bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Perubahan Parameter Fisik-Kimia terhadap Aktivitas Mikroorganisme selama Proses Pengomposan Sampah Organik Kantin
Authors: Banaget Cut Keumala , Kristanto Gabriel S. Boedi Andari , Danumihardja Irma Gusniani
Published: February 2020

Pengolahan sampah sisa makanan perlu menjadi prioritas karena jumlahnya yang besar serta sifatnya yang mudah membusuk dan memicu kehadiran hewan pembawa penyakit seperti tikus.Salah satu teknik pengolahannya adalah pengomposan, yaitu proses degradasi sampah organik oleh mikroorganisme menjadi material sejenis humus yang dapat dimanfaatkan. Tujuan penelitian ini adalah untuk menganalisis faktor-faktor (meliputi parameter fisik-kimia) yang mempengaruhi proses pengomposan, serta menganalisis hubungan dan pengaruh faktor tersebut terhadap aktivitas mikroorganisme selama proses pengomposan berlangsung. Analisis statistik dalam penelitian ini meliputi analisis faktor, korelasi, dan multivariabel. Berdasarkan analisis faktor yang dilakukan,terbentuk 2 faktor baru yang mempengaruhi proses pengomposan, yaitu faktor 1 dinamakan parameter yang menunjukkan hasil dari proses pengomposan, terdiri dari konduktivitas, salinitas, dan kadar air; dan faktor 2 dinamakan parameter yang mendukung proses pengomposan, terdiri dari rasio C/N, kadar karbon, pH, dan kadar nitrogen. Hasil analisis korelasi menunjukkan kadar air, rasio C/N, kadar karbon, pH, kadar nitrogen memiliki pengaruh terhadap aktivitas mikroorganisme. Berdasarkan analisis multivariabel, komposter 2 diperkirakan memiliki model regresi pengaruh faktor pengomposan terhadap aktivitas mikroorganisme yang terbaik. Sedangkan dilihat dari penurunan kadar karbonnya, komposter 1 memiliki konstanta laju pengomposan dan laju dekomposisiterbesar dibandingkan dua komposter lainnya, yaitu sebesar 0,0006 dan 0,0224%/hari.
Analysis of Loading Change Effect to Boat Velocity on a 2.5GT Fishing FRP Boat with a Field Test
Authors: Klara Syerly , Mahmuddin Faisal , Muas Muhammad
Published: February 2020

In order to determine the effect of load change to ship velocity on a 2.5 GT fishing boat, a field test is conducted in the present study. The boat model used in the field test is an actual size boat made from fiber reinforced plastic (FRP) material. The boat is powered by 2 (two) 15 HP direct drive engines each equipped with 3-bladed single screw propeller. Two loading cases are investigated and analyzed which are no load case and with load case. For each case, 4 (four) engine power variations are performed which are 25%, 50%, 75% and 100%. The main parameters measured are boat draught, engine power percentage, shaft revolution speed and boat velocity. From the field test, it is found that even though the propulsion performance increases larger loading and displacement, the increased boat resistance due to larger wetted surface make the boat velocity reduces.
Rancang Bangun Alat Pendeteksi Kondisi Cuaca Kota Balikpapan Menggunakan Global Navigation Satellite System (GNSS) Wind Turbine
Authors: Endrawati Budiani Fitria , Yusphie Adhe , Putri Arum Prastiyo , A Azam Fadhil , R Mohammad Saiful , Robiandi Fadli
Published: February 2020

Balikpapan is one of the cities in East Kalimantan with unique characteristic of the region. The characteristics of the region and the height of the area from the sea surface of the city of Balikpapan is one of the factors, therefore need to be designed a tool to detect weather especially in Balikpapan city. The device design using Global Navigation Satellite System (GNSS) Wind Turbine. The measurement results are based on temperature, humidity and wind speed. From the measurement of temperature, humidity and wind speed obtained an average of 30.97oC; 73.49% and 2.91 m/s. According to method World Meteorological Organization, temperature, humidity and wind speed data is accepted.
Evaluasi Kesuksesan SICANTIK Menggunakan Information Systsem Succes Model (ISSM)
Authors: Lois Gianda Almyra , Fadli Anang Syaifuddin N , Renaldi Michael , Santoso Muthi’ah Rahmayanti , Wiranti Yuyun Tri
Published: February 2020

Saat ini, Information and Communication Technology (ICT) atau teknologi komunikasi dan informasimerupakan sesuatu yang sudah menjadi bagian yang tidak terpisahkan dari kehidupan manusia, terutama merekayang hidup di kota besar. Teknologi komunikasi dan informasi sudah menjadi sebuah kebutuhan, salah satunyaadalah kebutuhan dihargai dan dipandang dalam kerja maupun kehidupan sehari-hari pada umumnya.Ketersediaannya juga sudah mencapai pada hal-hal yang paling rumit dan sederhana dari pengiriman,penyimpanan, pengolahan dan pengiriman data dengan kemampuan jangkauan yang sangat luas. DinasPenanaman Modal dan Perizinan Terpadu (DPMPT) Kota Balikpapan adalah salah satu instansi pemerintahanyang telah menerapkan teknologi sebagai pendukung layanan dalam proses bisnisnya salah satunya adalahdibuatnya SiCantik. Belum adanya pengukuran kinerja dan evaluasi penerapan teknologi informasi padaSiCantik dan untuk membantu DPMPT mengevaluasi serta mengembangkan teknologi informasi yangdigunakan, menjadi latar belakang dilakukannya penelitian pada Sistem divisi IT di DPMPT Kota Balikpapan.Beberapa kesimpulan yang ditemukan yaitu, telah dilakukannya Evaluasi Kesuksesan SiCantik menggunakanInformation Systems Success Model (ISSM), dan didapatkan hasil wawancara dengan pihak DPMPT sertapengolahan data evaluasi dengan menggunakan metode penyebaran kuesioner dengan jumlah respondensebanyak 47 responden yang merupakan user dari SiCantik, terdiri dari 17 pegawai DPMPT dan 30 pengunjungDPMPT. Setelah melakukan pengolahan data, didapatkan 4 usulan strategi untuk masing-masing variabel.
KONSEP WISATA BUDAYA KALIJA KELURAHAN TASIKMADU KECAMATAN LOWOKWARU KOTA MALANG
Authors: Reza Mohammad , Budi Santosa Endratno , Poerwati Titik
Published: February 2020

