bluuebunny/crossref_metadata_2025 huggingface dataset:
Chronic cluster headache: A study of the telencephalic and cerebellar cortical thickness
Authors: Demichelis Greta , Pinardi Chiara , Giani Luca , Medina Jean Paul , Gianeri Ruben , Bruzzone Maria Grazia , Becker Benjamin , Proietti Alberto , Leone Massimo , Chiapparini Luisa , Ferraro Stefania , Nigri Anna
Published: December 2021

Purpose

Previous studies on brain morphological alterations in chronic cluster headache revealed inconsistent findings.

Method

The present cross-sectional explorative study determined telencephalic and cerebellar cortex thickness alterations in a relatively wide sample of chronic cluster headache patients (n = 28) comparing them to matched healthy individuals.

Results

The combination of two highly robust state-of-the-art approaches for thickness estimation (Freesurfer, CERES), strengthened by functional characterization of the identified abnormal regions, revealed four main results: chronic cluster headache patients show 1) cortical thinning in the right middle cingulate cortex, left posterior insula, and anterior cerebellar lobe, regions involved in nociception's sensory and sensory-motor aspects and possibly in autonomic functions; 2) cortical thinning in the left anterior superior temporal sulcus and the left collateral/lingual sulcus, suggesting neuroplastic maladaptation in areas possibly involved in social cognition, which may promote psychiatric comorbidity; 3) abnormal functional connectivity among some of these identified telencephalic areas; 4) the identified telencephalic areas of cortical thinning present robust interaction, as indicated by the functional connectivity results, with the left posterior insula possibly playing a pivotal role.

Conclusion

The reported results constitute a coherent and robust picture of the chronic cluster headache brain. Our study paves the way for hypothesis-driven studies that might impact our understanding of the pathophysiology of this condition.
The impact of COVID-19 on surgical volume and surgical training at a high-volume pelvic oncology centre
Authors: Abou-Chedid Wissam , Nason Gregory J , Evans Andrew T , Yamada Kohei , Moschonas Dimitrios , Patil Krishna , Langely Stephen E , Perry Matthew JA
Published: December 2021

Introduction:

The coronavirus (COVID-19) pandemic has overwhelmed most health services. As a result, many surgeries have been deferred and diagnoses delayed. The aim of this study was to assess the effect of the COVID-19 pandemic at a high-volume pelvic oncology centre.

Methods:

A retrospective review was performed of clinical activity from 2017 to 2020. We compared caseload for index procedures 2017–2019 (period 1) versus 2020 (period 2) to see the effect of the COVID pandemic. We then compared the activity during the first lockdown (March 23rd) to the rest of the year when we increased our theatre access by utilising a ‘clean’ site.

Results:

The average annual number of robotic assisted radical cystectomy (RARC) and robotic assisted radical prostatectomy (RARP) performed during period 1 was 82 and 352 respectively. This reduced to 68 (17.1% reduction) and 262 (25.6% reduction) during period 2. The number of patients who underwent prostate brachytherapy decreased from 308 to 243 (21% reduction). The number of prostate biopsies decreased from 420 to 234 (44.3% reduction). The number of radical orchidectomies decreased from 18 to 11 (39% reduction). The mean number of RARC and RARP per month during period 2 was 5.5 and 22. This decreased to 4 and 9 per month during the first national lockdown but was maintained thereafter despite two further lockdowns.

Conclusion:

There has been a substantial decrease in urological oncology caseload during the COVID pandemic. The use of alternate pathways such as ‘clean’ sites can ensure continuity of care for cancer surgery and training needs.
Examining the Gap Between Prosecutor Attitudes and Decisions: Case Prioritization Through Case Elimination Mechanisms in Driving With a Suspended License Cases
Authors: Arndt Maria E.
Published: December 2021

Prosecutors are granted considerable discretion, particularly for misdemeanors. The current study assesses the processing of misdemeanor driving with suspended license (DWSL) cases. Using interview and administrative data from a Florida jurisdiction, the study first examines prosecutorial attitudes about case elimination mechanisms—declination, dismissal, and diversion—then evaluates the extent to which prosecutors’ views about handling DWSL cases and racial disparities in the legal system are reflective of case processing outcomes. Results indicate prosecutors view case prioritization as important, though it is unclear how they achieve it. Despite a reluctance to decline cases when the elements of an offense are supported by evidence, prosecutors acknowledge they cannot pursue all offenses if there is only marginal public safety return. Contemporaneous administrative data show that DWSL cases were routinely pursued in 2017: nearly all DWSL cases were filed, a third were dismissed, and 11% were diverted. Regression analysis also demonstrates that prosecutors’ views on racial and ethnic disparities are somewhat aligned with the case processing decisions for DWSL cases processed in 2017. These findings are discussed in terms of their implications for prosecutorial policy, practice, and the effects of prosecutorial discretion for low-level cases on communities.
Application of a ‘Recycling Exchange’ instrument to compensate waste pickers in Brazil via a first payment for urban environmental services programme
Authors: Dias Alice Libânia S , Lange Lisete Celina , Magalhães Aline Souza
Published: December 2021

