bluuebunny/crossref_metadata_2025 huggingface dataset:
AQP1-Containing Exosomes in Peritoneal Dialysis Effluent As Biomarker of Dialysis Efficiency
Authors: Corciulo Simone , Nicoletti Maria Celeste , Mastrofrancesco Lisa , Milano Serena , Mastrodonato Maria , Carmosino Monica , Gerbino Andrea , Corciulo Roberto , Russo Roberto , Svelto Maria , Gesualdo Loreto , Procino Giuseppe
Published: April 2019

The water channel Aquaporin 1 (AQP1) plays a fundamental role in water ultrafiltration during peritoneal dialysis (PD) and its reduced expression or function may be responsible for ultrafiltration failure (UFF). In humans, AQP1 is expressed in the endothelium of the peritoneal capillaries but its expression in mesothelial cells (MC) and its functional role in PD is still being debated. Here, we studied a cohort of 30 patients using PD in order to determine the presence of AQP1 in peritoneal biopsies, AQP1 release in the PD effluent through exosomes and the correlation of AQP1 abundance with the efficiency of peritoneal ultrafiltration. The experiments using immunofluorescence showed a strong expression of AQP1 in MCs. Immunoblotting analysis on vesicles isolated from PD effluents showed a consistent presence of AQP1, mesothelin and Alix and the absence of the CD31. Thus, this suggests that they have an exclusive mesothelial origin. The immunoTEM analysis showed a homogeneous population of nanovesicles and confirmed the immunoblotting results. Interestingly, the quantitative analysis by ELISA showed a positive correlation between AQP1 in the PD effluent and ultrafiltration (UF), free water transport (FWT) and Na-sieving. This evidence opens the discussion on the functional role of mesothelial AQP1 during PD and suggests that it may represent a potential non-invasive biomarker of peritoneal barrier integrity, with predictive potential of UFF in PD patients.
mTOR Signalling in Head and Neck Cancer: Heads Up
Authors: Tan Fiona H. , Bai Yuchen , Saintigny Pierre , Darido Charbel
Published: April 2019

The mammalian target of rapamycin (mTOR) signalling pathway is a central regulator of metabolism in all cells. It senses intracellular and extracellular signals and nutrient levels, and coordinates the metabolic requirements for cell growth, survival, and proliferation. Genetic alterations that deregulate mTOR signalling lead to metabolic reprogramming, resulting in the development of several cancers including those of the head and neck. Gain-of-function mutations in EGFR, PIK3CA, and HRAS, or loss-of-function in p53 and PTEN are often associated with mTOR hyperactivation, whereas mutations identified from The Cancer Genome Atlas (TCGA) dataset that potentially lead to aberrant mTOR signalling are found in the EIF4G1, PLD1, RAC1, and SZT2 genes. In this review, we discuss how these mutant genes could affect mTOR signalling and highlight their impact on metabolic processes, as well as suggest potential targets for therapeutic intervention, primarily in head and neck cancer.
Effect of Urea-Formaldehyde-Coated Epoxy Microcapsule Modification on Gloss, Toughness and Chromatic Distortion of Acrylic Copolymers Waterborne Coating
Authors: Yan Xiaoxing , Wang Lin , Qian Xingyu
Published: April 2019

The modification experiment of waterborne coating was carried out by adding microcapsules. The wall material of the microcapsule was urea-formaldehyde resin and the core material of the microcapsule was epoxy resin. Core material can improve the toughness of the coating and prevent the cracking of the coating. The influences of different contents of microcapsules and the order of adding microcapsules in the coating process on the properties of gloss, color difference and toughness were studied. The results showed that the gloss of the waterborne coating decreased with the increase of microcapsule content. The color difference of coating increased first and then decreased, and when the microcapsule content was 8.0%, the color difference was the largest. The toughness of the coatings also increased first and then decreased. When the content of the microcapsule was 10.0%, the toughness of the coating was significantly enhanced. When the microcapsules with a content of 10.0% were added to the waterborne coating, under the same process, the coating gloss of microcapsules added to the primer was relatively high, and the coating gloss was the highest when the coating process was three-layer primer and two-layer topcoat. The microcapsule had little effect on the color difference of coating in different coating processes. When the coating process was three-layer primer and three-layer topcoat, the coating toughness was the best when microcapsules were added to the topcoats. This study provides a basis for industrial application of waterborne coatings to enhance their toughness.
The Evaluation of Durability of Plasma-Sprayed Thermal Barrier Coatings with Double-layer Bond Coat
Authors: Li Xiao , Peng Xin-Yu , Dong Hui , Zhou Yong , Wang Tao , Ren Kang , Sun Liang
Published: April 2019

