bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical assessment of stability behaviour in supercritical CO2 based NCLS configured with heater, heat exchanger and isothermal wall as heat source
Authors: THIMMAIAH Srivatsa , WAHIDI Tabish , YADAV Ajay Kumar , MAHALINGAM Arun
Published: April 2023

Three-dimensional numerical analysis is presented in this study to assess the transient and stability behaviour of supercritical CO2 (sCO2) based NCLs configured with three different types of heat sources, i.e., heater, a hot heat exchanger (HHX) and isothermal wall (ISO) at the source, and a cold heat exchanger (CHX) at the sink in all three NCLs. Unsteady threedimensional conservation equations (mass, momentum and energy equations) are solved to assess the transient and stability behaviour of sCO2 mass flow rate, temperature and velocity as a function of time. Further, the effect of pressure on sCO2 mass flow rate is also assessed to compare the loops performance. Performance of the loop has been studied for various heat inputs at the source by keeping constant mass flow rate and temperature at the sink. It is observed that for any boundary condition at the source, the loop experiences some initial disturbances or instabilities before reaching the steady-state. However, the time needed to attain a steady-state varies with the nature of heat input employed at the source. Results show a higher magnitude of instabilities in the Heater-CHX loop than HHX-CHX and ISO-CHX loops, and these instabilities mitigate at a faster rate in the ISO- CHX loop at all levels of heat input and operating pressure of the loop. It is also observed that as loop fluid operating pressure increases, the instability of the system decreases and the loop fluid mass flow rate increases. Further, the Nusselt number in the Heater-CHX loop is more than other loops because of its high turbulent kinetic energy. The findings of this study are validated with the published experimental and numerical data and found a good agreement.
Inflammatory fibrous hyperplasia – A case report
Authors: Kaur Jaspreet , Bala Deepak , Thakur Akshita Singh , Chandel Sarvani , Goel Viniti
Published: April 2023

Gingival enlargement, the currently accepted terminology for an increase in the size of the gingiva, is a common feature of gingival disease. Local and systemic factors influence the gingival conditions of the patient. These factors results in a spectrum of diseases that can be developmental, reactive and inflammatory to neoplastic. In this case report, the history, etiology, clinical features, treatment strategies and preventive protocol of inflammatory hyperplasia are discussed.
Cuentos de encantamiento, de hadas o maravillosos en la provincia de Cuenca
Authors: Gómez Couso Pilar
Published: April 2023

El folclore acompaña al hombre desde su nacimiento y el cuento, especialmente, circula por la mente colectiva de las sociedades, traspasando fronteras, lenguas y culturas desde tiempo inmemorial. Los cuentos de encantamiento, de hadas o maravillosos rescatados de la tradición oral de la provincia de Cuenca y de los que nos ocupamos en este libro, nos acercan a las ideas y a la cultura general de nuestros antepasados, así como a conocer la historia de la evolución, del progreso y de la consolidación cultural y social. Muchos de ellos tienen raíces orientales e incluso más profundas dónde podemos observar fenómenos como el incesto, la antropofagia, demonios, ogros, príncipes y princesas encantadas, etc., y en los que también se pueden entrever detalles de mitos, ritos y tradiciones primitivas. Son el antepasado directo de la literatura. En un principio, la literatura fue oral, por esta razón en el texto, se han reproducido los cuentos en su estado más puro, sin recreaciones literarias que desvirtuaran su originalidad. La afectividad de la palabra hablada traspasa ambientes, sentimientos, la mente y el corazón del hombre. Es el vehículo que nos permite visitar nuestro mundo interior. El cuento, además, es un elemento fundamental en la magnífica tarea de enseñar y aprender. La función pedagógica de los cuentos de encantamiento, de hadas o maravillosos es básica, ya que estos relatos son un enriquecedor medio de educación informal. El hábito de narrar, desafortunadamente, va desapareciendo y con él, los valores que los cuentos de tradición oral encierran. De ahí, la importancia de su recuperación a través de las instituciones educativas sensibilizadas ante este hecho.
AGE DYNAMICS OF REPRODUCTIVE ABILITY AND QUALITY OF AFRICAN CATFISH OFFSPRING UNDER AQUACULTURE CONDITIONS
Authors:   FSBEI HE Ulyanovsk SAU, Lubomirova V.N. , Romanova E.M. ,   FSBEI HE Ulyanovsk SAU, Romanov V.V. ,   FSBEI HE Ulyanovsk SAU
Published: April 2023

The work is devoted to study of influence of African catfish age on reproductive ability and viability of its offspring. The problem is relevant, since the issues of age selection of producers have developed relatively recently in industrial aquaculture and have not been enough studied yet. As for practical fish farming, specialists often face the problem of low quality of fish gametes that are too young or old enough. The aim of the study was a comparative assessment of the age-related variability of reproductive ability and viability of African catfish offspring. African catfish breeders at the age of 12, 24, 48, 60 months were selected for the research, four experimental groups were formed. The parameters of fertility and the quality of reproductive products, linear and weight growth of the offspring, as well as its viability were studied. The results of the study showed age-related changes in the quality of reproductive products, embryos developing from them, and subsequent larvae. Differences in egg fertility, viability of embryos and larvae, and the size of larvae obtained from producers of different ages were established. All parameters indicate that the parents’ age significantly affects the quality of their offspring. As for study of reproductive products of female African catfish of different ages by a number of parameters, such as size and diameter of eggs, certain differences were established in morphometric and physiological parameters of eggs and sperm. The study of the effect of parental age on offspring survival rate in embryonic and postembryonic periods showed that the offspring survival rate of first spawning females was the lowest and increased as the parental individuals matured. The viability of offspring in middle-aged groups of breeders was the highest.
TO SPECIFICATION OF THE FORCE OF A VIBRATORY ROLLER ON THE SOIL
Authors:   FSBEI HE Ulyanovsk SAU, Kurdyumov V. I. , Proshkin V. E. ,   FSBEI HE Ulyanovsk SAU, Proshkin E. N. ,   FSBEI HE Ulyanovsk SAU, Dikov V. V. ,   FSBEI HE Ulyanovsk SAU
Published: April 2023

