. A.
Published: December 2021

Computer models used in the design calculation of masonry buildings sometimes fail to correctly take into account the stress-strain state of walls and assess the likelihood of cracks caused by the deformation differences of interacting walls.

Following the construction of a building, cracks can develop at wall intersections for several years. However, their repair is mostly ineffective until the total damping of masonry creep deformation.

Drawing on the analysis of conducted research and field data, the authors give recommendations on ensuring the crack resistance of internal masonry walls.
A new species of the genus Notaris Gernar, 1817 (Coleoptera: Curculionidae) from Kazakhstan
Authors: Legalov Andrei A.
Published: December 2021

A new species, Notaris (Asionotaris) temreshevi Legalov, sp. nov. from Trans-Ili Alatau (Kazakhstan) is described and illustrated. The new species is similar to N. (A.) imprudens Faust, 1885 from Kyrgyzstan but differs from it in the smaller body sizes, the pronotum punctate by large points, densely punctate elytral interstriae with long setae, and the apex of the aedeagus weakly extended forward. A distribution map for N. (A.) temreshevi Legalov, sp. nov. and N. (A.) imprudens is given.
Features of the infocommunication infrastructure development management mecha-nism
Authors: Kolotov Yuriy O. , Yablochnikova Irina O.
Published: December 2021

In the context of the Industrial Revolution 4.0 and the total digitalization of socio-economic processes in society, research related to the development and justification of effective mechanisms for managing the innovative development of modern infocommunication infrastructure and ensuring a high level of efficiency of the practical application of infocommunication technologies (ICT) is relevant. The most important feature of the evolution of such infrastructure and the ICTs themselves is their significant correlation with the totality of processes carried out in the global and national economies. In fact, ICTs play the role of a catalyst for the above-mentioned global and local processes, predetermine the pace of scientific and technological progress. An analysis of the achievements of a number of economically developed countries over the past few decades indicates that the state of a single national economy and the dynamics of its processes directly depend on the pace of introduction of modern means of communication and telecommunications, computer networks, data centers and other innovations into all spheres.
In connection with the above, a number of global problems and local tasks arise regarding not only the adequate determination of the necessary level of development of the infocommunication infrastructure, due to the formation of new socio-economic realities, and forecasting the likely consequences of intensive use of ICT tools in various fields of activity, but also the formation of mechanisms for managing innovative development. These mechanisms should be effective and efficient in achieving the relevant management objectives.
The article pays attention to a number of aspects and features of the mechanism proposed by the authors for managing the development of the infocommunication infrastructure for the formation of the digital economy and the information society as a whole. This mechanism is based on the practical application of specific methodological tools that allow monitoring the status and potential of the infocommunication infrastructure through a comprehensive assessment of the effectiveness of the introduction of ICT. The mechanism developed by the authors for managing the development of the infocommunication infrastructure will allow public authorities to specify the strategy and tactics of forming the foundations of the digital economy and the information society as a whole.
The relationship between logistics and trade marketing in FMCG companies
Authors: Kegenbekov Zhandos K. , Alipova Alima N. Alipova , Bidasheva Alina G. Bidasheva
Published: December 2021

Logistics and marketing are usually concerned with satisfying the needs and wants of customers, respectively through their supply and demand functions in the marketplace.  In order for organizations to successfully provide more value to customers, it is necessary to combine logistics and marketing functions. Globally, the importance of transport in every nation's economy is increasing every year, as its level of development has a major impact on the competitiveness of a nation's economy. The relevance of the study is that the relationship between logistics and marketing is crucial to serve FMCG market customers. A successful relationship between logistics and marketing, represents a source of competitive advantage to provide better customer service while keeping the cost of goods low. This paper presents the theoretical basis for the logistics organization of Kazakhstan's FMCG market. The current situation of domestic FMCG trade is presented and the contribution to the country's GDP is described. The main aspects and functions of logistics and marketing for finding joint areas and conflicts are also given. The principles of market supply chain management are described, the integration of logistics and marketing is analyzed using the concepts of trade marketing in distribution systems of modern companies as an example, and the logistics approach to trade and marketing activities is described. An important outcome of the analysis is the definition of marketing logistics as a source of competitive advantage, together with a description of digital marketing logistics technologies and the risks of their application.
La Gestión Estratégica, el Branding y su Influencia en el Marketing: ¿una asignatura pendiente?
Authors: Figueroa-Casillas Sara J. , Rosario-Ruiz María D.
Published: December 2021

