bluuebunny/crossref_metadata_2025 huggingface dataset:
Ammopiptanthus nanus Population Dynamics: Bridging the Gap Between Genetic Variation and Ecological Distribution Patterns
Authors: Liu Jingdian , Wei Mengmeng , Lu Jiayi , Liu Shiqing , Li Xuerong , Wang Xiyong , Wang Jiancheng , Zhang Daoyuan , Lu Ting , Shi Wei
Published: January 2025

Ammopiptanthus nanus, a Tertiary-era endangered plant, is of great scientific value. In this research, we focus on A. nanus population dynamics in an effort to bridge the divide between micro genetic variation and a macroscopic ecological pattern of distribution. The population structure of 129 wild specimens of A. nanus from eight populations was analyzed using EST-SSR molecular markers in this research. The Mantel test and RDA analysis have been used in this research to investigate the factors that influence the genetic diversity of A. nanus. Using 15 pairs of SSR primers, a total of 227 alleles were detected in 129 samples from 8 populations. The mean number of alleles was 17, and the average expected heterozygosity was 0.405. It is shown that wild A. nanus is divided into six individual populations. A. nanus are significantly affected by wind speed in terms of the variation of genetics. It is suggested that a nature conservation area for A. nanus be established as soon as possible, based on our results and the current natural distribution of the species. It is necessary to focus on the issue of pests and diseases while simultaneously preventing the continuation of anthropogenic woodcutting and disaster. Manual seedling collection should be employed in regions where the environment permits. Through making use of manual breeding techniques, this will contribute to the growth of the natural population of A. nanus.
Biophysical Properties of Somatic Cancer Mutations in the S4 Transmembrane Segment of the Human Voltage-Gated Proton Channel hHV1
Authors: Jardin Christophe , Derst Christian , Franzen Arne , Mahorivska Iryna , DeCoursey Thomas E. , Musset Boris , Chaves Gustavo
Published: January 2025

Somatic mutations are common in cancer, with only a few driving the progression of the disease, while most are silent passengers. Some mutations may hinder or even reverse cancer progression. The voltage-gated proton channel (HV1) plays a key role in cellular pH homeostasis and shows increased expression in several malignancies. Inhibiting HV1 in cancer cells reduces invasion, migration, proton extrusion, and pH recovery, impacting tumor progression. Focusing on HVCN1, the gene coding for the human voltage-gated proton channel (hHV1), 197 mutations were identified from three databases: 134 missense mutations, 51 sense mutations, and 12 introducing stop codons. These mutations cluster in two hotspots: the central region of the N-terminus and the region coding for the S4 transmembrane domain, which contains the channel’s voltage sensor. Five somatic mutations within the S4 segment (R205W, R208W, R208Q, G215E, and G215R) were selected for electrophysiological analysis and MD simulations. The findings reveal that while all mutants remain proton-selective, they all exhibit reduced effective charge displacement and proton conduction. The mutations differentially affect hHV1 kinetics, with the most pronounced effects observed in the two Arg-to-Trp substitutions. Mutation of the first voltage-sensing arginine (R1) to tryptophan (R205W) causes proton leakage in the closed state, accelerates channel activation, and diminishes the voltage dependence of gating. Except for R205W, the mutations promote the deactivated channel configuration. Altogether, these data are consistent with impairment of hHV1 function by mutations in the S4 transmembrane segment, potentially affecting pH homeostasis of tumor cells.
Wearable Visual Biofeedback of Vertical Ground Reaction Force Enables More Symmetrical Force Production During Deadlifting and Squatting
Authors: Smith Jacob , Siddicky Safeer Farrukh , Hsiao Hao-Yuan
Published: January 2025

Background/Objectives: Asymmetries in force production, characterized by vertical ground reaction forces (VGRFs), during lower-limb bilateral movements such as deadlifting and squatting, are considered biomechanical risk factors for injury. Real-time biofeedback has been used to modify lower limb force production but typically implements monitors. The purpose of this study was to determine the effect of wearable visual biofeedback (WVBF) on asymmetries in VGRFs and knee joint angles and the rate of perceived exertion (RPE) during deadlift and body-weight squatting (BWS) exercises in recreational powerlifters. Methods: Thirteen healthy young adults between 18–35 years of age performed three tasks: deadlifting for mixed-grip style (MIX), double-overhand style (DO), and BWS. Each task included two conditions: with and without WVBF. A two-way (Condition X Task) mixed model analysis of variance was performed to compare the bilateral asymmetry index of VGRFs, knee angle, and RPE scores. Results: A main effect of the condition (with versus without WVBF) was detected for VGRF symmetry (F (1,12) = 62.785, p < 0.001). WVBF showed decreased VGRF asymmetry compared to no biofeedback. For knee angle, a significant condition X task interaction (F (2,24) = 3.505, p < 0.05) was observed. For RPE, a main effect of the condition was observed (F (1,12) = 8.995, p < 0.05). WVBF showed greater RPE compared to no biofeedback. Conclusions: These results indicated that WVBF could reduce VGRF asymmetry during deadlifting and squatting. In addition, targeting force production symmetry may not directly yield joint angle symmetry and may increase perceived exertion. These results could provide valuable insight into VGRF modulation during deadlifting and squatting exercises in athletic and potentially clinical settings when targeting VGRF symmetry.
Analysis and Visualization of Confounders and Treatment Pathways Leading to Amputation and Non-Amputation in Peripheral Artery Disease Patients Using Sankey Diagrams: Enhancing Explainability
Authors: Korutla Rajashekar , Tedder Douglas , Brogan Kathryn , Milosevic Marko , Wilczek Michael P. , Shehadeh Naim , Shara Nawar , Ross Elsie G. , Amal Saeed
Published: January 2025

