bluuebunny/crossref_metadata_2025 huggingface dataset:
Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer
Authors: Volpato Milene , Cummings Michele , Shaaban Abeer M. , Abderrahman Balkees , Hull Mark A. , Maximov Philipp Y. , Broom Bradley M. , Hoppe Reiner , Fan Ping , Brauch Hiltrud , Jordan V. Craig , Speirs Valerie
Published: October 2020

Aim: Tamoxifen (TAM) resistance remains a clinical issue in breast cancer. The authors previously reported that 15-hydroxyprostaglandin dehydrogenase (HPGD) was significantly downregulated in tamoxifen-resistant (TAMr) breast cancer cell lines. Here, the authors investigated the relationship between HPGD expression, TAM resistance and prediction of outcome in breast cancer.
Methods: HPGD overexpression and silencing studies were performed in isogenic TAMr and parental human breast cancer cell lines to establish the impact of HPGD expression on TAM resistance. HPGD expression and clinical outcome relationships were explored using immunohistochemistry and in silico analysis.
Results: Restoration of HPGD expression and activity sensitised TAMr MCF-7 cells to TAM and 17β-oestradiol, whilst HPGD silencing in parental MCF-7 cells reduced TAM sensitivity. TAMr cells released more prostaglandin E2 (PGE2) than controls, which was reduced in TAMr cells stably transfected with HPGD. Exogenous PGE2 signalled through the EP4 receptor to reduce breast cancer cell sensitivity to TAM. Decreased HPGD expression was associated with decreased overall survival in ERα-positive breast cancer patients.
Conclusions: HPGD downregulation in breast cancer is associated with reduced response to TAM therapy via PGE2-EP4 signalling and decreases patient survival. The data offer a potential target to develop combination therapies that may overcome acquired tamoxifen resistance.
Efficiency Of STMIK Hang Tuah Pekanbaru Stationery Inventory Office Using Monte Carlo Method
Authors: Ordila Rian
Published: October 2020

Inventory management in Office Stationery needs (ATK) is instrumental in supporting administrative activities. Not terinvetaris well, resulting in the use of goods is not optimal and increase spending on this ATK. For that required a system that can manage this ATK supplies. so that in the prediction of ATK inventory can coordinate and minimize expenditure of STMIK Hang Tuah Pekanbaru expenditure. The data obtained in this research is ATK At High School of Information and Computer Management (STMIK) Hang Tuah Pekanbaru sourced from Head of Equipment Section such as paper type A4 and F4, Paperclip, Map and Printer Ink. ATK is always experiencing shortage or also excess needs. With the Monte Carlo Method, STMIK Hang Tuah Pekanbaru will be able to determine the Pattern of ATK Supplies requirement in STMIK Hang Tuah Pekanbaru and the method can give a decision in determining the pattern of ATK request that will be requested to the employee. The result of the experiment of this method is to obtain the average number of procurement requests and the average number of procurement. Estimates of the Monte Carlo simulation strategic plan that has been done will yield an estimated information on the average amount of procurement as 16 packs and the estimated average monthly expenditure of Rp 21,333.- With the amount of calculations obtained then the Office Stationery to be purchased can be estimated and inventory can be provided to meet the demand for campus needs in 2018
Dual task interference on early perceptual processing
Authors: Duncan Justin , Roberge Amélie , Fortier-Gauthier Ulysse , Fiset Daniel , Blais Caroline , Brisson Benoit
Published: October 2020

When two tasks, Task 1 and Task 2, are conducted in close temporal proximity and a separate speeded response is required for each target (T1 and T2), T2 report performance decreases as a function of its temporal proximity to T1. This so-called psychological refractory period (PRP) effect on T2 processing is largely assumed to reflect interference from T1 response selection on T2 response selection. However, interference on early perceptual processing of T2 has been observed in a modified paradigm, which required changes in visual-spatial attention, sensory modality, task modality, and response modality across targets. The goal of the present study was to investigate the possibility of early perceptual interference by systematically and iteratively removing each of these possible non perceptual confounds, in a series of four experiments. To assess T2 visual memory consolidation success, T2 was presented for a varying duration and immediately masked. T2 report accuracy, which was taken as a measure of perceptual—encoding or consolidation—success, decreased across all experimental control conditions as T1–T2 onset proximity increased. We argue that our results, in light of previous studies, show that central processing of a first target, responsible for the classical PRP effect, also interferes with early perceptual processing of a second target. We end with a discussion of broader implications for psychological refractory period and attentional blink effects.
Determinantes sociales que condicionan la actividad sexual precoz de los adolescentes
Authors: Fernández Tapia Sonia
Published: October 2020

Objetivo. Analizar los determinantes sociales que condicionan la actividad sexual precoz de los adolescentes. Métodos. Estudio cuantitativo, descriptivo, explicativo y transversal. La muestra estuvo constituida por 254 estudiantes de 14 a 18 años de edad, a quienes se aplicó un cuestionario que evaluó las dimensiones personales, familiares, contextuales y el inicio de la actividad sexual. Para el análisis de la relación entre variables se utilizó la prueba estadística ji-cuadrado y modelo de regresión lineal múltiple. Resultados. Seidentifcaron los condicionantes personales, la edad de inicio sexual, la falta de uso de anticonceptivos y el poco conocimiento de los signos y síntomas de las infecciones de transmisión sexual. Entre los determinantes familiares, el grado de instrucción de los padres, el apoyo de la mamá y la violencia verbaly física aparecen como los que tienen una asociación signifcativa. Junto a la falta de hábito en acudir a los servicios de salud, los programas de televisión y los amigos aparecen como los que más promueven el inicio de la actividad sexual precoz. Conclusión. Los determinantes personales, familiares y contextuales inﬂuyen signifcativamente en el inicio de la actividad sexual de los adolescentes, atentando en la salud sexual y reproductiva de estos.
Cogestión en los Servicios de Salud
Authors: Montes Gómez Berenice , Martel Carranza Christian Paolo , Torero Solano de Martel Nathalie Zinzia
Published: October 2020

