bluuebunny/crossref_metadata_2025 huggingface dataset:
Whole Genome Resequencing Identifies Single-Nucleotide Polymorphism Markers of Growth and Reproduction Traits in Zhedong and Zi Crossbred Geese
Authors: Liu Guojun , Guo Zhenhua , Zhao Xiuhua , Sun Jinyan , Yue Shan , Li Manyu , Chen Zhifeng , Ma Zhigang , Zhao Hui
Published: February 2023

The broodiness traits of domestic geese are a bottleneck that prevents the rapid development of the goose industry. To reduce the broodiness of the Zhedong goose and thus improve it, this study hybridized it with the Zi goose, which has almost no broody behavior. Genome resequencing was performed for the purebred Zhedong goose, as well as the F2 and F3 hybrids. The results showed that the F1 hybrids displayed significant heterosis in growth traits, and their body weight was significantly greater than those of the other groups. The F2 hybrids showed significant heterosis in egg-laying traits, and the number of eggs laid was significantly greater than those of the other groups. A total of 7,979,421 single-nucleotide polymorphisms (SNPs) were obtained, and three SNPs were screened. Molecular docking results showed that SNP11 located in the gene NUDT9 altered the structure and affinity of the binding pocket. The results suggested that SNP11 is an SNP related to goose broodiness. In the future, we will use the cage breeding method to sample the same half-sib families to accurately identify SNP markers of growth and reproductive traits.
CRISPR/Cas9-Mediated Mutation in XSP10 and SlSAMT Genes Impart Genetic Tolerance to Fusarium Wilt Disease of Tomato (Solanum lycopersicum L.)
Authors: Debbarma Johni , Saikia Banashree , Singha Dhanawantari , Das Debajit , Keot Ajay , Maharana Jitendra , Velmurugan Natarajan , Arunkumar Kallare , Reddy Palakolanu , Chikkaputtaiah Channakeshavaiah
Published: February 2023

Fusarium wilt is a major devastating fungal disease of tomato (Solanum lycopersicum L.) caused by Fusarium oxysporum f. sp. lycopersici (Fol) which reduces the yield and production. Xylem sap protein 10 (XSP10) and Salicylic acid methyl transferase (SlSAMT) are two putative negative regulatory genes associated with Fusarium wilt of tomato. Fusarium wilt tolerance in tomato can be developed by targeting these susceptible (S) genes. Due to its efficiency, high target specificity, and versatility, CRISPR/Cas9 has emerged as one of the most promising techniques for knocking out disease susceptibility genes in a variety of model and agricultural plants to increase tolerance/resistance to various plant diseases in recent years. Though alternative methods, like RNAi, have been attempted to knock down these two S genes in order to confer resistance in tomato against Fusarium wilt, there has been no report of employing the CRISPR/Cas9 system for this specific intent. In this study, we provide a comprehensive downstream analysis of the two S genes via CRISPR/Cas9-mediated editing of single (XSP10 and SlSAMT individually) and dual-gene (XSP10 and SlSAMT simultaneously). Prior to directly advancing on to the generation of stable lines, the editing efficacy of the sgRNA-Cas9 complex was first validated using single cell (protoplast) transformation. In the transient leaf disc assay, the dual-gene editing showed strong phenotypic tolerance to Fusarium wilt disease with INDEL mutations than single-gene editing. In stable genetic transformation of tomato at the GE1 generation, dual-gene CRISPR transformants of XSP10 and SlSAMT primarily exhibited INDEL mutations than single-gene-edited lines. The dual-gene CRISPR-edited lines (CRELs) of XSP10 and SlSAMT at GE1 generation conferred a strong phenotypic tolerance to Fusarium wilt disease compared to single-gene-edited lines. Taken together, the reverse genetic studies in transient and stable lines of tomato revealed that, XSP10 and SlSAMT function together as negative regulators in conferring genetic tolerance to Fusarium wilt disease.
The Influence of the DSM Spatial Resolution in Rockfall Simulation and Validation with In Situ Data
Authors: Kakavas Maria P. , Nikolakopoulos Konstantinos G. , Kyriou Aggeliki , Koukouvelas Ioannis
Published: February 2023

Remote sensing constitutes an advantageous tool towards the landslide/rockfall susceptibility mapping by incorporating optical satellite or radar data and photogrammetric data in Geographical Information System environment. A plethora of rockfall data can be derived by gigital surface models (DSMs). This article focuses on the effect of the spatial resolution of DSMs in rockfall investigations solely. DSMs with pixel size ranging from 5 cm to 90 m were taken into account for the study of three different rockfall events occurring in Western Greece, namely, at Moira, Myloi and Platiana settlements. Elevation profiles along the rockfall bodies were created from the diverse DSMs in GIS environment. Then, these profiles were implemented into the RocFall software for 2D rockfall simulations. The produced simulations were evaluated against their spatial resolution of DSMs and were confirmed with field observations and measurements. The ultimate scope of this paper is to conclude to the most appropriate DSM for rockfall simulations via RocFall software. It is observed that DSMs with high spatial resolution depicted a detailed and realistic topography, while DSMs with coarse/low resolution flattened the surface roughness. As rockfall simulations are linked to slope profile, this observation has an impact on RocFall outcomes. According to this study the most appropriate DSM, pertaining to this type of research, is the UAV, which produces the more accurate and realistic results. These results were assessed through the use of in situ measurements taken by the real rockfall events.
Estimation of Heterosis and the Combining Ability Effect for Yield and Its Attributes in Field Pea (Pisum sativum L.) Using PCA and GGE Biplots
Authors: Sharma Amit , Yadav Rajesh , Sheoran Ravika , Kaushik Deepak , Mohanta Tapan , Sharma Kartik , Yadav Alpa , Dhanda Parmdeep , Kaushik Prashant
Published: February 2023

