bluuebunny/crossref_metadata_2025 huggingface dataset:
Program Kelas Ibu Hamil Sebagai Upaya Pencegahan Komplikasi Kehamilan Di Puskesmas Sokaraja II
Authors: Mu'minah Ikhwah , Nur Azizah Atika
Published: November 2023

According to Law No. 36 of 2009 on health, one of the efforts to improve maternal health aims to maintain the health of mothers and children and reduce maternal mortality. The government's efforts to achieve this goal are to improve midwifery services and disseminate health of both mother and childbooks. One of the efforts to provide midwifery services is a class for pregnant women. Pregnant mothers class is a means of learning together about health for pregnant women in the form of face-to-face groups which aims to increase the knowledge and skills of mothers regarding pregnancy, childbirth, postpartum care, baby care, infectious diseases. In qualitative research with a phenomenological descriptive approach. The results of the study can be concluded that the participation of pregnant women in the class of pregnant women is strongly influenced by factors of education, knowledge and work. The occupational factor is the biggest obstacle for pregnant women where mothers who work as laborers rarely attend pregnant women classes because the schedule for carrying out classes for pregnant women and working schedules is not appropriate.
PENGARUH PENGGUNAAN ERYTHIRNA SUBUMBRANS MERR ( DAUN DADAP SEREP) SEBAGAI ALTERNATIF PENANGANAN BENDUNGAN ASI PADA IBU MENYUSUI
Authors: Rahmawati Dechoni , Dewi Anggraeni Fatimah
Published: November 2023

Background: Breast milk dam is a condition commonly experienced by breastfeeding mothers that can cause pain and complaints in the

                                         breast. There are several traditional medicines that are believed to  

help overcome breast milk dams, one of which is Erythrina subumbtans. However, there are still few studies that prove the effectiveness of Erythrina subumbtans in treating breast milk dams in nursing mothers (Amalia, 2019).

Research Objective: The purpose of this study was to determine the effect of using Erythrina subumbtans as a traditional medicine to treat breast milk dams in nursing mothers.

Research Method: This study will use a pre-post test design with a sample of 20 breastfeeding mothers suffering from breast milk dams. Then, they will be divided into two groups, namely the intervention group that will be given Erythrina subumbtans and the control group that is not given the drug. The data collected will be analyzed using statistical tests with a significance level of 5%

The location of this study is in the working area of Puskesmas Sedayu 2, Bantul, Yogyakarta with a sample of 20 respondents and Total Sampling sampling techniques. The data analysis technique used in this study was Wilcoxon.

Research Results: There is an influence of the use of Erythirna Subumbrans Merr ( spare dadap leaves) as an alternative to breast milk dam treatment in breastfeeding mothers indicated by a p-value of

0.004 where the p-value is smaller than the significance value with an error rate of 5% (0.05). This shows that there is an effect of using Erythirna subumbrans Merr (spare dadap leaves) as an alternative to breast milk dam treatment in nursing mothers
SELF EFFICACY AKSEPTOR KB TERHADAP ALAT KONTRASEPSI DENGAN PEMILIHAN KB MKJP DAN NON MKJP
Authors: Noviani Aris , Anggraini Yeni
Published: November 2023

The low utilization of KB MKJP (Long Term Contraceptive Method) is one of the main problems in the Family Planning program. Acceptors' wrong assumptions about KB MKJP can result in incompatibility of acceptors in using contraception. Self-efficacy is also an internal factor that influences the views or perceptions of an acceptor in choosing the type of family planning. This study used a cross-sectional design using the Yate's Correction test. This study aims to analyze the relationship between the self-efficacy of contraceptive use and the selection of KB MKJP and Non-MKJP. The sampling technique used was purposive sampling. The sample in this study were couples of childbearing age (PUS) aged 15-49 years who used contraception, totaling 35 respondents. The results showed that there was a significant relationship between the self-efficacy of family planning acceptors on the selection of MKJP and Non-MKJP KB, with a p-value <0.05. The participation of all levels of society needs to be increased to reduce dropout rates and increase the use of long-term contraceptives.
Stimulasi Kutaneus Slow Stroke Back Massage Terhadap Nyeri Dismenorea Primer Di Klaten
Authors: Rohmawati Wiwin , Hartati Lilik
Published: November 2023

Menstruation is the process of releasing the uterine wall accompanied by bleeding and occurs repeatedly every month. There are still many adolescents who experience menstrual problems such as menstrual pain or dysmenorrhoea during menstruation. Primary dysmenorrhoea is menstrual pain without abnormalities in the reproductive organs caused by contractions of the uterine wall. There are two types of therapy to treat dysmenorrhoea, namely pharmacological and non-pharmacological therapy. Non-pharmacological therapy is wrong one is the cutaneous stimulation of the Slow Stroke Back Massage. This study aims to determine the effect of cutaneous stimulation Slow Stroke Back Massage on the level of primary dysmenorrhoea pain at the Putri Aisyiyah Tonggalan Klaten Orphanage.This type of research is pre-experimental with a one group pretest-posttest research design. The population in this study was 48 young women at the Putri Aisyiyah Tonggalan Klaten Orphanage in April 2017, with a sample of 33 adolescents using purposive sampling technique. Data analysis used the Wilcoxon signed rank test. The statistical test results with the Wilcoxon signed rank test (p <0.005) obtained the sig value. (2-tailed) of 0,000.The conclusions in this study indicate that there is an effect of cutaneous stimulation of Slow Stroke Back Massage on the level of primary dysmenorrhoea pain at the Putri Aisyiyah Orphanage at Tonggalan Klaten. Adolescents should always perform cutaneous stimulation of Slow Stroke Back Massage every menstrual cycle so that the pain level of primary dysmenorrhea can be reduced.
Hubungan Lingkar Kepala Dengan Prestasi Belajar Pada Anak SD N 1 Tambongwetan Kalikotes
Authors: Uswatun Anna
Published: November 2023

Brain growth is one of the things that changes, if nutritional intake is reduced, some parts of the brain development will be disrupted. The result of malnutrition will result in obstruction of the body and brain development, where head circumference is used as a parameter to determine it. In the growth parameters, there are several body parts that are measured including body weight, height, head circumference and chest circumference, if there is one that is less than normal it can affect learning achievement. The purpose of this study was to find out "the relationship between head circumference and learning achievement in SD N 1 Tambongwetan children".

