bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures S2-4 from Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma
Authors: Vatolin Sergei , Phillips James G. , Jha Babal K. , Govindgari Shravya , Hu Jennifer , Grabowski Dale , Parker Yvonne , Lindner Daniel J. , Zhong Fei , Distelhorst Clark W. , Smith Mitchell R. , Cotta Claudiu , Xu Yan , Chilakala Sujatha , Kuang Rebecca R. , Tall Samantha , Reu Frederic J.
Published: April 2023

S2: Inactivation of bortezomib by liver homogenate; S3: CCF642 effect on survival of normal bone marrow, myeloid neoplasia, myeloma and lymphoma cells; S4: Biotin-stained Western blot after treatment of MM1.S cells with B-CCF642
Supplemental Table S1 from Osteogenic Potential of Mesenchymal Stromal Cells Contributes to Primary Myelofibrosis
Authors: Martinaud Christophe , Desterke Christophe , Konopacki Johanna , Pieri Lisa , Torossian Frédéric , Golub Rachel , Schmutz Sandrine , Anginot Adrienne , Guerton Bernadette , Rochet Nathalie , Albanese Patricia , Henault Emilie , Pierre-Louis Olivier , Souraud Jean-Baptiste , de Revel Thierry , Dupriez Brigitte , Ianotto Jean-Christophe , Bourgeade Marie-Françoise , Vannucchi Alessandro M. , Lataillade Jean-Jacques , Le Bousse-Kerdilès Marie-Caroline
Published: April 2023

Primers used for RQ-PCR.
Supplementary Figures S1-7 from GON4L Drives Cancer Growth through a YY1–Androgen Receptor–CD24 Axis
Authors: Agarwal Neeraj , Dancik Garrett M. , Goodspeed Andrew , Costello James C. , Owens Charles , Duex Jason E. , Theodorescu Dan
Published: April 2023

Figure S1 - Expression pattern of CD24 in different cell lines used and effect of candidate gene depletion on CD24 protein levels. Figure S2 - siRNA dose-dependent GON4L knockdown and STRING analysis for GON4L interactions. Figure S3 - Effect of YY1 knockdown on GON4L mRNA levels. Figure S4 - Effect of GON4L and YY1 knockdown on tumor growth in vivo and their expression in bladder cancer. Figure S5 - Luciferase reporter assays in control plasmids, endogenous CO-IP for AR and YY1 interaction, and effect of GON4L and YY1 knockdown on AR expression. Figure S6 - AR expression levels in different cancer cell lines, and GON4L and YY1 knockdown as measured by qRT-PCR. Figure S7 - GON4L and YY1 knockdown in AR- cancer cell lines.
Supplemental methods from An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression
Authors: Hayashi Hiromitsu , Higashi Takaaki , Yokoyama Naomi , Kaida Takayoshi , Sakamoto Keita , Fukushima Yukiko , Ishimoto Takatsugu , Kuroki Hideyuki , Nitta Hidetoshi , Hashimoto Daisuke , Chikamoto Akira , Oki Eiji , Beppu Toru , Baba Hideo
Published: April 2023

Supplemental methods
Supplemental Figure 2: Small intestinal crypt-villus length and HuR subcellular distribution in tumors. from HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis
Authors: Lang Michaela , Berry David , Passecker Katharina , Mesteri Ildiko , Bhuju Sabin , Ebner Florian , Sedlyarov Vitaly , Evstatiev Rayko , Dammann Kyle , Loy Alexander , Kuzyk Orest , Kovarik Pavel , Khare Vineeta , Beibel Martin , Roma Guglielmo , Meisner-Kober Nicole , Gasche Christoph
Published: April 2023

Crypt-villus length and HuR subcellular distribution as analyzed by immunohistochemistry and Western blot of nuclear and cytoplasmic fractions from isolated tumors in MS-444 treated and control mice.
Supplemental figure 1 from An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell–like Behaviors Contributing to Disease Progression
Authors: Hayashi Hiromitsu , Higashi Takaaki , Yokoyama Naomi , Kaida Takayoshi , Sakamoto Keita , Fukushima Yukiko , Ishimoto Takatsugu , Kuroki Hideyuki , Nitta Hidetoshi , Hashimoto Daisuke , Chikamoto Akira , Oki Eiji , Beppu Toru , Baba Hideo
Published: April 2023

Knockdown of TAZ or YAP expression by siRNA duplex oligonucleotides.
Suppl. Table 1 from HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors
Authors: Budina-Kolomets Anna , Webster Marie R. , Leu Julia I-Ju , Jennis Matthew , Krepler Clemens , Guerrini Anastasia , Kossenkov Andrew V. , Xu Wei , Karakousis Giorgos , Schuchter Lynn , Amaravadi Ravi K. , Wu Hong , Yin Xiangfan , Liu Qin , Lu Yiling , Mills Gordon B. , Xu Xiaowei , George Donna L. , Weeraratna Ashani T. , Murphy Maureen E.
Published: April 2023

Coefficient of interaction (CI) values for PET-16 and targeted therapeutic agent PLX4032 in BRAF V600E melanoma cell lines.
Supplementary Figure 6. from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary Figure 6. EGI-1 cells but not TFK-1 cells contained SUMOylated S100A4; inhibitory effects of low dose PTX on SUMOylating complex did not associate with any deregulation of SUMO E subunits.
Supplementary Figure 2 from Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma
Authors: Cadamuro Massimiliano , Spagnuolo Gaia , Sambado Luisa , Indraccolo Stefano , Nardo Giorgia , Rosato Antonio , Brivio Simone , Caslini Chiara , Stecca Tommaso , Massani Marco , Bassi Nicolò , Novelli Eugenio , Spirli Carlo , Fabris Luca , Strazzabosco Mario
Published: April 2023

Supplementary Figure 2. Low dose PTX reduced motility and invasiveness of CCA-TV3 cells.
Supplemental materials and methods from A Radiotracer Strategy to Quantify PARP-1 Expression In Vivo Provides a Biomarker That Can Enable Patient Selection for PARP Inhibitor Therapy
Authors: Makvandi Mehran , Xu Kuiying , Lieberman Brian P. , Anderson Redmond-Craig , Effron Samuel Sander , Winters Harrison D. , Zeng Chenbo , McDonald Elizabeth S. , Pryma Daniel A. , Greenberg Roger A. , Mach Robert H.
Published: April 2023

