bluuebunny/crossref_metadata_2025 huggingface dataset:
Plasma Calcitonin Gene-Related Peptide Levels in Idiopathic Intracranial Hypertension: An Exploratory Study
Authors: Krajnc Nik , Frank Florian , Macher Stefan , Michl Martin , Müller Nina , Maier Sarah , Zaic Sina , Wöber Christian , Pemp Berthold , Broessner Gregor , Bsteh Gabriel
Published: March 2024

Background.
Idiopathic intracranial hypertension (IIH) is a debilitating condition characterized by increased intracranial pressure often presenting with chronic migraine-like headache. Calcitonin gene-related peptide (CGRP) plays an important pathophysiological role in primary headaches such as migraine and cluster headache, whilst its role in IIH has not yet been established.
Methods.
This longitudinal exploratory study included patients with definite IIH (pwIIH), episodic migraine (EM) in a headache-free interval and healthy controls (HC). Blood samples were collected from a cubital vein and plasma CGRP (pCGRP) levels were measured by standardized ELISA.
Results.
A total of 26 pwIIH (mean age 33.2 years [SD 9.2], 88.5% female, median BMI 34.8 kg/m2 [IQR 30.0–41.4]), 30 patients with EM (mean age 27.6 years [7.5], 66.7% female) and 57 HC (mean age 25.3 years [5.2], 56.1% female) were included. pCGRP levels displayed a wide variation in IIH as well as in EM and HC on a group-level. Within pwIIH, those with migraine-like headache had significantly higher pCGRP levels than those with non-migraine-like headache (F(2,524) = 84.79; p < 0.001) and headache absence (F(2,524) = 84.79; p < 0.001) throughout the observation period, explaining 14.7% of the variance in pCGRP levels. CGRP measurements showed strong intraindividual agreement in pwIIH (ICC 0.993, 95% CI 0.987–0.996, p < 0.001). No association was found between pCGRP levels and ophthalmological parameters.
Conclusions.
Although interindividual heterogeneity of pCGRP levels is generally high, migraine-like headache seems to be associated with higher pCGRP levels. CGRP may play a role in the headache pathophysiology at least in a subgroup of IIH.
General vertex-degree-based topological indices of Graphene Oxide (C 140 H 42 O 20 ) graphs with advanced entropies
Authors: Kamran Muhammad , Salamat Nadeem , Nadeem Muhammad , CANGUL Ismail Naci , Farman Muhammad
Published: March 2024

Nanomaterials have been widely used in a number of sectors during the past few decades, including electronics, pharmaceuticals , cosmetics, food processing, construction, and aeronautics. These nanomaterials may improve approaches for therapy, diagnosis, and prevention in the medical field. Graphene oxide (GO), an oxidised derivative of graphene, is now used in biotechnology and medicine for the treatment of cancer, drug delivery, and cellular imaging. Large surface area, electrical charge, and nanoscale size are other physicochemical properties of GO. The factors that are crucial for QSAR and QSPR analyses are topological indices. Shannon’s entropy measures, which characterise graphs by looking at the structure information of graphs and networks, are the primary type of topological indices now in use.Graph theory, biology, and chemistry are just a few of the disciplines that employ the graph entropy measurements. Two examples of thermodynamic entropy utilised in the molecular dynamics research of complicated chemical systems are the configuration entropy of glass-forming liquids or the thermodynamic entropy of enzyme-substrate complexations. In this paper, several degree-based entropies calculated using topological indices. The required outcomes were obtained by combining curve fitting between determined information entropies and topological indices with numerical and graphical representations of computed findings. Learn about the entropy-based symmetry analysis of the topological indices. The system is based on topological indices, which offer a thorough overview of all potentially important factors that may be important in structurally changing (C140H42O20) for certain applications.
Mathematics Subject Classification: 05C09, 05C92, 05C07, 92E10
Amino Acids Composition of V. Doniana and S. Comorensis Fruits
Authors: Charles Dominic , MGINA CLARENCE
Published: March 2024

The amino acids composition of S. comorensis and V. doniana fruits were investigated in this study. The analysis was done using Liquid Chromatography - Mass Spectrometry (LC-MS). It was found that the various essential amino acids in S. comorensis fruits ranged from 0.01 ± 0.18 mg/kg to 55.01 ± 2.15 mg/kg and V. doniana fruits ranged from 0.023 ± 0.00 mg/kg to 88.64 ± 0.87 mg/kg. For each of the plant fruits there were no significant differences in terms of amino acids amounts between the two regions (P > 0.05) except for phenylalanine in V. doniana. The phenylalanine content in V. doniana ranged from 51.36 mg/kg to 53.14 mg/kg for the fruit samples from Pwani and 39.61 mg/kg to 39.87 mg/kg for the fruit samples from Tanga with a significant difference between the two regions {P < 0.05). Leucine was the most abundant essential amino acid in S. comorensis fruits with a range between 44.78 mg/kg and 51.42 mg/kg for the fruit samples from Tanga region and 52.86 mg/kg to 57.16 mg/kg for the fruit’s samples from Pwani region with no significant difference (P > 0.05) in content between two regions. It was notable that lysine, histidine and threonine ware not detected in any of the samples from the two species. The study shows that these fruits are potential essential amino acids food sources and can complement with other sources to make a balanced diet for a healthy human body.
Novel double structural transition at room temperature in Bi1-xGdxFeO3 system prepared by sol-gel method
Authors: Dinia S. , El-Bey A. , Oubla M. , Taibi M. , Elbahraoui T. , Atourki L. , Belayachi W. , Abd-Lefdil M.
Published: March 2024

