bluuebunny/crossref_metadata_2025 huggingface dataset:
A juvenile locomotor program promotes vocal learning in zebra finches
Authors: Liu Wan-chun , Landstrom Michelle , Cealie MaKenna , MacKillop Iona
Published: June 2022

The evolution and development of complex, learned motor skills are thought to be closely associated with other locomotor movement and cognitive functions. However, it remains largely unknown how different neuromuscular programs may interconnect during the protracted developmental process. Here we use a songbird to examine the behavioral and neural substrates between the development of locomotor movement and vocal-motor learning. Juvenile songbirds escalate their locomotor activity during the sensitive period for vocal learning, followed by a surge of vocal practice. Individual variability of locomotor production is positively correlated with precision of tutor imitation and duration of multi-syllable sequences. Manipulation of juvenile locomotion significantly impacts the precision of vocal imitation and neural plasticity. The locomotor program developed during the sensitive period of vocal learning may enrich the neural substrates that promote the subsequent development of vocal learning.
Extending the time of coherent optical response in ensemble of singly-charged InGaAs quantum dots
Authors: Kosarev Alexander N. , Trifonov Artur V. , Yugova Irina A. , Yanibekov Iskander I. , Poltavtsev Sergey V. , Kamenskii Alexander N. , Scholz Sven E. , Sgroi Carlo Alberto , Ludwig Arne , Wieck Andreas D. , Yakovlev Dmitri R. , Bayer Manfred , Akimov Ilya A.
Published: June 2022

The ability to extend the time scale of the coherent optical response from large ensembles of quantum emitters is highly appealing for applications in quantum information devices. In semiconductor nanostructures, spin degrees of freedom can be used as auxiliary, powerful tools to modify the coherent optical dynamics. Here, we apply this approach to negatively charged (In,Ga)As/GaAs self-assembled quantum dots which are considered as excellent quantum emitters with robust optical coherence and high bandwidth. We study three-pulse spin-dependent photon echoes subject to moderate transverse magnetic fields up to 1 T. We demonstrate that the timescale of coherent optical response can be extended by at least an order of magnitude by the field. Without magnetic field, the photon echo decays with T2 = 0.45 ns which is determined by the radiative lifetime of trions T1 = 0.26 ns. In the presence of the transverse magnetic field, the decay of the photon echo signal is given by spin dephasing time of the ensemble of resident electrons T2,e ∼ 4 ns. We demonstrate that the non-zero transverse g-factor of the heavy holes in the trion state plays a crucial role in the temporal evolution and magnetic field dependence of the long-lived photon echo signal.
A computational study of the HO2+ SO3→ HOSO2+3O2reaction catalyzed by a water monomer, a water dimer and small clusters of sulfuric acid: kinetics and atmospheric implications
Authors: Zhang Yongqi , Cheng Yang , Zhang Tianlei , Wang Rui , Ji Jianwei , Xia Yu , Lily Makroni , Wang Zhuqing , Muthiah Balaganesh
Published: June 2022

The reaction mechanisms and kinetics for the HO2+ SO3→ HOSO2+3O2reaction catalyzed by a water monomer, a water dimer and small clusters of sulfuric acid have been studied theoretically by quantum chemical methods and the Master Equation/Rice–Ramsperger–Kassel–Marcus rate calculations.
A fluorescence digital image-based method using carbon quantum dots to evaluate the compliance of a biocidal agent
Authors: de Almeida João Paulo Barbosa , dos Santos Vagner Bezerra , do Nascimento Gustavo Alves , Suarez Willian Toito , de Azevedo Walter Mendes , Ferreira Aldebarã Fausto , Maia Matheus Valentin
Published: June 2022

A simple, low-cost and easy-to-handle procedure based on carbon quantum dots is proposed to check commercially available formulated microbicides that are used to mitigate the transmission of viruses, such as SARS-COV-2, or bacterial diseases.
Preparation of an electrochemical immunosensor based on a Cu/Cu2O-rGO@Au signal synergistic amplification strategy and efficient and sensitive detection of alpha-fetoprotein
Authors: Wang Min , Jiang Mingzhe , Liao Xiaochen , Wang Xiao , Lai Wenjing , Li Pengli , Li Jiajia , Hong Chenglin , Qi Yu
Published: June 2022

Cu/Cu2O combines the catalytic activity of metal oxides and the conductivity of metals to promote the amplification of electrical signals. rGO can anchor more Ab2 and Au NPs, enhance conductivity and biocompatibility, and enhance electrical signals.
CLiB – a novel cardiolipin-binder isolated via data-driven and in vitro screening
Authors: Kleinwächter Isabel , Mohr Bernadette , Joppe Aljoscha , Hellmann Nadja , Bereau Tristan , Osiewacz Heinz D. , Schneider Dirk
Published: June 2022

CLiB, a cardiolipin-binding molecules, affects respiration of cardiolipin-containing bacteria as well as of mitochondria.
Unequal sensitivities of energy levels in a high-symmetry Ho3+ complex towards lattice distortions
Authors: Bonde Niels A. , Appel Markus , Ollivier Jacques , Weihe Høgni , Bendix Jesper
Published: June 2022

Crystal field and hyperfine inhomogeneities from high-resolution inelastic neutron scattering spectroscopy.
Recent progress of the single crystal growth of homologous (InGaO3)m(ZnO)n
Authors: Kase Naoki , Kimizuka Noboru , Miyakawa Nobuaki
Published: June 2022

Crystal structure of the homologues series of (InGaZnO3)m(ZnO)n.
Prediction of the Be2B2monolayer: an ultrahigh capacity anode material for Li-ion and Na-ion batteries
Authors: Wu Yao , Hou Jianhua
Published: June 2022

We firstly propose a brand new kind of Be2B2monolayer, which exhibits excellent electrochemical properties. In particular, the ultra-low diffusion barrier and extremely high theoretical capacity well meet the requirements in Li/Na-ion batteries.
Spectroscopic evidence of S∴N and S∴O hemibonds in heterodimer cations
Authors: Sun Xiaonan , Xie Min , Qiu Wei , Wei Chengcheng , Chen Xujian , Hu Yongjun
Published: June 2022

