bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise dos perfis físico-químico, microbiológico e organoléptico de cervejas artesanais e industrial do tipo Pilsen comercializadas na Região Metropolitana de Belém-PA
Authors: Souza Bárbara Cristine Queiroz de , Oliveira Karoline Alencar de , Machado Meile Silva , Rivera Juan Gonzalo Bardalez , Oliveira Nayara Cristina Lima de , Quemel Gleicy Kelly China
Published: August 2023

Produzidas de forma industrial ou artesanal as cervejas, normalmente, são compostas por água, lúpulo e malte, podendo apresentar outros ingredientes em sua receita como o trigo, o arroz ou o milho. No Brasil, as cervejas são em sua maioria de produção industrial, porém as cervejas artesanais vêm ganhando destaque no mercado por suas diferentes cores, modos de produção, teores alcoólicos e sabores. Este trabalho teve como objetivo analisar as características físico-químicas, as microbiológicas e as organolépticas de três cervejas, sendo uma industrial e duas artesanais do tipo Pilsen, comercializadas na Região Metropolitana de Belém-PA. Os resultados das análises físico-químicas deram satisfatórios para todas as análises. As análises organolépticas apresentaram um padrão de aceitação conforme o preconizado pela literatura ou legislação, assim como as análises microbiológicas que apresentaram ausência de salmonella, de bactérias, de bolores e de leveduras. Dessa forma, observa-se a importância dos controles de qualidade físico-químicos, microbiológicos e organolépticos, em vista da carência de dados para cervejas artesanais no Brasil.
Pessoas que vivem com HIV/AIDS: uma análise dos fatores associados à não adesão ao tratamento antirretroviral em um Hospital Universitário
Authors: Dias Luana Laiza Porto , Araújo Maria Helena de , Carvalho Ana Márcia Agra Lemos de , Mesquita Andrea Pacheco
Published: August 2023

Este estudo teve como objetivo analisar os motivos para não adesão ao tratamento antirretroviral entre pacientes acompanhados no Hospital Universitário Professor Alberto Antunes – Universidade Federal de Alagoas. Estudo transversal descritivo realizado através de entrevista semiestruturada aplicada aos 15 primeiros usuários acompanhados no Serviço Ambulatorial Especializado com história de não adesão que retornaram no período de janeiro a maio de 2023. Os resultados evidenciaram predomínio da faixa etária de 20 a 39 anos (73,3%), sexo masculino (60%); quanto à orientação sexual, 40% declararam-se heterossexuais, 40% homossexuais e 20% bissexuais; 100% eram pardos ou negros; 60% solteiros, 26,7% casados, 13,3% em união estável; 60% residiam no interior. Apenas 20% trabalhavam, somente 1 entrevistado recebia acima de 1 salário mínimo; 33,3% possuíam ensino médio completo e nenhum possuía ensino superior. O tempo de início do tratamento antirretroviral de menos de 6 meses, 6 meses a 5 anos, 6 a 10 anos e mais de 10 anos, foi observado, respectivamente, em 13,3%, 33,3%, 33,3% e 20% dos entrevistados. Motivos para falha na adesão: depressão (46,7%), falta de motivação (13,3%), dificuldade de acesso por residir em município distante (20%) efeitos adversos (13,3%) e etilismo (6,7%). Diante dos resultados, constata-se que os aspectos relacionados à saúde mental de pessoas que vivem com HIV/AIDS, especialmente depressão, influenciam de modo importante na não adesão ao tratamento. A organização do serviço e o modelo de assistência são de fundamental importância para garantia do acesso e adequada abordagem a intercorrências, com resolução de dificuldades que interfiram na adesão.
Estado e pessoa com deficiência: Uma análise do dever do estado em promover o acesso das pessoas com deficiência às tecnologias assistivas por meio da extrafiscalidade
Authors: Silva Jose André Veríssimo da , Souza Renata Gonçalves de , Souza Darlene Socorro Oliveira de , Costa Talitha Giovanna Maranhão da
Published: August 2023

O presente artigo tem por objetivo analisar o dever do Estado de implementar políticas públicas de cunho extrafiscal direcionadas às pessoas com deficiência objetivando promover o acesso às tecnologias assistivas. Para tanto, utilizou da metodologia de revisão bibliográfica narrativa para analisar o conceito de “pessoa com deficiência”, bem como as leis que beneficiam estas pessoas. Inicialmente, explorou-se a construção do conceito de pessoa com deficiência, apresentando do termo mais arcaico ao mais acertado, que é o utilizado atualmente. Após a conceituação, a pesquisa adentrou a área tributária trabalhando a ideia de tributos, assim como das suas funções, quais sejam: fiscalidade e extrafiscalidade, esta última sendo usada como fio condutor para a efetivação da política pública do acesso às tecnologias assistivas. Ademais, foi discutida a promoção dos direitos fundamentais das pessoas com deficiência por meio de políticas extrafiscais. Por fim, nas considerações finais verificou-se que o Estado deve aplicar políticas públicas de cunho extrafiscal, pois o acesso das pessoas com deficiência às tecnologias assistivas concretiza o princípio da isonomia, efetivando a igualdade no campo material.
O conhecimento matemático na perspectiva do professor de matemática para a formação crítica do sujeito
Authors: Nóbrega Maria Rafaela Andrade da , Barboza Pedro Lúcio
Published: August 2023

