bluuebunny/crossref_metadata_2025 huggingface dataset:
Feeling of loneliness and its correlation to self-esteem in children with Asperger’s disorder in Riyadh, Saudi Arabia
Authors:   Psychology Department, College of Education, King Saud University, Riyadh, Saudi Arabia, Al-Owidha Sultan Mousa , Zahran Nevien Mohammed ,   Prince Naif Arab University for Security Sciences, Riyadh, Saudi Arabia
Published: October 2021

Asperger's Disorder (AS) and feeling of loneliness (FOL) are related to low self-esteem (SE) in children as many autistic children do not participate in society. However, there was a need to further explore the correlation between the feeling of loneliness (FOL) and self-esteem in children with AS in the Saudi context. This study aimed at investigating the type of correlation between FOL and SE in the sample of children with AS and typically developing children from primary school pupils in Riyadh. It drew a comparison between the study sample individuals regarding psychological loneliness as well as SE according to the sex variable (male/female) and developmental disorder variable (children with AS and typically developing children). It further discussed the prevalence of psychological loneliness, low self-esteem, and negative social perception in individuals with an autism spectrum disorder. It adopted the descriptive approach (correlative/comparative). The data were statistically analyzed using Pearson's correlation coefficient, two-direction variance analysis (2x2), and T-Test. This is a pioneering study in terms of emphasizing the importance of early detection and intervention to identify children with AS and taking precautionary measures and treatment in the Saudi context. The findings indicated that FOL is negatively correlated to SE in children with AS and typically developing children of both sexes. This result is consistent with the findings of the previous studies. It was also found that male children with AS demonstrated more FOL and less SE than female children with AS. The study also provided some educational recommendations and proposed further research in this area. It also recommended developing training programs and courses for parents to optimally deal with the mentally retarded child.
Factors Associated With Willingness to Share Health Information: Rapid Review
Authors: Naeem Iffat , Quan Hude , Singh Shaminder , Chowdhury Nashit , Chowdhury Mohammad , Saini Vineet , TC Turin
Published: October 2021

Background

To expand research and strategies to prevent disease, comprehensive and real-time data are essential. Health data are increasingly available from platforms such as pharmaceuticals, genomics, health care imaging, medical procedures, wearable devices, and internet activity. Further, health data are integrated with an individual’s sociodemographic information, medical conditions, genetics, treatments, and health care. Ultimately, health information generation and flow are controlled by the patient or participant; however, there is a lack of understanding about the factors that influence willingness to share health information. A synthesis of the current literature on the multifactorial nature of health information sharing preferences is required to understand health information exchange.

Objective

The objectives of this review are to identify peer-reviewed literature that reported factors associated with health information sharing and to organize factors into cohesive themes and present a narrative synthesis of factors related to willingness to share health information.

Methods

This review uses a rapid review methodology to gather literature regarding willingness to share health information within the context of eHealth, which includes electronic health records, personal health records, mobile health information, general health information, or information on social determinants of health. MEDLINE and Google Scholar were searched using keywords such as electronic health records AND data sharing OR sharing preference OR willingness to share. The search was limited to any population that excluded health care workers or practitioners, and the participants aged ≥18 years within the US or Canadian context. The data abstraction process using thematic analysis where any factors associated with sharing health information were highlighted and coded inductively within each article. On the basis of shared meaning, the coded factors were collated into major themes.

Results

A total of 26 research articles met our inclusion criteria and were included in the qualitative analysis. The inductive thematic coding process revealed multiple major themes related to sharing health information.

Conclusions

This review emphasized the importance of data generators’ viewpoints and the complex systems of factors that shape their decision to share health information. The themes explored in this study emphasize the importance of trust at multiple levels to develop effective information exchange partnerships. In the case of improving precision health care, addressing the factors presented here that influence willingness to share information can improve sharing capacity for individuals and allow researchers to reorient their methods to address hesitation in sharing health information.
A Serious Game (Immunitates) About Immunization: Development and Validation Study
Authors: Lima Isabela Dantas de Araujo , Ponce de Leon Casandra Genoveva Rosales Martins , Ribeiro Laiane Medeiros , Silva Izabel Cristina Rodrigues da , Vilela Danielle Monteiro , Fonseca Luciana Mara Monti , Góes Fernanda dos Santos Nogueira de , Funghetto Silvana Schwerz
Published: October 2021

Background

Vaccination is a fundamental part of all levels—local to worldwide—of public health, and it can be considered one of humanity's greatest achievements in the control and elimination of infectious diseases. Teaching immunization and vaccination can be monotonous and tiring. It is necessary to develop new approaches for teaching these themes in nursing school.

Objective

We aimed to develop and validate a serious game about immunization and vaccination for Brazilian nursing students.

Methods

We developed a quiz-type game, Immunitates, using design and educational theoretical models and Brazilian National Health Guidelines. The game’s heuristics and content were evaluated with 2 different instruments by a team of experts. A sample of nursing students evaluated the validity of the game’s heuristics only. We calculated the content validity index (CVI) for each evaluation.

Results

The study included 49 experts and 15 nursing students. All evaluations demonstrated high internal consistency (Cronbach α≥.86). The game’s heuristics (experts: CVI 0.75-1.0; students: CVI 0.67-1.0) and the game’s contents demonstrated validity (experts: CVI 0.73-1.0). Participants identified some specific areas for improvement in the next version.