The first spectral evidence for the formation of stable hemibonds between second-period elements (nitrogen or oxygen) and third-period elements (sulfur) in gas phase.
Magnetic orientation behavior of L-type zeolite with rare-earth elements under low magnetic field
Authors: Tabata Tomomi , Nagai Anna , Matsuda Motohide
Published: June 2022

A finding that L-type zeolite ion-exchanged with magnetic rare-earth elements can be oriented in a 0.9 T magnetic field is presented.
Pseudo 2-dimensional nanostructures of metal oxides for high-performance supercapacitors
Authors: Mandal Debabrata , Biswas Sudipta , Chowdhury Ananya , Chandra Amreesh
Published: June 2022

Hollow particles can be modelled as pseudo-2 dimensional nanostructures. The electrochemical performance of such novel structures supersedes that of their solid counterparts by many folds.
Recent advances in small molecular design for high performance non-fullerene organic solar cells
Authors: Gu Chuantao , Wang Xunchang , Wang Haicheng , Tian Yong , Ma Jiping , Yang Renqiang
Published: June 2022

This review summarized the recent advances in innovation of small molecule non-fullerene electron acceptors and structure–property relationships and compatibility of donors and acceptors.
Promoting effects of Y doping and FeOOH loading for efficient photoelectrochemical activity on BiVO4 electrodes
Authors: Guo Yuwei , Han Wei , Zhao Kaichen , Hao Shaojun , Shi Shenggang , Ding Yongping
Published: June 2022

An FeOOH/Y-BiVO4 photoelectrode with high PEC performance was obtained using a combination of Y-doping and modification with FeOOH. The FeOOH/Y-BiVO4 photoelectrode exhibited efficient PEC activity for solar water oxidation and wastewater treatment.
Amino-based covalent organic frameworks for a wide range of functional modification
Authors: Zhao Yuling , Xu Xianhui , Xu Chang , Meng Deyuan , Liang Xiaoqian , Qiu Jikuan
Published: June 2022

A versatile protocol for modification of amino-based COFs with desired functionalities was developedviatransforming the unreachable amino groups into imine, thiourea, amide and azo-based functional groups.
In situfabrication of HDA-mediated NiFe–Fe2O3nanorods: an efficient and recyclable heterogeneous catalyst for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in water
Authors: Agarwal Soniya , Dutta Apurba , Sarma Diganta , Deori Kalyanjyoti
Published: June 2022

A simple, facile and an effective route for the synthesis of 2,3-dihydroquinazolin-4(1H)-onesviamulti-component reactions using newly developed NiFe–Fe2O3nanorods as heterogeneous catalysts.
Bi2S3-decorated three-dimensional BiOCl as a Z-scheme heterojunction with highly exposed {001} facets of BiOCl for enhanced visible-light photocatalytic performance
Authors: Sun Mingming , Gao Ruixiao , Wang Bowei , Li Jiayi , Zhang Zijing , Bai Guoyi , Yan Xilong , Li Yang , Chen Ligong
Published: June 2022

In BOC-BS-x, the highly exposed {001} facets of BiOCl have more oxygen vacancies, which can facilitate the migration of carriers.
Synthesis and crystal structures of unsymmetrical wave-shaped heptathienoacenes
Authors: Wu Zhiping , Xu Wan , Li Chunli , Ma Zhiying , Wang Guangxia , Wang Hua
Published: June 2022

Three unsymmetric wave-shaped heptathienoacene UHT-1, UHT-2 and UHT-3 were synthesized by bb-DTT, bt-DTT, bs-DTT as building blocks via Negishi cross coupling and intramolecular cyclization reactions.
The effect of heteroatom doping on the active metal site of CoS2 for hydrogen evolution reaction
Authors: Shi Jianjian , Chen Tao , Sun Xiaoli
Published: June 2022

The linear relationship between ΔGH* and d-band centers of H adsorption sites.
Phase change composites of octadecane and gallium with expanded graphite as a carrier
Authors: Yao Yuchen , Cui Yuntao , Deng Zhongshan
Published: June 2022

The thermophysical properties of the novel phase change composites formed by simultaneously packing octadecane and gallium with expanded graphite as carrier can be adjusted in a wide range, creating more options for related fields.
A study of the synergetic effect between graphene oxide and transition metal oxides for energy storage
Authors: Lu Munan , Li Hao , Li Shijingmin , Yang Fucai , Cao Yi , Qiu Wenfeng
Published: June 2022

A series of graphene/transition metal oxide (TMO) composite films were prepared through an electrostatic self-assembly method.
Fundamental luminescence properties of Mn4+ activated Ca14Al10Zn6O35 phosphor
Authors: Lv Ting , Huang Jiquan , Yang Changliang , Wang Yun , Huang Qiufeng , Chen Jian , Guo Wang
Published: June 2022

A comprehensive study on the fundamental luminescence properties of Ca14Al10Zn6O35:Mn4+, which is universal for Mn4+-activated phosphors.
GaiaData Release 3
Authors: Montegriffo P. , De Angeli F. , Andrae R. , Riello M. , Pancino E. , Sanna N. , Bellazzini M. , Evans D. W. , Carrasco J. M. , Sordo R. , Busso G. , Cacciari C. , Jordi C. , van Leeuwen F. , Vallenari A. , Altavilla G. , Barstow M. A. , Brown A. G. A. , Burgess P. W. , Castellani M. , Cowell S. , Davidson M. , De Luise F. , Delchambre L. , Diener C. , Fabricius C. , Frémat Y. , Fouesneau M. , Gilmore G. , Giuffrida G. , Hambly N. C. , Harrison D. L. , Hidalgo S. , Hodgkin S. T. , Holland G. , Marinoni S. , Osborne P. J. , Pagani C. , Palaversa L. , Piersimoni A. M. , Pulone L. , Ragaini S. , Rainer M. , Richards P. J. , Rowell N. , Ruz-Mieres D. , Sarro L. M. , Walton N. A. , Yoldas A.
Published: June 2022

Context.GaiaData Release 3 contains astrometry and photometry results for about 1.8 billion sources based on observations collected by the European Space Agency (ESA)Gaiasatellite during the first 34 months of its operational phase (the same period covered byGaiaearly Data Release 3;GaiaEDR3). Low-resolution spectra for 220 million sources are one of the important new data products included in this release.

