bluuebunny/crossref_metadata_2025 huggingface dataset:
Qualitative assessment of algae harmful bloom impact in autumn 2020 off the coast of South-Eastern Kamchatka (North-West Pacific) on shallow-water benthic communities
Authors:   Kamchatka Branch of Pacific Geographical Institute of Far-Eastern Branch of Russian Academy of Sciences, Sanamyan N.P. , Korobok A.V. ,   Kamchatka Department for Hydrometeorology and Environmental Monitoring, Sanamyan K.E. ,   Kamchatka Branch of Pacific Geographical Institute of Far-Eastern Branch of Russian Academy of Sciences
Published: April 2023

The results of monitoring of the benthic communities’ state during two years after the ecological catastrophe caused by an outbreak of planktonic microalgae off the coast of Kamchatka in autumn 2020 were presented. The consequences of this phenomenon led to the mass extinction of bottom organisms. As a result, in the zone of the upper sublittoral, a strong depletion of the benthic fauna occurred, not only many species, but also entire groups of animals fell out of its composition: most of the sponges and about a half of species of sea anemones, mollusks, echinoderms, ascidians have disappeared. However, the quantity of some groups of Crustacea has increased significantly.
Monitoring of the blue crab fishery (Paralithodes platypus Brandt) in the throat of Shelikhov Bay in January 2018
Authors:   Kamchatka Branch of Pacific Geographical Institute of the Far Eastern Branch of the Russian Academy of Sciences, Korostelev S.G.
Published: April 2023

It is stated that January there is the most intensive blue crab fishing period in the Shelikhov Bay during the year. At the same time, the catch of males of commercial size per day was 13.474 tons or 7600 pcs. However, this value does not reflect the real possibility of catching per day, since it is limited to the possibility of raw material processing per day (15–16 tons). Information on the size-weight composition of catches and the biological state of crabs is given, as well as the species composition of the by-catch of other species of fish and invertebrates in trap fishing is analyzed.
A brief overview to give a new perspective on mole drainage
Authors: Muhittin Yağmur Polat , Mehmet Emin Bilgili
Published: April 2023

Draining excess water from the soil is the general purpose of drainage. Thus, soil protection is provided and product losses are prevented. Mole drainage consists of underground galleries that act as piped drainage. This type of drainage is mostly used successfully in clay, organic, and highly cohesive soils. It is used successfully in areas with high groundwater, during the improvement of salty and sodium soils. The biggest benefit of mole drainage is cheap and economical. In the mole drainage method, tunnels are opened under the tillage depth with a torpedo-shaped piece at the end of a foot extending under the soil. These tunnels are called mole drains. In the mole drainage method, the channels are built with mole drain plows and subsoilers. In order to benefit more effectively from mole drainages, parameters such as suitable working width, working depth and slope must be finely adjusted. For this, modern alternatives such as GPS and laser positioning systems can be used.
Updates in management of abdominal sepsis
Authors: Mirla Fontes de Araujo Borges , Roosveni de Sousa Lacerda , Igor de Sousa Oliveira , Sávio Benvindo Ferreira
Published: April 2023

Sepsis is an organ dysfunction caused by a disproportionate host response to infection. The condition is responsible for 1 in every 3 admissions to an intensive care unit (ICU) and about 6 million deaths worldwide. As a result of the imbalance in the inflammatory response, immune dysfunction, mitochondrial damage and other pathophysiological processes, sepsis progresses extremely. This research aimed to search the literature for updates inherent to the therapeutic approach of patients with diseases secondary to intra-abdominal sepsis. The present work is a narrative review with a bibliographical survey carried out in the PUBMED and Virtual Health Library (VHL) research bases, through the search strategy using the following descriptors, in both virtual libraries: “sepsis OR surviving sepsis” AND “intra abdominal infection” AND “therapeutic”. At the end of reading the articles in full, ten papers were selected, from which it was observed that new recommendations regarding volume operative source control, and use of additional therapies therapy. The open abdomen technique is being further explored, as well as more in-depth studies on new drugs for this condition, such as acetylcholinesterase inhibitors, and the use of glucocorticoids became contraindicated, due to low scientific evidence. Therefore, it is concluded that, as it is a medical emergency with high mortality, it is relevant to develop scientific research aimed at the effectiveness, feasibility and safety of new forms of management.
Numerical analysis of forming the tri-layer non-homogeneous bellows via the hydroforming process
Authors: Pezhman Ghanbari , Behnam Akhoundi , Vahid Modanloo
Published: April 2023

Due to the complex and structural characteristics of non-homogeneous layers in hydroforming, their forming is a challenging process. In this research, the manufacturing process of three-layered bellows made of 304 stainless steel (two outer layers) and Inconel 718 (inner layer) is numerically investigated. The effects of different parameters on the forming of bellows are studied. To study the effect of friction between layers, two models are used; a model with friction between layers and a model with tied layers. It is observed that the amount of displacement in the model with a tie connection is more. The maximum values of stresses are detected in the inner region after the second stage of forming, i.e. folding. These values reduce after the spring-back step.
Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain v1
Authors: Lin Yiting
Published: April 2023

