bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of ryuvidine as a KDM5A inhibitor
Authors: Mitsui Eishin , Yoshida Shogo , Shinoda Yui , Matsumori Yasumasa , Tsujii Hiroshi , Tsuchida Mie , Wada Shuichi , Hasegawa Makoto , Ito Akihiro , Mino Koshiki , Onuki Tetsuo , Yoshida Minoru , Sasaki Ryuzo , Mizukami Tamio
Published: July 2019

KDM5 family members (A, B, C and D) that demethylate H3K4me3 have been shown to be involved in human cancers. Here we performed screening for KDM5A inhibitors from chemical libraries using the AlphaScreen method and identified a battery of screening hits that inhibited recombinant KDM5A. These compounds were further subjected to cell-based screening using a reporter gene that responded to KDM5A inhibition and 6 compounds were obtained as candidate inhibitors. When further confirmation of their inhibition activity on cellular KDM5A was made by immunostaining H3K4me3 in KDM5A-overexpressing cells, ryuvidine clearly repressed H3K4me3 demethylation. Ryuvidine prevented generation of gefitinib-tolerant human small-cell lung cancer PC9 cells and also inhibited the growth of the drug-tolerant cells at concentrations that did not affect the growth of parental PC9 cells. Ryuvidine inhibited not only KDM5A but also recombinant KDM5B and C; KDM5B was the most sensitive to the inhibitor. These results warrant that ryuvidine may serve as a lead compound for KDM5 targeted therapeutics.
MicroRNA410 Inhibits Pulmonary Vascular Remodeling via Regulation of Nicotinamide Phosphoribosyltransferase
Authors: Gao Hui , Chen Jiwang , Chen Tianji , Wang Yifang , Song Yang , Dong Yangbasai , Zhao Shuangping , Machado Roberto F.
Published: July 2019

Nicotinamide phosphoribosyltransferase (NAMPT) upregulation in human pulmonary artery endothelial cells (hPAECs) is associated with pulmonary arterial hypertension (PAH) progression and pulmonary vascular remodeling. The underlying mechanisms regulating NAMPT expression are still not clear. In this study, we aimed to study the regulation of NAMPT expression by microRNA410 (miR410) in hPAECs and explore the role of miR410 in the pathogenesis of experimental pulmonary hypertension. We show that miR410 targets the 3′ UTR of NAMPT and that, concomitant with NAMPT upregulation, miR410 is downregulated in lungs of mice exposed to hypoxia-induced pulmonary hypertension (HPH). Our results also demonstrate that miR410 directly inhibits NAMPT expression. Overexpression of miR410 in hPAECs inhibits basal and VEGF-induced proliferation, migration and promotes apoptosis of hPAECs, while miR410 inhibition via antagomirs has the opposite effect. Finally, administration of miR410 mimics in vivo attenuated induction of NAMPT in PAECs and prevented the development of HPH in mice. Our results highlight the role of miR410 in the regulation of NAMPT expression in hPAECs and show that miR410 plays a potential role in PAH pathobiology by targeting a modulator of pulmonary vascular remodeling.
Effectiveness of simple tracing test as an objective evaluation of hand dexterity
Authors: Nishi Tomohiro , Fukudome Kiyohiro , Hata Kazutaka , Kawaida Yutaka , Yone Kazunori
Published: July 2019

This study aimed to demonstrate that the simple tracing test (STT) is useful for assessing the hand dexterity in patients with cervical spondylotic myelopathy (CSM) by comparing STT scores between healthy volunteers and CSM patients. This study included 25 CSM patients and 38 healthy volunteers. In the STT, the participants traced a sine wave displayed on a tablet device at a comfortable pace, and the tracing accuracy, changes in the total sum of pen pressures, and tracing duration were assessed. Data were analyzed using an artificial neural networks (ANN) model to obtain STT scores. All participants were evaluated using the subsection for the upper extremity function of the Japanese Orthopaedic Association (JOA) scoring system for cervical myelopathy (JOA subscore for upper extremity function) and the grip and release test (GRT). The results were compared with the STT scores. The mean STT scores were 24.4 ± 32.8 in the CSM patients and 84.9 ± 31.3 in the healthy volunteers, showing a significant difference. The STT scores showed highly positive correlations with both the JOA subscore for upper extremity function (r = 0.66; P < 0.001) and GRT values (r = 0.74; P < 0.001). Furthermore, receiver operating characteristic analysis showed an area under the curve of 0.89 (95% confidence interval, 0.76–1.00), demonstrating that STT has excellent discriminative ability. This study revealed that STT enables accurate assessment of the hand dexterity in CSM patients.
The opening of phenome-assisted selection era in the early seedling stage
Authors: Kim Song Lim , Chung Yong Suk , Silva Renato Rodrigues , Ji Hyeonso , Lee Hongseok , Choi Inchan , Kim Nyunhee , Lee Eungyeong , Baek JeongHo , Lee Gang-Seob , Kwon Taek-Ryoun , Kim Kyung-Hwan
Published: July 2019