As a result of the analysis of tillage rollers, it was revealed that the main design feature is to ensure the required specific pressure on the soil, consequently, it is necessary to increase the roller mass per 1 m of the working width, whereas it leads to metal consumption increase of the tool. Based on the obtained data, we developed a fundamentally new design of the vibratory roller, its application will ensure the fulfillment of agrotechnical requirements for soil density with a minimum metal consumption of 70 kg/m. High-quality tillage with a vibratory roller is ensured by a passive drive of unbalancers installed on the axis of a hollow cylinder. To determine the center of mass of the unbalancers, the KOMPAS 3D v 20 program was used, which allows to obtain the desired result with an accuracy of 0.000001 mm. It was revealed in the course of the theoretical study that the unbalancers create vibrations with an amplitude of 0.00008 ... 0.0011 m at a rotation frequency of 800 min-1 due to their displacement in relation to the axis of the vibratory roller. Also, it was revealed that when the unbalancers are displaced in relation to the roller axis, the position of their center of gravity changes by approximately the same value. Concurrently, the specific pressure of the vibratory roller on the soil changes from 732.81 N/m to 1275.28 N/m, increasing by 74% in case of displacement of the unbalancers in relation to the axis of the vibratory roller up to the maximum value of a = 20 mm. Field studies of the proposed roller showed that the quality of soil compaction by the proposed vibratory roller with improved parameters and modes of operation is better than that of the most common rollers, namely, ZKVG-1.4 and ZKKSH-6.
IMMUNOLOGICAL STATUS OF BLOOD AND MILK OF COWS AFTER APPLICATION OF PROBIOTICS
Authors:   FSBEI HE ", Trebukhov A. V. ,   Altai State Agrarian University", Utts S. A. ,   FSBEI HE "Altai State Agrarian University"
Published: April 2023

Among the main tasks of cattle breeding is creation of conditions for obtaining healthy young animals, which will ensure high level of productivity in the future. Nowadays, interest in probiotic products is growing in countries around the world. Probiotics help to reduce diseases of livestock, improve digestion, metabolism, increase animal productivity, and maintain the immunological status. Vetom series probiotics are widely used in this industry. These products have an extensive range of actions, one of which is correction of immunobiochemical status. The aim of our study was to study the effect of Vetom 1.2 probiotics on immunological status of blood and milk. Scientific and economic experiment was carried out at AO "Uchkhoz" Prigorodnoe ", Barnaul, on black-and-white cows in the autumn-winter period. The manufacturer of "Vetom 1.2" probiotic preparation is OOO NPF "Research Center", Novosibirsk Region, Koltsovo v. When analyzing the results of the studies, we found: 1. Increase of parameters during the study period: carotene by 27.4%, retinol and tocopherol by 26.5% and 16.2%, respectively, gamma globulin by 15.8%, albumin by 10 .6%. 2. Increase of immunoglobulins in blood serum of cows in the experimental group compared to the control group: albumin by 14.4%; alpha, beta, gamma globulin by 16.3%, 13.7%, 17.8%, respectively. 3. It was found that the level of immunoglobulins in colostrum was higher by 31.4% in the experimental group of cows on the first day of lactation, on the second day by 14.1% compared to the control group. Based on the obtained results, the following conclusions were made: 1. "Vetom 1.2" has a positive effect on dynamics of immunological status of cow blood. 2. The probiotics helps to increase the level of immunoglobulins in the colostrum of cows.
QUALITY OF FOOD EGGS IN CASE OF DIFFERENT DURATION OF FEEDING PHASES OF LAYING HENS
Authors:   FSBEI HE Izhevsk State Agricultural Academy, Astrakhantsev A. A. , Perevozchikov M. A. ,   FSBEI HE Izhevsk State Agricultural Academy, Naumova V. V. ,   FSBEI HE Ulyanovsk SAU
Published: April 2023

Quality parameters of food eggs are influenced by paratypic factors and, firstly, by feeding factor. The issues of maintaining appropriate quality characteristics of eggs while improving poultry feeding programs seem to be relevant. In this regard, the aim of our study was to evaluate quality parameters of food eggs of Lohmann LSL Classic cross hens, depending on application time of three-phase compound feed in poultry feeding. The study was carried out at OOO Varaksino Poultry Farm, Zaviyalovsky District, Udmurt Republic. Three groups of laying hens were formed for the study, by the method of analogue groups, each of which consisted of 3 parts of birds. The groups differed by time of application of compound feed recipes of three phases. Morphological analysis of food eggs was carried out by instrumental method, the components were weighed on a VK-600 electronic scales. Biophysical parameters of the constituent components of the eggs were determined using a digital ovoscope DE 16000. The analysis of the qualitative characteristics of eggs at the age of 52 and 72 weeks did not reveal a significant difference between the groups in terms of morphological and biophysical parameters, except for yolk diameter at 52 weeks. The diameter of the egg yolk in the third group was significantly less (P ≥ 0.95) than the same value in the second group by 2.6%. Consequently, the factor of using different phase durations in feeding of laying hens did not have a significant effect on qualitative characteristics of food eggs. Obviously, final effectiveness of application of the studied feeding factor will depend on the level of egg production and the cost of feeds.
RESEARCH RESULTS OF DESIGN PARAMETER INFLUENCE OF A TORSION-PIN SOWING MACHINE ON DOSING UNIFORMITY OF HARD-RUNNING SEEDS
Authors:   FSBEI HE Samara State Agrarian University, Kryuchin N. P. , Isaev Yu. M. ,   FSBEI HE Ulyanovsk SAU, Artamonova O. A. ,   1FSBEI HE Samara State Agrarian University
Published: April 2023

