bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding Antibiotic Influence on Medical Test Outcomes: A Systematic Review
Authors: Alanazi Abdulrahman Alani , Alrewaili Fahad Saleem , Alshammari Yosaf Mohamad , Alenazi Khaled Hendi , Alanazi Haitham Muzil , Alanazi Faisal Shutayt
Published: November 2024

Objective: This systematic review examines the effects of antibiotic administration on the accuracy of medical test outcomes, aiming to provide healthcare professionals with insights into the diagnostic challenges posed by antibiotic interference. Methods: A comprehensive literature search was conducted across databases including PubMed, Scopus, and Web of Science, covering studies published between 2016 and 2024. Studies were selected based on their focus on antibiotic interactions with diagnostic tests in clinical settings, with strict inclusion and exclusion criteria applied. Data were extracted from relevant studies, focusing on specific medical tests affected, types of antibiotics involved, and outcomes observed. Quality assessment was conducted using PRISMA guidelines to ensure the reliability of included studies. Results: The review identified multiple instances where antibiotics influenced the accuracy of key diagnostic tests. For example, antibiotics commonly impacted blood culture results, leading to false negatives in detecting infections. Urinalysis and inflammatory marker tests were also affected, often resulting in reduced sensitivity and specificity. Liver function and renal function tests showed variability in results due to certain antibiotics, potentially complicating patient assessment. Mechanistic insights suggest that antibiotic effects on bacterial growth, immune modulation, and metabolic interactions are primary contributors to altered diagnostic results. Conclusion: Antibiotic administration can significantly interfere with various diagnostic tests, posing risks to accurate diagnosis and timely intervention. These findings highlight the importance of obtaining a thorough medication history and considering potential test interference in clinical decision-making. Further research is recommended to develop guidelines for minimizing diagnostic inaccuracies due to antibiotic influence.
Forensic Pathology and Unnatural Death Investigations: A Systematic Review of Case Studies and Procedures
Authors: Almakrami Hussain Abdullah Hassan , alsogoor Hamad mahdi Saleh , Alsulayyim Teflah Saeed Ali , Alhokash Hadi Abdullah Hadi , Jali Abdullah saleh ali , Lasloum Saleh obeid hadi , Al Sallum Dhafer Obaid Hadi , AlHarmes Hadi Salem Nasser , HUMAYYIM SAEED AWADH ALI BANI , ALTALAILI TALAL ALLAS MAHDI
Published: November 2024

Forensic pathology plays a crucial role in investigating unnatural deaths, providing insights that influence legal and judicial outcomes. This systematic review examines case studies and procedures in forensic pathology to identify common methodologies, challenges, and trends in unnatural death investigations. By analyzing a selection of case studies across various regions and types of deaths, including homicide, suicide, and accidental deaths, this review highlights the standard forensic techniques employed—such as autopsy, toxicology, DNA analysis, and imaging technologies—and discusses their impact on case resolution. Findings indicate significant advancements in technology and methodology, yet also reveal challenges such as jurisdictional variations, resource limitations, and inconsistencies in procedure standardization. This review underscores the need for uniform forensic protocols to improve investigative outcomes and legal accuracy. Recommendations include adopting standardized practices, improving resource allocation, and encouraging further research into underexplored areas of forensic pathology. This work aims to provide forensic professionals, policymakers, and researchers with insights that contribute to the refinement of death investigation procedures and support the justice system.
The Collaborative Pulse of Healthcare: a critical analysis of Nursing’s Role in a Holistic Approach to Patient Care Across Medical Specialties
Authors: Alsari Rehab saleh Ali , Al Dighrir Khalid  mohamad hassan , Alyami Amal Salem Mubarak , Alnajrani Felwah Mahdi Rashid , Al sharif Mohammed ahmad hussain , Alshtewi Ali Khalid Hussain , Alhareth Hamis Abdullah Saleh , Alsogour Fatmah Mahdi Rashed , Alnajrani Sabrin Mohammed Mahdi , Almasabi Fares Mohammed , Al yami Hannoda Essa saeed
Published: November 2024

This critical analysis explores nursing's pivotal role in fostering a holistic approach to patient care within multidisciplinary healthcare teams. As healthcare becomes increasingly complex, the integration of collaborative practices across specialties is essential for delivering comprehensive and patient-centered care. Nurses, often serving as the main touchpoint for patients, play a crucial role in coordinating care, advocating for patient needs, and bridging communication among healthcare professionals. This study examines the specific contributions of nurses, identifies challenges in inter-professional collaboration, and highlights enablers that support effective teamwork. Findings suggest that nursing collaboration positively impacts patient outcomes, satisfaction, and care continuity, though challenges such as communication barriers and hierarchical structures remain. By enhancing support for collaborative nursing roles, healthcare institutions can achieve improved quality of care and greater efficiency. Recommendations include promoting interdisciplinary training, clarifying team roles, and implementing policy reforms to empower the nursing workforce in holistic patient care.
The Impact of Effective Coaching on Sales Performance Mediated by the Role of Soft Skills in the Tourism Industry
Authors: Mhmood Mohmmed Raoof , Sani Mohsen Alizadeh , Safari Mohammad , Shirkhodaie Meysam , Azeez Reyath Thea
Published: November 2024