Este artigo tem como objetivo verificar as concepções dos professores de matemática da Educação Básica sobre a formalização e relação do conhecimento matemático com as outras disciplinas e o contexto social. A pesquisa de cunho qualitativa, foi realizada em campo, utilizando a entrevista como instrumento para coletar as concepções de dez (10) professores de matemática dos Anos Finais e Ensino Médio de escolas públicas e privadas da Paraíba. Após os dados obtidos, foram feitas as transcrições para as devidas análises e discussão teórica com base na análise de conteúdo de Bardin. Com os resultados, percebemos que os questionamentos realizados aos professores da pesquisa sobre o conhecimento matemático, oportunizaram momentos de reflexão, pois alguns tiveram dificuldades de relacionar a matemática com outros contextos. Os docentes devem seguir em um processo contínuo de reflexão e ação, a fim de consolidar ou alterar percepções que influenciam nas ações diárias e na prática pedagógica realizada em sala. A formação continuada é fundamental para sanar as lacunas da formação inicial do professor e aprimorar os conhecimentos específicos e pedagógicos, oferecendo aos estudantes a construção do conhecimento matemático que transpasse a dimensão cognitiva e prepare o aluno para atuar, de forma crítica, consciente, autônoma e democrática na sociedade.
Atuação farmacêutica em práticas integrativas: Uma revisão
Authors: Nunes Weldieni Martins Pereira , Santos Jânio Sousa
Published: August 2023

As Práticas Integrativas e Complementares em Saúde estimulam o trabalho multiprofissional, acolhendo o farmacêutico pelas suas atribuições clínicas. Desta forma o objetivo do presente estudo foi apresentar por meio de uma revisão da literatura a atuação do profissional farmacêutico frente as práticas integrativas e complementares. O presente estudo trata-se de uma revisão narrativa da literatura Na qual foi empregada buscas nas bibliográficas nacionais e internacionais. Tal revisão apresenta uma abordagem qualitativa de natureza básica com o objetivo exploratório. As buscas foram realizadas em bases de dados como: LILACS, MedLINE  e SciELO. As Práticas Integrativas e Complementares – PICs, são terapias que estimulam os mecanismos do organismo para prevenção e recuperação da saúde, decorrente de tecnologias eficazes e seguras. Dentre os profissionais da saúde qualificado para atuar nessas práticas, estão os farmacêuticos. O papel do farmacêutico amplia-se para os serviços de orientação e em medidas de suporte para a terapêutica, cooperando para o bem-estar do indivíduo e, consequentemente, impedir diversas enfermidades, como as doenças crônicas e contribuindo assim para o autocuidado, promoção e conservação da saúde. A revisão mostrou que o farmacêutico tem um papel fundamental na integração dessas práticas ao contexto clínico, participando de diversas etapas, desde a seleção de fitoterápicos por exemplo, até a orientação e acompanhamento do paciente. Por meio de uma visão holística, o farmacêutico pode avaliar a interação entre as terapias convencionais e integrativas, contribuindo para uma abordagem mais abrangente e personalizada ao cuidado do paciente.
A relação entre o ácido hialurônico e a COVID-19: uma revisão narrativa da literatura
Authors: Lopes Natiely Viana , Suguihara Roberto Teruo , Muknicka Daniella Pilon
Published: August 2023

Preenchimentos dérmicos com ácido hialurônico são uma escolha popular para melhorar a aparência estética com baixo risco de reações inflamatórias tardias. No entanto, relatos de reações de hipersensibilidade tardia após a vacinação COVID-19 levantaram preocupações. Embora a vacinação seja fundamental para combater a pandemia, os profissionais devem obter consentimento informado dos pacientes sobre possíveis interações com preenchimentos dérmicos e riscos de síndrome de hipersensibilidade tardia. Embora raras, essas reações requerem atenção e preparação dos profissionais para gerenciamento adequado, garantindo a segurança dos pacientes. O estudo que relaciona a vacinação, harmonização orofacial e preenchedores dérmicos com edema tardio intermitente persistente é clinicamente relevante, destacando a necessidade de compreender as interações e prevenir complicações em meio à ampla adoção da vacinação contra a COVID-19. Essa revisão narrativa da literatura tem como objetivo servir de base para o maior entendimento entre a relação da COVID-19, preenchedores dérmicos a base de ácido hialurônico e o edema tardio intermitente persistente.
ANALISIS METODE DAKWAH USTADZ ABDUL SOMAD DI MEDIA SOSIAL (STUDI KASUS CHANEL YOUTUBE USTADZ ABDUL SOMAD OFFICIAL EDISI JANUARI-MARET 2021)
Authors: Nur Ramdhan Ashraf , Asâ€™ad Muhammad
Published: August 2023

Ustaz Abdul Somad adalah seorang da'i yang sukses dalam menyampaikan dakwahnya di berbagai daerah bahkan negara. Dengan penyampaiannya Ustadz Abdus Shomad dapat memberikan pemahaman yang baik terhadap masyarakat. Begitu besar pengaruh dakwah yang disampaikan oleh Ustaz Abdul Somad dengan gaya dakwah dan retorikanya yang khas, penulis tertarik untuk mengkaji pengaruh dan metode yang digunakannya. Penelitian ini difokuskan pada dakwah Ustaz Abdul Somad pada bulan Januari-Maret 2021, fokus masalah diarahkan pada metode dakwah, retorika dakwah dan channel youtube Ustaz Abdul Somad. Hal ini berdasarkan jumlah followers channel youtube Ustaz Abdul Somad. Penelitian ini menggunakan penelitian kualitatif dengan teknik pengumpulan data yaitu dengan cara observasi online download video dakwah Ustaz Abdul Somad. Dari hasil penelitian ini ditemukan bahwa metode dakwah yang digunakan oleh Ustaz Abdul Somad dikategorikan menjadi 3 metode, yaitu: metode hikmah, Al-Mauidzah al-Hasanah dan Al-mujdalam al-ahsan. Gaya retorika yang digunakan oleh Ustaz Abdul Somad juga terbagi menjadi 3 jenis, yaitu: monologis, dialogis dan pembinaan. Kemudian dalam perkembangan Akun Youtube Ustaz Abdul Somad pada Januari â€“ Maret 2021, akun Youtube @Usatdz Abdul Somad Official memiliki 2,03 juta subscriber dan rata-rata 90 ribu views. Diharapkan penelitian ini dapat dikaji dan diteliti lebih dalam oleh peneliti lain, baik dengan metode maupun objek penelitian lain.
ANALISIS FRAMING PEMBERITAAN ISU PENCABULAN SANTRIWATI DI SERANG BANTEN PADA KOMPAS.COM DAN TRIBUNBANTEN.COM
Authors: Haryanti Nanda Kumala , Anwari
Published: August 2023

