bluuebunny/crossref_metadata_2025 huggingface dataset:
New trends in AA amyloidosis with renal involvement: a single-center experience
Authors: Marques Nídia , Oliveira-Silva Catarina , Pinho Ana , Nunes Ana Teresa , Sampaio Susana , Oliveira Ana , Tavares Isabel
Published: February 2025

Abstract Introduction: In the northwest of Portugal, AA amyloidosis was reported as the most frequent amyloid nephropathy, but it is unclear if the disease’s incidence and outcomes have changed. The authors studied the changing epidemiology, aetiologies, and outcomes of patients with renal AA amyloidosis over the last 40 years. Methods: This is a retrospective single-center cohort study involving patients with renal biopsy-proven AA amyloidosis diagnosed in the northwest of Portugal between 1978 and 2019. The patients were grouped into 14-year cohorts based on the year of diagnosis (CA 1978–1991; CB 1992–2005; CC 2006–2019), and clinical course and outcomes were analyzed. Results: Sixty-nine AA amyloidosis patients were included. The incidence of the disease remained stable in CA (64%) and CB (62.7%) as opposed to the significant decrease in the most recent cohort (44%, p = 0.027). The mean age at presentation increased by ten years from CA to CC. Overall, infections were the leading cause of death, with a significant rise over time (9.1% in CA to 76.9% at CC, p = 0.002). There were no significant global and renal survival differences between the three cohorts. However, the CC patients died at an older age (61.4 years) than the CA (52.3 years). Conclusion: The incidence of AA amyloidosis has been declining over the last 40 years. In contrast, the age at presentation of amyloid nephropathy has been increasing. Global and renal outcomes did not improve, but the average life expectancy increased, suggesting progress in general management and supportive care of renal and underlying pathology.
Complicações imediatas na retirada de introdutor vascular femoral: estudo transversal
Authors: Silveira Carolina Galli da , Almeida Graziela Maria Ferraz de , Avila Marla Andréia Garcia de , Teixeira Tatiane Roberta Fernandes , Lima Fernanda Maria Alves
Published: February 2025

Resumo Objetivo verificar a prevalência de complicações imediatas na retirada de introdutores vasculares femorais por enfermeiros e os principais fatores associados à sua ocorrência. Método estudo transversal que incluiu 1.281 pacientes submetidos aos procedimentos endovasculares por via femoral e tiveram o introdutor vascular retirado por enfermeiros de um Serviço de Hemodinâmica, no período de janeiro de 2018 a dezembro de 2020. Os fatores associados à complicação vascular foram investigados por associação bivariada e regressão linear múltipla com resposta Poisson, com o nível de significância de 5% (p<0,05). Resultados a prevalência de complicações vasculares foi de 16,8% (n=215). A principal complicação foi a ocorrência de hematoma. A retirada de introdutor vascular femoral com a compressão do tipo mista (p=0,050) e do tipo mecânica (p<0,001), o maior tempo de compressão (p<0,001) e a presença de agitação psicomotora (p=0,040) se associaram ao surgimento de hematoma. Conclusão e implicações para a prática foi identificada a principal complicação vascular na retirada de introdutores vasculares femorais e fatores associados. Os achados podem auxiliar no aprimoramento da prática assistencial de retirada de introdutores vasculares, na busca de uma execução da técnica com maior qualidade e em um procedimento mais seguro ao paciente, além de permitir a implementação de medidas preventivas adequadas.
Desvantagem, fadiga vocal e qualidade de vida em voz em pacientes com Esclerose Múltipla
Authors: Santiago Raí dos Santos , Araújo Jaya Miranda Carvalho de , Nascimento Márcia Helena Cassago , Anhoque Carolina Fiorin , Neves Alana Tagarro , Depolli Gabriel Trevizani , Castrillo Bruno Batitucci , Dias Paula Zago Melo , Vanzo Regina Eliza Albano , Nascimento Carla Carvalho , Barauna Valerio Garrone , Rodrigues Lívia Carla de Melo
Published: February 2025

RESUMO Objetivo descrever características sociodemográficas de indivíduos com esclerose múltipla, correlacionar e comparar a fadiga, desvantagem vocal e a qualidade de vida em voz de indivíduos com e sem a doença. Método Estudo transversal, quantitativo e com 52 voluntários com esclerose múltipla e 52 voluntários-controle, pareados por sexo, idade e escolaridade. Dados sociodemográficos e clínicos foram coletados com questionário e análise de prontuários. Os participantes responderam ao Índice de Desvantagem Vocal reduzido (IDV-10), Índice de Fadiga Vocal (IFV) e Qualidade de Vida em Voz (QVV). Análises correlacionais e comparativas foram realizadas, com um nível de significância de 5% (p<0,05). Resultado Maior predomínio de participantes diagnosticados com esclerose múltipla do sexo feminino, média de 40 anos, ensino médio completo e curso da doença do tipo remitente-recorrente. Houve correlação positiva entre a desvantagem e a fadiga vocal, e correlação negativa entre a desvantagem e fadiga vocal com a qualidade de vida em voz em ambos os grupos. Além disso, os participantes com esclerose múltipla ultrapassaram as notas de corte do IDV-10 e do IFV e ficaram abaixo da nota de corte do QVV. Conclusão Houve prevalência da doença em indivíduos jovens do sexo feminino, escolarizados e do tipo remitente-recorrente. Quanto maior a desvantagem e/ou a fadiga vocal, menor é a qualidade de vida em voz em ambos os grupos. No entanto, pessoas com esclerose múltipla autorreferem maior desvantagem e fadiga vocal, além de menor qualidade de vida relacionada à voz.
Sistema vestibulococlear e qualidade de vida de musicistas: um estudo acerca dos efeitos da exposição sonora
Authors: Scheuer Magali , Pimentel Bianca Nunes , Martins Priscilla dos Santos , Moreira Hélinton Goulart , Santos Filha Valdete Alves Valentins dos
Published: February 2025

