bluuebunny/crossref_metadata_2025 huggingface dataset:
Metal‐Catalyzed Etching of Vertically Aligned Polysilicon and Amorphous Silicon Nanowire Arrays by Etching Direction Confinement
Authors: Chang Shih‐wei , Chuang Vivian P. , Boles Steven T. , Thompson Carl V.
Published: September 2010

A systematic study of metal‐catalyzed etching of (100), (110), and (111) silicon substrates using gold catalysts with three varying geometrical characteristics: isolated nanoparticles, metal meshes with small hole spacings, and metal meshes with large hole spacings is carried out. It is shown that for both isolated metal catalyst nanoparticles and meshes with small hole spacings, etching proceeds in the crystallographically preferred <100> direction. However, the etching is confined to the single direction normal to the substrate surface when a catalyst meshes with large hole spacings is used. We have also demonstrated that the metal catalyzed etching method when used with metal mesh with large hole spacings can be extended to create arrays of polycrystalline and amorphous vertically aligned silicon nanowire by confining the etching to proceed in the normal direction to the substrate surface. The ability to pattern wires from polycrystalline and amorphous silicon thin films opens the possibility of making silicon nanowire array‐based devices on a much wider range of substrates.
An Unprecedented Silver Salt Effect Switches the Facial Selectivity in the Vinylogous Mukaiyama Aldol Reaction
Authors: Liang Yufan , Wang Lin , Zhu Rong , Deng Lujiang , Yang Yunfang , Quan Junmin , Chen Jiahua , Yang Zhen
Published: September 2010

Silver hexafluroantimonate was identified as a highly efficient agent to reverse the facial selectivity of the titanium chloride‐mediated vinylogous Mukaiyama aldol reaction (VMAR), and this unprecedented reaction provides a concise, diastereoselective synthesis of δ‐hydroxy‐α,γ‐dimethyl‐α,β‐unsaturated carbonyl units from readily available chiral vinylketene silyl N,O‐acetal 6 and ethyl glyoxylate 8.
Chemoenzymatic Synthesis of Both Enantiomers of 2‐tert‐Butyl‐2‐methyl‐1,3‐benzodioxole‐4‐carboxylic (TBMB) Acid
Authors: Higashi Toshinori , Abe Chika , Ninomiya Keiko , Machida Takuya , Chishima Nobuyuki , Taketomi Shohei , Furuta Miyu , Komaki Yoko , Senba Yoshihiko , Tokuda Taeko , Shoji Mitsuru , Sugai Takeshi
Published: September 2010

Both enantiomers of 2‐tert‐butyl‐2‐methyl‐1,3‐benzodioxole‐4‐carboxylic (TBMB) acid, which has a unique quaternary chiral center located on the acetal carbon, were prepared from a racemic ketone in which the carboxy group was replaced by a trifluoroacetyl group. First, reduction with fungi, Geotrichum candidum provided (2S,1′S)‐ and (2R,1′S)‐ 1′‐(2‐tert‐butyl‐2‐methyl‐1,3‐benzodioxol‐4‐yl)‐2′,2′,2′‐trifluoroethanol in a highly enantiofacially selective manner. After acetylation, the resulting diastereomeric mixture was submitted to Candida antarctica lipase B‐catalyzed transesterification. The reaction proceeded in a stereoselective manner under the influence of the chiral center at the acetal carbon, even though it was six atoms removed from the ester carbonyl carbon. Although the two substrates had the same absolute configuration at the secondary alcohol, the reaction rate of one stereoisomer was 72 times greater than that of the other isomer. The reason for this differential reactivity was attributed mainly to a large difference in Vmax(app) between the stereoisomers. The products, acetate and alcohol, were easily separated by chromatography, and each was then derivatized to (R)‐ and (S)‐TBMB acid, with >99.2% ee, respectively.
Iridium‐Catalyzed Hydrohydroxyalkylation of Butadiene: Carbonyl Crotylation
Authors: Zbieg Jason R. , Fukuzumi Takeo , Krische Michael J.
Published: September 2010

Exposure of alcohols 1a–1i to butadiene in the presence of a cyclometallated iridium catalyst derived from allyl acetate, 4‐methoxy‐3‐nitrobenzoic acid and 2,2′‐bis(diphenylphosphino)biphenyl (BIPHEP) results in hydrogen transfer to generate aldehyde‐allyliridium pairs, which engage in CC coupling to form products of carbonyl crotylation. Under related conditions using 1,4‐butanediol as hydrogen donor, butadiene reductively couples to aldehydes 2e–2g and 2i to furnish carbonyl crotylation products 3e–3g and 3i. Thus, butadiene‐mediated carbonyl crotylation occurs with equal facility from the alcohol or aldehyde oxidation level with complete levels of branched regioselectivity.
Relationships between serial childhood adiposity measures and adult blood pressure: The Fels longitudinal study
Authors: Sabo Roy T. , Lu Zheng , Daniels Stephen , Sun Shumei S.
Published: September 2010

Objectives: Several studies have shown that causes of adult hypertension arise in childhood, and obesity may be a potential cause or at least a mitigating factor in this development. Body mass index is a well studied obesity metric, yet other potential adiposity measures such as percent body fat and waist circumference have been somewhat less considered. The purpose of this study is to determine associations between these alternative serial childhood adiposity measures and adulthood blood pressure.

