bluuebunny/crossref_metadata_2025 huggingface dataset:
The Supersymmetry Genetic Code Table and Quadruplet Symmetries of DNA Molecule Are the Unchangeable and Synchronized with the Codon Free Energy Mapping during Evolution
Authors: Rosandic Marija , Paar Vladimir
Published: October 2023

The Supersymmetry Genetic code (SSyGC) table is based on five physicochemical symmetries: 1) double mirror symmetry on the principle of the horizontal and vertical mirror symmetry axis between all bases (purines [A, G) and pyrimidines (U, C)], and 2) of bases in form of codons 3) direct – complement like codon/anticodon symmetry in the sixteen alternating boxes of the genetic code columns, 4) A+T rich and C+G rich alternate codons in the same row between both columns of the genetic code, 5) the same position between divided and undivided codon boxes in relation to horizontal mirror symmetry axes. The SSyGC table has a unique physicochemical purine – pyrimidine symmetry net which is as the core symmetry common for all, more than thirty different nuclear and mitochondrial genetic codes. This net is present in the SSyGC table of all RNA and DNA living species. None of these symmetries is present in the Standard Genetic Code (SGC) table which is constructed on the alphabetic horizontal and vertical U-C-A-G order of bases. Here we show that the free energy value of each codon incorporated as fundamentally mapping the “energy code” in the SSyGC table is compatible with mirror symmetry. On the other hand, in the SGC table the same free energy values of codons are dispersed and a mirror symmetry between them is not recognizable. At the same time the mirror symmetry of the SSyGC table and the DNA quadruplets together with our classification of codons/trinucleotides are perfectly imbedded in the mirror symmetry energy mapping of codons/trinucleotides and point out in favor of maintaining the integrity of the genetic code and DNA genome. We also argue that physicochemical symmetries of the SSyGC table in the manner of the purine – pyrimidine symmetry net, the quadruplet symmetry of DNA molecule and the free energy of codons have remined unchanged during all of evolution. The unchangeable and universal symmetry properties of the genetic code, DNA molecule and energy code are decreasing disorder between codons/trinucleotides and shed a new light on evolution. Diversity in all living species on Earth is broad, but the symmetries of the Supersymmetry Genetic Code as the code of life and the DNA quadruplets related to the” energy code” are unique, unchangeable and have the power of natural laws.
An automatic pixel-wise multi-penalty approach to image restoration
Authors: Bortolotti Villiam , Landi Germana , Zama Fabiana
Published: October 2023

This work tackles the problem of image restoration, a crucial task in many fields of applied sciences, focusing on removing degradation caused by blur and noise during the acquisition process. Drawing inspiration from the multi-penalty approach based on the Uniform Penalty principle introduced in [Bortolotti et al. arXiv.math.NA/2309.14163], we develop here a new image restoration model and an iterative algorithm for its effective solution.
The model incorporates pixel-wise regularization terms and establishes a rule for parameters selection, aiming to restore images through the solution of a sequence of constrained optimization problems. To achieve this, we present a modified version of the Newton Projection method, adapted to multi-penalty scenarios, and prove its convergence. Numerical experiments demonstrate the efficacy of the method in eliminating noise and blur while preserving the image edges.
Reducing the Risk of Birth Defects Associated with Maternal Influenza: Insights from a Hungarian Case-Control Study
Authors: Mátrai Ákos , Teutsch Brigitta , Pethő Boglárka , Kaposi András D. , Hegyi Péter , Acs Nandor
Published: October 2023

Influenza virus can cause several complications during pregnancy. Therefore, we aimed to inves-tigate the effects of influenza on the development of congenital abnormalities (CAs) by analyzing the database of the Hungarian Case-Control Surveillance of Congenital Abnormalities (HCCS-CA). In our multicenter, case-control, population-based study, we processed clinician-reported outcomes and diagnoses collected in the HCCSCA. The case group included newborns with dif-ferent non-chromosomal birth defects, while controls were newborns without CAs. Maternal in-fluenza, as a risk factor for CAs, was analyzed by using a logistic regression model and odds ra-tios with 95% confidence intervals (CIs). Our results showed that maternal influenza in the first trimester was associated with increased odds of developing non-chromosomal CAs (OR: 1.41, CI: 1.28–1.55). There were increased odds of neural tube defects (OR: 2.22, CI: 1.78–2.76), orofacial clefts (OR: 2.28, CI: 1.87–2.78) and congenital heart defects (OR: 1.28, CI: 1.10–1.49) after influenza infection. In all cases, we found a protective effect of folic acid supplementation in the first tri-mester. The odds of non-chromosomal birth defects are higher after maternal influenza in the first -trimester. Folic acid or pregnancy vitamin supplementation and antipyretic therapy may reduce the effect of maternal influenza during the first trimester.
Printability Properties of Protein Gel Obtained from Mealworm (Tenebrio molitor) in the 3D Food Printing of Deep-Space Food
Authors: Chancharoen Wares , Kaewkumpha Yossaphol , Chansataporn Wanassanan , Ngamkajornwiwat Potiwat , Wannakee Jirapat
Published: October 2023