RESUMO Objetivo Avaliar e comparar os efeitos da exposição sonora no sistema vestíbulococlear entre os grupos e a qualidade de vida dos musicistas. Método Participaram 56 indivíduos, sendo 28 musicistas e 28 não-musicistas, com faixa etária de 18 a 45 anos e de ambos os sexos. Os participantes foram submetidos à anamnese, avaliação audiológica básica, potencial evocado miogênico vestibular (VEMP) e, exclusivamente, os musicistas ao questionário WHOQOL-Bref. Resultados Participaram musicistas profissionais e entusiastas que apresentaram limiares auditivos aumentados nas frequências de 3 e 4KHz e qualidade de vida consideravelmente satisfatória. Houve significância nas latências do VEMP cervical e na latência da onda P15 do lado esquerdo do VEMP ocular do grupo estudo em relação ao grupo controle. O VEMP demonstrou ondas maiores bilateralmente nos homens em comparação com as mulheres. Conclusão Concluiu-se que a exposição sonora, dentro dos limites de tolerância em tempo e intensidade, foi passível de proporcionar benefícios auditivos, vestibulares e de qualidade de vida para os musicistas.
BIG DATA ANALYTICS-ARTIFICIAL INTELLIGENCE, AMBIDEXTERITY, AND GREEN SUPPLY CHAIN MANAGEMENT: IMPLICATIONS ON RESPONSIBLE ECONOMY
Authors: Wang Shanshan , Jia Chenge , Khan Asif , Khan Naila Habib , Hsieh Chia-Hung , Hung Chung-Wen , Chen Shih-Chih
Published: February 2025

ABSTRACT In the current dynamic market, businesses have recognized the pivotal role of data and sustainability technologies in attaining competitive advantage. Big Data Analytics-Artificial Intelligence and Green Supply Chain Management are significant sustainability promotion strategies. The research collected data from 220 employees in the Taiwanese manufacturing sector with the help of a survey methodology. The findings revealed significant impacts of Big Data Analytics-Artificial Intelligence on both green supply chain management and supply chain ambidexterity. Moreover, supply chain ambidexterity significantly influences green supply chain management. Lastly, supply chain ambidexterity was also found to mediate the relationship between Big Data Analytics-Artificial Intelligence and green supply chain management. This study provides several implications for fostering a responsible economy. It elucidates how leveraging Big Data Analytics-Artificial Intelligence enhances supply chain ambidexterity, reinforcing sustainable practices without detectable alterations.
Effect of heat treatment on microstructure and properties of a new low-cost Ti-5Al-1.5Mo-1.8Fe alloy
Authors: Xu Qinsi , Hu Jinbao , Yao Nan , Li Shujun , Mu Yiqiang , Lei Xiaofei
Published: February 2025

A new low-cost titanium Ti-5Al-1.5Mo-1.8Fe alloy has been developed. The different solid solution temperatures and cooling rates as well as deformations effect on microstructure and mechanical properties of this alloy were studied. The results have shown that the alloy exhibits a lamellar α + β microstructure after undergoing solid solution and aging treatment, leading to a significant increase in strength. Specifically, the alloy with forging deformation of 20% shows the highest strength after heat treatment, and the yield strength and tensile strength are 950 MPa and 1100 MPa, respectively. Moreover, different cooling rates, such as water quenching and air cooling, can yield diverse morphologies of α + β microstructures. Specifically, water quenching leads to the formation of a lamellar structure comprising acicular martensite α. Notably, the mechanical properties of this new low-cost alloy are influenced by the cooling rate. Higher strength is achieved through faster cooling rates, with the yield and tensile strengths being 1040 MPa and 1150 MPa, respectively.
Efficiency of dry salt baths and magnetic-laser exposure in the rehabilitation treatment of patients with chronic prostatitis
Authors: Gilmutdinov B.R. , Pavlov V.N. , Gilmutdinov A.R. , Gilmutdinova L.T. , Khasanov A.G. , Yamaletdinov K.S. , Markosyan T.G. , Faizova E.R.
Published: February 2025

Objective. To evaluate the efficiency of treatment complexes based on magnetic-laser therapy with electrical stimulation and dry salt baths in the rehabilitation treatment of patients with chronic prostatitis. Material and methods. There have been observed 74 men with chronic abacterial prostatitis at the age of 34—46 years old. The patients were divided into groups using the simple randomization method depending on the therapy. The patients of the main group (n=25) were prescribed procedures of dry salt baths in combination with magnetic-laser exposure and electrical stimulation on a physiotherapeutic software complex according to the developed method in addition to the basic complex. The patients of the group of comparison (n=25) were prescribed dry salt baths against the background of the basic complex according to the developed method. The patients of the control group (n=24) had a basic complex that included therapeutic gymnastics, microclysters with decoction of medicinal herbs, vibration massage of the prostate gland, therapeutic nutrition, drinking mineral water, therapeutic walking and climate therapy. The course of rehabilitation treatment was 18 days. Results. It was found that the patients of the main group improved indices of regional hemodynamics, echographic picture, functional state of the prostate gland, psychoemotional status of the patients and reduced significantly the severity of pain syndrome after the course of rehabilitation treatment with less significant dynamics of similar parameters in the compared group, while maintaining the results in the long term, in contrast to the control group. Conclusion. The inclusion of the combined use of dry salt baths and magnetic-laser exposure with electrical stimulation according to the developed method in the complex of rehabilitation treatment of patients with chronic prostatitis significantly increases the effectiveness while maintaining the results in the long term.
The influence of neurofeedback on the β-rhythm of the brain on the characteristics of attention in athletes with different training orientations
Authors: Lunina N.V. , Koryagina Yu.V. , Nopina V.S. , Iosipchuk K.O. , Tishkova M.H. , Illarionov V.E. , Gazaeva Z.M.
Published: February 2025