Objectives This study aimedto compare the efficacy of online exercise therapy with conventional exercise therapy on pain, function, psychological status and work efficiency of young adults with chronic neck pain. Methods A randomized clinical trial recruiting35 university students with self-reported chronic neck pain was conducted. Participants were randomly assigned into the experimental group receiving online exercise therapy and the active control group receiving conventional exercise therapy.Participants in both groups completed the same exercise program 3sessions per week for 6 weeks, with either face-to-face or online mode of delivery by physiotherapists.The pain level was assessed using visual analogue scale (VAS)based on average and at maximum intensity. Neck function and work limitations were assessed by the Neck Disability Index (NDI) and Work Limitations Questionnaire (WLQ) respectively. The Hospital Anxiety and Depression Scale (HADS) and its sub-scales(HADS-A and HADS-D)were used to evaluate the overall symptoms, levels of anxiety and depression respectively.Participants were assessed at baseline and at 6 weeks while the changes in WLQ were assessed biweekly.
Isolation of bacterial DNA with Gentra Puregene kit (modified protocol) v1
Authors: not provided o.pogoutse
Published: April 2023

The Qiagen protocol for purification of genomic DNA from gram-positive bacterial cultures using Yeast/Bact. Kit ( Gentra Puregene Handbook - QIAGEN) was modified to aid in the isolation of bacterial DNA from heterogeneous, low volume, low OD cultures
Study Population(Part 4 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain") v1
Authors: Lin Yiting
Published: April 2023

This is a Part 4 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain". The target participants were adults with self-reported non-specific neck pain for more than three months.
Study design/methodology (Part 3 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain") v1
Authors: Lin Yiting
Published: April 2023

This is a Part 3 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain". Randomized clinical trial with 39 adults with self-reported chronic neck pain recruited. They were randomly assigned into two groups. The experimental group received online exercise therapy and the control group received conventional exercise therapy.Participants in both groups completed the same exercise program three times a week for six weeks with either face-to-face or online mode of delivery by physiotherapists.The degree of pain was assessed by the improvement in average and maximum VAS. Neck function and work limitations were assessed by NDI and WLQ respectively. HADS and its subscales were used to evaluate anxiety and depressive symptoms.
Interventions (Part 5 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain") v1
Authors: Lin Yiting
Published: April 2023

This is Part 5 "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain". Participants in both groups completed the same exercise program three times a week for six weeks with either face-to-face or online mode of delivery by physiotherapists. The intervention includes: A. Warm-up exercises B. Cranio-cervical flexion exercises C. Strength-endurance exercises D. Scapular stabilization exercises E. Stretching exercises
Objectives (Part 2 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain") v1
Authors: Lin Yiting
Published: April 2023

This is Part 2 of "Effects of Online Exercise Intervention on Physical and Mental Conditions in Young Adults with Chronic Neck Pain". The primary objective is to investigate the effectiveness of online and conventional exercise therapy on pain and function in adults with chronic neck pain. The secondary objective is to investigate the effectiveness of online and conventional exercise therapy on mental condition and working efficacy in adults with chronic neck pain.
Transforming the marine bacterium Ruegeria pomeroyi using tri-parental mating v1
Authors: Gao Cherry
Published: April 2023

This protocol describes a tri-parental mating method for transforming the model marine bacterium Ruegeria pomeroyi DSS-3 with a desired recombinant plasmid. This transformation method is reliable, easy-to-use, and does not require specialized equipment. Using this method, we have successfully transformed R. pomeroyi with large plasmids (up to 14.833 kb) which enabled the construction of the first fluorescent reporter strains of R. pomeroyi (described in doi.org/10.1038/s41467-020-15693-z).
Motivación deportiva, autoestima, autoeficacia y estilo parental en una muestra de adolescentes deportistas profesionales del Inder Envigado, Colombia
Authors: Klimenko Olena , Acevedo Londoño Juan Esteban , Ríos Botero Juan Sebastián , Londoño López John Fredy
Published: April 2023

Este artículo presenta los resultados de un estudio cuantitativo y descriptivo, en el cual se emplearon métodos no experimentales, con el objetivo de describir la motivación deportiva, la autoestima, la autoeficacia y el estilo parental en una muestra de 119 deportistas del Instituto de Deporte, Recreación y Aprovechamiento del Tiempo Libre (Inder Envigado). Se empleó el cuestionario de autoestima de Rosenberg (1965), la escala de autoeficacia de Baessler y Schwarzer (1996), la escala de evaluación del estilo parental de Oliva Delgado et al. (2007) y la escala de motivación deportiva de López (2000). Los resultados indican una correlación positiva entre la autoestima y la motivación intrínseca de autosuperación (r (117) = 0,22, p < 0,05); entre la autoestima y la motivación intrínseca al cumplimiento (r (117) = 0,24, p < 0,05); y entre la autoeficacia y la motivación deportiva general (r (117) = 0,23, p < 0,05). El total del estilo parental se correlacionó positivamente tanto con la motivación intrínseca de autosuperación (r (117) = 0,23, p < 0,05) como con la motivación intrínseca al cumplimiento (r (117) = 0,19, p < 0,05). Se encontró que las características de promoción de autonomía, afecto y comunicación, revelación, y humor tienen una incidencia positiva para la motivación deportiva en los adolescentes.
«The Female Sultanate» in the Ottoman History: Essence, Causes of Emergence, Evolution
Authors:   Taras Shevchenko national University of Kyiv, Samchenko Felix
Published: April 2023

