bluuebunny/crossref_metadata_2025 huggingface dataset:
The Organisation of the Education of Returned Emigré Pupils in a Progymnasium
Authors: Žukauskienė Lilia , Zulumskytė Aušrinė , Ozbinaitė Rasa
Published: July 2022

The article focuses on the issue of the education of returned emigré pupils. A progymnasium is part of the Lithuanian system, a general education institution (grades 1 to 8), an intermediate link between primary school and a gymnasium, which differs from basic schools in the higher quality of the activities and the created added value. A quantitative study was conducted: 106 progymnasium teachers working with returned emigré pupils took part. The research revealed that individual plans were made for returned emigré pupils in progymnasiums, and school education specialists (psychologists, social pedagogues, etc) assisted them during the adaptation period. For the teachers working with returned emigré pupils, the competences of recognising their diverse abilities and the management of (information) technology were especially important. Additional formal (Lithuanian language and literature, mathematics) and informal activities, the development of the digitalised content of education, cooperation, and the dissemination of best practices created the preconditions for the streamlining of the education of returned emigré pupils in progymnasiums.
Role of Pelvis and Trunk Biomechanics in Generating Ball Velocity in Baseball Pitching
Authors: Orishimo Karl F. , Kremenic Ian J. , Mullaney Michael J. , Fukunaga Takumi , Serio Nicholas , McHugh Malachy P.
Published: July 2022

Orishimo, KF, Kremenic, IJ, Mullaney, MJ, Fukunaga, T, Serio, N, and McHugh, MP. Role of pelvis and trunk biomechanics in generating ball velocity in baseball pitching. J Strength Cond Res 37(3): 623–628, 2023—The purpose of this study was to determine the impact of pelvis rotation velocity, trunk rotation velocity, and hip-shoulder separation on ball velocity during baseball pitching. Fastball pitching kinematics were recorded in 29 male pitchers (age 17 ± 2 years, 23 high school, 6 college). Pelvis and trunk angular velocities and hip-shoulder separation were calculated and averaged for the 3 fastest pitches. Associations between peak pelvis velocity, peak trunk velocity, hip-shoulder separation at foot contact, and ball velocity were assessed using Pearson correlation coefficients and multiple regression. The average ball velocity was 33.5 ± 2.8 m·s−1. The average hip-shoulder separation at foot contact was 50 ± 12°. The peak pelvis velocity (596 ± 88°·s−1) occurred at 12 ± 11% of the time from stride foot contact to ball release, with the peak trunk velocity (959 ± 120°·s−1) occurring at 36 ± 11%. Peak trunk velocity was predictive of ball velocity (p = 0.002), with 25% of the variability in ball velocity explained. No combination of factors further explained ball velocity. Hip-shoulder separation at foot contact (17%, p = 0.027), peak pelvis velocity (23%, p = 0.008), and the timing of peak pelvis velocity (16%, p = 0.031) individually predicted peak trunk velocity. The combination of peak pelvis velocity, hip-shoulder separation at foot contact, and the timing of peak trunk velocity explained 55% of the variability in trunk rotation velocity (p < 0.001). These data highlight the importance of interactions between pelvis and trunk for maximizing velocity in pitching. Training to improve pelvis-trunk axial dissociation may increase maximal trunk rotation velocity and thereby increase ball velocity without increasing training load on the shoulder and elbow.
Isokinetic Muscle Strength in Elite Soccer Players 3 and 6 months After Anterior Cruciate Ligament Reconstruction
Authors: Milutinović Andreja , Jakovljević Vladimir , Dabović Milinko , Faude Oliver , Radovanović Dragan , Stojanović Emilija
Published: July 2022

Milutinović, A, Jakovljević, V, Dabović, M, Faude, O, Radovanović, D, and Stojanović, E. Isokinetic muscle strength in elite soccer players 3 months and 6 months after anterior cruciate ligament reconstruction. J Strength Cond Res 37(4): e297–e304, 2023—The aim of this study was to evaluate interlimb symmetry in quadriceps and hamstring peak torque of elite soccer players at 3 months (stage 1) and 6 months (stage 2) after anterior cruciate ligament (ACL) reconstruction. Eight male professional soccer players competing at the highest level across different European countries, who had undergone ACL reconstruction, participated in this study. All patients underwent a supervised physiotherapy program after surgery. Data analyses included the use of separate two-way repeated-measures analyses of variance and effect sizes. Although knee extensor and flexor strength of the non-injured limb was found to be relatively unaltered (g = −0.10 to 0.00) between stage 1 and stage 2, comparisons across time points revealed moderate improvements in quadriceps peak torque (p = 0.01, g = 0.52), hamstring peak torque (p = 0.07, g = 0.51), and hamstring:quadriceps (H/Q) ratio (p = 0.03, g = −0.68) of the injured leg, as well as small-large improvements in the quadriceps (p = 0.004, g = 1.24) and hamstring limb symmetry index (LSI) (p = 0.056, g = 0.41). A time-dependent moderate-large asymmetry observed at stage 1 between the injured and noninjured leg in quadriceps peak torque (p < 0.001, g = −1.83), hamstring peak torque (p = 0.157, g = −0.67), and the H:Q ratio (p = 0.06, g = 1.01), as well as between the hamstring and quadriceps LSI (p = 0.03, g = −0.74) was eliminated at stage 2 (g = −0.31 to 0.42). Our findings indicate the importance of supervised and comprehensive therapy, as well as strength screening to assist in recovery aimed at optimizing identified strength deficits following ACL reconstruction.
Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models
Authors: Kaeppler Jakob R , Chen Jianzhou , Buono Mario , Vermeer Jenny , Kannan Pavitra , Cheng Wei‐Chen , Voukantsis Dimitrios , Thompson James M , Hill Mark A , Allen Danny , Gomes Ana , Kersemans Veerle , Kinchesh Paul , Smart Sean , Buffa Francesca , Nerlov Claus , Muschel Ruth J , Markelc Bostjan
Published: July 2022

