bluuebunny/crossref_metadata_2025 huggingface dataset:
DOSE RELATIONSHIP DURING RADIOABLATION OF THYROID RESIDUAL IN PATIENTS WITH THYROID DIFFERENTIATED CANCER
Authors:   National Institute of Cancer of the Ministry of Health of Ukraine, Dzhuzha D. О.
Published: December 2022

Objective: to study relationship between the focal adsorbed doses (FAD) in the residual thyroid tissue (RTT) at radioiodine therapy (RIT) in patients with differentiated thyroid cancer (DTC) and efficacy of radioablation (RA). Materials and methods. FAD in RTT in 221 patients aged 25–74 years were analyzed. Scintigraphic investigations were executed using gamma-camera «МВ 9200» and single photon emission tomograph «Е. САМ 180». FAD in RTT were determined according to recommendation of the Committee on Medical Internal Radiation Dose. Results. Mean FAD in RTT was consisted (125.9 ± 8.6) Gy with range 1.8–1373.4 Gy. Positive effect after first course of RIT was in 77.4 % of patients complete RA of 78 % of RTT was achieved. Mean FAD in cases with complete RA was (147.0 ± 13.3) Gy with range 1.8–1373.4 Gy. Efficacy of RIT constantly increased from 68.2 to 93.7 % with increasing mean FAD from 30 to 370 Gy. Feather enlarging of FAD did not lead to any significant increasing of efficacy of RIT: enlarging mean FAD from 370 to 776 Gy increased efficacy of RA on 0.4 % only. Repeated RIT decreased FAD in RTT after each course. Using regression analysis was established type of relationship between efficacy of RA and FAD in RTT, according it efficacy of first RA consists at 40 Gy 72.8 %, 150 Gy – 84.9 %, 300 Gy – 91.2 %, 400 Gy – 93.7 %, 500 Gy – 95.7 %. Conclusions. FAD in RTT at RIT differ in large range, it can be explained different anatomical and functional condition of iodine accumulate thyroid tissue after surgical treatment and its radioresistance. Efficacy of RA increases with enlarging of FAD, this relationship is nonlinear. Efficacy of RA has the upper dose threshold in range 350–400 Gy. The frequency of thyroid tissue with high radioresistance is approximately 6 %. Key words: differentiated thyroid cancer, thyroid residual tissue, radioiodine therapy, radioablation, focal adsorbed dose, iodine-131.
RADIATION-INDUCED DAMAGE TO THE CARDIOVASCULAR SYSTEM AFTER RADIATION THERAPY IN WOMEN WITH BREAST CANCER
Authors:   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Bazyka D. A. , Lytvynenko O. O. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Demianov V. O. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine»
Published: December 2022

Despite current research in the development of drug-based cytostatic and targeted therapies in the treatment of breast cancer, radiation therapy (RT) is an important component in the treatment of this pathology in the postoperative period. At the same time, an important problem is the development of pathological changes in the heart in the long-term period, which worsen the quality of life and increase the risk of cardiac death 10 or more years after RT The problem of heart damage due to RT is gaining new significance due to the existing increase in the number of cancer patients requiring radiation exposure in the modern world. RT of malignant tumors of the breast and organs of the chest cavity causes damage to all structures of the heart, including the coronary arteries, valves, conducting system, pericardium. The frequency of heart damage increases in proportion to the time that has passed after RT. According to some authors, the prevalence of clinically significant radiation-induced heart diseases 5–10 years after RT is 10–30 %, and the frequency of asymptomatic lesions is 88 %. The duration of the latent period can reach 15–20 years. The work has an analysis of long-term studies of the presence of pathological changes that are found in the heart tissues of patients with breast cancer, as a result of radiation therapy. Key words: breast cancer, radiation therapy, adjuvant radiation therapy, radiation damage to the heart.
CLASSIFICATION OF MEDICAL EQUIPMENT FOR ANTI-RADIATION PROTECTION
Authors:   State Institution :National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Bazyka D. A. , Lytvynenko O. O. ,   State Institution :National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Lytvynenko O. O. ,   National Institute of Cancer of the Ministry of Health of Ukraine
Published: December 2022

Any collection of objects of study needs some arrangement, i. e. classification. The existing numerous classifications of anti-radiation agents are built on the basis of their anti-radiation effects of an integrated or differentiated nature. The work presents the chronology of the main classifications of chemical compounds that are able to protect against the short-term and long-term effects of ionizing radiation when they are introduced into the body both before and after exposure. The change of views, trends and paradigms regarding radioprotective compounds is shown. These classifications of anti-radiation medicines include radioprotectors, means of stimulating the radioresistance of the body, means of prevention and suppression of the primary reaction to irradiation, means of prevention and treatment of lesions from exposure to incorporated radionuclides, means of treatment of acute bone marrow syndrome, means of treatment of local radiation lesions. It is shown that modern concepts of radiation protection are based on fundamentally different «points of application» of groups of radioprotective agents and depend on the stage of radiation damage. Key words: irradiation, radiation damage, anti-radiation drugs, classification, radioprotectors, radiomodifiers, adaptogens, radiomitigators, decorporation agents.
Veteriner hekimliğinde iletişim becerileri için Calgary-Cambridge Kılavuzlarının Türkçeye uyarlanması
Authors: ÜNSAL ADACA Aytaç
Published: December 2022

