bluuebunny/crossref_metadata_2025 huggingface dataset:
Penyuluhan Pencegahan Penularan Penyakit dari Alat Selam (Mouthpiece) dan Tips Pemeliharan Kesehatan Gigi dan Mulut bagi Komunitas Penyelam "Corona Diving Club"
Authors: Priandini Dewi , Wirahadikusumah Andy , Arief Budiman Johan , Ariwibowo Taufiq
Published: July 2023

Diving Sports activities are very fun, because it is enjoyable. However, this sport is full of risks. If done carelessly, it will cause health problems including dental and oral health. The mouthpiece is the part that is attached to the SCUBA or snorkel equipment. In particular, the use of a mouthpiece has a negative impact on oral health, among other things, it can cause pain in the jaw (Temporomandibular Disorders), as well as transmission of diseases, name it bacteria, viruses or fungi. In 2020, the whole world, including Indonesia, was hit by a global pandemic in the form of Corona Virus Disease 19 (COVID-19) which has systematically changed human lifestyles. The Covid-19 pandemic is now gradually coming to an end. Therefore, it is necessary to carry out counseling and training regarding oral and dental health in the diver community during adaptation to new habits. Training and counseling will be carried out using online methods or distance learning using presentations on how to maintain dental and oral health in the Corona Diving Club diver community. Training and counseling were carried out for 20 community member cadres for 60 minutes, by giving presentations and followed by questions and answers. Increased knowledge about dental and oral health, measured by giving questionnaires before and after exposure to the material. The results are expected to increase the knowledge and abilities of the Indonesian cloth-loving community in Jakarta in maintaining oral health during the adaptation period to new habits during the Covid-19 pandemic. The outputs of this community service activity will be set forth in the form of HAKI PKM video recordings, leaflets and posters regarding dental and oral health care.
Penyuluhan Pentingnya Menjaga Kesehatan dan Merawat Kebersihan Gigi Tiruan di Panti Werdha Wisma Mulia
Authors: Yuliarsi Yayuk , Poedjiastoeti Wiwiek , Nugroho Santosa Didi , O. Iskandar Bernard , Dewi Ranggaini Monica
Published: July 2023

The impact of the Covid-19 has made the elderly's access to dental and oral health even more limited. Oral hygiene in the elderly living in nursing homes is often ignored so it falls into the poor category. The high prevalence of caries and other dental problems makes the elderly need more dental treatment. Poor oral health can lead into systemic or local infections that will affect general health, especially in the elderly who have impaired physiologic or pathologic function. Increased knowledge will improve their oral hygiene. Therefore, to increase members' knowledge and awareness to oral health, FKG Trisakti held an education to maintain their oral health and dentures. Pre and post tests are given to the participants to determine the success of the education. T test result showed increase in knowledge from participants before and after giving the material. Further training can be given to caregivers as they were there to help the elderly maintain their oral care.
LEADING MOTIVES OF THE EDUCATIONAL ACTIVITY OF FUTURE PHILOLOGY TEACHERS: DIAGNOSTIC ANALYSIS AND PROJECTION
Authors: PETRYSHYNA OLGA , HAPON LESYA , NAUMOVYCH YANA
Published: July 2023

Motivation of the future philology teachers to educational activity is an important part of students’ training at higher education institutions. The desire of applicants to acquire professional knowledge, to form skills and abilities that will form the basis of their pedagogical activities in the future, should become the main factor that encourages them to conscious study of the disciplines of general and professional training. The value-motivational aspect of philology students’ teaching involves creating a supportive environment at the institution to satisfy the interests and needs of students, taking into account their personal qualities, level of cognitive activity, readiness to realize themselves in society, understanding the importance of their future profession, etc.

In the conditions of Russian aggression, the problem of motivation of students’; educational activities is actualized, since the war affected not only the form of education and its organization, but also the attitude, personal motives, and approaches of the students to the future professional activity in the conditions of the war and in the post-war period. The purpose of the article is to determine and analyze the motives of the educational activities of philology students to study the disciplines of general and professional training in the conditions of martial law.

A survey of applicants of the first (bachelo’s) level of educational programs of the specialty 014.01 Secondary Education of the Faculty of Philology and Journalism of Ternopil Volodymyr Hnatiuk National Pedagogical University was conducted and analyzed to identify motivational typology. According to the results of the questionnaire, the leading motives of the educational activity of future philology teachers were determined and described, their prevalent personal and professional interests during the study of general and professional training the disciplines under martial law were highlighted.
TECHNOLOGIES OF COMPUTER GEOMETRIC MODELING AS A MEANS OF MOTIVATING FUTURE CIVIL ENGINEERS FOR PROJECT ACTIVITIES
Authors: BOIKO VLADYSLAV
Published: July 2023

Computer geometric modeling is a necessary component of the design process in modern engineering. This is a technological process that allows you to create virtual objects and systems using computer programs and specialized algorithms. Computer geometric modeling is used in many fields of engineering, including construction, mechanical engineering, aviation, medicine, and others. One of the main tasks that can be solved with the help of computer geometric modeling is the design of buildings and structures. Construction is one of the most complex and costly industries, where ensuring the safety and efficiency of projects is a particularly important task. Computer geometric modeling allows civil engineers to create and analyze virtual 3D models of buildings, which greatly facilitates the design process and increases the quality and efficiency of projects.

