bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Disciplines and humanities in Engineering Training in the Context of the FSES 3++
Authors: Vasilyeva V. D.
Published: June 2019

The article discusses the role of social disciplines and humanities in new educational programmes of engineering training, updated in connection with the introduction of HE FSES 3++. The notion of “general cultural competencies” is no longer used in the new educational standards although the “universal competencies” of HE FSES 3++ still correlate with the indicators of general human culture. The article considers the possibilities of the development of universal competencies in approximate basic educational programmes taking the project in the educational direction of 03.09.01 “Computer science and computing” as an example. The importance of social disciplines and humanities to form universal competences is noted. These disciplines provide the continuity of the educational process of the younger generation. The article gives a brief summary of the content of the proposed social disciplines and humanities, describes the conditions for its variation, possible forms of learning activities that ensure the development of universal competencies of future engineers.
Transformation of the System of Training Specialists during the Transition to FSES 3++
Authors: Bakhtizin R. N. , Baulin O. A. , Mazitov R. M. , Shaikhutdinova N. A.
Published: June 2019

Currently, the universities in the Russian Federation are engaged in the updating of the educational programs being implemented, in accordance with the requirements of the Federal State Educational Standard 3 ++. The article provides information on the conceptual changes in the State Educational Standard, Federal State Educational Standard, and Federal State Educational Standard 3 ++ , as well as on the new opportunities universities have in connection with the introduction of the “two plus” generation standard. By an example of the project “NetworkElectronicUniversityof theRepublicofBashkortostan” the article shows the network interaction on issues of the formation of universal competences. New opportunities for universities during the transition to FSES 3 ++ are considered in the context of globalization conditions. The universities are suggested to be considered not so much as a “talent foundry”, but rather as a presence territory development driver, a space for constant positive changes (4P) due to the comprehensive development of scientific, innovative, socio-cultural activities with concurrent integration into the educational environment. The implementation of such a model within the transition to FSES 3 ++ is proposed to be done by individualizing mass education, building flexible educational trajectories that most meet the needs of the parties involved. At the same time, the so-called soft skills should become an indispensable superstructure for the formation of professional competencies, as without them it is extremely difficult to train specialists able to adapt as quickly as possible to changes in the external environment, and, in conditions of uncertainty of occupational functions in the future, they become more important than hard skills.
The Experience of Using «Virtual Petrolab» – Virtual Petrophysical laboratory for Mobile Devices in the Educational Process
Authors: Shelyago E. V. , Shelyago N. D.
Published: June 2019

The paper highlights the experience in the development and implementation of the “Virtual PetroLab” – virtual petrophysical laboratory for mobile devices (smartphones, tablets) in the educational process. The application was created to help the university professors to deliver the course “Oil formation physics”. The program “Virtual PetroLab” simulates functions of various petrophysical equipment in the lab, possesses built-in methodological instructions on performing laboratory works. The mathematical model of the application allows the student to conduct measuring tasks, make, accumulate and correct his own errors. The paper describes the principles of application design and organization of the educational process with its use. Using of mobile devices as a main platform for a virtual laboratory allowed the maximum involvement of the student audience in the educational process, improved the learning quality during workshops, received positive feedback from the students. The conclusions about high efficiency of using the virtual laboratories for mobile devices when teaching technical discipline are drawn.
Regional University: Guidelines for Self-Renewal
Authors: Bazhenova N. G.
Published: June 2019

The article presents the history of formation, current state and prospects of development ofSholom-AleichemPriamurskyStateUniversityas the main guidelines for self-renewal of the regional University. The issues of self-renewal and self-development of the organization are viewed through strategic projects and implementation of a change management model. The development of the territorial entity of theRussian Federationis impossible without the development of an educational cluster on its territory. After 50 years of existence of the Jewish Autonomous Region, it became necessary to develop higher education institutions for training personnel that could meet the internal needs of the socio-economic sphere of the region. The author describes external and internal factors that cause the processes of self-renewal of the education system. New challenges, objective demands of the region should be an integral part of the system of self-development of the regional University. A modern regional University as a self-developing system can and should become not just a “filter” for regional innovations, but also the most important tool for their promotion on the territory. It is able to generate new cohorts of active and qualified specialists, who are integrated into the region, grounded in it and able to create new areas of economic and social activities, new jobs. In this case, it is already a two-way process. Despite its dynamics of development,Sholom-AleichemPrimurskyStateUniversityremains a regional university whose strategic goal is to be an educational, research, innovation and cultural regional centre. It focuses on training highly qualified personnel and consolidating intellectual resources that can improve the quality of life, preserve and develop the culture of the Jewish Autonomous Region andRussiaas a whole in the Far Eastern region.
The System of Environmental Education in the Regional University
Authors: Klinskaya E. O.
Published: June 2019

The solution of environmental problems, both on global and regional level, is possible only when a new type of ecological culture is formed and ecologization of education is provided. The complicated ecological situation in the world and the low level of environmental awareness of the population necessitate constant improvement of environmental education and enlightenment. The article focuses on these problems and describes the system of environmental education created inSholom-AleichemPriamurskyStateUniversity, which is implemented through different types of teachers’ and students’ activities. The University trains bachelors, masters and postgraduates in the field of ecology and environmental management. In-depth study of environmental problems contributes to the organization of research activities of students. The results of students’ and teachers’ scientific research are tested at scientific conferences, environmental forums at different levels. Special importance in the system of environmental education of the University is given to working with applicants. In this regard University is implementing a series of new modern projects. The Department of geography, ecology and environmental law conducts a scientific ecological and geological circle for students of 8-11 grades in Birobidzhan. Teachers of the Department have published teaching aids, textbooks, educational guides to help school teachers of geography, biology, chemistry in greening the natural cycle subjects. The University has established the Center for environmental education providing the development of ecological culture and moral guidelines in environmental sphere. The paper makes special emphasis on the students’ extracurricular activities and environmental protection work.
About Subjectivity of a University Student in Educational Activity
Authors: Fishman B. E.
Published: June 2019

