bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic diversity, yield, and fruit quality of persimmon in the tropics
Authors: Peche Pedro Maranha , Pio Rafael , Badenes María Luisa , Naval Mar , Gil-Muñoz Francisco , Bianchini Flávio Gabriel , Locatelli Guilherme , Farias Daniela da Hora
Published: October 2023

Abstract The objective of this work was to determine the genetic diversity, yield, and fruit quality of persimmon genotypes grown in the tropics, in order to select promising genetic materials. DNA extraction was performed on young leaves of 19 persimmon genotypes. For pomological characterization, 15 genotypes were selected. From each genotype, 50 fruit at the physiological maturity stage were harvested in the morning, in order to determine the following parameters: physicochemical characteristics; and the productive variables number of fruit per plant, average fruit fresh mass, average yield, and estimated average yield in two seasons. Twenty SSR markers were tested, out of which 12 were selected to evaluate genetic similarity, which allowed of the identification of distinct groups. The mean genetic diversity value found was 0.41, which is an indicative of low diversity among the analyzed persimmon genotypes. The 'Guiombo', 'Iapar 125', 'Kakimel', 'Mikado RJ', 'Rama Forte Tardio', and 'Taubaté' genotypes show a high yield. The genotypes classified as pollination-constant astringent ('Pomelo', 'Regina', 'Rubi', and 'Taubaté') and those classified as pollination-variant astringent ('Rama Forte', 'Guiombo', and 'Cereja') are potential materials for selection and genetic breeding programs due to their excellent fruit physicochemical characteristics. The investigation through molecular markers is an efficient approach to study the genetic diversity of persimmon genotypes grown in the tropics.
Photosynthetic response of citrus to Citrus tristeza virus isolates with potential for cross-protection
Authors: Contreras-Maya Rosalba , Villegas-Monter Angel , Cruz-Huerta Nicacio , Santacruz-Varela Amalio , Ortega-Arenas Laura D. , Ochoa-Martínez Daniel-Leobardo
Published: October 2023

Abstract The objective of this work was to evaluate the photosynthetic response of citrus varieties to the inoculation of isolates T30 and T3 of Citrus tristeza virus (CTV) characterized as having potential to provide cross-protection against severe CTV isolates in citrus. Citrus plants of 'Campbell' orange, 'Persian' lime, and 'Key' lime were subjected to inoculations by both isolates by patch. Noninoculated plants were used as the control. Symptom expression, photosynthetic and transpiration rates, and stomatal conductance were evaluated by IRGA. Stomatal density and size were evaluated by epidermal impressions. The CTV isolates were also evaluated and molecularly characterized by RT-PCR and Sanger sequencing. 'Campbell' orange and 'Persian' lime plants remained asymptomatic after the inoculations. The inoculation treatments with both CTV isolates did not reduce photosynthetic capacity, transpiration rate, and stomatal conductance, in comparison with the control. Stomatal density and size varied according to the citrus species. T30 and T3 do not affect the photosynthetic responses of 'Campbell' orange and 'Persian' lime; therefore, these isolates have the potential to provide cross-protection to citrus varieties against severe isolates of CTV.
University outreach during the pandemic: digital technologies to teach energy efficiency and climate protection
Authors: Souza Ruana Tomaz de , Madruga Kátia Cilene Rodrigues , Geremias Reginaldo , Knöpker Mônica
Published: October 2023

Abstract This research aimed to evaluate the implementation of a university outreach initiative involving digital technologies toward elementary and middle-school students’ awareness of the rational use of energy and climate protection conducted during the Covid-19 pandemic. Therefore, we developed a short course, taught remotely, with twenty students from ten to thirteen years old enrolled in schools from the state system of Santa Catarina in the city of Araranguá. For this course, we developed didactic materials about the following themes: a) energy sources and emissions, b) transport energy and emissions, and c) energy efficiency and climate protection. From the data collected, we could see that the approach to energy efficiency and climate protection themes can contribute to developing perceptions about reducing environmental impacts. We have also identified the importance of contextually approaching these themes, as proposed by the course, to facilitate students’ learning and their transmission of necessary knowledge to their families regarding each person’s role in environmental protection. Hence, we can conclude that university outreach is an opportunity to approximate schools from the academy in building methodologies that lead to the teaching and learning of different topics and, perhaps, the adoption of new habits, mainly in the case of environmental education. Furthermore, we concluded that digital technologies are powerful tools for implementing outreach initiatives in pandemic contexts.
Elements of reflexivity in the academic socialization of first-generation students in higher education
Authors: Caregnato Célia Elizabete , Miorando Bernardo Sfredo
Published: October 2023

Abstract This article analyzes how first-generation higher education students elaborate expectations and action possibilities based on the relation between academic environment and social background. We analyze student trajectories to interpret the presence of elements of reflexivity associated to academic socialization. Based on ten in-depth interviews conducted in 2022 with students from a traditional federal university, we sought to understand how these students organize their action schemes, making sense of the university experience from their everyday practices. In the situations and standpoints expressed in their statements, we identified instrumental, moral, and political approaches which signal meta-pragmatic reflexive procedures. We verified that the inequalities experienced by the students in their relationships with classmates and the institution lead to socialization processes permeated by shocks. Individuals’ symbolic work on some of these dislodgments reconfigures perspectives of action in coping with difficulties. Results show that students are mobilized to persist and succeed in university by distinct types of ends: instrumental, to achieve a better life; moral, to fulfil responsibilities with their families; and political, to build up social change. Their dynamics of individuation are therefore produced with the critique of the academic environment from schemes cultivated in the transit among distinct normative environments.
Elementos de reflexividade na socialização acadêmica de estudantes de primeira geração na educação superior
Authors: Caregnato Célia Elizabete , Miorando Bernardo Sfredo
Published: October 2023

