bluuebunny/crossref_metadata_2025 huggingface dataset:
Flexible and anisotropically conductive sandwich film by assembly of liquid silicone rubber and cobalt coated glass fiber composites via magnetic field inducement
Authors: zhou ruihua
Published: February 2021

In this work, we have prepared electromagnetic cobalt coated glass fiber (Co@GF) composite via electroless plating method firstly. And then a conductive sandwich flexible film consisted of Co@GF composite and liquid silicone rubber (RTV-2) is successfully formed, through tape casting method at room temperature. Based on the perfect coating and excellent electrical conductivity of Co@GF composite, the resultant RTV-2/Co@GF/RTV-2 sandwich flexible film shows high electrical conductivity of 0.264 Ω·cm and can stretch to 100% ( of 4.40 Ω·cm) without obvious fracture. When the magnetic field was applied to the curing process, the electromagnetic Co@GF composite aligned automatically in the RTV-2 matrix on account of its ferromagnetic nature. The as-prepared film shows anisotropy in electrical performance. The volume resistivity parallel to the magnetic field direction is about two times lower than that of perpendicular direction. The maximum difference in volume resistivity (ρ∥ of 0.768 Ω·cm and ρ⊥ of 1.549 Ω·cm) is obtained at magnetic field intensity of 800 mT. In addition, a certain magnetic field intensity at 100mT is helpful to improve the electrical conductivity of the as-obtained sandwich film. The anisotropic RTV-2/Co@GF/RTV-2 sandwich flexible film would be considered as promising flexible electronic sensor where discrepant sensing sensitivity is required in orthogonal directions.
Genetic diversity analysis in indigenous rice (Oryza sativa L.) germplasm for Bacterial Leaf Blight (Xanthomonas oryzae pv. Oryzae) using resistance genes linked markers
Authors: . Khannetah K. R , S. Ramchander , T Andrew Peter Leon M. , D. Shobha , S. Saravanan , R. Kannan , Yasin Jeshima Khan , M. Arumugam Pillai
Published: February 2021

Among rice ( Oryza sativa L.) diseases, bacterial blight (BB), caused by Xanthomonas oryza pv. Oryzae , plays a pivotal role in decreasing rice yield. BB is reported to be the most serious constraint to improving rice yield. The present investigation assessed the potentiality of bacterial blight resistance and molecular characterization of 100 rice accessions for four major BB resistance genes, viz., Xa4, xa5, xa13 and Xa21 . Disease screening was carried out under glasshouse conditions using a BB culture isolated from BB-infected rice fields through the leaf clipping method. Analyses of 13 BB resistance genes linked with polymorphic microsatellites markers indicated the presence of single-, two-, three- and four-gene combinations of xa5, xa13, Xa4 and Xa21 . We found four accessions to be resistant; 34 accessions to be moderately resistant; 49 accessions to be moderately susceptible and 13 accessions to be susceptible. Among the resistant lines, IR12L110, Namcheonbyeo, Dhalaheera and SahbhagiDhan recorded a minimum lesion length of 3.7cm, 4.2cm, 4.67cm and 8.3 cm, respectively. Phylogenetic tree, constructed using molecular data, grouped the rice germplasm into four major clusters. R genes xa 5 and Xa4 contributed 14 positive compatible R genes, each belonging to 28 germplasm for BB resistance. The potential genetic resources identified as resistant to BB can be used as donors for the improvement of rice BB resistance in rice breeding programs.
Laser cladding treatment for refurbishing disc brake rotors – environmental and tribological analysis
Authors: Olofsson Ulf , Lyu Yezhe , Åström Anna Hedlund , Wahlström Jens , Senad Dizdar , Nogueira Ana Paula Gomes , Gialanella Stefano
Published: February 2021

In this study, grey cast iron disc brake rotors are refurbished by adding a surface layer through laser cladding. Current methods to deal with replaced rotors mainly include re-melting, with a minority fraction disposed in landfill. Both approaches result in a huge waste of resources and an increase in CO 2 footprint. From a sustainable point of view, this study aims to evaluate the feasibility of refurbishing brake rotors by a combined environmental and tribological performance approach. A streamlined life cycle assessment is conducted to compare the environmental impacts between producing virgin grey cast iron brake rotors and refurbishing replaced brake rotors by laser cladding. It turns out that the energy consumption and CO 2 footprint of the laser cladding refurbished brake rotors are 80% and 90% less than the virgin brake rotors. The results show that the refurbished brake rotor yields higher friction compared to the original cast iron utilizing the same pad material. The wear and particle emissions of the disc brake contact are in this study higher for the laser cladded one compared to the original cast iron one.
PO2RDF: Representation of Real-world Data for Precision Oncology Using Resource Description Framework
Authors: ZHAO Yiqing , Dimou Anastasios , Shen Feichen , Zong Nansu , Davila Jaime I. , Liu Hongfang , Wang Chen
Published: February 2021

Background: Next-generation sequencing provides comprehensive information about individuals’ genetic makeup and is commonplace in precision oncology practice. Due to the heterogeneity of individual patient’s disease conditions and treatment journeys, not all targeted therapies were initiated despite actionable mutations. To better understand and support the clinical decision-making process in precision oncology, there is a need to examine real-world associations of patients’ genetic information and treatment choice.Methods: To fill the gap of insufficient use of real-world data (RWD) in electronic health records (EHRs), we generated a single Resource Description Framework (RDF) resource, called PO2RDF (precision oncology to RDF) by integrating information regarding gene, variant, disease, and drug from genetic reports and EHRs. Results: There are total 2,309,014 triples contained in the PO2RDF. Among them 32,815 triples are related to Gene, 34,695 triples are related to Variant, 8,787 triples are related to Disease, 26,154 triples are related to Drug. We performed one use case analysis to demonstrate the usability of the PO2RDF: we examined real-world associations between EGFR mutations and targeted therapies to confirm existing knowledge and detect off-label use. Conclusions: In conclusion, our work proposed to use RDF to organize and distribute clinical RWD that is otherwise inaccessible externally. Our work serves as a pilot study that will lead to new clinical applications and could ultimately stimulate progress in the field of precision oncology.
Large Core Optical Elastomer Splitter Fabricated by Using 3D Printing Pattern
Authors: Prajzler Václav , Zavrel Jakub
Published: February 2021

