bluuebunny/crossref_metadata_2025 huggingface dataset:
Ентеропанкреатичний синдром і його вплив на трофологічні порушення при хронічному панкреатиті
Authors: Babinets L.S. , Kotsaba Yu.Ya. , Denefil O.V.
Published: January 2022

При дослідженні мікрофлори товстого кишечника у хворих на хронічний панкреатит у 72 % випадків був знайдений дисбіоз різного ступеня вираженості. Було виявлено, що дисбіотичні зміни спричинюють збільшення загального рівня білка крові, м’язової маси плечей та індексу маси тіла. Вони також призведуть до формування й збільшення вторинної імунної недостатності внаслідок підвищення кількості Т- і В-лімфоцитів. Був виявлений вірогідний прогностичний вплив мікрофлори товстого кишечника у хворих із хронічним панкреатитом на формування й прогресування анемії на підставі вірогідної кореляції між рівнями гемоглобіну й еритроцитів крові та кількістю лакто- і біфідобактерій (R у межах 0,3–0,6), а також умовно-патогенних організмів і загальної кількості E.coli (R у межах (–0,3) — (–0,6)).
Функціональний стан шлунка та імунологічна резистентність у дітей перших місяців життя
Authors: Dmytriieva S.M.
Published: January 2022

У статті подано результати дослідження функціонального стану шлунка, показників неспецифічної резистентності та мікробної колонізації кишечника в новонароджених та дітей перших місяців життя. Встановлено, що в перші місяці життя віковою особливістю є слабокислий інтрагастральний рН (4,6 ± 0,5). Цикл міжтравної моторики визначається режимом годування малюків. При повній евакуації шлункового вмісту через 2,5–3,0 години після годування дитини моторика шлункових скорочень становить (5,4 ± 0,4), внутрішньошлунковий тиск — (13,1 ± 1,3) мм рт.ст. Показано, що функціональне становлення шлунково-кишкового тракту здійснюється у взаємозв’язку з процесами формування місцевих факторів неспецифічного захисту травної системи та фізіологічної контамінації кишечника.
The role of bile acids in morphological changes оf gastric mucosa in rats
Authors: Rudenko A.I. , Mosiychuk L.M. , Oshmyanska N.Y.
Published: January 2022

The present study was conducted on 60 white male laboratory rats in order to investigate the role of bile acids in morphofunctional changes of gastric mucosa in rats with due regard to exposure of bile and its concentration. It was found that in the early stages of duodenogastric reflux in experiment bile in low concentrations carries protective adaptive-trophic function and promotes cell renewal of the surface epithelium. At the same time long-term exposure to the bile acids regardless of its concentration can lead to the significant dystrophic changes in gastric mucosa, pilorization and atrophy of the gastric glands. In the case of the oral administration of bile followed by «immobilization and cold stress» for one hour (I group) experiment’s results can confirm that the combined effects of several aggressive factors lead to the more severe pathological changes in the gastric mucosa: first erosive and later ulcerative lesions.
Гепатологические аспекты метаболического синдрома и возможности патогенетического лечения
Authors: Cherniavskyi V.V. , Sizenko A.K.
Published: January 2022

Статья посвящена проблеме метаболического синдрома и развитию печеночной недостаточности у пациентов с этой патологией. Приводятся данные, свидетельствующие о целесообразности назначения таким пациентам препарата комплексного действия — орнитина аспартата (оригинальный орнитина аспартат Гепа-Мерц производства «Мерц Фарма ГмбХ и Ко»). Эффективность Гепа-Мерца проявляется уменьшением цитолиза гепатоцитов, нормализацией липидного и углеводного обмена, а также положительным влиянием на клинические проявления печеночной энцефалопатии.
Тактика и хирургическое лечение механической желтухи различной этиологии
Authors: Ratchik V.M. , Prolom N.V. , Orlovskyi D.V. , Burenko A.N.
Published: January 2022

В отделении хирургии органов пищеварения ГУ «Институт гастроэнтерологии НАМН Украины» за период с 2003 по 2013 г. оперировано 567 пациентов с патологией гепатопанкреатобилиарной зоны различной этиологии, осложненной механической желтухой. Двухэтапному лечению подлежали 197 (34,7 %) больных с билирубинемией более 200 мкмоль/л и III степенью печеночной недостаточности. Эндоскопические (двухмоментные) методики применялись при лечении 143 (25,2 %) пациентов с холедохолитиазом. Одномоментные мини-инвазивные вмешательства — лапароскопическая холецистэктомия, наружное дренирование холедоха, литэкстракция, баллонная дилатация сфинктера Одди — выполнены у 41 (10,4 %) пациента. При осложненном хроническом панкреатите дренирующие оперативные вмешательства проводились у 20 (25,6 %) пациентов и резекционно-дренирующие — у 39 (50,0 %), с коррекцией желчеоттока, а также осуществлялись эндоскопические, лапароскопические и мини-инвазивные пункционно-дренирующие операции. 2 (2,6 %) больным выполнена панкреатодуоденальная резекция по Whipple. Двухэтапные оперативные вмешательства были выполнены 26 (33,3 %) пациентам. При опухолях холангиопанкреатодуоденальной зоны у 18 (30,5 %) больных провели чрескожные эндобилиарные разгрузочные вмешательства с последующим радикальным хирургическим лечением 10 (16,9 %) пациентов.
Death and regeneration of the pancreatic islets in relation to the development of fibrosis in patients with chronic pancreatitis
Authors: OSHMYANSKA N.Y.
Published: January 2022