This research aimed to design a model for the role of effective coaching in achieving sales representatives' performance through soft skills for Iraqi tourism companies using quantitative and qualitative approaches. A questionnaire was designed to collect data to analyze the relationship between the research variables for (427) paragraphs that were randomly distributed to each tourism salesperson. To prove the model, five hypotheses were formulated where the effect and relationship were proven in all hypotheses using (SPSS, SMART PLS) programs. The results emphasize the importance of implementing strong coaching programs aimed at developing self-awareness, personal responsibility and personal skills among employees. Moreover, the study highlights the need for tourism service providers to comprehensively assess and develop personal skills alongside technical competencies during recruitment and performance management processes. It recommends providing value for the potential benefits of implementing coaching programs to support professional development and enhance the performance of front-line sales personnel. The results of this research can help in developing coaching strategies and coaching programs specifically designed to improve salesperson performance, and ultimately improve customer experience in the tourism services sector.
Community Value Co-Creation as a Catalyst for Village Tourism Sustainability: A New Paradigm
Authors: Noor TB.Dicky Faldy Syahid , Hamsal Mohammad , Abdinagoro Sri Bramantoro , Raharjana Destha Titi
Published: November 2024

The purpose of this study is to propose a new conceptual model for tourism marketing management science, focusing on the perspective of the head of the tourist village manager to achieve village tourism sustainability. This study employs a quantitative approach and includes data from 140 respondents. The data pertains to the green environment mindset, local wisdom, community co-creation, and sustainable tourist villages. A quantitative research method was utilized in this study, with the head of the tourist village manager representing Indonesia. Data collected from 140 tourist village managers were analyzed using Smart PLS-4. This study's main findings emerged from the mediation hypothesis test results. Increasing community value co-creation, supported by the green environment mindset and local wisdom, contributed to sustainable tourist villages. This study adopts the perspective of service-dominant logic.
Applying Cognitive Neuroscience to Juvenile Justice: The Role of Brain Development in Decision-Making
Authors: Şentürk Lara Gülten
Published: November 2024

The intersection of cognitive neuroscience and juvenile justice offers profound insights into understanding the role of brain development in decision-making among adolescents. This research explores the implications of neurodevelopmental processes, particularly in the prefrontal cortex and limbic system, which govern impulse control, risk assessment, and emotional regulation. Adolescents are at a stage of heightened neuroplasticity, which significantly influences their cognitive and emotional responses. This study examines how these developmental factors impact their decision-making and susceptibility to external influences, such as peer pressure. By integrating neuroscientific findings with legal frameworks, the research highlights the importance of adopting rehabilitative over punitive approaches in juvenile justice systems. The findings underscore the need for tailored interventions and policies that account for the neurobiological underpinnings of adolescent behavior, fostering a balance between accountability and the opportunity for growth and rehabilitation.
Neural Pathways of Social Cognition: From Systems Neuroscience to Psychosocial Applications
Authors: Şentürk Lara Gülten
Published: November 2024

The neural pathways underlying social cognition form the basis of human interaction, encompassing processes such as empathy, theory of mind, and social decision-making. This research explores the intersection of systems neuroscience and psychosocial applications, unraveling the neural circuits that enable individuals to perceive, interpret, and respond to social stimuli. Key brain regions such as the medial prefrontal cortex, temporoparietal junction, and amygdala play pivotal roles in these processes, facilitating complex functions like perspective-taking and emotional resonance. By integrating insights from neuroimaging, behavioral studies, and computational modeling, this study aims to map the mechanisms that govern social cognition and their disruptions in conditions such as autism, schizophrenia, and social anxiety. The research also emphasizes the translation of these findings into psychosocial interventions, including therapeutic strategies and social skills training programs. Understanding the neural underpinnings of social cognition has far-reaching implications for enhancing interpersonal relationships, fostering inclusivity, and addressing the challenges posed by neuropsychiatric disorders.
CRYPTOCURRENCY ADOPTION IN INTERNATIONAL MARKETS: CHALLENGES AND OPPORTUNITIES
Authors:   GAIL Global (USA) Inc., Houston, Texas-USA., khichi Mahendra K.
Published: November 2024

Cryptocurrency is next in the list of gigantic financial innovations in modern times, changing the way any person, institution, and the government interacts through the global economy. Starting with Bitcoin back in 2009, it refers to decentralized digital currency based on the blockchain technology that can help someone carry out transparent, peer-to-peer, and safe transactions without using banks. There are numerous reasons that have fueled interest in cryptocurrencies, including financial independence, high returns on investment, and increased privacy in transactions. As cryptocurrencies take the world by storm in most international markets, they present major challenges and unique opportunities in equal measure. The acceptance of cryptocurrencies varies widely from country to country, depending on the regulatory environment, technology infrastructure, and cultural orientation toward digital finance. Areas with supportive regulations and the most advanced technological ecosystems promote rapid adoption, while restrictions in policies and limited technology access have hindered adoption in other areas. Apart from that, the inherent volatility of cryptocurrencies gives rise to several concerns with regard to using them as reliable mediums of exchange or stores of value, which may discourage potential users and investors. Security, fraud, and how a cryptocurrency works raise issues with trust, thereby making acceptance complicated. Despite these challenges, cryptocurrencies hold the potential for revolutionizing financial systems through financial inclusion in underbanked regions and facilitating faster, cheaper cross-border transactions. This paper aims to explore what factors drive the adoption or do not of the cryptocurrency by international markets and their related business and consumer implications. Through multiple case studies and insights obtained from various regions, the work attempts to deliver a profound understanding of the challenges posed by cryptocurrency adoption and at the same time the possible opportunities, in order ultimately to show the transformative value that cryptocurrency has in shaping the rapidly changing global economy.
HOME CARE POST FEMUR FRACTURE SURGERY ON MR. A IN THE WATUBELAH AREA, CIREBON REGENCY IN 2024
Authors: Permatasari Leya Indah , Aldi Ramadan  , Dian Amelia  , Hoirunnisa Hoirunnisa , Nanda Meilizha  , Nurliana Nurliana , Seli Juliyanti  , Uun Kunaena
Published: November 2024

