bluuebunny/crossref_metadata_2025 huggingface dataset:
The Answer Job Did Not Give: Dostoevsky's "Brat'ia Karamazovy" and Camus's "La Peste"
Authors: Lešić-Thomas Andrea
Published: February 2022

Abstract: This article explores the similarities and differences between the characters of Dostoevsky's "Brat'ia Karamazovy" and Camus's "La Peste," focusing on these novels' interpretation of the Book of Job and the Gospels. Camus's interpretation of Dostoevsky's key characters illuminates some contradictions in Dostoevsky's Christian vision. Camus recasts Dostoevsky's faithless rebels as inspirational heroes rebelling against the absurdity of existence and the Christian God, and he recasts some of Dostoevsky's Christian heroes as atheist or agnostic rebels. In this polemical reshuffling of values and personalities, Camus's own morality of responsible humanist hedonism becomes clearer, while Dostoevsky's troubled Christian vision becomes more problematic.
Photon transport enhancement through a coupled-cavity QED system with dynamic modulation
Authors: Kato Shinya , Aoki Takao
Published: February 2022

We investigate photonic transport through fiber optical cavities under tunable fast modulation, which is induced by modulating atom-cavity coupling in a cavity quantum electrodynamics (CQED) system. The modulation bandwidth exceeds the timescales of all other system processes, such as cavity decay and atom-cavity coupling, and allows control of the dynamics of photonic transport through the cavity array. The transmission as a function of the modulation frequency clearly shows enhancement peaks in single cavity and two coupled-cavity cases. In particular, in the coupled-cavity case, the position of the enhancement peak is shifted due to the delocalized cavity field in the coupled system.
Diode-pumped Dy:KPb2Cl5 laser in the middle-infrared spectral region
Authors: Schlosser Peter , Isaenko Ludmila , Tarasova Aleksandra , Savitski Vasili
Published: February 2022

A Dy:KPb2Cl5 (KPC) laser oscillating at approximately 4.4 µm under diode laser pumping at 1.7 µm is demonstrated for the first time. A maximum output pulse energy of 1.1 mJ was achieved at 10 mJ of absorbed pump energy. Tunable laser oscillation in the 4.2–4.5 µm spectral range was recorded with this crystal. Limitations of Dy:KPC for laser oscillation due to its challenging thermo-optical properties are discussed. This crystal is a further addition to the range of low-phonon-energy materials doped with Dy ions that can be applied for laser oscillation in the mid-infrared spectral range under direct diode laser pumping.
Evaluating spatially adaptive guidelines for the treatment of gonorrhea to reduce the incidence of gonococcal infection and increase the effective lifespan of antibiotics
Authors: Yaesoubi Reza , Cohen Ted , Hsu Katherine , Gift Thomas L. , St. Cyr Sancta B. , Salomon Joshua A. , Grad Yonatan H.
Published: February 2022

In the absence of point-of-care gonorrhea diagnostics that report antibiotic susceptibility, gonorrhea treatment is empiric and determined by standardized guidelines. These guidelines are informed by estimates of resistance prevalence from national surveillance systems. We examined whether guidelines informed by local, rather than national, surveillance data could reduce the incidence of gonorrhea and increase the effective lifespan of antibiotics used in treatment guidelines. We used a transmission dynamic model of gonorrhea among men who have sex with men (MSM) in 16 U.S. metropolitan areas to determine whether spatially adaptive treatment guidelines based on local estimates of resistance prevalence can extend the effective lifespan of hypothetical antibiotics. The rate of gonorrhea cases in these metropolitan areas was 5,548 cases per 100,000 MSM in 2017. Under the current strategy of updating the treatment guideline when the prevalence of resistance exceeds 5%, we showed that spatially adaptive guidelines could reduce the annual rate of gonorrhea cases by 200 cases (95% uncertainty interval: 169, 232) per 100,000 MSM population while extending the use of a first-line antibiotic by 0.75 (0.55, 0.95) years. One potential strategy to reduce the incidence of gonorrhea while extending the effective lifespan of antibiotics is to inform treatment guidelines based on local, rather than national, resistance prevalence.
DBT affects sleep in both circadian and non-circadian neurons
Authors: Wang Jialin , Fan Jin-Yuan , Zhao Zhangwu , Dissel Stephane , Price Jeffrey
Published: February 2022