This article presents an approach to compensate waste pickers in the informal sector of Minas Gerais state, Brazil, via a Payment for Urban Environmental Services (PUES) instrument, called ‘Recycling Exchange’. The aim is to evaluate the effects of this instrument on the amount of waste diverted from landfill and reintroduced into the production chain, and to increase recognition of waste pickers’ contributions to the state’s economy. It was found that the ‘Recycling Exchange’ met the fundamental objectives of a PUES: the double social and economic benefits of the social inclusion of waste pickers in the execution of the public policy for solid waste management, and inducing (in the case of glass), ensuring and stabilising (plastic and paper) continuity of the activity of selling recyclables in times of wide price fluctuations for these recyclables. The instrument enhanced the provision of this environmental service and the positive externalities associated with recycling.
Using a Resistance Lens to Understand Performative Compliance of Low-Income Lone Mothers
Authors: Vilches Silvia L. , Pulkingham Jane
Published: December 2021

The agency of lone mothers who rely on government income supports is often erased by the discourse of dependency, especially under welfare-to-work eligibility criteria. Here we apply the concept of small acts of micro-resistance in constrained circumstances, augmented by conceptualization of resistance as conscious oppositionality and intentionality to understand the agency of lone-mothers who receive income-assistance (IA) as they make-do and raise children under state- and market-enforced rules. Using a resistance lens reveals the interconnected importance of everyday acts like “talking back” to income-support staff, surreptitious gleaning of goods for resale, and re-storying the self. We describe these in three modalities: resistance as evasion and subterfuge; resistance through asserting positive identities; and resistance in forging their own path. Using a conceptual framework of resistance reveals the extent to which women’s survival and capacity to raise children are contingent on a performance of compliance, demonstrating the impacts of welfare-to-work on female-headed lone parent families.
Parameters uncertainty in pareto optimization of nonlinear inerter-based suspension system under nonstationary random road excitation
Authors: Seifi Abolfazl , Hassannejad Reza
Published: December 2021

Ignoring the possible impacts of uncertainties in vehicle components during the design phase can undermine the safety of passengers and the vehicle performance. The main function of a suspension system is to provide satisfactory ride comfort and road-holding with a sufficiently low probability of rollover. Despite many studies on the design of new suspension systems with inerters, the effect of uncertainties in vehicle weight and tire stiffness on the design of suspension with inerters has not received much attentions. This paper presents a new type of suspension with inerters and asymmetric dampers and investigates the dynamic behavior of a vehicle under variable vehicle speed. Moreover, the effect of uncertainties on the choice of acceptable values of inerters is evaluated. For this investigation, the authors developed a 9-DOF full vehicle model with roll and yaw motions under non-stationary random road excitations in the time and frequency domains and studied its dynamic response with different suspension models. The optimal design was performed using a multi-objective optimization algorithm called MOEA/D. The best model was then used to determine the effect of uncertainties on the choice of inerters. The optimization results show that using the optimized suspension with inerters and nonlinear dampers instead of conventional design improves the ride comfort by 0.16%, the vehicle road-holding by 3.54%, and the rollover probability by 44.73%. In the proposed model, by changing the values of vehicle parameters with uncertainty, the choice of inerters to have an acceptable performance would be variable.
Driver-like decision-making method for vehicle longitudinal autonomous driving based on deep reinforcement learning
Authors: Gao Zhenhai , Yan Xiangtong , Gao Fei , He Lei
Published: December 2021

Decision-making is one of the key parts of the research on vehicle longitudinal autonomous driving. Considering the behavior of human drivers when designing autonomous driving decision-making strategies is a current research hotspot. In longitudinal autonomous driving decision-making strategies, traditional rule-based decision-making strategies are difficult to apply to complex scenarios. Current decision-making methods that use reinforcement learning and deep reinforcement learning construct reward functions designed with safety, comfort, and economy. Compared with human drivers, the obtained decision strategies still have big gaps. Focusing on the above problems, this paper uses the driver’s behavior data to design the reward function of the deep reinforcement learning algorithm through BP neural network fitting, and uses the deep reinforcement learning DQN algorithm and the DDPG algorithm to establish two driver-like longitudinal autonomous driving decision-making models. The simulation experiment compares the decision-making effect of the two models with the driver curve. The results shows that the two algorithms can realize driver-like decision-making, and the consistency of the DDPG algorithm and human driver behavior is higher than that of the DQN algorithm, the effect of the DDPG algorithm is better than the DQN algorithm.
Noise Increases Anchoring Effects
Authors: Lee Chang-Yuan , Morewedge Carey K.
Published: December 2021

