bluuebunny/crossref_metadata_2025 huggingface dataset:
Interaction between Oxytocin Genotypes and Early Experience Predicts Quality of Mothering and Postpartum Mood
Authors: Atkinson Leslie , Mileva-Seitz Viara , Steiner Meir , Meaney Michael  J. , Levitan Robert , Kennedy James  L. , Sokolowski Marla  B. , Fleming Alison  S.
Published: July 2021

Individual differences in maternal behavior are affected by both early life experiences and oxytocin, but little is known about genetic variation in oxytocin genes and its effects on mothering. We examined two polymorphisms in the oxytocin peptide gene OXT (rs2740210 and rs4813627) and one polymorphism in the oxytocin receptor gene OXTR (rs237885) in 187 Caucasian mothers at six months postpartum. For OXT, both rs2740210 and rs4813627 significantly associated with maternal vocalizing to the infant. These polymorphisms also interacted with the quality of care mothers experienced in early life, to predict variation in maternal instrumental care and postpartum depression. However, postpartum depression did not mediate the gene-environment effects of the OXT SNPs on instrumental care. In contrast, the OXTR SNP rs237885 did not associate with maternal behavior, but it did associate with pre-natal (but not post-natal) depression score. The findings illustrate the importance of variation in oxytocin genes, both alone and in interaction with early environment, as predictors of individual differences in human mothering. Furthermore, depression does not appear to have a causal role on the variation we report in instrumental care. This suggests that variation in instrumental care varies in association with a gene-early environment effect regardless of current depressive symptomatology. Finally, our findings highlight the importance of examining multiple dimensions of human maternal behavior in studies of genetic associations.
Theistic Replies to the A Priori Argument for Atheism
Authors: Kraay Klaas
Published: July 2021

In the central chapter of Can God Be Free?, William Rowe offers what amounts to an a priori argument for atheism. In what follows, I first clarify this argument, and I then defend it against recent criticisms due to William Hasker. Next, however, I outline four ways in which theists might plausibly reply to Rowe's argument.
A mega-index for the Americas and its underlying sustainable development correlations
Authors: Shaker Richard Ross
Published: July 2021

Indicators and their composite indices have been embraced as development tools for guiding humanity toward a sustainable destination. In response, public and private organizations have generated hundreds of these metrics, making their application overwhelming to policymakers, planners, and scientists. Past reviews have revealed that a majority of common development indices have theoretical or quantitative shortcomings, supporting that there is no consensus regarding their theoretical basis, design, use, thresholds-of-effect, or validation. In response, this study was designed around four guiding research questions: (i) What are the underlying development themes within a collection of established sustainability indices, and what distinguishes winning locations from losing ones? (ii) Are the three major divisions of sustainability (economic growth, social equity, environmental integrity) equally represented by current sustainable development measuring initiatives? (iii) Could just a few common and freely available indicators capture all present dimensions of sustainable development? (iv) Would a new sustainable development mega-index research paradigm improve humanity’s ability to assess progress toward sustainability? Those questions were investigated using data from 30 mostly contiguous Western Hemisphere nations and three amassing methodological objectives. First, 31
known indices were reduced into underlying dimensions (factors) of sustainable development. Next, those factors were combined (aggregated) into the first mega-index of sustainable development (MISD). Finally, 11 common development indicators were explored regarding collinearity and explanatory power of the sustainable development dimensions and MISD. Seven latent dimensions (sub-metrics) captured over 85% of the variation of the original 31 indices, with socioeconomic themes dwarfing environmental ones. The factors conveyed: (F1) socioeconomic well-being synergies; (F2) economic freedom and democracy; (F3) environmentally efficient happiness; (F4) ecosystem wellbeing; (F5) peace to economic vulnerability tradeoff; (F6) natural resources protection; and (F7) environmental stewardship and risk resilience. MISD is the geometric mean of the seven sub-metrics,which were directed toward sustainability, and rescaled (normalized) 0 (worst case) to 100 (best case).
Geographically, this study ranked Belize best overall, followed by Guyana, Panama, Uruguay, and Canada; Barbados ranked worst, preceded by Haiti, Trinidad and Tobago, Mexico, and Cuba. Winning countries were characterized by low population density, increased forestland, decreased urban, and larger country area. Child mortality and population growth rate remained negative predictors of socioeconomic conditions; however per-capita CO2 sacrificed ecological integrity for improved human well-being. Mega-index creation will serve as an important scientific stepping-stone for improving
accuracy and simplifying valuations of sustainable development, thus others should follow.
Induced Heating In Steel-Beam Reinforced Ceilings Over Three-Phase Transformer Delta Closures
Authors: Ryff Peter F
Published: July 2021

Due to eddy currents, high temperatures often occur in structural parts adjacent to conductors carrying large currents. This paper deals with this problem and specifically with the minimum safe height and orientation of steel beams in a reinforced concrete ceiling above a three-phase transformer delta closure.
Special issue: African Canadians, gender, and sexuality
Authors: Jean-Pierre Johanne , Mccready Lance
Published: July 2021

This is the introduction to a special issue, focusing on African Canadians, gender and sexuality. This special issue adds to the body of empirical knowledge about gender and sexuality and how they relate to identities, structures, and systems within African Canadian communities. All of the articles feature qualitative inquiries. These were conducted in Nova Scotia, Quebec, Ontario, and British Columbia and focused on education, policing, sexual agency and romantic relationships.