The purpose of this article is to study the importance of computer geometric modeling technologies for future civil engineers and their motivation for project activities.

The article is devoted to the study of the impact of computer geometric modeling technologies on the motivation of future civil engineers for project activities. The authors consider the advantages of using these technologies in the educational process and examine the practical experience of their application. The article contains an overview of previous research in this area, a description of the importance of using computer geometric modeling to motivate engineering students, and prospects for further research into computer geometric modeling technologies in the engineering field. As a result of the study, it was established that the use of computer geometric modeling technologies has a positive effect on the motivation of future civil engineers for project activities. In particular, students showed greater interest and involvement in the learning process, which allows them to acquire more knowledge and skills in this field. The article describes methods and means of computer geometric modeling, such as CAD, BIM, and others, and shows their advantages in comparison with traditional design methods. In addition, the article examines the impact of the use of computer geometric modeling technologies on improving the quality of design activities and the efficiency of production of building structures. The results of the study can be useful for teachers and students working in the field of engineering education, as well as for professionals involved in design and construction. In general, the article will help expand our knowledge about the application of computer geometric modeling technologies in the modern engineering field and increase interest in their use in project activities.
THE USE OF ARTIFICIAL INTELLIGENCE AND NEURAL NETWORKS IN THE EDUCATIONAL PROCESS IN PROFESSIONAL DISCIPLINES BY STUDENTS MAJORING IN PROFESSIONAL EDUCATION (DIGITAL TECHNOLOGIES)
Authors: SOMENKO DMYTRO , TRYFONOVA OLENA , SADOVYI MYKOLA
Published: July 2023

This article examines the possibilities and prospects of using artificial intelligence and neural networks in student education. The use of these technologies can have a positive impact on the quality of education and provide more effective knowledge transfer. The authors of the article explore the possibilities of using neural networks in the study of professional disciplines by students of the specialty «Vocational Education (Digital Technologies)». Among the advantages of using artificial intelligence and neural networks in education are the optimization of the learning process, adaptive and individualized learning, increased motivation, and automatic assessment of knowledge and skills. Additionally, the possibility of using neural networks for data analysis is considered, which will allow students to improve the quality of research and increase the accuracy of results. Moreover, artificial intelligence systems can help ensure more effective remote learning. Furthermore, artificial intelligence can be applied to create virtual simulators and trainers, allowing students to acquire practical skills and experience without risking experimentation on real objects. For instance, this can be useful for students who study computer repair and modernization, where practical experience and safe and efficient equipment handling are essential.

Despite the advantages of using these technologies, such as personalized learning and increased efficiency, potential drawbacks should also be considered. Possible drawbacks include low-quality source data, potential errors in the neural network's operation, and the possibility of ethical problems. To minimize the negative impact of these drawbacks, it is necessary to use technologies that consider their limitations and risks, as well as to constantly improve the technical base and increase the qualifications of teachers and students. Therefore, the use of artificial intelligence and neural networks in education is a promising and powerful tool that can improve the quality of education, make it more efficient and personalized, and provide students with the skills and knowledge they need to succeed in the digital age.
ELECTRONIC SUPPORT OF HIGHER EDUCATION SEEKERS IN THE PROCESS OF THEIR PRACTICAL TRAINING
Authors: POLHUN KATERYNA
Published: July 2023

In the era of digitalization of all social life spheres, especially educational environment, wide using of distance and blended learning technologies the process of students’ practical training at higher education institutions demands creating the system of electronic support. The article deals with the demonstration of changing practice paper reporting documents into their electronic analogues as well as it deals with the analysis of its consequences. Thus, a diary of psychological and pedagogical observations should be substituted with a blog. Drafts of lesson plans or upbringing events can be submitted in the form of PDF files, PPT presentations, online lesson records etc. In the research process, theoretical methods were used (analysis, comparison, generalization and systematization of information obtained during the study of scientific literature), as well as practical methods (a survey of students and teachers was conducted regarding the convenience, effectiveness and feasibility of practice electronic reporting). The research aims at proving the expediency of switching to practice electronic reporting and implementation of electronic support reasonability of students of higher education institutions in the period of their practical training. The study of the effectiveness and expediency of electronic support for the practical training of education acquires took place during four academic years. Survey results, including students and academic staff, have shown that moving to practice electronic reporting provides conditions for information to be submitted in different forms, creates opportunities for commenting blog notes, interchanging experience among students, setting dynamic students’ feedback. Using MOODLE system for educational process gives an opportunity to realize student’s activity due to individual educational approach as well as to provide an opportunity for group and collective interaction. A system of electronic courses was created in accordance with the specialties and types of practice of students according to the curricula. Ensuring the high-quality use of modern information technologies depends on the participants’ access to appropriate technical means and the Internet, as well as the level of their digital literacy.
CYBER SECURITY IN DECENTRALIZED WEB 3.0 INTERNET ECOSYSTEM
Authors: HEVKO HEVKO , YASHCHYK OLEKSANDR , SAVCHYN TETIANA , HILTAI LESIA
Published: July 2023

