bluuebunny/crossref_metadata_2025 huggingface dataset:
ANKRD29 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that ankyrin repeat domain 29, encoded by ANKRD29, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. ANKRD29 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of ANKRD29 in primary tumors was correlated with overall, distant metastasis-free and recurrence-free survival. Modulation of ANKRD29 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Method of Everything vs. Experimenter Bias of Loophole-Free Bell Experiments
Authors: Morales Manuel
Published: September 2023

Experimenter bias compromises the integrity and advancement of science especially when awarded as such. For example, the 2022 Nobel Prize in Physics awarded the loophole-free experiments that tested physicist John S. Bell’s inequality theorem. These experiments employed the logic of conducting local experiments to obtain local evidence to contradict local realistic theories of nature in order to validate quantum mechanics as a fundamental nonlocal theory. Be that as it may, there was one loophole that was wittingly not tested by the Nobel laureates. The notable exception was Bell’s “super-deterministic” loophole which was validated (2000) (2001) (2002) (2003) (2004) (2005) (2006) (2007) (2008) (2009) (2010) (2011) (2012) nonlocally thus compromising the subsequent Nobel Prize. More importantly, the discovery of two mutually exclusive and jointly exhaustive nonlocal hidden variables revealed why local scientific methods obtain false-positive and false-negative results. With knowledge of this fundamental omission, the inclusion of the nonlocal hidden variables in the local methods used in science can then advance it to be a complete study of nature.
Phần mềm Việt bayesvl chính thức xuất bản trên CRAN
Authors: nghệ Phòng Khoa học-Công
Published: September 2023

Ngày 24/05/2019, chương trình máy tính “bayesvl” chạy trên môi trường R (ngôn ngữ lập trình và môi trường phần mềm miễn phí phục vụ cho tính toán thống kê và đồ họa) do Trung tâm Nghiên cứu Khoa học Xã hội liên ngành (ISR), Trường Đại học PHENIKAA thiết kế và phát triển chính thức được xuất bản trên CRAN – thư viện lưu trữ, phân phối các phiên bản chính thức của R. Phần mềm được xuất bản đánh dấu cột mốc quan trọng cho hành trình hơn 18 tháng lên ý tưởng, thiết kế và triển khai của Trung tâm ISR. (Mã nguồn mở trên Github và CRAN.)
Understanding Broader Community Perspectives on the Scientific Accuracy and Stigma of Personality Trait Labels
Authors: Stanton Kasey , Levin-Aspenson Holly Frances , Emery Noah N , Willis Liana , Myntti Warner , McDonnell Christina G
Published: September 2023

Many labels are used within and across subfields to describe personality disorder (PD) and interpersonally-oriented trait dimensions. For example, “interpersonal disorders” is a suggested alternative label to “personality disorders” in clinical research. Other “dark trait” terms, though not proposed as formal labels for PDs, also are used in different research areas for describing externalizing traits. Terminology changes have been proposed both due to concerns about different descriptors’ validity and their usage potentially being stigmatizing. Improving terminology consensus can also unify research and clinical assessment efforts, and we recruited participants from a range of sources who provided their views on terminology used in PD research towards this goal. This included data from 362 undergraduates, 408 adults recruited online, and 161 adults recruited from the community, and we used targeted recruitment strategies to ensure that individuals with a range of mental health histories were represented in our study. All participants completed questionnaires assessing their personalities and symptoms, and a subset of participants also completed structured clinical interviews. Results indicated that traditional “personality disorders” terminology was viewed favorably compared to other terms both in regard to scientific accuracy and stigma. Additionally, “interpersonal disorders” terminology was also viewed more favorably overall than many other terms, whereas “dark trait” terminology was viewed negatively. Participants’ characteristics (e.g., personality, age) were mostly unrelated to their terminology views. These results provide insight into how various descriptors are viewed by the broader community and provide a foundation for future research investigating how different terms are perceived across contexts.
Understanding Misinformation and Media Manipulation on Twitter During the Voice to Parliament Referendum
Authors: Graham Timothy
Published: September 2023

This study examines discussions about the Voice to Parliament referendum on Twitter between March and May 2023. Analysis of 246,000 tweets sent by 32,453 unique accounts reveals a dominant presence of the Yes campaign, with five times greater tweet volume than the No campaign. The hyperpolarised (Bruns, 2023) discourse on Twitter is marked by misinformation and conspiracy theories stemming from Vote No campaigners and further amplified by attempts to criticise and fact-check it from the Vote Yes camp. Politicians and media outlets play a pivotal role in shaping this discourse, with platforms like Twitter both reinforcing and evolving the ‘racial division’ and ‘hidden agenda’ narratives these elite actors promote. Specifically, Sky News Australia emerges as a significant influencer, amplified by both sides. The No campaign displays a significantly greater proportion of suspicious accounts. An influx of newly created pseudonymous accounts with fabricated or no profile information promote Vote No arguments, engage in trolling and sharing discriminatory content, and spread conspiratorial narratives. We find little evidence of social bots participating in the online discussions. Overall, our findings reveal a media ecosystem fraught with confusion, conspiratorial sensemaking, and strategic media manipulation. This study underscores the challenges of fostering meaningful deliberation in such an environment, highlighting the pitfalls of the current media and political landscape for Australia's liberal democracy, particularly in matters concerning First Nations representation.
AI-Powered Banking: From Customer Service to Risk Management
Authors: Patial Arjun
Published: September 2023