Objetivo. Analizar el involucramiento de las Asociaciones de Comunidad Local de Administración de Salud (ACLAS), del Gobierno Regional de Huánuco. Métodos. Estudio descriptivo con la aplicación de cuestionarios (método cuantitativo). La población de la investigación estuvo constituida por los miembros involucrados en la cogestión (Asamblea General, Consejo Directivo y Gerencia) de las 60 ACLAS vigentes, pertenecientes jurisdiccionalmente a la Unidad Ejecutora Huánuco, 2017 y la muestra estuvo conformada por 132  miembros pertenecientes a 22 ACLAS vigentes. Resultados. Se encontró una relación positiva entre la cogestión y la gestión de los servicios de salud, siendo los recursos humanos (0,53) y el ejercicio de las funciones administrativas (0,43) las que mayor relación tuvieron con la gestión. De la misma manera, la falta de compromiso de las autoridades locales del Consejo Directivo para la planifcación del quehacer de las ACLAS o para facilitar los procesos de programación de actividades del Plan de Salud Local (PSL) resaltan en el estudio. Conclusión. La investigación identifca los factores de la gestión de recursos humanos, tales como la cantidad insufciente de personal de salud para la atención de los usuarios y la falta de capacitación y asistencia técnica de los mismos en relación directa con la gestión sanitaria de los establecimientos de salud.
ANALISIS KESULITAN GURU MADRASAH IBTIDAIYAH DALAM PENILAIAN PEMBELAJARAN TEMATIK KURIKULUM 2013
Authors: Dian Eka Lestari  , Zahrotul Luthfiyah
Published: October 2020

This study aims to explain and analyze the difficulties of teachers in carrying out the 2013 thematic learning assessment curriculum, the factors that cause teachers' difficulties in carrying out the 2013 thematic learning assessment curriculum and the efforts that MI teachers can do to overcome the difficulties in evaluating the 2013 thematic learning curriculum in MIM Kendalkemlagi. This type of research is a case study research with a qualitative approach. Data collection methods used were interviews, observation and documentation. Data analysis techniques used are data reduction, data presentation and conclusion drawing. The technique of determining the validity and validity of data uses triangulation of techniques and sources. The results of this study indicate that the difficulties experienced by MI teachers in carrying out the 2013 curriculum thematic learning assessment include the preparation of an assessment format and assessment instruments; understand children with a variety of material from several content subjects combined in one theme; understanding questions to students who are still not fluent in reading; KI and KD mapping process, assessment process, learning process, and determining the assessment tools used. Efforts made by the teacher to overcome these difficulties are by attending the 2013 curriculum training, communicating and consulting a lot of parties both the school principal, vice curriculum or peers or other teachers.
PENGARUH KREATIVITAS GURU TERHADAP PRESTASI BELAJAR PESERTA DIDIK MATA PELAJARAN MATEMATIKA
Authors: Rofiatun Nisa’  , Sukiyanto  , Latifatul Mujtahidah
Published: October 2020

The purpose of this study was to: determine the level of teacher creativity in teaching, the level of student learning achievement, the effect of teacher creativity on student achievement in mathematics class V at MI Thoriqotul Hidayah Centini. This study uses a quantitative approach with a sample of 24 students. Data collection techniques using questionnaires and documentation. Data analysis techniques include descriptive analysis, simple linear regression analysis, t test and coefficient of determination. The results showed that the creativity of teachers was classified as moderate with a percentage of 87.5%. It meant that the teacher was quite creative in providing ideas that could make students motivated to learn, the learning achievement of class V students was moderate with a percentage of 50%. This means that students have been able to show changes including their ability to think and their skills in mathematics, from the results of t test regression analysis obtained  >  (3,438 > 1,717) then Ha is accepted and it can be concluded that partially the teacher creativity variable has a significant effect towards student learning achievement means the better the teacher's creativity the better the student's learning achievement.
INTERNALISASI BUDAYA PESANTREN PADA KURIKULUM SEKOLAH
Authors: Muhammad Sya’roni
Published: October 2020

The culture of pesantren is the work, feeling and creation of goods, regulations, ideas, activities, language, behavior, beliefs and habits in boarding schools that have been mutually agreed upon. Among the pesantren cultures that can be internalized in the school curriculum include the Deepening of the religious sciences; Mondok; Obedience; Exemplary; Piety; Independence; Discipline; Simplicity; Tolerance; Qana'ah; Humble; Fortitude; Solidarity / Please help; Sincerity; Istiqamah; Society; Cleanliness. The internalization of pesantren culture is integrated into all school activities, both intracurecular and extra-curricular activities.
Yaygın Anksiyete Bozukluğunda Nötrofil Lenfosit Oranı
Authors: ÖRÜM Mehmet Hamdi
Published: October 2020

Amaç: Yaygın anksiyete bozukluğu (YAB)’ndaki nötrofil lenfosit oranı (NLO) ve monosit lenfosit oranı (MLO) değerlerini incelemeyi amaçladık.
Yöntem: Bu retrospektif çalışmada YAB tanısı alan hastaların (n=43) NLO ve MLO değerleri sağlıklı olguların (n=35) verileri ile karşılaştırıldı.
Bulgular: Hasta ve sağlıklı kontrol grubu, kadınlardan oluşuyordu ve ortalama yaşları benzerdi (p=0,287). Nötrofil sayısı (p<0,001), nötrofil yüzdesi (p=0,008) ve NLO (p=0,011) hasta grubunda anlamlı olarak yüksekti. Lenfosit yüzdesi kontrol grubunda anlamlı olarak daha yüksekti (p=0,018). Monosit sayısı, lenfosit sayısı, monosit yüzdesi ve MLO gruplar arasında benzerdi (p>0,05).
Sonuç: Bu çalışma, YAB’da nötrofil ilişkili parametrelerin artışını göstermesi bakımından önemlidir.
Plasenta invazyon anomalisi olan ve olmayan plasenta previa vakalarında risk faktörleri, yönetim ve perinatal sonuçlar
Authors: KALE İbrahim , ULUUTKU Gizem Berfin , ERGİN Başak
Published: October 2020

