bluuebunny/crossref_metadata_2025 huggingface dataset:
A COMPARATIVE STUDY OF LSVT BIG THERAPY AND BALANCE TRAINING EXERCISES ON BALANCE AND RISK OF FALL IN PARKINSON DISEASE
Authors: Pandian M.Ramaiah , Dhasaradharaman Kannan , Vishnupriya.R  , Anantharaj.K  , Thenmozhi.M.P
Published: June 2024

Background and purpose: Parkinsonism is a degenerative disease of the nervous system involving degeneration of dopamine generating cells. In the early stages of Parkinson's complaint, the face may show little or no expression or the arms may not swing on walking. The speech may come soft or slurred. Although Parkinson's complaint cannot be cured, symptoms get worse when it is not treated on correct time. Objective: To compare the effectiveness of LSVT big therapy and balance training exercise on the balance and risk of falls in Parkinsonpatients. Method: The patient was informed about the whole procedure and treatment method. A written consent was obtained from their voluntary participation in the study. There were 30 patients recruited based on inclusion criteria. They were divided to 2 groups. Each group had 15 subjects. Group A receives LSVT Big therapy, Group B receives balance training exercise. Each patient was given a physiotherapy program for 6 month duration, the pre and post treatment values were measured before and after 6 month for comparison. Result: The result showed that there was statistical significant difference between Group A and B. The Parkinson patients who were treated with LSVT big therapy had shown good improvement in balance and reduce falls. Conclusion: The study which was conducted for 6 months period of intervention showed that Group A of those who received LSVT (Lee Sliver men voice treatment) big therapy resulted in improvement on balance and reduces falls than Group B who received balance training exercises.
Forced Divorce Polemic: Comparative Analysis of the Hanafi and Shafii Schools of Thought
Authors: Muhammad Nirwan Idris  , Kurnaemi Anita
Published: June 2024

This article aims to summarize the views of the Hanafi and Shafii madhhabs regarding the status of divorce of a person who is forced and the method of determining it, as well as to find out the method of scholars in tarjīḥ opinion between the Hanafi and Shafii schools in this case. To get answers to the problems, this article uses library research that focuses on manuscript and text studies, using case and comparative approach methods. By looking at some coercive ḍawābiṭ, the results of the study found that; First, the Hanafis argue that divorce imposed by a person who is forced is legal, because here he faces two tough choices, namely divorcing his wife or receiving threats from the person who forced him, and in fact, he chooses to divorce his wife. In contrast to the Shafii school of thought, which is not consider valid, because divorce is an absolute right for the husband alone, also because Allah has aborted disbelief in those who are forced to disbelieve. The istinbāṭ method of the law used by the Hanafi and Shafii schools is that they both use kias. Second, the scholar's method in tarjīḥ the opinion between the Hanafi school and the Shafii school regarding forced divorce is by looking at the sanad hadith. In this case, the majority of scholars further strengthen the hadiths used as evidence by the Shafii school because they see the ṡīqāh (trusted) narrators of hadith so that all of their narrators can be used as evidence.
Tahfizhul Qur'an Imam Asy-Syatiby High School Students’ Mastery of Fi’il through Studying the Book al-Jāmi’ by Ibnu Ḥajar al-‘Asqalānī (Morfologi Study)
Authors: Muslimin Muslimin , Anwar Abd. Rahman  , Amrah Kasim  , Sirajuddin Sirajuddin
Published: June 2024

The objective of the study was to determine whether the book al-jāmi study method was successful in facilitating students' mastery of the Arabic language learning material, especially material about fi’il. The present study incorporated field research employing qualitative descriptive analysis. The research utilized a variety of data sources including scholarly literature, interview papers, questionnaires, observations, tests, and other supplementary data sources using a phenomenological approach. The findings of this study revealed a limited degree of proficiency among students in regards to the fi’il or verb form, as assessed through the examination of the al-jāmi textbook. Based on the examination outcomes of a sample including 30 pupils, the scores achieved were distributed as follows: 6.7% in the high category, 26.7% in the medium category, 30% in the low category, and 36.7% in the very low category. Based on the given percentage, one might infer that the kids' proficiency in fi’il falls below the established standard or is notably deficient. This phenomenon can be attributed to a variety of factors. Firstly, the absence of any form of evaluation following the study led to decreased motivation among students. Additionally, insufficient emphasis was placed on the importance of recording the material presented, further contributing to the issue. Secondly, the timing of the study sessions was deemed inappropriate, potentially impacting students' ability to absorb and retain information. Based on the findings of this study, it is imperative for the educational institution to assess the program.
Analisis Indeks Kerusakan Pesisir Pantai Berighe'en Di Kabupaten Situbondo Upaya Pelestarian Ekosistem Pesisir
Authors: Purnomo Rinaldy Harjo , Listriyana Ani , Barizy Roqy
Published: June 2024

