bluuebunny/crossref_metadata_2025 huggingface dataset:
Amidation of Aldehydes and Alcohols through α‐Iminonitriles and a Sequential Oxidative Three‐Component Strecker Reaction/Thio‐Michael Addition/Alumina‐Promoted Hydrolysis Process to Access β‐Mercaptoamides from Aldehydes, Amines, and Thiols
Authors: Gualtierotti Jean‐Baptiste , Schumacher Xavier , Fontaine Patrice , Masson Géraldine , Wang Qian , Zhu Jieping
Published: September 2012

Mild and general alumina‐promoted hydrolysis conditions for converting α‐iminonitriles into carboxamides have been developed. In combination with the oxidative three‐component Strecker reaction, the one‐pot direct amidation of aldehydes and alcohols is reported. Subsequently, an Yb(OTf)3‐catalyzed Michael addition of thiols to α,β‐unsaturated α‐iminonitriles is reported for the synthesis of β‐mercapto‐α‐iminonitriles. The successful integration of an oxidative Strecker reaction, thio‐Michael addition, and neutral‐alumina‐promoted hydrolysis of β‐mercapto‐α‐iminonitriles into a three‐component one‐pot process allowed us to develop the direct conversion of amines, aldehydes, and thiols into β‐mercaptoamides. All of these procedures were applicable to aromatic and aliphatic amines and aldehydes.
Molecular Description of the Propagation of Chirality from Molecules to Complex Systems: Different Mechanisms Controlled by Hydrophobic Interactions
Authors: Marinelli Fabrizio , Sorrenti Alessandro , Corvaglia Valentina , Leone Vanessa , Mancini Giovanna
Published: September 2012

In this work a combined theoretical and experimental approach was used to elucidate and describe at the molecular level the basic interactions that drive the transfer of the chiral information from chiral surfactant molecules to dye/surfactant assemblies. It was found that both hydrophobic interactions and relative concentrations strongly influence the chiroptical features of the heteroaggregates. In particular it was observed that, depending on the length of the surfactant hydrophobic chain, the chiral information is transferred to the dye by stabilizing an enantiomer either of a chiral conformer or of a chiral topological arrangement. These findings underline the role of hydrophobic interactions in the transfer of chirality and provide an example of the potential of in silico simulations for providing an accurate description of the process of chirality propagation.
Bispalladacycle‐Catalyzed Michael Addition of In Situ Formed Azlactones to Enones
Authors: Weber Manuel , Jautze Sascha , Frey Wolfgang , Peters René
Published: September 2012

The development and further evolution of the first catalytic asymmetric conjugate additions of azlactones as activated amino acid derivatives to enones is described. Whereas the first‐generation approach started from isolated azlactones, in the second‐generation approach the azlactones could be generated in situ starting from racemic N‐benzoylated amino acids. The third evolution stage could make use of racemic unprotected α‐amino acids to directly form highly enantioenriched and diastereomerically pure masked quaternary amino acid products bearing an additional tertiary stereocenter. The step‐economic transformations were accomplished by cooperative activation by using a robust planar chiral bis‐Pd catalyst, a Brønsted acid (HOAc or BzOH; Ac=acetyl, Bz=benzoyl), and a Brønsted base (NaOAc). In particular the second‐ and third‐generation approaches provide a rapid and divergent access to biologically interesting unnatural quaternary amino acid derivatives from inexpensive bulk chemicals. In that way highly enantioenriched acyclic α‐amino acids, α‐alkyl proline, and α‐alkyl pyroglutamic acid derivatives could be prepared in diastereomerically pure form. In addition, a unique way is presented to prepare diastereomerically pure bicyclic dipeptides in just two steps from unprotected tertiary α‐amino acids.
Copper‐Catalyzed Huisgen and Oxidative Huisgen Coupling Reactions Controlled by Polysiloxane‐Supported Amines (AFPs) for the Divergent Synthesis of Triazoles and Bistriazoles
Authors: Zheng Zhan‐Jiang , Ye Fei , Zheng Long‐Sheng , Yang Ke‐Fang , Lai Guo‐Qiao , Xu Li‐Wen
Published: September 2012

An interesting example of a divergent catalysis with a copper(I) and amine‐functional macromolecular polysiloxanes system was successfully presented in click chemistry. In this manuscript, we demonstrate the remarkable ability of the secondary amine‐functional polysiloxane to induce oxidative coupling in the copper‐mediated Huisgen reactions of azides and alkynes, thereby achieving good yields and selectivities. The click reactions mediated by a polysiloxane‐supported secondary amine allow the preparation of novel heterocyclic compounds, that is, bistriazoles. Comparably, it is also surprising that the use of a diamine‐functional polysiloxane as ligand led to a classic Huisgen [3+2] cycloaddition in excellent yields. From the results of the present amine‐functional polysiloxanes‐controlled Huisgen reaction or oxidative Huisgen coupling reaction to divergent products and the proposed mechanism, we suggested that the mononuclear bistriazole–copper complex stabilized and dispersed by the secondary amine‐functional polysiloxane was beneficial to prevalent the way to oxidative coupling.
ChemInform Abstract: Cd4Cu7As, the First Representative of a Fully Ordered, Orthorhombically Distorted MgCu2 Laves Phase.
Authors: Osters Oliver , Nilges Tom , Schoeneich Michael , Schmidt Peer , Rothballer Jan , Pielnhofer Florian , Weihrich Richard
Published: September 2012

The title compound, the first intermetallic compound in the Cu—Cd—As system, is synthesized by solid state reaction of a stoichiometric mixture of the elements (1000 °C, 63 h) and characterized by powder and single crystal XRD, DFT electronic structure calculations, and magnetic measurements.
ChemInform Abstract: Crystallographic and Magnetic Phase Transitions in the Layered Ruthenium Oxyarsenides TbRuAsO and DyRuAsO.
Authors: McGuire Michael A. , May Andrew F. , Sales Brian C.
Published: September 2012

The title compounds are characterized by powder XRD and magnetic, specific heat, electrical resistivity, and thermal conductivity measurements at and below room temperature.
ChemInform Abstract: Spectroscopic Assessment of Dy3+:LiLa(MoO4)2 Crystal as an Active Medium for All‐Solid‐State Direct Yellow‐Emitting Lasers.
Authors: Zhao Wang , Zhou Wei‐Wei , Wei Bo , Yu Yi , Wang Guo‐Fu , Du Jian‐Ming , Yu Hai‐Jun , Lv Zhao‐Cheng , Chen Yong‐Hong
Published: September 2012

The title crystal, grown by the Czochralski method, is characterized by absorption, excitation, and emission spectroscopy together with fluorescence decay measurements at room temperature.
ChemInform Abstract: Metastable 11 K Superconductor Na1‐yFe2‐xAs2
Authors: Friederichs Gina M. , Schellenberg Inga , Poettgen Rainer , Duppel Viola , Kienle Lorenz , Schmedt auf der Guenne Joern , Johrendt Dirk
Published: September 2012

