bluuebunny/crossref_metadata_2025 huggingface dataset:
The Impact of Animal Agriculture on Human Health
Authors: Kassay Andrea
Published: May 2021

Animal agriculture contributes to many health problems that exist today, such as the spread of infectious diseases, antibiotic resistance, and chronic human diseases like heart disease and cancer. With regards to infectious diseases, most modern day infections were unknown before the domestication of animals. Industrial agriculture forces a large number of genetically similar animals into unsanitary situations, providing the perfect conditions for viruses to emerge and spread to different species. With regards to antibiotic resistance, the US FDA estimates that each year, 80% of microbial drugs are sold to the meat industry. Countries that have the most microbial resistance also have the highest use of antimicrobials, such as penicillins, tetracyclines, and sulfonamides in animal agriculture. With regards to chronic human diseases, there is extensive evidence that the excessive consumption of animal-based products can lead to chronic diseases such as cardiovascular disease and some types of cancer. The purpose of this article is to further discuss how animal agriculture may be a cause of these current health problems and how adopting a plant-based diet can be a potential solution.
Los escribanos públicos de Ciudad Real al final de la Edad Media. Una aproximación a través de las ordenanzas de la hermandad del año 1489
Authors: Canorea Huete Julián
Published: May 2021

En el presente estudio realizamos un acercamiento a la situación de los escribanos públicos de Ciudad Real (España) durante las últimas décadas del siglo XV. El contexto se caracterizaba por una situación de crisis general de la institución en Castilla y por una gran reforma promovida por la monar-quía. Este trabajo se fundamenta en las ordenanzas aprobadas por los Reyes Católicos en el año 1489 para crear una corporación de escribanos además de diversas cartas remitidas por los monarcas al con-cejo que se custodian en el Archivo General de Simancas. El análisis se estructura en dos grandes partes, la primera sobre cuestiones de organización de la corporación y otra segunda sobre las normas que regulaban el trabajo de los escribanos.
Estudio de la documentación de archivo del encuadernador Joaquín-Gómez Mackinón en la Real Academia de Bellas Artes de San Fernando: 1887-1889
Authors: Carpallo Bautista Antonio
Published: May 2021

Joaquín-Gómez Mackinón fue uno de esos encuadernadores anónimos que trabajaron para la Real Academia de Bellas Artes de San Fernando entre 1887 y 1889, realizando encuadernaciones de lujo para regalar al Papa León XIII y para la Exposición Universal de Barcelona de 1888, sin olvidar las encuadernaciones corrientes en holandesas y papeles salpicados destinadas a la Biblioteca junto a las grandes tiradas de encuadernaciones del Anuario de la Academia. Por lo que observamos que fue un encuadernador que realizaba trabajos de calidad. El artículo trata de dar a conocer algunas notas biográficas de este encuadernador y el análisis de sus encargos, con el objetivo de que se puedan iden-tificar sus encuadernaciones realizadas en otras instituciones. La metodología seguida ha sido el análisis de la documentación de archivo de la Real Academia de Bellas Artes de San Fernando, extrayendo la información relativa a los encargos realizados desde la Academia a este encuadernador; seguidamente se han localizado las encuadernaciones reseñadas en las facturas y recibos, y se han estudiado las téc-nicas constructivas y decorativas y los hierros empleados en la ornamentación, y se ha digitalizado diversas partes de la encuadernación. El resultado final ha sido la obtención de un corpus de hierros empleado por este encuadernador, muy útil para la identificación de otras encuadernaciones en otras instituciones además de la identificación de las diferentes técnicas decorativas y constructivas utilizada.
La «Conspiración de Orleans». Nuevos documentos de una trama polaco-lituana durante la Guerra de los Treinta Años
Authors: Conde Pazos Miguel
Published: May 2021

En junio de 1626, las autoridades hispanas de los Países Bajos interceptaron una serie de cartas que tenían como destino Polonia-Lituania. Se revelaba así la “Conspiración de Orleans”, una trama orquestada por Krzysztof Radziwiłł, uno de los nobles más poderosos de Lituania quien, con el apoyo de las fuerzas protestantes del norte de Europa, trató de introducir la candidatura de Gastón de Orleans en la siguiente elección real en Polonia. En este trabajo describimos los detalles de la trama, totalmente desconocida por la historiografía hispana -a pesar del papel jugado por la corte de Bruselas- y presentamos los dos documentos principales que la desvelaron.
La inscripción latina del túmulo de Luís da Silveira: una auto-imagen sub specie aeternitatis
Authors: Sánchez Tarrío Ana María
Published: May 2021

Estas páginas estudian el sentido y contexto de la inscripción en letra humanística del sepul-cro de Luís da Silveira (1483-1534), en la capilla familiar de la Iglesia Matriz de Góis (Coimbra), inscripción presente en un libro esculpido abierto frente a la efigie del difunto en posición orante de rodillas y que aquí se edita. Se observa la relación, iconográfica y gráfica, del libro-escultura con los Libros de Horas, aun cuando esta inscripción se presenta con grafía a la antica. Por otro lado, se señalan ciertas afinidades con los sepulcros renacentistas italianos y peninsulares, en particular el sepulcro del llamado Doncel de Sigüenza. Además, se explica en qué medida la grafía a la antica responde a la educación humanística de Silveira en la corte de D. Manuel, y cómo la localización en Góis se ajusta al alejamiento de la corte al final de su vida.
Percepção das vulnerabilidades associadas a adesão ao tratamento por adolescentes em hemodiálise
Authors: De Almeida Pereira Santana Cristina Célia , Vitorino Naghettini Alessandra , Vaz de Souza Freitas Ana Tereza , Nolêto Bueno Gina , Oliveira Barreto Gilson , Sousa de Avelar Igor , Mazaro-Costa Renata
Published: May 2021

