bluuebunny/crossref_metadata_2025 huggingface dataset:
Copper binding and protein aggregation: a journey from the brain to the human lens
Authors: Posadas Yanahi , Sánchez-López Carolina , Quintanar Liliana
Published: October 2023

Metal ions are implicated in many proteinopathies. Three case studies are discussed to address how copper binding impacts protein folding and aggregation, and its relevance in understanding the polymorphic nature of the aggregates related to disease.
Tracking the super resolved structure of mitochondria using red emissive carbon nanodots as a fluorescent biomarker
Authors: Garg Richa , Anjum Farhan , Salam Abdul , Kaushik Kush , Sharma Shagun , Sahrawat Udisha , Yadav Aditya , Nandi Chayan Kanti
Published: October 2023

Observation of morphological changes in mitochondria under various conditions using red emissive carbon nano dots.
meta-Fluorophores: an uncharted ocean of opportunities
Authors: Chatterjee Tanmay , Mandal Mrinal , Mardanya Sukumar , Singh Manjeev , Saha Arijit , Ghosh Swarnali , Mandal Prasun K.
Published: October 2023

meta-fluorophores hold the promise to create an uncharted ocean of hitherto unachieved opportunities.
A foldable self-healing rocking chair zinc-ion battery using a three-dimensional zinc metal-free anode
Authors: Long Jiawei , Han Tianli , Lin Xirong , Zhu Yajun , Liu Jinyun
Published: October 2023

H2Ti5O11·xH2O/carbon cloth was developed as a Zn metal-free anode for high-performance zinc-ion batteries. The as-assembled battery delivered stable capacities at different angles, which is significant for foldable and wearable batteries.
Exploring the biointerfaces: ab initio investigation of nano-montmorillonite clay, and its interaction with unnatural amino acids
Authors: Fernando Ashan , Khan Desmond , Hoffmann Mark R. , Çakır Deniz
Published: October 2023

We investigated the interaction between biomimetic Fe and Mg co-doped montmorillonite nanoclay and eleven unnatural amino acids.
Spatially isolating Li+ reduction from Li deposition via a Li22Sn5 alloy protective layer for advanced Li metal anodes
Authors: Xie Jia , Xue Jing , Wang Hongyi , Li Jingze
Published: October 2023

A Li22Sn5 alloy layer on Li metal anodes enables spatial separation of the reduction sites of Li+ from Li nucleation/growth sites.
Bacterial model membranes under the harsh subsurface conditions of Mars
Authors: Tortorella Attila , Oliva Rosario , Giancola Concetta , Petraccone Luigi , Winter Roland
Published: October 2023

The deep subsurface of Mars is thought to harbor high concentrations of chaotropic salts in brines. Perchlorate salts were found to favor the physiologically relevant fluid-like phase of bacterial membranes even under high-pressure stress.
Enhanced hydrogen evolution reaction performance of anatase–rutile TiO2 heterojunction via charge transfer from rutile to anatase
Authors: Arzaee Nurul Affiqah , Yodsin Nuttapon , Ullah Habib , Sultana Sabiha , Mohamad Noh Mohamad Firdaus , Mahmood Zuhdi Ahmad Wafi , Mohd Yusoff Abd Rashid Bin , Jungsuttiwong Siriporn , Mat Teridi Mohd Asri
Published: October 2023

In light of recent doubts surrounding the industrial viability of photo(electro)catalysis technology for sustainable hydrogen production, it becomes imperative to align materials development with rationalized synthesis protocols.
First comparison of catalytic CO2 reduction to CO over molybdenum carbide, nitride and phosphide catalysts
Authors: Rong Qingshan , Ding Wei , Liu Guogang , Zhang Zhiqiang , Yao Zhiwei
Published: October 2023

The nitrided Mo/CNT catalyst can show comparable reverse water gas shift (RWGS) performance to the bimetallic Cu/β-Mo2C catalyst under similar conditions.
Understanding photocatalytic hydrogen peroxide production in pure water for benzothiadiazole-based covalent organic frameworks
Authors: Wang Linyang , Sun Jiamin , Deng Maojun , Liu Chunhui , Ataberk Cayan Servet , Molkens Korneel , Geiregat Pieter , Morent Rino , De Geyter Nathalie , Chakraborty Jeet , Van Der Voort Pascal
Published: October 2023

In this study, we introduce two benzothiadiazole-based COFs with tunable electronic structures and electron affinities for photocatalytic H2O2 production.
Best practice for sampling in automated parallel synthesizers
Authors: Ringleb Michael , Schuett Timo , Zechel Stefan , Schubert Ulrich S.
Published: October 2023

The current sampling method for automated parallel synthesizers is reviewed with special focus on the sealing of sampling vessels and new best practice for automated sampling for, e.g., SEC or GC is established.
Impact of noise on inverse design: the case of NMR spectra matching
Authors: Lemm Dominik , von Rudorff Guido Falk , Anatole von Lilienfeld O.
Published: October 2023

The effectiveness of computational NMR spectra matching for inverse structure elucidation depends on the interplay of number of candidates, chemical shift accuracy, as well as the usage of multiple shift types.
Electrochemical generation of high-valent oxo-manganese complexes featuring an anionic N5 ligand and their role in O–O bond formation
Authors: Biswas Sachidulal , Chowdhury Srijan Narayan , Lepcha Panjo , Sutradhar Subhankar , Das Abhishek , Paine Tapan Kanti , Paul Satadal , Biswas Achintesh N.
Published: October 2023

High-valent oxomanganese transients featuring a redox-active anionic N5-ligand are successfully engendered through the electrochemical oxidation of the corresponding hydroxomanganese(iii) complex.
Coordination polymers: a promising candidate for photo-responsive electronic device application
Authors: Dutta Basudeb , Ahmed Faruk , Mir Mohammad Hedayetullah
Published: October 2023

