bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of linguistic transformations in the translation of instructions for medical use from English into Russian (based on the instructions for the use of the immunomodulators Keytruda and Zelboraf)
Authors: Amirova Oksana Georgievna
Published: September 2023

The aim of the research is to describe the most characteristic lexical transformations used in the process of translating texts of instructions for medical use from English into Russian. The study is novel in that it is the first to analyze the transformations of lexical units involving the material of the instructions for the use of such modern immunomodulators as Keytruda and Zelboraf. The empirical study of the original instructions in English and their translations into Russian revealed the most frequent models of lexical transformations that ensure adequate perception of semantic information by the ultimate user of the corresponding drug. The research findings showed that the names of the drugs and active substances are subjected to transcription and transliteration; particularization is employed due to the need to clarify the area of denotation of English verbs of broad semantics; generalization is explained by the tendency to use generalized nouns (medication, medicinal product). Addition of lexemes is directly related to grammatical transformations at the morphological and syntactic levels; omission of lexemes is dictated by the phenomenon of couplets and the tendency to use clichéd phrases; meaning extension is chosen due to causal relationships between the lexemes of the original language and the target language.
DEVELOPING AN ALGORITHM FOR OPERATING THE HARDWARE MODULE OF THE AUTOMATION SYSTEM FOR DEPARTMENTAL PETROL STATIONS
Authors: Onufrieva Tat'yana , Razumov Vladislav , Borsuk Natal'ya
Published: September 2023

The issue of developing an algorithm for operating the hardware module of the departmental petrol station automa-tion system is considered. The paper gives the development features related to the system hardware implementation, which accounts and controls fuel consumption, analyses fuel level in the tank, provides service only to the authorised users, and also allows controlling the system remotely. The hardware part is implemented as a control terminal. The authors present the main stages of the algorithm development, including the system structure examination, the criteria development, the control scheme determination, the algorithm for operating the petrol station terminal, regulated by the operating mode cycle, taking into account the functional state of the system parameters. When developing the al-gorithm, the structural implementation features of the hardware module are taken into account, the parameters for using the GSM network, the freeRTOS operating system are determined, and the online payment card structure in the MIFARE card format is developed. A development peculiarity is that the developed algorithm for the terminal opera-tion can be adapted to the structure of any automated filling system without modifications.
FEDERAL AUTHORITIES’ INFORMATION SPACE MANAGEMENT SYSTEM
Authors: Labuz Ol'ga , Averchenkov Andrey , Izvol'skiy Aleksey
Published: September 2023

The professional activity of the federal authorities’ press services on forming and restoring the information space of the economic sphere is considered from the viewpoint of the management system of organisational systems. For the first time the authors have made an attempt to build and describe a universal model of the information space management system based on the management theory and the system approach. The system participants are determined, the mechanism of creating and coordinating informational events, as information units, are traced step by step. The authors review various definitions of the “information space” concept
CHRNA5 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that cholinergic receptor nicotinic alpha 5 subunit, encoded by CHRNA5, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. CHRNA5 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of CHRNA5 in primary tumors was correlated with patient distant metastasis-free survival. Modulation of CHRNA5 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Big Data Revolution: Transforming Information into Knowledge
Authors: Milson Smith , Oroy Kurez
Published: September 2023

Big Data Revolution: Transforming Information into Knowledge
PKM is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that pyruvate kinase, muscle, encoded by PKM, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. PKM mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of PKM in primary tumors was not correlated with patient survival. Modulation of PKM expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
CHRNA3 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that cholinergic receptor nicotinic alpha 3 subunit, encoded by CHRNA3, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. CHRNA3 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of CHRNA3 in primary tumors was correlated with patient distant metastasis-free and recurrence-free survival. Modulation of CHRNA3 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
MTCH2 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that mitochondrial carrier 2, encoded by MTCH2, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. MTCH2 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of MTCH2 in primary tumors was correlated with overall, distant metastasis-free and recurrence-free survival. Modulation of MTCH2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
NXPH4 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: September 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that neurexophilin 4, encoded by NXPH4, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. NXPH4 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of NXPH4 in primary tumors was correlated with overall and distant metastasis-free survival. Modulation of NXPH4 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
"Yeah, this graph doesn’t show that": Analysis of Online Engagement with Misleading Data Visualizations
Authors: Lisnic Maxim , Lex Alexander , Kogan Marina
Published: September 2023

