bluuebunny/crossref_metadata_2025 huggingface dataset:
Estudio meteorológico de la supercélula tornádica del 26 de agosto de 2019 en Campillos (Málaga)
Authors: Jiménez Alonso Carlos , Jiménez Cavero Carlos Manuel , Perea Hitos Carlos , Riesco Martín Jesús
Published: November 2020

Estudio meteorológico de un episodio tormentoso con características supercelulares y tornados asociados, ocurrido el 26 de agosto de 2019 en las cercanías de Campillos (Málaga).
Exposure to Traffic-Generated Pollutants Exacerbates the Expression of Factors Associated with the Pathophysiology of Alzheimer’s Disease in Aged C57BL/6 Wild-Type Mice
Authors: Armstrong Tyler D. , Suwannasual Usa , Kennedy Conner L. , Thasma Akshaykumar , Schneider Leah J. , Phillippi Danielle , Lund Amie K.
Published: November 2020

Background: Multiple studies report a strong correlation between traffic-generated air pollution-exposure and detrimental outcomes in the central nervous system (CNS), including Alzheimer’s disease (AD). Incidence of AD is rapidly increasing and, worldwide, many live in regions where pollutants exceed regulatory standards. Thus, it is imperative to identify environmental pollutants that contribute to AD, and the mechanisms involved. Objective: We investigated the effects of mixed gasoline and diesel engine emissions (MVE) on the expression of factors involved in progression of AD in the hippocampus and cerebrum in a young versus aged mouse model. Methods: Young (2 months old) and aged (18 months old) male C57BL/6 mice were exposed to either MVE (300μg/m3 PM) or filtered air (FA) for 6 h/d, 7 d/wk, for 50 d. Immunofluorescence and RT-qPCR were used to quantify oxidative stress (8-OHdG) and expression of amyloid-β protein precursor (AβPP), β secretase (BACE1), amyloid-β (Aβ), aryl hydrocarbon receptor (AhR), cytochrome P450 (CYP) 1B1, angiotensin-converting enzyme (ACE1), and angiotensin II type 1 (AT1) receptor in the cerebrum and hippocampus, in addition to cerebral microvascular tight junction (TJ) protein expression. Results: We observed age-related increases in oxidative stress, AhR, CYP1B1, Aβ, BACE1, and AT1 receptor in the CA1 region of the hippocampus, and elevation of cerebral AβPP, AhR, and CYP1B1 mRNA, associated with decreased cerebral microvascular TJ protein claudin-5. MVE-exposure resulted in further promotion of oxidative stress, and significant increases in AhR, CYP1B1, BACE1, ACE1, and Aβ, compared to the young and aged FA-exposed mice. Conclusion: Such findings suggest that MVE-exposure exacerbates the expression of factors in the CNS associated with AD pathogenesis in aged populations.
COMMUNITY SERVICE ACTIVITY TO HOUSEWIFE GROUP IN KAMPUNG LADANG BAMBU, MEDAN TUNTUNGAN
Authors: Ayu Putri Chandra
Published: November 2020

Purple sweet potato is one of the agricultural products that has several advantages such as attractive color, high content of antioxidant, fiber and carbohydrate compounds and has a low glycemic index value. However, similar to the other agricultural products, the availability of purple sweet potatoes is seasonal, perishable, moldy and rotten. Proper processing with equipment or simple expertise can increase the economic value of purple sweet potato, so that it can be done by any group of people from either upper, middle or bottom. The purpose of this community service activities was to provide the technical guidance on processing the purple sweet potato into food products, namely noodles and sponge to open new business opportunities for group of housewives in the area of ​​community service partners namely Kampung Ladang Bambu, Medan Tuntungan. The expected outcome of this community service activity is the formation of a new business by a group of housewives to be able to increase the community income in Ladang Bambu Village, Medan Tuntungan.

Keyword:, noodle, purple sweet potato, sponge
Usefulness of Delivery Methods for Communicating Climate Change Issues: Perspectives of Extension Professional and Research Faculty in the Northeast
Authors: Thorn Kaila , Radhakrishna Rama , Tobin Dan , Chatrchyan Allison , Chan Joana , Allred Shorna
Published: November 2020

Findings from this study provide insight into the delivery methods that land-grant university research and Extension personnel in the Northeast perceive as most effective to disseminate information as well
as to change practices or behaviors related to climate change. The respondents of this study represented research faculty, Extension specialists, and Extension educators from the 16 land-grant universities in the Northeastern U.S.
Clovercrest Farm: A Family Dairy in Charleston, Maine
Authors: Schattman Rachel
Published: November 2020

Clovercrest Farm is a small-scale dairy farm owned by Steve Morrison and Sonja Heyck-Merlin located in Charleston, Maine, 25 miles outside of Bangor.
Farming the floodplain: New England river governance in a changing climate (Hand-outs)
Authors: Schattman Rachel
Published: November 2020

You are worried about flood impacts from the river that borders your property. While you have
considered building a levee and placing stones along the bank to protect you land and house
from erosion, you do not have the equipment or expertise to do so. Additionally, you have seen
water velocity in the river increase because the farmer upstream has channeled the river. You
blame the farmer for putting your land and house at greater flood risk. You think that upstream
land should be allowed to flood to slow water velocity and absorb floodwaters; this would
protect you and your neighbors from future floods.
How Do Farmers Think about Climate Risk? A Study of On-Farm Decision Making in an Era of Climate Change
Authors: Schattman Rachel
Published: November 2020

climate forecasts suggest farmers in the northeast will be faced with both challenges and opportunities as the climate changes. currently farmers and other land stewards manage the risks created by changing weather patterns in many different ways.
Cover Cropping to Improve Climate Resilience
Authors: Bjorkman Thomas , Cavigelli Michel , Dostie Dan , Faulkner Joshua , Knight Lynn , Mirsky Steven , Smith Brandon
Published: November 2020