The «Female Sultanate» was an organic component of the history of the Ottoman Empire, being a logical product of its development in the context of strengthening the power of the harem institution together with the persons who belonged to its circle of employees. The figure of the valide-sultan in this system mostly played the role of peculiar unifying center of the new model of power. At this time, the development of many negative trends in the political, personnel and financial components of the Ottoman existence, the growth of corruption and the weakening of administrative power in the person of the grand vizier and other officials. At the same time, the «Female Sultanate» played a certain stabilizing function in state administration and ensuring a single dynasty on the Ottoman throne. His separate important achievement was the initiation by the ruling valide-Sultans of the practice of establishing numerous charitable institutions. In the foreign policy sphere during this period, a diplomatic approach to solving problematic issues began to dominate, which was often based on the personal favor of the ruling sultans. The gradual departure from the harem model of state management was accompanied by numerous upheavals, but it was an objective and necessary process. This was due to the fact that the harem as a management institution had almost completely exhausted itself and could no longer effectively solve the challenges that faced it in the context of overcoming destructive phenomena in the economy and centrifugal tendencies in the provinces. Along with this, it would be incorrect to blame the «Female Sultanate» for the fact that the process of the decline of the Ottoman Empire began because of it, since most of the problems of its development began even before the onset of the specified period, and with its end, on the contrary, only intensified, as they were in the majority a logical product of the peculiarities of the functioning of the state for a long time.
Trafficking in Women and Girls on a Global Level under International Law
Authors: Solntsev A. M. , Popovic M.
Published: April 2023

Human trafficking as a term is often used in everyday life. As a manifestation of organized crime, it is a form of modern slavery and affects all states, both developing and developed, highlighting the seriousness of the problem for the entire international community. Human trafficking is a gross violation of human rights, such as the right to life, freedom of movement, etc. All people can become victims, regardless of gender, age, social status, skin color, but often victims are the most vulnerable groups of the population. In the framework of this study, we will analyze the international legal mechanisms that are designed to counter human trafficking. Women and girls are particularly vulnerable to the challenge of human trafficking, and we will pay special attention to this category in our analysis of legal protection. Protection of human rights is certainly one of the most important aspects of the development of each country. The United Nations treaties on human rights are the foundation of the international system for the promotion and protection of human rights.
Bartolomé Pérez, Nicolás (2022), Derechu Llingüísticu del Pricipáu d’Asturies. Normativa y xurisprudencia, Uviéu: Gobiernu del Principáu d’Asturies
Authors: Galán y González Inaciu
Published: April 2023

Bartolomé Pérez, Nicolás (2022), Derechu Llingüísticu del Pricipáu d’Asturies. Normativa y xurisprudencia, Uviéu: Gobiernu del Principáu d’Asturies
Evaluation of Biocompatibility of New Osteoplastic Xenomaterials Containing Zoledronic Acid and Strontium Ranelate
Authors: Stogov Maksim V. , Dyuryagina Olga V. , Silant'eva Tamara A. , Shipitsyna Irina V. , Kireeva Elena A. , Stepanov Mikhail A.
Published: April 2023

Background. The problem of improving the functional characteristics of implanted devices and materials used in traumatology and orthopedics is a topical issue.
Aim of the study to study biocompatibility of bovine bone matrix xenomaterials modified by zoledronic acid and strontium ranelate when implanted into the bone defect cavity.
Methods. The study was performed on 24 male rabbits of the Soviet Chinchilla breed. Test blocks of bone matrix were implanted into the cavity of bone defects of the femur. Group 1 animals (n = 8, control group) were implanted with bone xenogenic material (Bio-Ost osteoplastic matrix). Group 2 animals (n = 8) were implanted with bone xenogenic material impregnated with zoledronic acid. Group 3 animals (n = 8) were implanted with bone xenogeneic material impregnated with strontium ranelate. Supercritical fluid extraction technology was used to purify the material and impregnate it with zoledronic acid and strontium ranelate. Radiological, pathomorphological, histological and laboratory (hematology and blood biochemistry) diagnostic methods were used to assess biocompatibility. Follow-up period was 182 days after implantation.
Results. It was found out that on the 182nd day after implantation the median area of the newly-formed bone tissue in the defect modeling area in Group 1 was 79%, in Group 2 0%, in Group 3 67%. In Group 2 the maximum area by this period was filled with connective tissue 77%. Median relative area of implanted material fragments in Group 1 was 4%, in Group 2 23%, in Group 3 15%. No infection or material rejection was observed in animals of all groups. There were no signs of intoxication or prolonged systemic inflammatory reaction. Laboratory parameters did not change significantly over time. One animal in each group experienced one-time increase in C-reactive protein level against the background of leukocytosis. Two animals in Group 1 had a slight migration of implanted material under the skin, one animal developed arthritis of the knee joint.
Conclusion. Osteoplastic materials based on bovine bone xenomatrix and filled with zoledronic acid and strontium ranelate have acceptable values of biocompatibility including their safety profile.
The problem of toxoplasmosis in outpatient practice. Part I. Toxoplasmosis in immunocompromised patients
Authors: Vasiliev Valerii V. , Romanova Elena S.
Published: April 2023