Increasing the availability of alternative protein from insects is important to solving food shortages. Not only are insects a rich source of protein, the use of insect ingredi-ents can reduce food waste. Insects are thus a potentially valuable ingredient for food industries and even food eaten on deep-space missions. The three-dimensional produc-tion of food on space missions has gained attention owing to its potential to reduce au-tonomous food production and produce sustainable food for long-duration space mis-sions. This study investigated the printability and rheological properties of a high-protein food system derived from mealworms and guar gum used as a stabilizer to im-prove printability. Stability and rheological properties were analyzed for various print-ing parameters. The results indicate that as the guar gum concentration was increased from 0 to 1.75%, the yield stress of the mealworm paste increased from 39 to 1096 Pa. Increasing the guar gum concentration thus resulted in a mealworm paste that was more viscous, exhibited shear thinning behavior, could support itself and was thus more stable. In summary, introducing guar gum resulted in a mealworm paste with rheological properties more suitable for printing in terms of printability and stability.
Teasing apart tense-related encoding and retrieval deficits in aphasia: Evidence from Greek, Russian, Italian and English
Authors: Fyndanis Valantis , Burgio Francesca , Buivolova Olga , Danesin Laura , Gardner Qingyuan , Kalpakidi Theodora , Scimeca Michael , Soilemezidi Marielena , Swathi Kiran , Dragoy Olga
Published: October 2023

Persons with stroke-induced aphasia (PWAs) are often impaired in tense/time reference (TR) production. It is not clear, however, whether PWAs’ impaired TR production is due to TR-related encoding or retrieval deficits. This study aims at disentangling TR-related encoding deficits from TR-related retrieval deficits in aphasia. Two sentence completion tasks (SCTs) tapping production of past and future reference were administered to eight Greek-speaking PWAs, eight Russian-speaking PWAs, six Italian-speaking PWAs, seven English-speaking PWAs and four groups of language-, age- and education-matched healthy controls. SCT 1 tapped TR-related encoding processes and TR-related retrieval processes to a similar extent. SCT 2 predominantly tapped TR-related retrieval processes. All four control groups performed at ceiling. Three Greek-speaking PWAs, one Russian-speaking PWA, three Italian-speaking PWAs and two English-speaking PWAs showed between-task dissociations. A double dissociation emerged, as some Greek-, Russian- and English-speaking PWAs performed better on SCT 1 than on SCT 2, whereas other Greek- and Italian-speaking PWAs performed worse on SCT 1 than on SCT 2. It will be shown that the experimental design employed here has the potential to disentangle TR-related encoding deficits from TR-related retrieval deficits, as both PWAs with selective TR-related encoding deficits and PWAs with selective TR-related retrieval deficits were identified.
Personality Disorders and Traits of ABC Clusters in Fibromyalgia
Authors: Romanov Dmitry V. , Nasonova Tatiana I. , Isaikin Aleksey I. , Filileeva Olga V. , Sheyanov Andrey M. , Iuzbashian Polina G. , Voronova Evgenia I. , Parfenov Vladimir A.
Published: October 2023

Background: Evidence suggests that there is substantial comorbidity between fibromyalgia and Axis II pathology (i.e., personality disorders - PDs). The aim of the current study was to find out the exact cluster (A, B, C) PDs or traits that are more prominent in FM and may be predictors of FM diagnosis. Methods: Data from 86 subjects (53 with FM and 33 controls without FM) was analyzed in an observational, cross-sectional, comparative study. The assessment of categorical PDs and traits was performed independently with the Structured Clinical Interview for Personality Disorders (SCID-II). Binary logistic regression was used to determine FM predictors among PDs traits. Results. Compared with controls, FM patients had higher rate of PDs diagnoses (56.7 vs 18.2%, P<.001). However, the rate was significantly higher only for borderline PD diagnosis (28.3% vs 6.1% P<.05). The binary logistic regression analysis showed that schizotypal and schizoid (cluster A), borderline (cluster B), and dependent (cluster C) personality traits may be significant predictors of fibromyalgia (Nagelkerke R2 = 0.415). Conclusions: Our results may reflect association of FM with personality traits of all three PD clusters: A (eccentric), B (dramatic), C (anxious). However, the most consistent evidence seems to be for borderline PD.
The Proinflammatory Effects of 25-Hydroxyvitamin D3 in New-Onset Type 2 Diabetes Mellitus and Prediabetes
Authors: Fenercioglu Aysen Kutan , Gonen Mustafa Sait , Uzun Hafize , Sipahioglu Nurver Turfaner , Can Gunay , Tas Ebru , Kara Zehra , Ozkaya Hande Mefkure , Atukeren Pinar
Published: October 2023