Resumo O objetivo deste artigo é analisar como estudantes de primeira geração na educação superior elaboram expectativas e possibilidades de ação a partir da relação entre espaço acadêmico e origem social. Analisamos aspectos das trajetórias estudantis para interpretar a presença de elementos de reflexividade associados à socialização acadêmica. Com base em dez entrevistas em profundidade realizadas no ano de 2022 com estudantes de uma universidade federal tradicional, procuramos compreender como os estudantes organizam seus esquemas de ação, produzindo sentidos acerca da experiência universitária a partir de suas práticas cotidianas. Nas situações e nos posicionamentos expressos em seus depoimentos, identificamos enfoques instrumentais, morais e políticos que remetem a processos reflexivos metapragmáticos. Verificamos que as desigualdades experimentadas pelos estudantes na relação com os colegas e com a instituição levam a processos de socialização permeados por estranhamentos. O trabalho simbólico dos indivíduos sobre algumas dessas desacomodações reconfigura perspectivas de ação no enfrentamento das dificuldades. Os resultados mostram que os estudantes se mobilizam para permanecer e ter sucesso na universidade a partir de finalidades: instrumentais, de conquistar uma vida melhor; morais, de exercer uma responsabilidade para com suas famílias; e políticas, de compor mudanças sociais. Suas dinâmicas de individuação se fazem, assim, com a crítica ao ambiente acadêmico, a partir de esquemas cultivados no trânsito entre diferentes ambientes normativos.
Roman Britain in Colour – Roman Altars from Hadrian's Wall Reimagined
Authors: Parkin Andrew
Published: October 2023

Roman Britain in Colour is the title of an intervention in the Hadrian’s Wall Gallery of the Great North Museum: Hancock. This intervention makes use of projection mapping to interpret a series of seven Roman altars; using colour and animation to enhance the visitor experience in the gallery. This paper explores the decision to use projection mapping technology against the background of increased interest and research into the use of pigmentation on Roman sculpture. It outlines some of the benefits of projection mapping for the understanding of archaeological material in museums and discusses some potential drawbacks of the technique as an interpretative tool.
Macro-regions promising economic specializations as a key gap in Spatial Development Strategy of Russian Federation
Authors:   Kuban State Technological University, Kozyr Natalia S.
Published: October 2023

Introduction: the Spatial Development Strategy of the Russian Federation was adopted in 2019 and included the development of strategies for 12 macro-regions, which, however, did not happen. At the end of 2022, the relevance of updating the Strategy has decreased: the number of the Russian Federation regions increased under the new geopolitical conditions, and the strategic agenda focus shifted to the new economic policy of the country, considering its national interests, sovereignty, and state security. Aims: to structure and detail promising economic specializations of the subjects of the Russian Federation in the context of macroregions. Methods: comparative analysis of documents, collection and analysis of quantitative data, structural analysis. Results: the calculations of promising economic specializations of the Russian Federation subjects within each macro-region, on the one hand, demonstrate the types of economic activities as promising specializations, on the other hand, do not make it possible to understand the country’s overall strategic development vector. The main factor limiting the development of lawmaking is the approach to the choice of economic specializations based on Russian Classification of Economic Activities which lacks an appropriate detailing. Conclusions: the Spatial Development Strategy of the Russian Federation needs to be adjusted in terms of eliminating substantive and methodological inconsistencies. It is necessary to restore the approach based on the sectors of the national economy to determine the promising economic specializations of the regions. The territorial grouping of the Russian Federation subjects into macro-regions has shown the functional inconsistency of artificial integrations. Spatial development should be focused on the infrastructural improvements of the Russian regions as a part of the federal districts, considering existing national projects and state development priorities.
Methodological approach to the formation of the region’s industrial policy
Authors:   Institute of Social and Economic Researches, Ufa Federal Research Centre of the RAS, Ataeva Aysylu G. , Ataev Dmitry M. ,   Institute of Social and Economic Researches, Ufa Federal Research Centre of the RAS
Published: October 2023

Introduction: in the context of growing geopolitical tensions, increasing external threats and restrictions, there is a need to search for new tools to ensure national security, economic stability, and technological sovereignty of the Russian Federation, including through federal and regional industrial policy. At the same time, industrial policy should correlate with the general strategic goals of socio-economic development and influence the provision of intra-regional spatial balance. Aims: to propose a methodological approach to industrial policy that strikes a balance between the region’s long-term economic competitiveness and balanced spatial development. Methods: general scientific methods, formal logical and comparative legal analysis, statistical method, methods of grouping, expert evaluation, coefficient analysis. Results: the authors proposed a methodological approach to the formation of the industrial policy in the region. The approach is based on balancing the goals and objectives of region’s increasing competitiveness and the priorities of balanced spatial development. The approach considers the economic and social interests of the territory’s main stakeholders, including state authorities and local governments. The authors have developed a methodology for assessing the spatial and industrial policy of the region, based on the analysis of inter-territorial and inter-sectoral balance and spatial-structural and structural-sectoral shifts in the industry of the region. The methodology was partly tested for 54 municipal districts and 8 urban districts of the Republic of Bashkortostan, and the results showed a significant spatial and structural imbalance in the industrial development of the region and an increase in the imbalance in retrospect. Conclusions: when developing regional strategic planning documents, authorities should take into account a combination of two directions of industrial policy: ensuring competitiveness and spatial balance.
Evaluación energética de la formación de biogás obtenido de residuos sólidos urbanos del relleno sanitario mediante el modelo LandGEM
Authors: Sofan German Stiven Javier , Arrieta Torres José David , Ruíz Garcés Alejandro , Doria Oviedo Miguel Emigdio
Published: October 2023