Toxoplasmosis remains one of the most common opportunistic infections in immunocompromised patients, primarily in people living with HIV. An increase in the number of requests for medical care by patients with HIV infection as the disease progresses determines the need for knowledge of outpatient therapists and general practitioners of decision-making algorithms for suspected toxoplasmosis in such patients. The main clinical manifestations of toxoplasmosis in patients with immunodeficiency states, the formulation of a preliminary diagnosis, and the routing algorithm are given.
The memory to S.L. Plavinsky
Authors: Kuznetsova Olga Y.
Published: April 2023

The obituary is dedicated to the member of the editorial board of the Russian Family Doctor Journal Professor S.L. Plavinsky.
Patterns of responsible consumption
Authors: Saginova O. V. , Zavyalov D. V. , Zavyalova N. B.
Published: April 2023

Purpose: to identify patterns of responsible consumer behavior within Sustainable Development Goals (SDG 12), recognized and shared by young consumers in Russia.

Methods: the article uses analysis, synthesis, systematization, generalization, analysis of scientific publications and online survey. According to the keywords of scientific publications for 2018-2022, a list of patterns of responsible consumption was selected from the bibliometric systems ScienceDirect and e-library, which were then used for an online survey of 600 young active consumers about their understanding of and attitude to responsible consumption.

Results: the analysis of concepts related to the Sustainable Development Goals, first of all, SDG 12, is carried out: sustainable, ethical, ecological, green, and responsible consumption, anti-consumption, and their interrelationships. The patterns of responsible behavior were identified: economical use of available resources (water, electricity), limitation of the purchased products, participation in products secondary use and sharing, waste disposal, product selection or refusal to use basing on the environmental impact. The most common form of responsible consumption is patterns associated with saving resources and reusing things. The example of other consumers is a more effective incentive than propaganda and information from manufacturers and media. Among the barriers to responsible consumption, economic factors, or the need to make additional efforts are most often mentioned.

Conclusions and Relevance: the main driver of responsible consumption is saving, limiting unnecessary spending. Among the forms of responsible consumption, those associated with saving of resources and limiting the number of purchased goods prevail. Consumers are not ready to pay more for responsible consumption - the increase in costs is the main barrier. Consumers are willing to exercise responsible consumption if this helps reduce costs by consuming fewer resources and make purchases at affordable price.
Import substitution processesin Russian industry: theoretical and practical aspects
Authors: Tyukavkin N. M. , Anisimova V. Yu.
Published: April 2023

Purpose:of the work is to study the main aspects of Russian import substitution in the context of modern political transformations. Methods: the work uses a systematic approach, the induction-deduction method, the method of assessments and scientific abstractions, the method of classification and systematization, the methods of information analysis and synthesis, the statistical method and the method of data visualization.

Results:the author's definition of the term "import substitution" is revealed, which differs from the rest by focusing on the production of innovative and high-tech products both in the domestic and foreign markets with the full support of the state. The problematic issues hindering the development of import substitution processes and reducing the effectiveness of this process in the Russian Federation are identified, which can be overcome and solved if we take into account the world experience of successful import substitution and analyze the indicators of the innovation policy of the Russian economy over the past few years. The key features of import substitution as an economic process are highlighted using statistical information on the share of high-tech products of knowledge-intensive industries in the country's GDP under sanctions. The problems hindering the development and reducing the effectiveness of import substitution processes in the Russian Federation are also disclosed, as well as ways to solve them based on world practice are substantiated. Possible trajectories of the state policy for the development of import substitution have been identified.

Conclusions and Relevance: the essence of import substitution should take into account both socio-economic and political factors, which will allow the state to develop steadily in the economic and industrial spheres. Measures to increase the competitiveness of products produced on the domestic market can be the modernization of the technological base of an industrial enterprise, an increase in its efficiency indicators and an emphasis on the production of goods that can withstand healthy competition and have increased added value. When implementing the import substitution policy, it is necessary to improve the industrial complex of Russia and transition to an innovative type of economic development model.
Particulars of the attenuation parameter determining from real data
Authors: Vasilenko N. K. , Mitrofanov G. M. , Goreyavchev N. A. , Kushnarev R. S.
Published: April 2023

The paper considers the estimation of the attenuation parameter using the method of spectral ratios. Based on model and real data, it is shown that in order to obtain stable estimates, it is necessary to have the most complete information about the structure-velocity characteristics of the medium. Also, an important aspect of data preprocessing is to take into account changes in the waveform associated with the transmission medium.
Agronomic characteristics and yield of corn after inoculation with Bacillus amyloliquefaciens
Authors: Silva Ariana Vieira , de Melo Gonçalves Jaqueline , Costa Natalia , Moreira Scalli Bruno , Cardoso de Oliveira Thiago , Carolina Franqueira de Toledo Sartori Taís
Published: April 2023

