bluuebunny/crossref_metadata_2025 huggingface dataset:
Listening to Loving
Authors: Fernandes Rachel
Published: October 2022

Richard and Mildred Loving are widely recognized as revolutionaries of social change, responsible for the landmark civil rights case, Loving v. Virginia, which led to the abolition of state laws forbidding mixed-race marriage in America. The Lovings’ act of resistance is often (rightly) viewed as radical, but few scholars have focused specifically on Mildred Loving in particular as a revolutionary figure, because she was soft-spoken and reserved. This paper argues that in her quietness, Loving engaged in a deliberate form of resistance: She fought for her inalienable rights without ever raising her voice. With the assistance of Kevin Quashie’s The Sovereignty of Quiet and Tina Campt’s Listening to Images, this paper examines Mildred Loving as embodying an alternative form of Black activism. Ultimately, the paper demonstrates that Mildred Loving’s political success was a result of her commitment to quiet activism. Loving’s quiet resistance is equally—if not more—productive than larger, louder forms of resistance to white supremacy and racism in America, and this form of resistance can be translated for use in our current moment where loud acts of protest often seem like the most effective option for activism and engagement.
Paramedic’s Trust and Compliances during COVID-19 Preparedness and Recovery Time
Authors: Wasisto Aryo
Published: October 2022

High trust in government’s capability is the key to public compliance in supporting COVID-19 management. The paramedic is a profession that has received attention during times of pandemics because they are on duty as frontlines with a high risk of transmission. This research analyzed a survey of 328 paramedics living in Jakarta to examine their perceptions of the COVID-19 pandemic, the government's readiness, the picture of their psychological condition, their trust in the government, and their belief in themselves in health services. The survey was conducted one week after WHO declared COVID-19 a pandemic. This descriptive study indicates that most respondents have serious concerns about the transmission of the virus. On the side, they are obliged by an oath of service, which demands that they are always ready to serve. Only 30% believe the government can handle COVID-19. All respondents strongly supported the "lockdown" policy in every public facility. This finding is consistent with interview data after the highest peak of COVID-19 transmission in September 2021.These findings also point that low trust is driven by inconsistent and less convincing communication of political officials. Despite paramedics' risky conditions, they are responsible for working, but paramedics at the forefront of handling COVID-19 patients require support policies such as higher incentives and the safest protective tools.
Network institutionalism in women’s political interests advocacy for gender-mainstreaming of development in Lampung, Indonesia
Authors: Darmastuti Ari
Published: October 2022

Advancing women’s political interests is not an easy activity to do at least due to two factors.  First, women political representation is low both in national and local level.  Second, women’s political interests is yet acknowledged as  important subject compared to other more salient problems such as economic and political issues.  This paper aims to present a critical analysis of how women put forward their political interests in local level through local legislations.  I use mainly network institutionalism as my theoretical analytical tool. Data came from focussed group discussions (FGDs), interviews, participant observations, as well as documents from and with  women groups in executive and legislative bodies, women  non-government organizations (NGOs), women community based organizations (CBOs), professional groups, and academics.    I argue that despite their differences, women groups were able to set a relatively coherent political agendas in local level in Lampung, Indonesia.  This was shown by their ability to control sub-group identifications and develop a common identity with their slogan “united women will never be defeated” to work together for the success of their political interest advocacy.  It was also shown by their ability to develop mutual obligations and reciprocities for the success of the advocacy of the new Lampung Province Regulation on Gender-mainstreaming of Development.
TAGLN2 promotes papillary thyroid carcinoma invasion via the Rap1/PI3K/AKT axis
Authors: Wang Lidong , Tan Hao , Huang Yonglian , Guo Mingyue , Dong Yanxu , Liu Chenxi , Zhao Huai , Liu Zhen
Published: October 2022

TAGLN2, an actin-binding protein, functions as a binding protein to actin to facilitate the formation of intracellular cytoskeleton structures. TAGLN2 overexpression in papillary thyroid carcinoma (PTC) is reported in our previous study. This study aimed to examine the functions and molecular mechanisms of TAGLN2 in PTC. The clinical data analysis showed that TAGLN2 expression was associated with cervical lymph node metastasis in PTC. Gain- and loss-of-function approaches, as well as various cellular function, gene expression profiles, quantitative proteomics, and molecular biology experiments, were further exploited to explore the roles of TAGLN2 in PTC. The results showed that TAGLN2 overexpression significantly promoted the invasion of PTC cell lines (K1, TPC-1, and BCPAP). Besides, the results also indicated that TAGLN2 was associated with regulating proliferation, migration, angiogenesis, and adhesion of PTC cells. Gene expression profile, quantitative proteomics, and Western blotting were performed to identify the relevant pathways and key downstream molecules, and Rap1/PI3K/AKT signalling pathway, ITGB5, LAMC2, CRKL, vimentin, N-cadherin, and E-cadherin were finally focused on. Moreover, rescue experiments validated the involvement of the Rap1/PI3K/AKT signalling pathway in the TAGLN2-mediated invasion of PTC cells. Therefore, TAGLN2 may promote the invasion of PTC cells via the Rap1/PI3K/AKT signalling pathway and may be served as a potential therapeutic target for PTC. Developing antagonists targeting TAGLN2 may be a potentially effective therapeutic strategy for PTC.
Caracterización de Modelos Educativos de Universidades Chilenas: Configuración de sus Dimensiones Fundacionales
Authors: Núñez-Valdés Karen , Herrera-Núñez Yudi , Carvajal Cristiá , González-Campos José Alejandro
Published: October 2022