Gestionar estratégicamente las decisiones de marketing corresponde a uno de los temas más importantes en el aspecto organizacional junto con el branding y el vínculo con los clientes. Sin embargo, el tratamiento individual de cada uno requiere concertar una integración de estos conceptos. Es así que se plantea un análisis de la cobertura que la literatura académica proporciona a las temáticas anteriormente mencionadas para propiciar una investigación de contenido, en donde se resalte lo importante de profundizar hacia un enfoque más integrador en estos aspectos. Para estos fines se propone un estudio reflexivo que vincule estas temáticas teniendo por hallazgo que en la práctica los académicos discutan, analicen y trabajen en campo con las áreas de negocio, esto con la finalidad de plasmar herramientas prácticas y claras para consolidar el apartado estratégico y de marketing en las organizaciones.
Progressive Supranuclear Palsy Following as Major Depressive Disorder: A Case Report
Authors: ERDAŞ Mehmed Burak
Published: December 2021

Progressive Supranuclear Palsy (PSP) is a rare neurodegenerative disease that is classified among Parkinson plus syndromes, manifesting itself with behavioral, cognitive and emotional symptoms as well as parkinsonian symptoms such as postural instability, ophthalmoplegia, bradykinesia, rigidity affecting the brain stem, basal ganglia and cerebellum. Although there is sufficient information about the pathological process and clinical presentation of PSP, there is no valid biomarker for diagnosis, clinical findings and neuroimaging are very important in diagnosis, patients often get misdiagnosis at their first application. It has been reported that psychiatric symptoms are common in these individuals due to the involvement of the frontal-subcortical circuits, and therefore patients can get psychiatric diagnoses in the early period. We aimed to present a 72-year-old female patient who was followed up with the diagnosis of major depressive disorder in various centers for about 4 years, who did not benefit from psychiatric treatment, and diagnosed with PSP eventually. We also aimed to emphasize that importance of considering neurodegenerative diseases in differential diagnosis in patients whose depressive symptoms begin at an advanced age, are resistant to treatment and have atypical symptoms such as the presence of accompanying neurological findings, and psychiatric symptoms may be the first symptom of neurodegenerative diseases.
Opinions of Medical Faculty Students about Anatomy Practical Education: A Survey Study
Authors: ATEŞOĞLU KARABAŞ Sibel , DEMİR Mehmet , YOLDAŞ Atila , ÇİÇEK Mustafa
Published: December 2021

Aim: In our study, it was aimed to evaluate the opinions of students studying at Kahramanmaras Sutcu Imam University Faculty of Medicine about the current state of anatomy practical education. Material and Method: A total of 64 students, 36 men and 28 women, were included in the study. In this cross-sectional, descriptive type study, students’ views on anatomy education were determined using a voluntary survey method. In the content of the survey, there were questions that questioned the demographic characteristics of the students, their thoughts about the practical education of anatomy they received, and questions that determined their ideas about the provision of models. In the answer to other questions, a likert-type scale of 5 was used consisting of the options “always”, “mostly”, “often”, “occasionally”, “never”. The data was analyzed with IBM SPSS Statistics 25.0 package program. Results: The average age of 64 students participating in the study was 20.98± 1.10. Of these students, 33(51.6%) were in semester II and 31(48.4%) were in semester III. Students reported that the practical training in anatomy they received was moderate, that the model and cadaver should be used together in lessons, that training on the model was very effective in learning anatomy. In the results, it was observed that the variety of models available in our laboratory was sufficient, but due to the presence of classes, the number of models was not sufficient, it would be better to drop one model for every 1-5 people on the average. Conclusion: Students were moderately satisfied with the learning practices within the scope of the anatomy practical course. With the support of Kahramanmaraş Sütçü İmam University Research Projects Coordination Unit (Project no:2020/3-28A), thanks to the newly provided models, the reinforce laboratory allows students to better understand the lesson and learn the subjects they are having difficulty with.
Gossypin Suppresses Cell Growth by Cytotoxic Effect and Induces Apoptosis in MCF-7 Cells
Authors: ÇİÇEK Mustafa , ÇINAR İrfan , AKSAK Selin
Published: December 2021