We introduce a theoretical framework distinguishing between anchoring effects, anchoring bias, and judgmental noise: Anchoring effects require anchoring bias, but noise modulates their size. We tested this framework by manipulating stimulus magnitudes. As magnitudes increase, psychophysical noise due to scalar variability widens the perceived range of plausible values for the stimulus. This increased noise, in turn, increases the influence of anchoring bias on judgments. In 11 preregistered experiments ( N = 3,552 adults), anchoring effects increased with stimulus magnitude for point estimates of familiar and novel stimuli (e.g., reservation prices for hotels and donuts, counts in dot arrays). Comparisons of relevant and irrelevant anchors showed that noise itself did not produce anchoring effects. Noise amplified anchoring bias. Our findings identify a stimulus feature predicting the size and replicability of anchoring effects—stimulus magnitude. More broadly, we show how to use psychophysical noise to test relationships between bias and noise in judgment under uncertainty.
Translating Boris Vian's Vercoquin et le plancton: Does it mean a thing if it ain’t got that swing?
Authors: Bradford Terry J
Published: December 2021

This article is the result of research and reflection undertaken in the process of translating Vercoquin et le plancton. Focusing on music-related references in Boris Vian's first published novel, this article will discuss different layers of meaning and a variety of techniques that can be discerned in Vian's punning and wordplay. The complexity and compactness of his writing make for an exceptional case study. Whilst much of the wordplay may justifiably be classed as ‘juvenile’, its many facets also reflect life in Occupied France, document the Zazou movement, voice a manifesto for jazz, and stage playfulness that can be viewed as ranging from the very silly to a form of resistance. Such sophistication – largely overlooked, hitherto – justifies re-evaluation of Vian's early work. Analysis of a number of challenges to translation gives rise to discussion of possible solutions, based on different considerations – genre, function and audience – and using different ‘tools’. This article seeks not to justify my own choices in translation. Rather, it should illustrate the point that research is essential, and that interpretation and creativity are necessary if one's strategy in literary translation is to try to provide a new audience with similar opportunities for their own readings as a Francophone audience might have.
Shifting Accounts of Justice: The Legalisation and Politicisation of International Criminal Justice
Authors: Redwood Henry , Goozee Hannah
Published: December 2021

In December 2015, the International Criminal Tribunal for Rwanda delivered its final verdict in Butare, bringing the International Criminal Tribunal for Rwanda to a close after 21-years. Despite the important role that the tribunal played in confirming international criminal justice as a key transitional justice mechanism, and tool of international peace and security, there has been little retrospective analysis of the court’s history. This article draws on a Bourdieusian field analysis to address the absence and makes two contributions. First, it demonstrates that over the International Criminal Tribunal for Rwanda’s history the tribunal’s conception of justice shifted from a weak form of restorative justice to a more traditional form of retributive justice. Second, it reveals that this shift was the result of a ‘settling’ on the law and, more importantly, UN Security Council interventions. This legalisation and politicisation of trial practice saw a shift in the field from prioritising moral authority to legal and delegated authority.
Dignity and attitudes to aging: A cross-sectional study of older adults
Authors: Kisvetrová Helena , Mandysová Petra , Tomanová Jitka , Steven Alison
Published: December 2021

Background: Dignity is a multidimensional construct that includes perception, knowledge, and emotions related to competence or respect. Attitudes to aging are a comprehensive personal view of the experience of aging over the course of life, which can be influenced by various factors, such as the levels of health and self-sufficiency and social, psychological, or demographic factors. Aim: The purpose of this study was to explore the attitudes to aging of home-dwelling and inpatient older adults, and whether dignity and other selected factors belong among the predictors influencing attitudes to aging in these two different groups of older adults. Research design: Cross-sectional study using a set of questionnaires: Patient Dignity Inventory, Attitudes to Aging Questionnaire, and Barthel Index. Pearson and Spearman correlation analyses and multivariable linear regression were used for statistical processing. Participants and research context: 233 inpatients and 237 home-dwelling older adults participated in the research in two regions of the Czech Republic. Ethical considerations: Institutional Review Board approval was received from the authors’ university. Findings: The inpatients had more negative attitudes to aging (M = 74.9±10.9; P <0.0001). The predictors of their attitudes to aging were gender and dignity. Women ( β = −2.969, P = 0.045) and inpatients with poor dignity ratings ( β = −0.332, P <0.0001) had more negative attitudes to aging. The predictors for home-dwelling older adults were education, living arrangement, and dignity. More negative attitudes to aging were found in older adults with lower levels of education ( β = 2.716, P = 0.007) who lived alone ( β = 2.163, P = 0.046) and rated their dignity as low ( β = −0.325, P <0.0001). Discussion and Conclusions: The results of this study add to the understanding that a sense of dignity is an important predictor of attitudes to aging for both home-dwelling older adults and inpatients.
A hybrid linear actuator based on screw clamp operation principle: Design and experimental verification
Authors: Shi Yunlai , Sun Haichao , Cheng Dingji , Zhang Jun , Lin Yuyang , Sun Han
Published: December 2021