Aims.In this paper, we focus on the external calibration of low-resolution spectroscopic content, describing the input data, algorithms, data processing, and the validation of the results. Particular attention is given to the quality of the data and to a number of features that users may need to take into account to make the best use of the catalogue.

Methods.We calibrated an instrument model to relate meanGaiaspectra to the corresponding spectral energy distributions (SEDs) using an extended set of calibrators: this includes modelling of the instrument dispersion relation, transmission, and line spread functions. Optimisation of the model is achieved through total least-squares regression, accounting for errors inGaiaand external spectra.

Results.The resulting instrument model can be used for forward modelling ofGaiaspectra or for inverse modelling of externally calibrated spectra in absolute flux units.

Conclusions.The absolute calibration derived in this paper provides an essential ingredient for users ofBP/RPspectra. It allows users to connectBP/RPspectra to absolute fluxes and physical wavelengths.
Mesures et modélisation RF de capacités MIM intégrées
Authors: Arnould J.-D. , Podevin F. , Vincent L.
Published: June 2022

Il s’agit de former des étudiants de Master 2 et des ingénieurs en formation continue à la mesure RF sous pointes pour caractériser des capacités Métal-Isolant-Métal (MIM) intégrées sur un wafer. La problématique est d’obtenir le modèle électrique le plus fiable possible de ces capacités entre 40MHz et 26GHz tout en s’affranchissant des contraintes de mesures et des éléments d’accès RF à cette capacité.
Technologie additive : Impression de matériaux par jet d’encre pour l’électronique imprimée
Authors: Camara M. , Loganathan N. , Fischer A.
Published: June 2022

Nous présentons un enseignement sous forme de cours, Tps et projets tutorés sur le domaine de l’impression jet d’encre de matériaux pour l’électronique imprimée (réalisation de capteurs et d’OLED (organic light-emitting diode)). Nous aborderons avec les étudiants les enjeux de l’électronique imprimée comme fabrication additive ainsi que ses caractéristiques (Encre-Tête-Substrats). A travers les projets tutorés et les travaux pratiques, nous aborderons en salle blanche la technique de dépôt de matériaux par jets d’encres : de la conception à la caractérisation des couches imprimées en passant par la réalisation : traitement pré et post impression, mesure d’épaisseur et de résistivités d’encres conductrices.
Influence des paramètres puissance source et bias sur la gravure ICP-RIE plasma d’une couche mince suivie par interférométrie LASER
Authors: Constantin D. , Petit-Etienne C. , Bsiesy A.
Published: June 2022

Le CIME Nanotech, Centre Interuniversitaire de Microélectronique et Nanotechnologies, pôle du GIP CNFM (1) de Grenoble, répond aux besoins en formation expérimentale et pratique dans les domaines de la microélectronique et des nanotechnologies au travers de ces huit plateformes. L’offre de travaux pratiques sur la plateforme Salle Blanche, jusqu’alors orientée filière de fabrication de dispositifs micro- et nano-électroniques, propose désormais un travail pratique sur les plasmas appliqués à la gravure ionique réactive de couches minces sur un équipement de type industriel, suivie par interférométrie laser.
L’apprentissage par projet en microélectronique numérique Vers l’acquisition d’un savoir-faire
Authors: Lehouque G. , Costani A. , Portolan M. , Fesquet L.
Published: June 2022

Dans le cadre de la filière par apprentissage Microélectronique et Télécoms (MT) de l’école d’ingénieurs Phelma-Grenoble INP, les étudiants de seconde année effectuent un projet au sein du CIME Nanotech durant leur second semestre dont l’objectif est la conception d’un « digital baseband controler » pour la norme ZigBee. Ils sont ainsi confrontés à une situation très proche de celle qu’ils connaîtront en milieu industriel car la conception d’une puce nécessite, non seulement d’en imaginer les plans, mais aussi d’effectuer de très nombreuses vérifications garantissant la manufacturabilité du circuit intégré, étapes nécessaires avant d’envoyer un circuit en fabrication via le CMP (Circuits Multi-Projets). Ces vérifications, pourtant indispensables, sont rarement effectuées lors des apprentissages en école car ces étapes sont extrêmement chronophages et requièrent persévérance et ténacité. Enfin, l’organisation de l’équipe et la gestion des tâches aux quotidiens sont aussi des éléments clés du succès. Cet article relate cette aventure humaine et pédagogique unique vécue par dix étudiants de la filière MT de Phelma.
Mise en oeuvre de capteurs RF-MEMS acoustiques pour l’industrie 4.0
Authors: Dusch Y. , Ghouila Houri C. , Mazzamurro A. , Boussatour G. , Dahmani H. , Bou Matar O. , Maurice V. , Pernod P. , Talbi A.
Published: June 2022

Cette étude propose la conception complète d’un système de suivi à distance des sollicitations mécaniques dans les machines électriques afin de répondre aux problématiques de l’industrie 4.0 et de la maintenance prédictive. Elle s’appuie sur la conception, la fabrication et la caractérisation de MEMS acoustiques hautes fréquences (bande ISM à 433MHz) intégrés à un banc de test et comparés aux performances de jauges de déformation commerciales.
Mesures multiports de dispositifs passifs par analyseur de réseaux 4 ports
Authors: Fontana A. , Tantot O. , Delhote N. , Verdeyme S. , Barelaud B.
Published: June 2022

Dans cet article, la démarche est de proposer des activités de travaux pratiques et de projet sur la mesure de composants multipôles de Front End tels que les ponts diviseurs de Wilkinson et les circulateurs, en utilisant des analyseurs de réseaux 4 ports qui permettent une mesure vectorielle simultanée de la réponse fréquentielle en réflexion de chaque port et en transmission entre chaque port et des procédures de de-embedding des mesures.
Conception de système embarqué sur cible FPGA : une approche par compétences
Authors: Frick V. , Boyer B.
Published: June 2022

