bluuebunny/crossref_metadata_2025 huggingface dataset:
MANAGEMENT OF BUSINESS ORGANIZATION’S INFORMATION SYSTEM IN THE CONDITIONS OF DIGITAL TRANSFORMATION OF ECONOMY OF UKRAINE
Authors:   The Bohdan Khmelnytsky National University of Cherkassy, Nazarenko Sergey , Nosan Natalia ,   The Bohdan Khmelnytsky National University of Cherkassy
Published: May 2022

Nowadays information resources are one of the most important resources for effective functioning of organizations in market conditions, that are able to ensure its competitive position. Regardless of type of activity every company operates a large array of information, but the degree of its usefulness in management is different according to the development of information systems and technologies of enterprise. Therefore, effective operation of any enterprise as a whole requires accessible, timely and structured information provided by information system. Significant amount of circulating information, variety of formats for its presentation and dynamics of receipt require the development of new approaches to management, as traditional approaches are not able to cope with it. As a result, there is a need to improve and use new information systems. This is especially relevant in the context of activation the digital transformation of economy, which has a special impact on business environment not only in Ukraine, but also in the world over the past few years. Activation and globalization of these processes has an increasing impact on changes in the information space of every modern organization, which requires detailed scientific and theoretical research according to current state of socio-economic development of domestic society. The article considers the essence of information system of organization, its role in meeting the information needs of business entities in Ukraine. The main advantages of using information systems by business organizations are considered. The existing types of information systems in the conditions of transition to digital economy are indicated. The actual level of development of digital transformation in the national economy of Ukraine is presented, emphasizing the main restraining factors of the spread of digital technologies, in particular, in the private sector of economy. The main digital tools used in Ukrainian business to address key strategic and operational development goals are presented separating four main vectors: relationships with contractors, operating activities, product competitiveness and cooperation with the public sector.
СOMMUNICATION STRATEGY DEVELOPMENT ALGORITHM FOR B2C STARTUPS
Authors:   Chernihiv Polytechnic National University, Verbytska Anna , Babachenko Larysa ,   Chernihiv Polytechnic National University
Published: May 2022

This article proposes an author's algorithm for developing a communication strategy for B2C startups, including: communication audit of B2C startup, setting goals and objectives of the communication strategy (business goals, marketing goals, communication goals); analysis of the business model of the startup (defining of the life cycle of the startup); defining of the target audience; development of communication messages for each segment in accordance with the profile; definition of startup communication tools; definition of communication channels of the startup; development of a communication plan; media plan development; evaluation of the effectiveness of the communication strategy. The proposed algorithm focuses on the in-depth analysis of the profile of the consumer's personality, which allows to predict behavioural responses in conditions of uncertainty and create an effective communication strategy B2C startup.
FULFILMENT: THEORETICAL AND APPLIED ASPECTS
Authors:   National University Lviv Polytechnic, Hirna Olha , Kobylyukh Oksana ,   National University Lviv Polytechnic
Published: May 2022

The article reveals the main trends in the development of e-commerce in the context of the COVID-19 pandemic. The relevance of using fulfillment as one of the key elements of overcoming the negative consequences for online stores in today’s conditions is emphasized. The essence of the concept of “fulfillment”, which helps to develop trade and increase sales of small shops and large virtual trading platforms, is revealed. The essence of the main business processes on which it is focused is acceptance of production, features of storage of the goods, a complete set of the order, packing of the goods, management of returns. Based on the structural-logical scheme, the process of fulfillment implementation is presented. The target audience of its operation is outlined: online stores, manufacturers and wholesale suppliers, large importers, and exporters. The expediency of using fulfillment depending on the volume of the order is given. Prices for fulfillment services are presented in accordance with evaluation methods: a monthly subscription, fixed fee for each order, and percentage of sales. Along with the negative factors of fulfillment for the online store (such as lack of free access to the warehouse, errors in completing the goods, difficulties with paperwork, guaranteed stock), there are positive aspects: savings on overhead costs, simplification, and acceleration of order processing, warehousing stock, instant shipment, efficient operation of the call center, acceptance of payment and refund. The positive elements of Amazon’s use of fulfillment at the international level have been revealed. In the Ukrainian market, Zammler’s and Epicenter K’s characteristics are described. The operation of small-scale fulfills described in detail on the example of Cherdak Company, and the main points of Glovo microfulfilms in the markets of the European Union and Ukraine are presented. Based on the monitoring of the structure of fulfilling services of the main players in the foreign and domestic markets, it is emphasized that with the successful use of fulfillment elements, companies of different levels of development are able to overcome the harmful effects of the pandemic and maintain leadership in the services market.
Nitric acid and hydrogen peroxide in the digestion of milk and cheeses for the detection of heavy metals
Authors: Castro Gonzalez Numa , Pérez-Sato Marcos , Soni-Guillermo Eutiquio , Valencia-Franco Edgar , Carmona-Victoria Martín , Calderón-Sánchez Francisco
Published: May 2022