La demanda social por la reestructuración de la formación de profesionales para la sociedad del conocimiento impulsa la actualización de los Modelos Educativos (ME) de las Instituciones de Educación Superior (IES), cuya diversidad impide obtener una visión panorámica de las tendencias en Chile. En Chile las universidades estatales han experimentado políticas públicas como la del 80 que han promovido prácticas liberales en Educación Superior y la reducción del compromiso del Estado con ellas. Este estudio caracteriza los ME de las universidades tradicionales chilenas, identificando sus dimensiones fundacionales y su configuración. Se realiza un análisis de contenido con un nivel de profundización descriptivo e inferencial, mediante la revisión de una muestra representativa a nivel nacional de 15 ME de universidades tradicionales. Entre los resultados está la determinación de cinco dimensiones como un mapa de factores determinantes para la comprensión de cómo se aprende, se gestiona el currículum y qué recursos priorizan las IES. Si bien existen diferencias a nivel descriptivo entre universidades públicas y privadas, a nivel inferencial se constata su homogeneidad. En tanto que, se encuentran diferencias significativas según el año de aprobación de los modelos, evidenciando en los más recientes (después de 2016), un marcado énfasis por implementar dispositivos de rendición de cuentas, en desmedro de su vinculación territorial.
Comprensión Ontológica Indígena-Aimara de los Fines Educativos y Mito de la Escuela
Authors: Bermejo Saúl , Maquera Yanet Amanda
Published: October 2022

La diversidad de concepciones indígenas para entender al ser humano, de elaborar conocimiento y educar, históricamente negadas e invisibilizadas, requieren por justicia social ser reconocidas como fuentes para enriquecer y construir sistemas educativos auténticos. Es un estudio cualitativo-hermenéutico, cuyo objetivo es aproximarse a la comprensión ontológica de los sentidos otorgados por indígenas-aimara a los fines de la educación y el mito de la escuela. Participaron líderes indígenas residentes en comunidades del extremo Sur peruano, que mediante entrevistas en profundidad posibilitaron el registro de datos en lengua aimara. Según los resultados obtenidos a través del análisis de contenido y lingüístico-semántico, para los aimara no hay forma de distinguir la relación sujeto-objeto, todos son sujetos como experiencia colectiva de vida en armonía; perciben que la educación desmerece el núcleo ontológico del ser, supeditando a propósitos ajenos, forzándoseles a asimilarse en seres para otro, reduciéndose la teleología de la educación al éxito-fracaso escolar y la esperanza del bienestar-progreso a futuro, que además de resultar contrarios a la episteme aimara, son equivalentes según ellos a la idea de postergar la vida mientras se permanece en la escuela, constituyéndose el mito de escuela en la posibilidad de lo mismo: perpetuar la condición de ser-negado.
Descolonizar la Escuela: Educación por la Justicia en Comunidades Originarias del sureste de México
Authors: Martínez Martínez Miguel Angel
Published: October 2022

Los objetivos de las políticas educativas del actual gobierno mexicano a través de la Nueva Escuela Mexicana (NEM) proponen una educación democrática, equitativa, integral, inclusiva e intercultural, la desigualdad estructural del país se mantiene. Las políticas educativas, fuertemente vinculada a las relaciones de raza, clase social y género favorece la reproducción de una estrategia educativa conservadora que coloca a las comunidades originarias en una relación epistémica colonial, favoreciendo los prejuicios, sesgos y estereotipos hegemónicos que afectan el ejercicio de los derechos humanos fundamentales. A partir de la convivencia con estudiantes de la Universidad de la Tierra-CIDECI en el marco de la estancia en el Centro Internacional para la Innovación Social (CIIS) del Tecnológico de Monterrey, de las palabras compartidas entre los estudiantes y de la investigación sobre la práctica educativa zapatista y la teoría descolonial, se plantea un análisis político-educativo crítico que sitúa el modelo de la Universidad de la Tierra-CIDECI como una alternativa frente a la exclusión, estandarización, explotación e infravaloración hacia las comunidades originarias y sus modos de vida en el actual capitalismo neoliberal. El proyecto de la Universidad de la Tierra-CIDECI constituye un proceso descolonial de autonomía, equidad de género, defensa de los territorios y autogestión.
Formación de Docentes para la Justicia Social desde la Indagación Biográfica
Authors: Ceballos López Noelia , Saiz Linares Ángela
Published: October 2022

Nos encontramos en un escenario social y educativo caracterizado por las desigualdades que precisa un compromiso con la equidad y la justicia social. Presentamos una propuesta formativa para la justicia social que se cimenta en el desarrollo de un proceso indagatorio colaborativo sobre las situaciones de discriminación presentes en la biografía escolar de las futuras maestras. El estudio es cualitativo e involucra a dos profesoras universitarias y a 65 alumnas del grado de Educación Infantil, en el marco de una asignatura obligatoria del plan de estudios. Para el proceso de indagación, se han desplegado diferentes estrategias como son: la elaboración de Viñetas, Ketso, observaciones participantes y análisis documental de los materiales producidos por las estudiantes. Los resultados evidencian que la iniciativa ha capacitado a los futuros docentes para: identificar las situaciones de discriminación presentes en su biografía desde un posicionamiento reflexivo y crítico, reflexionando sobre su origen (discapacidad, género y origen cultural y/o económico) y su intensidad (risas, bromas, insultos o agresión). En segundo lugar, ha permitido indagar sobre los apoyos que posibilitan erradicar cualquier forma de exclusión. En conclusión, se produce un análisis del currículo y la organización encaminado hacia la lucha contra la exclusión como acción de justicia para todos.
¿Las Mujeres fueron Importantes en la Historia? Roles y Escenarios de Acción Social en las Narrativas del Alumnado de Educación Primaria
Authors: Ortega-Sánchez Delfín
Published: October 2022