Keywords: Black; African Canadians; Race; Gender; Sexuality; Intersectionality
Special issue: African Canadians, gender,and sexuality
Authors: Jean-Pierre Johanne , Mccready Lance
Published: July 2021

This is the introduction to a special issue, focusing on African Canadians, gender and sexuality. This special issue adds to the body of empirical knowledge about gender and sexuality and how they relate to identities, structures, and systems within African Canadian communities. All of the articles feature qualitative inquiries. These were conducted in Nova Scotia, Quebec, Ontario, and British Columbia and focused on education, policing, sexual agency and romantic relationships.
Keywords: Black; African Canadians; Race; Gender; Sexuality; Intersectionality
Immigrant Mental Health, A Public Health Issue: Looking Back and Moving Forward
Authors: George Usha , Thomson Mary S. , Chaze Ferzana , Guruge Sepali
Published: July 2021

The Mental Health Commission of Canada’s (MHCC) strategy calls for promoting the health and wellbeing of all Canadians and to improve mental health outcomes. Each year, one in every five Canadians experiences one or more mental health problems, creating a significant cost to the health system. Mental health is pivotal to holistic health and wellbeing. This paper presents the key findings of a comprehensive literature review of Canadian research on the relationship between settlement experiences and the mental health and well-being of immigrants and refugees. A scoping review was conducted following a framework provided by Arskey and O’Malley (Int J Soc Res Methodol 8:19–32, 2005). Over two decades of relevant literature on immigrants’ health in Canada was searched. These included English language peer-reviewed publications from relevant online databases Medline, Embase, PsycInfo, Healthstar, ERIC and CINAHL between 1990 and 2015. The findings revealed three important ways in which settlement affects the mental health of immigrants and refugees: through acculturation related stressors, economic uncertainty and ethnic discrimination. The recommendations for public health practice and policy are discussed.
Interpersonal Engagement Mediates the Relation between Maternal Affect and Externalising Behaviour in Young Children with Type 1 Diabetes
Authors: Atkinson Leslie , Gonzalez Andrea , Chisholm Vivienne
Published: July 2021

Mother-child interactions around a shared activity have been shown to play a key role in the development of young children’s capacity to interact cooperatively with others. This evidence is particularly germane to type 1 diabetes (T1D) management in younger children where cooperation with parental treatment efforts is crucial for treatment success and where maternal distress and child behavioural problems are risk factors for treatment management, biomedical and psychological outcomes. In 49 4-to-8 year old children with T1D, we investigated whether the association between maternal affect and child problematic behaviour is mediated by mother-child interactions in the context of a T1D-relevant collaborative problem-solving activity. Mothers completed standardised measures of maternal and child psychological adjustment and interacted with their children in the problem-solving activity, analysed for quality of interpersonal engagement based on evaluations of maternal (sensitivity and cognitive stimulation) and dyadic (joint attention and warmth) behaviours. Mediation analyses confirmed the hypothesis that interpersonal engagement mediates the relation between maternal affective state and child behavioural problems. Specifically, more negative maternal affect is associated with lower levels of interpersonal engagement; these less engaged interactions in turn are associated with more behavioural problems in children. These findings are consistent with research involving typically developing children. The implications of our findings are twofold. First, in the context of psychological adjustment to T1D, maternal affect and mother-child interactions are 2 potential targets for interventions which promote cooperative interactions. Second, understanding and caring for children at biological risk requires attention to developmental psychology theory and method; in particular, research addressing parent-child cooperation carries both conceptual and clinical relevance.
The impact of facilities and service-based competition on Internet services provision in the Canadian Broadband Market
Authors: van Gorp Annemijn , Middleton Catherine A.
Published: July 2021

A variety of studies have focused on the effect of competition in broadband markets on increasing broadband penetration rates. Few studies however have focused on the extent to which competition also results in innovation in the marketplace, as demonstrated by increased broadband speeds, and other improvements that provide value to broadband users. This paper considers the effectiveness of market competition as a means of encouraging broadband providers to offer innovative services that meet citizens’ increasing needs for affordable high quality and high speed broadband connectivity. The study focuses on the provision of broadband services in Canada, a country where consumers were early adopters of broadband and where the policy environment has encouraged competition in the broadband market from its inception. Drawing on data from the OECD and the Canadian Radio-television and Telecommunications Commission (CRTC), the paper demonstrates that Canada’s regulatory regime does not appear to
be sufficient to enable a competitive marketplace that results in the provision of innovative broadband services.
On or off the Slate: University Library E-Reserve Supports Web-Based Learning
Authors: Cheung Ophelia
Published: July 2021