Bi1-xGdxFeO3 \(\text{p}\text{o}\text{w}\text{d}\text{e}\text{r}\text{s} \text{w}\text{i}\text{t}\text{h} 0.00\le x\le 0.20\) were successfully synthesized by sol-gel process. X-ray analyses revealed the existence of a double structural transition from rhombohedral to cubic symmetry for \(x=0.10\) (first transition) and from cubic to orthorhombic symmetry for \(x\ge 0.15\) (second transition). Infrared spectroscopy allows the identification of different bending and stretching vibrations between the different ions. Magnetization hysteresis loops, recorded at room temperature, indicate a typical ferromagnetic-like behaviour. Additionally, differential scanning calorimetry measurements were also performed and discussed.
Genetic risk assessment of HLA DRB1 alleles (01, 04, 12 and 15) with Rheumatoid arthritis susceptibility among the Pashtun population of Khyber Pakhtunkhwa, Pakistan
Authors: Ilahi Zahoor , Khan Najeeb Ullah , Khan Hamza , Almutairi Mikhlid H. , Ali Ijaz
Published: March 2024

Background: Rheumatoid arthritis (RA) is a chronic autoimmune condition influenced by a complex interplay of genetic and environmental factors. Specific genetic variations, particularly in the human leukocyte antigen (HLA)-DRB1 gene, have been strongly linked to RA susceptibility. HLA-DRB1 alleles, part of the major histocompatibility complex (MHC) class II gene family, play a significant role in the immune system.
Aims: This study aimed to investigate the association between HLA-DRB1*01, *04, *12, and *15 alleles and RA risk within the Pashtun population of Pakistan.
Methods: A cohort of 100 RA patients and 80 healthy controls was recruited for this study. DNA was isolated from blood samples using the salting-out method, followed by genotyping using sequence-specific primer polymerase chain reaction (SSP-PCR). The association of the selected alleles with clinicopathological and demographic parameters of RA was assessed using the Medcalc odds ratio calculator and Chi-square test.
Results: Allelic and genotypic analysis revealed that HLA-DRB1 *01 and *04 variants exhibited non-significant associations with RA risk (P=0.1421 and 0.8495, respectively). Similarly, mutant genotypes of HLA-DRB1 *01 and *04 showed non-significant associations with RA (P=0.2922 and P=0.8263, respectively). However, the heterozygous CA genotype of HLA-DRB1 *01 demonstrated a significant association with RA (P=0.0004), whereas HLA-DRB1 *04 did not (P=0.9120). Furthermore, HLA-DRB1 *12 showed a significant association with increased RA risk (P=0.0001), while HLA-DRB1 *15 did not (P=0.5519). Additionally, HLA-DRB1*01, *04, and *12 did not show significant associations with age group (P=0.08, P=0.11, P=0.16) and rheumatoid factor (RF) status (P=0.34, P=0.65, and P=0.74), whereas HLA-DRB1 *15 exhibited non-significant associations with age group and RF (P=0.01 each). Moreover, associations of HLA-DRB1 *01, *04, *12, and *15 with gender (P=0.81, P=0.52, P=0.27, and P=0.09, respectively) and anti-citrullinated protein antibody (ACPA) status (P=0.56, P=0.40, P=0.65, and P=0.008, respectively) were not significant, except for HLA-DRB1 *04, which displayed a significant association with ACPA.
Conclusion: HLA-DRB1 *12 and heterozygous genotypes of HLA-DRB1 *01 were significantly associated with RA risk in the Pashtun population. However, further analysis utilizing whole exome sequencing with larger datasets is warranted for more precise results.
Based on improved YOLOv8 and Bot SORT surveillance video traffic statistics
Authors: Yang Yiqun , Pi Daneng , Wang Lingyan , Bao Mingliang , Ge Jianfu , Yuan Tingchen , Yu Houshi , Zhou Qi
Published: March 2024

Aiming at the problems of leakage detection and low detection accuracy of existing deep learning based surveillance video traffic flow detection algorithms, a traffic flow counting system combining improved YOLOv8 detection and Bot SORT tracking is proposed. First, the backbone network is used to incorporate the SPD-Conv convolutional layer to improve the network's ability to detect small targets. Then, the attention mechanism CoTAttention is introduced into the neck network to further improve the model generalization ability. Finally, the improved YOLOv8 model and the Bot SORT algorithm are combined to design and implement a traffic counting system capable of monitoring video traffic in real time, and trained and tested on the open-source UA-DETRAC vehicle detection dataset. The experimental results show that the improved YOLOv8 algorithm improves F1, P, mAP50, and mAP50-95 by 0.36, 2.2, 1.8, and 2.1 percentage points, respectively, compared with the original algorithm. Combined with the Bot SORT tracking, it achieves more accurate and reliable results in the task of traffic counting, which provides a strong support for the vehicle detection and counting in the monitoring system.
A Task Offloading Decision and Resource Allocation Algorithm Based on DDPG in Mobile Edge Computing
Authors: Li An , Zheng Yeqiang , Nong Wang , Wang Gaocai , Huang Shuqiang
Published: March 2024

