bluuebunny/crossref_metadata_2025 huggingface dataset:
Prinsip Kerja Sensor Elektrokimia dalam Penentuan Chemical Oxygen Demand (COD): Review
Authors: Wardani Nur Indah , Purwaningsih Septi , Angeline Annisa Yuliana , Ningrum Sari Sekar , Ardani Muhamad Sofi , Shadiq Zhilal
Published: February 2025

Peningkatan kebutuhan sumber air akibat tingginya populasi masyarakat memerlukan perhatian terhadap uji kualitas air. Chemical Oxygen Demand (COD) adalah indikator jumlah limbah organik di dalam air. Penggunaan sensor elektrokimia dalam pengukuran COD memberikan keuntungan lebih, seperti sensitivitas tinggi dan biaya murah. Pengukuran COD menggunakan sensor elektrokimia didasarkan pada reaksi oksidasi elektrokimia senyawa organik melalui reaksi dengan radikal hidroksil (.OH) pada elektroda kerja (WE). Terdapat 2 prinsip kerja yang digunakan dalam reaksi oksidasi limbah organik, yaitu degradasi fotokatalitik dan oksidasi elektrokatalitik. Melalui degradasi fotokatalitik, limbah organik dioksidasi pada permukaan material fotokatalitik di bawah pencahayaan (light illumination) yang telah menghasilkan radikal hidroksil (.OH). Pada oksidasi elektrokatalitik menggunakan anoda (BDD, PbO2, dan Cu) yang mempunyai kemampuan elektrokatalitik untuk melakukan proses reaksi oksidasi limbah organik.
Studi Etnobotani Herbal Untuk Kesehatan pada Masyarakat Desa Dampit dan Pamotan Kecamatan Dampit Kabupaten Malang
Authors: Hadiarti Salsabila Putri , Hayati Ari , Zayadi Hasan
Published: February 2025

Penggunaan tumbuhan sebagai bahan herbal mengikuti perkembangan kemajuan manusia dan masih berlanjut sampai sekarang. Berbagai teknik telah digunakan dalam penelitian tumbuhan herbal mencakup pendekatan etnobotani. Penelitian ini bertujuan untuk mengetahui jenis tumbuhan yang dimanfaatkan sebagai herbal untuk kesehatan, cara penggunaan, cara mengolah,, dan distribusi jenis tumbuhan di daerah masyarakat Desa Dampit dan Desa Pamotan Kecamatan Dampit. Metode penelitian yang digunakan deskriptif eksploratif dengan pengambilan sampel responden secara purposive sampling sebanyak 10 informan. Data jenis tumbuhan, cara pengolahan dan cara penggunaan serta jumlah jenis tumbuhan dianalisis secara deskriptif. Hasil penelitian menunjukkan spesies tumbuhan yang dimanfaatkan untuk kesehatan adalah 24 spesies tersebar pada 16 familia. Familia tumbuhan dengan jumlah jenis tertinggi adalah Zingiberaceae (9 jenis), Cucurbitaceae (3 jenis), dan 1 jenis pada 14 familia. Bagian tumbuhan yang dimanfaatkan sebagai herbal untuk kesehatan ada 5 yaitu daun, buah, rimpang, umbi, dan kulit buah. Cara penggunaan tumbuhan herbal oleh masyarakat secara rutin (29%) dan tidak rutin (71%). Cara pengolahan ada 4 yaitu, direbus, diseduh, dimakan langsung, dan di blender. Hasil analisis distribusi terdapat 10 jenis tumbuhan yang tersebar di Desa Dampit (54% sebaran individu, 37,5% sebaran jenis) dan Desa Pamotan (45% sebaran individu, 29% sebaran jenis). Nilai distribusi tertinggi (100%) dijumpai pada 6 jenis tumbuhan.
Social Infrastructures for Post-Growth Value Generation: School-Based Initiatives in London
Authors: Natarajan Lucy
Published: February 2025

This paper investigates the stimulation of value through social infrastructures; it explores the potential of public educational facilities focusing on an initiative in London known as ‘School Superzones’. There is growing attention on how the social underpinnings of places
might generate alternative forms of economic value. Given that top-down and growth focused types of interventions fail to deliver on maintaining long-term community wellbeing, social infrastructures might off er a route to non-growth dependent alternatives. As shown in this paper, the telos
of School Superzones is the generation of local social value and place-based liveability, and that they open up partnership routes to rework expectations of returns from monetary investments. While they face challenges inherent in existing dependencies and relationships in London, and their
wellbeing impacts will take time to evidence, they demonstrate post-growth directions through school partnerships and the importance of nurturing in-kind volunteered eff orts and growing social capital.
Learning from an Ordinary Suburban Post-Growth Struggle: Not by Design, Nor by Disaster
Authors: Cerrada Morato Lucia
Published: February 2025

Suburbs worldwide are described as unsustainable given the high levels of resource consumption, waste disposal, and their vulnerability to climate change. While mainstream academic and policy discourses have long focused on densification ‐ hence growth ‐ as a solution
to address the suburban sustainability crisis, an emerging body of scholarship suggests that the spatial and socio-technical structure of suburbs may off er opportunities for a postgrowth scenario. However, much of this literature remains either theoretical or rooted in narrow, anecdotal examples
of single policy interventions, which replicate some of the shortcomings seen in broader postgrowth and degrowth studies. By exploring an ‘ordinary’ postgrowth transition in a medium-sized city in Southern Europe, I argue that such a shift will not unfold as suggested by existing
literature: neither as a purely top-down or bott om-up process, nor as a totalizing victory or defeat, or a binary outcome of ‘by Design or Disaster’. Instead, a suburban postgrowth transition emerges as a multi-actor, multi-scalar, and multi-dimensional process of multiple niches,
where although there is a broad consensus on the need to transition away from a growth-dependant water and sanitation system, a struggle for a more radical postgrowth future is taking place.
Sensitivity of flood-prone areas to extreme rainfall using AHP and fuzzy AHP: a case study of Boussellam and K'sob watersheds, Algeria
Authors: Benaiche Morad , Mokhtari Elhadj , Berghout Ali , Abdelkebir Brahim , Engel Bernard
Published: February 2025