The subjectivity of a university student in educational activities is considered as a significant factor of the compliance between the existing state of the university educational system and the requirements placed on it. The article focuses on the imbalance of information support of educational activities, the lack of personal characteristics of students in this provision. First of all, this refers to the indicators of students’ development processes, their value systems, and the choice of activity strategies. A review of the results of empirical studies that characterize students in the current educational situation is carried out. As part of a study aimed at identifying students’ individual academic strategies, a technique has been proposed to define the value-semantic determination of student activity. This method enables determining the student’s value preferences in the space of possible components of his activity. The student performs pair comparisons of the various components of his activity and in each pair chooses the component that is more important for him. According to the results of comparisons, a hierarchy for each student is determined which reflects his value preferences in the space of possible activity. The analysis of such hierarchies indicates that only 27,6% of students characterize the dominance of the processes of formation of their subjectivity. At the same time, 52,6% of students show incomplete personal subjectivity. And 19,8% of students in their activities are guided by the existing situation and external stimulation. The analysis of the general hierarchy reflecting the value preferences of the considered sample of students in the space of possible activities was performed.
Department of a University and Social Sphere of the Region
Authors: Shapovalova O. E. , Shklyar N. V.
Published: June 2019

One of the main structural units of the University is the Department. Its quality largely determines the image of the institution of higher education, its attractiveness for potential students. Special importance is given to the profiling, graduating Department, organizing research work and practical training of students. In this regard, this article summarizes the five-year experience of one of the departments of the regional University in the aspect of optimization and meeting the social demands to education. The leading method of research is a systematic analysis of the main activities of the Department of correctional pedagogy, psychology and speech therapy, staffed by highly qualified specialists. The article presents the most significant achievements of this Department, which justify its impact on the sphere of educational needs of society. Throughout the considered time period, the Department of correctional pedagogy, psychologists and speech therapy conducted training and retraining of psychological and pedagogical personnel soughed after in the Jewish Autonomous region for the system of special and inclusive education for persons with disabilities. At the same time the Department carried out an effective scientific and practical interaction with the pedagogical community of the region. The materials and results of the presented study were experimentally tested, implemented in the educational process and repeatedly discussed at the meetings of the Department, as well as during scientific seminars and conferences. The gained experience can be useful for managers and scholars of the departments.
University and Professional Society of Social Workers as Subjects of Personnel Training
Authors: Vorotilkina I. M. , Koroleva I. V.
Published: June 2019

In modern society, there is much concern about training highly qualified specialists in the field of social work. Both higher education institutions that provide this training and the professional community are interested in it. The effectiveness of the social institution activity depends on how the personnel is prepared, what competencies and the level of professionalism it possesses. Equal partnership between educational and professional communities will enable university to respond quickly to changes in the economy and the needs of the market, to train unique specialists according to professional standards. The article highlights the cooperation experience of the Department of Service, Advertising and Social Work of Sholom-Aleichem Priamursky State University with the professional community of social workers. The authors present forms and methods of the organization of social partnership as a necessary condition for training future social workers and experts in social work. Different methods of training highly qualified personnel are also shown. The authors have identified the main trajectories of interaction between the University and the professional community of social workers which are determined by the content of educational standards. They include the formation of the educational programme, the involvement of social workers in the educational process, the provision of employment, postgraduate training of personnel. The article pays special attention to the problems of profiling educational programs at universities in small regions. The authors believe that the narrow definition of educational program specialization is connected with the potential lack of demand for personnel while a shortage in specialists is maintained. The authors consider volunteering as an additional resource for the development of professional competencies in the field of social work and a channel for effective interaction between the University and the professional community.
The CDIO ++ Approach to University Faculty Advance Training for Research and Teaching Activities
Authors: Chuchalin A. I.
Published: June 2019

A review of the literature on university faculty advanced training for research and teaching activities is presented. Based on the analysis of the experience of Russian and foreign universities, the principles for developing a modern faculty advanced training system at the university are set out responding to the challenges associated with the ongoing and expected changes in the content and technology of student training, primarily in the field of STEM. It is proposed to use the CDIO ++ approach for advanced training of faculty of various categories (professor, associate professor, assistant) to research and teaching activities in the conditions of division of labor when creating and implementing educational products at various stages of their life cycle. The distribution of academic staff potential is shown and an assessment of the resources of a program for faculty advanced training is given on the basis of the CDIO ++ approach for a hypothetical university with a given structure and established priorities for faculty members of various categories.
Universities and Cities in Provincial Russia
Authors: Zborovsky G. E. , Ambarova P. A.
Published: June 2019

