bluuebunny/crossref_metadata_2025 huggingface dataset:
CLINIC-IMMUNOLOGICAL FEATURES OF CHRONIC RECURREN PURULENT INFECTIONS OF THE SKIN
Authors: Novikova I. A. , Gomoliako A. V. , Ustinova M. V. , Salivonchik A. P.
Published: February 2023

The analysis of clinic-laboratory parameters of 73 patients with chronic purulent inflammatory diseases of the skin during the remission of the basic disease was carried out. At 31,5 % of patients in the samples from the pharynx S.aureus was revealed in diagnostically significant amount. Also in such patients accompanying chronic infections significantly more often were marked (р = 0,022), relative amount of B-lymphocytes and concentration of IgA in blood were decreased. Changes in the immunorgamme had a versatile character and concerned mainly humoral immunity.
DETECTION OF RESISTANCE OF HELICOBACTER PYLORI TO CLARITHROMYCIN BY DNA-MARKERS
Authors: Voropaeva A. V.
Published: February 2023

The pattern of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used for the detection of resistance to clarithromycin H. pylori. During the examination of 125 patients with proved H. Pylori contamination the restriction analysis of 23S rRNA gene fragment of H. Pylori did not detect T2717C point mutation connected with the phenotype of low level of resistance to clarithromycin. The phenotype of high level of resistance to clarithromycin was detected only in 5,5 % of patients. Taking into account low indicators of phenotypic resistance, the conclusion that clarithromycin can be successfully used as a preparation of the first line of eradication therapy of H. Pylori in the Republic of Belarus has been made.
IMPORTANCE OF THE HUMAN ANATOMIC CONSTITUTION IN FORECASTING OF DEVELOPMENT OF DISEASES
Authors: Senko V. I. , Okolokulak E. S.
Published: February 2023

The literary review of the data confirming that for forecasting of various diseases at man, the complex estimation of its anthopometrical parameters is necessary, as one of the most valid methods of mass prescreening is presented in the article.
PECULIARITIES OF NEOPLASM MORBIDITY RATE AND MORTALITY RATE IN EAST AND SOUTH PRE-FRONTIER REGIONS OF THE REPUBLIC OF BELARUS
Authors: Glynskaya T. N. , Gulitskaya N. I.
Published: February 2023

High level of morbidity rate and mortality rate due to neoplasm is an important problem of public health in the Republic of Belarus. Accepting life style and environment as factors determining health status in the population, morbidity rate and mortality rate due to neoplasm in the East and South pre-frontier regions have been studied in dynamics for the first time with regard to some geographical peculiarities. The obtained results suggested the significant differentiation of neoplasm morbidity rate and mortality rate depending on the territory aspects. This requires purposeful approach for developing organizational measures to optimize the present situation.
FETAL GROWTH RETARDATION - CONTEMPORARY VISION OF THE PROBLEM (reference review)
Authors: Budjuchina O. A.
Published: February 2023

In article the review of modern representations about an intrauterine growth retardation syndrome. The comparative estimation of classifications and unification of a terminological designation of the pathology connected to slowed down development and insufficiency of a fetus, by change weight and growth parameters infants is resulted. Aspects of pathogenesis of placental insufficiency and intrauterine growth retardation are submitted.
CIRCULATION DINAMYCS OF SPECIFIC SERUM MARKERS OF HERPETIC (HSV, CMV) INFECTION ACTIVE REPLICATION IN POPULATION OF GOMEL REGION
Authors: Linkevitch E. Ye.
Published: February 2023

There was estimated infecting of Gomel Region population with Herpes Simplex Virus (HSV) and Cytomegalovirus (CMV). There was determined frequency of reactivation of above-mentioned infections during the calendar year. Determination of serum markers to HSV and CMV was carried out by means of quantitative method of hard-phase Immuno-Enzyme-Analysis (IEA) on test-systems of «Equipar-SRL-Diagnostici» firm. Blood serums of 551 people were subjected to one-moment analysis. 106 donors of blood plasma at the age of 20-49 years old were taken for the observation to determine HSV and CMV infection. In the process of the investigation there was determined that the level of HSV and CMV infecting appeared to be 96,4 and 92,4 % relatively. 30,2 % of the examined people were in the state of active HSV infection, 16,5 % - in the state of active CMV infection. Frequent HSV infection reactivation during the year was revealed in 73,6 ± 4,3 % people; CMV infection - in 32,1 ± 4,5 %. There was determined the seasonal relapse of herpetic infection with prevalence of infectious process activation during winter-spring time.
HYGIENIC REGULATION ACCIDENTALLY DANGEROUS CHEMICAL SUBSTANCES IN DRINKING WATER AS METHODOLOGICAL PROBLEM
Authors: Filanyuk V. A. , Shevlyakov V. V.
Published: February 2023

Consideration of questions related to the hygienic regulation of accidentally dangerous substances is very important not only from the point of view of the real possibility of development of technogenic catastrophes at the chemical industries enterprises with potential possibility to contaminate the sources of logistic and drinking water supply or drinking water storage, but from the scientific point of view also due to uncertainty of methodology problem of study toxic influence of such substances on human body. To solve the questions on methodological justification of approaches, criteria and principles of hygienic regulations of accidentally dangerous substances at the present stage of development of hygiene as a science is possible in the framework of tasks of scientific technical programmes.
FORECASTING OF INTERFERON THERAPY EFFICIENCY IN PATIENTS WITH CHRONIC HEPATITIS C
Authors: Krasavtsev E. L.
Published: February 2023

The virologic response evaluating in patients with chronic hepatitis C with various histologic index of a stage of chronisation, detection of antibodies to hepatitis C virus (HCV) NS5 protein and antibodies to HCV of IgM class, cytokines IL-2, IL-4, IL-1β, TNF-α levels in blood was carried out in various terms of interferon therapy. The prognostic value of moderate degree of fibrosis, absence of anti-NS5 and anti-HCV IgM, high levels of proinflammatory cytokine IFN-α for an interferon therapy efficiency estimation was shown.
HYPERBARIC OXYGENATION OF ACUTE CORONARY SYNDROME: MODERN PREREQUISITES (references review)
Authors: Salivonchik D. P.
Published: February 2023