The design, fabrication and properties of the large core 1x2Y optical planar splitter using optical elastomers for cladding and core is demonstrated. The splitters were designed by beam propagation method optimized for operation wavelength 650 nm. The splitters were fabricated using epoxy polymer pattern fabricated by Stereolithography 3D printing technology. The dimensions of the splitters were optimized for assembling optical fiber with core diameter 500 µm. The splitter shows optical losses around 1.48 dB at 650 nm, 1.18 dB at 850, 1.82 dB at 1300 nm and 2.12 dB at 1550 nm at room temperature.
Prostaglandin E2 Enhances Aged Hematopoietic Stem Cell Function
Authors: Patterson Andrea M. , Plett P. Artur , Sampson Carol H. , Simpson Edward , Liu Yunlong , Pelus Louis M. , Orschell Christie M.
Published: February 2021

Aging of hematopoiesis is associated with increased frequency and clonality of hematopoietic stem cells (HSCs), along with functional compromise and myeloid bias, with donor age being a significant variable in survival after HSC transplantation. No clinical methods currently exist to enhance aged HSC function, and little is known regarding how aging affects molecular responses of HSCs to biological stimuli. Exposure of HSCs from young fish, mice, nonhuman primates, and humans to 16,16-dimethyl prostaglandin E2 (dmPGE2) enhances transplantation, but the effect of dmPGE2 on aged HSCs is unknown. Here we show that ex vivo pulse of bone marrow cells from young adult (3 mo) and aged (25 mo) mice with dmPGE2 prior to serial competitive transplantation significantly enhanced long-term repopulation from aged grafts in primary and secondary transplantation (27% increase in chimerism) to a similar degree as young grafts (21% increase in chimerism; both p<0.05). RNA sequencing of phenotypically-isolated HSCs indicated that the molecular responses to dmPGE2 are similar in young and old, including CREB1 activation and increased cell survival and homeostasis. Common genes within these pathways identified likely key mediators of HSC enhancement by dmPGE2 and age-related signaling differences. HSC expression of the PGE2 receptor EP4, implicated in HSC function, increased with age in both mRNA and surface protein. This work suggests that aging does not alter the major dmPGE2 response pathways in HSCs which mediate enhancement of both young and old HSC function, with significant implications for expanding the therapeutic potential of elderly HSC transplantation.
Aquaporin 3 promotes human extravillous trophoblast migration and invasion
Authors: Nong Yingqi , Li Shifen , Liu Wenjuan , Zhang Xiqian , Fan Lin , Chen Ye , Huang Qianwen , Zhang Qianyu , Liu Fenghua
Published: February 2021

Problem: Does aquaporin 3 (AQP3) affect the migration and invasion of human extravillous trophoblast (HTR8/Svneo) cells?Method of Study: A lentivirus infection system was used to construct stable cell lines with either AQP3 knockdown or overexpression. RT-PCR and western blotting were used to verify the efficiencies of AQP3 knockdown or overexpression in HTR8/Svneo cells at mRNA and protein levels, respectively. Cell Counting Kit-8 and flow cytometry assays were used to detect the influence of AQP3 knockdown or overexpression on proliferation and apoptosis of HTR8/Svneo cells. In addition, wound healing and Transwell invasion assays were used to detect the effects of AQP3 knockdown or overexpression on migration and invasion capabilities of HTR8/Svneo cells. An Agilent gene chip was used to screen for significant differentially expressed genes after AQP3 knockdown. Finally, mechanisms by which AQP3 influences the migration and invasion of HTR8/Svneo cells were explored using bioinformatic analysis.Results: Compared with controls, migration and invasion capabilities of HTR8/Svneo cells were significantly reduced after AQP3 knockdown, and significantly increased after AQP3 overexpression. Subsequent bioinformatic analysis of gene chip expression profiles indicated downregulation of genes related to adhesion such as PDGF-B, as well as signaling pathways (such as PIK3/AKT, NF-κB, and TNF) after AQP3 knockdown. Conclusions: AQP3 could significantly promote migration and invasion capabilities of human extravillous trophoblasts, it may mediate embryo invasion and adhesion to endometrium by regulating PDGF-B, PIK3/AKT signaling pathways, although this requires further verification.
An Investigation of Item Position Effects by Means of IRT-Based Differential Item Functioning Methods
Authors: SOYSAL Sümeyra , YILMAZ KOĞAR Esin
Published: February 2021

In this study, whether item position effects lead to DIF in the condition where different test booklets are used was investigated. To do this the methods of Lord’s chi-square and Raju’s unsigned area with the 3PL model under with and without item purification were used. When the performance of the methods was compared, it was revealed that generally, the method of Lord’s chi-square identified more items with DIF than did the method of Raju’s unsigned area. The differentiation of the booklets with respect to item position resulted in a higher number of items displaying DIF with item purification conditions. Based on the findings of the present study, to avoid the occurrence of DIF due to item position effects, it is recommended to position the same items across different booklets in similar locations when forming different booklets.
Episode One: Introduction
Authors: Shah Rajni , Righteous Ria , Singh Julietta , 周 Gibbons Fili
Published: February 2021