Amaç İnvazyon anomalisi olan ve olmayan plasenta previa vakalarında risk faktörlerinin belirlenmesi, yönetim şekillerinin, maternal ve yeni doğan sonuçlarının karşılaştırılmasıdır. Gereç ve Yöntemler: 2014-2019 yılları arasında hastanemizde doğum yapan 34199 hastanın dosyası retrospektif olarak tarandı. İnvazyon anomalisi olan ve olmayan tüm plasenta previa vakalarının bilgilerine ulaşıldı. Bulgular: 34199 hastanın 15’inde invazyon anomalisi olan (%0,04 ) ve 85’inde invazyon anomalisi olmayan (%0,24) toplamda 100 tane plasenta previa vakası (%0,29) saptanmıştır. Her iki grup arasında; anne yaş ortalaması, geçirilmiş küretaj, abortus öyküsü, IVF gebeliği, GDM, IUGR ve HT ile ilişkili hastalık açısından bir fark yoktu. Gravida ve parite sayısı ile geçirilmiş sezaryen doğum öyküsü invazyonu olan grupta anlamlı oranda fazlaydı (sırasıyla p=0,005, p=0,01 ve p
An Exact, Generalized Laplace Resonance in the HR 8799 Planetary System
Authors: Goździewski Krzysztof , Migaszewski Cezary
Published: October 2020

A system of four super-Jupiter planets around HR 8799 is the first multiplanet configuration discovered via the direct imaging technique. Despite over a decade of research, the system’s architecture is still not fully resolved. The main difficulty comes from a still narrow observing window of ∼20 yr that covers small arcs of orbits with periods from roughly 50 to 500 yr. Soon after the discovery, it became clear that unconstrained best-fitting astrometric configurations self-disrupt rapidly due to strong mutual gravitational interactions between the companions of ≃10 Jupiter mass. Recently, we showed that the HR 8799 system may be long-term stable when locked in a generalized Laplace 8:4:2:1 mean-motion resonance (MMR) chain, and we constrained its orbits through the planetary migration. Here we qualitatively improve this approach by considering the MMR in terms of an exactly periodic configuration. This assumption enables us to construct for the first time the self-consistent N-body model of the long-term stable orbital architecture using only available astrometric positions of the planets relative to the star. We independently determine the planetary masses, which are consistent with thermodynamic evolution, and the parallax overlapping to 1σ with the most recent Gaia DR2 value. We also determine the global structure of the inner and outer debris disks in the [8, 600] au range, consistent with the updated orbital solution.
The Lyman Continuum Escape Survey: Connecting Time-dependent [O iii] and [O ii] Line Emission with Lyman Continuum Escape Fraction in Simulations of Galaxy Formation
Authors: Barrow Kirk S. S. , Robertson Brant E. , Ellis Richard S. , Nakajima Kimihiko , Saxena Aayush , Stark Daniel P. , Tang Mengtao
Published: October 2020

Escaping Lyman continuum photons from galaxies likely reionized the intergalactic medium at redshifts z ≳ 6. However, the Lyman continuum is not directly observable at these redshifts and secondary indicators of Lyman continuum escape must be used to estimate the budget of ionizing photons. Observationally, at redshifts z ∼ 2–3 where the Lyman continuum is observationally accessible, surveys have established that many objects that show appreciable Lyman continuum escape fractions f
esc also show enhanced [O iii]/[O ii] (O32) emission line ratios. Here, we use radiative transfer analyses of cosmological zoom-in simulations of galaxy formation to study the physical connection between f
esc and O32. Like the observations, we find that the largest f
esc values occur at elevated O32 ∼ 3–10 and that the combination of high f
esc and low O32 is extremely rare. While high f
esc and O32 often are observable concurrently, the timescales of the physical origin for the processes are very different. Large O32 values fluctuate on short (∼1 Myr) timescales during the Wolf–Rayet-powered phase after the formation of star clusters, while channels of low absorption are established over tens of megayears by collections of supernovae. We find that while there is no direct causal relation between f
esc and O32, high f
esc most often occurs after continuous input from star formation-related feedback events that have corresponding excursions to large O32 emission. These calculations are in agreement with interpretations of observations that large f
esc tends to occur when O32 is large, but large O32 does not necessarily imply efficient Lyman continuum escape.
Intime et singulier en consultation thérapeutique
Authors: Chervet Emmanuelle
Published: October 2020

En introduction à trois textes élaborés à partir de la clinique de consultation thérapeutique dans un cmp , l’auteur rappelle quelques aspects de cette pratique qui vise à permettre la survenue de contenus singuliers dont l’expression partiellement agie sur la scène de la consultation réalise une élaboration différente pour chaque personne. Une qualité d’intimité peut accompagner ce processus lorsque la compulsion à agir et interagir peut se détendre et autoriser une séparation des espaces psychiques de chacun, ce qui réclame, selon les conjonctures, différents modes d’intervention du thérapeute. Les textes du dossier présentent quelques-unes de ces occurrences.
Clivage de loyauté : d’une parole pour trois à une parole à soi
Authors: Girardon Marie
Published: October 2020

