bluuebunny/crossref_metadata_2025 huggingface dataset:
Algorithmic Spaced Retrieval Enhances Long-Term Memory in Alzheimer Disease: Case-Control Pilot Study (Preprint)
Authors: Smith Amy M , Marin Anna , DeCaro Renee E , Feinn Richard , Wack Audrey , Hughes Gregory I , Rivard Nathaniel , Umashankar Akshay , Turk Katherine W , Budson Andrew E
Published: July 2024

BACKGROUND

Spaced retrieval is a learning technique that involves engaging in repeated memory testing after increasingly lengthy intervals of time. Spaced retrieval has been shown to improve long-term memory in Alzheimer disease (AD), but it has historically been difficult to implement in the everyday lives of individuals with AD.

OBJECTIVE

This research aims to determine, in people with mild cognitive impairment (MCI) due to AD, the efficacy and feasibility of a mobile app that combines spaced retrieval with a machine learning algorithm to enhance memory retention. Specifically, the app prompts users to answer questions during brief daily sessions, and a machine learning algorithm tracks each user’s rate of forgetting to determine the optimal spacing schedule to prevent anticipated forgetting.

METHODS

In this pilot study, 61 participants (young adults: n=21, 34%; healthy older adults: n=20, 33%; people with MCI due to AD: n=20, 33%) used the app for 4 weeks to learn new facts and relearn forgotten name-face associations. Participation during the 4-week period was characterized by using the app once per day to answer 15 questions about the facts and names. After the 4-week learning phase, participants completed 2 recognition memory tests approximately 1 week apart, which tested memory for information they had studied using the app as well as information they had not studied.

RESULTS

After using the mobile app for 1 month, every person with MCI due to AD demonstrated improvements in memory for new facts that they had studied via the app compared to baseline (P<.001). All but one person with MCI due to AD (19/20, 95%) showed improvements of more than 10 percentage points, comparable to the improvements shown by young adults and healthy older adults. Memory for name-face associations was similarly improved for all participant groups after using the app but to a lesser degree. Furthermore, for both new facts and name-face associations, we found no memory decay for any participant group after they took a break of approximately 1 week from using the app at the end of the study. Regarding usability, of the 20 people with MCI due to AD, 16 (80%) self-adhered to the app’s automated practice schedule, and half of them (n=10, 50%) expressed an interest in continuing to use it.

CONCLUSIONS

These results demonstrate early evidence that spaced retrieval mobile apps are both feasible for people with early-stage AD to use in their everyday lives and effective for supporting memory retention of recently learned facts and name-face associations.
AI: Bridging Ancient Wisdom and Modern Innovation in Traditional Chinese Medicine (Preprint)
Authors: Lu Linken , Lu Tangsheng , Tian Chunyu , Zhang Xiujun
Published: July 2024

UNSTRUCTURED

The pursuit of groundbreaking health care innovations has led to the convergence of artificial intelligence (AI) and traditional Chinese medicine (TCM), thus marking a new frontier that demonstrates the promise of combining the advantages of ancient healing practices with cutting-edge advancements in modern technology. TCM, which is a holistic medical system with >2000 years of empirical support, uses unique diagnostic methods such as inspection, auscultation and olfaction, inquiry, and palpation. AI is the simulation of human intelligence processes by machines, especially via computer systems. TCM is experience oriented, holistic, and subjective, and its combination with AI has beneficial effects, which presumably arises from the perspectives of diagnostic accuracy, treatment efficacy, and prognostic veracity. The role of AI in TCM is highlighted by its use in diagnostics, with machine learning enhancing the precision of treatment through complex pattern recognition. This is exemplified by the greater accuracy of TCM syndrome differentiation via tongue images that are analyzed by AI. However, integrating AI into TCM also presents multifaceted challenges, such as data quality and ethical issues; thus, a unified strategy, such as the use of standardized data sets, is required to improve AI understanding and application of TCM principles. The evolution of TCM through the integration of AI is a key factor for elucidating new horizons in health care. As research continues to evolve, it is imperative that technologists and TCM practitioners collaborate to drive innovative solutions that push the boundaries of medical science and honor the profound legacy of TCM. We can chart a future course wherein AI-augmented TCM practices contribute to more systematic, effective, and accessible health care systems for all individuals.
Comparing the Prognostic Roles of Red Blood Cell Volume Distribution Width, Neutrophil–Lymphocyte Ratio, and Platelet–Lymphocyte Ratio for Predicting Mortality after Hip Fracture in the Geriatric Population (Preprint)
Authors: Su Yu-Hsiang , Huang Yen-Wei , Huang Shu-Wei , Kuo Yi-Jie , Chuang Tai-Yuan , Chen Yu-Pin
Published: July 2024

BACKGROUND

Hip fractures have adverse effects on older adults, often resulting in reduced functional independence, increased social costs, morbidity, and an elevated risk of mortality within 1 year after surgery. Prognostic markers such as red blood cell volume distribution width (RDW), the neutrophil–lymphocyte ratio (NLR), and the platelet–lymphocyte ratio (PLR) have been used to predict outcomes following hip fracture surgery; however, their prediction accuracy has varied across studies.

OBJECTIVE

This study aims to compare the prognostic accuracy of RDW, NLR, and PLR in predicting the mortality of older adults after hip fracture surgery.

METHODS

This study enrolled 469 patients who underwent hip fracture surgery and were followed up for 1 year at a single tertiary medical center from December 2018 to May 2022. The patients’ preoperative RDW, NLR, and PLR levels were measured, and data on their clinical characteristics were collected. Receiver operating characteristic (ROC) curves and areas under the curve (AUCs) were used to assess the predictive accuracy of these markers for 1-month, 3-month, and 1-year mortality.