Field pea (Pisum sativum L.) is a highly nutritious winter-season pulse crop. It is used as food, feed, and fodder and offers nutritional security to low-income people in developing countries. Different graphical approaches like Principal Component Analysis (PCA) and Genotype + Genotype × Environment (GGE) biplots were used along with the conventional line × tester to identify efficient parents, combining ability effects and distinct heterotic groups in field pea (Pisum sativum L.). The study used a line tester design (9 × 3) for seed yield and its associated traits. In the conventional analysis, lines Aman and HFP 715 and the tester GP02/1108, as well as crosses HFP 715 × GP02/1108, Aman × GP02/1108, and Pant P-243 × HFP 1426 showed the best GCA (General Combining Ability) and SCA (Specific Combining Ability) effects, respectively, for seed yield and its attributes. The σ2SCA > σ2GCA, and σ2D > σ2A in almost all the traits indicated control of non-additive gene effects. High manifestations of heterobeltiosis for seed yield were evidenced by the superiority of 24 out of 27 crosses over the better parent. The highest significant heterobeltiosis was observed in the cross HFP 715 × GP02/1108, followed by IPF 14-16 × GP02/1108, IPF 14-16 × HFP 1426, DDR-23 × HFP 1426, DDR-23 × GP02/1108, and Aman × GP02/1108 for yield and its attributes. The biplot techniques were used to analyze data and compare their results with conventional line × tester analysis. Overall, graphical analysis results were very similar to those of traditional analysis. Consequently, it can surely be assumed that these methods could be helpful in presenting data from field pea breeding experiments carried out with line × tester design.
Does Early Victimization of School Bullies Affect Core Self-Evaluations in Young Adulthood? A Moderated Mediation Model
Authors: Wang Lixia , Zhou Shuzhi , Xue Yukang , Li Qianqian , Cao Min , Gu Chuanhua
Published: February 2023

Early victimization is associated with a range of psychological adaptation problems in young adulthood, including core self-evaluations. However, little is known about the mechanisms underlying the association between early victimization and young adults’ core self-evaluations. This study examined the mediating role of negative cognitive processing bias and the moderating role of resilience in the relationship. A total of 972 college students were recruited to complete measures of early victimization, negative cognitive processing bias, resilience, and core self-evaluations. The results showed that early victimization significantly and negatively predicted the core self-evaluations in young adulthood. The negative association between early victimization and core self-evaluations was completely mediated by negative cognitive processing bias. Resilience moderated the relationship between early victimization and negative cognitive bias, and the relationship between negative cognitive processing bias and core self-evaluations. Resilience has both risk-buffering and risk-enhancing effects. In light of these results, in order to help victims maintain good mental health, we should intervene in individual cognitive factors. Notably, while resilience is a protective factor in most cases, the benefits of resilience should not be overstated. So, we should not only cultivate students’ resilience but also provide them with more support and resources and intervene in risk factors at the same time.
Competitor-Weighted Centrality and Small-World Clusters in Competition Networks on Firms’ Innovation Ambidexterity: Evidence from the Wind Energy Industry
Authors: Zhao Runbo , Zhang Huiying , Zhang Marina Yue , Qu Fei , Xu Yunlong
Published: February 2023

A firm’s embedding structures in a technology competition network can influence its propensity for innovation ambidexterity. Using PCT (patent cooperation treaty) patent data of wind energy companies between 2010 and 2019, we adopted social network analysis and fixed-effects panel negative binomial regression to examine the impacts of network structural features on firm innovation ambidexterity. The results show that competitor-weighted centrality contributes to a firm’s propensities for both incremental and radical green innovation. In contrast, a firm’s embeddedness in small-world clusters can moderate the effect of the firm’s competitor-weighted centrality positively on its incremental innovation but negatively on its radical innovation. The study makes three theoretical contributions. First, it enriches the understanding of how the competition network affects innovation ambidexterity. Second, it provides new insights into the relationship between competition network structures and technology innovation strategy. Finally, it contributes to bridging the research on the social embeddedness perspective and green innovation literature. The findings of this study have important implications for enterprises in the wind energy sector regarding how competitive relationships affect green technology innovation. The study underscores the importance of considering the competitiveness of a firm’s rivals and the embedded structural features when devising green innovation strategies.
Addressing Cognitive Function and Psychological Well-Being in Chronic Kidney Disease: A Systematic Review on the Use of Technology-Based Interventions
Authors: Marin Alexandra-Elena , Redolat Rosa , Gil-Gómez José-Antonio , Mesa-Gresa Patricia
Published: February 2023