Sleep is a very important behavior observed in almost all animals. Importantly, sleep is subject to both circadian and homeostatic regulation. The circadian rhythm determines the daily alternation of the sleep-wake cycle, while homeostasis mediates the rise and dissipation of sleep pressure during the wake and sleep period. As an important kinase, dbt plays a central role in both circadian rhythms and development. We investigated the sleep patterns of several ethyl methanesulfonate-induced dbt mutants and discuss the possible reasons why different sleep phenotypes were shown in these mutants. In order to reduce DBT in all neurons in which it is expressed, CRISPR-Cas9 was used to produce flies that expressed GAL4 in frame with the dbt gene at its endogenous locus, and knock-down of DBT with this construct produced elevated sleep during the day and reduced sleep at night. Loss of sleep at night is mediated by dbt loss during the sleep/wake cycle in the adult, while the increased sleep during the day is produced by reductions in dbt during development and not by reductions in the adult. Additionally, using targeted RNA interference, we uncovered the contribution of dbt on sleep in different subsets of neurons in which dbt is normally expressed. Reduction of dbt in circadian neurons produced less sleep at night, while lower expression of dbt in noncircadian neurons produced increased sleep during the day. Importantly, independently of the types of neurons where dbt affects sleep, we demonstrate that the PER protein is involved in DBT mediated sleep regulation.
Benefit-risk analysis of maintaining essential Reproductive, Maternal, Newborn, and Child Health (RMNCH) services against risk of COVID-19 infection
Authors: Weissman Eva , Buchner Denise , Hemachandra Nilmini , Siddeeg Khalid , Samim Soroush Mohammad , Rahmanzai Ahmed Javed , Chikvaidze Paata , Yassen Zaid Muayad , Hasan Hanan , Berraho Mohamed , Dghoughi Nouzha , Hafid Hachri , Zaidi Raza Mahmood , Zulfiqar Wahaj , Awes Sayema , Aabroo Atiya , Uzma Qudsia , Fiidow Mohamed Abubakar Hagi Mohamed , Afrah Abdulkadir Wehliye , Ali Abdullahi Abdulle , Awadalla Abdulazim Ali , EL Hassan Muntasir Mohammed Osman , Elkheir Esmehan Babeker , Diaz Theresa
Published: February 2022

With the COVID-19 pandemic spreading across the world, its disruptive effect on the provision and utilization of non- COVID related health services have become well-documented. As countries developed mitigation strategies to help continue the delivery of essential health services through the pandemic, they needed to carefully weigh the benefits and risks of pursuing these strategies. In an attempt to assist countries in their mitigation efforts, a Benefit-Risk model was designed to provide guidance on how to compare the health benefits of sustained essential reproductive, maternal, newborn and child (RMNCH) services against the risk of SARS-CoV-2 infections incurred by the countries’ populations when accessing these services. This article describes how two existing models were combined to create this model, the field-testing process carried out from November 2020 through March 2021 in six countries and the findings. The overall Benefit-Risk Ratio in the 6 countries analyzed was found to be between 13.7 and 79.2, which means that for every 13.7 to 79.2 lives gained due to increased RMNCH service coverage, there was one loss of a life related to COVID-19. In all cases and for all services, the benefit of maintaining essential health services far exceeded the risks associated with additional COVID-19 infections and deaths. This modelling process illustrated how essential health services can continue to operate during a pandemic and how mitigation measures can reduce COVID-19 infections and restore or increase coverage of essential health services. Overall, this Benefit-Risk analysis underscored the importance and value of maintaining coverage of essential health services even during public health emergencies, including the recent COVID-19 pandemic
Assessment of heavy metal pollution in surface sediments of the Chishui River Basin, China
Authors: Li Fanxi , Yu Xia , Lv Jiemei , Wu Qixin , An Yanling
Published: February 2022

Accumulated heavy metals in surface sediments are released into the aquatic environment, causing secondary contamination of the hydrosphere, and increasing the risks to human health. To evaluate the pollution characteristics of heavy metals in the sediments of the Chishui River Basin, in the present study, the concentrations of five heavy metals in surface sediments of the Chishui River Basin in China were investigated using the geo-accumulation index, pollution load index, and potential ecological risk indexes. These indexes evaluated the degree of contamination and the influence of human activities on heavy metal levels in the basin. Cu, Zn, Cd, Hg, and As were found at concentrations of 5.12–120.40, 36.01–219.31, 0.03–1.28, 0.01–1.18, and 1.56–11.59 mg kg–1, respectively, with mean values of 37.43, 91.92, 0.25, 0.07, and 5.16 mg kg–1, respectively, in the order Zn > Cu > As > Cd > Hg. The contamination indices revealed Hg as the principal pollutant based on the spatial distribution, while Pearson’s correlation coefficients suggested that Cu, Zn, and As originated from a similar source. Hg had a different source from the other metals, whereas Cd originated from a different source compared with that of Zn, As, and Hg. This paper showed a Hg and Cd contamination in the Chishui River Basin.
The impact of the COVID-19 pandemic on scientific research in the life sciences
Authors: Riccaboni Massimo , Verginer Luca
Published: February 2022

The COVID-19 outbreak has posed an unprecedented challenge to humanity and science. On the one side, public and private incentives have been put in place to promptly allocate resources toward research areas strictly related to the COVID-19 emergency. However, research in many fields not directly related to the pandemic has been displaced. In this paper, we assess the impact of COVID-19 on world scientific production in the life sciences and find indications that the usage of medical subject headings (MeSH) has changed following the outbreak. We estimate through a difference-in-differences approach the impact of the start of the COVID-19 pandemic on scientific production using the PubMed database (3.6 Million research papers). We find that COVID-19-related MeSH terms have experienced a 6.5 fold increase in output on average, while publications on unrelated MeSH terms dropped by 10 to 12%. The publication weighted impact has an even more pronounced negative effect (-16% to -19%). Moreover, COVID-19 has displaced clinical trial publications (-24%) and diverted grants from research areas not closely related to COVID-19. Note that since COVID-19 publications may have been fast-tracked, the sudden surge in COVID-19 publications might be driven by editorial policy.
Misinformation, believability, and vaccine acceptance over 40 countries: Takeaways from the initial phase of the COVID-19 infodemic
Authors: Singh Karandeep , Lima Gabriel , Cha Meeyoung , Cha Chiyoung , Kulshrestha Juhi , Ahn Yong-Yeol , Varol Onur
Published: February 2022