The conclusive medicine base of hyperbaric oxygenation use in The case of acute cardiology pathology was introduce in this review.
THE LETHAL OUTCOME PROBABILITY FORECASTING AT HIV-INFECTED PATIENTS IN VIEW OF ANTIRETROVIRAL THERAPY
Authors: Kozorez E. I. , Zhavoronok S. V. , Mitsura V. M. , Krasavtsev E. L.
Published: February 2023

The probability of a lethal outcome within 12 months in 331 HIV-infected of the patients accepting antiretroviral therapy (ART) is defined. With the help of regression model were chosen five parameters which influence on risk of a lethal outcome is proved: sex, disease stage, CD4 cells level, haemoglobin level, presence of the diagnosed tuberculosis. According to the developed model probabilities of death in 3, 6, 9 and 12 months from the beginning of ART have been defined.
FUNCTIONAL STATE INDICES OF FOOTBALL PLAYERS FROM DIFFERENT AGES, OBTAINED TESTING WITH «OMEGA-S» EQUIPMENT
Authors: Pitkevich Y. .
Published: February 2023

Functional State Indices of football players from various age groups were computed, based on measurements performed with the «Omega-S» testing equipment. The majority were rated as «excellent» and «good». The proportion of «excellent» and «good» indices was highest in 16-25 age old group. High vegetative nervous system indices indicate greater capacity for emotional adjustment in more experienced football players.
PROGNOSTIC SIGNIFICANCE OF EXPRESSION OF CYCLINES B1 AND D1 IN CASE OF OVARIAN CARCINOMA
Authors: Shulga A. V. , Basinski V. A. , Savicki S. E.
Published: February 2023

Cyclins are a family of regulatory proteins that play a key role in controlling the cell cycle. Abnormalities of cell cycle regulators, including cyclins and cyclin dependent kinases, have been reported in various malignant tumors. Expression of cyclin B1, D1 was investigated with immunohistochemical method in 69 cases of primary ovarian carcinoma. Five-year survival and degree of differentiation have been found to depend on сyclins D1, В1.
MECHANICAL SKIN QUALITIES: CONTRACTILITY AND TENSILITY, THEIR CORRELATION, HISTOLOGICAL BASIS AND THE POSSIBILITY OF FORECASTING
Authors: Kurek M. F. , Anichkin V. V. , Shilko S. V. , Doroshenko R. V.
Published: February 2023

Learning the process of changes in skin that occurs during plastic surgery is of great importance for the effective planning of plastic operations. According to biomechanics the human skin is a composite material with heterogeneous nonlinear anisotropic viscoelastic characteristics. This is associated with difficulties in building an effective model of soft tissues and skin. Most investigators consider dermis to be the determinative of mechanical properties of the full-thickness skin. And architectonics is the main reason of differences in mechanical behaviour of the skin. One of the methods of studying the skin properties is mechanical test, which is considered as functional biopsy, as its behavior is defined by its microstructural composition and organization. The aim of this study was to determine such features as contractility and tensile strength, their histological foundation and an opportunity to predict them. As we`ve found the features of interest in spite of being determined by the same microanatomical structures have a complicated nonlinear correlation and depend on different characteristics of connective tissue fibers.
MECHANIZMS OF APOPTOSIS IN CEREBRAL ISCHEMIA
Authors: Ugolnick T. S. , Chubukova T. N.
Published: February 2023

The article consists of the literary review, which summarized current data about mechanisms of apoptosis, in consequence of the developing cerebral ischemia.
SURGICAL INSTRUMENTS FOR EXPERIMENTAL RESEARCHES
Authors: Doroshkevich S. V. , Doroshkevich E. Yu.
Published: February 2023

New surgical instruments, created by the authors, for realization of operative operations on laboratory animals (rats) are introduced. The parameters of working parts of the instruments: wound dilator, cryosurgical tip, needle holder and pincers allow to optimize realization of experimental researches. The offered instruments are easily reproduced, that give an opportunity of their broad usage in experimental surgery.
THE DYNAMICS OF PROINFLAMMATORY CYTOKINES IN DIFFERENT VARIANTS OF ANTIBACTERIAL THERAPY OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS
Authors: Karazei E. A. , Davidovskaya E. I.
Published: February 2023

The dynamics (before and after treatment) of proinflammatory cytokines (interleukin-8 (IL-8) and tumor necrosis factor-α (TNF-α)) levels in serum and in bronchoalveolar fluid (BALF), of indices of BALF cytograms, of indices of respiratory function (RF), of bronchoscopic data in different variants of antinflammatory therapy of chronic obstructive pulmonary disease exacerbations (COPD) was studied in 60 patients. Statistically significant decline in percentages of neutrophils and in IL-8 and TNF-α - levels in serum and in BALF was revealed. It was considered, that the Indices of BALF cytograms and cytokine levels in BALF can be used in treatment efficacy monitoring. Clarithromycin is more effective in the reduction of activity of inflammatory process in COPD exacerbations.
NONSPECIFIC ANTIBODIES IN BLOOD SERUM IN HIV-POSITIVE PREGNANT WOMEN
Authors: Gromyko N. L. , Baranovskaya E. I. , Zhavoronok S. V. , Golubih N. M.
Published: February 2023

We studied serum immunoglobulin A,M,G levels in 68 HIV-positive, 36 HIV-negative pregnant women and 31 HIV-positive non-pregnant women by enzyme linked immunosorbent assay. HIV-infection has negative influence on humoral immunity during pregnancy.
THE ANALYSIS OF PARAMETERS ECHOCARDIOGAPHY AT PATIENTS WITH CORONARY HEART DISEASE DEPENDING ON BIOELECTRET PROPERTIES OF BLOOD
Authors: Vechersky G. A. , Nikolaeva N. V.
Published: February 2023