The present study was conducted on biopsy material obtained from 65 patients with complicated chronic pancreatitis and 6 samples of tissue from intact pancreas. Сellular composition, islets’ death and regeneration were analyzed using histological and immunohistochemical methods depending on the fibrous transformation in the development of chronic pancreatitis. Given study provides a detailed description of the histological changes that occur in the pancreas during the development of fibrosis, along with expression patterns of pro-apoptotic nucleases Endonuclease G and DNase, and the proliferation markers PCNA and Neurogenin-3 at different stages of chronic pancreatitis.
Значення фекального кальпротектину при ротавірусній інфекції в дітей раннього віку
Authors: Abaturov O.Ye. , Stepanova Yu.Yu.
Published: January 2022

У статті подані результати дослідження, що характеризують рівень кальпротектину в калі в дітей раннього віку з ротавірусною інфекцією. Метою даного дослідження було визначення значення флуктуацій концентрації фекального кальпротектину при ротавірусній інфекції в дітей. Обстежено 105 дітей раннього віку, у яких був діагностований ротавірусний гастроентерит. Показана динаміка зміни вмісту кальпротектину в калі в дітей із ротавірусною інфекцією. Встановлено відсутність залежності концентрації кальпротектину в калі від тяжкості перебігу ротавирусного ентериту. Показано обернено пропорційний зв’язок між наявністю дисахаридазної недостатності та рівнем кальпротектину в калі в гострий період ротавірусної інфекції в дітей.
Стеатоз печени и стеатогепатит — неизбежность смешанного генеза
Authors: Stepanov Yu.M.
Published: January 2022

Представлен анализ этиологических и патогенетических механизмов формирования стеатоза и стеатогепатита смешанного генеза. Показано, что одним из основных этиопатогенетических факторов развития стеатоза печени и стеатогепатита остается алкоголь, роль которого прослеживается у 46–65 % пациентов. Накоплены убедительные данные, свидетельствующие о том, что ожирение, инсулинорезистентность представляют собой факторы прогрессирования стеатоза и стеатогепатита алкогольной, неалкогольной и смешанной этиологии. Одновременное влияние нескольких этиологических факторов приводит к незамедлительному развитию стеатоза и стеатогепатита у 95 % пациентов. Многие триггерные факторы можно рассматривать как взаимодополняющие факторы поражения печени смешанного генеза. Приведены общие подходы к диагностике, лечению, представлены основные группы лекарственных препаратов для коррекции стеатоза и стеатогепатита смешанного генеза.
Landslide Risk Analysis in Kelud Volcano, East Java, Indonesia
Authors: Bachri Syamsul , Sumarmi Sumarmi , Utaya Sugeng , Irawan Listyo Yudha , Wahyu Ning Tyas Lela , Dwitri Nurdiansyah Farizki , Erfika Nurjanah Alif , Wirawan Rahmat , Amri adillah Akhmad , Setia Purnama Denny
Published: January 2022

Pandansari village became one of the villages that has frequent landslide events in the period 2009-2015 compared with the surrounding area in Malang regency. The purpose of this study was to determine the level of landslide risk located within an active volcano. To enhance the comprehensive analysis of landslide disasters, we used a risk concept in this study. The landslide risk analysis was based on 3 determinants, namely hazards, community vulnerability, and regional capacity. The data collections were conducted using observation and documentation for landslide hazards and interviews as well as  Focus Group Discussion (FGD) for vulnerability and capacity aspects. The interviewed were applied for community and local government of Pandansari village. The recorded interviews were transcribed and analyzed according to recurrent themes in the answers. Findings from field investigation were then confronted with previous existing concepts of human exposure to natural hazards. Furthermore, the landslide hazard data were analyzed using spatial analysis tools, including GIS scoring, weighting, and overlaying weighted sum. The results showed the level of landslide risk has different values depending on the risk parameter, community vulnerability, and regional capacity. The level of landslide risk was divided into three levels, namely high with an area of 557.71 ha, moderate with 774.49 ha, and low with 1118.77 ha. Each of the risk factors, vulnerability, and capacity, has its characteristics in influencing the landslide risk in Pandansari Village. In relation to landslide disaster management, the risk analysis gives comprehensive input reaching good management practice in Pandansari village.
River Flow Modelling for Sustainable Operation Of Hydroelectric Power Plant in the Taludaa-Gorontalo Watershed
Authors: Salim Sardi , Polin Muchlis
Published: January 2022

River flow discharge is generally measured by multiplying the cross-sectional river area at the measurement point with the flow velocity. However, this approach cannot be used for planning needs which involves knowing the changes in discharge values at all times, which are directly affected by the variations in weather conditions and catchment area systems. This is necessary because planning errors usually lead to unsustainable and interrupted operations. It is possible to determine the changes in the river discharge values using the rainfall-runoff modelling technique through the hydrograph output of the model. Therefore, this study used hydrological modelling techniques to obtain a watershed's spatial and temporal river flow discharge. This involved using parameters such as watershed area, curve number representing land use and soil type, time lag as the delay between maximum rainfall and the occurrence of peak discharge, and the initial abstraction that considers all the losses before the runoff occurred. Moreover, rainfall data were obtained from an ARR station installed around the watershed area, while water level data were retrieved through an AWLR station installed in the river at the debit measurement point. The model was analyzed using HEC-HMS software, while the dependable discharge for power plants was analyzed using the flow duration curve method. The results showed that the rainfall-runoff hydrological modelling technique applied to the Taludaa-Gorontalo sub-watershed could ensure the continuous and sustainable operation of the hydroelectric power plant.
Unregistered artesian Well Management in Pasuruan, Indonesia: An Attempt to Protect Groundwater Resources
Authors: Hendrayana Heru , Riyanto Indra Agus , Nuha Azmin , Lisan Ahmad Rif’an Khoirul
Published: January 2022

