bluuebunny/crossref_metadata_2025 huggingface dataset:
The Associations of Gut Microbiota Metabolites with Blood Lipids and the Effect of Rosuvastatin Therapy on Them
Authors: Xiong Xiaowei , Zhou Jian , Fu Qiang , Xu Xiaowei , Wei Shaobin , Yang Shenghua , Chen Buxing
Published: November 2021

Background: Gut microbiota is contributed to the variations of blood lipids, and statins are found to affect the gut microbiota compositions. The aims of this study were to evaluate the associations of trimethylamine N-oxide (TMAO) and related precursors with blood lipids and the effect of rosuvastatin therapy on them.Methods: Totally 112 patients with suspected cardiovascular disease and received regular rosuvastatin therapy were enrolled in this study previously. The TMAO, choline, carnitine, betaine and γ-butyrobetaine (γBB) levels of the patients were analyzed by stable isotope dilution liquid chromatography-tandem mass spectrometry (LC/MS/MS), and the associations between them and blood lipids were analyzed by statistical methods.Results: Plasma TMAO was correlated with triglyceride positively (r=0.303, p<0.05) and high density lipoprotein cholesterol (HDL-c) negatively (r=-0.405, p<0.001). Plasma betaine was correlated with low density lipoprotein cholesterol negatively (r=-0.308, p<0.01). After adjustment of sex, age, body mass index, blood lipids and concomitant diseases, the association between TMAO and HDL-c was still significant (p<0.05). Besides, the correlation between TMAO and HDL-c still existed after rosuvastatin therapy (r=-0.253, p<0.01). Rosuvastatin therapy could decrease TMAO levels and increase carnitine, betaine and γBB levels significantly when it lowering the blood lipids.Conclusions: These results indicated that TMAO and related precursors were associated with blood lipids significantly, especially HDL-c. Rosuvastatin therapy not only affects the blood lipids, but also influences the levels of TMAO and related precursors.Trail registration: This study was retrospectively registered at http://clinicaltrials.gov/ (NCT02305862).
The role of agroforestry intensification in biodiversity conservation in western Ethiopia
Authors: Likassa Ebisa , Bekele Tamrat , Nemomissa Sileshi
Published: November 2021

Background

Human mismanagement of natural habitats caused the great loss of biodiversity and ecosystem because of their conversion into modified landscapes. On the other hand, agroecosystems are playing vital role in terms of retaining and conserving certain overstorey trees and associated perennial crops in addition to the small fauna. The main objective of this study was to assess the diversity of woody species and vegetation structure in three coffee systems across an increasing farmers’ management intensity in selected research areas of western Wollega, Ethiopia. A total of 72 samples (24 per each management systems) were purposively selected from three districts based on the dominant coffee production system and the level of coffee production, which supposed to affect the diversity of tree species for collecting data on woody species. Plant specimens were collected following standard herbarium technique and identified in the field and at national herbarium.
Results

A total of 50 woody species were identified. The most abundant shade tree in coffee agroecosystems was Cordia africana. The nonmetric multidimensional scaling (NMDS) ordination and Sorensen distance-based ordination demonstrated that plots of the same coffee system were almost maintained similar species composition and abundance. However, no similar pattern was observed between the coffee systems, except the small overlap in species composition between plantation coffee and garden coffee systems. Diversity of woody species was significantly different among the coffee management systems (P <.0001). Similarly, some of the structural parameters like density, basal area, and shade significantly reduced along the increased coffee management intensity.
Conclusions

The study found evidence that the intensification of coffee management was not always the source of biodiversity loss; rather, it is an opportunity for conservation of the locally threatened higher plants. Incorporation of coffee shrubs in the degraded lands or remnant forest patches, integrating coffee in the massive afforestation/tree planting programs, and using multipurpose trees in afforestation can be used as an alternative strategy for overstorey plant conservation
A Finite Element Analysis of the Effects of Different Internal Fixation Strategies and Cage Implantation Methods on the Biomechanics of the Lumbar Spine
Authors: Han zhenchuan , Ren Bowen , Mao Keya , Tang Peifu , Zhang Long , Ma Chao , Liu Jianheng
Published: November 2021

Objective: Providing the biomechanical evidences to the surgeons on the internal fixation strategy and Cage implantation method in minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) by the finite element analysis (FEA).Methods: Firstly, based on the common MIS-TLIF surgical methods, three surgical models with different internal fixation strategies and Cage implantation methods were established. The surgical models simulated the physiological activities of the lumbar spine to evaluate the range of motion (ROM) of lumbar spine, the peak stress and the overall stress of the internal fixation system and Cage.Results: The results of the study show that the ROM of the surgical model has decreased significantly under all working conditions, and the decrease range is between 71.07-97.53%. The peak stress of the internal fixation system range was 48.56 to 100.09 MPa in Model-A, 58.10 to 136.05 MPa in Model-B, and 83.26 to 189.81 MPa in Model-C. Especially in the three working conditions of left lateral bending (LLB), left rotation (LR), and right rotation (RR), the peak stress of the internal fixation system of Model-C is 1.80 , 2.07, 1.79 times of Model-A and 2.05 , 1.64, 2.28 times of Model-B. The peak stress of Model-C Cage is significantly lower than Model-A and Model-B under all working conditions.Conclusion: Although the strategy of unilateral pedicle screw + lamina articular process screw + Cage horizontal implantation has the least Cage stress, there is a higher risk of internal fixation fail. Comprehensive evaluation, the surgical strategy of bilateral pedicle screw + Cage horizontal implantation has the best performance, and has the potential to become the standard implantation strategy of MIS-TLIF.
Nutrition Supplementation Practices of Recreational Gym Users in Uganda’s Capital City: A Cross Sectional Study
Authors: Muwonge Haruna , Makubuya Timothy , Lubega Samuel K. , Zavuga Robert , Mukana Roland S.
Published: November 2021