The purpose of the study is to increase uniformity of sowing of difficult-to-flow seeds by substantiating the design parameters of the torsion-pin sowing machine. Sowing is crucial technological operation in ensuring high yields of agricultural crops. Concurrently, sowing of legumes is associated with certain difficulties due to increased requirements of these crops to the amount of moisture at initial stage of development. One of the most effective ways to eliminate moisture deficiency is pre-sowing soaking. However, the existing sowing machines are not capable of sowing soaked seed materials with high quality parameters. To solve the problem of sowing difficult-to-flow seeds of legumes, a torsion-pin sowing machine was developed. Laboratory studies of the developed sowing machine were carried out to assess the influence of its design parameters on uniformity of longitudinal distribution of seeds. The results of experimental studies on assessing the quality of seeding of hard-to-flow seeds of legumes with a torsion-pin sowing machine showed that uniformity of longitudinal distribution of seeds increased in case of installing movable pins. Under these circumstances, the highest uniformity of seed sowing, both of sweet clover and sainfoin, amounted respectively to 39...46% and 45...51%, of the variation coefficient in the mass of seeds in one-centimeter cells, the highest uniformity was obtained in case of equipping the sowing machine with four torsion-pin groups with three movable 15 mm high pins.
ADVANTAGEOUS SOURCES OF BREEDING AND VALUABLE TRAITS AMONG GRAPE VARIETIES OF ANAPA AMPELOGRAPHIC COLLECTION
Authors:   Anapa Zonal Experimental Station of Viticulture and Winemaking - a branch of the Federal State Budgetary Scientific Institution North Caucasian Federal Scientific Center of Horticulture, Viticulture, Winemaking, Gorbunov I.V.
Published: April 2023

Genetic collection of Anapa Zonal Experimental Station of Viticulture and Winemaking includes samples of grape culture of various ecological and geographical origin, which are successfully used in breeding work of this experimental station and other scientific institutions. Active search for new sources and donors of economically valuable traits and resistance to biotic and abiotic stressors is carried out in ampelographic collection of genetic resources of Anapa Zonal Experimental Station of Viticulture and Winemaking. This article contains main results of scientific research over the past three years related to the study and identification of new sources of economically valuable traits and resistance to biotic and abiotic environmental factors among the varieties of the ampelographic collection of Anapa Zonal Experimental Station for Viticulture and Winemaking - a branch of the Federal State Budgetary Scientific Institution of the North Caucasus Federal Scientific Center of Horticulture, Viticulture, Winemaking. The objects of the research were grape varieties of various ecological and geographical origin from the gene pool of Anapa ampelographic collection. The study used traditional and improved breeding programs and methods. In the course of long-term research work, 15 sources of selection-valuable traits were identified among the grape varieties of Anapa Zonal Experimental Station of Viticulture and Winemaking, which are used in crosses to create new varieties. These source varieties are annually investigated for phenological and agrobiological characteristics, which have consistently high parametres. As for table grape direction, such varieties as Strashenskiy, Doch Nimranga, Pamyati Dombkovskaya, Arcadia and Olimpiada have the highest fruiting coefficient and yield. Source varieties that annually have high parametres of sugar accumulation - an important feature for winemaking - Bastardo, White Muscat, Rkatsiteli Magaracha, Pierrel are actively used in hybridization to produce new high-quality grape varieties.
Ganoderma lucidum Polysaccharide Peptide Reduces Oxidative Stress and Improves Renal Function in Patient with Cardiometabolic Syndrome
Authors: Wardhani Syanindita Puspa , Nadliroh Khilmi Ainun , Aishaqeena Al Mazida Fauzil , Sonia Fahriza Abid , Suryo Adji Achmad Guntur Hermawan , Hanim Intan Masyfufah , Hidayatulloh Rizkia Milladina , Rahimah Anna Fuji , Rizal Ardian , Sugita Peter , Sandra Ferry , Sargowo Djanggan
Published: April 2023

BACKGROUND: Cardiometabolic syndrome is a risk factor for the development of diseases related to cardiovascular disease and decreased renal function. Ganoderma lucidum polysaccharide peptide (GLPP) has been reported to have anti-inflammatory and antioxidant properties. The current study was conducted to investigate the role of GLPP in inflammatory, oxidative stress and renal function markers of cardiometabolic subjects.METHODS: A randomized double-blinded perspective control trial with pre-post design was conducted. Cardiometabolic syndrome subjects were treated with placebo or GLPP for 60 days. Blood serum was collected from each subject before the first capsule consumption and one day after the last capsule consumption. Serum tumor necrosis factor (TNF)-α, high-sensitivity-C-Reactive Protein (hs-CRP) and malondialdehyde (MDA) levels were measured using enzyme-linked immunosorbent assay, while superoxide dismutase (SOD) level was measured using colorimetric assay. Serum urea and creatinine levels were measured using a clinical analyzer. The Cockroft-Gault formula was used to calculate estimated glomerular filtration rate (eGFR).RESULTS: Compared with the control group, the MDA level was significantly reduced, while the SOD level was significantly increased in the GLPP treatment group. Furthermore, serum urea and creatinine were lowered, while eGFR was increased in the GLPP treatment group.CONCLUSION: Treatment of GLPP for 60 days could be beneficial for lowering oxidative stress and improving renal function of patients with cardiometabolic syndrome.KEYWORDS: Ganoderma lucidum, cardiometabolic syndrome, inflammation, oxidative stress, renal function
Curcumin Analogs PGV-1 and CCA-1.1 Induce Cell Cycle Arrest in Human Hepatocellular Carcinoma Cells with Overexpressed MYCN
Authors: Moordiani Moordiani , Novitasari Dhania , Susidarti Ratna Asmah , Ikawati Muthi' , Kato Jun-ya , Meiyanto Edy
Published: April 2023