Background/Objectives: This study uses Sankey diagrams to analyze treatment pathways in patients with peripheral artery disease (PAD), which is a vascular condition characterized by atherosclerotic occlusion of the arteries, particularly in the lower limbs, affecting up to 14% of the general population. This study focuses on the treatment pathways that lead to amputation versus those that do not, utilizing the STARR dataset and the All of Us dataset. Methods: The study utilized Sankey diagrams to visualize treatment pathways, highlighting the progression from initial treatments to outcomes. Odds ratio analysis was performed to quantify the association between treatment pathways and outcomes. Recognizing potential confounders, analyses were conducted by filtering patients with PAD into subgroups based on these coexisting conditions. Sankey diagrams were then generated for each sub-cohort to visualize treatment pathways. Results: Pathways including antiplatelet and lipid-lowering treatments accounted for 56% of non-amputation cases in the STARR data and 50% in the All of Us data. Amputation pathways frequently included revascularization procedures, representing 15% of amputations in the STARR data and 20% in the All of Us data. Confounder analysis revealed that most amputated PAD patients were over 50 years old and had one or more conditions, such as diabetes, hypertension, or hyperlipidemia. Conclusions: These visualizations provide insights into treatment pathways and their associations with outcomes in PAD patients, highlighting the potential impact of specific treatments on amputation and non-amputation cases. Future work should build on these findings by incorporating predictive models using machine learning techniques to further explore and quantify these relationships.
Perception of Loneliness in Adolescence: Role of Maladaptive Personality Traits and Trauma-Related Symptomatology
Authors: Giordano Fiorenza , Calaresi Danilo , Saladino Valeria , Verrastro Valeria
Published: January 2025

Background/Objectives: Loneliness is a heterogeneous phenomenon, generally defined as an emotional experience based on the perceived distance between an individual’s actual social relationships and those he or she would like to have. Adolescence is particularly vulnerable to loneliness because of the many changes in values, feelings, and emotions that characterize it. Among the aspects that may influence this feeling of discomfort, the literature identifies maladaptive personality and a dysfunctional response to traumatic events. Our study aims to identify the possible role that maladaptive personality traits and post-traumatic stress symptomatology in the form of Post-Traumatic Stress Disorder (PTSD) and Disturbance in Self-Organization (DSO) may play in the perception of loneliness in adolescents: Methods: We identified a mediation model constructed through structural equation modeling (SEM) to test PTSD and DSO post-traumatic stress symptomatology as independent variables and maladaptive personality as a mediator in the relationship between these and perceptions of loneliness in a population of adolescents of both sexes, Italian high school students; Results: Our study identifies the significant role of PTSD and DSO symptomatology in influencing the state of loneliness, both directly and indirectly through maladaptive personality traits, which appear to exert a substantial influence on the perception of loneliness, potentially functioning as mediators in the relationship between the latter and PTSD/DSO symptomatology. Presumably, a maladaptive personality may complicate recovery from adverse and traumatic experiences by preventing the implementation of functional coping strategies and promoting dysfunctional responses. Conclusions: Our findings underscore the importance of researchers and clinicians adequately considering different personality traits and the early identification of post-traumatic stress symptomatology. A focus on adolescents’ communication and interpersonal skills and their ability to respond effectively to stressful and traumatic events may prove useful in identifying more effective strategies for preventing and managing loneliness and related distress in adolescents.
Effects of a Distributed Form of Constraint-Induced Movement Therapy for Clinical Application: The Keys Treatment Protocol
Authors: dos Anjos Sarah , Bowman Mary , Morris David
Published: January 2025