Adolescentes com Doença Renal Crônica em hemodiálise são submetidos a uma complexa terapêutica que propicia alterações significativas em seu âmbito biopsicossocial, sendo a adesão ao tratamento um dos principais eixos da atenção à saúde para garantir qualidade de vida nessa população. Este estudo objetivou descrever os aspectos percebidos na vivência imposta pela doença, bem como a sua correlação com a adesão ao tratamento. Tratou-se de um estudo descritivo e exploratório com abordagem qualitativa. Os dados foram coletados em duas unidades de diálise entre fevereiro e junho de 2017 por meio de análise documental e entrevistas. Empregou-se o método de Análise do Conteúdo, com auxílio do Software ATLAS. ti (Analysis of Qualitative Data) 7.5.1 para a construção de redes semânticas. A amostra contou com 7 adolescentes, 7 familiares e 15 profissionais. Verificou-se que o contexto é permeado por desfavoráveis condicionantes socioeconômicos, frágil rede de apoio, exclusão escolar, isolamento social, dor e sofrimento, percebidos como vulnerabilidades para a adesão ao tratamento. Em contrapartida, a troca de experiências e a identificação de necessidades individuais sinalizou contribuir para potencializar a adesão à terapêutica pelos adolescentes.
Brincadeiras no parque: Promovendo a saúde infantil por meio do distanciamento tecnológico
Authors: Batista Camargo Isabella Cristina , Baquiega Pessoa Daniela , Carvalho Gonzaga Wigney Júnior , Sabbadin Lemes Darine , Cordeiro e Castro Mariane , Assis Letícia , Fernandes Assis Mariane , Macedo Cabral Isabela , Da Silva Anna Lívya , Dos Santos Odeony Paulo , José Borges Cristiane , Ramos de souza Marise
Published: May 2021

O uso das tecnologias de comunicação como o tablet, smartphone e outros dispositivos de informação, têm se tornado cada vez mais frequente no dia a dia de crianças e adolescentes, dificultando o resgate de atividades lúdicas e brincadeiras que promovam a interação e comunicação fora do ambiente virtual. O presente artigo teve por objetivo relatar a experiência vivenciada pelos membros do grupo pet enfermagem na realização de ações de promoção da saúde, resgatando brincadeiras antigas. O evento foi realizado em um parque municipal, de um município do sudoeste goiano e, proporcionou um momento de lazer e interação entre os participantes e a conscientização do uso limitado da tecnologia presente no cotidiano. Dentre os participantes, 50,5% foram do sexo feminino, sendo 43,3% de faixa etária entre 1 a 5 anos. Foi aplicado um questionário de satisfação aos pais ou responsáveis presentes, trazendo dados relevantes para o programa, no qual as expectativas do público alvo foram atendidas com a realização do evento. Dessa forma é possível aprimorar cada vez mais as atividades desenvolvidas pelo grupo pet enfermagem, levando em conta as necessidades sociais, bem como influenciar positivamente a vida das crianças, para que estas possam vivenciar um ambiente menos tecnológico de forma saudável e interativa.
Preceptor modelo em nutrição clínica – percepção de estudantes e preceptores
Authors: Pinto Fabrício da Paixão Gonçalves , Menezes Ida Helena Carvalho Francescantonio , Naghettini Alessandra Vitorino
Published: May 2021

O preceptor em nutrição clínica atua como exemplo de conduta profissional para o estagiário no cenário da prática. Assim conhecer o perfil do preceptor contribuirá para uma melhor atuação desse profissional no aprendizado dos estudantes. O objetivo do estudo foi caracterizar os atributos do preceptor modelo em nutrição clínica sob a ótica de preceptores e estudantes.   Foi realizado um estudo do tipo exploratório descritivo, de abordagem qualitativa, por meio da realização de entrevistas semiestruturadas com 12 preceptores do Estágio de Nutrição Clínica de uma universidade pública do Centro-Oeste do Brasil e 15 estudantes que cursaram a disciplina. Para a análise dos dados foi utilizada a análise de conteúdo de Bardin. Os dados revelaram uma percepção semelhante entre os dois grupos quanto aos atributos do preceptor modelo, no entanto apenas o grupo dos estudantes percebeu o conceito do preceptor como um espelho para o futuro profissional. O estudo aponta para a necessidade de consolidar o conceito do preceptor em nutrição clínica e aprofundar na percepção do preceptor visto como modelo, para que auxilie na formação da identidade profissional e no desenvolvimento do profissionalismo.
增加值视角我国服务出口贸易的结构特征及国际比较
Authors: 刘 莉 , 盛 厚钦
Published: May 2021

本文基于增加值统计方法，对我国服务出口贸易中的直接出口和间接出口重新进行计算，并通过国际比较，考察我国服务出口贸易的规模发展和结构变迁的特征，得到以下主要结论：考虑到间接出口的存在，我国服务出口贸易的能力被低估；与其他经济体相比，我国服务间接出口对制造业严重依赖，农业和采矿业对服务业间接出口的拉动作用十分微弱；服务业直接出口的占比偏低且持续下降；制造业、农业和采矿业中进口的国外服务增加值比例相对高，国内服务增加值占比有所上升，但是仍然有很大提升空间。
厦门市新旧动能转换发展水平测度研究
Authors: 曾 俊杰 , 杨 国梁 , 黄 慧娴
Published: May 2021

近年来中国经济从高速增长转变为注重结构性增长的“新常态”阶段，要推动中国经济持续健康增长，就要转换经济发展方式以进行供给侧改革。因为新旧动能的转换，能很好地兼顾新兴产业和传统产业的协调发展，更加符合经济发展的高速增长转向高质量发展阶段。本文旨在研究讨论目前厦门市新旧动能转换发展水平，从新旧动能转换发展面临的问题出发，分析并探讨经济增长中应侧重调整的政策性发展措施；并以经济发展的视角出发，从需求侧和供给侧双侧选取10个指标，构建新旧动能转换发展水平的评价指标体系，并运用CRITIC赋值法对新旧动能转换发展的现状进行了测度。研究结果显示厦门市新旧动能转换处于转型的后期阶段，本文并依据测度结果，从资本供给和创新供给两个维度为促进经济增长提供政策性意见。
“两头在外”电商扶贫模式的创新研究
Authors: 封 耀焯 , 连 智华
Published: May 2021

