bluuebunny/crossref_metadata_2025 huggingface dataset:
An analysis of study trends on Korean tense
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Ma Xiaolin
Published: July 2022

Objectives The purpose of this study was to analyze the trends of the studies on tense in the education field of Korean language and to examine the results of the studies. On the basis of these analyses, future research subjects were presented. Methods The number of papers of the subject of analysis is totally 172 papers, including 111 graduate theses and 61 articles of academic journal. The research trends were analyzed by means of research times, research themes, research methods, and research contents and then according to lower standard of analysis, these papers were classified. By making the use of analysis methods such as summary of content, frequency analysis, and data statistics, the trends of studies were analyized. Results As a result, for over 30 years the researches on tense have been steadily ongoing in the education field in Korean language and quantitative growth of this field has been achieved. Studies on the educational plan of tense expressions and on tense expression acquisition have been main subjects in this period. Research methods have been unequally biased in literature research and survey research ones. The most studies are especially related to the past tense in Korean language and tense expressions realizing at the end of sentences. Conclusions By analyzing these research trends, several tasks of future research were proposed. First, themes of tense research need to be diversified. In addition, studies observing the present tense and the future tense are necessary and studies on complex sentence tense are also urgently required.
Auto-Ethnography on a Student Athlete-Turned Vocational Counselor’s Career Transition Experience
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi JungWon
Published: July 2022

Objectives The purposes of this study is to investigate my career transition experience in life development from a student athlete to a vocational counselor and the meaning of my experiences. The study also aimed to have a self-examination and understand clients in a career transition. For these purposes, the researcher set the following research questions based on a self-examination into my experiences as the research participant: first, what were my various career transition experiences from a student athlete to a vocational counselor?: second, what meaning do various career transitions have from a student athlete to a vocational counselor? Methods The purposes of this study was analyzed and used as self-reflection data through self-cultural descriptive papers that mainly used self-reflection data related to career transition. In order to secure the reliability and validity of this study, the confessional-sentimental writing method and analytical-interpretative writing method among the writing techniques suggested by Chang(2008) were mainly used to collect research data. It was reviewed by two experienced counseling professors who has extensive experience in qualitative research methods. Results The findings were as follows: First, a career transition is not a matter of change, but a matter of how one perceives his or her change. A counselor should understand his or her clients as individuals with their own relationships and career transitions and provide them with help. Secondly, I saw an occupation as a series of completing myself and exhibited a self-examination attitude for adjustment with a set of proper coping strategies including a positive and optimistic attitude toward a career transition and an inquiry into my perceptions of a career transition for adjustment and my personal resources. Conclusions These findings will offer some counseling tools to help individuals make constant attempts at a career transition and explore and accept their meaning in their career transition process, including the meaning and concept of career, vocational changes according to their individual internal and external environments, family relationships, starting, adjusting to, and quitting a career transition, and reemployment, efforts.
Content System and Teaching/Learning Case Study for Systematic Convergence of Artificial Intelligence and Science Subjects
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Ju-Young , Kim Kwihoon , Kang Seong-Joo
Published: July 2022

Objectives The purpose of this study is to propose a content system for systematic linkage, integration, and convergence of artificial intelligenc and science subjects and teaching/learning cases based on the content system. Methods First, a draft of the content system was devised by analyzing and extracting content elements for each area of artificial intelligence and science subjects for AI-SCIENCE convergence education through literature research. Second, the validity of the AI-SCIENCE convergence education content system was verified through expert Delphi. Third, based on the derived content system, teaching/learning cases for AI-SCIENCE convergence education were proposed. Fourth, the validity of the teaching and learning case for AI-SCIENCE convergence education was verified through expert Delphi. Fifth, the implications of the Delphi test results were derived and the AI-SCIENCE convergence education content system-based teaching/learning case was systematized. Results First, as the knowledge of AI-SCIENCE convergence education, learning hierarchies were established by grades 3-4, 5-6, and middle school student development stages and content levels. 2 areas and 4 core concepts of artificial intelligence education, 15 areas and 35 core concepts of science education were selected. Second, based on the analyzed and extracted content system, teaching and learning cases were presented under the theme of ‘planet’. Third, to verify the validity of the content system and teaching/learning cases, expert Delphi was conducted and opinions were collected. As a result, the field composition of AI-SCIENCE convergence education met the conditions of content validity in terms of suitability and importance. Conclusions By analyzing and extracting the content system related to the knowledge and understanding of AI-SCIENCE convergence education, it is possible to facilitate the connection, integration, and convergence of the learning content in the AI field with science in terms of subject characteristics. In addition, subjects other than science subjects will also be able to utilize the presented content system in connection with the content system of each subject.
A case study on the exploration of the mathematical internal connections of quadratic curves: focusing on students at S gifted school
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Kyeongsik , Kang Hyun Young
Published: July 2022