Cet article témoigne d’une expérience d’approche par compétence appliquée dans le cadre de modules d’enseignement aux systèmes électroniques embarqués. Les projets proposés aux étudiants visent à développer les compétences qui leur permettront de répondre efficacement à un cahier des charges dans un domaine où matériels et logiciels sont en constante évolution. En l’occurrence, il s’agit d’encourager l’initiative dans les choix techniques de co-conception de circuits numériques impliquant le langage de description matériel VHDL, la synthèse de processeur embarqué, la programmation en langage C. Le retour d’expérience montre qu’au prix d’un suivi régulier de la progression des étudiants, les résultats et le taux de satisfaction des étudiants sont très élevés et peuvent même dépasser les objectifs initiaux.
Système de surveillance de la qualité de l’air basé sur des capteurs embarqués sur vélo : projet AIR’O X AIR BREIZH
Authors: Méric S. , Nouvel F. , Agarini R. , Bunouf T. , Guellaen Q. , Le Bouhart G. , Meilhat M. , Chevé M. , Le Bihan O. , Le Méhauté K. , Leray S.
Published: June 2022

Cette communication décrit la réalisation d’un projet étudiant (projet Air’o) destiné au suivi de la pollution de l’air en collaboration avec l’association Air Breizh. Ce projet a été initié pendant l’année universitaire 2019-2020 lors de la 2ème année ingénieur (niveau M1) au sein du département « électronique et télécommunications » de l’INSA de Rennes. Le but du projet est de proposer une mesure de la qualité de l’air par l’intermédiaire de capteurs embarqués sur des vélos. Une transmission de la position du capteur ainsi que la mesure de pollution en temps réel via le réseau LoRaWAN (Long Range Wide-area Network) permet de localiser les niveaux de pollution tout au long du parcours du vélo. Ce suivi de la qualité de l’air s’effectue par la récupération des données (pollution, position) sur un serveur dédié. Une application spécifique est développée afin de situer géographiquement les niveaux de pollution enregistrés. La réalisation d’un prototype est présentée ainsi que la transmission des informations. Des premiers résultats indiquent la pertinence du concept développé.
Differentialtherapeutische Zugänge bei der prothetischen Versorgung von Fingergelenken
Authors: Labèr Raffael , Schindele Stephan Franz
Published: June 2022

Fortgeschrittene degenerative Veränderungen der Fingergelenke führen nicht selten zu chirurgischen Behandlungen unterschiedlicher Art. Dabei kommt neben der Arthrodese auch die bewegungserhaltende Therapie mittels eines Kunstgelenks in Frage. Hierfür kann der behandelnde Chirurg zwischen einer Vielzahl unterschiedlicher Zugänge wählen. Die verschiedenen Zugänge mit ihren charakteristischen intraoperativen Vor- und Nachteilen sowie für die postoperative Behandlung sollten patienten-, implantat- und nachbehandlungsspezifisch ausgewählt und angewendet werden. Im Folgenden wird eine Übersicht über die möglichen Zugänge sowie die damit einhergehenden Operationstechniken zum Fingergelenksersatz am Grund-, Mittel- und Endglied gegeben.
Clinical effectiveness of short course oral prednisone for stricture prevention after semi-circumferential esophageal endoscopic submucosal dissection
Authors: Arantes Vitor N. , Ramos Josué Aliaga , White Jonathan Richard , Parra-Blanco Adolfo
Published: June 2022

Background and study aims Esophageal strictures (ES) occur frequently after semi-circumferential endoscopic submucosal dissection (ESD) for the eradication of superficial esophageal neoplasms and negatively impact a patient’s quality of life. Oral corticosteroids have been shown to be clinically effective, but the most appropriate drug, dose and duration is yet to be determined. The aim of the study was to investigate the clinical effectiveness and safety of 30 mg prednisone with a shortened tapering schedule on ES after semi-circumferential ESD.

Patients and methods This was a retrospective observational study that analyzed consecutive patients with esophageal neoplasms who underwent semi-circumferential ESD with a resection defect greater than 75 % of the circumference that received a protocol of oral steroids for stricture prevention. On postoperative day 3, 30 mg prednisone was prescribed, tapering weekly to 20 mg/10 mg/5 mg over 4 weeks. Follow-up included clinic consultation and endoscopic review at weeks 2 and 4. Effectiveness outcomes included ES rates, safety, tolerability, resection, dilatation and recurrence rates.

Results Ninety ESD procedures were carried out during the specified time period and 18 patients met the inclusion criteria for the final analysis. The mean age was 61.5 years, lesion size was 52.5 mm, and final histology was squamous cell carcinoma in all patients. Incidence of intra-procedure complications was: bleeding 5.5 % (1/18) and ES 5.5 % (1/18), requiring a median two endoscopic dilatations. En bloc, R0 and curative resection rates were 88.8 %, 72.2 %, and 55.5 %, respectively.

Conclusions The short tapering schedule of 30 mg oral prednisone is clinically efficacious and safe for prevention of ES after semi-circumferential ESD in Latin American patients.
An international experience with single-operator cholangiopancreatoscopy in patients with altered anatomy
Authors: Mony Shruti , Ghandour Bachir , Raijman Isaac , Manvar Amar , Ho Sammy , Trindade Arvind J. , Benias Petros C. , Zulli Claudio , Jacques Jérémie , Ichkhanian Yervant , Zuchelli Tobias , Ghanimeh Mouhanna Abu , Irani Shayan , Canakis Andrew , Sanaei Omid , Szvarca Daniel , Zhang Linda , Bejjani Michael , Akshintala Venkata , Khashab Mouen A.
Published: June 2022

Background and study aims The utility of digital single- operator cholangiopancreatoscopy (D-SOCP) in surgically altered anatomy (SAA) is limited. We aimed to evaluate the technical success and safety of D-SOCP in patients SAA.

Patients and methods Patients with SAA who underwent D-SOCP between February 2015 and June 2020 were retrospectively evaluated. Technical success was defined as completing the intended procedure with the use of D-SOCP.