This study focuses on two issues: firstly, how Kompas.com conducts the framing of news regarding the case of three female Islamic boarding school students' molestation in Kasemen District, Serang City, Banten, on December 12, 2022, and secondly, the comparison of news framing regarding the same molestation case between Kompas.com and TribunBanten.com on December 12, 2022. To address these two issues, the researcher utilizes a qualitative approach. The method employed by the researcher is the framing analysis method developed by Robert N. Entman in the study entitled “Framing the Issue of Female Islamic Boarding School Students' Molestation in the Online Media of Kompas.com and TribunBanten.com on December 12, 2022. The findings of this study lead to the conclusion that Kompas.com and TribunBanten.com exhibit distinct textual structures. Particularly on Kompas.com, there is a discernible tendency to side with the victims and firmly incriminate the perpetrators. On the other hand, the textual structure of news regarding the issue of Female Islamic Boarding School Students' Molestation on TribunBanten.com demonstrates a lack of clarity in delineating the chronology of events. Moreover, the discourse accentuates the notion that the conduct undertaken by the perpetrators is inherently unacceptable and should not have transpired.
Partisan Media as a Bridge between Elite Cues and Public Attitude: During the COVID-19 Pandemic in South Korea
Authors: Lee Hoeun
Published: August 2023

Levels of public polarization in evaluations of government responses to COVID-19 and perceptions of COVID-19 severity exhibit varying degrees across countries worldwide. This study aims to examine whether these disparities can be attributed to variations in elite messaging concerning COVID-19, as conveyed through the media. Through text mining of South Korean newspapers, we observe a convergence of media and elite discourse on the gravity of COVID-19 while divergent viewpoints emerge regarding government performance. In this scenario, we would expect that public opinion did so as well. Our findings suggest that the degree of polarization in public attitudes toward COVID-19 is largely contingent upon the extent to which the pandemic is partisan-framed by political elites and subsequently communicated to the populace through media channels.
The influence of over-distraction on biomechanical response of cervical spine post anterior interbody fusion: a comprehensive finite element study
Authors: Cheng Chih-Hsiu , Chiu Ping-Yeh , Chen Hung-Bin , Niu Chi-Chien , Nikkhoo Mohammad
Published: August 2023

Introduction: Anterior cervical discectomy and fusion (ACDF) has been considered as the gold standard surgical treatment for cervical degenerative pathologies. Some surgeons tend to use larger-sized interbody cages during ACDF to restore the index intervertebral disc height, hence, this study evaluated the effect of larger-sized interbody cages on the cervical spine with ACDF under both static and cyclic loading.

Method: Twenty pre-operative personalized poro-hyperelastic finite element (FE) models were developed. ACDF post-operative models were then constructed and four clinical scenarios (i.e., 1) No-distraction; 2) 1 mm distraction; 3) 2 mm distraction; and 4) 3 mm distraction) were predicted for each patient. The biomechanical responses at adjacent spinal levels were studied subject to static and cyclic loading. Non-parametric Friedman statistical comparative tests were performed and the p values less than 0.05 were reflected as significant.

Results: The calculated intersegmental range of motion (ROM) and intradiscal pressure (IDP) from 20 pre-operative FE models were within the overall ranges compared to the available data from literature. Under static loading, greater ROM, IDP, facet joint force (FJF) values were detected post ACDF, as compared with pre-op. Over-distraction induced significantly higher IDP and FJF in both upper and lower adjacent levels in extension. Higher annulus fibrosus stress and strain values, and increased disc height and fluid loss at the adjacent levels were observed in ACDF group which significantly increased for over-distraction groups.

Discussion: it was concluded that using larger-sized interbody cages (the height of ≥2 mm of the index disc height) can result in remarkable variations in biomechanical responses of adjacent levels, which may indicate as risk factor for adjacent segment disease. The results of this comprehensive FE investigation using personalized modeling technique highlight the importance of selecting the appropriate height of interbody cage in ACDF surgery.
Neuroprotection from protein misfolding in cerebral hypoperfusion concurrent with metabolic syndrome. A translational perspective
Authors: Bordet Sofía , Luaces Juan Pablo , Herrera Maria Ines , Gonzalez Liliana Mirta , Kobiec Tamara , Perez-Lloret Santiago , Otero-Losada Matilde , Capani Francisco
Published: August 2023

