bluuebunny/crossref_metadata_2025 huggingface dataset:
RESEARCH OF ORGANOLEPTIC PARAMETERS OF DUTCH CHEESE, PRODUCED FROM MILK OF COWS OF DIFFERENT BREEDS
Authors: Nazarenko Yuliya , Ladyka Volodymyr , Opara Victor , Pavlenko Yuliia
Published: February 2019

The aim of this research is to study an influence of types of different breeds of milk cows on organoleptic properties of Dutch cheese at different rations of their food. It allows to receive cheese with prognosticated quality characteristics and to manage marketing strategies at cheese realization.

The work presents the results of studying organoleptic properties of Dutch cheese, produced of milk of cows of different breeds, traditionally bred in the Northern-Eastern region of Ukraine.

For studying an influence of cows feeding on exclusive properties of hard cheese, traditional food rations of cows were added with forages of a silage-hay type with Lucerne as a main source of proteins (44 % of the daily norm). Rations were practically identical with traditional ones by the content of energy and main food value factors and in general corresponded to norms of cows feeding. It has been demonstrated, that the high mark of cheese, up to 45 points for the taste and smell and total point mark 99 of 100 possible was obtained as a result of changing food rations at the expanse of introducing Lucerne silage in them. The data on optimization of food rations of certain cow breeds allow managing quality characteristics of milk and products of and are expedient for making cheese with unique regional characteristics.

At conducting the comparative organoleptic assessment, there has been revealed a distinct dependence between a point mark of quality parameters of cheese on a breed of milk cows, and also on food rations of them. At the silage-hay food ration of animals, the received Dutch cheese had higher quality characteristics after 60 days of storage than cheese samples, obtained of cow milk at the traditional food ration.
Research of crypto-code designs construction for using in post quantum cryptography
Authors: Yevseiev Serhii , Gavrilova Alla , Tomashevsky Bogdan , Samadov Firuz
Published: February 2019

The article analyzes construction of crypto-code designs (CCDs) on the basis of asymmetric Mac-Alice and Niederreiter crypto-code systems on elliptical (EC) and modified elliptic codes (MEC), which, in the conditions of post-quantum cryptography, allow to provide a guaranteed level of crypto stability, to counteract the modern Attacks and attack by V. Sidelnikov on the theoretical code schemes of McAlias and Niederreiter. Schemes of hybrid crypto-code designs constraction the lossy codes are addressed. Methods of constructing mechanisms of confidentiality and integrity of banking information resources under hybrid threats to security components (information security, cybersecurity, information security) are proposed. Using of a lossy code is suggested to this end. Lossy Code allow you to increase the speed of code changes by reducing the power of the field when causing damage to open text and reducing the amount of data transferred by causing harm to the cipher text. The methods of constructing unprofitable codes and approaches for use in hybrid KKK of McAlias and Niederreiter on modified elliptic codes are considered. Practical algorithms for the use of the MV2 mechanism in McAlias’ CCD and Niederreiter’s modified elliptic codes are proposed, which allows the implementation of the CCD hybrid scheme. The comparative results of the study of stability and power capacity with respect to their practical use in automated banking systems are presented.
Adolescent Pregnancy’s Ongoing Effects on the Depression and Anxiety Scores in Subsequent Pregnancy
Authors: Turkyilmaz Esengul , Hesapcioglu Selma Tural
Published: February 2019

Objective: Child/adolescent 'marriages' and following pregnancies have adverse effects both on the child and adolescent mother.The aim of this study is to detect whether the adult pregnant women who have previous adolescent pregnancy more susceptible to the depression and anxiety than current adolescent pregnants and the adult pregnant women who have no adolescent pregnancy history. Study Design: This cross sectional study evaluated a total of 163 pregnant women who attended to our antenatal clinic. Subjects aged between 16 and 43 years including both adolescent and adult pregnant women were divided into three groups. These groups are current adolescent pregnant women (Group I), adult pregnant women who have adolescent pregnancy history (Group II), adult pregnant women who have no adolescent pregnancy history (Group III). Three groups were compared in terms of the pregnancy status, socio-demographic variables and depression-anxiety scores.Result: In the current study the highest depression and anxiety scores were observed in Group II [depression scores’ median (IQR) values respectively 5 (8.5) points for Group I, 12.5 (8.5) for Group II, 9 (12) for Group III (p<0.001 between Group I and Group II for BDI comparison). Anxiety scores’ median (IQR) values respectively 19.5 (15.5) for group II, 9 (15.5) for group I, 14 (15.25) for Group III (p=0.005 between Group I and Group II for BAI comparison). Conclusion: Marriage and pregnancy at an early age are considered as risk factors for psychiatric morbidity in the next pregnancy. Therefore, women with a history of teenage pregnancy should be carefully monitored for depression and anxiety symptoms.
Study the dynamics of hollow jet formation under vapor outflow from the supercritical state
Authors: Bolotnova R.Kh.
Published: February 2019

The features of the unsteady process of a cavity formation inside the jet at a sudden outflow of water vapor through a thin nozzle from a pressure vessel, initially in a supercritical state, are studied. A numerical study was carried out by using the sonicFoam solver of the OpenFOAM library with the Peng-Robinson equation of state in a two-dimensional axisymmetric approximation. Visualization of the obtained solutions is presented in the form of pictures dynamics for fields of velocities and temperatures. It is shown that the mode of formation and maintenance of the cavity inside the jet is supported more than 100 μs from the beginning of the expiration process.
The study of acoustic scattering from a single sound-permeable sphere
Authors: Nasibullaeva E.Sh.
Published: February 2019

