bluuebunny/crossref_metadata_2025 huggingface dataset:
Full-thickness corneal suture analysis using anterior segment Ocular Coherence Tomography (AS-OCT)
Authors: Pérez Sara Margarita Pérez , Arias Valentina Cárdenas , Pino Margarita María Perilla , Martínez Camilo Eduardo
Published: December 2022

Purpose: To evaluate the anatomic and visual outcomes of patients who underwent full-thickness corneal suture in penetrating ocular trauma.
Methods: A retrospective observational study was conducted after analyzing the medical records of 7 patients who presented to the ohptalmology department of the Hospital Universitario San Ignacio, during January 2020 and December 2021, with diagnosis of penetrating ocular trauma requiring corneal suture with subsequent anterior segment ocular tomography (AS- OCT) at 2 weeks post-trauma.
Results: In 2 of the 7 patients included in the cohort intraocular foreign body was found. The average age at presentation of the trauma was 47 years, with a higher rate (71.4%) in men. The average time between trauma and surgery was approximately 2.6 days. In 100% of the patients the corneal architecture was restored, defined by the adequate apposition of the corneal endothelium between both sides of the wound.
Conclusions: The present study provides promising results regarding the use of full-thickness corneal suture in the context of penetrating ocular trauma. This intervention, employed at the 100% of the patients studied, adequately restores corneal architecture, positively impacting postoperative visual acuity.
Analysis of long term spatio- temporal trend of rainfall in Tamil Nadu between 1981-2020
Authors: Sembanan Kokilavani , Subbiah Ramanathan , Vellingiri Geethalakshmi , Ganesan Dheebakaran , Nakaranai Sathyamoorthy , Shanmugam Mohankumar
Published: December 2022

Increased anthropogenic activity in recent decades has resulted in major global climate change. This paper mainly focuses on the assessment of changes occurring in the spatio -temporal distribution of rainfall with 40-years database of monthly precipitation for Seasonal Precipitation Concentration Index (SPCI) and trends in Tamil Nadu. The hydro-meteorological time series rainfall data over a period of 40 years (1981–2020) was collected from Tamil Nadu Agricultural University and India Meteorological Department and subsequently analysed using various statistical methods for Tamil Nadu. The SPCI was analysed for both southwest and northeast monsoon. SPCI values (< 10) revealed that the rainfall was uniformly distributed in southwest and SPCI values (> 10) showed that more weather extremes were observed during northeast monsoon. Mann–Kendall, non-parametric test was done using trend software for both the monsoon. During southwest, significant increasing trend in rainfall was observed at Coimbatore (1.8mm/season/year), Erode (2.1mm/season/year), Perambular (2.1mm/season/year), Theni(2.0mm/season/year) and Tirunelveli (2.4 mm/season/year) while significant decreasing trend in rainfall was observed at Namakkal(2.5 mm/season/year). During northeast, significant increasing trend in rainfall was observed Kancheepuram (2.4 mm/season/year), Tutucorin(2.6 mm/season/year) and Villupuram(2.0 mm/season/year).
Association of HLA-DPA1 and DQA1 genes with PLE in Han and Tibetan males in Qinghai, China
Authors: Cao FaLong , Li JunPeng , Duan ZhiLi , Luo JunMing , Liu Xia , Zhang XiaoCen , Liu XueShan , Peng Yan
Published: December 2022

BACKGROUND
Polymorphic light eruption (PLE) is the commonest photosensitive disorder, characterized by pruritus, erythematous papules, plaques or blister lesions that occur within hours of exposure to ultraviolet radiation. However, the etiology and pathogenesis of PLE are still uncertain. The current study aims to identify the relationship between HLA and PLE, and analyze the discrepancies between Han and Tibetan males on the association of HLA with PLE.
METHODS
Polymerase chain reaction sequence-based typing (PCR-SBT) method was used to determine the distribution of HLA-DPA1 and -DQA1 alleles among 62 male patients with PLE (45 Hans and 17 Tibetans) and 66 healthy males (52 Hans and 14 Tibetans) in Qinghai region.
RESULTS
4 HLA-DPA1 and 11 HLA-DQA1 genotypes were detected in all samples. The allele frequency of HLA-DPA1*01:03 in healthy Han men was significantly higher than that in healthy Tibetan men (Pc=0.008), while the HLA-DPA1*02:01 was significantly lower than that in Tibetan men (Pc=0.04). The frequency of HLA-DQA1*03:03 allele (OR=2.7891, Pc=0.011) was significantly increased in Han men with PLE compared with Han controls , and HLA-DPA1*01:03 allele (OR=7.217, Pc=0.0076) was significantly increased in Tibetan men with PLE than Tibetan controls, whereas HLA-DPA1*02:01 (OR=0.154, Pc=0.008) allele frequency was highly decreased in Tibetan men with PLE.
CONCLUSIONS
There were racial differences between Han and Tibetan men in HLA gene polymorphism. The HLA-DQA1*03:03 allele could be a susceptible allele of PLE in Han men, and the HLA-DPA1*01:03 allele could be a susceptible allele of PLE in Tibetan men, while the HLA-DPA1*02:01 allele could be a protective allele in Tibetan men.
Discovery and Identification of Candidate Genes, Diagnostic Model and Drug Predictions for Schizophrenia and Crohn's Disease Through Integrated Bioinformatics Analysis and Machine Learning
Authors: Feng Yu , Shen Jing
Published: December 2022