Patients with chronic kidney disease (CKD) are at risk of both a gradual decline in cognitive function and an increase in psychological distress. This includes symptoms of anxiety, depression, and sleep disturbances, all of which are factors that have been associated with increased morbidity and mortality. In response, we are now seeing that interventions based on new digital technologies are increasingly used in order to optimize patients’ quality of life. Systematic research of the literature on electronic databases (MEDLINE/PubMed, Scopus, Web of Science, and PsycInfo/ProQuest) covering the period from 2012 to 2022 was conducted in order to methodically review the existing evidence regarding the implementation and effectiveness of technology-based interventions in the management of cognitive and psychological well-being symptoms in patients with CKD. A total of 739 articles were retrieved, 13 of which are included in the present review. All the studies focused on the usability, acceptability, and feasibility of technology-based interventions aimed at psychological symptoms, with no studies targeting cognitive functioning. Technology-based interventions offer feelings of safety, fun, and satisfaction, and they also have the potential to improve CKD patients’ health outcomes regarding their psychological well-being. The diverseness of technologies allows an approximation towards the identification of those types of technologies most frequently used, as well as the symptoms targeted. There was considerable heterogeneity in the types of technologies used for interventions in so few studies, making it difficult to draw conclusive findings with regard to their efficiency. In order to adequately assess the technology-based health interventions effect, future lines of research should consider designing non-pharmacological treatments for the improvement of cognitive and psychological symptoms in this type of patient.
Physical Demands during Official Competitions in Elite Handball: A Systematic Review
Authors: García-Sánchez Carlos , Navarro Rafael Manuel , Karcher Claude , de la Rubia Alfonso
Published: February 2023

An understanding of physical demands during official competitions is essential to achieving the highest performance in handball. The aim of this systematic review was to summarise the available scientific evidence associated with physical demands during official competitions in elite handball according to playing positions, competition level and gender. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, 17 studies were selected after a systematic search and selection process of three digital databases: PubMed, Web of Science and Sport Discus. The quality of the selected studies was evaluated using the Strengthening the Reporting of Observational Studies in Epidemiology checklist; the average score was 18.47 points. The sample consisted of 1175 handball players, of whom 1042 were men (88.68%) and 133 were women (11.32%). The results show that an elite handball player covered on average 3664.4 ± 1121.6 m during a match. The average running pace was 84.8 ± 17.2 m∙min−1. The total distance covered was largely greater in national competitions (4506.7 ± 647.9 m) compared with international competitions (2190.3 ± 1950.5 m) (effect size (ES) = 1.2); however, the running pace did not present any significant difference between the international or national level (ES = 0.06). In regard to gender, the total distance covered was moderately greater in female competitions (4549.1 ± 758.6 m) compared with male competitions (3332.6 ± 1257.7 m) (ES = 0.9), and the running pace was largely greater in female competitions (110.5 ± 7.2 m∙min−1) compared with male competitions (78.4 ± 19.7 m∙min−1) (ES = 1.6). In relation to playing position, backs and wings covered a moderately greater total distance (ES = 0.7 and 0.6) and slightly more meters per minute (ES = 0.4 and 0.2) than pivots. Moreover, the technical activity profile differed between playing positions. Backs performed moderately more throws than pivots and wings (ES = 1.2 and 0.9), pivots exhibited largely more body contact than backs and wings, and wings performed moderately more fast breaks (6.7 ± 3.0) than backs (2.2 ± 2.3) (ES = 1.8). Therefore, this research study provides practical applications for handball coaches and strength and conditioning professionals with respect to designing and implementing more individualised training programmes to maximise performance and reduce injury risk.
Lifestyle Interventions with Mind-Body or Stress-Management Practices for Cancer Survivors: A Rapid Review
Authors: Buro Acadia W. , Crowder Sylvia L. , Rozen Emily , Stern Marilyn , Carson Tiffany L.
Published: February 2023

This rapid review examined current evidence on lifestyle interventions with stress-management or mind-body practices that assessed dietary and/or physical activity outcomes among cancer survivors. Searches were conducted in PubMed, Embase, and PsycINFO based on Cochrane Rapid Reviews Methods Group rapid review recommendations using the keywords “diet,” “physical activity,” “mind-body,” “stress,” and “intervention.” Of the 3624 articles identified from the initial search, 100 full-text articles were screened, and 33 articles met the inclusion criteria. Most studies focused on post-treatment cancer survivors and were conducted in-person. Theoretical frameworks were reported for five studies. Only one study was tailored for adolescent and young adult (AYA) cancer survivors, and none included pediatric survivors. Nine studies reported race and/or ethnicity; six reported that ≥90% participants were White. Many reported significant findings for diet and/or physical activity-related outcomes, but few used complete, validated dietary intake methods (e.g., 24-h recall; n = 5) or direct measures of physical activity (e.g., accelerometry; n = 4). This review indicated recent progress on evaluating lifestyle interventions with stress-management or mind-body practices for cancer survivors. Larger controlled trials investigating innovative, theory-based, personalized interventions that address stress and health behaviors in cancer survivors—particularly racial/ethnic minority and pediatric and AYA populations—are needed.
Risk Perception of the SARS-CoV-2 Pandemic: Influencing Factors and Implications for Environmental Health Crises
Authors: Mc Call Timothy , Lopez Lumbi Susanne , Rinderhagen Michel , Heming Meike , Hornberg Claudia , Liebig-Gonglach Michaela
Published: February 2023

