bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on Oviposition and Hatching Period in Rhipicephalus(Boophilus) Microplus (Acari: Ixodidae) under Laboratory Conditions
Authors: Singh Ritika , Bagherwal R K , Jayraw A K , Choudhary Nidhi S , Kavani Md Akil S
Published: March 2020

Ticks are highly specialized distributed worldwide obligatehematophagous ectoparasites of mammals, birds, and reptiles. Amongst the species of ticks infecting cattle in India, Rhipicephalus microplus is the most widely distributed tick and established as the principal vectors of pathogens like Babesia and Anaplasma species (Ghosh and Nagar, 2014). Changes in the ovipositional and hatching pattern of these parasites are observed depending on the atmospheric conditions. Severalextrinsic factors Such as rainfall, temperature, humidity,floods, winds and physical damage affect the successful reproductive performance and survival of ixodid ticks after detachment from their hosts (Dipeolu, 1984). This study was aimed to evaluate the period of oviposition and hatching of eggs in engorged female ticks R.(B.) microplus collected from cattle in and around Indore.
Cuticular and Medullary Structure of Some Wild Herbivoresof India
Authors: Charjan Rupali , Nandeshwar N C , Banubakode S B , Kurkure N V , Bonde S W
Published: March 2020

The dorsal guard hair is considered as a mammalian exoskeleton. The anatomical feature of the three concentric layers of the mammalian hair, viz., medulla, cortex, and cuticle vary considerably with different species. The characteristics features of cuticular scales and medullary pattern can be used as an important tool for species identification by using various methods for hair analysis. The morphological features of cuticle and medulla of dorsal guard hair samples of Sambar (Rusa unicolor), Nilgai/blue bull (Boselaphus tragocamelus) and Spotted deer (Axix axis), six each, were studied during post-mortem examination. The microscopic studies showed a difference in some of the cuticular scale and medullar cells among three species. Hence, a single morphological feature of hair may not be a confirmative tool for species identification but multiple morphological features can be used as a confirmative tool of species identification. This study provides pictographic details in eead of some wild species which can be used to curb criminal acts against wild animals.
Seasonal Influence on Sexual Behaviour of Jaffrabadi Buffalo Bulls
Authors: Parmar K H , Dhami A J , Kavani F S , Solanki G B , Murthy K  S
Published: March 2020

The study was carried out on four mature Jaffrabadi breeding bulls (4–6 years old) maintained at Cattle Breeding Farm, JAU, Junagadh
for a period of 8 months during winter and summer. The seasonal and bull variations in sexual behavior traits were studied. A total of 64
observations (32 per season, 8 per bull) were availed at the fortnightly interval. The mean values/ scores for temperament (0–5 scale),
libido (0–9 scale), penile erection (0–4 scale), protrusion (0–4 scale), intensity of thrust (0–4 scale), reaction time (sec) and Flehmen
reaction (0, 1) during winter season were 1.28 ± 0.08, 6.75 ± 0.19, 3.22 ± 0.74, 2.88 ± 0.59, 3.15 ± 0.65, 125.00 ± 6.92 and 0.91 ± 0.43,
respectively, while the respective values in summer season were 2.22 ± 0.07, 5.93 ± 0.43, 2.84 ± 0.65, 2.75 ± 0.59, 2.93 ± 0.13, 143.5 ±
7.07 and 0.88 ± 0.06. There were significant differences among seasons for temperament, libido and penile erection score of Jaffrabadi
bulls. Significant differences among bulls were also found for libido score, the intensity of thrust and reaction time in the winter season,
and for ejaculatory thrust in the summer season. All these traits were highly significantly and positively interrelated (r = 0.353 to 0.512),
except Flehmen reaction and reaction time which were negatively correlated with all other behavioral traits (r = –340 to –0.499). Summer
in general significantly exerted an adverse effect on the sexual behavior of Jaffrabadi bulls, and winter was the favored season. It could
be concluded from the study that the Jaffrabadi bulls had good sexual behavior scores throughout both the seasons, however, bulls
showed better sexual behavior during winter as compared to summer.
Effect of Herbal Extracts of Bryophyllum calycinum and Achyranthes aspera on Serum Biochemical Profile of Rats having Adenine Induced Chronic Kidney Disease
Authors: Gehani Mukesh T , Raval S K , Panchal M T , Rao Neha
Published: March 2020

The experiment was undertaken to study the therapeutic efficacy of aqueous and alcoholic extracts of Bryophyllum calycinum and Achyranthes aspera on adenine induced chronic kidney disease (CKD) in male Wistar rats. The rats (n = 48) were divided randomly into eight equal groups (n = 6 each). Group I and II served as normal and adenine control, respectively. In group II to VIII, CKD was induced by administration of adenine (200 mg/kg) along with drinking water for 28 days. After 28th day, the rats of CKD induced Groups III to VIII were given aqueous and alcoholic plant extracts of B. calycinum and A. aspera @ 300 mg/kg b.wt. orally as either single or combination of both herbal extracts (3:1) in 0.5 % sodium bicarbonate using syringe and rat gavage needle. CKD was confirmed by evaluating serum biochemical parameters before and after herbal treatment. Increased levels of serum glutamic pyruvic transaminase, urea nitrogen, uric acid, creatinine and phosphorus, while decreased levels of serum total protein were observed in all CKD groups by 28th day as compared to 0 day or normal control group, which was significantly reverted to near normal levels by day 70th following administration of single aqueous/alcoholic extract or a combination as biherbal extracts (3:1) from day 28 to 70 of experiment. The serum albumin and calcium, however, did not show significant alteration in any of the groups. Results of serum biochemistry revealed that aqueous and alcoholic extracts of B. calycinum and A. aspera possess good therapeutic/nephroprotective efficacy against CKD. The effect of biherbal alcoholic extract of the plants was much better in restoring the biochemical values of CKD induced rats by 42 days of administration.
Pattern of Follicular Development, CL Size, Steroid Hormones and Biochemical Profile during Early Pregnancy in Heifers and Cows
Authors: Hadiyal K K , Dhami A J , Lunagariya P M , Sarvaiya N P
Published: March 2020