Dans un contexte de discorde fondamentale entre les parents concernant l’éducation de leur enfant, nous verrons comment ce dernier se retrouvera contraint à des aménagements psychiques radicaux pour tenter de rester en contact avec les deux systèmes parentaux contradictoires voire paradoxaux. Nous considérerons la mise en place d’un « clivage de loyauté » comme une solution entravant le déploiement de la subjectivité propre de l’enfant. Dans ce contexte, nous verrons comment la démarche du thérapeute dans la réalité extérieure se révèlera être un événement signifiant dans le processus thérapeutique et probablement une première étape essentielle à l’instauration d’un espace intime préservé pour l’enfant.
Aux prises avec la construction de l’intériorité dans l’anorexie mentale
Authors: Morel Alexandre
Published: October 2020

Dans un évitement de la réalité psychique que dictent l’urgence comportementale et spectaculaire du symptôme, mais aussi le surinvestissement de la perception et diverses modalités de l’externalisation, patients et cliniciens peuvent se trouver comme privés de leurs ressources représentationnelles pour penser l’anorexie et les conflits internes qui la sous-tendent. Les actions psychiques qui convoquent le jeu, le déplacement en diverses scènes, l’objectalisation et la sexualisation sont ici décrites. À travers deux exemples cliniques, diverses manifestations d’une insupportable intériorité seront évoquées avant d’envisager les voies analysantes et soignantes d’un retour vers « l’intérieur », d’une associativité retrouvée qui brise l’univoque du symptôme, ouvre une scène pour le sexuel et la diversité de ses conflits.
It’s alive and (side-)kicking! Frankenstein’s double acts
Authors: Baillon Jean-François
Published: October 2020

In Mary Shelley’s novel, Frankenstein has no assistant and gives birth to the creature alone. In the film versions, however, he is often supported by one or several assistants. According to the logic of the supplement, what looks like a mere adjunct turns out to double Frankenstein’s identity in many ways that unveil its deferred and different significations. Frankenstein’s cinematic sidekicks might well be expressions of his interal duality, insidekicks comparable to those the “hideous progeny” gives in the fertile womb of its mother.
Formation and Longevity of Network Relationship Practices of Ghanaian Traders Importing from China
Authors: Obeng Mark Kweku, Mensah
Published: October 2020

Using qualitative data gathered in Ghana and China from Ghanaian importers of Chinese products, this paper addresses two major gaps in the social network literature: formation and cessation of network relationships. The study adapts social network theory, social exchange theory, and rational choice theory to argue that networks are purposely established when a party desires a result and set objective(s) it lacks the competence to accomplish. That party will procure the services of a competent person, at a cost, in order to achieve the set objective(s). It is argued that besides the lack of personal capacity, opportunity cost also explains the formation of network relationships. Furthermore, subject to the nature and personal characteristics of the object to be obtained and the parties to the formed network, the relationship may turn out to be eithera one-off transaction or couldbecome an enduring exchange relationship.Formation and Longévité de Relations sur les Réseaux Pratiques de marchands ghanéens important des produits de Chine.RésuméEn s’appuyant sur de données qualitatives collectées au Ghana et en Chine auprès des importateurs de produits chinois, cet article fait le point sur deux lacunes principales qui existent dans la littérature sur les réseaux sociaux: la formation et  la rupture de relations sur les réseaux sociaux. Cette étude, à l’aide de la théorie de réseaux sociaux, la théorie d’échange social et la théorie du choix rationnel, tient que les réseaux sont délibérément établis lorsqu’une partie désire obtenir des résultats mais ne possède pas les compétences pour en atteindre les objectifs définis. Ladite partie engagera les services d’une personne compétente, moyennant un prix, afin d’atteindre lesdits objectifs. Il est soutenu qu’outre le manque de capacité personnelle, le coût d’opportunité explique également la formation de relations sur les réseaux sociaux. Par ailleurs, en fonction de la nature et des caractéristiques personnelles de l’objet [de la relation] et des parties au réseau créé, la relation pourrait être soit une seule transaction ou une relation d’échange durable.
Evaluative Speech Acts of Ghanaian Graduate Students: A Case Study of the University of Cape Coast, Ghana
Authors: Bisilki Abraham Kwesi , Bisilki Isaac
Published: October 2020

This paper describes an aspect of language use in the Ghanaian academic community, specifically investigating the use of evaluative speech acts in the review language of graduate students at the University of Cape Coast (UCC). The study is situated in Hyland’s (2004) conceptual framework of evaluative language. Using a content analysis approach to corpora, the study revealed that the reviews of the graduate students contained both positive and negative evaluative speech acts as well as linguistic mitigating strategies meant to soften criticisms that were face-threatening. However, it is worthy of note that the positive speech acts or praises were recorded in a higher proportion than were the criticisms. More intriguing was the discovery that much more of both the praise and the criticism were focused on the text, rather than on the author. Overall, the pattern of evaluative language use discovered in this analysis, if generalisable, renders the academic discourse culture of the Ghanaian graduate student more akin to Asian linguistic cultures than to Western ones.   Actes de Discours Evaluatif des Etudiants de Cycle Supérieur de l’University of Cape Coast, Ghana   Résumé Cet article décrit un aspect de l’utilisation du langage dans la communauté académique ghanéenne, en examinant, notamment, l’utilisation des actes de discours évaluatif dans le langage des étudiants de cycle supérieur de l’University of Cape Coast (UCC). Cette étude se situe dans le cadre théorique conceptuel de Hyland (2004) relatif à l’utilisation du langage évaluatif.  En utilisant une approche pour l’analyse du contenu appliquée au corpus, l’étude a révélé que les évaluations des étudiants de cycle supérieur comprenaient à la fois les actes de discours positif et négatif ainsi que certaines stratégies atténuantes linguistiques adoptées pour adoucir les critiques qui étaient menaçantes pour la face. Toutefois, il est important de noter que les actes de discours positif ou d’éloges étaient enregistrés dans une proportion supérieure à celle des critiques. Il est aussi intéressant de noter que, selon la découverte faite, la plupart des éloges et des critiques étaient concentrés sur le texte, plutôt que sur l’auteur. En général, le schéma d’utilisation du langage découvert dans cette analyse, si généralisable, rend la culture de discours scolaire de l’étudiant ghanéen de cycle supérieur plus comparable aux cultures linguistiques asiatiques qu’à celles de l’Occident.
SPHAERODACTYLUS GRANDISQUAMIS, A VALID SPECIES
Authors: Grant Chapman
Published: October 2020