Home Care is a health service carried out at home and aims to improve, maintain, and increase the independence of patients and families. The home care activities at Mr. A aim to be a form of community service with the hope that the family can be independent in caring for Mr. A. The implementation of community service in the form of home care services uses a family nursing care approach, starting from conducting assessments, determining diagnoses, and providing interventions, documentation, and evaluations. The implementation of home care services is carried out for three days by providing education and wound care. After the wound was treated, Mr. A's wound no longer had fluid coming out of the wound, and when given education, Mr. A and his family understood what was conveyed.
DE LA MONUC A LA MONUSCO : PROBLEMATIQUE DE MAINTIEN DE LA PAIX ET DE LA PERSISTANCE DES CONFLITS ARMES EN RDC
Authors:   Assistante de Deuxième mandat à l’Université Pédagogique Nationale (UPN)/Kinshasa-RDC et Doctorante en Relations Internationales à l’Institut des Sciences Sociales-Université de Selçuk (Turquie), BUKUMBA Tabitha TABALA
Published: November 2024

Le présent article aborde la question des missions de maintien de la paix des Nations Unies en République Démocratique du Congo. Les analyses partent de la Mission des Nations Unies au Congo (MONUC) à sa mutation en Mission de l’Organisation des Nations Unies pour la Stabilisation du Congo (MONUSCO) en l’an 2009 et l’épineuse question de la persistance des conflits armés dans ce pays. Il en ressort que le bilan de maintien de la paix de la mission onusienne (de MONUC à la MONUSCO) est largement négatif. Ainsi, il est préconisé de privilégier le renforcement des capacités des Forces Armes de la RDC du point de vue logistique, motivationnel et stratégique et doter le pays des institutions crédibles et fortes au service du peuple et de la justice distributive. Mots-clés : Monuc-Monusco,Maintien de la paix, République Démocratique du Congo,Casque bleu.
LES MANGROVES : ECOSYSTEMES DE REGULATION ET DE PROTECTION CONTRE LE RECHAUFFEMENT CLIMATIQUE
Authors:   Assistant à l’Université Pédagogique Nationale (UPN)/Kinshasa-RDC et Secrétaire Général de l’Institut de Recherche en Géopolitique et d’Etudes Stratégique/Kinshasa-RDC, NGOMBA Felly LUKUNGA
Published: November 2024

Cette réflexion scientifique se situe dans le contexte actuel où le monde est marqué par le réchauffement climatique. Il se constate une menace permanente sur les écosystèmes et particulièrement les mangroves. Pourtant, il est prouvé, au cours de cette recherche, que les mangroves constituent des écosystèmes essentiels, du fait de leur potentiel en termes de séquestration du carbone et de protection de la biodiversité. Et de ce fait, il semble plus que nécessaire d’insérer cette espèce végétale dans les stratégies de lutte contre le réchauffement climatique et de gouvernance mondiale. Mots-clés : mangrove, écosystème, réchauffement climatique.
FIN DE LA GUERRE FROIDE ET DELUGE MINIER EN RÉPUBLIQUE DEMOCRATIQUE DU CONGO
Authors:   Chef de Travaux à l’Université Pédagogique Nationale et Directeur à l’Institut de Recherche en Géopolitique et d’Etudes Stratégiques (IRGES)/Kinshasa-RDC, LOSSIYO Patrick LOSSONGO
Published: November 2024

Cet article démontre que la spoliation des richesses minières dont la République Démocratique du Congo est victime, est en grande partie consécutive à la fin de la Guerre Froide par la perte de sa place géostratégique d’antan et par la jalousie de ses quelques pays voisins, en complicité avec certaines puissances mondiales désirant s’enrichir frauduleusement et illicitement avec ses richesses naturelles. Mots-clés : Guerre Froide, secteur minier, RDC.
La excisión en la Edad del Bronce y la primera Edad del Hierro
Authors: Abarquero Moras Francisco Javier
Published: November 2024

La técnica de la excisión se ha desarrollado desde la Prehistoria y manifestado en varias culturas europeas. El estudio, basado en los materiales hallados en la península Ibérica, abarca desde el Bronce Final hasta la primera Edad del Hierro y se centra en el análisis de las diferencias técnicas y estilísticas, así como en la evolución de las distintas variantes y en las manifestaciones culturales y sociales que forman parte de su contexto.
La cerámica con decoración excisa a bisel en el entorno cultural de los vacceos
Authors: Blanco García Juan Francisco
Published: November 2024

En los territorios vecinos al vacceo (habitados por turmogos, celtíberos, vetones y carpetanos) también está presente la técnica decorativa de la excisión, aunque de forma muy escasa y con variedades de estilo más limitadas, por lo que no se descarta que incluso se trate de importaciones con origen vacceo. El artículo trata de establecer las diferencias y coincidencias entre ambos grupos para inferir de esta forma posibles procesos de interacción social y cultural.
Ruecas, paisajes y sirenas de la colección de arte pastoril de José Ramón Cid en Ciudad Rodrigo (Salamanca)
Authors: Cid Cebrián Eugenio
Published: November 2024