Pesisir pantai Kabupaten Situbondo, Jawa Timur, Indonesia, adalah ekosistem yang kaya akan keanekaragaman hayati dan memegang peranan penting dalam menyediakan sumber daya alam untuk kehidupan manusia. Namun, seperti banyak wilayah pesisir lainnya, kabupaten ini menghadapi tekanan kerusakan akibat aktivitas manusia dan perubahan iklim global. Tantangan utama meliputi perubahan pola penggunaan lahan, peningkatan pembangunan pesisir, dan eksploitasi sumber daya alam laut. Untuk mengukur dan memahami tingkat kerusakan pesisir, pengembangan indeks kerusakan pesisir menjadi penting sebagai alat evaluasi dampak berbagai faktor terhadap kesehatan ekosistem pesisir. Kabupaten Situbondo, dengan keindahan alam uniknya, termasuk ekosistem hutan mangrove, terumbu karang, dan kehidupan laut yang beragam, mengalami tekanan signifikan dari pertumbuhan populasi dan aktivitas manusia. Perubahan iklim yang termanifestasi dalam kenaikan suhu air laut, permukaan laut, dan intensitas badai yang lebih tinggi semakin meningkatkan kerentanan pesisir terhadap kerusakan. Penelitian ini bertujuan untuk mengembangkan dan menerapkan indeks kerusakan pesisir di Pantai Berighe'en, Kabupaten Situbondo. Dengan melibatkan parameter fisik, biologis, kimia, dan sosio-ekonomi, indeks ini diharapkan memberikan gambaran komprehensif tentang kondisi pesisir dan tingkat kerusakannya, sambil mengidentifikasi faktor-faktor utama yang berkontribusi terhadap kerusakan pesisir. Metodologi analisis IKP melibatkan enam variabel, termasuk perubahan garis pantai, intensitas badai, populasi, sumber daya air, sumber daya pesisir, dan infrastruktur pesisir. Pembobotan variabel dilakukan dengan membagi nilai variabel ke dalam lima tingkatan kerusakan. Hasil analisis IKP di Pantai Berighe'en menunjukkan nilai sebesar 16,32, menandakan tingkat kerentanan pesisir yang rendah. Kesimpulannya, Kabupaten Situbondo dihadapkan pada tantangan signifikan terkait kerusakan pesisir. Meskipun demikian, nilai IKP yang rendah di Pantai Berighe'en menunjukkan adanya potensi untuk merancang strategi pelestarian efektif guna menjaga ekosistem pesisir yang berharga. Oleh karena itu, perlunya upaya pelestarian yang mendesak dan penerapan indeks kerusakan pesisir untuk identifikasi area yang memerlukan perhatian khusus dan pengembangan strategi pelestarian berkelanjutan
Identifikasi Jenis Fouling Organisme Wilayah Bahari Lestari di Desa Mayangan, Kecamatan Gumukmas, Kabupaten Jember
Authors: Rifki Ahmad , Prasasti Arindana Dwi , D Adelia Septhiana , Syahputra Ardian , Sakinah Wazirotus , Saifurridzal Saifurridzal , Pahlewi Anita Diah
Published: June 2024

this research to identify fouling organism types that can impact the sustainability of the Lestari marine region. In efforts to preserve the environment and support water resource management, the study aims to develop a comprehensive understanding of the dominant fouling organisms in this area and their potential impacts. Through this identification, it is hoped that suitable prevention and mitigation strategies can be developed to maintain the balance of the coastal ecosystem. The method used is sampling in the form of pictures and direct descriptive exploration, while identification of attached biota and mangrove types is carried out using descriptive information. The research results showed that the dominant biota came from bivalves with the type Saccostrea cucullata from the genus Ostreidae. Mangrove species are growing naturally or through replanting efforts in Mayangan Village, Gumukmas District, Jember Regency
Chasing shadows: Investigating X chromosome mediation in late-onset Alzheimer’s disease
Authors: Armon Carmel , A. Cannon-Albright Lisa , Allen-Brady Kristina , Wolfson Sharon
Published: June 2024

Alzheimer’s disease (AD) is a major cause of dementia. While maternal inheritance has been recognized for late-onset AD (LOAD), risk factors have not been identified consistently on the X chromosome. We recently developed a new method to identify an apparent risk of 70% mediated by the X chromosome in newly-presenting cognitive disorders clinic patients with amnestic mild cognitive impairment (aMCI) or early LOAD with unilateral parental lineage for AD or dementia. We sought to confirm our preliminary findings in the Utah Population Database (UPDB). We obtained previously published aggregate data on the risk of AD in the UPDB based on family history, stratified the data by the sex of the proband, and analyzed them using the new method. The X chromosome-attributable relative risk was estimated by calculating the following: Odds ratio (OR) = (women with paternal lineage: Women with maternal lineage)/(men with paternal lineage: Men with maternal lineage). The proportion of genetic risk attributable to the X chromosome is equal to (OR-1)/OR. The analysis did not reveal any risk mediated by the X chromosome, and the null result could be attributed to methodological limitations. Factors that impact the initial or early presentation (incidence) of LOAD, which are appropriate for consideration as risk factors, may not be detectable in a (prevalent) population of deceased individuals. Thus, epidemiological evidence for the contribution of the X chromosome to the development of LOAD will need to be sought prospectively in incident patient populations with newly diagnosed, biologically-confirmed aMCI or LOAD.
Staged wound reconstruction utilizing regenerative dermal matrix followed by split-thickness skin grafting in the setting of local radiation: A case series with review of the literature
Authors: S. Baruch Emily , M. Crawford Kristina , R. Endara Matthew
Published: June 2024

