bluuebunny/crossref_metadata_2025 huggingface dataset:
Adoption of Briquettes of Organic Matter as an Environmentally Friendly Energy Source in Uganda
Authors: Mahoro Brenda G. ,   Kampala International University, Eniru Innocent E. , Omuna Daniel , Akiyode Oluwole , Musinguzi Danson ,   Kampala International University,   Kampala International University,   Kampala International University,   Kampala International University
Published: May 2023

Demand for inexpensive alternative fuels and briquettes to bridge the gap between cooking, water heating, and heating production processes has been expanding by the day, due to the current fuel crisis and the ever-increasing costs of electricity and wood charcoal in Kampala and its environs. The goal of this study was to determine the different types of biomass briquettes and associated technology that are available in Kampala. Face-to-face interviews and questionnaires were used to collect data on the numerous varieties of biomass briquettes that are commonly used by Kampala families, as well as the raw materials used by briquette producers. Descriptive statistics techniques were employed. According to the statistics, the most often utilized briquettes in Kampala are stick briquettes, honeycomb briquettes, cylindrical, round, and doughnut-shaped briquettes. While the majority of households continue to use expensive and unreliable energy sources such as wood charcoal, gas, and electricity, using briquettes is less expensive and has the potential to reduce deforestation, minimize waste streams, and reduce indoor air pollution, reduce odors, and increase local job creation. Households that use briquettes lamented a lack of available technology, a lack of equipment for making their own, and a shortage of well-trained or skilled people to assist in waste sorting to gather organic matter for briquette production. It was concluded that carbonized round briquettes are preferred because non-carbonized briquettes are extremely scarce and that a number of factors significantly deterred individuals from investing in biomass briquette technology, including government laxity in providing incentives and a failure to create favorable conditions for individuals to invest in biomass briquette energy production and utilization.
Analysis of Temperature-Dependent Womersley Flow of a Power-Law Fluid through a Porous Medium on Analytic Functions
Authors: A PETER, B ,   Kampala International University, E PETER, R , A IDOWU, S ,   Kampala International University,   Kampala International University
Published: May 2023

The goal of this research is to look into the analytic functions for temperature-dependent womersley flow of a power-law fluid through a porous material. Bessel functions are a set of solutions to a second-order differential equation that can appear in a variety of contexts. Mechanics, electrodynamics, elasticity, hydrodynamics, electrical engineering, oscillatory systems, electro engineering, and maritime engineering, heat distribution over an area (smartphones), pressure vessel design, microphone design, solid state physics, and celestial mechanics are some of the applications of Bessel functions. The following tools were used: analytical functions theorems, Microsoft Excel, and Maple Software 2018. The physical properties that describe a power-law fluid passing through a porous media have a significant impact on the flow system's mass transfer. The temperature-dependent parameter should be maintained well enough for optimal production, according to field and production engineers.
Heydar Aliyev is the architect of science and education reforms in Azerbaijan
Authors: Nailə Rauf qızı Əliyeva
Published: May 2023

Nowadays, the level of development of countries is measured not only by economic criteria, but also by the situation in its educational system and the existing personnel potential. This is not accidental. Because all negative and positive processes in each country are closely related to the human factor. A reliable way of comprehensive and sustainable development is to pay more attention and care to science and education and organize it according to modern world standards. That is why the West and other advanced countries of the world attach primary importance to this area in order to maintain their development levels and move towards new goals. The creation of a turn in the management system laid the foundation for the development of education, science, and the application of democratic principles to practical work. Carrying out reforms in the higher education system, introducing innovations in training practices had a positive effect on the high level of educational and scientific work in higher schools, and on the efficient use of the power of scientific potential. The Nationwide leader Heydar Aliyev always said about creating a globalized society which can be achieved only through science, education and new thinking.
Model of entrepreneurship of Heydar Aliyev and its development in the modern period
Authors: Taleh Balağa oğlu Əkbərov
Published: May 2023

In the article, the necessity of modeling research approaches to entrepreneurship is substantiated and the signs of creating a business environment corresponding to it are defined. In model of entrepreneurship of Heydar Aliyev, the author also examined the system of legal regulation of state support measures for entrepreneurship; its unique characteristics and the outcomes of its successful application in contemporary times were defined.
Period of Heydar Aliyev in the multiculturalism policy in Azerbaijan
Authors: İlqar Həsrət oğlu Hüseynov
Published: May 2023

Multiculturalism is primarily related to the interaction and enrichment of national cultures, recognition of moral values and norms. When Heydar Aliyev was in power, he had a tolerant attitude to all people, regardless of their religion, language, or race, and this attitude became one of the fundamental elements of our state and the philosophy of Azerbaijanism. The flourishing of multiculturalism in our country is directly related to the name of Great Leader Heydar Aliyev. The Great Leader Heydar Aliyev believed that race, religion, nationality, and material wealth could never lead to the superiority of one person over another. The National leader paid special attention to the development of Azerbaijani culture, as a result of this development, the model of “Azerbaijani multiculturalism” was formed in the modern stage of our civilization. The “Azerbaijani multiculturalism” model is already actively used in foreign countries. This model includes various ethno-cultural traditions such as, household, religion, ethics, aesthetics, etc. It is characterized by uniting national value system. At present, the “Azerbaijani multiculturalism” model has become an effective tool for maintaining stability and peace in the region and eliminating conflicts related to it on a global scale. The Great Leader rendered invaluable services in the formation and development of the “Azerbaijani multiculturalism” model. Heydar Aliyev maintained his loyalty to his nation and religion while working in high positions during the years of Soviet rule, and attached great importance to multicultural values.
Heydar Aliyev's state language policy
Authors: Şaiqə Həmzə qızı İskəndərova
Published: May 2023