RESULTS

Among the patients, the mean age was 81.2 years, and 2.6%, 4.1%, and 13.9% died within 1 month, 3 months, and 1 year after surgery, respectively. RDW, NLR, and PLR were nonsignificant predictors of 1-month mortality, but RDW was the sole significant predictor of 3-month and 1-year mortality. The cutoff values for RDW were 15.05% and 13.65% for 3-month and 1-year mortality, respectively. Among the patients aged 60–80 years, RDW was a significant predictor of mortality following hip fracture surgery (AUC: 1 month, 0.83; 3 month, 0.86). However, for the patients aged >80 years, all three markers were nonsignificant predictors.

CONCLUSIONS

RDW was a robust prognostic factor that outperformed NLR and PLR in predicting the mortality of patients aged >60 years who underwent hip fracture surgery. Furthermore, the predictive accuracy of RDW was even higher for 1-month and 3-month mortality of patients aged 60–80 years who underwent hip fracture surgery.
Risk Factors of Asymptomatic Kidney Stone Passage in Adults with Recurrent Kidney Stones
Authors: Stritt Kevin , Fuster Daniel G. , Dhayat Nasser A. , Bonny Olivier , Faller Nicolas , Christe Andreas , Taha Anas , Ochs Vincent , Ortlieb Niklas , Roth Beat ,   on behalf of the NOSTONE Study
Published: July 2024

Key Points

Asymptomatic stone passage was common in patients with recurrent calcium-containing kidney stones.

Higher the number of stones at presentation, more likely it was that a kidney stone would spontaneously pass over time without causing any symptoms.

Background

Kidney stones are a common health problem and are characterized by a high risk of recurrence. A certain number of kidney stones pass asymptomatically. Data regarding the frequency of asymptomatic spontaneous stone passages are limited.

Methods

To assess the frequency of asymptomatic spontaneous stone passage and its covariates, we conducted a post hoc analysis of the prospective randomized NOSTONE trial. All asymptomatic spontaneous stone passages were identified by comparing the total number of kidney stones on low-dose noncontrast computed tomography (CT) imaging at the beginning and end of the study, considering symptomatic stone passages and surgical stone removal. The statistical analysis focused on the association of independent variables and the number of asymptomatic spontaneous stone passages using linear regression analyses.

Results

Of the 416 randomized patients, 383 with both baseline and end-of-study CT were included in this analysis. The median follow-up period was 35 months, the median patient age was 49 years (interquartile range [IQR], 40–55), and 20% of the patients were female. A total of 442 stone events occurred in 209 of 383 (55%) patients: 217 of 442 (49%) were symptomatic spontaneous stone passages, 67 of 442 (15%) were surgically removed stones, and 158 of 442 (36%) were asymptomatic spontaneous stone passages. The median size of asymptomatic stones (2.4 mm; IQR, 1.95–3.4) and the size of symptomatic stones (2.15 mm; IQR, 1.68–2.79) that passed spontaneously were not significantly different (P = 0.37). The number of asymptomatic spontaneous stone passages was significantly associated with a higher number of stones on CT at randomization (P = 0.001). Limitations include the lack of data on stone size at the time of passage and overrepresentation of White men.

Conclusions

Asymptomatic stone passage was common in patients with recurrent calcium-containing kidney stones. The higher the number of stones at presentation, the more likely it was that a kidney stone would spontaneously pass over time without causing any symptoms.

Clinical Trial registry name and registration number:

NOSTONE trial and: NCT03057431.
A Legal Evaluation of Companies Income Tax Under the Nigerian Tax Regime
Authors: Agwor, Ph.D Desmond O. N. , Agwor, Ph.D Charles I. G.
Published: July 2024

The paper examined the legal evaluation of Companies Income Tax (CIT), its Practice, Enforcement and Effects in Nigeria. The conceptual clarification of the key concepts were considered and a comprehensive introduction of the companies income tax practice in Nigeria was reiterated. Amongst the key terms considered were company, income, tax and companies income tax respectively. It highlighted the legal history and imposition of companies income tax in Nigeria, prior, during and postcolonial era until the present day legal regime. In the same vein, administration of companies income tax in Nigeria was critically evaluated, including the classification of companies income tax, taxable companies and taxable profits respectively. Furthermore, the paper emphasized on the enforcement of companies income tax in Nigeria and elucidated on the importance and challenges of enforcement of companies income tax in Nigeria, which includes tax evasion and under declaration of income and profits in order to reduce amount of taxable profits. The paper was summarized with a conclusion.
The Islamic Feminism Object-Oriented and The Postcolonial Frameshift Mutation in the Intercommunicating Postmodernism Frame of Reference In Nawal El Saadawi’s The Fall Of The Imam
Authors: DIALLO SOULEYMANE
Published: July 2024

One of the most striking outcomes, one can see through the run of Nawal El Saadawi’s The Fall Of The Imam, is that the feminine reflexive consciousness within the feminine self becomes at the same time, the subject and the object of her inner being, and her straight apperception. Therefore, by moving away from the phallocentric traditional nominalism, the notion of equity that sustains the feminine reflexive consciousness involves a new method of politico-theological discourse and defines a neo-politico-fiction and scientific perception. In this realm, the feminine focus on the essence of al-ta’aruf and al-tafakhur exhibits a feminine psycho-affective that involves itself in the long-male reserved Tawhidic sphere, in perspective to embody the performativity and the ethic of Khalifah. Correspondingly, throughout psychobiological and psychodynamic interoperability, the feminine reflexive consciousness opens the sphere of familiarizing the feminine-self progressive intellectualization of sensation and the reflexive production of values and rhythms with the meta-cultural and moral interpretation of the Islamic texts. In effect, by accentuating their phallocentric-designated avatar of fitna, the feminine reflexive consciousness disperses the Muslim conservative object-relation normativism.
The Impact of AI on Improving the Efficiency and Accuracy of Managerial Decisions
Authors: Shukla Mr. Mayank
Published: July 2024