The content of arsenic (As), cadmium (Cd), copper (Cu), chromium (Cr), lead (Pb) and zinc (Zn) in milk and cheeses was determined, comparing the use of nitric acid and a mixture of nitric acid and hydrogen peroxide (HNO3 + H2O2) in acid digestion. The milk was collected from storage tanks in localities of Huejotzingo and cheeses in Santa Ana Xalmimilulco, Huejotzingo, Puebla. Digestion was carried out in a CEM MarsX microwave. The determination was in an ICP OES. As it showed (p <0.01) when using HNO3 (0.13 mg kg-1) with respect to the mixture. The Cd, Zn and Pb showed (p <0.01), with the use of the mixture with respect to HNO3. The content of Cd, As, Cu and Cr in the cheese there was difference (p <0.01) when using HNO3 compared to the mixture. This shows that there is specificity for metal detection, with HNO3 being the most efficient
Visionary Leadership and Employee Quality in the Public Service Sector
Authors: UTOMO Wahyu Abdillah , UDIN Udin , HARYONO Siswoyo
Published: May 2022

For the continuity of delivery of public services. A visionary leader prioritizes visions and strategies for future success by observing opportunities and threats. Visionary leaders can relate directly to employees to produce high quality work. This study aims to identify the relationship between visionary leadership and the quality of employees in the public service sector. A qualitative research method was used to provide an explanation related to the phenomena through a deep analysis of the data. This study uses manuscript bibliographic data sources obtained through Google Scholar and was analyzed using a systematic literature review through a bibliometric approach. The results of the research indicate that visionary leadership is directly and significantly related to the quality of employees in the public service sector. Therefore, visionary leadership can be a good choice in determining a leadership style to achieve the vision and strategy for an organization's success.
COVID-19 Pandemic, Real Effective Exchange Rate and Foreign Direct Investment Inflows: Evidence from Morocco, Turkey and Egypt
Authors: El Rhadbane Ayyoub Ben , Moudden Abdeslam El
Published: May 2022

This paper aims to empirically study the impact of real effective exchange rate (REER) volatility in different exchange rate arrangements for the 1990–2020 period and the impact of the Covid-19 pandemic on foreign direct investment (FDI) inflows to Morocco, Turkey and Egypt. Economic growth, gross fixed capital formation, economic openness, and inflation volatility are economic quantities that also specify the model. The autoregressive conditional heteroscedasticity model was used to measure the annual volatility of REER and inflation, and the cointegration bounds test approach via the scaled lag autoregressive model. The estimation results show that FDI inflows responded negatively to real effective exchange rate volatility at the 10% level in Morocco and positively at the 1% level in Turkey at lag (2). In the short run, according to the estimation results obtained, it seems that the Covid-19 pandemic did not have a negative impact on FDI inflows at the 1% level in Morocco, and also did not significantly affect Turkey. In Egypt, the ARDL model was shown to be invalid following the validity tests performed for reasons clarified in this paper.
Transferencia de conocimiento científico sobre variabilidad climática en entornos rurales (comunidad de Boquerón, Jagua de Ibirico)
Authors: Cotes Daniel , Noriega Arístides , Díaz Muegue Luis Carlos , Castellanos Paige
Published: May 2022

Boquerón es un corregimiento ubicado en medio de grandes proyectos de extracción de carbón a cielo abierto en el centro del Departamento del Cesar. En el pasado su principal actividad económica fue la agricultura junto con la pesca, pero adicionado a la transformación del territorio por la minería y sumado a los desafíos climáticos que se intensifican en disponibilidad recursos suelo y agua conforman un panorama preocupante para sus habitantes. Movidos por estas dificultades se conformó una estrategia, “Programa de movilidad académica para la transferencia de conocimiento científico a las comunidades rurales para la construcción de la paz”, desarrollado por estudiantes y profesores de Fundación Universitaria del Área Andina (Valledupar), Jorge Tadeo Lozano (Bogotá) y Penn State University (Estados Unidos), en donde se identificaron las condiciones socioeconómicas de la comunidad rural de Boquerón a partir del uso de metodologías utilizadas por investigadores rurales, desarrollo de talleres con representantes de la comunidad y expertos temáticos locales; además de plantear mesas de discusión para estructurar soluciones a los desafíos territoriales. El ejercicio permitió definir una estructura de trabajo para tratar los cambios ambientales generados por la industria agrícola, extractiva y el cambio climático en el territorio.
Las dinámicas socio-cognoscitivas en un sector conocimiento-intensivo. Nahuelsat S.A. (1993-2007)
Authors: Cáceres Yamila Noely
Published: May 2022

En este artículo se analizaron las dinámicas socio-cognoscitivas que favorecieron la emergencia y el desarrollo de la operación de satélites geoestacionarios a fines del siglo xx en Argentina. Para ello, se recuperó la experiencia de la empresa privada Nahuelsat s.a. entre 1993 y 2007. El período bajo análisis comprende desde la creación de la empresa para ocupar las posiciones orbitales asignadas a la Argentina por la Unión Internacional de Telecomunicaciones (uit), hasta la cesión de sus activos financieros, edilicios y humanos a Argentina Satelital s.a. (arsat s.a.), una empresa pública argentina constituida en el año 2006. Durante este período se establecieron las condiciones sociales y cognitivas que hicieron posible la operación local de satélites de telecomunicaciones, el desarrollo de nuevos satélites y la institucionalización de nuevos saberes.
De libros prohibidos, datos y políticas culturales. Cuantificar el impacto de las bibliotecas
Authors: Ruiz Ruiz David
Published: May 2022

Las bibliotecas públicas tienen un impacto económico y social en la sociedad y contamos con mecanismos y herramientas para medirlo, de manera que los gastos en bibliotecas suponen una inversión cuyo retorno es perfectamente cuantificable. Para ello nos acercamos al estudio que se hizo en 2016 en el marco de las bibliotecas de Navarra El valor de las bibliotecas y accesible desde la web http://www.elvalordelasbibliotecas.es/. Este trabajo ofrece una herramienta práctica para que tanto las bibliotecas puedan calcular su rentabilidad como para que los usuarios puedan acceder al “coste” de los servicios usados.