The COVID-19 pandemic has been damaging to the lives of people all around the world. Accompanied by the pandemic is aninfodemic, an abundant and uncontrolled spread of potentially harmful misinformation. The infodemic may severely change the pandemic’s course by interfering with public health interventions such as wearing masks, social distancing, and vaccination. In particular, the impact of the infodemic on vaccination is critical because it holds the key to reverting to pre-pandemic normalcy. This paper presents findings from a global survey on the extent of worldwide exposure to the COVID-19 infodemic, assesses different populations’ susceptibility to false claims, and analyzes its association with vaccine acceptance. Based on responses gathered from over 18,400 individuals from 40 countries, we find a strong association between perceived believability of COVID-19 misinformation and vaccination hesitancy. Our study shows that only half of the online users exposed to rumors might have seen corresponding fact-checked information. Moreover, depending on the country, between 6% and 37% of individuals considered these rumors believable. A key finding of this research is that poorer regions were more susceptible to encountering and believing COVID-19 misinformation; countries with lower gross domestic product (GDP) per capita showed a substantially higher prevalence of misinformation. We discuss implications of our findings to public campaigns that proactively spread accurate information to countries that are more susceptible to the infodemic. We also defend that fact-checking platforms should prioritize claims that not only have wide exposure but are also perceived to be believable. Our findings give insights into how to successfully handle risk communication during the initial phase of a future pandemic.
Predicted 3D model of the M protein of Porcine Epidemic Diarrhea Virus and analysis of its immunogenic potential
Authors: Rodríguez-Enríquez Alan , Herrera-Camacho Irma , Millán-Pérez-Peña Lourdes , Reyes-Leyva Julio , Santos-López Gerardo , Rivera-Benítez José Francisco , Rosas-Murrieta Nora Hilda
Published: February 2022

The membrane protein M of the Porcine Epidemic Diarrhea Virus (PEDV) is the most abundant component of the viral envelope. The M protein plays a central role in the morphogenesis and assembly of the virus through protein interactions of the M-M, M-Spike (S) and M-nucleocapsid (N) type. The M protein is known to induce protective antibodies in pigs and to participate in the antagonistic response of the cellular antiviral system coordinated by the type I and type III interferon pathways. The 3D structure of the PEDV M protein is still unknown. The present work exposes a predicted 3D model of the M protein generated using the Robetta protocol. The M protein model is organized into a transmembrane and a globular region. The obtained 3D model of the PEDV M protein was compared with 3D models of the SARS-CoV-2 M protein created using neural networks and with initial machine learning-based models created using trRosetta. The 3D model of the present study predicted four linear B-cell epitopes (RSVNASSGTG and KHGDYSAVSNPSALT peptides are noteworthy), six discontinuous B-cell epitopes, forty weak binding and fourteen strong binding T-cell epitopes in the CV777 M protein. A high degree of conservation of the epitopes predicted in the PEDV M protein was observed among different PEDV strains isolated in different countries. The data suggest that the M protein could be a potential candidate for the development of new treatments or strategies that activate protective cellular mechanisms against viral diseases.
A scoping review of the contralateral effects of unilateral peripheral stimulation on neuromuscular function
Authors: Zhou Shi , Zhang Shuang-Shuang , Crowley-McHattan Zachary J.
Published: February 2022

It is known that resistance exercise using one limb can affect motor function of both the exercised limb and the unexercised contralateral limb, a phenomenon termed cross-education. It has been suggested that cross-education has clinical implications, e.g. in rehabilitation for orthopaedic conditions or post-stroke paresis. Much of the research on the contralateral effect of unilateral intervention on motor output is based on voluntary exercise. This scoping review aimed to map the characteristics of current literature on the cross-education caused by three most frequently utilised peripheral neuromuscular stimulation modalities in this context: electrical stimulation, mechanical vibration and percutaneous needling, that may direct future research and translate to clinical practice. A systematic search of relevant databases (Ebsco, ProQuest, PubMed, Scopus, Web of Science) through to the end of 2020 was conducted following the PRISMA Extension for Scoping Review. Empirical studies on human participants that applied a unilateral peripheral neuromuscular stimulation and assessed neuromuscular function of the stimulated and/or the unstimulated side were selected. By reading the full text, the demographic characteristics, context, design, methods and major findings of the studies were synthesised. The results found that 83 studies were eligible for the review, with the majority (53) utilised electrical stimulation whilst those applied vibration (18) or needling (12) were emerging. Although the contralateral effects appeared to be robust, only 31 studies claimed to be in the context of cross-education, and 25 investigated on clinical patients. The underlying mechanism for the contralateral effects induced by unilateral peripheral stimulation remains unclear. The findings suggest a need to enhance the awareness of cross-education caused by peripheral stimulation, to help improve the translation of theoretical concepts to clinical practice, and aid in developing well-designed clinical trials to determine the efficacy of cross-education therapies.
Optimizing environmental safety and cell-killing potential of oncolytic Newcastle Disease virus with modifications of the V, F and HN genes
Authors: de Graaf J. Fréderique , van Nieuwkoop Stefan , Bestebroer Theo , Groeneveld Daphne , van Eijck Casper H. J. , Fouchier Ron A. M. , van den Hoogen Bernadette G.
Published: February 2022