The National Leader Heydar Aliyev who played an exceptional role in the fate of Azerbaijani people during the soviet period and after getting independence, had the greatest services for the development of the Azerbaijani language. He put his signature under a myriad of legal acts in order to protect, develop, purify and promote our language. Heydar Aliyev was engraved on the memory of this nation due to his invaluable services to the Azerbaijani people, as well as the Azerbaijani language.
A ARTE E A CIÊNCIA DA INTEGRAÇÃO DA ENERGIA FOTOVOLTAICA NO AMBIENTE CONSTRUÍDO – PARTE 2: ESTUDO DE CASO
Authors: Pauli Custódio Isadora , Portolan dos Santos Ísis , Rüther Ricardo
Published: May 2023

Para explorar o máximo potencial de qualidade de integração fotovoltaica no ambiente construído, características técnicas e não-técnicas devem ser consideradas. Em relação às questões não-técnicas, é necessário que arquitetos e engenheiros saibam como a utilização de módulos fotovoltaicos em edificações pode ser interpretada a partir de teorias de percepção arquitetônica. A tradição da crítica da arquitetura fotovoltaica é objetiva e explora as características visuais das construções. Entretanto, a essência da arquitetura é o vazio do espaço o qual pessoas experimentam. Este estudo é dividido em dois artigos: Parte 1: investigação teórica e Parte 2: estudo de caso. A Parte 1 definiu as interpretações tradicionais da arquitetura fotovoltaica e propôs um método para identificar como a percepção dos sistemas fotovoltaicos influencia a experiência espacial arquitetônica. Esta é a Parte 2 do trabalho, a qual demonstra a aplicação do método a um estudo de caso, as edificações do Centro de Pesquisa e Capacitação em Energia Solar da Universidade Federal de Santa Catarina (Laboratório Fotovoltaica/UFSC). Os resultados pretendem servir de inspiração, contribuindo para a ampliação do uso de módulos fotovoltaicos como forma de expressão arquitetônica e para a redução da lacuna que existe entre cientistas e arquitetos.
ANÁLISE DO SOMBREAMENTO PARCIAL DE UM SISTEMA FOTOVOLTAICO URBANO
Authors: David Chepp Ellen , Perin Gasparin Fabiano , Krenzinger Arno
Published: May 2023

Sistemas fotovoltaicos (FV) urbanos possuem, geralmente, muitos elementos no entorno, como construções vizinhas e vegetação, que podem causar sombreamento parcial na instalação FV. Em geral, não são estudados detalhadamente os efeitos desse tipo de sombreamento. Nesse contexto, o objetivo deste trabalho foi realizar uma análise detalhada dos efeitos do sombreamento parcial em um sistema FV instalado em Porto Alegre. Foram analisadas a potência e a tensão do sistema FV ao longo de um dia, utilizando fotos das sombras tiradas no local e a previsão de sombras de um modelo do SketchUp. Também foram simuladas curvas I-V utilizando dados de radiação solar e temperatura medidos. Foram analisadas as tensões individuais dos módulos FV ao longo de outro dia. Ao longo de um dia, foram verificadas reduções de potência durante a tarde (período do dia com sombreamento), que foram relacionadas a aumentos de tensão dos módulos. Assim que a sombra atingia um submódulo, o ponto de potência máxima (PPM) se deslocava para uma tensão menor, e o seguidor do ponto de potência máxima (SPPM) do inversor aumentava a tensão até um máximo e depois reduzia para tentar encontrar esse novo ponto. Após as 15h, a tensão do PPM ficou fora da faixa de operação do SPPM, e o sistema não era mais polarizado no PPM. A análise das tensões individuais confirmou esse comportamento. Cada vez que um submódulo era sombreado, a tensão de todos aumentava e depois reduzia. Então o submódulo sombreado era inversamente polarizado, de maneira que o diodo de desvio passava a conduzir corrente elétrica. As perdas por sombreamento poderiam ser reduzidas com o uso de um inversor com operação em tensões menores ou micro inversores neste caso estudado. Os efeitos de sombreamento abordados detalhadamente podem contribuir para um melhor entendimento do comportamento de outros casos de sombreamento parcial.
EQUIPAMIENTO SOLAR SUSTENTABLE PARA EL ESPACIO PUBLICO
Authors: Vera Luis , Pilar Claudia
Published: May 2023

En el presente artículo se exponen los resultados del diseño tecnológico, fabricación, montaje y evaluación de uso, de equipamientos solares sustentables para el espacio público. El objetivo general es el diseño de equipamientos alimentados con energía solar para promover el uso de las energías renovables en la comunidad. Para ello se diseñaron dispositivos tecnológicos estéticamente agradables, de bajo mantenimiento, alta durabilidad, con criterios de anti vandalismo, portables y de fácil montaje e instalación, materializados mediante componentes disponibles en el mercado regional. La hipótesis que guía este proyecto de investigación y desarrollo, es que para que la población acepte las energías renovables tiene que interactuar con ellas, por ejemplo, a partir de la satisfacción de necesidades cotidianas. Una alternativa válida para propiciar esa interacción son los equipamientos de uso público y comunitario, usando materiales disponibles en la región como ser el metal y la madera, e integrando en un solo dispositivo distintas funciones. Para el diseño se implementaron las premisas del Design Thinking (DT) en dos líneas de diseño: una fabricada en metal (denominada EUsolar) y otra en madera (denominada IRU). En ambos casos son Sistemas Fotovoltaicos Autónomos (SFA) con diseños de paradas de ómnibus, puestos de venta y cargadores solares.
El cargador solar de cada una de estas líneas se fabricó y montó en espacios públicos de la Región Nordeste Argentina (NEA), lo que permitió verificar los prototipos en condiciones reales de uso. Para conocer la percepción de los usuarios se realizó una encuesta anónima que dio por resultado una alta valoración de la iniciativa en cuanto a su utilidad, su estética y la aplicación de la energía renovable en equipamientos públicos.
ESTUDIO EXPERIMENTAL DE LECHO EMPACADO DE piedras A ALTA TEMPERATURA UTILIZANDO ESCORIA DE COBRE COMO MATERIAL DE ALMACENAMIENTO
Authors: Wolde Ian , Calderón-Vásquez Ignacio , Segovia A. Valentina , M. Cardemil José
Published: May 2023