Background/Aim: Currently, there are limited evidence-based protocols for improving upper extremity (UE) motor function after stroke. The Keys protocol, a distributed form of constraint-induced movement therapy (CIMT), delivers CIMT components in fewer hours per day over an extended period, fitting outpatient rehabilitation schedules and third-party payor models. This pilot study aimed to assess the effectiveness of the Keys protocol in enhancing UE capacity and performance poststroke. Methods: Ten adults with chronic stroke (>6 months) participated in an 8-week intervention. The protocol included 22 supervised training sessions (1.5 h each): 4 days/week for 4 weeks, 2 days/week for weeks 5–6, and 1 day/week for weeks 7–8. Participants wore a restraint mitt on the less-affected UE during waking hours and used an adapted transfer package. Outcome measures included the Motor Activity Log (MAL), Wolf Motor Function Test (WMFT), Stroke Impact Scale (SIS), and Zung Depression Scale, assessed pre-treatment, mid-treatment (4 weeks), and posttreatment. Results: Significant improvements were observed in SIS Strength, ADLs/IADLs, Mobility, and Hand Function domains, exceeding MCID thresholds. Memory and Communication domains improved significantly at the 3-month follow-up. WMFT performance times improved, with fewer incomplete tasks. MAL scores for Amount of Use and Quality of Movement increased across all time points. Depressive symptoms significantly decreased posttreatment. Conclusions: The Keys protocol effectively improves UE use, motor function, mood, and quality of life, with the greatest gains observed mid-intervention. These findings support its feasibility and potential for outpatient stroke rehabilitation (ClinicalTrials.gov Registration: NCT05311384).
Impact of Exercise on Tramadol-Conditioned Place Preference
Authors: Amawi Haneen , Hammad Alaa M. , Ibrahim Aseel Abdullah , Alsbih Nosyba , Hall Frank Scott , Alasmari Fawaz , Al-Trad Bahaa
Published: January 2025

Background: Tramadol (TRA) is an opioid that is used to manage moderate to severe pain. Long-term use of TRA can lead to the development of opioid use disorder. Objectives: This study investigates the role of forced exercise in reducing TRA-seeking behavior. Methods: Adult male rats (240–260 g) were divided into five groups; the control group received vehicle injections, the TRA group received TRA (75 mg/kg, i.p) every other day for 8 days, and three TRA–exercise groups were forced to run on a treadmill (60 min/day, 5 days/week) for 2, 4, or 6 weeks prior to conditioning with TRA. A tramadol-conditioned place preference (CPP) procedure assessed TRA reinforcement, after which all rats were euthanized, tissue extracted, and mRNA expression for brain-derived neurotrophic factor (Bdnf) and interleukin 1 beta (Il-1β) determined in hippocampus (Hipp), prefrontal cortex (PFC), and nucleus accumbens (NAc). Results: TRA-seeking behavior was seen in the TRA group and the 6 weeks forced exercise group. By contrast, forced exercise for 2 or 4 weeks attenuated TRA-seeking behavior. This attenuation was associated with a significant increase in Bdnf mRNA expression in the Hipp and NAc, but not the PFC. Additionally, the TRA-induced elevations in Il-1β mRNA expression were reversed by all durations of exercise in Hipp. However, only 2 and 4 weeks, but not 6 weeks, of exercise reduced elevations in PFC and NAc Il-1β expression. Conclusion: Forced exercise for 2 and 4 weeks attenuates TRA-seeking behavior partially through the regulation of Bdnf and Il-1β mRNA expression.
Exploring the Dimensions of Perfectionism in Adolescence: A Multi-Method Study on Mental Health and CBT-Based Psychoeducation
Authors: Chęć Magdalena , Konieczny Krystian , Michałowska Sylwia , Rachubińska Karolina
Published: January 2025

Background: Perfectionism in adolescents can have both adaptive and maladaptive forms, with implications for mental health and school performance. This study aimed to investigate the relationships among perfectionism, mental health factors, and emotional regulation in adolescents and to evaluate the efficacy of psychoeducational interventions. Methods: Two studies were conducted: (1) A cross-sectional study (n = 261) examined the correlations among perfectionism, mental health factors, and emotional regulation. (2) An experimental study (n = 115) evaluated the effects of psychoeducation on perfectionism and healthy habits compared with a control group. The measures included questionnaires on perfectionism, depression, anxiety, stress, and emotional regulation. Results: Study 1 found that maladaptive perfectionism was positively correlated with depression (r = 0.52, p < 0.001), anxiety (r = 0.48, p < 0.001), stress (r = 0.45, p < 0.001), and difficulties in emotional regulation (r = 0.39, p < 0.001). Adaptive perfectionism was negatively correlated with deficits in emotional understanding (r = −0.31, p < 0.05). Study 2 showed that psychoeducational interventions reduced maladaptive perfectionism (mean difference = −5.7, p < 0.05, Cohen’s d = 0.62) and depression levels (mean difference = −3.2, p < 0.05, Cohen’s d = 0.38) but increased stress in the experimental groups. No significant changes were observed in adaptive perfectionism or the anxiety level. Conclusions: These findings highlight the complex relationships among perfectionism, mental health, and emotional regulation in adolescents. Targeted interventions can reduce maladaptive perfectionism and its associated negative effects. Further research is needed on the long-term outcomes and refinement of interventional strategies.
Gustatory-Visual Interaction in Human Brain Cortex: fNIRS Study
Authors: Jezierska Karolina , Cymbaluk-Płoska Aneta , Zaleska Justyna , Podraza Wojciech
Published: January 2025