Results Thirty-five patients underwent D-SOCP (34 D-SOC, 1 D-SOP). Bilroth II was the most common type of SAA (45.7 %), followed by Whipple reconstruction (31.4 %). Twenty-three patients (65.7 %) patients had prior failed ERCP due to the presence of complex biliary stone (52.2 %). A therapeutic duodenoscope was utilized in the majority of the cases (68.6 %), while a therapeutic gastroscope (22.7 %) or adult colonoscope (8.5 %) were used in the remaining procedures. Choledocholithiasis (61.2 %) and pancreatic duct calculi (3.2 %) were the most common indications for D-SOCP. Technical success was achieved in all 35 patients (100 %) and majority (91.4 %) requiring a single session. Complex interventions included electrohydraulic or laser lithotripsy, biliary or pancreatic stent placement, stricture dilation, and target tissue biopsies. Two mild adverse events occurred (pancreatitis and transient bacteremia).

Conclusions In SAA, D-SOCP is a safe and effective modality to diagnose and treat complex pancreatobiliary disorders, especially in cases where standard ERCP attempts may fail.
Badge sign-in and report cards improve first case start times in gastrointestinal endoscopy: A prospective quality improvement study
Authors: Hiroshige Karina , Ferrer Alyssa , Chi Stephanie , Steineke Brittany , Hersch David , Goldbeck Jessica , Stiles Megan , Azeez Devina Adam , Tuzzolo Karen , Reisert Dolores , Fitzpatrick Maureen , Trindade Arvind J.
Published: June 2022

Background and study aims First case start (FCS) time is often a key metric used to gauge efficiency in an endoscopy suite. There are limited data on tools and methods to improve the FCS time in the endoscopy suite.

Methods A prospective observational cohort study was conducted in an academic tertiary care endoscopy suite examining the effect of badge sign-in (Period 2) and badge sign-in coupled with report cards (Period 3) compared to an initial observational period (Period 1).

Results After the badge sign-in reader was introduced in P2, the unit experienced a mean time savings of 5 ± 18 minutes in FCS delays compared to P1 (P = .03). In P3, an 8 ± 17-minute time savings in FCS time delay was observed compared to P1 (P = 0.0006). Sign-in compliance significantly increased for the overall unit between P2 and P3 (49 % vs. 59 %, P = .002). Increases in first case on-time start (FCOTS) rates compared to P1 were observed for the unit, with a 14% absolute increase in P2 (P < .0001) and a 17 % absolute increase in P3 (P < .0001). FCS delays for on-time badge sign-ins were significantly lower compared to FCS delays for missed badge sign-ins and late badge sign-ins (P < .0001).

Conclusions The use of badge sign-in and report cards improve endoscopy unit efficiency as it can increase FCOTS rates and decrease FCS time delays.
Zugänge bei Operationen einer Dupuytren’schen Kontraktur
Authors: Kalb Karlheinz , Schnegg Jakob Richard , Dimitrova Polina
Published: June 2022

Die Konzepte zur Behandlung der Dupuytrenschen Kontraktur differieren erheblich. Nichtsdestotrotz bleibt die partielle Aponeurektomie die operative Methode der Wahl bei fortgeschrittener Erkrankung. Ein wesentlicher Aspekt dieser Operation ist ein korrekter Zugangsweg. Unter Einbeziehung der Literatur erfolgt die Darstellung grundlegender Prinzipien, sowie des konkreten eigenen Vorgehens bei unterschiedlichen Ausgangsbefunden.

Voraussetzung für eine korrekte Operationsplanung und damit einer adäquaten Schnittführung ist neben sorgfältiger Anamnese eine subtile Erfassung des individuellen Befundes. Relevante Parameter sind Befundausdehnung und Hautqualität. Anerkannte Basisinzisionen sind an den Fingern Längsinzisionen mit Auflösung durch Z-Plastiken und Zick-Zack-Inzisionen mit vielen Variationen. Bei ausgeprägterem Hautdefizit kommen Lappenplastiken zum Einsatz. In der Hohlhand bevorzugen wir einen ulnarseitig gestielten Lappen, alternativ eine Hohlhand-Z-Plastik. Befundabhängig sind Kombinationen notwendig. Entscheidend ist die Beachtung handchirurgischer Prinzipien, suffiziente Exposition des Situs, Ausnutzung verschieblicher Hautareale und die Beachtung der Vaskularisation resultierender Hautlappen.

Bei komplexem Ausgangsbefund ist eine individualisierte Schnittführung unter Beachtung der handchirurgischen Grundprinzipien mit Ausgleich des antizipierten Hautdefizits ein wesentliches Element für den Erfolg des Eingriffes, wobei die konkrete Umsetzung bei erfahrenen Handchirurgen stark variieren kann.
Colorectal submucosa thickness in specimens obtained by EMR versus ESD: a retrospective pilot study
Authors: Clees Natalie , Várnai-Händel Alinda D. , Hildenbrand Ralf , Grund Karl-E. , Metter Klaus , Dumoulin Franz Ludwig
Published: June 2022

Accurate histopathology is the mainstay for reliable classification of resected early colorectal cancer lesions in terms of potential risk of lymph node metastasis. In particular, thickness of resected submucosa is important in cases of submucosal invasive cancer. Nevertheless, little is known about the quality and thickness of submucosal tissue obtained using different endoscopic resection techniques. In this small pilot study, we performed morphometric analysis of submucosal thickness in specimens obtained from right-sided colorectal lesions using endoscopic mucosal resection (EMR) versus endoscopic submucosal resection (ESD). Comparative measurements showed significant differences in submucosal area ≥ 1000 μm and minimum submucosal thickness per tissue section analyzed (EMR vs. ESD: 91.2 % ± 6.6 vs. 47.1 % ± 10.6, P = 0.018; 933.7 µm ± 125.1 vs. 319.0 µm ± 123.6, P = 0.009). In contrast, no significant differences were observed in variation coefficient and mean maximum submucosal thickness. Thus, unexpectedly, in this small retrospective pilot study, specimens obtained using EMR had a better preserved submucosal layer than those obtained using ESD – possibly due to the different methods of specimen acquisition. The findings should be kept in mind when attempting to resect lesions suspicious for submucosal invasive cancer.
Der Dünger zum Aufblühen – Selbstfürsorge
Authors: Holtmeier Lisa
Published: June 2022

