bluuebunny/crossref_metadata_2025 huggingface dataset:
Analgesic, anti inflammatory and toxicological effects of Vigornatural herbal powder in experimental animals
Authors: Ozioko Fabian U , Inuaeyen Jacob U , Emmanuel Stephanie O , Ugwu Ezinne B , Ugonabo Onyinyechukwu Y , Amoke Chisom M , Ikechukwu Peter E , Eze Fabian I
Published: January 2024

Purpose: To determine the analgesic, anti-inflammatory and toxicological effects of Vigornatural herbal powder, derived from the leaves of Nicotiana tabacum L. (Solanaceae) and the seeds of Buchholzia coriacea Eng. (Capparaceae).

Methods: Analgesic and anti-inflammatory effects of the herbal powder were assessed using acetic acid-induced writhing and egg-albumin-induced edema models, respectively. Drugs were administered orally to animal groups (n = 4) at a dose of 400 mg/kg using paracetamol and Tween-80 as positive and negative controls, respectively in writhing test, while in egg albumin model, drugs were administered at a dose range of 100 - 400 mg/kg using diclofenac sodium and Tween 80 as controls respectively. Acute toxicity was evaluated using modified Lorke’s protocol. Sub-acute toxicity was investigated in Wistar rats after 14 days of oral administration of 400 mg/kg per day via its effect on hematological and serum biochemical parameters. Qualitative phytochemical analysis was carried out using standard protocols.

Results: The herbal powder gave a median lethal dose (LD50) > 5000 mg/kg and significantly provoked 38 % inhibition of acetic acid-induced writhing in mice at 400 mg/kg dose, relative to negative control (p < 0.05). It also significantly inhibited both phases of egg-albumin-induced edema with 9.5 and 16.5 % inhibition at 1st and 4th hours, respectively when compared to standard diclofenac which gave 4.2 and 17.3 %, respectively (p < 0.05). There was no significant difference between the treated and control groups with regard to all hematological and biochemical parameters tested after 14 days. Qualitative phytochemical tests showed the presence of alkaloids.

Conclusion: Vigornatural herbal powder possesses fairly good analgesic and anti-inflammatory properties and does not have any significant adverse effect on hematological, hepatic and renal functions. Further studies to develop it as a potential novel analgesic and anti-inflammatory pharmacotherapeutic agent is recommended.
Anti inflammatory and human chondrocyte protective effect of Drynariae rhizoma extract
Authors: Lee Sung-Gyu , Kang Hyun
Published: January 2024

Purpose: To evaluate the anti-inflammatory properties of Drynariae rhizome (Polypodiaceae) extract (DRE) on lipopolysaccharide RAW264.7 macrophage cells and its protective effects on interleukin (IL)-1β-stimulated SW1353 chondrocyte cells.

Methods: The anti-inflammatory effect of DRE (12.5, 25, 50, and 100 µg/mL) were measured by 5-lipooxygenase (LO) and cyclooxygenase (COX)-2 enzyme inhibitory activities, nitric oxide (NO) production in LPS-stimulated RAW264.7 cells using Griess reagent assay. Prostaglandins (PGE2) and leukotriene (LTB4) production were measured using enzyme-linked immunosorbent assay (ELISA). To investigate the protective effect on chondrocytes, the level of matrix metalloproteinases (MMP)-3, -9, and tissue inhibitor of matrix metalloproteinase (TIMP)-1 was determined using zymography assay and ELISA kit in SW1353 cells stimulated with IL-1β.

Results: Drynariae rhizome (Polypodiaceae) extract (DRE) had a significant (p < 0.05) inhibitory effect on 5-LO and COX-2 enzymes in a concentration-dependent manner compared to untreated group. In RAW264.7 cells, levels of NO, PGE2 and LTB4 of DRE group were significantly (p < 0.05) decreased in study group (treated with DRE) at 12.5 μg/mL compared to the group treated with LPS (100 ng/mL) alone. Additionally, in SW1353 human chondrocytes stimulated with IL-1β, MMP-3 and MMP-9 were significantly (p < 0.05) suppressed in DRE-treated group compared to IL-1β group alone, with no significant impact on TIMP-1 production.

Conclusion: Drynariae rhizome (Polypodiaceae) extract (DRE) possesses anti-inflammatory and cartilage protection effects. It therefore has the potential to be developed as an effective natural pharmaceutical agent for inflammation or osteoarthritis.
Increasing Psychological Well-Being Through Role Awareness Training Among Student-Athletes in National Potential Young Athlete Training Center
Authors: Jannah Miftakhul , Khoirunnisa Riza Noviana , Satiningsih Satiningsih , Jaro'ah Siti , Widohardhono Rachman , Putri Andi Ledy Permata , Rachman Nabila , Sauda Muhammad Aufa Al Farisi Ann Haba
Published: January 2024

Objective: In response to the problem of the dual career of student-athletes during quarantine resulting in a psychological well-being crisis. This study aims to assess the effect of role awareness training developed to improve the psychological well-being of student-athletes. The study aims to determine the effect of role awareness training on psychological well-being in student-athletes at the National Potential Young Athlete Training Center. Method: A quantitative experimental method with a pretest-posttest control group design was used. The subjects of this research were 24 athletes of the National Young Athlete Training Center. Sampling is done with a saturated sample, where all population members become a sample. Data was obtained through pretest and posttest using a psychological well-being instrument that contains 42 items. JASP (Jeffrey’s Amazing Statistics Program) for Windows software was used to analyze the data used in the study. The data analysis technique used was the independent sample t-test. Results:  The results showed that role awareness training can guide athletes in improving psychological well-being. Novelty: In response to the problem of the dual career of student-athletes during quarantine resulting in a psychological well-being crisis. This research concludes that role awareness training influences psychological well-being in student-athletes.
PENGELOLAAN SAMPAH DARI LINGKUNGAN TERKECIL DI KELURAHAN KASTURIAN KOTA TERNATE
Authors: Sahidun Nurfitri , Haryati Haryati
Published: January 2024