In this introductory episode, Rajni Shah, Ria Righteous, and Julietta Singh reflect on their time working together towards what was originally planned as a symposium (also called how to think) and has (for) now been translated into this podcast.
The episode begins with an extract from a meditation led by Ria Righteous, followed by Julietta, then Ria, then Rajni reflecting on where they are situated and what’s present for each of them. The episode includes short narrations in which Rajni introduces some of the context for this conversation and the podcast as a whole. Most of the episode is composed of extracts from a reflective conversation in which Rajni, Julietta, and Ria touch on themes of home, grief, friendship, disaporic identities, listening, trust, and preparing for a pandemic world.
Click here for full episode and credits.
Episode Five: Omikemi
Authors: Shah Rajni , Omikemi  , 周 Gibbons Fili
Published: February 2021

In this final episode of the podcast, Rajni Shah and Omikemi engage in a long, slow, wide conversation, in which they reflect on the entanglements between the felt world of lived experiences and the systems within which we live our lives. Infused by the sounds and shapes of the ocean, this episode feels intimate and visceral – and perhaps more than any of the others, like an invitation to eavesdrop on a conversation between friends.

In the accompanying offering, Omikemi invites listeners to spend time with a question that was present for them at the time of recording.

Full credits and transcript for this episode will be published when the episode is released on 27 April 2021.
Estigmatización social en el ámbito escolar generada por un diagnóstico psicológico
Authors: Cano Agudelo Daniel , Villegas Grajales Daniela , González Pérez Jessica , Montoya Mejía Karen Margarita
Published: February 2021

La presente investigación surge de la pregunta por la estigmatización social en el ámbito escolar, generada por un diagnóstico psicológico. El contexto educativo es escenario de diversas dinámicas que influyen en el proceso de desarrollo de los estudiantes, allí se viven etapas de transición como el paso de primaria a bachillerato, en un período de la vida en el cual el adolescente está en plena construcción de su identidad. Es una etapa de adaptación al entorno, siendo éste un período de vulnerabilidad que puede ser afectado significativamente cuando además, el estudiante lleva consigo un diagnóstico psicológico que puede generar estigmatización social. Esta investigación se llevó a cabo a partir de un rastreo teórico y un estudio de caso único, en el cual se le realizó una entrevista a un estudiante con un diagnóstico psicológico establecido, otra a su madre, una a un docente y finalmente a dos psicólogos de la institución educativa. Se lograron identificar las categorías de diagnóstico, sujeto escolar e identidad en relación a la estigmatización; y a partir de un trabajo riguroso de rastreo y análisis, se concluyó que tener un diagnóstico psicológico sí está altamente relacionado con la estigmatización social y la rotulación por parte de otras personas, lo cual tiene implicaciones importantes en el desarrollo psicosocial de la persona estigmatizada, generando repercusiones negativas como baja autoestima, inseguridad, depresión, aislamiento, agresividad, estrés, temor social, timidez, sensación de incapacidad, entre otras afectaciones que pueden surgir a partir de procesos de estigmatización.
Consumo de sustancias psicoactivas desde la perspectiva de la terapia familiar
Authors: Pedroza Molina Diana Yojaida , Taborda Mazo Diana Patricia , Varela Chacón Juliana
Published: February 2021

El consumo de sustancias psicoactivas, al considerarse una problemática contemporánea que genera alto impacto en la salud pública asociado al costo de la atención, suscita interés sobre Pedroza Molina, D. Y., Taborda Mazo, D. P. y Varela Chacón, J. (2020). La presente revisión bibliográfica, realizada desde el enfoque cualitativo-hermenéutico, plantea el análisis de las conceptualizaciones sobre el consumo de SPA desarrolladas en el ámbito de la terapia familiar, la identificación de la incidencia de las relaciones familiares en el consumo de sustancias psicoactivas y, por último, la descripción de propuestas de intervención desde la terapia familiar para familias en las que hay miembros consumidores de SPA. Dentro de los hallazgos se encuentra evidencia de las conceptualizaciones, implicaciones de la familia y propuestas de intervención en la revisión realizada, a partir de lo cual es posible señalar que, si bien no hay un consenso frente a la denominación del consumo desde esta disciplina –ya que se usan indistintamente lo términos consumidor, drogodependiente, toxicómano, adicto, drogadicto–, se halla que independientemente de la escuela o modelo teórico existe acuerdo al conceptualizar el consumo como síntoma que emerge para garantizar la homeostasis familiar en un sistema sufriente. De igual forma, la familia tiene una alta incidencia dentro de la etiología de la situación de consumo y el proceso que genera la mantención del mismo, por lo que es claro que su implicación debe ser alta en el tratamiento y la recuperación. Se concluye que desde la terapia familiar existen diversas propuestas de intervención para abordar el tema de la adicción a SPA, que han mostrado ser efectivas y que la familia al estar involucrada en la génesis, mantenimiento y recuperación de la adicción, debe ser un foco central de la intervención.
Características neuro-psicopedagógicas de las dificultades de aprendizaje escolar: un estudio de caso
Authors: Gaviria Jaramillo Natalia , Salazar Acosta Ana María , Deossa Cañas María Clara , Rincón Barreto Dubis Marcela
Published: February 2021

