bluuebunny/crossref_metadata_2025 huggingface dataset:
Life Beyond A Breast Cancer Diagnosis: Women's Constructions of Breast Cancer in Online Media
Authors:   , Welsby Drew
Published: April 2023

Breast cancer is the most common form of cancer for women in Aotearoa New Zealand and eighty-five percent of women who are diagnosed with breast cancer in Aotearoa will live longer than 10 years after diagnosis. After a breast cancer diagnosis, women must negotiate their new lives and identities as ‘cancer survivors’, or someone who has had cancer, drawing on forms of support and information to make meaning of their experiences. Previous research has identified that online media spaces are used by women with a breast cancer diagnosis for information, support, validation and reassurance. Although, there is minimal research investigating how women construct and negotiate life with a breast cancer diagnosis online. The main objective of this research was to explore how women make meaning of life with a breast cancer diagnosis within online breast cancer media texts. Existing online breast cancer narratives were collected from two community organisation websites and reflexive thematic analysis was used to identify higher order themes. This research adopted a social constructionist epistemology and took up a neoliberal and postfeminist theoretical lens to inform theme identification. The findings demonstrated that women drew on neoliberal and postfeminist discourses of individual responsibility, control, exemplified empowerment, idealised femininity and ‘good cancer survivor’ discourse to make meaning of their life after a breast cancer diagnosis. Women constructed their selves and other women as individually responsible for engaging in self- surveillance and staying in control of their cancer, positioning control as desirable as suggested through ‘good cancer survivor’ discourse. Women also drew on postfeminist ideals of hetero femininity and constructed breast cancer as disruptive to their ability to take up culturally desirable and idealised feminine identities. However, women contradicted this by positioning themselves as individually responsible for being “unable” mothers. Most women tended to put in work to achieve an idealised physical feminine appearance, whereas some took up alternative discourses of femininity to make sense of their appearance in the context of cancer. The implications of this research suggest that while online media spaces may be used as a source of information and support by women with a breast cancer diagnosis, they also sustain dominant breast cancer survivorship discourses which tend to dismiss the often difficult realities of living with a breast cancer diagnosis. This may have negative consequences for women’s psychosocial wellbeing, as they are constantly presented with idealised forms of cancer survivorship. Overall, there is a need to develop alternative discourses of breast cancer survivorship which are in alignment with the realities of women with a breast cancer diagnosis. A shift in dominant discourses of breast cancer survivorship should have a positive impact for women with a breast cancer diagnosis by legitimising their experiences.
In-Between Hope and Despair: An urban experiment for Palestinians in the Occupied Territories - Ramallah, West Bank
Authors:   , Chu-Fong Melissa
Published: April 2023

This thesis aims to design an urban experiment for a Palestinian community in the Occupied Palestinian Territories (OPT) in the hope to reclaim their identity through the ongoing conflict. Perspectives taken from Palestinians will provide the research background towards the interpretation of architecture that should be placed in the right context in history. Palestinians in Israel are restricted to many rights, including the lack of urban initiatives due to the occupation efforts of the Israeli State.

There is a continuing struggle to understand how culture should be expressed in Palestinian architecture due to the conflict and stagnation of rights. This remains as Palestinians have been disengaged with their identities due to the forceful occupation and volatile environments that surround them in the OPT. The lack of support in urban development marks their fragile existence within the country that previously contained a rich cultural heritage built from centuries of habitation. Improvement towards a brighter future can be looked at from a ground up perspective by engaging with first-hand voices and experiences, which could be used to transform the expectations of the urban fabric.

This thesis proposes that a definition of Palestinian identity and culture during a time of conflict should be considered to create a framework for design experiments. It argues that to provide a sufficient design experiment, ideas should be principled by understanding the background of the Palestinian exodus and how this continuous conflict has influenced the perceptions of their identities.

The design outcome of this thesis aims to project narratives from the last decades of life under occupation to inspire the liberation of the Palestinian community and to serve as a reminder that history imprints itself in architecture.

The architectural experiments should seek longevity and respond to integrating itself through urban boundaries and quality living spaces.

This research also aims to offer a definition for the way marginalised communities are approached by prioritising cultural identity to shift power in architecture towards the community it represents. It has applications for future contexts surrounding cultural approaches towards displaced communities and encourages design investigations to start at ground level.
Leakage Power Canceling Module with a Negative Capacitor for a Circulator’s Isolation
Authors: Ngo Tan-Binh , Do Quang-Huy , Yoon Sang-Woong
Published: April 2023

In this study, we developed a leakage power canceling module (LPCM) incorporating a negative capacitor (NCAP). The NCAP provided the circulator with a wide bandwidth, rendering it suitable for retrodirective short-range wireless power transfer applications. The proposed LPCM consisted of a directional coupler, a hybrid coupler, and a low-pass filter network with an NCAP that exhibited the frequency response required to realize leakage power cancellation from the transmitter output to the receiver input. The two couplers were fabricated in an FR4 printed circuit board, and the NCAP was implemented using Samsung LR6LP 65 nm RF CMOS IC technology. The NCAP chip provided a capacitance of -2 pF and consumed a DC voltage and current of 3 V and 13 mA, respectively. The size of the fabricated LPCM was 41 mm × 37 mm. The application of the proposed LPCM was demonstrated with a commercial circulator. The S-parameter measurements indicated that the leakage cancellation was 20‒46 dB at a frequency range of 2.29–2.515 GHz. The bandwidth was defined considering a leakage cancellation of more than 20 dB, and the actual and fractional bandwidths were 222 MHz and 9.25%, respectively.
Simple Dual-Feed Dual-Circular Polarization Antenna with High Isolation
Authors: Choi Sang Won , Sung Youngje
Published: April 2023