Industri pariwisata pada umumnya memberi peran penting bagi perekonomiandaerah karena dapat memberikan tambahan Pendapatan Asli Daerah sehinggapenerimaan daerah meningkat, selain itu dapat menambah lapangan pekerjaanbagi masyarakat di sekitar tempat wisata, dimana potensi pariwisata tersebutdapat di kelola oleh penduduk setempat.Tujuan dari penelitian ini yaitu untuk mengetahui konsep Wisata Budaya Kalija(Kalimantan Jawa) di Kelurahan Tasikmadu Kecamatan Lowokwaru KotaMalang. Metode analisa dalam penelitian ini menggunakan metode kualitatifdan berdasarkan kondisi eksisting dari lokasi penelitian. Wisata Kalijamerupakan tempat wisata degan konsep budaya tradisional. Konsep wisata inimenyajikan objek wisata yang berbeda dibandingkan dengan objek-objekwisata lain yang ada di lingkup Malang Raya. Wisata Kalija akan menampilkanpentas budaya setiap harinya, secara bergantian antara Kalimantan dan Jawa.Wisata ini dibuat semenarik mungkin dan dapat membuat pengunjung merasaseakan berada di Kota Kalimantan maupun di Jawa.
RUANG TEMPORER SOSIAL SEBAGAI SALAH SATU BENTUK RUANG SOSIAL DAN ASPIRASI MASYARAKAT DALAM PEMENUHAN KEBUTUHAN RUANG PUBLIK KOTA
Authors: Adi Putrag Ghoustanjiwani , Triwahyono Daim
Published: February 2020

Ruang temporer sosial dipahami sebagai ruang publik yang terbentuk dariproses sosial. Dalam (Lefebvre 2000) “production of space” ruang sosoaldigambarkan kedalam bentuk ruang yang terstruktur dari waktu (Time).Pada studi kasus terpilih yaitu: Festival kampung sedjarah Tawangsari,penulis melakukan kajian evaluasi secara deskriptif dari kajian literatur danhasil penelitian terkait. Penulis menemukan bahwa ruang sosial temporerpada studi kasus dipengaruhi oleh 3 faktor jaringan pembentuk antara lain:Ikatan Antar aktor pembentuk yang simetris, ikatan antar individu aktor padajaringan masyarakat yang lebih luas dan adanya struktur ikatan sosial yangterhubung .
Serviceability and post-failure behaviour of laminated glass structural elements
Authors: Piscitelli Lorenzo Ruggero
Published: February 2020

Glass structures are being built ever more frequently all over the world, in a growing architectural trend towards light, transparency and sustainability. The engineering design of laminated glass elements being profoundly influenced by properties of interlayers, this multi-scale research highlights some among the key elements on the hyperelastic and viscoplastic response of such synthetic materials. Results and new discoveries are interpreted to better model and predict the response of laminated glass structures: examples are provided for design applications to post-failure safety assessments, structural design and cold-bending techniques. Still, in a vastly unknown field, a growing market and foggy regulatory framework, many challenges and research opportunities remain to be dealt with.
Correlation dynamics of transpiration intensity of pinus nigra subsp. Pallasiana with photosynthesis, temperature of needles and some environmental factors during vegetation under the conditions of the southern coast of the Crimea
Authors: Ilnitsky O. A. , Plugatar Yu. V.
Published: February 2020

The relationship dynamics of the intensity of transpiration of Pinus nigra subsp. pallasiana with photosynthesis, pine needles temperature and some environmental factors in the process of active plant growth in the Southern Coast of the Crimea was examined. The display function response of transpiration to environmental factors allowed to determine the optima of these dependencies, and to obtain numerical coefficients of nonlinear regression equations for their correlations. During the period of active growth of the plant (June and September), the intensity of transpiration and the studied environmental factors changed: transpiration intensity - by 53.34%, air temperature - by 17.86%, air humidity level - by 42.86% and illumination - by 35.72%. Critical value of optimal temperature of phytosynthesis and transpiration. P. nigra subsp. pallasiana has a high potential for acclimatization at elevated ambient temperatures. The critical temperature of pine needles for this species is 38°C. The relative speed of xylary flow in the plant shoot and changes in its diameter combine the indicators of available moisture in the soil for the plant and the parameters of the environment. The data obtained allow us to interpret the intensity of transpiration as a potential ecological and physiological characteristic of this species. There is an opportunity to compare the results of our research with known from literary sources for the various species and subspecies of pines growing in similar climatic conditions using identical techniques.
KESADARAN MASYARAKAT TERHADAP HUKUM PERKAWINAN DALAM PENERAPAN UNDANG-UNDANG NO 1 TAHUN 1974 TENTANG PERKAWINAN (Studi Deskriptif pada Masyarakat Kelurahan Gombengsari Kecamatan Kalipuro Banyuwangi)
Authors: Zulfa Mardiyatus Sholeha  , Harjianto
Published: February 2020

Perkawinan di bawah umur adalah perkawinan yang dilakukan oleh seorang pria dan seorang wanita yang usia keduanya masih di bawah batasan minimum yang diatur oleh Undang-undang. Meskipun telah dijelaskan batas usia anak dapat melangsungkan perkawinan sesuai dengan Undang-undang perkawinan, masih banyak orang tua di pedesaan yang menikahkan anak perempuan pada usia 14-16 tahun.Tujuan dari penelitian ini adalah untuk mengetahuipemahaman masyarakat terhadap aturan dan hukum perkawinan yang sudah berkembang di masyarakat.

Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan pendekatan studi kasus. Data lapangan diperoleh dengan teknik observasi dan wawancara. Analisis data menggunakan analisis kualitatif, yaitu analisis yang memberikan deskripsi mendalam dan kesimpulan yang sesuai dengan topik dan tujuan dari penelitian. Adapun tahapan analisis data adalah tahap reduksi data, tahap penyajian data dan tahap analisis data. Hasil Penelitian ini menunjukan bahwa latar belakang masyarakat melakukan perkawinan di bawah umur yang terjadi di kelurahan gombengsari disebabkan oleh beberapa  faktor diantaranya 1). Faktor ekonomi, 2). Faktor pendidikan, 3). Faktor orang tua, 4). Faktor lingkungan. Dari hasil penelitian juga menunjukan adanya dampak dari perkawinan di bawah umur diantaranya yaitu dampak positif, dampak negatif dan dampak terhadap hukum.
PERBEDAAN PEMASANGAN KATETER DENGAN MENGGUNAKAN JELLY YANG DIMASUKKAN URETRA DAN JELLYYANG DIOLESKAN DI KATETER TERHADAP TINGKAT NYERI PASIEN DI RSUD SELE BE SOLU KOTA SORONG
Authors: Mobalen Oktovina , Tansar Tansar , Maryen Yehud
Published: February 2020

Eliminasi merupakan salah satu pemenuhan kebutuhan fisologis manusia. Terganggunya eliminasi menandakan terjadinya gangguan pada bagian sistem perkemihan sehingga menimbulkan ketidaknyamanan dalam kehidupan sehari – hari dan dapat mengganggu aktivitas.Pemasangan kateter urin merupakan suatu tindakan invasif dengan memasukkan selang ke dalam kandung kemih yang mana bertujuan untuk membantu dalam mengeluarkan urin.Tindakan ini dapat menyelamatkan kehidupan, khususnya bila saluran kemih tersumbat atau pasien tidak dapat melakukan pengeluaran urin. Penelitian ini dilakukan untuk mengetahui perbandingan respon nyeri pada prosedur kateterisasi urin pria dengan teknik pengolesan jelly pada kateter dan penyemprotan jelly langsung ke dalam urethra. Jenis penelitian adalah eksperimen dengan desain quasi eksperimen. Jumlah sampel 30 responden yang dilakukan dengan kuota sampling.Analisa penelitian ini menggunakan uji mann-whitney, hasil penelitian menunjukkan ada perbedaan  yang bermakna antara jelly yang dimasukan diuretra dan jelly yang dioleskan di kateter terhadap tingkat nyeri pasien.
$2$-Neighbour-Transitive Codes with Small Blocks of Imprimitivity
Authors: Gillespie Neil I. , Hawtin Daniel R. , Praeger Cheryl E.
Published: February 2020

A code $C$ in the Hamming graph $\varGamma=H(m,q)$ is $2$-neighbour-transitive if ${\rm Aut}(C)$ acts transitively on each of $C=C_0$, $C_1$ and $C_2$, the first three parts of the distance partition of $V\varGamma$ with respect to $C$. Previous classifications of families of $2$-neighbour-transitive codes leave only those with an affine action on the alphabet to be investigated. Here, $2$-neighbour-transitive codes with minimum distance at least $5$ and that contain ``small'' subcodes as blocks of imprimitivity are classified. When considering codes with minimum distance at least $5$, completely transitive codes are a proper subclass of $2$-neighbour-transitive codes. This leads, as a corollary of the main result, to a solution of a problem posed by Giudici in 1998 on completely transitive codes.
La tragedia educativa
Authors: Smith René Rogelio
Published: February 2020

Obra reseñada:

Jaim Echeverry, G. (1999). La tragedia educativa. Buenos Aires: Fondo de Cultura Económica.
Heart-Type Fatty Acid-Binding Protein (H-FABP) in Patients with Type 2 Diabetes Beneficiaries of Rehabilitation Program Post Coronary Artery Bypass Grafting
Authors: Namat Razan Al , Felea Maura Gabriela , Costache Irina Iuliana , Aursulesei Viviana , Petris Antoniu , Mitu Ovidiu , Constantin Mihai , Sorodoc Victorita , Sorodoc Laurentiu , Miftode Ionela Larisa , Miftode Radu , Namat Nadia Al , Namat Dina Al , Luta Andreea , Ion Adriana , Mihalcia Mirela Mihaela , Ciocoiu Manuela , Tinica Grigore , Mitu Florin
Published: February 2020

Heart-type fatty acid-binding protein (H-FABP) is a non-invasive bio-marker, with high sensitivity and specificity, being capable to point out the myocardial injury and to predict major adverse cardiovascular events (MACE). Cardiac rehabilitation program, through a complex and sustained post-interventional management plays an important role in reducing the plasma levels of H-FABP. In the study, which included 120 post-coronary artery bypass (CABG) patients, we analyzed the link between low levels of general post-surgical health status and the presence of cardiovascular risk factors, common biochemical markers, and especially the role played by diabetic status in lowering the plasma H-FABP levels. From the group, 65 patients had been diagnosed with type 2 Diabetes Mellitus (T2DM). The H-FABP values decreased both in diabetics and in non-diabetics between the two phases of CR, 6 months away from CABG. More than half of the patients had important reduction of H-FABP, at 6 months after the onset of CR program. Half of the group registered a smaller reduction of H-FABP, but more noticeable in diabetics. Ischemic lesion during open heart surgery is linked to high levels of H-FABP and with an occurence risk of postoperative atrial fibrillation, that can be also triggered and sustained by multiple endocrine conditions related to aging. Thus, metabolic control should always remain a target of the complex management in cardiac rehabilitation.
The Control of Bloodloss During Percutanerous Nephrolithotomy Using Tranexamic Acid
Authors: Barbilian Raluca Costina , Cauni Victor , Mihai Bogdan , Buraga Ioana , Dragutescu Mihai , Mischianu Dan
Published: February 2020