Esta investigación pretende analizar las representaciones sobre los roles y escenarios de acción social de las mujeres en la historia enseñada a estudiantes de tercer curso de Educación Primaria (n = 71) de tres centros educativos de Castilla y León (España), y sus implicaciones en la formación del profesorado. Y ofrecer un modelo de evaluación interpretativo y competencial de la conciencia histórica del alumnado. Se utilizó un diseño de investigación cualitativa, que incluyó la aplicación del cuestionario de respuesta abierta, diseñado ad hoc, y el grupo focal como instrumento y técnica de recogida de datos, respectivamente. Las unidades de registro obtenidas (ni = 1.245) evidencian la continuidad y consolidación de enfoques curriculares androcéntricos en la enseñanza de la Historia desde las primeras etapas educativas. Estos enfoques se caracterizan por una concepción técnica, lineal y no inclusiva de los aprendizajes percibidos, alejada de los problemas sociales contemporáneos, de la vida social del presente y de su proyección futura. Los resultados ponen de manifiesto la necesidad de comprender la lógica subsidiaria que rige las estructuras y categorías patriarcales desde el desarrollo curricular, con el propósito de superar las jerarquías que han posicionado la historia de los hombres por encima de las acciones, narrativas e historias de las mujeres.
EFECTOS DE LOS DESCANSOS ACTIVOS EN LA ACTIVIDAD FÍSICA DE ESTUDIANTES DE PRIMARIA
Authors: Méndez-Giménez A. , Pallasá-Manteca M. , Cecchini J.A.
Published: October 2022

Los objetivos fueron examinar el impacto de los descansos activos (DA) en la actividad física (AF) de estudiantes de 2º de primaria durante las clases, el recreo y el horario extraescolar, y analizar posibles compensaciones durante el día. Participaron 46 escolares (28 niñas) de 7-8 años. Se realizó un diseño cuasi-experimental con medidas pretest y postest. El grupo experimental (n=22) recibió un programa diseñado por docentes y estudiantes. La AF se registró mediante acelerometría. Las ANOVAs de medidas repetidas mostraron efectos significativas en AFMV y AF muy vigorosa a favor del grupo experimental. El grupo experimental incrementó 14’17”/día de AFMV y 2’01”/día de AF muy vigorosa. En este grupo también se produjo un descenso de AFMV durante los recreos de 6’54”/sem y se redujo el tiempo de actividad sedentaria durante las clases en 73’30”/sem. Implicar al docente y alumnado en el diseño de DA puede aumentar la AF del alumnado.
PERFIL DERMATOGLÍFICO Y CUALIDADES FÍSICAS PREDOMINANTES EN ATLETAS MEXICANOS UNIVERSITARIOS: ESTUDIO EXPLORATORIO
Authors: Chapa-Guadiana D. , Ceballos-Gurrola O. , Gastélum-Cuadras G. , Pérez-García J.A. , Valadez-Lira J.A. , Ochoa-Ahmed F.
Published: October 2022

El objetivo del estudio es analizar el perfil dermatoglífico y su relación con las cualidades físicas predominantes en atletas universitarios en modalidades de pista y campo. Se presenta un diseño no experimental, de tipo trasversal y exploratorio, en una muestra de 87 (81%) estudiantes-atletas que forman parte del equipo representativo de atletismo de una universidad pública de México, con una edad promedio de 20.05 ± 2.2 años, 44 (50.6%) hombres y 43 (49.4%) mujeres. Para la medición y análisis de las potencialidades físicas innatas se utilizó la técnica de dermatoglifia dactilar. Los resultados muestran que las fórmulas digitales más relevantes son, L>W y W>L con un índice D10 (13.3). El 83% de los atletas están en la disciplina adecuada según el tipo de huella dactilar, cantidad de diseños y líneas. El estudio, proporciona un referente para futuros trabajos o para la detección y selección de talento para el atletismo.
FIABILIDAD Y VALIDEZ DE KINOVEA PARA ANALIZAR PARÁMETROS ESPACIOTEMPORALES DE LA MARCHA
Authors: Fernández-González P. , Cuesta-Gómez A. , Miangolarra-Page J.C. , Molina-Rueda F.
Published: October 2022

Los objetivos del presente estudio son evaluar la fiabililidad test-retest e inter-observador del software Kinovea® para la obtención de los principales parámetros espaciotemporales de la marcha, así como, estudiar la validez de criterio respecto a un sistema tridimensional de análisis del movimiento. Los resultados obtenidos son significativamente estadísticos (p < 0,05) en todos los parámetros estudiados. La fiabilidad test-retest muestra una correlación excelente en los parámetros de longitud de paso, longitud de zancada, tiempo de paso y tiempo de zancada (CCI > 0,90), y buena en la velocidad (CCI = 0,76-0,90). La fiabilidad inter-observador es excelente (CCI > 0,90) en todos los parámetros espaciotemporales estudiados en ambos observadores. La validez de criterio entre Kinovea® y VICON Motion System® es excelente para los parámetros estudiados (r > 0,80) en ambos evaluadores. Estos hallazgos respaldan el empleo de Kinovea® como una herramienta accesible y de fácil manejo, con la que obtener datos objetivos de la marcha.
SITUACIÓN DE LAS PROFESIONALES DEL FITNESS: ANÁLISIS DE CASO DE LA CIUDAD DE HUESCA (ESPAÑA)
Authors: Estrada-Marcén N. , Ruiz-Huidobro A. , Casterad-Seral J. , Cid-Yagüe L.
Published: October 2022