Mapping flood-prone areas’ sensitivity to extreme rainfall is crucial for disaster risk reduction. Using the analytical hierarchy process (AHP) and fuzzy AHP methods with Geographic Information Systems (GIS) data, including factors like slope, elevation, precipitation, land use, and vegetation indices, enhances disaster preparedness. This approach enables creating maps that support informed decision-making for community resilience. In this study, AHP and fuzzy AHP models were applied across different return periods (2, 5, 10, 100, and 1,000 years) and average annual rainfall, revealing that high-risk areas vary by model: the AHP model showed high susceptibility in 2.19–25.55% of the area, while the fuzzy AHP model identified 1.53–24.51% as very sensitive. These risks are concentrated in the low-slope zones of the Boussellam and K'sob watersheds, posing a threat to three out of four nearby cities for 100-year or longer events.
Entre as tecnologias de poder disciplinar e de controle: um estudo de caso sobre o Centro de Atenção Psicossocial Álcool e Drogas (CAPS AD)
Authors: Corbanezi Elton Rogerio , De Amorim Barros Alexandre Cesar
Published: February 2025

Presencia-se atualmente transformações nas estratégias contemporâneas de poder: as emergentes técnicas de controle ao “ar livre”, associadas à governamentalidade neoliberal, coexistem com técnicas coercitivas das sociedades disciplinares. Os imperativos da competição, do desempenho, da autonomia e da liberdade, próprios da subjetivação contemporânea, se articulam com as tecnologias de vigilância e punição nas diferentes esferas sociais, implicando tanto a normalização individual quanto a produção da saúde mental. A partir dessa discussão, este artigo interpreta os discursos e as práticas terapêuticas de um Centro de Atenção Psicossocial Álcool e Drogas (CAPS AD) no estado de Mato Grosso. Para o estudo de caso, utilizamos os seguintes procedimentos de pesquisa: revisão bibliográfica, análise documental, produção de dados empíricos por meio de entrevistas com os profissionais da instituição, observação da estrutura e rotina da instituição e o acesso a fontes documentais sobre a demanda de atendimento e o tratamento da clientela. Após análise dos dados, sustentamos que as tecnologias modernas e contemporâneas de poder se justapõem e se entrelaçam no tratamento ofertado pelo CAPS AD, de modo que tanto o paradigma contemporâneo baseado na redução de danos quanto o da lógica manicomial moderna se articulam na instituição mediante discursos e práticas. Evidenciamos, assim, a manifestação de uma tecnologia de poder híbrida de normalização e de gestão da saúde mental.
Opioid Use Disorders: Prevention, Diagnosis, and Treatment Strategies to Mitigate Addiction Risks
Authors: Agarwal Uma , Singhal Khushboo , Tonk Rajiv Kumar
Published: February 2025

Opioid Use Disorder (OUD) is defined by the persistent use of opioids despite adverse
consequences. It is associated with increased mortality and a variety of mental and general
medical comorbidities. Risk factors include younger age, male sex, lower educational attainment,
lower income, and psychiatric disorders, such as other substance use disorders and mood
disorders. Genetics also play a role in susceptibility to opioid use disorders. Long-term selfefficacy
in opioid use for non-medical purposes suggests irreversible opioid use disorders.
To evaluate the current understanding of opioid use disorders, the limitations in existing treatment
approaches were examined, and strategies to improve outcomes through expanded treatment
access and personalized care interventions were identified.
An analysis was carried out regarding the role of existing pharmacological treatments, barriers
within the care cascade, and potential advancements in healthcare delivery and innovation was
carried out to address opioid use disorders. A comprehensive review of the literature was conducted
by searching electronic databases (e.g., PubMed, Scopus) for articles published over the
past 20-25 years. Relevant studies were selected based on predefined inclusion criteria, focusing
on OUD risk factors, pharmacological treatments, barriers in the care cascade, and strategies for
improving care. The selection process prioritized systematic reviews, clinical trials, and key
guidelines.
Although medications for opioid use disorders are effective, their impact is hindered by systemic
issues at multiple levels of care. Addressing these challenges requires comprehensive efforts, including
professional training, innovative treatments, and healthcare reforms to expand access
and personalize care.
Atractylenolide I Inhibits the Growth of Esophageal Cancer Cells by Inhibiting the Wnt/Β-Catenin Pathway
Authors: Lian Maowei , Zhang Yunxiang , Li Xu , Niu Na , Tang Dong , Cao Lihua , Li Yong , Xiang Xiaocong , Yu Chunlei
Published: February 2025

Background:

Esophageal cancer is a highly lethal cancer with a rapidly increasing incidence and a
poor prognosis. Atractylenolide I is a natural sesquiterpene lactone extracted from the rhizome of the Asteraceae
plant, which has a variety of pharmacological effects, such as anti-inflammatory and immunomodulatory. Still, its
impact on esophageal cancer has not been reported. Therefore, this study investigated the in vitro and in vivo
effects of Atractylenolide I on the growth and proliferation of esophageal cancer and explored its possible mechanisms.

