bluuebunny/crossref_metadata_2025 huggingface dataset:
Responses of ground-dwelling arthropods to long-term prescribed fire regimes in a savanna protected area.
Authors: Mukwevho Ludzula , Ndlovu Mduduzi , Chikowore Gerald , Dalu Tatenda , Mutamiswa Reyard , Chidawanyika Frank
Published: September 2022

Background
Sound management of protected areas is crucial for biodiversity conservation. In savanna systems, fire is common, yet little is known on the direct and long-term effects of prescribed burns on arthropod abundance, richness, and diversity. Standardised pitfall traps and active searches were used to compare variation in abundance, richness and diversity of arthropods at various experimental burn plots in the Kruger National Park, a protected area in a savanna setting.
Results
Hymenopterans: Formicidae were the most abundant (76.4%), whilst Coleopterans, Araneae and Orthopterans constituted 18.6, 3 and 1% of the total arthropods collected respectively. Coleopterans were the most diverse group (30.2%) compared to Hymenopterans: Formicidae (24.6), Araneae (24.6) and Orthopterans (4%). Abundance, species richness and diversity of multi-taxa significantly differed between the treatment plots. Abundance and diversity of Formicidae were significantly lower, hence, species richness was significantly higher in annually burnt plots compared to the unburnt control plots. Although the highest number of arthropods was recorded in unburnt plots, species richness and diversity were lowest in these plots compared to those burnt annually and triennially.
Conclusions
We conclude that late summer burns do not have major ecological impact on arthropods, and it was demonstrated by the abundance and diversity of species recorded at the annually burnt plots. Thus, annual late summer burns can be used as a conservation tool for arthropod inhabiting the protected savanna of Kruger National Park.
Study of dam-break flow over a vegetated channel with and without a drop
Authors: Khoshkonesh Alireza , Sadeghi Seyed Hossein , Gohari Saeed , Karimpour Somaye , Oodi Shahin , Francesco Silvia Di
Published: September 2022

The development of catastrophic floods triggered by a dam failure is influenced by the river's bed nonuniformity, infrastructure, and vegetation in the main channel or floodplain. This study examined the effects of the presence of a drop and its direction in a vegetated channel on flow characteristics during dam failure. A CFD package was used for all dam break flow simulations. Using experimental data from the literature, a sensitivity analysis of the fluid cell size and turbulence models were performed. Then, the model was used to predict the flow characteristics during a dam break over the vegetated channel with positive, negative, and no drops. The results showed that the model reproduced with high accuracy the evolution of the flow during a dam break in the presence of an obstacle and transitions, as well as variations in flow velocity. The presence of a drop, its height and direction, and vegetation significantly changed the reservoir discharge, hydrograph in the downstream channel, flow velocity values, location of the inflection points, density, and eddy evolution.
Effect of different custom-made mouthguard palatal extensions on the stress-state of dentoalveolar: a 3D-FEA
Authors: Sun Zhe , Zhang Jiayun , Sun Ruitong , Zhang Meng , Zhong Qingqiu , Huang Minghao , Yan Xu , Li Jian
Published: September 2022

Objectives
The present study aimed to simulate the influence of the palatal extension of a custom-made mouthguard (MG) on protecting dentoalveolar structures and to provide a theoretical basis for designing a comfortable MG.
Materials and Methods
Based on the finite element analysis (3D-FEA) method, five groups of maxillary dentoalveolar models of wearing MG were established —no MG on the palatal side (NP), on the palatal gingival margin (G0), 2 mm from the palatal gingival margin (G2), 4 mm from the palatal gingival margin (G4), 6mm from the palatal gingival margin (G6) and 8mm from the palatal gingival margin (G8). A cuboid was created to simulate the ground, a gradually increasing force was applied from 0N to 500N on the vertical ground and the distribution and peak values conditions of the Critical modified von-Mises stress, maximum principal stress and displacement of dentoalveolar models were calculated.
Results
The stress distribution range, stress and deformation peak value of dentoalveolar models increased as the impact strength increased, at 500N, but the position of the MG palatal edge had little effect on the stress distribution, stress and deformation peak value of the dentoalveolar models.
Conclusions
The different extension ranges of the MG palatal edge have little effect on the protective ability of the MG on maxillary teeth and maxilla. An appropriate palatal extension of MG is the key to improving their wearing comfort, which may help dentists to design a suitable MG and increase its usage.
Clinical Relevance
Optimized MGs' palatal design to provide a comfortable MG for those involved in sports and increase the usage of the MGs.
Fluoride concentration in saliva after toothbrushing with power or manual toothbrush and Sodium Fluoride-containing toothpaste, a clinical crossover study
Authors: Bottenberg Peter , De Bruyne Anneveere , Verhelle Heleen , Jacquet Wolfgang
Published: September 2022

Background

Power toothbrushes gain increasing acceptance for oral hygiene procedures. However, the brush head is generally smaller than that of a manual brush thus accommodating less toothpaste. This might influence salivary fluoride concentrations.

Methods

In a group of 20 adult volunteers in a 2-legged crossover study. They were instructed to use their habitual quantity of toothpaste (containing 1450ppm as NaF) ad libitum on a manual or power toothbrush. Salivary samples were taken at baseline, after 2 minutes brushing, after 5 minutes and then stepwise up to 60 minutes after brushing. Salivary samples were electrochemically analyzed for fluoride (ISE) for TF (total fluoride, whole sample after acid digestion) and IF (ionizable fluoride after centrifugation but without digestion), Area under the curve (AUC) and curve parameters after regression were calculated and compared using nonparametric statistical methods.

