bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN KEBIASAAN MENGGOSOK GIGI DAN MENGKONSUMSI MAKANAN KARIOGENIK BERHUBUNGAN DENGAN KEJADIAN KARIES GIGI
Authors: Tumiwa Imelda , Ponamon Jolie Febri , Bangkut Margaretha , Mongdong Jetty
Published: October 2024

Karies gigi adalah penyakit jaringan gigi yang menyebabkan timbulnya kerusakan jaringan. Karies gigi dapat terjadi karna kebiasaan menggosok gigi yang salah dan kebiasaan mengkonsumsi makanan kariogenik yang berlebihan. Tujuan penelitian ini adalah di ketahuinya hubungan kebiasaan menggosok gigi dan mengkonsumsi makanan kariogenik dengan kejadian karies gigi. dilaksanakan di SD Gmim Ratahan, dari bulan Februari sampai Mei 2022. Jenis penelitian Kuantitatif dengan desain penelitian menggunakan pendekatan Cross Sectional. Total sampel 120 responden dari total populasi 171 anak dengan pengambilan sampel menggunakan purpossive sampling. Hasil penelitian didapati 75,8% anak yang memiliki kebiasaan menggosok gigi dengan kategori cukup, 98,3% anak yang kebiasaan mengkonsumsi makanan kariogenik dengan kategori cukup dan 95,8% anak yang memiliki karies gigi dengan kategori ada. Penelitian ini menggunakan Uji Statistic Spearman Rho dengan hasil uji secara signifikan pada variabel kebiasaan menggosok gigi dan karies gigi p-value = 0.001 < α = 0.05 sehingga Ha₁ diterima dan variabel menggkonsumsi makanan kariogenik dan karies gigi p-value = 0.001 < α = 0.05 sehingga Ha₂ diterima. Kesimpulan dari penelitian ini yaitu terdapat hubungan kebiasaan menggosok gigi dan mengkonsumsi makanan kariogenik dengan kejadian karies gigi.
HUBUNGAN PENGETAHUAN DAN SIKAP PERAWAT DENGAN TINDAKAN PEMASANGAN INFUS SESUAI SOP
Authors: Paat Febrianti , Akay Tinny , Killing Maykel , Mandagi Autry
Published: October 2024

Latar Belakang: Di rumah sakit, pengetahuan dan sikap merupakan faktor yang dapat mempengaruhi tindakan pemasangan infus sehingga dapat menimbulkan kesalahan dalam bekerja pada perawat, dan dapat membahayakan kesehatan dan keselamatan bagi pasien tersebut.Tujuan Penelitian: Untuk menganalisis hubungan pengetahuan dan sikap perawat dengan tindakan pemasangan infus sesuai SOP di ruang rawat inap di RSU GMIM Bethesda Tomohon. Metode: Jenis penelitian yaitu kuantitif dengan rancangan penelitian  menggunakan pendekatan cross-sectional menggunakan kuisisoner. Populasi berjumlah 65 responden dengan sampel berjumlah  65 responden .teknik pengambilan sampel menggunakan total sampling. Variabel independent dalam penelitian ini yaitu pengetahuan dan sikap perawat dan variabel dependent tindakan pemasangan infus sesuai SOP. Data hasil penelitian dianalisis secara univariat dan bivariat dengan menggunakan uji Chi-square. Hasil: menunjukan bahwa nilai signifikasi 0,023 ˂ α=0,05artinya terdapat hubunganantara pengetahuan perawat dengan tindakan pemasangan infus sesuai SOP. Hasil penelitian yang menunjukan bahwa terdapat hubungan yang bermakna antara sikap perawat dengan tindakan pemasangan infus sesuai SOP menunjukan nilai signifikasi 0,023 ˂ 0,05 artinya terdapat hubungan antara sikap perawat dengan tindakan pemasangan infus sesuai SOP.Kesimpulan: Kesimpulan penelitian ini yaitu Pengetahuan dan Sikap merupakan faktor yang berhubungan dengan Tindakan pemasangan infus sesuai SOP di RSU GMIM Bethesda Tomohon.
PENGALAMAN PERAWAT ICU DALAM MERAWAT PASIEN MENJELANG AJAL : STUDI FENOMENOLOGI
Authors: Reyaan Anggela , Suba Baithesda , Antoni Wenda , Rondonuwu Peeki
Published: October 2024

Pasien yang sakit kritis dan kematian adalah umum terjadi di ruang perawatan       intensif, Perawat memainkan peran yang penting dalam merawat pasien dan keluarga dalam segala fase kehidupan sejak diagnosa ditegakkan hingga menjelang ajal bahkan setelah kematian. Perawat lebih banyak menghabiskan waktunya merawat pasien menjelang ajal tujuan yang  buat  dalam penelitian fenomenologis yang ada mengenai pengalaman perawat ICU dalam merawat pasien menjelang ajal dengan mengeksplorasi pengalaman hidup perawat dan hasil penelitian kualitatif lebih menekankan makna dari pada generalisasi Partisipan dalam penelitian ini adalah perawat yang bekerja diruangan ICU dengan melakukan observasi dan wawancara langsung dilokasi penelitian Tematic Analisis Menentukan Kategorisasi Setelah pengumpulan fakta sejenis dilakukan oleh peneliti, lantas diapakan kumpulan fakta sejenis tersebut hasil dari wawancara semi-tertruktur pada partisipan proses mencari dan menyusun secara sistematis data yang diperoleh dari hasil wawancara, catatan lapangan dan dokumentasi, dengan cara mengorganisasikan data ke dalam kategori, menjabarkan ke dalam unit-unit, melakukan sintesa, menyusun ke dalam pola , perubahan sosial yang positif dapat dipromosikan dengan mendidik dan mendorong program transportasi untuk menciptakan strategi koping dan proses formal untuk membantu menangani pengaruh kematian pasien yang mungkin terjadi pada perawat ICU. terdapat tiga tema menonjol Tema 1:dukungan spritual Tema 2:sikap berempati tema 3:berkolaborasi mengambil keputusan.
Next-Generation Cyber Resilience Frameworks: Enhancing Security, Recovery, and Continuity in Modern Networked Systems
Authors:   Wichita State University, USA, Akinsanya Michael
Published: October 2024