The follicular development, CL size, plasma progesterone (P4), estradiol-17β (E2), total cholesterol and blood glucose profiles were studied in 6 post-pubertal cyclic heifers and 6 postpartum cyclic cows each of Gir and HF x Kankrej breeds at weekly interval from day 0 (estrus/AI) to day 21 post-AI and then on days 23, 28, 35 and 42 in non-return cases. The mean CL size in heifers (irrespective of breeds) as monitored by transrectal ultrasonography on days 0, 7, 14, 21, 23, 28, 35 and 42 post-AI was found to be 4.72 ± 0.33, 12.30 ± 0.55, 12.72 ± 0.62, 8.74 ± 1.39, 9.47 ± 1.17, 11.83 ± 0.87, 14.44 ± 0.61 and 14.50 ± 0.67 mm, respectively. Plasma P4 concentrations on corresponding days were 0.49 ± 0.10, 3.16 ± 0.21, 5.18 ± 0.41, 3.01 ± 0.99, 3.50 ± 0.96, 5.66 ± 0.73, 8.54 ± 0.21 and 8.96 ± 0.15 ng/ml, respectively. The mean follicular size in heifers on days 0, 7, 14, 21, 23, 28, 35 and 42 post-AI was 12.70 ± 0.51, 5.86 ± 0.52, 5.23 ± 0.45, 9.21 ± 0.96, 7.41 ± 0.91, 6.14 ± 0.48, 4.80 ± 0.51 and 4.94 ± 0.30 mm, respectively. Plasma E2 concentrations on corresponding days were 56.08 ± 2.98, 29.58 ± 2.52, 20.25 ± 2.43, 38.08 ± 5.70, 22.66 ± 4.97, 21.58 ± 2.84, 15.80 ± 2.53 and 22.40 ± 3.29 pg/ml, respectively. Nearly similar values and trend of observations were recorded for CL/follicular size and plasma P4/E2 profile in postpartum cows. The values of CL size and plasma P4 were the lowest, and those of follicle size and plasma E2 were the highest on the day of estrus/AI, changed highly significantly (pless than0.01) by day 7 to 14, and again around day 21-23 and fluctuated at or little lower levels around day 35 and 42 post-AI. These trends were associated with recurrence of estrus in few animals around day 21-23, and establishment of pregnancy in others. No significant variation was noted in any of the traits between breeds and between parity at any of the intervals studied. Further, the conceiving and non-conceiving cows (irrespective of breed or parity) revealed identical pattern and values of all 4 traits (CL, Follicle, P4, E2) till day 14 post-AI, and there was significant drop in CL size/P4 and rise in follicular size/E2 profile in non-pregnant animals on day 21 post-AI due to initiation of next cycle. The mean concentration of blood glucose and plasma cholesterol recorded varied from 60.96 ± 1.69 to 68.67 ± 2.10 and 169.79 ± 1.43 to 181.01 ± 1.85 mg/dl, respectively, which did not vary significantly between breeds or intervals post-AI. The values of glucose and cholesterol were non-significantly higher in non-pregnant Gir and pregnant crossbred cattle as compared to their counter parts.
Therapeutic Efficacy of Different Ear Cleanser in Management of Canine Otitis
Authors: Parmar Jignasha  M. , Raval SK , Parwari Mayank , Rao Neha , Patel DM
Published: March 2020

The objective of this study was to compare the therapeutic efficacy of three different ear cleansers in 30 dogs of various breeds suffering from otitis. Based on history and clinical signs, ear exudates were collected by aseptic cotton swab for isolation and identification of organisms. The cerumen deposition in-ear canal was cleared using one of the ear preparations, viz., ear cleanser-I (0.2 % salicylic acid and 0.3 % phenoxyethanol) ear cleanser - II (chlorhexidine, propylene glycol and tris–EDTA) or ear cleanser-III (2% para-dichlorobenzene, benzocaine 2.7%, chlorbutol 5% and turpentine oil 15 %). Systemic/local antibiotics were used as per sensitivity testing. The treatment protocol found effective in the management of ear infections included cleaning the ear debris using ceruminolytic preparations/ear wax dissolvent, viz, ear drop. Ear cleanser-III showed excellent results (100%) in ceruminous as well as bacterial otitis with subsequent instillation of ear preparations containing antibacterial drug(s) and antifungal agents compared to cleanser-II (90%) and cleanser-I (70%).
Study on Clinico-Haematol-Biochemical Alterations in Goats Suffering from Trichostrongylosis in Anand District of Gujarat
Authors: Rajpura N R , Mandali G C , Rao Neha , Patel A C
Published: March 2020

This cross-sectional study was aimed at determining the effect of trichostrongylosis on clinical, hematological, and biochemical parameters in goats. The study included eight healthy control goats and 48 naturally infected goats from the Anand district of Gujarat. The cases having a history of diarrhea, anorexia, weakness, dullness, loss of weight, and not dewormed were selected. Fecal samples of infected goats were examined by direct smear method for the presence of Trichostrongylus spp. eggs and the infection was confirmed by quantitative evaluation and coproculture of the samples for the identification of larvae. The result indicated that the infected goats have significantly elevated rectal temperature, pulse rate, and respiration rate along with diarrhea, dullness, depression, emaciation, and loss of condition. Moreover, there was a significant decrease in the mean Hb, TEC, PCV, lymphocyes, as well as serum total protein, calcium and phosphorus, and a significant increase in TLC, neutrophils, eosinophils, ALT, AST and ALP in infected goats.
DALDIRMALI KAPLAMA SİSTEMİ İLE 2B MALZEMELERİN KAPLANMASI
Authors: SAĞLAM Özge
Published: March 2020