The article examines the problem of cyber security on the Internet; the main principles of improving the global culture of safe network interaction are clarified. Issues related to ensuring personal information security while using Internet systems are considered. Cyber security is an important issue in today’s world, and its protection requires an appropriate level of attention. The importance of knowledge about technologies and methods of protection against cyber threats for everyone who uses computer systems and the Internet is noted. The relevance of studying cyber security by students is considered. Because cyber threats can pose a serious threat to the security and privacy of personal information, it is important that students have knowledge of the basic technologies and techniques to protect themselves against cyber threats. Also, many students study digital technology and computer science, which makes knowledge about cyber security even more important. While students may study various aspects of cyber security as part of their degree program, it is important for them to develop general understanding of how to protect themselves and their computer systems from cyber threats.

The article describes how the study of social engineering will help students understand the tactics, techniques, and approaches used by attackers to obtain sensitive information. It is important that they understand the ways in which cyber security systems can be attacked and the methods that can be used to prevent such attacks. Web 3.0, technology is considered in detail as a new generation of the Internet, which involves a more decentralized and intelligent network, with more structured data and the ability for automated processing. The main components of Web 3.0 are described: blockchain, semantic web, artificial intelligence and decentralization. The importance of protecting personal information and security against misuse of information in the latest Internet ecosystems is indicated. With the development of Web 3.0, there are more and more questions about privacy and security on the Internet. The article examines the importance of developing effective protection methods and regulating the use of these technologies to ensure a safe and reliable Internet for users. Web 3.0 technology has great potential for the development of the Internet ecosystem, and will become the basis for new innovations and opportunities in various fields. However, it is necessary to ensure the protection of personal information and security against abuse in order to ensure the positive impact of these technologies on society.
Sistem Informasi Pengolahan Data Siswa di SMA Informatika Ciamis Menggunakan Microsoft Visual Basic
Authors: Rohayati Tuti , Sidiq Maulana , Dwicahya Supriatman Rian
Published: July 2023

In order to face the era of globalization, science and technology are developing rapidly, this must also be supported by qualified human resources (HR). With these quality human resources, an institution or company can make good use of technological advances, especially in the field of computers. In educational activities it is also necessary to have a computerized system for various purposes. especially in the management of student data. In SMA INFORMATIKA KABUPATEN CIAMIS, student data processing is still written directly into the main book because there is no application program that can process student data. To increase the efficiency and effectiveness of the authors make a simple application to facilitate jobs related to processing student data. Information system for processing student data will be made using Visual Basic programming and using Microsoft Access as the database. The results of this study are in the form of a student data processing information system that can help overcome problems in searching student data and student data reports.
Amicable Settlements: A Comment on Guideline 13(2)(v) of the Revised Guidelines for Consideration of Communications and Monitoring Implementation of Decisions by the African Committee of Experts on the Rights and Welfare of the Child
Authors: Nanima Robert Doya
Published: July 2023

The African Committee on the Rights and Welfare of the Child (African Children’s Committee) is mandated to monitor the implementation of the African Charter on the Rights and Welfare of the Child in Africa (African Children’s Charter). The African Children’s Committee has developed Revised Guidelines for Consideration of Communications and Monitoring Implementation of Decisions by the African Committee of Experts (RCG) which provide for amicable settlements. This contribution argues that the implementation of amicable settlements presents gaps that do not reconcile the substantive aspects on the one hand and the procedural on the other, in terms of practical implementation. This contribution contextualises the use of amicable settlements in international law and evaluates their use by the African Children’s Committee. The comment examines the application of Guideline 13(2)(v) and its consequential implications and it is proposed that it should be revisited to distinguish between the substantive and procedural aspects of the amicable settlements and how they should be handled to their logical conclusion.
The use of inoculant and micronutrients on soybean in the conditions of the Central Chernozem region
Authors:   TNIISKH – a branch of the I.V. Michurin Federal Research Center, Shabalkin A.V. , Dubinkina E.A. ,   TNIISKH – a branch of the I.V. Michurin Federal Research Center
Published: July 2023

The effect of soybean seeds inoculation as well as the treatment of seeds and vegetating soybean plants with microfertilizers on productivity and economically valuable traits of the crop in the conditions of the Central Chernozem region was studied. The highest yield – 2.42 t/ha (on average for four years) was obtained on the variant the seed inoculation and the treatment of seeds and vegetative soybean plants with a microfertilizer Microvit St were applied. The yield increase in this variant was 0.68 t/ha or 39.1%. The higher amounts of crude protein in soybean seeds were observed in variants where seeds were treated with an inoculant (29.3–32.3%). The greatest difference compared to the control was noted in the variants: Background + Microvit St (seed treatment) + (Microvit Zn + Microvit B (plant treatment); Background + Microvit St (seed treatment + plant treatment), it was 4.2% and 3.5%, respectively. The highest protein yield in the soybean crop was obtained also on the abovementioned variants – 0.77 t/ha and 0.75 t/ha, respectively. The fat content in soybean seeds did not depend on the treatment with preparations and averaged 25.3%. The usage of innovative preparations allowed reducing the prime cost of seeds by 1.82–5.09 thousand RUR/ton and increasing the level of profitability by 15–51% compared to the control variant. As a result of the application of technological practices, an increase in plants preservation by the end of the growing season was noted, the 1000 seeds weight increased and the quality indicators of soybean seeds improved.
The promising strains antagonists of Phoma rot pathogen on sunflower: estimation of phytotoxicity and growth-stimulating activity
Authors:   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Maslienko L.V. , Efimtseva E.A. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Deynega L.A. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops
Published: July 2023