The analysis of higher education (HE) inRussiafocuses on the complicated issues of the relationships between higher education institutions (HEIs) and provincial cities. The authors characterize different typologies of Russian HEIs and cities. It is suggested to distinguish between the HEIs related to the core of HE, semi-periphery, and to the periphery. The situation of peripheral HEIs that are located mainly in provincial cities seems to be the most complicated. Recently, about 300 HEIs and more than 800 branches of universities, a significant part of which belongs to the peripheral group, ceased to exist autonomously. Today the fate of some other provincial HEIs is yet to be defined. Meanwhile, the future of the young people is also tied to the HEIs’s destiny as well as the future of the cities’ population, where they are located. The analysis of the materials based on the authors’ empirical research conducted in the Ural Federal District (UFD) revealed that the elimination of autonomous universities, their transformation into branches and weakening in such a way of the HE in the medium, big and even large cities of the Russian province lead to stagnation and depression of these cities. One of the main factors of this situation is the mass educational migration of young people. The study discusses certain ideas for positive solution of these problems regarding the relationship of provincial Russian universities and cities, which could lead to their preservation and development.
State Examination as a Way to Assess Postgraduate Students’ Teaching Competencies
Authors: Bednyi B. I. , Dyatlova K. D. , Rybakov N. V.
Published: June 2019

The article discusses the system for developing and assessing teaching competencies of PhD program graduates. The experience of Russian universities in conducting the final state examination in postgraduate schools is considered. The authors analyze the options for the distribution of the competencies being assessed between the two parts of the final state certification of postgraduate students: the state examination and the defense of their research report. The system developed and implemented at Lobachevsky University for postgraduate students’ step-by-step training for a teaching career at a higher education institution is discussed in detail, including: 1) theoretical training in the framework of the discipline “Psychology and Pedagogy of Higher Education”, 2) teaching practice, 3) preparation of a study manual based on the results of the postgraduate student’s dissertation research, and its defense at the final state examination. Assessments of the practice-oriented format of the state examination by postgraduate students are presented.
Market Mechanisms as a Social Deadlock for Russian Education
Authors: Osipov A. M.
Published: June 2019

InRussia, the preference of the educational policy for market paths has been being formed for nearly thirty years. The mechanisms, consequences and prospects of so called marketization have not been yet studied. The article considers the marketization of education, including higher education, as a scientific and social problem. Basing on foreign and domestic sources, the author proves that the marketization of education is generated by neo-liberal attitude of the financial and economic elites seeking to reduce state budget expenditures in the social sphere and keep up the disintegration of society and to secure their future domination. The state, the bureaucratic apparatus of the education system, educators’ and researchers’ communities do not take up the problem of education marketization and its consequences. The marketization strategy along with its derivatives is taken in society as an axiom, without special studies and research. Due to this education is being dysfunctional, it experiences a protracted institutional crisis, social tensions and losses, whilst the search of ways out of the neoliberal deadlock is postponed up to uncertain future.
Why Pedagogy Needs Clarity in Definition of the Concept of Profession
Authors: Balakireva E. V. , Robotova A. S.
Published: June 2019

The article discusses the pedagogical understanding of the concept of profession as extremely important for the pedagogical community in the conditions of the modern state of education. The authors believe that the current situation in pedagogy is characterized by the confusion of the concepts profession, specialty, qualification, position, imprecise identification of subjects of education (teacher, educator, tutor, pedagogical worker, etc.), which makes it difficult to develop professional and educational standards, ensure their continuity, define labor actions and competencies clearly. For this reason, it would seem, a private matter acquires social, theoretical and practical significance. The logic and content of the article determine the authors’ position in the consideration of the stated topic – they believe that analyzing the specifics of the teaching profession and related concepts requires taking into account the achievements and recommendations of sociology and psychology of professions, studying the possibilities of the pedagogical professiology. Consideration of the problem only from within the pedagogy itself limits the possibilities of disciplinary analysis, the activity of scientific reflection, the creation of holistic ideas on the teaching profession as a significant humanitarian activity in society, which initially carries humanitarianism as a leading quality. The authors critically consider the Professional standard of a teacher, in which they find contradictory positions, and come to a conclusion about the need for the clear scientific and pedagogical understanding of the concepts of profession, professionalism, professional, specialty, qualification, activity, labor functions, competencies.
7 Years later: Some Thoughts on the Developing of Qualification Framework
Authors: Budzinskaya O. V. , Sheinbaum V. S.
Published: June 2019

The article addresses the problem of combining the emerging country’s new regulatory framework in the field of qualifications, based on professional standards, with the international standards of the Association “WorldSkills International” and corporate standards used in the development and evaluation of personnel, based on the competence approach. The authors focus on the proposals to overcome the differences in the conceptual apparatus relating to a term “qualification”, which is interpreted differently in academic and business communities. The article discusses the possibilities of fixing the qualifications of employees directly in the professional standards that determine the requirements for them. Today there are three approaches that are applied to unite and standardize qualification requirements. The issue is to harmonize them in order to create the national qualification system where the key terms – “expertise”, “competency” and “qualification” are properly aligned.
Training of Competitive Graduates Based on the Educational Standard of the ITMO University
Authors: Shekhonin A. A. , Voznesenskaya A. O. , Bakholdin A. V. , Gavrilina O. A.
Published: June 2019

The paper presents the concept, structure and features ofITMOUniversity’s independently established educational standard of a new generation. The standard has been developed on the basis of Federal State Educational Standard of Higher Education 3++, professional and international standards of engineering education, foresight forecasts of world scientific and technological development. The harmonious intellectual, cultural and moral development, as well as the formation of a professionally competitive personality is ensured by the implementation in the educational programs of the ITMO Code. TheITMOUniversityhas created mechanisms for the formation of actual requirements for the preparation of competitive professionals demanded at an international level. The authors propose the design and implementation system of the educational programs based on integration of the fundamental classical technical education, enhanced development of the universal, common and professional competencies, and extended implementation of the modern theoretical and applied practice-oriented researches, which are supported an active participation of industrial companies and research organizations in educational activities. An interdisciplinary content of educational programs together with orientation to individualization of education and introduction of advanced educational technologies including design, digital, network etc. provides a stable technology platform to achieve the standard requirements for learning outcomes.
Flipped Classroom for Doctoral Students: Evaluating the Effectivness
Authors: Volchenkova K. N.
Published: June 2019