Corn is one of the most important crops in Brazil and, due to its physiological characteristics, it has a high productive potential and high nutritional quality, for animal and human nutrition. Therefore, this work sought to evaluate Bacillus amyloliquefaciens subsp. plantarum FZB42 on agronomic characteristics and yield of corn crop. A randomized block design was used, with six doses of B. amyloliquefaciens subsp. Plantarum FZB42 (0.0; 2.5; 5.0; 7.5; 10.0, and 12.5 mL kg-1 seeds) and four repetitions, totaling 24 experimental units. The study was conducted in the experimental area of annual crops of the Instituto Federal de Educação, Ciência e Tecnologia do Sul de Minas Gerais (Federal Institute of Education, Science and Technology of the South of Minas Gerais — IFSULDEMINAS), Muzambinho Campus, in the 2017/18 agricultural year. The agronomic evaluations were: plant height, upper ear insertion height, culm diameter, leaf nitrogen content, forage fresh mass, incidence of Fusarium in the ear, number of rows per ear, number of grains per row, mass of 1000 grains, and yield. The nutritional evaluations performed were: crude protein, ash, ether extract, crude fiber, fiber in acid detergent, and fiber in neutral detergent. In summary, the inoculation of B. amyloliquefaciens subsp. Plantarum FZB42 in corn seeds, regardless of the dose applied, did not interfere with the agronomic characteristics and nutritional quality of corn silage.
Side dressing nitrogen fertilization in soybean in association with inoculation
Authors: Spaziani Pereira Cassiano , Vilela Andrade Fiorini Ivan , BENNEMANN PARIZZI FELIPE , Duarte Pereira Helcio
Published: April 2023

The soybean is a crop that demands high levels of nitrogen (N) to express its productive potential. Supplemental fertilization with N can be a management strategy to increase the yield. This study aims to assess the effect of the N side dressing fertilization at the V4 stage of soybean, with and without inoculation, as well as its effects on the process of biological nitrogen fixation (BNF). The experimental design was randomized complete-block design with four replications in factorial scheme 2 × 5, where the seeds were either inoculated or not and received 5 doses of N: 0, 10, 20, 30, and 40 kg ha−1. Vegetative growth, nodulation, and yield components were evaluated. The stem diameter, plant height, and grain yield were not affected by inoculation, only by the N doses, with positive linear responses to the N supply. The leaf area responded positively to the seed inoculation and to the N supply. The node mass and viable node mass were not altered by seed inoculation or the supply of mineral N; and, until the dose of 40 kg ha−1, the node formation did not decrease. The number of pods per plant and the thousand-grain weight showed an interaction between inoculation and doses of N. The side dressing N fertilization at the V4 stage, until the dose of 40 kg ha−1, did not affect the vegetative growth and BNF, while it contributed to increase grain yield, even in the presence of inoculation.
Initial development of maize plants grown with different combinations of nitrate and ammonium
Authors: Santos Brito Gildeon , Santos de Souza Girlene , Teles de Jesus Neto Alfredo o , Martins de Souza Cristian , Ranulfo dos Santos Anacleto
Published: April 2023

Corn is one of the main commodities of Brazilian agribusiness, due to its wide use, whether for human or animal consumption or in the chemical and biofuel industries. Thus, this work was carried out to evaluate the influence of different proportions of nitrate and ammonium in the initial development of corn plants. The experiment took place in a greenhouse, by direct sowing, where the seeds were placed at a depth of 1 cm in plastic pots with a capacity of 6 dm3 containing a mixture of previously sieved and washed with vermiculite, in a 2:1 ratio. Five proportions of nitrate and ammonium ions (NO3- :NH4+) were used: T1=100:0, T2=75:25, T3=50:50, T4=25:75 and T5=0:100, through nutrient solutions. After 35 days of cultivation, the following were evaluated: plant height, number of leaves, culm diameter, chlorophyll a, b, total and a/b ratio, root length, leaf fresh matter mass, dry matter mass of leaves, culm, roots, total dry mass, and root dry mass/shoot dry mass ratio, leaf area, specific leaf area, leaf area ratio, and leaf mass ratio. Nitrate as the only source of nitrogen provided a smaller increase in the chlorophyll a index of maize plants, which is the most important chlorophyll in the capture of light in the antenna complex. It is not recommended to cultivate corn plants with only nitrate or ammonium; however, it was observed that high doses of nitrate combined with low doses of ammonium in the culture medium provided satisfactory performance for most variables.
The Inhibitory Effects of Lactobacillus Agilis Against Pseudomonas Aeruginosa Biofilm Formation and Evaluation of PpyR (PA2663) and algD Gene Expression
Authors: Issazadeh Yasaman , Farnaghizad Mohadeseh , Falsafi Sarvenaz , Mazaheri Hoora , Ghazi Shokoofeh , Behrouzi Ava
Published: April 2023

