bluuebunny/crossref_metadata_2025 huggingface dataset:
Kriminologin som inomverksforskning - exemplet brå
Authors: Tham Henrik
Published: March 2020

See abstract in article.
Domme om særlig økonomisk kriminalitet
Authors: Pedersen Jan
Published: March 2020

See abstract in article.
Polisen och brottsuppklaringen
Authors: Knutsson Johannes
Published: March 2020

See abstract in article.
Når skaden skal gjøres god igjen
Authors: Prieur Annick
Published: March 2020

See abstract in article.
Svensk kronik
Authors: Örn Claes , Björkman Ulla , Bishop Norman , Heckscher Sten
Published: March 2020

Svensk kronik
Rättssäkerheten och de nya brottsundersökningsmetoderna
Authors: Holmer Hans
Published: March 2020

See abstract in article.
Strafferetligt ansvar uden skyld
Authors: Kruse Sysette Vinding
Published: March 2020

See abstract in article.
Norsk kronik
Authors: Coward Kirsti
Published: March 2020

Norsk kronik
Brannstiftere
Authors: Grünefeld Berthold , Noreik Kjell
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Vängby Staffan , Wolf Preben , Bramstång Gunnar , Krogh Tyge , Greve Vagn , Olafsdottir Hildigunnur
Published: March 2020

Book reviews
En studie i verdens mest tyvagtige folkefærd
Authors: Balvig Flemming
Published: March 2020

See abstract in article.
Anbringelsesdømte; varighed og lovovertrædelse
Authors: Rehof Lars Adam , Trier Klaus
Published: March 2020

See abstract in article.
En afdelingsleders arbejde i den frie kriminalforsorg
Authors: Skovgaard Lotte
Published: March 2020

See abstract in article.
Kriminalomsorg - kontrollomsorg
Authors: Harstad Harald
Published: March 2020

See abstract in article.
Kronik fra Europarådet 1982-84
Authors: . NTfK
Published: March 2020

Kronik fra Europarådet 1982-84
Boganmeldelser
Authors: Malmsten Krister , Jensen Sv. Gram
Published: March 2020

Book reviews
Närmare den stora nya lagen - en granskning av det finska strafflagsprojektets första delbetänkande
Authors: Träskman P. O.
Published: March 2020

See abstract in article.
Børn i fængsel sammen med voksne
Authors: Nielsen Beth Grothe
Published: March 2020

See abstract in article.
Brott, straff och moral
Authors: Ekelöf Per Ole
Published: March 2020

See abstract in article.
De nordiska kriminalisterna och kriminalpolitiken
Authors: Lång K. J.
Published: March 2020

See abstract in article.
Frihetsstraff mot unge lägoverträdare i Norden
Authors: Sveri Knut
Published: March 2020

See abstract in article.
Provokation
Authors: Hirsch Andrew Von , Jareborg Nils
Published: March 2020

See abstract in article.
Skräckbrottslingar och brottsskräck
Authors: Träskman P. O.
Published: March 2020

See abstract in article.
Kampen om den tvungne voldgift 1927-1929. Et bidrag til den sivile ulydighetens kriminologi
Authors: Johansen Per Ole
Published: March 2020

See abstract in article.
Straffeproces og den europæiske menneskerettighedskonvention
Authors: Rehof Lars Adam
Published: March 2020

See abstract in article.
Tugt og dadel
Authors: Frosell Bertil A.
Published: March 2020

See abstract in article.
Straff och proportionalitet
Authors: Hirsch Andrew Von , Jareborg Nils
Published: March 2020

See abstract in article.
Slutreplik
Authors: Bondeson Ulla
Published: March 2020

Slutreplik til Echhart Kühlhorn
Den paradoxala fångvården och dess dolda uppgift
Authors: Hinkkanen-Lievonen Merja-Liisa
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Gottlieb Peter , Kallehauge H. , Nielsen Gorm Toftegaard , Nielsen Beth Grothe , Garde Peter , Ebskov Eric Bo , Bødal Kåre , Heilbo J. , Greve Vagn , Rasmussen Nell , Hauge Ragnar , Anttila Inkeri , Kyvsgaard Britta , Svensson Bo , Grünewald Ann-Britt , Koch Henning
Published: March 2020

Book reviews
Strafferetlige reaktioner over for psykisk afvigende lovovertrædere, som ikke er utilregnelige
Authors: Kallehauge Holger
Published: March 2020

See abstract in article.
Voldsstraffene i historisk lys
Authors: Waaben Knud
Published: March 2020

See abstract in article.
Nordisk fengselsstatistikk
Authors: Bødal Kåre , Fridhov Inger M. , Hammerlin Yngve
Published: March 2020

See abstract in article.
Indhold
Authors: . NTfK
Published: March 2020

Indhold anno 1989
Double criminality as a requirement to jurisdiction
Authors: Wyngaert Christine Van den
Published: March 2020

See abstract in article.
The use of foreign law in domestic adjudication
Authors: Cornils Karin
Published: March 2020

See abstract in article.
The role of double criminality in international cooperation in penal matters
Authors: Plachta Michal
Published: March 2020

See abstract in article.
"Boomerangsakene" i Bergen
Authors: Bjørvik Kjell Inge
Published: March 2020

See abstract in article.
Kriminalpolitik og ideologi i det danske folketing
Authors: Lutz Gene M.
Published: March 2020

See abstract in article.
Mökligheten att handla annorlunda som en förutsättning för skyldansvar - syften och värderingar
Authors: Nuutila Ari-Matti
Published: March 2020

See abstract in article.
Norsk rettspraksis 1986-1989
Authors: Slettan Sven , Øie Toril M.
Published: March 2020

See abstract in article.
Indhold
Authors: . NTfK
Published: March 2020

Indhold anno 1990
Elektronisk overvågning i Marin Amt, Californien
Authors: Sørensen Kirsten
Published: March 2020

See abstract in article.
Talmagi eller åben diskussion
Authors: Gabrielsen Gorm
Published: March 2020