Heavy rains are becoming more frequent across the Northeastern United States and increasing soil erosion and nutrient runoff problems. Wetter weather in the spring and fall is reducing the number of days that fields can be worked.
Assessment of Climate Change Vulnerability and Adaptation and Mitigation Strategies in the Southwest and California
Authors: Elias Emile , Steele Caiti , Havstad Kris , Steenwerth Kerri , Chambers Jeanne , Deswood Helena , Kerr Amber , Rango Albert , Schwartz Mark , Stine Peter , Steele Rachel
Published: November 2020

This report describes the potential vulnerability of specialty crops, field crops, forests, and animal agriculture to climate-driven environmental changes. Here, vulnerability is defined as a function of exposure to climate change effects, sensitivity to these effects, and adaptive capacity. The exposure of specific sectors of the agricultural and forestry industries varies across the region because the Southwest is climatically and topographically diverse. There is also variability in the sensitivity of different systems to the effects of climate change. Most significantly, there is potential within agricultural and forestry systems to adjust to climate-related effects either through inherent resilience or through conservative management practices. The purpose of this analysis is to describe regional vulnerabilities to climate change and adaptive actions that can be employed to maintain productivity of working lands in the coming decades.
Adaptation Resources for Agriculture A Case Study: Organic Apple Orchard in Wisconsin
Authors: Dowling Adam
Published: November 2020

Working farm lands and specialty crop farms are an important and dominate
part of Wisconsin’s Driftless region providing a multitude of agricultural products and jobs. One of the many challenges facing the specialty crop producers in
this region and throughout the US is climate change. Brix Cider of Barneveld,
WI participated in the Adaptation Workbook* 5-step process to see if there are
ways for their operation to become more resilient in a changing climate.
Economics of Gully Erosion Stabilization
Authors: Knight Lynn , Hodgson Suzy
Published: November 2020

Rainfall intensity is increasing in the Northeastern U.S. Stabilizing gullies is one strategy for adapting
to this changing climate. This case study evaluates the costs and benefits of restoring gullies at Last
Resort Farm.
National Survey of USDA Field Staff on Climate and Weather
Authors: Wiener Sarah , Roesch-McNally Gabrielle , Schattman Rachel
Published: November 2020

In November/December of 2016, a survey collaboratively designed by the USDA Climate Hubs, FSA, and the University of Vermont was administered to capture FSA field staffs' beliefs and attitudes related to climate change and potential impacts, as well as their perceptions about the risk that weather variability poses for U.S. farmers.
Adaptation Resources for Agriculture: Responding to Climate Variability and Change in the Midwest and Northeast
Authors: Janowiak Maria , Dostie Daniel , Wilson Michael , Kucera Michael , Skinner Howard , Hatfield Jerry , Hollinger David , Swanston Christopher
Published: November 2020

Changes in climate and extreme weather are already increasing challenges for agriculture nationally and
globally, and many of these impacts will continue into the future. This technical bulletin contains information and resources designed to help agricultural producers, service providers, and educators in the Midwest and Northeast regions of the United States integrate climate change considerations and action-oriented decisions into existing farm and conservation plans. An Adaptation Workbook provides producers a flexible, structured process to identify and assess climate change impacts, challenges, opportunities, and farm-level adaptation tactics and continuously evaluate adaptation actions for improving responses to extreme and uncertain conditions. A synthesis of Adaptation Strategies and Approaches serves as a “menu” of potential responses organized to provide a clear rationale for making decisions by connecting planned actions to broad adaptation concepts. Responses address both short- and long-range timeframes and extend from incremental adjustments of existing practices to major alterations that transform the entire farm operation. Example adaptation tactics—prescriptive actions for agricultural production systems common in the region—for each approach guide producers, service
providers, and educators to develop appropriate responses for their farms and location. Four Adaptation
Examples demonstrate how these adaptation process resources are used.
Acél- és szintetikus makro szálak orientációja szálerősítésű betonban
Authors: Juhász Károly Péter
Published: November 2020

A szálerősítésű beton egy rövid szálas kompozit anyag, melynek tulajdonságai nagyban függnek a mátrixban elkevert szálak orientációjától. Kiindulásként a szálak egyenletes elkeveredését és ezáltal egyenletes orientációt feltételezünk, azonban a valóságban különböző hatások miatt ez nem teljesül. A szálak orientációjának egyenletestől való eltérése nagy hatással lehet az anyagparaméterekre, mind kedvező, mind kedvezőtlen irányban. Jelen cikkben az irodalomban fellelhető keverési modelleket hasonlítom össze kísérleti eredményekkel, és vizsgálom a betonozási mód, tömörítés, zsaluzat hatását acél és szintetikus makro szálak orientációjára.
Дослідження повздовжньої навантаженості несучої конструкції вагона-платформи зчленованого типу з пониженим центром ваги
Authors: Фомін О.В. , Ловська А.О. , Сапронова С.Ю.
Published: November 2020