Attempting to make sense of a phenomenon or crisis, social media users often share data visualizations and interpretations that can be erroneous or misleading. Prior work has studied how data visualizations can mislead, but do misleading visualizations reach a broad social media audience? And if so, do users amplify or challenge misleading interpretations? To answer these questions, we conducted a mixed-methods analysis of the public's engagement with data visualization posts about COVID-19 on Twitter. Compared to posts with accurate visual insights, our results show that posts with misleading visualizations garner more replies in which the audiences point out nuanced fallacies and caveats in data interpretations. Based on the results of our thematic analysis of engagement, we identify and discuss important opportunities and limitations to effectively leveraging crowdsourced assessments to address data-driven misinformation.
MENGUNGKAP PERILAKU BIAYA ADAT DUAN LOLAT PADA KEGIATAN ADAT ORANG MENINGGAL MASYARAKAT TANIMBAR DI DESA WOWONDA, KECAMATAN TANIMBAR SELATAN, KABUPATEN KEPULAUAN TANIMBAR
Authors: FENANLAMPIR KRISPINA
Published: September 2023

ABSTRAK Jenis Penelitian yang digunakan dalam penulisan ini adalah penelitian kualitatif dimana menepelitian ini di lakukan dengan pendekatan etnografi untuk mempelajari budaya dan perilaku biaya adat dengan kaitanya dengan akuntansi biaya.Tujuan penulisan ini adalah Mengungkap Perilaku Biaya Adat Duan Lolat pada Kegiatan Adat Orang Meninggal Masyarakat Tanimbar di desa Wowonda, lokasi penelitian adalah Masyarakat Tanimbar di Desa Wowonda Kecamtan Tanimbar Selatan, Kabupaten Kepulauan Tanimbar, intrumen dala penelitian ini adalah peneliti itu sendiri, teknik pengumpulan data yang digunakan dalam penelitian ini adalah wawancara, observasi, studi pustaka dan dukumentasi, teknik analisis data dalam penelitian ini adalah dengan menggunakan metode kualitatif Miles dan Huberman dengan teknik analisis Pengumpulan Data, (2) Reduksi Data, (3) Displai Data, (4) Verifikasi atau mengambil kesimpulan.
MEMBENTUK PEMIMPIN YANG BERKARAKTER KRISTUS
Authors: Tamelan Dewi Anjelina
Published: September 2023

Pemimpin adalah mempengaruhi orang lain untuk bekerja sama dalam mencapai tujuan yang ingin dicapai, pemimpin pada umumnya mementingkan diri mereka sendiri dibanding orang-orang yang dipimpin. maka dari penelitian ini dapat kita lihat bagaimana menjadi seorang pemimpin yang menjadi teladan atau memiliki karakter seperti Kristus, Dalam ingin menjadi pemimpin yang berkarakter Kristus, hal-hal yang perlu diperhatikan yaitu melakukan makna-makan dari kepemimpinan yang berkarakter Kristus dan kewajiban-kewajiban yang harus dimiliki oleh seorang pemimpin dan meneladani kepemimpinan Yesus kristus. Dalam penelitian ini menggunakan metode penelitian kepustakaan\literatur. Penelitian ini bertujuan untuk bagaimana menjadi pemimpin yang berkarakter Kristus. Dan penulisan ini menggunakan metode penelitian kepustakaan. . metode kepustakaan adalah metode yang menggunakan sumber kepustakaan berupa buku dan juga sumber lainnya yang berupa jurnal sesuai dengan topik yang dikaji.
How am I going and where to next? Elaborated online feedback improves university students’ self-regulated learning and performance
Authors: Theobald Maria , Bellhäuser Henrik
Published: September 2023

The goal of this study was to examine the effects of daily, adaptive feedback on self- regulated learning, motivation, and achievement. University students (N = 257) participated in an experimental field study with an intensive longitudinal design (daily assessment over 30 days). The experiment included a between-subject and a within-subject manipulation. The target of the feedback intervention was varied between subjects: Students either received (1) feedback on metacognitive aspects, (2) feedback on motivational aspects, (3) feedback on metacognitive and motivational aspects, (4) or no feedback. Within the three feedback groups, we additionally varied feedback content from day to day within-subjects. Students either received (1) informative feedback on self-regulated learning (2) directive feedback including only a strategy suggestion, (3) transformative feedback including feedback on self-regulated learning and a strategy suggestion, (4) or – on some days – no feedback. Results revealed that informative, directive, and transformative informative feedback reduced students’ procrastination and improved daily self-monitoring, adherence to time schedules, and goal achievement compared to receiving no feedback. Informative and transformative feedback additionally improved planning strategies and concentration. Motivation and self-efficacy were unaffected by any kind of feedback. The positive effects of the intervention were most pronounced when students received feedback on metacognitive and motivational aspects. Moreover, students in the feedback groups achieved better grades in the examinations compared students in the control group. Together, results indicate that the feedback intervention effectively improved students’ self-regulated learning and achievement. We discuss differential effectiveness of the feedback depending on feedback content.
Examining the neural basis of unitization: A review
Authors: Dennis Nancy , Carpenter Catherine M , Becker Alexa
Published: September 2023

