bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Evaluation of qPCR Detection Method and Zn-MgO/Alginate Active Packaging for Controlling Listeria monocytogenes Contamination in Cold-Smoked Salmon
Authors: Vizzini Priya , Beltrame Elena , Zanet Valentina , Vidic Jasmina , Manzano Marisa
Published: September 2020

To answer to food industry requests to monitor the presence of L. monocytogenes in cold-smoked salmon samples and to extend their shelf-life, a qPCR protocol for the detection of L. monocytogenes, and an antibacterial active packaging reinforced with zinc magnesium oxide nanoparticles (Zn-MgO NPs) were developed. The qPCR allowed the sensitive and easy detection of L. monocytogenes in naturally contaminated samples, with specificity in full agreement with the standard methods. The halo diffusion study indicated a high antibacterial efficiency of 1 mg/mL Zn-MgO NPs against L. monocytogenes, while the flow cytometry showed only moderate cytotoxicity of the nanoparticles towards mammalian cells at a concentration above 1 mg/mL. Thus, the novel active packaging was developed by using 1 mg/mL of Zn-MgO NPs to reinforce the alginate film. Cold-smoked salmon samples inoculated with L. monocytogenes and air-packed with the Zn-MgO NPs-alginate nanobiocomposite film showed no bacterial proliferation at 4 °C during 4 days. In the same condition, L. monocytogenes growth in control contaminated samples packed with alginate film alone. Our results suggest that Zn-MgO nanoparticles can extend the shelf-life of cold-smoked salmon samples.
On Some Formulas for the k-Analogue of Appell Functions and Generating Relations via k-Fractional Derivative
Authors: Gürel Yılmaz Övgü , Aktaş Rabia , Taşdelen Fatma
Published: September 2020

Our present investigation is mainly based on the k-hypergeometric functions which are constructed by making use of the Pochhammer k-symbol in Diaz et al. 2007, which are one of the vital generalizations of hypergeometric functions. In this study, we focus on the k-analogues of F1Appell function introduced by Mubeen et al. 2015 and the k-generalizations of F2 and F3 Appell functions indicated in Kıymaz et al. 2017. we present some important transformation formulas and some reduction formulas which show close relation not only with k-Appell functions but also with k-hypergeometric functions. Employing the theory of Riemann–Liouville k-fractional derivative from Rahman et al. 2020, and using the relations which we consider in this paper, we acquire linear and bilinear generating relations for k-analogue of hypergeometric functions and Appell functions.
Dreaming of Perfect Data: Characterizing Noise in Archaeo-Geophysical Measurements
Authors: Schmidt Armin , Dabas Michel , Sarris Apostolos
Published: September 2020

For the interpretation of archaeological geophysical data as archaeological features, it is essential that the recorded anomalies can be clearly delineated and analyzed, and therefore, care has been taken to obtain the best possible data. However, as with all measurements, data are degraded by unwanted components, or noise. This review clarifies the terminology, discusses the four major sources of noise (instrument, use of instrument, external, soil), and demonstrates how it can be characterized using geostatistical and wavenumber methods. It is important to recognize that even with improved instruments, some noise sources, like soil noise, may persist and that degraded data may be the result of unexpected sources, for example, global positioning system synchronization problems. Suggestions for the evaluation and recording of noise levels are provided to allow estimation of the limit of detection for archaeological geophysical anomalies.
Eco-Efficiency and Private Firms’ Relationships with Heterogeneous Public Stakeholders in China
Authors: Chen Jiawen , Liu Linlin
Published: September 2020

Private firms have been struggling to simultaneously achieve both environmental and economic goals. The concept of eco-efficiency captures the extent to which firms gain competitiveness through environmental management. Based on stakeholder salience theory and organizational learning theory, this study proposes that relationship with public stakeholders can hinder or promote private firms’ eco-efficiency. Our findings showed that firm eco-efficiency is reduced by a relationship with the government but is enhanced by relationships with non-governmental organizations (NGOs). This study also found that the effects on eco-efficiency of a firm’s relationship with public stakeholders are contingent on firm size. The findings of this study shed light on the organizational learning perspective of eco-efficiency and multi-stakeholder management by theoretically and empirically differentiating the effects on firm eco-efficiency of relationships with the government and NGOs.
Three-Dimensional Indoor Fire Evacuation Routing
Authors: Zhou Yan , Pang Yuling , Chen Fen , Zhang Yeting
Published: September 2020

Traditional indoor navigation algorithms generally only consider the geometrical information of indoor space. However, the environmental information and semantic parameters of a fire are also important for evacuation routing in the case of a fire. It is difficult for traditional indoor navigation algorithms to dynamically find an indoor path when a fire develops. To address this problem, we developed a multi-semantic constrained three-dimensional (3D) indoor fire evacuation routing method that considers multi-dimensional indoor fire scene-related semantics, such as path accessibility, path recognition degree, and fire parameters. Our method enhances the navigation semantics of indoor space by extending the fire-related components of indoor model based on IndoorGML and integrating location semantics of IndoorLocationGML. We also propose quantifiable indoor fire-oriented routing semantics and establish a navigation cost function that evaluates semantic changes during a fire. We designed an indoor routing algorithm with multiple semantic constraints based on the A* algorithm. The indoor routing results were analyzed and compared in simulation experiments. The experimental results showed that the proposed model can remove unusable nodes and edges from the obtained navigation path and provides a safer and more effective evacuation route than traditional algorithms.
Redox Regulation of STAT1 and STAT3 Signaling
Authors: Butturini Elena , Carcereri de Prati Alessandra , Mariotto Sofia
Published: September 2020