Background: The SARS-CoV-2 pandemic and climate change are two simultaneously occurring large scale environmental health crises. This provides an opportunity to compare the risk perception of both crises in the population. In particular, whether experiencing the acute pandemic sensitizes people to the risks of ongoing climate change. Methods: Panel participants answered a web-based questionnaire. The risk perception of SARS-CoV-2 and influencing factors were assessed. Differences of risk perception dimensions regarding SARS-CoV-2 and climate change were analyzed as well as associations between dimensions. Results: The results show that an economic impact by the pandemic is associated with more dimensions of SARS-CoV-2 risk perception than an experienced health impact. Moreover, dimensions of risk perception of the pandemic and climate change are perceived differently. Furthermore, the affective dimension of pandemic risk perception is significantly associated with all dimensions of climate change risk perception. Conclusions: Emotional-based coping with the risks of SARS-CoV-2 is associated with risk perception of climate change as well as various factors that shape the individuals’ risk perception. It is currently necessary and will be increasingly necessary in the future to solve coexisting crises, not selectively, but in a common context within the framework of a social-ecological and economic transformation.
Inpatient Physical Therapy in Moderate to Severe Traumatic Brain Injury in in Older Adults: A Scoping Review
Authors: Noël Florence , Gagnon Marie-Pier , Lajoie Jasmine , Côté Marjorie , Caron Sarah-Maude , Martin Abygaël , Labrie-Pichette Alexis , Carvalho Livia P.
Published: February 2023

Background: Around 500/100,000 Canadians experience a traumatic brain injury (TBI) resulting in long-term disabilities and premature death. Physiotherapy is known to positively impact the prognosis of young adults following a TBI. Objective: This is a scoping review that aimed to identify research topics in physiotherapy interventions for seniors after a TBI, describe potential knowledge gaps, and uncover needs for future research. Methodology: Ten databases were interrogated (January–March 2022). We included texts published after 2010, in English or French, scientific papers, guidelines, and gray literature sources targeting in-hospital, acute-to-subacute interventions for people aged ≥55 years old with a moderate-to-severe TBI. The outcomes sought were physical/functional capacities, injury severity, and quality of life. Results: From 1296 articles, 16 were selected. The number of participants from the studies altogether was 248,794. We identified eight retrospectives studies, three clinical trials, and five articles from the gray literature. Articles were classified according to the nature of their analysis and outcomes: (1) interventional studies including physiotherapy (at least 10 types of rehabilitative or preventive interventions were identified); (2) studies evaluating prognostic factors (five factors identified); and (3) recommendations from clinical practical guidelines and other sources (gray literature). Our results provide evidence that physiotherapy is effective in TBI acute rehabilitation for the elderly to prevent complications arising from the primary injury and to improve functional capacities. Conclusion: The heterogeneity of our results does not allow us to infer the effectiveness of one intervention over another. However, we found that the elderly population benefits from physiotherapy interventions as much as adults, but the gap must be filled with higher-quality studies to make definite recommendations.
Spatial Difference and Convergence of Ecological Common Prosperity: Evidence from the Yellow River Basin in China
Authors: Liu Pei , Xu Jiajun , Yang Xiaojun
Published: February 2023

Analyzing the spatial difference and convergence of ecological common prosperity (ECP) in the Yellow River Basin (YRB) will be beneficial for the environmental governance and multi-regional economic coordination. Based on the panel data of 97 cities in the YRB from 2003 to 2019, this paper measured and analyzed the index of ECP, the Gini coefficient of ECP, and the convergence of ECP. The results indicate that the ECP of YRB shows a steady growth trend (with an average growth rate of 4.71% yearly) and the overall differences are low (average Gini coefficient is 0.1509 from 2003 to 2019). In different areas, the Gini coefficient between the medium-stream and downstream of YRB is the largest (average value of Gini coefficient is 0.1561). From the decomposition of the overall differences of ECP, the contribution degree of the density of transvariation is the highest for annual average, with a contribution rate of 43.37%, the rate of intra-regional and the inter-regional differences are 31.86% and 24.77%, respectively. The results indicate that the overall differences of ECP in YRB are getting smaller because of cooperation and governance, but the differences between and within regions exist because of geographical feature. There is a significant spatial β convergence trend of ECP, the convergence rate in the upstream and downstream area is faster under the economic geographical matrix than others, and the rate in the medium-stream area is faster under the administrative adjacency matrix. Therefore, strengthening economic and environmental cooperation between and within regions is more beneficial to achieve a better quality of life, as well as the long-term goals of 2035.
Impact of COVID-19 Preventative Measures on Otolaryngology in Taiwan: A Nationwide Study
Authors: Cho Hsiao-Yun , Hung Chia-Hung , Kao Yi-Wei , Shia Ben-Chang , Chen Mingchih
Published: February 2023

