bluuebunny/crossref_metadata_2025 huggingface dataset:
Health Goal Attainment of Patients With Chronic Diseases in Web-Based Patient Communities: Content and Survival Analysis
Authors: Song Jiahe , Xu Pei , Paradice David B
Published: July 2020

Background

Activities directed at attaining health goals are a major part of the daily lives of those fighting chronic diseases. A proliferating population of patients with chronic diseases are participating in web-based patient communities, wherein they can exchange health information and pursue health goals with others virtually.

Objective

In this study, we aimed to understand the effect of participation in social media–enabled web-based patient communities on health goal attainment. In particular, we studied the antecedents of health goal attainment in terms of social support and self-reflection in web-based patient communities.

Methods

This data set consists of web-based health management activities of 392 patients across 13 health support groups, that is, groups with medical issues such as high blood pressure, diabetes, and breast cancer; the data of the activities were collected from a leading web-based patient community. Content analysis was used to code the social interactions among the patients on the web-based platform. Cox regression for survival analysis was used to model the hazard ratio of health goal attainment.

Results

Our analysis indicated that emotional support from web-based patient communities can increase patients’ probability of achieving their goals (hazard ratio 1.957, 95% CI 1.416-2.706; P<.001) while informational support does not appear to be effective (P=.06). In addition, health-related self-reflection increases the patients’ likelihood of goal attainment through web-based patient communities (hazard ratio 1.937, 95% CI 1.318-2.848; P<.001), but leisure-oriented self-reflection reduces this likelihood (hazard ratio 0.588, 95% CI 0.442-0.784; P<.001).

Conclusions

Social media–enabled web-based platforms assist health goal management via both social interaction and personal discipline. This study extends the understanding of web-based patient communities by investigating the effects of both social and cognitive factors on goal attainment. In particular, our study advocates that health goals relating to chronic conditions can be better managed when patients use the facilities of web-based health communities strategically.
Detection of Atrial Fibrillation Using a Wrist Photoplethysmogram: A Prospective Study on Patients Undergoing Catheter Ablation or Electrical Cardioversion (Preprint)
Authors: Liao Min-Tsun , Yu Chih-Chieh , Lin Lian-Yu , Pan Ke-Han , Tsai Tsung-Hsien , Wu Yu-Chun , Liu Yen-Bin
Published: July 2020

BACKGROUND

Atrial fibrillation (AF) is associated with an increased risk of stroke, heart failure, and all-cause mortality. The electrocardiogram (ECG)–based strategy of screening for AF has some limitations. Photoplethysmography (PPG) is used in AF detection algorithms and allows passive and continuous monitoring by modern wearable devices.

OBJECTIVE

The objective of this study was to investigate the following: (1) whether quantitatively analyzing wrist PPG waveforms can clearly distinguish AF from sinus rhythm and (2) to determine the appropriate data length of the PPG for feature extraction to optimize the PPG analytics program for AF detection.

METHODS

Continuous waveforms of ECG through an electrophysiology recording system and PPG signals through a wrist–worn smartwatch were simultaneously collected from patients undergoing catheter ablation or electrical cardioversion for AF. The PPG features (temporal, spectral, or morphological) were extracted from 10, 25, 40, or 80 heartbeats of split segments. Machine learning with a support vector machine (SVM) approach was used for detecting AF. The receiver operating characteristic (ROC) curves were determined to evaluate the diagnostic accuracy.

RESULTS

A total of 116 patients were evaluated. The mean age was 59.6±11.4 years and 32.8% were women. We collected and annotated more than 117 hours of PPG waveforms. A total of 6478 and 3957 segments of 25-beat pulse-to-pulse interval (PPI) were annotated as AF and sinus rhythm, respectively. A total of eight features were extracted to distinguish AF, including the PPI standard deviation (SD), PPI root-mean-squared standard deviation (RMSSD), Shannon Entropy with bin = 10, 100, 1000 (SE10, SE100, SE1000), moving average of 3 PPI SD, moving SD of 3 PPI RMSSD, and moving SD of maximum FFT frequency in 3 PPI. The accuracy of all the eight PPG features extracted from the 25 PPI achieved a test AUC (area under the receiver operating characteristic curve) which was significantly better than that from the 10 PPI (the AUC was 0.9676 versus 0.9453, respectively; P<2.2e-16).

CONCLUSIONS

This study demonstrated that quantitatively analyzing PPG waveforms can clearly discriminate the signals of AF from those of sinus rhythm. The appropriate data length of the PPG to optimize the PPG analytics program was 25 heartbeats.

CLINICALTRIAL

N/A
Healing the Wounds of War: Reducing Maternal Mortality in Darfur
Authors: Elzarov Zurab
Published: July 2020

Reducing maternal mortality rates in Darfur remains one of the major challenges to the healthcare system in Darfur owing to the on-going conflict, displacement of large number of population, poor transportation networks, destruction of primary healthcare facilities and the lack of solid mechanism to train village midwives. Under these circumstances, the United Nations—African Union Mission in Darfur (UNAMID) continues to invest in reducing the maternal and child mortality rates in Darfur by mobilizing the existing resources and advocating for availability of all services that are directed towards improving the maternal health in the region. The article highlights the positive changes and significant impact that these interventions have had on reducing the maternal mortality rates in Darfur and saving lives of children.
DESIGN, FORMULATION, AND CHARACTERIZATION OF APREMILAST-SACCHARIN COCRYSTALS LOADED WITH TOPICAL GEL
Authors: MANE TEJASWINI , MOHITE MUKESH
Published: July 2020

Objective: Most of the drugs are relevant to BSC class II and class IV having solubility problems. Cocrystallization of drug with conformer is an immense approach used to explore the physicochemical properties of drug. The objective of the present work was to design formulate and evaluate the drug cocrystals of poorly soluble drug apremilast (APR) with saccharin.