Associative memory refers to the ability to form and remember associations between individual pieces of information rather than memory for a single object or word. Encoding associations in memory tends to be a more difficult task than item encoding as associative memory requires encoding multiple items as well as the specific links amongst the items. Associative memory has been shown to require cortical medial temporal lobe (MTL) engagement, to process context and item information, respectively, in addition to hippocampal engagement that is needed for the binding of distinct information. The need to engage greater and more disparate neural resources in order to execute associative encoding tasks often comes at a cost with respect to memory success, notably, there is poorer associative memory compared to item memory performance. Accordingly, researchers have worked to identify interventions and strategies aimed at reducing the effort and neural resources required for successful associative memory processing. One such means of support is the concept of unitization. Unitization has traditionally been defined as the process by which two or more discrete items are processed, or encoded, such that they are perceived as a single ensemble. The current review will explore the neural research on unitization while taking into account the behavioral benefits that accompany the process.
Mind the gap! Unmet time schedules predict university students’ negative affect during the examination phase
Authors: Theobald Maria , Bellhäuser Henrik
Published: September 2023

The goal of this study was to investigate the dynamic interplay of affect and time investment during exam preparation using daily learning diaries. University students (N = 56) reported a simultaneous increase in negative affect as well as intended and actual time investment over the course of the survey period (30 days). Cramming of study time partially accounted for the increase in negative affect. More planning strategies were associated with lower negative and more positive affect. Unmet time schedules predicted higher negative and lower positive affect. Results further revealed compensatory feedback loops: higher negative affect in the evening predicted higher intended time investment on the next morning, but without improvements in planning strategies. Results suggest that unmet time schedules could contribute to the increase in negative affect during exam preparation. Interventions should promote students’ planning to reduce the difference between intended and actual time investment.
Masculinity and the Questions of "Is" and "Ought": Revisiting the Definition of the Notion of Masculinity Itself
Authors: Arandjelović Ognjen
Published: September 2023

The Oxford English Dictionary (OED) lists 1571 as the year of the first recorded use of the English word ‘masculinity’; the Ancient Greek ανδρεια (andreia), usually translated as ‘courage’, was also used to refer to manliness. The notion of manliness or masculinity is undoubtedly older still. Yet, despite this seeming familiarity, not only is the notion proving to be highly elusive, its understanding by the society being in a constant flux, but also one which is at the root of bitter division and confrontation, and which has tangible and far-reaching real-world effects. At the same time, while masculinity has been attracting an increasing amount of attention in academia, the large body of published work seldom goes to the very foundations of the issue, failing to explicitly and with clarity reach a consensus as to how masculinity ought to be understood. Herein I critique the leading contemporary thought, showing it to be poorly conceived and confounded, and often lacking in substance which would raise it to the level of the actionable and constructive. Hence, I propose an alternative view which is void of the observed deficiencies, and discuss how its adoption would facilitate a conciliation between the currently warring factions, focusing everybody’s efforts on addressing the actual ethical, deconfounded of specious distractions.
What do people want from a welfare system? Conjoint survey evidence from UK adults
Authors: Nettle Daniel , Chrisp Joe , Johnson Elliott Aidan , Johnson Matthew Thomas
Published: September 2023

What do people want from a welfare system? Previous research has suggested a list of desiderata, such as that the system: reduces poverty; reduces inequality; improves mental and physical health; costs little; and rewards only the deserving. How do these different features trade off against one another to determine overall desirability? We conducted a conjoint survey experiment with 800 UK-resident adults, presenting them with hypothetical welfare schemes that varied on a large number of attributes. The strongest driver of choice was the effect on poverty: people were more likely to choose a scheme the more it reduced poverty. Respondents were prepared to trade off their preference for lower income taxes: even for centre-right voters, some income tax rises would be acceptable in exchange for sufficiently large reductions in poverty. Taxes on wealth and carbon emissions were positively valued. Respondents paid some attention to the effects of schemes on inequality and health. Preferences over institutional design features to do with deservingness, such as means testing, conditionality and universality, were weak. Heterogeneity in preferences by age and political orientation were present but modest. We discuss the findings with respect to the envelope of welfare systems that would be publicly acceptable.
Diagnostic and therapeutic dilemma due to new pattern electrocardiographic change in myocardial infarction: a case report from a remote island
Authors: Rana Ramesh , Najme Mohamed Shaneez , Gunaseelan  , Ara Jubida Gulshan , Shrestha Narottam , KC Bijaya
Published: September 2023