Aim: Today, breast cancer is a disease that is encountered commonly in women with limited options for treatment. It is needed to find new agents that can be effective in preventing or managing this disease. It has been demonstrated that gossypin inhibits tumor growth. In our study, it has been targeted to examine the effects of gossypin regarding both anticancer activity and apoptosis in MCF-7 cells. Material and Method: MCF-7 cells were treated with different doses of gossypin and with 50 µM cisplatin for 24, 48, and 72 hours. The MTT analysis, Caspase-3, Caspase-9, and Nf-KB mRNA expressions of those MCF-7 cells which were treated with gossypin were also conducted in order to evaluate the apoptosis or necroptosis-induced cell death. Results: In MTT experiments, it has been observed that the administration of 100 µM dose of gossypin had similar effects to the routine cisplatin administration, caused a significant decrease in cell proliferation, and increased apoptosis in the evaluations of Hoechst staining and morphology. It has been put forth that gossypin decreases the expression of CASP-3 and CASP-9 mRNA and increases the expression of NF-kB.Conclusion: Our results demonstrate that for the breast cancer cells, the 100 µM of gossypin positively affects cell death pathways due to apoptosis.
VS Naipaul’s The Mimic Men; Degeneration of Values
Authors: YILDIZ Firat
Published: December 2021

Colonization has been an exploitative trend that has dominated some parts of the world for several centuries. It is common for the colonizer state to impose economic and political pressure on the colonized state, as well as pressure on the religion, language, and culture of that society in question. V. S. Naipaul is a Trinidadian writer whose country has been colonized for centuries. In this framework, his works frequently mirror the colonial and postcolonial periods. The Mimic Men is an important work in terms of witnessing both the colonial and postcolonial periods. The semi-autobiographical life of Ralph Singh, the protagonist of the story, takes place in the fictional island of Isabella. With Singh's grandparents being indentured servants who migrated to Isabella from India and the island being in the Caribbean, it has a lot in common with Naipaul's actual life. As a result of living detached from their traditional values, societies that have been colonized for a long time have had their religion, language, and culture distorted, as well as failing to build a healthy character. This study aims to focus on the value corruption caused by the colonial process in the novel.
ПЕРВЫЕ УТОПИЧЕСКИЕ СНЫ В ТУРЕЦКОЙ И РУССКОЙ ЛИТЕРАТУРАХ
Authors: GÜRSOY Yasemin
Published: December 2021

Цель исследования — сравнительный анализ первых утопических снов в турецкой и русской литературах. Предметами исследования являются повести «Сон “Счастливое общество”» Александра Петровича Сумарокова и «Сон» Намыка Кемаля. Актуальность выбора темы обусловлена, во-первых, тем, что сравнительный анализ турецкой и русской утопий малоизучен. Во-вторых, тема показывает, что сны в жанре утопии используются в качестве мотива в разных эпохах и культурах. В статье кратко рассказывается о появлении жанра утопии в турецкой и русской литературах. Анализируются социальные и культурные различия через утопические сны двух авторов. В работе предпринимается попытка передать черты, которые русские и турецкие писатели ищут в идеальном обществе, с помощью цитат из произведений А. Сумарокова и Н. Кемаля. В результате доказано, что тема поиска идеальной формы государства и жанр утопии используются в литературе разных обществ и периодов, и утопические сны — идеальный способ для этого жанра.
The impact of advanced technology on the corporate economy
Authors: Dementev Dmitriy
Published: December 2021