This study used an analytic survey method with a cross sectional design. The research population comprised all grade 1 and 2 students at SD N 1 Tambongwetan as many as 46 students. Sampling using total sampling. Data analysis using Kendall Tau. The results of data analysis showed ???? = 0.337 with a P value = 0.016; P value <0.05.

The conclusion of the results of this study is that there is a relationship between head circumference and learning achievement in SD N 1 Tambongwetan children. Suggestion to parents should always pay attention to their children's nutritional intake because adequate nutrition can affect the growth of body size including head circumference.
PENGARUH ISAP LENDIR (SUCTION) SISTEM TERBUKA TERHADAP SATURASI OKSIGEN PADA PASIEN TERPASANG VENTILATOR
Authors: Zukhri Saifudin , Suciana Fitri , Herianto Agus
Published: November 2023

Patients who are attached to endotracheal tube and ventilator will requiring endotracheal tube suctioning that can causes hypoxemia. In ICU RSUP dr. Soeradji Tirtonegoro, the open endotracheal tube suctioning was performed using a general suctioning SOP. Credland has developed an open endotracheal tube suctioning procedure based on recent literature and research. The aim of this research is to know the difference of the effect of open endotracheal tube suctioning that done in ICU with open endotracheal suctioning by Credland on the peripheral oxygen saturation of the patient who installed ventilator.This research uses “quasi experiment” design with “pre test and post test nonequivalent control group” and uses “consecutive sampling”. Ten respondents became the control group when an open endotracheal tube suctioning was applied using generalized SOP in ICU and became the treatment group when was applied with the Credland method. Statistical analysis to determine the peripheral oxygen saturation difference in each group using “wilcoxon”. To compare the oxygen peripheral saturation difference in the control group and the treatment group using “mann whitney”. In the control group the mean of oxygen peripheral saturation before suctioning was 97.8 ± 2.4 and after suction was 94.2 ± 3.0 with the mean difference before and after the suctioning was 3.6 ± 1 , 5. In the treatment group the mean of oxygen peripheral saturation before suctioning was 97.4 ± 3.2 and after suctioning was 95.7 ± 4.9 with average saturation difference before and after suctioning was 1.7 ± 2, 2.There was a difference in the effect of an open endotracheal tube suctioning that done in ICU with open endotracheal tube suctioning by Credland’s methode on the peripheral oxygen saturation of the ventilator-installed patient with p value = 0.014 (p <0.05)
PERBANDINGAN HONEY DRESSING TERHADAP JENIS DRESSING LAINNYA DALAM PROSES PENYEMBUHAN LUKA PADA PASIEN DENGAN ULKUS DIABETIK
Authors: Maulana Muhammad Sobri
Published: November 2023

Ulkus kaki diabetik merupakan komplikasi yang menyebabkan morbiditas tertinggi pada pasien dengan DM. Tata laksana dari ulkus kaki diabetik ialah dengan 6 kontrol dimana salah satunya ialah kontrol luka dengan dilakukan debridement dan dressing. Pilihan dressing yang tepat akan membuat penyembuhan luka menjadi lebih baik cepat dan efektif. banyak cara yang dapat digunakan sebagai dressing, namun cara dressing mana yang lebih baik digunakan untuk perawatan ulkus diabetik masih belum jelas. atas pertimbangan efektivitas biaya, perlu dilakukan pencarian laporan kasus berdasarkan bukti mengenai efektivitas penggunaan honey dressing dibandingkan dengan dressing jenis lainnya. Pencarian literatur dilakukan pada database online yaitu , EBSCO, Cochrane, Pubmed, dan Scopus, sciendirect, proquest.  Artikel terpilih ditelaah dengan metode Oxford Center for Evidence Based Medicine. Didapatkan 1 studi sistematik review yang relevan dengan pertanyaan klinis yang diajukan. Honey dressing menjadikan lama terapi lebih singkat 1,28 hari dibandingkan dengan kontrol. honey dressing menjadikan mean purge time lebih singkat 0,92x dibandingkan dengan kontrol. honey dressing menjadikan germ purge ratio lebih cepat 1,63x dibandingkan dengan kontrol. honey dressing menjadikan laju penyembuhan luka lebih lama 1,05x dibandingkan dengan kontrol honey dressing menjadikan luas area yang sembuh lebih 1,45x luas dibandingkan dengan kontrol. Perawatan luka dengan menggunakan honey dressing pada pasien ulkus diabetik lebih baik dibandingkan dengan dressing jenis lain masih kurang sehingga diperlukan lebih banyak penelitian mengenai topik tersebut.
PENERAPAN TEKNIK FISIOTERAPI DADA TERHADAP KETIDAKEFEKTIFAN BERSIHAN JALAN NAFAS PADA ANAK DENGAN PENYAKIT SISTEM PERNAFASAN
Authors: Pangesti Nova Ari , Riski Setyaningrum
Published: November 2023