The number of unregistered artesian wells increases every year in the northern slopes of Bromo Volcano, Pasuruan. Artesian wells are used for domestic needs and agricultural irrigation but are not followed by environmentally sound groundwater use. The purpose of this study is to assess the potential for groundwater, groundwater use, wasted groundwater, and recommendations for groundwater management.  The groundwater potential was obtained by measuring the depth of the groundwater table, piezometric surface of artesian wells, and geoelectrical data. Water uses were obtained from calculations based on the Indonesian National Standard. The amount of wasted groundwater was obtained by comparing the groundwater potentials, groundwater uses, and groundwater discharges from unregistered artesian wells. Water transfer was assessed by selecting unregistered artesian wells with discharges able to fulfill the water demands of each village. Groundwater in the Sub-Districts of Gondang Wetan and Winongan has high potential consisting of 1 unconfined aquifer group and two confined aquifer groups. Gondang Wetan and Winongan Sub-Districts are characterized as wasting groundwater potential through unregistered artesian wells. The discharge flow of unregistered artesian wells exceeds the water needs (>100%) in Winongan and Gondang Wetan Sub-Districts. Groundwater can be managed by water transfer, closure of artesian wells, and regulation of artesian wells use. Water can be transferred to areas not covered by Artesian wells in 20 villages. The number of artesian wells used for water transfer is 20 with a discharge of 5-20 liters/s.
MANIFESTASI IDENTITAS ISLAM SUKU BAJO DALAM NASKAH LONTARAK ASSALENNA BAJO
Authors: Baskara Benny
Published: January 2022

The Bajo people are known as the sea wanderers because they always wander the sea. However, aside from their unique characteristic as people of the sea, the Bajo are also known as Muslims. Therefore, Islam is an important element of their identity, either reflected in their daily life or written in the manuscript Lontarak Assalenna Bajo as the form of self-narration of their cultural history. Islam has been accepted through a continual process of negotiation and development.The Bajo people were not Muslim before they became sea wanderes. They received the influence of Islam from the land-bound people surrounding them as a result of interactions between the two groups.
DISKURSUS “ILLEGITIMATE SEXUAL ACTIVITY” ANAK BANGSA DALAM PERSPEKTIF TABLOID INDONESIA
Authors: Kurnia I Nisa
Published: January 2022

y “masculine-heterosexual”language, which in this context language is defined absolutely by the state. This paper is intended to dismantle the usage of "masculine-heterosexual" language by the Indonesian mass media when defining and putting illegitimate sexual activity in the landscape of the nation's discourse regarding sexuality. Using critical multiculturalism framework, identity theory and constructivist paradigm, this paper will explore discourse articulated by mass media in articles regarding those matters. Using discourse analysis as the method, a corpus of four tabloids (Tabloid Nova No. 1165/XXIII 21-27 Juni 2010, Tabloid Bintang Edisi 997 Tahun XX Minggu Ketiga Juni 2010, Tabloid Wanita Indonesia No. 1069 21-27 Juni 2010, and Tabloid Genie Edisi 50 Tahun VI, 21-27 Juni 2010) are discussed..
PERTUMBUHAN MEGAURBAN KEDUNGSEPUR
Authors: Wilonoyudho Saratri
Published: January 2022

Over the last 20 years many urban areas have experienced dramatic growth, as a result of rapid population increase and the trans formation of the world economy because of a combination of  rapid technological and political change. In the case of Kedungsepur, the area has seen more than twofold growth. Migrants come to the inner zones from both the area's core and elsewhere in the country. Net migration, in many case, contributes as much as two thirds of the population growth in these zones, whereas in the city cores, net migration contributes little to growth. A comprehensive model suggests that urbanization in Kedungsepur is influenced by structural and social demographic factors. Thus, the balance between managing urban discharges to the environment and enhancing environmental resource capacity is the key determinant of sustainability.
CIVIC PLURALISM: KEMBALINYA OTORITAS KERAGAMAN SIPIL
Authors: Saputro Endy
Published: January 2022

Pluralisme merupakan strategi hidupbersama setelah konflik di suatu masyarakatterjadi. Sebagai sebuah strategi, menurutSartori (1997), pluralisme dikenal pertamakali sekitar abad ke-16 dan ke-17, setelahperang berbasis agama usai di daratan Eropa.Menarik di sini, bahwa konflik yang terjadijustru berkaitan dengan agama danbukan sekadar perang politik/fisik semata.Pluralisme dengan demikian tidaklah munculdari ruang agama an sich, yang dikreasikandi dalam sebuah agama; meskipun,istilah ini lahir di dalam masyarakatberagama yang intoleran.
REPRESENTASI WACANA GENDER DALAM UNGKAPAN BERBAHASA INDONESIA DAN BAHASA INGGRIS: ANALISIS WACANA KRITIS
Authors: Budiwati Tri Rina
Published: January 2022