随着精准扶贫不断深入，扶贫面不断收窄，扶贫形式及内容日趋复杂，脱贫攻坚进入“最后一公里”。本文聚焦电商扶贫创新为主脉络，重点选取甘肃省中天创客电子商务有限公司为研究对象，通过经验总结法与探索性研究，深入分析传统电商扶贫的现状和痛点。理论上系统地总结出以电商技能实训为抓手，以全国供应链和全国市场为依托创新的“两头在外”商业模式，实践上解决传统电商扶贫模式在电商基础设施落后、电商人才匮乏、物流仓储体系不完善的深度贫困地区里，不可持续、难以开展的现状和痛点，并创新传统的扶贫模式，构建出“两头在外”电商扶贫新模式，带动精准脱贫。
Senėjimo namuose architektūrinis aspektas taikant biofilinio ir universalaus projektavimo principus:
Authors: Bužinskaitė Deimantė , Gražulevičiūtė-Vileniškė Indrė
Published: May 2021

Darbe pristatoma senėjimo savo gyvenamojoje aplinkoje koncepcija, išskiriamos su jos realizavimu architektūrinėmis priemonėmis susijusios problemos ir galimybės. Šios koncepcijos realizavimo galimybės Lietuvoje, miesto ir kaimo sąveikos zonoje iliustruojamos eksperimentiniu senėjimui savo namuose pritaikyto kvartalo projektu. Eksperimentiniam projektui buvo pasirinktas sklypas buvusio Linkuvos dvaro sodybos teritorijoje, Mosėdžio g., Kaune. Ši glaudų ryšį tiek su gamtine, tiek su urbanizuota aplinka turinti teritorija leido atskleisti biofilinio projektavimo ir universalaus dizaino principų pritaikymo galimybes kuriant fiziniu požiūriu prieinamą ir psichologiškai priimtiną senėjimui namuose pritaikytą aplinką.
Pesquisa de Listeria monocytogenes e identificação dos sorovares em alimentos prontos para o consumo comercializados no estado do rio de janeiro
Authors: Da Silva Débora Alves Ferreira , Carvalho Carla Treece , Brandão Marcelo Luiz Lima , Rosas Carla De Oliveira , Medeiros Valéria De Mello , Tavares Rodrigo Domingos Overa , Vasconcellos Luiza , Lopes Silvia Maria Dos Reis
Published: May 2021

A listeriose e é considerada uma doença de origem alimentar de grande importância em saúde pública. Devido a diversos fatores que acarretam no aumento da oferta de produtos prontos para o consumo, o objetivo deste estudo foi pesquisar L.monocytogenesnestes alimentos e identificar o sorovar dos isolados. Foram analisadas 67 amostras de alimentos prontos para o consumo comercializados no Rio de Janeiro pela técnica de enriquecimento-seletivo descrito no BAM-FDA e a identificação realizada por PCR. De 67 amostras, 14(20,9%) apresentaram contaminação por L. monocytogenes, sendo oito(11,9 %) de queijo tipo minas frescal, quatro(6.0%) de saladas e duas(3.0%) de alimentos provenientes da culinária japonesa. Os sorotipos encontrados foram o 1/2a(n=1), em uma amostra de queijo tipo Minas Frescal, e 1/2b(n=13) nas demais amostras. A presença de L.monocytogenes em alimentos prontos para consumo representa um risco à saúde da população, principalmente os pertencentes aos grupos de risco, como grávidas, idosos e imunossuprimidos.
O futebol business: estádio moderno, torcedores e megaeventos.
Authors: Clemente Rafael Willian
Published: May 2021

O presente trabalho foi construído tendo a relação de torcedores de futebol no estádio como ponto principal. Na esteira do chamado “futebol moderno”, aquele atingido diretamente pelos processos de globalização e mercantilização dos bens culturais, pretendemos identificar determinados processos e possíveis fenômenos capazes de afetar o modus torcedor. Uma das maneiras está diretamente ligada às modificações do espaço – do urbano ao lócus esportivo – propiciadas e incentivadas a partir dos grandes eventos. Sendo assim, nos concentramos em entender as lógicas teóricas e práticas no capitalismo tardio da modernização tanto dos espaços físicos, estruturas, como das relações do público com o esporte. A pesquisa de campo, etnografia, se aliou à teoria e também aos documentos e fontes escritas para a análise final, ao menos em relação à conclusão deste trabalho, pois em se tratando de futebol, a volatilidade do tema faz com que a bola não pare de rolar.
Ensino, pesquisa e extensão na formação docente: a Escola de Música de Manguinhos
Authors: Freire João Miguel Bellard
Published: May 2021

O presente artigo aborda a integração entre ensino-pesquisa-extensão na formação docente.  Um projeto de extensão da área de música da Universidade Federal do Rio de Janeiro foi analisado como exemplo dessa integração, discutindo seus objetivos, sua importância para a comunidade atendida e algumas questões metodológicas. Algumas questões importantes para o projeto e para o campo da Educação Musical também foram debatidas. Destacamos como a indissociabilidade entre ensino-pesquisa-extensão, da forma como ela se dá no projeto, contribui para a formação docente em música, com cada lado do tripé reforçando o outro. Além disso, a atitude de permanente reflexão do docente é valorizada, assim como seu compromisso ético com a transformação social.
QADAR/SINA´AT – „islamska umjetnost“ prvi dio
Authors: Akšamija Mehmed A.
Published: May 2021

Namjera ove analize je započeti raspravu o nekim dijelovima povijesti onog što se deklarira ili titulira kao „islamska umjetnost“, u kritičnom okviru kako okcidentalno- vesterniziranih tako i nekih muslìmānskīh teorijskih pogleda. Analizom i postavljanjem granica u skladu s prevladavajućim autoritetima, pridonijet će se vitalnim modalitetima diskursâ qadar/ṣināʿata, koji su rezolutno ìslāmskī i u skladu s izvorištem (ar. al-mardžaʿili al-maṣdar). Posebno se želi skrenuti pažnja na zalaganje za različitost, upravo zbog okcidentalno-vesterniziranog akademskog nastojanja da se zanemari duh jedinstva i autorefleksivne islamske konstante karakterističnih diskursâ qadar/ṣināʿata uz nametanje umjetne dihotomije sakralnog i profanog, te paradigmatskih pogleda na vrednovanje kreativnog (estetiziranog) postignuća začetnika/dizajnera reprezentacije, odnosno homo islamicusa, kao apsolutnog zapadnjačkog vlasništva (western ownership).