Проведено визначення динамічної навантаженості несучої конструкції вагона-платформи зчленованого типу з пониженим центром ваги при експлуатаційних режимах. Враховано, що вагон-платформа завантажений двома великовантажними контейнерами типорозміру 1АА. Дослідження проведені в плоскій системі координат. Встановлено, що прискорення, які діють на несучу конструкцію першої з боку сили секції вагона-платформи складають 37,7 м/с², а другої – близько 38,6 м/с². Проведено розрахунок на міцність несучої конструкції вагона-платформи. Максимальні еквівалентні напруження при цьому виникають в зоні взаємодії хребтової балки зі шворневою та складають близько 300 МПа. Визначено поля розподілення прискорень відносно несучої конструкції вагона-платформи. Розбіжність між результатами математичного та комп’ютерного моделювання склала близько 13%. Проведені дослідження сприятимуть створенню нових конструкцій вагонів-платформ, а також підвищенню ефективності експлуатації комбінованих перевезень.
Contribution of Mathematical Anxiety, Learning Motivation and Self-Confidence to Student’s Mathematical Problem Solving
Authors: Irhamna Irhamna , Amry Zul , Syahputra Hermawan
Published: November 2020

The objectives of this study are to: (1) Analyze whether there is a contribution of mathematics anxiety, learning motivation and self-confidence to the ability to solve mathematical problems simultaneously, (2) Analyze whether there is a contribution of mathematics anxiety, learning motivation and self-confidence to the partial mathematical problem solving ability, (3) To analyze how big the contribution of mathematics anxiety, learning motivation and self-confidence to mathematical problem solving abilities simultaneously, (4) Analyze how much the contribution of mathematics anxiety, learning motivation and self-confidence to the partial mathematical problem solving abilit, (2) math anxiety questionnaire, (3) learning motivation questionnaire, (4) self-confidence questionnaire. Data analysis was performed by multiple linear regression analysis. The results showed: (1) There is a contribution to mathematics anxiety, learning motivation, and self-confidence to the ability to solve mathematical problems simultaneously, (2) There is a contribution to mathematics anxiety, learning motivation, and self-confidence to the ability to solve mathematical problems partially, (3) Mathematical anxiety, learning motivation and self-confidence contributed 26% to the ability to solve mathematical problems simultaneously, (4) Mathematical anxiety contributed 8.5% to mathematical problem solving abilities, learning motivation contributed 15.8% to mathematical problem solving abilities and self-confidence contributed 16.7% to mathematical problem solving abilities.
Correlation of Preoperative Nutritional Status and Postoperative Wound Infection in Children
Authors: Majumder Partha Sarathy , Karmaker Anuradha , Md Nooruzzaman - , Rahman Zahidur , Adil Syed Abdul , Alam Md Mahbubul
Published: November 2020

Background: Despite improvements in antimicrobial therapy, surgical technique and postoperative care, wound infection is still a major concern in pediatric surgical practice particularly in developing countries like Bangladesh.

Objective: This study was conducted to ascertain the relationship between the preoperative nutritional status and postoperative wound infection in children as malnutrition is very prevalent among them. It was also decided to estimate the rate of wound infection in children and to identify the indicator of malnutrition that best predicts wound infection.

Methods: This prospective study was carried out in the Department of Pediatric Surgery, BSMMU, Dhaka during the period of January 2009 to September 2010 and included consecutive 100 children undergoing routine surgery. Nutritional status was assessed by measuring BMI, serum albumin, haemoglobin and total lymphocyte count and thus children were categorized preoperatively. The children were assessed during the first 30 postoperative days for the evidence of wound infection that were confirmed by culture and sensitivity.

Results: We found most of the wound infections among the malnourished children with low BMI and low serum albumin.

Conclusion: Preoperative good nutritional status is associated with less postoperative wound infection and BMI and serum albumin are good indicators but total lymphocyte count and haemoglobin are not good indicators of protein calorie malnutrition and serum albumin is the best predictor of wound infection.

Journal of Surgical Sciences (2019) Vol. 23(2): 48-53
Costo-utilità di dalbavancina versus standard of care (SoC) in pazienti con ABSSSI non severa in Italia
Authors: Marcellusi Andrea , Bini Chiara , Rotundo Maria Assunta , Cultrera Rosario , Mennini Francesco Saverio
Published: November 2020

Introduction: Acute Bacterial Skin and Skin Structure Infections (ABSSSIs) include all complicated skin and soft tissue infections. The aim of this study was to conduct a cost-utility analysis to compare dalbavancin with standard antibiotic therapies for the management of non-severe ABSSSIs from the National Health Service (NHS) perspective.

Methods: A probabilistic decision tree model was developed considering a 30-days follow-up to simulate the therapeutic pathway of a patient treated with dalbavancin or Standard of Care (SoC). The model considered three mutually exclusive health states: a) discharge of patients from the emergency department, b) discharge of patients after one night from admission, c) discharge after 24 or 36 hours from admission. A one-way deterministic sensitivity analysis and a probabilistic sensitivity analysis were conducted.

Results: The analysis showed that the use of dalbavancin in patients with non-severe ABSSSI compared to SoC could generate a reduction in costs (– € 291.6 per patient treated) and an increase in QALYs (+0.0018 per patient treated). In 99.7% of the simulations carried out, dalbavancin was dominant compared to the SoC. Considering a threshold for the willingness to pay of € 30,000 for QALY gained, the minimum level of efficacy of dalbavancin so that the treatment can be considered cost-effective compared to the SoC was equal to 69.4%.

