bluuebunny/crossref_metadata_2025 huggingface dataset:
Hybrid Nanoparticle/DNAzyme Electrochemical Biosensor for the Detection of Divalent Heavy Metal Ions and Cr3+
Authors: Skotadis Evangelos , Aslanidis Evangelos , Tsekenis Georgios , Panagopoulou Chrysi , Rapesi Annita , Tzourmana Georgia , Kennou Stella , Ladas Spyridon , Zeniou Angelos , Tsoukalas Dimitris
Published: September 2023

A hybrid noble nanoparticle/DNAzyme electrochemical biosensor is proposed for the detection of Pb2+, Cd2+, and Cr3+. The sensor takes advantage of a well-studied material that is known for its selective interaction with heavy metal ions (i.e., DNAzymes), which is combined with metallic nanoparticles. The double-helix structure of DNAzymes is known to dissociate into smaller fragments in the presence of specific heavy metal ions; this results in a measurable change in device resistance due to the collapse of conductive inter-nanoparticle DNAzyme bridging. The paper discusses the effect of DNAzyme anchoring groups (i.e., thiol and amino functionalization groups) on device performance and reports on the successful detection of all three target ions in concentrations that are well below their maximum permitted levels in tap water. While the use of DNAzymes for the detection of lead in particular and, to some extent, cadmium has been studied extensively, this is one of the few reports on the successful detection of chromium (III) via a sensor incorporating DNAzymes. The sensor showed great potential for its future integration in autonomous and remote sensing systems due to its low power characteristics, simple and cost-effective fabrication, and easy automation and measurement.
Scale-Hybrid Group Distillation with Knowledge Disentangling for Continual Semantic Segmentation
Authors: Song Zichen , Zhang Xiaoliang , Shi Zhaofeng
Published: September 2023

Continual semantic segmentation (CSS) aims to learn new tasks sequentially and extract object(s) and stuff represented by pixel-level maps of new categories while preserving the original segmentation capabilities even when the old class data is absent. Current CSS methods typically preserve the capacities of segmenting old classes via knowledge distillation, which encounters the limitations of insufficient utilization of the semantic knowledge, i.e., only distilling the last layer of the feature encoder, and the semantic shift of background caused by directly distilling the entire feature map of the decoder. In this paper, we propose a novel CCS method based on scale-hybrid distillation and knowledge disentangling to address these limitations. Firstly, we propose a scale-hybrid group semantic distillation (SGD) method for encoding, which transfers the multi-scale knowledge from the old model’s feature encoder with group pooling refinement to improve the stability of new models. Then, the knowledge disentangling distillation (KDD) method for decoding is proposed to distillate feature maps with the guidance of the old class regions and reduce incorrect guides from old models towards better plasticity. Extensive experiments are conducted on the Pascal VOC and ADE20K datasets. Competitive performance compared with other state-of-the-art methods demonstrates the effectiveness of our proposed method.
RETRACTED: Mladenov et al. Policy Framework Enabling Flexibility Markets—Bulgarian Case. Technologies 2022, 10, 126
Authors: Mladenov Valeri , Chobanov Vesselin , Ivanova Verzhinia
Published: September 2023

The journal retracts the article “Policy Framework Enabling Flexibility Markets—Bulgarian Case” by Mladenov et al [...]
Metal Ions Modify In Vitro DNA Damage Yields with High-LET Radiation
Authors: Buglewicz Dylan J. , Su Cathy , Banks Austin B. , Stenger-Smith Jazmine , Elmegerhi Suad , Hirakawa Hirokazu , Fujimori Akira , Kato Takamitsu A.
Published: September 2023

Cu2+ and Co2+ are metals known to increase DNA damage in the presence of hydrogen peroxide through a Fenton-type reaction. We hypothesized that these metals could increase DNA damage following irradiations of increasing LET values as hydrogen peroxide is a product of the radiolysis of water. The reaction mixtures contain either double- or single-stranded DNA in solution with Cu2+ or Co2+ and were irradiated either with X-ray, carbon-ion or iron-ion beams, or they were treated with hydrogen peroxide or bleomycin at increasing radiation dosages or chemical concentrations. DNA damage was then assessed via gel electrophoresis followed with a band intensity analysis. DNA damage was the greatest when DNA in the solution with either metal was treated with only hydrogen peroxide followed by the DNA damage of DNA in the solution with either metal post irradiation of low-LET (X-Ray) or high-LET (carbon-ion and iron-ion), respectively, and demonstrated the least damage after treatment with bleomycin. Cu2+ portrayed greater DNA damage than Co2+ following all experimental conditions. The metals’ effect caused more DNA damage and was observed to be LET-dependent for single-strand break formation but inversely dependent for double-strand break formation. These results suggest that Cu2+ is more efficient than Co2+ at inducing both DNA single-strand and double-strand breaks following all irradiations and chemical treatments.
Analyzing the Costs and Benefits of Utilizing a Mixed-Strategy Approach in Infectious Disease Control under a Voluntary Vaccination Policy
Authors: Kabir K. M. Ariful , Ullah Mohammad Sharif , Tanimoto Jun
Published: September 2023