Background
Both schizophrenia and Crohn's disease are linked to the expression of immunological and metabolic abnormalities. The objective of this research is to find appropriate diagnostic candidate genes for patients with schizophrenia and Crohn's disease as well as the appropriate medications.
Methodology:
The datasets were retrieved from the Gene Expression Omnibus (GEO) database for schizophrenia and Crohn's disease. Differentially expressed genes (DEGs) were identified using the Limma package and weighted gene co-expression network analysis (WGCNA). The function enrichment analysis was conducted, followed by machine learning-based identification of candidate immune-related central genes for least absolute shrinkage and selection operators (LASSO) regression and construction of protein-protein interaction (PPI) network. The random forest method was used to identify candidate genes and establish artificial neural networks for the verification of these genes. And for the diagnosis of schizophrenia, the receiver operating characteristic (ROC) curve was plotted. The Enrichr database was then used to collect pertinent drugs that are related to candidate genes.
Results
A total of 2681 DEGs and 210 Crohn's disease-related genes were screened out in schizophrenia. Among the schizophrenia and Crohn's disease-related genes, about 35 genes depicted differential expression. Finally, seven potential genes were screened out using the PPI network and machine learning. The diagnostic value was evaluated using the ROC curve data. These findings suggest that the diagnostic value of these candidate genes is high. Valproic acid and other related drugs were collected from the enrichr database.
Conclusion
The identification of seven candidate gene models (CAP1, INSIG1, MSMO1, PHLDA2, PSMB6, TBC1D2, UBA5) has high diagnostic value, and valproic acid and other drugs may become candidate drugs for patients with schizophrenia, providing effective evidence for the pathogenesis and treatment.
RETRACTED: Wear Mechanism and Material Deposition of High Strength Polymers for Hydrogen Compression
Authors: WINKELMANN H. , PÖLLINGER A. , BERNARDI J. , WHITMORE K. , SCHWARZ S. , KRENN S. , SEICHTER S. , SCHOEBEL M.
Published: December 2022

The authors have requested that this preprint be removed from Research Square.
A facile approach towards Hierarchical Zeolite Y Synthesis from Inexpensive Precursor
Authors: Usman R. A. , Kovo A. S. , Abdulkareem A. S. , Garba M. U.
Published: December 2022

Microporous zeolite is one of the most utilized heterogeneous catalyst in many chemical reactions in process industries. It has a unique selectivity property, stability in high thermal reaction and porosity to enhance chemical reaction. The micropore associated with the conventional zeolites poses some constrains in reaction involving bulky reactant thereby causing deactivation of zeolite catalyst. Therefore, to overcome this constrain, a hierarchical structured zeolite catalytic material was proposed as it is known to have pores of difference dimensions which can overcome inaccessibility experienced in the smaller pore zeolites. In this work, a hierarchical zeolite Y catalyst was synthesized using a poorly crystalline inexpensive Aloji Kaolin from Nigeria as an aluminosilicate material through a facile modified Top down approach in which the zeolite Y was initially prepared from the kaolin via hydrothermal method and then followed by desilication using mild solution of sodium hydroxide. The synthesized hierarchical zeolite Y was characterized with the aid of powder X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM), Brunauer-Emmett-Teller (BET) analysis. The synthesized hierarchical Y has crystallite size of 35.67nm, surface area of 18.1114m2/g, pore size 50.676Å, and pore volume 0. 23178cm3/g.
The Interactive Effects of Extreme Temperatures and PM2.5 Pollution on Mortalities in Jiangsu Province, China
Authors: Zhou Lian , Wang Yuning , Wang Qingqing , Ding Zhen , Jin Hui , Zhang Ting , Zhu Baoli
Published: December 2022

Background Exposure to either extreme temperatures or fine particles (PM2.5) is associated with adverse health outcomes but their interactive effects remain unclear. Here, we aimed to explore the interactions of extreme air temperatures and PM2.5pollution on total and cause-specific mortalities. Methods Based on the daily mortality data collected between 2015 and 2019 in Jiangsu Province, China, we conducted generalized linear models to estimate the regional-level independent effects of cold/hot extremes and PM2.5pollution. We further evaluated the relative excess risk due to interaction (RERI) to represent the combined effects. We estimated the joint effects with different extreme temperatures and PM2.5pollution cutoffs. Results The relative risks (RRs) of total and cause-specific mortality associated with hot extremes were significantly stronger (p < 0.05) than those related to cold extremes across three regions in Jiangsu; the associations with cold extremes were less consistent. We identified significantly higher interactions (p < 0.05) between hot extremes and PM2.5pollution than those between cold extremes and PM2.5pollution, with RERIs ranging between 0.00 and 1.15 in hot seasons. The joint effects peaked on ischaemic heart disease (RERI = 1.13 [95%CI: 0.85, 1.41]) in middle Jiangsu. For respiratory mortality, RERIs were higher in females and in the less educated. The interaction pattern remained consistent when defining the extremes/pollution with different thresholds. Conclusion This study provides a comprehensive picture of the interactions between extreme temperature events and PM2.5pollution on total and cause-specific mortalities. The projected interactions call for coordinated policies and public health actions to face the twin challenges, especially the co-appearance of hot extremes and PM pollution.
SOCIAL AND POLITICAL INFLUENCE ON THE TRANSFORMATION OF THE IMAGE OF BUDDHISM IN THE MASS CONSCIOUSNESS OF THE RUSSIANS OF TRANSBAIKALIA
Authors:   Transbaikal State University, Zhukov A. , Zhukova A ,   Transbaikal State University, Romanova N ,   Transbaikal State University
Published: December 2022