Background: This study focused on investigating the prevalence of nutritional supplement (NS) usage, establishing their source and the motivating factors for the usage of NS among Gym users in Kampala city, Uganda.Methods: The study employed a cross-sectional research design. Multistage random sampling techniques were used to select 45 gym users among the 5 divisions that constitute Kampala city. Data were collected using questionnaires and analyzed using SPSS Version 26, where means, SD, frequencies and percentages were obtained. Chi-square tests were used for categorical comparisons between variables. Results: The results showed that there were more male participants (62.2%) than female participants (37.8%). The majority (76.9%) of gym users obtained NS from retail stores such as pharmacies, (10.2%) from their sports coaches, (7.7%) nutritionists/dieticians, and (5.1%) from team mates. Non-professional gym users (62.3%) reported higher levels of energy drink consumption than professional gym users (26.7%). The consumption of vitamins, herbal products and proteins was also considerably high. We also identified coaches/trainers (30.8%) as the main source of information, followed by nutritionists/dieticians (23.1%) and online websites (20.5%). Most gym users strongly agreed that supplements increase endurance training, increase strength, and make one healthier.Conclusions: The prevalence of nutritional supplement usage among gym users was high, with energy drinks and herbal products being the most preferred supplements.
Co-evolutions of terrestrial temperature and seasonal precipitation from the latest Pleistocene to the mid-Holocene in Japan: carbonate clumped isotope record of a stalagmite
Authors: Kato Hirokazu , Mori Taiki , Amekawa Shota , Wu Chung-Che , Shen Chuan-Chou , Kano Akihiro
Published: November 2021

Quantitative paleotemperature reconstruction is a challenging and important issue in terrestrial paleoenvironmental studies, for which carbonate clumped isotope (Δ47) thermometry is a promising approach. Here we analyzed Δ47 values from 68 layers of OT02 stalagmite from Ohtaki Cave in central Japan, covering two separate time intervals (2.6–8.8 and 34.8–63.5 ka) to reconstruct temperature and meteoric d18O records. The average Δ47 temperature of the Holocene portion of this stalagmite was 16.3℃ ± 5.6℃, 6.6℃ ± 7.2℃ higher than the average of the latest Pleistocene portion, which was 9.7℃ ± 4.6℃. Δ47 thermometry also revealed that the coldest intervals (5℃–10℃) correspond to the Heinrich cooling events H4–6, and the warmest interval (up to 19.9℃ ± 6.0℃) in middle Holocene (approximately 6–5 ka) accompanied by the Hypsithermal climate optimum. We also reconstructed past meteoric δ18O by subtracting the temperature effect from stalagmite δ18O. Average meteoric δ18O was less negative in the Holocene (8.22‰ ± 0.99‰ VSMOW) than in the latest Pleistocene (8.81‰ ± 0.84‰). Over centennial timescales, meteoric δ18O was more negative during colder periods, such as Heinrich cooling events and the cooling event around 7 ka, and less negative in warmer periods, such as Hypsithermal warming. These relations indicated co-evolution of terrestrial paleotemperature and paleoprecipitation. A temperature dependency of 18O fractionation from water to vapor is a likely reason for the negative correlation between temperature and meteoric δ18O. Additionally, it is possible that increasing lower δ18O precipitation from East Asian winter monsoon (EAWM) has decreased the averaged meteoric δ18O in colder periods. These temperature effects on meteoric δ18O occur in opposite directions to fractionation between water and the stalagmite δ18O, explaining the small amplitudes of changes observed in the δ18O of Japanese stalagmites.
A Pyroptosis-Associated Signature Plays a Role in Prognosis Prediction And Indicating Infiltration in Immune Microenvironment in Clear Cell Renal Cell Carcinoma
Authors: Li Zhiyuan , Xia Zhinan , Yu Yipeng , Cai Licheng , Jian Wengang , Wang Tengda , Xue Wei , Wang Xingyuan , Wang Bowen , Zhang Peng , Yao Wenhao , Zhang Cheng , Wang Chunyang
Published: November 2021