Objectives In this study, we developed instructional materials that allow students to explore the mathematical internal connections of quadratic curves using a technology tool, and analyzed the results of students to understand how students perceived the mathematical internal connections of quadratic curves. Also, we tried to find out what the hindrance factors were for perceiving the mathematical internal connections. Methods For this purpose, we developed instructional materials for 16 first-year students attending S gifted school located in a small city to explore the mathematical internal connections using GeoGebra. Moreover, the developed instructional materials were applied to the students, and the students' results were analyzed in terms of the mathematical internal connections between algebraic representations and geometric representations and between different mathematical objects. Results As a result of analyzing the results of the students, the students were able to understand the quadratic curves well in the process of connecting geometric expressions based on the definition of the quadratic curves, and had a motivation to find other tasks on their own. In the process of connecting different quadratic curves, the students constructed algebraic expressions from definitions and understood the connections of different quadratic curves in the process of finding common math expressions between each expression. In addition, students came to understand the connections of quadratic curves through the process of plotting graphs by inputting common expressions into GeoGebra. However, in some cases, students' prior learning acted as a hindrance to their exploration of mathematical intenal connections. Conclusions Using the materials developed in this study, students were able to explore the mathematical internal connections of quadratic curves with a technology tool. In addition, the mathematical knowledge learned in advance before lessons could act as a hindrance factor in exploring the mathematical internal connections.
Архитектура как феномен эволюции универсума. Часть 2
Authors: Ткачёв Валентин
Published: July 2022

Установление универсальных закономерностей процессов морфогенеза материи во вселенском и земном масштабах обнов­ляет устоявшиеся представления об архитектуре как ортодок­сальном средстве материальной и духовной организации бытия.

Стремительность цивилизационных преобразований на планете заставляет переоценить вклад человека в развитие архитектуры и адаптировать стратегию его отношений к не­зависимым формам преобразования среды.

Особенность архитектуры - её структурные построения, корректируются усилиями человека, представляющего хотя и разумный, но все-же только инструмент Универсума, нередко нарушающий линейные процессы эволюции. Виной всему - антропный принцип, наследовавший древний антропомор­физм и средневековый гилозоизм, утверждавшие человека как венец мироздания, довлевшие на самосознание человека сотни лет и тормозившие развитие цивилизации.

Эта часть статьи посвящена современной интерпретации этого принципа и тех его последствий в теории и практике деятельности человека, которые во многом содейссоответ- ствуют до сих пор алогичным, с точки зрения автора, пред­ставлениям о мире, хотя и это всего лишь гипотеза, предла­гаемая критически настроенным дилетантом.

Продолжение.

Начало см. «Academia. Архитектура и строительство», № 1, 2022 год, с. 12-18.
Prevalência de distúrbios osteomusculares em trabalhadores durante a pandemia de COVID-19 no Brasil
Authors: Santos José Wendel dos , Moura Henrique Martim de , Martins João Gabriel Santos , Santos Pedro Vieira Souza , Monteiro Luciano Fernandes
Published: July 2022

Os distúrbios osteomusculares relacionados ao trabalho (DORT) representam um importante problema de saúde pública em todo o mundo. Dada a situação especial ocasionada pela pandemia do novo coronavírus, surgiu a necessidade de conhecer quais as repercussões do modelo de trabalho adotado na saúde dos trabalhadores. Nesta perspectiva, este estudo teve como objetivo estimar a prevalência de DORT em trabalhadores durante a pandemia de COVID-19 no Brasil. Para tanto, um estudo exploratório-descritivo foi conduzido com 4.891 trabalhadores. As informações foram coletadas via internet, por meio de formulário estruturado. A sintomatologia dolorosa autorreferida pelos trabalhadores foi avaliada pelo Nordic Musculoskeletal Questionnaire (NMQ) e Visual Numeric Scale (VNS). Os resultados indicaram uma prevalência de DORT em 64% dos participantes, sendo a coluna lombar (79,5%), punhos/mãos (68,6%), pescoço (64,8%) e coluna dorsal (57,8%) as regiões anatômicas mais afetadas durante o teletrabalho. A intensidade da dor variou entre leve e forte, sobretudo entre as mulheres (p < 0,05). A sintomatologia dolorosa reportada neste estudo revelou-se com potencial de cronificação, o que pode resultar na incapacidade funcional permanente do trabalhador. Nesse sentido, as medidas de controle determinadas pelas autoridades competentes devem ser viabilizadas pelos empregadores para promover a saúde desses profissionais enquanto durar o trabalho remoto.
Remoción de material de obturación de molares utilizando punta ultrasónica Clearsonic y limas Fanta
Authors: I B Britos , S Salduna , G Martin , M P Landa
Published: July 2022