Veteriner hekimler için iletişim becerileri, en az klinik beceriler kadar önem taşımaktadır. Müfredata eklenecek iletişim becerileri dersleriyle öğrencilere bu becerilerin kazandırılabilmektedir. Uluslararası alanda tıp, hemşirelik, eczacılık ve veteriner hekimliğinde iletişim becerileri eğitimlerinde sıklıkla Calgary-Cambrigde Kılavuzlarından yararlanılmaktadır. Yapılan bu çalışma ile orijinali İngilizce olan bu kılavuzların Türkçeye uyarlanması ve gerek öğrencilerin gerekse veteriner hekimlerin bu kılavuzlarda yer alan bilgilere anadilde erişebilmesi hedeflenmiştir. Bu amaçla, orijinal kılavuzlar dört farklı kişi tarafından İngilizceden Türkçeye çevrilmiş, yedi farklı uzman tarafından dil bilgisi, anlaşılırlık, içerik açısından incelenmiş ve kültürel uyarlama yapılmıştır. Hazırlanan taslak, Ankara Üniversitesi Veteriner Fakültesinde 2021-2022 Eğitim Öğretim Yılında öğrenim gören ve tesadüfi örnekleme yoluyla seçilen 10 gönüllü intörn veteriner hekim tarafından değerlendirilmiş, ardından dilbilgisi ve semantik değerlendirme için son kontrol amacıyla bir dil bilimciye başvurulmuştur. Medikal tercüme editörü olarak görev yapan dil bilimci, taslağın Türkçeden İngilizceye geri çevirisini yaparak iki metnin uyumunu değerlendirmiştir. 7 ana başlık, 19 alt başlık, 73 maddeye ek olarak üç diyagramdan oluşan kılavuzlar “Veteriner Hekimliğinde İletişim Becerileri İçin Calgary-Cambridge Kılavuzları” başlığıyla Türkçeleştirilmiştir. Yapılan çalışma sonucunda ana dilde erişime açılan bu kılavuzların, hasta sahibi ile iletişim sürecinde yalnızca öğrenciler için değil, aynı zamanda klinisyenler için de faydalı olacağı düşünülmektedir. Dahası fakültelerin klinik bilimlerinde görev yapan akademisyenler bu kılavuzlardan yararlandıkları takdirde, öğrencilerin lisans müfredatına ek olarak gizli müfredat aracılığıyla da iletişim becerilerini geliştirebileceği ileri sürülebilir.
Suni tohumlamanın tarihsel gelişimi ve dönüm noktaları
Authors: HERDOĞAN Mine , MART Feyzanur , ÇAY Hasan Ali , KAHRAMAN Durmuş , İNANÇ Muhammed Enes , GÜNGÖR Şükrü , ATA Ayhan
Published: December 2022

Suni tohumlama, tarihteki ilk reprodüktif biyoteknolojik uygulamadır. Günümüzde süt sığırcılığının gelişiminde üstlendiği rol ve insanlarda tüp bebek çalışmalarına öncülük etmesinden dolayı oldukça önemlidir. Yardımcı üreme teknikleri, cinsiyeti belirlenmiş sperma üretimi, çiftleşme ile bulaşan hastalıkların önüne geçilmesi, verim özellikleri yönünden üstün hayvanlar elde edilmesi ve dünyada büyük bir endüstriye dönüşmüş olan spermanın dondurularak saklanması ve satışı gibi birçok pratiğin ortaya çıkmasına yol açmıştır. Antonie van Leeuwenhoek’un spermatozoonu ilk kez mikroskop altında görüntülemesinden yaklaşık yüz yıl sonra, Lazzaro Spallanzani tarafından ilk kez bir köpekte gerçekleştirilen suni tohumlama uygulaması günümüze dek gelişimini sürdürmüştür. Canlıların kendine benzer özellikte bireyler meydana getirmesinde (Reprodüksiyon) önemli bir araç olan suni tohumlamanın, tarihsel süreci de merak uyandırıcı ve ilham vericidir. Bu derlemede, suni tohumlama ve ışığında gelişen biyoteknolojik uygulamaların tarihsel sürecine dair Türkçe ve yabancı kaynaklar incelenerek önemli dönüm noktalarına değinilmiştir.
Koyun ve keçi sütlerinde inek sütünün TaqMan Real-Time PCR ile tespit edilmesi
Authors: BİÇER Yusuf , SÖNMEZ Gonca , TURKAL Gamze , YILMAZ Tahir , ÇULHA Muhammed Hüdai , UÇAR Gürkan
Published: December 2022