Objetivo: Estimar la energía disponible para generar electricidad a partir de biogás de vertedero utilizando el modelo LandGEM adaptado a las condiciones locales de Montería, Colombia. Metodología: Para ello se obtiene de base de datos y estudios la información del relleno sanitario de residuos Loma Grande ubicado en la ciudad de Montería, volumen de residuos, clima y composición de residuos para el periodo 2016-2028, para aplicar el modelo LandGEM a la producción de energía de biogás. Resultados: se observó que solo para el año 2022 la cantidad de metano calculada es de 9.984.000 m3/año y con esto la energía estimada total es de 268.4968 MWh, que podría suministrar los requerimientos del relleno sanitario Loma grande. Conclusión: El estudio predice que estos modelos de evaluación se pueden utilizar para planificar la producción de energía a partir de gas de vertedero, y así, aprovechar la propiedad de terrenos improductivos que normalmente se utilizarían como vertedero y que se crearon previamente para materiales contaminantes no destructivos.
Acceso a la educación superior en Colombia: mirada normativa desde el ordenamiento jurídico nacional e internacional en tiempos de COVID-19
Authors: Hernández García Judith Josefina , Uribe Martinez Nelson Antonio , Carvajalino Borja Gabriela del Carmen
Published: October 2023

Objetivo: El presente artículo tiene como objetivo analizar los lineamientos normativos y recomendaciones expedidas por Organizaciones Internacionales que son vinculantes por bloque de constitucionalidad a Colombia y por el Ministerio de Educación Nacional para abordar los procesos de educación superior y mantener los estándares calidad educativa. Método: Se utiliza una metodología de tipo cualitativo con un alcance descriptivo- explicativo y analítico en el que se consultaron fuentes como artículos científicos y la normatividad del ordenamiento jurídico nacional e internacional que es vinculante para Colombia, en las que se identificaron categorías de análisis: educación como derecho, educación superior como acceso, calidad de la educación y Covid 19, como elementos interviniente y transformador de la educación en Colombia en tiempos de pandemia. Resultados: En los resultados se evidencia que la Organización de las Naciones Unidas, la CEPAL y el Ministerio de Educación Nacional (MEN) de Colombia han proferido recomendaciones a las Instituciones de Educación Superior para la continuidad con calidad educativa en la nueva normalidad que suscribió el aislamiento producto del Covid-19. Conclusiones: Las conclusiones dan a conocer que, si bien existen recomendaciones y lineamientos claros para la continuidad de los procesos educativos y los estándares mínimos de calidad de estos, también es evidente que la implementación de las tecnologías de la información y la comunicación en la educación presencial con acceso remoto u otra modalidad, impide a cierta población vulnerable el acceso en equidad a ese derecho fundamental constitucional a la educación.
Los estándares internacionales de protección de la violencia basada en género de las mujeres aplicados a la inteligencia artificial predictiva
Authors: Roa Avella Marcela del Pilar , Sanabria Moyano Jesús Eduardo , Peña Piñeros Andrea Catalina
Published: October 2023

El artículo describe los estándares internacionales de protección de los derechos humanos relacionados con la violencia basada en género a las mujeres, aplicado a los sistemas predictivos derivados de herramientas que utilizan inteligencia artificial, específicamente VioGén de España. Para ello, se aplica una metodología de tipo cualitativo con alcance descriptivo que utiliza métodos sintético y exploratorio de información de fuentes doctrinales e informes oficiales sobre el uso de estas herramientas, que además es verificada con métodos propios de las ciencias computacionales que explican la arquitectura de los algoritmos; para luego contrastar con las garantías internacionales de los Estados en la protección de los derechos humanos de las mujeres víctimas de la violencia de género. Obteniendo como resultado que VioGén materializa los deberes de prevención, protección, investigación, coordinación, vigilancia y recopilación de datos. Sin embargo, se identifica retos en el abordaje de algunos tipos de violencia contra la mujer y de la aplicación de esta herramienta en las obligaciones de enjuiciamiento y castigo.
Adaptación institucional de la Policía Nacional frente a los acuerdos de paz con el M-19 y las FARC, estudio comparativo
Authors: Rubio Quintero David Fernando
Published: October 2023

A lo largo de la historia política de Colombia, los diferentes gobiernos han propendido por adelantar procesos de paz con los grupos armados, reconociendo en ello la necesidad por salvaguardar los lazos hermandad, limitar la violencia en el territorio. Por ello y especialmente desde la década de los ochenta, los gobiernos indistintamente de su filiación política adelantaron diálogos y posturas de cara a la paz, avanzando en acuerdos y negociaciones que sirvieron para evidenciar dinámicas sociales e institucionales. En consecuencia, el presente artículo de investigación tiene como objetivo realizar un estudio comparado, enfocándose en la capacidad de adaptación institucional de la Policía Nacional de Colombia frente a los acuerdos de paz con las FARC y con el grupo M-19.
Parameterization of stars and determination of interstellar extinction from multicolor photometry
Authors: MALKOV O. , DLUZHNEVSKAYA O. , KILPIO E. , MURTHY J. , SAHA S. , ZHAO G. , ZHUKOV A.
Published: October 2023

