bluuebunny/crossref_metadata_2025 huggingface dataset:
EFEITO DA ESCÓRIA DE SIDERURGIA NOS ATRIBUTOS QUÍMICOS DE UM LATOSSOLO AMARELO DISTRÓFICO EM TERRA ALTA - PA
Authors: Do Nascimento Emerson Vinicius Silva , Brasil Edilson Carvalho , Silva George Rodrigues da
Published: December 2019

O objetivo deste trabalho foi avaliar a aplicação de escória de siderurgia em diferentes granulometrias e doses, observando seus efeitos em diferentes tempos de incubação, sobre as propriedades químicas de um Latossolo Amarelo distrófico, textura média. Utilizou- se um delineamento experimental em blocos casualizados, com três repetições, em esquema fatorial 4x3x8+2, sendo quatro granulometrias (material retido entre as peneiras ABNT 20 – 50; 50 – 100; 100 - 200 e < 200), três doses de escória (1,65, 3,81e 5,98 t ha-1) necessárias para elevação das saturações por bases a 40, 70 e 100%, respectivamente, oito períodos de incubação da escória (15, 30 45, 60, 90, 120, 240 e 360 dias) e mais dois tratamentos adicionais, um com calcário e outro sem calcário e escoria (testemunha). Para avaliação dos atributos químicos efetuaram-se coletas de amostras na profundidade de 0–20 cm em cada parcela sendo 12 simples para formar uma composta utilizando um trado do tipo sonda, aos 15, 30, 45, 60, 90, 120, 240 e 360 dias. As frações granulométricas mais finas (100 - 200 e <200) foram mais efetivas na modificação dos atributos químicos.  Os tratamentos com a escória apresentaram melhores resultados, em comparação aos tratamentos adicionais (calcário + testemunha) nos atributos químicos do solo.                                                                             PALAVRAS-CHAVE: Acidez do solo, Saturação por bases, Silicato, Nutrientes.
MATRIZ LÓGICA DO PROGRAMA MAIS GESTÃO: AS PRINCIPAIS DIFERENÇAS ENTRE AS QUATRO CHAMADAS PÚBLICAS DE ATER
Authors: Silva Junior Luiz Honorato da , Nascimento Fernanda Regina , Ávila Mário Lúcio de , Melo Daiane Ricarda de , Santos Neto Alberto Abadia dos
Published: December 2019

No ano de 2011, o Ministério do Desenvolvimento Agrário criou o Programa Mais Gestão que visava aperfeiçoar a gestão de Cooperativas e Organizações Econômicas ligadas à agricultura familiar. O objetivo final era o de melhorar a eficiência de tais organizações com o fito de se ter suas participações em políticas de compras governamentais como o PNAE, o PAA e o PNPB.O objetivo deste trabalho é o de apresentar e discutir por meio de uma matriz lógica genérica os pontos tangentes e divergentes das primeiras quatro chamadas deste programa. A principal conclusão que se chega é a de que a matriz revela as sutilezas que foram desenhadas nas quatro chamadas para garantir cobertura ampla sobre as organizações econômicas da agricultura familiar na quase totalidade do país.                                                                             PALAVRAS-CHAVE: Programa Mais Gestão, Matriz Lógica, Chamadas Públicas de ATER.
DESPERDÍCIO DE ALIMENTOS: O PESO DAS PERDAS PARA OS RECURSOS NATURAIS
Authors: Barrozo Vanessa Pinto , De Sousa Hortência Araújo , Santos Marco Aurélio Oliveira , De Almeida Léo César Parente , Weiss Carla
Published: December 2019

Não há solução simples para alimentar sustentavelmente nove bilhões de pessoas, especialmente quando se converge para o aumento dos padrões de consumo. Para se disponibilizar alimento ao alcance das pessoas, não basta apenas aumentar a produção global, mas garantir que chegue ao consumidor final sem demasiadas perdas. À vista disso, o artigo busca identificar e analisar quais os principais temas e direcionamentos abordados pelas agências nacionais e internacionais acerca da problemática dos desperdícios e seus impactos sobre os recursos naturais. Dessa forma, recorreu-se ao software Iramuteq como recurso e constatou-se que o desperdício alimentar está relacionado a vários fatores que ligam países a seu estágio de desenvolvimento. Assim, trata-se de elementos ligados desde a colheita até sua preparação, bem como a manipulação inapropriada, armazenamento e transportes impróprios, hábitos culturais e a própria forma inadequada de preparo dos alimentos.                                                                             PALAVRAS-CHAVE: Produção de Alimentos, Perdas, Nível de Desenvolvimento, Impactos Ambientais.
A POLÍTICA DE CONCESSÃO EM FLORESTAS PÚBLICAS NO ESTADO DO PARÁ: O CASO DA UNIDADE DE MANEJO FLORESTAL (UMF) III DA GLEBA ESTADUAL MAMURU ARAPIUNS
Authors: Pereira Luciana Di Paula , Vasconcellos Sobrinho Mario , Flores Maria do Socorro Almeida
Published: December 2019