Abstract: This research investigates the profound impact of Artificial Intelligence (AI) on the efficiency and accuracy of managerial decision-making. As businesses navigate increasingly complex and dynamic environments, AI technologies have emerged as crucial tools for enhancing decision-making processes. This study explores various AI applications that assist managers in data analysis, forecasting, and strategic planning, demonstrating how AI can lead to more informed, timely, and precise decisions. By examining case studies and analyzing empirical data, the research highlights the transformative potential of AI in the realm of managerial decision-making
Development of multimedia-based learning videos to increase learning motivation in history for grade XI social science students in senior high school
Authors: Romualdi Kristoforus Bagas , Sudrajat Ajat
Published: July 2024

Students' motivation during history learning processes in the classroom is influenced, among other factors, by teachers' innovation in teaching. However, there are still teachers who lack innovation, resulting in decreased motivation for students to learn history. This study aims to develop and assess the feasibility of a product in the form of multimedia-based learning videos on the topic of Islamic Maritime Kingdoms, as well as to analyze its effectiveness in increasing the learning motivation of Grade XI Social Science students. The type of research used was research and development with ADDIE design. This study involved 2 experts, 2 teachers, and 75 students divided into 15 students for small-scale trials and 60 students for large-scale trials and extensive testing. Data collection was done through questionnaires using survey techniques and interviews. Data analysis techniques included quantitative and qualitative descriptive analysis, as well as descriptive statistics. The research results indicated that the product developed by the researcher was feasible for use as a learning media. Additionally, multimedia-based learning videos were also effective in increasing students' motivation to learn history.
Development of Historical Comic Strip Learning Media in Indonesian National Movement Materials
Authors: Aryasaha Dhoni Frizky , Suryadi Andy
Published: July 2024

The study aims to (1) analyze the conditions of history learning at SMA N 12 Semarang, (2) describe the development of historical comic strip learning media, and (3) analyze the feasibility of historical comic strip learning media. The research uses the Research and Development with a modification of the 4D development model. Several stages are passed in this research, including definition, design, and development. The results of this research are (1) students need learning media, (2) development of historical comic strip learning media in Indonesian National Movement materials entitled “Story of Athar” with manual sketches, digitalization, and digital coloring until finalization, (3) feasibility validation product, namely 94% from material experts, 96% from media experts. The effectiveness of learning media in increasing students’ interest in learning is obtained from the results of the gain score using the formula for the difference between pre-test and post-test scores of 32,26%. Based on the results of this research, the scores of increasing students’ interest in learning in class XI F 11 are included in the High category because the gain score is 0,767 and is in the range g > 0,7.
O ESTADO DA ARTE SOBRE APRENDIZAGEM COLABORATIVA APLICADA AO ENSINO DE CIÊNCIAS NO CONTEXTO DO ENSINO MÉDIO
Authors: Almeida Rodrigo dos Santos , Alves Telma , Pereira Marcus Vinícius da Silva , Rôças Giselle
Published: July 2024

Neste artigo, temos como objetivo realizar um estado da arte em artigos, dissertações e teses sobre aprendizagem colaborativa aplicada ao ensino de ciências, publicados em língua portuguesa, com foco no ensino médio. Para tal, fizemos uso do BUSCAd, um buscador acadêmico em forma de planilha com diferentes funcionalidades para realizar uma revisão bibliográfica a partir do refinamento dos dados resultantes de buscas em bases de dados acadêmicas. Inicialmente, identificamos 205 produções, das quais triamos 35, e reduzindo para 18 após seleção final: 3 artigos, 11 dissertações e 4 teses. Ainda que as produções valorizem o engajamento e a participação dos estudantes, nenhuma produção fez alusão à criação de material didático por parte dos alunos, muito embora houvéssemos identificado a participação deles em outras produções de materiais e/ou protótipos. Este achado da revisão indica a necessidade de fomentar a criação e construção colaborativa de materiais didáticos de ensino de ciências pelos alunos.
Accounting of Tumbilotohe: An Islamic Ethnomethodology Study
Authors: Thalib Mohamad Anwar
Published: July 2024

This study aims to construct accounting practices in the implementation of tumbilotohe culture. This study uses a spiritual paradigm with an Islamic ethnomethodology approach. There are five data analysis stages: charity, knowledge, faith, revelation information, and courtesy. There were four informants in this study. The four informants were selected using a purposive sampling technique. The results of the study found that the capital for the implementation of tumbilotohe comes from natural resources that can be obtained and used free of charge by residents, donations by residents obtained through granting requests for financial assistance in the form of proposals and initiatives from residents. The practice of capital accounting is conditional on the value of sustenance from the Creator and help each other. These values are contained in the lumadu value "dilla o'onto, bo wolu-woluwo" which means invisible but there. This phrase teaches in life not only to chase what is seen but also to look for something that is not visible but exists. The next value is huyula. The results of this study contribute to the concept of accounting practice in the implementation of the tumbilotohe culture, which not only consists of materials but also requirements with local cultural values and religiosity.
Marginalije kodeksa Liber privilegiorum episcopatus Zagrabiensis :
Authors: Tabak Demo Maja
Published: July 2024