Supplemental material and methods.
Supplemental Figures and Tables from A Radiotracer Strategy to Quantify PARP-1 Expression In Vivo Provides a Biomarker That Can Enable Patient Selection for PARP Inhibitor Therapy
Authors: Makvandi Mehran , Xu Kuiying , Lieberman Brian P. , Anderson Redmond-Craig , Effron Samuel Sander , Winters Harrison D. , Zeng Chenbo , McDonald Elizabeth S. , Pryma Daniel A. , Greenberg Roger A. , Mach Robert H.
Published: April 2023

SI-figure 1: "Chemical synthesis scheme for [125I]KX1." SI-figure 2: "Whole western blots and regions of interest generated around the protein of interest." SI-figure 3: "Kinetic analysis association and dissociation curves of [125I]KX1." SI-table 1: "Summary table for cell lines used in vitro to validate [125I]KX1 as a marker of PARP-1 expression." SI-table 2: "Competitive inhibition (Ki) Values are presented for each PARP inhibitor as measured in the different cell lines." SI-table 3: "Experimental association and dissociation values of [125I]KX1." SI-table 4: "Dissociation constants for [125I]KX1 in multiple cell lines." SI-table 5: " EC50 values for PARP inhibitors in cell lines evaluated."
Supplemental Figure 1 from IL17 Functions through the Novel REG3β–JAK2–STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer
Authors: Loncle Celine , Bonjoch Laia , Folch-Puy Emma , Lopez-Millan Maria Belen , Lac Sophie , Molejon Maria Inés , Chuluyan Eduardo , Cordelier Pierre , Dubus Pierre , Lomberk Gwen , Urrutia Raul , Closa Daniel , Iovanna Juan L.
Published: April 2023

Schematic representation of the IL-17A and REG3β signaling pathway and PDAC development.
Figure S6 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: April 2023

KDM5i and DAC do not synergize in MCF10A, nor alter cell cycle in MCF-7
Figure S4 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: April 2023

Differential H3K4me3 enrichment profiling after KDM5i, DAC, or both
Figure S2 from A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2′-Deoxycytidine
Authors: Leadem Benjamin R. , Kagiampakis Ioannis , Wilson Catherine , Cheung Tommy K. , Arnott David , Trojer Patrick , Classon Marie , Easwaran Hariharan , Baylin Stephen B.
Published: April 2023

DAC & KDM5i induced expression changes
Supplementary Table 1 from Ras Signaling Is a Key Determinant for Metastatic Dissemination and Poor Survival of Luminal Breast Cancer Patients
Authors: Wright Katherine L. , Adams Jessica R. , Liu Jeff C. , Loch Amanda J. , Wong Ruth G. , Jo Christine E.B. , Beck Lauren A. , Santhanam Divya R. , Weiss Laura , Mei Xue , Lane Timothy F. , Koralov Sergei B. , Done Susan J. , Woodgett James R. , Zacksenhaus Eldad , Hu Pingzhao , Egan Sean E.
Published: April 2023

Supplementary Table 1. Kaplan-Meier survival statistics for control and experimental mice: This table presents results of analysis on tumor assays.
Supplementary Table 5 and 6 from MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome
Authors: Wragg Joseph W. , Finnity Jonathan P. , Anderson Jane A. , Ferguson Henry J.M. , Porfiri Emilio , Bhatt Rupesh I. , Murray Paul G. , Heath Victoria L. , Bicknell Roy
Published: April 2023

Supplementary Table 5: Matrix metallopeptidase regulation across tissue types (Gene expression comparison shown as Log2 fold change) Supplementary Table 6: Collagen regulation across tissue types (Gene expression comparison shown as Log2 fold change)
Supplementary Table 5 from An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers
Authors: Prueitt Robyn L. , Wallace Tiffany A. , Glynn Sharon A. , Yi Ming , Tang Wei , Luo Jun , Dorsey Tiffany H. , Stagliano Katherine E. , Gillespie John W. , Hudson Robert S. , Terunuma Atsushi , Shoe Jennifer L. , Haines Diana C. , Yfantis Harris G. , Han Misop , Martin Damali N. , Jordan Symone V. , Borin James F. , Naslund Michael J. , Alexander Richard B. , Stephens Robert M. , Loffredo Christopher A. , Lee Dong H. , Putluri Nagireddy , Sreekumar Arun , Hurwitz Arthur A. , Ambs Stefan
Published: April 2023

Supplemetary Table 5: Genes differently expressed between current and never and between current and past/never smokers in the combined cohort of 67 prostate tumors
Supplementary Figure 1 from Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients
Authors: De Monte Lucia , Wörmann Sonja , Brunetto Emanuela , Heltai Silvia , Magliacane Gilda , Reni Michele , Paganoni Anna Maria , Recalde Helios , Mondino Anna , Falconi Massimo , Aleotti Francesca , Balzano Gianpaolo , Algül Hana , Doglioni Claudio , Protti Maria Pia
Published: April 2023

Expression of CCL24/eotaxin-2 in CAF supernatant-conditioned monocytes and in TDLNs.
Supplementary Tables S1-S4 from Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma
Authors: Hijiya Naoki , Tsukamoto Yoshiyuki , Nakada Chisato , Tung Nguyen Lam , Kai Tomoki , Matsuura Keiko , Shibata Kohei , Inomata Masafumi , Uchida Tomohisa , Tokunaga Akinori , Amada Kohei , Shirao Kuniaki , Yamada Yasunari , Mori Hiromu , Takeuchi Ichiro , Seto Masao , Aoki Masahiro , Takekawa Mutsuhiro , Moriyama Masatsugu
Published: April 2023