Modern scientific research has shown that neurofeedback optimizes the functioning of the nervous system as a whole, increases the efficiency and productivity of various types of activities. In clinical practice, neurofeedback based on the β-rhythm of the brain has been effective in correcting conditions associated with decreased attention, promoting concentration and behavioral improvements. However, the influence of neurofeedback on the β-rhythm of the brain on the attention processes of athletes with different training orientations has not yet been sufficiently studied. Objective. Studying the effect of neurofeedback on the β-rhythm of the brain on the characteristics of attention in athletes with different training orientations. Material and methods. The study involved male athletes aged 18—22 years old, divided into 5 groups by sport and a comparison group. The course of neurofeedback on the β-rhythm of the brain consisted of 10 sessions, including graphic and game sessions, in which it was necessary to select a strategy for raising the β-rhythm of the brain during muscle relaxation, implemented under conditions of visual and auditory biofeedback. The characteristics of attention were studied using the Schulte method. Results. The initial values of the studied characteristics of attention in the comparison group (CG) did not have reliably significant differences with similar indicators in the studied groups of athletes with different training orientations. Analysis of the dynamics of attention indicators in the GS showed a tendency, without significant changes, to improve the efficiency of attention (EA) and the total time of work in the test. A course of neurofeedback based on the β-rhythm of the brain contributed to the improvement of attention characteristics in athletes, depending on the direction of the training process. EA increased to a high level in young men of cyclic, game, complex-coordination sports and among martial artists, and in athletes of speed-strength sports — to a level above average. Athletes of all studied groups who completed the course of β-training increased the speed of development with consistently high values in representatives of cyclic sports, in almost all groups the stability of attention increased to a high level (p≤0.05), with the best values in the coordination sports, among team sports athletes the indicator reached an average level. Conclusion. Optimization of attention characteristics when using neurofeedback according to the β-rhythm of the brain in athletes is specific depending on the direction of the training process, and in total leads to a significant improvement in the studied indicators.
The long-term observation period of pregnant women after acute gestational pyelonephritis
Authors: Fedorov A.A. , Gaitova M.R. , Franc M.A. , Telegina E.V. , Dzyubinskaya E.V. , Efimenko N.V. , Chalaya E.N. , Zhumanova E.N. , Moiseev V.V.
Published: February 2025

Urinary tract infections, in particular acute gestational pyelonephritis (AGP) determine a high risk of developing various complications of pregnancy and childbirth. The development of new medical technologies for the treatment of AGP remains relevant. It has not only high direct effectiveness, but also shows a distinct impact of secondary prevention of pyelonephritis exacerbations and a fetoprotective effect. An objective evidence for these effects is the study of long-term treatment outcomes. Objective. To evaluate the general condition of pregnant women in a randomized controlled study of the long-term observation period who underwent acute gestational pyelonephritis, birth results, quality of life of the patients and vitality of the newborns. Material and methods. The study included 93 women at the age of 16 to 40 years old who underwent AGP. They were divided into two groups by simple randomization: the main/MG (46 people) and the control/CG (47 people). The control group of the patients was prescribed the drug standard; the main one had intravenous ozone therapy (OT) in addition to it. Results. In the MG the patients had significant differences (p<0.05—0.001) with women of the CG in such indicators as: repeated relapses of gestational pyelonephritis (4.5 times), late gestational toxicosis (2.6 times), the number of newborns with normal growth and weight parameters (1.9 times), bacteriuria (3.0 times), leukocytouria (4.0 times), medical care for the main disease (5.0 times), outpatient treatment (8.0 times) and quality of life indicators — physical and social activity as well as general health. Conclusion. An additional prescription in the standard of care for patients with AGP based on intravenous administration of an ozone-oxygen mixture significantly improves the long-term results of the therapy and the quality of life of patients who have undergone AGP, and also has a distinct fetoprotective effect. The absence of adverse reactions with all the patients including in the long-term follow-up period indicates the safety of a new complex of restorative treatment for AGP.
Hybrid wound coating in rehabilitation of severe thermal burns. (An experimental study)
Authors: Markov P.A. , Eremin P.S. , Vinogradov I.I. , Nechaev A.N. , Rozhkova E.A. , Marchenkova L.A. , Gilmutdinova I.R. , Knyazeva T.A. , Eremin I.I.
Published: February 2025