Infectious diseases pose significant public health risks, necessitating effective control strategies. One such strategy is implementing a voluntary vaccination policy, which grants individuals the autonomy to make their own decisions regarding vaccination. However, exploring different approaches to optimize disease control outcomes is imperative, and involves assessing their associated costs and benefits. This study analyzes the advantages and disadvantages of employing a mixed-strategy approach under a voluntary vaccination policy in infectious disease control. We examine the potential benefits of such an approach by utilizing a vaccination game model that incorporates cost and benefit factors, where lower costs and higher benefits lead to reduced infection rates. Here, we introduce a mixed-strategy framework that combines individual-based risk assessment (IB-RA) and society-based risk assessment (SB-RA) strategies. A novel dynamical equation is proposed that captures the decision-making process of individuals as they choose their strategy based on personal or communal considerations. In addition, we explore the implications of the mixed-strategy approach within the context of social dilemmas. We examine deviations from expected behavior and the concept of social efficiency deficit (SED) by allowing for the evolution of vaccine strategy preferences alongside risk perception. By comprehensively evaluating the financial implications and societal advantages associated with the mixed-strategy approach, decision-makers can allocate resources and implement measures to combat infectious diseases within the framework of a voluntary vaccination policy.
Clinical and Molecular Epidemiology of Hemorrhagic Fever with Renal Syndrome Caused by Orthohantaviruses in Xiangyun County, Dali Prefecture, Yunnan Province, China
Authors: Huang Hao , Fu Meng , Han Peiyu , Yin Hongmin , Yang Zi , Kong Yichen , Wang Bo , Yang Xinglou , Ren Tilian , Zhang Yunzhi
Published: September 2023

Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease transmitted by several rodent species. We obtained clinical data of HFRS patients from the medical records of the People’s Hospital of Xiangyun County in Dali Prefecture from July 2019 to August 2021. We collected epidemiological data of HFRS patients through interviews and investigated host animals using the night clip or night cage method. We systematically performed epidemiological analyses of patients and host animals. The differences in the presence of rodent activity at home (χ2 = 8.75, p = 0.031 < 0.05), of rodent-proof equipment in the food (χ2 = 9.19, p = 0.025 < 0.05), and of rodents or rodent excrement in the workplace (χ2 = 10.35, p = 0.014 < 0.05) were statistically different in the four clinical types, including mild, medium, severe, and critical HFRS-associated diseases. Furthermore, we conducted molecular detection of orthohantavirus in host animals. The total orthohantavirus infection rate of rodents was 2.72% (9/331); the specific infection rate of specific animal species was 6.10% (5/82) for the Apodemus chevrieri, 100% (1/1) for the Rattus nitidus, 3.77% (2/53) for the Rattus norvegicus, and 12.50% (1/8) for the Crocidura dracula. In this study, a total of 21 strains of orthohantavirus were detected in patients and rodents. The 12 orthohantavirus strains from patients showed a closer relationship with Seoul orthohantavirus (SEOOV) L0199, DLR2, and GZRn60 strains; the six orthohantavirus strains from Rattus norvegicus and Apodemus chevrieri were closely related to SEOOV GZRn60 strain. One strain (XYRn163) from Rattus norvegicus and one strain (XYR.nitidus97) from Rattus nitidus were closely related to SEOOV DLR2 strain; the orthohantavirus strain from Crocidura dracula was closely related to the Luxi orthohantavirus (LUXV) LX309 strain. In conclusion, patients with HFRS in Xuangyun County of Dali Prefecture are predominantly affected by SEOOV, with multiple genotypes of orthohantavirus in host animals, and, most importantly, these orthohantavirus strains constantly demonstrated zoonotic risk in humans.
Influenza Vaccine Effectiveness in Preventing Laboratory-Confirmed Influenza Cases and Hospitalizations in Navarre, Spain, 2022–2023
Authors: Martínez-Baz Iván , Fernández-Huerta Miguel , Navascués Ana , Pozo Francisco , Trobajo-Sanmartín Camino , Casado Itziar , Echeverria Aitziber , Ezpeleta Carmen , Castilla Jesús
Published: September 2023

We estimated influenza vaccine effectiveness (IVE) in preventing outpatient and hospitalized cases in the 2022–2023 season. A test-negative design included a representative sample of outpatients and all hospitalized patients with influenza-like illness (ILI) from October 2022 to May 2023 in Navarre, Spain. ILI patients were tested by PCR for influenza virus. Influenza vaccination status was compared between confirmed influenza cases and test-negative controls. Among 3321 ILI patients tested, IVE to prevent influenza cases was 34% (95% confidence interval (CI): 16 to 48) overall, 85% (95%CI: 63 to 94) against influenza B, and 28% (95%CI: 3 to 46) against A(H3N2). Among 558 outpatients, 222 (40%) were confirmed for influenza: 55% A(H3N2), 11% A(H1N1), and 31% B. Overall, IVE to prevent outpatient cases was 48% (95%CI: 8 to 70), 88% (95%CI: 3 to 98) against influenza B, and 50% (95%CI: −4 to 76) against A(H3N2). Of 2763 hospitalized patients, 349 (13%) were positive for influenza: 64% A(H3N2), 17% A(H1N1), and 8% B. IVE to prevent hospitalization was 24% (95%CI: −1 to 42) overall, 82% (95%CI: 49 to 93) against influenza B, and 16% (95%CI: −17 to 40) against A(H3N2). No IVE was observed in preventing influenza A(H1N1). IVE was high to prevent influenza B, moderate against A(H3N2) and null against A(H1N1). A lower proportion of influenza B cases may explain the smaller IVE in hospitalized patients than in outpatients. The null IVE against A(H1N1) was consistent with the observed antigenic drift and supports the new composition of the 2023–2024 influenza vaccine.
CMADS and CFSR Data-Driven SWAT Modeling for Impacts of Climate and Land-Use Change on Runoff
Authors: Du Bailin , Wu Lei , Ruan Bingnan , Xu Liujia , Liu Shuai
Published: September 2023

