bluuebunny/crossref_metadata_2025 huggingface dataset:
Early blood pressure drop exacerbates renal function deterioration and mortality in ICU patients with liver failure
Authors: Guo Rubing , Tong Jingjing , Ma Liang , Wei Lianhua , Cao Yongtong , Zhao Wei
Published: January 2024

Background: The relationship between early blood pressure drop and worsening renal function (WRF) in this patient population is currently unknown but has significant clinical importance. The aim of this study is to investigate the association between early blood pressure drop and WRF in intensive care unit (ICU) patients with liver failure and to evaluate their clinical outcomes, which may improve patient prognosis and clinical management strategies.
Method: This retrospective study utilized data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) version 2.2 database. The study included ICU patients with liver failure who met specific inclusion criteria. Descriptive statistics, analysis of variance (ANOVA), the Kruskal-Wallis test, and the chi-square test were used for the analysis. Multivariate linear regression models were used to assess the determinants of blood pressure drop. Cox proportional hazards and generalized additive models were used to evaluatethe relationship between blood pressure drop, WRF, and 60-day in-hospital mortality. Subgroup analyses and log-rank tests were performed.
Results: Peak systolic blood pressure (SBP) drop was independently associated with a higher risk of WRF (HR: 1.08 per 10 mmHg SBP drop; P < 0.001) and 60-day in-hospital death (HR: 1.14 per 10 mm Hg SBP drop; P <0.001), even after adjusting for potential confounders including baseline SBP. Patients experiencing a peak blood pressure drop above the median and those developing WRF faced a heightened risk of 60-day in-hospital mortality; however, the P-value for interaction was >0.05. The independent risk relationship observed between peak diastolic blood pressure (DBP) and mean arterial pressure (MAP) drop, and the occurrence of WRF and 60-day in-hospital mortality, was similar to that of the peak SBP drop.
Conclusions: In ICU patients with liver failure, a significant early drop in blood pressure was associated with a higher incidence of WRF, increased risk of 60-day in-hospital mortality, and a poorer prognosis.
Comparative analysis of the RVA VP7 and VP4 antigenic epitopes circulating in Iran and the Rotarix and RotaTeq vaccines
Authors: Fallah Tina , Ghanaie Roxana Mansour , Karimi Abdollah , Zahraei Seyed Mohsen , Mahmoudi Sussan , Alebouyeh Masoud
Published: January 2024

Background Group A rotavirus is a leading cause of diarrheal disease, with its prevalence remaining high in low- and middle-income countries. In this study, circulating lineages of VP4 and VP7 proteins of human RVA isolates from children under 5 years of age were analyzed and their cytotoxic T cell and antigenic epitopes were compared to the RotaTeq and Rotarix vaccine strains.
Methods Viral RNA was extracted from 51 positive samples and amplified using specific primers. Sequencing was performed and multiple sequence alignments were done in MEGA and phylogenetic trees were constructed. Similarity of VP7 and VP4 amino acids with the vaccine stains and structural analysis were performed using the UCSF Chimera-Molecular Modeling System.
Results The Iranian strains clustered in the G1/II, G2/IV, G3/I, G4/I, G9/III, P[8]/III, P[4]/IV, and P[6]/I lineages. Comparative analysis of VP7 antigenic epitopes showed that G1/II strains are completely conserved, but G2/IV, G3/I, G4/I, G6, G9/III strains contained 2, 3-5, 2, 4 and 9 amino acids substitutions, respectively. P[8]/III genotypes differed by 3 amino acids, while P[6]/I genotypes had the most substitutions. CTL epitopes were completely conserved in G3/I strains, but other genotypes differed by 1-4 amino acids in comparison to the vaccine strains.
Conclusions Considering the diversity of circulating RVA genotypes and the observed mutations in the neutralizing and CTL epitopes, immune escape by some of the strains is likely in Iran. This finding underscores the importance of evaluating the effect of rotavirus vaccines on local genotypes and related lineages before implementing the vaccination program.
Study on the mechanism of zinc finger proteins ROCK1 and DMD in zinc-mediated cognitive impairment caused by aluminum exposure
Authors: Shang Nan , Li Xianlin , Zhang Lan , Wang ShanShan , He Chanting , Zhang Ling , Niu Qiao , Zheng Xiaojun
Published: January 2024