Background: About 90% renal malignancies are RCCs (renal cell carcinomas) and the main subtype in histology is ccRCC (clear cell RCC). In recent years, pyroptosis was considered as a kind of inflammation-related programmed cell death, which played a part in the invasion, metastasis and proliferation of tumor cells, thereby influencing tumor prognosis. Nonetheless, the expression level of pyroptosis-associated genes in RCCs and its relationship with prognosis are still not clear. Results: In our research, 44 regulators for pyroptosis were identified which were expressed differentially between normal kidney and ccRCC tissues. ccRCC cases were categorized into 2 subgroups with a significant difference between them in OS (overall survival) according to the DEGs (differentially expressed genes). The prognostic value of pyroptosis-associated genes was assessed as a signature based on the cohort of TCGA (The Cancer Genome Atlas). Following Cox regression with DEGs and LASSO (least absolute shrinkage and selection operator), a 6-gene signature had been set up and all the ccRCC cases in the cohort of TCGA were categorized into LR (low-risk) group or HR (high-risk) group (P < 0.001). In combination with clinical features, risk scores were considered as a predicting factor of OS in ccRCC cases. KEGG (Kyoto Encylopedia of Genes and Genomes) and GO (Gene ontology) analyses implied increased immunity and enrichment of genes related to immunity in the HR group. Conclusions: Our findings indicated that the genes related to pyroptosis had an important role in tumor immunity, which were potentially used to predict the prognosis of ccRCCs.
Study On Coronary Dissection Complication Caused by Uneven Rotational Atherectomy Due To Guidewire Bias for Severe Calcified Lesions
Authors: Ye Fei , You Wei , Zhang Hong-li , Xu Tian , Meng Pei-na , Zhou Yu-he , Guo Ya-jie , Nong Jia-cong , Zhao Yan-fang , Wu Xiang-qi , Wu Zhi-ming , Yin De-lu
Published: November 2021

BACKGROUND
In the treatment of coronary calcification by rotational atherectomy (ROTA), guidewire bias is often considered to lead to procedure associated coronary dissections or perforations. However, the actual meaning of guidewire bias is unclear, though it usually refers to the cross-section location of the intravascular imaging (IVI) catheter in the coronary artery.
OBJECTIVES
This study tentatively explores the quantitative criteria in optical coherence tomography (OCT) imaging of guidewire bias which may cause ROTA induced coronary dissection.
METHODS
A total of twenty-one patients with severe calcified coronary lesions who has undergone ROTA treatment were enrolled in our study. These patients were detected by OCT successfully pre- and post-ROTA. All the observational coronary segments were analyzed cross-sectionally at every mm interval after manual coregistration of OCT imaging pre- and post-ROTA. ROTA related coronary dissection was the primary endpoint.
RESULTS
A total of 388 OCT cross-sectional images were effectively measured and analyzed for distribution and characteristics of plaque and OCT catheter location pre-ROTA, and the presence or absence of coronary dissections post-ROTA after manual coregistration. According to the receiver operating characteristic (ROC) analysis, distance from the center of OCT catheter to media at the bias direction (Dcmb) (area under the curve (AUC): 1.000, p<0.001, 95% confidence intervals (CI): 0.999 to 1.000) and touch angle (AUC: 0.988, p<0.001, 95%CI: 0.968 to 1.000) had a higher correlation with ROTA-related coronary dissection with the corresponding cutoff value of 0.720mm and 98.2º significantly.
CONCLUSIONS
Dcmb and touch angle detected by OCT are two very valuable and convenient independent predictors of ROTA-related coronary intimal dissections caused by guidewire bias.
Prevalência das alterações sistêmicas dos pacientes atendidos pela Clínica de Odontologia do Centro Universitário Ruy Barbosa
Authors: Souza Kaíque Carvalho de , Queiroz Anna Raquel Gomes de Araújo , Dias Rosane Borges , Siqueira Daniele Veiga da Silva , Leitão Thaís Feitosa de Oliveira , Silva Virgínia Dias Uzêda e
Published: November 2021

Complicações médicas, apesar de raras, podem ocorrer durante o atendimento odontológico, os pacientes portadores de alterações sistêmicas são os mais propensos a esta ocorrência, portanto requerem um atendimento especial pelo cirurgião-dentista. Objetivo: Avaliar o perfil das condições sistêmicas dos pacientes atendidos na clínica de Odontologia do Centro Universitário Ruy Barbosa. Metodologia: Foi realizado o levantamento dos pacientes atendidos na Clínica de Odontologia do Centro Universitário Ruy Barbosa - Wyden no período de 2016.2-2019.1. Os dados foram coletados a partir dos prontuários clínicos dos pacientes que se submeteram a atendimento no serviço da Faculdade e foram originalmente preenchidos pelos alunos de Graduação dessa instituição totalizando 719 prontuários. Os prontuários preenchidos incorretamente ou com dados incompletos foram contabilizados como incompletos. Os resultados foram analisados descritivamente, por porcentagem na presença de alterações sistêmicas dos pacientes encontrados no prontuário. Resultados: Do total dos prontuários analisados as condições sistêmicas mais prevalentes foi a hipertensão com 81 (27,55%) casos encontrados, seguido por anemia com 69 (23,55%) casos, alergia medicamentosa com 41 (17,9%) casos, diabetes e coagulopatia com 29 (9,9%) casos cada encontrados. Conclusão: As alterações mais prevalentes foram a hipertensão, anemia, alergia medicamentosa e diabetes, assim, predominando nas mulheres e na faixa etária entre 40 a 49 anos. Sendo de fundamental importância a avaliação criteriosa dos pacientes durante a consulta odontológica para identificação de possíveis problemas que possam alterar o plano de tratamento.
Hiperpigmentação oral em pacientes vivendo com HIV: relato de dois casos clínicos
Authors: Oliveira Bezerra Hanna Isa de , Gonzaga Amanda Katarinny Goes , Dias Ana Carolina Macedo da Silva , Oliveira Moisés Morais de , Silva Jade Zimmermann e , Oliveira Patrícia Teixeira de , Medeiros Ana Miryam Costa de
Published: November 2021