The use of radiation for local control following tumor extirpation has improved outcomes across the spectrum of oncologic conditions. Reconstructive strategies that improve short-term healing rates and long-term results in these complicated wound healing environments are paramount to success. Regenerative dermal matrices (RDM) have emerged as viable options to improve reconstructive outcomes in the field of radiology. Here, we present a case series highlighting our algorithm of staged reconstruction using regenerative dermal matrix followed by split-thickness skin grafting to reconstruct skin deficits following excision of tumors either before or after radiation. A systematic review of the literature pertaining to irradiated wound closure and the application of dermal regenerative templates is presented to better understand its emerging role to manage these complex cases and impact future outcomes. Six patients underwent staged reconstruction using our algorithm, all of which went on to heal completely without additional procedures or evidence of skin breakdown in the short and long term. RDMs seem to improve the radioresistance of surgically reconstructed wounds following excision of cancer. The mechanism for this is likely related to the creation of additional tissue layers beyond those replaced with skin graft alone and should be the subject of future study.
Hashimoto’s thyroiditis presenting solely with psychotic symptoms: A case report
Authors: Liu Xiaoxi , Jiang Wenhao , Yue Yingying , Yuan Yonggui
Published: June 2024

This case report highlights the infrequent occurrences of myxedema psychosis and pituitary hyperplasia as secondary complications of Hashimoto’s thyroiditis. The subject of interest is a 16-year-old female patient who displayed persistent symptoms of delusions, auditory hallucinations, and depression without any discernible cause. The physical examination did not reveal any notable abnormalities. Despite a continuous 4-week treatment regimen involving antipsychotic and antidepressant medications, the patient experienced a deterioration of psychotic symptoms, which resulted in substantial impairment in social functioning. Cranial magnetic resonance imaging scan detected an enlarged pituitary gland and laboratory tests indicated abnormal thyroid function and the presence of specific thyroiditis autoantibodies. Combined with these results, thyroid ultrasound findings revealed features that were consistent with Hashimoto’s thyroiditis. Consequently, the patient was prescribed levothyroxine sodium replacement therapy, as well as low-dose antipsychotic and antidepressant medications, which led to a gradual amelioration of their psychotic symptoms. Following 6 months of treatment, the patient was ordered to stop taking the antipsychotic and antidepressant drugs but continue with levothyroxine sodium replacement therapy exclusively. The results of the 1-year follow-up demonstrated the restoration of thyroid function to normal levels, the normalization of pituitary size and structure, and the absence of any psychotic symptoms. These findings provide evidence for a diagnosis of myxedema psychosis and secondary pituitary hyperplasia caused by hypothyroidism associated with Hashimoto’s thyroiditis. This emphasizes the significance of supplementary tests in the diagnostic procedures carried out by psychiatrists.
Curriculum, Curricular Justice, and Mathematics Education: a political manifesto
Authors: Taveira Flavio Augusto Leite
Published: June 2024

This study aims to carry out a systematic literature review on curricular justice in mathematics education in databases that offer privileged spaces for disseminating knowledge about the curriculum-mathematics education binomial. Since this review offers no results, it discusses how some publications on the curricular debate in mathematics education approach Robert Connell’s theorization on curricular justice. Thus, this review defends the need to think about curricular justice in mathematics education in our times and states that no production focuses on discussions about issues of curricular justice in privileged spaces for disseminating curricular knowledge in mathematics education, exemplifying the scarcity of this debate in Brazilian mathematics education.
Addiction a Complex Syndrome
Authors: Butt Ammara
Published: June 2024

Addiction is a complex and multifaceted issue that affects millions of people worldwide. It has the potential to ruin lives, destroy families, and damage communities. Addiction can be defined as a compulsive and uncontrollable urge to engage in a particular behaviour, despite the negative consequences that may result.1 It can take many forms, from alcohol and drugs to gambling, sex, and even food. Addictive behaviours have a profound impact on individuals and society as a whole.
          The origin of addiction is still a topic of debate among scholars and researchers, with some pointing to genetic predispositions and others highlighting environmental factors such as childhood trauma and stress. Whatever the cause, addiction is a chronic condition that requires support, understanding, and intervention to overcome.2
          One of the most significant challenges of addiction is that it is often associated with negative stigmas, shame, and guilt. Many people who struggle with addiction do so in silence, afraid to seek help or admit they have a problem. This stigma can make it difficult for individuals to access the resources and support they need to overcome their addiction.3
The Surgical Management of Epilepsy - A Surgeon Perspective
Authors: Hameed Abdul
Published: June 2024

Epilepsy is stereotypical clinical manifestation of recurrent, paroxysmal, excessive, synchronous neuronal activity of cerebral cortex. It affects almost 50 million people world wide1 . The incidence of epilepsy is as high as 50- 60 per 100,000. A range of 4 to 10 per 100,000 person per year makes it one of the most prevalent neurological disorder. Its prevalence in Pakistan touches the upper boundary of world’s prevalence, being 9.99 per 1000 people. It is more prevalent in persons younger then 30 years and it is more prevalent in rural areas2.
          For a medical personal it may be a clinical scenario but for the affected person it is a big social stigma. Patients suffering from this disease are usually isolated, depressed and deprived of many social rights. Although considered to be disease of high IQ people, every successive fit cause a certain amount of cognitive damage to the affected patient and it can be potentially lethal for the patient and for society if these people have adopted certain professions.
          For a county like Pakistan where economy is touching its nadir it is highly difficult for patients to comply with adequate antiepileptic drug (AED) therapy.
          One should clearly differentiate between seizure and epilepsy. A seizure is defined as a “Transient occurrence of signs and symptoms due to abnormaly excessive and synchronous neuronal activity in the brain.” For practical purposes epilepsy can be defined as;

At least two un provoked (or reflex) seizures occurring > 24 hours apart.
One unprovoked (or reflex) seizure and probability of further seizures
Diagnosis of an epilepsy syndrome.