The given changes of structurally functional parameters of a myocardium left ventricular in clinical groups of patients with chronic ischemic illness of heart are analysed. The analysis has allowed to reveal statistically significant distinctions on the majority of the parameters describing structurally functional reorganization of a myocardium left ventricular at patients with chronic ischemic illness of heart. The given researches have shown presence of dependence between size of a residual charge and parameters echocardiography in clinical groups of patients with chronic ischemic illness of heart. The assumption is confirmed, that change bioelectret properties of blood can be considered, how a nonspecific marker of a degree of pathological changes of cardiovascular system, including, and in conditions of structurally functional reorganization of a myocardium.
OTOMYCOSIS OF THE EXTERNAL AND THE MIDDLE EAR: CLINIC, DIAGNOSTICS AND TREATMENTS (REFERENCES REVIEW)
Authors: Yadchenko E. S. , Sitnicov V. P. , Schlyaga I. D.
Published: February 2023

In article the review of modern representations dedicated problems etyopathogenesis, clinic, diagnostics and treatment mycotic affection external and middle ear.
WARTS IN CHILDREN: CLINICAL AND THERAPEUTIC FEATURES
Authors: Levonchuk E. A. , Yahnitsky G. G.
Published: February 2023

In the article there are main clinical forms of warts: common, flat, plantar. Attention is paid on the features of the clinical course of warts in children. The survey of the basic methods of wart therapy has been presented, also their merits and demerits. The personal experience of the treatment for warts in children with the use of groprinosyne as antiviral and immunomodulatory medicine was given. The decrease of relapse likelihood in 2,5 times less was indicated.
EXPERIENCE OF THE APPLICATION OF SPIRITUOUS SOLUTION OF RESORCYNE FOR THE TREATMENT OF POINTED CONDYLOMAS
Authors: Hilkevich N. D.
Published: February 2023

The results of the treatment of pointed candylomas in 34 men by means of exterior applications of 33 % spirituous solution of resorcyne on the lesion focus have been presented. The suggested method of treatment was marked by high effectiveness as well as good tolerance and possibility of application by the patients themselves at home.
FIRST EXPERIENCE OF THE DETECTION of the HPV Е6/Е7 ONCOPROTEINS EXPRESSION IN a PROPHYLACTIC EXAMINATION
Authors: Kostevich G. V. , Kosenko I. A.
Published: February 2023

In the article there are investigation results of the HPV 16 Е6/Е7 oncoproteins, detected by means of colposcopy in the pathological samples of cervical epithelium, taken from 82 patients during prophylactic examinations. It has been ascertained, that of the examined women, 39,0 % are HPV positive, and 78,1 % reveal HPV in the clinically significant concentration, the HPV 16 predominates in each second. The HPV 16 Е6/Е7 oncoproteins expression was detected in 66,7 ± 12,2 % cases, which made up 12,2 % of the whole investigation group. In connection with this, the conclusions have been made, that it is reasonable to use colposcopy with the subsequent HPV investigation (HPV genotyping, evaluation of viral load level, detection of oncoproteins expression) during prophylactic examinations for diagnostics of subclinical forms of the HPV infection of the cervix. As each tenth of practically healthy women, having colposcopic features of the viral lesion of the cervical epithelium, due to the presence of the HPV 16 and synthesis of viral proteins in the cervical epithelium cells, possessing carcinogenic activity, is in the high risk group of the development of cervical cancer. Key words: prophylactic examination, HPV, Е6/Е7 oncoproteins.
Estado del arte del estudio de los sistemas agroalimentarios localizados en México
Authors: Sánchez-Vásquez Velia , Cesín-Vargas José Alfredo
Published: February 2023

Este trabajo presenta información reciente de investigaciones nacionales e internacionales, sobre los Sistemas Agroalimentarios Localizados (SIAL), modelo que surgió como alternativa para valorizar los recursos de zonas rurales, se analizaron los enfoques de estudio, los objetivos y los resultados obtenidos en cada aportación, con la finalidad de encontrar coincidencias y diferencias conceptuales que permitirán al investigador conocer los avances logrados en su estudio y aplicación. Entre los elementos destacados se encontraron la valorización territorial, la acción colectiva, el patrimonio cultural, el respeto al medio ambiente, así como la inclusión de mujeres y jóvenes. A pesar de que se ha avanzado considerablemente en el análisis de la activación de la metodología de los SIAL en diferentes territorios, se observó que la intervención de las instituciones gubernamentales, como respaldo a las acciones locales y a una cultura de consumo responsable, fueron factores clave para el éxito de la implementación. No así el caso de México, en donde no ha logrado permear en las políticas gubernamentales, dejando una oportunidad importante para reforzar los estudios previos y generar nuevas investigaciones que busquen la apertura de espacios institucionales gubernamentales que permitan formar las redes necesarias que den el impulso requerido para beneficio de los productores.
Políticas públicas de desarrollo rural en Brasil y Chile
Authors: Deponti Cidonea Machado , Lima da Silveira Rogério Leandro , Tirelli Cláudia , Gac-Jiménez Daniella , Thezá-Manriquez Marcel
Published: February 2023

Este artículo analiza el diseño institucional (actores involucrados, estructura organizacional, formas de financiamiento, objetivos, público objetivo) y los efectos de la implementación de dos políticas de desarrollo rural dirigidas a la agricultura familiar (AF) en Brasil y Chile: PRONAF y PRODESAL, a partir de un análisis comparativo. El estudio se basó en una revisión bibliográfica y en el análisis de documentos oficiales. En relación con el PRONAF verificamos que hubo una concentración de recursos en los estados de la Región Sur de Brasil desde el inicio de su implementación, lo que impidió un cambio efectivo en el modelo de desarrollo agrícola vigente en el país. En el caso del PRODESAL, observamos la necesidad de realizar evaluaciones de impacto, ya que el programa generó esquemas de dependencia en relación con sus usuarios. En la comparación observamos que presentan más similitudes que diferencias, siendo ambas indispensables en sus países para la valorización de la AP y la reproducción de las condiciones materiales y simbólicas en el medio rural.
Madres trabajadoras: entre el trabajo productivo y reproductivo
Authors: Vásquez Gabriela
Published: February 2023