We have developed a method for the determination of stellar parameters and interstellar extinction values from multicolor photometry. The application of this method to a set of stars in a small area in the sky allows us to determine an increase of interstellar extinction with distance in that direction and, consequently, to construct a 3D extinction map of the Milky Way Galaxy.
Ergenlerin Psikolojik Zihinliliklerinin Yordayıcıları Olarak Aleksitimi ve Bilinçli Farkındalık Deneyimi
Authors: UZUN Kıvanç , KARATAŞ Zeynep
Published: October 2023

Bu çalışmada, ergenlerin aleksitimi ve bilinçli farkındalık deneyimi düzeylerinin psikolojik zihinliliklerini ne derece yordandığının belirlenmesi amaçlanmıştır. Bu amaçla, değişkenler arasındaki ilişkinin belirlenmesi için ilişkisel tarama modeli kullanılmıştır. Pandemi koşullarından dolayı çalışma grubu, uygun örnekleme yöntemi ile oluşturulmuştur. Araştırmacılar tarafından hazırlanan online form, çeşitli sosyal medya platformlarında paylaşılarak, ergenlik döneminde bulunan 582 katılımcıya ulaşılmıştır. Katılımcıların yaş ortalaması 15,24’tür. Araştırmada veriler; araştırmacıların oluşturduğu demografik bilgi formu, Ergenler için Psikolojik Zihinlilik Ölçeği, Toronto Aleksitimi Ölçeği (TAÖ-20) ve Ergenler için Kapsamlı Bilinçli Farkındalık Deneyimleri Envanteri ile elde edilmiştir. Verilerin analizinde, değişkenlerin arasındaki ilişkinin saptanması için pearson korelasyon katsayısı ile hiyerarşik çoklu doğrusal regresyon analizi kullanılırken; farklılıkların tespitine ilişkin analiz için ise ilişkisiz örneklemler t-testi ve tek yönlü varyans analizi kullanılmış, farklılıkların kaynağını test etmek adına Tukey ve Hochberg’s GT2 testlerinden yararlanılmıştır. Tüm bu istatistiksel analizlerde SPSS 22.0 programı kullanılmış olup, anlamlılık düzeyi olarak ,05 alınmıştır. Araştırma sonucunda ergenlerin psikolojik zihinliliklerinin aleksitimi düzeyleri tarafından negatif, bilinçli farkındalık deneyimleri tarafından pozitif yönde anlamlı şekilde yordandığı bulgusuna ulaşılmıştır. Ayrıca ergenlerin psikolojik zihinliliklerinin cinsiyetleri, sınıf düzeyleri, akademik not ortalamaları ve algılanan sosyoekonomik düzeyleri açısından anlamlı olarak farklılaştığı; ancak aile yapılarına göre anlamlı bir farklılık göstermediği tespit edilmiştir. Çalışma bulguları ilgili alanyazın ışığında tartışılmıştır.
The Effect of 6 Weeks of Combination of Three Cone Exercise Using Ball and High-Intensity Interval Training on the Agility and Dribbling Ability of Student Futsal Athletes
Authors: Wiranata Fajar Adi , Kusuma I Dewa Made Aryananda Wijaya , Phanpheng Yanyong , Bulqini Arif , Prianto David Agus
Published: October 2023

Study purpose. Three-Cone Drill using the Ball (TCDB) High-Intensity Interval Training (HIIT) is an exercise that requires players to perform fast movements and sharp changes of direction using a ball over three cones with high intensity. This exercise is based on the application of specific training principles using the ball and the principle of overload, which aims to improve agility and dribbling skills. This study aimed to evaluate the effect of TCDB+HIIT on the agility and dribbling ability of student futsal athletes.
Materials and methods.  This study used an experimental method with a One-Group Pretest-Posttest Design. The participants in this study were student futsal athletes, totaling 14 players aged 16.6±0.7 years, with body height 170.2±3.36 cm, body mass of 59±9.11 kg, and BMI 20.4±3.25. The research instruments used were the Illinois Agility Test and the futsal dribbling test. Data analysis used the Paired Samples T-Test at a significance level of 0.05; the prerequisite test used was the Shapiro-Wilk test.
Results. Based on the results of the Paired Samples T-Test test, it was found that the sig value (2-tailed) of the speed variable was 0.001 < 0.05, with an increase of 0.99 ± 0.57. In the dribbling variable, the sig (2-tailed) value is 0.001 < 0.05, with an increase of 1.88 ± 1.722.
Conclusions. This study concludes that TCDB + HIIT exercises are effectively applied to increase futsal players’ agility and dribbling abilities.
Is this an ad? How influencers disclose paid content after a change in the law
Authors: Gil-Muñana Lidia , Sáez-Linero Carolina
Published: October 2023