AI-Powered Banking: From Customer Service to Risk Management
CARACTERIZACIÓN Y RIESGO CARDIOVASCULAR DE PACIENTES HIPERTENSOS DE UN PROGRAMA DE HIPERTENSOS DE UNA ENTIDAD PROMOTORA DE SALUD DE LA CIUDAD DE CALI
Authors: Espinosa Jobany Castro , castaño Juan camilo Perea , tobar María Fernanda ruiz
Published: September 2023

Es un problema común en la población, afectando a casi un 30% de la población adulta en los países desarrollados. Suele ser asintomática, fácil de detectar y en algunos casos suele desencadenar condiciones que afectan tanto la calidad de vida del paciente, así como la vida misma. Actualmente la no caracterización de los pacientes hipertensos estudiados impide que reciban el tratamiento adecuado y que se pueda realizar el seguimiento que necesitan por parte del equipo de salud, lo que acrecienta el riesgo de que aparezcan complicaciones cardiovasculares, cerebrovasculares o renales en un futuro, complicaciones que a su vez representan un daño a la calidad de vida del paciente y en muchos casos acortan su vida. Una caracterización ordenada de los pacientes hipertensos en el consultorio del médico de la familia puede revertir esta situación.
The Wisdom of the Crowd Can Unmask Faces
Authors: Carragher Daniel James , Hancock Peter
Published: September 2023

Accurately determining whether two images show the same person is a surprisingly difficult task, which becomes even harder if one or both faces are wearing medical face masks. Previous attempts to improve face matching accuracy have generally had limited success. One brief training program has been shown to improve masked face matching accuracy by 4.9%; however, this increase does not overcome the entire performance deficit caused by masks. Here we investigate whether combining independent identification decisions from different individuals can improve masked face matching performance through the Wisdom of the Crowds Effect (WoCE). Accuracy gains emerged reliably after combining decisions from 3 individuals, culminating in significant improvements of 11-26% among the largest crowds. Despite creating crowds of up to 80 people, half of the eventual improvement had already occurred in crowds of 6 individuals. The WoCE can entirely ameliorate the impairment face masks cause to unfamiliar face matching accuracy.
Enhancing Parental Sensitivity with Spanish-Speaking Latinx Families
Authors: Carrera Pablo , Zablah Franssy M. , de la Rosa Yanira , Benito-Gomez Marta
Published: September 2023

Objectives: Attachment & Biobehavioral Catch-up (ABC) is an evidence-based early intervention promoting attachment security and self-regulation by enhancing parental sensitivity. When scaling up an evidence-based intervention to the community, it is essential to adapt to families’ preferences, including the language of delivery, and to keep testing the intervention's effectiveness with diverse ethnic groups. In this article we aimed to test the effectiveness of ABC in improving parental sensitivity when implemented in Spanish at a community level. Method: The effectiveness of ABC when implemented in Spanish in the community was assessed through pre-post changes in observed parental sensitivity in 79 Hispanic families with children ages 6 months to 4 years. Results: Parental sensitivity increased from pre- to post-test, with a similar effect size to previous studies (d = 0.67). Conclusions: Results and practice implications are discussed, highlighting the importance of fidelity monitoring and supervision of providers.
Testing the Applicability of Idionomic Statistics in Longitudinal Studies: The Example of ‘Doing What Matters’
Authors: Sahdra Baljinder K. , Ciarrochi Joseph , Klimczak Korena , Krafft Jennifer , Hayes Steven C. , Levin Michael
Published: September 2023

This study evaluated idionomic methods for identifying within-person links between therapeutically relevant processes and outcomes, using an ecological momentary assessment dataset of valued action and hedonic well-being (participants (n) = 425; 71.76% female; age = M(SD) = 22.20 (6.85); sampling design: 3-4 prompts per day; total measurements (n) = 6,456). We compared the idionomic approach, integrating idiographic and nomothetic insights, with traditional multilevel modeling (MLM). Our methods included idiographic autoregressive integrative moving average models with an exogenous variable (i-ARIMAX), multivariate random-effects meta-analysis (RE-MA), deep Gaussian mixture modeling (DGMM), and multilevel vector autoregression modeling (Multilevel-VAR). The results showed that i-ARIMAX outperformed MLM in capturing within-person heterogeneity in the links between valued action and affect variables. Increases in values-based living were positively related to hedonic well-being but this effect showed a high degree of heterogeneity. A sub-group was identified, which we labeled the ‘Stoics,’ whose daily engagement in valued actions did not produce higher hedonic well-being (e.g., lower sadness or higher joy). Multilevel-VAR further revealed that for Stoics, stressful situations were linked to valued action, but not hedonic well-being. For Non-Stoics, valued action was less likely in stressful situations, but when valued action did occur it was associated with more joy and less sadness. The study offers initial evidence suggesting the superiority of an idionomic approach over a purely nomothetic one in capturing diverse pathways to clinically relevant outcomes. Idionomic methods may be useful or even necessary in personalizing psychological interventions, and thus may need to be considered by researchers and practitioners alike.
Partisan sorting, fatalism, and Supreme Court legitimacy
Authors: Davis Nicholas , Hitt Matthew P.
Published: September 2023

