bluuebunny/crossref_metadata_2025 huggingface dataset:
Mapping a single-molecule folding process onto a topological space
Authors: Heidari Maziar , Satarifard Vahid , Mashaghi Alireza
Published: August 2019

Circuit topology provides information on the arrangement of contacts within a folded linear molecular chain. Here, the folding pathways of a restrained (RC) and a free (FCC) chain are mapped onto the topological landscape.
Relevance of Dzyaloshinskii–Moriya spectral broadenings in promoting spin decoherence: a comparative pulsed-EPR study of two structurally related iron(iii) and chromium(iii) spin-triangle molecular qubits
Authors: Robert Jérôme , Parizel Nathalie , Turek Philippe , Boudalis Athanassios K.
Published: August 2019

Two related iron(iii) and chromium(iii) spin-triangle molecular qubits show coherent driving of their spins, and decoherence that is not significantly affected by Dzyaloshikskii–Moriya spectral broadenings.
Impact of water on the BrO + HO2gas-phase reaction: mechanism, kinetics and products
Authors: Tsona Narcisse T. , Tang Shanshan , Du Lin
Published: August 2019

The role of water in preventing the barrierless hydrogen abstraction in the BrO + HO2reaction is highlighted.
Binding energies of the drugs capreomycin and streptomycin in complex with tuberculosis bacterial ribosome subunits
Authors: Vianna Jessica F. , S. Bezerra Katyanna , I. N. Oliveira Jonas , Albuquerque Eudenilson L. , Fulco Umberto L.
Published: August 2019

We calculated the interaction binding energies of the drugs capreomycin and streptomycin in complex with the tuberculosis bacterial ribosome subunits.
CO2 reutilization for methane production via a catalytic process promoted by hydrides
Authors: Grasso María L. , Puszkiel Julián , Fernández Albanesi Luisa , Dornheim Martin , Pistidda Claudio , Gennari Fabiana C.
Published: August 2019

CO2 is recycled to produce CH4 selectively by using complex hydrides as the hydrogen source and catalytic metal particles.
Tetra- and dinuclear manganese complexes of xanthene-bridged O,N,O-Schiff bases with 3-hydroxypropyl or 2-hydroxybenzyl groups: ligand substitution at a triply bridging site
Authors: Ogawa Rina , Suzuki Takayoshi , Hirotsu Masakazu , Nishi Noriyuki , Shimizu Yuu , Sunatsuki Yukinari , Teki Yoshio , Kinoshita Isamu
Published: August 2019

A μ3-alkoxo-bridged tetramanganese(ii,ii,iii,iii) complex was converted to a μ3-oxo-bridged tetramanganese(iii,iii,iii,iii) complex in the presence of a proton source.
Construction of molecularly imprinted nanoplatforms with persistent luminescence for the in vitro specific adsorption and in vivo targeted regulation of food-borne biotoxins
Authors: Liu Jing-Min , Wang Zhi-Hao , Li Chun-Yang , Lv Shi-Wen , Zhao Ning , Wang Shuo
Published: August 2019

Molecularly imprinted nanoplatforms with super-long afterglow persistent luminescence showed in vitro specific adsorption and in vivo targeted regulation ability of food-borne biotoxins by autofluorescence-free nanoimaging.
Cyclodipeptide synthases: a promising biotechnological tool for the synthesis of diverse 2,5-diketopiperazines
Authors: Canu Nicolas , Moutiez Mireille , Belin Pascal , Gondry Muriel
Published: August 2019

This review covers recent approaches for the biosynthesis of diverse 2,5-diketopiperazines using enzymes from cyclodipeptide synthase-dependent pathways.
Raman spectroscopy of bottom-up synthesized graphene quantum dots: size and structure dependence
Authors: Dervishi Enkeleda , Ji Zhiqiang , Htoon Han , Sykora Milan , Doorn Stephen K.
Published: August 2019

Dependence of Raman spectra on nanoparticle size was determined for a series of strongly confined graphene quantum dots.
The application of nanotechnology in enhancing immunotherapy for cancer treatment: current effects and perspective
Authors: Li Yongjiang , Ayala-Orozco Ciceron , Rauta Pradipta Ranjan , Krishnan Sunil
Published: August 2019

Cancer immunotherapy is emerging as a promising treatment modality that suppresses and eliminates tumors by re-activating and maintaining the tumor-immune cycle, and further enhancing the body's anti-tumor immune response.
In situ preparation of a CsPbBr3/black phosphorus heterostructure with an optimized interface and photodetector application
Authors: Chen Keqiang , Wang Yingwei , Liu Jiefeng , Kang Jianlong , Ge Yanqi , Huang Weichun , Lin Zhitao , Guo Zhinan , Zhang Yupeng , Zhang Han
Published: August 2019

An in situ process is taken into account for the preparation of CsPbBr3/BP heterostructure, which leads to the enhanced photoluminescence quenching and charge transfer process.
Transition metal-free C–F/C–Cl/C–C cleavage of ClCF2COONa for the synthesis of heterocycles
Authors: Yan Yizhe , Cui Chang , Wang Jianyong , Li Shaoqing , Tang Lin , Liu Yanqi
Published: August 2019