The paper presents a generalized mathematical model and numerical investigation of the problem of acoustic scattering from a single sound-permeable sphere during the passage of two types of waves - spherical from a monopole radiation source and a plane one. In solving the Helmholtz equation, a numerical technique based on the fast method of multipoles is used, which allows achieving high accuracy of the results obtained at the lowest cost of computer time. The calculations are compared with known experimental data and a good agreement is obtained. The formulas for calculating the main characteristic of the scattering field (the total scattering cross section) for a sound-permeable sphere are generalized. The effect on this characteristic of the physical parameters of media outside and inside the sphere, such as the density and speed of sound, is shown. A numerical parametric analysis of the pressure distribution around a single sound-permeable sphere for different values of the wave radius, density, and speed of sound of the outer and inner medium of the sphere is carried out. The obtained results will later be used for test verification calculations for the numerical solution of the generalized problem of acoustic scattering of a set of sound-permeable spheres (coaxial or arbitrarily located in space).
Melting of ice in a porous medium saturated with ice and gas while injecting warm water
Authors: Shagapov V.Sh. , Zapivakhina M.N.
Published: February 2019

The numerical models for the injection of warm water (in the temperature range from 300 to 340 K) into a cold porous formation are considered. Simplified models describing the processes of heat and mass transfer are proposed. The influence of the parameters determining the initial state of the porous medium, the boundary pressure, temperature and moisture content on the rate of propagation of hydrodynamic and temperature fields in the porous medium is investigated. It has been established that it is economically feasible to melt frozen soils saturated with ice and gas (air) at a sufficiently low temperature of the injected water (about 300 K).
Numerical simulation of single vapor bubble dynamics in a liquid in an intense acoustic field
Authors: Davletshin A.I , Khalitova T.F.
Published: February 2019

The possibility of increasing the calculation efficiency by the joint use of two models of the dynamics of a single weakly-nonspherical vapor bubble under its strong collapse in liquid is studied. In both models the motion of liquid and vapor is split into a spherical component and its small nonspherical perturbation. The models differ in the description of the spherical component. In the first (simplified) model, it is described by a system of ODE together with partial differential equations in temperature, derived under the assumption of weak compressibility of liquid and bubble homobaricity. In the second model, one-dimensional gas dynamics equations are applied. The advantage of the simplified model consists in determining a numerical solution with much-less computer time costs in comparison with what is required for the numerical integration of gas dynamics equations. The assumptions used in the simplified model in the final stage of collapse become incorrect, and, as a result, the numerical solution errors increase. Therefore, the simplified model is applied at the beginning of bubble collapse, whereas the gas dynamics equations are used at its end. Within this approach, the numerical solution in the final stage of collapse is dependent on the moment of transition to the gas dynamics equations. It is shown that satisfactory description of evolution of bubble sphericity distortion is achieved when the transition is made under the condition that the Mach number M of vapor in the vicinity of the bubble surface is less than 0.4. Satisfactory resolution of the shock wave in the bubble is attained when the transition is performed at M<0.2.
Features of spatial shock-wave flows in vapor-gas-liquid mixtures
Authors: Bolotnova R.Kh. , Agisheva U.O. , Buzina V.A.
Published: February 2019

The two-phase model of vapor-gas-liquid medium in axisymmetric two-dimensional formulation, taking into account vaporization is constructed. The nonstationary processes of boiling vapor-water mixture outflow from high-pressure vessels as a result of depressurization are studied. The problems of shock waves action on filled by gas-liquid mixture volumes are solved.
The technique for reconciling the dynamic characteristics of gas turbine engines and fuel automatics
Authors: Denisova E.V. , Chernikova M.A.
Published: February 2019

The paper presents the technique for matching the dynamic characteristics of gas turbine engines and fuel systems for the unhuman vehicle, described by its logic and graphically illustrates the relationship of the dynamic characteristics of the gas turbine engine, the acceleration path, depending on the frequency of the rotor of the turbocharger rotation time and, depending on the fuel consumption speed.
Free convection of vertically stratified fluid in 2D cell
Authors: Moiseyev K.V. , Khizbullina S.F. , Bakhtizin R.N.
Published: February 2019

The paper deals with the free-convection of Rayleigh-Berard of a Newtonian fluid with allowance for vertical stratification in 2D cell. A closed mathematical model of free convection of an inhomogeneous fluid is suggested under the assumption of a linear dependence of the liquid density on temperature, impurity concentration and salinity. It is shown numerically that the initial inhomogeneity of the liquid, in particular the density along the height, leads to complication of the process of free convection in the form of formation of layered structures.
Modeling of Dynamic Loads on the Polished Rod of Pumping Unit in Case of Mulfunction of Rod Pump Operating
Authors: Topolnikov A.S.
Published: February 2019