Conclusions

The serious game appears to be valid. It is intended as a support tool for nursing students in the teaching–learning process and as a tool for continuing education for nurses.
Contribution of the co.LAB Framework to the Collaborative Design of Serious Games: Mixed Methods Validation Study
Authors: Jaccard Dominique , Suppan Laurent , Bielser Félicia
Published: October 2021

Background

Multidisciplinary collaboration is essential to the successful development of serious games, albeit difficult to achieve. In a previous study, the co.LAB serious game design framework was created to support collaboration within serious game multidisciplinary design teams. Its use has not yet been validated in a real usage context.

Objective

The objective of this study was to perform a first assessment of the impact of the co.LAB framework on collaboration within multidisciplinary teams during serious game design and development.

Methods

A mixed methods study was conducted, based on 2 serious game design projects in which the co.LAB framework was used. The first phase was qualitative and carried out using a general inductive approach. To this end, all members of the first serious game project team who used the co.LAB framework were invited to take part in a focus group session (n=6). In a second phase, results inferred from qualitative data were used to define a quantitative instrument (questionnaire) that was designed according to the Checklist for Reporting Results of Internet E-Surveys. Members of both project teams (n=11) were then asked to answer the questionnaire. Quantitative results were reported as median (Q1, Q3), and appropriate nonparametric tests were used to assess between-group differences. Finally, results gathered through the qualitative and quantitative phases were integrated.

Results

In both phases, the participation rate was 100% (6/6 and 11/11). Verbatim transcripts were classified into 4 high level themes: (1) influence on collaborative dimensions; (2) impact on project course, monitoring, and efficiency; (3) qualitative perceptions of the framework; and (4) influence of team composition on the use of the framework. The web-based questionnaire was then developed according to the 7 dimensions of collaboration by Burkhardt et al. In both projects, the co.LAB framework had a positive impact on most dimensions of collaboration during the multidisciplinary design and development of serious games. When all collaborative dimensions were aggregated, the overall impact of the framework was rated on a scale from –42 to 42 (very negative to very positive). The overall median score was 23 (Q1, Q3: 20, 27), with no significant difference between groups (P=.58). Most respondents also believed that all serious game design teams should include a member possessing significant expertise in serious game design to guide the development process.

Conclusions

The co.LAB framework had a positive impact on collaboration within serious game design and development teams. However, expert guidance seems necessary to maximize development efficiency. Whether such guidance can be provided by means of a collaborative web platform remains to be determined.
Supporting the Mental Health Needs of Military Partners Through the Together Webinar Program: Pilot Randomized Controlled Trial (Preprint)
Authors: Hendrikx Laura Josephine , Murphy Dominic
Published: October 2021

BACKGROUND

Despite an increased risk of psychological difficulties, there remains a lack of evidence-based support for the mental health needs of military partners.

OBJECTIVE

This study aims to investigate whether the Together Webinar Programme (TTP-Webinar), a 6-week structured, remote access group intervention would reduce military partners’ experience of common mental health difficulties and secondary trauma symptoms.

METHODS

A pilot randomized controlled trial was used to compare the TTP-Webinar intervention with a waitlist control. The sample was UK treatment-seeking veterans engaged in a mental health charity. A total of 196 military partners (1 male and 195 females; aged mean 42.28, SD 10.82 years) were randomly allocated to the intervention (n=97) or waitlist (n=99) condition. Outcome measures were self-reported measures of common mental health difficulties, secondary trauma symptoms, and overall quality of life rating.

RESULTS

Compared with the waitlist, military partners in the TTP-Webinar had reduced common mental health difficulties (P=.02) and secondary trauma symptoms (P=.001). However, there was no difference in quality-of-life ratings (P=.06).

CONCLUSIONS

The results suggest that TTP-Webinar is an effective intervention to support the mental health difficulties of military partners. This study provides promising evidence that webinars may be an appropriate platform for providing group-based support.

CLINICALTRIAL

ClinicalTrials.gov NCT05013398; https://clinicaltrials.gov/ct2/show/NCT05013398
Cytochrome P450 1B1 Overexpression in Cervical Cancers: Cross-sectional Study (Preprint)
Authors: Alshammari Fatemah O F O , Al-saraireh Yousef M , Youssef Ahmed M M , Al-Sarayra Yahya M , Alrawashdeh Hamzeh Mohammad
Published: October 2021

BACKGROUND

Current standard treatments for patients with recurrent cervical cancer are not very effective and are associated with severe toxicity. Recently, the rational approach for the discovery of new therapies for cervical cancer is based on the alterations in the molecular biology of cancer cells. One of the emerging molecular changes in cancer cells is the aberrant expression of cytochrome P450 1B1 (CYP1B1). This unique enzyme has been reported to be selectively overexpressed in several cancers.

OBJECTIVE

The aim of this study was to examine CYP1B1 expression in cervical cancers and to assess the enzyme’s relationship with several clinicopathological features.

METHODS

Immunohistochemistry was performed to examine CYP1B1 expression in 100 patient samples with cervical cancer and 10 patient samples with normal healthy cervical tissues.

RESULTS

CYP1B1 was expressed in the majority of the cervical cancer samples (91/100, 91.0%) but not in normal healthy cervical samples. The difference in the expression of CYP1B1 between healthy and tumorous cervical tissues was significant (P=.01). Moreover, the frequency of CYP1B1 expression was found to be significantly higher in patients with advanced grades of the disease (P=.03) and in patients having metastasis to the lymph nodes (P=.01). Surprisingly, there was a significantly higher expression of CYP1B1 in patients with a high prevalence of human papilloma virus 16/18 (P=.04).