In mobile edge computing, the mobile device can offload tasks to the server near the edge of the mobile network for execution, thereby reducing the delay of task execution and the energy consumption of mobile device. However, limited resource of the edge server prevents the mobile device to offload all tasks to the edge servers for execution. To solve the problems, a mobile edge computing model of multi-users and single edge server is constructed in this paper. In order to minimize the weighted total cost composed of mobile device energy consumption and time delay under the constraints of task execution delay, computing resource and storage resource of the edge server, we propose a task offloading decision and resource allocation algorithm OADDPG based on Deep Deterministic Policy Gradient (DDPG). A special reward function is designed to make the reward value for correlating negatively with the total cost. We can get the lowest total cost when the algorithm reaches the maximum reward value. Experiment results show that the proposed algorithm can effectively reduce the weighted total cost of mobile devices and improve the success rate of task execution.
Impact of research and development expenses on the profitability of assets: The case of textile and clothing industry in Portugal
Authors: de Moraes e Soares Ricardo , Morais Nunes Alexandre , Heliodoro Paula , Martins Vanda
Published: March 2024

The study aims to examine the financial efficiency of the textile and clothing industries in Portugal using official statistical data. The main objective is to assess the relationship between spending on research and development and return on assets. The study analyzes the performance of various subsectors of the textile and clothing industries, presenting the relationship between investments in research and development and the operating return on assets over various economic periods. The study adopted data envelopment analysis, classifying decision-making units based on average efficiency levels. The results highlight sectors of manufacture of textiles for technical and industrial use, manufacture of other textiles, production of outerwear, and manufacture of workwear as the most efficient. In contrast, sectors of manufacture of clothing and accessories, manufacture of knitwear, and leather clothing show lower levels of efficiency. From 2003 to 2022, the textile industry exhibited the highest levels of financial efficiency, with an above-average ratio between spending on research and development and return on assets. However, sectors of knitwear manufacturing and textile finishing have maintained a more or less constant level of financial efficiency. The analysis highlights the need for targeted interventions to increase the financial efficiency of different subsectors within the textile and clothing industries. It is evident that there are varying levels of financial efficiency across these sectors, and the need for benchmarking periods can help identify areas for improvement and set achievable goals.
AcknowledgmentThis article is financed by Instituto Politécnico de Setúbal [Polytechnic Institute of Setúbal].
Modeling on comprehensive evaluation of groundwater quality status using Geographic Information System (GIS) and Water Quality Index (WQI): a case study of Bahir Dar City, Amhara, Ethiopia
Authors: Alemu Chalachew Mulat , Aycheh Yibeltal Fentahun , Angualie Gashaw Sintayehu , Engidayehu Selamawit Sewunet
Published: March 2024

Groundwater is the most important natural resource, and many people throughout the world rely on it for drinking, particularly in rural areas. The present study was carried out to assess the status of groundwater quality and to check its suitability for domestic purposes in urban centres of Bahir Dar City, Ethiopia. Twelve shallow wells were selected for sampling. The sampled water was taken during the dry and summer seasons of the year 2019/2020. pH, turbidity, EC, TDS, chloride (Cl−), nitrate (NO3−), phosphate (PO4−3), total hardness, and Escherichia coli were measured for the suitability analysis. Comparison of measured results with those of WHO and Ethiopian drinking water quality standards was done. Moreover, Geographic Information System (GIS) and Water Quality Index (WQI) data analysis techniques were applied in order to investigate the groundwater quality. The spatial distribution map showed that the city's core area had the poorest groundwater quality status. The WQI result obtained from the analysis showed that 41.67, 33.33, and 25% of the sampled groundwater has low, extremely poor, and unsafe quality for drinking purposes, respectively. The present study revealed that anthropogenic activities have a great impact on the quality of groundwater in the area, necessitating immediate mitigating actions.
Development of Banking Card Market in Russia in Territorial View
Authors: Lapteva E. V.
Published: March 2024

The article highlights the growing frequency of using bank cards and analyzes the difference in their use subject to the region. According to statistics, in 2022 on Russian market 88% fell on payment cards. A steady growth in the number of bank cards was observed for 10 years both with individuals and legal entities. Individuals prevail among bank card users, their share in 2022 reached 98.2%. As technologies develop and new technical solutions turn up bank cards become more accessible for customers and today there are various types of payment cards meeting different needs and preferences of users. Regional distribution of bank cards in Russia was not equal. The leading position by payment card issuance is taken by the Central Federal Region, where 136.9m cards (34.5%) were issued in 2022. The second position is taken by the Volga Federal Region – 71.4m cards or 18.0%, the third position – by the Siberian Federal Region with 43.1m cards or 10.9%. The author showed that the number and the volume of transactions made by cards during the last decade demonstrate steady growing trend both in the country and in federal regions.
Scientific Approaches to Explore the Essence of the Technological Sovereignty of the Economy
Authors: Nevyantseva L. S.
Published: March 2024

On the current stage of economic and geo-political development of the country, that can be characterized by weakening of foreign-economic relations with unfriendly countries, sanctions against Russian economy and blocking the access to import technologies strategically important for Russian production, issues dealing with Russian economy arrival on the advanced technological level become more and more acute. Ensuring technological sovereignty of national economy in crucial industries is a top-priority task for attaining this goal and academic research of technological sovereignty is especially topical today. Thus, the present article studies essential and conceptual characteristics of economy technological sovereignty. By analyzing academic literature the author identified three scientific and practical approaches to understanding the essence of technological sovereignty: technological sovereignty as a component of economic and national security; technological sovereignty as an element of open-type economy; technological sovereignty as a factor of geo-political development and as a level of science and technological development collated with global one. The article shows strategic basis of technological sovereignty in Russia. And finally, the author came to the conclusion that the vector of Russian economy development combined with achieving technological independence of national economy is strategically true.
Technological Development of Industry Based on Integration of Science, Business and State
Authors: Kochetova O. O.
Published: March 2024