A dual-feed antenna system with circular polarization (CP) diversity and high isolation is proposed in this paper. The proposed antenna consists of two bent monopole antennas and an isosceles triangular partial GND on a single layer. To simply design an antenna with dual-feed dual-CP characteristics, CP bandwidth (BW) is optimized based on a single antenna. The proposed antenna is structurally different from conventional antennas in three ways. Structural asymmetry is realized by bending the shape of the antenna and moving the position, and thus good CP characteristics are obtained. The feeding structure is changed from a linear type to a meander type. As a result, a single monopole antenna has a CP BW of 36%. Next, an antenna system with dual-CP characteristics is introduced by implementing two monopole antennas on a single layer. In this structure, the resonant frequency is controlled by the antenna geometrical parameters, and the null frequency at S21 is controlled by the distance between the two antennas. The measured results show that the CP BW of the proposed antenna is 40.6% (1.51–2.28 GHz). The measured isolation is below -20 dB within the operating BW.
UHF-Printed Monopole Filtenna for Partial Discharge Detection with LTE Signal Suppression
Authors: Choi Junmo , Park Seungyong , Lee Jisu , Jung Kyung-Young
Published: April 2023

External partial discharge (PD) sensors for the ultra-high frequency (UHF) method are widely used to detect the PD signals in high-voltage power equipment for ease of installation and maintenance. However, conventional external PD sensors detect not only PD signals but also LTE signals; thus, a microwave filter is usually employed. In this work, a UHF filtering antenna (filtenna) is proposed as the external PD sensor to detect PD signals and simultaneously block LTE-band signals. The proposed UHF filtenna is the printed monopole antenna with a built-in interdigital bandpass geometry, which is selected for its compact size. Measurement results show that the proposed UHF-printed monopole filtenna operates adequately in the frequency range of 1 GHz to 1.6 GHz and simultaneously blocks LTE signals significantly.
A Novel Compact Ultra-Wideband Frequency-Selective Surface-Based Antenna for Gain Enhancement Applications
Authors: Din Iftikhar Ud , Ullah Waheed , Abbasi Nisar Ahmad , Ullah Sadiq , Shihzad Waleed , Khan Bilawal , Jayakody Dushantha Nalin K.
Published: April 2023

This article presents a compact ultra-wideband (UWB) circular monopole antenna with a frequency-selective surface (FSS) for gain enhancement. The proposed antenna has a circular patch with circular cuts at the edges and is excited by a microstrip feed. The bottom plane is truncated and further modified by two triangular cuts at the sides and one rectangular cut in the middle to improve the radiation characteristics of the UWB antenna. The antenna is designed on an FR-4 substrate with a thickness of 1.6 mm, a relative permittivity of 4.3, and planner dimensions of 30 mm × 30 mm. To improve the proposed antenna’s gain, an FSS is designed that consists of periodic unit cells of metal printed on the upper layer of an FR-4 substrate with dimensions of 0.11λ × 0.11λ at the lowest operating frequency of 3.3 GHz. The FSS shows a very low transmission coefficient and linearly reducing reflection phase with increasing frequency over a frequency range of 3.3–10.8 GHz. The gain of the proposed antenna is increased from 3 dB to 8.1 dB at 9 GHz by placing the antenna on the FSS. Moreover, the prototype of the proposed antenna is fabricated, and the experimental results are measured, which show close agreements with simulated results. The FSS-based antenna has directional radiation patterns, making it a potential candidate for ground-penetrating radar and UWB applications.
SUBJECTIVE EXPERIENCES OF PERFORMANCE AND SATISFACTION IN THE PROCESS OF A MIXED LEARNING FORMAT
Authors:   Russian State University for the Humanities, Kiseleva Ekaterina A. , Komissarova Kristina S. ,   Russian State University for the Humanities
Published: April 2023

The article considers the relationship of the subjective assessment indicators for the results of learning in a mixed format, satisfaction with the process of mixed learning with awareness and tolerance to uncertainty in students of different age groups. The results showed that there was no connection between the subjective assessment of learning in a mixed format and tolerance to uncertainty, as well as between satisfaction with the process of mixed learning and awareness. Mindfulness is associated with a subjective assessment of learning outcomes, whereas interpersonal tolerance to uncertainty is associated with the perception of the variability of mixed learning. The majority of respondents demonstrated high levels of satisfaction with the mixed learning format. The study found a connection between awareness and satisfaction with the results of learning in a mixed format, which is associated with the fact that the resource of awareness helps to adapt more easily in the learning process. The flexible model of mixed education combined with high awareness allows to realize the individual educational needs of students. Awareness helps to better understand the own changes, in particular, the formation of expertise in the chosen field. The relationship between satisfaction with the process of mixed learning, characterized by variability, and interpersonal tolerance to uncertainty is revealed. Such a connection indicates rigidity in the perception of interpersonal relationships, which is a factor in the formation of discomfort due to the learning forms variability
PROACTIVE COPING AND UNCERTAINTY TOLERANCE IN PRE-RETIREES WITH DIFFERENT LEVELS OF HARDINESS
Authors:   Russian Academy of Sciences Institute of Psychology, Emel’yanova Tat’yana P. , Vikent’eva Eva N. ,   Financial University under the Government of the Russian Federation
Published: April 2023