The effect of radiation therapy on tumor vasculature has long been a subject of debate. Increased oxygenation and perfusion have been documented during radiation therapy. Conversely, apoptosis of endothelial cells in irradiated tumors has been proposed as a major contributor to tumor control. To examine these contradictions, we use multiphoton microscopy in two murine tumor models: MC38, a highly vascularized, and B16F10, a moderately vascularized model, grown in transgenic mice with tdTomato‐labeled endothelium before and after a single (15 Gy) or fractionated (5 × 3 Gy) dose of radiation. Unexpectedly, even these high doses lead to little structural change of the perfused vasculature. Conversely, non‐perfused vessels and blind ends are substantially impaired after radiation accompanied by apoptosis and reduced proliferation of their endothelium. RNAseq analysis of tumor endothelial cells confirms the modification of gene expression in apoptotic and cell cycle regulation pathways after irradiation. Therefore, we conclude that apoptosis of tumor endothelial cells after radiation does not impair vascular structure.
Female reproductive dysfunctions and the gut microbiota
Authors: Chadchan Sangappa B , Singh Vertika , Kommagani Ramakrishna
Published: July 2022

The gut microbiome is considered an endocrine organ that can influence distant organs and associated biological pathways. Recent advances suggest that gut microbial homeostasis is essential for reproductive health and that perturbations in the gut microbiota can lead to reproductive pathologies. This review provides an updated overview of the relationship between the gut microbiome and female reproductive diseases. Specifically, we highlight the most recent findings on the gut microbiome in gynecological pathologies including polycystic ovarian syndrome, endometriosis, and endometrial cancer. Most studies revealed associations between altered gut microbial compositions and these reproductive diseases, though few have suggested cause–effect relationships. Future studies should focus on determining the molecular mechanisms underlying associations between gut microbiota and reproductive diseases. Understanding this bidirectional relationship could lead to the development of novel and effective strategies to prevent, diagnose, and treat female reproductive organ-related diseases.
Sirtuins as potential therapeutic targets for mitigating OxInflammation in typical Rett syndrome: plausible mechanisms and evidence
Authors: Cordone Valeria , Pecorelli Alessandra , Valacchi Giuseppe
Published: July 2022

Graphical abstract

Rett syndrome (RTT), a monogenic neurodevelopmental disorder mainly affecting female, is caused by mutations in X-linked MECP2 gene, an ubiquitous epigenetic regulator. In addition to neurological issues, RTT patients show a variety of multisystem manifestations and impairment of different signalling and metabolic pathways, including compromised mitochondrial function, altered redox homeostasis, improper cholesterol metabolism and subclinical inflammation. The sirtuin family (SIRTs), comprising seven members, catalyses the NAD+-dependent deacetylation, ADP-ribosylation and deacylation of a wide range of targets and works as sensors of cellular energetic status. In addition, SIRTs can modulate activities and gene expression of proteins involved in cellular stress responses related to oxidative stress, mitochondrial dysfunctions and inflammation, in both physiological and pathological conditions. Given some shared molecular aspects, herein, we revised the current scientific literature and hypothesized the possible relationship of SIRTs signalling involvement in RTT pathogenesis and OxInflammation. Although further research is needed, uncovering the possible involvement of SIRTs in RTT could reveal new potential pharmacological targets for the disorder. In light of this, SIRT-enhancing compounds could likely represent a new option to be tested as co-adjuvant alternatives to the current therapies.
Oxidative stress leads to severe phenotypes in sepsis through activation of NLRP3-pyroptosis
Authors: Beltrán-García Jesús , Osca-Verdegal Rebeca , García-Giménez José Luis , Pallardó Federico V.
Published: July 2022

