bluuebunny/crossref_metadata_2025 huggingface dataset:
FACTIBILIDAD ECONÓMICA Y AMBIENTAL DEL HORMIGÓN PREFABRICADO EN ESTRUCTURAS DE TECHOS DE VIVIENDAS EN CONJUNTOS HABITACIONALES
Authors: BRITEZ SILVERO Valentin , APARICIO María José
Published: November 2024

Con el objetivo de estudiar la factibilidad económica y ambiental del uso de Hormigón Prefabricado en estructuras de techos de viviendas en conjuntos habitacionales, en el departamento de Itapúa, Paraguay, se realizó la investigación, proponiendo este uso en sustitución a la tecnología tradicional de maderas nativas, como alternativas: económica y ambiental válidas para la construcción de viviendas encaradas por la EBY para la relocalización de los afectados por el embalse de la represa Hidroeléctrica YACYRETA y de conjuntos habitacionales ante el déficit habitacional en el país. El trabajo de investigación se enmarco dentro de una investigación descriptiva con una metodología cualitativa y se centra en el enfoque técnico de las alternativas tecnológicas. Se realizó un panel de expertos, como aplicación del método Delphi, con representantes de empresas constructoras, instituciones, fabricantes, proveedores de materiales y especialistas en la temática ambiental. Los resultados indican que a) el hormigón armado prefabricado cumple con los requisitos de resistencia y estabilidad estructural b) es factible económicamente c) el uso del hormigón armado tipo rigido, resuelve el problema de la falta de fabricantes en zona de obras en Itapúa. d) La aplicación de la tecnología propuesta mitigará este impacto. e) la adaptabilidad propia del pueblo Paraguayo ante el cambio facilita la aplicación de esta propuesta tecnológica.
DIAGNÓSTICO AMBIENTAL MUNICIPAL DE LA CIUDAD DE ENCARNACIÓN
Authors: VELÁZQUEZ HAURÓN Edith Jacqueline , PACHECO FIGUEREDO Viviana Marilyn , APARICIO Maria José
Published: November 2024

Se buscó elaborar un Diagnóstico Ambiental Municipal de la ciudad de Encarnación, considerando los criterios fijados en la Agenda 21. El estudio fue descriptivo-cualitativo con herramientas cuantitativas y se realizaron encuestas de sondeo público en 29 barrios del municipio y entrevistas a las autoridades municipales relacionadas con el medio ambiente. Los resultados indican que la ciudadanía considera como aspectos insatisfechos y a mejorar: transporte público 81%, seguridad ciudadana 52%, recogida de basuras 48%, entre otros. En su mayoría manifestó la necesidad de incrementar espacios verdes de uso público. debido al crecimiento urbanistico y alta predisposición para la clasificación de residuos. Los responsables de la mejora son: la Municipalidad (99%), el Gobierno Departamental (81%). los ciudadanos (59%), las comisiones vecinales (51%) y otros. Los consultados manifestaron conciencia ambiental, falta de participación ciudadana en proyectos comunales y predisposición a adoptar mejores prácticas ambientales apostando a la educación ambiental como prioridad del Municipio.
Síndrome metabólico en funcionarios del Hospital Regional de Encarnación
Authors: González Roberto , Madrazo Carolina , Knapke Federico , Ramos Carlos , Cornaló Eduardo
Published: November 2024

Introducción: El síndrome metabólico es un conjunto de factores de riesgos que pueden conducir a un síndrome coronario agudo, se considera como conductor de la epidemia de la enfermedad cardiovascular. El objetivo de este estudio es determinar la prevalencia del Síndrome Metabólico en funcionarios del Hospital Regional de Encarnación definidos según ATP III.
 
Método de estudio: observacional, de corte transversal, se estudiaron 100 funcionarios del HRE sin distinción de rango, de ambos géneros, en edades comprendidas entre 20 a 65 años.
 
Resultados: La mayor parte de la población fueron mujeres entre 20 a 30 años, 7 personas eran prediabéticas y 4 padecían DM tipo 2. La prevalencia de dislipidemia era mayor afectando a 22 pacientes, y la mitad de la población presentaba disminución del HDL; 28 personas presentaban hipertrigliceridemia, 22 prehipertensión, 4 hipertensión estadio y 4 hipertensión estadio II.La mayoría presentaban aumento de peso, entre ellas predominaba el sobrepeso comparados con la obesidad que se presentó en menor número.
En 20 varones la circunferencia abdominal fue a 102 cm y en 43 mujeres la CA fue a 88 cm.15 varones y 21 mujeres tenían síndrome metabólico.
Gestión Académica enfocada desde la Calidad, de la Facultad de Ciencias Económicas y Administrativas de la Universidad Nacional de Itapúa – Paraguay
Authors: Ferreira Altamirano Nilse Graciela
Published: November 2024