Este artículo tiene como objetivo presentar las características neuropsicopedagógicas de un niño con dificultades escolares y de comportamiento. Se llevó a cabo un estudio de caso con un participante de 11 años de edad, quien durante la investigación cursaba el grado quinto de básica primaria en una institución educativa de carácter privado del municipio de Itagüí, Antioquia. Los instrumentos aplicados para la evaluación fueron: el Test Breve de Inteligencia de KAUFMAN (K-BIT), la Batería Psicopedagógica EVALÚA - 5, el Cuestionario de Depresión para Niños (CDS) y una entrevista semiestructurada para padres y docentes, relacionada con los aspectos del desarrollo, el aprendizaje y la conducta del estudiante. Los resultados demostraron que el niño presentaba un coeficiente intelectual dentro de los parámetros normales y las principales dificultades se encontraron en el contexto familiar-social, lo que permitió evidenciar que el rendimiento escolar es el resultado de la interacción de diferentes factores que abarcan componentes cognitivos, del neurodesarrollo, emocionales, familiares y contextuales. Así mismo, se evidenció que las dificultades en el comportamiento asociadas al contexto escolar no siempre están relacionadas con trastornos del aprendizaje o de la conducta. Se hace necesaria la obtención de este tipo de perfiles neuropsicopedagógicos con el fin de establecer rutas de intervención pertinentes y eficaces que incorporen las características cognitivas individuales, los vínculos socio afectivos, el entorno social, escolar, y la dinámica familiar del estudiante.
Protesta social y movilizaciones como contextos de interés para la psicología social en Nuestra América
Authors: Bonilla Daniel
Published: February 2021

Se han podido identificar una serie de protestas y manifestaciones alrededor del mundo que han afectado las diferentes dinámicas sociales. Esto puede deberse al continuo desencanto de los modelos hegemónicos a los cuales estamos expuestos. En este sentido, el presente documento busca acercar la discusión al campo de la psicología social, más precisamente, contribuir a la reflexión sobre los intereses y oportunidades para el trabajo en contextos sociales, pensando en posibilidades de acción y transformación que se relacionan con la protesta social y la movilización.
El encuentro como escenario del saber
Authors: Gaitán Arbeláez Daniela
Published: February 2021

Ante la ruptura que ha sido evidenciada entre la razón y el sentir, algunos autores han manifestado la importancia de rescatar el componente afectivo y subjetivo como un elemento vital para la creación del conocimiento. Es por esto que en el presente ensayo se pretende abordar las ideas expuestas en la emocionante ponencia del profesor Serge Gougbèmon en el XIII Congreso Internacional de Filosofía Intercultural, quien retoma el legado de Emanuel Lévinas sobre la otredad y la concepción de diversos mundos, y nos recuerda, a nosotros estudiantes, la importancia de estar atentos ante las múltiples manifestaciones del saber que se encuentran desde las conversaciones aparentemente banales, hasta en las líneas del rostro.
El autocuidado como un componente de la salud mental del psicólogo desde una perspectiva biopsicosocial
Authors: Holguín Lezcano Alejandra , Arroyave González Lucero , Ramírez Torres Verónica , Echeverry Largo William Alberto , Rodríguez Bustamante Alexander
Published: February 2021

El presente artículo pretende describir la importancia de la competencia del autocuidadoen la salud mental de los profesionales de psicología, desde una perspectiva biopsicosocial,reflexionando acerca de cómo la personalidad, la construcción social y la praxisinfluyen en el autocuidado. La revisión teórica se hizo a partir de un enfoque cualitativo, desde la perspectiva hermenéutica; múltiples autores continúan apuntando a lo vital que resulta ser el desarrollo de habilidades adquiridas en el ejercicio académico de la formación de los futuros psicólogos; sin embargo, es en el ejercicio profesional donde se adquieren no sólo las destrezas, sino las herramientas integradoras frente a lo que el quehacer profesional requiere, una vez se inicia en el trabajo de campo. Se infiere, entonces, a modo de conclusión, que el psicólogo tiene la responsabilidad de asumir el autocuidado como una competencia, en pro de su bienestar y su ejercicio profesional;tarea que no podrá ser asumida en la coparticipación de las diversas agremiaciones en pro de la salud mental y el autocuidado.
ИЗУЧЕНИЕ ГЕМОСТАТИЧЕСКОЙ АКТИВНОСТИ КРОВООСТАНАВЛИВАЮЩИХ ИМПЛАНТОВ В ЭКСПЕРИМЕНТЕ IN VITRO
Authors: Липатов В.А , Сотников К.А. , Северинов Д.А. , Косоголов М.В. , Писковитина С.Г. , Гладнева С.Ю. , Малетин С.Э.
Published: February 2021

Stopping bleeding during injuries, planned and emergency surgical interventions is a difficult and not completely resolved problem. Accordingly, in modern surgery, the most promising direction is the development of new drugs that affect the hemostatic system and locally acting hemostatic agents. This article presents the results of the research on the comparative analysis of the ability of application hemostatic agents to form a blood clot in the in vitro experiment. The hemostatic properties of the following agents were studied: sponge implants based on sodium salt of carboxymethyl cellulose in two versions: unmodified and thermostabilized, hemostatic collagen sponge, and «Tachocomb» hemostatic sponge. The experiment was performed using stabilized blood citrate of 10 volunteer donors, which was recalcification subsequently, on an APG2-02-P coaguometer. In this research, we confirmed the effectiveness of this technique for the comparative analysis of hemostatic implants. In addition, the results of the research showed that all the samples used by us significantly reduce the coagulation time in the experiment compared with the control.
ВОЗМОЖНОСТИ ЭНДОСКОПИИ ПРИ КРОВОТЕЧЕНИЯХ ИЗ «ТРУДНЫХ» ЯЗВ ЖЕЛУДКА
Authors: М.Ш. Хакимов , У.И. Маткулиев , Ш.Э. Ашуров , Ж.Х. Кушиев , Ж.К. Дехконов
Published: February 2021