BACKGROUND: Liver cancer is the third leading mortality in cancer. Curcumin shows effective anticancer potency against various cancer including liver cancer. The synthesized curcumin analog compounds Pentagamavunone-1 (PGV-1) and Chemoprevention Curcumin Analog-1.1 (CCA-1.1) have been well studied in breast, leukemia, and colon cancer cells with better potency than curcumin itself, yet their cytotoxic activities were not known in liver cancer cells. Thus, this study was conducted to elevate the anticancer effect of these curcumin analogs against hepatocellular carcinoma (HCC) cells in vitro, specifically in MYCN-expressing cells, based on its cellular physiology.METHODS: JHH-7 cells were used as the HCC cell model with high expression of MYCN. The viability of the cells was observed using trypan blue exclusion method while cell cycle profile and intracellular reactive oxygen species (ROS) levels were quantified by means of flow cytometry. Chromosomal staining with Hoechst was applied to determine the cell cycle arrest phase, whilst X-gal staining was used to assess the cellular senescence activity.RESULTS: The result of current study presented that the growth inhibitory activity of PGV-1 as well as CCA-1.1 in JHH-7 cells was associated with the cell cycle arrest and cellular senescence. Both curcumin analogs PGV-1 and CCA-1.1 ultimately induced mitotic arrest (p<0.001) better than curcumin. Moreover, PGV-1 and CCA-1.1 similarly increased the senescent cells that partly mediated through ROS elevation. The transcription level of MYCN was not altered upon treatment with curcumin and its analogs in JHH-7 cells, suggesting that molecular mechanism of the inhibitory effect was independent from MYCN signaling.CONCLUSION: Taken together, these observations revealed that both PGV-1 and CCA-1.1 potentially serve as multi-targeted curcumin-based compounds and lead to promising anti-hepatocellular cancer agents.KEYWORDS: Curcumin analogs, hepatocellular carcinoma, mitotic arrest, MYCN
SARS-CoV-2 Neutralization Assay System using Pseudo-lentivirus
Authors: Armimi Anastasia , Syuaib Afina Firdaus , Vanya Katherine , Tan Marselina Irasonia , Natalia Dessy , Chen David Virya , Ono Chikako , Matsuura Yoshiharu , Artarini Anita , Giri-Rachman Ernawati Arifin
Published: April 2023

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects humans' lower respiratory tracts and causes coronavirus disease-2019 (COVID-19). Neutralizing antibodies is one of the adaptive immune system responses that can reduce SARS-CoV-2 infection. This study aimed to develop a SARS-CoV-2 neutralization assay system using pseudo-lentivirus.METHODS: The plasmid used for pseudo-lentivirus production was characterized using restriction analysis. The gene encoding for SARS-CoV-2 spike protein was confirmed using sequencing. The transfection pseudo-lentivirus optimal condition was determined by choosing the transfection reagents and adding centrifugation step. Optimal pseudo-lentivirus infection was analysed using fluorescent assay and luciferase assay. The optimal condition of pseudo-lentivirus infection was determined by the target cell type and the number of pseudo-lentiviruses used for neutralization test. SARS-CoV-2 pseudo-lentivirus was used to detect neutralizing antibodies from serum samples.RESULTS: The plasmid used for pseudo-lentivirus production was characterized and confirmed to have no mutations. Lipofectamine 2000 reagent generated pseudo-lentivirus with a higher ability to infect target cells, as indicated by a percentage green fluorescent protein (GFP) of 12.68%. Pseudo-lentivirus centrifuged obtained more stable results in luciferase expression. Optimal pseudo-lentivirus infection conditions were obtained using puromycin-selected HEK 293T-ACE2 cells as target cells. The number of pseudo-lentiviruses used in the neutralization assay system was multiplicity of infection (MOI) 0.075. Serum A samples with a 1:10 dilution had the highest neutralizing antibody activity.CONCLUSION: This study shows that SARS-CoV-2 neutralization assay system using pseudo-lentivirus successfully detected neutralizing antibodies in human serum, which were indicated by a decrease in the percentage of pseudo-lentivirus infections.KEYWORDS: COVID-19, neutralizing antibody, neutralization assay, pseudo-lentivirus, SARS-COV-2
Las transformaciones del Derecho objetivo ante el fenómeno jurídico-global
Authors: Iglesias Sevillano Héctor
Published: April 2023