Faster and more efficient breeding cycle is not an option to deal with unpredictable and fast global climate changes. Phenomics for collecting huge number of individuals in accurate manner could be an answer to solve this problem. We collected image data to measure plant height and manual data for shoot length to be compared. QTLs clustered of plant height and shoot length were detected in 2-week old seedlings, which was consistent with many other reports using various genetic resources in matured stage. Further, these traits are highly correlated with yield by pleiotropism or tight linkage of those traits. It implies the “phenome-assisted selection” can be applied for yield trait in rice in the very early stage to shorten the breeding cycle significantly in fast but low-cost manner.
High-throughput screening Raman microspectroscopy for assessment of drug-induced changes in diatom cells
Authors: Rüger Jan , Mondol Abdullah Saif , Schie Iwan W. , Popp Jürgen , Krafft Christoph
Published: July 2019

16 888 Raman spectra were acquired with automated localization algorithms to investigate the effect of dithiothreitol on diatoms.
Fast and sensitive simultaneous determination of antihypertensive drugs amlodipine besylate and ramipril using an electrochemical method: application to pharmaceuticals and blood serum samples
Authors: Moraes Jaqueline Tobias , Salamanca-Neto Carlos Alberto Rossi , Eisele Ana Paula Pires , Coldibeli Bruna , Ceravolo Graziela Scalianti , Sartori Elen Romão
Published: July 2019

In this work, a simple and sensitive voltammetric method using boron-doped diamond electrode for simultaneous determination of antihypertensive drugs amlodipine besylate and ramipril in pharmaceuticals and biological samples is described.
A reversibly mechanochromic conjugated polymer
Authors: Lee Jong Pil , Hwang Hyemin , Chae Songa , Kim Jong-Man
Published: July 2019

A reversibly mechanochromic conjugated polymer, based on the thermal polymerization of a diphenyldisulfide-containing bisdiacetylene, was developed.
Highly enantioselective sequential vinylogous aldol reaction/transesterification of methyl-substituted olefinic butyrolactones with isatins for the construction of chiral spirocyclic oxindole-dihydropyranones
Authors: Wang Zhen-Hua , Zhang Xia-Yan , Lei Chuan-Wen , Zhao Jian-Qiang , You Yong , Yuan Wei-Cheng
Published: July 2019

A highly stereoselective sequential vinylogous aldol reaction/transesterification of methyl-substituted olefinic butyrolactones and isatins was developed with 10 mol% Takemoto's amine–thiourea catalyst.
Cyclic dipeptide peroxosolvates: first direct evidence for hydrogen bonding between hydrogen peroxide and a peptide backbone
Authors: Churakov Andrei V. , Grishanov Dmitry A. , Medvedev Alexander G. , Mikhaylov Alexey A. , Tripol'skaya Tatiana A. , Vener Mikhail V. , Navasardyan Mger A. , Lev Ovadia , Prikhodchenko Petr V.
Published: July 2019

The crystal structures of cyclic dipeptide peroxosolvates provide valuable insight into the non-redox interaction of hydrogen peroxide with the peptide backbone.
Theoretical investigation on the reaction mechanism and kinetics of a Criegee intermediate with ethylene and acetylene
Authors: Sun Cuihong , Xu Baoen , Lv Liqiang , Zhang Shaowen
Published: July 2019

The competition among the possible pathways, the branching ratios of the adduct and the decomposition products at different temperatures and pressures have been evaluated.
The effect of milling parameters on the mechanochemical synthesis of Pd–CeO2 methane oxidation catalysts
Authors: Danielis Maila , Colussi Sara , de Leitenburg Carla , Soler Lluís , Llorca Jordi , Trovarelli Alessandro
Published: July 2019

Pd–ceria interaction can be tuned by suitable milling intensity to obtain highly active methane oxidation catalysts.
Fluorine and tin co-doping synergistically improves the photoelectrochemical water oxidation performance of TiO2 nanorod arrays by enhancing the ultraviolet light conversion efficiency
Authors: Wu Tong , Chen Changlong , Wei Yuling , Lu Ranran , Wang Leshuang , Jiang Xuchuan
Published: July 2019

Fluorine and tin co-doping changes the electronic structure of rutile TiO2 nanorod arrays, leading to much-enhanced UV light conversion efficiency and significantly improved photoelectrochemical water oxidation performance.
Field-induced slow magnetic relaxation in two-dimensional and three-dimensional Co(ii) coordination polymers
Authors: Ma Deyun , Peng Guo , Zhang Ying-Ying , Li Bo
Published: July 2019

Two two-dimensional and three-dimensional Co(ii) coordination polymers with slow magnetic relaxation are reported, which enlarge the family of high-dimensional coordination polymers exhibiting single ion magnet behavior.
Toward an operational methodology to identify industrial-scaled nanomaterial powders with the volume specific surface area criterion
Authors: Dazon Claire , Witschger Olivier , Bau Sébastien , Fierro Vanessa , Llewellyn Philip L.
Published: July 2019

A strategy for identifying nanomaterials in powder form.
Novel nitrogen doped carbon dots enhancing the anticorrosive performance of waterborne epoxy coatings
Authors: Wang Juan , Du Peng , Zhao Haichao , Pu Jibin , Yu Chengbing
Published: July 2019

Simple, versatile, and cost-effective carbon dots are reported for initiating interfacial bonding in waterborne epoxy resin anti-corrosive coatings.
Light emission driven by magnetic and electric toroidal dipole resonances in a silicon metasurface
Authors: Cui Chengcong , Yuan Shuai , Qiu Xingzhi , Zhu Liangqiu , Wang Yuxi , Li Yi , Song Jinwen , Huang Qingzhong , Zeng Cheng , Xia Jinsong
Published: July 2019