The demand of Industry 4.0 for creative researchers able to adopt to the changing world and think out of the box puts forward the question of education technologies used to prepare such specialists. Though many new education technologies have appeared recently their effectiveness has not yet been proved to be introduced into tertiary education in a large scale. The author presents the evidence for the flipped classroom technology effectiveness. The paper describes the rationale and content of the doctoral program course “English for Research Purposes” delivered using flipped classroom approach. The course was piloted in September-May, 2017/2018 academic year with 197 doctoral students participating. Both quantitative and qualitative evaluation of the flipped classroom was made. Direct education outcomes (students’ scores at the end of the course and attendance rates) and indirect education outcomes (students’ attitudes, perceptions, and feelings towards the course; students’ empowerment and development in the course) were measured using analysis of variance with repeated measures and Likert Scale surveys. The results showed that a general increase in students’ ratings of the effectiveness of the flipped classroom elements was observed during the course, the students’ scores increased 11,3% in comparison with the results of the 2016/2017 academic year where a traditional approach was used. The results of the research can be used to modernize the education process of doctoral students’ training based on flipped classroom technology both at the universities ofRussian Federationand at foreign universities.
BIMBINGAN BELAJAR BAHASA INGGRIS BAGI SEKOLAH DASAR DI DESA BAHARI KECAMATAN TOJO KABUPATEN TOJO UNA UNA
Authors: Putra B Retno Adhy , Rafii Muh.
Published: June 2019

Kegiatan pengabdian masyarakat yang dilakukan ini adalah pengajaran Bahasa Inggris untuk pembelajar usia muda, yaitu pengajaran Bahasa Inggris untuk anak-anak (English for Children) dalam bentuk bimbingan belajar bahasa Inggris yang diperuntukkan bagi Sekolah Dasar (SD). Tujuan pengajaran bahasa yang dilaksanakan ini adalah untuk mengetahui cara yang tepat dalam menyediakan bimbingan belajar Bahasa Inggris untuk anak-anak usia sekolah dasar khususnya di Desa Bahari, serta untuk mengetahui bahwa les atau bimbingan belajar bahasa Inggris efektif untuk anak-anak usia Sekolah Dasar. Kegiatan bimbingan belajar Bahasa Inggris ini dilaksanakan di Sekolah Dasar Desa Bahari, Kecamatan Tojo Kabupaten Tojo Una Una. Bimbingan belajar cukup efektif membantu anak usia Sekolah Dasar Desa Bahari untuk meningkatkan pengetahuan seperti Alpabet dalam menggunakan Bahasa Inggris. Sisamping itu juga, Sekolah Dasar Desa Bahari tidak memiliki tenaga pendidik Bahasa Inggris dikarenakan kurangnya tenaga pendidik di Kecamatan Tojo khususnya di Desa Bahari. Metode pengajaran memperkenalkan dasar-dasar Bahasa Inggris seperti Alphabet, percakapan dan tebak kata dan bermain (game). Hasilnya, siswa-siswa SD Desa Bahasari mampu mengikuti dan memahami materi yang diajarkan dalam bimbingan belajar. Kata Kunci : bimbingan belajar, bahasa Inggris, pengajaran
Karakteristik Histopatologi Melanoma Maligna di Bagian Patologi Anatomi RSUP Dr. Moh. Hoesin Palembang Tahun 2009-2013
Authors: Ariesta Nisrina , Musa Zulkarnain , Septadina Indri Seta
Published: June 2019

Melanoma maligna merupakan tumor ganas yang berasal dari melanosit dengan gambaran berupa lesi kehitam-hitaman pada kulit. Melanoma maligna merupakan satu dari tiga jenis kanker kulit yang mempunyai insiden terendah namun angka kematian yang disebabkannya cenderung lebih besar yaitu 75% akibat kanker kulit. Penelitian ini bertujuan untuk mengetahui karakteristik histopatologi melanoma maligna pada sediaan di Bagian Patologi Anatomi RSUP Dr. Mohammad Hoesin Palembang pada tahun 2009-2013. Jenis penelitian yang digunakan adalah metode deskriptif observasional dengan pendekatan cross sectional. Dari 29.175 rekam medik pasien di Bagian Patologi Anatomi RSMH selama 2009-2013, diperoleh 30 kasus melanoma maligna yang memenuhi kriteria inklusi. Angka kejadian melanoma maligna di Bagian Patologi Anatomi RSUP Dr. Mohammad Hoesin Palembang tahun 2009-2013 adalah 0.103%. Melanoma maligna lebih banyak ditemukan pada perempuan (70%) daripada laki-laki (30%), dan paling sering terjadi pada kelompok usia  45-53 tahun dengan persentase 30%. Karakteristik histopatologi yang paling banyak ditemukan dalam penelitian ini adalah subtipe nodular melanoma (100%). Angka kejadian melanoma maligna di Bagian Patologi Anatomi RSMH tahun 2009-2013 adalah 0,103%, dengan angka kejadian tertinggi pada tahun 2012 yaitu 0.28%. Nodular melanoma merupakan subtipe yang paling banyak ditemukan.
Pengaruh Paparan Gas Amonia Terhadap Perubahan Kadar Serum SGOT dan SGPT pada Kelompok Berisiko
Authors: Saputra Andi , Irfannuddin Irfannuddin , Swanny Swanny
Published: June 2019

