bluuebunny/crossref_metadata_2025 huggingface dataset:
Could God Love Cruelty?
Authors: Callahan Laura Frances
Published: July 2021

One of the foremost objections to theological voluntarism is the contingency objection. If God’s will fixes moral facts, then what if God willed that agents engage in cruelty? I argue that even unrestricted theological voluntarists should accept some logical constraints on possible moral systems—hence, some limits on ways that God could have willed morality to be—and these logical constraints are sufficient to blunt the force of the contingency objection. One constraint I defend is a very weak accessibility requirement, related to (but less problematic than) existence internalism in metaethics. The theological voluntarist can maintain: Godcouldn’t have loved cruelty, and even though he could have willed behaviors we find abhorrent, he could only have done so in a world of deeply alien moral agents. We cannot confidently declare such a world unacceptable.
Evil: A History
Authors: Aijian J. L.
Published: July 2021

Evil: A History, edited by Andrew P. Chignell. Oxford University Press, 2019. Pp. xxiv + 499. $36.95 (paperback).
The Kingdom of God in the Church and the Experience of Human History
Authors: Appiah-Kubi Francis , KariKari Isaac Osei
Published: July 2021

Understanding the idea of the reign of God in the affairs of humans must not only be envisaged or experienced by the ecclesiastical setting or arena. The hope in the existence of God’s kingdom transcends the spiritual emphasis to the socio-cultural and politico-economic realms. This article looks at the penetrating effects of the Christian principles and ideals of God’s kingdom envisaged in the Church and the human historical experiences which as the mouthpiece of the coming kingdom of God represents its message to the wider human sociality. Are there any socio-cultural, economic and political implications of reechoing God’s active role in making the life of the people become meaningful and peaceful? The study concentrates on the Kingdom of God in its relationship with human history. It focuses on some theological thoughts from both catholic and protestant perspectives. It elucidates the significance of the Kingdom of God in the transformation of human history by first considering the Universal Kingdom of God, as a symbol of hope for humanity and examining critically the socio-political implication of the Kingdom in the proclamation of Jesus the Christ.

Keywords: Kingdom of God, Political theology, Historical Experience, Socio-political, Social transformation.
derecho a la salud en tiempos de pandemia
Authors: Álvarez Vita Juan
Published: July 2021

La pandemia del coronavirus o COVID-19 está poniendo a prueba a todas las declaraciones y tratados internacionales, a los derechos humanos y a la manera de actuar a la diplomacia.
Corte Internacional de Justicia: 75 años
Authors: Deustua Caravedo Alejandro
Published: July 2021

De acuerdo a sus orígenes, la Corte Internacional de Justicia ha priorizado la continuidad sobre el cambio aún en periodos de fuerte presión sistémica. Durante los 75 años de vigencia su limitaciones y problemas vinculados a la realidad de una jurisdicción no obligatoria, el fraccionamiento jurisdiccional o el error perceptivo de su autoridad (no se trata de una corte global ni de una corte suprema), la Corte ha sostenido el principio de la soberanía estatal en el acceso a la solución institucional de controversias aún en épocas de problemas transnacionales. Su efectividad y reconocimiento es acorde con la calidad de sus sentencias que provienen de la competencia y diversidad de sus jueces y con su status de principal órgano jurídico de la ONU. LA CIJ es un régimen de relaciones internacionales cuya influencia ha variado según la época y la cohesión corporativa del tribunal.
Rafael Roncagliolo en la Cancillería
Authors: Rojas Samanez Fernando
Published: July 2021

El fallecimiento de Rafael Roncagliolo ha generado amplio impacto en diferentes sectores e instituciones nacionales e internacionales, que lamentaron su desaparición y destacaron su extensa trayectoria política, social y académica, sobre todo en la búsqueda de consensos a favor de la democracia, la institucionalidad y la transparencia en la actividad política pública y privada. El acto realizado el jueves 14 de mayo, convocado por el Acuerdo Nacional y que encabezó el Presidente de la República, constituyó en mi opinión, un evento de homenaje público de la sociedad civil, sin precedentes. No hubo excesos, fue un acto sobrio y sentido que, en los días actuales en el país, adquirió mayor significado y que se puede condensar en algunas simples palabras: voluntad, diálogo, respeto, gobernabilidad, democracia, compromiso y que confluyeron en un objetivo: el Perú y sus ciudadanos.
The Planetary Ephemeris Program: Capability, Comparison, and Open Source Availability
Authors: Chandler John F. , Battat James B. R. , Murphy Thomas W. , Reardon Daniel , Reasenberg Robert D. , Shapiro Irwin I.
Published: July 2021