STAT1 and STAT3 are nuclear transcription factors that regulate genes involved in cell cycle, cell survival and immune response. The cross-talk between these signaling pathways determines how cells integrate the environmental signals received ultimately translating them in transcriptional regulation of specific sets of genes. Despite being activated downstream of common cytokine and growth factors, STAT1 and STAT3 play essentially antagonistic roles and the disruption of their balance directs cells from survival to apoptotic cell death or from inflammatory to anti-inflammatory responses. Different mechanisms are proposed to explain this yin-yang relationship. Considering the redox aspect of STATs proteins, this review attempts to summarize the current knowledge of redox regulation of STAT1 and STAT3 signaling focusing the attention on the post-translational modifications that affect their activity.
Novel Sub-Clustering of Class III Skeletal Malocclusion Phenotypes in a Southern European Population Based on Proportional Measurements
Authors: Frutos-Valle Leixuri de , Martín Conchita , Alarcón José Antonio , Palma-Fernández Juan Carlos , Ortega Ricardo , Iglesias-Linares Alejandro
Published: September 2020

Current phenotypic characterizations of Class III malocclusion are influenced more by gender or ethnic origin than by raw linear skeletal measurements. The aim of the present research is to develop a Class III skeletal malocclusion sub-phenotype characterization based on proportional cranial measurements using principal component analysis and cluster analysis. Radiometric data from 212 adult subjects (115 women and 96 men) of southern European origin affected by Class III skeletal malocclusion were analyzed. A total of 120 measurements were made, 26 were proportional skeletal measurements, which were used to perform principal component analysis and subsequent cluster analysis. The remaining 94 supplementary measurements were used for a greater description of the identified clusters. Principal component analysis established eight principal components that explained 85.1% of the total variance. The first three principal components explained 51.4% of the variance and described mandibular proportions, anterior facial height proportions, and posterior–anterior cranial proportions. Cluster analysis established four phenotypic subgroups, representing 18.4% (C1), 20.75% (C2), 38.68% (C3), and 22.17% (C4) of the sample. A new sub-clustering of skeletal Class III malocclusions that avoids gender influence is provided. Our results improve clinicians’ resources for Class III malocclusion and could improve the diagnostic and treatment approaches for this malocclusion.
Impact of Psychological Distress and Sleep Quality on Balance Confidence, Muscle Strength, and Functional Balance in Community-Dwelling Middle-Aged and Older People
Authors: Fábrega-Cuadros Raquel , Aibar-Almazán Agustín , Martínez-Amat Antonio , Hita-Contreras Fidel
Published: September 2020

The objective was to evaluate the associations of psychological distress and sleep quality with balance confidence, muscle strength, and functional balance among community-dwelling middle-aged and older people. An analytical cross-sectional study was conducted (n = 304). Balance confidence (Activities-specific Balance Confidence scale, ABC), muscle strength (hand grip dynamometer), and functional balance (Timed Up-and-Go test) were assessed. Psychological distress and sleep quality were evaluated by the Hospital Anxiety and Depression Scale and the Pittsburgh Sleep Quality Index, respectively. Age, sex, physical activity level, nutritional status, and fatigue were included as possible confounders. Multivariate linear and logistic regressions were performed. Higher values of anxiety (OR = 1.10), fatigue (OR = 1.04), and older age (OR = 1.08) were associated with an increased risk of falling (ABC < 67%). Greater muscle strength was associated with male sex and improved nutritional status (adjusted R2 = 0.39). On the other hand, being older and using sleeping medication were linked to poorer functional balance (adjusted R2 = 0.115). In conclusion, greater anxiety levels and the use of sleep medication were linked to a high risk of falling and poorer functional balance, respectively. No associations were found between muscle strength and sleep quality, anxiety, or depression.
Uninterrupted or Minimally Interrupted Direct Oral Anticoagulant Therapy is a Safe Alternative to Vitamin K Antagonists in Patients Undergoing Catheter Ablation for Atrial Fibrillation: An Updated Meta-Analysis
Authors: Ottóffy Máté , Mátrai Péter , Farkas Nelli , Hegyi Péter , Czopf László , Márta Katalin , Garami András , Balaskó Márta , Pótóné-Oláh Emőke , Mikó Alexandra , Rostás Ildikó , Wobbe Bastian , Habon Tamás
Published: September 2020