            S druge strane, estetizirano djelanje homo islamicusa u okviru svjesne rekognitivne i kognitivne produktivno-refleksivne orijentacije ima vrlo konkretno povijesno postojanje. Ako za titulaciju „islamska umjetnost“ možemo upotrijebiti poznati Derridaov mot ili grif  ‘il n’y a pas de hors-texte’ (“ništa ne postoji izvan teksta“), za estetizirano djelanje homo islamicusa ne možemo pitati postoji li ili ne postoji. Čini se da bi pravilno pitanje u vezi s modalitetima diskursâ qadar/ṣināʿata glasilo ‘qu'est-ce qu'il y a de hors-texte’? (“što se nalazi izvan teksta? “). Susrešćemo se i s neprimjerenim nazivljem, kao što je npr. upotreba pojma dekorativno kao ekvivalenta za ornamentalno ili arabeskno za estetizirani izraz beskonačnog uzorka, kao i podjelu na centralne i rubne umjetničke produkcije, odnosno središta eurocentrične kulturne moći i tzv. njenu periferiju. Skrenuta je pozornost na okcidentalno-vesternizirano pozicioniranje teorije umjetnosti na vrh evolucije i kreativne zrelosti, što u konačnici ima za cilj jedinstvenu hegemoniju „Novog svijeta“, odnosno podvrgavanje i „kultiviranje“ bilo kojeg neevropskog ili nevesterniziranog entiteta, a posebno kreativnog bivstvovanja unutar klasične tradicije ìslāmske kulture (ar. al-thaqāfah al-islāmiyyah) i ìslāmske civilizacije (ar. al-ḥaḍārah al-islāmiyyah ili al-tamaddun al- islāmiyy).

            Na koncu mora se primjetiti da okcidentalno-vesterniziran način akademskog razmišljanja u ovoj oblasti, te bilo kojih drugih teorija koje djeluju unutar granica indeksnog poretka i taksonomije, uključujući i koncept današnje globalizacije, također predstavljaju sistemske obrasce autoriteta, kontrole i vrednovanja, a time i isključenosti prema drugima. Međutim, takva forma nametanja linearnog ili cikličkog načina tumačenja, se ipak suočava sa vrlo stvarnim izazovima svojstvenim pisanju globalne „historije umjetnosti“ i potpunim odsustvom razumijevanja drugih i drugačijih formi kreativnog izražavanja.
Reforma, a nikako revolucija
Authors: Kulanić Ahmed
Published: May 2021

Djelo Budućnost islama, prema autoru, nastalo je iz pobude i pokušaja ponovne izgradnje odnosa Zapada s muslimanskim svijetom, posebno u svjetlu politike tadašnjeg američkog predsjednika Baracka Obame i njegove politike za „novim putem naprijed“ (str. 6) nakon njegovog „historijskog govora“ u Kairu - kako su to prenijeli zapadni mediji.
Djelo je koncizno i unutar svoja četiri osnovna poglavlja nastoji odgovoriti na nekoliko ključnih pitanja: Kakva je budućnost islama - reformacijska ili revolucijska? Da li su islam i modernost kompatibilni? Koliko je rasprostranjen islamski fundamentalizam i da li je on prijetnja muslimanskim društvima i Zapadu?
Infidel or Paganus? The Polysemy of kafara in the Quran
Authors: Cole Juan
Published: May 2021

This article explores the meaning of the root k-f-r in the Quran, questioning the practice of translating the noun kāfir as “infidel.” It argues for a distinction between the idiomatic phrasal verb kafara bi-, which does mean to reject or disbelieve, and the simple intransitive verb kafara and its deverbal nouns, which are used in the Quran in a large number of different ways. This polysemy is explored through contextual readings of Quran passages. It is argued that the noun kāfir, unlike the verb kafara, is used only with regard to adherents of traditional polytheism and is not deployed in an unmodified way with regard to Jews and Christians. The possible influence on the Arabic kafara of Greek and Latin conceptions is also broached.
Heavy Metal Concentration in underground water due to Fly Ash at Janjgir Champa region in Chhattisgarh
Authors: Kumar Ghosh Manoj , Tiwari Harsha
Published: May 2021

The present study focused on the groundwater contamination due to fly ash disposal of coal-fired thermal power plant into a non-liner ash pond. Tendubhata were selected as study site around ash pond of Marwa thermal power plant. Groundwater samples were collected on random basis using composite sampling method. Ten heavy metals (Ca, Cu, Cd, Cl, Zn, Pb, Ni, Cr, Mn, and Fe) were detected in coal, fly ash, and groundwater samples. Heavy metal concentration in coal and fly ash was assessed by Energy Dispersive X-ray Fluorescence, while AAS was used for groundwater assessment. The observed results revealed the exceeding value of heavy metals prescribed by WHO for groundwater.
Security enabled UAVs for Tech-Agriculture monitoring rice crops using FIBOR architecture
Authors: Lakshmi J V N
Published: May 2021