We describe for the first time in scientific literature the Planetary Ephemeris Program (PEP), an open-source general-purpose astrometric data-analysis program. We discuss, in particular, the implementation of pulsar timing analysis, which was recently upgraded in PEP to handle more options. This implementation was done independently of other pulsar programs, with minor exceptions that we discuss. We illustrate the implementation of this capability by comparing the postfit residuals from the analyses of time-of-arrival observations by both PEP and Tempo2. The comparison shows substantial agreement: 22 ns rms differences for 1065 pulse time-of-arrival measurements for the millisecond pulsar in a binary system, PSR J1909-3744 (pulse period 2.947108 ms; full width half maximum of pulse 43 μs), for epochs in the interval from 2002 December to 2011 February.
TOI-1634 b: An Ultra-short-period Keystone Planet Sitting inside the M-dwarf Radius Valley
Authors: Cloutier Ryan , Charbonneau David , Stassun Keivan G. , Murgas Felipe , Mortier Annelies , Massey Robert , Lissauer Jack J. , Latham David W. , Irwin Jonathan , Haywood Raphaëlle D. , Guerra Pere , Girardin Eric , Giacalone Steven A. , Bosch-Cabot Pau , Bieryla Allyson , Winn Joshua , Watson Christopher A. , Vanderspek Roland , Udry Stéphane , Tamura Motohide , Sozzetti Alessandro , Shporer Avi , Ségransan Damien , Seager Sara , Savel Arjun B. , Sasselov Dimitar , Rose Mark , Ricker George , Rice Ken , Quintana Elisa V. , Quinn Samuel N. , Piotto Giampaolo , Phillips David , Pepe Francesco , Pedani Marco , Parviainen Hannu , Palle Enric , Narita Norio , Molinari Emilio , Micela Giuseppina , McDermott Scott , Mayor Michel , Matson Rachel A. , Martinez Fiorenzano Aldo F. , Lovis Christophe , López-Morales Mercedes , Kusakabe Nobuhiko , Jensen Eric L. N. , Jenkins Jon M. , Huang Chelsea X. , Howell Steve B. , Harutyunyan Avet , Fűrész Gábor , Fukui Akihiko , Esquerdo Gilbert A. , Esparza-Borges Emma , Dumusque Xavier , Dressing Courtney D. , Fabrizio Luca Di , Collins Karen A. , Cameron Andrew Collier , Christiansen Jessie L. , Cecconi Massimo , Buchhave Lars A. , Boschin Walter , Andreuzzi Gloria
Published: July 2021

Studies of close-in planets orbiting M dwarfs have suggested that the M-dwarf radius valley may be well explained by distinct formation timescales between enveloped terrestrials and rocky planets that form at late times in a gas-depleted environment. This scenario is at odds with the picture that close-in rocky planets form with a primordial gaseous envelope that is subsequently stripped away by some thermally driven mass-loss process. These two physical scenarios make unique predictions of the rocky/enveloped transition’s dependence on orbital separation such that studying the compositions of planets within the M-dwarf radius valley may be able to establish the dominant physics. Here, we present the discovery of one such keystone planet: the ultra-short-period planet TOI-1634 b (P = 0.989 days,

F
=
121

F

⊕

,

r

p

=

1.790

−
0.081

+
0.080

R
⊕) orbiting a nearby M2 dwarf (K

s
 = 8.7, R

s
 = 0.450 R
⊙, M

s
 = 0.502 M
⊙) and whose size and orbital period sit within the M-dwarf radius valley. We confirm the TESS-discovered planet candidate using extensive ground-based follow-up campaigns, including a set of 32 precise radial velocity measurements from HARPS-N. We measure a planetary mass of

4.91

−
0.70

+
0.68

M
⊕, which makes TOI-1634 b inconsistent with an Earth-like composition at

5.9
σ

and thus requires either an extended gaseous envelope, a large volatile-rich layer, or a rocky composition that is not dominated by iron and silicates to explain its mass and radius. The discovery that the bulk composition of TOI-1634 b is inconsistent with that of Earth supports the gas-depleted formation mechanism to explain the emergence of the radius valley around M dwarfs with

M

s

≲
0.5

M
⊙.
Model-independent Estimation of H
0 and Ω
K
from Strongly Lensed Fast Radio Bursts
Authors: Zhao Shaoxin , Liu Bin , Li Zhengxiang , Gao He
Published: July 2021

Model-independent estimation of H
0 and Ω
K
can provide clues about the origin of the intractable Hubble constant tension and the current cosmic-curvature crisis. Strongly lensed fast radio bursts (FRBs) have been proposed as precision probes of the universe since the time delay ∼



(10 days) between images could be precisely measured due to short durations ∼


(
ms
)

of this kind of bright radio pulses. Here, on the basis of the distance sum rule, we investigate the capacity of model-independently estimating these two parameters from time-delay distances of strongly lensed FRBs and luminosity distances of the upcoming Wide Field InfraRed Survey Telescope (WFIRST) type Ia supernovae observations. Considering the expected FRB detection rate of upcoming facilities, we find that H
0 could be determined to a ∼1% precision and Ω
K
could be constrained to ∼0.1 simultaneously from 10 lensed FRBs. These estimations, which are independent of the energy contents of the universe and validity of Einstein’s equation on cosmological scales, will be complementary to popular probes and of great importance for clarifying the current crises of cosmology.
Fluvial Features on Titan and Earth: Lessons from Planform Images in Low-resolution SAR
Authors: Miller J. W. , Birch S. P. D. , Hayes A. G. , Malaska M. J. , Lopes R. M. C. , Schoenfeld A. M. , Corlies P. M. , Burr D. M. , Farr T. G. , Perron JT
Published: July 2021

Cassini Synthetic Aperture Radar (SAR) images of Titan’s surface revealed river networks strikingly similar to those on Earth. However, Cassini SAR has low spatial resolution and image quality compared to data used to map channels on Earth, so traditional methods for characterizing river networks might not yield accurate results on Titan. We mapped terrestrial analog networks with varying resolutions and image qualities to determine which geomorphologic metrics were invariant with scale or resolution. We found that branching angle and drainage density varied significantly with image resolution, and we therefore expect the actual drainage density of Titan’s channel networks to be significantly higher than the values calculated from Cassini data. Calculated network geometry did not change predictably with resolution and would therefore not be an ideal metric for interpreting Titan’s channel networks. The measured channel width, basin length and width, and drainage area all behaved predictably as resolution varied, leading us to conclude that these metrics could be applied to Cassini data. We then mapped all observable fluvial features on Titan—excluding those in the highly incised labyrinth terrains—visible in the Cassini data set. In our new maps, we observe differences in basin shapes between Titan’s polar and equatorial regions and dichotomies in the relative channel density between the northern and southern midlatitudes and poles of Titan: channels are concentrated at the poles and southern midlatitudes. These patterns may reflect differences in bedrock material and/or different climate histories.
The Geographic Distribution of Dense-phase O2 on Ganymede
Authors: Trumbo Samantha K. , Brown Michael E. , Adams Danica
Published: July 2021