Methods: Cocrystals of APR were prepared using the solvent evaporation technique. The saturated solubility study and in vitro dissolution study of cocrystals were carried out. The prepared cocrystals were characterized by differential scanning calorimetry (DSC), X-ray diffraction (XRD), and Fourier-transform infrared (FTIR) spectroscopy. The topical gel of APR cocrystals was formulated optimized and evaluated using three-level factorial design.

Results: The cocrystals of APR were prepared in 1:1 molar ratio with saccharin. APR cocrystals showed the improvement in solubility and dissolution as compared to pure APR. The formation of cocrystals was confirmed from change in endothermic peak of DSC and from shifting of FTIR spectra of cocrystals. Crystallinity of cocrystal was confirmed from XRD pattern and noteworthy change in 2θ values of the intense peak. The topical gel of APR cocrystals was formulated and optimized using three-level factorial design using Carbapol-940 and hydroxypropyl methylcellulose (HPMC) as a gelling agent.

Conclusion: The cocrystals with altered physicochemical properties of APR were prepared with saccharin and formulated as a topical gel to overcome the problems related to oral administration.
CORRELATION BETWEEN POLYMORPHISMS OF FOXP3 T-REGULATORY PROMOTOR GENE WITH TGF-β IN PATIENTS WITH GRAVES’ DISEASE
Authors: ELVIRA DWITYA
Published: July 2020

Objective: The aim of this study is to prove that there are Forkhead Box P3 (FOXP3) T-regulator promoter polymorphisms in Graves’ disease and to analyze the association between FOXP3 T-regulator promoter polymorphisms with transforming growth factor (TGF)-β levels.

Methods: This study was an observational study with cross-sectional comparative study design. Consecutive sampling was conducted in patients with Graves’ disease who came to the outpatient clinic and treated in Dr. M. Djamil Hospital, Padang. Blood sampling was performed on 30 Graves’ subjects and 30 control subjects based on inclusion and exclusion criteria. DNA isolation, primary construction, and polymorphism identification by polymerase chain reaction method and blood sample examination by enzyme-linked immunosorbent assay techniques method for TGF-β examination were performed in this study.

Results: The results of this study obtained the most age of patients with Graves’ disease is 30–40 years with the female gender. Graves’ patient group was found to have 86.7% of single nucleotide polymorphisms (SNP) rs3761548 polymorphism, and 61.3% had SNP rs2232365 polymorphism followed by 26.7% polymorphism of SNP rs3761547 and rs3761549, and no SNP rs2232364 polymorphism was found. In Graves’ group, the mean value of TGF-β was 1030.01±277.64 ng/ml, significantly higher than the control group. Statistical analysis showed a significant relationship between polymorphism of the FOXP3 promoter gene and TGF-β level with p<0.05.

Conclusion: This study proves that there are polymorphisms of the FOXP3 promoter gene in Graves’ patients, especially SNP rs3761548 and rs2232365. The polymorphism of the FOXP3 promoter gene has a significant association with TGF-β levels.
ZIKA VIRUS: A BRIEF REVIEW
Authors: AL-TAMEEMI KANAAN , KABAKLI RAIAAN
Published: July 2020

This review highlights the Zika virus which is considered a global concern due to its rapid pandemic potential and effect on humans, and according to its pandemic status, the World Health Organization declared on February 2016 it as a “Public Health Emergency of International Concern.” Therefore, we define the epidemiology of Zika virus in addition to its pathogenesis, diagnostic techniques, and treatment.
Respon Penambahan Proporsi Bubur Rumput Laut Dengan Tepung Tapioka dan Konsentrasi Ekstrak Sawi Terhadap Mutu Bakso Ayam
Authors: Faricha Tri Mahdiyahtul , Winarsih Sri , Saati Elfi Anis
Published: July 2020

Meatballs are round or other food products derived from cattle meat mix (not less than 50% meat content) and starch or cereals with or without the addition of other food ingredients and permissible dietary ingredients. Meatballs in general have a rubbery texture approaching hard and have a less attractive color that needs to be done production innovation, one of them is by addition of green mustard extract with the composition of seaweed porridge and tapioca flour. This study aims to determine the effect of interaction between the proportion of seaweed porridge with tapioca starch and extract concentration, and each of these factors. The research was conducted by using Group Random Design (RAK) two factors. The factor I with 4 levels is the composition of seaweed porridge with tapioca flour, among others: 5%: 25%, 10%: 20%, 15%: 15%, 20%: 10%. Factor II with 3 levels is the addition of green mustard extract concentration (1: 1, 2: 1, 3: 1). Meatball testing is done on physicochemical properties (moisture content, ash, protein, fat, carbohydrate, antioxidant, total chlorophyll, texture, and color) and organoleptic (taste, aroma, joy, suppleness, and appearance. The results showed that interaction between substitution of seaweed with green bean extracts dye to moisture content, ash content, yellowishness (b+), total chlorophyll, antioxidant, taste score, elasticity score, appearance score, and no effect on protein content, brightness (L), yellowishness (a-), aroma score, favorite score. The best treatment of chicken meatball was obtained from R4S3 treatment with the addition of 20% seaweed porridge with 10% tapioca starch and 3: 1 green mustard concentration with 74.20% moisture content, 2.62% ash content, 2.53 fat content %, protein content 17.45%, carbohydrate 20.32%, chlorophyll 0.47 mg / L, and antioxidant 75.73%, texture of 4.96, brightness level (L) 62.47, yellowishness -) 7.07, greenishness (b +) 12.83. Furthermore, organoleptic test with organoleptic score 2.60 (enough), taste score 2.67 (good enough), aroma score 2.70 (quite like), the score of 2.90 (quite interesting), and score suppleness 2.83 (quite chewy). All of the parameters tested such as moisture content, ash content, protein content, and fat content have fulfilled SNI 01-3818 of 1995 chicken meatball.
Karakteristik Sifat Fisiko-Kimia Mi Basah Subtitusi Tepung Sorgum (Sorghum bicolor L. Moench) Diperkaya Serat Rumput Laut (Gracilaria sp.)
Authors: Waqiah Alifianti Nur , Damat Damat , Putri Desiana Nuriza
Published: July 2020