No obstante, el análisis cuantitativo del coste no puede hacernos perder la perspectiva de la función social de las bibliotecas como espacios de libertad que hemos de garantizar en un momento en el que parece que ésta se está “cercenando” en algunos espacios determinados a raíz de ciertas prohibiciones de libros.
Perancangan Aplikasi Pelayanan Data Penjualan Toko Optik Berbasis Web dengan Menggunakan Metodologi Rational Unified Process
Authors: Supriatna Asep Deddy , Fatimah Dini Destiani Siti , Nurrohman Irpan
Published: May 2022

Pelayanan adalah salah satu bagian terpenting dari sebuah penjualan terhadap suatu produk, karena dapat mempengaruhi tingkat penjualan itu sendiri. Saat ini pelayanan dilakukan secara offline saja, dan itu tidak efektif jika terjadi antrian sehingga dapat memberikan kesan kurang baik terhadap pelanggan. Untuk itu perlu adanya pengoptimalan dari segi pelayanan terhadap pelanggan, agar membuat pelanggan menjadi puas terhadap pelayanan yang diberikan. Dengan adanya aplikasi pelayanan penjualan berbasis web diharapkan mampu mengoptimalkan pelayanan terhadap pelanggan agar kebutuhan pelanggan terpenuhi serta terlayani dengan optimal sehingga memberikan kesan yang baik terhadap pelanggan dengan pelayanan yang diberikan. Sedangkan untuk pengembangan aplikasi penulis menggunakan metodologi yang dinamakan Rational Unified Procces yang tahapannya yaitu inception, elaboration, dan contraction kemudian menggunakan pemodelan Unified Modelling Languange. Berdasarkan penelitian yang telah dilakukan dapat disimpulkan aplikasi pelayanan data penjualan ditoko optik berbasis web mampu mengoptimalkan pelayanan penjualan guna memberikan kesan yang baik kepada pelanggan, serta untu menaikan penjualan lewat pelayanan yang baik.
Sistem Pendukung Keputusan Penerimaan Siswa Baru Berbasis Web Menggunakan Metode Matching Profile
Authors: Nuraeni Fitri , Supriatna Asep Deddy , Febriana Rizky
Published: May 2022

Penerimaan siswa baru merupakan gerbang awal yang harus dilalui peserta didik dan sekolah didalam penyaringan obyek-obyek pendidikan. Peristiwa penting bagi suatu sekolah, karena peristiwa ini merupakan titik awal yang menentukan kelancaran tugas suatu sekolah. SPK merupakan sistem berbasis komputer interaktif yang membantu pengambil keputusan (manajer) memanfaatkan data dan model untuk menyelesaikan permasalahan yangsemi/ tidak terstruktur, Maka dibuatlah Perancangan Sistem Pendukung Keputusan Penerimaan Siswa Baru Berbasis Web Menggunakan Metode Matching Profile, dimana dalam perancangan Sistem informasi penerimaan peserta didik baru ini menggunakan metodologi Rapid application development (RAD) dengan memiliki 5 tahapan perancangan seperti Bussiness Modelling, Data modelling, process modelling, application generation dan testing & turnover dengan menggunakan Bahasa pemrograman PHP serta Mysql untuk databasenya. Dimana proses penyeleksian penerimaan siswa baru harus di dukung dengan pemanfaatan teknologi informasi yang akan mempermudah petugas dalam menyeleksi calon siswa baru, serta membantu dalam penentuan penerimaan siswa baru sesuai kriteria, mengurangi human error dan keamanan data lebih terjamin karena disimpan dalam database.
Resection Via Transpalatal Approach of Huge Solitary Fibrous Tumor Involving Pterygopalatine Fossa
Authors: Gwak Jang Wook , Yi Sea Eun , Lee Yeong Ju , Yu Myeong Sang
Published: May 2022

Solitary fibrous tumors (SFTs) are spindle-cell tumors that rarely arise within extrathoracic area. Massive SFTs involving the pterygopalatine fossa are extremely rare and surgical excision represents a multidisciplinary surgical challenge. We present a case of 64-year-old female with a huge mass originating from the pterygopalatine fossa invading the skull base. Distinct microscopic findings and a positive nuclear staining of signal transducer and activator of transcription 6 (STAT-6) pathologically confirmed SFT. The right internal maxillary artery branch was embolized preoperatively and a surgical excision was performed through a combined technique of transpalatal, mid-facial degloving and endoscopic approach. Postoperative radiotherapy successfully removed the remnant tumor adjacent to the carvenous sinus. Follow- up MR images showed no evidence of recurrence for two years. To our knowledge, there has been no previous report of the successful treatment of this vast extent of SFT in the pterygopalatine region via endoscopic-external-combined approach and radiotherapy.
A Comparison of Endolymphatic Sac Decompression and Intratympanic Gentamicin for Treatment of Meniere’s Disease
Authors: Joo Hye Ah , Jeong In Seong , Kang Woo Seok , Park Hong Ju , Chung Jong Woo , Ahn Joong Ho
Published: May 2022

