bluuebunny/crossref_metadata_2025 huggingface dataset:
Systematic Review of Data Mining in Education on the Levels and Aspects of Education.
Authors: Missah Yaw Marfo , Inusah Fuseini , Ussiph Najim , Frimpong Twum
Published: May 2023

The application of Data Mining (DM) in education is helping educational leadership to make informed decisions. This review seeks to identify the pattern of DM research by looking at the levels and aspects of education. As the core of schooling is Basic Education (BE), the research seeks to find out the degree of application of DM at this level to identify the challenges and prepare learners for higher education. The databases of nine (9) top-ranked publishers namely; Elsevier, Springer, Hindawi, Sage, SAI, IEEE, MDPI, Emerald and Wiley are used to identify the most recent and relevant papers in Educational DM (EDM) published from the year 2017 to 2022 specifically applied to a specific level of education. After careful filtering, only ninety-four (94) articles and conference papers were fit for the specification. The investigations revealed that only 7.45% of the published research works in EDM for basic education, 11.70% for pre-tertiary education and an overwhelming 80.85% for the tertiary level. Lower levels of education are marginalized. Also, the available literature on educational DM concentrates on student performance using attributes such as demographic factors, family socio-economic life, school environment, learner behaviour and psychological factors among others neglecting the availability of resources to facilitate quality tuition. The use of pedagogical tools is necessary for learning to improve quality. The research has revealed both a population gag and a knowledge gap.
CXCL9 and its receptor CXCR3, an important link between inflammation and cardiovascular risks in RA patients
Authors: Shamsi Afsaneh , Roghani Seyed Askar , Abdan Zahra , Soufivand Parviz , Pournazari Mehran , Bahrehmand Fariborz , Vafaei Ali , Salari Nader , Soroush Masood Ghasemzade , Taghadosi Mahdi
Published: May 2023

Background Cardiovascular disease (CVD) is the most common cause of mortality in rheumatoid arthritis (RA), and Inflammation has a decisive role in its pathogenesis. CXCL9 contributes to multi aspects of inflammatory reactions associated with the pathogenesis of CVD. In the current study, we evaluated the association of plasma CXCL9 and CXCR3 gene expression with Cardiovascular risk factors in RA patients for the first time.Material and methods Thirty newly diagnosed, 30 under-treatment RA patients and 30 healthy subjects were recruited in this study. The plasma concentration of CXCL9 and CXCR3 gene expression were measured using ELISA and Real-Time PCR, respectively. The CVD risk was evaluated using Framingham Risk Score (FRS) and Systematic Coronary Risk Evaluation (SCORE).Results The plasma levels of CXCL9 were significantly higher in the newly diagnosed and under-treatment RA patients compared to the control group (P < 0.0001 and P < 0.001, respectively). Also, The CXCR3 gene expression was remarkably elevated in newly diagnosed and under-treatment patients (P < 0.001 and P < 0.01, respectively). The CXCL9 and CXCR3 were remarkably associated with RA disease activity (P = 0.0005, r = 0.436; P = 0.0002, r = 0.463, respectively). The FRS was remarkably higher in newly diagnosed and under-treatment patients (P = 0.014 and P = 0.035, respectively). The CXCR3 gene expression significantly correlated with age, systolic blood pressure, FRS, and SCORE (P = 0.020, r = 0.298; P = 0.006, r = 0.346; P = 0.006, r = 0.349; P = 0.007, r = 0.341, respectively). The CXCL9 plasma concentration had a significant negative correlation with plasma HDL and LDL levels (P = 0.033, r=-0.275; P = 0.021, r=-0.296, respectively).Conclusion CXCL9 and CXCR3 correlates with different variables of CVD in RA.
Hexavalent chromium detoxification by haloalkaliphilic Nesterenkonia sp strain NRC-Y immobilized in different matrices
Authors: Maany Dina Abdelfatah , Wahba Marwa Ibrahim , Abo-Alkasem Mohammed Ibrahim , El-Abd Mostafa A , Ibrahim Abdelnasser Salah Shebl
Published: May 2023

In order to develop a bioprocess for Cr(VI) detoxification in industrial effluent, a previously isolated potent Cr(VI) reducing haloalkaliphilic Nesterenkonia sp strain NRC-Y was immobilized in nine different matrices including natural polymer, modified natural, synthetic and mixtures of natural and synthetic polymers and investigated for Cr(VI) detoxification. Among the tested carriers and immobilization approaches, Nesterenkonia sp NRC-Y cells encapsulated in amidated pectin beads showed highest Cr(VI) reduction efficiency (58.4% of initial Cr(VI) concentration 150 mg/L after 20 h), followed by alginate, alginate-PVA, alginate-PVA-chitosan, PVA-PVP, and PVA respectively. Therefore, amidated pectin was selected for further investigation and immobilization of both whole cells and chromate reductase. Operational stability study revealed that immobilized whole cell was more efficient and stable than immobilized chromate reductase and the free cells retaining about 60%, 27.0% and 11.5% of its initial activity after four successive batches, respectively. The temperature and pH optima for the immobilized cells were 35⸰C and 7.0, respectively. The pH and thermal stability of Nesterenkonia sp NRC-Y cells were significantly enhanced upon immobilization in amidated pectin beads. The developed immobilized biocatalyst was applied for Cr(VI) reduction in industrial effluent samples, and was able to completely reduce Cr(VI) within 4 and 8 h for effluents for initial Cr(VI) concentrations of 10 and 30 mg/L, respectively. To the best of our knowledge, this is the first report about of Cr(VI) detoxification by immobilized Nesterenkonia sp NRC-Y in amidated pectin beads. The developed immobilized biocatalyst is promising and has the potential for large-scale Cr(VI) detoxification application.
Sustainable Production and In-place Utilization of a Liquid Nitrogenous Fertilizer
Authors: Yang Kaiwen , Han Shuhe , Wang Yuting , Yu Yifu , Zhang Bin
Published: May 2023