Las mujeres han sido históricamente las encargadas de la reproducción familiar. Sin embargo, este trabajo ha sido infravalorado e incluso considerado denigrante. El objetivo del presente ensayo es discutir acerca de los principales aportes feministas del siglo XX y XXI al trabajo productivo y reproductivo de las mujeres.
Se realizó una revisión documental sobre feminismo, economía feminista, división sexual del trabajo y maternidades para argumentar cómo el patriarcado ha relegado a las mujeres al ámbito privado exigiendo de ellas la reproducción del hogar y dificultando su realización personal y profesional con igualdad respecto a los hombres.
Los estudios feministas han visibilizado, entre otras situaciones, la doble jornada de las madres trabajadoras y la importancia del trabajo reproductivo. Asimismo, ha señalado la necesidad de que los hombres, el Estado y las empresas se responsabilicen también del trabajo doméstico y de cuidados que posibilita el funcionamiento del sistema económico tal como lo conocemos.
Aspectos sociales y económicos de la microindustria familiar ladrillera en la zona periurbana de Puebla, México.
Authors: Díaz de Mora Yajaira Violeta , Ramírez Valverde Benito , Estrella Chulim Nestor , Bustamante González Ángel , Juárez Sánchez José Pedro , Vaquera Huerta Humberto
Published: February 2023

Las transformaciones históricas del espacio rural han modificado profundamente las funciones de las localidades ladrilleras ubicadas en la zona periurbana de Puebla, México. El objetivo del estudio fue analizar el desarrollo de la actividad ladrillera y las características sociodemográficas y económicas de la familia ladrillera de San Pedro Cholula, en Puebla. Se realizó un estudio de corte transversal, mediante un muestreo estadístico con un cuestionario semiestructurado y una muestra de 73 productores de ladrillo. Los resultados muestran que la actividad ladrillera es importante para la economía familiar debido a la utilización de mayor cantidad de mano de obra familiar, la demanda del sector construcción, la poca tierra disponible y la baja rentabilidad de la actividad agrícola. El aporte del estudio fue abordar la diversidad laboral que rompe con la idea de lo rural ligado exclusivamente a lo agrícola, mediante la pluriactividad.
Capital social y acción colectiva en el cultivo de palma de aceite en la costa de Chiapas. Estudio de OleopalMex.
Authors: Valdiviezo Ocampo Guillermo S. , Trejo-Sánchez Enrique de Jesús
Published: February 2023

La expansión del cultivo de palma de aceite en México ha generado un conjunto de procesos, como la menor participación de los pequeños productores que se encuentran sujetos a las condiciones que establecen las empresas extractoras, la acumulación de tierras por parte de las grandes empresas, la apropiación de la mayor parte de los excedentes por empresas internacionales, y los efectos ambientales negativos. El objetivo de este trabajo radica en analizar los procesos de generación de capital social y acción colectiva que han emprendido los productores de la costa de Chiapas para construir la empresa social Oleopalmex con el fin de responder a las condiciones que imponen las empresas extractoras en la región. Se encuentra, que las empresas integrantes de Oleopalmex han desarrollado diferentes niveles de capital social y acción colectiva, pero que las empresas con menor nivel recurren a las de mayor nivel para subsanar sus problemas de producción y gestión. En este trabajo se demuestra que los productores de palma con base en el aprovechamiento del capital social y la acción colectiva han logrado construir una empresa social que les permite revertir parcialmente las sanciones impuestas por las empresas extractoras de aceite y, les posibilita participar de una mayor parte del valor generado en el sistema de palma.
Strategi Pemerintah Desa Dalam Pengembangan Potensi Kampung Wisata Desa Gunung Malelo Kecamatan Koto Kampar Hulu Tahun 2020
Authors: Hartati Seri , Anugerah Muhammad Fajar , Yasri Mhd. Tegar
Published: February 2023

Masyarakat di Desa Gunung Malelo sebagai salah satu Desa dengan potensi wisata tinggi, harus mampu bergerak dalam peningkatan menuju kampung wisata. Penelitian ini bertujuan untuk melihat dan menganalisis mengenai strategi pemerintah dalam pengembangan potensi kampung wisata Desa Gunung Malelo Kecamatan Koto Kampar Hulu, Kabupaten Kampar, Riau. Penelitian ini menggunakan pendekatan kualitatif dan jenis penelitian analisis deskriptif. Sumber data diambil dari hasil wawancara, observasi, dokumentasi dan buku-buku terkait. Teori yang digunakan adalah teori 4P (Product, Price, Place, Promotion). Hasil penelitian ini adalah Desa Gunung Malelo memiliki delapan unggulan wisata (Product), seperti wisata religi, wahana air, wahana keluarga dan juga kuliner. Price (harga) wisata Gunung Malelo adalah wisata yang ramah lingkungan, mudah, murah dan nyaman. Place dalam strategi pemerintah terhadap peningkatan potensi perkembangan lokasi wisata Desa Gunung Malelo adalah dengan mengadakan sarana dan prasarana guna kemajuan wisata dalam pembenahan dan juga membangun solidaritas. Dan strategi (promotion) yang dilakukan oleh Desa Gunung Malelo dalam promosi menggunakan media cetak dan media sosial.
Analisis Pengalihan Kewenangan Pengelolaan Pendidikan Menengah dari Pemerintah Kabupaten/Kota ke Pemerintah Provinsi di Kabupaten Maros
Authors: Faisal Andi Fahri
Published: February 2023