El almacenamiento térmico ha mostrado ser altamente beneficioso al acoplarse a sistemas solares para la generación de calor y energía. Actualmente se utiliza en centrales eléctricas concentradas que utilizan sal fundida como material de almacenamiento, pero esta tecnología tiene inconvenientes considerables, ya que puede afectar el rendimiento de la planta. Se ha demostrado que el almacenamiento en lecho empacado utilizando aire como fluido de transferencia de calor es una alternativa competitiva, especialmente cuando se utilizan materiales de desecho industriales, lo que permite un alto rendimiento de almacenamiento. Este estudio considera una configuración experimental de un tanque horizontal lleno de escorias de cobre, que opera dentro del rango de temperatura media a alta, en un ciclo de carga-descarga. Los resultados muestran que la alta capacidad térmica de las escorias induce una alta inercia térmica y densidad de energía del tanque de almacenamiento, sin ningún inconveniente asociado con los altos gradientes térmicos.
Pemetaan Akuifer di Kelurahan Bakunase Kecamatan Kota Raja Kota Kupang dengan Metode Geolistrik Resistivitas
Authors: Theon Desi , Adelia Kadek A.C , Maubana Wenti M
Published: May 2023

Telah dilakukan pemetaan akuifer di Kelurahan Bakunase Kecamatan Kota Raja Kota Kupang dengan metode geolistrik resistivitas konfigurasi schlumberger. Penelitian bertujuan untuk mengetahui nilai resistivitas lapisan penyusun batuan di bawah permukaan dan mengetahui struktur bawah permukaan di daerah penelitian pada semua lintasan. Interpretasi  menggunakan software res2dinv dengan hasil interpretasi perlapisan batuan daerah penelitian terdiri dari lapisan lempung, alluvium dan gamping yang tersebar pada semua lintasan pengukuran. Berdasarkan lapisan batuan pada lokasi penelitian, batuan yang dianggap sebagai akuifer dangkal yaitu batuan alluvium yang terdapat pada kisaran kedalaman (6-13.4) m, dengan nilai resistivitas (38.2-65) ?m yang tersebar di lokasi pengukuran.
Rekayasa Genetik Tanaman Tomat Lokal Timor Dengan Metode Irradiasi Multigamma
Authors: Hunga Yuliana , Pasangka Bartholomeus , Tarigan Jonshon
Published: May 2023

Penelitian ini bertujuan mengembangkan tanaman tomat lokal dengan harapan dapat meningkatkan produksi dengan menentukan karateristik unggul tanaman tomat. Metode penelitian dilakukan dengan menerapkan radiasi sumber multigamma untuk mengetahui perubahan genotip dan fenotip dari dosis yang diterapkan. Hasil penelitian ini menunjukkan bahwa dosis yang tepat pada pengembangan tomat lokal Timor sekitar 2000 rads. Karateristik bakal unggul ini lebih baik dibandingkan dengan radiasi pada dosis 1000 rads, 2500 rads dan 3000 rads. Keunggulan dosis 2000 rads antara lain waktu tumbuh lebih cepat yaitu 4 hari setelah tanam, jumlah benih yang tumnbuh lebih banyak dan peningkatan produksi sebesar 95,92%.
Penentuan Konsentrasi Sulfat Dalam Air di Kelurahan Oeba Menggunakan Spektrotometer UV-VIS
Authors: Lesik Christian , Boimau Yanti , A.C Adelia Kadek
Published: May 2023

Telah dilakukan penelitian konsentrasi sulfat yang terkandung dalam air di Kelurahan Oeba. Penelitian ini dibatasi pada tiga lokasi yakni Sumur Tedens, Bak Penampung dan Sumur Penduduk. Sampel air dari ketiga lokasi tersebut kemudian dianalisa dengan menggunakan Spektrofotometer UV-Vis dengan metode turbiditas. Sebelum sampel dianalisa, terlebih dahulu dibuat larutan standar sulfat dengan konsentrasi 5ppm, 10ppm, 15ppm, 20ppm, dan 25ppm. Output serapan baik untuk larutan standar dan larutan sampel kemudian digunakan untuk memperoleh konsentrasi sulfat dalam air sampel berdasarkan persamaan regresi yang secara otomatis muncul dalam output. Berdasarkan perhitungan maka didapat konsentrasi sulfat 15,09ppm, 20,45ppm, dan 106,12ppm masing-masing untuk sampel air di Sumur Tedens,  Bak penampung dan Sumur Penduduk.
Penerapan Metode Geomagnetik Untuk Mengetahui Pola Perlapisan Batuan Bawah Permukaan Gunung Timau
Authors: Liukae Aidy , Tanesib Jehunias L. , Boimau Yanti
Published: May 2023