The result depicts that based on intra-linguistic analysis, English, and Indonesian idioms which contain gender discourse are in the forms of noun, phrases, Sub-clause, Simple sentence, Elliptical sentence, Compound, Complex, and Compound-Complex sentences. Based on the meaning and reference analysis, it is known that such idioms have various meanings: strength and weaknesses, success, marriage, sexuality, negative things, and wisdom. Besides, seen from the doer, the idioms can refer to men, women, and men and/or women. Based on CriticalDiscourse Analysis (CDA), such idioms can be analyzed based on the aspects of action, context, history, power, ideology and representation, which, then, are known that: (a) men are assumed as representative in various affairs and things (esp. in success and goodness); (b) men are active in marriage and sexuality; (c) women take more part in domestic domain; (d) women become negative metaphor; and (e) there is unequal relationship between womenand men.
PARADOKSALITAS DI BALIK KEMEGAHAN BOROBUDUR
Authors: Suharto Bambang
Published: January 2022

This article aimes at exploring the destination organization management of Borobudur temple. The approach methodused in this writing is descriptive interpretative of organization behavior. The data was collected from literaturestudy, participated observation, and the discussions in the seminars. The research’s fi ndings show that the successof organizations managing Borobudur has been focused on the fulfi llment of legal and economic responsibilitiesrather than social ones, as mandated by the Ministry of State-Owned Enterprises in law Nomor 40 of 2007 andLaw Nomor 10 of 2009. Moreover, it is aggravated by the behavior of urban society, members of which all havetheir own interets. Finally, the local community will become more marginalized if the government does not takeany serious actions taken to empower them immediately.
TINJAUAN KOGNISI DESAIN PRODUK KEMASAN SEBAGAI UNSUR IDENTITAS BUDAYA POPULER ATAS PRODUK KEMASAN MAKANAN INDUSTRI KECIL MENENGAH (IKM)
Authors: Hidayat Moch. Junaidi
Published: January 2022

Packaging is a media for producer and costomer to communicate the message through informative communication.The problem of packaging design will appear by the time of delivering the message in the form of sign, that car be considered as the game of cognition aspect. The expression of packaging sign is not only in the form of visual (text, image, color and other graphic aspects) but also in, material up to the function of packaging as symbolization of cultural development of the packaging design.This paper is a preliminary research result trying to identify, describe and prove the phenomena of design relationship between customer and packaging its and its effect to packaging production by Medium – Small Scale Industry (IKM), at the same time as the conceptual idea to improve the design object of food packaging of MediumSmall Scale Industry (IKM) in East Java based on Media-Cultural Study. The position of Medium – Small Scale Industry (IKM) becomes interesting because of the typical value of production consumption process of Medium – Small Scale Industry (IKM) compared to the fabrication scale is becoming the leader of packaging in the market.
STUDI PERKEMBANGAN WILAYAH DAN DAYA DUKUNG LINGKUNGAN KEPARIWISATAAN DI WILAYAH YOGYAKARTA UTARA
Authors: Muhamad Muhamad
Published: January 2022

The growth of tourist regions often indicates a decline of the environmental carrying capacity, includingthe confl ict regarding the use of space and its carrying capacity. The uncontrolled spatial growth andresources use is the result of the increasingly development-oriented policy which cause damage toenvironmental functions. Consideration of the use of space and natural resources advantage is needed inorder to properly consider the issue of carrying capacity. Research is needed to defi ne the proper use oftraffi c signals in connection with the above problem; it is alsoimportant to analyze the region’s carryingcapacity, which can defi ne its maximum tolerance and fl exibility of capacity. The long-term purpose isto improve tourists’ satisfaction with the area. There are (2) two variables considered: (1) the regionalgrowth; (2) the ecological carrying capacity. The research sample consists of four villages in the Pakemregion (Kaliurang area) and Merapi Volcano National Park (TNGM), DIY.
GENDER JUSTICE AND CULTURAL DIMENSION OF RELIGION, A PROPOSAL TO APPLY THE PROPHETIC TRADITION (THE HADITH) IN PROMOTING GENDER JUSTICE AMONG INDONESIAN MUSLIMS
Authors: Kodir Faqihuddin Abdul
Published: January 2022

By arguing that religion as interpretative culture of people in their context, suggested by Clifford Geertz, this paper proposes an interpretation-oriented approach to the texts of the hadith of the Prophet Muhammad rather than a critical-deconstructive approach. The interpretation-oriented approach focuses on positive reading towards the hadith that advocates issues of gender justice; whether through selecting classical methods of interpretation or applying contemporary methods suggested by progressive Muslims. As this approach does not challenge the authority of the hadith, which is accepted culturally by majority of Muslims as second source after the Quran, cultural works for gender justice are assumed to be relatively more flexible and can be further maximized. By doing so, I argue that this cultural dimension of religion –accepting its sources and working on the field of interpreting them-should be considered in promoting gender justice among Indonesian Muslims.
RITUAL SEBAGAI MEDIA TRANSMISI KREATIVITAS SENI DI LERENG GUNUNG MERBABU
Authors: Fitriasari Rr. Paramitha Dyah
Published: January 2022

Tradition developed in a community should continue to be preserved from generations to generations.Efforts are being made one of which is the process of transmission or inheritance. Transmission can bedone in various ways, one of which is ritual. Rituals which are performed continuously and regularlycan be a good medium for the transmission process. The ritual process of artistic creativity that wasdeveloped by the community on the slopes of Mount Merbabu is an example. Art goes hand in handwith the ritual is one of the transmission mediums used to continue an existing tradition. This researchseeks to show how ritual can be a transmission medium of art, particularly on the slopes of Merbabu.
BUDAYA NASIONAL DI TENGAH PASAR: KONSTRUKSI, DEKONSTRUKSI, DAN REKONSTRUKSI
Authors: Setiawan Ikwan
Published: January 2022

