bluuebunny/crossref_metadata_2025 huggingface dataset:
Luminescent lanthanide metallopeptides for biomolecule sensing and cellular imaging
Authors: Sánchez-Fernández Rosalía , Obregon-Gomez Ines , Sarmiento Axel , Vázquez M. Eugenio , Pazos Elena
Published: September 2024

Lanthanide ions display unique luminescent properties, such as long-lived excited states and relatively narrow emission bands, that make them particularly attractive for the development of bioprobes in combination with peptides.
Asymmetric electrophilic functionalization of amino-substituted heteroaromatic compounds: a convenient tool for the enantioselective synthesis of nitrogen heterocycles
Authors: Blay Gonzalo , Monleón Alicia , Montesinos-Magraner Marc , Sanz-Marco Amparo , Vila Carlos
Published: September 2024

The catalytic asymmetric electrophilic functionalization of the less reactive N-heteroaromatic compounds has been reported using the approach of the introduction of an exocyclic amino substituent.
Photoswitchable TCB-2 for control of the 5-HT2A receptor and analysis of biased agonism
Authors: Esmaeili Alireza Jafar , Montazeri Pantea , Gomez Jasmine Cristina , Dumervil Didier J. , Nezhad Faezeh Safar , Steinhardt Rachel C.
Published: September 2024

Therapies that target the serotonin 2A receptor (5-HT2AR) are promising. However, probes are needed to better understand the role of 5-HT2AR.
Eu(iii)-doped calcium molybdate nano- and microstructures: microfluidic synthesis and morphology tuning via solvent dielectric constant and viscosity control
Authors: Ostellari Pietro , Tajoli Francesca , Fortunati Ilaria , Carofiglio Tommaso , Badocco Denis , Pastore Paolo , Gross Silvia
Published: September 2024

Microfluidic synthesis of Eu(iii)-doped calcium molybdate structures: by changing the reaction conditions (solvent mixtures, temperature and quenching), particles with different sizes, size distributions and tunable optical properties were obtained.
Detonation performance and shock sensitivity of energetic material NTO with embedded small molecules: a deep neural network potential accelerated molecular dynamics study
Authors: Wang Caimu , Zhang Jidong , Guo Wei , Liu Ruibin , Yao Yugui
Published: September 2024

Accurate description of detonation performance for explosives remains a challenge for current experimental and theoretical methodologies.
Theoretical screening of the metal-nonmetal pair anchored on N-doped graphene for the oxygen reduction reaction
Authors: Zhang Ji , Zhang Peng , Yu Aimin , Li Dong-sheng , Sun Chenghua
Published: September 2024

The SIr@N8 catalyst composed of S and Ir pair anchored N-doped graphene was picked out by three-step screening strategy, which was identified to exhibit an excellent ORR catalytic performance.
γ-Stearolactone ring-opening by zeolites for the production of branched saturated fatty acids
Authors: Bos Jelle W. , Vloedgraven Job G. A. , Wiedemann Sophie C. C. , van Dongen Leo , Moonen Roel C. J. , Wels Bas , Berben Peter H. , Reesink Bennie H. , de Peinder Peter , Vogt Eelco T. C. , Weckhuysen Bert M.
Published: September 2024

Improvement in γ-stearolactone ring-opening activity of beta zeolites by a favourable change in Brønsted to Lewis acid site ratio, induced by steaming and acid leaching.
Redox properties of [Cp*Rh] complexes supported by mono-substituted 2,2′-bipyridyl ligands
Authors: Stiel Jonah P. , Henke Wade C. , Moore William N. G. , Barker Nathaniel M. , Oliver Allen G. , Day Victor W. , Blakemore James D.
Published: September 2024

Mono-substituted 2,2′-bipyridyl ligands have been demonstrated to afford unique redox properties when incorporated into [Cp*Rh] complexes.
Gradual spin crossover behavior encompasing room temperature in an iron(ii) complex based on a heteroscorpionate ligand
Authors: Horniichuk Oleksandr Ye. , Vendier Laure , Salmon Lionel , Bousseksou Azzedine
Published: September 2024

A series of triazole-based heteroscorpionate ligands synthesized based on heterocycle metathesis reactions and their iron(ii) complexes presenting interesting spin crossover properties around room temperature are reported.
A multi-stimuli–response metal–organic framework nanopesticide for smart weed control in agriculture
Authors: Zhang Dingyang , Guo Xueping , Rao Wenhua , Pan Danmei , Cao Fang , Zhai Tianyun , Zheng Wenhui , Abubakar Yakubu Saddeeq , Guan Xiong , Chen Zhi , Pan Xiaohong
Published: September 2024

Herbicides play an important role in weed control when it comes to ensuring a high and consistent yield in agriculture, but their effectiveness is often compromised by climatic variables.
Ultraviolet radiation restrains marine biofouling during uranium extraction from seawater
Authors: Yan Meng , Gao Qianhong , Shao Dadong
Published: September 2024

Marine biofouling, which is related to the survival and reproduction of marine microorganisms, seriously limits uranium (U(vi)) extraction from seawater.
Enhancement of the flavor and functional characteristics of cod protein isolate using an enzyme–microbe system
Authors: Yan Zheng-Fei , Chen Jia-Yu , Yang Jing , Yuan Shuai , Qiao Xue-Yi , Xu Bo , Su Ling-Qia
Published: September 2024

Cod protein isolate was first debittered using Streptomyces canus aminopeptidase (ScAPase) and then deodorized through probiotic fermentation, showing the most substantial. These products showed the most substantial proliferation effect on probiotics.
Unlocking the potential of methionine: a dietary supplement for preventing colitis
Authors: Wang Hui-Li , He Yang , Wang Song-Wei-Min , Aziz-ur-Rahman Muhammad , Zhang Si-Yu , Shi Chang-Xiao , Wang Hao-Ming , Su Hua-Wei
Published: September 2024