Oxidative stress is an important contributor to sepsis and one of the most important causes of death in intensive care units. Even though sepsis pathogenesis remains obscure due to its heterogenicity and complexity, there is increasing evidence that oxidants and antioxidants play a key role in its onset and progression. Recent evidence suggests that pyroptosis is required for defense against bacterial infection, and it is active in several cell types during sepsis. One of the most relevant mediators of pyroptosis is the NLRP3 inflammasome, and the oxidative stress/NLRP3 signaling pathway is one of the main upstream signals involved in its activation. So, it is of special relevance to clarify how oxidative stress and antioxidants can modulate pyroptosis signals and therefore decrease the deleterious effects that both oxidative stress and pyroptosis-related cytokines can induce in the tissues during sepsis. Recent studies evaluating several antioxidants are promising, but further trials are needed to confirm their potential role as agents to block NLRP3 and mitigate the exacerbated inflammasome-related responses during sepsis.
Essential trace element selenium and redox regulation: its metabolism, physiological function, and related diseases
Authors: Saito Yoshiro
Published: July 2022

Graphical abstract

The essential trace element selenium plays a significant role in redox homeostasis in the human body. Selenium is very reactive and has a potent toxicity; however, the living body cleverly utilizes its reactivity for redox reactions. The biological function of selenium is mainly mediated by selenoproteins, which contain selenocysteine, a cysteine analogue that possesses selenium instead of sulphur. Twenty-five types of human selenoproteins have been identified, including glutathione peroxidase (GPX; for the reduction of hydrogen peroxide and lipid hydroperoxide) and thioredoxin reductase (for redox regulation). Selenoprotein P (SELENOP), which is a major selenoprotein in the plasma, is mainly synthesized in the liver and secreted into the plasma. As a multifunctional protein with selenium-transporting activity, GPX-like activity, and metal-binding properties, SELENOP plays a vital role in selenium metabolism and redox regulation. This review focuses on the relationship between selenium metabolism and redox regulation, particularly on the physiological role of selenoproteins and the pathophysiological implications of its disorder. Furthermore, the significant roles of selenium in infectious diseases and its utility for phylaxis are discussed.
El fenómeno del feminicidio: una revisión sistemática
Authors: Ochoipoma Guerrero Jonathan Harry , Carpio Soto Néstor Neptali , Meza Ninanya William Edgar , Riveros Gerónimo Marquiños Santos
Published: July 2022

The main objectives of this article are to determine the definition of femicide and identify its causes and types. For this, a systematic investigation was carried out where 164 articles were found, of which 123 were disregarded because they did not meet the inclusion criteria, and 41 articles were selected: 26 from Scopus and 15 from Scielo. The data was processed through Microsoft Excel software. As a result of this, the main results obtained were: 81.82% of the selected articles used the murder of women as a frequent term, 33.33% determined that the most frequent cause of femicide is jealousy and 100% of the selected articles identified that the most frequent type of femicide is intimacy. For this reason, it is concluded that there are similar elements in the concepts of femicide analyzed, jealousy is the most frequent cause of femicide and the intimacy and non-intimacy types predominate in the selected articles.
Features of blade shape variation in the aerodynamic improvement of aircraft gas-turbine engine compressors
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Kvasha Yu.A. , Zinevych N.A. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Petrushenko N.V. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine
Published: July 2022

This work is devoted to the development of procedures for the aerodynamic improvement of gas-turbine engine axial-flow compressor blade rows. The aim of the work is to compare the efficiency of two methods for impeller blade shape variation in the aerodynamic improvement of an aircraft gas-turbine engine two-stage fan. The first method consists only in varying the blade profile angle along the blade height, while the second consists in varying the blade profile angle and geometrical parameters. The features of the approach used in the solution of this problem are as follows: formulating quality criteria as the mean integral values of the power characteristics of each impeller of the fan over the operating range of the air flow rate through the impeller and searching for advisable values of the impeller blade parameters by scanning the independent variable range at points that form a uniformly distributed sequence of small length. The basic tool is a numerical method developed at the Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, which simulates 3D turbulent gas flows in the compressor stage blade channels using the complete averaged Navier¬–Stokes equations. The results of multiparameter calculations of 3D turbulent gas flows show that at the initial stage of the aerodynamic improvement of compressor blade rows varying the blade profile angle alone is more efficient; however, increasing the number of elements of the uniformly distributed sequence of points in the variable range increases the possibility of finding a point at which the blade profile aerodynamic characteristics significantly improve. The results obtained are expected to be used in the aerodynamic improvement of gas-turbine engine compressor blade rows.
Comparison of Outcomes of Hemodialysis Adequacy with Dialysate Flow Rate of 500 ml/minute and 650 ml/minute
Authors: Ginting Leo , Permatasari Anggraini , Yasmine Elizsabeth , Koerniawan Dheni
Published: July 2022