In the Reformation period, the state regime still mobilizes traditional-ideal values as national culturewithout giving conceptual and operational explanations. In this article, I combine two approaches,cultural studies and postcolonial studies, for reading national culture as represented in some PresidentSoesilo Bambang Yudhoyono’s presidential speeches. I will analyze ideal-but-ambivalent constructionsof national culture in regime’s perspective as represented in those speeches, particularly, in the contextof continuous of national culture in regime’s perspective in those speeches, particularly, in the context ofthe government’s continuous mobilization of traditional meanings as the invisible power for Indonesianpeople, while, at the same time,placing emphasis on economic progress.Instead of a strategic culturalconstruction, national culture produces its own deconstruction and fails to be discursive formation.Further, I argue that the regime operates their governmentality by reconstructing newer nationalculture based on market economics as discursive constructions, which ideally can provide conceptualand material basis for state regime in conducting governance and for citizens in achieving welfare inneoliberal formation.
LANJUT USIA: ANTARA TUNTUTAN JAMINAN SOSIAL DAN PENGEMBANGAN PEMBERDAYAAN
Authors: Sriyanto Eko
Published: January 2022

Social service and social security for elderly in 2010 only covered 143.131 person (Direktorat PSLU,2010) from expectation to serve 2,4 million elderly, whether it is poor and neglected elderly (BPS, 2010).Government capacity to serve social service and social security is limited, so it needs a new strategyto keep the sustainability of elderly’s life. We must have alternative way to assist them to solve theirpsychosocial and physical vulnerability through empowerment scheme. The psychosocial vulnerabilityof elderly is vulnerability that comprise from economic, social and psychological aspects so that it needscomprehensive understanding to make a program for them. Empowering the elderly will create activitythat will be advantageous for them to use the leisure, create social relationship, decrease felt of loneliness,keep reciprocal relationships with their social environment, increase income, and build their capacity inboth health and skills. The development of a sense of empowerment must consider several aspecteds,including environmental characteristics, social-demographic structures, and cross-generational actors.Alternatives for empowerment programs include productive activities (care housing and non-carehousing) and social activities (volunteering).
AGAMA NELAYAN: ISLAM LOKAL DI TANAH MANDAR
Authors: Idaman Idaman
Published: January 2022

Persentuhan Islam dengan kebudayaan Mandar, dalam catatan Arifuddin Ismail, bermula ketika Islam masuk di wilayah tersebut pada awal abad XVII M atau abad X H, tepatnya 1610 M yang dibawa oleh saudagar Arab Muslim, Syaikh Abdurrahim Kamaluddin, bersama para mubalighdari Makassar. Sebelumnya, kehidupan tradisional suku bangsa Mandar masih dalam suasana hinduistik. Kehadiran Islam di tengah-tengah mereka membawa ajaran dan nilai baru. Pertemuan dua kebudayaan tersebut melahirkan akulturasi antara Islam dengan kebudayaan Mandar (tradisi lokal), yang kemudiaan membentuk suatu tatanan nilai tersendiri menjadi tradisi Islam lokal, seperti kebudayaan nelayan Pambusuang.
PENGEMBANGAN DESA WISATA BERBASIS PARTISIPASI MASYARAKAT LOKAL DI DESA WISATA JATILUWIH TABANAN, BALI
Authors: Dewi Made Heny Urmila
Published: January 2022

The development of rural tourism requires the participation of local communities in the entire developmentphases starting from the planning, implementation, and supervision. However, in reality, public participationis often completely overlooked. This study aims to examine the involvement of local communities in thedevelopment of rural tourism and formulate the model of tourism development which uphols the participationof local community. The study is conducted in rural tourism Jatiluwih, Tabanan Regency, Bali. The process ofcollecting data through the studi literature, in-depth interviews and non-participant observation. The analyticalmethod used is descriptive analysis. The result of the research indicates that the development of rural tourismin Jatiluwih still does not yet involve the local community. The role of government seems dominant, but whenreferring to the clean and sustainable governance approach, the role of the government is expected to becomea facilitator by providing bigger opportunity to take part as well as the bene􀃀ts from the development to thelocal community. It is required the political will of the government to reduce the dominant role in developingrural tourism, through opening wider space for the community to participate.
RELIGIOUS LEADER AND CHARISMATIC LEADERSHIP IN INDONESIA:THE ROLE OF KYAI IN PESANTREN IN JAVA
Authors: Siregar Ferry Muhammadsyah
Published: January 2022

This paper discusses on the role of the kyai in pesantren in Java. It addresses on the roles of religiousleader in pesantren. It applies Max Weber’s concept on religious leadership and charisma. It usesqualitative data for analysis of materials collected from observations and library research. This research􀃀nds that the structures and patterns of leadership and power of Kyai within pesantren are strong inwhich kyai is positioned as the main 􀃀gure. It can be seen on how a kyai build his strategic role as thenon-formal leader in society through intensive communication with the people. The charisma of a kyaialso gains people’s support, to some extents, caused by his moral stability and faith quality. This processat 􀃀rst starts from the nearest group around the pesantren and then spread out to distant places.
PRAKTIK TANGGUNG JAWAB SOSIAL PERUSAHAAN PT. BAKRIE SUMATRA PLANTATIONS(TBK.) UNIT JAMBI
Authors: Suwandi Suwandi
Published: January 2022