ClCF2COONa was employed as a C1 synthon for 1,3,5-triazines or quinazolinones in up to 96% yields under transition metal-free and external oxidant-free conditions.
Construction of dimetal-containing dithiolene and Schiff base conjugated polymer coating: exploiting metal coordination as a design strategy for improving infrared stealth properties
Authors: Cai Jingwen , Han Jianhua , Ma Guojia , Liu Xing , Wang Jinyan , Jian Xigao
Published: August 2019

Dimetal-containing dithiolene and Schiff base conjugated polymer coatings are constructed and exhibit excellent stealth abilities in the NIR (near-infrared) and MFIR (mid–far-infrared) range.
Flexible control of excited state transition under pressure/temperature: distinct stimuli-responsive behaviours of two ESIPT polymorphs
Authors: Li Aisen , Liu Hao , Song Chongping , Geng Yijia , Xu Shuping , Zhang Hongyu , Zhang Houyu , Cui Haining , Xu Weiqing
Published: August 2019

The conversion between normal emission and ESIPT can be successfully achieved under pressure and temperature.
Correction: Extracellular histones are clinically associated with primary graft dysfunction in human liver transplantation
Authors: Li Xiuhui , Gou Chunyan , Pang Yanhua , Wang Yakun , Liu Yan , Wen Tao
Published: August 2019

Correction for ‘Extracellular histones are clinically associated with primary graft dysfunction in human liver transplantation’ by Xiuhui Li et al., RSC Adv., 2019, 9, 10264–10271.
Hybrid multi‐agent‐based adaptive control scheme for AC microgrids with increased fault‐tolerance needs
Authors: Bintoudi Angelina D. , Zyglakis Lampros , Tsolakis Apostolos C. , Ioannidis Dimosthenis , Hadjidemetriou Lenos , Zacharia Lazaros , Al‐Mutlaq Nisrein , Al‐Hashem Mohammad , Al‐Agtash Salem , Kyriakides Elias , Demoulias Charis , Tzovaras Dimitrios
Published: August 2019

This paper presents a fault‐tolerant secondary and adaptive primary microgrid control scheme using a hybrid multi‐agent system (MAS), capable of operating either in a semi‐centralised or distributed manner. The proposed scheme includes a droop‐based primary level that considers the microgrid energy reserves in production and storage. The secondary level is responsible for: a) the microgrid units' coordination, b) voltage and frequency restoration and c) calculation of the droop/ reversed‐droop coefficients. The suggested architecture is arranged upon a group of dedicated asset agents that collect local measurements, take decisions independently and, collaborate in order to achieve more complex control objectives. Additionally, a supervising agent is added to fulfill secondary level objectives. The hybrid MAS can operate either with or without the supervising agent operational, manifesting fast redistribution of the supervising agent tasks. The proposed hybrid scheme is tested in simulation upon two separate physical microgrids using three scenarios. Additionally, a comparison with conventional control methodologies is performed in order to illustrate further the operation of a hybrid approach. Overall, results show that the proposed control framework exhibits unique characteristics regarding reconfigurability and fault‐tolerance, while power quality and improved load sharing are ensured even in case of critical component failure.
Bifurcation analysis of bistable and oscillatory dynamics in biological networks using the root‐locus method
Authors: Avcu Neslihan , Güzeliş Cüneyt
Published: August 2019

Most of the biological systems including gene regulatory networks can be described well by ordinary differential equation models with rational non‐linearities. These models are derived either based on the reaction kinetics or by curve fitting to experimental data. This study demonstrates the applicability of the root‐locus‐based bifurcation analysis method for studying the complex dynamics of such models. The effectiveness of the bifurcation analysis in determining the exact parameter regions in each of which the system shows a certain dynamical behaviour, such as bistability, oscillation, and asymptotically equilibrium dynamics is shown by considering two mostly studied gene regulatory networks, namely Gardner's genetic toggle switch and p53 gene network possessing two‐phase (mono‐stable/oscillation) dynamics.
Mass discrepancy analysis for a select sample of Type II-Plateau supernovae
Authors: Martinez Laureano , Bersten Melina C.
Published: August 2019

The detailed study of supernovae (SNe) and their progenitors allows a better understanding of the evolution of massive stars and how these end their lives. Despite its importance, the range of physical parameters for the most common type of explosion, the type II supernovae (SNe II), is still unknown. In particular, previous studies of type II-Plateau supernovae (SNe II-P) showed a discrepancy between the progenitor masses inferred from hydrodynamic models and those determined from the analysis of direct detections in archival images. Our goal is to derive physical parameters (progenitor mass, radius, explosion energy and total mass of nickel) through hydrodynamical modelling of light curves and expansion velocity evolution for a select group of six SNe II-P (SN 2004A, SN 2004et, SN 2005cs, SN 2008bk, SN 2012aw, and SN 2012ec) that fulfilled the following three criteria: (1) enough photometric and spectroscopic monitoring is available to allow for a reliable hydrodynamical modelling; (2) a direct progenitor detection has been achieved; and (3) there exists confirmation of the progenitor identification via its disappearance in post-explosion images. We then compare the masses obtained by our hydrodynamic models with those obtained by direct detections of the progenitors to test the existence of such a discrepancy. As opposed to some previous works, we find good agreement between both methods. We obtain a wide range in the physical parameters for our SN sample. We infer presupernova masses between 10 and 23 M⊙, progenitor radii between 400 and 1250 R⊙, explosion energies between 0.2 and 1.4 foe, and 56Ni masses between 0.0015 and 0.085 M⊙. An analysis of possible correlations between different explosion parameters is presented. The clearest relation found is that between the mass and the explosion energy, in the sense that more-massive objects produce higher-energy explosions, in agreement with previous studies. Finally, we also compare our results with previous physical–observed parameter relations widely used in the literature. We find significant differences between both methods, which indicates that caution should be exercised when using these relations.
Numerical Investigation of a Wood-Chip Downdraft Gasifier
Authors: Vulpio Alessandro , Casari Nicola , Morini Mirko , Pinelli Michele , Suman Alessio
Published: August 2019