İki boyutlu (2B) malzeme ailesinin bir üyesi olan inorganik nanolevhalar bir ya da birkaç atom kalınlığına sahip olup yığın katmanlı oksit malzemelerin kimyasal olarak pullandırılması ile elde edilmektedir. Bu çalışmada, nanolevhalardan meydana gelen nanofilmlerin tabaka-tabaka yöntemi ile üretilmesi için bir daldırmalı kaplama sistemi tasarlanarak üretilmiştir. Sistemin nanofilm üretimindeki performansını test etmek amacıyla Nb6O17 nanolevhalar kullanılmıştır. Bunun için katmanlı K4Nb6O17·3H2O malzemesi pullandırılarak kalınlıkları yaklaşık 2 nm nanolevhalar elde edilmiştir. Daha sonra, negatif yüklü Nb6O17 nanolevhalar ve pozitif yüklü polidiallildimetilamonyum klorür (PDDA), otomatik daldırma sistemi kullanılarak kuartz alttaşlar üzerine dönüşümlü olarak yerleştirilmiştir. Nb6O17/PDDA’ in 5 kaplama döngüsüne sahip yüzey, atomik kuvvet mikroskobu ile taranarak alttaşın etkili şekilde kaplandığı görüntülenmiştir. Ayrıca, absorbans spektrası, Nb6O17/PDDA’ in çeşitli kaplama döngüleri için kaydedilmiştir. Daldırmalı kaplama sistemi ile elde edilen absorbans değerindeki artış literatürde raporlanmış manuel kaplama sonucunda elde edilen absorbans oranındaki artış ile kalitatif olarak benzer özellikler göstermiştir. Bu çalışmada önerilen düşük maliyetli ve laboratuvar ortamında geliştirilen sistemin de nanofilm kaplama araştırmalarında kullanılabileceği ortaya konmuştur.
A Novel Smartphone App for the Measurement of Ultra–Short-Term and Short-Term Heart Rate Variability: Validity and Reliability Study (Preprint)
Authors: Chen Yung-Sheng , Lu Wan-An , Pagaduan Jeffrey C , Kuo Cheng-Deng
Published: March 2020

BACKGROUND

Smartphone apps for heart rate variability (HRV) measurement have been extensively developed in the last decade. However, ultra–short-term HRV recordings taken by wearable devices have not been examined.

OBJECTIVE

The aims of this study were the following: (1) to compare the validity and reliability of ultra–short-term and short-term HRV time-domain and frequency-domain variables in a novel smartphone app, Pulse Express Pro (PEP), and (2) to determine the agreement of HRV assessments between an electrocardiogram (ECG) and PEP.

METHODS

In total, 60 healthy adults were recruited to participate in this study (mean age 22.3 years [SD 3.0 years], mean height 168.4 cm [SD 8.0 cm], mean body weight 64.2 kg [SD 11.5 kg]). A 5-minute resting HRV measurement was recorded via ECG and PEP in a sitting position. Standard deviation of normal R-R interval (SDNN), root mean square of successive R-R interval (RMSSD), proportion of NN50 divided by the total number of RR intervals (pNN50), normalized very-low–frequency power (nVLF), normalized low-frequency power (nLF), and normalized high-frequency power (nHF) were analyzed within 9 time segments of HRV recordings: 0-1 minute, 1-2 minutes, 2-3 minutes, 3-4 minutes, 4-5 minutes, 0-2 minutes, 0-3 minutes, 0-4 minutes, and 0-5 minutes (standard). Standardized differences (ES), intraclass correlation coefficients (ICC), and the Spearman product-moment correlation were used to compare the validity and reliability of each time segment to the standard measurement (0-5 minutes). Limits of agreement were assessed by using Bland-Altman plot analysis.

RESULTS

Compared to standard measures in both ECG and PEP, pNN50, SDNN, and RMSSD variables showed trivial ES (<0.2) and very large to nearly perfect ICC and Spearman correlation coefficient values in all time segments (>0.8). The nVLF, nLF, and nHF demonstrated a variation of ES (from trivial to small effects, 0.01-0.40), ICC (from moderate to nearly perfect, 0.39-0.96), and Spearman correlation coefficient values (from moderate to nearly perfect, 0.40-0.96). Furthermore, the Bland-Altman plots showed relatively narrow values of mean difference between the ECG and PEP after consecutive 1-minute recordings for SDNN, RMSSD, and pNN50. Acceptable limits of agreement were found after consecutive 3-minute recordings for nLF and nHF.

CONCLUSIONS

Using the PEP app to facilitate a 1-minute ultra–short-term recording is suggested for time-domain HRV indices (SDNN, RMSSD, and pNN50) to interpret autonomic functions during stabilization. When using frequency-domain HRV indices (nLF and nHF) via the PEP app, a recording of at least 3 minutes is needed for accurate measurement.
A Guide to Chatbots for COVID-19 Screening at Pediatric Health Care Facilities (Preprint)
Authors: Espinoza Juan , Crown Kelly , Kulkarni Omkar
Published: March 2020

UNSTRUCTURED

The coronavirus disease 2019 (COVID-19) outbreak has required institutions to rapidly adapt to changing public health circumstances. The Centers for Disease Control and Prevention has encouraged health care facilities to explore novel health care delivery modes. However, many institutions may not be prepared to begin offering digital health and telehealth services. Chatbots are one digital health tool that can help evolve triage and screening processes in a scalable manner. Here, we present a decision-making and implementation framework for deploying COVID-19 screening chatbots at pediatric health care facilities.
IMIDACLOPRID TOXICITY AND ITS ATTENUATION BY AQUEOUS EXTRACT OF MORINGA OLEIFERA LEAF IN ZEBRA FISH, DANIO RERIO
Authors: YADAV VINEETA , AHMAD SHADAB , ZAHRA KANEEZ
Published: March 2020

Objective: Imidacloprid (IMC) is a systemic chloro-nicotinyl insecticide that is applied in crop fields to control a wide variety of harmful insects and pests. The objective of the present study was to evaluate the mitigating effects of Moringa leaf extract (MLE) against Imidacloprid (IMC) induced mortality after acute toxicity bioassay in zebrafish, Danio rerio.