As of July 2022, the Spanish government explicitly requires influencers to disclose commercial content. However, there is no standardised model for this. This study, therefore, analyses how influencers disclose paid content and whether any significant changes came into being after the law came into force. For this purpose, a content analysis was conducted on 903 Instagram publications with brand mentions from 40 Spanish influencers. The results demonstrate that posts without any disclosure tag decreased by 25.12% following the law's implementation. Within this context, there is an observed 23.04% increase in the use of adwords (ADW) within the text and a slight increase (2.08%) in the exclusive use of Instagram's integrated paid partnership label (PPL). Despite previous studies having demonstrated that PPL is the most effective means of identifying persuasive communication, it is confirmed that its usage remains in the minority (7.19%). Likewise, most ADWs are located at the end of the caption (86.86%), remaining hidden at first sight for mobile users. Furthermore, it is observed that clear identification of commercial content by influencers is rewarded with higher organic engagement.
Durusu Kumulu sahil çamı (Pinus pinaster Ait.) ağaçlandırmalarında yaş ticari kök kütlesi miktarları
Authors: ÖZTURNA Alper Gün , PEHLİVAN Servet , MAKİNECİ Ender , TOLUNAY Doğanay
Published: October 2023

Sunulan bu çalışma ile ülkemizin endüstriyel ağaçlandırmalarında kullanılan yabancı ibreli türlerden sahil çamının (Pinus pinaster Ait.) yaş ticari kök bitkisel kütlelerini tek ağaç ve meşcere düzeyinde doğrudan tahmini için kullanılabilecek denklemlerin geliştirilmesi amaçlanmıştır. Bu amaçla, İstanbul-Durusu (Terkos) kumul ağaçlandırmalarında farklı gelişim çağlarından 45 adet örnek alanda çalışılmış ve her bir örnek alandan meşcere orta ağacını temsil eden 1 adet ağaç kesilmiştir. Kesilen ağaçların kökleri sökülerek kök kütüğü ve çapı 4 cm’den büyük köklerin yaş ağırlıkları belirlenmiştir. Örnek ağaçların yaş ticari kök ağırlıkları 12,3 kg ile 214,9 kg arasında değişmektedir. Yaş ticari kök kütlesi, ağaçların dip çapları (d0), göğüs çapları (d1,3), boyları (h) ve kabuklu gövde odunu hacimleriyle (VKGO) ilişkiye getirilerek her bir değişken için 10 ayrı regresyon denklemi test edilmiştir. Denklemlerin RMSE, ortalama hata ve ortalama mutlak hata gibi değerleri de hesaplanarak başarı sıralaması yapılmış ve aralarından en başarılı sonuçlar veren denklem belirlenmiştir. Tek ağaç düzeyinde VKGO’nun bağımsız değişken olduğu tek girişli denklem doğrusal; diğer tek ağaç denklemleri ise logaritmik formdadır. Ayrıca VKGO bağımsız değişkeninin kullanıldığı tek girişli regresyon denklemi yardımıyla meşcere düzeyinde yaş ticari kök kütlesini tahmin edebilmek amacıyla da bir regresyon denklemi geliştirilmiştir. Bu denklem ise parabolik formdadır. Bu denklemin sonuçlarına göre Durusu Kumulu sahil çamı ağaçlandırmalarında birim alandaki yaş ticari kök miktarı 12,68-199,9 t/ha arasında değişmektedir.
Social Media Interactive Advertising and Purchase Intention of the UAE Customers: An Empirical Analysis
Authors: Mohammed Yousaf Mohammed Yousaf , Koo Ah Choo , Mohd Hafizuddin Mohd Hafizuddin
Published: October 2023

The advent of social media technologies, specifically the phenomenal growth of online and interactive advertising, has assisted various organizations in responding to and communicating with respective consumers at sustainable expenditures through various online channels, including social media, with immense potential and popularity levels. Limited studies have been conducted to examine the connection between consumer engagements by small and medium enterprises (SMEs) and their respective promotional performances, as consumer purchase intention would be notably affected by the ability of an enterprise to interact and share information. Therefore, the current study aims to evaluate the impacts of attitude, brand loyalty, brand image, and brand awareness on interactive advertising and engagement with consumers via social media in the United Arab Emirates (UAE) to promote SME digital lifestyle products. Accordingly, a quantitative survey was administered to evaluate 308 responses from customers of companies vending digital lifestyle products before conducting partial least square structural equation modeling (PLS-SEM) to analyze the collected data. The results demonstrated significant positive relationships between both brand loyalty and brand awareness and consumer purchase intention, respectively, whereas the relationships between attitude and brand image and consumer purchase intention were separately discovered to be insignificant.
Breast cancer associated with intraductal papilloma
Authors: Gaman Yu. I. , Apanasevich V. I. , Laguryova A. V. , Zagrutdinova O. M. , Plekhova N. G. , Argishev O. A. , Nevozhay V. I. , Kostiv Е. P.
Published: October 2023

Background. Intraductal papilloma (IDP) is not usually considered as an obligate precancerous lesion since the cases of its progression into cancer are exceedingly rare.

Aim. To analyze the impact of IDP on the risk of breast cancer in the future.

Materials and methods. This retrospective study included patients aged 22–82 years operated on for IDP (n = 304) and other benign breast tumors (n = 304) between 2014 and 2022. We checked these patients in the cancer registry of Primorsky Regional Oncology Dispensary to find out whether any of them developed any type of cancer, including breast cancer. Then we calculated the odds of developing breast cancer in both groups.