El trabajo de investigación aborda la Gestión Académica de la Facultad de Ciencias Económicas y Administrativas de la Universidad Nacional de Itapúa, Paraguay, desde el enfoque de calidad, describe su posicionamiento, respondiendo las interrogantes sobre el “hacer” y desde “el deber hacer” de la gestión, reconociendo los principios de calidad presentes en la gestión tanto académica como administrativa y los factores que influyen en el logro de la Calidad.
El nivel de la investigación es exploratorio-descriptivo, con enfoque fenomenológico y multimodal o mixto. El universo de estudio está compuesto por Directivos, Docentes, Alumnos, Egresados y Directivos de Empresas. Los instrumentos fueron aplicados al 42% de la población.
Los hallazgos permiten inferir que la institución, se caracteriza por contar con una estructura organizacional acorde a las necesidades, coherente en su funcionamiento interno, con evidencias de cumplimiento de sus propósitos, misión y objetivos. Los procedimientos administrativos y financieros son medianamente adecuados conforme a la asignación, ejecución y control que el presupuesto requiere para la implementación del Proyecto Educativo. Estos factores posicionan a la institución en gran medida con
respecto a los parámetros de calidad.
A partir de los resultados de la investigación, se propone un plan de mejora, en el cual se resalta la necesidad de potenciar la comunicación, capacitación, actualización, atención de los recursos humanos, revisión del presupuesto para cumplir con el plan de desarrollo, implementar los mecanismos de seguimiento, evaluación y desarrollo del grado de cumplimiento de los proyectos educativos y de los estándares de calidad, para asegurar la permanencia de la institución en el mercado y en el tiempo.
Planificación estratégica para la mejora de la calidad de vida de familias de la compañía santa rita distrito de coronel bogado
Authors: Vallejos de Cuella Rosa María , Galeano de Villalba Elsa De las Nieves , Noguera Iris Noemí
Published: November 2024

Teniendo en cuenta consideraciones constitucionales el presente trabajo Planificación Estratégica para la mejora de la calidad de vida de familias de la compañía Santa Rita Distrito de Coronel Bogado aborda aspectos emergentes y que requieren un tratamiento responsable en la Cía. localizado en el Departamento de Itapúa República del Paraguay.
Lo concreto que se observa y demostrado por la Aplicación de un Foda priorizado y el Método Sinfonía es que la mayoría de sus pobladores, tanto mayores y menores, carecen de las condiciones mínimas que aseguren su bienestar de vida. El Municipio carece de experiencias de elaboración y ejecución de planes estratégicos de desarrollo integrado que propongan acciones conjuntas y diversificadas para el mejoramiento de la calidad de vida de sectores carenciados.
La parte de la población no se autoabastece para el consumo equilibrado de alimento, la asistencia técnica - educativa parece ausente y por tanto su economía sustentable no esta asegurada.
Intervención judicial y asistencial en casos de abuso sexual infantil denunciados en la ciudad de Encarnación
Authors: Martínez Rosa Orfilia
Published: November 2024

Este artículo es una investigación concerniente al ABUSO SEXUAL INFANTIL (A.S.I.) denunciados en el año 2012 en la cuidad de Encarnación. Se intentó conocer los procedimientos del sistema judicial y asistencial en las instituciones intervinientes, como también las características principales de los casos denunciados de A.S.I. Metodológicamente se solventó mediante un estudio de tipo descriptivo/explicativo, teniendo como unidad de análisis a las víctimas de A.S.I., tomando como muestra 16 casos denunciados y principales referentes de instituciones intervinientes.
Educación para la Integración:
Authors: D'Angelo Guillermo Adrián
Published: November 2024

Esta Investigación Acción Participativa tuvo como objetivo general promover a través de la Universidad Nacional de Itapúa (UNI) la Educación para la Integración en la zona de frontera Encarnación Posadas, considerando que ambas ciudades forman parte de una matriz común. Se trata de una investigación cualitativa, la cual está sustentada bajo un paradigma socio-crítico. La misma contó con la colaboración de ocho alumnos monitores, quienes entrenados previamente en las nociones de IAP, procedieron a guiar a los distintos grupos focales constituidos por estudiantes de diversas Facultades la Universidad Nacional de Itapúa. Los instrumentos aplicados a los grupos focales a fin de determinar la realidad emergente fueron Diagramas de Ishikawa y una Guía de Discusión.
Una vez determinada tal realidad emergente, a través de la percepción de los integrantes de los grupos focales, se concluyó en la necesidad de diseñar e impulsar mediante la Universidad Nacional de Itapúa, un Programa de Educación para la Integración que coadyuve en la creación de competencias transfronterizas. El Programa de Educación para la Integración, diseñado en el contexto de la presente investigación, está conformado por objetivos y contenidos que se consideran pertinentes a la realidad emergente determinada a través de los distintos grupos focales.
Embarazo ectópico cervical tratado con metotrexate. Estudio de un caso. Hospital materno infantil reina Sofía
Authors: Ferreira Cyncar Fernando Rubén
Published: November 2024

Se presenta el caso de una paciente con embarazo ectópico cervical, a quien se le administró metotrexate por vía intramuscular como alternativa al tratamiento quirúrgico. La terapia medicamentosa consistió en la administración de metotrexate por vía intramuscular en días alternos, en un total de 3 dosis, así como el uso de ácido fólico por vía oral en los días en que no se administró metotrexate. Se controló de manera estricta a la paciente clínicamente, con métodos laboratoriales y ecográficos. Se confirmó la eliminación del embarazo con resultados anatomopatológicos obtenidos de un legrado evacuador.
Prototipo de bastón inteligente para invidentes
Authors: Lezcano Irala Johana Gisselle , Cabral Franco Mary Carolina
Published: November 2024