Biomass gasification is regarded as one of the most promising technology in the renewable energy field. The outcome of such operation, i.e. the synfuel, can be exploited in several ways, for example powering engines and turbines, and is considered more flexible than the biomass itself. For this reason, a careful analysis of the gasification performance is of paramount importance for the optimization of the process. One of the techniques that can be used for such a purpose, is the numerical analysis. CFD is indeed a tool that can be of great help in the design and study of the operation of the gasifier, allowing for an accurate prediction of the operating parameters. In this work, a downdraft gasifier is considered, and the biomass is made of wood chip. The present analysis is devoted to build the numerical model and simulate all the reactions that happen inside an actual gasifier, considering the drying of the wood chip, heating, pyrolysis, and combustion. Good match with experimental results is found, making the numerical model here presented a reliable virtual test bench where investigating the effects of variation in the working parameters.
Flexibilization of Gas Turbine Combined Cycle via Heat Pump: development of control logics via Software-in-the-loop application
Authors: Rossi Iacopo , Reveillere Adrien , Traverso Alberto
Published: August 2019

Flexibilization of Gas Turbine Combined Cycle (GTCC) is a key for plant operations in the present as well as in the near future. The increasing of non-dispatchable sources in the energy production environment causes strong fluctuations in energy price and energy production profiles. The opportunity to enhance flexibility of traditional GTCC is consequenlty welcomed. This work focuses on integration of a Heat Pump in a GTCC devoted to cogenerative purpose with the goal to integrate energy production, assist the power plant in normal operations and enriches the transient capability of the whole compound. This approach can be developed to be retro-fitted to existing power plant. In particular, a software-in-the-loop (SiL) application is here presented to test the developed control logics governing such power plant. The power plant model is developed and runs under Siemens AMESIM environemnt, whilst the control system is developed and integrated in Matlab/Simulink environment. The two systems are intefraced and exchange information with the goal to verify reliability of the control logics before going into the real field..
Dynamic modeling and simulation of a heat pump system for enhancing cycle flexibility
Authors: Watanabe Yutaka , Traverso Alberto
Published: August 2019

This paper presents a dynamic simulation of a heat pump using butane refrigerant for the purpose of integration with a combined cycle power system and thermal energy storage to enhance flexibility. A dynamic model of a heat pump system is developed using the Amesim software and the simulation result in the case of changing the heat source and heat sink conditions is shown to validate the simulation performance.
Surge prevention in gas turbines: an overview over historical solutions and perspectives about the future
Authors: Niccolini Marmont Du Haut Champ Carlo Alberto , Massardo Aristide Fausto , Ferrari Mario Luigi , Silvestri Paolo
Published: August 2019

The aim of the present work is to retrace experimental, analytical and numerical analyses which deal with compressor instability phenomena, such as rotating stall and surge. While the first affects only the machine itself, the second involves the whole energy system. Surge onset is characterized by strong pressure and mass flow rate fluctuations which can even lead to reverse flow through the compressor. Experimental studies on prevention of axial compressor fluid dynamic instabilities, which can be propagated and eventually damage the solid structure, have been carried out by many authors. The first important studies on this topic tried to underline the main aspects of the complex detailed mechanism of surge, by replacing the compression system with an equivalent conceptual lumped parameter model. This is specially meant to capture the unsteady behaviour and the transient response of the compression system itself, particularly its dependence on variations in the volume of discharge downstream and in the settings of the throttle valve at its outlet (which simulates the actual load coupled to the compressor). Greitzer’s model is still regarded as the milestone for new investigations about active control and stabilization of surge and, more generally, about active suppression of aerodynamic instabilities in turbomachinery. During the last years, a lot of simulations and experimental studies about surge have been conducted on multistage centrifugal compressors with different architectures (e.g. equipped with vaneless or vaned diffusers). Moreover, further kinds of analysis try to extend the stable working zone of compressors, identifying stall and surge precursors extractable from information contained in the vibro-acoustical and rotodynamic response of the system.
Robust Design of a Hybrid Energy System
Authors: Giugno Andrea , Mantelli Luca , Cuneo Alessandra , Traverso Alberto
Published: August 2019