Background: Taiwan always had low case rates of COVID-19 compared with other countries due to its immediate control and preventive measures. However, the effects of its policies that started on 2020 for otolaryngology patients were unknown; therefore, the aim of this study was to analyze the nationwide database to know the impact of COVID-19 preventative measures on the diseases and cases of otolaryngology in 2020. Method: A case-compared, retrospective, cohort database study using the nationwide database was collected from 2018 to 2020. All of the information from outpatients and unexpected inpatients with diagnoses, odds ratios, and correlation matrix was analyzed. Results: The number of outpatients decreased in 2020 compared to in 2018 and 2019. Thyroid disease and lacrimal system disorder increased in 2020 compared to 2019. There was no difference in carcinoma in situ, malignant neoplasm, cranial nerve disease, trauma, fracture, and burn/corrosion/frostbite within three years. There was a highly positive correlation between upper and lower airway infections. Conclusions: COVID-19 preventative measures can change the numbers of otolaryngology cases and the distributions of the disease. Efficient redistribution of medical resources should be developed to ensure a more equitable response for the future.
Study of The Impact of Users’ Features on Dimensional Allowances Resulting from the Use of Personal Protective Equipment
Authors: Szkudlarek Joanna , Owczarek Grzegorz , Jachowicz Marcin , Zagrodny Bartłomiej , Sencerek Jędrzej
Published: February 2023

Up-to-date anthropometric data on the human population are needed for designing safe and ergonomically efficient workplaces. An important determinant of safety and ergonomic comfort at work is knowledge of the value of dimensional allowances (DAs) when using personal protective equipment (PPE) as the dimensions and space occupied by workers increase. This is particularly important in environments characterized by spatial constraints. However, it is not well known to what extent the aforementioned DAs are affected by the users’ features. The anthropometric dimensions of 200 people (151 males and 49 females) were obtained from 3D scans, and these became the basis for calculating DAs when using PPE kits normally worn by rescue and technical workers. DAs were determined for the entire body shape of a person wearing three types of PPE kits designed for firefighters, mine rescuers, and welders. In the study, maximum and mean values of height, width, and circumference DAs were obtained. In addition, percentage dimensional increments (DIs) were calculated. A three-dimensional analysis of the human body with and without PPE, involving a 3D scanning methodology, was applied to address the research question. Test results clearly indicate that the values of DAs do not depend on the anthropometric features of users, such as sex, age, and body height percentile—they remain constant for a given type of PPE. The presented data are useful for designing PPE products as well as work tools and infrastructure, including machinery, devices, workstations, means of transport, interiors, and building equipment. The results of the presented study indicate that dimensional allowances play a significant role in interactions between persons wearing PPE and their work environments. The obtained results (DAs and percentage DIs) are included in a new anthropometric atlas of human measures developed by the CIOP-PIB in 2023.
The Effects of Oral Nicotine Pouch Packaging Features on Adult Tobacco Users’ and Non-Users’ Product Perceptions
Authors: Mays Darren , Long Lauren , Alalwan Mahmood A. , Wagener Theodore L. , Shang Ce , Roberts Megan E. , Patterson Joanne G. , Keller-Hamilton Brittney
Published: February 2023

Background: Oral nicotine pouches (ONPs) are novel products that are marketed as “tobacco-free” alternatives to cigarettes and smokeless tobacco (ST). This study examined the effects of ONP packaging features on adult tobacco users’ and non-users’ product perceptions. Materials and Methods: Adult tobacco users (cigarettes, ST, and dual cigarette/ST) and non-users (total N = 301) viewed ONP pack images in a 4 × 3 × 2 between-subject experiment testing the effects of the displayed flavor (cool mint, coffee, dark frost, and smooth), nicotine concentration (none displayed on the package, 3 mg, and 6 mg), and addiction warning label (yes or no). The outcomes were perceived substitutability of ONPs for cigarettes and ST and perceived risks. We modeled the effects of tobacco user status and the experimental factors on these outcomes. Results: All tobacco user groups perceived ONPs to be significantly less harmful and less addictive than non-users. There were significant effects of nicotine concentration on perceived risks. Compared to packages that did not display nicotine concentration, packages displaying 6 mg nicotine concentration produced significantly lower perceived harm (β = −0.23, 95% CI −0.44, −0.02), perceived addictiveness (β = −0.28, 95% CI −0.51, −0.05), risk appraisals of harm (β = −0.50, 95% CI −0.88, −0.12) and risk appraisals of addictiveness (β = −0.53, 95% CI −0.95, −0.11). Conclusions: The study findings demonstrate that the nicotine concentration displayed on ONP packaging can affect adults’ perceptions of ONPs. Further research on the effects of ONP packaging features emphasizing nicotine (e.g., “tobacco free” nicotine claims) on tobacco users and non-users is needed to assess their potential public health impact.
Depression and Medicine Use among Older Adults during the COVID-19 Pandemic: The Role of Psychosocial Resources and COVID-19 Perceived Susceptibility
Authors: Greenblatt-Kimron Lee , Shinan-Altman Shiri , Alperin Mordechai , Levkovich Inbar
Published: February 2023

