bluuebunny/crossref_metadata_2025 huggingface dataset:
Coronaviruses and their relationship with multiple sclerosis: is the prevalence of multiple sclerosis going to increase after the Covid-19 pandemia?
Authors: Lima Maria , Aloizou Athina-Maria , Siokas Vasileios , Bakirtzis Christos , Liampas Ioannis , Tsouris Zisis , Bogdanos Dimitrios P. , Baloyannis Stavros J. , Dardiotis Efthimios
Published: March 2022

The purpose of this review is to examine whether there is a possible (etiological/triggering) relationship between infection with various Coronaviruses, including Severe Acute Respiratory Syndrome-related Coronavirus-2 (SARS-CoV-2), the virus responsible for the Coronavirus disease-19 (Covid-19) pandemia, and Multiple Sclerosis (MS), and whether an increase of the prevalence of MS after the current Covid-19 pandemia should be expected, examining new and preexisting data. Although the exact pathogenesis of MS remains unknown, environmental agents seem to greatly influence the onset of the disease, with viruses being the most popular candidate. Existing data support this possible etiological relationship between viruses and MS, and experimental studies show that Coronaviruses can actually induce an MS-like demyelinating disease in animal models. Findings in MS patients could also be compatible with this coronaviral MS hypothesis. More importantly, current data from the Covid-19 pandemia show that SARS-CoV-2 can trigger autoimmunity and possibly induce autoimmune diseases, in the Central Nervous System as well, strengthening the viral hypothesis of MS. If we accept that Coronaviruses can induce MS, it is reasonable to expect an increase in the prevalence of MS after the Covid-19 pandemia. This knowledge is of great importance in order to protect the aging groups that are more vulnerable against autoimmune diseases and MS specifically, and to establish proper vaccination and health policies.
Lean Leadership
Authors: Dombrowski Uwe , Mielke Tim
Published: March 2022

„Veränderung entsteht durch Führung“ (W.E. Deming) – Diese Erkenntnis setzt sich auch im Zusammenhang mit Ganzheitlichen Produktionssystemen (GPS) durch. Lean Leadership könnte das fehlende Bindeglied zwischen der Anwendung von Lean-Methoden und einem nachhaltigen GPS sein. Aus der Literatur, Studienergebnissen und den praktischen Erfahrungen aus zahlreichen GPS-Einführungen wurden einige Indikatoren für Lean Leadership abgeleitet. Diese ließen sich aus Empfehlungen für eine erfolgreiche Führung in GPS, vor allem aber auch aus Fehlern und Defiziten gewinnen. Aus den Indikatoren konnten Anforderungen formuliert werden, die den fünf Gestaltungsprinzipien Verbesserungskultur, Selbstentwicklung, Qualifizierung, Gemba und zielorientierte Führung zugeordnet wurden. Diese Anforderungen sollen Führungskräften als Richtschnur für die praktische Umsetzung dienen.
Lernfabriken in Deutschland
Authors: Kreimeier Dieter , Prinz Christopher , Morlock Friedrich
Published: March 2022

Lernfabriken oder auch Learning Factories sind in steigender Anzahl in Deutschland zu finden. Sie helfen dabei, sowohl Mitarbeiter als auch Studenten in einem realitätsnahen Fertigungsumfeld zu qualifizieren und in Schwerpunkten, wie z. B. dem Lean Management, zu Experten auszubilden. Wissenstransfer durch Lernfabriken erfolgt dabei auf Basis praxisorientierter Planspiele und ausgewählter Methoden aus der Didaktik. In diesem Beitrag wird eine Übersicht gegeben, wie die Landschaft der Lernfabriken in Deutschland gestaltet ist und wie sich die Lernfabrik des Lehrstuhls für Produktionssysteme an der Ruhr-Universität Bochum von diesen differenziert. Dabei werden sowohl die vorherrschende Lernumgebung diskutiert, als auch die innovativen Ansätze der LPS-Lernfabrik erörtert, wie z. B. die Lernfabrik für Ressourceneffizienz, die Seminare zum Thema Betriebliche Mitbestimmung und Lean Management-Schulungskonzepte.
Szenariogestützte Produktplanung elektrischer Antriebssysteme
Authors: Sachs Carolina , Herrmann Florian , Reiser Marco
Published: March 2022

Die Elektrifizierung des Antriebsstrangs von Kraftfahrzeugen steht derzeit im Fokus zahlreicher Vorhaben. Eine Vielzahl von Einflussfaktoren erschwert jedoch die Planung und Auswahl eines auf die Anforderungen der jeweiligen Anwendung geeigneten Antriebssystems. Der vorliegende Beitrag stellt daher einen Ansatz zur strategischen Produktplanung und -auswahl durch den Einsatz von Werkzeugen der Szenariotechnik dar. Am Anwendungsbeispiel elektrischer Antriebssysteme für Personen- und Nutzfahrzeugen wird das Vorgehen exemplarisch vorgestellt.*
Auftragseinlastung in Überlastsituationen
Authors: Kompa Stefan , Kraut Andreas , Meißner Jan
Published: March 2022

Im Rahmen dieses Beitrags werden Empfehlungen zur Gestaltung einer selbstoptimierenden Auftragseinlastung in Überlastsituationen sowie deren praxisnahe Umsetzung dargestellt. Die praktische Umsetzung sowie die Realisierung der konzipierten Vorgehensweise geschehen im Rahmen des AiF-Projekts „SelfOrder“ des FIR an der RWTH Aachen. Den Ordnungsrahmen des Gestaltungsansatzes bildet der sogenannte „High Resolution Production Management-Ansatz“.
Systemsimulation in der Umformtechnik
Authors: Schenke Christer-Clifford , Penter Lars , Hardtmann André , Großmann Knut
Published: March 2022