Climate and land-use change significantly impact hydrological processes and water resources management. However, studies of runoff simulation accuracy and attribution analysis in large-scale basins based on multi-source data and different scenario projections are limited. This study employed the Soil and Water Assessment Tool (SWAT) model in conjunction with spatial interpolation techniques to evaluate the accuracy of Climate Forecast System Reanalysis (CFSR), China Meteorological Assimilation Driven Dataset (CMADS), and observation (OBS) in runoff simulations, and configured various scenarios using the Patch-generating Land-use Simulation (PLUS) model to analyze effects of climate and land-use changes on runoff in the Jing River Basin from 1999 to 2018. Results demonstrated the superior performance of the CMADS+SWAT model compared to than CFSR+SWAT model, as the latter underestimated peak runoff. Changes in precipitation had a stronger impact on runoff than temperature, with increased flow from farmland and strong interception effects from forestland. Integrated climate and land-use changes led to an average annual runoff reduction of 1.24 m3/s (I2), primarily attributed to climate change (1.12 m3/s, I3), with a small contribution from land-use change (0.12 m3/s, I4). CMADS exhibited robust applicability under diverse scenarios, effectively enhancing runoff simulation accuracy. The findings provide invaluable guidance for water resources management in semi-arid regions.
Experience in the use of smart technologies in the hotel industry
Authors:   Graduate School of Management, Russian Economic University G. V. Plekhanov, Moscow, Yakovleva D. M.
Published: September 2023

Smart technologies represent an important competitive advantage for any business. The construction of modern hotel complexes provides for the use of smart technologies that improve the quality of service, safety, and economic efficiency of the hotel business.
Labor tourism or migration
Authors:   Federal State Budgetary Educational Institution of Higher Education Russian University of Economics G. V. Plekhanov, Moscow, Batalov P. B.
Published: September 2023

The article discusses the concept of labor tourism and migration, the relationship of these phenomena and features. In the context of globalization, the movement of labor resources is simplified and the phenomenon of labor and business tourism is emerging.
Smart contract and employment contract: are they compatible?
Authors:   Scientific Advisory Council of the Digital Law Laboratory Ural State Law University named after V.F. Yakovlev, Sverdlovsk region, Yekaterinburg, Serova A.V.
Published: September 2023

Smart contract is one of the most developing digital technologies in the field of civil turnover. The question of the legal nature of smart contracts in civil law is debatable. At the same time, it is already necessary to determine the legal possibility of introducing smart contracts in relation to an employment contract. The article analyzes the positive aspects of a smart contract, the potential of which could be revealed in the field of labor. A number of legal obstacles to the conclusion of an employment contract in the form of a smart contract are identified. It is concluded that relations between digital labor platforms and platform workers could be formed in this form today.
Experience of digital transformation of mro in the agro-industrial complex
Authors:   JSC «Fat Plant», Yekaterinburg, Trufakin D. V. , Bykov D. V. ,   JSC «Fat Plant», Yekaterinburg, Sushko A. E. ,   NPO DIATECH LLC, Moscow
Published: September 2023

The article presents the practical experience of digital transformation of the system of maintenance and repair of technological equipment of oil and fat business plants of Rusagro Group by introducing the factory-wide diagnostic software platform SAFE PLANT, which provides data collection from portable devices and stationary wireless systems, their automated processing and prediction of failures, as well as two-way integration with 1C: MRO for effective asset management and adjustment of repair strategies.
Monitoring of numerical simulation of the process of surface hardening treatment of titanium alloys
Authors: Gadalov V.N. , Filonovich A.V. ,   Southwest State University, Kursk, Gubanov O.M. ,   group of companies PJSC «Novolipetsk Metallurgical Combine, Lipetsk, Shchadnykh S.A. ,   Southwest State University, Kursk
Published: September 2023

The paper presents the results of monitoring numerical simulation of the process of surface hardening of titanium alloys VT20 and OT4 by electric spark alloying, which can be used in the design of technological processes for the manufacture of titanium blades of steam turbines. Visualization of the resulting model, carried out using the MatLab computer program, gives a visual representation of the process under study. A good agreement of experimental and calculated (simulated) data allows you to set the parameters of the technological processes of hardening of turbine blades according to the simulation data.
Attainment of Best Practice Recommendations and Late Complications of Patients with Type 1 and Type 2 Diabetes Mellitus
Authors: Lavalle-González Fernando , Vidrio-Velázquez Maricela , Castañeda-Limones Rutila , Almeda-Valdés Paloma , Toapanta-Yanchapaxi Liz , Ochoa-Guzmán Ana , Chiquete Erwin
Published: September 2023

Background: There is a need for information on the current practices of diabetes management to take some actions and improve the attainment of therapeutic goals. Objective. We aimed to describe the attainment of therapeutic targets and late complications of patients with type 1 (T1D) and type 2 (T2D) diabetes mellitus. Material and Methods. In the fourth wave of the International Diabetes Management Practices Study, 1,966 Mexican patients were analyzed (T1D: n=157, 8%; T2D: n=1809, 92%). The cross-sectional phase regarding metabolic profile, current complications, and management are analyzed. Results. Out of T1D patients, 77.6% received insulin alone, and 27.4% had insulin and oral glucose-lowering drugs (OGLD, mostly metformin). Out of T2D patients, 63% received OGLD exclusively (mostly metformin), 4.3% insulin alone, 30.4% OGLD, and insulin, and 2% were on a diet and exercise exclusively. Only 19.7% T1D and 35.9% T2D patients had HbA1c <7% (p=0.01), and only 5.0% of T1D and 3.9% of T2D met the combined therapeutic target of HbA1c <7% + BP <130/80 mmHg + LDL <100 mg/dl. Late diabetes-related complications occurred in 42.7% of T1D and 52.8% of T2D patients, mostly microvascular disease. Macrovascular complications were more frequent in patients with T2D, as compared with T1D (36.8% vs. 16.4%, p<0.001). The number of late complications increased steadily with disease duration, more pronounced in patients with T2D. Conclusions. This study evidences substantial lags in the attainment of clinical goals of patients with diabetes mellitus. There are noticeable differences in the achievement of current therapeutic targets between patients with T1D and T2D in a sample of the Mexican practice.
Oncoguía de leucemia linfoide aguda 2020
Authors: Espinosa Bautista Karla Adriana , Almanza Huante Emmanuel , Córdova Serrano Rosana Daniela , Demichelis Gómez Roberta , Fernández Sánchez Emmanuel
Published: September 2023