See abstract in article.
Kriminalisering av det reisende folket i Norge
Authors: Schlüter Ragnhild
Published: March 2020

See abstract in article.
Bemærkninger til advokat Erling Andresen
Authors: Stevnsborg Henrik
Published: March 2020

Kommentar til Erling Andresen.
Islamisering og dens indflydelse på kvinders retlige situation
Authors: Mehdi Rubya
Published: March 2020

See abstract in article.
Kvinners møte med politiet
Authors: Vegheim Berit
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Rynning Elisabeth , Gottlieb Peter , Ericsson Kjersti , Gregersen M. , Dünkel Frieder , Andersen Heidi Mork , Ljungstrøm Alexander Carnera , Skjørsten Kristin
Published: March 2020

Book reviews
Video-optagede politiafhøringer af børn, der er anmeldt for at have været udsat for seksuelt misbrug
Authors: Olsen Tony , Schlegel Ilse , Hermann Kai , Merlung Erik
Published: March 2020

See abstract in article.
Norsk kronik
Authors: Larsson Paul , Schea Trond Eirik , Bødal Kåre , Fridhov Inger Marie , Hammerlin Yngve
Published: March 2020

Norsk kronik
Retsstillingen for ofre i U.S.A
Authors: Frese-Madsen Malene
Published: March 2020

See abstract in article.
Finsk kronik
Authors: Träskman P. O.
Published: March 2020

Finsk kronik
Tingsrätternas straffmätningspraxis vid brott enligt BrB kap. 1 § och speciellt grov våldtäkt, 1989-92
Authors: Klette Hans
Published: March 2020

See abstract in article.
Internationaliseringen av straffrätten
Authors: Lahti Raimo
Published: March 2020

See abstract in article.
Strafbegrebet i forhold til straffens målsætning og retfærdiggørelse
Authors: Thormundsson Jonatan
Published: March 2020

See abstract in article.
Ærekrænkelser - behandles de groveste seriøst af myndighederne?
Authors: Nielsen Gorm Toftegaard
Published: March 2020

See abstract in article.
"Forebygging av kriminalitet" altfor bredt og altfor smalt
Authors: Giertsen Hedda
Published: March 2020

See abstract in article.
Om Nils Christe: Kriminalitetskrontoll som industri: mot Gulag vestlig type (Oslo: Universitetsforlaget, 1993)
Authors: Hirsch Andrew Von
Published: March 2020

Book review
Boganmeldelser
Authors: Larsson Paul , Nielsen Beth Grothe , Frimodt-Møller Niels , Bladh Christine , Tamm Ditlev , Tranøy Joar , Aromaa Kauko
Published: March 2020

Book reviews
Sprøytebruk - kriminalitet: Høna og egget
Authors: Skretting Astrid
Published: March 2020

See abstract in article.
Udviklingen i antallet af tilsynsklienter idømt psykiatriske særforanstaltninger fra 1977 til 1993
Authors: Kramp P. , Gabrielsen G.
Published: March 2020

See abstract in article.
Nödrätten i efterbelysning
Authors: Tuori Kaarlo
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Sahlin Ingrid , Kongstad Annalise , Nielsen Beth Grothe , Aromaa Kauko , Eliasson Mona , Gottlieb Peter , Østergaard-Nielsen Ulf , Storgaard Anette , Herlitz Carl Erik , Kirkegaard Henning , Garde Peter , Frese-Madsen Malene , Olaussen Leif Petter , Klette Hans , Stevnsborg Henrik , Greve Vagn
Published: March 2020

Book reviews
Boganmeldelser
Authors: Mathiesen Thomas , Larsson Paul , Nielsen Beth Grothe , Ericsson Kjersti , Anttila Inkeri , Waaben Knud , Aromaa Kauko , Järvinen Margaretha , Blume Peter , Langsted Lars Bo , Greve Vagn
Published: March 2020

Book reviews
Indhold
Authors: . NTfK
Published: March 2020

Indhold anno 1995
Empiri og ideologi i kriminologi: Den objektive og subjektive siden av kriminaliteten i Island
Authors: Gunnlaugsson Helgi
Published: March 2020

See abstract in article.
Bydelspoliti og lokalkultur
Authors: Sæter Oddrun
Published: March 2020

See abstract in article.
Grænser for vækst i verdens fangetal
Authors: Nielsen Beth Grothe
Published: March 2020

See abstract in article.
The penal system and other forms of social control in Russia: Problems, perspectives
Authors: Gilinskiy Yakov
Published: March 2020

See abstract in article.
Behandling som alternativ til frihedsstraf
Authors: Koch Ida Elisabeth
Published: March 2020

See abstract in article.
Häkten och fängelser hos Europarådets medlemsstater
Authors: Franck Hans Göran
Published: March 2020

See abstract in article.
Kriminologi - faglige krav og kriterier
Authors: Christie Nils
Published: March 2020

See abstract in article.
Utvecklingen av den tyska abortlagstiftningen i jämförelse med utvecklingen i Norden
Authors: Tallroth Paulina
Published: March 2020

See abstract in article.
Ungdomsbrottslighetens utveckling i Sverige. Minskning, avmattning eller oförminskad ökning?
Authors: Estrada Felipe
Published: March 2020

See abstract in article.
Kunsten at slå to fluer med et smæk - uden at slå ruden itu
Authors: Kyvsgaard Britta
Published: March 2020

See abstract in article.
"Corpus juris" - ett frestande eller ett främmande förslag till en enhetlig europeisk rättssfär?
Authors: Träskman Per Ole
Published: March 2020

See abstract in article.
Indhold
Authors: . NTfK
Published: March 2020

Indhold anno 1997
FN-krönika: Förenta nationerna och kriminalpolitiken
Authors: Joutsen Matti
Published: March 2020

See abstract in article.
Galskapens hus i Norge: Det første reforminitiativ
Authors: Blomberg Wenche
Published: March 2020