A light-emitting toroidal resonant metasurface that demonstrates simultaneous control of spontaneous emission and far-field polarization properties.
Silver nanowire inks for direct-write electronic tattoo applications
Authors: Williams Nicholas X. , Noyce Steven , Cardenas Jorge A. , Catenacci Matthew , Wiley Benjamin J. , Franklin Aaron D.
Published: July 2019

A water-based silver nanowire ink for the room temperature printing of highly conductive traces onto biological and nonplanar surfaces.
Hybrid light emitting diodes based on stable, high brightness all-inorganic CsPbI3 perovskite nanocrystals and InGaN
Authors: Zhang Chengxi , Turyanska Lyudmila , Cao Haicheng , Zhao Lixia , Fay Michael W. , Temperton Robert , O'Shea James , Thomas Neil R. , Wang Kaiyou , Luan Weiling , Patanè Amalia
Published: July 2019

Hybrid light emitting diodes (LEDs) operating at multiple wavelengths are realized by combining stable, high brightness all-inorganic CsPbI3 and InGaN LEDs.
Facile and low-cost synthesis of pure hematite (α-Fe2O3) nanoparticles from naturally occurring laterites and their superior adsorption capability towards acid-dyes
Authors: Dissanayake D. M. S. N. , Mantilaka M. M. M. G. P. G. , Palihawadana T. C. , Chandrakumara G. T. D. , De Silva R. T. , Pitawala H. M. T. G. A. , Nalin de Silva K. M. , Amaratunga G. A. J.
Published: July 2019

High purity hematite nanoparticles have been synthesized by a facile method using naturally occurring laterites for industrial dye effluent treatment applications.
Bayesian semi-supervised learning for uncertainty-calibrated prediction of molecular properties and active learning
Authors: Zhang Yao , Lee Alpha A.
Published: July 2019

We report a statistically principled method to quantify the uncertainty of machine learning models for molecular properties prediction. We show that this uncertainty estimate can be used to judiciously design experiments.
A deep neural network model for packing density predictions and its application in the study of 1.5 million organic molecules
Authors: Afzal Mohammad Atif Faiz , Sonpal Aditya , Haghighatlari Mojtaba , Schultz Andrew J. , Hachmann Johannes
Published: July 2019

Computational pipeline for the accelerated discovery of organic materials with high refractive index via high-throughput screening and machine learning.
A highly efficient 2D siloxene coated Ni foam catalyst for methane dry reforming and an effective approach to recycle the spent catalyst for energy storage applications
Authors: Krishnamoorthy Karthikeyan , M. S. P. Sudhakaran , Pazhamalai Parthiban , Mariappan Vimal Kumar , Mok Young Sun , Kim Sang-Jae
Published: July 2019

An effective approach to reuse the carbon deposited spent catalyst (siloxene/Ni foam) after the methane dry reforming process is demonstrated by utilizing them as electrodes for supercapacitor devices.
Pure and Zr-doped YMnO3+δas a YSZ-compatible SOFC cathode: a combined computational and experimental approach
Authors: Moreno Botello Zulma L. , Montenegro Alejandra , Grimaldos Osorio Nicolas , Huvé Marielle , Pirovano Caroline , Småbråten Didrik R. , Selbach Sverre M. , Caneiro Alberto , Roussel Pascal , Gauthier Gilles H.
Published: July 2019

Zr doping stabilizes the interstitial oxygen in layered manganite YMnO3and provides O2−migration path with a lower energy barrier. The resulting material is of high interest as a YSZ compatible SOFC cathode.
The effect of structural dimensionality on carrier mobility in lead-halide perovskites
Authors: Hartono Noor Titan Putri , Sun Shijing , Gélvez-Rueda María C. , Pierone Polly J. , Erodici Matthew P. , Yoo Jason , Wei Fengxia , Bawendi Moungi , Grozema Ferdinand C. , Sher Meng-ju , Buonassisi Tonio , Correa-Baena Juan-Pablo
Published: July 2019

Changes in perovskite structural dimensionality brought by mixing A-site cations play an important role in determining the measured charge carrier mobility, and in the solar cell performance.
Depletion layer controls photocatalytic hydrogen evolution with p-type gallium phosphide particles
Authors: Zhao Zeqiong , Willard Emma J. , Dominguez Julius R. , Wu Zongkai , Osterloh Frank E.
Published: July 2019

p-Type gallium phosphide (p-GaP) is an established photocathode material for hydrogen evolution, however, photocatalytic hydrogen evolution from p-GaP photocatalysts generally proceeds with very low activity. This can be understood on the basis of the space charge layer model presented here.
Pore-structure-directed CO2 electroreduction to formate on SnO2/C catalysts
Authors: He Yeheng , Jiang Wen-Jie , Zhang Yun , Huang Lin-Bo , Hu Jin-Song
Published: July 2019

Three-dimensional porous carbon sheets with abundant micropores and macropores are used to uniformly disperse SnO2 nanoparticles with high loading, and the obtained SnO2/PC exhibits efficient formate production from electrochemical CO2 reduction.
LncRNA AWPPH overexpression predicts the recurrence of periodontitis
Authors: Wang Xiaofang , Ma Feng , Jia Peizeng
Published: July 2019