Kaum jemand kommt auf die Idee, eine Pflanze unter Druck zu setzen, dass sie jetzt gefälligst blühen soll. Und doch tun Menschen dies – und zwar oft im Umgang mit sich selbst. Dabei sind sie ähnlich wie Pflanzen, die nur Pflege brauchen, um gut zu gedeihen, sich stabil zu verwurzeln und aufzublühen. Hier kommen eine kleine Pflegeanleitung und paar Rezepte für super Dünger, an dem es im Alltag oft fehlt.
Zu jung, zu schön, zu weiblich – Mediale Darstellung von Migräne
Authors: Kull Pia , Raffaelli Bianca
Published: June 2022

Oft werden Schmerzerkrankungen in den Medien klischeehaft dargestellt: gestylte Frauen und Männer, die mit leidendem Gesichtsausdruck die verschiedenen Arten von Schmerzen transportieren sollen. Auch bei der Migräne gibt es dieses Phänomen. Doch die verharmlosenden, realitätsfernen Darstellungen bergen die Gefahr, dass die Schwere der Erkrankung verschleiert wird und die soziale Stigmatisierung zu Stress und Frust führt.
Differentialtherapeutische Herangehensweisen zur Behandlung des Karpaltunnelsyndroms
Authors: Harhaus Leila , Daeschler Simeon C. , Aman Martin , Böcker Arne Hendrik , Klimitz Felix , Bickert Berthold
Published: June 2022

Das Karpaltunnelsyndrom (KTS) stellt die häufigste kompressionsbedingte Neuropathie dar. Die Therapieführung ist patientenindividuell zu gestalten. Die initiale konservative Therapie hat insbesondere im Anfangsstadium einen hohen Stellenwert. Die Indikation zur primären chirurgischen Therapie besteht bei therapierefraktären Situationen, ab mittelschweren Stadien oder bei Vorliegen relevanter Begleiterkrankungen (Raumforderungen, komplex regionalem Schmerzsyndrom, diabetische Polyneuropathie) und zunehmend auch beim KTS in der Schwangerschaft. Die unterschiedlichen Operationstechniken, deren differentialtherapeutische Anwendung, sowie deren Vor- und Nachteile sollen in dieser Arbeit pragmatisch dargestellt werden. Auch die herausfordernden Rezidivsituationen und -eingriffe werden hierbei herausgehoben. Vor dem Hintergrund der neu erschienenen aktualisierten S3-Leitlinie „Diagnostik- und Therapie des Karpaltunnelsyndroms“ hat dieser Themenbereich eine aktuelle Relevanz.
Differentialtherapeutische Zugänge zur Frakturversorgung an der Hand – Wann macht man was?
Authors: Pillukat Thomas , Mühldorfer-Fodor Marion , van Schoonhoven Jörg
Published: June 2022

Die Behandlung von Fingerfrakturen ist in doppelter Hinsicht anspruchsvoll. Fehlstellungen und Inkongruenzen von Gelenken führen häufig zu ernsthaften funktionellen Einschränkungen und sollten daher nicht toleriert werden. Auf der anderen Seite wird der operative Zugang zur Fraktur häufig durch die unmittelbare Nähe wichtiger Funktionsgewebe wie Nerven, Gefäße, Bandapparat und Sehnen begrenzt. Der vorliegende Artikel enthält eine Auswahl von Behandlungsmöglichkeiten, die sich nach Auffassung der Autoren vor dem Hintergrund einer großen Klinik bewährt haben mit Hinweisen auf alternative Verfahren und das Vorgehen in besonderen Situationen ohne Anspruch auf Vollständigkeit.
Ich hab mich gefreut wie ein Erwachsener – Ich-Zustände
Authors: Hertlein Margit
Published: June 2022

Eigentlich heißt es ja „sich freuen wie ein Kind“. Das vergessen wir Erwachsenen ab und an und freuen uns … na ja, etwas verhaltener, eben wie Erwachsene. Ein bisschen mehr Enthusiasmus und spielerische Freude haben aber durchaus ihre Berechtigung.
Die Ausbildung der Therapieberufe muss zukunftsfest sein – Kampagne zur Akademisierung
Authors: Borgetto Bernhard
Published: June 2022

Seit vielen Jahren ist sie ein Diskussionsthema, wenn es um die Weiterentwicklung der Therapieberufe in Deutschland geht: die Akademisierung. Das Bündnis Therapieberufe an die Hochschulen hat vor kurzem ihre Kampagne #zusammenTun gestartet. Ziel ist es, die Vollakademisierung in Deutschland voranzutreiben.
Endoscopic Injections of Botulinum Toxin Type A in the Piglet Esophagus Is Safe and Feasible but Did Not Result in any Significant Structural Changes 3 Days after Injection
Authors: Rose Morten , Clarke Patrick , Pike Ashton H. , Zvara Peter , Schrøder Henrik D. , Hejboel Eva K. , Qvist Niels , Ellebæk Mark B.
Published: June 2022

Introduction Treatment for long-gap esophageal atresia (LGEA) aims at achieving primary anastomosis with minimal tension. Previous studies have shown that intramural injections with botulinum toxin type-A (BTX-A) from the adventitial side can increase the elongation of the piglet and rat esophagus before bursting, and that this effect is dose and time dependent. Our aim was to determine if endoscopic injections would be feasible, safe, and with an effect on the mechanical properties of the esophagus.

Methods Twenty-two male piglets (5.15 kg) were randomized into two groups, one receiving 2 units/kg BTX-A, the other equal volume 0.9% NaCl. On day 3, the esophagus was harvested and tested in a stretch-tension machine to evaluate elongation and maximum load, followed by histological examination.

Results No adverse effects to the procedure were observed. No statistically significant difference in elongation or maximum load before bursting between the treatment and placebo group was found. In histopathological analysis, inflammation and abscess formation were observed with no statistically significant difference between the two groups.