Comienza este trabajo con una descripción geográfica, histórica y económica de la provincia de Salamanca, origen de esta colección de arte pastoril, así como una justificación de por qué se dan en esta provincia este tipo de representaciones. Se analiza la vida cotidiana del campesinado, de unos siglos atrás, resaltando el papel de la transmisión oral que, con la constancia del tiempo, cumplía la función comunicativa y regeneradora de los elementos culturales, ya fueran del orden laboral, de ocio o relativo a las creencias religiosas y mágicas. Analizamos distintas representaciones del arte pastoril realizadas en asta y madera, como ruecas, vasos y cuernos para el vino, colodras (grandes vasos de asta) para el ordeño y otras. Las imágenes decorativas analizadas son agrupadas como pertenecientes a ruecas, sirenas y paisajes, y van acompañadas de pájaras, peces, figuras mitológicas o de alusión religiosa y de decoración excisa geométrica.
Challenges in Translating Press Terminology in Arabic: An Analytical Study
Authors: Aliyev Ceyhun
Published: November 2024

This article explores the challenges of translating press terminology into Arabic, highlighting the importance of accurate translation for effective cross-cultural communication. Specific translation difficulties, including terms without direct equivalents, idiomatic expressions, and culturally sensitive phrases, are examined. Through a comparative analysis, the study identifies strategies such as standardization, adaptation, and paraphrasing to improve translation accuracy and readability. Recommendations for further research emphasize the need for standardized terminology and enhanced translator training to address these complexities and promote clarity in Arabic media.
DESAFIOS E COMPLICAÇÕES DA SÍFILIS CONGÊNITA: UMA REVISÃO LITERÁRIA
Authors: Moura Gustavo Fonseca de , Dantas Mayron Henrique Alves de Sá , Costa Hiago Camarço , Sousa Wesllen Silva , Bona Iolanda Felipe da Silva
Published: November 2024

A sífilis é uma patologia infecciosa majoritariamente transmitida de forma sexual, causada pela bactéria Treponema pallidum, que se não tratada pode evoluir para quadros sistêmicos, afetando a pele, coração, fígado e sistema nervoso central. Quando transmitida de forma vertical, por via transplacentária, o recém-nascido pode apresentar inúmeras complicações
TRATAMENTOS PARA ESQUIZOFRENIA ,DESAFIOS,E A BUSCA POR NOVAS ALTERNATIVAS VIÁVEIS PARA O MANEJO DA DOENÇA.
Authors: Oliveira Laura Virginia Sousa , Figueiredo João Victor Soares , Lima Victor Mayrink Braga Silva , Castro Bianca Mirian Garcia Martins , Kalbermatter Laura Carolina Andreo Gonçalves , Magalhães Aliandro Willy Duarte , Lucena Mávia Natália Batista , Seidel Eveline Alana
Published: November 2024

Objetivos:Realizar uma análise acerca do manejo no que concerne à Esquizofrenia,assim como os avanços tecnológicos que envolvem a mesma,bem como as perspectivas no que tange ao futuro do manejo da comorbidade com tratamentos alternativos.Metodologia:Trata-se de uma revisão integrativa de literatura, realizada a partir da busca por publicações científicas indexadas nas bases de dados: MEDLINE via PubMed, Cocrahne, Lilacs e SciELO. Os seguintes descritores foram utilizados:Esquizofrenia;Desenvolvimento tecnológico;Tratamento. Ao final das buscas, 10 publicações atenderam aos critérios de inclusão e  exclusão propostos,sendo elegíveis para o estudo.Resultados: Diante dos achados extraídos dos estudos selecionados, percebeu-se que os tratamentos formalmente disseminados para Esquizofrenia possuem limitações, sendo um desafio em relação a esse tratamento,a presença de múltiplos efeitos colaterais presentes nos antipsicóticos, assim, avanços tecnológicos como a utilização de terapias com a utilização de Inteligência artificial (IA) ,utilização de probióticos ,assim como o uso de eletroconvulsoterapia , podem proporcionar contribuições importantes para enfrentar as repercussões da doença, que tem sido considerada cada vez mais presente na sociedade.Conclusão: O seguinte estudo permitiu a reflexão acerca da necessidade de garantir tratamentos efetivos para o indivíduo com Esquizofrenia, promovendo melhora na qualidade de vida e maior sobrevida, utilizando para tal novos medicamentos e novas tecnologias. o apoio psicológico e social é essencial no manejo desses indivíduos em estado de vulnerabilidade.
JUIZ DAS GARANTIAS: INSTRUMENTO DE PROTEÇÃO DOS DIREITOS INDIVIDUAIS DO ACUSADO OU OBSTÁCULO À EFETIVIDADE DA JUSTIÇA CRIMINAL?
Authors: Pereira Filho Marco Antônio
Published: November 2024