A modalidade de uso dos recursos florestais denominada concessão florestal é a forma de gestão em que o Estado delega a um concessionário o direito de gerenciar a exploração de uma área de floresta de domínio público. O objetivo deste artigo é analisar a efetividade desse modelo de gestão a partir da análise de um caso específico de concessão florestal, particularmente o caso da Unidade de Manejo Florestal III (UMF III) da Gleba Estadual do Mamuru Arapiuns, localizada entre os municípios de Santarém, Juruti e Aveiro, no estado do Pará. A análise é realizada a partir dos dados públicos disponíveis em órgãos ambientais do estado e da federação. Toma-se como referência para análise da efetividade os critérios estabelecidos pelo próprio edital público de concessão florestal da UMF III de Gleba Estadual do Mamuru Arapiuns reorganizados nas dimensões econômico-sociais, ambientais e institucionais. O artigo demonstra que a concessão florestal é eficiente enquanto política pública e eficaz enquanto ferramenta de gestão, porém, não há clareza quanto a efetividade do uso dos recursos para o desenvolvimento das comunidades locais. Para tanto, este artigo usou como parâmetro de referência as disposições da Lei Federal Nº 11.284, a Lei de Gestão de Florestas Públicas (LGFP), aprovada em 2006, apoiado por Sano e Montenegro Filho (2013), que permite realizar avaliação preliminar acerca das definições de eficiência, eficácia e efetividade no que diz respeito a legislação em questão.                                                                             PALAVRAS-CHAVE: Concessão Florestal, Recurso Florestal; Política Pública, Comunidades Locais, Sustentabilidade.
TOXICOLOGICAL ASSESSMENT OF THE EXPOSURE TO SOME ARYLHETEROALKANECARBOXYLIC COMPOUNDS ON THE BODY
Authors: Gorokhova Larisa G. , Zhukova A. G. , Kizichenko N. V. , Kazitskaya A. S.
Published: December 2019

Introduction. One of the current medical and social problems is the intoxication of the body of workers that occurs during the production of medicines in chemical-pharmaceutical enterprises. In this regard, it is necessary to substantiate and develop a hygienic rationing of the content of harmful substances in the air of the working area. Materials and methods. Toxicity parameters (1-benzylindol-3-yl-thio) acetic acid (BTAA) and tris-(2-hydroxyethyl) ammonium-1-benzylindol-3-ylthioacetate (VM-7-02) were studied. Experimental studies were conducted on outbred rats and mice, rabbits and guinea pigs. Using standard physiological, biochemical, hematological and morphological parameters, the effect of the substance on the experimental animals was evaluated. The parameters of acute inhalation toxicity of substances were determined during the experiment in the chamber for inhalation primers using spectrophotometry to analyze the amount of the substance in the air of the chambers. Processing and interpretation of the information obtained was performed using the software package “Statistic 10.0”. Results. In terms of mean lethal doses (DL50), both xenobiotics can be classified as moderately hazardous substances of hazard class III, and there are no specific species and sex differences in the sensitivity of animals to the substances under study. Local skin reaction and signs of resorption of substances through intact skin are absent. The irritant effect on the mucous membranes of the eyes of tris-(2-hydroxyethyl) ammonium-1-benzylindol-3-ylthioacetate can be classified as weak. The ability to material accumulation in the body of the compound VM-7-02 is medium: the cumulation coefficient is 3.7. At BTAA cumulative abilities are even weaker - the coefficient is equal to 5.1. In the subacute experiment, they have a toxic effect mainly on the hepatorenal system. The threshold of acute inhalation action of BTAA is 100.7, VM-7-02-57.8 mg/m3. Conclusion. A tentative safe level of exposure to VM-7-02 in the air of the working area is recommended at 0.3 mg/m3, BTAA is recommended at 2.0 mg/m3. Compliance with this standard will minimize the risk to the health of workers.
CHANGE OF THE PROFILE OF EXPRESSION OF ADAPTIVE RESPONSE GENES IN TOXIC HEPATITIS OF DIFFERENT ETIOLOGY
Authors: Karimov Denis O. , Kutlina T. G. , Mukhammadiyeva G. F. , Valova Y. V. , Repina E. F. , Khusnutdinova N. Yu.
Published: December 2019

Introduction. In Russia, the problem of toxic hepatitis is of great importance and relevance. The etiology of toxic hepatitis (industrial toxicants, drugs, ethanol) and, as a consequence, pathogenesis may have significant differences at the molecular genetic level. The aim of the study was to analyze the expression of genes involved in the response to toxic liver damage of various etiologies. Material and methods. Toxic hepatitis was modulated in male albino mongrel rats weighing 180-200 grams assigned to four groups (control group, carbon tetrachloride, paracetamol, ethanol). After 24 and 72 hours of paracetamol administration, rats were anesthetized and the mRNA levels of the Chek1, Gclc, Gstm1, Gstp1, Gstt1, Nfe2l2, Nqo1, Ripk1 genes in the liver homogenate were examined. Results. As a result of the analysis of the genes expression studied, the expression profile was found TO be differed depending on the etiology of toxic hepatitis. With carbon tetrachloride poisoning, an increase in the expression of the Nqo1 genes (p = 0.001), Gstm1 (p = 0.037) and a decrease in the expression of the Nfe2l2 genes (p = 0.004), Ripk1 (p = 0.004) was observed. With the liver damage by paracetamol and its metabolites, opposite to the expression of the Gstm1 gene (p = 0.001) decreased, and the expression of the Nfe2l2 (p = 0.009), Gclc (p = 0.001), Chek1 (p = 0.011) genes increased. During alcohol intoxication, there were no statistically significant changes in the expression profiles of the genes studied. Conclusion. the results obtained may indicate the involvement of various molecular genetic mechanisms in the process of response to toxic liver damage, depending on the etiology.
THE ROLE OF INDUSTRIAL AEROSOLS IN THE DEVELOPMENT OF ALLERGIC RESPIRATORY DISEASES AND MEASURES TO REDUCE THEM
Authors: Volgareva Alfiya D. , Shaikhlislamova E. R. , Bakirov A. B. , Abdrakhmanova E. R. , Gimranova G. G. , Karimova L. K.
Published: December 2019