Conclusion Endoscopic placement of BTX-A injections in the piglet esophagus was safe and feasible but did not result in any difference in the mechanical properties or histology of the esophagus.
Should an Age Cutoff Be Considered for Elective Total Knee Arthroplasty Patients? An Analysis of Operative Success Based on Patient-Reported Outcomes
Authors: Bell Joshua A. , Emara Ahmed K. , Barsoum Wael K. , Bloomfield Michael , Briskin Isaac , Higuera Carlos , Klika Alison K. , Krebs Viktor E. , Mesko Nathan W. , Molloy Robert M. , Mont Michael A. , Murray Trevor G. , Muschler George F. , Nickodem Robert J. , Patel Preetesh D. , Schaffer Jonathan L. , Stearns Kim L. , Strnad Gregory J. , Piuzzi Nicolas S.
Published: June 2022

Total knee arthroplasty (TKA) is increasing in the elderly population; however, some patients, family members, and surgeons raise age-related concerns over expected improvement and risks. This study aimed to (1) evaluate the relationship between age and change in patient-reported outcome measures (PROMs); (2) model how many patients would be denied improvements in PROMs if hypothetical age cutoffs were implemented; and (3) assess length of stay (LOS), readmission, reoperation, and mortality per age group. A prospective cohort of 4,396 primary TKAs (August 2015–August 2018) was analyzed. One-year PROMs were evaluated via Knee injury and Osteoarthritis Outcome Score (KOOS)-pain, -physical function short form (-PS), and -quality of life (-QOL), as well as Veterans Rand-12 (VR-12) physical (-PCS) and mental component (-MCS) scores. Positive predictive values (PPVs) of the number of postoperative “failures” (i.e., unattained minimal clinically important difference in PROMs) relative to number of hypothetically denied “successes” from a theoretical age-group restriction was estimated. KOOS-PS and QOL median score improvements were equivalent among all age groups (p = 0.946 and p = 0.467, respectively). KOOS-pain improvement was equivalent for ≥80 and 60–69-year groups (44.4 [27.8–55.6]). Median VR-12 PCS improvements diminished as age increased (15.9, 14.8, and 13.4 for the 60–69, 70–79, and ≥80 groups, respectively; p = 0.002) while improvement in VR-12 MCS was similar among age groups (p = 0.440). PPV for failure was highest in the ≥80 group, yet remained <34% for all KOOS measures. Overall mortality was highest in the ≥80 group (2.14%, n = 9). LOS >2, non-home discharge, and 90-day readmission were highest in the ≥80 group (8.11% [n = 24], p < 0.001; 33.7% [n = 109], p < 0.001; and 34.4% [n = 111], p = 0.001, respectively). Elderly patients exhibited similar improvement in PROMs to younger counterparts despite higher LOS, non-home discharge, and 90-day readmission. Therefore, special care pathways should be implemented for those age groups.
Supine Knee Positioning Does Not Interfere with Mobile-Bearing Unicompartmental Knee Arthroplasty Performance
Authors: Bonano John C. , Barrett Andrew A. , Aggarwal Vinay K. , Chen Foster , Schirmers Joseph , Finlay Andrea K. , Arora Prerna , Amanatullah Derek F.
Published: June 2022

The Food and Drug Administration has only approved mobile-bearing unicompartmental knee arthroplasty (MB-UKA) to be performed with a hanging leg holder. The purpose of this study is to evaluate the impact of a supine knee position on MB-UKA performance.

In total, 16 cadavers were randomized so that either the right or left knee was placed in the flexed or supine positions. One board-certified orthopaedic surgeon and three adult reconstruction fellows that attended the required Oxford partial knee instructional course performed four operations in each position. The primary outcome was final knee balance. Secondary outcomes included procedure duration, timing of individual surgical steps, implant sizes, range of motion, implant alignment, and fracture. A Students t-test was used to examine differences between positions with significance set at p < 0.05. Secondary analyses using two one-sided tests were conducted to explore equivalence between the two positions.

There was no significant difference in mean final balance between supine (1.7 mm ± standard deviation [SD] = 1.5 mm) and flexed (1.3 ± 1.3 mm) positions (p = 0.390). There were also no significant differences between positions for procedure time (p = 0.497), tibia coronal alignment (p = 0.614), tibial slope (p = 0.194), femoral component sagittal alignment (p = 0.091), and fractures (n = 0). Exploratory equivalence analyses indicated that the positions were equivalent for final balance (p = 0.002).

MB-UKA performed in the supine position is not significantly different from the flexed position in terms of ligament balance, overall procedure time, and radiographic appearance. These initial safety data warrant further clinical investigations and support the expansion of the surgical technique to include performing MB-UKAs in the supine position.
Laparoscopic versus Open Reduction of Intussusception in Infants and Children: A Systematic Review and Meta-analysis
Authors: Wu Peng , Huang Ping , Fu Yijia , Lv Yaxin , Feng Shaoguang , Lou Yi
Published: June 2022

We conducted a systematic review and meta-analysis to compare the efficacy and safety between laparoscopic reduction (LR) and open reduction (OR) of intussusception in infants and children. Literature searches were conducted to identify studies having compared LR and OR for children with intussusception failed to enema reduction. Parameters such as operative time, time to oral intake, length of hospital stay, overall postoperative complications, and recurrence were pooled and compared by meta-analysis. Among the 502 pediatric participants included in the 11 studies, 275 had received LR and 227 received OR. There were shorter length of hospital stays and time to oral intake with the LR approach compared with OR. However, no significant difference was found between LR and OR in the secondary outcome, such as the overall postoperative complications and recurrence. LR is a feasible, safe, and effective surgical procedure alternative to OR for pediatric intussusception. Compared with OR, LR has the advantage of shorter hospital stay and faster time to oral intake. Besides, the overall postoperative complications may be slightly lower in LR. We conclude that LR should be considered an acceptable option for children.
Krankenhausplan Nordrhein-Westfalen 2022: Mindestmerkmale statt Betten
Authors: Bornemeier Olaf
Published: June 2022

Nordrhein-Westfalen macht ernst. Am 25. April des Jahres hat der Krankenhausplan NRW 2022 Rechtskraft erlangt. Er stellt dabei nicht weniger als einen Paradigmenwechsel gegenüber den bisherigen Planungsmethoden dar.
Pflegemangel: Rund eine halbe Million mehr Pflegekräfte, wenn ...
Authors: Heeser Alexandra
Published: June 2022