The focus of this community service activity is to make various kinds of creativity from managing plastic waste at home specifically for the community, especially the women of Kasturian Village in Ternate City, North Maluku. This community service activity was carried out for one day, on the 13 of February 2023. The results of initial observations on this service partner found that there was still a lot of plastic waste donated by residents of the Kasturian sub-district in every existing trash can. Therefore, the service team provides counseling and at the same time practices managing waste from the smallest environment by making various kinds of creativity. The results obtained after this service are increasing the enthusiasm of the community to manage plastic waste into various kinds of creativity.Keywords: Plastic waste; Smallest Environment
Evaluación del desempeño de un método comercial objetivo para la determinación del color de la yema en huevos de codornices (Coturnix coturnix japonica) recibiendo diferentes pigmentos en la dieta
Authors: Sánchez-Rodríguez Héctor L. , Muñiz-Colón Gladycia C.
Published: January 2024

Debido a que el uso del abanico de colores Roche (ACR; el estándar para determinación del color de la yema en huevos) puede ser subjetivo, se han desarrollado métodos alternativos capaces de tomar estas medidas en forma objetiva, incluyendo un analizador comercial de calidad del huevo (ACH; ORKA). Sin embargo, el ACH fue desarrollado para huevos de gallina, dejando indefinida su posible capacidad para analizar huevos de menor tamaño como los de codornices japonesas (Coturnix coturnix japonica). La presente investigación comparó ambos instrumentos en huevos de codorniz con diferentes tonalidades producidas mediante las siguientes dietas experimentales: dieta comercial (CONTROL; n=279), dieta comercial + pigmento amarillo (OroGlo; AMARILLO; n=133) o dieta comercial + pigmento rojo (Cantaxantina; ROJO; n=266). Ambos instrumentos tienen una escala del 1 al 15 (1=pálido y 15=intenso). Los datos se analizaron mediante los procedimientos GLIMMIX y CORR de SAS. El ACR detectó diferencias en color entre dietas con ROJO > CONTROL > AMARILLO (9.55±0.34, 6.80±0.09 y 5.88±0.12, respectivamente; P<0.0001). Un comportamiento similar se observó con el ACH con 7.43±0.23, 6.00±0.10 y 4.92±0.12 para ROJO, CONTROL y AMARILLO, respectivamente (P<0.0001). Los valores del ACR fueron 2.12 (ROJO), 0.80 (CONTROL) y 0.96 (AMARILLO) unidades mayores que los del ACH (P<0.0001). Se observaron coeficientes de correlación de 0.24 (P=0.0013), 0.48 (P<0.0001) y 0.74 (P<0.0001) entre ACH y ACR para CONTROL, AMARILLO y ROJO, respectivamente. La confiabilidad del ACH en huevos de codorniz, aunque moderada en huevos con altos valores de color, fue considerablemente baja en huevos con yemas pálidas.
IN VITRO EVALUATION OF A PERMETHRIN-BASED PESTICIDE FOR THE CONTROL OF HAEMATOBIA IRRITANS
Authors: Brau-Rodríguez Astrid R. , Curbelo-Rodríguez Jaime E. , Armstrong Arístides
Published: January 2024

IN VITRO EVALUATION OF A PERMETHRIN-BASED PESTICIDE FOR THE CONTROL OF HAEMATOBIA IRRITANS
Macroeconomía. Para comprender conceptos fundamentales
Authors: Montesdeoca Vásquez Silvia de los Ángeles , Gaibor Viteri Marlon Rodrigo , Garzón Puetate Wilfrido Alejandro
Published: January 2024

La Macroeconomía constituye un pilar esencial dentro del ámbito económico. A diferencia de la Microeconomía, que se ocupa de las decisiones individuales de consumidores y empresas, la Macroeconomía se encarga de analizar las variables económicas así pues podemos mencionar el crecimiento económico, el desempleo, la inflación y la política monetaria. Este libro ha sido diseñado como un recurso integral para ayudar a comprender los conceptos fundamentales de la Macroeconomía y desarrollar el pensamiento crítico con la finalidad de evaluar el funcionamiento de las economías a gran escala. A lo largo de esta guía, se abordará las metodologías y técnicas empleadas por economistas para analizar los comportamientos económicos, comprender las razones subyacentes de los fenómenos macroeconómicos y sugerir estrategias que puedan amplificar la prosperidad económica de la comunidad.
Micro y macroeconomía
Authors: Gaón Rojas Nancy Maricela , Ushiña Gualpa Juan Elias
Published: January 2024

El libro consta de cuatro unidades: “Introducción a la Microeconomía; oferta, demanda y equilibrio” “Elasticidad” “Teoría de la producción, utilidad, costos” “Costo de Oportunidad. Al final de cada unidad encontrará una autoevaluación que le permitirá medir el conocimiento adquirido. Estimado estudiante se le invita a revisar esta guía didáctica preparada para acompañar y orientar su autoaprendizaje; hay de igual manera, a realizar un análisis sistematizado y paralelo tanto del texto básico como de la guía didáctica, examinar la bibliografía complementaria, y utilizar los recursos físicos y virtuales puestos a su disposición.
Assessment of Potential Alkali-Carbonate Reactivity and Petrographic Analysis of Limestone from Samana Suk Formation Dhamtaur Area, District Abbottabad, Pakistan to Use as Aggregate
Authors: Ghaffar Abdul , Sattar Abdul
Published: January 2024