Long non-coding RNA (LncRNA) AWPPH is a recently identified oncogenic lncRNA, while its role in other human diseases is still unknown. Blood samples from 80 periodontitis (periodontitis group) patients and 66 healthy controls (control group) who were admitted and treated by Peking University School and Hospital of Stomatology, expression levels of lncRNA AWPPH were detected by RT-PCR. In the present study, we showed that, before treatment, lncRNA AWPPH in plasma was up-regulated in periodontitis patients than in healthy controls. After treatment, expression levels of lncRNA AWPPH reduced significantly. Patients were followed up for 2 years to recorded recurrence. Compared with plasma levels of lncRNA AWPPH on the day of discharge, lncRNA AWPPH expression level increased significantly in patients with recurrence but not in patients without recurrence during follow-up. Based on Youden’s index, patients were divided into high and low lncRNA AWPPH groups according to its expression level on the day of discharge. It was observed that the recurrence rate of periodontitis is significantly higher in high lncRNA AWPPH group than in low lncRNA AWPPH group. LncRNA AWPPH overexpression predicts the recurrence of periodontitis.
Integrated fault estimation and fault tolerant attitude control for rigid spacecraft with multiple actuator faults and saturation
Authors: Zhang Xiaobo , Zhou Zepeng
Published: July 2019

This study proposes an integrated fault estimation (FE) and fault‐tolerant control design for a rigid spacecraft attitude system with inertia uncertainties, external disturbances, input saturation, and different type multiple actuator faults. A barrier function is first introduced to eliminate the effects of inertia uncertainties and disturbances in the design of the sliding mode FE observer. By using the non‐singular fast terminal sliding mode control technology, a finite‐time fault‐tolerant attitude stabilisation controller and a finite‐time fault‐tolerant attitude tracking controller are designed to guarantee that the closed‐loop attitude system has a good fault‐tolerant performance under actuator faults. Furthermore, when considering actuator saturation, an auxiliary system is utilised to compensate for the saturation. The stability of the closed‐loop system is analysed by Lyapunov theory. Finally, the effectiveness of the proposed control approach is demonstrated via simulation results.
Concurrent cardiopulmonary detection using 12/24 GHz harmonic multiport interferometer radar architecture
Authors: Chioukh Lydia , Djerafi Tarek , Deslandes Dominic , Wu Ke
Published: July 2019

A harmonically driven bio‐radar based on the technique of a multiport interferometer (six‐port) technique is proposed and studied in order to improve the performance of vital signs monitoring. The feasibility of estimating cardiopulmonary parametric signatures by deploying a harmonic multiport interferometer radar is presented. This scheme is helpful to reduce the noise floor and the effects of undesirable parasitic harmonics of breathing and intermodulation. A theoretical analysis is developed to explain why a better heart‐beat detection using the proposed harmonic six‐port radar architecture can be achieved. The well‐known null point problem usually encountered in such radar detections of heart‐beating signs is alleviated by the insertion of a fixed 45° phase shift between the two different frequencies in the six‐port discriminator without an actual phase‐shifter. Simulations are carried out to investigate detection accuracy and sensitivity issues for monitoring the vital signs by cancelling the breathing harmonics and intermodulation products. The concept is then validated by the measured results of an experimental prototype using the proposed harmonic six‐port radar platform operating at 12 GHz (fundamental) and 24 GHz (harmonic).
Empirical characterisation of the indoor multi‐user MIMO channel in the 3.5 GHz band
Authors: Torres Rafael P. , Pérez Jesús R. , Basterrechea José , Domingo Marta , Valle Luis , González Jorge , Rubio Lorenzo , Rodrigo Vicent M. , Reig Juan
Published: July 2019

This study presents an analysis of the capabilities of using multi‐user multiple input multiple output (MU‐MIMO) in indoor environments at the 3–4 GHz band through an empirical characterisation of the MU‐MIMO channel, obtaining a statistical description of the degree to which this specific multi‐user channel verifies the condition of ‘favourable propagation’. Different metrics have been considered to measure the degree of orthogonality between the channels, such as the orthogonality coefficient or the condition number. In addition, in order to obtain a direct measure of the goodness of the channel in terms of the achievable spectral efficiency, the capacity of the channel has been calculated for different numbers of users and base station antennas and compared with theoretical i.i.d. Rayleigh channels.
Dynamic range enhancement of OTDR using lifting wavelet transform‐modified particle swarm optimisation scheme
Authors: Tangudu Ramji , Sahu Prasant Kumar
Published: July 2019

The optical time domain reflectometry (OTDR) is the only investigation tool for the optical fibre continuity measurement and is capable of verifying inline splices and locating fibre faults. As per the literature review, most of the distributed fibre sensors are designed using OTDR principle. Dynamic range plays a major role in such instruments. Dynamic range enhancement of OTDR is proposed using the lifting wavelet transform (LWT)‐modified particle swarm optimisation (MPSO) scheme. This scheme enables us to design customised lifting wavelet filters to improve the signal‐to‐noise ratio which in turn improvises the dynamic range. This study proposes and demonstrates the application of LWT along with the MPSO evolutionary algorithm to obtain optimum threshold, in order to mitigate the noisy lifting wavelet coefficients effectively. The proposed scheme is employed for OTDR measurement up to 50 km (silica optical fibre), using 10 dBm of laser input power. As compared with the conventional wavelet regularised deconvolution schemes, the authors’ proposed scheme offers a 3.42 dB enhancement in the dynamic range under a lower computational complexity requirement. The proposed study is carried out using computer simulation using MATLAB 15.0 software. The results were experimentally validated.
Image denoising based on wavelet thresholding and Wiener filtering in the wavelet domain
Authors: Fan Wen‐quan , Xiao Wen‐shu , Xiao Wen‐shu
Published: July 2019