In response to the escalating complexity of cyber threats in today’s interconnected digital environments, this study presents a next-generation cyber resilience framework that goes beyond traditional defense-focused cybersecurity measures. While conventional approaches emphasize prevention, they often fall short in providing robust mechanisms for rapid recovery and sustained operational continuity post-incident. This research addresses these gaps by developing a comprehensive, adaptive framework that integrates advanced artificial intelligence (AI)-driven threat detection, automated recovery protocols, continuous monitoring, and self-healing capabilities. Employing a mixed-methods methodology, this study rigorously evaluates the framework through simulations of critical cyber threats, including ransomware, distributed denial-of-service (DDoS) attacks, and zero-day vulnerabilities, to assess its resilience under real-world conditions. Findings demonstrate substantial advancements over existing models, with significant reductions in recovery time, minimized system downtime, and enhanced threat detection accuracy. The proposed framework’s capacity to sustain critical operations amidst attacks underscores its value for high-stakes sectors such as healthcare, finance, and infrastructure. This research contributes to the evolving field of cyber resilience by establishing a new paradigm that not only fortifies defense but also ensures swift and reliable system recovery, reinforcing the need for adaptive, automated solutions in modern cybersecurity strategy.
Enhancing resilience in various business sectors with ChatGPT and generative artificial intelligence
Authors: Patil Dimple , Rane Nitin Liladhar , Rane Jayesh
Published: October 2024

Generative artificial intelligence models like ChatGPT are improving business resilience by improving adaptability, problem-solving, and operational efficiency across sectors. In an era of rapid technological advancement and unexpected disruptions like global pandemics and economic shifts, generative AI is essential for stability and growth. By using adaptive learning, predictive analytics, and customer engagement, ChatGPT and other AI models support resilience strategies. These AI tools help businesses anticipate issues, streamline decision-making, and strengthen supply chains by processing real-time data. ChatGPT boosts customer service quality and speed, helping companies provide excellent service even during crises. By identifying vulnerabilities and proposing proactive solutions, generative AI helps businesses mitigate risks before they occur. The chapter discusses AI's role in workforce transformation, hyper-personalized customer interactions, and AI-driven scenario planning. This study examines recent developments to show how generative AI fosters business resilience and how organizations can strategically implement AI solutions to improve their adaptability and future-proof operations.
O PAPEL DA ESCOLA DE CONTAS E GESTÃO DO TCE-RJ NA PROMOÇÃO DE CULTURAS INCLUSIVAS NA GESTÃO MUNICIPAL
Authors: Nazareth Paula Alexandra , Melo Sandra Cordeiro de
Published: October 2024

O artigo contextualiza o processo de descentralização política e fiscal no Brasil, cujo marco fundamental é a Constituição Federal de 1988, por meio do qual os municípios brasileiros se tornaram os principais agentes promotores das políticas públicas, em especial as ligadas às áreas sociais. Discute sobre a crescente participação social no desenvolvimento das políticas públicas e afirma que esta se alinha aos ideais de inclusão, como um processo que reitera princípios democráticos de participação social plena. Neste sentido, a inclusão não se resume a uma ou algumas áreas da vida humana, como saúde, lazer e educação. Refere-se, portanto, a todos os esforços no sentido de garantia da participação máxima de qualquer cidadão em qualquer arena da sociedade (SANTOS, 2003). O trabalho busca definir o papel das escolas de governo como o contexto no qual se insere a Escola de Contas e Gestão do Tribunal de Contas do Estado do Rio de Janeiro (ECG/TCE-RJ) e apresenta suas atividades de formação e capacitação. Escolhe, dentre estas, o Projeto TCE-Escola Itinerante: uma parceria com os municípios do Rio de Janeiro, voltado para a capacitação de servidores dos municípios do interior, como objeto de estudo para uma ampliação do Projeto Incluir, conjunto de ações de acessibilidade para servidores com deficiência, já desenvolvido pela ECG. A ampliação sugerida pretende uma visão mais complexa da inclusão, que não se limite ao universo das deficiências, mas contemple um âmbito maior da educação, por meio da inserção dos princípios da inclusão na formação dos docentes da ECG, servidores do TCE-RJ. O objetivo engloba sensibilizá-los para os aspectos relacionados às culturas, políticas e práticas de inclusão na Administração Pública para, em seguida, com eles, realizar a revisão dos conteúdos programáticos dos cursos oferecidos no Projeto TCE-Escola Itinerante e, por fim, reformular o próprio projeto, trazendo para a centralidade de suas ações o cidadão e as políticas inclusivas.
ASSESSOR DE GABINETE DO CONSELHEIRO JOSÉ GOMES GRACIOSA, DO TCE-RJ MESTRE E DOUTOR EM POLÍTICAS PÚBLICAS, ESTRATÉGIAS E DESENVOLVIMENTO PELO INSTITUTO DE ECONOMIA DA UFRJ GRADUADO EM JORNALISMO PELA ESCOLA DE COMUNICAÇÕES E ARTES DA USP
Authors: Oliveira Luiz Felipe Vancini de
Published: October 2024