Introdução: As lesões orais estão entre as primeiras manifestações clínicas da infecção por HIV, podendo indicar também sua progressão. Dentre elas, inclui-se a hiperpigmentação oral, que também pode ser oriunda do uso de medicações da terapia antirretroviral (TARV). Objetivo: Relatar dois casos clínicos de hiperpigmentação oral em pacientes vivendo com HIV, sendo um deles submetido à TARV e outro sem tratamento. Relato de caso: Caso 1 - Paciente do sexo masculino, 30 anos, ex-etilista, vivendo com HIV, apresentou manchas amarronzadas assintomáticas no lábio inferior com evolução de cinco meses. Após exame clínico, a TARV foi atribuída como causa das lesões. Caso 2 - Paciente do sexo masculino, 55 anos, vivendo com HIV, ex-tabagista, diagnosticado com tuberculose, apresentou hiperpigmentações em mucosa jugal bilateralmente, além de candidose eritematosa e pseudomembranosa no palato duro e dorso lingual, respectivamente. Realizou-se biópsia incisional da região pigmentada, confirmando o diagnóstico de hiperpigmentação melânica. O paciente não fazia TARV há 05 anos. Conclusão: Alterações bucais em pacientes vivendo com HIV podem ser decorrentes da própria imunossupressão ou estarem associadas ao uso dos antirretrovirais. É imprescindível que o cirurgião-dentista as conheça para que esteja apto a reconhecer as manifestações clínicas desta infecção ou de sua progressão, oferecendo assim um diagnóstico correto e precoce, bem como conduta clínica correta frente a esses casos.
Multicenter investigation of predictors to self-report vaccination and seroprotection against Hepatitis B among healthcare workers
Authors: Morcerf Vivianne Lins Ebrahim , Lacet Celina Maria Costa , Largura Álvaro , Silva Evanio da , Barbosa Kevan Guilherme Nóbrega , Ferreira Sonia Maria Soares , Abreu Silvio Romero de Oliveira
Published: November 2021

Objective: The Healthcare Workers (HCWs) are professionals with occupational exposure risk to Hepatitis B virus (HBV). Vaccination status has been widely explored; however, few investigations had confirmed the HBV immunity by serological test. Method: We performed a multicenter study based on a dual approach to understand the predictive factors of vaccination and seroprotection to HBV among HCWs. A cross-section design investigation was carried out among 371 workers from Alagoas state (Brazil); all of them from the public health service. Multiple Poisson Regression Models were constructed using vaccination and seroprotection as dependent factor. Results: The overall self-report of vaccination was 70.4% and the confirmation by immune response was 72.2%. Three predictive factors were associated with vaccination: education level; use of the PPE during work, and personal serological evaluation. Two predictive factors were associated with seroprotection: education level and use of the PPE during work. Conclusion: Our findings showed some evidence that almost one third of healthcare workers were not immune to HBV, and factors such as education and use of the protective equipment can predict the susceptibility to HBV.
O papel do cirurgião dentista na equipe multiprofissional da Atenção Básica em Saúde, após 19 anos de sua implantação
Authors: Gurgel Filho Artur Antônio Guedes , Amaral Regiane Cristina do
Published: November 2021

A Odontologia no Brasil, por muitos anos, passou por modelos assistenciais (Incremental e Simplificado). Houve predomínio do desempenho em um modelo técnico e curativo, direcionado a grupos como escolares. Com o advento do SUS (Sistema Único de Saúde) e posterior criação do Programa Saúde da Família (PSF) em 1994, houve inserção da odontologia na Estratégia Saúde da Família (ESF) no ano 2000. Objetivo: O presente estudo teve como objetivo analisar a percepção dos profissionais que trabalham na ESF com a participação do cirurgião-dentista (CD) na ESF e da equipe do NASF (Centro de Apoio à Saúde da Família) após 19 anos de integração com o SUS. Metodologia: Este estudo transversal foi realizado através de questionários aplicados ao CD, membros da equipe de referência (ESF) e apoio (NASF) da Atenção Básica. Os questionários foram compostos por 11 perguntas, diferentes para as categorias profissionais, sendo auto administrados. Resultados: foram entrevistados 89 profissionais pertencentes às Unidades de Saúde de 15 CRES (Saúde Regional), 69 do sexo feminino e 20 do masculino, 58,4% com idade entre 20 e 36 anos e 27% com idade entre 36 e 50 anos. Dos profissionais entrevistados, 94% consideraram relevante a interação do cirurgião-dentista com a ESF e 80% perceberam a atitude do CD ou algum aspecto da liderança em ações coletivas. Conclusão: Após 19 anos de integração da saúde bucal, equipes na atenção básica do SUS, observou-se a incorporação do dentista com aspectos positivos.
Imaginologia odontológica no processo de identificação humana: relato de caso pericial
Authors: Gadelha Milena Norões Viana , Cavalcanti Rafaella Bandeira de Melo Souza , Gadelha Marília Norões Viana , Stibich Christian Abreu , Sousa Mathias Antonio Costa de , Morais Ivynna Martins Marinho , Lima Carolina Barbosa Lopes de , Ramos Joab Cabral , Gonzalez Ana Tatiana , Rocha Julierme Ferreira , Oliveira Filho Abrahão Alves de , Figueiredo Camila Helena Machado da Costa , Almeida Manuella Santos Carneiro
Published: November 2021