This paper studies the contemporary contours of Supreme Court legitimacy. First, we construct a dataset of surveys from 2012-2024 to show that diffuse support now diverges among partisans; we then analyze an original, six-wave panel survey that documents the stability of this partisan sorting. Second, we unpack the direct and indirect effects of partisanship on legitimacy: Democrats are more cynical about the Court, disapprove of its outputs, and view obedience to the law differently than Republicans, which contributes to the profound partisan gap in legitimacy. Finally, we reevaluate the relationship between specific and diffuse support by introducing a new measure of specific support, which shows that “fatalistic” views of the Supreme Court contribute to low levels of legitimacy. Today, Democrats’ pessimism toward the Court has eliminated decades of positivity and goodwill. This fatalistic sorting among large swaths of the public implies that the Court’s perceived authority now rests on weak and polarized foundations.
The effect of labelling on judgements of psychopathy as moderated by mental health stigma and baseline attitudes of psychopathy
Authors: Vione Katia , Wallace Louise , Mooney Robyn , Thatcher Ashleigh , Colman Rory , Danton Ian , Geier Veronika , Rigo Agnes , Commarmond Alexandra , Falcão Raphael Patrício Andrade , Hammond Courtney , Sparks Brandon , Fido Dean
Published: September 2023

BackgroundEmpirical knowledge of psychopathy is often misrepresented in the media and miscommunicated to the general public. This can have practical implications in legal settings. This research investigated how the labels used when discussing individuals characterised by psychopathic traits impacts lay judgements and attributions of them. MethodsParticipants (n = 477) read a randomised vignette that differed by the sex of the depicted character and the label used to describe them; namely ‘no label’, ‘having a clinical diagnosis’, and ‘displaying psychopathic personality traits’. Measures of mental health stigma and baseline beliefs about psychopathy were used as moderator variables.ResultsResults indicated that participants judged male (relative to female) characters, and those labelled as having either a psychopathy diagnosis or psychopathic personality traits (relative to no label conditions) more harshly. No interaction was found between these main effects, and neither mental health stigma nor beliefs about psychopathy moderated these differences. ConclusionWe call for more education around psychopathy targeted towards the general population; with results conveying international practical applications around the reporting and depiction of psychopathy in the media and within legal settings.
Development of a short version of the Spielberger state and trait anxiety inventory for pregnant women
Authors: Stefana Alberto , Cena Loredana , Trainini Alice , Trainini Alice , Palumbo Gabriella , Mirabella Fiorino , Gigantesco Antonella
Published: September 2023

The Spielberger state-trait anxiety inventory (STAI) is a widely recognized tool for assessing state and trait anxiety components in the general population. While reliable and valid, each scale in the STAI has 20 items, which limits its usability in certain real-world clinical settings. Additionally, certain items can inaccurately increase anxiety scores among expectant women. This study aimed to develop a concise yet dependable and valid version of these scales tailored for pregnant individuals. We engaged 1,158 expectant women who completed the STAI and other assessments to determine criterion validity. Our methodology incorporated item response theory to select the most discriminating items for pregnant people, confirmatory factor analysis to evaluate the fit of the factor solution for the abbreviated versions, and k-fold cross-validation to ensure the robustness of the models. Additionally, Bland-Altman regressions and plots assisted in gauging score accuracy, and receiver operating characteristic analyses determined discriminative validity. We also set clinical change benchmarks. The resulting five-item STAI short forms manifested robust psychometric attributes and reliability, providing a theoretically grounded and reliable anxiety assessment during pregnancy. This can be effectively applied in obstetric and gynecological settings, offering a streamlined response experience for expectant women.
Adoptive Parents’ Lived Experience of Adoption and Adopted Adolescents’ Social Adjustment
Authors: Costa Isabel-Sofia , Barbosa-Ducharne Maria , Palacios Jesús , Soares Joana Lara
Published: September 2023

In recent years, adoption research has been paying increased attention to the lived experience of adoption, mainly from the adoptees’ perspective. This study considers the adoption experience as lived by the adoptive parents. Also, typically, parent-child influences have been described following the cascade metaphor, with downstream influences from parents to children. Nevertheless, upstream influences are also possible so that the way adopters experience adoption can be influenced by the adoptees’ adjustment and experiences. In this article, involving 71 adoptive families, the hypothesis of interdependent influences is explored considering the adopters' lived experience of adoption and the adoptees’ social adjustment.
Using Mobile Technology in Student Learning and Advanced Thinking Skills
Authors: Nuphanudin Nuphanudin , Herlina Lina , Sari Mutia Alviena , Komariah Aan , Siregar Atika Mei Fani , Kristiawan Muhammad
Published: September 2023

To meet their learning demands in a university context, students' regular usage of digital technology has raised the need for personalization and diversity. Mobile devices are expanding into the mainstream and giving students more opportunities. Students are at ease utilizing digital technology and rapidly and easily pick up new technology. Students are engaged in their education outside of the typical classroom setting when mobile technology is used. Higher education institutions have recently supported students' usage of mobile technology to foster learning and growth. The educational options offered by mobile technology can help students succeed in higher education. The objective of this study is to examine the relationship between college students’ academic use of mobile technology and their superior thinking skills through their active participation and learning efforts. The sample consisted of 656 students from a university in West Java, and the data were analyzed using a structured least squares equation model. The results show that the use of mobile technology in learning directly affects students’ thinking skills, in addition to their learning effort and active participation in the classroom. These findings provide valuable information for higher education institutions seeking to introduce interactive and technology-integrated environments.
Learning Organization and Innovation Coaching Model Organizational Agility Approach: A Case Study
Authors: GÜRSEV Samet
Published: September 2023