One of the tasks of restorative medicine is the rehabilitation of the body that has suffered from injuries, diseases or adverse environmental effects, and the restoration of the functional reserves of the human body. Currently, a search is underway for new treatment technologies, including the use of wound dressings with specified functional qualities. Objective. To characterize the effect of a wound dressing based on an ion-track membrane modified with collagen and chitosan nanofibers on the efficiency of skin restoration in experimental animals after a severe thermal burn. Material and methods. Polyethylene terephthalate film perforated with heavy metal ions (Xe, Kr) on a nuclear particle accelerator was used as a base. The biopolymer layer was applied from the solution using electrospinning. Thermal (120° C, 60 min) treatment was used to stabilize the biolayer. Using light and fluorescence microscopy, the morphometric characteristics of the cells were assessed, and flow cytometry and commercial kits were used to evaluate the expression of cell differentiation markers (CD16, CD14, CD163, CD206). Modeling of a severe thermal burn was performed on laboratory rats. Results. The main structural element of the biolayer is spontaneously intertwined fibers, 170±40 nm thick. The results of studies conducted in vitro using fibroblasts and monocytic cells of human peripheral blood allow us to draw the following conclusion: the hybrid biomaterial BioTM has qualities that meet the requirements for wound dressings, namely gas permeability, biocompatibility and the ability to inhibit immune-inflammatory cellular reactions. In vivo, it was shown that the hybrid biomaterial BioTM promotes skin restoration in experimental rats after thermal injury. Moreover, the effectiveness of the BioTM biomaterial exceeds therapy using Levomekol ointment. Conclusions. Thus, based on the results obtained, the following conclusion can be made: the wound coating based on the track membrane and the biocomposite layer inhibits spontaneous activation of monocytes and their differentiation into a proinflammatory phenotype. When integrating the bioplastic material with the synthetic membrane, the functional properties of both types of materials are preserved, which makes it possible to obtain a new type of wound coating with a high regenerative potential that exceeds the effectiveness of traditional burn therapy.
El diálogo y la paz. Mi perspectiva
Authors: Vélez de Piedrahíta Rocío
Published: February 2025

Rocío Vélez de Piedrahíta participó con gran dedicación como comisionada en el proceso de paz impulsado por Belisario Betancur entre 1982 y 1986. En su relato, que se mueve entre lo jocoso, lo desconcertante y lo triste, Vélez describe la complejidad y la audacia de un proceso que comenzó con mucho entusiasmo, gracias a la personalidad del presidente, pero en el que se fue perdiendo confianza progresivamente a causa de la violencia entre los actores involucrados. Esta obra, publicada por primera vez en 1988, ofrece detalles reveladores sobre el papel de los comisionados, los guerrilleros, los militares, los políticos y otros actores clave, además de incluir anécdotas, testimonios de campesinos víctimas de la violencia y una reflexión sobre el impacto de la toma del Palacio de Justicia. Esta edición incluye un prólogo escrito por el académico Jorge Giraldo Ramírez, infografías, fotografías tomadas por la autora y el discurso de lanzamiento de la primera edición. Para Rocío Vélez, el proceso no debe ser visto únicamente como un diálogo fracasado que no logró desmovilizar a los grupos guerrilleros, sino como la implementación de un conjunto de reformas bien equilibradas que se llevaban a cabo desde diferentes frentes. Mientras la Comisión de Paz propiciaba la tregua, otros en las subcomisiones estudiaban reformas urgentes en educación, salud, servicios públicos, justicia, en la Constitución y en los ámbitos agrario y urbano, con el fin de presentarlas al Congreso. Simultáneamente, se puso en marcha el Plan Nacional de Rehabilitación (PNR), que continuó ejecutándose durante el gobierno de Virgilio Barco.

En esta obra, Rocío Vélez revela detalles significativos sobre el papel de los comisionados, los líderes de los diferentes grupos guerrilleros, los militares, los partidos políticos, los congresistas, la Iglesia, la prensa y los ciudadanos. Asimismo, comparte, entre muchas otras vivencias, anécdotas de sus visitas a La Uribe y testimonios desgarradores de campesinos víctimas de la violencia, y describe los efectos que la toma del Palacio de Justicia tuvo en el proceso. Esta edición se acompaña de un prólogo escrito por Jorge Giraldo, infografías explicativas, el discurso de lanzamiento de la edición de 1988 y fotografías tomadas por la autora.
Análise comparativa entre aderência à tração e resistência à compressão em argamassas produzidas com vermiculita expandida
Authors: Affonso Stella Bruna Ananias , Alves Edson , Azambuja Maximiliano dos Anjos
Published: February 2025