Results

Toothpaste quantity was significantly (p < 0.05) higher with manual toothbrushes (manual ranging from 0.3-2.1g, electric from 0.2-1.2g). Volunteers placing low amounts of toothpaste on a manual brush also did so on the power brush (Spearman-rank correlation coefficient 0.503, p = 0.024). However, this difference in quantity was not reflected in AUC in saliva (p > 0.05). A small but significant difference was found between TF and IF for AUC, reflecting some interaction between saliva compounds and fluoride, independent of toothbrush type.

Conclusions

Interindividual variability is more important in fluoride availability in saliva than differences in toothpaste quantity between power and manual toothbrushing.
Trial registration: Belgian health authorities n° B670201836852
Trial registration: Belgian health authorities n° B670201836852
Fangchinoline derivatives inhibits PI3K signaling in vivo and in vitro in non-small cell lung cancer
Authors: Chen Jia-shu , Guo Xu , Wang Mu-xuan , Gao Xiu-zheng , Han Jin-long , Sun Jin-yue , Li Ning-yang , Simal-Gandara Jesus , Liu Chao
Published: September 2022

Background
Cancer is a primary public health problem worldwide today. Tetrandrine (Tet) and fangchinoline (Fan) are extracted from the traditional Chinese medicine Stephania tetrandra S., which are two types of bis-benzyl isoquinoline alkaloids with anti-tumor activity. However, Tet and Fan are not suitable for clinical application due to their high effective doses.
Results
Through chemical modification, 19 novel Tet and Fan derivatives were firstly proposed and synthesized in this work, and they were assessed for the cytotoxicity against six tumor cell lines (H520, H460, HepG-2, HeLa, A549, and MCF-7) and human bronchial epithelial cells (BEAS-2b) by the CCK-8 assay. Compared to the parent Fan, ten derivatives demonstrated better cytotoxic effects, and 4b exhibited the strongest inhibitory activity against A549 cells growth (IC50 = 0.78 µM) and low toxicity against BEAS-2b cells (IC50 = 17.22 µM). Encouragingly, the IC50 value of compound 4b was 0.78 µM, demonstrating 3.53-fold, 10.22-fold and 12.13-fold more anticancer activity than HCPT, Tet and Fan, respectively. Subsequently, the anti-tumor mechanism of compound 4b was studied by hoechst 33258, flow cytometry, cell scratch, western blotting, and JC-1 staining. The results indicated compound 4b remarkably inhibited the cell migration by decreasing MMP-2 and MMP-9 expression and inhibited the proliferation of A549 cells by arresting the G2/M cell cycle. Meanwhile, compound 4b could also induce A549 cell apoptosis by promoting endogenous pathways of mitochondrial regulation. Subsequently, we simulated the drug stability of compound 4b in vivo, compound 4b showed a hydrolysis half-life of over 8 h in simulated gastric and intestinal fluids. In addition, in vivo experiments in nude mice presented that the growth of tumor tissues was markedly inhibited by the consumption of compound 4b in a dose-dependent manner, and the inhibition rate of the high-dose group (40 mg/kg) was greater than 50%. Regarding the anti-tumor mechanism of compound 4b, it was found that compound 4b could inhibit the mTOR/PI3K/AKT pathway in vivo. Furthermore, the binding mode of BCl-2 and Bax with compound 4b was investigated by performing a molecular docking study.
Conclusions
In summary, our present study unveiled the antitumor activities of 19 novel derivatives against the normal lung epithelial BESA-2b cells and six cancer cell lines in vitro. Furthermore, the following experiments illuminated that compound 4b could exert antitumor effects and induce apoptosis by regulating the PI3K/Akt/mTOR signaling pathway in vivo through triggering the mitochondria-mediated intrinsic pathways. This newly Fan derivative could exert antitumor effects in vivo and in vitro, which implied that compound 4b would be a prospective new anti-lung cancer drug for future development.
Comparative Assessment of Improved SVM Method under Different Kernel Functions for Predicting Multi-scale Drought Index
Authors: Pande Chaitanya , Kushwaha N. L. , Orimoloye Israel R. , Kumar Rohitashw , Abdo Hazem Ghassan , Tolche Abebe Debele , Elbeltagi Ahmed
Published: September 2022

Precise assessment, monitoring and forecasting of drought phenomena are crucial and play a vital role in agriculture and water resources management in the semi-arid region. In this study, Standardized Precipitation Index (SPI) was used to predict the drought in the upper Godavari River basin, India. Ten combinations were used to predict three SPI timescales (i.e., SPI − 3, SPI-6, and SPI-12). The historical data of SPI from 2000 to 2019 was divided into training (75% of the data) and testing (25% of the data) models for SPI prediction. The best subset regression method and sensitivity analysis were applied to estimate the most effective input variables for estimation of SPI 3, 6, and 12. The improved support vector machine using sequential minimal optimization (SVM-SMO) with various kernel functions i.e., SMO-SVM poly kernel, SMO-SVM Normalized poly kernel, SMO-SVM PUK (Pearson Universal Kernel) and SMO-SVM RBF (radial basis function) kernel was developed to estimate the SPI. The results were compared and analyzed using statistical indicators i.e., root mean square error (RMSE), mean absolute error (MAE), relative absolute error (RAE), root relative squared error (RRSE), and correlation coefficient (r). The main results showed that the SMO-SVM poly kernel model precisely predict the SPI-3 (R2 = 0.819) and SPI-12 (R2 = 0.968) values at Paithan station; the SPI-3 (R2 = 0.736) and SPI-6 (R2 = 0.841) values at Silload station, respectively. The SMO-SVM PUK kernel showed superiority in the prediction of SPI-6 (R2 = 0.846) at Paithan station and SPI-12 (R2 = 0.975) at the Silload station. The competition between SVM-SMO poly kernel and SVM-SMO PUK kernel was observed in the prediction of long setting time (i.e. SPI-6 and SPI-12), while SVM-SMO poly kernel is superior in the estimation of SPI-3 at both stations. The results of the study showed the efficacy of the SVM-SMO algorithm with various kernel functions in the estimation of multiscale SPI and can be helpful in decision making for water resource management and tackle droughts in the semi-arid region of central India.
LINC01137 facilitate pancreatic cancer stemness via the miR-7155-5p/KLF12/AKT axis
Authors: Li Kexian , Feng Zengyu , Qin Kai , Ma Yang , Zhao Shiwei , Chen Peng , Lin Jiewei , Jiang Yongsheng , Han Lijie , Cao Yizhi , Luo Jiaxin , Shi Minmin , Chen Hao , Wang Jiancheng , Jiang Lingxi , Peng Chenghong
Published: September 2022