In this study, we aimed to reveal the proinflammatory effects of serum 25-hydroxyvitamin D3 (Vit D) deficiency and insufficiency in new-onset type 2 diabetes mellitus (T2DM) and prediabe-tes. We recruited 84 prediabetes patients, 94 new-onset T2DM patients and 113 healthy partici-pants. Levels of C-reactive protein (CRP), fibrinogen, ferritin, interleukin-1β (IL-1β), interleu-kin-6 (IL-6), interleukin-8 (IL-8), tumour necrosis factor-α (TNF-α), nuclear factor kappa-B (NF-κB) and mitogen-activated protein kinase (MAPK) were measured in the serum of the par-ticipants. The ANOVA Bonferonni and Kruskal Wallis Dunn tests were used for the comparison of the inflammation markers and vitamin D levels between the groups. Upon covariance analy-sis with age, gender and BMI; Vit D levels of T2DM group were found to be significantly lower (p<0.003). Proinflammatory markers and CRP were found to be significantly higher in predia-betic and diabetic subjects. In the prediabetes group, IL-1β, IL-6, IL-8, TNF-α and MAPK were significantly higher in those with Vit D insufficiency and deficiency groups. In T2DM group, IL-1β, IL-6, IL-8, TNF-α, NF-κB, MAPK and CRP were significantly higher in those with Vit D insufficiency and deficiency. Our study emphasizes the proinflammatory effects of Vit D on the initiation of inflammation in both prediabetes and diabetes mellitus.
Embeddings of Graphs. Tessellate and Decussate Structures.
Authors: O'Keeffe Michael , Treacy Michael Matthew John
Published: October 2023

We address the problem of finding a unique graph embedding that best describes a graph's "topology". This issue is of particular interest in the chemistry of materials. Graphs that admit a tiling in 3-dimensional Euclidean space are termed tessellate, those that do not decussate. We give examples of decussate and tessellate graphs that are finite and 3-periodic. We conjecture that a graph has at most one tessellate embedding. We give reasons for considering this the default "topology" of periodic graphs.
A Rare Case of Isolated Hepatocellular Carcinoma Metastasis in Left Mandible in a Patient with Hepatitis C Virus Liver Cirrhosis Diagnosed after the onset of COVID 19 Infection
Authors: Mašulović Dragan , Igić Aleksa , Filipović Aleksandar , Zakošek Miloš , Bulatović Dušan , Mijović Ksenija , Micev Marjan , Galun Danijel
Published: October 2023

Liver is the sixth most common site of primary malignant tumors, and the third leading cause of cancer death worldwide. Hepatocellular carcinoma is the most common primary liver malignancy and lungs, abdominal lymph nodes and adrenal glands are the most common sites of its metastasis. We present a rare case of an isolated metastasis of a hepatocellular carcinoma in the left mandibular ramus, with regards to its clinical and radiological presentation and with regards to possible routes of the metastatic spread.
Unpredictable Metastasis in the Head and Neck Region: a Diagnostic Immunohistochemical Challenge
Authors: Closca Raluca-Maria , Nicoara Adrian , Rakitovan Marina , Mot Ion Cristian , Baderca Flavia
Published: October 2023

The metastatic disease is a complex and sequential process that involves the migration of tumor cells from the primary site to distant areas. This metastatic pathway is not always predictable. Therefore, this paper presents three rare cases of unusual metastases, due to their primary site: two metastases of a clear cell renal cell carcinoma, one gingival and one nasal, as well as a mandibular metastasis of a hepatocellular carcinoma. In all cases, an incisional biopsy was performed in order to sign out the diagnosis. After microscopical examination of morphological Hematoxylin and Eosin stained slides, for all cases, immunohistochemical reactions were performed to support the primary tumor site. Two cases had a previous histopathological diagnosis of a primary tumor, while for the third case, the metastatic lesion represented the first manifestation of the neoplastic disease, with an unfavorable prognosis.
Assessment of Bottom-Up Satellite Precipitation Products on River Streamflow Estimations in the Peruvian Pacific Drainage
Authors: Qquenta Jonathan , Rau Pedro , Bourrel Luc , Frappart Frédéric , Lavado-Casimiro Waldo
Published: October 2023

In regions with limited precipitation information like Peru, many studies rely on precipitation data derived from satellite products (SPPs) and reanalysis products. These products provide near-real-time information and offer global spatial coverage, making them attractive for various applications. However, it is essential to consider their uncertainties when conducting hydrological simulations, especially in a key region like the Pacific drainage (Pd), where 56% of Peruvian population resides (including the capital Lima).
This study evaluates the performance of three precipitation products: Reanalysis, ERA5-Land (top down approach), and two SPPs: GPM+SM2RAIN and SM2RAIN-ASCAT (bottom-up approaches). Hydrological modeling was conducted on 30 basins distributed across the Pd, which were grouped into five regions (I-V, ordered from south to north). The results showed that SM2RAIN-ASCAT performed well in regions I-III-IV, ERA5-Land in region II, and GPM+SM2RAIN in region V. The hydrological model GR4J was tested, and better efficiency criteria were obtained with SM2RAIN-ASCAT and GPM+SM2RAIN when comparing simulated versus observed streamflows. The hydrological modeling with SM2RAIN-ASCAT and GPM+SM2RAIN demonstrated satisfactory efficiency metrics (KGE > 0.75; NSE > 0.65). Additionally, ten hydrological signatures were quantified to assess the variability of simulated streamflows in each basin, with metrics such as Mean Flow (Q mean), 5th Quantile Flow (Q5), and 95th Quantile Flow (Q95) showing overall better performance.
Finally, the results of this study demonstrate the reliability of using bottom-up satellite products in Pd basins.
Effect of Magnesium and Biostimulant Fertilization on the Consumption Value and Safety of Potato Tubers after Long-Term Storage
Authors: Pobereżny Jarosław , Retmańska Katarzyna , Wszelaczyńska Elżbieta , Nogalska Anna
Published: October 2023