Resumen en inglés
THE INITIATION OF AN INSECT PEST SURVEY IN PORTO RICO
Authors: Leonard M. D.
Published: October 2020

A brief account of the initiation of periodic observations and reports on the more important and injurious insects in Porto Rico in cooperation with the Insect Pest Survey office of the United States Bureau of Entomology. Faunal studies, both past and present are referred to and methods of collecting and recording Survey data are described. The objects of an Insect Pest Survey and the benefits to be derived from such work, both local and international, are suggested.
THE PINK BOLLWORM OF COTTON IN PORTO RICO
Authors: Leonard M. D.
Published: October 2020

The introduction, spread and present status of the pink bollworm, Pectinophora gossypiella Saunders, in Porto Rico are described. In order to understand the somewhat unusual conditions under which the insect is working in the Island the essential climatic and topographic features and the development of Sea Island cotton growing in Porto Rico are briefly outlined. Attempts at control are discussed together with the relation of alternate host plants as a factor in carry-over of the insect from one crop to another.
NOTES ON THE GENUS ANERISTUS HOWARD WITH DESCRIPTIONS OF NEW SPECIES (Hymenoptera: Chaleidoidea)
Authors: Dozier Herbert L.
Published: October 2020

The purpose of this paper is to establish as clearly as possible the status of the genus Aneristus Howard, to assemble all the available information concerning the habits and host-relationships of its members, and to make known three new species from the West Indies. So far as known all the species of Aneristus are primary parasites of the non-diaspine Coccidae or soft scale insects and are of great economic importance.
THREE SPECIES OF EMPOASCA LEAFHOPPERS KNOWN TO AFFECT ECONOMIC PLANTS IN HAITI (INCLUDING THE DESCRIPTION OF TWO NEW SPECIES)
Authors: DeLong Dwight M.
Published: October 2020

Resumen en inglés
A NEW CITRUS CAMBIUM MINER FROM PUERTO RICO
Authors: Felt E. P.
Published: October 2020

Resumen en inglés
HERPETOLOGICAL NOTES FROM THE PUERTO RICO AREA
Authors: Grant Chapman
Published: October 2020

Resumen en inglés
HERPETOLOGY OF TORTOLA; NOTES ON ANEGADA AND VIRGIN GORDA, BRITISH VIRGIN ISLANDS
Authors: Grant Chapman
Published: October 2020

Resumen en inglés
THE CRANE-FLIES OF PUERTO RICO (Diptera)
Authors: Alexander Charles P.
Published: October 2020

Resumen en inglés
ON THE LIFE-HISTORY AND SYSTEMATIC POSITION OF THE ORGANISMS CAUSING DRY TOP ROT OF SUGAR CANE
Authors: Ivimey Cook W. R.
Published: October 2020

Resumen en inglés
NOTES ON INSECT CONDITIONS IN PUERTO RICO FOR THE FISCAL YEAR, JULY 1931 THRU JUNE 1932
Authors: Leonard Mortimer B.
Published: October 2020

Resumen en inglés.
PUERTO RICO SEEDLESS ORANGE SELECTIONS
Authors: Shamel A. D. , Twight E. H.
Published: October 2020

Resumen en inglés.
THE LIMA BEAN POD-BORER CATERPILLARS OF PUERTO RICO
Authors: Wolcott George N.
Published: October 2020

Resumen en inglés.
THE PRESENT STATUS OF WHITE GRUB PARASITES IN PUERTO RICO
Authors: Wolcott George N.
Published: October 2020

Resumen en inglés.
EFFECT OF BORON ON THE GROWTH OF CERTAIN GREEN PLANTS
Authors: Rodríguez Géigel Antonio
Published: October 2020

1. Under the usual water-culture methods boron proved toxic to Spirodela polyrhyza at concentrations of above 1 p.p.m. Toxicity was evident in reduced growth, smaller plants, and loss of roots. In concentrations above 5 p.p.m. death soon occurred. Chlorosis was noted in all the cultures but those plants with boron were slightly more chlorotic than the controls. In both cases the addition of inorganic iron was without effect, but the addition of potassium tartrate at a concentration of 20 p.p.m. resulted in a marked chlorophyll development in all the cultures. 2. Under pure culture conditions boron seemed to increase growth at certain concentrations. At a concentration of 5 p.p.m. toxicity was apparent. No chlorosis was noted with boron. 3. With Chlorella under pure culture conditions marked stimulation was noted in experiments 6 and 7 with concentrations up to 10 p.p.m. and even with higher concentrations In experiments 8, 9 and 10 no stimulation was noted. 4. Chlorella proved extremely resistant to boron. A concentration of 30 p.p.m. was required to decrease growth on experiment 6 while in experiment 9 toxicity was noted at a concentration of 10 p.p.m. as evidenced by decreased growth, but survived at a concentration of 140 p.p.m. No chlorosis was noted in any case. 5. The addition of sodium citrate or potassium tartrate, both of which tend to increase iron availability did not decrease the toxicity of boron when growth was taken as the criterion. 6. The addition of dextrose to the culture medium increased growth as expected and made Chlorella much more resistant to boron. This was likewise true of sucrose. 7. Boron did not decrease the availability of iron. 8. Boron was not found present in the precipitation formed in the culture medium. The method of analysis used was not very sensitive.
NITRIFICATION STUDIES WITH SOIL TYPES IN NORTHERN PUERTO RICO
Authors: Bonnet Juan Amedee
Published: October 2020