Wavelet transform has become a very important tool in the field of image denoising. A wavelet transform is a localised analysis of time (space) frequency. It uses a telescopic translation operation to gradually multi‐scale refine the signal function and finally adapt to time frequency. One popular approach involves thresholding the wavelet coefficients by using the soft or hard threshold. Another method of image denoising is the Wiener filtering in the wavelet domain. In this study, Gaussian white noise has been added to two grey scale images and the two different denoising methods have been used. By comparing the performance of the two methods, it can be found that the Wiener filtering in the wavelet domain is more prowerful.
Multipath effect analysis and pre‐distortion processing for jamming on wideband ground radar through antenna sidelobe
Authors: Shi Rong , Xu Jiantao
Published: July 2019

The multipath transmission has a serious effect on jamming efficiency in a short distance ECM task for wideband ground radars. After the sidelobe gain model for a large antenna is introduced, the characteristics of multipath channel in time and frequency domain are analysed. The statistical characteristics about the amplitude change of the intercepted pulse signals and the occurrence conditions of frequency selective fading are explained. The short time compatibility between reconnaissance channel and jamming channel is used to pre‐distort the jamming signal, and the serious influence of multipath transmission on the jamming signal is greatly eliminated. The fidelity of deception jamming on the radar is greatly improved. The validity of theoretical analysis is verified by simulation experiments. It provides an important theoretical guidance for a short distance electronic counter measures (ECM) task against ground radars.
Multi-wavelength campaign on NGC 7469
Authors: Grafton-Waters S. , Branduardi-Raymont G. , Mehdipour M. , Page M. J. , Behar E. , Kaastra J. , Arav N. , Bianchi S. , Costantini E. , Ebrero J. , Di Gesu L. , Kaspi S. , Kriss G. A. , De Marco B. , Mao J. , Middei R. , Peretz U. , Petrucci P.-O. , Ponti G.
Published: July 2019

Aims.We aim to investigate and characterise the photoionised X-ray emission line regions within the Seyfert 1 galaxy NGC 7469.

Methods.We applied the photoionisation model,PION, within the spectral fitting codeSPEXto analyse the 640 ks reflection grating spectrometer spectrum of NGC 7469 gathered during anXMM-Newtonobserving campaign in 2015.

Results.We find the emission line region in NGC 7469 to be multiphased, consisting of two narrow components with ionisation parameters of logξ = 0.4 and 1.6. A third, broad emission component, with a broadening velocity ofvb ∼ 1400 km s−1and an outflow velocity ofvout ∼ −4500 km s−1is required to fit the residuals in the O VIItriplet at around 22 Å. Assuming a volume filling factor of 0.1, the lower distance limits of the narrow emission line region components are estimated for the first time at 2.6 and 2.5 pc from the central black hole, whereas the broad component has an estimated lower bound distance between 0.004 and 0.03 pc, depending on the assumed plasma parameters. The collisionally ionised plasma from the star burst region in NGC 7469 has a plasma temperature of 0.32 keV and an outflow velocity of −280 km s−1, which is consistent with previous results in this campaign. In addition, we model the photoionised plasma of the warm absorber (WA) in NGC 7469 and find that it consists of three photoionised phases with different values ofξ,NHandvout. The upper bound distances of these WA components are 1.9, 0.3, and 0.6 pc, respectively, consistent with archival results.

Conclusion.The environment of NGC 7469 is a complex mix of plasma winds absorbing and emitting X-rays. We find the picture painted by our results can be attributed to line emitting plasma located at distances ranging from near the black hole to the torus and beyond the ionised outflows.
Acoustic oscillations and dynamo action in the G8 sub-giant EK Eridani,
Authors: Bonanno A. , Corsaro E. , Del Sordo F. , Pallé P. L. , Stello D. , Hon M.
Published: July 2019

We present further evidence of acoustic oscillations in the slowly rotating overactive G8 sub-giant EK Eri. This star was observed with the 1m Hertzsprung SONG telescope at the Observatorio del Teide for two different runs of 8 and 13 nights, respectively, that were separated by about a year. We determined a significant excess of power aroundνmax = 253 ± 3 μHz in the first observing run and were able to determine a large separation, Δν = 16.43 ± 0.22 μHz. No significant excess of power was instead detected in a subsequent SONG observing season, as also supported by our analysis of the simultaneous TESS photometric observations. We propose a new amplitude-luminosity relation in order to account for the missing power in the power spectrum. Based on the evolutionary stage of this object, we argue that a standardα2Ω dynamo cannot be excluded as the possible origin for the observed magnetic field.
Substantiating a technique to process hard rock involving extraction of valuable components and use of wastes to form mesorelief
Authors: Babii Kateryna , Ikol Oleksandr , Malieiev Yevhenii
Published: July 2019