Introduction. Industrial aerosols remain one of the main sources of development of occupational respiratory diseases of allergic etiology, leading to the early and permanent disability of qualified industrial workers. Material and methods. A retrospective analysis of the prevalence of occupational diseases of the respiratory tract from exposure to industrial aerosols according to statistical records and the first time established occupational diseases registration logs in the clinic for the period from 2008 to 2017 was carried out. Results. According to the analysis of occupational respiratory diseases in the Republic of Bashkortostan and the sanitary and hygienic characteristics of working conditions, the development of occupational allergic diseases of the respiratory organs was established in 54% of cases to be associated with exposure to aerosols of complex chemical composition exceeding the maximum permissible concentrations. Discussion. The working conditions of employees in a number of industries are characterized by the predominant effect of industrial aerosols of complex composition influenced the formation of occupational allergic diseases of the respiratory system. Adverse microclimatic conditions at the workplace in combination with a chemical factor are aggravating factors. The largest number of cases of occupational respiratory diseases is registered in the manufacturing sectors of the economy, mining companies, and the construction industry. Conclusion. Based on the studies conducted, measures have been developed to reduce the levels of exposure to industrial aerosols and to maintain workers’ health.
Model of social intelligence development in senior preschoolers in the process of joint activity
Authors: Savenkova Tatiana , Karpova Svetlana
Published: December 2019

The focus of preschool education national system is on the positive socialization of the individual, the development of flexible social behavior skills in children, the basis of which is social intelligence. The development of the basic parameters of social intelligence (cognitive, emotional, behavioral) most successfully occurs in the process of joint activity of a child with peers and adults. Joint activity with peers creates the prerequisites for positive socialization, the formation of the foundations of collective relationships, the development of communicative abilities, the development of leadership qualities of the child, the improvement of children's cooperation, the overcoming of the egocentrism objectively characteristic of preschool children, expressed in the first attempts to act in the interests of other people. We propose a model for the social intelligence development in older preschoolers in the process of joint activities of various subject areas, which includes two parts: the first part reproduces the structural and functional relationships between the main components of the model and serves as a source for teachers to develop methodological tools for the development of social intelligence; the second part of the model reproduces the successive stages of the educational work of the teacher on the development of social intelligence in older preschoolers in the process of joint activity in the conditions of a preschool educational organization.
Formation of foreign language grammatical competence among high school students
Authors: Elovskaya Svetlana , Karandeeva Liudmila , Hausmann-Ushkova Nadezhda
Published: December 2019

We substantiate the need for the foreign language grammatical competence formation among high school students. We consider personal, meta-subject, subject results of mastering the main educational program “Foreign Language”, reflected in the Federal State Educational Standard of Secondary General Education, the European system of levels of foreign language proficiency. Based on the fact that the result of mastering the basic course of a foreign language is the achievement of a threshold level of proficiency in a foreign language, the main criteria (the speed of individual operations, the number of grammatical constructions used, variability, accuracy) and the levels of formation of foreign language grammatical competence among high school students were determined. We focus on a complex of grammar exercises and tasks aimed at the reproduction, combined with the substitution; the expansion of a speech sample, the transformation and the combination. The topic “Conditional sentences” was chosen for a more accurate description of the complex of exercises and tasks. It is one of the most difficult grammatical topics proposed for study at school. We prove that methodically competently organized work on the foreign language grammatical competence formation among high school students makes the process of teaching foreign language effective and creative.
Method of projects in contemporary primary school
Authors: Pervova Galina , Gutarin Maksim
Published: December 2019

The relevance of the study is determined by the circumstances that method of projects began to be actively introduced into Russian primary education of the twenty-first century, as evidenced by publications in professional scientific and methodological sources, in particular, in the journal “Elementary School”. However, the understanding of method continues, especially given the fact that in the Soviet school method was criticized and rejected. We associate the change in attitudes towards the method of projects in the pedagogical environment mainly with convergent and activity approaches to the use of methods in the system of national education, with the focus of contemporary methods on the child’s personality development. We reveal the essence of method and give classification of projects. We show how in project activities under the guidance of a teacher and younger students themselves acquire new knowledge and use already existing ideas about various phenomena of the surrounding world. We also show how project participants im-prove their communication (group work) and research (finding truth) skills, develop creative thinking, master the skills to learn and techniques of organizing their own activities, which is es-pecially important in contemporary conditions and that Federal State Educational Standard of Primary General Education and the Federal State Educational Standards of Higher Education require. We identify factors that hinder the effective implementation of project method. The use of the project method in education and upbringing is one of the important components of modern teacher’s professional competence. In this regard, we reveal the importance of mastering the method by future primary school teachers.
Materials on the history of military temple construction in the funds of the Russian State Historical Archive
Authors: Ivitskaya Anna
Published: December 2019