Süt ve süt ürünleri içerdikleri yüksek besin değeriyle günlük diyetin önemli bir parçasını oluşturmaktadır. Ancak bu önemli özelliklerinin yanı sıra en fazla hile yapılan gıdalar arasında yer almaktadır. Koyun-keçi sütü ve ürünlerine inek sütünün karıştırılması süt ve süt ürünlerinde en sık karşılaşılan hilelerin başında gelmektedir. Bu durum, tüketiciler tarafından tercih edilmeyen sosyo-ekonomik potansiyel risklere neden olmaktadır. Bu çalışmada koyun ve keçi sütlerine farklı oranlarda karıştırılan inek sütü miktarının TaqMan Real-Time PCR ile tespit edilmesi amaçlanmıştır. Bu amaçla %1, %5, %10, %25, %75 ve %90 oranlarında keçi ve koyun sütlerine inek sütü karıştırılmıştır. Ayrıca saf inek sütünden elde edilen DNA sulandırılarak PCR işleminin duyarlılığı araştırılmıştır. Bu çalışmanın sonucunda, koyun ve keçi sütlerine karıştırılan %1 inek sütü ve 0,003 ng DNA varlığı tespit edilmiştir. Araştırma sonucunda TaqMan Real-Time PCR’ın koyun ve keçi sütlerine karıştırılan düşük düzeydeki inek sütünün tespit edilmesinde güvenilir ve hassas bir yöntem olarak kullanılabileceği düşünülmektedir.
CAUSES OF ANTISOCIAL BEHAVIOR OF ADOLESCENTS
Authors: Jevtic Bisera
Published: December 2022

Problems of antisocial behavior today are not only consequence of bad material conditions, nowadays they ensue more and more from contradictories of rich society that gave to everyone proportionally high standards in the area of work and behavior, but not in consumption field. This state brings us to the conclusion that today we live in structurally dissatisfied society, that is a base of many antisocial behavior problems. To prevent successfully antisocial behavior, it is necessary to research a wide field of disorders in social behavior of adolescents, from their most common forms, causes, to the consequences which this kind of behavior has on an individual and its social environment. The causes of escalated juvenile delinquency are found even in the school system, economic instability, bad influence of peers and also in neglect or excessive care of parents. In this paper, the author is focused on the most dominant causes of social behavior disorders. Target group are adolescents in high school, just because in this life period young people tend to absorb different forms of socially unacceptable behavior depending on the sex of adolescent. The paper gives a few topics for new researches.
Key words: adolescence, antisocial aggressive behavior, delinquency, deviant subculture and counterculture, dissocial behavior.
Implementation of the 2013 Curriculum at MTs AL-Abraar
Authors: Neliwati  , Devi Indah Sari
Published: December 2022

This study aims to analyse the Implementation of the 2013 Curriculum at Mts Al-Abraar. The purpose of this study is to find out how the effectiveness of the 2013 curriculum is compared to the previous curriculum, the constraints or obstacles occurred during the implementation of the 2013 curriculum, the respond of educators and students when using the 2013 curriculum which is far different from the previous curriculum, the things prepared in using the 2013 curriculum and the benefits or advantages for students and also educators when using the 2013 curriculum. This study uses qualitative methods because researchers consider the problems studied to be quite complex and dynamic so that the data obtained from the informants is captured using a more natural method, namely direct interviews with the informants so that natural answers are obtained. The conclusion that the researchers got from this mini research or observation is that schools have implemented the 2013 curriculum, but have not been able to achieve maximum implementation of the 2013 curriculum, because sometimes in learning they still use the KTSP system, such as teachers are more active than students, more teachers speak from on students. And this can happen because one of them is inadequate school facilities because in order to achieve successful implementation of the 2013 curriculum, adequate school facilities are also needed, such as infocus and others.
Features of Dermatosis in Professional Athletes (Literature Review)
Authors:   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Lipova E.V. , Sokolskaya A.A. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Vitvitskaya Yu.G. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Glazko I.I. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Silyutina T.A. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Published: December 2022

Professional athletes are regularly exposed to various influences of external factors, and their organs and systems function in the zone of absolute physiological and psychological limits. This affects the body as a whole. Various changes also occur on the skin, for example, a combined change in the qualitative and quantitative composition of opportunistic microorganisms inhabiting the skin, and a change in the water-lipid balance due to exposure to intense physical activity and various exogenous factors is predisposing to the development of various skin disorders. The presence of skin disorders in people professionally involved in sports not only reduces the quality of life, but also negatively affects the achievement of high sports results, the interdisciplinary interaction of doctors of various specialties, aimed primarily at the prevention of skin disorders in athletes, as well as their timely detection and the appointment of adequate treatment is essential.
Retinal Vein Occlusions Treatment Approaches: Review
Authors:   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Kurysheva N.I. , Sergushev S.G. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Pererva O.A. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Published: December 2022

Retinal vein occlusion (RVO) is the second among acquired vascular eye diseases, giving priority only to diabetic retinopathy. The severity of retinopathy depends on the location of the occlusion and the development of collateral vessels. RVO is not accompanied only by a decrease in visual acuity (VA), but also by the development of such complications as recurrent intravitreal hemorrhages, traction retinal detachment, secondary neovascular glaucoma. It causes the disability of patients and loss of professional fitness in people of working age. The treatment of RVO focuses on two main goals. The first one is the identification of risk factors and their drug therapy, and the second one is the identification and treatment of complications of retinal vein occlusion. The treatment of any pathology depends on early diagnosis, as well as a quick and well-chosen algorithm for managing the patient. The macular edema is treated by intravitreal injections of corticosteroids, antiVEGF, laser photocoagulation of the retina. Intraocular injections is currently the only way to provide a high intravitreal and intraretinal concentration of the drug. This review describes an algorithm for choosing the optimal treatment for RVO.
Personalized approach to ovarian stimulation in patients with paradoxical response in IVF programs
Authors:   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Ostrina S.Ya. ,   Moscow regional Perinatal Center, Russia, Moscow region, Balashikha., Serova O.F. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia,   Moscow regional Perinatal Center, Russia, Moscow region, Balashikha., Rudakova E.B. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia,   Moscow regional Perinatal Center, Russia, Moscow region, Balashikha., Fedorova E.A. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Published: December 2022