Background. The average achievement of hemodialysis adequacy which was carried out twice a week for 4 hours at Fatmawati Hospital was 1.49. As many as 82% had not reached adequate dialysis (Kt/V<1.8). Based on the calculation of the dialysate proportioning system, hemodialysis for 4 hours with a dialysate flow rate/Quick Dialysate Flow (QD) of 500 ml/minute will leave dialysate. In the 1 month observation, there were 1.755.6 liters residual dialysate parts Acid (A) and 6,283.2 liters parts Bicarbonate (B). This residual puts a burden on the hospital in treating liquid waste. But with QD 650 ml/minute, both part A and part B, dialysate is still sufficient. On the other hand, QD can affect the achievement of HD compliance.Aim. Knowing the difference in hemodialysis adequacy with QD 500 ml/minute and 650 ml / minute.Method. This study used a case-control analysis for the control group (QD 500 ml/minute) and the intervention group (QD 650 ml/minute) with a Quasy Experiment design through a comparative analysis approach with matching/cross over techniques. Hemodialysis adequacy (Kt/V) is measured 2 times using the QX calculate application (Daugirdas formula), namely at QD 500 ml/minute and QD 650 ml/minute for further analysis using the Wilcoxon Signed Rank test.Result. The study was conducted on 115 respondents with a total of 230 HD sessions. The mean Kt/V in the intervention group was 1.69 and in the control group 1.49 (p-value = 0.006) and it was seen that there was a shift in the achievement of HD adequacy to a better category; The very inadequate and inadequate adequacy category decreased from QD 500 ml/minute to QD 650 ml/minute, and conversely, the adequate and very adequate adequate category experienced an increase in number.Conclusion. Hemodialysis with QD 650 ml/minute resulted in better hemodialysis adequacy than QD 500 ml/minute.
Covid-19 Case with Mild Pneumonia
Authors: Ikhsan Mukhtar
Published: July 2022

Background: On December 31, 2019, WHO China Country Office reported a case of pneumonia of unknown etiology in Wuhan City, China. On January 7, 2020, China identified pneumonia of unknown etiology as a grew type of coronavirus (coronavirus disease, COVID-19).Case report: A 39-year-old woman – health care worker - came to the hospital with the chief complaint of coughing three days earlier. Dry cough with no phlegm, fever and no shortness of breath. There are also no other complaints. On physical examination found no abnormalities. There is no history of traveling abroad but there is a history of contact with sufferers of COVID-19 when treating patients. Patients diagnosed as acute respiratory infection were given cefixim 2 x 200 mg for 5 days, paracetamol if necessary and vitamins. Chest X-ray examination is normal while CT X-ray examination without contrast shows a picture of ground glass opacity (GGO). The PCR swab was found to be positive. The patient was diagnosed as positive for COVID-9 with Mild Pneumonia. The patient underwent independent isolation by taking the hydrochloroquin sulfate on day 1: 2 x 2 tab, days 2 - 14: 2 x 1 tab. In addition, the patient also took 1 x 1000 mg of Vitamin C supplements, 1 x 200 IU of vitamin D3 and 1 x 20 mg of Zinc.Results:Clinical symptoms are getting better. On the chest CT scan, the GGO image has improved. The PCR swab turned negative. The patient with COVID-19 with Mild Pneumonia cured.
The Association of Race, Ethnicity, and Poverty With Child Maltreatment Reporting
Authors: Rebbe Rebecca , Sattler Kierra MP , Mienko Joseph A.
Published: July 2022

OBJECTIVES

To determine the role of race/ethnicity and poverty in the likelihood of children younger than age 3 years hospitalized because of child abuse and neglect-related injuries being reported to child protective services (CPS) and being assigned a specific maltreatment diagnostic code.

METHODS

We used population-based linked administrative data comprising of birth, hospitalization, and CPS records. Children were identified for maltreatment-related hospitalizations using standardized diagnostic codes. Regression models were used to compute crude and adjusted race/ethnicity estimates regarding the likelihood of being reported to CPS and assigned a specific maltreatment diagnostic code during the maltreatment-related hospitalization.

RESULTS

Of the 3907 children hospitalized because of child maltreatment, those with public health insurance were more likely than those with private insurance (relative risk [RR]: 1.29; 95% confidence interval [CI], 1.16-1.42) and those with Asian/Pacific Islander mothers were less likely than those with White mothers to be reported to CPS (RR: 0.78; 95% CI, 0.65-0.93). No differences were found for children with Black, Hispanic, and Native American mothers compared with those with White mothers for CPS reporting. However, children with Native American mothers (RR: 1.45; 95% CI, 1.11-1.90) and public health insurance (RR: 2.00; 95% CI, 1.63-2.45) were more likely to have a specific maltreatment diagnostic code, the second strongest predictor of a CPS report.

CONCLUSIONS

Race/ethnicity and poverty were factors for CPS reports during a child maltreatment-related hospitalization. It is necessary to implement programs and policies that mitigate implicit bias to prevent inequities in which children receive protective intervention.
Debates críticos y artísticos (1970-1973). Hacia un arte para el socialismo.
Authors: Cofré Cubillos Claudia
Published: July 2022

Durante la Unidad Popular en Chile se gestó una transformación global de la sociedad, que tenía un componente cultural importante, dado que se planteaba incluir la acción cultural como un medio para la superación del “subdesarrollo” y la dependencia. En este contexto se materializan una serie de exposiciones, intercambios y redes entre artistas latinoamericanos, así como importantes debates sobre la condición del arte y la actitud del artista dentro de la sociedad de la época. Se desarrolla, entonces, una cultura de transición al socialismo, influenciada por las condiciones políticas en las que se creó la UP. El presente texto hará un recorrido panorámico por los distintos temas y debates críticos y artísticos que fueron parte del desarrollo cultural de la UP, y que pretendían ofrecer tanto un diagnóstico como un mapa crítico del quehacer de los artistas en un contexto revolucionario de transición al socialismo. Pretendemos así, contribuir mínimamente al rescate de nuestra historia artística y cultural.
Risk factors of gastrointestinal food allergy in young children
Authors:   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Horianska M.H.
Published: July 2022