The paper presents the results of theoretical modeling of joined movement of pump rods and plunger pump and multiphase flow in a well for determination of dynamic loads on the polished rod of pumping unit. The specificity of the proposed model is the possibility of taking into account for complications in rod pump operating, such as leakage in valve steam, presence of gas and emulsion, incorrect fitting of plunger inside the cylinder pump. The satisfactory agreement of results of the model simulation with filed measurements are obtained.
O metal, suas especificidades e desdobramentos
Authors: Carvalheiro Marcus , Rauen Moraes Taiza Mara
Published: February 2019

Este artigo objetiva apresentar os desdobramentos do metal como estilomusical advindo do rock, que a partir dos anos 1980, identifi cado como heavy metal, se tornou um gênero musical difundido mundialmente. Questiona-se o processo de atribuição de valores, assim como quais são as disputas pelo espaço urbano envolvidas nesse desenvolvimento e qual é a perspectiva do cenário atual. Os conceitos acionados para a discussão foram a teoria dos gêneros musicais, de Franco Fabbri (1980), e a concepção de subcultura, de Andy Bennet (2002), e a abordagem da relação midiática com a música foi sustentada pelas refl exões de Jeder Janotti Junior (2015).
A família rural do Piraí, políticas públicas e patrimônio cultural
Authors: Tavares Vieira Filho Adhemar , Areas Patricia De Oliveira
Published: February 2019

A proposta deste artigo é demonstrar e analisar a relação existente entreo patrimônio cultural rural mantido e praticado pela família rural da região do Piraí, em Joinville (SC), e como as políticas públicas rurais e suas atividades podem impactar esse patrimônio cultural, tanto positiva como negativamente. Empregaram-se como metodologia a pesquisa bibliográfi ca e entrevistas semiestruturadas com técnicos e gestores da Fundação de Desenvolvimento Rural 25 de Julho do município de Joinville (responsável pelas referidas políticas à época das entrevistas) e com pessoas das famílias rurais da região do Piraí. Busca-se demonstrar que políticas públicas bem empregadas podem ser ferramentas de sustentabilidade de preservação do patrimônio cultural.
Finitude como poética
Authors: Lamas Nadja De Carvalho
Published: February 2019

Este texto busca compreender a poética contemporânea por meio da análiseda proposição artística de Mark Formanek, apresentada na 11.ª Bienal do Mercosul, em Porto Alegre. Tal proposta rompe com a materialidade, pois a efemeridade lhe é inerente. Standard time, assim como outras produções artísticas contemporâneas, tenciona o sistema da arte, pois tem a fi nitude como parte de sua poética, proposição que evidencia o quão complexo é o mundo da arte e as problemáticas artísticas contemporâneas.
Desgaste e armazenamento das escovas dentais numa unidade oncológica infantil Dental brush wear and storage in a child oncological unit
Authors: Marin Constanza , Michels Bruna
Published: February 2019

Introdução: A escova dental constitui o meio mais eficaz e popularizado de controle da placa bacteriana, porém pode se tornar um veículo de disseminação de microrganismos, especialmente em pacientes imunocomprometidos. Objetivo: Avaliar o desgaste e a forma de armazenamento das escovas dentais de pacientes internados no setor de oncologia de um hospital infantil do norte catarinense. Material e métodos: A pesquisa foi realizada com 30 pacientes entre 0 e 17 anos. Aplicou-se um questionário para os pais ou responsáveis legais a fim de identificar a situação socioeconômica, limpeza da escova e forma de armazenamento. As escovas foram analisadas e classificadas de acordo com o grau de desgaste das cerdas, grau de limpeza e umidade. Resultados: Grande parte dos pacientes também relatou ter complicações bucais durante a internação e tratamento oncológico (63%). Dos pacientes visitados, 27% não possuíam escova dental no momento da entrevista. Quanto às escovas analisadas, 73% estavam com grau de desgaste das cerdas em condições adequadas para uso, enquanto 27% estavam em condições inadequadas. De acordo com o grau de limpeza das escovas, 36% apresentavam restos de alimento, dentifrício ou fungo. As escovas eram armazenadas de diversas formas dentro do hospital, e a maioria foi encontrada na gaveta sem nenhuma proteção (27%). Conclusão: Há necessidade de promover maior orientação aos pacientes oncológicos quanto à troca, higienização e ao armazenamento das escovas dentais.
Tratamento de trauma oclusal anterior com pino de fibra de vidro associado à coroa de dissilicato de lítio Anterior occlusal trauma treatment with fiberglass pin associated to lithium disilicate crown
Authors: Hintz Raisa Carolina , Saab Rafaela Caramori , Garcia Eugenio , Hilgenberg Sergio Paulo , Cunha Leonardo Fernandes da , Deliberador Tatiana Miranda , Gonzaga Carla Castiglia
Published: February 2019