The study of materials on the history of military temple construction is particularly relevant today. Archival sources play a special role in the study of the history of military temples of Saint Petersburg of the 18th – early 20th centuries. Official documentary and records management materials on military temple construction were partially covered in the study of the military clergy, the history of urban development, and mostly did not become the subject of special research in Russian literature. The purpose of the study is to identify and study a complex of historical sources on the history of the military temples construction in the funds of the Russian State Historical Archive. The methodological basis of the study is based on the principles of objectivity, historicism, systematic scientific analysis based on the scientific method of cognition, includes general historical research methods, and the method of historical heuristics is applied. The study is devoted to the description of materials on the history of military temples construction stored in the funds of the Russian State Historical Archive (RSHA). We highlight types of documents, collections of funds are described. We note the importance of studying the complex of official and records management documentation on the history of military temple construction. We consider the importance of technical documentation, which allows to obtain information on the technical condition of military temples and to reveal the dynamics of their construction. We carry out the analysis of sacristan inventory list, giving an idea of specific liturgical objects stored in churches and cathedrals.
Social and pedagogical aspects of the formation of student potential as a personnel reserve
Authors: Prokhorova Oksana , Kulichenko Raisa , Romanina Larisa
Published: December 2019

We present the social and pedagogical aspects of the formation of student potential as a personnel reserve. We reveal the functions and applied tasks of the social and pedagogical activity of the formation of student potential as a personnel which includes diagnostic, organizing, educating, developing, correcting, forming, prognostic components. We distinguish several typologies of the personnel reserve according to the type of activity, the speed of replacing posts, and the level of preparedness of a strategic and operational reserve. We study the student potential as a personnel reserve through an analysis of public opinion among full-time students of higher and secondary specialized educational institutions of Moscow and Tambov. The survey involved 220 full-time students. In addition to the survey, students were interviewed by the heads of various structural divisions and firms in order to find out their opinions on student employment and the formation of student potential as a personnel reserve. We indicate that in the process of formation of the personnel reserve a number of interrelated stages are distinguished: social and psychological study, selection of psychodiagnostic methods, psychodiagnostics and social and psychological prognosis.
Time and word in social and cultural space of the modernity
Authors: Ivanov Anatoly I.
Published: December 2019

Referring to the past era often intends to show the social and political system and, accordingly, focus is on the opinion of philosophers, sociologists, political scientists, etc. In this case, often on the sidelines is a person, his feelings, and attitude. This is evident in the attitude to the recent Soviet past of our country. In this regard, along with the coverage of the problem of time fixation in the artistic consciousness, we analyze the spiritual life of the transitional period, the main feature of which is the contradictory assessment of the 70-year history of the USSR. And it is not only about the nihilistic attitude, in the simplified denial of the Soviet experience, but also on ignoring the spiritual quest, the history of the formation of images and meanings inherent in our nation. The past time is not only economics and ideology, it is also artistic culture. Nihilistic atti-tude to the Soviet era is the way to oblivion of a huge cultural layer. It is an axiom which for some reason needs to be proved again and again. The social and cultural approach to the understanding of the past and present time has a greater tolerance in judgments and allows to fill the gaps in the public consciousness, to present spiritual life in diversity and uniqueness. The works of words, screen masters, sociologists conclusions contribute to the understanding of the recent past and the rapidly changing reality of the transition time.
Personal library as a reflection of the life and work history of A.V. Vysheslavtsev
Authors: Patrina Lyudmila N. , Sabetova Marina V.
Published: December 2019

We analyze A.V. Vysheslavtsev life history and creativity, and consider the importance of his personal library for professional pursuits and artistic hobbies. It is shown that reading played an important role in the upbringing of aesthetic taste and love of the beautiful in the Vysheslavtsev family. The estate library of the family estate Volkhonshchina accumulated a huge number of publications in Russian and foreign languages. Great importance in replenishing the rare foreign books collection played A.V. Vysheslavtsev’s uncle, who bought literature in the course of his foreign trips. On the basis of biographical research, the circumstances of the appearance of “Essays with quill and pencil out of circumnavigation of the world” we reveal their artistic and scientific value. We study the reasons of A.V. Vysheslavtsev’s foreign travels, and give the review of the books bought abroad. The analysis of the thematic composition of the library shows the diversity of readers’ interests of its owners. There were books on the history of European, Byzantine and Russian art. Collected for several decades, this collection can act as one of the elements of knowledge transfer to the Russian province. On the basis of studying foreign books A.V. Vysheslavtsev built scientific activity, prepared a number of serious studies on the Western art history. The heritage of A.V. Vysheslavtsev, without a doubt, has important historical, cultural and local history significance, reveals the creative laboratory of one of the most famous art critics of Russia of the 19th century.
Pós-humanismo da multidão em Antonio Negri
Authors: Pirola Émerson dos Santos
Published: December 2019