The first metastable iron‐based superconductor of mean composition Na0.9Fe1.7As2 is prepared by topochemical deintercalation of Na+ ions from solid NaFeAs with iodine in THF at room temperature for 40 h.
ChemInform Abstract: Phase‐Change Materials Exhibiting Tristability: Interconverting Forms of Crystalline α‐, β‐, and Glassy K2ZnSn3S8.
Authors: Fard Zohreh Hassanzadeh , Kanatzidis Mercouri G.
Published: September 2012

The title compound is a phase‐change system exhibiting tristability.
ChemInform Abstract: A New Family of Mo‐Doped SrCoO3‐δ Perovskites for Application in Reversible Solid State Electrochemical Cells.
Authors: Aguadero A. , Perez‐Coll D. , Alonso J. A. , Skinner S. J. , Kilner J.
Published: September 2012

The introduction of Mo in SrCoO3‐δ to form SrCo0.95Mo0.05O3‐δ and SrCo0.9Mo0.1O3‐δ leads to a change from a hexagonal to a tetragonal (space group P4/mmm) perovskite structure at room temperature.
ChemInform Abstract: Synthesis of Faceted β‐SnWO4 Microcrystals with Enhanced Visible‐Light Photocatalytic Properties.
Authors: Ungelenk Jan , Feldmann Claus
Published: September 2012

Highly crystalline β‐SnWO4 truncated rhombic dodecahedrons with sharp edges and smooth faces are synthesized from a water‐in‐oil microemulsion loaded with a methanolic solution of SnCl2 and an aqueous solution of Na2WO4 (200 °C, 1 h, 50—60% yield).
ChemInform Abstract: Unexpected Disproportionation of Tetramethylethylenediamine‐Supported Perchlorodisilane Cl3SiSiCl3.
Authors: Tillmann Jan , Meyer‐Wegner Frank , Nadj Andor , Becker‐Baldus Johanna , Sinke Tanja , Bolte Michael , Holthausen Max C. , Wagner Matthias , Lerner Hans‐Wolfram
Published: September 2012

Reactions of (I) with tetramethylethylenediamine are studied and the crystal structures of (II), (III), (IV), and (VI) are determined by single crystal XRD.
ChemInform Abstract: Cation Size Effect on the Framework Structure in a Series of New Alkali‐Metal Indium Selenites, AIn(SeO3)2 (A: Na, K. Rb, and Cs).
Authors: Lee Dong Woo , Kim Saet Byeol , Ok Kang Min
Published: September 2012

Crystals of MIn(SeO3)2 with M: Na, K are synthesized by solid state reaction of MInO2 and SeO2 (650 °C, 48 h).
ChemInform Abstract: Single‐Crystal Structures, Optical Absorptions, and Electronic Distributions of Thorium Oxychalcogenides ThOQ (Q: S, Se, Te).
Authors: Koscielski Lukasz A. , Ringe Emilie , Van Duyne Richard P. , Ellis Donald E. , Ibers James A.
Published: September 2012

Compounds (III), (V), and (VII), obtained as side products in multiple reactions, are characterized by single crystal XRD, optical absorption spectroscopy, and DFT computations.
ChemInform Abstract: {Sn9[Si(SiMe3)3]2}2‐: A Metalloid Tin Cluster Compound with a Sn9 Core of Oxidation State Zero.
Authors: Schrenk Claudio , Winter Florian , Poettgen Rainer , Schnepf Andreas
Published: September 2012

[Li(tmeda)2]2{Sn9 [Si(SiMe3)3]2} (tmeda: tetramethylethylenediamine) is synthesized from a mixture of SnCl (obtained by reaction of Sn with HCl at 1240 °C) and LiSi(SiMe3)3 at ‐78 °C followed by slow warming to room temperature and addition of TMEDA (11% yield).
ChemInform Abstract: Synthesis and Characterization of Li11Nd18Fe4O39‐δ.
Authors: Chen Yao‐Chang , Reeves‐McLaren Nik , Bingham Paul A. , Forder Susan D. , West Anthony R.
Published: September 2012

The title compound is prepared by solid state reaction of pressed pellets of Li2CO3, Nd2O3, and Fe(C2O4) covered with a powder of the same composition to avoid Li loss (700 °C, 12 h and 950 °C, 12—24 h).
ChemInform Abstract: Synthesis and Characterization of Sr2Cu(W1‐xMox)O6: A Quasi‐Two‐Dimensional Magnetic System.
Authors: Vasala S. , Cheng J.‐G. , Yamauchi H. , Goodenough J. B. , Karppinen M.
Published: September 2012

The title double‐perovskite compounds (x = 0.0—1.0) are synthesized by reaction of SrCO3, CuO, WO3, and MO3 at ambient pressure for 0 ≤ x ≤ 0.6 (air, 900 °C for 12 h and 1000 °C for 24 h) and at high pressure for 0.7 ≤ x ≤ 1.0 (1.
ChemInform Abstract: Solvent‐Mediated Room Temperature Synthesis of Highly Crystalline Cu9S5 (Cu1.8S), CuSe, PbS, and PbSe from Their Elements.
Authors: Kumar Prashant , Gusain Meenakshi , Nagarajan Rajamani
Published: September 2012

The title compounds are synthesized from mixtures of the elements in 2‐mercaptoethanol as solvent (25 °C, 24 h).
ChemInform Abstract: Enantioselective Friedel—Crafts Reactions in Water Catalyzed by a Human Telomeric G‐Quadruplex DNA Metalloenzyme.
Authors: Wang Changhao , Li Yinghao , Jia Guoqing , Liu Yan , Lu Shengmei , Li Can
Published: September 2012

The enantioselectivity as well as the absolute configuration of the product are sensitive to the DNA sequence.
ChemInform Abstract: Recoverable Organorhodium‐Functionalized Polyhedral Oligomeric Silsesquioxane: A Bifunctional Heterogeneous Catalyst for Asymmetric Transfer Hydrogenation of Aromatic Ketones in Aqueous Medium.
Authors: Tang Shuang , Jin Ronghua , Zhang Huaisheng , Yao Hui , Zhuang Jinglan , Liu Guohua , Li Hexing
Published: September 2012

The title catalyst exhibits excellent enantioselectivity and can be easily recovered and reused repeatedly without loss of activity.
ChemInform Abstract: DNA‐Based Catalytic Enantioselective Intermolecular oxa‐Michael Addition Reactions.
Authors: Megens Rik P. , Roelfes Gerard
Published: September 2012

Up to 86% e.e.
ChemInform Abstract: Enantioselective Catalysis with a Chiral, Phosphane‐Containing PMO Material.
Authors: Seki Tomohiro , McEleney Kevin , Crudden Cathleen M.
Published: September 2012

A periodic mesoporous organosilica functionalized with BINAP is synthesized which shows high catalytic activity and enantioselectivity in asymmetric and transfer hydrogenation reactions.
ChemInform Abstract: Catalytic Enantioselective Chlorination of Cyclic β‐Keto Esters in the Presence of Chiral Pd(II) Complexes.
Authors: Kang Young Ku , Kim Hee Hun , Koh Kwang Oh , Kim Dae Young
Published: September 2012