The article is devoted to the topical problem of interaction between mass consciousness of Russians and Buddhism in Transbaikalia. The object of the study is the spread of Buddhism in Transbaikalia. The subject of the study is the transformation of Buddhist images in the mass consciousness of the Russian population of Transbaikalia. The aim of the study is to find patterns in the process of interaction between Buddhism and the mass consciousness of the Russians. The theoretical background of the research is provided by the conceptual positions of M. Weber's [9] and E. Durgheim's [11] theory of the social nature of religious consciousness, M. Buber's [7], V. S. Bibler's [6] and M. M. Bakhtin's [5] theory of the dialog of cultures, N. I. Konrad's [15] theory of Buddhist reception in non-Buddhist societies, and E. S. Safronova [20]. Research methodology is presented by comparative, dialectical, and complex approaches that allow tracing the stages of Buddhism transformation in the consciousness of the Russians in Transbaikalia. The following research methods have been used by the authors: typology, reconstruction, observation, description, as well as phenomenological method, allowing to conceptualize the Buddhist images in the consciousness of Russians. The authors present substantiation of socio-political influence on transformation of the image of Buddhism from "alien" to "traditional" religion. The novelty of the study presented by the authors is associated with the disclosure of the stages of the process of Buddhism images transformation in the consciousness of the Russian population of Transbaikalia. In the process of the analysis, carried out with methods of comparative, dialectical and phenomenological analysis, the authors reveal patterns of Buddhism image transformation in Russian mass consciousness. The result is the proof of the position that the transformation of the image of Buddhism in the mass consciousness of the Russian population of Transbaikalia represents a process of gradual transition from the perception of Buddhism as an "Alien" religion, embodying the inertia of the population of colonized territories, to the image of "Useful" Buryat religion, helping in difficult life situations any converted, and finally to the image of "Our" Russian religion, which is a stronghold of traditional values and culture
MANAGING HUMAN CAPITAL IN INDUSTRIAL RESTRUCTURING: THE IMPACT ON REGIONAL ECONOMIC DEVELOPMENT
Authors:   Novosibirsk State University of Economics and Management, Novosibirsk, Glotko A , Shelkovnikov S ,   Novosibirsk State Agrarian University, Novosibirsk, Kuznetsova I ,   Novosibirsk State Agrarian University, Novosibirsk
Published: December 2022

This article is devoted to the development of a set of measures to improve the management of human capital of workers of pre-retirement age in the interests of the economic development of the region with structural changes in industry. The study has been conducted on the example of the Altai Republic. The object of the study is the pension reform and its impact on the management of human capital, the subject of the study is the processes of managing the human capital of workers of pre-retirement age in the Altai Republic. Theoretical and methodological foundations for assessing the implementation of the pension reform and its impact on the management of human capital in the region with structural changes in industry have been studied. The concept of "human capital" is considered and people of pre-retirement age and pensioners are singled out in a separate category. The general criteria for assessing human capital in Russia are considered; the experience of foreign countries in terms of pension provision of the population is given. The analysis of the processes of evaluating the implementation of the pension reform and its impact on the management of human capital in the Altai Republic has been carried out. An assessment of the impact of the pension reform on the management of human capital in the region with structural changes in industry is made. It is noted that there is a constant increase in the proportion of people of pre-retirement age, the use of the human capital of these workers, which is of high quality, is an urgent topic that requires special research. Social projects are aimed at improving the quality of the human capital of older people. The aim of the study is theoretical issues and methodological recommendations for human capital management. The object of study is the processes that determine the directions and ensure the efficiency of the use of human capital. The following methods are used in the process of the study: monographic, abstract-logical, sociological, calculation-constructive. A set of measures is proposed to improve the implementation of the pension reform and its impact on human capital management in the Altai Republic, including the development of a regional employment program for people of pre-retirement age; allocation of job quotas for the employment of pensioners; improve the system of calculating pensions in connection with the new conditions for retirement, etc
INVESTMENTS IN THE INFORMATION AND COMMUNICATION INDUSTRY OF THE REPUBLIC OF KOREA AS A KEY FACTOR IN ECONOMIC GROWTH
Authors:   Financial University under the Government of the Russian Federation, Moscow, Tregub I. ,   Financial University under the Government of the Russian Federation, Moscow
Published: December 2022