Efficient production and utilization of nitrogenous fertilizers can increase the food supply to support the dramatic increase of world's population. However, the conventional centralized production and excessive use of solid nitrogenous fertilizers leads to severe waste and environmental pollution. The adoption of liquid nitrogenous fertilizer can maximize the utilization efficiency. Since plants can simultaneously absorb ammonium- and nitrate-nitrogen fertilizer, herein, we propose a two-step relay strategy to sustainably produce NH4NO3 solution for in-place utilization by using air and water as raw materials. This distributed synthesis approach can be easily incorporated into present irrigation systems with controllable fertilizer concentrations for different crops. Furthermore, a techno-economic analysis is conducted to confirm the application potential of this strategy. This perspective provides new insight for the sustainable production and in-place utilization of liquid nitrogenous fertilizers at appropriate concentrations and hopefully promotes the development of smart agriculture.
A textured surface platform for dual-mode temperature regulation in photonic textiles
Authors: Abebe Muluneh G. , Khousakoun Eric , Gidik Hayriye , Mohsenzadeh Elham , Desprez Sylvain , Maes Bjorn
Published: May 2023

Personal radiative heat regulation using photonic textiles can facilitate a decreased energy consumption in buildings by expanding the range of comfortable ambient conditions. Here, we propose a dual-mode photonic design, which modulates the emissivity using a textured membrane that changes its surface structure between flat and wrinkled. The dual nature of the design is achieved through a varying high and low surface emissivity to provide both cooling and heating functions. Theoretical calculations employing a variety of potential materials and geometries predict a substantial thermoregulation potential of the design, with a setpoint window of up to 5.5 °C, which is achieved using a Lambertian surface texture from zinc oxide at the frontal surface. Furthermore, we fabricate a proof-of-concept demonstrating thermal comfort in a setpoint temperature window of about 3 °C, with further room for improvement. This design leverages the concept of diffusing surfaces, well-known in the photovoltaics field e.g., towards a textile application.
A coupled cavity mode sensing scheme using a RF diagnostic field
Authors: Goodwin-Jones Aaron W. , Zhu Haochen , Blair Carl , Brown Daniel D. , vanHeijningen Joris V. , Ju Li , Zhao Chunnong
Published: May 2023

Precise optical mode matching is of critical importance in experiments using squeezed-vacuum states. Automatic spatial-mode matching schemes have the potential to reduce losses and improve loss stability. However, in quantum-enhanced coupled-cavity experiments, such as gravitational-wave detectors, one must also ensure that the sub-cavities are also mode matched. We propose a coupled cavity mode sensing scheme, using a RF diagnostic field tuned to the HG20/LG10 mode frequency. The error signals are derived to be proportional to the difference in waist position, and difference in Rayleigh ranges, between the sub-cavity eigenmodes. The two error signals are separable by 90 degrees of demodulation phase. We demonstrate reasonable error signals for a simplified Einstein Telescope optical design. This work will facilitate routine use of extremely high levels of squeezing in current and future gravitational-wave detectors.
Evaluation of Artificial Intelligence and Efficacy of Audit Practice in Nigeria
Authors: Owonifari Victor Olufemi , Igbekoyi Olusola Esther , Awotomilusi Niyi Solomon , Dagunduro Muyiwa Emmanuel
Published: May 2023

Artificial Intelligence (AI) has become increasingly popular globally as a crucial tool for auditing financial statements, but in Nigeria, the adoption and use of AI tools by auditors is still in its early stages. Attention has been primarily focused on the Big 4 accounting firms, with little attention given to small-scale audit practitioners in Nigeria. This study seeks to examine the impact of AI on audit practice in Nigeria by employing a survey research design. The population of this study comprises 89 accounting firms operating in the Ikeja Local Government area of Lagos State, with a sample size of 62 firms selected using purposive sampling. Data was collected through a well-structured questionnaire, and the reliability of the research instrument was confirmed with a Cronbach Alpha test result of an average of 70%. Descriptive analysis and regression analysis were used to analyze the data, and the results indicated that data mining, machine learning, and image recognition exhibited a significant positive relationship with audit practice in Nigeria. The study concluded that the use of AI will enable auditors to predict future trends and make more informed decisions that focus on improving audit practice. The study recommended constant training of accountants and audit personnel on the use of data mining techniques to improve audit practice, investment in machine learning tools by audit firms in Nigeria, and increased use of image recognition to assist in object classification.
JEL Classification Codes: M42, M49, C451.
Time-varying Determinants of Changes in E-cigarette Relative Harm Perception among US Young Adults
Authors: Li Wei , Osibogun Olatokunbo
Published: May 2023