A technique to process rock mass from hard-rock technogenic media has been developed; it is aimed at recovery of mineral losses, restoration of the environment at the territory of mining enterprises by means of rock mass extraction, its processing and redistribution for the purposes of land recultivation and landscape restoration. Classification of dry ore-containing hard rocks of dumps has been developed; that has made it possible to improve technological scheme of the processing of rock mass from technogenic media, emphasize its variants of use, and specify the required facilities and their productivity. Scientific value of the paper is in determining the effect of changes in the losses in pre-processing dry wastes upon the yield of industrial product and wastes; the effect has demonstrated that the yield of industrial product is in polynomial dependence upon the pre-processing losses while yield of tailings is in the power dependence. Practical implications of the paper are in the fact that the proposed method helps form mesorelief with the properties close to the natural one. The method involves restoration of the initial landscape with the help of opening hard rocks followed, completed by laying water-bearing and potentially fertile layers.
Reduction of technogenic load from sludge collectors due to separation and dehydration of the stored material
Authors: Bubnova Olena , Shevchenko Oleksandr
Published: July 2019

Purpose: the identification of geomechanical problems of mining industry wastes accumulation and substantiation of the ways for their solution with the possibility of processing the watery technogenic feedstock. It has been shown that in order to reduce the technogenic load, it is necessary to reduce the area of land under the waste ponds and the accumulated volumes themselves of mining and enrichment wastes. It has been revealed that the mineral stock, formed from wide grain-size classes with a high content of particles less than 0.2 mm, is dewatered up to 18 – 22 % by traditional methods and is practically not classified. A mathematical model has been proposed of screening and dewatering kinetics, which takes into account comprehensively the initial distribution of particles and liquid throughout the height of the screened material layer, segregation, mixing, sifting, vibrational transportation features and change in the height of the layer. The use of technology will allow: increase the economic efficiency of enterprises; to expand the feedstock base for construction, coke and chemical industries and power industry; to solve the problems of creating additional containers for storing the wastes; to improve significantly the environmental situation in the mining and processing regions.
Increase of energy efficiency of mine fans work on a mine vent network
Authors: Bunko Tetiana , Shyshov Maksym , Bokii Oleksandr , Belikov Anatolii , Zhalilov Oleksandr , Kokoulin Ivan
Published: July 2019

The increase of energy efficiency of main fans (MF) work is the basic condition of perfecting the mine ventilation system. During realization of multi-fan ventilation there is the non-productive «overbalancing» of vent flow from a weaker towards more powerful ventilator which causes decline of work efficiency of both. The questions of reducing the MF mutual influence on the outgoing air flow and increasing the aerodynamic quality of vent network have been studied and considered insufficiently. It is proposed to use the method of calculating the effective MF operating conditions taking into account the mutual influence of MF and areas-users of fresh air in mine ventilation network and on the basis of criterion of estimating the MF mutual influence, which will allow to enhance the energy efficiency of mine ventilation and labour safety of subsurface miners.
The solid ingredient properties influence on the energy characteristic of the coal-water slurry fuel flow
Authors: Chernetska–Biletska Nataliia , Shvornikova Hanna , Podoliak Kostiantyn , Kyrychko Serhii , Miroshnykova Mariia
Published: July 2019

The article analyses the process of making the coal-water slurry fuel. The main factors influencing the slurry rheological characteristics and, therefore, energy costs during its transportation are determined. The main attention is paid to the original coal ash content efficiency influence on the energy characteristics of the coal-water slurry fuel. In the work, the transformations of classical rheological equations were carried out taking into account the experimental dependence of the coal-water fuel effective viscosity on the feedstock ash content. As a result of the conducted transformations the dependence to determine the specific pressure loss due to the feedstock ash content was obtained. This has enabled to supplement the eligibility determination techniques for the grade of the coal used as the feedstock for the preparation of the coal-water fuel with rational energy and rheological characteristics. To substantiate the theoretical calculations, the article presents the results of the experimental studies on the effect of coal ash content on the specific pressure losses.
The issue of loading the material in a vibro-impact grinder
Authors: Fedoskina Olena , Fedoskin Valerii , Loginova Anastasiia
Published: July 2019

The article discusses the basic principles of force loading of a material in a vibro-impact grinder with a vertical and inclined working chamber. It is shown that in a grinder with a vertical working chamber the control of the material loading is limited by the presence of a relationship between the vertical and rotational oscillations of the jaws. Vibro-impact grinder with an inclined working chamber represents a new class of machines. A mathematical model of the process of interaction of the jaw with a piece of material when moving it in the working chamber is presented. Equations and graphical dependencies are obtained, which determine the phase angle of the moment of clamping the piece in the working chamber. The modes of power loading of the material in the working chamber were analyzed.
Pigments based on blast furnace slag from waste water
Authors: Frolova Liliya , Butyrina Tetyana , Galivets Yurii
Published: July 2019

In this work we prove the possibility of blast furnace slag use as a basis for green, black, brown and orange pigments. We presented kinetic characteristics of the process, as well as the main characteristics of the products obtained. We found that a high degree of conversion is provided by both chemical reaction and adsorption. Through microscopic analysis we identified pigment dispersion. We worked out technological scheme of the process.
Distribution of seisms foci during the mining of 19th eastern longwall and Eastern inclined longwall #3
Authors: Karhapolov Andrii , Prykhodchenko Svitlana , Chelkan Vera
Published: July 2019