Tujuan penelitian ini adalah untuk mengetahui dan menggambarkan pelaksanaan pengalihan pengelolaan pendidikan menengah dari kabupaten/kota di Kabupaten Maros, serta hambatan dan tantangan dalam pelaksanaan pengalihan kewenangan pengelolaan pendidikan menengah di kabupaten Maros. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif, teknik pengumpulan data yang digunakan adalah observasi dan wawancara langsung serta dianalisis secara kualitatif. Hasil penelitian menunjukkan bahwa : (1) beralihnya status kepegawaian guru dan tenaga pendidikan menjadi pegawai pemerintah provinsi Sulawesi Selatan, Guru dan tenaga pendidikan merasakan adanya keterlambatan dalam transfer gaji dan tunjangan guru, pengurusan administrasi yang jauh, dan bertambahnya penghasilan guru honorer. Pendanaan pendidikan menengah khususnya dana BOS menuai keterlambatan dalam pencairannya, serta kepala sekolah tidak leluasa mencari sumber bantuan lain. (2) Hambatan dalam pelaksanaan pengalihan kewenangan pengelolaan pendidikan menengah di Kabupaten Maros adalah penyebaran kebutuhan guru yang tidak merata, adanya birokrasi yang rumit, dan pengelolaan aset yang belum tuntas di Kabupaten Maros. Sedangkan, tantangannya adalah nuansa psikologisnya untuk bersaing secara global, wilayah Sulawesi Selatan yang luas, dan peningkatan kompetensi aparatur.
Analisis Hukum Asuransi Kendaraan Bermotor Menurut Kitab Undang-Undang Hukum Dagang
Authors: Sagita Rhayza Hayuarsi Sekar Sagita
Published: February 2023

Pengaturan asuransi komersial di Indonesia diatur dalam KUHPerdata dimana asuransi sebagai sebuah perjanjian yang tunduk pada perjanjian pada umumnya sebagai acuan pembuatan perjanjian asuransi, KUHD dalam Undang-Undang Nomor 2 Tahun 1992 yang mengatur asuransi sebagai sebuah bisnis yang mengatur perilaku mereka yang menjalankan usaha perasuransian. Penelitian ini menggunakan pendekatan kualitatif dengan Teknik deskriptif dalam menganalisis hukum asuransi kendaraan bermotor menurut Kitab Undang-Undang Hukum Dagang. Hasil analisis menunjukkan bahwa usaha asuransi sebagai sebuah lembaga yang menghimpun dana milik dari masyarakat usaha asuransi sebagai sebuah lembaga yang menghimpun dana milik dari masyarakat yang menjalankan usahanya dengan berpegang pada prinsip usaha yang sehat dan bertanggung jawab yang tunduk pada pengaturan yang dilakukan pemerintah, serta pertanggungjawaban dapat dilakukan dengan diawali pada terbitnya polis asuransi yang telah disepakati secara bersama oleh tertanggung dan penanggung serta telah dilakukannya pembayaran premi oleh tertanggung kepada pihak penanggung sehingga dengan demikian terjadi peralihan resiko serta timbul hak dan kewajiban diantara keduanya.
Pengaruh Kemasan, Harga dan Promosi Terhadap Keputusan Pembelian pada Produk Roti Mantao (Sinar Terang) Kota Madya Parepare
Authors: Sampara Nirwana
Published: February 2023

Penelitian ini bertujuan untuk mengetahui pengaruh kemasan, harga dan promosi terhadap keputusan pembelian secara parsial dan simultan pada Produk Roti Mantao di Kota Parepare. Penelitian Ini dilakukan di Sinar Terang Kota Parepare dengan menggunakan analisis deskriptif kuantitatif. Metode yang digunakan yaitu metode kuantitatif dengan teknik pengumpulan data yang digunakan yaitu kuesioner, observasi dan studi pustaka, kuesioner dibagikan kepada konsumen Roti Mantao yang telah melakukan pembelian, adapun jumlah sampel sebanyak 200 orang, teknik analisis data yang digunakan yaitu analisis deskriptif, analisis regresi linear berganda, uji validasi dan reabilitas, metode asumsi analisis regresi dan penguji hipotesis. Kemasan, harga dan promosi yang digunakan pada produk Roti Mantao ini sudah baik sehingga dapat berkembang sampai saat ini. Berdasarkan hasil pengujian diketahui bahwa terdapat pengaruh secara positif dan signifikan kemasan, harga dan promosi terhadap keputusan pembelian, yakni sebesar 54,1 %, Hasil penelitian ini menunjukkan bahwa kemasan, harga dan promosi berpengaruh secara parsial dan simultan terhadap keputusan pembelian.
Analisis Tindak Pidana Skimming Oleh Kepolisian Daerah Sulawesi Selatan
Authors: Mappanyukki Andi Tanwir
Published: February 2023

Tujuan penelitian ini untuk mengetahui cara tindak pidana skimming Polda Sulawesi Selatan. Disamping untuk mengetahui upaya penyelamatan dan pencegahan kejahatan skimming yang dapat dituntutaskan melalui kepolisian. Manfaat dari penelitian ini diharapkan dapat menjadi referensi bagi penelitian selanjutnya, khususnya dalam upaya penanggulang dan pencegahan kejahatan skimming oleh kepolisian. Dan dapat dijadikan sebagai bahan menyelesaikan masalah-masalah kejahatan yang terjadi di masyarakat secara khusus penanggulang dan pecegahan kejahatan skimming. Teknik Pengumpulan data dalam penelitian ini menggunakan metode wawancara yang dilakukan dengan cara mengadakan tanya jawab secara langsung kepada pihak yang terkait dan dengan metode kepustakaan  yaitu teknik pengumpulan data dengan cara menganalisis dan mengkaji berbagai literatur yang berlaku dan sekaligus dikatkan dengan objek kajian, kemudian data yang telah dikumpulkan, baik data primer maupun data sekunder akan disusun dengan menggunakan analisis kualitatif dan kuantitatif, kemudian disajikan dalam bentuk deskriptif. Dari hasil penelitian ini penulis menemukan bentuk kejahatan skimming sesuai dengan data yang diperoleh dari 3 (tiga) Instansi penegak hukum yaitu Kepolisian Resort Sinjai Sulawesi Selatan, Kejaksaan Negeri Sinjai, dan Pengadilan Negeri Sinjai, sehingga penulis dapat menyimpulkan bahwa kejahatan skimming yang terjadi di Kabupaten Sinjai dari tahun 2018 sampai tahun 2020 mengalami peningkatan.
EFFECTS OF STRENGTH-BASED PARENTING ON ADOLESCENT’S RESILIENCE AND SELF-ESTEEM IN FAMILIES USING TALENTS MAPPING
Authors: Ningrum Diah , Supriyadi  , Utami Fitria Budi
Published: February 2023