Background: Many studies, for example, on taste-visual dissonance, have shown that the influence of the visual cortex on taste sensation is enormous. The presented work aims to investigate, using fNIRS, whether a taste stimulus, in this case, the taste of bitter, also causes stimulation of the visual cortex in the fNIRS study. Methods: fNIRS was used to examine 51 participants (204 examinations, 9996 records), collecting signals from the left hemisphere. Differences between the maximum and minimum changes in oxyHb concentrations (ΔoxyHb) for the areas of the brain cortex considered responsible for recording visual and gustatory signals were analyzed. Protocols I, II, III, and IV—activation with distillate water, coffee with lower concentration, reference (no stimulation), and coffee with higher concentration, respectively, were used. Results: We recorded high signals for teste activation on channels covering the gustatory cortex, which confirms the correctness of the choice of research method. As expected, a significant statistical difference was observed between protocols I, II, and IV and reference III (without stimulation). What seems important is the fact that we also received high signals for the channels 45–49, which cover the visual cortex. The statistical analysis shows no differences between protocols I, II, and IV (different taste activation—water, coffee A, and coffee B) for specific channels for analyzing regions of interest. As a result of the analysis of the correlation between the subjective bitterness assessment solutions and the signal ΔoxyHb height, it was observed that a statistically significant correlation, although weak, occurs only for 14 and gustatory channels, only for coffee with a higher concentration. Additionally, the only statistically significant difference between women and men was observed in Protocol I (water), where the ΔoxyHb signal was twice as high in women compared to men. Conclusions: In conclusion, we can clearly state that the senses of sight and taste work closely together. Moreover, this cooperation is not one-sided: while visual activation influences taste perception, interestingly, a taste stimulus can also generate a hemodynamic response, activating the visual cortex.
Postdigital Bystanding: Youth Experiences of Sexual Violence Workshops in Schools in England, Ireland, and Canada
Authors: Ringrose Jessica , Ging Debbie , Mishna Faye , Milne Betsy , Horeck Tanya , Mendes Kaitlynn
Published: January 2025

In this paper, we report on creative- and arts-based sexual violence and bystander intervention workshops we developed and researched in England, Ireland, and Canada, through evaluation surveys, observations, and focus group interviews with nearly 1200 young people (aged 13–18). Whist the young people generally reported benefitting from the intervention, in the context of increasing use of digital technologies amongst youth, we explore the context-specific challenges they faced in learning about and being supported through bystander strategies across a wide range of diverse school spaces. We use the term postdigital bystanding to explicitly explore how teen’s digital networks are often connected to the school-based ‘real life’ peer group, in ways that complicate clear distinctions between online and offline, arguing that these postdigital dynamics have not yet been adequately considered in bystanding interventions. We analyse how the intersectional community, cultural, and identity-specific factors in particular schooling environments shape responses to bystanding in postdigital environments, including how factors of sexism, defensive masculinity, elitism, racism, and a reluctance to report digital issues played out in the responses to the workshops. Finally, following young people’s suggestions, we recommend that schools need to cultivate better safety and support strategies for youth in order to make postdigital bystander interventions more responsive and therefore effective in challenging and preventing sexual violence in society.
Predictors of Young Adult Women’s Psychological Well-Being in Romantic Relationships
Authors: Yöyen Elif , Çalık Süreyya , Güneri Barış Tülay
Published: January 2025

Psychological well-being is the experience of fewer negative emotions, such as feelings of loneliness, depression, and low mood, and more positive emotions, such as taking pride in one’s life, being enthusiastic about one’s life, and having a highly satisfying purpose in life. In other words, it describes an individual who is happy and free from psychopathology. Psychological well-being in romantic relationships is influenced by several factors, such as empathy, relationship stability, and quality of sex life. This study was conducted to examine the relationship between psychological well-being and empathy, quality of sexual life, love, relationship intimacy, and relationship stability among women in romantic relationships. This study included 415 female participants aged 23–45 who had been in a romantic relationship for at least 12 months. Data were collected using the Sociodemographic Data Form, the Psychological Well-Being Scale (PWBS), the Basic Empathy Scale (BES), the Sexual Quality of Life Scale—Women’s Form (SQLS), the Relationship Stability Scale (RSS), the Passionate Love Scale (PLS) and the Romantic Relationship Closeness Scale (RRCS). Independent group t-test, one-way analysis of variance (ANOVA), Pearson correlation analysis, and regression analysis were used to analyse the data. The analyses found that the variables that predicted psychological well-being were the relationship satisfaction sub-dimension of the relationship stability scale, quality of sexual life, empathy, and having children. In addition, correlational analysis revealed that empathy, sexual quality of life, intimacy in romantic relationships, relationship satisfaction, and relationship attachment were significantly positively correlated with psychological well-being. In terms of demographic information, it was found that scores for evaluating options in the relationship increased as education level increased; scores for investing in the relationship increased as education level decreased; passionate love was more common among working women; having children increased psychological well-being but decreased intimacy in romantic relationships; and quality of sexual life increased as seriousness in the relationship increased. The results of this study may be useful to psychologists and psychiatrists in their studies of female clients, to sociologists and public health specialists in their studies of women, and to policy makers in determining public health policies.
Experiencing Traumatic Violence: An Interpretative Phenomenological Analysis of One Man’s Lived Experience of a Violent Attack Involving a Knife
Authors: Partington Zoe , Walsh R. Stephen , Labhardt Danielle
Published: January 2025