An efficient enantioselective electrophilic α‐chlorination of various cyclic β‐keto esters in the presence of a dicationic palladium complex is developed.
ChemInform Abstract: Allylic Activation Across an Ir—Sn Heterobimetallic Catalyst: Nucleophilic Substitution and Disproportionation of Allylic Alcohol.
Authors: Chatterjee Paresh Nath , Roy Sujit
Published: September 2012

A variety of cinnamic alcohol derivatives undergo substitution of the free hydroxyl group by O‐, N‐, S‐ or C‐nucleophiles in the presence of a bimetallic Ir—Sn catalyst.
ChemInform Abstract: Pd‐Complex‐Bound Amino Acid‐Based Supramolecular Gel Catalyst for Intramolecular Addition—Cyclization of Alkynoic Acids in Water.
Authors: Ogata Kazuki , Sasano Daisuke , Yokoi Tomoya , Isozaki Katsuhiro , Seike Hirofumi , Takaya Hikaru , Nakamura Masaharu
Published: September 2012

A xerogel derived from the supramolecular gel of NHC‐pincer Pd‐complex‐bound norvaline shows high catalytic activity for the intramolecular addition‐cyclization of alkynoic acid and phenol derivatives in water furnishing ene‐lactones in good to excellent yields.
ChemInform Abstract: Catalytic Enantioselective Halolactonization of Enynes and Alkenes.
Authors: Zhang Wei , Liu Na , Schienebeck Casi M. , Decloux Kyle , Zheng Suqing , Werness Jenny B. , Tang Weiping
Published: September 2012

Two novel catalysts are successfully applied to the title reactions.
ChemInform Abstract: Manganese(III)‐Mediated Radical Cyclizations for the (Z)‐Selective Synthesis of exo‐Alkylidene Pyrrolidinones and Pyrrolidines.
Authors: Keane Harriet A. , Hess Wilfried , Burton Jonathan W.
Published: September 2012

The radical cyclization of internal alkynes (V) and (VIII) proceeds readily in the presence of manganese triacetate to afford a (E)/(Z)‐mixture of exo‐alkylidene cyclic products (VI)/(VII) and (IX)/(X).
ChemInform Abstract: Catalytic Asymmetric Synthesis of Nitrocyclopropane Carboxylates.
Authors: Moreau Benoit , Alberico Dino , Lindsay Vincent N. G. , Charette Andre B.
Published: September 2012

The cyclopropanation of an iodonium ylide derived from methyl nitroacetate (II) in the presence of chiral copper complexes leads to a variety of trans‐nitrocyclopronane carboxylates such as (III), (XI), (XIV), or (XVI) with up to 95% diastereoselectivity and up to 98% e.e.
ChemInform Abstract: Oxidation of Secondary Benzylic Alcohols to Ketones and Benzylic Oxygenation of Alkylarenes with Hydrogen Peroxide in Presence of Activated Carbon.
Authors: Nishida Shunsuke , Hayashi Masahiko
Published: September 2012

The method is successfully applied to various substrate types.
ChemInform Abstract: Cu(0) Nanoparticle Catalyzed Efficient Reductive Cleavage of Isoxazoline, Carbonyl Azide and Domino Cyclization in Water Medium.
Authors: Gayen Krishnanka S. , Sengupta Tista , Saima Yasmin , Das Adita , Maiti Dilip K. , Mitra Atanu
Published: September 2012

Small Cu(0) nanoparticles fabricated in situ exhibit high catalytic reduction properties towards the heteroatomic cleavage of N—O bonds, homoatomic N—N bonds and domino cyclizations to afford 2‐hydroxy‐ketones (II), primary amides (V) and pyrroline‐5‐ones (III).
ChemInform Abstract: Magnetic Nanoparticles Entrapped in Siliceous Mesocellular Foam: A New Catalyst Support.
Authors: Lee Su Seong , Riduan Siti Nurhanna , Erathodiyil Nandanan , Lim Jaehong , Cheong Jian Liang , Cha Junhoe , Han Yu , Ying Jackie Y.
Published: September 2012

A new catalyst support is prepared by immobilization of γ‐Fe2O3 nanoparticles in the cage‐like pores of siliceous mesocellular foam.
ChemInform Abstract: Highly Efficient and Simple Catalytic System for the N‐Arylation of Some Hindered Aza‐Heterocycles in Water.
Authors: Mukhopadhyay Chhanda , Tapaswi Pradip Kumar
Published: September 2012

Optimum reaction conditions are examined for the N‐arylation of some aza‐heterocycles with aryl iodides or bromides using basic copper carbonate as catalyst.
ChemInform Abstract: Base‐Mediated Selective Synthesis of Diversely Substituted N‐Heterocyclic Enamines and Enaminones by the Hydroamination of Alkynes.
Authors: Joshi Megha , Patel Monika , Tiwari Rakesh , Verma Akhilesh K.
Published: September 2012

A broad range of N‐alkenyl‐substituted indoles, pyrroles, and imidazoles are prepared from the corresponding heterocycles and terminal alkynes, internal alkynes, or dialkynes under metal‐ and ligand‐free conditions using catalytic or stoichiometric amounts of KOH or Cs2CO3.
ChemInform Abstract: Practical Procedure for Copper(I)‐Catalyzed Allylic Boryl Substitution with Stoichiometric Alkoxide Base.
Authors: Ito Hajime , Miya Takanori , Sawamura Masaya
Published: September 2012

A highly versatile method is given for the synthesis of allylboronates including those with terminal and internal allylic systems, cyclic structures, and functional groups.
ChemInform Abstract: Metal‐Free Arylation of Benzene and Pyridine Promoted by Amino‐Linked Nitrogen Heterocyclic Carbenes.
Authors: Chen Wen‐Ching , Hsu Yu‐Chen , Shih Wei‐Chun , Lee Ching‐Yu , Chuang Wen‐Han , Tsai Yi‐Fang , Chen Peter Ping‐Yu , Ong Tiow‐Gan
Published: September 2012

An amino‐linked nitrogen heterocyclic carbene mediates the carbon—carbon coupling reaction through direct C—H functionalization of benzene (II) and pyridine (IV) with aryl iodides (I) in the absence of a metal catalyst.
ChemInform Abstract: Metal‐Free Pinnick‐Type Oxidative Amidation of Aldehydes.
Authors: Goh Kien Soon , Tan Choon‐Hong
Published: September 2012

The method is applicable to a large variety of aldehydes and amines, including optically active ones.
ChemInform Abstract: Glycerol as a Biodegradable and Reusable Promoting Medium for the Catalyst‐Free One‐Pot Three‐Component Synthesis of 4H‐Pyrans.
Authors: Safaei Hamid Reza , Shekouhy Mohsen , Rahmanpur Sudabeh , Shirinfeshan Athar
Published: September 2012