En el presente trabajo proponemos una revaluación del concepto de Derecho objetivo a la vista del fenómeno jurídico-global. No se trata, naturalmente, de “redefinir” el Derecho, sino sencillamente de explicar cómo la globalidad transforma su contenido desde las categorías clásicas hasta el moderno pluralismo. Para describir el paradigma actual de la normatividad examinaremos brevemente los rasgos que se han atribuido tradicionalmente al Derecho y los contrapondremos a su fenomenología global. Para ello construiremos la hipótesis de que el fenómeno jurídico global es, exactamente, un pluralismo, pero no un pluralismo normativo en el vacío de normas independientes e incomunicadas, sino un conjunto variado y diverso de sistemas normativos que se relacionan permanentemente entre sí.
El rol del holismo y del contextualismo en la interpretación constitucional. Consideraciones a la luz de las categorías teóricas de la tesis de Duhem-Quine
Authors: Zezza Michele
Published: April 2023

El estudio tiene como objetivo reflexionar sobre el condicionamiento ejercido por el contexto externo en la interpretación jurídica de las disposiciones constitucionales que reconocen derechos fundamentales. Para ello, se retoman algunas indicaciones metodológicas procedentes del ámbito de la llamada “tesis de Duhem-Quine”. No se pretende teorizar la existencia de una relación de identidad entre la filosofía de la física y la filosofía del lenguaje, por un lado, y el plano jurídico, por el otro, sino más bien la posibilidad de una transposición analógica, en el marco de la interpretación jurídica, de algunas adquisiciones esenciales del holismo epistemológico y semántico.
El enfoque de orientación sexual e identidad de género en la restitución de tierras en Colombia
Authors: Duque Roldán Juan Sebastián
Published: April 2023

La Ley 1448 de 2011 creó un procedimiento de restitución de tierras que busca reparar a las víctimas del desplazamiento forzado en Colombia, y que debe implementar un enfoque diferencial que beneficie a grupos poblacionales históricamente discriminados, entre ellos las personas LGTB. Por ello, se pretende analizar en qué ha consistido la implementación del enfoque de orientación sexual e identidad de género en estos procedimientos. Se da inicio con una breve conceptualización acerca de este enfoque diferencial, y luego se aborda el marco jurídico de protección de las personas LGTB en situación de desplazamiento. Después, se estudian los problemas y deficiencias en la implementación de este enfoque en los procesos de atención, restitución, fase posfallo, microfocalización y participación de víctimas. Por último, se formulan recomendaciones que buscan superar las irregularidades observadas en cada uno.
La mayor onerosidad fortuita en el contrato de obra pública
Authors: Arancibia Mattar Jaime
Published: April 2023

Este trabajo procura responder la pregunta acerca de qué parte del contrato de obra pública debe asumir la mayor onerosidad sobreviniente causada por un hecho fortuito. Para ese efecto es preciso determinar la modalidad específica de restauración del equilibrio perdido por ese evento, lo que obliga a distinguir si la normativa específica o el contrato han regulado un régimen de compensación de tales sobrecostos. En tal caso, como es obvio, deberá estarse a lo suscrito. Sin embargo, ante la omisión normativa o consensual sobre el particular, corresponde analizar la aplicación de la doctrina de la imprevisión. Al respecto, la jurisprudencia administrativa chilena ha rechazado la aplicación de la teoría de la imprevisión por falta de normas legales y reglamentarias que la prevean. Este trabajo es crítico de esa doctrina porque el silencio legal determina la vigencia directa de la norma constitucional sobre igualdad distributiva y, por tanto, del deber social de compensar cualquier desequilibrio económico inimputable al constructor.
Análisis económico de los contratos sobre órganos humanos
Authors: Castro Azócar Felipe Javier
Published: April 2023

El presente trabajo elabora una revisión de los contratos sobre órganos humanos desde el punto de vista del Análisis Económico del Derecho. Se hace uso de las herramientas propias del derecho y la economía, se adopta una posición crítica en torno la concepción y el marco legal dominante en el mundo sobre esta materia, para con ello realizar un análisis de la legalización de las transacciones sobre órganos a través del diseño de un mercado regulado, comentando las potenciales ventajas que esta traería por sobre la absoluta prohibición.
Una introducción a la toma de decisiones colectivas
Authors: Ortega Urbina José Manuel
Published: April 2023

El objetivo de este artículo es presentar de manera sucinta la Teoría de la elección social y algunas de sus implicaciones. Kenneth Arrow, su fundador, no cree en la distinción empobrecedora entre economía y ética, hace explícita la reflexión filosófica sobre la intersección entre ética, política y economía. Primeramente, se abordan algunas cuestiones de la agregación de preferencias individuales en una función de bienestar social; el siguiente apartado analiza la distinción entre valores individuales y colectivos que juegan un papel central en el proceso de elección. Después tratamos el problema de la acción colectiva y los límites de los sistemas de votación; y finalmente se enuncian algunas conclusiones generales.
Modelo Dinâmico de Sistemas de Armazenamento de Energia em Baterias para Provimento de Serviços Ancilares
Authors: Torres Pedro F. , Figueiredo Gilberto , Almeida Marcelo P. , Manito Alex R. A. , Almeida Neto José C. S. , Cassares Mauricio A. R. , Zilles Roberto
Published: April 2023

A prestação de serviços ancilares (SA) vem sendo cada vez mais valorada em um contexto de inserção em larga escala de fontes não despacháveis, dada a necessidade de garantir a operação segura e confiável dos sistemas de potência. Nesse sentido, Sistemas de Armazenamento de Energia em Baterias (SAEB) dispõem de flexibilidade operacional para prover diferentes tipos de SA, podendo ser considerados como alternativa no planejamento em diversas situações a nível de transmissão e distribuição. Este artigo apresenta a aplicação de um modelo dinâmico para simulação de transitórios eletromecânicos implementado em ambiente ANATEM, considerando os requisitos de modelagem estabelecidos pelo Operador Nacional do Sistema (ONS).
Analysis of cavern and narrows of drilling wells in Azerbaijan fields
Authors:   Azerbaijan State Oil and Industry University, Ibrahimov Rafiq S. , Bahshaliyeva Shirin O. ,   Azerbaijan State Oil and Industry University, Efendiyeva Leyla ,   Azerbaijan State Oil and Industry University, Ibrahimov Zaur R. ,   Bаker Hughes, Azerbaijan
Published: April 2023