          Monotherapy is ideal for treatment and control of epilepsy. With increase of number of AEDs the chances of epilepsy control decrease. Surgery is potentially curative for epilepsy or at least it is helpful for reduction of demand of AEDs in carefully selected patients.
          International League Against Epilepsy (ILAE) gives its recommendations for selection of surgical candidates.
Government Policies in Combating COVID-19 Pandemic in Pakistan: A Gender-based Perspective
Authors: Qureshi Irum , Manzoor Iram , Tahir Fatima , Nadeem Hubba , Islahuddin Husnain , Iftikhar Hijab
Published: June 2024

Background: One of the most significant determinants of risk perceptions and coping mechanisms is gender, which reflects the public's propensity to embrace health initiatives and exercise caution. This study aims to understand the gender differences in perspective regarding government policies in combating COVID-19 pandemic.
Subjects and methods: This analytical cross-sectional study was conducted as an online google survey from April to September 2021 in Lahore using a non-probability convenience sampling technique. SPSS version 23 was used for the analysis of the data, which was gathered using a self-structured questionnaire from 200 participants. Chi-square test was applied to deal with qualitative variables and a p-value <0.05 was considered significant.
Results: Out of 200 respondents, 92(46%) were males and 108(54%) were females. Mean age of the participants was 25.8+ 6.6years. Significant differences were found in perceptions between males & females in containing Corona virus by putting restrictions on wedding halls and social gatherings (p-value=0.05) as well as government’s decision of closing the educational institutions and online learning classes (p-value=0.035). Significant differences were also seen in perceptions of both genders regarding strict punishment for those who break SOP’s in form of fines (p-value=0.001), vaccination mandatory for every individual (p-value=0.008) and PCR diagnostic test should be done free of cost (p-value=0.003).
Conclusion: Women are more inclined to agree with and follow restraining measures and laws, and to view the pandemic as a very serious health issue. This data reveals a realm of gender disparities as well as behavioral changes in reaction to a new risk, which has significant implications for gender-based public health policy and COVID-19 communication.
Efficacy and safety of Narrowband UVB in Chronic Plaque Psoriasis in Skin type IV and V
Authors: Rafiq Zahid , Anwar Ahsan , Hoor Shahana , Kouser Humaira , Salam Sana us , Qibtia Maria
Published: June 2024

Background: Narrowband (NB) UVB phototherapy is considered practically to be an effective and safe modality as compared to other systemic therapies and Broad band UVB phototherapy for management of psoriasis. The objective of the study was to determine the efficacy of narrowband UVB in chronic plaque psoriasis in skin type IV and V.
Patients & Methods: A Qausi experimental study was carried out in Dermatology Department, Sahiwal Teaching Hospital, for one-year duration from March 2022 to February 2023. Patients of both gender and age between 16 and 65 years were included. All the patients were exposed to thrice weekly sessions of narrowband UVB with starting dose of 280mj with 10 % increment weekly. Efficacy was assessed at baseline and then at 4th, 8th and 12th week by PASI (Psoriatic Area and Severity Index). All research data was noted on predesigned proforma and was analyzed by using SPSS version 26.
Results: Thirty-one patients were enrolled with male to female ratio of 23:8. The baseline mean PASI score was 16.62±6.03, and it significantly decreased to 2.77±1.70 after the 12-week follow-up, indicating the effectiveness of NUVB phototherapy in the treatment of chronic plaque psoriasis (P-value<0.05). Pruritus 22.6 %(n=7) was the common side effects noted followed by painful erythema 9.7 %(n=3).
Conclusion: Narrowband UVB has demonstrated to be effective and safe therapy in the treatment of psoriasis. This therapy typically results in fewer side effects.
Mat Salleh sebagai Tokoh Perpaduan Sabah dalam Novel Tibabar: Benteng Terakhir Panglima Mat Salleh Berdasarkan Perspektif Historisisme Baru
Authors: Mohamad Zaki Muhammad Zahid , Ismail Hashim , Mamat @ Mustaffa Madiawati
Published: June 2024