O objetivo deste estudo é avaliar o impacto da possível implementação do juiz das garantias na preservação dos direitos fundamentais do acusado e na eficiência da justiça criminal brasileira. A pesquisa investiga a criação, os objetivos e os debates em torno do instituto, destacando a relevância da imparcialidade judicial no processo penal e os benefícios proporcionados pela figura do Juiz das Garantias, conforme a perspectiva garantista. O Juiz das Garantias, estabelecido pelo Pacote Anticrime (Lei nº 13.964/2019), é encarregado da fase pré-processual ou investigativa do processo penal e visa assegurar a neutralidade na condução das investigações criminais. Este estudo aborda as questões relacionadas à implementação desse instituto e sua correlação com a proteção dos direitos fundamentais dos réus. Através de uma revisão bibliográfica e análise documental, a pesquisa examina a decisão do Supremo Tribunal Federal que interrompeu a implantação do Juiz das Garantias e propõe possíveis alternativas para sua introdução no Brasil. Ademais, o estudo ressalta os impactos potenciais na eficácia da justiça criminal e na salvaguarda dos direitos fundamentais dos acusados. Como resultados, o estudo verificou que essa inovação pode ser percebida como uma oportunidade para aprimorar o trabalho dos magistrados, assegurando um processo penal mais justo e equilibrado, e fortalecendo a consolidação de um Estado Democrático de Direito no Brasil.
Association of Electrocardiographic Abnormalities With In-hospital Mortality in Adult Patients With COVID-19 Infection
Authors: Tarranza Jannah Lee , Ramirez Marcellus Francis , Yamamoto Milagros
Published: November 2024

OBJECTIVES: The study aimed to determine the association of electrocardiographic (ECG) abnormalities and in-hospital mortality of patients with coronavirus disease 2019 (COVID-19) infection admitted in a tertiary care hospital in the Philippines.

METHODS: We conducted a retrospective study of confirmed COVID-19–infected patients. Demographic and clinical characteristics and clinical outcomes were extracted from the medical records. Electrocardiographic analysis was derived from the 12-lead electrocardiogram recorded upon admission. The frequencies and distributions of various clinical characteristics were described, and the ECG abnormalities associated with in-hospital mortality were investigated.

RESULTS: A total of 163 patients were included in the study; most were female (52.7%) with a median age of 55 years. Sinus rhythm with any ECG abnormality (65%), nonspecific ST and T-wave changes (35%), and sinus tachycardia (22%) were the frequently reported ECG findings. The presence of any ECG abnormality was detected in 78.5% of patients, and it was significantly associated with in-hospital mortality (P = 0.038). The analysis revealed a statistically significant association between in-hospital mortality and having atrial fibrillation or flutter (P = 0.002),
supraventricular tachycardia (P = 0.011), ventricular tachycardia (P = 0.011), third-degree atrioventricular block (P = 0.011), T-wave inversion (P = 0.005), and right ventricular hypertrophy (P = 0.011).

CONCLUSION: The presence of any ECG abnormality in patients with COVID-19 infection was associated with in-hospital mortality. Electrocardiographic abnormalities that were associated with mortality were atrial fibrillation or flutter, supraventricular tachycardia, ventricular tachycardia, third-degree atrioventricular block, T-wave inversion, and right ventricular hypertrophy.

KEYWORDS: COVID-19, electrocardiography, mortality, Philippines
Hybrid Thoracic Endovascular Repair of a Large, Saccular Aortic Arch Aneurysm with Coil Embolization of the Left Subclavian Artery in a 31 Year Old Filipino Female with Takayasu Arteritis and Multiple Intracranial Aneurysms: A First in the Philippines
Authors: Marcellana Gwen R , Lacson Marie Antoinette , Samonte Precious Emary E , Alzate Ferdinand V , Martinez Marvin D , Posas Fabio Enrique B
Published: November 2024

BACKGROUND: Takayasu Arteritis (TA) is a rare, primary large-vessel vasculitis frequently leading to stenosis and less commonly, aneurysm formation. Saccular aneurysms of the aortic arch in patients with TA are fatal, have rarely been reported and represent a significant technical challenge due to the difficult anatomical location and need for protection of the cerebral circulation. Concomitant intracerebral aneurysms in patients with TA are extremely uncommon and have mostly been documented in very few case reports in literature.

CASE DISCUSSION: We present a case of a 31 year-old Filipino female with recurrent chest and neck pain radiating to the upper back. Computed tomographic (CT) angiography demonstrated a large saccular aortic arch aneurysm without branch stenosis. CTA of the cerebral circulation likewise demonstrated multiple, saccular, intra-cerebral aneurysms. She underwent hybrid thoracic arch repair with supra-aortic debranching via mini-sternotomy and proximal ligation of the left common carotid artery and staged endovascular aortic arch replacement with coil embolization of the ostial-to-proximal left subclavian artery segment. Post-operative aortogram showed optimal repair with thrombosed aneurysmal sac, optimal graft position, no endoleaks and preservation of cerebral circulation. Patient improved symptomatically post-procedure and remained symptom-free during follow-up after six months. Careful review of local literature suggests that this is the first Philippine TA case with a saccular aortic arch aneurysm successfully managed in this manner.

CONCLUSION: Saccular aortic arch aneurysms in patients with Takayasu are unusual and presence of concomitant multiple cerebral saccular aneurysms have rarely been reported in literature. This case highlighted that hybrid endovascular arch repair in patients with TA is feasible, minimally invasive and effective.