… sich die Arbeitsbedingungen verbessern: mehr Personal, verlässliche Arbeitszeiten und eine bessere Bezahlung. Das zeigt eine bundesweite Studie der Arbeitnehmerkammer Bremen, in Kooperation mit der Arbeitskammer des Saarlandes und dem Institut Arbeit und Technik der Westfälischen Hochschule.
Managerin des Jahres 2021: Alena Buyx: Ein Leben auf der Überholspur
Authors: Orth Anne
Published: June 2022

Zwei Aufgaben gleichzeitig zu bewältigen – das ist für Prof. Dr. med. Alena Buyx eine der leichteren Übungen. Herausfordernd ist für sie erst, zeitgleich drei oder vier Anforderungen zu stemmen. Seit 2018 ist Buyx Professorin für Ethik der Medizin und Gesundheitstechnologien an der Medizinischen Fakultät der Technischen Universität München. Im Mai 2020 wurde sie zusätzlich zur Vorsitzenden des Deutschen Ethikrats gewählt, und steht seitdem stark in der Öffentlichkeit.
Dedalus: Herausforderer mit Verkaufsschild
Authors: Doelfs Guntram
Published: June 2022

Dedalus-CEO Andrea Fiumicelli will sein Unternehmen zum führenden Health-IT-Anbieter in Europa machen und treibt die Expansion energisch voran. Das kühne Vorhaben könnte nun jedoch möglicherweise einen Dämpfer bekommen. Die Private-Equity-Beteiligungsgesellschaft Ardian, bislang Mehrheitseigner des Health-IT-Riesen, plant offenbar den Verkauf von Dedalus.
Kliniken Köln: Das Land spielt auf Zeit
Authors: Rößing Sabine
Published: June 2022

Die Turbulenzen bei den Kliniken Köln nehmen zu. Seit Jahren kommt die ins Auge gefasste Fusion mit dem Kölner Uniklinikum nicht vom Fleck, die Finanzsituation bei den hoch defizitären Kliniken ist schwierig. Nun tauschen die Kliniken auch noch binnen weniger Wochen beinahe ihre komplette Führungsspitze aus. Die Stadt Köln muss endlich eine Lösung finden – entweder die Fusion, einen anderen Partner oder eine harte Sanierung.
Zeitarbeit: Flexibel und anpassungsfähig
Authors: Lang Michael
Published: June 2022

Der Fachkräftemangel in der Pflege hat dazu geführt, dass Kliniken verstärkt Zeitarbeiter einsetzen. Über die aktuelle Situation der Branche in den Krankenhäusern berichtet eine Personalberaterin und Geschäftsführerin einer Zeitarbeitsfirma.
Hybrid-DRG Thüringen: Neue Wege entstehen beim Gehen
Authors: Dittrich Stephan
Published: June 2022

Das Projekt „Sektorenunabhängige Versorgung in der Chirurgie mit dem Pilotprojekt „Hybrid-DRG Thüringen – Neue Wege im Gesundheitswesen“ ist ein Konzept, welches aufzeigt, wie eine sektorenunabhängige Versorgung gestaltet werden kann, und ist somit eine Alternative zu den bisherigen strukturell und finanziell sowie ökonomisch getriggerten Versorgungsansätzen.
Revealing dynamic processes in laser powder bed fusion with in situ X-ray diffraction at PETRA III
Authors: Krohmer Erwin , Schmeiser Felix , Wahlmann Benjamin , Rosigkeit Jan , Graf Gloria , Spoerk-Erdely Petra , Clemens Helmut , Staron Peter , Körner Carolin , Reimers Walter , Uhlmann Eckart
Published: June 2022

The high flux combined with the high energy of the monochromatic synchrotron radiation available at modern synchrotron facilities offers vast possibilities for fundamental research on metal processing technologies. Especially in the case of laser powder bed fusion (LPBF), an additive manufacturing technology for the manufacturing of complex-shaped metallic parts, in situ methods are necessary to understand the highly dynamic thermal, mechanical, and metallurgical processes involved in the creation of the parts. At PETRA III, Deutsches Elektronen-Synchrotron, a customized LPBF system featuring all essential functions of an industrial LPBF system, is used for in situ x-ray diffraction research. Three use cases with different experimental setups and research questions are presented to demonstrate research opportunities. First, the influence of substrate pre-heating and a complex scan pattern on the strain and internal stress progression during the manufacturing of Inconel 625 parts is investigated. Second, a study on the nickel-base superalloy CMSX-4 reveals the formation and dissolution of γ′ precipitates depending on the scan pattern in different part locations. Third, phase transitions during melting and solidification of an intermetallic γ-TiAl based alloy are examined, and the advantages of using thin platelet-shaped specimens to resolve the phase components are discussed. The presented cases give an overview of in situ x-ray diffraction experiments at PETRA III for research on the LPBF technology and provide information on specific experimental procedures.
New shapemeter roll technology based on Fiber Bragg Grating technology for on-line flatness monitoring of thin cold rolled metal sheets
Authors: Magne S. , Legrand N. , Ertz S. , Jouvin G. , André V. , Laffont G. , Boissonnet L.
Published: June 2022

The shape of laminated products is a crucial parameter in high-speed and high-volume finishing lines where they must fulfill tight tolerances. Latent defects are detected by flatness rolls (or shapemeter rolls) inserted in the manufacturing line for online flatness control. A prototype of flatness roll has been developed with high spatial resolution (5 mm) and measurement capability over a thickness range of 0.1–1 mm to evaluate flatness and residual stresses of flat metal strip products manufactured by continuous cold rolling (ultra-thin sheets for packaging and automotive markets). The flatness roll prototype relies on pressure-induced strain sensing on segmented blades using Fiber Bragg Grating technology. Synchronous measurement of the flatness profile across strip width rejects disturbances of strip tension during rolling. We provide a proof-of-concept on pilot lines in both static and dynamic conditions (e.g., roll in rotation and in contact with a strip under tension) and the sensing mechanism shows a capability above 3. This combination of performances remains unique up to now. Interblade crosstalk appears to be an important issue. We propose a crosstalk model that agrees with experimental coupling coefficients. A crosstalk matrix inversion yields the distribution in contact pressure from strain data measured on the reverse side. Additional work will be required to use the flatness roll in industrial conditions.