Respiratory disease is a condition where there is a problem in respiratory system. Some of disease include in respiratory disease are pneumonia, asthma, and bronchitis. Child who experience respiratory tract disorders often occur an increase in the production of excessive phlegm in the lungs of phlegm which thicknes and accumulates so that it is difficult to remove, therefore to help speed healing assisted by chest physiotherapy. The aim is to know the effect of chest physiotherapy on ineffective of clearance airway on a child with respiratory disorders. This research use literature review as method to know the effect of chest physiotherapy. The result of research After performing chest physiotherapy, airway clearance of child effectively with the criteria for respiratory frequency within normal limits, being able to remove sputum, no additional breath sounds, and coughing decreased. Chest physiotherapy are significantly effective to overcome ineffective airway clearance.
HUBUNGAN POLA ASUH ORANG TUA DENGAN SIBLING RIVALRY PADA ANAK USIA 3-6 TAHUN DI BA AISYIYAH SENTONO
Authors: Hartati Lilik , Qoyyimah Anna Uswatun
Published: November 2023

Pola asuh orang tua merupakan salah satu faktor yang mempengaruhi sibling rivalry pada anak usia 3-6 tahun. Sebanyak 64,3% anak mengalami sibling rivalry. Tujuan penelitian ini adalah untuk mempelajari pengaruh pola asuh orang tua dengan kejadian sibling rivalry pada anak usia 3-6 tahun di BA Aisyiyah Sentono.

Penelitian ini menggunakan metode analitik observasional dengan pendekatan cross sectional pada bulan Maret 2020. Responden adalah orang tua siswa/i BA Aisyiyah Sentono. Jumlah sampel dengan total sampling sebanyak 35 orang tua. Variabel independen yang diteliti yaitu pola asuh orang tua sedangkan variabel dependen adalah sibling rivalry pada anak usia 3-6 tahun. Pengumpulan data menggunakan kuesioner. Analisis menggunakan uji Chi Square (X2) dengan α = 0,05Hasil penelitian menunjukkan pola asuh otoriter 30%, demokratis 32%, permisif 11,8%, dan pasif 26,2%. Sebagian besar anak usia 3-6 tahun mengalami sibling rivalry sebanyak 24 (64,3%) dan yang tidak sebanyak 11 (35,7%) anak. Jenis pola asuh mempunyai hubungan bermakna dengan sibling rivalry pada anak usia 3-6 tahun. Hasil uji analisis didapatkan hasil p = 0,000 (p ≤ 0,05) dengan nilai koefisien kontingensi sebesar 0,651 maka H0 ditolak dan H1 diterima yang berarti mempunyai hubungan yang kuat.Kesimpulan penelitian ini adalah terdapat hubungan yang signifikan antara pola asuh orang tua dengan sibling rivalry pada anak usia 3-6 tahun di BA Aisyiyah Sentono dimana penerapan pola asuh yang tepat pada anak sangat penting untuk mencegah timbulnya kejadian sibling rivalry dalam keluarga di BA Aisyiyah Sentono
PROFIL TERAPI IMUNOSUPRESAN PADA PASIEN ANAK DENGAN LUPUS NEFRITIS
Authors: Aghnia Fuadatul Inayah  , Lilik Yusetyani  , Putra Adi Purnama  , Nabilah Utari
Published: November 2023

Lupus nefritis merupakan komplikasi serius dari systemic lupus erythematosus (SLE) dan menyerang organ ginjal. Lupus nefritis adalah penyakit autoimun yang awalnya dimediasi oleh autoantibodi kemudian membentuk ikatan antara kompleks imun dengan jaringan sehingga menyebabkan organ dan sel mengalami kerusakan. Lupus nefritis ditandai dengan munculnya proteinuria yang persisten. Sebanyak 37-82% pada anak-anak dengan SLE berkembang menjadi lupus nefritis. Target terapi pasien SLE adalah mencegah terjadinya kekambuhan dan kerusakan organ serta meminimalisir efek samping obat. Mencegah kekambuhan pada pasien SLE perlu diberikan obat-obat imunosipresif yang menekan disregulasi sistem imun. Pemberian terapi imunosupresan berupa steroid, MMF dan klorokuin terbukti aman. Pemberian metilprednisolon dengan dosis sangat tinggi hingga 1000 mg sehari secara intravena bertujuan untuk menekan aktivitas sel imun. Tidak hanya itu, pemberian terapi imunosupresan secara kombinasi memberikan mempercepat proses remisi, seperti dengan pemberian MMF dan klorokuin yang sudah terbukti aman. MMF dengan dosis hingga 1g/hari memberikan efektivitas yang baik. Sementara klorokuin, telah disetujui FDA sebagai terapi lupus nefritis yang sebelumnya sering digunakan sebagai antimalaria. Klorokuin dilaporkan dapat mencegah kerusakan ginjal dengan menekan kerja dari sel-sel imun.
HUBUNGAN PENGETAHUAN KELUARGA DENGAN UPAYA PENCEGAHAN CHIKUNGUNYA
Authors: Endang  Sawitri  , Fitri Suciana  , Ridwan M  , Daryani
Published: November 2023

Abstrak

 

Latar Belakang : Dewasa ini masih dihadapkan dengan meningkatnya beberapa penyakit menular (re-emerging diseases). Penyakit menular yang masih menjadi perhatian dan masalah kesehatan masyarakat di Indonesia antara lain Demam Chikungunya yang penyebarannya semakin luas. mencegah terjadinya KLB Chikungunya dengan memotivasi dan memberikan penyuluhan  tentang  kesehatan untuk meningkatkan pengetahuan keluargat. Metode : penelitian ini menggunakan desain survei analitik dengan pendekatan waktu cross-sectional. Populasi penelitian ini adalah kepala keluarga Dukuh Krajan Kecamatan Jatinom. Jumlah sampel penelitian sebanyak 53 sampel yang diambil secara total sampling. Istrumen pengumpulan data menggunakan kuesioner. Analisa data pada analisis bivariat menggunakan uji Kendall Tau. Hasil: Hasil penelitian di Dukuh Krajan Kecamatan Jatinom menunjukan dari 53 responden,  30 responden (56,6%) melakukan upaya pencegahan. Hasil uji Kendall Tau menunjukan tidak ada hubungan antara pengetahuan keluarga dengan upaya pencegahan chikungunya (ρ>0,05). Kesimpulan : pengetahuan keluarga  tidak berhubungan dengan upaya pencegahan chikungunya