The dynamics of today's South Korean economy have been studied and the key factors that have a significant impact on its growth have been identified. The object of the study is the volume of investment in the information and communication industry in the Republic of Korea. The subject of the study is the peculiarities of investment activity in the Republic of Korea in the information and communication industry and the relationship with the economic growth of the country. Thus, the purpose of the study is to investigate the existence of a causal relationship between the volume of investment in ICT and economic growth of the national economy of the Republic of Korea, considering also foreign direct investment and the number of companies in the information and communication industry in the country. One of the main challenges at this stage of economic development is to increase investment activity from internal and external actors for sustainable economic growth. Research methodology and methods. The study proposes an integral indicator of the volume of investment in ICT, GDP, foreign direct investment and the number of organizations in the ICT industry used in international research in the analysis of the growth factor of the economy of the country. Econometric models have been built to analyze the effectiveness of investment in ICT to stimulate economic growth as a whole. Based on the correlation analysis of seasonally adjusted quarterly time series for the period from 2005 to 2021, available from the Korean Statistical Information Service (KOSIS), an econometric model has been developed to determine the degree of influence of repressors on the country's GDP. It means that investments in information and communication technologies (ICT) are interconnected with the growth of the GDP of the Republic of Korea. With an increase in investment in ICT by one thousand US dollars, GDP increases by an average of 9.9 billion won (7.7 million US dollars). Is is also found out that foreign investments (FDI) in the telecommunications industry are not so effective and with their growth, GDP increases by 0.04 billion won (32 thousand US dollars). The ICT investment strategy disclosed in this study is particularly useful for policy makers planning economic growth in South Korea and other ICT-rich countries because promoting the use of ICT across all sectors requires the creation of legal and policy frameworks
The Portrait of Challenges in Teaching English to Young Learners: A Case Study in an Indonesian Islamic School
Authors: Pertiwi Canda Ayu Arum , Mustofa Mutmainnah , Ubaidillah M Faruq , Hariyanto Sugeng
Published: December 2022

Teaching English to students with no prior knowledge, a different first language, and varied characters is challenging. This research is a case study design that focused on the teachers’ perceptions of teaching English to young learners situated in one of the Islamic schools in Malang, Indonesia. The participants involved were six English teachers at the chosen school. A qualitative approach was employed in this study.  Data were generated through interviews. Findings suggest that the participating teachers encountered multiple challenges in their teaching enactment, such as (1) non-English prior knowledge, (2) lack of motivation, (3) negative perceptions of the English language, (4) time constraints for studying English, (5) insufficient teaching and learning devices, (6) messy classroom conditions, and (7) speaking anxiety. With some help from others, teachers’ creativity, and some collaborations with other teachers, the teaching and learning process can run conditionally.
When “Technology Saves Us”: Exploring and Theorizing Pandemic Pedagogies in Adult ELT Contexts
Authors: Bryan Kisha , Charles Quanisha
Published: December 2022

Educators continue to grapple with the ever-changing dynamics of COVID-19 and its effects on teaching and learning. As such, this study contributes to the limited research on the challenges and supports of English language teachers (ELTs) who work with adult learners. Much of the research on teaching during the pandemic has amplified the voices of students, K-12 teachers, and higher education faculty who teach in disciplines where courses are often already offered in online or hybrid formats. In this paper, the researchers highlight the experiences of ELTs in global settings during the onset of the pandemic, when school closure was a necessity and emergency remote teaching was seemingly the only alternative. Utilizing qualitative methodology, data was collected via questionnaires. The researchers provide a thematic analysis of teacher participants’ coping strategies, fears, hopes, challenges, and successes of what is termed ‘pandemic pedagogies for ELT’. The findings suggest that despite the ability for technology to save us, there is a need for more effective ways of responding to and caring for the English language teaching communities amid a global pandemic.
Odnos sklada interesa zaposlenika i radne okoline s radnom dobrobiti
Authors:   Fakultet hrvatskih studija, Borongajska cesta 83d, 10000 Zagreb, Černja Rajter Iva
Published: December 2022

Sklad interesa pojedinca i radne okoline (kongruentnost) temelj je profesionalnog savjetovanja. Prema Hollandovoj teoriji izbora zanimanja, kongruentnost bi trebala voditi pozitivnim profesionalnim ishodima, poput zadovoljstva na poslu, radne uspješnosti i motivacije za rad. Dosadašnja istraživanja kongruentnosti i ishoda kao rezultat dobila su vrlo niske povezanosti kongruentnosti i zadovoljstva poslom. Cilj ovog istraživanja bio je ispitati odnos kongruentnosti zaposlenika i radne dobrobiti, pri čemu je proširen raspon kriterija na nekoliko mjera radne dobrobiti: radnu angažiranost, afektivnu dobrobit, zadovoljstvo poslom i zadovoljstvo životom. Dodatan problem istraživanja bio je ispitati moderatorsku ulogu strukture interesa u odnosu kongruentnosti i radne dobrobiti. Sudionici u istraživanju bili su zaposleni građani iz raznih hrvatskih tvrtki koji rade više od 30 sati svaki tjedan (N = 526). Sklad interesa zaposlenika i njihove radne okoline računan je putem RIASEC rezultata na Upitniku profesionalnih interesa i RIASEC procjena radnih okolina. Rezultati su pokazali da je kongruentnost, kada je operacionalizirana suvremenim indeksima, nisko pozitivno povezana s energičnosti i predanosti na poslu kao subskalama radne angažiranosti te s doživljavanjem ugodnih emocija na poslu. Pri tome se mjera kongruentnosti temeljena na Euklidskoj distanci pokazala najboljom operacionalizacijom konstrukta. Mjere strukture interesa uglavnom se nisu se pokazale značajnim moderatorom odnosa kongruentnosti i radne dobrobiti. Iznimka je moderatorska uloga konzistentnosti interesa koja djeluje na način da je odnos kongruentnosti i zadovoljstva životom snažniji za pojedince koji imaju nekonzistentne profile interesa. Ključne riječi: kongruentnost interesa i radne okoline, radna dobrobit, diferenciranost i konzistentnost profesionalnih interesa, visina profila
Research on precipitation prediction based on a complete ensemble empirical mode decomposition with adaptive noise–long short-term memory coupled model
Authors: Guo Shaolei , Wen Yihao , Zhang Xianqi , Zhu Guoyu , Huang Jiafeng
Published: December 2022