Mechanism modelling of methionine supplementation shows that it triggers antioxidant, anti-inflammatory, and barrier-protective responses, increases SCFA production, and alleviates colitis.
Heat shock cognate 70 protein is a novel target of nobiletin and its colonic metabolites in inhibiting colon carcinogenesis
Authors: Gao Zili , Zheng Jinkai , Wu Xian , Savinov Sergey , Zhao Chengying , Xiao Hang
Published: September 2024

HSC70 has been identified as a direct protein target of nobiletin (NBT), and the interaction between NBT and HSC70 triggers cancer cell death.
Trace element determination by femtosecond LA-ICP-MS in 10 mg extraterrestrial geological samples prepared as lithium borate glasses
Authors: Liu Yan-Hong , Xue Ding-Shuai , Li Wen-Jun , Wang Zhong-Qiang , Liang Yan , Guo Shun , Wan Bo
Published: September 2024

This method involves precise trace element determination in X-ray fluorescence (XRF) lithium borate glass prepared from 10 mg extraterrestrial geological samples using femtosecond LA-ICP-MS.
A new way to improve the fire safety of polyurethane composites with the assistance of metal–organic frameworks
Authors: Hu Jinhu , Pan Ye-Tang , Zhou Keqing , Song Pingan , Yang Rongjie
Published: September 2024

Polyurethane (PU) is extensively utilized for its outstanding properties.
Microneedle (MN)-based sensing technology: an innovative solution for agriculture
Authors: Kumari Sonu , Talreja Neetu , Chauhan Divya , Ashfaq Mohammad
Published: September 2024

Agricultural health is one of the most important aspects of improving crop productivity, which can significantly decrease demand for food. MN-based sensing technology offers newer insight into agriculture health by continuously monitoring plant health, including nutritional values and pathogens.
Atypical breathing driven two-dimensional valley multiferroicity
Authors: Feng Yangyang , Zhao Jiangyu , Dai Ying , Huang Baibiao , Ma Yandong
Published: September 2024

A novel mechanism of coupling ferro-valleytricity with ferroelectricity, i.e., single-phase valley multiferroicity, in a two-dimensional magnetic lattice.
Doxorubicin and iron-doped mesoporous silica nanoparticles for chemodynamic therapy and chemotherapy of breast cancer
Authors: Tang Le , Chen Mingjian , Wang Dan , He Yi , Ge Guili , Zeng Zhaoyang , Shu Jinyong , Guo Wenjia , Wu Steven Xu , Xiong Wei
Published: September 2024

This study depicts a simple and effective strategy for designing an intelligent drug delivery system activated by the tumor-specific weakly acidic microenvironment, offering a promising biotechnological platform for combined breast cancer treatment.
Spontaneous formation of monocrystalline nanostripes in the molecular beam epitaxy of antimony triselenide
Authors: Wojnar Piotr , Chusnutdinow Sergej , Kaleta Anna , Aleszkiewicz Marta , Kret Slawomir , Domagala Jaroslaw Z. , Ciepielewski Pawel , Yatskiv Roman , Tiagulskyi Stanislav , Suffczyński Jan , Suchocki Andrzej , Wojtowicz Tomasz
Published: September 2024

Self-assembled, highly anisotropic nanostructures are spontaneously formed in the molecular beam epitaxy of antimony triselenide on GaAs substrates.
Synthesis and properties of phosphorus nanostructures on Au(110)
Authors: Zhang Xiao , El kari Hamza , Enriquez Hanna , Bendounan Azzedine , Kara Abdelkader , Dappe Yannick J. , Oughaddou Hamid
Published: September 2024

Phosphorus nanostructures are synthesized on an Au(110) substrate via molecular beam epitaxy. We obtain self-assembled phosphorus dimers at low coverage and long-range phosphorus nanoribbons at higher coverage. Both present metallic character.
Coalescence-induced shape transformations in Pd and AuPd clusters
Authors: Nelli Diana , Dighero Edoardo , Ferrando Riccardo
Published: September 2024

The final structures after the collision of icosahedral nanoparticles with fcc ones depend on composition. Icosahedral final structures are obtained when colliding AuPd clusters, while collisions of pure Pd clusters leads to fcc structures.
A facile and versatile platform for preparing uniform π-conjugated nanofibers with controlled length and varying shells
Authors: Xiang Bo , Wu Hongluo , Chen Rang , Huang Xiaoyu , Lu Guolin , Feng Chun
Published: September 2024

A versatile and facile platform is developed for the generation of uniform π-conjugated nanofibers with controlled length and varying shells by the combination of pentafluorophenyl ester chemistry and a self-seeding strategy.
Rationally reconstructing the surface microstructure of a chemical bath deposited electron transport layer for efficient and stable perovskite solar cells
Authors: Yang Xinxuan , Wang Lexin , Liu Meihan , Jin Jiahui , Yang Lili , Fan Lin , Wei Maobin , Liu Huilian , Chen Haoran , Yang Jinghai , Chang Yulei , Wang Fengyou
Published: September 2024

A reconstruction strategy is designed to manipulate the surface microstructure of a CBD SnO2 ETL, yielding PSCs with a high PCE >24%.
A high-entropy FeCoMnCuNi diselenide self-standing electrode with outstanding water-electrolysis performance in alkaline medium
Authors: Guo Xinxin , Zhou Mengmeng , Liu Ziwu , Mu Shiheng , Wang Kaijia , Shi Huanqiang , Wang Fang , Lu Shijian , Ni Zhonghai , Liu Guiqing
Published: September 2024