Após as críticas anti-humanistas estruturalistas e pós-estruturalistas à noção moderna de Sujeito, definido por sua identidade e interioridade transhistóricas – seja no recurso ao cogito, à razão, à consciência ou mesma à intersubjetividade e ao trabalho –, o marxismo se viu diante da exigência de enfrentar novamente um problema que sempre o perseguiu: como conceber um sujeito político de classe que se desvencilhe da carga metafísica própria das concepções modernas sobre o Sujeito. Mesmo que inconscientemente os diversos marxismos sempre trouxeram à contrabando a problemática do sujeito, visto que sua insistência em uma conceitualização de classe social leva a algo como um sujeito coletivo de lutas ou político. Com a crítica anti-humanista abriu-se caminho para uma construção teórica sobre a relação entre natureza e cultura, sujeito e objeto, humano e máquina que vai além dos limites estabelecidos pela filosofia moderna. Esse campo de estudos pode ser denominado genericamente de pós-humanismo, e é caracterizado por borrar as fronteiras citadas, levando a uma crítica mesma dessas separações. O dispositivo teórico marxista singular de Antonio Negri propõe uma conceituação de classe social e de sujeito/subjetividade classista que, além de partir das críticas anti-humanistas à metafísica do Sujeito, efetua uma composição entre o marxismo e as pautas propriamente pós-humanistas, chegando, com os conceitos de multidão e de comum, a uma concepção de sujeito classista que rompe com as barreiras do Sujeito moderno e institui uma espécie de humanismo depois da “morte do Homem”.
Cidades criativas e suas unidades de informação
Authors: Cativelli Adriana Stefani , Teixeira Clarissa Stefani
Published: December 2019

As cidades criativas são regiões que concentram pessoas e lugares com um objetivo em comum: fazer dele um lugar melhor para se viver por meio de diferentes conexões e utilizando o melhor de cada indivíduo, a criatividade. Florianópolis, por ser uma ilha, onde não podem-se instalar indústrias devido à limitação de espaço, destaca-se no mundo do empreendedorismo e consolida-se como polo de inovação tecnológica. O Centro Sapiens ao tomar conhecimento de exemplos internacionais avista na região leste do centro de Florianópolis, a oportunidade de transformação da região. O perímetro possui diferentes tipos de instituição, dentre elas as unidades de informação. Neste contexto, tem-se como objetivo mapear as unidades de informação que estão localizadas no Distrito Criativo de Florianópolis e construir a Rota das Unidades de Informação. A justifica baseia-se na premissa de que para se construir um ambiente criativo é necessário entrar em contato com fontes informacionais que ligam o passado ao presente, assim como divulgar esses espaços. Para mapeamento e criação da rota foi utilizado o Google My Maps. A rota reuniu 16 unidades de informação, os acervos contêm obras raras, históricas, especializadas, literatura, entre outros; e 87,5% permitem consulta aos seus acervos. Acredita-se que o convite aos gestores das unidades de informação para integrar o grupo de parceiros do Centro Sapiens possibilitará que os mesmos conheçam o projeto e passem a se sentir incluídos como agentes de transformação do local. Além de conhecerem seus colegas e buscar a conexão entre as unidades por um bem comum.
Gestão de dados de pesquisa
Authors: Estevão Janete Saldanha Bach , Arns Elaine Mandelli , Strauhs Faimara do Rocio
Published: December 2019

A Ciência Aberta tem constituído uma nova abordagem para o processo de geração de conhecimento científico, com base na forma colaborativa que a produção científica tem sido criada e comunicada. Os tradicionais resultados de pesquisa como artigos, dissertações e teses, ainda que disponíveis em acesso aberto podem ser comparados à uma caixa-preta, de acordo com a perspectiva da Teoria Ator-Rede (TAR), constituindo o resultado acabado da análise de um determinado pesquisador ou grupo de pesquisadores. Este artigo, eminentemente bibliográfico a partir de descritores, utiliza a pesquisa bibliográfica e bibliométrica como métodos de tratamento dos dados, seguido de revisão sistemática da literatura. O objetivo busca evidenciar como a disponibilidade dos dados de pesquisa interfere no processo de geração e de comunicação científica. Para tal utiliza-se das concepções da TAR na identificação do papel dos dados de pesquisa dentro de uma rede, composta por elementos humanos e não humanos. Como resultados, demonstra-se a partir do ciclo de vida dos dados de pesquisa, de que forma a disponibilidade destes produz novos recursos de informação, viabilizada pela retroalimentação da atividade científica.
Arthroscopic Treatment of Collapsed Subchondral Fatigue Fracture in the Femoral Head of a Young Military Recruit at a 5-Year Follow-Up
Authors: Kim Chul-Ho , Moon Jun-Ki , Yoon Jae Youn , Yoon Pil Whan
Published: December 2019

Case:

A 20-year-old military recruit presented with pain in his left hip. He was referred by the military hospital for osteonecrosis of the femoral head in both hip joints. Plain radiographs and magnetic resonance imaging showed a marked collapse in the left femoral head; however, the patient was diagnosed as having subchondral fatigue fractures of the femoral head (SFFFH) after a thorough review of previous sequential images. Arthroscopic debridement and labral repair were performed. At 3 years after surgery, the patient was symptom-free and second-look hip arthroscopy revealed the articular defect filling with fibrocartilage on the femoral head.