Noodles are consisting of main high protein flour. Data consumption of noodles in 2014 in Indonesia gain 2,2 million ton, this number was going high gradually in every next year. The substitute material which has similarities with what has been used in the last decade is sorghum starch. The aim of this study was to determine the effect of the composition of sorghum starch with seaweed pulp. The research method in is factorial Randomized Block Design (RBD). The first factor used was the difference in the ratio of wheat flour with sorghum starch which was added at 80:20; 60:40; 50:50 Factor II is the addition of seaweed which is 10%, 20%, and 30%. Quality starch noodles within analysis: water content, ash content, protein content, fat content, crude fiber content, and organoleptic (texture, taste, color, and aroma (smell)). The best results were obtained in the T1R1 treatment which got rank 1 with water content 33.38%, ash content 2.05%, protein content 8.31%, fiber content 12.92%, fat content 1.22%, organoleptic aroma 2.94 with aroma value "Quite tasty", organoleptic texture 3.76 with a value of "springy", color organoleptic 3.73 which is "attractive", organoleptic taste 3.76 that is "delicious".
Surgical treatment of military with multilevel lumbar vertebral spondylolysis
Authors: Khominets V. V. , Nadulich K. A. , Nagorny E. B. , Teremshonok A. V. , Kudyashev A. L. , Averkiev D. V. , Strelba A. A.
Published: July 2020

Purpose. To demonstrate the effectiveness of an isolated fixation technique of multilevel spondylosis disorders in young patients.

Materials and methods. Two military men were operated for multilevel spondylosis of lumbar vertebra (LII, LIV and LIV, LV).

Results and discussion. Patients underwent bone autoplasty and osteosynthesis of vertebral arches using hybrid lamina transpedicular system in a screw-rod-hook form. Good anatomic and functional results were got.

Conclusion. Avoidance of fixation of intact functional spinal units allows to achieve good treatment results and classify this operation as organ sparing surgery.
Что фактически фиксируется в качестве исторического поселения
Authors: Shevchenko Eleonora
Published: July 2020

Выявление на территории современного населённого пункта некой чётко локализуемой объёмно-пространствен­ной и планировочной целостности, характеризуемой как историческое поселений, представляет и сегодня серьёзную проблему. Суть проблемы заключается в размытости понятия «историческое поселение», установленного в действующем Федеральном законе «Об объектах культурного наследия (памятниках истории и культуры) народов Российской Феде­рации» от 25.06.2002 № 73-ФЗ. Нечёткость и неконкретность формулировки «предмета охраны» исторического поселения, также усложняет, а в ряде случаев делает невозможной чёт­кую локализацию такого уникального градостроительного исторического объекта, как «Историческое поселение».

В статье рассматривается проблема локализации объ­ёмно-пространственной и планировочной целостности исторического поселения. Представлены результаты анализа законодательно введённого определения «Историческое по­селение» и его некорректность. Доказывается, что основопо­лагающим фактом, подтверждающим наличие исторического поселения на территории современного населённого пункта, следует признать сохранившуюся историческую среду даже в случае отсутствия объектов культурного наследия. Осно­ванием такого утверждения является признание ценнейшим достоянием материализованной в предшествующие периоды времени нематериальной действительности. Именно истори­ческая среда поселения является ярчайшим материальным свидетельством этой нематериальной действительности или творческой деятельности ушедших поколений граждан кон­кретного поселения. Это именно то, что необходимо выявить для того, чтобы установить правила эксплуатации в целях сохранения для будущих поколений.
Знаки войны и беды в наследии и современной церковной архитектуре Беларуси
Authors: Slyunkova Inessa
Published: July 2020

Статья посвящена 75-летию победы народа в Великой Отечественной войне. Масштабы разрушений Беларуси в годы войны не поддаются методам исчисления, они невосполнимы, и для республики, как показывает время, традиционный опыт реставрации не является универсальным решением проблемы возвращения ценностей исторического прошлого. В статье внимание сосредоточено на исследовании особого пути Беларуси в деле возрождения храмов.Судьба наследия церковной архитектуры республики рассматривается, начиная с военных утрат и последующего забвения сакральных объектов, до времени возрождения храмов. Поднимается тема обращения к понятию «знак беды», вопросы состояния церковной архитектуры Беларуси на рубеже XX–XXI веков. Отмечены тенденции современного искусства к превращению трагических смыслов историив синонимы преодоления и национального возрождения. Представлены главные приметы нашего времени, связанные с воссозданием и реставрацией ценных объектов насле-дия. Воссоздание Успенского собора в Витебске послужило цели возрождения архитектурной доминанты древнего города. Собор был построен монахами ордена базилианов при участии итальянских мастеров (1743–1777) и уничтожен в годы атеизма (1936). Передача верующим и реставрация Николаевского гарнизонного собора в Брестской крепости позволила вернуть в культуру выдающийся памятник архитектуры византийского стиля эпохи историзма. Храм был построен по проекту академика Д.И. Гримма (1874–1877), и летом 1941 года в огне обороны Брестской крепости от фашистов он был разрушен. Показано, как решалась проблема компенсации утраченных в войну церковных зданий путём устройства временных церк-вей на территории Беларуси в начале XXI века. Поднимаются вопросы поисков современной типологии архитектуры православного храма. Особое внимание отво-дится строящейся в Минске церкви во имя Всех Святых по всему миру просиявших. Затрагиваются вопросы семантики архитектуры военного мемориала в стенах храма-памятника.
Деревянное храмостроительство нижнего Поонежья XIX - начала ХХ века
Authors: Bode Andrei , Khodakovsky Evgeny
Published: July 2020