CONCLUSIONS

The differential profile of CYP1B1 expression between cervical cancer tissues and normal cervical tissues suggests that CYP1B1 may be used as a target for future therapeutic exploitations.
Performance of Artificial Intelligence Imaging Models in Detecting Dermatological Manifestations in Higher Fitzpatrick Skin Color Classifications (Preprint)
Authors: Aggarwal Pushkar
Published: October 2021

BACKGROUND

The performance of deep-learning image recognition models is below par when applied to images with Fitzpatrick classification skin types 4 and 5.

OBJECTIVE

The objective of this research was to assess whether image recognition models perform differently when differentiating between dermatological diseases in individuals with darker skin color (Fitzpatrick skin types 4 and 5) than when differentiating between the same dermatological diseases in Caucasians (Fitzpatrick skin types 1, 2, and 3) when both models are trained on the same number of images.

METHODS

Two image recognition models were trained, validated, and tested. The goal of each model was to differentiate between melanoma and basal cell carcinoma. Open-source images of melanoma and basal cell carcinoma were acquired from the Hellenic Dermatological Atlas, the Dermatology Atlas, the Interactive Dermatology Atlas, and DermNet NZ.

RESULTS

The image recognition models trained and validated on images with light skin color had higher sensitivity, specificity, positive predictive value, negative predictive value, and F1 score than the image recognition models trained and validated on images of skin of color for differentiation between melanoma and basal cell carcinoma.

CONCLUSIONS

A higher number of images of dermatological diseases in individuals with darker skin color than images of dermatological diseases in individuals with light skin color would need to be gathered for artificial intelligence models to perform equally well.
Determination of Caffeic Acid in Ethanolic Extract of Spent Coffee Grounds by High-Performance Liquid Chromatography with UV Detection
Authors: Gani Michael Raharja , Istyastono Enade Perdana
Published: October 2021

We developed a method for determining the caffeic acid in spent coffee grounds. The spent coffee ground solution was prepared by blending 3 g spent coffee grounds with 60 mL ethanol/water (40/60 v/v) for 2 h on a hot plate magnetic stirrer (60 °C, 350 rpm). The mixture was filtered and the filtrate was concentrated under vacuum (60 °C) to 5 mL. The method employed a reversed-phase high-performance liquid chromatography with a UV detector. We used a Phenomenex Luna column (250 × 4.6 mm; i.d., 5 µm) under isocratic elution, and the mobile phase was acetonitrile-methanol-aqueous formic acid (10:10:80 v/v), with a flow rate of 0.9 mL/min. Analysis was performed at 324 nm. The column temperature was set at 27 °C temperature. The results showed that this method was selective for quantifying the caffeic acid in spent coffee grounds with good linearity in the range of 1.31–17.07 μg/mL. The detection and quantitation limits were 0.28 and 0.84 μg/mL, respectively. The mean intraday and interday recoveries were 83.80–95.17% and 82.16–97.40%, respectively. Intraday and interday precision expressed as the relative standard deviation (RSD) were below 7.3%. There was 0.17% ± 0.006 w/w caffeic acid in the spent coffee grounds (RSD = 3.63%, n = 3).
Preparation, Characterization, and In Vitro Hemocompatibility of Glutaraldehyde-Crosslinked Chitosan/Carboxymethylcellulose as Hemodialysis Membrane
Authors: Khabibi Khabibi , Siswanta Dwi , Mudasir Mudasir
Published: October 2021

This study aims to examine the manufacture, characterization, and in vitro hemocompatibility of glutaraldehyde-crosslinked chitosan/carboxymethyl cellulose (CS/CMC-GA) as a hemodialysis membrane. The CS/CMC-GA membrane was prepared using the phase inversion method with 1.5% CS and 0.1% CMC. The chitosan was crosslinked with glutaraldehyde in various monomers ratios, and the membranes formed were characterized by FTIR, SEM, and TGA. Furthermore, the hydrophilicity, swelling, porosity, mechanical strength, and dialysis performance of the membranes against urea and creatinine were systematically examined, and their in-vitro hemocompatibility tests were also conducted. The results showed that the CS/CMC-GA membranes have higher hydrophilicity, swelling, porosity, mechanical strength, and better dialysis performance against urea and creatinine than chitosan without modification. In addition, the hemocompatibility test indicated that the CS/CMC-GA membranes have lower values of protein adsorption, thrombocyte attachment, hemolysis ratio, and partial thromboplastin time (PTT) than that of pristine chitosan. Based on these results, the CC/CMC-GA membranes have better hemocompatibility and the potential to be used as hemodialysis membranes.
Pre-Concentration and Determination of Tetracyclines Antibiotics Residues in Water Samples Using RGO/Fe3O4 Nanocomposite as Extraction Sorbent
Authors: Ungku Abdullah Ungku Amirul Arif , Mohamad Hanapi Nor Suhaila , Wan Ibrahim Wan Nazihah , Mat Hadzir Nursyamsyila , Zaini Nurzaimah , Anis Ahmad Lutfi , Yahaya Noorfatimah
Published: October 2021