Methods: The fishes were exposed to various concentrations of IMC to estimate the LC50 values at different exposure periods using the probit analysis.

To assess the attenuating effect on mortality fishes were exposed to different concentrations of MLE along with 24 and 96 h LC50 of IMC. Mortality rate of fishes was recorded during all experimental periods.

Results: The LC50 values were found to be 0.423, 0.352, 0.297 and 0.270 ml/l after 24, 48, 72 and 96 h respectively. The upper confidence limits were 0.491, 0.408, 0.334 and 0.302 ml/l and lower confidence limits were 0.355, 0.296, 0.260 and 0.238 ml/l for 24, 48, 72 and 96 h respectively.

The fishes remain alive at 12 ml/l and 10 ml/l of MLE against 24 and 96 h LC50 respectively. Some behavioral responses such as violent, sluggish and erratic movement, respiratory distress, mucous secretion all over the body, discoloration were also observed in IMC treated fishes in comparison to MLE treated fishes.

Conclusion: These findings demonstrated that MLE has mitigating effects against the toxic influence of IMC on mortality in zebra fishes which is attributed to its antioxidant effects.
SPECTROPHOTOMETRIC DETERMINATION OF DASATINIB IN PHARMACEUTICAL FORMULATIONS
Authors: THORAT YOGESH , SHEGAONKAR ANITA , KUMBHAR SMITA , MATOLE VINOD , HOSMANI AVINASH
Published: March 2020

Objective: A new, simple, sensitive, precise and reproducible bioanalytical method was developed for the determination of Dasatinib in pharmaceutical formulations with Chloranilic acid.

Methods: The method is based on formation of violet colored complex. The UV spectrum of Dasatinib in methanol showed λ max at 521 nm. Beer’s law is valid in the concentration range of 10-60 μg/ml. This method was validated for linearity, accuracy, precision, ruggedness and robustness.

Results: The method has demonstrated excellent linearity over the range of 10-60 μg/ml with regression equation y = 0.021x-0.083 and regression correlation coefficient r2= 0.997. Moreover, the method was found to be highly sensitive with LOD (2.96μg/ml) and LOQ (8.98μg/ml).

Conclusion: Based on results the proposed method can be successfully applied for the assay of Dasatinib in various pharmaceutical dosageforms.
THE EFFECTS OF HONEY ADMINISTRATION ON SOLUABLE FMS-LIKE TYROSINE KINASE (SFLT-1), SOLUBLE ENDOGLIN (S-ENG), VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) SERUM LEVELIN THE RAT MODEL OF PREECLAMPSIA
Authors: ASROEL EDWIN MARTIN , MAAT SOEPRAPTO , SITEPU MAKMUR , ILYAS SYAFRUDDIN
Published: March 2020

Objective: To find out the effect of honey administration on changes in antiangiogenic and proangiogenic serum levels in the rat model of preeclampsia. This study is the first research that examines the effect of honey on preeclampsia especially on proangiogenic and antiangiogenic factors

Methods: This study uses analytic research with a quasi-experimental design in laboratory rats (Rattus Norvegicus) pregnant females given honey with concentration. The treatment of all samples was carried out simultaneously and during the treatment it was observed using the type of postest only control group design.

Results: Honey administration significantly reduced sFlt-1 levels in preeclampsia rats, and a greater dose of honey had an effect on strengthening the effect of honey in reducing sFlt-1 levels. Honey administration significantly increased VEGF levels in preeclampsia mice (p = 0.034). Honey administration significantly decreased s-Eng levels in preeclampsia mice, and administration of a larger dose of honey had an effect on strengthening the effect of honey in reducing s-Eng levels (p = 0.012).

Conclusion: The honey administration on rat’s model of preeclampsia may reduce the antiangiogenic level sFlt-1 and sEng dan increase VEGF level as the pro-angiogenic
EVALUATION OF TOTAL POLYPHENOLS AND ANTIOXIDANT CAPACITY IN MUSHROOM EXTRACTS PLEUROTUS OSTREATUS AND LENTINULA EDODES
Authors: GARCIA IVAN MARCELO , S. ARTURO ROJAS , MONTERO DANILO , ARELLANO MARCO
Published: March 2020

Objective: This research was aimed at assessing the concentration of total polyphenols in ethanolic and methanolic extracts of Pleurotus ostreatus and Lentinula edodes mushrooms and antioxidant activity.

Methods: Polyphenols were determined by the Folin Ciocalteu method, using lyophilized mushroom samples for the preparation of extracts and antioxidant activity by the TBARS method.

Results: Extracts prepared from mushrooms showed appreciable values ​​of polyphenols, and for the ethanolic extract of Pleurotus ostreatus and Lentinula edodes values ​​of 102.78 and 81.83 mg of gallic acid/100 g of the sample respectively, comparable to those obtained in some fruits For methanolic extracts, values ​​of 100.45 and 78.92 mg of gallic acid/100 g of sample were obtained. Polyphenol concentration values ​​for the Pleurotus were higher in the two types of extracts and lower for the Lentinula edodes.

Conclusion: When evaluating the antioxidant activity, high antioxidant activity was found for the two types of mushroom, Pleurotus ostreatus and Lentinula edodes, presenting peroxidase inhibition values ​​of 88.04 and 89.49% respectively.
DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRICMETHOD FOR QUANTITATIVE ESTIMATION OF GLIPIZIDEIN PHARMACEUTICAL DOSAGE FORM
Authors: SURYAWANSHI ANUJA , AFAQUEANSARI  , KALSHETTI MALLINATH
Published: March 2020

Objective: The present work is aimed to develop a simple, rapid, selective and economical UV spectrophotometric method for quantitative determination of Glipizideinbulk and pharmaceutical dosage form.

Methods: In this method Dimethyl Form amide (DMF) was used as solvent, the absorption maxima was found to be275 nm in DMF. The developed method was validated for linearity, accuracy, precision, ruggedness, robustness, LOD and LOQ in accordance with the requirements of ICH guideline.