Kajian ini bertujuan untuk menganalisis aspek ketokohan Mat Salleh sebagai tokoh perpaduan Sabah dan mengangkat nilai Islam yang dibawa dalam perjuangan Mat Salleh dalam novel sejarah, Tibabar: Benteng Terakhir Panglima Mat Salleh (2013) karya Roziah Adama. Kajian ini dijalankan berdasarkan sorotan literatur yang mendapati bahawa wujud perubahan persepsi masyarakat terhadap perjuangan Datu Paduka Mat Salleh jika diteliti sebelum dan sesudah Sabah mencapai kemerdekaan melalui pembentukan Malaysia. Lantaran itu, pemaknaan baharu watak Mat Salleh sebagai tokoh pembebasan Sabah dalam novel ini wajar diberikan perhatian oleh pengkaji sejarah khususnya dalam melihat dimensi perubahan pemikiran masyarakat yang tidak lagi menganggap Mat Salleh sebagai pemberontak. Sebagai salah satu daripada bentuk karya sastera, setiap novel yang baik mengandungi elemen politik dan sejarah yang disepadukan melalui penceritaan yang memberikan pengetahuan baru, keseronokan dan menyembunyikan idealisme pengarang terhadap sesuatu isu yang diketengahkan dalam karya. Maka, kajian ini memanfaatkan gagasan teori Historisisme Baru yang dikemukakan oleh Stephen Greenblatt (1988) sebagai kerangka analisis. Dapatan kajian menunjukkan bahawa usaha pemaknaan baharu dilakukan secara sedar dalam karya ini demi mengangkat Panglima Mat Salleh sebagai wira serta menolak wacana kolonial yang menyifatkan Mat Salleh sebagai penjenayah atau pemberontak. Dapatan kajian ini turut menunjukkan bahawa Mat Salleh merupakan tokoh yang menyatupadukan masyarakat Sabah serta membawa agama Islam sebagai dasar perjuangannya.
Study on the separation effects of the novel collector ODD on magnesite and quartz
Authors: Gao Gui , Sun Haoran , Wang Yulian , Sun Yishen , Han Huili , Yuan Zhigang
Published: June 2024

Traditional magnesite desilication flotation collectors struggle to efficiently remove quartz from low-grade magnesite, prompting the exploration of new, highly selective flotation collectors. Addressing this need has become a focal point in mineral processing research. This study introduced heptadecylamine ethylimidazoline quaternary ammonium salt (ODD) as a quartz flotation collector for separating quartz from magnesite. Flotation experiments involving single minerals and artificially mixed minerals demonstrated that magnesite and quartz could be effectively separated under specific conditions: an ODD concentration of 40mg/L and pH=7.0. Zeta potential assessments revealed that the adsorption of ODD increased the potential of quartz by 4.4 times compared to magnesite. Furthermore, contact angle measurements illustrated that ODD selectively increased the hydrophobicity of the quartz surface while not affecting the contact angle of magnesite. X-ray photoelectron spectroscopy (XPS) analysis indicated that ODD's selective adsorption at the quartz surface through interaction with the O sites on quartz rather than magnesite. Drawing from these findings, a flotation separation model from magnesite and quartz under the influence of ODD was formulated.
Iman yang Bertumbuh dalam Tindakan: Implikasi Konsep Tabula Rasa dan Pendidikan Ekologi bagi Anak Sekolah Minggu Huria Kristen Batak Protestan
Authors: Manalu Musdodi
Published: June 2024

This article explores the integration between John Locke's concept of tabula rasa and ecological education for Sunday School children in the Huria Kristen Batak Protestan (HKBP) Church. The research aims to investigate how Locke's philosophical concept of the mind as an empty "tabula rasa," which is filled through experience and learning, can be applied in the context of children's faith growth. The main focus is on ecological education, where the article explains how a holistic approach to faith growth involves children's understanding of their relationship with nature and the surrounding community. This concept is explicitly applied in HKBP Sunday School, highlighting the church's efforts in delivering religious teachings and facilitating hands-on experiences that can shape children's faith. Combining Locke's and Susan Power Bratton's thoughts on ecological education, this article offers insights into how faith can develop through action and tangible experiences, creating a solid foundation for children's spiritual growth in an ecologically conscious ecclesial environment and active learning. The research method used was a literature review that included books, journal articles, and news related to ecological education. The research used thematic analysis to identify and report patterns or themes in the data obtained from literature sources. The main contribution of this research is the integration of ecological principles in the context of children's worship as embodied in the HKBP Sunday School Handbook, updated annually.
Pengaruh Return On Asset (ROA) dan Earning Per Share (EPS) Terhadap Harga Saham Pada PT. Mitra Keluarga Karyasehat, Tbk.
Authors: Rostini Rostini , Ismail Muhammad , Bakri Risna Melati Sukma , Goeliling Ardhi , Iriani Nisma
Published: June 2024

This research aims to investigate the influence of Return On Asset (ROA) and Earning Per Share (EPS) on stock prices at PT. Mitra Keluarga Karyasehat Tbk, a healthcare service company listed on the Indonesia Stock Exchange. Data for the study were obtained from the company's financial reports retrieved from the official website of the Indonesia Stock Exchange. The research method employed was literature review, analyzing relevant literature to understand the company profile and fundamental concepts related to ROA, EPS, and stock prices. Quantitative data from financial reports were used for empirical analysis. The findings indicate a significant relationship between ROA, EPS, and the stock price of PT. Mitra Keluarga Karyasehat Tbk. These findings provide valuable insights for investors and company management in developing effective investment strategies. This research contributes significantly to understanding the factors influencing stock prices of companies in the Indonesian equity market, as well as their implications for investment decisions and company management.
PENGARUH SIKAP KEUANGAN, PENDAPATAN, DAN GENDER TERHADAP PENGELOLAAN KEUANGAN KELUARGA
Authors: Ramadhani Mardiatul , Rissi Dita Maretha , Sriyunianti Fera
Published: June 2024