Introdução: A imaginologia odontológica é de grande relevância para a identificação humana, sendo frequentemente utilizada pela Odontologia Legal para este fim. O correto arquivamento dos exames de imagem nos prontuários dos pacientes permite a comparação de dados ante e post mortem. Objetivo: O presente trabalho objetivou descrever a determinação da identificação de um indivíduo carbonizado por meio da imaginologia odontológica. Relato de caso: As documentações fornecidas pela família da vítima foram uma foram confrontadas com aquelas obtidas pelas radiografias periapicais dos dentes realizadas pelos peritos. Foram encontrados os seguintes pontos coincidentes após o confronto das informações entre os exames ante-mortem e post-mortem: giroversão dos dentes 34, 43 e 44; aposição de dentina secundária nas câmaras pulpares dos dentes 36, 37, 46, 47 e 48; cárie oclusal do dente 36 e trabeculado ósseo com características anatômicas individuais em região de molares inferiores nos lados direito e esquerdo, resultando em uma identificação positiva. Conclusão: Assim, conclui-se que o confronto entre as radiografias ante-mortem e post-mortem é uma ferramenta fundamental no processo de identificação em Odontologia legal. Entretanto, essa técnica apenas pode ser aplicada com a existência de arquivos anteriores para comparação. Logo, é importante enfatizar a importância da manutenção e do correto arquivamento de exames de imagens odontológicos obtidos durante o tratamento do paciente, pelos cirurgiões-dentistas.
Association between domestic violence and oral health problems in children and adolescents: a systematic review
Authors: Nascimento Michele Gomes do , Costa Nataly Pereira da , Colares Viviane
Published: November 2021

Domestic violence has a negative impact on development, general health, and quality of life of children and adolescents. This study aimed to revise knowledge regarding the consequences on oral health and its related outcomes of children and adolescents exposed to domestic violence. We conducted this systematic review in line with Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement, adhering to a published protocol in PROSPERO. This review systematically searched the literature using the MEDLINE, PsycINFO, LILACS, SciELO databases and Grey Literature, for articles published in English, Portuguese, and Spanish, with no publication date limits. Quality of studies was assessed using New Castle Ottawa scale and its modified version. All process was carried out independently by two researchers. Fourteen studies were included. Nine studies were cross-sectional, four were case-control, and one was a retrospective cohort. All studies included in this review found a higher risk of having some oral health problem and being exposed to some type of domestic violence. The main oral health problems associated with some type of violence were caries experience (decayed, missing and filled teeth), poor self-perceived oral health, malocclusion, poorer oral health related quality of life, poorer oral hygiene, and early childhood caries experience. Important methodological advancements are needed to better understand potential moderators.
Qualidade de vida relacionada à saúde em indivíduos portadores de Disfunção Temporomandibular: revisão integrativa
Authors: Silva Jadson Mathyas Domingos da , Silva Douglas Ferreira da , Lins Márcio Macário da Silva , Raposo Mariana Josué
Published: November 2021

Objetivo: Analisar a literatura a respeito da correlação entre disfunção temporomandibular (DTM) e qualidade de vida relacionada à saúde (QVRS) em indivíduos portadores da disfunção. Metodologia: Trata-se de uma revisão integrativa de literatura que utilizou os descritores: “articulação temporomandibular”, “qualidade de vida” e “odontologia” inicialmente isolados e posteriormente cruzados usando-se o operador boleano AND. As bases de dados consultadas foram o PubMed e o SciELO. Incluiu-se artigos completos e gratuitos que retratassem a temática proposta nos anos de 2010 a 2020. Resultados: Incluiu-se 16 artigos que contemplavam a questão da pesquisa. A literatura consultada sugere que a DTM impacta negativamente na QVRS por seus sintomas interferirem no convívio social, afetivo e na realização de atividades de vida diária, sendo a DTM muscular a que traz maiores prejuízos psicológicos ao indivíduo. Conclusão: Esta disfunção impacta negativamente na qualidade de vida relacionada à saúde no bem-estar físico e psicossocial, sendo a dor, limitação funcional e distúrbios de saúde mental as principais características relacionadas a essa correlação.
Abordagem holística durante a gestação: alterações sistêmicas e suas repercussões na saúde bucal
Authors: Foratori-Junior Gerson Aparecido , Pereira Priscilla Ramos
Published: November 2021

Diversas alterações fisiológicas, imunológicas e hormonais ocorrem durante a gestação e quando associadas aos comprometimentos sistêmicos materno podem ter efeito sinérgico na saúde bucal das gestantes. O objetivo deste trabalho foi sintetizar as evidências científicas atuais de maior qualidade acerca da associação entre alterações sistêmicas e saúde bucal durante a gravidez. No período de agosto/2020 a março/2021, as seguintes bases de dados foram acessadas: EMBASE, SCOPUS, MEDLINE (Entrez PubMed), Web of Science, BVS/LILACS, e SCIELO. Foram incluídos estudos publicados entre janeiro/2000 a março/2021 em espanhol, inglês e/ou português. Devido às alterações imunológicas e hormonais da gravidez, a gengivite e a periodontite são as doenças bucais de maior prevalência nesse período. As alterações sistêmicas durante a gestação que comumente se associam à prejuízos na cavidade bucal são: anemia, sobrepeso/obesidade, ganho ponderal gestacional excessivo, diabetes mellitus e hipertensão arterial. Ademais, os acometimentos sistêmicos e periodontais na gestação podem prejudicar a saúde dos recém-nascidos. Entretanto, a obesidade e periodontite, apesar de estarem associadas, podem apresentar efeitos antagônicos na saúde dos recém-nascidos, visto que a obesidade se associa a macrossomia e a periodontite materna se associa à prematuridade e ao baixo peso ao nascer. Diante do exposto, conclui-se que diversas alterações sistêmicas se associam à piores parâmetros de saúde bucal durante a gravidez e esses fatores, conjuntamente ou isolados, podem resultar em efeitos perinatais adversos, afetando a saúde das mães e dos bebês.
Comparison of Salt Exclusion in Muscadine and Interspecific Hybrid Grapes Using a Greenhouse Screening Procedure
Authors: Hillin Danny , Helwi Pierre , Scheiner Justin J.
Published: November 2021