A relationship was found between the COVID-19 pandemic and depression among older adults and between depressed mood and increased use of antidepressant medication among older adults during the pandemic. With the aim of broadening the understanding of these relationships, the study examined whether COVID-19 perceived susceptibility mediates the relationship between psychosocial resources (optimism and perceived social support) and depressive symptoms and medication use. Participants included 383 older adults (M = 71.75, SD = 6.77) reporting on socio-demographics, health characteristics, depression, optimism, social support, and COVID-19 perceived susceptibility. Medication use was retrieved from participants medical files. Lower optimism, lower social support, and higher COVID-19 perceived susceptibility were associated with greater depression, related with higher medication use. The findings emphasize the buffering effect of psychosocial resources on the adverse effects of depression affecting older adults during the COVID-19 pandemic, and consequently, the increased use of medication in this population. Practitioners should focus interventions on enhancing optimism and expanding social support among older adults. Moreover, interventions focused on alleviating depression among older adults should aim at improving perceptions of perceived susceptibility in the older population.
Danger Zone or Newfound Freedoms: Exploring Women and Girls’ Experiences in the Virtual Space during COVID-19 in Iraq
Authors: Qushua Najat , Gillespie Alli , Ramazan Dechol , Joergensen Sunita , Erskine Dorcas , Poulton Catherine , Stark Lindsay , Seff Ilana
Published: February 2023

During the COVID-19 pandemic, women and girls across the globe faced increased reliance on the digital space to access education, social support, and health and gender-based violence (GBV) services. While research from the last three years has explored how women and girls navigated and responded to their new virtual reality, minimal evidence has been generated from low-resource settings where access to technology may be limited. Further, no studies to date have examined these dynamics in Iraq, where women and girls already face numerous threats to safety due to various forms of structural violence and patriarchal family structures. This qualitative study aimed to examine women and girls’ experiences in the digital space during COVID-19 in Iraq, including the benefits and risks of engagement as well as how access to the digital space was controlled. Data for the present analysis come from the authors’ larger multi-country study investigating women and girls’ safety and access to GBV services in the context of the COVID-19 pandemic and related public health measures employed to control the spread of the virus. In Iraq, semi-structured key informant interviews were conducted virtually with fifteen GBV service providers. Following the translation and transcription of interviews, the thematic analysis highlighted several benefits and challenges women and girls experienced as they tried to access and utilize technology for schooling, support services, and obtaining and spreading information. While many women and girls increasingly and successfully relied on social media to spread awareness of GBV cases, key informants noted that women and girls also faced increased risks of experiencing electronic blackmail. In addition to a substantial digital divide in this context—which manifested as differential access to technology by gender, rural/urban status, and socioeconomic status—intrahousehold control of girls’ access to and use of technology left many adolescent girls unable to continue schooling and contributed to their further marginalization and consequent decline in well-being. Implications for women’s safety and mitigation strategies are also discussed.
Effectiveness of Paliperidone Palmitate in Reducing Acute Psychiatric Service Use for Patients Suffering from Psychosis—A Retrospective Mirror-Image Study
Authors: Chan Chun Ting , Verma Swapna , Subramaniam Mythily , Abdin Edimansyah , Tay Jenny
Published: February 2023

Poor adherence to antipsychotic treatment is a leading cause of relapse for patients suffering from psychotic disorders and the use of long-acting injectable antipsychotics (LAI) may lead to improved clinical outcomes. This was a 1-year mirror-image study examining the clinical outcomes after monthly administration of paliperidone palmitate (PP1M). The primary outcome measure was the total days of psychiatric hospitalization in the 1-year before and 1-year after initiation of PP1M. Data from 158 patients were included in the study. Most of the patients suffered from schizophrenia. In the year after initiation of PP1M, the mean number of hospitalization days fell from 106.53 to 19.10 (p < 0.001). There were significant reductions in the mean number of hospitalizations and emergency room visits. The use of paliperidone palmitate is associated with significant reduction in both the number of admissions and days of psychiatric hospitalization.
Digital Transformation in Healthcare: Technology Acceptance and Its Applications
Authors: Stoumpos Angelos I. , Kitsios Fotis , Talias Michael A.
Published: February 2023

Technological innovation has become an integral aspect of our daily life, such as wearable and information technology, virtual reality and the Internet of Things which have contributed to transforming healthcare business and operations. Patients will now have a broader range and more mindful healthcare choices and experience a new era of healthcare with a patient-centric culture. Digital transformation determines personal and institutional health care. This paper aims to analyse the changes taking place in the field of healthcare due to digital transformation. For this purpose, a systematic bibliographic review is performed, utilising Scopus, Science Direct and PubMed databases from 2008 to 2021. Our methodology is based on the approach by Wester and Watson, which classify the related articles based on a concept-centric method and an ad hoc classification system which identify the categories used to describe areas of literature. The search was made during August 2022 and identified 5847 papers, of which 321 fulfilled the inclusion criteria for further process. Finally, by removing and adding additional studies, we ended with 287 articles grouped into five themes: information technology in health, the educational impact of e-health, the acceptance of e-health, telemedicine and security issues.
Applying Landscape Ecology in Local Planning, Some Experiences
Authors: Eikaas Inger-Lill , Roussel Helene , Thorén Anne-Karine H. , Dramstad Wenche E.
Published: February 2023