In this Oncoguía, we present the epidemiology of acute lymphoblastic leukemia (ALL), its risks, congenital and environmental factors, the initial diagnostic elements, complementary tests, and classification. We also show the treatment protocols used at Instituto Nacional de Cancerología and the ones published in the international literature.
Characteristics and Distribution of Scholarship Donations From Pharmaceutical Companies to Japanese Healthcare Institutions in 2017: A Cross-sectional Analysis
Authors: Murayama Anju , Kamamoto Sae , Saito Hiroaki , Yamashita Erika , Suzuki Yosuke , Tanimoto Tetsuya , Ozieranski Piotr , Ozaki Akihiko
Published: September 2023

Background: Financial relationships between healthcare institutions and pharmaceutical companies can lead to conflicts of interest (COIs), potentially compromising patients’ care. In Japan, scholarship donations, unique type of payments made to healthcare institutions and their subunits by pharmaceutical industries without restricting their use including non-educational or research purpose, may often have implicit promotional purposes. However, detailed information about these payments remains scarce. Methods: This study employed a cross-sectional design to analyse the extent and distribution of all scholarship donations made by all 73 pharmaceutical companies belonging to the Japan Pharmaceutical Manufacturers Association (JPMA) to healthcare institutions in 2017. Data were obtained from publicly available sources from the companies, and the total number of payments, their distributions across various institutions and specialties were analysed. Results: A total of 27 007 payment contracts amounting to $178 703 721 in scholarship donations were made to 4839 specific departments and laboratories at 251 different institutions by 67 pharmaceutical companies. National universities received 50.8% of total payments. All universities setting medical school in Japan received one or more payments. Domestic pharmaceutical companies contributed to $137 797 302 (77.1%) in total. Clinical medicine departments received 89.6% ($160 113 147) with 6.2% ($11 011 946) and 2.0% ($3 600 456) allocated to basic medicine and social medicine specialties, respectively. Conclusion: This study provided a comprehensive overview of scholarship donations from pharmaceutical companies to healthcare institutions in Japan, revealing significant financial support primarily directed to national universities and clinical medicine departments. Japanese policy-makers should consider implementing regulations that promote transparency and mitigate potential COIs arising from scholarship donations, which may be useful in other countries with similar schemes.
Implementation of a Decision Support System for Contract Employee Recruitment Selection using the Simple Multi Attribute Rating Technique (SMART) Method
Authors: Akhif Muhammad
Published: September 2023

LPMP West Sumatra is a company in the technical implementation department of the Ministry of Education and is led by leadership and is responsible to the Director General for Improving the Quality of Educators and Education Personnel (PMPTK). The selection process for hiring contract employees has difficulties because the system is still manual where all the processes from the initial stage of registration selection to the final stage of registration selection are all done manually so it takes quite a long time and is troublesome and drains a lot of energy and energy for the company management. . So there is a need for an online selection information system for contract employee recruitment at LPMP West Sumatra such as a decision support system. This Decision Support System (DSS) uses the Simple Multi Attribute Rating Technique (SMART) method. The SMART method is a decision-making method for handling multi-criteria problems based on calculating the criteria weights for each alternative. The aim of this decision support system was to be able to assist the selection process for hiring contract employees at LPMP West Sumatra quickly, precisely and accurately. The results obtained by the alternative with the name of the prospective contract employee were Ririn Novrianti with a score of 0.755. This helps West Sumatra LPMP leaders in determining prospective contract employees who meet the requirements for employment
The life and work of Moisey Iosifovich Levi and his contribution to preventive disinfection (to his centenary anniversary)
Authors:   Russian Academy of Natural Sciences, Mazin Lev Nikolaevich
Published: September 2023

The biography of the famous domestic disinfectionist, doctor of medical sciences, professor Moisey Iosifovich Levi is given. Keywords: distinguishing features of a scientist, study, work path, scientific developments, contribution to preventive disinfection, improvement of the quality of work of the Moscow desstation to ensure sanitary and epidemiological relief in the city.
RELAÇÃO ENTRE ALEITAMENTO MATERNO EXCLUSIVO E O DESENVOLVIMENTO DE DOENÇAS ALÉRGICAS E INFECCIOSAS
Authors: Figueiredo Silva Macedo Ulysses , Olivandro Duarte Oliveria José , de Sousa Gabriel Igor , Thayne Macêdo Sobreira Pâmela , Barros de Quental Ocilma
Published: September 2023