Este trabalho visa a discutir as difi culdades na análise dos processos de pensão cujo requerimento foi formulado por pessoa que afi rma ter mantido união estável com o(a) falecido(a) servidor(a) ou segurado(a), tendo em vista a informalidade de que é dotada a relação de companheirismo, a fragilidade das provas que instruem os autos e os artifícios muitas vezes usados por pessoas que não detêm tal status e buscam obter vantagens à custa do erário.
SOBRE A LEGITIMIDADE ATIVA NOS PROCESSOS DE CONSULTA PERANTE O TRIBUNAL DE CONTAS DO ESTADO DO RIO DE JANEIRO
Authors: Maia Marcelo Verdini
Published: October 2024

Este artigo trata da legitimidade ativa na propositura de processo de consultas perante o Tribunal de Contas do Estado do Rio de Janeiro. Na medida em que cada vez mais o papel preventivo e pedagógico é atribuído aos tribunais de contas, discute-se, no caso concreto, se o titular de entidades da Administração Indireta possui competência nestes processos, diante da recente alteração legislativa que retira expressamente sua competência.
INDICADORES DE DESEMPENHO, UMA FERRAMENTA DA GESTÃO PÚBLICA
Authors: Sá José Carlos Jannini de
Published: October 2024

O presente artigo pretende analisar a importância do uso de indicadores de desempenho para monitoramento das ações do gestor público, possibilitando a elaboração de diagnóstico na orientação da decisão, na implementação de indicadores no processo e na avaliação do resultado e do impacto das ações, buscando a gestão pública eficiente e comprometida com os resultados. Este estudo procura mostrar também a importância dos indicadores no acompanhamento das leis que regem o ciclo orçamentário (PPA, LDO, LOA), o monitoramento do Plano Plurianual (PPA), que é um plano de médio prazo que visa ordenar as ações do governo que levem ao atingimento dos objetivos e metas fixadas, na Lei de Diretrizes Orçamentárias (LDO), tem como parâmetro o PPA, estabelecendo as metas e diretrizes para elaboração da Lei Orçamentária Anual (LOA), verificando a execução dos programas públicos em benefício da sociedade.
DEMOCRATIZAÇÃO DA INFORMAÇÃO PARA O FORTALECIMENTO DO CONTROLE SOCIAL NA ADMINISTRAÇÃO PÚBLICA
Authors: Moreira Liliana Ribeiro Nunes
Published: October 2024

O presente artigo trata, de forma abrangente, da temática da informação, da democratização, da transparência e do controle social, apresentando a noção de cidadania como forma de geração da necessária conscientização política e os mecanismos de controle social da gestão pública. Versa sobre a era do conhecimento, na qual as tecnologias de informação e comunicação têm papel crucial no modo como o Estado cumpre suas principais funções, abordando o conceito emergente e em evolução de governo eletrônico e apresentando o conceito de accountability e a necessidade de maior transparência na relação sociedade-governo. O estudo pretende angariar diferentes tipos de informações que permitam caminhar pelo tema, possibilitando o incremento do debate já existente, a criação de novos pontos de discussão e, se possível, auxiliando na minimização de arestas sem encerrar o assunto, e sim instigando a busca de alternativas para responder as questões divergentes.
A INTELIGÊNCIA APLICADA AO CONTROLE EXTERNO
Authors: Carvalho Sérgio Lino da Silva
Published: October 2024

O presente ensaio aborda os aspectos mais importantes e mais críticos para a implantação bemsucedida da atividade de inteligência na atividade finalística do Tribunal de Contas do Estado do Rio de Janeiro (TCE-RJ), bem como seus principais benefícios para a instituição e a sociedade. O emprego de mecanismos de inteligência e o uso de técnicas de Business Intelligence (BI) como ferramenta de apoio à fiscalização, notadamente às atividades de controle externo da administração pública, têm se mostrado muito eficazes no suporte ao exercício da missão constitucional das Cortes de Contas brasileiras. O artigo busca, de forma propositiva, descrever os principais aspectos da implantação dessa importante atividade no TCE-RJ, os benefícios esperados e os principais obstáculos a serem enfrentados no processo de implantação. Para tal, se baseia em pesquisa bibliográfica e pesquisa documental realizadas naquela Corte de Contas com o objetivo de buscar na literatura e nos documentos analisados possíveis fatores relevantes a serem considerados quando da elaboração do projeto de implantação da atividade de inteligência e, ainda, em sugestões dos autores pesquisados nesse sentido. Utilizaram-se ainda técnicas de pesquisa-ação. Verificou-se que o uso de inteligência na atividade de controle pode levar a uma maior eficiência e eficácia da atuação do TCE-RJ e a uma melhoria da imagem institucional e da interação da Corte de Contas com o cidadão, numa perspectiva republicana.
ESTRATÉGIAS DAS ENTIDADES DE FISCALIZAÇÃO SUPERIOR E A AGENDA 2030 PARA O DESENVOLVIMENTO SUSTENTÁVEL
Authors: Oliveira Rita de Cássia Cerreia Guedes de
Published: October 2024

O presente trabalho apresenta as estratégias adotadas pelas instituições de fiscalização superior em prol da governança e do desenvolvimento sustentável com base na atuação dos tribunais de contas brasileiros. Aborda a interface destas estratégias com o Programa Agenda Ambiental na Administração Pública, o Plano Nacional de Produção e Consumo Sustentáveis e os Objetivos do Desenvolvimento Sustentável, uma agenda acordada entre países de todo mundo. Descreve a participação do governo brasileiro neste processo através de políticas públicas que promovem a proteção das florestas, bem como a adaptação e mitigação das alterações climáticas, com ênfase nas comunidades mais vulneráveis. Por fim, demonstra alguns dos trabalhos desenvolvidos por tribunais de contas no Brasil que abordam estes temas.
O VETOR DESENVOLVIMENTISTA DO INSTRUMENTO LICITATÓRIO
Authors: Silva Adriana da Rosa
Published: October 2024