INTRODUCCIÓN: El retratamiento endodóntico es un procedimiento no quirúrgico que involucra laremoción de material de relleno del conducto radicular. La hipótesis del presente estudio establece que eluso del instrumental Fanta R3 (25.06) y de la punta Clearsonic R1 remueven el material de relleno delconducto mesio-vestibular de molares inferiores.OBJETIVO: Evaluar la eficacia de la punta ultrasónica Clear Sonic y lima Fanta en la desobturación deconductos radiculares previamente obturados con 2 selladores diferentes. Objetivos específicos: 1)Comparar la remoción del material de obturación de conductos mesio-vestibulares de molares inferiorespreviamente obturados con AH Plus y Bio C Sealer. 2) Evaluar el remanente del material de obturación enlos 3 tercios del conducto radicular, posterior al uso de la punta Clear Sonic y la lima FANTA.MATERIAL Y MÉTODO: Se seleccionaron 20 conductos mesio-vestibulares de molares inferiorespreviamente obturados con 2 selladores diferentes, los cuales se dividieron en 2 grupos experimentales de10 piezas dentarias cada uno (n=10). Se tomaron radiografías digitales de las muestras en sentido proximaly ortorradial. Para la desobturación, se utilizó una punta ultrasónica con diseño en forma de flecha R1 ClearSonic montada en un equipo de ultrasonido P4 Ultrasonic Scaler (BAOLAI), el instrumento se activódurante 3 ciclos de 20 segundos realizando un movimiento de picoteo hacia adentro y afuera con el objetivode retirar el material de relleno. Entre cada ciclo el instrumento fue retirado y limpiado. La lima FANTA(AF Blue R3) se utilizó en el tercio coronario, medio y apical. En este último tercio hasta la longitud detrabajo realizando movimientos de entrada y salida. Se tomaron radiografías digitales en sentido proximal.Las imágenes fueron evaluadas según un Score, establecido del 0 al 4. Los datos fueron recolectados enuna hoja de captura de datos y se realizó la prueba de Mann Whitney.RESULTADOS: La remoción del material de obturación no reveló diferencias significativas entre ambosselladores (AH Plus y Bio-C Sealer). Se observó que la cantidad y ubicación del material remanente, tantoen el tercio coronal, como en el medio y apical del conducto mesio- vestibular de molares inferiores, fuesimilar con ambos selladores.CONCLUSIONES: El uso de la punta Clear Sonic y las limas Fanta reciprocantes removieron el materialde obturación, sin embargo, no lo eliminaron por completo. La cantidad de material de obturaciónremanente en los tres tercios fue similar en ambos grupos, independientemente del sellador utilizado.
The ARC Procedure - an innovative non touch technique to obtain an endometrial biopsy at the time of vaginoscopy avoiding the use of a speculum.
Authors: Griffin Christopher , Cartmill Richard , Chaudhuri Amit
Published: July 2022

We have described how to perform blind endometrial sampling at the time
of outpatient vaginoscopy without the use of a speculum in a true no
touch technique.
Approximation by q-Bernstein-Stancu-Kantorovich operators with shifted knots of real parameters
Authors: Ayman Mursaleen Mohammad , Kilicman Adem , Nasiruzzaman Md.
Published: July 2022

Our main purpose of this article is to study the convergence and other related properties of q-Bernstein-Kantorovich operators including the shifted knots of real positive numbers. We design the shifted knots of Bernstein-Kantorovich operators generated by the basic q-calculus. More precisely, we study the convergence properties of our new operators in the space of continuous functions and Lebesgue space. We obtain the degree of convergence with the help of modulus of continuity and integral modulus of continuity. Furthermore, we establish the quantitative estimates of Voronovskaja-type.
Microstructure and mechanical properties of aluminium matrix boron carbide and carbon nanofiber reinforced hybrid composites
Authors: Okay Faik , Islak Serkan
Published: July 2022

In this study, aluminium matrix boron carbide (B4C) and carbon nanofiber
(CNF) reinforced hybrid composite was produced by powder metallurgy method
and their microstructure and mechanical properties were investigated. The
samples were produced at 6 percentage volume ratios using hot pressing
technique. Microstructure examination, hardness measurement, transverse
rupture test, and wear tests were carried out in order to determine the
mechanical properties of the samples. Also three-point bending test was
performed to determine their transverse rupture strength (TRS). Wear tests
were carried out based on the ball on disc method. The microstructure
examination revealed that the reinforcing elements were relatively
homogeneously distributed in the aluminium matrix. In addition, the fracture
was brittle due to the notch effect and agglomeration occurred with
increasing amount of CNF. As the CNF amount of the samples increased, their
hardness values increased but their TRS values decreased. Results of the
wear test indicate that the increased amount of CNF increased the wear
resistance. The friction coefficient values of the samples varied between
0.535 and 0.646. When the hardness was examined together with TRS and wear
test results, the most suitable sample was determined to be Al-7%B4C-1%CNF
Rate coefficients for h+ ions in n-Butanol gas
Authors: Nikitovic Zeljka , Raspopovic Zoran
Published: July 2022

In this work we show predictions for the low energy cross sections and transport properties for the H+ ions in n-Butanol gas. These data are needed for modelling in numerous applications of technologically importance. Appropriate gas phase enthalpies of formation for the products were used to calculate scattering cross section as a function of kinetic energy. Calculated cross sections can be used to obtain rate coefficients as a function of E/N (E -electric field strength; N-gas density) for H+ in n-Butanol gas.
Mechanical properties of biomass-derived silica nanoparticles reinforced PMMA composite material
Authors: Vuksanovic Marija , Mladenovic Ivana , Tomic Natasa , Petrovic Milos , Radojevic Vesna , Marinkovic Aleksandar , Jancic-Heinemann Radmila
Published: July 2022

Rice husk was used to produce silica particles, which were then used to
reinforce the polymer matrix. The synthesized SiO2 particles were
characterized using X-ray diffraction, Fourier transforms infrared
spectroscopy (FTIR) and scanning electron microscopy with EDS. In a PMMA
matrix, prepared SiO2 particles in amounts of 1, 3, and 5 wt.% were used as
reinforcing agents. The goal of this research was to see if SiO2 particles
had any effect on the mechanical properties of polymer composite materials.
The morphology of the composites was examined using a field emission
scanning electron microscope (FE-SEM). Vickers microindentation hardness and
impact testing were used to determine the mechanical properties of the
obtained composites. The indentation creep?s behavior of a
polymethylmetacrylate (PMMA) composite material with varying amounts of
nanoparticles (SiO2) was investigated and analyzed.
Development of women’s movement in India: A historical perspective
Authors: Bhat Rouf , Wani Mohd
Published: July 2022