Background
Pancreatic cancer, of which pancreatic ductal adenocarcinoma (PDAC) is one of the most prevalent type, is one of the most malignant tumors, with a 5-year survival rate of about 10%. Pancreatic cancer stem cells play pivotal roles in chemoresistance and recurrence. Long non-coding RNAs (lncRNAs) have been identified as key regulators of the biological progression of various cancers. LncRNAs were found to be associated with cancer stem cells, which are related to chemoresistance. LINC01137 has been reported as an oncogene in oral squamous cell carcinoma, and bioinformatic analysis found it associated with pancreatic cancer stem cells. This study is aim to discover the function and the underlying mechanism of LINC01137 in pancreatic cancer.
Results
LINC01137 was pancreatic cancer stem cell-associated lincRNA and associated with stem genes. LINC01137 was upregulated in pancreatic cancer tissues and cell lines. Its high expression correlated with poor prognosis. Knockdown of LINC01137 expression reduced pancreatic cancer stemness, chemoresistance, and proliferation. Mechanistically, LINC01137 mostly located in cytoplasm and exerted its biological function by binding to miR-7155-5p to activate the KLF12/PI3K/AKT pathway. KLF12 also promoted LINC01137 expression. LINC01137 and KLF12 were involved in promoting PDAC tumorigenesis.
Conclusion
Our results suggested that LINC01137 functions as an oncogene in pancreatic cancer and identified its post-transcriptional regulatory mechanisms, which may contribute to targeted therapy for pancreatic cancer.
Path Planning of Mobile Robots Based on An Improved Particle Swarm Optimization Algorithm
Authors: Yuan Qingni , Sun Ruitong , Du Xiaoying
Published: September 2022

Aiming at disadvantages of particle swarm optimization in the path planning of mobile robots, such as low convergence accuracy and easy maturity, this paper proposes an improved particle swarm optimization algorithm based on differential evolution. First, the concept of corporate governance is introduced, adding adaptive adjustment weights and acceleration coefficients to improve the traditional particle swarm optimization and increase the algorithm convergence speed. Then, in order to improve the performance of differential evolution algorithm, the size of the mutation is controlled by adding adaptive parameters. Moreover, a "high-intensity training" mode is developed to use the improved differential evolution algorithm to intensively train the global optimal position of the particle swarm optimization, which can improve the search precision of the algorithm. Finally, the mathematical model for robot path planning is devised as a two-objective optimization with two indices, i.e., the path length and the degree of danger to optimize the path planning. The proposed algorithm is applied to different experiments for path planning simulation tests. The results demonstrate the feasibility and effectiveness of it in solving mobile robot path planning problem.
Effects of SiO 2 nanoparticles and Piriformospora indica on tomato (Lycopersicone sculentum) under water stress in aeroponic system
Authors: Akhlaghi-Mohammadi Fatemeh , Movahedi Zahra , Ghabooli Mehdi , Rostami Majid
Published: September 2022

In this research,three levels of fungi; non-inoculated, spore, and myceliuminoculated plants, and three levels of nanoSiO2;0,50 and 100 mM, were studied under non-water stress andwater stress conditions. Analysis of variance and mean comparisons indicated that application of both nanoSiO2 and P. indica had positive effects in inducing drought tolerance in tomato regarding morphological (root and shoot properties), biochemical (protein, anthocyanin, phenol), physiological (proline, chlorophyll a and b), tolerance indices (relative water content and electrolyte leakage), antioxidant enzymes (CAT, GPX and APX) traits.Comparison of two trials under water stress, showed that the mycelium form of P. indica was better than the spore form and it was better than100 mMnano SiO2 in CAT enhancing while only the spore form of fungiwas better than100 mMnano SiO2in chlorophyll-b.Under water stress, application of the 100 mMnano SiO2 could produce more root volume and dry weight than any fungi treatments. Our results indicated the positive impacts of P. indica and SiO2 nanoparticles on drought tolerance in tomato but the P. indica was more efficient than SiO2 nanoparticles in most traits, which could be related to better symbiosis of fungi with roots.
Measure the difference in efficiency in waste disposal and collection services from the EU targets in the Campania municipalities.
Authors: Ferraro Aniello , Garofalo Antonio , Marchesano katia
Published: September 2022

