bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 - 9 from p53 Is Positively Regulated by miR-542-3p
Authors: Wang Yemin , Huang Jen-Wei , Castella Maria , Huntsman David George , Taniguchi Toshiyasu
Published: March 2023

PDF file - 574KB, Precursor of miR-542-3p induces p53 expression (S1). MiR-542-3p has no effect on p53 mRNA level (S2). Effects of miR-542-3p on p53 expression in multiple cell lines (S3). MiR-542-3p has no effect on expression levels of various modulators of p53 degradation (S4). Actinomycin D induces p53 expression (S5). Amplification of RPS23 transcript (S6). Effects of miR-542-3p and siRPS23 on cell growth (S7). MiR-542-3p Inhibits cell growth independent of RPS23 (S8). miR-542-3p inhibits cell growth independent of p53 (S9).
Supplementary Figure 1 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: March 2023

PDF file - 368KB, Mammary gland morphogenesis and epithelial proliferation of Tg(NCOA1) mice.
Supplementary Figure 2 from Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy
Authors: Lindner Andreas U. , Concannon Caoimhín G. , Boukes Gerhardt J. , Cannon Mary D. , Llambi Fabien , Ryan Deborah , Boland Karen , Kehoe Joan , McNamara Deborah A. , Murray Frank , Kay Elaine W. , Hector Suzanne , Green Douglas R. , Huber Heinrich J. , Prehn Jochen H.M.
Published: March 2023

PDF file - 53K, Temporal protein profiles for HCT-116 cells.
Supplementary Figure 1 from Systems Analysis of BCL2 Protein Family Interactions Establishes a Model to Predict Responses to Chemotherapy
Authors: Lindner Andreas U. , Concannon Caoimhín G. , Boukes Gerhardt J. , Cannon Mary D. , Llambi Fabien , Ryan Deborah , Boland Karen , Kehoe Joan , McNamara Deborah A. , Murray Frank , Kay Elaine W. , Hector Suzanne , Green Douglas R. , Huber Heinrich J. , Prehn Jochen H.M.
Published: March 2023

PDF file - 66K, Temporal protein profiles for HeLa cells.
Supplementary Figure 7 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: March 2023

PDF file - 3369K, JAM-B is expressed on BM endothelial cells of NOD/SCID mice
Supplementary Figure 5 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: March 2023

PDF file - 2674K, Controls for in vivo short-term homing assays
Supplementary Figure 3 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: March 2023

PDF file - 2139K, Effects of anti-JAM-C antibody binding on apoptosis of human B cells
Supplementary Figure 2 from Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis
Authors: Berger Penny L. , Frank Sander B. , Schulz Veronique V. , Nollet Eric A. , Edick Mathew J. , Holly Brittany , Chang Ting-Tung A. , Hostetter Galen , Kim Suwon , Miranti Cindy K.
Published: March 2023

PDF file - 123KB, K14 loss is coincidental with integrin a6 loss.
Supplementary Figure 1 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: March 2023

PDF file - 5664K, Controls for human B cell quantification in NOD/SCID mice
Supplementary Tables 1 - 9 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: March 2023

XLSX file - 2089K, Definition of 50 metrics of MT dynamics (1). Ranking of targets by number of changes in 23 selected metrics of MT dynamics (2). Reproducibility of effects on MT dynamics by 12 selected targets (3). Statistics of experiments in RPE and Meso-33 cells validating NF2 as a regulator of MT dynamics (4). Documentation of oligos used for gene depletion (5). Contains the raw values of of the 50 metrics for each target and movie aquired in primary or secondary screen (6). Comparison of Negctr and Allstar negatove controls for individual days (7). Documents for each of the 70 targets the variation of effects between different oligos of the same target (8). Identification of significant shifts in MT dynamics (9).
Supplementary Figure 4 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: March 2023

PDF file - 1250K, NF2 is a stabilizer of microtubules.
Supplementary Figure 2 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: March 2023

PDF file - 1573K, Validation of anti-NF2 antibody specificity.
Supplementary Figure S3 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: March 2023

Supplementary Figure S3 PDF file - 1079K, Twenty-eight surface markers associated with activation, cytotoxicity, and differentiation were analyzed by flow cytometry on the gated NK population from the PBMC of healthy donors on Day 0 (rest, pre-activation) and Day 11 (activation, post-expansion)
Supplementary Figure S1 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: March 2023

Supplementary Figure S1 PDF file - 29K, Fold expansion of NK cells following co-cultivation of PBMC in IL-2 with irradiated solid tumor (A549, MCF7, Chang, Hela, HT29, MDA-MB-31, SK-BR-3), liquid tumor (CEM, K562, U937, KL-1) and PBMC (allogeneic and autologous) targets are shown
Supplementary Table 1 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: March 2023

PDF file - 55K, SiRNA library used for the centriole overduplication screen.
Supplementary Figure 5 from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: March 2023

PDF file - 44K, Staining for γH2AX (brown) in sections of the intestine from a CK1α-deficient mouse
Supplementary Figure 2 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: March 2023