The purpose of this paper is to look at the antecedents of the Indian women?s
movement and the achievements before and after independence. The status of
women has been a central concern of many reform movements in India. Prior to
India?s independence, the organizations and groups that addressed social
issues and sought change for women were closely associated with the
independence movement. The women?s movement during the 19th century in India
emanated from the broader social reforms movement. Consequently, the 20th
century freedom movement and women?s rights movement in the post-1970s has
brought to the fore a wide range of women?s concerns. The subsequent events
like the constitutional promise of gender equality, Towards Equality Report
prepared by the Committee on the Status of Women in 1974 have surely
promoted women?s concern to some extent. All these achievements were the
result of women?s movement groups that worked for the promotion of women?s
rights and equality. In the above-stated context, this paper also analysis
the issues of women?s justice and equality taken up by women?s groups in pre
and post-independent India.
A new fractional thermal model for the Cu/Low-k interconnects in nanometer integrated circuit
Authors: Zhang Pei-Ling , Wang Kang-Jia
Published: July 2022

In this paper, the Cu/Low-k interconnects in a nanoscale integrated circuit are considered. A new fractal conventional heat transfer equation is suggested using He?s fractal derivative. The two-scale transform method is applied for solving the equation approximately. The new findings, which the traditional differential models can never reveal, shed a bright light on the optimal design of a nanoscale integrated circuit.
Optimal design of passive solar building
Authors: Ma Jing , Liu Yin , Cui Xiangna , Wang Shun , Miao Huiping , Meng Zhaofeng
Published: July 2022

A passive solar building cannot only save cost and reduce energy consumption,
but also benefit the harmonious development of society. This paper
introduces an optimal design strategy by taking into account its external
environment, the building layout, the shape coefficient, the building
envelope, and the building structure. An example is given to reveal various
concepts and their applications.
Macromolecular-scale electrospinning controlling inner topologic structure through a blowing air
Authors: Tian Dan , He Ji-Huan
Published: July 2022

Macromolecules are the foundation stone to construct a nanofiber in the
electro-spinning. Their distribution and orientation greatly affect the
product?s properties. In this paper, a rotary blowing air is used to
control the radial topological structure of a nanofiber, and a
macromolecule-scale inner structure can be designed. The influence of the
flow properties on nanofibers? mechanical properties is studied
experimentally.
The Audit Quality Effects of Small Audit Firm Mergers in the United States
Authors: Christensen Brant , Smith Kecia Williams , Wang Dechun , Williams Devin
Published: July 2022

Increased audit regulation, coupled with reports of frequent mergers among smaller audit firms, creates a dynamic environment in which to assess changes in the U.S. audit market. We examine the audit quality consequences of audit firm mergers between small audit firms that audit public clients, a topic about which little is known. Using a sample of small audit firms each involved in a single merger during 2004–2016, we find consistent evidence that post-merger audit quality decreases when PCAOB-identified audit deficiencies and audit fees are used as proxies for audit quality. In addition, we find weak evidence of lower post-merger audit quality when examining discretionary accruals, and no conclusive post-merger audit quality effect for the probability of misstatements. Overall, our findings provide evidence regarding the audit quality consequences of some small audit firm mergers in the United States.

Data Availability: Data are available from the public sources cited in the text.

JEL Classifications: M42.
Sustained Proinflammatory Effects of Hypoglycemia in People With Type 2 Diabetes and in People Without Diabetes
Authors: Verhulst Clementine E.M. , van Heck Julia I.P. , Fabricius Therese W. , Stienstra Rinke , Teerenstra Steven , McCrimmon Rory J. , Tack Cees J. , Pedersen-Bjergaard Ulrik , de Galan Bastiaan E.
Published: July 2022

Iatrogenic hypoglycemia activates the immune system and is associated with an increased risk for atherosclerotic disease. We determined acute and long-term effects of insulin-induced hypoglycemia on inflammatory markers in humans with or without type 2 diabetes. A total of 15 adults with type 2 diabetes and 16 matched control subjects (17 men and 14 women, age 59.6 ± 7.1 years, BMI 28.5 ± 4.3 kg/m2) underwent a hyperinsulinemic-euglycemic (5.31 ± 0.32 mmol/L) hypoglycemic (2.80 ± 0.12 mmol/L) glucose clamp. Blood was drawn during euglycemia and hypoglycemia and 1, 3, and 7 days later to determine circulating immune cell composition, function, and inflammatory proteins. In response to hypoglycemia, absolute numbers of circulating lymphocytes and monocytes significantly increased and remained elevated for 1 week. The proportion of CD16+ monocytes increased, and the proportion of CD14+ monocytes decreased, which was sustained for 1 week in people without diabetes. During hypoglycemia, ex vivo stimulated monocytes released more tumor necrosis factor-α and interleukin 1β, and less interleukin 10, particularly in people with diabetes. hs-CRP and 25 circulating inflammatory proteins increased, remaining significantly elevated 1 week after hypoglycemia. While levels at euglycemia differed, responses to hypoglycemia were broadly similar in people with or without type 2 diabetes. We conclude that hypoglycemia induces a proinflammatory response at the cellular and protein level that is sustained for 1 week in people with type 2 diabetes and control subjects.
A mean 4-year evaluation of infection control rates of hip and knee prosthetic joint infection-related revision arthroplasty: an observational study
Authors: Van Dijk Bruce , Nurmohamed F Ruben H A , Hooning van Duijvenbode J Fred F , Veltman Ewout S , Rentenaar Rob J , Weinans Harrie , Vogely H Charles , Van der Wal Bart C H
Published: July 2022