The study analyses the economic and environmental performance of the 353 municipalities in the region of Campania in the waste disposal and collection services. This study consists of three steps, firstly municipal performance in the management of waste services from a linear economy point view is assessed. Secondly, a circular economy paradigm is considered and jointly the economic (minimization of management costs) and environmental (waste minimization) performance of municipalities management is measured; two different DEA models are employed using information provided by the Institute for Environmental Protection and Research for the year 2016. Third, in order to rank the most virtuous municipalities in the environmental dimension (toward a circular economy paradigm), the study defines a measure of the efficiency deviation from environmental sustainability. The results show a cluster of municipalities in the metropolitan area of Naples and Caserta with a worse performance in the environmental dimension but with a good performance in the economic dimension. The succession of national and regional regulations has accentuated the uncertainty in the executive process and in the management of the waste cycle, creating a regulatory vacuum. Local governments should act on citizen motivations, promoting awareness on environmental issues, and should implement time-saving collection methods.
JEL: D61; H3; H76; I38; Q24; Q53; Q56; R14;
Optimal forest management of pure and mixed forest plantations in the southeastern United States
Authors: Moeller Jonas C. , Susaeta Andres , Deegen Peter , Sharma Ajay
Published: September 2022

Due to their high degree of heterogeneity, mixed forest plantations give rise to numerous questions regarding the economic feasibility of this type of forest management. We simulated the growth of loblolly pine mixed in various proportions with white oak and sweetgum, two commercially important hardwood species of the southeastern United States, to obtain a better understanding of the optimality of mixed plantation management. The most relevant result was that, in all scenarios, the maximum land expectation values of mixed plantations are higher than the maximum land expectation values of pure plantations established for timber production only, and for plantations managed for combined timber production and carbon sequestration. We identified the density effect between the loblolly pine trees within the mixed plantations as the main factor driving the value of mixed plantations. The mixed white oak and sweetgum trees also increased the maximum land expectation values of the mixed stands in comparison to the less dense pure loblolly pine stands. This implies that the incorporation of hardwoods adds timber but the trees do not represent a substitute for pine. Our analysis showed that mixed forest plantations can be a feasible economic option to diversify the production of timber in the region.
A PROSPECTIVE STUDY OF ACUTE FISSURE-IN-ANO IN RELATION TO CLINICAL DIAGNOSIS AND MANAGEMENT
Authors:   Sr Resident., Bharambe Pankaj , Kshirsagar Samadhan ,   Associate Professor., Phadke Nikhil ,   Professor., Kshirsagar Samadhan ,   Associate Professor.
Published: September 2022

An anal fissure is a longitudinal ulcerated area in the vertical axis of the squamous lining of the anal canal between the anal verge and the dentate line, noted in 10Ã¢Â€Â“15% of proctological patients. Present study was aimed to study, acute fissure-in-ano in relation to clinical diagnosis and management at a tertiary hospital. Present study was hospital based prospective observational study, conducted in patients between 18-70 years of age ( including males & females ), with symptoms of pain on defecation, bright red bleeding, constipation (i.e. suspected cases of acute anal-fissure). Among 100 subjects, 47 % subjects were between aged 31-40 years. mean age of study subjects was 36.44 Ã‚Â± 3.2 years. Out of 100 patients,51% were males and 49% were females. Posterior fissure in ano was present in 90% of males and anterior fissure was present in 20% females. Also concomitant fissures were present in 6% females. 75% Patients (70% male and 80% female) were pain-free after 2 weeks of medical line of management. 84% Patients (84% males and females each) were pain-free after 4 weeks of medical line of management. 91% Patients (92% males and 90% females) were pain-free after 6 weeks of medical line of management. Out of 100 patients, 4% (males and females) undergone surgery (lateral internal sphincterotomy) after 8 weeks of medical line of management and relieved of symptoms. Acute fissure-in-ano, can be treated with medical (conservative) line of management, which is effective, cheaper and feasible way of treatment. Those who are still symptomatic can undergo surgery (lateral internal sphincterotomy).
MULTILOCULAR APPEARANCE OF ORTHOKERATINIZED ODONTOGENIC CYST: A CASE REPORT
Authors:   Resident of Oral and Maxillofacial Surgery, Farwaniya Speciality Dental Center, Kuwait., Hashar Alenezi Mohammad , Tarek Karkar Khalid ,   Specialist of Oral and Maxillofacial Surgery, Farwaniya Speciality Dental Center, Kuwait.
Published: September 2022

Orthokeratinized odontogenic cyst (OOC) was initially defined as the uncommon orthokeratinized type of odontogenic keratocyst (OKC) by the World Health Organization (WHO). Several studies have shown that OOC has different clinicopathologic aspects when compared with other developmental odontogenic cysts, especially OKC. So OOC now emerges to be a distinct entity, according to the 4th edition of the WHO Classification of Head and Neck Tumors which was published in January 2017. Clinically, it usually occurs as a single cyst with a unilocular radiographic appearance in posterior mandible with a predilection in males and mostly is seen between the third and fourth decades. In this case we present an OOC arise as a multilocular lesion causes thinning and expansion of the buccal cortical plate treated by enucleation and curettage.
VASCULAR COMPLICATIONS OF SERIOUS VIPERS ENVENOMATION: ABOUT A CASE
Authors:   Vital Emergency Reception Service Arrazi Hospital - Surgical Resuscitation Service Arrazi Hospital, CHU Mohammed VI- Marrakech., Mourouth H. , Saroukh F. ,   Vital Emergency Reception Service Arrazi Hospital - Surgical Resuscitation Service Arrazi Hospital, CHU Mohammed VI- Marrakech., Meghraoui Y. ,   Vital Emergency Reception Service Arrazi Hospital - Surgical Resuscitation Service Arrazi Hospital, CHU Mohammed VI- Marrakech., Douirek F. ,   Vital Emergency Reception Service Arrazi Hospital - Surgical Resuscitation Service Arrazi Hospital, CHU Mohammed VI- Marrakech., Ziadi A. ,   Vital Emergency Reception Service Arrazi Hospital - Surgical Resuscitation Service Arrazi Hospital, CHU Mohammed VI- Marrakech.
Published: September 2022