In the construction industry, the performance of building elements is a pertinent topic for scientific research. Sustainability and concern for non-renewable natural resources have stimulated the search for alternative materials that have the potential to improve the properties of cement mortars. Although it is a material that is still rarely used as an aggregate in mortars, expanded vermiculite has interesting properties, with the potential to replace natural sand, reducing the environmental impact caused by its extraction. The aim of this study was to analyze, based on physical and mechanical characteristics, the reduction in environmental impact caused by replacing natural sand with expanded vermiculite as an aggregate in coating mortars. In this study, we analyzed the compressive strength and tensile bond strength of coating mortars produced from a 1:1:6 mix by volume and with 10, 20, 30, 40 and 50% replacement of natural aggregate with expanded vermiculite, comparing them with a reference mix. The experimental stage consisted of characterizing the aggregates, making the mortars and testing them in the fresh and hardened state. According to NBR 13281-1 (ABNT, 2023), the mixtures can be classified in terms of compressive strength as P3 (AN100, VE10, VE40 and VE50, with strengths between 2.5 and 4.5 MPa) and P4 (VE20 and VE30, with strengths between 4.0 and 6.5 MPa). Based on the same standard, the mixtures can be classified in terms of tensile bond strength as RA1 (AN100, VE40 and VE50, for strength greater than or equal to 0.2 MPa) and RA2 (VE10, VE20 and VE30, for strength greater than or equal to 0.3 MPa). It should be noted that the results for the intermediate traits VE20 and VE30, with compressive strengths between 4.0 and 6.5 MPa and tensile bond strengths greater than or equal to 0.3 MPa, can be classified as P4 and RA2 respectively. All the mixes complied with NBR 13749 (ABNT, 2013), which stipulates minimum values of 0.20 MPa for internal walls and 0.30 MPa for external walls. VE10, VE20 and VE30 were suitable for external cladding, while VE40 and VE50 were suitable for internal cladding. In these last two cases, the mixture stands out for meeting the standard and causing less environmental impact.
Российский сектор ИКТ: ключевые показатели январь – сентябрь 2024
Authors:   Национальный исследовательский университет «Высшая школа экономики», Абдрахманова Гульнара , Богданов Тарас ,   Национальный исследовательский университет «Высшая школа экономики», Демьянова Анна ,   Национальный исследовательский университет «Высшая школа экономики», Зинина Тамара ,   Национальный исследовательский университет «Высшая школа экономики», Ковалева Галина ,   Национальный исследовательский университет «Высшая школа экономики», Латушкина Ирина ,   Национальный исследовательский университет «Высшая школа экономики», Лола Инна ,   Национальный исследовательский университет «Высшая школа экономики», Рудник Павел ,   Национальный исследовательский университет «Высшая школа экономики», Рыжикова Зинаида ,   Национальный исследовательский университет «Высшая школа экономики»
Published: February 2025

Квартальный дайджест на основе официальной статистической информации
Mevsimsel ve yıllık zaman periyodunda yağış trend analizi, Ankara ili örneği
Authors: Çelik Mehmet Furkan , Pınarlık Murat , Selek Zeliha
Published: February 2025

Yağış, sıcaklık gibi iklim parametreleri üzerinde meydana gelen uzun süreli değişimlerin hidrolojik döngüde neden oldukları değişimler insan yaşamını olumsuz etkilemektedir. İklim değişikliğinin etkili olduğu ülkemizde su kaynaklarının en uygun şekilde kullanılması açısından hidrometeorolojik çalışmalar önem arz etmektedir. Bu çalışmada, Ankara ilinde yer alan 7 adet meteoroloji gözlem istasyonun yağış verileri mevsimsel ve yıllık olarak incelenerek trend analizleri yapılmıştır. Analizlerde Petitt Homojenlik Testi, Mann Kendall ve Yenilikçi Trend Analizleri kullanılmıştır. Homojenlik testine göre yıllık sonuçlarda sadece bir istasyonda kırılma meydana gelmiştir. Mevsimsel sonuçlarda ise sadece kış ve yaz mevsimlerinde birer istasyonda kırılma olduğu tespit edilmiştir. Mann Kendall trend analizlerinde hem yıllık hem de mevsimsel olarak sadece birer adet istasyonda trend belirlenmiştir. Yenilikçi Trend Analizi testi sonuçlarında daha belirgin sonuçlar elde edilmiştir. Yıllık olarak bir adet istasyonda azalan, beş adet istasyonda artan trend tespit edilmiştir. Mevsimsel olarak sonbaharda üç adet istasyonda azalan, dört adet istasyonda ise artan trend tespit edilmiştir. Üç yöntem kullanılarak elde edilen sonuçlar incelenmiş ve bölgenin mevcut yağış trendi değerlendirilmiştir.
Bakırın ısıl genleşme katsayısının moleküler dinamik simülasyonuyla araştırılması: Boyut ve kristal sayısının tek- ve çok-kristalli yapılar üzerindeki etkisi
Authors: Şen Sadri
Published: February 2025

Bakır, hem makro hem de nanoölçekte, sahip olduğu mekanik, elektronik, optik ve termal özelliklerin benzersiz kombinasyonu nedeniyle bilimsel ve teknolojik olarak araştırmacıların dikkatini çekmiştir. Nanoölçeklerde yapı-özellik ilişkilerinin anlaşılması, NEMS ve MEMS uygulamaları için önemlidir. Termal genleşme katsayısı (TGK) bu özelliklerden biridir. TGK için modeller tek-kristalli (TKY) ve çok-kristalli (ÇKY) olarak oluşturuldu. TKY ve ÇKY modeller, farklı boyutta 5 ana seri olarak oluşturuldu. Bunun yanında, ÇKY modellerinin her birinin farklı tane sayılı 5 farklı alt serisi bulunmaktadır. Böylece, TKY araştırmalar, faklı boyuttaki 5 model üzerinde yürütülürken, ÇKY hesaplamaları farklı boyut ve farklı tane sayılı olmak üzere 25 model üzerinde yapılmıştır. Bu çalışmalarda, TGK üzerinde; i-) TKY’de boyut değişiminin, ii-) belirli bir sabit boyuttaki ÇKY’de artan tane sayısının, iii-) farklı boyutlardaki ÇKY’de boyut artışına bağlı olarak tane sayısının etkileri incelenmiştir. Boyut ve tane sayısı değişiminin, TGK üzerindeki etkileri için hazırlanan ÇKY’lerde, farklı boyutlardaki ÇKY'lerin tane sayısı artışları, farklı boyutlardaki modellerin aynı alt serilerinde ortalama tane hacmi (OTH) aynı olacak şekilde ayarlanmıştır. Böylece, hem yapının boyutunun, hem tane sayısının ve hem de aynı ortalama tane hacminin farklı sıcaklıklarda TGK’ye etkisi derinlemesine incelenebilmiştir. Sonuçlar literatür ile iyi bir uyum göstermiştir. MDS ile yapılan hesaplamalarda, gömülü atom modelinin (GAM) potansiyel enerji fonksiyonu (PEF) kullanılmıştır.
Application of Karhunen-Loève Transform Algorithms in Hydrogeological Parameter Compression: A Comparative Study
Authors: Yue Chao , Wang Jianping , Wang Zitao
Published: February 2025