: The primary use of the potato is direct consumption. The classification of potatoes into consumption type is made on the basis of consumption evaluation of hydrothermally treated tubers. Nutrient deficiency in the soil, including Mg, contributes to the inhibition of potato growth and development and negatively affects the cooking characteristics of the tubers. Magnesium and biostimulants are responsible for plant nitrogen management. Thus, it is necessary to control the content of harmful nitrates and toxic nitrites in tubers. In potato production, it is also important to maintain appropriate conditions during storage. The purpose of this study was to determine the effect of mineral fertilization with magnesium and a biostimulant preparation during cultivation of edible potato and long-term storage on the traits determining utility-consumption type and the content of harmful nitrogen compounds in tubers. The study was conducted using the early potato variety Satina. In a three-year (2015-2017) three-factor experiment: evaluation date (immediately after harvest and after six months of storage), soil fertilization with mineral magnesium (0, 30, 60, 90 kg MgO ha-1), application of an amino acid biostimulant (0, 1.5, 3.0 l ha-1), five consumption traits of tubers after cooking determining the utility-consumption type of potato were determined. In addition, the consumer safety of the potato was determined based on the nitrate and nitrite content of the tubers. The tendency to overcook tubers significantly depended on all the factors used during potato cultivation. In contrast, the texture and structure of tuber flesh after cooking depended only on mineral fertilization with magnesium. The flesh of the tubers after cooking was most tender (1.0 pt) and firm (1.4 pt) after the application of 60 and 90 kg MgO ha-1, respectively. The moisture level of the flesh after cooking was significantly influenced by the interaction of magnesium fertilization with the biostimulant preparation. The factors of the experiment did not modify the utility-consumption type (B/A), while there was a change in the type in relation to that specified by the grower - general utility (B). The applied cultivation technology and long-term storage did not deteriorate the consumer safety of tubers (<200 mg kg-1) in terms of NO3 (max. 112.1 mg kg-1) and NO2 (max. 1.08 mg kg-1) contents. Organoleptic traits: mealiness, moisture and flesh structure were significantly positively related to nitrate and nitrite content of tubers immediately after harvesting and to nitrite concentration after long-term storage.
Environmental Enrichment in Cancer: A Possible Tool to Combat Tumor Development: A Systematic Review
Authors: Fernandes Matheus Santos , Lacerda Tiago Ramos , Fidelis Débora Eduarda da Silva , Santos Gabriela Carvalho Jurema , Filgueira Tayrine Ordonio , De Souza Raphael Fabrício , Lagranha Claúdia Jacques , Lira Fábio Santos , Castoldi Angela , Souto Fabricio Oliveira
Published: October 2023

Aims: This systematic review aims to evaluate the influence of Environmental Enrichment (EE) on oncological factors in experimental studies involving various types of cancer models.
Methods: A comprehensive search was conducted in three databases: PubMed (161 articles), Embase (335 articles), and Scopus (274 articles). Eligibility criteria were applied based on the PICOS strategy to minimize bias. Two independent researchers performed the searches, with a third participant resolving any discrepancies. The selected articles were analyzed, and data regarding sample characteristics and EE protocols were extracted. The outcomes focused solely on cancer and tumor-related parameters, including cancer type, description of the cancer model, angiogenesis, tumor occurrence, volume, weight, mice with tumors, and tumor inhibition rate.
Key-findings: A total of 770 articles were identified across the three databases, with 12 studies meeting the inclusion criteria for this systematic review. The findings demonstrated that different EE protocols were effective in significantly reducing various aspects of tumor growth and development, such as angiogenesis, volume, weight, and the number of mice with tumors. Furthermore, EE enhanced the rate of tumor inhibition in mouse cancer models.
Findings: This systematic review highlights the significant impact of EE protocols on multiple parameters associated with tumor growth and development, including angiogenesis, occurrence, volume, weight, and tumor incidence. Moreover, EE demonstrated the potential to increase the rate of tumor inhibition. These findings underscore the importance of EE as a valuable tool in the management of cancer.
Locus of Control and Self-Directed Learning Readiness of Nursing Students During the COVID-19 Pandemic: A Cross-Sectional Study from Saudi Arabia
Authors: Alkorashy Hanan A. , Alotaibi Hanan A.
Published: October 2023

Background: Coronavirus disease (COVID-19) has caused one of the worst global pandemics in recent decades. It has disrupted education systems worldwide, leading to a forced shift from traditional face-to-face to blended or fully distanced learning, requiring a higher level of student readiness for self-directed learning (SDL) and a more internal locus of control (LOC). Objective: This study explored the relationship between locus of control and level of readiness for SDL among Saudi nursing students and whether the COVID-19 pandemic has impacted this relationship. Methods: a cross-sectional correlational descriptive study was conducted to survey 277 Saudi nursing students enrolled in the bachelor program in one of the reputable universities in Saudi Arabia. An E-questionnaire containing two scales, the Self-Directed Learning Readiness Scale for Nursing Education, and the Locus of Control Scale, was used to collect data in addition to the selected participants’ characteristics. Results: Nursing students had a moderate-to-low level of readiness for SDL (mean = 144.0), and the majority had an external LOC. There was a significant association between locus of control and level of readiness for self-directed learning (r = 0.19*, p = 0.001), and the internal locus of control was more significantly associated with self-directed learning (r = 0.22*, p = 0.0001) than with external locus of control. Conclusion: The study findings indicate a propensity of respondents towards an external locus of control, whereas the majority of the respondents reported low to moderate levels of readiness across all dimensions of self-directed learning. This study was not registered.
Study of emphysematous changes in the population of Moscow using automated evaluation of radiological examinations.
Authors:   Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Vasilev Y.A. , Goncharova I.V. ,   Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Vladzymyrskyy A.V. ,   Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Arzamasov K.M. ,   Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Pestrenin L.D. ,   Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Published: October 2023