Companies all over the world have implemented corporate social responsibility. This research is aimed toanalyze factors affecting CSR practice by Bakrie SumatraPlantations Unit Jambi, a palm oil plantation company. The CSR practice was hypothesized to be in􀃁uenced by government regulation and corporate strategy. The primary data was collected through survey, interviews, focused group discussion, anddirect observation in the 􀃀eld. Meanwhile, the secondary data was gathered from various documents. The data was analyzed by using quantitative and qualitative approaches.The result shows that thegovernment regulation CSR has no impact on the CSR practice. On the reverse, the corporate commitment and strategy were the decisive factors in the successful of CSR practice. This research also found that the CSR practice has contributedto the improvement of people’s economic and social conditions. The prominent weakness is that the CSR policies and strategies were top-down and the participation of local people were limited. The other empirical 􀃀nding is that the nucleus-plasma partnership was able to implement the basic principles of CSR which were prevailing generally in different sector of businesses.
Peran Kepemimpinan dalam Sinergi antar Dinas di Pemerintahan Daerah: Studi Program Percepatan Peningkatan Status Kemajuan dan Kemandirian Desa di Provinsi Kalimantan Barat
Authors: Fatmawati Siti
Published: January 2022

The role of leadership has been seen critical in the success of achieving the goals of the organization. Leadership is manifested through the leaders’ competence and capabily. In this perspective, many see the value of transformational leadership in implementing the program for promoting independent village program. The role of transformational leaders has become a key factor in bringing regional progress. The West Kalimantan Province is an example of the critical role a transformational leader as manifested at least by a Governor of West Kalimantan in his role between different government agencies (SKPD) in the independent village program. Based on the case study of West Kalimantan, This research aims to examine the role of the leadership role of the Governor of West Kalimantan in the independent village program. The research used a qualitative approach with case studies. Data are collected through structured interviews and document review and field observations. Some of the informants involved were officials in the West Kalimantan Provincial Government. The results showed that the leadership role of the Governor of West Kalimantan has succeeded in increasing the status of an independent village. The success of the independent village program has become a top priority as stated in the Governor’s Decree. The Governor’s involvement in building synergies between SKPDs has shown a spirit of transformational leadership that can be demonstrated as an innovator, motivator, facilitator and mobilizer.
"Shirobako":The Representation of Passion and Creative Labor in Japanese Animation Industry
Authors: Sarjiati Upik
Published: January 2022

Common narratives of the industry include extensive working hours, minimal wages and uncertain conditions. However, there are many creative workers desire to work in anime industry mainly due to passion. The purpose of this research is to analyze the representation of passion and creative labor in Japanese animation industry. Shirobako series provides a case study describing an animated movie production process. Studies on visual and narrative of anime have been conducted; however the study on the production aspect is limited. This study aims to portray anime production complexities and creative labor dynamic. Using constructive approach by Stuart Hall, this study assesses passion on individual and collaborative levels. Based on the results, the passion of creative personnel was personally and subjectively defined. This drive triggers the capacity to acquire new knowledge and endure challenging situations. Furthermore, information sharing and commitment are important qualities of collaborative production. In general, the Shirobako series acknowledged a power relationship gap between production committee members and the creative workforce.
Serious Leisure:Menelisik Profesi Travel Influencer
Authors: Saepulloh Saepulloh , Kusworo Hendrie Adji , Fandeli Chafid
Published: January 2022

Seiring perjalanan pertumbuhan peran media digital, travel influencer menjadi sektor pariwisata yang semakin penting. Mereka merupakan orang yang berpengaruh dalam kegiatan promosi destinasi dan produk-produk wisata. Mengawali karirnya dari hobi pelesir dan membagikan cerita perjalananannya di media sosial Instagram, hobi pelesir dan cerita perjalanan tersebut menarik pengguna Instagram lain untuk menjadi pengikut travel influencer. Hal ini akhirnya menjadi sebuah karir yang cemerlang dengan model kerja yang dilakukan para travel influencer secara profesional sebagai bagian dari pekerjaan utamanya (serious leisure). Pekerjaan sebagai travel influencer penuh-waktu membuka peluang kerjasama bisnis dengan pihak ketiga (endorsement), sehingga mobilitas menjadi padat karena jadwal perjalanan. Peneliti menggunakan metode deskriptif kualitatif dengan pendekatan netnografi. Selain itu, penelitian ini berfokus pada model kerja dengan konsep serious leisure. Hasil dari penelitian ini adalah menjadi seorang travel influencer membutuhkan waktu yang cukup lama dan membutuhkan ketekunan dan kesabaran lebih. Selain itu, meningkatkan kemampuan diri menjadi sebuah kewajiban saat menjalani karir sebagai seorang travel influencer. Studi ini mengungkap enam kualitas yang menjadi karakter serious leisure yaitu: (1) ketekunan, (2) karir , (3) usaha serius, (4) etos unik, (5) identitas, (6) keuntungan jangka panjang menjadi komponen yang saling berkaitan di dalam menekuni karir sebagai seorang travel influencer. Hal ini perlu diterapkan agar karir sebagai seorang travel influencer tetap dapat bertahan di karir travel influencer walapun semakin banyak bermunculan travel influencer baru lainnya.
Multi-grade Teaching impact in Extended Classroom
Authors: Pradhan Suren
Published: January 2022

The study reveals that the teachers and students require extra time to work hard beside the actual normal classes. It provides significant implications with the professional support needed by the teachers while dealing with classes by a single teacher. There is a need for teachers to be very active, professionally trained to handle the students learning to bring the better result. Based on my study, suggestions have been made that might help our future educationists, teachers and parents. I also come across that parent’s involvement is vital in order to support the classroom with a single teacher handling the classes
Estrés laboral y desempeño laboral en Avicarnes de Venezuela, C.A.
Authors: Rojas Leal José Alberto , Arteaga Salazar María Elena
Published: January 2022