Generalmente para movilizarse una persona no vidente en lugares desconocidos se emplea el bastón blanco, sin embargo éste no detecta obstáculos que se encuentran de la cintura para arriba, por lo cual en este trabajo se ha propuesto desarrollar un prototipo que pueda realizar las tareas que el bastón tradicional no puede, mediante una tecnología que es capaz de detectar diferentes obstáculos que se encuentren fuera del rango del bastón tradicional y notificar al usuario por medio de vibraciones cuando el obstáculo este cerca a él. El objetivo de este trabajo fue diseñar un prototipo de bastón inteligente para invidentes a través de una investigación aplicada. Se diseñó el prototipo de bastón inteligente teniendo en cuenta las siguientes etapas: a). Sistema de detección de obstáculos a partir del sensor por ultrasonido HY- SRF05.b). Sistema de teledetección c). Sistema de comunicación por medio de los módulos Ublox NEO6m y GPRS shield SIM900. En cada etapa se realizaron pruebas por medio de códigos programados en la plataforma Arduino Uno con el fin de analizar y comprobar el funcionamiento y rango de trabajo de cada módulo. El total de pruebas realizadas fueron siete, consiguiendo los resultados óptimos en cada prueba, las cuales al integrarse obtuvo un equipo sofisticado, económicamente accesible, utilizando componentes de alta calidad tecnológica y aplicable para cualquier tipo de baston independiente del material del que esté compuesto.
Efectividad del Código Aduanero del Paraguay. Un comparativo con las normativas de los Códigos Comunitario Europeo, Mercosur y CAROU
Authors: Silva Sotelo Maximo Alberto
Published: November 2024

La presente investigación consistió en analizar el Código Aduanero del Paraguay, iniciando con la descripción del sistema, partiendo de la fuente constitucional y demás normas reglamentarias afines. Se realizó una breve descripción de los problemas que suscitan para su aplicación teniendo como las deficiencias en la ejecución de la norma por la institución llamada Dirección Nacional de Aduanas. Se evidenció varios inconvenientes que se suscitan dentro del procedimiento, para demostrarlo se recolectaron muestras significativas en todos los ámbitos, importador exportador funcionario aduanero, y despachante de aduanas, todas ellas personas vinculadas a la actividad aduanera en el Séptimo Departamento del Paraguay llamado Itapua. Se utilizó una encuesta con preguntas abiertas a fin de recolectar evidencias validas, luego de procesar los resultados se analizó si la regla aduanera es técnicamente valida para su aplicación, comparándolas con legislaciones internacionales como la normativa Aduanera Comunitaria utilizada en la Unión Europea, como as tambien el Codigo Aduanero del Mercosur Convenios entre otras reglas que rigen la materia y realizando una comparación detallada con el Codigo Aduanero de la República Oriental del Uruguay Como resultado se destaca la eficacia eficiencia y modernidad de la normativa paraguaya asimismo, se determina porque ellas no dar resultados y se propuse trabajar tanto por los contextos legales como institucionales para llegar a una eficiencia y cambiar las debilidades encontradas e igualmente mejorar y actuar sobre la misma en forma integral.
Prevalencia de Preeclampsia en el Hospital Regional de Encarnación - 2013
Authors: Ferreira Cyncar Fernando Rubén
Published: November 2024

La preeclampsia es una enfermedad de origen desconocido. El objetivo principal del trabajo fue determinar la prevalencia de preeclampsia en pacientes gestantes que acudieron al servicio de maternidad del Hospital Regional de Encarnación en el periodo comprendido entre enero a diciembre 2013. El diseño fue descriptivo de tipo observacional, transversal, retrospectivo con componente analitico y arrojó los siguientes resultados: la prevalencia fue baja, se destacaron la nuliperidad y la multiparidad, un elevado porcentaje de pacientes refirió haber padecido dicha patologia en embarazos anteriores y el control pranatal nulo e insuficiente se destacaron en estas pacientes.
Indberetning til Indenrigsministeriet om Undersøgelserne i Aarene 1876, 1877 og 1878
Authors: Johnstrup F. , Ravn N.F. , Rink H.
Published: November 2024

Not available
Geologiske Iagttagelser fra Vestkysten af Grønland (62°15' – 64°15' N.B)
Authors: Kornerup A.
Published: November 2024

No abstract available
Bemærkninger om de af Cand. Kornerup i 1878 samlede Planter på Vestkysten af Grønland af J. Lange, og om det organiske Liv paa en af Nunatakkerne af A. Kornerup
Authors: Lange J. , Kornerup A.
Published: November 2024

No abstract available
Astronomiske og meteorologiske Observationer iaggtagne paa Rejsen i Syd-Grønland 1878
Authors: Jensen J. A. D.
Published: November 2024

Not available
Résumé des Communications sur le Grønland. Première Partie.
Authors: Johnstrup F.
Published: November 2024

Not available
The Eskimo Language, its admirable Organisation as to the Construction and Flexion of Words.
Authors: Rink H.
Published: November 2024

Intet resumé.
Sur la végétation du Grønland.
Authors: Warming Eug.
Published: November 2024

Intet resumé.
Indberetning til Indenrigsministeriet om Undersøgelserne i Aarene 1878, 1879 og 1880 paa Vestkysten af Gønland
Authors: Johnstrup F. , Ravn N.F, , Rink H.
Published: November 2024

Not available
Rèsumè des Communications sur le Grønland. Deuxième Partie
Authors: Johnstrup F.
Published: November 2024

Not available
Om Forekomsten af Nikkeljern med Widmannstättenske Figurer i Basalten i Nord-Grønland.
Authors: Steenstrup K. J. V.
Published: November 2024

Intet resumé.
Et Par Bemærkninger til Prof. Heers Afhandling i dette Hefte
Authors: Steenstrup K. J. V.
Published: November 2024

Intet resumé.
Forslag til en fra Søsiden foretaget Undersøgelse af Grønlands Østkyst.
Authors: Normann C. O. E.
Published: November 2024

Intet resumé.
Undersøgelse af Olivinsten fra Siorarsuit ved Kangamiut i Grønland.
Authors: Rørdam K.
Published: November 2024

Intet resumé.
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest
Authors: Casey-Clyde Tim , Liu S John , Serrano Juan Antonio Camara , Teng Camilla , Jang Yoon-Gu , Vasudevan Harish N , Bush Jeffrey O , Raleigh David R
Published: November 2024