Telah dilakukan penelitian dengan pemodelan dua dimensi metode geomagnet pada wilayah Timau, Kecamatan Amfoang Tengah, Kabupaten Kupang. Penelitian ini bertujuan untuk mengidentifikasi jenis batuan bawah permukaan untuk mengetahui struktur perlapisan batuan dalam mendirikan bangunan observatorium di lokasi penelitian. Daerah penelitian dengan 40 titik ukur. Proses akusisi data dengan sistem looping menggunakan alat Proton Prosission Magnetometer (PPM) tipe GSM-19T. Data yang diperoleh di lapangan berupa nilai medan magnet total. Penentuan posisi titik ukur menggunakan Global Positioning Sistem (GPS). Pengolahan data diawali dengan koreksi variasi harian dan koreksi IGRF untuk mendapatkan anomali magnetik. Reduksi kontinuasi ke atas pada ketinggian 10 meter bertujuan untuk memisahkan anomali lokal dan anomali regional. Pemodelan dengan metode forward modeling menggunakan software Mag2DC for windows. Hasil interpretasi kualitatif diperoleh dua pola anomali, yaitu anomali sedang dengan rentang nilai 1 nT - 32 nT, dan anomali rendah dengan rentang nilai -60 nT-0 nT. Interpretasi kuantitatif menunjukan bahwa di lokasi terdapat dua jenis batuan, seperti batu pasir dengan suseptibilitas dimulai dari 0,000021-0,000993 cgs unit; batu gamping dengan suseptibilitas dimulai dari 0,000698-0,001161 cgs unit.
Investigasi Pergeseran Pusat Akumulasi Kandungan Radioisotop dalam Deposit Mineral oleh Proses Migrasi di Desa Oesu’u Kupang Timur
Authors: Tiro Veronika , Pasangka Bartholomeus , Tarigan Jonshon
Published: May 2023

Penelitian ini bertujuan untuk menganalisa pola penyebaran dan pergeseran pusat akumulasi kandungan radioisotop dalam deposit mineral oleh proses migrasi di DesaOesu’u, Kecamatan Kupang Timur, Nusa Tenggara Timur. Metode penelitian yang digunakan adalah metode survei radiometrik yang terdiri dari survei lokasi, pengukuran di lapangan, analisis data, dan interpretasi data. Hasil penelitian meliputi interval cacah radiasi pada daerah inti berada pada range 7 cpm sampai 61 cpm. Interpretasi data dilakukan pada peta kontur sebaran kandungan radioisotop dalam deposit mineral pada luas daerah kurang lebih 60 m x 250 m, ditemukan adanya penyebaran dan pergeseran kandungan radioisotope pada permukaan daerah target. Luas daerah yang terukur seluruhnya adalah 1500 m2. Akumulasi radioisotope dengan cacah radiasi tinggi dan cacah sedang sebagian besar terdapat di sebelah barat lokasi penelitian dengan luas daerah yang diduga berbahaya adalah sekitar 140 m2 dan di sebelah selatan lokasi penelitian dengan luas daerah yang diduga berbahaya adalah sekitar 80 m2. Total luas daerah yang berbahaya adalah sekitar 220 m2.
Identifikasi Potensi Reservoar Batupasir Menggunakan Atribut Seismik di Lapangan “Aru” Cekungan Jawa Barat Utara
Authors: Multi Warni , Arisalwadi Meidi
Published: May 2023

Telah dilakukan penilitian di Lapangan “Aru” yang merupakan lapangan migas di Cekungan Jawa Barat Utara. Penggunaan data konvensional untuk identifikasi potensi reservoar batupasir dan sebarannya di daerah penelitian masih kurang optimal sehingga analisa dilakukan menggunakan atribut RMS Amplitude. Penelitian bertujuan untuk mengidentifikasi sebaran reservoar batupasir yang berpotensi sebagai penyimpan hidrokarbon di daerah penelitian. Data yang digunakan adalah data seismik dan data sumur. Data seismik berupa data sekunder 3D pre-stack time migration (PSTM) yang terdiri atas 381 lintasan inline dan 859 crossline dengan sampling rate 2 ms. Digunakan pula empat data sumur yang dilengkapi properti fisik dan marker reservoar kajian. Pengolahan datanya diawali dengan pembuatan sintetik seismogram untuk menyamakan horizon seismik dalam skala waktu dari data seismik terhadap posisi kedalaman sebenarnya pada data sumur. Pembuatan time structure map untuk analisa struktur tinggian dan rendahan sebagai potensi jebakan hidrokarbon. Tahap akhir pengolahan yaitu analisa sebaran reservoar batupasir yang berpotensi menyimpan hidrokarbon melalui peta anomali atribut RMS amplitude. Hasil interpretasi time structure map dari penampang reservoar 39A dan 39C secara struktural menunjukkan sumur B1 dan A4 terletak pada area tinggian dengan nilai surface elevation yaitu -1175ms sampai -1025ms. Hasil ini dikorelasi dengan peta anomali atribut RMS amplitude dari penampang reservoar 39A dan 39C namun ditunjukkan bahwa hanya area sumur B1 yang memiliki kontras yang ekstrim terhadap anomali amplitudo tinggi dengan nilai -103 hingga -303 yang penyebarannya hingga ke arah Utara. Kontras anomali amplitudo tinggi ditafsirkan sebagai litologi batupasir terisi hidrokarbon. Hasil ini berkorelasi juga dengan well test sumur B1 yang terbukti mengandung hidrokarbon.
Kajian Awal Karakteristik Impedansi Listrik Larutan NaCl pada Berbagai Konsentrasi Menggunakan Metode Spektroskopi Impedansi Listrik
Authors: Sugianto Wahyu , Wismaya Herenda Sela
Published: May 2023