The aim of this study is to assess the efficiency and safety of the tranexamic acid in reducing hemmorrhagic complications and transfusion requirements in patients with renal lithiasis treated by percutaneous approach. Percutaneous nephrolithotomy (PCNL) is a minimally invasive technique used for large kidney stones (]20mm). Urinary sepsis and intra or postoperative bleeding are the very serious complications associated with this type of procedure. Tranexamic acid is used in the treatment of many haemorrhagic conditions. The experience with tranexamic acid in preventing bloodloss during percutaneous nephrolithotomy is very limited. The use tranexamic acid in percutaneous nephrolithotomy is safe and is associated with reduced blood loss and a lower transfusion rate.
Studies on Chromatographic Fractioning by Cations Exchangers of a Bovine Hemoglobin Hydrolysate
Authors: Panainte Alina Diana , Morariu Ionela Daniela , Bibire Nela , Vieriu Madalina , Tantaru Gladiola , Luca Alina Costina , Apostu Mihai
Published: February 2020

A peptidic hydrolysate has been obtained through hydrolysis of bovine hemoglobin using pepsin. The fractioning of the hydrolysate was performed on a column packed with CM-Sepharose Fast Flow. The hydrolysate and each fraction was filtered and then injected into a HPLC system equipped with a Vydak C4 reverse phase column (0.46 x 25 cm), suitable for the chromatographic separation of large peptides with 20 to 30 amino acids. The detection was done using mass spectrometry, and the retention time, size and distribution of the peptides were determined.
Lethal Helium Intoxication. Determining the Context, Cause and Time of Death
Authors: Scripcaru Andrei , Knieling Anton , Manea Cristiana , Crauciuc Dragos Valentin , David Sofia Mihaela , Sandu Ion , Bulgaru Iliescu Diana
Published: February 2020

Helium is the chemical element with atomic number 2, represented by the symbol He. It is an inert, colorless, odorless, insipid monoatomic gas. It has the lowest boiling point and the lowest melting point among the chemical elements and appears only in gaseous state, except for extreme conditions. The use of helium for suicidal purposes is extremely rare. In Romania, suicide has a frequency of 12 per 100,000 inhabitants, which classifies us in the category of countries with low suicide rates. As methods, men use hanging most often while women use more softer methods such as poisoning. Helium is rarely used for suicidal purposes because it is relatively difficult to obtain. Basically, it is not poisoning in the true sense of the word, but rather the substitution of oxygen with helium, which cannot be carried by hemoglobin, and thus transport asphyxia occurs. At the end of the paper we shall exemplify a case of helium poisoning for suicide purposes, purchased from a cylinder for inflating balloons.
The Role of Saline Aerosols in the Prevention and Therapy of Cardio-respiratory and Osteo-muscular Afflictions
Authors: Sandu Ioan Gabriel , Vasilache Viorica , Sandu Andrei Victor , Chirazi Marin , Honceriu Cezar , Dabija Radu Crisan , Vladescu Alina , Cotrut Cosmin Mihai , Sandu Ion
Published: February 2020

The saline aerosols generated in gaseous media, as nanodispersions, behave, with respect to the concentration levels and the lifespan, as trimodal distributions (the three domains with Gaussian distributions: fine or Aitken under 50 �m, medium between 50 and 500 mm and, respectively, coarse or large between 500 and 1000 mm). The generation in latent state is dependent on the active surface of the source (number of generator centres, the size and position of the fluorescences, the porosity, size and shape of the source, etc.), the climatic parameters, but also on a series of other characteristics of the gaseous medium. Our team has demonstrated experimentally that saline aerosols, NaCl type, besides the ability to prevent and treat broncho-respiratory and cardiac conditions, through coassistance of saline aerosols of other cations than sodium, and of the iodine anion, have for certain levels of concentrations propitious effects over the immune, bone and muscular systems. Similarly proved has been the positive influence on the development of children, as well the determinant role in increasing athletic performance and of other human subjects performing intense activities.
Chemical Anaplasia in Atypical Debut of Non-small Cell Lung Cancer with Inguinal and Obturator Lymph Node Metastases
Authors: Rebegea Laura , Nechita Aurel , Serban Cristina , Diaconu Camelia , Macovei Luana Andreea , Draganescu Miruna , Firescu Dorel
Published: February 2020

Non-small cell lung cancer (NSCLC) represents almost 80-85% of lung cancer cases. It is the most frequent malignancy after skin cancer. The therapeutic options for stage IV of disease consider histology, molecular characteristics, age, performance status, comorbidities, and not in the lust, patient�s option. This paper presents the case of a male patient, 73 years old, smoker, presented and treated in May 2016 in the Sf. Ap. Andrei Emergency Clinical Hospital Galati. The first sign of disease was inguinal and obturator right lymph node metastases whose histopathological test revealed metastases from malignant melanoma. Immunohistochemical tests (IHC) indicated undifferentiated carcinoma with lung as starting point, (Ck7 (+), TTF1 (+)). Thorax, abdominal and pelvic computed tomography (CT) imaging not evidenced space replacement processes in lung, but with mediastinal, right obturator and inguinal adenopathy. From personal pathological history we retain basocellular carcinoma in lumbar region, treated with surgery in 2009. It was initiated palliative chemotherapy and radiotherapy with remission of obturator and inguinal adenopathy, and at 9 months from diagnosis the Positron Emission Tomography (PET-CT) evidenced primary lung tumor situated in right superior lobe (RSL). At the present, patient is alive performing palliative chemotherapy. This case presented diagnostic and treatment issues, being a challenge for multidisciplinary team. We are mentioning the paucity of literature data regarding cases of primary tumors situated upper diaphragm which metastases in inguinal lymph nodes.
Osseointegration Evaluation of Two Socket Preservation Materials in Small Diameter Bone Cavities An in vivo lab rats study
Authors: Obadan Florin , Craitoiu Monica , Manolea Horia , Mogoanta Laurentiu , Osiac Eugen , Rica Radu , Salan Alex Ioan , Earar Kamel
Published: February 2020