In today's world, Industry 4.0 and its effects are seen, organizational agility has become a mandatory item for companies serving around the world. The perception of customer focus and quality, which started with the perception of Total Quality Management, spread rapidly and turned into a world in which agile companies take place with the effect of the competitive market. Companies declare that they are agile by performing agile rituals and framework applications. However, the debate continues on what should be the real organizational agility success and what it should change, which gives us maturity. In the research, the concepts of organizational agility and learning organization were explained in detail, and an innovative model recommendation was made regarding the currently recommended agile methods by adding the aim of innovation. The research model recommendation carried out shows important criteria for the issues that agile processes should focus on in the changing world with the effects of Industry 4.0. The results of the model, which was tested on Agile Teams, are also given in detail.
İpekböceği (Bombyx mori L.) Yetiştiriciliğinde Yapay Yem Karışımlarının Kullanımı
Authors: GÜREL Fehmi
Published: September 2023

Evcilleştirilmiş ipekböceği, Bombyx mori L., binlerce yıldır ipek üretimine büyük katkı sağlayan ekonomik açıdan en önemli böceklerden birisidir. İpekböceği’nin temel özelliklerinden biri tek tip bir besin kaynağıyla beslenmeyi tercih etmesidir. Taze dut yaprakları ipekböceği larvalarının tek doğal besin kaynağıdır. Dut yapraklarının tüm yıl boyunca bulunmaması ipekböceği yetiştiriciliğini ve koza üretimini ciddi şekilde sınırladığından, ipekböceği larvalarının yapay bir yemle beslenmesi hep gündemde olmuştur. İpekböceklerinin tüm larva döneminde yapay yemlerle beslenmesi ilk kez 1960 yılında başarılmıştır. Ancak ipekböceği larvaları bu yapay yemlerle beslendiğinde larvaların büyüme ve gelişmesi gerilemiş, küçük kozalar üretmişlerdir. Daha sonraki yıllarda pek çok gelişmenin ardından özellikle Japonya'da genç ipekböceği larvalarının 1. ve 3. yaş dönemleri arasında yapay yemle beslenmesi yaygınlaşmıştır. Günümüz ipekböceği yetiştiriciliğinde yapay yemlerin maliyetleri nedeniyle tüm larva dönemleri boyunca kullanılamayacağı genel olarak kabul edilmiştir. Bu derlemede, ipekböceği yetiştiriciliğinde yapay yem karışımlarının temel bileşenleri, formülasyonları ve hazırlanması ile ilgili ayrıntılara yer verilmiş, ayrıca bu konudaki güncel bilimsel çalışmalar da özetlenmiştir.
Evaluation of Some Antidepressants as Inhibitors of Thioredoxin Reductase Enzyme, which is an Anticancer Target
Authors: FELEK İkranur , AKKEMİK Ebru
Published: September 2023

Thioredoxin reductase (TrxR) is an enzyme that is involved in many metabolic pathways from detoxification to reduction of radicals by catalyzing the reduction of thioredoxin, and is therefore associated with many physiological processes, including cancer. Inhibitors of this enzyme are considered anticancer targets. In past studies, some antidepressants have been found to have anticancer effects through various mechanisms, and therefore the reuse of antidepressants as anticancer drugs has attracted the attention of researchers. In this study, it was aimed to investigate the inhibition effect of some antidepressants (neferine (1), amoxapine (2), mirtazapine (3), agomelatine (4), trazodone hydrochloride (5), amitrptyline hydrochloride (6)) on cytosolic rat liver TrxR activity. The inhibition effects of these molecules were determined by IC50 and Ki values. 1 (IC50:220 µM, Ki: 1.3±0.79 µM), 2 (IC50:337 µM, Ki: 5.2±2.1 µM), 3 (IC50:487 µM, Ki: 5.6±1.99 µM) and 4 (IC50: 545 µM, Ki: 7.0±1.83 µM) exhibited potent inhibition effect on cytosolic rat liver TrxR. As a result, it was hoped that these results might contribute to both explaining the anticancer mechanism of these antidepressants and synthesizing new TrxR inhibitors with anticancer effects
Farklı Sürelerde Uygulanan Ultrases İşleminin S. boulardii’nin Probiyotik ve Antioksidan Özelliklerine Etkisi
Authors: GOKTAS Hamza , TURALİ Demet , AĞAN Cansu , SAĞDIÇ Osman
Published: September 2023

Bu çalışmada farklı sürelerde (5, 15, 30 ve 60 dk.) ultrases uygulamasının S. boulardii’nin probiyotik ve antioksidan özellikleri üzerindeki etkisi araştırılmıştır. Ultrases uygulaması sonucunda S. boulardii’nin agregasyon yüzdesinde artış tespit edilmiştir ve 24 saatlik inkübasyon sonunda minimum agregasyon yüzdesi %96 olarak belirlenmiştir. Suşların hidrofobisite yüzdeleri %7,94 ile %11,55 arasında değişmiş olup 60 dk.’lık ultrases uygulaması sonucunda S. boulardii’nin hidrofobisite yüzdesinde düşüş olmuştur. Ultrases uygulaması sonucunda S. boulardii’nin düşük pH ve safra tuzu direncinde önemli derecede azalma tespit edilmiştir (P≤0,05). 30 ve 60 dk.’lık ultrases uygulması S. boulardii’nin mide koşullarına direncini arttırmıştır. Ultrases uygulanan ve uygulanmayan S. boulardii’nin genel canlılık düzeyi %85’in üzerinde tespit edilmiştir. Test edilen antibiyotik ajanlara karşı farklı direnç düzeyler belirlenmiştir. Ultrases uygulaması sonucu S. boulardii’nin antioksidan aktivitesi artmıştır ve antioksidan aktivite sonuçları %13,25 ile %39,37 arasında değişmiştir. Sonuç olarak elde edilen sonuçlar ultrases uygulamasının S. boulardii’nin probiyotik ve antioksidan özelliklerinin geliştirilmesi için kullanılabileceğini göstermiştir.
Students' and Lecturers' Perceptions on The Implementation of Online Learning During Covid-19 Pandemic
Authors: Prastyo Yanuar Dwi , Harahap Alvita
Published: September 2023