Purpose - to study risk factors of gastrointestinal food allergy (GIFA) in young children. Materials and methods. 68 young children with GIFA and 22 children of the same age with an unencumbered individual allergy history were examined. A study of children perinatal, family and individual allergy history was conducted, and a survey was conducted on the state of parents’ health. The vitamin D supply of children was determined by quantifying of serum 25-hydroxycalciferol (25(OH)D) concentration by using an immunochemical analyzer. Results. Anamnestic risk factors that showed a significant association with the development of GIFA in young children and reliably differed from the control group were: complicated obstetric history, medical treatment of mothers during pregnancy, early artificial feeding, burdensome family allergy history and gastrointestinal diseases presence in parents. Insufficient supply of vitamin D was in 79.4% of patients with GIFA compared with 13.6% of children in the control group. The average serum 25(OH)D value in children with GIFA was 34.18±1.7 ng/ml, which is significantly lower than in the control group (40.2±2.3 ng/ml; p<0,05), which may be an additional factor in the development and severity of the disease. Conclusions. Risk factors of gastrointestinal food allergy have been identified, which will improve the prevention, early diagnosis and treatment of gastrointestinal allergic disease. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the author. Key words: gastrointestinal food allergy, risk factor, vitamin D, young children.
Serum cystatin C as a marker of renal dysfunction in children with juvenile idiopathic arthritis
Authors:   Dnipro State Medical University, Ukraine, Samsonenko S.V. , Borуsova T.P. ,   Dnipro State Medical University, Ukraine
Published: July 2022

An accurate assessment of the estimated glomerular filtration rate (eGFR) is important for early detection of chronic kidney disease, control of nephrotoxicity, and dose adjustment of drugs. To date, there has been only one cohort retrospective study of the prevalence of chronic kidney disease in children with juvenile idiopathic arthritis (JIA). Purpose - to determine the level of serum cystatin C and, on its basis, the state of eGFR depending on the form of the clinical course, degree of activity, methods of treatment of JIA in children. Materials and methods. 80 children with JIA were examined. The content of serum cystatin C was determined by enzyme-linked immunosorbent assay. The Hoek formula was used to calculate eGFR based on the level of cystatin C in blood serum. Results. A decrease in eGFR below 90 ml/min/1.73m2 to 63.08 ml/min/1.73m2 based on serum cystatin C was found in 41.3% of children with JIA. The variant of the clinical course of JIA does not affect the concentration of serum cystatin С and the level of eGFR. Meanwhile, a high degree of risk of developing a decrease in eGFR in children with polyarthritis was established - 72.7% versus 48.9% (OR=2.78; CI: 1.07-7.24; p<0.04). Elevated serum cystatin С levels and decreased eGFR are associated with the degree of JIA activity and its duration. A decrease in eGFR is observed in all children with high activity of JIA, 71.4% - with low activity, 28.3% - in remission. A low risk of developing a decrease in eGFR in children in remission of JIA was established - 51.5% versus 91.5% (OR=0.10; CI: 0.03-0.34; p<0.001). The duration of the active stage of JIA ≥4 years negatively affects the level of eGFR, which leads to a high risk of developing a decrease in eGFR - 39.4% versus 17% (OR=3.17; CI: 1.13-8.9; p<0.04). A high risk of developing a decrease in eGFR was established in children with JIA who received non-steroidal anti-inflammatory drugs (NSAIDs) at the time of the examination - 54.5% versus 8.5% (OR=12.9; CI: 3.76-44.25; p<0.001). The use of immunobiological therapy is associated with a low risk of developing a decrease in eGFR - 9.1% versus 46.8% (OR=0.11; CI: 0.03-0.42; p<0.001). Conclusions. Renal dysfunction was found in 41.3% of children with JIA. Its development is affected by high activity of JIA, duration of the active stage of JIA ≥4 years, and treatment with NSAIDs. The study was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the institution specified in the work. Informed consent was obtained from the parents of the children for the research. No conflict of interests was declared by the authors. Key words: juvenile idiopathic arthritis, renal dysfunction.
The biological role of chromium and the impact of changes in its content on the course of obesity and hypertension in children (literature review, own research)
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Marushko Yu.V. , Kostynska N.G. ,   Bogomolets National Medical University, Kyiv, Ukraine, Hyshchak T.V. ,   Bogomolets National Medical University, Kyiv, Ukraine,, Marushko T.V. ,   Shupyk National Healthcare University of Ukraine, Kyiv
Published: July 2022