Ryerson University Library in Toronto, Canada, embarked on an E-Reserve pilot project in 2004, providing electronic links to journal articles and scanned documents for course readings. Insufficient time allowed by faculty for copyright clearance, excessive copyright cost and the difficulty of achieving a single sign-on by users to access e-Reserve in Blackboard, the University’s courseware, were the major issues. Despite setbacks, E-Reserve continued to undertake innovative projects, using the new E-Reserve module in Blackboard to integrate course readings with faculty course pages, utilizing SFX open linking to connect citations to full-text articles, and experimenting with Web streaming of videos in Blackboard.
The role of the library in the first college year: the Canadian perspective
Authors: Trescases Ursula
Published: July 2021

The role of the library in the first college year: the Canadian perspective
Investigating Forest Disturbance Using Landsat Data in the Nagagamisis Central Plateau, Ontario, Canada
Authors: Forsythe K. Wayne , McCartney Grant
Published: July 2021

The Nagagamisis Central Plateau (located in Northern Ontario, Canada) is an area of distinct natural and cultural significance. The importance of this land was officially recognized in 1957 through the establishment of the Nagagamisis Provincial Park Reserve. The park has experienced significant expansion since its inception and is currently under development as one of Ontario Parks ‘Signature Sites’. Since the 1980s, timber harvest activity has led to widespread forest disturbance just outside of the park boundaries. This research is focused on the detection of stand level forest disturbances associated with timber harvest occurring near Nagagamisis Provincial Park. The image time-series data selected for this project were Landsat TM and ETM+; spanning a twenty-five year period from 1984 to 2009. The Tasselled Cap Transformation and Normalized Difference Moisture Index were derived for use in unsupervised image classification to determine the land cover for each image in the time-series. Image band differencing and raster arithmetic were performed to create maps illustrating the size and spatial distribution of stand level forest disturbances between image dates. A total area of 1649 km2 or 26.1% of the study area experienced stand level disturbance during the analysis period.
Exploring Multicriteria Decision Strategies in GIS with Linguistic Quantifiers – A Case Study of Residential Quality Evaluation
Authors: Malczewski Jacek , Rinner Claus
Published: July 2021

Commonly used GIS combination operators such as Boolean conjunction/disjunction and weighted linear combination can be generalized to the ordered weighted averaging (OWA) family of operators. This multicriteria evaluation method allows decision-makers to define a decision strategy on a continuum between pessimistic and optimistic strategies. Recently, OWA has been introduced to GIS-based decision support systems. We propose to extend a previous implementation of OWA with linguistic quantifiers to simplify the definition of decision strategies and to facilitate an exploratory analysis of multiple criteria. The linguistic quantifier-guided OWA procedure is illustrated using a dataset for evaluating residential quality of neighborhoods in London, Ontario.

This is a post-peer-review, pre-copyedit version of an article published in Journal of Geographical Systems. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10109-005-0159-2
Long-Chain Omega-3 Polyunsaturated Fatty Acids Have Developmental Effects on the Crop Pest, the Cabbage White Butterfly Pieris rapae
Authors: Hixson Stefanie M. , Shukla Kruti , Campbell Lesley , Hallett Rebecca H. , Smith Sandy M. , Packer Laurence , Arts Michael Theodore
Published: July 2021

Nutritional enhancement of crops using genetic engineering can potentially affect herbivorous pests. Recently, oilseed crops have been genetically engineered to produce the long-chain omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) at levels similar to that found in fish oil; to provide a more sustainable source of these compounds than is currently available from wild fish capture. We examined some of the growth and development impacts of adding EPA and DHA to an artificial diet of Pieris rapae, a common pest of Brassicaceae plants. We replaced 1% canola oil with EPA: DHA (11:7 ratio) in larval diets, and examined morphological traits and growth of larvae and ensuing adults across 5 dietary treatments. Diets containing increasing amounts of EPA and DHA did not affect developmental phenology, larval or pupal weight, food consumption, nor larval mortality. However, the addition of EPA and DHA in larval diets resulted in progressively heavier adults (F 4, 108 = 6.78; p = 0.011), with smaller wings (p < 0.05) and a higher frequency of wing deformities (R = 0.988; p = 0.001). We conclude that the presence of EPA and DHA in diets of larval P. rapae may alter adult mass and wing morphology; therefore, further research on the environmental impacts of EPA and DHA production on terrestrial biota is advisable.
Precise Point Positioning Using Triple GNSS Constellations in Various Modes
Authors: Afifi Akram , El-Rabbany Ahmed
Published: July 2021