Declared as a neglected disease by the OMS, snakebites are responsible for 421,000 cases of envenomation and 20,000 deaths worldwide. In Morocco, they are much rarer but remain serious with heavy consequences. It is exceptional to observe a mesenteric infarction following a bugloss envenomation. The physiopathological mechanism is not clearly established, but seems multifactorial. In a context of multivisceral failure, diagnosis can be difficult and therapeutic delay is life-threatening. We report the case of lower limb ischemia associated with mesenteric infarction in a 66-year-old patient complicating a horned viper bite.
HISTOLOGICAL OUTCOMES AFTER REGENERATIVE PERIODONTAL THERAPY WITH EMDOGAIN
Authors:   Private practice, Singen, Germany., Egloff Corina , Beresescu Gabriela ,   Department of Tooth and Arch Morphology George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures Romania., Monea Adriana ,   Department of Odontology and Oral Pathology George Emil Palade University of Medicine, Pharmacy, Science, and 16 Technology of Targu Mures, Romania., Ormenisan Alina ,   Department of Oral and Maxillo-Facial George Emil Palade University of Medicine, Pharmacy, Science, and 16 Technology of Targu Mures, Romania.
Published: September 2022

Objective: The aim of this study is to evaluate the histological and clinical outcomes of intrabony defects treatment using regenerative periodontal therapy with enamel matrix proteins (Emdogain, EMD). Material And Method:Ten patients with chronic periodontitis were included in this randomized, controlled clinical study. Two groups received conservative periodontal therapy. In the test group, different teeth received regenerative treatment with EMD. In the control group only conservative periodontal therapy was performed. The following parameters were recorded at baseline and after 8 months: pocket probing depth (PD) and histological examinations. Results:Both groups showed a significant reduction of PD. The teeth treated with EMD showed a significant attachment gain. Within the test group, the radiographic examination of the teeth treated with EMD showed no significant change, whereas the teeth in the control group showed significant bone reduction. Conclusion:Treatment of intrabony defects with EMD may lead to substantially higher gains in clinical attachment and defect filling. The use of EMD in dental practice can prevent further bone loss.
EMOTIONAL AND BEHAVIORAL PROBLEMS AMONG ADOLESCENTS IN JODHPUR CITY
Authors: Humane Sushil , Parihar Aashish , Mohan Remiya
Published: September 2022

Adolescents are highly vulnerable to psychiatric disorders. This study aimed to explore the emotional and behavioral problems in adolescents. A community-based exploratory survey was conducted between November and December 2019. Cluster sampling was done. 300 adolescents in12 to 18 years of age group from the different randomly related areas of Jodhpur city were involved in the study. Emotional and behavioral problems were assessed by using a self-structured Emotional and behavioral problem questionnaire. Inform consent and assent were taken before filling the questionnaire Descriptive and inferential statistics were applied for analysis. SPSS version 16 was used for data analysis.Emotional problems are more prevalent in the population. Nearly 41% of participant falls under the borderline category and 1.33% i.e. 4 participant falls under the severe category comparatively behavioral problems are less prevalent. 21.66% of participant has a borderline level of behavioral problem and only one participant was found to have a severe level of behavioral problem. The domains under emotional problems have a higher mean value than the domains under behavioral. A number of siblings are significantly associated with behavioral problems. Emotional problems are more prevalent than behavioral problems. These data suggest that there is a need for mental health services for adolescents.
EFFECTS OF MYOFASCIAL TRIGGER POINT RELEASE AND THERABAND STRENGTHENING AMONG THE COLLEGIATE VOLLEY BALL PLAYERS WITH GLENOHUMERAL IMPINGEMENT
Authors:   Research Scholar, School of Physiotherapy, Vistas., Karthikeyan S. , Nirmal Kumar B. ,   BPT 4thYear, School of Physiotherapy, Vistas., Senthilselvam P. ,   Head of the Department, School of Physiotherapy, Vistas.
Published: September 2022

Background: Volley ball is one of the common sport and most of the college students choose this as a recreational game. Almost 80% of the shoulder injuries are related to spiking movement during the game. This stress the upper arm and the shoulder leading to increased risk of injuries. The common factors that results in shoulder injuries are Glenohumeral internal rotation deficit, Glenohumeral impingement syndrome, scapular dyskinesis and altered biomechanics of ball striking movement. Aim of The Study: The present aim of the study is to identify the effectiveness of Myofascial trigger point release technique and Theraband strengthening on Glenohumeral muscles among the collegiate volley ball players with Glenohumeral impingement syndrome. Methods: There were 30 players taken for the study and pretreatment values were taken. Myofascial trigger point therapy have been applied to supraspinatus muscle. The outcome measures used for the study is Numerical pain rating scale, range of motion and shoulder pain and disability index. The post treatment values were taken. Results: The results of the present study were analyzed using pairedt test and Wilcoxon signed rank test and the test statistics shows statistically significant improvement in the posttest p value < 0.05. Conclusion: The present study concluded that Myofascial trigger point release and Theraband strengthening exercises shows significant improvement in pain reduction, improves range of motion and functional ability among the collegiate volley ball players.
CONSUMER BRAND PREFERENCES TOWARDS DECORATIVE PAINTS
Authors:   Assistant Professor Chandigarh Group of Colleges, Mohali., Sharma Bhavna , Sharma Palki ,   Associate Professor Chandigarh Group of Colleges, Mohali.
Published: September 2022

