bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Challenges for Blockchain Adoption in Enterprise Distributed Applications
Authors: Siddiqui Zeeshan Ali , Haroon Mohd.
Published: September 2023

Decentralization, auditability, smart execution, and security are four ways that blockchain technology (BCT) differs from current cutting-edge technologies based on client-server architecture. Without the need of any middlemen, blockchain technology builds trust between untrustworthy parties. By employing its distinctive properties, blockchain technology is presently used to address the problems of enterprise distributed applications (EDAs) to some extent. As a result, businesses involved in a wide range of industries have shown interest in it. Despite being praised as tool for businesses to create secure applications, BCT is still not widely used. The objective of the current study is to use an extension of the technology acceptance model (TAM2), constituted by 15 hypotheses (H1–H15), to address the factors that influence professionals' desire to adopt the BCT in the EDAs. In order to achieve the research objective, the study consists of a quantitative non-experimental correlational method with the goal of creating an empirical model to evaluate the relationship between perceived usefulness, perceived ease of use, scalability, effort, performance, adaptability, maintainability, experience, and blockchain adoption in India with a focus on EDAs. Descriptive analysis, discriminant analysis, multiple linear regression, ANOVA, homoscedasticity, multicollinearity, reliability, linearity, survey question's normality, and independent errors are conducted to analyze survey data from a sample of 396 IT professionals from various firms in India. The findings show that IT professionals' desire to employ the BCT in EDAs are positively impacted by all the hypothesis except H3 and H8 that has no impact on IT professionals' desire to employ BCT.
Mobile Sink Node with Discerning Motility Approach for Energy Efficient Delay Sensitive Data Communication over Wireless Sensor Body Area Networks
Authors: Reddy R. Anirudh , Ram N. Venkat
Published: September 2023

The sensors nearby the static sink drains their energy resources rapidly, since they continuously involve to build routes in Wireless sensor networks, which are between data sources and static sink. Hence, the sensors nearby the sink having limited lifespan, which axing the network lifetime.The mobile-sink strategy that allows the sink to move around the network area to distribute the transmission overhead to multiple sensor nodes. However, the mobile-sink strategy is often tall ordered practice due to the continuous need of establishing routes between source nodes and the mobile sink (MS) at new position occurred due to its random mobility. In regard to above stated argument, this manuscript proposed a novel energy data transmission strategy which is effective for WSN with mobile sink. Unlike the traditional contributions, which relies on mobile sink with random mobility strategies, the proposal defines a discerning path for mobile sink routing between sectioned clusters of the WSN. The proposal of the manuscript titled “Mobile Sink Node with Discerning Motility Approach (MSDMA) for Energy Efficient Data Communication over WBAN”. The method defined in proposed model sections the target network in to multiple geographical clusters and prioritize these clusters by the delay sensitivity of the data transmitted by the sensor nodes of the corresponding clusters. Further, discriminating these clusters by their delay sensitive priority to define mobile sink route. For estimation of the delay sensitive priority of the clusters, set of metrics are proposed. The experimental study carried on simulation to assess the significance of the suggested method. The performance improvement of the suggested method is ascended through comparative analysis performed against benchmark model under divergent metrics.
Protecting Girls from Harassment and Fraudulent Calls: A Voice-to-Text Approach
Authors: Begum Shaik Salma , Yannam Adilakshmi , Rao T.Nageswara , Chowdary M. Chiranjeevi Chitrasimha , Devi Thota Rishika , PriyaNallamothu Vishnu , Jahnavi Yadla
Published: September 2023

The rise in harassment calls and fraud, particularly targeting girls, has resulted in adverse consequences including psychological distress and, in extreme cases, suicide. Furthermore, fraudulent calls urging individuals to click on malicious links have led to substantial financial losses. This study presents a comprehensive approach to address this challenge for the development of an innovative detection system. Additionally, we introduce a novel prototype that employs a voice-to-text approach to transcribe phone calls, utilizing Natural Language Processing (NLP) techniques as well as Machine Learning (ML) algorithms to identify harassment or fraud-related content. When a malicious call is detected, the system automatically alerts parents or guardians and the nearest police station to prevent tragic outcomes such as suicides among targeted girls and financial fraud. By focusing on both preventive measures and advanced detection, this integrated approach aims to promote a safer communication environment and a more inclusive society.
HR Functions Productivity Boost by using AI
Authors: Kaushik Priyanka , Miglani Sumit , Shandilya Ishaan , Singh Avi , Saini Disha , Singh Aaditya
Published: September 2023

In today's fast-paced world, the Human Resources (HR) department plays a pivotal role in the success of any organization. With a plethora of tasks to manage, the HR team often faces the daunting challenge of screening and selecting the best candidates for various positions. To streamline this process, we propose a novel system that integrates the power of Kruskal algorithm for resume screening, conducting a qualifying test called "BTNT," and psychological testing like Emotional Intelligence to analyze the shortlisted candidates. Our proposed system utilizes a Knapsack approach under Dynamic Programming to suggest the most suitable candidates for HR roles. By automating these tedious HR tasks through Artificial Intelligence (AI), we ensure a faster, more accurate, and cost-effective selection process.