Kata kunci : pengetahuan keluarga , pencegahan chikungunya
GAMBARAN PENGETAHUAN REMAJA TENTANG PENDIDIKAN SEKS
Authors: Puput Risti Kusumaningrum  , Chori Elsera  , Riskawati
Published: November 2023

Pendidikan seks untuk remaja membahas seputar gambaran biologi organ reproduksi, masalah hubungan, seksualitas, kesehatan reproduksi, dan penyakit menular seksual. Penyebab permasalahan remaja yang utama adalah kurangnya informasi yang benar terkait seks, begitupun pada siswa remaja di SMA N 3 Klaten belum mendapat sosialisasi terkait pendidikan seks. Maka dari itu perlu dilakukan penelitian tentang bagaimana gambaran pengetahuan remaja tentang pendidikan seks. Tujuan penelitian untuk mengetahui gambaran pengetahuan remaja tentang pendidikan seks. Metode penelitian ini menggunakan metode deskriptif kuantitatif. Sampel yang digunakan sebanyak 200 responden. Teknik pengambilan sampel adalah metode non probability sampling dengan pendekatan purposive sampling. Hasil penelitian ini menggambarkan jenis kelamin didominasi oleh perempuan sejumlah 128 responden (64%), usia 16 tahun sejumlah 141 responden (70.5%), pekerjaan orang tua buruh 73 responden (36.5%). Responden yang memiliki pengetahuan baik tentang pendidikan seks sejumlah 165 responden (82.5%), cukup sejumlah 30 responden (15%), dan kurang sejumlah 5 responden (2.5%). Kesimpulan penelitian tentang Gambaran Pengetahuan Remaja Tentang Pendidikan Seks adalah berpengetahuan baik yaitu 165 responden (82.5%).
PENGARUH SOCIAL ACTIVITY PROBLEM DAN SOCIAL NETWORK PROBLEM TERHADAP SOCIAL ENGAGEMENT DAN DAMPAKNYA PADA GANGGUAN KOGNITIF LANSIA
Authors: Hendri Kurniawan
Published: November 2023

Gangguan kognitif menjadi salah satu permasalahan utama pada lansia. Upaya lansia untuk menjaga jaringan sosial (social network) dan berpartisipasi dalam aktivitas sosial (social activity) disinyalir berkaitan dengan permasalahan kognitif yang dialaminya. Tujuan penelitian adalah mengkaji pengaruh permasalahan aktivitas sosial dan jaringan sosial terhadap keterlibatan sosial (social engagement) dan dampaknya pada gangguan kognitif pada lansia.  Penelitian dilakukan secara observasional dengan desain cross sectional terhadap lansia di Desa Penarukan, Kec. Adiwerna, Tegal. Sampel penelitian berjumlah 45 orang yang diperoleh dengan purposive sampling. Instrumen penelitian menggunakan Index Social Disengagement dan Mini Mental State Examination (MMSE). Data penelitian dianalisis dengan uji regresi logistik biner menggunakan software SPSS 25.  Hasil penelitian menunjukkan mayoritas sampel perempuan (58%), dan umur 60-74 tahun (76%). Hasil uji menunjukkan bahwa lansia dengan gangguan social engagement beresiko meningkatkan gangguan kognitif sebesar 5,091 kali (OR= 5,091, CI95%= 1,319 hingga 19,649, p=0,018.). Lansia dengan permasalahan di aktivitas sosial berisiko mengalami gangguan social engagement lebih besar ((OR= 36, CI95%= 4,024 hingga 322,088, p=0,001.) dibandingkan permasalahan pada jaringan sosial (OR= 5,333, CI95%= 1,453 hingga 19,579, p=0,012.). Permasalahan aktivitas sosial lebih berpengaruh terhadap gangguan social engagement lansia sehingga lebih berisiko 5 kali mengalami gangguan kognitif. Lansia sebaiknya aktif mengikuti kegiatan di masyarakat untuk mengurangi gangguan kognitif.
HANS ABRAHAMSEN’S “LEFT, ALONE” CONCERT AS A GENRE-COMPOSITIONAL AND ARTISTIC PHENOMENON
Authors: Окунева Е.Г. , Томских Д.А.
Published: November 2023

В центре внимания статьи – леворучный фортепианный концерт «Left, alone» (2015) датского композитора Ханса Абрахамсена, посвящённый французскому пианисту Александру Таро. Авторы рассматривают композиционную структуру сочинения, особенности его музыкальной организации и драматургии. Отдельное внимание уделяется художественному замыслу, в котором находят отражение автобиографические черты. В ходе анализа выявляется основная идея сочинения – идея ограничения, которая проявляется на разных уровнях – на уровне организации музыкального материала (краткость тем, ограничение их звукового состава и диапазона), тембровой драматургии (противопоставление оркестрового и солирующего фортепиано) и формы (усечение репризного раздела, применение минималистических приёмов). Авторы приходят к выводу, что идея состязательности, характерная для жанра концерта, в сочинении Абрахамсена переходит в концептуальную сферу, отражая борьбу с жизненными обстоятельствами и стремление преодолеть существующие ограничения.