The durability of atmospheric plasma-sprayed thermal barrier coatings (APS TBCs) with a double-layer bond coat was evaluated via isothermal cycling tests under 1120 °C. The bond coat consisted of a porosity layer deposited on the substrate and an oxidation layer deposited on the porosity layer. Two types of double-layer bond coats with different thickness ratios of the porosity layer to the oxidation layer (type A: 1:2 and type B: 2:1, respectively) were prepared. The results show that the porosity layer was oxidation free, the oxidation layer included a fraction of well-distributed α-Al2O3. The coefficient of thermal expansion of the oxidation layer was about 11.2 × 10−6 K−1, which was rather lower than that of the porosity layer. Thus, the oxidation layer can be regards as a secondary bond coat between ceramic topcoat and traditional bond coat. The thermal cyclic lifetime of type A TBCs was about 60 cycles, which exceeded 1.2 times the durability of type B TBCs. The delamination cracks in both TBCs all propagated in the ceramic topcoat, which were all identical to those in traditional TBCs. Therefore, the design of the double-layer bond coat affected the stress level rather than the stress distribution in TBCs.
Proactive Release of Antimicrobial Essential Oil from a “Smart” Cotton Fabric
Authors: Štular Danaja , Šobak Matic , Mihelčič Mohor , Šest Ervin , German Ilić Ilija , Jerman Ivan , Simončič Barbara , Tomšič Brigita
Published: April 2019

Two temperature and pH responsive submicron hydrogels based on poly(N- methylenebisacrylamide), chitosan and β-cyclodextrines (PNCS/CD hydrogel) with varying poly(N-isopropylacrylamide) to chitosan ratios were synthesized according to a simplified procedure, reflecting improved stimuli responsive properties and excellent bio-barrier properties, granted by incorporated chitosan. Hydrogels were applied to cotton-cellulose fabric as active coatings. Subsequently, antimicrobially active savory essential oil (EO) was embedded into the hydrogels in order to develop temperature- and pH-responsive cotton-cellulose fabric with double antimicrobial activity, i.e., bio-barrier formation of chitosan along with the proactive release of savory EO at predetermined conditions. The influence of the hydrogels chemical composition on stimuli responsive and antibacterial properties were assessed. Both PNCS/CD hydrogels showed stimuli responsiveness along with controlled release of savory EO. The chemical composition of the hydrogels strongly influenced the size of the hydrogel particles, their temperature and pH responsiveness, and the bio-barrier forming activity. The increased concentration of chitosan resulted in superior overall stimuli responsiveness and excellent synergy between the antimicrobial activities of the hydrogel and released savory EO.
Quantized Alternate Current on Curved Graphene
Authors: Flouris Kyriakos , Succi Sauro , Herrmann Hans J.
Published: April 2019

Based on the numerical solution of the Quantum Lattice Boltzmann Method in curved space, we predicted the onset of a quantized alternating current on curved graphene sheets. This numerical prediction was verified analytically via a set of semi-classical equations that related the Berry curvature to real space curvature. The proposed quantized oscillating current on curved graphene could form the basis for the implementation of quantum information-processing algorithms.
High Stability LED-Pumped Nd:YVO4 Laser with a Cr:YAG for Passive Q-Switching
Authors: Xiao Hong , Zhao Tianzhuo , Ge Wenqi , Zhong Qixiu , Li Mingshan , Yu Jiaqi , Fan Zhongwei , Bian Shengwei , Chen Yanzhong
Published: April 2019

With improvements in light-emitting diode (LED) performance and a sharp decline in price, a light source with the irradiance of a laser and the cost of an LED is worthy of further study. We demonstrated a LED-pumped Nd:YVO4 laser in quasi-continuous-wave (QCW) and passively Q-switched (PQS) regime. With an incident pump energy of 6.28 mJ (150 μs pulses at 1 Hz), the Nd:YVO4 laser has an energy of 206 μJ at 1064 nm in the QCW regime. The optical conversion efficiency of the system is 4.1%, and the slope efficiency is 9.0%. A pulsed energy of 2.5 μJ was obtained with a duration of 897 ns (FWHM) in the PQS regime, which means the peak power is 2.79 W. The output energy stability is 97.54%.
Dual-Time-Point FDG Uptake Correlates with Prognostic Factors of Invasive Breast Cancer: Clinical Usefulness of Early Delayed Scanning
Authors: Lee Ji Young , Song Hee-Sung , Choi Jae Hyuck , Hyun Chang Lim
Published: April 2019

This study investigated correlations between fluorodeoxyglucose (FDG) uptake in tumors as assessed by modified dual-time-point (mDTP) FDG positron emission tomography/computed tomography (PET/CT) in invasive breast cancer (iBC) and several prognostic parameters. Thirty-two women who underwent mastectomies for iBC were retrospectively evaluated. mDTP scanning was performed using standard FDG PET/CT (PET1), followed by early delayed acquisition (PET2) without repositioning and additional CT scanning. Using maximal standardized uptake values on PET1 (SUV1) and PET2 (SUV2) in the primary breast tumor, the percentage changes between SUV1 and SUV2 (retention index, (RI)) were calculated. Prognostic parameters (e.g., tumor size and stage; number of metastatic lymph nodes; histologic grade; expression of estrogen receptor (ER), progesterone, epidermal growth factor receptor (HER-2), and p53; and the Ki-67 labeling index (LI)) were evaluated from the surgical specimens. PET2 scans were conducted 17.7 ± 1.5 min after PET1. RI values gradually increased as the histologic grade increased (p = 0.016), and were significantly higher when ER expression was absent (p = 0.023) and Ki-67 LI was high (p < 0.001). RI values also showed a moderately positive correlation with Ki-67 LI (r = 0.629; p < 0.001). RI correlated with well-known biologic prognostic factors of iBC and mDTP scanning, which could be used as a substitute for conventional DTP PET.
Transversely Compact Single-Ended and Balanced Bandpass Filters with Source–Load-Coupled Spurlines
Authors: Yan Fang , Huang Yong Mao , Huang Tao , Ding Shuai , Wang Kenian , Bozzi Maurizio
Published: April 2019