Nowadays the research in energy field is focused on conversion technologies which could achieve higher efficiencies and lower environmental impact. Among these, fuel cells are considered an extremely promising technology and pressurized solid oxide fuel cell (SOFC) systems are particularly attractive for their high electric efficiency, potential for cogeneration applications, low carbon emissions and high performance at part-load. This paper aims to perform a robust design of an innovative turbocharged hybrid system model, featuring components validated with industrial data, where a turbocharger is used to pressurize the fuel cell, promising better cost effectiveness than a microturbine-based hybrid system, at small scales. This study will evaluate the impact of the main operating parameters (fuel cell area, stack current density and recuperator surface) on the plant performance, considering uncertainties in the system and creating a response surface of the model to perform the study. Finally, a study of the operating costs of such plant is performed to evaluate its profitability in the Italian market scenario.
Potential energy recovery from LNG regasification in LNG-fueled ships
Authors: Pasini Gianluca , Baccioli Andrea , Ferrari Lorenzo , Desideri Umberto
Published: August 2019

Recent regulatory initiatives regarding ships emissions raised the interest of maritime operators on cleaner fuels. The International Maritime Organization (IMO) with Annex VI of the International Convention for the Prevention of Pollution from Ships (MARPOL) set strict limits on SOx , NOx and CO2 emissions. Many studies have been carried out to increase engine efficiency based on waste heat recovery such as ORC or turbo-compounding. Using LNG as a fuel opens new opportunities in this prospect. In this study, an energy recovery from LNG regasification process, through a dedicated and optimized cycle, is investigated. The system is made of an open supercritical Rankine cycle performed before engine injection and exploiting LNG as a working fluid. Results showed the influence of the maximum temperature and pressure of the cycle on the system performance. A maximum power recovery up to 2.2% of main engine power was found.
Gas turbine prime movers fuelled by LNG as a future alternative for sustainable power in marine propulsion: current emission policy assessment and exhaust quality evaluation
Authors: Barsi Dario , Bono Andrea , Satta Francesca , Zunino Pietro
Published: August 2019

In recent years, climate change has dramatically shown its effects in terms of fluctuations of temperatures because of increased global warming due to greenhouse gas emissions. Pollution control is strongly linked to atmospheric acidification and contaminants in combustion exhausts. In such a contest, marine propulsion is actually a key player that is accounting for a substantial contribution to pollution. Kyoto protocol’s obligations established decarbonisation as a compulsory commitment and contaminant constraints are defined by current emission policy and regulations both on a global and on a regional basis. In this paper, a study is carried out in order to develop a framework for current emission policy and assessment of exhausts due to constraints imposed on fuel choice. Gas fuelled marine propulsion, implemented through state-of-the-art GT areoderivative prime movers, powered by LNG, is analysed from the environmental point of view. The pollutant emissions from various size GT models are evaluated through both GT datasheets and commercial (as well as self-coded) software, in order to assess the validity of LNG as an alternative fuel option for future sustainable marine applications.
Evaluating LCOE in sustainable microgrids for smart city applications
Authors: Bracco Stefano , Delfino Federico , Laiolo Paola , Pagnini Luisa , Piazza Giorgio
Published: August 2019

A microgrid can be considered a profitable solution to be adopted in smart cities if it is marketable, i.e. more, or at least equally convenient than other traditional energy supply sources. Different economic parameters can be defined to determine its affordability. In particular, the LCOE (Levelized Cost of Electricity) is the most popular indicator adopted in the energy sector, widely used both for conventional and renewable power sources. However, the use of this metric still disregards important aspects that concerns microgrid applications. After providing a state-of-the-art of the use of LCOE, the present paper proposes a new methodology for sustainable microgrids in smart city, taking into account benefits due to cogeneration and trigeneration, integration costs as well as positive and negative side effects.
Design of a sustainable polygeneration microgrid for the retrofitting of an industrial site: Ansaldo Energia case study
Authors: Bianchi Enrico , Bracco Stefano , Cannizzaro Fabio , Delfino Federico , Giacchino Alessandro
Published: August 2019

The aim of this paper is that of proposing a methodology on how to design a microgrid for an industrial area. In particular, the paper reports the description of a project, jointly developed by the University of Genoa and Ansaldo Energia SpA, to design a polygeneration microgrid for the industrial site of Ansaldo Energia company in the Metropolitan City of Genoa. The microgrid infrastructure integrates different technologies to satisfy the electrical, thermal and cooling demand of the site, among which an important role is played by the cogeneration AE T100 microturbines developed by the company. In the paper, the optimization tool AEN-MGD, developed to optimally design and operate the microgrid, is described and different possible configurations of the microgrid are investigated and analysed from the technical, economic and environmental point of view. The proposed model has a general validity and it can be used to design and operate other similar energy infrastructures.
Energy Harvesting Technology for turbocompounding automotive engines with waste-gate valve
Authors: Usai Vittorio , Marelli Silvia , Renuke Avinash , Traverso Alberto
Published: August 2019