Clinicopathologic characteristics of 10 cases of IPMN-inv (S1); Chromosomal imbalances frequently detected in IPMN-inv (S2); Clinicopathologic characteristics of 19 cases of IDC (S3); Comparison of frequent chromosomal aberrations in IDC with those in the invasive region of IPMN-inv (S4).
Supplementary figure 2 from miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis
Authors: Xue Jianfei , Zhou Aidong , Wu Yamei , Morris Saint-Aaron , Lin Kangyu , Amin Samirkumar , Verhaak Roeland , Fuller Gregory , Xie Keping , Heimberger Amy B. , Huang Suyun
Published: April 2023

Supplementary figure 2
Supplementary Table S1 from Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
Authors: Pasero Christine , Gravis Gwenaëlle , Guerin Mathilde , Granjeaud Samuel , Thomassin-Piana Jeanne , Rocchi Palma , Paciencia-Gros Maria , Poizat Flora , Bentobji Mélanie , Azario-Cheillan Francine , Walz Jochen , Salem Naji , Brunelle Serge , Moretta Alessandro , Olive Daniel
Published: April 2023

Characteristics of prostate tumors.
Supplementary Figure S2 from Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
Authors: Pasero Christine , Gravis Gwenaëlle , Guerin Mathilde , Granjeaud Samuel , Thomassin-Piana Jeanne , Rocchi Palma , Paciencia-Gros Maria , Poizat Flora , Bentobji Mélanie , Azario-Cheillan Francine , Walz Jochen , Salem Naji , Brunelle Serge , Moretta Alessandro , Olive Daniel
Published: April 2023

Mechanisms of NKp46 and NKG2D downregulation in tumors.
Supplementary Figure S3 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus
Authors: Harlow Matt L. , Maloney Nichole , Roland Joseph , Guillen Navarro Maria Jose , Easton Matthew K. , Kitchen-Goosen Susan M. , Boguslawski Elissa A. , Madaj Zachary B. , Johnson Ben K. , Bowman Megan J. , D'Incalci Maurizio , Winn Mary E. , Turner Lisa , Hostetter Galen , Galmarini Carlos María , Aviles Pablo M. , Grohar Patrick J.
Published: April 2023

Supplementary Figure S3 Single-cell imaging of HA-tagged TC32 cells treated with 2.5 nM trabectedin or lurbinectedin for 6 h shows EWS-FLI1 (green) localized into the nucleolus (red). DAPI (blue) staining of the nucleus.
Suppl Table S7 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

Genomic alterations in LARP4B in human acute myeloid leukemia
Suppl Table S6 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

Genomic alterations in LARP family genes in human glioblastoma
Supplementary Figure S1 from Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus
Authors: Harlow Matt L. , Maloney Nichole , Roland Joseph , Guillen Navarro Maria Jose , Easton Matthew K. , Kitchen-Goosen Susan M. , Boguslawski Elissa A. , Madaj Zachary B. , Johnson Ben K. , Bowman Megan J. , D'Incalci Maurizio , Winn Mary E. , Turner Lisa , Hostetter Galen , Galmarini Carlos María , Aviles Pablo M. , Grohar Patrick J.
Published: April 2023

Supplementary Figure S1 A) Agarose gel showing single NR0B1 product from U20S and TC32 cells. B) Sequencing of single NR0B1 band shown in A.
Suppl Table S5 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

Genomic alterations in candidate tumor suppressor genes in human low-grade glioma
Supplementary methods from A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies
Authors: Zhang Yongliang , Fox Jennifer T. , Park Young-Un , Elliott Gene , Rai Ganesha , Cai Mengli , Sakamuru Srilatha , Huang Ruili , Xia Menghang , Lee Kyeryoung , Jeon Min Ho , Mathew Bijoy P. , Park Hee Dong , Edelmann Winfried , Park Chan Young , Hong Sung You , Maloney David , Myung Kyungjae
Published: April 2023

This file has methods used in the study in addition to methods described in the manuscript.
Supplementary Figures from A Novel Chemotherapeutic Agent to Treat Tumors with DNA Mismatch Repair Deficiencies
Authors: Zhang Yongliang , Fox Jennifer T. , Park Young-Un , Elliott Gene , Rai Ganesha , Cai Mengli , Sakamuru Srilatha , Huang Ruili , Xia Menghang , Lee Kyeryoung , Jeon Min Ho , Mathew Bijoy P. , Park Hee Dong , Edelmann Winfried , Park Chan Young , Hong Sung You , Maloney David , Myung Kyungjae
Published: April 2023

Supplemental Figures contains supplementary figures S1-S13. Supplementary Figure S1. The effect of MSH2 deficiency on cell sensitivity to baicalein. Supplementary Figure S2. Baicalein-treated HEC59 cells are deficient in CHK2-regulated S phase checkpoint arrest. Supplementary Figure S3. Baicalein disrupts the interaction between MutSα and CHK2-ATM. Supplementary Figure S4. Baicalein binds to MutSα. Supplementary Figure S5. Baicalein intercalates DNA but does not form crosslinks. Supplementary Figure S6. XPF deficiency reduces baicalein-induced γ-H2AX and rescues baicalein-induced cell death in HT29 MSH2-deficient cells. Supplementary Figure S7. Baicalein pellets reduce the size of MSH2-deficient xenograft tumors but have little effect on MSH2-proficient tumors. Supplementary Figure S8. Baicalein shrinks MSH2-deficient xenograft tumors in a time-dependent manner. Supplementary Figure S9. Baicalein shrinks xenograft tumors formed by MSH2-deficient LoVo cells. Supplementary Figure S10. Baicalein inhibits the growth of chronic-AOM-DSS-induced colon tumors in Msh2LoxP/LoxPVilCre mice. Supplementary Figure S11. Baicalein inhibits the growth of acute-AOM-DSS-induced colon tumors in Msh2LoxP/LoxPVilCre mice. Supplementary Figure S12. Baicalein have little effect on the growth of chronic-AOM-DSS-induced colon tumors in WT mice. Supplementary Figure S13. Model describing baicalein's mechanism of action.
Suppl Figure S4 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

Larp4b loss promotes tumor cell growth in the brain
Suppl Figure S3 from Identification of RNA-Binding Protein LARP4B as a Tumor Suppressor in Glioma
Authors: Koso Hideto , Yi Hungtsung , Sheridan Paul , Miyano Satoru , Ino Yasushi , Todo Tomoki , Watanabe Sumiko
Published: April 2023