An analysis of numerous well data from the Karabagly and Kursangi monocline regions in Azerbaijan showed that the main reasons of natural curvature are structural and geological conditions of wells. In contrast to a number of fields where wells are naturally bent in only one direction under the combination of geological, technical and technological factors, there are three other directions in the areas of the Karabagly and Kursangi monocline. It is suggested that according to the proposed technology, drilling intervals are minimized by an assembly with a crooked sub, and the technical and economic parameters of drilling are improved. With an increase in the content of alkaline reagents in the drilling fluid, despite a significant decrease in the absolute value of fluid loss, the likelihood of complications increases. One of the main requirements for maintaining the integrity and stability of the wellbore is the prevention of filtration. This condition imposes a certain limitation on the amount of fluid loss in drilling fluids. In drilling practice, it is necessary to strive not only to minimize the fluid loss of flushing fluids, but also to the qualitative and quantitative evaluate various additives that slow down their physical and chemical impact on the rocks forming the walls of the well.
ТРУДОВАЯ АКТИВНОСТЬ РОССИЯН В ПЕРИОД ПЕРВЫХ ВОЛН ПАНДЕМИИ COVID-19: ВЗГЛЯД НАЕМНЫХ РАБОТНИКОВ ВОЛОГОДСКОЙ ОБЛАСТИ
Authors: Попов Андрей Васильевич
Published: April 2023

Актуальность. Последствия пандемии коронавируса COVID-19 остаются важным направлением исследований не только в эпидемиологии, но и в общественных науках. Введение локдауна в большинстве стран мира в 2020 г. спровоцировало серьезные социально-экономические потрясения, которые затронули все сферы жизнедеятельности. Цель – анализ изменений в трудовой активности россиян в период пандемии COVID-19. Материалы и методы: информационную базу составили данные мониторинга качества трудового потенциала населения Вологодской области за 2018−2020 гг. Для формирования более однородной выборки объект исследования был сужен до наемных работников. При проведении сравнительного статистического анализа использовались традиционные методы, одним из которых выступил метод частотного распределения. Результаты и выводы: мониторинговые данные показали, что продолжительность рабочего времени по основному месту работы не претерпела существенных изменений во время первых волн пандемии. При этом намного чаще люди стали прибегать к вторичной занятости и нерегламентированной работе во внеурочное время. Заметнее всего последствия пандемии отразились на напряженности трудового процесса, что обернулось необходимостью сильнее «выкладываться» на работе. Это касается всех качеств трудового потенциала, рассмотренных в исследовании, однако сильнее всего возросла нагрузка на физическое здоровье. По мнению опрошенных, резервы повышения продуктивности труда связаны, прежде всего, с модернизацией оборудования и совершенствованием производственного процесса. В заключении подчеркивается значимость научного направления в свете санкционного давления, вызванного геополитической нестабильностью в 2022 г. Проведенный анализ позволяет по-новому взглянуть на внешнюю стабильность сферы социальнотрудовых отношений в России и очертить спектр проблемных вопросов, игнорирование которых в сложившихся условиях может обернуться серьезными социально-экономическими последствиями. Перспективы дальнейшего исследования видятся в раскрытии особенностей трудовой активности работников различных отраслей экономики.
СОСТОЯНИЕ СТРУКТУРЫ ПОТРЕБЛЕНИЯ ПРОДУКТОВ ПИТАНИЯ НАСЕЛЕНИЕМ СВЕРДЛОВСКОЙ ОБЛАСТИ
Authors: Таскин Фёдор Александрович
Published: April 2023

Актуальность исследования связана с тем, что неправильное и несбалансированное питание увеличивает риск возникновения многих социально значимых заболеваний человека, влияет на социально-экономическое развитие региона. Цель статьи − анализ структуры потребления продуктов питания населением Свердловской области. Методы: сопоставительный анализ, статистический анализ и специальные методы визуализации данных. Результаты: рассмотрена структура потребления продуктов питания в домашних хозяйствах в Уральском федеральном округе за 2021 г.; сопоставлено потребление продуктов питания населением Свердловской области с другими регионами Уральского федерального округа; проанализировано потребление основных групп продуктов питания населением в Российской Федерации и Свердловской области, а также проведено сравнение фактического потребления с рекомендуемыми нормами за 2018–2021 гг.; оценен уровень потребления продуктов питания населением региона в городской и сельской местностях; описано влияние отдельных групп продуктов питания на здоровье человека; рассчитан уровень самообеспечения Свердловской области основными видами сельскохозяйственной продукции. Сформулирован вывод о несоответствии потребления продуктов питания населением Свердловской области рекомендуемым нормам, о существовании общих проблем в потреблении продуктов питания домашними хозяйствами в городской и сельской местностях, при этом выявлен факт наличия более рационального питания у городского населения по сравнению с сельским. Отмечено, что Свердловская область не может полностью обеспечить потребность региона в ряде основных продуктов животноводства и растениеводства. Сформулированы рекомендации по достижению рациональной структуры питания населения Свердловской области.
Identification and Validation of Pedochemical and Fertility Indices of Soils Influencing Maize (Zea mays) Crop Production in the Rain Forest Agro-ecology of Nigeria
Authors: Akpan Joyce F , Nwanyieze Njoku R. , O Omeke Joel , Grace Stephen-Oleka O. , Umunnakwe, Okechukwu C. , Reagan Agbor B. , Ubi Godwin M.
Published: April 2023