Stomach ulcer is one of the most severe and unpredictable diseases of the gastrointestinal tract. The greatest danger in peptic ulcer disease is its complications, such as perforation of the ulcer, penetration into another organ, bleeding. Thanks to modern technical advances in medicine, surgeons have increasingly preferred minimally invasive methods of treating this disease.
ПРЕДПОСЫЛКИ К ОРГАНИЗАЦИИ СЛЕЖЕНИЯ ЗА РАСПРОСТРАНЕННОСТЬЮ ВИРУСА ПАПИЛЛОМЫ ЧЕЛОВЕКА СРЕДИ ПОДРОСТКОВ В РЕСПУБЛИКЕ УЗБЕКИСТАН
Authors: Ж.А. Рахманова , И.П Шарипова
Published: February 2021

The prevalence of the virus using epidemiological methods of investigation of human papilloma virus has been studied among adolescents of Uzbekistan. The data on the background prevalence of human papilloma virus makes possible to evaluate the effectiveness of HPV vaccination immediately after implementation
ИНФОРМАЦИОННЫЕ ПОТРЕБНОСТИ СТУДЕНТОВ-МЕДИКОВ В ВОПРОСАХ ПРОФИЛАКТИКИ ВИЧ В ЗАВИСИМОСТИ ОТ ИЗУЧЕНИЯ КЛИНИЧЕСКИХ ДИСЦИПЛИН И ВЫРАЖЕННОСТИ ЛИДЕРСКИХ КАЧЕСТВ
Authors: В.И. Тимошилов , Н.В. Шеставина , А.Д. Мурских , Е.З. Чикваидзе , Д.И. Гаврикова , А.К. Гавриков
Published: February 2021

In connection with the intensive growth of HIV infection in the Russian Federation, it is necessary to analyze and draw conclusions, what tools can influence this growth. This article considered the information needs of medical students in HIV prevention depending on the stage of training of students. To this end, we interviewed 200 students of KSMU of various courses. The degree of demand for each section of information was assessed on a 10-point scale. The difference in the distribution of responses was estimated using χ2, the prevalence of individual responses (extensive indicators) was compared according to the student's criterion. Based on our research, it was revealed that it is necessary to train and engage in volunteer activities for HIV prevention students of 4-6 courses, demonstrating leadership and organizational qualities, and within the framework of the" volunteer school" to pay special attention to the issues that have the highest rating among students.
The Putative Adverse Effects of Bisphenol A on Autoimmune Diseases
Authors: Sharif Kassem , Kurnick Adam , Coplan Louis , Alexander Matthew , Watad Abdulla , Amital Howard , Shoenfeld Yehuda
Published: February 2021

:

Bisphenol A (BPA) is a monomer that is widely used in the manufacturing of polycarbonate
plastics (including storage plastics and baby bottles) and is considered to be one of the most
widely used synthetic compounds in the manufacturing industry. Exposure to BPA mainly occurs
after oral ingestion and results from leaks into food and water from plastic containers. According to
epidemiological data, exposure is widespread and estimated to occur in 90% of individuals. BPA
exhibits pleiotropic and estrogen-like effects; thus, it is considered an endocrine-disrupting chemical.
A growing body of evidence highlights the role of BPA in modulating immune responses and
signaling pathways, which results in a proinflammatory response by enhancing the differential polarization
of immune cells and cytokine production profile to one that is consistent with proinflammation.
Indeed, epidemiological studies have uncovered associations between several autoimmune
diseases and BPA exposure. Data from animal models provided consistent evidence, which highlighted
the role of BPA in the pathogenesis, exacerbation, and perpetuation of various autoimmune
phenomena including neuroinflammation in the context of multiple sclerosis, colitis in inflammatory
bowel disease, nephritis in systemic lupus erythematosus, and insulitis in type 1 diabetes mellitus.
Owing to the widespread use of BPA and its effects on immune system dysregulation, a call
for careful assessment of patients’ risks and public health measures are needed to limit exposure
and subsequent deleterious effects. The purpose of this study is to explore the autoimmune triggering
mechanisms and present the current literature supporting the role of BPA in the pathogenesis of
autoimmune diseases.
Investigating Fill Factor Effect on Brillouin Zone of Metamaterial-Based 2D Photonic Crystal
Authors: Deyasi Arpan , Ghosh Ratul , Chakraborty Papri , Adhikary Anwesha , Sarkar Angsuman
Published: February 2021

:

Fill factor in the negative permittivity materials are tailored within the physically permissible
limits to characterize the Brillouin zone for two-dimensional crystal under the propagation of both s and
p-polarized waves. Two lowermost band-gaps are computed along with corresponding mid-band frequencies,
where the plane wave expansion method is invoked for computational purposes. The rectangular
geometrical shape is considered for the simulation, and all the results are calculated inside the ‘Γ’
point and ‘X’ point of the first Brillouin zone. Simulated findings depict monotonous variations of both
band-gap width as well as mid-band frequency for higher negative permittivity materials, when the
magnitude of fill factor is comparatively low, for both TE (Transverse Electric) and TM (Transverse
Magnetic) mode of propagations. Lower negative permittivity leads to random fluctuations, which
makes it unsuitable for photonic component design. Multiple forbidden regions may be observed for
some specific artificial materials which can be utilized in the antenna or multi-channel filter design in
higher THz region.

Aims:

The present paper aims to compute the shape of the first Brillouin zone from the fill factor for a
two-dimensional photonic crystal structure.

Background:

EBG (Electromagnetic Bandgap) of a photonic crystal plays a major role in determining
its candidature for optical applications, which is critically controlled by the fill factor. Therefore, it is
significant to investigate the effect of F.F on the wave propagation characteristics of 2D PhC(Twodimensional
photonic crystal).