La situación laboral de la mujer en España ha sufrido una gran evolución y a pesar de que hay estudios que indican las diferencias en las trayectorias laborares en función del género, apenas analizan el sector del Fitness. Nuestro objetivo es describir la situación laboral de la mujer en este ámbito y sus condiciones conociendo su percepción acerca de posibles desigualdades a raíz del género. Para ello se ha empleado una metodología cuantitativa de corte descriptivo, realizándose un estudio transversal basado en la aplicación de un cuestionario autoadministrado de diseño propio. Las 33 mujeres de Huesca (España) que participaron en el estudio muestran un sector joven y con formación universitaria, pero perciben mayores dificultades para ser contratadas, para promocionar, y para conciliar, que los hombres.
Spatial contextual classification based on conditional distributions belonging to elliptical and exponential families
Authors:   , Zikarienė Eglė
Published: October 2022

Erdvinis kontekstinis klasifikavimas naudojant sąlyginius eliptinių ir eksponentinių šeimų skirstinius
Clay minerals of the bottom sediments of the Azov — Black Sea basin
Authors: SHNYUKOV Ye.F. , INOZEMTSEV Yu.I. , PARISHEV O.O. , MASLAKOV M.O. , RYBAK O.M. , KRASNOZHINA Z.V.
Published: October 2022

The Azov-Black Sea basin is the eastern part of the Paratethys Ocean, surrounded by unevenaged mountain structures of the Crimea and the Caucasus, adjacent to the continental slope of the Archean Ukrainian crystalline massif, as well as the Anatolian mountain system. By their lithological and petrographic composition, geological structures influence the composition of the rocks covering the abyssal sections of the seabed and its modern surface. Deepwater drilling has passed the section of the bottom of the Black Sea and reached the layer of sediments of the Upper Neogene (Upper Sarmatian). The upper layers of the bottom of the Black and Azov Seas are mainly represented by sediments of the Quaternary period belonging to different age intervals, which is associated with repeated changes in the level of the Black Sea basin during continental glaciations. This led to a corresponding change in the level of the basin and, as a consequence, to the influx of terrigenous material (fluvial alluvium and products of destruction of bedrock) into the deep water area. In terms of their lithological and mineralogical composition, bottom sediments reflect the material composition of their sources. At present, the upper layer of seabed sediments up to 7-10 m thick is the most studied. This layer consists of three divisions from 22 thousand years to the present. In lithological terms, this is a layer of pellets enriched in hydrotroilite, a layer of sapropels and modern terrigenous silts. Their origin is closely related to sea level fluctuations and climate change. The study of the lithological composition of bottom sediments can be considered satisfactory, while the knowledge of the finest fraction is insufficient. Preliminary studies of the clay fraction, followed by the participation of the authors in this process, studied the composition and spatial distribution of clay minerals. Among them, hydromicas, montmorillonite, kaolinite, chlorite, and mixed layered formations are the most widespread.
Transcatheter Aortic Valve Replacement and Surgical Aortic Valve Replacement Outcomes in Left Ventricular Assist Device Patients with Aortic Insufficiency
Authors: Rali Aniket S , Taduru Siva S , Tran Lena E , Ranka Sagar , Schlendorf Kelly H , Barker Colin M , Shah Ashish S , Lindenfeld JoAnn , Zalawadiya Sandip K
Published: October 2022

Background: Worsening aortic insufficiency (AI) is a known sequela of prolonged continuous-flow left ventricular assist device (LVAD) support with a significant impact on patient outcomes. While medical treatment may relieve symptoms, it is unlikely to halt progression. Surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) are among non-medical interventions available to address post-LVAD AI. Limited data are available on outcomes with either SAVR or TAVR for the management of post-LVAD AI. Methods: The National Inpatient Sample data collected for hospital admissions between the years 2015 and 2018 for patients with pre-existing continuous-flow LVAD undergoing TAVR or SAVR for AI were queried. The primary outcome of interest was a composite of in-hospital mortality, stroke, transient ischaemic attack, MI, pacemaker implantation, need for open aortic valve surgery, vascular complications and cardiac tamponade. Results: Patients undergoing TAVR were more likely to receive their procedure during an elective admission (57.1 versus 30%, p=0.002), and a significantly higher prevalence of comorbidities, as assessed by the Elixhauser Comorbidity Index, was observed in the SAVR group (29 versus 18; p=0.0001). We observed a significantly higher prevalence of the primary composite outcome in patients undergoing SAVR (30%) compared with TAVR (14.3%; p=0.001). Upon multivariable analysis adjusting for the type of admission and Elixhauser Comorbidity Index, TAVR was associated with significantly lower odds of the composite outcome (odds ratio 0.243; 95% CI [0.06–0.97]; p=0.045). Conclusion: In this nationally representative cohort of LVAD patients with post-implant AI, it was observed that TAVR was associated with a lower risk of adverse short-term outcomes compared with SAVR.
Tomographic Evaluation of Mandibular Buccal Shelf in Patients with Different Vertical Growth Pattern
Authors: García-Gonzales Luis Angel , Ruiz-García de Chacón Vilma Elizabeth
Published: October 2022