Gating strategies for flow cytometry analysis
Supplementary Table 1 from Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Authors: Colli Leandro M. , Machiela Mitchell J. , Myers Timothy A. , Jessop Lea , Yu Kai , Chanock Stephen J.
Published: April 2023

Comparing previous NSCLC and melanoma studies of checkpoint inhibition response regarding an NsM estimated ROC analysis threshold
Supplementary Figure 3 from Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Authors: Colli Leandro M. , Machiela Mitchell J. , Myers Timothy A. , Jessop Lea , Yu Kai , Chanock Stephen J.
Published: April 2023

Violin plot for the number of non-synonymous mutations for stage I and II patients (light gray) and stage III and IV patients (dark gray).
Support Information from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

Supplementary Materials and Methods and Figure Legends.
Figure S8 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

Wound healing assay of KHOS/NP cells infected with lentivirus-WSB1, lentivirus-RhoGDI2, lentivirus-WSB1 plus lentivirus-RhoGDI2, or control lentivirus (pCCL).
Supplementary Figure 1 from Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses
Authors: Colli Leandro M. , Machiela Mitchell J. , Myers Timothy A. , Jessop Lea , Yu Kai , Chanock Stephen J.
Published: April 2023

Violin plot for the number of non-synonymous mutations for TCGA set (light gray) and replication set (dark gray) for skin cutaneous melanoma (SKCM), lung adenocarcinoma (LUAD), head and neck squamous cell carcinoma (HNSC), breast invasive carcinoma (BRCA), and prostate adenocarcinoma (PRAD).
Figure S5 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

(A) Correlation between RhoGDI2 expression levels and metastatic potential in osteosarcoma patients. (B) Cells were exposed to hypoxia for 24 h or cells infected with control lentivirus (pCCL) and lentivirus-WSB1. RhoGDI2 mRNA expression was analyzed by RT-PCR and shown as a histogram after normalization, β-Actin was used as a control gene. (C) KHOS/NP cells treated with hypoxia for 24h together with 10 μM MG132, and RhoGDI2 protein levels were measured by western-blot analysis. (D) Colocalization of endogenous WSB1 and RhoGDI2. KHOS/NP cells were subjected to immunofluorescence staining with anti-WSB1 and anti-RhoGDI2 antibodies.
Figure S4 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

The discovery of downstream signaling of WSB1 via SILAC assay.
Figure S3 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

H&E staining of lung tissues in tail vein injection of KHOS/NP cells were performed in BALB/c (nu/nu) mice.
Supplementary Materials from The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling
Authors: Peng Chenghao , Chen Zhengxin , Wang Shuai , Wang Hong-Wei , Qiu Wenjin , Zhao Lin , Xu Ran , Luo Hui , Chen Yuanyuan , Chen Dan , You Yongping , Liu Ning , Wang Huibo
Published: April 2023

Supplementary Materials and Supplementary Figure Legend
Figure S2 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

Wound healing assay of KHOS/NP cells infected with lentivirus-WSB1 or control lentivirus (pCCL.)
Figure S1 from Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells
Authors: Cao Ji , Wang Yijie , Dong Rong , Lin Guanyu , Zhang Ning , Wang Jing , Lin Nengming , Gu Yongchuan , Ding Ling , Ying Meidan , He Qiaojun , Yang Bo
Published: April 2023

Plasmid constructs and the validation of infection efficiency by GFP expression.
Supplementary Figure 2 from The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling
Authors: Peng Chenghao , Chen Zhengxin , Wang Shuai , Wang Hong-Wei , Qiu Wenjin , Zhao Lin , Xu Ran , Luo Hui , Chen Yuanyuan , Chen Dan , You Yongping , Liu Ning , Wang Huibo
Published: April 2023

Labelling protocol for DNA fiber analysis in U87 Pol κ-depleted or control cells
Supplemental Figure Legends from MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer
Authors: Cichon Magdalena A. , Moruzzi Megan E. , Shqau Tiziana A. , Miller Erin , Mehner Christine , Ethier Stephen P. , Copland John A. , Radisky Evette S. , Radisky Derek C.
Published: April 2023

Legends for Supplemental Figures S1-S5.
Supplementary Table S2 from Multiple Myeloma Impairs Bone Marrow Localization of Effector Natural Killer Cells by Altering the Chemokine Microenvironment
Authors: Ponzetta Andrea , Benigni Giorgia , Antonangeli Fabrizio , Sciumè Giuseppe , Sanseviero Emilio , Zingoni Alessandra , Ricciardi Maria Rosaria , Petrucci Maria Teresa , Santoni Angela , Bernardini Giovanni
Published: April 2023

Supplementary Table S2. Expression of chemokine genes by BM cell populations
Supplementary Table S1 from Multiple Myeloma Impairs Bone Marrow Localization of Effector Natural Killer Cells by Altering the Chemokine Microenvironment
Authors: Ponzetta Andrea , Benigni Giorgia , Antonangeli Fabrizio , Sciumè Giuseppe , Sanseviero Emilio , Zingoni Alessandra , Ricciardi Maria Rosaria , Petrucci Maria Teresa , Santoni Angela , Bernardini Giovanni
Published: April 2023

Supplementary Table S1. Patient characteristics
Supplemental Figure S17 from Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes
Authors: Markowitz Geoffrey J. , Yang Pengyuan , Fu Jing , Michelotti Gregory A. , Chen Rui , Sui Jianhua , Yang Bin , Qin Wen-Hao , Zhang Zheng , Wang Fu-Sheng , Diehl Anna Mae , Li Qi-Jing , Wang Hongyang , Wang Xiao-Fan
Published: April 2023

Supplementary Fig. S17. Representative immunohistochemistry showing intratumoral, peritumoral, and marginal tissue stained for IL-18 from patients.
Supplementary Figure S1 from Multiple Myeloma Impairs Bone Marrow Localization of Effector Natural Killer Cells by Altering the Chemokine Microenvironment
Authors: Ponzetta Andrea , Benigni Giorgia , Antonangeli Fabrizio , Sciumè Giuseppe , Sanseviero Emilio , Zingoni Alessandra , Ricciardi Maria Rosaria , Petrucci Maria Teresa , Santoni Angela , Bernardini Giovanni
Published: April 2023