Presented are current data on the need to identify the main groups of patients in in vitro fertilization programs that require a personalized protocol for ovarian stimulation and modification of traditional ovarian stimulation protocols in in vitro fertilization programs. The influence of polymorphism of gonadotropin receptor genes on the ovarian response during superovulation induction was shown.
Accessory Mitral Valve Tissue in the Internist’s Practice
Authors:   Burnasyan State Research Center – Federal Medical Biophysical Center of Federal Medical Biological Agency, Posokhov I.N.
Published: December 2022

Attention to the topic of accessory mitral valve tissue intense in the 90s. After that, it would seem that interest began to fade, however, at present it has begun to increase again according the number of reviews found in MedLine. ‘What is the reason for the increased interest’, ‘what is the current state of art’ these questions were the background for this review. This lecture summarizes new knowledge about mitral valve accessory tissue and makes it clear that it is important to physicians in many specialties including internists.
Methods and Priciples of Building Complete and Consistent Knowledge Bases in the Differential Diagnosis of two Diseases Similar in Symptoms
Authors:   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia, Bolotov A.A. , Barchukov V.G. ,   A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Published: December 2022

Subject, topic, purpose. The article discusses methods, principles and approaches to the construction of complete and consistent expert knowledge bases in differential classification problems based on psychologically correct ways of obtaining information from an expert. Methodology. The problems of transferring knowledge from an expert to a computer program are considered. The most important characteristics of the knowledge extraction procedure are its psychological correctness, the completeness of the extraction and presentation of knowledge, as well as the consistency (infallibility) of the knowledge base. Since the main source of information is a person, in order to comply with this rule, the use of his logic of thinking must be a prerequisite. Results of the work. Rational methods and algorithms for the formation of large knowledge bases for the differential diagnosis of two diseases similar in symptoms are proposed on the basis of a psychologically correct method of interviewing an expert who solves the usual diagnostic task for him by a complete description of the case in text form. The results of Monte Carlo statistical modeling of the process of extracting expert knowledge for such tasks are presented within the framework of an algorithm based on the search for boundaries separating two diseases according to the binary approximation scheme from the so-called average object having half of the signs most characteristic of one disease and half of the signs most characteristic of another disease with a different number of used signs and three types of possible boundaries between diseases. Scope of application of the results. The results of the work are of applied importance for the construction of automated workplaces of practitioners in order to improve the quality of diagnostic conclusions and optimize the treatment of patients. Conclusions. Psychologically correct principles of knowledge extraction, methods and algorithms described in the article allow you to quickly and reliably build complete and consistent knowledge bases of large volume in various areas of differential diagnosis of diseases to create appropriate automated doctor’s workplaces, which will improve the quality of medical decisions, especially in difficult cases.
Genetic Diversity and Relationships Among Medicinal Species of Malva L. (Malvaceae) Based on Issr Markers
Authors: Ghafoor Bakhtiar Saadey , Hamarashid Sahar Hussein
Published: December 2022

The genus Malva L., popularly known as mallow, grows spontaneously in almost all of Europe and the Mediterranean region. This genus is morphologically very diverse and its species are used in the treatment of respiratory, urinary, and digestive problems, but some species are hardly distinguishable based on morphological features. We, therefore, performed a molecular data analysis for this genus. Amplification of genomic DNA of 90 randomly selected samples of six species of Malva using 5 primers produced 83 bands, of which 77 were found to be polymorphic (90.99%). The high average PIC and MI values revealed the high capacity of ISSR primers to detect polymorphic loci among Malva species. The genetic similarities of the six collections were estimated from 0.73 to 0.90. ISSR analysis revealed that Malva parviflora and M. vericillata had the lowest similarity whereas, M. neglecta and M. sylvestris had the highest similarity.
Bangladesh J. Plant Taxon. 29(2): 193-202, 2022 (December)
Struchium Sparganophorum (L.) Kuntze (Asteraceae): A New Angiosperm Record for the Flora of Bangladesh
Authors: Uddin Md Salah , Uddin Shaikh Bokhtear
Published: December 2022

Abstract not available
Bangladesh J. Plant Taxon. 29(2): 431-435, 2022 (December)
Relationship between serum ferritin and parathyroid function in adult male patients with transfusion dependent thalassemia
Authors: Urmi SFH , Munira Fatema Tuz , Begum Shelina
Published: December 2022