Background and purpose: The long-term results of the 1- or 2-stage revision procedure and infection-free prosthesis survival in a tertiary referral center are unknown. In this retrospective observational study, the long-term results of infection control and infection-free prosthesis survival of the periprosthetic joint infection-related 1- and 2-stage revision procedure are evaluated. Furthermore, the merits of performing an antibiotic-free window in the 2-stage revision is evaluated.Patients and methods: All patients who received a 1- or 2-stage revision procedure of the hip or knee between 2010 and 2017 were included. Data was collected on patient and infection characteristics. The primary treatment aim was successful infection control without the use of antibiotic therapy afterwards. Infection-free survival analysis was performed using the Kaplan–Meier method with type of periprosthetic joint infection-related revision as covariate. Within the group of 2-stage revisions, use of an antibioticfree window was selected as covariate.Results: 128 patients were treated for a periprosthetic joint infection-related revision procedure (81 hips and 47 knees). Successful infection control was achieved in 18 of 21 cases for the 1-stage and 89 out of 107 cases for the 2-stage revision procedure (83%) respectively after follow-up of more than 4 years. In addition, 2-stage revision procedure infection control was achieved in 52 of 60 cases with an antibiotic-free interval and 37 of 45 cases without such interval (p = 0.6). The mean infection-free survival of the 1-stagerevision was 90 months (95% CI 75–105) and 98 months (CI 90–106) for the 2-stage revision procedure.Interpretation: There seems to be no difference in infection control and infection-free survival between the 1- and 2-stage revision procedure. Second, an antibiotic-free window in the case of a 2-stage revision did not seem to influence treatment outcome. However, one must be cautious when interpreting these results due to confounding by indication and the small study population. Therefore, no definite conclusion can be drawn.
Larger 5-year migration but similar polyethylene wear of cementless hemispherical cups with electrochemically applied hydroxyapatite (BoneMaster) coating compared with porous plasma-spray titanium: a randomized 5-year RSA study
Authors: Breddam Mosegaard Sebastian , Jørgensen Peter Bo , Storgaard Jakobsen Stig , Daugaard Henrik , Søballe Kjeld , Stilling Maiken
Published: July 2022

Background and purpose: BoneMaster (BM) is a thin electrochemically applied hydroxyapatite (HA) implant coating marketed with expectations of improved osseointegration properties but less polyethylene (PE) wear. We compared the midterm cup migration and PE wear of cementless porous-coated hemispherical cups with and without BM.Patients and methods: In this patient-blinded, randomized controlled trial, 53 patients with a mean age of 64 years (55–75) received total hip arthroplasty with a porous-coated (P) or porous and BoneMaster (PBM) coated Exceed cup and ArCom E1 infused PE. Patients were followed with RSA, Hip Osteoarthritis Outcome Score (HOOS), and Euro-Qol-5-3L (EQ-5D) at 3 and 6 months, and 1-, 2-, and 5-yearfollow-up.Results: At 5-year follow-up, total translation and maximum total point motion was 0.28 mm (95% CI 0.08; 0.47) and 0.52 mm (CI 0.12; 0.93) higher in the PBM group than in the P group. PE wear was comparable between PBM and P cups, and 2D wear rate from 1-year follow-up to last follow-up was 0.03 mm (CI 0.02–0.03). The 5-year anterior translation was 0.05 mm (CI –0.10 to 0.21) in the normal BMD group and 0.40 mm (CI 0.22–0.57) in the osteopenia group.Interpretation: At 5-year follow-up, Exceed cups in the PBM group migrated more than in the P group but the PE wear rate was low and similar. This study does not indicate any advantage of additional BoneMaster coating compared with porous coating alone on cementless hemispherical cups with regards to migration, polyethylene wear, and clinical outcomes.
Opioid prescribing patterns after arthroplasty of the knee and hip: a Dutch nationwide cohort study from 2013 to 2018
Authors: Van Brug Heather E , Nelissen Rob G H H , Lijfering Willem M , Van Steenbergen Liza N , Rosendaal Frits R , Van Dorp Eveline L A , Bouvy Marcel L , Dahan Albert , Gademan Maaike G J
Published: July 2022