Existing methods used in tracing Tetracyclines' antibiotics (TCAs) residues which pose serious environmental problems, consume high amounts of organic solvents, are time-consuming, and are relatively expensive. A simple and effective magnetic solid-phase extraction (MSPE) based on reduced graphene oxide/magnetite (RGO/Fe3O4) nanocomposite sorbent was successfully developed for preconcentration and extraction of TCAs residues from water samples. The analytes were determined by high-performance liquid chromatography with a diode-array detector (HPLC-DAD). The synthesized nanocomposite was characterized using Fourier-transform infrared spectroscopy (FTIR), X-ray diffractometry (XRD), and field emission scanning electron microscopy (FESEM). Sample pH, amount of adsorbent, sample volume, extraction time, desorption time, and desorption solvent were evaluated and optimized. Under optimized conditions, the method demonstrated good linearity over the concentration range of 0.05–1.0 mg L–1 with the coefficient of determination (R2) ≥ 0.9978. Limit of detection (LOD) and limit of quantification (LOQ) were 0.006–0.011 mg L–1 and 0.019–0.036 mg L–1, respectively. The accuracy and precision of the developed method were proven by good analyte recovery (89.77–106.33%) and acceptable precision with relative standard deviation, RSD ≤ 5.54%. The results showed that magnetic solid RGO/Fe3O4 could be a suitable adsorbent in the preconcentration and extraction of TCAs in water samples.
Novel Bis Maleimide Derivatives Containing Azo Group: Synthesis, Corrosion Inhibition, and Theoretical Study
Authors: Dhaef Hawraa Kareem , Al-Asadi Rafid Humaidan , Shenta Ashwaq Abood , Mohammed Mohammed Khalaf
Published: October 2021

Novel derivatives of heterocyclic azo compounds have been synthesized through a free catalyst reaction. The structures of the synthesized compounds were confirmed by using different techniques such as 1H-NMR, 13C-NMR, and mass spectroscopy. The prepared derivatives were evaluated as corrosion inhibitors for mild steel after the inhibitory performance toward mild steel in 0.1 M HCl solution. The prepared derivatives, i.e. (1,1'-(((1E,1'E)-1,4-Phenylenebis(diazene-2,1-diyl))bis(4-methyl-3,1-phenylene))bis(1H-pyrrole-2, 5-dione)) 1 and (1,1'-(((1Z,1'Z)-(Oxybis(4,1-phenylene))bis(diazene-2,1-diyl)) bis(4-methyl-3,1-phenylene))bis(1H-pyrrole-2,5-dione)) 2 showed inhibition efficiency 89.22% and 91.30%, respectively at concentration 1 × 10–3 M. The isotherm adsorptions of these derivatives were found to obey Langmuir model. Furthermore, Density functional theory was used for theoretical estimation of the HOMO, LUMO, and other chemical quantum parameters. The results indicated that the synthesized derivatives displayed a corrosive inhibitory property in which derivative 2 was more effective than derivative 1. In addition, the theoretical results were in agreement with the experimental data.
Influence of Cobalt Substitution in LaMnO3 on Catalytic Propylene Oxidation
Authors: Vaz Teotone Inas Mariano , Gurav Sridhar Maruti , Salker Arun Vithal
Published: October 2021

Perovskite-type structures LaBO3 with the compositions of LaMn1-xCoxO3 (x = 0.0, 0.3, 0.5, 0.7, and 1.0) were synthesized at 800 °C by a modified co-precipitation precursor technique for total oxidation of propylene, as a model test of the hydrocarbon oxidation reaction. Details concerning the evolution of the crystal structure, morphology, and crystallite size were performed by X-ray diffraction (XRD), Thermo Gravimetry Analysis (TGA)/Differential Scanning Calorimetry (DSC), Fourier Transform Infra-Red (FTIR), Atomic Absorption Spectroscopy (AAS), Scanning Electron Microscopy (SEM), and Electron Spin Resonance (ESR) techniques. All compositions were identified to be single-phase and are indexed to rhombohedral structures. TG/DSC technique evidenced a temperature of 330 °C needed for the precursor as the start point and 800 °C completion for perovskite phase formation. Slight distortion in XRD diffraction peaks was observed on substituting manganese with cobalt in B-site, and new peaks emerged. An attempt has been made to understand the effect of the B-site substitution of Co3+ ions in the lattice of LaMnO3 and their influence on catalytic total propylene oxidation efficiency. These compounds show a considerable increase in the activity of propylene oxidation to carbon dioxide and water and could be explored for hydrocarbon pollution control.
The Apothecary of Poetry: The Healing Power of Verse
Authors: Eterovic Nikola Niksa
Published: October 2021

The Apothecary of Poetry is an interdisciplinary project by author Nikola Niksa Eteorvic that came to life in 2013. The first APOTHECARY OF POETRY that treats patients with verse. In this text, the reader will get acquainted with some possibilities and aspects of the Apothecary of Poetry and its working process. How to use poetry, both already existing poetry and poetry created with the users of AP, is an important aspect of this text. The philosophy of verse, substance—selfhood and action, are reflected in the work of the Apothecary of Poetry in various ways. Poetry is medicinal, poetry is a medicine that you come to get at the Apothecary of Poetry. Poetry is the closest reflection of our existence.
On the Integration of Ideological and Political Education into Specialized Courses in Chinese Universities: A Case Study of English Foundation Course
Authors: Saisai Huang
Published: October 2021