Ground-based spectroscopy of Ganymede’s surface has revealed the surprising presence of dense-phase molecular oxygen (O2) via weak absorptions at visible wavelengths. To date, the state and stability of this O2 at the temperatures and pressures of Ganymede’s surface are not understood. Its spatial distribution in relation to albedo, expected temperatures, particle irradiation patterns, or composition may provide clues to these unknowns. We present spatially resolved observations of Ganymede’s surface O2 obtained with the Hubble Space Telescope and construct the first comprehensive map of its geography. In agreement with the limited spatially resolved data published previously, our map suggests that the condensed O2 is concentrated at the low to midlatitudes of the trailing hemisphere, a distribution that may reflect influences of Ganymede’s intrinsic magnetic field on the bombardment of its surface by Jovian magnetospheric particles. Overlapping regions from different observations within this data set also show evidence for moderate temporal variability in the surface O2, but we are unable to distinguish between potential causes with the available data.
Monilochaetes pteridophytophila (Australiascaceae, Glomerellales), a new fungus from tree fern
Authors: Zhang Jingyi , Phookamsak Rungtiwa , Mapook Ausana , Lu Yongzhong , Lv Menglan
Published: July 2021

During taxonomic and phylogenetic studies of fungi on pteridophytes in Thailand, Monilochaetes pteridophytophila sp. nov. was collected from the frond stalks of a tree fern (Alsophila costularis, Cyatheaceae). The new species is introduced, based on evidence from morphology and phylogenetic analyses of a concatenated dataset of LSU, ITS, SSU and RPB2 sequences.

Monilochaetes pteridophytophila differs from extant species of Monilochaetes in having darker conidiophores with fewer septae (1–4-septate). Monilochaetes pteridophytophila forms a distinct clade, basal from other species of Monilochaetes in Australiascaceae. A detailed description and illustrations of the new species are provided. We also provided a synopsis of accepted species of Monilochaetes.
How green the urban development units in Sofia are: Earth observation and population time series analysis
Authors: Sarafova Eugenia
Published: July 2021

Over the last decades, the pressure that people and their activities put on the environment has increased. Green areas in many cities are diminishing in size due to urbanization, which inevitably leads to a decrease in quality of life. This study uses remote sensing (RS) data for Sofia, Bulgaria, for a period of nearly four decades, analyzing the dynamics of NDVI of the urban development units (UDUs). Statistics for NDVI per were calculated for each UDU for eleven dates in the following years: 1987, 1990, 1992, 1993, 1996, 2000, 2001, 2002, 2011, 2015, and 2020.  An estimate was made of the amount of green vegetation per capita, similar to other coefficients used for population analysis. NDVI profiles for major urban parks showed differences for the studied period. Sentinel-2 data for 2020 was used for visualization of the current situation, in combination with detailed population data for all UDUs. The obtained data will help the decision-making process for the development of UDUs, while the methodology can be applied in any other city worldwide.
Two new species of the genus Camptoscaphiella from Yunnan, China (Araneae, Oonopidae)
Authors: Huang Ying , Bian Dongju , Tong Yanfeng , Li Shuqiang
Published: July 2021

Two new species of the genus Camptoscaphiella Caporiacco, 1934 are described from Yunnan, China, i.e., C. changxu Tong & Li, sp. nov. (♂♀) and C. linyejiei Tong & Li, sp. nov. (♂♀). Camptoscaphiella changxu Tong & Li, sp. nov. is characterized by the long, strongly-curved setae between male paturons, which is unknown in other oonopids and in any other spiders. Camptoscaphiella linyejiei Tong & Li, sp. nov. is the third blind species of this genus in the world. Morphological descriptions and photographic illustrations of the two new species are given.
Éternité et durée selon Spinoza
Authors: Ledesma Viteri Juan Manuel
Published: July 2021

Cet article interroge la construction de la philosophie de Gilles Deleuze à partir de son rapport à la pensée de Spinoza. En partant d’une remarque dans Différence et répétition au sujet de l’ontologie spinozienne, nous interrogeons à la fois le problème du temps et de l’éternité chez Spinoza et la genèse de l’ontologie deleuzienne de la différence dans la mesure où elle s’affirme comme héritière de l’affirmation spinozienne de l’univocité de l’être.
Déconfinés, mais pas isolés !
Authors: Guedj Jérôme
Published: July 2021

Entre mars et juillet 2020, Jérôme Guedj, conseiller départemental de l’Essonne, a conduit une mission relative à la lutte contre l’isolement des personnes âgées et fragiles en période de confinement, à la demande du ministre des Solidarités et de la Santé. Retour sur les conclusions principales de la mission et les évolutions en cours.
Mobi-Cité Seniors, la médiation sociale au service de la mobilité des personnes âgées
Authors: Lardin Clélia
Published: July 2021

Ne pouvant pas sortir facilement et ainsi accéder aux commerces et services du quotidien, de nombreuses personnes âgées se replient sur elles-mêmes. Depuis septembre 2012, en lien avec ses partenaires de la ville de Bron, la régie de quartier a développé un service de proximité pour lutter contre l’isolement des personnes âgées du territoire. « Mobi-Cité Seniors » est porté par une équipe de médiateurs en contrat d’adultes-relais, sous la responsabilité de la coordinatrice du pôle médiation, Clélia Lardin.
Accompagner le maintien à domicile : le rôle clé des bailleurs
Authors: Bahloul Siham , Deloche Xavier , Molina Cruz Séverine
Published: July 2021