The described method not only offers substantial improvements in the reaction rates and yields, but also avoids the use of additional catalysts or solvents.
ChemInform Abstract: TBD Catalysis with Dimethyl Carbonate: A Fruitful and Sustainable Alliance.
Authors: Mutlu Hatice , Ruiz Johal , Solleder Susanne C. , Meier Michael A. R.
Published: September 2012

The paper describes the use of 1,5,7‐triazabicyclo[4.4.0]dec‐5‐ene (TBD) an organocatalyst, in combination with dimethylcarbonate (II), allowing the synthesis of unsymmetrical carbonates (III) in high yields under optimized conditions.
ChemInform Abstract: Gold(I)‐Catalyzed Cycloisomerization of 1,6‐Cyclopropene‐enes.
Authors: Miege Frederic , Meyer Christophe , Cossy Janine
Published: September 2012

A detailed and extended account on previously published studies is presented.
ChemInform Abstract: One‐Pot Synthesis of Succinimidyl‐4‐(N‐maleimidomethyl)cyclohexane‐1‐carboxylate (SMCC).
Authors: Leonard Nicholas M. , Brunckova Jarmila
Published: September 2012

An improved one‐pot synthesis of SMCC (IV), a valuable heterobifunctional linker in pharmaceutical chemistry, is described.
ChemInform Abstract: A Silver‐Catalyzed Spirocyclization of Alkynyl Silyl Enol Ethers.
Authors: Schaefer Christian , Miesch Michel , Miesch Laurence
Published: September 2012

The cycloisomerization of alkynyl silyl enol ethers proceeds in the presence of a silver catalyst in dependence on the solvent used.
ChemInform Abstract: Pd‐Catalyzed Arylation of Chlorotrifluoroethylene Using Arylboronic Acids.
Authors: Yamamoto Tetsuya , Yamakawa Tetsu
Published: September 2012

The transformation provides a wide range of trifluorostyrene derivatives in good to high yields.
ChemInform Abstract: One‐Step Synthesis of (1‐Iodovinyl) Arenes from Trimethylsilyl Ethynylarene Through Iodotrimethylsilane‐Mediated Hydroiodation.
Authors: Sato Akihiro H. , Mihara Shigenori , Iwasawa Tetsuo
Published: September 2012

A simple protocol is developed for the iodotrimethylsilane mediated hydroiodination of trimethylsilylethynylarenes and ethynylarenes to give the corresponding (1‐iodovinyl)arenes.
ChemInform Abstract: Aromatic Substitution in Ball Mills: Formation of Aryl Chlorides and Bromides Using Potassium Peroxomonosulfate and NaX.
Authors: Schmidt Robert , Stolle Achim , Ondruschka Bernd
Published: September 2012

Aryl chlorides and bromides are formed from arenes in a ball mill using Oxone and the corresponding sodium halide as oxidant and halogen source, respectively.
ChemInform Abstract: Highly Regioselective Aminobromination of α,β‐Unsaturated Nitro Compounds with Benzyl Carbamate/N‐Bromosuccinimide as Nitrogen/Bromine Source.
Authors: Ji Xiaoyun , Duan Zhiqiang , Qian Yu , Han Jianlin , Li Guigen , Pan Yi
Published: September 2012

The new catalytic system, developed for the preparation of dibrominated nitro compounds, tolerates a wide range of aromatic, as well as heterocyclic and aliphatic substrates.
ChemInform Abstract: Copper(I)‐Catalyzed Deacetylenative Cross‐Coupling Reaction of Terminal Alkynes with Propargylic Amines via C(sp)—C(sp3) Bond Cleavage.
Authors: Kim Yongeun , Nakamura Hiroyuki
Published: September 2012

Optimized conditions allow the preparation of a broad spectrum of substituted propargylic amines bearing various functionalities.
ChemInform Abstract: Decarboxylative Etherification of Aromatic Carboxylic Acids.
Authors: Bhadra Sukalyan , Dzik Wojciech I. , Goossen Lukas J.
Published: September 2012

The present new procedure to synthesize aryl ethers is the first example of Chan—Evans—Lam‐type couplings of aromatic carboxylic acids.
ChemInform Abstract: RuCl3‐DCHA Catalyst System: A Selective Aerobic Oxidation of Primary Benzylic Alcohols under Mild Conditions.
Authors: Yu Kaihui , Ye Dongnai , Shu Lei , Zhang Shiyong , Hu Qiaosheng , Liu Liangxian
Published: September 2012

The RuCl3‐catalyzed aerobic oxidation of a diversity of benzylic alcohols in the presence of dicyclohexylamine proceeds smoothly to afford aldehydes (II) and ketones (IV).
ChemInform Abstract: A Formal Method for the De‐N,N‐dialkylation of Sommelet—Hauser Rearrangement Products.
Authors: Tayama Eiji , Sato Ryota , Takedachi Keisuke , Iwamoto Hajime , Hasegawa Eietsu
Published: September 2012

The present method furnishes valuable intermediates for preparation of α‐aryl‐α‐amino or α‐aryl‐β‐amino carboxylic acid derivatives.
ChemInform Abstract: o‐Benzenedisulfonimide and Its Chiral Derivative as Broensted Acids Catalysts for One‐Pot Three‐Component Strecker Reaction. Synthetic and Mechanistic Aspects.
Authors: Barbero Margherita , Cadamuro Silvano , Dughera Stefano , Ghigo Giovanni
Published: September 2012

A new application of the recyclable and reusable catalyst (for five times) is presented for the very simple, efficient, and green title reaction, which includes an easy work‐up procedure.
ChemInform Abstract: Simple Chiral Sulfonamide Primary Amine Catalyzed Highly Enantioselective Michael Addition of Malonates to Enones.
Authors: Luo Chunhua , Jin Yu , Du Da‐Ming
Published: September 2012

The sulfonamide catalyst, which is readily available from chiral 1,2‐diamine, is successfully applied to the cheap and facile title reaction.
ChemInform Abstract: Reaction Discovery by Using a Sandwich Immunoassay.
Authors: Quinton Julia , Kolodych Sergii , Chaumonet Manon , Bevilacqua Valentina , Nevers Marie‐Claire , Volland Herve , Gabillet Sandra , Thuery Pierre , Creminon Christophe , Taran Frederic
Published: September 2012

Two novel reactions, a copper‐catalyzed desulfuration of thioureas leading to isoureas and a copper‐promoted cyclization reaction leading to thiazoles from alkynes and N‐hydroxy thioureas are discovered using a sandwich immunoassay screening technique which allows to measure at least 1000 reaction yields per day by a single operator.
ChemInform Abstract: Metal‐Free Synthesis of Allylic Amines by Cross‐Dehydrogenative‐Coupling of 1,3‐Diarylpropenes with Anilines and Amides under Mild Conditions.
Authors: Wang Zhiming , Mo Hanjie , Cheng Dongping , Bao Weiliang
Published: September 2012

A highly facile, efficient, mild, and new method for the synthesis of the title amines is presented.
ChemInform Abstract: Palladium Nanoparticles Supported on a Poly(N‐vinyl‐2‐pyrrolidone)‐Modified Mesoporous Carbon Nanocage as a Novel Heterogeneous Catalyst for the Heck Reaction in Water.
Authors: Kalbasi Roozbeh Javad , Mosaddegh Neda , Abbaspourrad Alireza
Published: September 2012