Adequate anticoagulation during catheter ablation (CA) for atrial fibrillation (AF) is crucial for the prevention of both thromboembolic events and life-threatening bleeding. The purpose of this updated meta-analysis is to compare the safety and efficacy of uninterrupted and minimally interrupted periprocedural direct oral anticoagulant (DOAC) protocols and uninterrupted vitamin K antagonist (VKA) therapy in patients undergoing CA for AF based on the latest evidence. Randomized controlled trials, prospective observational studies, and retrospective registries comparing DOACs to VKAs were identified in multiple databases (Embase, MEDLINE via PubMed, CENTRAL, and Scopus). The primary outcomes were stroke or transient ischemic attack (TIA), major bleeding, and net clinical benefit. Forty-two studies with a total of 22,715 patients were included in the final analysis. The occurrence of major bleeding was significantly lower in patients assigned to uninterrupted DOAC treatment compared to VKAs (pooled odds ratio (POR): 0.71, confidence interval (CI): 0.51–0.99). The pooled analysis of both uninterrupted and minimally interrupted DOAC groups also showed significant reduction in major bleeding events (POR: 0.70, CI: 0.53–0.93). The incidence of thromboembolic events was low, with no significant difference between groups. This updated meta-analysis showed that DOAC therapy is as effective as VKA in preventing stroke and TIA. Minimally interrupted DOAC therapy is a non-inferior periprocedural anticoagulation strategy; however, uninterrupted DOAC therapy showed superiority compared to VKA with regard to major, life-threatening bleeding. Based on our in-depth analysis, we conclude that both DOAC strategies are equally safe and preferable alternatives to VKAs in patients undergoing CA for AF.
Betaglycan Gene (TGFBR3) Polymorphism Is Associated with Increased Risk of Endometrial Cancer
Authors: Zakrzewski Piotr K. , Forma Ewa , Cygankiewicz Adam I. , Bryś Magdalena , Wójcik-Krowiranda Katarzyna , Bieńkiewicz Andrzej , Semczuk Andrzej , Krajewska Wanda M.
Published: September 2020

We investigated single nucleotide polymorphism (SNP) of the betaglycan gene (TGFBR3) encoding the TGFβ co-receptor in endometrial cancer (EC) and its association with betaglycan expression. The study group included 153 women diagnosed with EC and 248 cancer-free controls. SNP genotyping and gene expression were analyzed using TaqMan probes. Three out of the eight SNPs tested, i.e., rs12566180 (CT; OR = 2.22; 95% CI = 1.15–4.30; p = 0.0177), rs6680463 (GC; OR = 2.34; 95% CI = 1.20–4.53; p = 0.0120) and rs2296621 (TT; OR = 6.40; 95% CI = 1.18–34.84; p = 0.0317) were found to be significantly associated with increased risk of EC (adjusted to age, body mass index, menarche and parity). Among the analyzed SNPs, only rs2296621 demonstrated the impact on the increased cancer aggressiveness evaluated by the WHO grading system (G3 vs. G1/2, GT—OR = 4.04; 95% CI = 1.56–10.51; p = 0.0026; T—OR = 2.38; 95% CI = 1.16–4.85; p = 0.0151). Linkage disequilibrium (LD) analysis revealed high LD (r2 ≥ 0.8) in two haploblocks, constructed by rs2770186/rs12141128 and rs12566180/rs6680463, respectively. In the case of C/C haplotype (OR = 4.82; 95% CI = 1.54–15.07; p = 0.0116—Bonferroni corrected) and T/G haplotype (OR = 3.25; 95% CI = 1.29–8.15; p = 0.0328—Bonferroni corrected) in haploblock rs12566180/rs6680463, significantly higher frequency was observed in patients with EC as compared to the control group. The genotype-phenotype studies showed that SNPs of the TGFBR3 gene associated with an increased risk of EC, i.e., rs12566180 and rs2296621 may affect betaglycan expression at the transcriptomic level (rs12566180—CC vs. TT, p < 0.01; rs2296621—GG vs. TT, p < 0.001, GT vs. TT, p < 0.05). Functional consequences of evaluated TGFBR3 gene SNPs were supported by RegulomeDB search. In conclusion, polymorphism of the TGFBR3 gene may be associated with an increased EC occurrence, as well as may be the molecular mechanism responsible for observed betaglycan down-regulation in EC patients.
From Magneto-Dielectric Biocomposite Films to Microstrip Antenna Devices
Authors: de Menezes Fernando Lima , Andrade Neto Davino Machado , Rodrigues Maria do Livramento Linhares , Lima Helder Levi Silva , Paiva Denis Valony Martins , da Silva Marcelo Antônio Santos , Fechine Lillian Maria Uchôa Dutra , Sombra Antônio Sérgio Bezerra , Freire Rafael Melo , Denardin Juliano Casagrande , Rosa Morsyleide de Freitas , de Souza Filho Men de Sá Moreira , Mazzetto Selma Elaine , Fechine Pierre Basílio Almeida
Published: September 2020

Magneto-dielectric composites are interesting advanced materials principally due to their potential applications in electronic fields, such as in microstrip antennas substrates. In this work, we developed superparamagnetic polymer-based films using the biopolymeric matrices chitosan (Ch), cellulose (BC) and collagen (Col). For this proposal, we synthesized superparamagnetic iron oxide nanoparticles (SPIONs) functionalized with polyethyleneimine with a cheap method using sonochemistry. Further, the SPIONs were dispersed into polymer matrices and the composites were evaluated regarding morphology, thermal, dielectric and magnetic properties and their application as microstrip antennas substrates. Microscopically, all tested films presented a uniform dispersion profile, principally due to polyethyleneimine coating. Under an operating frequency (fo) of 4.45 GHz, Ch, BC and Col-based SPION substrates showed moderate dielectric constant (ε′) values in the range of 5.2–8.3, 6.7–8.4 and 5.9–9.1, respectively. Furthermore, the prepared films showed no hysteresis loop, thereby providing evidence of superparamagnetism. The microstrip antennas showed considerable bandwidths (3.37–6.34%) and a return loss lower than −10 dB. Besides, the fo were modulated according to the addition of SPIONs, varying in the range of 4.69–5.55, 4.63–5.18 and 4.93–5.44 GHz, for Ch, BC and Col-based substrates, respectively. Moreover, considering best modulation of ε′ and fo, the Ch-based SPION film showed the most suitable profile as a microstrip antenna substrate.
Effect of Structural Parameters on the Deformational Behaviors of Multiply 3D Layer-by-Layer Angle-Interlock Para-Aramid Fabric for Fiber-Reinforcement Composite
Authors: Abtew Mulat Alubel , Boussu Francois , Bruniaux Pascal , Loghin Carmen , Cristian Irina
Published: September 2020