The article presents a study of proactive coping and uncertainty tolerance in Pre-retirees with different levels of hardiness. The purpose of the study focused on the level of hardiness of Pre-retirees and on revealing preferred strategies for proactive coping and tolerance for uncertainty in their relationships. Approaches to the study of the characteristics of pre-retirement age, the phenomenon of hardiness, and the factors that determine it are analyzed. It is noted that hardiness is a valid predictor of mental and somatic health, subjective well-being and labor productivity. The article presents the results of a study of respondents of pre-retirement age (N=300) using the methods “Screening version of the hardiness test”, “Tolerance to uncertainty”, “Proactive coping”. The results show that respondents have the most pronounced proactive coping strategies such as proactive coping, preventive coping, and seeking emotional support. It was found that in the subgroup of respondents with higher hardiness, the median preference for the three proactive coping strategies is higher than in the subgroup with low hardiness. Moreover, the most tangible difference in the level of medians was found in the “Search for emotional support” strategy. Such a result may indicate that people with hardiness see, first of all, in their close environment a resource of their ability to withstand adverse life circumstances. Regarding the role of tolerance for uncertainty, it was shown that a sense of control over the situation and the possibility for clear, unambiguous interpretations and forecasts of the development of the situation are associated with hardiness. It is noted that respondents with different levels of hardiness showed the greatest differences in the affective component of tolerance for uncertainty
PERSONAL CHARACTERISTICS OF MIDDLE-AGED PEOPLE WHO UNDERWENT CAREER SHIFT
Authors:   Russian State University for the Humanities, Orestova Vasilisa R. , Maslennikova Irina A. ,   Russian State University for the Humanities
Published: April 2023

The article presents a study of the personal characteristics of middle-aged people who have changed their profession. The study involved 100 people (n=100), who made up two groups – respondents who changed their profession during their lifetime, and people who work all their lives in one profession. The results obtained indicate that respondents who changed their profession have higher indicators than participants from the second group on a number of constructs: dispositional optimism, resilience, tolerance to uncertainty subjective well-being,. The article presents data on the respondents’ attitude to their childhood experience in terms of career prospects, as well as a correlation analysis between the respondents’ retrospective assessment of childhood experience and their current subjective life satisfaction, which revealed a direct relationship between those indicators. In addition, the professional trajectory of the study participants was comprehended in the context of the socio-economic development of our society for the last thirty years, a period when several economic (or political-economic) crises occurred that significantly affected the labor market. The results of the study indicate that the personal resources identified in the study are the most important factors contributing to the constructive passage of professional crises, professional development and success in the new conditions of a rapidly changing reality.
The first results of obtaining a hybrid hydrogel based on fibrin and polyvinyl alcohol: comparison with monocomponent hydrogels
Authors: Senokosova E. A. , Rezvova M. A. , Sevostyanova V. V. , Matveeva V. G.
Published: April 2023

Fibrin  displays  promising  characteristics  for tissue  engineering.  However,  it has suboptimal  physical  and mechanical properties when used as a material for cardiovascular applications. Obtaining an interpenetrating polymer network (IPN) hydrogel based on fibrin and polyvinyl alcohol (PVA) can improve the physical and mechanical characteristics and shrink behavior of fibrin.

Aim: To perform sequential polymerization of fibrin and PVA to obtain IPN hydrogel and analyze its properties in comparison with monocomponent hydrogels.

Material and Methods. Fibrinogen was isolated from the peripheral blood of patients using ethanol precipitation, then polyvinyl alcohol dissolved in saline was added to it. First, fibrin polymerization was initiated by adding calcium chloride to the solution. Then, it was followed by polyvinyl alcohol undergoing freeze–thaw cycles. Thus, a hydrogel based on fibrin and PVA, samples from pure fibrin and pure polyvinyl alcohol were prepared. We studied the structure of hydrogels, their physical and mechanical properties, shrink behavior and biological activity. Statistical data processing was carried out using the GraphPad Prism 6 software.

Results. 3D structure of the hydrogel is presented by polyvinyl alcohol polygonal cavities with a network of thin fibrin fibers. The distribution of components was equal in the inside of the samples, while polyvinyl alcohol prevails on the surface. Elongation (247 (220.0; 293.2)%; p = 0.0005) and Young’s modulus (0.09 (0.11; 0.13) mPa; p = 0.0001) of the hydrogel were statistically significantly higher compared to fibrin values. The hydrogel did not shrink, unlike fibrin that shrunk (11-fold decrease in volume). The number of adherent endothelial cells on the hydrogel matrices was 8 times higher than on polyvinyl alcohol, but 10 times lower than on fibrin. There was no proliferative activity of cells on polyvinyl alcohol, but 13.6% of proliferating cells were noted on the IPN hydrogel, and 59.52% on fibrin

Conclusion. Using sequential polymerization to obtain the IPN hydrogel based on fibrin and polyvinyl alcohol provides an equal distribution of fibers in the thickness of the material, making it possible to obtain hydrogels with improved mechanical properties and shrink behavior. However, the components on the surface of the IPN hydrogel need to be redistributed - more polyvinyl alcohol should be added still maintaining a relatively low adhesiveness of the material. Therefore further research is necessary to create the most optimal conditions for cell activity.
Evaluation of the antimicrobial activity of a pyrimidine compound 2-methyl-3-(2-phenyl-2-oxoethyl) quinazolin-4(3H)-on against Klebsiella pneumoniae under in vivo conditions
Authors: Tsybizova A. A. , Yasenyavskaya A. L. , Tyurenkov I. N. , Ozerov A. A. , Samotrueva M. A.
Published: April 2023

The greatest danger is the development of multiple antimicrobial resistance in microorganisms, including Klebsiella pneumoniae, which actualizes the necessity of development and synthesis of new antimicrobial compounds. Considering the versatile pharmacological activity, pyrimidine compounds became a subject of interest for scientists in the aspect of their use as a basis for new antimicrobial agents.