Acute myocardial infarction results due to acute disruption of coronary blood flow, commonly presented with chest pain. Electrocardiogram showing ST-segment elevation in consecutive leads is a classical ST-elevation myocardial infarction; however, atypical ST-segment elevation also can occur. We report an elderly lady who presented to the island health centre with intractable central chest pain. Electrocardiogram showed ST-segment elevation in V1 and aVR; whereas ST-depression in V4-6. With primary management, she was referred to a regional hospital. Repeat electrocardiogram showed ST-segment elevation in V1, aVR, and III; whereas ST-depression in V4-6, aVL, and I. Therefore, considering Aslanger's pattern of ECG change myocardial infarction, she was referred to the cardiac centre where coronary angiography revealed severe diffuse triple vessel disease. Primary PCI was performed on the right coronary artery initially as it is the primary culprit vessel with stenosis of other vessels. Therefore, staged angioplasty was performed on the left coronary system. Uncommon and atypical electrocardiographic presentations may be encountered in daily practice, associated with severe multiple-vessel diseases. So, it can be challenging for a cardiologist as well during interventions.
Estudo filogenético do ácaro Allopsoroptoides galli Mironov (2013) e avaliação do processo de transmissão horizontal em galinhas engaioladas
Authors:   , Duarte Fernanda Calvo
Published: September 2023

O ácaro plumícola Allopsoroptoides galli Mironov (2013) é o primeiro psoropitídeo observado nas penas de aves da ordem Galliformes durante um surto ocorrido em 2010 (quando ainda este ácaro era uma espécie desconhecida) em galinhas poedeiras de uma instalação comercial no Estado de São Paulo. Os danos causados pelo parasitismo desse ácaro estão relacionados à piora da conversão alimentar e à redução na produção de ovos. Com o objetivo de aprimorar os conhecimentos básicos do ácaro A. galli, neste trabalho foi realizado um estudo analítico da transmissão horizontal do ácaro A. galli através de um experimento de intervenção entre uma população exposta e outra não exposta ao ácaro A. galli, além de análises filogenéticas com sequências dos genes 18S e 28S rRNA do ácaro A. galli obtidas neste trabalho, e depositadas no GenBank com os seguintes códigos de acesso: OK533677 e OK533676. O experimento para a avaliação da transmissão foi realizado nos meses de fevereiro e março de 2021 no Instituto Biológico de Bastos. Foi utilizado um total de 30 aves alojadas em 6 gaiolas. Em cada gaiola foram colocadas 4 aves não parasitadas pertencentes ao grupo N (negativo) e uma infestada com o ácaro A. galli pertencente ao grupo P (positivo).
Características da inserção dos bioinsumos para controle biológico no mercado fitossanitário brasileiro
Authors:   , Bortoloti Gillyene
Published: September 2023

O agronegócio brasileiro se destaca na economia nacional e posiciona o Brasil como potência agrícola e ambiental no mundo. A importância e a comercialização de produtos fitossanitários seguem acompanhadas do desenvolvimento da agropecuária e da evolução do entendimento da mudança tecnológica, dos ganhos em produtividade e aumento da oferta de alimentos, em propostas contidas na Revolução Verde, caracterizadas pelo domínio dos agrotóxicos. No Brasil, a construção do ambiente de desenvolvimento tecnológico dos bioinsumos é pautada por importantes iniciativas que tomam espaço no início dos anos 2000, especialmente, no recorte dos bioinsumos para controle biológico. Os bioinsumos enfrentam desafios envolvendo questões regulatórias, de incentivo as pesquisas para desenvolvimento dessas tecnologias, colocadas como nicho na construção de um novo regime tecnológico. Sendo assim, esta pesquisa tem por objetivo caracterizar a inserção dos bioinsumos para controle biológico na agricultura brasileira. Para tanto, foram discutidos os ordenamentos do marco regulatório fitossanitário brasileiro, as estruturas da oferta e de demanda dos bioinsumos para controle biológico, a partir de informações oficiais disponibilizadas pelo Ministério da Agricultura, Pecuária e Abastecimento (MAPA), do Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais (IBAMA), da Coordenadoria de Defesa Agropecuária (CDA) do Estado de São Paulo e da Agência de Defesa Agropecuária do Paraná (ADAPAR), assim como foram exploradas oportunidades e desafios para esses insumos agrícolas com apoio das opiniões de agentes atuantes com o tema (researchers, stakeholders e policymakers).
Seleção de populações de Amblyseius largoensis (Muma) (Acari: Phytoseiidae) para o controle biológico de Raoiella indica Hirst (Acari: Tenuipalpidae) em coqueiro
Authors:   , Figueiredo Elias Soares de
Published: September 2023