Background. Emphysema, commonly seen in patients with chronic obstructive pulmonary disease (COPD), worsens the course of chronic cardiovascular and endocrine diseases and is also associated with an increased risk of lung cancer. Although the evaluation of COPD incidence is applied systematically, the prevalence of emphysema is often not known. One of the ways to offset that is automated analysis of chest CT scans using artificial intelligence technologies. Goal. To study the prevalence of emphysema in the population of Moscow using automated analysis of radiological examinations. Methods. The results of the chest CT scan of 116,216 patients were analyzed. All studies were performed between October 2022 and June 2023 in Moscow medical facilities. The Emphysema-IRA AI service (Intelligent Radiology Assistance Laboratories (AIRA Labs) LLC) used an automated mode to determine the presence of emphysematous changes in the lungs (binary classification – yes/no) and the percentage of emphysematous lesions in both lungs and each lung separately. Results. The prevalence of pulmonary emphysema among the Moscow population was 0.614 per 1,000 people; the prevalence of clinically significant emphysema was 0.173 per 1,000 people. The majority of individuals presented with either pulmonary or clinically significant emphysema in CT belong to the elderly group (47.0% and 55.0%, respectively); the proportion of young people is also significant (9.0% and 5.0%). Men of all age groups have a significantly higher chance to get diagnosed with emphysema which suggests a higher incidence compared to the female population (Chi-square = 1000.0; p<0.001). Regardless of gender, a 5-year increase in age elevates the likelihood of both emphysema and clinically significant emphysema by 1.1 times. Conclusions. Automated detection of signs of pulmonary emphysema on CT allows for a quick, population-wide, and objective assessment of the COPD prevalence. Thanks to the development of AI-based medical software, it has become possible to develop and implement ground-breaking digital technologies for healthcare management and public health studies.
Digital transformation in primary health care and data-driven management.
Authors: Tyurganov A.G. , Khanov A.M.
Published: October 2023

In the contemporary healthcare context, there exists a necessity to optimize the organization and management of patient diagnosis, routing, and treatment, especially within the primary care sector. Within this scope, digital transformation assumes a pivotal role, offering novel avenues for enhancing the quality of medical assistance. Research Objective: This study aims to identify the fundamental issues pertaining to the organization and management of patient diagnosis, routing, and treatment within the primary care sector. Furthermore, the study seeks to formulate recommendations for addressing these challenges through the avenue of digital transformation. Materials and methods. The study was conducted through the utilization of comparative analysis employing synthesis, analysis, modeling, and specialization methodologies. Data were acquired through a specially developed questionnaire encompassing inquiries regarding healthcare process organization and management. Discussion and results. The outcomes of the investigation elucidate notable disparities between the organization and management of healthcare processes within the primary care sector and the inpatient setting. Notably, the application of digital technologies is underscored for its capacity to enhance patient-physician communication, reduce transactional overheads, and facilitate the effective collection and analysis of health-related data. Conclusion. The significance of digital transformation is underscored in enhancing patient satisfaction with medical care, optimizing processes, and elevating the quality of medical assistance within the primary care domain.
La lógica de la multiplicidad en Kafka y Cunqueiro: Das Schloss y Un hombre que se parecía a Orestes
Authors: Mariño Mexuto Marta
Published: October 2023

Das Schloss (1926) y Un hombre que se parecía a Orestes (1968) son dos novelas muy alejadas cronológica y temáticamente que no parecen mostrar ninguna similitud. Sin embargo, en ambas obras se aprecia un rasgo común que es fundamental para la comprensión de Kafka y Cunqueiro: se presenta una variedad de posibilidades o versiones de un mismo acontecimiento de forma no excluyente. Se configura así un mundo regido por una particular lógica, aunque el resultado final sea muy distinto en cada caso.
La institución judicial contra la creación poética: el proceso a Les fleurs du mal
Authors: García Calderón Ángeles , Aguilar Camacho María del Carmen
Published: October 2023

Les fleurs du mal (Las flores del mal), colección de poemas que inician la poesía moderna, fue censurada por Napoleón III, alegando que ultrajaban la moralidad pública y religiosa. Ambos, la acusación de M. Pinard y el alegato de Me Gustave Chaix d’Est-Ange, se formularon en versículos seleccionados para tal fin. Este artículo se centra en el proceso judicial cuyo fallo ordenó el pago de una multa al poeta y la retirada de seis poemas de la colección.
RESEÑA: Trabajos de investigación
Authors: He Dongxu
Published: October 2023