Today's teens face challenges more than previous generations. The use of information and technology are mentioned as among the causes of problems for teenagers in Indonesia, such as; pornography, promiscuity, premarital sex, and low motivation to study. A positive parenting is needed to help adolescents build their resilience and self-esteem to deal with obstacles in their life. Previous research on parenting styles showed that parents who used strength-based parenting helped children to develop coping skills and increased self-esteem in teenagers. Strength-based parenting is used to identify and encourage teens to recognize and use their strengths in every aspect of their life. Thus, the current study was conducted to see this parental pattern's contribution to adolescents' resilience and self-esteem. The study was held on teenagers aged 11-18 from a family using Talents Mapping in Indonesia. Sixty responses were taken by using the Strength-Based Parenting Scale, Child Youth Resilience Measure-Revised, and Rosenberg Self-Esteem Scale. Data is analysed using a regression test. The findings showed that the effects of strength-based parenting on a teenager's self-esteem are positive and significant. It was also found that resilience is positively related to youth's self-esteem. Furthermore, strength-based parenting and resilience are simultaneously positive and significant on teenagers' self-esteem, as 10.4%.
Lumasiran (Oxlumo)
Authors: CADTH
Published: February 2023

CADTH recommends that Oxlumo be reimbursed by public drug plans for the treatment of primary hyperoxaluria type 1 (PH1) to lower urinary oxalate levels in pediatric and adult patients if certain conditions are met.

Oxlumo should only be covered to treat those with a genetically confirmed diagnosis of PH1 and whose urine oxalate excretion is not normalized with standard of care therapy (including 3 to 6 months of vitamin B6).

Oxlumo should only be reimbursed if its cost is reduced and it is initially prescribed by a nephrologist or metabolic diseases specialist experienced in the diagnosis and management of PH1.
Guselkumab (Tremfya)
Authors: CADTH
Published: February 2023

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.

The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.

This review assesses guselkumab (Tremfya) 100 mg/mL in a 1 mL pre-filled syringe or patient-controlled injector.

Indication: For the treatment of adult patients with active psoriatic arthritis. Guselkumab can be used alone or in combination with a conventional disease-modifying antirheumatic drug (DMARD) (e.g., methotrexate).
Mepolizumab (Nucala)
Authors: CADTH
Published: February 2023

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.

The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.

This review assesses mepolizumab (Nucala), 100 mg/mL for subcutaneous injection.

Indication: As add-on maintenance treatment with intranasal corticosteroids in adult patients with severe chronic rhinosinusitis with nasal polyps inadequately controlled by intranasal corticosteroids alone.
PRISÃO E ENVELHECIMENTO ETÁRIO NO BRASIL
Authors: Lourenço Luciana Leão da Fonseca , Capeletti Filipe , Moreira Suelen , Albuquerque Amanda Fonseca de , Lemões Andria Klug , Gasque Laerte de Azevedo
Published: February 2023

O trabalho visa abordar o tratamento dado à pessoa idosa pelo Código Penal e Processual Penal Brasileiro, levando-se em consideração o aumento de pessoas na faixa etária de 60 anos ou mais no país e o crescimento exponencial da população carcerária no Estado do Rio Grande do Sul, em análise da obra “Vulnerabilidade Etária: Idosos e Cárcere no Brasil” (GHIGGI, 2020).
OBJETOS DIGITAIS DE APRENDIZAGEM: UTENSÍLIOS QUE PODEM AUXILIAR OS DOCENTES E DISCENTES EM SEU COTIDIANO ESCOLAR
Authors: Melo Robson da Silva
Published: February 2023

Este trabalho de pesquisa tem como objetivo geral debater e apontar os principais objetos digitais de aprendizagens que são suporte de ensino nas escolas brasileiras. Partindo disso, compreenderemos a necessidade urgente de se levar as escolas públicas do Brasil, objetos digitais de aprendizagem. Para tanto, trouxemos autores, como Andreia Inamorato dos Santos (2012); Juliana Cristina Braga (2016) e Liane Margarida Rockenbach Tarouco, os quais verbalizaram a respeito dos recursos e ferramentas digitais em sala de aula; páginas na web: Sai digital; Digital House e Escola digital. Além de periódicos, dissertações e monografias de diversas universidades do Brasil, como a UNESP (2012); UFPR (2022); UEG (2016) e UFABC (2015).  Diante a realização dessa pesquisa, pudemos encontrar uma gama de materiais que podem levar aos professores e alunos da rede pública uma verdadeira revolução educacional. Partindo da concepção que os objetos digitais de aprendizagens são a ponte para essa afirmativa.
BOAS PRÁTICAS NO CUIDADO AO DOENTE CRÍTICO SUBMETIDO A OXIGENOTERAPIA DE ALTO FLUXO POR CÂNULA NASAL
Authors: Cordeiro Daniel , Santiago Dulce , Pires Isabel
Published: February 2023