The focus of the article is the piano concert for the left hand “Left, alone” (2015) by the Danish composer Hans Abrahamsen, dedicated to the French pianist Alexander Taro. The authors examine the structure of the composition, the features of its musical organization and dramaturgy. Special attention is paid to the artistic concept, which reflects autobiographical features. The analysis reveals the main idea of the concert – the idea of constraint, which manifests itself at different levels – at the level of organization of musical material (brevity of thematic material, limitation of its sound composition and range), timbre dramaturgy (opposition of orchestral and solo piano) and form (truncation of the reprise section, the use of minimalist methods). The authors come to the conclusion that the idea of competitiveness, characteristic of the genre of the concerto, in Abrahamsen’s work passes into the conceptual sphere, reflecting the struggle with life circumstances and the desire to overcome existing constraints.
CONTINUING THE CASE OF JOZEF KON: TOUCHES TO THE PORTRAIT OF IRINA BARANOVA
Authors: Копосова И.В.
Published: November 2023

Данная публикация направлена на осмысление фигуры Ирины Николаевны Барановой (1955–2011), педагога и учёного, чья деятельность была безраздельно связана с Петрозаводской консерваторией и оставила в её жизни глубокий след. Предметом изучения в статье стали научные и учебно-методические труды Барановой, а также тексты дипломных работ, выполненных под её руководством. На этой основе охарактеризована сфера научных интересов Ирины Николаевны, дана оценка её наследия, выделены черты научного и педагогического стиля. В целом, деятельность Барановой представлена как наследующая и развивающая характерные черты самобытной научно-педагогической школы, сложившейся в рамках нашего вуза, которая за его пределами интерпретируется как «школа Кона».

This publication is aimed at understanding the figure of Irina Baranova (1955–2011), a teacher and scientist whose activities were completely connected with the Petrozavodsk Conservatoire and left a deep mark on her life. The subject of the study in the article was the scientific and educational-methodical works of Baranova, as well as the texts of theses performed under her supervision. On this basis, the scope of scientific interests of Irina Nikolaevna is characterized, an assessment of her heritage is given, the features of scientific and pedagogical style are highlighted. In general, Baranova's activity is presented as inheriting and developing the characteristic features of an original scientific and pedagogical school that has developed within our university, which is interpreted outside of it as a «Kon school».
ABOUT MODERN MUSIC IN THE PARADIGM OF THE XXI CENTURY (INTERVIEW WITH DOCTOR OF ART CRITICISM VLADISLAV PETROV)
Authors: Соболева Е.А.
Published: November 2023

Данный материал представляет собой интервью с астраханским музыковедом В. О. Петровым, научный интерес которого связан с исследованием музыкального искусства ХХ века. В вопросах, заданных в беседе, были подняты проблемы понятия «современная музыка», синтеза искусств в рамках глобализации и культуры потребления, возникновения эстетики нового типа, в которой красота выражена не в форме и средствах выразительности, а в концепте или идее. Также обсуждался вопрос о сужении круга понимания в тандеме «художник – ценитель», связанного со сложностью и углублением индивидуализации музыкального выражения; рассматривалась перспектива укореняющегося влияния IT-технологий на музыкальное искусство, особенно искусственного интеллекта, как фактора возможной конкуренции между человеком и компьютерной программой в создании не только музыки, но и искусства вообще.

The article is devoted to an interview with Astrakhan musicologist V. O. Petrov, whose scientific interest deals with the study of the musical art of the twentieth century. In the conversation V. O. Petrov expanded on the following issues: the problems of the concept of "modern music", the synthesis of arts within the framework of globalization and consumer culture, the emergence of a new type of aesthetics in which beauty is expressed not in the form and means of expression, but in a concept or idea. The issue of narrowing the circle of understanding in the "artist-connoisseur" tandem related to the complexity and deepening of the individualization of musical expression was also discussed. The prospect of the rooting influence of IT technologies on musical art, especially artificial intelligence, as a factor of possible competition between a person and a computer program in creating not only music, but also art in general was considered.
Concert ACTIVITY OF CHARLES SOUALLE IN THE CONTEXT OF THE DEVELOPMENT OF EUROPEAN ORIENTALISM IN THE 1850s AND 1860s
Authors: Дэн Ш.
Published: November 2023

В статье представлены основные вехи творческой биографии и международной концертной деятельности французского саксофониста Шарля Суалле (1824–1899), прославившегося под псевдонимом Али-Бен-Су-Алле. Артист характеризуется как виртуозный исполнитель, инструментальный мастер, композитор и талантливый маркетолог, тонко чувствующий художественные запросы европейской аудитории. Уловив интерес современников к восточной экзотике, Суалле создал себе имидж музыканта-востоковеда, окутанный флёром мистики и ориентального шарма.

The article outlines the creative biography and international concert activity of the French saxophonist Charles Soualle (1824–1899), who became famous under the name Ali-Ben-Sou-Alle. The artist is characterized as a virtuoso performer, instrumental wizard, composer, and talented marketer who is subtly sensitive to the artistic requests of the European audience. Capturing the interest of his contemporaries in oriental exoticism, Sualle created the image for himself of an orientalist musician, shrouded in a flair of mysticism and oriental charm.
Mineralized fracture systems of the Skaergaard intrusion, East Greenland
Authors: Bird Dennis K. , Rogers Ralph D. , Manning Craig E.
Published: November 2023

Extensive fracture systems in the Skaergaard intrusion, including veins, sills and dikes, constitute channels for the flow of magmas and hydrothermal solutions during the subsolidus cooling and deformation of the intrusion. The abundance, orientation, transgressive relations and mineralogy of these fracture systems provides a record of fluid transport and chemical reactions during the Skaergaard's subsolidus cooling history.