Background and purpose: Numbers on opioid prescriptions over time in arthroplasty patients are currently lacking. Therefore we determined the annual opioid prescribing rate in patients who received a hip/knee arthroplasty (HA/KA) between 2013 and 2018.Patients and methods: The Dutch Foundation for Pharmaceutical Statistics, which provides national coverage of medication prescriptions, was linked to the Dutch Arthroplasty Register, which provides arthroplasty procedures. The opioid prescription rates were expressed as the number of defined daily dosages (DDD) and morphine milligram equivalent (MME) per person year (PY) and stratified for primary and revision arthroplasty. Amongst subgroups for age (< 75; ≥ 75 years) and sex for primary osteoarthritis arthroplasties, prescription rates stratified for opioid type (weak/strong) and prevalent preoperative opioid prescriptions (yes/no) wereassessed.Results: 48,051 primary KAs and 53,964 HAs were included, and 3,540 revision KAs and 4,118 HAs. In 2013, after primary KA 58% were dispensed ≥ 1 opioid within the first year; this increased to 89% in 2018. For primary HA these numbers increased from 38% to 75%. In KAs the prescription rates increased from 13.1 DDD/PY to 14.4 DDD/PY, mainly due to oxycodone prescriptions (2.9 DDD/PY to 7.3 DDD/PY), while tramadol decreased (7.3 DDD/PY to 4.6 DDD/PY). The number of MME/PY also increased (888 MME/PY to 1224 MME/PY). Similar changes were observed for HA and revision arthroplasties. Irrespective of joint, prescription of opioid medication increased over time, with highest levels in groups with preoperative opioid prescriptions while weak opioid prescriptions decreased.Interpretation: In the Netherlands, between 2013 and 2018 postoperative opioid prescriptions after KA and HA increased, mainly due to increased oxycodone prescriptions with highest levels after surgeries with preoperative prescriptions.
Optimal Timing of Intravenous Acetaminophen Administration for Postoperative Analgesia
Authors: Shinoda Maho , Nishimura Akiko , Sugiyama Erika , Sato Hitoshi , Iijima Takehiko
Published: July 2022

Objective:

Acetaminophen (APAP) is widely used as an analgesic for postoperative pain relief. However, the pharmacokinetic-pharmacodynamic (PK-PD) properties of intravenous APAP administration remain unclear. We developed a PK-PD model in adult volunteers.

Methods:

APAP (1 g) was intravenously administered to 15 healthy volunteers. The pain equivalent current (PEC) was then measured using the pulse current, corresponding to the quantitative value of pain perception. The PK model was developed using a 2-compartment model, and the PD model was developed using a linear model and an effect compartment model.

Results:

APAP plasma concentration peaked just administration, whereas PEC significantly increased at 90 minutes and lasted through the experimental period (300 minutes). APAP plasma concentrations and PEC were processed for use in the PK-PD model. The developed PK-PD model delineates the analgesic effect profile, which peaked at 188 minutes and lasted until 327 minutes.

Conclusion:

We developed the PK/PD model for APAP administered intravenously. The analgesic effect can be expected ∼90 minutes after administration and to last >5 hours. It is suggested that APAP be administered ∼90 minutes prior to the onset of anticipated postoperative pain.
Implications of Electronic Cigarettes on the Safe Administration of Sedation and General Anesthesia in the Outpatient Dental Setting
Authors: Heller Zachary A. , MS Edward C. Adlesic , DMD Jason E. Portnof
Published: July 2022

Today the number of electronic cigarette users continues to rise as electronic cigarettes slowly, yet steadily overtake conventional cigarettes in popularity. This shift is often attributed to the misconception that electronic cigarettes are “safer” or “less dangerous” than conventional cigarettes. Recent studies have shown that electronic cigarettes are far from safe and that the inhaled agents and byproducts within vaping aerosols can have adverse effects on systemic and oral health like combustible tobacco products. The first electronic cigarettes were originally introduced as a tool for smoking cessation. However, newer iterations of electronic cigarette devices have been modified to allow the user to consume tetrahydrocannabinol (THC), the psychoactive component of cannabis, in addition to nicotine. As the popularity of these devices continues to rise, the number of patients seeking dental treatment who also consume electronic cigarettes will too. This article aims to shed light on the deleterious effects electronic cigarettes can have on systemic and oral health, as well as the special considerations for sedation and anesthesia providers treating patients who use electronic cigarettes.
Decision Support System for Determining Flood Evacuation Locations in Kabupaten Bandung Using the Simple Additive Weighting (SAW) Method
Authors: Angesti Rani Gusti , Ramadhan Arieftyarto Taufik , Hanifah Fifin Nur , Agustina Grace , Rizana Afrin Fauzya , Kurniawati Amelia
Published: July 2022

West Java Province is one of the provinces with the most flood disasters, which is 863 times and the highest number of floods occurred in Kabupaten Bandung is 228 times. Because floods often occur in Kabupaten Bandung make BPBD (Badan Penanggulangan Bencana Daerah) must respond to this problem, including by choosing a quick evacuation location. Choosing an appropriate evacuation route is very helpful in reducing losses and especially saving people's lives. So we need a computer-based system that can help BPBD in determining which location is most suitable as an evacuation location in Kabupaten Bandung by using the SAW (Simple Additive Weighting) method. This method is a simple weighting method or additional weighting to solve problems in a decision support system. The results of this study are a rank of recommendations for evacuation locations in Kabupaten Bandung. To test the feasibility and suitability of the system, a BlackBox test and user acceptance test was carried out.
Method of Selecting Gloves Based on Pressure on The Palms Using A Measuring Instrument with A Force Sensing Resistor
Authors: Widodo Ranu Tri , Herdiman Lobes , Susmartini Susy
Published: July 2022