Supplementary Figure S1. Chemokine expression in serum and spleen of healthy control or MM-bearing mice and 5TGM1 culture supernatants
Supplementary Figures 1 through 3 from CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination
Authors: Ahrends Tomasz , Bąbała Nikolina , Xiao Yanling , Yagita Hideo , van Eenennaam Hans , Borst Jannie
Published: April 2023

Supplementary figures containing vaccine design, FACS plots and supporting data on other costimulatory molecules addressed in the manuscript.
Table S1 from Upregulated Glucose Metabolism Correlates Inversely with CD8+ T-cell Infiltration and Survival in Squamous Cell Carcinoma
Authors: Ottensmeier Christian H. , Perry Kate L. , Harden Elena L. , Stasakova Jana , Jenei Veronika , Fleming Jason , Wood Oliver , Woo Jeongmin , Woelk Christopher H. , Thomas Gareth J. , Thirdborough Stephen M.
Published: April 2023

Table S1. Complete list of identified modules in the HNSC network and their top GO Biological Process category.
Figure S5 from Upregulated Glucose Metabolism Correlates Inversely with CD8+ T-cell Infiltration and Survival in Squamous Cell Carcinoma
Authors: Ottensmeier Christian H. , Perry Kate L. , Harden Elena L. , Stasakova Jana , Jenei Veronika , Fleming Jason , Wood Oliver , Woo Jeongmin , Woelk Christopher H. , Thomas Gareth J. , Thirdborough Stephen M.
Published: April 2023

Figure S5. Magnitude and breadth of T-cell response to HPV-16 E7/E6 DNA vaccine. The E7/E6 DNA vaccine (VB1025) was obtained from Agnete Fredriksen and Ole Brekke (Vaccibody, Oslo, Norway). It encodes a HPV-16 E7/E6 fusion protein, which for safety reasons, has mutations at E7 position 24 (Cys to Gly) and 26 (Glu to Gly), and E6 position 63 (Cys to Arg) and 106 (Cys to Arg). C57BL/6J mice were immunized with a total of 50 µg of empty vector or VB1025 plasmid DNA in normal saline injected into both quadriceps. After 12 days, the number of epitope-specific T-cells induced was assayed directly ex vivo by IFN-γ ELISPOT. Overlapping 15-mer peptide pools (5 per pool) spanning the E7/E6 fusion protein or the nominal CD8+ T-cell epitopes RAHYNIVTF (derived from E7 and represented in pool 3) and EVYDFAARR (derived from E6 and represented in pool 8) were used to determine the breadth of the response. Each assay was performed in triplicate, and the experimental values were expressed as the mean net spots/106 splenocytes {plus minus} SD of the mean for each peptide pool tested. The results shown are representative of two separate experiments, with each column representing an individual mouse.
Supplemental Table S3 from Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression
Authors: De Smedt Eva , Maes Ken , Verhulst Stefaan , Lui Hui , Kassambara Alboukadel , Maes Anke , Robert Nicolas , Heirman Carlo , Cakana Andrew , Hose Dirk , Breckpot Karine , van Grunsven Leo A. , De Veirman Kim , Menu Eline , Vanderkerken Karin , Moreaux Jérôme , De Bruyne Elke
Published: April 2023

Pathway enrichment analysis of genes downregulated after RASSF4 overexpression in human multiple myeloma cell lines
Supplemental Table S2 from Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression
Authors: De Smedt Eva , Maes Ken , Verhulst Stefaan , Lui Hui , Kassambara Alboukadel , Maes Anke , Robert Nicolas , Heirman Carlo , Cakana Andrew , Hose Dirk , Breckpot Karine , van Grunsven Leo A. , De Veirman Kim , Menu Eline , Vanderkerken Karin , Moreaux Jérôme , De Bruyne Elke
Published: April 2023

List of differentially expressed genes between all control and RASSF4 overexpressing human multiple myeloma cell lines
Figure S1 from Upregulated Glucose Metabolism Correlates Inversely with CD8+ T-cell Infiltration and Survival in Squamous Cell Carcinoma
Authors: Ottensmeier Christian H. , Perry Kate L. , Harden Elena L. , Stasakova Jana , Jenei Veronika , Fleming Jason , Wood Oliver , Woo Jeongmin , Woelk Christopher H. , Thomas Gareth J. , Thirdborough Stephen M.
Published: April 2023

Figure S1. Overview of workflow.
Supplemental Figures S1-S7 from Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression
Authors: De Smedt Eva , Maes Ken , Verhulst Stefaan , Lui Hui , Kassambara Alboukadel , Maes Anke , Robert Nicolas , Heirman Carlo , Cakana Andrew , Hose Dirk , Breckpot Karine , van Grunsven Leo A. , De Veirman Kim , Menu Eline , Vanderkerken Karin , Moreaux Jérôme , De Bruyne Elke
Published: April 2023

Supplemental Figure 1 shows the prognostic value of the classical RASSF proteins RASSF1, RASSF3, RASSF5 and RASSF6 in MM patients. Supplemental Figure S2 shows the cellular localization of RASSF4. Supplemental Figure S3 demonstrates the inducible doxycycline-dependent overexpression of human RASSF4 and provides additional evidence for the anti-myeloma activity of RASSF4 overexpression in human cell lines. Supplemental Figure S4 provides a comparison of the RASSF4 expression levels of the primary MM cells (n=10) and a selected panel of HMCL (n=9) obtained through microarray analysis. Supplemental Figure S5 shows additional data on the effect of RASSF4 overexpression on tumor development and the confirmation of RASSF4 overexpression on protein level. Supplemental Figure S6 provides an overview of the top 20 differentially expressed genes between all control and RASSF4 overexpressing human multiple myeloma cell lines and subsequent pathway enrichment analysis of the genes downregulated after RASSF4 overexpression. Supplemental Figure S7 provides additional evidence for the anti-myeloma activity of trametinib in combination with the HDACi quisinostat or panobinostat and shows the effect of the HDACi panobinostat and/or the MEK1/2 inhibitor trametinib on RASSF4 mRNA expression.
Supplementary Figure 6 from Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer
Authors: Rao Chinthalapally V. , Janakiram Naveena B. , Madka Venkateshwar , Kumar Gaurav , Scott Edgar J. , Pathuri Gopal , Bryant Taylor , Kutche Hannah , Zhang Yuting , Biddick Laura , Gali Hariprasad , Zhao Yan D. , Lightfoot Stan , Mohammed Altaf
Published: April 2023