Scientific precipitation predicting is of great value and guidance to regional water resources development and utilization, agricultural production, and drought and flood control. Precipitation is a nonlinear, non-smooth time series with significant stochasticity and uncertainty. In this paper, a complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) with long short-term memory (LSTM) model is developed for predicting annual precipitation in Zhengzhou city, China, which is compared with a single LSTM model, an ensemble empirical mode decomposition–LSTM model, a complementary ensemble empirical mode decomposition–LSTM model, and a CEEMDAN–autoregressive integrated moving average and a CEEMDAN–recurrent neural network model. The results show that the mean absolute percentage error, root mean square error, and coefficient of determination of the coupled CEEMDAN–LSTM model are 2.69%, 17.37 mm, and 0.9863, respectively. The prediction accuracy is significantly higher than that of the other five models, indicating that the proposed model has high prediction accuracy and can be used for annual precipitation forecasting in Zhengzhou city.
Poaceae Chloroplast Genome Sequencing: Great Leap Forward in Recent Ten Years
Authors: Li Jianhua , Hu Yiyu , Sun Yanqing , Zhu Qian-Hao , Fan Longjiang
Published: December 2022

The first complete chloroplast genome of rice (Oryza sativa) was published in 1989, ushering in a new era of studies of chloroplast genomics in Poaceae. Progresses in Next-Generation Sequencing (NGS) and Third-Generation Sequencing (TGS) technologiesand in the development of genome assembly software, have significantly advanced chloroplast genomics research. Poaceae is one of the most targeted families in chloroplast genome research because of its agricultural, ecological, and economic importance. Over the last 30 years, 2,050 complete chloroplast genome sequences from 40 tribes and 282 genera have been generated, most (97%) of them in the recent ten years. The wealth of data provides the groundwork for studies on species evolution, phylogeny, genetic transformation, and other aspects of Poaceae chloroplast genomes. As a result, we have gained a deeper understanding of the properties of Poaceae chloroplast genomes. Here, we summarize the achievements of the studies of the Poaceae chloroplast genomes and envision the challenges for moving the area ahead.
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option
for Alzheimer’s Disease
Authors: Yamali Cem , Donmez Seyda
Published: December 2022

Alzheimer's disease (AD) is a multifactorial, irreversible, and age-related neurodegenerative disorder among the elderly. AD attracts attention due to its complex pathogenesis, morbidity and mortality rates, and the limitations of drugs used in the treatment of AD. Cholinesterase inhibitors and N-methyl-D-aspartate (NMDA) receptor antagonists are used in the clinic. While tacrine, donepezil, galantamine, and rivastigmine are cholinesterase inhibitors, memantine is a non-competitive NMDA receptor antagonist. However, these drugs could not delay the progress of AD. The traditional clinical approach, the one drug-one target concept, is not entirely effective in the treatment of AD. Also, it is urgent to develop potent and novel anti-AD drugs by the design concept of multi-target directed ligands (MTDLs) which combine pharmacophores interacting with different pathways in AD. This article provides an overview of the noteworthy structural modifications made to tacrine to develop novel candidates for anti-Alzheimer drugs. Due to the complex pathology of AD, multi-functional tacrine-based ligands targeting different hallmarks, β-amyloid, tau protein, N-methyl-D-aspartate receptor, cholinesterases, monoamine oxidases, secretases, have been studied. Here, tacrine-based derivatives including heterocyclic structures such as dihydroxypyridine, chromene, coumarin, pyrazole, triazole, tetrahydroquinolone, dipicolylamine, arylisoxazole were reported with promising anti-AD effects compared to tacrine. In vitro and in vivo assays showed that new tacrine-based hybrids, which are selective, neuroprotective, and non-hepatotoxic, might be considered as remarkable anti-AD drug candidates for further clinical studies.
Bantuan Teknis Pembuatan Kolam Ikan Untuk Budidaya Aquaponik Di Desa Jenggala Kabupaten Lombok Utara
Authors: Sumiadi Sumiadi , Wahyuni Sri , Sisinggih Dian
Published: December 2022

Yayasan Fikri Cendekia Insani yang berlokasi di Desa Jenggala, Kecamatan Tanjung, Kabupaten Lombok Utara bergerak di bidang sosial, pedidikan dan keagamaan. Di bidang Pendidikan, Yayasan Fikri Cendekia Insani mendirikan Pendidikan Anak Usia Dini (PAUD) yang menampung anak-anak di sekitar yayasan berusia 3 sampai 6 tahun. Sedangkan di bidang keagamaan, Yayasan mengadakan kegiatan kajian keagamaan secara rutin tiap pekan dengan memanfaatkan Masjid Nurul Islam.  Untuk menambah asupan gizi berupa ikan air tawar dan sayur yang berkualitas ke murid-murid PAUD di Yayasan Fikri Cendekia Insani sekaligus memperkenalkan teknik budidaya ikan dan sayur sekaligus maka perlu dilakukan kegiatan Bantuan Teknis Pembuatan Kolam Ikan dan Instalasinya Untuk Budidaya Aquaponik di lokasi yayasan.
Studi Evaluasi Kelayakan Pengembangan Listrik Mikrohidro/PLTMH dan Surya/SHS Untuk Ketahanan Energi Listrik Desa
Authors: Utomo Teguh , Shidiq Mahfudz , Hasanah Rini Nur
Published: December 2022