The article studies principle reasons for technological underdevelopment of Russia compared with western countries and identifies regulatory documents aimed at finding promising ways to resolve this problem. Analysis of the numerous academic works investigating issues of innovation development of industry, importance of scientific and technical progress for economic growth, cooperation between universities and industrial enterprises provides an opportunity to substantiate topicality of the research. The author on the basis of different interpretations of the notion ‘technological development’ could formulate his own definition. Further on, a conclusion was drawn that universities, industrial enterprises and state are actors of technological development. The author built a model and mechanisms of organizational and technical interaction of representatives of science, business and state. The project ‘Advanced Engineering Schools’ is an example of such interaction aimed at providing industry with highly-qualified engineers. Research findings are tested through the mechanism of scientific and industrial integration of the company ODK, the St. Petersburg Polytechnic University and state. The author’s developments have practical significance, as they can be used in education, at industrial enterprises and in other sectors of economy for planning programs of technological modernization in industry.
Congenital Abdominal Aortic Aneurysm: Presentation, Etiology, Diagnosis and
Management
Authors: Al-Askari Majd R. , Patni Mohamed Anas Mohamed Faruk , Krayem Yaman , Ejaz Abdullah
Published: March 2024

Aortic aneurysms are common in adults due to atherosclerosis but are rare in children and young adults, often overlooked due to infrequent
reporting. Acquired aneurysms are usually linked to factors like umbilical artery ligation, connective tissue diseases, or vasculitides. In contrast, the
causes of congenital abdominal aortic aneurysms (AAA) remain unknown due to their extreme rarity. Only a few cases have been reported. Prompt
diagnosis is essential when symptoms such as abdominal distention, vomiting, or abdominal pulsatility occur. Diagnosis is typically confirmed
through ultrasonography and multi-slice spiral computed tomography angiographies (MCSTA). After detection, a comprehensive investigation is
necessary to rule out acquired AAA causes. Managing congenital AAA requires a highly personalized approach, with early surgical repair using
grafts as a recommended option. After an extensive analysis of numerous academic sources, we have comprehensively understood the
epidemiology, clinical features, and diagnostic and treatment techniques for congenital abdominal aortic aneurysms.
Green Synthesis of Biorelevant Scaffolds through Organocatalytic/ Enzymatic Dynamic Kinetic Resolution
Authors: Pellissier Helene
Published: March 2024

This review highlights major developments in the application of green organocatalytic
and enzymatic dynamic kinetic resolutions (DKRs) in the total synthesis of biorelevant scaffolds.
It illustrates the diversity of useful bioactive products and intermediates that can be synthesized
under greener and more economic conditions through the combination of the powerful concept of
DKR, which allows the resolution of racemic compounds with up to 100% yield, with either
asymmetric organocatalysis or enzymatic catalysis, avoiding the use of toxic and expensive metals.
With the need for more ecologic synthetic technologies, this field will undoubtedly expand its
scope in the future with the employment of other organocatalysts/enzymes to even more types of
transformations, thus allowing powerful greener and more economic strategies to reach other biologically
important molecules.
A Novel Electrochemiluminescence (ECL) Immunoassay for the Quantitation
of Monoclonal Antibody (mAb) PYX-106 in Human Serum
Authors: Yin Feng , Adhikari Diana , Liu Xiaodong F. , Wang Jianxin , Yang Wensheng , Balogh Gabriela A. , Simon Teri , Lei Wenji , Squicciarini Mariana , Bruce Lisa , Ke Yan , Dyszel Mike , Harriman Shawn , Pinkas Jan
Published: March 2024

Background::

PYX-106 is a novel monoclonal antibody (mAb), targeting the sialic acidbinding
immunoglobulin-like lectin 15 (Siglec-15) in the Tumor Microenvironment (TME). Precise
measurement of PYX-106 is essential for the thorough assessment of PYX-106 pharmacokinetics
in clinical investigations.

Methods::

A novel Electrochemiluminescence (ECL) immunoassay for the quantitation of PYX-
106 in human serum was developed and validated. Biotinylated anti-PYX-106 antibody Bio-A1A1
was employed as the capture antibody, and ruthenylated anti-PYX-106 antibody Ru-A3G10 was
utilized as the detection antibody in the ECL immunoassay on Meso Scale Discovery (MSD) platform.

Results::

This assay was fully validated in terms of selectivity, accuracy, precision, hook effect,
stability, etc., with a dynamic range from 50.0 to 2,500 ng/mL in human serum under the 2018
U.S. Food and Drug Administration (FDA) guidance and the 2022 U.S. FDA ICH M10 guidance.

Conclusion::

PYX-106 bioanalytical assay validation was reported for the first time in a biological
matrix, and this assay has been successfully applied to support a clinical trial PYX-106-101.
Urinary Tract Infection by Aspergillus Species in Post-Menopausal Woman
Authors: Shukla Manisha , Vishwakarma Rohit Kumar , Chauhan Neha
Published: March 2024

Background:

Urinary tract infection by Aspergillus species is an uncommon but potentially serious complication in post-menopausal women, often associated
with recurrent UTIs or immunocompromise.

Case Presentation:

We present a case of a deceased 67-year-old female with complaints of fever, abdominal pain, diabetes, hypertension, pain and burning during
urination admitted to hospital. Microscopic examination confirmed the Aspergillus infection. The patient could not be followed up due to COVID.

Discussion:

Urinary Tract infection with Aspergillus species is few and far occurrence. Especially combined with a medical history of non-immune
compromises like diabetes, kidney dysfunction and hypertension. Voriconazole anti-fungal medicine worked well on patients with improved
conditions. In spite of diabetes and other medical conditions, neutrophils and total lymphocyte count showed elevated levels, which need further
studies.