Our research paper presents a detailed analysis of the proposed system's effectiveness and showcases the benefits of adopting this innovative approach. We believe that this cutting-edge system will revolutionize the HR industry by providing an efficient, objective, and unbiased selection process. The BTNT test's incorporation will help identify candidates' technical skills, while the psychological test will highlight their soft skills. This holistic approach ensures that organizations not only hire the best-fit candidates but also create a positive work environment that fosters growth and development. Our research paper is a must-read for any HR professional looking to optimize their recruitment process and gain a competitive edge in the market. With our proposed system's implementation, companies can attract and retain top talent, improve employee productivity, and ultimately increase their efficiency.
Optimizing Robustness and Invisibility in Digital Image Watermarking: A SVM-Based Multi-Level DWT and SVD Approach
Authors: Dixit Ashish , Agarwal R. P. , Sharma B. K.
Published: September 2023

This research introduces a new digital image watermarking approach that utilizes discrete wave transformation (DWT), Support vector machine, and singular value decomposition. The method improves robustness under various assault situations by using the SVM classifier during watermark extraction. Multi-level DWT splits the host picture into sub-bands when embedding, and the coefficients are used as input for SVM. After SVD, the scaling factor embeds the watermark. Comparing the proposed approach to existing research under various attacks, the experimental findings demonstrate that it strikes an equilibrium between robustness and invisibility for watermarks of varying sizes. Support Vector Machine is a contemporary category of machine learning techniques that is extensively employed for the purpose of solving classification problems.
A Review on Tomato Leaf Disease Detection using Deep Learning Approaches
Authors: Vengaiah Cheemaladinne , Konda Srinivasa Reddy
Published: September 2023

Agriculture is one of the major sectors that influence the India economy due to the huge population and ever-growing food demand. Identification of diseases that affect the low yield in food crops plays a major role to improve the yield of a crop. India holds the world's second-largest share of tomato production. Unfortunately, tomato plants are vulnerable to various diseases due to factors such as climate change, heavy rainfall, soil conditions, pesticides, and animals. A significant number of studies have examined the potential of deep learning techniques to combat the leaf disease in tomatoes in the last decade. However, despite the range of applications, several gaps within tomato leaf disease detection are yet to be addressed to support the tomato leaf disease diagnosis. Thus, there is a need to create an information base of existing approaches and identify the challenges and opportunities to help advance the development of tools that address the needs of tomato farmers. The review is focussed on providing a detailed assessment and considerations for developing deep learning-based Convolutional Neural Networks (CNNs) architectures like Dense Net, ResNet, VGG Net, Google Net, Alex Net, and LeNet that are applied to detect the disease in tomato leaves to identify 10 classes of diseases affecting tomato plant leaves, with distinct trained disease datasets. The performance of architecture studies using the data from plantvillage dataset, which includes healthy and diseased classes, with the assistance of several different architectural designs. This paper helps to address the existing research gaps by guiding further development and application of tools to support tomato leaves disease diagnosis and provide disease management support to farmers in improving the crop.
An Enhanced Security Model for Protecting Data Transmission and Communication in Recent IoT Integrated Healthcare Industry Using Machine Learning Algorithm
Authors: Parabrahmachari Sriram , Narayanasamy Srinivasan
Published: September 2023

Different kinds of security need to be applied to various application-centric IoT networks. Safety is one of the most important aspects to be considered regarding user, device, and data. The healthcare industry is a special IoT network fully connected with medical/healthcare IoT devices. The data generated from the IoT devices are transmitted or shared from one hospital to another through the Internet. Healthcare data has more private, medical, and insurance information that intruders can use on the Internet. The intruders misbehave with the patient or the general public registered in the healthcare industry. Some intruders blackmail the patient based on their private/personal information. Healthcare industries and their research team are trying to create a security framework to safeguard the data to avoid these malicious activities. This paper aims to secure and analyze healthcare IoT data using the Support Vector Machine algorithm. It learns the entire dataset, classifies it, and calls the encryption-decryption algorithms (RSA) to secure private data. The proposed SVM and the RSA algorithm are implemented in Python, and the results are verified. The performance of the proposed SVM-RSA is evaluated by comparing its results with the other algorithms.
Justicia social en educación: perspectivas de directores/as de escuelas desaventajadas de Chile
Authors: De la Vega-Rodríguez Luis Felipe , Yáñez-Cifuentes María Teresa
Published: September 2023

The article presents the results of an investigation that identified and analyzed the perceptions of school leaders on some criteria that should be met by institutions operating under the social justice perspective. A multiple-case study was carried out with eight principals who had taken office recently in disadvantaged schools and had completed their first year in that position. The aim was to know their vision regarding aspects related to justice, optimism, empathy, and democracy —presented by other authors— to describe how an educational center works from the perspective of social justice. The results showed discourses that partially incorporated these criteria and indicated a stronger presence of the distribution component over those of recognition and representation, which belong to the concept of social justice.
Bibliometric Analysis of Scientific Production on Visual and Performing Arts Indexed in Scopus: Achievements and Challenges
Authors: Agámez-Llanos Valeria de los Ángeles , León-Cano Juan Fernando , Ordóñez Edward Javier , Rodríguez-Timaná Luis Carlos , Castillo-García Javier Ferney
Published: September 2023