Studi Kelayakan Pengembangan adalah studi yang perlu dilakukan oleh stake holder energi terbarukan untuk menentukan kelayakan POC (Point of Conection) Pembangkit Listrik Energi Terbarukan untuk dikembangkan ke Sistem Distribusi PLN setempat berdasarkan standarisasi peralatannya, baik pada bangunan sispil, mekanikal dan elektrikal. Studi ini untuk mengidentifikasi dampak negative usulan penyambungan energi listrik mikrohidro/PLTMH maupun SHS/PLTS terhadap Sistem Distribusi PLN setempat dan melakukannya langkah langkah  pencegahan terhadap dampak yang merugikan tersebut. Sebagai wilayah studi telah dipilih desa Andungbiru, kecamatan Tiris, Kabupaten Probolinggo Jawa Timur mengingat sejak tahun 2010  desa ini merupakan salah satu dari 12 desa/wilayah binaan Fakultas Teknik Universitas Brawijaya. Permasalahannya adalah pembangkit-pembangkit yang ada saat ini tidak tertangani/ terkelola dengan baik oleh karena bekerja secara sendiri-sendiri (off grid), beroperasi secara terbatas serta kurang memenuhi persyaratan teknis pembangkitan listrik yang ditandai dengan rugi daya dan jatuh tegangan saluran yang tinggi serta peralatan yang tidak memenuhi standarisasi PLN. Hal ini jauh dari harapan para stake holder oleh karena pengusahaan dan pengelolaan energi harus dilakukan secara professional, rugi daya saluran rendah serta tidak terjadi drop tegangan yang cukup tinggi pada ujung beban. Karenanya, tujuan khusus yang ingin dicapai dari riset desa ini dan urgensinya adalah (1). Mengembangkan potensi dan pemanfaatan SDE dari air/PLTMH dan surya/SHS di desa lokasi penelitian agar terkelola dengan baik dan menjadi alternatif sumber energi listrik utama bagi semua warga yang memerlukannya (2). Meningkatkan infrastuktur pendukung energi listrik berdasarkan studi evaluasi/kajian kelayakan sehingga pengusahaan dan pengelolaan energi listrik PLTMH dan SHS dapat dilakukan secara professional, memenuhi persyaratan teknis pembangkitan baik dalam kondisi on grid maupun off grid serta (3). DepartemenTeknik Elektro Fakultas Teknik Universitas Brawijaya (DTE FT UB) telah melaksanakan kegiatan MBKM dan    juga CDP bagi mahasiswa sehingga dengan keterlibatan JTE diharapkan menghasilkan draft penelitian/skripsi mahasiswa yang terlibat, keterlibatan mahasiswa dalam riset juga terganjar/ternilai pada kesetaraan mata kuliah yang diambil dan mahasiswa berperan aktif dalam  penyelesaian persoalan energi listrik di desa Andungbiru.
Enhanced Single Image Dehazing Technique based on HSV Color Space
Authors: Othman Mohammed Khalid , Abdulla Alan Anwer
Published: December 2022

The clarity of images degrades significantly due to the impact of weather conditions such as fog and haze. Persistent particles scatter light, attenuating reflected light from the scene, and the dispersed atmospheric light will mix with the light received by the camera affecting image contrast in both outdoor and indoor images. Conventionally, the atmospheric scattering model (ATSM) is a model often used to recover hazy images. In ATSM, two unknown factors/parameters must be estimated: Airlight and scene transmission. The accuracy of these estimations has a significant influence on the dehazed image quality. This paper focuses on the first parameter. It introduces a new technique for estimating the airlight based on the HSV color space. The HSV color space is utilized to identify the haziest opaque area in the image. Consequently, the amount of airlight in the selected area is calculated. To assess the effectiveness of the suggested approach, the well-known dataset, RESIDE SOTS, has been used that contains two parts; namely, SOTS-indoor and SOTS-outdoor. Each of dataset includes 500 images. Experimental findings show that the suggested approach outperforms the existing techniques in terms of peak signal-to-noise-ratio and structural similarity index`.
A Web-Based Program About Sustainable Development Goals Focusing on Digital Learning, Digital Health Literacy, and Nutrition for Professional Development in Ethiopia and Rwanda: Development of a Pedagogical Method
Authors: Bälter Katarina , Javan Abraham Feben , Mutimukwe Chantal , Mugisha Reuben , Persson Osowski Christine , Bälter Olle
Published: December 2022

Background

East African countries face significant societal challenges related to sustainable development goals but have limited resources to address these problems, including a shortage of nutrition experts and health care workers, limited access to physical and digital infrastructure, and a shortage of advanced educational programs and continuing professional development.

Objective

This study aimed to develop a web-based program for sustainable development with a focus on digital learning, digital health literacy, and child nutrition, targeting government officials and decision-makers at nongovernmental organizations (NGOs) in Ethiopia and Rwanda.

Methods

A web-based program—OneLearns (Online Education for Leaders in Nutrition and Sustainability)—uses a question-based learning methodology. This is a research-based pedagogical method developed within the open learning initiative at Carnegie Mellon University, United States. Participants were recruited during the fall of 2020 from ministries of health, education, and agriculture and NGOs that have public health, nutrition, and education in their missions. The program was conducted during the spring of 2021.