PDF file - 607K, Endogenous and overexpressed CEP57 localize to the centrosome in U-2 OS/centrin-GFP cells.
Supplementary Table from RNA Trafficking by Acute Myelogenous Leukemia Exosomes
Authors: Huan Jianya , Hornick Noah I. , Shurtleff Matthew J. , Skinner Amy M. , Goloviznina Natalya A. , Roberts Charles T. , Kurre Peter
Published: March 2023

PDF file - 143K, All primers were used in semi-quantitative PCR
Supplementary Methods and References from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: March 2023

Supplementary Methods and References PDF File - 125K, Supplementary methods contains lists of siRNAs, primers and antibodies, and methods for genomic sequencing, RNA-sequencing, RT-PCR, qPCR, soft agar and cell cycle analysis, cell spreading and adhesion assays
Supplementary Figure 9 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: March 2023

PDF file - 122KB, Lymphatic vessel recruitment into fibroblast-stimulated prostate and breast tumors.
Supplementary Figure 8 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: March 2023

PDF file - 135KB, Recruitment of blood vessels into fibroblast-stimulated prostate and breast tumors.
Supplementary Figure 10 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: March 2023

PDF file - 46KB, NOS1 and CXCL14 mRNA expression correlates in human breast cancer data sets.
Supplementary Figure 1 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: March 2023

PDF file - 61KB, CXCL14-stimulation of fibroblasts induces Hmox1 and Nos1.
Supplementary Figure 6 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: March 2023

PDF file - 163K, Homozygous CHD1 deletion in areas of prostatic intraepithelial neoplasia (PIN) and invasive cancer cells. Overwiew of a hematoxylin- and eosin stained tissue section containing areas of PIN (a, b) and invasive cancer (c). Corresponding FISH images show complete loss of CHD1 FISH signals (red) in PIN and cancer cells but not in stroma cells indicated by an asterix. The control FISH signals (green) correspond to centromere 6.
Supplementary Figure Legend from Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation
Authors: Lee Cleo Yi-Fang , Lin Yuan , Bratman Scott V. , Feng Weiguo , Kuo Angera H. , Scheeren Ferenc A. , Engreitz Jesse M. , Varma Sushama , West Robert B. , Diehn Maximilian
Published: March 2023

PDF file - 153K
Supplementary Figure 4 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: March 2023

PDF file - 44K, Overexpression of RB1 and PTEN in PC-3 cells transfected with PSG5L-RB1 and PSG5L-PTEN as compared to the control vector PLNGY. Lysates were analysed for RB1 (a) and PTEN (b) by immunoblot analysis. Tubulin immunoblot served as loading control.
Supplementary Figure 2 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: March 2023

PDF file - 155K, Baseline CHD1 mRNA (a) and protein (b) expression levels in prostate cancer cell lines cells. Efficacy of ectopic overexpression of CHD1 in PC-3 cells on mRNA (c) and protein level (d) by Taqman PCR and immunoblot analysis, respectively.
Supplementary Materials and Methods, Table 1 from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: March 2023

PDF file - 166KB, Supplementary Table 1. Human and murine primer.
Supplementary Figure 5 from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: March 2023

PDF file - 157KB, Fibroblast-derived GDF15/MIC-1 stimulates cytokine production by LNCaP cells.
Supplementary Figure 7 from A Preclinical Assay for Chemosensitivity in Multiple Myeloma
Authors: Khin Zayar P. , Ribeiro Maria L.C. , Jacobson Timothy , Hazlehurst Lori , Perez Lia , Baz Rachid , Shain Kenneth , Silva Ariosto S.
Published: March 2023

PDF file - 29K, Computational modeling of clinical response to therapy.
Supplementary Figure Legends from Effects of Notch Signaling on Regulation of Myeloid Cell Differentiation in Cancer
Authors: Cheng Pingyan , Kumar Vinit , Liu Hao , Youn Je-In , Fishman Mayer , Sherman Simon , Gabrilovich Dmitry
Published: March 2023

PDF - 28K, Legend for Supplemental Figures S1-S2.
Supplementary Figure 2 from Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity
Authors: Risinger A.L. , Li J. , Bennett M.J. , Rohena C.C. , Peng J. , Schriemer D.C. , Mooberry S.L.
Published: March 2023

PDF file - 207K, High magnification electron micrographs (20,000x and 50,000x) of microtubules formed in the presence of 2 mg/ml tubulin with 10 - 30 microM AJ 60 min after tubulin reactions were warmed to 37 degrees C.
Supplementary Table 1 from Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
Authors: Lin Wan-chi , Rajbhandari Nirakar , Liu Chengbao , Sakamoto Kazuhito , Zhang Qian , Triplett Aleata A. , Batra Surinder K. , Opavsky Rene , Felsher Dean W. , DiMaio Dominick J. , Hollingsworth Michael A. , Morris John P. , Hebrok Matthias , Witkiewicz Agnieszka K. , Brody Jonathan R. , Rui Hallgeir , Wagner Kay-Uwe
Published: March 2023