Based on clinical and experimental evidence, metabolic syndrome (MetS) and type 2 diabetes (T2D) are considered risk factors for chronic cerebral hypoperfusion (CCH) and neurodegeneration. Scientific evidence suggests that protein misfolding is a potential mechanism that explains how CCH can lead to either Alzheimer’s disease (AD) or vascular cognitive impairment and dementia (VCID). Over the last decade, there has been a significant increase in the number of experimental studies regarding this issue. Using several animal paradigms and different markers of CCH, scientists have discussed the extent to which MetSor T2D causes a decrease in cerebral blood flow (CBF). In addition, different models of CCH have explored how long-term reductions in oxygen and energy supply can trigger AD or VCID via protein misfolding and aggregation. Research that combines two or three animal models could broaden knowledge of the links between these pathological conditions. Recent experimental studies suggest novel neuroprotective properties of protein-remodeling factors. In this review, we present a summarized updated revision of preclinical findings, discussing clinical implications and proposing new experimental approaches from a translational perspective. We are confident that research studies, both clinical and experimental, may find new diagnostic and therapeutic tools to prevent neurodegeneration associated with MetS, diabetes, and any other chronic non-communicable disease (NCD) associated with diet and lifestyle risk factors.
2.79-μm high peak power LiNbO3 acousto-optic Q-switched Er,Cr:YSGG laser with thermal lensing effect compensation
Authors: Jiang Lingling , Wu Zhongchao , Ma Shengjie , Zhu Yongbin , Cheng Tingqing , Jiang Haihe
Published: August 2023

A new type of lithium niobate (LiNbO3) acousto-optic Q-switched Er,Cr:YSGG laser with high peak power was designed and the thermal lensing effect compensation was studied. The values of thermal focal length in the gain medium were calculated theoretically and measured experimentally. The experimental results validate the designed plane-convex resonator validity, and the output performance of the 2.79 μm Er,Cr:YSGG laser was obviously improved. When the laser operated at free running region, the maximum values of pulse energy was 160 mJ at 60 Hz, compared with the plane-parallel resonator, the pulse energy was increased by 2 times in the plane-convex resonator. When the LiNbO3 Q-switched laser operated at 60 Hz, the maximum values of pulse energy was 8.5 mJ, and the minimum values of pulse duration was 60.8 ns, and the corresponding peak power approximately was 140 kW, respectively. Compared with the plane-parallel resonator, the pulse energy was increased by 1.6 times in the plane-convex resonator, the corresponding peak power was increased by 2.3 times.
Effects of clonal integration and nutrient availability on the growth of Glechoma longituba under heterogenous light conditions
Authors: Zhang Rui , Chen Zhi-Huan , Li Yu-Meng , Wang Ning , Cui Wen-Tao , Zhao Bing-Nan , Si Chao
Published: August 2023

Introduction

Clonal integration of connected ramets within clones is an important ecological advantage. In this study, we tested the hypothesis that the effects of clonal integration on performance of donor and recipient ramets when one resource is heterogeneous can be influenced by the availability of another resource of donor ramets.

Methods

We conducted a greenhouse experiment on the widespread, perennial herb Glechoma longituba. Clonal fragments consisting of pairs of connected ramets were grown for seven weeks. The younger, apical ramets were exposed under 30% or 100% light condition and the older, basal ramets were treated with three levels of nutrients. The connections between ramets were either severed or left intact. 30% light condition negatively affected the growth of apical ramets, basal ramets and the whole fragments.

Results

Clonal integration significantly increased the growth of apical ramets, but decreased the growth of the basal ramets. Medium and high level nutrient availability of basal ramets significantly increased the growth of apical ramets, basal ramets and the whole fragments. At the high nutrient level, the reduction in growth of basal ramets from clonal integration was decreased, but the growth responses of apical ramets and the whole fragments to clonal integration were not influenced by nutrient availability.

Conclusion

The results suggested that clonal integration was benefit to the growth of apical ramets of Glechoma longituba but at the cost of reducing the growth of basal ramets. Although the high nutrient level could reduce the cost that clonal integration brought to the unshaded basal ramets, but could not increase the benefit that clonal integration brought to the shaded apical ramets and whole fragment.
Perceptions of the motivational climate, basic psychological needs, and life skills development in Chinese physical education students
Authors: Zheng Shaofeng , Ji Xiangbo , Cheng Liping , Xu Jianhua , Cronin Lorcan Donal
Published: August 2023

Introduction

Life skills can have a positive impact on young people’s mental health, academic performance, and overall well-being. Physical education (PE) is viewed as a promising setting for developing students’ life skills, but less is known about this in non-English speaking countries such as China. Based on the integration of Self-Determination Theory (SDT) and Achievement Goal Theory (AGT), we aimed to examine the relationships between students’ perceptions of the teacher-initiated motivational climate (mastery- or performance-oriented) and their life skills development in PE, as well as the mediating role of their basic psychological needs (BPNs) (satisfaction or frustration).

Methods

We employed a cross-sectional survey. Chinese students (N = 533, Age range = 13–18 years) completed measures assessing these variables. We fulfilled correlational and mediational analyses.

Results

These findings showed that mastery climate was positively associated with needs satisfaction (r = 0.66) and eight life skills (r range = 0.44–0.61), whereas negatively associated with needs frustration (r = −0.49). Performance climate was positively related to needs frustration (r = 0.52), but negatively related to needs satisfaction (r = −0.38) and eight life skills (r range = −0.28 – −0.15). Needs satisfaction was positively (r range = 0.44–0.65), while needs frustration was negatively (r range = −0.50 – −0.34) linked with eight life skills. Furthermore, needs satisfaction positively mediated the effect of mastery climate on life skills development, but it is not found that needs frustration mediated the effect of performance climate on life skills besides goal setting, social skills, and time management.