This paper presents a hybrid linear actuator using screw clamp operation principle. The actuator mainly consists of a hollow electromagnetic torque motor located between two clamping nuts, two hollow cylindrical shaped piezoelectric stacks symmetrically configured at two ends of the actuator and a feed-screw (also considered as the mover of the actuator) assembled throughout all the parts. The torque motor is symmetrically connected to two clamping nuts via two torsion coupling springs located at either end of the motor spindle. Two piezoelectric stacks can work independently to propel the opposing loads, which effectively take advantage of the anti-compression and non-tensile characteristics of piezoelectric element. The special feature of the actuator is the screw clamp mechanism, the operation of which involves intermittent rotation of two nuts (driven by the torque motor) on a feed-screw to achieve the bi-direction piezoelectric motion accumulation. Furthermore, the application of feed-screw could decrease the actuator’s sensitivity to wear, in order to realize a rigid self-locking and thus ensure the actuator’s holding capacity. A prototype was fabricated and the experimental results show that the no-load speed, maximum thrust, and peak power of the actuator were 20 mm/s, 280 N, and 1.54 W, respectively.
“The Paper Is White”: Examining Diversity Issues With the Next Generation of Journalists
Authors: Finneman Teri , Hendricks Marina A. , Bobkowski Piotr S.
Published: December 2021

Although the lack of diversity in newsrooms and reporting remains a serious issue in the journalism industry, college journalism education and student media provide a critical opportunity for change. Yet prior research has found notable diversity gaps in both. This study analyzed the state of diversity at a Midwestern university student newspaper and found significant gaps in coverage of diverse populations. The findings suggest the need for more comprehensive diversity education within the college classroom and campus media advising. This is important not only for more representative student media, but also for the future of journalism.
Bevacizumab-induced isolated oculomotor nerve palsy in glioblastoma multiforme
Authors: Değerli Ezgi , Alkan Gülin , Öztaş Nihan Şentürk , Bedir Şahin , Derin Sümeyra , Demirci Nebi Serkan
Published: December 2021

Introduction

Bevacizumab, a monoclonal antibody against the vascular endothelial growth factor receptor, is the standard treatment of recurrent glioblastoma multiforme. In addition to common systemic side effects of bevacizumab, there are rare cases of cranial nerve palsy.

Case report

We report a case of transient oculomotor nerve palsy after systemic administration of bevacizumab. Twenty-four hours after the systemic infusion of bevacizumab, transient oculomotor nerve palsy developed in a 49-year-old male patient. In the cranial MRI, there was no malignancy-related progression.

Management and outcome

Bevacizumab treatment was discontinued. Methylprednisolone was started considering that bevacizumab increased the inflammatory response. Oculomotor nerve palsy resolved in 14 days.

Discussion

There are many side effects of bevacizumab whose mechanisms of action have not been fully explained. Cranial nerve involvement is rarely reported. Our case is the first reported case of bevacizumab-induced oculomotor nerve palsy.
Problems with the MetaBLIND study: An examination of data on blinding patients in trials with patient-reported outcomes
Authors: Tack Michiel
Published: December 2021

MetaBLIND is the largest meta-epidemiological study on the impact of blinding in randomized trials to date. We examined MetaBLIND data on the impact of blinding patients on patient-reported outcomes. 68 out of 132 included trials tested knowledge recall and had questionable relevance to clinical trials. In 17 out of 18 comparisons, the number of trials in the blinded or nonblinded group was 2 or lower. In several key trials, the blinding status was uncertain. Effect sizes compared in MetaBLIND appear to reflect random differences in study design and setting rather than the impact of blinding trial participants.
Disciplinary differences in the study of the relationship between social variables and mental health: A systematic mapping review
Authors: Cruwys Tegan , Brossard Baptiste , Zhou Haochen , Helleren-Simpson Gabriel , Klik Kathleen A , Van Rooy Dirk , Batterham Philip J , Calear Alison L
Published: December 2021

There has been sustained interest in the intersection between social constructs and mental health from diverse disciplines including psychiatry, sociology and public health. However, no systematic attempt has been made to catalogue what is meant by ‘social’ by different researchers, how variables deemed ‘social’ constructs are linked to mental health, nor whether these patterns differ by academic discipline. Understanding interdisciplinary differences and commonalities may reveal opportunities for interdisciplinary collaboration to enhance our understanding of how social factors relate to mental health. This article presents a prospectively registered systematic map of social approaches to mental health using an innovative synthesis methodology (coding all sentences from a random selection of N = 287 articles). Results indicated that although approaches are diverse, disciplinary overlap is substantial. Psychology and psychiatry led articles tend to focus on social skills or emotions as features of mental (ill-)health, while public health and social sciences led articles tend to focus on social relationships, status or context as determinants of mental (ill-)health. Medicine led articles were most likely to focus on social outcomes of mental (ill-)health. Potential growth areas are noted, particularly the relative dearth of intervention research drawing upon social approaches. The findings are discussed with a view towards enabling more effective interdisciplinary collaboration.
The owners of information: Content curation practices of middle-level gatekeepers in political Facebook groups
Authors: Malinen Sanna
Published: December 2021