Introdução: O recurso à oxigenoterapia de alto fluxo por cânula nasal no cuidado ao doente crítico adulto tem sofrido um crescimento exponencial. Os estudos desenvolvidos atestam a sua eficácia num leque cada vez mais diversificado de situações. Os benefícios fisiológicos e o conforto proporcionado tornam esta terapia uma forte alternativa à ventilação mecânica não invasiva. As práticas adotadas pelos profissionais podem influenciar o sucesso da terapia e o outcome do doente. Objetivo: Mapear a evidência científica disponível acerca das boas práticas a adotar no cuidado ao doente crítico submetido a oxigenoterapia de alto fluxo por cânula nasal. Metodologia: Foi efetuada uma revisão scoping de acordo com as orientações do Joanna Briggs Institute. A pesquisa foi efetuada na plataforma EBSCOhost©, na base de informações médicas UpToDate®, em revistas e jornais da especialidade, com limitação temporal para publicação dos estudos entre os anos de 2018 e 2022. A seleção teve por base a aplicação de critérios de inclusão e exclusão tendo sido selecionado um total de 7 artigos. Resultados: Os resultados obtidos remetem para a utilização da oxigenoterapia de alto fluxo em situações como: insuficiência respiratória aguda com hipoxemia; nas pausas da ventilação mecânica não invasiva; no pós-operatório ou no doente não cirúrgico com risco baixo/moderado de falha na extubação. O sucesso/insucesso da terapia é fortemente relacionado com a formação/experiência dos profissionais, com os valores de frequência respiratória e com os parâmetros de oxigenação/ventilação no início da terapia. A aplicação do índice de oxigenação respiratória, o controlo do balanço hídrico e o posicionamento precoce em decúbito ventral são ferramentas importantes na prevenção da falha. O fluxo de ar-oxigénio deve ser otimizado até ao máximo de 60L/min, ajustando-se de seguida a fração de oxigénio inspirado à saturação alvo para o doente. Valores mais baixos de temperatura do ar-oxigénio fornecido ao doente são promotores de maior conforto e tolerância. Conclusões: Este estudo permitiu uma ampliação do conhecimento sobre as boas práticas a adotar no cuidado ao doente crítico submetido a oxigenoterapia de alto fluxo por cânula nasal. É importante que se desenvolvam mais estudos e com maior nível de evidência, que sustentem a prática clínica dos profissionais na abordagem ao doente crítico submetido a oxigenoterapia de alto fluxo, e possibilitem a criação de recomendações/diretrizes de prática clínica.
KAPASSARINHO (DATURA STRAMONIUM) EFEITO E REAÇÕES CONTRAVERSAS
Authors: Kinhama Victorino Correia , Chimuco Marinela Sepalanga Vasco , Kapele Madalena Bumba Correia Kinhama
Published: February 2023

Articles The work was aimed at the bibliographical description of the Kapassarinho plant (Datura Stramonium), to understand its countervailing effects since there are few studies mentioned, its extracts are complex mixtures consisting of several chemical classes of natural products. Kapassarinho is a common name in Angola and is found in the interior of the country classified as a weed. To carry out this work we used the methodology of document review based on the review of books, scientific articles, magazines and other existing materials that addressed content of great contribution to this theme. There is no clarity about the origin of this plant, but if Africa is the cradle of humanity is where it originated and spread throughout the world, in Angola besides the medicinal aspects, young people use this plant as a drug. The seed of this species is highly effective against Colletotrichum gloeosporioides, although it is a host plant for many diseases and pests affecting crops of the Solanácea Family.
PROCESSO DE JURISDIÇÃO VOLUNTÁRIA: A NÃO HOMOLOGAÇÃO DE ACORDO EXTRAJUDICIAL PELO JUIZ DO TRABALHO E AS POSSÍVEIS CONSEQUÊNCIAS AO EMPREGADO
Authors: Oliveira Fransber Alves de , Pimentel Ana Patrícia Rodrigues
Published: February 2023

Este artigo tem por finalidade analisar os dispositivos 855-B a 855-E, Título X, Capítulo III-A, do Decreto-Lei Nº 5.452/1943, Consolidação das Leis do Trabalho, acrescentados pela Lei 13.467/2017, chamada de Reforma Trabalhista, que trata do Processo de Jurisdição Voluntária Para Homologação de Acordo Extrajudicial, com foco dirigido a discricionariedade jurisdicional em não homologação pelo juiz trabalhista dessa modalidade de acordo e as possíveis consequências dessa decisão. A problemática principal gira em torno da possibilidade da não homologação pelo juiz de acordo extrajudicial entre empregado e empregador, abordando as especificações dos artigos 855-B a 855-E, buscando identificar quais soluções, caso ocorra o indeferimento, problemas e possíveis falhas no processo de jurisdição voluntária. Tem como objetivo discutir as eventuais consequências da não homologação, ou homologação parcial do acordo extrajudicial pelo Juiz Trabalhista, analisando, a discricionariedade do julgador e a jurisdição contenciosa e voluntária, e diante das possíveis alternativas, apontar o caminho do devido processo legal. A metodologia da pesquisa tem caráter dedutivo, aplicando a pesquisa qualitativa, dentro da análise bibliográfica da legislação pátria vigente relacionada, Constituição Federal de 1988, Decreto-lei Nº 5.452/1943, Consolidação das Leis do Trabalho, Lei 13.467/2017, Reforma Trabalhista, jurisprudências, doutrinas, matérias jornalísticas, sites de notícias e artigos científicos. Concluiu-se por meio da pesquisa que não há prejuízo no processo de jurisdição voluntaria para os empregados, no entanto em respeito ao princípio da autonomia da vontade, sempre deve ser levado em consideração o princípio da proteção do trabalhador.
A OPRESSÃO DA PERFORMANCE FEMININA NO HOMEM GAY CONTEMPORÂNEO
Authors: Andrade Dayene Albuquerque , Pereira João Paulo Da Silva , Mendes Allyne Evellyn Freitas Gomes
Published: February 2023