еревянное церковное зодчество XIX - начала ХХ века представляет собой малоизученную часть российского архи­тектурного наследия, в советское время совершенно забытую. Храмовое строительство исследуется на примере объектов в районе нижнего течения реки Онеги. Исследование основа­но на архивных источниках, выявленных в Государственном архиве Архангельской области, и материалах натурных обсле­дований объектов. В научный оборот вводится значительный объём исторических документов и проектов, раскрывающий специфику процесса подготовки и строительства деревянных храмов в провинции. Анализируются стилистические изменения, происходившие в течение рассматриваемого периода: от эклектики до преобладания русских мотивов. Внимание заостряется на использовании образцовых проектов и их интерпретациях. Образцовые проекты упрощались, что было характерно для всех отдалённых провинций страны. Строи­тельство, производившееся крестьянскими артелями, ещё более отдаляло результат от проекта и вносило в постройку дух народного зодчества.

В работе рассмотрены объекты, характеризующие ос­новные тенденции и особенности деревянного церковного строительства исследуемого периода. Ильинская церковь в селе Большой Бор, построенная почти точно по образцовому проекту, была достроена для удобства и улучшения общего вида. Троицкая церковь в деревне Мондино достаточно смело интерпретирует решения, взятые из образцовых проектов, и вместе с тем наследует формы предшествующих утраченных церквей. В архитектуре Ильинской церкви в деревне Камен­ное явно присутствуют влияния русского стиля. Церковь в деревне Канзапельда являет пример перестройки часовни в церковь, что нередко делалось в целях экономии строи­тельных ресурсов.

В деревянном церковном строительстве XIX века, несмотря на стилистические изменения, отчётливо присутствует пре­емственность с развитием архитектуры предыдущих веков. Соединение нового и традиционного, стилевого и народного составляет специфику деревянной церковной архитектуры на заключительном этапе её развития[1].

 

[1]     Статья подготовлена при финансовой поддержке РФФИ в рамках на­учного проекта № 20-012-00356 «Архитектура деревянных храмов Онежского Поморья XVII-XIX веков. Типология, эволюция, региональные традиции».
MODELING TO IMPROVE THE PERFORMANCE OF REVERSE POWER RELAY IN GENERATOR
Authors: Zakri Azriyenni Azhari , Rozi Fahrul
Published: July 2020

The generator is the primary component in electricity generation and requires a protection system from internal and external interference that occurs. This study considers how to improve the performance of relays in power plants. A model of a generator that is executed in a fault condition to reset the protective equipment, namely Reverse Power Relay (RPR). The study is intended to model the state of internal and external fault on the generator by applying a working principle of RPR. The model is designed to anticipate the actual fault in the generator. The simulation results obtained output such as; active power, current and time delay relay. The RPR reset of the generator system is applied to the generator in Riau Power. The RPR is installed on the generator is -612 kW, equivalent to 30%, the relay delay time is 0.2 seconds. Based on standardization, the return of power reaches a maximum of -12.66 MW, which is captured 50% with a maximum replacement of 30 seconds. Results of the RPR simulation have been validated with the IEEE standard at a time delay that corresponds to the percentage of reverse power settings installed at 6% and a time delay of 0.6%. Finally, to maximize the protection system on the generator, adjust 50% to 95% of the installed settings. It can be said that the system is able to increase generator protection and minimize the impact of internal or external fault.
PROPOSE SAFETY ENGINEERING CONCEPT SPEED LIMITER AND FATIGUE CONTROL USING SLIFA FOR TRUCK AND BUS
Authors: Pranoto Hadi , Adriansyah Andi , Feriyanto Dafit , Wahab Abdi , Zakaria Supaat
Published: July 2020

In 2015, there were 55 deaths from 6,231 accident cases that occurred in Jakarta. A severe problem in Indonesia is the absence of a unique safety device in both commercial transport or personal vehicles and the very high complexity problem of human highways. Consequently, there are many traffic accidents caused by the negligence of the driver, such as driving a vehicle in a drunken, tired, drowsy, or over-limit speed. Therefore, it needs to be innovative using devices to increase speed but able to detect the level of tired or sleepy drivers. This paper tries to propose a concept of improving safety engineering by developing devices that can control the speed and level of safety of trucks and buses, named SLIFA. The proposed device captures the driver's condition by looking at the eyes, size of mouth evaporating, and heart rate conditions.  Theses condition will be measured with a particular scale to determine the fatigue level of the driver. Some performance tests have been carried out on truck and bus with 122 Nm and 112 Nm torque wheels and 339 HP and 329 HP power values, respectively, and the minimum speed is 62 km/h. At a top speed of 70 km / h, the torque and power of the truck are 135Nm and 370HP, with average fuel consumption of 3.43 liters/km before SLIFA installation and average fuel consumption of 4.2 liters/km after SLIFA installation. SLIFA can be said to have functional eligibility and can cut fuel consumption by 81 percent.
Vratkovići i drugi Morlaci u trogirskome distriktu u 16. stoljeću
Authors: Juran Kristijan
Published: July 2020