The phytotoxicity and growth stimulating activity of promising strains antagonists of a Phoma pathogen on sunflower seedlings were estimated. Soaking of sunflower seeds and seedlings in suspensions of fungi and bacteria-antagonists did not have a depressing effect on seed germination and wilting of seedlings. Three bacterial strains antagonists from a genus Bacillus: 5-3, K 1-2, and 5B-1 Bacillus sp., and two strains from a genus Pseudomonas: Oif 2-1 and 14-3 Pseudomonas sp. showed the maximal authentic increase (by 10.0–14.0%) in seed germination (94.0–98.0% at germination in a control 84.0%). Only two fungal strains antagonists: Xk-1 Chaetomium sp. and A-1 Basidiomycota, showed verifiable increase (by 6%) in seed germination (90%). The verifiable stimulating effect of antagonists on root weight was stated. The bacterial strains 11-1, D-10, and 5-3 Bacillus sp. (150.0–166.7%) and fungal ones Xk-1 Chaetomium sp. and Pbc-1 Penicillium sp. (133.3–150.0%) showed the best results comparing to the control.
The new sunflower cultivar Saratovsky 21
Authors:   Federal Center of Agriculture Research of the South-East Region, Buenkov A.Yu. , Kudryashov S.P. ,   Federal Center of Agriculture Research of the South-East Region, Lekarev A.V. ,   Federal Center of Agriculture Research of the South-East Region
Published: July 2023

Breeders of the Federal Center of Agriculture Research of the South-East Region developed a promising sunflower cultivar Saratovsky 21. The vegetative period is 92–95 days. Over the years of the study according to the method of the competitive variety testing, the seed and oil yields of the cultivar Saratovsky 21 exceeded the standard cultivar Skorospely 87 by 0.3 t/ha and 0.2 t/ha, respectively. It also exceeded the cultivar Saratovsky 20 in terms of yield and oil yield by 0.1 t/ha. Cultivar Saratovsky 21 is included into the State Register of Breeding Achievements in 2023 and approved for production in the Low Volga (8th) region.
The hybrid of the ornamental sunflower Sirius bred in the V.S. Pustovoit All-Russian Research Institute of Oil Crops
Authors:   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Peretyagina T.M. , Chebanova Yu.V. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Demurin Ya.N. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Zemtseva T.A. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops, Epishkina A.V. ,   V.S. Pustovoit All-Russian Research Institute of Oil Crops
Published: July 2023

The hybrid of the ornamental sunflower Sirius was obtained as a result of crossing two parent lines LD10 (variety of the ornamental sunflower Zhemchuzhny) and LD20. The main ornamental features of the hybrid Sirius are the original inflorescence, the light-yellow color of the ray flowers, the purple color of the tubular flowers, and the compact habitus. The hybrid belongs to the middle maturing group. The originator of the ornamental sunflower hybrid Sirius is the V.S. Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK).
Incontinência urinária no adulto: aspectos, impacto na qualidade de vida e o papel da enfermagem
Authors: Gomes Braga Francisca das Chagas Sheyla Almeida , Silva Grazielle Roberta Freitas da , Carvalho Sabrina de Oliveira , Tavares Cléciton Braga , Santos Maria Lailda de Assis , Sousa Naiana Lustosa de Araújo
Published: July 2023

Objetivo: Conhecer os principais aspectos da incontinência urinária no adulto, seu impacto na qualidade de vida e o papel da enfermagem. Revisão bibliográfica: A partir da análise do conteúdo do artigos foram elencadas três categorias: Aspectos da Incontinência Urinária no adulto, incluindo os tipos de tratamento, combinados ou isolados, tais como cirúrgicos, medicamentosos e comportamentais; Impacto da incontinência urinária na qualidade de vida, sendo observada como um problema de saúde pública que precisa ser combatido para minimizar danos e transformar a realidade das pessoas que apresentam essa condição; e O papel da enfermagem no cuidado ao paciente com incontinência urinária, destacando sobretudo a importância do enfermeiro no enfrentamento da IU. Considerações finais: A incontinência urinária, tida como um problema multifatorial, atinge um número expressivo da população adulta, devendo ser avaliada individualmente por especialistas. Diante disso, a enfermagem atua desde a implementação de estratégias de prevenção até a avaliação e promoção de cuidados, visando minimizar danos físicos, psicológicos e sociais e, desta forma, promovendo a melhoria da qualidade de vida destes indivíduos.
THE PROBLEM OF PELVIC ORGAN DISTENSION AND STAGE I-II GENITAL PROLAPSE IN WOMEN OF REPRODUCTIVE AGE AND IN POSTMENOPAUSE (LITERATURE REVIEW)
Authors:   City polyclinic № 3, Grodno, Belarus, Lazuta G. S. , Gurin A. L. ,   Grodno State Medical University, Grodno, Belarus
Published: July 2023