The title Pd‐catalyst is successfully applied to the Heck reaction of aromatic aryl halides and styrene to give E‐stilbenes.
ChemInform Abstract: Pd‐Catalyzed Cross‐Coupling of Aryl Carboxylic Acids with Propiophenones Through a Combination of Decarboxylation and Dehydrogenation.
Authors: Zhou Jun , Wu Ge , Zhang Min , Jie Xiaoming , Su Weiping
Published: September 2012

The reaction (II) to propiophenones proceeds under adjusted conditions to give chalcones (III) and (V) tolerating a variety of functional groups.
ChemInform Abstract: One‐Pot Solvent‐Free Sonochemical Synthesis of 1‐Amidoalkyl‐2‐naphthols.
Authors: Puri Saurabh , Kaur Balbir , Parmar Anupama , Kumar Harish
Published: September 2012

A general, efficient and eco‐friendly procedure for the synthesis of 1‐amidoalkylnaphthols (IV) (12 examples) via a ultrasound‐mediated three‐component reaction is given.
ChemInform Abstract: Microwave Assisted Synthesis of Spirocyclic Pyrrolidines — σ1 Receptor Ligands with Modified Benzene‐N‐distance.
Authors: Jasper Annemarie , Schepmann Dirk , Lehmkuhl Kirstin , Vela Jose Miguel , Buschmann Helmut , Holent Joerg , Wuensch Bernhard
Published: September 2012

Spirocyclic benzofurans (IV), (V) and (VII) as well as the corresponding benzopyrans are produced and tested as 1:1 mixtures of cis and trans diastereomers.
ChemInform Abstract: Catalytic Asymmetric Epoxidation of 2‐Cyclopentenones.
Authors: Lee Anna , Reisinger Corinna M. , List Benjamin
Published: September 2012

A highly efficient asymmetric epoxidation of cyclopentenones is presented.
ChemInform Abstract: Copper Bis(oxazolines) as Catalysts for Stereoselective Aziridination of Styrenes with N‐Tosyloxycarbamates.
Authors: Lebel Helene , Parmentier Michael , Leogane Olivier , Ross Karen , Spitz Cedric
Published: September 2012

The aziridination of styrenes (I) carrying electron.withdrawing groups with chiral N‐tosyloxycarbamate (II) gives the aziridines (III) with good to excellent diastereoselectivity.
ChemInform Abstract: Zinc or Indium‐Mediated Barbier‐Type Allylation of Aldehydes with 3‐Bromomethyl‐5H‐furan‐2‐one in Aqueous Media: An Efficient Synthesis Method for α‐Methylene‐γ‐butyrolactone.
Authors: Gao Yu‐Zhe , Wang Xue , Sun Li‐Dong , Xie Long‐Guan , Xu Xiao‐Hua
Published: September 2012

Mild and convenient methods for the diastereoselective synthesis of the compounds (III) and (V) are developed.
ChemInform Abstract: Intramolecular Etherification of Five‐Membered Cyclic Carbonates Bearing Hydroxyalkyl Groups.
Authors: Tomczyk Karolina M. , Gunka Piotr A. , Parzuchowski Pawel G. , Zachara Janusz , Rokicki Gabriel
Published: September 2012

Diols with vicinal hydroxyl groups easily form five‐membered cyclic carbonates (III) in high yields with dimethyl carbonate (II) in the presence of a alkaline catalyst.
ChemInform Abstract: Simple, Convenient Method for the Synthesis of Substituted Furan‐2(5H)‐one Derivatives Using Tin(II) Chloride.
Authors: Nagarapu Lingaiah , Kumar U. Nikhil , Upendra P. , Bantu Rajashaker
Published: September 2012

A simple and efficient tin‐catalyzed three‐component reaction of DMAD (I) with aromatic aldehydes and amines is presented.
ChemInform Abstract: A Highly Efficient One‐Pot Reaction of 2‐(gem‐Dibromovinyl)phenols(thiophenols) with K4Fe(CN)6 to 2‐Cyanobenzofurans(thiophenes).
Authors: Zhou Wei , Chen Wei , Wang Lei
Published: September 2012

The novel title reaction is reported under mild and low‐toxic reactions conditions.
ChemInform Abstract: Gold(I)‐Catalyzed Cyclization of 2‐(1‐Alkynyl)‐alk‐2‐en‐1‐one Oximes: A Facile Access to Highly Substituted N‐Alkoxypyrroles.
Authors: Zhang Mei , Zhang Junliang
Published: September 2012

An efficient, mild, and atom‐economic route to substituted N‐alkoxypyrroles uses various nucleophiles in the title reaction.
ChemInform Abstract: An Insight into Solvent‐Free Diimide Porphyrin Reduction: A Versatile Approach for meso‐Aryl Hydroporphyrin Synthesis.
Authors: Pereira Mariette M. , Abreu Artur R. , Goncalves Nuno P. F. , Calvete Mario J. F. , Simoes Ana V. C. , Monteiro Carlos J. P. , Arnaut Luis G. , Eusebio Maria Ermelinda , Canotilho Joao
Published: September 2012

The preparation of meso‐aryl hydroporphyrins, namely chlorins (II) and bacteriochlorins (IV), proceeds via reduction of porphyrins (I) and (III) with diimide in the absence of solvents and bases.
ChemInform Abstract: An Acid‐Catalyzed Hydroamination Approach to Isoindolines.
Authors: Henderson Laura , Knight David W. , Williams Andrew C.
Published: September 2012

In most cases, TfOH as the catalyst gives higher yields than to concentrated sulfuric acid.
ChemInform Abstract: Synthesis of Amino‐Substituted Indoles Using the Bartoli Reaction.
Authors: Wylie Laura , Innocenti Paolo , Whelligan Daniel K. , Hoelder Swen
Published: September 2012

Nitroanilines are used for the first time as substrates in the Bartoli reaction, providing a new method for preparation of aminoindoles.
ChemInform Abstract: PEG‐SO3H as a Catalyst for the Preparation of Bisindolyl and Trisindolyl Methanes in Aqueous Media.
Authors: Rani V. Jhansi , Vani K. Veena , Rao C. Venkata
Published: September 2012

Advantages of the presented method are operational simplicity and remarkably short reaction times.
ChemInform Abstract: Synthesis and Photoluminescent Properties of New Cationic Carbazole‐Containing Luminophores.
Authors: Baran A. , Plotniece A. , Sobolev A. , Vigante B. , Gosteva M. , Olkhovik V.
Published: September 2012

8 Title compounds of type (I) or (II) are prepared and their photoluminescent properties are measured.
ChemInform Abstract: Electron‐Poor N‐Substituted Imide‐Fused Corannulenes.
Authors: Schmidt Bernd M. , Topolinski Berit , Roesch Philipp , Lentz Dieter
Published: September 2012