Reseña de trabajos de tesis doctorales realizada por Dongxu He.
Und Morgen die ganze Welt: Gewaltmanifestation als psychologische Antwort
Authors: Hirte Ricarda
Published: October 2023

Der Film Und Morgen die ganze Welt steht im Mittelpunkt des Beitrags, um die zunehmende Gewaltbereitschaft der Hauptfigur Luisa mit Hilfe der Psychologie eingehender zu betrachten. Neben Freuds Triebtheorie wird vor allem auf die Arbeit des forensischen Psychiaters Kröber eingegangen, der davon ausgeht, dass die Gewalt ein Teil der menschlichen Natur ist. So entwickelt sich der freudianische Todestrieb in einen Destruktionstrieb, der sich vom Ich lossagt und sich nach Außen hin manifestiert, wobei zu berücksichtigen ist, dass Gewalt und Destruktion immer an eine kulturelle Komponente gebunden ist. Anhand des psychischen Triebs kann man die Gewaltentwicklung der Filmheldin Luisa erklären, wobei als letzte psychische Instanz, die Moral, die Gewalt eindämmt oder ihr freien Lauf lässt.
Análisis y traducción del género policiaco y de su terminología jurídica a través de la novela "Un parfum de poison"
Authors: Sánchez Gutiérrez Bárbara
Published: October 2023

El presente trabajo consiste en la observación del comportamiento de los términos jurídicos en el género policiaco concretamente, a través de la traducción al español de la novela Un parfum de poison. Para ello, por un lado se analiza y se justifica la traducción de dichos términos al no encontrarse en un contexto estrictamente jurídico, por otro se expone la historia del género policiaco francés, español e hispanoamericano para conocer el funcionamiento de este género al ser relativamente nuevo. Asimismo, se enuncia cuál puede ser la mejor técnica de traducción de este género. Por último, dado el argumento de la obra, se exponen no solo los sistemas jurídicos de la cultura original y la cultura meta, sino también el anglosajón ya que este pertenece a un ordenamiento jurídico diferente al de dichas culturas.
Sentiments Analysis for intelligent customer service Dialogue Using Hybrid Word Embedding and Stacking Ensemble
Authors: duan chen , Zhengwei Huang , Jintao Min , Khanal Ribesh
Published: October 2023

With the development of e-commerce, the national e-commerce transaction volume sprung up. An increasing number of customers have made it a habit to contact online customer service when they run into difficulties while shopping online. These conversation texts include a large number of emotional words and tone particles, which can intuitively reflect customers' attitudes toward any situation, product, or service. The intelligent customer service conversation texts have the characteristics of serious colloquialism, high diversity of words, and short text length. Traditional sentiment analysis algorithms are not suitable for dialogue information. Besides, coarse-grained sentiment analysis could not fully display the text information of users in the dialogue, resulting in poor performance of sentiment classification prediction. In this paper, we propose a hybrid word embedding method based on Gaussian distribution to leverage the emotional syntactic and semantic richness of the two distributed word representations. Furthermore, this study utilizes a stacked ensemble method by combining the outputs obtained from three deep learning models (i.e., CNN, LSTM, and GRU) for simultaneously predicting coarse-grained and fine-grained sentiment analysis in the customer service conversation domain. The results show that hybrid word embedding (HWE) can assist us in comprehending our word representations in context more effectively. In comparison to the current state-of-the-art models, our proposed ensemble model significantly enhances sentiment classification performance.
Electrical facies of the Asmari Formation in the Mansouri oilfield, an application of multi-resolution graph-based and artificial neural network clustering methods
Authors: Eftekhari Seyedeh Hajar , Memariani Mahmoud , Maleki Zahra , Aleali Mohsen , Kianoush Pooria
Published: October 2023

Electrofacies analysis conducted the distribution effects throughout the reservoir despite the difficulty of characterizing stratigraphic relationships. Clustering methods quantitatively define the reservoir zone from non-reservoir considering electrofacies. Asmari Formation is the most significant reservoir of the Mansouri oilfield in SW Iran, generally composed of carbonate and sandstone layers. The stratigraphical study is determined by employing 250 core samples from one exploratory well in the studied field. Five zones with the best reservoir quality in zones 3 and 5 containing sandstone/shale are determined. Moreover, multi-resolution graph-based and artificial neural network clustering involving six logs are employed. Utilizing Geolog software, an optimal model with eight clusters with better rock separation is obtained. Eventually, five electrofacies with different lithological compositions and reservoir conditions are identified and based on lithofacies describing thin sections, sandstone, and shale in zones 3 and 5 show high reservoir quality. According to the depth related to these zones, most of the facies that exist in these depths include sandstone and dolomite facies, and this is affected by the two factors of the primary sedimentary texture and the effect of the diagenesis process on them. Results can compared to the clustering zone determination in other nearby sandstone reservoirs without cores.
Optimization of Cutting Parameter in Turning of Super Duplex Stainless Steel -SDSS 2507 with textured tools under MQL conditions
Authors: Thimmaiaha Jagadeesha , Chaturvedi Avinash Kumar
Published: October 2023