Background
Current e-cigarette use has increased among young adults in the United States (US) despite a consistent decrease in perceiving e-cigarettes as less harmful than cigarettes over time. This study examined time-varying predictors associated with the changes in e-cigarette relative harm perception over time among US young adults.
Methods
Data were from the 2013–2018 Population Assessment of Tobacco and Health (PATH) Study for young adults (18–24 years). A time-varying effect model (TVEM) was applied to examine the association between the relative harm perception change and the associated time-varying predictors.
Results
Of the 8,427 young adults, the prevalence of those who perceived e-cigarettes as less harmful than cigarettes decreased from 50.3% in Wave 1 (2013–2014) to 27.7% in Wave 4 (2016–2018). Young adults who were male were more likely to perceive e-cigarettes as less harmful than cigarettes over time (OR = 1.58; 95%CI: 1.53–1.64). In addition, the changes in e-cigarette relative harm perception were less noticeable among those with advanced degrees, who had non-combustible smoke-free home rules, who held negative tobacco-related attitudes, and those who were current e-cigarette users or ever used alcohol (all p-values < 0.05).
Conclusions
A decline was observed in US young adults who perceived e-cigarettes as less harmful than cigarettes from the PATH Study across four waves (2013–2018). The study findings underscore the importance of risk communication that focuses on harm perception profiles and the need for appropriate interventions to balance the considerations of e-cigarette use among young adults.
Cardiovascular health (“Life’s Essential 8”), risk of depression and anxiety: a prospective cohort study
Authors: Gao Xu , Liu Shuzhen , Jiang Meijie , Huang Ninghao , Liang Hailun , Zheng Ruimao , Qin Jian , Zhang Zhiyong , Huang Tao
Published: May 2023

Background: There is a growing interest in the linkage of cardiovascular health (CVH) with depression/anxiety but the evidence of the latest “Life’s Essential 8” is scarce. We aimed to evaluate prospective associations of “Life’s Essential 8” CVH score redefined in 2022 with risk of incident depression and anxiety.
Methods: Based on the latest definition of CVH score (“Life’s Essential 8”), we calculated the total score (0-800 points) based on eight components (0-100 points/component) including diet, physical activity, smoking, sleep duration, body mass index, blood lipids, blood glucose, and blood pressure. Hospital records and mental health questionnaires were employed to yield the baseline prevalence and incidence of depression and anxiety. To address potential genetic confounding and gene-CVH interactions, we quantified genetic risk for both disorders using polygenic scores derived from genome-wide association studies.
Results: Participants with a lower CVH score more often experienced depression, anxiety, and either disorder. During the follow-up, 17,554 incident events with symptoms of either disorder were recorded. Per 100-point decrease in CVH score was significantly associated with an increased risk of incident either disorder (Hazard ratio [HR]=1.149, 95% confidence interval [CI]:1.128-1.170), depression (HR=1.232, 95% CI:1.205-1.260), and anxiety (HR=1.045, 95% CI:1.018-1.072). Sleep duration was the key component related to the risk of depression/anxiety by providing much better estimates of the risks of depression/anxiety. A higher genetic risk could further significantly enhance the impact of worsened CVH on the incidences of either disorder and depression.
Conclusions: Poor CVH is a risk factor for the incident late-life depression/anxiety symptoms of middle-aged and older adults and healthy behaviors especially sleep quality could be targeted for the risk assessment and intervention of depression/anxiety.
Client’s Perception of Aquaculture Extension Service in a Selected Sub-District of Bangladesh
Authors: Mamun-ur-Rashid Md. , Hossain Sabbir , Sadat Najmus , Chowdhury Arifur Rahman
Published: May 2023

This study examines the perceived quality of public aquaculture extension services in a selected sub-district of Bangladesh. The SERVPERF scale data were collected from 230 randomly selected fish farmers who resided in the 15 villages under the selected sub-district. The research findings suggest that the aquaculture extension service performs satisfactorily in assurance, responsiveness and tangible dimensions and is relatively low in reliability and empathy. The logistic regression findings confirm that among the dimensions of the SERVPERF, reliability, assurance and empathy can significantly influence the client’s overall satisfaction with the aquaculture extension service. The factor analytic results show that among the 20 statements of SERVPERF, nine statements grouped into three factors can be a viable tool for measuring the quality of aquaculture extension service. This study recommends individualistic client care, the development of extension skills and the intention of the extension agents to provide need-based prompt service and to arrange extension programs considering the client’s convenience.
Tertiary Care for Infertile Couples: Etiological Diagnosis and Conventional Treatment Outcomes in Kisangani, Democratic Republic of the Congo
Authors: Nguma Jean-Didier Bosenge , O'yandjo Antoine Modia , sihalikyolo Juakali , Otuli Noël Labama , Ntokamunda Kadima , Agasa Salomon Batina , Bosunga Katenga
Published: May 2023

Background In sub-Saharan Africa, tubal factors are described as the main etiological factor of infertility. Under these conditions, medically assisted procreation is particularly indicated. However, ART centers are less available. Thus, infertile couples are quickly oriented towards available conventional alternative treatment. The present study aimed to determine the etiological factors of infertility, the outcomes of the therapeutic options offered, and the factors associated with the success of conventional treatment in infertile couples seeking tertiary care in Kisangani.Methods a cross-sectional study was conducted in two tertiary-level health facilities in Kisangani. Consented infertile couples underwent specific examinations necessary for the exploration of infertility and were treated and followed for a minimum of 6 months. The therapeutic option to be offered could relate to the expectant attitude, medical treatment, surgical treatment or transfer to an in vitro fertilization unit. The pregnancy diagnosis was done by ultrasound.Results A total of 272 infertile couples underwent specific examinations, then were treated and followed for a minimum of 6 months. Many determinant causes are mostly linked to wives than husbands. Overall, only 34 women among 211 treated got pregnant during the follow-up period; 61 couples were advised to resort to IVF or adoption, but the couples for whom the expectant attitude was indicated, had immediately rejected it. The patients who therapeutically succeeded at the end of the treatment were those whose age was less than 35 years (OR = 2.27; 95% CI = 1.06–4.87; P = 0.017), the duration of infertility was less than five years (OR = 6.08; 95% CI = 1.79–20.69; P = 0.001) and those with secondary infertility (OR = 6.08; 95% CI = 1.79–20.69; P = 0.001).Conclusion The etiological particularities, with the predominance of tubal factors, do not allow extend effective treatment without ART techniques. This study constitutes a genuine plea to stimulate national policies to take an interest in infertility questions.
Risk Factors for Stroke-Related Functional Disability and Mortality at Felege Hiwot Referral Hospital, Ethiopia
Authors: Tento Tegenu Tessema , Kume Abrham Shiferaw , Kumaso Sebsibe Kuse
Published: May 2023