Die Anwendung der Simulation in der Umformtechnik beschränkt sich bislang vor allem auf den Einsatz quasi-statischer Modelle zur Unterstützung der Prozessgestaltung. Durch neuere Entwicklungen in der Antriebstechnik stehen heute Pressen mit erheblich gesteigertem Bewegungsvermögen zur Verfügung, was zu angepassten Geschwindigkeitsverläufen und letztlich zu einer erhöhten Dynamik bei der Durchführung von Umformprozessen führt. Die vorgestellten Arbeiten* untersuchen Wege zu einer durchgehenden virtuellen Analyse von Umformprozessen unter Berücksichtigung der statischen und dynamischen Wechselwirkungen zwischen Maschine und Prozess.
Structural, morphological, electrical and optical properties of Zn doped CdTe thin films
Authors:   Department of Applied Sciences & Humanities,, Surabhi S. , Anurag K. ,   Department of Applied Sciences & Humanities,, Kumar S. R. ,   Department of Applied Sciences & Humanities,
Published: March 2022

Cadmium Zinc Telluride (CdZnTe) is a ternary Ⅱ- Ⅵundeviating band gap semiconductor with cubic Zinc blende formation and it is a propitious material for ambient temperature xray as well as gamma ray sensor detectors. Cadmium Zinc Telluride (CdZnTe) thin layer coating were developed on nickel substrate by chemical bath deposition in non-aqueous approach. The as grown films were inspected by X-ray diffraction (XRD), Field emission scanning electron microscope (FESEM), Scanning electron microscope, Fourier transform infrared spectroscopy (FTIR), PL spectra, UV spectra, Raman spectroscopy and FourProbe analysis. Studies tell that as grown films are poly-crystalline in nature along with cubic zinc blende formation. The structural properties like crystallite size, lattice constant, micro strain as well as dislocation density were evaluated. FESEM and SEM analysis reveals that the as developed films are smooth and equal sized uniform spherical grains distributed in single state as well as in cluster form. The average size of grain film is observed to be 12.33 nm. Optical study reveals the broad transmittance escorted by the band gap energy of 2.2eV. Electrical study reveals that resistivity of as grown film is 5.1×105 Ω-cm at room temperature.
Determining Factors of Financial Performance Recovery in BRI During the Covid-19 Pandemic
Authors: Firdauza Damiana Noor , Rahadian Yan
Published: March 2022

Bank Rakyat Indonesia (BRI) succeeded in loan restructuring in the Micro Small Medium Enterprises (MSMEs) segment. Loan restructuring has succeeded in pushing BRI to achieve the highest financial performance. This study aims to determine the success factors of BRI's loan restructuring. The research object is the Credit Restructuring and Recovery Division. This study applies a qualitative case study. Interviews and documentation were used to collect the data. The findings indicate that the critical success factor in dealing with the crisis is ability to adapt to policies change. The debtor's criteria and loan restructuring cycle are critical success factors of BRI's loan restructuring before the restructuring policy is set. The combination of three main components, namely interest rates, extending loan terms, and payment delays, are a determining factor for the success of loan restructuring. There are five components that support the success of loan restructuring, namely loan marketing, loan guarantee, personal values, information and communication, and other party cooperation.
Expression of the EGFR-RAS Inhibitory Proteins DOK1 and MTMR7 and its Significance in Colorectal Adenoma and Adenoma Recurrence
Authors: Gutting Tobias , Merkel Andreas , Fink David J , Hetjens Svetlana , Weidner Philip , Yu Yanxiong , Kähler Georg , Ebert Matthias P. , Gaiser Timo , Burgermeister Elke , Belle Sebastian
Published: March 2022

Background and Aims: Colorectal adenomas are precursor lesions for colorectal cancer (CRC), a major cause of cancer-related death. Despite all molecular insights, there are still unknown variables in the development of CRC as well as uncertainties regarding adenoma recurrence after resection. We aimed to characterize the expression of docking protein 1 (DOK1) and myotubularin-related protein 7 (MTMR7), which share inhibiting functions on EGFR-RAS-signalling, a major oncogenic driver in CRC, and their association with clinical variables and adenoma recurrence.

Methods: This observational study is based on clinical data obtained from patients who underwent routine endoscopy and consecutive follow-up examinations. Immunohistochemistry was conducted both in dysplastic tissue and adjacent non-dysplastic mucosa followed by microscopical assessment. Recurrence was differentiated between local, segmental and distant relapse.

Results: A total of 56 patients (23 females) gathering 96 adenomas/polyps were included. 36 patients experienced a metachronous lesion, 23 patients had simultaneous lesions in their index endoscopy. Female patients showed lower levels of MTMR7 in adenomas (p=0.0318). Adenomas of young patients showed lower DOK1 than those of older patients (p=0.0469). Big adenomas showed a higher expression of DOK1 than small lesions (p=0.0044). In serrated lesions, DOK1 was reduced (p=0.0026) and correlated with the quantity of lesions (p < 0.001). MTMR7 was significantly reduced in distant (p=0.05) and local segmental recurrence (p=0.0362), while DOK1 showed higher expression in recurrence (p=0.0291).