Conclusions: The analysis showed that dalbavancin may represent a cost-effective option compared to SoC for the treatment of patients with non-severe ABSSSI.
Analisis Bunyi dan Gaya Bahasa Nyanyian Rakyat
Authors: Mazhud Nurfathana
Published: November 2020

Menilik karya sastra dengan kajian stilistika dapat menonjolkan keindahan dan kekhasan bahasa yang digunakan penyair dalam kumpulan teks lagu bugis. Kemampuan penyair memilih kata bertujuan menimbulkan imajinasi pembaca dalam memahami ide dan gagasan yang terdapat dalam karya sastra elong ugi. Penelitian ini bertujuan untuk mendeskripsikan aspek-aspek stilistika nyanyian rakyat Bugis pada kumpulan teks elong ugi. Penelitian ini merupakan jenis penelitian deskriptif kualitatif dengan strategi grounded theory (teori dari bawah). Adapun metode yang digunakan dalam penelitian ini adalah metode deskriptif analisis. Hasil penelitian menunjukkan bahwa aspek-aspek stilistika nyanyian rakyat Bugis pada kumpulan teks elong ugi yakni pilihan kata, bahasa figuratif (majas), citraan (pengimajian), dan kata-kata konkret. Terdapat 7 lagu pada elong ugi tellujjori hurupukna yang dianalisis masih memiliki ciri khas yang kuat yakni jumlah setiap bait adalah 3 baris dan penggunaan aksara lontarak setiap bait yakni baris pertama 8, baris kedua 7, dan baris ketiga 6. Pada elong ugi sagala rupa ada 3 lagu yang dianalisis yang tidak terikat oleh baris dan bait lagi sehingga lagu tersebut digolongkan ke dalam  sastra modern.
Contribution to the knowledge on the flora of Mt. Luboten, Sharri Mts., Kosovo
Authors: Berisha Naim , Ćušterevska Renata , Millaku Fadil , Kostadinovski Mitko , Matevski Vlado
Published: November 2020

With the aim of improving the floristic knowledge of Kosovo, here we present an inventory of the plant taxa recorded and collected between the March 2015 and September 2019, in the mountain massif of Luboten, Sharri Mts., SE Kosovo. Field surveys were conducted repeatedly for four years, on each vegetation season. With this work we aimed to provide detailed data concerning the vascular flora richness and distributional patterns. Floristic samples were studied in all representative habitats and sites, concerning climate, exposition, altitude and bedrock composition. This research led to the identification of a total 853 plant taxa of vascular plants, belonging to 354 genera and 93 families. Among these taxa, 82 are Balkan endemics and 53 are included into the Red Book of Vascular Flora of Kosovo. Out of them, 4 are critically endangered, 16 endangered, 3 vulnerable, 8 near threatened and 22 least concern. On the basis of the available floristic literature, 2 plant taxa are found to be new for Kosovo: Bromopsis cappadocica subsp. cappadocica and Pilosella macrotricha. At a national scale, we have found new distribution records for 17 taxa and additionally for 2 plant taxa: Ranunculus fontanus and Sesleria wettsteinii, conservation suggestions are provided. All natural habitats were classified according to EUNIS and their floristic richness is herein provided. Furthermore, the corresponding EUNIS habitat(s) for each taxon of where it was recorded to be growing are also indicated.
STRAY PIN CAPACITANCE EFFECTS ON SIGNAL READING COUPLED BY OPTOCOUPLER ON MICROCONTROLLER BOARDS
Authors: Rumawas Albertus N , Sofyan Edi
Published: November 2020

Reading high frequency signal could have possibility effecter by the internalcapacitance from microcontroller pins. Study case is between Arduino and encoder couplerwith optocouplers. High frequency signal is struggle to high logic due to slower rise time.Turns out slower risetime caused by internal capacitance causing 1st order response system,by adding pull-up resistor on input pin, risetime could be reduce. As final result, addingpull-up resistor does affecting the rise time, but the there are still other factors besideinternal capacitance.
DESIGN AND SIMULATION OF ENGINE OPERATION TEMPERATURE MONITOR AND CONTROL SYSTEM BY USING INTERNET OF THING
Authors: Sembiring Joni Darlin , Baskoro Gembong , Berchmans Hanny J
Published: November 2020

In this thesis, it is explained how the development of an online monitoring engine temperature system that is connected with thingspeak. This system was designed and developed to monitor engine temperature. This system is made of several components, namely the Arduino Mega 2560 component which is connected to the LM35 heat sensor, LED, active buzzer, after which the data is stored in the database using the internet network. Data servers things that can be seen using a website besides that data can also be sent to customer users of mobile devices in this case will make the user easier because without opening the website the thingspeak will provide information if something is abnormal or when the temperature exceed standard
PRESSURE PATTERN IMPROVEMENT OF PROPORTIONAL VALVE APPLICATION ON HOT PRESS MACHINE USING PID
Authors: Stevanus Widianto , Berchmans Hanny J , Iskandar Aulia A
Published: November 2020

The purpose of this study is to develop a control scheme for the hydraulic proportionalsystem using PID function on Mitsubishi PLC Q series, which can rapidly control the pressurein a hydraulic cylinder with very short stroke. The mathematical model of the control system isestablished according to the principle of the electro-hydraulic system. Considering the mentionedcharacteristics, simulation of the system modelling will be established to know the systemresponse. In order to improve the control precision of the hydraulic hot-press system, theMitsubishi PID controller are designed by selecting appropriate tuning parameters. Their controlperformances are analysed in time domain respectively. The variation of PID controllerconfiguration will be conduct to know the better model for this system controller. The validityof the proposed control scheme is confirmed through the experiments to verify the rationality ofthe theoretical model. The results show that the Mitsubishi PID and the ideal PID give the sameresult for the tuning parameter resulted from simulation. And also the experiment give the betterstability in the 3 different pressure set value that conduct by author.
ACTUALIZATION OF THE JEAN PIAGET COGNITIVE DEVELOPMENT THEORY IN LEARNING
Authors: Sidik Firman
Published: November 2020