Introdução: A aparência estética é uma das preocupações do ser humano, o que leva a uma busca constante por uma estética que expresse harmonia, naturalidade e expressividade. Sendo assim, os procedimentos restauradores têm contribuído positivamente para a resolução dos desafios odontológicos estéticos. Objetivo e relato de caso: Relatar um caso clínico com associação de clareamento dental, confecção de pino intrarradicular e coroa indireta em dissilicato de lítio em que foi devolvida ao paciente a estética desejada. Pacientede 23 anos de idade fraturou o incisivo central superior direito na infância; insatisfeito com a instabilidade de cor do dente, buscou novas alternativas de tratamento. Conclusão: A associação de diferentes tratamentos na Odontologia estética pode apresentar resultados satisfatórios para o restabelecimento estético e funcional de dentes anteriores.Introduction: The aesthetic appearance is one of the human being concerns, leading to constant search for an aesthetic that expresses harmony, naturalness and expressiveness. So, the restorative procedures have contributed positively to overcome the aesthetic dentistry challenges. Objective and case report: Report a clinical case in association to dental whitening, making of intraradicular pin and indirect crown of lithium disilicate when it was returned to the patient the desired aesthetic. A 23 years old patient fractured the right central incisor in the childhood, dissatisfied with the tooth color instability, he looked for new treatment alternatives. Conclusion: The association of different treatments in the aesthetic dentistry might present satisfactory results to the aesthetic and functional reestablishment of anterior teeth.
Progress of Individualized Chemotherapy for Gastric Carcinoma Under the Guidance of Genetic Testing
Authors: Jin Xin , Jiang Meng-lin , Wu Zhao-Hui , Fan Yu
Published: February 2019

Background:

Gastric cancer is a major malignancy that has high incidence rates worldwide. Approximately 30% of patients with gastric cancer have progressed into advanced stages at the time of diagnosis. Chemotherapy is the standard-of-care for most advanced gastric cancer and elicits variable responses among patients. Personalized chemotherapy based on genetic information of individual patients with gastric cancer has gained increasing attention among oncologists for guiding chemotherapeutic regimens.

Methods:

This review summarizes recent progress of individualized chemotherapy in gastric cancer guided by pharmacogenomics. Variable medical research search engines, such as PubMed, Google Scholar, SpringerLink and ScienceDirect, were used to retrieve related literature. Only peerreviewed journal articles were selected for further analyses.

Results and Conclusion:

The efficiency of chemotherapy in patients with gastric cancer is not only determined by chemotherapeutic drugs but is also directly and indirectly influenced by functionally correlative genes. Individual gene alteration or polymorphism remarkably affects patients’ responses to particular chemotherapy. Most studies have focused on the influence of single-gene alteration on a selected drug, and only a few works explored the interaction between therapeutics and a panel of genes. Individualized chemotherapy regimens guided by a genetic survey of a multiple-gene panel are expected to remarkably improve the treatment efficacy in patients with advanced gastric cancer and may become the new standard for personalizing chemotherapy for gastric cancer in the near future.
The Clinical Prognostic Value of LRG1 in Esophageal Squamous Cell Carcinoma
Authors: Wang Yuanyuan , Xing Qian , Chen Xue , Wang Jianbo , Guan Shanghui , Chen Xuan , Sun Peng , Wang Mingxia , Cheng Yufeng
Published: February 2019

Background:

Leucine-rich-alpha-2-glycoprotein1 (LRG1) is a new oncogene-related gene, which has been proven important for the development and poor prognosis of human cancers. However, whether it participates in esophageal squamous cell carcinoma (ESCC) progression remains unclear.

Objective:

To investigate the expression level and functional influence of LRG1 in ESCC.

Methods:

The expression of LRG1 was evaluated on the mRNA and protein level in ESCC patients. Then, correlation of LRG1 expression with clinicpathological variables was analyzed in ESCC. Besides, to clarify the biological function of LRG1, Eca109 and KYSE150 cells were transfected with LRG1 shRNA, the cell viability, clonal efficiency, apoptosis and invasion assays in vitro were performed.

Results:

LRG1 was significantly over-expressed in ESCC and related to deeper invasion depth (T stage) and distal metastasis (M stage). Kaplan-Meier analysis indicated that LRG1 up-regulation in ESCC was closely correlated to worse clinical survival (overall survival and progression-free survival), all P<0.001. LRG1 was confirmed to be an independent poor premonitory indicator for clinical outcomes in ESCC through the univariate and multivariate analyses. Down-regulation of LRG1 in ESCC cells markedly suppressed cell proliferation and invasion, stimulated apoptosis (all p <0.01).

Conclusion:

LRG1 might play a significant role in the progression of ESCC, and could be served as a promising prognostic prediction for ESCC patients.
Detection and Analysis of RNAs Expression Profile for Methylated Candidate Tumor Suppressor Genes in Nasopharyngeal Carcinoma
Authors: Zhao Shuang , Zhang Ye , Liang Xujun , Li Maoyu , Peng Fang , Chen Zhuchu , Chen Yongheng
Published: February 2019

Background:

DNA methylation, which acts as an expression regulator for multiple Tumor Suppressor Genes (TSGs), is believed to play an important role in Nasopharyngeal Carcinoma (NPC) development.

Methods:

We compared the effects of 5-aza-2-deoxycytidine (decitabine, DAC) on gene expression using RNA sequencing in NPC cells.

Results:

We analyzed Differentially Expressed Genes (DEGs) in NPC cells using DAC demethylation treatment and found that 2182 genes were significantly upregulated (≥ 2-fold change), suggesting that they may play a key role in cell growth, proliferation, development, and death. For data analysis, we used the Gene Ontology database and pathway enrichment analysis of the DEGs to discover differential patterns of DNA methylation associated with changes in gene expression. Furthermore, we evaluated 74 methylated candidate TSGs from the DEGs in NPC cells and summarized these genes in several important signaling pathways frequently disrupted by promoter methylation in NPC tumorigenesis.