A detailed Limestone from the Samana Suk Formation in Dhamtaur, Pakistan, was studied to assess itspotential as a construction aggregate. The limestone contains variable amounts of dolomite, which can be harmful toconcrete. Petrographic analysis and ACR tests showed that the dolomite content is low and the limestone has low alkalireactivity. Engineering laboratory tests confirmed that the limestone meets ASTM and AASHTO standards foraggregate properties. Therefore, the limestone from Dhamtaur can be used as an aggregate in concrete and asphaltworks. The results of the engineering laboratory tests indicate that limestone from the Samana Suk Formation, locatedin the Dhamtaur area, exhibits specific gravity (2.84g/cm3), water absorption (0.0781%), Los Angeles abrasion value(20%), and sulfate soundness (2.23%). These findings strongly support the viability of utilizing these rocks asaggregate, aligning with the established standards of ASTM and AASHTO. A petrographic examination indicates thepresence of dolomite in a minor proportion (2-15%) with a Porphyrotopic-S type texture. Analysis of ACR resultsdemonstrates a slight expansion in the limestone (0-0.01%), implying low reactivity to alkali. Consequently, it isreasonable to propose the utilization of these rocks as a source of aggregate in concrete and asphalt projects.
LAW OF EVIDENCE – ULOGA RIMSKO-KANONSKOG POSTUPKA U RAZVITKU DOKAZNOG PRAVA
Authors:   Faculty of Law, University of Zenica, Bosnia and Herzegovina, Drino Dževad , Drino Škandro Maja ,   Municipal Court in Zenica, Bosnia and Herzegovina
Published: January 2024

In contemporary laws on criminal procedure in Bosnia and Herzegovina, as well as in the region, the penetration of elements of Anglo-Saxon law and the uncritical acceptance of the "fruit of the poisonous tree" rule in the matter of evidentiary law are visible. The look into the future is nevertheless based on the historical development of the final stage of judicial fact-finding, where it is noticeable that the inquisitorial procedure of post-classical Roman law was transferred to ecclesiastical, canon law, which greatly influenced the development of evidentiary law in continental law. Therefore, the question arises, what is the hierarchy of the value of evidence in the Roman procedure and in the later Middle Ages, when the church itself forbids priests from participating in the most widespread forms of the so-called. "God's judgments" or ordals (Lateran council from 1215). The paper analyzes the contrasts between the free evaluation of evidence and the system of legally binding or formal evaluation of evidence of the inquisition procedure, whereby the church tried to evaluate evidence for the conversion of sinners by developing the spirit of mercy, pity and compassion. Likewise, with St. Thomas Aquinas, sins bear the names of delicts of Roman law (furtum, seditio, homicidium...), while the inquisitorial process, as a judicially organized investigation, dominating the continental legal culture and jurisprudence until the middle of the 18th century, brings legal rules for the evaluation of evidence.
KRIVIČNA DELA PROTIV POLNE SLOBODE (MORALA) U SREDNjOVEKOVNOJ SRBIJI
Authors:   Faculty of Law, Megatrend University in Belgrade, Milović Marko
Published: January 2024

Provisions on crimes against sexual morality can be found in several Serbian legal sources, the most important of which are the Code of Saint Sava (Nomocanon) and Dušan's Code. In the Nomocanon, among other things, there were several provisions that protected sexual morality, especially when it came to incest, dishonor of a virgin, sodomy..., and these criminal acts that were considered a violation of the canon were under the jurisdiction of church authorities. The paper specifically reviews the provision on rape, i.e. kidnapping, which was provided for in Dušan's code and which was strictly punished, and for which it is characteristic that there was an important difference in terms of punishment, depending on the class affiliation of the perpetrator and the victim. That class difference in criminal law matters (if we can call it that!), but also in other areas of law, is nothing unusual and should be observed in the spirit of that time and, accordingly, the value system of that time. However, although the class social order of the time was protected, it was not an obstacle for this Code to be considered the most modern at that time. Also, a review was given to the second article of this Code, which punished the fornication (adultery) of a landlady, for which severe (corporal) punishments were also provided. We also pointed to several ruling charters (King Milutin, Stefan Dečanski, Dušanov) that were passed in the first half of the 14th century and in which rape is mentioned for the first time under the name of ``loom'' and ``girl's loom''. Unfortunately, there are no more detailed historical data on when and how the provisions from the aforementioned legal sources regarding sexual morality were applied
PRAVNA ZAŠTITA CRKVENE IMOVINE: PRAVNO-ISTORIJSKA ANALIZA, USTAV SRPSKE PRAVOSLAVNE CRKVE I ZAKON O CRKVAMA I VERSKIM ZAJEDNICAMA
Authors:   Institute for European Studies, Belgrade, Vasiljević Aleksandar
Published: January 2024

tate-ecclesiastical law as a discipline that regulates relations between the state and the church, with the example of the protection of church movable and immovable property, confirms the importance of agreement between secular and autonomous law. The legal and historical analysis of the state legal sources created in comparison with the church canons of the Ecumenical and Local Councils laid the foundations for the law protection of church property. Through examples of Serbian medieval legal sources, the author indicates that the attitude towards church property was inherited from Byzantium, accepted and passed on in modern times. Along with natural updating and revision, the legal protection of church property is regulated by modern state and church-legal sources in the Republic of Serbia. The relationship to church property in secular law is regulated today by the Law on Churches and Religious Communities, which is not only harmonized with the highest state act, but its fullness is realized through a complementary relationship with the highest legal act of autonomous law. Legal protection of church property is a model and direction for other examples in the field of state-ecclesiastical law.
Enhancing Customer Loyalty: Optimizing Barista and Store Atmosphere for Increased Customer Satisfaction
Authors: Alfiansyah Rifky , Pamungkas Rafly Abdi , Bakhri Saeful
Published: January 2024