PDF file - 22K, Immunostaining of selected pancreatic cell lineage markers in ducal and poorly differentiated cancerous lesions of Pdx1-Cre/CAG-tTA/TetOMyc transgenic mice.
Supplementary Figure 4 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Authors: Williams Kevin J. , Argus Joseph P. , Zhu Yue , Wilks Moses Q. , Marbois Beth N. , York Autumn G. , Kidani Yoko , Pourzia Alexandra L. , Akhavan David , Lisiero Dominique N. , Komisopoulou Evangelia , Henkin Amy H. , Soto Horacio , Chamberlain Brian T. , Vergnes Laurent , Jung Michael E. , Torres Jorge Z. , Liau Linda M. , Christofk Heather R. , Prins Robert M. , Mischel Paul S. , Reue Karen , Graeber Thomas G. , Bensinger Steven J.
Published: March 2023

PDF File - 92K, Cholesterol content is unchanged in SREBP loss-of-function cells.
Supplementary Figure 1 from Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity
Authors: Kang Tae Heung , Mao Chih-Ping , Lee Sung Yong , Chen Alexander , Lee Ji-Hyun , Kim Tae Woo , Alvarez Ronald D. , Roden Richard B.S. , Pardoll Drew , Hung Chien-Fu , Wu T.-C.
Published: March 2023

PDF file - 2862K, Immune response and disease outcome in tumor-bearing mice treated with chemotherapy and intratumor injection of protein
Supplementary Materials and Methods from LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
Authors: Cox Thomas R. , Bird Demelza , Baker Ann-Marie , Barker Holly E. , Ho Melisa W-Y. , Lang Georgina , Erler Janine T.
Published: March 2023

Supplementary Materials and Methods PDF file - 79K, Detailed descriptions of experimental conditions
Supplementary Figure S3 from LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
Authors: Cox Thomas R. , Bird Demelza , Baker Ann-Marie , Barker Holly E. , Ho Melisa W-Y. , Lang Georgina , Erler Janine T.
Published: March 2023

Supplementary Figure S3 PDF file - 559K, Fibroblast activation and matrix remodelling leads to increased proliferation and colonisation by tumour cells
Supplementary Figure 2 from KLF5 Regulates the Integrity and Oncogenicity of Intestinal Stem Cells
Authors: Nakaya Takeo , Ogawa Seishi , Manabe Ichiro , Tanaka Masami , Sanada Masashi , Sato Toshiro , Taketo Makoto M. , Nakao Kazuki , Clevers Hans , Fukayama Masashi , Kuroda Masahiko , Nagai Ryozo
Published: March 2023

PDF file - 123KB, mRNA expression signal intensities in stem cells of the duodenum of Lgr5 Cre+ Klf5flox/flox mice without Klf5 deletion (x-axis, log) and Lgr5 Cre+ Klf5delta/delta mice (with Klf5 2 deletion) (y-axis, log).
Suppl Fig. S4 from Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors
Authors: Rani Sweta , Corcoran Claire , Shiels Liam , Germano Serena , Breslin Susan , Madden Stephen , McDermott Martina S. , Browne Brigid C. , O'Donovan Norma , Crown John , Gogarty Martina , Byrne Annette T. , O'Driscoll Lorraine
Published: March 2023

Suppl Fig. S4
Suppl Fig. S3 from Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors
Authors: Rani Sweta , Corcoran Claire , Shiels Liam , Germano Serena , Breslin Susan , Madden Stephen , McDermott Martina S. , Browne Brigid C. , O'Donovan Norma , Crown John , Gogarty Martina , Byrne Annette T. , O'Driscoll Lorraine
Published: March 2023

Suppl Fig. S3
Suppl Fig. S2 from Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors
Authors: Rani Sweta , Corcoran Claire , Shiels Liam , Germano Serena , Breslin Susan , Madden Stephen , McDermott Martina S. , Browne Brigid C. , O'Donovan Norma , Crown John , Gogarty Martina , Byrne Annette T. , O'Driscoll Lorraine
Published: March 2023

Suppl Fig. S2
Suppl Fig. S1 from Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors
Authors: Rani Sweta , Corcoran Claire , Shiels Liam , Germano Serena , Breslin Susan , Madden Stephen , McDermott Martina S. , Browne Brigid C. , O'Donovan Norma , Crown John , Gogarty Martina , Byrne Annette T. , O'Driscoll Lorraine
Published: March 2023

Suppl Fig. S1
Supplementary Figure 4 from ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis
Authors: Bid Hemant K. , Roberts Ryan D. , Cam Maren , Audino Anthony , Kurmasheva Raushan T. , Lin Jiayuh , Houghton Peter J. , Cam Hakan
Published: March 2023

PDF file - 408K, deltaNp63alpha induces cell migration.
Supplementary Figure Legend from CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Authors: Ooi Aikseng , Dykema Karl , Ansari Asif , Petillo David , Snider John , Kahnoski Richard , Anema John , Craig David , Carpten John , Teh Bin-Tean , Furge Kyle A.
Published: March 2023