Conclusion:

Our study analyzes the DEGs and identifies a set of genes whose promoter methylation in NPC cells is reversed by DAC. These genes are potential substrates of DNMT inhibitors and may serve as tumor suppressors in NPC cells.
Peptide Receptor Radionuclide Therapy for Pancreatic Neuroendocrine Tumours
Authors: Alsadik Shahad , Yusuf Siraj , AL-Nahhas Adil
Published: February 2019

Background:

The incidence of pancreatic Neuroendocrine Tumours (pNETs) has increased
considerably in the last few decades. The characteristic features of this tumour and the development of
new investigative and therapeutic methods had a great impact on its management.

Objective:

The aim of this review is to investigate the outcome of Peptide Receptor Radionuclide Therapy
(PRRT) in the treatment of pancreatic neuroendocrine tumours.

Methods:

A comprehensive literature search strategy was used based on two databases (SCOPUS, and
PubMed). We considered all studies published in English, evaluating the use of PRRT (177Luteciuim-
DOTA-conjugated peptides and 90Yetrium- DOTA- conjugated peptides) in the treatment of pancreatic
neuroendocrine tumours as a standalone entity or as a subgroup within the wider category of Gastroenteropancreatic
Neuroendocrine Tumours (GEP NETs).

Results:

PRRT was found to be an effective treatment modality as a monotherapy or in combination
with other therapies in the treatment of non-operable and metastatic pNETs where other options are
limited. Complete response was reported to be between 2-6% while partial response was achieved in up
to 60% of cases. Survival analysis was also impressive. Progression Free Survival (PFS) reached a mean
of 34 months and Overall Survival (OS) of 53 months. PRRT also proved to improve patients’ Quality
of Life (QoL). Acute and sub-acute side effects like nephrotoxicity and haematotoxicity are usually mild
and reversible.

Conclusion:

PRRT is well tolerated and effective treatment option for non-operable and/or metastatic
pNETs. Side effects are usually mild and reversible. Larger randomized controlled trails need to be done
to compare PRRT with other treatment modalities and to provide more detailed guidelines regarding
patient selections, the choice of PRRT, follow up and response assessment to maximum potential benefit.
An eHealth tool to prepare a first orthopedic consultations: a use and usability study (Preprint)
Authors: Claassen Aniek A.O.M. , Vliet Vlieland Thea P.M. , Busch Vincent J.J.F. , Schers Henk J. , van den Hoogen Frank H.J. , van den Ende Cornelia H.M.
Published: February 2019

BACKGROUND

The use of eHealth technology to prepare first orthopedic consultations for patients with hip or knee osteoarthritis seems promising. Exploration of data on use and usability of an educational eHealth tool can reveal potential modifications that may increase engagement and effectiveness.

OBJECTIVE

1) to identify use and usability of a standalone educational eHealth tool for patients with suspected hip or knee osteoarthritis (OA), 2) to explore if recorded questions in the eHealth tool were in line with an existing widely used question prompt list, and 3) to investigate if user characteristics are related to use and usability.

METHODS

We used data of 144 patients who used the educational eHealth tool to prepare an upcoming first orthopaedic consultation. We defined ‘users’ and ‘non-users’ based on opening the tool at least once or not. ‘Users’ were specified as ‘active’ and ‘passive’. Recorded questions in preparation for the upcoming consultation were categorized into themes fitting 3 predefined questions: ‘What are my options?’, ‘What are the possible benefits and harms of those options?’ and ‘How likely are each of the benefits and harms to happen to me?’, or in a ‘remaining’ category. Usability was measured using the System Usability Scale (SUS, 0-100). We collected data on demographic and clinical characteristics, knowledge on OA, and internet and smartphone usage in daily life. Characteristics associated with ‘users’ and ‘non-users’ were analysed using multivariable logistic regression analysis.

RESULTS

A total of 116 (81%) participants used the educational eHealth tool, of whom 87 (75%) were ‘active users’. Out of 3 components (‘Information’, ‘My consultation’ and ‘Medication), ‘Medication’ was least used (34%). Based on the recorded questions of users a fourth predefined question could be proposed, i.e. “What is my situation at this moment?”. Mean (SD) SUS score was 64.8 (16.0). No difference was found in SUS scores between superficial and active users (mean difference (95% CI): 0.04 (-7.69, 7.77)). Participants with higher baseline knowledge on OA (OR (95% CI): 1.2 (1.0, 1.4)), who used the internet less frequent in daily life (OR (95% CI): 0.6 (0.5, 0.9)) were more likely to use the educational eHealth tool. We found no differences in demographic and clinical characteristics between superficial and active users.

CONCLUSIONS

Based on the results of this study it can be concluded that the use of an educational eHealth tool to prepare a first orthopedic consultation in patients with hip and knee OA is feasible. Results provide points for improvements to the content of the tool to improve usability. No clear practical implications were found in this study to support implementation of the educational eHealth tool in specific subgroups.

CLINICALTRIAL

Dutch Trial Register NTR6262
Privacy-Preserving Methods for Feature Engineering Using Blockchain: Review, Evaluation, and Proof of Concept (Preprint)
Authors: Jones Michael , Johnson Matthew , Shervey Mark , Dudley Joel T , Zimmerman Noah
Published: February 2019

BACKGROUND

The protection of private data is a key responsibility for research studies that collect identifiable information from study participants. Limiting the scope of data collection and preventing secondary use of the data are effective strategies for managing these risks. An ideal framework for data collection would incorporate feature engineering, a process where secondary features are derived from sensitive raw data in a secure environment without a trusted third party.