KEYWORDS: Takayasu arteritis, aortic arch aneurysm, cerebral aneurysm, hybrid endovascular arch repair, aortic de-branching
President's Message
Authors: Jimenez Rodney M
Published: November 2024

Congratulations on achieving inclusion in the Western Pacific Region Index Medicus (WPRIM) of the WHO Global Index Medicus! This remarkable milestone is a testament to the dedication of the Philippine Journal of Cardiology (PJC) team, led by Dr. Marcellus Francis "Mighty" Ramirez. Personally, I take great pride in seeing our previous research now easily accessible and recognized globally. This achievement realizes the vision our predecessors aspired to, and it inspires us to keep advancing. Let’s keep the fire burning and continue making a difference, one step at a time.
Cut a Tree, Cut a Man: Charcoal Production as a Bane to Green Economy in Nigeria
Authors: Olaniyan Adeola Seleem
Published: November 2024

Symbiotically speaking, cutting a tree is akin to cutting a man or any of its counterparts in the animal kingdom. Besides solar energy, heat energy's role in humans’ daily life calls for its taming, artificial ignition, and fuelling of same for its reuse as and when due. Hence, humans’ ability to ignite and fuel fire marked a significant achievement in human evolution. Meanwhile, wood was the most traditional source of fuel in human history, which is, mainly, of two forms: firewood and charcoal. Dried wood was the common source of fuel for domestic cooking and commercial use both in the rural and urban areas in the primitive era. Although, firewood has relatively little burden on nature, charcoal, which has more adverse effects on the environment, is now taking over. Sadly, the discovery of better alternative sources such as LPG and electricity could not bring about a remarkable shift in many developing nations, including Nigeria, despite their efficiency. Taking expository and critical analysis methodologies, this paper argues that wood-fuelling hinders the achievement of the green economy in Africa, and it persists for many reasons; poor state of electricity, unavailability and/or unaffordability of the LPG, poverty, poor environmental awareness, unsophisticated and poor enforcement of environmental laws and lack of compensation for the conservators among others. In addition to the ever-suggested solutions, this paper recommends a ‘carrot and cane' system. By this, the offenders should not only be accordingly penalised but also the conservers be compensated duly. It also recommends the use of briquettes as viable alternatives.
M-Poma: Innovative Technology for Boosting Exclusive Breastfeeding Practices
Authors: Ramli Nurlaili , Anita Anita , Magfirah Magfirah
Published: November 2024

Background: The Indonesian Health Survey data indicates that exclusive breastfeeding coverage is projected to reach 55.5% in 2023, with Aceh showing a lower rate of 49.9%. In Aceh Besar, the coverage was reported at 55.9% in 2022. Notably, women from low-income backgrounds are less likely to engage in breastfeeding practices by the second day postpartum compared to their higher-income counterparts. To address this disparity, the use of smartphone applications offering educational videos about breastfeeding and infant behavior has emerged as a preferred method, particularly among low-income mothers.
Objective: This study aims to develop a mobile application called “POMA” (M-POMA) to enhance exclusive breastfeeding practices among infants in the Kuta Baro District of Aceh Besar.
Methodology: A Research and Development (R&D) approach was employed to create the Android-based M-Poma application. The development process spanned two years: the first year focused on application design and functionality, while the second year involved training sessions for 25 midwives and 25 community health cadres. These training sessions were critical for testing the application and gathering user feedback.
Results: Based on the first year of research, the M Poma application was developed through a collaborative process, including FGDs and in-depth interviews, to ensure the application meets the needs of the community. Year 2 training was conducted for cadres and midwives to provide their valuable input on the application. The M-Poma application has been developed to support exclusive breastfeeding, which is essential for improving infant health. Feedback from Focus Group Discussions (FGD) highlighted the need for content on exclusive breastfeeding, user profiles, and case examples. Training sessions with midwives and community health cadres confirmed that the application is user-friendly, featuring an attractive interface and clear educational materials. Respondents emphasized the importance of a simple login process, engaging visuals, and easily accessible content. The majority of participants found the application’s features intuitive and appreciated the ease of data management within user profiles.
Conclusion: While the M-POMA application has made considerable strides, there are still areas that require revision. We highly value the feedback provided by users and remain dedicated to enhancing the application to ensure it is both appealing and efficient.
The Effectiveness of Temulawak (Curcuma Xanthorriza) Plus Honey in Increasing Children Under Five Years’ Body Weight
Authors: Nuryanti Erni , Saptaningrum Epi , Joni Siswanto  , Adi Isworo  , Sitepu Frans Yosep , Noviyanti Laila Auliya
Published: November 2024

Background: Malnutrition is still nutrition problem in Indonesia. One of the factors is the loss of appetite of children. In empirical side, Temulawak (Curcuma xanthorriza) is known having effect of increasing appetite. Honey is a natural ingredient that has been used for its energy and can stimulate appetite. This study aimed to determine the effectiveness of Temulawak plus honey on toddlers’ body weight gain in Blora District, Central Java, Indonesia.
Materials and methods: This was a quasi-experimental study design. The subjects were children aged 1-5 years old. Treatment group received 250 gr powdered Temulawak and 1 tablespoon of honey and mixed with 125 cc mineral water. While the control group just received 250 gr powdered Temulawak mixed with 125 cc mineral water. All the subjects drank two times in every day (morning and evening before eating) lasts for 30 days. Body weight was measured before and after the treatment. Independent t-test was employed to test the difference mean of body weight in treatment and control group.
Results: The study resulted that the average mean in the treatment group was 1.247 kg while in the control group was 0.393 kg. There was difference mean of body weight gain between treatment and control groups. The treatment group resulted the body weight gain statistically significant (p<0.001).
Conclusions: This study approved that Temulawak (Curcuma xanthorriza) plus honey effective in increasing children under five years old body weight. It is strongly recommended to give Temulawak plus honey for children who have loss of appetite to prevent them from malnourished status.
Comparison of Clinicopathological Features between Premenopausal and Postmenopausal Female Breast Cancer Patients in Kurdistan Region of Iraq: A Retrospective Single Institution Study of 671 Female Patients
Authors: Saeed Ariwan , Ameen Hazha Abdullah , Ali Jalil Salih
Published: November 2024