This article explores art disciplines, including visual and performing arts, which allow for creative expression and representation. The progress of these disciplines is closely tied to scientific advancements and the spread of knowledge. Bibliometric studies are a valuable tool for evaluating research indicators in various fields, and this study employs bibliometric analysis to assess scientific production in visual and performing arts from 2016 to 2020. The analysis included 173 journals and 373 articles, and the results showed a growing trend in these fields, but the increase was not statistically significant. Additionally, the study found a high rate of documentary production with single authorship, highlighting the need to encourage collaborative networks. The study concludes that the limited collaboration between countries, the unproductive regions, and the lack of collaborative networks for co-authorship have hindered scientific production in visual and performing arts during the 2016-2020 period.
Acumulação por espoliação, cidades e (geo)grafias do comum no médio curso do rio Tocantins
Authors: Lima Michel de Melo , Alves dos Santos Lais
Published: September 2023

Partindo de reflexões críticas sobre a modernização capitalista da Amazônia, e dos processos de espoliação simultaneamente produzidos, o debate empreendido neste texto aborda o tema das ações coletivas e da produção social de territórios de usos comum na região, tendo como referencial empírico as cidades de Tucuruí e Marabá. Objetiva analisar a relação existente entre a acumulação por espoliação e o enfrentamento protagonizado pelas (geo)grafias do comum, em Tucuruí e Marabá, cidades do médio curso do rio Tocantins, no Estado do Pará. Para tal, utilizou-se do seguinte instrumental de pesquisa: a) revisão teórico-conceitual sobre o processo de acumulação por espoliação, a modernização da Amazônia, os comuns e o debate sobre os movimentos socioterritoriais contemporâneos; b) levantamento e análise bibliográfica, de caráter histórico-geográfico, centrada em Tucuruí e Marabá; c) análise documental referente a intervenções infraestruturais (de geração de energia [hidrelétrica], de logística e mobilidade, de turismo etc.) voltados para o médio curso do rio Tocantins; d) visitas de campo, entrevistas e observação sistemática das dinâmicas socioterritoriais existentes nas cidades selecionadas. A partir dos dados coletados e analisados, constatou-se que o processo de modernização regional, assentando em intervenções infraestruturais, engendra contradições, conflitos e espoliações dos territórios de uso comum ligados aos rios e aos recursos florestais. Por outro lado, essa situação também produz resistências, levantes e insurgências protagonizadas por ações coletivas em defesa dos territórios, um conjunto de (geo)grafias de vida e do comum que se manifestam e contrapõem o desenvolvimento do capital no médio curso do rio Tocantins.
Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids
Authors:   Medical School of Chinese PLA, Beijing 100853, China; Senior Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China, Du Jin-Lin , Wang Tao ,   Medical School of Chinese PLA, Beijing 100853, China, Ye Zi ,   Senior Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China, Li Hong-Yu ,   Medical School of Chinese PLA, Beijing 100853, China; Senior Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China, Li Wen ,   Medical School of Chinese PLA, Beijing 100853, China; Senior Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China, Zeng Quan ,   Stem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing 100850, China, Xi Jia-Fei ,   Stem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing 100850, China, Yue Wen ,   Stem Cell and Regenerative Medicine Lab, Beijing Institute of Radiation Medicine, Beijing 100850, China, Li Zhao-Hui ,   Medical School of Chinese PLA, Beijing 100853, China; Senior Department of Ophthalmology, the Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China
Published: September 2023

AIM: To observe the effect of low oxygen concentration on the neural retina in human induced pluripotent stem cell (hiPSC)-derived retinal organoids (ROs).
METHODS: The hiPSC and a three-dimensional culture method were used for the experiments. Generated embryoid bodies (EBs) were randomly and equally divided into hypoxic and normoxic groups. Photographs of the EBs were taken on days 38, 45, and 52, and the corresponding volume of EBs was calculated. Simultaneously, samples were collected at these three timepoints, followed by fixation, sectioning, and immunofluorescence.
RESULTS: The proportion of Ki67-positive proliferating cells increased steadily on day 38; this proliferation-promoting effect tended to increase tissue density rather than tissue volume. On days 45 and 52, the two groups had relatively similar ratios of Ki67-positive cells. Further immunofluorescence analysis showed that the ratio of SOX2-positive cells significantly increased within the neural retina on day 52 (P<0.05). In contrast, the percentage of PAX6- and CHX10-positive cells significantly decreased following hypoxia treatment at all three timepoints (P<0.01), except for CHX10 at day 45 (P>0.05). Moreover, the proportion of PAX6-/TUJ1+ cells within the neural retinas increased considerably (P<0.01, <0.05, <0.05 respectively).
CONCLUSION: Low oxygen promotes stemness and proliferation of neural retinas, suggesting that hypoxic conditions can enlarge the retinal progenitor cell pool in hiPSC-derived ROs.
Effectiveness of conjunctival bleb scarring by knock-down of heat shock protein 47 in rat model
Authors:   Shaanxi Eye Hospital, Xi’an People’s Hospital (Xi’an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, China, Wang Wei-Wei , Yan Huan-Huan ,   Shaanxi Eye Hospital, Xi’an People’s Hospital (Xi’an Fourth Hospital), Affiliated Guangren Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, China
Published: September 2023