Larutan NaCl merupakan salah satu elektrolit utama dalam tubuh manusia. Selain itu, pemanfaatan larutan NaCl sebagai larutan pengencer pada bidang medis juga banyak digunakan. Makalah ini menganalisis karakteristik impedansi larutan NaCl dan juga hubungan antara konsentrasi dengan nilai impedansi listrik dari larutan NaCl. Metode Spektroskopi Impedansi Listrik (SIL) diterapkan dengan menginjeksikan arus listrik sebesar 1 mA ke dalam larutan NaCl. Tegangan keluaran respons dicatat menggunakan PicoScope 5244B. Pengukuran impedansi menggunakan dua elektroda jarum yang terbuat dari emas dalam rentang frekuensi 1 Hz hingga 100 kHz. Konsentrasi sampel larutan NaCl yang digunakan 1,7 mM- 513 mM. Karakteristik impedansi hasil pengukuran larutan NaCl memiliki pola seperti model rangkaian ekuivalen Randles. Pengukuran impedansi larutan NaCl yang baik adalah pada rentang frekuensi 10 kHz – 100 kHz dimana larutan NaCl memiliki sifat resistif yang dominan. Hasil pengukuran impedansi listrik dari Larutan NaCl semakin berkurang dengan bertambahnya konsentrasi larutan NaCl.
The effect of anticipated regret on flu vaccination campaigns
Authors: Marcatto Francesco , Detela Elisa , Ferrante Donatella
Published: May 2023

The anticipation of regret is known to be a primary motivator of receiving a vaccination. Aim of this study is to evaluate whether the use of messages that leverage the anticipated emotion of regret can increase the intention to get the flu vaccination. The participants (N = 110) randomly received a leaflet containing a standard prevention message (control condition) or message modified to induce the anticipation of regret over not being vaccinated (experimental condition), along with a questionnaire. The experimental condition’s participants reported significantly higher levels of regret and higher intention to vaccinate than the participants in the control condition. Anticipated regret resulted to be a significant mediator of the intention to get vaccinated. Manipulating the salience of regret appears to be a simple and inexpensive way of effectively promoting preventive behaviour. The implications of this result for reducing COVID-19 vaccine hesitation are discussed.
Investigating the Conflict Management Styles of Leadership in Secondary Schools through Structural Theory of Conflict
Authors: Dr. Zakiah Binte Noordin
Published: May 2023

Conflict exists in all kinds of work settings no matter how much you attempt to avoid it, if you work with people the chances are you will have to deal with conflict at some point. Conflict management has received much attention in the organizational literature in the recent past; because of a shift in attitudes toward conflict in organizations. This study focused on the conflict management styles of the principals of public and private sector schools. The study employed a survey; the population consisted of all the ‘secondary school principals of Bangi Selangor Malaysia. To test the instrument and determine sample size through formula, a pilot study was conducted, and the sample size was 154. For six research and four demographic variables, a 5-point Likert scale was used to record the responses. The study concluded that leadership should not suppress or resolve the conflict, but shall manage it in consultation with the supervisor and other employees. Since the principal’s conflict management styles affect the member’s behavior and eventually the organization’s performance. Therefore, different types of conflict management styles should be applied based on the appropriate situation, and that requires the ability of a manager to adapt their behavior according to the different situations to meet the needs. At the same time, trust is also an essential component that plays a role as the foundation of relationships, which is especially important when it comes to teamwork.
Promoting Human Rights standards for lesbian, gay, bisexual, and transgender people from the perspective of International law
Authors: Edison Thomas , Liu Chen , Hank Tom
Published: May 2023

This article examines the issue of how various religious and legal systems cope with current developments that weaken the binary opposition of men and women including their definitions of sexual identity and culture. More concretely, this book tries to explain how society and concrete laws deal with claims of lesbian, gay, bisexual, and transsexual (LGBT) who claim wider recognition. This explains the difference between the Western provisions and the policies of relevant legal bodies such as the General Assembly of the United Nations, the European Court of Human Rights, and the Supreme Court regarding this matter. This also shows the nature and real impact of international civil society forces such as the Yogyakarta principle which formulates the expansion of rights regarding lesbian, gay, bisexual, and transsexuals. Based on a comparison of various legal and religious discourses, he describes the current practice of direct and indirect discrimination and in some non-European national systems even extrajudicial killings, torture and ill-treatment, sexual assault, rape, and other human rights violations. While emphasizing the substantial differences between current European countries and non-European countries regarding policies towards lesbian, gay, bisexual, and transgender (LGBT), it points to the current trend of progress in the field by the general policy of the European Council, the most recent assessment issued by the European Court of Human Rights as well as civil society efforts such as the Yogyakarta principle. Swedish standards have been introduced to emphasize existing progressive attitudes towards LGBT people regarding gay marriage and adoption procedures.
THE UNIQUENESS OF TELEK DANCE IN JUMPAI VILLAGE
Authors: Pratiwi Ni Luh Putu Mirah , Permanamiarta Putu Agus
Published: May 2023

Telek dance in Village A is a guardian or sacred dance. The dance is still maintained from generation to generation, preserved and maintained. this dance is a heritage dance that must be performed by the residents of the village because local residents believe that the dance is a form of repellent to reinforcements in order to be given safety and keep village A away from the plague, the dance is performed once every 15 days which coincides with rahinan kajeng kliwon. The Telek dance in Jumpai village is estimated to have developed around 1935 until now. the Telek dance in there was performed by 4 male and female dancers who were still classified as children (approximately 6-12 years old). The purpose of this research is to show the value of function and meaning in Telek dance in village A. The values in Telek dance include; religious values, cultural values, knowledge values, and skills values. This dance is danced with a duration of 14 minutes.
Sanatorium and wellness environment of the city of Khabarovsk. Main development trends
Authors: Puzhkina Aleksandra Alekseevna , Kim Anton
Published: May 2023