This article aims to look at Jean Piaget's actualization in the learning process, especially those related to theories about cognitive development. The method used in this research is literature review, the data of which is obtained from a variety of related literature, both directly and indirectly, which are studied with a theoretical and philosophical approach. The results of this study found that Jean Piaget's theory of cognitive development was quite influential in the world of education. In addition, in the process of education to get good results all components, especially educators must adjust to the development of students, and should always give an appreciation of all forms of positive actualization of students so that it has an impact on the cognitive development of students.
THE USE OF SOCIAL MEDIA AS EFFECTIVE LEARNING MEDIA DURING THE COVID-19 PANDEMIC
Authors: Hapsari Sri
Published: November 2020

This exploratory article is concerned with the utilization of social media platforms as learning media during the covid-19 pandemic. The Indonesian government issued a policy to work at home, study at home, and worship at home during the pandemic. Several social media applications have become popular among Indonesians during the pandemic. This study explored several students’ learning process using social media. The findings show the diversity of social media chosen by students based on their level of needs and economic factors.
Analisis Komunikasi Verbal Konselor Sebaya Dalam Melakukan Layanan Konseling Berbasis Daring
Authors: Melitawati Meliyawati Meliyawati , Sari Ajeng Mulia
Published: November 2020

Penyelenggaraan layanan konseling  sebaya berbasis daring dilakukan oleh mahasisewa BK UNMA selama 2 pekan. Layanan dibuka dengan menggunakan  beberapa media social. Layanan konseling sebaya berbasis daring  Pelayanan Konseling  sebaya berbasis daring ini mengutamkan proses  komunikasi  antarpribadi yang berlangsung melalui saluran komunikasi . Teknik verbal ajakan untuk memulai, penerimaan, refleksi pikiran, refleksi perasaan, klarifikasi pikiran, klarifikasi perasaan, permintaan untuk melanjutkan, pengulangan satu-dua kata, dan rangkuman mengandungpengarahan sedikit dan lebih sesuai dengan metode nondirektif, sedangkan pertanyaan mengenai hal tertentu, pemberian umpan balik, pemberian informasi, penyajian alternatif, penyelidikan, pemberian struktur, interpretasi, konfrontasi, diagnosis, dukungan, usul/saran, dan penolakan mengandung pengarahan banyak dan lebih sesuai dengan metodedirektif. Tinjauan khusus penelitian ini yaitu, pertama Bagaimana hasil layanan konseling sebaya berbasis daring, dan kedua Bagaimana hasil analisis komunikasi verbal konselor sebaya dari hasil isi layanan konseling sebaya berbasis daring. Metode penelitian yang digunakan adalah penelitian Kualitatif dengan pendekatan deskriptif analisi. Penelitian kualitatif adalah sebagai prosedur penelitian yang menghasilkan data deskriptif berupa kata-kata tertulis atau lisan dengan orang yang perilaku yang dapat diamati.Dari hasil analisis komunikasi verbal konselor sebaya saat melakukan layanan konseling berbasis daring konselor banyak menggunakan tehnik komunikasi verbal berupa ;  ajakan untukmemulai, penerimaan/menunjukkanpengertian, refleksipikiran, refleksiperasaan, klarifikasi pesan, pemberian umpanbalik, penyajianalternatif, penyelidikan, interpretasi, diagnosis, dukungan/bombongan, usul/saran. Tehnik ini dilakukan sesuai dengan permasalahan yang dihadapi klien yang dominan berkaitan dengan kepercayaan diri / insecure, permasalahan terakit keluarga dan pekerjaan
Génmódosított immunsejtek: új fegyverek nem csak daganatok ellen
Authors: Szöőr Árpád
Published: November 2020

Az elmúlt évtized onkológiai áttörése minden bizonnyal a CD19-specifikus CAR T-sejtek alkalmazása volt a különböző hematológiai kórképek kezelésében. A klinikai vizsgálatokban szerzett tapasztalatok, pá­ro­sulva a magánszektor és gyógyszeripar befektetéseivel, a meglévő CAR T-sejt-ké­szítmények kereskedelmi forgalmazásával, sok kutató figyelmét irányította rá az új típusú immunsejtekben rejlő lehetőségekre, és azok nem onkológiai célú fel­hasz­ná­lására. A közlemény célkitűzése, hogy rö­viden bemutassa azokat a preklinikai alkalmazásokat, ahol a CAR T-sejteket sikerrel próbálták ki autoimmun és infektológiai kórképekben.
Potential of nicergoline in polymorbidity and cognitive impairment (clinical case)
Authors: Ostroumova O. D. , Kochetkov A. I. , Ostroumova T. M. , Klepikova M. V.
Published: November 2020

In real clinical practice, the problem of polymorbidity and, in particular, its cardiometabolic phenotype, is now widespread. One of the its variants is a combination of arterial hypertension with diabetes mellitus, overweight, cognitive impairment, and peripheral atherosclerotic arterial disease. The clinical significance of such polymorbidity portrait, on the one hand, lies in its frequent occurrence, and, on the other hand, in the cardiovascular risk amplification in the settings of simultaneous coexistence of diseases initially characterized by an extremely unfavorable prognosis for the patient. The article presents a clinical case of a patient with a such polymorbidity variant and considers the nicergoline potential in the complex correction of mutually associated comorbidities. The nicergoline ability to improve cognitive functioning, to have a beneficial effect on peripheral circulation, which is reflected in an increase in the distance of painless walking, and also to realize some antihypertensive effect has been demonstrated. No less important is the fact that the high therapeutic efficacy of nicergoline was combined with an optimal safety profile, which consists in good tolerability of therapy and the absence of adverse drug reactions.
Metabolic therapy for comorbid pathology
Authors: Vertkin A. L. , Sycheva A. S. , Nosova A. V. , Knorring G. U. , Zavyalov G. V.
Published: November 2020