See abstract in article.
Påföljdsval vid rattfylleri: Effekter av 1990 års reform av trafikbrottslagen
Authors: Nordström Thor
Published: March 2020

See abstract in article.
Fler åtalade unga lagöverträdare: Allvarligare brott eller hårdare tag?
Authors: Lindström Peter
Published: March 2020

See abstract in article.
Ullersmoprosjektet: "Scared straight" i Norge 1992-1996
Authors: Storvoll Elisabet E. , Hovland Arild
Published: March 2020

See abstract in article.
Krönika från EU:S ministerråd
Authors: Nilsson Hans G.
Published: March 2020

Krönika från EU:S ministerråd
Boganmeldelser
Authors: Koch Ida , Nielsen Beth Grothe , Matikkala Jussi , Frände Dan , Garde Peter , Larsson Paul
Published: March 2020

Book reviews
Æresmedlemmets indlæg
Authors: Waaben Knud
Published: March 2020

Æresmedlemmets indlæg
Bølger i den kriminalpolitiske udvikling.
Authors: Nielsen Lars Nordskov
Published: March 2020

Foredrag ved Dansk Kriminalistforenings 100-års jubilæum, d. 26. november 1999.
Kriminalpolitik og strafferetlig lovgivning på tærsklen til et nyt årtusind.
Authors: Nielsen Beth Grothe
Published: March 2020

See abstract in article.
Arbetet inom ramen för förenta nationernas kriminalpolitiska program - en uppdatering
Authors: Joutsen Matti
Published: March 2020

See abstract in article.
Styring med straf
Authors: Waaben Knud
Published: March 2020

See abstract in article.
IKT-kriminalitet: Efterforskningsmetoder og personvern
Authors: Sunde Inger Marie
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Garde Peter , Frände Dan , Nielsen Beth Grothe , Bergquist Martin , Koch Ida , Larsson Paul , Ericsson Kjersti , Träskman Per Ole
Published: March 2020

Book reviews
På internets bakgård - svensk rasideologiska webbplatser 1996-2000
Authors: Sjöberg Anders
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Sandmo Erling , Johansen Nicolay B. , Gundhus Helene O. , Matikkala Jussi , Garde Peter , Koch Ida , Giertsen Hedda , Larsson Paul , Nielsen Beth Grothe
Published: March 2020

Book reviews
Politi- og ikke-politianmeldt voldtægt og voldtægtsforsøg i Århus Amt i perioden 1. november 1999 - 1. november 2000
Authors: Charles Annie Vesterby , Brink Ole , Banner Jytte
Published: March 2020

See abstract in article.
Straffrättens förutsättningar och begränsningar som styrmedel av miljöskadlig verksamhet
Authors: Träskman Per Ole
Published: March 2020

See abstract in article.
Politivoldsakene i Bergen - status etter 19 år med dyp uenighet
Authors: Eriksen Morten
Published: March 2020

See abstract in article.
Kronikk Norge 1999-2001
Authors: Larsson Paul , Hennum Ragnhild , Strandbakken Asbjørn
Published: March 2020

Norsk kronik
Boganmeldelser
Authors: Finstad Liv , Kyvsgaard Britta , Sahlin Ingrid , Garde Peter , Träskman Per Ole , Olsen Irene Fogh , Hammerlin Yngve , Frände Dan , Larsson Paul , Ericsson Kjersti
Published: March 2020

Book reviews
Det danske EU-formandskab på det politimæssige og strafferetlige område
Authors: Scharf Jakob
Published: March 2020

See abstract in article.
Aktuel europæisk strafferetsudvikling - strafferetligt samarbejde
Authors: Elholm Thomas
Published: March 2020

See abstract in article.
Utvecklingen av straffrättsliga påföljderna i Finland
Authors: Lappi-Seppälä Tapio
Published: March 2020

See abstract in article.
Utvecklingen av de straffrättsliga påföljderna i Sverige
Authors: Bäcklund Agneta , Lundkvist Peter
Published: March 2020

See abstract in article.
Tal av republikens president Tarja Halonen vid Nordiska Kriminalistmötet vid Helsingfors Universitet den 10.6.2004
Authors: . NTfK
Published: March 2020

Tal av republikens president Tarja Halonen vid Nordiska Kriminalistmötet vid Helsingfors Universitet den 10.6.2004
Fruktbarhet sikres ved argumentasjon, ikke med erklæringer
Authors: Olaussen Leif Petter
Published: March 2020

Kommentar til Nils Christie
"Folkeoplysning eller rettens trivalisering"? Synspunkter fremkommet på høstmøte i Den Norske Kriminalistforening
Authors: Hustad Knut-Fredrik
Published: March 2020

See abstract in article.
Uenighetens kjerne: Kriminalitetens vesen
Authors: Olaussen Leif Petter
Published: March 2020

Kommentar til Morten Eriksen
Boganmeldelser
Authors: Träskman Per Ole , Greve Vagn , Larsson Paul , Tham Henrik , Paul Rachel , Hennum Ragnhild , Jacobsson Katarina , Strandbakken Asbjørn , Kramp Peter , Ebbesson Jonas , Olaussen Leif Petter
Published: March 2020

Book reviews
Polisiär nolltolerans: Flipp eller flopp?
Authors: Lindström Peter
Published: March 2020

See abstract in article.
Ökat våld och/eller vidgade definitioner? En empirisk och teoretisk analys av den långsiktiga vålds-utvecklingen
Authors: Hofer Hanns Von
Published: March 2020

See abstract in article.
Riktlinjer för framtidens kriminalpolitik och för straffrättsliga reformer
Authors: Asks Beatrice
Published: March 2020

See abstract in article.
Kriminalitetsrejsen. Om indbrydstyves mobilitet.
Authors: Sorensen David WM
Published: March 2020

See abstract in article.
Europoakonvensjonens "immunisering" av massemediene
Authors: Aarli Ragna
Published: March 2020

See abstract in article.
Kundskabsbaseret kriminalforsorgspolitik
Authors: Kyvsgaard Britta
Published: March 2020