The objective of this research is to explore studentsâ€™ and lecturersâ€™ perceptions on the implementation of online learning during the Covid-19 pandemic at the English Department of Universitas Bandar Lampung. This research was qualitative research and used questionnaires and interviews as its instruments of data collection. The results of the research showed that the students' and lecturers' perceptions are quite satisfied with the implementation of online learning during the Covid-19 pandemic at the English Department of Universitas Bandar Lampung. Students and lecturers have similar perceptions on flexibility indicators, including accessibility and time management. Therefore, there are also differences between the student's and lecturers' perceptions of effectiveness and problems. They also give some suggestions for students, suggestions for lecturers, and suggestions for the university so that the quality of online learning that is already good enough can be improved again so that some of the shortcomings can be minimized in the future.
Establishment and multicenter external validation of a risk prediction model for de novo intracranial aneurysms based on a systematic review and meta-analysis of 19 cohorts
Authors: Tan Jiahe , Song Rui , Su Jun , Wu Hongyu , Fu Wenqiao , Ma Yinrui , He Zhaohui
Published: September 2023

OBJECTIVE

A de novo intracranial aneurysm (IA) is a second, new IA that develops in patients with IAs distant from where the initial IA was detected. This study aimed to identify risk factors for de novo IA formation and establish and externally validate a multicenter risk prediction model for de novo IAs.

METHODS

A systematic review and meta-analysis of existing de novo IA cohorts was conducted to form the derivation cohort. The risk ratios and 95% CIs of each risk factor were calculated. In addition, risk scores included in the model were calculated based on the statistically significant risk factors with their weightings. Then the model was validated in a multicenter external cohort of Chinese patients, and receiver operating characteristic and calibration curves, decision curve analysis, and Kaplan-Meier curves were used to evaluate the model.

RESULTS

Nineteen studies with 9351 patients, of whom 304 patients (3.25%) developed de novo IAs, were included in the derivation cohort. These patients developed de novo IAs at 2.5–18.5 years during a total follow-up of 3.3–18.8 years. The statistically significant risk factors were age < 60 years, female sex, smoking history, family history of IAs, multiple IAs at initial diagnosis, and initial IAs in the middle cerebral artery, with risk scores of 4, 5, 2, 6, 3, and 3, respectively. Then, a multicenter external cohort comprising 776 patients, of whom 45 patients (5.80%) developed de novo IAs, was included in the validation cohort. De novo IAs formed in these patients at a mean of 5.25 years during a mean follow-up of 6.19 years. The area under the curve of the model was 0.804, with a sensitivity of 0.667 and specificity of 0.900, at a cutoff value of 13. The calibration curve, decision curve analysis, and Kaplan-Meier curves also indicated good performance of the model.

CONCLUSIONS

This prediction model is a convenient and intuitive tool for identifying high-risk patients with de novo IAs. Reasonable use of the model can not only aid in clinical decision-making but also play a positive role in the prevention of aneurysmal subarachnoid hemorrhage to a certain extent.
Survival and neurological outcomes after stereotactic biopsy of diffuse intrinsic pontine glioma: a systematic review
Authors: Dalmage Mahalia , LoPresti Melissa A. , Sarkar Prottusha , Ranganathan Sruthi , Abdelmageed Sunny , Pagadala Manasa , Shlobin Nathan A. , Lam Sandi , DeCuypere Michael
Published: September 2023

OBJECTIVE

Diffuse intrinsic pontine gliomas (DIPGs) are aggressive and malignant tumors of the brainstem. Stereotactic biopsy can obtain molecular and genetic information for diagnostic and potentially therapeutic purposes. However, there is no consensus on the safety of biopsy or effect on survival. The authors aimed to characterize neurological risk associated with and the effect of stereotactic biopsy on survival among patients with DIPGs.

METHODS

A systematic review was performed in accordance with PRISMA guidelines to identify all studies examining pediatric patients with DIPG who underwent stereotactic biopsy. The search strategy was deployed in PubMed, Embase, and Scopus. The quality of studies was assessed using the Grading of Recommendations, Assessment, Development and Evaluation system, and risk of bias was evaluated with the Cochrane Risk of Bias in Nonrandomized Studies–of Interventions tool. Bibliographic, demographic, clinical, and outcome data were extracted from studies meeting inclusion criteria.

RESULTS

Of 2634 resultant articles, 13 were included, representing 192 patients undergoing biopsy. The weighted mean age at diagnosis was 7.5 years (range 0.5–17 years). There was an overall neurosurgical complication rate of 13.02% (25/192). The most common neurosurgical complication was cranial nerve palsy (4.2%, 8/192), of which cranial nerve VII was the most common (37.5%, 3/8). The second most common complication was perioperative hemorrhage (3.6%, 7/192), followed by hemiparesis (2.1%, 4/192), speech disorders (1.6%, 3/192) such as dysarthria and dysphasia, and movement disorders (1.0%, 2/192). Hydrocephalus was less commonly reported (0.5%, 1/192), and there were no complications relating to wound infection/dehiscence (0%, 0/192) or CSF leak (0%, 0/192). No mortality was specifically attributed to biopsy. Diagnostic yield of biopsy revealed a weighted mean of 97.4% (range 91%–100%). Of the studies reporting survival data, 37.6% (32/85) of patients died within the study follow-up period (range 2 weeks–48 months). The mean overall survival in patients undergoing biopsy was 9.73 months (SD 0.68, median 10 months, range 6–13 months).