Bunch grapes (Euvitis) are classified as moderately salt-tolerant. However, little is known about the salt tolerance of muscadine grapes (Vitis rotundifolia). The objective of this research was to evaluate the salt exclusion capacity of muscadine grapes relative to common bunch grape rootstocks and hybrid winegrapes using a greenhouse screening assay. In two separate experiments, 31 muscadine, six bunch grape rootstocks, and five hybrid winegrape cultivars were irrigated daily with a 25-mm sodium chloride salt solution for a period of 14 d, followed by a destructive harvest to determine sodium (Na) and chloride (Cl) concentrations in root and shoot tissues. Generally, the muscadines studied exhibited a greater range of salt concentration relative to bunch grape rootstocks. Total tissue (shoot and root) salt varied by 250% and 430% across muscadines and by 180% and 190% across bunch grape rootstocks for Na and Cl, respectively. Despite the wider range, muscadine grapes expressed significantly less leaf necrosis than the bunch grape rootstocks. The most effective salt-excluding muscadines, ‘Janebell’, ‘Scuppernong’, ‘Late Fry’, and ‘Eudora’, were not distinguishable from the bunch grape rootstocks [‘Paulsen 1103’ (1103P), ‘Ruggeri 140’ (140Ru), ‘Schwarzmann’, ‘Millardet et de Grasset 101-14’ (101-14 Mgt.), ‘Millardet et de Grasset 420A’ (420A), and ‘Matador’]. Overall, there was no discernable difference between the salt exclusion capacity of muscadine and bunch grapes. The hybrid winegrape ‘Blanc Du Bois’ displayed poor Na and Cl exclusion properties but showed only moderate leaf necrosis symptoms. In both experiments, ‘Blanc Du Bois’ accumulated more than two-fold higher root and shoot concentrations of Na and Cl compared with the best-performing rootstocks (1103P, 140Ru, 101-14 Mgt.), suggesting that ‘Blanc Du Bois’ could benefit from grafting if salinity is a limiting factor.
Marine Industry Automation Systems Simulation
Authors: M Dumitrescu
Published: November 2021

In a competitive economy, regarding competition between companies that have the same field of activity, the growth of productivity, the fast solving of malfunctions, the quality of services, all of these are very important factors. To stand up in front of these challenges, many companies appeal to high technology, although expensive, which can lead to a spectacular growth of work efficiency, in the same time improving quality of services. This paper describes the interaction between PLC, SCADA and the software PICS Pro for the dredging system of a ship and the realization of a graphic interface which simulates the behavior of the real system.
Process modeling for business management of online marketing campaigns through social media
Authors: M. A. M. Popescu
Published: November 2021

The online environment is becoming more competitive each day, and the consumer's journey is becoming more complex, going through several marketing channels on their way to buying. Social media networks environments facilitate access to information and at the same time contribute to creating an image, a perception of reality. Building and strengthening social media reputation are essential for companies in 2018. To have credibility, a company must create and maintain a good image across all the social networks it finds. The more transparent and sincerer through their communication, the easier it will be for brands to maintain their reputation and gain consumer confidence, which can be achieved through social media. The article presents the main social networks used by companies to create digital marketing campaigns. The authors illustrate the steps needed to set up audiences on Facebook, Instagram and Twitter, organizing the information in tables in order to be easier to track. BPM Software is used to design process models for these online marketing campaigns.
Optimal design for a cylindrical gear with inclined teeth
Authors: M TUROF
Published: November 2021

Designing is an act of creation, which is a technical activity carried out for productive purpose, and which aims to provide all the data necessary for the implementation of correlated material and financial means, a theme or an idea in practice. Depending on the operating conditions of the machines and their technological destination, optimum reliability, maintainability and ergonomics must be ensured from the design stage. For some areas where toothed gears are used, such as the aerospace industry, the automotive construction etc., reduced gear mass (volume) can be an important parameter to become an optimization criterion. This paper aims to study the gearing mass and proposes to minimize this function. 𝑀𝑔𝑒𝑎𝑟𝑖𝑛𝑔 = 𝑉𝑔𝑒𝑎𝑟𝑖𝑛𝑔 ∙ 𝜌𝑚𝑎𝑡𝑒𝑟𝑖𝑎𝑙 → 𝑚𝑖𝑛
Aspects on methods of assessing prelucrability through cold plastic deformation of metallic materials
Authors: A. Chioibas
Published: November 2021

In the field of cold pressing, the notion of machinability refers to the behavior of the material during deformation, the technological equipment and the machine. In this paper we presented the methods of estimating the behavior of the semi-finished material during processing.
Mathematical model for logistics base selection decision
Authors: E. Demirel
Published: November 2021