Assembly is a common activity in manufacturing companies. The use of handtools during assembly creates pressure on the palms surface which can lead to injury. To reduce the risk of injury, operators need to use gloves as personal protective equipment. Regardless of the general function of the glove, the type of glove tends to be chosen specifically for each task. But there is no specific method to determine the right gloves for certain activities. It is important to know the effect of using gloves on the palms surface during work activities. So this study aims to design a measuring instrument that can determine the pressure on the palm surface during activities by wearing gloves. This is done in order to be able to choose the right gloves for assembly. The result shown that during assembly the areas on the palms receive different pressure. Areas of the palms that receive the greatest pressure are the distal phalanx, and proximal phalanx on the index, middle, ring and little fingers. Pressure on the palms surface differs depending on the type of glove used. This may be due to the thickness of the glove, the thinner the glove, the greater the pressure on the palms surface. Assembling the chair using leather gloves has the lowest pressure value compared to other gloves. The pressure value on the palms surface when wearing leather gloves during the assembly of the chair is 262.15 N, 40% lower than the assembly without using gloves.
Modeling Underlying Pattern Making Construction Safety Risk Mitigation Decisions Using Dynamic Systems
Authors: Munang Aswan , Nurisusilawati Isnaini
Published: July 2022

The Occupational Health and Safety Management System (SMK3) is one of the factors that must be always monitored during the implementation of construction in achieving the success of project objectives. The implementation of SMK3 and decision-making still comes from project actors with different levels of experience gaps, causing the decisions taken to be less systematic and affecting the productivity of project performance. The purpose of the research is to conduct risk management simulations to increase insight into risk management and mitigation as a support for appropriate decision making in supporting project productivity, quality, and cost.Risk identification process through brainstorming, interviews, and observations with competent resource persons and project actors who have more than 5 years of experience in railway projects. Risk identification generates parameters and measures project risk by processing data using SPSS V23 software and dynamic simulation using Vensim PLE software. Simulation shows that there is a decrease in risk parameters in design and technology by -6.29%, construction management -5,12%, work safety and environment -5,90%, materials and equipment 3,37% and logistics -6,23%. Management of SMK3 by combining methods can increase accuracy in making risk mitigation decisions and can improve and understand the complexity of overall risk management performance from time to time.
Solving the Capacitated Vehicle Routing Problem with Heterogeneous Fleet Using Heuristic Algorithm in Poultry Distribution
Authors: Kasanah Yulinda Uswatun , Qisthani Nabila Noor , Munang Aswan
Published: July 2022

The problem that is often experienced in the delivery of goods from distributor to the destination is the delivery route that is not sufficient with the vehicle's capacity. This matter is crucial because it can affect the clients' trust on the shippers in the distributor. This problem can be analyzed using Capacitated Vehicle Routing Problem (CVRP) with Clarke and Wright Algorithm. This research begins with determining the distance between all coordinates with Euclidean Distance, making the distance matrix between places to go. After that, the calculation CVRP using Clarke and Wright Algorithm is exected in this study, a calculate CVRP using Clarke and Wright algorithm can help of Python. The study was conducted at 16 customers coordinates, the results obtained by 4 routes with total load 4751 kg and distance 436 km. Route of delivery the first route 924 kg load and distance 80 km, second route 962 kg load and distance 112 km, third route 1450 kg load and distance 144 km, and the fourth route 1415 kg load and distance 100 km.
Digitálna komunikácia slovenských miest
Authors: Rojíková Darina , Lisková Laura
Published: July 2022

Based on a theoretical overview, the work defines digital forms of marketing communication and possibilities of their use in the environment of local governments. The aim of the paper is to identify the role and extent of the use of digital forms of marketing communication in the conditions of Slovak regional cities. The research sample consists of 8 Slovak regional cities (Banská Bystrica, Bratislava, Košice, Nitra, Prešov, Trenčín, Trnava, Žilina). We used data obtained from primary research to process the paper. The research was carried out by the method of questioning, in the form of questionnaires. The results of the analysis point to gaps and differences in the use of individual digital forms of marketing communication by Slovak regional cities. The conclusion of the article summarizes the research results and points out the opportunities and pitfalls of implementing digital forms of marketing communication in the environment of Slovak regional cities.
Fiscal decentralization and public debt: New evidence from EU countries
Authors: Mali Siniča , Maličká Lenka
Published: July 2022

The aim of the paper is to examine the relationship between fiscal decentralization and government debt of EU countries with respect to EU accession, country size and number of government levels in the period of 1999 – 2019 using panel data models based on six various estimators. The differences regarding the effect of fiscal decentralization on government debt were estimated on the basis of the seemingly unrelated regression (SUR). The research results have shown the following: 1. The effect of fiscal decentralization on public debt is statistically significant. 2. Fiscal decentralization has negatively affected public debt of EU member states in the observed period. 3. The direction and intensity of the effect of fiscal decentralization on public debt depends on the size of the country (measured by the number of its inhabitants), the number of government levels and the year of the country’s accession to the EU.
Hepatocellular Carcinoma: Aetiology and Mechanisms of Development. A Literature Review
Authors: Menshikov K. V. , Sultanbaev A. V. , Musin Sh. I. , Rakhmatullina I. R. , Menshikova I. A. , Abdeev R. R. , Sultanbaeva N. I. , Popova E. V. , Serebrennikov G. A.
Published: July 2022