Demographic changes, the increasing frequency of comorbidity make us pay close attention to the prescribed therapy andcontrol of drug to drug interactions. The use of polymodal drugswith pleiotropic effects that affect the key points of developmentof comorbid pathology may be promising.
IMPROVING THE EFFICIENCY INTO THE IMPACT FLUID FRACTURING BY ADAPTING IT TO THE PARAMETERS OF THE ENCLOSING ENVIRONMENT
Authors: Kyu Nikolai G.
Published: November 2020

The principle of formation of the oriented crack by displacement of a plastic substance from the well in the mode providing coincidence of frequency of influence on a plastic substance and natural frequency of oscillations of the host medium is discussed. The technical solution of adaptation of the mode of injection of a plastic substance into the formed crack to the changing parameters of the host medium is given. The means of implementation of this technical solution and the results of engineering calculations of their main components are presented.
TO THE ESTIMATE OF STRESS-STRAIN STATE OF THE ROCK MASS IN THE NIZHNEKANSKY REGION
Authors: Leontyev Arkady V. , Rubtsova Yekaterina V. , Skulkin Aleksandr A.
Published: November 2020

Practical geomechanics is based on an integrated approach, which assumes involving the results of geological, seismological, geophysical and other observations in order to increase the reliability of analytical solutions and to ensure the completeness and quality of interpretation of instrumental control data. The paper provides an example of the implementation of such an approach. When assessing the stress-strain state of the Nizhnekansky region, information on the geological characteristics of the object, as well as data on seismicity and seismotectonic deformations of the Earth’s crust in the Altai - Sayan region and Baikal rift zone were used. As a result of a systematic integrated analysis of geological and seismotectonic information, it was found that junction of the Siberian platform and the West Siberian plate in the area of Nizhnekansky granitoid massif should be related to a region with an average degree of tectonic activity. The territory of the right bank of the Yenisei is characterized by a regional compression field of near-latitudinal orientation. The results of instrumental stress control by hydraulic fracturing method in local zones of the rock mass at a depth of 260 m are presented. It is determined that the rock mass has a significant margin of safety with respect to the parameters of active stress field.
INCREASING THE SELECTIVITY OF USEFUL MINERAL DISCLOSURE WHEN PROCESSING DIFFICULT POLYMINERAL RAW MATERIALS WITH PRELIMINARY WEAKENING
Authors: Rostovtsev Viktor I. , Kondratyev Sergey A.
Published: November 2020

Previous studies at a number of research centers in our country, including the Institute of Mining, SB RAS and the Institute of Nuclear Physics, SB RAS, showed the possibility of improving process parameters of flotation concentration of difficult mineral raw materials due to preliminary electron-beam processing, which allows weakening minerals and rocks. Obtaining the data on selective disintegration and disclosure of minerals during ore pretreatment is important for technological application. This study aims at receiving the experimental data confirming an increase in the selectivity of disintegration of mineral raw materials processed by a high-energy electron beam and an improvement in the disclosure of intergrowths of useful minerals. Complex experimental mineralogical and technological studies by the example of rebellious lead-zinc ore with a grain size of -3 mm provided the data on increasing the selectivity of disintegration of mineral raw materials and improving the disclosure of useful minerals. It is found that if in -0.071 mm size class of ground lead-zinc ore without processing, the fraction of free galena and wurtzite grains (sphalerite modification) is 40.7 and 65.7%, then the fraction of free grains of these minerals increases up to 66, 4 and 71.5% in ore pretreatment. It should be noted that ore processing by accelerated electrons allows obtaining the ground material, in which free mineral grains are less overground. For galena, the size of free grains increases from 2.6 to 4.0 μm, and for wurtzite - from 4.5 to 6.6 μm. Scientific novelty includes increasing the selectivity of disintegration and improving the disclosure of useful minerals through the effect of weakening of mineral raw materials in ore pretreatment.
DETERMINATION OF STRESS-STRAIN STATE OF THE BODY SURFACE OR ITS AREA IN CASE OF PERFECT PLASTICITY AT GIVEN STRESS AND DISPLACEMENT VECTORS
Authors: Chanyshev Anvar I. , Abdulin Ilgizar M. , Lukyashko Olga A.
Published: November 2020

Ideally plastic state of material under conditions of Mises plasticity, proportionality of stress and strain deviators (deformation theory of plasticity) and elastic volume change is considered. Given the Cauchy stress and displacement vectors specified on the body surface (with indicated state) or its area, all six components of the stress tensor, all six components of the strain tensor, and also three components of the rotation vector are restored on this surface. This method for determining the stress-strain state can be related to the methods of rapid assessment of the structure state (body surface), since differential equations inside the body are not involved.
COAL PERMEABILITY ANISOTRTOPY ESTIMATION BY FILTRATION EXPERIMENTS AND FRACTURE ANALYSIS RESULTS
Authors: Shilova Tatyana V. , Rybalkin Leonid A. , Yablokov Alexander V.
Published: November 2020