Objective:

Investigation of metamaterial-based photonic crystal structure for electromagnetic band-gap
analysis in the desired spectrum of interest as a function of fill factor inside the first Brillouin zone.

Methods:

Maxwell’s equations are solved using the plane wave propagation method to solve the problem,
and simulation is carried out in MATLAB® software.

Result:

Both the first and second photonic band-gaps are simultaneously computed with a variation of
refractive index differences of the constituent materials as well as with the fill factors. Results are extremely
significant about the formation of narrowband and wideband filters on certain material combinations
and structural designs.

Conclusion:

Better tenability is observed for metamaterial structure compared to conventional positive
index materials, and fill factor has a great role in shaping the Brillouin zone and corresponding bandgap
width.
Chemical Constituents and Biological Activities of Cordia myxa L.: A Review
Authors: Singh Varinder , Sood Ankita , Pruthi Simran , Singh Manjinder , Saini Balraj , Singh Thakur Gurjeet , Kumar Amit
Published: February 2021

Background:

Cordia myxa L. (CM) is a valuable ethnomedicinal plant from Boraginaceae family. Traditionally, CM parts especially fruits and leaves are used in chest and urinary tract infections, diarrhoea, dysentery, tuberculosis, liver and spleen disorders, chronic fever, malaria etc.

Objective:

Despite of known importance and uses, CM has gained relatively less attention of researchers and concise reviews revealing the medicinal potential of CM are scanty. The present review summarizes the chemical constituents and biological activities of CM and aims to stimulate future research to develop it as a functional health food.

Results:

Analysis of literature on CM showed that its fruits are a rich source of nutrients and are frequently employed in wide ailments such as urinary and respiratory tract infections, chronic fever, liver disorders, asthma, used as anthelmintic, diuretic, expectorant and purgative. Scientific studies have shown the antidiabetic, analgesic, anti-inflammatory, anti-cancer, antioxidant, antiplasmodial, hepatoprotective, hypotensive, antiulcer and antimicrobial activities of CM. More than 45 compounds belonging to carbohydrates, steroids, carotenoids, phenols, flavonoids and alkaloids have been reported from various parts of CM.

Conclusion:

Systematic preclinical studies support the traditional claims of CM. The analysis of available literature showed that CM could be developed as a drug. Further, studies such as detailed pharmacological and toxicological evaluation, isolation of bioactive compounds, quantitative phytochemistry and structure activity relationship are scanty and thus, crucial to be addressed for uplifting the scientific value of this revered medicinal plant.
Applications of Covalent Triazine Polymers in Catalytic Organic Transformations
Authors: Raza A. Ahmed , Ravi Seenu , Tajudeen S. Syed , Sheriff A.K. Ibrahim
Published: February 2021

Among the porous organic polymers, Covalent Triazine Polymers (CTPs) have emerged
as an important class of materials with versatile applications such as energy storage and conversion,
gas adsorption and separation, photocatalysis and heterogeneous catalysis. Particularly, CTPs
have been often used as catalyst/catalyst support due to their excellent thermal and chemical stability,
as well as recyclability in catalytic reactions. Moreover, the expanding methods available for
the synthesis of CTPs, convenient functionalization and presence of nitrogen sites in the framework
make them a suitable candidate to develop catalysts for organic transformations. In this review,
the methods of synthesis, characterization of CTPs and mainly their applications as catalyst/
catalyst support in organic transformations are summarized.
Tackling COVID-19 Through Ayurveda: A Review on the Herbs of
Recommended Indian Remedies
Authors: Vegad Udaykumar G , Pandya Devang J
Published: February 2021

:

COVID-19 has rapidly spread across the globe and has been declared a pandemic. Presently, drugs or vaccines are unavailable, and patients are treated on symptom management basis. Traditional healthcare can contribute to prevent the infection in healthy individuals as well as in the treatment of infected patients. Ayurveda medicines become even more relevant as there is a descriptive illustration of causation and management of diseases similar to COVID-19 as Janapadodhwamsa. Meanwhile, Ministry of AYUSH, Govt. of India has recommended herbal remedies for prevention of COVID-19 infection. The remedies include 1. Herbal tea twice a day and 2. Golden milk for immunity boosting measures. Further, Steam inhalation and medicated honey is recommended for sore throat. In this review, we have tried to evaluate effectiveness of the recommended Indian remedies in prevention and treatment of COVID-19 conditions with available scientific literature. COVID-19, being primarily a respiratory disease, all 9 herbs of remedies have been selected for analysing their respiratory diseases related immunomodulatory and other activities, anti-viral, antibacterial activities as well as in silico effectiveness of constituents thereof against SARS-CoV-2 targets. The literature search was carried out in electronic databases namely PubMed, ScienceDirect, ACS Publications, Clinicaltrials.gov, Springer, and Google Scholar. The scientific evaluation revealed that the recommended Indian remedies might be useful in tackling COVID-19 situation, though scientific interventional studies are required to establish the claims.
Structure, Morphology Features and Photocatalytic Properties of α-Ag2WO4 Nanocrystals-modified Palygorskite Clay
Authors: Jucá Amanda Carolina Soares , Lopes Francisco Henrique Pereira , Silva-Júnior Herbert Vieira , Silva Lara Kelly Ribeiro , Longo Elson , Sczancoski Júlio César , Cavalcante Laecio S.
Published: February 2021

Aims:

In the present study, we investigate the photocatalytic properties of α-Ag2WO4 nanocrystals-
modified Palygorskite (PAL) clay synthesized by the impregnation method. The PAL clay
was chemically purified and heat-treated (500 ºC for 2 h), which served as an excellent supporting
matrix for loading α-Ag2WO4 (α-AWO) nanocrystals.