The reduction of CO2 and, more generally, GHG (Green House Gases) emissions imposed by the European Commission (EC) and the Environmental Protection Agency (EPA) for passenger cars has driven the automotive industry to develop technological solutions to limit exhaust emissions and fuel consumption, without compromising vehicle performance and drivability. In a mid-term scenario, hybrid powertrain and Internal Combustion Engine (ICE) downsizing represent the present trend in vehicle technology to reduce fuel consumption and CO2 emissions. Concerning downsizing concept, to maintain a reasonable power level in small engines, the application of turbocharging is mandatory for both Spark Ignition (SI) and Diesel engines. Following this aspect, the possibility to recover the residual energy of the exhaust gases is becoming more and more attractive, as demonstrated by several studies around the world. One method to recover exhaust gas energy from ICEs is the adoption of turbo-compounding technology to recover sensible energy left in the exhaust gas by-passed through the waste-gate valve. In the paper, an innovative option of advanced boosting system is investigated through a bladeless micro expander, promising attractive cost-competitiveness. The numerical activity was developed on the basis of experimental data measured on a waste-gated turbocharger for downsized SI automotive engines. To this aim, mass flow rate through the by-pass valve and the turbine impeller was measured for different waste-gate settings in steady-state conditions at the turbocharger test bench of the University of Genoa. The paper shows that significant electrical power can be harvested from the waste-gate gases, up to 94 % of compressor power, contributing to fuel consumption reduction.
Numerical identification of the thermal conductivity tensor and the heat capacity per unit volume of an anisotropic material
Authors: Atchonouglo Kossi , Dupré Jean-Christophe , Germaneau Arnaud , Vallée Claude
Published: August 2019

In this paper, an inverse approach based on gradient conjugate method for thermal conductivity tensor and heat capacity per unit volume measurement is summarized. A suitable analysis is done for the mesh in finite element method and for the time steps for the time integration. For a composite material, it is shown the importance to identify the thermal conductivity tensor components in the principal axes.
How should be the laboratory application? Prospective teachers' perspective
Authors: Alkan Fatma
Published: August 2019

The importance and effectiveness of laboratory applications should be find out by students or teachers. The aim of this study is to examine the perceptions on laboratory applications of prospective teachers and to determine the opinions about chemistry laboratory practices. The study group consisted of 1st grade prospective teachers. The research has been designed in a mixed method design. In the quantitative dimension of the study, the data obtained from the perceptions on laboratory applications scale were analysed. In the qualitative dimensions of the study was carried out in accordance with the situation pattern, and focus group interviews were conducted. According to quantitative findings of the research, the highest scores of sub-scales is in the effectiveness of laboratory. In qualitative findings, it has been emphasized that laboratory applications still bring chemistry lessons more enjoyable, provide knowledge retentions with practical applications, develop responsibility, improve the preparation behaviour of the course.
The 2013-2018 interdisciplinary summer workshops around the wooden monument church in Crivina de Sus village, Romania
Authors: Obradovici Vladimir
Published: August 2019

This article describes an ongoing project, starting in 2013, in which interdisciplinary summer workshops were held in Crivina de Sus, Timis County, Romania, attended by specialists and students from different fields. Within these workshops, it was watched as a Cultural Landscape and its components could be viewed and studied from different perspectives of related specialties in order to obtain a comprehensive and complete picture of the context. These specialties have taken account of each other and have learned the methods and points of view specific to each field. Following these workshops, the conclusions of the studies were summed up and used in a project to promote, value and improve the cultural landscape.
STEAM approach in architectural education
Authors: Makaklı Elif Süyük
Published: August 2019

Architecture practice is reshaped by new technological developments such as virtual reality, augmented reality, 3D printing, computational design, robotics, etc. Future architects are expected to deliver spatial solutions, to understand changing living conditions and to discover the different future by responsing technological improvements. In architecture schools, students should explore and investigate design practice with different production methods, systems and materials by using various technologies in collaborations with interdisciplinary partners and industry. The study aims to understand the STEAM concept which is considered as a promising education approach and formulated; science, technology, engineering, math and then adds an ‘A’ for arts which represents the creative thinking and design approach. The STEAM concept and its place in the architectural education are discussed. The discipline of architecture is an intersection of technology, art and science. The architecture schools' curriculum reflects the interdisciplinary STEAM nature throughout the history. Virtual Reality (VR) is created through interdisciplinary technology and has the potential to prepare the students to future, to develop analytical and abstraction abilities.
Humanitarian framework of modern pedagogical education in Russia
Authors: Siraeva Marina
Published: August 2019

The goal of the paper is to review and classify current trends and outcomes of modern pedagogical education in Russia on the back of humanitarization of higher education as well as to justify principles of humanitarization of higher education content. The relevance of this subject stems from current shifts of socio-economic environment in Russia, which have brought new humanitarian paradigms to the forefront. The authors examine pedagogical process as a humanitarian phenomenon pursuing the aim to specify the goals and objectives of modern pedagogical education. The article highlights current demand to develop and promote pedagogical tools of humanitarian training as a model based on cultural practices which consequently implies structuring of the education content and process according to a person’s nature, mind and spirit, contributing to the integrity of a human’s inner world and the development of a whole person.
A Proposal for Global-Change Education based on an educational board game: A Planet on the Abyss
Authors: Pérez-Fernández Beatriz , Vázquez-Vílchez Mercedes , Fernández-Oliveras Alicia
Published: August 2019