Background and Aims: Hospital infections and their antibiotic resistance have become a global concern recently. One of the most prominent factors in hospital infections is Pseudomonas aeruginosa (P. aeruginosa), which can become resistant to many antibiotics due to its ability to form biofilms. Recently, scientists have tried to replace antibiotic therapy with alternative therapies such as probiotics which can reduce or eliminate the pathogenic bacteria's ability to form biofilms. Therefore, the present study revealed that some genes, such as algD and PpyR, were involved in biofilm formation in P. aeruginosa. Furthermore, the inhibitory effect of the supernatant of lactobacillus agilis on the biofilm formation of P. aeruginosa was evaluated in the current study.
Materials and Methods: In this study, the effect of the supernatant of probiotic Lactobacillus agilis on the biofilm formation of P. aeruginosa and also the expression of two genes effective in biofilm formation (algD and PpyR) were investigated. Antibiograms were performed to detect the most resistant bacteria since there is a link between biofilm formation and antibiotic resistance. Further, the effects of probiotics on the expression of PpyR and algD genes were discussed.
Results: Results showed that the biofilm formation of P. aeruginosa was significantly reduced in the presence of lactobacillus agilis.
Conclusions: According to the current study, it could be concluded that because of antibiotics resistance and their associated mechanisms, probiotics could be used as a replacement for antibiotics in many treatments.
MiR-1 Variations in Colorectal Cancer: Possible Implementation as a Potential Accessory Biomarker
Authors: Pirzadeh Elahe , Aghaee-Bakhtiari Seyed Hamid , Yaghoubi Neda , Mahmoudi Ali , Jarahi Lida , Abdollahi Abbas , Hashemy Seyed Isaac , Hasanian Seyed Mahdi , Zahedi Avval Farnaz
Published: April 2023

Background and Aims: Colorectal cancer (CRC) is one of the most common human cancers. Currently, carcinoembryonic antigen (CEA) is used as the main standard biomarker of CRC, though this biomarker is not specifically made for CRC and, in a minority of cases, shows inadequate sensitivity. Therefore, searching for novel accessory biomarkers may fill these gaps in clinical management. miRNAs physiologically regulate various metabolic processes and are misregulated in various cancers. Therefore, the present investigation was conducted to evaluate miR-1 levels in CRC samples.
Materials and Methods: The CRC and adjacent tissue samples were obtained from 24 patients. In addition, sera were collected from the patient group and 24 healthy controls. Total RNA was extracted from tissue samples, and cDNA was synthesized. Real-time PCR determined the expression of miR-1. Serum levels of CEA were also measured using a Monobind ELISA assay kit.
Results: The level of miR-1 in CRC tumors was significantly down-regulated. Moreover, patients with metastasis showed lower expression of miR-1 compared to cases without metastasis; however, this difference was not statistically significant. The ROC curve for miR-1 showed an AUC of 0.69. In addition, ROC analysis revealed a sensitivity of 70.27% and a specificity of 62.96% for miR-1.
Conclusion: There is still a need for new upcoming markers in addition to the main CRC biomarker, CEA. The levels of miR-1 in colorectal cancer tissue samples may provide additional information for the management and follow-up of CRC patients; though, the clinical application needs further studies.
Hematological and Biochemical Parameters of β-Thalassemia Major Patients in Bushehr City: A Comparative Analysis
Authors: Gharehdaghi Zeynab , Rostami Yasuj Shaghayegh
Published: April 2023

Background and Aims: β-thalassemia is the most common genetic disorder worldwide. β-thalassemia major results in severe anemia and serious complications. So, this study aims to evaluate the hematological and biochemical markers in β-thalassemia major patients in Bushehr city.
Materials and Methods: Our study included 94 transfusion-dependent β-thalassemia major were compared with 94 normal healthy subjects as controls. Hematological assessments included complete blood count indices. The biochemical evaluations included liver, kidney, and thyroid function tests, lipid profile, sodium, potassium, calcium, phosphorus, fasting blood sugar, and serum ferritin.
Results: All hematological parameters in patients, such as hemoglobin (p < 0.01), hematocrit (p < 0.01), mean corpuscular volume (p < 0.05), and mean corpuscular hemoglobin (p <0.05), were significantly reduced compared to the control group except mean corpuscular hemoglobin concentration which was insignificant (p > 0.05). Higher levels of triglyceride, phosphorus, fasting blood sugar, aspartate aminotransferase, alanine transaminase, alkaline phosphatase, uric acid, total and direct bilirubin, and lower levels of cholesterol, high-density lipoprotein, and low-density lipoprotein were observed in patients in comparison to the control group (p < 0.05). Serum sodium, potassium, calcium, and albumin was not significantly different from the control group (p > 0.05). The prevalence of primary hypothyroidism (thyroid stimulating hormone > 4.5 mIU/l and T4 < 5.6 μg/dl) was reported at 5.31%.
Conclusions: This study emphasized the necessity for regular follow-up and evaluation of β-thalassemia, which could be used to improve treatment protocols.
desafio em prol da produção textual em tempos de pandemia: um trabalho em conjunto (da escola para casa e de casa para a escola)
Authors: Afonso de Paula Souza Juliana
Published: April 2023