Objetivo: Identificar a relação entre o aleitamento materno exclusivo e o fortalecimento imunológico. Metodologia: Trata-se de uma revisão integrativa da literatura. As buscas foram realizadas entre os meses de fevereiro e março de 2023, nos bancos de dados nacionais e internacionais, como as plataformas: PUBMED, MEDLINE, LILACS, SciELO, BVS, pré-selecionando produções que se alinhassem com a ideia principal da pesquisa a partir dos descritores cadastrados DECs “Aleitamento materno”; “Sistema imunitário”, “Doenças Infantis”, “Deficiências nutricionais”, “Desmame Precoce”. Foram utilizados estudos disponíveis na íntegra, de forma gratuita, nos idiomas português e inglês, publicados entre os anos de 2018 e 2023. Foram excluídas teses, dissertações e monografias. Resultados e discussões: Os 8 artigos analisados abordam a importância da maturação do sistema imunológico desde o nascimento e a influência significativa da amamentação e dos componentes do leite materno nesse processo. Destaca-se a relevância da microbiota intestinal precoce e dos elementos presentes no leite materno, como anticorpos e citocinas, na proteção contra doenças e infecções. Além disso, ressalta-se a necessidade de promover o aleitamento materno exclusivo até os seis meses de idade como um fator fundamental para o desenvolvimento saudável do sistema imunológico infantil e a prevenção de doenças. Conclusão: Em suma, a intrincada interação entre o desenvolvimento do sistema imunológico infantil, a composição da microbiota intestinal e os benefícios do aleitamento materno torna-se evidente. O sistema imunológico das crianças é moldado desde o momento do nascimento, sendo a microbiota intestinal um componente essencial nesse processo.

Palavras-chave: Aleitamento materno. Deficiências nutricionais. Desmame Precoce. Sistema imunitário.
The Power of Dhikr: Elevating Intellectual, Emotional, and Spiritual Quotients
Authors: Irhas Irhas , Aziz Ahmad Amir , Satriawan Lalu Agus
Published: September 2023

This article aims to solve problems and explain the importance of dhikr in developing intellectual, emotional, and spiritual intelligence. This research focuses on how dhikr can improve cognitive function and reduce stress and anxiety. This research method is a literature study with a psycho-sufism approach. The data were obtained from the results of previous research and also from several journal articles. Data analysis using content analysis. The results of this study indicate that dhikr increases intellectual, emotional, and spiritual intelligence, as seen in increased empathy and emotional regulation. The author explores the spiritual benefits of dhikr, arguing that it can deepen one's relationship with God and provide a sense of purpose and meaning in life. The role of dhikr in holistic development and provides insight into the potential benefits of dhikr practice. The practice of dhikr can profoundly impact a person's intellectual, emotional and spiritual well-being, making it a valuable tool for personal growth and development.
ANALISIS FRAUD DIAMOND DALAM MENDETEKSI FINANCIAL STATEMENT FRAUD (STUDI EMPIRIS PADA PERUSAHAAN MANUFAKTUR SEKTOR INDUSTRI BARANG KONSUMSI YANG TERDAFTAR DI BURSA EFEK INDONESIA (BEI) TAHUN 2017-2019)
Authors: Nabila Nuha  , Sri Ambarwati  , Shanti Lysandra
Published: September 2023

Penelitian ini bertujuan untuk menganalisis pengaruh financial stability, external pressure, nature of industry, change in auditor dan pergantian direksi dalam mendeteksi financial statement fraud. Penelitian ini menggunakan jenis penelitian deskriptif kuantitatif. Sumber data dalam penelitian ini adalah data sekunder berupa data laporan keuangan tahunan perusahaan manufaktur sektor industri barang konsumsi yang terdaftar di Bursa Efek Indonesia (BEI) selama periode 2017-2019. Pemilihan sampel pada penelitian ini dengan menggunakan purposive sampling. Berdasarkan kriteria yang telah ditentukan diperoleh sampel sebanyak 25 perusahaan sehingga data observasi berjumlah 75. Uji hipotesis yang digunakan adalah analisis regresi model panel menggunakan program Eviews 9.0. Hasil penelitian ini menunjukan bahwa financial stability berpengaruh positif signifikan terhadap financial statement fraud. Sedangkan external pressure, nature of industry, change in auditor dan pergantian direksi tidak berpengaruh terhadap financial statement fraud.
PENGARUH CORPORATE SOCIAL RESPONSIBILITY, KOMITE AUDIT, LEVERAGE, DAN RETURN OF ASSET TERHADAP TAX AVOIDANCE.
Authors: Imada Darel Natanael Darel , Yetty Murni  , Widyaningsih Azizah
Published: September 2023

Berdasarkan laporan hasil survei penyidik IMF, Ernesto Crivelly tahun 2016, Indonesia masuk peringkat 11 terbesar dengan nilai diperkirakan 6,48 miliar dolar AS. Penelitian ini bertujuan untuk menganalisis pengaruh corporate social responsibility, komite audit, leverage, dan return on asset terhadap tax avoidance. Penelitian ini mengambil sampel perusahaan LQ45 2018-2019 dari BEI. Berdasarkan kriteria yang telah ditentukan diperoleh sampel sebanyak 28 perusahaan terpilih. Metode analisis dalam penelitian ini menggunakan analisis statistik deskriptif, uji asumsi klasik, uji hipotesis, uji regresi linier berganda, dan uji pemilihan model. Alat untuk penelitian ini menggunakan Eviews9. Hasil penelitian ini menunjukkan bahwa corporate social responsibility dan komite audit tidak berpengaruh terhadap tax avoidance, sedangkan leverage dan return on asset berpengaruh terhadap tax avoidance.
PENGARUH CORPORATE SOCIAL RESPONSIBILITY, INTELLECTUAL CAPITAL DAN STRUKTUR MODAL TERHADAP NILAI PERUSAHAAN
Authors: Indarti Retno , Nelyumna  , Eka Sudarmaji
Published: September 2023

ABSTRAK

Penelitian ini bertujuan untuk membuktikan pengaruh corporate social responsibility, intellectual capital dan struktur modal terhadap nilai perusahaan. Penelitian ini termasuk dalam kategori penelitian deskriptif kuantitatif menggunakan data sekunder. Sampel yang digunakan pada penelitian ini adalah perusahaan perbankan yang terdaftar di Bursa Efek Indonesia periode 2017–2019. Pemilihan sampel dalam penelitian ini yaitu dengan menggunakan purposive sampling. Berdasarkan kriteria sampel yang telah ditetapkan, maka sampel yang dipilih adalah 16 perusahaan dengan total 46 data observasi. Model analisis data menggunakan analisis regresi linier berganda dengan menggunakan software SPSS 22.0 dengan melakukan beberapa tahap pengujian. Hasil penelitian ini menunjukkan bahwa corporate social responsibility dan intellectual capital berpengaruh signifikan terhadap nilai perusahaan, sedangkanb struktur modal tidak berpengaruh signifikan terhadap nilai perusahaan.