Newcastle Disease Virus (NDV) is an avian RNA virus, which was shown to be effective and safe for use in oncolytic viral therapy for several tumour malignancies. The presence of a multi basic cleavage site (MBCS) in the fusion protein improved its oncolytic efficacy in vitro and in vivo. However, NDV with a MBCS can be virulent in poultry. We aimed to develop an NDV with a MBCS but with reduced virulence for poultry while remaining effective in killing human tumour cells. To this end, the open reading frame of the V protein, an avian specific type I interferon antagonist, was disrupted by introducing multiple mutations. NDV with a mutated V gene was attenuated in avian cells and chicken and duck eggs. Although this virus still killed tumour cells, the efficacy was reduced compared to the virulent NDV. Introduction of various mutations in the fusion (F) and hemagglutinin-neuraminidase (HN) genes slightly improved this efficacy. Taken together, these data demonstrated that NDV with a MBCS but with abrogation of the V protein ORF and mutations in the F and HN genes can be safe for evaluation in oncolytic viral therapy.
Social media usage to share information in communication journals: An analysis of social media activity and article citations
Authors: Özkent Yasemin
Published: February 2022

Social media has surrounded every area of life, and social media platforms have become indispensable for today’s communication. Many journals use social media actively to promote and disseminate new articles. Its use to share the articles contributes many benefits, such as reaching more people and spreading information faster. However, there is no consensus in the studies that to evaluate between tweeted and non-tweeted papers regarding their citation numbers. Therefore, it was aimed to show the effect of social media on the citations of articles in the top ten communication-based journals. For this purpose, this work evaluated original articles published in the top 10 communication journals in 2018. The top 10 communication-based journals were chosen based on SCImago Journal & Country Rank (cited in 2019). Afterward, it was recorded the traditional citation numbers (Google Scholar and Thompson-Reuters Web of Science) and social media exposure of the articles in January 2021 (nearly three years after the articles’ publication date). It was assumed that this period would allow the impact of the published articles (the citations and Twitter mentions) to be fully observed. Based on this assessment, a positive correlation between exposure to social media and article citations was observed in this study.
Keap1 recognizes EIAV early accessory protein Rev to promote antiviral defense
Authors: Wang Yan , Ma Guanqin , Wang Xue-Feng , Na Lei , Guo Xing , Zhang Jiaqi , Liu Cong , Du Cheng , Qi Ting , Lin Yuezhi , Wang Xiaojun
Published: February 2022

The Nrf2/Keap1 axis plays a complex role in viral susceptibility, virus-associated inflammation and immune regulation in host cells. However, whether or how the Nrf2/Keap1 axis is involved in the interactions between equine lentiviruses and their hosts remains unclear. Here, we demonstrate that the Nrf2/Keap1 axis was activated during EIAV infection. Mechanistically, EIAV-Rev competitively binds to Keap1 and releases Nrf2 from Keap1-mediated repression, leading to the accumulation of Nrf2 in the nucleus and promoting Nrf2 responsive genes transcription. Subsequently, we demonstrated that the Nrf2/Keap1 axis represses EIAV replication via two independent molecular mechanisms: directly increasing antioxidant enzymes to promote effective cellular resistance against EIAV infection, and repression of Rev-mediated RNA transport through direct interaction between Keap1 and Rev. Together, these data suggest that activation of the Nrf2/Keap1 axis mediates a passive defensive response to combat EIAV infection. The Nrf2/Keap1 axis could be a potential target for developing strategies for combating EIAV infection.
Craftsmanship: Interview with Roger W. Smith, horologist
Authors: Borstrock Shaun
Published: February 2022

In contemporary terms, luxury has come to mean many things to many people. It is no longer commonly defined within the confines of true meaning and understanding of skill, craftsmanship, heritage and provenance. Materials do not necessarily have to be the best; the maker no longer needs to have an understanding of the full process of manufacture; they can be skilled in one operation thus removing them from the ‘heart’ of the product. In this interview with master horologist Roger W. Smith, we explore the true meaning of craftsmanship from a mastercraftsman, one of the few people in the world who can make a watch from start to finish. For a master horologist like Roger W. Smith, the fundamental definition of luxury is unchanging.
Trends in Global Infrastructure Investment and Financial Consequences
Authors: Gundes Selin
Published: February 2022