Background and Objectives Meniere’s disease (MD) is primarily managed by lifestyle and dietary changes. There are several non-medical treatment options for medically intractable MD; however, treatment results still remain controversial. This study aims to review the treatment outcome of endolymphatic sac decompression (ESD) and intratympanic gentamicin (ITG) for MD refractory to medical management.Subjects and Method The medical records of 50 patients, diagnosed with definite MD intractable to medical management, who underwent ESD or ITG from 2010 to 2020 at a tertiary referral hospital, were retrospectively reviewed. ESD was first considered in patients with serviceable hearing (pure tone audiometry average value less than 50 dB, speech discrimination score of 50% or greater). One-year post-treatment audiological changes and vertigo control were reviewed and compared between the two groups.Results Fifty patients (ears) were enrolled in this study (ESD, n=27; ITG, n=23). There was a post-treatment hearing gain (2.3 dB HL) in the ESD group (p=0.509), while there was an overall post-treatment hearing decline (2.2 dB HL) in the ITG group (p=0.178), with no significant difference between two groups regarding hearing change (p=0.212). Regarding vertigo control, 66.6% and 56.5% patients in the ESD and ITG groups, respectively, were classified as vertigo class A or B, with statistically significant difference between both groups (p=0.027).Conclusion ESD conferred better post-treatment vertigo control than ITG, but there were no significant hearing changes in both groups. ESD is an effective treatment for patients with medically intractable MD who has serviceable hearing.
The Prediction of Drying Performance of Banana Rings Dried By Osmo-solar Dehydration Method
Authors: YILDIZ Zehra , ALCAN Veysel
Published: May 2022

Solar drying is known as the oldest and most common traditional food preservation method. However, if the product is indirectly contacted with the sun light, there is negative effect in the color and nutrient values of the product. Solar dryers have been developed to utilize the heat effect of the sun to solve these problems. It can be used in combination with osmotic dehydration to increase the efficiency of the solar drying process. Osmotic dehydration is applied as a pretreatment technique in the drying process. The pretreatments to be applied before drying have important effects on the quality and operating cost of the product to be dried. In addition, the osmotic dehydration pretreatment enables to shorten the drying time and increase the drying potential. In this study, bananas with high drying temperature and high moisture content were sliced into 3 mm rings, then osmotic dehydration pre-drying was applied, and then they were dried in a solar tray dryer. Sucrose and citric acid solution in 2.5%, 5%, 7.5% and 10% (w/v) concentrations were used for osmotic dehydration treatment. In addition, samples without osmotic dehydration were dried in a solar dryer to determine the effect of pretreatment. The input variables of the drying process are solution concentration (0%, 2.5%, 5%, 7.5% and 10%), type of solution (sucrose solution and citric acid solution), osmotic dehydration time (10, 30, 60 and 90 min) and sun drying time (60, 120, 180, 240 and 300 min). Output variables were chosen as moisture ratio and shrinkage rate. The results clearly showed that both the moisture ratio and the shrinkage ratio have increased due to increased solar dryer time, solution concentration and immerse time. Osmotic dehydration was found to be effective in dried banana rings in the solar tray dryer. Gradient Boosting Machine (GBM) was used to model the drying conditions and the model was successful. The correlation coefficient (R2) values of the GBM model were respectively found as 0.94 and 0.83 for the moisture ratio and the shrinkage ratio.
PENGEMBANGAN LEMBAR KERJA SISWA BERBASIS CORE (CONNECTING, ORGANIZING, EXTENDING, DAN REFLECTING) PADA MATERI SISTEM PERSAMAAN LINIER DUA VARIABEL
Authors: Zamzam Kenys Fadhilah , Hamandika Orvinus Ndilu
Published: May 2022

Student worksheets (LKS) are student guides in solving problems. LKS based on CORE (Connecting, Organizing, Extending, and Reflecting) on the material of a two-variable equation system had advantages in presenting the material and had an attractive appearance. The development model used ADDIE model. The subjects of this study were 20 students of SMAN 1 Nggaha Ori Angu. The data collection process used an instrument in the form of a validation sheet with the aim of measuring the validity of the LKS, post-test to determine student learning outcomes and student responses to the LKS developed to determine the effectiveness of the LKS. The results of data analysis showed that from the two validators the average value was 3.32 which showed the valid criteria. The percentage of students' average completeness score was 78%. Based on the established criteria, it can be said that students had good mastery of the SPLDV material. The student response questionnaire data obtained a percentage of 85.7%, so based on the criteria it was concluded that students showed a positive response to the developed LKS. Overall, the CORE-based LKS on SPLDV material was effectively used in the learning process.
Intra- and inter-population variation in sensitivity of migratory sockeye salmon smolts to phenological mismatch
Authors: Wilson SM , Patterson DA , Moore JW
Published: May 2022

Certain consumer traits may influence sensitivity to phenological mismatches between consumers and their prey, and understanding the variation in these traits across or within populations could be helpful in predicting if and how a consumer population will respond to climate change. Here, we quantify intra- and inter-population variation in traits of sockeye salmon (Oncorhynchus nerka) smolts that may influence sensitivity to starvation associated with phenological mismatch. We asked 2 questions: (1) What is the magnitude of intra- and inter-population variation in physical and energetic condition at different stages of emigration? (2) How would this trait influence survival during periods of starvation? We collected sockeye salmon smolts from 3 populations before and 8 populations after riverine migration within the Skeena River watershed, BC, and measured condition-specific traits such as size and energetic condition. We discovered among-population variation was lower after migration: before migration traits differed between populations, but after-migration traits were more similar across populations. We estimated starvation resistance, the number of days until predicted death, using a previously developed model. Mean starvation resistance varied between 18 and 33 d across populations and varied within each population to as low as 6 d. These results reveal substantial within- and across-population sensitivity to starvation which may be associated with phenological mismatch. Thus, factors other than phenology (e.g. freshwater ecosystem dynamics that influence smolt condition) have the potential to influence sensitivity to phenological mismatch and, potentially, marine survival.
TRICHOTILLOMANIA WITH GIANT GASTRIC TRICHOBEZOAR IN A FEMALE CHILD: A CASE REPORT
Authors: Fadhil Abbas Walaa , Olga Borisovna Tamrazova , Anton Vladimirovich Molochkov , Alexander Valerievich Dzyadchik , Antonina Sergeevna Stadnikova
Published: May 2022