Volunteer moderators play a key role when making judgements about which online content should be accepted and which should be removed. As such, their work fundamentally shapes the digital social and political spheres. Using the data obtained from 15 Facebook group moderator interviews as research data, this study focused on the content curation work by the middle-level gatekeepers of Finnish political discussion groups on Facebook. The findings show that the moderators feel strong ownership of the groups they moderate and of the information such groups provide, and as a result, they strongly shape the groups’ discussion and governing policy. Facebook’s governing policy for groups is vague, which gives space for group norms and identities to develop. The stakeholder groups (i.e. the platform administration, moderators and users) do not attend to the governance process all together, so negotiations among them are almost non-existent.
Multivariate functional additive mixed models
Authors: Volkmann Alexander , Stöcker Almond , Scheipl Fabian , Greven Sonja
Published: December 2021

Multivariate functional data can be intrinsically multivariate like movement trajectories in 2D or complementary such as precipitation, temperature and wind speeds over time at a given weather station. We propose a multivariate functional additive mixed model (multiFAMM) and show its application to both data situations using examples from sports science (movement trajectories of snooker players) and phonetic science (acoustic signals and articulation of consonants). The approach includes linear and nonlinear covariate effects and models the dependency structure between the dimensions of the responses using multivariate functional principal component analysis. Multivariate functional random intercepts capture both the auto-correlation within a given function and cross-correlations between the multivariate functional dimensions. They also allow us to model between-function correlations as induced by, for example, repeated measurements or crossed study designs. Modelling the dependency structure between the dimensions can generate additional insight into the properties of the multivariate functional process, improves the estimation of random effects, and yields corrected confidence bands for covariate effects. Extensive simulation studies indicate that a multivariate modelling approach is more parsimonious than fitting independent univariate models to the data while maintaining or improving model fit.
The Role of Negative Pressure Wound Therapy (NPWT) in the Management of Vasculitic Wounds: Case Series of Eight Patients
Authors: Isoherranen Kirsi , Kluger Nicolas , Hannula-Jouppi Katariina , Väkevä Liisa
Published: December 2021

Vasculitic ulcers belong to the category of atypical ulcers and are traditionally very slow to heal. The aim of this study is to retrospectively analyze the files of eight patients with vasculitic ulcers treated with negative pressure wound therapy (NPWT). Immunosuppression was initiated at least two weeks prior to starting NPWT. We suggest that this is a safe and promising protocol to treat these hard-to-heal ulcers.
Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass
Authors: Jia Tong , Xing Zhen , Wang and Huijuan , Li Guoli
Published: December 2021

Cardiopulmonary bypass can result in damage to the intestines, leading to the occurrence of systemic inflammatory response syndrome. Dexmedetomidine is reported to confer anti-inflammatory properties. Here, the purpose of this study is to investigate the effect of dexmedetomidine on the intestinal mucosa barrier damage in a rat model of cardiopulmonary bypass. It was observed that cardiopulmonary bypass greatly decreased the levels of hemodynamic parameters than SHAM group, whereas dexmedetomidine pretreatment in a cardiopulmonary bypass model rat prevented this reduction. Also, it showed that compared with control animals, cardiopulmonary bypass caused obvious mucosal damage, which was attenuated in dexmedetomidine + cardiopulmonary bypass group. The above findings were in line with that of dexmedetomidine pretreatment, which increased the expression of tight junction proteins, but it decreased the levels of DAO, D-LA, FABP2, and endotoxin. Moreover, the results demonstrated that due to pre-administration of dexmedetomidine, the level of pro-inflammatory factors was decreased, while the level of anti-inflammatory cytokine was increased. Also, it showed that dexmedetomidine suppressed TLR4/JAK2/STAT3 pathway that was activated by cardiopulmonary bypass. Together, these results revealed that dexmedetomidine pretreatment relieves intestinal microcirculation, attenuates intestinal damage, and inhibits the inflammatory response of cardiopulmonary bypass model rats, demonstrating that in CPB-induced damage of intestinal mucosal barrier function, dexmedetomidine pretreatment plays a protective role by inactivating TLR4/JAK2/STAT3-mediated inflammatory pathway.
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions
Authors: Yao Xincheng , Son Taeyoon , Ma Jiechao
Published: December 2021

A portable, low cost, widefield fundus camera is essential for developing affordable teleophthalmology. However, conventional trans-pupillary illumination used in traditional fundus cameras limits the field of view (FOV) in a snapshot image, and frequently requires pharmacologically pupillary dilation for reliable examination of eye conditions. This minireview summarizes recent developments in alternative illumination approaches for widefield fundus photography. Miniaturized indirect illumination has been used to enable compact design for developing low cost, portable, widefield fundus camera. Contact mode trans-pars-planar illumination has been validated for ultra-widefield fundus imaging of infant eyes. Contact-free trans-pars-planar illumination has been explored for widefield imaging of adult eyes. Trans-palpebral illumination has been also demonstrated in a smartphone-based widefield fundus imager to foster affordable teleophthalmology.
Guns in the Hills: Firearms Circulation along the North-East Frontier of British India, 1860s–1910s
Authors: Dzüvichü Lipokmar
Published: December 2021