The author examines the history of the development of the architecture of medical institutions and the principles of its placement in the planning structure of the city of Khabarovsk. The analysis of expansion and development of medical institutions of the city of Khabarovsk from the end of the XIX century to the present day is carried out. Numerous examples of buildings of medical institutions are given, showing the main stages of development of this type of structures in the locality under consideration. The author analyzes the change in stylistic and compositional preferences in the organization of medical and sanatorium institutions. The perspective ways of further transformation of the sanatorium system in the aspect of architectural and urban planning design, taking into account regional peculiarities, are analyzed. In the course of the work, the following trends in the design of sanatorium and rehabilitation centers in the city were identified: 1) large block organization of the building, the formation of complexes; 2) emphasis on the intensity of treatment, the use of day hospitals; 3) individualization of design solutions, rejection of stereotypical hospital forms; 4) the formation of a humane space with therapeutic potential; 5) ecological approach and harmony with the environment. A systematic and comprehensive analysis of the subject of the study also revealed the main requirements for the formation of such institutions, such as the development of functional zoning and planning organization, taking into account the features of functionally new departments of treatment rooms with complex equipment and numerous communications.
Prolonged nicotine exposure reduces aversion to the drug in mice by altering nicotinic transmission in the interpeduncular nucleus
Authors: Mondoloni Sarah , Nguyen Claire , Vicq Eléonore , Ciscato Maria , Jehl Joachim , Durand-de Cuttoli Romain , Torquet Nicolas , Tolu Stefania , Pons Stéphanie , Maskos Uwe , Marti Fabio , Faure Philippe , Mourot Alexandre
Published: May 2023

Nicotine intake is likely to result from a balance between the rewarding and aversive properties of the drug, yet the individual differences in neural activity that control aversion to nicotine and their adaptation during the addiction process remain largely unknown. Using a two-bottle choice experiment, we observed considerable heterogeneity in nicotine-drinking profiles in isogenic adult male mice, with about half of the mice persisting in nicotine consumption even at high concentrations, whereas the other half stopped consuming. We found that nicotine intake was negatively correlated with nicotine-evoked currents in the interpeduncular nucleus (IPN), and that prolonged exposure to nicotine, by weakening this response, decreased aversion to the drug, and hence boosted consumption. Lastly, using knock-out mice and local gene re-expression, we identified β4-containing nicotinic acetylcholine receptors of IPN neurons as molecular and cellular correlates of nicotine aversion. Collectively, our results identify the IPN as a substrate for individual variabilities and adaptations in nicotine consumption.
Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex
Authors: Kim Mean-Hwan , Radaelli Cristina , Thomsen Elliot R , Monet Deja , Chartrand Thomas , Jorstad Nikolas L , Mahoney Joseph T , Taormina Michael J , Long Brian , Baker Katherine , Bakken Trygve E , Campagnola Luke , Casper Tamara , Clark Michael , Dee Nick , D'Orazi Florence , Gamlin Clare , Kalmbach Brian E , Kebede Sara , Lee Brian R , Ng Lindsay , Trinh Jessica , Cobbs Charles , Gwinn Ryder P , Keene C Dirk , Ko Andrew L , Ojemann Jeffrey G , Silbergeld Daniel L , Sorensen Staci A , Berg Jim , Smith Kimberly A , Nicovich Philip R , Jarsky Tim , Zeng Hongkui , Ting Jonathan T , Levi Boaz P , Lein Ed
Published: May 2023

Rodent studies have demonstrated that synaptic dynamics from excitatory to inhibitory neuron types are often dependent on the target cell type. However, these target cell-specific properties have not been well investigated in human cortex, where there are major technical challenges in reliably obtaining healthy tissue, conducting multiple patch-clamp recordings on inhibitory cell types, and identifying those cell types. Here, we take advantage of newly developed methods for human neurosurgical tissue analysis with multiple patch-clamp recordings, post-hoc fluorescent in situ hybridization (FISH), machine learning-based cell type classification and prospective GABAergic AAV-based labeling to investigate synaptic properties between pyramidal neurons and PVALB- vs. SST-positive interneurons. We find that there are robust molecular differences in synapse-associated genes between these neuron types, and that individual presynaptic pyramidal neurons evoke postsynaptic responses with heterogeneous synaptic dynamics in different postsynaptic cell types. Using molecular identification with FISH and classifiers based on transcriptomically identified PVALB neurons analyzed by Patch-seq, we find that PVALB neurons typically show depressing synaptic characteristics, whereas other interneuron types including SST-positive neurons show facilitating characteristics. Together, these data support the existence of target cell-specific synaptic properties in human cortex that are similar to rodent, thereby indicating evolutionary conservation of local circuit connectivity motifs from excitatory to inhibitory neurons and their synaptic dynamics.
Global analysis of contact-dependent human-to-mouse intercellular mRNA and lncRNA transfer in cell culture
Authors: Dasgupta Sandipan , Dayagi Daniella Y , Haimovich Gal , Wyler Emanuel , Olender Tsviya , Singer Robert H , Landthaler Markus , Gerst Jeffrey E
Published: May 2023