The histone methyltransferase Polycomb repressive complex 2 (PRC2) is required for specification of the neural crest, and mis-regulation of neural crest development can cause severe congenital malformations. PRC2 is necessary for neural crest induction, but the embryonic, cellular, and molecular consequences of PRC2 activity after neural crest induction are incompletely understood. Here we show that
Eed
, a core subunit of PRC2, is required for craniofacial osteoblast differentiation and mesenchymal proliferation after induction of the neural crest. Integrating mouse genetics with single-cell RNA sequencing, our results reveal that conditional knockout of
Eed
after neural crest cell induction causes severe craniofacial hypoplasia, impaired craniofacial osteogenesis, and attenuated craniofacial mesenchymal cell proliferation that is first evident in post-migratory neural crest cell populations. We show that
Eed
drives mesenchymal differentiation and proliferation
in vivo
and in primary craniofacial cell cultures by regulating diverse transcription factor programs that are required for specification of post-migratory neural crest cells. These data enhance understanding of epigenetic mechanisms that underlie craniofacial development, and shed light on the embryonic, cellular, and molecular drivers of rare congenital syndromes in humans.
Cloud-based configurable data stream processing architecture in rural economic development
Authors: Chen Haohao , Al-Turjman Fadi
Published: November 2024

Purpose

This study aims to address the limitations of traditional data processing methods in predicting agricultural product prices, which is essential for advancing rural informatization to enhance agricultural efficiency and support rural economic growth.

Methodology

The RL-CNN-GRU framework combines reinforcement learning (RL), convolutional neural network (CNN), and gated recurrent unit (GRU) to improve agricultural price predictions using multidimensional time series data, including historical prices, weather, soil conditions, and other influencing factors. Initially, the model employs a 1D-CNN for feature extraction, followed by GRUs to capture temporal patterns in the data. Reinforcement learning further optimizes the model, enhancing the analysis and accuracy of multidimensional data inputs for more reliable price predictions.

Results

Testing on public and proprietary datasets shows that the RL-CNN-GRU framework significantly outperforms traditional models in predicting prices, with lower mean squared error (MSE) and mean absolute error (MAE) metrics.

Conclusion

The RL-CNN-GRU framework contributes to rural informatization by offering a more accurate prediction tool, thereby supporting improved decision-making in agricultural processes and fostering rural economic development.
Exploring quadriceps activity variations in women: the role of seated posture during stair climbing
Authors: Chun SaBin , Park JongChul
Published: November 2024

Background

Adults in modern society spend most of their time in a sitting position. However, sitting for long periods of time can affect the length and sensation of the quadriceps muscle and negatively affect the performance of functional tasks required in daily life. In addition, it may have different characteristics according to sitting postures.

Aim

The aim of this study is to investigate the differences in quadriceps muscle activity during stair climbing and descending based on various sitting postures.

Methods

Thirty healthy adult women were classified into sitting upright (SU), sitting with legs crossed (SLC), and sitting with ankles crossed over knees (SAC). The muscle activities of the vastus medialis (VM), vastus lateral (VL), and rectus femoris (RF) were collected during climbing and descending the stairs three times each. After which a sitting posture was maintained for 15 min, the post-measurement was performed in the same way as the pre-measurement. One-way analysis of variance or Kruskal-Walli’s test was used to check homogeneity between each group, least significant difference (LSD) was used for post-hoc testing. Paired-sample t-test or Wilcoxon signed-rank test was used to check before-and-after differences within the group. Repeated measures analysis of variance was used to determine between-group and within-group interactions.

Results

VM muscles were significantly decreased after maintaining a sitting posture during descending stairs of SAC group (p = 0.047). In conclusion, this study indicates that maintaining a SAC sitting posture for a certain period causes a temporary decrease in muscle activity of the VM muscle during descending stairs. This provides important implications for early treatment to manage knee pain and strengthen quadriceps muscles in women. Future studies should focus on groups with patellofemoral pain syndrome or knee pain to better understand the impact of sitting posture on quadriceps activity.
Os desafios enfrentados na implementação e prática da telemedicina
Authors: Kogien Adriano Braga , Barroso Camyla Coutinho , Assayag Dinah Elisa Silva , Freitas Eduarda Caroline Lopes de , Costa Lohana Frota Nogueira , Pontes Marcella Kamilla Vargas da Cunha , Roberto José Carlos Alves , Lima Suelen Costa
Published: November 2024

A telemedicina já é uma realidade no Brasil, sendo potencializada pelos reveses da pandemia da COVID-19, mas sua prática ainda apresenta desafios que carecem de solução em prol do atendimento aos pacientes com qualidade e segurança. O objetivo geral do estudo consistiu em analisar os desafios encontrados nos atendimentos realizados por telemedicina na perspectiva brasileira e os meios para sua resolução. O método utilizado foi uma revisão bibliográfica, com lapso temporal entre 2019 e 2024, por meio de consultas em bases de dados como Medline, SciELO e a Biblioteca Virtual de Saúde. Deste processo de busca, foi possível identificar 8 produções que se mostraram condizentes com os propósitos da pesquisa. Os resultados apontam que os desafios englobam desde a dimensão cultural, abarcando a resistência de médicos e pacientes com relação a telemedicina, bem como dificuldades de ordem técnica, representadas pelo estado precário de internet. Soma-se a isso a questão ética e regulatória, numa dimensão em que haja a segurança jurídica para os médicos atuantes na telemedicina. O estudo conclui que, mesmo com os benefícios que a telemedicina apresenta, situações como a educação continuada em saúde e infraestrutura tecnológica adequada para a realização dos atendimentos são essenciais para que as pessoas tenham acesso à saúde de maneira adequada e apoiada pelas tecnologias da informação e comunicação.
Trend Analysis of Climate Change across Nigeria: A Mann-Kendall and Sen’s Approach
Authors: Iyeme E. E. , Ekah U. J. , Njok A. O. , Agbo E. P. , Offorson G. C.
Published: November 2024