Background Stroke is one of the leading causes of functional disability throughout the globe. A large number of risk factors are measured in stroke disease studies, but it is often unclear whether all of them are relevant variables and whether the impact of these variables changes over time or remains constant with the rate of transition between various states of functional disability in stroke patients.Method From September 2019 to August 2021, 298 randomly chosen adult stroke patients were studied in the medical ward outpatient department at Felege Hiwot Referral Hospital using a retrospective cohort study design. The Modified Rankin Scale is used to assess functional impairment in stroke patients. A multi-state Markov model was used to analyze multi-state repeated events and terminal events in stroke patients with varying levels of functional impairment.Result The probability of transitioning from poor functional ability to death was 10%, and the probability of recovering to good functional ability was 24%. The average time spent in good and poor functional ability for various levels of independent variables differs according to their risk. The hazed ratio for poor in comparison to good functional ability was 1.54, 1.73, 2.34, 2.74, and 1.52 for various levels of sex, age group, hypertension, atrial fibrillation, and types of stroke. In comparison to poor functional ability, the hazed ratio at various levels of diabetes mellitus and atrial fibrillation was estimated to be 1.95 and 3.39 higher risk for death. Furthermore, at various types of stroke and Glasgow coma scale score levels, the hazed ratio was estimated to be 0.58 and 0.77 lower risks for good versus poor functional ability of stroke patients, respectively.Conclusion Since gender and age are unchangeable or difficult to control, the prevention, early detection, and treatment of hypertension, diabetes mellitus, atrial fibrillation, hemorrhage stroke, and severe brain injury had the strongest association with functional disability and decreased survival time among stroke patients. As a result, all levels of staff engaged in stroke must receive immediate training.
Addition of the barbell hip thrust is effective for enhancing gluteus maximus hypertrophy in young women
Authors: Kassiano Witalo , Kunevaliki Gabriel , Costa Bruna , Nunes João Pedro , Castro-E-Souza Pâmela , Tricoli Ian , Ribeiro Alex Silva , Cyrino Edilson S.
Published: May 2023

There is a heated debate regarding the effectiveness of performing the barbell hip thrust to elicit gluteus maximus hypertrophy. Notably, evidence on this topic is lacking. Therefore, this study aimed to compare the effects of performing 45º leg press and stiff-leg deadlift (L-S) vs. performing 45º leg press, stiff-leg deadlift plus barbell hip thrust (L-S-BHT) on gluteus maximus muscle size. The sample comprised 33 untrained young women randomly separated into 2 resistance training groups: L-S (n = 15) and L-S-BHT (n = 18). The muscle thickness of the gluteus maximus was assessed through B-mode ultrasound before and after 30 resistance training sessions. The resistance training program was carried out over 10 weeks, 3 days·week− 1. Both training regimens elicited significant increases in gluteus maximus muscle thickness from pre to posttraining (P < 0.001). Notably, L-S-BHT had superior augments (L-S-BHT = + 9.3% vs. L-S = + 6.0%, P = 0.016). The current results suggest that performing barbell hip thrust enhances muscle hypertrophy of the gluteus maximus in untrained young women. From a practical perspective, the inclusion of barbell hip thrust should be considered when the prescription aims to optimize the gluteus maximums hypertrophy.
Association between Illness Perception and Medication Adherence in Patients with Diabetes mellitus type II in North Shoa, Zone: Cross-Sectional study
Authors: Eshete Akine
Published: May 2023

Background
Although a good level of illness perception affects medication adherence, the impact of illness perception on medication adherence is still little known. Therefore, this study aimed to investigate the relationship between illness perception and medication adherence in patients with diabetes mellitus type II in North Shoa, Zon
Methods
An institution-based cross-sectional study was conducted from 24 May to 25 June 2022 in the North Shoa zone. The study involved 552 diabetic patients who were chosen at random from four public hospitals. Data were entered into Epi Data V.3.1 and analyzed using SPSS version 22. Data for continuous variables were reported as means of standard deviations and percentages for categorical variables. Descriptive statistic was used to summarize study variables. Binary logistic regression models were used to assess associations between illness perception and medication adherence. In a bivariable analysis, variables with p-values less than 0.20 were put into a multivariable logistic regression model. A p-value ≤ 0.05 and an OR with a 95% CI are considered statistically significant associations.
Results
The result showed adherence to medication and illness perception was 64.4% (95%; CI: 60.1, 67.9) and 54.7% (95% CI: 41.2, 49.4), respectively. The study found that illness perception showed a significant relationship between illness perception and medication Adherence (p < 0.0001. In the adjusted model, illness dimension of consequence (AOR = 3.10, 95% CI: 2.11, 4.55), personal control (AOR = 1.77, 95% CI: 1.20, 2.61), and emotional representation of diabetes (AOR = 2.26, 95% CI: 1.54, 3.32) were significantly related to medication Adherence of type II diabetic patients.
Conclusion
This recent study shows that illness perception has a significant relationship with medication adherence and can lead to significant changes in medication practice. When discussing diabetic self-management, diabetes care practitioners should take into account patients' illness beliefs using psycho-educational approaches
Pairing of holes by confining strings in antiferromagnets
Authors: Grusdt Fabian , Demler Eugene , Bohrdt Annabelle
Published: May 2023