This study aims to determine and analyze the effect of financial attitudes, income and gender in family financial management. This study is a type of quantitative. The data used in this study is primary data with a data collection method using questionnaire sheets distributed to respondents. The population of this study is people who live in South Nagari Kajai West Pasaman.  The sample in this study was 150 respondents. The sampling technique in this study is convenience sampling. The analysis method in this study uses multiple linear regression analysis using the SPSS version 25 application. The results of this study show that partial  financial attitudes, income and gender have a significant effect in family financial management in Nagari Kajai Selatan, West Pasaman.  Simultaneously that financial attitudes, income and gender together have effect in family financial management in South Nagari Kajai West Pasaman.
SYSTEMATIC LITERATURE REVIEW: DAMPAK INVESTASI PENDIDIKAN TERHADAP KEMAJUAN EKONOMI
Authors: Rahmanto Andi Adam , Wijayanti Veronica Cynthia , Rahmawati Diya Rofika , Arninasari Aprilia Nur , Indriayu Mintasih
Published: June 2024

Investments made in the education sector are an investment strategy that allocates costs for providing education in a country. The aim of preparing this research is to determine the impact of educational investment on a country's economic progress. The method used in this research is a Systematic Literature Review (SLR). This research shows that educational investment has an important role in economic growth, but its impact varies depending on the regional context and the policies implemented. The importance of policy and funding reforms to improve the quality of education is also highlighted, while restrictions on investment in basic scientific inquiry are noted. Appropriate strategies in allocating educational resources are needed to optimize their benefits, especially in less developed areas. This research concludes that education is considered an important strategic investment for the development of human resources and the economic growth of a country. With educational investments ranging from early childhood education to higher education, positive impacts include increased productivity and reduced poverty in the long term.
PENGARUH PERSEPSI SISWA TENTANG KARAKTERISTIK GURU MATEMATIKA TERHADAP PRESTASI BELAJAR MATEMATIKA
Authors: Tawa Emma Maria Sada , Jagom Yohanes Ovaritus , Kaluge Agapitus Hendrikus
Published: June 2024

This research aims to: (1) determine the perceptions of class VIII students regarding the characteristics of mathematics teachers at SMPN 2 Kupang; (2) determine the mathematics learning achievement of class VIII students at SMPN 2 Kupang; and (3) determine the influence of class VIII students' perceptions regarding the characteristics of mathematics teachers on mathematics learning achievement at SMPN 2 Kupang.. This research uses a simple regression analysis approach. The population in this study were class VIII students of SMPN 2 Kupang. The sample in this study was 30 students obtained through the cluster random sampling method. The data collection techniques used were questionnaires and tests. Data analysis was carried out descriptively and inferentially using SPSS 23. Descriptive research results showed that some students had a good perception of the characteristics of mathematics teachers with a good percentage 66.67% and had good mathematics learning achievement with a good percentage 83.3%. Inferentially shows there a significant influence between students' perceptions of the characteristics of mathematics teachers on mathematics learning achievement as indicated by the value of tcount (2,714) < ttable (1,701)   at the 5% significance level which means that H0 is rejected and there is a large influence of students' perceptions of the characteristics of mathematics teachers on achievement. studying mathematics is 20.8%.
Lessons of reading Russian classics in the training of foreign Russian philologists
Authors: Кулибина Н.В.
Published: June 2024

Автор статьи обосновывает необходимость включения уроков чтения художественной литературы в подготовку иностранных филологов-русистов, описывает интерактивную методику обучения чтению сложных (в том числе художественных) текстов, а также представляет новый проект Института Пушкина – галерею открытых мультимедийных образовательных комплексов «Русская классика на интерактивном уроке чтения».

The author of the article substantiates the need to include fiction reading lessons in the training of foreign Russian philologists, describes an interactive methodology for teaching reading complex (including artistic) texts, and also presents a new project of the Pushkin Institute – a gallery of open multimedia educational complexes «Russian Classics in an interactive reading lesson».
Comparative analysis of fables in the context of studying Russian literature in a foreign language audience
Authors: Супрунова Д.А.
Published: June 2024

Статья посвящена сравнительному анализу басен, написанных тремя русскими поэтами XVIII – начала XIX вв. на известный сюжет о Дубе и Трости (Тростнике). Сохраняя сюжетную общность, произведения А. П. Сумарокова, Я. Б. Княжнина и И. А. Крылова заметно отличаются диалого-монологической структурой, характеристиками персонажей и лексическим составом. На основании различий делается вывод о культурологическом и лингвостилистическом потенциале изучения басен со сходным сюжетом на уроках литературы в иноязычной аудитории.

The article reveals a comparative analysis of fables written by three Russian poets of the 18th – early 19th centuries on the well-known plot of the Oak and the Cane (Reed). While maintaining the plot commonality, the works of A. P. Sumarokova, Ya. B. Knyazhnin and I. A. Krylov's works are noticeably different in their dialogue-monological structure, character characteristics and lexical composition. Basing on the differences, the author makes conclusion about the cultural and linguistic-stylistic potential of studying fables with a similar plot in literature lessons in a foreign language audience.
The problem of the spiritual rebirth of personality in the works of I. S. Shmelev and N. V. Agafonov (in the classroom in a foreign language audience)
Authors: Леонов И.С.
Published: June 2024

В статье рассматриваются методические подходы к изучению в иноязычной аудитории (уровень В1–В2) рассказа И. С. Шмелева «Глас в нощи» и современного российского автора Николая Агафонова «Чудо в степи». В сравнительно-сопоставительном аспекте раскрываются общие черты поэтики обоих рассказов, отражение в них евангельских ценностей, ориентация на христианскую аксиологию, символика образа дороги.