This study emphasizes recent advances in the designing of coordination polymers for photo-responsive electronic device applications in regard to crystal engineering aspects and structure–property relationship.
Functional guild dynamics in a single-sludge shortcut nitrogen and phosphorus removal reactor: a modeling study
Authors: Yuan Quan , Jia Zhen , Roots Paul , Sabba Fabrizio , Wells George
Published: October 2023

A mathematical process model was set up to evaluate functional guild dynamics in an integrated N and P removal process.
Effects of different microwave power on the drying kinetics and physicochemical quality of brown shrimp (Metapenaeus dobsoni)
Authors: Verma Sumit Kumar , Sasikala Remya , Kishore Pankaj , Mohan C. O. , Ganesan P. , Padmavathy Pandurengan , Muralidharan Nagarajan , Jaganath Bindu , Benjakul Soottawat
Published: October 2023

Microwave processing is used in industry for drying food commodities as it improves the quality of products and reduces the drying period.
Flexible, antibacterial porous phase change thermal management film prepared by a one-step extrusion casting-foaming method
Authors: Guo Xinyu , Xing Tianyu , Huang Yanqin , Feng Jiachun
Published: October 2023

A SEBS/paraffin/PP phase change foaming film was prepared through a one-step melt extrusion casting-foaming technology, and its application potential in thermal therapy was demonstrated.
Research status of indole-modified natural products
Authors: Duan Song-Fang , Song Lei , Guo Hong-Yan , Deng Hao , Huang Xing , Shen Qing-Kun , Quan Zhe-Shan , Yin Xiu-Mei
Published: October 2023

Indole is a heterocyclic compound formed by the fusion of a benzene ring and pyrrole ring, which has rich biological activity.
Capping layer enabled controlled fragmentation of two-dimensional materials by cold drawing
Authors: Chen Ming , Li Dong , Hou Yuxin , Gu Mengxi , Zeng Qingsheng , Ning De , Li Weimin , Zheng Xue , Shao Yan , Wang Zhixun , Xia Juan , Yang Chunlei , Wei Lei , Gao Huajian
Published: October 2023

This study gives an accurate understanding of interactions between 2D materials, polymer substrates, and capping layers during cold drawing, and offers guidance for potential applications such as flexible electronics.
Looking back over 10 years of Materials Horizons
Authors: Stenzel Martina H
Published: October 2023

Current Editorial Board Chair Martina Stenzel reflects on the last 10 years of the journal in celebration of the 10th anniversary of Materials Horizons, looking back at her time as Scientific Editor, and now Chair of the Editorial Board.
Ex vivo transdermal delivery of 3H-labelled atovaquone solid drug nanoparticles: a comparison of topical, intradermal injection and microneedle assisted administration
Authors: Morris Sam , Long Mark , Savage Alison , Owen Andrew , Rannard Steve , Cauldbeck Helen
Published: October 2023

Ex vivo transdermal permeation and deposition of atovaquone solid drug nanoparticles. Topical administration exhibited limited penetration, intradermal injection delivered a burst release and the microneedle assisted route offered sustained delivery.
A layered-spinel heterostructure 0.5NaMnO2–0.5Li0.5Mn2O4 cathode for advanced lithium ion batteries
Authors: Gao Tianfeng , Cai Yanjun , Kong Qingrong , Tian Hualing , Yao Xiang , Su Zhi
Published: October 2023

A heterostructure NaMnO2–Li0.5Mn2O4 cathode is proposed and investigated by in situ XRD and impedance analysis. The structural stability and migration rate in layered NaMnO2 were effectively improved, which exhibited excellent cycling performance.
Isonicotinate-Zn(ii)/Cd(ii) bridged dicobaloximes: synthesis, characterization and electrocatalytic proton reduction studies
Authors: Yadav Jitendra Kumar , Mishra Anjali , Mishra Gaurav Kumar , Pal Sarvesh Kumar , Narvekar Kedar Umakant , Rahaman Ahibur , Singh Nanhai , Lama Prem , Kumar Kamlesh
Published: October 2023

Dicobaloxime complexes bridged by isonicotinate-Zn(ii)/Cd(ii) moieties are synthesized and their electrocatalytic activities are investigated in the proton reduction to molecular hydrogen.
Rapid determination of rebaudioside A content in the macroporous resin elution process using a portable near-infrared spectrometer
Authors: Gao Lele , Wang Difan , Zhong Liang , Yue Jianan , Nie Lei , Li Lian , Meng Zhaoqing , Cao Guiyun , Lai Yuqiang , Zang Hengchang
Published: October 2023

Portable NIR spectroscopy is used to monitor the macroporous resin elution process. The PLSR and SVMR models displayed good performance for determining the RA content. The PLSR model displayed higher predictive accuracy than the SVMR model.
Coupled ion transport in concentrated PEO–LiTFSI polymer electrolytes
Authors: Gullbrekken Øystein , Kvalvåg Schnell Sondre
Published: October 2023

Ionic correlations are important in concentrated PEO–LiTFSI polymer electrolytes. Onsager coefficients are necessary to characterize the ionic motion. Li and TFSI are anticorrelated, increasing the ionic conductivity and Li-ion transport number.
A bi-functional three-terminal memristor applicable as an artificial synapse and neuron
Authors: Liu Lingli , Dananjaya Putu Andhita , Ang Calvin Ching Ian , Koh Eng Kang , Lim Gerard Joseph , Poh Han Yin , Chee Mun Yin , Lee Calvin Xiu Xian , Lew Wen Siang
Published: October 2023

In this work, a gate-controlled memristor that enables synaptic and neuronal bi-functionality is proposed, which enhances neural network hardware implementation efficiently with all standard CMOS techniques used for device fabrication.
Recent advances in electrocatalytic reduction of ambient CO2 toward high-value feedstock
Authors: Fujinuma Naohiro , Lofland Samuel E.
Published: October 2023