Results: The linearity was found to be 10-60 µg/ml having linear equation y=0.017x-0.006 with correlation coefficient of 0.997. The% recovery was found to be in the range of 98.7-100%. The % RSD for intra-day and inter-day precision was found to be 0.569923 and 0.40169 respectively. The limit of detection (LOD) and limit of quantification (LOQ) was found to be3.06 µg/ml and 9.27 µg/ml respectively.

Conclusion: The developed method was validated as per ICH Q2(R1) guidelines. The novel method is applicable for the analysis of bulk drug in its pharmaceutical dosage form.
Historias congeladas en el hielo polar
Authors: Murray-Tortarolo Guillermo N.
Published: March 2020

"Hielo… Raramente pensamos en él si no es para enfriar el agua de limón o el refresco. No obstante, cubre una décima parte de la superficie de nuestro planeta. Lejos de ser estático, el hielo guarda historias en las partículas de polvo y las burbujas que quedan atrapadas en su interior. En particular, la nieve de los casquetes polares y los glaciares ha retenido la historia de nuestra humanidad, de la vida, de la evolución de nuestro planeta y hasta del espacio.

En este artículo te contaré un par de las muchas, muchas historias que se encuentran congeladas en los hielos perpetuos terrestres. Primero, te llevaré a las partículas de plomo atrapadas en el Polo Norte y te hablaré de cómo reconstruyen la historia de nuestra humanidad. Después, daremos un salto espacial y te diré la manera en que el berilio congelado nos ayuda a entender la historia de nuestro Sol. Finalmente, conoceremos el riesgo que el cambio climático implica para este recurso histórico y la memoria que podríamos perder si el hielo polar se derrite."
Innovar en compañía: el Repositorio de Innovación Educativa de la UNAM
Authors: Santos Solórzano Roberto , González Flores Patricia
Published: March 2020

Este artículo describe el Repositorio de Innovación Educativa -una plataforma digital que da acceso a diversos recursos y productos sobre innovación educativa- como un mecanismo que busca facilitar la sistematización y visibilización de las innovaciones educativas que se realizan en la Universidad Nacional Autónoma de México (unam). Además, se aborda la importancia de la innovación, y los retos y dificultades para implementarla en el contexto universitario. Por último, se exponen las fortalezas de innovar en colaboración y el papel que la Coordinación de Desarrollo Educativo e Innovación Curricular (codeic) de la unam asume en este fin.
“De ces cartes on verra surgir les lois de la distribution des styles d’Architecture.” Cartografiar la historia de la arquitectura en el siglo XIX (II): Arcisse de Caumont y los mapas pasigráficos
Authors: Girón Sierra Javier
Published: March 2020

(en proceso)
PROBLEMS OF THE FIGHT AGAINST CRIME IN THE XXI CENTURY: CRIMINAL LAW, CRIMINAL PROCEDURE AND CRIMINALISTICS DECISIONS
Authors: Klebanov Lev R.
Published: March 2020

-
EVALUASI FASILITAS PADA RUANG PUBLIK BAGI PENYANDANG DISABILITAS TUNA DAKSA (Studi Kasus: Stasiun Pondok ranji)
Authors: Putra Pristian Irvana , Widajanti Andjar
Published: March 2020

ABSTRAKStasiun kereta api sebagai salah satu fasilitas umum penunjang aktifitas yang diperuntukan sebagai seluruh golongan masyarakat.Kelayakan fasilitas umum yang sesuai dengan standart yang berlaku menjadi hal yang perlu diperhatikan ketika merancang suatu sarana fasilitas publik, terutama bagi penyandang disabilitas tuna daksa yang tentu memerlukan standart khusus agar dapat menggunakan maupun mengakses suatu fasilitas publik. Tujuan penelitian ini adalah untuk mengevaluasi fasilitas aksesibilitas bagi penyandang disabilitas tuna daksa di Stasiun Pondok Ranji, sehingga nantinya dapat diketahui apakah fasilitas aksesibilitas bagi penyandang disabilitas tuna daksa di Stasiun Pondok Ranji sudah sesuai atau belum sesuai dengan standart yang berlaku. Metode yang dilakukan dalam penelitian ini yaitu menggunakan metode kualitatif berupa observasi langsung dilapangan yang nantinya diolah menggunakan metode perbandingan dengan mengacu pada standart yang berlaku. Hasil yang didapatkan dari penelitian ini dapat disimpulkan bahwa fasilitas aksesibilitas bagi penyandang disabilitas tuna daksa di Stasiun Pondok Ranji belum sesuai dengan standart yang berlaku.Kata Kunci :   Tuna Daksa, Fasilitas Publik, Disabilitas, Stasiun ABSTRACTThe station as one of the public facilities supporting activities which is intended as a whole class of society. The feasibility of public facilities in accordance with applicable standards is something that needs to be considered when designing a public facility, especially for people with disabilities who certainly require special standards in order to use or accessing a public facility. The purpose of this study was to evaluate accessibility facilities for people with disabilities at Pondok Ranji Station, so that later it can be known whether the accessibility facilities for people with disabilities at Pondok Ranji Station are appropriate or not in accordance with the applicable standards. The method used in this research is using a qualitative method in the form of direct observation in the field which will be processed using a comparison method with reference to the applicable standard. The results obtained from this study can be concluded that the accessibility facilities for people with disabilities in Pondok Ranji Station are not in accordance with the applicable standards.Keyword: Disabilities, Public Facilities, Train Station
TIPOMORFOLGI PERUBAHAN BENTUK DAN FUNGSI SATUAN RUMAH SUSUN SEDERHANA MILIK THE GOLF APARTMENT MODERENLAND
Authors: Sufani Esa , Hardi Joni
Published: March 2020