This paper proposes a parameter compression method using the Karhunen-Loève Transform (K-L) to reduce the computational burden of parameter inversion in groundwater models. Two spatial distributions of hydraulic conductivity (K) were generated using Kriging interpolation and Sequential Gaussian Simulation (SGS), and the K-L transform was applied to reduce their dimensionality. The method’s generality was assessed by varying model boundaries, extreme values of K, and simulation periods. The results showed that sequentially adding different boundary conditions resulted in high accuracy in model output. The model was most accurate when K values were within the range of 50-100 m/d, and its performance decreased as the range of K expanded. The model also exhibited high accuracy across various time periods within a single stress period. Dimensionality reduction through Kriging-KL and SGS- KL resulted in high accuracy of model-simulated heads, with R2 values exceeding 0.80 and 0.98 respectively. Overall, the K-L transform efficiently reduces parameter dimensions without compromising model performance. SGS-KL showed greater robustness under varying parameters, indicating its suitability for complex groundwater systems. This study contributes to efficient groundwater model inversion and provides valuable insights into the characteristics of groundwater systems.
The Crucial Role of Geothermal Fluids in Reducing the Water and Carbon Footprints of Lithium Mining in Salt Flats Worldwide
Authors: Alam Mohammad Ayaz
Published: February 2025

Thermal waters, which often have a high Li concentration, can influence the formation of Li-rich brines in the salt flats. Several studies suggest that geothermal activity accelerates the leaching of Li-rich volcanic rocks in the catchment areas of the closed basins, contributing to higher Li concentrations in brines. Considering that there is no salt flat in Chile or other parts of the world that does not have a present-day (active) or palaeo-geothermal system, there is a need for a holistic geoscientific study of the salt flats to investigate the association between lithium enrichment of brine in the salt flats and geothermal systems present in the host closed basins. The expected results of such studies in different salt flats will help understand the role of geothermal systems in forming economic Li deposits that could be selectively mined sustainably. This is because thermal waters can also concentrate Li in specific horizons, allowing for selective extraction with minimal impact on freshwater aquifers. This would be possible because conductive heating by underlying thermal water could induce circulation (convective overturn) of basin brines within hydrologically connected horizons. Accordingly, this geothermally induced brine circulation may develop a heterogeneous subsurface Li distribution, where thermal waters could be instrumental in forming Li-enriched horizons in subsurface brine. Deciphering and modeling the latter will form a strong and tangible basis for developing environmentfriendly methods for Li mining that will have negligible influence on the groundwater and wetland ecosystems using drilling technologies prevalent in the hydrocarbon industry for extracting particular sedimentary horizons. Further, geothermal systems present in the closed hydrologcal basins could aid in reducing the environmental footprint of Li mining by providing thermal energy for extraction processes and electricity generation using low-enthalpy binary power plants. Considering the focus on direct extraction of Li (DLE) in Chile and neighboring countries, it is necesary to integrate it with geothermal following holistic geoscientific studies involving geological, geochemical and geophysical investigations, validated by exploratory drilling. This will help mitigate environmental challenges associated with current DLE technologies by using geothermal water in the extraction process and expertise from the geothermal industry in brine recharge.
Costa Lab Nanoject Virus Injections-CU v1
Authors: Vicente Mafalda
Published: February 2025

This is the standard stereotaxic/Nanoject injection mouse surgery protocol for the Costa lab at Columbia University.
Immunofluorescence staining and image analysis v1
Authors: Jose Perez J. Maria
Published: February 2025

Immunofluorescence staining and image analysis
Extraction of microbial cells from methane-seep carbonate rocks for single-cell analyses (e.g. BONCAT-FISH) using “combination buffer” and percoll density centrifugation v1
Authors: J Mayr Magdalena , J. Orphan Victoria
Published: February 2025

Protocol to separate cells from carbonate rock to be able to image cells on a filter or slide with a microscope, using e.g. DAPI staining, BONCAT-FISH to see translationally active cells or for other subsequent single-cell techniques. In this protocol we use a combination buffer (Eichorst et al 2015) originally developed for soil and combine it with a percoll density centrifugation to separate the cells from rock material. The steps included in the protocol are: Cell fixation, cell extraction, density separation, preparing filter for DAPI staining or slides for BONCAT-FISH.
How Technology Can Change Educational Research? Definition, Factors for Improving Quality of Education and Computational Bibliometric Analysis
Authors: Al Husaeni Dwi Fitria , Al Husaeni Dwi Novia , Nandiyanto Asep Bayu Dani , Rokhman Mauhibur , Chalim Saefuddin , Chano Jiraporn , Al Obaidi Abdulkareem Sh. Mahdi , Roestamy Martin
Published: February 2025