In strongly correlated quantum materials, the behavior of charge carriers is dominated by strong electron-electron interactions. These can lead to insulating states with spin order, and upon doping to competing ordered states including unconventional superconductivity. The underlying pairing mechanism remains poorly understood however, even in strongly simplified theoretical models. Recent advances in quantum simulation allow to study pairing in paradigmatic settings, e.g. in the t-Jt−J and t-J_zt−Jz Hamiltonians. Even there, the most basic properties of paired states of only two dopants, such as their dispersion relation and excitation spectra, remain poorly studied in many cases. Here we provide new analytical insights into a possible string-based pairing mechanism of mobile holes in an antiferromagnet. We analyze an effective model of partons connected by a confining string and calculate the spectral properties of bound states. Our model is equally relevant for understanding Hubbard-Mott excitons consisting of a bound doublon-hole pair or confined states of dynamical matter in lattice gauge theories, which motivates our study of different parton statistics. Although an accurate semi-analytic estimation of binding energies is challenging, our theory provides a detailed understanding of the internal structure of pairs. For example, in a range of settings we predict heavy states of immobile pairs with flat-band dispersions - including for the lowest-energy dd-wave pair of fermions. Our findings shed new light on the long-standing question about the origin of pairing and competing orders in high-temperature superconductors.
Endovenous laser coagulation of varicose veins: evolution continues
Authors: Minaev V. P. , Bogachev V. Yu. , Kaperiz K. A.
Published: May 2023

The article discusses the evolution of the endovenous laser ablation technique for the treatment of varicose vein disease of lower extremities. The history of studies aimed at improving the endovenous laser ablation is provided. The authors described the features of endovenous laser ablation with wavelengths from λ = 0.445 to 1.94 µm, alongside with edge- and radial-emitting working fibers, as well as fibers with radiation absorption at its distal end. The physical and biophysical mechanisms of the most popular to-date method for outpatient treatment of varicose vein disease of lower extremities are reviewed. The propagation process of laser radiation in the scattering medium is described, and the important role of the radiation scattering effect on the depth of its penetration into biological tissues is shown. The processes that take place during endovenous laser ablation are considered. The difference in physical processes that take place during the use of laser radiation mainly absorbed by hemoglobin (hemoglobin-absorbed range) and by water (water-absorbed range) is described. Expedience of simulating the processes that take place during endovenous laser ablation with the use of blood plasma has been substantiated. The blood plasma simulation demonstrated the decisive action of laser-induced boiling on thermal damage to the vein wall, which causes its fibrous transformation. It has been shown that the use of radial-emitting fibres during intense boiling generates steam bubbles around the site of radiation coupling. The contents of such steam bubbles do not absorb radiation, which thus reaches the venous wall, causing its symmetrical thermal damage. The advantages of using water-absorbing radiation with a wavelength of λ = 1.94 µm in conjunction with a radial-emitting fibre have been substantiated.
Modern approaches to the treatment of trophic ulcers of venous etiology: photodynamic therapy
Authors: Khitaryan A. G. , Ledenev A. A. , Orekhov A. A. , Veliev K. S. , Lyapina V. A. , Kuznetsova V. V. , Bondarenko V. N.
Published: May 2023

Chronic venous insufficiency, being the outcome and complication of most diseases of the veins of the lower extremities, is the fundamental cause of the formation of trophic ulcers. Over the past decade, in solving the problem of treating venous trophic ulcers, certain successes have been achieved, both in theoretical and practical terms. The modern concept of curation of patients with trophic ulcers of venous origin involves a reasonable combination of the following methods of treatment: local, including compression, as well as medical, surgical, minimally invasive and additional methods (physiotherapy, photodynamic therapy, etc.). The main goal of the treatment is to eliminate the ulcer, after which measures are taken to correct the underlying cause (chronic venous insufficiency) and prevent relapse. However, the tactics of the most successful treatment of patients with trophic ulcers of venous etiology is still not defined and requires further improvement. In particular, the method of photodynamic therapy, which includes the usage of special drugs - photosensitizers, also deserves to be studied and expanded for clinical use. The mechanism of photodynamic action is based on the ability of photosensitizers to accumulate in microbial and pathological cells. Under local light exposure, the photosensitizer enters an excited state and charges oxygen, which is associated with erythrocyte hemoglobin. Thus, in cells under the influence, a photochemical reaction is triggered, which ensures the formation of singlet oxygen and its free radicals. Reactive oxygen species, in turn, have a damaging effect on pathogenic flora and necrotic tissues. The main advantages of the method are relative simplicity, no risk of developing antibiotic resistance, acceleration of reparative and regenerative processes, and prevention of secondary infection. Thus, photodynamic therapy allows non-invasive, safe and effective optimization of local treatment and preoperative preparation of patients with venous trophic ulcers.
New data on the morphological and anatomical structure, chemical composition and distribution area of a rare species Komarovia anisosperma in Uzbekistan
Authors: Khamraeva Dilovar , Usmonov Mansur , Bussmann Rainer , Khalilova Elvira , Kodirov Ulugbek
Published: May 2023