This study investigates the long-term variations in temperature and precipitation across Nigeria’s climatic zones, focusing on their impact on agriculture and water resources. Using data from Calabar, Ibadan, Kano, and Kukawa to represent the tropical monsoon, tropical savannah, semi-arid and desert climate, respectively, the research adopts the Mann-Kendall trend test, innovative trend analysis, and anomaly analysis to assess climate trends and their implications. The findings reveal significant warming trends across all locations, particularly in semi-arid and desert zones like Kano and Kukawa, with temperature increase of 0.0443°C/year and 0.0412°C/year, respectively. It was further observed that precipitation trends varied by region, with Calabar showing a monthly decrease of -1.26 mm/year, while Kukawa exhibited an unexpected significant increase, which suggest potential greening in the desert. The study underscores the need for region-specific climate adaptation strategies. For instance, increased warming in semi-arid zones calls for enhanced water conservation efforts, while the rising precipitation in desert regions raises concerns about flood risks and water management. The results highlight the importance of multi-scale and spatial analysis to better inform climate-related policy decisions. National and regional policymakers must adopt targeted agricultural practices, improve water resource management, and implement climate resilience strategies to mitigate the adverse effects of these climatic shifts.
Formulation and Evaluation of Paracetamol Tablet Using Konjac Glucomannan as Natural Halal Binder
Authors: Kumereshwaran Daneesha Deivy , Rahman Shamima Abdul
Published: November 2024

Introduction: Discovery and development of novel halal excipients in tablet formulation have led to continuous interest in drug delivery research. In this study, Konjac Glucomannan, a polysaccharide derived from the tuber of Amorphophallus konjac, was used as a halal binder in the formulation of paracetamol tablets.
Objective: This study aims to formulate and evaluate paracetamol tablets using konjac glucomannan as a halal binder.
Methodology: Paracetamol tablets were formulated with different concentrations (5%, 10%, 15%, 20%) of KGM using the wet granulation method. The formulated paracetamol granules and tablets were subjected to different quality control tests.
Results: All four formulation granules passed the pre-compression test, indicating good to passable powder flowability. The weight variation, hardness, thickness, and disintegration test results for all four formulations were within the USP limit except for the friability test. Only tablets with 20% KGM passed the test.
Conclusion: 20% KGM shows good tablet binding properties compared to 5%, 10%, and 15% KGM. Hence, paracetamol tablets formulated with higher KGM as a binder produce paracetamol tablets with good physical and mechanical properties.
Genetic Characterisation and Molecular Phylogeny of Mosquito Aedes vittatus Based on COI Gene from Bhawanipatna, Kalahandi, Odisha, India
Authors: Panigrahi Subrat Kumar , Parida Smruti Ranjan , Das Jitendra , KumarBehera Raj , Nayak Nihar Ranjan
Published: November 2024

Introduction: Aedes vittatus is common throughout India and breeds in a variety of locations, including tree holes, cement tanks, rock pools, abandoned containers close to residential areas, and marsh pools. The invasive mosquito species Aedes vittatus has expanded its range across Africa, Asia, Latin America, and Europe. Mosquito species have been successfully identified by characterising a portion of the cytochrome c oxidase subunit 1 (cox1) gene, particularly in light of the difficulty in differentiating mosquito larvae and the scarcity of qualified taxonomists.
Objective: The current study was designed for molecular characterisation of the Aedes vittatus mosquitoes collected from all parts of Bhawanipatna based on mitochondrial COI to provide a wider understanding of the phylogenetic relationships of Aedes vittatus mosquitoes that exist throughout India. The genetic relatedness between Indian mosquitoes and those reported from other parts of the world was also investigated.
Material and Methods: The collection of data was made from different locations of Bhawanipatna Municipal Corporation, the headquarter of the district of Kalahandi, Bhawanipatna is located at 19.9°N 83.17°E. Adult Aedes mosquitoes were surveyed weekly from the selected human dwelling, both inside and outside the house or premises of Bhawanipatna Municipal area from month June 2024 to October 2024. Adult mosquitoes were collected with the help of a manual aspirator tube and a torch light. DNA was isolated from the provided culture. Quality was evaluated on 1.8% Agarose Gel; a single band of high-molecular weight DNA has been observed. The consensus sequence was generated for each sample using BioEdit version 6.0.7 and were searched over the GenBank database using Basic Local Alignment Search Tool (BLAST) against the Aedes vittatus genomes in NCBI, GenBank. The complete sequences were deposited in GenBank with accession no. PQ477920.1.
Conclusion: Aedes vittatus vector might be introduced to Kalahandi, Odisha from neighbouring states. The presence of this competent vector is most probably a risk of transmission of arboviruses such as Dengue fever, Yellow fever, West Nile virus, Zika virus and Chikungunya virus in this area.
Evaluation of Different Microbial Consortia for Decomposing Different Wastes: An In vitro and In vivo Study Approach
Authors: Mali Rajashri Harishchandra , Ghante P. H. , Magar S. J. , Patil Neha Hemant , Kuthumbare R. S.
Published: November 2024