The study of the role of certain microelements deficiency in the human body has not lost its relevance for decades. One of these microelements is chromium. Given its ability to reduce oxidative stress and chronic inflammation in the human body, much attention is being paid to studying the role of chromium in the treatment of obesity and hypertension. A number of scientists in their studies have shown a positive effect of chromium supplementation in these diseases. However, a large number of unexplored questions remain. In particular, most of the studies are devoted to the study of isolated diseases, while many patients usually have a comorbidity of several diseases. Also, the study of the role of this microelement in children remains without the attention of scientists. Most scientists note the need for further research in this direction. Purpose - to summarize the literature data and the results of our own studies of the biological role of chromium and the impact of changes in its content on the course of obesity and hypertension in children. Results and conclusions. Today, the role of chromium in the treatment and prevention of obesity and hypertension continues to be studied. According to literature sources, with a decrease in the level of chromium in the blood plasma of patients, obesity and hypertension are statistically significantly more often recorded. In systematic reviews chromium supplementation has been shown to reduce body weight and systolic and diastolic blood pressure in patients with obesity and hypertension. As a result of the study, it was found that the level of chromium in the hair of school-age children with hypertension in combination with obesity is statistically significantly (p<0.01) lower than in healthy peers. No conflict of interests was declared by the authors. Key words: chromium, microelements, obesity, hypertension, comorbidity, children.
Call center timespace and working from home
Authors: Nielsen Kristina
Published: July 2022

Ethnographies of Indian call centers highlight the space of the global call center and its separateness from domestic life. This separateness is manifested in a chronotope (depiction of place, time and personhood) which allows for the coordination of sociolinguistic practices between call center workers and their colleagues, both domestic and international. Learning to speak like a ‘professional’ is one reason that many people seek work in call centers. For many call center workers this register is learned on the job from colleagues, trainers and managers. Covid-19, a global pandemic which has forced many industries to take adaptive measures in the face of national lockdowns, has led to many workers suddenly working from home. On May 24th 2020, the Government of India ordered a 21-day nation-wide lockdown, limiting the movement of over a billion people and forcing call center employees to work from home. Drawing from interviews with call center employees impeded by the lockdown, along with an analysis of metalinguistic commentaries from call center trainers before the lockdown, I propose that call center timespace serves the purpose of coordination of sociolinguistic practices and the enregisterment of professional forms of personhood emblematically linked to an array of speech norms including but not limited to pronunciation, grammatical norms and the phrasing structure of customer service interactions. The newly mediatized formulations of workers in a work-from-home environment result in a clash between the chronotopes of home and office.
Linguistic Mitigation in English and Spanish: How Speakers Attenuate Expressions Nydia Flores-Ferrán (2020)
Authors: Fang Ying , Lu Diexi
Published: July 2022

Linguistic Mitigation in English and Spanish: How Speakers Attenuate Expressions Nydia Flores-Ferrán (2020) London: Routledge. New York: Taylor and Francis. Pp. 256 ISBN: 9781138584655 (hbk) ISBN: 9780429505867 (eBook)
Study Abroad. Second Language Acquisition and Interculturality Martin Howard (ed.) (2019)
Authors: Golubeva Irina
Published: July 2022

Study Abroad. Second Language Acquisition and Interculturality Martin Howard (ed.) (2019) Clevedon: Multilingual Matters. Pp. 296 ISBN: 9781788924146 (hbk) ISBN: 9781788924139 (pbk) ISBN: 9781788924153 Ebook(PDF) ISBN: 9781788924160 Ebook(EPUB)
Lithuanian: A Comprehensive Grammar Meilute Ramoniene, Joana Pribušauskaite, Jogile Teresa Ramonaite and Loreta Vilkiene (2020)
Authors: Kamandulytė-Merfeldienė Laura
Published: July 2022

Lithuanian: A Comprehensive Grammar Meilute Ramoniene, Joana Pribušauskaite, Jogile Teresa Ramonaite and Loreta Vilkiene (2020) London: Routledge. New York: Taylor and Francis. Pp. 354 ISBN: 9781138063617 (pbk) ISBN: 9781138063600 (hbk) ISBN: 9781315160900 (eBook)
‘Silence is not always golden’
Authors: Orthaber Sara
Published: July 2022

The past two decades have seen a growing interest in research on call centre discourse from sociolinguistic and pragmatic perspectives. Turn-by-turn micro-analyses of call centre interactions have looked at the complex power relations and face-considerations in dealing with customers’ and agents’ impolite behaviour. Although silence is ubiquitous in dyadic conversations, surprisingly few studies of call centre interactions have investigated silence between adjacency pairs and the potential trouble it may indicate. To fill this gap, this paper explores silence in service calls. Specifically, it first looks at routine calls for information and the most common ways in which silence is accounted for by the agents. It then examines non-routine calls where silence becomes interactionally meaningful following the agents’ withheld responses at a transition-relevance place. Thus, silence becomes marked behaviour by virtue of being oriented to as unexpected by the customer and thus open to evaluations of impoliteness.
I’m sorry, my what?
Authors: Friginal Eric
Published: July 2022