La investigación tuvo como propósito determinar la relación entre el estrés laboral y el desempeño laboral en la empresa Avicarnes de Venezuela, C.A., sustentada por Velázquez et al. (2008), Robbins y Judge (2013), Leal (2018), entre otros. La investigación fue descriptiva y correlacional, con un diseño no experimental, transeccional y de campo, en el cual se empleó como técnica de recolección de datos la encuesta, para la cual se crearon dos cuestionarios como instrumentos de tipo dicotómicos con respuestas cerradas. La validez fue de contenido mediante juicio de expertos y la confiabilidad se obtuvo mediante el método de Kuder Richarson. La técnica de análisis fue la estadística descriptiva, mediante Figuras de barra con la frecuencia relativa. Los resultados obtenidos basados en el coeficiente de correlación de Pearson con un 0,86 permitieron concluir que existe una relación fuerte y positiva entre las dos variables objeto de estudio dentro de la empresa, lo que manifiesta que los cambios que ocurren en la variable del estrés laboral afectan a la variable del desempeño laboral; por lo tanto, se recomendó mejorar el clima organizacional, distribuir las actividades operativas de acuerdo al manual de funciones, realizar pruebas constantes a los niveles de estrés, implementar un programa de motivación y por último, estudiar políticas que permitan otorgar mayor remuneración a empleados con un mejor desempeño.
THE THERAPEUTIC EFFECT OF PIPER LONGUM LINN. FRUITS IN TESTOSTERONE INDUCED POLYCYSTIC OVARIAN SYNDROME IN FEMALE WISTAR RATS
Authors: Pokale Swati Babasaheb
Published: January 2022

The regulation of polycystic ovarian syndrome (PCOS) is intricate but often disappointing. The intend of existing study is to investigate effects hydro alcoholic extract of Piper longum L. (HEPL) fruits in testosterone persuaded Polycystic ovarian syndrome. Female wistar arts were separated into 9 groups (n=6). Normal Control received Sesame oil as a vehicle control once daily. Testosterone (2mg/kg/s.c.) was administered for 31days to induce PCOS induction in all remained group. PCOS persuaded animals were given with Metformin (300mg/kg/oral route), Clomiphene citrate, (150mg/kg/oral), HEPL groups (200, 400 and 800 mg/kg), Combination group (Piper longum 800 mg/kg and Metformin 300mg/kg) and Combination group (Piper longum 800 mg/kg and Clomiphene citrate,150mg/kg) up to 59 days using vehicle as a Distilled water. Body weights, estrus cyclicity, biochemical, hormonal and histological orders were measured. Testosterone persuaded PCOS marked by uneven estrus cyclicity, enhanced triglycerides, cholesterol, LDL glycaemia, testosterone and LH (p< 0.05, 0.001) levels were analyzed. To study insulin resistance, Oral glucose tolerance test was performed. Multiple cysts had been observed with PCOS rats as compared with the control group. Also, HEPL established the estrus periodicity. These biochemical, hormonal and structural alterations were abridged by Piper longum L. Moreover, Piper longum significantly decreased Cystic follicles count, testosterone and LH (p
THE TREND IN THE USE OF LOCAL TRADITIONAL MEDICINE JAMU DURING COVID-19: A CROSS-SECTIONAL STUDY IN EAST NUSA TENGGARA PROVINCE, INDONESIA
Authors: Nurina Rr. Listyawati
Published: January 2022

The world is facing yet a global health and socio-economic crisis triggered by the Corona Virus Disease-2019 pandemic. In the midst of a health crisis due to the pandemic that has not yet ended, traditional medicine is an alternative that can be used by the community to maintain their immune system. Jamu is a local traditional medicine in Indonesia made from natural cultural heritage that has been passed down from generation to generation for health. The design of this research is an observational study with a cross-sectional design in which the use of traditional medicine jamu will be observed using a questionnaire. The total sample of this study was 150 respondents, accumulated from North Central Timor, South Central Timor, West Sumba, Sikka, Sabu Raijua, Rote Ndao, Kupang Regency, Kupang City, Flores Timor and Alor. The result of this study depicted a 600% rise in respondents in using jamu during the Corona Virus Disease-2019 pandemic. In conclusion, there is a significant difference p Value < α (0.014 < 0.05) between the use of jamu before the Corona Virus Disease-2019 pandemic (January – March 2020) and during the pandemic (April June 2020) among households in East Nusa Tenggara Province, Indonesia.
NANO PHYTOREMEDIATION FOR TEXTILE DYE DEGRADATION USING ABUTILON INDICUM SILVER NANOPARTICLES: PHOTO CATALYTIC ACTIVITIES
Authors: Varalakshmi B
Published: January 2022