Cocos nucifera L. assume grande importância na agricultura brasileira. A cultura enfrenta vários problemas fitossanitários, destacando-se, entre estes, aqueles causados por ácaros fitófagos. Raoiella indica Hirst causa danos significativos em coqueiro, devido à dificuldade de controle com uso de acaricidas químicos. Neste sentido, o uso de inimigos naturais tem se mostrado uma estratégia mais favorável para o manejo de R. indica. Objetivou-se com este trabalho, avaliar o potencial de uso de diferentes populações de Amblyseius largoensis (Muma) no controle de R. indica e selecionar uma linhagem do ácaro predador para uso em programas de controle biológico do ácaro-praga. Foram avaliadas nove populações de A. largoensis, procedentes dos estados do Amazonas, Ceará, Pará, Maranhão, Mato Grosso, Minas Gerais, Sergipe, Rio Grande do Norte e Rio de Janeiro. A população que apresentou as maiores taxas de predação e oviposição foi coletada no estado de Sergipe. A população do estado do Para foi a que apresentou o pior desempenho, em termos de predação e oviposição. Com os resultados obtidos para as distintas populações de A. largoensis, foram selecionadas as quatro populações (SE, MA, MT, RJ) de melhor desempenho para o processo subsequente de seleção. Neste processo, consideraram-se os parâmetros de predação e oviposição. Foram realizados sete ciclos de seleção, com intensidade de seleção de aproximadamente 50%. A linhagem selecionada de A. largoensis apresentou as maiores taxas de predação de ovos (50,4%), de imaturos (larvas e ninfas) (37,8%) e de adultos (104%) de R. indica, quando comparado à média das populações de campo não selecionadas, procedentes das diferentes regiões brasileiras. O processo de seleção não se mostrou efetivo para o aumento da taxa de oviposição de A. largoensis. Foram conduzidos, também, estudos em condições de semi-campo, para avaliar o desempenho da linhagem selecionada e duas populações (procedentes de Sergipe e Pará) de A. largoensis no controle de R. indica em plantas de coqueiro. Foram observadas diferenças significativas entre os tratamentos, verificando-se as maiores infestações de R. indica sobre as plantas sem liberação de ácaros predadores (controle) e nas plantas que receberam a liberação de ácaros predadores da população procedente do estado do Pará. Os ácaros predadores da linhagem selecionada de A. largoensis e da população procedente do estado de Sergipe causaram reduções significativas nas densidades populacionais de R. indica quando liberados em plantas de coqueiro, podendo ser úteis em programas de controle biológico do ácaro-praga.
Monitoramento de agrotóxicos em solo de produção orgânica, convencional e hidropônica e correlação com o controle químico de hortaliças cultivadas em Ibiuna
Authors:   , Bezerra Marta Moitinho
Published: September 2023

O destino ambiental dos agrotóxicos tem sido estudado em ambientes aquáticos continentais, mas raramente em solos no Brasil. O objetivo deste trabalho foi avaliar as concentrações de resíduos de agrotóxicos na camada superior do solo em cultura de hortaliças, no município de Ibiúna, São Paulo. Coletas de amostras foram realizadas nas profundidades de 15 cm, em três áreas com plantação de hortaliças com diferentes tipos de manejo: orgânico, convencional e hidropônico. Na produção orgânica e convencional são realizadas rotações de cultura, e pousio das áreas. Foram coletadas amostras compostas durante dois anos. Resíduos de 40 agrotóxicos foram analisados através de cromatografia à gás com detector de massas e cromatografia líquida com detector UV. Foi detectado um total de 3 agrotóxicos, clorfenapir, difenoconazol e procimidona. Quando o cultivo foi manejado de forma orgânica não apresentou resíduos de agrotóxicos no solo. Baixas concentrações de resíduos de agrotóxicos no solo que pratica o manejo convencional demonstra que o agricultor está seguindo as boas práticas agrícolas. O sistema de cultivo hidropônico apesar de não utilizar o solo para produção apresentou uma combinação de até três agrotóxicos no solo abaixo e aos redores do sistema de produção. Não existe legislação com limites máximos de agrotóxicos estabelecidos para o solo no Brasil, entretanto a contaminação é uma preocupação devido à alta persistência de alguns princípios ativos no solo e sua toxicidade para organismos não alvo e seres humanos.
The concomitance of Gitelman syndrome with nephrocalcinosis in a case followed-up for primary biliary cirrhosis
Authors: Kırık Melya Pelin , Hüzmeli Can
Published: September 2023

Gitelman syndrome is a rare autosomal recessive renal tubular disease characterized by hypokalemia, metabolic alkalosis, and hypocalciuria. The syndrome develops as a result of various mutations in the SLC12A3 gene. This manuscript aims to highlight the association of Gitelman Syndrome with nephrocalcinosis in a 48-year-old female patient who presented with pain and cramps in the lower limbs.
Comparison of clinical characteristics and outcomes of acute kidney injury in the elderly and younger hospitalized patients
Authors: Yesilova A. , Toprak I.D. , Uzun Y.E. , Cengiz M. , Turkmen B.O. , Yavuzer H. , Kocak G.
Published: September 2023

Data regarding the epidemiology, causes, and outcomes of acute kidney injury (AKI) are limited, especially in the elderly population. We aimed to investigate the clinical characteristics and early outcomes of AKI and to compare them between elderly and young patients hospitalized in an internal medicine clinic.

Methods. This single-center retrospective study included patients with AKI who were hospitalized in a tertiary hospital. AKI was identified according to the Kidney Disease Improving Global Outcomes criteria. Sociodemographic, clinical, and laboratory data were recorded. Renal recovery, need for dialysis, and in-hospital mortality were compared between the elderly (>60 years) and younger (≤60 years) patients.