Aim: To assess the antimicrobial activity of the pyrimidine compound 2-Methyl-3-(2-phenyl-2-oxoethyl)quinazoline-4(3H)-on against Kl. pneumoniae under in vivo conditions.

Material and Methods. The antimicrobial activity in vivo of the compound 2-Methyl-3-(2-phenyl-2-oxoethyl)quinazolin-4(3H)-on against Kl. pneumoniae was performed simulating generalized infection by intraperitoneal injection of the pathogen at a dose of 3 × 106. The experiment was conducted on CBA line mice (40 animals) divided into groups: control I – animals received intraperitoneal injection water; control II – infected animals received no treatment; experimental groups – mice with generalized infection treated with ceftriaxone at the dose 50 mg/kg intraperitoneally for 7 days, and the animals receiving the test compound at the dose 27 mg/kg against infection in the same mode. Antimicrobial activity was assessed by the following parameters: animal survival rate; internal organ and blood infestation index; total leukocyte count, C-reactive protein and procalcitonin.

Results. It was found that pyrimidine derivative 2-Methyl-3-(2-phenyl-2-oxoethyl)quinazoline-4(3H)-on has a marked antimicrobial activity against Kl. pneumonia appeared in increase of animal survival in the conditions of generalized Klebsiella infection as well as in decrease of total leukocyte count, C-reactive protein and procalcitonin levels that confirms the reduction of the inflammatory reaction.

Conclusion. Thus, the pyrimidine derivative 2-Methyl-3-(2-phenyl-2-oxoethyl)quinazoline-4(3H)-on exhibits antimicrobial activity, comparable with ceftriaxone, against Klebsiella pneumoniae in experimental generalized Klebsiella infection.
Satisfaction with the quality of outpatient care of medical students as an element of the assessment of the current system of medical care
Authors: Chukreyev M. P. , Kalinkin D. E.
Published: April 2023

Introduction. This article discusses the problems of the quality of outpatient care for medical students. Most of the students prefer not to seek medical help from specialists even in difficult situations, and in most cases they self-medicate. This is caused by an insufficient degree of quality service by the outpatient polyclinic service of the attached contingent. The existing state system of medical care is imperfect: there is no unified approach to the organization of student polyclinics; medical organizations do not take into account the age and social specifics of students; low continuity in the rehabilitation and treatment of patients; there is insufficient preventive work among students.

Aim: To determine the level of satisfaction with the quality of medical services provided to medical students.

Material and Methods. The sociological method included a survey of medical students (1026 respondents) according to a specially designed questionnaire that contained questions about the scope, nature, quality of work and satisfaction with the conditions of the polyclinic institution. The logistic method consisted in the analysis of personnel, resource provision, as well as the activities of the medical institution.

Results. Most of the medical students encounter organizational obstacles (appointment, waiting lists at the registry, waiting lists at the day hospital, waiting lists at the reception, etc.). 38.0% of respondents noted that when health problems appear, it is easier for them to go to the medical office of the college than to the district doctor. Moreover, 64.3% of respondents do not have information about the district doctor. Satisfaction depends on a number of factors such as: waiting time for a doctor’s appointment at the office (p < 0.001), availability when making an appointment with a doctor at a polyclinic (p < 0.001), preference when contacting a doctor when health problems appear (p < 0.001), the presence of organizational difficulties to get an appointment or treatment in a polyclinic (p < 0.001), the location of the registry and specialist offices, the terminal for making an appointment (p < 0.001), as well as the conditions of stay in a medical facility (p < 0.001).

Conclusion. The necessity of introducing feedback into the practice of working with a contingent of medical students, using available screening technologies to actively identify the most significant factors and risk groups of the most common pathology, taking measures to reduce the impact of controlled factors, as well as annual preventive examinations and medical examinations has been identified.
Correlation of epicardial adipocytes hypertrophy with adipokines, inflammation and glucose and lipid metabolism
Authors: Koshelskaya O. A. , Naryzhnaya N. N. , Kologrivova I. V. , Suslova T. E. , Kravchenko E. S. , Charitonova O. A. , Andreev S. L. , Margolis N. Yu. , Sharipova N. G. , Krapivina A. S.
Published: April 2023

The changes of epicardial adipose tissue’s (EAT) morphofunctional characteristics represent an important factor of cardiometabolic impairments development. However, factor data determining the severity of EAT adipocytes’ hypertrophy in patients with coronary atherosclerosis are absent in literature.

Aim: To compare the size of the EAT adipocyte and the percentage of hypertrophied adipocytes with the parameters of glucose/insulin metabolism, blood lipid transport function, adipokines’ profile and serum levels of high sensitive C-reactive protein (hsCRP) in patients with chronic coronary artery disease (CAD) undergoing coronary artery bypass grafting (CABG); to establish statistically significant determinants of a pronou ced degree of EAT adipocytes’ hypertrophy.

Material and Methods. The study included 42 patients (m/f 28/14) aged 53–72 y.o. with CAD, who underwent CABG. The material for the study was EAT adipocytes obtained by the enzymatic method from intraoperative explants. The basal blood levels of glycemia, insulinemia, C-peptide, blood lipid transport function, adipokines and hsCRP were determined. The median indicators of the size of EAT adipocytes and the proportion of EAT adipocytes over 100 μm were 87.32 μm and 14.64%, respectively. The total sample of patients was divided into two groups: gr. 1 with an average size of EAT adipocytes less than or equal to 87.32 μm and gr. 2 with an average size of EAT adipocytes more than 87.32 μm. Gr. 2 had higher body mass index, waist and hip circumferences, triglycerides, hsCRP, and lower adiponectin levels, while the median proportion of hypertrophied adipocytes was three times higher than in group 1. A model of multiple logistic regression was constructed, according to which statistically significant determinants of the pronounced EAT adipocytes’ hypertrophy are represented by the decreased level of adiponectin, and increased concentrations of hsCRP and C-peptide, which reflects the biosynthesis and secretion of insulin. The predictive accuracy of the model was 82%, sensitivity 85%, specificity 79%, AUC = 0.89.