The aim of this study was to investigate the impact of store atmosphere and baristas on customer loyalty, mediated by customer satisfaction as an intervening variable. The study was conducted with the hope of enhancing customer loyalty in coffee shops located in the city of Cirebon. Convenience sampling was employed in this study. The primary data was collected by distributing questionnaires to 115 consumers in coffee shops located in Cirebon city. The data was analysed using partial least squares (SEM-PLS) structural equation modelling with the Smart-PLS 3.0 application. The study's results indicate that the store's atmosphere has a positive impact on customer satisfaction and loyalty. Additionally, the barista variable was found to have a positive effect on customer satisfaction and loyalty. It was found that the customer satisfaction variable mediated the relationship between store atmosphere and baristas on customer loyalty. Achieving customer loyalty is not solely dependent on the store atmosphere and baristas. It is important to explore other variables that can contribute to this goal. Future researchers should investigate these variables further.
Batee Jirat-Batu Aceh Islamic Gravestones in Sultanate Banten Building New Historiography Aceh and Banten Relationship
Authors: Arifia Sariat , Mizuar Mizuar , Munawir Munawir , Ahyadi Yadi , Akmal Aslim
Published: January 2024

Othman Yatim's research has provided a clear picture of the influence of Acehnese stones, which are so abundant in the Malaysian peninsula, but on the other hand, there is still a need to carry out a more in-depth comparative study regarding the existence of similar tombstones in Indonesia, especially on the island of Java. On the island of Java itself, the Sultanate of Banten is the only kingdom whose sultans or kings have used Batee Jirat Batu Aceh typology tombstones for generations, from the beginning to the end of the Sultanate. Therefore, comparative research was carried out on similar tombstones in Aceh, and then an analysis of the reconstruction of past relations between Aceh and Banten, as the Big Spice City, which also played a major role in the spread of Islam in Indonesia, was carried out.
PRE-SERVICE STUDENT-TEACHERS’ PERCEPTIONS OF THEIR PROFESSIONAL IDENTITY THROUGHOUT COVID-19 PANDEMIC: A CASE STUDY IN GREECE
Authors: Fotopoulou Vasiliki
Published: January 2024

This paper seeks to investigate undergraduate students’ views regarding how the pandemic is perceived as having had an impact on them as future educators. The sample consists of students in pre-school education who experienced the pandemic and the changes it brought about during their undergraduate studies. The research data was collected through an anonymous questionnaire followed by a thematic content analysis. From the qualitative data analysis pertaining to the way in which the pandemic affected the respondents’ perception of themselves as a prospective teacher, four categories emerged: i. Changes and Transformations, ii. Loss/Absence, iii. Long Distance Technology, and iv. Experience. It becomes clear that respondents seem to perceive themselves as educators through coping with the changes they face, through utilizing new technologies, and through gaining experience or even lacking it. However, a notable finding of this research is the future perspective and further capitalizing on the experience the students went through. In some cases, this experience is seen as usable in similar circumstances in the future, while in others it is deemed as an all-purpose tool enabling them to overcome any kind of challenge. This research paper aims to contribute with its own approach to a more profound understanding of how the changes experienced by students in times of change and challenge are seen as something of value in reference to their identity.
 

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CURRENT SITUATION AND SOLUTIONS TO IMPROVE THE QUALITY OF TEACHING IN STEM EDUCATION IN GENERAL SCHOOLS: A CASE STUDY IN SOME NORTHERN PROVINCES OF VIETNAM
Authors: Hang Nga Nguyen Thi , Ngoc Muu Nguyen , Van Hung Ngo
Published: January 2024

The paper delves into the state and challenges of STEM (Science, Technology, Engineering, and Mathematics) education in schools. By conducting an intensive survey, it offers insights into the current status of STEM education and highlights the perceptions and difficulties faced by educators in adopting STEM methodologies. The study reveals that while there's an increasing recognition of the importance of STEM in the natural sciences curriculum, several obstacles impede its full implementation. A significant challenge is the difficulty in correlating real-world issues with natural science subjects, making it tough for educators to make lessons engaging and relevant. Furthermore, the lack of appropriate educational tools and materials, combined with inadequate infrastructural facilities in schools, further hampers the quality of teaching. Moreover, the research identifies a gap in the training of educators. Many teachers are unfamiliar with STEM, lacking both understanding and confidence in the approach. This is exacerbated by time constraints in the classroom and insufficient support from parents. Additionally, the paper points out that only a limited number of natural science topics can be aptly integrated into STEM projects, creating a narrower scope for educators. To address these challenges, the paper suggests the need for better training for teachers specifically tailored to STEM requirements, more substantial institutional support, and fostering a closer relationship between STEM education and the broader natural sciences curriculum.