The present study aims to evaluate the osseointegration in small diameter rat bone cavities of a collagen-based material and a synthetic bone graft by using a protocol consisting of three evaluation methods: direct macroscopic examination, optical coherence tomography (OCT) and a histological study. For this study we made three study groups, each of them consisting of twelve laboratory Whistar rats, one for each studied material and one control group. For each study group, six laboratory rats were sacrificed after two months, and the other six after four months in order to evaluate the bone wound healing.The total amount of augmentation was significantly greater in the augmented groups than in the control group. Macroscopic examination of the evolution of augmented bone wound healing with the collagen-based material offered spectacular results especially in the cavities prepared in the calvaria, while in the bone wounds augmented with OssceramNano we always noticed the presence of synthetic material residual particles. The OCT evaluation highlighted the degree of filling of the defect through the lack of refractivity of the collagen-based material, while the higher refractive index of the synthetic bone graft material allowed some spectacular observations. On the histological samples from the first study group, filled with the collagen-based material, we generally have observed the filling of the experimental bone defects with repairing connective tissue with various bone extensions from the surrounding bone tissue The histological assessment of the synthetic bone graft augmented cavities showed firstly the presence of synthetic material residual particles surrounded by a newly formed connective tissue in early stages or a young bone tissue with many osteoblasts in the advanced stages of osseointegration.
The Utility of Visceral Adiposity Index in Prediction of Metabolic Syndrome and Hypercholesterolemia
Authors: Socea Bogdan , Radu Lucretiu , Clenciu Diana , Tenea Cojan Tiberiu Stefanita , Baleanu Vlad , Ene Cristina Gabriela , Girgavu Sigina Rodica , Vladu Ionela Mihaela
Published: February 2020

Metabolic syndrome (MS) is defined as a complex entity that involves the accumulation of cardiovascular and metabolic risk factors represented by: abdominal obesity, insulin resistance, hypertension, dyslipidemia [1]. The presence of MS correlates with the risk of cardiovascular disease in people without diabetes mellitus (DM), as well as those with type 2 DM [2-8].Visceral adipose tissue is an active metabolic organ and abdominal obesity is an independent risk factor for metabolic disorder present in MS [9,10,11], associated with the development of cardiovascular disease and type 2 diabetes in children, adolescents and adults [12-15]. Our findings have shown an association of visceral adiposity index (VAI) with MS in both men and women with prediabetes and diabetes, these findings allow us to conclude that VAI is a simple but effective indicator for estimating the presence of MS among adults.
The Biochemical Biomarkers Determination in Alzheimer Dementia
Authors: Birlutiu Victoria , Stef Laura , Cernusca Mitariu Sebastian Ioan , Filip Corina Roman , Duica Lavinia , Antonescu Elisabeta , Pirlog Mihail , Purnichi Traian , Silisteanu Sinziana Calina , Manea Marinela Minodora
Published: February 2020

Alzheimer�s disease (AD) is a complex neuropsychiatric condition characterized by progressive cognitive symptoms.The social and psychological costs associated with the care of AD patients are very high; therefore, significant funds for research in this field are being invested worldwide. The accuracy of medical methods for establishing the diagnosis of AD with specific neuropathology is very important. Biomarkers can detect AD in their pre-clinical stage, monitor the disease progression, and detectmore objectively the treatment response. We performed a retrospective study of 100 patients admitted to the Gheorghe Preda Psychiatric Hospital of Sibiu with the diagnosis of Mild Cognitive Impairment and Alzheimer�s Dementia. The diagnosis was established according to the Diagnostic and Statistical Manual Disorders-4th edition criteria and the severity of the condition was determined by the Mini Mental State Examination. Our retrospective study revealed that in a certain period of time, most hospitalized patients with AD had the most days of hospitalization; they were patients in severe stage, due to the needs of multidisciplinary care and the multiple possibilities offered by medical staff. At present, AD research, in addition to finding therapeutic remedies in the clinical stages of AD, also aims at primary and secondary prevention strategies, including the detection of biomarkers in the pre-clinical stage of AD.
Effects of Agricultural Activities on the Environment
Authors: Rahoveanu Adrian Turek
Published: February 2020

With the development of intensive farming through the use of fertilizers, pesticides, it has become increasingly polluting. This is why they are pushing for the return of sustainable agriculture. Sustainable agriculture has as major objectives the optimization of productivity, while preserving the basic natural resources. This means that in agricultural production systems, it is imperative to maintain a balance between inputs and outputs, between investments and benefits, while ensuring the protection of the environment and the promotion of a sustainable economy as a whole. Due to intensive farming, using pesticides, chemical fertilizers, or residues from zootechnical activities, soil is the main affected. Most soils are losing their nutrients and organic matter in a higher proportion than the process of their regeneration, which leads to their depletion, resulting in irreversible degradation. Soil pollution means any action that causes the disruption of normal soil functioning as a support and living environment within natural ecosystems.
Flash-Free Orthodontic Adhesive System Compared with the Conventional Direct Bonding Method
Authors: Szuhanek Camelia , Golban Denisa Maria , Negru Radu , Negrutiu Meda Lavinia , Marsavina Liviu , Duma Virgil Florin , Sinescu Cosmin , Porojan Liliana
Published: February 2020