The purpose of this research was the tomographic evaluation of the Mandibular Buccal Shelf (MBS) in orthodontic patients with different vertical growth pattern. An observational, descriptive, cross-sectional and retrospective study was conducted. Tomographic images of patients aged 14 to 40 years were observed and a database was formed with those that met the inclusion criteria. The sample size was 10 for each group according to vertical growth pattern (hypodivergent, normodivergent and hyperdivergent). Then four zones of frequent insertion of extralveolar mini-screws were selected in the MBS, taking as a reference the mesial and distal roots of the first and second mandibular molar. When comparing the characteristics of MBS between vertical growth patterns, between sexes and hemiarchs, no statistically significant differences were found. However, when the characteristics of MBS were compared according to the reference root, it was found that there were statistically significant differences. The vestibular area to the distal root of the second mandibular molar presented the highest values in terms of angulation, height and thickness. There are no significant differences in the bone characteristics of MBS according to vertical growth patterns, sexes or hemiarchs. Angulation, height and thickness progressively increase from the vestibular bone of the mesial root of the first mandibular molar to the distal root of the second molar.
Effect of feed on the milk protein and fat composition
Authors: Abdellaoui L. , Khelifi-Touhami N.A. , Mebkhout F. , Tarzaali D. , Yahiaoui W.I. , Hamdi T.M. , Ouchene N.
Published: October 2022

Abstract. Feed is considered the most important factor affecting the composition of cow's milk of which the quality can be evaluated, essentially, through two parameters, the fat and protein content, because of their industrial interest. This study aims to evaluate the impact of seven different rations (R1-R7) on the protein and fat content of Prim’holstein cow milk in a cattle farm in Algiers. The results showed that the dry matter (DM) content of forages and concentrate was 72.74% (62.94% - 81.49%) and 27.25% (18.51% - 37.06%), respectively. The forage unit milk (FUM) and the digestible nitrogen matter (DNM) contents of forage were 60.50% (51.37% - 72.08%) and 61.15% (46.73% - 74.63%), respectively. In concentrate, the FUM and DNM contents were 39.50% (24.85 - 51.5%) and 38.85% (25.37 - 52.39%), respectively (Table 3). The forages showed significantly higher DM, FUM and DNM contents than the concentrate (p<0.0001). The type of ration showed a highly significant effect on the quantity of milk produced per day, protein content and defatted dry matter. However, no significant influence was observed for the fat content. The highest milk production (ranging from 17.31 to 19.64 liters/day) and the highest defatted dry matter (87.03 and 87.92 g/l) were recorded in cows which received rations R2, R3, R4 and R5 (p<0.0001). The highest protein content values (32.87 and 33.20 g/l) were observed in the milk of cows that were fed with rations R2, R3 and R4. The lowest levels were observed for rations R6 (31.80 g/l) and R7 (31.22 g/l) (p<0.0001). Protein to fat content ratio ranged from 0.79 to 0.84 and fat to protein content ratio ranged from 1.19 to 1.27. Good management of the diet and feeding practices of the dairy cows allow having an adequate protein and fat content in the milk. A diet composed of forages with an adequate supplementation in concentrate leads to the optimal results. Further studies are important to evaluate the effect of the physical form of the diet on the physicochemical quality of the milk.
Assessment of the impact of the costs of building the floor profile on the technological
flexibility of four-row buildings for free-box breeding of cows
Authors: Dimova V.
Published: October 2022

Abstract. A total of 20 popular technical and technological schemes of semi-open four-row buildings for dairy cows with widths in the range 20.60-31.00 m have been analyzed. The options have been grouped according to the internal distribution of the buildings. Their technological flexibility has been determined and a preferred range of widths with a maximum has been outlined. For the individual studied options the costs for the technological profile of the floor (including the stationary equipment) have been calculated, as well as costs for the construction of the zero cycle, the bearing and enclosing constructions of the building have been excluded. For each preferred width, the material consumption of the floor profile has been assessed according to the construction indicators: consumption of concrete and steel (reinforcement - for reinforced concrete pavement and profile - for technological equipment), related to 1 m2 of built-up area and one slaughterhouse. A methodology for qualitative assessment of technological flexibility has been developed taking into account the impact of these costs. It has been established that the buildings with widths in the range of 25.20-25.40 m have the greatest technological flexibility. Buildings with widths in the ranges of 23.20-25.20 m and 25.80-28.00 m with equal flexibility also have very good indicators. According to the developed methodology, the widths with the same technological flexibility differ in the assessment of the impact of the costs for the floor profile - to greater extent for larger width ranges. The buildings with widths of 25.20 m and 25.40 m with maximum technological flexibility are practically equivalent, and the differences in estimates taking into account the impact of total costs of concrete and steel per 1 m2 built-up area of the floor at widths 23.20 m, 25.80 m and 28.00 m are 2.1-4.0%. For the same widths, the estimates, taking into account the impact of the total cost of concrete and steel for one cattle ranch, are from 6.5 to 15.9%. The developed methodology is recommended for the practice for assessing the impact of the costs of the floor profile on the technological flexibility of buildings with a large capacity for free-box breeding of cows. Of the four-row buildings, those with widths in the range of 25.20-25.40 m and width 23.20 m are recommended.
Characteristics of some chitin body parts in worker bees (Apis mellifera L.) from hygienic and non-hygienic bee colonies
Authors: Lazarov S.
Published: October 2022