Recentna je historiografija iznjedrila
nekolicinu zapaženih radova o mletačko-osmanskim odnosima na trogirskome
pograničju u 16. stoljeću i ulozi koju su u njima imali novodoseljeni osmanski
Morlaci. Iako je i ovaj prilog usmjeren k istome cilju, temeljna mu je nakana
rasvijetliti još uvijek zamućenu i nedovoljno razrađenu problematiku
prisutnosti morlačkih plemena (katuna) u pojedinim selima trogirskoga distrikta
u razdoblju od 1530. do 1600. godine. Ovdje se o njima donose nove vijesti,
uglavnom iz arhivskih spisa trogirske provenijencije.
O pitanjima alkoholizma i protualkoholnoga djelovanja početkom 20. stoljeća u Trojednoj Kraljevini
Authors: Salopek Bogavčić Iva
Published: July 2020

Članak na temelju arhivskih fondova čuvanih u državnim arhivima, statističkih pokazatelja, relevantne literature, novina te članaka iz časopisa “Novi naraštajˮ i “Novi životˮ sagledava problematiku alkoholizma i početke borbe protiv alkoholizma do 1914. godine na prostoru Kraljevine Hrvatske i Slavonije te Kraljevine Dalmacije. Pitanje ozbiljnosti alkoholizma na našim prostorima aktualizirali su Fran Gudrum Oriovčanin, Nikola Đurić i Andrija Štampar kritički sagledavši problem u svojim pisanim osvrtima te pokretanjem edicija i dvaju časopisa na tu temu. U članku se propituju uzroci pojave takvih društava, društveni stereotipi o alkoholu kao i prva statistička vrednovanja utjecaja alkoholizma na društvo. Formiranjem Društva apstinenata u Kraljevini Hrvatskoj i Slavoniji godine 1912. započeo je sustavniji formalni oblik borbe protiv alkoholizma, koji je s vremenom zaživio osnivanjem podružnica po manjim mjestima diljem Kraljevina. Vrhunac djelovanja protualkoholnoga pokreta uviđa se u organizaciji izložbe godine 1914. u Umjetničkome paviljonu kao i u sudjelovanju hrvatskoga predstavnika na IV. austrijskome antialkoholnom kongresu u Brnu
Density functional theory calculation of propane cracking mechanism over chromium (III) oxide by cluster approach
Authors: Oyegoke Toyese , Dabai Nyako , Uzairu Adamu , Jibril El-Yakubu
Published: July 2020

The catalyst coking and production of undesired products during the transformation of propane into propylene have been the critical challenges in the on purpose approach of propylene production. The mechanism contributing to this challenge was theoretically investigated through the analysis of cracking reaction routes. The study carried out employed the use of a density functional theory and cluster approach in order to understand the reactions that promote coking of the catalyst and in the search for the kinetic and thermodynamic data of the reaction mechanism involved in the process over Cr2O3. The ratedetermining step and feasible route that easily promote the production of small hydrocarbons like ethylene, methane, and many others were identified. The study suggests Cr-site substitution or co-feeding of oxygen can aid in preventing deep dehydrogenation in the conversion of propane to propylene. This information will help in improving the Cr2O3 catalyst performance and further increase the production yield.
Analytical and numerical models compared with measurements for analysis of electromagnetic radiation through apertures of a metallic enclosure
Authors: Azizi Hakim , Chebout Mohammed , Moulai Hocine , Bréard Arnaud , Vollaire Christian
Published: July 2020

Generally, most of the electronic equipments need a metallic enclosure in
order to mechanically protect and electrically shield the interior printed
circuit boards (PCBs) and subsystems. But in practical situations, the
apertures or slots of various forms are essential parts of the shielding
enclosure for thermal dissipation, CD-ROMs, connectors, I/O cabling and so
on. The performance of shielding enclosures for high-speed digital systems
is compromised by these inevitable discontinuities on enclosure. To minimize
the electromagnetic interferences and susceptibility risks by these
discontinuities, the shielding enclosures with apertures should be designed
based on thorough analysis about the electromagnetic coupling mechanism
through apertures. In this paper, the effect of apertures and oblique
incident plane wave on shielding effectiveness of the enclosure is studied
with the Circuital Approach, and the Finite-Difference Time-Domain (FDTD)
method, the simulated SE data are verified by experimental technique. Good
agreements are found between these approaches.
Analysis of signal quality in FSO systems with PolSK modulation
Authors: Todorovic Jelena , Jaksic Branimir , Spalevic Petar , Bandjur Djoko , Bandjur Milos
Published: July 2020

In this paper, the quality of the Polarization Shift Keying (PolSK) modulated
signal in a Free Space Optical (FSO) system is analyzed. The atmospheric
channel is statistically modeled with four different distributions, namely,
the Gamma-Gamma distribution, Negative Exponential distribution,
Kdistribution, and I-K distribution. For all four channel models, the
Average Bit Error Rate (ABER) at the receiving side of the system is
determined in an analytically closed form. The results are graphically
presented and discussed in order to determine the impact of certain
parameters on the ABER, i.e., the quality of the received signal in the
PolSK modulated FSO system. These parameters are the Signal-to-Noise Ratio
(SNR), the FSO link distance, the wavelength at which the signal is
transmitted, and the atmospheric turbulence strength.
Optimization of synchronous reluctance motor based on radial basis network
Authors: Nik Amirhossein , Faiz Jawad
Published: July 2020