Results and conclusion. We found that paients with a history of IDP are 2.4 times more likely to develop breast cancer. The incidence of other cancer types did not differ significantly between the two groups. Our findings are consistent with the results of similar foreign studies and might indicate that IDP and breast cancer share the same etiological factor. They can also highlight specific characteristics of asymptomatic IDP.
Assessment of ERBB2 and HER2 expression in metastatic breast cancer using the nCounter® system and a 100-gene scale
Authors: Paltuev R.  M. , Volynshchikova O.  A. , Abdullaeva Sh.  R. , Aleksakhina S.  N. , Artemyeva A.  S. , Baychorov E.  A. , Bakharev S.  Yu. , Belaya Yu.  A. , Bozhok A.  A. , Vasin V.  A. , Vladimirov V.  I. , Vorontsov A.  Yu. , Gaysina E.  A. , Gofman A.  A. , Dmitriev V.  N. , Imyanitov E.  N. , Klimenko V.  V. , Komyakhov A.  V. , Konstantinova M.  M. , Kopp M. V. , Kudaybergenova A.  G. , Lalak I.  A. , Matevosyan D.  L. , Mudzhiri N.  M. , Poltareva O.  V. , Sevryukova O.  I. , Semiglazov V.  F. , Semiglazova T.  Yu. , Urezkova M.  M. , Chichkanova A.  S. , Churilova L.  A. , Shomova M.  V.
Published: October 2023

Background. Individual molecular characteristics of a tumor can serve as a basis for a tailored approach to therapy, prediction of the disease course and outcome, and timely treatment correction in cancer patients. Tumor genomic profiling allows for a more precise tumor assessment in an individual manner. Accurate identification of the HER2 status of a breast tumor is crucial for clinical decisions and appropriate treatment strategy.

Aim. To increase the efficacy of systemic therapy for breast cancer, reduce inappropriate prescribing, and ensure a tailored approach to systemic breast cancer therapy using the information on individual molecular characteristics of the tumor.

Materials and methods. We explored the expression of 100 genes involved in breast cancer development in 106 tumor samples from patients with metastatic breast cancer. We used the nCounter technology based on direct digital target detection using color-coded molecular barcodes. We analyzed the expression of 28 genes with a high predictive value for breast cancer.

Results. The nCounter technology allowed us to perform semiquantitative assessment of the expression of 28 genes in tumor tissue samples. We compared the expression of ERBB2 and HER2. The HER2 expression between 252.32 and 6000 barcodes was equivalent to HER2 (0) status; between 6000 and 9196.25 barcodes, to HER2 (1+); between 9196.25 and 15022.46, to HER2 (2+/ISH±); and 15022.46 barcodes, to HER2 (3+). In case of HER2 (3+) and ERBB2 below 6000 barcodes, the result was considered false positive. In case of HER2 (0) or (1+) and ERBB2 above 15 000 barcodes, the result was considered false negative. In 18 tumors, the discrepancies in the results meant two principally different breast cancer subtypes requiring different treatments; in 2 cases, the discrepancies were in the level of HER2 expression.

Conclusion. HER2 testing should be performed on an excision sample (ideally on the same block that was used for genomic testing). Despite the correlation between the HER2-enriched molecular class and the response to anti-HER2 therapy, the final result on HER2 status in discordant cases should be based on currently approved assays after results validation.
Combination of pregnancy and breast cancer
Authors: Chernyshova A. L. , Chernyakov A. A. , Garbukov E. Yu. , Tarabanovskaya N. A. , Trushchuk Yu. M. , Dil O. S. , Krasilnikov S. E. , Shumeykina A. V.
Published: October 2023

Breast cancer (BC) occupies the second place in terms of incidence and the first ranking place in terms of mortality among oncopathology in women. The article presents the current state of the problem of the combination of BC and pregnancy, the impact of pregnancy on the course and outcome of breast oncopathology, as well as modern hypotheses for the development of breast cancer during pregnancy. It is shown that the current studies are quite contradictory and in many ways not accurate enough in methodology and materials. We present a clinical case of BC associated with pregnancy. The case is interesting from 2 positions: on the one hand, the patient’s tumor process is associated with pregnancy, on the other hand, there is a very rare combination of HER2/neu- and BRCA1-positive status.

According to the presented literature data and our own data, it was concluded that the treatment of patients with BC during pregnancy is a difficult task and is often accompanied by tumor progression, despite the standard treatment regimens. Undoubtedly, this group of patients needs to develop new methodological approaches to antitumor treatment based on a deep analysis of the molecular genetic characteristics of the tumor, the hormonal background in general, and its effect on the tumor process during pregnancy. Such a personalized approach will improve the results of treatment of young patients with BC during pregnancy.
Earthquakes Parameters from Citizen Testimonies: A Retrospective Analysis of EMSC Database
Authors: Vannucci Gianfranco , Gasperini Paolo , Gulia Laura , Lolli Barbara
Published: October 2023

We aim to compute macroseismic parameters (location and magnitude) using the BOXER code for the first time on the citizen testimonies, that is, individual intensity data points (IDPs) at the global scale collected and made available by the LastQuake system of the European–Mediterranean Seismological Centre (EMSC). IDPs available for different earthquakes are selected to eliminate those that are geographically inconsistent with most data; then they are clustered spatially based on various methods. For each cluster with at least three IDPs, a macroseismic data point (MDP), corresponding to an intensity value assessed for given localities as in classical macroseismic studies, is computed by various central tendency estimators (average, median, and trimmed averages). Finally, macroseismic parameters are obtained by MDP distribution using two location methods of BOXER code. For each earthquake, we used raw and corrected intensities and 132 different combinations of grouping methods, estimators, and BOXER methods. We assigned a ranking to the combinations that best reproduce instrumental parameters and used such a ranking to select preferred combinations for each earthquake. We analyzed retrospectively the reliability of the parameters as a function of time and space. The results are essentially identical using original and corrected intensities and show higher reliability for BOXER’s method 1 than for method 0; they are dependent on the geographical area, and generally improve over time and with the number of IDPs collected. These findings are useful for the future real-time analyses, and for evaluating the location and magnitude of earthquakes whenever a sufficient number of IDPs are available and with a distribution such that MDPs can be derived and the BOXER method applied.
ÖDEMELER DENGESİ’NDE TAŞIMACILIK FAALİYETLERİ PERFORMANSININ CRITIC-ARAS VE WASPAS YÖNTEMLERİYLE ANALİZİ: TÜRKİYE ÖRNEĞİ
Authors: YERDELEN KAYGIN Ceyda , KAHRAMANİ KOÇ Azize
Published: October 2023