The effects of climate change have arisen due to greenhouse gases emitted into the atmosphere, and the finite supply of fossil fuels will eventually be unable to support the needs of the petrochemical industry.
Exploring the effect of the reaction conditions on the mechanism of the photocatalytic reduction of CO2 in the vapor phase over Pt/TiO2: an operando FTIR study
Authors: Dankar Joudy , Rouchon Virgile , Pagis Céline , Rivallan Mickael , El-Roz Mohamad
Published: October 2023

CH4 production enhancement upon periodic irradiation cycles.
Solid hybrid electrolytes based on conductive oxides and polymer electrolytes for all-solid-lithium batteries
Authors: Tian Leiwu , Kim Ji-Wan , Kim Dong-Won
Published: October 2023

This article provides an overview of solid hybrid electrolytes based on Li+-conductive oxide and polymer electrolyte for all-solid-state lithium batteries and discusses their composition, conduction mechanism, progress, and perspectives.
Blue-light induced iron-catalyzed chemoselective α-alkylation and α-olefination of arylacetonitriles with alcohols
Authors: Song Dingguo , Wang Shiliang , Huang Weiwei , Chen Rong , Hu Fangyuan , Cheng Lingxin , Zhao Xianghua , Ling Fei , Zhong Weihui
Published: October 2023

This work describes the blue-light induced iron-catalyzed divergent synthesis of α-alkylated nitriles and α,β-substituted acrylonitriles from arylacetonitriles and alcohols at room temperature.
Nucleophilic organocatalysis involving radical intermediates
Authors: Yang Hai-Bin
Published: October 2023

The recent advancements in single-electron nucleophilic organocatalysis that facilitates single-electron transfer between substrates through the formation of a covalent intermediate were summarized based on the type of catalyst.
Effect of internal oxygen substituents on the properties of bowl-shaped aromatic hydrocarbons
Authors: Takeo Yoshihiro , Hirano Junichiro , Shimizu Daiki , Fukui Norihito , Shinokubo Hiroshi
Published: October 2023

In this study, we compare a bowl-shaped aromatic hydrocarbon with internal methoxy groups to related derivatives with hydrogen, methyl, and anisyl groups, evaluating their electron-accepting properties, electronic absorption spectra, and fullerene-binding behavior.
NiGA MOF-based dispersive micro solid phase extraction coupled to temperature-assisted evaporation using low boiling point solvents for the extraction and preconcentration of butylated hydroxytoluene and some phthalate and adipate esters
Authors: Pezhhanfar Sakha , Farajzadeh Mir Ali , Hosseini-Yazdi Seyed Abolfazl , Afshar Mogaddam Mohammad Reza
Published: October 2023

The first-ever attempt to apply nickel gallic acid metal–organic framework (NiGA MOF) in analytical method development was done in this research by the extraction of some plasticizers from aqueous media.
Manganese vacancies and tunnel pillars synergistically improve the electrochemical performance of MnO2 in aqueous Zn ion batteries
Authors: Huang Lanxiang , Chen Yilin , Deng Pu , Zhao Bo , Luo Xufeng , Chen Chang , Hu Yu
Published: October 2023

Decrease of AOS of Mn and higher BE value of O 1s suggest that doped Nb5+ created Mn vacancies and as tunnel pillars enhanced the stability of MnO2. Both synergistically improved electrochemical performance of MnO2 in aqueous Zn ion batteries.
Recent biological applications of heterocyclic hybrids containings-triazine scaffold
Authors: Ali Muhammad Imran , Naseer Muhammad Moazzam
Published: October 2023

s-Triazine possesses an auspicious status in the field of drug discovery and development. This review is an effort to summarize and highlight recent biological applications of heterocyclic hybrids containings-triazine scaffold.
Harnessing gradient gelatin nanocomposite hydrogels: a progressive approach to tackling antibacterial biofilms
Authors: Zhu Jiawei , Wang Anli , Miao Xingguo , Ye Hui , Pan Shuo , Zhang Chengxi , Qian Qiuping , Su Feifei
Published: October 2023

Gradient gelatin nanocomposite hydrogels based on PDA–Cu nanoparticles and PgelMA hydrogels with high biocompatibility with mammalian cells, making them suitable for wound healing and antibacterial biofilm management.
Asymmetric synthesis of chiral (thio)chromanes and exploration on their structure–activity relationship in macrophages
Authors: Zhang Xiao , Zhou Qian , Zhou Yue , Wang Zihao , Wang Jun , Wang Mingfu
Published: October 2023

A CuCl/(R,R)-Ph-BPE-catalyzed enantioselective hydroallylation of 2H-(thio)chromenes is developed, which enables access to a series of 4-allyl (thio)chromanes in high yields (up to 91%) with excellent enantioselectivities (up to 99% ee).
EnzyKR: a chirality-aware deep learning model for predicting the outcomes of the hydrolase-catalyzed kinetic resolution
Authors: Ran Xinchun , Jiang Yaoyukun , Shao Qianzhen , Yang Zhongyue J.
Published: October 2023

EnzyKR is designed to guide the identification of hydrolase scaffolds for resolving a racemic substrate mixture for stereoselective synthesis.
Polymeric materials for ultrasound imaging and therapy
Authors: Barmin Roman A. , Moosavifar MirJavad , Dasgupta Anshuman , Herrmann Andreas , Kiessling Fabian , Pallares Roger M. , Lammers Twan
Published: October 2023

Ultrasound-responsive polymeric materials with finely tunable physicochemical properties and acoustic responses enable their applications in imaging and therapy, such as functional/molecular imaging, targeted drug delivery, and sonopermeation.
Skeletal rearrangement through photocatalytic denitrogenation: access to C-3 aminoquinolin-2(1H)-ones
Authors: Singh Swati , Chakrabortty Gopal , Raha Roy Sudipta
Published: October 2023