This paper presents surrogate-model based optimization for synchronous
reluctance motor (SynRm) with transversally laminated rotor. A radial basis
function (RBF) model with 12 input variables and three outputs is first
trained. A dataset is obtained using finite element method to estimate
parameters of RBF model. By building RBF model, the RBF network can predicts
the outputs of the SynRm with good accuracy Using non-dominated sorting
genetic algorithm (NSGA II), pareto front is obtained. The SynRm is designed
to maximize the maximum developed torque and power factor of the motor with
constrained torque ripple.
Analytical solution for determination of induction machine acceleration based on Kloss equation
Authors: Koljcevic Nikola , Fustic Zeljko , Calasan Martin
Published: July 2020

In this paper, the analytical solution for the determination of induction
machine acceleration, i.e. acceleration-time characteristic, during no-load
direct start-up is proposed. The proposed dependence is derived from the
Kloss equation for torque-speed relation for the induction machine. Also,
the analytical solution for the maximal value of the acceleration is derived
in this paper. The results obtained using developed expressions are compared
with corresponding results obtained using the developed Matlab/Simulink
model for analyses of the induction machine starting the process. Therefore,
very high degree of accuracy is obtained.
Dosimetric verification of clinical radiotherapy treatment planning system
Authors: Kolarevic Goran , Jaros Drazan , Marosevic Goran , Ignjatic Dejan , Mirjanic Dragoljub
Published: July 2020

Background/Aim. In the past two decades, we have witnessed the emergence of new radiation therapy techniques, radiotherapy treatment planning system (TPS) with calculating algorithms for the dosage calculation in a patient, units for multislice computed tomography (CT) and image-guided treatment delivery. The aim of the study was investigating the significant difference in dosimetric calculation of radiotherapy TPS in relation to the values obtained by measuring on the linear accelerator (LINAC), and the accuracy of dosimetric calculation between calculating algorithms Analytical Anisotropic Algorithm (AAA) and Acuros XB in various tissues and photon beam energies. Methods. For End-to-End test we used the hetero-geneous phantom CIRS Thorax002LFC, which anatomically represents human torso with a set of inserts known as relative electron densities (RED) for obtaining a CT calibration curve, comparable to the ?reference? CIRS 062M phantom. For the AAA and Acuros XB algorithms and for 6 MV and 16 MV photon beams in the TPS Varian Eclipse 13.6, four 3D conformal (3DCRT), and one intensity modulated (IMRT) and volumetric modulated arc (VMAT) radiotherapy plans were made. Measurements of the absolute dose in Thorax phantom, by PTW-Semiflex ionization chamber, were carried out on three Varian-DHX LINACs. Results. The difference between ?reference? and measured CT conversion curves in the bone area was 3%. For 476 phantom measurements, the difference between measured and TPS calculated dose of 3?6%, was found in 30 (6.3%) cases. According to regression analysis, the standardized Beta coefficient for relative errors, 6 MV vs. 16 MV, was 0.337 (33.7%, p < 0.001). Mean relative errors for AAA and Acuros XB, using Mann-Whitney test, for bones were 1.56% and 2.64%, respectively (p = 0.004). Conclusion. End-to-End test on Thorax002LFC phantom proved the accuracy of TPS dose calculation in relation to the one delivered to a patient by LINAC. There was a significant difference for photon energies relative errors (higher values are obtained for 16 MV vs. 6 MV). A statistically significant minor relative error in AAA vs. Acuros XB was found for the bone.
Selection of the optimal medical waste incineration facility location: A challenge of medical waste risk management
Authors: Stanojevic Kristina , Radovanovic Goran , Makajic-Nikolic Dragana , Savic Gordana , Simeunovic Barbara , Petrovic Natasa
Published: July 2020

Background/Aim. Among the other challenges of the 21st century, medical waste (MW) has become an arising problem for both the environment and people because of its increasing amount, variety, and complexity. That is way MW management has become one of the very important ecological imperatives. Serbia with no potential for appropriate disposal of all MW is forced to export MW to countries with MW incineration facilities. Incineration lowers the possible risks of inappropriate disposal and the emission of environmental pollutants, but leads to the need for a ?clever? choice of the incinerator facility location which has to meet diverse environmental, economic and technical criteria Methods. The criteria for the choice of optimal locations for a MW incinerator facility were as follows: the amount of MW that needs to be transported, the transport time from other locations, the current pollution of the location, the unemployment rate and the location safety in terms of natural disasters and accidents. By using the obtained results for seven efficient locations gained by Data Envelopment Analysis (DEA), we used a goal programming for the analysis of the most suitable location for a MW incineration facility. Results. In the proposed methodology on the chosen scenario and analysing the criteria relevant for selecting the most suitable location, using the DEA method, seven efficient locations for MW incineration facility were obtained. The optimal location was location 13. Conclusion. Based on the obtained results, we demonstrated that by the use of goal programming it is possible to develop a methodology for selection of optimal MW incineration facility location as one of the necessary activities of MW risk management.
Auditors' and Specialists' Views About the Use of Specialists During an Audit
Authors: Boritz J. Efrim , Kochetova Natalia V. , Robinson Linda A. , Wong Christopher
Published: July 2020

Auditors often rely on the assistance of specialists from such fields as tax, information technology, valuation, and forensic accounting. Integration of the work of specialists with the work of audit team members is a challenge for both groups. This interview-based study of 34 practitioners from six accounting firms, including 12 auditors (partners and managers) and 22 specialists (tax, IT, valuation, forensic) examines auditors' and specialists' views about the current state of specialist use on audits. The regulatory environment creates pressure for financial statement auditors to use specialists on audits; however, financial statement auditors often seek to limit specialist involvement. Both auditors and specialists are dissatisfied with the current situation, but for different reasons. Auditors are concerned about budget overruns, delays, and harm to client relationships by (overly) meticulous specialists. Specialists are concerned about auditors limiting the scope of specialist involvement, and its effect on audit quality.