Background: Aluminum (Al) exposure was implicated in neurodegenerative diseases and cognitive impairment, yet the involvement of zinc (Zn) and its mechanism in Al-induced mild cognitive impairment (MCI) remains poorly understood.
Objective: Exploring the role of Zn in Al-induced cognitive impairment and its potential mechanisms.
Methods:
Montreal Cognitive Assessment (MoCA) test scores, and serum Al, Zn from Al industry workers were collected. A mediation analysis was performed to evaluate the role of serum Zn among serum Al and MoCA test scores. Subsequently, an Al-exposure study was conducted on a rat model categorized into control, low, medium, and high dose groups. After a Morris Water Maze test and detection of Al, Zn content in the hippocampus, integrated transcriptomic and proteomic analyses between the control group and the high-dose group were performed to identify the differentially expressed genes (DEPs), proteins (DEPs), and pathways. To corroborate these findings, quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting (WB) were selected to identify the genes and proteins results.
Results:
Zn overall mediates the relationship between serum Al and cognitive function (mediation effect 17.82%, Effect value = -0.0351). In the Al-exposed rat model, 734 DEGs, 18 miRNAs, 35 lncRNAs, 64 circRNAs, and 113 DEPs were identified between the high-dose group and the control group. Among them, ROCK1, DMD, and other 4 DEPs were identified as related to Zinc finger proteins (ZNF). Co-enrichment analyses of the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) linked these changes to the RHOA/ROCK1 signaling axis. ZNF-related proteins Rock1, DMD, and DHX57 in the high-dose group were downregulated (p = 0.006, 0.003, 0.04), and the expression of Myl9, Rhoa, miR431, and miR182 was also downregulated (p = 0.003, 0.032, 0.032 and 0.046). These findings also show correlations between Al, Zn levels in the hippocampus, water maze performance and expressions of Myl9, Rhoa, miR431, miR182, DMD, ROCK1, and DHX57, with both negative and positive associations.
Conclusion: Based on the results, we determined that Zn was involved in Al-induced MCI in Al workers and Al-exposed rat models. Al exposure and interaction with Zn could trigger the downregulation of ZNF of ROCK1, DMD, and DHX57. miR431, miR182 regulate RHOA/ROCK1 was one of the Zn-involved pathways in Al-induced cognitive impairment.
A Black Phosphorus Nanosheet-based RNA Delivery System for Prostate Cancer Therapy by Increasing the Expression Level of Tumor Suppressor Gene PTEN via CeRNA Mechanism
Authors: Su Shunye , Liu Leyi , Fu Qingfeng , Ma Minghao , Yang Na , Pan Ting , Geng Shengyong , Yu Xue-Feng , Zhu Jianqiang
Published: January 2024

Background
Prostate cancer (PCa) has a high incidence in men worldwide, and almost all PCa patients progress to the androgen-independent stage which lacks effective treatment measures. PTENP1, a long non-coding RNA, has been shown to suppress tumor growth through the rescuing of PTEN expression via a competitive endogenous RNA (ceRNA) mechanism. However, PTENP1 was limited to be applied in the treatment of PCa for the reason of rapid enzymatic degradation, poor intracellular uptake, and excessively long base sequence to be synthesized. Considering the unique advantages of artificial nanomaterials in drug loading and transport, black phosphorus (BP) nanosheet was employed as a gene-drug carrier in this study.
Results
The sequence of PTENP1 was adopted as a template which was randomly divided into four segments with a length of about 1000 nucleotide bases to synthesize four different RNA fragments as gene drugs, and loaded onto polyethyleneimine (PEI)-modified BP nanosheets to construct BP-PEI@RNA delivery platforms. The RNAs could be effectively delivered into PC3 cells by BP-PEI nanosheets and elevating PTEN expression by competitive binding microRNAs (miRNAs) which target PTEN mRNA, ultimately exerting anti-tumor effects.
Conclusions
Therefore, this study demonstrated that BP-PEI@RNAs is a promising gene therapeutic platform for PCa treatment.
RETRACTED: Antibacterial Effects of Silver Diamine Fluoride, Potassium Iodide and Nanosilver Fluoride on Dual-species Biofilm
Authors: Karaduran Büşra , Çelik Sibel , Üçüncü Merve Yıldırım , Topçuoğlu Nursen , Gök Mehmet Koray , Koruyucu Mine
Published: January 2024

The authors have requested that this preprint be removed from Research Square.
Towards Micro-vortices Generated by Liquid Water’s Structural Heterogeneity
Authors: Tozzi Arturo
Published: January 2024

Turbulence is a widespread phenomenon detectable in physical and biological systems. Examining a theoretical model of liquid water flowing in a cylinder at different Raleigh numbers, we propose a novel approach to elucidate the first stages of turbulent flows. The weakly bonded molecular assemblies of liquid distilled water form a fluctuating branched polymer in which every micro-cluster displays different density. Against the common view of liquid water as an incompressible and continuous fluid, we consider it as a non-homogeneous, compressible medium characterised by density differences. We suggest that the occurrence of transient local aggregates in liquid water could produce the vortices and eddies that are the hallmarks of turbulence. As in a two-fluid model, lighter fluid interacts with heavier fluid as if one of the two were an obstacle. Micro-assemblies of such obstacles might justify the presence of micro-vortices and hence of turbulence. We quantify the local changes in velocity, diameter and density required to engender obstacles to the average flow. Then, we explain how these microstructures, equipped with different Raleigh numbers and characterized by high percolation index, could generate boundary layers that contribute to micro-vortices production. We explore the theoretical possibility that three-dimensional turbulence might originate from micro-vortices, contrary to the common view that three-dimensional turbulence is caused by energy cascades from larger to smaller vortices. We conclude that the genesis of turbulence cannot be assessed in terms of collective phenomena, rather is sustained, among many other factors, by the underrated microscopic inhomogeneities of fluids like liquid water.
Comparison of post-COVID-19 symptoms in patients infected with the SARS-CoV- 2 variants delta and omicron - results of the Cross-Sectoral Platform of the German National Pandemic Cohort Network (NAPKON-SUEP)
Authors: Hopff Sina M. , Appel Katharina S. , Miljukov Olga , Schneider Johannes , Addo Marylyn M. , Bals Robert , Bercker Sven , Blaschke Sabine , Bröhl Isabel , Büchner Nikolaus , Dashti Hiwa , Erber Johanna , Friedrichs Anette , Geisler Ramsia , Göpel Siri , Hagen Marina , Hanses Frank , Jensen Björn-Erik Ole , Keul Maria , Krawczyk Adalbert , Lorenz-Depiereux Bettina , Meybohm Patrick , Milovanovic Milena , Mitrov Lazar , Nürnberger Carolin , Obst Wilfried , Römmele Christoph , Schäfer Christian , Scheer Christian , Scherer Margarete , Schmidt Julia , Seibel Kristina , Sikdar Shimita , Tebbe Johannes Josef , Tepasse Phil-Robin , Thelen Philipp , Vehreschild Maria J.G.T. , Weismantel Christina , Vehreschild J. Janne
Published: January 2024