Conclusion. Our results indicate a close correlation between the development of EAT adipocytes hypertrophy, impaired production of adiponectin, insulin, and inflammation processes. Concentrations of adiponectin, hsCRP, and basal C-peptide in the blood are biomarkers that accurately determine the presence of EAT adipocyte hypertrophy.
Changes in oscillatory and nonlinear dynamic processes of microcirculation in patients with obliterating atherosclerosis of lower limb arteries after revascularization
Authors: Vasiliev A. P. , Streltsova N. N.
Published: April 2023

Aim: To study the nature of changes in oscillatory and nonlinear dynamic processes in the skin microcirculatory system by laser Doppler flowmetry in patients with obliterating atherosclerosis of the lower limbs arteries (OALLA) after limb revascularization.

Material and Methods. 27 male patients with OALLA before and after endovascular revascularization of the affected limb (median age 63.0 [60.0; 69.0] years) were studied. Microcirculation (MC) of the foot skin with assessment of nonlinear dynamic processes and spectral wavelet analysis of blood flow fluctuations was studied by laser Doppler flowmetry. The normalized amplitude indices of blood flow fluctuations were determined in frequency ranges reflecting: endothelial, neurogenic, myogenic, respiratory, pulse factors of hemocirculation. Bypass parameters and nutritive blood flow were assessed. An occlusion test was performed to determine capillary blood flow reserve. The study of nonlinear dynamic processes included assessment of fractal dimension, entropy determination and phase portrait analysis.

Results. Limb revascularization in patients with OALLA resulted in improvement of the clinical picture accompanied by statistically significant increase in nutritive blood flow (+9.7%) and reserved dilatation potential of microvessels (+43.2%), decrease in arteriolo-venular blood shunting (–5.0%) and venous plethora (–14.3%). The analysis of nonlinear dynamic processes of the MC showed that after angioplasty, along with the remaining deficit of oscillatory processes energy, there was a decrease in the fractal dimension index (–14.3%), indicating the limitation of lability of the functional system of the microvascular bed. At the same time, an increase in the chaotization of the regulatory mechanisms of the peripheral blood flow was established.

Conclusions. The results showed positive functional changes of the MC system associated with the improved clinical picture in patients with OALLA after limb revascularization. At the same time, changes in the nonlinear dynamics parameters indicate a compensatory increase in the chaotization of the system together with the remaining limitation of its functional lability and the energy deficit of oscillatory processes.
Morphological features of epithelial-mesenchymal transformation and its effect on tumor progression of breast cancer
Authors: Kondratyuk R. B. , Grekov I. S. , Shvorob D. S. , Seleznev E. A.
Published: April 2023

Introduction. Breast cancer is in the first place in the structure of morbidity among all malignant neoplasms in women. The prognosis of the disease depends on the tumor degree, including the presence of epithelial-mesenchymal transformation (EMT), the degree of invasion, the proliferative index, the preservation or absence of estrogen, progesterone, and epidermal growth factor receptors.

Aim: To study the immunohistochemical and morphological characteristics of the epithelial-mesenchymal transformation of breast cancer.

Material and Methods. Immunohistochemical study with antibodies to AE1/AE3, HMW, CK18, Snail, HER2/neu, E-cadherin, Vimentin, α-SMA, CD34, Ki-67 and p63 was performed in 60 patients of different age with breast cancer. Native preparations were stained with picrofuchsin according to van Gieson Alcian blue. Inflammatory infiltrate cells were examined for antibodies CD45, CD3, CD4, CD8, CD20, CD68.

Results. In ductal carcinoma, positive expression for estrogen and progesterone was found in 82.7% and 86.3%, respectively, the proliferation index ranged before 66,6%, and p-53 was positive in 97%. In lobular cancer, positive expression to estrogen and progesterone was observed in 83.4% and 66.6%, respectively, the index of proliferative activity at the level of 50%, and p-53 was positive in 66.6%. Positive moderate expression of HER-2/neu was determined in 47% of ductal and 50% of lobular cancers. Estrogen plays an important role in the development of invasive breast cancer, leads to tumor progression and contributes to EMT. EMT, in turn, leads to the expression of E-cadherin associated with a worse survival prognosis. EMT indirectly leads to the intensification of angiogenesis, and the presence of a large number of newly formed vessels increases the risk of metastasis. Histochemical methods were used to determine the growth of fibrous tissue around invasively growing cancer complexes. Cells located perifocally looked like fibrobla ts, immunohistochemically moderately expressed Vimentin and weakly expressed pancytokeratin, which proved the tumor nature of the cells and the acquisition of mesenchymal features by them. The inflammatory infiltrate along the periphery of the tumor growth consisted mainly of T- and B-lymphocytes, and around the cancer complexes - of B-lymphocytes and macrophages.