PDF file - 88K
Supplementary Figure 4 from CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Authors: Ooi Aikseng , Dykema Karl , Ansari Asif , Petillo David , Snider John , Kahnoski Richard , Anema John , Craig David , Carpten John , Teh Bin-Tean , Furge Kyle A.
Published: March 2023

PDF file - 614K, Cycloheximide chase assay results indicate that the NRF2-E82G and the NRF2-V36del are more stable than the wild-type NRF2 (NRF2-WT)
Supplementary Figure 1 from Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer
Authors: Feigin Michael E. , Akshinthala S. Dipikaa , Araki Kiyomi , Rosenberg Avi Z. , Muthuswamy Lakshmi B. , Martin Bernard , Lehmann Brian D. , Berman Hal K. , Pietenpol Jennifer A. , Cardiff Robert D. , Muthuswamy Senthil K.
Published: March 2023

PDF file - 99K, Expression of SCRIB mRNA in human breast cancer.
Supplementary Figure 4 from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer
Authors: McCormack Emmet , Silden Elisabeth , West Richard M. , Pavlin Tina , Micklem David R. , Lorens James B. , Haug Bengt Erik , Cooper Michael E. , Gjertsen Bjørn Tore
Published: March 2023

PDF file - 358K, In vitro viability of NB4, NCI-H460 and MDA-MB-231 cells � NTR � CytoCy5S.
Supplementary Figure 6 from NADPH Oxidase NOX4 Supports Renal Tumorigenesis by Promoting the Expression and Nuclear Accumulation of HIF2α
Authors: Gregg Jennifer L. , Turner Robert M. , Chang Guimin , Joshi Disha , Zhan Ye , Chen Li , Maranchie Jodi K.
Published: March 2023

PDF file - 446K, Supplemental Figure 6 Immunohistochemistry for Nox4 and HIF-2alpha in 786-0 NS and KD xenograft explants confirms re-expression of Nox4 in KD tumors with corresponding elevated HIF-2alpha expression. Magnification 200X.
Supplementary Figure 7 from Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression
Authors: Keune Willem-Jan , Sims Andrew H. , Jones David R. , Bultsma Yvette , Lynch James T. , Jirström Karin , Landberg Goran , Divecha Nullin
Published: March 2023

PDF file - 67K, Control or PIP4K2B knockdown MCF10A cells were labelled with 32P-orthophosphate for two hours after which lipids were extracted, deacetylated and the lipid head groups were separated by HPLC. Radioactivity was quantified using an online detector and the data are presented as counts in each head group divided by the total counts + the SD. B. Lipids were extracted from control or PIP4K2B knockdown MCF10A cells and the abundance of PtdIns5P was measured. The data are presented as the pmoles of PtdIns5P/nmol of total lipid phosphate +the SD.
Supplementary Figure 3 from Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression
Authors: Keune Willem-Jan , Sims Andrew H. , Jones David R. , Bultsma Yvette , Lynch James T. , Jirström Karin , Landberg Goran , Divecha Nullin
Published: March 2023

PDF file - 274K, A. Expression profiles from 17 data sets representing 2999 tumors were extracted, normalised and hierarchically clustered according to tumour subtype. The heat map shows the relative transcript expression of genes in order (named on the right) along chromosome surrounding the ERBB2 gene. The ERBB2 and PIP4K2B are labelled in red. B. ACGH array data from the Chin et al study are shown for genes in order on chromosome 17 surrounding the ERBB2 gene. ERBB2 and PIP4K2B are marked in red on the right side.
Supplementary Methods from Chromosome Instability Modulated by BMI1–AURKA Signaling Drives Progression in Head and Neck Cancer
Authors: Chou Chun-Hung , Yang Neng-Kai , Liu Ting-Yun , Tai Shyh-Kuan , Hsu Dennis Shin-Shian , Chen Ya-Wei , Chen Yann-Jang , Chang Cheng-Chi , Tzeng Cheng-Hwai , Yang Muh-Hwa
Published: March 2023

PDF file - 94KB, Includes quantitative PCR, western blot and immunoprecipitation, wound healing assay, transwell invasion assay, HNSCC sample collection, statistical analysis and one supplementary reference
Supplementary Table 1 from Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells
Authors: Kozono Shingo , Ohuchida Kenoki , Eguchi Daiki , Ikenaga Naoki , Fujiwara Kenji , Cui Lin , Mizumoto Kazuhiro , Tanaka Masao
Published: March 2023

PDF file - 75K, Supplementary Table 1: Primers used for quantitative RT-PCR.
Supplementary Table S1 from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma
Authors: Santo Evan E. , Stroeken Peter , Sluis Peter V. , Koster Jan , Versteeg Rogier , Westerhout Ellen M.
Published: March 2023