Landscape ecology is repeatedly described as an applied science that can help reduce the negative effects of land-use and land-use changes on biodiversity. However, the extent to which landscape ecology is in fact contributing to planning and design processes is questioned. The aim of this paper is to investigate if and how landscape ecology can be integrated in a planning and design process, and to uncover possible problems that, e.g., landscape architects and planners, may face in such processes. Our conclusion, based on a case study from Asker municipality, Norway, is that such a landscape ecological approach has a lot to offer. However, it is difficult to exploit the potential fully for different reasons, e.g., biodiversity information tends to be specialized, and not easily used by planners and designers, and landscape ecological principles need an adaptation process to be applicable in a real-world situation. We conclude that for the situation to improve, landscape ecologists need to ease this process. In addition, we recommend collaboration across disciplinary boundaries, preferably with a common design concept as a foundation.
The Effect of Neoglandin on the Activity of N-Acetyl-β-D-Hexosaminidase in the Serum and Urine of Alcohol-Dependent Men
Authors: Szajda Sławomir Dariusz , Dobryniewski Jacek , Minarowska Alina , Snarska Jadwiga , Waszkiewicz Napoleon , Zwierz Krzysztof
Published: February 2023

Dietary supplementation of gamma-linolenic acid (GLA) in the form of a commercial drug neoglandin (containing GLA and vitamin E), in people following alcohol abuse allows bypassing of the ineffective delta-6-desaturase system involved in the transformation of linoleic acid into GLA. Determination of the activity of N-acetyl-β-D-hexosaminidase (HEX) in the serum and urine reflects neoglandin action on the catabolism of glycoconjugates and the functioning of liver and kidneys in people following alcohol abuse. Material and methods: The serum and urine were collected from men with alcohol dependence, treated (n = 31, age 33.16 ± 9.72 years) and not treated (n = 50, age 35.46 ± 11.37 years) with neoglandin. HEX activity were assayed in the supernatants by the colorimetric method, with the p-nitrophenyl derivative of sugar as substrate. Results: Our study on alcoholic men not treated with neoglandin indicates a significantly higher concentration of the serum and urinary HEX activity (nKat/L) on day 1 compared to days 7, 10, 14 and 30 (p < 0.001). For days 14 and 30 (p < 0.01), the urinary HEX activity was expressed in μKat/kgCr. No significant differences were observed in the activity of serum (nKat/L) and urinary (nKat/L and μKat/kgCr) HEX in alcoholics during treatment with neoglandin compared to day 1 of neoglandin treatment. We found significantly different (p < 0.05) concentration of HEX activity (nKat/L) in serum of alcohol-dependent men treated with neoglandin compared to those not taking neoglandin on days 7, 10, 14 and 30 of treatment. The urinary concentration of HEX activity (nKat/L) on days 1, 4, 10 and 30 and HEX activity in μKat/kgCr on days 1, 4 and 7 it was significantly higher (p < 0.05) during the treatment of alcohol-dependence without the use of neoglandin as compared to alcoholics treated with neoglandin. We found a positive correlation between the amount of alcohol consumed and the urinary activity of HEX in the early phase after alcohol withdrawal and a lack of correlation between the HEX activity in serum and urine of alcohol-dependent men not treated with neoglandin. Conclusions: Neoglandin supplementation in alcoholic men significantly slows down the catabolism of glycoconjugates, thus reducing the effects of ethanol poisoning that are harmful to the kidneys. Neoglandin reduces the harmful effects of ethanol poisoning more on the kidneys than on the liver. The activity of HEX in the serum may be used in monitoring the treatment of alcoholism and whether alcohol reuse occurred during the therapy. In the early stages of alcohol withdrawal, urinary HEX activity can be used as a marker of the amount of alcohol consumed during previous alcohol abuse.
Young Carers’ Needs and Changing Experiences during an Era of Austerity
Authors: Warren Janet L.
Published: February 2023

Many children caring for ill or disabled family members remain ‘hidden’ and ‘invisible’ in our communities. This study is the first to explore patterns of change, over time and throughout austerity, for children with caregiving roles to better understand how their lives differ from those of their non-caregiving peers. A survey of 2154 children, aged 9–18 years in the general population, and a further 21 children, aged 8–18 years and known to be young carers from the same English unitary authority, was conducted to gain an in-depth understanding of children’s perceptions and experiences of what they do to help at home. This study shows that children with caregiving roles remain a distinctive group who assume more domestic and caring responsibilities than their peers, and who also perform many of these activities more frequently than young caregivers in 2001. Approximately 19% of the respondents in the general population showed signs of being in a caring role, double the percentage identified by the author in 2001, 72% of whom were from Black and Minority Ethnic backgrounds. Indicating over time higher levels of unmet needs among parents and other family members who are ill or disabled, these findings have important implications for professional policy, planning and practice across adult and children’s services.
Differences in the Perception Regarding Inclusion Preparation among Teachers at Different Educational Stages
Authors: Triviño-Amigo Natalia , Polo-Campos Irene , Gomez-Paniagua Santiago , Barrios-Fernandez Sabina , Mendoza-Muñoz María , Rojo-Ramos Jorge
Published: February 2023