Logistics bases are defined as a particular region, in which all activities related to transport, logistics and distribution of goods, at both national and international level, is carried out by various operators. In this context, the goal of this study to choose the best available port to be developed as a logistics base in Turkey. A mathematical model called Analytical Hierarchy Process (AHP) model is used as a tool to determine the best location for logistics base in Turkey. After having a preliminary research for alternative locations, existing ports in Ambarlı/İstanbul, Samsun, Mersin and Aliağa/İzmir are designated as alternative bases. During this preliminary review, the existing facilities such as ports, transportation, infrastructure and their potential cargo capabilities to be handled are taken into consideration. In this model, total of five different sets of primary objectives/ choice criteria are defined. These are; current transportation capabilities and its connection with the hinterland, labor force to be employed in the base, current infrastructure capabilities, size of the area covered by the port, cargo potential to be handled in the base and number of the logistics companies in the region. In order to achieve much more accurate result, second and third level sub-objectives are also assigned for each first level objective such as transportation, labor, infrastructure, and area. To achieve a much more comprehensive picture, a sensitivity analysis for input parameters, such as transportation, is also applied. Further on this analysis, inputs (different preference values of transportation objectives) and outputs (port priority values) of this analysis are used to establish a Linear Regression Model for further predictions.
Influence of trim and rudder angle on ship handling
Authors: Alecu Toma
Published: November 2021

The purpose of this paper is to identify the influence of trim and rudder angle on ship handling. Studying this matter using all available means, actual power rating at different trim values was put at comparison, also pressure diagrams and speed diagrams were taken into consideration. Upon completion of the paper, the actual power variation graph was plotted against the angle of trim.
Comparison of CFD determined squat on sailing ship MIRCEA with empirical methods
Authors: P. S. Șerban
Published: November 2021

The paper presents a study of hydrodynamic parameters related to ship squat acting on sailing ship MIRCEA hull in shallow waters, using CFD methods. The vertical hydrodynamic forces obtained in ANSYS CFX were analysed in respect with various domain depths and ship’s speeds, but also used for squat calculations. In order to evaluate the reliability of previously determined squat, a comparison study was made with nine of the most common empirical formulae for calculating squat in open shallow waters, ranging from Barrass to Huuska or Eryuzlu and Hausser. Some of these methods offer good results and were often experimentally validated with scale models.
Sound propagation modelling in a lecture hall
Authors: T. Pazara
Published: November 2021

For lecture halls, intelligibility of speech is the most important aspect. To achieve a relative uniform distribution of sound among the listeners, a number of parameters must be taken into account. One method to speed up the design process of a lecture hall is to model the sound propagation in that room using computer acoustic software. In this paper, the authors have chosen a lecture hall from Naval Academy and made numerous simulations to discover what are the week points regarding the acoustics of this room. The acoustical parameters obtained from simulations are compared with the desired ones and a few remarks for the improvement of the room are made.
To reserves estimation of Khulj hot spring
Authors: Surmaajav D. , Ariunaa Ch.
Published: November 2021

The first prospect evaluation hydrogeological survey of underground mineral thermal waters formed by Khulj hot spring in Bulgan aimag, Mongolia was conducted in 1973. And since then no research has been conducted. However, in 2020–2021, the Governor of Bulgan aimag initiated a hydrogeological exploration study of Khulj spring in order to determine its mineral thermal water resources. The works were funded by the state budget. It was the first time that the mineral thermal water resources of Khulj spring were estimated and classified to the category B in accordance with the degree of geological and hydrogeological study. Conducted exploration works allowed to investigate and specify geological-structural, hydrogeochemical and hydrogeothermal features that determined the formation of the mineral thermal water deposit.
Occurrence of Tankhoy field coals in South Baikal bottom sediments
Authors: Khlystov O. M. , Vainer-Krotov A. V. , Kitaev A. V. , Pogodaeva T. V.
Published: November 2021

The purpose of the study is to describe the first finds of coal-bearing clays and coals in the bottom sediments of the southern basin of Lake Baikal and compare them with terrestrial coal-bearing deposits of the Tankhoy field. Comparative analysis of the lithological composition and colour of bottom sediments and terrestrial sections, as well as the concentration of organic carbon and conducted palynological analysis allowed their correlation. At the lake’s depth of 900 m the authors discovered a coal-bearing strata in situ (st 56), which later was stratigraphically correlated with the terrestrial coalbearing part of the Tankhoy suite. The fragments of coal found in bottom sediments basically along the entire Tankhoy field, especially bedrock coals on the underwater slope in South Baikal up to 1300 m deep prove the distribution of the coal-bearing part of the Tankhoy suite in the sublacustrine part of the lake throughout the entire slope (from 5 to 10 km offshore) and confirm the distribution area of the Tankhoy paleolake over a significant area of the contour of modern southern basin of Lake Baikal. The finds of coal-bearing strata on these and other various sub-bottom depths, i.e. under various pressure and temperature conditions, suggest that coals themselves and coal-bearing mudstones may be a generation facility of secondary microbial methane. This should be taken into account when searching for gas hydrocarbon and gas hydrate accumulations as well as assessing methane cycles in Lake Baikal.
Heat stress-induced changes in shoot and root characteristics of genotypes of tepary bean (Phaseolus acutifolius A. Gray), common bean (Phaseolus vulgaris L.) and their interspecific lines
Authors: Muñoz Ligia Carmenza , Rivera Mariela , Muñoz Jaime E. , Sarsu Fatma , Rao Idupulapati M.
Published: November 2021