AIM: To evaluate the effectiveness of knock-down of heat shock protein 47 (HSP47) on conjunctival bleb scarring in a rat model and its possible mechanism.
METHODS: Male Sprague–Dawley rats were used for glaucoma filtration surgery (GFS) and were treated with either phosphate buffered solution, shControl, mitomycin C, or sh-HSP47 using a microsyringe immediately after GFS. The morphology of filtering blebs was observed postoperatively. The levels of HSP47 were analyzed at 2, 5, 8, and 11d after GFS via real time quantitative polymerase chain reaction (PCR) and Western blot. The silencing effect of HSP47, the expression of collagen I and III, and the potential signaling pathways of HSP47 during scarification were explored 11d post GFS. The protein levels of transforming growth factor-β1 (TGF-β1), phospho-Smad2 (pSmad2), phospho-Smad3 (p-Smad3), and phospho-p38 (p-p38) were also analyzed using Western blot.
RESULTS: Sh-HSP47 treatment significantly prolonged the functional filtration bleb retention. The levels of HSP47 were increased significantly at 5, 8, and 11d postoperatively compared to the control group (P<0.05, P<0.01, and P<0.001). The levels of HSP47 protein at day 11 postoperatively were significantly down-regulated after HSP47 silencing using sh-HSP47 adenovirus transfection (P<0.01). Expression levels of collagen I and III within the blebs were significantly reduced in the absence of HSP47 (P<0.01). Moreover, the protein levels of TGF-β1, p-Smad2/3, and p-p38 were dramatically inhibited after treatment with sh-HSP47 (P<0.01).
CONCLUSION: The inhibitory effects of HSP47 knock-down on scarring after GFS have the potential to be an efficacious therapeutic option for the treatment of conjunctival bleb scarring.
A novel pathogenic splicing mutation of RPGR in a Chinese family with X-linked retinitis pigmentosa verified by minigene splicing assay
Authors:   Department of Ophthalmology, the Second People’s Hospital of Quzhou, Quzhou 324022, Zhejiang Province, China, Wang Hui-Qin , He Tian ,   Department of Ophthalmology, Children’s Hospital of Hangzhou, Hangzhou 310005, Zhejiang Province, China, Yu Xiao-Feng ,   Department of Ophthalmology, the Second People’s Hospital of Quzhou, Quzhou 324022, Zhejiang Province, China, Huo Ya-Nan ,   Department of Ophthalmology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310020, Zhejiang Province, China
Published: September 2023

AIM: To report a novel splicing mutation in the RPGR gene (encoding retinitis pigmentosa GTPase regulator) in a three-generation Chinese family with X-linked retinitis pigmentosa (XLRP).
METHODS: Comprehensive ophthalmic examinations including best corrected visual acuity, fundus photography, vision field, and pattern-visual evoked potential were performed to identify the disease phenotype of a six-year-old boy from the family (proband). Genomic DNA was extracted from peripheral blood of five available members of the pedigree. Whole-exome sequencing (WES), Sanger sequencing, and pSPL3-based exon trapping were used to investigate the aberrant splicing of RPGR. Human Splice Finder v3.1 and NNSPLICE v0.9 were used for in silico prediction of splice site variants.
RESULTS: The proband was diagnosed as having retinitis pigmentosa (RP). He had severe symptoms with early onset. A novel splicing mutation, c.619+1G>C in RPGR was identified in the proband by WES and in four family members by Sanger sequencing. Minigene splicing assays verified that c.619+1G>C in RPGR would result in the formation of a damaging alternative transcript in which the last 91 bp of exon 6 were skipped, leading to the subsequent deletion of 623 correct amino acids (c.529_619del p.Val177Glnfs*16).
CONCLUSION: We identify a novel splice donor site mutation causing aberrant splicing of RPGR. Our findings add to the catalog of pathological mutations of RPGR and further emphasize the functional importance of RPGR in RP pathogenesis and its complex clinical phenotypes.
Dry eye disease among patients infected with the SARS-CoV-2 Omicron variant: a cross-sectional study
Authors:   Department of Ophthalmology, Daping Hospital, Third Military Medical University, Chongqing 400042, China, Chen Qi-Fang , Chu Han ,   Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resources and Eco-Environment, College of Life Sciences, Sichuan University, Chengdu 610064, Sichuan Province, China, Hu Pan ,   Department of Ophthalmology, Daping Hospital, Third Military Medical University, Chongqing 400042, China, Chen Li ,   Department of Ophthalmology, Daping Hospital, Third Military Medical University, Chongqing 400042, China, Liu Ting ,   Department of Ophthalmology, Daping Hospital, Third Military Medical University, Chongqing 400042, China, Li Chong-Yi ,   Department of Ophthalmology, Daping Hospital, Third Military Medical University, Chongqing 400042, China
Published: September 2023