Materials used in the technical application including composite reinforcements and ballistic fabrics should show not only good mechanical performance but also better deformational behaviors. Meanwhile, three dimensional (3D) warp interlock fabrics have been widely employed in such applications to substitute the two dimensional (2D) fabrics because of their enhanced through-the-thickness performance and excellent formability. The deformational behaviors of such 3D warp interlock fabrics have been also influenced by various internal and external parameters. To understand and fill this gap, the current paper investigates the effects of the warp yarn interchange ratios inside the fabric structure on the formability behaviors of dry 3D warp interlock p-aramid fabrics. Four 3D warp interlock architecture types made with different binding and stuffer warp yarn interchange ratios were designed and manufactured. An adapted hydraulic-driven stamping bench along with hemispherical punch was utilized for better forming behavior analysis such as in-plane shear angle and its recovery, material drawing-in and its recovery, deformational depth recovery, and required stamping forces. Based on the investigation of various formability behaviors, the formability of (3D) warp interlock fabrics were greatly influenced by the binding and stuffer warp yarns interchange ratio inside the 3D warp interlock structure. For example, preform 3D-8W-0S exhibited a maximum deformational height recovery percentage of 5.1%, whereas 3D-4W-8S recorded only 0.72%. Preform 3D-8W-4S and 3D-8W-8S revealed 1.45% and 4.35% recovery percentages toward the deformational height at maximum position. Besides, sample 3D-4S-8W revealed the maximum drawing-in recovery percentage of 43.13% and 46.98% in the machine and cross direction, respectively, around the preform peripheral edges. On the contrary, samples with higher binding warp yarns as 3D-8W-0S show the maximum drawing-in recovery percentages values of 31.21% and 34.99% in the machine and cross directions respectively.
Evidence of Stable Foraminifera Biomineralization during the Last Two Climate Cycles in the Tropical Atlantic Ocean
Authors: Zarkogiannis Stergios D. , Antonarakou Assimina , Fernandez Vincent , Mortyn P. Graham , Kontakiotis George , Drinia Hara , Greaves Mervyn
Published: September 2020

Planktonic foraminiferal biomineralization intensity, reflected by the weight of their shell calcite mass, affects global carbonate deposition and is known to follow climatic cycles by being increased during glacial stages and decreased during interglacial stages. Here, we measure the dissolution state and the mass of the shells of the planktonic foraminifera species Globigerina bulloides from a Tropical Eastern North Atlantic site over the last two glacial–interglacial climatic transitions, and we report no major changes in plankton calcite production with the atmospheric pCO2 variations. We attribute this consistency in foraminifera calcification to the climatic and hydrological stability of the tropical regions. However, we recorded increased shell masses midway through the penultimate deglaciation (Termination II). In order to elucidate the cause of the increased shell weights, we performed δ18O, Mg/Ca, and μCT measurements on the same shells from a number of samples surrounding this event. Compared with the lighter ones, we find that the foraminifera of increased weight are internally contaminated by sediment infilling and that their shell masses respond to local surface seawater density changes.
Knowledge Translation Supports Community Conservation Efforts to Protect and Restore a Local Marine Environment: A Case Study of Átl’ḵa7tsem/Txwnéwu7ts/Howe Sound, British Columbia, Canada
Authors: Chapman Jennifer , Dearden Amber , Miller Aroha
Published: September 2020

Individuals, communities, organizations, and governments are the building blocks of economies. All require awareness, information, and achievable actions to contribute to moving towards healthy oceans, the base of a robust blue economy. Ocean Watch, a program run by Ocean Wise Conservation Association, was created to translate scientific understanding, combined with community and traditional knowledge, to empower local action for improved marine health. Clear improvements have been made in the Átl’ḵa7tsem/Txwnéwu7ts/Howe Sound marine environment, which have been captured in an updated report following from the original 2017 publication. Information within the reports illustrates the connection of communities and the marine environment through articles describing seven themes, which are: (1) Species and Habitat; (2) Clean Water; (3) Sense of Place; (4) Coastal Development and Livelihoods; (5) Stewardship and Governance; (6) Oceanography and Climate Change; and (7) Seafood. Articles such as the 2017 article: “Sea Stars: wasting disease taking its toll” gave background, rationale for importance, current status, current actions, and recommended actions to improve the health status (healthy, caution, critical, limited/no data). The health status for 10 of 28 reassessed articles improved largely due to actions taken by local communities, as recommended in the 2017 report. However, more work is needed, especially for areas of marine health that were not improving and to address threats from climate change. Establishing a sustainable socio-ecological relationship with the ocean is necessary if we are to protect and restore the health of all components of the ecosystem. Empowering communities to take action improves ocean health, which is inherently linked to the health of individuals, communities, and economies.
Impact of Value Co-Creation on International Customer Satisfaction in the Airsoft Industry: Does Country of Origin Matter?
Authors: Menet Gabriela , Szarucki Marek
Published: September 2020