This paper explores caller clarification sequences in outsourced call center interactions, with the goal of categorizing distinguishable causes or reasons for their occurrence, as identified by third-party evaluators – i.e., raters who are not participants in the call. Caller clarifications are questions, requests, or follow-up statements raised by a caller after a call-taker’s turn while providing information or a procedure during call center interactions (Friginal, 2009a). These potentially unnecessary caller clarifications should have been avoidable if both speakers had been able to communicate and process simplified information effectively. Data were collected from a corpus of transactions, with 545 audio files from the same number of unique Filipino call-takers communicating with customers from the U.S. (N = 578, 511 words). Results show that there are 2.051 caller clarifications per 1,000 words in the corpus, based on a total of 1,186 raw instances of caller clarifications. Implications for agent training, the framework of analyzing and categorizing caller clarification, and understanding the nature of intercultural business communication are discussed.
Current trends and the way forward on call center research in a post-covid world
Authors: Tovar Johanna
Published: July 2022

Applying sociolinguistic perspectives, this issue explores the most recent developments in call center research and the impact call center work has on agents. Significant issues are addressed in call center interactions, including web chat, agent stigmatization, agent resistance, agent training and the impact of Covid-19. The essays provide a forum where developments are critically reviewed and future areas of research explored, including how call center work can be improved. The first article by Nielsen addresses the impact of the Covid-19 pandemic in India and working from home through the notions of chronotopes. The second article in the issue by Lockwood develops a framework for the assessment of written web chats in offshore call centers. The third essay by Friginal examines how the voice assessment of Filipino agents can be improved through caller clarification sequences. Tovar’s paper, the fourth paper in this collection, focuses on the strain that working in a call center creates for agents and how they resolve this. The fifth paper by Orthaber examines resistance and passive compliance in call center interactions in a Slovenian call center using turn-by-turn micro-analysis of service conversations with a focus on silences. Despite the different angles, the papers share themes of resistance (creative compliance) and the development of a new register of call center speak, while also highlighting agency among call center workers.
Effect of extraction parameters on the isolation of fenugreek seed protein and characterization of fenugreek protein concentrate
Authors: Kumari Neha , Kumar Pradyuman , Wani Sajad Ahmad
Published: July 2022

The present study was accomplished with the isolation of fenugreek seed protein. Effect of extraction parameters on the isolation of fenugreek seed protein from defatted fenugreek seed powder and characterization of the isolated protein was done. The pH (10, 11, 12, and 13), time (15 and 20 min), and rpm (7500 and 8000) were used to extract fenugreek protein from defatted fenugreek seed powder. The obtained protein was characterized for its functional, structural, morphological, and thermal properties. SEM, XRD, FTIR, and DSC revealed that the protein extracted at pH 12 had better functional, morphological, structural, and thermal properties. Color values indicated the dark color of fenugreek protein at alkaline pH. It was found that the protein extracted at pH 12, time 20 min, and rpm 8000 showed desirable functional, structural, morphological, and thermal properties as compared to others.
Linguistic Characteristics of the Captions to Internet Posts of English-Speaking Influencers
Authors:   Northern (Arctic) Federal University named after M.V. Lomonosov, Kaziaba Viktoria , Barmina Dana ,   Northern (Arctic) Federal University named after M.V. Lomonosov
Published: July 2022

The article is devoted to a multidimensional analysis of the linguistic properties of captions, i.e. texts under publications of English-speaking influencers on the Internet. The research is aimed at studying the syntactic, lexical-and-semantic, thematic and graphic features of the verbal component of opinion leaders' posts on the Internet platform. Interest in the verbal output of this category of communicants is due to their authority compared to other users, as well as due to the commercialization of their communication in the absence of special knowledge and qualifications. The factual material includes 2000 captions, which belong to 100 popular opinion leaders in the English-language Internet segment. At the center of the research methodology there are multidirectional critical content analysis, linguo-statistical and corpus methods of data processing, including automated ones, using application programs for SEO-analytics. The results of the captions study reveal their syntactic design mainly in the form of sentences and small narrative texts. A poor, plain and easy-to-follow vocabulary with a lot of inconsequential words makes the influencers' captions understandable and readable for general consumption. The emotional tone of the captions is ambivalent – neutral to a greater degree, or rather positive. The active usage of graphic means (ideograms, iteration, capitalization) is not creative, but only serves as a visual reinforcement and intensification of the transmitted intentions. The disclosure of the topics covered in the captions is superficially conducted. However, the subject matter is wide and focused on representation of impressionistic experiences and routine events in the author's life. This posting strategy is similar to online-diary genre. It allows influencers to make their virtual presence felt on a daily basis, thus, creating minor news hooks, and to engage their readers emotionally, while broadcasting hidden advertising under the guise of personal preferences, tips and recommendations.
Solving a Class of Two-dimensional Nonlinear Volterra Integral Equations As a Generalized Problem of Moments
Authors: Pintarelli María B.
Published: July 2022

It will be shown that solve an equation two-dimensional Volterra nonlinear can be solved numerically applying the techniques of inverse generalized moments problem in two steps writing the Volterra's equation as a Klein-Gordon equation of the form wtt – wxx
= H(x, t), which H(x, t) it is unknown. In a first step, H(x, t) is numerically approximate, and in a second step we numerically approximate the solution of Klein-Gordon equation using the H(x, t) previously approximated. The method is
illustrated with examples.
Effects of Teaching Geometry Using Mobile App Instructional Technique on Students Interest in Bayelsa State
Authors: Charles–Owaba  , Tekenate  , Doris Omeodu Muvoke
Published: July 2022