Neste artigo analisamos produções textuais realizadas por alunos do sexto ano do ensino fundamental, nas aulas de Língua Portuguesa no ano de 2020. As análises foram realizadas, após trabalho desenvolvido com sequência didática, elaborada a partir das orientações dos autores Schneuwly e Dolz (2004). Tínhamos como objetivo utilizar uma abordagem para as práticas nas aulas de Língua Portuguesa, sem fazer uso da Gramática Tradicional, integrando leitura, compreensão de texto, análise linguística e produção textual. Nossa proposta foi apresentar atividades aos alunos, a partir de um texto literário, com o intuito de propiciar aos discentes o estudo a partir do próprio texto, e estimulá-los a fazer as suas próprias escritas. Tivemos como foco de nossas análises o gênero textual “relato”, sustentado pelas ideias dos autores Schneuwly & Dolz (2004 p.74) que definem gênero, seguindo Bakhtin (1984), como instrumentos que fundam a possibilidade de comunicação. Neste trabalho, descrevemos nossa experiência iniciada de forma presencial, mas que, devido à pandemia, tiveram de ser realizadas de forma remota. Diante dessa realidade, nossos desafios foram ainda maiores: fazer com que os educandos se interessassem e realizassem as atividades sugeridas de forma remota e conseguir ter acesso aos textos elaborados por eles.
Can Dysfunctional Negative Emotions Explain Students' Level of Academic Motivation in Online Learning at University?
Authors: Florescu Maria Cristina , Bochiș Laura Nicoleta , Barth Karla Melinda , Indrieș Mihaela
Published: April 2023

The study highlights the association relationship between students’ academic motivation level (N=150) and the variables related to dysfunctional negative emotions and physical health. Simultaneously, we analyze whether negative dysfunctional emotions can explain the level of academic motivation, provided that physical health is controlled.
The research method used was a questionnaire-based survey. The working tools were: The Questionnaire for measuring the types of motivation regulation in the academic field (Robu & Tufeanu, 2020), The state of physical health from the Inventory of self-perceived well-being Subscale (Roşeanu & Răşcanu, 2008); Dysfunctional-Negative Emotions Subscale, from The Emotion Measurement Scale (Trip, 2007). According to the research results, the level of academic motivation (more specifically, intrinsic motivation and identification) is inversely associated with the level of negative dysfunctional emotions and directly with the state of physical health, with an average effect size.
However, in the multiple regression analysis, given that the level of health is kept constant, only the level of identification motivation can be explained by the level of dysfunctional negative emotions. In conclusion, we emphasize the role of collaboration in this topic between specialists in education and mental health.
Well-being in Pregnancy. Parameters that Can be Considered in Prenatal SEL Programs
Authors: Abrăcel Maria Magdalena , Leonti Raluca Maria , Muntele Hendreș Daniela
Published: April 2023

This study is among those interested in psychological well-being in pregnant women, exploring the explanatory value for well-being of some parameters such as health consciousness, prenatal expectations, self-perception, taking into account age, and the existence of a preference for birth through caesarean section. In this study voluntarily participated 197 pregnant women (aged between 17 and 46). The questionnaires used were entered in an online form, this form was posted on Facebook groups specific to pregnant women, regardless of age or trimester. In agreement with the first hypothesis (H1) of our study, a significant positive relationship was measured between psychological well-being and health consciousness (c' = .155, p = .0236 < .050). It was also found that health consciousness explains psychological well-being (c' = .155; p = .0236<.050; [.0845; 1.1601]) and prenatal expectations has a partial mediator role in this relationship (a2*b2 = .046, 95 % CI [.0069, .0957]), confirming the hypothesis H2. Moreover, the hypothesis that age (r= .221; p = .0003 < .050) and preference for cesarean (r=-.185; p=. 0026 < .050) are significant covariates of the psychological well-being of pregnant women was confirmed (H4). Our study analyzed the factors that lead to psychological well-being of pregnant women, that would improve the development of the fetus and at the same time a positive development of social emotional learning (SEL) programs.
The Development of Assertiveness of the Individual as a Subject of Communication
Authors: Nikolaiev Leonid , Herasina Svitlana , Hrechanovska Olena , Vlasenko Olha , Skliarenko Serhii , Hrande Kateryna
Published: April 2023

The problem of socialization of the younger generation in general and the development of assertiveness of the individual as a subject of communication, in particular, becomes especially relevant against the background of radical changes in social, political and economic life. The immaturity of the individual's ability to set and implement their own goals and aspirations leads to dissatisfaction with life, the emergence of social fear. Considering the development of assertiveness in neuropsychology, the emphasis is on working with the behavioral and motivational-value range of the individual, which indicates the difficulty of differentiating manifestations of self-confidence and aggressiveness. For the development of confident personality behavior, numerous psychological programs of active social psychological training offer trainings. The purpose is to theoretically identify and empirically investigate the neuropsychological features of the development of assertiveness of adolescents in a children's health institution and secondary school, diagnose neuropsychological factors and present the most pronounced individual psychological qualities of adolescents, which should be identified as psychological reasons that determine the development of assertiveness in adolescence. At different stages of the empirical study, a number of psychodiagnostic techniques were used: the questionnaire "Diagnosis of the assertiveness level"; methods of diagnostics of basic values; SOINT questionnaire; associative experiment with the following procedure of subjective scaling; colour test of relations, test-questionnaire "Emotional orientation"; level of subjective control; personal questionnaire of R. Kettell.
Concept formation and the text in digital culture
Authors: Fadeev Aleksandr
Published: April 2023