Ödemeler dengesi, bir ülkenin dünyanın geri kalan ülkeleri ile olan mali işlemlerini kaydeden, gelişmiş ve gelişmekte olan ülkelerin ekonomik performansını etkileyen sistematik ve istatistiksel tablolar olarak tanımlanmaktadır. Dünya ekonomisinin gelişimini etkileyen temel unsurların başında uluslararası arenada mal ve hizmet alışverişinin aksamadan sürdürülebilmesi için taşımacılık faaliyetleri oldukça önemli bir konumdadır. Bu çalışmada Türkiye’nin 2012-2021 yılları arasındaki ödemeler dengesi’nde taşımacılık faaliyetlerine ait gelir ve gider kalemlerinin yıllara göre performansları Çok Kriterli Karar Verme Yöntemlerinden CRITIC, ARAS ve WASPAS Teknikleri ile analiz edilmiştir. CRITIC Analizi sonucunda Türkiye’nin ödemeler dengesi’nde taşımacılık faaliyetlerinin performanslarının ölçülmesinde en fazla önem derecesine sahip kriter yolcu taşımacılığı giderleri (0,2167) kriteri iken en az öneme sahip kriter ise navlun (yük taşımacılığı) geliri (0,1328) kriteri olarak belirlenmiştir. ARAS ve WASPAS Analizleri sonucunda Türkiye’nin ödemeler dengesi’nde taşımacılık faaliyetlerinin 10 yıllık performans sıralamasında en yüksek performansa sahip yıl 2013 iken en düşük performansa sahip yıl ise 2012 olarak tespit edilmiştir.
Real-Time Detection and Identification of Suspects in Forensic Imagery Using Advanced YOLOv8 Object Recognition Models
Authors: Karakuş Serkan , Kaya Mustafa , Tuncer Seda Arslan
Published: October 2023

Rapid advancements in artificial intelligence, machine learning, deep learning, coupled with easy access to high-capacity processing hardware, expansive organized datasets, and the evolution of artificial intelligence algorithms, have extensively influenced numerous fields. Digital Forensics is one such discipline where the application of artificial intelligence has been significantly amplified in recent years. The analysis of extensive image and video files derived from forensic evidence presents challenges in terms of time efficiency and accuracy. To surmount these challenges, artificial intelligence models can be employed to perform identification and classification processes on these data, thus expediting the resolution of forensic cases with enhanced precision. In the current study, state-of-the-art pre-trained YOLOv8 object recognition models - nano, small, medium, large, and extra-large - were utilized. These models were trained on the Wider-Face dataset with the objective of identifying suspects from images and videos sourced from digital materials in the field of digital forensics. The models achieved mean Average Precision (mAP) values of 97.513%, 98.569%, 98.763%, 98.775%, and 99.032% respectively. The YOLOv8 architecture demonstrated superior performance, outperforming the YOLOv5 architecture by a margin of 7.1% to 8.8%. To aid digital forensic experts in the detection and identification of suspicious individuals, a desktop application capable of real-time image analysis was developed.
A Randomized Control Trial to Compare the Onset and Duration of Sensory and Motor Blockade with Intrathecal Isobaric Ropivacaine versus Isobaric Ropivacaine-Clonidine for Infraumbilical Surgeries
Authors: Ramachandran Haripriya , Gogate Vandana , Kumar Shailesh
Published: October 2023

Background: To investigate the onset and duration of sensory and motor blockade in isobaric 0.75% Ropivacaine and isobaric 0.75% Ropivacaine - Clonidine in patients undergoing infra umbilical surgeries.
One year double-blinded randomized controlled trial.
Methods: A total of 70 patients undergoing infra umbilical surgeries were allocated into two groups namely, Group I (n=35; Patients received 3 ml of isobaric 0.75 % ropivacaine intrathecally) or Group II (n=35; Patients received 3 ml of isobaric 0.75 % ropivacaine + 15 mcg of clonidine intrathecally). Onset and duration of Sensory and motor block and hemodynamic parameters were noted and compared.
Results: The demographic parameters were comparable in both groups. The onset of sensory block was similar in both groups but the duration of sensory block was prolonged in group II (191.7±19.21 minutes) than in group I (180.8 ±13.08 minutes). The motor block onset was faster in group II (11.4±2.29 minutes) than in group I (13.6±2.29 minutes). Duration of motor block was prolonged in group II (271.3±18.32 minutes) than in group I (224.5±16.46 minutes).
Conclusion: The addition of clonidine to 0.75 % isobaric ropivacaine intrathecally prolonged the duration of sensory and motor block but with no effect on the sensory onset but the faster onset of the motor block with no significant hemodynamic changes.
Evaluation of the Efficacy of Intraperitoneal Instillation of Ropivacaine with Dexmedetomidine Versus Ropivacaine with Ketamine for Post Operative Pain Relief following Laparoscopic Cholecystectomy: A Randomized Controlled Study
Authors: Kapoor Ruchi , Dua Steffi , Saxena Ashok Kumar , Narayan Shubham
Published: October 2023