Images showing binding of talniflumate to GCNT3
Supplementary Figure 5 from Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer
Authors: Rao Chinthalapally V. , Janakiram Naveena B. , Madka Venkateshwar , Kumar Gaurav , Scott Edgar J. , Pathuri Gopal , Bryant Taylor , Kutche Hannah , Zhang Yuting , Biddick Laura , Gali Hariprasad , Zhao Yan D. , Lightfoot Stan , Mohammed Altaf
Published: April 2023

Effect of talniflumate and gefitinib on mRNA expression of Muc4 and Muc5ac in human pancreatic cancer cell lines
Supplementary Tables from Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway
Authors: Jakubek Yasminka , Lang Wenhua , Vattathil Selina , Garcia Melinda , Xu Li , Huang Lili , Yoo Suk-Young , Shen Li , Lu Wei , Chow Chi-Wan , Weber Zachary , Davies Gareth , Huang Jing , Behrens Carmen , Kalhor Neda , Moran Cesar , Fujimoto Junya , Mehran Reza , El-Zein Randa , Swisher Stephen G. , Wang Jing , Fowler Jerry , Spira Avrum E. , Ehli Erik A. , Wistuba Ignacio I. , Scheet Paul , Kadara Humam
Published: April 2023

Supplementary Tables 1-3 Supplementary Table 1. Location and number of NSCLC, normal and field of cancerization specimens analyzed for genome-wide allelic imbalance Supplementary Table 2. Summary of identified allelic imbalance events in the normal-appearing airway field of cancerization in early-stage NSCLC Supplementary Table 3. Airway events with negative B-allele frequency correlations
Supplementary Figure 4 from Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer
Authors: Rao Chinthalapally V. , Janakiram Naveena B. , Madka Venkateshwar , Kumar Gaurav , Scott Edgar J. , Pathuri Gopal , Bryant Taylor , Kutche Hannah , Zhang Yuting , Biddick Laura , Gali Hariprasad , Zhao Yan D. , Lightfoot Stan , Mohammed Altaf
Published: April 2023

Effect of talniflumate and gefitinib on GCNT3, PCNA, cyclin D1 and mucin protein levels in human pancreatic cancer cells
Supplementary Figure 3 from Small-Molecule Inhibition of GCNT3 Disrupts Mucin Biosynthesis and Malignant Cellular Behaviors in Pancreatic Cancer
Authors: Rao Chinthalapally V. , Janakiram Naveena B. , Madka Venkateshwar , Kumar Gaurav , Scott Edgar J. , Pathuri Gopal , Bryant Taylor , Kutche Hannah , Zhang Yuting , Biddick Laura , Gali Hariprasad , Zhao Yan D. , Lightfoot Stan , Mohammed Altaf
Published: April 2023

mRNA expression of GCNT3 and Cell viability of human pancreatic cancer cells upon treatment with a combination of talniflumate and gefitinib
Figure S8 from TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis
Authors: Principe Daniel R. , DeCant Brian , Mascariñas Emman , Wayne Elizabeth A. , Diaz Andrew M. , Akagi Naomi , Hwang Rosa , Pasche Boris , Dawson David W. , Fang Deyu , Bentrem David J. , Munshi Hidayatullah G. , Jung Barbara , Grippo Paul J.
Published: April 2023

Figure S8. Adaptive Immunity is Dispensable for KRAS-Induced Lesion Development in Vivo
Figure S6 from TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis
Authors: Principe Daniel R. , DeCant Brian , Mascariñas Emman , Wayne Elizabeth A. , Diaz Andrew M. , Akagi Naomi , Hwang Rosa , Pasche Boris , Dawson David W. , Fang Deyu , Bentrem David J. , Munshi Hidayatullah G. , Jung Barbara , Grippo Paul J.
Published: April 2023

Figure S6. Global TGFBR-Deficiency does not Alter Non-Peripheral Tregs
Figure S3 from TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis
Authors: Principe Daniel R. , DeCant Brian , Mascariñas Emman , Wayne Elizabeth A. , Diaz Andrew M. , Akagi Naomi , Hwang Rosa , Pasche Boris , Dawson David W. , Fang Deyu , Bentrem David J. , Munshi Hidayatullah G. , Jung Barbara , Grippo Paul J.
Published: April 2023

FiguFigure S3. Systemic TGFBR Deficiency Attenuates the Tumor Permissive Phenotype of KTE Mice
Supplementary Figure S2 from Heparanase 2 Attenuates Head and Neck Tumor Vascularity and Growth
Authors: Gross-Cohen Miriam , Feld Sari , Doweck Ilana , Neufeld Gera , Hasson Peleg , Arvatz Gil , Barash Uri , Naroditsky Inna , Ilan Neta , Vlodavsky Israel
Published: April 2023

Over expression of Hpa2 is associated with increased apoptosis, cytokeratin expression and tumor hypoxia.
Supplementary Materials and Methods from Systemic DC Activation Modulates the Tumor Microenvironment and Shapes the Long-Lived Tumor-Specific Memory Mediated by CD8+ T Cells
Authors: Shimizu Kanako , Yamasaki Satoru , Shinga Jun , Sato Yusuke , Watanabe Takashi , Ohara Osamu , Kuzushima Kiyotaka , Yagita Hideo , Komuro Yoshiko , Asakura Miki , Fujii Shin-ichiro
Published: April 2023