Methods:

To evaluate the effect of atractylenolide I on esophageal cancer cells, apoptosis assay and cell cycle
assay tests were performed. Atractylenolide I was used to treat esophageal cancer cells for 48 hours, and flow
cytometry detects apoptosis and cell cycle. The Wnt/β-catenin-related pathway proteins were then detected by
Western blotting. For in vivo studies, an esophageal cancer graft tumor model was established subcutaneously in
BALB/c nude mice, which were given Atractylenolide I treatment for 2 weeks.

Result:

The result shows that Atractylenolide I inhibited the proliferation and induced apoptosis of esophageal
squamous carcinoma and adenocarcinoma cells. Further research shows that Atractylenolide I inhibited the
Wnt/β-catenin signaling pathway, decreased the expression of CCND1, MYC, and FN1 genes, and thus increased
the apoptosis of esophageal cancer cells and blocked the cell cycle in G0/G1 phase, hence exerting the role of
inhibiting esophageal cancer cells in vivo and in vitro.

Conclusion:

This study indicates that Atractylenolide I is an efficient lead compound for the treatment of esophageal
cancer, providing a theoretical basis for further clinical development and application of Atractylenolide I.
Clinical and In vitro Data Shed New Light on the Therapeutic Advantages of Black Seeds (Nigella sativa) for the Treatment of Hepatitis C and Hepatitis B Viral Infections
Authors: Maideen Naina Mohamed Pakkir , balasubramanian Rajkapoor , Balasubramanian Kumar , Hussain Mohamed Harsath Jahir , Shahul Hameed Mohamed Fahath , Senthil Rethesh
Published: February 2025

Background:

Hepatitis C Virus (HCV) and Hepatitis B Virus (HBV) can cause acute and chronic viral infections. Due to their higher costs, potential side effects and drug interactions, and associated risks, some patients with HCV and HBV infections may not be able to afford conventional antiviral medications.

Objective:

The goal of this review paper is to highlight the advantages of Nigella sativa, or black seeds, in the treatment of patients with HCV and HBV infections.

Methods:

Medline/Pubmed/PMC, Scopus, Web of Science, Google Scholar, Science Di-rect, Ebsco, Embase, and reference lists were searched to locate the research studies that assessed the effects of different black seed (N. sativa) preparations on the telltale signs and symptoms of HCV and HBV infections.

Results:

Numerous preclinical and clinical investigations have suggested that black seeds (N. sativa) may be effective against HCV and HBV infections. Furthermore, N. sativa, or black seeds, have demonstrated a range of pleiotropic effects, such as antiviral activity against multiple other viruses and anti-inflammatory, antioxidant, and immunomodulatory properties that can lessen the symptoms and indicators of HCV and HBV infections.

Conclusion:

Patients with HCV and HBV infections may benefit from using black seeds (N. sativa) as an adjuvant therapy in addition to conventional therapy. Additional random-ized controlled clinical trials would confirm the safety and effectiveness of Nigella sativa (black seeds) in treating HCV and HBV infections.
Comorbidity of ADHD, but not Tics, has Detrimental Impact in Adults with OCD
Authors: Tan Oguz
Published: February 2025

Background:

Obsessive-compulsive disorder (OCD) frequently cooccurs
with tic disorders (TD) and attention deficit and hyperactivity disorder
(ADHD). Data on adults are limited because most studies focus on children.

Objective:

We aimed to investigate the clinical and sociodemographic impact on
adults of the comorbidity of OCD with ADHD or TD.

Method:

We screened 356 adults seeking treatment for OCD in a cross-sectional
observational study for past or present ADHD and TD. We used the Yale-
Brown Obsessive-Compulsive Scale (Y-BOCS), Hamilton Depression Rating
Scale-17 Item (HDRS-17) and Beck Anxiety Inventory (BAI). We also questioned
parameters mainly involving adult life, such as marital status, unemployment
rate, educational attainment, suicide attempts (SA), hospitalization, alcohol
use disorder (AUD), substance use disorder (SUD) and smoking.

Results:

Of 356 adults, 71.07% had OCD only, 15.45% OCD+ADHD, 8.15%
OCD+TD and 5.34% OCD+ADHD+TD. Y-BOCS scores did not differ among
these categories. The comorbidity of ADHD was generally characterized by
higher HDRS-17 and BAI scores, higher prevalence of AUD/SUD, fewer years
of education and a higher percentage of non-married, divorced, and unemployed
individuals. SA and rates of hospitalization were similar across the four categories.
TD had no relationship with any of these characteristics.

Conclusion:

In adults with OCD, past or present ADHD has deleterious effects
on anxiety, depressive symptoms, educational attainment, employment and marital
status, whereas TD is not associated with any worsening of clinical or sociodemographic
characteristics.

conclusion:

In adults with OCD, past or present ADHD has deleterious effects on anxiety, depressive symptoms, educational attainment, employment and marital status whereas TD is not associated with any worsening of clinical or sociodemographic characteristics.
Evaluation of Vaccination Hesitancy in Medical Faculty Students
Authors: Çakır Mustafa , Elbay Durmaz Deniz , Malakcıoğlu Cem , Kırlangıç Merve , İkiışık Hatice , Mutlu Hasan Hüseyin , Maral Işıl
Published: February 2025