Multi-function wireless systems demand multi-channel transmit/receive (TR) modules, particularly as multiple functions are required to operate simultaneously. In each channel, passive components, including bandpass filters, must be compact, or at least transversely compact; thus, the entire circuitry of the channel will be slender, and consequently multiple channels can be parallel-arranged conveniently. In this work, single-ended and balanced bandpass filters for multi-channel applications are presented. As a unique resonator, the U-shaped stepped impedance resonator (USIR) can achieve size miniaturization compared with its corresponding uniform impedance resonator (UIR) counterpart. Hence, with the utilization of USIRs, the proposed bandpass filters are able to acquire compact transverse sizes. Moreover, by using the source–load coupling scheme, two transmission zeros (TZs) are respectively generated at the lower and upper sides of the passbands, which is useful for improvement of the selectivity performance. In addition, spurlines are introduced at the input and output ports to produce another TZ to further enhance the stopband performance, which cannot be acquired by the UIR or stepped impedance resonator (SIR). To verify the aforementioned idea, one single-ended and one balanced bandpass filter are implemented, with experimental results in good agreement with the corresponding simulations. Meanwhile, as compared with some similar works, the proposed balanced filter achieves compact transverse size, sharp selectivity skirt, and wide stopbands up to the fourth-order harmonic with suppression over 20 dB, which illustrates its suitability for differential signal transmission application in microwave circuits and systems.
Implementation of Pattern Recognition Algorithms in Processing Incomplete Wind Speed Data for Energy Assessment of Offshore Wind Turbines
Authors: Panapakidis Ioannis P. , Michailides Constantine , Angelides Demos C.
Published: April 2019

Offshore wind turbine (OWT) installations are continually expanding as they are considered an efficient mechanism for covering a part of the energy consumption requirements. The assessment of the energy potential of OWTs for specific offshore sites is the key factor that defines their successful implementation, commercialization and sustainability. The data used for this assessment mainly refer to wind speed measurements. However, the data may not present homogeneity due to incomplete or missing entries; this in turn, is attributed to failures of the measuring devices or other factors. This fact may lead to considerable limitations in the OWTs energy potential assessment. This paper presents two novel methodologies to handle the problem of incomplete and missing data. Computational intelligence algorithms are utilized for the filling of the incomplete and missing data in order to build complete wind speed series. Finally, the complete wind speed series are used for assessing the energy potential of an OWT in a specific offshore site. In many real-world metering systems, due to meter failures, incomplete and missing data are frequently observed, leading to the need for robust data handling. The novelty of the paper can be summarized in the following points: (i) a comparison of clustering algorithms for extracting typical wind speed curves is presented for the OWT related literature and (ii) two efficient novel methods for missing and incomplete data are proposed.
Evaluation of Cyclic Gas Injection in Enhanced Recovery from Unconventional Light Oil Reservoirs: Effect of Gas Type and Fracture Spacing
Authors: Assef Yasaman , Pereira Almao Pedro
Published: April 2019

Production from ultra-low permeability shale plays requires advanced technologies such as horizontal wells with multistage hydraulic fracturing treatment. In this study, a cyclic gas injection method with two pumping schedules is introduced as an enhanced oil recovery (EOR) method. Fracture spacing and type of injection gas in a horizontal well from the Bakken formation are analyzed through numerical simulations. The economic profitability and reservoir performance are also investigated. Rate transient analysis is used to anticipate hydraulic fracture and effective fracture permeability. Different fracture spacings are selected as the major determinant factor in generating an effective reservoir contact area. Compositional simulations are conducted to model incremental oil recovery after cyclic injection of three gases (ethane, CO2, and natural gas). Economic indicators of net present value (NPV), internal rate of return (IRR) and oil recovery factor are compared to determine the best alternative among the proposed investment scenarios. Current market and a certain time-frame (2015–2035) are used to assess the investment viability of unconventional oil plays. Cyclical injection of ethane and CO2, remarkably improved oil recovery from the Bakken example. Natural gas injection however, led to inferior results and in terms of investment, may not guarantee the long-term success. Some scenarios are identified as profitable for high oil-API but do not achieve positive outcomes from lower oil specific gravities. The results from this study highlight the impact of fracture spacing in incremental oil recovery. Producing a majority of the cumulative oil during the first years makes most of the scenarios viable only for short terms. To maintain the long-term cost-effectiveness, performing cyclic gas injection through hydraulic fractures is recommended. Cycle sizes directly impact the propagation of injectant and the extent of the drainage area. Increasing the number of fracking stages can be an alternative strategy to gas injection in reservoirs with lower oil-API.
The Influence of Power Quality Indices on Active Power Losses in a Local Distribution Grid
Authors: Otcenasova Alena , Bolf Andrej , Altus Juraj , Regula Michal
Published: April 2019