Esta pesquisa tem como objetivo identificar, à luz do referencial teórico, os princípios e instrumentos inerentes à função regulatória dentro do processo licitatório do setor público, utilizando-o sob a forma de ações afirmativas para o desenvolvimento de regiões degradadas ou em desvantagem socioeconômica, diante da situação de dependência de algumas municipalidades com os recursos dos outros entes da federação.
1ères Journées Nationales d’Infectiologie du Bénin
Authors: ReBéMI
Published: October 2024

La résistance aux antimicrobiens est un problème de santé publique avec un impact considérable en milieu hospitalier. Cette étude visait à déterminer l'écologie bactérienne et les gènes de résistance présents dans deux hôpitaux du Bénin. Au total, 146 échantillons environnementaux et de cathéters ont été collectés au Centre Hospitalier Universitaire d'Abomey-Calavi/So-Ava et à l'Hôpital des Armées Béninoises de Cotonou. Ils ont été ensemencés sur géloses Mannitol-Salt et Eosine-Bleu de Méthylène. Les colonies obtenues ont été identifiées et leur sensibilité aux antibiotiques testée par la technique de Kirby-Bauer. Quatre gènes de résistance codant pour la production de bêta-lactamases à spectre étendu (blaCTX-M1, blaCTX-M2, blaCTX-M9, blaCTX-M15) et le gène codant pour la résistance à la méticilline (mecA) ont été criblés. Au total, 69 (53,49%) et 60 (46,51%) souches appartenant à la famille des entérobactéries et des staphylocoques ont été identifiées, respectivement. Une prédominance de Staphylococcus aureus (25,6 %) suivie d'Enterobacter cloacae (21,0 %) et de Staphylocoque à coagulase négative (21,0 %) a été observée. Ces souches bactériennes présentaient une multirésistance, notamment aux bêta-lactamines, aux fluoroquinolones, aux aminoglycosides et aux macrolides. blaCTX-M15 (42,8%) a été le gène bêta-lactamase la plus prédominante dans le génome des entérobactéries. Chez les staphylocoques, la fréquence de mecA était de 50%. Ces résultats montrent l'ampleur de la résistance aux antimicrobiens dans les hôpitaux étudiés. Ils peuvent aider à un plaidoyer pour une action urgente au niveau national notamment en ce qui concerne la gestion et l'utilisation responsable et efficace des antimicrobiens au Bénin.
SÉROPRÉVALENCE DES VIRUS HERPÈS SIMPLEX TYPE 1 ET 2 DANS UNE SÉRIE DE PATIENTS ADRESSÉS POUR L’INDICATION DE SÉROLOGIE DES VIRUS HERPÈS SIMPLEX TYPE 1 ET 2
Authors: ReBéMI  , MBOUYAP PR  , NGONO L  , MONAMELE CG  , MANGA J  , EPOTE A  , BELINGA S  , NJOUOM R
Published: October 2024

Introduction : Les Virus herpès simplex (HSV) de type 1 et 2 entraînent des infections récidivantes touchant la peau, des muqueuses et les organes génitaux. Les infections sévères sont fréquentes chez le nouveau-né et l’immunodéprimé. L’objectif de l’étude était de déterminer la séroprévalence des HSV de type 1 et 2 chez les patients adressés au Centre Pasteur du Cameroun (CPC) pour indication de sérologie HSV.
Méthodes : Nous avons mené une étude transversale sur les données de patients enregistrés dans le Système Informatique de Laboratoire (SIL) du CPC pour lesquels une indication de sérologie HSV avait été posée. Étaient inclus les patients ayant effectué une sérologie IgG anti-HSV 1 et HSV 2 de 2017 à 2022. Toutes les analyses ont été effectuées à l'aide du logiciel SPSS (Statistical Package for Social Sciences), version 22. Le seuil de significativité était p<0.05.
Résultats : Au total 3457 dossiers ont été enregistrés. Parmi eux (n=3137 ; 93,8%) et (n=1775 ;52,8 %) avaient une sérologie IgG anti SV1 et HSV 2 positive respectivement. Une co-infection était retrouvée dans 50,0% des cas. On notait pour le HSV1 (n=1516 ; 93,5%) des femmes et (n=1621 ; 94,2%) d’hommes séropositifs pendant que pour le HSV2, il y avait (n=1016 ; 58,9%) des femmes et (n=762 ; 47,0%) d’hommes séropositifs (P<0.001). La tranche d’âge de [30 -39] ans était la plus représentée (n=1057 ; 30,7%). La séroprévalence du HSV-1 et du HSV-2 augmentait avec l’âge et on notait une association significative entre la séropositivité du HSV-2 et le sexe féminin (OR[IC] :1,6[1,4-1,8], p=<0.001).
Conclusion : Séroprévalence était élevée chez les patients ayant une indication de sérologie HSV. Il serait utile de faire une étude en population pour déterminer l’ampleur du problème au sein de la population camerounaise.
Research on International Trade Development Path of Small and Medium-sized Enterprises in the Context of E-commerce Trade
Authors:   Department of Foreign Languages, Xinzhou Normal University, Xinzhou 034000, China, Lv Linlin
Published: October 2024