Conclusion.  The  study  of  the  immunohistochemical  tumor  phenotype  will  make  it  possible  to  prescribe  adequate polychemotherapy and determine the prognosis of the course of the disease.
Serbest Muhasebeci Mali Müşavirlere Yönelik İş İlanlarında Aranan Şartların Karşılaştırmalı Analizi: Türkiye, Amerika Birleşik Devletleri ve İngiltere Örneği
Authors: KAYA Ahmet
Published: April 2023

Kalifiye insanların işletmeler tarafından seçimi oldukça zor ve maliyetli bir süreçtir. Teknolojik gelişmeler ve dijitalleşme sayesinde işletmeler günümüzde, arzu ettikleri özelliklere ve yetkinliklere sahip bireylere ulaşabilmek ve onları işe almak adına çeşitli internet ortamlarında iş ilanları vermektedirler. İş ilanlarında çoğunlukla aday iş görenlerde aranan temel özellikler ve yetkinlikler; maaş, tecrübe durumu, eğitim durumu, askerlik durumu, mezun olunan bölüm, ikamet yeri, sunulacak sosyal imkânlar ve buna benzer bilgiler yer almaktadır. Elektronik ortamlardaki bu ilanlar sayesinde işletmeler daha kısa sürede daha fazla adaya ulaşmakta iken adaylar da aynı anda birden fazla ilana ilişkin bilgi sahibi olmaktalardır. Bu çalışmada, Türkiye, ABD ve İngiltere’de Serbest Muhasebeci Mali Müşavirlere yönelik olarak verilen iş ilanlarını incelemek ve adaylarda aranan temel becerileri belirlemek amaçlanmıştır. Bu doğrultuda, kariyer.net ve indeed.com internet sitelerinde yer alan iş ilanları toplanmıştır. Her bir ülke için 100 iş ilanı içerik analizi yöntemiyle incelenmiştir. Sonuç olarak, bilgi teknolojilerini kullanma ve rapor yazma becerilerinin, üç ülkede de verilen ilanlarda en fazla talep edilen nitelik bakımından ilk üçte yer aldığı tespit edilmiştir. Ayrıca Türkiye’de verilen iş ilanlarında rutin becerilerin ön plana çıktığı, çevreyle uyum becerilerinin ise neredeyse hiç talep edilmediği bulgulanmıştır. ABD’de verilen iş ilanlarında kişisel beceriler dışında kalan diğer becerilerin önem düzeylerinin neredeyse homojen bir şekilde olduğu görülmüştür. Kişisel becerilerin ise neredeyse hiç şart koşulmadığı anlaşılmıştır. İngiltere’de verilen iş ilanlarında ise beş beceri grubundan hemen hemen eşit sayıda becerinin ön plana çıktığı tespit edilmiştir.
النظائر المخادعة الجزئية بين اللغتين العربية والتركية
Authors: الحسن محمد موفق
Published: April 2023

تُمثِّل النظائر المخادعة الجزئية، أو أزواج الكلمات التي تتشابه كتابيًا أو صوتيًا بين لغتين لكنها تختلف في بعض معانيها بين اللغتين، قسمًا من ظاهرة النظائر المخادعة التي تشكّل صعوبة في الدراسات البين لغويّة؛ مثل تعلم اللغات الأجنبية وتعليمها، والترجمة. ورغم أنّ دراسة النظائر المخادعة قد حظيت بدراسات مستفيضة في اللغات الأجنبية؛ إلّا أنها ما تزال شحيحة فيما يخص اللغة العربية، وهذا ما دفعنا لاختيار دراسة النظائر المخادعة بين العربية والتركية؛ لكثرة الكلمات العربية المقترضة في اللغة التركية من جهة، ولتزايد الاهتمام بتعليم اللغتين في الفترة الأخيرة. وقد حصر البحث أزواج الكلمات تلك، ثم حاول تحديد التغيرات الدلالية التي شهدتها الكلمات العربية المقترضة في اللغة التركية وأدت إلى تمايز دلالاتها جزئيًا مع دلالاتها الأصلية المستعملة في اللغة العربية. وقد خَلُص البحث إلى جملة من النتائج؛ منها: أن هناك عددًا لا بأس به من النظائر المخادعة الجزئية في اللغتين العربية والتركية. أيضًا احتفظت هذه الكلمات في اللغة التركية بمعنى أصلي واحد على الأقل من معانيها المستخدمة في اللغة العربية، لكنها طوّرت في اللغة التركية معنىً، أو معانيَ إضافية مختلفة غير مستخدمة في دلالات الكلمة الأصلية في اللغة العربية. كما سلكت هذه الكلمات في تطويرها للمعاني الجديدة طرقًا عديدة من التغير الدلالي كتعميم الدلالة، وتخصيص الدلالة، والنقل الدلالي. ويُنتظَر من هذا البحث أن يسدّ فراغًا في حقل الدراسات البين لغوية، وفي حقل التحليل التقابلي للغة العربية، وأن يساهم في تسهيل مهمة وضع مناهج تعليم اللغة العربية للأتراك، ومناهج تعليم اللغة التركية للعرب. وسيشكل هذا البحث مُنطلَقًا وأساسًا لبحوث أخرى توسع دائرة البحث في التحليل التقابلي للغتين العربية والتركية على مستويات اللغة كافة.
كرونولوجية الاستعارة: من البلاغة القديمة إلى البلاغة التأويلية
Authors: العنكري خالد
Published: April 2023