Selective installation of an amino group on heterocyclic ring employing the skeletal editing approach has been explored. We discussed a regioselective denitrogenative amination strategy to access C-3 aminoquinolin-2(1H)-ones utilizing 3-ylideneoxindoles and TMSN3 as an aminating agent.
Turn-off fluorescence of imidazole-based sensor probe for mercury ions
Authors: Krishnan Uma , Manickam Saravanakumar , Kulathu Iyer Sathiyanarayanan
Published: October 2023

A new highly selective and sensitive fluorescent probe, 5 (2-(4-(1,3-dithian-2-yl)phenyl)-4,5-diphenyl-1H-imidazole), was developed for Hg2+ ion with colorimetric and fluorimetric behavior in organic semi-aqueous solutions.
Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter measurement of global haemostasis
Authors: Sarıyer Rüya Meltem , Gill Kirandeep , Needs Sarah H. , Hodge Daniel , Reis Nuno M. , Jones Chris I. , Edwards Alexander D.
Published: October 2023

High throughput, automated, time-lapse imaging for multiparameter haemostasis.
N-doped graphene nanosheets-based optical nano switch for the selective detection of guanine and Pb2+
Authors: Tripathi Vijayendra Kumar , Das Gouri Sankar , Gupta Raju Kumar , Srivastava Manish , Tripathi Kumud Malika
Published: October 2023

N-doped graphene nanosheets synthesised from biomass are used as a PL probe for the on-off-on detection of Pb2+ and guanine.
A deep learning-based framework for battery reusability verification: one-step state-of-health estimation of pack and constituent modules using a generative algorithm and graphical representation
Authors: Park Seojoung , Lim Dongjun , Lee Hyunjun , Jung DaWoon , Choi Yunseok , Lim Hankwon , Kim Donghyuk
Published: October 2023

A non-invasive approach to reveal the health of individual modules, replying on the state-of-health of the battery pack, is achieved through generative adversarial networks (GAN) with spatialized battery pack cycling profiles.
In situ molecule-level interface tailoring of metastable intermolecular composite chips toward on-demand heat release and information encryption
Authors: Guo Xiaogang , Liang Taotao , Tetteh Ankamfio Julius , Islam Md Labu , Huang Huisheng , Yuan Binfang , Cui Xun
Published: October 2023

A promising high-energy nano-Al/MnO2 MIC chip with on-demand heat-release and in situ information recording/encryption was designed, which provides a novel insight for the development of the next generation of smart MIC devices.
Rh for HER electrocatalysis? A critical analysis of recent studies and thoughts on the same!
Authors: Arulraj Roshini , Prabu Rajendran , Sara Fidha C. M. , Eswaran Karthik , Murugesan Rajini , Shanmugan Swaminathan , Maruthapillai Arthanareeswari , Anantharaj Sengeni
Published: October 2023

An opinionated review presenting a critical analysis of the use of Rh as an HER electrocatalyst and the recent developments while highlighting the future directions of the same.
Impact of side-chain deuteration on the molecular stacking and photovoltaic performance of non-fullerene acceptors
Authors: Zeng Liang , Zhang Ming , Gao Mengyuan , Xue Lingwei , Wang Haiqiao , Zhang Zhi-Guo , Ye Long
Published: October 2023

The deuterium isotope effect plays a profound role in semiconductors, here, such effect of side chains on the photovoltaic properties of acceptors was fully explored.
Cobalt modification of nickel–iron hydroxide electrocatalysts: a pathway to enhanced oxygen evolution reaction
Authors: Soo Joshua Zheyan , Riaz Asim , Kremer Felipe , Brink Frank , Jagadish Chennupati , Tan Hark Hoe , Karuturi Siva
Published: October 2023

Synthesis of ternary NiFeCo hydroxide as an efficient OER electrocatalyst using a versatile, two-step solution corrosion approach.
Improving open-circuit voltage deficit by interface passivation via Li treatment in Cu2ZnSn(S,Se)4 solar cells
Authors: Lim Geumha , Park Ha Kyung , Kim Wook Hyun , Kim Seung-Hyun , Yang Kee-Jeong , Kang Jin-Kyu , Kim Dae-Hwan , Jo William
Published: October 2023

Li-doping via LiF post deposition treatment has achieved an enhanced open-circuit voltage in Cu2ZnSn(S,Se)4 solar cells. The Li treatment passivates the defects resulting in the modification of interface band alignment and enhanced charge excitation.
Unraveling mechanistic insights into covalent organic frameworks for highly efficient sequestration of organic iodides from simulated nuclear waste
Authors: Fajal Sahel , Majumder Dipanjan , Mandal Writakshi , Let Sumanta , Dam Gourab K. , Shirolkar Mandar M. , Ghosh Sujit K.
Published: October 2023

A systematic study was conducted to understand the role of framework-integrated functionalities, along with the textural properties, towards organic iodide sequestration by varying the number of N-heteroatomic sites in a series of COFs.
Synthesis of three-component Cu2O/ZnO/Ag nanocrystal heterogeneous photocatalysts with high reactivity and stability for dye reduction
Authors: Chiang Chih-Wu , Lai Chieh-Yu , Hsu Su-Wen
Published: October 2023

Cu2O–ZnO–AgNC nanocrystals can suppress the photocorrosion of Cu2O and ZnO by efficiently utilizing the “active charges” for Congo red reduction. Furthermore, the plasmonic “hot electrons” from AgNC can be used to accelerate the reduction rate.
Self-driven immune checkpoint blockade and spatiotemporal-sensitive immune response monitoring in acute myeloid leukemia using an all-in-one turn-on bionanoprobe
Authors: Zhang Dangui , Wu Honglian , Wang Tianci , Wang Yuting , Liu Sixi , Wen Feiqiu , Oudeng Gerile , Yang Mo
Published: October 2023

An all-in-one bionanoprobe was developed for self-driven immune checkpoint blockade and spatiotemporal-sensitive immune response monitoring in heterogeneous acute myeloid leukemia cells.
Regioisomeric effects of dibenzofuran on the properties of boron–nitrogen multiple resonance emissive materials
Authors: Li Hongyang , Yan Hao , Meng Lingqiang , Zhang Xiaopeng , Kuang Changchun , Meng Zhiming , He Yaowu , Xu Hong , Zhang Xinkang , Zheng Youxuan , Yan Chaoyi , Meng Hong
Published: October 2023