Results

Of the 70 applicants, 25 (36%) were selected and remained active throughout the entire program and filled out a pre- and postassessment questionnaire. After the program, of the 25 applicants, 20 (80%, 95% CI 64%-96%) participants reported that their capacity to drive change related to the sustainable development goals as well as child nutrition in their organizations had increased to large extent or to a very large extent. Furthermore, 17 (68%, 95% CI 50%-86%) and 18 (72%, 95% CI 54%-90%) participants reported that their capacity to drive change related to digital health literacy and digital learning had increased to a large extent and to a very large extent, respectively.

Conclusions

Digital learning based on a question-based learning methodology was perceived as a useful method for increasing the capacity to drive change regarding sustainable development among government officials and decision-makers at NGOs in Ethiopia and Rwanda.
Analisis kualitas search engine sebagai media pembelajaran online di perpustakaan perguruan tinggi di Bali
Authors: Suhartika I Putu , Haryanti Ni Putu Premierita
Published: December 2022

Introduction. Previous research on the quality of search engines through a combination of three supporting theories is limited. This research which used the three theories aims to measure the quality of search engines based on user perceptions, utilization, and recall and precision values. The three supporting theories include recall and precision analysis, TAM (Technology Acceptance Model) and WebQual.

Research methods. This study used a quantitative inferential method with questionnaires, observations, and online search.

Data analysis. This study used inferential statistical data analysis techniques which used to determine the relationships among research variables.

Results and discussion. Search engine Yahoo shows the highest recall value, while Google shows the highest precision value. The two search engine are well accepted and used frequently by users. The usability quality dimension has a significant effect on the utilization of Google and Yahoo, while the interaction quality dimension has no significant effect on those two search engines. Meanwhile, the dimension of information quality has a significant effect on Yahoo, however, it has no a significant effect on Google.

Conclusion and suggestions. The two search engines are accepted by user. They used as online learning media in universities to provide ease of use and support user interaction.
Potret analisis difusi inovasi dalam publikasi artikel ilmiah di Lentera Pustaka
Authors: Fuah Siti Mas , Ganggi Roro Isyawati Permata
Published: December 2022

Introduction. The relationship between the diffusion of innovation and the scientific publication is in the process of scientific communication through media that records previous knowledge from research. The purpose of this study is to show stages of innovation adoption from the articles in one academic journal namely Lentera Pustaka.

Data Collection Methods. This study used qualitative research approach with descriptive analysis. Data collection techniques were conducted through observations, interviews, and document study. Informants were selected using a purposive sampling technique.

Data Analysis. We analysed the data by reducing, presenting, and drawing conclusions or verification.

Results and Discussion. Innovations or new ideas from articles that have been adopted and implemented, are key points. The stage of adopting innovations from scientific articles starts from the published findings, then the adopters produce new knowledge from pre-existing knowledge.

Conclusion. The stages of adoption of article innovation in Lentera Pustaka include knowledge, persuasion, decision making, implementation, and confirmation. The editorial board of Lentera Pustaka can ask eaders to participate in the survey related to the interests of proposed research topics. This research shows that articles in scientific journals can be a solution to scientific problems.
Kulwap”: a trend of health promotion during the COVID-19 pandemic, Implementation of the STIKES Buleleng Community Partnership Project
Authors: Purnamayanti Ni Kadek Diah , Aryawan Kadek Yudi , Sundayana Made
Published: December 2022

The pandemic of COVID-19 has brought the global community into a new perspective of living. Due to the social distancing protocol, face to face meetings should be avoided. This could be a barrier in implementing the previous health promotion programs which were based on group gatherings. Hence, nowadays, the online approach has become a promising strategy. The intensive use of social media platforms in Indonesia serves as a great opportunity to penetrate the public awareness of society. The initiation of “Kulwap” (Kuliah WhatsApp or lecturing by WhatsApp), which is an approach to gather a group of people in a WhatsApp Group and deliver a lecture to this group through the application is also being implemented in STIKes Buleleng Bali. The aim of this study was to assess the effectiveness of WhatsApp as a media of health promotion. It is a part of the community partnership integrated into the educational process of nursing students. During the program, there were four major topics promoted: Non-Communicable Disease (NCD), Communicable Disease, and Wellness and Child Health Issues. This program succeeded in involving 357 participants who lived in Bali. Based on the participants’ feedback, the engagement was successful due to the use of WhatsApp as the preferred social media platform (84.3%), the beneficial contents being shared during the Kulwap (65.5%), the attractiveness of media being used in the lecture (82.8%) and the way of delivery was easy to be understood (70.3%). Almost all (98.6%) of the participants expressed their willingness to rejoin the program. Therefore, the study concluded that the use of Kulwap serves is an effective and acceptable strategy to establish a health promotion initiative during the current COVID-19 pandemic.
Evaluation of Bioactive Secondary Metabolites from Ponyfish Associated Bacteria (Photobacterium leiognathi)
Authors: Thirukumar Sangeswari , Selvaraj Uthra , Rath Srichandan , Shankar Kanchana , Muthuvel Arumugam
Published: December 2022