Kata Kunci : Corporate Social Responsibility, Intellectual Capital, Struktur Modal, Nilai Perusahaan.
ANALISIS KINERJA KEUANGAN SEBELUM DAN SESUDAH PANDEMI COVID-19 PADA PT. MEDIA NUSANTARA CITRA, Tbk PERIODE 2018-2021
Authors: Raden Roro Fara Diba  , Sudarmaji Eka , Yatim M. Rubiul
Published: September 2023

This study aimed to determine the differences in financial performance before and after the COVID-19 pandemic at PT. Media Nusantara Tbk for the 2018-2021 period. This study used quantitative research with financial ratios: Current Ratio, Debt to Equity Ratio, Return on Asset, Debt to Total Asset Ratio, and Total Asset Turnover. The data analysis method used was paired sample t-test. This study found that the current ratio after the Covid-19 pandemic is higher, with a larger average than before the Covid-19 pandemic. On the other hand, the Return on Assets before the Covid-19 pandemic was higher with a larger average than after the Covid-19 pandemic Total Asset Turnover was higher before the Covid-19 pandemic with a smaller average than after the Covid-19 pandemic. Moreover, the Debt to Equity was higher before the pandemic, and the Debt to Total Asset Ratio was higher with a smaller average than during the pandemic. In conclusion, there was no significant difference between the Current Ratio, Return on Asset, and Total Asset Turnover. However, there was a significant difference between the Debt to Total Asset Ratio and the Debt-to-Equity Ratio.
PENGARUH LIKUIDITAS, LEVERAGE DAN PROFITABILITAS TERHADAP HARGA SAHAM PADA PERUSAHAAN SUBSEKTOR FARMASI YANG TERDAFTAR DI BURSA EFEK INDONESIA (BEI) PADA PERIODE TAHUN 2016-2021
Authors: Nisa Chaerani Nisa , Florida Ariani  , Dini Nuraini
Published: September 2023

Penelitian ini bertujuan untuk mengetahui dan menjelaskan bagaimana pengaruh Current ratio (CR), Debt to Equity Ratio (DER) dan Return on Equity (ROE) terhadap harga saham pada perusahaan subsektor farmasi yang terdaftar di Bursa Efek Indonesia (BEI). Obyek penelitian ini adalah perusahaan subsektor farmasi yang tedaftar di Bursa Efek Indonesia (BEI) periode tahun 2016-2021 dengan jumlah sampel sebanyak 9 perusahaan. Penelitian ini menggunakan teknik purposive sampling. Data yang digunakan data sekunder. Teknik analisis data menggunakan analisis statistik deskriptif dan analisis regresi linier berganda dengan olah data menggunakan Eviews9. Hasil uji hipotesis membuktikan bahwa secara bersama Current ratio (CR), Debt to Equity Ratio (DER) dan Return on Equity (ROE) memiliki pengaruh terhadap harga saham perusahaan subsektor farmasi yang terdaftar di BEI periode tahun 2016-2021. Variabel Current ratio (CR) memiliki pengaruh negatif terhadap harga saham perusahaan subsektor farmasi. Debt to Equity Ratio (DER) memiliki pengaruh negatif terhadap harga saham perusahaan subsektor farmasi. Return on Equity (ROE) tidak memiliki pengaruh terhadap harga saham perusahaan subsektor farmasi.
Adherence to HIV Treatment among Children and Adolescents in Selected Nigerian States: Gaps and Lessons
Authors: Nwokocha Ezebunwa E. , Omoregie Godpower , Dadi Aisha , Nwokocha Lilian I. , Idogho Omokhudu , Anyanti Jennifer
Published: September 2023

By the tenderness of their ages, the responsibility for adhering to HIV-treatment among children and adolescents falls squarely on the shoulders of parents and/or caregivers. Some of the young people that largely follow treatment regimen do so by persuasion and not the strength of their conviction about the essence of the therapy. This study was an appraisal of HIV-treatment adherence among children and adolescents in Anambra, Oyo, Rivers and Taraba states. Data were collected through in-depth and key informant interviews involving critical stakeholders. Findings show that poverty is a major factor in lack of adherence including in the inability to pick up drug due to cost of transportation to facilities; some who experienced viral suppression assumed they had become non-reactive and stopped taking drugs only to relapse; attitude of patients that sometimes suggests that skipping of drugs may not be harmful; lack of food and refusal of patients to take their drugs; adherence fatigue and getting to facilities from distant places including rural areas requiring payment for transportation in the context of poverty; forgetfulness and non-use of alarm clocks for reminders, stigma that prompts some to leave facilities on sighting a familiar person among others. There is need for more vigorous sensitization of communities and caregiver on the essence of strict adherence to treatment as the surest way of attaining viral suppression among young people living with HIV/AIDS.
The Effect of COVID-19 Pandemic on Students’ Motivation towards Secondary School Education in Sokoto State, Nigeria
Authors: Dansabo Muhammad Tasiu , Abdullahi Fatima Idris , Mohammed Ismaila
Published: September 2023