JEL Classifications: M4; M40; M42.
Clinical Parameters, Fuel Oxidation, and Glucose Kinetics in Patients With Type 2 Diabetes Treated With Dapagliflozin Plus Saxagliptin
Authors: Qin Yuejuan , Adams John , Solis-Herrera Carolina , Triplitt Curtis , DeFronzo Ralph , Cersosimo Eugenio
Published: July 2020

OBJECTIVE

To examine the mechanisms responsible for improved glycemia with combined sodium–glucose cotransporter 2 inhibitor (SGLT2i) plus dipeptidyl peptidase 4 inhibitor therapy in type 2 diabetes.

RESEARCH DESIGN AND METHODS

Fifty-six patients (HbA1c 8.9 ± 0.2% [74 ± 2 mmol/mol]) were randomized to dapagliflozin (DAPA) 10 mg, DAPA/saxagliptin (SAXA) 10/5 mg, or placebo (PCB) for 16 weeks. Basal endogenous glucose production (EGP) (3-3H-glucose), urinary glucose excretion, glucose/lipid oxidation, HbA1c, and substrate/hormone levels were determined before treatment (Pre-Tx) and after treatment (Post-Tx).

RESULTS

At week 16, HbA1c decrease was greater (P < 0.05) in DAPA/SAXA (−2.0 ± 0.3%) vs. DAPA (−1.4 ± 0.2%) and greater than PCB (0.2 ± 0.2%). Day 1 of drug administration, EGP (∼2.40 mg/kg/min) decreased by −0.44 ± 0.09 mg/kg/min in PCB (P < 0.05) but only by −0.21 ± 0.02 mg/kg/min in DAPA and DAPA/SAXA (P < 0.05 vs. PCB). At week 16, EGP increased to 2.67 ± 0.09 mg/kg/min (DAPA) and 2.61 ± 0.08 mg/kg/min (DAPA/SAXA), despite reductions in fasting plasma glucose by 47 and 77 mg/dL, respectively, and no changes in PCB. Baseline plasma free fatty acids rose by 40 µmol/L with DAPA but declined by −110 with PCB and −90 µmol/L with DAPA/SAXA (P < 0.05, Pre-Tx vs. Post-Tx). In DAPA, carbohydrate oxidation rates decreased from 1.1 ± 0.1 to 0.7 ± 0.1 mg/kg/min, whereas lipid oxidation rates increased from 0.6 ± 0.1 to 0.8 ± 0.1 mg/kg/min (P < 0.01). In DAPA/SAXA, the shift in carbohydrate (1.1 ± 0.1 to 0.9 ± 0.1 mg/kg/min) and lipid (0.6 ± 0.1 to 0.7 ± 0.1 mg/kg/min) oxidation was attenuated (P < 0.05).

CONCLUSIONS

The addition of SAXA to DAPA resulted in superior glycemic control compared with DAPA monotherapy partly because of increased glucose utilization and oxidation. Although the decrease in insulin/glucagon ratio was prevented by SAXA, EGP paradoxical elevation persisted, indicating that other factors mediate EGP changes in response to SGLT2i-induced glucosuria.
Randomized Double-Blind Clinical Trial Comparing Ultra Rapid Lispro with Lispro in a Basal-Bolus Regimen in Patients with Type 2 Diabetes: PRONTO-T2D
Authors: Blevins Thomas , Zhang Qianyi , Frias Juan P , Jinnouchi Hideaki , Chang Annette M
Published: July 2020

OBJECTIVE

To evaluate the efficacy and safety of ultra
rapid lispro (URLi) versus lispro in patients with type 2 diabetes on a
basal-bolus insulin regimen.

RESEARCH
DESIGN AND METHODS

This was a Phase 3, treat-to-target, double-blind
26-week study. After
an 8-week lead-in to optimize basal insulin glargine or degludec in combination
with prandial lispro treatment, patients were
randomized to blinded URLi (n=336) or lispro (n=337) injected 0 to 2 minutes
prior to meals. Patients could continue metformin and/or sodium glucose
co-transporter-2 inhibitor. The primary end point was change from baseline
HbA1c to 26 weeks (noninferiority margin 0.4%), with multiplicity adjusted
objectives for postprandial glucose (PPG) excursions during a standardized meal
test.

RESULTS

HbA1c improved for both URLi and lispro and
noninferiority was confirmed: estimated treatment difference (ETD) +0.06% (95%
CI -0.05; 0.16). Mean change in HbA1C was -0.38% for URLi and -0.43% for lispro,
with an end of treatment HbA1c of 6.92% and 6.86% respectively. URLi was
superior to lispro in controlling 1- and 2-h PPG excursions: 1-hour ETD, -0.66
mmol/L (95% CI -1.01, -0.30); 2-hour ETD, -0.96 mmol/L (-1.41, -0.52). Significantly
lower PPG excursions were evident from 0.5 to 4 hours postmeal with URLi
treatment. There were no significant treatment differences in rates of severe
or documented hypoglycemia (<3 mmol/L). Incidence of overall
treatment-emergent adverse events was similar between treatments.