Super-duplex stainless steel (SDSS) 2507 is a type of material known for its outstanding mechanical properties and superior corrosion resistance due to its complex microstructure and the presence of various alloying elements. However, due to these characteristics, machining this material can be challenging. To address this issue, manufacturing industries have been exploring innovative ways to use lubricants during machining while considering their environmental impact. Manufacturing industries have been making efforts to move away from using large amounts of lubricants and instead adopt minimum quantity lubrication techniques. Meanwhile, the advantages of using textured surfaces in improving tribological properties have also been recognized. A lot of research has been done to enhance the performance and durability of components by modifying their surface topography. Recently, textured surfaces have also been applied in cutting tools. The use of micro dimples or linear grooves on the rake or flank face of the tool has been shown to reduce cutting forces, friction coefficients, and cutting temperatures. Consequently, this has led to improvements in machining output parameters and increased tool longevity. This study proposes a new sustainable machining approach by combining two techniques: the use of surface textured tools and minimum quantity lubrication (MQL). Two types of cutting tools were used in the experiment: a surface textured tool with circular pit holes, and a hybrid texture tool with a combination of circular pit holes and linear grooves, both under MQL. The experiments are planned based on fractional factorial design and measured cutting forces and tool flank wear were compared with the predicted forces in order to validate the feasibility of the proposed design. The contribution of each process parameter was determined through the analysis of variance (ANOVA) to assess the percentage impact of each parameter. The cumulative effect of both circular and perpendicular textures provides the hybrid texture with superior debris entrapment capability while acting as a chip breaker which reduces the adhesion between the chip and the insert, resulting in better surface finish and wear resistance and hybrid texture tool significantly reduced the tool flank wear and cutting force.
Unlock the full potential of ordinary Portland cement with hydration control additive enabling low-carbon building material
Authors: Dengler Joachim , Li Xuerun , Grassl Harald , Hesse Christoph
Published: October 2023

Ordinary Portland cement (OPC) is the core ingredient of many construction materials. In 2022, 4.1 billion tons were used worldwide, contributing to approximately 8% of anthropogenic CO2 emissions (~3 Gt/year). There are alternatives to OPC such as aluminate cement and geopolymers, but due to the cost and availability of raw materials, their application is limited2. Thus, the use of OPC-based construction materials is expected to remain significant. Nevertheless, the complete strength-generating capacity of OPC remains unrealized due to the restricted conversion of aluminates to ettringite, caused by conventional hydration kinetics. In this study, we employ a hydration control additive that selectively modifies the hydration kinetics, thereby facilitating enhanced dissolution of aluminates in OPC, which promotes the formation of ettringite at a specific desired time. The increased ettringite content improves packing of the cement, resulting in ~50% higher specific strength thus enables cement reduction. The increased efficiency of strength development of OPC reduces the carbon footprint by at least ~30%. The use of this additive can be combined with methods such as reducing the amount of water and/or using supplementary cementitious materials (SCMs) to prepare building materials with significantly fewer CO2 emissions than those from conventional OPC.
Uso De Fitoreguladores E Fitoprotetores Na Produção De Mudas De Melancia (Citrullus Lanatus) Em Água Biosalina.
Authors: Silva José Eduardo Santos Barboza da , Guirra Keylan Silva , GUIRRA BRUNO SILVA , Neto Francisco Assis Nogueira , Dantas Barbara França , Leite Moadir de Sousa
Published: October 2023

The use of phytoregulators and phytoprotectants in seed treatment may promote greater tolerance to saline stress. Thus, our objective was to evaluate the effects of seed treatment with phytoregulators and phytoprotectants on the emergence, establishment, development, and quality of watermelon cultivar Crimson Sweet seedlings in biosaline water (BW). The study design was completely randomized, with a 2 × 7 factorial scheme, the first factor consisting of two types of water (drinking water and biosaline water), and the second factor comprising three phytoregulators (salicylic acid, putrescina and gibberellic acid), three phytoprotectors (naphthalic anhydride, thiamethoxam and acibenzolar-S-methyl), in addition to the control treatment. The seedlings were evaluated at 14 days after sowing. Fresh vegetable material was collected to determine the levels of sugars and proteins in the tissues. The salinity of the water affected the development of watermelon seedlings, but it was observed that some evaluated products allow a reduction of the damages caused by the stress. Seedlings were more vigorous when treated with thiamethoxam, even when submitted to biosaline water, compared to control in normal water. Thus, seed treatment with thiamethoxam provides a higher quality of watermelon cultivar Crimson Sweet seedlings in biosaline water.
The Evolution and Future of Research on Nature-based Solutions to Address Societal Challenges
Authors: Dunlop Thomas , Khojasteh Danial , Cohen-Shacham Emmanuelle , Glamore William , Haghani Milad , Bosch Matilda van den , Rizzi Daniela , Greve Peter , Felder Stefan
Published: October 2023