During cultural-historical development, our learning processes have evolved to using diverse “symbolic artifacts – signs, symbols, texts, formulae” (Kozulin et al. 2003: 15) as mediators of knowledge and meaning. The phenomenon of a text became one of the most advanced of these mediators, as it goes beyond the mere mediation of knowledge. According to Lotman, the text is a semiotic system “capable of transforming messages received and generating new ones, a generator of information” (1988: 57). The evolution of digital culture and the new media environment have shaped the representation and interaction with texts by “changing the static printed text into a dynamic one” (Ojamaa and Torop 2020: 52). Digitality, multimodality and transmediality became intrinsic characteristics of texts in the new media environment. While this emphasizes the value of acquiring the concept of the text within formal and informal education as an “intellectual device” (Lotman 1988: 55) and a cultural tool for accessing knowledge in digital culture, the semiotic and cognitive processes beyond the acquisition of the concept of the text remain under-researched. The paper represents the first step in the broader study of how young learners acquire the concept of the text in contemporary digital culture. The research aims to identify semiotic processes behind acquiring the concept of the text in digital culture. To this purpose, we introduce Vygotsky's theory of concept formation (2012) as a methodological tool for semiotic research in learning and education.
Javier Iguíñiz : una vida de contribución a la PUCP y al Perú
Authors: Muñoz Portugal Ismael
Published: April 2023

Javier nació en 1945 en el pueblo de Lesaka, en Navarra, España. Lesaka es un pueblo ubicado dentro de la región vasca de la Península Ibérica. Es un pequeño pueblo urbano de aproximadamente 2500 habitantes que casi se convierte en poblado rural cuando salió de allí la familia Iguíñiz-Echeverría.
The evolution of development thought : from growth to human development
Authors: Stewart Frances
Published: April 2023

La primera sección de este documento esboza un marco para considerar la evolución del pensamiento sobre el desarrollo. La siguiente sección proporciona una breve descripción de los principales cambios que ocurrieron. En la sección 4 se proporciona un análisis más detallado de la evolución. La sección 5 lleva brevemente la historia más allá de la introducción del concepto de desarrollo humano en la década de 1990, para considerar el impacto que ha tenido, algunas limitaciones hasta la fecha y los nuevos desafíos del concepto
The political economy of development : the role of institutions
Authors: Jameson Kenneth P
Published: April 2023

Este artículo me brinda la oportunidad de revisar la evolución del debate actual sobre el papel de las instituciones en el desarrollo, apoyándome principalmente en varios artículos que he escrito1. América Latina ha jugado un papel central en el encuadre de este debate, casi como el laboratorio donde se ensayan las teorías. Este fue el caso más tangible con las reformas chilenas de libre mercado de 1975, así que empiezo allí y luego sigo la evolución del debate, enfocándome primero en mi propio tratamiento del tema en varios artículos. Luego paso al debate en torno a un artículo reciente de Ha-Joon Chang (Chang, 2011a) en el que participé.
Dinámicas religiosas y seculares en nuestra era global :más allá de la secularización
Authors: Casanova José
Published: April 2023

Antes de entrar propiamente en el tema de las dinámicas religiosas y seculares de nuestra era global, quisiera comenzar con algunas reflexiones sobre el concepto de «postsecularización», que es el tema de nuestro encuentro. Para ello, voy a resumir brevemente las que considero las tesis más importantes de mi libro Religiones públicas en el mundo moderno (Casanova, 2000b; edición original: Casanova, 1994), una de las cuales es analítica; la otra, crítico-normativa. La primera consiste en disociar analíticamente lo que llamo los tres conceptos que están mezclados dentro de la idea y la teoría general de la secularización; es decir, 1) secularización como diferenciación institucional secular-religiosa, 2) secularización como declive de las prácticas y creencias religiosas y 3) secularización como privatización de la religión.
La secularización en cuestión: aclaraciones sobre el concepto de secularización
Authors: Caviglia Marconi Alessandro
Published: April 2023

La expresión «secularización» y el fenómeno social, político y filosófico que representa han tenido muchas interpretaciones. Los sectores más conservadores han considerado que se trata de un proceso nefasto que ha tenido lugar en las sociedades occidentales a raíz de la modernidad, la Revolución Francesa y la cancelación de las formas políticas, sociales y de pensamiento que campaban durante la Edad Media. Si consideramos que no existe una sino muchas modernidades, tanto en sentido diacrónico como en sentido sincrónico, podemos percibir que durante la primera modernidad y la modernidad expresada por los enciclopedistas, por Rousseau1 y los inspiradores y agentes de la Revolución Francesa, la secularización era entendida del mismo modo en que los sectores conservadores la están entendiendo. Pero en la Ilustración alemana y en otros momentos del proceso de modernización de la cultura, la secularización es entendida de diferentes maneras.
Postsecularización y tolerancia
Authors: Giusti Miguel
Published: April 2023

Si ya el concepto de «postsecularización» es por sí solo materia de serias controversias, evocar a su lado la noción de «tolerancia» puede parecer un modo de hacer las cosas aun más confusas1 . En efecto, más allá de las discrepancias en torno a la interpretación del término «postsecularización», es claro que con él se alude a la caracterización conceptual de un periodo histórico —el proceso de secularización—, y a la proyección de una nueva época (el «post» de la secularización), es decir, a un horizonte cultural inédito pero dentro del cual la tolerancia sería un cuerpo extraño, pues ella surgió en el marco del horizonte previo de la secularización y hasta definió uno de sus rasgos esenciales.