The paper assessed the effect of COVID-19 on education, specifically looking at the pandemic and the education dynamics in Government Secondary School (GSS) Dundaye, Sokoto State, Nigeria. The study employed a mixed-method research design. A sample of 258 respondents (students) was drawn for the quantitative method. A probability sampling technique using a simple random technique was employed to sample students, while 12 participants (teachers) were interviewed to gather qualitative data and such teachers were sampled using a purposive sampling technique. Questionnaires and interview guides were used in generating data for the study. Descriptive statistics were used to analyze the quantitative data, and content analysis was used to generate, analyze, and integrate the important themes from the qualitative data. The COVID-19 epidemic had no beneficial effects on GSS Dundaye’s educational system, rather, the negative effects were visibly seen as reflected in students’ academic performance and dropout of formal schooling, and some students had to abandon schooling for marriage. Some students were eager to marry due to fear of being kidnapped. The study recommended that students who got married but had yet to complete secondary education should be recalled and allowed to finish schooling. This can be achieved by liaising with the husband and parents especially counseling them on the importance of education to the girl-child. The study further recommended that female students should be adequately sensitized to the proactive measures the government is taking to ensure students’ safety in all schools.
How to regenerate the ordinary public spaces after Covid-19 crisis? Recommendations for planners and urban designers
Authors: Paris Mario , Caricati Irene , Vettore Davide
Published: September 2023

The paper discusses the current practices in the regeneration of public spaces starting from research that compares case studies from Milan (I) and Copenhagen (DK) developed by the authors, trying to exceed the rhetoric of the 15-min city, that nowadays is mainstream.

The aim of the paper is to identify potential approaches for designers and planners when they intervene in daily, public spaces that have lost their meaning and identities. Testing existing proposals, the study explores a set of issues that affect the physical, social, and economic condition of places and that should be considered in the process of re-activation.

Discussing the results, the study proposes a set of tools and recommendations that can support the work of urban designers and could foster the social and physical impacts of their work. The conclusions open a perspective on the role of this type of intervention in the construction of the future city.
Factores de riesgo asociados a hemorragia intraventricular en recién nacidos pretérmino
Authors: López López Evi Antoneth
Published: September 2023

PROBLEMA: La hemorragia intraventricular en recién nacidos prematuros sigue siendo un problema clínico importante y un desafío en las unidades de cuidados intensivos neonatales, debido a que alrededor del 50% de los recién nacidos vivos pretérmino lo presentan, lo que conlleva a una alta morbilidad y mortalidad. OBJETIVO: Determinar los principales factores de riesgo asociados a hemorragia intraventricular en recién nacidos pretérmino. MÉTODO: Se llevó a cabo una revisión bibliográfica para identificar los factores de riesgo asociados a hemorragia intraventricular en recién nacidos pretérmino, buscando en la literatura existente en UpToDate, Elsevier, PubMed, utilizando los términos hemorragia intraventricular en recién nacidos pretérmino. RESULTADOS: La edad gestacional al nacer con mayor riesgo de presentar hemorragia intraventricular en promedio es de 32 semanas de gestación y la incidencia global media es del 25%, las peores lesiones han disminuido significativamente a lo largo de los años debido a una mejor comprensión de la fisiopatología y otras consecuencias asociadas. CONCLUSIÓN: Los principales factores de riesgo asociados a hemorragia intraventricular son la edad gestacional, el peso al nacer, infecciones durante el embarazo, sexo y vía de parto.
PROSPECTS FOR THE USE OF ELECTRIC BUSES IN UKRAINE
Authors: Захарчук В.І  , Захарчук О.В,  , Швабюк В.В.
Published: September 2023

The article considers the feasibility of using electric buses in Ukraine. As a result of the literature analysis, it was found that electric transport has a number of advantages over traditional cars. This type of transport in medium-sized cities can be represented by trolleybuses and electric buses. When using trolleybuses, significant capital investments are required for the construction of electrical lines and substations. The main advantages of electric buses are low operating costs, reduction of general background noise in the city, increased comfort for passengers due to low noise and vibrations in the cabin, and the absence of harmful emissions.  Performed technical and operational analysis based on planning data for the main types of urban public transport. A method for assessing the economic efficiency of using electric vehicles has been developed. The economic feasibility of using electric buses in medium-sized cities where public transport is represented by buses and trolleybuses is considered. The research methods are theoretical. The savings in operating costs from replacing a bus with an electric bus of similar passenger capacity are UAH 1 million 600 thousand per year, and from replacing a trolleybus – UAH 1 million 250 thousand UAH per year. As of the beginning of 2022, the cost of running 1 km of an electric bus is UAH 7.2, a trolleybus is UAH 18.8, and a bus is UAH 22. The disadvantage of electric buses, which hinders their wider distribution, is the high cost of batteries, which can be up to 50% of the total cost, as well as lower passenger capacity compared to other modes of transport. A way out of the situation can be the installation of cheaper batteries of smaller capacity on electric buses and the use of recharging at the final stops.
ання підзарядки на кінцевих зупинках.
СИСТЕМА РЕЄСТРАЦІЇ БІОПОТЕНЦІАЛІВ ДЛЯ ЕЛЕКТРОЕНЦЕФАЛОГРАФІЧНИХ ДОСЛІДЖЕНЬ
Authors: Дозорський В.Г.  , Дозорська О.Ф.  , Гевко О.В.  , Дедів Л.Є.
Published: September 2023