نسعى من خلال هذه الورقة البحثية إلى تتبع مفهوم الاستعارة في المنُجَز البلاغي العربي القديم، وفي اتجاه جديد من الاتجاهات البلاغية المعاصرة الموسوم بـ: "البلاغة التأويلية"، الذي جعل من الاستعارة آلية لتحليل الخطاب، مع الكشف عن التغييرات التي طرأت على المفهوم، وبيان منظور الاشتغال التحليلي التأويلي في ضوء النظرية البلاغية التأويلية؛ لتصير الاستعارة وفق هذا الاتجاه التجديدي أداةً قادرةً على تفكيك الخطاب وتأويله؛ بهدف تحصيل المعنى، وبناء دلالاتٍ جديدة، من خلال الانفتاح على ما جاد به التراث العربي، والمناهج النقدية الغربية، والجهود اللسانية، وهو ما أسهم في إحداث آليةٍ إجرائيةٍ جديدةٍ وسمت بـ"الاستعارة المنوالية"، التي تضمّنت حمولة معنوية جديدة، كما أظهرت كيفية تحليلية وتأويلية مغايِرة لما جاءت به الجهود البلاغية والنقدية واللسانية السابقة، التي استفادت منها في التنظير والأجرأة.
YouTube for second language learning: What does the research tell us?
Authors: Dizon Gilbert
Published: April 2023

Since its inception in 2005, YouTube has grown to become one of the most trafficked online platforms in the world. Accordingly, second language (L2) research interest on the topic has also increased, with studies investigating its use in formal and informal settings. Given this, the goal of this conceptual paper is to identify patterns within L2 research concerning YouTube in order to develop a better understanding of the benefits and limitations of the video streaming service for language learning purposes. This conceptual article is divided into four primary sections. First, the author justifies the use of YouTube for L2 learning using two theoretical frameworks. Secondly, studies pertaining to YouTube in formal and informal L2 environments are reviewed. The reviewed studies are then analyzed in order to highlight relevant benefits and limitations of the platform for L2 learning. To conclude, L2 research and pedagogical implications are discussed.
Review of Pronunciation Instruction in English for Academic Purposes: An Investigation of Attitudes, Beliefs and Practices
Authors: Ranjbaran Fatemeh
Published: April 2023

Pronunciation Instruction in English for Academic Purposes: An Investigation of Attitudes, Beliefs and Practices by John Hodgetts, 2020, 267pp., $169.99 (Paperback). ISBN 9783030561185
Should standard Arabic have "the lion's share?": Teacher ideologies in L2 Arabic through the lens of pedagogical translanguaging
Authors: Azaz Mahmoud , Abourehab Yousra
Published: April 2023

With the multilingual turn in applied linguistics, translanguaging has been envisioned as a pedagogical approach in multiple contexts (Creese & Blackledge, 2010; Galante, 2020; Yilmaz, 2019). Recent discussions have turned to teachers’ perspectives to understand how teachers’ monolingual ideologies and beliefs could limit the potential of such approaches (Hillman et al., 2019; Holdway & Hitchcock, 2018; Tian, 2020). With a focus on Arabic as a multidialectal and multiglossic language, this paper examines teachers’ translanguaging ideologies and practices and their nexus to language learning and intercultural communication. It used a focused, semi-structured interview to determine to what degree teachers’ practices were consistent or in conflict with their ideologies regarding translanguaging. They were challenged with positions from translanguaging pedagogy to initiate their conceptual development. A discrepancy was found between teachers’ ideologies and practices. That is, whereas they initially hesitated to accept translanguaging as a legitimate pedagogy, they were indeed translanguaging. This discrepancy is argued to limit learning. A qualitative analysis of the interviews with some teachers showed the emergence of an internally persuasive discourse about the potential of translanguaging. In light of teacher reflections that specified legitimate challenges, we argue for the judicious adoption of translanguaging pedagogy in multilingual and multicultural settings and discuss pedagogical implications and future research directions.
Identification norm in the digitalization of interstate supply chains context
Authors: Feshchenko S.
Published: April 2023

The results of a study of the concept of «identification» in the regulatory legal documents of the Eurasian Economic Union, the Republic of Belarus and the Russian Federation as an important component of the digitalization of the interstate supply chain are presented. Disagreements in the interpretation of this term are revealed and an approach to avoid them is proposed.
President Reagan’s Situational Leadership: Focusing on the strategy of the collapse of the Soviet Union
Authors:   Institute of East and West Studies Yonsei University, Lee Ho , Lee Hyun-Chool
Published: April 2023

This paper analyzes the leadership of President Reagan, who is credited with winning the Cold War and restoring American pride, by focusing on his strategy for the collapse of the Soviet Union. Reagan pursued ‘peace through strength’ and implemented strategies to fulfill this vision, arguing that the existing policies of containment and détente were ineffective and deceptive. First, he cut off the flow of funds to the Soviet Union by blocking the flow of technology to the Soviet Union, sabotage operations through the supply of fake technology, and a strategy to depress international oil prices. Second, the Soviet-Afghan war and the development of the SDI were used as a “poison pill” to make the Soviets pour money into the country like water. Third, he supported democratization in Poland and Eastern Europe, and used human rights as a weapon in the public opinion war to pressure the Soviet Union into regime change. Finally, his leadership was marked by his ability to persuade the public as a great communicator. To be effective, a political leader must have a guiding ideology that is responsive to the times and historical calling. He was a leader who was able to adapt his approach to the changing political environment and demonstrated situational leadership, using both transactional and transformational leadership to achieve his goals. In other words, he had a sense of the times and was able to articulate a vision to the people. In this respect, President Reagan is a prime example of the importance of situational leadership.
IMPORTÂNCIA DO ALEITAMENTO MATERNO NO DESENVOLVIMENTO DO SISTEMA ESTOMATOGNÁTICO
Authors: SILVA Alanna Moreira da , SCATOLIN Renata Siqueira , OLIVEIRA Ana Luísa Botta Martins de
Published: April 2023