The study investigated the effect of teaching geometry using mobile application instructional technique on senior secondary students' interest in Geometry in Bayelsa State. A quasi-experimental, non-equivalent control group design was used in the study. All the 506 SS2 mathematics students
in the three federal unity schools formed the population of the study. One hundred and seventy nine (179) students from two schools formed the sample of the study. Intact classes were assigned by flipping of coin to either experimental or control group; and separately taught by their regular
mathematics teachers who had earlier been trained for the purpose. All the groups were pre and post-tested. Geometry Interest Inventory (GII) was used as instruments for both the control and experimental groups. Three research questions and three hypotheses guided the study. The mean and standard
deviation were used to answer the research questions, while Analysis of Covariance (ANCOVA) was used in testing the hypotheses at .05 levels of significance. The result showed that the use of mobile application instructional technique as a medium of teaching improves students' interest in
geometry. Also there was no significant effect between teaching method, gender and choice of discipline on students' interest in Geometry. The study recommended that the use of mobile application should be integrated into the teaching and learning of mathematics generally.
Análise em pilares de edifícios de múltiplos pavimentos em concreto pré-moldado durante a etapa transitória
Authors: Francisco Otrente João , de Araújo Ferreira Marcelo , Lima Rocha Arthur , Catoia Bruna
Published: July 2022

RESUMO Diferentemente das estruturas moldadas no local, os sistemas pré-moldados de concreto apresentam basicamente como particularidades: projeto das ligações e a consideração de outras situações de cálculo diferentes da final de projeto. Essas situações são as fases da etapa transitória, envolvendo: desmoldagem, armazenamento, transporte e montagem. Nesta etapa, a peça pode apresentar esquemas estáticos e solicitações diferentes, podendo ocasionar uma condição mais crítica em E.L.U ou E.L.S. A exemplo disso, pode-se citar o caso do pilar pré-moldado que durante esta etapa apresenta comportamento de viga devido a sua posição horizontal. Assim, objetivo deste trabalho é realizar um estudo da posição das alças de içamento em um pilar pré-moldado de concreto que apresenta fases transitórias críticas, de modo a buscar uma posição admissível desses vínculos que resulte na melhor distribuição de esforços e controle da fissuração. Para tal, foi realizada uma análise paramétrica durante a fase de desmoldagem e montagem com o elemento dispondo de 2 alças, cujos parâmetros obtidos com a variação da posição das alças foram: momentos fletores, tensão na armadura e coeficiente redutor de rigidez para as seções mais solicitadas. Na sequência, foram obtidos os mesmos parâmetros, todavia empregando 3 alças na ocasião do saque e 3 pontos para o içamento, totalizando 3 posições típicas de esquema estático para essas fases. Os resultados mostraram que ao empregar 3 alças foi possível o controle da fissuração, redução da armadura necessária e da tensão nas mesmas. A análise paramétrica constatou-se que a rigidez do elemento seria superior a 0,50.EI somente com um nível de tensão abaixo de 0,30, mostrando que não necessariamente limitar a tensão na armadura em 0,50.fyk é uma garantia de E.L.S-F admissível, evidenciando ainda que a perda de rigidez em etapa transitória deve ser considerada, pois não basta atender as condições normativas somente em etapa final de projeto.
Complementary therapies in the control of male lower urinary tract symptoms: A systematic review
Authors: Mata Luciana Regina Ferreira da , Motter Paula Giuliana Rodrigues , Azevedo Cissa , Bernardes Mariana Ferreira Vaz Gontijo , Chianca Tânia Couto Machado , Vasques Christiane Inocêncio
Published: July 2022

Abstract Objective: to evaluate diverse scientific evidence on the effectiveness of complementary therapies in the control of lower urinary tract symptoms in the adult and aged male population. Method: a systematic review developed according to the PRISMA checklist. The search was performed in the CINAHL, Embase, LILACS, PEDro, PubMed, Web of Science and Google Scholar databases. Results: a total of 585 records were identified and 12 clinical trials were selected that met the inclusion criteria. The outcomes considered by the studies for analyzing effectiveness of the complementary therapies were validated questionnaires to assess the severity of the lower urinary tract symptoms (sensation of incomplete bladder emptying, frequent urination, intermittent flow, weak flow, pain or difficulty urinating, nocturia and urgency) and urodynamics parameters. The studies analyzed the complementary phytotherapy (n=8) and electroacupuncture (n=4) therapies. Six studies related to phytotherapy showed statistical significance. Electroacupuncture showed a significant improvement in the symptoms in two studies. Conclusion: pytotherapy was effective to control the simptoms related to frequency, urgency, nocturia, incomplete emptying, intermittence, weak flow and effort to initiate urination. To confirm the effectiveness of electroacupuncture, research studies with well-designed methodologies will also be necessary to resolve the divergences between the studies of this review.