Conclusion:

Prompt diagnosis and targeted antifungal therapy are essential in managing urinary tract infections caused by Aspergillus species in postmenopausal
women to prevent complications.
DAMPAK APLIKASI MIKORIZA TERHADAP PERTUMBUHAN DAN PERKEMBANGAN PENYAKIT JAMUR AKAR PUTIH (Rigidoporus microporus) PADA BIBIT KARET (Hevea brasiliensis)
Authors: Istiqomah Fatimah Nur , Novanto Praditya Rizqi , Janati Rahayu Ning
Published: March 2024

Penyakit Jamur Akar Putih (JAP) pada tanaman karet menimbulkan kerugian yang cukup besar. Upaya pencegahan dini diperlukan dengan menggunakan agens hayati mikoriza pada bibit karet. Penelitian dilakukan di greenhouse menggunakan Rancangan Acak Kelompok Lengkap (RAKL) terdiri dari 10 kombinasi perlakuan mikoriza (granul dan kapsul) dan JAP. Pengamatan dilakukan sampai umur 24 MST dan data penelitian diolah menggunakan uji jarak berganda Duncan pada taraf 5%. Hasil penelitian menunjukkan bahwa perlakuan mikoriza granul 10 g dan 20 g maupun mikoriza kapsul dosis 1 dan 2 pcs dapat meningkatkan pertambahan tinggi dan diameter bibit karet dibandingkan dengan kontrol dan perlakuan JAP. Infeksi akar mikoriza paling tinggi terdapat pada perlakuan mikoriza granul 20 g dan mikoriza kapsul 2 pcs + JAP dengan nilai infeksi akar tergolong sedang yaitu 50%. Intensitas penyakit JAP paling tinggi ditemukan pada perlakuan JAP tanpa mikoriza yaitu 8,33%, sedangkan perlakuan mikoriza yang ditambah JAP memiliki intensitas penyakit JAP lebih rendah yaitu rata-rata 2%. Aplikasi mikoriza di awal tanam mampu mencegah serangan penyakit JAP pada bibit karet.
Dziecko hospitalizowane z powodu obturacyjnego zapalenia oskrzeli - studium indywidualnego przypadku
Authors: Waligórska Martyna
Published: March 2024

Wstęp. Obturacyjne zapalenie oskrzeli to charakterystyczna postać zakażenia układu oddechowego. Dochodzi do zwężenia światła oskrzeli oraz nadprodukcji śluzu w drogach oddechowych, w wyniku czego występuje duszność stanowiąca zagrożenie życia dziecka. Objawy zapalenia mogą być różne w zależności od czynnika etiologicznego wywołującego chorobę. Do głównych objawów należą kaszel, stany podgorączkowe, nasilony obrzęk dróg oddechowych, duszność oraz zwiększone gromadzenie wydzieliny śluzowej. Zapalenie oskrzeli z obturacją częściej diagnozuje się u dzieci ze względu na ich niedojrzałość układu oddechowego oraz niewykształconą odporność. Najwięcej zachorowań występuje w przypadku dzieci uczęszczających do przedszkola czy żłobka. Częstym zjawiskiem są nawroty choroby, głównie w okresie jesienno-zimowym.

Cel. Celem niniejszej pracy jest przedstawienie zakresu zadań pielęgniarki pediatrycznej, zastosowanych wobec dziecka z obturacyjnym zapaleniem oskrzeli oraz zaprezentowanie problemów pielęgnacyjnych, wynikających z choroby.

Prezentacja przypadku. Chłopiec, 6-miesięczny, przyjęty w oddział pediatryczny w stanie ogólnym średnim w pierwszej dobie hospitalizacji z powodu duszności wydechowej oraz utrzymującej się podwyższonej temperatury ciała. Z przeprowadzonych badań laboratoryjnych zgodnie ze zleceniem lekarskim uzyskano podwyższone wskaźniki odpowiedzialne za stan zapalny w organizmie. U chłopca zdiagnozowano obturacyjne zapalenie oskrzeli. Od kilku dni występuje suchy, męczący kaszel wraz z odruchami wymiotnymi przy jego nasilaniu. Udokumentowano temperaturę ciała dziecka w wysokości 39,0°C. Chłopiec jest niespokojny, zaobserwowano niechęć do przyjmowania posiłków. Pacjent oraz jego opiekunowie wykazują ogólny niepokój związany z koniecznością hospitalizacji. Rodzice chłopca wykazują deficyt wiedzy na temat zakażeń układu oddechowego i profilaktyki nawrotów choroby.

Wnioski. Problemy pielęgnacyjne dziecka ze zdiagnozowanym obturacyjnym zapaleniem oskrzeli wymagają obecności i opieki całego zespołu terapeutycznego, ponieważ występująca duszność stanowi zagrożenie dla życia dziecka. Problemy stwierdzone u pacjenta to: zaburzenia oddychania z powodu utrzymującej się duszności, nieefektywne odkrztuszanie zalegającej wydzieliny oskrzelowej, ryzyko odwodnienia na skutek podwyższonej temperatury ciała, ryzyko utraty masy ciała z powodu niechęci do przyjmowania pokarmów, ryzyko infekcji, jak również potrzeba kompleksowej edukacji rodziców dziecka na temat choroby i profilaktyki.
STRATEGI KOMUNIKASI PEMASARAN DALAM MEMPROMOSIKAN OBJEK WISATA PUNTHUK SETUMBU
Authors: Zulaefa Eva , Suranto Suranto
Published: March 2024