Adaptation des logements, construction de résidences seniors, projets intergénérationnels, formation et sensibilisation des personnels… l’éventail des actions conduites par les bailleurs en faveur du maintien à domicile des personnes âgées est très large, comme en témoignent les expériences présentées par trois bailleurs : Montluçon Habitat, Lyon Métropole Habitat et GrandLyon Habitat.
Traduire politiquement le soulèvement de mai 2021 : les défis du mouvement national palestinien
Authors: Dot-Pouillard Nicolas
Published: July 2021

Dans les rapports de force inter-palestiniens, le Hamas est sorti renforcé du soulèvement de mai 2021 et de la guerre à Gaza. Le Fatah, quant à lui, est miné par des divisions internes. Il hésite entre un retour à l’Intifada et la seule défense de l’Autorité nationale palestinienne. Réforme de l’Organisation de libération de la Palestine (OLP), élections, renouvèlement du leadership palestinien, réconciliation inter-palestinienne : le mouvement national palestinien est à un tournant. Dans ce contexte, les divisions inter-palestiniennes priment toujours et le soulèvement de mai 2021 ne trouve pas encore de traduction politique.
Les alliances asymétriques : perception et gestion des risques relationnels
Authors: Mahamadou Zoubeyda
Published: July 2021

Cet article se propose d’explorer la question des risques relationnels perçus par les PME dans le cadre de leurs partenariats asymétriques ainsi que les modes de gestion y afférant. Dans cette perspective, une étude qualitative exploratoire de dix PME opérant dans l’industrie aéronautique française a été menée. Nos résultats démontrent l’existence d’une différence de perception des risques relationnels par les dirigeants des PME selon que l’on soit en phase de négociation ou en phase de conduite de l’accord. Il semblerait aussi qu’il n’existe pas de mode de gestion spécifique et privilégié des risques relationnels dans le cadre des alliances asymétriques. La combinaison de différents facteurs formels et informels est importante.
Quel(s) sociétariat(s) pour les groupes bancaires coopératifs en France ? Premiers résultats d’analyse d’un échantillon de jeunes sociétaires du Crédit Mutuel de Bretagne (CMB)
Authors: Le Foll Sébastien , Glémain Pascal , Cadiou Christian
Published: July 2021

Cet article interroge le modèle de la relation bancaire entre les banques de réseau coopératives et leur sociétariat. Dans un contexte socio-économique en pleine mutation, comment les sociétaires vivent-ils aujourd’hui la (les) relation(s) de proximité avec leurs caisses locales? Nos résultats, issus d’une étude menée auprès de 982 jeunes sociétaires du CMB, proposent une grille de lecture basée sur la complexité du vécu et des attentes du sociétariat vis-à-vis du concept de proximité.
La Blockchain, un outil innovant au service du financement des entreprises
Authors: Alfieri Elise , Burlacu Radu , Enjolras Geoffroy
Published: July 2021

Le financement des entreprises bénéficie de l’introduction de techniques et solutions innovantes fondées sur la technologie blockchain. Afin de les analyser, cet article propose un cadre théorique centré sur les risques : les mécanismes de marché, les asymétries d’information, l’opportunisme, les garanties juridiques et les risques opérationnels. A partir d’une analyse de la littérature, nous développons une typologie des modes de financement en nous appuyant sur deux dimensions : les moyens d’échange et les contrats. Une étude de quatre situations appuie cette classification et démontre le potentiel de la blockchain en dépit de l’apparition de nouveaux risques.
L’étude de la Tétranormalisation dans le secteur réglementé de l’expertise-comptable : le cas de l’intégration des normes qualité
Authors: Eve Arnaud , Sprimont Pierre-Antoine
Published: July 2021

Les organisations sont soumises à un foisonnement de normes qui implique de questionner leurs relations. Pour répondre au besoin d’études sur l’ingénierie normative dans les secteurs réglementés, cette recherche questionne les relations entre la Norme Professionnelle de Maîtrise de la Qualité, réglementaire et obligatoire dans la profession comptable, et la norme de management de la qualité ISO 9001 dans six cabinets d’expertise-comptable. Les résultats montrent que la Tétranormalisation peut être envisagée de façon favorable dans des organisations de l’expertise-comptable. Le besoin de management des structures étudiées explique le recours à la norme ISO 9001 en association avec la Norme Professionnelle de Maîtrise de la Qualité.
Le management du capital humain dans le cadre d’une approche de développement organisationnel : étude de cas dans le secteur médico-social
Authors: Goujon Belghit Anne , Cuénoud Thibault , Bretonès Daniel , Cherrad Othmane
Published: July 2021

Le management du capital humain ouvre une nouvelle piste pour améliorer la performance globale des organisations dans la mesure où la démarche est multipartite. L’étude de cas « Solincité » offre un contexte d’analyse intéressant pour plusieurs raisons. Tout d’abord, il s’agit du secteur social et médico-social, aux contraintes et règles de fonctionnement bien spécifiques. Ensuite, le cas retrace le parcours d’une intégration de deux établissements pour devenir une seule organisation. Finalement un modèle intégrateur est proposé, soulignant les mises en relation inter-capital humain et les risques associés à ces dynamiques de changement dans une approche de développement organisationnel.
Predefined-time vector-polynomial-based synchronization among a group of chaotic systems and its application in secure information transmission
Authors: Li Qiaoping ,   Zhengzhou University of Aeronautics, Zhengzhou 450015, China, Liu Sanyang ,   School of Mathematics and Statistics, Xidian University, Xi'an 710071, China
Published: July 2021