Amonia merupakan zat yang beracun dan memiliki bau yang khas (menyengat) yang menimbulkan keresahan dan resistensi dari masyarakat sekitarnya. Jika terpapar amonia akan menimbulkan dampak kesehatan salah satunya berupa kerusakan sel hepar yang dapat diketahui dengan mengukur jumlah enzim transminase yaitu Serum Glutamic Oxaloacetic Transaminase (SGOT) dan Serum Glutamic Pyruvic Transaminase (SGPT). Tujuan penelitian ini adalah untuk mengetahui pengaruh gas amonia terhadap perubahan kadar serum SGOT dan SGPT pada kelompok berisiko di Kota Palembang. Penelitian ini Design cross sectional dengan quota sampling. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 22 orang di Kelurahan Karang Anyar Palembng dan 22 di Desa Pajar Bulan Ogan Ilir. Pengukuran kadar udara ambient oleh Petugas BTKL Palembang dan untuk pemeriksaan kadar serum SGOT dan SGPT diperiksa di Laboratorium BBLK Palembang. Hasil : Kadar udara ambient amonia di Kelurahan Karang Anyar sebesar 2,18 ppm lebih tinggi di bandingkan di Desa Pajar Bulan sebesar 0,0020 ppm. Rerata  kadar serum SGOT pada kelompok berisiko (19,42±3,06) lebih tinggi dibandingkan kelompok tidak berisiko (19,40±4,18) dengan p value =0,984 dan Rerata  kadar serum SGPT pada kelompok berisiko (15,74±4,57) lebih tinggi dibandingkan kelompok tidak berisiko (15,68±4,49) dengan p value =0,971. Tidak Terdapat Perbedaan Rerata Kadar Serum SGOT dan SGPT pada kelompok berisko dan kelompok tidak berisiko
Hubungan Karakteristik, Hiperglikemi, dan Kerusakan Saraf Pasien Neuropati Diabetik di RSMH Palembang
Authors: Suri Muthiah Hasnah , Haddani Hasnawi , Sinulingga Sadakata
Published: June 2019

Neuropati diabetik merupakan komplikasi tersering dari penyakit diabetik. Faktor risiko yang mempengaruhi timbulnya neuropati diabetik adalah lamanya menderita DM, pertambahan usia, jenis kelamin, dan hiperglikemi. Kerusakan saraf pada neuropati diabetik dapat diketahui dengan pemeriksaan ENMG. Tujuan penelitian ini untuk menganalisis hubungan karakteristik, hiperglikemi, dan kerusakan saraf pada pasien neuropati diabetik berdasarkan pemeriksaan ENMG. Metode penelitian adalah analitik observasional dengan desain cross sectional. Sebanyak 63 sampel diambil dari rekam medis dan hasil pemeriksaan ENMG pasien neuropati diabetik di RSMH Palembang periode tahun 2013-2014. Hasil didapatkan penderita neuropati diabetik perempuan 32 orang (50,8%), laki-laki 31 orang (49,2%), usia <55 tahun 25 orang (39,7%), usia >55 tahun 38 orang (60,3%), lama menderita DM <5 tahun 13 orang (20,63%), lama menderita DM >5 tahun 50 orang (79,37%), kadar HbA1C <8 31 orang (49,21), dan kadar HbA1C >8 32 orang (50,79%). Kerusakan saraf tipe axonal-demyelinating 44 orang (69,8%) dan tipe demyelinating 19 orang (30,2%). Tidak ada hubungan antara usia dan kerusakan saraf (p=0,796). Tidak ada hubungan antara jenis kelamin dan kerusakan saraf (p=0,066). Tidak ada hubungan antara lama menderita DM dan kerusakan saraf (p=0,169). Ada hubungan antara kadar HbA1C dan kerusakan saraf (p=0,045; OR 3,13; CI95% 1,002-9,774). Kesimpulan didapatkan tidak ada hubungan antara usia, jenis kelamin, lamanya menderita DM dan kerusakan saraf. Ada hubungan hiperglikemi dan kerusakan saraf.
Hubungan Polimorfisme Gen XRCC1 Arg399Gln Terhadap Kejadian Kanker Serviks Pada Wanita Ras Melayu
Authors: Sary Mega , Legiran Legiran , Saleh Irsan
Published: June 2019

Kanker serviks merupakan kanker yang terjadi pada serviks atau leher rahim, suatu daerah yang terletak pada organ reproduksi wanita yang merupakan pintu masuk ke arah rahim, letaknya antara rahim (uterus) dan liang senggama atau vagina. Insiden terjadinya kanker serviks dipengaruhi oleh Human Papiloma Virus (HPV), usia, usia terlalu muda berhubungan seksual, paritas, riwayat keluarga dan RAS. Gen XRCC1 sebagai perancah dalam BER yang terlibat dalam membantu memperbaiki kesalahan-kesalahan selama replikasi DNA serta  menjaga integritas genom. Single Nukleotida Polymorphism (SNP) di XRCC1 telah dikaitkan dengan pengembangan yang terjadi pada kanker serviks yang dapat mengurangi aktivitas perbaikan DNA, meningkatkan terjadinya mutasi sehingga kerentanan terhadap kanker. Penelitian ini bertujuan untuk melihat adakah hubungan polimorfisme gen XRCC1 Arg399Gln dengan kejadian kanker serviks. Penelitian ini merupakan penelitian observasional analitik dengan desain case-control dengan jumlah sampel sebanyak 35 orang wanita kanker serviks dan 35 orang wanita normal yang setiap sampel memiliki RAS melayu Jambi. Identifikasi polimorfisme gen XRCC1 Arg399Gln dilakukan dengan teknik PCR-RLFP amplifikasi dengan primer spesifik yang digunakan untuk melihat mutagenesis. Hasil analisis dengan uji Chi-Square genotipe G/G (Wild Type), G/A (Mutant Heterozigot) dan G/A (Mutant Heterozigot) terhadap kanker serviks nilai ? = 0,032 (OR : 10.074 ; CI : 1,186 -85,570). Kesimpulan ada hubungan polimorfisme genotip gen XRCC1 Arg399Gln terhadap kejadian kanker serviks pada wanita RAS Melayu Jambi.
Pengaruh Ekstrak Bunga Kembang Sepatu (Hibiscus Rosa-Sinensis Linn.) terhadap Epididimis, Prostat dan Vesikula Seminalis
Authors: Carolin Bunga Tiara , Salni Salni , Nita Sri
Published: June 2019