OBJECTIVE

This study aimed to compare current approaches based on how they maintain data privacy and the practicality of their implementations. These approaches include traditional approaches that rely on trusted third parties, and cryptographic, secure hardware, and blockchain-based techniques.

METHODS

A set of properties were defined for evaluating each approach. A qualitative comparison was presented based on these properties. The evaluation of each approach was framed with a use case of sharing geolocation data for biomedical research.

RESULTS

We found that approaches that rely on a trusted third party for preserving participant privacy do not provide sufficiently strong guarantees that sensitive data will not be exposed in modern data ecosystems. Cryptographic techniques incorporate strong privacy-preserving paradigms but are appropriate only for select use cases or are currently limited because of computational complexity. Blockchain smart contracts alone are insufficient to provide data privacy because transactional data are public. Trusted execution environments (TEEs) may have hardware vulnerabilities and lack visibility into how data are processed. Hybrid approaches combining blockchain and cryptographic techniques or blockchain and TEEs provide promising frameworks for privacy preservation. For reference, we provide a software implementation where users can privately share features of their geolocation data using the hybrid approach combining blockchain with TEEs as a supplement.

CONCLUSIONS

Blockchain technology and smart contracts enable the development of new privacy-preserving feature engineering methods by obviating dependence on trusted parties and providing immutable, auditable data processing workflows. The overlap between blockchain and cryptographic techniques or blockchain and secure hardware technologies are promising fields for addressing important data privacy needs. Hybrid blockchain and TEE frameworks currently provide practical tools for implementing experimental privacy-preserving applications.
Probiotic (Lactobacillus casei) Encapsulation Using the Method of Spray Drying with Combined Prebiotic from Iles-Iles (Amorphopallus oncophyllus) and Protectant Agent (Skim Milk, Gum Arabic, Maltodextrin)
Authors: Cahya Aloysius Prima , Syaflan Meidi , Ngatirah Ngatirah
Published: February 2019

The aims of this research were to know the effect of combine iles-iles (refined starch, whole iles-iles flour, and refined glucomannan) as encapsulating agent (capsule materials) and different protectant agents to get microcapsule synbiotic, which have the highest number of probiotic cells and high viability against low pH and bile salt. Design blocks complete with factorial design was used in the experimental design. The first factor was capsule materials with a concentration of 10% consisting of three material types: A1 (refined glucomannan), A2 (refined starch), and A3 (Iles-iles native). The second factor was protectant, protecting the probiotic bacteria during spray drying, used at concentration of 5% consisting of three substances i.e. B1 (skim milk), B2 (maltodextrin), and B3 (gum arabic). Using protectant agents on the MRS for the growth of L. casei resulted no effects against the numbers of LAB (lactic acid bacteria), density, moisture content, and hygroscopicity; however, it had influence on yield and solubility. The best use based on the reduction of LAB numbers were flour and gum Arabic which was significant compared to other fractions.Keywords: iles-iles, glucomannan, starch, protectant agent, symbiotic LAB
Determining Optimal Architecture of CNN using Genetic Algorithm for Vehicle Classification System
Authors: Wahyono Wahyono , Hariyono Joko
Published: February 2019

Convolutional neural network is a machine learning that provides a good accura-cy for many problems in the field of computer vision, such as segmentation, de-tection, recognition, as well as classification systems. However, the results and performance of the system are affected by the CNN architecture. In this paper, we propose the utilization of evolutionary computation using genetic algorithm to de-termine the optimal architecture for CNN with transfer learning strategy from parent network. Furthermore, the optimal CNN produced is used as a model for the case of the vehicle type classification system. To evaluate the effectiveness of the utilization of evolutionary computing to CNN, the experiment will be conducted using vehicle classification datasets.
Genetic Algorithm for lecturing schedule optimization
Authors: Kristiadi David , Hartanto Rudy
Published: February 2019

Scheduling is a classic problem in lecturing. Rooms, lecturers, times and scheduling constraints must be managed well to get an optimal schedule. University of Boyolali (UBY) also encounter the same scheduling problems. The problem was tried to be solved by building a library based on Genetic Algorithm (GA). GA is a computation method which inspired by natural selection. The computation consists of some operators i.e. Tournament Selection, Uniform Crossover, Weak Parent Replacement and two mutation operators (Interchanging Mutation and Violated Directed Mutation (VDM)). The two mutation method are compared to find which better mutation operator. The library was planned to have a capability to define custom constraints (scheduling requirements that were not accommodated by the library) without core program modifications. The test results show that VDM is more promising for optimal solutions than Interchanging Mutation. In UBY cases, optimal solution (fitness value=1) is reached in 12 minutes 41 second with adding 6 new room and inactivated 2 constraint i.e. lecturing begins at 14.00 except for 3rd semester of science law study program with morning class and lecturing participants must not over classroom capacity.
Apps-based Machine Translation on Smart Media Devices - A Review
Authors: Gunarto Hary
Published: February 2019