Trichotillomania is defined by the Diagnostics and Statistic Manual of Mental Disorders (DSM-5) as an individual repetitively pulling of their own hair, which may be an unconscious action or intentional. The disease is considered one of the anxiety disorders as it has some obsessive-compulsive features. Many patients with this disorder go to a dermatologist for the first time with a complaint of hair loss (alopecia), and many of them deny the self-pulling behaviour. In rare circumstances, this psychological problem may coexist with a complication called gastric trichobezoar, like in this unusual case presentation, which is an accumulation of the patient’s hair in their stomach. It can be huge, presenting as a ‘tail’ extending into the duodenum and leading to what is referred to in the literature as ‘Rapunzel syndrome’. Gastric trichobezoars are most often seen in teenage females. Trichophagia has only been previously confirmed in one-third of these patients, but this is usually a late presentation, occurring after much hair eating for many years.
Pressure Fluctuation Characteristics Of Mixed-Flow Pump Under Near Stall Condition
Authors:   Jiangsu University, Li Wei , Lu Dele ,   Jiangsu University, Ji Leilei ,   Jiangsu University, Zhou Ling ,   Jiangsu University, Agarwal Ramesh K. ,   Washington University in St. Louis
Published: May 2022

When the rotating stall occurs in a mixed-flow pump, the periodic generation and disappearance of the stall core often cause unstable pressure pulsation. Based on the k-ε turbulence model, the time domain and frequency domain responses of the pressure fluctuation of the mixed-flow pump with 3 kinds of different flange clearances are studied. The results show that the time-domain curves of pressure fluctuation at each monitoring point show periodic changes near stall condition, but the peak and trough characteristics of impeller rotation are not obvious. There is a large phase difference between adjacent monitoring points, accompanied by a strong pressure drop. When the flange clearance is 0.5 mm and 0.8 mm, the time domain curve of pressure fluctuation has 2 wave troughs in one cycle. In the near stall condition, the main frequency of pressure fluctuation at 3 monitoring points in the same channel is 0.2 times the rotational frequency, i.e. stall frequency. In addition, the main frequency amplitude in the middle of the outlet is the largest, and the larger the gap is, the larger the main frequency amplitude is.
A Parametric Study Of Circumferential Range Of Inlet Distortions On Transonic Rotor Stall Process
Authors:   School of Mechanical Engineering, Shanghai Jiaotong University, Guoming Zhu Guoming Zhu , Yang Bo ,   School of Mechanical Engineering, Shanghai Jiaotong University, Song Moru ,   School of Mechanical Engineering, Shanghai Jiaotong University, Zhang Shuyi ,   School of Mechanical Engineering, Shanghai Jiaotong University, Xie Hong ,   School of Mechanical Engineering, Shanghai Jiaotong University
Published: May 2022

The distortions, such as total pressure distortion in circumferential and radial directions, generated by low speed flow cell upstream is a common phenomenon at the inlet of an axial compressor. Nonuniform inflow can extremely affect the performance and the stability of compressor, and needs to be considered during the design of a turbojet engine. In this paper, a distortion model is proposed to provide an option to simulate upstream low speed flow. And then, a series of full annulus, unsteady, computational fluid dynamics (CFD) simulations is conducted in this study to analyze each influence of three kind of total pressure distortions, covering 60, 120 and 180-deg sectors above 0.7 span at the inlet boundary respectively, on the performance and the stability of NASA Rotor 67. And the results also present how the rotating stall is induced and develops under different inflow conditions.
Research of laws and prediction of axial-flow compressor characteristics based on data driven
Authors:   School of Power and Energy, Northwestern Polytechnical University, Tantao Liu Tantao Liu , Gao Limin ,   School of Power and Energy, Northwestern Polytechnical University, Feng Xudong ,   Aero Engine Corporation of China, Sichuan Gas Turbine Establishment
Published: May 2022

The performance maps of axial-flow compressors are critical to the operation and design of gas turbines. To explore the inherent laws of axial-flow compressors performance map, more than 50 axial-flow compressors’ maps were studied based on data analysis and thermodynamic principles. By introducing a variety of thermodynamic and mechanical parameters into the performance lines, relations between different quantities of compressors were built from three aspects which are peak efficiency lines, near-surged zones and near-choked zones. The relations between compressor characteristic parameters and design performance indexes were found and the prediction algorithm was developed to predict performance of compressors based on design performance indexes and performance parameters. It shows that there are linear relations between thermodynamics parameters within working speed range. The performance parameters of compressors are obvious relative with design total pressure ratio and little relative with design efficiency. The prediction algorithm can predict the performance map of compressors well just relied on design performance indexes and performance parameters without blades geometry information.
Accounting aspect of public finance management in the field of science
Authors:   SESE “The Academy of Financial Management”, KORYTNYK Liliya
Published: May 2022