A review of the violent knife crime literature suggests that the experiential perspective is one which has not been addressed in academic study. The research presented hereafter aims to address this literary gap and generate transferable knowledge relevant to the lived experience of violent knife crime. The experiential study of the single case within psychological research involves detailed examination of a particular event. Participant ‘J’ is the survivor of an extremely violent attack, involving the use of a knife, in his own home. J’s experience was analysed using Interpretative Phenomenological Analysis with reference to elements of the lifeworld: temporality, spatiality, intersubjectivity, and embodiment. Three themes were identified: 1. switching from past to present tense when relaying traumatic experience; 2. The presence of redemption sequences; and 3. making sense as a temporal process, which included an additional two subthemes—‘The long journey’ and ‘Seeking belongingness’. This case emphasises that the traumatic event is conceptualised as one part of a longer journey towards recovery, and that recovery itself is central to the experience of violent knife crime. Finally, the need to understand recovery as temporal process highlights the need to provide victims with appropriate support in order to avoid negative outcomes.
The Transformative Power of Embodied Behaviour: Influencing Tourists’ Experience in the Guangzhou Marathon as a Mass Participant Sports Event
Authors: Xu Xin , Dai Guangquan
Published: January 2025

Mass-participation sports events (MPSEs) are of significant value to the fields of sports, culture, and tourism. MPSEs have witnessed a remarkable surge in popularity, which has led to a complex interplay of factors influencing participants’ overall experience, making it crucial to understand the role of embodied behaviour. However, the existing literature is deficient in terms of providing substantial evidence, particularly with regard to the growing significance of experience planning as a core aspect of event design. This research employed the Guangzhou Marathon, one of the most renowned MPSEs in China, as a case study. The objective of this research is to investigate and extend the knowledge of the embodied behaviour of MPSE tourists through the mixed method of a questionnaire survey together with interviews. Furthermore, this research aimed to explore the antecedents and consequences of the embodied experience formation process. The findings demonstrated the pivotal role of the embodied experience in shaping tourist perceptions and subsequent intentions. Specifically, this research suggested that tourist behaviour with experience and attachment influenced the perceived value and cost of participation willingness through moderating and mediating effects. The findings contribute to the existing knowledge on sports tourism and behavioural studies and provide sustainable event management strategies.
Self-Identified Employment Challenges for Young Adults with a Cleft Lip and Palate: A Qualitative Exploration
Authors: Rani Haslina , Mohd Ibrahim Hasherah , Mohamed Noor Shafie Nurshazwanie Amira , Mohamed Suziyani , Shaari Azianura Hani , Nor Murshida Marizan , Mohd-Dom Tuti Ningseh
Published: January 2025

As individuals with a cleft lip and palate (CLP) transition into adulthood, they face unique employment challenges related to income, job stability, and fewer career options. This study explored these challenges through two focus group discussions with 19 participants (aged 21–38), primarily women, to understand their employment experiences. Thematic analysis revealed the following three main themes: (1) physical factors, (2) psychosocial factors, and (3) overcoming employment challenges, with nine sub-themes including speech, hearing, appearance, health, childhood experiences, societal expectations, lack of self-confidence, communication improvement, and self-esteem building. The findings highlighted that physical and psychosocial factors significantly shape employment outcomes for CLP individuals. Difficulties with speech often hinder professional communication, while appearance concerns can reduce confidence in interviews and workplaces. To address these issues, the participants used strategies like targeted speech therapy and self-esteem building, which helped improve their communication and resilience. This study emphasises the need for targeted interventions such as specialised career counselling, access to assistive technologies, and inclusive workplace policies to support CLP individuals in overcoming employment barriers and achieving stable careers.
Stakeholders’ Roles in Evolutionizing Education: An Evolutionary-Based Toolkit Surrounding Elementary Education
Authors: Gruskin Kathryne , Griffin Mariah , Bansal Sonaskshi , Dickinson-Frevola Stephanie , Dykeman Ashlee , Groce-Volinski Desiree , Henriquez Keydy , Kardas Maya , McCarthy Aileen , Shetty Aman , Staccio Brandon , Geher Glenn , Eisenberg Ethan
Published: January 2025

There is a rapidly growing body of research in the field of evolutionary educational psychology that examines children’s evolved motivational and educational inclinations as they relate to modern learning and schooling. It is generally agreed that schools are inherently mismatched with how children of our species evolved to learn, thereby contributing to difficulty learning and associated adverse schooling outcomes. Many researchers argue that, by making small changes to schools that help to better align instructional methods and childhood as a whole with our species’ evolved learning mechanisms, we can lessen the negative impacts from evolutionary mismatch and create better outcomes for modern students. In order to create effective change, there must be collaborative work done by parents, teachers, and school administrators. This paper delineates the roles of these stakeholders in elementary education with respect to creating more evolutionarily relevant systems. A research-based toolkit is proposed to guide these stakeholders in evolutionizing the elementary education system.
Investigation into the Early Cracking Behavior of High-Geothermal Tunnel Lining Concrete Based on Thermal–Mechanical Coupling Model
Authors: Xie Si , Zhao Dan , Yi Peng , Chen Qian , Liu Wei
Published: January 2025