Supplementary Table S1 XLS file - 186K, Genes regulated in the SY5Y microarray experiments
Supplementary Figures 1 - 3 from USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression
Authors: Schrecengost Randy S. , Dean Jeffry L. , Goodwin Jonathan F. , Schiewer Matthew J. , Urban Mark W. , Stanek Timothy J. , Sussman Robyn T. , Hicks Jessica L. , Birbe Ruth C. , Draganova-Tacheva Rossitza A. , Visakorpi Tapio , DeMarzo Angelo M. , McMahon Steven B. , Knudsen Karen E.
Published: March 2023

PDF file - 176K, Supplementary Figure S1: USP22 Specifically Promotes AR Recruitment to Target Loci. Supplementary Figure 2: Depletion of USP22 can be mediated by multiple sequences.Supplementary Figure S3: AR Ubiquitylation Levels are not Altered in Response to USP22 Depletion.
Supplementary Figure 4 from Trask Loss Enhances Tumorigenic Growth by Liberating Integrin Signaling and Growth Factor Receptor Cross-Talk in Unanchored Cells
Authors: Spassov Danislav S. , Wong Ching Hang , Wong Sunny Y. , Reiter Jeremy F. , Moasser Mark M.
Published: March 2023

PDF file - 82K, Cell aggregation vs cell growth in PyMT tumor cells
Supplementary Methods from Redox Modulation of Adjacent Thiols in VLA-4 by AS101 Converts Myeloid Leukemia Cells from a Drug-Resistant to Drug-Sensitive State
Authors: Layani-Bazar Adi , Skornick Itai , Berrebi Alain , Pauker Maor H. , Noy Elad , Silberman Alon , Albeck Michael , Longo Dan L. , Kalechman Yona , Sredni Benjamin
Published: March 2023

PDF file - 129K
Supplementary Table 1 from A Circadian Clock Transcription Model for the Personalization of Cancer Chronotherapy
Authors: Li Xiao-Mei , Mohammad-Djafari Ali , Dumitru Mircea , Dulong Sandrine , Filipski Elisabeth , Siffroi-Fernandez Sandrine , Mteyrek Ali , Scaglione Francesco , Guettier Catherine , Delaunay Franck , Lévi Francis
Published: March 2023

PDF file - 86K, Irinotecan-induced changes in body weight according to sex and strain. Results from cosinor analysis with 24 + 12 h periodic components.
Supplementary Figure 2 from Inhibition of Protein Kinase CK2 Reduces Cyp24a1 Expression and Enhances 1,25-Dihydroxyvitamin D3 Antitumor Activity in Human Prostate Cancer Cells
Authors: Luo Wei , Yu Wei-Dong , Ma Yingyu , Chernov Mikhail , Trump Donald L. , Johnson Candace S.
Published: March 2023

PDF file - 2492K, Effect of 25D3 in combination with TBBz on CYP24A1 mRNA expression and cell proliferation in PC3 cell.
Supplementary Tables 1 - 4 from Targeting XRCC1 Deficiency in Breast Cancer for Personalized Therapy
Authors: Sultana Rebeka , Abdel-Fatah Tarek , Abbotts Rachel , Hawkes Claire , Albarakati Nada , Seedhouse Claire , Ball Graham , Chan Stephen , Rakha Emad A. , Ellis Ian O. , Madhusudan Srinivasan
Published: March 2023

PDF file - 104K, Supplemental Table S1: Clinicopathological characteristics of whole breast cancer cohort Supplemental Table S2: Clinicopathological characteristics of validation setSupplementary Table S3: Antigens, primary antibodies, clone, source, optimal dilution and scoring system used for each immunohistochemical marker Supplementary Table S4: siRNA constructs for XRCC1 knockdown
Supplementary Figure 3 from Epigenetic States of Cells of Origin and Tumor Evolution Drive Tumor-Initiating Cell Phenotype and Tumor Heterogeneity
Authors: Chow Kin-Hoe , Shin Dong-Mi , Jenkins Molly H. , Miller Emily E. , Shih David J. , Choi Seungbum , Low Benjamin E. , Philip Vivek , Rybinski Brad , Bronson Roderick T. , Taylor Michael D. , Yun Kyuson
Published: March 2023

Expression patterns of the SHH pathway genes in spontaneous Ptch tumors.
Supplementary Movie 2 from Interactions between MUC1 and p120 Catenin Regulate Dynamic Features of Cell Adhesion, Motility, and Metastasis
Authors: Liu Xiang , Yi Chunhui , Wen Yunfei , Radhakrishnan Prakash , Tremayne Jarrod R. , Dao Thongtan , Johnson Keith R. , Hollingsworth Michael A.
Published: March 2023

MOV file - 2625K, Motility S2-013.1A
Supplemental Materials and Methods from Bridging Population and Tissue Scale Tumor Dynamics: A New Paradigm for Understanding Differences in Tumor Growth and Metastatic Disease
Authors: Gallaher Jill , Babu Aravind , Plevritis Sylvia , Anderson Alexander R.A.
Published: March 2023