The paper’s objective is to investigate the impact of value proposition co-creation on international customer satisfaction in the airsoft industry. This empirical paper aims at answering a question “Which factors influence satisfaction of the international customers involved in the process of value co-creation in the airsoft industry” and sets a hypothesis that value co-creators’ country of origin has a positive impact on customers’ satisfaction. A case study approach of an entrepreneurial company (GATE) was supplemented with data collected via a survey (n = 176), where consumers’ perception of the firm’s value proposition and its influence on their satisfaction were investigated. The study contributes to the value creation theory by identifying the main factors influencing customer satisfaction in the airsoft industry and verifying whether the co-creators’ origin affects the factors’ ratings. The results indicate that the most crucial factors influencing international customer satisfaction in this industry are quality level and product functionality and that the country of origin of customers has no significant impact on international customer satisfaction.
Segmental Pulmonary Hypertension in Children with Congenital Heart Disease
Authors: Das Bibhuti B. , Frank Benjamin , Ivy Dunbar
Published: September 2020

Segmental pulmonary hypertension is a complex condition in children that encompasses many congenital heart diseases including pulmonary atresia with ventricular septal defect, hemitruncus/truncus arteriosus with branch pulmonary artery stenosis, unilateral absent pulmonary artery, and several post-tricuspid shunt lesions. Multimodality imaging is required to confirm and assess pulmonary vascular disease in subjects with major aorto-pulmonary collaterals. We describe 3 children with complex congenital heart defects who have a variable degree of segmental pulmonary hypertension and discuss management strategies and the role of interventional and/or pulmonary hypertension targeted therapies.
Cesarean Scar Pregnancy Successfully Managed to Term: When the Patient Is Determined to Keep the Pregnancy
Authors: Kutlesic Ranko , Kutlesic Marija , Vukomanovic Predrag , Stefanovic Milan , Mostic-Stanisic Danka
Published: September 2020

Cesarean scar pregnancy (CSP) is a rare form of ectopic pregnancy, defined as the implantation of the gestational sac at the uterine incision scar of the previous cesarean section. This condition is associated with severe maternal and fetal/neonatal complications, including severe bleeding, rupture of the uterus, fetal demise, or preterm delivery. In view of these, early diagnosis allows the option of termination of pregnancy. In this case report, we present a patient with a cesarean scar pregnancy who was diagnosed at the sixth week of gestation but declined early termination of the pregnancy and was managed to the 38th week. Placenta previa was confirmed in the second trimester. A planned cesarean section was performed that resulted in the birth of a live full-term neonate. Intraoperatively, placenta percreta was diagnosed, and due to uncontrollable bleeding, a hysterectomy was performed. The postoperative course was uneventful. In cases where an early diagnosis of CSP is made, women should be counseled that this will almost certainly evolve to placenta previa, and the associated risks should be explained. Close follow-up of CSP is mandatory if expectant management is selected. Further studies are needed for definitive conclusions and to determine the risks of expectant management.
Obesity and Brain Function: The Brain–Body Crosstalk
Authors: Sui Sophia X. , Pasco Julie A.
Published: September 2020

Dementia comprises a wide range of progressive and acquired neurocognitive disorders. Obesity, defined as excessive body fat tissue, is a common health issue world-wide and a risk factor for dementia. The adverse effects of obesity on the brain and the central nervous system have been the subject of considerable research. The aim of this review is to explore the available evidence in the field of body–brain crosstalk focusing on obesity and brain function, to identify the major research measurements and methodologies used in the field, to discuss the potential risk factors and biological mechanisms, and to identify the research gap as a precursor to systematic reviews and empirical studies in more focused topics related to the obesity–brain relationship. To conclude, obesity appears to be associated with reduced brain function. However, obesity is a complex health condition, while the human brain is the most complicated organ, so research in this area is difficult. Inconsistency in definitions and measurement techniques detract from the literature on brain–body relationships. Advanced techniques developed in recent years are capable of improving investigations of this relationship.
Tailoring Charged Nanofiltration Membrane Based on Non-Aromatic Tris(3-aminopropyl)amine for Effective Water Softening
Authors: Jin Pengrui , Robeyn Michiel , Zheng Junfeng , Yuan Shushan , Van der Bruggen Bart
Published: September 2020