Experimental studies of the structure of medium-volatile bituminous coal taken from the Leninsk region of Kuzbass are performed. The main properties of endogenous cleavage fractures are determined. The dependence of coal absolute permeability on uniform compression of samples is experimentally explored. Laboratory permeability tests were conducted in the direction parallel to master cleavage fractures and bedding planes. The obtained values are typical for intensely fractured coals. Using the known models, the dependence of coal permeability on stress conditions is obtained for the directions parallel to master and side cleavage. The anisotropy of coal horizontal permeability is determined taking into account the properties of endogenous cleavage fractures. Change in coal permeability with seam depth is estimated in conditions of the Leninsk region of Kuzbass. The permeability-depth data were obtained for the conditions of uniaxial strain perpendicular to layered structure and endogenous cleavage planes.
EXPERIMENTAL DETERMINATION OF THE PARAMETERS OF LOW FREQUENCY FILTERS FOR PROTECTING HONEYWELL ML PRESSURE SENSORS FROM DYNAMIC LOADS IN STUDYING HYDROIMPULSE SYSTEMS
Authors: Gorodilov Leonid V. , Kudryavtsev Vitaly G. , Pershin Aleksei I.
Published: November 2020

The design of a low-frequency hydraulic filter including a throttle with a calibrated hole and a fixed volume of liquid is presented. The filter was tested when studying the working cycles of a hydraulic impact device. Using Kistler 6001 pressure sensor, the frequency characteristics of the filter with throttles having hole diameters of 0.4, 0.6, 0.8, 1, 1.6 mm were determined and their parameters ensuring the protection of sensors and required measurement accuracy were selected.
METHOD TO REDUCE COUNTER PRESSURE IN FRONT CHAMBER OF HUMMERS WITH A HYDRAULIC BACK STROKE CHAMBER
Authors: Danilov Boris B. , Rechkin Aleksandr A.
Published: November 2020

Using the simulation model, the occurrence of significant counter pressure to striker movement during the power stroke in hummers with a hydraulic back stroke chamber is shown. A device (spring pressure reducing valve) is proposed, which allows decreasing the pressure of resistance to the striker movement. The comparative energy characteristics of a hummer with such a device and machine with standard discharge are obtained, technical parameters of both machines are similar.
EFFECT OF ORIGINAL STRESS STATE OF THE ROCK MASS ON DISTRIBUTION OF DISPLACEMENTS AND STRESSES IN THE VICINITY OF SUPPORTED MINE WORKING IN UNSTABLE ROCKS
Authors: Krasnovsky Andrey A. , Seryakov Viktor M.
Published: November 2020

The statement of the problem of finding the stress-strain state of support and rocks surrounding the mine working in case of cushioning with phenol resins is used to determine the peculiarities of its formation under the influence of gravitational and hydrostatic original stress fields. It is found that maximum vertical compressive stresses arise in vertical support units at gravitational field, which exceed by half their values for a hydrostatic field. However, as the height in the mine roof filled with phenol resins increases, maximum vertical stresses for both options become comparable. In arch support units at hydrostatic original state of the rock mass, the values of horizontal tensile stresses are by half less than at gravitational original field.
Representações sociais da formação do graduado em Moda por empresários do setor
Authors: Rodrigues Rose Mary Mariano , Lima Rita de Cássia Pereira
Published: November 2020

O objetivo do estudo é investigar representações sociais da formação do graduado em Moda por empresários do setor no Rio de Janeiro. A pesquisa fundamentou-se na Teoria das Representações Sociais (TRS) e em estudos do campo da moda. Foram entrevistados 20 empresários de moda, sendo 10 com formação em Moda (Grupo 1) e 10 sem essa formação (Grupo 2). O material das entrevistas foi analisado com apoio da análise de conteúdo temática, complementada com repostas às seguintes questões: 1) “Se você fosse diretor (a) de uma escola de formação em Moda, como seria o seu curso? ”; e 2) “O que vem à sua mente quando eu digo ‘primeira imagem do graduado em Moda’? ”. A análise do conjunto desse material permitiu a proposição de um modelo figurativo da representação social da formação do graduado em Moda para cada um dos grupos. Para o Grupo I, a representação se objetiva em “insuficiência na formação do graduado em Moda” e para o Grupo 2 em “aprendizagem acontece no mundo do trabalho”, podendo por vezes prescindir da formação acadêmica. Os resultados apontaram para o pouco diálogo entre cursos de graduação em Design de Moda e o empresariado do setor, contudo, mostraram possibilidades de aproximação entre essas duas áreas, universidade e mundo do trabalho.
Bacterial Infection in etiology of Pigment Gallstones
Authors: Wani Rauf Ahmad
Published: November 2020

Brown pigment stones are an important cause of acute cholangitis in Oriental Cholangiohepatitis. Bacterial infection and the deconjugation of bile by bacterial b-Glucourindase have been implicated as etiological factors in formation of brown pigment stones but controversy exists regarding their primary importance and causal relationship.
Cross-Entropy Method in Application to the SIRC Model
Authors: Stachowiak Maria Katarzyna , Szajowski Krzysztof Józef
Published: November 2020

The study considers the usage of a probabilistic optimization method called Cross-Entropy (CE). This is the version of the Monte Carlo method created by Reuven Rubinstein (1997). It was developed in the context of determining rare events. Here we will present the way in which the CE method can be used for problems of optimization of epidemiological models, and more specifically the optimization of the Susceptible–Infectious–Recovered–Cross-immune (SIRC) model based on the functions supervising the care of specific groups in the model. With the help of weighted sampling, an attempt was made to find the fastest and most accurate version of the algorithm.
Does Stewardship Theory Provide a Viable Alternative to Control-Fixated Performance Management?
Authors: Torfing Jacob , Bentzen Tina Øllgaard
Published: November 2020