The marine environment continues to surprise us by producing novel bioactive substances with a wide range of benefits for humans. Materials and Methods: Marine bioluminescent bacteria Photobacterium leiognathi was isolated from pony fish, Secutorruconius which was confirmed with microscopic and molecular characterization. The secondary metabolite of the isolated bacteria was extracted with dichloromethane. The chemical fingerprinting of the isolated metabolite was analyzed through TLC, FT-IR, and HPLC. The nature of the compound present in the metabolite was identified in the gas chromatography-mass spectrometry analysis (GC - MS). The isolated extract was investigated for its antibacterial property against 10 human pathogenic bacteria and also its antioxidant activity using different assays such as 1, 1-Diphenyl-2-picrylhydrazyl, Phosphomolybdenum, Metal chelating, Hydroxyl radical scavenging and hydrogen peroxide scavenging activity. Results: The Presence of functional groups including phenols, sugars, and amino acids in the extracts were identified by TLC. Totally, nine peaks were obtained for the crude extract through the FTIR spectrum range of 400 to 4000 cm-1 for the active sample. The DCM extract showed a broad spectrum of antibacterial activity against the six human bacterial pathogens. Secondary metabolites from the bioluminescent bacteria, P. leiognathi, have strong antioxidant properties. These results will be instrumental in developing novel products with biosensors and bio-imaging applications using P. leiognathi.
The mediation role of organizational culture between employee turnover intention and job satisfaction
Authors: mohammad Ahmed jawhar , Abdulrahman Bryar Sami , Qader Khowanas Saeed , Jamil Diyar Abdulmajeed , Sabah Karkhi Khalid , Gardi Bayar , Anwer Sanarya Adnan
Published: December 2022

The present research aimed to investigate the mediation role of employee turnover factors including (employee overworked, lack of feedback, lack of growth, lack of recognition, lack of reward) with job satisfaction. The current research attempted to measure five research hypotheses developed earlier in this study. For this reason, the study employed quantitative method to examine the mediation role. An online questionnaire was prepared by the researchers through developing and adapting survey from different sources. The study was able to gather 78 filled questionnaires. The findings showed that a Sobel test revealed that organizational culture strongly mediates the association between employee turnover factors (employee overworked, lack of feedback, lack of growth, lack of recognition, lack of reward) and job satisfaction in selected private businesses in Iraq's Kurdistan.
Eficacia de los OVA y valoración desde la actitud de competencias de Química, en período de pandemia
Authors: Zamarreño Ricardo , Loyola Natalia
Published: December 2022

El objetivo de este trabajo es identificar la eficacia de los objetos virtuales de aprendizaje (OVA) en la adquisición de competencias en química entre alumnos de primer año de dos universidades de Coquimbo, Chile, y evaluar el desarrollo de competencias para el empleo y la vida en sociedad. La investigación se circunscribe a una metodología cuasiexperimental de pre y post test con grupo de control. Los instrumentos utilizados cuentan con un índice de Alfa de Cronbach de 0.8 y 0.9 respectivamente. Los resultados muestran la eficacia de los OVA en apropiación de competencias, con significación estadística entre un 79 % y 100 %. En las competencias hay evidencias de articulación entre ellas, lo que deja indicios para seguir indagando la relación entre actitudes y competencias. Se concluye que los OVA, en el proceso enseñanza-aprendizaje en línea supervisado por el docente, motivan a los estudiantes a aprender y potencian las habilidades de interpretación, modelación de análisis y ejecución de procedimientos para solucionar problemas de química.
Narrativas culturales durante las clases de EFL/ESL: una perspectiva epistemológica para proyectos interculturales
Authors: Carabelli Patricia
Published: December 2022

Las culturas están presentes en todo lo que hacemos; los contactos culturales son constantes y diferentes aspectos que atañen a la cultura surgen durante las clases de inglés como lengua extranjera o segunda lengua (EFL/ESL, por sus siglas en inglés). Como las actividades y los proyectos interculturales son comunes durante estas lecciones, y cuestiones en torno a cómo percibimos la cultura emergen en los discursos que se dan en estas, se llevó a cabo una investigación de corte filosófico intentando analizar qué enfoques epistemológicos pueden ofrecer interpretaciones válidas, realistas y humanistas sobre las culturas. Como existen diferentes nociones sobre la cultura, se investigaron las que tienen cabida en democracias liberales y se hizo foco en el concepto de narrativas culturales de Seyla Benhabib (2002). Se concluyó que, si bien esta perspectiva no puede ser considerada la única válida, es apropiada para las clases de EFL/ESL, puesto que es una visión abierta que considera aspectos tanto individuales como sociales, mientras interroga visiones estereotipadas. En el artículo se proporcionan ejemplos sobre cómo un abordaje basado en narrativas culturales puede brindar soporte teórico para la realización de proyectos interculturales.
Mundo acadêmico e realidade negra entre políticas afirmativas e antropologia e/da educação
Authors: Gusmão Neusa Maria Mendes de
Published: December 2022

As políticas públicas se colocam no cenário nacional de modo a evidenciar vários momentos em que experiências de acesso e permanência no universo acadêmico para as populações negras têm assumido configurações diversas bastante debatidas desde os anos 1990. Neste texto, pretende-se apontar aspectos positivos dessas políticas, buscando, porém, refletir a respeito de práticas que, no meio acadêmico, constituem experiências complementares e/ou alternativas às posturas mais engessadas das instituições educacionais no cumprimento das políticas afirmativas, voltadas apenas ao sistema de cotas. Nesse processo, desvela-se o importante papel das políticas públicas e da antropologia na configuração de projetos educativos alternativos no interior das instituições de ensino superior (IESs), que recebem estudantes afro-brasileiros e de nacionalidades africanas e latino-americanas.