U radu je donesena analiza marginalija kartulara Zagrebačke biskupije – Liber privilegiorum episcopatus Zagrabiensis. Pisan polovicom 14. st. goticom i latinskim jezikom, ovaj kodeks broji oko 700 marginalija, koje su u radu podijeljene u dvije velike skupine: primarne (bilješke pisara, suvremene izradi kodeksa) i sekundarne (bilješke upisivane u vremenima poslije njegova nastanka). Marginalije su pisane latinskim pismom i jezikom; one pak koje se sastoje isključivo od navođenja godine bilježene su arapskim brojkama. Premda malobrojne, primarne bilješke mogu doprinijeti historiografskoj interpretaciji nastanka kartulara, govoreći i o pisarskom uzusu i naobrazbi njegova sastavljača. Sekundarne marginalije, upisivane u kodeks od 15. do 20. st., djelo su većega broja autora. Donoseći najrazličitije sadržaje, one govore o dugotrajnoj upotrebi ovoga kartulara, pružajući uvid u historijat njegova istraživanja. U radu je priložen grafički prikaz klasifikacije svih marginalnih bilješki kodeksa kao i tablica marginalija.
Podvornici i pedeli
Kraljevskoga sveučilišta Franje Josipa I. u Zagrebu 1874. – 1918.
Authors: Petrić Tatijana , Mandić Hrvoje
Published: July 2024

Autori u radu, pozivajući se na izvorno gradivo Sveučilišta u Zagrebu i mjerodavnu literaturu, govore o ulozi podvornika i pedela na Kraljevskom sveučilištu u Zagrebu. Podvornici su kao sveučilišni administrativni službenici bili nezaobilazni za održavanje sveučilišne zgrade, a pedel je bio zadužen za poslove u pisarnici i razne sveučilišne ceremonije poput inauguracije rektora, doktorskih promocija i raznih državnih procesija poput tijelovske, kad je stupao u svečanom odijelu. Uvjet za stjecanje radnoga mjesta sveučilišnoga podvornika i pedela bila je dugogodišnja vojnička služba s činom dočasnika Kraljevskoga ugarsko-hrvatskog domobranstva. U radu je analizirana uloga i djelovanje pedelske odnosno podvorničke službe na Kraljevskom sveučilištu Franje Josipa I. u Zagrebu od 1874. do 1918. godine.
Filial Quarter
Authors: Nekić Antun
Published: July 2024

The paper explores the phenomenon of the filial quarter, a specific form of female inheritance practiced among the nobility of the Kingdom of Hungary-Croatia, by focusing on medieval Slavonia as a case study. Starting from some general observations on the filial quarter, the paper subsequently delves into a more systematic analysis of the Slavonian material. It elucidates the mechanism through which the filial quarter spread to Slavonia in the 13th century, how it became an institutionalized custom in the 14th century and examines the different practices of the filial quarter being given either in land or as monetary payment.
332-OR: Multiomic Profiling of Extended Honeymoon Unveils New Therapeutic Targets
Authors: LORETELLI CRISTIAN , GOUDA ABDELRAHMAN ABDELSALAM AHMED , BEN NASR MOUFIDA , USUELLI VERA , ASSI EMMA , ZOCCHI MONICA , PETRAZZUOLO ADRIANA , PETITTI AGNESE , CANNALIRE GIUSEPPE , D'ADDIO FRANCESCA , MAMELI CHIARA , FIORINA PAOLO
Published: July 2024

Introduction & Objective: Approximately 50% of patients with new-onset Type 1 Diabetes (T1D) experience a temporary recovery in pancreatic β-cell function, termed the "honeymoon" (HM) phase, lasting approximately 7-9 months on average, and only rarely extending to years. This phase provides a crucial window for interventions to preserve insulin secretion, yet the factors contributing to its occurrence remain unclear. This study presents the first comprehensive multi-omic profiling of children with new-onset T1D in an extended honeymoon phase (ExMoon), revealing potential molecular targets for preserving β-cell mass and function.

Methods: Patients in ExMoon were defined by insulin dose-adjusted HbA1c (IDAA1c) below 9 and C peptide >300 pmol/l, sustained for at least 9 months. We conducted analyses of PBMC immunophenotype, immunoreactivity to islet antigens, serum secretomics, proteomics/metabolomics/lipidomics, and PBMC transcriptomics using flow cytometry, ELISpot, immunomagnetic separation, mass spectrometry, and RNA sequencing, respectively. Profiles of ExMoon patients were compared to age- and gender-matched patients with T1D not in the HM phase (n=10 per group), with 10 matched nondiabetic patients included as additional controls.

Results: Differential serum levels of immune factors (IP-10, IL-2, FGF2), proteins (TGM2, SIR4), metabolites (kynurenine), and lipids (myristic acid and monoarachidonic acid triglyceride 18:0_38:6) were observed in ExMoon compared to the T1D group. PBMCs obtained from patients of the two groups exhibited distinct expression patterns of ERAP2, TSKS mRNAs, and of miR-339-3p, miR-8087-3p miRNAs. No differences were found in the proportion of immune cell subpopulations and islet autoreactivity between the ExMoon and T1D patient cohorts.

Conclusion: Our unbiased multiomic approach identified several immune and non-immune factors as potential molecular candidates for targeted therapies aimed at preserving β-cell mass and function.

Disclosure

C. Loretelli: None. A. Gouda Abdelrahman Abdelsalam: None. M. Ben Nasr: Research Support; Altheia Sciences. V. Usuelli: None. E. Assi: None. M. Zocchi: None. A. Petrazzuolo: None. A. Petitti: None. G. Cannalire: None. F. D'Addio: None. C. Mameli: None. P. Fiorina: None.