The article is devoted to the study of key approaches to the creation of a modern mechanism of public finance management in the field of science in Ukraine on the basis of accounting information about the real cost of research and development. The state of financing the sphere of science is analyzed, and negative trends are shown in the structure of public expenditures that do not contribute to the development of the scientific potential of our state. It has been determined that financing of subjects of scientific - technical activities should be carried out on the basis of a reliably determined cost of public services provided by them. It has been substantiated that the cost price as an indicator of the volumes, directions and quality of the use of budgetary funds should become the basis for determining the amount of government funding and establishing a contractual price for research and development. It has been shown that in the conditions of the declared European integration direction of the development of domestic science, Ukrainian subjects of scientific and scientific-technical activities function in the absence of a sectoral normative legal act on the formation of the cost price of scientific research and scientific-technical (experimental) developments. It is shown that in order to implement state policy to enhance domestic scientific and scientific -technical activities and integration into the European Research Area, it is necessary to agree on approaches to mechanisms for the distribution of budgetary funding and develop a unified regulatory framework for planning, accounting for research and development and calculating thе cost price. This will contribute to the formation of unified principles for determining the cost of scientific re and scientific - technical (experimental) developments to create a modern effective mechanism for managing public finances in the field of science.
The January 6 Insurrection and America's Standing in the World: Natural Experimental Evidence from Five Unexpectedly Interrupted Public Opinion Surveys
Authors: van Noort Sam
Published: May 2022

American geopolitical power partly relies on foreign public support for its leadership. Pundits worry that this support is evaporating now that the United States---which claims to be the world's beacon of democracy---has itself experienced democratic backsliding. I provide the first natural experimental test of this hypothesis by exploiting that the January 6 insurrection of the U.S. Capitol unexpectedly occurred while Gallup was conducting nationally representative surveys in India, Indonesia, Malaysia, Romania, and Vietnam. Because Gallup recruits respondents using random digit dialing I can identify the effect of the January 6 insurrection by comparing U.S. leadership approval among respondents that were interviewed just before, and just after, January 6, 2021. Surprisingly, I find that the insurrection had no effect on U.S. approval abroad. This suggests that American soft power may rely significantly less on America actually living up to its "beacon of democracy" mantra than typically presumed.
Pendampingan Pengelolaan Ibu Hamil dengan Kekurangan Energi Kronik dan Bayi Berisiko Stunting
Authors: Anis Setyowati  , Ratnawati Lina , Sholichah Rizka Mar’atus
Published: May 2022

Pregnant women with Chronic Energy Deficiency and low nutrition knowledge are at risk of pregnancy with anemia. Inhibited fetal growth (IPM) and LBW delivery can increase the risk of stunting. The purpose of this activity was to deal with SEZ problems in pregnant women, babies who are at risk of stunting, and lack of nutrition knowledge. The method used was assistance to pregnant women with Chronic Energy Deficiency until the mother gives birth by providing additional foods high in calories and protein, iron, calcium and folic acid supplementation, as well as education through lectures and discussions. The location was in Puncu District, Kediri Regency with 37 pregnant women with Chronic Energy Deficiency with gestational age of 23-40 weeks. There was an increase in the average weight of pregnant women by 8.9 kg, uterine fundal height increased by an average of 14.06 cm, upper arm circumference increased by an average of 3.9 cm, Hb levels increased by an average of 1.74gr%, Mother's knowledge about nutrition and exclusive breastfeeding increased, breastfeeding skills increased, the baby's weight and upper arm circumference were in the normal category. Assistance for pregnant women with Chronic Energy Deficiency and babies at risk of stunting can improve maternal health during pregnancy and prevent babies from experiencing stunting.
 
ABSTRAK
Ibu hamil dengan status gizi KEK dan pengetahuan rendah tentang gizi berisiko terhadap kehamilan dengan anemia. Pertumbuhan janin terhambat (PJT) dan persalinan BBLR dapat meningkatkan risiko stunting pada bayi. Tujuan kegiatan ini adalah menangani masalah KEK pada ibu hamil, bayi yang berisiko stunting, rendahnya pengetahuan tentang gizi. Metode yang digunakan adalah pendampingan kepada ibu hamil KEK sampai ibu melahirkan dan bayinya berusia 3 bulan dengan memberikan makanan tambahan tinggi kalori dan protein, suplementasi tablet tambah darah, kalsium dan asam folat, serta edukasi dengan ceramah dan diskusi. Lokasi di Kecamatan Puncu Kabupaten Kediri dengan 37 ibu hamil KEK dengan usia kehamilan 23-40 minggu. Terdapat peningkatan rerata berat badan ibu hamil sebesar 8,9 kg, tinggi fundus uteri meningkat rata-rata sebesar 14,06 cm, lingkar lengan atas meningkat rata-rata 3,9 cm, kadar Hb meningkat rata-rata sebesar 1,74gr%, pengetahuan ibu tentang gizi dan ASI Eksklusif meningkat, keterampilan menyusui meningkat, berat badan dan lingkar lengan atas bayi dalam kategori normal. Pendampingan ibu hamil KEK dan bayi berisiko stunting dapat meningkatkan kesehatan ibu selama kehamilan dan mencegah bayi mengalami stunting.
Modelo Pedagógico Etnoeducativo Emancipador “Champalanca Pedagógica” generador de integración intercultural-territorial en la IE la Unión de Bajirá-Chocó
Authors: Ravelo Mendez Reisner De Jesús , Bailarin Mirian Monterrosa
Published: May 2022