Unmanned Aerial Vehicles usage has significantly improved in all the sectors. Various industries are using drones as a platform for development with eco- nomic investment. Drastic advancement in design, flexibility, equipment and technical improvements has a great impact in creating airborne domain of IoT. Hence, drones have become a part of farming industry. Indian agriculture economy concentrates more on producing rice as this is considered as a staple food in various states. For increasing the production of rice sensors are equipped in the fields to track the water supply and humidity components. Whereas, identifying weeds, early stages of disease detection, recognizing failed crops, spraying fertilizers and continuous monitoring from bleats, locust and other dangerous insects are some of the technical collaboration with UAVs with respect farming sector. However, use of UAVs in real time environment involves many security and privacy challenges. In order to preserve UAVs from external vulnerabilities and hacking the collaborative environment requires a tough security model. In this proposed article a framework is implemented applying FIBOR security model on UAVs to suppress the threats from data hackers and protect the data in cloud from attackers. This proposed model enabled with drone technology provides a secured framework and also improves the crop yield by 15% by adapting a controlled network environment.
A Review on Analytical Methods for estimation of Apremelast in Bulk, Pharmaceutical Formulation and in Biological Samples
Authors: Shelke Akash , Mankar Someshwar , Kolhe Mahesh
Published: May 2021

Apremilast is approved by USFDA in 2014. It is used in treatment of psoriatic arthritis and other conditions like atopic dermatitis and plaque psoriasis. It is act as an anti-inflammatory agent. It is phthalimide derivative and belongs to class 4 category of BCS system. It is a phosphodiesterase-4 (PDE-4) inhibitor. Analytical methods plays an important role to describe physico-chemical properties of drug. Due to low solubility and low permeability analytical method development and formulation becomes challenging. Till date, there are no standard test methods available to analyze Apremilast. So, a review of the analytical methods for apremilast is carried out. Here we discussed latest analytical methods for estimation of apremilast in bulk, Pharmaceuticals dosage form and in biological samples. In that we study methods like HPLC, UV-Visible spectroscopy, HPTLC, UPLC and mostly used hyphenated technique LC-MS. This review will be helpful for the researcher who is working on apremilast.
A Brief Review of Swimming Endurance and Chronic Stress Model for Evaluation of Adaptogenic activity
Authors: Kishor Braj Nandan , Bhimraj Laware Ravindra
Published: May 2021

Stress is the disturbed homeostatic condition of the organism, and it is represented by non-specific response of the body to any demand imposed on it. Stress brings various changes in physiological condition of the organism, but various mechanism of the body will counteract to maintain homeostasis. In some situations, body’s adaptation to stress is like reward, which is responsible for improvement of body’s performance beyond its capacity. However if organism suffer strong acute or chronic stress, body is unable to maintain homeostasis. Under this condition, various types of diseases and disorders will develop, and even it may lead to death, if it is not managed at proper time. Hazardous stressful situation can be managed by using antistress agent or adaptogen. These agents improve physical and mental working capacity in severe stress circumstances. In different screening models for evaluation of adoptogenic activity, animals are challenged with acute or chronic stress conditions. Various stimulating, stress protective, tonic responses and biochemical markers were measured in evaluation of adoptogenic activity in these animal models.
PENGARUH INTELLECTUAL CAPITAL, CORPORATE SOCIAL RESPONSIBILITY, DAN SALES GROWTH TERHADAP FIRM VALUE
Authors: Adang Ferry
Published: May 2021

This research has a purpose of obtaining empirical evidence regarding the effect of intellectual capital, corporate social responsibility, and sales growth on firm value of the manufacturing companies listed in the Indonesia Stock Exchange (IDX) in 2014 – 2016 period. The research conducted by obtaining 93 samples using purposive sampling method. The result of this research show that the independent variables have effects on firm value (Tobin’s Q) simultaneously (F test). The t test result showed that intellectual capital (VAIC) has a significant positive effect on firm value while the others have no significant effect on firm value
PENGARUH INTEREST RATE, INVESTOR SENTIMENT, FINANCIAL DISTRESS TERHADAP STOCK RETURN
Authors: Wijaya Henryanto
Published: May 2021

The purpose of this research is to know the effect of interest rate, investor sentiment, and financial distress of stock return on manufacturing company listed on the Indonesia Stock Exchange from 2014-2017. The sampling method used in this research used 49 manufacturing company that were selected using purposive sampling method. Data used for this study is obtained from financial statement for the year ended December 31st during 2014-2017. Analysis tool that will be used to analyze the hypothesis with multiple linier regression model is software IBM SPSS (Statistical Product and Service Solutions) version 23.0 for Windows. The result for this research showed that interest rate and investor sentiment have positive and significant effect on stock return, while financial distress has negative and significant effect on stock return.
RELEVANSI NILAI DAN KEMUNGKINAN DETERIORASI: KAJIAN LITERATUR SISTEMATIK
Authors: Kuswanto Randy
Published: May 2021

The paper presents the review of the value relevance literatures used Ohlson model (1995). The popularity of value relevance topic nowadays is principally driven by the adoption IFRS which changed how companies measure its income and assets. Although this topic is still in debate whether it useful or not, this paper tried to conclude a summary from many prior value relevance researches. First, I seek to review some of the significant literature on value relevance during 2009-2019. The emphasis is on results and empirical contributions relating incremental value relevance. The second part of this paper is discussion about eight different studies from more than 10 countries about evidence of value relevance phenomenon in their setting. This paper finds that the concept of value relevance really exists in many countries but it is deteriorating / declining over the period. Further research could test other information to prevent this deterioration of value relevance such as future prospect attributes rather than historical information only
Adalberto Mattos: “Rapins de hontem, artistas de hoje”
Authors:   Universidade Estadual de Campinas, Victor Rossetti Brancato João , Valle Arthur ,   Universidade Federal Rural do Rio de Janeiro
Published: May 2021