Experimental results have been reported on the nitrification rate of nine soil types from Northern Puerto Rico classified as: Catalina clay, Catalina clay level phase, Coto clay light texture phase, Espinosa clay, Lares clay loam, Mucara silty clay loam, Mucara silt loam, Sabana Seca clay and Toa silt loam. The various soil types are represented by twenty-one different soil samples. Some experimental data is also reported for a soil type from New Jersey classified as Sassafras sandy loam.
HOST INDEX OF VIRUS DISEASES OF PLANTS
Authors: Cook Melville T.
Published: October 2020

Resumen en inglés.
INSECTAE BORINQUENSES
Authors: Wolcott George N.
Published: October 2020

Resumen en inglés.
THE LIFE HISTORY OF "DIAPREPES ABBREVIATUS" L., AT RIO PIEDRAS, PUERTO RICO
Authors: Wolcott George N.
Published: October 2020

1. The females of Diaprepes abbreviatus L. lay 5,000 or more (or less) eggs in as few as two months, May and June, or in as many as seven months at other times of the year, often living over twice as long as do the males after emergence from the soil. 2. The incubation period of all eggs is seven days. Larvae attain full size in two to four months. A diapause period is absolutely essential before pupation. The pupal period is about two weeks. Fully-formed adults remain within the pupal chamber for a variable period of weeks or months, the length of this period and that of the diapause period of the larva being subject to great variation. 3. The great variation in the duration of the diapause period of the larva and before the emergence of the adult from the pupal cell in the ground permits some individuals to complete their life-cycle (hatch ing of eggs to first egg-cluster laid by female, or to emergence of male from soil) in less than eight months, but for other individuals it may extend for eighteen months (hatching of egg to last egg-cluster laid by female, or to death of male). 4. Deviation from a one-year life-cycle is of tremendous value to Diaprepes abbreviatus L. in enabling its eggs to escape attack by a common parasitic wasp, Tetrastichus haitiensis Gahan, which is most abundant during the late spring, but very scarce during autumn and winter.
THE CICADELLIDAE OF CUBA
Authors: Metcalf Z. P.
Published: October 2020

Resumen en inglés.
IMPRESSIONS ABOUT THE COVID-19 PANDEMIC AND BONE MARROW TRANSPLANTATION
Authors: Paton Eduardo
Published: October 2020

Covid-19 pandemic and Bone Marrow Transplantation
OVERVIEW OF THE BRAZILIAN OUTCOMES FROM FIRST MULTICENTRIC STUDY WITH USE FROM DATABASE CIBMTR. A PILOT STUDY.
Authors: Da Silva Cinthya Corrêa , Arcuri Leonardo Javier , Simione Anderson João , Das Neves Heliz Regina Alves , Geraldo Bruna Letícia Da Silva Santos , Vigorito Afonso Celso , Funke Vaneuza Araújo Moreira , Colella Marcos Paulo , Ribeiro Andreza Alice Feitosa , Rocha Vanderson Geraldo , Esteves Iracema , Bonfim Carmem , Zecchin Victor Gottardello , Duarte Fernando Barroso , Da Silva Roberto Luiz , Monteiro Cintia , Lopes Germison Silva , Guzelotto Larissa Codogno , Nabhan Samir , Colturato Vergílio Antonio Rensi , Hamerschlak Nelson
Published: October 2020

To better understand the outcomes of HSCT in Brazil, we conducted a multicenter study using the CIBMTR database. Seven participating centers extracted their own data through the Data Back to Center tool. Main indications for HSCT-auto were MM(51%), NHL(18%) and HL(17%); Allogeneic, AML(24%), ALL(23%) and SAA(15%). For acute leukemias, risk of death was higher in the 18-40 years group (HR=1.18,p=0.022), 40-60(HR=1.19,p<0.001) and 60+(HR=1.39,p=0.007), compared with 0-18 years, in ALL (HR=1.05,p <0.001, compared with AML) and with partially-matched related donor (HR=1.59,p= 0.003, compared with matched sibling), while URD was not. HSCT in CR2+(HR=1.28,p=0.01) and relapse (HR=2.44,p< 0.001) were risk factors for death. 49%(95CI:44-52)52%(95CI:43-62)45%(95CI:39-51) and 55%(95CI:49-63), somewhat poorer than the CIBMTR: 62 and 70%, respectively.  Limited access to novel drugs for most centers and lack of molecular risk information are possible explanations for these differences. Further studies are necessary to better evaluate our findings and the DBtC tool enables multicenter studies.
RECENT ADVANCES IN HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR INHERITED BONE MARROW FAILURE SYNDROMES
Authors: Darrigo Junior Luiz Guilherme , Bomfim Carmem
Published: October 2020