The paper presents the results performed at the O.F. Zasiadko mine seismological observations on the registration and location of seisms that occur during the mining of the m3 bed. According to the constructed magnitude-frequency relationship for the worked out longwalls, it was concluded that the longwalls worked out in different mining-geological conditions differ in the relative energy of seisms, in their number, recording time and spatial location of foci.
Experimental and analytical studies to substantiate the blasting operations rational parameters in the hard media destruction
Authors: Kratkovskyi Ihor , Ishchenko Oleksii
Published: July 2019

The method of sieve analysis studied particle size distribution of the products explosive destruction of sand-cement models with elliptical compensatory cavity in its middle that were destroyed with use of various designs explosive charges and built the cumulative distribution curves. It was established that the area of the newly formed surface of these models destruction products, destroyed by an explosion of variable cross section charges, increased 1.45 times as compared with charges of other structures (boiler in the extension of the charge end, solid structure). The middle diameter of particles increased at 50-60 %. According to the results of the fractional composition, distribution of the products models destruction for different designs and geometric parameters of the compensation cavity has been defined by the regression lines. According to the cumulative distribution curves of the products of destruction of a model with different geometrical parameters of the compensation cavity, around which various designs of explosive charges were exploded, the equations of the regression lines was determined. Based on the obtained dependences of the regression-correlation analysis, mathematical models have been developed to optimize the choice of rational parameters of compensation cavities and explosive charge structures. Recommendations for their use in mines are given.
Water stability influence of host rocks on the process of water filtration into mine working with frame and roof-bolting support
Authors: Krukovska Viktoriia , Vynohradov Yurii
Published: July 2019

The water stability influence of host rocks on water filtration process from the undermined aquifer to the mine working, depending on the way of its fastening has been studied in the paper. When solving the problem of water filtration in a deformable massif, the finite element method was used. The results of calculations are presented of the filtration permeability of the coal-bearing massif, the water pressure and the value of the water inflow into mine working in the cases of mining operations in sandstone and argillite. It is shown that the use of roof-bolting support prevents the development of the fractures formation process in the mine working roof, preserving the rocks in a natural, monolithic state. As a result, the process of water filtration from water bearing rock layers is constrained, which prevents or significantly reduces the soaking of border roof rocks. The use of roof-bolting fastening several times reduces the water inflow into mine working, located even in water-permeable rocks. The application of the roof-bolting support as a technological method for reducing the water inflow into mine workings has been substantiated.
Modification of the roof bolt support technology in the conditions of increasing coal mining intensity
Authors: Krukovskyi Oleksandr , Bulich Yurii , Zemlianaia Yuliia
Published: July 2019

The modification of the technology roof bolt supporting of mine workings in the conditions of increasing the coal mining intensity has been made. The technological schemes have been developed for the phased construction of roof bolting and frame support. This schemes make it possible to temporarily postpone the setting of frames in the mine working face, reduce the time and labour intensity for covering with a grid of the mine working arch and setting the bolts, as well as to increase the safety. The analysis of changes in the stress state of the border massif during the phased construction of roof bolting and frame support has been made. It is shown that the technology of phased construction of roof bolting and frame support ensures the maintaining a stable state of host rocks. In addition, the time between the extraction of the coal-rock mass and the setting of the primary support, as well as the distance between the face and the first row of roof bolts has been reduced to a minimum. The suggested approach makes possible to ensure the rate of preparatory mine workings development that are necessary for the intensification coal mining.
Numerical simulation of the stress state of the layered gas-bearing rocks in the bottom of mine working
Authors: Krukovskyi Oleksandr , Krukovska Viktoriia
Published: July 2019

The mathematical model has been developed for the coupled processes of the rock massif deformation and gas filtration in a disturbed area around mine working, in the bottom of which there are hard and soft gas-bearing rocks. When solving the problem, the finite element method was used. The calculation results of the displacements, stresses and pressures of methane in the studied area are represented in the paper. It is shown that the difference in the physical and mechanical properties of the bottom rocks of mine working causes the non-uniform distribution of geomechanics and filtration parameters. In more strong sandstone, the stresses concentration increases. Therewith, an intensive process of fractures formation takes place in the argillite and the coal. Methane from the upper part of the gas-bearing sandstone is filtered into the mine working, the destruction of the coal interlayer is accompanied by release of methane and its accumulation under the layer of a strong sandstone. The development of a zone of inelastic deformations leads to the destruction of sandstone. In case of brittle destruction, with the formation of fractures of a certain length, a breakthrough of methane may occur out of the bottom into mine working.
Numerical analysis of changing the force factors in temporary lining at the tunnel construction by the NATM
Authors: Kuprii Volodymyr , Petrenko Volodymyr , Kuprik Sofiia , Kripak Yevhenii
Published: July 2019

The paper presents the results of a numerical analysis of force factors in temporary lining at the tunnel construction by New Austrian Tunneling Method (NATM). The relevance of the performed research is substantiated by the complexity of the temporary lining operation in the form of arches combination, anchors, and shotcrete that arose during construction of the Beskydskyi tunnel in Ukraine. NATM, used in construction, is associated with a change in the sectional area of the working and a staged installation of temporary lining, which leads to a gradual change in the stress-strain state of the “temporary lining – surrounding massif” system. In turn, this leads to a change in the force factors (bending moments and normal forces) in temporary lining. In this study, a series of finite-element models simulating the stages of rock excavation and installation of lining elements have been developed and analyzed. The obtained results allowed to determine the cardinal change of force factors in temporary lining, depending on the stage of construction. Changing the force factors at different stages of the tunnel construction by the NATM makes it possible to perform an optimal selection for temporary lining location.
Forecast of the position of promising sand reservoirs in the cross-section of the carboniferous gas-bearing stratum
Authors: Lukinov Viacheslav , Zhykaliak Mykola
Published: July 2019