Aim: This research aims to assess vaccine hesitancy among medical students.
Method: This descriptive study was conducted with 615 students in years 1, 2, 3, 4, 5, and 6 at a medical faculty in Istanbul. The first nine questions of the online survey developed by the researchers focused on socio-demographic characteristics, while the next 14 questions were prepared to address vaccine hesitancy. A significance level of p < 0.05 was considered in all analyses.
Results: The participants in the study were between the ages of 17 and 29; 58% were female. General vaccine hesitancy was observed in 7.6% of the students. The frequency of hesitancy regarding the COVID-19 (Coronavirus disease 2019) vaccine among the participants was 17.4%, and a higher rate of indecision regarding the COVID-19 vaccine was found (18.9%). The frequency of general vaccine hesitancy in preclinical students was higher than in clinical students (p < 0.05).
Conclusions: In this study, COVID-19 vaccine acceptance rates were higher compared to the general population, and general vaccine hesitancy was significantly lower in clinical term students compared to preclinical students. Vaccine information and advocacy training starting from the first year of medical education could help future physicians guide society.
Fiziksel Tıp ve Rehabilitasyon Uzmanlarının Multidisipliner Sağlık Hizmetlerindeki Kritik Rolü
Authors: Özbek İlhan Celil
Published: February 2025

Derginizin 18. Cilt 4. sayısında, Sayın İnan ve ark. tarafından kaleme alınan "Sağlık Hizmetlerinde Çok Disiplinli Yaklaşım Uygulamaları: Aile Hekimliği ve Ergoterapi" başlıklı derleme, sağlık hizmetlerinde disiplinler arası işbirliğinin önemini vurgulayan değerli bir çalışma olmuştur. Bu kapsamlı bakış açısını memnuniyetle karşılarken, fiziksel tıp ve rehabilitasyon uzmanlarının bu süreçteki kritik rolünün daha fazla vurgulanmasının multidisipliner yaklaşımı güçlendireceğine inanıyorum.
Pengaruh Leverage, Board of Directors, Dan Operating Capacity Terhadap Financial Distress Di Masa Pandemi Covid-19
Authors: Bani Amira Yusyah , Hariadi Bambang
Published: February 2025

The pandemic has changed the world, including Indonesia that suffers from economic contraction through the government new policies in coping to reduce the pandemic outbreak. As such, this study aims to determine the effect of leverage, board of directors and operating capacity on financial distress during the covid-19 pandemic. The samples include 30 transportation and logistics companies listed on the Indonesia Stock Exchange for the period of 2020-2022, and the data are analyzed by structural equation modeling (SEM) utilizing the partial least square (PLS). This study finds that leverage and board of directors are able to affect the potential for financial distress in a company. However, operating capacity in this study has no effect on the potential for financial distress in a company. This study supports agency theory, and applies earnings per share in measuring financial distress proxies.
 
Abstrak
Pandemi mampu mengubah dunia. Dengan adanya pandemi, pemerintah telah mengeluarkan berbagai kebijakan baru sebagai upaya dalam menaggulangi dan mengurangi wabah pandemi. Imbas dari kebijakan tersebut hal ini memberikan kontraksi pertumbuhan terhadap ekonomi Indonesia.  Penelitian ini bertujuan untuk mengetahu pengaruh leverage, board of directors dan operating capacity terhadap financial distress di masa pandemi covid-19. Penelitian ini menggunakan structural equation modelling (SEM) dengan mengunakan jenis partial least square (PLS). Adapun sampel penelitian adalah 30 perusahaan sektor transportasi dan logistik di Bursa Efek Indonesia periode 2020-2022. Penelitian ini menemukan bahwa leverage dan board of directors mampu mempengaruhi potensi terjadinya financial distress pada suatu perusahaan. Namun, operating capacity dalam penelitian ini tidak berdampak atau tidak berpengaruh pada potensi munculnya financial distress pada suatu perusahaan. Penelitian ini mendukung teori keagenan. Penelitian ini menggunakan earning per share pada pengukuran proksi financial distress.
Reaksi Pasar Modal Indonesia Terhadap Perdagangan Perdana Bursa Karbon Indonesia
Authors: Najubah Zian , Djazuli Atim
Published: February 2025

The objective of this research is to assess and analyze the reaction of the capital market to the initial trading of carbon exchange, which is measured using abnormal return, cumulative abnormal return, dan trading volume activity, before and after the event. This event study assesses the impact of an event on stock prices. The research period is fifteen working days, i.e. seven days before, one day during, and seven days after the initial carbon trading. Using purposive sampling, six companies consisting of forestry industry, paper, and renewable energy firms listed on the Indonesia Stock Exchange were selected as the sample. The incorporated methods are Wilcoxon signed-rank test and paired sample t-test before and after the event. This study finds that the average abnormal returns before and after the initial carbon trading are not different, that the cumulative average abnormal returns before and after the event are different, and that the average trading volumes before and after the carbon trading are not different.
 
Abstrak
Penelitian ini memiliki tujuan untuk menguji dan menganalisis reaksi pasar modal terhadap perdagangan perdana bursa karbon yang diukur melalui variabel indikator abnormal return, cumulative abnormal return, dan trading volume activity pada sebelum dan sesudah peristiwa. Jenis penelitian yang digunakan adalah studi peristiwa untuk menilai dampak dari suatu peristiwa terhadap harga saham. Periode penelitian yang digunakan adalah 15 hari kerja Bursa Efek Indonesia yang terdiri dari 7 hari sebelum, 1 hari event date, dan 7 hari sesudah perdagangan perdana bursa karbon. Penelitian ini menggunakan teknik purposive sampling sehingga didapatkan 6 sampel perusahaan industri perhutanan, kertas, dan energi terbarukan yang terdaftar di Bursa Efek Indonesia. Metode penelitian yang digunakan adalah uji beda wilcoxon signed rank test dan paired sample t-test pada sebelum dan sesudah peristiwa. Hasil dari penelitian ini adalah variabel average abnormal return pada sebelum dan sesudah perdagangan perdana bursa karbon tidak memiliki perbedaan. Sedangkan, variabel cumulative average abnormal return pada sebelum dan sesudah perdagangan perdana bursa karbon memiliki perbedaan. Kemudian, variabel average trading volume activity tidak memiliki perbedaan pada sebelum dan sesudah perdagangan perdana bursa karbon.
Perilaku Herding Pada Harga Saham Sektor Energi
Authors: Rasiv Achmad Wildan , Juwita Himmiyatul Amanah Jiwa
Published: February 2025