Introduction. Genital prolapse is a problem affecting not only the field of gynecology, but also urology, proctology, surgery. At the moment, there are many methods of surgical and conservative treatment, which are becoming more and more effective, minimally invasive operations have been widely introduced into practice . This significantly improves the quality of life of patients, but is associated with the development of a number of complications, the woman's unwillingness to perform surgery, and the inability to completely eliminate the cause of the pathological condition. Timely correction of prolapse in the early stages improves the quality of life of patients to a greater extent, is able to eliminate the cause of distention and prolapse in the early stages. Knowledge of the basics of pathogenesis will help to correctly prescribe treatment that not only eliminates the symptoms, but also the cause of the disease. The purpose of the work. To analyze the results of scientific works on the problem of distension and prolapse of pelvic organs of the I and II degrees. Material and methods. A qualitative analysis of 46 Russian-language and English-language sources, which reflect different aspects of the problem of distension and prolapse of I and II degrees, was carried out. Results. It has been established that due to the lack of a certain algorithm of actions, women are either not provided with assistance at the distance and at the early stage of prolapse, or they are not provided in full. Conclusions. Timely diagnosis, identification of risk factors for the development of distension and prolapse of pelvic organs helps to carry out not only therapeutic, but also preventive measures more efficiently, which preserves the health of a woman, prevents the development of depression. In addition, properly selected conservative treatment, training women to use pessaries independently (correctly introduce, conduct hygiene measures) and perform exercises, including with the help of special trainers to strengthen the pelvic floor muscles in the early stages of prolapse, reduce the percentage of operations that are accompanied by a number of complications.
HOSPITAL SUICIDES: SIGNIFICANCES AND MEANINGS
Authors:   Grodno Regional Clinical Center “Psychiatry-Narcology”, Grodno, Belarus, Bukin S. I.
Published: July 2023

Purpose. To define relationship between the frequency of suicides among the population and the frequency of suicides committed by patients of healthcare organizations providing medical care in hospitals. Material and methods. The work used statistical data for the Grodno region for the period 2006-2022: on the population, the number of suicides, data on hospital suicides (n=33). Results. It has been established that at monthly intervals the frequency of registration of hospital suicides corresponds to the frequency of suicides among the population. The identity of the medical and psychological portraits of patients who committed hospital suicides and suicides in the Grodno region, as well as the high frequency of suicides at the place of residence of patients who committed hospital suicides indicate the random choice of the suicide site by the suicider during inpatient treatment. Conclusions. The relationship defined in the study indicate the dominant role of sociogenesis in the presuicide of hospital suicides.
IMPROVEMENT OF THE TECHNIQUE OF BYPASS INTERVENTIONS ON THE FEMOROPOPLITEAL SEGMENT IN PATIENTS WITH CHRONIC ARTERIAL INSUFFICIENCY OF THE LOWER LIMB
Authors:   Grodno State Medical University, Grodno, Belarus, Panasiuk O. V.
Published: July 2023

Background: Despite the increasing number of X-ray endovascular operations on infrainguinal lesions of lower limb arteries open surgery remains highly relevant. The operating time of open surgeries cannot be considered satisfactory, especially when combined shunts are used in the infrainguinal position. Research objective is to improve the results of shunt operations at atherosclerotic lesions of the femoropopliteal segment by advancing the technique of determining the required extent and applying the autotransplant material. Material and methods. 72 patients were involved in the research. All the patients underwent the femoropopliteal shunt procedure. The instruments designed by us (autovenous shunt length meter and the device for tunnel formation and for applying the shunt into the tissues) were used in the first group. Patients from the second group were operated on with the use of the classical technique and equipment. Results. No combined shunts were used in the first group of patients in comparison with the second group (n=5). Statistically significant results (p<0.05) between the studied groups were obtained according to such criteria as number of cases of intraoperative shunt torsion (p=0.0171), length of unused autograft material (p=0.0001), ankle brachial index increase (p=0.024), the number of early postoperative complications (p=0.028), the number of shunt dysfunctions (p=0.0203) and shunt functioning duration (p=0.013). Conclusions. The use of the patented instruments when performing femoropopliteal shunting allows to determine precisely the required amount of autotransplanted material and to provide its more convenient applying in the subcutaneous tunnel. The use of the patented instruments when performing femoropopliteal shunting with a reversed autovein made it possible to improve the technique of this revascularization operation: to accurately determine the required amount of autograft material which excluded the presence of patients with combined shunt in the first group, as well as to perform the simultaneous creation of a tunnel in the soft tissues of the thigh, shin and reliable shunt placement, excluding it’s rotation along the axis. The use of the patented instruments when performing femoropopliteal shunting allowed to get positive results in the first group, in comparison with second group of patients both in the early and late postoperative periods.
ANALISIS PENGGUNAAN INSENTIF PPH FINAL UMKM SEBAGAI SALAH SATU PROGRAM PEMULIHAN EKONOMI NASIONAL TERHADAP PENERIMAAN PAJAK DI KPP PRATAMA PANGKAL PINANG
Authors: Sepa Ade Emilya , Safrizal Safrizal
Published: July 2023