This paper introduces a new dual-frequency precise point positioning (PPP) model, which combines the observations from three different global navigation satellite system (GNSS) constellations, namely GPS, Galileo, and BeiDou. Combining measurements from different GNSS systems introduces additional biases, including inter-system bias and hardware delays, which require rigorous modelling. Our model is based on the un-differenced and between-satellite single-difference (BSSD) linear combinations. BSSD linear combination cancels out some receiver-related biases, including receiver clock error and non-zero initial phase bias of the receiver oscillator. Forming the BSSD linear combination requires a reference satellite, which can be selected from any of the GPS, Galileo, and BeiDou systems. In this paper three BSSD scenarios are tested; each considers a reference satellite from a different GNSS constellation. Natural Resources Canada’s GPSPace PPP software is modified to enable a combined GPS, Galileo, and BeiDou PPP solution and to handle the newly introduced biases. A total of four data sets collected at four different IGS stations are processed to verify the developed PPP model. Precise satellite orbit and clock products from the International GNSS Service Multi-GNSS Experiment (IGS-MGEX) network are used to correct the GPS, Galileo, and BeiDou measurements in the post-processing PPP mode. A real-time PPP solution is also obtained, which is referred to as RT-PPP in the sequel, through the use of the IGS real-time service (RTS) for satellite orbit and clock corrections. However, only GPS and Galileo observations are used for the RT-PPP solution, as the RTS-IGS satellite products are not presently available for BeiDou system. All post-processed and real-time PPP solutions are compared with the traditional un-differenced GPS-only counterparts. It is shown that combining the GPS, Galileo, and BeiDou observations in the post-processing mode improves the PPP convergence time by 25% compared with the GPS-only counterpart, regardless of the linear combination used. The use of BSSD linear combination improves the precision of the estimated positioning parameters by about 25% in comparison with the GPS-only PPP solution. Additionally, the solution convergence time is reduced to 10 minutes for the BSSD model, which represents about 50% reduction, in comparison with the GPS-only PPP solution. The GNSS RT-PPP solution, on the other hand, shows a similar convergence time and precision to the GPS-only counterpart.
Map-Based Exploratory Evaluation of Non-Medical Determinants of Population Health
Authors: Rinner Claus , Taranu John P.
Published: July 2021

Multi‐criteria evaluation (MCE) and decision‐making are increasingly combined with interactive tools to assist users with visual thinking and exploring decision strategies. The interactive control of criterion combination rules and the simultaneous observation of geographic space and criterion space provide a means of investigating the sensitivity of the decision outcome to the decision‐maker's preferences. The Analytic Hierarchy Process (AHP) is an MCE method that has been successfully implemented in management processes including those addressed by Geographic Information Systems. In this paper, we present a map‐based, interactive AHP implementation, which provides a link between a well‐understood decision support method and exploratory geographic visualization. Using a case study with public health data for the Province of Ontario, Canada, we demonstrate that exploratory map use increases the effectiveness of the AHP‐based evaluation of population health.
Transnationalizing Families: Canadian Immigration Policy and the Spatial Fragmentation of Care-giving among Latin American Newcomers
Authors: Bernhard Judith K. , Landolt Patricia , Goldring Luin
Published: July 2021

Complex factors associated with migration and immigration policies contribute to the dispersion of families across space. We draw on interviews with 40 Latin American women in Toronto who experienced separation from children as a result of migration and argue that Canadian immigration policy and elements of the women’s context of departure lead to the systemic production of transnational family arrangements. Once in Canada, the women dealt with unexpected lengths of separation, the spatial dispersal of social reproduction, and post-reunification problems. The absence of a normative framework that could help the mothers make sense of family dispersal meant that their experiences of migration, family separation, reunification and settlement were marked by tension, guilt, isolation and shame.
Wireless Sensor Network Optimization: Multi-Objective Paradigm
Authors: Iqbal Muhammad , Naeem Muhammad , Anpalagan Alagan , Ahmed Ashfaq , Azam Muhammad
Published: July 2021

Optimization problems relating to wireless sensor network planning, design, deployment and operation often give rise to multi-objective optimization formulations where multiple desirable objectives compete with each other and the decision maker has to select one of the tradeoff solutions. These multiple objectives may or may not conflict with each other. Keeping in view the nature of the application, the sensing scenario and input/output of the problem, the type of optimization problem changes. To address different nature of optimization problems relating to wireless sensor network design, deployment, operation, planning and placement, there exist a plethora of optimization solution types. We review and analyze different desirable objectives to show whether they conflict with each other, support each other or they are design dependent. We also present a generic multi-objective optimization problem relating to wireless sensor network which consists of input variables, required output, objectives and constraints. A list of constraints is also presented to give an overview of different constraints which are considered while formulating the optimization problems in wireless sensor networks. Keeping in view the multi facet coverage of this article relating to multi-objective optimization, this will open up new avenues of research in the area of multi-objective optimization relating to wireless sensor networks.
Airfoil Performance at Low Reynolds Numbers in the Presence of Periodic Disturbances
Authors: Yarusevych S. , Kawall J. G. , Sullivan P. E.
Published: July 2021