Abstract. In the conducted study the level of manifestation of hygienic behavior of 25 bee colonies was tested from
the honey bee (Apis mellifera L.) in Bulgaria. During the testing the method used for killing the brood was with an
entomological pin. Based on the results two types of colonies were determined – hygienic (where 48 h after killing the
brood the percentage of cleaned cells with dead brood was over 95%) and non-hygienic (where 48 h after killing the brood
the percentage of cleaned cells with dead brood was lower than 95%). From each bee colony young non-flying worker
bees were taken and the morphometric measurements of their chitin body parts were made. In the study 18 morphological
traits were tested and 2 indexes were calculated. High degree of reliability (p≤0.001) between hygienic and non-hygienic
bee colonies was determined for 2 morphological traits - Total length of fore wing and Length of proboscis. For the traits
Length of tibia and Width of Іst tarsus of fore leg and Width and Surface of the left wax mirror of IIIrd sternit medium degree
of reliability (p≤0.01) was determined. In 3 other traits - Length of femur of fore leg, Length of IIIrd sternit and Length of IInd
part of the cubital cell of the fore wing low reliability (p≤0.05) was established. The results obtained from the present study
indicate the existence of statistically significant differences between the morphometric characteristics of worker bees from
hygienic and non-hygienic bee colonies. These traits are related to the productivity of worker bees.
Organizacja i działalność Policji Politycznej w Polsce międzywojennej
Authors:   WSPiA – Rzeszowska Szkoła Wyższa, Polska, Żurek Konrad
Published: October 2022

After regaining independence, Poland struggled with many legal problems in the internal and external spheres, which needed to be immediately settled. This task was difficult due to the situation in the country, where several political centers made efforts to implement their own concepts of ensuring the internal security of the state. In interwar Poland, several organizational changes, including changes to the political police, were made. During the period in question, it was reorganized several times and operated under different names. The aim of this article is to discuss the organizational changes that have taken place in the political police and an attempt to assess the influence of the political police on state security.
Problematyka zaskarżalności postanowienia w przedmiocie spisu inwentarza – w poszukiwaniu intencji ustawodawcy
Authors:   Uniwersytet Jagielloński, Kraków, Polska, Perka Milena
Published: October 2022

The article presents an analysis of the regulation concerning the possibility of challenging the decision on the preparation of the inventory. The procedure for the preparation of the inventory ends with the issuance of a substantive decision on the merits. Therefore, before the amendment of 2015, it was assumed, in accordance with the resolution of the Supreme Court of 23 August 2006, that Art. 518 of the Code of Civil Procedure (CCP) was applicable and the decision was subject to a suspensive appeal. Nowadays, after the change of the law in question, the provision of Art. 637 § 4 of the CCP is assumed to be directly applicable, as it states that am interlocutory appeal may be lodged against the decision on the preparation of the inventory. Pursuant to the provisions, the afore-mentioned appeal can be also lodged against a decision dismissing an application for making an inventory, a decision to reject an application for making an inventory, and a decision to discontinue the proceedings. An interlocutory appeal may also be filed against the decision to draw up a supplementary inventory. However, there is no last resort (cassation) appeal under the current law, nor was there any under the previous legal status. This follows directly from the content of Art. 519 1 § 4(3) of the CCP. However, it should be noted that the amendment of the provisions of civil procedure gave rise to a certain far-reaching doubt. The fact that the legislator deems an interlocutory appeal to be the appropriate mean of challenge in this case suggests that these decisions do not constitute decisions on the merits. On the other hand, if the legislator did not provide for a suspensive appeal as a means of recourse against decisions on issues related to the inventory, then limiting the admissibility of a last resort appeal would seem unnecessary.
Effects of myofascial reorganization associated with kinesiotherapy on chronic pain and functionality of breast cancer survivors: development of a study protocol
Authors: Cunha Natália de Souza , Sinhorim Larissa , Schleip Robert , Zomkowski Kamilla , Santos Gilmar Moraes , Sperandio Fabiana Flores
Published: October 2022

Abstract Introduction: Breast cancer is the most common type of cancer among women. Treatments can lead to complications modifying upper limbs movement patterns and generating pain and functionality loss. Kinesiotherapy and myofascial reorganization (MR) have shown positive effects reducing chronic pain and improving upper limbs function. We hypothesize that these techniques can maximize results and reduce treatment time in clinical practice. Objective: To develop a study protocol to verify whether MR associated with kinesiotherapy is more effective than isolated kinesiotherapy to treat chronic pain and upper limb dysfunction in breast cancer survivors. Methods: Participants will be divided into two groups: intervention group (myofascial reorganization + kinesiotherapy) and sham group (traditional massage + kinesiotherapy). Six treatment sessions (once a week) and three-time assessment will occur. Instruments for assessing pain and functionality will be Visual Analogue Scale, Body Pain Diagram, Disabilities of the Arm, Shoulder and Hand Questionnaire, and goniometry. Statistical analysis will be conducted based on intention-to-treat analysis. To analyze the difference of means between groups, we will use T-Student or U Mann-Whitney test. Repeated measures ANOVA will be used to check treatments effects. Significance level for all tests will be 5%. Conclusion: We believe that the developed study protocol will show that MR associated with kinesiotherapy improve chronic pain and upper limbs functionality of breast cancer survivors.
An Overview on Macrophage Targeting: A Promising Approach
Authors: Vemuri Venkata Deepthi , Kushwaha Rekharani , Gowri Gollu , Mathala Nalini , Nalla Swathi , Allam Sasikala , Lekhya Gurijala
Published: October 2022