In an intensely competitive market, brand is a powerful differentiator. It enables the organisation to make strategic decisions. Brand preference is also a crucial aspect of the consumers lifespan. A strong brand increases the organizations esteem and credibility among its competitors. Businesses now have much better relationships with their distributors, suppliers, rivals, and even the government. The reputation of the company among investors is enhanced by a strong brand, which represents a higher ROI and a larger market share. Companies with strong brands attract top personnel and gain the respect of industry experts.Small businesses must build their brands in order to compete globally. Small scale products usually lack appealing features since they require powerful branding. India has made progress in the past 15 years thanks to the financial reform, growth, privatisation, and globalisation processes. International commerce and economic realms are interwoven with the labour force and the countrys economy. Cutthroat productivity has been cited as the primary force dictating how business is planned, along with Indias economic advances and globalisation. This paper tries to understand the power of brand and consumer brand preferences towards decorative paints.
KNOWLEDGE, ATTITUDES AND PRACTICE REGARDING OCULAR COMPLICATIONS DUE TO DENTAL INFECTIONS AMONG DENTAL STUDENTS IN QASSIM, SAUDI ARABIA
Authors:   Associate Professor, Department of Ophthalmology, College of Medicine, Qassim University, POB 4490, Buraidah, Saudi Arabia., A. Alzuhairy Sultan , A. Alzuhayri Sulaiman ,   Dental Intern, College of Dentistry, Qassim University, Saudi Arabia.
Published: September 2022

Objectives:The study aims to assess the knowledge, attitude and practice of dental students regarding the ocular complications that occur due to dental infection. Methods: A cross-sectional questionnaire-based survey was conducted with a questionnaire consisting of 11 questions (six knowledge items and five attitude and practice items) was distributed among first-, second-, third-, fourth- and fifth year dental students via email. Of 120 questionnaires distribution, 102 questionnaires were filled by the students, hence the response rate of this study was 85%. All the items were in the format of multiple-choice questions. Based on the responses from 102 questionnaires, the frequencies and percentages for each item of the survey were analyzed. Results:Nearly 63% of participants were aware of ocular complications resulting from dental infection. Discussion with colleagues and peers are the main source of information (56%) among the dental students. Three-fourths of the participants (75%) reported that these complications were under-reported in textbooks, curriculum and literature. More than 80% of the participants indicated that ocular complications should be considered seriously if not considered it may result in irreversible ocular damage, and 83% advocated research on ocular complications due to dental infections. Conclusion: Even though the awareness of ocular complications due to dental infections was found to be adequate among our undergraduate dental students, there is a need of education and training about prevention and initial management of these sorts of complications associated with dental infections and post tooth extraction. Moreover, this awareness and early diagnosis of ocular complications and appropriate referral to ophthalmologists will improve the patient outcomes.
FUNCTIONAL OUTCOME OF DISPLACED CLAVICLE FRACTURE TREATED BY INTRAMEDULLARY NAILING: A PROSPECTIVE STUDY
Authors:   Post Graduate Resident, Department of Orthopaedics NSCB Medical College and Hospital Jabalpur., Kothale Jayant , Turkar Rajesh ,   Associate Professor, Department of Orthopaedics NSCB Medical College and Hospital Jabalpur., Naik Sparsh ,   Assistant Professor, Department of Orthopaedics NSCB Medical College and Hospital Jabalpur., Vidyarthi Ashok ,   Head of Department, Department of Orthopaedics NSCB Medical College and Hospital Jabalpur.
Published: September 2022

Background:Clavicle fracture is one of the most common injury.Despite the high incidence, the choice of proper treatment is still controversial. This prospective study was done to evaluate functional outcome of displaced clavicle fracture treated by intramedullary nailing. Material and methods:The study was conducted on 30 patients(25 males and 5 females) with displaced/comminuted clavicle fracture treated by either elastic intramedullary nails or elastic intramedullary nails with endcap.Followupexamination for functional and radiological evaluationwas done at 1 month,3 months and 6 months. Results: Mean duration of clinical union in comminuted and transverse/oblique fracture was 6.41 weeks and 6.89 weeks respectively while the mean duration of radiological union in comminuted and transverse/oblique fracture was 8 weeks and 8.5 weeks respectively.In co-relation between functional outcome and fracture pattern we obtained P-value 0.418,0.842 and 0.453 for Constant shoulder,DASH and VAS scores respectively which was statically not significant that means there was no relation between fracture pattern and functional outcome. Conclusion:- The intramedullary fixation of displaced clavicle fracture is a safe minimally invasive technique. The intramedullary nailing holds advantages of high union rate, minimal periosteal stripping and soft tissue damage, minimal blood loss and relatively less complications. This technique provides faster return to daily and professional activities with excellent functional results. Implant removal is easier and can be done as day care procedure under local anesthesia.
A STUDY ON OCULAR CHEMICAL INJURIES WITH THEIR WISUAL OUTCOMES
Authors:   Head of Unit 1, Seth GSMC and KEM Hospital., G. Kamath Kokila , Waghmare Piyusha ,   Senior Resident, Seth GSMC and KEM Hospital.
Published: September 2022