The inherited bone marrow failure syndromes (IBMFS) are a heterogeneous group of genetic disorders characterized by the inadequate production of at least one of the hematopoietic lineages, leading to the development of both isolated cytopenia (anemia, neutropenia, or thrombocytopenia) or pancytopenia. Different biological mechanisms justify the pathophysiological changes found in the IBMFS, emphasizing the repair pathways in Fanconi anemia (FA), maintenance of telomeres in congenital dyskeratosis, and ribosome biogenesis in Shwachman Diamond syndrome (SSD) and Blackfan Diamond anemia. These disorders are generally associated with the presence of congenital malformations and an increased risk of cancer, mainly hematological, gynecological, and head and neck neoplasms. Although the diagnosis occurs typically in childhood, adult patients, mostly below 40 years of age with signs and symptoms suggestive of IBMFS, should be investigated. Currently, hematopoietic stem cell transplantation (HSCT) is the only curative option for hematological complications related to IBMFS.  It is essential to highlight that these patients must be monitored throughout their lives to prevent or detect early treatable neoplasia.
Microethics In Clinical Practice
Authors: Dr. Sandeep S. Kadu  , Ms. Akshaya  Bhaskaran
Published: October 2020

Ethics is defined as moral philosophy or code of morals practiced by a person or group of people.When the term 'ethics' is considered in clinical practice or medical education one tends to think only about the long established ethics like biomedical ethics, research ethics etc. but there are more.
Challenges in the Anaesthetic Management of Congenital Diaphragmatic Hernia in a Tertiary Care Hospital.
Authors: Pol Dr. Milind , Jadhav Dr. Harish , Mhaske Dr. Sunil Natha
Published: October 2020

Introduction: Congenital diaphragmatic hernias (CDH) are complex developmental anomaly. It results from anomalous closure of pericardio-peritoneal canal. Consequently, abdominal organs extrude into the thoracic cavity, impairing the growth of the ipsilateral lung. Surgical correction is the only treatment modality. There are various challenges faced by anesthesiologists such as hypoxia and hypercarbia leading to pulmonary hypertension and right to left shunt. This study is carried out to present perioperative complications that we faced during the anaesthetic management of CDH in patients who underwent surgical closure of the diaphragmatic defect in a tertiary care centre. Method: This is a retrospective study carried over a period of one year. We reviewed the medical records of children with the diagnosis of CDH who underwent surgical correction of diaphragmatic defect. The perioperative complications were recorded as the appearance of bradycardia, hypoxia, sepsis, DIC, pneumothorax and the collected data were analyzed. Result:  Thirteen children presented to the hospital with the diagnosis of CDH and underwent surgical repair. Among them, 9 (69.23%) were male and 4 (30.76%) were female. Hospital presentation on 8 to 30 days of life was noted in 46.15% of the cases, The most common complication during the perioperative period was hypoxia, bradycardia and pneumothorax. The survival rate was 61.53%. Conclusion:  The anaesthetic management of CDH is still a difficult and challenging for anaesthesiologist. Bradycardia, hypoxia, pneumothorax, septicemia and DIC are the major causes of perioperative morbidity and mortality. Preoperative optimization and gentle ventilation strategy makes significant impact on survival in child.
Competencias digitales en el proceso de enseñanza-aprendizaje del docente y estudiante
Authors: Alvarado Rodas Herminia Rosaura
Published: October 2020

Las instituciones educativas afrontan cambios y desafíos en desarrollo y formación tecnológica, con mayor exigencia ocurre en la universidad siendo necesario acreditar al profesor y estudiante para responder a una sociedad llena de incertidumbre. El presente artículo aborda el análisis de las competencias digitales en la enseñanza-aprendizaje previo a la pandemia del COVID-19. El objetivo del estudio es analizar la situación actual respecto al conocimiento, uso y formación en competencias digitales en el proceso de enseñanza-aprendizaje del estudiante y docente del Área Común de la Facultad de Ciencias Económicas. Es un estudio con enfoque cuantitativo, diseño no experimental y alcance descriptivo. Para el cálculo de la muestra se utilizó la fórmula estadística para poblaciones finitas, obteniendo una muestra de 137 estudiantes y 17 docentes. Se realizo una encuesta, el cuestionario se estructuró con 15 preguntas. Los resultados muestran que existe mucho conocimiento de las TIC en los docentes, prevaleciendo a los estudiantes. Se refleja poco uso y aplicación de las TIC en el diseño y ejecución de las actividades académicas. Se muestra poca actualización y formación tecnológica, reflejado con un 71% y 63% en docentes y estudiantes respectivamente. La educación superior requiere el desarrollo de competencias digitales durante la formación de profesionales para alcanzar un mejor desempeño y alta competitividad, en el ámbito personal, laboral y profesional, por ello es preciso que la Facultad de Ciencias Económicas haga frente a nuevos escenarios de aprendizaje.
Departamento de Educación Virtual de Fahusac, Usac, antes de la emergencia sanitaria Covid 19
Authors: Cardona Monroy María Iliana
Published: October 2020

La Facultad de Humanidades desde la plataforma desarrolla actividades del sector administrativo que contribuye a que los procesos académicos, desde inscripción, asignaciones por parte de los estudiantes de diferentes carreras que se suman a la Facultad, puedan llevar su registro histórico estudiantil, en los diferentes cursos de la malla curricular. Las asignaciones de los cursos por parte de los estudiantes generan el acto donde el profesor distribuye la zona que acumula el estudiante, en el desarrollo curricular bajo tres ejes que son docencia, investigación y extensión. Los procesos administrativos son un servicio para el estudiante que permite desarrollar competencias en el uso de las plataformas de la Facultad, tanto a profesores como a estudiantes.  En el ámbito docente en la Facultad se usa la plataforma para desarrollar cursos virtuales, no solo las competencias específicas del Departamento de Educación Virtual, sino que, para desarrollar los cursos de las diferentes carreras pueden solicitar que le abran el curso al encargado de la plataforma. En un acercamiento a la tecnología como recurso didáctico.  En relación a los cursos, se da tutorías presenciales o tutorías virtuales lo que permite lograr excelencia académica y aprendizaje autónomo porque el profesor con la tutoría facilita que todos los estudiantes alcancen las competencias necesarias según los diseños curriculares de las diferentes carreras.
STARTING UP AND REGULATING THE ROTATIONAL SPEED
OF A POWERFUL ELECTRIC DRIVE USING A MAGNETIC REDUCING GEAR
Authors: Afanasyev Alexander A.
Published: October 2020