Funding

Fondazione "Romeo ed Enrica Invernizzi"
Spatial-temporal characteristics analysis of laser-induced shockwave pressure by reverse optimization with multi-island genetic algorithm
Authors: Tang Yuyuan , Nie Xiangfan , Wu Haonian , Xu Ming , Yan Li
Published: July 2024

Laser-induced shock wave (LSW) represents a significant phenomenon arising from the interaction between laser radiation and matter. In this study, we establish a finite element and optimization model constrained by a physical framework. Utilizing multichannel photon Doppler velocimeter experimental data as the target for matching, we directly acquire the spatiotemporal pressure characteristics of LSW through the multi-island genetic algorithm. The optimized outcomes show deviations from experimental results within 10%. Research reveals that the spatial uniformity of pressure deteriorates with increasing power density, accompanied by a gradual reduction in the proportion of peak pressure. Temporally, aside from the pressure caused by plasma, there are some small pressure peaks. When the laser's full width half maximum reaching 100 or 200 ns, the pressure decays prematurely. The duration of pressure does not extend to two to three times the duration of the laser pulse.
Effectiveness of Providing Brain Gym on Gross Motor Development in Preschool Children
Authors: Adzani Nursalimah Agistina , Awanis Almas , Ariyanti Lilik
Published: July 2024

Background: The golden period is the early life of a child where at the age of 0-5 years there is a very rapid brain development that affects motor development. The importance of motor development stimulation can improve and optimize growth and development, one of the stimulations that can be given is brain gym: The golden period is the early life of a child where at the age of 0-5 years there is a very rapid brain development that affects motor development. The importance of stimulating motor development can improve and optimize growth and development, one of the stimulations that can be given is brain gym.
Research Objective: To analyze the effectiveness of brain gym on gross motor development of preschool children.
Research Methods: This research design is a pretest-posttest group design with a control group. The sample was preschool children aged 4-6 years totaling 34 people consisting of intervention group (15 people) and control group (19 people). The gross motor measurement instrument used the Test of Gross Motor Development-2 (TGMD-2) technique. Brain gym was given 2 times per week for 4 weeks.
Results: The mean TGMD-2 score of the intervention group increased after being given brain gym by 1.17 points. The mean TGMD-2 score of the control group also increased by 0.16 points. The Man Whitney analysis results showed a p-value of 0.00 (value <0.05).
Conclusion: Brain gym is effective in improving the gross motor development of preschool children.
Determinants of Lack of Physical Activity in Students in Yogyakarta
Authors: Octania Salsabila Dita , Indriani Indriani , Ningrum Tyas Sari Ratna
Published: July 2024

Background: Lack of physical activity can increase the risk of health problems such as non-communicable diseases (NCDs); hypertension, Diabetes Mellitus (DM), Stroke, and several types of cancer and has benefits in preventing obesity, improving fitness and mental health. Various constraining factors affecting participation in physical activity such as lack of time, lack of facilities, lack of interest and energy have led to a significant decline in physical activity among university students. The purpose of this study was to identify physical activity and its constraints on university students. The research method used a cross-sectional approach with a cluster sampling technique. The sample in this study was 120 respondents and data analysis using Spearman's Rank correlation analysis test. The research instrument used questionnaires, namely the Global Physical Activity Questionnaire (GPAQ) and the Barriers to Being Active Quiz (BBAQ). The results showed that physical activity in students was in the low category of as many as 35 respondents (29.2%) with an average MET ± SD of 244.80 ± 209.609 per minute per week and the Spearman's Rank analysis test showed a p-value = 0.017 (<0.005) which means there is a significant relationship between obstacles and physical activity in students. Conclusion: Physical activity in students is still low and not by WHO recommendation standards so university efforts are needed to become a place for the development of health literacy as well as socialization and improvement of healthy behaviour of the academic community to become an active and healthy campus.
Tuturan Makian dalam Film Serial Omar: Analisis Sosiolinguistik
Authors: Fathurrohim Ilham Hanif , Nur Tajudin , Nugraha Tubagus Chaeru
Published: July 2024

This research focuses on the analysis of swear words in the Omar Film Series, which is then linked to the social and cultural context of Arab society at that time. The Omar Series is a film that tells the story of the life of Umar Bin Khattab, the second caliph of Islam, from his youth until his death. This film, which consists of 30 episodes, is widely watched by students in Indonesia, both to study the history of the development of Islam and to learn Arabic. The research method used in this research is descriptive qualitative. To limit the research, researchers used Wijana and Rohmadi's theory which classifies swear words based on lingual units and their references, as well as theories regarding the function of swearing according to Andersson and Trudgill. The results show that the lingual units most often used in swear words in the film are in the form of clauses. Apart from that, the most common swearing references found in this film are curses, following the ancient Arabic culture of cursing. In addition, the most frequently found function is the abusive function, namely using swearing with the aim of insulting, degrading, or even cursing.
Antibacterial Activity Test of Gel Toothpaste from Cinnamon Leaf Essential Oil ( Cinnamomum burmanni Blume.) Against Staphylococcus aureus Bacteria
Authors: Putri Chintya Dwiyunia , Elisma Elisma , Maharini Indri
Published: July 2024

Cinnamon leaf essential oil can inhibit the growth of Staphylococcus aureus bacteria because it contains cinnamaldehyde and eugenol compounds, which function as antibacterials. Staphylococcus aureus is a bacteria involved in various infections in the mouth and human body. This research aims to formulate cinnamon leaf essential oil into a gel toothpaste preparation by differentiating the concentration of cinnamon leaf essential oil as an active ingredient and testing its antibacterial activity against Staphylococcus aureus bacteria. The concentration of active ingredients in formula I is 0.5%, in formula II, 1%, and in formula III, 1.5%. Evaluation of the physical properties of gel toothpaste preparations includes organoleptic, homogeneity, spreadability, pH, viscosity, foam ability, stickiness, and antibacterial activity test against S. aureus using the well diffusion method. The results of the organoleptic and homogeneity evaluations were analyzed descriptively. In contrast, the spreadability, pH, viscosity, foam height, adhesion, stability, and antibacterial activity tests were analyzedstatistically using One-way ANOVA. Organoleptic test results showed yellowish white (FI), light yellow (FII), and yellow (FIII); all three formulas had a characteristic smell of essential oils and were semisolidand homogeneous. The spreadability test results ranged from 5-5.90 cm, pH value from 5.05-5.47, viscosity value from 31,980-43,900 Cp, foam ability from 9-14 mm and adhesion value from 05.84-08.83 seconds. The antibacterial activity test results for formulas I and II formed an inhibition zone in the strong category, while formula III formed an inhibition zone in the powerful category.
Identification of Potentially Inappropriate Medication in Geriatric Patients at Wangaya Hospital, Denpasar City with Beers Criteria and Stopp Criteria in 2023
Authors: Putri Made Shinta Sanma , Prasetya Anak Agung Ngurah Putra Riana , Kurnianta Putu Dian Marani
Published: July 2024