Conclusion:

In a young patient, hip arthroscopy can be a successful joint preserving treatment option even for collapsed SFFFH.
Canteras locales y rocas ornamentales empleadas en la arquitectura y epigrafía de Labitolosa (Conventus Caesaraugustanus, provincia Hispania citerior)
Authors: CISNEROS MIGUEL , GISBERT JOSEP
Published: December 2019

Los edificios públicos de Labitolosa fueron objeto de un importante proceso de monumentalización en la segunda mitad del siglo I d. C. En este trabajo nos centramos en la identificación geológica de las rocas ornamentales usadas en la Curia y en las termas I. Los análisis realizados indican un empleo exclusivo de calizas hispanas: la denominada Santa Tecla y las explotadas en Aguinalíu, donde se han localizado frentes antiguos de cantería. También se abordan cuestiones relacionadas con el coste del revestimiento marmóreo de las termas,
Nuevos datos sobre la producción oleícola en Colonia Patricia: el asentamiento romano de La Arruzafa (Córdoba)
Authors: CLAPÉS SALMORAL RAFAEL , RUBIO VALVERDE MANUEL , CASTILLO PÉREZ DE SILES FÁTIMA
Published: December 2019

La excavación arqueológica que se llevó a cabo en un solar emplazado en los terrenos de la Arruzafa, al norte de Córdoba, permitió documentar una secuencia estratigráfica muy dilatada en el tiempo. De las diversas fases de ocupación, nos detendremos en las estructuras adscritas a época romana, que se han interpretado como un asentamiento compuesto por varias dependencias destinadas a la producción de aceite. Este complejo oleícola estuvo en funcionamiento entre la primera mitad del s.I d.C. y finales del s.II d.C..
Nuevas aportaciones sobre el arrabal emiral de Šaqunda. A propósito de los restos arqueológicos de Gitanos 8 (Córdoba)
Authors: PIÑERO PALACIOS JUAN MANUEL , RODRÍGUEZ PÉREZ RAMÓN
Published: December 2019

Durante la excavación arqueológica de calle Gitanos 8 (Córdoba) apareció un fragmento de cerámica con grafía árabe incisa. Este pequeño fragmento epigrafiado se localizó dentro del contexto histórico del arrabal emiral de Šaqunda y nos puede dar cierta idea acerca del grado de alfabetización e islamización de este populoso arrabal cordobés a lo largo del siglo VIII, antes de su posterior destrucción y abandono durante el famoso motín del arrabal, a inicios del siglo IX. A propósito de la presentación de este grafito, aprovechamos también para dar a conocer nuevos datos sobre los restos arqueológicos donde se encontraba enmarcada la pieza.
Borehole-image-log characterization of deltaic deposits from a behind-outcrop well: Opportunities and limitations
Authors: Wolpert Philipp J. , Poppelreiter Michael C.
Published: December 2019

Borehole imaging (BHI) is a fast and precise method for collecting subsurface data. Rock calibration may reduce uncertainties inherent in interpretations of BHI logs. However, only few data sets are published that link borehole image facies to core and outcrop facies of deltaic successions. The objective of this paper is to compare and contrast sedimentologic features as seen in BHI, core, and outcrop, using a structured and hierarchical workflow. The research will provide a global framework for the interpretation of borehole images in similar environments.

A shallow, behind outcrop, research well (“Mondot-1”) drilled in NW Spain, penetrated a 185.50 m (TVD) thick section of the deltaic Sobrarbe Formation. A Formation MicroImager (FMI) borehole image log and a comprehensive well log suite was acquired in the fully cored well. The Eocene Sobrarbe Formation consists mostly of siliciclastic and some carbonate facies. Rapid vertical and lateral facies changes over a few tens of meters are observed in outcrops of the Sobrarbe Formation. The cored part of the formation is composed of argillaceous sandstone and carbonate with few diagnostic sedimentary features that can be used to constrain a conceptual depositional model. To provide a sedimentologically sound interpretation of this FMI log, we focused on layers showing diagnostic sedimentary features. Subsequently, facies associations and stratigraphic sequences were interpreted. Each facies association contained sedimentologic tie points that anchored the interpretation with diagnostic features such as slumps.

This paper suggests interpreting BHI false-color images of deltaic successions using conceptual geologic constraints such as 1) depositional tie points, 2) genetically related facies associations, and 3) a hierarchical stratigraphic framework, to establish meaningful conceptual depositional models.
Comparative transcriptomic and metabolic analysis of wild and domesticated wheat genotypes reveals differences in chemical and physical defense responses against aphids
Authors: Batyrshina Zhaniya S , Yaakov Beery , Shavit Reut , Singh Anuradha , Tzin Vered
Published: December 2019

Background Young wheat plants are continuously exposed to herbivorous insect attack. To reduce insect damage and maintain their growth, plants evolved different defense mechanisms, including the biosynthesis of deterrent compounds named benzoxazinoids, and/or trichome formation that provides physical barriers. It is unclear whether both of these mechanisms are equally critical in providing an efficient defense for wheat seedlings against aphids—an economically costly pest in cereal production. Results: In this study, we compared the transcriptome, metabolome, benzoxazinoids, and trichome density of three selected wheat genotypes, with a focus on differences related to defense mechanisms. We chose diverse wheat genotypes: two tetraploid wheat genotypes, domesticated durum ‘Svevo’ and wild emmer ‘Zavitan,’ and one hexaploid bread wheat, ‘Chinese Spring.’ The full transcriptomic analysis revealed a major difference between the three genotypes, while the clustering of significantly different genes suggested a higher similarity between the two domesticated wheats than between either and the wild wheat. A pathway enrichment analysis indicated that the genes associated with primary metabolism, as well as the pathways associated with defense such as phytohormones and specialized metabolites, were different between the three genotypes. Measurement of benzoxazinoid levels at the three time points (11, 15, and 18 days after germination) revealed high levels in the two domesticated genotypes, while in wild emmer wheat, they were below detection level. In contrast to the benzoxazinoid levels, the trichome density was dramatically higher in the wild emmer than in the domesticated wheat. Lastly, we tested the bird cherry-oat aphid’s ( Rhopalosiphum padi ) performance and found that Chinese Spring is more resistant than the tetraploid genotypes. Conclusions: Our results show that benzoxazinoids play a more significant defensive role than trichomes. Differences between the abundance of defense mechanisms in the wild and domesticated plants were observed in which wild emmer possesses high physical defenses while the domesticated wheat genotypes have high chemical defenses. These findings provide new insights into the defense adaptations of wheat plants against aphids.
Ultrasound assessment of central venous pressure: A systematic review and meta-analysis
Authors: Deschamps Jean , Lipes Jed , Weinstock Andrew , Jayaraman Dev , Rudski Lawrence , Afilalo Jonathan
Published: December 2019