The latest technology in the field of orthodontic materials is represented by the Flash-Free Orthodontic Adhesive System. In the present study this novel technique is compared with the conventional direct bonding method. Ten extracted human premolars were separated into two groups: in the Group 1, APC Flash-Free Adhesive Coated Appliance System (3M Unitek, Monrovia, CA, USA) was bonded, while in the control Group 2, Clarity Advanced braces (3M Unitek, Monrovia, CA, USA) were bonded using XT Adhesive Paste (3M Unitek, Monrovia, CA, USA) applied by the clinician on the bracket base. Bonding times were recorded for each sample. Shear bond strength (SBS) was recorded using Zwick Zoel Z005. After debonding, the adhesive remnant index (ARI) was established for both groups. Group 1 showed a mean bonding time of 21 s, while Group 2 needed about 45 s for each bracket bonding. Both groups had clinically accepted SBS values, but the difference between them was significant (10.97 MPa versus 8.23 MPa). ARI scores were equal to 1 for most samples. In conclusion, reducing the time for bracket placing, APC Flash-Free Coated Appliance System showed a brackets bonding time reduced to half compared to the conventional technique. This aspect, combined with significantly higher SBS values, makes this novel system better than the classical one. For both groups, more than half of the adhesive remained on the bracket base, which facilitates cleaning after debonding.
Correlations Between Cytomegalovirus Infection and Cutaneous-Mucosal Manifestations of Immune Thrombocytopenic Purpura
Authors: Badulescu Oana Viola , Badescu Magda , Ciocoiu Manuela , Mocanu Madalina
Published: February 2020

Immune thrombocytopenic purpura is a pathological condition in which the decrease in the number of circulating platelets outlines a polymorphic picture. It takes the form of a haemorrhagic syndrome at the facial and mucosal level, manifesting usually through epistaxis, gingivorrhagia, bruising, petechial purpura. Mechanisms of disease onset and symptomatology are not fully known, yet many studies concluded that infectious factors and immunological disorders are involved in the etiopathogenesis of immune thrombocytopenic purpura. Infectious diseases with a possible etiological role in triggering a secondary thrombocytopenic syndrome are predominantly viral: hepatitis virus (B, C) infection, HIV infection, infectious mononucleosis or Cytomegalovirus infection. This paper aims to highlight the involvement of Cytomegalovirus infection in the occurrence of antithrombotic antibodies and haemorrhagic manifestations of immune thrombocytopenic purpura. Determination of the anti-Cytomegalovirus viral serology was performed using the immunochemical method of electrochemiluminescence detection (ECLIA).
Ethical Aspects in Pediatric Radiology
Authors: Tigmeanu Codruta Victoria , Porumb Anca , Podariu Alexandra Sabina , Adomnicai Mihaela Florica , Krems Cristian Dan , Ciobanu Virgil , Dejica Simina Camelia , Podariu Angela Codruta
Published: February 2020

Pediatric dentistry has become, in recent decades, a freestanding discipline, from the desire to improve dental assistance offered to children. It is a highly complex medical specialty, involving the triad of minor patient, doctor and the legal guardian of the patient. In conformity with European Community law, Law no. 95/2006 of Romania says it will get a written consent from the patient or his legal guardian; the methods of prevention, diagnosis and treatment of potential risk to the patient. Minor patient will be informed during the process of making decisions according to his understanding skills, (Law 46/2003), the final decision for acceptance the treatment belongs to the parents (consent of one of them is sufficient) or the legal guardian and the consent must be given in a written form (Law 95/2006; Bucur S.&al 2014). But conception as well as the doses used in pediatric dentistry are different from those used for adults. This paper aims to aware of dentists on ethical issues related to the indication of making child patient dental radiographs, in conformity with the recommendations and radiological current European rules (Guidelineson the use of dental radiographs, 2003).
Changes of Thyroid Hormonal Status in Organophosphate Exposure A systematic literature review
Authors: Tomescu Dana , Cobilinschi Cristian , Tincu Radu Ciprian , Totan Alexandra , Neagu Tiberiu Paul , Diaconu Camelia Cristina , Tiglis Mirela , Bratu Ovidiu Gabriel , Macovei Radu Alexandru
Published: February 2020

Organophosphates (OP) are widely used in both agriculture and household settings as pesticides. Human exposure is mainly due to residues in food or living environment and the main mechanism of OP toxicity are the acetylcholinesterase (AChE) inhibition. Acute poisoning is associated with a high rate of mortality due to parasympathetic overstimulation. In long-term exposure, OP are linked to systemic damage occurrence like nervous, hepatic or renal dysfunction. These compounds are considered as potential endocrine disrupters, causing significant hormonal imbalance targeting the adrenals or thyroid glands. The aim of this article is to review current data in the literature regarding effects of both acute and chronic OP exposure on thyroid hormonal status.
Peripheral Neurotoxicity Induced by Taxanes, Cisplatin, Oxaliplatin, Fluoropyrimidines and Vinorelbine. A clinical perspective
Authors: Nitipir Cornelia , Baetu Alexandru , Voinea Andreea , Pietrosanu Catalina , Iaciu Cristian , Voichitescu Madalina , Hainarosie Razvan , Orlov Cristina , Negoita Silvius Ioan , Dutu Madalina Alina , Panea Cristina , Balalau Cristian
Published: February 2020