“Global change” is a complex term still widely unknown, and often confused with climate change. The Spanish Secondary School Curriculum indicates that the idea of global change is absent. Globalchange components are distributed among different subjects and courses. This scattering of the subject matter hinders students from gaining a cohesive understanding of global change and its implications. The main objective of this proposal is to develop an educational approach aimed at expanding children's knowledge regarding global change, and fomenting awareness of the interrelations between human actions and this environmental crisis. In addition, we seek to aid students in understanding that the adoption of certain practices could help them achieve a sustainable lifestyle. To this end, we have designed and manufactured a prototype board game called “A Planet on the Abyss”, with a cooperative play. The pilot study realized have showed that the students recognize that Global Change incorporates more components than climate change and the students related Global Change with an anthropocentric origin and they became to use new terms, such as habitats, ecosystems, deforestation, etc.
Cyprus in Turkish Poetry İbrahim Zeki Burdurlu and Arif Nihat Asya the Impact of Cyprus
Authors: Karabacak Esra
Published: August 2019

Ibrahim Zeki Burdurlu and Arif Nihat Asya, who worked as teachers in Cyprus, expressed their impressions of Cyprus and shared the problems faced by the Turkish Cypriots. Ibrahim Zeki Burdurlu has a very soft expression. When history and Cyprus come together, the values of a literature teacher extending from Namık Kemal to Gazi Kemal are expressed. Arif Nihat Asya was a teacher in Cyprus and wrote poems similar to that of İbrahim Zeki Burdurlu. Probably the indifference of the measure and the occasional immeasurability, which are among the elements of Burdurlu's poetry, have aroused influence in Turkish Cypriot poetry. In the meantime, although the understanding of populist poetry nurtured the understanding of easy-to-write poetry, it was effective in Burdurlu's poems. In this study, Cyprus, Ibrahim Zeki Burdurlu and Arif Nihat Asya's poems in post-Republic Turkish poetry will be examined comparatively with example poems by completing them especially in terms of using language.

[1–4].
Entzündet oder überaktiv?
Authors: Vigl Sebastian
Published: August 2019

Rezidivierende Zystitis und Reizblase sind häufige Krankheitsbilder, vor allem bei Frauen. Dabei ist eine Zystitis bakteriell verursacht, während die Reizblase durch funktionelle Störungen auftritt. Da sich die Pathogenesen bei Zystitis und Reizblase unterscheiden, muss für die Therapie trotz teilweise ähnlicher Symptome die Ursache geklärt werden. Das erfolgt unter anderem durch urologische Untersuchungen und Urindiagnostik. Kombinierte Arzneipflanzen können als Teerezeptur sowohl bei rezidivierender Zystitis als auch bei einer Reizblase eingesetzt werden. Dabei kann man Teedrogen entsprechend individueller Unterschiede ergänzen.
Idiopathic Pruritus Ani and Acute Perianal Dermatitis
Authors: Ortega Adrián E. , Delgadillo Xavier
Published: August 2019

This article reviews the etiologies, pathophysiology, clinical evaluation, and treatment of idiopathic pruritus ani and perianal dermatitis. It underscores a practical approach to each of these common proctologic conditions.
Convenient Synthesis of 2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)-benzenesulfonyl Chloride, A Key Building Block of Penoxsulam
Authors: Huang Shuai Shuai , Zheng Zhan Jiang , Cui Yu Ming , Xu Zheng , Yang Ke Fang , Xu Li Wen
Published: August 2019

A convenient and efficient three-step synthesis of 2-(2,2-difluoroethoxy)-6-(trifluoromethyl)benzenesulfonyl chloride, the key building block of penoxsulam, is described. The main features of the synthesis include a regioselective lithiation and subsequent electrophilic substitution starting from commercially available 3-bromobenzotrifluoride to provide (2-bromo-6-(trifluoromethyl)phenyl)(propyl)sulfane, then a copper-catalyzed C–O coupling to introduce the difluoroethoxy moiety and chloroxidation conditions to give the desired sulfonyl chloride.
Early Recognition and Diagnosis of Buried Bumper Syndrome: A Report of Three Cases
Authors: Devia Johan , Santivañez Juan Jose , Rodríguez Mario , Rojas Sandra , Cadena Manuel , Vergara Arturo
Published: August 2019

Buried bumper syndrome (BBS) was described as a complication of percutaneous endoscopic gastrostomy (PEG) that occurs when the internal stump of the probe migrates and is located between the gastric wall and the skin. The increase of compression between the internal stump and the external stump of the gastrostomy tube causes pain and the inability to feed. We present the cases of three patients with BBS managed by the metabolic and nutritional support department. These cases intend to illustrate one of the less frequent complications of PEG, clinical presentation, risk factors, diagnosis, and especially clinical management. Although there are no defined gold standards for its management, the most important points in the management of this condition are early recognition, recommendations to avoid ischemic process at the moment of the insertion of the tube, specific care of the gastrostomy tube, and a periodic nutrition evaluation to avoid overweight, which causes traction and excessive pressure in the gastric wall. It is important for physicians to be aware of the recommendations to prevent BBS and its complications, especially in patients in whom communication can be difficult secondary to their pathologies and comorbidities.
Treatment of Closed Tibia Shaft Fractures in Children: A Systematic Review and Meta-Analysis
Authors: Stenroos Antti , Puhakka Jani , Nietosvaara Yrjänä , Kosola Jussi
Published: August 2019