For the first time, the morphological and anatomical structure of vegetative and generative organs, the localization of secretory ducts in the underground and aboveground parts of the species plants were studied. New GIS technologies were used to elucidate the spatial structure of the rare endemic species Komarovia anisosperma of the monotypic genus Komarovia Korovin of the Apiaceae family. The performed analysis showed the most significant diagnostic features of the studied organs, such as a deep taproot system, the presence of a multi-branched caudex, underdeveloped stem leaves or stem leaves reduced to sheaths, the central cylinder of the main root showing separate concentric circles of large and small vascular bundles, the presence of numerous secretory ducts in the secondary root cortex, strongly elongated palisade leaf cells etc. As a result of phytochemical study, extracts of Komarovia anisosperma roots and inflorescences were analyzed. According to our data, the main component of underground organs from terpenes was α-muurolene, and for inflorescences it was α-curcumene. Grid mapping showed that the species is mainly concentrated in the Samarkand and Kashkadarya regions, where the most favorable conditions for its growth are found. These areas are the natural area of origin of the species, and the establishment of a protected natural area has led to an increase in the number of natural populations.
The prospects for Symbiogenetics: emergence of superorganismal genomes and reconstruction of cellular evolution (mini-review)
Authors: Provorov Nikolay , Tikhonovich Igor
Published: May 2023

The superspecies systems of heredity that arise via coevolution of nonrelated organisms are represented as the subjects of Symbiogenetics, a new research field addressing integration of the heterologous genomes. Evolutionary mechanisms responsible for this integration include: a) interspecies altruism based on the symbionts' refusal from autonomous existence; b) inheritance of symbionts by hosts as of acquired genetic determinants (pangenesis). Under impacts of these factors, endosymbionts may be transformed into the cellular organelles that have lost biological and genetic individuality and sometimes lack their own genomes. The genomically truncated organelles that have retained the abilities for reproduction and metabolism are considered as the models to reconstruct the early stages of cell evolution, including the emergence of its genome.
O gestor nas unidades básicas de saúde no Brasil: uma revisão da literatura
Authors: Izaguirre Jane Maria , Nugem Rita de Cassia
Published: May 2023

A Atenção Primária em Saúde (APS) é formada pelas Unidades Básicas em Saúde (UBS) e Unidade de Saúde da Família (USF). A APS funciona como principal porta de entrada para a Saúde no âmbito do Sistema Único de Saúde (SUS), definindo-se por um conjunto de ações ligadas à saúde da população em que está inserida. Nesse contexto, encontra-se o gestor de UBS, função criada recentemente. O objetivo deste estudo é realizar uma revisão integrativa da literatura sobre a produção científica nacional, no período de 2000 a 2020, quanto aos principais problemas encontrados e enfrentados pelo gestor da Atenção Primária em Saúde (APS).  Trata-se de uma revisão integrativa da literatura acerca dos problemas enfrentados pelo gestor de APS no âmbito do SUS, no período de 2000 a 2020. Para a seleção dos artigos, foi realizada uma busca nas bases de dados: National Library of Medicine, National Institute of Health - USA (PUBMED), Scientific Eletronic Library online (SciELO) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), e na Biblioteca Virtual de Saúde: (BVS-BIREME). A pesquisa demonstrou que existem problemas em todas as UBSs, percebidos de maneira diferente pelos agentes responsáveis pela gestão. Apesar dos problemas percebidos de forma diferente pelos gestores e, que não haja um consenso sobre o assunto, existem propostas que podem preparar o gestor para enfrentar os problemas encontrados.
O Enfermeiro na triagem neonatal
Authors: Santos Larissa Christiny Amorim dos , Ribeiro Wanderson Alves , Alves Ana Lúcia Naves , Amaral Fernando Salgado do , Fassarella Bruna Porath Azevedo , Arnaldo Clarissa Rosa de Oliveira
Published: May 2023

O Programa Nacional de Triagem Neonatal, que integra a triagem neonatal biológica, auditiva e ocular, foi criada no Brasil em 1992 e tornou-se obrigatória em 2001. Sendo ela capaz de detectar inúmeras doenças precocemente e assim, ser possível tratar sem causar danos irreversíveis a saúde do recém-nascido. A pesquisa refere-se a um estudo reflexivo sobre as contribuições da enfermagem na triagem neonatal, ressaltando a importância dos mesmos que atuam na realização do exame e também na disseminação de informações relevantes a respeito dessa realização no período certo e da forma correta. Os dados utilizados foram coletados da Biblioteca Virtual de Saúde (BVS) nas bases de informações LILACS, BDENF, MEDLINE e SCIELO que serviu como fundamento para embasar o estudo. Esse programa é caracterizado por inúmeras qualidades e projetos para que todas as crianças possam ter acesso a esse exame. Porém, ainda podemos perceber que existe uma grande problematização acerca das questões geográficas, políticas econômicas, sociais, culturais e educacionais. Evidenciou-se assim, a importância de incentivar os profissionais da saúde, principalmente os enfermeiros, no que se refere ao aprimoramento e aquisição de novos conhecimentos nesta área através de programas de educação permanente e continuada em serviço, com intuito de diminuir as falhas que possam ocorrer durante esse processo.