With the rapid development of Internet technology and the advancement of globalization, e-commerce has become an important part of international trade activities. In this context, how to expand the international market and enhance the competitiveness of small and medium-sized enterprises with the help of e-commerce trading platform has become a hot issue in current research. This paper first summarizes the development of e-commerce trade and its impact on the international trade of small and medium-sized enterprises (SMEs), and then analyzes the current situation and main problems of the international trade of small and medium-sized enterprises. On this basis, it puts forward the development path and strategy of SMEs' international trade under the background of e-commerce trade, including establishing e-commerce trade platform, strengthening supply chain management, utilizing cross-border e-commerce, strengthening brand building, and innovating service mode. This paper aims to provide theoretical support and practical guidance for SMEs to carry out international trade under the background of e-commerce trade.
Pathogenesis, Replication, Advance Genetic Variants and Major Organ Effects of COVID-19 Infection. A Literature Review
Authors:   College of Pharmacy, Lyallpur Institute of Advance Stu[Abdul Qader E-mail address: Pharmacistqader316@gmail.com ]dies (LIAS), Faisalabad Pakistan, Fatima Noor , Usman Laiba ,   Department of Pharmaceutical Chemistry Government College University Faisalabad Pakistan/ Primary and Secondary Health Care Department Government of Punjab Pakistan, Rafique Sadia ,   Department of Pharmacy, The University of Faisalabad, Faisalabad Pakistan
Published: October 2024

The COVID-19 (corona virus disease-19) infection has been spread in whole and become a global threat effecting every nation throughout the world. The COVID-19 virus has a complex spike like structure and also exhibits a complex replication process. It can effect different organs of body such as brain, kidneys, lungs, eyes and also induce psychological effects in patients which may lead to serious complications even death. With the passage of time it's genetic makeup is also changing and the new COVID-19 strains are more resistant because of unique flexibility in it’s genetic makeup. A number of genetic variants have been identified by researchers to date but no specific treatment has been available against any variant. The aim of our study is to explore the pathogenicity, replication process, major organ effects and different genetic strains of COVID-19 virus that has been identified by researchers currently.
Effect of Probiotic Lactobacillus Casei on Secretory Immunoglobulin A (S-IgA) Levels in Rats Norvegicus Strain Wistar Post Ovariectomy
Authors:   Institute of Science and Health Technology, Dr. Soepraoen Hospital, Department of Midwifery, Malang, East Java, Indonesia, Safitri Rani , Rayani Aksohini Wijayantia Tut ,   Dr Soepraoen Hospital Obstetrics and Gynecology Department, Malang, East Java, Indonesia, Alim Zainal ,   Dr Soepraoen Hospital Obstetrics and Gynecology Department, Malang, East Java, Indonesia
Published: October 2024

Estrogen promotes the growth of Lactobacillus colonies in the vagina, converting glycogen in superficial cells into lactic acid, resulting in a low vaginal pH that inhibits pathogenic bacteria. Post-menopause, Lactobacillus growth declines, leading to thinner secretions, higher vaginal pH, and a weakened immune system. This study investigates the effect of Lactobacillus casei extract on secretory immunoglobulin A (IgA) levels, vaginal acidity, and beneficial bacteria in the vaginal mucosa. An experimental post-test-only control group design was employed with 24 female rats aged 8-10 weeks, weighing 180-220 grams. Following ovariectomy and a 14-day acclimation, the rats were divided into four groups: a control group (K) with no treatment and three treatment groups (P1, P2, P3) receiving Lactobacillus casei extract at doses of 2ml, 2.25ml, and 2.5ml, respectively, administered orally for 14 days. On day 15, vaginal acidity was measured using a swab method, and IgA levels were assessed via ELISA; gram-positive staining was performed for bacterial identification. One-way ANOVA revealed that Lactobacillus casei extract significantly increased IgA levels and reduced vaginal acidity (p = 0.003 and p = 0.000). The reduction in acidity is attributed to Lactobacillus converting glycogen into lactic acid, maintaining vaginal acidity, while S-IgA on the mucosal surface acts as an opsonin and antigen-presenting cell to inhibit pathogenic growth. The study concludes that Lactobacillus casei extract can elevate secretory IgA levels and normalize vaginal pH.
Adolescents Perceptions of Factors Causing Anxiety
Authors:   Department of Midwifery, STIKes Kendedes, Malang, Indonesia, Alivia Hildayanti Rezha , Agnesia Jati Pratiwi Nanda ,   Department of Midwifery, STIKes Kendedes, Malang, Indonesia, Arik Herliawati Putu ,   Departement of Midwifery, Politeknik Kesehatan Kartini Bali, Indonesia
Published: October 2024

Adolescence is a transition period from childhood to adulthood, most of them will experience various changes. Changes that occur in adolescents can be physical, mental and social changes. Some factors that cause anxiety that have been studied include fear of change, thinking too much about something, not having friends to talk to, and many more. The purpose of this study is to determine the factors that cause anxiety based on their experiences. The exploratory qualitative research method was used in this study to reveal the experiences of adolescents who have excessive anxiety. The results of the study showed that adolescents have various perceptions about the factors that cause anxiety in themselves, including; 1) Loss, 2) Thinking too much about something, 3) Broken family, 4) Verbal bullying, 5) Trauma, 6) Failure to do something, 7) Economic problems in the family and 8) Too sensitive.
Explore Innovation and Practice of Collaborative Training Mode for Vocational Education Teachers Based on Modern Industrial College
Authors: Xiong Xinghua
Published: October 2024

The contemporary vocational education landscape is rapidly evolving, necessitating an innovative approach in the preparation of vocational education teachers. Central to this transformation is the integration of collaborative practices within training modalities to meet the changing demands of modern industries. This study presents an innovative collaborative training mode for vocational education teachers, pioneered by the Modern Industrial College framework. Investigating the proficiency requirements of teachers within the context of contemporary industrial advancements, this model emphasizes an amalgamation of industry-academia collaboration, multidisciplinary teaching competencies, and a curriculum responsive to technological innovation. Through a methodical examination that qualitative analyses, this research validates the effectiveness of the proposed training mode in enhancing teacher readiness and adaptability to industrial evolutions. The study concludes with a comprehensive set of recommendations tailored to policy-makers, educational institutions, and industries that aspire to uplift the standards of vocational education. These guidelines are poised to facilitate a robust platform for vocational teacher training that aligns closely with the needs of the modern workforce and the imperatives of industrial growth.
Pengaruh Tingkat Pengetahuan Ibu Hamil dengan Tanda Bahaya Kehamilan di Praktik Bidan Bersama Bina Ibunda 2023
Authors: Renanti Malia , Hidayat Reni , Sofia Lina
Published: October 2024