Entre janeiro e abril de 1921, o artista e crítico de arte Adalberto Pinto de Mattos publicou na Ilustração Brasileira quatro crônicas sob o título "Rapins de hontem, artistas de hoje." Bastante original em seu conteúdo, as crônicas de Mattos são uma rica fonte acerca do cotidiano da Escola Nacional de Belas Artes em sua fase inicial, permitindo conhecer e/ou imaginar o dia-a-dia dos alunos, a personalidade dos professores, os modos de sociabilidade e até mesmo, os modelos e funcionários da Escola.
Portinari abstrato: os painéis de azulejos no Palácio Capanema (1941-1945)
Authors:   Centro Federal de Educação Tecnológica, Alves Pinto Junior Rafael
Published: May 2021

Nos dedicamos a analisar as alternativas de composição dos painéis em azulejos Conchas e Hipocampos e Estrelas-do-Mar e Peixes, feitos por Candido Portinari para o edifício do antigo Ministério da Educação e Saúde, atual Palácio Capanema. Encomendados em 1941 e executados entre 1941 e 1945, os painéis tornaram-se referências na obra de Portinari: além de executados em azulejos, são composições lastreadas na abstração - o que por si só as distingue no panorama geral da produção do artista.
Representações da Exposição Internacional do Centenário da Independência do Brasil de 1922 e da cidade do Rio de Janeiro nas mídias
Authors: de Azevedo Ribeiro Fernanda
Published: May 2021

O artigo analisa a Exposição Internacional do Centenário da Independência do Brasil de 1922 e a cidade do Rio de Janeiro, sob o enfoque das representações em imagens e discursos nas mídias da época. Contempla os aspectos simbólicos, culturais, sociais, construções de valores, perfis e paradigmas de modernidade, buscando desvendar ideias contidas no que foi então divulgado, e destaca diferentes abordagens sobre a representação como elemento relacionado à questão da identidade.
O impacto da cultura organizacional na gestão do conhecimento para a inovação de processos em serviços
Authors: Bueno Carneiro Herivelton Luís , Streit Rosalvo Ermes
Published: May 2021

Introdução: a inovação é um diferencial competitivo importante no contexto da era do conhecimento e da transformação digital. A gestão do conhecimento, por sua vez, promove, por meio da criação e compartilhamento de ideias, um ambiente favorável à inovação. Neste contexto, é importante que os elementos da cultura organizacional que impactam a gestão do conhecimento para a inovação sejam conhecidos de forma que possam ser melhor trabalhados. Método: por meio de revisão de literatura e pesquisa bibliográfica foram identificados os elementos da cultura organizacional que impactam a gestão do conhecimento para a inovação de processos em serviços. Após, foi aplicado questionário de pesquisa junto a funcionários de uma instituição financeira de grande porte para a análise dos elementos identificados na literatura. Resultados: os resultados permitiram identificar quais elementos da cultura organizacional atuam como estimuladores e quais se constituem em barreiras à gestão do conhecimento para a inovação de processos em serviços na organização pesquisada. Conclusão: com maior adaptabilidade, calibragem mais adequada na aversão ao risco, concessão de maior autonomia aos funcionários e lideranças que valorizem as iniciativas de criação e compartilhamento de conhecimento, e mantenham uma comunicação efetiva, pode-se melhorar a prontidão da organização para a inovação de seus processos de serviços
Puraviekuand Other Translations: Olga Tokarczuk in Japan
Authors: Zielińska-Elliott Anna
Published: May 2021

Between 2010 and 2019, three novels by Nobel Prize-winning author Olga Tokarczuk appeared in Japanese translation. Against the history of Polish literature in Japanese translation, this article tells the story of the discovery of Tokarczuk by her two translators, Hikaru Ogura and Michiko Tsukada, and describes the reception of Tokarczuk’s work in Japan. The essay then moves on to analyze the work of the translators, arguing that Tsukada bases her approach on the use of a higher literary style and the addition of explanations for the reader. This is contrasted with the method of Ogura, who strives to render Tokarczuk’s rhythm and feel, choosing at times to tame Tokarczuk’s occasionally strong language and to leave some names, like Prawiek, untranslated. This last choice stands in contrast to the decisions made by translators into other languages, who instead chose native-language equivalents. I place this strategy within the context of a trend that can be observed in Japanese literary translation more generally, whereby words considered “untranslatable” are simply left in their original forms.
Modelling the impacts of climate change on potential cultivation area and water deficit in five Mediterranean crops
Authors: Montsant Anton , Baena Oriol , Bernárdez Lluís , Puig Jordi
Published: May 2021

Aim of study: To assess the impacts of climate change on local agriculture with a high resolution in a Mediterranean region with a diversity of climates.Area of study: Catalonia (NE Spain).Material and methods: Based on historical meteorological records and a regionalization of the RCP4.5 model created by the Catalan Meteorological Service, the Papadakis agro-climate classification was calculated for two climate scenarios. The changes in agro-climatic suitability and irrigation needs of five typical Mediterranean crops (alfalfa, almond, barley, olive and orange) were analysed. Main results: In the 2031-2050 climate scenario, over 15% of the study area will no longer be adequate for non-irrigated almond or olive, at locations in which they have been traditionally rainfed crops. If irrigation is provided, orange is likely to become agro-climatically suited for the entire Catalan coastline. Were the current crop distribution maintained, irrigation needs may increase on average 16% in the study area in the future scenario.Research highlights: High-resolution GIS data may be combined with Papadakis’ classical method to compare different climate scenarios and detect risks and opportunities for local and regional agriculture.
Philip Sidney’s Stella: The Lady, the Countess, and the Queen
Authors: Alkharji Saleh H.
Published: May 2021