This paper deals with the topic of power quality in a local distribution grid. It is aimed to analyze the individual influences, which aggravate the power quality of the distribution grid. Based on the analysis, the most adverse effects were determined, and they were the voltage drops and supply voltage interruptions, supply voltage unbalance, load power factor, and also higher harmonics. These influences cause the technical losses in a distribution grid, which subsequently have a financial impact not only on the distribution, but also on the transmission of electricity. Only the load voltage unbalance, the load power factor, and the higher harmonics, which mainly cause the technical losses, were analyzed in this paper. The measurement of the influences of the adverse effects was performed on the model of a 22-kV distribution grid. The measurement was performed on the basis of three types of power line conductors and their different lengths, three types of active power consumption, and the different values of these adverse effects. According to this measurement, a simulation in program Matlab-Simulink was created. This simulation represented part of a 22-kV distribution grid, which was influenced by the abovementioned adverse effects. The results of the measurements were compared with the results of the simulation. Based on the evaluation of the technical losses from the measurement and the simulation, the financial losses during a certain period were calculated for the distribution system operators.
The Management of Compounds that Influence Human Health in Modern Winemaking from an HACCP Point of View
Authors: Benito Santiago
Published: April 2019

The undesirable effects of some hazardous compounds involved in the different steps of the winemaking process may pose health risks to consumers; hence, the importance of compliance with recent international food safety standards, including the Hazard Analysis and Critical Control Point (HACCP) standards. In recent years, there has been a rise in the development of new technologies in response to the hazardous effects of chemical compounds detected during the winemaking process, whether naturally produced or added during different winemaking processes. The main purpose was to reduce the levels of some compounds, such as biogenic amines, ethyl carbamate, ochratoxin A, and sulfur dioxide. These technological advances are currently considered a necessity, because they produce wines free of health-hazardous compounds and, most importantly, help in the management and prevention of health risks. This review shows how to prevent and control the most common potential health risks of wine using a HACCP methodology.
The RoboPol Program: Optical Polarimetric Monitoring of Blazars
Authors: Blinov Dmitry , Pavlidou Vasiliki
Published: April 2019

After three years of polarimetric monitoring of blazars, the RoboPol project has uncovered several key characteristics of polarimetric rotations in the optical for these most variable sources. The most important of these is that polarization properties of the synchrotron emission in the optical appear to be directly linked with gamma-ray activity. In this paper, we discuss the evidence for this connection, as well as the broader features of polarimetric behavior in blazars that are key in making progress with theoretical modeling of blazar emission.
Chia (Salvia hispanica L.) a Promising Alternative for Conventional and Gelled Emulsions: Technological and Lipid Structural Characteristics
Authors: Muñoz-González Irene , Merino-Álvarez Esther , Salvador Marina , Pintado Tatiana , Ruiz-Capillas Claudia , Jiménez-Colmenero Francisco , Herrero Ana M.
Published: April 2019

Chia (Salvia hispanica L.) is an oilseed plant which contains proteins of high biological value and other healthy components with interesting technological properties. For these reasons, chia could be a promising option for the formation and stabilization of oil-in-water emulsions. The aim of this study is to evaluate the potential of chia protein (from chia flour) in the formation of emulsions. To that end, composition and technological and structural properties determined by infrared spectroscopy were investigated in conventional (EC) and gelled (EGC) emulsions with chia and compared with their corresponding soy protein emulsions with the same protein content [conventional (ES) or gelled (EGS)] used as reference. All emulsions containing chia had better fat and water binding properties than those elaborated with soy protein isolate (SPI). The color of the emulsions varied significantly depending on whether the emulsions were made with chia or SPI. EGS and EGC exhibited the greatest (p < 0.05) penetration force values, being EGC the firmest (p < 0.05). Depending on the type of emulsion, Attenuated Total Reflectance (ATR)-FTIR Spectroscopy revealed differences in their lipid structure and interaction in terms of lipid acyl chain mobility (order/disorder) and emulsion droplet size. These structural characteristics could be related to the textural behavior of emulsions.
Generations Comparison: Father Role Representations in the 1980s and the New Millennium
Authors: Bosoni Maria Letizia , Mazzucchelli Sara
Published: April 2019

In the light of relevant and current debate on the changing role of fathers, this contribution is aimed at analysing the international literature on fatherhood, comparing two distinct periods of time, from the social, cultural and demographic point of view: the years 1980–1999 and the new millennium. This will contribute to identifying features of the fatherhood transformation in these two contexts, which in fact refer to two generations of fathers. The research questions to be answered are: Which aspects characterize the process of fatherhood transformation, in an intergenerational perspective? How are paternal childcare practices represented in different historical and social periods? An analysis of the academic publications on fathers in Scopus and Google Scholar will be conducted, in the two temporal periods indicated, using T-Lab software, in order to map fathers’ role representations.
DNA Authentication of St John’s Wort (Hypericum perforatum L.) Commercial Products Targeting the ITS Region
Authors: Howard Caroline , Hill Eleanor , Kreuzer Marco , Mali Purvi , Masiero Eva , Slater Adrian , Sgamma Tiziana
Published: April 2019