 

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Relevansi Fungsi dan Tujuan Hukum Islam dalam Era Modern
Authors: Ridwan  , Kurniati  , Misbahuddin
Published: January 2024

AbstrakAgama, sebagai penuntun kehidupan dunia dan akhirat, memainkan peran sentral dalam Islam sebagai sistem hukum holistik. Hukum Islam memiliki empat fungsi utama, mencakup landasan ibadah, penegakan kebaikan, penyelenggaraan kehidupan keluarga, dan regulasi masyarakat. Pembentukan hukum Islam bertujuan untuk mencapai kemaslahatan manusia dengan memastikan pemenuhan kebutuhan dasar, kebutuhan sekunder, dan aspek pelengkap yang meningkatkan kesejahteraan.Korelasi yang mendalam antara hukum Islam dan pembinaan masyarakat terletak pada perannya dalam membentuk komunitas yang adil, sejahtera, dan bermoral. Hukum Islam bukan hanya sebagai panduan hukum, melainkan juga sebagai pedoman untuk menciptakan lingkungan yang memberdayakan. Selain itu, hukum Islam menjadi landasan bagi nilai-nilai pendidikan dan merangsang semangat pencarian ilmu pengetahuan, menjadikannya pijakan utama dalam membangun masyarakat yang berintegritas.
A Critical Analysis of Kushthaghna Dravyas Mentioned in Sushrutokta Gana with Commentators View on Controversial Drugs
Authors: Udit Verma  , Rashmi Srivastava  , Priyal Patel  , Sunil Sharma
Published: January 2024

Ayurveda is one of the oldest medical systems with a holistic approach to health and individualize medicine. All the skin diseases in Ayurveda have been discussed under the broad heading of Kushtha. The literal meaning of Kustha is “Kushnati tad vapuhu” which means the Roga which causes discoloration, disfiguration. Acharya Charaka, Sushruta, and Vaghbhata mentioned Kushthghna Dravyas (drugs acting on skin diseases) in their books respectively. Sushruta Samhita is one of prime compendium of Ayurveda where various categorization (Gana) of drugs acting according to different ailments is mentioned in Sutrasthana 38th chapter named Dravyasangrehniya-adhyaya. The objective of the present article is to study the drugs which are mentioned in the category of the drugs which acts on Kushtha (Kushthghna), with their chemical constituents, and pharmacological actions with special reference to Sushruta Samhita and other related books. Rasa-panchaka, botanical names with family, contraversial identification according to commentator’s views are also discussed for better understanding of Dravyas. The review concluded that herbs mentioned in Ayurveda (Sushrutokta Gana) are beneficial in skin diseases and cosmetics in one or another way and also this article will help Ayurvedic UG/PG students, PhD scholars and Ayurveda physicians in both academics and clinical aspect.
A Clinical Study to Evaluate the Efficacy of Patoladi Kwatha along with Navaka Guggulu in Polycystic Ovarian Syndrome with special reference to Artavakshaya
Authors: Sonu Mariam Rajan  , Rachana H. V
Published: January 2024

Polycystic ovarian syndrome is a systemic, endocrinal and also a metabolic disorder and it is the most common cause of hyperandrogenic chronic anovulation occurring in reproductive age group. Acharya Kashyapa mentioned about Pushpagni jataharini, it bears some resemblance with symptoms of PCOS. But most of the symptoms seen in this disease are related to the Artavavaha srotas. The factors which vitiate Kapha, Vata, and Meda have a considerable role in this disease. So here an attempt has been made to work on the efficacy of Patoladi Kwatha along with Navaka Guggulu in PCOS, as it is mentioned that Patoladi Kwatha is Hitakara for Andadhara roga in Andadhaara roga chikitsa adhyaya of Bhaishajya Ratnavali. Methods: Convenient sampling and interventional analytical experimental study were carried out for 30 patients fulfilling the diagnostic criteria for PCOS. Group A with Patoladi kwatha along with Navaka guggulu and Group B with Varunadi kwatha along with Kanchanara guggulu were given for 60 days and 30 days follow up also done by drug free period. Results: In group A, 60% had moderate improvement and 40% had marked improvement from PCOS. In group B, 46.66% had moderate improvement and 53.33% had minor improvement from PCOS. Conclusion: Polycystic Ovarian syndrome, the term itself indicates more than one symptom and hence possibility for multisystem involvement with ovarian dysfunction. The factors which vitiate Kapha, Vata, and Meda have a considerable role in this disease. So, to treat this, drugs should have the properties like Ushna, Teekshna guna, Kapha vata hara and Medahara or Lekhaniya karma. The Patoladi kwatha along with Navaka guggulu is having all these properties. Thus, Patoladi kwatha along with Navaka guggulu is superior to Varunadi kwatha along with Kanchanara guggulu for the treatment of PCOS w.s.r to Artavakshaya.
Critical Analysis of Karnakshweda with its Modern Aspect
Authors: Pragati Pandole  , Ch. Ramadevi  , K. Anasuya
Published: January 2024

Shalakyatantra, one of the eight branches of Ayurveda deals with diseases above the level of the clavicle, i.e., Urdhwajatru. In that, there are twenty-eight Karnarogas as described by Acharya Sushruta, Yogratnakara, and Bhavprakasha. Karnaksweda is one of the Karnaroga that resembles Karnanada, but there is vitiation of Pittadi doshas with a predominance of Vata in the channels of Karna, leading to the generation of Venughoshavata, i.e., flute-like sound, because of different etiological factors like Dhatu Kshayaa, Ruksha Bhojana, etc.