Governments all around the world are faced with economic and social problems borne from the need for modern and reliable infrastructure. Rapid urbanization, increasing population size and economic growth are the main causes of increasing infrastructure investment needs in the world. While the need is growing, government budgets are increasingly squeezed by demands for healthcare improvements, defence, education and many others. The problems in the provision of finance for these investments are aggravated with the new Covid crisis, as the funds reserved for infrastructure investments are now likely to be allocated to urgent needs such as healthcare and unemployment benefits. In such a volatile environment, identifying future investment needs and discussing how these needs will be met is important and timely more than ever. This paper, introduces the global infrastructure investment trends in the future and discusses the use of public and private finance for infrastructure spending. In this concept, the following questions are explored, (1) What is the volume and trend of global infrastructure investment needs? (2) How do infrastructure investment needs differ among regions? (3) How will this infrastructure investment needs be financed?, and (4) What may be some of the future issues to be solved? To find out future infrastructure investment needs and trends, reports outlining the future prospects of the infrastructure sector are examined and trends are revealed. Then, a review of financing mechanisms is introduced in the light of the main procurement systems used by governments for realizing infrastructure projects. In this concept, design-bid-build, design-build and project finance models are explored in terms of their organizational and financial structure. Future issues to be solved are mainly derived from a cross examination of concerns raised in published infrastructure investment case studies and of future trends. Results reveal that the need for investment in infrastructure is growing steadily. As a response to this growth, the use of private finance is increasingly being encouraged by governments all over the world and a variety of international organizations. However, it appears that long-standing private finance issues predominantly observed in demand-based projects will continue to be discussed over the coming years by policymakers, scholars and communities. Indeed, many governments and organizations are already speeding up research efforts into ensuring the resilience of public private partnerships (PPP) in infrastructure projects. The insights from this research are expected to revive interest and research efforts into the potential future challenges for infrastructure financing and options available for governments.
Technological Interventions for Augmenting Income of Rural Households in India
Authors: Srinivas K. J. , Giridhar Prof. B Sai
Published: February 2022

One of the central issues which policy makers constantly try to address in developing countries is to explore ways to augment income of rural households. India being an agrarian economy, most of its population depend on farming as main source of income. But, large section of the farming population is distressed and look for alternative income augmenting avenues. A possible solution to enhance income of farmers is adopting technology in farming practices. With this background, the paper based on secondary data sources explores how technological interventions can help farmers to augment their income
AS DISPUTAS E A LÓGICA FRAGMENTÁRIA: NOVAS RELAÇÕES ENTRE ESPAÇOS PÚBLICOS E PRIVADOS EM CHAPECÓ - SC
Authors: Bender Pablo Martin , Góes Eda Maria
Published: February 2022

Neste artigo são discutidas as novas relações entre espaços públicos e espaços privados estabelecidas a partir da revisão do Plano Diretor de Chapecó, em 2006, e seus impactos. Se verificaram uma série de ações e leis tendentes a afastar os jovens, principalmente os das periferias, do centro de Chapecó, além de normas e programas da prefeitura que promovem e regulamentam a expansão dos interesses comerciais e empresariais sobre a gestão do espaço público. Mas também se observou os limites desses programas e as novas práticas espaciais dos jovens no centro, evidenciando mudanças nas relações entre público e privado. Se conclui que tendências como a privatização estão presentes, dentre outras que configuram o processo de fragmentação socioespacial, mas há disputa.
O PAPEL DOS AGENTES DO TURISMO A PARTIR DO MAPA DO TURISMO BRASILEIRO EM MARABÁ-PA
Authors: Serra Hugo Rogério Hage , Paz Izabela Rodrigues
Published: February 2022

Este trabalho tem como objetivo principal identificar e analisar a atuação dos agentes produtores do turismo em Marabá, bem como esses agentes reproduzem de forma política e espacial os critérios do Mapa do Turismo Brasileiro (MTB). O papel que Marabá, enquanto cidade média, exerce na região Sul e Sudeste do Pará norteou esta pesquisa, bem como o interesse pela análise regional de como as políticas públicas de turismo operam – ou não – em uma região. Parte-se de uma metodologia que considera as contradições histórico-regionais de Marabá, assim como a força econômico-regional que implica nas decisões para o turismo na cidade. Para tanto, a revisão breve de literatura sobre políticas públicas e das cidades médias foram necessárias. O uso de observação direta de reuniões dos agentes do turismo e as entrevistas compõem os procedimentos metodológicos. Afirma-se que o fato de Marabá ser a principal cidade econômica das regiões Sul e Sudeste do Pará influencia consideravelmente na organização e nas decisões políticas sobre o turismo para além de seus limites administrativos por meio da atuação dos agentes do turismo, considerados agentes de decisão na tomada dos critérios do MTB.
MODELAGEM APLICADA NA ESTIMATIVA DE VAZÃO DE UMA BACIA HIDROGRÁFICA NO SUDOESTE DE GOIÁS, CERRADO BRASILEIRO
Authors: Alves Wellmo dos Santos , Martins Alécio Perini , Ferreira Raina Santos
Published: February 2022