Synthetic dyes are colouring agents mainly used in textile industries which generate a huge amount of wastewater in the process of dyeing. Different dyes used in textile industry usually have a synthetic origin and complex aromatic molecular structures which make them more stable and more difficult to be biodegraded and thus polluting the environment. To overcome the deleterious effects of such dyes, it is necessary to decolorize them. In the present study, fabric azo dyes were decolourized by silver nano particle isolated from plant Abutilon indicum. Production and characterization of silver nanoparticles synthesized from Abutilon indicum was analysed by UV-visible spectroscopy and Fourier transform infra-red spectroscopy. Photo catalytic degradation using Abutilon indicum synthesized silver nanoparticles showed significant dye degrading efficiency against azo dye. At the end of 24 hours, nanoparticles of Abutilon indicum showed 17.41% of degradation, followed by increased degradation of about 72%. at the end of 7th day of incubation. Results confirmed the complex, toxic azo dyes were degraded into simple, non-toxic compounds. In conclusion, Abutilon indicum synthesized silver nanoparticles can exhibit excellent photo catalytic activity against dye molecules and can be used in water purification systems and dye effluent treatment.
A RETROSPECTIVE OBSERVATIONAL STUDY OF COMPARISON OF HEMATOLOGICAL PARAMETERS ALONG WITH THE EFFECT OF CHEMOTHERAPY AND RADIOTHERAPY IN DIFFERENT STAGES OF BREAST CANCER
Authors: Kumutha T
Published: January 2022

Breast cancer is one of the top leading causes of death and most common malignancies among women all over the world. Chemotherapy and radiotherapy are the predominant treatment measures of cancer along with surgery. The current study aims to compare the hematological parameters in patients undergoing chemotherapy and radiotherapy in different stages of breast cancer. A decline in hematological parameters is most commonly seen trend in patients undergoing these treatments, which adversely influences the outcome of cancers. The study also evaluates the prevalence of thrombocytopenia, neutropenia and anemia in patients who received radiotherapy, chemotherapy and concurrent therapy. A total of 103 female breast cancer cases were collected in which 23 patients received radiotherapy, 44 patients received chemotherapy and 36 patients received concurrent therapy. The hematological parameters were found to be declined at different stages of cancer. The patients also showed decline in blood counts at each treatment, but all the parameters were declined in patients undergone concurrent therapy. Thus, this study helps to evaluate the requirement of complete blood count investigation before and during the therapy in order to assist the dosage adjustment and dietary modifications to minimize the risk of therapy related fatigue and infections and thus improving the efficacy of treatment outcome and health related quality of life of patients.
SYNTHESIS, CHARACTERIZATION, MOLECULAR DOCKING AND ANTIMICROBIAL EVALUATION OF AZO COUPLED – 3, 4- DIHYDROPYRIMIDINE-2(1H)-ONE DERIVATIVES
Authors: Selvinthanuja C
Published: January 2022

A series of 5-acetyl-4-[(4-substituted phenyl) diazinyl) phenyl]- 6-methyl-3, 4-dihydropyrimidine-2(1H)-one derivatives were synthesised via the coupling reaction between 4- substituted-3, 4- dihydropyrimidine-2(1H)-one and diazonium salt of p-nitro aniline. All the synthesised compounds were structurally elucidated by elemental analysis and IR, 1H NMR and Mass spectral techniques. Investigation of antibacterial and antifungal activity was done on titled compounds using disc diffusion method. Moderate inhibitory activity were displayed by compounds IIa, IId against bacterial strains such as Escherichia coli, Staphylococcus aureus and fungal strains Candida albicans, Aspergillus niger at a concentration range from 400-800µg/ml. Antimicrobial activity of the compounds may be due to the presence of electron donating substituent on phenyl ring attached at fourth position of dihydropyrimidinones. Molecular docking investigation of synthesised compounds performed with bacterial DNA gyrase B which showed that the compound IIa had the binding affinity of -8.3kcal/mol and the compound IId had the binding energy of -9.1 kcal/mol against fungal sterol-14α-demethylase which further supported the biological activity.
DEVELOPMENT OF NOVEL SUBSTITUTED INDOLE MOLECULES AS POTENTIAL NAV1.7 INHIBITORS
Authors: Sonvane Sameep
Published: January 2022

Pain is often defined as a single form of the nervous system for abnormal things in the human body. Neuropathic pain is a type of pain that is a consequence of nerve damage and usually, it is a chronic type. Sodium Channel 1.7 (Nav 1.7) is an upcoming target for neuropathic pain management. Several heterocyclic compounds are reported for potentials against neuropathic pain. 24 different heterocyclic derivatives from substituted indole class were synthesized and virtually analyzed against Nav 1.7 for inhibition potential. The developed substituted indole was confirmed via spectral analysis and showed excellent binding ability with Nav 1.7, which can be further explored for biological activity for the development of potential Nav 1.7 inhibitors with excellent activity against Neuropathic pain.
First-party and third-party food delivery apps, which is better in Indonesia?
Authors: Benhardy Kartika Aprilia , Ronadi Matthew
Published: January 2022

Indonesia is a nation with considerable GDP growth because of high household consumptions. One of the contributors to household consumption is eating out, which drives the growth of online ordered food in Indonesia. Ordering food online can be done through a website and via application of that restaurant (first-party) or through third-party food delivery apps. This research wants to investigate further what factors are considered by the consumer when choosing an online food delivery app and also deciding if consumers prefer to use first-party or third-party food delivery apps. The field of this research is limited to Pizza Delivery Apps, and Analytic Hierarchy Process (AHP) is used to determine which factors are the most considered by consumers when choosing an application. The respondents of this research are just five people who have used pizza delivery apps in the past few months, and a geometric mean calculated to analyze the results. The results show that Trustworthiness and E-Service Quality are the most considered factors by consumers when choosing a food delivery app. Consumers highly consider first party food delivery apps which are PHD and Domino’s Pizza become the choice of consumers because of higher Trustworthiness factors. Third-party food delivery apps, which are Go-Jek and Grab, were rated by consumers to have a lower trust factor compared to first-party apps. This research shows food delivery apps by a restaurant (first-party) has it is own advantage compared to third-party food delivery apps.