Background: Thalassemia is a genetic disorder of defective hemoglobin synthesis. In transfusion dependent thalassemia (TDT), iron overload is caused by repeated blood transfusion for a long time. This increased iron is deposited in body tissue and may lead to endocrine dysfunction.
Objective: To evaluate the relationship between serum ferritin and parathyroid dysfunction in adult male patients with TDT.
Methods: It was a cross sectional study which was conducted from March 2018 to February 2019 in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. For this study, 35 TDT male patients aged 18 to 40 year, were considered as study group and 35 age and sex matched apparently healthy subjects were considered as control group. The outpatient department of Hematology and Transfusion Medicine was the point of collection of study group. Parathyroid function was assessed by plasma intact para thyroid hormone (iPTH), serum total calcium and serum inorganic phosphate. Plasma iPTH and serum ferritin levels were estimated by Electrochemiluminescence Immunoassay method using automated analyzer. Serum total calcium and serum inorganic phosphate levels were estimated by colorimetric method using automated analyzer. Independent sample t test and Pearson’s correlation coefficient (r) test were applied for statistical analysis using SPSS version 16.
Results: In this study, serum ferritin level was significantly (p <0.001) higher in patients with TDT than that of healthy control. Correlation analysis showed negative correlation of serum ferritin with plasma iPTH and serum corrected calcium and positive correlation with serum inorganic phosphate in patients with TDT. Among them correlation with serum corrected calcium and inorganic phosphate were statistically significant (p <0.05).
Conclusion: This study concluded that TDT may be associated with elevated iron status which is inversely related with parathyroid function.
J Bangladesh Soc Physiol. 2022, June; 17(1): 1-5
Myocardial salvaging effect of turmeric (Curcuma longa) on experimentally induced myocardial injury in rats
Authors: Nahar Sharmin , Akhter Qazi Shamima , Yeasmin Nahid , Fatema Farhana
Published: December 2022

Background: In Ayurveda turmeric (Curcuma longa) has been used for cardioprotection. Experimentally induced myocardial injury is clinically similar to human myocardial infarction.
Objective: The study was designed to assess the myocardial salvagingeffect of turmeric (Curcuma longa) on experimentally induced myocardial injury in rats.
Methods: This experimental study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during 2015. Total twenty eight (28) Wistar albino male rats (aged 13±1 weeks; 125±25 gm) were randomly grouped into NS (normal control group), ISO (isoproterenol treated control group),Tm+ISO (turmeric pretreated and isoproterenol treated group) and Am+ISO (amlodipine pretreated and isoproterenol treated group). All the rats were sacrificed on 10th day of experimentation. . Blood samples were collected. Serum carduac troponin I (cTnI) level was estimated by AxSYM methodand serum malondialdehyde (MDA) level was estimated byspectrophotometric method.For statistical analysis, one way ANOVA followed by Bonferroni post hoc test was done by using SPSS 22.0 version.
Results: The mean serum cTnI and MDA level was significantly (P<0.001) higher in ISO in comparison to all other rats of different groups. Whereas, the mean serum cTnI level was lower in Tm+ISO and Am+ISO in comparison to that of ISO which were statistically significant (P<0.05). Again, mean serum MDA level was significantly lower in Tm+ISO(P<0.05) and Am+ISO(P<0.001) in comparison to that of ISO.However, there were no significant differences between Tm+ISO and Am+ISO.
Conclusion: The results of the study concluded that turmeric has myocardial salvaging effect on experimentally induced myocardial injury inrats.
J Bangladesh Soc Physiol. 2022, June; 17(1): 34-40
Model for estimating the impact of healthcare costs in non-hospitalized Covid-19 patients treated with remdesivir
Authors: Ruggeri Matteo , Signorini Alessandro , Caravaggio Silvia , Falcone Marco , Di Perri Giovanni
Published: December 2022

Objectives: In March 2020, the COVID-19 pandemic outbreak caused significant negative changes worldwide. Important investments were suddenly needed in the economic, social, and healthcare fields. This analysis sets out to show the economic impact of the administration of remdesivir in ambulatory patients, who are affected by Covid-19, at high risk for severe progression, and eligible for the antiviral treatment.
Methods: The budget impact analysis is based on the assumptions already presented in a study published in 2020 by the same Authors. The analysis was updated with a new simulation of the pandemic curve which included the vaccination plan. Data were collected from official Italian sources and from the academic literature. The Italian National Health Service (NHS) perspective was used in the analysis. Remdesivir treatment was compared in terms of economic costs with the Standard of Care over a period of 20 weeks. Such timeframe was chosen because of the uncertainty of the pandemic evolution and considering that this is the time of a complete pandemic curve. A comparison with other therapeutic solutions was not performed in this analysis as the relative costs were not available at the time of the study.
Results: The model estimates that, in 20 weeks, 8,002,015 subjects are infected by Covid-19, with a 0.8% hospitalization rate. Among hospitalized patients, 19.6% could be eligible for remdesivir treatment, for a total number of 3,619 patients, with a 12% market share.
Conclusion: The analysis shows that remdesivir therapy is dominant and its use could determine a reduction in hospitalizations and transfers to intensive care units compared to the Standard of Care, with a potential saving of € 50.8 million and a decrease of the number of Covid-19-related deaths between 600 and 1,100.
Armenian Higher Education Perspectives On Internationalisation
Authors: Soghomonyan Zaruhi
Published: December 2022

As truly mentions Knight (1999), given the rising interest in and understanding of “…international dimension of higher education…”, the usage of the term “internationalisation” is becoming more frequent. She underscores (Knight, 1999) two possible reasons for the aforesaid phenomenon: first, internationalization is becoming more crucial for higher education providers, yet second, she posits that this can be accounted for by the fact that the term internationalization is perceived differently by different people, thus giving rise to this plethora of interpretations. Even two decades following what Knight termed as “crucial” for higher education, we can still trace “globalization” and “internationalization” as being increasingly popular terms when studying contemporary writings on higher education (Tight, 2019). Judging from a wide range of up-to-date research and literature on internationalization of higher education, it can be inferred that the confusion and interchangeable use of the terms is still a reality all over the world, and Armenia is no exception. Given the ongoing debates on the terms and the scope each of them encompasses, the paper draws on international and Armenian literature and official documents to critically assess whether the term “internationalization” is perceived the same way across Armenian HEIs, and whether RA institutions have a set model for internationalization to compare their operations against. The research outcome will be principally important as it will provide insights into the generic picture of internationalization in general and the way it is seen by Armenian HEIs, and will provide fertile ground for building up further studies on the issue.
The Perception Of Emirati Students Towards Academic Advising In Higher Education: A Case Study Of Abu Dhabi Polytechnic
Authors: Abu Shunnar Bashar
Published: December 2022