In his poetic sequence, Astrophil and Stella (1591), Philip Sidney dramatizes his speaker’s romantic ambitions of climbing the Ladder of Love. While many academics interpret the sequence as a semi-biographical work, they disagree in evaluating how deep the sequence mirrors Sidney’s life. Traditionally, Astrophil is interpreted as a surrogate for Sidney and, more critically, Stella is read as a fictionalized version of Lady Rich. However, given the inconsistency of literary evidence, a new reading of the sequence emerged and argued that Stella is Sidney’s wife, Frances Walsingham. Although this paper agrees on the surrogacy of the speaker in the sequence, a closer analysis of the poetic language used in Sidney’s sonnets would contradict these Stella’s interpretations. Furthermore, as this paper cites historical documents that confirm the non-romantic relationship between Philip Sidney and Lady Rich, a closer examination of the sequence and the historical context of the Elizabethan Era would conclude that Stella’s real identity is far more complex and multidimensional than to be a mere fictionalized version of Lady Rich or Frances Walsingham. In fact, an investigation of Sidney’s personal life and a close reading of Astrophil and Stella would conclude that Sidney’s Stella is a masked version of Queen Elizabeth.
Reviewer Acknowledgements for Journal of Agricultural Science, Vol. 13, No. 6
Authors: Brown Anne
Published: May 2021

Reviewer acknowledgements for Journal of Agricultural Science, Vol. 13, No. 6, 2021.
A Benchmark to Analyze On-Field Performances: A Case From an Irrigation Scheme in Tunisia
Authors: Hanafi Salia , Bahrouni Hassouna , Albouchi Lassaad , Frija Eymen , Poussin Jean-Cristophe
Published: May 2021

Irrigation systems entail interacting processes that should be considered when analyzing the performances of irrigated areas. When analyzing the cause of performance gaps, one may consider the effect of one factor without taking into account the effect of other influential ones. This study addresses the performance of irrigated areas using a global approach. The analysis includes different factors of the production process and examines the relationship between irrigation and the economic performances of farmers’ irrigated fields. Results showed that technical efficiency (TE), considered as our economic indicator, evaluating the degree to which the inputs are used efficiently, was about 0.85 for fruit orchards, tomato, wheat and 0.66 for olive trees. The on-farm water distribution efficiency (Efarm) that evaluates water lost during its transport to plots was poor and can decrease to 36%. A great potential for improving water management exists. Efarm was not a significant factor for TE. So, Efarm causing substantial water waste has no significant impact on economic performance, the main concern of the farmer. However the easy access to water was a significant factor for TE (p-value < 0.032 in all the cases). The easy access to water is a possible lever for improvement.  We pointed out that irrigation performance in the studied area has no significant impact on economic performance. There is a divergence between the farmer’s interest (the economic efficiency) and the community’s objective to save water through better irrigation performance. Government efforts to provide incentives for farmers for better water management seem to have born no fruit. This study argues for the use of a bechmarking in building global representation adapted to the actual local context. The analysis approch suggests that more attention should be paid to the “water saving program” of Tunisia, by subsidising irrigation investments in a better way and focusing on subsidies that create the most of economic growth.
A SPECIAL CLASS OF UNIVALENT FUNCTIONS WITH NEGATIVE COEFFICIENTS
Authors: AOUF M. K.
Published: May 2021

There are many special classes of univalent functions in the unit disc $U$. In this paper, we consider the special class $P^*(A,B,\alpha,\beta)$, $-1\le B<A \le 1$, $-1 \le B < 0$, $0 \le\alpha < 1$ and $0 < \beta\le 1$, of univalent functions mthe umt disc $U$. And it is the purpose of this paper to show some properties of this class.
ON THE EXTENSOIN OF BERNOULLI, EULER AND EULERIAN POLYNOMIALS
Authors: SINGH S. N. , MISHRA S. S.
Published: May 2021

Here an attempt has been made to extend the Bernoulli, Euler and Eulerian polynomials in multiplication theorem and finite difference formula have been established.
Protection against contamination in mobile collective protection measures, filters
Authors: Harmata Władysław
Published: May 2021

The requirements for mobile collective protection measures for purification elements, against contamination agents were characterized. The methodology and results of penetration tests of the DEHS standard aerosol spray through the material and filtration package as well as dust absorber used in mobile contamination protection agents are presented. Keywords: filtering equipment, leakproofness of mobile protective equipment, HEPA and ULPA class filters.
Epidemiological, Clinical and Molecular Characterization of Human Brucellosis in Bosnia and Herzegovina – An Ongoing Brucellosis Outbreak
Authors: Arapović Jurica , Špičić Silvio , Ostojić Maja , Duvnjak Sanja , Arapović Maja , Nikolić Jadranka , Cvetnić Željko
Published: May 2021

Objective. The aim of this study was to evaluate an ongoing outbreak of brucellosis in southern region of Bosnia and Herzegovina (BIH) on the epidemiological, clinical and molecular level.

Patients and methods. This study included 19 patients affected by brucellosis between 2015 and 2017, in Trebiševo (BIH). Out of 19 patients, 16 were admitted to and treated at the Department of Infectious diseases of the University Clinical Hospital Mostar, while three patients were treated in ambulatory care setting. Epidemiological, clinical and microbiological parameters were investigated. The Rose Bengal test (RBT) positive sera were serologically confirmed by complement fixation test (CFT). We also analyzed blood cultures, and isolates were additionally serotyped. Molecular analyses were performed with Bruce-ladder multiplex polymerase chain reaction (PCR) and multiple locus variable number of tandem repeat analysis of 16 loci (MLVA-16) assay.

Results. Fifteen out of 19 patients had been professionally exposed to the bacterium, while four patients acquired brucellosis without prior contact with infected animals. In seven out of eight (87.5%) patients with localized form of brucellosis, we detected significantly higher values of C-reactive protein (CRP) or erythrocyte sedimentation rate (P<0.001). B. melitensis was isolated from 13/16 (81.3%) blood culture samples, and additionally serotyped as biovar 3. Using MLVA-16 assay, 11 isolates were genotyped. We observed complete genotype matches among 8/11 B. melitensis isolates, while 3/11 isolates differed in Bruce04 locus.