Purpose
The influence of new SARS-CoV-2 variants on the post-COVID-19 condition (PCC) remains unanswered. Therefore, we examined the prevalence and predictors of PCC-related symptoms in patients infected with the SARS-CoV-2 variants delta or omicron.
Methods
We compared prevalences and risk factors of acute and PCC-related symptoms three months after primary infection (3MFU) between delta- and omicron-infected patients from the Cross-Sectoral Platform of the German National Pandemic Cohort Network. Health-related quality of life (HrQoL) was determined by the EQ-5D-5L index score and trend groups were calculated to describe changes of HrQoL between different time points.
Results
We considered 758 patients for our analysis (delta: n = 341; omicron: n = 417). Compared with omicron patients, delta patients had a similar prevalence of PCC at the 3MFU (p = 0.354), whereby fatigue occurred most frequently (n = 256, 34%). HrQoL was comparable between the groups with the lowest EQ-5D-5L index score (0.75, 95%-CI 0.73-0.78) at disease onset. While most patients (69%, n = 348) never showed a declined HrQoL, it deteriorated substantially in 37 patients (7%) from the acute phase to the 3MFU of which 27 were infected with omicron.
Conclusion
With quality-controlled data from a multicenter cohort, we showed that PCC is an equally common challenge for patients infected with the SARS-CoV-2 variants delta and omicron at least for the German population. Developing the EQ-5D-5L index score trend groups showed that over two thirds of patients did not experience any restrictions in their HrQoL due to or after the SARS-CoV-2 infection at the 3MFU.
The cohort is registered at ClinicalTrials.gov since February 24, 2021 (Identifier: NCT04768998).
CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci
Authors: Shao Xiaojian , Fur Sophie Le , Cheung Warren , Belot Marie-Pierre , Perge Kevin , Bouhours-Nouet Natacha , Bensignor Candace , Levaillant Lucie , Ge Bing , Kwan Tony , Lathrop Mark , Pastinen Tomi , Bougnères Pierre
Published: January 2024

Background:
Chronic hyperglycemia is a major risk factor for glomerular or retinal microangiopathy and cardiovascular complications of type 1 diabetes (T1D). At the interface of genetics and environment, dynamic epigenetic changes associated with hyperglycemia may unravel some of the mechanisms contributing to these T1D complications.
Methods
Blood samples were collected from 112 young patients at T1D diagnosis and 3 years later in average. Whole genome-wide bisulfite sequencing using MethylC-Seq was used to measure blood DNA methylation changes of about 28 million CpGs at single base resolution over this time. Chronic hyperglycemia was estimated every 3–4 months by HbA1c measurement. Proportion tests determined the significant longitudinal methylation differences. Linear regressions with adjustment to age, sex, treatment duration, blood proportions and batch effects were employed to characterize the relationships between the dynamic changes of DNA methylation and average HbA1c levels.
Results
We identified that longitudinal DNA methylation changes at 815 CpGs (p-value < 1e-4) were associated with average HbA1c. Most of them (> 98%) were located outside of the promoter regions and were enriched in CpG island shores and multiple immune cell type specific accessible chromatin regions. Among the 36 more significant associated loci (p-value < 5e-6), 16 were harbouring genes or non-coding sequences involved in angiogenesis regulation, glomerular and retinal vascularization or development, or coronary disease.
Conclusion
Our findings support the identification of new genomic sites where CpG methylation associated with hyperglycemia may contribute to long-term complications of T1D, shedding light on potential mechanisms for further exploration.
Reinforcement Learning for Optimized Information Retrieval in LLaMA
Authors: Tu Chien-Hung , Hsu Hsien-Jung , Chen Shih-Wen
Published: January 2024

This study introduces a new approach to enhance information retrieval accuracy in Large Language Models (LLMs) by integrating a specially designed reinforcement learning algorithm into the LLaMA model. The research focuses on developing and implementing an algorithm that dynamically adapts the model's response strategies to user queries, based on a combination of dynamical systems theory and relativistic physics. Empirical results demonstrate that the Optimized LLaMA model exhibits significant improvements in accuracy, relevance, and coherence across various information retrieval tasks compared to the Baseline LLaMA. This advancement not only showcases the potential of reinforcement learning in the realm of natural language processing but also marks a considerable step forward in the development of AI systems capable of nuanced language understanding and decision-making. The study's findings have profound implications for the future of AI research, particularly in enhancing the practical applicability of LLMs in complex, real-world scenarios, and set a new benchmark for the integration of machine learning techniques in language models.
Women's empowerment and uptake of skilled delivery healthcare services in Bangladesh: Evidence from nationally representative survey
Authors: Alam Md Badsha , Khanam Shimlin Jahan , Kabir Md Awal , Chowdhury Atika Rahman , Hassen Md Tahir , Das Susmita , Khan Md Nuruzzaman
Published: January 2024