Academic advising is a critical element of the university system that can help students solve their academic problems and succeed in their academic and professional careers. This study aims at investigating students’ perception of academic advising at ADpoly programs. It employs the descriptive and analytical approach for collecting data from a sample of (364) students (males and females) from all academic years. The results of online surveys conducted in the first semester of the academic year 2022-2023 show that, overall, the respondents were positive about academic advising services. The newer students tended to be more satisfied with academic advising than the older students. Also, the results indicated no statistically significant differences between students related to their gender.  Finally, the study provides recommendations and future work related to the studied topic.
Virtual Reality in education: Attempting an epistemic justification
Authors: Stelios Spyridon , Tzavaras Panagiotis , Dermata Mona
Published: December 2022

In discussing the limits of human knowledge, physical objects are, in principle, not identical to the apparent ones. This is because the latter depend also on the observer. Virtual reality (VR) models are environments that address the senses and therefore belong to the apparent space. Therefore, they seem to prevent an epistemic justification. Based on that, this paper discusses VR technology’s potential to provide knowledge of external reality to students. This is particularly important in light of the conditions imposed by the COVID-19 pandemic, which have led to an increasingly significant role of VR related technologies in education. The research question of this study is whether VR models being used as educational tools, bring us closer – or not – to knowing the properties of physical objects. The main focus of this epistemic investigation is Russell’s theory of perception with an emphasis to the concept of space. Analysis indicates that VR is educationally useful especially when it comes to objects that are absent from our perceptual range. VR technology brings us closer to the theoretical properties of non-perceptual objects, those that cannot be perceived by the senses, like exoplanets. Furthermore, it brings us closer to the non-perceptual properties of directly perceived objects, properties referring, for example to subatomic structures. In a theoretical level, this macro and micro “terra incognita” may be linked to the sensibilia entities proposed by Russell (1914).
On Asian Transnational Adoptees’ Self-Determination for Cultural Identification: An Analysis of Greg Leitich Smith’s Novel, Ninjas, Piranhas, and Galileo
Authors: Want Kaori Mori
Published: December 2022

Transnational adoption from Asian countries to the US started in the 1950s. When Asian transnational adoptees first came to the US, they were encouraged to assimilate into white American cultures because many were adopted by white Americans, yet due to the spread of the ideal of incorporating adoptees’ ethnic background in parenting for the adoptees’ healthy identity development in the US, white parents have started encouraging their adopted children to know their Asian cultural roots. While white parents are trying to give their adopted children either American culture or Asian culture, what do Asian adoptees feel about their cultural identification? Isn’t it Asian adoptees themselves who need to decide their cultural identification? This article examines these questions by reading Greg Leitich Smith’s Ninjas, Piranhas, and Galileo from interdisciplinary perspectives. Combining the literary texts and the findings of adoption research in the fields of anthropology, sociology, and psychology, this article concludes that while white adoptive parents need to provide cultural experiences of their adopted children’s birth culture to their children, it is Asian transnational adoptees themselves who have the right to decide their cultural identification.
Psychological Wellbeing: Toward an Innovative Provision of Mental Health and Wellbeing in the United Arab Emirates
Authors: Alrumaithi Fatema , Moonesar Immanuel A
Published: December 2022

While physical health strategies have been developed through establishing healthcare centers and e-services, psychological health services have not improved by the same degree, especially in the UAE. Since the ongoing COVID-19 pandemic was declared a public health emergency in January 2020, the demand for health services—including mental healthcare—has increased and led to the detection of several global gaps within the healthcare systems. Thus, it is essential to understand the requirements of advanced technologies and approaches to provide healthcare services. Nevertheless, social cohesion, financial burden, and associated stigma are among the primary factors behind the reluctance to approach psychological wellbeing services. Consequently, this study aims to explore how innovation can support the provision of mental health services and how it can assist in spreading awareness of psychological wellbeing and reduce the associated stigma, in the context of the UAE. A qualitative research design was afollowed, that focuses on the preliminary literature review of innovative methods applied in the area of mental health and psychological wellbeing services. Additionally, primary data was collected by conducting a focus group discussion among specialized counselors, psychologists, and other related professionals working in the city of Abu Dhabi. The acquired data were analyzed based on the research objective with NVivo Software (QSR 2.0). The fidings were evaluated to present results that answered the research questions. The coding process led to finalizing six unified codes that were extracted into six correlated themes: Workplace environment, Counseling sessions, School children matters, COVID-19 pandemic concerns, Treatment mode, and Future mental health development. Also, visual illustration was generated and presented. The findings of this research provided recommendations for a strategic framework and suggestions for future research.
Conversation Codes in Selected Nigerian TV Health Talks
Authors: Oladipo Abiola Mary , Amoniyan Oluwasegun , OLEKANMA Nkpuruoma Joy
Published: December 2022