Regioisomeric effects have a profound impact on the OLED efficiency. DABNA-3-DBF demonstrated enhanced PLQY and a EQEmax of 25.9%, showcasing optimized conjugation for greater performance.
CoMnCrGa: a novel ferromagnetic material with high spin-polarization for room temperature spintronics
Authors: Gupta Shuvankar , Chakraborty Sudip , Bhasin Vidha , Pakhira Santanu , Dan Shovan , Barreteau Celine , Crivello Jean-Claude , Jha S. N. , Avdeev Maxim , Bhattacharyya D. , Paul-Boncour V. , Mazumdar Chandan
Published: October 2023

Here, we report the synthesis of a novel quaternary Heusler alloy CoMnCrGa and its structural, magnetic, transport and electronic properties using both experimental and theoretical methods.
Strong and tough conductive PVA hydrogels based on the synergistic effect of acetic acid induction and salting-out for flexible solid-state supercapacitors
Authors: Zhong Weifeng , Song Yufang , Chen Jiwei , Yang Shuai , Gong Lihao , Shi Dongjian , Dong Weifu , Zhang Hongji
Published: October 2023

A synergistic strategy of acetic acid induction and salting-out is proposed for optimizing the microstructure, mechanical properties, and ionic conductivity, thus constructing strong and tough conductive PVA hydrogels for flexible supercapacitors.
Degradable semiconducting polymers without long-range order for on-demand degradation of transient electronics
Authors: Chiong Jerika A. , Michalek Lukas , Peña-Alcántara Amnahir E. , Ji Xiaozhou , Schuster Nathaniel J. , Bao Zhenan
Published: October 2023

Degradable, nanocrystalline semiconducting polymers lacking long-range order are able to degrade orders of magnitude faster than their semicrystalline counterparts.
A julolidine functionalized benzimidazoline n-dopant: optimizing molecular doping in fullerene derivatives by modulating miscibility
Authors: Li Chenglong , Wang Wei , Zhan Chun , Zhou Qisheng , Dong Defu , Xiao Shengqiang
Published: October 2023

A novel n-dopant JLBI-H prepared by replacing the dimethylaniline group of N-DMBI-H with julolidine was found to be favorable for doping solution-processed fullerene derivatives bearing alkyl side chains.
Impact of altitude on spring macroinvertebrates and water quality in South West region of Cameroon
Authors: Chinche Sylvie Belengfe , Piscart Christophe , Mbanga Medjo Pascale , Koji Ernest , Tuekam Kayo Raoul Polycarpe , Zebaze Togouet Serge Hubert
Published: October 2023

We evaluated the impact of altitude on the biodiversity and water quality of 13 springs located from 82 to 1,189 m a.s.l. on Mount Cameroon. The springs were of good chemical and ecological quality whatever the altitude. The analysis of the physicochemical variables showed low temperature levels (19.50 ± 2.09 °C), high turbidity (13.0 ± 7.17 FTU), and an acceptable mineralization level (324.95 ± 260.0 μS/cm), with high amounts of phosphate nutrients (0.83 ± 0.47 mg/L). We observed a strong seasonal effect, with a decrease in temperature and nutrient content during the dry season whereas pH and dissolved oxygen increased. A total of 10,265 organisms, distributed into 56 families, were collected. They mostly included insects (47.8%), closely followed by Arachnida (34.8%). Only two stygobite taxa were recorded, namely Darwinulidae and Stenasellidae. Total diversity slightly decreased with altitude, especially during the dry season. Despite lower temperature and more oxygen at higher altitudes, diversity, including EPT did not increase. Therefore, African fauna are less sensitive to rising temperature than the faunas of other areas of the world. This result may be explained either by the fact that African species are better adapted to warm, low-oxygen waters than species from other parts of the world, or by the absence of refuges in Mount Cameroon that are home to temperature-sensitive species. Consequently, the impact of climate change on aquatic macroinvertebrates in tropical Africa could be reduced.
Alliance: the sustainable regeneration of al-Azbakeya historical garden
Authors: Elhadidi May Loaay Mohamed
Published: October 2023

While the world is heading towards sustainability and climate action, Cairo is losing its greeneries. The project site lies in al-Azbakeya historical garden that lost more than 75% of its area to concrete structures, it is a part of historical Khedival Cairo that suffers from urban deterioration, high population, and pollution [1]. The project is a complex building that aims at converting al-Azbakeya garden into a hub of sustainable and green urbanism [2]. It also targets social and economic sustainability by tackling the problem of street vendors. The design approach is reached through site analysis to determine the challenges and opportunities of the site, and the project's targeted environmental, social, and economic impacts. Then, a functional program is established to integrate governmental and non-governmental organizations to provide collaborative sustainable solutions. The objectives are met by using four architectural design features: pixel-like interlocking masses, natural light, small buildings with local and recycled materials, and natural materials integrating with the garden context. Sustainable technologies are used in irrigation, energy use, and water use to ensure environmental sustainability [3]. Environmental analyses are developed to test the project's efficiency using Digital software plugins as Revit-Insight. Area Analysis is also carried out to check area distribution among different functions, while the Circulation Analysis shows best entrances and passages for pedestrians. The results are adding around 13 000 sqm (68% of total area) of green areas to the compact urban area, providing developed businesses in a regulated retail area for street vendors converting their problem into an asset supporting the Circular Economy Strategy, and reviving the livability of the community by cultural spaces like bookstores, open theater, and a second hand market promoting smart reuse. The project fulfills its objectives and meets the sustainable development goals 6, 7, 8, 11, 12, 13, 15, and 16.
Ätherische Öle als Hemmer des bakteriellen Quorum
Sensings
Authors: Melzig Matthias F.
Published: October 2023