É fundamental uma gestão dos recursos hídricos que integre os diferentes usuários e que garanta, com vistas ao desenvolvimento sustentável, a disponibilidade hídrica para toda a sociedade. Assim, torna-se importante a geração de dados para subsidiar o planejamento e a gestão de bacias hidrográficas (BH) de forma condizente com o desenvolvimento ecologicamente equilibrado. Considerando o exposto, objetivou-se estimar a vazão hídrica em sete pontos na BH do Rio Verdinho, no Sudoeste de Goiás, Cerrado Brasileiro. Foi usado o modelo Soil and Water Assessment Tool (SWAT), sendo a modelagem realizada no ArcSWAT e calibração no SWAT-Calibration and Uncertainty Proceduresfoi (SWAT-CUP), com uso do algoritmo Sequential Uncertainty Fitting para análise de sensibilidade. Os resultados pós processo de calibração (NS=0,53, R²=0,83 e PBIAS=-22,5) evidenciam que o modelo SWAT simulou de forma satisfatória a vazão, sendo observado que o SWAT-CUP teve dificuldade de ajustar as variáveis terrestres evapotranspiração e escoamento de base. Esse estudo servirá de base para outras pesquisas em ambientes de Cerrado, principalmente na região Sudoeste de Goiás, onde não são observados estudos com o referido modelo. Os resultados também subsidiarão ações e políticas públicas efetivas e eficientes na gestão hídrica local e regional.
Editorial
Authors: Seneda Marcos César
Published: February 2022

Temos o prazer de apresentar para o leitor o número 61 do volume 31 da Revista Educação e Filosofia. Tendo completado três décadas de publicações ininterruptas, a Revista surge em 2017 com uma importante migração formal, que marcará todos os seus volumes a partir desse momento. Conforme anunciado no editorial do último número publicado em 2016, comemorativo dos trinta anos de existência, a Revista passa agora a ser quadrimestral, publicando oficialmente três números por ano. A publicação de três números anuais já ocorria desde 2011, mas o terceiro número sempre era designado como número especial. [...]Com o intuito de persistir nessa tarefa, o número sessenta e um, do trigésimo primeiro volume da Revista Educação e Filosofia, publica, para a apreciação dos seus leitores, vinte e dois artigos e uma resenha. Neste número da Revista ora publicado, o leitor poderá encontrar trabalhos em Filosofia e Educação que versam sobre diferentes áreas de pesquisa nestas duas especialidades. [...]É este o número que ora oferecemos para o leitor, com o nosso desejo de divulgar da melhor forma possível, agora em formato quadrimestral, o conhecimento produzido e confiado a Revista Educação e Filosofia.
Hacia una Administración Pública interoperable: interpretación y análisis jurídico del silencio como consecuencia de no intercambiar información requerida entre organismos públicos
Authors: Stringhini Antonella
Published: February 2022

El objetivo del artículo es realizar una interpretación y análisis jurídico del silencio como consecuencia de no intercambiar información requerida entre organismos públicos, regulada en el artículo 4 del Decreto Nacional N°733/2018 de la República Argentina. En concreto, objetiva dilucidar el carácter que se le debe otorgar a la información que no es intercambiada por el organismo público requerido.
Impact of Ethical Leadership on Team Performance: the Mediating Role of Resolution Efficacy and Individual Performance
Authors: Al -Musawi Abbas N. , Al –Mahdawi Batool M. , Al-Tameemi Rusol N.
Published: February 2022

The purpose of this study is to investigate the impact of ethical leadership on team performance with mediating role of resolution efficacy and individual performance. Design/Methodology/Approach: This study is conducted in telecom sector of Qatar; self-administrative questionnaire is used for data collection. The collected data for the study was tested with the help of two statistical software SPSS and AMOS. Different tests were run in order to test the research hypothesis and confirm it objectives, i.e., descriptive, correlation KMO and factor loading, CFA and SEM. Findings: The findings of the study indicated that ethical leadership has positive and significant impact on team performance in Qatar telecom sector. Results also prove that resolution efficacy and individual performance significantly mediates between ethical leadership and team performance. Implications: This study will be significant both theoretically and practically. In theory, evidence in the literature on the study topic will increase. In the practical field, this study will help in implementing the teamwork in telecom sector of Qatar to improve it outcomes. Policymakers can also benefit from the study as it will help those updating policies on ethical leadership for positive outcomes. Originality/Value: The study presents a research model that is investigated for the first time in the telecom sector of Qatar.
Strategic Planning Using Engaged Scholarship: Building A Reentry Organization
Authors: Watson Jerry
Published: February 2022

Given the incredible growth in incarceration numbers and resultant increases in returning prisoners, reentry programs play a critical role in the lives of justice involved individuals and their families, and communities.  The aim of this engaged scholarship effort was to work in partnership with a community-based reentry organization to conduct strategic planning.  Among the unique organizational assets identified were mental health services, social support groups, clinical professional development, and social entrepreneurship including housing and innovative technology development initiatives. Building on Indomitable Families Affected by Incarceration’s history, strengths, and opportunities, the results yielded a set of action steps to guide the organization’s future.
A comparison of in-service teachers’ conceptions of barriers to mobile technology-integrated instruction and technology-integrated instruction
Authors: Chen Chih-Hung , Siu-Yung Jong Morris , Tsai Chin-Chung
Published: February 2022