This article aims to improve the security and timeliness of chaotic synchronization scheme in chaotic secure information transmission. Firstly, a novel nonlinear synchronization scheme among multiple chaotic systems is defined based on vector polynomial to improve the complexity of the carrier signal, and then to enhance the attack resistance of the communication scheme. Secondly, a more flexible and accurate synchronization control technology is proposed so that the above vector-polynomial-based chaotic synchronization can be realized within a time that is predefined as a tunable control parameter. Subsequently, the theoretical derivation is carried out to prove the synchronization time in the above-mentioned synchronization control scheme can be set independently without being affected by the initial conditions or other control parameters. Finally, several simulation experiments on secure information transmission are presented to verify the efficiency and superiority of the designed chaotic synchronization scheme and synchronization control technology.
Ansiedade, Depressão, Estresse e sua Relação com a Qualidade e Vida de Pacientes com Câncer na Região Norte do Brasil
Authors: De Vasconcelos Galvão Elis Monique , Calheiros Paulo Renato Vitória , Di Tarique Barreto Crispim Pedro
Published: July 2021

Este estudo teve como objetivo verificar associações entre as variáveis sociodemográficas e clínicas, sintomas de depressão, ansiedade e estresse, e sua relação com a qualidade de vida em pacientes com câncer. A amostra foi constituída por 202 pessoas atendidas em instituto para tratamento oncológico na cidade de Porto Velho, Rondônia. Foram utilizados como instrumentos para coleta de dados um questionário sociodemográfico e clínico, a Escala de Depressão, Ansiedade e Estresse (DASS-21) e a Escala de Qualidade de Vida (EORTC-QLQ C30). Para explorar as relações conjuntas existentes foi realizada a Análise de Correspondência Múltipla (ACM) e para obter o grau de relacionamento entre as variáveis da DASS-21 e da EORTC-QLQ C30 foi utilizada a correlação linear de Spearman. Os resultados demonstraram alta prevalência de depressão, ansiedade e estresse nos pacientes oncológicos. As maiores prevalências desses sintomas associaram-se ao câncer uterino, ao sexo feminino, à realização de dois tipos de tratamentos e ao fato de morar sozinha. Quanto à qualidade de vida, apresentou-se com maiores prejuízos à medida que ocorreram aumento dos sintomas depressivos, ansiosos e estressores.
Medidas de Forças de Caráter para Crianças: revisão integrativa da literatura
Authors: Batista Helder Henrique Viana Santos , Noronha Ana Paula Porto , Queiroz Lorena Gonçalves
Published: July 2021

O objetivo do presente estudo foi identificar as medidas utilizadas para avaliar as forças de caráter em crianças de até 12 anos por meio de uma revisão integrativa de literatura. Considerou-se o período entre 2008 e 2020, sendo que a CAPES, a ScieLO e a Redalyc foram as bases de dados utilizadas. Foram analisados nove artigos, considerando ano de publicação, instrumentos utilizados, características amostrais e os construtos relacionados às forças. Os anos de 2013, 2014 e 2015 foram os que tiveram o maior número de publicações. As amostras dos estudos analisados foram compostas por estudantes. As variáveis associadas ao contexto escolar e construtos como a satisfação com a vida e o otimismo foram associados com maior frequência às forças de caráter. Além de ser o instrumento mais utilizado, o Values in Action-Youth parece ser o instrumento mais aceito para avaliar as forças em crianças. Conclui-se que o contexto escolar tem sido considerado um espaço importante para o desenvolvimento das forças pessoais de crianças, preservação da saúde e enfrentamento de problemas da vida.
Intervenções em Mindfulness para Síndrome de Burnout em Professores: uma revisão integrativa
Authors: Santos Karine David Andrade , Silva Joilson Pereira da
Published: July 2021

Esta revisão objetivou descrever e examinar os resultados das intervenções em mindfulness para síndrome de burnout em professores. As bases de dados acessadas para a coleta das evidências foram: Scopus, Web of Science, ERIC (ProQuest), BVS (BIREME) e PubMed Central: PMC. Parâmetros de inclusão e exclusão foram utilizados para a escolha dos estudos, cujos processos de avaliação foram apoiados pela plataforma Rayyan e, após as fases de seleção, dez artigos constituíram a amostra final deste levantamento. Os resultados apontaram que os programas MBSR (Mindfulness Based Stress Reduction) e CARE (Cultivating Awareness and Resilience in Education) foram os protocolos adotados nas intervenções. O primeiro foi o mais utilizado, com variações na quantidade das sessões e nos tipos de práticas de atenção plena realizadas. Os módulos relacionados à autocompaixão e compaixão e o treinamento da regulação emocional apresentaram incremento nos níveis de saúde mental, física e laboral dos professores. Recomenda-se que as futuras modalidades interventivas em mindfulness atentem para a identificação dos mecanismos e seus respectivos componentes de ação, nos programas propostos, e implementem critérios de avaliação e monitoramento da qualidade de suas intervenções.
Idosos Encarcerados no Brasil: uma revisão sistemática da literatura
Authors: Da Silva Dias Vilela Daniely , De Souza Brito Dias Cristina Maria , Sampaio Marisa Amorim
Published: July 2021