ABSTRAK Minimnya lahan kosong di perkotaan membuat banyaknya permukiman kumuh, sehingga pemerintah memberikan solusi dengan dibangunnya rumah susun sederhana. Akan tetapi dalam penempatannya, banyak penghuni yang merasa tidak nyaman dengan desain yang telah dibuat oleh pengembang atau pemerintah pada unit hunianya. Sehingga terjadilah perubahan pada unit huniannya untuk memberikan rasa nyaman pada penguninnya. Begitu pula yang terjadi pada rumah susun The Golf Apartment Modernland terdapat beberapa perubahan yang terjadi pada unt huniannya. Penelitian ini dilakukan untuk melihat perubahan apa saja yang terjadi dan apa faktor yang mendorong perubahan itu terjadi. Sebagai sampel penelitian ini diambil 30 unit yang telah dihuni selama 4 tahun. Metode yang digunakan pada penelitian ini adalah kuantitatif dengan menggunakan  dasar  teori  N.J  Habraken  dengan  pengumpulan  data  melalui  observasi  dan kusioner. Hasil dari penelitian ini menunjukan bahwa layout yang telah ada sudah baik karena tidak banyak  perubahan  yang  terjadi  dan  perubahan  paling  banyak  adalah  akibat  faktor  stailistik sehingga pemerintah dapat membuat beberapa pilihan kepada penghuni agar tidak terjadinya perubahan. Kata Kunci :  Tipomorfologi, Perubahan, Rumah Susun, N.J Habraken  ABSTRACT The lack of vacant land in the city makes a lot of slums, so the government provides a solution with the construction of simple flats. However, in its placement, many residents feel uncomfortable with the design that has been made by the developer or the government in its residential unit. So that there was a change in the housing unit to provide comfort to the occupants. Likewise, what happened to the apartment apartment in The Golf Apartment Modernland, there were a number of changes that occurred in the housing complex. This research is conducted to see what changes occur and what factors that drive change occur. As a sample, this study was taken 30 units that have been occupied for 4 years. The method used in this study is quantitative using the basis of N.J Habraken's theory by collecting data through observation and questionnaire. The results of this study indicate that the existing layout is good because there are not many changes that occur and most changes are due to statistical factors so that the government can make several choices for residents to avoid changes. Keyword: Typomorphology, Change, Flats, N.J Habraken
Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas
Authors: Dybala Michael P. , Kuznetsov Andrey , Motobu Maki , Hendren-Santiago Bryce K. , Philipson Louis H. , Chervonsky Alexander V. , Hara Manami
Published: March 2020

The pancreatic islet is a highly vascularized endocrine micro-organ. The unique architecture of rodent islets, a so-called core-mantle arrangement seen in two-dimensional images, led researchers to seek functional implications for islet hormone secretion. Three models of islet blood flow were previously proposed, all based on the assumption that islet microcirculation occurs in an enclosed structure. Recent electrophysiological and molecular biological studies using isolated islets also presumed unidirectional flow. Using intravital analysis of the islet microcirculation in mice, we found that islet capillaries were continuously integrated to those in the exocrine pancreas, which made the islet circulation rather open, not self-contained. Similarly in human islets, the capillary structure was integrated with pancreatic microvasculature in its entirety. Thus, islet microcirculation has no relation to islet cytoarchitecture, which explains its well-known variability throughout species. Furthermore, tracking fluorescent-labeled red blood cells at the endocrine-exocrine interface revealed bidirectional blood flow, with similar variability in blood flow speed in both the intra- and extra-islet vasculature. To date, the endocrine and exocrine pancreas have been studied separately by different fields of investigators. We propose that the open circulation model physically links both endocrine and exocrine parts of the pancreas as a single organ through the integrated vascular network.
Isı Borulu-Isı Geri Kazanım Ünitesinde ZnO/Su ve ZnOAl2O3/Su Nanoakışkanları Kullanılarak Performansın İyileştirilmesi
Authors: AYTAÇ İpek , SÖZEN Adnan
Published: March 2020

Endüstride ve birçok atık ısı tesislerinde kullanılan atık ısı geri kazanım üniteleri gerekli temiz havanın ön ısıtılmasında kullanılan sistemlerdir. Bu çalışmada ısı değiştiricisi ısı borusu olan bir ısı geri kazanım ünitesinin performansının iyileştirilmesi ve böylece çalışma sıcaklık aralığının arttırılması amacıyla oluşturulan deney düzeneği üzerinde uygulamalı bir çalışma yapılmıştır. Çalışmanın özgün yanı ısı değiştiricisi olarak kullanılan ısı borularında son yıllarda pek çok uygulama olanağı bulan nanoakışkanların kullanılması hedeflenmiştir. ZnO/Su ve ZnOAl2O3/Su nanoakışkanları ısı borusunda çalışma akışkanı olarak kullanılmış ve temel akışkan suya göre ısı geri kazanım ünitesi ısıl performansındaki iyileşme oranları belirlenmeye çalışılmıştır. Soğuk hava bölgesinde (kondenser), soğuk hava hızı 0.437m/s ve Re=7100 olduğunda ZnOAl2O3 ve ZnO nanoakışkanları için sırasıyla %90 ve %80 oranında iyileşme elde edilmiştir.
Ryssland och historiens början
Authors: Flikke Geir
Published: March 2020

Abstract in English:Russia and the Beginning of HistoryMorgan Olofsson's Russia and the Beginning of History consists of several interviews that the former Swedish news correspondent made with people he met in the 1990s. The purpose, he says, is to see how people have fared in the timespan from the 1990s to 2018, but also, more ambitiously, to sustain a dialogue between people on topics like the gradual dissemination of authoritarian political systems. Olofsson argues that we "need to learn from history" to protect democratic values; that is, values that connect people. The structure of the book is reminiscent of Mikhail Zygar's All the Kremlin's Men (2016), short annotated chapters, with introductions. The interviews stand out as sharp and perceptive, but the structure and editing of the book leaves more to be desired.
UNDERSTANDING LEVEL OF FARMERS ON THE USE OF THE INTEGRATED LIVESTOCK AREA IN NGGORANG VILLAGE, KOMODO DISTRICT, WEST MANGGARAI IN EAST NUSA TENGGARA
Authors: Detha Annytha -
Published: March 2020