Warning Signs of Pregnancy are symptoms that can indicate danger during pregnancy, which, if undetected, may lead to the death of both mother and fetus. Therefore, it is essential for pregnant women to recognize these warning signs so they can immediately seek help from the nearest healthcare facility if they experience any of them. The purpose of this study is to assess the level of knowledge among pregnant women regarding pregnancy warning signs at the Bina Ibunda Midwife Joint Practice in 2023. The variables studied include the level of knowledge about various pregnancy warning signs, including those related to preeclampsia, bleeding, premature rupture of membranes, hyperemesis gravidarum, and other warning signs. The research design used is a descriptive study. The population consists of pregnant women at the Bina Ibunda Midwife Joint Practice in 2023, with a sample size of 100 pregnant women. Sampling was conducted in September 2022 using Consecutive Sampling techniques. The results show that most of the pregnant women 84% have a good level of knowledge about pregnancy warning signs, while 16% have a moderate level of knowledge. Specifically, 67% of the women are well-informed about preeclampsia warning signs, 76% have good knowledge of bleeding warning signs, 86% are well aware of premature rupture of membranes, 59% understand the warning signs of hyperemesis gravidarum, and 67% are well-versed in recognizing other warning signs. The conclusion from this study is that the majority of pregnant women have a good level of knowledge about the warning signs of pregnancy.
Focus on Adoption: Changes, Evolution and Areas of Tension
Authors: Chateauneuf Doris , Piché Anne-Marie , Lavallée Carmen
Published: October 2024

Research framework:
Adoption has existed for many years as an institution that promotes
family ties, taking forms that vary based on place, culture and time

.

However, the ways in which the social actors involved use adoption
reveal specific conceptions of the child, the family, affiliations and family
relationships.

Objectives:
This issue aims to identify the evolution of certain social and
legislative adoption practices and to discuss the family and identity realities
associated with adoption, in order to provide an analysis of how it has changed over
time.

Methodology:
The articles in this issue highlight the many aspects of adoption: not
only does it affect a number of different actors (adopters, adoptees and parents of
origin), but it also raises concerns and questions of a social, legal and family
nature.

Results:
Adoption is a subject of study at the intersection of several
disciplines, including law, anthropology, sociology, psychology and social work. The
various cases discussed in this issue also illustrate the importance of reflecting on
the implications of adoption for individuals, families and society as a whole.

Conclusions:
The cases cited in these articles illustrate the need to approach
adoption from a dynamic perspective that takes into account the evolution, contexts and
changes involved in all the issues associated with it.

Contribution:
This issue is intended to stimulate reflection, both now and in the
future.
L’adoption simple : une institution française au
potentiel insuffisamment exploité
Authors: Kessler Guillaume
Published: October 2024

Cadre de la recherche : L’aspiration des
minorités sexuelles à accéder à une parenté dont elles étaient autrefois exclues, le recul
de l’âge moyen de la première grossesse et le phénomène multifactoriel de diminution du
nombre d’enfants adoptables montrent qu’il est nécessaire de penser l’adoption autrement,
en acceptant qu’elle ne soit pas forcément exclusive du maintien des liens avec les
parents d’origine.

Objectifs : Cet article vise à
identifier quels ajustements pourraient être réalisés afin de permettre à l’adoption
simple de développer tout son potentiel dans le contexte sociétal contemporain.

Méthodologie : L’étude a été effectuée en s’appuyant
essentiellement sur une analyse de la législation et de la jurisprudence française et des
éclairages théoriques, tout en laissant une place au droit comparé (Canada, États-Unis et
Cuba).

Résultats : Il apparaît que, malgré le besoin
évident de reconnaissance accrue des filiations électives dans un contexte de déconnexion
de la biologie et de la parenté, l’idée de reconnaître une véritable pluriparenté reste
difficile à accepter pour le législateur français, et que l’adoption simple est
dévalorisée en tant que source secondaire de filiation.

Conclusions : Il suffirait, pour libérer le potentiel de l’adoption simple, de
procéder à de simples ajustements : équivalence des droits en matière d’autorité parentale
ou de fiscalité successorale, utilisation dans le contexte de la protection de l’enfance
et extension à toutes les situations de pluriparenté, dès lors qu’il est de l’intérêt de
l’enfant de se voir reconnaître un parent additif.

Contribution : Cet article montre que la difficulté persistante du législateur
français à tirer les conséquences des évolutions sociétales récentes qu’il a pourtant
accompagnées est essentiellement liée à la ténacité du mythe de l’engendrement et que des
évolutions majeures pourraient être réalisées sans grand effort, dans l’intérêt des
enfants.
Seul.es au monde ? Les jeunes adultes et la
solitude pendant la pandémie
Authors: Van de Velde Cécile , Boudreault Stéphanie , Berniard Laureleï
Published: October 2024

Cadre de la recherche : Les jeunes adultes ont
constitué le groupe d’âge ayant le plus souffert du sentiment de solitude pendant la
pandémie. À ce jour, ce phénomène a principalement été approché par des indicateurs
standardisés en santé mentale : nous défendons l’idée qu’une perspective sociologique peut
apporter un éclairage différent sur ces expériences.