The need of human to make investments has encouraged them to invest in capital markets through, one of which, stocks. One of the stock sectors in the Indonesia Stock Exchange that has a good performance is energy. The classical financial theory assumes that investors should behave rationally in making decisions. However, this does not necessarily the case since there are chances for the occurrence of market anomaly due to herding behavior, which explains the inefficiency of markets. The objective of this research is to detect herding behavior in the prices of stocks in energy sector during the 2019-2022 period in all market conditions, in favorable market condition, and in unfavorable market condition. The herding behavior in this quantitative study was detected using the Cross-Sectional Absolute Deviation (CSAD) method, in which the non-linear relationship between return and CSAD was observed. The samples are 34 energy sector companies, selected via purposive sampling. The study incorporates secondary data of monthly closing prices of both the stocks and the Indonesia’s Composite Index. The results of the data analysis and hypothesis testing in EViews 12 indicate that herding behaviors were detected in the prices of stocks in the energy sector in the Indonesia Stock Exchange during the 2019-2022 period in all market conditions and in unfavorable market condition. This study also finds that there is no herding behavior in the unfavorable market condition during the 2019-2022 period.
 
Abstrak
Kebutuhan manusia untuk berinvestasi mendorong adanya investasi pada pasar modal, salah satunya adalah saham. Di Bursa Efek Indonesia, salah satu sektor saham yang memiliki performa baik adalah sektor energi. Teori keuangan klasik menyatakan bahwa investor seharusnya bertindak rasional dalam melakukan pengambilan keputusan investasi. Namun, hal ini tidak selalu terjadi dan terdapat peluang adanya anomali pasar yang disebabkan oleh perilaku herding yang menjelaskan bahwa pasar tidak senantiasa efisien. Penelitian ini bertujuan untuk mendeteksi perilaku herding pada harga saham sektor industri selama periode 2019-2022 pada keseluruhan kondisi pasar, kondisi pasar naik, dan kondisi pasar turun. Penelitian ini menggunakan pendekatan kuantitatif. Metode yang digunakan dalam mendeteksi herding adalah Cross Sectional Absolute Deviation (CSAD) dengan melihat hubungan non-linear return pasar dan CSAD. Sampel yang digunakan adalah 34 perusahaan sektor energi dengan teknik purposive sampling. Data yang digunakan adalah data sekunder harga penutupan bulanan saham tersebut dan IHSG pada periode 2019-2022. Analisis data dilakukan dengan pengujian hipotesis dengan perangkat lunak Eviews 12. Hasil penelitian ini menunjukkan bahwa terdapat perilaku herding pada harga saham sektor energi di Bursa Efek Indonesia periode 2019-2022 pada keseluruhan kondisi pasar dan kondisi pasar turun. Namun, tidak ditemukan perilaku herding pada kondisi pasar naik selama periode 2019-2022.
Standardization Aspects of Concrete 3D Printing
Authors: Vasilic Ksenija
Published: February 2025

Digital fabrication with concrete has the potential to contribute to sustainability as a resource-efficient construction method. However, the absence of standardized testing, processing and approval procedures hinders the widespread adoption of 3D printing in concrete construction. The need for uniform testing procedures and processing requirements is crucial to overcome the complexities, lengthiness, and costliness of current construction processes, ultimately promoting the quality and reliability of 3D printed structures. This paper examines the current state of development, identifies gaps in existing standards, and proposes initial steps towards European-level standardization.
Enhancing Text Message Support With Media Literacy and Financial Incentives for Vaping Cessation in Young Adults: Protocol for a Pilot Randomized Controlled Trial
Authors: Michaud Tzeyu , Puga Troy , Archer Rex , Theye Elijah , Zagurski Cleo , Estabrooks Paul , Dai Hongying Daisy
Published: February 2025

Background

The persistent high prevalence of e-cigarette use among young adults remains a significant public health concern, with limited evidence and guidance on effective vaping cessation programs targeting this population.

Objective

This study aims to outline the study design and protocol of a pilot randomized controlled trial aimed at investigating feasibility and assessing whether media literacy education or financial incentives enhance the effectiveness of evidence-based text message support in promoting vaping abstinence among young adult e-cigarette users.

Methods

The pilot study uses a 4-arm (1:1:1:1) randomized controlled trial design to assess the potential impact of different combinations of media literacy education, financial incentives, and text message support on vaping abstinence over a 3-month period. The first month serves as a preparatory phase for quitting, followed by 2 months focused on abstinence. A total of 80 individuals, aged 19-29 years, who have used e-cigarettes within the past 30 days, have internet access, and express interest in quitting vaping within the next 30 days, will be enrolled. Eligible individuals will be randomized into one of the four study groups: (1) Text Message, (2) Media Literacy, (3) Financial Incentive, and (4) Combined. All participants, regardless of group assignment, will receive text message support. Participants will be followed for 12 weeks, with abstinence status assessed at week 12, as well as during remote check-ins at weeks 6, 8, and 10. Feasibility measures include recruitment rate, reach, engagement, and retention. Other outcomes of interest include self-reported 7-day abstinence and changes in nicotine dependence and media literacy scores. Exit interviews will be conducted with those who complete the study to explore facilitators of and barriers to participation and engagement in vaping cessation, which will inform future program refinement and uptake.