If not managed properly, agricultural solid waste can cause environmental and health problems, including pollution and respiratory issues. Recycling these wastes through composting is a viable method to enhance soil health, reduce environmental impact and mitigate climate change. The results demonstrated that microbial consortia, particularly the T7 consortium (T. h. + T. k + P. c+ A. f. + A. n.+ B. s. + P. f), significantly accelerated the composting process, reducing decomposition time and improving compost maturity compared to single microbial cultures and un-inoculated controls. Efficient composting helps in waste management and improves soil quality and sustainable Agriculture. Key observations over a 105-day composting period included changes in texture, total days required, moisture content and pH. Microbial treatments also led to favorable changes in moisture retention, pH stabilization towards neutral or slightly alkaline conditions, and enhanced nutrient content, particularly with Trichoderma harzianum and Pseudomonas fluoroescens. The study reveals that the use of efficient microbial consortia can substantially enhance the composting of agricultural residues, contributing to effective waste management and sustainable agricultural practices.
Advancements In UAV Wing Design: Aerodynamic Performance, Structural Integrity And Optimization Techniques
Authors: Ahmed Abdul Mateen Manzoor , Krishna B. Vamshi , Manoj D.
Published: November 2024

The aerodynamic performance and optimization of unmanned aerial vehicles (UAVs) have garnered significant
research interest, driven by the need for enhanced efficiency, stability, and adaptability in various flight
conditions. This paper reviews current research on UAV wing configurations, focusing on aerodynamic
optimization, structural integrity, and computational fluid dynamics (CFD) analysis. Studies on innovative wing
designs, such as blended-wing-body and fixed-wing configurations, demonstrate improvements in lift, drag, and
maneuverability through precise airfoil selection and wing parameter optimization. Structural optimization,
particularly the strength-to-weight ratio, is highlighted as essential for balancing aerodynamic performance
with structural robustness. CFD analysis has proven valuable in evaluating the effects of wingtip devices and
varying aerodynamic loads, enabling detailed assessments of airflow behavior, pressure distribution, and vortex
formation. This review identifies key trends and gaps in the literature, emphasizing the potential of advanced simulation and optimization techniques to further enhance UAV performance, efficiency, and mission-specific adaptability
A Review Of Effective Energy Utilization And Optimization In Hospital Buildings – Environmental And Economic Benefits
Authors: Saka Quadri , Oyedepo Sunday , Olanipekun Adewoye , Omotoso Hakeem
Published: November 2024

Background: Energy is important to modern life, because it is a critical driver for socio-economic development,
especially in developing countries like Nigeria. However, it comes at a price to consumers and at an even
greater price to the environment, because of environmental pollution caused by fossil fuels used for energy
generation. Therefore, this study assessed energy consumption in Nigerian hospital buildings to determine
economic and environmental benefits derivable from its effective utilization.
Materials and Methods: A systematic review of literature published between 2016 and 2024 on the Scopus and
Google scholar platforms was conducted to evaluate the current level of energy audits in Nigerian buildings,
present condition of energy conservation programmes and techniques used to optimize energy consumption in
Nigerian hospitals.
Results: Results revealed there are very few studies about energy audits in Nigerian buildings and they are
poorly reported. Majority of the challenges preventing energy conservation in Nigerian buildings are low
energy literacy, financial constraints, wasteful consumption attitudes, poor consumer-utility relationships and
use of outdated technologies. Adopting solar photovoltaic systems, energy management systems and retrofitting
existing hospitals will yield significant energy savings. Energy utilization is beneficial to the environment
because it significantly reduces carbon gas emissions into the atmosphere, by providing alternative clean,
sustainable and eco-friendly renewable energy sources. Effective energy utilization in hospital buildings
reduces average annual consumption by 20% while saving about 500 megawatts per hour.
Conclusion: This study concludes that regular hospital energy audits will reveal areas where energy is being
wasted and the techniques required for optimizing consumption in the areas. This study recommends using modern technologies for energy audits and educating hospital staff about energy conservation and optimization
A Practical Guide to Prepare and Synthetically Modify Graphene Quantum Dots
Authors: Sweetman Martin J. , Hickey Shane M. , Brooks Doug A. , Hayball John D. , Plush Sally E.
Published: February 2019

Due to the favorable properties of graphene quantum dots (GQDs), there has been a rapid development of sensors, devices, and composite materials, which incorporate this 0D nanomaterial. GQDs provide a means to instill superior optical, electronic, mechanical, and adsorptive properties to various platforms and have found use as biosensors, photovoltaic devices, polymer composites, and drug delivery vehicles. One of the key factors to successfully integrating GQD technology is the intelligent choice of synthetic chemical pathways to fabricate, modify, and instill functionality in the developed platform. GQDs are decorated with a variety of functional groups that are amenable to traditional synthetic chemistry transformations; however, the technology for post‐synthetic modifications is only in its infancy. Herein, a comprehensive analysis of the chemistry available for modifying GQDs is provided; starting from methods for GQD fabrication and synthetic chemical pathways for producing functional GQDs, to the advantages, disadvantages, and challenges of specific chemistries, and finally techniques for the appropriate characterization of these functional materials. This review is meant for researchers considering entering the GQD field, as well as those more experienced, providing a practical guide on how to prepare, modify, and characterize GQDs for a broad range of applications.
A 0D Lead‐Free Hybrid Crystal with Ultralow Thermal Conductivity
Authors: Haque Md Azimul , Gandi Appala Naidu , Mohanraman Rajeshkumar , Weng Yakui , Davaasuren Bambar , Emwas Abdul‐Hamid , Combe Craig , Baran Derya , Rothenberger Alexander , Schwingenschlögl Udo , Alshareef Husam N. , Dong Shuai , Wu Tom
Published: February 2019