Researchers have identified three orders of barriers to probe teachers’ conceptions of technology-integrated instruction, namely extrinsic obstacles, intrinsic obstacles and the lack of design thinking. However, few studies have investigated barriers to teachers’ mobile technology-integrated instruction and compared them with the barriers to their technology-integrated instruction. This study recruited 20 in-service teachers with experience in adopting mobile learning (in practice) to compare their conceptions of the two kinds of barriers. Firstly, we utilised the phenomenographic method and subsequently transformed qualitative interview data into quantitative data. The research results found an additional crucial barrier, namely classroom management. Thus, this study revealed four classifications of barriers to (mobile) technology-integrated instruction. Moreover, teachers with less experience in adopting mobile learning confronted more obstructions to mobile technology-integrated instruction than to technology-integrated instruction at the first-order level (i.e., extrinsic obstacles). On the contrary, teachers with more experience in adopting mobile learning encountered more barriers related to design thinking upon the educational integration of mobile technology over conventional technology. This study provides the field with new insights into understanding teachers’ conceptions of barriers to the adoption of emerging technology-integrated instruction and sheds light for researchers and policymakers who are working on teacher professional development.
Implications for practice or policy:

This research reveals a framework of the four orders of barriers for providing an understanding of teachers’ barriers to advanced technology-integrated instruction as the technology grows.
More courses involving design thinking for mobile learning should be provided as part of teacher training.
Future research should carefully explore the effective solutions for eliminating the barriers to mobile technology-integrated instruction.
The absolute thermoelectric power of Nb–Mo alloys
Authors: Brodowsky Horst , Chen Qiyuan , Xiao Zhongliang , Yin Zhoulan
Published: February 2022

After Onsager the thermopower of a material is related to the ratio either of two transport coefficients or of the gradients of the electrochemical potential of the electrons and the temperature. In metals the potential is a unique function of the temperature and this ratio can be replaced by the differential quotient, a function obtainable from the density of states of the metal as illustrated on a thermopower isotherm of Nb–Mo alloys.
God Who Comes to Mind: Emmanuel Levinas as Inspiration and Challenge for Theological Thinking
Authors: Sirovátka Jakub
Published: February 2022

From the beginning, Levinas’ thought was received not only by philosophers but also by theologians. But his thought is very radical and represents both a challenge and an inspiration for theology. The article aims to see where the challenge and inspiration might lie. Levinas’s basic question is how finite thought can think an infinite and transcendent God. Levinas develops the phenomenology of the Idea of the Infinite and interprets Descartes’ idea of God as a practical desire. For Levinas, the relation to God is intrinsically linked to the relation to the Other. It is an attempt to characterize an autonomous ethical subjectivity whose autonomy, however, does not begin with the subject but in the Other, in whom the presence of God is always already manifest. This description of the subject corresponds to the human being as understood in Christian theology.
Fausta Gantús, Alicia Salmerón y Florencia Gutiérrez, La toma de las calles. Movilización social frente a la campaña presidencial, ciudad de México, 1892
Authors: Rodríguez Pairol Ibisamy
Published: February 2022

Reseña a: Fausta Gantús, Alicia Salmerón y Florencia Gutiérrez, La toma de las calles. Movilización social frente a la campaña presidencial, ciudad de México, 1892.
The Effects of High-Repetition Strength Training on Performance in Competitive Endurance Athletes: A Systematic Review and Meta-Analysis
Authors: Nugent Frank J. , Flanagan Eamonn P. , Darragh Ian , Daly Laura , Warrington Giles D.
Published: February 2022

Nugent, FJ, Flanagan, EP, Darragh, I, Daly, L, and Warrington, GD. The effects of high-repetition strength training on performance in competitive endurance athletes: A systematic review and meta-analysis. J Strength Cond Res 37(6): 1315–1326, 2023—The aim of this systematic review and meta-analysis was to evaluate the effects of high-repetition strength training (HRST) on performance in competitive endurance athletes. The methodology followed the Preferred Reporting Items for Systematic Review and Meta-Analysis protocol. A search of databases was performed until December 2020. Inclusion criteria were (a) competitive endurance athletes, (b) ≥4 weeks HRST intervention, (c) control or comparison group, (d) outcome measures of performance (either physiological or time trial performance), and (e) all experimental designs. Quality assessment was performed using the Physiotherapy Evidence Database (PEDro) scale. Of the 615 studies retrieved, 11 studies were included (216 subjects) and 9 studies provided sufficient data for the meta-analysis (137 subjects). The PEDro scale score had a mean of 5 of 10 points (range: 3–6). There was no significant difference between the HRST and control groups (g = 0.35; 95% confidence interval [CI] = −0.38 to 1.07; p = 0.35) or HRST and low-repetition strength training (LRST) groups (g = 0.24; 95% CI = −0.24 to 0.72; p = 0.33). The findings of this review and meta-analysis indicate that HRST does not result in improved performance over a 4- to 12-week period, and the results seem to be similar to LRST. The majority of studies involved recreational endurance athletes and had a mean duration of 8 weeks, which is a limitation of the findings. Future intervention studies should be > 12 weeks in duration and involve well-trained endurance athletes (maximal oxygen uptake [V̇o
2max] of >65 ml·kg−1·min−2).
From “Isn’t It Raw?” to Everyday Food
Authors: Fukutomi Satomi
Published: February 2022