Background Ultrasound is increasingly relied upon to estimate central venous pressure (CVP) in the echocardiography lab and using point-of-care systems in the intensive care unit and the emergency department. However, there is uncertainty regarding the diagnostic accuracy of ultrasound-based parameters as reported in diverse studies.Methods A systematic review was performed by searching MEDLINE, EMBASE, and the Cochrane Database for studies evaluating ultrasound-based indicators of filling pressures in relation to catheterization-based CVP. Studies were screened for predefined inclusion criteria and rated for quality by duplicate observers. Standardized correlation coefficients for each ultrasound-based indicator were meta-analyzed using a random effects model.Results 3949 articles were screened and 64 met the criteria for inclusion. Inferior vena cava (IVC) diameter was assessed in 34 study measures and the pooled standardized correlation with invasive CVP was 0.74 (95% CI 0.63 to 0.84). IVC collapsibility was assessed in 20 study measures and the pooled standardized correlation with invasive CVP was -0.57 (95% CI -0.70 to -0.44). Tricuspid E/Ep was assessed in 6 study measures and the pooled standardized correlation with invasive CVP was 0.59 (95% CI 0.26 to 0.93). IVC parameters but not E/Ep remained correlated with CVP in mechanically ventilated patients, including cardiac surgery patients. Results were similar in studies featuring non-traditional users and cardiac specialists.Conclusions Echocardiographic IVC diameter, collapsibility, and tricuspid E/Ep ratio are significantly correlated with invasive CVP, albeit with important heterogeneity between studies. Most of these indicators are equally valid when applied in ventilated patients and by non-traditional users.
Carotid artery ultrasound for evaluating the degree of stenosis and plaque composition in patients with coronary heart disease
Authors: Zhu Ye , You Jia , Xu Chao , Gu Xiang
Published: December 2019

Background: Early screening, diagnosis, risk assessment, and intervention of intima-media thickness (IMT) and carotid plaques is critical for assessing the risk of coronary heart disease (CHD). The current study aimed to assess carotid IMT and atherosclerotic plaque composition in patients with CHD by carotid artery ultrasound and to determine the associations of various factors with CHD. Methods: 480 patients with suspected CHD underwent a duplex ultrasound of the carotid arteries and coronary angiography or coronary CT. Then, the patients were investigated and evaluated to identify both personal and medical histories of clinical evaluations, and divided into the CHD (n=325) and control (n=155) groups based on clinical symptoms and vessel lesions. Associations of clinical characteristics with ischemic lesions determined by coronary angiography or CT were examined. Screening by B-mode carotid artery ultrasonography was performed the morning after admission prior to any treatment, coronary angiography or CT. Results: Cardiac diagnostic testing was performed in 134 subjects by CT coronary angiography, while the remaining 346 patients underwent coronary angiography. Carotid plaques were mainly distributed in the common carotid artery, with a significant difference between the CHD and control groups. Plaque incidence (80%) and IMT thickness (0.84±0.21) were significantly higher in the CHD group compared with control patients (P=8.92e-12 and P=0.012 respectively). The factors significantly associated with CHD were selected into the multivariate regression model. Male subject (OR=1.569, 95%CI 1.004-2.453; P=0.048) and plaque level (OR=0.457, 95%CI 0.210-0.993; P=0.048) were significant for CHD occurrence. The carotid plaque performed significantly better than IMT and the Framingham CHD risk score for predicting CHD risk (DeLong's correlated AUC test P=5.84e-4 and P=2.52e-5, respectively). Conclusions: The present study demonstrated that carotid artery ultrasound could be an effective method for early detection of atherosclerosis, which would help prevent CHD in asymptomatic patients with advanced atherosclerosis of the carotid artery. Incorporating carotid artery ultrasound plaque composition into screen practice may perform significantly better than the Framingham CHD risk factors for predicting CHD risk.
Prevalence and factors associated with meconium stained amniotic fluid in a tertiary hospital, Northwest Ethiopia: A cross sectional study
Authors: Abate Enyew , Alamirew Kassahun , Admassu Eleni , Derbie Awoke
Published: December 2019