See abstract in article.
Påföljder för unga - ett system med två svårförenliga principer
Authors: Holmberg Stina
Published: March 2020

See abstract in article.
Är skulden evig?
Authors: Pirjatanniemi Elina
Published: March 2020

See abstract in article.
"Narkotikaen er fattig manns arbeidsgiver". Organisert kriminalitet som økonomisk aktivitet.
Authors: Larsson Paul
Published: March 2020

See abstract in article.
Kommentar till Peter Lindström
Authors: Hofer Hanns Von
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Gunnlaugsson Helgi , Garde Peter , Larsson Paul , Tham Henrik , Greve Vagn , Lied Camilla , Olausson Leif Petter , Andersson Ulrika
Published: March 2020

Book reviews
Mindeord - Knud Waaben (1921-2008)
Authors: Rentzmann William
Published: March 2020

In memory of Knud Waaben (1921-2008)
Fengslene og de psykiatriske institusjonene: Like eller forskjellige?
Authors: Dullum Jane
Published: March 2020

See abstract in article.
Om åklagare och åtalspliktens utformning i de nordiska länderna
Authors: Träskman Per Ole
Published: March 2020

See abstract in article.
Boganmeldelser
Authors: Greve Vagn , Hofer Hanns Von , Nilsson Roddy , Granér Rolf , Hammersvik Eirik , Sorensen David W. M. , Larsson Paul
Published: March 2020

Book reviews
Barn som begår lovbrudd. Norsk rett og forslag i NOU 2008: 15 Barn og straff
Authors: Fornes Ingun
Published: March 2020

See abstract in article.
Den retlige regulering af korruption i Norden
Authors: Langsted Lars Bo
Published: March 2020

See absract in article.
Kontroll av ekstraordinære etterforskningsmetoder - overvåkningssamfunnet og den nye teknikk
Authors: Dalseide Nils
Published: March 2020

See abstract in article.
Den strafferetlige behandling af bagatelagtige sager
Authors: Greve Vagn
Published: March 2020

See abstract in article.
Finns det grader i helvetet? Om köp (och försäljning) av sex
Authors: Lernestedt Claes
Published: March 2020

See abstract in article.
Forvaring - Fra særreaksjon og "straff" til lovens strengeste straff: Et skritt frem eller ett tilbake?
Authors: Johansen Berit
Published: March 2020

See abstract in article.
Preface
Authors: Baruch Adele
Published: March 2020

The Courage and Moral Choice Project (CMPC) is introduced, as is the associated research. Stories of helping under duress were brought to various settings, most extensively to high school students with integrated teacher and curriculum support. Listening to these stories appeared to elicit increased memories of helping experiences, as well as increased sharing of personal stories by participants, if engaged in a safe and/or nurturing environment. For a number of students, the stories inspired questions of moral choice and a view of oneself as part of a community “that helps.”
Chapter 1
Authors: Baruch Adele
Published: March 2020

This chapter recounts the events and early research that inspired the start of the Courage and Moral Choice Project in area schools. The project appeared to work well in a school district focused on the need to develop a climate of inclusion and empathy, as the district had recently experienced a high influx of refugees from many parts of the world into a community that had been fairly homogeneous for generations. Teachers noted an increased tendency for students to share personal stories with others after listening to stories of helping under duress. They also noted increased engagement with questions of moral choice. Both students and teachers said that they repeatedly reflected upon the question of, “What would I do if faced with similar circumstances?” Students noted that they began to identify with the stories of helpers once they engaged in service of their own.
Chapter 6
Authors: West Kim , Lane Amanda , Libby Madison
Published: March 2020

In this chapter, participants from the Courage and Moral Choice Project share personal essays about their experiences with the project. Teachers describe the ways in which they sought to connect the stories of moral courage with a deepened awareness of the needs and challenges in the school and wider community. One teacher described the stories as “reminders” that courage and goodness exist in the world, a world often filled with stories of despair. Another teacher, who was once described as an “at risk” student herself, also noted that the stories provide a perspective of hope. One student described how meaningful it was for her to hear stories about the many Danish citizens to shelter and transport their neighbors during the Nazi occupation. She notes, “I think more people need to be like that.”
Teaching Copyright Literacy in University Contexts
Authors: Högberg Charlotte
Published: March 2020

The IFLA Statement on Copyright Education and Copyright Literacy declares that libraries should work to enhance copyright literacy and that librarians should function as educators to achieve this. Libraries should offer workshops and training, especially when laws are amended. In the EU, member states need to implement the new copyright directive in their national legislation by June 2021 at the latest. This calls for additional focus on copyright education in the near future. This paper seeks to gain understanding of the prospects for teaching copyright literacy in university contexts and how the education best promote learning, by applying principles of learning processes on the teachings of copyright.

Copyright is foremost a practical matter for students and faculty, which stresses the importance of shaping the content in relation to the target group. While undergraduate students struggle with how to re-use other sources for their work, researchers are more likely to struggle with what rights they are signing away or how to re-use their own work. Tailoring instruction is crucial, but what learning processes are important specifically for the subject of copyright, and how do we best approach them to foster learning?

A set of principles is identified: activate prior knowledge, set the tone, establish ground for motivation and use case bases learning activities. These principles can enhance learning but also pose challenges, such as if prior knowledge of a differing national legislation is applied in an incorrect manner, or how to create a positive classroom climate where participants are at ease with sharing previous lack of knowledge or unlawful practice. By the use of practical scenarios make it easier to understand how copyright works. By using cases set within familiar contexts, a deeper understanding can develop and students and faculty can be empowered to solve copyright issues or know when to ask for support.
Association of sleep among 30 antidepressants: a population-wide adverse drug reaction study, 2004–2019
Authors: Eugene Andy R.
Published: March 2020

Background

Sleep is one of the most essential processes required to maintain a healthy human life, and patients experiencing psychiatric illness often experience an inability to sleep. The aim of this study is to test the hypothesis that antidepressant compounds with strong binding affinities for the serotonin 5-HT2C receptor, histamine H1 receptors, or norepinephrine transporter (NET) will be associated with the highest odds of somnolence.