The boundary-layer separation and wake structure of a NACA 0025 airfoil and the effect of external excitations in presence of structural vibrations on airfoil performance were studied experimentally. Wind tunnel experiments were carried out for three Reynolds numbers and three angles of attack, involving hot-wire measurements and complementary surface flow visualization. The results establish that external acoustic excitation at a particular frequency and appropriate amplitude suppresses or reduces the separation region and decreases the airfoil wake, i.e., produces an increase of the lift and∕or decrease of the drag. The acoustic excitation also alters characteristics of the vortical structures in the wake, decreasing the vortex length scale and coherency. Optimum excitation frequencies were found to correlate with the fundamental frequencies of the naturally amplified disturbances in the separated shear layer. The results suggest that acoustic waves play a dominant role in exciting the separated shear layer of the airfoil. Moreover, low-frequency structural vibrations are found to have a significant effect on airfoil performance, as they enhance the sound pressure levels within the test section.
Effects of Pitch-Based Short Carbon Fibers on the Workability, Unit Weight, and Air Content of Mortar Composite.
Authors: Safiuddin Md. , Abdel-Sayed George , Hearn Nataliya
Published: July 2021

Pitch is a viscoelastic polymer material consisting of aromatic hydrocarbons. It is used to produce carbon fibers with sheet-like crystal structures. The aim of the work presented in this paper was to evaluate the effects of pitch-based short carbon fibers on the workability, unit weight, and air content of freshly mixed mortar composite. Experimental investigation was carried out on five different types of mortar composite, including a control mortar. Four mortar composites were prepared including pitch-based short carbon fibers with 1–4% volume contents. The fresh mortar composites were tested to determine their slump, inverted slump cone flow (flow time, mass flow, and volume flow), unit weight, and air content. In addition, the correlation between the slump and flow time of various mortar composites was determined. It was found that the slump decreased with the increasing volume content of carbon fibers. The flow time of mortar composite increased, and therefore its mass flow and volume flow decreased with a greater volume content of carbon fibers. The slump was strongly correlated with the flow time, with a correlation coefficient of 0.9782. Furthermore, the unit weight of the fresh mortar composite decreased due to the incorporation of carbon fibers. However, amongst the different carbon fiber reinforced mortar composites, the mortar with 3% fiber volume content provided the highest unit weight. The air content results were consistent with the unit weight results. The change in air content of various mortar composites followed a trend reciprocal to that of unit weights. When the overall effects of carbon fibers were compared, it was observed that the fiber volume content higher than 3% resulted in a significantly low workability and provided a much lower unit weight with greater entrapped air content.
Synthesis of three-dimensional calcium carbonate nanofibrous structure from eggshell using femtosecond laser ablation
Authors: Tavangar Amirhossein , Tan Bo , Venkatakrishnan Krishnan
Published: July 2021

Background
Natural biomaterials from bone-like minerals derived from avian eggshells have been considered as promising bone substitutes owing to their biodegradability, abundance, and lower price in comparison with synthetic biomaterials. However, cell adhesion to bulk biomaterials is poor and surface modifications are required to improve biomaterial-cell interaction. Three-dimensional (3D) nanostructures are preferred to act as growth support platforms for bone and stem cells. Although there have been several studies on generating nanoparticles from eggshells, no research has been reported on synthesizing 3D nanofibrous structures.

Results
In this study, we propose a novel technique to synthesize 3D calcium carbonate interwoven nanofibrous platforms from eggshells using high repetition femtosecond laser irradiation. The eggshell waste is value engineered to calcium carbonate nanofibrous layer in a single step under ambient conditions. Our striking results demonstrate that by controlling the laser pulse repetition, nanostructures with different nanofiber density can be achieved. This approach presents an important step towards synthesizing 3D interwoven nanofibrous platforms from natural biomaterials.

Conclusion
The synthesized 3D nanofibrous structures can promote biomaterial interfacial properties to improve cell-platform surface interaction and develop new functional biomaterials for a variety of biomedical applications.
Assessing the effects of hybridization and precipitation on invasive weed demography using strength of selection on vital rates
Authors: Teitel Zachary , Klimowski Agnieszka , Campbell Lesley G.
Published: July 2021

Background
As global climate change transforms average temperature and rainfall, species distributions may meet, increasing the potential for hybridization and altering individual fitness and population growth. Altered rainfall specifically may shift the strength and direction of selection, also manipulating population trajectories. Here, we investigated the role of interspecific hybridization and selection imposed by rainfall on the evolution of weedy life-history in non-hybrid (Raphanus raphanistrum) and hybrid (R. raphanistrum x R. sativus) populations using a life table response experiment.
Active Collection of Land Cover Sample Data from Geo-Tagged Web Texts
Authors: Hou Dongyang , Chen Jun , Wu Hao , Li Songnian , Chen Feifei , Zhang Weiwei Zhang
Published: July 2021