Macrophages are immuno cells with high flexibility among hematopoietic system. Macrophages are tangled with many diseases like chronic inflammatory, atherosclerosis, autoimmune, and cancer. Macrophages play a major role in developing the inflammation and meanwhile resolving the damage occurred during these disease conditions. Therefore, the use of macrophages in targeted drug delivery appeared to be a promising approach in modifying the microenvironment of inflammatory diseases. The macrophages with cellular backpacks loaded with drugs were appeared to be the effective drug transporter to the brain inflammation. Till date, among the different carrier systems emerged among macrophage targeting: liposomes, microspheres, nanoparticles, and dendrimers were extensively studied. The physicochemical properties like components, lipophilicity, hydrophilicity, ligand presence, and concentration of these carriers may vary the efficacy and specificity of drug targeting to macrophages. The present review provides an insight into M1 and M2 macrophages characteristics, mainly discussed the role of macrophages in regulating several inflammatory diseases. This article underlines the current status and application of different carriers for targeted drug delivery to macrophages along with their efficacy and specificity. In general, the targeted drug delivery was achieved using the carrier systems by removing the intrinsic pathway and bio protection which is offered to the therapeutic molecules. Further, the review also summarizes the newer approaches for macrophage targeting with a brief overview on recent advances and future prospects.
Digital Storytelling in an Online EFL Course: Influences on Speaking, Vocabulary, and Cognitive Load
Authors: TATLI Zeynep , SAYLAN Esin , KOKOÇ Mehmet
Published: October 2022

Digital Storytelling (DS) is an alternative instructional tool for language teaching to make the relevant process more engaging through the use of technology and to facilitate effective language learning. This single case study explored the impact of DS in an online EFL lesson on speaking and vocabulary achievement in consideration to cognitive load effect. The study utilized mixed-design analysis strategies as quantitative tests (pre-and post-vocabulary test, speaking evaluation rubric, cognitive load scale) with 33 Turkish EFL learners studying at tertiary level who participated in an online English course and interviews with 21 volunteers. Quantitative findings revealed increased vocabulary achievement after DS use and improved English-speaking skills in terms of spoken grammar, vocabulary use, fluency and coherence, and pronunciation after repeated DS use in three stories, despite high level of cognitive load due to technical incompetency of the participants. In addition, the results obtained from the qualitative data match with the results of the quantitative data in terms of positive evaluations on the impact of DS for vocabulary use, error correction, sentence formation, pronunciation, and self-study. DS can also be effectively used in online EFL education by eliminating the drawbacks of students’ digital incompetency at tertiary level. The results of this study are expected to shed light on the practitioners aiming to use DS in online language learning for teaching speaking and improving vocabulary achievement.
School Principals’ Views on Classroom Inspection
Authors: GÖLCÜK Hilmi , ATİK Servet
Published: October 2022

School principals were charged with classroom supervision which had been in the supervisors’ area of responsibility by the regulations effectuated in 2014. The aim of this study was to find out the views of school principals on classroom supervision based on the amendment of regulations. The research was conducted by a qualitative design and phenomenological method was used. Study group of the research was school principals working in the districts of Battalgazi and Yeşilyurt in Malatya, Türkiye in the academic year of 2019-2020. The semi-structured interview guide, which was designed by the researchers, was used as the data collection tool after the expert opinions were obtained and corrections were made on it. 15 school principals, who were chosen by convenience sampling, were interviewed. Interviews were recorded based on the approval of participants. Code names were given to all participants as M1, M2, M3, … Qualitative data gathered from the participants during the interviews were analyzed by content analysis. First, the researcher coded the data separately. After that, both the researcher and another field member coded the data synchronically and reached a consensus. New codes were created where divergence appeared. It can be stated that school principals have positive views on being charged with classroom supervision. In fact, school principals state that they are not troubled with their supervision duty on teachers, but supervisors should also take part in the supervision process in order to make the process more effective and active.
Deletion of sphingosine kinase 2 attenuates cigarette smoke-mediated chronic obstructive pulmonary disease-like symptoms by reducing lung inflammation
Authors: Chen Yanhui , Zhang Yongrong , Rao Cheng , Huang Jieyun , Qing Qiong
Published: October 2022

Cigarette smoke (CS) is the leading cause of chronic obstructive pulmonary disease (COPD), which is characterized by chronic bronchial inflammation and emphysema. Growing evidence supports the hypothesis that dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) is critically involved in the pathogenesis of CS-mediated COPD. However, the underlying mechanism remains unclear. Here, we report that supressed CFTR expression is strongly associated with abnormal phospholipid metabolism and increased pulmonary inflammation. In a CS-exposed mouse model with COPD-like symptoms, we found that pulmonary expression of sphingosine kinase 2 (SphK2) and sphingosine-1-phosphate (S1P) secretion were significantly upregulated. Therefore, we constructed a SphK2 gene knockout (SphK2-/-) mouse. After CS exposure for six months, histological lung section staining showed disorganized alveolar structure, increased pulmonary fibrosis, and emphysema-like symptoms in wild-type (WT) mice, which were less pronounced in SphK2-/- mice. Further, SphK2 deficiency also decreased CS-induced pulmonary inflammation, which was reflected by a remarkable reduction in pulmonary infiltration of CD45+CD11b+ neutrophils subpopulation and low levels of IL-6 and IL-33 in bronchial alveolar lavage fluid. However, treatment with S1P receptor agonist suppressed CFTR expression and increased Nf-κB-p65 expression and its nuclear translocation in CS-exposed SphK2-/-mice, which also aggravated small airways fibrosis and pulmonary inflammation. In contrast, inhibition of S1P signaling with the S1P receptor analogue FTY720 rescued CFTR expression, suppressed Nf-κB-p65 expression and nuclear translocation, and alleviated pulmonary fibrosis and inflammation after CS exposure. Our results demonstrate that SphK2-mediated S1P production plays a crucial role in the pathogenesis of CS-induced COPD-like disease by impairing CFTR activity and promoting pulmonary inflammation and fibrosis.
Lissajous curves with a finite sum of prime number frequencies
Authors: Imre Ferenc Barna , László Mátyás
Published: October 2022