The article discusses methodological approaches to studying in a foreign language audience (level B 1-B 2) the story of I. S. Shmelev Voice in the night and the modern Russian author Nikolai Agafonov Miracle in the Steppe. In a comparative aspect, the common features of the poetics of both stories are considered, the reflection of evangelical values in them, orientation to Christian axiology, and the symbolism of the image of the road.
COMBINED DETERMINATION OF THE SMALL INTESTINE WALLS LUMINESCENCE INTENSITY TO ASSESS ITS VIABILITY
Authors: Horditsa V. V. , Grynchuk F. V.
Published: June 2024

Resume. Aim: to study the informativeness of the photoluminescence intensity (PLI) indicators of the small intestine walls to assess its viability.
Material and methods. 30 white rats with small bowel obstruction models in the initial (10 rats), middle (10 rats), terminal parts. In 6 h, the intestines were irradiated with a laser beam (λ=458 nm). After measuring PLI, intestinal tissues were taken for histological examination. The examination data of 10 intact rats were the control.
Results. PLI is significantly decreases if viability is disrupted. Parameters of absolute indicators have significant local and individual variability. Using the ratio of PLI parameters at wavelengths λ=474 and λ=489 nm eliminates variability. The parameters of the ratio differ significantly, depending on the degree of viability disruption.
Conclusions. 1. Viability disruption of the small intestine are associated with a significant decrease in the ratio parameters of the its walls luminescence intensity indicators at the wavelengths λ=474 and λ=489 nm.

Ratio parameters > 20 un mark preserved viability, parameters within 17-13 un mark morphological disorders without necrosis, parameters < 12 un mark necrotic disorders.
EVOLUTION OF DIAGNOSIS AND TREATMENT OF ACUTE PANCREATITIS
Authors: Lupaltsоv V. I.
Published: June 2024

Goal. To show that despite the unwavering attention of clinicians to the problem of acute pancreatitis, late diagnosis or its errors, inadequate choice of conservative treatment tactics without taking into account the pathogenetic mechanisms of its development continue to be among the reasons for unsatisfactory treatment.
Introduction. The article demonstrates the unrelenting attention of clinicians to the problem of acute pancreatitis (AP). It is noted that new instrumental diagnostic methods have been introduced into clinical practice: ultrasound, CT, selective celiacography, etc. Minimally invasive surgical techniques have taken a strong place in diagnosis and treatment. At the same time, it is emphasized that despite the widespread introduction of the latest diagnostic technologies and treatment protocols into clinical practice over the past decades, treatment results have not changed significantly. The reason for unsatisfactory treatment results continues to be late diagnosis or its errors, inadequate choice of conservative therapy and surgical techniques without taking into account the pathogenetic mechanisms of its development. The main problem in improving treatment results continues to be the influence of treatment tactics on the development of pancreatic necrosis of the pancreas (PG), parapancreatic tissue and mediastinal tissue. The authors emphasize that although intraorgan thrombosis of the pancreas in AP has been noted by many researchers, there is no common point of view on their formation. Taking this into account, they conducted studies of AP on various models of acute experimental pancreatitis, biopsy material from operated patients and materials from sectional studies. The authors emphasize that although intraorgan thrombosis of the pancreas in AP has been noted by many researchers, there is no common point of view on their formation. Taking this into account, they conducted studies of AP on various models of acute experimental pancreatitis, biopsy material from operated patients and materials from sectional studies. Improving the results of treatment of AP will be facilitated by improving diagnostic methods and survival rates associated with the drug component, taking into account the pathological mechanisms of aggression associated with disorders of microcirculation and hemorheology.
MICROBIOLOGICAL STUDY OF BILE IN PATIENTS WITH ACUTE PURULENT CHOLANGITIS
Authors: Boyko V. V. , Smachilo Р. M. , Maloshtan А. V. , Likhman V. M. , Brovkin V. Y. , Omelchenko V. F.
Published: June 2024

Abstract. Bacteremia and endotoxemia are observed in patients with acute purulent cholangitis. Infection of the biliary system can occur in different ways: ascending (enterogenic), descending (hematogenic) and lymphogenic. To date, there is no complete clarity about each of the ways bacteria enter the bile. The prevailing opinion is that the most common cause of biliary colonization is enterogenic and lymphogenic spread of microorganisms from the intestine. For the development of infection, penetration into the bile is not enough. Along with bile stagnation, damage to the bile duct mucosa and changes in the physicochemical properties of bile are important.
The aim of the study. To conduct a bacteriological study of bile microflora and to find out its role in the etiology of acute purulent cholangitis.
Materials and methods. To characterize the microflora, to clarify its role in the etiology of acute purulent cholangitis, as well as for the purpose of dynamic monitoring of bacterial contamination of bile, its bacteriological study was performed. Bacteriologic examination of bile was performed in 101 patients with acute purulent cholangitis with mechanical jaundice of non-tumor origin.
The results. Positive cultures were obtained in all patients. The analysis of bacteriological studies showed that in 89,1% of patients the cause of acute purulent cholangitis was the association of aerobic and anaerobic microorganisms. In 6,9% of patients, only nonclostridial anaerobes were sown, in 4% – only aerobes. The analysis of the species structure of the bile microflora revealed the following: the aerobic revealed the following: the aerobic spectrum of the bacterial flora was represented by various enterobacteria, Escherichia coli, various types of Proteus, staphylococci, and streptococci. E. coli was the dominant infectious agent.
Conclusions. A correlation between the severity of the disease and the nature of the bile microflora was found. In patients with severe purulent intoxication and severe liver failure, associations of Escherichia coli and bacteroids were involved in the inflammatory process, among which Bact. Fragilis. The data obtained are of great importance for the complex therapy of acute purulent cholangitis.
EFFICIENCY OF EARLY USE OF LYMPHOTROPIC ANTIBACTERIAL THERAPY IN PATIENTS WITH ACUTE PANCREATITIS
Authors: Duzhyi I. D. , Sytnik O. L. , Piatykop H. I. , Khakhaliev M. A. , Symonenko I. A.
Published: June 2024