Conclusions: We found ambivalent results regarding the role of the markers as potential tumor suppressors, implying a context-dependent function of these molecules which might change in the course of time. DOK1 may play an inhibiting role in the serrated pathway. Remarkably, molecular markers have the potential to predict recurrence, since a combined expression analysis of high DOK1 and low MTMR7 correlated with the likelihood of segmental adenoma recurrence.
The Role of Psychotherapy in the Treatment of Patients with Non– alcoholic Fatty Liver Disease and Obstructive Sleep Apnea
Authors: Filipovic Branka F , Latas Milan , Kiurski Stanimir , Al Kiswani Dezbal , Filipovic Natasa , Marjanovic-Haljilji Marija , Laketic Darko , Aksic Milan , Markovic Branka , Kapor Suncica , Kapor Slobodan , Markovic Olivera , Starcevic Ana
Published: March 2022

Background and Aims: Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease with extensive multi- organ involvement, whose extra-hepatic manifestations include diabetes mellitus type 2, cardiovascular disease, obstructive sleep apnea (OSA), chronic kidney disease, and polycystic ovary syndrome. Our hypothesis was that there was a strong psychological component in NAFLD and OSA suffering patients and that psychotherapy would be helpful in the treatment of the mentioned diseases.

Methods: Of 144 initially selected patients (with NAFLD, obesity and OSA), 32 patients agreed to undergo psychotherapy, and 31 therapy-naive NAFLD and OSA patients agreed to participate as controls.

Results: Psychological evaluation revealed that self-esteem rose significantly after one-year psychotherapy (p=0.005). Body mass index (BMI) was significantly lower after psychotherapy, followed by the changes in laboratory results. Binomial logistic regression revealed that the reduction of BMI in high probability led to self-esteem improvement (p=0.03).

Conclusions: Psychotherapy was an efficient supporting method in the treatment of patients with NAFLD, obesity and OSA. It raised self-esteem and stimulated the motivation for further treatment of obesity, as one of the important factors for NAFLD and OSA. Still, it is advisable to use psychotherapy in combination with other clinical methods of treatment.
Visceral Varicella-Zoster Virus Infection in An Immunocompromised Patient: Uncommon Endoscopic Differential Diagnosis
Authors: Moser Benjamin , Fischer Christian
Published: March 2022

Varicella-Zoster virus (VZV) infection is well-known for its dermatological appearances, such as chickenpox and shingles. In addition to its dermal disease, we report a case of visceral dissemination of VZV in immunocompromised patients.

A 38-year-old male Caucasian with a history of bone marrow transplantation due to diffuse large B-cell-lymphoma presented himself with severe abdominal pain. Immediate endoscopy revealed numerous gastric and duodenal ulcerations, while histological and molecular evaluation on tissue biopsies and blood samples confirmed VZV infection. Positive serological findings and history of chickenpox during childhood supported visceral VZV dissemination due to reactivation of VZV. The patient received Aciclovir treatment and fully recovered.

This case illustrates that visceral dissemination of VZV may lead to acute abdominal pain due to severe mucosal ulcerations even in the absence of dermatological manifestations. Early endoscopic evaluation may therefore be crucial and the only means to immediately guide differential diagnosis, especially in immunocompromised patients. Characteristic histomorphological findings from mucosal ulcerations should lead to the immediate initiation of antiviral therapy and specific molecular evaluation in order to avoid detrimental spread of visceral VZV infection.
Clinical Relevance of Anti-Gliadin Seropositivity in the Ageing Population: A Long-term Follow-up Study
Authors: Ruuskanen Anitta Tellervo , Luostarinen Liisa , Huhtala Heini , Valve Raisa , Kaukinen Katri
Published: March 2022

Aims: To explore if anti-gliadin antibody (AGA) positivity is associated with overall mortality or morbidity and especially with the development of coeliac disease during long-term gluten exposure.

Methods: The study population comprised 130 persistently AGA-positive but transglutaminase-2 (anti- TG2) -negative and 52 persistently AGA- and anti-TG2 -negative subjects aged 64-88 years. HLA-typing for DQ2 and DQ8 (coeliac-type HLA) was performed on the AGA-positives. The medical records of the study population were reviewed to compare mortality and morbidity during a long-term follow-up of 12-13 years since the initial antibody analysis.

Results: Mortality or cumulative prevalence of gastroenterological, autoimmune, psychiatric, cardiovascular or any malignant diseases did not differ statistically between the AGA-positives and the AGA-negatives. Neurological diseases were more common in the AGA-negative group (p=0.017), but there was no statistical difference between the prevalence of any particular neurological diseases. Coeliac-type HLA in AGA-positive subjects did not influence mortality or morbidity. However, during the last six to seven years the incidence of immunological diseases was more common in the AGA-positive subjects without coeliac-type HLA than in those with coeliac-type HLA, or in the AGA-negative group (p=0.020). None of the persistently AGA-positive subjects developed clinically diagnosed coeliac disease.

Conclusions: Gliadin antibody positivity without coeliac disease does not predict mortality or morbidity in the ageing population continuing to consume gluten for over ten years.
The Effect of Linked Color Imaging for Adenoma Detection. A Meta-analysis of Randomized Controlled Studies
Authors: Wang Jun , Ye Chuncui , Wu Kejian , Fei Sujuan
Published: March 2022

Background and Aims: The effect of linked color imaging (LCI) compared with white light imaging (WLI) is conflicting. The aim of this meta-analysis is to compare the efficacy of LCI versus WLI for the adenoma detection.

Methods: PubMed, Embase, Google Scholar and Cochrane Library were searched up to the end of Aug 18, 2021. All randomized controlled trials (RCTs) comparing LCI with WLI were included. Dichotomous data were pooled to obtain the relative risk (RR) with a 95% confidence interval (CI), whereas continuous data were pooled using a mean difference (MD) with 95%CI.