As a typical extreme environment, a high-geothermal environment poses severe challenges to tunnel construction in western China. In this paper, a thermal–mechanical coupling model was formulated to evaluate the cracking behavior of lining under high-geothermal conditions, considering the early property evolution of concrete. This was further validated by field monitoring and analyzed by adjusting the relevant parameters. Results indicate that the higher cracking risk occurred on the external surface of the lining sidewall after 24 h of casting. With the increase in surrounding rock temperature, the duration of cracking risk in the lining was extended. When the surrounding rock temperature exceeded 68.7 °C, thermal insulation measures were required for the lining structure. Notably, superior thermal insulation was achieved by applying a sandwich structure of rigid polyurethane materials with a thickness of 20–60 mm. In terms of curing conditions, adopting formwork with a larger heat convection coefficient was conducive to reducing the cracking risk of the tunnel lining, with an appropriate removal time of 48 h. This work provides insights into the thermal–mechanical behavior of lining concrete, thereby mitigating its early cracking in a high-geothermal environment.
Effect of Different Mechanical Fans on Virus Particle Transport: A Review
Authors: Han Xiaofei , Mahyuddin Norhayati , Qin Mingyuan , Wang Puyi , Zhang Changchang , Wei Yixuan , Pan Song
Published: January 2025

In recent years, repeated outbreaks of airborne viruses have normalized human coexistence with these viruses. The complex turbulence and vortices generated by different fan types and operation modes affect virus removal effectiveness. This paper reviews the potential impact and actual effectiveness of different fans in mitigating indoor virus transmission, highlighting their advantages and limitations. Downward rotating ceiling fans can rapidly dilute virus concentration (21–87%) in the breathing zone due to jet cores, with efficiency depending on rotational speed and particle diameter. However, the reprocessing problems of large particles being deposited on surfaces, and small particles settling and rebounding into the air remain unresolved. Upward-rotating ceiling fans do not contribute to indoor virus removal. Exhaust fans generate a negative-pressure environment, which helps expel viruses quickly. But improper vortex zones can increase virus retention time 16–40 times. Air-apply fans effectively dilute and transport viruses only when delivering airflow exceeding 0.5 m/s directly into the breathing zone. Additionally, combined fan strategies remain underexplored, despite potential benefits. This review underscores the need for standardized definitions of particle removal effectiveness and calls for further research on how climatic conditions and thermal comfort influence fan-based interventions.
Advancements in Surface Coatings and Inspection Technologies for Extending the Service Life of Concrete Structures in Marine Environments: A Critical Review
Authors: Lee Taehwi , Kim Dongchan , Cho Sanghwan , Kim Min Ook
Published: January 2025

Concrete structures in marine environments are subjected to severe conditions that significantly compromise their durability and service life. Exposure to chloride penetration, sulfate attack, and physical erosion accelerates deterioration, leading to extensive maintenance requirements and high associated costs. To address these challenges, significant advancements in surface coatings and inspection technologies have been developed to enhance the longevity of concrete structures. This review examines recent progress in protective surface coatings that mitigate environmental damage and explores state-of-the-art inspection techniques for assessing structural integrity. By providing a comprehensive analysis of innovative materials, coating applications, and non-destructive evaluation methods, this paper aims to equip researchers and industry professionals with effective strategies for preserving concrete infrastructure in marine environments.
Charring Properties of Korean Larch Structural Glue-Laminated Timber Beams Based on Cross-Sectional Area Ratios
Authors: Choi Yunjeong , Baik Kwonhyuk , An Jaehong , Kim Byoungil
Published: January 2025

Carbon emissions accelerate global warming and climate change, prompting the global development of strategies for carbon reduction. Wood, with its excellent carbon storage capacity, is a sustainable and environmentally friendly material. One cubic meter of timber can absorb 1 t of carbon dioxide and store 250 kg of carbon. This study aimed to conduct fire resistance tests on structural glue-laminated timber beams made from Korean larch (Larix kaempferi) and analyze their char properties. The specimens were fabricated with different cross-sectional shapes and areas and underwent load-bearing fire resistance tests. The results were analyzed in terms of char depth, char rate, and changes in char thickness based on the aspect ratio of the beams. In the smaller specimens, the char properties were influenced more by the width than by the length of the beam. Additionally, at a constant cross-sectional area, charring was deeper when the width was shorter than the height. The specimens did not exhibit significant differences in displacement behavior, with all specimens displaying displacements below the maximum permissible value, indicating suitable fire resistance. The findings of this study provide a foundation for research and development of fire resistance design standards for wooden structures utilizing Korean timber.
Multi-Point Optical Flow Cable Force Measurement Method Based on Euler Motion Magnification
Authors: Wu Jinzhi , Yan Bingyi , Xue Yu , Qin Jie , You Deqing , Sun Guojun
Published: January 2025