Sample data plays an important role in land cover (LC) map validation. Traditionally, they are collected through field survey or image interpretation, either of which is costly, labor-intensive and time-consuming. In recent years, massive geo-tagged texts are emerging on the web and they contain valuable information for LC map validation. However, this kind of special textual data has seldom been analyzed and used for supporting LC map validation. This paper examines the potential of geo-tagged web texts as a new cost-free sample data source to assist LC map validation and proposes an active data collection approach. The proposed approach uses a customized deep web crawler to search for geo-tagged web texts based on land cover-related keywords and string-based rules matching. A data transformation based on buffer analysis is then performed to convert the collected web texts into LC sample data. Using three provinces and three municipalities directly under the Central Government in China as study areas, geo-tagged web texts were collected to validate artificial surface class of China’s 30-meter global land cover datasets (GlobeLand30-2010). A total of 6283 geo-tagged web texts were collected at a speed of 0.58 texts per second. The collected texts about built-up areas were transformed into sample data. User’s accuracy of 82.2% was achieved, which is close to that derived from formal expert validation. The preliminary results show that geo-tagged web texts are valuable ancillary data for LC map validation and the proposed approach can improve the efficiency of sample data collection.
Microstructure and mechanical properties of an ultrasonic spot welded aluminum alloy: the effect of welding energy
Authors: Peng He , Chen Daolun , Jiang Xianquan
Published: July 2021

The aim of this study is to evaluate the microstructures, tensile lap shear strength, and fatigue resistance of 6022-T43 aluminum alloy joints welded via a solid-state welding technique–ultrasonic spot welding (USW)–at different energy levels. An ultra-fine necklace-like equiaxed grain structure is observed along the weld line due to the occurrence of dynamic crystallization, with smaller grain sizes at lower levels of welding energy. The tensile lap shear strength, failure energy, and critical stress intensity of the welded joints first increase, reach their maximum values, and then decrease with increasing welding energy. The tensile lap shear failure mode changes from interfacial fracture at lower energy levels, to nugget pull-out at intermediate optimal energy levels, and to transverse through-thickness (TTT) crack growth at higher energy levels. The fatigue life is longer for the joints welded at an energy of 1400 J than 2000 J at higher cyclic loading levels. The fatigue failure mode changes from nugget pull-out to TTT crack growth with decreasing cyclic loading for the joints welded at 1400 J, while TTT crack growth mode remains at all cyclic loading levels for the joints welded at 2000 J. Fatigue crack basically initiates from the nugget edge, and propagates with “river-flow” patterns and characteristic fatigue striations.

Keywords: aluminum alloy; ultrasonic spot welding; EBSD; microstructure; tensile strength; fatigue
Sun Safety at Work Canada: a multiple case-study protocol to develop sun safety and heat protection programs and policies for outdoor workers
Authors: Kramer Desre M. , Tenkate Thomas , Strahlendorf Peter , Kushner Rivka , Gardner Audrey , Holness D. Linn
Published: July 2021

CAREX Canada has identified solar ultraviolet radiation (UV) as the second most prominent carcinogenic exposure in Canada, and over 75 % of Canadian outdoor workers fall within the highest exposure category. Heat stress also presents an important public health issue, particularly for outdoor workers. The most serious form of heat stress is heat stroke, which can cause irreversible damage to the heart, lungs, kidneys, and liver. Although the need for sun and heat protection has been identified, there is no Canada-wide heat and sun safety program for outdoor workers. Further, no prevention programs have addressed both skin cancer prevention and heat stress in an integrated approach. The aim of this partnered study is to evaluate whether a multi-implementation, multi-evaluation approach can help develop sustainable workplace-specific programs, policies, and procedures to increase the use of UV safety and heat protection.
A multidisciplinary collaborative web site for cardiovascular surgery
Authors: Fredericks Suzanne
Published: July 2021

Key Points:

* Patients, healthcare providers, and students have differing information needs in regard to surgical procedures.
* Often, separate information sources are designed for each group, resulting in fragmented information.
* Interactive, multidisciplinary, collaborative Web site is being developed to address the needs of all members of the healthcare team.

Cardiovascular surgical (CVS) settings encompass shared physical spaces that are accessible to patients, physicians, nurses, residents, and other members of the healthcare team.1 Dynamic, fluid interactions are constantly occurring among various members of the team at any point in time.1 Within these interactions, each member seeks to meet unique information and communication needs. For example, patients require information and support for learning and application of new self-care behavior skills, residents and students require mentorship to guide practice, and nurses and physicians require up-to-date empirical and theoretical information to revise and evaluate existing care endeavors. Traditionally, separate resources have been designed and administered for each member of the healthcare team; however, a single intervention that addresses the needs of each member of a multidisciplinary team has not been designed or evaluated.2,3 We developed an interactive, multidisciplinary, collaborative Web site as an intervention designed to address the needs of all members of the healthcare team, including patients. The Web site addresses the needs of postoperative patients, cardiovascular medical residents, nursing students, and other trainees, as well as nurses and physicians. In doing so, the site mimics the collective functioning of the existing healthcare teams within a shared physical space. The Web site can be accessed by different members of the healthcare team anywhere there is a wireless connection, and so it does not depend on shared physical space. Furthermore, it allows for interactive discussion through online chat rooms and open forums. As a result of this Web site, we anticipate an increase in the quality of patient care that is delivered within the CVS setting.
Shrinking microbubbles with microfluidics: mathematical modelling to control microbubble sizes
Authors: Salari A. , Gnyawali V. , Griffiths I. M. , Karshafian Raffi , Kolios Michael , Tsai Scott
Published: July 2021