Introdução: Performance de gênero como atravessamento da cultura no sujeito sendo a performance do feminino discriminada pelas regras de conduta social, heteronormatividade compulsória como fissura no processo de subjetivação do homem gay. Objetivo: analisar as manifestações de opressão da performance feminina no gay contemporâneo. Justificativa: Performar o feminino hoje é se colocar no lugar de inferior devido ao lugar que a mulher e a homossexualidade têm na sociedade hegêmonica, e esse não-lugar acarreta uma série de conflitos intrapsíquicos e extrapsíquicos no processo de subjetivação do homem gay. Métodos: Foi utilizada a revisão narrativa, e de interseccionalidade  através das quais busca-se aproximação de respostas para as questões levantadas, de forma crítica e pontual dos artigos localizados nas principais plataformas de pesquisa, dissertações e teses da BDTD, além de livros atualizados ou de autores clássicos e de referência na área. Tendo como destaque os autores Sigmund Freud; Judith Butler; Jonas Medeiros; Guilherme Libardi, Nilda Jacks, Michel Foucault, Simone de Beauvoir e Pierre de Bourdieu. Resultado: A internalização das condutas heteronormativas estão incutidas no registro simbólico de agrupamento de leis internas do homem gay e refletem diretamente na não aceitação da sua performance. Conclusão: A opressão da performance feminina no homem gay está diretamente ligada a esse desejo social de que o homem não pode demonstrar fragilidade, ou características humanas associadas à mulher e ao feminino.
AS PERSPECTIVAS DA ADVOCACIA TRABALHISTA PÓS-REFORMA DA LEI 13.467/2017
Authors: Pereira Monique Emanuela Andrade , Rodrigues Deivison de Castro
Published: February 2023

A Lei 13.467, comumente chamada Reforma Trabalhista, entrou em vigor em 13 de novembro de 2017, afetando o processo trabalhista e as relações individuais e coletivas de trabalho. Tal norma promoveu alterações substanciais, criando e revogando mais de cem artigos e parágrafos da CLT, flexibilizando uma série de direitos. O presente artigo objetiva apontar quais dessas mudanças implicaram em alterações na atuação da advocacia trabalhista. Por conseguinte, compreender o cenário da advocacia trabalhista no Brasil além de investigar os desafios do advogado nesse contexto, dispondo para isso revisão bibliográfica de livros, documentos, revistas especializadas, artigos científicos, dissertações, legislações e jurisprudências acerca do presente tema.
Enjeux de communication dans la multireprésentation cartographique reproductible
Authors: LAMBERT Nicolas , GIRAUD Timothée , YSEBAERT Ronan
Published: February 2023

Ce chapitre approfondit la communication cartographique à travers un exercice de multireprésentation cartographique. En conservant un même jeu de donnée de la population mondiale, le chapitre présente et discute une série de 13 cartes différentes afin d’illustrer en quoi la cartographie est avant tout une question de choix et de méthodes.
Géovisualisation et communication cartographique : style et interaction
Authors: CHRISTOPHE Sidonie
Published: February 2023

Ce chapitre revient sur les modalités et les enjeux des articulations entre géovisualisation et communication cartographique qui s’opèrent aujourd’hui. Cette contribution originale aborde les questions de styles cartographiques, de personnalisation et d’interaction homme-machine au centre des problématiques de communication cartographique contemporaines.
Les coûts de production de l’électricité nucléaire
Authors: DEVEZEAUX DE LAVERGNE Jean-Guy
Published: February 2023

Ce chapitre fournit une vue d’ensemble des coûts de production de l’électricité nucléaire observés concrètement dans plusieurs pays disposant d’un parc nucléaire (France, Royaume-Uni, États-Unis), aussi bien pour les réacteurs historiques que pour les réacteurs existants et ceux du futur (EPR2, RNR, SMR). Il détaille les approches spécifiques comme le coût « Champsaur » ou le « coût courant économique » retenu par la Cour des Comptes en France.
Les coûts du combustible nucléaire
Authors: EVANS Cécile , GABRIEL Sophie , POLAK Christian , VALBUENA Philippe
Published: February 2023

Ce chapitre analyse les diverses étapes du cycle du combustible nucléaire : exploration et production d’uranium, technologies de l’enrichissement de l’uranium, techniques de fabrication du combustible, valorisation des matières issues du recyclage. Il précise la notion de ressources et de réserves conventionnelles et non conventionnelles. Il regarde l’évolution de l’offre et de la demande d’uranium à l’échelle mondiale sur longue période et présente les principaux acteurs (pays et compagnies). Il étudie l’évolution du prix de l’uranium et la structure des marchés (contrats de long terme et marché spot).
La gestion des combustibles usés
Authors: CANTARELLA Jacques , EVANS Cécile , KUNSCH Pierre , LÉONARD Didier , MINON Jean-Paul
Published: February 2023

Ce chapitre analyse les caractéristiques des cycles nucléaires ouvert et fermé (recyclage). Il aborde le monorecyclage et le multirecyclage de l’uranium et du plutonium. Il présente les coûts et modes de financement de la gestion des déchets pour l’entreposage de longue durée comme pour le stockage géologique profond (avec présentation de diverses expériences). Il aborde les incertitudes et risques des solutions retenues : fonds dédiés, provisions.
Les enjeux industriels du nucléaire
Authors: URSAT Xavier
Published: February 2023

Ce chapitre analyse les enjeux industriels de la filière nucléaire française et sa restructuration depuis 2015. Il aborde en détail le développement de la filière de 3ème génération (EPR) et les projets de nouveaux réacteurs, y compris les SMR (projet Nuward). Il analyse également le plan Excell mis en place par EDF pour améliorer les compétences de la filière et les enjeux liés à la prolongation de la durée d’exploitation du parc actuel. Une attention particulière est donnée aux conditions et aux coûts de démantèlement des installations nucléaires (principe du pollueur-payeur et principe du préfinancement des opérations via des provisions).
La province métallogénique du craton de Leo-Man en Afrique de l’Ouest
Authors: EGLINGER Aurélien , ANDRÉ-MAYER Anne-Sylvie , THÉBAUD Nicolas , MASUREL Quentin
Published: February 2023

La province métallogénique d’Afrique de l’Ouest contient une large variété de minéralisations. Eglinger et al. soulignent l’importance d’une caractérisation multi-échelle de ces gisements pour en comprendre les modalités de mise en place dans un contexte tectonique précisé au mieux, comme par exemple pour l’or Archéen, signature régionale, ou pour les gisements de type sulfures massifs et porphyres, d’âge paléo-protérozoïque.