Geriatric (elderly) patients generally require a number of drugs (polypharmacy) to cure health-related conditions that tend to occur Potentially Inappropriate Medication (PIM). Identification of PIM is very important to prevent Drug Related Problems (DRP).  The purpose of the study was to identify the incidence of PIM using the Beers Criteria and STOPP Criteria and analyze the relationship between PIM risk factors and the incidence of PIM in geriatric patients at Wangaya Hospital, Denpasar City. This type of research is retrospective observational in a cross-sectional manner using simple random sampling techniques on all geriatric patients for the period 2023. Samples that met the inclusion criteria, namely geriatric patients aged ≥65 years in outpatient and inpatient facilities with geriatric patients who died and who were referred to other hospitals, were excluded from this study. Of the 354 samples, the prevalence of PIM in outpatient care was (4.23%) with the most common drugs being spironolactone (55.84%), Sulfonylureas (19.48%), and NSAIDs (6.49%) with Beers criteria. In hospitalization, (0.84%) with NSAIDs (25%), corticosteroids (25%), clopidogrel (25%), and antipsychotics (25%) with STOPP criteria. Based on the evaluation results, there was a very weak correlation between the number of drugs (p=0.000; r=0.199) and there was no relationship between the number of diagnoses (p=0.674) prescribed and the incidence of PIM. Based on this, it can be concluded that the greater the number of diseases and the number of drugs can increase the risk of PIM.
Pengembangan Cultural Tourism pada Kampung Wisata Melalui Branding dan Pemasaran digital
Authors: Kussudyarsana K , Widi Utami Dyah , Halim
Published: July 2024

Pengabdian Masyarakat ini bertujuan untuk mengembangkan wisata budaya (cultural tourism) di Kampung Kemlayan, Kecamatan Serengan, Kotamadya Surakarta. Kemlayan selama ini dikenal sebagai tempat banyak maestro budaya lahir, namun mengalami degradasi sebagai dampak dari aktivitas ekonomi yang terjadi di daerah tersebut. Kegiatan pengabdian masyarakat diharapkan dapat mengembalikan lagi citra Kemlayan sebagai Kampung Budaya.   Terdapat empat strategi utama utama yang diterapkan dalam PKM pengembangan wisata budaya Kampung Kemlayan. Pertama, ditetapkanlah jalur wisata Kampung Kemlayan dengan empat tema utama: sejarah, budaya, maestro, dan kuliner. Kedua, dilakukan kegiatan branding melalui pembuatan logo, maskot, dan simbol. Aspek ketiga mencakup pembuatan strategi pemasaran digital wisata Kampung Kemlayan melalui platform sosial media seperti TikTok, YouTube, dan Instagram. Keempat, dilakukan pelatihan pengelolaan media sosial kepada masyarakat setempat. Hasil dari kegiatan ini telah di rasakan manfaatnya oleh masyarakat sekitar, khususnya mitra PKM yaitu LPMK Kemlayan yang tercermin pada kepuasan mereka atas kegiatan pengabdian masyarakat ini yang angkanya di atas 80%.
Currículo
Authors: Pottmeier Sandra , Caetano Marta Helena Cúrio de , Ferri Cássia , Fischer Adriana
Published: July 2024

Este artigo busca compreender o que enunciam estudantes do primeiro ano do Novo Ensino Médio de uma escola pública catarinense sobre práticas de leitura e escrita na esfera escolar. A metodologia é a de abordagem qualitativa etnográfica, a qual analisa discursos de estudantes, na relação com o que se propõe no currículo da rede pública catarinense, com apoio de uma perspectiva dialógica da linguagem e de estudos do letramento. Os resultados apontaram que o currículo contempla a formação humana e integral. Contudo, é nos dizeres dos estudantes que as práticas de letramentos, em suportes digitais, ainda têm sido pouco desenvolvidas na escola, em parte, devido à dificuldade de acesso à internet e à pouca utilização de ferramentas digitais. Considera-se que, apesar de alguns avanços, há barreiras estruturais e de formação docente quanto ao uso de tecnologias digitais no Novo Ensino Médio.
Role of Tetracyclines in Joint Arthroplasties
Authors: Passadi Kalliroi-Antonia , Fryda Zoi , Lepetsos Panagiotis , Zafeiris Christos P.
Published: July 2024

Tetracyclines have various connections to total joint arthroplasties, including their potential use in perioperative infection prophylaxis, treatment of periprosthetic infections and mitigation of complications such as osteolysis and aseptic loosening. The present study is a narrative review focusing on the potential association of tetracyclines with joint arthroplasties. Tetracyclines have several potential uses in the context of arthroplasties, although they are not commonly used as prophylactic antibiotics during surgery due to concerns about their efficacy against the typical pathogens associated with surgical site infections. However, in the case of prosthetic joint infections, tetracyclines may be considered as part of the antibiotic regimen. After successful treatment of a prosthetic joint infection, some patients may require long-term antibiotic suppression therapy to prevent the recurrence of infection. Tetracyclines, such as doxycycline, may be one option for long-term oral antibiotic therapy in these cases. Minocycline-induced black bone disease and skin pigmentation are adverse events that should be taken into consideration, in terms of joint arthroplasties. The use of doxycycline in the prevention of osteolysis and aseptic loosening is an area of interest and ongoing research in orthopedic surgery, particularly in the context of total joint arthroplasties. Finally, tetracycline labeling in bones can provide valuable insights into implant incorporation and aseptic loosening of prosthetic joints.
Unele considerații privind urmarea infracțiunii de abuz în serviciu
Authors: Resmeriță Clement Mihai
Published: July 2024