The article examines the evolution of advanced technologies and its impact on the development of the economy. The processes of mutual influence of advanced industrial technologies and trends in the formation of technological structures attract the attention of economists, engineers, and sociologists. A human being is constantly trying to conceive the algorithms for assessing mutual influence of advanced technologies on technological progress, on global and national economies. Scientific discussion will lead to valuable practical results if scientists speak «the same language», use a unified interpretation of technical, economic, statistical, social terms. It is crucial to place social aspects of technological progress in the forefront since technological development is to solve the problem of the most technological or economical satisfaction of human needs. The purpose of this work is to investigate the existence of mutual relationship between the use of intellectual property and the economic development of Russia’s manufacturing industries. The methodology is based on the principles of the consistency of scientific research, objectivity, causation of phenomena in the economy. The paper applies the methods of economic and statistical analysis and presents a brief overview of scientific publications on the impact of advanced technologies on economic development for the period of 2018-2020. The author puts forward a hypothesis that an empirical analysis of advanced technologies in the production of electronic products will show the degree of patents influence on industry productivity. The findings demonstrate that technologies have a weak influence on productivity both on the economy at large and in manufacturing industry. Therefore, patenting the technologies should be scientifically substantiated and it is imperative to confirm the promise of advanced technologies for sustainable development.
Carbon price: theory and practice of greenhouse gas emissions regulation
Authors: Stepanov Ilya , Galimova Karina
Published: December 2021

In the context of transition to low-carbon development, carbon price is rapidly gaining ground all over the world. Discussions on its implementation are under way in Russia as well. However, the use of carbon price as an indicator can be compounded by certain risks. In practice, to overcome them depends on the ability of carbon price designing to take into account the specifics of a country or industries where the regulation is introduced. The regulator needs to determine the specifics of carbon pricing, identify the acceptable degree of regulation and coverage of carbon price; consider the consequences for vulnerable sectors of population, companies, etc. The study aims at systematizing theory and practice of carbon pricing across various countries and regions of the world economy. Drawing on the analysis of fundamental
and empirical works, the authors identify the factors that limit the effective use of carbon price; classify the key elements of carbon pricing design. Based on the analysis of international experience, the article provides recommendations on the development of a system for regulating carbon in Russia.
Automotive industry ecologization: advantages and challenges of alternative fuel vehicles implication
Authors: Akimova Olga , Volkov Sergey , Kuzlaeva Irina
Published: December 2021

The article is dedicated to the problem of identifying strategic groups in the business education market. The authors conducted a systematic review of publications on the topic. The object of the research is the developed markets of business education in the USA and Western Europe, the subject of the research is the groups of relatively homogeneous educational institutions that demonstrate similar strategic behaviour (strategic groups). For researchers, dividing market participants into strategic groups is the basis for identifying efficiency factors in the respective groups, and for heads of educational institutions and market regulators, it is a prerequisite for constructing meaningfully interpreted rankings and business school ratings. The purpose of the work is to identify trends in changes of the business-schools grouping approaches and the factors underlying such groupings. The authors revealed a shift of researchers' the emphasis from the characteristics of educational programs offered by schools to the positioning of schools in a wide social and educational environment. Although the strategic analysis level is growing, the discussion topic remains fragmented and covers only a part of the business education markets.
Manejo de arvenses
Authors: Salazar-Gutiérrez Luis , Torres Fabio Alexis
Published: December 2021