Supplemental Materials and Methods
Supplementary Figure 4 from p300 Acetyltransferase Regulates Androgen Receptor Degradation and PTEN-Deficient Prostate Tumorigenesis
Authors: Zhong Jian , Ding Liya , Bohrer Laura R. , Pan Yunqian , Liu Ping , Zhang Jun , Sebo Thomas J. , Karnes R. Jeffrey , Tindall Donald J. , van Deursen Jan , Huang Haojie
Published: March 2023

PDF file - 78KB, Western blot analysis of ectopically v5-tagged cyclin B1 and CDK1 in 293T cells.
Supplementary Figure 3 from p300 Acetyltransferase Regulates Androgen Receptor Degradation and PTEN-Deficient Prostate Tumorigenesis
Authors: Zhong Jian , Ding Liya , Bohrer Laura R. , Pan Yunqian , Liu Ping , Zhang Jun , Sebo Thomas J. , Karnes R. Jeffrey , Tindall Donald J. , van Deursen Jan , Huang Haojie
Published: March 2023

PDF file - 266KB, P300 regulates AR proteasome degradation in PCa cells.
Supplementary Figure 6 from Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2
Authors: Lopez-Rivera Esther , Jayaraman Padmini , Parikh Falguni , Davies Michael A. , Ekmekcioglu Suhendan , Izadmehr Sudeh , Milton Denái R. , Chipuk Jerry E. , Grimm Elizabeth A. , Estrada Yeriel , Aguirre-Ghiso Julio , Sikora Andrew G.
Published: March 2023

PDF file - 59K, In this model, nitric Oxide regulates mTOCR1 activation by acting on the TSC1/2 complex through reversible nitrosylation of TSC-2, which blocks TSC1/2 dimerization. In the absence of NO, the TSC1/2 complex suppresses activity of the Rheb GTP-ase, which activates mTORC1 in GTP-bound form. In the presence of NO, the TSC1/2 complex does not form, and Rheb remains active and capable of activating mTORC1 and the downstream mTOR pathway.
Supplementary Figure Legends, Tables 1 - 2 from Genetic Suppression of Inflammation Blocks the Tumor-Promoting Effects of TGF-β in Gastric Tissue
Authors: Ota Mitsuhiko , Horiguchi Masahito , Fang Victoria , Shibahara Kotaro , Kadota Kyuichi , Loomis Cynthia , Cammer Michael , Rifkin Daniel B.
Published: March 2023

PDF file - 108KB, Supplementary Table 1. Primer List. Supplementary Table 2. Distribution of Tgfb1 and Rag2 Genes.
Supplementary Tables S1-S7 from Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers
Authors: Krishnan Vidhya G. , Ebert Philip J. , Ting Jason C. , Lim Elaine , Wong Swee-Seong , Teo Audrey S.M. , Yue Yong G. , Chua Hui-Hoon , Ma Xiwen , Loh Gary S.L. , Lin Yuhao , Tan Joanna H.J. , Yu Kun , Zhang Shenli , Reinhard Christoph , Tan Daniel S.W. , Peters Brock A. , Lincoln Stephen E. , Ballinger Dennis G. , Laramie Jason M. , Nilsen Geoffrey B. , Barber Thomas D. , Tan Patrick , Hillmer Axel M. , Ng Pauline C.
Published: March 2023

Clinical and tissue information on 30 lung cancer patients (S1); Recurrent somatic variants based on presence of the same variant in the COSMIC database or presence of the same variant within the dataset (S2); Variants of the category 'three or more different variants with predicted functional impact within a gene' (S3); Somatic structural variations (S4); Summary of the sequencing statistics by Complete Genomics for 30 tumor/normal paired samples (S5); Validation of somatic variants by Ion Torrent or Sanger sequencing (S6); Validation of EGFR mutations by Sanger sequencing (S7).
Supplementary Materials, Figure Legends, and Tables from Genetic Validation of the Protein Arginine Methyltransferase PRMT5 as a Candidate Therapeutic Target in Glioblastoma
Authors: Yan Fengting , Alinari Lapo , Lustberg Mark E. , Katherine Martin Ludmila , Cordero-Nieves Hector M. , Banasavadi-Siddegowda Yeshavanth , Virk Selene , Barnholtz-Sloan Jill , Bell Erica Hlavin , Wojton Jeffrey , Jacob Naduparambil K. , Chakravarti Arnab , Nowicki Michal O. , Wu Xin , Lapalombella Rosa , Datta Jharna , Yu Bo , Gordon Kate , Haseley Amy , Patton John T. , Smith Porsha L. , Ryu John , Zhang Xiaoli , Mo Xiaokui , Marcucci Guido , Nuovo Gerard , Kwon Chang-Hyuk , Byrd John C. , Chiocca E. Antonio , Li Chenglong , Sif Said , Jacob Samson , Lawler Sean , Kaur Balveen , Baiocchi Robert A.
Published: March 2023