Hibiscus rosa-sinensis Linn. merupakan salah satu tanaman obat  di Indonesia yang digunakan sebagai kontrasepsi pria. Bunga kembang sepatu mengandung flavonoid yang dapat menurunkan testosteron. Tujuan penelitian ini untuk mengetahui pengaruh ekstrak bunga kembang sepatu terhadap berat epididimis, tebal epitel epididimis cauda, berat prostat dan vesikula seminalis tikus jantan. Penelitian ini merupakan penelitian eksperimental dengan menggunakan Rancangan Acak Lengkap (RAL). Sampel dalam penelitian ini menggunakan 25 tikus jantan strain Sprague Dawley® usia 60-70 hari dengan berat badan 200-210 gram. Dosis perlakuan 200 mg/kgBB, 300 mg/kgBB, 400 mg/kgBB, 500 mg/kgBB selama 30 hari. Data disajikan dalam bentuk tabel serta narasi untuk menginterpretasikan data tersebut.Hasil penelitian menunjukan adanya penurunan berat epididimis pada kelompok perlakuan dibanding kelompok kontrol (p=0,000), terjadi juga penyusutan tebal epitel epididimis cauda (p=0,021), penurunan berat prostat dan vesikula seminalis antara kelompok perlakuan dibanding kelompok kontrol (p=0,001). Dapat disimpulkan bahwa ada pengaruh ekstrak bunga kembang sepatu tehadap epididimis, prostat dan vesikula seminalis. Pengaruh tersebut kemungkinan disebabkan kandungan bahan kimia yang ada di dalam bunga kembang sepatu yang bersifat antifertilitas.
Perbandingan antara Pemberian Fraksi Daun Beluntas (Pluchea Indica Lees) dan Ketokonazol Secara Invitro Terhadap Candida Albicans
Authors: Marsasi Bina , Yuwono Yuwono , Salni Salni
Published: June 2019

Daun beluntas bermanfaat sebagai pengobatan flour albus dan discharge yang disebabkan oleh jamur. Penelitian ini bertujuan untuk menemukan aktivitas anti-jamur fraksi pada ekstrak daun beluntas (Pluchea indica Lees) terhadap Candida albicans. Penelitian ini adalah penelitian eksperimental in vitro menggunakan desain studi Posttest-only Control Group Design. Ekstrak metanol diperoleh melalui proses maserasi sedangkan fraksinya melalui fraksinasi cair-cair. Fraksi paling aktif ditentukan oleh uji aktivitas anti jamur. Fraksi paling aktif dengan konsentrasi 10%, 5%, 2,5%, 1,25%, 0,625% dan diameter zona hambat 0,3125% diukur dengan metode pengenceran cairan padat. Kesetaraan dengan obat dinilai melalui analisis regresi, kemudian golongan senyawa aktif ditentukan melalui uji bioautografi menggunakan kromatografi lapis tipis. Hasil penelitian diperoleh metanol-fraksi-air dapat menghambat pertumbuhan Candida albicans sedangkan ekstrak metanol, n-heksana dan etil asetat tidak menghambat. Fraksi metanol air yang memiliki diameter zona hambat mulai pada konsentrasi 0,3125% dengan diameter rata-rata 7,34 mm dan pada konsentrasi 10% diperoleh diameter terbesar sebesar 17,10 mm. Melalui cairan pengencer dan fraksi padat KHM dari fraksi metanol-air dihambat pada konsentrasi 0,3125%. Uji kesetaraan menunjukkan bahwa 1 mg / ml ketokonazol setara dengan 39.561 mg / ml fraksi metanol-air daun beluntas. Senyawa yang menghambat jamur diduga adalah golongan aktif senyawa flavonoid dan alkaloid. Fraksi metanol-air daun beluntas (Pluchea indica Lees) memiliki aktivitas antijamur terhadap Candida albicans secara in vitro.
Uji Efek Antibakteri Propolis Terhadap Escherichia Coli Dan Shigella Dysenteriae Secara In Vitro
Authors: Ferdi Roni , Saleh Irsan , Theodorus Theodorus , Salni Salni
Published: June 2019