Conclusion

In conclusion, our study extended the previous literature on life skills in PE, and highlighted the roles of motivational climate and BPNs on students’ life skills development. In practice, PE teachers should be encouraged to create a mastery climate as well as avoid a performance climate, to foster students’ BPNs satisfaction, which in turn, promote their life skills development.
Evaluation of an Arabic Chatbot Based on Extractive Question-Answering Transfer Learning and Language Transformers
Authors: Alruqi Tahani N. , Alzahrani Salha M.
Published: August 2023

Chatbots are programs with the ability to understand and respond to natural language in a way that is both informative and engaging. This study explored the current trends of using transformers and transfer learning techniques on Arabic chatbots. The proposed methods used various transformers and semantic embedding models from AraBERT, CAMeLBERT, AraElectra-SQuAD, and AraElectra (Generator/Discriminator). Two datasets were used for the evaluation: one with 398 questions, and the other with 1395 questions and 365,568 documents sourced from Arabic Wikipedia. Extensive experimental works were conducted, evaluating both manually crafted questions and the entire set of questions by using confidence and similarity metrics. Our experimental results demonstrate that combining the power of transformer architecture with extractive chatbots can provide more accurate and contextually relevant answers to questions in Arabic. Specifically, our experimental results showed that the AraElectra-SQuAD model consistently outperformed other models. It achieved an average confidence score of 0.6422 and an average similarity score of 0.9773 on the first dataset, and an average confidence score of 0.6658 and similarity score of 0.9660 on the second dataset. The study concludes that the AraElectra-SQuAD showed remarkable performance, high confidence, and robustness, which highlights its potential for practical applications in natural language processing tasks for Arabic chatbots. The study suggests that the language transformers can be further enhanced and used for various tasks, such as specialized chatbots, virtual assistants, and information retrieval systems for Arabic-speaking users.
Inelastic Behavior of Steel and Composite Frame Structure Subjected to Earthquake Loading
Authors: Gajbhiye P. D. , Mashaan Nuha S. , Bhaiya V. , Wankhade Rajan L. , Vishnu S. P.
Published: August 2023

Steel construction is used more often these days as an alternative to the R.C.C. when lightweight, high-strength, large-span structures with a faster erection are required. Extensive studies have been conducted by researchers to study the seismic performance of reinforced concrete and steel structures, both in terms of elastic and inelastic behavior. Composite construction is also a recent advancement in the building industry with similar advantages. However, no emphasis has been given to the comparison between the inelastic behavior of steel and composite structures when subjected to lateral loads. This study compares the inelastic behavior of steel and a composite frame designed to have the same plastic moment capacity for structural members. The responses, such as the formation of hinges, story drifts, story displacements, lateral stiffness, ductility, maximum strength, energy dissipated, joint accelerations, and performance points, are compared with the aid of the building analysis and design software ETABS-18. For this, response spectrum analysis, pushover analysis, and nonlinear direct integration time history analysis have been performed on both frames. For design and analysis, international codes, such as IS 800-2007, IS 875 (Part I, II, IV), IS 1893-2002, AISC 360 (16 and 10), and FEMA 440, have been used. Part of this study also aims at comparing the response of these frames when subjected to near-field and far-field earthquakes. It can be concluded from the results that the post-yield performance of the composite frame is superior to that of the steel frame when seismically excited.
Differential Expression of Subsets of Genes Related to HDL Metabolism and Atherogenesis in the Peripheral Blood in Coronary Artery Disease
Authors: Dergunov Alexander D. , Nosova Elena V. , Rozhkova Alexandra V. , Vinogradina Margarita A. , Baserova Veronika B. , Popov Mikhail A. , Limborska Svetlana A. , Dergunova Liudmila V.
Published: August 2023

Differential expression of genes (DEGs) in coronary artery disease (CAD) and the association between transcript level and high-density lipoprotein cholesterol (HDL-C) were studied with 76 male patients with CAD and 63 control patients. The transcript level of genes related to HDL metabolism (24 genes) and atherosclerosis-prone (41 genes) in RNA isolated from peripheral blood mononuclear cells was measured by real-time RT-PCR. Twenty-eight DEGs were identified. The expression of cholesterol transporters, ALB, APOA1, and LCAT was down-regulated, while the expression of AMN, APOE, LDLR, LPL, PLTP, PRKACA, and CETP was up-regulated. The systemic inflammation in CAD is evidenced by the up-regulation of IL1B, TLR8, CXCL5, and TNFRSF1A. For the controls, TLR8 and SOAT1 were negative predictors of the HDL-C level. For CAD patients, PRKACG, PRKCQ, and SREBF1 were positive predictors, while PRKACB, LCAT, and S100A8 were negative predictors. For CAD patients, the efficiency of reverse cholesterol transport is 73–79%, and intracellular free cholesterol seems to accumulate at hyperalphalipoproteinemia. Both atheroprotective (via S100A8) and proatherogenic (via SREBF1, LCAT, PRKACG, PRKACB, and PRKCQ) associations of gene expression with HDL-C determine HDL functionality in CAD patients. The selected key genes and involved pathways may represent HDL-specific targets for the diagnosis and treatment of CAD and atherosclerosis.
ab Initio DFT and MD Simulations Serving as an Anchor for Correcting Melting Curves Reported by DAC and SW Experiments—Some Transition Metals as Illustrative Examples
Authors: Gal Joseph
Published: August 2023

The pressure–temperature scales in DAC and shock wave (SW) experiments should be corrected by taking into account the thermal pressure shifts. In the present contribution, it is further claimed that first-principle ab initio DFT and MD simulations should serve as an anchor for correcting the pressures and temperatures reported by DAC and SW experiments. It was concluded that upon deriving the actual pressure sensed by the explored sample, the thermal pressure and the temperature shifts must be taken into account when constructing melting curves. Therefore, melting curves measured by diamond anvil cells for 3d elements do not contribute to a better understanding of the geophysical Earth’s inner core. In addition, the advantage of the Lindemann–Gilvarry vs. Simon–Glatzel fitting procedure of melting curves is shown.
Assessment of the Formation of the Economic Effect of Cross-Subsidization in the Electric Power Industry
Authors: Leschinskaya Aleksandra , Kirillova Oksana , Palyanov Maksim
Published: August 2023