A self-standing high-entropy FeCoMnCuNiSe2 electrode exhibited superior HER activity and OWS performance due to high entropy, lattice distortion and tip-enhancement effects.
Synergistic Fe,Ce doping of Ni3S2 for enhancing oxygen evolution reaction performance
Authors: He Yu , Shi Kefan , Wang Xueqin , Zheng Xingzi , Luo Lanke , Lin Liu , Sun Zemin , Sun Genban
Published: September 2024

Fe,Ce-Ni3S2@NF nanoneedle catalysts synthesised via a one-step hydrothermal route showed good OER performance.
Recent advances in cooperative N-heterocyclic carbenes and photocatalysis
Authors: Tian Kui , Xia Zi-Fei , Wei Jun , Tao Hai-Yan , Dong Xiu-Qin
Published: September 2024

Combination of N-heterocyclic carbene catalysis and photocatalysis with radical process is a powerful strategy to access useful molecules. In this review, we summarized recent advances in this growing area from the perspective of reaction mechanism.
Transition-metal-catalyzed C–Ge coupling reactions
Authors: Ke Jie , Chen Cadmus Du , Ren Li-Qing , Zu Bing , Li Bin , He Chuan
Published: September 2024

This review covers the development and recent progress in transition-metal-catalyzed C–Ge coupling reactions. The goal is to provide a clear overview of the field, identify current challenges, and inspire further applications in this growing area.
NSAIDs between past and present; a long journey towards an ideal COX-2 inhibitor lead
Authors: Khalil Nadia A. , Ahmed Eman M. , Tharwat Toka , Mahmoud Zeinab
Published: September 2024

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most abundantly used classes among therapeutic agents in medicine.
Direct photochemical intramolecular [4 + 2] cycloadditions of dehydrosecodine-type substrates for the synthesis of the iboga-type scaffold and divergent [2 + 2] cycloadditions employing micro-flow system
Authors: Tay Gavin , Nishimura Soushi , Oguri Hiroki
Published: September 2024

Photocyclisation reactions offer a convenient and versatile method for constructing complex polycyclic scaffolds, particularly in the synthesis of natural products.
Precision-engineered metal–organic frameworks: fine-tuning reverse topological structure prediction and design
Authors: Wu Xiaoyu , Jiang Jianwen
Published: September 2024

A fine-tuned reverse topological approach is developed for structure prediction and 94 823 precision-engineered metal–organic frameworks are designed.
Simplifying complexity: integrating color science for predictable full-color and on-demand persistent luminescence using industrial disperse dyes
Authors: Xiao Guowei , Wang Xiaoyan , Fang Xiaoyu , Du Jinmei , Jiang Yang , Miao Dagang , Yan Dongpeng , Xu Changhai
Published: September 2024

This work leverages subtractive color mixing calculations on disperse dyes to achieve an on-demand design strategy for constructing full-color afterglow with high prediction accuracy (88.89%).
The fluctuation–dissipation relation holds for a macroscopic tracer in an active bath
Authors: Boriskovsky Dima , Lindner Benjamin , Roichman Yael
Published: September 2024

We experimentally determine the conditions under which a fluctuation-dissipation relation holds for a tracer particle in an active bath of self-propelled walkers, yielding an effective temperature that coincides with the particle’s potential energy.
Effects of hydrothermal etching and conversion on photocatalytic hydrogen evolution and overall water splitting with nanoparticulate and mesoporous TiO2 and SrTiO3/TiO2 composites
Authors: Schumacher Lion , Timm Jana , Marschall Roland
Published: September 2024

Hydrothermal treatment of mesoporous photocatalysts in diluted NaOH solution or H2O might be a simple and promising strategy to improve photocatalytic activities in general, as we show for TiO2 and SrTiO3/TiO2 composites.
Effects and mechanisms of berberine-loaded tetrahedral framework nucleic acids on osteoporosis
Authors: Zhang Weifei , Guo Chuan , Yao Dengbo , Lan Weiqiang , Zhou Mi , Huang Zhangheng , Kong Qingquan
Published: September 2024

A new nanocomplex T-BBR was synthesized by carrying BBR with tFNAs. Compared with BBR, T-BBR showed better osteogenic and anti-osteoporosis abilities in both in vivo and in vitro experiments through the Wnt/β-catenin signaling pathway.
Design strategies of rare-earth luminescent complexes with zero thermal quenching protected by the wire-in-tube structure and the construction of a W-WLED with highly stable illumination and colour reproduction
Authors: Ma Yunxiao , Li Ya , Yu Hui , Lv Zhijia , Guan Xin , Yu Jiabao , Ma Shuang , Xia Long , Dong Xiangting
Published: September 2024

TbSSA@ZnO/SnO2 with a wire-in-tube structure is constructed. ZnO/SnO2 shell effectively protects TbSSA core to resist the high operating temperature of 200 °C. The prepared W-WLEDs can maintain stable illumination under floating driving currents.
Heavy metal-free colloidal quantum dots: preparation and application in infrared photodetectors
Authors: Zhang Xuegang , Mu Ge , Zhang Yongzhe , Jiang Yijian , Yan Yinzhou
Published: September 2024

Heavy metal-free colloidal quantum dots (CQDs) are ideal materials for overcoming heavy metal problems. In this paper, the synthesis progress of CQDs and their phased research progress in the field of multi-type infrared detection are reviewed.
AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure
Authors: Vanni Ettore , Beauloye Christophe , Horman Sandrine , Bertrand Luc
Published: September 2024