AIM: To investigate the incidence of dry eye disease (DED) and relevant risk factors among patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.
METHODS: This cross-sectional, observational analysis included 993 patients with corona virus disease 2019 (COVID-19) treated at the National Exhibition and Convention Center (Shanghai) Fangcang Shelter Hospital, from April 10 to May 26, 2022. Totally 944 uninfected control participants were recruited. All participants completed ocular surface disease index (OSDI) questionnaires, and DED symptoms were determined using OSDI scores. The demographic characteristics, length of hospital stay and in nasopharyngeal swabs were performed using questionnaires. SARS-CoV-2 Omicron variant infection was confirmed by nucleic acid-based detection in nasopharyngeal swabs using a 2019-nCoV nucleic acid detection kit. The risk factors for DED symptoms among patients with COVID-19 and control participants were determined by logistic regression analysis.
RESULTS: Patients with COVID-19 showed a higher incidence of DED than controls (64.9% vs 55.1%, P<0.001). SARS-CoV-2 infection [odds ratios (ORs) (95%CI): 1.271 (1.038, 1.556)], use of contact lenses [ORs (95%CI): 9.350 (3.676, 23.783)], history of corneal refractive surgery [ORs (95%CI): 2.047 (1.494, 2.804)], poor sleep quality [ORs (95%CI): 2.657 (2.029, 3.480)], and video display terminal (VDT) use for more than 8h per day [ORs (95%CI): 6.348 (4.720, 8.538)] were found to be risk factors for DED symptoms in patients with COVID-19 as well as controls. For patients with COVID-19, the length of hospital stay [ORs (95%CI): 1.196 (1.134, 1.262)], use of contact lenses [ORs (95%CI): 20.423 (2.680, 155.632)], history of corneal refractive surgery [ORs (95%CI): 2.166 (1.321, 3.553)], poor sleep quality [ORs (95%CI): 3.650 (2.381, 5.597)], and VDT use for more than 8h per day [ORs (95%CI): 7.740 (4.918, 12.180)] were significant risk factors for DED symptoms.
CONCLUSION: Patients with COVID-19 are more prone to develop symptomatic DED. SARS-CoV-2 infection and length of hospital stay are important risk factors for DED symptoms.
Comparative outcomes of the pathogen in cultured Jones tubes used in lacrimal bypass surgery according to follow up periods
Authors:   Department of Ophthalmology, Pusan National University School of Medicine & Medical Research Institute of Pusan National University Hospital, Pusan 49241, Republic of Korea, Park Bo Hyun , Jo Yeon Ji ,   Department of Ophthalmology, Pusan National University School of Medicine & Medical Research Institute of Pusan National University Hospital, Pusan 49241, Republic of Korea, Lee Jong Soo ,   Department of Ophthalmology, Pusan National University School of Medicine & Medical Research Institute of Pusan National University Hospital, Pusan 49241, Republic of Korea
Published: September 2023

AIM: To evaluate the pathogens in cultured Jones tubes used in lacrimal bypass surgery according to the postoperative periods and to obtain data for the prevention of infection of functional lacrimal stent invention.
METHODS: Totally 71 patients (81 eyes) who underwent the removal of Jones tubes were enrolled in study. All the removed Jones tubes were cultured for bacterial and fungal identification and tested for bacterial antibiotic sensitivity. The results were analyzed according to the duration of the inserted Jones tube after lacrimal bypass surgery.
RESULTS: Of the 81 eyes, bacteria were isolated from 69 eyes (85.2%) and fungi from 6 eyes (7.4%). Among 69 eyes, 40.6% showed Staphylococcus aureus (S. aureus), 11.6% were Pseudomonas aeruginosa (P. aeruginosa). Gram-positive bacteria were isolated more than Gram-negative bacteria, but Gram-negative bacteria showed a higher incidence in the Jones tube implanted for over 10y (P=0.035). The antibiotic sensitivity test showed that 46.4% of S. aureus were resistant to oxacillin. In terms of antibiotics commonly used in ocular clinical practice, vancomycin was sensitive to S. aureus and Streptococcus pneumoniae (S. pneumoniae), amikacin responded to P. aeruginosa and Proteus mirabilis (P. mirabilis). Trimethoprim/sulfamethoxazole (TMP/SMX) was all sensitive to S. aureus, S. pneumoniae and P. mirabilis except P. aeruginosa.
CONCLUSION: S. aureus is the most commonly found organism in the Jones tube after lacrimal bypass surgery, and 46.4% of them are methicillin-resistant S. aureus (MRSA), sensitive to vancomycin. Especially, P. mirabilis responded with amikacin is dominantly detected in the Jones tubes implanted for more than 10y.
Effect of visual perception training on binocular visual function reconstruction in patients after strabismus surgery
Authors:   School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China, Su Yu , Wang Tao ,   Department of Ophthalmology, Anhui Provincial Children’s Hospital, Hefei 230041, Anhui Province, China, Wang Qin-Mei ,   School of Optometry and Ophthalmology, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China
Published: September 2023