Organic–inorganic hybrid materials are of significant interest owing to their diverse applications ranging from photovoltaics and electronics to catalysis. Control over the organic and inorganic components offers flexibility through tuning their chemical and physical properties. Herein, it is reported that a new organic–inorganic hybrid, [Mn(C2H6OS)6]I4, with linear tetraiodide anions exhibit an ultralow thermal conductivity of 0.15 ± 0.01 W m−1 K−1 at room temperature, which is among the lowest values reported for organic–inorganic hybrid materials. Interestingly, the hybrid compound has a unique 0D structure, which extends into 3D supramolecular frameworks through nonclassical hydrogen bonding. Phonon band structure calculations reveal that low group velocities and localization of vibrational energy underlie the observed ultralow thermal conductivity, which could serve as a general principle to design novel thermal management materials.
Multicore–Shell Bi@N‐doped Carbon Nanospheres for High Power Density and Long Cycle Life Sodium‐ and Potassium‐Ion Anodes
Authors: Yang Hai , Xu Rui , Yao Yu , Ye Shufen , Zhou Xuefeng , Yu Yan
Published: February 2019

Bismuth (Bi) is an attractive material as anodes for both sodium‐ion batteries (NIBs) and potassium‐ion batteries (KIBs), because it has a high theoretical gravimetric capacity (386 mAh g−1) and high volumetric capacity (3800 mAh L−1). The main challenges associated with Bi anodes are structural degradation and instability of the solid electrolyte interphase (SEI) resulting from the huge volume change during charge/discharge. Here, a multicore–shell structured Bi@N‐doped carbon (Bi@N‐C) anode is designed that addresses these issues. The nanosized Bi spheres are encapsulated by a conductive porous N‐doped carbon shell that not only prevents the volume expansion during charge/discharge but also constructs a stable SEI during cycling. The Bi@N‐C exhibits unprecedented rate capability and long cycle life for both NIBs (235 mAh g−1 after 2000 cycles at 10 A g−1) and KIBs (152 mAh g−1 at 100 A g−1). The kinetic analysis reveals the outstanding electrochemical performance can be attributed to significant pseudocapacitance behavior upon cycling.
Water Transfer Printing Enhanced by Water‐Induced Pattern Expansion: Toward Large‐Area 3D Electronics
Authors: Le Borgne Brice , Liu Siyi , Morvan Xavier , Crand Samuel , Sporea Radu Alexandru , Lu Nanshu , Harnois Maxime
Published: February 2019

Perfectly wrapping planar electronics to complex 3D surfaces represents a major challenge in the manufacture of conformable electronics. Intuitively, thinner electronics are easier to conform to curved surfaces but they usually require a supporting substrate for handling. The water transfer printing (WTP) technology utilizes water surface tension to keep ultrathin electronics floating flat without supporting substrate, enabling their conformal transfer on 3D surfaces through a dipping process. In many cases, however, the size of the microfabricated electronics is much smaller than the target 3D surface. This work proposes that such mismatch in size can be overcome by leveraging stretchable electronics in WTP. Stretchable electronics are compliant to in‐plane stretch induced by water surface tension, hence can first self‐expand in water and then be transferred onto 3D objects. Uniaxial and biaxial expansion ranging from 41% to 166% has been achieved without any externally applied tension. The results demonstrate that expansion‐enhanced WTP is a promising fabrication process for conformable electronics on large 3D surfaces.
A Multiparameter Pressure–Temperature–Humidity Sensor Based on Mixed Ionic–Electronic Cellulose Aerogels
Authors: Han Shaobo , Alvi Naveed Ul Hassan , Granlöf Lars , Granberg Hjalmar , Berggren Magnus , Fabiano Simone , Crispin Xavier
Published: February 2019

Pressure (P), temperature (T), and humidity (H) are physical key parameters of great relevance for various applications such as in distributed diagnostics, robotics, electronic skins, functional clothing, and many other Internet‐of‐Things (IoT) solutions. Previous studies on monitoring and recording these three parameters have focused on the integration of three individual single‐parameter sensors into an electronic circuit, also comprising dedicated sense amplifiers, signal processing, and communication interfaces. To limit complexity in, e.g., multifunctional IoT systems, and thus reducing the manufacturing costs of such sensing/communication outposts, it is desirable to achieve one single‐sensor device that simultaneously or consecutively measures P–T–H without cross‐talks in the sensing functionality. Herein, a novel organic mixed ion–electron conducting aerogel is reported, which can sense P–T–H with minimal cross‐talk between the measured parameters. The exclusive read‐out of the three individual parameters is performed electronically in one single device configuration and is enabled by the use of a novel strategy that combines electronic and ionic Seebeck effect along with mixed ion–electron conduction in an elastic aerogel. The findings promise for multipurpose IoT technology with reduced complexity and production costs, features that are highly anticipated in distributed diagnostics, monitoring, safety, and security applications.
Magnetically Hollow Pt Nanocages with Ultrathin Walls as a Highly Integrated Nanoreactor for Catalytic Transfer Hydrogenation Reaction
Authors: Ai Yongjian , Hu Zenan , Liu Lei , Zhou Junjie , Long Yang , Li Jifan , Ding Mingyu , Sun Hong‐Bin , Liang Qionglin
Published: February 2019