There is considerable potential for the use of DNA barcoding methods to authenticate raw medicinal plant materials, but their application to testing commercial products has been controversial. A simple PCR test targeting species-specific sequences within the nuclear ribosomal internal transcribed spacer (ITS) region was adapted to screen commercial products for the presence of Hypericum perforatum L. material. DNA differing widely in amount and extent of fragmentation was detected in a number of product types. Two assays were designed to further analyse this DNA using a curated database of selected Hypericum ITS sequences: A qPCR assay based on a species-specific primer pair spanning the ITS1 and ITS2 regions, using synthetic DNA reference standards for DNA quantitation and a Next Generation Sequencing (NGS) assay separately targeting the ITS1 and ITS2 regions. The ability of the assays to detect H. perforatum DNA sequences in processed medicines was investigated. Out of twenty different matrices tested, both assays detected H. perforatum DNA in five samples with more than 103 ITS copies µL−1 DNA extract, whilst the qPCR assay was also able to detect lower levels of DNA in two further samples. The NGS assay confirmed that H. perforatum was the major species in all five positive samples, though trace contaminants were also detected.
Adeno-Associated Viral Vectors as a Tool for Large Gene Delivery to the Retina
Authors: Trapani Ivana
Published: April 2019

Gene therapy using adeno-associated viral (AAV) vectors currently represents the most promising approach for the treatment of many inherited retinal diseases (IRDs), given AAV’s ability to efficiently deliver therapeutic genes to both photoreceptors and retinal pigment epithelium, and their excellent safety and efficacy profiles in humans. However, one of the main obstacles to widespread AAV application is their limited packaging capacity, which precludes their use from the treatment of IRDs which are caused by mutations in genes whose coding sequence exceeds 5 kb. Therefore, in recent years, considerable effort has been made to identify strategies to increase the transfer capacity of AAV vectors. This review will discuss these new developed strategies, highlighting the advancements as well as the limitations that the field has still to overcome to finally expand the applicability of AAV vectors to IRDs due to mutations in large genes.
Pacbio Sequencing Reveals Identical Organelle Genomes between American Cranberry (Vaccinium macrocarpon Ait.) and a Wild Relative
Authors: Diaz-Garcia Luis , Rodriguez-Bonilla Lorraine , Rohde Jessica , Smith Tyler , Zalapa Juan
Published: April 2019

Breeding efforts in the American cranberry (Vaccinium macrocarpon Ait.), a North American perennial fruit crop of great importance, have been hampered by the limited genetic and phenotypic variability observed among cultivars and experimental materials. Most of the cultivars commercially used by cranberry growers today were derived from a few wild accessions bred in the 1950s. In different crops, wild germplasm has been used as an important genetic resource to incorporate novel traits and increase the phenotypic diversity of breeding materials. Vaccinium microcarpum (Turcz. ex Rupr.) Schmalh. and V. oxycoccos L., two closely related species, may be cross-compatible with the American cranberry, and could be useful to improve fruit quality such as phytochemical content. Furthermore, given their northern distribution, they could also help develop cold hardy cultivars. Although these species have previously been analyzed in diversity studies, genomic characterization and comparative studies are still lacking. In this study, we sequenced and assembled the organelle genomes of the cultivated American cranberry and its wild relative, V. microcarpum. PacBio sequencing technology allowed us to assemble both mitochondrial and plastid genomes at very high coverage and in a single circular scaffold. A comparative analysis revealed that the mitochondrial genome sequences were identical between both species and that the plastids presented only two synonymous single nucleotide polymorphisms (SNPs). Moreover, the Illumina resequencing of additional accessions of V. microcarpum and V. oxycoccos revealed high genetic variation in both species. Based on these results, we provided a hypothesis involving the extension and dynamics of the last glaciation period in North America, and how this could have shaped the distribution and dispersal of V. microcarpum. Finally, we provided important data regarding the polyploid origin of V. oxycoccos.
Going Deeper into High and Low Phylogenetic Relationships of Protura
Authors: Carapelli Antonio , Bu Yun , Chen Wan-Jun , Nardi Francesco , Leo Chiara , Frati Francesco , Luan Yun-Xia
Published: April 2019

Proturans are small, wingless, soil-dwelling arthropods, generally associated with the early diversification of Hexapoda. Their bizarre morphology, together with conflicting results of molecular studies, has nevertheless made their classification ambiguous. Furthermore, their limited dispersal capability (due to the primarily absence of wings) and their euedaphic lifestyle have greatly complicated species-level identification. Mitochondrial and nuclear markers have been applied herein to investigate and summarize proturan systematics at different hierarchical levels. Two new mitochondrial genomes are described and included in a phylum-level phylogenetic analysis, but the position of Protura could not be resolved with confidence due to an accelerated rate of substitution and extensive gene rearrangements. Mitochondrial and nuclear loci were also applied in order to revise the intra-class systematics, recovering three proturan orders and most of the families/subfamilies included as monophyletic, with the exception of the subfamily Acerentominae. At the species level, most morphologically described species were confirmed using molecular markers, with some exceptions, and the advantages of including nuclear, as well as mitochondrial, markers and morphology are discussed. At all levels, an enlarged taxon sampling and the integration of data from different sources may be of significant help in solving open questions that still persist on the evolutionary history of Protura.
Home as Love: Transcending Positionality in Leila Aboulela’s The Translator
Authors: Zannoun Ghadir K.
Published: April 2019