Penelitian ini bertujuan untuk mendiskripsikan: 1) strategi komunikasi pemasaran yang dilakukan oleh Badan Pengelola Wisata Alam dan Sunrise Punthuk Setumbu dalam mempromosikan objek wisata Punthuk Setumbu; 2)  media yang digunakan untuk mempromosikan objek wisata Punthuk Setumbu. Penelitian ini menggunakan metode penelitian dengan pendekatan kualitatif. Penelitian ini dilaksanakan di objek wisata Punthuk Setumbu, Kabupaten Magelang. Informan penelitian adalah bagian pemasaran, ketua pengelola dan pengunjung objek wisata Punthuk Setumbu. Pengumpulan data dilakukan dengan wawancara, observasi dan dokumentasi. Analisis data dilakukan melalui pengumpulan data, reduksi data, sajian data dan penarikan kesimpulan. Pemeriksaan keabsahan data dilakukan dengan triangulasi sumber. Hasil penelitian menunjukkan: 1) pengelola objek wisata Punthuk Setumbu dalam melakukan kegiatan komunikasi pemasaran, menggunakan strategi yaitu a) khalayak sasaran objek wisata Punthuk Setumbu yaitu wisatawan nusantara dengan segmen fotografer dan wisatawan usia 16-30 tahun b) tujuan yang ingin dicapai yaitu meningkatkan kunjungan wisatawan, membangun brand awaraness dan meningkatkan pendapatan, c) pesan yang disampaikan melalui media cetak yaitu berupa informasi fasilitas dan foto-foto, sedangkan media sosial dengan mengajak wisatawan tag foto ke akun instagram Punthuk Setumbu d) saluran personal berupa pameran dan promosi langsung ke tour guide dan driver,sedangkan saluran non personal melalui media cetak dan media elektronik e) anggaran promosi ditetapkan dengan metode tujuan dan tugas, f) bauran promosi yang digunakan yaitu periklanan, promosi penjualan, acara pengalaman, humas publisitas, pemasaran langsung, pemasaran dari mulut ke mulut dan penjualan personal, g) mengukur hasil promosi dilakukan dengan melihat data kunjungan wisatawan, h) dalam mengkoordinasi proses komunikasi yang terintegrasi, semua dilakukan oleh bagian pemasaran. 2) media yang digunakan untuk mempromosikan objek wisata Punthuk Setumbu adalah media cetak, media elektronik dan media sosial.Kata Kunci: Strategi Komunikasi Pemasaran, Promosi Pariwisata, Punthuk Setumbu
Mengembangkan potensi diri untuk remaja introvert melalui konten kreasi Youtube
Authors: Irghansyah Rajiv , Aulia Fernanda Putri , Sabri Sabri
Published: March 2024

Abstrak            Introvert adalah salah satu tipe kepribadian yang lebih fokus pada pikiran, suasana hati,dan perasaan secara internal. Tipe introvert lebih cenderung menyukai waktu bersama satu atau dua orang.Penyebab introvert seperti aspek kepribadian sebagai kombinasi dari dua faktor utama yakni gen an lingkungan. Remaja introvert dapat mengembangkan potensi mereka melalui Youtube. Di Youtube mereka dapat membuat video sekreatif mungkin sehingga mereka dapat menarik banyak pemirsa dan menjadi lebih terkenal. Tujuan penelitian ini agar dapat memotivasi remaja introvert untuk mengembangkan potensi dirinya melalui konten Youtube dan mereka mendapat relasi yang lebih luas. Pada penelitian ini menggunakan metode penelitian kualitatif dengan jenis penelitian deskriptif, dimana pemecahan masalah yang diselidiki dengan menggambarkan  subjek  atau  objek  dapat  berupa  orang, lembaga, masyarakat, dan lainnya yang berdasarkan fakta-fakta. Manfaat dari penelitian ini agar memperluas wawasan bagi orang introvert tentang media sosial Youtube, yang memudahkan remaja introvert dalam mengembangkan potensi diri.Kata kunci : Potensi diri, Remaja, Youtube, Komunikasi. Abstract            Introvert is a personality type that is more focused on thoughts, moods, and feelings internally. Introverts tend to prefer time with one or two people. The causes of introverts are like aspects of personality as a combination of two main factors, namely genes and the environment. Introverted youth can develop their potential through Youtube. On Youtube they can make videos as creative as possible so they can attract a lot of viewers and become more famous. The purpose of this research is to motivate introverted youth to develop their potential through Youtube content and they get wider relationships. In this study, a qualitative research method was used with a descriptive research type, in which the problem solving investigated by describing the subject or object could be in the form of people, institutions, communities, and others based on facts. The benefit of this research is to broaden insight for introverts about Youtube social media, which makes it easier for introverted youth to develop their own potential.Keywords :  Self potential, Youth, Youtube, Communication
Investigating the need for achievement among junior high school students
Authors: Da Costa Augusto , Rachmawati Indriyana , Laksana Eko Pramudya
Published: March 2024

Need for achievement is the encouragement, both within and outside the individual, to perform certain behaviors. This encouragement is needed by individuals to achieve academic achievement in school. The purpose of this study was to determine the percentage of motivation for achieving adolescents in Malang, Indonesia. The research method used is quantitative with a descriptive type of research. The population of this study was 7183 junior high school students. The study led 315 students and sampled using proportional stratified random sampling. The data collection technique uses an achievement motivation scale developed by the researcher himself based on theory and data analysis using frequency in descriptive statistics. The results showed that 69% of adolescents were motivated to perform at a moderate level, 21% at a high level, and 10% at a low level.  This means that the level of motivation for achieving students at a moderate level needs to be improved through the support of parents and teachers, so that students can achieve the expected academic success.
The effect of learning interest and self-efficacy on junior high school students' learning achievement
Authors: Abdi Sofyan , Rahmania Dina
Published: March 2024