Microbubbles have applications in industry and life-sciences. In medicine, small encapsulated bubbles (< 10 μm) are
desirable because of their utility in drug/oxygen delivery, sonoporation, and ultrasound diagnostics. While there are various techniques for generating microbubbles, microfluidic methods are distinguished due to their precise control and ease-offabrication. Nevertheless, sub-10 μm diameter bubble generation using microfluidics remains challenging, and typically requires expensive equipment and cumbersome setups. Recently, our group reported a microfluidic platform that shrinks microbubbles to sub-10 μm diameters. The microfluidic platform utilizes a simple microbubble-generating flow-focusing geometry, integrated with a vacuum shrinkage system, to achieve microbubble sizes that are desirable in medicine, and pave the way to eventual clinical uptake of microfluidically generated microbubbles. A theoretical framework is now needed to relate the size of the microbubbles produced and the system’s input parameters. In this manuscript, we characterize microbubbles made with various lipid concentrations flowing in solutions that have different interfacial tensions, and monitor the changes in bubble size along the microfluidic channel under various vacuum pressures. We use the physics governing the shrinkage mechanism to develop a mathematical model that predicts the resulting bubble sizes and elucidates the dominant parameters controlling bubble sizes. The model shows a good agreement with the experimental data, predicting the resulting microbubble sizes under different experimental input conditions. We anticipate that the model will find utility in enabling users of the microfluidic platform to engineer bubbles of specific sizes.
Widespread acquisition of antimicrobial resistance among Campylobacter isolates from UK retail poultry and evidence for clonal expansion of resistant lineages
Authors: Wimalarathna Helen M. L. , Richardson Judith F. , Lawson Andy J. , Elson Richard , Meldrum Richard , Little Christine L. , Maiden Martin C. J. , McCarthy Noel D. , Sheppard Samuel K.
Published: July 2021

Background
Antimicrobial resistance is increasing among clinical Campylobacter cases and is common among isolates from other sources, specifically retail poultry - a major source of human infection. In this study the antimicrobial susceptibility of isolates from a UK-wide survey of Campylobacter in retail poultry in 2001 and 2004–5 was investigated. The occurrence of phenotypes resistant to tetracycline, quinolones (ciprofloxacin and naladixic acid), erythromycin, chloramphenicol and aminoglycosides was quantified. This was compared with a phylogeny for these isolates based upon Multi Locus Sequence Typing (MLST) to investigate the pattern of antimicrobial resistance acquisition.

Results
Antimicrobial resistance was present in all lineage clusters, but statistical testing showed a non-random distribution. Erythromycin resistance was associated with Campylobacter coli. For all antimicrobials tested, resistant isolates were distributed among relatively distant lineages indicative of widespread acquisition. There was also evidence of clustering of resistance phenotypes within lineages; indicative of local expansion of resistant strains.

Conclusions
These results are consistent with the widespread acquisition of antimicrobial resistance among chicken associated Campylobacter isolates, either through mutation or horizontal gene transfer, and the expansion of these lineages as a proportion of the population. As Campylobacter are not known to multiply outside of the host and long-term carriage in humans is extremely infrequent in industrialized countries, the most likely location for the proliferation of resistant lineages is in farmed chickens.
Infrared thermography as an access pathway for individuals with severe motor impairments
Authors: Memarian Negar , Venetsanopoulos Anastasios , Chau Tom
Published: July 2021

Infrared thermography as an access pathway for individuals with severe motor impairments
Agent-based modeling of host-pathogen systems: The successes and challenges
Authors: Bauer Amy L. , Beauchemin Catherine A. A. , Perelson Alan S.
Published: July 2021

Agent-based models have been employed to describe numerous processes in immunology. Simulations based on these types of models have been used to enhance our understanding of immunology and disease pathology. We review various agent-based models relevant to host–pathogen systems and discuss their contributions to our understanding of biological processes. We then point out some limitations and challenges of agent-based models and encourage efforts towards reproducibility and model validation.
What can be learned from patient stories about living with the chronicity of heart illness? A Narrative Inquiry
Authors: Schwind Jasna , Fredericks Suzanne , Metersky Kateryna , Gaudit Porzuczek Victoria
Published: July 2021