The materials presented in the article reflect changes in the mechanism of cross-subsidization in the electric power industry, where price discrimination of consumers has taken place until recently. Historically, the established practice has been expressed in the redistribution of the burden of paying for electric energy between consumer groups, ensuring the containment of tariff growth. However, the reduction of tariffs for some categories of citizens was achieved by increasing them for others, social justice was violated and, for some buyers, the price is set above marginal costs, and for others—lower, although, in general, it led to prices corresponding to average costs. This policy was considered by the state as a measure of social support for the population but, at the same time, led to some negative consequences. The presented conceptual provisions for the creation of unified energy zones aimed at ensuring a fair redistribution of cross-subsidization between electricity consumers and a gradual reduction in its consumption will make it possible to form a unified energy space of Russia. On a concrete example, the socio-economic effects of the introduction of the author’s approach to the distribution of cross-subsidization between groups of consumers of electric power transmission services are identified and shown. They show the degree of influence of the amount of cross-subsidization paid by the consumer company on the cost of the final products that this company produces. The price of electric energy, which is part of the cost of production, significantly changes the consumer cost of energy-intensive production. The implementation of the proposals contained in the article will create economic incentives for the development of economically lagging regions and will make it possible to form an effective state tariff policy in the process of regulating the socio-economic development of the Russian Federation, defining an effective state tariff policy.
Effects of P:Ni Ratio on Methanol Steam Reforming on Nickel Phosphide Catalysts
Authors: Almithn Abdulrahman
Published: August 2023

This study investigates the influence of the phosphorus-to-nickel (P:Ni) ratio on methanol steam reforming (MSR) over nickel phosphide catalysts using density functional theory (DFT) calculations. The catalytic behavior of Ni(111) and Ni12P5(001) surfaces was explored and contrasted to our previous results from research on Ni2P(001). The DFT-predicted barriers reveal that Ni(111) predominantly favors the methanol decomposition route, where methanol is converted into carbon monoxide through a stepwise pathway involving CH3OH* → CH3O* → CH2O* → CHO* → CO*. On the other hand, Ni12P5 with a P:Ni atomic ratio of 0.42 (5:12) exhibits a substantial increase in selectivity towards methanol steam reforming (MSR) relative to methanol decomposition. In this pathway, formaldehyde is transformed into CO2 through a sequence of reactions involving CH2O*→ H2COOH* → HCOOH* → HCOO* → CO2. The introduction of phosphorus into the catalyst alters the surface morphology and electronic structure, favoring the MSR pathway. However, with a further increase in the P:Ni atomic ratio to 0.5 (1:2) on Ni2P catalysts, the selectivity towards MSR decreases, resulting in a more balanced competition between methanol decomposition and MSR. These results highlight the significance of tuning the P:Ni atomic ratio in designing efficient catalysts for the selective production of CO2 through the MSR route, offering valuable insights into optimizing nickel phosphide catalysts for desired chemical transformations.
Synthesis of Ag3PO4/Ag/g-C3N4 Composite for Enhanced Photocatalytic Degradation of Methyl Orange
Authors: Liu Qingwang , Meng Ying , Liu Qiman , Xu Mai , Hu Yunhu , Chen Shikun
Published: August 2023

In this study, we have successfully constructed Ag3PO4/Ag/g-C3N4 heterojunctions via the hydrothermal method, which displays a wide photo-absorption range. The higher photocurrent intensity of Ag3PO4/Ag/g-C3N4 indicates that the separation efficiency of the photogenerated electron–hole pairs is higher than that of both Ag3PO4 and Ag/g-C3N4 pure substances. It is confirmed that the efficient separation of photogenerated electron–hole pairs is attributed to the heterojunction of the material. Under visible light irradiation, Ag3PO4/Ag/g-C3N4-1.6 can remove MO (~90%) at a higher rate than Ag3PO4 or Ag/g-C3N4. Its degradation rate is 0.04126 min−1, which is 4.23 and 6.53 times that of Ag/g-C3N4 and Ag3PO4, respectively. After five cycles of testing, the Ag3PO4/Ag/g-C3N4 photocatalyst still maintained high photocatalytic activity. The excellent photocatalysis of Ag3PO4/Ag/g-C3N4-1.6 under ultraviolet-visible light is due to the efficient separation of photogenerated carriers brought about by the construction of the Ag3PO4/Ag/g-C3N4 heterostructure. Additionally, Ag3PO4/Ag/g-C3N4 specimens can be easily recycled with high stability. The effects of hydroxyl and superoxide radicals on the degradation process of organic compounds were studied using electron paramagnetic resonance spectroscopy and radical quenching experiments. Therefore, the Ag3PO4/Ag/g-C3N4 composite can be used as an efficient and recyclable UV-vis spectrum-driven photocatalyst for the purification of organic pollutants.
In Situ Low-Temperature Carbonization Capping of LiFePO4 with Coke for Enhanced Lithium Battery Performance
Authors: Guo Fei , Huang Xiaoqi , Li Yudong , Zhang Shaohui , He Xiong , Liu Jinghua , Yu Zhiqiang , Li Feng , Liu Baosheng
Published: August 2023