Results: A total of 10 RCTs involving 5,510 patients were included. The use of LCI was associated with a statistically significant improvement in adenoma detection rate (ADR), polyp detection rate (PDR), mean adenomas per patient (MAP) and mean polyp per patient (MPP) when compared to WLI (ADR: RR=1.15, 95%CI: 1.07-1.23, p=0.0001, PDR: RR=1.15, 95%CI: 1.08-1.22, p<0.0001; MAP: MD=0.18, 95%CI: 0.09- 0.28, p=0.0002; MPP: MD=0.13, 95%CI: 0.01, 0.25, p=0.03). When stratified by size, LCI group had a higher detection rate of small adenomas (<10 mm) than the WLI group. Besides, LCI showed a significant decrease in adenoma miss rate (AMR) when compared to WLI. There were no statistically significant differences between the two groups in advanced ADR (AADR), sessile serrated lesion detection rate (SDR), cecal intubation rate, insertion time, and withdrawal time.

Conclusions: The pooled evidence suggests that LCI can significantly improve the detection of ADR, especially for small adenomas (<10 mm). Moreover, the AMR were significantly lower using LCI compared with WLI.
Blood Metabolomic Signatures to Identify Bacterial Infection in Patients with Decompensated Cirrhosis
Authors: Fischer Petra , Pandrea Stanca , Grigoras Crina , Stefanescu Horia , Farcau Oana , Tefas Cristian , Socaciu Carmen , Procopet Bogdan , Ionescu Daniela
Published: March 2022

Background and Aims: Bacterial infections are associated with high mortality rates in patients with decompensated cirrhosis. Early diagnosis with the available diagnostic tools is challenging. Metabolomics is a novel technique with a widespread application in hepatology. The aims of our study were to find new biomarkers for decompensated cirrhosis and for those with overlapping bacterial infections.
Methods: 43 patients with compensated and 54 patients with decompensated cirrhosis were enrolled in the study. In patients with decompensation, a complete infectious workup was performed at admission. Blood and ascitic fluid were collected and stored at -80° C until performing the metabolomic analysis. Statistical analysis was performed using the Metaboanalyst 4.0 software.
Results: 36 patients (66%) in the decompensated group were infected. Among them, 15 had multiple infections; thus, finally, 52 infections were diagnosed. The main metabolic pathways affected in patients with decompensated cirrhosis were those related to lipid metabolism, involving acylcarnitines, stearic acid derivatives, and 12/15 HETE-GABA. N-oleoyl ethanolamine was the most promising biomarker for bacterial infection diagnosis. Moreover, prostaglandin E2/D2/H2 and N-oleoyl alanine levels were higher in Gram- positive infections and ceramides (d16:2/18:0), in Gram-negative infections, respectively. L-phenylalanine (m/z=166.09) and lysophosphatidylethanolamine (18:3/0:0) were the two most relevant identified ascitic biomarkers for spontaneous bacterial peritonitis diagnosis.
Conclusions: The lipid and energetic metabolic pathways were the most affected in patients with decompensated cirrhosis and those with overlapping infections.
Deafspace no Ciberespaço
Authors: Garcia Maria Izabel dos Santos , Cabral Rebeca Garcia
Published: March 2022

Atualmente cerca de 152 milhões de brasileiros usam a internet, sendo considerado o quinto país mais conectado à rede no mundo. Nesse mundo virtual, os surdos vêm se tornando um grupo cada vez mais usuário dessa ferramenta comunicacional. Aqueles que dominam somente a Língua Brasileira de Sinais (Libras) como meio de comunicação – grande maioria – contam suas histórias e relatam suas visões de mundo a partir de uma modalidade linguística gesto- -visual, cuja principal forma de apreensão é a produção do texto imagético. Em geral, as línguas de sinais de cada país ainda são ágrafas, ou seja, não possuem uma forma de grafia consagrada, em parte por conta de sua tridimensionalidade. Desse modo, as redes sociais possibilitaram aos surdos o uso da língua de sinais não só na comunicação com seus pares, mas também na difusão do próprio movimento social em meio às pessoas não surdas. Assim, o presente artigo pretende traçar um debate entre o estudo das tecnologias digitais e o recente uso das redes sociais pelos artistas surdos na visibilidade do movimento social desse grupo através de suas produções artísticas. Para tal, utilizaremos o conceito do “espaço surdo” (deafspace) em diálogo com o ciberespaço e as possibilidades de se produzir ciberativismo.
Situación de la economía digital, el comercio electrónico y el ecosistema FinTech en Uruguay
Authors: Mora-Vega Roy , Fonseca-Arguello Hugo , Murillo-Vega Maricruz
Published: March 2022

El artículo analiza la situación de la economía digital en el Uruguay, particularmente en relación con el comercio electrónico y el surgimiento de empresas FinTech. Este es un sector que refleja la creciente importancia que tiene la economía digital como impulsor de la actividad económica de un país pequeño y en vías de desarrollo. Resalta el potencial que tiene este sector para contribuir a la formalización e inclusión económica y financiera. 