A conversation entails the exchange of thoughts, ideas, emotions and questions between two or more individuals for a purpose. Conversation in the 21st century may be physical or blended. Studies have investigated discourse in friendship, negotiations, classroom and literary texts for interpretations, but little attention has been paid to the health talk in the recent time in Nigeria despite its significance in the post-Covid era. Few available linguistic analyses concentrated on doctor-patient interaction with less attention to those who are healthy at the moment but may need precautions to remain hearty. The laxness in a linguistic study on health will continue to create a gulf between health and linguistic analysis. Linguists need to engage in health jargon for proper exposition and linguistic simplification. Therefore, this research aims to analyze conversational codes in selected Channels TV health talks in Nigeria. With the application of the conversational codes by Harvey Sacks. Qualitative analysis is employed to interpret conversational codes in the data selected for the study. Out of the different episodes on Channels TV daily, five episodes on hypertension, COVID-19, heart attack, diabetes and sickle cell disorder constitute the data. The study explores the theory of conversation analysis by Harvey Sacks. The approach investigates communication systems and how discourse is constructed toward achieving the ultimate goal of interaction among discussants with minute overlaps. The study qualitatively examines turn-taking, adjacency pair, sequence, repair, opening and closing. Insight from Sacks' approach reveals that turn-taking is frequently used in the episodes with varying percentages (35-40%). Turns are flexible, and they could be determined by the host or the guests depending on the background exposure of the host to health matters. The use of fillers varies from speaker to speaker with percentages. Socio-cultural roles affect turn construction management. The hosts often ask more questions than the guest, depending on the information the guest supplies, which determines follow-up questions. Theoretically, this study can support the theory of conversational analysis- of conversational codes. The study can be a reference for applied linguistics research insights to account for telephone calls, political interviews, classrooms and debates.
Lipohypertrophy prevalence and its associated risk factors in insulin-treated patients with type 2 diabetes in North Borneo, Malaysia
Authors: Nain Rose A , Thomas Deena Clare
Published: December 2022

Background: Insulin-treated diabetes patients are at high risk of developing lipohypertrophy, which can negatively impact treatment outcomes. Early detection of lipohypertrophy is crucial to preventing blood glucose fluctuation. Unfortunately, this clinical issue is often overlooked by nurses, causing the development of vascular complications, which leads to an increase in the morbidity and mortality of the type 2 diabetes mellitus population.
Objective: This study was conducted to identify lipohypertrophy prevalence and to establish the association between the presence of lipohypertrophy and its associated risk factors, including years on injection, total injection in a day, total insulin unit per day, often change needle, insulin injection site and move to a different area.
Methods: This cross-sectional study included 128 patients with type 2 diabetes mellitus who received insulin therapy in an outpatient diabetic clinic. Questionnaires on socio-demographic and lipohypertrophy-associated risk factors were distributed among patients, and lipohypertrophy-assessment was done using a checklist. Descriptive statistics and Pearson Chi-square were used for statistical analysis.
Results: The prevalence of lipohypertrophy was 51.6% (95% CI: 42.6, 60.5). Swelling on fatty tissue (46.1%) exhibited the highest percentage of lipohypertrophy features during the assessment. Pearson Chi-Square revealed a significant relationship between the presence of LH and BMI categories (χ2 = 10.059, df = 3, p = 0.018), duration of injection (χ2 = 15.001, df = 3, p = 0.002), frequency of needle replacement (χ2 = 9.525, df = 3, p = 0.023) and rotation of injection site (χ2 = 5.914, df = 1, p = 0.015).
Conclusion: The high prevalence of lipohypertrophy indicates a need for a prevention strategy. Thus, nurses should play an important role in educating patients regarding the proper administration of insulin injections and performing a routine lipohypertrophy assessment and health education on the correct method of insulin injection.
Clinical profile, treatment, and outcomes of patients with COVID-19 in a tertiary referral hospital in South Sumatera, Indonesia: A retrospective single-center study
Authors: Marteka Deli , Malik Amarila , Faustine Ingrid , Syafhan Nadia Farhanah
Published: December 2022

Background: Although there are fewer COVID-19 cases in Indonesia, the pandemic is still ongoing. COVID-19 has a significant death rate in Indonesia, but lack of information on the effect of different clinical and demographic factors on COVID-19-related grimness and mortality in Indonesia.
Objective: This study examined the clinical profile, treatment, and outcomes of patients with COVID-19 at Lahat Regency Hospital in South Sumatera, Indonesia, to find relevant markers that might be utilized to predict the prognosis of these patients.
Methods: This was a retrospective single-center study of all medical record files of confirmed patients with COVID-19 admitted to Lahat Hospital from September 2020 to August 2021 (n = 285). Descriptive statistics, Chi-square, Mann-Whitney, Multiple Logistic Regression, and Cox's proportional hazards model were used for data analyses.
Results: This study included 65 non-hospitalized and 220 hospitalized patients. Hospitalized patients were divided into dead and alive groups. The median age was lower in the non-hospitalized group without gender discrimination, and most hospitalized patients had comorbidities. Vital signs and clinical features were significantly different in hospitalized patients compared to non-hospitalized. The survival patients in the hospitalized group showed lower white blood cell (WBC), neutrophil percentages, and neutrophil-lymphocyte ratio (NLR) but higher lymphocyte and eosinophil. Non-survival patients had elevated alanine aminotransferase (ALT), blood urea nitrogen (BUN), creatinine, blood glucose, and potassium. The use of Favipiravir and Remdesivir was significant between the alive and dead groups. The mean hospital stay for all patients was 9.49 ± 4.77 days, while the median duration of hospital time was 10.73 ± 4.33 days in the survival group and 5.39 ± 3.78 days in the non-survival group. Multiple logistic regression analysis determined respiration rate, WBC, and BUN as predictors of survival.
Conclusions: Age and comorbidities are significant elements impacting the seriousness of COVID-19. Abnormal signs in laboratory markers can be used as early warning and prognostic signs to prevent severity and death. Potential biomarkers at various degrees in patients with COVID-19 may also aid healthcare professionals in providing precision medicine and nursing.
Convivencia escolar. Dimensión y evolución
Authors: Flores Suárez Alejandro , Herrera Beltrán Isabel
Published: December 2022