Bakteri yang sering menjadi penyebab diare infeksi adalah Escherichia coli dan Shigella dysenteriae. Penggunaan antibiotik yang berlebihan dan kurang rasional pada kasus diare mendorong terjadinya perkembangan resistensi patogen multi obat. Propolis merupakan salah satu solusi untuk mengatasi infeksi diare. Tujuan penelitian ini untuk mengetahui kemampuan efek antibakteri ekstrak propolis terhadap bakteri Escherichia coli dan Shigella dysenteriae dalam pengujian secara in vitro dengan berbagai konsentrasi. Penelitian eksperimen laboratorium secara in vitro. Sampel dalam penelitian ini adalah bakteri Escherichia coli dan Shigella dysenteriae dengan tahapan penelitian dimulai dari proses ekstraksi dilakukan dengan menggunakan  metode ekstraksi bertingkat. Hasil penelitian menunjukkan konsentrasi fraksi n-heksan terkecil yang masih menghambat pertumbuhan bakteri Escherichia coli dan Shigella dysenteriae adalah 250 µg/ml dan konsentrasi ini dinyatakan sebagai nilai KHM. Uji kesetaraan konsentrasi 250 µg/ml fraksi n-heksan propolis setara dengan 4,0 µg/ml ciprofloxacin terhadap Escherichia coli dan setara dengan 4,6 µg/ml ciprofloxacin terhadap Shigella dysenteriae, sedangkan uji kesetaraan konsentrasi 250 µg/ml  fraksi etil asetat propolis setara dengan 5,2 µg/ml ciprofloxacin terhadap Escherichia coli dan setara dengan 4,5 µg/ml ciprofloxacin terhadap Shigella dysenteriae. Kesimpulan penelitian ini adalah Ekstrak n-heksan dan etil asetat propolis memiliki efektifitas antibakteri terhadap Escherichia coli dan Shigella dysenteriae. Fraksi n-heksan dan etil asetat propolis memiliki aktivitas antibakteri yang lebih rendah jika dibandingkan dengan ciprofloxacin dalam menghambat pertumbuhan bakteri Escherichia coli dan Shigella dysenteriae. Senyawa antibakteri yang terdapat dalam fraksi n-heksan dan etil asetat propolis adalah flavonoid dan fenol.
Rasionalitas Penggunaan Antagonis Kalsium Pada Wanita Hamil
Authors: Novianty Novianty , Tanzil Sutomo , Theodorus Theodorus
Published: June 2019

Preeklampsia adalah suatu keadaan hipertensi yang timbul setelah 20 minggu kehamilan disertai dengan proteinuria. Eklampsia adalah preeklampsia yang disertai dengan kejang dan atau koma. Di Indonesia preeklampsia dan eklampsia masih merupakan salah satu penyebab utama kematian ibu dan perinatal. Penelitian ini bertujuan untuk mengetahui pola pemberian antagonis kalsium pada wanita hamil di Rumah Sakit Mohammad Hoesin Palembang. Survei penggunaan obat dilakukan di Ruang Rekam Medis pada November sampai Desember 2013. Populasi penelitian adalah semua pasien hipertensi pada wanita hamil di Instalasi Rawat Inap Departemen Obstetri dan Ginekologi Rumah Sakit Mohammad Hoesin. Sampel berjumlah 63 penderita yang memenuhi kriteria inkulsi. Hasil penelitian bentuk deskriptif dan dalam tabel persentase. Didapatkan 63 wanita hamil yang hipertensi. Hipertensi pada wanita hamil ditemukan pada usia 33-37 tahun (40%). Hipertensi ditemukan pada kehamilan pertama (11.3%). Jenis hipertensi terbanyak adalah derajat dua (68.2%). Antagonis kalsium yang digunakan adalah nifedipin dan amlodipin. Nifedipin diberikan peroral dengan dosis 10 mg satu kali makan dengan frekuensi tiga kali dalam satu hari (100%). Amlodipin diberikan peroral dengan dosis 10 mg satu kali makan dengan frekuensi satu kali dalam satu hari (100%). Magnesium sulfat sering digunakan bersamaan dengan antagonis kalsium (89%). Penggunaan antagonis kalsium pada wanita hamil di Departemen Obstetri dan Ginekologi Rumah Sakit Mohammad Hoesin sudah rasional.
Hubungan Siklus Bioritme dengan Nilai Computer Based Test (Cbt) pada Mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya
Authors: Dita Nurul Salmah Alia , Bahar Erial , Roflin Eddy
Published: June 2019

Tubuh manusia memiliki banyak irama, salah satunya bioritme. Bioritme terdiri dari tiga siklus yaitu, siklus fisik, emosi dan intelektual. Masing-masing siklus memiliki fase positif, negatif dan kritis. Saat mengikuti ujian seseorang memerlukan keadaan fisik, mental, dan intelektual yang baik. Dengan menggunakan siklus bioritme, seseorang dapat melihat keadaan-keadaan tersebut agar dapat mempersiapkan diri ketika ujian. Penelitian ini adalah penelitian analitik observasional dengan desain cross sectional. Sampel terdiri dari 386 mahasiswa Program Studi Pendidikan Dokter Universitas Sriwijaya angkatan 2014 dan 2015 secara total sampling yang memenuhi kriteria inklusi. Data yang diambil berupa data sekunder yang terdiri dari nilai CBT, tanggal ujian, dan jalur masuk yang diperoleh dari bagian akademik Fakultas Kedokteran Universitas Sriwijaya, sedangkan data tanggal lahir, IMT dan nilai IQ diambil dari kuesioner. Data siklus bioritme diambil menggunakan biorhythm software. Pengolahan data dilakukan dengan menggunakan analisis uji Kruskal Wallis dan Regresi Linier. Dari hasil analisis bivariat dengan uji Kruskall Wallis didapatkan nilai IQ memiliki hubungan dengan nilai CBT (p=0,010), jalur masuk universitas memiliki hubungan dengan nilai CBT (p=0,000), dan siklus fisik bioritme berhungan dengan nilai CBT (p=0,011), Namun, pada analisis multivariat (Regresi Linier) siklus fisik bioritme tidak memiliki hubungan dengan nilai CBT. Tidak terdapat hubungan siklus bioritme dengan nilai CBT pada mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Sriwijaya.
Korelasi Antara Kadar Feritin Serum dan Status Gizi Pasien Talasemia-? Mayor
Authors: Rafika Rafika , Marwoto Djoko , Hayati Lusia
Published: June 2019