 Se emplea una metodología descriptiva y exploratoria, y una compilación de información de varias fuentes, recurriendo al uso de fuentes secundarias de variables cualitativas y cuantitativas. Una de las conclusiones de este trabajo es que Uruguay, a pasear de ser un país pequeño, es uno de los más avanzados en digitalización en América Latina, sin embargo, siguen existiendo importantes brechas y oportunidades de mejora y crecimiento en este sector.
Vivencias estudiantiles en torno al desarrollo de habilidades en el Trabajo Comunal Universitario Empodero de la Sede del Atlántico, Universidad de Costa Rica
Authors: Sojo-Mora Blanca
Published: March 2022

Con el fin de identificar el impacto formativo del trabajo comunitario en personas universitarias, se realizó una investigación mixta en la que se describen y cuantifican frecuencias de respuesta. El objetivo de este estudio fue conocer si existe desarrollo de habilidades en estudiantes que realizaron el Trabajo Comunal Universitario, desde sus vivencias estudiantiles. Se aplicó un cuestionario a 24 estudiantes, quienes cumplieron 7.200 horas de trabajo en las comunidades. Se concluye que existen habilidades que tienen mayor desarrollo, como la colaboración y el trabajo en equipo, flexibilidad y adaptabilidad, creatividad, comunicación y respeto por las demás personas.
Actividades lúdicas para fortalecer el pensamiento lógico-matemático en los estudiantes de grado quinto
Authors: Quintero-Bacca Astrid
Published: March 2022

La presente investigación se basó en un estudio mixto mediante el cual a través de entrevistas semiestructurada se abordó la percepción del docente en el contexto actual de la institución educativa, paralelamente abordando con ellos alternativas basadas en la lúdica para dinamizar los procesos de aprendizaje dentro del aula de clase dado el bajo rendimiento reportado típicamente a final de periodo. Este proceso permitió establecer las falencias que presenta el colegio en material didáctico, lo cual limita significativamente la interiorización de estos procesos dentro de la planeación académico, así como también influye la apatía de algunos docentes y la rutina estandarizada que, excluye indirectamente toda iniciativa tendiente a la lúdica. En respuesta a este panorama, se formuló un portafolio de actividades lúdicas de fácil aplicación en el aula, basadas en el trabajo colaborativo y participación activa de los estudiantes, coordinados por el docente, permitiendo un mayor protagonismo del alumno. Así las cosas, esta investigación permitió establecer la multiplicidad de factores que intervienen en un problema, en este caso, la dificultad en la aplicación de la lúdica en el aula obedece a cuestiones de disponibilidad de recursos, actitud docente y del estudiante; además de la apatía al cambio de metodología de enseñanza, principalmente en docentes de avanzada edad. Así pues, la reflexión que deja es a la innovación, a la búsqueda de alternativas que permitan mejores y más motivantes espacios de aprendizaje, basados en un protagonismo significativo del estudiante y la creatividad del docente.
Déficit en el pensamiento espacial y su repercusión en el aprendizaje de la geometría en estudiantes de basica primaria colegio integrado la llana, tibu – norte de santander
Authors: Gonzáles Edinson Orlando
Published: March 2022

La presente investigación tuvo como objetivo central determinar los déficits en el desarrollo espacial y, como estos también repercuten en las experiencias de aprendizaje de los estudiantes. Metodológicamente, este estudio se desarrolla dentro del enfoque investigativo cualitativo, bajo un diseño descriptivo de los hallazgos encontrados en relación a las categorías que surgieron como producto del procesamiento y la triangulación de objetivo, además del marco teórico debidamente establecido. Los resultados del estudio, identifican una realidad en este contexto socioeducativo y cultural en relación a la enseñanza del pensamiento espacial y la geometría, los cuales inciden de forma directa e indirecta en la práctica pedagógica del maestro y la formación integral de los estudiantes. Así mismo el estudio permite a los docentes que imparten educación matemática a realizar una reflexión pedagógica sobre la importancia del pensamiento espacial y la geometría en la vida cotidiana de sus estudiantes.
Historical Trauma, Queer Sex, and Physical Touch in Barbara Hammer’s Nitrate Kisses
Authors: Lallouz Rachel
Published: March 2022

For lesbian-feminist filmmaker Barbara Hammer, “making up” lost queer history in the absence of conventional archives is a material and embodied process seen in her experimental documentary Nitrate Kisses (1992). This film centres around different queer couples portraying various erotic, physical and sexual acts. Each of these acts are aligned with voice-over interviews and visual archival ephemera detailing particular historical traumas, including the AIDS crisis and the erasure of lesbian experiences from life narratives of Holocaust survivors. I argue that the body and various erotic acts in Nitrate Kisses become sites of consciousness and cognition employed in the recovery of traumatic memory. As I explore, it is physical touch—sexual and erotic touch in particular—that acts as a conduit for accessing lost or purposefully invisibilized archival knowledge. Employing Elizabeth Freeman’s erotohistoriography, I argue that sex and other forms of physical touch in Hammer’s film become a method of remembering historical injustices, making them visible through an embodied queer-feminist archival practice in order for the viewer to bear witness to trauma that has shaped queer cultural memory.

This article contains images of nudity and sexual behaviour.
KANO Model: A study to identify important attributes for customer satisfaction in a shoe store
Authors: Pereira Gustavo Alves , Souza Wiliam Santos , De Jesus Willyans Santos , Muniz Emerson Cleister Lima , De Souza João Artur
Published: March 2022

Purpose – To identify which requirements are most important for generating customer satisfaction in a footwear company, through the application of the KANO Model.Design/methodology/approach – A questionnaire was applied by non-probabilistic sampling to collect information, created based on the literature on the subject under study. To ensure its reliability, Cronbach's α was applied as a parameter. For analysis and categorization of requirements, the research followed the guidelines of the Kano Model.Findings – The requirements are framed in mandatory, one-dimensional and attractive attributes. Of these, the mandatory attributes, essential to guarantee customer satisfaction, have already been prioritized by management. It was also found that the strategies used by the company meet about 88% of the identified requirements.Originality/value – The prior identification of the main customer requirements in the company's sector, its detailed analysis and categorization into attributes is the key value of the research, bringing direct benefits to management and its customers. The results allowed management to visualize analytically which of its actions directly contribute to customer satisfaction. And which demanded a joint effort from the company, but without adding much value to customer satisfaction. This, in turn, directly contributes to a better strategic alignment of the company's actions, which now prioritize the delivery and improvement of products/services that benefit all stakeholders.Keywords - KANO model. Customer satisfaction. Shoes store. Service improvement.
Mapping organizational culture in the context of a circular economy: a case study for a Brazilian company
Authors: Ferreira Camila dos Santos , Gomes Giovana Monteiro , Natalense Julio Cesar , Roiz Guilherme Augusto , Ometto Aldo Roberto , Gerolamo Mateus Cecílio
Published: March 2022