In modern science, tinnitus is described as an unwanted auditory perception of internal origin, usually localised, and rarely heard by others. It can be subjective, when experience is of the individual alone, or, less commonly, objective. It, moreover, acts as a symptom rather than a disease with multifactorial etiology. Karnakshweda can be specifically correlated with cochlear synaptic tinnitus, i.e., tinnitus due to inner ear causes. The majority of cases of tinnitus are subjective; objective tinnitus is far less common. Treatment for Karnaksweda is described as the same as for Karnanada, which includes Vatahar Chikitsa, Snehana, Dhoomapana, Karnapoorana, etc., but there is no specific treatment for Tinnitus in modern science because of idiopathic etiopathogenesis. Ayurveda is a more effective science for the management of diseases like tinnitus.
Pengaruh Literasi Bahasa Inggris terhadap Nilai Toefl Mahasiswa
Authors: Latif Dovanda Rahmi , Tri Hapsari Anggita Dyah , Setiaji Bayu
Published: January 2024

Globalization has made English is more important than ever. This article examines the effect of English literacy against toefl score by analyzing utbk Literacy utbk scores with toefl score. According to a positive relationship if the utbk literation liteaki is high, then toefl scores are also high. The purpose of this study is to know the certainty of whether the English literacy affects the toefl score. To get how much interest read or English literacy, it is spreading a questionnaire containing 4 questions related to literacy and English, utbk Literacy UKB scores, and toefl scores. 34 Physics Education Studs C Nogyakarta State University Invasion in this study and obtained 74.3% read to 42.9% unlike the English. Based on data obtained on utbk Literacy UKB scores and toefl scores, those who get low utbk scores (<400) also get low toefl scores (± 300). Instead, those who get a high score of the utbk (> 400) also get a high toefl score (> 425) there as well. Students who get a score of utbk > 600 but the lowe the toefl score (<425) so do not pass the test. On the other hand there are students with utbk score (400  450) get a toefl score ± 480. This is certainly there are several factors that cause the phenomenon.
Analisis Jumlah Prediksi Penyebaran HIV/AIDS di Kabupaten Sidoarjo menggunakan Metode Multiple Linier Regression
Authors: Azizah Risma Nur , Nisak Umi Khoirun , indahyanti Uce
Published: January 2024

Berdasarkan sumber data yang diperoleh dari Dinas Komunikasi dan Informasi Provinsi Jawa Timur, jumlah kasus HIV/AIDS di Indonesia menempati urutan keempat terbanyak yaitu Provinsi Jawa Timur termasuk Kabupaten Sidoarjo. Tujuan dari penelitian ini adalah untuk memprediksi bahwa jumlah penderita HIV/AIDS di Kabupaten Sidoarjo yang semakin meningkat dari tahun ke tahun. Sumber data penelitian ini bersifat privat dari Dinas Kesehatan Kabupaten Sidoarjo. Data yang digunakan adalah dataset pada tahun 2020-2022, yang meliputi atribut dengan hasil prediksi penderita HIV/AIDS positif dengan nilai prediksi pada tahun 2023 yaitu 795,667, pada tahun 2024 934,167, sedangkan pada tahun 2025 1072,667. Data diolah dengan rapid miner menggunakan metode yang dipilih yaitu multiple linier regression berganda, karena data atribut yang dikumpulkan lebih dari satu. Untuk performa model regresi linier berganda yang dihitung dengan uji validasi root mean squared error (RSME) dengan hasil nilai 0.816 yang dimana semakin kecil hasil prediksinya maka semakin valid.
Proposed Marketing Strategy to Increase Sales of SAMI RAOS
Authors:   School of Business Management, Institut Teknologi Bandung, v Reza Agung , Belgiawan Prawira Fajarindra ,   School of Business Management, Institut Teknologi Bandung
Published: January 2024

Ready-to-cook food has become more popular since post-pandemic. Remote work and government regulations to avoid crowds have shaped mealtime routines, making convenience a priority. Ready-to-cook foods are in demand because people want quick, easy meals without disrupting their work schedules. This shift in consumer behaviour favours the ready-to-cook food industry because consumers want fast, convenient meals. Given the ready-to-cook industry’s remarkable progress and resilience in difficult pandemic circumstances, MSMEs are competing to produce products with diverse culinary options to gain an edge in the market. The ready-to-cook food industry offers international, traditional, and health-focused options. SAMI RAOS is a MSME that sells a variety of ready-to-cook foods. The company has been recognized for preserving and promoting Indonesian and Sundanese cuisine, such as baso aci, cuankie, and mie yamin in ready-to-cook form. The objective of this study is to identify the determinants that impact and improve the sales of SAMI RAOS products. This study employed quantitative methods, including consumer analysis, with a sample size of 227 individuals. The questionnaires were distributed online and utilised the Likert scale for measurement. The author employed both internal and external analysis techniques to conduct a comprehensive descriptive analysis of the company. The research employed internal analysis techniques such as Marketing Mix, STP (Segmentation, Targeting, and Positioning), Value Chain Analysis, and VRIO Analysis. The research incorporated various external analysis techniques, including PESTEL analysis, Porter’s Five Forces analysis, competitor analysis, and customer analysis. The data obtained from these analyses will be used to generate a SWOT and TOWS analysis, which will serve as the basis for developing a business solution and implementation plan. According to the research findings, SAMI RAOS needs to make various improvements to its promotional activities and revamp certain management activities in order to strengthen its position in the market, optimize company resources and capabilities, and mitigate external risks.
Coefficient Bounds of Bi-Univalent Function Involving Pseudo-Starlikeness Associatedwith Sigmoid Function Defined by Salagean Operator via Chebyshev Polynomial
Authors:   Department of Mathematics and Computing Science Education,Emmanuel Alayande University of Education, Oyo, Nigeria, A. M. GBOLAGADE, , T. M. ASIRU, ,   Department of Mathematics and Computing Science Education,Emmanuel Alayande University of Education, Oyo, Nigeria, I. T. AWOLERE, ,   Department of Mathematical Sciences,OndoState University of Science and Technology, Okitipupa, Nigeria
Published: January 2024