Results. A total of 454 patients (327 elderly and 127 younger) were included in the study. The frequency of AKI in hospitalized patients was 12%. The most common cause of AKI was prerenal (61%). Prerenal AKI due to absolute intravascular volume reduction was the most important cause in both groups. Compared with the elderly patients, younger patients exhibited an increased rate of renal AKI (23% vs. 39%, p=0.001) and an increased need for dialysis during hospitalization (21% vs. 31.5% p=0.027). The incidence of vasculitis and glomerulonephritis was higher in younger patients with renal AKI than in the elderly patients (12% vs. 1.3% for vasculitis and 24% vs. 4% for glomerulonephritis p=0.001). Twenty-four percent of patients required dialysis during hospital stay and 10% required dialysis at discharge. The overall in-hospital mortality was 6,4%. Considering the AKI pathophysiology, the highest mortality rate was observed in AKI patients with renal origin (3.5%). There were no significant differences between elderly and younger patients based on renal recovery (complete recovery, 41% vs. 50%; progression 59% vs. 50%, p=0,073), hospital mortality (5.5% vs. 6.7%, p=0.634), and the need for dialysis at discharge (14% vs. 8.8%, p=0.082).

Conclusions. In our study, we concluded that there was no significant difference between elderly and younger hospitalized patients according to the early outcomes of AKI. However, the younger patients had a higher rate of renal AKI with a more severe course.
Analysis of The Factors Affecting The Interest of Overseas Students In Choosing a Boarding House
Authors: Ristanti Nila Riska , Simanjorang Elida Florentina Sinaga , Limbong Christine Herawati
Published: September 2023

A boarding house is a place to live that is needed by overseas students. In choosing a boarding house there are several factors that are taken into account by students, including price, facilities, and location. The purpose of this study is to analyze how the influence of price, facilities, and location factors influence the interest of overseas students in choosing boarding houses. This research was conducted in Kec. Southern Region, Kab. Labuhanbatu using quantitative methods. Data was collected by distributing questionnaires to 74 overseas students living in boarding houses around the South Rantau sub-district. The results showed that there was a positive influence between price, facilities, and location on the interest of overseas students in choosing boarding houses by 63% while the remaining 37% were influenced by other factors not examined by researchers.
The Prevalence of Genetic Determinants of Antibiotic Resistance, which are of Particular Epidemiological Consequences, in the Microbiota of the Oropharyngeal Swabs in Patients with Cystic Fibrosis
Authors: Skachkova T. S. , Kniazeva E. V. , Goloveshkina E. N. , Tronza T. V. , Kondratyeva E. I. , Voronkova A. Y. , Akimkin V. G.
Published: September 2023

Relevance. Antibiotic resistance of microorganisms can contribute to the chronicity of the inflammatory process, lead to an increase in the cost of treating patients and make it difficult to eradicate the pathogen. Patients with cystic fibrosis constantly require medical supervision, regular visits to medical institutions, and therefore there is a high risk of infection with nosocomial antibiotic- resistant strains. In addition, the necessary intake of antibacterial drugs provides an advantage for the reproduction of resistant microorganisms.

Aim. Comparison of the frequency of detection of antibiotic resistance determinants in oropharyngeal swabs in children with cystic fibrosis and conditionally healthy children using molecular biological methods.

Materials and methods. A PCR study of oropharyngeal discharge from 100 children with cystic fibrosis and 100 children from the control (healthy comparison subject) group was performed. Genetic antibiotic resistance locus: metallo-b-lactamases of the VIM, IMP and NDM groups; carbapenemase genes of the KPC and OXA-48 groups; extended-spectrum beta-lactamase genes of the CTX-M group and the mecA gene were detected by polymerase chain reaction (PCR) with hybridization-fluorescence detection.

Results and discussion. As a result of the analysis, a statistically significant increase in the frequency of detection of genetic determinants of antibiotic resistance in the microbiota of the oropharyngeal discharge in children with cystic fibrosis was found compared with healthy children (p<0.001). The chances of detecting antibiotic resistance loci in the discharge of the oropharynx among children with cystic fibrosis are 38.5 times higher than among healthy children (95% CI: 5.1-289.5). In 28% of children with cystic fibrosis, DNA of the genetic determinants of antibiotic resistance was detected in the microbiome of the discharge of the oropharynx. A high percentage of the presence of genetic determinants of antibiotic resistance may be the reason for the ineffectiveness of antibiotic therapy.