The article examines a magnetic reducing gear, the stator winding of which receives power in the mode of a valve machine. In the absence of this supply, the electric motor can be started-up in no-load mode. To significantly reduce the power of the magnetic reducing gear frequency converter compared to the power of the adjustable electric motor, it is necessary to make the number of the rotor's pairs of poles with permanent magnets of a magnetic reducing gear large enough. In this case, the design of arranging the magnets in radial grooves is the most adequate, ensuring the concentration of fluxes per pole in the air gaps. The stator winding of such a magnetic reducing gear will be low-pole. When manufacturing a magnetic reducing gear, it is possible to use a stator magnetic core of a serial asynchronous machine together with its regular winding. The electromagnetic moments of the magnetic gearbox rotors are a consequence of the presence of a stator electromagnetic moment. The stator's current frequency is represented by two components, of which the first is defined from the state equations and the second is a constant forming an additional channel of functional influence. The speed of rotation of the gear shafts can be adjusted by changing the specified constant and the input voltage of the frequency converter. The equations of the magnetic reducer state describing its functional modes were solved by means of the Mathcad mathematical program.
EFECTO ANTIFÚNGICO in vitro DE EXTRACTOS METANÓLICOS DE Capsicum spp. EN Moniliophthora roreri
Authors: De la Cruz-Ricardez Dario , Ortiz-García Carlos F. , Lagunes-Espinoza Luz del C. , Torres-de la Cruz Magdiel
Published: October 2020

Uno de los principales problemas fitosanitarios en la producción de cacao (Theobroma cacao L.) en Latinoamérica y en México es la moniliasis, causada por Moniliophthora roreri. Este fitopatógeno causa más del 75% de pérdidas en la producción anual. Los metabolitos secundarios del género Capsicum tienen efectos antifúngicos, por lo que se pueden usar para el control de M. roreri. El objetivo de este experimento fue evaluar el efecto in vitro de extractos metanólicos (EM) de tres especies de Capsicum sobre M. roreri. Los EM extraídos de frutos inmaduros de C. chinense, C. frutescens, y dos morfotipos de C. annuum var. glabriusculum se probaron a dos concentraciones: 1000 y 2500 mg L-1, y se evaluaron en la inhibición del crecimiento micelial, la esporulación y la viabilidad de conidios producidos de M. roreri. Ambas dosis (tratamientos) se establecieron bajo un diseño experimental completamente al azar con cinco repeticiones; cada caja de Petri fue una unidad experimental, los datos se analizaron con ANDEVA y las medias se compararon con la prueba de Tukey (p≤0.05). Moniliophthora roreri fue sensible a los EM de las tres especies. Los EM de C. annuum var. glabriusculum en sus morfotipos amashito (AM) y garbanzo (GA) a 2500 mg L-1 inhibieron el crecimiento micelial hasta en 95%. Los EM de C. annuum var. glabriusculum AM y GA a 2500 mg L-1 inhibieron totalmente la producción de conidios en ambas concentraciones. Los EM de C. chinense y C. annuum var. glabriusculum GA inhibieron hasta 35% la viabilidad de conidios de M. roreri. La sensibilidad in vitro de M. roreri a EM de C. annuum var. glabriusculum AM y GA permite sugerir el efecto de los extractos en el campo de cultivo.
Legislación e instrumentos de manejo existentes para la protección de los fondos marinos en la Plataforma Continental Argentina
Authors: Gaitan Esteban
Published: October 2020

Se presenta un compendio de instrumentos vinculantes y no vinculantes referidos al manejo y protección de los fondos marinos y/o de los invertebrados bentónicos de la Plataforma Continental Argentina (PCA). Se analizaron leyes nacionales y acuerdos internacionales en los cuales Argentina es signataria, así como declaraciones de FAO que establecen principios y normas aplicables a la conservación, ordenación y desarrollo de las pesquerías y ecosistemas asociados. En base a esta selección bibliográfica se analizó la evolución de las medidas a lo largo del tiempo en función del contexto internacional, a fin de esclarecer cuáles son los faltantes y los logros obtenidos en este proceso. Se concluye que Argentina avanzó en la generación de políticas acordes a los lineamientos mundiales que implican un manejo ecosistémico y un mayor resguardo de la biodiversidad, por ejemplo, implementando Áreas Marinas Protegidas, así como con el enunciado de planes de investigación y fomento que involucran el estudio de los fondos marino. Sin embargo, para algunas medidas su efectiva ejecución es parcial a partir de la falta de reglamentación y/o financiamiento. Asimismo, queda pendiente la elaboración de planes de acción concretos referidos al estudio del lecho marino incluido en los nuevos límites exteriores de la PCA.
Dva mimořádné hroby z laténského pohřebiště v Rousínově
Authors: Čižmář Ivan , Mikulková Blanka , Kmošek Matěj , Chovanec Michal , Kala Jiří
Published: October 2020

Development-led excavation in Rousínov in 2017 uncovered a La Tène cemetery in which 30 graves were excavated. Out of these, two exceptional graves, a rich female inhumation and a warrior’s cremation grave, are discussed in detail in this paper. In addition to typological determination of artefacts, the paper includes the results of a survey and conservation work on metal artefacts and anthropological analysis. The inhumation burial of a gracile woman at the age of about 30 years (H823) contained, among other things, a complete bimetallic chain-belt; its furnishing can be dated to LT B2/C1. The warrior’s
cremation contained, among other things, an undeformed sword in its scabbard and a spear-head with an exceptionally decorated socket; the grave goods date to LT C1.