Objectifs : Cet article adopte une approche centrée sur les parcours de vie pour
examiner les diverses significations de la solitude pendant la pandémie, ainsi que les
conditions sociales de son émergence. Nous explorons les principales sources de solitude
chez les jeunes, les émotions qui y sont liées et les stratégies adoptées pour y faire
face.

Méthodologie : Notre enquête s’appuie sur
l’analyse comparée de 48 récits de vie conduits en 2020 et 2021 auprès d’individus âgés de
18 à 30 ans, issus de milieux sociaux variés, à Montréal (16), en Gaspésie (16) et à
Toronto (16).

Résultats : Tous les récits sont
initialement marqués par l’existence d’un « choc de solitude », mais ils se polarisent
fortement en trois grandes expériences différenciées : la solitude comme « gouffre »,
comme « combat » ou comme « ressource ».

Conclusions :
On ne peut réduire la solitude pandémique des jeunes à la souffrance de l’isolement : dans
notre enquête, les jeunes adultes ont été touché.es par
différents types de solitude — relationnelle certes, mais aussi existentielle et politique
— marquantes pour leur génération. Nous montrons également comment la précarité tend à
créer un processus de « cumul des solitudes » et soulignons le rôle paradoxal des médias
sociaux sur ces différents types de solitude.

Contribution : Cet article offre une meilleure compréhension des facteurs sociaux et
générationnels à l’origine de la hausse marquée de la solitude des jeunes pendant la
pandémie. Il permet de mieux saisir la dynamique des inégalités sociales dans ces
expériences.
Les services écosystémiques dans les programmes, les manuels et les ressources en ligne de SVT : une simple rationalisation positiviste du rapport de l’Homme à la Nature ?
Authors: Barroca-Paccard Marco , Turcotte Sandrine
Published: October 2024

Les nouveaux programmes de Sciences de la Vie et de la Terre (SVT) en Première générale incluent une section sur les services écosystémiques. L’objectif principal est de passer d’une approche anthropocentrée à une approche écocentrée, intégrant la notion de services écosystémiques (SE). Notre article propose une analyse épistémologique du concept de SE, examinant la définition, la diversité des exemples et services, le rôle de l’Homme dans l’environnement, la monétarisation et les liens avec l’éthique environnementale. L’analyse a été réalisée en utilisant un corpus constitué des programmes de SVT, des manuels scolaires et de ressources en ligne, mettant en évidence une diversité d’exemples et de documents abordant les SE. La discussion aborde la prise en charge de l’incertitude et de la complexité pour dépasser une rationalisation positiviste du rapport de l’Homme à la Nature.
Les éco-délégués ou comment éduquer le citoyen en milieu scolaire ?
Authors: Chauvigné Céline
Published: October 2024

Le contexte du dérèglement climatique et les réactions juvéniles qu’il suscite ne sont pas sans interroger les pouvoirs publics et en particulier l’éducation nationale. Récemment réactivée, au sein des programmes, la question du développement durable s’inscrit à tous les échelons du parcours des élèves par l’intermédiaire des éco-délégués, dernière initiative (2019) généralisée pour une éducation à la responsabilité vis-à-vis de la préservation de la planète. Notre propos vise à questionner les enjeux, les objectifs et les finalités d’une telle éducation du futur citoyen entre conditionnement, émancipation et responsabilisation.
Rapport à la réforme de la formation initiale des enseignants en INSPÉ : des formateurs sous tension(s) ?
Authors: Françoise Christine , Perez-Roux Thérèse
Published: October 2024

L’article s’intéresse aux tensions éprouvées par les formateurs et formatrices d’enseignant.e.s oeuvrant au sein des Instituts nationaux supérieurs du professorat et de l’éducation, suite à la mise en oeuvre de la réforme de la formation initiale (rentrée 2021). Ainsi, le positionnement des concours en fin de master a abouti à une nouvelle organisation des contenus de formation. Une enquête par questionnaire (n = 725) a été réalisée au printemps 2022. Après avoir défini la place et le rôle des formateur.trice.s dans la professionnalisation des futurs enseignant.e.s, les analyses ont permis la mise en exergue de tensions présentes dans le discours des enquêté.e.s. Cette dernière réforme, entre continuités et ruptures, a engendré des tensions aux sources multiples et a contraint nombre de formateur.trice.s à reconsidérer leur activité, jugeant quelques-unes des mesures prescrites comme paradoxales. Les dilemmes qui en résultent ont ainsi poussé ces formateur.trice.s à réviser leurs priorités, à réajuster leurs pratiques, à requestionner leur professionnalité et le sens de leur travail.
DETERMINANTS OF INCOME INEQUALITY IN THE SELECTED GROUP OF EUROPEAN COUNTRIES: A PANEL DATA ANALYSIS
Authors: Boršič Darja , Matej Podgoršek Simon
Published: October 2024

The paper focuses on providing basic characteristics of income inequality in a group of selected European countries in the period from 2000 to 2019. After presenting stylized facts and brief literature review, the paper proceeds to empirical analysis of income inequality in the observed countries by panel data techniques. Fixed and random effects models are estimated. After Hausman test approved the usage of fixed effects model, it was tested for serial correlation and robust standard errors were calculated. The empirical analysis of the determinants of income inequality shows that GDP growth, share of population in upper 10% of income percentile, Human Development Index and unemployment rate increase income inequality measured by Gini index, while share of workforce and share of population with tertiary education decrease income inequality. The results of the empirical analysis provide insight into determinants of income inequality, which may be useful for economic policy decision makers in their efforts to decrease the income inequality.
TOURISM DEVELOPMENT IN THE REPUBLIC OF NORTH MACEDONIA IN THE PERIOD 1991-2021
Authors: Risteski Michael , Nestoroska Ivanka
Published: October 2024