Conclusion. Due to the high occurrence in the microbiome of the oropharyngeal discharge of patients with cystic fibrosis of genetic antibiotic resistance locus that are of particular clinical and/or epidemiological significance, and the high risk of the spread of antibiotic-resistant strains outside medical institutions, it is necessary to include this group of patients in regular epidemiological monitoring.
A Study of Modern Trends in Database and Data Repository Technologies as the Technological and Architectural Basis for the Creation of Software and Intelligent Systems by Means of Modern Programming Languages. Part 1
Authors: YERSHOVA O. , STAVYTSKYI О.
Published: September 2023

The article contains an analytical review of developments in database technologies, made on the basis of reports prepared by the results of eight meetings of database specialists held throughout 1988–2013. Objects of the analysis are most interesting predictions given in the reports: their realism, accuracy, pragmatism or, vice versa, utopianism or opportunism.   

The article consists of two parts.

Part 1 is devoted to analysis and evaluation of predictions made in the reports of the four earlier meetings held in 1988, 1990, 1995, and 1996. These predictions are about creation, development and uses of decision support systems, database appliances, graphic processing units, operating systems, interface for structured query language, database applications, information distribution, universal database management systems, query optimization criteria, intellectual analysis of database within database management systems. A detailed description of research themes in the field of databases, which got the priority status in that time, is given: recording and computation of data, security and confidentiality of data, replication and harmonization of data, structuring of data, intellectual analysis of data, data warehouses.   

Part 2 is devoted to an analytical review of the predictions contained in the reports on the meetings held in 1998, 2003, 2008, and 2013. The predictions are about self-adjustment of database systems, rethinking of the traditional database architecture as a result of new hardware capabilities. They make special emphasis on the feasibility of manipulations with structured and unstructured data within DSS architecture, support of Big Data technology, with outlining the themes of research aimed at implementation of its potential.
Peripheral Computations: The Basis for Data Processing in Internet of Things
Authors: YERSHOVA O. L. , TOMASHEVSKA Т. V.
Published: September 2023

Internet of Things (ІоТ) is a global mainstream trend of today, which determines the importance of studies dealing with problems related with data processing by use of ІоТ.  
A definition to the notion “Internet of Things” is given, with stressing that peripheral computing is a new trend for connected devices of IoT. The main applications of IoT are described. Peripheral computing is compared with cloud and fog computing. The need for peripheral computing in the conditions of “smart” life is demonstrated. Various forms of the launched peripheral computing infrastructure are discussed. The need for peripheral computing in the software based on IoT technology is justified. It is shown that IoT pushes up the demand for peripheral computing. Real examples of successful applications of peripheral computing and IoT across industries are shown.   
It is stressed that the strongest impediment for the massive dissemination of IoT is that its infrastructure involves infinite numbers of options for connection, which may be quite often fully incompatible with each other. It is argued that peripheral computing is needed to remove drawbacks in software design and services on the basis of cloud technologies with consideration to performance and normative requirements. The forms of peripheral computing infrastructure are shown and described: special local devices, localized or regional data processing centers. The purpose of IoT technology is mentioned, which is the collection of large scopes of data from great many censors and smart devices, to be employed for business performance enhancement. The main reasons for the necessity of peripheral computing in the software based on IoT technology are outlined: the need to increase the throughput, the possibility to minimize the delay in data transmission and processing, and normative requirements. The main advantages of digital technology introduction are highlighted: better comfort of clients, higher exploitation efficiency, creation of new income flows.
Transport modulus of in-pipe diagnostic robot
Authors:   Russian State Scientific Center for Robotics and Technical Cybernetics, Pryadko Aleksey , Pavlov Nikolay ,   Russian State Scientific Center for Robotics and Technical Cybernetics,   Saint Petersburg Electrotechical University «LETI», Popov Dmitrii ,   Russian State Scientific Center for Robotics and Technical Cybernetics, Korotkov Aleksey ,   Russian State Scientific Center for Robotics and Technical Cybernetics, Hokkonen Evgeniy ,   Russian State Scientific Center for Robotics and Technical Cybernetics, Volkov Vladislav ,   Russian State Scientific Center for Robotics and Technical Cybernetics, Filippov Danila ,   Russian State Scientific Center for Robotics and Technical Cybernetics, Kadrov Andrey ,   Kalashnikov Izhevsk State Technical University
Published: September 2023

The paper presents the transport modulus design of an in-pipe diagnostic robot. The transport module is based on two load-bearing platforms with three radially mounted support legs with independent drive wheel engines. The proposed design solves the problem of increasing the mobility of the robot through technical solutions that ensure operation in pipes of complex configurations and various diameters and increase the length of the section inspect-ed in one pass. The algorithm of operation of the transport module is described when it is brought into working po-sition, moves along the pipe, passes between pipes of different diameters, passes bends, inclined sections and adapters.
Impacto en la salud mental durante los primeros quince días de confinamiento por COVID-19 en Ecuador
Authors: Ochoa-Andrade Miguel , Recalde-Moreno Joao , Dueñas-Espín Iván , Basurto-Vera Leonardo , Orozco Fernanda , Álvarez Mayra , Sigchos Jorge , Zurita Heliana , Vizcaíno Ángel , Chancusig Alejandro , Pañega Mónica
Published: September 2023