While the importance of women's empowerment in enhancing access to healthcare services is widely acknowledged, there is limited evidence on the link between women's empowerment and the utilization of skilled healthcare services during delivery. Drawing from data on 4543 women from the 2017/18 Bangladesh Demographic and Health Survey, we explored this association. The outcome variable considered was the uptake of skilled delivery healthcare services, and the major explanatory variable was the composite index of women’s empowerment, along with indicators of women’s empowerment. A multilevel mixed-effects logistic regression model was used to explore the association of the outcome variable with the explanatory variable, adjusted for potential confounders. We found that the prevalence of skilled delivery healthcare services uptake was 52.8%. Maternal women lacking empowerment were 21% less likely to uptake skilled delivery healthcare services (aOR=0.79, 95% CI, 0.64-0.97) compared to those highly empowered. This association remained consistent across all three domains, with maternal women lacking empowerment reporting lower likelihoods of skilled delivery healthcare services uptake. The findings of this research affirm the positive impact of women's empowerment on skilled delivery healthcare services uptake. Recommendations include increasing women's empowerment and raising awareness and education about the importance of skilled delivery healthcare services.
Measuring technological innovation and trade vulnerability within the critical supply chains: a framework for analysis
Authors: Eriksonas Linas
Published: January 2024

This article investigates the link between critical supply chains and technological innovation using Comtrade trade data (2020-2022) and patent data (from 2013). Focusing on critical materials and products as defined by the US Department of Trade, it examines how trade flows can effect patenting activities. The study explores the impact of export and import shares on innovation, measured by patent claims and assignees. Findings reveal that higher export shares boost innovation, while import shares correlate with diverse innovative activities. The article highlights the intertwined nature of trade and innovation in critical supply chains, underscoring its significance for economic and policy analysis.
Discrepancy Results of Treponemal Tests: Exploring the Associated Risk Factors Using Machine Learning Technology Based on 18 Years of Electronic Medical Records and National Claims Data
Authors: Wang Hsin-Yao , Hu Ru-Fang , Lin Ting-Wei , Lin Wan-Ying , Wang Yu-Chiang , Lu Jang-Jih , Tseng Yi-Ju
Published: January 2024

Background
Syphilis is becoming more prevalent and is diagnosed primarily through serologic tests. Confirmatory treponemal tests (TTs), such as Treponema pallidum particle agglutination (TPPA) and fluorescent treponema antibody absorption (FTA-Abs), are typically used. Although only one TT is needed for syphilis diagnosis, multiple TTs are still common in the disease course. Discrepant TT results can cause confusion and delay treatment. We aimed to explore the clinical characteristics of patients with discrepant TT results and develop a machine learning based tool to evaluate the risk of TT discrepancies.
Methods
In the retrospective cohort study, we linked electronic health records from a medical centerand national claims records in Taiwan between January 2001 and September 2018. Medical histories and demographic characteristics were considered as variables of interest to identify risk factors and develop machine learning models to assess the risk of TT discrepancy. We also analyzed the association between syphilis treatments and discrepant TT results.
Results
Among 5,780 eligible patients tested for syphilis, 133 (2.30%) had discrepant TT results. Risk factors associated with discrepant TT results were HIV and AIDS (adjusted odds ratio [aOR] = 2.6, 95% CI 1.4-4.7), osteoarthritis (aOR = 3.3, 95% CI 1.3-7.1), and pregnancy (aOR = 5.0, 95% CI 1.8-11.6). Patients with a top 5% risk probability from the LighGBM model were 10 times more likely to have discrepant TT results. For cases with discrepant TT results, TPPA was more likely than FTA-Abs to turn negative after treatment (OR 9.18, 95% CI 2.05-41.07).
Conclusions
Identifying risk factors and developing a machine learning based decision support tool could significantly aid in interpreting serologic tests for syphilis and guide accurate diagnosis.
Methodische Ansätze zu Evidenzsynthesen in der Bildungstechnologie
Authors: Buntins Katja , Bedenlier Svenja , Marín Victoria , Händel Marion , Bond Melissa
Published: January 2024

Methoden der Evidenzsynthese werden in den Sozialwissenschaften immer beliebter, auch im Bereich der Bildungstechnologie, wo die Menge der durchgeführten Sekundärforschung exponentiell zugenommen hat. Während Übersichten einen wertvollen Einblick in den Stand des Feldes geben können, wurden Fragen zur methodischen Strenge und Transparenz aufgeworfen. In dieser tertiären Übersichtsarbeit wird daher untersucht, wie transparent und reproduzierbar die Berichterstattung über die Methoden der Evidenzsynthese im Bereich der Bildungstechnologie in den verschiedenen Arten von Übersichtsarbeiten ist. Zu diesem Zweck wurde eine kritische Analyse einer Stichprobe von 446 Evidenzsynthesen in drei Sprachen (Englisch, Deutsch und Spanisch) durchgeführt. Systematic Review, Meta-Analyse und Literaturreview als die am häufigsten verwendeten Review-Typen wurden für die weitere Analyse. In der Stichprobe wurden Indikatoren für die Replizierbarkeit in kritischen Phasen der Überprüfung identifiziert und nach Überprüfungstyp (Forschungsfrage, Suchstrategie, Datenextraktion und Synthese) analysiert. Die Ergebnisse zeigen, dass die methodische Transparenz bei der Datenextraktion und -synthese erheblich verbessert werden kann, wobei bestimmte Arten von Übersichten bei den Indikatoren schlechter abschneiden als andere. Es werden Empfehlungen zur Verbesserung der methodischen Transparenz und Strenge der Evidenzsynthese im Bereich der Bildungstechnologie gegeben.
Karl Dedecius, 1921–2016
Authors: Chojnowski Przemysław
Published: January 2024