AIM: To explore the effect of visual perception learning software training (VPT) on binocular visual function reconstruction in children with intermittent exotropia after strabismus surgery.
METHODS: Ninety children with intermittent exotropia admitted to our hospital from June 2018 to December 2018 were included, and randomly divided into VPT and control groups. Children in the control group received basic binocular vision training, while those in the VPT group received VPT after strabismus surgery. Tertiary visual function, visual perception function, Newcastle Control Score (NCS), and ocular position retraction rate were compared at 3 and 12mo after the surgery.
RESULTS: At 3 and 12mo after the surgery, the proportion of simultaneous perception, binocular fusion version and binocular stereo vision in the VPT group was conspicuously higher than that in the control group (P<0.05). After the vision training, the binocular visual perception functions of children in both groups were significantly improved compared with that before training (P<0.05). Interestingly, the grating sharpness, texture perception and texture motion perception in the VPT group were dramatically better than control group (P<0.01). The NCS in the VPT group was significantly lower than that in the control group (P<0.05). The ocular position retraction rate in the VPT group was significantly lower than that in the control group at 12mo (8.89% vs 26.67%, P=0.03).
CONCLUSION: VPT effectively promotes binocular visual function reconstruction in intermittent exotropia children after strabismus surgery and reduces the strabismus severity and ocular position retraction rate.
Three-dimensional bioprinting in ophthalmic care
Authors:   Al-baha University, Applied Medical Science, Al-Aqiaq, AlBaha 4781, Saudi Arabia, Al-Atawi Saleha
Published: September 2023

Three-dimensional (3D) bioprinting is widely used in ophthalmic clinic, including in diagnosis, surgery, prosthetics, medications, drug development and delivery, and medical education. Articles published in 2011–2022 into bioinks, printing technologies, and bioprinting applications in ophthalmology were reviewed and the strengths and limitations of bioprinting in ophthalmology highlighted. The review highlighted the trade-offs of printing technologies and bioinks in respect to, among others, material type cost, throughput, gelation technique, cell density, cell viability, resolution, and printing speed. There is already widespread ophthalmological application of bioprinting outside clinical settings, including in educational modelling, retinal imaging/visualization techniques and drug design/testing. In clinical settings, bioprinting has already found application in pre-operatory planning. Even so, the findings showed that even with its immense promise, actual translation to clinical applications remains distant, but relatively closer for the corneal (except stromal) tissues, epithelium, endothelium, and conjunctiva, than it was for the retina. This review similarly reflected on the critical on the technical, practical, ethical, and cost barrier to rapid progress of bioprinting in ophthalmology, including accessibility to the most sophisticated bioprinting technologies, choice, and suitability of bioinks, tissue viability and storage conditions. The extant research is encouraging, but more work is clearly required for the push towards clinical translation of research.
NEW RECORDS OF WEEVILS (COLEOPTERA, CURCULIONIDAE) IN THE ODESA REGION
Authors: Serhieiev L. A. , Nazarenko V. Yu. , Uzhevska S. P. , Burykina S. I.
Published: September 2023

Actuality. Considering the fact that some representatives of weevils damage agricultural crops and forest plantations, while others are phytophages of wild plants and weeds, it is advisable to study their species composition and distribution in agrocenoses.
Problem. Investigations of the species composition of weevils in the fields of the Odesa State Agricultural Research Station of the NAAS.
Methods. Counting of weevils was carried out according to generally accepted methods. Selection of herpetobiont insects was carried out using Barber’s traps, hortobionts – mowing with an entomological net.
Results. In 2022, 18 species of weevils were registered in the fields of winter pea and winter wheat of the Odesa State Agricultural Research Station of the IKOA of the NAAS, of which five were found that had not previously been noted in the Odesa region: Ethelcus denticulatus (Schrank, 1781), Stenocarus cardui (Herbst, 1784), Gymnetron rotundicolle (Gyllenhal, 1838), Hypera melancholica (Fabricius, 1792), Hypera viciae (Gyllenhal, 1813). New record of Alcidodes karelinii (Boheman,1844) is published after 12 years.
HISTORIAN VOLODYMYR MYKOLAYOVYCH YASTREBOV (1855–1898): ODESA UNIVERSITY YEARS
Authors: Muzychko Oleksandr
Published: September 2023

It is necessary to research the biographies of historians. This makes it possible to establish a connection between the features of the life path of historians and their historical views, to study the social component in the development of science. The main thesis of the article is the fact that the development of a scientist is largely determined by the characteristics of his formation as a person, primarily in a higher educational institution.
The purpose of this article is to prove this thesis based on the study of the early stage of the life of the famous historian who worked for many years in the city of Elizavetgrad (today Kropyvnitsky) Volodimir Mykolayovych Yastrebov (1855-1898). In 1872-1877 he studied and defended his Ph.D. thesis at the Odessa Novorossiysk University. The historiographic base of our article consists of a number of articles and books. The main contribution to the biography of V. M. Yastrebov was made by the Kirovograd (Kropyvnytskyi) historians. They often mentioned the Odesa stage of the scientist's life, but did little to concretize the circumstances of his studies at the university.
The sources of our article are narrative and act documents. The most important sources are kept in the State Archives of the Odessa region. We have identified such important sources as the memoirs of V. M. Yastrebova about studying at the Odessa University, his thesis about the sixth crusade. Thus, there is a sufficient base of sources for the reconstruction of the student's years of the historian. The main methods of our research are comparative, genetic, microhistorical, and biographical.
So the conclusion to be drawn is Odesa University was of great importance for the formation of the personality of V. M. Yastrebov. The greatest influence on the formation of him as a scientist had such talented teachers as V. I. Grygorovych, Р. В. Orbynsky, P. K Brun, I. S. Nekrasov. In addition to university teachers, of great importance at that time was a high school teacher O. I. Markevych.
Communication with supporters of Ukrainian culture V. I. Grygorovych, O. I. Markevych formed a nice image of V. M. Yastrebov is a russian with an interest in the Ukrainian people and culture. Studying in Odesa laid the foundations of cooperation V. M. Yastrebov with the Odesa scientific environment throughout his later life.
RETURN TO HISTORY: BY THE CALL OF THE SOUL
Authors: Dyomin Oleg
Published: September 2023