Contrary to hegemonic Western representations of Muslim women as victims of Islam and Muslim men, Sudanese-Scottish Leila Aboulela’s The Translator depicts a Muslim woman, Sammar, whose sense of home and belonging is predicated on her romantic love for her late cousin and husband, Tarig. Therefore, after his death, she feels alienated from her home in Sudan and leaves for Aberdeen, Scotland, where she is ostracized because she is Muslim. While this Muslim identity proves indispensable for her survival and gradual healing, ultimate normalcy and belonging are restored when she reclaims the world of love and acceptance she has lost with Tarig’s death through a new relationship. The romantic love and the language she uses in this relationship allow Sammar to restore the sense of being and the belonging she had at home within the spaces she occupies in Aberdeen, ending her alienation and reclaiming her subjectivity. Using feminist theory and postcolonial theories of place and identity, as well as Lila Abu-Lughod’s notion of emotional discourse as a pragmatic act, this study investigates the novel’s depiction of place and identity as constructed entities embedded in emotion. This depiction, this study proposes, undermine various positionalities and binaries, such as self/other and east/west, allowing Aboulela to approach them more critically.
Technology to Support Aging in Place: Older Adults’ Perspectives
Authors: Wang Shengzhi , Bolling Khalisa , Mao Wenlin , Reichstadt Jennifer , Jeste Dilip , Kim Ho-Cheol , Nebeker Camille
Published: April 2019

The U.S. population over 65 years of age is increasing. Most older adults prefer to age in place, and technologies, including Internet of things (IoT), Ambient/Active Assisted Living (AAL) robots and other artificial intelligence (AI), can support independent living. However, a top-down design process creates mismatches between technologies and older adults’ needs. A user-centered design approach was used to identify older adults’ perspectives regarding AAL and AI technologies and gauge interest in participating in a co-design process. A survey was used to obtain demographic characteristics and assess privacy perspectives. A convenience sample of 31 retirement community residents participated in one of two 90-min focus group sessions. The semi-structured group interview solicited barriers and facilitators to technology adoption, privacy attitudes, and interest in project co-design participation to inform technology development. Focus group sessions were audiotaped and professionally transcribed. Transcripts were reviewed and coded to identify themes and patterns. Descriptive statistics were applied to the quantitative data. Identified barriers to technology use included low technology literacy, including lack of familiarity with terminology, and physical challenges, which can make adoption difficult. Facilitators included an eagerness to learn, interest in co-design, and a desire to understand and control their data. Most participants identified as privacy pragmatics and fundamentalists, indicating that privacy is important to older adults. At the same time, they also reported a willingness to contribute to the design of technologies that would facilitate aging independently. There is a need to increase technology literacy of older adults along with aging literacy of technologists.
Transport System Models and Big Data: Zoning and Graph Building with Traditional Surveys, FCD and GIS
Authors: Croce Antonello Ignazio , Musolino Giuseppe , Rindone Corrado , Vitetta Antonino
Published: April 2019

The paper deals with the integration of data provided from traditional transport surveys (small data) with big data, provided from Information and Communication Technology (ICT), in building Transport System Models (TSMs). Big data are used to observe historical mobility patterns and transport facilities and services, but they are not able to assess ex-ante effects of planned interventions and policies. To overcome these limitations, TSMs can be specified, calibrated and validated with small data, but they are expensive to obtain. The paper proposes a procedure to increase the benefits of TSMs’ building in forecasting capabilities, on one side; and limiting the costs connected to traditional surveys thanks to the availability of big data, on the other side. Small data (e.g., census data) are enriched with Floating Car Data (FCD). At the current stage, the procedure focuses on two specific elements of TSMs: zoning and graph building. These processes are both executed considering the estimated values of an intensity function of FCDs, consistently with traditional methods based on small data. The data-fusion of small and big data, operated with a Geographic Information System (GIS) tool, in a real extra-urban context is presented in order to validate the proposed procedure.
Structural Performance of Polyurethane Foam-Filled Building Composite Panels: A State-Of-The-Art
Authors: Samali Bijan , Nemati Saeed , Sharafi Pezhman , Tahmoorian Farzaneh , Sanati Farshad
Published: April 2019

Composite panels with polyurethane (PU) foam-core and facing materials, such as gypsum, engineered wood or some composite materials, are being used as structural members in building construction. This paper reviews and summarises major research developments, and provides an updated review of references on the structural performance of foam-filled building composite panels from 1998 to 2017. The review revealed that previous studies on the structural performance of foam-filled building composite panels could be categorised into five themes; namely, energy absorption and dynamic behaviour; bending and shear behaviour, edgewise and flatwise compressive/tensile behaviour; delamination/deboning issues; and finally some miscellaneous issues. These categories comprise approximately 30%, 40%, 11%, 11% and 8% of related studies over the last two decades, respectively. Also, over the past five years, the number of relevant studies has increased by ~400% relative to the previous similar periods, indicating the attention and focus of researchers to the importance of the structural performance of foam-filled composite panels.
Influence of Mixing Procedures, Rubber Treatment, and Fibre Additives on Rubcrete Performance
Authors: Youssf Osama , Hassanli Reza , Mills Julie , Skinner William , Ma Xing , Zhuge Yan , Roychand Rajeev , Gravina Rebecca
Published: April 2019