Karl Dedecius gilt als einer der produktivsten deutschen Übersetzer polnischer Literatur und als herausragende Persönlichkeit des deutsch-polnischen Dialogs in der zweiten Hälfte des 20. Jahrhunderts. Er starb am 26. Februar 2016 hochbetagt in Frankfurt am Main und hinterließ ein umfangreiches Œuvre, das ca. 200 übersetzte Bücher polnischer und russischer Literatur (darunter zahlreiche Anthologien) sowie mehrere essayistische Werke umfasst. Das Kernstück bilden die 50 Titel der von ihm initiierten und herausgegebenen "Polnischen Bibliothek" (1982–2000) sowie die sieben jeweils ca. 900 Seiten starken Bände des "Panoramas der polnischen Literatur des 20. Jahrhunderts" (1996–2000). Die Liste der von ihm übersetzten Autoren umfasst gut 300 Namen.
Horst Engert : Bibliographie
Authors: Žvaliauskienė Sidona
Published: January 2024

Die Bibliographie verzeichnet alle bisher ermittelten von Horst Engert verfassten bzw. übersetzten Texte.
Radiometric measurements at uranium mined-out sitesbefore their reclamation
Authors:   Navoi State Mining and Technological University, Nazarov Zhamoliddin , Allaberganova Gulchekhra ,   Navoi State Mining and Technological University, Pulatov Khairullo ,   Tashkent Institute of Chemical Technology, Muzafarov Amrullo ,   Navoi State Mining and Technological University
Published: January 2024

The article presents the results of radiometric measurements of various indicators for objects at uranium mined-out sites before their reclamation: specific activity of natural radionuclides, total effective activity, specific alpha activity, pH value of water extract, exposure dose rate of gamma radiation, equivalent equilibrium volumetric activity of radon, content of long-lived radioactive aerosols in the air, and density of radon molasses. The results were compared with the regulatory requirements established for both the population and personnel. The article shows that the radiation indicators at a man-made object differ from the background values for natural objects, i.e., uranium mining is a source of radioactive pollution of the environmen.
Study of the characteristics of a distributed gain amplifier based on GaAs field-effect transistors
Authors:   Tomsk State University of Control Systems and Radioelectronics, Gogolev Nikita I. , Salikh Ayatulla ,   Tomsk State University of Control Systems and Radioelectronics, Bragin Dmitry S. ,   Tomsk State University of Control Systems and Radioelectronics, Dmitriev Vladimir D. ,   Tomsk State University of Control Systems and Radioelectronics
Published: January 2024

The distributed amplifier is an effective solution for creating broadband amplifiers in wireless communication, pulse and measurement technology. In this study, a distributed amplification amplifier based on GaAs field-effect transistors was developed. The optimal number of amplification cells was determined and a cascaded distributed amplification amplifier with a schematic diagram operating in the range of 2 to 20 GHz was designed. Preliminary calculations of the main characteristics of the amplifier were also performed, and based on them, a model of the distributed amplification amplifier was constructed, which was simulated in CAD. The changes in the gain and output power when compressed by 1 dB depending on the number of amplification cells were analyzed. The results of the study can be used in designing distributed amplification amplifiers for various systems in modern radio electronics.
Results of the demand management project to ensure system reliability from the point of view of electricity consumers
Authors: Izmailov Yu. A. , Kosharnaya Yu. V.
Published: January 2024

In the Russian Federation an electricity demand management market is being formed, it is one of the tools that allows industrial consumers of electricity to receive financial rewards from the infrastructure of the electricity and capacity market. The paper considers the mechanism for managing the load of enterprises to ensure the system reliability of the unified energy system of Russia. The technical and economic possibilities of mechanisms for price-dependent reduction of consumption in the wholesale electricity market and load management (demand response) in the retail electricity market for consumers have been studied. The relationship between enterprise load management and the reduction in the price of electricity on the day-ahead market has been analyzed. The economic effect for electricity consumers from the introduction of a demand management mechanism in the electricity market has been determined. The directions of development of the load management mechanism to ensure system reliability in the unified power system of Russia have been described.
Chanoyu and Women’s Cultivation in Edo Woodblock Prints
Authors:   Association for International Tea Culture, Kim Jung-hui
Published: January 2024

This study examines images of women’s tea practice (chanoyu) found in Edo-period woodblock prints such as ukiyo-e and educational books, with a focus on its social and cultural meaning. As a social gathering men’s tea practice is often represented with an emphasis on the scene in which guests come together, drink tea, and socialize. Scenes of women’s tea practice in ukiyo-e prints, on the other hand, mostly depict the image of a woman who is making tea (temae) by herself and highlight her tea utensils. This paper maintains that such variation originates from different social expectation towards tea practices of men and women. It was educational books for women (jokunsho), in particular, that influenced the formation of the discourses on women and their tea practice in the Edo period. Jokunsho presented that by learning temae procedures for chanoyu women were able to acquire manner and etiquette, which were necessary in cultivating genteel femininity. This essay argues that women’s temae scenes depicted in ukiyo-e reflect the social awareness of women’s tea practice, which was encouraged by educational books.
The impact of entrepreneurial behavior on entrepreneurial human resources management: The mediating role of entrepreneurial orientation
Authors: Altahat Shadi , Alnadi Mohammad
Published: January 2024