This paper provides a detailed introduction to the new trend of Ideological and Political Education (IPE) in Chinese universities, i.e. integrating IPE into specialized courses. It draws on a thematic analysis of documents from Ministry of Education (MOE) and States sources. The paper reveals the principles and practices of integrating IPE into specialized courses in Chinese universities. Also, the course English Foundation Course from Foreign Language Schools of Zhejiang University of Finance and Economics Dongfang College is exemplified to show the whole process of integration.
Building scientific knowledge based on the solution of clinical cases: A contemporary learning process
Authors: Marques EM , Munhoz FC , Cunha ER
Published: October 2021

The construction of scientific knowledge based on the solution of clinical cases, also called problem-situation or case study, is a contemporary methodology, centered on the student, problematizing, teaching-learning, which allows to know the previous knowledge of the group in the face of the presented situation, as well as identifying learning needs, building new meanings and knowledge, in addition to developing specific skills for self-learning. Strategically, it is the insertion, during a course, of a social material (texts, audios, printed matter, videos), whose analysis and discussion allow to contextualize the theoretical content. This work aims to present an experience in the construction, application and evaluation of clinical cases aimed at students in the fifth period of the dentistry course at Itpac - Porto Nacional in 2020. Clinical cases were previously screened by the teacher of endodontics at the multidisciplinar clinic at Itpac - Porto Nacional and presented to students in the classroom. The students were instructed to organize themselves in groups, a time of 1 hour was established for discussion of clinical cases and websites, scientific articles and books were made available to assist in solving the proposed activity. After the end of the established time, each group presented the diagnosis of each clinical situation presented. Based on this experience, it is possible to conclude that the use of clinical cases as a pedagogical practice brings students closer to the social reality and leads them to build networks of knowledge, making them active subjects in the learning process, without renouncing the depth and specificity knowledge that a dental student needs to develop.
THE THE FIRST DOCUMENTED PREY ITEMS FOR Bothrops medusa (STERNFELD, 1920)
Authors: Schramer Tristan David
Published: October 2021

The Venezuelan forest pitviper (Bothrops medusa) is an endangered viperid endemic to the central range of the Cordillera de la Costa in Venezuela. Little is known regarding its natural history. We examined the stomach contents of museum specimens housed in the University of Illinois Museum of Natural History Herpetology Collection and report the first prey items for the species. The arboreal habits of both prey items support the notion that B. medusa may be semi-arboreal. This exposes the need for further studies on this rare viperid and showcases the value of natural history collections for studying endangered species.
Four cases of prey-predator interaction (anuran-snake) through their geographical distribution
Authors: Aguilar-López José Luis
Published: October 2021

The biotic interaction prey-predator between one anuran species and one snake species, in some cases have been reported just in one geographical location, and in other cases have been reported several records through the geographical distribution of both interacting species. In this study we report four cases of anurans predation by snakes in different geographical location to the previous records. The previous and new records suggest that the biological interaction prey-predator between two species is maintained regardless of the geographical location and elevation. The consequences of these kind of biotic interactions for the predator and prey requires further study.
Análisis mediante dinámica de fluidos computacional de la conducción de calor de un elemento combustible del reactor nuclear TRIGA MARK III
Authors: Rojas Valdez David , López Rebollar Boris Miguel
Published: October 2021

La conducción de calor de un elemento combustible del reactor nuclear TRIGA MARK III fue simulada usando el método de dinámica de fluidos computacional (CFD). El objetivo fue obtener los perfiles de temperatura y de la conducción de calor que se generan en un elemento combustible nuclear bajo diferentes niveles de potencia térmica de operación del reactor (0.5, 0.8 y 1 MW). Actualmente no se han desarrollado investigaciones que aborden la simulación del proceso de la conducción de calor en un elemento combustible de reactores tipo TRIGA mediante CFD, por este motivo, la metodología estableció una validación de los resultados obtenidos mediante CFD, comparándolos con los datos reportados en el informe de seguridad del reactor simulados con RELAP5 (Reactor Excursion Leak Analysis Program 5) (ININ, 2008), con el análisis se obtuvo una variación de 3.36% en el perfil radial de temperatura. Los resultados de este trabajo muestran el comportamiento térmico en el perfil radial del elemento combustible el cual varía según la potencia térmica de operación del reactor, ésta también influye en la distribución axial de calor en el elemento combustible. Se concluyó que las simulaciones realizadas mediante CFD muestran un buen acuerdo con los valores obtenidos utilizando herramientas computacionales especializadas en el análisis de sistemas nucleares. Por tal motivo, los resultados obtenidos en el presente trabajo proporcionaran fundamentos para realizar análisis posteriores del monitoreo de los dispositivos que componen el reactor, como: la piscina de enfriamiento, barras de control, elementos de grafito y elementos combustibles con diferente posición en el núcleo, además de incluir los procesos que se generan durante la operación del reactor, tales como, el enfriamiento del núcleo, el funcionamiento del intercambiador de calor y el de la bomba difusora.
Neuroimaging referral for reassurance in evaluation of headache with low-risk features
Authors: Fernandez Omar E.
Published: October 2021

A clinical decision report using:

Howard L, Wessely S, Leese M, et al. Are investigations anxiolytic or anxiogenic? A randomised controlled trial of neuroimaging to provide reassurance in chronic daily headache. J Neurol Neurosurg Psychiatry. 2005;76(11):1558-1564. https://doi.org/10.1136/jnnp.2004.057851

for a patient with daily headache.
Using a single tablet regimen of darunavir, cobicistat, emcitrabine, and tenofovir alafenamide in virally suppressed HIV-1 patients is an adequate treatment option for controlling HIV
Authors: Kathuria Priya
Published: October 2021