Conclusion. Overall, our study confirms the usefulness of MLVA-16 method in the epidemiological and molecular research of brucellosis during epidemic that, most likely, originated from the same source.
The Medical School of the Catholic University of Croatia: Principles, Goals, Standards and Organization
Authors: Sapunar Damir , Marušić Matko , Puljak Livia , Grković Ivica , Malički Mario , Marušić Ana , Civljak Marta , Tanjić Željko
Published: May 2021

The aim of the study was to present the concept on which the School of Medicine at the Catholic University of Croatia (CUC) will be established. The new School will alleviate the shortage of physicians in Croatia and introduce an innovative form of medical education focused on principles of patient-centered care and social accountability. At the same time, the students will acquire all relevant competencies and levels of knowledge, skills and attitudes that are required by current evidence in medical education, European standards and guidelines for quality assurance at higher education institutions. The four pillars of the CUC Medical School are: 1) distributed medical education that involves health institutions outside major medical centers, 2) the concept of transformative learning, 3) teaching and practicing evidence-based medicine, and 4) implementation of quality management principles supported by information technology solutions for effective management of learning, research and practice. The overall aim of the CUC School of Medicine is to educate and train physicians capable of using best available medical evidence to deliver economically sustainable healthcare that can improve equity and health outcomes in the communities they serve, particularly those that are currently underserved.

Conclusion. The proposed programme is introducing an original system of modern medical education that insists on developing humanistic aspects of medicine, patient-centred care and social accountability, while maintaining all competencies and knowledge levels that a physician should have according to the current understanding of medical education.
Spontaneous Intraparenchymal Lung Haematoma with Active Bleeding, Associated with S. Aureus
Authors: Gerloni Riccardo , Artusi Nicola , Cernic Stefano
Published: May 2021

No abstract available.
International Publications of Authors from Bosnia and Herzegovina in Current Contents Indexed Publications in the Second Half of 2017
Authors: Tanović Nerma
Published: May 2021

No abstract available.
Genomics in Hematology and Oncology Practice
Authors: Srkalovic Gordan
Published: May 2021

No abstract available.
Laboratory Work-Up of Chronic B-Cell Lymphoid Malignancies – A Value-Based Approach
Authors: Shi Min , Dao Linda , Jevremovic Dragan
Published: May 2021

The aim of study was to summarize recent developments in laboratory work-up of lymphomas and discuss their clinical relevance. Diagnosis of lymphoma requires tissue biopsy with adequate work-up by pathologists. Recent developments in laboratory testing have raised the bar  for establishing the diagnosis: more and more testing seems to be required, while the lines between research and clinical practice are being blurred. Academic medical practice is designed to push boundaries and test new hypotheses, which eventually result in improved patient care. Ability to (relatively) cheaply screen for multiple genomic abnormalities using new technologies is luring. Often, however, no change in patient management is pursued based on these results. It is therefore useful to review which testing is truly necessary from the patient’s point of view.

Conclusions. The laboratory work-up of lymphomas in a regular clinical practice requires relatively few tests. Many new tests have prognostic value, but do not necessarily contribute to the patient management.
Adrianus Spigelius’ (1578 – 1625) Ocular Anatomy
Authors: Laios Konstantinos , Mavrommatis Evangellos , Kostoulas George , Manes Konstantinos , Lagiou Efstathia , Lytsikas-Sarlis Pavlos , Piagkou Maria
Published: May 2021

The aim was to study Adriaan van den Spiegel’s ideas on ocular anatomy. He is better known by his Latinized name as Adrianus Spigelius (1578 – 1625). He was a Flemish physician and anatomist who lived and worked in Padua, where in 1605 he was elected to be Professor of Anatomy and Surgery. Chapter IX of book ten of Spigelius’ work on human anatomy, entitled De humani corporis fabrica libri X tabulis aere icisis exornati (1627) was devoted to an anatomical description of the eye. Corresponding to contemporary ideas of the production of knowledge Spigelius endeavoured to enhance Andreas Vesalius’ (1514–1564) anatomy, he did not repeat his predecessor’s theories of ocular anatomy. He conceptualised that the eye has six muscles, five tunics and three humors, while he gave a brief description of ocular physiology combining anatomy and the functional role of the anatomic ocular parts.

Conclusion. He managed to correct Vesalius’ errors and to present ocular anatomy with original notes, which so far, have been ignored and are highlighted now.
The Prognostic Value of SUVmax of 18F-FDG PET/CT in Patients with Metastatic Colorectal Cancer
Authors: Sokolović Emir , Cerić Timur , Cerić Šejla , Bešlija Semir , Vegar-Zubović Sandra , Bešlić Nermina , Sefić-Pašić Irmina , Pašić Anes
Published: May 2021

Objective. The aim of the study was to evaluate the prognostic value of the maximum standardized uptake value (SUVmax) of 18F-Fluorodeoxyglucose (18F-FDG) PET/CT in patients with metastatic colorectal cancer, and to compare it with classical prognostic markers.

Materials and Methods. The study included 70 patients with metastatic colorectal cancer who had not been treated for the metastatic disease. The patients underwent 18F-FDG PET/CT as part of their routine diagnostic reevaluation. During the analysis, the value of the largest tumor diameter and SUVmax was determined for the lesion with the highest SUVmax observed. The values of CEA and CA 19-9 were recorded 7 days before the PET/CT analysis.

Results. SUVmax and Carbohydrate antigen (CA)19-9 were found to be independent prognostic markers of disease progression within 12 months. Based on the Receiver Operating Characteristics (ROC) curve analysis, the patients could be divided into two groups: SUVmax≤4.1 vs. SUVmax>4.1. Patients with SUVmax values of 4.1 or less had significantly better progression-free survival within 12 months with an HR (95% CI) of 2.97 (1.4-6.3), relative to patients with SUVmax values above 4.1.

Conclusion. SUVmax may be used as a novel prognostic marker of disease progression among patients with metastatic colorectal cancer. Values of SUVmax can be used to select patients with a more aggressive type of disease and higher risk for progression within 12 months of PET/CT analysis.