A população idosa nas penitenciárias brasileiras constitui fenômeno em ascensão. Estereótipos como “velho frágil e indefeso” permeiam o imaginário social e contribuem para a invisibilidade desse contingente. Esta revisão sistemática da literatura analisou artigos, teses e dissertações a partir da pergunta “O que foi publicado sobre o idoso encarcerado no Brasil nos últimos dez anos?”. Foram consultados periódicos indexados na SciELO, BVS Brasil, LILACS, PePSIC, Google Scholar, Portal de Periódicos CAPES e no Banco de Teses e Dissertações da CAPES. Foram selecionados para análise seis artigos e cinco dissertações - cinco estudos teóricos, três pesquisas empíricas e três relatos de experiência - organizados em categorias: a) O Sistema Penitenciário e os idosos encarcerados; b) Saúde da população idosa encarcerada; c) Percepção dos idosos encarcerados sobre o envelhecimento; d) Legislação e Políticas Públicas; e) Crimes cometidos por idosos. Os resultados indicam que o número de idosos cresce dentro e fora das penitenciárias. O idoso na condição de réu vivencia insegurança no âmbito penal, pois não há consenso em relação à idade nos documentos jurídicos. O Estado parece não conseguir garantir a integridade física e mental dessa população (em desacordo com as premissas dispostas no Estatuto do Idoso), dadas as precárias condições do Sistema Prisional.
Effective Cytotoxicity of Dendritic Cells against Established T Cell Lymphomas in Mice
Authors: Dubois Sigrid , Waldmann Thomas A , Müller Jürgen R
Published: July 2021

T cell lymphomas arise in mice that constitutively express a single TCR in the absence of NK cells. Upon TCR engagement these lymphomas are able to corrupt tumor surveillance by decreasing NK cell numbers. In this study, we investigate the outcome of interactions between these T cell lymphomas and dendritic cells. Bone marrow–derived dendritic cells mediated effective killing of T cell lymphomas after activation with IFN-γ and TLR ligands in culture. This cytotoxicity was independent of MHC compatibility. Cell lysis was reduced by the presence of the peroxynitrite inhibitors FeTTPS and L-NMMA, whereas inhibitors of apoptosis, death receptors, and degranulation were without effect, suggesting NO metabolites as the main mediators. When injected together with GM-CSF and R848 into lymphoma-bearing mice, in vitro–expanded bone marrow–derived dendritic cells caused significant survival increases. These data show that dendritic cell adaptive immunotherapy can be used as treatment against T cell lymphomas in mice.
Pigmentary Mammary Paget Disease: clinical, dermoscopical and histological challenge
Authors: D'Erme Angelo Massimiliano , Iozzo Roberta , Viacava Paolo , Janowska Agata , Dini Valentina , Romanelli Marco , Fidanzi Cristian , Bagnoni Giovanni
Published: July 2021

A very rare variant of MPD is the Pigmented Mammary Paget Disease (PMPD), first described by Culberson et al. in 1956. It is very difficult to distinguish this variant from melanoma both clinically and dermoscopically. The diagnosis is confirmed by histopathology and immunohistochemistry. Correct diagnosis is crucial for surgical treatment, which is different for these two diseases. We report the case of a 92-year-old woman, who presented an asymptomatic pigmented lesion of the right nipple and areola. The lesion was arisen for about 6 months and was suspected for melanoma because of clinical and dersmoscopic characteristics. Incisional biopsy revealed tumor cells, that proliferate in the major mammary ducts, and tumor cells in the overlying epidermis of the nipple, thus diagnosing pigmented mammary Paget disease (PMPD). The patient underwent radical mastectomy.
The use of the term ‘limnology’ and its scientometrics consequences for limnologists
Authors: Fontaneto Diego , Martínez Alejandro , Mammola Stefano , Marchetto Aldo
Published: July 2021

Jargon is the specialised vocabulary of any science: it allows the creation of new terms to define concepts and it removes ambiguity from scientific communication. Yet, it may also hinder understanding for a broader audience. Given that the Journal of Limnology has jargon in its title, we here investigate the impact of the term ‘limnology’ on the way limnologists work, publish their research, and attract the interest of other scientists. We do so by comparing scientometric features of papers published from 1965 to 2020 that used the term ‘limnology’ against papers on similar topics but that used the term ‘lake ecology’ or ‘hydrobiology’, and to the marine counterpart of papers that used the term ‘oceanography’. We found that papers using the term limnology score worse than those of the other topics in terms of both publication output and scientific impact. Limnologists may need to use other terms in addition to ‘limnology’ to reach a broader scientific audience.
Knowledge of the Female Athlete Triad and Relative Energy Deficiency in Sport Among Female Cross-Country Athletes and Support Staff
Authors: Lodge Melissa T. , Ackerman Kathryn E. , Garay Jessica
Published: July 2021

Context

Female endurance athletes exhibit an increased risk of the female athlete triad (Triad) and relative energy deficiency in sport (RED-S). The triad and RED-S are conditions that involve the health and performance consequences of low energy availability. Few authors of studies to date have assessed the knowledge that athletes, coaches, and athletic trainers (ATs) have regarding the Triad or RED-S. Proper education has been shown to be effective in increasing knowledge of sports medicine concerns for athletes, yet no known continuing education programs for the Triad or RED-S exist at collegiate institutions.

Objective

To assess the knowledge, confidence, and educational impact of identifying, screening, treating, and preventing the Triad or RED-S.

Design

Cross-sectional study.

Setting

An evidence-based online survey was developed and administered via Qualtrics.

Patients or Other Participants

Female collegiate cross-country athletes (n = 275, age = 20 ± 1 years), collegiate cross-country coaches (n = 55, age = 34 ± 9 years), and ATs working with cross-country teams (n = 30, age = 36 ± 11 years).

Main Outcome Measure(s)

Knowledge, confidence, and educational impact scores were assessed among groups using analysis of variance. Independent t tests were calculated to determine differences in impact scores between people who had or had not received education on the topic.