Ocular chemical Injury comprises about 8-18% of overall ocular trauma. It is caused by various types of acids and alkalis.Alkalis penetrate deep and cause severe injury. Acid cause lesser severity of burns.It is more common in age group of 20-40 years.It is the true ocular emergency and requires immediate intervention. It can cause a greviousvisual impairment in younger economically productive age group. Hence, it is necessary to evaluate the damages caused by it with optimal intervention to restore vision. This study enables the analysis of current management of ocular chemical injury and its effect on the visual outcomes of the patients.
CASE REPORT UROTHELIAL CARCINOMA OF BLADDER WITH SARCOMATOID FEATURES AND GIANT CELL COMPONENT
Authors:   King Fahad Specialist Hospital (KFSH)., Alfulaij Abdullah , Binjabaan Bander ,   King Fahad Military Hospital., Alomair Nessrin ,   King Fahad Specialist Hospital (KFSH)., Alabandi Ali ,   Dammam Central Hospital.
Published: September 2022

Around 0.3 percent of all primary tumors of the urinary bladder are sarcomatoid carcinomas, a rare aggressive tumor with a poor prognosis. Histological diagnosis for urothelialcarcinoma plays a significant role but is challenging in several ways. Making a foundational diagnosis relies heavily on immunohistochemistry. We present a case of high-grade urothelial cancer with sarcomatoid characteristics and having components of giant cells. The case discusses an 80-year-old male who had been referred because of painless intermittent hematuria. A 32 m mass at the posterior and lateral walls of the urinary bladder without perivesical fat infiltration was detected during a computed tomography urography. Histopathology results from the transurethral resection of the patient showed pTa high-grade malignant giant urothelial carcinoma with spindle cell tumor. Due to recurrence, the patient underwent Re-TURBT twice in our institution and had a BCG re-induction intravenously. Given that it contained mesenchymal markers such as EMA, IHC corroborated the final diagnosis of sarcomatoid cancer. It is crucial to recognize the unusual variations of urinary bladder urothelial tumors because they have an impact on prognosis and general care. The diagnosis is largely determined by immunohistochemistry. For aggressive variants, radical cystectomy is the standard treatment however, intravenous BCG may be beneficial for patients who are not fit for surgery.
PERCEPTION OF SECONDARY SCHOOL TEACHERS AND STUDENTS ON RE-OPENING OF SCHOOLS DURING COVID-19 PANDEMIC SITUATION
Authors:   Assistant Professor, Department of Education, Aligarh Muslim University, Aligarh, India., Ahmed Anjum , Rukhsar Zeba ,   PGT, Redbricks International School,Kottakkal, Kerala.
Published: September 2022

Coronavirus infections are baneful and are a global concern. As on 9th January, over 304million confirmed cases of COVID-19 and over 5.4 million deaths had been reported.Because of this increase, UNESCO has spread information on school closures around theworld. This research will aid in understanding secondary school teachers and studentsperspectivesonthere-openingofschoolsintheaftermathoftheglobalCOVID-19outbreak.This research is descriptive in nature, the total sample of the study was 160 secondary school teachers and students. The result of the study shows that the teachers concerns in every dimension were more than theconcerns of students. Out of all the concerns, Social concern was at the top for teachers,andAcademicconcernwasforthestudents.Andtheleastscoreamongthefourdimensions was Emotional concern for teachers and social concern for students. Theteachers believed that they will have to deal with lots of disarray behaviour of the studentswhen they will join the school offline. To them, maybe, once the socialization concernsare taken care of, other concerns like emotional, psychological and academic concernswill automatically be taken care of.And for students at the secondary level, they aremore concerned regarding their academics and how they will cope with the academicactivities loss.
CLINICAL SIGNS COMMONLY SEEN ON ENT EXAMINATION OF SYMPTOMATIC ACTIVE COVID-19 PATIENTS IN OUR TERTIARY CARE CENTRE
Authors:   M.B.B.S., M.S. E.N.T. Senior Resident, Department of Otorhinolaryngology, MGM Medical College, Navi Mumbai, Maharashtra, India., Nagarajan Sivasubramaniam , Gosavi Swapnil ,   M.B.B.S., M.S. E.N.T., F.O Assistant Professor, Department of Otorhinolaryngology, MGM Medical College, Navi Mumbai, Maharashtra, India., Rajiv Kumar Kalpana ,   M.B.B.S., M.S. E.N.T. Professor and Head of Department, Department of Otorhinolaryngology,MGM Medical College, Navi Mumbai, Maharashtra, India., Mathur Arpit ,   M.B.B.S Junior Resident, Department of Otorhinolaryngology,MGM Medical College, Navi Mumbai, Maharashtra, India., Puthen Purayil Jubina ,   M.B.B.S., M.S. E.N.T. Assistant Professor, Department of Otorhinolaryngology,MGM Medical College, Navi Mumbai, Maharashtra, India., Patil Supriya ,   M.B.B.S., M.S. E.N.T. Associate Professor, Department of Otorhinolaryngology, MGM Medical College, Navi Mumbai, Maharashtra, India.
Published: September 2022