Heart failure (HF) represents a multifaceted clinical syndrome characterized by the heart’s inability to pump blood efficiently to meet the body’s metabolic demands. Despite advances in medical management, HF remains a major cause of morbidity and mortality worldwide. In recent years, considerable attention has been directed toward understanding the molecular mechanisms underlying HF pathogenesis, with a particular focus on the role of AMP-activated protein kinase (AMPK) and protein O-GlcNAcylation. This review comprehensively examines the current understanding of AMPK and O-GlcNAcylation signalling pathways in HF, emphasizing their interplay and dysregulation. We delve into the intricate molecular mechanisms by which AMPK and O-GlcNAcylation contribute to cardiac energetics, metabolism, and remodelling, highlighting recent preclinical and clinical studies that have explored novel therapeutic interventions targeting these pathways.
Floating Ball Voice Therapy: Preliminary Effects on Outcomes and Predicting Individual Patient Differences in Generalization
Authors: Van Stan Jarrad H. , Hillman Robert E. , Krusemark Carol , Muise Jason , Stadelman-Cohen Tara , Mehta Daryush D. , Sternad Dagmar
Published: September 2024

Purpose:

Floating ball voice therapy (FBVT) is a voice-controlled virtual environment based on a common treatment component across multiple evidence-based therapies: improved vocal efficiency (target) via practicing voicing with modified resonance and airflow (ingredient). This study preliminarily tested FBVT's effects on outcomes and the potential for its novel variability metrics to predict individual patient generalization.

Method:

Ten patients with nonphonotraumatic vocal hyperfunction (NPVH) practiced FBVT for 10 days. Outcomes were assessed by a vocal efficiency ratio, a validated NPVH index, the patient-reported Voice-Related Quality of Life (V-RQOL), and forced-choice auditory judgments of overall severity. Exploration in early practice (Day 1) was estimated by how the patient's two-dimensional variability (mean airflow and intensity) related to error (difference between the patient-produced and normative vocal efficiency ratio). Generalization from the game to spontaneous speech was evaluated using the validated NPVH index.

Results:

Ten days of FBVT were associated with improved vocal efficiency (Cohen's
d
= 1.3), NPVH index (
d
= −1.1), V-RQOL total score (
d
= 0.9), and overall severity (odds ratio = 2.5). Patients who generalized on Day 10 exhibited airflow/intensity exploration that was more aligned with the error gradient on Day 1 (
d
= 0.6–1.2).

Conclusions:

A relatively small dosage of FBVT (i.e., 10 practice sessions) was associated with multiple improved voice therapy outcomes. The FBVT variability metrics on Practice Day 1 demonstrated strong potential to predict which patients generalized to connected speech. Future work can more thoroughly evaluate effects on outcomes and characterizing the quality of vocal exploration with a larger patient population.

Supplemental Material:

https://doi.org/10.23641/asha.27040873
Secure data sharing technology of medical privacy data in the Web 3.0
Authors: Guo Shusheng , Chen Cheng , Tong Qing
Published: September 2024

The development of Web 3.0 technology may signify the dawn of a new digital era. Its concepts of co‐management, co‐construction, and sharing address the need for private data sharing among medical institutions. However, the sharing of private data has been challenging due to the lack of effective monitoring methods and authorization mechanisms. Additionally, controlling the scope of data sharing, providing incentives, and ensuring legal compliance have presented difficulties. To this end, a medical privacy data security sharing model based on key technologies of Web 3.0 has been proposed and implemented. It stores the source data in Inter Planetary File System by constructing an index of private data keywords, generates trapdoors using query keywords, and achieves retrieval of ciphertext data. Finally, data users apply to multiple parties for joint secure computing to obtain the use of private data. The experimental results indicate that when the size of the private data is less than 5 MB, with 3000 ciphertext indexes and three search keywords, both encryption and decryption times are around 50 ms, and the retrieval time is approximately 1.6 s. This performance is adequate for typical medical privacy sharing and computing scenarios.
MultiJSQ: Direct joint segmentation and quantification of left ventricle with deep multitask‐derived regression network
Authors: Du Xiuquan , Pei Zheng , Liu Ying , Cao Xinzhi , Li Lei , Li Shuo
Published: September 2024

Quantitative analysis of clinical function parameters from MRI images is crucial for diagnosing and assessing cardiovascular disease. However, the manual calculation of these parameters is challenging due to the high variability among patients and the time‐consuming nature of the process. In this study, the authors introduce a framework named MultiJSQ, comprising the feature presentation network (FRN) and the indicator prediction network (IEN), which is designed for simultaneous joint segmentation and quantification. The FRN is tailored for representing global image features, facilitating the direct acquisition of left ventricle (LV) contour images through pixel classification. Additionally, the IEN incorporates specifically designed modules to extract relevant clinical indices. The authors’ method considers the interdependence of different tasks, demonstrating the validity of these relationships and yielding favourable results. Through extensive experiments on cardiac MR images from 145 patients, MultiJSQ achieves impressive outcomes, with low mean absolute errors of 124 mm2, 1.72 mm, and 1.21 mm for areas, dimensions, and regional wall thicknesses, respectively, along with a Dice metric score of 0.908. The experimental findings underscore the excellent performance of our framework in LV segmentation and quantification, highlighting its promising clinical application prospects.
Dynamic and efficient device collaborations in 5G‐advanced and 6G networks
Authors: Han Xianghui , Zhou Shuai , Kou Shuaihua , Li Jian , Liu Ruiqi , Jin Shi
Published: September 2024