Talasemia adalah penyakit kronik yang membutuhkan transfusi darah berulang, karena adanya gangguan sintesis hemoglobin akibat mutasi dari satu atau lebih gen globin. Transfusi secara terus menerus dapat menyebabkan terjadinya penimbunan besi dalam tubuh khususnya jantung, hati, dan organ endokrin, serta dapat menyebabkan pertumbuhan yang terhambat dan gizi kurang atau gizi buruk. Penelitian ini bertujuan untuk mengetahui korelasi antara kadar feritin serum dan status gizi pasien talasemia-? mayor di RSUP Dr. Moh. Hoesin Palembang. Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional. Sampel penelitian ini adalah pasien talasemia-? mayor yang menjalani rawat inap di Departemen Ilmu Kesehatan Anak RSUP Dr. Mohammad Hoesin pada bulan Oktober hingga November 2016 yang memenuhi kriteria keikutsertaan. Dari 43 pasien, sebagian besar (60.5%) pasien memiliki  badan kurus sesuai dengan indeks berat badan menurut usia (BB/U) dan berperawakan pendek sesuai indeks tinggi badan menurut usia (TB/U), namun hanya 14.0% pasien memiliki gizi kurang menurut indeks BB/TB.  Didapatkan nilai rata-rata kadar feritin serum 2837.69 ?g/L, dengan rentang 278.7-13867 ?g/L. Hasil uji korelasi antara kadar feritin serum dan status gizi menunjukkan nilai p=0.326 dan nilai r=0.153. Terdapat korelasi yang tidak bermakna antara kadar feritin serum dan status gizi pasien talasemia-? mayor.
Profil Hormon Penderita Disorder of Sex Development (DSD) di RSUP. Dr. Mohammad Hoesin Palembang
Authors: Maritska Ziske , Prananjaya Bintang Arroyantri , Parisa Nita , Quardetta Rovania Yantinez
Published: June 2019

Selain berdasarkan temuan klinis, penentuan diagnosis Disorders of sex development (DSD) juga didukung oleh ragam pemeriksaan penunjang seperti analisis kromosom, radiologi, dan pemeriksaan laboratorium yang salah satunya berupa pemeriksaan kadar hormon. Pemeriksaan kadar hormon dapat memberikan gambaran fungsi gonadal dan adrenal, yang bermanfaat baik untuk penapisan dan juga penentuan diagnosis DSD. Studi yang bertujuan untuk mengidentifikasi profil hormon pasien DSD di Indonesia masih sangat minim, dan studi ini merupakan studi pertama yang meninjau profil hormon DSD di RSUP Dr. Mohammad Hoesin Palembang. Studi ini merupakan studi deskriptif menggunakan data sekunder dari rekam medik pasien DSD yang menjalani pemeriksaan hormon selama periode 2013-2017.  Dari total 173 pasien DSD yang datang berobat ke RSUP Dr. Mohammad Hoesin Palembang selama lima tahun terakhir, hanya 22 (12.72%) pasien yang menjalani pemeriksaan hormon. Ada 13 profil hormon yang diperiksa pada pasien DSD di RSUP Dr. Mohammad Hoesin Palembang dengan hormon testosteron (54.54%) sebagai hormon yang paling sering diperiksa. Pemeriksaan profil hormon sebagai salah satu alat bantu penapisan dan penegakkan diagnosa DSD belum menjadi salah satu pemeriksaan penunjang yang umum dilakukan di RSUP Dr. Mohammad Hoesin Palembang.
The Efficacy of Sauropus androgynus Leaves Extract To Improve Cognitive Function in Wistar Rats Induced Alzheimerâ€™s
Authors: Hidayat Rachmat , Adelia Safitri Raden Ayu , Umar Tungki Pratama , Maretzka Arindi
Published: June 2019

Background

Sauropus androgynus leaves is the substance which has the potency to prevent degenerative processes. Sauropus androgynus leaves has flavonoid as the main component. Flavonoid has antioxidant and anti neuro-inflammation that can be used to prevent Alzheimer dementia. Research purpose is knowing the effect of Sauropus androgynus leaves for the cognitive function and Î²-amyloid expression in the hippocampus of wistar rats.

Methods

Reseacrh was done by in vivo method, where male wistar rats (n=24) were distributed to six groups which consisting of four rats. Group 1: Normal control, group 2: positive control, group 3: standard treatment (B12 vitamin), group 4, 5 and 6 were give Sauropus androgynus leaves extract with the dose of 75 mg/kgBB, 150 mg/kgBB and 300 mg/kgBB, respectively for 28 days. Cognitive function was evaluated by t-maze test, where hippocampal Î²-amyloid expression was tested by immunohistochemistry.

Results

Time differences (day 0-28), alternation ratio distinction (day 0-28) and Î²-amiloid expression were: group 1 (1,84 second; 0,23 unit; 0,518%), group 2 (56,78 second; -0,42 unit; 40,036%), group 3 (34,46 second; -0,25 unit; 33,08%), group 4 (32,83  second; -0,09 unit; 28,88%), group 5 (-3,91 second; 0,42 unit; 14,728%), group 6 (24,25 second; 0,42 unit; 9,4%).

Conclusion

Sauropus androgynus leaves extract at the dose of 150 mg/kgBB and 300 mg/kgBB can maintain cognitive function by decreasing hippocampal Î²-amyloid formation.