Entrepreneurial human resources management can establish competitive advantages by consistently fostering superior human resources contributions within companies. This is achieved through the development of skilled employees who are passionate about delivering quality products and services. This study sets out to explore the role of entrepreneurial orientation for small and medium-sized enterprises (SMEs), particularly the relationship between entrepreneurial behavior and entrepreneurial human resource management. An online questionnaire technique was used to meet the research objectives. The study sample consisted of 356 participants from human resource management departments from 30 SMEs in the Al-Hassan Industrial Estate (HIE) in northern Jordan. The structural equation modeling (SEM) was used to examine the data. The results displayed that entrepreneurial behavior positively and significantly impacts both entrepreneurial human resources management and entrepreneurial orientation. Additionally, entrepreneurial orientation positively impacts entrepreneurial human resources management. Entrepreneurial orientation partially mediates the relationship between entrepreneurial behavior and entrepreneurial human resources management. According to these findings, human resources management policies and practices influence the level of entrepreneurship within an organization.
“OLAN” VE “OLMASI GEREKEN” ARASINDA DEMOKRASİ: ALİ YAŞAR SARIBAY’IN DÜŞÜNCESİNDE DEMOKRASİNİN SOSYOLOJİK VE FELSEFİ ARKA PLANLARI
Authors: GAYIRHAN Günhan , ERAYMAN İbrahim Oğulcan
Published: January 2024

Demokrasi ile ilgili en tartışmalı sahalardan birini, mevcut demokrasi ile ideal demokrasi arasındaki ilişkinin oluşturduğunu ifade edebiliriz. Bu makale, bahsi geçen bu ilişkiyi Ali Yaşar Sarıbay’ın demokrasi kavramsallaştırması bağlamında incelemeye gayret etmektedir. Ayrıca bu çalışma, Sarıbay’ın demokrasi için sunduğu çerçevenin felsefi ve sosyolojik arka planını da açımlamayı amaçlamaktadır. Bu arka plan, en temelde, birbirleriyle ilişkili iki temel prensibe, bireylerin kendi çıkarlarına sınır koyabilmelerine ve “ötekine” karşı sorumluluk hissi duymaya dayanmaktadır. Bu bağlamda, Sarıbay’ın demokrasi vizyonunun (olan -güncel- ve olması gereken -ideal- arasında) günümüz toplumları bakımından hayati önem kazanan “beraber” yaşama pratiklerine duyulan ihtiyacın giderilmesine önemli bir katkı sağlayabileceğini iddia ediyoruz.
Gender-based Dayah: The Role of Female Ulama in Trauma Recovery Strategies for Sexual Violence Victims in Aceh
Authors: Husna Fathayatul , Fitri Ainal
Published: January 2024

This article delves into the escalating cases of sexual violence in Aceh and the imperative need for trauma recovery efforts. Umi Hanisah, an Acehnese female ulama and founder of Dayah Diniyah Darussalam, the sole gender justice-oriented Islamic boarding school in Aceh, is pivotal in addressing this issue. Employing a descriptive qualitative approach, this research explores Umi Hanisah’s endeavors to heal the trauma of child victims of sexual violence. Data collection includes in-depth interviews, observation of the Dayah environment, documentation, and literature studies. Findings reveal Umi Hanisah’s authoritative approach in accommodating and recovering victims through a religious lens. She contends that the Islamic religious approach can emancipate victims from the chains of trauma, supplemented by Aceh’s local wisdom values as a foundation for trauma recovery, empowering victims to reintegrate into their communities.
Improving the Self-concept of Women Commercial Sex Workers with Group Counseling Solution-focused Brief Counseling (SFBC) Approach
Authors: Netrawati Netrawati , Syukur Yarmis , Setiawan Arif
Published: January 2024

This study underscores the critical need for mental health intervention among commercial sex workers undergoing rehabilitation, focusing on gender issues, particularly women choosing alternative paths in this field. The psychological challenges linked to their identity as female sex workers require the identification and enhancement of their self-concept. The research evaluates the effectiveness of the Solution-focused Brief Counseling (SFBC) approach in fortifying the self-concept of women involved in commercial sex work through group counseling services. Conducted at the Andam Dewi rehabilitation center in Solok with 21 female participants, the study adopts a quasi-experimental design. Results affirm the efficacy of SFBC, highlighting its potential to improve women’s self-concept in this specific context. This study contributes to an underexplored domain, urging counselors at rehabilitation centers to embrace group counseling services and SFBC to enhance the self-concept of women engaged in commercial sex work.
Rubber Farmers Children’s Perceptions of Continuing Business between Generations: Case Study in Banyuasin Regency, South Sumatra
Authors: Adriani Dessy , Septiani Donna
Published: January 2024

The declining interest of young people in farming extends beyond the food sector to include the plantation sector, warranting attention. This study addresses the insufficient exploration of the aspirations of plantation sector farmers’ children to pursue farming. The research focuses on analyzing the perceptions of farmers and their offspring regarding continuing rubber farming and identifying influencing factors in Ujung Tanjung Village, Banyuasin III District, Banyuasin Regency, South Sumatra. Employing a random sampling survey method, 36 school-age children were interviewed from a population of 175. Findings indicate that the children’s interest in rubber farming is relatively low (average score: 53.25), influenced by factors such as land area, participation in family farming, and agricultural extension. Although a generational transition in agricultural activities is observed in the village, guidance and counseling remain crucial to address farmer children’s perceptions.
Prevention of Divorce through the Marriage Certification Program in Cilacap Regency, Central Java: The Lens of al-Ghazālī’s Maṣlaḥah
Authors: Santoso Selamet , Arifin Tajul , 'Ain I. Nurol , Nurrohman Nurrohman
Published: January 2024