Con este artículo se busca comprender el modelo pedagógico etnoeducativo emancipador “Champalanca Pedagógica” y sus incidencias en la integración intercultural territorial en la IE la Unión de Bajirá – Chocó. Este se desarrolló desde la metodología cualitativa, con enfoque descriptivo, donde se aplicaron las técnicas del taller pedagógico y las entrevistas semiestructuradas a través de la presencialidad remota (vía audio WhatsApp) para darle cumplimiento al distanciamiento social por la pandemia del COVID-19. Como resultado se identificaron cuatro (4) categorías en la aplicación del modelo en mención: pedagogía, convivencia, conflicto, contexto, logrando comprender: Primero, los componentes del modelo. Segundo, las prácticas de aula por los docentes en la institución mencionada. Tercero, las dificultades y fortalezas presentadas en la implementación de dicho modelo champalanca pedagógica en relación a educación en y desde la interculturalidad y la diversidad. Finalmente se corrobora que el modelo Champalanca pedagógica es generador de integración intercultural en la IE la Unión de Bajirá y se recomienda la implementación de la educación intercultural como estrategia de integración intercultural en un contexto culturalmente diverso.
A One-Step Electrochemical Aptasensor Based on Signal Amplification of Metallo Nanoenzyme Particles for Vascular Endothelial Growth Factor
Authors: Mei ChenYang , Zhang Yuanyuan , Pan Luting , Dong Bin , Chen Xingwei , Gao Qingyi , Xu Hang , Xu Wenjin , Fang Hui , Liu Siyu , McAlinden Colm , Paschalis Eleftherios I. , Wang Qinmei , Yang Mei , Huang Jinhai , Yu A-Yong
Published: May 2022

In this study, a one-step electrochemical aptasensor was developed to detect the biomarker vascular endothelial growth factor (VEGF), an important protein in the pathogenesis of many retinal diseases, including age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, and retinal vein occlusion. The aptamer has a good affinity and can rapidly identify and capture VEGF based on its unique structure. We designed a VEGF aptasensor based on the aptamer recognition and complex metallo nanoenzyme particles as an electron exchange center and bridge between capture DNA and electrode. The aptamers maintained the hairpin structure to avoid nonspecific surface adsorption and expose the capture sequence outwards when the target was inexistent. Conversely, the aptamers opened the hairpin structure to release space to accomplish binding between VEGF and DNA, resulting in increased impedance. The performance of the electrochemical aptasensor is detected by electrochemical impedance spectroscopy (EIS). The limit of detection by EIS was as low as 8.2 pg ml−1, and the linear range was 10 pg ml−1–1 μg ml−1. The electrochemical aptasensor also showed high specificity and reproducibility.
Engineering Multifunctional Hydrogel With Osteogenic Capacity for Critical-Size Segmental Bone Defect Repair
Authors: Zheng Shaowei , Zhong Haobo , Cheng Hao , Li Xu , Zeng Guowei , Chen Tianyu , Zou Yucong , Liu Weile , Sun Chunhan
Published: May 2022

Treating critical-size segmental bone defects is an arduous challenge in clinical work. Preparation of bone graft substitutes with notable osteoinductive properties is a feasible strategy for critical-size bone defects. Herein, a biocompatible hydrogel was designed by dynamic supramolecular assembly of polyvinyl alcohol (PVA), sodium tetraborate (Na2B4O7), and tetraethyl orthosilicate (TEOS). The characteristics of the supramolecular hydrogel were evaluated by rheological analysis, swelling ratio, degradation experiments, and scanning electron microscopy (SEM). In in vitro experiments, this TEOS-hydrogel had self-healing property, low swelling rate, degradability, good biocompatibility, and induced osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) by upregulating the expression of Runx-2, Col-1, OCN, and osteopontin (OPN). In segmental bone defect rabbit models, the TEOS-containing hydrogel accelerated bone regeneration, thus restoring the continuity of bone and recanalization of the medullary cavity. The abovementioned results demonstrated that this TEOS-hydrogel has the potential to realize bone healing in critical-size segmental bone defects.
A Potential Target for Diabetic Vascular Damage: High Glucose-Induced Monocyte Extracellular Vesicles Impair Endothelial Cells by Delivering miR-142-5p
Authors: Zhang Rui , Niu Shuai , Rong Zhihua , Li Fengshi , Ni Leng , Di Xiao , Liu Changwei
Published: May 2022