CONCLUSIONS

Children with DIPGs undergoing biopsy have mild to moderate rates of neurosurgical complications and no excessive morbidity. With reasonably acceptable surgical risk and high diagnostic yield, stereotactic biopsy of DIPGs can allow for characterization of patient-specific molecular and genetic features that may influence prognosis and the development of future therapeutic strategies.
The life and legacy of John Robert Cobb: the man behind the angle
Authors: Botterbush Kathleen S. , Zhang Justin K. , Chimakurty Pranav S. , Mercier Philippe , Mattei Tobias A.
Published: September 2023

In 1934, Dr. John Robert Cobb moved to New York to serve as the Gibney Orthopedic Fellow at the Hospital for the Ruptured and Crippled, now known as the Hospital for Special Surgery. In this role, Cobb was faced with a unique task that would shape not only his personal career but also the fields of scoliosis and spine care: to design the first scoliosis specialty clinic. He critically reviewed the treatment methods for scoliosis outlined by prior pioneers in spine surgery and kept his own meticulous records of diagnoses, treatments, and radiographs. Cobb’s work culminated in major contributions to spine surgery that are highly relevant to this day, including the Cobb angle and the Cobb elevator. In this detailed analysis of the career and academic legacy of Dr. John R. Cobb, the authors examine in detail the historical events surrounding Cobb’s great contributions to spine surgery and their lasting impact on our specialty, as well as unique aspects of his personal life. This historical vignette constitutes the first comprehensive analysis of the life, career, and academic legacy of Dr. John R. Cobb, the man behind the angle.
ANALYSIS OF WORD SEARCH ALGORITHMS IN THE DICTIONARIES OF MACHINE TRANSLATION SYSTEMS FOR ARTIFICIAL LANGUAGES
Authors: Barkovska Olesia , Havrashenko Anton
Published: September 2023

The paper is devoted to the development of an organizational model of the machine translation system of artificial languages. The main goal is the analysis of word search algorithms in the dictionary, which are significant elements of the developed machine translation system at the stage of improvement of new dictionaries created on the basis of already existing dictionaries. In the course of the work was developed a model of the machine translation system, created dictionaries based on texts and based on already existing dictionaries using augmentation methods such as back translation and crossover; improved dictionary based on algorithms of n-grams, Knuth-Morris-Pratt and word search in the text (such as binary search, tree search, root decomposition search). In addition, the work implements the possibility of using the prepared dictionary for translation. The obtained results can improve existing systems of machine translation of the text of artificial languages. Namely, to reduce the operating time by approximately 20 times when switching from the balanced tree algorithm to other logarithmic algorithms. The practical significance of this work is the analysis and improvement of text augmentation algorithms using algorithms of binary search, hashes, search tree, and root decomposition.
ЕФЕКТИВНЕ ПАРТНЕРСТВО З БІЗНЕСОМ ЯК ЗАСІБ ПІДВИЩЕННЯ ЯКОСТІ ОСВІТИ В ГАЛУЗІ ІНФОРМАЦІЙНИХ ТЕХНОЛОГІЙ
Authors: Переймибіда Андрій , Рашкевич Марія
Published: September 2023

The quality of education in the field of information technology depends on the use of modern tools of cooperation between universities and leading companies. Micro-credentials, which are rapidly spreading throughout the world, are among the new innovative tools. On the example of the SoftServe company, the experience of using dual study, non-formal study, professional training of teachers is analyzed. Problems are identified and models of SoftServe cooperation with universities are described, which increase the employability of graduates.
VOICE ASSISTANT FOR FINDING ITEMS IN CLOTHING STORE
Authors: Shymanskyi Volodymyr , Kazonnikova Nikoletta
Published: September 2023

The paper presents the use of machine learning in audio file processing, the use of neural networks to recognize voice commands, and the development of a voice assistant for finding products in a clothing store.

The purpose of the work is to develop a voice assistant for finding items in a clothing store.

As a result, a dataset containing 30 categories and 3095 audio recordings was created, a neural network model was trained using the collected data, and an accuracy of 96.02% was achieved; WER: 0.0398; CER: 0.0087. The model was integrated with the search system into the voice assistant API, which allows you to record from a microphone, convert audio to text, break the text into keywords, and search the database using the obtained keywords. The speech recognition system has shown stable and high accuracy when recording from a microphone. This provides users with reliable and accurate recognition results even when using simple microphones. Search allows you to find results by keywords and names of items, and there is a function to recommend similar items if nothing was found at the user's request. The system's flexibility allows it to understand language contexts and does not depend on the order of words in a phrase, as the search is performed by keywords separately. The research analyzes the literature and compares existing approaches to voice command recognition. The methods of audio signal processing are described. The problem of searching for items in a clothing store was analyzed, and the current state of the market and demand for the technology were investigated. The practical value is that the developed voice assistant is specialized and optimized for searching for goods in a clothing store, allows solving the task of finding goods according to specified criteria, and simplifies the search task for different groups of people.
PENGARUH PENGUNGKAPAN ENVIRONMENTAL, SOCIAL DAN GOVERNANCE (ESG) TERHADAP KINERJA PERUSAHAAN PADA PERUSAHAAN SUB SEKTOR PERTAMBANGAN BATU BARA PERIODE 2017-2022
Authors: Durlista Machillah Afany , Wahyudi Ickhsanto
Published: September 2023