Heat stress is a major limitation to grain yield in common bean (Phaseolus vulgaris L.). Tepary bean (Phaseolus acutifolius A. Gray) is better adapted to heat stress than common bean. Ten tepary bean accessions, four common bean genotypes and four interspecific lines involving P. vulgaris and P. acutufolius, P. coccineus and P. dumosus were evaluated for tolerance to heat stress conditions induced under greenhouse conditions and these were compared to plants grown under ambient temperatures. The high temperature treatment was 29 ±5 °C during the day and was >24 °C (up to 27 °C) during the night, while the ambient temperature (AT) treatment was 25 ±5 °C during the day and 19± 2 °C at night. The genotypic differences were evaluated for morpho-physiological characteristics of shoot and root and also yield components. The Genotype and Genotype × Temperature interactions were significant for all shoot and root morpho-physiological characteristics evaluated. Higher temperature (HT) significantly affected leaf photosynthetic efficiency, total chlorophyll content, and stomatal conductance. The effect was positive or negative, depending on the genotypes. Tepary accessions showed reduced total chlorophyll content, while common bean genotypes and the interspecific lines were less affected. Tepary accessions also showed reduced stomatal conductance, but increased leaf photosynthetic efficiency under HT. Common bean genotypes increased stomatal conductance and decreased leaf photosynthetic efficiency. High temperature decreased total root length, specific root length and pod biomass compared to ambient conditions, but there was no marked effect on pollen viability of the tested genotypes. The superior adaptation of tepary germplasm accessions to high temperature is attributed to their ability to regulate stomatal opening and photosynthetic efficiency, together with a superior ability to remobilize photosynthates from older leaves to pods during physiological maturity
Field performance of heat tolerant mutant rice lines generated from Oryza sativa and Oryza glaberrima
Authors: Kusolwa Paul Mbogo , Neema Yona , Rajab Masanche , Kihupi Ashura, Luzi- , Sarsu Fatma
Published: November 2021

This study evaluated mutant lines developed from two cultivated species of upland rice, Oryza sativa, and Oryza glaberrima, in field experiments conducted during the hot and dry seasons of 2014/2015 in Morogoro, Tanzania. The growth yield and yield components of 34 and 14 Gamma induced mutant upland rice lines developed from O. sativa (Kihogo red) and O. glaberrima were evaluated, respectively. The mutant lines were selected based on variable expression of heat shock protein genes (HSPs) in previously conducted heat tolerance studies. The minimum and maximum temperatures and rainfall during the field performance experiment were measured between 20 oC and 35 oC, and 32.7 mm and 155.5 mm, respectively. The data for 12 yield and yield component parameters such as days to early and 50% flowering, days to physical maturity, plant height, number of tillers, number of panicles, spikelets, filled grains, unfilled grains and 1,000 grain weights were collected and analysed using ANOVA and Principal Component Analysis. Significant differences (P≤0.05) were obtained among the mutant lines in terms of grain yield, spikelet sterility and other variables, which were further used as criteria for selection of heat and drought tolerant rice lines. Eight heat and drought tolerant mutant rice lines with high yields (over 3.5 ton/ha) and low spikelet sterility were selected for further advancement in breeding programmes
Making New Land: An Intertidal Aesthetics
Authors: Pausz Thomas
Published: November 2021

Making New Land is an essay in theory-fiction set in a near future, where the oceans have disappeared. In these devastated landscapes, a first person narrator investigates unsolved biological enigmas on Earth and on Mars. In the footsteps of a fictional group of Anarcho-botanists called Sea for Space, the story alternates a melancholic longing for the beauty of intertidal and coastal lifeforms with futuristic visions of new species engineered by humans as new companions.
The scenario explores archetypal figures of plant-human coexistence: from the botanical gaze to a nostalgic longing for connection, and from the hubris of genetical engineering to the dream of a post-humanism communion with the vegetal. The fictional story is interwoven with scholarly references and a critical discussions of artistic and literary works dealing with the fauna, flora and mythologies of the seaside, which form the outlines of an 'Intertidal Aesthetics'.
Lettuce Entertain You: Floral Agency in Ralph Knevet's Rhodon and Iris
Authors: Howard Ashley
Published: November 2021

This essay investigates the performativity of plants in Ralph Knevet’s Rhodon and Iris, a play that was written and performed for a feast held by the Norwich Society of Florists in 1631. The play explores at least two forms of performativity: the first is the act of staging plants for a theatrical performance, where vegetables present their virtues through floral allegories that are enacted by human players. The second form is the way plants affect and are affected by their environments, particularly as theorized by Michael Marder and Mel Y. Chen. In Rhodon and Iris, these two dimensions work together to produce a form of floral agency that decenters the human. The essay explores how floral agency collaborates with literary narratives when beings perform for plants (within a history of floral celebrations), as plants (embodying plants as allegorical figures), and with plants (floral characters using plants as ingredients in cosmetics, poisons, and antidotes). Knevet uses literature to articulate a unique plant philosophy that challenges divisions between art and nature and among literature, philosophy, and science. Rhodon and Iris thus illustrates the many ways that theatrical performances and printed playbooks, and even printed herbals and herbaria, responded to and shaped the performativity of plants.