Methods

Post-marketing cases of patient adverse drug reactions were obtained from the United States Food and Drug Administration Adverse Events Reporting System (FAERS) during the reporting window of January 2004 to September 2019. Disproportionality analyses of antidepressants reporting somnolence were calculated using the case/non-case method. The reporting odds-ratios (ROR) and corresponding 95% confidence interval (95% CI) were computed and all computations and graphing conducted in R.

Results

There were a total of 69,196 reported cases of somnolence out of a total of 7,366,864 cases reported from January 2004 to September 2019. Among the 30 antidepressants assessed, amoxapine (n = 16) reporting odds-ratio (ROR) = 7.1 (95% confidence interval [CI] [4.3–11.7]), atomoxetine (n = 1,079) ROR = 6.6 (95% CI [6.2–7.1]), a compound generally approved for attention deficit hyperactivity disorder (ADHD), and maprotiline (n = 18) ROR = 6.3 (95% CI, 3.9–10.1) were the top three compounds ranked with the highest reporting odds of somnolence. In contrast, vortioxetine (n = 52) ROR = 1.3 (95% CI [1.0–1.8]), milnacipran (n = 58) ROR = 2.1 (95% CI [1.7–2.8]), and bupropion (n = 1,048) ROR = 2.2 (95% CI [2.1–2.4]) are least significantly associated with somnolence. Moreover, levomilnacipran (n = 1) ROR = 0.4 (95% CI [0.1–2.9]) was not associated with somnolence.

Conclusion

Among the thirty tested antidepressants, consistent with the original hypothesis, amoxepine has strongest 5-HT2C receptor binding affinity and has the highest reporting odds of somnolence. Atomoxetine, ranked second in reporting odds of somnolence overall, binds to the NET with with the strongest binding affinity among the thirty compounds. Mirtazapine, a tetracyclic antidepressant, was ranked 11th in reporting odds of somnolence and had the strongest H1 receptor binding affinity. This study provides an informative ranking of somnolence among thirty antidepressant compounds with an already wide array of clinical indications as well as provides insight into potential drug repurposing in psychopharmacology.
Codon optimization, expression in Escherichia coli, and immunogenicity analysis of deformed wing virus (DWV) structural protein
Authors: Fei Dongliang , Guo Yaxi , Fan Qiong , Li Ming , Sun Li , Ma Mingxiao , Li Yijing
Published: March 2020

Background

Deformed wing virus (DWV) is a serious threat to honey bees (Apis mellifera) and is considered a major cause of elevated losses of honey bee colonies. However, lack of information on the immunogenicity of DWV structural proteins has hindered the development of effective biocontrol drugs.

Methods

We optimized the VP1, VP2 and VP3 codons of DWV surface capsid protein genes on the basis of an Escherichia coli codon bias, and the optimized genes of roVP1, roVP2 and roVP3 were separately expressed in E. coli and purified. Next, the three recombinant proteins of roVP1, roVP2 and roVP3 were intramuscularly injected into BALB/c and the immunogenicity was evaluated by the levels of specific IgG and cytokines. Furthermore, anti-roVP-antisera (roVP1 or roVP2 or roVP3) from the immunized mice was incubated with DWV for injecting healthy white-eyed pupae for the viral challenge test, respectively.

Results

The optimized genes roVP1, roVP2 and roVP3 achieved the expression in E. coli using SDS-PAGE and Western blotting. Post-immunization, roVP2 and roVP3 exhibited higher immunogenicity than roVP1 and stimulated a stronger humoral immune response in the mice, which showed that the recombinant proteins of roVP3 and roVP2 induced a specific immune response in the mice. In the challenge test, data regarding quantitative real-time RT-PCR (qRT-PCR) from challenged pupae showed that the level of virus copies in the recombinant protein groups was significantly lower than that of the virus-only group at 96 h post-inoculation (P < 0.05). Among them, the degree of neutralization using antibodies raised to the recombinant proteins are between approximately 2-fold and 4-fold and the virus copies of the roVP3 group are the lowest in the three recombinant protein groups, which indicated that specific antibodies against recombinant proteins roVP1, roVP2 and roVP3 of DWV could neutralize DWV to reduce the virus titer in the pupae. Collectively, these results demonstrated that the surface capsid protein of DWV acted as candidates for the development of therapeutic antibodies against the virus.
The Ethnobotanical Survey, Antibacterial Activity and Phytochemical Screening of Extracts of Prosopis africana (Guill. & Perr.) Taub
Authors: Alimata Bance , Dofini Magnini René , Souleymane Compaore , Eli Compaore , Noufou Ouedraogo , Seydou Sourabie D. , Hassanata Millogo/Kone , Martin Kiendrebeogo
Published: March 2020

Aims: To investigate the ethnomedicinal uses of Prosopis africana (Guill. & Perr.) Taub and to screen the antimicrobial property as well as determine the phytochemical constituents of leaves, stems and root bark.

Study Design: Ethnobotanical surveys, antibacterial activity and phytochemical screening of extracts of P. africana.

Place and Duration of Study: The ethnobotanical survey was conducted during June 2015 in Zounweogo Province. The experiments were conducted at the Department of Medicine and Traditional Pharmacopeia-Pharmacy (MEPHATRA-PH) of the Institute of Research in Health and Laboratory of Applied Biochemistry and Chemistry (LA.BIO.C.A), University Joseph KI-ZERBO.

Methodology: The semi-structured questionnaires were administrated to 36 traditional healers and elucidated out on the ethnomedicinal uses of P. africana in treating bacterial infections, the plant parts used and the mode of administration. The antimicrobial activity of different polar extracts of the leaves, the stem and root were evaluated by using the agar diffusion method and the determination of the minimal inhibitory concentration (MIC) of extracts via microdilution method. The phytochemical constituents of all extracts were also screened air Ciulei method.