Antibiotikaresistente Krankheitserreger stellen eine zunehmende Gefahr bei der
Behandlung von Infektionen dar. Insbesondere Biofilme als
Bakteriengemeinschaften rücken hier in den Fokus, da gegen sie
klassische Antibiotika zumeist wirkungslos sind. Eine wichtige Rolle bei der
Biofilmbildung spielt das Quorum Sensing, das durch ätherische
Öle gestört werden kann.
Handtherapie in der Rheumatologie – Dos and
Donʼts
Authors: Bitzer-Muñoz Susanne
Published: October 2023

Menschen mit einer Erkrankung aus dem rheumatischen Formenkreis zu behandeln ist
für Therapeut*innen eine Herausforderung, da sich die
Erscheinungsbilder individuell sehr unterschiedlich zeigen. Die Behandlung
erfordert viel Erfahrung und differenziertes Wissen über die
fortschreitenden Prozesse sowie die zahlreichen pathophysiologischen Mechanismen
der Erkrankung.
Optimal timing of simethicone administration prior to upper endoscopy: A multicenter, single-blind, randomized controlled trial
Authors: Beaufort I.N. , Verbeek R.E. , Bosman J.H. , Al-Toma A. , Bogte A. , Alvarez Herrero L. , Weusten B.L.A.M.
Published: October 2023

Background and study aims Simethicone is useful as premedication for upper endoscopy because of its antifoaming effects. We aimed to evaluate the effect of timing of simethicone administration on mucosal visibility.

Patients and methods In this multicenter, randomized, endoscopist-blinded study, patients scheduled for upper endoscopy were randomized to receive 40 mg simethicone at the following time points prior to the procedure: 20 to 30 minutes (early group), 0 to 10 minutes (late group) or 20 mg simethicone at both time points (split-dose group). Images were taken from nine predefined locations in the esophagus, stomach, and duodenum before endoscopic flushing. Each image was scored on mucosal visibility by three independent endoscopists on a 4-point scale (lower scores indicating better visibility), with adequate mucosal visibility defined as a score ≤ 2. Primary outcome was the percentage of patients with adequate total mucosal visibility (TMV), reached if all median subscores for each location were ≤ 2.

Results A total of 386 patients were included (early group: 132; late group: 128; split-dose group: 126). Percentages of adequate TMV were 55%, 42%, and 61% in the early, late, and split-dose group, respectively (P < 0.01). Adequate TMV was significantly higher in the split-dose group compared to the late group (P < 0.01), but not compared to the early group (P = 0.29). Differences between groups were largest in the stomach, where percentages of adequate mucosal visibility were higher in the early (68% vs 53%, P = 0.03) and split-dose group (69% vs 53%, P = 0.02) compared to the late group.

Conclusions Mucosal visibility can be optimized with early simethicone administration, either as a single administration or in a split-dose regimen.
Body Weight Satisfaction, Comments, Nutrition and Injury Risk in 489
Adolescent Elite Athletes
Authors: Fridén Cecilia , Ekenros Linda , Hirschberg Angelica Lindén , von Rosen Philip
Published: October 2023

Exposure to critical body weight comments in youth athletes could lead to
decreased self-esteem, affect body image, and increase the risk of eating
disorders and cause depressive symptoms. The aim was to explore differences
between sex, body mass index, sports type, with regards to body weight
satisfaction, exposure to critical body weight comments from their coach and
nutrition status in adolescent elite athletes. A questionnaire about body
weight, critical body weight comments and nutrition was distributed to 489
adolescent elite athletes and injury prevalence was monitored across 20 weeks.
The results showed that almost one in four athletes (n=116, 24%)
was not satisfied with their weight and 12% (n=59) had received
critical body weight comments from their coach. Of the athletes who were
unsatisfied with their body weight (n=116), 47% wanted to lose
weight (n=55). A significant (p<0.05) higher proportion of ice
hockey players and swimmers used nutritional supplements, were unsatisfied with
their body weight, and were more exposed to critical body weight comments
compared to athletes from other sports. Adolescent elite athletes as young as
15–16 years old are exposed to critical body weight comments from their
coach and experience challenges with body weight satisfaction that is partly
dependent on the sport-specific context.
Recovery Process for Sports-Related Concussion Assessed with Precise
Ocular Motility
Authors: Onodera Hidetaka , Mogamiya Takuma , Yatabe Kanaka , Fujiya Hiroto , Murata Hidetoshi
Published: October 2023

Ocular motility has been linked to Sports Concussion Assessment Tool 5 scores.
However, the link between ocular motility changes and assessment result changes
remains unclear. Hence, we investigated that potential link in patients with
sports-related concussions. We retrospectively included participants aged≥18
years who were diagnosed with a sports-related concussion. They underwent smooth
pursuit eye movement assessment for allocation to the good improvement (rate of
fundamental frequency≥15%) or minor improvement (<15%) groups. Sports
Concussion Assessment Tool 5 scores were determined at baseline and two weeks
later, and score changes were compared between the groups. Thirteen men
(mean±standard deviation age: 20.6±5.0 years) were included: eight (19.0±4.5
years) in the good improvement group and five (20.6±5.7 years) in the minor
improvement group. Symptom number (median=2.0 vs. 0.0), symptom severity
(median=22.0 vs. 3.0), single-leg stance (median=4.0 vs. 0.5), tandem stance
(median=1.0 vs. 0.0), and total errors (median=5.0 vs. 0.5) were worse (all
p<0.05) in the minor improvement group. Smooth pursuit eye movement
improvements measured using eye-tracking technology was linked to symptom
recovery in patients with sports-related concussions. Therefore, ocular motility
may be an objective indicator of sports-related concussions. Future studies with
more patients are needed to confirm these findings.
Psychometric Evaluation of the Misophonia Impact Questionnaire using a Clinical Population of Patients Seeking Help for Tinnitus, Hyperacusis, and/or Misophonia
Authors: Aazh Hashir , Moore Brian C.J. , Scaglione Tricia , Remmert Nico
Published: October 2023

Background Misophonia is a decreased tolerance of certain sounds related to eating noises, lip smacking, sniffing, breathing, clicking sounds, and tapping. While several validated self-report misophonia questionnaires exist, none focus solely on the impact of misophonia on the patient's life. Additionally, there are no available validated pediatric self-report measures of misophonia. Therefore, a tool was needed to assess the impact of misophonia on both adult and pediatric patients.