Collaborative transmission, comprising multiple devices owned by a single user, is progressively evolving into an essential strategy to meet the stringent demands of burgeoning collaborative scenarios in 5G‐advanced and 6G networks. This paper proposes three novel use cases for device collaboration, namely data duplication, data splitting and wireless backup, to address these requirements. To provide dynamic and efficient collaboration, both non‐transparent mode via the medium access control layer collaboration and transparent mode via the physical layer collaboration are proposed. The paper further introduces a comprehensive design framework including protocol stack design, user equipment capability reporting, user equipment pairing, scheduling mechanism and transmission mechanism for different collaborative use cases with different collaborative modes. Evaluation outcomes reveal that the recommended methods could decrease the resources consumed for data duplication while increasing the user perceived throughput for data duplication and data splitting. The proposed methods also augment transmission reliability for both data duplication and wireless backup.
Leveraging modality‐specific and shared features for RGB‐T salient object detection
Authors: Wang Shuo , Yang Gang , Xu Qiqi , Dai Xun
Published: September 2024

Most of the existing RGB‐T salient object detection methods are usually based on dual‐stream encoding single‐stream decoding network architecture. These models always rely on the quality of fusion features, which often focus on modality‐shared features and overlook modality‐specific features, thus failing to fully utilise the rich information contained in multi‐modality data. To this end, a modality separate tri‐stream net (MSTNet), which consists of a tri‐stream encoding (TSE) structure and a tri‐stream decoding (TSD) structure is proposed. The TSE explicitly separates and extracts the modality‐shared and modality‐specific features to improve the utilisation of multi‐modality data. In addition, based on the hybrid‐attention and cross‐attention mechanism, we design an enhanced complementary fusion module (ECF), which fully considers the complementarity between the features to be fused and realises high‐quality feature fusion. Furthermore, in TSD, the quality of uni‐modality features is ensured under the constraint of supervision. Finally, to make full use of the rich multi‐level and multi‐scale decoding features contained in TSD, the authors design the adaptive multi‐scale decoding module and the multi‐stream feature aggregation module to improve the decoding capability. Extensive experiments on three public datasets show that the MSTNet outperforms 14 state‐of‐the‐art methods, demonstrating that this method can extract and utilise the multi‐modality information more adequately and extract more complete and rich features, thus improving the model's performance. The code will be released at https://github.com/JOOOOKII/MSTNet.
A simulation algorithm for SAR echoes with targets in non‐uniform backgrounds
Authors: Song Zhiyong , Zhang Yongqiang , Lan Chujun
Published: September 2024

This article introduces a high‐precision SAR echo simulation method aimed at providing a large‐scale SAR echo simulation algorithm that includes complex target information. This method independently simulates targets and ground clutter, calculating the shadow areas of targets and the dihedral effects between targets and the ground by constructing virtual rough surfaces and using ray tracing. Furthermore, this method can provide data sources for algorithms that improve detector performance using shadow or specular reflection characteristics. Finally, after comparing the simulation results with the publicly available MSTAR dataset, the experimental results show that this method ensures the accuracy of the results. This research provides a rich data source for the study of SAR detection and tracking algorithms and offers strong support for practical applications.
A high‐performance asynchronous readout circuit with cascade function for a neural recording micro‐electrode array
Authors: Feng Jiaqi , Cai Yujie , Huang Leilei
Published: September 2024

The data‐driven machine learning technology used for neural decoding emphasizes the requirements of in vivo and in vitro neural signal acquisition with high spatial and temporal resolution. However, micro‐electrode arrays (MEAs) that simultaneously achieve high spatial and temporal resolution neural signal acquisition are not yet available. Meanwhile, the high data bandwidth of large‐scale MEA brings challenges in power consumption, data transmission, storage, and neural signal processing. This research aims to improve the spatial and temporal resolution of MEA, reduce the cost and time of large‐scale MEA customization through cascading, and reduce the bandwidth of large‐scale MEA through spike compression. Firstly, based on in‐pixel spike detection, a row‐based neural spike readout mechanism and related array circuit to improve the neural spike readout performance and temporal resolution of neural signal acquisition is proposed. To further enhance the spatial resolution and reduce the risk of large‐scale MEA fabrication, the cascading capability of the readout circuit is explored. Lastly, spatial correlation‐based neural spike encoding is proposed to reduce the data bandwidth, achieving a 5.2× compression rate. This is a study on implementing large‐scale MEA through cascaded readout circuits and novel study to utilize the spatial correlation between detected neural spikes for further compression.
Optimised design of electric actuators for more electric aircraft considering machining and assembly errors
Authors: Li Wenlong , Wu Qingle , Yang Guolai , Guo Chengyuan
Published: September 2024

To the challenges posed by the complex structure and low reliability of existing hydraulic actuators used for more electric aircraft landing gear, this paper proposes an optimised design method for an electric actuator based on the principles of tubular permanent magnet linear motor employing a Halbach array. For this electric actuator, a subdomain model considering the longitudinal end effect is established by setting virtual permanent magnet regions at both ends of the Halbach array. The effectiveness of the proposed method is verified through a comparison with the finite element method. Subsequently, a surrogate model is developed using the proposed subdomain model, and an uncertain optimisation model considering machining and assembly errors is developed based on the interval possibility and the interval order theory. Compared to its initial design, the optimised structure increased the average thrust by 13.4% and reduced the thrust ripple rate by 87.2%, significantly improving the overall performance of the electric actuator. Finally, prototype experiments are carried out to verify the effectiveness of the proposed subdomain method and optimised approach.
Error analysis and correction strategy for measuring oriented silicon steel by SST method
Authors: Wang Xinyang , Xue Runfeng , Ma Guang
Published: September 2024