The earliest mineralized fractures in the Layered Series are gabbroic pegmatites that occur as veins, sills and irregular patches. These structures are crosscut by leucocratic granophyres. Veins filled with hydrothermal minerals occur throughout the Skaergaard intrusion and its host rocks. Hydrothermal minerals in veins are similar to mineral assemblages found in metabasalts ranging in grade from upper amphibolite to zeolite facies. The earliest hydrothermal veins contain upper amphibolite facies assemblages. They are <1-2 mm wide, continuous for tens of metres and occur with frequencies of 0.2 to >1.5 and 1.4 to >20 fractures/metre in the Layered Series, and Marginal Border Group and contact metamorphosed basalts, respectively. These early veins are inferred to have formed at temperatures of >500° to 750°C and <925°to 960°C. Later vein types contain mineral assemblages characteristic of lower amphibolite, greenschist and sub-greenschist facies and occur as more localized fracture systems than the early, high temperature vein types. Compositions of secondary minerals from all of these hydrothermal vein types show systematic changes relative to both the overall fractionation trend and local modal variations in the igneous mineralogy of the Skaergaard intrusion.

­­Observed phase relations and fracture abundances are, in general, consistent with isotopic and transport characteristics of the Skaergaard magma-hydrothermal system reported by Taylor & Forester (1979) and Norton & Taylor (1979).
Brachiopods of the Holm Dal Formation (late Middle Cambrian), central North Greenland
Authors: Zell Mary G. , Rowell Albert J.
Published: November 2023

Brachiopods from the Holm Dai'l Formation are all inarticulates and some 70 percent belong to genera that had an intercontinental Cambrian distribution. The majority of the genera have relatively long stratigraphic ranges; because they are only moderately eurytopic, their chronostratigraphic resolution is modest. The species, however, are more strongly endemic than the genera and consist largely of forms that are known only from North Greenland or are referred to taxa whose distribution is limited to platforms around Cambrian Laurentia; only one species is known from another continent. The fauna consists of 14 species referred to 11 genera of which none of the latter are new. Six of the species are retained in open nomenclature because of limited material or inadequate information. Three of the species are new: Canthylotreta grada, Dactylotreta patriella, and Anabolotreta groenlandica
Thermoluminescence dating and amino acid analyses
Authors: Kronborg C. , Mejdahl V. , Sejrup H. P.
Published: November 2023

No abstract
Topaz, prosopite and closing stages of formation of the Ivigtut cryolite deposit, South Greenland
Authors: Pauly Hans
Published: November 2023

The evolution of the cryolite deposit at Ivigtut is divided into three stages. This work deals with the last two.
Siderite-cryolite (2½ 106 tons) followed by the body of pure, white cryolite accompanied by chiolite (1/2 106 tons) crystallized in Stage 1. An abrupt change in conditions led to Stage 2 in which the fluorite zone and the fluorite-cryolite (1 106 tons) formed. Finally, in Stage 3, fluids left from Stage 2 in fissures and cavities, dissolving cryolite gave rise to thomsenolite and other secondary minerals, (0.08 106 tons).
The cryptocrystalline topaz, emplaced in breccias and vein breccias with fluid izedem placement and penetrating cryolite along, unusual, cleavage planes, indicates that the transition from Stage 1 to Stage 2 was marked by extensive gas-driven explosions related to a Ca-F-rich residue. During these events colloform fluorite precipitated and formed with topaz the fluorite zone in the deeper part of the deposit; above, mechanically admixed cryolite gave rise to the fluorite-cryolite.
Concentrations of the minor elements Mg, K and Sr-Ba resulted in formation of web erite, spherulitic K-mica, jarlite and other Sr-Ba minerals in the last part of Stage 2. Chiolite broke down but cryolite remained stable during most of Stage 2.
Fluids left after Stage 2 dissolved cryolite and thomsenolite, ralstonite and other secondary Ca-fluorides formed. In an early phase of Stage 3 limited explosions precipitated prosopite in fluidized emplaced vein breccias similar to those carrying topaz. These events also led to the formation of the peculiar stalactitic or agate-like fluorite where the explosions hit cavities with solutions rich in Ca.
Appendix: Note on the magnetic polarity time scales used in the Nares Strait volume
Authors: Dawes Peter R.
Published: November 2023

Not available.
Prerequisites for the formation of schools of Chinese Buddhism in the Nanbeichao period.
Authors: Orbodoeva Marina Valer'evna
Published: November 2023

The article examines the initial stage of the formation of schools of Chinese Buddhism in the era of Nanbeichao (Northern and Southern kingdoms). Buddhism of the era of the Southern and Northern Kingdoms (386–589) is a little-studied period in the history of Buddhism in China in domestic science. At the same time, this period represents a very important stage in the development of Buddhism in China, characterized by the completion of the adaptation of Buddhism to the political, social, cultural and mental traditions of this country and the formation of Chinese religious and philosophical principles of Buddhism, which began during the reign of the Eastern Jin Dynasty (317–420) and which continued during the period of the division of China into Southern and Northern kingdoms. The division of China began with the capture of the nomadic tribes of the Tobians of the northern part of the Eastern Jin (317–420). By this time, the rule of the Eastern Jin Dynasty was characterized by political chaos, internal strife, economic decline, famine and devastation. The research is based on translations of sources from Chinese, as well as on the works of Russian scientists. As a result of the study, it can be concluded that it was the period of the Northern and Southern Kingdoms that became a kind of prerequisite for the formation of Chinese schools of Buddhism, the appearance of which marked the final formation of Buddhism in China, known as "Chinese Buddhism". Translations of texts into Chinese became the basis for the formation of schools of Buddhism. The translation activity of Buddhist missionaries of the era of the Southern and Northern Kingdoms, despite the political, economic and social difficulties caused by internecine strife, the invasion of nomadic tribes, devastation and famine, steadily continued. The tradition of translation activities of the Eastern Jin was continued in the Southern and Northern kingdoms. During Southern and Northern Kingdom epoch was made a significant contribution to the development of Buddhism in China, preparing the textual ground for the formation of schools of Chinese Buddhism, which began in the subsequent Sui era (581–618) and ended in the Tang era (618–907).
Intracavity frequency-doubled external-cavity surface-emitting blue laser with high conversion efficiency
Authors: Wu Ya-Dong , Zhu Ren-Jiang , Yan Ri , Peng Xue-Fang , Wang Tao , Jiang Li-Dan , Tong Cun-Zhu , Song Yan-Rong , Zhang Peng ,   College of Physics and Electronic Engineering, Chongqing Normal University, Chongqing 401331, China,   Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China,   Faculty of Sciences, Beijing University of Technology, Beijing 100124, China,   National Center for Applied Mathematics in Chongqing, Chongqing Normal University, Chongqing 401331, China
Published: November 2023