Nature-based Solutions (NbS) are widely recognised for their potential to prevent the ongoing biodiversity and climate crises, and to a lesser extent, address a broader range of societal issues. However, this relationship between nature and society is becoming more important as available food and water resources, income, and health, are increasingly impacted by changes to the environment. In this study, a systematic analysis, utilising the seven major societal challenges addressed by NbS according to IUCN, was undertaken to identify the primary themes of the NbS research landscape from 1990–2021 and evaluate how these themes and the societal challenges that they target, evolved over time, and where. Our findings highlight the under-representation of four societal challenges across the NbS research landscape, namely economic and social development, human health, food security, and water security. We propose six research pathways to advance the scientific basis of NbS in these four societal challenges, and present opportunities for future NbS research programs to prioritise the needs of society, the environment, and the economy.
Arm circumference is positively correlated with total femur bone mineral density among adults aged 50 years old and above: The NHANES 2013-2020
Authors: Chen Yuanyuan , Xu Jing
Published: October 2023

Background:The arm circumference (AC) has been used as an important tool to access the bone mineral density (BMD) of the postmenopausal females. However, the relationship between the AC and total femur BMD remains unclear in American adults. This study aims to explore the relationship between AC and total femur BMD in American adults.Methods:This rigorous study focused on adults aged 50 years old or above, using data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2013 and 2020. The study examined the relationship between AC and total femur BMD in a population-based sample. In order to analyze this relationship, weighted multivariate linear regression and smoothed curve fitting methods were adopted. Additionally, this study used a two-part linear regression model to identify threshold effects. Subgroup analysis and interaction tests were also conducted.Results:Multivariate linear regression analysis revealed a significant positive correlation between AC and total femur BMD in 5536 US adults aged 50-80 years old [β= 0.013, 95% CI: (0.009, 0.016)]. Positive correlations were consistent for all subcategories (including gender, diabetes status, race and physical activity subgroups) except for age and BMI. Furthermore, a non-linear relationship and saturation effect between AC and total femur BMD were identified, with an inverted L shaped curve and an inflection point at 35.4cm.Conclusions:Our study shows that there is a significant positive correlation and saturation effect between AC and total femur BMD in American adults.
Longitudinal dynamic single-cell mass cytometry analysis of peripheral blood mononuclear cells in COVID-19 patients within 6 months after viral RNA clearance
Authors: Zhou diwenxin , Zhao Shuai , He Keting , Liu Qiuhong , Zhang Fen , Pu Zhangya , Xiao Lanlan , Zhang Lingjian , Chen Shangci , Qian Xiaohan , Wu Xiaoxin , Shen Yangfan , Yu Ling , Zhang Huafen , Jin Jiandi , Xu Min , Wang Xiaoyan , Zhu Danhua , Xie Zhongyang , Xu Xiaowei
Published: October 2023

This study investigates the longitudinal dynamic changes in immune cells in COVID-19 patients over an extended period after recovery, as well as the interplay between immune cells and antibodies. Leveraging single-cell mass spectrometry, we selected six COVID-19 patients and four healthy controls, dissecting the evolving landscape within six months post-viral RNA clearance, alongside the levels of anti-spike protein antibodies. The T cell immunophenotype ascertained via single-cell mass spectrometry underwent validation through flow cytometry in 37 samples. Our findings illuminate that CD8+ T cells, gamma-delta (gd) T cells, and NK cells witnessed an increase, in contrast to the reduction observed in monocytes, B cells, and double-negative T (DNT) cells over time. The proportion of monocytes remained significantly elevated in COVID-19 patients compared to controls even after six-month. Subpopulation-wise, an upsurge manifested within various T effector memory subsets, CD45RA+ T effector memory, gdT, and NK cells, whereas declines marked the populations of DNT, naive and memory B cells, and classical as well as non-classical monocytes. Noteworthy associations surfaced between DNT, gdT, CD4+ T, NK cells, and the anti-S antibody titer. This study reveals the changes in peripheral blood mononuclear cells of COVID-19 patients within 6 months after viral RNA clearance and sheds light on the interactions between immune cells and antibodies. The findings from this research contribute to a better understanding of immune transformations during the recovery from COVID-19 and offer guidance for protective measures against reinfection in the context of viral variants.
Simulation-Based Assessments in Health Professional Education: A Scoping Review
Authors: Siavashpour Zahra , Bosak Somaieh , Sohrabi Somaye , Khoshgoftar Zohreh
Published: October 2023

Background The utilization of simulation in healthcare education has grown significantly in the last 20 years. Although typically used for training purposes, simulation is increasingly used for assessing technical skills needed in clinical practice. Despite its common use, there has been no investigation into the full potential of simulation in healthcare education. This study aims to explore the scope of simulation-based assessments in healthcare education. Methods Using the Joanna Briggs Institute’s scoping review methodology, we searched Ovid MEDLINE, Embase, Scopus, WOS, CINAHL, APA PsycINFO, and Embase databases and two well-known simulations in medical education, Clinical Simulation in Nursing and Simulation in Healthcare, from 2021 to 2023. We also checked the reference lists of review articles. We imported, deduplicated, and screened the search results in EndNote X20. We included 49 studies that met our criteria and analyzed them descriptively and narratively. Results We specified the target groups and applications for simulation-based assessment in healthcare professional education. We also identified challenges, advantages, and disadvantages, as well as the necessary conditions for conducting such assessments. Conclusions Simulation-based evaluation is beneficial for health education in evaluating competence and safety. Nevertheless, limitations such as high costs and low realism should be taken into account. Stakeholders and educators must study these concerns, establish standards for evaluation and sampling, and conduct planning and evaluation before using these methods.