Machine Translation Systems are part of Natural Language Processing (NLP) that makes communication possible among people using their own native language through computer and smart media devices. This paper describes recent progress in language dictionaries and machine translation commonly used for communications and social interaction among people or Internet users worldwide who speak different languages. Problems of accuracy and quality related to computer translation systems encountered in web & Apps-based translation are described and discussed. Possible programming solutions to the problems are also put forward to create software tools that are able to analyze and synthesize language intelligently based on semantic representation of sentences and phrases. Challenges and problems on Apps-based machine translation on smart devices towards AI, NLP, smart learning and understanding still remain until now, and need to be addressed and solved through collaboration between computational linguists and computer scientists.
Pedagogias decoloniais em lócus subalternos: relações étnico-raciais e o ensino de História
Authors: Almeida Mirianne Santos de , Mesquita Ilka Miglio de , Oliveira Valéria Maria Santana
Published: February 2019

A partir das lentes decoloniais, construímos este texto com o fito de analisar práticas educativas produzidas em espaços sergipanos historicamente marginalizados – a tribo indígena Xokó e a Comunidade Remanescente de Quilombo Maloca – e, a partir deles, pensar e problematizar o ensino de História. Tomamos o fazer etnográfico como caminho metodológico e construímos o arcabouço teórico a partir dos estudos empreendidos por Mignolo (2005), Quijano (2005) e Walsh (2013), que nos oferecem ferramentas conceituais para vislumbrar possibilidades no ensino de História no Brasil que transcendam a historiografia conhecida como tradicional – produções nas quais, por tanto tempo, se estabeleceu uma educação colonizadora, imposta sob a perspectiva eurocêntrica – e, numa perspectiva decolonial, reverberem na compreensão dos povos originários, também, como protagonistas.
O improvável na aula de História: sociabilidades, racialidades e modos de estar junto na escola
Authors: Meinerz Carla Beatriz , Caimi Flávia Eloisa , Oliveira Sandra Regina Ferreira de
Published: February 2019

O artigo resulta de uma reflexão compartilhada no campo da Pesquisa em Educação e almeja interseccionar as categorias sociabilidade e racialidade na análise das relações estabelecidas nas instituições escolares. Enfoca a escola como espaço complexo de construção de modos de estar junto, ambiente marcado por uma ecologia de distintos saberes. O ensino de história, como lócus da instituição escolar, é abordado como lugar do improvável. Ao enfocar a aula de história, destacamos experiências que oscilam desde um possível compartilhamento das diferenças até a sua negação. Tal negação pode revelar situações e atores sociais ignorados ou trivializados em suas relações cotidianas. Propõe a análise de situações improváveis no cotidiano escolar como método diferenciado de análise investigativa. Os resultados parciais das pesquisas em questão se produzem no movimento de questionamento epistemológico e pedagógico provocado pelo pensamento decolonial.
Implicação da força do eurocentrismo no currículo de um curso de licenciatura em História: que espaço é reservado à história negra e indígena?
Authors: Da Silva José Bonifácio Alves
Published: February 2019

O artigo apresenta a implicação da força do eurocentrismo no espaço reservado às histórias das populações negras e indígenas no currículo de um curso de licenciatura em história de uma universidade pública do estado do Paraná. O projeto pedagógico do curso, observações em aulas das diferentes disciplinas e entrevistas com docentes e discentes trouxeram as questões que foram analisadas. Afetadas pela superiorização da brancura e pelo eurocentrismo, histórias indígenas e negras eram situadas como temáticas com menores relevâncias na formação de professores de história investigada, por causa do pouco espaço disponibilizado no currículo para o estudo dessas histórias. Entretanto, ocasionalmente, ocorrem algumas iniciativas de inserir debates a respeito da história negra e indígena, mas também, consequentemente, acerca das relações étnico-raciais pelas quais o currículo está atravessado.
Pregnant woman survives aortic dissection, dies later of coronary embolism - a unique case of a non-compliant patient
Authors: Preveden Andrej , Samardzija Golub , Susak Stamenko , Ilic Aleksandra , Redzek Aleksandar
Published: February 2019

Introduction. The incidence of aortic dissection ranges 3?5 cases per 100,000 person-years. In women under the age of 40 who acquire aortic dissection, almost half of the cases happen during pregnancy. Case outline. We report a case of a 22-year-old pregnant woman in the 16th gestational week with a history of arterial hypertension and known aortic dilatation, who was admitted with aortic dissection. She underwent the Bentall procedure, in which her aortic valve, ascending aorta, and proximal part of the aortic arch were replaced using valved composite graft. On the next day, the evacuation abortion was made, since the fetus didn?t survive the operation. Six years later, the patient stopped taking anticoagulation therapy and was admitted for prosthetic valve thrombosis, which was successfully treated with intravenous heparin. One year later, the patient died of a myocardial infarction due to coronary thromboembolism, confirmed on autopsy. Conclusion. Preconceptional counseling in women with a known aortic disease is of the utmost importance. Aortic dissection in pregnant women is an acute life-threatening condition for both mother and fetus that should be managed by a multidisciplinary team. After a mechanical heart valve implantation, lifetime oral anticoagulants are mandatory.
Nanoscale bubble study of cavitation inception on a platinum surface using molecular dynamics simulation
Authors: Fu Qiang , Li Mengyuan , Wang Xiuli , Yu Jianen , Zhu Rongsheng
Published: February 2019