Supplemental Material and Methods
Supplemental Figure 3 Characterization of FIP1C/ErbB2/neuNDL cell lines in regulating tumor growth using athymic NCr mice from Rab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary Tumor Progression
Authors: Boulay Pierre-Luc , Mitchell Louise , Turpin Jason , Huot-Marchand Julie-Émilie , Lavoie Cynthia , Sanguin-Gendreau Virginie , Jones Laura , Mitra Shreya , Livingstone Julie M. , Campbell Shirley , Hallett Michael , Mills Gordon B. , Park Morag , Chodosh Lewis , Strathdee Douglas , Norman Jim C. , Muller William J.
Published: April 2023

The Supplemental Figure 3 contains additionnal and key data sets to supplement the Figure 4. Briefly, we used the FIP1C-proficient and -deficient ErbB2/neuNDL cell lines to confirm the in vivo data related to cell proliferation analysis as presented at Figure 4. The Supplemental Figure 3 indicates that overexpression of FIP1C significantly decrease Ki67 levels and Cyclin-dependent inhibitors such as p21/CIP1 and p16/INK4A.
Supplementary Figures 1 through 5 from Systemic DC Activation Modulates the Tumor Microenvironment and Shapes the Long-Lived Tumor-Specific Memory Mediated by CD8+ T Cells
Authors: Shimizu Kanako , Yamasaki Satoru , Shinga Jun , Sato Yusuke , Watanabe Takashi , Ohara Osamu , Kuzushima Kiyotaka , Yagita Hideo , Komuro Yoshiko , Asakura Miki , Fujii Shin-ichiro
Published: April 2023

Figure S1. Characterization of aAVC-OVA Figure S2. Analysis of T cells in spleen and TIL after immunization of tumor-bearing mice with aAVC-OVA Figure S3. Phagocytosis and maturation of splenic dendritic cells after administration of aAVCs Figure S4. Confirmation of depletion of the XCR1+ subset of DCs in DT-treated XCR1-DTR-venus mice. Figure S5. Induction of an OVA-specific T cell response by aAVC-OVA in a dose-dependent manner
Supplementary Figure 4 from Stress Chaperone Mortalin Contributes to Epithelial-to-Mesenchymal Transition and Cancer Metastasis
Authors: Na Youjin , Kaul Sunil C. , Ryu Jihoon , Lee Jung-Sun , Ahn Hyo Min , Kaul Zeenia , Kalra Rajkumar S. , Li Ling , Widodo Nashi , Yun Chae-Ok , Wadhwa Renu
Published: April 2023

Correlation of mortalin expression with cell migration capacity in normal human fibroblasts.
Supplementary Figure 2 from A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors
Authors: Liu Xiaojun , Ranganathan Raghuveer , Jiang Shuguang , Fang Chongyun , Sun Jing , Kim Soyeon , Newick Kheng , Lo Albert , June Carl H. , Zhao Yangbing , Moon Edmund K.
Published: April 2023

Schematic of PD1CD28 switch receptor, mutated PD1CD28 switch receptor, and tailless/signal-dead PD1.
Supplementary Table S4 from Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization
Authors: Li Dan , Wang Xiaojing , Mei Hong , Fang Erhu , Ye Lin , Song Huajie , Yang Feng , Li Huanhuan , Huang Kai , Zheng Liduan , Tong Qiangsong
Published: April 2023

Table S4 shows the mass spectrometry analysis of protein pulled down by biotin-labeled pancEts-1 or hnRNPK antibody in BE(2)-C cells
Supplementary Table S3 from Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization
Authors: Li Dan , Wang Xiaojing , Mei Hong , Fang Erhu , Ye Lin , Song Huajie , Yang Feng , Li Huanhuan , Huang Kai , Zheng Liduan , Tong Qiangsong
Published: April 2023

Table S3 shows the pancEts-1 and hnRNPK transcript levels in 42 NB patients
Supplementary Table S2 from Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization
Authors: Li Dan , Wang Xiaojing , Mei Hong , Fang Erhu , Ye Lin , Song Huajie , Yang Feng , Li Huanhuan , Huang Kai , Zheng Liduan , Tong Qiangsong
Published: April 2023

Table S2 shows oligonucleotide sets used for constructs and short hairpin RNAs
Supplemental Table S4 from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Authors: Tian Yuan , Wong Vincent W.S. , Wong Grace L.H. , Yang Weiqin , Sun Hanyong , Shen Jiayun , Tong Joanna H.M. , Go Minnie Y.Y. , Cheung Yue S. , Lai Paul B.S. , Zhou Mingyan , Xu Gang , Huang Tim H.M. , Yu Jun , To Ka F. , Cheng Alfred S.L. , Chan Henry L.Y.
Published: April 2023

The antibodies used in this study.
Supplementary Data from Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer
Authors: Moughon Diana L. , He Huanhuan , Schokrpur Shiruyeh , Jiang Ziyue Karen , Yaqoob Madeeha , David John , Lin Crystal , Iruela-Arispe M. Luisa , Dorigo Oliver , Wu Lily
Published: April 2023

Supplementary figure legends and data text
Supplemental Materials and Methods from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Authors: Tian Yuan , Wong Vincent W.S. , Wong Grace L.H. , Yang Weiqin , Sun Hanyong , Shen Jiayun , Tong Joanna H.M. , Go Minnie Y.Y. , Cheung Yue S. , Lai Paul B.S. , Zhou Mingyan , Xu Gang , Huang Tim H.M. , Yu Jun , To Ka F. , Cheng Alfred S.L. , Chan Henry L.Y.
Published: April 2023

Description of additional methods and procedures used in the study.
Supplemental Figure S7 from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Authors: Tian Yuan , Wong Vincent W.S. , Wong Grace L.H. , Yang Weiqin , Sun Hanyong , Shen Jiayun , Tong Joanna H.M. , Go Minnie Y.Y. , Cheung Yue S. , Lai Paul B.S. , Zhou Mingyan , Xu Gang , Huang Tim H.M. , Yu Jun , To Ka F. , Cheng Alfred S.L. , Chan Henry L.Y.
Published: April 2023