Some special classes of univalent functions play an important role in geometric function theory because of their geometric properties. Many of such classes have been introduced and studied; some became well known, for example, the classes of convex, starlike, close to convex, strongly convex and strongly starlike functions. Previous studies by Awolere and Oladipupo (2018) now served as motivation and background to investigate certain classes of analytic, univalent and bi-univalent functions in terms of their coefficient bounds involving salagean and sigmoid functions via Chebyshev poynomial. The classes 퐻푛(휆,훽,훾(푠),휙(푧,푡))are newly established classes for which coefficient bounds will be determined. The aim of the present work is to investigate coefficient bound for class 퐻푛(휆,훽,훾(푠),휙(푧,푡))of pseudo-starlikeness associated with sigmoid functions defined by Salagean operator via Chebyshev polynomial, Fekete-szego problem will also be established and the Hankel of the function will be determined
Viksit Bharat Sankalp Yatra: The Health Perspective
Authors: Bano Tanveer , Varghese Anila
Published: January 2024

In 2023, India became the most populated country in the world with a population of 1.42 billion, providing it potential for significant economic growth by leveraging the demographic dividend.(1,2) As India becomes the global super power that the nation has potential to be, it is imperative to prioritize the well-being of the citizens. The government, being the elected representative body of people, holds the responsibility for ensuring the welfare of the masses. The Government of India periodically introduces welfare programs to cater to a diverse spectrum of the population.(3) As per the 2022 Union Budget, there are 740 central sector schemes.(4) The effectiveness of any program lies in its ability to reach its eligible beneficiaries. Unfortunately, several welfare schemes provided by the government do not reach its eligible recipients due to lack of awareness.(5) An information drought occurs, especially in rural areas despite the government’s best efforts in creating awareness through radio, TV, print or online media.(6)
Routine Childhood Immunization: Its health, developmental, economic and social benefits
Authors: Sangma Risa Vernette Nengminza , Rasania Sanjeev Kumar , Vijayan Sruthi Madathiparambil , Mishra Pallavi , Chawale Shubham Vivekanand
Published: January 2024

Introduction: Immunization plays a pivotal role in public health. It is one of the most cost-effective inventions that have helped bring down a significant amount of burden of diseases among under-five children, some of which are now on the verge of extinction. Objective: To assess the diverse benefits of routine childhood immunization. Methodology: A literature review was conducted using electronic database to understand the broader benefits of immunization. Results: Studies have shown that routine childhood immunization have been able to reduce the incidence of influenza and other targeted diseases (diphtheria, Haemophilus influenzae type b, measles, mumps, polio, and rubella) by 17% and 100% respectively. Conclusion: Vaccines are known to have protective and positive health benefit which extends beyond infancy and childhood. It is therefore one of the best strategies in public health to reduce morbidity and mortality and enable child survival.
Community Medicine Outpatient Department: Patient profile and reasons for bypass of lower-level public health facilities
Authors: Kumar Sanjeev , Jain Seema , Varghese Anila , Gautam Neelam S , Gupta Ramesh Chand
Published: January 2024

Background: The General OPD under the department of Community Medicine at LLRM Medical College, Meerut was inaugurated with the vision to improve quality of OPD services by reducing the patient burden and waiting time at specialist OPDs. Aim & Objective: To describe the profile of patients attending the Community Medicine OPD in LLRM Medical College, Meerut and to estimate the extent and reasons for bypass of lower-level public health facility by patients attending the general OPD. Settings and Design: A hospital based descriptive study was conducted in the general OPD. Methods and Material: Data of all patients from 1st July,2023 to 31st August,2023 was collected from the registers maintained in the OPD. A sample of 215 patients were selected by systematic random sampling to study the objective to assess bypass of lower-level public health facility. Statistical analysis used: Descriptive statistics. Results: A total of 2570 patients attended the general OPD from 1st July,2023 to 31st August,2023. Around 12.8% patients required referral to specialist OPDs. Most common presenting complaints were respiratory symptoms (29.8%). It was seen that 58.8% patients had bypassed the lower-level public health system and the most common reasons were non-availability of a facility nearby (26.8%), not satisfied with previous experience (23.7%), non-availability of treatment (21.6%) and investigations (17.5%), and lack of awareness of services available at the public health facility (15.4%). Conclusions: The general OPD serves as a model for other medical colleges to emulate and improve the quality of services at tertiary care centres.
Determinants of Severe Acute Malnutrition in under-five children in Dibrugarh District, Assam
Authors: Ronghangpi Padmashri , Mahanta Tulika Goswami , Boruah Manjit
Published: January 2024