El artículo presenta la dimensión y evolución conceptual de la convivencia escolar; así mismo, aborda la dimensión de la competencia social como elemento destacado en el proceso de evolución social del individuo; de este modo, se pretende demostrar que la metodología de aprendizaje cooperativo, en el entorno educativo, promueve mejoras sustanciales en el marco de la convivencia y el desarrollo de habilidades sociales desde la dimensión personal del alumnado.
Álvaro Cepeda Samudio: una vocación literaria diferente
Authors: Saldarriaga Berrio Vanesa
Published: December 2022

Presentación:

El semillero Escaletra había surgido como un grupo de interés en literatura, y terminó convirtiéndose en el semillero de investigación que estudiaba las relaciones entre el arte de las letras y el cine. Vanessa Saldarriaga Berrío no faltó nunca a una reunión. Era una veinteañera inusualmente alta, tenía un andar cansino que engañaba, porque era ágil, dinámica y participativa.

Aunque a Vanessa le apasionaba la obra de Edgar Allan Poe, y era lo que le hubiera querido estudiar, asumió con genuino interés el trabajo de investigación como auxiliar, estudiando a Álvaro Cepeda Samudio. Después de leer la obra del barranquillero, se sumergió en la lectura de artículos y tesis de grado, que produjo una reseña que ahora publicamos.

Vanessa nos dejó en diciembre de 2020, pero este corto ejercicio, por modesto que parezca, fue un estímulo que ayudó a fortalecer el compromiso del resto de los estudiantes que integraban el semillero por esos días. Su trabajo es el testimonio de la entrega y la vocación académica de uno de nuestros egresados, pero también parte de la huella que dejó en nosotros.

Como un homenaje, la revista Luciérnaga publica póstumamente este documento que, en su momento, sirvió como avance de investigación del semillero.
Derechos humanos, género y violencia desde la perspectiva de los Departamentos de Consejería Estudiantil
Authors: García Ayala Darwin Patricio , Gil Gesto Isabel , Íñiguez Ibarra Ana Lucía , León Machuca Walter Fabián
Published: December 2022

El proyecto “Derechos Humanos: Equidad Social y de Género, un camino hacia la Coeducación¨, ejecutado por la Carrera de Género y Desarrollo de la Universidad de Cuenca como proyecto de Vinculación con la Comunidad, pretende visualizar y evidenciar, desde la perspectiva de las y los actores educativos (docentes, padres y madres de familia, estudiantes, funcionarios y funcionarias de los departamentos de consejería estudiantil – DECE) aquellos aspectos relacionados con la violencia, enfoque de género y derechos humanos, cómo se sincretizan en la práctica y cotidianeidad dentro de los entornos educativos y cuáles son sus principales derroteros; por otro lado, este estudio pretende constatar los criterios e imaginarios que circundan alrededor de cómo se concibe al género y la violencia en dichos actores educativos para su posterior orientación y aclaración teórica. En esta ocasión el análisis se centra en aquellas personas que forman parte de los DECEs de las instituciones participantes en este proyecto, cuyo diagnóstico permitirá tomar acciones desde la academia a fin de implementar estrategias de acción que tomen en cuenta los grupos humanos, sus contextos y sus necesidades.
Radio infantil en Neiva: “Pompas de Jabón”, estrategia de educomunicación.
Authors: Forero Mosquera Óscar Iván , Garzón Obando Laura Milena , Montano Cardozo Tania Marcela
Published: December 2022

El propósito del presente documento es analizar la incidencia de la estrategia radial educomunicativa “Pompas de jabón”, en el mejoramiento de las competencias de lectoescritura en los niños de los grados 3, 4 y 5 de la Institución Educativa María Cristina Arango de Pastrana y el colegio El Rincón de la Expresión en Neiva, en el año 2021. La investigación se desarrolló con un enfoque mixto, que contempla componentes de tipo cuantitativo y cualitativo, siendo este último el abordaje destacado. Se revisaron prácticas docentes, se implementaron talleres dentro de los cuales estaba la radio, con estudiantes, orientados a las competencias de lectoescritura y se analizaron sus efectos a través de la observación. El trabajo permitió corroborar que es posible y viable fortalecer las habilidades de lectoescritura de los niños, por medio de una estrategia radial educomunicativa.