Introducción. Durante la pandemia por COVID-19, varios países iniciaron confinamiento debido a la propagación viral en la población, con varias consecuencias mentales debido a esta medida. Objetivo. Determinar los niveles de ansiedad y depresión en el personal de salud y población general durante los primeros quince días del confinamiento por COVID-19 en el Ecuador. Metodología. Se realizó un estudio transversal analítico. El 10 de mayo de 2020 (quince primeros días de confinamiento por COVID-19), se aplicaron encuestas con base a cuestionarios validados de BAI y BECK, con previo consentimiento informado a 500 profesionales de la salud rural y a población general (126 familias), para determinación de ansiedad y depresión. Se recolectaron variables sociodemográficas, toda la información fue recopilada en Microsoft Excel 2019. Se analizaron variables cualitativas y cuantitativas, se realizó un análisis bivariado y multivariado, se compararon modelos parsimoniosos y saturados, mediante el test de verosimilitud. Resultados. Se recolectó información de 421 personas, predominó el género femenino, la ansiedad y depresión con mayor frecuencia en población general, se encontró ansiedad en el 28,59 % (n=117/421) y 27,77 % (n=103/421) depresión en la población, las personas de la región costa y oriente reportaron menor probabilidad de presentar depresión versus la región sierra. Conclusión. Se evidenció que la sintomatología para ansiedad fue más frecuente en hombres y la depresión en mujeres. Se logró determinar que el 3,8 % (n=16) y el 7,84 % (n=33) correspondieron a niveles de depresión y ansiedad grave respectivamente.
The cultural policy of Luiz Inacio Lula da Silva, 2003—2010
Authors: Konstantinova Natalia
Published: September 2023

The article is devoted to the cultural policy pursued by the Brazilian President Luiz Inacio Lula da Silva during his term in power from 2003 to 2010. This phenomenon is considered in chronological order - respectively, at the first and second stages of Lula's reign. A brief historical excursus is preliminarily given and those traditions that were laid down in this area at previous historical stages are succinctly characterized. A fundamentally different approach to cultural policy is emphasized, which was proclaimed one of the priority areas for the new president and his cabinet of ministers in line with the country's democratization processes. Particular attention is paid to the role of the Ministry of Culture in the implementation of those tasks and areas of activity that had to be solved within the framework of the new concept of cultural policy. formulated by the Head of State and Minister of Culture Gilberto Gil almost immediately after they took office. It characterizes both the significant successes achieved during the two mandates of Lula's rule of power, and the considerable problems that had to be faced on the way to the implementation of numerous plans and projects, as a result of which they were only partially implemented.
Taubat Dalam Perspektif Al-Qur’an
Authors: Rinalpi Rinalpi , Satriadi Inong
Published: September 2023

The main problem in this thesis is repentance in the perspective of the Qur'an (study of thematic interpretation). As for the purpose of this study based on the formulation of the problem above, namely To describe and analyze how the Qur'an views the commands of repentance, the reward for repentance, the conditions for receiving repentance, and the causes for repentance. Thematic or maudhu'i interpretation and analysis methods are used in this type of library research. Data processing is done by clarifying verses about repentance from the perspective of the Qur'an, studying thematic interpretations, then processing and exploring the interpretation by referring to the book of Tafsir Muyassar and presenting it in effective sentences. The results of research related to repentance are fourfold: first, the command to repent is in the plural form, which means that it must be done by all humans and the law becomes mandatory. Second, there are seven replies to repentance. Third, the conditions for acceptance of repentance are seven and must be met. Fourth, there are nine reasons why a person repents.
Sprawozdanie z Międzynarodowej Konferencji Naukowej nt. Postępowanie administracyjne w Kościele. Lublin, dnia 6 czerwca 2011 roku
Authors: Lewicka Mariola
Published: September 2023

Problematyka prawa administracyjnego w Kościele była przedmiotem Międzynarodowej Konferencji Naukowej nt. Postępowanie administracyjne w Kościele, która odbyła się w Lublinie w dniu 6 czerwca 2011 r. Konferencję zorganizowali: Katedra Kościelnego Prawa Publicznego i Konstytucyjnego KUL, Stowarzyszenie Kanonistów Polskich, Instytut Prawa Kanonicznego KUL, Wydział Nauk Prawnych TN KUL, Polska Akademia Nauk Oddział w Lublinie.
Sprawozdanie z Walnego Zebrania Stowarzyszenia Kanonistów Polskich
Authors: Słowikowska Anna
Published: September 2023

Dnia 14 września 2011 r. w Auli Jana Pawła II Uniwersytetu Kardynała Stefana Wyszyńskiego w Warszawie odbyło się statutowe posiedzenie Walnego Zebrania Stowarzyszenia Kanonistów Polskich. Na przewodniczącego Walnego Zebrania wybrany został ks. prof. dr hab. Janusz Gręźlikowski, który przedstawił porządek obrad.