Abstract. Acute pancreatitis (AP) is an urgent surgical disease. In the etiology and pathogenesis of acute pancreatitis, several external and internal factors contribute to the contamination of micro- and macronecrosis with acute intestinal microflora, the formation of infected acute pancreatitis (IAP), and multiple organ failure (MOF). Lethality is in the range of 7–15 – 40–70 %. One of the ways to optimize treatment is antibiotic therapy along with improving medication routes of administration.
Aim. To compare the effectiveness of antibiotic therapy with different medication routes of administration, studying the degree of intoxication on the background of changes in the proteolytic system.
Materials and methods. The influence of standard and lymphotropic antibiotic therapy on the clinical course and dynamics of intoxication syndromes on the background of changes in the parameters of the proteolytic system was studied.
Results and discussion. During early hospitalization (up to 24 h), the level of neutrophil elastase (NE) decreased on the 5th day under the influence of lymphotropic therapy by 154,2 nmol/min, and during late hospitalization (after 24 h) with the same therapy – by 126,2 nmol/min, while with standard antibacterial therapy in the first subgroup, the reduction occurred by 85,8 nmol/min, and in the second subgroup by 89,8 nmol/min. In accordance with changes in NE, there was a synchronous decrease in intoxication indicators.
Conclusions. The intensity of inflammatory changes in the pancreas depends on the duration of the process. With lymphotropic therapy, the better dynamics of NE indicators exceed those of standard antibacterial therapy.
APPLICATION OF VULNEROSORPTION IN THE COMPLEX TREATMENT OF WOUNDS
Authors: Kanikovskyi O. , Bondarchuk O. , Sander S. , Hnatiuk Y.
Published: June 2024

Abstract. The goal is to analyze the experience of using vulnerosorption in the treatment of peacetime wounds with the prospect of using it in the treatment of gunshot wounds. Materials and methods. There were 270 patients under observation: primary purulent wounds – 216, traumatic wounds – 54. After surgical treatment, the wounds were washed with a 1-3 % aqueous suspension of amorphous highly dispersed silicon dioxide (AHDSD) and drained. The drug was applied in a layer of 3-7 mm. Dressings were performed daily until the wound was cleaned. The clinical dynamics of the wound process and bacterial seeding of the wound were evaluated. The osmotic and sorption (protein, microorganisms) activity of AHDSD was studied. In the ATO zone, 22 wounded were treated with wound dressings based on AWDK during the first level of care.
Results and their discussion. Protein sorption is 320 mg/g, microorganisms – 1010 colony-forming units (CFU). AHDSD is devoid of selective sorption and does not cause the selection of resistant strains. Osmotic activity of AHDSD – (503.0±7.3) %, water absorption – (944.1±15.1) %. In primary purulent wounds, the exudate became more liquid from the second day, the wounds were cleaned in (4.9±0.2) days, granulations appeared in (3.5±0.2) days, the beginning of epithelization in (6.8±0.4) days The need to use antibiotics arose in 47.2 % of patients. During 7 days, the bacterial seeding decreased from (8.4±0.7) (lg CFU/cm2) to (4.8±0.1) (lg CFU/cm2), the protein concentration in the exudate – from (53.1±2.3) g/l to (22.7±1.8) g/l. In case of traumatic wounds, the use of AVDC contributed to the successful completion of primary surgical treatment with the application of primary sutures in 52 of 54 patients. Suppuration occurred in 3 patients (5.8 %). In the case of secondary healing, application of AHDSD made it possible to apply secondary early sutures on the 8-11th day. Wound dressings based on AHDSD were applied to 22 wounded with gunshot wounds at the 1st level of care. Hemostatic action is noted. Therefore, AHDSD meets most of the requirements for drugs for local treatment in the first phase of the wound process. The results of treatment using AHDSD are comparable to the results of treatment by the NPWT method. Conclusion. Vulnerosorption using AHDSD is an effective and promising method of treating wounds at various stages of care.
MULTISTAGE TREATMENT WITH COMBINED INJURY OF THE THIN AND THICK POUCH
Authors: Boyko V. V. , Peev S. B. , Timchenko M. E. , Borodai V. O. , Sydoriak A. V. , Voskresenska N. M.
Published: June 2024

Abstract. In GU „Institute of general and urgent surgery of V.T. Zayceva of AMNU” from 2014 to 2023 it was treats 42 sufferings with a heavy trauma organs of abdominal region, for 18 patients the method of a multistage treatment (Damage control)was grounded, with brief operative interference on the first stage, that allowed to bring down postoperative lethality on 22,3% and festering-septic complications on 18,1%.