The Republic of North Macedonian tourism development in the past 3 decades is characterized by oscillations caused as a result of different external and internal socio-economic and political conditions. Although the tourism development recorded a continuous increase in the analysed time frame, the whole period was characterized by constant challenges, limitations and threats while at the same time the competition got higher. In this context, the purpose of the paper is to present the main characteristics of tourism development in the The Republic of North Macedonia for the period 1991-2021.This research was designed according to defined tourism indicators with the aim to determine the causes and consequences of changes in tourism development. This will allow defining future strategic courses of action for increasing the level of the country’s tourism competitiveness. For this purpose, quantitative, qualitative and comparative approaches were applied in order to draw appropriate conclusions The research findings show that tourism in the analysed period played a rather small role in the country’s employment, investments and exports, while its share in the overall economic development is presented by an average of only 2,1% in the GDP. Hence, tourism is still not being recognized as an important driver of the country’s economic development. The gained research results are a good basis for conducting similar analyses related to Macedonia's opportunities for tourism development. The obtained findings will contribute to the widening of knowledge about the characteristics of tourism development in The Republic of North Macedonia.
THE COVID-19 CRISIS IMPACT ON THE BUSINESS OF COMPANIES IN BOSNIA AND HERZEGOVINA
Authors: Marjanović Jelena
Published: October 2024

The research in this paper aims to examine the types and usefulness of the measures implemented by Bosnian companies to protect themselves from the COVID-19 crisis. All business entities, especially small businesses, faced hardships in performing operational activities and severe financial problems during the crisis. Their managers reacted differently to the consequences of the pandemic outbreak. A survey was conducted among Bosnian companies for research purposes, and its results indicated that defensive and innovative strategies were used equally to maintain business activity. The support of state institutions at all levels played an important role in cushioning the negative impact. Nevertheless, the innovative activities of the company, accompanied by the business digitization were even more significant.
Morphodynamic Cartography Visualization of Wulan River Estuary Systems from Space to Numerical Approach Based on Multi-Season Analysis
Authors: Khakhim Nurul , Kurniawan Agung , Pranowo Widodo Setiyo
Published: October 2024

This research aims to investigate the morphodynamics of the Wulan River estuary in Demak Regency using the integration of multispectral remote sensing images and numerical modeling. In this study, PlanetScope for a manualvisual analysis of estuary morphodynamics and Sentinel-2 MSI Level 2A to obtain periodic total suspended solids (TSS) information for the east and west monsoon seasons. MIKE by DHI software used to develop hydrodynamic numerical modeling in order to characterize the current circulation and sediment transport model. Based on a marine cartography aspect, the obtained results illustrated that the climatological phenomenon of seasonal forcing plays a role in the development of the current circulation and indirectly influences the sediment transport. During the west season, the morphodynamics in the Wulan River estuary are much more massive and significant as compared to the east season. A projection of the deposition that results from the sediment transport is described in the bed-thickness change; this occurs in the western part of the Wulan River estuary during the east season, while the bed-thickness change occurs predominantly in the northern part during the west season (where there was previously a beach sandbar phenomenon). This was verified through multi-temporal satellite imagery that the deposition that occurs in the northern part of the Wulan River estuary during the west season is increasingly progressive and massive.
PKCδ is an activator of neuronal mitochondrial metabolism that mediates the spacing effect on memory consolidation
Authors: Comyn Typhaine , Preat Thomas , Pavlowsky Alice , Plaçais Pierre-Yves
Published: October 2024

Relevance-based selectivity and high energy cost are two distinct features of long-term memory (LTM) formation that warrant its default inhibition. Spaced repetition of learning is a highly conserved cognitive mechanism that can lift this inhibition. Here, we questioned how the spacing effect integrates experience selection and energy efficiency at the cellular and molecular levels. We showed in Drosophila that spaced training triggers LTM formation by extending over several hours an increased mitochondrial metabolic activity in neurons of the associative memory center, the mushroom bodies (MBs). We found that this effect is mediated by PKCδ, a member of the so-called ‘novel PKC’ family of enzymes, which uncovers the critical function of PKCδ in neurons as a regulator of mitochondrial metabolism for LTM. Additionally, PKCδ activation and translocation to mitochondria result from LTM-specific dopamine signaling on MB neurons. By bridging experience-dependent neuronal circuit activity with metabolic modulation of memory-encoding neurons, PKCδ signaling binds the cognitive and metabolic constraints underlying LTM formation into a unified gating mechanism.
Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover
Authors: Kim Seung Mi , Quagraine Yaw , Singh Monika , Kim Jung Hwan
Published: October 2024

Dual leucine zipper kinase (DLK) mediates multiple neuronal stress responses, and its expression levels are constantly suppressed to prevent excessive stress signaling. We found that Wallenda (Wnd), the Drosophila ortholog of DLK, is highly enriched in the axon terminals of Drosophila sensory neurons in vivo and that this subcellular localization is necessary for Highwire-mediated Wnd protein turnover under normal conditions. Our structure-function analysis found that Wnd palmitoylation is essential for its axon terminal localization. Palmitoylation-defective Wnd accumulated in neuronal cell bodies, exhibited dramatically increased protein expression levels, and triggered excessive neuronal stress responses. Defective intracellular transport is implicated in neurodegenerative conditions. Comprehensive dominant-negative Rab protein screening identified Rab11 as an essential factor for Wnd localization in axon terminals. Consequently, Rab11 loss-of-function increased the protein levels of Wnd and induced neuronal stress responses. Inhibiting Wnd activity significantly ameliorated neuronal loss and c-Jun N-terminal kinase signaling triggered by Rab11 loss-of-function. Taken together, these suggest that DLK proteins are constantly transported to axon terminals for protein turnover and a failure of such transport can lead to neuronal loss. Our study demonstrates how subcellular protein localization is coupled to protein turnover for neuronal stress signaling.