This study explains all factors relating to the definition and current research trends in how technology can improve education. This study explains how strategies are developed to create and improve the quality of education, including communication, the input of technology (such as IT, ICT, AI, AR, etc.), curriculum and education level, and the relationship between social studies, humanities, science, and industry, as well as management and facilities. We demonstrated current technology using social media, for educators to implement it to improve the teaching and learning process. Bibliometric and theoretical analysis, based on the Google Scholar database from 2018-2023, was used. The search results found 988 articles with the keywords of "Education Technology" AND "Indonesia". Research on educational technology in Indonesia has increased every year. 113 terms were found based on network visualization, which was divided into 6 clusters. The “Indonesia” term appeared 596 times and the term “education technology” appeared 133 times. Co-authorship analysis found 2035 authors have contributed. Completing this research leads to the creation of future research, determining what next research subjects can appear, especially in the field of education.
Effects of Sustained Deficit Irrigation on Vegetative Growth and Yield of Plum Trees Under the Semi-Arid Conditions: Experiments and Review with Bibliometric Analysis
Authors: Laita Meriame , Sabbahi Rachid , Elbouzidi Amine , Hammouti Belkheir , Messaoudi Zerhoune , Benkirane Rachid , Aithaddou Houssain
Published: February 2025

This study evaluated sustained deficit irrigation on the production and quality of plum trees under the semi-arid conditions of the Saïs plain, with four water regimes: T0 (dose practiced by the farmer which may be equal to or greater than 100% ETc), T1 (100% ETc), T2 (80%ETc) and T3 (60%ETc) during the agricultural year 2017/2018. The results of the study showed a significant influence of the irrigation dose on vegetative parameters such as shoot diameter and length, physiological parameters such as leaf temperature, production parameters such as fruit yield per tree and fruit number per tree, and quality parameters such as acidity and sugar content. The fruits grown on T3 (60 %ETc)-treated trees had the highest sugar content. The total acidity of the fruit juice decreased with the increase in sugar content. In summary, the main parameters of vegetative growth, production, and quality were significantly affected by the reduction in irrigation dose. The findings also suggested that a 20% reduction in irrigation dose is feasible without significantly affecting the yield. A bibliometric analysis is conducted on the collected papers on Scopus on sustainable deficit irrigation and its impact on vegetative growth from 1999 to 2023.
Application of Particle Swarm Optimization in Duty Cycle Adjustment for Optimization of Oxyhydrogen Generator
Authors: Pertiwi Fungky Dyan , Anindito Dhimas Cahyo , Habibi Ilham , Kusumadewi Tri Vicca , Setiyo Muji , Kolakoti Aditya
Published: February 2025

The duty cycle of pulse width modulation is used to adjust the current of the oxyhydrogen generator with on-off square signals. These signals are essential for an oxyhydrogen gas generator to reduce thermal operation, improve the quality of oxyhydrogen gas, and enhance efficiency. A framework combining particle swarm optimization and regression analysis was proposed to determine the minimum temperature and production time of oxyhydrogen gas while maximizing efficiency using a single input, the duty cycle. The optimization results indicated that the duty cycle for the optimum solution remained within the upper and lower temperature boundaries. In this study, particle swarm optimization successfully provided valuable insights for practical applications in renewable energy technologies.
The Use of the Natuna Game About the Natural Wealth of the Natuna Marine on National Awareness of the Post-Millennial Generation
Authors: Ibrahim Intan Maharani , Suryadi Karim , Darmawan Cecep , Nurbayani Siti
Published: February 2025

This research aims to explain the influence of using Natuna games in understanding natural wealth on the national consciousness of the post-millennial generation (Gen-Z). The method used is Design-based Research, through the stages of analysis, design, development, and evaluation. The results of the research are in the form of Game Natuna. Several validation tests were carried out on the product, namely in terms of material, media, and readability for representatives of the Gen-Z with a validation percentage in terms of material, media, and readability respectively of 95.22, 90.25, and 92.60%. Apart from that, a media implementation was also carried out on 80 Gen-Z people, where the results showed there was a significant difference in national awareness of Gen-Z who used Natuna games compared to Gen-Z who did not use Natuna games. Where students who use the Natuna game have an average national awareness score of 84.10, while those who don't use the Natuna game have an average score of 81.60. It can be concluded that the game Natuna Media developed is very suitable for use and is expected to increase awareness across generations in maintaining national resilience. It is recommended for further research to develop the Natuna game more widely and increase the sense of national awareness.
How to Count Speed? Utilizing Android Applications to Support a Concept Attainment Model to Help Mathematical Thinking Skills
Authors: Abidin Zaenal , Herman Tatang , Wahyudin W. , Wiryanto W. , Farokhah Laely , Penehafo Amadhila Elina
Published: February 2025

Examining and explaining the mathematical thinking skills of primary school students who employed an Android app as a concept attainment technique was the aim of this study. The inquiry used a 3 x 2 factorial design and a quantitative methodology. The study included twenty-eight fifth-grade students from two different courses. The results showed that students' mathematical thinking skills differed between those taught using a conventional strategy and those taught using a concept attainment method using an Android app and digital comic. Different mathematical thinking abilities are shown by students with levels of self-efficacy, according to the other research. This is because, in comparison to students in other groups, students with high levels of self-efficacy have more prior knowledge. Ultimate result shows no relationship between developing mathematical thinking skills and self-efficacy. This study could help educate people about various educational programs and media that can be used to enhance their capacity for mathematical thinking.
Effect of Substrate and Water on Cultivation of Sumba Seaworm (Nyale) and Experimental Practicum Design for Improving Critical and Creative Thinking Skills of Prospective Science Teacher in Biology and Supporting Sustainable Development Goals (SDGs)
Authors: Kerans Geterudis , Sanjaya Yayan , Liliasari L. , Pamungkas Joko , Ate Yustinus Ghanggo
Published: February 2025