This study aims to analyze and test the effect of Environmental, Social, and Governance (ESG) disclosures on company performance. Company performance in this study consists of operational performance (ROA), financial performance (ROE), and market performance (Tobin's Q). ESG disclosure standard guidelines use the Global Reporting Initiative (GRI). The population of this study were coal mining sub-sector companies listed on the IDX from 2017 to 2022. The sample selection used purposive sampling with 5 companies and used multiple linear regression data analysis. The results of this study indicate that environmental disclosure has a positive effect on operational performance and financial performance, but has no effect on market performance. Social disclosure has a positive effect on market performance, but does not affect operational performance and financial performance. While governance has a positive effect on financial performance and market performance, it has no effect on operational performance. The implication is that increasing awareness and compliance with corporate social responsibility towards the environment, social and governance of the impact of the company's operational activities is a way for the company's sustainability
PENGARUH GOOD CORPORATE GOVERNANCE TERHADAP PROFITABILITAS DAN NILAI PERUSAHAAN
Authors: Anggraeni Natasya Salwa , Krisnawati Astrie
Published: September 2023

Indonesia merupakan salah satu negara yang disebut dengan negara agraris, yang berarti sektor pertanian berperan penting dalam perekomian nasional. Jika penerapan good corporate governance sudah terlaksana dengan baik, namun juga sebagai pasar modal bagi perusahaan untuk bisa melihat kinerja saham yang akan mempengaruhi kinerja keuangan. Tujuan dari penelitian ini adalah untuk mengevaluasi dan mendefinisikan dampak tata kelola perusahaan yang baik pada perusahaan-perusahaan di sub sektor pertanian yang menjadi bagian dari BEI antara tahun 2017 dan 2021. Faktor profitabilitas dan nilai bisnis yang ditentukan oleh ROA dan Tobin's Q. Baik dalam penelitian deskriptif maupun kausal, metodologi ini menggunakan teknik kuantitatif. Purposive sampling adalah metode untuk memilih sampel dari sampel non-probability. Penelitian ini termasuk dalam kategori penelitian data panel, tergantung kapan dilakukannya.Penelitian ini menemukan bahwa baik ROA maupun Tobin's Q secara signifikan dipengaruhi oleh keberadaan karakteristik tata kelola perusahaan yang efektif seperti komisaris independen dan komite audit. Setiap variabel independen mempengaruhi dan tidak mempengaruhi hasil. Setiap variabel independen ada yang mempengaruhi dan tidak mempengaruhi hasil. Hal ini semakin menunjukkan pentingnya tata kelola perusahaan yang efektif dalam meningkatkan laba dan nilai pasar perusahaan.
PENGARUH KEPEMIMPINAN PATERNALISTIK DAN KEPEMIMPINAN MELAYANI TERHADAP KEPUASAN KERJA DAN KOMITMEN ORGANISASI : PERAN MEDIASI PERSEPSI SKALA POLITIK ORGANISASI
Authors: Indartinah Septi , Syah Tantri Yanuar Rahmat , Rojuaniah Rojuaniah , Hafidz Ikramina Larasati Hazrati , Azizah Fadilah Nur
Published: September 2023

Penelitian ini bertujuan untuk menunjukkan tentang pengaruh gaya kepemimpinan paternalistik dan kepemimpinan melayani terhadap komitmen organisasi dan kepuasan kerja, dengan persepsi kebijakan organisasi berfungsi sebagai faktor mediator. Populasi dalam penelitian ini adalah karyawan yang memiliki pemimpin dengan jumlah responden sebanyak 153 orang. Untuk menghasilkan temuan ini, peneliti menggunakan  teknik analisis Structural Equation Model (SEM), yang membantu dalam mengevaluasi hipotesis dan hipotesis yang diusulkan. Kepuasan kerja karyawan sangat dipengaruhi oleh gaya kepemimpinan dalam melayani dalam memberikan prioritas kepada timnya, dengan mendengarkan dan memperhatikan apa yang dibutuhkan, seorang pemimpin dapat membuat karyawan merasa dihargai dan termotivasi untuk bekerja lebih keras. Namun, kepuasan kerja tidak berkorelasi signifikan dengan pendekatan kepemimpinan yang melayani. Studi ini menekankan pentingnya mendorong loyalitas dan kepercayaan pelanggan untuk meningkatkan niat membeli kembali. Selanjutnya, persepsi organisasi politik yang mempengaruhi komitmen organisasi dengan karyawan merasa skala politik organisasi di tempat kerja, seperti persaingan tidak sehat atau pemilihan berdasarkan hubungan pribadi daripada kinerja pekerjaan, akan berdampak negatif terhadap komitmen mereka terhadap organisasi. Gaya kepemimpinan paternalistik tidak berdampak positif terhadap komitmen organisasi karena metode penelitian ini lebih dominan dan otoriter serta memberikan lebih sedikit ruang bagi karyawan untuk berpartisipasi aktif. Implikasi praktis dari penelitian ini adalah bahwa perusahaan harus memprioritaskan budaya dan prinsip organisasi, mendukung kepemimpinan paternalistik, dan strategi persepsi politik organisasi yang akan meningkatkan kepuasan kerja dan komitmen karyawan. Gaya kepemimpinan tertentu dan penerapan strategi persepsi politik organisasi dapat membantu meningkatkan kepuasan karyawan dan komitmen mereka terhadap organisasi secara keseluruhan. Penelitian di masa depan dapat memperluas cakupan variabel dan sampel yang lebih luas untuk memperdalam pemahaman tentang variabel lain, seperti lingkungan kerja yang mendukung, peluang untuk kemajuan dalam karier, dan pembagian sumber daya yang adil, yang dapat memiliki pengaruh signifikan terhadap komitmen kerja seseorang di tempat kerja.
Cover Jurnal
Authors: Jurnal Pengelola
Published: September 2023