Practica judiciară recentă relevă necesitatea de a combate anumite conduite ale funcționarilor publici cu anumite mijloace de drept penal. Este abuzul in serviciu în serviciu un bun instrument în această privință? Lucrarea încearcă să ofere câteva răspunsuri legate de modul de reglementare al infracțiunii de abuz in serviciu prin raportare la practica judiciară recentă și elemente de drept comparat. Lucrarea vine în contextul unor dezbateri pe marginea modificării conținutului constitutiv al infracțiunii și oferă unele propuneri având la bază argumente legate de practica judiciară română și străină precum și tendințe internaționale în acest domeniu.
Intervensi Head Up 15-30 Derajat Terhadap Perfusi Serebral Pasien Traumatic Brain Injury: Studi Kasus
Authors: Saputra La Ode Agustino , Hafid Muh. Anwar , Jamaluddin Ahmad
Published: July 2024

Latar Belakang: cedera kepala atau traumatic brain injury (TBI) merupakan suatu gangguan yang bersifat traumatik pada fungsi otak baik disertai dengan pendarahan maupun tanpa perdarahan dalam jaringan otak. Kejadian trauma kepala diperkirakan mencapai 500.000 kasus tiap tahunnya dengan angka kematian lebih dari 10% pasien meninggal sebelum tiba di rumah sakit dan lebih dari 100.000 pasien mengalami berbagai kecacatan. Fenomena yang ditemukan selama di lapangan bahwa pasien cedera kepala akibat kecelakaan lalu lintas yang dirawat di ruangan ICU Rumah Sakit Labuang Baji Makassar, mengalami gangguan perfusi serebral, penurunan kesadaran dan beberapa pasien mengalami nyeri kepala sebagai dampak dari ketidakefektifan perfusi serebral. Penanganan utama pada pasien cedera kepala adalah peningkatan status O2 dan memposisikan pasien dengan head up 15-300. Metode: metode penelitian yang digunakan ialah metode studi kasus dengan melakukan proses keperawatan dimulai dari pengkajian sampai evaluasi pada kasus traumatic brain injury di ruangan Intensive Care Unit (ICU) rumah sakit Labuang Baji Makassar. Hasil:   Diagnosis keperawatan yang ditemukan ialah risiko perfusi jaringan serebral tidak efektif, gangguan mobilitas fisik, risiko defisit nutrisi, dan risiko infeksi. Pembahasan: intervensi head up 15-300 dapat melancarkan perfusi serebral dan menurunkan tekanan intrakranial melalui beberapa mekanisme, yakni menurunkan tekanan darah, perubahan ventilasi, meningkatkan aliran vena melalui vena jugularis yang tak  berkatup, sehingga menurunkan volume darah vena sentral yang menurunkan tekanan intrakranial. Perpindahan CSS dari kompartemen intrakranial ke rongga subarachnoid spinal1 dapat menurunkan tekanan intrakranial dan memperbaiki perfusi serebral. Kesimpulan: intervensi head up 15-300 efektif untuk mengatasi masalah risiko perfusi serebral tidak efektif.
Pengaruh Kombinasi Foothbath Therapy Dan Aromaterapi Lavender Terhadap Penurunan Skala Nyeri Ibu Post SC Di RSIA Jimmy Medika Borneo Samarinda
Authors: Handayani Yuni Puspo , Hartati Dwi , Sumiati Sumiati , Hadiningsihi Eka Frenty
Published: July 2024

Latar Belakang: Pasien post Sectio Caesarea seringkali mengalami nyeri hebat, meskipun tersedia obat-obat analgesik yang efektif, sekitar 60% pasien post SC masih mengalami nyeri dalam 12-48 jam pos partum. Rasa nyeri yang dirsakan ibu post SC berdampak sangat komplek bagi perawatan ibu postpartum, yaitu terhambatnya mobilisasi dini dan terhambatnya laktasi, Penanganan non farmakologi salah satunya adalah Kombinasi foothbath therapy dan aromaterapi lavender yang efektif menurunkan nyeri pada ibu post section caesarea. Tujuan: mengetahui pengaruh kombinasi foothbath therapy dan aromaterapi lavender terhadap penurunan skala nyeri pada ibu post section caesarae di RSIA Jimmy Medika Borneo Samarinda. Metode: Jenis penelitian kuantitataif dengan metode penelitian pre-eksperiment dengan pendekatan one grup pretest–posttest desain, sampel sebesar 30 ibu post section caesarea menggunakan teknik Consecutive sampling. Instrumen menggunakan lembar observasi numeric rating scale (NRS) dan SOP. Hasil: Diperoleh dari 30 responden sebagian besar sebelum di lakukan intervensi mengalami nyeri sedang sebanyak 21 orang (70%) dan sesudah intervensi 23 orang (76,7%) mengalami nyeri ringan. Berdasarkan hasil uji statistic Wilcocoxon Signed Rank Test , menunjukan bahwa pengaruh antara dua variable adalah sebesar -5.013 dengan p value 0,00 (α≤0,05). Simpulan: Terdapat pengaruh kombinasi foothbath therapy dan aromaterapi lavender terhadap penurunan skala nyeri pada ibu post section caesarae di RSIA Jimmy Medika Borneo Samarinda. Saran: Therapy non farmakologi kombinasi foothbath therapy dan aromaterapi lavender dapat diterapakan di RS untuk mengurangi rasa nyeri pada ibu post SC.
The Overview of Nutritional Status, Physical Activity, Menstrual Patterns, and Washing Behavior on teenagers
Authors: Bahar Hartati , Nur Hasanah Indah , Lestari Hariati
Published: July 2024