Lithium batteries incorporating LiFePO4 (LFP) as the cathode material have gained significant attention in recent research. However, the limited electronic and ionic conductivity of LFP poses challenges to its cycling performance and overall efficiency. In this study, we address these issues by synthesizing a series of LiFePO4/carbon (LFP/C) composites through low-temperature carbonization coating of LFP in the presence of Coke as the carbon source. The resulting lithium batteries utilizing LFP/C as the cathode material exhibited impressive discharge specific capacities of 148.35 mA·h/g and 126.74 mA·h/g at 0.1 C and 1 C rates, respectively. Even after 200 cycles of charging and discharging, the capacities remained remarkably high, with values of 93.74% and 97.05% retention, showcasing excellent cycling stability. Notably, the LFP/C composite displayed exceptional rate capability, and capacity retention of 99.27% after cycling at different multiplication rates. These findings underscore the efficacy of in situ low-temperature carbonization capping of LFP with Coke in significantly improving both the cycling stability and rate capability of lithium batteries.
Chemical Studies of Multicomponent Kidney Stones Using the Modern Advanced Research Methods
Authors: Sofińska-Chmiel Weronika , Goliszek Marta , Drewniak Marek , Nowicka Aldona , Kuśmierz Marcin , Adamczuk Agnieszka , Malinowska Paulina , Maciejewski Ryszard , Tatarczak-Michalewska Małgorzata , Blicharska Eliza
Published: August 2023

Defining the kidney stone composition is important for determining a treatment plan, understanding etiology and preventing recurrence of nephrolithiasis, which is considered as a common, civilization disease and a serious worldwide medical problem. The aim of this study was to investigate the morphology and chemical composition of multicomponent kidney stones. The identification methods such as infrared spectroscopy (FTIR), X-ray diffraction (XRD), and electron microscopy with the EDX detector were presented. The studies by the X-ray photoelectron spectroscopy (XPS) were also carried out for better understanding of their chemical structure. The chemical mapping by the FTIR microscopy was performed to show the distribution of individual chemical compounds that constitute the building blocks of kidney stones. The use of modern research methods with a particular emphasis on the spectroscopic methods allowed for a thorough examination of the subject of nephrolithiasis.
Exploring the Impact of COVID-19 and the Associated Lockdown on the Production, Distribution, and Consumption of Poultry Products in Gujarat, India: A Qualitative Study
Authors: Mishra Pallavi , Golaviya Akash , Panchal Ketankumar , Hinsu Ankit , Yadav Kavita , Fournié Guillaume , Barnett Tony , Koringa Prakash , Paleja Haidar Ul Iman , Dasgupta Rajib
Published: August 2023

Background: The poultry industry in India, estimated to be worth about one trillion INR, was severely affected by the COVID-19 pandemic. This study was conducted in Gujarat, India to unpack the processes through which COVID-19-related factors affected the poultry production and distribution network and explore the impacts on the relevant actors. Methods: An exploratory qualitative study was conducted among 34 poultry stakeholders using semi-structured interviews. The data were thematically analyzed by adopting an interpretative phenomenological approach. Results: Convincing evidence emerged that the lockdown and the pandemic significantly impacted the production, distribution, and consumption of poultry products. Movement restrictions during the first lockdown disrupted the supply of inputs and the distribution of poultry and poultry products. Between March and June 2020, rumors contributed to a substantial decrease in the consumption of poultry products. Consumption picked up following the reopening after the lockdown and the prices and availability of poultry products. The profits, however, failed to compensate for the losses that had been incurred. Conclusions: The experience and impacts of the first COVID-19 lockdown on the poultry industry unraveled several short- and medium-term challenges in the poultry sector in India that need to be addressed to make it more resilient to similar shocks.
Design and Implementation of a Versatile OpenHAB IoT Testbed with a Variety of Wireless Interfaces and Sensors
Authors: Tsakalidis Sotirios , Tsoulos George , Kontaxis Dimitrios , Athanasiadou Georgia
Published: August 2023

This paper presents the design and implementation of a versatile IoT testbed utilizing the openHAB platform, along with various wireless interfaces, including Z-Wave, ZigBee, Wi-Fi, 4G-LTE (Long-Term Evolution), and IR (Infrared Radiation), and an array of sensors for motion, temperature, luminance, humidity, vibration, UV (ultraviolet), and energy consumption. First, the testbed architecture, setup, basic testing, and collected data results are described. Then, by showcasing a typical day in the laboratory, we illustrate the testbed’s potential through the collection and analysis of data from multiple sensors. The study also explores the capabilities of the openHAB platform, including its robust persistence layer, event management, real-time monitoring, and customization. The significance of the testbed in enhancing data collection methodologies for energy assets and unlocking new possibilities in the realm of IoT technologies is particularly highlighted.
APLIKASI PREDIKSI PERSEDIAAN BARANG PADA TOKO GUDANG ACC WONOSOBO DENGAN METODE DOUBLE EXPONENTIAL SMOOTHING BERBASIS WEB
Authors: Sibyan Hidayatus , Dwi Kartika Caesar , Asnawi M. Fuat
Published: August 2023