Full-length mRNAs transfer between adjacent mammalian cells via direct cell-to-cell connections called tunneling nanotubes (TNTs). However, the extent of mRNA transfer at the transcriptome-wide level (the ‘transferome’) is unknown. Here, we analyzed the transferome in an in vitro human-mouse cell co-culture model using RNA-sequencing. We found that mRNA transfer is non-selective, prevalent across the human transcriptome, and that the amount of transfer to mouse embryonic fibroblasts (MEFs) strongly correlates with the endogenous level of gene expression in donor human breast cancer cells. Typically,<1% of endogenous mRNAs undergo transfer. Non-selective, expression-dependent RNA transfer was further validated using synthetic reporters. RNA transfer appears contact-dependent via TNTs, as exemplified for several mRNAs. Notably, significant differential changes in the native MEF transcriptome were observed in response to co-culture, including the upregulation of multiple cancer and cancer-associated fibroblast-related genes and pathways. Together, these results lead us to suggest that TNT-mediated RNA transfer could be a phenomenon of physiological importance under both normal and pathogenic conditions.
Improved isolation of extracellular vesicles by removal of both free proteins and lipoproteins
Authors: Ter-Ovanesyan Dmitry , Gilboa Tal , Budnik Bogdan , Nikitina Adele , Whiteman Sara , Lazarovits Roey , Trieu Wendy , Kalish David , Church George M , Walt David R
Published: May 2023

Extracellular vesicles (EVs) are released by all cells into biofluids such as plasma. The separation of EVs from highly abundant free proteins and similarly sized lipoproteins remains technically challenging. We developed a digital ELISA assay based on Single Molecule Array (Simoa) technology for ApoB-100, the protein component of several lipoproteins. Combining this ApoB-100 assay with previously developed Simoa assays for albumin and three tetraspanin proteins found on EVs (Ter-Ovanesyan, Norman et al., 2021), we were able to measure the separation of EVs from both lipoproteins and free proteins. We used these five assays to compare EV separation from lipoproteins using size exclusion chromatography with resins containing different pore sizes. We also developed improved methods for EV isolation based on combining several types of chromatography resins in the same column. We present a simple approach to quantitatively measure the main impurities of EV isolation in plasma and apply this approach to develop novel methods for enriching EVs from human plasma. These methods will enable applications where high-purity EVs are required to both understand EV biology and profile EVs for biomarker discovery.
Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster
Authors: Port Julia R. , Morris Dylan H. , Riopelle Jade C. , Yinda Claude Kwe , Avanzato Victoria A. , Holbrook Myndi G. , Bushmaker Trenton , Schulz Jonathan E. , Saturday Taylor A. , Barbian Kent , Russell Colin A. , Perry-Gottschalk Rose , Shaia Carl I. , Martens Craig , Lloyd-Smith James O. , Fischer Robert J. , Munster Vincent J.
Published: May 2023

It remains poorly understood how SARS-CoV-2 infection influences the physiological host factors important for aerosol transmission. We assessed breathing pattern, exhaled droplets, and infectious virus after infection with Alpha and Delta variants of concern (VOC) in the Syrian hamster. Both VOCs displayed a confined window of detectable airborne virus (24h - 48h), shorter than compared to oropharyngeal swabs. The loss of airborne shedding was linked to airway constriction resulting in a decrease of fine aerosols produced. Male sex was associated with increased viral replication and virus shedding in the air, including a VOC-independent particle-profile shift towards smaller droplets. Transmission efficiency varied among donors, including a superspreading event. Co-infection with VOCs only occurred when both viruses were shed by the same donor during an increased exposure timeframe. This highlights that assessment of host and virus factors resulting in a differential exhaled particle profile is critical for understanding airborne transmission.
Replisome loading reduces chromatin motion independent of DNA synthesis
Authors: Pabba Maruthi K. , Ritter Christian , Chagin Vadim O. , Stear Jeffrey H. , Loerke Dinah , Kolobynina Ksenia , Prorok Paulina , Schmid Alice Kristin , Leonhardt Heinrich , Rohr Karl , Cardoso M. Cristina
Published: May 2023

Chromatin has been shown to undergo diffusional motion, which is affected during gene transcription by RNA polymerase activity. However, the relationship between chromatin mobility and other genomic processes remains unclear. Hence, we set out to label the DNA directly in a sequence unbiased manner and followed labeled chromatin dynamics in interphase human cells expressing GFP-tagged PCNA, a cell cycle marker and core component of the DNA replication machinery. We detected decreased chromatin mobility during the S-phase compared to G1 and G2 phases using automated particle tracking. To gain insight into the dynamical organization of the genome during DNA replication, we determined labeled chromatin domain sizes and analyzed their motion in replicating cells. By correlating chromatin mobility proximal to the active sites of DNA synthesis, we showed that chromatin motion was locally constrained at the sites of DNA replication. Furthermore, inhibiting DNA synthesis led to increased loading of DNA polymerases. This was accompanied by accumulation of the single-stranded DNA binding protein on the chromatin and activation of DNA helicases further restricting local chromatin motion. We, therefore, propose that it is the loading of replisomes but not their catalytic activity that reduces the dynamics of replicating chromatin segments in the S-phase as well as their accessibility and probability of interactions with other genomic regions.– Direct and sequence unbiased labeling of DNA genome-wide– DNA labeled chromatin is more mobile in G1/G2 relative to the S-phase– Restriction of chromatin motion occurs proximal to sites of DNA replication– Loading of replisomes, even in the absence of processive DNA synthesis, restricts chromatin motion
Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS
Authors: Stener-Victorin Elisabet , Eriksson Gustaw , Mohan Shrestha Man , Rodriguez Paris Valentina , Lu Haojiang , Banks Jasmine , Samad Manisha , Perian Charlène , Jude Baptiste , Engman Viktor , Boi Roberto , Nilsson Emma , Ling Charlotte , Nyström Jenny , Wernstedt Asterholm Ingrid , Turner Nigel , Lanner Johanna , Benrick Anna
Published: May 2023

Background:

Polycystic ovary syndrome’s (PCOS) main feature is hyperandrogenism, which is linked to a higher risk of metabolic disorders. Gene expression analyses in adipose tissue and skeletal muscle reveal dysregulated metabolic pathways in women with PCOS, but these differences do not necessarily lead to changes in protein levels and biological function.