One of the ancient and stable traditions is the communication of graduates and the alma mater. It takes different forms and for different times. It can be said unequivocally that such contacts take place regardless of the years of study, further profession, place of residence, the level of communication during the student years and so on. Memory is a whimsical thing, and sometimes things are preserved that once had a completely different, sometimes negative, color. But the positive of the student years outweighs everything else and there is a desire to meet their past. Professional and personal connections, advice or assistance are often needed. However, very rare offers of cooperation from former students of the Faculty of History.
Análise de invasão biológica e uso de diferentes metodos de controle de Leucaena leucocephala (Lam.) de Wit
Authors: Eleutério Wellerson Juliano , Lacorte Gustavo Augusto , Suzuki Ludimilla Portela Zambaldi Lima , Duarte Neimar Freitas
Published: September 2023

Invasões biológicas têm recebido cada vez mais atenção de pesquisadores em todo o mundo e têm se tornado cada vez mais evidente a necessidade de medidas de prevenção. A leucena (Leucaena leucocephala (Lam.) de Wit) é uma espécie arbustivo arbórea que se encontra na lista das 100 espécies invasoras mais agressivas do planeta. O objetivo deste trabalho foi estudar a invasão biológica e controle da leucena no município de Arcos/MG no Brasil. Para a realização da avaliação da ocupação do solo ocorridas pela Leucena dos anos de 2005 a 2017, foram utilizadas imagens dos satélites Landsat 7 e 8. Para cada ano avaliado foram gerados mapas temáticos de ocupação do solo da área de expansão da espécie exótica, a fim de quantificar a área total invadida, para a melhor visualização das áreas ocupadas e das diferentes classes de vegetação nas imagens Landsat, foram gerados mapas com o uso do NDVI (Normalized Difference Vegetation Index). A média de expansão anual da leucena na área foi de 0,112 ha/ano. O controle da espécie foi avaliado utilizando delineamento experimental com oito tratamentos e três repetições em blocos casualizados, sendo os seguintes tratamentos: picloran+2,4D (288 +1.080 g ha-1), triclopir-butotílico (5 L p.c.ha-1), glifosato (2,40 kg i.a.ha-1), isolados e os mesmos aplicado posteriormente no toco, após corte raso. O melhor controle se deu através da realização de corte raso e aplicação de picloram + 2,4D sobre os tocos, atingindo média de 80% de controle da espécie em 360 dias após o tratamento (DAT).
Investigating the Causes of Swim Instructor Turnover in the Aquatics Industry
Authors: Butson Michael , Du Eric , Jeanes Ruth , Tower John
Published: September 2023

Employees are said to be the backbone of any organization. The aquatic industry is one of the largest employers in the sport and recreation sector and is rapidly growing, with career opportunities available to a diverse workforce for individuals of all ages and backgrounds (Sherry et al., 2021). The aquatics industry is experiencing increased voluntary and dysfunctional swim instructor turnover. Employee turnover is the rate at which individuals leave an organization, and high employee turnover can be disruptive and costly for management, employees, and customers. High swim instructor turnover undermines the effectiveness of swim instruction and exacerbates the risk of swimming-related injuries and drowning. Therefore, a critical first step is to better understand the reasons for turnover to address concerns with recruitment and swim instructor retention. High employee turnover should not be excused as an inherent characteristic of the aquatics industry, but rather the result of individual and systemic factors. As swim instructor turnover is an under-researched issue, we adopted an exploratory approach to this research. We utilized a qualitative research approach, collecting data through a series of semi-structured interviews, to explore the reasons for swim instructor turnover with nineteen (58% male, 42% female) former swim instructors. Most respondents reported a combination of reasons that ultimately led to separation from their position. A deductive analysis of the interview data revealed the reasons for turnover among former swim instructors: swim instructing as a temporary role, limited career progression, failing to understand and underestimating the swim instructor working environment, and a negative view of management. This research extends human resource management literature across the aquatics industry by identifying reasons for turnover from the perspective of former swim instructors. When swim instructors depart, it can disrupt existing relationships and workflows, and makes it so that fewer individuals get the benefits associated with learning to swim. These results suggest managers would benefit from implementing appropriate retention strategies to retain swim instructors, realistic job preview, swim instructor training and personal development, and exit interviews.
The concept of constructing a stoichiometric turbojet engine
Authors: Pismennyi V.L.
Published: September 2023