The transient properties of liquid argon cavitation nuclei in platinum surface were studied by means of molecular dynamics simulation. The bubble nucleation, with a certain size and stability on the wall surface, was studied by different tensile distances and different wall wettabilities. Also the parameters of cavitation nuclei development, the system pressure, and the total pressure were analysed. The stability of cavitating nucleus growth is closely related to the metastable degree of the system and the wettability of the wall. The tensile distance of the wall surface has a critical value, and stretching greater than the critical value will induce a greater degree of instability in the system, which is conducive to the growth of the cavitation nucleus. A hydrophobic wall is more conducive to the growth of a cavitation nucleus, which is beneficial to spontaneous growth among cavitated nuclei, whereas a hydrophobic exerts has an inhibitory influence on cavitation nuclei.
A thermal model for open-rack mounted photovoltaic modules based on empirical correlations for natural and forced convection
Authors: Perovic Bojan , Klimenta Dardan , Jevtic Miroljub , Milovanovic Milos
Published: February 2019

This paper proposes a thermal model for calculating the temperature of open-rack mounted photovoltaic (PV) modules taking into account the meteorological conditions, position (i. e. the inclination of one PV module and the angle between its surface and wind direction) and technical characteristics of the PV modules. The present model is valid for the steady-state operation and is based on the energy balance equation in which the forced convection is modelled by the new empirical correlations. The possibility of occurrence of the flow separation along the surfaces of the PV modules is included in these correlations. The effect of the angle between the wind direction and the PV module plane, which is usually ignored in the modelling of forced convection, is also taken into consideration. In this manner, it is possible to estimate the temperature of PV modules more precisely, as well as to determine the power and efficiency which depend on the temperature. For four particular PV modules, it is found that the temperatures, obtained using the proposed thermal model, are in good agreement with the corresponding measured temperatures. Compared with the other models commonly used for thermal analysis of PV modules (SNL and NOCT-based correlations), this model yielded better results. The deviation of the PV module temperature calculated using the proposed thermal model from the measured one is up to 2?C, and the deviations of the PV module temperatures calculated using the SNL and NOCT-based correlations from the measured ones amount up to 5?C and 20?C, respectively, depending on the PV module type and ambient conditions.
The motion of a non-Newtonian nanofluid over a semi-infinite moving vertical plate through porous medium with heat and mass transfer
Authors: El-Dabe Nabil , Gabr Mahmoud , Elshekhipy Abd-Elhafez , Zaher Sameh
Published: February 2019

The motion of a non-Newtonian nanofluid over a semi-infinite moving vertical plate through porous medium stressed by an external uniform magnetic field with heat and mass transfer is investigated. The fluid under consideration obeys Eyring-Powell model. The effects of the physical parameters of the problem such as, permeability, chemical reaction as well as the fluid material parameters such as Hartmann number, Eckert number, and Reynolds number are discussed. The effects of external cooling (Gr > 0) of the plate by the free convection are considered. Graphical results are presented to highlight effects of various emerging parameters on velocity, temperature and concentration profiles.
Numerical study for heat transfer enhancement using CuO water nanofluids through mini-channel heat sinks for microprocessor cooling
Authors: Anwar Muhammad , Tariq Hussain , Shoukat Ahmad , Ali Hafiz , Ali Hassan
Published: February 2019

Water cooled heat sinks are becoming popular due to increased heat generation inside the microprocessor. Timely heat removal from microprocessor is the key factor for better performance and long life. Heat transfer enhancement is reached either by increasing the surface area density and/or by altering the base fluid properties. Nanoparticles emerge as a strong candidate to increase the thermal conductivity of base fluids. In this research, the thermal performance of mini-channel heat sinks for different fin spacing (0.2 mm, 0.5 mm, 1 mm, and 1.5 mm) was investigated numerically using CuO-water nanofluids with volumetric concentration of 1.5%. The numerical values computed were than compared with the literature and a close agreement is achieved. We recorded the minimum base temperature of chip to be 36.8?C for 0.2 mm fin spacing heat sink. A reduction of 9.1% in base temperature was noticed using CuO-water nanofluids for 0.2 mm fin spacing as compared to previously experimental estimated value using water [1]. The drop percentage difference in pressure between water and CuO-water nanofluids was 2.2-13.1% for various fin spacing heat sinks. The percentage difference in thermal resistance between water and CuO-water nanofluids was computed 12.1% at maximum flow rate. We also observed uniform temperature distribution for all heat sinks.
Determinants of Timely Adoption of the 2013 COSO Integrated Framework
Authors: Addy Noel D. , Berglund Nathan R.
Published: February 2019

In 2013, the Committee of Sponsoring Organizations of the Treadway Commission (COSO) released an updated version of its widely utilized Internal Control—Integrated Framework. The update responded to two decades of changes in the business environment and increased focus on technology in business operations and reporting. While the old framework is no longer supported by COSO (effective December 15, 2014), some SEC filers continued to utilize the old framework past its phase-out date. This placed such companies at increased risk for internal control failure compared to other companies and SEC scrutiny. We examine determinants of timely adoption of the 2013 COSO framework update. We find evidence that timely adoption is related to absence of reported internal control weaknesses, auditing firms, and interlocking directorates. Our study contributes to literature on how social networks and operational characteristics affect internal control governance decisions.