A clinical decision report using:

Orkin C, Molina JM, Negredo E, et al. Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial. Lancet HIV. 2018;5(1):e23-e34. https://doi.org/10.1016/S2352-3018(17)30179-0

for a patient with viriologically suppressed HIV-1.
Оболочечные структуры: генезис, материалы и подвиды
Authors: Кривошапко Сергей , Алборова Лана , Мамиева Ираида
Published: October 2021

В статье рассматриваются стилевые течения примени­тельно к тонким оболочкам и оболочечным структурам. Причём, вышесказанное не касается технологических обо­лочек и пространственных структур, таких как трубопроводы, подземные туннели, машиностроительные изделия и т.д. Все рассмотренные стили проиллюстрированы конкретными построенными объектами. Установлено, что всего при про­ектировании оболочечных структур архитекторами было использовано 26 архитектурных стилей и стилевых направ­лений. Для интересующихся более подробной информацией приводится обширная библиография.
Estructura, diversidad y endemismo de la flora del relicto Los Lanches del bosque montano Las Palmas, Cajamarca, Perú
Authors: Burga-Cieza Alexis Michael , Burga Cieza Jans , Iglesias-Osores Sebastian , Alcalde-Alfaro Victor William , Martínez-Sovero Gustavo , Dávila-Estela Luis , Villena-Velásquez Jim Jairo
Published: October 2021

Los bosques montanos albergan especies endémicas valiosas, a pesar que no se conoce a detalle su diversidad. Siendo el objetivo caracterizar la estructura, diversidad y endemismo del relicto Los Lanches del bosque montano Las Palmas distrito de Conchan, Chota, Cajamarca, Perú. Se evaluaron siete parcelas de 1 000 m2 para el estrato arbóreo y en parcelas de 100 m2 y 25 m2 para la regeneración natural. La distribución horizontal refleja una “J” invertida. Weinmannia elliptica (16,63 %) y Hedysomum scabrum (10,27 %) presentaron índices de valor de importancia altos. El 20 % de especies persisten en los tres estratos. De la regeneración natural las especies más importantes son Hedyosmum scabrum (27,79 %) y Palicourea amethystina (14,77 %). Las especies con alto valor de importancia ampliado Hedyosmum scabrum (19,24 %) y Weinmannia elliptica (11,44 %). Las familias más abundantes fueron Lauraceae con cuatro especies, y tres especies la Myrtaceae y Melastomataceae. Se obtuvo un coeficiente de mezcla de 0,033, el índice de Simpson (0,89) indicó alta diversidad, al igual que el índice Shannon-Wiener (2,68). La Brachyotum coronatum y Cyathea caracasana, se encuentran en estado vulnerable. La Axinaea nitida en estado de preocupación menor y la Ocotea jumbillensis en peligro.
La preocupación ambiental en estudiantes de educación superior de Madre de Dios, Perú
Authors: Estrada Araoz Edwin Gustavo , Huaypar Loayza Karl Herbert , Mamani Uchasara Helen Juddy , Velasquez Giersch Libertad , Gallegos Ramos Néstor Antonio
Published: October 2021

Muchas personas han incrementado su nivel de preocupación por el ambiente después de percibir los problemas ecológicos que enfrenta nuestro planeta y las consecuencias que provoca en nuestra sociedad. En ese sentido, la presente investigación tuvo como objetivo analizar la preocupación ambiental de los estudiantes del Instituto de Educación Superior Pedagógico Público Nuestra Señora del Rosario de Madre de Dios, Perú. El enfoque fue cuantitativo, el diseño no experimental y el tipo, descriptivo transversal. La muestra fue conformada por 151 estudiantes a quienes se les aplicó la Escala de Preocupación Ambiental, instrumento con adecuado nivel de confiabilidad y validez. Se determinó que los estudiantes se caracterizan por presentar una moderada preocupación ambiental y se halló que dicha variable se asociaba de manera significativa con algunas variables sociodemográficas y académicas como el sexo, el grupo etario, el año de estudio y el nivel socioeconómico. Se concluyó que es necesario considerar al componente medioambiental como eje transversal en las actividades académicas, articular aspectos teóricos y prácticos en el desarrollo de las sesiones de aprendizaje e involucrar a los actores educativos para que exista una mayor preocupación por el ambiente y una actitud favorable hacia su conservación.
Occult bacteremia in children with simple febrile seizure in the post-pneumococcal conjugate vaccine era
Authors: Yoon Gwan Shik , Chung Hyun Jung , Byun Young Hoon , Kim Min Jung , Park Soo Hyun , Paek So Hyun , Kim Ok Jun , Kwon Jae Hyun
Published: October 2021