HDAC8 acts in concert with EZH2 to epigenetically repress Wnt antagonists.
Supplemental Figure S5 from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Authors: Tian Yuan , Wong Vincent W.S. , Wong Grace L.H. , Yang Weiqin , Sun Hanyong , Shen Jiayun , Tong Joanna H.M. , Go Minnie Y.Y. , Cheung Yue S. , Lai Paul B.S. , Zhou Mingyan , Xu Gang , Huang Tim H.M. , Yu Jun , To Ka F. , Cheng Alfred S.L. , Chan Henry L.Y.
Published: April 2023

HDAC8 promotes growth and inhibits apoptosis of HCC cells.
Supplementay Tables from Infiltrating Macrophages Induce ERα Expression through an IL17A-mediated Epigenetic Mechanism to Sensitize Endometrial Cancer Cells to Estrogen
Authors: Ning Chengcheng , Xie Bingying , Zhang Lin , Li Chunsheng , Shan Weiwei , Yang Bingyi , Luo Xuezhen , Gu Chao , He Qizhi , Jin Hongyan , Chen Xiaojun , Zhang Zhenbo , Feng Youji
Published: April 2023

1. Basic characteristics of endometrial hyperplasia and EC patients. Supplementary Table 2. Basic information of clinical samples for Immunohistochemistry. Supplementary Table 3. Primers used.
Supplemental Figure S3 from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Authors: Tian Yuan , Wong Vincent W.S. , Wong Grace L.H. , Yang Weiqin , Sun Hanyong , Shen Jiayun , Tong Joanna H.M. , Go Minnie Y.Y. , Cheung Yue S. , Lai Paul B.S. , Zhou Mingyan , Xu Gang , Huang Tim H.M. , Yu Jun , To Ka F. , Cheng Alfred S.L. , Chan Henry L.Y.
Published: April 2023

HDAC8 promotes insulin resistance.
Supplemental Figure S2 from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma
Authors: Tian Yuan , Wong Vincent W.S. , Wong Grace L.H. , Yang Weiqin , Sun Hanyong , Shen Jiayun , Tong Joanna H.M. , Go Minnie Y.Y. , Cheung Yue S. , Lai Paul B.S. , Zhou Mingyan , Xu Gang , Huang Tim H.M. , Yu Jun , To Ka F. , Cheng Alfred S.L. , Chan Henry L.Y.
Published: April 2023

HDAC8 is directly regulated by SREBP-1 in HCC cells.
Supplementary Figure 4 from Infiltrating Macrophages Induce ERα Expression through an IL17A-mediated Epigenetic Mechanism to Sensitize Endometrial Cancer Cells to Estrogen
Authors: Ning Chengcheng , Xie Bingying , Zhang Lin , Li Chunsheng , Shan Weiwei , Yang Bingyi , Luo Xuezhen , Gu Chao , He Qizhi , Jin Hongyan , Chen Xiaojun , Zhang Zhenbo , Feng Youji
Published: April 2023

IL-17 receptor antibody compromises the effect of IL-17A on ERα transcription up-regulation
Supplementary Figure 2 from Infiltrating Macrophages Induce ERα Expression through an IL17A-mediated Epigenetic Mechanism to Sensitize Endometrial Cancer Cells to Estrogen
Authors: Ning Chengcheng , Xie Bingying , Zhang Lin , Li Chunsheng , Shan Weiwei , Yang Bingyi , Luo Xuezhen , Gu Chao , He Qizhi , Jin Hongyan , Chen Xiaojun , Zhang Zhenbo , Feng Youji
Published: April 2023

Induction of CD68+CD163+ macrophages from THP-1 cells
Video S2 from In Vivo Visualization and Characterization of Epithelial–Mesenchymal Transition in Breast Tumors
Authors: Zhao Zhen , Zhu Xiaoping , Cui Kemi , Mancuso James , Federley Richard , Fischer Kari , Teng Gao-jun , Mittal Vivek , Gao Dingcheng , Zhao Hong , Wong Stephen T.C.
Published: April 2023

A representative video showing the Zâ€�stack IVM images of a 2mmâ€�diameter pure RFP+ cellinjected tumor in the wild type mouse. Sporadic GFP+ cells with cuboidal morphology were examined in the tumor.
Figure S7 from GADD45β Loss Ablates Innate Immunosuppression in Cancer
Authors: Verzella Daniela , Bennett Jason , Fischietti Mariafausta , Thotakura Anil K. , Recordati Camilla , Pasqualini Fabio , Capece Daria , Vecchiotti Davide , D'Andrea Daniel , Di Francesco Barbara , De Maglie Marcella , Begalli Federica , Tornatore Laura , Papa Salvatore , Lawrence Toby , Forbes Stuart J. , Sica Antonio , Alesse Edoardo , Zazzeroni Francesca , Franzoso Guido
Published: April 2023

Germline Transmission of the Gadd45bF Allele
Supplementary figure 1-3 from In Vivo Visualization and Characterization of Epithelial–Mesenchymal Transition in Breast Tumors
Authors: Zhao Zhen , Zhu Xiaoping , Cui Kemi , Mancuso James , Federley Richard , Fischer Kari , Teng Gao-jun , Mittal Vivek , Gao Dingcheng , Zhao Hong , Wong Stephen T.C.
Published: April 2023

Supplementary figure 1: Scheme of the imaging setup and representative in vivo images Supplementary figure 2: Representative in vivo images of GFP+ cells in middle and large tumors Supplementary figure 3: High expression of c-Met and Flt 1/4 correlate with metastasis-free survival in breast cancer patients
Figure S2 from GADD45β Loss Ablates Innate Immunosuppression in Cancer
Authors: Verzella Daniela , Bennett Jason , Fischietti Mariafausta , Thotakura Anil K. , Recordati Camilla , Pasqualini Fabio , Capece Daria , Vecchiotti Davide , D'Andrea Daniel , Di Francesco Barbara , De Maglie Marcella , Begalli Federica , Tornatore Laura , Papa Salvatore , Lawrence Toby , Forbes Stuart J. , Sica Antonio , Alesse Edoardo , Zazzeroni Francesca , Franzoso Guido
Published: April 2023

Increased TLS Formation, Macrophage Infiltration and Proinflammatory TAM Activation in HCCs from Gadd45b-/- Mice