On May 31, 2020 the government issued a policy as a form of effort as well as a legal umbrella program aimed at overcoming national economic and health problems as a result of the corona virus, namely the Covid-19 Handling Program and National Economic Recovery. One of these programs is to provide support for small and medium enterprises to continue to run their business as a step that can support the movement of the national economy. This support is carried out by providing tax incentives in the form of Final PPh borne by the government. The tax that is borne is the tax that is imposed based on Government Regulation Number 23 of 2018. The incentive was initially given during the April 2020 Tax Period until the September 2020 Tax Period, then the government issued apolicy again so that the incentive could be used until December 2021. Not until there in 2022 the government again issued a policy that regulates the granting of tax-free facilities to individual Final Income Tax having accumulated turnover in one tax year not exceeding IDR 500,000,000.00. This facility is expected to be used optimally by business actors and can ease the burden by increasing their income. However, in reality the use of this incentive has not been implemented by all MSME actors, including taxpayers in the Pangkal Pinang KPP Pratama work area. And this is directly proportional to the contribution of the final PPh tax payment borne by the government towards the realization of KPP revenues.
Aneurisma da veia porta intra-hepática – diagnóstico ultrassonográfico / Intrahepatic portal vein aneurysm – ultrasonographic diagnosis
Authors: Duarte Márcio Luís , Duarte Élcio Roberto
Published: July 2023

Introdução: Os aneurismas do sistema venoso portal representam 3% de todos os aneurismas venosos. Os locais mais comuns nos quais os aneurismas do sistema venoso portal se desenvolvem são a veia porta principal e a confluência das veias esplênica e mesentérica superior, seguidas pelo hilo hepático. Objetivo: Relatar um caso e revisar a literatura acerca deste aneurisma incomum. Relato do Caso: Mulher de 76 anos com quadro de confusão mental e dificuldade para deambular há uma hora, cuja ultrassonografia abdominal detectou aneurisma da veia porta intra-hepática, com aumento do calibre no hilo hepático, importante vascularização colateral e esplenomegalia com veia esplênica de calibre aumentado, caracterizando hipertensão portal. Conclusão: O aneurisma intra-hepático da veia porta é uma  lesão incomum, diagnosticada pela ultrassonografia à beira do leito, sem a necessidade de deslocamento da paciente para a tomografia computadorizada.Palavras Chave: Aneurisma, Veia porta, Diagnóstico, Ultrassonografia
ABSTRACT
Introduction: Portal venous system aneurysms represent 3% of all venous aneurysms. The most common sites at which portal venous system aneurysms develop are the main portal vein and the confluence of the splenic and the superior mesenteric veins, followed by the hepatic hilum. Objective: To report a case and review the literature about this uncommon aneurysm. Case report: A 76-year-old woman with mental confusion and difficulty walking for one hour, whose abdominal ultrasound detected an increase in the caliber of the portal vein in the hepatic hilum, with an important collateral vascularization and intrahepatic portal vein aneurysm splenomegaly with the splenic vein of increased caliber, characterizing portal hypertension. Conclusion: Intrahepatic portal vein aneurysm is an uncommon lesion diagnosed by bedside ultrasonography without the need to transfer the patient for computed tomography.Keywords: Aneurysm, Portal vein, Diagnosis, Ultrasonography
A Hybrid Machine-Learning Approach to Predict the Site Selectivity of Iridium-Catalyzed Arene Borylation
Authors: Caldeweyher Eike , Elkin Masha , Gheibi Golsa , Johansson Magnus , Sköld Christian , Norrby Per-Ola , Hartwig John
Published: July 2023

The borylation of aryl and heteroaryl C–H bonds is valuable for the site-selective functionalization of C–H bonds in complex molecules. Iridium catalysts ligated by bipyridine ligands catalyze the borylation of the aryl C–H bonds that are most acidic and least sterically hindered, but predicting the site of borylation in molecules containing multiple arenes is difficult. To address this challenge, we report a hybrid computational model that predicts the Site of Borylation (SoBo) in complex molecules. The SoBo model combines density functional theory, semi-empirical quantum mechanics, cheminformatics, linear regression, and machine learning to predict site selectivity and to extrapolate these predictions to new chemical space. Experimental validation of SoBo showed that the model predicts the major site of borylation of pharmaceutical intermediates with higher accuracy than prior machine-learning models or human experts, demonstrating that SoBo will be useful to guide experiments for the borylation of specific C(sp2)–H bonds during pharmaceutical development.
Cyclic(Alkyl)(Amino)Carbene Stabilized Gold Nanoparticles: Efficient Catalyst for Selective Electrochemical Reduction of CO2 to CO
Authors: Ghosh Moushakhi , Saha Paramita , Roy Sumit , Pillai Pramod , Dey Abhishek , Khan Shabana
Published: July 2023