This research aims to determine the effect of substrate and water type on the cultivation of Sumba seaworm (Nyale) and develop an authentic inquiry project-based practicum instrument on Nyale as Polychaeta to improve critical and creative thinking skills of prospective science teachers. The results of experimental research showed that the substrate of sea sand and sea coral can be used in Nyale cultivation because it can provide a higher survival rate for this organism. Cultivation without substrate causes Nyale to survive less. Sea water is needed to be used in cultivation. The development of an authentic inquiry project practicum instrument about Nyale shows that the instrument is feasible to be used in practicum to improve the critical and creative thinking skills of prospective science teachers. This research contributes well to the development of authentic science learning that can create meaningful science learning for students. This research also supports a problem solver for current issues in the sustainable development goals (SDGs).
GeoSmart Application as a Tool for Interactive Learning: Literature Review Completed with Experiments for Improving Understanding of Geospheric Phenomena in Geography Education
Authors: Fadjarajani Siti , As’ari Ruli , Ningrum Epon , Ahmad Mohammad Zohir
Published: February 2025

This study creates and tests the GeoSmart app as an interactive learning tool for high school students to understand geospheric phenomena. The research encompassed concept creation, design, material acquisition, assembly, testing, and dissemination. The study involved a planned group of high school students from Tasikmalaya City. We administered questionnaires and comprehension tests both before and after using the app to collect data. The program significantly improved students' understanding of geospheric phenomena. Statistics verified these benefits, showing that GeoSmart's interactive features engage students and help them understand complicated subjects. The findings suggest that the GeoSmart application has considerable potential for broader adoption in geography education, as it effectively enhances both learning quality and student motivation. This study stresses how important technology is in education and suggests more research be done to look into the long-term effects and wider use of GeoSmart apps.
Digital Applications as Assistive Technology for Students with Disabilities
Authors: Restianty Ajani , Sumartias Suwandi , Hadisiwi Purwanti , Hafiar Hanny
Published: February 2025

This research aims to develop and design the application of assistive technology to transform the lives of individuals with disabilities, providing them with the skills and tools they need to overcome barriers that previously prevented them from fully participating in society. This research focuses on developing digital applications as a technological support for media lecturers to use in learning for students with disabilities. The research method used in this research is Design Based Research, which consists of three main stages, namely needs assessment, design process, technology used, and making interactive prototypes. Current developments in assistive technology and disability research indicate a growing interest in using assistive technology to promote inclusive practices in the pursuit of knowledge. There is a focus on creating diverse and culturally adaptive learning environments that suit diverse needs and experiences and increasing awareness of society's challenges and prejudices when using assistive technology. Adopting digital apps as assistive technology is not only a huge step toward making educational settings more inclusive and accessible for students with disabilities but also provides a variety of capabilities to meet the different requirements of students, such as configurable displays, interactive and multisensory learning possibilities, and interaction with other assistive technology.
An Application of Statistical Testing: A Guide to Basic Parametric Statistics in Educational Research Using SPSS
Authors: Rahayu Nur Indri , Muktiarni M. , Hidayat Yusuf
Published: February 2025

Statistics is usually associated with a series of numbers, so it is often interpreted as a numerical description. However, statistics in the context of science is not just a series of numbers; statistics is more than just a collection of raw data. Statistics are also used to analyze data, such as graphs, displaying data in tabular form, forecasting, conducting various hypothesis tests, and other uses. The primary purpose of this study is to examine the application of various descriptive and inferential statistical tests in educational research so that it can teach how to collect data, present it in an easy-to-understand form, analyze data, interpret data, and draw conclusions. The data used in this study are secondary data sourced from research, websites, books, and various journals. The research method used is to use a literature review. Based on multiple literature reviews, it was found that the use of appropriate statistical techniques is an essential requirement for the implementation of effective social and behavioral research. In addition, the study concluded that choosing the proper statistical test is necessary for making excellent and specific conclusions. Thus, statistical analysis is essential in making educational research effective, efficient, and flourishing by the objectives set.
Advancing Language Education in Indonesia: Integrating Technology and Innovations
Authors: Luckyardi Senny , Munawaroh Silvi , Abduh Amirullah , Rosmaladewi R. , Hufad Achmad , Haristiani Nuria
Published: February 2025

Language learning in Indonesia's educational environment is accelerating change due to the introduction of novel technologies and teaching methods. This paper analyzed the essential functions of digital tools, the internet, and contemporary educational approaches to enhancing Indonesian language learning results. When considering the challenges of low penetration in remote areas and fluctuating technological maturity, opportunities exist to explore the potential of technology to bridge the language acquisition gap. Drawing on a review of several projects (i.e., mobile applications, e-learning platforms, and artificial intelligence (AI)-driven language support), the current study outlines their success in fostering multilingualism, enhancing engagement rates, and developing mother tongue and second language skills. The outcome suggests that education through language for Indonesian learners will be successful if there is a balance between traditional teaching advantages, such as face-to-face teaching, and modern technology's power and freedom. Policies, pedagogical, and institutional ideas are proposed to build a sustainable, inclusive, and dynamic model for a language education framework based on the sake of its citizenry.