Objectives: The study intends to identify various clinical signs on proper ENT examination. This knowledge will help in successfully identifying infected individuals which can be otherwise missed on screening the patient. Study Design and Setting: This study is a Prospective Cross Sectional Study, a type of an Observational Analytical study. 70 individuals who were admitted in the COVID-19 wards in our Tertiary Care Hospital were subjected to fulfillment of the inclusion and exclusion criteria prepared for this study. Methods: Participants were chosen based on the selection criteria prepared for the study. After obtaining an informed consent, a proper and safe Otorhinolaryngological examination was performed with all necessary precautionary measures. Data was collected as per the designed clinical proforma. Results: 80% of the patients had the presence of clinical signs with respect to Otorhinolaryngology. 43 patients had clinical signs on Throat examination, 35 patients had clinical signs on Nasal examination while 9 patients had Ear related clinical signs. The ENT related clinical signs mostly included Nasal mucosa congestion, Posterior Pharyngeal Wall congestion and presence of Granulations in the Posterior Pharyngeal wall. Reduction of Smell and Taste was also elicited on clinical examination. Other clinical signs also included Tonsil enlargement, n/ Tympanic Membrane retractions and decreased hearing on clinical evaluation. Conclusion: Knowledge of ENT related clinical signs in COVID 19 patients are important while examining patients in the Out Patient Department or Clinic. Focus on ENT related clinical signs are also as important as symptomology.
Prediction of operation vibration state of coal mine mechatronics equipment based on data mining
Authors: Jia Faxian , Deb Nabamita , Sajja Guna Sekhar
Published: September 2022

In order to explore the prediction of the operation vibration state of coal mine mechatronics equipment, the author proposes a method based on data mining in response to the problems of large amount of data in the operating state of coal mine electromechanical equipment, low data utilization, and slow speed of single-machine massive data mining, using Map Reduce technology, a dual Map Reduce mining prediction framework is proposed, establish a data mining prediction model for the running state of dual Map Reduce, using MapReduce1 to extract features of monitoring data, use MapReduce2 to predict and analyze feature data. Finally, by building the Hadoop platform, reveal the relationship between Hadoop cluster nodes and parallel processing speed, the efficiency of the data mining prediction framework is verified: Perform an experimental comparative analysis of the single prediction model and the proposed AGB combined prediction model, the prediction accuracy of the AGB combined prediction model is verified.
A DINÂMICA TRANSVERSAL DA SEGURANÇA ALIMENTAR E NUTRICIONAL NA ARQUITETURA DO PROGRAMA NACIONAL DE ALIMENTAÇÃO ESCOLAR
Authors: Ferreira Martins Naiara , Dias Varella Marcelo
Published: September 2022

A polissemia e aplicabilidade do termo transversalidade encontram caminhos diversos no âmbito da gestão pública. A transversalidade conecta-se diretamente com a gestão do Programa Nacional de Alimentação Escolar (PNAE) que envolve a articulação dos setores escolares, da agricultura familiar, na nutrição e da saúde. A pesquisa constitui-se na reconstrução jurídica do percurso do PNAE, a partir da inserção da alimentação na agenda pública, como programa mais antigo no âmbito da tutela universal da alimentação de escolares. Ademais, aplica-se a abordagem transversal a fim de analisar o PNAE enquanto articulador da integração entre setores, fator necessário e, simultaneamente, complexo para a manutenção e aprimoramento do Programa. Por fim, busca-se conferir uma nova ótica à arquitetura institucional do PNAE com o intuito de fomentar a interação contínua de uma rede integrada.
Optimizing Outcomes in Psychotherapy for Anxiety Disorders Using Smartphone-Based and Passive Sensing Features: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Müller-Bardorff Miriam , Schulz Ava , Paersch Christina , Recher Dominique , Schlup Barbara , Seifritz Erich , Kolassa Iris Tatjana , Kowatsch Tobias , Fisher Aaron , Galatzer-Levy Isaac , Kleim Birgit
Published: September 2022

BACKGROUND

Psychotherapies, such as cognitive behavioral therapy (CBT), currently have the strongest evidence of durable symptom changes for most psychological disorders, such as anxiety disorders. Nevertheless, only about half of individuals treated with CBT benefit from it. Predictive algorithms, including digital assessments and passive sensing features, could better identify patients who would benefit from CBT, and thus, improve treatment choices.

OBJECTIVE

This study aims to establish predictive features that forecast responses to transdiagnostic CBT in anxiety disorders and to investigate key mechanisms underlying treatment responses.

METHODS

This study is a 2-armed randomized controlled clinical trial. We include patients with anxiety disorders who are randomized to either a transdiagnostic CBT group or a waitlist (referred to as WAIT). We index key features to predict responses prior to starting treatment using subjective self-report questionnaires, experimental tasks, biological samples, ecological momentary assessments, activity tracking, and smartphone-based passive sensing to derive a multimodal feature set for predictive modeling. Additional assessments take place weekly at mid- and posttreatment and at 6- and 12-month follow-ups to index anxiety and depression symptom severity. We aim to include 150 patients, randomized to CBT versus WAIT at a 3:1 ratio. The data set will be subject to full feature and important features selected by minimal redundancy and maximal relevance feature selection and then fed into machine leaning models, including eXtreme gradient boosting, pattern recognition network, and k-nearest neighbors to forecast treatment response. The performance of the developed models will be evaluated. In addition to predictive modeling, we will test specific mechanistic hypotheses (eg, association between self-efficacy, daily symptoms obtained using ecological momentary assessments, and treatment response) to elucidate mechanisms underlying treatment response.

RESULTS

The trial is now completed. It was approved by the Cantonal Ethics Committee, Zurich. The results will be disseminated through publications in scientific peer-reviewed journals and conference presentations.

CONCLUSIONS

The aim of this trial is to improve current CBT treatment by precise forecasting of treatment response and by understanding and potentially augmenting underpinning mechanisms and personalizing treatment.

CLINICALTRIAL

ClinicalTrials.gov NCT03945617; https://clinicaltrials.gov/ct2/show/results/NCT03945617

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/42547