The paper proposes an alternative approach to design and development of the supersonic and hypersonic gas turbine engines. Currently, the leading aircraft engine companies, such as General Electric, United Technologies, Rolls-Royce and SNECMA Group, are pursuing the active technical policy in creating the new generation aircraft gas turbine engines (VAATE, IHPET, UEET, VITAL and other programs). At the same time, dynamics in such engines development demonstrates that timing of alteration in the aircraft engines generations is lengthening, and boundaries between generations are becoming more conditional indicating a systemic crisis. To maintain stable operation of the gas turbine engines, aircraft compressors are regulated. To this end, they are made double-circuit and multi-shaft, which makes it possible to maintain stable operation at subsonic and moderate supersonic flight speeds, but appears to be an obstacle in their further growth. It is proposed to refuse regulating a compressor as a method of ensuring the engine stable operation and to pass to regulating the turbine as an approach to maintain the compressor given operation mode. In order to exclude the compressor stages mismatch as a phenomenon, it is necessary that the compressor operating mode, regardless of the engine operating mode, remains calculated or close to it. In accordance with this principle, the gas-dynamic appearance of a gas turbine engine was formed as a stoichiometric single-circuit turbojet engine with the single-stage adjustable turbine. The engine control program was determined by dependence of the reduced rotation rate on the outside air stagnation temperature and was implemented by changing the gas temperature in front of the turbine and the pressure drop in it. Transition to a new concept of constructing a gas turbine engine opens new prospects, expands the flight speed range up to hypersonic, increases the gas-dynamic efficiency (overall efficiency of more than 40%) and reduces (by more than 2 times) the specific mass. The key condition in implementing the concept should include creation of new technologies making it possible to increase the gas temperature in front of the turbine up to 2300–2400 K.
Key issues in creating inflatable braking devices for removal of the failed satellites into the atmosphere dense layers Part 3. Assessment of the shell resistance to impacts of micrometeorites and elements of small space debris
Authors: Reznik S.V. , Mikhailovskiy K.V. , Abramova E.N.
Published: September 2023

Equipping small spacecraft with the inflatable braking devices is one of the promising approaches to reducing pollution of the near-Earth space from space debris. Principle of the inflatable braking system operation is quite simple: pressurized gas is supplied at the right moment into the shell compactly installed inside the shipping container, the shell opens, and due to its large cross-sectional area, the braking force increases contributing to a decrease in the flight velocity. Because of the weight and size restrictions, the braking system inflatable shell should be made of a thin polymer film. Obviously, such a shell resistance to impacts from micrometeoroids and small space debris would determine viability of the very concept of the inflatable braking devices. Calculation and theoretical estimates of the polymer shells resistance to the aluminum and water ice particles with diameter of 1…30 µm in the range of velocities of 0.5…7.0 km/s were made. It is shown that at the motion velocity of more than 3 km/s, particles with properties of aluminum with diameter of 10 µm or more are posing danger to the shell of a polymer film. Probability of the shell collision with a particle with diameter of 10 ?m in the 300 km high orbit reaches 0.25, which indicates the need for its reinforcement to maintain the shape in the event of a local puncture.
Changes in the content of aminonitrogen and the activity of aminotransferases in saliva in lymphomas
Authors: Dyachenko E. I. , Bel’skaya L. V.
Published: September 2023

Background. The relevance of studying changes in the activity of metabolic enzymes in saliva in lymphomas lies in the non-invasive method of research, the search for new ways in the diagnosis of oncology to detect the disease in the early stages, as well as to obtain a complete picture of the course of the pathological process. The activity of certain biochemical enzymes is significantly higher in saliva than in blood serum. In addition, saliva is a less hazardous environment for laboratory testing than blood, which reduces the risk of infection for medical personnel. Objective. The aim of this work was to search for biochemical markers in saliva in Hodgkin’s and non-Hodgkin’s lymphomas, the value of which was statistically significantly different from the values of the same markers among healthy subjects included in the control group. Design and methods. In the case-control study, volunteers were divided into 2 groups: the main group, with a histologically confirmed diagnosis of Hodgkin’s lymphoma (53 people) or non-Hodgkin’s lymphoma (82 people) and the control group (135 people), apparently healthy individuals. Inclusion in groups occurred in parallel. All participants underwent a biochemical study of saliva to determine the content of amine nitrogen, the activity of enzymes (AlAT, AsAT, GGT, alkaline phosphatase). The patients of the main group were recruited on the basis of the Clinical Oncological Dispensary (Omsk, Russian Federation). Results. A significant increase in amino nitrogen (p < 0,0084), ALT (p < 0,0205), AST (p < 0,0047), GGT (p<0,0291) was found in the group of patients diagnosed with non-Hodgkin’s lymphoma, compared with subjects from the control group. Conclusion. A preliminary hypothesis was put forward that aminotransferases such as ALT, AST and GGT can be used not only as indicators of liver damage. A change in the activity of amine transferases with a simultaneous increase in the activity of amino nitrogen may reflect a pronounced redistribution of nitrogen in the body for the synthesis of new non-essential amino acids that are necessary for neoplastic cells as structural components for their growth and proliferation. This work also confirms that saliva is an informative diagnostic liquid that can be used in the routine practice of a clinician.