El Manejo Integrado de Arvenses (MIA) se basa en entender la importancia de la cobertura del suelo para prevenir su erosión. Durante los primeros 2 años de edad del cultivo, el café es muy sensible a la competencia de las arvenses (plantas acompañantes de los cultivos), y el suelo se encuentra más propenso a la erosión por efecto de las lluvias. Igualmente, durante la etapa productiva las arvenses más agresivas compiten fuertemente por el agua y los nutrientes del suelo, llegando a reducir la producción en más del 60%.
Chasing the Tail of Cosmic Reionization with Dark Gap Statistics in the Lyα Forest over 5 < z < 6
Authors: Zhu Yongda , Becker George D. , Bosman Sarah E. I. , Keating Laura C. , Christenson Holly M. , Bañados Eduardo , Bian Fuyan , Davies Frederick B. , D’Odorico Valentina , Eilers Anna-Christina , Fan Xiaohui , Haehnelt Martin G. , Kulkarni Girish , Pallottini Andrea , Qin Yuxiang , Wang Feige , Yang Jinyi
Published: December 2021

We present a new investigation of the intergalactic medium (IGM) near the end of reionization using “dark gaps” in the Lyα forest. Using spectra of 55 QSOs at z
em > 5.5, including new data from the XQR-30 VLT Large Programme, we identify gaps in the Lyα forest where the transmission averaged over 1 comoving h
−1 Mpc bins falls below 5%. Nine ultralong (L > 80 h
−1 Mpc) dark gaps are identified at z < 6. In addition, we quantify the fraction of QSO spectra exhibiting gaps longer than 30 h
−1 Mpc, F
30, as a function of redshift. We measure F
30 ≃ 0.9, 0.6, and 0.15 at z = 6.0, 5.8, and 5.6, respectively, with the last of these long dark gaps persisting down to z ≃5.3. Comparing our results with predictions from hydrodynamical simulations, we find that the data are consistent with models wherein reionization extends significantly below redshift six. Models wherein the IGM is essentially fully reionized that retain large-scale fluctuations in the ionizing UV background at z ≲6 are also potentially consistent with the data. Overall, our results suggest that signatures of reionization in the form of islands of neutral hydrogen and/or large-scale fluctuations in the ionizing background remain present in the IGM until at least z ≃ 5.3.
r-Process Radioisotopes from Near-Earth Supernovae and Kilonovae
Authors: Wang (王夕露) Xilu , Clark Adam M. , Ellis John , Ertel Adrienne F. , Fields Brian D. , Fry Brian J. , Liu Zhenghai , Miller Jesse A. , Surman Rebecca
Published: December 2021

The astrophysical sites where r-process elements are synthesized remain mysterious: it is clear that neutron star mergers (kilonovae (KNe)) contribute, and some classes of core-collapse supernovae (SNe) are also possible sources of at least the lighter r-process species. The discovery of 60Fe on the Earth and Moon implies that one or more astrophysical explosions have occurred near the Earth within the last few million years, probably SNe. Intriguingly, 244Pu has now been detected, mostly overlapping with 60Fe pulses. However, the 244Pu flux may extend to before 12 Myr ago, pointing to a different origin. Motivated by these observations and difficulties for r-process nucleosynthesis in SN models, we propose that ejecta from a KN enriched the giant molecular cloud that gave rise to the Local Bubble, where the Sun resides. Accelerator mass spectrometry (AMS) measurements of 244Pu and searches for other live isotopes could probe the origins of the r-process and the history of the solar neighborhood, including triggers for mass extinctions, e.g., that at the end of the Devonian epoch, motivating the calculations of the abundances of live r-process radioisotopes produced in SNe and KNe that we present here. Given the presence of 244Pu, other r-process species such as 93Zr, 107Pd, 129I, 135Cs, 182Hf, 236U, 237Np, and 247Cm should be present. Their abundances and well-resolved time histories could distinguish between the SN and KN scenarios, and we discuss prospects for their detection in deep-ocean deposits and the lunar regolith. We show that AMS 129I measurements in Fe–Mn crusts already constrain a possible nearby KN scenario.