Palavras-chave: Assistência Integral à Saúde; Recém-Nascido; Enfermagem.
Cuidado de enfermagem em oncologia pediátrica: um olhar sobre o ser criança em tratamento oncológico
Authors: Dias Lilian Laine da Conceição , Santos Isabel Cristina Morais dos , Santos Larissa Christiny Amorim dos , Ribeiro Wanderson Alves
Published: May 2023

O câncer impõe desconsolação e diversas expectativas que modificam a vida da criança e do seu familiar. Sendo assim, a enfermagem com toda sua essência de cuidar com sensibilidade deve proporcionar um relacionamento interpessoal, transmitindo sentimento de ajuda e confiança. Desta forma torna-se considerável descrever a relação do cuidado sensível da enfermagem frente ao tratamento oncológico pediátrico. Diante deste contexto o estudo buscou por meio de pesquisa bibliográfica com abordagem qualitativa, tendo como referência e objeto de estudo, o cuidado sensível prestado pelo enfermeiro a criança oncológica. Conclui-se então que a prática do cuidado sensível, tanto para nós enfermeiros quanto para equipe de trabalho é de grande importância, pois podemos reconhecer que a interação e a sensibilidade no ato de cuidar podem ser utilizadas como uma prática terapêutica.
Palavras-chave: Oncologia; Enfermagem Sensível; Enfermagem Pediátrica; Cuidado Sensível.
Educação em saúde com adolescentes de colégio universitário
Authors: Silva Jorge Luiz Lima da , Barbosa Kevin Sousa , Tavares Gustavo Martins Lemos , Collier Luciana dos Santos , Silva Natalia Barbosa da , Loreto Carla da Silva
Published: May 2023

Objetivo: descrever as experiências de acadêmicos de enfermagem de ensino teórico prático em colégio universitário. Método: pesquisa descritiva, do tipo relato de experiência. Palestras e dinâmicas foram utilizadas para fixar os conteúdos requeridos junto a temas mais solicitados como prevenção de infecções sexualmente transmissíveis; sexualidade na adolescência e saúde mental. Ocorreram três encontros, um de sensibilização e interação no recreio, uma palestra e roda de conversa para retirada de dúvidas com aproximadamente 160 estudantes do ensino médio, entrega de materiais e apresentação de apps desenvolvidos como recursos. Conclusão: foi possível constatar a íntima relação entre o ensino, pesquisa, extensão e inovação inseridos em dinâmicas de educação em saúde que é uma competência do enfermeiro. Observou-se a importância da dinâmica interdisciplinar em colégios, assim como a atuação do setor de saúde, atendendo os preceitos do programa saúde na escola.
Palavras-chave: Enfermagem; Saúde Coletiva; Adolescência; Educação em Saúde.
Ciência & Saúde UFF: conteúdos sobre saúde e minicursos on line para comunidade
Authors: Silva Jorge Luiz Lima da , Messias Claudia Maria , Amorim Jeisse de Souza , Santos Daiana Alves dos
Published: May 2023

Introdução: a iniciativa visa promover a educação em saúde como estratégia potencializadora da assistência integral à saúde e trabalha para a produção e divulgação de materiais de ensino, pesquisa e extensão. Este estudo objetiva descrever as atividades desenvolvidas no projeto Ciência & Saúde UFF.  Método: trata-se de relato de experiência das atividades realizadas, desde a criação da ação. Os temas surgem de comentários do YouTube, redes sociais, formulários de avaliação dos cursos (google forms), e e-mails. Resultados: o projeto foi criado inicialmente para disseminar resultados de pesquisas e vídeos curtos sobre educação em saúde e, atualmente vem ganhando destaque e alcance, devido ao oferecimento de cursos, treinamentos e oficinas online, de forma gratuita e de acesso livre. Em 2022, foram produzidos 29 vídeos educativos minicursos/palestras de diversas temáticas relacionadas. Discussão: a iniciativa busca divulgar a produção de conhecimento de ensino, pesquisa e extensão na forma de minicursos, palestras online, e vídeos informativos, com a intenção de sanar as dúvidas comuns da população acerca de diversos temas da área da saúde. Considerações finais: mesmo com os desafios enfrentados em época de pandemia e isolamento social, as atividades vêm sendo realizadas de forma remota, contando com participantes de todo o Brasil.
Palavras-chave: Saúde Coletiva; Qualidade de Vida; Educação; Comunicação.
As infecções sexualmente transmissíveis em idosos maiores de 60 anos de idade
Authors: Medeiros Rejane Guedes de , Gonçalves Sebastião Jorge da Cunha , Alves Manoela , Rodrigues Lilia  Marques Simões , Carreiro Mônica de Almeida , Santos Margarida Maria Donato dos
Published: May 2023

Introdução: As Infecções Sexualmente Transmissíveis (IST) estão entre os problemas de saúde pública mais comum em todo o mundo. Os idosos consistem em um público amplamente vulnerável às IST’s. Assim, essa pesquisa teve como objetivo geral identificar a causa e fatores para o aumento das ISTs pessoas acima de 60 anos de idade e analisar a conduta que se deve aplicar para a diminuição do índice epidemiológico. Materiais e Métodos: Foi realizada então uma revisão sistemática da literatura por meio de um levantamento bibliográfico. Resultados e Discussão: Foi possível identificar que o aumento nas ISTs, em especial o HIV, se deve à falta de conscientização e informações dos idosos a respeito do assunto. Ademais, quanto a conduta empregada para minimizar o índice epidemiológico, constatou-se que a educação voltada para a prevenção é a melhor maneira de reduzir os casos de HIV em idosos. Ainda, é precisa criação de programas e políticas que visem prover apoio social aos idosos no enfrentamento da doença. Considerações finais: Constatou-se a demanda por mais educações preventivas, políticas públicas e programas sociais para apoio aos idosos com HIV.
Palavras-Chave: Aids; HIV; Idosos.
Percepções de pós-graduandos de enfermagem sobre os cuidados paliativos oncológicos e as atribuições da espiritualidade
Authors: Silva Rithiely Rosa Feital da , Pereira Eliane Ramos , Silva Rose Mary Costa Rosa Andrade
Published: May 2023