Background: Patients’ illness stories are valuable information that supports person-centred care across the illness trajectory. Aims: To learn how older South Asian immigrant women experience living with heart illness long after discharge from hospital. Method: We used narrative inquiry, a personal experience method that explores and interprets lived and told stories through the three dimensions of experience. Design: Four participants, over the age of sixty, living with heart illness for over ten years, were invited to engage in narrative interview and Narrative Reflective Process. Outcomes: Giving patients voice, allows caregivers insight into the human experience of illness beyond hospitalization. Considering the increased migration of people around the globe, this knowledge is significant in provision of person-centred care. Implications: Person-centred care does not end with the hospitalization and outpatient clinics. Inter-disciplinary teams need to reconsider the trajectory of chronic illnesses and the care required throughout, especially for marginalized populations.
Exploring the interpersonal collaboration during the integration of diabetes teams into primary care.
Authors: Gucciardi Enza , Espin Sherry , Morganti Antonia , Dorado Linda
Published: July 2021

Background

Specialised diabetes teams, specifically certified nurse and dietitian diabetes educator teams, are being integrated part-time into primary care to provide better care and support for Canadians living with diabetes.

This practice model is being implemented throughout Canada in an effort to increase patient access to diabetes education, self-management training, and support. Interprofessional collaboration can have positive effects on both health processes and patient health outcomes, but few studies have explored how health professionals are introduced to and transition into this kind of interprofessional work.

Method

Data from 18 interviews with diabetes educators, 16 primary care physicians, 23 educators’ reflective journals, and 10 quarterly debriefing sessions were coded and analysed using a directed content analysis approach, facilitated by NVIVO software.

Results

Four major themes emerged related to challenges faced, strategies adopted, and benefits observed during this transition into interprofessional collaboration between diabetes educators and primary care physicians: (a) negotiating space, place, and role; (b) fostering working relationships; (c) performing collectively; and (d) enhancing knowledge exchange.

Conclusions

Our findings provide insight into how healthcare professionals who have not traditionally worked together in primary care are collaborating to integrate health services essential for diabetes management. Based on the experiences and personal reflections of participants, establishing new ways of working requires negotiating space and place to practice, role clarification, and frequent and effective modes of formal and informal communication to nurture the development of trust and mutual respect, which are vital to success.
The effect of muscle contusion on cortical bone and muscle perfusion following reamed, intramedullary nailing: a novel canine tibia fracture model
Authors: Koo Henry , Hupel Thomas , Zdero Rad , Tov Alexei , Schemitsch Emil H.
Published: July 2021

Background
Management of tibial fractures associated with soft tissue injury remains controversial. Previous studies have assessed perfusion of the fractured tibia and surrounding soft tissues in the setting of a normal soft tissue envelope. The purpose of this study was to determine the effects of muscle contusion on blood flow to the tibial cortex and muscle during reamed, intramedullary nailing of a tibial fracture.

Methods
Eleven adult canines were distributed into two groups, Contusion or No-Contusion. The left tibia of each canine underwent segmental osteotomy followed by limited reaming and locked intramedullary nailing. Six of the 11 canines had the anterior muscle compartment contused in a standardized fashion. Laser doppler flowmetry was used to measure cortical bone and muscle perfusion during the index procedure and at 11 weeks post-operatively.

Results
Following a standardized contusion, muscle perfusion in the Contusion group was higher compared to the No-Contusion group at post-osteotomy and post-reaming (p < 0.05). Bone perfusion decreased to a larger extent in the Contusion group compared to the No-Contusion group following osteotomy (p < 0.05), and the difference in bone perfusion between the two groups remained significant throughout the entire procedure (p < 0.05). At 11 weeks, muscle perfusion was similar in both groups (p > 0.05). There was a sustained decrease in overall bone perfusion in the Contusion group at 11 weeks, compared to the No-Contusion group (p < 0.05).

Conclusions
Injury to the soft tissue envelope may have some deleterious effects on intraosseous circulation. This could have some influence on the fixation method for tibia fractures linked with significant soft tissue injury.
Displacement of the Hip Center of Rotation After Arthroplasty of Crowe III and IV Dysplasia : A Radiological and Biomechanical Study
Authors: Abolghasemian Mansour , Samiezadeh Saeid , Jafari Davood , Bougherara Habiba , Gross Allan E , Ghazavi Mohammad T
Published: July 2021

To study the direction and biomechanical consequences of hip center of rotation (HCOR) migration in Crowe type III and VI hips after total hip arthroplasty, post-operative radiographs and CT scans of several unilaterally affected hips were evaluated. Using a three-dimensional model of the human hip, the HCOR was moved in all directions, and joint reaction force (JRF) and abductor muscle force (AMF) were calculated for single-leg stance configuration. Comparing to the normal side, HCOR had displaced medially and inferiorly by an average of 23.4% and 20.8%, respectively, of the normal femoral head diameter. Significant decreases in JRF (13%) and AMF (46.13%) were observed in a presumptive case with that amount of displacement. Isolated inferior displacement had a small, increasing effect on these forces. In Crowe type III and IV hips, the HCOR migrates inferiorly and medially after THA, resulting in a decrease in JRF, AMF, and abductor muscle contraction force.