This study introduces a multi-point optical flow cable force measurement method based on Euler motion amplification to address challenges in accurately measuring cable displacement under small displacement conditions and mitigating background interference in complex environments. The proposed method combines phase-based magnification with an optical flow method to enhance small displacement features and improve SNR (signal-to-noise ratio) in cable displacement tracking. By leveraging magnified motion data and integrating auxiliary feature points, the approach compensates for equipment-induced vibrations and background noise, allowing for precise cable displacement measurement and the identification of vibration modes. The methodology was validated using a scaled model of a cable net structure. The results demonstrate the method’s effectiveness, achieving a significantly higher SNR (e.g., from 7.5 dB to 22.24 dB) compared to traditional optical flow techniques. Vibration frequency errors were reduced from 6.2% to 1.5%, and cable force errors decreased from 11.38% to 3.13%. The multi-point optical flow cable force measurement method based on Euler motion magnification provides a practical and reliable solution for non-contact cable force measurement, offering potential applications in structural health monitoring and the maintenance of bridges and high-altitude structures.
Response of Daytime Changes in Temperature and Humidity to Three-Dimensional Urban Morphology in Subtropical Residential Districts
Authors: Huang Ziyi , Luo Tao , Liu Jiemin , Qiu Yao
Published: January 2025

The combination of global climate change and the urban heat island effect has given rise to a deterioration in the livability of residential districts within cities, posing challenges to enhancing the health quality of urban environments. Meanwhile, the intensification of daytime changes in temperature and humidity in residential districts has rendered the sensory representation of the urban heat island effect more pronounced. This study selects the residential districts in Fuzhou City as the research case area, which have witnessed a discernible warming trend in recent years, and acquires temperature and humidity parameter data at three time periods (early morning, noon, and evening) to represent the daytime temperature and humidity change phase. Through aerial photography and field research, three types of spatial morphological indicators (buildings I, vegetation II, and the combination of buildings and vegetation II) of residential districts are quantified to represent the three-dimensional spatial form of the case study area. The analysis results show the following: ➀ Residential districts experience two phases of daytime changes in temperature and humidity: a warming and drying phase (WDP) in the morning and a cooling and humidifying phase (CHP) in the afternoon. The characteristics of changes in temperature and humidity show a spatial correlation with each other. ➁ The impact of urban three-dimensional morphology on changes in temperature and humidity in WDP is minor, whereas, in CHP, it is influenced by Class II and Class III indicators. The two types of urban morphology exert a synergistic regulatory effect on changes in temperature and humidity. ➂ Vegetation has a significant regulatory effect on temperature and humidity variations in residential areas through changes in its three-dimensional form. Enlarging the area of individual trees while reducing their canopy volume can restrain the warming and dehumidification of residential districts and promote cooling and humidification. In contrast to only planting trees, a vegetation configuration combining trees, shrubs, and grass can bring a more obvious cooling effect to residential districts. The research results can provide a reference for urban planners in the planning and design of residential areas as well as the optimization and improvement of urban living environments.
Model Testing for Bending Performance on Fragile Cross-Section of Square Hollow Steel-Reinforced Concrete Column
Authors: Li Hulin , Zhou Yang , Geng Shenglin , Qin Haijiang , Wang Xiong , Li Jinpeng
Published: January 2025

This study researches the bending and shear performance of the fragile cross-section of square hollow steel-reinforced concrete columns using experiments, numerical analysis, and theoretical investigation. First, three tests of square hollow steel-reinforced concrete column (HSrCC) specimens considering different sectional sizes and grouting conditions were conducted. The bearing capacity and load transfer mechanisms under bending and shear loading were experimentally compared. Second, a numerical model was established based on the experimental results, and then parametric studies were performed on the bearing capacity and deformation of the structure. Last, a peak load calculation formula was derived in this study considering thickness and strength for a 400 × 400 square HSrCC. Based on the experimental results, the failure process of the specimen can be divided into four steps. Grouting increases stiffness at the front part of the specimen but induces significant damage at the rear compared to the no-grouting case, with the maximum strain increasing by 25%. Increasing the cross-sectional area of the concrete short column effectively improves the overall performance, with the maximum tensile strain of the concrete short column being reduced by approximately 1.2 times. Under the given sectional dimensions, parametric analysis suggests that the optimal square hollow steel thickness and steel strength range from 14 mm to 16 mm and from Q355 to Q420, respectively. The proposed peak load calculation formula demonstrates a discrepancy of less than 5.06% when compared with the numerical model results. These findings provide valuable references for the design of square hollow steel-reinforced concrete columns.
Predicting Response to Treatment and Survival in Advanced Ovarian Cancer Using Machine Learning and Radiomics: A Systematic Review
Authors: Piedimonte Sabrina , Mohamed Mariam , Rosa Gabriela , Gerstl Brigit , Vicus Danielle
Published: January 2025