Purpose – This study aims to answer the following question: “Which organizational culture is embedded in a company that adopts a circular business model?”Theoretical framework – Although the circular economy is gaining a lot of attention from the academia recently, the literature has not been able to address the complexity inherent to this transition from the linear to the circular approach, regarding both a change in the organization and mindset.Design/methodology/approach – The Organizational Culture Assessment Instrument (OCAI) was chosen to identify the culture of the company and its values. The company selected was already in the CE100 network in Brazil so is a best-case scenario to be studied.Findings – The findings show that this company can behave in a way to promote innovation and focus on product development, which are characteristics of the Adhocracy culture profile. The organization also shows a desire to let go of formal and structured processes and embrace behavior that enhance collaboration and teamwork, which are important features of circular businesses. The study concludes that the OCAI methodology was able to show tendencies related to circular businesses.Research, Practical & Social implications – The study is limited since the OCAI method is only applied to one organization. As such, the authors suggest that other organizations be studied.Originality/value – The study discusses the importance of organizational culture and its relationship with the circular economy.Keywords: Circular Economy; Change Management; Culture; Circular Business Model.
Management of pulmonary aspiration due to undiagnosed achalasia during induction of general anesthesia - A case report -
Authors: Kim Hee Jung , Choi Yong Seon , Jin Jeong Hyun , Lee Bora
Published: March 2022

Background: Intraoperative pulmonary aspiration is a rare but potentially fatal complication associated with various risk factors. Preoperative recognition of these risk factors can prevent aspiration events during general anesthesia or facilitate prompt corrective measures in patients experiencing this complication. Case: A 70-year-old female patient with hypertension underwent bilateral total knee arthroplasty under general anesthesia. Despite using a midnight nothing-per-oral (NPO) protocol, an unpredictable intraoperative aspiration event occurred during anesthesia induction. A detailed evaluation of the patient’s medical history and subsequent diagnostic imaging examinations indicated achalasia. She was treated for aspiration pneumonia for 2 weeks. After 2 months, rescheduled total knee arthroplasty was performed under spinal anesthesia without any complications. Conclusions: Obtaining the patient’s medical history and assessing the risk factors are important to prevent unpredictable intraoperative pulmonary aspiration. High-risk patients should undergo adequate preoperative fasting and regional anesthesia or rapid-sequence intubation should be considered for safe induction of general anesthesia.
Teacher Anxiety Scale for Organizing Trips to Out-of-School Learning Environments: Development and Validity of the Scale
Authors: ARIK Selçuk , BOZDOĞAN Aykut Emre
Published: March 2022

This study aims to develop a valid and reliable “Teacher Anxiety Scale for Organizing Trips to Out of School Learning Environments” to measure teachers' anxiety about out-of-school learning environments. This research focuses on the methodological validity and reliability of the scale. The study group of the research consisted of 394 teachers working in public and private schools affiliated to the Ministry of National Education in different cities of Turkey. In the development of the scale, the processes of literature review, creating an item pool, obtaining expert opinion, pilot test, creating the trial form, data collection, data analysis (exploratory factor analysis, repeated exploratory factor analysis, confirmatory factor analysis, item analysis, and reliability analysis), and creating the final form were followed. As a result of the analysis, a valid and reliable scale consisting of 28 items and four factors was created. The factors of the scale were named “Bureaucracy-Related (BR) Anxiety”, “Safety Risks-Related (SRR) Anxiety”, “Harm-Related (HR) Anxiety” and “Pedagogy-Related (PR) Anxiety”, respectively. While the Cronbach’s Alpha reliability coefficient for the total scale was determined as .944; the reliability coefficients for the factors were determined as BR Anxiety Cr α=.868, SRR Anxiety Cr α=.922, HR Anxiety Cr α=.903, and PR Anxiety Cr α=.952, respectively. The results indicate that the scale is quite reliable.
Pattern Recognition: Effectiveness of Teaching Boys Aged 14 the Press Headstand and Handstand
Authors: Mugurdinova Inna , Iermakov Sergii
Published: March 2022

Purpose. To determine the impact of exercise modes on the effectiveness of teaching boys aged 14 the press headstand and handstand.

Materials and methods. The study participants were 20 boys aged 14. The children and their parents were fully informed about all the features of the study and gave their consent to participate in the experiment. To solve the tasks set, the following research methods were used: study and analysis of scientific and methodological literature; pedagogical observation, timing of training tasks; pedagogical experiment, methods of mathematical statistics, discriminant analysis.

Results. The assumption was made about a significant influence of the modes of alternating exercise repetitions and the rest interval on the effectiveness of teaching boys aged 14 the press headstand and handstand. The study found that the mode of 6 sets 1 time each with a rest interval of 60 s is more effective than the mode of 6 sets 2 times each with a rest interval of 60 s when teaching series of training tasks 2, 4, 5, and 6.