Novel corannulenes (V) are obtained by Wohl—Ziegler bromination of tetramethylfluoranthenes (IV) followed by a nickel‐mediated intramolecular coupling reaction.
ChemInform Abstract: Tandem Knoevenagel—Michael Reaction of 1‐Phenyl‐3‐methyl‐5‐pyrazolone with Aldehydes Using 3‐Aminopropylated Silica Gel as an Efficient and Reusable Heterogeneous Catalyst.
Authors: Sobhani Sara , Hasaninejad Ali‐Reza , Maleki Mahdi Faal , Parizi Zahra Pakdin
Published: September 2012

Aminopropylated silica gel is shown to be an efficient heterogeneous catalyst for the tandem Knoevenagel—Michael reaction of pyrazolone (I) with various aldehydes.
ChemInform Abstract: Efficient Catalytic Cyclizations of Three and Two Imine Assemblies: Direct Access to Tetrahydroimidazo[1,5‐c]imidazol‐7‐ones and Imidazoles.
Authors: Saima Yasmin , Khamarui Saikat , Gayen Krishnanka S. , Pandit Palash , Maiti Dilip K.
Published: September 2012

Treatment of in situ prepared aldimines with proline leads diastereoselectively to tetrahydroimidazo[1,5‐c]imidazol‐7‐ones (III).
ChemInform Abstract: Synthesis and Synthetic Applications of 1‐Aryl‐2‐alkyl‐4,5‐dihydro‐1H‐imidazoles.
Authors: Reverdito Ana M. , Perillo Isabel A. , Salerno Alejandra
Published: September 2012

The microwave‐assisted cyclocondensation of N‐aryl‐N′‐acyldiamines (I) gives easy access to title dihydroimidazoles (II).
ChemInform Abstract: Functionalized Orthoesters as Powerful Building Blocks for the Efficient Preparation of Heteroaromatic Bicycles.
Authors: Bastug Gulluzar , Eviolitte Christophe , Marko Istvan E.
Published: September 2012

Treatment of 2‐aminothiophenols, 2‐aminophenols, and benzene‐1,2‐diamines with functionalized orthoesters allows an efficient access to the title scaffolds.
ChemInform Abstract: Palladium‐Catalyzed Selective C—H Benzylation Towards Functionalized Azoles with a Quaternary Carbon Center.
Authors: Xie Pan , Huang Hanmin , Xie Yinjun , Guo Shengmei , Xia Chungu
Published: September 2012

The method efficiently generates a wide range of tribenzylated azoles (III) with a quaternary carbon center.
ChemInform Abstract: Isoxazolo(aza)naphthoquinones: A New Class of Cytotoxic Hsp90 Inhibitors.
Authors: Dallavalle Sabrina , et al. et al.
Published: September 2012

Cycloaddition of in situ prepared benzonitriloxides to quinones is exploited for the synthesis of substituted isoxazolo‐fused naphthoquinones.
ChemInform Abstract: Discovery, Design and Synthesis of Y‐Shaped Peroxisome Proliferator‐Activated Receptor δ Agonists as Potent anti‐Obesity Agents in vivo.
Authors: Chin Jungwook , et al. et al.
Published: September 2012

Novel Y‐shaped PPARδ ligands are synthesized by combination of a known ligand and a marine natural product using automatic docking experiments.
ChemInform Abstract: Easy Access to 2‐Alkyl and 2‐Arylthiazolines Using a Modified Heteropolyacid Catalysis: Application to the Synthesis of Bacillamide A.
Authors: Fache F. , Cros F. , Piva O. , Lefebvre F.
Published: September 2012

A straightforward access to 2‐alkyl and 2‐arylthiazoles (III) by condensation of β‐aminothiols and nitriles, catalyzed by tungstophosphoric acid under microwave irradiation, is described.
ChemInform Abstract: Synthesis and Antitumor Evaluation of Novel Benzo[d]pyrrolo[2,1‐b]thiazole Derivatives.
Authors: Lee Te‐Chang , et al. et al.
Published: September 2012

A variety of benzopyrrolothiazole derivatives (VII),(IX), and (XI) is studied for anticancer activity against various human cancer cell lines.
ChemInform Abstract: Iron‐Catalyzed Arylation of Benzoazoles with Aromatic Aldehydes Using Oxygen as Oxidant.
Authors: Liu Saiwen , Chen Ru , Guo Xiangyu , Yang Huiqiong , Deng Guojun , Li Chao‐Jun
Published: September 2012

One aliphatic aldehyde, e.g. (IIb), is also included which gives the corresponding product (IIIb) in moderate yield.
ChemInform Abstract: Reactions of 4‐Phenyl‐1,2,4‐triazoline‐3,5‐dione with 2‐Pyrazolines.
Authors: Novikov R. A. , Korolev V. A. , Tomilov Yu. V.
Published: September 2012

The mechanisms behind the reactions of 4‐phenyl‐1,2,4‐triazoline‐3,5‐dione (PTAD) with both 1‐unsubstituted and 1‐substituted 2‐pyrazolines are discussed.
ChemInform Abstract: Synthesis of 3‐Nitramino‐4‐(1H‐1,2,3‐triazol‐1‐yl)‐1,2,5‐oxadiazoles and Their Salts.
Authors: Rozhkov V. Yu. , Batog L. V. , Struchkova M. I.
Published: September 2012

Triazolylfurazans bearing a primary nitramino group attached to the furazan ring, e.g. (II), are prepared for the first time.
ChemInform Abstract: ZnO as an Effective and Reusable Heterogeneous Catalyst for the Synthesis of Arylaminotetrazoles.
Authors: Habibi Davood , Nasrollahzadeh Mahmoud
Published: September 2012

The formation of either 1‐aryl‐5‐amino‐1H‐tetrazoles (II) or 5‐arylamino‐1H‐tetrazoles (IV) from the ZnO‐catalyzed reaction of arylcyanamides and sodium azide is strongly influenced by the electronic nature of aryl substituents.
ChemInform Abstract: A Novel Organocatalytic Multi‐Component Reaction: An Efficient Synthesis of Polysubstituted Pyrano‐Fused Spirooxindoles.
Authors: Tisseh Zeinab Noroozi , Ahmadi Fereshteh , Dabiri Minoo , Khavasi Hamid Reza , Bazgir Ayoob
Published: September 2012

A simple protocol is presented for the three‐component reaction of isatins, malononitrile and acetylene derivatives to give the title compounds (IV).
ChemInform Abstract: Diastereoselective 1,3‐Dipolar Cycloaddition of Pyrylium Ylides with Chiral Enamides.
Authors: Tchabanenko Kirill , Sloan Colleen , Bunetel Yves‐Mael , Mullen Philip
Published: September 2012

The first example of the use of amides as alkene in the title reaction is demonstrated.
ChemInform Abstract: A Tandem Olefin Migration and Prins Cyclization Using Cu(OTf)2—Bisphosphine Complexes: An Improved Synthesis of Functionalized Tetrahydropyrans.
Authors: Ghosh Arun K. , Nicponski Daniel R. , Kass Jorden
Published: September 2012