Blue laser with high power and high beam quality has many applications such as in laser display, underwater communication and imaging, and non-ferrous metal processing. Optically pumped external-cavity surface-emitting laser combines the advantages of both surface-emitting semiconductor lasers and solid-state disk lasers, and can produce high output power and good beam quality simultaneously. Its high intracavity circulating power is more conducive to intracavity frequency doubling, achieving high-power and high beam quality blue light through fundamental laser in the near-infrared waveband. This paper reports an efficient intracavity frequency doubled 490 nm high power blue light by using a 980 nm fundamental laser in an external-cavity surface-emitting laser. The V-type resonant cavity is formed by the high reflectivity distributed Bragg reflector (DBR) at the bottom of gain chip, a folded flat concave mirror (high reflectivity coated for 980 nm and anti-reflectivity coated for 490 nm), and a flat concave end mirror (high reflectivity coated for 980 nm and 490 nm). By inserting a nonlinear crystal LBO into the cavity at the beam waist formed by the folded mirror and end mirror, and employing a birefringent filter (BRF) to polarize the fundamental laser and narrow the linewidth of the laser, a high power and high beam quality blue laser with high conversion efficiency is obtained. The effects of different factors including the length of nonlinear crystal, the linewidth of fundamental laser, and the compensation of walk off angle on the output power of the blue laser are studied experimentally. The length of the nonlinear crystal is optimized based on the size of the fundamental laser beam waist at the position of the crystal in the resonant cavity. Under the type-I phase matching condition of LBO, over 6 W output power at 491 nm wavelength is obtained when the crystal length is 5 mm and the BRF thickness is 1 mm. The beam quality M2 factor in the x direction and the y direction are both 1.08, and the conversion efficiency of frequency doubling is 63%. The experimental results also show that symmetrically placed nonlinear crystals can compensate for the walk-off angle during frequency doubling to a certain extent, thereby clearly improving the conversion efficiency of the frequency doubled blue laser.
Chromosome-specific maturation of the epigenome in the Drosophila male germline
Authors: Anderson James T , Henikoff Steven , Ahmad Kami
Published: November 2023

Spermatogenesis in the Drosophila male germline proceeds through a unique transcriptional program controlled both by germline-specific transcription factors and by testis-specific versions of core transcriptional machinery. This program includes the activation of genes on the heterochromatic Y chromosome, and reduced transcription from the X chromosome, but how expression from these sex chromosomes is regulated has not been defined. To resolve this, we profiled active chromatin features in the testes from wildtype and meiotic arrest mutants and integrate this with single-cell gene expression data from the Fly Cell Atlas. These data assign the timing of promoter activation for genes with germline-enriched expression throughout spermatogenesis, and general alterations of promoter regulation in germline cells. By profiling both active RNA polymerase II and histone modifications in isolated spermatocytes, we detail widespread patterns associated with regulation of the sex chromosomes. Our results demonstrate that the X chromosome is not enriched for silencing histone modifications, implying that sex chromosome inactivation does not occur in the Drosophila male germline. Instead, a lack of dosage compensation in spermatocytes accounts for the reduced expression from this chromosome. Finally, profiling uncovers dramatic ubiquitinylation of histone H2A and lysine-16 acetylation of histone H4 across the Y chromosome in spermatocytes that may contribute to the activation of this heterochromatic chromosome.
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis
Authors: Yu Hao , Khanshour Anas M. , Ushiki Aki , Otomo Nao , Koike Yoshinao , Einarsdottir Elisabet , Fan Yanhui , Antunes Lilian , Kidane Yared H. , Cornelia Reuel , Sheng Rory , Zhang Yichi , Pei Jimin , Grishin Nick V. , Evers Bret M. , Cheung Jason Pui Yin , Herring John A. , Terao Chikashi , Song You-Qiang , Gurnett Christina A. , Gerdhem Paul , Ikegawa Shiro , Rios Jonathan J. , Ahituv Nadav , Wise Carol A.
Published: November 2023

Adolescent idiopathic scoliosis (AIS) is a common and progressive spinal deformity in children that exhibits striking sexual dimorphism, with girls at more than five-fold greater risk of severe disease compared to boys. Despite its medical impact, the molecular mechanisms that drive AIS are largely unknown. We previously defined a female-specific AIS genetic risk locus in an enhancer near the
PAX1
gene. Here we sought to define the roles of
PAX1
and newly-identified AIS-associated genes in the developmental mechanism of AIS. In a genetic study of 10,519 individuals with AIS and 93,238 unaffected controls, significant association was identified with a variant in
COL11A1
encoding collagen (α1) XI (rs3753841; NM_080629.2_c.4004C>T; p.(Pro1335Leu); P=7.07e
-11
, OR=1.118). Using CRISPR mutagenesis we generated
Pax1
knockout mice (
Pax1
-/-
). In postnatal spines we found that PAX1 and collagen (α1) XI protein both localize within the intervertebral disc (IVD)-vertebral junction region encompassing the growth plate, with less collagen (α1) XI detected in