Conclusions. The analysis of standardized, structure coefficients, and group centroids revealed that exercise modes significantly influence the process of teaching boys aged 14 the press headstand and handstand during physical education classes. The results of classification of the groups show that 100 % of the original grouped cases were classified correctly
Correlation between temporomandibular disorders and malocclusions: A retrospective observational study-can malocclusions or previous orthodontic treatments affect Temporo-Mandibular Disorders?
Authors: Alessandro Marchesi , Dorothea Bellini , Andrea Sardella , Giulia Fornarelli , Tomson Zefi
Published: March 2022

Background: The purpose of this article is to verify the possible correlation between TMD (Temporomandibular Disorders) and different types of malocclusions in adult subjects and subsequently that between TMD and previous orthodontic treatment. Materials and methods: A retrospective observational study was conducted in San Paolo e Carlo Hospital, associates of the University of Milan, for a period of 2 years (1st February 2019 – 3rd March 2020), on 374 adult patients (244 females and 130 males). The subjects underwent an intraoral examination with a gnathological assessment, in order to distinguish those who suffered from TMD and those who did not. Secondly, the patients were subjected to orthodontic examination to identify those who had previously undergone orthodontic treatment, assessing through an extraoral and intraoral examination, the dental class, the type of dental bite and the presence or absence of a midline deviation. Results: The data analysis revealed a statistically significant association between TMD and gender (p= 0.023, OR= 1.66). The association between class I, II, III malocclusions and the presence of TMD was found to be statistically significant: p<0.0001 (OR= 4.04) and that between open/deep bite and the presence of TMD too: p= 0.003 (OR= 1.89). Moreover, the correlation between midline deviation and the presence of TMD was statistically significant: p<0.0001 (OR=7.48). On the other hand, no correlation was found between TMD and previous orthodontic treatment (p= 0.918). Conclusions: The available data revealed a statistically significant association between TMD and malocclusions, related to dental class and bite and midline deviation, although the existing results in the literature are controversial regarding this association. While no statistically significant correlation was found between TMD and previous orthodontic treatment. Orthodontic therapy, therefore, by correcting occlusion anomalies, could reduce the risk of TMD incidence. Finally, longitudinal studies with adequate statistical power are needed to clarify the possible interrelationships between TMD and malocclusions.
Acute kidney infarction: Not so rare renal disease. A single-center experience with endovascular fibrinolytic therapy
Authors: Scarpioni R , De Amicis S , Bodini Bodini FC , Albertazzi V , Michieletti E
Published: March 2022

Renal Infarction (RI), a rare cause of renal damage characterized by the abrupt interruption of flow in the renal artery, is often recognized late or may even remain undiagnosed since symptoms are non-specific and may be confused with other pathologies, such as pyelonephritis or nephrolithiasis. In situ thrombosis and thromboembolism are the main causes, but often the real cause is, gf unrecognized. The disease is often underdiagnosed and the diagnosis of certainty can be established with ultrasonography Doppler of renal arteries or with second-level diagnostic tools (contrast-enhanced computer tomography, magnetic resonance with gadolinium, and renal scintigraphy) or third level tests (renal arteriography). The therapeutic approach depends on the cause of RI, from the time from onset of ischemia, from the presence of kidney function impairment, and may include systemic anticoagulant therapy, renal angioplasty with or without stenting, loco-regional endovascular fibrinolytic therapy or surgery, as the last chance. In literature, there are neither guidelines nor evidence about any treatment superiority. Here we describe a paradigmatic case in a 51-years-old man hospitalized because of sudden flank pain: the clinical picture, the high serum level. Moreover, we report our 7-years’ experience with 24 cases of RI, mean age 70 /±15 years, 14/24 men, 16/24 presented with hematuria, frequently associated with the history of CKD (16/24). Fifteen of them (62%) were classified as idiopathic and 9 of them were successfully treated with endovascular fibrinolytic treatment. A review of the literature is also provided.
Design and preparation of EcoFAB-N v2
Authors: Weiqi Kuang , not provided Ssanow , not provided Jkelm , Mark Müller-Linow , Peter Andeer , Dietrich Kohlheyer , Trent Northen , not provided jpvogel , Michelle Watt , Arsova Borjana
Published: March 2022

This protocol describes the production of the EcoFAB-N chamber published in the study Kuang et al., "N-dependent dynamics of root growth and nitrate and ammonium uptake are altered by bacteria Herbaspirillum seropedicae in cereal modelBrachypodium distachyon" The volume of the EcoFAB-N chamber is 4 mL. The mold is re-designed using SolidWorks 2017 software (Fig SM1) and the 3D printer files are available as attachments to this protocol. Figure: EcoFAB-N mold. All in one, single piece EcoFAB-N (a) compared to components of EcoFAB mold from Sasse et al 2019 (frame (b); base (c); insert (d)), the insert (d) is used in both molds.
Stranded Mapping from Oriented Long Reads v8
Authors: A Eccles David
Published: March 2022

This protocol demonstrates how to map strand-oriented long reads to a genome, and visualise them in a genome browser. The general idea is to use minimap2 to create stranded BAM files, which are split for forward/reverse orientation then converted into BigWig format for display in a genome browser. Input(s): stranded fastq files (see protocol Preparing Reads for Stranded Mapping) a FASTA file containing the genome / sequence of interest. Output(s): Genome-mapped stranded BAM files Genome-mapped stranded BigWig files
Establishment of craniofacial exocrine gland organoid magnetic bioassembly platforms as aging multi-omic signatures v1
Authors: Rodboon Teerapat
Published: March 2022