Electrochemical reduction of CO2 to value-added products is an important area for sustainable energy research. The nanomaterials offer a wide variety of catalysts for this task. In this work, we have synthesized an extremely electron-rich cyclic(alkyl)(amino)carbene (CAAC) stabilized gold nanoparticles (AuNPs) and utilized them for the electrochemical reduction of CO2. This newly prepared CAAC functionalized AuNP catalyst demonstrates a remarkable faradaic efficiency (FE) of 94% towards selective carbon monoxide (CO) formation (at pH 6.3, 2 hr of controlled potential electrolysis at -0.7 V vs NHE). Our results establish CAAC as a promising ligand for surface functionalization of AuNPs through the strong σ-donation, which enhances the electrocatalytic properties and set a platform for further developing persistent carbenes as the universal ligands.
Discovery of fungal onoceroid triterpenoids through domainless enzyme-targeted global genome mining
Authors: Tang Jia , Matsuda Yudai
Published: July 2023

Genomics-guided methodologies have been widely adopted and proven beneficial for the discovery of natural products. However, a major challenge in the field of genome mining is determining how to selectively extract biosynthetic gene clusters (BGCs) for untapped natural products from a substantial number of available genome sequences. In this study, we developed a fungal genome mining pipeline that extracts BGCs encoding enzymes that lack a detectable protein domain and are not recognized as biosynthetic proteins by existing bioinformatic tools. We searched for BGCs encoding a homologue of Pyr4-family terpene cyclases, which are representative examples of domainless enzymes, in approximately 2,000 fungal genomes and discovered several BGCs with unique features. The subsequent characterization of these BGCs led to the discovery of the first fungal onoceroid triterpenoids and unprecedented onoceroid synthases. Our genome mining pipeline has broad applicability in fungal genome mining and can serve as a beneficial tool for accessing diverse, unexploited natural products.
Enantioselective Total Syntheses of Cassane Furanoditerpenoids and their Stimulation of Cellular Respiration in Brown Adipocytes
Authors: Carreira Erick , Bulthaupt Hendrik Helmut , Glatz Fabian , Papidocha Sven Michael , Wu Chunyan , Teh Shawn , Wolfrum Susanne , Balazova Lucia , Wolfrum Christian
Published: July 2023

We report the first and enantioselective total syntheses of (+)-1-deacetylcaesalmin C, (+)-δ-caesalpin, (+)-norcaesalpinin MC, and (+)-norcaesalpinin P. Salient features of the synthetic strategy are exo-selective intramolecular Diels–Alder reaction of a furanoquinone monoketal and subsequent chemoselective reduction of the resulting pentacyclic furfuryl ketal furnishing a keystone intermediate. The latter enables access to the collection of natural products through implementation of stereoselective oxidations. Having accessed the cassane furanoditerpenoids, we unveil previously unknown bioactivity: (+)-1-Deacetylcaesalmin C stimulates respiration in brown adipocytes, which has been suggested to play a central role in treatment of obesity.
Origin-Independent Dynamic Polarizability Density from Coupled Cluster Response Theory
Authors: Summa Francesco Ferdinando , Andersen Josefine H. , Lazzeretti Paolo , Sauer Stephan P. A. , Monaco Guglielmo , Coriani Sonia , Zanasi Riccardo
Published: July 2023

The calculation of the origin-independent dynamic electric dipole polarizability, previously presented for uncorrelated and density functional theory (DFT) based methods, has been developed and implemented at Coupled Cluster Singles and Doubles (CCSD) level of theory. The pointwise analysis of polarizability densities calculated for a number of molecules at Hartree-Fock (HF) and CCSD clearly shows that the electron correlation effect is much larger than one would argue considering the integrated dipole electric polarizability alone. Large error compensations occur during the integration process, that hide fairly large deviations mainly located in the internuclear regions. The same is observed comparing calculated CCSD and B3LYP polarizability densities, with the remarkable feature that positive/negative deviations between CCSD and HF reverse sign, becoming negative/positive when comparing CCSD to B3LYP.
Preparing chaperone—client protein complexes for biophysical and structural studies
Authors: Sučec Iva , Schanda Paul
Published: July 2023