Chemotherapy-induced peripheral neuropathy (CIPN) is the type of toxicity that affects treatment decisions often. Oncology specialists usually grade it using Common Terminology Criteria for Adverse Effects version (CTCAE), with some limitations. Dyck scale is a more objective method that is usually used for diabetic neuropathy grading.The present study included retrospectively registered patients (n=80) treated with platinum salts, taxanes, fluoropyrimidines or vinorelbine that subsequently developed CIPN. In some, the decision to lower the chemotherapy dose or withhold the treatment altogether was taken. CIPN was graded using both CTCAE 4.0 and Dyck scale for each patient. The aim of the study was to determine how the grades of each scale influenced the decision on the oncological treatment and whether objective, measurable changes are directly proportional to the impact CIPN has on the patients life. The present study reports high sensibility for both CTCAE and Dyck scale in deciding to modify the dose or interrupt chemotherapy. CTCAE should have more importance for the clinician in the early stages of CIPN. If CIPN presents as advanced, a less subjective alternative like the Dyck scale is a more suitable alternative. Dyck scale should be the most important argument in the decision regarding oncological treatment if the patients� scores more than 2a on this grading system.The decision to lower the dosage or stop oncological treatment due to CIPN is a complex one and both grading systems are useful. However, when dealing with a more severe case of CIPN, the more objective Dyck scale should be the more important argument.
Correlation of Glycemic and Lipid Control Parameters with Cognitive Dysfunction Scores, in Type 2 Diabetic Persons Results from a cross- sectional study
Authors: Botnariu Gina , Popa Alina , Mitrea Geta , Manole Marius , Pacurar Mariana , Anghele Mariana , Curis Cecilia , Teodorescu Elina
Published: February 2020

Diabetes-related cognitive dysfunction is considered a long-term complication of diabetes. In this cross-sectional study was studied the relationship between cognitive dysfunction (assessed by using two standardized questionnaires), lipid profile parameters and fatty free acids intake, in outpatients, hospitalized for their periodical control. The Mini-Mental State Exam (MMSE) and The Montreal Cognitive Assessment (MoCA) score were related to the body mass index (BMI), high density cholesterol (HDLc), glycated hemoglobin (Hb A1c) and intake of choline and eicosapentaenoic acid (all Ps [ .05, excepting the relationship between MMSE and HDLc). The implications of FFA intake in dementia development, in type 2 diabetics, is important for disease management and prevention.
Consequences of Dental Occlusion Enhancement by Means of Metal Crowns on the Animal Model
Authors: Ispas Ana , Craciun Antarinia , Lascu Liana , Barbinta Patrascu Marcela Elisabeta , Constantiniuc Mariana
Published: February 2020

The purpose of this study was to determine whether there is a correlation between induced occlusal trauma and the occurrence of oxidative stress in the hippocampus. Twenty Wistar rats were randomized into three experimental groups and one control group. Animals in the experimental group were cemented modified crowns on molars to induce occlusal trauma in 7, 14 and 30 days. To evaluate the oxidative stress, blood was drawn from the hippocampus at 7, 14 and 30 day intervals. Oxidative stress was evaluated using the following specific tests: determination of plasma malondialdehyde and serum glutathione values. The results of the study demonstrate that malocclusion experienced by raising the vertical dimension in rats resulted in significant reductions in antioxidants and increase level of free radicals.
The Imidazoline Receptor Antagonists Idazoxan and Efaroxan Improve the Spatial and Reference Memory in Rats
Authors: Rusu-Zota Gabriela , Luca Andrei , Stanciu Gabriela Dumitrita , Sorodoc Victorita , Leon-Constantin Maria Magdalena , Stoica Bogdan , Gales Cristina , Alexa-Stratulat Teodora
Published: February 2020

Experimental studies and clinical trials revealed the complex interconnections between imidazoline system and various other mediators such as epinephrine, norepinephrine; thus, explain their involvement in the pathophysiological mechanisms of different motor, behavioral and cognitive disturbances. In this study, we tested the influence induced by idazoxan and efaroxan on the cognitive performances in rats. Groups of 6 adult male Wistar rats were treated intraperitoneally according to the following protocol: group I (Control): distilled water 0.3 ml/100g; group II (IDZ): 3 mg/kg idazoxan and group III (EFR): 1 mg/kg efaroxan. The effects of the imidazoline receptor antagonists on the rats cognitive functions were assessed using the radial-arm maze, in order to count the time spent into the arms, the number of baited arms visited, but previously explored (working memory errors); the time taken to consume all baits and the number of entering in non-baited arms (reference memory errors). The data were expressed as mean +/- standard deviation, and statistically analyzed using SPSS version 17.0 Software for Windows, followed by ANOVA one-way method. The administration of IDZ, as well as of EFR was accompanied by a substantial diminution in the number of working memory errors, and the period of time to consume all baits, statistically significant (p[0.01) compared to control group. The use of these two imidazoline receptors antagonists resulted in a considerable decrease in the reference memory errors number, statistically significant (p[0.01) compared to the group treated with distilled water. The influence of IDZ on the evaluated parameters was more accentuated than the effects induced by EFR in all sessions of testing, in this behavioral experimental model. Our findings indicate that treatment with both imidazoline receptor antagonists, idazoxan and efaroxan was associated by a facilitation of the short-term memory retention, an enhancement of discriminative spatial learning, and an improvement of long-term memory performance in radial arm maze in rats.
Electro-chemical Corrosion of a Cast Iron Protected with a Al2O3 Ceramic Layer
Authors: Bejinariu Costica , Munteanu Corneliu , Florea Costel Dorel , Istrate Bogdan , Cimpoesu Nicanor , Alexandru Adrian , Sandu Andrei Victor
Published: February 2020

Thin layers of Al2O3 were used to protect a standard FC250 cast iron at electro-corrosion in acid rain electrolyte solution. In comparison with a cast-iron material we present the results obtained on the metallic covered sample using linear and cyclic potentiometry. The material surface was investigated using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) techniques. The results present a generalized corrosion with a higher resistance for covered samples (more than 30 times) in comparison with the simple cast iron. The main causes of the corrosion of the covered samples are based on the thin ceramic layer imperfections like pores or micro-cracks that facilitate the contact of the electrolyte solution with the metallic substrate.
Evaluation of the Environmental Impact by FTIR Gas Analysis of Organic Solvents Used in the Pharmaceutical Industry
Authors: Voinea Sanda , Axenie Theodor , Serban Alexandra , Nichita Cornelia
Published: February 2020