Cilacap Regency, Central Java, has experienced a significant increase in divorce cases and is ranked the highest in the region. In response to this trend, the Ministry of Religious Affairs in Cilacap launched a marriage certification program to counteract the spike in divorce rates. Using a qualitative research design, this study used primary data from interviews and secondary data from an information review involving KUA officers and certification counselors in Cilacap Regency. Data validation used the triangulation method, and analysis interpreted the information thematically through al-Ghazālī maṣlaḥah theory. This study aims to examine the application of al-Ghazālī maṣlaḥah theory in the implementation of the marriage certification program in Cilacap Regency. The findings of this study highlight the program’s alignment with al-Ghazālī maṣlaḥah theory, categorizing it as maṣlaḥah ḍarūriyyah (primary), which requires an immediate implementation to uphold the objectives of Sharia: safeguarding religion, mind, soul, property, and offspring.
Algorithm for Optimizing the Initial Conditions for a Chemical Reaction Based on a Kinetic Model
Authors:   Ufa University of Science and Technology, Antipina Evgenia Viktorovna , Mustafina Svetlana Anatolievna ,   Ufa University of Science and Technology, Antipin Andrey Fedorovich ,   Ufa University of Science and Technology
Published: January 2024

A numerical algorithm has been developed to search for the optimal values of the concentrations of chemical reaction reagents. The statement of the problem of determining the optimal initial concentrations of the initial substances on the basis of the kinetic model of the reaction, which is a system of ordinary differential equations, is formulated. To solve the problem, a genetic algorithm with real coding is given. The algorithm is modified taking into account the restriction on the values of the initial concentrations and the condition imposed on the total initial concentration of the reagents. A computational experiment was carried out for the reaction of the synthesis of benzyl butyl ether under the action of copper-containing catalysts. The initial concentrations of the initial substances are determined at which the highest values of the concentrations of the target reaction products are achieved.
Modeling and Stabilization of an Irregular Pricing Mechanism on a Network of Local Markets
Authors:   HSE University, Alexeeva Tatyana Anatolyevna ,   Saint Petersburg School of Physics, Mathematics, and Computer Science, Kuznetsov Nikolay Vladimirovich ,   St. Petersburg State University,   Institute for Problems in Mechanical Engineering of the Russian Academy of Sciences (IPMash RAS), Mokaev Timur Nazirovich ,   St. Petersburg State University, Posudin Konstantin Mikhailovich ,   St. Petersburg State University
Published: January 2024

The accuracy of forecasting the expected values of economic indicators under conditions of irregular dynamics has a key role in taking optimal management decision-making. The solution of this current and complex task requires the use of modern artificial intelligence technologies, the wide introduction of which into the economy is aimed at by the Federal project ``Artificial Intelligence''. We demonstrate the effectiveness of combining artificial intelligence technologies and classical methods of mathematical control to detect irregular dynamics in the pricing mechanism and stabilize the revealed irregular mode through a small control action using a pricing model in the market of short-term goods as an example.
Applying a Power Transformation to the Orbit of the 2nd Painleve Equation and Solving Differential Equations with Polynomial Right-hand Sides Via the 2nd Painleve Transcendent and in Polynomials
Authors:   Mozhaisky Military Space Academy, Khakimova Zilya Nailevna , Timofeeva Larisa Nikolaevna ,   Mozhaisky Military Space Academy, Atojan Ajkanush Ashotovna ,   Mozhaisky Military Space Academy
Published: January 2024

The 2nd Painleve equation is considered as a representative of the second-order class of ordinary differential equations (ODEs) with polynomial right-hand sides, as well as of the more general second-order class of equations with fractional polynomial right-hand sides. The second PainlevГ© equation with three terms on the right side has an orbit in the class of fractional polynomial equations with respect to the pseudogroup of the 36th order, and in the absence of the 3rd term вЂ“ the 60th order. This paper presents a power transformation with an arbitrary parameter that preserves the polynomial or fractional polynomial form of the equations. This power-law transformation is applied to the orbital equations of the 2nd PainlevГ© equation with three and two terms on the right-hand sides of the equations. Pseudogroups of transformations induced by the above-mentioned pseudogroups of the 36th and 60th orders are constructed. All equations with one-constant arbitrariness corresponding to the vertices of the graphs of induced pseudogroups are found. General solutions of all found equations are obtained through the 2nd PainlevГ© transcendental or in polynomials. A theorem is presented that allows, using the scaling operation, to find general solutions to all the above equations with arbitrary coefficients.
THE PHILOSOPHER AND HIS PHILOSOPHIES. ORTEGA, HUSSERLIAN PHENOMENOLOGY AND BEYOND
Authors:   National University of Distance Education (UNED-Madrid), DÍAZ ÁLVAREZ JESÚS M. , BRIOSO JORGE ,   Carleton College
Published: January 2024