Background:

Water contamination is one of the most serious problems affecting human health, ecosystem
survival, and the economic growth of societies. Industrial effluents, such as textile dyes, when
not treated and improperly discharged into water resources are considered the main cause of water
pollution. Thus the scientific community has been developing effective remediation technologies
based on advanced oxidative processes to reduce the harmful effects of these organic pollutants.

Objective:

This study aimed to improve the photocatalytic activity of PAL clay with α-AWO nanocrystals
to degradation of Rhodamine B (RhB) dye.

Methods:

We purify and heat-treated the PAL clay, synthesize nanocrystals ofα-AWO nanocrystals and modify PAL clay with 30% α-AWO nanocrystals by the impregnation method. The modified PAL clay was able to improve RhB dye degradation. The materials were characterized by XRD, RAMAN,FE-SEM, FT-IR, XRF, etc. The samples were used as photocatalysts under UV-C lamps for the degradation of RhB dye in order to analyze its catalytic performances.

Results:

The PAL clay modified with 30% α-AWO nanocrystals showed a catalytic efficiency of
79%, and degradation kinetics about 16 times higher when compared to PAL-500 only purified and
heat-treated at 500 ºC. In this way, this PAL-modified is an alternative as a low-cost photocatalyst for
the degradation of RhB dye.

Conclusion:

Ultraviolet-visible spectra revealed that our materials have optical band gap energies
controlled by indirect and direct electronic transitions and suitable to be activated under ultraviolet illumination.
The adequate amount (30 wt.%) of α-Ag2WO4 nanocrystals added to PAL brought significant
improvement in the photocatalytic activity for the degradation of rhodamine B. Finally, a photocatalytic
mechanism was proposed in detail.
A Hybrid Branch Prediction Approach For High-Performance Processors
Authors: Nain Sweety , Chaudhary Prachi
Published: February 2021

Background:

In a parallel processor, the pipeline cannot fetch the conditional
instructions with the next clock cycle, leading to a pipeline stall. Therefore, conditional
instructions create a problem in the pipeline because the proper path can only be known after the
branch execution. To accurately predict branches, a significant predictor is proposed for the
prediction of the conditional branch instruction.

Method:

In this paper, a single branch prediction and a correlation branch prediction scheme are
applied to the different trace files by using the concept of saturating counters. Further, a hybrid
branch prediction scheme is proposed, which uses both global and local branch information,
providing more accuracy than the single and correlation branch prediction schemes.

Results:

Firstly, a single branch prediction and correlation branch prediction technique are applied
to the trace files using saturating counters. By comparison, it can be observed that a correlation
branch prediction technique provides better results by enhancing the accuracy rate of 2.25% than
the simple branch prediction. Further, a hybrid branch prediction scheme is proposed, which uses
both global and local branch information, providing more accuracy than the single and correlation
branch prediction schemes. The results suggest that the proposed hybrid branch prediction schemes
provide an increased accuracy rate of 3.68% and 1.43% than single branch prediction and
correlation branch prediction.

Conclusion:

The proposed hybrid branch prediction scheme gives a lower misprediction rate and
higher accuracy rate than the simple branch prediction scheme and correlation branch prediction
scheme.
Proyectar la memoria. Criterios y estrategias para la intervención, restauración y gestión del patrimonio cultural iberoamericano
Authors: Castañeda López Carolina
Published: February 2021

El libro nace con la voluntad de dar difusión a los contenidos de los seminarios-taller Proyectar la memoria que vienen realizándose desde el año 2012 en la Escuela de Patrimonio Histórico del Instituto del Patrimonio Cultural de España en Nájera (La Rioja). El elocuente título que da nombre a estos encuentros resume su propósito principal: la conversación en torno a los modos y formas actuales de entender y plantear la intervención en el patrimonio cultural en Iberoamérica.
Variación en la estructura del bosque de Abies religiosa (Pinaceae), en diferentes condiciones de manejo y disturbio
Authors: Hernández-Álvarez Adriana Gisela , Reyes-Ortiz José Luis , Villanueva-Díaz José , Sánchez-González Arturo
Published: February 2021

Antecedentes y Objetivos: El bosque de Abies religiosa o bosque de oyamel se distribuye en parches aislados y sus áreas continuas más extensas se localizan en la Faja Volcánica Transmexicana. Diversos estudios aportan información sobre aspectos ecológicos y florísticos del bosque de oyamel en México. Sin embargo, aún es necesario responder cuestiones ecológicas básicas, que pueden ser útiles para proponer y establecer estrategias de manejo y conservación de este tipo de vegetación. Por esta razón, los objetivos de la presente investigación fueron: (1) estimar la variación en la estructura poblacional de Abies religiosa y (2) determinar la estructura y composición arbórea y arbustiva del bosque de oyamel bajo diferentes condiciones de manejo.
Métodos: El área de estudio incluyó cinco localidades con bosque de oyamel del estado de Hidalgo, México, con diferentes condiciones de manejo y altitud. En total se colocaron 25 parcelas de muestreo (0.01 ha cada una) para obtener datos estándar a nivel poblacional (altura, densidad, diámetro) y comunitario (densidad, área basal y frecuencia de las especies).
Resultados clave: Dentro de las cinco localidades, tres poblaciones de A. religiosa se clasificaron como dinámicas, por presentar predominio de individuos pequeños; las dos restantes fueron normales, con alto porcentaje de plantas de tamaño intermedio. A nivel de comunidad, se registraron 15 especies de árboles y 15 de arbustos. La estructura del bosque difirió entre localidades, en especial las más lejanas geográficamente, corroborando el papel del manejo del bosque y de las condiciones ambientales locales.
Conclusiones: Abies religiosa dominó el dosel en todas las localidades. Las características estructurales a nivel de población y comunidad difirieron entre sitios de muestreo probablemente a causa del manejo forestal y de las diferentes condiciones ambientales locales.
Memoria de llegadas e ingresos por turismo en Cuba en el lustro 2015-2019
Authors: Ayala Castro Héctor , Hernández Flores Yoan
Published: February 2021