Introduction: Breast cancer is the most common cancer in women, and its incidence is increasing annually worldwide. It accounts for 24% of new cancer cases and 15% of cancer deaths in 2018, and according to the GLOBOCAN Cancer Tomorrow prediction tool, incident cases are expected to increase by more than 46% by 2040. Studies carried out thus far have shown that risk factors and histopathological features of breast malignancies may vary among different age groups. Menopausal status is an essential factor influencing clinicopathological characteristics of patients with breast cancer. Prognostic factors are used to estimate how aggressive the tumor may evolve and to decide on a treatment approach. In Iraq, breast cancer is most frequently seen in younger women in their fourth and fifth decades of life, who often show in advanced stages at the time of diagnosis, according to previous surveys.
Objectives: The main objective of this study was to assess the clinicopathologic features between premenopausal and postmenopausal breast cancers to provide valuable insights into what may influence the age at diagnosis of breast cancer in the Kurdistan region of Iraq.
Methods: This retrospective study included 671 non-metastatic breast cancer patients referred to  Zhianawa Cancer Center between January 2015 and December 2017. Disease stage was determined using the American Joint Committee on Cancer and Union for International Cancer Control (UICC) (“Tumour,” “Nodes,” “Metastases”) TNM systems. The patients were divided into premenopausal and postmenopausal groups. The chi-square test was used to evaluate the association between the variables.
Results: The mean age of the participants was 47.5 years. The most prevalent age group was 40-49, followed by the age group 50-59. Of the participants, 60.5% were premenopausal, and 39.4% were postmenopausal. Stage IIIA  was the most common stage at diagnosis. At the same time, the most minor stage at diagnosis was stage 0. The second most common stage was IIB. There was a strong association between menopausal status with grade (P value 0.001) and LVI (P value 0.01); however, there was a non-significant correlation between menopausal status and stage at diagnosis (P value 0.529).
Conclusion: Most patients included in this study had locally advanced disease stages. Menopausal status affected grade and LVI but not stage. Further professional efforts, endorsed by practical policy decisions, are recommended to down stage breast cancer through promoting evidence based protocol guidelines and adopting comprehensive well designed diagnostic, screening and cancer control strategies.
Intragastric Balloon Placement as an Effort for Weight Reduction in Morbid Obesity Cases
Authors: Giarena  , Widodo Budi
Published: November 2024

In The background: The term "morbid obesity" refers to cases of obesity with a body mass index (BMI) ≥ 35 kg/m² accompanied by health conditions related to obesity. Intragastric balloon placement is a non-surgical endoscopic bariatric therapy for obesity. We present a case of morbid obesity that underwent intragastric balloon placement.
Case report: A 36-year-old woman experienced continuous weight gain over the past 10 years. Various attempts to lose weight had been made, but none were successful. She reported worsening heartburn over the last 3 months, which did not improve with medication. The BMI was calculated at 35.6 kg/m². Gastroscopy revealed mucosal hyperemia in the distal one-third of the esophagus, concluding that the patient had esophagitis. An intragastric balloon was placed via endoscopy, and the patient followed a special diet after the procedure. One month after placement, a weight loss of 9 kg was observed, and her heartburn complaints had significantly improved.
Conclusion: We report a case of morbid obesity that improved following intragastric balloon placement. This non-surgical endoscopic bariatric procedure is the first of its kind performed in Surabaya.
Effectiveness of Schroth Therapy in Improving Self-Perception, Body Image, and Quality of Life in Patients with Adolescent Idiopathic Scoliosis: A Systematic Review
Authors: Sinaj Enkeleda , Stanaj Luljeta , Gul Muneeba , Selda (Veizaj) Sokoli  , Olsa Meta  , Silvio Selfo  , Denada Selfo Dr
Published: November 2024

Introduction: Adolescent idiopathic scoliosis is a structural spinal deformity that not only affects physical health but also has significant psychosocial consequences, such as body image disturbances, reduced self-perception, and diminished quality of life (QoL). Schroth therapy, a physiotherapeutic intervention designed to address scoliosis through three-dimensional exercises, has shown promise in managing these outcomes. This systematic review aims to evaluate the effectiveness of Schroth therapy in improving self-perception, body image, and QoL in adolescents with AIS.
Methods: A systematic review was conducted following PRISMA guidelines. Studies published between 2015 and 2024 were identified using PubMed, Embase, and Cochrane Library databases. Randomised controlled trials (RCTs) involving adolescents aged 10-18 years with AIS, receiving Schroth therapy as the primary intervention, were included. Outcomes measured were self-perception, body image, and QoL, assessed using tools like the SRS-22/23 and WRVAS. The risk of bias was evaluated using the Pedro scale.
Results: Six studies, with sample sizes ranging from 28 to 60 participants, were included in this review. The Schroth therapy group demonstrated significant improvements in self-perception, as measured by the Walter Reed Visual Assessment Scale (WRVAS), with a between-group difference of 6.5 points (95% CI: 3.2 to 9.9, p < 0.01, F = 169.5) reported by Buyukturan et al. (2024). Additionally, improvements in the self-image domain of the SRS-22 questionnaire were observed, with a mean change of 0.149 (95% CI: 0.001 to 0.297, p = 0.049) noted by Zhang et al. (2024). In terms of quality of life (QoL), one study by Kocaman et al. (2021) found a 15% increase in overall SRS-22 scores (p = 0.02), while the combined SE + ASSE group exhibited significant improvements in QoL compared to the SE-only group (p = 0.019) as shown by Khaledi et al. (2024). While other measures, such as Cobb angle and back muscle endurance, showed significant results, the focus of this review highlights the notable benefits of Schroth therapy on self-perception and QoL.
Conclusions: Schroth therapy appears effective in enhancing self-perception, body image, and quality of life in adolescents with AIS. While current evidence supports its psychosocial benefits, further long-term studies with larger sample sizes and more sensitive assessment tools are needed to validate these findings.
Bacteriophages and Bacterial Resistance: The Link
Authors: Talavera-González Juan Martín , Talavera-Rojas Martín , Reyes-Rodríguez Nydia Edith , Vega-Sánchez Vicente
Published: November 2024