Results

Female cross-country athletes' total knowledge, confidence, and educational impact scores (mean scores = 25.00 ± 5.27, 95.42 ± 28.83, and 18.81 ± 7.05, respectively) were different from those of coaches (mean scores = 26.92 ± 5.02, 111.35 ± 24.14, and 22.41 ± 6.33, respectively) and ATs (mean scores = 28.66 ± 4.02, 117.67 ± 22.53, and 23.93 ± 5.69, respectively; P < .05).

Conclusions

Knowledge, confidence, and educational impact scores regarding Triad or RED-S were lowest in female cross-country athletes and highest in ATs. These findings support the call for education, which should be regarded as the primary tool for increasing knowledge, to improve the prevention and treatment of the Triad or RED-S.
Study on Risk Factors of Peripheral Neuropathy in Type 2 Diabetes Mellitus and Establishment of Prediction Model
Authors: Wu Birong , Niu Zheyun , Hu Fan
Published: July 2021

Background: Diabetic peripheral neuropathy (DPN) is one of the most serious complications of type 2 diabetes mellitus (T2DM). DPN increases the risk of ulcers, foot infections, and noninvasive amputations, ultimately leading to long-term disability.Methods: Seven hundred patients with T2DM were investigated from 2013 to 2017 in the Sanlin community by obtaining basic data from the electronic medical record system (EMRS). From September 2018 to July 2019, 681 patients (19 missing) were investigated using a questionnaire, physical examination, biochemical index test, and follow-up Toronto clinical scoring system (TCSS) test. Patients with a TCSS score ≥6 points were diagnosed with DPN. After removing missing values, 612 patients were divided into groups in a 3:1 ratio for external validation. Using different Lasso analyses (misclassification error, mean squared error, –2log-likelihood, and area under curve) and a logistic regression analysis of the training set, models A, B, C, and D were established. The receiver operating characteristic (ROC) curve, calibration plot, dynamic component analysis (DCA) measurements, net classification improvement (NRI) and integrated discrimination improvement (IDI) were used to validate discrimination and clinical practicality of the model.Results: Through data analysis, model A (containing four factors), model B (containing five factors), model C (containing seven factors), and model D (containing seven factors) were built. After calibration, ROC curve, DCA, NRI and IDI, models C and D exhibited better accuracy and greater predictive power.Conclusion: Four prediction models were established to assist with the early screening of DPN in patients with T2DM. The influencing factors in model C and D are more important factors for patients with T2DM diagnosed with DPN.
Research trends related to childhood and adolescent cancer survivors in South Korea using word co-occurrence network analysis
Authors: Kang Kyung-Ah , Han Suk Jung , Chun Jiyoung , Kim Hyun-Yong
Published: July 2021

Purpose: This study analyzed research trends related to childhood and adolescent cancer survivors (CACS) using word co-occurrence network analysis on studies registered in the Korean Citation Index (KCI).Methods: This word co-occurrence network analysis study explored major research trends by constructing a network based on relationships between keywords (semantic morphemes) in the abstracts of published articles. Research articles published in the KCI over the past 10 years were collected using the Biblio Data Collector tool included in the NetMiner Program (version 4), using "cancer survivors", "adolescent", and "child" as the main search terms. After pre-processing, analyses were conducted on centrality (degree and eigenvector), cohesion (community), and topic modeling.Results: For centrality, the top 10 keywords included "treatment", "factor", "intervention", "group", "radiotherapy", "health", "risk", "measurement", "outcome", and "quality of life". In terms of cohesion and topic analysis, three categories were identified as the major research trends: "treatment and complications", "adaptation and support needs", and "management and quality of life".Conclusion: The keywords from the three main categories reflected interdisciplinary identification. Many studies on adaptation and support needs were identified in our analysis of nursing literature. Further research on managing and evaluating the quality of life among CACS must also be conducted.
A study on depression among adolescents with asthma in South Korea using the 15th Korea Youth Risk Behaviour Web-Based Survey
Authors: Park Jin H , Kim Mi Jin
Published: July 2021

Purpose: This study investigated the factors that influence depression in adolescents diagnosed with asthma in South Korea, providing basic data supporting efforts to improve adolescents' mental health.Methods: Multiple regression analysis was conducted on 4,020 subjects who had been diagnosed with lifelong asthma among the 57,303 respondents to the 15th Korea Youth Risk Behaviour Web-Based Survey from 2019.Results: The participants were more likely to have depression if they were female, in middle school, their academic achievement was poor, they were drinkers or smokers, if they felt a very high amount of stress, and if they experienced very inadequate recovery from fatigue. Adolescents with asthma were 9.00 times more likely to experience depression when they felt a very high amount of stress (95% confidence interval [CI]= 5.51-14.69, p<.001) than when they felt no stress.Conclusion: Given these factors, measures to improve the mental health of adolescents should be developed and expanded, especially to decrease their stress levels. A separate program that is different from the school's regular health curriculum should be developed to manage the stress levels of adolescents with asthma, such as an after-school program or a program conducted at a local community centre.
First-time fathers' experiences during their transition to parenthood: A study of Korean fathers
Authors: Noh Nan Iee
Published: July 2021

Purpose: This study was conducted to explore first-time fathers' experiences during their transition to parenthood in South Korea.Methods: Data were collected from September 2019 to February 2020 through in-depth interviews that were conducted individually with 12 participants. First-time fathers with children under 2 months of age were recruited. Verbatim transcripts were analyzed using Colaizzi's phenomenological method.Results: Four theme clusters were identified: Preparing to become a father, challenges of becoming a father, motivation to foster familial bonds, and acknowledgement of fatherhood.Conclusion: These findings suggest that Korean first-time fathers prepared to practice parenthood through prenatal education, taegyo, and feeling bonds with their new baby. They recognized their identity as fathers and experienced self-growth. These results would be beneficial for health professionals in developing perinatal care programs, and the results provide basic data for studies on fathers and families during the transition to parenthood.
Considerations for crossover design in clinical study
Authors: Lim Chi-Yeon , In Junyong
Published: July 2021