PDF file - 636KB, Supplemental Table S1: information of the GBM lines used in this paper. Supplemental Table S2: information of the patient clinical data for Figure 1. Supplemental Table S3: Percentage of cells positive for staining with PRMT5 in spontaneous high grade astrocytoma from Mut3 strain (GFAP-cre; cisNf1-/+; P53-/-) and normal brain tissue from wild-type control mouse stained by PRMT5 and ki-67 antibody. Supplemental table S4. GBM cell line (U251) was transfected by scramble control or si-PRMT5. Affymetrix microarray genechip was performed in three independent experiments to evaluate genes up-regulated with PRMT5 silencing.
Supplementary Figure 8 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: March 2023

PDF file - 91KB, The knockdown of NDY1/KDM2B is not rescued by exogenous BMI1.
Supplementary Table S2 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: March 2023

Supplementary Table S2. HMGB1 drives the differentiation of MDSC from bone marrow progenitor cells.
Supplementary Figure S4 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: March 2023

Supplementary Figure S4. Tumors from mice treated with anti-HMGB1 mAb tend to have more tumor-infiltrating CD3+ cells.
Supplementary Figure S1 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: March 2023

Supplementary Figure S1. pNF-KB mAb is specific for activated NF-KB.
Supplementary Figure Legend from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 116K
Supplementary Table 2 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 118K, Serum levels of LCN2 in breast cancer patients.
Supplementary Figure 3 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: March 2023

PDF file - 108K, Validation of JAG1, JAG2, NOTCH1 and PSEN1 overexpression in TCGA HNSCC cohort. A, Overexpression of JAG1, JAG2 and NOTCH1 in tumors in comparison to that in normal tissues in the TCGA HNSCC cohort. B, Overexpression of JAG1 and PSEN1 in the tumors with increased copy number gains in comparison to that in the normal tissues as well as to that in the tumors without copy number gains in the TCGA HNSCC cohort. N, normal mucosa; T, HNSCC tumors; -, without JAG1 or PSEN1 copy number gain; +, with JAG1 or PSEN1 copy number gain. Dots, relative expression levels in different tissue samples. Boxes represent the interquartile range (25th-75th percentile) and horizontal lines inside the boxes indicate median. Whiskers indicate the minimum and maximum values. P value was calculated by using t test.
Supplementary Figure 1 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: March 2023

PDF file - 623K, Effects of restoring HIC1 expression in MDA-468 cells.
Supplementary Table 1 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: March 2023

XLS file, 25232K, List of genes.
Fig S1 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: March 2023

PDF file140K, Characterization of ENOX1 antibody
Supplementary Figure 2 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: March 2023

PDF file, 4242K, Induction of a constitutively active form of NFATc1 (NFATc1CA) promotes cancer cell migration.
Supplementary Figure Legends from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 124K
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: March 2023

Supplemental Figure 4. Activation state of T cells in the lungs from WT and Spp1-/- tumor bearing mice and Spp1 expression by the different leukocyte subsets sorted from lungs.
Supplementary Figure 3 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 184K, Inhibition of ATM and ATR impairs upregulation of RAE1 and phosphorylation of IRF3 and TBK1.
Supplementary Figure 6 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: March 2023

PDF file - 57KB, MLL4 Knockdown decreased UTX mRNA and protein levels, but UTX knockdown did not have any significant effect on MLL4 mRNA levels.
Supplementary Figure 1 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: March 2023

PDF file - 164K, Efficiencies of Zbp1, Rig-I, Sting, Tbk1, and Irf3 shRNA-mediated knockdown in BC2 cells.
Supplementary Figure 5 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: March 2023

PDF file - 33KB, UTX or MLL4 knockdown did not have any obvious effect on total cellular levels of H3K27me3 and H3K4me3.
Supplementary Figure 4 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: March 2023

PDF file - 48KB, Two different MLL4 antibodies confirmed that MLL4 is recruited to MMP-9, MMP-11, and Six1 genes.
Supplementary Figure 4 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: March 2023

PDF file - 134K, CLPTM1L Regulates Bcl-xL Accumulation and Protects Mouse Lung Tumor Cells from Genotoxic Apoptosis.
Supplementary Methods, Table 1 from Dramatic Antitumor Effects of the Dual MET/RON Small-Molecule Inhibitor LY2801653 in Non–Small Cell Lung Cancer
Authors: Kawada Ichiro , Hasina Rifat , Arif Qudsia , Mueller Jeffrey , Smithberger Erin , Husain Aliya N. , Vokes Everett E. , Salgia Ravi
Published: March 2023

PDF file - 140K, Supplementary Table S1. Interactive gene networks of Mitogenic signaling of H1993 treatment with LY2801653 (3 nM). MetacoreTM (GeneGo) analysis using the tool 'Analyze network, Build Network'. Note: 'Size' represents the total number of genes evaluated in the Map Folder 'Mitogenic Signaling'. 'Target' denotes the number of genes out of the 12 significant genes that are common to that pathway.
Supplementary Table 7 from Proteogenomic Analysis Reveals Unanticipated Adaptations of Colorectal Tumor Cells to Deficiencies in DNA Mismatch Repair
Authors: Halvey Patrick J. , Wang Xiaojing , Wang Jing , Bhat Ajaz A. , Dhawan Punita , Li Ming , Zhang Bing , Liebler Daniel C. , Slebos Robbert J.C.
Published: March 2023