This article seeks to examine the significance of firearms in the making of the frontier and the ways in which societies on the North-East Frontier of British India encountered and adapted firearms between the 1860s and 1910s. It will study the complex ways in which the entry of firearms was mediated and galvanised by a range of processes such as imperial expansion, the intrusion of capital, access to resources, the role of violence, and the drawing of new borders. In turn, the circulation and diffusion of firearms also engendered a range of other practices and experiences among the societies on the frontier. Moving along various land and river routes, a range of individuals and traders were involved in circulating arms and ammunition into the imperial margins. They, in turn, linked the frontier geographies to markets, ports, and other larger oceanic networks. A focus on the flow of firearms as such illustrates a web of interconnections that straddled multiple scales and relations. As firearms circulated and gradually made their way into the periphery, various measures were initiated by the colonial state, such as enforcing prohibitive laws and instituting surveillance structures to control and block the flow of firearms along the North-East Frontier. This article examines some of these complex processes, dynamics, and experiences that ensued through the circulation and diffusion of firearms on the North-East Frontier of British India.
Banning the sale of modern firearms in Africa: On the origins of the Brussels Conference Act of 1890
Authors: Brahm Felix
Published: December 2021

The Brussels Anti-Slavery Conference in 1889–1890 agreed upon a sales ban of modern firearms for large parts of the African continent, a covenant that served joint imperial interests amid the ‘Scramble for Africa’. This article reconstructs the historical context in which the Brussels provisions came into being and explores the inter-imperial co-operation that paved the way for the agreement. To understand its origins, special attention must be paid to local events in East Africa and to a naval blockade that was executed here in 1888–1889. It was against this background that the German government, navigating between commercial and security interests, drafted the international control scheme that was later in large part adopted by the Brussels Conference. The article also demonstrates how in this context the issue of arms control was bound up with anti-slavery politics, thereby linking it to the imperial ‘civilising mission’.
Imperial legality through ‘Exception’: Gun control in the Russian Empire
Authors: Borisova Tatiana
Published: December 2021

Several days after a failed assassination attempt on the life of the Russian Tsar on 2 April 1879, a new regime of ‘permission to exercise the right to purchase and carry weapons’ was introduced in St. Petersburg. Despite the fact that the first attempt on Alexander II's life occurred in 1866 (also in St. Petersburg), it took 13 years to make a radical departure from the previously unrestricted regime of access to arms in the capital of the Russian Empire. In this article, I analyse archival materials documenting how this new regime of weapons ownership was implemented. In particular, I am interested in the dimensions of locality and temporality in the practices by which imperial legislation introduced gun control in St. Petersburg and Warsaw, the Russian Empire's most cosmopolitan cities. The archival documents that I rely on show that the gun control regulations that were intended to be a repressive act of the authorities in reality unfolded as a process of negotiations and merciful exclusions. The intermediaries of the imperial legal order reacted to the international challenges that were posed by emergent revolutionary movements, including the negotiation of the permissible restriction of subjects’ rights. As a result, new practices of ‘public safety’ were implemented as exceptional measures – both locally and temporally. This article sheds light on the imperial legal regime of gun control as a practice of ‘exception’.
Early-onset delirium after spontaneous intracerebral hemorrhage
Authors: Marrama Federico , Kyheng Maéva , Pasi Marco , Pierre Rutgers Matthieu , Moulin Solène , Diomedi Marina , Leys Didier , Cordonnier Charlotte , Hénon Hilde , Casolla Barbara
Published: December 2021

Objective

This study aimed at identifying the incidence, predictors, and impact on long-term mortality and dementia of early-onset delirium in a cohort of patients with spontaneous intracerebral hemorrhage.

Methods

We prospectively recruited consecutive patients in the Prognosis of InTra-Cerebral Hemorrhage (PITCH) cohort and analyzed incidence rate of early-onset delirium (i.e. during the first seven days after intracerebral hemorrhage onset) with a competing risk model. We used a multivariable Fine-Gray model to identify baseline predictors, a Cox regression model to study its impact on the long-term mortality risk, and a Fine-Gray model adjusted for pre-specified confounders to analyze its impact on new-onset dementia.

Results

The study population consisted of 248 patients (mean age 70 years, 54% males). Early-onset delirium incidence rate was 29.8% (95% confidence interval (CI) 24.3–35.6). Multivariate analysis showed that pre-existing dementia (subhazard ratio (SHR) 2.08, 95%CI 1.32–3.32, p = 0.002), heavy alcohol intake (SHR 1.79, 95%CI 1.13–2.82, p = 0.013), and intracerebral hemorrhage lobar location (SHR 1.56, 95%CI 1.01–2.42, p = 0.049) independently predicted early-onset delirium. Median follow-up was 9.5 years. Early-onset delirium was associated with higher mortality rates during the first five years of follow-up (HR 1.52, 95%CI 1.00–2.31, p = 0.049), but did not predict new-onset dementia (SHR 1.31, 95%CI 0.60–2.87).