Inclusive education is fundamental, consisting of enabling all students, irrespective of their characteristics, to receive appropriate education and actively participate in school life. Teachers play an important role in this regard; thus, this study aims to analyze teachers’ perceptions regarding their preparation for inclusion by assessing possible differences depending on the educational stage (early childhood, primary, or secondary education). A total of 1098 Spanish teachers, from Extremadura, responded to three dichotomic answers about their inclusive education preparation perception and the Evaluation of Teachers’ Inclusion Readiness (CEFI-R) questionnaire, a 19-item tool composed of four dimensions: (1) conception of diversity, (2) methodology, (3) support, and (4) community participation. Pearson’s chi-square test was used to assess differences between the dichotomous questions and educational stage; Kruskal–Wallis was used to determine whether the educational stage conditioned the CEFI-R dimensions responses, and the Spearman rho was used to test the association between age groups and the CEFI-R dimensions. Statistical differences were found between secondary education and preschool education and primary education teachers in the dimensions (1) conception of diversity, (2) methodology, and (3) support. Significant differences in dimension (4) community participation between preschool education teachers and secondary and primary education teachers were found.
Efficiency of the Islamic Banking Sector: Evidence from Two-Stage DEA Double Frontiers Analysis
Authors: Mai Xuan Thi Thanh , Nguyen Ha Thi Nhu , Ngo Thanh , Le Tu D. Q. , Nguyen Lien Phuong
Published: February 2023

This paper examines the multi-dimensional efficiency of the Islamic banking sector and its determinants, including the impacts of the COVID-19 pandemic. To do that, we use a novel approach of two-stage data envelopment analysis (DEA) double frontiers to evaluate the overall efficiency of 79 Islamic banks across 16 countries (2005–2020). In the first-stage analysis, we found that the Islamic banking sector experienced an increasing trend in its efficiency and performance, even during the recent pandemic, although it varied across banks and countries. Our empirical results of the second-stage analysis further showed that economic development can help countries both withstand the recent pandemic and improve the efficiency and performance of their (Islamic) banking system. This, in turn, could help speed up the recovery process of the global economy. Since there is evidence that the Islamic banking sector is resilient to the COVID-19 pandemic, it is expected that this sector will be a driving force of such recovery.
Does the Level of Enforcement Shape the Complexity in Accounting Standards?
Authors: Morais Ana Isabel , Pinto Inês
Published: February 2023

This paper examines whether the level of enforcement shapes the complexity in accounting standards. First, in order to identify the level of complexity in accounting standards, we calculated a new measure that conceptualizes accounting complexity based on the theoretical dimensions of multiplicity and diversity. To calculate this new measure, the content of each International Financial Reporting Standard and International Accounting Standard, in 2018, was analyzed. Second, we investigated whether the level of enforcement affects this score, using the number of enforcements published by the European Securities and Markets Authority (ESMA). Our results show that accounting standards with a higher number of enforcements by ESMA are also more complex, suggesting that enforcement is an important factor that explains the level of complexity of an accounting standard. This study is particularly relevant for regulators in the accounting, auditing, and enforcement fields, since it provides evidence of how enforcement contributes to increasing the level of complexity of accounting standards. This study contributes to the debate on the interdependence of enforcement and accounting regulation, showing that enforcement mechanisms can influence accounting standards. This study also calculates a new measure of complexity in accounting standards, rather than using a quantitative proxy.
Multi-Source Data and Machine Learning-Based Refined Governance for Responding to Public Health Emergencies in Beijing: A Case Study of COVID-19
Authors: Yu Demiao , Huang Xiaoran , Zang Hengyi , Li Yuanwei , Qin Yuchen , Li Daoyong
Published: February 2023

The outbreak of COVID-19 in Beijing has been sporadic since the beginning of 2022 and has become increasingly severe since October. In China’s policy of insisting on dynamic clearance, fine-grained management has become the focus of current epidemic prevention and control. In this paper, we conduct a refined COVID-19 risk prediction and identification of its influencing factors in Beijing based on neighborhood-scale spatial statistical units. We obtained geographic coordinate data of COVID-19 cases in Beijing and quantified them into risk indices of each statistical unit. Additionally, spatial autocorrelation was used to analyze the epidemic risk clustering characteristics. With the multi-source data, 20 influencing elements were constructed, and their spatial heterogeneity was explored by screening 8 for Multiscale Geographically weighted regression (MGWR) model analysis. Finally, a neural network classification model was used to predict the risk of COVID-19 within the sixth ring of Beijing. The MGWR model and the neural network classification model showed good performance: the R2 of the MGWR model was 0.770, and the accuracy of the neural network classification model was 0.852. The results of this study show that: (1) COVID-19 risk is uneven, with the highest clustering within the Fifth Ring Road of Beijing; (2) The results of the MGWR model show that population structure, population density, road density, residential area density, and living service facility density have significant spatial heterogeneity on COVID-19 risk; and (3) The prediction results show a high COVID-19 risk, with the most severe risk being in the eastern, southeastern and southern regions. It should be noted that the prediction results are highly consistent with the current epidemic situation in Shijingshan District, Beijing, and can provide a strong reference for fine-grained epidemic prevention and control in Beijing.