Bacterial resistance is a public health problem that has caused the most deaths in the world; Various international organizations have launched an emergency call for attention to this problem. One of the main factors that contribute to its appearance is the inappropriate use of antibiotics, which generates the appearance of bacteria with specific genes that shield them from exposure to these drugs. In nature there are elements such as bacteriophages that have the ability to "steal" these genes from inside bacteria and transport them to other bacteria in different environments; In addition, due to their propagation, they are considered one of the links that contribute the most to the dissemination of genes, causing public and veterinary health problems as well as economic losses in different sectors such as agriculture and agriculture.
Reasons Pertaining to Substance Abuse among Undergraduates in Chennai
Authors: Babu Aadhya , Niren Savitha
Published: November 2024

BACKGROUND: Substance abuse and dependence among undergraduates in India are very concerning as they are next in line to contribute to the social and economic needs of the country. The alarming increase in substance use also contributes to various physical and mental illnesses. OBJECTIVES: This research aims to identify the root cause and initial indulgence in substance consumption to prevent the increase of usage and loss of human potential to enhance the quality of society in the upcoming years. METHODS: An observational study with a cross-sectional design was done among 174 participants. This questionnaire-based cross-sectional study was done among undergraduates aged between 19-22 in Medical, Dental, Engineering, and Arts and Science College students studying in Chennai. A Drug and Alcohol (DAP) questionnaire for screening of alcohol, tobacco, and cannabis along with a Semi-Structured Performa about socio-demographic factors was used to collect the data. Statistical analysis was carried out using SPSS version-21, Chi-Square Test descriptive for finding out the outcome variable. RESULT: About 62.7% tried alcohol/smoking for the first time because they were ‘curious’ followed by 29.4% stating that it was due to ‘emotional disturbances’, 23.5% due to ‘having free time’, 19.6% because they were ‘stressed’,17.6% due to ‘college’ as the three most chosen reasons. Among 45 participants who were consuming substances, 32.4% felt neglected at home. Of the remaining 133 who did not consume any substances when asked the reason for their non-consumption, 28.7% were ‘not interested', 15.7% said it was due to ‘self-control’ and 5.6% said ‘both’. CONCLUSION: Our study revealed that ‘curiosity’ was the reason for the initial consumption of the substance but the reason for the continuation of the habit is because of emotional disturbances, stress, or feeling neglected at home and by society. Prevention and treatment of substance abuse and dependence should consider these factors. This can help lay better intervention and relapse strategies for the upcoming generation.
A Comprehensive Review on the Anti-Obesity Potential of Limonia acidissima L., and its Bioactive Compounds: Mechanisms and Applications in Weight Management
Authors: Teja Pagidi Divya , Veluru Hari
Published: November 2024

Introduction: Obesity is a global health challenge associated with numerous metabolic disorders, including diabetes and cardiovascular disease. With growing interest in natural remedies for weight management, Limonia acidissima L., has garnered attention due to its rich bioactive composition.
Objectives: This systematic review evaluates the anti-obesity potential of Limonia acidissima L., and its key bioactive compounds, including fibres, phytosterols, saponins, polyphenols, flavonoids, and ascorbic acid.
Methods: A comprehensive search of databases such as PubMed, Scopus, and Google Scholar was conducted, focusing on studies published between 2000 and 2023 that investigated the metabolic effects of these compounds on lipid and carbohydrate metabolism, fat absorption, and glucose regulation.
Results: The results demonstrated that Limonia acidissima L., significantly reduced body weight and fat mass, improved lipid profiles, and enhanced insulin sensitivity in both animal and human studies.Phytosterols and saponins played key roles in modulating lipid metabolism, while fibres and polyphenols were found to regulate carbohydrate metabolism and improve glycemic control. Additionally, the synergistic effects of multiple bioactive compounds amplified their collective anti-obesity potential, with few reported adverse effects, suggesting a favourable safety profile. The discussion highlights the multifaceted mechanisms through which Limonia acidissima L., combats obesity, emphasizing its ability to target multiple metabolic pathways simultaneously.While the findings are promising, the need for further large-scale clinical trials to validate these effects in diverse populations is underscored. 
Conclusions: In conclusion, Limonia acidissima L., emerges as a potent natural remedy for obesity management, with strong potential for inclusion in weight loss supplements and functional foods.Its bioactive compounds offer a comprehensive and safe approach to addressing the global obesity epidemic, although further research is needed to establish its long-term efficacy and optimal use.