Conclusion

Early-onset delirium is a frequent complication after intracerebral hemorrhage; it is associated with markers of pre-existing brain vulnerability and with higher mortality risk, but not with higher dementia rates during long-term follow-up.
Psychological profiles in adults with knee OA-related pain: a replication study
Authors: Johnson Alisa J. , Laffitte Nodarse Chavier , Peraza Julio A. , Valdes-Hernandez Pedro A. , Montesino-Goicolea Soamy , Huo Zhiguang , Fillingim Roger B. , Cruz-Almeida Yenisel
Published: December 2021

Introduction:

Psychological factors have been associated with knee osteoarthritis pain severity and treatment outcomes, yet their combined contribution to phenotypic heterogeneity is poorly understood. In particular, empirically derived psychological profiles must be replicated before they can be targeted or considered for treatment studies. The objectives of this study were to (1) confirm previously identified psychological profiles using unsupervised clustering methods in persons with knee osteoarthritis pain, (2) determine the replicability of profiles using supervised machine learning in a different sample, and (3) examine associations with clinical pain, brain structure, and experimental pain.

Methods:

Participants included two cohorts of individuals with knee osteoarthritis pain recruited as part of the multisite UPLOAD1 ( n = 270, mean age = 56.8 ± 7.6, male = 37%) and UPLOAD2 ( n = 164, mean age = 57.73 ± 7.8, male = 36%) studies. Similar psychological constructs (e.g. optimism, coping, somatization, affect, depression, and anxiety), sociodemographic and clinical characteristics, and somatosensory function were assessed across samples. UPLOAD2 participants also completed brain magnetic resonance imaging. Unsupervised hierarchical clustering analysis was first conducted in UPLOAD1 data to derive clusters, followed by supervised linear discriminative analysis to predict group membership in UPLOAD2 data. Associations among cluster membership and clinical variables were assessed, controlling for age, sex, education, ethnicity/race, study site, and number of pain sites.

Results:

Four distinct profiles emerged in UPLOAD1 and were replicated in UPLOAD2. Identified psychological profiles were associated with psychological variables ( ps < 0.001), and clinical outcomes ( ps = 0.001–0.03), indicating good internal and external validation of the cluster solution. Significant associations between psychological profiles and somatosensory function and brain structure were also found.

Conclusions:

This study highlights the importance of considering the biopsychosocial model in knee osteoarthritis pain assessment and treatment.
Preparing preservice early childhood educators to use music in Australian settings: An audit of programmes
Authors: Pestana Ginette
Published: December 2021

Music is ever-present in early childhood but does not feature strongly in the national curriculum framework – The Early Years Learning Framework in Australia or in the intentional practice of educators in early childhood education and care settings. This is mainly due to a lack of knowledge and confidence or self-efficacy to engage musically with the children. Preservice educator training plays a critical role in the development of effective pedagogical skills, knowledge and understanding. This article explored the music education preparation that preservice educators receive in initial training. A content analysis approach was used to review course content of all approved preservice educator programmes in Australia by the Australian Children’s Education & Care Quality Authority. Interviews with tertiary teachers explored content taught. The findings offer rich insight into the extent of music education provided for preservice early childhood educators and implications for the development for future programmes.
Pleomorphic adenoma in the external auditory canal: Arising at an atypical location
Authors: Dongol Kripa , Karki Utsav Raj
Published: December 2021

Pleomorphic adenoma is a common, benign neoplasm typically located in the major salivary glands. The external auditory canal is an atypical location for a pleomorphic adenoma to originate. Wide surgical excision is essential in cases of pleomorphic adenoma due to its tendency to recur and change into malignancy. We report a case of pleomorphic adenoma emerging in the external auditory canal, which is an atypical location for it to originate. A 23-year-old male presented with swelling and decreased hearing in the left ear for 2 months. On examination, there was a smooth, pink, firm swelling in the cartilaginous part of external auditory canal. Pure tone audiogram and computed tomography of temporal bone were performed. The patient underwent excision biopsy and the diagnosis of pleomorphic adenoma was confirmed after histopathology. Long-term follow-up is recommended as pleomorphic adenoma has the potentiality to recur or transform into malignancy.
Contemporary standards in UK nephrectomy practice: Analysis of the British Association of Urological Surgeons Complex Operations Reports, 2016–2018
Authors: Pascoe John , John Joseph , Fowler Sarah , Narahari Krishna , Challacombe Ben , Dickinson Andrew , McGrath John S
Published: December 2021

Objective:

To analyse the 2016–2018 British Association of Urological Surgeons (BAUS) Complex Operations Reports nephrectomy database, providing a comprehensive description of modern nephrectomy practice.

Patients and Methods:

Analysis of 2016–2018 data held on the BAUS Complex Operations Reports nephrectomy database was performed for 21,366 patients in England. Data are reported on patient, disease, operation and outcome variables.