High-performance positively-charged nanofiltration (NF) membranes have a profound significance for water softening. In this work, a novel monomer, tris(3-aminopropyl)amine (TAEA), with one tertiary amine group and three primary amine groups, was blended with trace amounts of piperazine (PIP) in aqueous solution to fabricate a positively-charged NF membrane with tunable performance. As the molecular structures of TAEA and PIP are totally different, the chemical composition and structure of the polyamine selective layer could be tailored via varying the PIP content. The resulting optimal membrane exhibited an excellent water permeability of 10.2 LMH bar−1 and a high rejection of MgCl2 (92.4%), due to the incorporation of TAEA/PIP. In addition, this TAEA NF membrane has a superior long-term stability. Thus, this work provides a facile way to prepare a positively charged membrane with an efficient water softening ability.
SARS-CoV-2: From Structure to Pathology, Host Immune Response and Therapeutic Management
Authors: Mihaescu Grigore , Chifiriuc Mariana Carmen , Iliescu Ciprian , Vrancianu Corneliu Ovidiu , Ditu Lia-Mara , Marutescu Luminita Gabriela , Grigore Raluca , Berteșteanu Șerban , Constantin Marian , Gradisteanu Pircalabioru Gratiela
Published: September 2020

Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the COVID-19 pandemic, has 80% sequence homology with SARS-CoV-1 and 96–98% homology with coronaviruses isolated from bats. The spread of infection is favored by prolonged exposure to high densities of aerosols indoors. Current studies have shown that SARS-CoV-2 is much more stable than other coronaviruses and viral respiratory pathogens. The severe forms of infection are associated with several risk factors, including advanced age, metabolic syndrome, diabetes, obesity, chronic inflammatory or autoimmune disease, and other preexisting infectious diseases, all having in common the pre-existence of a pro-inflammatory condition. Consequently, it is essential to understand the relationship between the inflammatory process and the specific immune response in SARS-CoV-2 infection. In this review, we present a general characterization of the SARS-CoV-2 virus (origin, sensitivity to chemical and physical factors, multiplication cycle, genetic variability), the molecular mechanisms of COVID-19 pathology, the host immune response and discuss how the inflammatory conditions associated with different diseases could increase the risk of COVID-19. Last, but not least, we briefly review the SARS-CoV-2 diagnostics, pharmacology, and future approaches toward vaccine development.
Geophysical Prospecting for Groundwater Resources in Phosphate Deposits (Morocco)
Authors: Ihbach Fatim-Zahra , Kchikach Azzouz , Jaffal Mohammed , El Azzab Driss , Khadiri Yazami Oussama , Jourani Es-Said , Peña Ruano José Antonio , Olaiz Oier Ardanaz , Dávila Luis Vizcaíno
Published: September 2020

The Moroccan phosphate deposits are the largest in the world. Phosphatic layers are extracted in open-pit mines mainly in the sedimentary basins of Gantour and Ouled Abdoun in Central Morocco. The purpose of this study was to prospect and evaluate the water potential of aquifers incorporated in the phosphatic series using the following geophysical methods: Magnetic resonance sounding (MRS), electrical resistivity tomography (ERT), time-domain electromagnetics (TDEM), and frequency-domain electromagnetics (FDEM). The objective was, on the one hand, to contribute to the success of the drinking water supply program in rural areas around mining sites, and on the other hand, to delimit flooded layers in the phosphatic series to predict the necessary mining design for their extraction. The use of geophysical methods made it possible to stratigraphically locate the most important aquifers of the phosphatic series. Their hydraulic parameters can be evaluated using the MRS method while the mapping of their recharge areas is possible through FDEM surveys. The results obtained in two selected experimental zones in the mining sites of Youssoufia and Khouribga are discussed in this paper. The application of the implemented approach to large phosphate mines is in progress in partnership with the mining industry.
Agricultural and Biomedical Applications of Chitosan-Based Nanomaterials
Authors: Bandara Subhani , Du Hongbo , Carson Laura , Bradford Debra , Kommalapati Raghava
Published: September 2020

Chitosan has emerged as a biodegradable, nontoxic polymer with multiple beneficial applications in the agricultural and biomedical sectors. As nanotechnology has evolved as a promising field, researchers have incorporated chitosan-based nanomaterials in a variety of products to enhance their efficacy and biocompatibility. Moreover, due to its inherent antimicrobial and chelating properties, and the availability of modifiable functional groups, chitosan nanoparticles were also directly used in a variety of applications. In this review, the use of chitosan-based nanomaterials in agricultural and biomedical fields related to the management of abiotic stress in plants, water availability for crops, controlling foodborne pathogens, and cancer photothermal therapy is discussed, with some insights into the possible mechanisms of action. Additionally, the toxicity arising from the accumulation of these nanomaterials in biological systems and future research avenues that had gained limited attention from the scientific community are discussed here. Overall, chitosan-based nanomaterials show promising characteristics for sustainable agricultural practices and effective healthcare in an eco-friendly manner.
More Than One Reason for Oral, a New Journal
Authors: Campisi Giuseppina
Published: September 2020

Beyond my obvious enthusiasm due to the nascent state that generally makes us see everything with optimism, as Editor in Chief of this new publishing experience, I start by asking myself a question: is another dental journal called Oral really necessary [...]
Enhanced Adsorptive Removal of β-Estradiol from Aqueous and Wastewater Samples by Magnetic Nano-Akaganeite: Adsorption Isotherms, Kinetics, and Mechanism
Authors: Mpupa Anele , Nqombolo Azile , Mizaikoff Boris , Nomngongo Philiswa Nosizo
Published: September 2020