The scope of the Cu(OTf)2—bisphoshine catalyzed tandem olefin migration and Prins cyclization of the hexenol (I) with aldehydes is investigated using a quite stable bisphoshine ligand with low air‐sensitivity.
ChemInform Abstract: Me3SiI‐Promoted Reaction of Salicylic Aldehydes with Ketones: A Facile Way to Construct Benzopyranic [2,3‐b]Ketals and Spiroketals.
Authors: Wang Feijun , Qu Mingliang , Lu Xi , Chen Feng , Chen Feng , Shi Min
Published: September 2012

A highly versatile one‐pot methodology for the synthesis of heteroannular ketals and spiroketals is described.
ChemInform Abstract: Borderline Metal‐Catalyzed Carboarylation of Alkynylarenes Using N,O‐Acetals.
Authors: Komeyama Kimihiro , Yamada Takahiro , Igawa Ryoichi , Takaki Ken
Published: September 2012

The carboarylation of alkynylarenes with N‐acyliminium ions, generated from N,O‐acetals, is catalyzed by Bi(O‐Tf)3 or Fe(O‐Tf)3.
ChemInform Abstract: Facile Syntheses of 2‐Substituted 3‐Cyanochromones.
Authors: Levchenko K. S. , Semenova I. S. , Yarovenko V. N. , Shmelin P. S. , Krayushkin M. M.
Published: September 2012

Based on the condensation of carboxylic acid chlorides or anhydrides with 3‐(2‐hydroxyphenyl)‐3‐oxopropionitrile (I), a general synthesis of the title compounds (III) is described.
ChemInform Abstract: Effective Synthesis of tert‐Butyl‐Substituted 3‐Carboxy Coumarins in Water Using TEBAC as Catalyst.
Authors: Li Yang , Gao Wentao
Published: September 2012

Hitherto unreported hydrophobically substituted 3‐carboxycoumarin derivatives (III) are synthesized by modifying a known method through use of benzyltriethylammonium chloride as catalyst.
ChemInform Abstract: Efficient Synthesis of 12‐Aryl‐8,9,10,12‐tetrahydrobenzo[a]xanthen‐11‐one Derivatives Catalyzed by p‐Dodecylbenzenesulfonic Acid in Aqueous Media under Ultrasound Irradiation.
Authors: Li Ji‐Tai , Li Yan‐Wei , Song Ya‐Li
Published: September 2012

Dodecylbenzenesulfonic acid acts as both Broensted acid and phase‐transfer catalyst.
ChemInform Abstract: Synthesis of 3‐Aroyl‐4‐hydroxy‐4‐arylpiperidine Derivatives by DBU‐Catalyzed Reactions of Amines with Vinyl Ketones.
Authors: Liu Xiaodong , chen Qiao , Li Wenyi , Wang Rui
Published: September 2012

A highly efficient cascade reaction of primary amines, generally sulfonamides, with aryl vinyl ketones results in the diastereoselective formation of functionalized piperidines, key structures of natural products and drugs.
ChemInform Abstract: Solvent‐ and Catalyst‐Free Synthesis of New Hydroxylated Trisubstituted Pyridines under Microwave Irradiation.
Authors: Yin Guodong , Liu Qiong , Ma Junrui , She Nengfang
Published: September 2012

The expected products are obtained through a simplified purification procedure without protection of the hydroxyl group.
ChemInform Abstract: K2CO3‐Mediated, One‐Pot, Multicomponent Synthesis of Medicinally Potent Pyridine and Chromeno[2,3‐b]pyridine Scaffolds.
Authors: Mishra Sarita , Ghosh Rina
Published: September 2012

An efficient potassium carbonate‐catalyzed three‐component reaction of malononitrile (I) with a wide variety of aldehydes (II), (V), (VII) and thiols (III), (VIII) is presented to afford dihydropyrimidine intermediates which are aromatized with potassium permanganate.
ChemInform Abstract: Asymmetric Synthesis of 2‐Alkyl‐substituted Tetrahydroquinolines by an Enantioselective Aza‐Michael Reaction.
Authors: Taylor Laura L. , Goldberg Frederick W. , Hii King Kuok
Published: September 2012

An enantioselective Pd‐catalyzed aza‐Michael reaction is used as the key step in the preparation of Galipea alkaloids angustureine, galipeine and cuspareine (V).
ChemInform Abstract: Efficient Synthesis of Substituted Quinolines Through Intramolecular Addition of Aryl Anion to Carbonyl Carbon.
Authors: Kobayashi Yuichi , Igarashi Junji , Feng Chao , Tojo Toshifumi
Published: September 2012

The convenient three‐step synthesis of quinolines is based on intramolecular cyclization of N‐Michael addition products (III) followed by an acetyl chloride mediated dehydration‐deprotection‐dehydrogenation sequence.
ChemInform Abstract: Synthesis and Biological Studies of Some New Acrylic Acid Ethyl Esters of Quinolinone.
Authors: Kalkhambkar Rajesh G. , Aridoss G. , Kulkarni Geeta M. , Bapset R. M. , Kadakol J. C. , Premkumar N. , Jeong Yeon Tae
Published: September 2012

Most of the compounds with chloro‐substitution at the C‐6 or C‐7 position show potent antibacterial and antifungal as well as analgesic and antiinflammatory activities.
ChemInform Abstract: Gold(I)‐Catalyzed Cycloisomerization of Nitrogen‐ and Oxygen‐Tethered Alkylidenecyclopropanes to Tricyclic Compounds.
Authors: Zhang Di‐Han , Wei Yin , Shi Min
Published: September 2012

The new, very mild, air‐ and moisture‐tolerant title reaction is presented.
ChemInform Abstract: A Solvent‐Free, Four‐Component Synthesis and 1,3‐Dipolar Cycloaddition of 4(H)‐Pyrans with Nitrile Oxides: Synthesis and Discovery of Antimycobacterial Activity of Enantiomerically Pure 1,2,4‐Oxadiazoles.
Authors: Almansour Abdulrahman I. , Kumar Raju Suresh , Arumugam Natarajan , Sriram Dharmarajan
Published: September 2012

Four‐component reaction between tetrahydropyridinone derivative (I), an aromatic aldehyde (II) and malononitrile (III) under solvent‐free conditions affords an inseparable mixture of two diastereomeric pyrans (IV) in near quantitative yield.
ChemInform Abstract: Synthesis of a Novel Series of 1,6‐Disubstituted‐3‐(cyclohexylmethoxy)‐β‐carboline Derivatives via Minisci Reaction.
Authors: Lin Guowu , Wang Yue , Zhou Qingfa , Wang Jian , Yang Taotao , Wang Zhanwei , Lu Tao
Published: September 2012

A simple and efficient synthetic route fallows the formation of title compounds (VII) (22 examples) via Minisci reaction as the key step [→ (VI)].
ChemInform Abstract: Acetic Anhydride Mediated Condensation of Aromatic o‐Diacid Dichlorides with Benzimidazoles to Provide Electroreducible p‐Dione Adducts.
Authors: Joyce Eamonn , Kavanagh Paul , Leech Donal , Karpinska Jolanta , McArdle Patrick , Aldabbagh Fawaz
Published: September 2012