In the last decade, relevant biotechnology advances took place in the biofabrication of craniofacial exocrine gland organoids mimicking lacrimal and salivary glands. Though certain challenges still remain not only due to the lack of protocols for organoid reproducibility but also towards the scarcity of methodologies for creating preclinical disease models with aging multi-omic signatures. Previously, our research group successful developed three-dimensional (3D) bioassembly technologies towards the generation of functional epithelial gland-like organoids via magnetic 3D bioprinting platforms (M3DB). To meet the needs of our aging Asian societies, a next step was taken to design consistent M3DB protocols for bioengineering organoid models with aging molecular and pathological features for lacrimal glands (LG) and salivary glands (SG). Herein, we established a feasible step-by-step protocol for producing both LG and SG organoids using M3DB platforms. Such a protocol provided reproducible preliminary outcomes resembling LG/SG organoids. Both acinar and ductal epithelial compartments were prominent (21 4.32% versus 426.72% of total cells, respectively), and could be clearly identified in these organoids. Meanwhile, these can be further developed into aging signature models by inducing cellular senescence via chemical mutagenesis. The generation of senescence-like organoids is our ultimate milestone aiming towards high throughput applications for drug screening and discovery and gene therapy investigations to reverse aging.
SORPSİYON İZOTERMLERİNİN KURUTMA VE DEPOLAMA PROSESLERİNDE ÖNEMİ : KAHRAMANMARAŞ TARHANASI ÖRNEĞİ
Authors: KOCABAŞ Beyza Nur , DOĞAN İnci
Published: March 2022

Ülkemizin elverişli iklim koşulları birçok gıdanın kurutularak muhafazasına olanak sağlamaktadır. Kurutulmuş gıdalar uzun süre bozulmadan korunabilmektedir. Depolama süresince küf ve bakteri oluşumunun ve muhtemel kalite kayıplarının önlenmesi ürünlerin nem oranının kritik değerin altına düşürülmesiyle mümkündür. Kahramanmaraş tarhanası yöreye özgü olup yüzyıllardır çorbalık ve atıştırmalık olarak tüketilen fermente kurutulmuş bir gıdadır. Geleneksel üretiminde güneşte kurutma kullanılmakta olup son yıllarda endüstriyel üretimi de giderek artan ilgi görmektedir. Yaz aylarında kurutulan tarhana kışın tüketilmek üzere depolanmaktadır. Depolamadaki olumsuzluklar tarhanada istenmeyen fiziksel, kimyasal, mikrobiyel ve duyusal kalite kayıplarına yol açmaktadır. Kurutulmuş tarhananın kalite parametrelerinin belirlenmesinde sorpsiyon izotermlerinden faydalanılmaktadır. Sorpsiyon izotermleri sabit sıcaklıkta tutulan gıdanın nem içeriği ile depo ortamının bağıl nemi arasındaki ilişkiyi açıklamaktadır. Sorpsiyon izotermleri su ve gıda bileşenleri arasındaki etkileşimin ve optimum depolama koşullarının tahmin edilmesinde önemli bir termodinamik yardımcıdır.

Bu açıdan çalışmanın amacı sorpsiyon izotermlerinin gıdalar ve Kahramanmaraş tarhanası üzerindeki önemi ve sorpsiyon izotermlerinin oluşturulmasında esas alınan matematiksel modeller hakkında literatürdeki son çalışmalar ışığında bilgiler verilmesidir.
Season, Sex and Size related Diet of Grass Goby, Zosterisessor ophiocephalus (Pallas, 1814) in the Eastern Adriatic Sea
Authors:   Paying Agency for Agriculture Fisheries and Rural Development, Zagreb, Croatia, Đođo Željana , Antolović Nenad , Bratoš Cetinić Ana , Glavić Nikša
Published: March 2022

Feeding habits of Grass goby, Zosterisessor ophiocephalus (Pallas, 1814) related to season, sex and size were examined during one year. Stomach contents of 302 specimens were examined, of which 91 stomachs were empty. The sampled population consisted of 136 females (45.03%) ranging from 6.8 to 19.3 cm (13.30 ± 2.24), 156 males (51.65%) ranging from 6.1 to 20.2 cm (14.14 ± 2.91) and 10 unspecified (3.31%) individuals of a length of 5.6 to 16.0 cm (10.07 ± 2.91). Grass goby is mainly carnivorous. The dietary preferences among sexes and sizes did not differ statistically. Results indicate that Grass goby is an opportunistic species that feeds on wide spectrum on prey. Decapods were the most important prey (IRI =3208.49), followed by Osteichthyes (IRI=490.03).
Perspectives of Plastic Pipes use in Shipbuilding and Marine Industry
Authors:   Ivano-Frankivsk National Technical University of Oil and Gas, Ukraine, Panchuk Myroslav , Sładkowski Aleksander , Oleksiienko Serhii , Panchuk Andrii
Published: March 2022

The use of plastic pipelines allows to increase the efficiency of pipeline systems of a ship due to their extraordinary corrosion resistance, a decrease of maintenance frequency, a reduction of total operational costs, and opens a new direction in the use of plastics. The weight of plastic pipelines is considerably less than that of metal ones, which allows to decrease the weight of the vessel by several tons and to increase, due to this, its maneuverability, as well as to decrease fuel consumption, ensure easier passing of all the necessary weight regulations, and optimize vessel operation. The process of installation work performance provides for a possibility of a pre-assembly of structures, the execution of welded, glued, mechanical joints with the help of a minimum set of tools in a confined space, and decreases by 50% the time of pipeline laying on the ship. Moreover, plastic pipe manufacturing creates five times less carbon dioxide emissions, which makes it a significant environmentally-friendly alternative to metal pipes. Therefore, in the cases where it is technically possible, plastic pipelines can be used as a direct substitution of metal pipelines.