Many proteins are prone to misfolding or unfolding and aggregation in the aqueous environment of the cell, either due to their complex ternary structure, cellular localization, molecular crowding, cellular stress, or their intrinsic hydrophobic nature. Molecular chaperones are involved in biogenesis of such proteins, and in ensuring their intactness throughout their life cycle. While there are many different types of chaperones with various cellular roles, essentially all of them are characterized by a basic “holdase” function, i.e. the ability to bind to proteins that are generally in some non-native conformation – often these are called “client” proteins. Understanding how these complexes form, what (residual) structure the client proteins have when bound, and how the client protein may eventually be released again from the chaperone is essential for resolving questions in biogenesis of cells and organelles. The preparation of chaperone complexes for in vitro studies is essential for characterising their function at the structural level. However, preparing these complexes is often a significant challenge in itself. Here, we propose a systematic view of the factors that can counteract chaperone--client complex formation, and identify possible routes for generating such complexes. We review the various methods that have been used in previous studies. This review will be of interest for anyone trying to obtain chaperone complexes for structural or biochemical studies.
CALCULATION OF AUTOMOBILE TRANSPORT EMISSIONS INTO ATMOSPHERIC AIR (ON THE EXAMPLE OF THE CITY OF TVER)
Authors: Черемухин Д.Д. , Тихомиров О.А. , Муравьева Л.В.
Published: July 2023

На основе авторских данных и выполненных расчетов проведен анализ интенсивности движения автомобильного транспорта в пределах г. Твери. Выполнены расчеты уровня загрязнения приземного слоя атмосферного воздуха согласно утвержденной методике ГОСТ Р 56162–2019, а также расчет рассеивания с использованием программы УПРЗА «Эколог»

Based on our own collected data and performed calculations in 2022. The analysis of the intensity of traffic of motor transport within the city of Tver was carried out, calculations of the level of pollution of the surface layer of atmospheric air were performed according to the approved methodology. The calculation of dispersion was performed using the software program "Ecolog".
ASSESSMENT OF HYDROCHEMICAL PARAMETERS VOLGA RIVER NEAR THE CITY OF TVER
Authors: Тихомиров О.А.
Published: July 2023

Проведен анализ гидрохимических параметров и качества воды в ряде створов р. Волги в пределах Иваньковского и Угличского водохранилищ. Выявлены превышения ПДК по ряду показателей на всем протяжении реки ниже г. Твери. Дана оценка уровня загрязнения водотока и влияния антропогенных факторов на гидрохимический режим реки Волги в пределах Тверского региона.

The analysis of hydrochemical parameters and water quality in a number of Volga River channels within the Ivankovsky and Uglich reservoirs is carried out. The exceedances of the MPC for a number of indicators were revealed along the entire length of the river below the city of Tver. The assessment of the level of pollution of the watercourse and the influence of anthropogenic factors on the hydrochemical regime of the Volga River within the Tver region is given.
INFLUENCE OF THE PROPERTIES OF THE POLYMER MATRIX OF THE CATALYST ON THE PROCESSING OF PLANT BIOMASS
Authors: Филатова А.Е. , Сульман А.М. , Шиманская Е.И. , Гребенникова О.В. , Монжаренко М.А.
Published: July 2023

В настоящее время усилия многих научных коллективов сосредоточены на разработке новых, эффективных и экологически безопасных способов получения полиспиртов из растительной биомассы, в первую очередь, из целлюлозы. Огромные природные возобновляемые запасы данного биополимера способны полностью удовлетворить потребности современной промышленности в полиспиртах, что особенно актуально с учётом перспективы постепенного истощения запасов углеводородных ископаемых. Одностадийный гидрогенолиз целлюлозы до полиспиртов (one-pot процесс), в присутствии гетерогенных металлосодержащих катализаторов известен достаточно давно, однако до сих пор остается немаловажным фактором эффективность используемого металлосодержащего катализатора. Результаты многочисленных исследований показывают, что наиболее перспективными являются катализаторы, содержащие рутений, однако вопрос оптимальной подложки остаётся пока открытым. В данной работе проводятся исследования направленные на изучение влияние физико-химических свойств подложки на процесс гедрогенолиза целлюлозы.

Currently, the efforts of many research teams are focused on the development of new, effective and environmentally friendly methods for obtaining polyalcohols from plant biomass, primarily from cellulose. Huge natural renewable reserves of this biopolymer are able to fully meet the needs of modern industry in poly-alcohols, which is especially important given the prospect of gradual depletion of hydrocarbon reserves. Single-stage hydrogenolysis of cellulose to poly alcohols (one-pot process) in the presence of heterogeneous metalcontaining catalysts has been known for a long time, but the efficiency of the metal-containing catalyst used still remains an important factor. The results of numerous studies show that catalysts containing ruthenium are the most promising, but the question of the optimal substrate remains open for now. In this paper, studies are conducted aimed at studying the influence of the physicochemical properties of the substrate on the process of cellulose hedrogenolysis.
Childhood Exposure to Violence and Nurturing Relationships: The Long-Run Effects on Black Men
Authors: Aliprantis Dionissi , Tauber Kristen N.
Published: July 2023

Black men who witnessed a shooting before turning 12 have household earnings as adults 31 percent lower than those who did not. We present evidence that this gap is causal and is most likely the result of toxic stress; it is not mediated by incarceration and is constant across neighborhood socioeconomic status. Turning to mechanisms related to toxic stress, we study exposure to violence and nurturing relationships during adolescence. Item-anchored indexes synthesize variables on these treatments better than summing positive responses, Item Response Theory, or Principal Components, which all perform similarly. Providing adolescents with nurturing relationships is almost as beneficial as preventing their exposure to violence.