Purpose: The authors aimed to investigate the utility of blood culture (BC) for children with simple febrile seizure (SFS) in the emergency department (ED) in the post-10/13-valent pneumococcal conjugate vaccine (PCV) era. Methods: This study was performed at the ED of a tertiary care university-affiliated women and children’s hospital, and involved 3,237 previously healthy children aged 6-60 months who visited the ED with SFS from January 2013 through December 2017. The SFS was defined according to the International Classification of Diseases, 11th Revision codes related to seizure. The children were divided into 2 groups according to the vaccination rates of the period of their visit: the 70-PCV (70%, 2013-2014) and 97-PCV (97%, 2015-2017) groups. The primary outcome was the yield, defined as a true positivity of BC. In addition, we collected information on baseline characteristics, ED length of stay, inflammatory biomarkers, and ED outcomes. Results: Of the 1,578 children with SFS who underwent BC, 1,357 belonged to the 97-PCV group. The median age of the study population was 22 months (interquartile range, 16.0-30.0), and 935 children (59.3%) were boys. Of the 41 children (2.6%) with positive BC results, 3 had the yield (0.2%): Staphylococcus aureus in 2 children and Streptococcus pneumoniae in the other. All 3 children belonged to the 97-PCV group. There were 38 contaminated BCs (2.4%; 95% confidence interval, 1.6%-3.2%). The 97-PCV group showed a shorter median ED length of stay (166.0 minutes [108.0-279.5] vs. 143.0 [109.5-209.5]; P = 0.010) and a lower rate of hospitalization (39.4% vs. 12.8%; P < 0.001). No differences between the 2 groups were found in the baseline characteristics and biomarkers.Conclusion: This study suggests a low utility of BC in previously healthy children with SFS in emergency settings in the post-10/13-valent PCV era.
Antioxidant and Antibacterial Activity of Yellow Wood (Coscinium fenestratum) Fruits Peel from East Kalimantan
Authors: Kustiawan Paula Mariana , Arbainsyah Arbainsyah , Setiawan Irfan Muris
Published: October 2021

Background: Yellow wood (Coscinium fenestratum) is one of the typical forest plants of East Kalimantan. The hallmark of this plant is the roots, stems and the fruits pulp have a yellow color. There have been many studies on its use and potential in treating liver disease. However, there is limited research about the use of their fruits peel. Objectives: The purpose of this study was as an initial screening of the antioxidant and antibacterial activity from yellow wood (Coscinium fenestratum) fruits peel. Material and Methods: The yellow wood fruits peel was extracted using methanol solvent to obtain the MeOH extract of their fruits peel. The DPPH test was carried out to determined its antioxidant activity (25,50 and 100 ppm). The agar well difusion method was carried out to determined its antibacterial activity. Phytochemical tests are also carried out to determined the secondary metabolites of that fruits peel. Results: The results of the phytochemical test showed that the fruits peel contained alkaloids, flavonoids, carbohydrates, and tannins, but there were no terpenoids or steroids. The fruits peel has an antioxidant activity (58%) at 100 ppm concentration. While the antibacterial test showed strong inhibition at 100 ppm concentration on S. mutans, S. aureus, P. acne and E. coli bacteria. Conclusions: The fruits peel of the yellow wood has compounds that have strong antibacterial activity and medium antioxidant activity.
The role of institutional shareholders in the relationship between unconditional conservatism and earnings management
Authors: Casciello Raffaela , Maffei Marco , Meucci Fiorenza
Published: October 2021

This study investigates whether and how institutional shareholders affect the relation between unconditional conservatism and earnings management. We analyze the relation between unconditional conservatism and accrual-based earnings management and the relation between unconditional conservatism and real earnings management, focusing on the role of the institutional shareholders variable in these two relations. First, we find evidence of positive (negative) relations between unconditional conservatism and accrual-based (real) earnings management. Second, we demonstrate that the presence of institutional shareholders has a mitigating (amplifying) impact on the relation between unconditional conservatism and accrual-based (real) earnings management. This study contributes to enrich the previous literature in two ways. First, it extends the strand of research on the relation between accounting conservatism and earnings management (Garcìa Lara, García Osma, & Penalva, 2020; Chen, Hemmer, & Zhang, 2007; Gao, 2013), focusing on unconditional conservatism since it is less prevalent than conditional conservatism in previous literature (Ruch & Taylor, 2015). Second, it extends the strand of research on the impact of institutional ownership on accounting practices (Farooq & El Jai, 2012; Sakaki, Jackson, & Jory, 2017), highlighting the role of the institutional shareholders in the relation between unconditional conservatism and earnings management
Effect of Zn content on corrosion behavior of Mg-Y-Zn alloys
Authors: Shi Y. , Liu X.-Q. , Liu Z.-L. , Xie H.-J. , Wang Y.-H. , Li J.
Published: October 2021

The microstructure, corrosion behavior, and electrochemical behavior of as-cast Mg-4Y-xZn (x=1,2,3,4 wt.%) are studied by SEM, weight loss and electrochemical tests. Mg12YZn (X), Mg3Y2Zn3 (W) and Mg24Y5 constitute the phase composition system of the alloy. When Zn content is 1 wt.%, all tests reveal that alloy has the optimal corrosion performance. The second phase in these alloys, due to their nobler nature than ?-Mg, exists as a cathode during the corrosion process, so that ?-Mg preferentially occurs corrosion to accelerate the formation of corrosion pits. After soaking in 3.5 wt.% NaCl solution for some time, the stability of the W phase changed, and gradually dissolved, which was finally removed by chromic acid used for removal of corrosion products. In addition, X phase can be used as an anode in the micro-galvanic cells formed with W phase to reduce the corrosion rate of ?-Mg and thus improve the corrosion performance of the alloy.
Toxic elements in children’s crayons and colored pencils: Bioaccessibility assessment
Authors: Djogo-Mracevic Svetlana , Razic Slavica , Trisic Jelena , Mitrovic Nikola , Djukic-Cosic Danijela
Published: October 2021