Background: Malnutrition is a major public health problem and leading determinant of morbidity and mortality in under-five children in India. Aim & Objective: To assess determinants of Severe Acute Malnutrition (SAM) in under-five children of Dibrugarh district, to assess knowledge and practice of Infant, Young Child Feeding Practices (IYCF) and to assess the knowledge and practice of identification of SAM of Anganwadi workers. Settings and Design: Dibrugarh district, Assam. Mixed method study. Methods and Material: It was a case-control study that interviewed mothers of children between 6-59 months between June 2021 to May 2022. Using a pre-tested semi-structured questionnaire Interviews of a total of 164 under-five children’s mothers (82 cases and 82 controls)] were done. Qualitative data was also collected by in-depth interviews of Anganwadi workers (AWWs). Statistical analysis used: SPSS version 25.0. Chi-Square test, unadjusted OR for Bivariate analysis and adjusted odds ratio using Multiple logistic regression was calculated. Results: Determinants of severe acute malnutrition were joint family (AOR 3.08, 95% CI 1.02-9.31, p= 0.046); birth weight less than 2.5 kg (AOR 20.6, 95% CI 4.50-94.03, p=<0.0001); mothers with less than 4 antenatal check-ups (AOR 5.13, 95% CI 1.28-29.47, p=0.021); partial immunization (AOR 9.2, 95%CI 1.83-46.59, p=0.007); and irregular utilization of ICDS services (AOR 27.36, 95%CI 5.73-130.66, p=<0.0001). Problems faced by AWWs during service delivery were communication barriers, community resistance during home visits, and increased workload during COVID-19. Conclusions: IYCF practices need to be promoted with screening and growth monitoring for early detection and timely referral of malnutrition along referred back and linkages of services so that home-based and community-based management can be done to prevent severe acute malnutrition.
Impact of COVID -19 on Healthy Life of People in India
Authors: Awasthi Aishwarya , Singh Shivendra Kumar
Published: January 2024

The COVID-19 pandemic is not the first, and certainly not the last, to strike the world. COVID-19 has conjointly been a serious concern in higher-income countries, with several European countries and over eleven million individuals in the Republic of India had been infected with COVID-19. Though some countries and regions are seeing improvements in hospitalization and death rates, COVID-19 remains a significant concern for vulnerable and underserved populations globally. The COVID-19 pandemic is unexampled and heavy, and numerous of the policy measures taken to mitigate and contain it were necessary and comprehensible. Factors associated with difficulty in accessing medicine due to the COVID-19 situation With the diversion of human resources to COVID-19 work, active case finding for TB has been postponed by a number of states in India. Though regulative authorities in many countries have approved one or a lot of COVID-19 vaccines for emergency use, necessary challenges remain in mass manufacturing and distributing vaccines in developing countries. The national authorities need to arrange for the challenges associated with the health of their population coincidental with combating the COVID-19 pandemic. It's unclear, however, whether the twin impacts of COVID-19 and also the health care disruptions have an effect on these people within the semi-permanent.
Siblings On Artificial Intelligence: “It Is All About The Bottom Line, Period!”
Authors: Gupta Divya , Gupta Deepak
Published: January 2024

It may appear to be a wordy jargon but moral compass, ethical compass and legal compass in artificial intelligence are nothing but about the bottom line and the bottom line is whether humans and their systems will co-exist with artificial intelligence or whether artificial intelligence will outlast (outlive) humans and their systems.
Achievement of Maternal Mortality Ratio (MMR) below the National Level in Jharkhand
Authors: Kumar Abhishek , Shikha Swati , Begum Jarina , Ali Syed Irfan
Published: January 2024

An indicator of the reproductive health of women in an area is the maternal mortality rate. A lot of women in the reproductive age range pass away from difficulties during, during, or related to pregnancy, childbirth, or abortion. No matter the length or location of the pregnancy, the World Health Organization defines maternal death as "the death of a woman while pregnant or within 42 days of termination of pregnancy, from any cause related to or aggravated by the pregnancy or its management but not from accidental or incidental causes".(1)
ADAT MAPPACCING PADA MASYARAKAT BUGIS SINJAI, STUDI PERBANDINGAN HUKUM ADAT DAN MAQASHID SYARIAH
Authors: Musafir Musafir , Hadijah Wahid St.
Published: January 2024

Artikel ini membahas tentang perbandingan Maqashid syariah dan hukum adat terhadap adat mappacci yang dilaksanakan di Kabupaten Sinjai kecamatan Sinjai utara. Pokok permasalahn yang akan dibahas adalah bagaimana pengetahuan masyarakat sinjai tentang mappacci, bagaimana pandangan hukum adat tentang mappaccing, kaitan adat mappaccing dengan maqashid syariah dan bagaimana adat mappaccing ini memberikan dampak bagi sebuah pernikahan. Penelitian ini menggunakan jenis penelitian lapangan dan menggunakan pendekatan Syar’i dan pendekatan secara historis. Kemudian untuk metode pengumpulan data menggunakan observasi dan wawancara. Untuk mengetahui hasil pokok permasalahan maka penulis melakukan langkah penelitian kualitatif dengan metode wawancara dengan penduduk, tokoh adat, tokoh masyarakat dan pemerintah setempat. Dari hasil penelitian tersebut  didapatkan data bahwa sebagian masyarakat Kabupaten  Sinjai belum terlalu mengetahui dan memahami tentang adat mappacci tersebut, kemudian hukum adat memandang adat mappaccing merupakan adat yang perlu dilestarikan dan dipertahankan karena alat-alat yang digunakan pada prosesi mappaccing tersebut memiliki arti kiasan yang hampis sama secara keseluruhan tujuannya dengan maqashid syariah, kemudian adat mappaccing sekarang ini sangatlah berdampak pada sebuah pernikahan karena beberapa yang mengetahui dan beberapa yang kurang mengetahui tentang adat tersebut, sehingga hanya yang mengetahui sajalah yang melaksanakan adat tersebut dan yang kurang mengetahui akan bingung apakah mereka memanggil tokoh adat yang tahu lebih atau hanya melakukan sebatas simbolik saja.