Background: Adjuvants are added to intraperitoneal local anesthetics to prolong analgesia however no study compares Dexmedetomiditine with Ketamine as adjuvant to Ropivacaine for laparoscopic cholecystectomy.
To compare efficacy of intraperitoneal instillation of Ropivacine with Dexmedetomidine versus Ropivacaine with Ketamine for postoperative pain relief following laparoscopic cholecystectomy.
Methods: Sixty patients ASA I and ASA II undergoing laparoscopic cholecystectomy were  randomly allocated in three groups and received Ropivacaine 0.2 % (group R), Ropivacaine 0.2 % alongwith Dexmedetomidine 0.7 micogrms/ kg (group RD) and Ropivacaine with Ketamine 0.5 mg/kg (group RK) to a total volume of 40ml.The primary outcome measured was time to request of rescue analgesia while secondary outcomes were post op numeric rating scale, total dose of rescue analgesia required in 24 hours and haemodynamic parameters in postoperative period.
Results: The median time to request of rescue analgesia was shortest in R group 55 [42.5-70] minutes followed by RK group 60 [50.50-72.50] and maximum in the group RD the time being 900 [86.25 -1440] minutes while haemodynamics remained stable in all the groups. Similar findings were seen for total demand of analgesia in 24 hours as well as NRS scale both static and dynamic which was measured periodically in the first 24 hours.
Conclusion: Dexmedetomiditine 0.7 micrograms per kg when used as adjuvant with Ropivacine is effective combination that prolongs duration than Ropivacaine alone or when used with Ketamine 0.5 mg per kg body weight  however total dose of rescue analgesia was significantly less in Ketamine  group compared to Ropivacine alone and least when Dexmedetomiditine is used as adjuvant.
Comparison of Landmark v/s USG Guided Technique for Internal Jugular Vein Cannulation in Adult Patients Undergoing Cardiac Surgery
Authors: Mahajan Man Bhavan , Verma Indu , Mahajan Rupali , Kateel Karthik
Published: October 2023

Background: Obtaining central venous access is the basic requirement in patients undergoing cardiac surgery. Use of ultrasound (USG) for accessing IJV cannulation, improves the success rate and reduces the number of complications that may arise due to blind approach. Through this study we aimed to compare landmark vs real time USG guided IJV cannulation techniques.
Methods: 190 adult patient’s undergoing cardiac surgery were randomly divided into two groups of 95 each. Patients in Group A (Landmark based approach) were being compared to Group B (USG based) in terms of – success rate, first attempt success rate, total cannulation time, number of attempts, complications and success rate among residents and consultants.
Results: Success rate obtained in Group A was 89.4% compared to 100% in group B (P = 0.001). First attempt success rate was 67.36% in group A and 91.57% in group B (P < 0.001). Group B showed less number of attempts. Total cannulation time in group A (252.2 ± 66.4) sec was significantly higher (P<0.001) than group B (182.5 ± 40.39) sec. Rate of complications such as hematoma formation and carotid artery puncture were also significantly higher in group A.
Conclusion: The real time USG guided IJV cannulation is better technique than Landmark guided approach as it has significantly higher success rate, reduces the number of attempts, reduces the total time for cannulation and decreases the rate of complications. Also, success rate even increases among junior residents with the use of USG.
Polio Still Haunts Us With It's Sequalae
Authors: Shrestha Kajal , Singh Pankaj , Dagar Loveneesh
Published: October 2023

The Article Abstract is not available.
Crucial role of corticotropin-releasing hormone, corticotropin-releasing hormone-binding protein, mir-200c, and mir-181a in preterm delivery: A case-control study
Authors: Mazaheri Mahta , Ardakani Ehsan Mohiti , Forouzanfar Mohsen , Mojibian Mahdieh , Jafarinia Mojtaba
Published: October 2023

Background: Preterm birth before 37th wk of gestation is called premature birth. Corticotropin-releasing hormone (CRH) and CRH-binding protein (BP) act on various maternal and fetal tissues during pregnancy, such as the myometrium, which regulates the transition from the dormant phase of the uterus to the active phase. Studies have shown that mir-200c and mir-181a interact with CRH and CRH-BP.
Objective: The present study aimed to investigate the expression of mir-200c, mir-181a, CRH, and CRH-BP in women with a history of preterm birth.
Materials and Methods: In this case-control study, the gene expression level of mir-200c, mir-181a, CRH, and CRH-BP in placental tissue samples obtained from 48 women with a history of preterm labor was assessed in the Mojibian hospital of Yazd, Iran, from January to March, 2023. Differences between mir-200c, mir-181a CRH, and CRH-BP gene expressions among cases and controls were assessed.
Results: The outcomes indicated that the expression of CRH increased with going on to the regular parturition time (p < 0.001). While outcomes indicated, CRH-BP decreased with going on to the regular parturition time (p < 0.001). In addition, the results showed that the expression of mir-181a increased and mir-200c decreased with approaching the normal delivery time (p < 0.001).
Conclusion: In conclusion, the expressions of mir-200c, mir-181a, CRH, and CRH-BP were dissimilar in different weeks of gestation. It could be proposed to use mir-200c, mir-181a, CRH, and CRH-BP as biomarkers to weigh the exact delivery time, which could minimize the side effects of preterm labor for the mother and fetus.
Key words: CRH, CRH-BP, mir-200c, mir-181a, Preterm labor.