Anemia is a common health problem in Indonesia. One-third of teenagers, or three to four out of ten teenagers, suffer from anemia. The aim of this research was to determine the nutritional health picture of adolescent girls at SMPN 12 Kendari based on their level of exercise, menstrual cycle, and habit of washing their hands with soap (CTPS). The population in this study was 42 grade 9 students. The sampling technique was simple random sampling with a research sample of 30 young women. Questionnaires are used to collect data to measure respondents' attitudes and behavior. The results showed that of the 30 respondents whose data were taken, there were 15 respondents who had a thin nutritional status (50%), there were 20 respondents who did light exercise (66.7%), there were 24 respondents with normal menstrual patterns (80%), and There were 21 respondents who had hand washing behavior that met the requirements (65.6%).  It is hoped that young women will pay more attention to their daily consumption patterns so that they comply with balanced nutrition to improve their nutritional status.
Analisis Masalah Kesehatan di Kota Bandar Lampung, Malaria Tetap Menjadi Masalah Utama
Authors: Nasyaroeka Ayu Eka Buana Dewi , Sulistyawati Sulistyawati , Kurniawan Medi
Published: July 2024

The Indonesian government wants to eradicate malaria in 2030. This suggests that throughout the previous three years, no native malaria cases had been discovered across the nation. It follows that every region needs to keep an eye on the malaria condition in its own territory. One of the areas with endemic malaria is Lampung Province. The purpose of this study is to analyze health issues and determine whether malaria is still a concern in Bandar Lampung City.  USG was used to calculate the problem priority. Results, With an 80, malaria was found to be the main health problem. In conclusion, Bandar Lampung City's greatest challenge is still malaria.
 
Keywords :  Malaria Control, USG, Lampung, vector control,  public health problem
Optimasi Ukuran Kulit Mangga pada Ekoenzim dengan Sumber Karbon Molase
Authors: Shalihah Nuha Fathinah , Firlianti Sekar Putri , Hardhaneszha Azkaifa Syawqie , Djuarsa Peristiwati
Published: July 2024

Latar Belakang: Ekoenzim merupakan salah satu hasil proses fermentasi yang memiliki banyak manfaat dengan memanfaat sampah organik seperti kulit mangga. Tujuan:  Penelitian ini bertujuan untuk mengetahui perbedaan karakteristik ekoenzim berbahan limbah kulit mangga dengan perbedaan ukuran kulit mangga yang akan difermentasi. Metode: Penelitian ini dilakukan tiga tahapan; fermentasi pembuatan ekoenzim, uji organoleptik, serta uji kuantitatif. Variasi ukuran kulit mangga yang digunakan mulai dari ukuran kecil (1x2 cm), ukuran sedang (2x4 cm), dan ukuran besar (4x8 cm). Uji organoleptik dilakukan kepada 10 panelis dengan parameter yang sudah ditentukan, uji ini mencakup uji aroma dan uji warna ekoenzim. Uji kuantitatif dilakukan dengan mengukur pH ekoenzim menggunakan pH meter. Seluruh pengujian dilakukan pada 3 perlakuan eco-enzyme yang berbeda dengan 3 kali pengulangan, eco-enzyme tersebut di panen pada hari ke-35. Hasil: Pada uji organoleptik didapatkan bahwa ekoenzim dengan ukuran kulit mangga terkecil (1x2 cm) memiliki nilai yang lebih tinggi dari segi aroma juga warna dibandingkan dengan ekoenzim dengan ukuran yang lebih besar. Sedangkan pada uji kuantitatif didapatkan pH ekoenzim dengan ukuran kulit 1x2 cm memiliki pH paling asam. Dalam pembuatan ekoenzim kali ini juga didapatkan jamur pitera yang bermanfaat bagi kulit. Kesimpulan: Ukuran kulit mangga yang digunakan pada mini riset ini didapatkan ekoenzim paling baik yaitu ukuran terkecil (1x2 cm) menghasilkan nilai pH paling asam, nilai aroma terbaik yaitu 2,6 dan nilai warna terbaik yaitu 2,7.
The Effectiveness of Audio-Visual Media on Changes In Knowledge, Attitudes, and Behavior of "Resti" Mothers to Use Contraception in Kramatwatu District, Serang Regency, Banten Province
Authors: Ade Handriati  , Irfa Kartini  , Rahayu
Published: July 2024

Pendahuluan: Jumlah kematian Ibu di Banten tertinggi yaitu di Kabupaten Serang yaitu 66 kasus kematian Ibu.(Rachmawati 2021). Penyebab tertinggi kematian Ibu adalah hipertensi kehamilan. Hipertensi dalam kehamilan tejadi pada Ibu dengan usia resiko tinggi, sehingga perlu ditunda atau disudahi kehamilannya pada usia resiko tinggi dengan menggunakan kontrasepsi. Tujuan penelitian ini yaitu mengetahui efektivitas media audio visual terhadap perubahan pengetahuan, sikap dan perilaku Ibu untuk menggunakan kontrasepsi. Metode: Metode penelitian ini adalah Quasi Eksperimen dengan rancangan the one group pretest posttest design.(Swarjana 2015). Responden dalam penelitian ini yaitu wanita usia subur dengan resiko tinggi. Hasil: Hasil Uji Wilcoxon diketahui bahwa adanya perbedaan skor pengetahuan dan sikap Ibu sebelum dan sesudah diberikan intervensi media audio visual dengan nilai signifikansi 0,00 (p value < 0,05). Adanya perubahan perilaku Ibu sebelum dan sesudah diberikan intervensi media audio visual dengan nilai signifikansi 0,046 (p value < 0,05). Kesimpulan: Terdapat pengaruh pemberian pendidikan kesehatan dengan media audiovisual terhadap pengetahuan, sikap dan perilaku ibu dalam menggunakan kontrasepsi.