A surfactant-free method was used to synthesize iron oxyhydroxide (akaganeite, β-FeOOH) nanorods and characterized using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy combined with energy-dispersive X-ray spectroscopy (SEM-EDS), and transmission electron microscopy (TEM). The synthesized nanoadsorbent was applied for the adsorptive removal of β-estradiol from aqueous solutions. The parameters affecting the adsorption were optimized using a multivariate approach based on the Box–Behnken design with the desirability function. Under the optimum conditions, the equilibrium data were investigated using two and three parameter isotherms, such as the Langmuir, Freundlich, Dubinin–Radushkevich, Redlich–Peterson, and Sips models. The adsorption data were described as Langmuir and Sips isotherm models and the maximum adsorption capacities in Langmuir and Sips of the β-FeOOH nanorods were 97.0 and 103 mg g−1, respectively. The adjusted non-linear adsorption capacities were 102 and 104 mg g−1 for Langmuir and Sips, respectively. The kinetics data were analyzed by five different kinetic models, such as the pseudo-first order, pseudo-second order, intraparticle, as well as Boyd and Elovich models. The method was applied for the removal β-estradiol in spiked recoveries of wastewater, river, and tap water samples, and the removal efficiency ranged from 93–100%. The adsorbent could be reused up to six times after regeneration with acetonitrile without an obvious loss in the removal efficiency (%RE = 95.4 ± 1.9%). Based on the results obtained, it was concluded that the β-FeOOH nanorods proved to be suitable for the efficient removal of β-estradiol from environmental matrices.
Connecting Risk and Resilience for a Power System Using the Portland Hills Fault Case Study
Authors: Chalishazar Vishvas H. , Brekken Ted K. A. , Johnson Darin , Yu Kent , Newell James , Chin King , Weik Rob , Dierickx Emilie , Craven Matthew , Sauter Maty , Olennikov Andrey , Galaway Jennifer , Radil Ann
Published: September 2020

Active seismic faults in the Pacific Northwest area have encouraged electric utilities in the region to deeply contemplate and proactively intervene to support grid resilience. To further this effort this research introduces Monte Carlo (MC)-based power system modeling as a means to inform the Performance Based Earthquake Engineering method and simulates 100,000 sample earthquakes of a 6.8 magnitude (M6.8) Portland Hills Fault (PHF) scenario in the Portland General Electric (PGE) service territory as a proof of concept. This paper also proposes the resilience metric Seismic Load Recovery Factor (SLRF) to quantify the recovery of a downed power system and thus can be used to quantify earthquake economic risk. Using MC results, the SLRF was evaluated to be 19.7 h and the expected economic consequence cost of a M6.8 PHF event was found to be $180 million with an annualized risk of $90,000 given the event’s 1 in 2000 year probability of occurrence. The MC results also identified the eight most consequential substations in the PGE system—i.e., those that contributed to maximum load loss. This paper concludes that retrofitting these substations reduced the expected consequence cost of a M6.8 PHF event to $117 million.
A Confidence Interval-Based Process Optimization Method Using Second-Order Polynomial Regression Analysis
Authors: Yu Jungwon , Yang Soyoung , Kim Jinhong , Lee Youngjae , Lim Kil-Taek , Kim Seiki , Ryu Sung-Soo , Jeong Hyeondeok
Published: September 2020

In the manufacturing processes, process optimization tasks, to optimize their product quality, can be performed through the following procedures. First, process models mimicking functional relationships between quality characteristics and controllable factors are constructed. Next, based on these models, objective functions formulating process optimization problems are defined. Finally, optimization algorithms are applied for finding solutions for these functions. It is important to note that different solutions can be found whenever these algorithms are independently executed if a unique solution does not exist; this may cause confusion for process operators and engineers. This paper proposes a confidence interval (CI)-based process optimization method using second-order polynomial regression analysis. This method evaluates the quality of the different solutions in terms of the lengths of their CIs; these CIs enclose the outputs of the regression models for these solutions. As the CIs become narrower, the uncertainty about the solutions decreases (i.e., they become statistically significant). In the proposed method, after sorting the different solutions in ascending order, according to the lengths, the first few solutions are selected and recommended for the users. To verify the performance, the method is applied to a process dataset, gathered from a ball mill, used to grind ceramic powders and mix these powders with solvents and some additives. Simulation results show that this method can provide good solutions from a statistical perspective; among the provided solutions, the users are able to flexibly choose and use proper solutions fulfilling key requirements for target processes.
Sustainable Land-Use Pathway Ranking and Selection
Authors: Holloway Garth John
Published: September 2020

The desire for refining status quo cost–benefit protocols to fully encompass econometric model uncertainty motivates the search for improved technology. Availability of unique Ethiopian highlands milk-market livestock data provides an ideal laboratory for investigation of alternative land-use pathway designs. In these contexts, we present novel methodology for ranking and selecting sustainable ‘land-use pathways,’ arguing that the methodology is central to sustainable-land-use-policy prescriptions, providing essential innovation to assessments hitherto devoid of probabilistic foundation. Demonstrating routine implementation of Markov-Chain, Monte-Carlo procedure, ranking-and-selection enactment is widely disseminable and potentially valuable to land-use policy prescription. Application to a sample of Ethiopian-highlands, land-dependent households highlights empirical gains compared to conventional methodology. Applications and extensions that profit future land-use sustainability within the Ethiopian highlands and, also, more generally, are discussed.
Automatic Repair of Semantic Defects Using Restraint Mechanisms
Authors: Dong Yukun , Zhang Li , Pang Shanchen , Yin Wenjing , Wu Mengying , Wu Meng , Li Haojie
Published: September 2020