Background Meconium is a green viscous fluid and its passage normally occurs within the first 24-48 hours after birth. However, fetuses could pass meconium before or during labor and mostly intrauterine passage was found to be associated with different feto-maternal stress factors resulting in increased risk of perinatal morbidity and mortality. In Ethiopia little is known about the proportion and associated factors for meconium stained amniotic fluid (MSAF). The aim of the study was to assess the proportion and associated factors of MSAF in women who came for labor and delivery service in a tertiary hospital in Ethiopia.Methods A cross sectional study was conducted from 1st June to 31 August, 2018 on 606 laboring mothers at Felege Hiwot Referral Hospital, northwest Ethiopia. Study participants were selected using a systematic random sampling technique. Data was collected using interviewer administered structured questionnaire. Data entry and analysis were made by using Epi-data v3.1 and SPSS v24, respectively. Both descriptive & analytical statistics were computed. Statistical significance was set at P < 0.05. Logistic regression was used to explore factors associated with MSAF.Results The proportion of MSAF was at 149 (24.6%) [95%CI: 21.3-28.2%]. Nonreassuring fetal heart rate pattern (AOR: 21.9,95% CI: 10.96-43.83), post term pregnancy (4.54,95% CI: 2.24-9.20), duration of labor more than 15 hours (AOR: 2.83,95% CI: 1.76-4.53), pregnancy induced hypertension (AOR: 2.43, 95% CI: 1.45-4.05), oligohydramnios (AOR: 2.53, 95% CI: 1.25-5.12) inter pregnancy interval less than 2 years (AOR: 2.24,95% CI: 1.12-4.51) and monthly family income less than 5000 Ethiopian Birr (185 United States Dollar) (AOR: 2.03, 95% CI:1.18-3.51) were significantly associated with MSAF.Conclusions The proportion of MSAF was at 24.6% which was higher than a previous study done in Ethiopia and elsewhere. Non-reassuring fetal heart rate pattern, post term pregnancy, duration of labor more than 15 hours, pregnancy induced hypertension, oligohydramnios, inter pregnancy interval less than 2 years and monthly family income less than 5000 Ethiopian Birr were factors associated with an increased risk for MSAF. Health professionals should assess laboring women for the presence of these factors and should stay alert to detect MSAF early and to act accordingly.
Per-head cost of patients responding to eltrombopag and rituximab in the treatment of primary immune thrombocytopenia in Spain.
Authors: Gonzalez-Porras José Ramón , Parrondo-García Francisco Javier , Anguita Eduardo
Published: December 2019

Background: Splenectomy, thrombopoietin receptor agonists (TPO-RAs) and rituximab are the second line treatments for steroid resistant adult primary immune thrombocytopenia (ITP). The last two are becoming the most widely used to avoid splenectomy adverse effects and inconveniences. However, the choice between rituximab and TPO-RAs is unclear. Therefore, the treatment cost may be of particular interest to prioritize the therapy option. Our aim is to know the cost per patient after a 6 months treatment in a European Health Service of rituximab compared to the TPO-RA eltrombopag. Methods: A 26-weeks decision tree model have been developed to assess the cost of treatment response of adult patients with chronic-refractory ITP to eltrombopag and rixutimab under the perspective of the Spanish National Health system. Effectiveness were obtained from literature and cost from the official rates. Costs were expressed in €(2018). Due to the short period of assessment, no discount rate was applied. Results: Average cost per patient after a 6 months treatment was similar for eltrombopag and rituximab, although the first one was slightly higher. However, the greater response rate of eltrombopag decreases the bleeding costs, resulting in a 29% higher cost with rituximab treatment. Eltrombopag cost is always lesser, except in the sensitivity analysis in which the patient received a daily dose of 75 mg of eltrombopag –a scenario where eltrombopag cost is 48€ higher than that of rituximab. Conclusions: The treatment cost of rituximab, including monitoring and bleeding costs is higher than eltrombopag, favouring the last one over rituximab treatment.
Clinical characteristics, antibiotic-resistant patterns and prognostic factors in cancer patients with nosocomial infections caused by extended-spectrum beta-lactamase-producing Escherichia coli: a retrospective study from 2013 to 2019
Authors: Jiang Ai-min , Shi Xin , Liu Na , Liang Xuan , Ruan Zhi-Ping , Zheng Xiao-Qiang , Fu Xiao , Tian Tao , Yao Yu
Published: December 2019

Background: Nosocomial infections due to Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) is increasing worldwide. This study aimed to describe the clinical characteristics, antibiotic-resistant patterns, and prognostic factors associated with nosocomial infections caused by ESBL-PE in cancer patients. Methods: This retrospectively analyzed patients with nosocomial infections caused by E. coli from August 2013 to May 2019 and was conducted to investigate the risk factors, clinical features, outcomes, and antibiotic-resistant patterns of these infections. Results: Of the 1008 nosocomial infection episodes, 265 patients suffered from infections with E. coli, and 155 episodes were caused by ESBL-PE. A multivariate analysis showed that the length of antibiotics treatment more than 6.93 days was an independent risk factor for nosocomial infections in cancer patients caused by ESBL-PE. ECOG performance status score more than 2, presence of respiratory tract infection, septic shock, lymphocytopenia, and hypoproteinemia were independent risk factors for 30-day mortality in cancer patients caused by ESBL-PE. Antimicrobial susceptibility showed that the isolated ESBL-PE were highly resistant to aztreonam and third-generation cephalosporins. Conclusions: The length of antibiotics treatment more than 6.93 days increased the risk ratio for ESBL-PE caused nosocomial infections. However, there was no significant difference in the prognoses of patients with ESBL-PE and non-ESBL-PE caused nosocomial infections. ECOG performance status score more than 2, presence of respiratory tract infection, septic shock, lymphocytopenia, and hypoproteinemia were independent risk factors for 30-day mortality in cancer patients with nosocomial infections caused by E. coli. The isolated ESBL-PE were highly resistant to aztreonam and third-generation cephalosporins.