Endothelial dysfunction is a key accessory to diabetic cardiovascular complications, and the regulatory role of the extracellular vesicles (EVs) from the innate immune system is growing. We tested whether EVs derived from high glucose-induced monocytes could shuttle microRNAs and impair endothelial cells. EVs from high glucose- and basal glucose-treated THP-1 cells (HG-THP-1 EVs and BG-THP-1 EVs) were isolated and identified. After coculture with THP-1 EVs, human umbilical vein endothelial cells (HUVECs) were tested by proliferation, migration, reactive oxygen species (ROS) detection assays, and western blot for Nrf2/NLRP3 signaling. MiR-142-5p was predicted by miRNAs databases and further verified by RT–qPCR and dual-luciferase reporter gene assays that inhibit Nrf2 expression. The regulation of miR-142-5p in HUVECs was further evaluated. A type 1 diabetes mellitus (T1DM) mouse model was developed for miR-142-5p inhibition. Aorta tissue was harvested for hematoxylin-eosin staining and immunohistochemistry of interleukin-1β (IL-1β). Compared to BG-THP-1 EVs, HG-THP-1 EVs significantly reduced migration and increased ROS production in HUVECs but did not affect proliferation. HG-THP-1 EVs induced suppression of Nrf2 signaling and NLRP3 signaling activation. RT–qPCR results showed that HG-THP-1 EVs overexpressed miR-142-5p in HUVECs. The transfection of miR-142-5p mimics into HUVECs exhibited consistent regulatory effects on HG-THP-1 EVs, whereas miR-142-5p inhibitors demonstrated protective effects. The miR-142-5p antagomir significantly reduced the IL-1β level in T1DM aortas despite morphological changes. To conclude, miR-142-5p transferred by high glucose-induced monocyte EVs participates in diabetic endothelial damage. The inhibition of miR-142-5p could be a potential adjuvant to diabetic cardiovascular protection.
Epigenetic Regulation of Endothelial Cell Lineages During Zebrafish Development—New Insights From Technical Advances
Authors: Panara Virginia , Monteiro Rui , Koltowska Katarzyna
Published: May 2022

Epigenetic regulation is integral in orchestrating the spatiotemporal regulation of gene expression which underlies tissue development. The emergence of new tools to assess genome-wide epigenetic modifications has enabled significant advances in the field of vascular biology in zebrafish. Zebrafish represents a powerful model to investigate the activity of cis-regulatory elements in vivo by combining technologies such as ATAC-seq, ChIP-seq and CUT&Tag with the generation of transgenic lines and live imaging to validate the activity of these regulatory elements. Recently, this approach led to the identification and characterization of key enhancers of important vascular genes, such as gata2a, notch1b and dll4. In this review we will discuss how the latest technologies in epigenetics are being used in the zebrafish to determine chromatin states and assess the function of the cis-regulatory sequences that shape the zebrafish vascular network.
Topographic Response of Hinterland Basins in Tibet to the India–Asia Convergence: 3D Thermo-Mechanical Modeling
Authors: Zhang Pengpeng , Chen Lin , Xiao Wenjiao , Zhang Ji’en
Published: May 2022

A number of basins have developed in Tibet since the early stages of the India–Asia collision, and now, they have become integral parts of the Tibetan Plateau. Geophysical and geochemical data reveal that these basins are currently characterized either by strong or weak basements. However, it remains unclear how these hinterland basins evolved during the India–Asia collision and how they affected the post-collisional growth of the Tibetan Plateau. Here, we use 3D thermo-mechanical simulations to investigate the topographic response of a strength-varying hinterland basin imbedded in an orogenic plateau under the horizontal compression condition. Our results show that a strong hinterland basin experiences little deformation and develops into a lowland with respect to the surrounding plateau at the early stages of the collision. The lowland gradually shrinks and survives in the interior of the plateau for ∼30–40 Myr before merging into the plateau. In contrast, a weak hinterland basin uplifts soon after the initial collision and develops into a highland after ∼20 Myr of convergence. Topographic analysis reveals that the strong hinterland basin experiences an evident elevation drop after ∼20–30 Myr of convergence, followed by a rapid uplift. After compiling the paleoelevation data, we proposed that the Tibetan Plateau experienced a four-stage surface uplift, which was characterized by 1) the Gangdese and central watershed highlands isolating three lowlands during the Eocene, 2) the central lowland experiencing an elevation drop of ∼2000 m during the Oligocene, 3) the central lowland suffering a rapid uplift and merging into the Tibetan Plateau in the Early Miocene, and 4) the south and north lowlands rising and developing into a plateau similar to the modern Tibetan Plateau since the Middle Miocene.
Study on the Calculation Method of Active Earth Pressure and Critical Width for Finite Soil Behind the Retaining Wall
Authors: Huang Kan , Liu Runing , Sun Yiwei , Li Linyi , Xie Yipeng , Peng Xuejun
Published: May 2022

The method to determine the active earth pressure and critical width for finite soil behind the retaining wall in mountainous areas is one of the concerns of geotechnical engineering. In order to study the active earth pressure distribution of the finite soil against the retaining wall and determine the critical width of the boundary between the finite soil and the semi-infinite soil, this study focuses on investigating a retaining wall with finite cohesionless backfill. The shape of the failure surface is assumed to be a cycloid passing through the heel of the wall in the limit equilibrium state. Considering the deflection of soil principal stress induced by wall–soil friction effect, a calculation method of active earth pressure for finite soil is proposed by using an arc-shaped small principal stress trajectory, and the rationality of this method is verified. On this basis, a calculation formula of the critical width for finite soil is proposed. The influence of the internal friction angle and the wall–soil friction angle on the critical width of finite soil is examined. The results indicate that the active earth pressure of finite soil presents a nonlinear drum distribution along the height of the retaining wall under the failure mode of the cycloidal surface. The maximum value of active earth pressure is close to the bottom of the wall. The critical width of finite soil decreases with the increase of the internal friction angle, and its variation rate decreases gradually. The critical width of finite soil increases with the increase of the wall–soil friction angle, and its variation rate also increases gradually. Under different internal friction angles and wall–soil friction angles, the critical width values of finite soil calculated by the assumption of the cycloidal failure surface are smaller than those calculated by the Coulomb earth pressure calculation method.