Fabricating efficient and stable nanocatalysts for chemoselective hydrogenation of nitroaromatics is highly desirable because the amines hold tremendous promise for the synthesis of nitrogen containing chemicals. Here, a highly reactive and stable porous carbon nitride encapsulated magnetically hollow platinum nanocage is developed with subnanometer thick walls (Fe3O4@snPt@PCN) for this transformation. This well‐controlled nanoreactor is prepared via the following procedures: the preparation of core template, the deposition of platinum nanocage with subnanometer thick walls, oxidative etching, and calcination. This highly integrated catalyst demonstrates excellent performance for the catalytic transfer hydrogenation of various nitroaromatics and the reaction can reach >99% conversion and >99% selectivity. With the ultrathin wall structure, the atom utilization of platinum atoms is highly efficient. The X‐ray photoelectron spectroscopy results indicate that partial electrons transfer from the iron oxides to Pt nanowalls, and this increases the electron density of snPt nanoparticles, thus promoting the catalytic activity for the transfer hydrogenation of nitroaromatics. For the reduction of 4‐nitrophenol, the reaction rate constant K
app is 0.23 min−1 and the turnover frequency (TOF) is up to 3062 h−1. Additional reaction results illustrate that this magnetic nanoreactor can be reused more than eight times and it is a promising catalytic nanoplatform in heterogeneous catalysis.
Chimeric antigen receptor T cell immunotherapy for multiple myeloma: A review of current data and potential clinical applications
Authors: Susanibar Adaniya Sandra P. , Cohen Adam D. , Garfall Alfred L.
Published: February 2019

Multiple myeloma (MM) is a malignant plasma cell disorder that remains incurable for most patients despite significant improvements achieved with modern therapy. Tumor evasion is a key process in the pathogenesis of MM and a compromised immune system is associated with more aggressive forms of the disease. In contrast, the emergence of myeloma‐specific immune responses after both autologous and allogeneic stem cell transplantation is associated with better prognosis. Adoptive T cell therapies may improve specific anti‐myeloma immunity resulting in long‐lasting remissions. CAR T cell therapies for MM are at an early stage of clinical development. To date, anti‐BCMA CAR T cells have shown the greatest results in early‐phase clinical trials. Toxicities have included cytokine release syndrome (CRS) and neurotoxicity. Current areas of research in CAR T cell therapies include the use of gene‐editing to enhance their effectiveness and safety, the integration of CAR T cells with other therapies (immunomodulatory drugs, checkpoint inhibitors) and CAR T cells to target multiple antigens.
Co‐shared genetics and possible risk gene pathway partially explain the comorbidity of schizophrenia, major depressive disorder, type 2 diabetes, and metabolic syndrome
Authors: Postolache Teodor T. , del Bosque‐Plata Laura , Jabbour Serge , Vergare Michael , Wu Rongling , Gragnoli Claudia
Published: February 2019

Schizophrenia (SCZ) and major depressive disorder (MDD) in treatment‐naive patients are associated with increased risk for type 2 diabetes (T2D) and metabolic syndrome (MetS). SCZ, MDD, T2D, and MetS are often comorbid and their comorbidity increases cardiovascular risk: Some risk genes are likely co‐shared by them. For instance, transcription factor 7‐like 2 (TCF7L2) and proteasome 26S subunit, non‐ATPase 9 (PSMD9) are two genes independently reported as contributing to T2D and SCZ, and PSMD9 to MDD as well. However, there are scarce data on the shared genetic risk among SCZ, MDD, T2D, and/or MetS. Here, we briefly describe T2D, MetS, SCZ, and MDD and their genetic architecture. Next, we report separately about the comorbidity of SCZ and MDD with T2D and MetS, and their respective genetic overlap. We propose a novel hypothesis that genes of the prolactin (PRL)‐pathway may be implicated in the comorbidity of these disorders. The inherited predisposition of patients with SCZ and MDD to psychoneuroendocrine dysfunction may confer increased risk of T2D and MetS. We illustrate a strategy to identify risk variants in each disorder and in their comorbid psychoneuroendocrine and mental–metabolic dysfunctions, advocating for studies of genetically homogeneous and phenotype‐rich families. The results will guide future studies of the shared predisposition and molecular genetics of new homogeneous endophenotypes of SCZ, MDD, and metabolic impairment.
Metal‐Free Regioselective Oxynitration of Acrylamides: Synthesis of 1,2‐Nitro Alcohols
Authors: Gao Le‐Han , Meng Xiao‐Xiao , Wang Yi‐Ning , Song Si‐Zhe , Ge Guo‐Ping , Dong Youren , Wei Wen‐Ting , Liu Yan‐Yun , Li Qiang
Published: February 2019

A metal‐free oxynitration of acrylamides with commercially available tert‐butyl nitrite and easily available air was achieved through a regioselective pathway. A wide range of 1,2‐nitro alcohols were thus eﬃciently synthesized in a novel route under mild conditions. The reaction involves a radical process, allows a highly regioselective strategy toward the formation of new C−N and C−O bonds in one step.
Catalytic, Enantioselective α‐Alkylation of Azlactones with Nonconjugated Alkenes by Directed Nucleopalladation
Authors: Nimmagadda Sri Krishna , Liu Mingyu , Karunananda Malkanthi K. , Gao De‐Wei , Apolinar Omar , Chen Jason S. , Liu Peng , Engle Keary M.
Published: February 2019

A palladium(II)‐catalyzed enantioselective α‐alkylation of azlactones with nonconjugated alkenes is described. The reaction employs a chiral BINOL‐derived phosphoric acid as the source of stereoinduction, and a cleavable bidentate directing group appended to the alkene to control the regioselectivity and stabilize the nucleopalladated alkylpalladium(II) intermediate in the catalytic cycle. A wide range of azlactones were found to be compatible under the optimal reaction conditions to afford products bearing α,α‐disubstituted α‐amino‐acid derivatives with high yields and high enantioselectivity.