Results

Recruitment for the study commenced in December 2023 and concluded in August 2024. A total of 40 participants were randomized into these groups: 9 for Text Message, 11 for Media Literacy, 10 for Financial Incentive, and 10 for the Combined group. The final assessment was completed in November 2024, and analyses are currently ongoing.

Conclusions

The findings from this trial could provide valuable insights into the design and uptake of vaping cessation strategies among the young adult population.

Trial Registration

ClinicalTrials.gov NCT05586308; https://clinicaltrials.gov/study/NCT05586308

International Registered Report Identifier (IRRID)

DERR1-10.2196/60527
Enhancing Text Message Support With Media Literacy and Financial Incentives for Vaping Cessation in Young Adults: Protocol for a Pilot Randomized Controlled Trial (Preprint)
Authors: Michaud Tzeyu , Puga Troy , Archer Rex , Theye Elijah , Zagurski Cleo , Estabrooks Paul , Dai Hongying Daisy
Published: February 2025

BACKGROUND

The persistent high prevalence of e-cigarette use among young adults remains a significant public health concern, with limited evidence and guidance on effective vaping cessation programs targeting this population.

OBJECTIVE

This study aims to outline the study design and protocol of a pilot randomized controlled trial aimed at investigating feasibility and assessing whether media literacy education or financial incentives enhance the effectiveness of evidence-based text message support in promoting vaping abstinence among young adult e-cigarette users.

METHODS

The pilot study uses a 4-arm (1:1:1:1) randomized controlled trial design to assess the potential impact of different combinations of media literacy education, financial incentives, and text message support on vaping abstinence over a 3-month period. The first month serves as a preparatory phase for quitting, followed by 2 months focused on abstinence. A total of 80 individuals, aged 19-29 years, who have used e-cigarettes within the past 30 days, have internet access, and express interest in quitting vaping within the next 30 days, will be enrolled. Eligible individuals will be randomized into one of the four study groups: (1) Text Message, (2) Media Literacy, (3) Financial Incentive, and (4) Combined. All participants, regardless of group assignment, will receive text message support. Participants will be followed for 12 weeks, with abstinence status assessed at week 12, as well as during remote check-ins at weeks 6, 8, and 10. Feasibility measures include recruitment rate, reach, engagement, and retention. Other outcomes of interest include self-reported 7-day abstinence and changes in nicotine dependence and media literacy scores. Exit interviews will be conducted with those who complete the study to explore facilitators of and barriers to participation and engagement in vaping cessation, which will inform future program refinement and uptake.

RESULTS

Recruitment for the study commenced in December 2023 and concluded in August 2024. A total of 40 participants were randomized into these groups: 9 for Text Message, 11 for Media Literacy, 10 for Financial Incentive, and 10 for the Combined group. The final assessment was completed in November 2024, and analyses are currently ongoing.

CONCLUSIONS

The findings from this trial could provide valuable insights into the design and uptake of vaping cessation strategies among the young adult population.

CLINICALTRIAL

ClinicalTrials.gov NCT05586308; https://clinicaltrials.gov/study/NCT05586308

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/60527
The use of natural language processing to interpret unstructured patient feedback on health services: A scoping review (Preprint)
Authors: Feizollah Ali , Lin Chiu-Yi , O'malley Lucy , Thompson Wendy , Listl Stefan , Byrne Matthew
Published: February 2025

BACKGROUND

Unstructured patient feedback (UPF) allows patients to freely express their experiences without the constraints of predefined questions. The proliferation of online healthcare rating websites has created a vast source of UPF. Natural language processing (NLP) techniques, particularly sentiment analysis and topic modelling, are increasingly being used to analyse UPF in healthcare settings, however the scope and clinical relevance of these technologies is unclear.

OBJECTIVE

This scoping review investigates how NLP techniques are being used to interpret UPF, with focus on the healthcare settings in which this is used, the purposes for using these technologies, and any impacts reported on clinical practice.

METHODS

Searches of the MEDLINE, EMBASE, CINAHL, Cochrane Database of Reviews, and Google Scholar were conducted in February 2024. No date limits were applied. English language studies that used NLP techniques on UPF that pertained to an identifiable health care setting or provider were included. Data extraction focused on the healthcare setting, NLP methods used, and applications of these techniques.

RESULTS

52 studies were included. NLP was most commonly applied to UPF from secondary care settings (n=33) with fewer in primary (n=10) or community (n=5) care. Three NLP techniques were identified in the included studies: sentiment analysis (n=32), topic modelling (n=15) and text classification (n=7). Sentiment analysis was applied to explore associations between patient sentiment and healthcare provider characteristics, track emotional responses over time, and identify areas for improvement in healthcare delivery. Topic modelling, primarily using Latent Dirichlet Allocation (LDA) algorithm, was employed to uncover latent themes in patient feedback, compare patient experiences across different healthcare settings, and track changes in patient concerns over time. Text classification was used to categorize patient feedback into predefined topics. The association between NLP-derived insights and traditional healthcare quality metrics was limited, with few studies describing concrete clinical impacts resulting from their analyses.

CONCLUSIONS

NLP has been applied to UPF across a number of contexts, primarily to identify features of health services or professionals that support good patient experience. The growth of research publications demonstrates an academic interest in these technologies, but there is little evidence these approaches are being employed in clinical settings. Future research is required to assess how NLP may capture the nuance of healthcare interactions, align with existing quality metrics and how it may be used to influence clinician behaviour
Evaluating the Impact of eHealth Tools as Add-ons to Face-to-Face Treatment for Adults with Alcohol and Substance Use Disorders: An overview. (Preprint)
Authors: Bachmann Silke , Penzenstadler Louise E.
Published: February 2025

BACKGROUND

A large number of applications (apps) is available for individuals with addiction problems, the majority of which is available freely and not subject to research.