Results: The traditional healers consisted of 64% women and 36% men were surveyed.                 P. africana is used to treat tooth decay, childhood diarrhoea and chronic wounds. Leaves and the stem bark are the most commonly used plant part in treating bacterial infections while the roots are primarily used for other therapeutic purposes. The main method of administration was decoction. Methanol extracts of the leaves showed better antibacterial activity on all bacterial strains than aqueous extracts: Escherichia coli ATCC 25922 (MIC = 390 µg/ml; diameter of inhibition = 13.00 ±1.00 mm), Staphylococcus aureus ATCC 25923 (MIC = 390 µg/ml; diameter of inhibition = 12.33 ± 1.53 mm), Escherichia coli ATCC 35218 (MIC = 3120 µg/ml; diameter of inhibition = 13±1,00 mm), Pseudomonas aeruginosa PAO1 (MIC = 12500 µg/ml; diameter of inhibition = 12.33±0.58 mm). Alkaloid salts, tannins, sterols and triterpenes, saponosides, flavonic glycosides and leucoanthocyans were found in extracts of the leaves, as well as in the barks of the stem and root.

Conclusion: These results demonstrated that P. africana is a potent source of antimicrobial compounds and could justify its traditional use of in the folklore medicine of Zounweogo Province.
Inoculation of Wheat Plants with Pseudomonas spp. and Azospirillum brasilense under Drought Stress
Authors: Fioreze Samuel Luiz , Pinheiro Magaiver Gindri , Pereira Yriá Dias , Cruz Sonia Purin da
Published: March 2020

Aims: To investigate the effect of inoculation and co-inoculation of Pseudomonas spp. and Azospirillum brasilense on the morphophysiological characters of wheat (Triticum aestivum L.) under drought stress conditions.

Study Design: A randomized complete block design was used in a split plot scheme with four replicates. The plots consisted of irrigated and drought conditions. The subplots consisted of control (without inoculation), inoculation of Pseudomonas spp., inoculation of A. brasilense and co-inoculation of Pseudomonas spp. + A. brasilense. Liquid inoculant was used for two bacteria.

Place and Duration of Study: Agricultural Experimental Area of the Federal University of Santa Catarina, Campus of Curitibanos, SC, Brazil, between July and October 2018.

Methodology: Inoculation was performed at the time of sowing. Water deficit was characterized by irrigation suppression after plant emergence, considering a 25-day period without significant rainfall. At the end of the water restriction period, SPAD (Soil Plant Analysis Development) index and morphologic parameters of wheat plants was determined.

Results: Drought stress decreased dry matter accumulation of wheat plants, in terms of number of tillers, above ground dry matter and root-shoot ratio. Inoculation or co-inoculation with Pseudomonas spp. and A. brasilense did not affect plant growth. Under drought stress, SPAD index was higher in plants co-inoculated with Pseudomonas spp. and A. brasilense.

Conclusion: Although maintains SPAD index of wheat plants under drought stress, inoculation and co-inoculation with Pseudomonas spp. and A. brasilense do not influence the morphological characters of wheat plants.
Wavelength‐Tunable Mid‐Infrared Lasing from Black Phosphorus Nanosheets
Authors: Zhang Yushuang , Wang Shaowei , Chen Shula , Zhang Qinglin , Wang Xiao , Zhu Xiaoli , Zhang Xuehong , Xu Xing , Yang Tiefeng , He Mai , Yang Xin , Li Ziwei , Chen Xu , Wu Mingfei , Lu Yuerui , Ma Renmin , Lu Wei , Pan Anlian
Published: March 2020

Van der Waals layered semiconductor materials own unique physical properties and have attracted intense interest in developing high‐performance electronic and photonic devices. Among them, black phosphorus (BP) is distinct for its layer number‐tuned direct band gap which spans from near‐ to mid‐infrared (MIR) waveband. In addition, the puckered honey comb crystal lattice endows the material with highly linear‐polarized emission and marked anisotropy in carrier transportation. These unique material properties render BP as an intriguing and promising building block for constructing mid‐infrared‐ranged coherent light sources. Here, a room temperature surface‐emitting MIR laser based on single crystalline BP nanosheets coupled with a distributed Bragg reflector cavity is reported. MIR stimulated emission at 3611 nm is achieved with a near‐unity linear polarization, which exhibits robust thermal stability up to 360 K. Most importantly, the lasing wavelength can be tuned from 3425 to 4068 nm by varying the cavity length via thickness control of BP layer. The demonstrated highly polarized lasing output and wavelength‐tunable capacity of the proposed device scheme in MIR spectral range opens up promising opportunities for a broad array of applications in polarization‐resolved IR imaging, range‐finding, and free space quantum communications.
Highly Efficient Tandem White OLED Using a Hollow Structure
Authors: Han Kyung‐Hoon , Kim Kwan , Han Yoonjay , Kim Yang‐Doo , Lim Hyoungcheol , Huh Daihong , Shin Hyun , Lee Heon , Kim Jang‐Joo
Published: March 2020

A simple fabrication method for a light extraction layer is required. In this report, an internal light extraction layer composed of a high refractive index material and an air void is fabricated in five steps. A direct printing process followed by annealing of the randomly arrayed poly(benzyl methacrylate) pillars after a planarization process using TiO2‐nanoparticle dispersed resist and sol is used. These substrates are used for light extraction in white tandem organic light emitting diodes (WOLEDs). By combining the hollow structure and hemi‐spherical lens, WOLEDs without and with the light extraction structures are found to show maximum external quantum efficiencies of 35.6% and 103%, respectively. The power efficiencies at 100 cd m−2 of the WOLEDs without and with the light extraction structures are found to be 26.5 and 93.2 lm W−1, respectively. A color rendering index of 86.4, correlated color temperature of 4860 K, and CIE of (0.353, 0.389) are achieved in the WOLEDs with light extraction structures.
Ferromagnetic Order at Room Temperature in Monolayer WSe2 Semiconductor via Vanadium Dopant
Authors: Yun Seok Joon , Duong Dinh Loc , Ha Doan Manh , Singh Kirandeep , Phan Thanh Luan , Choi Wooseon , Kim Young‐Min , Lee Young Hee
Published: March 2020