The results of the study of the influence of overburden stress in a solid mass undisturbed by mine workings on the compaction of sandstones within mine fields, exploration areas of Donbas coal deposits and some gas condensate and oil and gas condensate deposits of the Dnipro-Donets Depression (DDD) are presented. Regularities of changes in gas-bearing properties of porous reservoirs with the increase of overburden stress in an undisturbed solid mass, or its decrease in mine conditions are considered. The possibilities of rapid assessment of the forecast position of prospective sand reservoirs in the cross-section of the gas-bearing stratum are shown. Methods are proposed for calculating the position of sandstones of gas-bearing stratum, in which it is advisable to search for gas accumulations and its extraction in the coal and gas, oil and gas condensate and gas condensate fields of Donbas and DDD.
Method of calculating the parameters of the mountain pressure epure
Authors: Malich Mykola , Katan Volodymyr , Vasyliev Dmytro , Chuhunkov Ihor
Published: July 2019

Elevated bearing load pressure is formed near the exposed part of the coal seam, compared with static stresses normal to the reservoir. The loading of the near-bottom part of the coal seam is formed by linearly damped, according to the principle of Saint-Venant, from the bottom of the face to the massif of the tangential stresses from contact friction between the formation and lateral enclosing rocks in the form of a reference rock pressure, the epure of which is described by a convex quadratic function whose initial value is normal stress at the top of the bottom hole fracture, and the final stress is to the rock pressure in the zone of the intact massif. In connection with the above scientific position, a method has been developed for determining the vertical normal stress at the top of the bottom hole fracture, the length of the epure, and the distance from the bottom to the maximum of the reference pressure.
Control of degassing systems
Authors: Novikov Leonid
Published: July 2019

The methods and means of control for gas pipelines, as well as signs of liquid accumulation are present. Dependencies for determining the volume flow of gas mixture and the absolute equivalent roughness for internal surface of degassing pipeline is given. The graph of changes in local pressure losses of the gas mixture in the place of fluid accumulation is given. Analysis of the results of experimental studies of the aerodynamic drag of pipeline section in the place of liquid accumulation is out. Results of measurements for methane concentration in ventilation working out when stopping degassing are present.
Gas engines secondary heat recovery to electrical energy
Authors: Oksen Yurii , Trofymova Olena , Bobryshov Oleksandr , Lukisha Anatolii , Pryvalov Volodymyr
Published: July 2019

The schema for gas engine waste heat recovery to electrical power by dual circuit power generation unit with different working agents has been developed. The method and the most efficient power generation unit heat mode calculation algorithm under the conditions of the given restrictions on the temperature differences in the heat exchangers has been developed. Based on the mathematical modeling of heat modes it has been stated that 4200 kW of heat power can be utilized to generate 520 kW of electrical power for JMS 620 gas engine. It has been calculated that the efficiency of secondary heat recovery to electrical power reaches 12.3 % which leads general efficiency increase for a gas engine from 42.9 up to 50.0 %.
Using the method of integral Fourier transform to solve the problem of nonstationary deformation of an elastic medium
Authors: Sapehin Volodymyr
Published: July 2019

For the first time, for solving the wave equation, the method of the integral Fourier transform for an elastic medium under the action of variable internal pressure was used. This equation contains singularities of the second kind, which were excluded from the calculation by the half division method. The main parameters of the process of non-stationary deformation affecting the magnitude of stresses and displacements for the case of plane deformation are established.
Conceptual basis of mining intensification by the geomechanical factor
Authors: Skipochka Serhii
Published: July 2019

The goal of the work was to develop a concept of intensification of mining operations, taking into account geomechanical processes occurring in the “rock massif – mining workings – support and protective structures” system. The article is the result of theoretical and experimental research materials analysis and synthesis, carried out for the conditions of coal, non-metallic and iron-ore mines. Positive and negative geomechanical processes and phenomena, occurring during intensification of mining operations, have been substantiated. A set of technical and technological solutions to eliminate the negative phenomena associated with high mining rates development of mineral resources has been proposed. Recommendations, presented in this article, will significantly reduce the conditionally fixed costs of mining production and improve miner’s safety.
Substantiation of fuzzy logic algorithms for control problems of a geotechnical systems
Authors: Slashchov Anton , Yalanskyi Oleksii
Published: July 2019

The article presents results of study of intelligent fuzzy logic algorithms developed on the basis of fuzzy logic methods for information system of the mine safety system. In order to prevent emergency situations caused by the lost geotechnical system stability due to the uncertain behavior of the rock mass, a new fuzzy controller was designed which could generate an additional control signal. For the fuzzy controller, methods of data fuzziness, inference and de-fuzziness were validate, and linguistic rules were designed in order to control parameters of the geotechnical system. With the help of the Cauchy problem solved by Runge-Kutta method of the 4th order, designed a software model of the proposed system which simulated the system operation. The model has proved operability and static stability of the developed algorithms. Output signal of the fuzzy controller can be used as information for estimating risk for geotechnical systems, preventing possible emergency situations and, consequently, can improve job safety in the mines.