Crayons and colored pencils for children may contain toxic elements (TEs) exhibiting potential risk for children?s health including cognitive development, after their ingestion, through mouthing and chewing and eventually, their accumulation. The aim of this study was to determine total content of As, Pb, Cr, Cd, Ni and Sb and estimate their bioaccessibility conducting artificial saliva extraction. Sixty samples of colored pencils and crayons from 10 manufacturers were analyzed. Microwave acid assisted digestion followed by inductively coupled plasma optical spectroscopy (ICP-OES) was performed for determination of total content of TEs. Simulation of extraction by artificial saliva was applied to get more reliable data when bioavailability is concerned. The total concentrations of TEs were higher in colored pencils than in crayons and their maximum levels were: 5.78, 9.36, 9.97, 0.615, and 6.63 mg kg-1 for As, Pb, Cr, Cd and Ni, respectively. Concentration of Sb was below the detection limit for all investigated samples. This study showed that concentration of As and Pb in several samples did not comply with European Union regulative. Bioaccessibility study showed the high degree of leaching of Cr and As from pencils, but regardless of extracted portions, concentrations of selected investigated TEs were below allowed levels.
Numerical simulation method of marine oil-water separation
Authors: Li Yunfeng , Li Yuting
Published: October 2021

In order to reduce the frequency of marine environmental pollution accidents,
marine oil-water separation numerical simulation method is developed. The
oil-water separation hydrocyclone is used for emergency treatment to deal
with the marine surface oil pollution, and the oil-water separation optimal
control parameter calculation method based on the mathematical model of the
flow field is used to simulate the oil-water separation performance of the
device. The simulation results show that when the split ratio is 4.1%, the
inlet pressure is 0.15MPa, the overflow pipe diameter is 3 mm, the oil
droplet size is 101, and the large vertebral angle is 27, the hydrocyclone
has good separation performance. Under these conditions, this method can be
used as a reference method for dealing with oil spills in the ocean and has
certain application value.
Design of performance evaluation model for warm mix recycled asphalt pavement based on fuzzy decision algorithm
Authors: Wang Shuguang
Published: October 2021

In order to improve the accuracy and comprehensiveness of asphalt pavement
performance evaluation, a performance evaluation model based on warm mixed
recycled asphalt pavement was proposed. Based on the evaluation indexes such
as pavement quality, pavement damage, pavement structure bearing capacity,
pavement skid resistance, pavement rutting and pavement comprehensive
performance, the performance evaluation system of warm mixed recycled
asphalt pavement was established. According to the standard numerical
characteristics of asphalt pavement performance evaluation index, the
subjection function of asphalt pavement performance is constructed. The
trapezoidal and semi-trapezoidal distribution functions are obtained, and
the membership functions of each distribution section are established.
Considering the comprehensiveness, fuzziness and complexity of the
evaluation, the fuzzy decision algorithm is introduced to determine the
interval weight of each index, and the structure is quantified according to
the evaluation index. The membership function and fuzzy subset are
established. The evaluation standard and evaluation level are determined
based on fuzzy relation matrix, and the pavement performance is evaluated.
The experimental results show that the evaluation results of this model are
accurate and reliable, and it has obvious advantages in application.
Numerical simulation of heat dissipation of surface mounted permanent magnet synchronous hub motor
Authors: Leng Shuai , Jin Liqiang
Published: October 2021

Due to the insulation aging, demagnetization and other problems of the
permanent magnet and insulating material in the permanent magnet
synchronous hub motor under high temperature, the numerical simulation of
the heat dissipation of surface mounted permanent magnet synchronous hub
motor is proposed. According to the heat transfer of hub motor, the effect
degree of heat conduction, heat convection and heat radiation is obtained,
the heat transfer coefficient of each part is calculated, and the influence
of motor insulation material on temperature rise is analyzed. The
experimental results show that the heat dissipation of hub motor under
natural cooling condition is poor, and the internal oil cooling method can
effectively improve the heat dissipation of hub motor and reduce the
temperature difference. When operating at high speed, this reduces the
potential safety hazard.
Parameter optimization of anti crystallization flocking drainage pipe based on flow field distribution characteristics
Authors: Liu Shiyang , Xiang Kun , Gao Feng , Zhang Xuefu , Li Yun , Omar Khairi
Published: October 2021

The crystal plugging of tunnel drainage pipe seriously affects the safe and
normal use of the tunnel. In order to obtain the mechanism of flocking
drainage pipe anti crystal plugging based on the characteristics of flow
field distribution, numerical simulation was used to optimize the parameters
of flocking drainage pipe. The results show that: with the existence of
fluff, the velocity in the lower part of the drainage pipe decreases by
about 50%, and the velocity in the upper part increases by about 25~50%.
With the increase of the length of fluff, the velocity funnel between
fluffs gradually increases, the velocity distribution at the bottom of the
funnel is basically unchanged, and the velocity in the upper part gradually
increases. The velocity in the upper part of the flocked drainage pipe
fluctuates above the fluff to a certain extent. The flow velocity in the
lower part of the drainage pipe forms a flow velocity ladder in the
longitudinal direction of the villus, and the width of the ladder is about
2/3 of the longitudinal spacing of the villus. The optimized parameters of
3-D flow field of flocked drainage pipe are helpful to the further
improvement of indoor test, and provide theoretical basis for the mechanism
of preventing crystal blockage of flocked drainage pipe.