The purpose of this community service activity is to support the Agro Tourism of Nggorang Village, Komodo District, West Manggarai to maximize the productivity of cattle farms by utilizing the availability of natural resources while empowering rice straw agricultural waste as the main source of feed by utilizing feed processing technology, creating a healthy environment in the village by supporting Agroeduwisata village and clean grazing center through the utilization of livestock feces waste into organic fertilizer using natural probiotics, which have an impact on environmental cleanliness. In achieving this goal, there are a number of methods for achieving the objectives, namely the active participation approach of the community in collaboration with the village component starting from the planning stage, including data collection and mapping of available resources; implementation phase; the monitoring and evaluation phase of the activities to ensure the achievement of all aspect of the objectives. Based on the results obtained in this activity, there is an understanding of the benefits and advantages of integrated grazing land that can be applied by farmers in Desa Nggorang village, Komodo District, West Manggarai in NTT
Síndrome de Wolfram en uno de cuatro hermanos: caso reporte
Authors: Chávez Cinthya , Cedeño Roberto , Amador Jorge , Valdivieso Sonia
Published: March 2020

El síndrome de Wolfram es una patología degenerativa, neuroendocrina, cuya sospecha diagnostica se debe plantear ante un sujeto joven con diabetes mellitus (DM) y atrofia óptica (1) que deberá ser confirmado con el estudio genético (2). Se conoce como síndrome de DIDMOAD debido a que asocia DM, diabetes insípida, atrofia óptica y sordera (3); se ha sugerido la denominación DIDMOADUA por la alta frecuencia de trastornos urológicos; además suelen existir manifestaciones a nivel neurológico, psiquiátrico y gonadal (4). El pronóstico es malo, no existiendo tratamiento curativo identificado hasta el momento, el promedio de vida es de 30 años y las manifestaciones neurológicas especialmente la atrofia del tronco cerebral constituyen la causa de muerte (5). Presentamos el caso de un paciente que reúne criterios clínicos diagnósticos definitivos de síndrome de Wolfram, con el objetivo de describir una patología que es rara, y por ende concientizar en su detección temprana, para que el paciente alcance una mejor calidad de vida.
The Other Robinson
Authors: De Zulueta Elisina
Published: March 2020

A genealogy of Robinson; Robinson Crusoe considered as a recursive mode of producing existential territory.
‘I Looked and Beheld a Country’: Home Movies, Homesteads and the Family Archive
Authors: Rathbone Daniel Clayton
Published: March 2020

Home movies, like family photographs, are important parts of family life, acting as ways to frame the idea of the family and connect different, inter-generational memories together. Footage of key moments helps develop a family identity, as well as locate it within broader historical contexts. As a result, home movies provide an incredibly useful source with which to examine the intersections between narratives of the family, nation and belonging. Utilising a collection of personal home movies, this paper will explore how these themes are touched on within the context of British Colonial Southern Africa. These films explore how ideas of family identity are rooted within ideas of home and belonging, articulating a conceptualisation of colonial Southern Africa as a ‘home-scape’ for descendant of British settlers living there during the 1950s and 1960s. These home movies draw attention to the creation of the idea of home and family, while also producing disruptive elements to those narratives.
INDONESIA FOOD SECURITY POLICY ON IMPORT CATTLE AND MEAT AUSTRALIA YEARS 2013-2017
Authors: Abdal Abdal , Nurdin Ismail
Published: March 2020

Food is an essential human need and its fulfilment is part of human rights guaranteed by the constitution so that it has a strategic place in national development. However, if domestic food sources cannot meet national needs, then food imports can be carried out. Cattle and beef imports are carried out by Indonesia in order to meet Indonesia's food security policy. This study aims to describe and analyze how Indonesia's food safety policy in importing cattle and beef from Australia in 2013-2017. The research method used is a qualitative method with the type of descriptive research that aims to describe in detail and accurately and to deepen the meaning of research related to Indonesia's food security policy in Australian beef and beef imports. Data collection techniques with observation, in-depth interviews, and study documentation. The results show that Indonesia's policy to import Australian cows and beef is a liberal economic model, where the main role of imports is importing entrepreneurs, while the government as an import regulator has an interest in ensuring the fulfilment of three aspects of food security, namely food availability; affordability of food access; and affordability of prices; As for the other causes, Indonesia imports cows and beef from Australia due to political reasons.
Analysis of the impact of domestic socio-economic characteristics on child education in rural households
Authors: Herdiyanti Herdiyanti
Published: March 2020

The study titled Impact Analysis Characteristics of domestic socio-economic and child education in households in South Bangka district, this refers to the prestigious University of Bangka Belitung with the theme empowerment and strengthening Local community modalities, especially on the topic of increasing public participation on education in Bangka Belitung. The main challenge of the labor market in Bangka Belitung is the fulfillment of a more competent workforce, especially in the formal sector. This research is expected to give a real picture of the main condition causing low participation of schools in several villages in South Bangka from the side of the household. This research uses an Ordinary method of Least Square research that explains the influence of the characteristics of socio-economic households towards child education is found that the rate of household income precisely does not affect the long School children. The results showed that the age of the household head and the ratio of household dependencies had a positive influence on child education. This is in connection with work that is usually managed informally on households living in rural areas. The number of dependent households (14 to 64 years) is not going to work when the number of households in the product family is quite a lot. Keywords: Children's education, household socio-economic.
STATUS KEBERSIHAN MULUT BERDASARKAN INDEKS ORAL HYGIENE INDEX SIMPLIFIED (OHI-S) PADA SISWA SEKOLAH USIA 9, 10 DAN 11 TAHUN
Authors: Anwar Ayub Irmadani , Abdat Munifah , Ayub Aldy Anzhari , Yusrianti Meilisa
Published: March 2020