CONCLUSIONS

URLi compared with lispro in a basal-bolus
regimen was confirmed to be noninferior for HbA1c and superior to lispro for PPG
control in patients with type 2 diabetes.
Analisis Efisiensi dan Skala Ekonomis Pada Industri Kerajinan Anyaman Bambu Kecamatan Susut Kabupaten Bangli
Authors: Wilanda Taranitha Putri , Rustariyuni Surya Dewi
Published: July 2020

This study aims to analyze; 1) simultaneously, and analyze the partial effect of the use of production factors labor, work experience and capital for various products of the bamboo weaved craft industry, 2) to investigate the economies of scale and 3) analyze the efficiency of production factors in the bamboo weaved handicraft industry in Kecamatan Susut, Kabupaten Bangli. The type of data in this study is quantitative and qualitative data with primary and secondary data sources. Respondents in this study amounted to 93 peoples, a sample of 1277 craftsmen and calculated using the Slovin's formula. The determination of the sample size in each village was determined by the disproportional stratified random sampling method. Data analysis techniques used in this research is the analysis techniques of Cobb-Douglass, economies of scale, and economic efficiency. The results showed that the variable labor (X1), work experience (X2), and capital (X3) simultaneously and partially had a positive and significant impact on the amount of production (Y) to the bamboo weaved craft industry in Susut District, Bangli Regency. Economies of scale test in a state of increasing return to scale, but partially still in a decreasing return to scale condition. The efficiency of the use of production factors has not been efficient.
Analisis Struktur Perekonomian Berdasarkan Pendekatan Input- Output di Provinsi Jawa Timur
Authors: Lestari Endah Kurnia , Jannah Olvi Mifta Alfiatul
Published: July 2020

This study aims to (1) discover the shift of economic structure of East Java Province period 2010 and 2015; (2) to identify the various leading sectors in economic development in East Java Province Period 2010 and 2015. The analysis method used in this research is quantitative descriptive by using the Input-Output approach. The linkages between sectors of the economy, leading sectors, and economic sector multipliers have widely used to analyze this approach. Furthermore, structural shifts are analyzed using a multiplier product matrix (MPM) that can describe the landscape of an economy. The results showed that based on the analysis of MPM has not occurred a shift in economic structure significantly. However, there has been a change in the tertiary sector. Although until now, the economy of East Java Province is still dominated by the secondary industry. The leading industry of East Java Province is owned by the manufacturing industry, although there are other potential sectors as the leading sector.
Hukum OKUN: Pertumbuhan Ekonomi dan Tingkat Pengangguran di Indonesia
Authors: Astari Mayra , Hamzah Lies Maria , Ratih Arivina
Published: July 2020

This study examined the validity of Okun's Law on the Indonesian economy by using the difference version of Okun's Law to obtain the Okun coefficient. This study uses the analysis of the Autoregressive Distributed Lag Model (ARDL). The estimation results concluded that Okun's Law proved to have a negative and significant effect on the Indonesian economy because the variable economic growth was shown to influence the unemployment variable statistically.
Faktor-faktor Pertimbangan Mahasiswa UNILA dalam Pemilihan Rumah Indekos dikelurahan Kampung Baru dan Gedung Meneng Bandar Lampung
Authors: Wijoyo Setyo , Maimunah Emi
Published: July 2020

This study aims to determine what factors are considered by Lampung University students by choosing boarding houses. The data used are primary data obtained from the questionnaires' results, which are data on students' perceptions by choosing boarding homes. The sampling technique used was the Non-Probability Sampling method with the type of Convenience Sampling. This research uses a descriptive quantitative method. This study concludes that factors are considered students to a selection of boarding houses in Kampung Baru and GedungMeneng Bandar Lampung: variable with average, reference, rental price, location excellence, and facilities completeness.
Faktor-faktor Yang Mempengaruhi AHH Provinsi Bali
Authors: Darmayanti Luh Dita , Rustariyuni Surya Dewi
Published: July 2020

The degree of public health can be measured by looking at the amount of Life Expectancy (AHH). AHH is the result of calculating projections often used as one of the People's Welfare Indicators (IKR). Assuming a declining trend in infant mortality rates (IMR) and changes in the population's age composition, the objectives in this study are: 1) to analyze the effect of income per capita, government spending in education, and health simultaneously affect life expectancy in Bali Province / City in the 2011-2017 period and 2) to analyze the effect of per capita income, government spending the education and health sector influences the life expectancy in the Regency / City of Bali Province in the 2011-2017 period. The data used in this study is secondary data in 2011-2017. This study uses Multiple Linear Regression analysis techniques used to process classical assumption test data using Eviews 9. The results of this study stated that the variable income per capita (X1), government expenditure in education (X2), and government expenditure in health (X3) simultaneously affected the life expectancy (Y) in districts/cities in Bali Province. Partially per capita income has a positive and significant impact on life expectancy. Government expenditure in education and government expenditure in health does not affect life expectancy in Bali Province districts/cities.
Pola Pertumbuhan Ekonomi Daerah Otonomi Baru (DOB) Berdasarkan Tipologi Klassen di Provinsi Lampung
Authors: Ciptawaty Ukhti
Published: July 2020

The abstract is written in English. The abstract contains the research objectives. The importance of regional expansion is used as one of the reasons to encourage the acceleration of economic growth in a region. In the macro analysis, the level of economic growth achieved by a country/region is measured by the development of real national income achieved by an area. Therefore, the author wants to see how the structure of economic growth in the new autonomous region after the enactment of regional expansion. So the question raised through this research is how the pattern and structure of economic growth in each DOB so that it becomes the input for the DOB concerned to increase economic growth in the area. Therefore, the purpose of this study has the main objective of finding patterns and structures of economic growth in each DOB.