This research extensively investigates how to enhance the mechanical performance of Rubcrete, aiming to move this type of concrete from the laboratory research level to a more practical use by the concrete industry. The effects of many different mixing procedures, chemical pre-treatments on the rubber particles, and the use of fibre additives, have been investigated for their impact upon Rubcrete workability, compressive strength, tensile strength, and flexural strength. The mixing procedure variables included mixing time and mixing order. The rubber pre-treatments utilized chemicals such as Sodium Hydroxide (NaOH), Hydrogen Peroxide (H2O2), Sulphuric acid (H2SO4), Calcium Chloride (CaCl2), Potassium Permanganate (KMnO4), Sodium Bisulphite (NaHsO3), and Silane Coupling Agent. Soaking rubber particles in tap water, or running them through water before mixing, were also tried as a pre-treatment of rubber particles. In addition, the effects of fibre additives such as steel fibres, polypropylene fibres, and rubber fibres, were assessed. X-ray photoelectron spectroscopy (XPS) analysis was utilised to examine some of the pre-treated rubber particles. The results showed that doubling the net mixing time of all mix constituents together enhanced the Rubcrete slump by an average of 22%, and the compressive strength by up to 8%. Mixing rubber with dry cement before adding to the mix increased the compressive strength by up to 3%. Pre-treatment using water was more effective than other chemicals in enhancing the Rubcrete workability. Regardless of the treatment material type, the longer the time of the treatment, the more cleaning of rubber occurred. Significant Rubcrete flexural strength increase occurred when using 1.5% fibre content of both steel fibre and polypropylene fibre.
Experimental and Numerical Investigation of the Influence of Process Parameters in Incremental Sheet Metal Forming on Residual Stresses
Authors: Maqbool Fawad , Bambach Markus
Published: April 2019

The aim of this study is to analyze the co-relation between the geometrical accuracy of parts formed by single-point incremental forming (SPIF) and the resulting distribution of the residual stresses induced in the material as a function of the different process parameters of the SPIF process. The study was performed for a pyramidal frustum manufactured by varying the process parameters of SPIF, i.e., tool diameter, tool step-down, and wall-angle. The hole-drilling strain gage method was used to determine the residual stresses in the manufactured pyramids. Further, small strips were laser cut from the pyramids, and the curvature of the strips was measured. The curvature of the strips is a result of the intensity and distribution of the residual stresses, which in turn depends on the selected values of the process parameters. A validated numerical model of SPIF was used to determine the residual stresses parallel and perpendicular to the direction of tool motion at the center of a strip cut from the numerical model in clamped, unclamped, and trimmed states. Further, the change in the bending moment of a strip that occurred upon unclamping and trimming was calculated. Experimental and numerical investigations reveal that the most significant parameter in residual stress build-up and the reduction of geometrical accuracy is the wall angle. Upon unclamping, the highest change in the residual stresses and bending moment occurred with the largest tool step-down and tool diameter. Upon trimming, the magnitude of the residual stresses and bending moment changed the most with the largest tool step-down in both directions, whereas the change was highest with the smallest tool diameter in the transverse direction of the tool motion. Furthermore, upon trimming, the geometric deviations were highest with the large wall angles in the transverse direction of the tool motion. Overall, the effect of changing process parameters on the residual stress state and geometrical accuracy was more pronounced in the transverse direction of the tool motion.
X-ray Determination of Compressive Residual Stresses in Spring Steel Generated by High-Speed Water Quenching
Authors: Lozano Diego E. , Totten George E. , Bedolla-Gil Yaneth , Guerrero-Mata Martha , Carpio Marcel , Martinez-Cazares Gabriela M.
Published: April 2019

Automotive components manufacturers use the 5160 steel in leaf and coil springs. The industrial heat treatment process consists in austenitizing followed by the oil quenching and tempering process. Typically, compressive residual stresses are induced by shot peening on the surface of automotive springs to bestow compressive residual stresses that improve the fatigue resistance and increase the service life of the parts after heat treatment. In this work, a high-speed quenching was used to achieve compressive residual stresses on the surface of AISI/SAE 5160 steel samples by producing high thermal gradients and interrupting the cooling in order to generate a case-core microstructure. A special laboratory equipment was designed and built, which uses water as the quenching media in a high-speed water chamber. The severity of the cooling was characterized with embedded thermocouples to obtain the cooling curves at different depths from the surface. Samples were cooled for various times to produce different hardened case depths. The microstructure of specimens was observed with a scanning electron microscope (SEM). X-ray diffraction (XRD) was used to estimate the magnitude of residual stresses on the surface of the specimens. Compressive residual stresses at the surface and sub-surface of about −700 MPa were obtained.
High Optical Response of Niobium-Doped WSe2-Layered Crystals
Authors: Hsu Hung-Pin , Lin Der-Yuh , Jheng Jhin-Jhong , Lin Pin-Cheng , Ko Tsung-Shine
Published: April 2019