В статті проведено обґрунтування структури системи реєстрації біопотенціалів для електроенцефалографічних досліджень. Проведено аналіз типових конструкцій подібних систем, які є присутні на ринку медичної техніки та встановлено, що їм притаманні значні недоліки, пов'язані із недосконалістю електродів для реєстрації електроенцефалографічних сигналів, недосконалістю конструкцій шоломів для фіксації електродів і складністю точного їхнього позиціонування на поверхні голови пацієнтів, схемотехнічних рішень виконання блоків реєстрації біопотенціалів тощо. Запропоновано конструкцію системи реєстрації біопотенціалів, яка може бути виготовлена з допомогою технологій 3D друку, та являє собою монолітну структуру що має крабоподібну форму із центральною та поперечними пластинами, на яких розміщуються підпружинені електроди із спеціальною формою чутливої поверхні. При цьому власне електроди є активними, не потребують додаткового змочування чи застосування контактних гелів. Запропонована структура блока реєстрації біопотенціалів розміщується в потиличній частині конструкції пропонованої системи реєстрації біопотенціалів. Вона являє собою сукупність окремих каналів підсилення та фільтрації біопотенціалів на інструментальних підсилювачах, аналоговий мультиплексор, аналого-цифровий перетворювач та модуль інтерфейсу для передачі даних по каналу BlueTooth на персональний комп’ютер лікаря.
ПРИЙНЯТТЯ РІШЕНЬ ПРИ ЗАБЕЗПЕЧЕННІ ЯКОСТІ ВИПРОБУВАНЬ
Authors: Коробко А.І.  , Котова Ю.М.
Published: September 2023

В статті запропоновано новий спосіб оцінювання співпадіння результатів вимірювань під час виконання процедури забезпечення якості випробувань у лабораторії. Правило прийняття рішення засновано на основі невизначеності вимірювання. В якості кількісного показника запропоновано ймовірність з якою математичні очікування виміряних даних знаходяться у межах невизначеності вимірювання показника. Таким кількісним показником впливу методичної похибки запропоновано відношення різниці між математичними очікуваннями результатів вимірювань отриманих в різних серіях вимірювань до середньої невизначеності їх визначення з урахуванням застосованого правила прийняття рішення. Указаний показник засновано на припущенні того, що результати вимірювань розподілені нормально. Для спрощення процесу розрахунку показників забезпечення якості та зменшення ризиків допущення помилок у розрахунках на базі віртуальної випробувальної лабораторії створено модуль «Coincidence». Вхідними даними для розрахунку співпадіння у модулі є: засоби вимірювальної техніки, безпосередньо результати вимірювань (не менше трьох у кожного випробувача, коефіцієнт охоплення, прізвище осіб, що здійснюють вимірювання та коефіцієнт правила прийняття рішення.
«РОЗУМНИЙ ОДЯГ» ДЛЯ ВІДДАЛЕНОГО МОНІТОРИНГУ СТАНУ СЕРЦЕВО-СУДИННОЇ СИСТЕМИ
Authors: Паляниця Ю.Б.  , Гевко О.В.
Published: September 2023

В статті проведено ґрунтовний аналіз сучасного стану проблеми використання «розумного одягу», обґрунтована важливість моніторингу серцево-судинної системи і доведена доцільність одночасного моніторингу електрокардіографічного та фонокардіографічного сигналів (ФКГ і ЕКГ) з метою інтеграції у текстиль. В роботі проаналізовані типові конструкції подібних систем з врахуванням їх переваг та недоліків. На основі проведеного аналізу наукових праць, розроблено структурний комплекс реєстрації фонокардіографічного та кардіографічного сигналів у однорідних умовах, який умовно можна поділити на три частини: компактний електронний блок з вбудованими в одяг сенсорами, “хмарний” сервіс та комп’ютеризоване робоче місце лікаря. Використовуючи створену структурну схему компактного електронного блоку з вбудованими в одяг сенсорами, запропоновано конструкцію системи, яка здатна інтегруватися у одяг та одночасно проводити моніторинг як фонокардіографічного, так і кардіографічного сигналів з метою глибокого фазового аналізу серцевої діяльності, з акцентом на визначення типу реакції серцево-судинної системи на навантаження, на яку отримано патент України. Показано перспективу даного моніторингу у спортсменів. На основі проведеного теоретичного дослідження та застосування синфазного методу опрацювання синхронно зареєстрованих фонокардіографічного та кардіографічного сигналів отримано спектральні компоненти у термінах енергетичної теорії стохастичних сигналів Драгана Я.П., що є інформотивно-інваріантними ознаками стану серцево-судинної системи яко імерджентно-енергетично-вібраційної з гетеротропним медіа.
АНАЛІЗ СИСТЕМИ КЕРУВАННЯ НА БАЗІ СИСТЕМИ ПРОГРАМУВАННЯ NODE-RED ДЛЯ КОНТРОЛЕРІВ RASPBERRY PI
Authors: Смолянкін О.О.  , Маркіна Л.М.  , Решетило О.М.  , Сацик В.О.
Published: September 2023

В статі проводиться аналіз систем курування в’язкості зернового сусла. Визначена ділянка технологічного процесу, яка на даний момент є малодосліджена з точки зору розробки системи керування, що забезпечить дотримання кількісних та  якісних показників вихідної продукції – спирту, тому вирішення даної проблеми пропонуємо реалізувати з використанням сучасних технологій, а саме із застосуванням середовища візуального програмування Node-Red для керування досліджуваного параметру на основі однопалатного контролера Raspberry Pi. Розроблена система керування в’язкості пшеничного сусла при використанні спирту на базі Node-red може бути ефективним та простим способом для автоматизації процесу виробництва спирту, що дозволяє точно та стабільно контролювати в'язкість сусла та забезпечує високу якість виробу. Наведено приклад програми в середовищі Node-Red з використанням мови JS.