Cover Jurnal Edisi Oktober 2021
Pengelola Jurnal
Authors: Jurnal Pengelola
Published: September 2023

Pengelola Jurnal
Wymogi formalne zgłoszenia wierzytelności według artykułu 240 prawa upadłościowego i naprawczego
Authors: Wrzaszcz Paweł
Published: September 2023

Zgłoszenie wierzytelności jako prawny środek dochodzenia roszczenia w postępowaniu upadłościowym, podobnie jak pozew, podlega ścisłym, określonym przez ustawodawcę wymogom formalnym (art. 240 prawa upadłościowego i naprawczego). Nie bez znaczenia dla niniejszych rozważań istotne jest ustalenie sankcji, z jakimi ustawodawca wiąże niezachowanie przez wierzyciela wymogów formalnych zgłoszenia wierzytelności. Ze względu na kategorię podmiotów występujących ze zgłoszeniem wierzytelności można wyróżnić kategorię pierwszą, obejmującą wierzycieli, którzy są traktowani mniej restrykcyjnie przez ustawodawcę, tj. osoby fizyczne, które nie są przedsiębiorcami oraz kategorię drugą, tj. przedsiębiorców i profesjonalnych pełnomocników.
Sprawozdanie z konferencji naukowej i spotkania opłatkowego Stowarzyszenia. Lublin, 16 stycznia 2010 roku
Authors: Lewicka Mariola
Published: September 2023

Dnia 16 stycznia 2010 roku w Katolickim Uniwersytecie Lubelskim Jana Pawła II odbyła się konferencja naukowa zorganizowana przez Stowarzyszenia Absolwentów i Przyjaciół Wydziału Prawa KUL oraz Katedrę Kościelnego Prawa Publicznego i Konstytucyjnego KUL. Konferencję otworzył ks. prof. dr hab. Józef Krukowski, Przewodniczący SAWP KUL, który bardzo serdecznie powitał przybyłych członków i przyjaciół Stowarzyszenia i zaprosił wszystkich do uczestnictwa w sesji naukowej i do wspólnego dzielenia się opłatkiem. Wyraził nadzieję, że spotkanie przyczyni się integracji absolwentów i przyjaciół Wydziału Prawa, Prawa Kanonicznego i Administracji KUL.
Przemówienie przewodniczącego Stowarzyszenia Absolwentów i Przyjaciół Wydziału Prawa KUL podczas zebrania absolwentów WPPKiA w dniu 23 czerwca 2010 r.
Authors: Krukowski Józef
Published: September 2023

Bardzo serdecznie dziękuję organizatorom za zaproszenie na dzisiejsze spotkanie. Korzystając z tej okazji, pragnę Państwa poinformować o istnieniu „Stowarzyszenia Absolwentów i Przyjaciół Wydziału Prawa Katolickiego Uniwersytetu Lubelskiego”, jego powstaniu, celach i zamierzeniach na najbliższą przyszłość.
Sprawozdanie z I Ogólnopolskiego Konkursu Prawa Kanonicznego
Authors: Zając Paweł
Published: September 2023

Dnia 23 marca 2011 r. w Auli Jana Pawła II Uniwersytetu Kardynała Stefana Wyszyńskiego w Warszawie odbył się finał I Ogólnopolskiego Konkursu Prawa Kanonicznego. Organizatorami Konkursu byli: Koło Naukowe Cywilistów, Koło Naukowe Utriusque Iuris oraz Wydział Prawa Kanonicznego UKSW w Warszawie.
Praktyczne aspekty regulacji postępowania dotyczącego przymusowego leczenia alkoholików w świetle proponowanych zmian
Authors: Studzińska Joanna
Published: September 2023

Według Ministerstwa Sprawiedliwości obecne przepisy stwarzające sądowi możliwość orzekania przymusowego leczenia alkoholików nie spełniają należycie swej roli ze względu na brak efektywności wykonywania orzeczeń wydanych przez sądy. Niewątpliwie jedną z przyczyn takiego stanu rzeczy jest brak dobrowolności odbycia takiego leczenia przez osobę, której dotyczy postępowanie oraz brak konsekwencji w prowadzonym postępowaniu. Istotne jest zatem zbadanie obowiązującej procedury i kierunków proponowanych zmian ustawy z dnia 26 października 1982 r. o wychowaniu w trzeźwości i przeciwdziałaniu alkoholizmowi, a zwłaszcza problemów faktycznych w zakresie postępowania sądowego i efektywności postępowania, a także dalszej celowości jego utrzymania w wyżej wskazanej ustawie.
Research on consumer negative comment behavior based on social support on social commerce platforms
Authors: Wang Ru , Peng Kexin , Liu Fang , Li Shugang
Published: September 2023

With the increasing of online social behavior, social relationships have an important impact on consumer negative comment behavior (CNCB) on social commerce platforms. Existing studies lack to describe CNCB influenced by social relationships on social commerce platforms from the perspective of well-thought-out planning results, and the proposed structural equation models in previous studies have been difficult to predict CNCB. Hence, this study proposes a new structural equation model (SEM) and artificial neural network (ANN) model to deeply explore and reveal the generation mechanism of CNCB in the context of social commerce platforms based on the theory of planned behavior (TPB). We regard social support as a moderating effect and construct a consumer negative comment planning behavior model (CNCPBM). The results of the data analysis show CNCPBM is supported. This study provides an important theoretical and practical contribution to CNCB, and offers practical management enlightenment for the managers of social commerce platforms.