Diluted magnetic semiconductors including Mn‐doped GaAs are attractive for gate‐controlled spintronics but Curie transition at room temperature with long‐range ferromagnetic order is still debatable to date. Here, the room‐temperature ferromagnetic domains with long‐range order in semiconducting V‐doped WSe2 monolayer synthesized by chemical vapor deposition are reported. Ferromagnetic order is manifested using magnetic force microscopy up to 360 K, while retaining high on/off current ratio of ≈105 at 0.1% V‐doping concentration. The V‐substitution to W sites keeps a V–V separation distance of 5 nm without V–V aggregation, scrutinized by high‐resolution scanning transmission electron microscopy. More importantly, the ferromagnetic order is clearly modulated by applying a back‐gate bias. The findings open new opportunities for using 2D transition metal dichalcogenides for future spintronics.
A Biomimetic Plasmonic Nanoreactor for Reliable Metabolite Detection
Authors: Liu Jiangang , Cai Chenlei , Wang Yuning , Liu Yu , Huang Lin , Tian Tongtong , Yao Yuanyuan , Wei Jia , Chen Ruoping , Zhang Kun , Liu Baohong , Qian Kun
Published: March 2020

Reliable monitoring of metabolites in biofluids is critical for diagnosis, treatment, and long‐term management of various diseases. Although widely used, existing enzymatic metabolite assays face challenges in clinical practice primarily due to the susceptibility of enzyme activity to external conditions and the low sensitivity of sensing strategies. Inspired by the micro/nanoscale confined catalytic environment in living cells, the coencapsulation of oxidoreductase and metal nanoparticles within the nanopores of macroporous silica foams to fabricate all‐in‐one bio‐nanoreactors is reported herein for use in surface‐enhanced Raman scattering (SERS)‐based metabolic assays. The enhancement of catalytical activity and stability of enzyme against high temperatures, long‐time storage or proteolytic agents are demonstrated. The nanoreactors recognize and catalyze oxidation of the metabolite, and provide ratiometric SERS response in the presence of the enzymatic by‐product H2O2, enabling sensitive metabolite quantification in a “sample in and answer out” manner. The nanoreactor makes any oxidoreductase‐responsible metabolite a candidate for quantitative SERS sensing, as shown for glucose and lactate. Glucose levels of patients with bacterial infection are accurately analyzed with only 20 µL of cerebrospinal fluids, indicating the potential application of the nanoreactor in vitro clinical testing.
Sand topdressing and protective covers impact creeping bentgrass crown moisture during winter
Authors: Michael Darrell J. , Kreuser William C.
Published: March 2020

Winter desiccation injury can severely impact golf courses in the northern and central Great Plains. While it is well‐established that turfgrass crown moisture content (CMC) declines during fall cold‐acclimation, little is known about CMC during winter desiccation stress and how management practices influence CMC during desiccation stress. The objectives of this study were to understand how protective covers, sand topdressing, and spray‐applied treatments impact creeping bentgrass (Agrostis stolonifera) CMC and spring green‐up following winter desiccation stress in Nebraska. Spray‐applied treatments included a turf colorant, horticultural oil plus colorant, anti‐transpirant, and a fall applied soil wetting agent. Crown moisture content was measured monthly from December to March at Mead, NE and after winter in Axtell, NE. Visual turfgrass quality ratings were used to monitor survival and spring regrowth. Late‐fall sand topdressing and permeable and impermeable protective covers reduced winter desiccation injury compared to a non‐treated plot. Turfgrass CMC ranged from 0.251 to 0.764 g H2O g−1 fresh weight (FW) depending on treatment and location. Logistic regression indicated that turf plants with a CMC of 0.518 g H2O g−1 FW had a 50% probability of significant winter desiccation injury. Under severe desiccation pressure, the spray‐applied treatments did not prevent winter desiccation injury. Under these circumstances, a majority of plots receiving spray‐applied treatments had a March CMC of less than 0.500 g H2O g−1. Physical protection of turfgrass crowns with covers or sand topdressing in late fall sustained CMC during late‐winter and decreased the potential for winter desiccation injury the following spring.
Winter wheat nitrogen utilization under different mulching practices on the Loess Plateau
Authors: Chen Xiuwen , Zhao Hubing , Liu Jifei , Mao Anran
Published: March 2020

Winter wheat (Triticum aestivum L.) is one of the most important cereal crops in the world, and mulching is mostly practiced in the semi‐arid region of Northwest China. We examined the effect of different mulching practices on soil N, plant N uptake, N use efficiency and yield of wheat with similar fertilizer rate. The experiment was conducted for 5 yr with four replicates. The five practices included: Control (CK), nitrogen fertilizer and no mulching (NM), nitrogen fertilizer plus plastic film mulching (PM), nitrogen fertilizer plus ridge mulching and furrow seeding (RM+FS), and nitrogen fertilizer plus straw mulching (SM). We found that yield and biomass of winter wheat were significantly affected by different mulching practices during the five growing seasons. Compared to the NM treatment, the PM, SM, and RM+FS treatments increased grain yield by 13, 9, and 4%, respectively, and biomass by 19, 13, and 10%, respectively. Compared to the NM, the RM+FS and PM treatments tended to decrease average grain, straw, and chaff N concentration, while straw mulching tended to increase average grain, straw, and chaff N concentration. Compared to the NM treatment, all mulching treatments consistently increased NUE, and straw mulching had the most significant effect. Nitrate‐N in the NM was most likely to leach into deep layers, followed by the SM and the lowest nitrate‐N leaching risk was in the two plastic film mulching treatments. The PM could increase winter wheat yield and decrease the risk of nitrate‐N leaching. Thus, PM performed better among the mulching practices.
Massive pneumoperitoneum with abdominal pain and fever mimicking delayed perforation following endoscopic resection: A case report
Authors: Yeh Jen‐Hao , Chen Jen‐Chieh , Hsu Chia‐Chang , Wang Wen‐Lun , Lin Chih‐Wen
Published: March 2020