Para los gestores de las actividades vinculadas al sector del turismo, las tareas de planificación cobran mayor importancia en un contexto donde crece la demanda y varían las necesidades de los consumidores, por lo que se deben contar con bases de datos que permitan realizar pronósticos futuros. Cuba no está ajena a esta tendencia, es por ello que, con el objetivo de analizar el comportamiento de las llegadas y los ingresos por turismo en el lustro 2015 – 2019, al destino, se realiza la presente investigación. Con la combinación de diferentes métodos teóricos y empíricos se realiza un estudio de estos indicadores comparándolos con periodos anteriores, y con los principales destinos del Caribe Insular. El principal método utilizado es el análisis documental, pues se consultan varias fuentes de información de Cuba y del resto del mundo, con el fin de homogenizar los datos presentados, en la mayor medida posible. Finalmente, se muestra un análisis detallado que permite establecer la evolución del sector del turismo en la isla en este lustro, a partir de los indicadores seleccionados. De igual forma se muestran los cambios en el período analizado, así como algunas de sus consecuencias, sentando las bases para futuros estudios.
Расчет резонансных состояний кулоновских акцепторов в бесщелевых полупроводниках
Authors: Жолудев М.С. , Румянцев В.В. , Морозов С.В.
Published: February 2021

Проведены расчеты волновых функций электрона в зоне проводимости бесщелевого полупроводника вблизи кулоновского акцептора. Использовалась модель Латтинжера в приближении сферической симметрии. Получена зависимость энергии резонансных состояний акцептора от отношения масс электронов и дырок. Ключевые слова: бесщелевой полупроводник, примесь, резонансные состояния, матрица рассеяния.
Исследование пространственного распределения люминесценции в диапазоне 0.44-0.75 мкм CVD-ZnSe, легированного алюминием и железом
Authors: Калинушкин В.П. , Гладилин А.А. , Уваров О.В. , Миронов С.А. , Ильичев Н.Н. , Студеникин М.И. , Чапнин В.А. , Тимофеева Н.А. , Гаврищук Е.М. , Родин С.А. , Иконников В.Б. , Новиков Г.Г.
Published: February 2021

Spatial distribution of luminescence characteristics of CVD-ZnSe doped with Aluminum and both Aluminum and Iron by thermal diffusion were studied. The diffusion method leads to formation of two areas in crystal volume: (1) area with high aluminum concentration in which the luminescence of defective-impurity centers (DICs) dominates and exciton luminescence is absent and (2) area with low aluminum concentration in which exciton luminescence dominates. The border of two areas recognized on luminescence map is sharp that not corresponded to diffusion nature. The result is explained by assuming the anomalous nature of aluminum diffusion, leading to a sharp change in the aluminum concentration at a certain distance from the doping surface. Method of aluminum doping process applied in present paper leaded to weakens of well-known luminescence suppression effect by iron ions in ZnSe.
Deep Learning Model for Real-Time Prediction of Intradialytic Hypotension
Authors: Lee Hojun , Yun Donghwan , Yoo Jayeon , Yoo Kiyoon , Kim Yong Chul , Kim Dong Ki , Oh Kook-Hwan , Joo Kwon Wook , Kim Yon Su , Kwak Nojun , Han Seung Seok
Published: February 2021

Background and objectives

Intradialytic hypotension has high clinical significance. However, predicting it using conventional statistical models may be difficult because several factors have interactive and complex effects on the risk. Herein, we applied a deep learning model (recurrent neural network) to predict the risk of intradialytic hypotension using a timestamp-bearing dataset.

Design, setting, participants, & measurements

We obtained 261,647 hemodialysis sessions with 1,600,531 independent timestamps (i.e., time-varying vital signs) and randomly divided them into training (70%), validation (5%), calibration (5%), and testing (20%) sets. Intradialytic hypotension was defined when nadir systolic BP was <90 mm Hg (termed intradialytic hypotension 1) or when a decrease in systolic BP ≥20 mm Hg and/or a decrease in mean arterial pressure ≥10 mm Hg on the basis of the initial BPs (termed intradialytic hypotension 2) or prediction time BPs (termed intradialytic hypotension 3) occurred within 1 hour. The area under the receiver operating characteristic curves, the area under the precision-recall curves, and F1 scores obtained using the recurrent neural network model were compared with those obtained using multilayer perceptron, Light Gradient Boosting Machine, and logistic regression models.

Results

The recurrent neural network model for predicting intradialytic hypotension 1 achieved an area under the receiver operating characteristic curve of 0.94 (95% confidence intervals, 0.94 to 0.94), which was higher than those obtained using the other models (P<0.001). The recurrent neural network model for predicting intradialytic hypotension 2 and intradialytic hypotension 3 achieved area under the receiver operating characteristic curves of 0.87 (interquartile range, 0.87–0.87) and 0.79 (interquartile range, 0.79–0.79), respectively, which were also higher than those obtained using the other models (P≤0.001). The area under the precision-recall curve and F1 score were higher using the recurrent neural network model than they were using the other models. The recurrent neural network models for intradialytic hypotension were highly calibrated.

Conclusions

Our deep learning model can be used to predict the real-time risk of intradialytic hypotension.