This study aims to determine the effect of learning interest and self-efficacy on learning achievement. The population used is all students of class IX, with a sampling technique using random sampling of 72 students. The data collection technique used was a questionnaire and then analyzed with descriptive statistics. The results of this study indicate that there is an effect of interest in learning on learning achievement based on the partial test of 5.067 2.291 with a significant 0.000 0.05, it can be said to be significant, there is also an effect of self-efficacy on learning achievement, with the test results showing a partial test of 3.659 2.291 with a significant 0.000 0.05, it can be said that it is also significant, then interest in learning and efficacy also have a significant effect simultaneously (together) on student achievement of 51,489 3.127. The value of R Square is 0.599 or 59.9% and the remaining 0.41 or 40.1% is influenced by other variables outside the variables of interest in learning and self-efficacy. Such as learning motivation, learning facilities, teacher communication skills, family environment, and students' emotional intelligence.
The effect of permissive parenting style and peer pressure on disruptive behavior: An explanatory study
Authors: Muhliawati Yeni , Purwadi Purwadi
Published: March 2024

This research aims to examine the influence of permissive parenting style and peer pressure on disruptive behavior of students at Muhammadiyah 2 Yogyakarta junior high school The research method used is a quantitative-correlational method with a prediction design. The population of this research is 498 students who were registered as 7th and 8th graders in the 2021/2022 academic year. The research subjects consist of 74 students, selected using purposive sampling technique, with the criteria that they perceive their parents as permissive and have been identified to have a tendency towards disruptive behavior. The measuring instruments used consist of the disruptive behavior scale, the permissive parenting style scale, and the peer pressure scale. The analysis technique used is multiple regression. The findings of this study indicate that there is a significant simultaneous effect of permissive parenting style and peer pressure on disruptive behavior. The effective contribution produced is 42%. Permissive parenting style partially does not have an influence on disruptive behavior, while peer pressure significantly affects the occurrence of disruptive behavior. The school is recommended to increase its awareness of peer pressure that triggers disruptive behavior in students. Parents are expected to adjust their parenting style to minimize the growth of disruptive behavior in children.
Understanding learning anxiety and mental health of final year students: A qualitative study
Authors: Berutu Rohiyati , Mutiawati Mutiawati
Published: March 2024

Anxiety is a feeling of fear, excessive worry, and unpleasant feelings that assume that something bad will happen. Learning anxiety can also be interpreted as a feeling of worry while an individual experience an under pressure situation and inability to complete something. It is normal for students to have excessive anxiety during the learning process, due to the many internal and external factors that occur in their environment. The research method used was descriptive qualitative research. The research instruments used were interviews and observations. The researcher conducted observations at the Universitas Islam Negeri Sumatera Utara and obtained three final year students who experienced excessive learning anxiety, which could disrupt their learning activities. This greatly affects the students’ mental health. Therefore, the researchers aim to examine the impact of excessive learning anxiety on students’ mental health. Among the three students, two students experienced excessive learning anxiety, which had an impact on their physical and mental health. These two students experienced symptoms of shortness of breath and sleep disturbances that interfered with their daily activities. While one student merely had general learning anxiety in the form of fear of something bad happening, which is often experienced by students in general.
Coexistencia de procesos productivos y de conservación en la Amazonía
ecuatoriana
Authors: Sánchez-Capa Maritza , Anguaya Isama Hilda Fabiola
Published: March 2024

La región amazónica de Ecuador está conforma por las provincias
Sucumbíos, Orellana, Napo, Pastaza, Morona Santiago y Zamora Chinchipe, su
extensión es de ~120.000 Km2 1 . En las dos últimas décadas, la educación
superior se ha implementado en cada una de las provincias, buscando
responder a las necesidades de profesionales en los diferentes sectores que
constituyen las actividades económicas principales de cada provincia.
Sucumbíos y Orellana son provincias que sustentan su economía en la
producción petrolera, sin embargo, en esta superficie se encuentran áreas
protegidas como la reserva de la biósfera YASUNÍ, parque nacional Cuyabeno,
reserva Limoncocha, que son áreas con una gran biodiversidad por lo que la
coexistencia entre conservación y producción industrial generan una búsqueda
consante de alternativas sustentables y sostenibles 2. Esta editorial
muestra alternativas productivas sustentables que involucra los recursos y
biodiversidad propios de la región. Este número especial comprenden la
publicación de veinte artículos de investigación originales que abordan el
uso de los recursos, mejoras en la producción agrícola y uso de tecnologías
innovadoras, buscan responder a la necesidad de difundir los trabajos de
investigación de los actores locales, nacionales e internacionales para la
generación de articulación interinstitucional en pro del desarrollo de la
Amazonía ecuatoriana. Estos trabajos fueron presentados en el II Congreso
Internacional de Innovación, Ciencia y Tecnología “AMAZONIA VIVA” (CIICTAV)
3 .
The Role of Placer Deposits in Ensuring the Reproduction of the Mineral Resource Base of Scarce Types of Strategic Mineral Raw Materials in Russia at the Present Stage
Authors: Bortnikov N. , Volkov A. , Lalomov A. , Bochneva A. , Ivanova Yu. , Lalomov D.
Published: March 2024