Methods:

To advance our understanding of the molecular alterations in PCOS, we performed global proteomic and phosphorylation site analysis using tandem mass spectrometry, and analyzed gene expression and methylation. Adipose tissue and skeletal muscle were collected at baseline from 10 women with and without PCOS, and in women with PCOS after 5 weeks of treatment with electrical stimulation.

Results:

Perilipin-1, a protein that typically coats the surface of lipid droplets in adipocytes, was increased whereas proteins involved in muscle contraction and type I muscle fiber function were downregulated in PCOS muscle. Proteins in the thick and thin filaments had many altered phosphorylation sites, indicating differences in protein activity and function. A mouse model was used to corroborate that androgen exposure leads to a shift in muscle fiber type in controls but not in skeletal muscle-specific androgen receptor knockout mice. The upregulated proteins in muscle post treatment were enriched in pathways involved in extracellular matrix organization and wound healing, which may reflect a protective adaptation to repeated contractions and tissue damage due to needling. A similar, albeit less pronounced, upregulation in extracellular matrix organization pathways was also seen in adipose tissue.

Conclusions:

Our results suggest that hyperandrogenic women with PCOS have higher levels of extra-myocellular lipids and fewer oxidative insulin-sensitive type I muscle fibers. These could be key factors leading to insulin resistance in PCOS muscle while electric stimulation-induced tissue remodeling may be protective.

Funding:

Swedish Research Council (2020-02485, 2022-00550, 2020-01463), Novo Nordisk Foundation (NNF22OC0072904), and IngaBritt and Arne Lundberg Foundation. Clinical trial number NTC01457209.
History of Various Classifications of Gastritis
Authors: Yim Sung Kyun , Seo Seung Young
Published: May 2023

Gastritis is common worldwide. The combination of Helicobacter pylori (H. pylori) infection with background gastritis, including atrophic gastritis or intestinal metaplasia is implicated as an important etiopathogenetic contributor to gastric cancer. Since the gastritis classification proposed by Schindler, research has focused on classification of gastritis for accurate diagnosis and prediction of prognosis. Advances in endoscopic technology have enabled more accurate visualization of the gastric mucosa and ‘targeted’ biopsies with the emergence of newer classifications based on visual findings (Kimura-Takemoto classification) and more specific histopathological findings using targeted biopsies (Whitehead classification). Following the discovery of H. pylori, it is mandatory to consider its role as an important contributor to gastritis. Therefore, it was necessary to redefine the classification of gastritis and arrive at a consensus, which led to the establishment of an international consensus classification, referred to as the Sydney system. However, the Sydney system alone cannot predict the gastric cancer risk, and scoring systems such as the Operative Link for Gastritis Assessment and the Operative Link on Gastritis Assessment based on Intestinal Metaplasia were proposed. These systems are based on histopathological findings observed in endoscopic biopsy specimens. However, availability of high-definition images following technological advances has facilitated the emergence of a visual classification, the Kyoto classification. In contrast to the Sydney system, the Kyoto classification is based exclusively on interpretation of visual findings and focuses on detection of H. pylori infection and gastric cancer prediction. In this review, we summarize the history and background of the various classifications of gastritis.
Takayasu's Arteritis with Aortic Insufficiency as Initial Presentation: A Case Report
Authors: Tahir A. Fadoul , Badaoui K. , Boucetta A. , Abouradi S. , Assklou A. , Haboub M. , Arous S. , Bennouna M. G. , Drighil A. , Azzouzi L. , Habbal R.
Published: May 2023

Takayasu's disease is the first cause of inflammatory aortitis in young subjects. The disease preferentially affects the women. Takayasu's disease could be a mode of non-specific reaction of the aorta to various infectious or dysimmune etiological factors.  Aortic insufficiency is present in 7 to 10% of cases. It is usually moderate. Its mechanism is not unambiguous: direct damage to the aortic valves or dilation of the aortic annulus. Coronary damage responsible for angina or even myocardial infarction are also possible. We report the case of a severe aortic insufficiency secondary to takayasu disease complicated by acute coronary syndrome in a 42-year-old woman.
Response of Bottle Gourd (Lagenaria siceraria (Mol.) Standl.) to Integrated Nutrient Management
Authors: Pathak Menka , Dash Sunil Kumar , Sahu Gouri Shankar , Tripathy Pradyumna , Mohanty Simanta , Nayak Rabindra Kumar , Mishra Antaryami
Published: May 2023

A field experiment was conducted during Kharif 2019 at, All India Co-ordinate Research Project, (AICRP), College of Agriculture, Odisha University of Agricultural and Technology (OUAT).The experiment consisted of twelve treatments with three replications evaluated in randomized block design. Results of field experiment revealed that the minimum days to seed germination (7.00days), maximum vine length (49.8, 187.7, 285.95 cm at 30, 60, 75 DAS, number of branches (6.18, 7.43, 8.12) at 30, 60, 75 DAS, leaf length (22.87cm), leaf width ( 21.76cm), leaf weight (48.14g), stem diameter (2.77cm), number of nodes on main vine (42.12), node bearing 1st male flower (4.16), node bearing 1st female flower (6.87), fresh wt. of fruit (1231g), dry wt. of fruit (48.75g), no. of seeds fruit-1 (448), fruit yield (28.01 q ha-1) was recorded with treatment 50%RDF+ FYM @ 7.5t ha-1+VC @ 2.5 t ha-1+ biofertilizer Consortia (T12) and minimum under control (T1).