Background: The soil is a fundamental natural resource of any nation hence proper assessment of the kind and extent of this resource is prerequisite to its improvement and rational use. Method: Random sampling technique was used to collect soils from each of the 18 LGAs of Cross River State, Nigeria and each separated into two parts. One part was used for the cultivation of local maize while the other part of soil was analysed for pedochemical properties and fertility indices. Result: The results reveal that organic carbon ranged from 1.40 g/kg3 to 2.84 g/kg3. Available Phosphorus varied from 3.31 mg/kg to 29.24 mg/kg. The value of total nitrogen varied from 0.11 g/kg3 to 0.24 g/kg3. Cation exchange capacity (CEC) also varied from 7.01 Cmol/kg3 to 12.01 Cmol/kg3. The soils across the agroecology were more acidic 5.00 to less acidic 0.61. Boron varied from 0.52 mg/kg3 to 2.01 mg/kg3 while Zinc also ranged from 1.93 mg/kg3 to 5.0 mg/kg3. The results also show that 33.33% of the soils were rated high, medium and low for available phosphorus. It was identified that total nitrogen nutrient fertility ratings for the soils was 77.78% high fertility ratings and 22.22% medium fertility ratings. Results identified organic carbon fertility rating was of high fertility rating of 72.23% while 27.67% medium rating was identified for organic carbon content. Ten (10) principal components (PC) were identified to contribute to the total 100% support for maize crop production in the study area.
DETERMINANT OF CONSUMER DECISION ON ISLAMIC BANKING
Authors: Sari Dian Novita , Siswanto Siswanto , Maksum Ikhsan , Abdani Fadlil , Khan Ryan Basith Fasih , Retnasih Nora Ria , Setiani Setiani , Masyhuri Masyhuri
Published: April 2023

This study investigates the determinant of customer decisions in Islamic banks' savings: motivation, promotion, and religiosity. Trust variable as a form of research novelty as a mediation. This study uses a quantitative approach with explanatory research. Using purposive sampling, the sample is 95 Islamic bank customers in Nganjuk City, East Java. Data are analyzed using structural equation modeling with Smartpls software. This research generally describes the factors that can improve customer decisions in opening savings at Islamic banks, such as motivation, promotion, and religiosity. These three factors in this study proved that only direct motivation could improve customer decisions. The result means that the other two factors need a mediating variable in the form of customer trust in Islamic banks regarding the safety of money stored and guarantees free from usury. These findings can be a suggestion for the management of Islamic banks to do promotions more often, meaning that what has been done now is still inferior to conventional banks in promotion.
ZAKAT, INFAQ AND SHADAQAH (ZIS) DIGITALIZATION: A CASE STUDY USING TECHNOLOGY ORGANIZATION ENVIRONMENT FRAMEWORK
Authors: Aligarh Frank , Falikhatun Falikhatun , Nugroho Arif
Published: April 2023

Technological disruption has changed the process of collecting zakat, infaq, and shodaqoh (ZIS). These changes can pose both threats and opportunities for ZIS institutions. This study aims to describe the acceptability of ZIS institutional technology from a Technology-Organization-Environment (TOE) perspective. This research is qualitative research with a case study approach. This study uses a data collection method consisting of observation, in-depth interviews, and documentation. Using in-person interviews and via cell phone. The subject of this research is the head of the ZIS institution. The results of the study state that all ZIS institutions have made technological innovations in collecting zakat, infaq, and shodaqoh. The existence of limited human resources and organizations' low acceptance of digital platforms are obstacles to not maximizing digital platforms' use. Strong encouragement from muzakki, government, and digital platform-based ZIS institutions has inspired them to develop technological innovations that suit their needs. This research contributes practically to ZIS institutions that the map of muzakki and donors has begun to change so that technological readiness is the key to the sustainability of ZIS institutions.
Financial Advice Use and Saving for Children’s College Education: A Propensity Score Matching Approach
Authors: Korankye Thomas , Pearson Blain , Salehi Hossein
Published: April 2023

This study examines the effects of financial advice on college-saving decisions using data sets from the 2009 and 2012 U.S. National Financial Capability Study. After controlling for self-selection bias through propensity score matching, the findings show that receiving financial advice is associated positively with the likelihood of saving for children’s college education. Other findings reveal that seeking specific types of financial advice relating to savings/investment, insurance, and tax planning is positively associated with a household’s decision to allocate money for their children’s postsecondary education. The ensuing discussion highlights that policies incentivizing households to seek financial advice could promote college savings and contribute to reduction in student loan dependence.
Rancang Bangun Mesin Pencucian Garam Dua Tingkat Skala Kecil
Authors: Siregar Tika Hafzara
Published: April 2023