This paper presents the impact on the atmospheric environment of organic solvents used in pharmaceutical industry, investigated by FTIR gas analysis. The experimental data emphasized that this technique represents a fast and efficient method of analysis for gaseous emissions from studied solvents (ethanol, methanol, acetic acid). The study of the spectra samples indicates a good capability of the method to detect gases in indoor air from different concentrations and volumes of solvents in mixed solutions up to units of ppm and hundreds of micro liters. The results emphasized a good correlation between the concentrations of the solvents in the gaseous phase from the environment and the concentration of the solvent from the analyzed solutions. Moreover, the study shows the persistence in time of the air pollution in the technological areas of pharmaceutical and chemical industries.
Circulating 25-hydroxycholecalciferol in Relationship to Central Dual-Energy X-Ray Absorptiometry Assesses. A clinical study
Authors: Albulescu Dana Maria , Carsote Mara , Ghemigian Adina , Popescu Mihaela , Predescu Anca Mihaela , Tuculina Mihaela Jana , Bugala Adelina Smaranda , Bataiosu Marilena , Marinescu Roxana Iulia , Dascalu Ionela Teodora , Stan Mihaela , Cumpata Cristian Niky , Bechir Edwin Sever
Published: February 2020

The aim of the research was to realize a clinical study on menopausal patients, focused on 25-hydroxyvitamin D (25OHD) assays versus Dual-Energy X-Ray Absorptiometry (DXA) categories. This transversal, observational, real-life study was effectuated on Caucasian Romanian females. A total of 60 subjects were grouped according to lumbar T-score: normal T-score (N=28), osteopenia (N=22), and osteoporosis (N=10). The lowest average value of 25OHD is found in patients with osteoporosis, which is statistically significant lower than in patients with osteopenia. The average values of PTH were within normal levels for each group. 25OHD did not correlate with PTH or lumbar BMD. Overall the mean values of 25OHD are in deficient ranges regardless osteoporosis, osteopenia or normal DXA.
The Value of Adenosine Deaminase Enzime Level in the Positive Diagnosis of Tuberculous Pleural Effusion
Authors: Cojocaru Viorica , Dantes Elena , Novac Mariana Gabriela , Ionescu Alexandra Maria , Ianosi Edith Simona , Rusu Elena , Nemes Roxana Maria
Published: February 2020

The etiologic diagnosis of pleural effusion is often difficult, requiring invasive investigations to determine it. In Romania, tuberculosis is a frequent cause of pleural effusion, with the diagnosis of certainty being based on the bacteriological or histopathological examination. Adenosine deaminase (ADA) is an enzyme found in T lymphocytes, stimulated by Mycobacterium tuberculosis, which is why it is considered to be an essential marker of etiologic diagnosis in countries where the TB endemic is elevated. A case-control study was conducted in the Clinical Pneumophthisiology Hospital of Constanta, Romania, in patients diagnosed with tuberculous pleural effusion. The primary endpoint was to establish the cut-off value for ADA in supporting the positive diagnosis of TB pleural effusion, and the secondary objective was to identify the differences between TB pleural effusion and other etiologic types of pleural effusion. A cut-off of 55 UI has a good specificity (80%) and good sensitivity (85%). The study confirms other features of tuberculous pleural effusion as younger age, lower levels of white blood cells and neutrophils, increased number of lymphocytes in pleural fluid, low protein serum level, increased values of pleural lactic dehydrogenase (LDH) and pleural ADA.
Microscopic and Molecular Detection of Nosema ceranae in Honeybee Apis mellifera L. from Romania Status on pathogen worldwide distribution
Authors: Mederle Narcisa , Lobo Maria Luisa , Morariu Sorin , Morariu Florica , Darabus Gheorghe , Mederle Ovidiu , Matos Olga
Published: February 2020

Until now, in Romania, a country in southeastern Europe located on the Balkans Peninsula, information regarding the status on A. mellifera honey bee infection by Nosema spp. has not been published. The aims of the present study were to survey the occurrence and identification of Nosema spp. in A. mellifera honeybee colonies from 37 apiaries located in Arad, Caras-Severin and Timis Counties, Romania. Also, based on published literature an update on the distribution of N. ceranae infection among A. mellifera colonies worldwide was performed. Overall, a frequency of 55.1% (389/690) of Nosema infection was observed in the analyzed regions (ranging from 52% to 66%), by light microscopy. By PCR and DNA sequencing, N. ceranae was the only microsporidia identified. Nosema ceranae is clearly a novel, emergent pathogen of A.mellifera with potentially very serious effects on the individual and honeybee�s colonies in Romania. Data obtained provide new and important information on N. ceranae geographic prevalence and distribution, and on its impact at colony level and/or its role in colony losses. The present study intends to contribute to highlight the importance of implementing prevention, treatment and control measures of honeybee nosemosis, in Romania.
Employment of Simulants for Testing Constructive Materials Designed for Body Surface Isolative Protection in Relation to Chemical Warfare Agents
Authors: Otrisal Pavel , Florus Stanislav , Barsan Ghita , Mosteanu Danut
Published: February 2020

Employment of simulants, thus spare testing compounds always takes the bigger value in the area of testing garments designated for body surface protection against the effects of chemical warfare agents. The aim of simulants usage is mainly to remove problems related to manipulation with high toxic compounds and to enable testing to such working places that have not got the permission for the treatment with chemical warfare agents and other highly toxic compounds. The paper summarizes some achieved results of measurements of chemical resistance which have been performed based on simulants. These results are put into mutual connection with the sulfur mustard which is recently used as a standard testing chemical compound.