Stewardship theory provides an interesting alternative to agency theory, which in the recent New Public Management era supported the introduction of rigorous performance management systems based on generalized mistrust in and control of public employees. However, we lack empirical validation of the feasibility and positive outcomes of the new forms of trust-based management recommended by stewardship theory. As such, there are few examples of alternative ways of boosting the motivation of public employees that can serve as beacons for public service organizations (PSOs) eager to find new ways of motivating their staff to create public value for the users of public services and society as a whole. This article aims to remedy this problem by exploring a seemingly successful empirical case of trust-based management to see whether the core principles of stewardship theory apply and how new management practices may influence the motivation and well-being of the employees, the perceived satisfaction and involvement of the users, and overall organizational performance, including cost efficiency.
Tillage, Glyphosate and Beneficial Arbuscular Mycorrhizal Fungi: Optimising Crop Management for Plant–Fungal Symbiosis
Authors: Wilkes Thomas I. , Warner Douglas J. , Davies Keith G. , Edmonds-Brown Veronica
Published: November 2020

Zero till cropping systems typically apply broad-spectrum herbicides such as glyphosate as an alternative weed control strategy to the physical inversion of the soil provided by cultivation. Glyphosate targets 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase in plants. There is growing evidence that this may have a detrimental impact on non-target organisms such as those present in the soil microbiome. Species of commercial importance, such as arbuscular mycorrhizal (AM) fungi that form a symbiotic relationship with plant roots are an important example. This study investigates the impact of soil cultivation and glyphosate application associated with conventional tillage (CT) and zero tillage (ZT) respectively on AM fungi populations under field and glasshouse conditions. Topsoil (<10 cm) was extracted from CT and ZT fields cropped with winter wheat, plus non-cropped control plots within the same field boundary, throughout the cropping year. Glyphosate was applied in glasshouse experiments at rates between 0 and 350 g L−1. Ergosterol, an indicator of fungal biomass, was measured using high performance liquid chromatography before and after glyphosate application. Fungal root arbuscules, an indicator of AM fungi–root symbiosis, were quantified from the roots of wheat plants. Under glasshouse conditions root arbuscules were consistently higher in wheat grown in ZT field extracted soils (P = 0.01) compared to CT. Glyphosate application however inhibited fungal biomass in both the ZT (P < 0.00001) and CT (P < 0.001) treatments. In the absence of glyphosate, the number of stained root arbuscules increased significantly. Ergosterol levels, used as a proxy for fungal biomass, remained lower in the soil post glyphosate application. The results suggest that CT has a greater negative impact on AM fungal growth than ZT and glyphosate, but that glyphosate is also detrimental to AM fungal growth and hinders subsequent population recovery.
Evaluation of Nitrogen Fertilization Systems Based on the in-Season Variability in the Nitrogenous Growth Factor and Soil Fertility Factors—A Case of Winter Oilseed Rape (Brassica napus L.)
Authors: Grzebisz Witold , Łukowiak Remigiusz , Kotnis Karol
Published: November 2020

Application of nitrogen (N) in contrastive chemical form changes availability of soil nutrients, affecting crop response. This hypothesis was evaluated based on field experiments conducted in 2015/16 and 2016/2017. The experiment consisted of three nitrogen fertilization systems: mineral-ammonium nitrate (AN) (M-NFS), organic-digestate (O-NFS), 2/3 digestate + 1/3 AN (OM-NFS), and N rates: 0, 80, 120, 160; 240 kg ha−1. The content of nitrogen nitrate (N-NO3) and available phosphorus (P), potassium (K), magnesium (Mg) and calcium (Ca) were determined at rosette, onset of flowering, and maturity of winter oilseed rape (WOSR) growth from three soil layers: 0.0–0.3, 0.3–0.6, 0.6–0.9 m. The optimum N rates were: 139, 171 and 210 kg ha−1 for the maximum yield of 3.616, 3.887, 4.195 t ha−1, for M-NFS, O-NFS, OM-NFS. The N-NO3 content at rosette of 150 kg ha−1 and its decrease to 48 kg ha−1 at the onset of flowering was the prerequisite of high yield. The key factor limiting yield in the M-NFS was the shortage of Ca, Mg, O-NFS—shortage of N-NO3. Plants in the OM-NFS were well-balanced due to a positive impact of the subsoil Mg and Ca on the N-NO3 content and productivity. The rosette stage was revealed as the cardinal for the correction of WOSR N nutritional status.
Assessment of Total Antioxidant Capacity in Serum of Heathy and Stressed Hens
Authors: Cecchini Stefano , Fazio Francesco
Published: November 2020

Total antioxidant capacity (TAC) in healthy and dexamethasone-stressed hens was measured by applying four different spectrophotometric methods—the ferric reducing ability (FRAP) assay, the 2,2′-azino-bis (3-ethylbenzotiazoline-6-sulphonic acid) (ABTS) radical cation decolorization assay, the free radical scavenging activity (FRSA), and the total thiol levels (TTL). TAC assessed by all four methods did not change throughout the experimental period in the control group, whereas significant changes were shown by all adopted assays in the stressed group with some remarkable differences. TAC increased in the stressed group when FRAP and ABTS assays were applied, while it was reduced when sera were assessed by FRSA and TTL assays. Furthermore, FRAP assay was the only test able to show a significant change in TAC immediately after the end of the induced stress. At the end of the experimental period, TAC assessed by ABTS and FRSA assays showed a complete recovery in the stressed group, whereas TAC assessed by FRAP and TTL assays still showed significant persistent differences when compared to the control group. The observed differences in TAC are discussed in the light of the different contribution in each assay of the various antioxidant substances present in the samples.