Pneumoperitoneum has been reported as an intraprocedural or acute postprocedural adverse event resulting from advanced endoscopic intervention. Here, we report a case of a massive pneumoperitoneum‐mimicking delayed perforation after colonic endoscopic submucosal dissection. A 60‐year‐old man received endoscopic submucosal dissection for a large colon polyp. Room air was inadvertently used in the first half of the procedure. After 12 hours, the patient developed fever, abdominal pain, and bilateral shoulder pain, and massive pneumoperitoneum was detected through plain film and computed tomography. After urgent diagnostic paracentesis, the patient's symptoms dramatically improved, and laparotomy was avoided. Massive pneumoperitoneum rarely occurs in patients receiving complex and long‐standing endoscopic procedures, and it may manifest similarly to delayed perforation. Prompt diagnostic paracentesis is valuable when the diagnosis is uncertain.
Outcomes of pregnancy in Child A liver cirrhotic patients: A retrospective multicenter study
Authors: Salman Ahmed Abdallah , Kasem Mohamed Fikry , Kholaif Khaled M. , Ramadan Mohamed , Yousef Mohamed , Shaaban Hossam El‐Din , Atallah Mohamed , El Sherbiny Mohammad , Ashoush Omar , Seif El Nasr Sayed M
Published: March 2020

Only few studies reported the impact of Child A cirrhosis on pregnancy outcomes. Therefore, we aimed to assess the outcomes of pregnancy in Child A cirrhotic patients compared to noncirrhotic pregnant females in terms of maternal and neonatal outcomes. The present retrospective study was conducted from January 2013 till January 2018. Pregnant females with Child A cirrhosis and age and gestational age‐matched, noncirrhotic pregnant women were included. The main aim of this work was the differences in the pregnancy‐related outcomes between both studied groups. The present study included 100 pregnant cirrhotic women and 100 pregnant noncirrhotic women as a control group. In terms of the association between the presence of cirrhosis and maternal outcomes. The incidence of preeclampsia in the cirrhotic group was 6% in comparison to 2% in the noncirrhotic group (P = .27). On the other hand, 35% of women in the cirrhosis group underwent cesarean section (CS) delivery compared to 20% only in the noncirrhotic group (P = .018). Regarding neonatal outcomes, the incidence of preterm delivery and low birth weight were notably higher in the cirrhotic group than the noncirrhotic group (25% vs 7%, 15% vs 6% and P = .001, and 0.038). In contrary, there were no statistically significant variations between both groups in terms of stillbirth (P = .72), small for gestational age (P = .33), malformation (P = .99), and neonatal death (P = .99). Child A cirrhosis appears to increase the risks of prematurity, low birth weight and CS delivery; while it has no impact on maternal or neonatal mortality.
Oleogel Fabrication Based on Sodium Caseinate, Hydroxypropyl Methylcellulose, and Beeswax: Effect of Concentration, Oleogelation Method, and Their Optimization
Authors: Alizadeh Leyla , Abdolmaleki Khadije , Nayebzadeh Kooshan , Hosseini Seyede Marzieh
Published: March 2020

In the present study, the oleogel preparation with hydroxypropyl methylcellulose (HPMC) (0–2 g/100 g), sodium caseinate (CN) (0–4 g/100 g), beeswax (0–5 g/100 g), and oleogelation method (foam and emulsion template) was optimized using response surface methodology (RSM) to attain the desirable oil retaining ability, rheological, and textural characteristics. For all the chosen responses, the quadratic model was the best‐fitting model with a determination coefficient of R2 > 0.91. Results exhibited that the HPMC and CN concentrations were the most influential tested factors on the oil binding capacity, textural, and rheological characteristics of the oleogels due to the formation of more complex and strong network. There was a significant improvement in oil binding capacity and structure recovery of samples by beeswax addition. To produce oleogel similar to industrial shortening, the optimization method was done based on maximum oil binding capacity and thixotropic recovery and other responses were chosen equal to those of shortening values (ɳa = 330 Pa.s, G′ = 276,543 Pa, A value = 164,308 Pa s rad−1, and firmness = 44.99 g). As regards the optimized level of structuring agents and responses (ɳa = 317 and 329 Pa.s, G′ = 249,782 and 260,997 Pa, A value = 180,022 and 180,373 Pa s rad−1, and firmness = 44.37 and 36.98 g corresponding to Optimization 1 and Optimization 2, respectively), fabrication of oleogels with at least 90 g/100 g trans‐free and low saturated oil and attributes close to industrial shortening is possible.
Early detection of high disease activity in juvenile idiopathic arthritis by sequential monitoring of patients' health‐related quality of life scores
Authors: You Lu , Qiu Andrew , Huang Bin , Qiu Peihua
Published: March 2020

Juvenile idiopathic arthritis (JIA) is a chronic disease. During its “high disease activity (HDA)” stage, JIA can cause severe pain, and thus could seriously affect patients' physical and psychological health. Early detection of the HDA stage of JIA can reduce the damage of the disease by treating it at an early stage and alleviating the painful experience of the patients. So far, no effective cure of JIA has been found, and one major goal of disease management is to improve patients' quality of life. To this end, patients' health‐related quality of life (HRQOL) scores are routinely collected over time from JIA patients. In this paper, we demonstrate that a new statistical methodology called dynamic screening system (DySS) is effective for early detection of the HDA stage of JIA. By this approach, a patient's HRQOL scores are monitored sequentially, and a signal is given by DySS once the longitudinal pattern of the scores is found to be significantly different from the pattern of patients with low disease activity. Dimension reduction of the observed HRQOL scores and the corresponding impact on the performance of DySS are also discussed.