Purpose To evaluate the psychometric properties of the 8-item Misophonia Impact Questionnaire (MIQ).

Research Design This was a retrospective cross-sectional study.

Study Sample Patients who attended the Tinnitus and Hyperacusis Therapy Specialist Clinic in the United Kingdom seeking help for tinnitus, hyperacusis, and/or misophonia (n = 256). A subsample of children aged 16 years or younger (n = 15) was included for preliminary analyses of a version of the MIQ to be filled in by a parent (MIQ-P).

Data Collection and Analysis Data were collected retrospectively from the records of patients held at the audiology department. These included demographic data, audiological measures, and self-report questionnaires taken as part of routine care. Descriptive statistics and psychometric analyses were conducted. The MIQ was analyzed for item difficulty, factor structure, reliability, and construct validity.

Results Confirmatory factor analysis revealed that a one-factor model for the MIQ gave an excellent fit and its estimated reliability was excellent, with Cronbach's α = 0.94. The total MIQ scores were highly correlated with scores for the Hyperacusis Impact Questionnaire and Sound Sensitivity Symptoms Questionnaire. MIQ scores were not significantly correlated with scores for the Tinnitus Impact Questionnaire or average hearing thresholds. Preliminary data from the subsample indicated excellent internal consistency for the MIQ-P, with Cronbach's α = 0.92.

Conclusions The MIQ is a promising questionnaire for assessing the impact of misophonia. Future studies should focus on establishing test/retest reliability, identifying clinically significant change in MIQ scores, defining the severity of misophonia impact categories, and further exploring the psychometric properties of the MIQ-P.
Proton Therapy for Skull Base Chondrosarcoma
Authors: Tang Dennis M. , Cutri Raffaello M. , Wu Arthur W. , Patil Chirag , Zumsteg Zachary S.
Published: October 2023

Chondrosarcoma is a type of an endochondral bone malignancy that is primarily treated surgically with radiation therapy used in the adjuvant setting or in cases of unresectable disease. Proton therapy has potential advantages compared with traditional photon therapy for the treatment of tumors in close proximity to critical structures due to the theoretic lower exit dose. Studies have shown improved survival in patients with skull base chondrosarcoma who undergo proton therapy. However, there is a lack of randomized data. Further studies are needed to define the role of proton therapy in the treatment of skull base chondrosarcoma.
Chiral Cyclodimerization Reactions: Construction of Nonnatural Dimeric Carbazoles from (±)-4-Methylene-3-hydroxytetrahydrocarbazoles
Authors: Baire Beeraiah , Mishra Surabhi , Roy Debayan
Published: October 2023

In this Synpacts article, we describe the concept of cyclodimerization in the biosynthesis and biomimetic synthesis of natural products and unnatural products. We also discuss key details of our discovery and development of a biomimetic-like, selective, homo- and heterochiral cyclodimerization strategy for the construction of nonnatural dimeric carbazole frameworks by employing a formal [3+2] annulation. Our work also demonstrated a novel reactivity of 1-(indol-2-yl)pent-4-yn-3-ols, and their potential as new synthetic building blocks in organic synthesis.

1 Introduction: Chiral Cyclodimerization Reactions

2 Biomimetic Syntheses of Natural Products through Chiral Cyclodimerizations

3 Bioinspired Synthesis of Nonnatural Dimeric Carbazoles through Selective Chiral Cyclodimerizations

4 Future Perspectives and Conclusions
Activation of Stable and Recyclable Phenylpropiolate Glycoside (PPG) Donors by Iron Catalysis
Authors: Kumar Amit , Aghi Anjali , Mishra Saksham
Published: October 2023

The glycosylation reaction is one of the important aspects of carbohydrate chemistry, where two different units are frequently linked through C–O bonds. In the pursuit of advancing this field, the design and development of sustainable catalytic methods for O-glycosylation, which can provide an alternate and effective tool to traditional protocols involving stoichiometric promoters and classical donors, are considered as highly challenging, yet important facets of glycochemistry. Herein, we report a simple and efficient Fe(III)-catalyzed method for O-glycosylation through the activation of bifunctional phenylpropiolate glycoside (PPG) donors. This mild and effective method involves the use of the inexpensive and less toxic FeCl3 as catalyst and easily synthesizable, benchtop-stable glycosyl ester-based PPG donors, which react with various sugar as well as non-sugar-based acceptors to deliver the corresponding O-glycosides in good yields with moderate anomeric selectivity, along with regeneration of easily separable phenylpropiolic acid. Importantly, d-mannose and l-rhamnose-based PPG donors afforded the corresponding O-glycosides in high α-anomeric selectivity. The reaction conditions were further explored for the synthesis of trisaccharides.
Benzoxazole or Benzothiazole as an Innate Directing Group for Palladium- and Ruthenium-Catalyzed Complementary C–H Arylation: Functionalization of Biorelevant Heterocyclic Scaffolds
Authors: Seth Kapileswar , Maingle Mohit , Sunny Steeva , Sheeba Loddipalle , Pathan Firojkhan Rajekhan
Published: October 2023