Banyaknya merk dan jenis yang beragam mempersulit pemilik Toko Gudang Acc dalam memanajemen persediaan barang. Persediaan yang tidak memenuhi permintaan akan mengecewakan konsumen karena pengadaan yang lama serta produk yang tidak laku di tempat persediaan menumpuk karena penjualan yang minimum maupun jenis atau merk barang yang sudah tidak update lagi. Tujuan dari penelitian ini adalah membuat aplikasi toko aksesoris handphone berbasis web yang dapat menentukan prediksi persediaan barang sehingga tidak terjadi penumpukan persediaan barang dengan menggunakan metode Double Exponential Smooting. Dengan menggunakan metode Double Exponential Smoothing menunjukan hasil yang bagus yaitu produk Tempered Glass warna dengan alfa sebesar 0,2 diperoleh nilai prediksi 4.441 pada bulan berikutnya dengan nilai MAPE sebesar 7%, sedangkan produk Tempered Glass bening dengan nilai alfa 0,6 diperoleh nilai prediksi 12.548 pada bulan berikutnya dengan nilai MAPE sebesar 3%. Dari pengujian nilai kesalahan prediksi pada kedua data dengan menggunakan perhitungan Mean Absolute Persentage Error (MAPE) menunjukan hasil yang sangat bagus karena memiliki tingkat error di bawah 10%. Berdasarkan penelitian yang telah dilaksanakan dapat disimpulkan bahwa aplikasi telah berhasil menerapkan metode Double Exponential Smoothing, sehingga dapat membantu dalam menentukan jumlah persediaan pada periode berikutnya agar tidak terjadi penumpukan persediaan barang.
SISTEM INFORMASI MANAJEMEN ASET MENGGUNAKAN METODE DEPRECIATED REPLACEMENT COST DI SATKORDIKCAM JEPARA
Authors: Alfianto Wisnu Prasetyo Muhammad , Azizah Noor , Saputro Heru
Published: August 2023

Learning support equipment is a very important main component in an educational process, because the learning process uses tools to facilitate the educational process. SATKORDIKCAM is this government agency that regulates education in the sub-district area, so in every sub-district there will be a similar institution, because SATKORDIKCAM controls education in the sub-district area it regulates and has various tasks, one of which is in the field of goods management, namely by fostering, supervising and control the state property owned, and must document and manage the goods in their environment. The documentation process which consists of supervising and controlling the goods is a form of management so that the condition of the goods can be known. The status of the goods or conditions in question include the position of the goods, the condition of the goods, the current price of the goods, and the service life of the goods. Submission of web-based information can make it easier to access information on goods anywhere and anytime online. Making it easier for the admin to carry out the asset management process and the calculation of asset depreciation.
SISTEM MONITORING SERVER BERBASIS ANDROID DI DINAS KOMUNIKASI DAN INFORMATIKA KABUPATEN REMBANG
Authors: Rifqi Azizi Moh , Lutfi Septia , Purwanto Agus
Published: August 2023

In this research, identification has been made to make an Android-based server monitoring application using the System Development Life Cycle Technique. This research is based on the work of monitoring servers to find out which servers are down / offline or which servers are up / online.

This research uses descriptive research method. Descriptive research is generally carried out with the aim of systematically describing the facts and characteristics of the object and subject being studied appropriately. The stages carried out in the descriptive model include stages such as analysis, design, implementation, evaluation, improvement, and development.

Based on testing the quality of the software for functionality aspect, the server monitoring information system has fulfilled the overall function with a success percentage of 100%.

Based on the results of software quality testing on the usability aspect, it produces a total score of 893 which is converted into an index scale getting a value of 94%. Then a percentage of 94% is converted into a qualitative scale resulting in a feasible rating scale. So it can be concluded that the server monitoring information system has met the usability aspect.

The result of this research is an android based software which can monitor server. Users can find out which servers are up / online or which servers are down / offline. Users can monitor server conditions in realtime
ADCY5-related dyskinesia: a treatable inherited neurometabolic disorder
Authors: Melo de Almeida Igor , Lopes Braga Vinícius , Braga Farias Igor , Ismael Lacerda Machado Roberta , De Lima Serrano Paulo , De Mattos Lombardi Badia Bruno , Dos Santos Jorge Ana Carolina , Bocca Vieira de Rezende Pinto Wladimir , Sgobbi de Souza Paulo Victor , Souza Bulle Oliveira Acary
Published: August 2023

Case Report. A 40-year-old Brazilian man presented with long-standing loss of balance, dystonia, and choreoathetosis, with episodic paroxysmal worsening. Neuroimaging and cerebrospinal fluid analysis were both unremarkable. Quantitative urine organic acid analysis, plasma acylcarnitine quantitative profile, and quantitative analysis of plasma amino acids by high performance liquid chromatography were all within normal interval values. Multigene next-generation sequencing panel identified the heterozygous pathogenic variant c.1252C>T (p.Arg418Trp) in the ADCY5 gene, defining a diagnosis of ADCY5-related dyskinesia. Oral caffeine was associated to clonazepam and provided marked improvement of motor symptoms. Conclusion. This report adds evidence to the safety and efficacy of caffeine in the treatment of genetically confirmed cases of ADCY5-related dyskinesia in the context of gain-of-function variants.
”Jag söker gemenskap”
Authors: Bremer Signe
Published: August 2023

Mellan åren 1960 och 1970 skrev många personer som företrädelsevis kallade sig transvestiter till de svenska sextidningar Piff och Raff för att be om råd kring frågor om könsidentitet samt för att söka gemenskap. Föreliggande artikel resonerar kring hur detta kom sig. Varför skrev personer med transerfarenheter just hit? Vilka teman är det som lyfts och vilka svar får de av Piff:s och Raff:s redaktioner? Med utgångspunkt i dessa frågor analyseras Raff och Piff som stöttande kontaktytor för personer med transerfarenheter under perioden 1960 till 1970. I en bredare bemärkelse lyfts även frågan om vad dessa berättelser kan säga om villkor för personer med transerfarenheter i Sverige under 1960-talet. Via den teoretiska ingången queer temporalitet visar artikeln att kontaktannonserna samt redaktionernas svar präglas av olika former av förhandlingar och drömmar om queera liv och nya könade framtider. I en tid då det i Sverige i hög grad saknas offentliga mötesplatser för transpersoner fungerar således sextidningar som en queer horisont och passage till ett transmöjliggörande annanstans.