Kondisi perekonomian petani garam dan kualitas garam rakyat kerap kali membuat petani garam berada di posisi tawar yang lemah, sehingga harga jual garam di tingkat petani rendah. Mesin pengolahan garam konsumsi skala kecil perlu dirancang untuk meningkatkan nilai dari garam sehingga kesejahteraan petani garam dapat meningkat. Penelitian ini bertujuan untuk merancang mesin pencucian garam krosok yang bertujuan untuk meningkatkan kandungan NaCl dan menghilangkan zat-zat pengotor lain seperti CaSO4, MgSO4, MgCl2 dan lain-lain. Mesin dirancang menggunakan sistem pemutaran dengan mempertahankan nilai baume dari air tua pencuci garam pada nilai 25-28. Mesin dilengkapi dengan sensor baume untuk mengontrol nilai baume air tua. Variable lama waktu pencucian divariasikan untuk menghasilkan  kualitas garam terbaik. Penelitian ini sudah merancang mesin pencucian garam dua tingkat dengan sistem pengontolan nilai 0Be  yang dapat mencuci garam dengan air tua berkapasitas 50kg. Mesin ini melakukan 2 kali proses pencucian garam. Alat ini berpenggerak motor listrik 1,5 HP untuk mengaduk garam krosok bersama air tua sehingga dapat melarutkan bahan-bahan pengotor dan mempertahankan NaCl dalam bentuk kristal. Kemurnian NaCl garam krosok meningkat sebesar  7,5% setelah mengalami pencucian selama 20 menit.
Aktivitas Antikanker Nanokapsul Ekstrak Mengkudu (Morinda citrifolia L.) dengan Pengujian in Vivo pada Fibrosarkoma Mencit Jantan Balb/c
Authors: Aisyah Nur , Ningtias Lulus Kartika , Marchianti Ancah Caesarina Novi , Piluharto Bambang , Cahyaningrum Deltaningtyas Tri , Retnowati Naning , Diniyah Nurud , Iswahyono Iswahyono , Fauziah Riska Rian
Published: April 2023

Noni (Morinda citrifolia L.) is one of the many herbs which known as an anticancer agent. Nanoencapsulated form of noni extracts could help the body absorption and able to inhibit the proliferation of cancer cells in vitro. This study was conducted to examine the anticancer activity of nanoencapsulated noni extracts in vivo as the anti-proliferation agent of cancer cells. Noni extract was obtained by maceration method using water as a solvent. The nanocapsule of noni extracts was made using the ionic gelation method by magnetic stirrer with the speed of 1500 rpm. In vivo anticancer activity test was conducted in Balb/c male mice by comparing the treatment of nanoencapsulation noni extracts and non-encapsulated extracts. The result showed that the nanoencapsulated noni extracts have a particle size of 27-59 nm. Percent of inhibition of nanocapsule on cancer cells (specifically on fibrosarcoma of Balb/c male mice) were equal to 54.75% (P2), while non-encapsulated is 49.72% (P1). Nanocapsule of noni extracts has anticancer activity better than non-encapsulated form on fibrosarcoma of Balb/c male mice.

Keywords: anticancer, nanoencapsulation, noni extract
Desain Kemasan Minuman Sari Buah Mengkudu (Morinda citrifolia) untuk Meningkatkan Pemasaran di UD Manjur Makmur
Authors: Wulandari Anita , Cahyani Wahyu Kanti Dwi , Widodo Richardus , Widyalasmono R. Paulus
Published: April 2023

One of the variant of Morinda citrifolia fruit drink is called noni juice and known as Noni Super Power’s brand name at UD Manjur Makmur. This beverage is naturally fermented by spontaneous fermentation at 28-30°C during six months in a bottle that has been cleaned and tightly closed. During the marketing process to consumers, the design packaging of noni drink is needed to attract consumers buying. Meanwhile, the primary packaging of noni juice at UD Manjur Makmur is less attractive to consumers, there is also no secondary and tertiary packaging and it became the product's packaging weakness. So, label and packaging for noni juice products are needed to design to promote product identity and display product visuals to raise the consumers’ interest. This study was conducted to solve these problems. In this research, benchmarking of products, the Guide on Labeling of Processed Food Agency for National Drug and Food Control (2020), and the observation, imitation, modify methodology were applied. This research resulted in the design of primary, secondary, and tertiary packaging for noni fruit juice drinks. Following the benchmarking, the guide of processed food label requirements, and evaluating the packaging and labels (2020), the new design packaging and labels were better than before. As packaging of noni juice, plastic bottles with new design label are used for primary packaging, followed by rectangles (boxes) made from samson paper (size of 6,3 × 6,3 × 18 cm) for secondary packaging, and cardboard boxes made from corrugate (size of 30 × 20 × 40 cm) for tertiary packaging. Furthermore, the new design packaging (especially tertiary packaging) can accommodate a large amount of noni juice bottles during the marketing and distribution of its product.

Keywords: consumers’ interest, noni juice, label, packaging
Analysis of the Characteristics of the Medical Industry and the Determinants of Investment: Focusing on South Korea-U.S. FDI
Authors:   IAGBT, Ha Young-Kyou , Lee Chang-Joon
Published: April 2023

Purpose - This study analyzes the current status, background, and factors that affect the maintenance and success of the South Korea-U.S. medical foreign direct investment (FDI), which has been rapidly increasing since the COVID-19 pandemic.
Design/Methodology/Approach - This study was conducted from the perspective of the United States (U.S.), the host country of investment. A panel analysis was conducted with the 10-year data of economic and logistics factors of 30 major U.S. states. The independent variables were Gross domestic product (GDP), payroll, and employment rate, and logistics factors were the number of logistics bases and amount of investment. The dependent variable was the amount of South Korea-U.S. medical FDI.
Findings - The empirical analysis revealed that GDP, payroll, and number of airports had significant positive effects on FDI. The medical industry is a typical high value-added process industry, and the economic power of the host region and payroll to employ excellent workers were key variables. Air transport infrastructure was also a prominent factor due to the nature of pharmaceutical drugs.
Research Implications - The analysis results show the typical characteristics of the medical industry. The results and implications can guide future medical FDI in a more effective direction.