Background and Objective: Machine learning and radiomics (ML/RM) are gaining interest in ovarian cancer (OC) but only a few studies have used these methods to predict treatment response. The objective of this study was to review the literature on the applications of ML/RM in OC assessments, specifically focusing on studies describing algorithms to predict treatment response and survival. Methods: This is a systematic review of the published literature from January 1985 to December 2023 on the use of ML/RM in OC An extensive search of electronic library databases was conducted. Two independent reviewers screened the articles initially by title then by full text. Quality was assessed using the MINORS criteria. p-values were generated using the Pearson’s Chi-squared (x2) test to compare the performances of ML/RM models with traditional statistics. Results: Of the 5576 screened articles, 225 studies were included. Between 2021 and 2023, 49 studies were published, highlighting the rapidly growing interest in ML/RM. Median-quality scores using the MINORS scale were similar between studies published between 1985–2021 and 2021–2023 (both 8). Neural Networks (22.6%) and LASSO (15.3%) were the most common ML/RM algorithms in OC. Among these studies, 13 focused specifically on prediction of treatment response using radiomics. A total of 5113 patients were analyzed. The most common algorithms were Random Forest (4/13) followed by Neural Networks (3/13) and Support Vectors (3/13). Radiomic analysis was used to predict response to neoadjuvant chemotherapy in seven studies, with a median AUC of 0.77 (range 0.72–0.93), while the median AUC was 0.82 (range 0.77–0.89) in the six studies assessing the prediction of optimal or complete cytoreduction. Median model accuracy reported in 7/13 studies was 73% (range 66–98%). Additionally, four studies investigated the use of ML/RM for survival prediction for OC. The XGBoost model had 80.9% accuracy in predicting 5-year survival compared to linear regression, which achieved 79% accuracy. The Random Forest model has 93.7% accuracy in predicting 12-month progression-free survival, compared to 82% for linear regression. Conclusions: In conclusion, we found that the use of ML/RM algorithms is becoming a more frequent method to predict responses to treatment of OC. These models should be validated in a prospective multicenter trial prior to integration into clinical use.
Recent Advances in Congo Red Degradation by TiO2-Based Photocatalysts Under Visible Light
Authors: Quintanilla-Villanueva Gabriela Elizabeth , Sicardi-Segade Analía , Luna-Moreno Donato , Núñez-Salas Raisa Estefanía , Villarreal-Chiu Juan Francisco , Rodríguez-Delgado Melissa Marlene
Published: January 2025

Congo Red is a complex aromatic azo dye whose metabolites can be toxic due to their carcinogenicity, mutagenicity, and various associated toxic effects on flora, fauna, and humans. Different technologies have been employed to degrade this dye, including biodegradation, radiation-based degradation, and chemical degradation with catalysts and photocatalysis. Among these, the use of TiO2-based materials combined with photocatalysis has proven to be an effective technology for its degradation. However, the wide bandgap of TiO2 limits its efficiency under visible light, prompting the need for modifications such as doping with metals, metalloids, and organic compounds. These modifications enhance its photocatalytic performance under visible light, achieving degradation efficiencies of up to 100% under optimal conditions. This article explores recent advances (from 2020 to the present) in the degradation of Congo Red using TiO2-based photocatalysts under visible light, focusing on their characteristics, synthesis methods, and degradation efficiencies. Additionally, it compares the TiO2-based photocatalysis with visible light to other available technologies, emphasizing its potential as a sustainable and efficient approach while addressing the importance of monitoring degradation byproducts to prevent the generation of equally or more toxic compounds.
Construction of S-Type PDI/BiOBr Heterojunctions and Their Photocatalytic Activity
Authors: Wang Xin-Qing , Sun Yu , Liu Rui-Hong , Li Fa-Tang
Published: January 2025

Constructing an S-type heterojunction to promote photogenerated carrier separation is a valid method to ameliorate this problem. In this work, self-assembled perylenetetracarboxylic diimide (PDI) was modified on the surface of two-dimensional (2D) BiOBr nanosheets using a continuous ion layer adsorption method. To explore its microstructure, photoelectric properties, and other characteristics, the electron transport channel constructed between self-assembled PDI and BiOBr hinders photogenerated electron-hole recombination. Under visible light irradiation, when the rhodamine B (RhB) was 50 mg/L, the removal rate over 1/3 PDI/BiOBr reached 98% in 60 min, and the rate constant was 15.9 times that over self-assembled PDI and 13 times that over BiOBr. In degrading methyl orange (MO), the removal rate over 1/3 PDI/BiOBr was 65.8% in 60 min, and the rate constant was 5.7 times that over self-assembled PDI and 3.4 times over BiOBr. After the ESR test, O2− is proved to be the main active species in the reaction.
Photocatalytic Nanomaterials for the Abatement of Microorganisms
Authors: De Pasquale Ilaria , Comparelli Roberto
Published: January 2025

The global spread of pathogenic microorganisms, including bacteria, viruses, and fungi, poses a serious threat to public health and the global economy, as evidenced by the severe and widespread impact of the COVID-19 pandemic [...]