Placer deposits had (and for a number of components still have) an important role in providing strategic types of mineral resource base for both Russia and the world as a whole. Placers have a number of advantages that make them in demand by the mining industry: relatively shallow (often accessible for open-pit mining) occurrence, disintegrated state of productive deposits, simplicity of enrichment processes (mainly gravitational systems), as well as the possibility of rapid involvement in exploitation, which significantly reduces payback period for investments. All this is even more relevant for modern Russia, when, in the shortest possible time, in conditions of a shortage of credit resources, it is necessary to implement a program of import substitution and provide the country with scarce types of strategic mineral raw materials, such as gold, platinum group metals, tin, rare metals, titanium, chromium, diamonds.
Analysis of the Influence of Systemic Arterial Hypertension and Heart Failure on the Adversement of the Clinical Condition of Patients with Chronic Kidney Disease: A Literature Review
Authors: Franco Amanda Lima , Saggin Rafaela Vieira , Campos Luiza Bastos , Gomes Wendell Christian Cavalcante , Favacho André Angelo Tavares , Silva Renan Willian Costa , Farias Brendo Silva Gaia , Toledo Ana Maria Ferreira Cruz
Published: March 2024

Introduction: systemic arterial hypertension (SAH) and heart failure, epidemiologically, are diseases that model consequences for other systems of the human body, for example chronic kidney disease (CKD). The development of this appears to be a social consequence of lack of knowledge, as its secondary outcomes are controllable and treatable. Countries like Brazil have exorbitant expenses when it comes to financing dialysis and transplant procedures, with an increase in these numbers, especially in young patients decompensated for their underlying diseases. The objective of this work is to observe the incidence in the literature of SAH and heart failure in patients related to the worsening of CKD. Methodology: descriptive study in narrative review, which seeks to answer the PICO acromion “What is the influence of systemic arterial hypertension and heart failure on the worsening of the clinical condition of patients with chronic kidney disease?”. Discussion: CKD's pathophysiology is the loss of kidney function, where they lose functionality and destroy their specific cells, resulting in the inability to maintain metabolic balance. It proves to be a problem of public responsibility, where more and more deaths in the population are reported. The main risk factors for CKD are highly prevalent chronic diseases such as hypertension and heart failure, the first being the most described in the literature as a triggering factor. Thus resulting in worsening of renal function laboratory results, resulting in chronic kidney injury (CRF). Results: Analyzing the databases, articles in the last 10 years were observed, where 38.6% had the descriptors systemic arterial hypertension and heart failure, describing them as their main secondary outcome. Conclusion: to the scientific society, it contributes summarized and updated indexes reporting the relationship between these precursor pathologies. To society, it informs the problem and a way to inform the patient about their health condition and better understanding.
SETSAFE | SETFUSE: 24 ГОДА РАЗРАБОТКИ И ПРОИЗВОДСТВА КОМПОНЕНТОВ ЗАЩИТЫ ЭЛЕКТРИЧЕСКИХ ЦЕПЕЙ
Authors: Трубачёв Б.
Published: March 2024

ООО «Конкур электрик», один из ведущих дистрибьюторов
электромеханических и электронных компонентов в России и СНГ,
представляет компанию Xiamen SET Electronics (SETsafe | SETfuse),
специализирующуюся на разработке и производстве компонентов
защиты электрических цепей. Продукция под брендом SETsafe | SETfuse
поставляется в десятки стран мира и широко используется в различных
сферах, включая телекоммуникации, новую энергетику, источники
питания, хранение энергии, системы освещения, бытовую технику,
мобильное и медицинское оборудование, промышленную автоматику
и др. Компания имеет 24-летнюю историю инноваций и защитила
множество патентов; продукты компании сертифицированы по VDE,
TUV, PSE, KC, UL, cUL, cULus, CCC, CQC, соответствуют протоколам RoHS
и REACH.
Artificial Intelligence
Authors: Tarekar Sagar
Published: March 2024

Abstract: We have chosen this topic to spotlight on one of the most technological trend these days known as AI(Artificial Intelligent). Specific applications of AI include expert systems, natural language processing, speech recognition and machine vision. AI brings up images of high- functioning, human-like robots taking over the world, AI isn’t intended to replace humans. Therefore we will discuss some of the most important aspects related to AI in which it will help in a better understanding of Artificial Intelligent and both its advantages and disadvantages to be able to protect ourselves from the upcoming technological trend.
animação japonesa e a sua marca de distinção no Ocidente
Authors: França Gustavo de Melo
Published: March 2024

Este artigo aborda o modo como a animação japonesa adquiriu uma marca distintiva no Ocidente a partir de toda uma construção histórica. Assim, é discutido como a compreensão sobre a animação japonesa no Ocidente foi influenciada pelas imagens construídas e propagadas a partir de uma visão limitadora e orientalista preexistente acerca do Japão, uma vez que construções estereotipadas podem interpelar o modo como as populações de diferentes localidades interpretaram as produções desse país. Em seguida, é delineada a trajetória da recepção e da distribuição da animação japonesa em contextos ocidentais, utilizando como ponto central de análise os Estados Unidos, que é historicamente o maior consumidor de animação japonesa do bloco ocidental. Com isso, destacamos que o termo “anime” se consolidou no Ocidente como um rótulo que representa uma série de valores agregados relacionados à noção de diferença, mas que, nos últimos anos, com o aumento de animações produzidas fora do Japão que incorporam esquemas estilísticos que durante muito tempo foram relacionados às produções desse país, essa noção estabelecida em torno da animação japonesa está sendo tensionada.