Recently, software, especially CPS and Internet of Things (IoT), increasingly have high requirements for quality, while program defects exist inevitably duo to the high complexity. Program defect repair faces serious challenges in that such repairs require considerable manpower, and the existing automatic repair approaches have difficulty generating correct patches efficiently. This paper proposes an automatic method for repairing semantic defects in Java programs based on restricted sets which refer to the interval domains of related variables that can trigger program semantic defects. Our work introduces a repair mechanism symmetrically combining defect patterns and repair templates. First, the program semantic defects are summarized into defect patterns according to their grammar and semantic features. A repair template for each type of defect pattern is predefined based on a restricted-set. Then, for each specific defect, a patch statement is automatically synthesized according to the repair template, and the detected defect information is reported by the static detection tool (DTSJava). Next, the patch location is determined by the def-use chain of defect-related variables. Finally, we evaluate the patches generated by our method using DTSJava. We implemented the method in the defect automatic repair prototype tool DTSFix to verify the effect of repairing the semantic defects detected by DTSJava in 6 Java open-source projects. The experimental results showed that 109 of 129 program semantic defects were repaired.
Wavelet Feature Outdoor Fingerprint Localization Based on ResNet and Deep Convolution GAN
Authors: Lei Yingke , Li Da , Zhang Haichuan , Li Xin
Published: September 2020

Due to the explosive development of location-based services (LBS), localization has attracted significant research attention over the past decade. Among the associated techniques, wireless fingerprint positioning has garnered much interest due to its compatibility with existing hardware. At present, with the widespread deployment of long-term evolution (LTE) networks and the uniqueness of wireless information fingerprints, fingerprint positioning based on LTE networks is the mainstream method for outdoor positioning. However, in order to improve its accuracy, this method needs to collect enough data at a large number of reference points, which is a labor-intensive task. In this paper, experimental data are collected at different reference points and then converted into wavelet feature maps. Then, a Deep Convolutional Generative Adversarial Network (DCGAN) is leveraged to generate a symmetric fingerprint database. Localization is then carried out by the proposed Deep Residual Network (Resnet), which is capable of learning reliable features from a fingerprint image database. To further increase the robustness of the positioning system, a variety of data enhancement methods are used. Finally, we experimentally demonstrate that the generated symmetric fingerprint database and proposed Resnet reduce the manpower required for fingerprint database collection and improve the accuracy of the outdoor positioning system.
Spectra of a Rydberg Atom in Crossed Electric and Magnetic Fields
Authors: Letunov Andrei , Lisitsa Valery
Published: September 2020

Contemporary spectroscopic studies of astrophysical and laboratory plasmas frequently deal with extremely large values of principle quantum numbers of atomic systems. These atomic states are very sensitive to electric and magnetic fields of the surrounding medium. While interpreting the spectra of such excited atomic systems, one faces the problem of a huge array of radiative transitions between highly excited atomic levels. Moreover, external electric and magnetic fields significantly complicate the problem because of the absence of standard selection rules typical for the spherical quantization. The analytical expression in the parabolic representation for dipole matrix elements obtained by Gordon contains hyper-geometric series and it has a very complex structure. The matrix elements that involve the presence of electric and magnetic fields are calculated while using a representation closely related to the parabolic quantization on two different axes. This matrix element depends in a complex way on the transition probabilities in the parabolic coordinate system (Gordon’s formulas) and the Wigner d-functions. This circumstance leads to even greater computational difficulties. A method of simplification of these complicated expressions for transition probabilities is demonstrated. The semiclassical approximation for coordinate matrix elements (Gulayev) and recurrence properties of the Wigner d-functions are used. The Hnβ line is under consideration. Specific calculations for the transition 10–8 in the case of parallel and perpendicular fields are presented.
Dark Entrepreneurship, the ‘Dark Triad’ and Its Potential ‘Light Triad’ Realization in ‘Green Entrepreneurship’
Authors: Cooke Philip
Published: September 2020

This contribution seeks to achieve three main objectives. First it draws on a substantial, but often overlooked literature on wide-scale international decline in entrepreneurship as recorded in the ‘business dynamics’ literature. This has serious implications for academic study of entrepreneurship which must re-direct its focus to problems of entrepreneurial unattractiveness dating from at least the 1980s. More important, public policy makers and political ideologists need further to be apprised of the erroneous nature of many of their beliefs and further change the subsidy regimes they bestow on often unproductive entrepreneurship. Second, the contribution seeks one part of the explanation of the declining attractiveness of entrepreneurship in the psychology of the ‘dark triad’ of negative personality traits that has been connected to the literature on ‘dark entrepreneurship’ as a possible and partial, but important reason for the growing unattractiveness of entrepreneurship. The contribution devotes attention to the ‘Mindfulness’ movement in considering the detoxification of ‘dark entrepreneurship’. Finally, in what may be an original response to this analysis, the contribution draws attention to recent work on a putative ‘light triad’ of personality traits and applies it, possibly for the first time, to secondarily researched accounts of ‘green entrepreneurship’. The conclusion is that there may be a future for green entrepreneurship as a means for recovery in the current status of more traditional ‘business dynamics’.