With a focus on the role of social media, this article examines the ways in which Japanese food is authenticated and popularized as everyday food in Perth, Australia. Preceding the 2000s, Japanese food was scarcely available in Perth; the city with a small Japanese population was relatively far from Japan. In the 2010s, Japanese food, once mainly known as raw fish (sushi, sashimi) and high-end food, has transformed into everyday food, available at eateries, grocery stores, and farmers markets. I argue that the ever-growing popularity of social media allows consumers to exchange their experiences and knowledge of Japanese food and to create their versions of authenticity of the food. Authenticity is subjective and depends on people’s perceptions, and people share these perceptions on social media. Based on my fieldwork at Japanese eateries and one of the local farmers markets, as well as analysis of social media, this article illustrates consumers’ stories, authenticity, and their impact on Perth’s foodscape.
Narrative Strategies of Criminal Legitimacy
Authors: Mekenkamp Marloes
Published: February 2022

This article looks at how criminal agents aim to gain legitimacy within the context of the War on Drugs in Mexico. More precisely, it explores the narrative of legitimization presented in Me dicen “el más loco”, an autobiography of Nazario Moreno González, the leader of the criminal organization La Familia Michoacana. A cultural-studies approach is used to argue that the book combines a Christian version of the social-bandit myth with the narrative strategies of the picaresque novel to legitimize the activities of the group. This article aims to contribute to the larger debate on the powerful imaginary dimension of organized crime in Mexico.
Cryopreservation as Biotechnological Application of Dendritic Cells in Clinical Practice
Authors:   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Goltsev Anatoliy ,   Interdepartmental Scientific Center of the National Academy of Sciences of Ukraine, Academy of Medical Sciences of Ukraine and Ministry of Health of Ukraine, Kharkiv, Yampolska Katerina ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv,   Interdepartmental Scientific Center of the National Academy of Sciences of Ukraine, Academy of Medical Sciences of Ukraine and Ministry of Health of Ukraine, Kharkiv, Kisielova Hanna ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Оstankov Maksym ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Dubrava Tatiana ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Babenko Natalya ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Gaevska Yuliya ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine, Bondarovych Mykola ,   Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
Published: February 2022

An important component of the pathogenesis of autoimmune diseases is the immune system deregulation as an impaired tolerance to its own antigens by reducing the content of T-regulatory cells. Their formation is closely related to the function of dendritic cells (DCs), so in autoimmune diseases the use of DCs with tolerogenic potential is promising for the restoration of antigen-specific tolerance. Recently, the issue of establishing the banks of tolerogenic DCs for clinical use, which involves their cryopreservation, has been actively discussed. To date, there is no common protocol for DCs freezing, which would take into account the different sources of their obtaining, the initial structural and functional state before freezing, composition of cryopreservation media and other factors. The review summarizes experimental data on cryopreservation of peripheral blood and bone marrow mononuclear cells or monocytes. The potential for their further ex vivo differentiation into DCs to ensure the stability of immature phenotype and tolerogenic function has been studied.
Blood Characteristics in Dogs During Treatment of Babesiosis Using Transfusion of Cryopreserved Erythrocytes
Authors:   State Biotechnological University, Institute of Veterinary Medicine and Animal Husbandry, Denysova Оlha , Zhegunov Gennadiy ,   State Biotechnological University, Institute of Veterinary Medicine and Animal Husbandry, Yakimenko Tatyana ,   State Biotechnological University, Institute of Veterinary Medicine and Animal Husbandry, Hladka Nataliia ,   State Biotechnological University, Institute of Veterinary Medicine and Animal Husbandry, Prichodchenko Vita ,   State Biotechnological University, Institute of Veterinary Medicine and Animal Husbandry, Bobrutska Olha ,   State Biotechnological University, Institute of Veterinary Medicine and Animal Husbandry
Published: February 2022

Babesiosis is one of the most common protozoan diseases in dogs, which in the absence of the necessary veterinary care often leads to the animal death. The changes of hematological parameters in dogs during complex treatment of babesiosis and transfusion of cryopreserved erythrocytes were evaluated in the research. Erythrocytes were frozen using 20% DMSO by immersion into liquid nitrogen. Transfusion of cryopreserved erythrocytes together with antiparasitic chemotherapy has been shown to promote rapid recovery of hematological parameters of animal blood (hemoglobin, hematocrit and erythrocyte counts), as well as improves their well-being, promotes faster recovery. Cryopreserved with DMSO erythrocytes can be recommended for long-term storage of blood at cryobanks.
Фотолюмінесцентні властивості шаруватих твердих розчинів Pb1-xCdxI2
Authors: Гнатенко Ю.П. , Фур’єр М.С. , Буківський П.М. , Скубенко П.А. , Пирятинський Ю.П. , Гамерник Р.В.
Published: February 2022

Проведено дослідження спектрів фотолюмінесценції, в тому числі із розділенням в часі, і фотодифузійного струму кристалів PbI2 та твердих розчинів Pb1-xCdxI2. Встановлено, що дані кристали мають монополярну (діркову) провідність. Показанаможливість утворення в твердих розчинах кластерів PbI2 різних розмірів. Встановлено, що величина розщеплення між Γ3–- та Γ1–-екситонними станами в таких кластерах становить 30 та 36 меВ для x = 0,50 та x = 0,70, відповідно. Виявлено, що для x ≥ 0,50 має місце автолокалізація екситонів в кластерах PbI2.