The Ulam spiral inspired us to calculate and present Lissajous curves where the orthogonally added functions are a finite sum of sinus and cosines functions with consecutive prime number frequencies.
INVESTIGATION OF THE PROBLEM SOLVING AND DECISION-MAKING SKILLS OF KARATE REFEREES
Authors: BEKTAŞ Nurettin , BEKTAŞ Sümeyra , ÖZTÜRK Arda
Published: October 2022

Aim: The aim of this research is to examine the problem-solving skills and decision-making levels of karate referees. Method: The research group consists of 410 (161 female and 249 male) karate referees from different classifications who worked in the Turkish Karate Federation in the 2020-2021 season. As a data collection tool, the 35-item “Problem Solving Inventory” developed by Heppner and Petersen (1982) and adapted into Turkish by Taylan (1990) and the original Mann. et al. (1998) and adapted into Turkish by Deniz (2004) "Melbourne Decision Making Scale I-II" (MKVÖ) was used. Independent Sample T-Test, One-Factor Analysis of Variance and Pearson Correlation Test were applied to the obtained data after descriptive statistical operations were performed. Results and Conclusion: As a result of the research, while there was no significant difference in the decision-making levels of karate referees according to the refereeing year (p>0.05), there was a significant difference in the decision-making levels according to gender and refereeing classification (p<0.05). When we look at the problem-solving skills of karate referees, there were significant differences in problem-solving skills according to gender, refereeing year and refereeing classification (p<0.05).
scNMT-seq v2 v1
Authors: Zhao Liyun
Published: October 2022

scNMT-seq (single cell Nucleosome, Methylome, and Transcriptome sequencing) allows the parallel study of a single cell chromatin status, methylation profile, and transcriptome. Here, we are developing and testing modifications of the scNMT-seq pipeline. The protocol is carried out in 96w plates and typically takes 4-5 days to complete. The number of pre-amplification cycles is adjusted to tackle the problem of poor recovery after BS conversion.Primers are optimized for first-strand and second-strand synthesis to solve the problem of unmapped reads and poor amplification. Both are testified as compatible with theoriginal the original scNMTseq.
Las NIIF y la terminología contable en español: ¿un proceso de convergencia?
Authors: Gonzalo Angulo José Antonio
Published: October 2022

Las traducciones al español de las Normas Internacionales de Información Financiera (NIIF), realizadas y publicadas por la Fundación IFRS, están disponibles desde los años 90 del siglo pasado. A pesar de que las traducciones de textos contables desde el inglés a otros idiomas pueden ser complicadas, el procesoseguido en la traducción ha tratado de buscar una terminología y unas expresiones que resulten comprensibles para la veintena de países implicados. No ha sido fácil. La labor conjunta del coordinador de la traducción, de un equipo especializado de traductores y de un Comité de Revisión de las traducciones ha logrado que los profesionales contables de los países hispanohablantes, desde México a Chile, incluyendo a España y a Guinea Ecuatorial, utilicen un lenguaje cada día más común para elaborar los estados financieros bajo NIIF (o NIIF para PYMES), o bien bajo normas locales inspiradas en ellas. Las traducciones también han sido alentadas por organismos intergubernamentales como el Banco Mundial o el Fondo Monetario Internacional. Este acercamiento, que implica una pérdida relativa de soberanía para los gobiernos de los países y sus organizaciones profesionales, debe considerarse modélico por la cantidad de países implicados, por los efectos que tiene en la inversión transfronteriza y por su potencial de cara a la integración regional entre dichos países.
Evolución de la Contabilidad Ambiental en el último cuarto de siglo
Authors: Fronti-de García Luisa , Suarez-Kimura Elsa Beatriz
Published: October 2022

En este trabajo se abordan algunos de los hitos más significativos en el desarrollo de la Contabilidad Ambiental, a partir de 1997, cuando se firmó el Protocolo de Kioto, hasta nuestros días. En dicho proceso ha ido ganando autonomía este campo de la disciplina, fruto del ejercicio continuo de reflexión y retroalimentación a partir de las experiencias sobre la necesidad de reflejar las consecuencias ambientales de la gestión en el patrimonio de los entes, tanto empresariales como sin fines de lucro. El camino recorrido en el último cuarto de siglo incluye variables cuantitativas y cualitativas, intereses sectoriales y generales, evaluación de resultados e impacto de reglamentaciones generadas en torno al medioambiente. De esta forma, el involucramiento de la profesión y de académicos contables ha sido cada vez más significativo para el desarrollo de la Contabilidad Ambiental.