To accurately determine the relationship between magnetic polarisation and magnetic field strength in oriented silicon steel, the magnetic properties, such as power loss, were measured under different magnetisation conditions. This facilitates for the precise selection of iron core materials for distribution transformers. The deviation rate of measurement results for different magnetisation conditions in oriented silicon steel with varying thicknesses was analysed using the SST method. Additionally, the finite element simulation of MagNet was employed to further investigate this relationship. The causes of measurement errors in oriented silicon steel by the SST method are thoroughly studied, with a focus on 0.18 mm oriented silicon steel as an example. It is found that the main reason for the measurement error is the deviation between the actual effective magnetic path length and the conventional effective magnetic path length, which is caused by the uneven distribution of magnetic polarisation in oriented silicon steel. The main reason for the difference of magnetisation conditions is the change in the actual effective magnetic path length, which is mainly affected by changes in permeability. Combined with the magnetic field distribution inside the oriented silicon steel, the distribution coefficient of magnetic polarisation can be calculated, the actual effective magnetic path length under each condition can be calculated, and then the measurement results of the SST method can be modified. This research is expected to significantly contribute to the practical applications of oriented silicon steel in engineering.
Degradation induced by charge relaxation in silicone gels under the ultra‐fast pulsed electric field
Authors: Gao Teng , He Dongxin , Xu Zhe , Wei Junyu , Xie Shijie , Teyssède Gilbert , Liu Zhizhen , Cui Bin
Published: September 2024

The insulating properties of silicone gel used for silicon carbide‐insulated gate bipolar transistors encapsulation may deteriorate seriously under ultra‐fast pulsed electric fields. The essence of insulation degradation lies in the deterioration of materials caused by dynamic phenomena at microscopic scale, such as charge trapping and detrapping. Different from the steady‐state operating condition, insulating materials exhibit a sharp decrease in their insulating properties when subjected to a rapidly changing electric field. To investigate the insulation failure of silicone gel materials under an ultra‐fast pulsed electric field, Marcus hopping mechanism for charge response is proposed. By calculating the relaxation time with different defects, we characterise the degradation of the materials. According to the force analysis of space charge, the authors establish a relationship between insulation failures and charge relaxation time. Combined with the experimental results on electrical treeing in silicone gel, the feasibility of the theory is verified. The experimental phenomenon can be well explained, that is, the initial voltage of the electrical trees decreased sharply with shortening the edge time of the pulsed electric field, especially on the nanosecond time scale.
Active distribution network fault section location method based on characteristic wave coupling
Authors: Liu Zhiren , Chen Kai , Xie Jinghua , Wu Xiaolong , Lu Wenzhou
Published: September 2024

As distributed generators (DG) and power electronic devices become more integrated, distribution networks have evolved from being passive to active, and power flow has shifted from unidirectional to bidirectional. This transformation has negatively impacted power quality, leading to weakened fault transient attributes and increased harmonic complexities. Consequently, the efficacy of traditional relay protection has diminished, elevating the risk of misoperation or misjudgment and compromising the safety of distribution networks. In response to these challenges, a fault section location method for active distribution network based on characteristic wave coupling is proposed to expand the fault difference. This method explores the principles of characteristic wave coupling, discusses characteristic wave parameter selection theory, examines the start‐up control strategy for characteristic wave coupling, and establishes a protection action criterion by comparing the energy difference of characteristic waves based on the fault identification principle. Subsequently, by utilizing multiple inverter interfaced distributed generators to actively couple characteristic waves into the distribution network during faults, achieves rapid identification and location of fault sections. Finally, the effectiveness of the method is substantiated through simulation results in MATLAB/Simulink and experimental outcomes obtained from a low‐voltage active distribution network experimental platform based on dSPACE1103.
Effect of grid‐following VSCs on frequency distribution of power grid
Authors: Ma Qingyuan , Chen Lei , Li Luyang , Min Yong , Shi Yudan
Published: September 2024

The increasing penetration of grid‐following voltage source converters (GFL‐VSCs) in the power grid has changed the frequency dynamics of the system. GFL‐VSC follows the frequency of the terminal bus using a phase‐locked loop, therefore it does not establish the frequency in the same manner as a synchronous generator. However, previous research has demonstrated that GFL‐VSC without additional frequency controls not only tracks the terminal frequency during the system dynamic process bus also has an influence on it, and derives the relationship between GFL‐VSC and terminal frequency through a simplified model. This paper further derives a more generic relationship considering the influences of q‐axis current and grid voltage amplitude variation, which were ignored in previous research. The relationship has proven to be effective and valid. Several influencing factors are analysed to describe the ability to modify terminal frequency. Then the effect of GFL‐VSCs on the frequency distribution of power grid is studied. The frequency divider formula is improved by incorporating the relationship, which provides a frequency estimation formula applicable for system with multiple GFL‐VSCs. Two system‐level simulations verify the conclusion and related influencing factors are analysed.
Separating the causes of O–C variations in an RR Lyrae star with the Blazhko effect
Authors: Sylla S. , Kolenberg K. , Klotz A. , Colas F. , Baratoux D. , Le Borgne J. F. , Benkhaldoun Z. , Denoux E. , Ndao A. S.
Published: September 2024

Context. To date, puzzlingly few bona fide RR Lyrae stars have been identified in binaries. Binarity in pulsating stars can be revealed through well-timed photometric data over sufficiently long time bases because of the light travel time effect (LTTE) on the pulsations, which manifests as variation in the timings of maximum light in the O−C (observed minus calculated) diagram. However, O−C variations can also have other causes, such as the Blazhko effect or a sudden or gradual change in the main pulsation period.

Aims. We approach this challenge by disentangling the Blazhko effect and period changes from the potential LTTE on V1109 Cas, an RR Lyrae star suspected to be part of a binary system based on its O−C data in the GEOS database. In doing so, we aim to uncover the subtler signals indicative of a companion (LTTE).