Liver cancer remains a global challenge of healthcare, with the incidence growing worldwide. According to various authors, over 1 million patients will be diagnosed with liver cancer each year by 2025. The molecular pathogenesis of HCC varies with respect to genotoxic lesions and aetiologies. Although our understanding of the HCC pathophysiology and drivers tends to improve, it is still distant from translation into clinical practice. About 25 % of HCC cases are associated with variant mutations. HCC pathophysiology is a complex multi-step process. The interaction of various factors underlies the early stages of malignant hepatocyte transformation towards the development of HCC. Overall, about 20–25 % of HCC patients have at least one potential driver mutation. Obesity should also be noted as being associated with a higher risk of HCC and various other cancers. Despite many issues in the HCC pathogenesis being already known, the unresolved questions remain. Modern molecular genetic diagnostics and animal modelling of malignant tumours are expanding our horizons of knowledge in this field.
Ultra-Mini Percutaneous Nephrolithotripsy and Retrograde Intrarenal Surgery in Treatment of Less than 2 cm Kidney Stones: Comparative Efficacy and Safety
Authors: Seregin I. V. , Seregin A. A. , Filimonov E. V. , Shustitskiy N. A. , Morozov A. D. , Sinyakova L. A. , Loran O. B.
Published: July 2022

Background. Renal stones of ≤ 2cm size occur most commonly, with several treatment options currently available that include remote shockwave lithotripsy, percutaneous nephrolithotripsy (PCNL) and retrograde intrarenal surgery (RIRS). The choice of treatment for ≤ 2 cm kidney stones remains a relevant and hotly debated issue.

Aim. A study of the efficacy, safety, advantages and disadvantages of ultra-mini percutaneous nephrolithotripsy (ultra-mini PCNL) and retrograde intrarenal surgery (RIRS) in treatment of ≤ 2 cm kidney stones.

Materials and methods. Treatment outcomes in urology patients of the Botkin Hospital were analysed retrospectively for years 2017–2022. The patients were divided between cohorts: cohort 1 consisted of patients who underwent ultra-mini PCNL; cohort 2 included 41 patients with RIRS.

Results and discussion. The incidence of complete stone absence on the day after surgery was significantly higher in cohort 1 (39; 92.8 %) vs. 2 (33; 80.4 %). Mean operation time was significantly less in cohort 1 (55 [30–80] min) vs. 2 (78 [30–125] min). Mean hospital stay did not differ significantly between the cohorts: 3 (1–5) vs. 2.8 (2–4) days in cohorts 1 and 2, respectively. Haematuria was statistically more severe in cohort 1 (7 cases; 16.6 %) vs. 2 (4 cases; 9.7 %); mean postoperative haemoglobin decrease was also significantly higher in cohort 1 (11.6) vs. 2 (6.4 g/L).

Conclusion. Both ultra-mini PCNL and RIRS are effective, safe and complementary procedures in treatment for ≤2 cm renal stones. Ultra-mini PCNL is more effective over RIRS in terms of single-intervention complete stone removal and shorter operation time, whereas the overall complications rate did not significantly differ between cohorts.
PERANCANGAN APLIKASI PENGOLAHAN DATA PEMBAGIAN TUGAS MENGAJAR GURU PADA SMP NEGERI 1 PUNGGUR
Authors: Siswanto Siswanto , Mujito Mujito , Pujianto Pujianto
Published: July 2022

Untuk menjamin lancarnya proses belajar mengajar diperlukan adanya pembagian tugas mengajar guru yang dapat menentukan pekerja dalam melaksanakan tugas nya sehingga terlaksana dengan baik. Sebagai contoh adanya rambu-rambu lalu lintas dijalan yang memberikan petunjuk jalan arah mana yang di tuju, dimana kita kita dapat memarkirkan kendaraan, bilaman kita boleh melewati jalan pada waktu tertentu yang bertujuan memberikan kemanan dan kenyamanan berlalu lintas. Penelitian menggunakan metode pengolahan data berupa observasi, interview, dan dokumentasi. Sedangakan metode perancangan sistem informasi menggunakan Bagan Alir Dokumen, Data Flow Diagram, Entity Relationship Diagram. Sofware pendukung dalam pembuatan aplikasi pengolahan data pembagian tugas mengajar guru ini menggunakan Visual Basic 6.0 dan database yang digunakan adalam Microsoft acces. Perancangan aplikasi pengolahan data pembagian tugas mengajar guru menghasilkan rancangan berupa rancangan database/basis data yaitu tabel Guu, tabel Tugas Mengajar, tabel Matapelajaran, Tabel Tugas Mengajar, Entity Relationship Diagram (ERD) dan Relasi antar tabel. Dengan adanya aplikasi pengolahan data pembagian tugas mengajar guru yang dirancang oleh penulis, diharapkan dapat memperbaiki pengolahan data pembagian tugas mengajar guru pada SMP Negeri 1 Punggur dalam pengolahan, pencarian dan pembuatan laporan sehingga mendapatkan hasil yang akurat dan tepat waktu.