Penyakit gigi dan mulut di Indonesia umumnya terkait dengan masalah kebersihan mulut. Salah satu penyebab masalah kesehatan gigi dan mulut di masyarakat adalah faktor perilaku yang mengabaikan kebersihan gigi dan mulut. Penelitian ini bertujuan untuk untuk memperoleh gambaran mendalam dari status kebersihan rongga mulut pada siswa sekolah usia sembilan, sepuluh, dan sebelas tahun. Metode penelitian ini dengan jenis penelitinan observasional deskriptif dengan desain cross sectional. Penelitian dilakukan di Sekolah Dasar Negeri Mattoangin I dan Sekolah Dasar Inpres Bertingkat Kota Makassar, Sulawesi Selatan. Hasil penelitian ini menunjukkan bahwa status kebersihan gigi dan mulut siswa dikategorikan sebagai kriteria baik. Berdasarkan jenis kelamin menunjukkan nilai rata-rata DI-S yang lebih tinggi diperoleh pada siswa laki-laki dibandingkan dengan siswa perempuan. Nilai rata-rata CI lebih tinggi pada siswa perempuan dibandingkan dengan siswa laki-laki. Nilai  rata-rata OHI-S tertinggi ditemukan pada siswa laki-laki dibandingkan dengan siswa perempuan. Kesimpulan penelitian ini bahwa berdasarkan OHI-S, siswa berada dalam kriteria yang baik, dan kelompok usia sebelas tahun dalam kriteria menengah. Tingkat kebersihan mulut didasarkan pada OHI-S dimana siswa laki-laki dan siswa perempuan dalam kriteria yang baik.Kata kunci : Status Oral Hygiene, DI-S, CI-S, OHI-S
ANALISIS PERMUKAAN RESIN KOMPOSIT NANOFILLER SETELAH PERENDAMAN DALAM MINUMAN BERSODA DAN MINUMAN KEMASAN RASA JERUK
Authors: Diansari Viona , Sundari Iin , Siregar Hariyanti
Published: March 2020

Resin komposit jenis nanofiller memiliki sifat fisik dan mekanik yang lebih baik dari jenis resin komposit lain. Paparan asam secara terus-menerus dalam waktu lama mengakibatkan perubahan mikrostruktur yang berpengaruh pada sifat fisik dan mekanik resin komposit. Penelitian ini bertujuan mengamati gambaran Scanning Electron Microscope (SEM) permukaan resin komposit nanofiller sebelum dan setelah perendaman dalam minuman bersoda dan minuman kemasan rasa jeruk. Sebuah penelitian eksperimental laboratoris yang menggunakan 4 spesimen dibagi dalam 2 kelompok perlakuan. Kelompok 1 perendaman dalam minuman bersoda (cola) dan kelompok 2 perendaman dalam minuman kemasan rasa jeruk (Buavita jeruk). Spesimen direndam selama 6 hari yang setara dengan konsumsi cola dan buavita selama 1,5 tahun. Perubahan mikrostruktur permukaan resin komposit nanofiller diamati menggunakan Scanning Electron Microscope Hitachi TM3000. Gambaran SEM mikrostruktur permukaan resin komposit dianalisis secara kualitatif kemudian dihitung jumlah porus dan dianalisis menggunakan Paired t-test dan Unpaired t-test. Hasil analisis paired t-test menunjukkan perbedaan bermakna antara jumlah porus sebelum dan setelah perendaman dalam cola dan buavita jeruk. Hasil analisis Unpaired t-test menunjukkan perbedaan yang tidak bermakna antara jumlah porus dalam perendaman cola dan buavita jeruk. Disimpulkan bahwa minuman bersoda dan kemasan rasa jeruk, keduanya, dapat menyebabkan terjadinya perubahan mikrostruktur permukaan resin komposit nanofiller berupa peningkatan jumlah porus.Kata kunci: Resin komposit nanofiller, Scanning Electron Microscope, porusitas
PERAN EKSTRAK DAUN WUNGU (GRAPTOPHYLLUM PICTUM L. GRIFF) TERHADAP ADHESI STREPTOCOCCUS MUTANS PADA NEUTROFIL
Authors: Kurniawati Atik , - Sulistiyani , Rahmah Arina Nur
Published: March 2020

Streptococcus mutans (S. mutans) merupakan bakteri utama penyebab karies gigi yang mampu mendemineralisasi email, menginvasi dentin yang dapat berlanjut menjadi inflamasi pulpa (pulpitis). Streptococcus mutans menginvasi inang diawali dengan melakukan adhesi (perlekatan). Proses ini merupakan langkah awal dalam proses inflamasi. Oleh karena itu, adhesi Streptococcus. mutans pada sel inang perlu dicegah agar tidak terjadi infeksi oleh bakteri. Neutrofil merupakan sel pertahanan pertama yang datang pada proses inflamasi. Salah satu upaya untuk mencegah terjadinya adhesi tersebut bisa menggunakan bahan alami yang bersifat anti-inflamasi, salah satunya yaitu daun wungu. Penelitian ini bertujuan untuk  mengetahui pengaruh pemberian ekstrak daun wungu (EDW) terhadap adhesi  bakteri  Streptococcus. mutans pada neutrofil dan perbedaan indeks adhesi dalam berbagai konsentrasi dengan eksperimental laboratoris menggunakan the post test only control group design. Sampel terbagi menjadi 5 kelompok (klp): klp I/kontrol (tanpa inkubasi EDW), klp II (EDW 3,125%), klp III (EDW 6,25%), klp IV (EDW 12,5%), dan klp V (EDW 25%). Isolat neutrofil diinkubasi dengan EDW selama 3 jam, kemudian dipapar S. mutans selama 4 jam. Indeks adhesi dihitung berapa rata-rata jumlah S. mutans  yang menempel pada 100 neutrofil. Simpulan penelitian menunjukkan bahwa ekstrak etanol daun wungu berpotensi menurunkan indeks adhesi Streptococcus mutans. Kata kunci: adhesi, S. mutans, neutrophil, daun wungu