OBJECTIVE

This paper studies the additional benefit and outcome in alcohol and substance use disorder (AUD, SUD), when professional managed apps are added to face-to-face treatment.

METHODS

A literature search on randomized controlled trials (RCT) was carried out, where treatment as usual (TAU) was compared to TAU supplemented by an app. TAU was defined as the type of regular treatment at the respective treatment site. Between 2014 and 2023 sixteen RCTs added an app to at least one randomized group in adults suffering AUD and SUD.

RESULTS

There was a broad variation with respect to the range of disease severity and the presence of co-morbidities. Active app elements were presentation of information, monitoring, motivational tools, psychotherapeutic tools, crisis intervention and communication with professionals. Interventions lasted from 1 to 12 months, follow-ups were executed in 9 studies. Results speak in favor of reduction of substance use in terms of days of use and / or days of heavy use by introduction of an app. A time-related pattern arose with early improvement in most studies, levelling off of the effects after several months, but with good results for individuals who stayed in treatment for about one year.

CONCLUSIONS

Overall, hybrid approaches in addiction treatment may cost-efficiently enhance effectiveness of treatment and reach individuals in remote areas. They should be integrated into professional care, but not replace it.

CLINICALTRIAL

n/a
Sistematización de la Colección Paleontológica del Museo Regional de Antropología e Historia de Baja California Sur
Authors: Morales Ortega Priscila , Hernández Cisneros Atzcalli Ehécatl
Published: February 2025

El estado de Baja California Sur se caracteriza por su riqueza paleontológica, la cual ha sido de gran interés científico, económico y social. Sin embargo, varios factores limitan la investigación paleontológica en la región, uno de ellos es el exiguo desarrollo de las colecciones de carácter científico con registro fósil, a pesar de que existe gran interés en la comunidad científica nacional y extranjera. En el presente trabajo se realizó una sistematización de la creciente colección paleontológica del Museo Regional de Antropología e Historia de Baja California Sur. Se documentaron y catalogaron un total de 371 ejemplares fósiles, y se clasificaron 41 taxones a nivel género. El 68.4% del catálogo se constituyó por invertebrados, el 26.2% por vertebrados, el 4.1% por maderas fósiles, y el 1.4% por icnofósiles y réplicas. Finalmente, el ordenamiento de esta colección permitió reconocer parte de las condiciones y estado actual en las que se encuentran las colecciones fósiles del estado. La presente colección constituye el primer registro fósil documentado y catalogado en el estado. Además, cabe resaltar que visibilizar las colecciones no solo implica la perspectiva científica, sino también realzar una relevante entidad social, la cual trae beneficios de desarrollo en términos económicos, conocimiento, salud, identidad, conservación y protección del patrimonio biocultural estatal y del país.
Steganographic Cryptosystem Based on the Use of Chaos Theory and Cellular Automata
Authors: Arias-Cárdenas Marlon , Alvarado-Nieto Deicy , Amaya-Barrera Isabel
Published: February 2025

The exchange of large amounts of information through public channels has become an everyday occurrence, a situation that generates great risks in the case of possible cyber-attacks and motivates the academic and scientific community to develop new robust security schemes. The objective of the research was to use mathematical and artificial intelligence tools to propose new security schemes. The design and implementation of a crypto-steganographic algorithm for text is described below. The methodology employed consisted of using cellular automata to detect the edges of a carrier image, leveraging the color contrast diversity, and the Tinkerbell chaotic attractor to generate two pseudo-random sequences: one for the encryption scheme and the other to select the edge pixels of the carrier image where cryptogram bits are hidden. Additionally, a verification phase was included in which the receiver provides a code to confirm that the stegoimage was not altered. The system key is shared between the sender and the receiver using the Diffie-Hellman algorithm. The proposed algorithm was subjected to a series of steganographic and cryptographic performance tests, including entropy analysis, mean square error (MSE), correlation coefficients, key sensitivity, peak signal-to-noise ratio (PSNR), normalized root mean square error (NRMSE), and the structural similarity index (SSI). The results of PSNR, MSE and SSI test were compared with scientific benchmarks, revealing indicators that align with the standards of information security. Finally, a crypto-steganographic algorithm was consolidated as a result of an academic exercise whose indicators make it potentially applicable in real-world contexts.
Evaluación de pavimentos permeables como técnica para mitigar picos de escorrentía superficial
Authors: Pantoja Cárdenas Jhoan Sebastián , Zambrano Nájera Jeannette
Published: February 2025