O aleitamento materno está relacionado com o
desenvolvimento satisfatório do sistema estomatognático. Durante o ato de amamentação, a criança realiza uma intensa atividade muscular para que consiga executar o movimento de sucção do leite, estimulando toda a musculatura da face. Além disso, o selamento labial ao fazer a sucção, faz com que a criança respire pelo nariz estimulando o desenvolvimento da respiração nasal. Este processo é distinto quando a criança é submetida a uma amamentação artificial. O objetivo do presente estudo foi realizar uma revisão de literatura, por meio de pesquisa nos bancos de dados SCIELO, BVS, de artigos recentes dos últimos 11 anos, pontuando a importância que o aleitamento materno exerce no desenvolvimento estomatognático da criança. Por meio desta revisão de literatura observou-se que, tanto o tipo de aleitamento (artificial ou natural) quanto o tempo do mesmo, tem forte impactos no desenvolvimento do sistema estomatognático, seja na fala, deglutição, mastigação ou respiração da criança. A importância do aleitamento materno deve ser salientada, para que esse ato dure pelo menos
os seis primeiros meses de vida da criança minimizando assim as chances de a criança desenvolver hábitos deletérios.

Palavras-chave: Aleitamento materno. Odontopediatria. Sistema estomatognático.
DIVERSIDADE FLORÍSTICA E TRANSMISSÃO CULTURAL DO CONHECIMENTO ETNOBOTÂNICO EM QUINTAIS DE COMUNIDADES RURAIS NO MUNICÍPIO DE JANAÚBA, MINAS GERAIS, BRASIL
Authors: SILVA Wesley Alves , Santos Carlos Alberto Batista , ANDRADE Wbaneide Martins de
Published: April 2023

Objetivo: Descrever e analisar o conhecimento tradicional local de moradores que residem em três comunidades rurais no município de Janaúba, Minas Gerais no que se refere aos usos de plantas cultivadas em quintais, além de identificar e registrar a diversidade florística nesses ambientes. Material e métodos: Foram realizadas entrevistas semiestruturadas, turnês guiadas e grupo focal junto aos informantes-chave, selecionados através da técnica bola de neve. Para investigar a relação entre variáveis socioeconômicas (idade, gênero, escolaridade e renda) e o uso e conhecimento de plantas foram utilizados Modelos Lineares Generalizados. Foi calculado o Valor de Uso (VU) das espécies botânicas citados pelos entrevistados e também o índice de diversidade de Shannon-
Wiener. Resultados e discussão: Registrou-se 155 espécies pertencentes a 62 famílias botânicas, destacando-se as famílias Asteraceae, Fabaceae e Lamiaceae. O conhecimento etnobotânico sobre a riqueza de espécies e as variáveis socioeconômicas teve uma relação positiva estatisticamente com a comunidade, sexo e escolaridade. As espécies foram categorizadas em 7 tipos de uso, sendo as mais importantes alimentares e medicinais. Dentre as espécies com maior Valor de Uso para os entrevistados, destacaram-se acerola, goiaba, manga, pinha e laranja. Os índices de Shannon-Wiener indicaram uma diversidade alta nos quintais das comunidades estudadas. Conclusão: Os quintais em Janaúba/MG são
de grande importância como campo de socialização rural, palco de cultivo de tradições culturais, produção de conhecimento popular da biodiversidade.

PALAVRAS-CHAVE: Conhecimento tradicional. Agrobiodiversidade. Componentes estruturais. Semiárido Mineiro
ADMISSIBILIDADE DO RECURSO ESPECIAL, PEC DA RELEVÂNCIA 39/21 E SUAS PARTICULARIDADES
Authors: SILVA Allysson Cristiano Rodrigues da
Published: April 2023

Este artigo traz uma reflexão acerca da emenda constitucional 39/21, apelidada de PEC da Relevância. Essa PEC cria mais um requisito de admissibilidade do recurso especial, sendo sempre analisadas sobre as ações penais, ações de improbidade administrativa, ações de causas superiores a 500 salários mínimos, ações sobre inegibilidades, recursos sobre decisões que contrariam jurisprudência dominante do STJ e outras hipóteses definidas em lei, ou seja, a exigência de demonstração da relevância da questão jurídica de direito federal. Isso significa dizer que é preciso demonstrar em cada um dos recursos que subam aos tribunais de superposição que elas se objetivam. Objetivo: O objetivo do presente artigo é analisar, em termos gerais, as motivações que levaram à promulgação da Emenda Constitucional 39/21, as novidades efetivamente implementadas ao juízo de admissibilidade do recurso especial e, a partir disso, refletir sobre os possíveis impactos que as novas regras trarão na condução dos processos judiciais doravante. Metodologia: Este estudo tratou-se de uma revisão bibliográfica de natureza descritiva e exploratória acerca da PEC
39/21elaborada através de levantamento bibliográfico em artigos científicos indexados em sítios bases de dados do Scientific Eletronic Library Online (SCIELO) e do Google Academic, valendo-se para tanto de doutrinas,legislações, paper e artigos correlatos, artigos científicos indexados em sítios bases de dados do Scientific Eletronic Library Online (SCIELO) e do Google Academic. Os critérios de inclusão dos referenciais do texto foram artigos científicos disponíveis em língua portuguesa, referentes PEC da Relevância, no ordenamento jurídico brasileiro. Conclusão: A PEC da Relevância 39/21 é admissível como recurso especial, desde que preenchidos os requisitos
formais de admissibilidade e que seja demonstrada a existência de um direito líquido e certo em debate. Além disso, para a admissão da PEC, o Juiz deverá atentar para a relevância da matéria em questão, o interesse público, a utilidade social e a adequação da PEC ao ordenamento jurídico.

Palavras-chave: PEC da Relevância. Emenda constitucional. Ordenamento jurídico. Recurso especial