Tibia fractures are among the most common long-bone fractures in children. Despite this, there is no current consensus on the optimal treatment strategy for closed displaced tibia shaft fractures in the pediatric patient population. The aim of this study is to compare the reported complications and outcomes of reduction and cast immobilization versus flexible intramedullary nailing in the treatment of pediatric tibia shaft fractures. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement when conducting and reporting this prospectively registered systematic review. Eleven studies were included. Quality of the studies was assessed using the Coleman methodology score. Mantel–Haenszel cumulative odds ratios were used to compare the risk of complication between different methods of treatment. Eleven studies including 1,083 patients with diaphyseal fractures of the tibia met the inclusion criteria. The most common fracture type was simple 42-A (782; 91%). Majority (75%) of the patients were treated nonoperatively. The total complication rate was higher among operatively treated patients (24 vs. 9%; p < 0.05). Satisfactory fracture alignment had to be restored surgically in 5% of the primarily nonoperatively treated patients. The evidence levels of the included studies were II (1), III (2), and IV (7). Three-fourths of closed diaphyseal fractures of the tibia in children are still treated with reduction and cast immobilization. Flexible intramedullary nailing is associated with significantly higher complication rate than nonoperative treatment.
Antenatal Periviability Counseling and Decision Making: A Retrospective Examination by the Investigating Neonatal Decisions for Extremely Early Deliveries Study Group
Authors: Feltman Dalia M. , Fritz Katie A. , Datta Avisek , Carlos Christine , Hayslett Drew , Tonismae Tiffany , Lawrence Christin , Batton Emily , Coleman Tasha , Jain Meenu , Andrews Bree , Famuyide Mobolaji , Tucker Edmonds Brownsyne , Laventhal Naomi , Leuthner Steven
Published: August 2019

Objective To describe periviability counseling practices and decision making.

Study Design This is a retrospective review of mothers and newborns delivering between 22 and 24 completed weeks from 2011 to 2015 at six U.S. centers. Maternal and fetal/neonatal clinical and maternal sociodemographic data from medical records and geocoded sociodemographic information were collected. Separate analyses examined characteristics surrounding receiving neonatology consultation; planning neonatal resuscitation; and centers' planned resuscitation rates.

Results Neonatology consultations were documented for 40, 63, and 72% of 498 mothers delivering at 22, 23, and 24 weeks, respectively. Consult versus no-consult mothers had longer median admission-to-delivery intervals (58.7 vs. 8.7 h, p < 0.001). Consultations were seen more frequently when parental decision making was evident. In total, 76% of mothers had neonatal resuscitation planned. Resuscitation versus no-resuscitation newborns had higher mean gestational ages (24.0 vs. 22.9 weeks, p < 0.001) and birthweights (618 vs. 469 g, p < 0.001). Planned resuscitation rates differed at higher (HR) versus lower (LR) rate centers at 22 (43 vs. 7%, p < 0.001) and 23 (85 vs. 58%, p < 0.001) weeks. HR versus LR centers' populations had more socioeconomic hardship markers but fewer social work consultations (odds ratio: 0.31; confidence interval: 0.15–0.59, p < 0.001).

Conclusion Areas requiring improvement included delivery/content of neonatology consultations, social work support, consideration of centers' patient populations, and opportunities for shared decisions.
Presentation of Intrahepatic Cholangiocarcinoma with Fulminant Hepatic Failure: A Case Report
Authors: Pratap Thara , Jalal Muhammed Jasim Abdul , Mahadevan Pushpa , Koshy Abraham , Mukkada Roy J. , Mathew Pradeep G. , Sebastian Rithu
Published: August 2019

Fulminant hepatic failure as initial presentation due to diffuse parenchymal infiltration by cholangiocarcinoma is a rare entity. We present the case of a 49-year-old female patient who had a fatal outcome with acute liver failure due to diffuse intrahepatic cholangiocarcinoma. No definite mass lesion was identified on cross-sectional imaging. The final diagnosis was made on transjugular liver biopsy. This discussion highlights the possibility of infiltrative cholangiocarcinoma as a rare cause of fulminant hepatic failure.
Unusual Etiologies for Vascular Duodenal Compression Mimicking the Superior Mesenteric Artery (SMA) Syndrome: The SMA-Like Syndrome
Authors: Dross Peter E. , Molavi Shawdon , Chan Alex , Latshaw Rachael , Chhabra Pankaj
Published: August 2019

We report a series of nine cases of unusual etiologies for vascular duodenal compression that do not meet the diagnostic criteria for superior mesenteric artery (SMA) syndrome and propose that “SMA-like syndrome” be used to classify these vascular duodenal compression cases.
Ossifying Fibroma of Dorsal Spine in a Postpartum Female: A Rare Case Report
Authors: Reddy Musali Siddartha , Rao Gollapudi Prakash , Imran Mohammed , Nookathota Uday Goutam
Published: August 2019

A rare case of monostotic ossifying fibroma of the dorsal spine in a postpartum woman is being described. Ossifying fibromas of the spine are very rare tumors. They are components of benign fibro-osseous lesions. We report a case of an 18-year-old woman, who presented with complaints of weakness of both the lower limbs in the immediate postpartum period and was diagnosed with ossifying fibroma of the dorsal [D3] vertebral body. The tumor was excised followed by spinal stabilization. Histopathologic findings were consistent with ossifying fibroma. Postoperative period was uneventful. Monostotic variant of ossifying fibroma in the dorsal spine is an extremely rare tumor, and its presence in the postpartum period adds on to the diagnostic dilemma. Hence this case report can be kept in mind while evaluating a case presenting with complaints of weakness of both the lower limbs in the immediate postpartum period.
Discovering the topology of complex networks via adaptive estimators
Authors: Burbano Lombana Daniel Alberto , Freeman Randy A. , Lynch Kevin M.
Published: August 2019