Methods. We analysed nine years of ground-based photometric data, using Fourier analysis to model the pulsation modulated by the Blazhko effect. From the fit to the observed light curves, we constructed a refined O−C diagram without the scatter caused by Blazhko modulation. Subsequently, we considered different possible scenarios, because distinguishing intrinsic period changes or breaks from the LTTE is challenging.

Results. If the remaining O−C variation is due to a period break, refining the O−C diagram can almost entirely remove the trends. If we interpret the variation as an LTTE, we can consider possible configurations. While we currently favour a period break as the explanation for the residual O−C variations, more data on the star in the forthcoming years will help reveal whether the O−C variations are due to the LTTE or intrinsic period changes.

Conclusions. Our study, based on a detailed light-curve fitting of V1109 Cas, offers insights into the discernment between Blazhko modulation, intrinsic period breaks, and the LTTE in binary systems. Our results highlight the complexity of determining binarity from O−C data traditionally used for detecting binary motion, calling for caution in this process.
Das respiratorisch-zirkulatorische Modell in der osteopathischen
Praxis
Authors: Tozzi Paolo
Published: September 2024

Das respiratorisch-zirkulatorische Modell ist in der osteopathischen Praxis das
Bezugssystem schlechthin für alle Gase und Flüssigkeiten im Körper, wobei die
aktivierende Kraft in den Flüssigkeiten liegt, in all ihren körperlichen
Ausdrucksformen, v.a. aber in ihrer freien Zirkulation und Oxygenierungswirkung.
Historisch gesehen basiert dieses Modell in vielerlei Hinsicht auf der Arbeit
des amerikanischen Osteopathen Gordon Zink. Da in der osteopathischen
Philosophie die Flüssigkeiten eine herausragende Rolle spielen, in Gesundheit
wie in Krankheit, bei der Untersuchung ebenso wie bei der Behandlung, verkörpert
dieses Modell definitiv die tiefste Essenz der Osteopathie.
Das Ellenbogengelenk: ein Multitalent
Authors: Corts Magga
Published: September 2024

Dieser Artikel zeigt die detaillierte Anatomie des Ellenbogengelenks. Neben
den knöchernen Strukturen werden ausgewählte Muskeln, fasziale Strukturen und
Nervenverläufe betrachtet, die für die Funktionalität und die Pathomechanismen
interessant sind. Dysfunktionen, die sich aus den komplexen anatomischen
Zusammenhängen ergeben können, werden ausführlich beschrieben. Abschließend werden
das Gesamtsystem Körper und die Funktionalität des Ellenbogengelenks und die sich
gegenseitig beeinflussenden Faktoren betrachtet.
Hämoptysen bei schwergradiger OSA
Authors: Garhy Mohamed , Eggers Charlotte , Chwich Chiraz , Haasler Edgar , Schönhofer Bernd
Published: September 2024

Vor dem Hintergrund, dass OSA als klinisch relevante Differenzialdiagnose von Hämoptysen in der Literatur nur sehr selten erwähnt wird, berichten wir über eine Patientin mit seit Längerem bestehenden Hämoptysen, die durch repetitive intrathorakale Negativdrucke infolge schwergradiger obstruktiver schlafbezogener Atmungsstörung verursacht wurden.

Die 56-jährige übergewichtige Patientin (BMI 32 kg/m2), langjährige Raucherin
(40 PY) klagte über ausgeprägte Tagesmüdigkeit und stellte sich vor zwei Jahren im März als
auch letztes Jahr im Sommer wegen seit Längerem bestehenden, mild ausgeprägten Hämoptysen in
unserer Notaufnahme vor.

Endoskopisch kam es jeweils nach Eintreten der Sedierung zum kompletten Kollaps des
Hypopharynx, der mit länger andauernden schweren obstruktiven Apnoen und massiven
inspiratorischen thorakalen Einziehungen einherging. Unmittelbar anschließend traten unter
bronchoskopischer Sicht multiple petechiale und großflächige Schleimhauteinblutungen sowie
frische Blutbeläge auf der Schleimhaut auf. Bei der ersten Vorstellung wünschte die Patientin
keine weitere Diagnostik. Bei der zweiten Vorstellung ergab eine Polysomnografie inkl.
transkutaner CO2-Messungen die Diagnose einer schwergradigen OSA in Kombination mit
Hypoventilation (AHI von 76/h, Entsättigungs-Index: 128/h; mittlerer pCO2-Wert von
56 mmHg). Die Therapie zur Behandlung der schwergradigen OSA bestand in der oronasalen
Überdrucktherapie.

Wir weisen mit dieser Kasuistik auf die allgemein unterschätzte Bedeutung des starken intrathorakalen Negativdrucks bei schwergradiger OSA als mögliche Ursache von Hämoptysen hin.
Endoscopic ultrasound classification for prediction of endoscopic submucosal dissection resectability: PREDICT classification
Authors: Matsuura Noriko , Kato Motohiko , Iwata Kentaro , Miyazaki Kurato , Masunaga Teppei , Kubosawa Yoko , Mizutani Mari , Hayashi Yukie , Takabayashi Kaoru , Takatori Yusaku , Nakayama Atsushi , Okabayashi Koji , Kawakubo Hirofumi , Kitagawa Yuko , Yahagi Naohisa
Published: September 2024

Background and study aims The safety of endoscopic submucosal dissection (ESD) has been reported, and the risk of lymph node metastasis is low for colorectal cancer if depth of invasion is the only non-curative factor on histological evaluation. ESD is increasingly performed even if submucosal (SM) invasion is suspected. However, reports about endoscopic findings for the criteria to predict ESD resectability remain limited. Endoscopic ultrasound (EUS) can directly visualize the tomographic image of the gastrointestinal wall and may help predict ESD resectability. Therefore, we investigated the possibility of predicting ESD resectability using EUS.