This article tries to unravel some of the main clues provided by Ortega on his understanding of philosophy. The thesis we defend is that the Spanish philosopher maintains two slightly different answers concerning the question what is philosophy, though Ortega does not acknowledge them in the explicit narrative of his thinking. This, we believe, creates tensions in his late second philosophical model, as he does not fully break away from certain “adherence” or “mannerisms” associated to his early model. In this respect, Ortega would be a thinker who lives between two philosophical worlds, someone who sees, narrates and interprets the philosophical shock wave occurring at his time, but does not quite let go of the old intellectual constructions. To support our thesis, we will compare two texts, his 1929 lectures What is Philosophy?, and his Notes on Thinking, from 1941. In the period between these two works, Ortega seems to move from a more “traditional,” “universalistic,” “transcendental,” in short, Husserlian phenomenological understanding of philosophy, to a more historicist, hermeneutical, and pragmatic one, which lays the emphasis on the plurality of discourses on the sense, the contingency of the philosophical narrative itself, and even the very possibility of its ending, at least in its more “metaphysical” and classical form.
THE EMERGENCE OF REALITY: ZUBIRI BEFORE MEETING HEIDEGGER
Authors:   Xavier Zubiri Foundation, GONZÁLEZ ANTONIO
Published: January 2024

It is common to assume of an “objectivist” stage of Zubiri, prior to his meeting with Heidegger in Freiburg. However, if we analyze Zubiri’s philosophy before his stay in Freiburg, we already find a “metaphysical” orientation, and not merely an objectivist one. This orientation is intrinsically related to the early appearance of the notion of “reality” in his courses. The appearance of his concept of reality is at least partially motivated by Zubiri’s early reading of Heidegger’s habilitation thesis on Duns Scotus. Zubiri discovered in Heidegger the possibility of trying to carry out a phenomenological characterization of reality, which took him beyond the conception, basically idealistic, of being as a “position” or as a “belief.” With Heidegger, Zubiri was able to sustain that reality is not something extra animam. However, Zubiri could not follow Heidegger in his conceptualization of reality based on human existence, and with this he began his own path in philosophy. A path that, in a certain sense, breaks with all phenomenology, because reality is located at a moment prior to the meaning of things for a subject or for a human existent. And yet, a path that continues the phenomenological claim of a descriptive fidelity to the things themselves.
THE TRANSCENDENTAL AND THE MUNDANE SPHERES: ARE THEY REALLY ONTOLOGICALLY DISCTINCT?
Authors:   University of Patras, LIVADAS STATHIS
Published: January 2024

As implied by the title this article deals with a key question running through the history of philosophy virtually since antiquity. This is the question of the relationship, on ontological grounds, of the transcendental and the mundane “universes” to the extent that the nature of transcendence, even as detached from the metaphysical sphere and recalibrated in terms of immanence in the broadly conceived subjectivist tradition, it is still a highly controversial issue primarily in continental philosophy. This is especially true in view of the obvious incompatibility, at least in a naive sense, of the transcendental and the mundane contexts for which the philosophical discussion on phenomenological grounds is still open. My own arguments on the issue are mainly based on the Husserlian and Heideggerian narratives and also on E. Fink’s approach to the transcendence versus mundanity ontological problematic. On these prompts I set out to defend the position that there are serious reasons to regard the realm of transcendence as ineluctably constrained by mundanity concerns. More concretely I will try to show that there is no way, at least in the context of the phenomenological discourse, to do away with a kind of mundanity influence even in the most pure transcendental level involving the cornerstone of Husserlian transcendental phenomenology which is the concept of absolute ego. My overall approach, more than an attempt at vindicating Fink’s objections as to the purely transcendental level reached after the radical phenomenological reduction, is a demonstration of the conceptual pitfalls or even circularities involved along the way in trying to establish a sound foundation for a purely transcendental ontological level.
AUDITORY IMAGE: PHENOMENOLOGICAL LOCALIZATION OF THE PROBLEM
Authors:   Reshetnev Siberian State University of Science and Technology, MEDOVA ANASTASIA ,   Krasnoyarsk State Pedagogical University named after V. P. Astafyev
Published: January 2024

The article aims to concretize the phenomenological account concerning the problem of an auditory image. The author considers auditory imagery as a scientific object and compares different treatments of the problem to fix the potential and advantages of its phenomenological interpretation. In the first stage of the study, the author distinguishes the key characteristics of the image by means the lexical analysis. This is the perceptual (predominantly visual) nature of an image, integrality, and essentiality (image as an idea). In the second stage, the understandings of the mental and auditory imagery in physiology, experimental psychology, music psychology, musicology, and interdisciplinary studies are described. In the third stage, the peculiar phenomenological ways of the comprehension of an auditory image are revealed. The phenomenological interest is to pick out consciousness which perceiving of an image equally from the process of perceiving and from entailing in an image. The specific phenomenological stance is placing an auditory image on the bound of transcendent (the process of perceiving) and immanent (an image that is already perceived). The auditory image is conceived as the unity of Modi of its givenness. Most fecks of this Modi are original, they cannot be transferred into other science scopes: they are the interconnection of all moments of the temporal unfolding, self-organization in the time, self-referentiality, non-semanticity, periodicity/randomness, eventuality, quasi-embodiment (physicality). Solely phenomenological problems are problems of the constitution of an auditory image, its life-horizon, intersubjectivity, and regional matching. The author infers that phenomenology does not conceive auditory image as sustained auditory representation, associated with acoustic memory. Its perceptual nature does not play a key role here. Moreover, the perceptual-semantic duality of the image is not fixed by the phenomenological description. The phenomenological approach is unique because it researches auditory data exhaustively but does not use semantic and referential analysis of them. The main feature of phenomenological description is the focus on the unity of auditory image: All the elements of auditory data are interpreted in their synthesis as the different levels of the unity of hearing image. Thus, the phenomenological approach as a whole is the most promising for comprehending such a dominant quality of the auditory image as integrality.