Behind any complex system in nature or engineering, there is an intricate network of interconnections that is often unknown. Using a control-theoretical approach, we study the problem of network reconstruction (NR): inferring both the network structure and the coupling weights based on measurements of each node’s activity. We derive two new methods for NR, a low-complexity reduced-order estimator (which projects each node’s dynamics to a one-dimensional space) and a full-order estimator for cases where a reduced-order estimator is not applicable. We prove their convergence to the correct network structure using Lyapunov-like theorems and persistency of excitation. Importantly, these estimators apply to systems with partial state measurements, a broad class of node dynamics and internode coupling functions, and in the case of the reduced-order estimator, node dynamics and internode coupling functions that are not fully known. The effectiveness of the estimators is illustrated using both numerical and experimental results on networks of chaotic oscillators.
Effects of synaptic and myelin plasticity on learning in a network of Kuramoto phase oscillators
Authors: Karimian M. , Dibenedetto D. , Moerel M. , Burwick T. , Westra R. L. , De Weerd P. , Senden M.
Published: August 2019

Models of learning typically focus on synaptic plasticity. However, learning is the result of both synaptic and myelin plasticity. Specifically, synaptic changes often co-occur and interact with myelin changes, leading to complex dynamic interactions between these processes. Here, we investigate the implications of these interactions for the coupling behavior of a system of Kuramoto oscillators. To that end, we construct a fully connected, one-dimensional ring network of phase oscillators whose coupling strength (reflecting synaptic strength) as well as conduction velocity (reflecting myelination) are each regulated by a Hebbian learning rule. We evaluate the behavior of the system in terms of structural (pairwise connection strength and conduction velocity) and functional connectivity (local and global synchronization behavior). We find that adaptive myelination is able to both functionally decouple structurally connected oscillators as well as to functionally couple structurally disconnected oscillators. With regard to the latter, we find that for conditions in which a system limited to synaptic plasticity develops two distinct clusters both structurally and functionally, additional adaptive myelination allows for functional communication across these structural clusters. These results confirm that network states following learning may be different when myelin plasticity is considered in addition to synaptic plasticity, pointing toward the relevance of integrating both factors in computational models of learning.
Bipolar resistive switching with self-rectifying behaviors in p-type AgCr1−xMgxO2 thin films
Authors: Li C. H. , Yang B. B. , Hu W. J. , Wei R. H. , Hu L. , Tang X. W. , Yang J. , Dai J. M. , Zhu X. B. , Sun Y. P.
Published: August 2019

Resistive random access memories with self-rectifying behaviors, in which the sneak-path issue in passive crossbar arrays can be alleviated without additional access devices, have been investigated recently. The applications of p-type transparent oxide semiconductors as a memory medium will pave the way for realizing all-transparent memories and integrating on the complementary metal-oxide-semiconductor devices. Here, Ag-based p-type delafossite AgCr1−xMgxO2 thin films were prepared onto n-Si wafers to investigate the resistive switching (RS) performance. Bipolar RS with self-rectifying behaviors were observed in the Au/AgCr0.92Mg0.08O2/n−Si sandwich structure, showing improved rectification ratio, On/Off ratio, and switching durability. The change of the oxygen vacancy concentration resulting from Mg doping plays a key role in determination of the RS. The intrinsic rectifying behavior in the low resistance state is attributed to the existence of a Schottky-like barrier in the AgCr1−xMgxO2/n−Si p-n heterojunction. The RS behavior originates from the modification of the barrier, which is induced by the trapping/detrapping of charge carriers in oxygen vacancies at the interface. The results will provide novel RS devices based on p-type transparent delafossite thin films with a self-rectifying feature.
Molecular beam epitaxy growth and optical properties of InAsSbBi
Authors: Schaefer S. T. , Kosireddy R. R. , Webster P. T. , Johnson S. R.
Published: August 2019

The molecular beam epitaxy growth and optical properties of the III-V semiconductor alloy InAsSbBi are investigated over a range of growth temperatures and V/III flux ratios. Bulk and quantum well structures grown on the (100) on-axis and offcut GaSb substrates are examined. Bismuth readily incorporates at growth temperatures around 300 °C but results in materials with limited optical quality. Conversely, higher growth temperatures around 400 °C yield improved optical performance but with limited Bi incorporation. Photoluminescence spectroscopy is used to examine the optical properties and bandgap energies of InAsSbBi layers grown at temperatures from 400 to 430 °C using 0.91 and 0.94 As/In flux ratios, 0.10 and 0.12 Sb/In flux ratios, and 0.05 and 0.10 Bi/In flux ratios. Emission is observed from low to room temperature with peaks ranging from 3.7 to 4.6 μm. The relationships between Bi incorporation, surface morphology, growth temperature, and group-V flux are examined. Large concentrations of Bi-rich surface features are observed on samples where the incident Bi flux neither fully incorporates nor desorbs but instead accumulates on the surface and coalesces into droplets.