It is demonstrated that acetic anhydride allows a very rapid condensation of o‐diacid dichlorides with imidazole and benzimidazoles.
ChemInform Abstract: Ring Closing and Opening Reactions Leading to Aza‐Polycyclic Aromatic Compounds.
Authors: Kethe Anila , Li Ang , Klumpp Douglas A.
Published: September 2012

The title compounds are obtained by a superacid‐promoted ring‐closing/ring‐opening cascade proceeding via a series of dicationic intermediates.
ChemInform Abstract: NH2SO3H and H6P2W18O62·18H2 O‐Catalyzed, Three‐Component, One‐Pot Synthesis of Benzo[c]acridine Derivatives.
Authors: Heravi Majid M. , Alinejhad Hamideh , Derikvand Fatemeh , Oskooie Hossein A. , Baghernejad Bita , Bamoharram Fatemeh F.
Published: September 2012

An efficient and practical three‐component, one‐pot preparation of polyhydroacridine derivatives proceeds under neat conditions in the presence of sulfamic acid or Wells—Dawson acid as catalyst.
ChemInform Abstract: Quinazolino—Benzothiazoles: Fused Pharmacophores as Anticonvulsant Agents.
Authors: Ugale Vinod G. , Patel Harun M. , Wadodkar Sudhir G. , Bari Sanjay B. , Shirkhedkar Atul A. , Surana Sanjay J.
Published: September 2012

A benzothiazole moiety is incorporated in the quinazoline nucleus by recyclization of benzoxazinone (I) with substituted aminobenzothiazoles (II).
ChemInform Abstract: Design, Synthesis and Antiviral Activity of Novel Quinazolinones.
Authors: Wang Qingmin , et al. et al.
Published: September 2012

Quinazolinone derivatives are designed and synthesized as novel anti‐HIV agents.
ChemInform Abstract: Acid Catalysis in the Oxidative Nucleophilic Alkoxylation of 1,3,7‐Triazapyrenes.
Authors: Borovlev I. V. , Demidov O. P. , Saigakova N. A.
Published: September 2012

The method leads to dialkoxylated products irrespective of the substrate ratio.
ChemInform Abstract: A Novel Intramolecular Ugi 3CC for the Synthesis of N‐Alkyl‐3‐oxo‐2‐aryl‐1,2,3,4‐tetrahydropyrazino [1,2‐a]indole‐1‐carboxamides.
Authors: Reddy B. V. Subba , Dey Sujit Kumar , Yadav J. S. , Sridhar B.
Published: September 2012

A novel intramolecular Ugi three‐component reaction of substrate (I) with amines and isonitriles is reported to provide the title compounds (IV).
ChemInform Abstract: Synthesis, Antitumor Activity and SAR Study of Novel [1,2,4]Triazino[4,5‐a]benzimidazole Derivatives.
Authors: El‐Nassan Hala Bakr
Published: September 2012

Title derivatives (III) are obtained upon cyclocondensation of benzimidazole derivative (I) with aryl and heteroaryl aldehydes (II).
ChemInform Abstract: Mannich‐Type Reaction for Synthesis of 3‐Methyl‐4‐nitroimino‐tetrahydro‐1,3,5‐oxadiazine.
Authors: Qu Wen‐Yan , She Dong‐Mei , Zhao Jian , Lin De‐Jie , Huang Qi‐Liang , Li Feng‐Min
Published: September 2012

Mannich reaction of N‐methyl‐N′‐nitroguanidine (I) in the presence of alkaline catalysts provides access to the title oxadiazine (III) and triazine derivative (IV).
ChemInform Abstract: Synthesis of a 1,3,5‐Benzotriazepine‐2,4‐dione Based Library.
Authors: Chuckowree Irina , Syed Murtaza Ali , Getti Giulia , Patel Asha Parbhu , Garner Hannah , Tizzard Graham J. , Coles Simon J. , Spencer John
Published: September 2012

In order to develop selective pyrathyroid hormone‐1‐receptor antagonists the cyclocondensation of functionalized o‐phenylenediamines (I) with phenyl isocyanatoformate is described to synthesize 1,3,5‐benzotriazepinediones.
ChemInform Abstract: A Concise Route to Indoloazocines via a Sequential Ugi—Gold‐Catalyzed Intramolecular Hydroarylation.
Authors: Modha Sachin G. , Vachhani Dipak D. , Jacobs Jeroen , Van Meervelt Luc , Van der Eycken Erik V.
Published: September 2012

The sequence affords the desired indoloazocines (VI).
ChemInform Abstract: A New Polycyclic System Containing the 1,4‐Benzodiazepine and Isoindolinone Fragments: Synthesis and Structure.
Authors: Ukhin L. Yu. , Suponitskii K. Yu. , Shepelenko E. N. , Belousova L. V. , Orlova Zh. I. , Borodkin G. S.
Published: September 2012

The formation of fused benzodiazepines (III) proceeds smoothly without any acid catalyst.
ChemInform Abstract: Microwave Accelerated Glaser—Hay Macrocyclizations at High Concentrations
Authors: Bedard Anne‐Catherine , Collings Shawn K.
Published: September 2012

8 examples
ChemInform Abstract: Synthesis of Functionalized Diarylborinic 8‐Oxyquinolates via Bimetallic Boron—Lithium Intermediates.
Authors: Wesela‐Bauman Grzegorz , Jastrzebski Lech , Kurach Pawel , Lulinski Sergiusz , Serwatowski Janusz , Wozniak Krzysztof
Published: September 2012

For the synthesis of the novel title compounds a simple one‐pot protocol, which uses readily available starting materials, is presented.
ChemInform Abstract: Alkylboronic Esters from Palladium‐ and Nickel‐Catalyzed Borylation of Primary and Secondary Alkyl Bromides.
Authors: Yi Jun , Liu Jin‐Hui , Liang Jun , Dai Jian‐Jun , Yang Chu‐Ting , Fu Yao , Liu Lei
Published: September 2012

Cross‐coupling reactions of primary alkyl bromides (I) with diboron reagent (II) give the desired organo‐boron compounds (III) in the presence of a palladium catalyst.
ChemInform Abstract: Synthesis of Functionalized 2,3,4,5‐Tetraphenylsilole Derivatives Through Hydrosilylation and Their Crystal Structures.
Authors: Zhang Yunsheng , Li Shuhong , Wang Rui , Chen Limin , Xu Caihong
Published: September 2012

Title compounds (III), prepared by hydrosilylation of p‐ethynylarenes (II), show aggregation‐induced emission effects.
ChemInform Abstract: Dialkyl (1‐Ethoxycarbonyl‐2,2,2‐trifluoro‐1‐phenylsulfonylaminoethyl) phosphonates.
Authors: Aksinenko A. Yu. , Sokolov V. B. , Goreva T. V. , Makhaeva G. F.
Published: September 2012

Novel fluorinated α‐amino phosphonates (III) are synthesized.