PDF file - 1190K, MMR status comparison.
Supplementary Figure 5 from Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids
Authors: Nagathihalli Nagaraj S. , Beesetty Yugandhar , Lee Wooin , Washington M. Kay , Chen Xi , Lockhart A. Craig , Merchant Nipun B.
Published: March 2023

PDF file - 86KB, AREG and TGR5 knockdown in CRC and PDAC cells.
Supplementary Table 2 from Cyclin E1 Deregulation Occurs Early in Secretory Cell Transformation to Promote Formation of Fallopian Tube–Derived High-Grade Serous Ovarian Cancers
Authors: Karst Alison M. , Jones Paul M. , Vena Natalie , Ligon Azra H. , Liu Joyce F. , Hirsch Michelle S. , Etemadmoghadam Dariush , Bowtell David D.L. , Drapkin Ronny
Published: March 2023

PDF file - 96K, Differential expression of DNA damage response genes in FT282-CCNE1 cells compared to FT282-V cells.
Supplementary Figure 4 from Slug Promotes Survival during Metastasis through Suppression of Puma-Mediated Apoptosis
Authors: Kim Seaho , Yao Jiahong , Suyama Kimita , Qian Xia , Qian Bin-Zhi , Bandyopadhyay Sanmay , Loudig Olivier , De Leon-Rodriguez Carlos , Zhou Zhen Ni , Segall Jeffrey , Macian Fernando , Norton Larry , Hazan Rachel B.
Published: March 2023

PDF file - 37KB, Supplementary Fig. S4. Slug knockdown sensitizes PyMT-N-cad cells to apoptosis.
Supplementary Figure 5 from Detection of Brain Tumor Cells in the Peripheral Blood by a Telomerase Promoter-Based Assay
Authors: MacArthur Kelly M. , Kao Gary D. , Chandrasekaran Sanjay , Alonso-Basanta Michelle , Chapman Christina , Lustig Robert A. , Wileyto E. Paul , Hahn Stephen M. , Dorsey Jay F.
Published: March 2023

PDF file - 105KB, Supplementary Figure 5. Comparison of EGFR-expressing CTCs from additional patients with EGFR over-expressing high grade glioma and EGFR (-) glioma tumors.
Supplementary Table 7 from Genetic and Phenotypic Diversity in Breast Tumor Metastases
Authors: Almendro Vanessa , Kim Hee Jung , Cheng Yu-Kang , Gönen Mithat , Itzkovitz Shalev , Argani Pedram , van Oudenaarden Alexander , Sukumar Saraswati , Michor Franziska , Polyak Kornelia
Published: March 2023

XLSX file - 9K, Different inference of diversity depending on the loci analyzed.
Supplementary Table 3 from Genetic and Phenotypic Diversity in Breast Tumor Metastases
Authors: Almendro Vanessa , Kim Hee Jung , Cheng Yu-Kang , Gönen Mithat , Itzkovitz Shalev , Argani Pedram , van Oudenaarden Alexander , Sukumar Saraswati , Michor Franziska , Polyak Kornelia
Published: March 2023

XLSX file - 32K, Shannon and Simpson's index for each tumor and each probe based on BAC, CEP, BAC/CEP and unique counts.
Supplementary Table 2 from Genetic and Phenotypic Diversity in Breast Tumor Metastases
Authors: Almendro Vanessa , Kim Hee Jung , Cheng Yu-Kang , Gönen Mithat , Itzkovitz Shalev , Argani Pedram , van Oudenaarden Alexander , Sukumar Saraswati , Michor Franziska , Polyak Kornelia
Published: March 2023

XLSX file - 1151K, BAC and CEP counts for each cell phenotype in the paired metastatic tumor (left) and paired primary and lymph node metastasis (right) series.
Data Supplement from TIGAR Has a Dual Role in Cancer Cell Survival through Regulating Apoptosis and Autophagy
Authors: Xie Jia-Ming , Li Bin , Yu Hong-Pei , Gao Quan-Geng , Li Wei , Wu Hao-Rong , Qin Zheng-Hong
Published: March 2023

Supplemental Figure S1. Epirubicin inhibited cell viability and induced TIGAR expression in A549 cells.
Data Supplement from TIGAR Has a Dual Role in Cancer Cell Survival through Regulating Apoptosis and Autophagy
Authors: Xie Jia-Ming , Li Bin , Yu Hong-Pei , Gao Quan-Geng , Li Wei , Wu Hao-Rong , Qin Zheng-Hong
Published: March 2023

Supplemental Figure S3. Down-regulation of TIGAR inhibited cell survival and enhanced epirubicin-induced apoptosis in A549 cells.