Patients and methods We compared the association between EUS findings and pathological results for gastric or colorectal lesions with suspected SM invasion using white light endoscopy between June 2020 and January 2023. EUS findings were grouped based on the status of the underlying the tumor, as follows: Type I, submucosal layer was observed with reproducibility; Type II, submucosal layer not fully visible; and Type III, submucosal layer disrupted and muscularis propria (MP) layer thickened.

Results Forty-one gastric cancer and 22 colorectal cancer cases were analyzed. The proportions of pathological VM0 (no tumor exposed on any vertical margin) for ESD-resected specimens were 89% and 33% for Type I and II, respectively, (P ≤ 0.01). The proportions of cancer involving MP or deeper were significantly higher for Type II/III than for Type I (41% vs 0%, P ≤ 0.01).

Conclusions EUS may have an important role in predicting ESD resectability of gastric and colorectal cancers suspected of having SM invasion.
Zusammenhang zwischen der Fallzahl und Strukturmerkmalen und der
Ergebnisqualität von Perinatalzentren Level 1 für Frühgeborene an der Grenze der
Lebensfähigkeit
Authors: Thomas Teresa , Heller Günther , Rolle Udo , Thome Ulrich
Published: September 2024

Einleitung Die vorliegende Studie untersucht den Zusammenhang zwischen
Fallzahlen, Strukturmerkmalen und Ergebnisqualität, insbesondere für Kinder an
der Grenze der Lebensfähigkeit.

Methoden Es wurden in den Jahren 2010–2015 in PNZ Level 1 erstbehandelte
AOK-versicherte Kinder mit einem Aufnahmegewicht (AG) von 250–1249g
eingeschlossen. Für Kinder an der Grenze der Lebensfähigkeit (250–499g AG)
wurden die Endpunkte Mortalität bzw. Mortalität oder Morbidität untersucht. Zum
Vergleich wurden Kinder mit 500–749g bzw. 750–1249g AG analysiert. Der Einfluss
kategorisierter Fallzahlen (in Quartilen) und Strukturmerkmale
(Universitätsklinikum und Kinderchirurgie) wurde mittels getrennter Regressionen
untersucht und Odds Ratios (OR) sowie mittels Simulationen potenziell
vermeidbare Sterbefälle bzw. schwerwiegende Ereignisse berechnet.

Ergebnisse Kinder mit 250–499g AG wiesen signifikant höhere
Überlebenswahrscheinlichkeiten bei Erstbehandlung in PNZ Level 1 mit einer
geschätzten Fallzahl von 62 Behandlungsfällen (250–1249g AG) pro Jahr (OR: 0,43;
95%–KI: 0,20–0,96) oder in universitären PNZ mit Kinderchirurgie (OR: 0,48;
95%–KI: 0,24–0,93) auf. Auch für Kinder mit 500–749g bzw. 750–1249g AG zeigte
sich ein positiver Einfluss der untersuchten Faktoren.

Schlussfolgerung Neben der Fallzahl haben auch Strukturmerkmale einen
relevanten positiven Einfluss auf die Ergebnisqualität. Zusätzliche
Anforderungen an PNZ mit Blick auf Strukturmerkmale wie auch eine höhere
Mindestmenge würden mit deutlich positiven Effekten auf das Outcome
einhergehen.
Perspektiven von Familien mit (schwer-)kranken Kindern und
Jugendlichen in Niedersachsen: Versorgung und Unterstützung im Fokus – Analyse
der aktuellen Situation und möglicher Unterstützungsangebote
Authors: Toenne Rebecca , Geffron Julia , Höcker Maike , Koch Anika , Guth Theresa , Reinhardt Dirk , Reschke Felix
Published: September 2024

Einleitung Die Versorgung von pflegebedürftigen Kindern und Jugendlichen
im häuslichen Umfeld wird durch den Fachkräftemangel im Pflegesektor verschärft,
was zu Engpässen in der Versorgung führt und pflegende Familien vor große
Herausforderungen stellt. Die Implementierung neuer Versorgungsansätze in
bestehende Strukturen im Gesundheitssystem erweist sich als zentrale
Entwicklungsaufgabe, um betroffene Familien zukünftig gezielt zu
unterstützen.

Methodik Qualitativ explorative Interviewstudie zur Erfassung der
Perspektive von Familien mit (schwer-)kranken Kindern und Jugendlichen auf die
derzeitige Versorgungssituation und mögliche hilfreiche Unterstützungsangebote.
Die Stichprobenziehung erfolgte kriteriengeleitet und die Analyse und Auswertung
inhaltsanalytisch. Zur Erfassung soziodemografischer Merkmale erhielten die
Befragten einen Kurzfragebogen.

Ergebnisse Insbesondere die Übermittlung der Diagnose, die alltäglichen
Herausforderungen sowie der Einfluss auf die Lebensqualität wurden von den n=10
teilnehmenden Erziehungsberechtigten als Belastungsfaktoren benannt. Ein
verbesserter Zugang zu Informationen, ehrenamtlichen Strukturen und zentralen
Anlaufstellen sowie digitalen Angeboten wurden als zentrale Entwicklungsbedarfe
benannt.

Schlussfolgerung Ausgehend von einer lebenswelt- und bedürfnisorientierten
Perspektive kann aus den Interviews die Notwendigkeit des Ausbaus von
niedrigschwelligen Angeboten zur Versorgungskoordination, einer Stärkung
ehrenamtlicher Strukturen sowie der Einsatz telemedizinischer Angebote
abgeleitet werden. Hierdurch soll insbesondere in ländlichen Gebieten der Zugang
zu spezialisierter Behandlung und hilfreichen Angeboten ermöglicht werden.