The optical properties of WSe2-layered crystals doped with 0.5% niobium (Nb) grown by the chemical vapor transport method were characterized by piezoreflectance (PzR), photoconductivity (PC) spectroscopy, frequency-dependent photocurrent, and time-resolved photoresponse. With the incorporation of 0.5% Nb, the WSe2 crystal showed slight blue shifts in the near band edge excitonic transitions and exhibited strongly enhanced photoresponsivity. Frequency-dependent photocurrent and time-resolved photoresponse were measured to explore the kinetic decay processes of carriers. Our results show the potential application of layered crystals for photodetection devices based on Nb-doped WSe2-layered crystals.
Solvent-Free and Scalable Procedure to Prepare PYR13TFSI/LiTFSI/PVDF–HFP Thermoplastic Electrolytes with Controlled Phase Separation and Enhanced Li Ion Diffusion
Authors: Gregorio Víctor , García Nuria , Tiemblo Pilar
Published: April 2019

Solid electrolytes for Li transport have been prepared by melt-compounding in one single step. Electrolytes are composed of polyvinylidene fluoride–hexafluoropropylene (PVDF–HFP) with PYR13TFSI on its own or with varying concentration of LiTFSI. While the extrusion of PVDF–HFP with PYR13TFSI is possible up to relatively high liquid fractions, the compatibility of PVDF–HFP with LiTFSI/PYR13TFSI solutions is much lower. An organo-modified sepiolite with D-α-tocopherol polyethylene glycol 1000 succinate (TPGS-S) can be used to enhance the compatibility of these blends and allows to prepare homogeneous PYR13TFSI/LiTFSI/PVDF–HFP electrolytes with controlled microphase separations by melt-compounding. The structure and morphology of the electrolytes has been studied by FTIR, differential scanning calorimetry (DSC), SEM, and AFM. Their mechanical properties have been studied by classical strain–stress experiments. Finally, ionic conductivity has been studied in the −50 to 90 °C temperature range and in diffusivity at 25 °C by PFG-NMR. These electrolytes prove to have a microphase-separated morphology and ionic conductivity which depends mainly on their composition, and a mechanical behavior typical of common thermoplastic polymers, which makes them very easy to handle. Then, in this solvent-free and scalable fashion, it is possible to prepare electrolytes like those prepared by solvent casting, but in few minutes instead of several hours or days, without solvent evaporation steps, and with ionic conductivities, which are very similar for the same compositions, above 0.1 mS·cm−1 at 25 °C. In addition, some of the electrolytes have been prepared with high concentration of Li ion, what has allowed the anion exchange Li transport mechanism to contribute significantly to the overall Li diffusivity, making DLi become similar and even clearly greater than DTFSI.
Complex Multi-System Integration Problems Associated with Titanium Metalworking and Manufacture: System of Systems Aproach—Part I
Authors: Stroud Adam , Ertas Atila
Published: April 2019

Titanium has an excellent combination of properties that make it an attractive material for use in aerospace applications. The one area in which titanium is not aligned with customer needs is affordability. Components made from titanium are many times more expensive than those manufactured from other alloys. The supply chain of an extruded product is no exception. A breakthrough in extrusion cost reduction would enable wider adoption of titanium in many structural member applications. In an effort to accomplish any breakthrough in titanium component costs, the entire supply chain for manufacturing should be evaluated simultaneously. Due to the complex interaction of the many facets of the systems in a manufacturing supply chain, it is inferred that the supply chain in its entirety must be the focus of the design activity in order to be successful. Design improvements on a single facet of manufacture may have little to no effect on the manufacture of the component. If the improvement has a detrimental impact on another system in the supply chain, overall performance may be lowered. The use of a system of systems’ (SoS) design approach was used due to its capability to address complex multi-system integration problems associated with titanium metalworking and manufacture.
Sintering of Ti(C,N)-WC/Mo2C-(Ta,Nb)C-Co/Ni Cermets Investigated by CO and N2 Outgassing
Authors: Schwarz Viktoria , Scagnetto Fabio , Lengauer Walter
Published: April 2019

Cermets of the type Ti(C,N)-WC/Mo2C-(Ta,Nb)C-Co/Ni with changing [Mo]/([Mo] + [W]) ratio were subjected to an investigation of outgassing of CO and N2 upon sintering. Quantification of CO and N2 was performed by gas calibration, measurement of masses 12 (12C), 14 (14N) and 28 (28CO and 28N2), as well as C, N, O analysis of the samples before and after sintering. The formation of CO occurs at lower temperatures than that of N2, both gases being completely evolved already at solid-state sintering conditions. If pre-alloyed powders are employed in the starting formulation, the amount of evolved gases is substantially reduced, because part of the formation of mixed hard phases is anticipated. Changing binder composition from Co:Ni = 1:1 to 2:1 and 3:1 does not change the outgassing characteristics, while different batches of nominally the same Ti(C,N) powder can have significant influence. Mass spectrometry is a most valuable in situ tool for getting insight into the metallurgical reactions occurring upon sintering. These reactions result in the typical microstructure and influence the properties of cermets.