Pax1
-/-

spines compared to wildtype. By genetic targeting we found that wildtype
Col11a1
expression in costal chondrocytes suppresses expression of
Pax1
and of
Mmp3
, encoding the matrix metalloproteinase 3 enzyme implicated in matrix remodeling. However, this suppression was abrogated in the presence of the AIS-associated
COL11A1
P1335L
mutant. Further, we found that either knockdown of the estrogen receptor gene
Esr2
, or tamoxifen treatment, significantly altered
Col11a1
and
Mmp3
expression in chondrocytes. We propose a new molecular model of AIS pathogenesis wherein genetic variation and estrogen signaling increase disease susceptibility by altering a
Pax1
-
Col11a1
-
Mmp3
signaling axis in spinal chondrocytes.
Travelling waves or sequentially activated discrete modules: mapping the granularity of cortical propagation
Authors: Orsher Yuval , Rom Ariel , Perel Rotem , Lahini Yoav , Blinder Pablo , Shein-Idelson Mark
Published: November 2023

Numerous studies have identified travelling waves in the cortex and suggested they play important roles in brain processing. These waves are most often measured using macroscopic methods that are unable to assess the local spiking activity underlying wave dynamics. Here we investigated the possibility that waves may not be travelling at the single neuron scale. We first show that sequentially activating two discrete brain areas can appear as travelling waves in EEG simulations. We next reproduce these results using an analytical model of two sequentially activated regions. Using this model, we were able to generate wave-like activity with variable directions, velocities, and spatial patterns, and to map the discriminability limits between travelling waves and modular sequential activations. Finally, we investigated the link between field potentials and single neuron excitability using large-scale measurements from turtle cortex ex-vivo. We found that while field potentials exhibit wave-like dynamics, the underlying spiking activity was better described by consecutively activated spatially adjacent groups of neurons. Taken together, this study suggests caution when interpreting phase delay measurements as continuously propagating wavefronts in two different spatial scales. A careful distinction between modular and wave excitability profiles across scales will be critical for understanding the nature of cortical computations.
Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation
Authors: Mainali Rabina , Buechler Nancy , Otero Cristian , Edwards Laken , Key Chia-Chi , Furdui Cristina , Quinn Matthew A
Published: November 2023

One primary metabolic manifestation of inflammation is the diversion of cis-aconitate within the tricarboxylic acid (TCA) cycle to synthesize the immunometabolite itaconate. Itaconate is well established to possess immunomodulatory and metabolic effects within myeloid cells and lymphocytes, however, its effects in other organ systems during sepsis remain less clear. Utilizing Acod1 knockout mice that are deficient in synthesizing itaconate, we aimed to understand the metabolic role of itaconate in the liver and systemically during sepsis. We find itaconate aids in lipid metabolism during sepsis. Specifically, Acod1 KO mice develop a heightened level of hepatic steatosis when induced with polymicrobial sepsis. Proteomics analysis reveals enhanced expression of enzymes involved in fatty acid oxidation in following 4-octyl itaconate (4-OI) treatment in vitro. Downstream analysis reveals itaconate stabilizes the expression of the mitochondrial fatty acid uptake enzyme CPT1a, mediated by its hypoubiquitination. Chemoproteomic analysis revealed itaconate interacts with proteins involved in protein ubiquitination as a potential mechanism underlying its stabilizing effect on CPT1a. From a systemic perspective, we find itaconate deficiency triggers a hypothermic response following endotoxin stimulation, potentially mediated by brown adipose tissue (BAT) dysfunction. Finally, by use of metabolic cage studies, we demonstrate Acod1 KO mice rely more heavily on carbohydrates versus fatty acid sources for systemic fuel utilization in response to endotoxin treatment. Our data reveal a novel metabolic role of itaconate in modulating fatty acid oxidation during polymicrobial sepsis.
The catalytic mechanism of the RNA methyltransferase METTL3
Authors: Corbeski Ivan , Vargas-Rosales Pablo Andrés , Bedi Rajiv Kumar , Deng Jiahua , Coelho Dylan , Braud Emmanuelle , Iannazzo Laura , Li Yaozong , Huang Danzhi , Ethève-Quelquejeu Mélanie , Cui Qiang , Caflisch Amedeo
Published: November 2023

The complex of methyltransferase-like proteins 3 and 14 (METTL3-14) is the major enzyme that deposits N6-methyladenosine (m6A) modifications on messenger RNA (mRNA) in humans. METTL3-14 plays key roles in various biological processes through its methyltransferase (MTase) activity. However, little is known about its substrate recognition and methyl transfer mechanism from its cofactor and methyl donor S-adenosylmethionine (SAM). Here, we study the MTase mechanism of METTL3-14 by a combined experimental and multiscale simulation approach using bisubstrate analogues (BAs), conjugates of a SAM-like moiety connected to the N6-atom of adenosine. Molecular dynamics simulations based on crystal structures of METTL3-14 with BAs suggest that the Y406 side chain of METTL3 is involved in the recruitment of adenosine and release of m6A. A crystal structure with a BA representing the transition state of methyl transfer shows a direct involvement of the METTL3 side chains E481 and K513 in adenosine binding which is supported by mutational analysis. Quantum mechanics/molecular mechanics (QM/MM) free energy calculations indicate that methyl transfer occurs without prior deprotonation of adenosine-N6. Furthermore, the QM/MM calculations provide further support for the role of electrostatic contributions of E481 and K513 to catalysis. The multidisciplinary approach used here sheds light on the (co)substrate binding mechanism, catalytic step, and (co)product release, and suggests that the latter step is rate-limiting for METTL3. The atomistic information on the substrate binding and methyl transfer reaction of METTL3 can be useful for understanding the mechanisms of other RNA MTases and for the design of transition state analogues as their inhibitors.