This article introduces a crossover design that is often used in clinical studies, with the advantage of comparing treatment effects within one study subject. In particular, the advantages and disadvantages of the two-period, two-sequence crossover design (2 × 2 or AB/BA crossover design), which is widely used in clinical practice, are identified, and the elements necessary for analysis are introduced. This article explains the carryover effect, period effect, sequence effect, and period-by-treatment interaction in a crossover design and examines the analysis commands of SAS along with example data. After confirming the carryover effect using a general linear model, the treatment effect is analyzed using a linear mixed effect model.
Vitamin D-Binding Protein is Involved in the Pathogenesis of Preeclampsia by Inhibiting the Tyrosine Phosphorylation of Vascular Endothelial Growth Factor Receptor-2 in Endothelial Cells
Authors: Lu Ting-Feng , Ye Yun-Zhen , Li Xiao-Tian , Zhang Ying
Published: July 2021

Abstract

Objective:

The role of Vitamin D-binding protein (DBP) in preeclampsia (PE) pathogenesis is unknown. In this study, we compared the expression of DBP in the placentas of PE patients with the placentas of normotensive pregnant women with placenta previa controls, and aimed to explore the effect of DBP on endothelial cells (ECs) and the underlying mechanism.

Methods:

DBP expression in placental tissues collected from PE patients and controls was evaluated by immunohistochemistry. The downregulation and upregulation of DBP expression in HTR-8/SVneo cells were examined using DBP-targeting small interfering RNA (siRNA) and DBP-expression vector, respectively. The conditioned media of these DBP-overexpressing and DBP-siRNA HTR-8/SVneo cells were collected and added to human umbilical vein EC (HUVEC) cultures. Angiogenic effects on HUVECs were assessed by tube formation assays, and the proliferation and migration of HUVECs were examined using the Real-Time Cell Analyzer. The expression of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR)-2, as well as the phosphorylation of different residues of VEGFR-2 in HUVECs, were determined by western blotting.

Results:

DBP expression was significantly increased in the placental tissues collected from PE patients. The conditioned medium of DBP-overexpressing HTR-8/SVneo cells potently inhibited tube formation by HUVECs, in addition to their proliferation and migration. Furthermore, treatment of HUVECs with the conditioned medium of DBP-overexpressing HTR-8/SVneo cells decreased the phosphorylation of VEGFR-2 at tyrosine 996, whereas the treatment of these cells with the conditioned medium of DBP-siRNA HTR-8/SVneo cells increased the phosphorylation of VEGFR-2 at tyrosine 951, 996, and 1,175.

Conclusions:

The expression of DBP is increased in the placentas of PE patients. DBP plays potential roles in endothelial dysfunction, which contributes to PE development, by inhibiting tyrosine phosphorylation of VEGFR-2 in ECs.
A rare case of acorea
Authors: Priyambada Parul , Prabu Rajesh V. , Wasnik Rajlaxmi B. , Ranjini H.
Published: July 2021

Acorea is a congenital anomaly in which there is an absence of pupillary aperture. It is known to have an autosomal dominant inheritance and is associated with microphthalmos, cataract, and iridocorneal dysgenesis. It is caused when the mesodermal tissue of the iris fails to regress during embryogenesis. The lack of pupillary aperture prevents light entering the eye, often causing stimulus deprivation amblyopia. This case describes one such patient with acorea in the right eye with dense amblyopia.
Syzygium cumini (jamun) fruit-extracted phytochemicals exert anti-proliferative effect on ovarian cancer cells
Authors: Li Li , Mangali Sureshbabu , Kour Navneet , Dasari Deepika , Ghatage Trupti , Sharma Vikas , Dhar Arti , Bhat Audesh
Published: July 2021

Background:

The medicinal properties of Syzygium sp., especially the antidiabetic property, date back to the ancient times. However, in the recent past, extracts from different parts of the Syzygium sp. have demonstrated promising anticancer activities in diverse cancer types, and now, attempts are being made to identify the active phytochemicals.

Aims and Objectives:

In this study, we intended to test the anticancer properties of phytochemicals extracted from the fruit of Syzygium cumini plant in ovarian cancer cells.

Materials and Methods:

A total of nine phytochemicals extracted from the S. cumini fruits using chloroform were tested for their anticancer activity in the ovarian cancer cell line PA-1. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide tetrazolium assay was performed to calculate the 50% inhibition (IC50) concentration and cell cytotoxicity values. Cell scratch assay was performed to assess the proliferation inhibition activity of the phytochemicals. Cisplatin was used as positive control.

Results:

Out of the nine phytochemicals tested, quercetin (QC), gallic acid (GA), and oleanolic acid (OA) were found active. QC and GA were most effective with more than 90% cell cytotoxicity at 2.5 µ g/ml and above concentrations and OA moderately effective up to 5 µg/ml serial concentrations. Cell proliferation was significantly inhibited by QC and GA and moderately but significantly by OA.

Conclusion:

Our data demonstrate the anticancer activity of QC, GA, and OA phytochemicals, which is consistent with the previous reports. However, this is the first report showing the anticancer activity of these phytochemicals derived from S. cumini in the ovarian cancer cells. These data suggest that there is a potential to develop these phytochemicals as anticancer therapeutic agents either as monotherapeutic agents or in combination with commonly used chemotherapeutic agents, which needs to be explored.