Results:

Using Hospital Episode Statistics (HES) as a comparator, the database captured an estimated 88% of nephrectomies. Benign nephrectomies (BNs) accounted for 11%, 51% were radical nephrectomies (RNs), 14% were nephroureterectomies (NUs) and 22% were partial nephrectomies (PNs). Of the 2399 BNs, 10% were performed for stone disease, 9% for allograft donation and 9% for infective pathology. Aetiology was not specified further than non-functioning kidney in 51% of cases; 80% of cases adopted minimally invasive surgery (MIS). Histology was benign in 96% of cases. Of 10,843 RNs performed, 77% were performed using MIS. Final histology was renal cell carcinoma in 87% of cases and benign histology confirmed in 9% of cases. Of 3038 NUs performed, 88% were performed using MIS. Histology confirmed malignancy in 94% of cases with transitional cell carcinoma accounting for 82% of cases overall. Of 4708 PNs performed, 74% were performed using MIS; 85% of cases were performed for T1 disease; 16% of cases overall returned benign histology. Across the cohort, 30-day mortality was 0.36%. Transfusion rates were 3.3%, 6.1%, 3.3% and 2.0% for BNs, RNs, NUs and PNs, respectively. In malignant disease, positive surgical margins were present in 0.7% of RNs, 1.2% of NUs and 7.3% of PNs.

Conclusions:

The BAUS nephrectomy dataset provides a real-world description of nephrectomy practice across England, enabling surgeons to compare their practice against a national average. This dataset allows surgeons to share data with patients enhancing informed consent and facilitating shared-decision making. Overall, MIS is widespread, and early mortality after nephrectomy is low.

Level of evidence:

2B
“Consent Is F#@king Required”: Hashtag Feminism Surrounding Sexual Consent in a Culture of Postfeminist Contradictions
Authors: Kettrey Heather Hensman , Davis Alyssa J. , Liberman Jessica
Published: December 2021

Hashtag feminism exists in a time of postfeminist contradictions marked by the simultaneous existence of popular feminism and popular misogyny. In one such contradiction, popular feminism has led women to expect the successful negotiation of sexual consent, while popular misogyny permits the circulation of traditional sexual scripts that disregard the necessity of consent. In this study, we analyze messages conveyed through digitized narratives of sexual consent posted on Tumblr, a social media site that is popular among feminist activists, to identify the ways that users construct meaning around the dissonance between expectations for consent and the inequalities that inhibit its negotiation. We specifically explore whether hashtag feminism navigates postfeminist contradictions in a way that simultaneously calls out misogyny and calls on feminism. We find that the Tumblr posts in our sample did both, albeit in a manner that failed to offer tangible solutions to the problem at hand. Calls on feminism were largely limited to tagging feminist allies and recirculating existing feminist campaigns. Thus, we argue that the hashtag ultimately became a handoff to a larger feminist abstraction. Future research should explore conditions under which activists link tangible issues, actors, and agendas to an otherwise abstract popular feminism.
The Effects of “Live,” Authentic, and Emotional Instagram Images on Congressional Candidate Evaluations
Authors: Zulli Diana , Towner Terri L.
Published: December 2021

This study examines how Instagram’s design and norms influence expectations for political imagery and, subsequently, the effects of these images on electability, vote likelihood, and candidate evaluations. Using the Elaboration Likelihood Model, we propose three norms of Instagram that likely function as heuristic cues and affect the reception of political visual communication on the platform: liveness, authenticity, and emotionality. We experimentally test these visual features on Congressional candidate images, finding some evidence that live, authentic, and emotional images positively influence vote likelihood but negatively impact electability. Results also indicate that live, authentic, and emotional images either have no or negative effects on female candidate evaluations or have no or positive effects on male candidate evaluations.
Older age and varus alignment lead to early failure in treating patellofemoral osteoarthritis with Fulkerson osteotomy
Authors: Yang Cheng-Pang , Chang Chun-Hao , Weng Chun-Jui , Hung Kung-Tseng , Chen Alvin Chao-Yu , Hsu Kuo-Yao , Chan Yi-Sheng
Published: December 2021

Background: It is unclear the risk factors for the failure of modified Fulkerson osteotomy. Methods: We retrospectively reviewed 40 patients who underwent the modified Fulkerson osteotomy from 1998 to 2015. There were 4 males and 36 females. The mean age of the study group was 50.2 ± 11.2 years. We used standard anteriorization measuring 10–15 mm and medialization measuring 10 mm while maintaining an intact periosteal sleeve. Results: Both the patellofemoral angle and the congruence angle improved significantly after 5.9 years. Preoperatively, the mean preoperative Lysholm score was 56.12, and the Knee Society score was 60.52. At the final follow-up, these scores improved significantly to 88.75 and 86.49, respectively. However, eight patients (20%) underwent total knee arthroplasty in the follow-up period, five of whom underwent the operation within 5 years. Comparing the survival and non-survival groups, there was a significant difference of an older age in the TKA conversion group (survival: 48.3 ± 11.1; non-survival: 57.8 ± 8.7, p = 0.03). For knee alignment, the non-survival group had a mean valgus femorotibial angle of 1.8° ± 4.9° preoperatively, and the survival group had a mean valgus angle of 6.4° ± 4.5° ( p = 0.03). Conclusions: we found that patients with older age and those with varus alignment have an increased risk of deteriorated medial femorotibial cartilage.