Trata-se de uma nota prévia de estudo fenomenológico, a ser desenvolvido em Unidade Hospitalar de Cuidados Paliativos, pertencente a um Centro de Referência de Assistência de Alta Complexidade em Oncologia do Ministério da Saúde, localizado na cidade do Rio de Janeiro, cujo objetivo principal é desvelar a percepção dos residentes e Fellow de enfermagem sobre a formação prática em cuidados paliativos oncológico e articulações da espiritualidade; como apoio, à construção de um ebook, facilitador na formação pedagógica. Os participantes da pesquisa são enfermeiros residentes e pós-graduandos de enfermagem nos moldes fellow em cuidados paliativos. O instrumento utilizado será um questionário semiestruturado. A discussão será baseada na teoria de Merleau Ponty, que descreve a percepção como um evento que edifica uma vida pessoal com base no mundo percebido. O estudo obteve parecer favorável do Comitê de Ética em Pesquisa. Espera-se que a pesquisa venha contribuir para estudos futuros sobre o tema, além dos avanços científicos na construção de ferramentas que facilitem o processo educativo em oncologia paliativa, bem como o fortalecimento da linha de pesquisa Formação Pedagógica em Saúde na medida em que os cuidados paliativos exigem uma melhor qualificação diante da complexidade da formação especializada neste campo de ensino prático.
Palavras-Chave: Cuidados Paliativos; Formação de Recursos Humanos em Saúde; Enfermagem; Oncologia.
reflexão do papel da enfermagem na dimensão espiritual e suas implicações para a saúde
Authors: França Luiz Carlos Moraes , Gomes Juliana Rodrigues da Silva , Costa Marcelle Bezerra da , Gomes Rafaela da Conceição , Gomes Antonio Marcos Tosoli , Souza Karen Paula , Couto Pablo Luiz Santos
Published: May 2023

Objetivo: refletir a dimensão espiritual do indivíduo, analisando os conteúdos que integram o cuidado, suas implicações na saúde da pessoa e o papel que a enfermagem exerce para o cuidado espiritual. Conteúdo: trata-se de um estudo de análise reflexiva, em busca nas bases de dados encontradas na Biblioteca Virtual em Saúde (BVS). Os descritores utilizados foram espiritualidade AND enfermagem AND cuidado em saúde AND dimensão espiritual. Foram obtidos 26 estudos, nos idiomas inglês, português e espanhol, publicados nos últimos 10 anos (2012-2021). Após avaliação de títulos e resumos, um total de 12 artigos foi considerado para análise. Estudos sobre espiritualidade e seus benefícios na saúde vem ganhando força ao longo dos anos, mas ainda se faz necessário o conhecimento sobre espiritualidade pelas equipes multidisciplinares, destacando os profissionais da enfermagem. Conclusão: A dimensão espiritual traz resultados satisfatórios na vida daqueles que conseguem desenvolver sua espiritualidade no processo saúde-doença.
Palavras-Chave: Espiritualidade; Enfermagem; Cuidado em Saúde; Bem estar Espiritual.
Aplicação do Arco de Maguerez na promoção e educação em saúde bucal: relato de experiência
Authors: Paiva Carina de Souza , Maluf Fabiano , Coelho Letícia de Amorim Mota , Nunes Caroline Jonas Rezaghi Ricomini
Published: May 2023

A introdução de metodologias ativas como estratégias de ensino e promoção de saúde busca oferecer um processo de aprendizagem mais crítico e autônomo. Esse estudo teve como objetivo relatar a experiência da aplicação do Arco de Maguerez para o desenvolvimento de atividades em grupo, com foco na promoção da saúde oral de crianças em idade escolar, destacando a importância do autocuidado para a prevenção da doença cárie. A trajetória foi desenvolvida em cinco etapas: (1) observação da realidade, (2) pontos chave, (3) teorização, (4) hipóteses de solução e (5) aplicação à realidade. A realização desse projeto permitiu a reflexão sobre o papel da equipe de saúde bucal inserida na Estratégia de Saúde da Família na garantia de cuidado para além da intervenção clínica. Os resultados demonstram a importância do desenvolvimento de atividades coletivas para educação e promoção em saúde, fortalecendo o vínculo com a população adscrita no território.
Palavras-chave: Estratégia de Saúde da Família; Educação em Saúde; Aprendizagem Baseada em Problemas; Saúde bucal.
Cattle Disease Studies Via Geographical Information System in Bowi Subur Village, Masni District, Manokwari Regency, West Papua Province
Authors: Timur Ni Putu Vidia Tiara , Syaefullah Bangkit Luthfiaji , Labatar Susan Carolina , Bachtiar Ebit Eko
Published: May 2023

Geographical Information System(GIS) and remote sensing provide real-timedata to stakeholders.GIS is new and modern tool that are essential for mapping, monitoring, and surveillance of animal diseases.This study aims to provide a digital map of cattlepopulation and diseasedistribution. Usingsatellite imaging as mapping apparatus, this study map the distribution of cattle diseases.Animal health is key to livestock production and productivity. This study can be used as prevention and treatment measures efficiently and effectively.Based on theresults of the study, the cattle population in Bowi Subur Village was 455 heads. About 78% of respondents grazetheir cattle extensively in a forage land while the other 22% keeptheir cattle intensively in the barn,31 respondents (31%) stated that their cattle had health problems.The study showed that cattle diseases, such as helminth infestation, external parasite infestation, dystocia, and abortus, are varied. Both primary and secondary data showed that helminth infestation was the most common case. Bowi Subur Village has great potential for animal husbandry development especially ruminantsin Manokwari Regency.