The benzoxazole and benzothiazole moieties were used as innate directing groups for Pd(II)- and Ru(II)-catalyzed C–H arylation of the biorelevant heterocycles 2-arylbenzoxazole and 2-arylbenzothiazole with diverse iodoarenes; palladium and ruthenium catalysis could be used complementarily. The use of σ-donor ligands, such as N,N-dimethylacetamide in the Pd(II) catalytic cycle, and σ-donor/π-acceptor ligands, such as PPh3 in the Ru(II) catalytic cycle, enhanced the arylation rate significantly and was governed by the C–H acidity of the C2-aryl ring of the 2-arylbenzoxazole or 2-arylbenzothiazole. These approaches have a broad substrate scope with respect to coupling partners, to accommodate electron-neutral, electron-rich, as well as electron-deficient iodoarenes; the C2-aryl unit of the 2-arylbenzoxazole or 2-arylbenzothiazole exhibited a high degree of site selectivity at the ortho C–H position, affording only monoarylated derivatives in decent yields; the reactions are functional-group-tolerant and applicable to gram-scale production.
Recent Progress in Developing Thioether-Containing Ligands for Catalysis Applications
Authors: Bellemin-Laponnaz Stéphane , Achard Thierry
Published: October 2023

The ligand that stabilizes the metal center is crucial to its catalytic activity. Historically dominated by phosphorus and nitrogen, sulfur has long been little considered as a hetero element for stabilizing a potentially active metal center. However, this situation is changing and we are seeing more and more examples that incorporate this element. This review provides an overview of recent transition-metal-catalyzed reactions with ligands containing neutral sulfur groups, i.e. thioethers. A selection of examples published since 2013 illustrates the diversity of applications of thioether-containing ligands and shows that sulfur should be more widely used in the development of homogeneous catalysis.

1 Introduction

2 Phosphorus-Thioether Ligands

3 Nitrogen-Thioether Ligands

4 Oxygen-Thioether Ligands

5 NHC-Thioether Ligands

6 Cycloolefin-Thioether Ligands

7 Conclusion
Diastereoselective Synthesis of Carbohydrate Conjugates: Pyrano[3,2-c]quinolones
Authors: Singh Brajendra K. , Kumar Sumit , Arora Aditi , Kumar Sandeep , Kumari Priti , Singh Sunil K.
Published: October 2023

A facile and efficient protocol for the diastereoselective synthesis of pyrano[3,2-c]quinolone carbohydrate derivatives from Perlin aldehydes and 4-hydroxyquinolones has been developed using a one-pot condensation at room temperature. In this investigation, glucose and galactose were employed as inexpensive starting materials to synthesize two sets of pyrano[3,2-c]quinolone-based carbohydrate conjugates. A total of sixteen novel compounds were successfully synthesized using this methodology in good to excellent yields. The reaction exhibited remarkable diastereoselectivity, resulting in a single diastereomeric product with a diastereomeric excess (dr) 97:3 for glucose, while a diastereomeric mixture with a diastereomeric excess (dr) 67:33 was obtained for galactose. The structural characterization of all sixteen compounds was carried out using various analytical techniques, including IR, 1H NMR, 13C NMR, 1H-1H COSY, 1H-13C HETCOR experiments, 2D NOESY NMR, and HRMS data. Additionally, the scalability of the protocol was successfully demonstrated by synthesizing one of the compounds on a gram scale, highlighting its potential for large-scale production.
Pediatric Acquired Demyelinating Syndrome (ADS)—A Proposed Flowchart for Imaging Diagnosis
Authors: Jeswani Sakshi , Senthilvelan Santhakumar , Ratnaparkhi Chetana , Umredkar Ashwini , Pande Shilpa
Published: October 2023

Pediatric acquired demyelinating syndromes (ADS) consists of a group of neuroinflammatory disorders, which include monophasic acute disseminated encephalomyelitis, multiple sclerosis, aquaporin-4 antibody-associated neuromyelitis optica spectrum disorder, myelin oligodendrocyte glycoprotein antibody-associated disease, and seronegative ADS. Various advances have been made in understanding their pathology, clinical, and imaging features for providing timely and precise diagnosis to ensure appropriate patient management. Imaging serves as an important tool in not only for diagnosis of demyelination but also helps in distinguishing them. In this case series, the authors have tried to assess distinctive imaging features of these disorders and arrive at an algorithmic approach for the diagnosis of various pediatric demyelinating disorders.
A Randomized Trial of Three Homeopathic Drugs: Rauwolfia serpentina, Viscum album, and Spartium scoparium in Essential Hypertension
Authors: Mandal Dibyendu , Maity Soumyadeep , Shaikh Abdur Rahaman , Ahamed Sabir , Ghosh Priyanka , Mukherjee Shyamal Kumar , Koley Munmun , Saha Subhranil
Published: October 2023

Hypertension (HTN) remains one of the major risk factors for heart failure, stroke, and coronary heart disease worldwide. This study was undertaken to compare the antihypertensive effects produced by the mother tinctures (MTs) of three homeopathic drugs—Rauwolfia serpentina (RS), Viscum album (VA), and Spartium scoparium (SS; also known as Cytisus scoparius [CS]) in essential hypertension. This open-label, randomized, three parallel arm, pragmatic, pilot trial was conducted on 60 participants with essential hypertension in the outpatient department of D. N. De Homoeopathic Medical College and Hospital, Kolkata. Participants were randomized into three groups: RS, VA, and SS equally. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at baseline and after 30 and 60 minutes. Group differences at different time points and overall were measured using one-way analysis of variance (ANOVA) and three-way repeated measure ANOVA models, respectively, after adjusting for baseline differences using intention-to-treat approaches. A p value less than 0.05 was considered statistically significant. Endpoint analysis included 60 participants. Although the highest mean reductions in SBP and DBP with time were achieved in the RS group, all three medicines revealed similar antihypertensive effects without any significant differences (SBP: F
2, 57 = 1.710, p = 0.190; DBP: F
2, 57 = 0.732, p = 0.485). No harm or serious adverse events were reported from either of the groups. All three medicines (RS, VA, and SS) produced similar antihypertensive effects in essential hypertension.

Trial registration: CTRI/2021/02/031548; UTN: U1111–1264–6856.