Las inundaciones pluviales causan emergencias y desastres en las ciudades a nivel mundial. Dichas inundaciones se producen principalmente por la impermeabilización de las cuencas. El problema se agrava en ciudades como Manizales, con altas y medias pendientes, ya que se presentan altas velocidades de flujo y por tanto incrementos de los volúmenes de escorrentía, lo que a su vez está asociado con altos caudales punta. Para mitigar dichos efectos negativos han surgido los pavimentos permeables (PP) como infraestructura alternativa. Teniendo en cuenta lo anterior, el objetivo de esta investigación fue evaluar la capacidad de los PP para mitigar las intensidades de escorrentía superficial en cuencas con medias y altas pendientes. La metodología empleada consistió en realizar una modelación hidrodinámica con SWMM en la cuenca experimental Palogrande San Luis, cuenca que presenta las características mencionadas y está ubicada en la ciudad de Manizales, Colombia. Se utilizaron PP para vías vehiculares de tráfico liviano en asfalto permeable, parqueaderos en concreto permeable y áreas comunes en adoquines de concreto permeable. Los PP propuestos para parqueaderos y áreas comunes presentaron reducciones de escorrentía solo entre el 0 % y el 20 %. Se concluye que los PP propuestos en vías vehiculares reducen más la escorrentía superficial que aquellos propuestos en áreas comunes y en parqueaderos debido al área impermeable aportante que le corresponde a cada uno.
Adenocarcinoma comedo-cribiforme de colon, una causa poco frecuente de abdomen agudo: Reporte de un caso
Authors: Sarmiento Bobadilla Jorge Alberto , Correa Bravo Roberto Manuel , Lucas Mera Eli Francisco , Cárdenas Garófalo Lizbeth Leonor
Published: February 2025

El término abdomen agudo engloba un conjunto de enfermedades que tiene como síntoma común el dolor abdominal. Aproximadamente el 20% de las causas de abdomen agudo obstructivo corresponden a neoplasias del tubo digestivo, con más del 90% de los casos de cáncer de colon correspondiendo a adenocarcinomas. Pese a esto, el subtipo comedo-cribiforme es poco frecuente, presentándose en menos del 7% de los adenocarcinomas. Presentamos el caso de un hombre de 72 años con cuadro de dolor abdominal de 4 días de evolución, acompañado de constipación y signos de irritación peritoneal. Se le diagnostica una neoplasia en rectosigma que estaba ocasionando un cuadro de obstrucción intestinal, por lo cual se realiza procedimiento de Hartmann. Luego de la extirpación del tumor, el estudio histopatológico reportó un adenocarcinoma comedo-cribiforme. Este subtipo histológico posee como principal característica la presencia de glándulas con un patrón cribiforme, además de un área de necrosis central similar a la observada en los carcinomas intraductales de mama. Subsecuentemente recibió radioterapia en zona rectal y ciclos de quimioterapia con capecitabina y oxaliplatino. Previo a realizarse restitución de tránsito intestinal paciente fallece por neumonía SARS-CoV-2. Es de recalcar que, ante un paciente con sospecha de abdomen agudo, la historia clínica y los exámenes complementarios son claves para establecer la causa del proceso agudo. En caso que la causa sea de resolución quirúrgica esta debe realizarse a la mayor brevedad posible.
Xantoma estriado palmar
Authors: Maldonado Carrasco Claudia Lucia , Garcés Juan Carlos , Silva María Luisa , Loayza Enrique
Published: February 2025

Los xantomas se caracterizan por ser infiltraciones de células histiocitarias espumosas que contienen lípidos, clínicamente se pueden observar cómo máculas, pápulas, o placas de color amarillo-anaranjado; pueden ser circunscritas o difusas, con localización variable.  Dentro de la variedad de xantomas planos, esta el xantoma estriado palmar, el cuales un signo infrecuente pero patognomónico de hiperlipoproteinemia tipo III.  Se presenta el caso de una paciente femenina de 43 años, que presenta pápulas y placas de color amarillento, hiperqueratósicas localizadas en palmas, principalmente sobre pliegues y surcos palmares. En sus exámenes de laboratorio, pruebas de función hepática alterada y dislipidemia. Se realiza un estudio minucioso de este caso y junto con los hallazgos histopatológicos se confirma un xantoma estriado palmar junto con su hipercolesterolemia marca las directrices para realizar un abordaje multidisciplinario.
Delirio de parasitosis
Authors: Peláez Vélez Luzmila Carolina , Loayza Enrique
Published: February 2025

El delirio de parasitosis es un trastorno psicótico en el que el paciente tiene la creencia falsa de estar infestado. Presentamos en caso una paciente adulta, con un episodio depresivo de base, que acude con lesiones cutáneas autoinfligidas ante la creencia de tener organismos que le caminan y le salen por la piel.
Diabetes Mellitus tipo 2 y riesgo de cáncer de ovario en Loja 2000-2017: un estudio de casos y controles
Authors: Ludeña González Lucía del Carmen
Published: February 2025

Introducción: el cáncer de ovario es una de las principales neoplasias malignas mortales que aquejan a las mujeres. Factores como diabetes mellitus tipo 2 (DM2) u obesidad se han asociado con el riesgo de tener cáncer de ovario. Sin embargo, faltan investigaciones que correlacionen los problemas metabólicos con el riesgo de cáncer de ovario.
Objetivo: evaluar la asociación de riesgo entre DM2 y cáncer de ovario.
Metodología: estudio de casos y controles, razón 1:1. Los participantes con diagnóstico histopatológico de cáncer de ovario fueron los casos elegibles y los controles fueron elegidos por un muestreo de conveniencia de la base inicial de pacientes que se realizaron un eco ginecológico en un hospital de tercer nivel. La exposición de interés fue la DM2. Los OR se calcularon mediante el uso de regresión logística.
Resultados: se evaluó un total de 270 participantes (135 por brazo). En el grupo de mujeres con DM2 se observó un OR de 6,1 (IC 95% 2,47- 15,32) como factor de riesgo de cáncer de ovario. En el análisis multivariante ajustado por factores de confusión, la obesidad (OR 2,6; IC 95% 1,15-6,16) y la DM2 (OR 4,9; IC 95% 1,89 - 12,79) permanecieron como factores de riesgo independientes de cáncer de ovario.
Conclusión: en la muestra estudiada, la DM2 se comporta como un factor de riesgo de cáncer de ovario.