Methods: Measurements from participants in the Fels Longitudinal Study were used to summarize childhood adiposity, represented by childhood measurements of percent body fat and height‐adjusted waist circumference. These subjects also provided systolic and diastolic blood pressure as adults. Childhood adiposity levels were categorized as high or low as compared to the respective upper quartile, and associations with adult blood pressure were measured using Poisson regression to estimate the number of expected occurrences of elevated adiposity during childhood. Adult lifestyle covariates and adiposity were accounted for using multiple linear regression.

Results: Summary indices of the childhood adiposity measures were significantly associated with both adult blood pressure metrics in men and women, though some of these associations were altered or reduced in the presence of adult lifestyle characteristics and adult adiposity measures.

Conclusions: Childhood measures of percent body fat and height‐adjusted waist circumference have an effect on adult blood pressure, though the effect can be mitigated by adult lifestyles. Am. J. Hum. Biol., 2010. © 2010 Wiley‐Liss, Inc.
Emotions, stress, and maternal motivation in primates
Authors: Maestripieri Dario
Published: September 2010

Recent research conducted with nonhuman primates confirms that adaptive emotional processes, such as maternal attraction arousability and maternal anxiety arousability, enhance and sustain female motivation to interact with infants, invest in them, and protect them during the postpartum period. Changes in these emotional processes, and concomitant changes in maternal motivation, facilitate the reduction and eventual termination of maternal investment associated with infant weaning. Although laboratory studies of rodents and socially deprived rhesus monkeys have suggested that nulliparous females are neophobic and find infant stimuli aversive, recent primate research indicates that neophobia or aversion to infant stimuli do not occur in females with normal developmental experience. Furthermore, although some rodent and human studies have shown that lactation is accompanied by physiological hyporesponsiveness to stress, other studies of rodents, nonhuman primates, and humans indicate that mothers are highly vulnerable to stress and that stress‐induced dysregulation of emotions can interfere with maternal motivation and parenting behavior. It is possible that some aspects of the emotional and experiential regulation of maternal motivation and parental behavior are different in different mammalian species. However, variation in the environments in which subjects are tested and in their developmental experience may also be responsible for the some discrepancies between the results of different studies. Am. J. Primatol. 73:516–529, 2011. © 2010 Wiley‐Liss, Inc.
Prediction of malignant middle cerebral artery infarction by magnetic resonance imaging within 6 hours of symptom onset: A prospective multicenter observational study
Authors: Thomalla Götz , Hartmann Frank , Juettler Eric , Singer Oliver C. , Lehnhardt Fritz‐Georg , Köhrmann Martin , Kersten Jan F. , Krützelmann Anna , Humpich Marek C. , Sobesky Jan , Gerloff Christian , Villringer Arno , Fiehler Jens , Neumann‐Haefelin Tobias , Schellinger Peter D. , Röther Joachim ,   for the Clinical Trial Net of the German Competence Network Stroke
Published: September 2010

Objective

Early identification of patients at risk of space‐occupying “malignant” middle cerebral artery (MCA) infarction (MMI) is needed to enable timely decision for potentially life‐saving treatment such as decompressive hemicraniectomy. We tested the hypothesis that acute stroke magnetic resonance imaging (MRI) predicts MMI within 6 hours of stroke onset.

Methods

In a prospective, multicenter, observational cohort study patients with acute ischemic stroke and MCA main stem occlusion were studied by MRI including diffusion‐weighted imaging (DWI), perfusion imaging (PI), and MR‐angiography within 6 hours of symptom onset. Multivariate regression analysis was used to identify clinical and imaging predictors of MMI.

Results

Of 140 patients included, 27 (19.3%) developed MMI. The following parameters were identified as independent predictors of MMI: larger acute DWI lesion volume (per 1 ml odds ratio [OR] 1.04, 95% confidence interval [CI] 1.02–1.06; p < 0.001), combined MCA + internal carotid artery occlusion (5.38, 1.55–18.68; p = 0.008), and severity of neurological deficit on admission assessed by the National Institutes of Health Stroke Scale score (per 1 point 1.16, 1.00–1.35; p = 0.053). The prespecified threshold of a DWI lesion volume >82 ml predicted MMI with high specificity (0.98, 95% CI 0.94–1.00), negative predictive value (0.90, 0.83–0.94), and positive predictive value (0.88, 0.62–0.98), but sensitivity was low (0.52, 0.32–0.71).

Interpretation

Stroke MRI on admission predicts malignant course in severe MCA stroke with high positive and negative predictive value and may help in guiding treatment decisions, such as decompressive surgery. In a subset of patients with small initial DWI lesion volumes, repeated diagnostic tests are required. ANN NEUROL 2010
Reactivity of alkoxysilyl compounds: chemical surface modification of nano‐porous alumina membrane using alkoxysilylazobenzenes
Authors: Kakiage Kenji , Yamamura Masaki , Ido Erika , Kyomen Toru , Unno Masafumi , Hanaya Minoru
Published: September 2010

In order to clarify the chemical adsorption properties of alkoxysilyl compounds to metal‐oxide surface quantitatively and to obtain the information on the reaction conditions for the efficient surface modification, the chemical surface modifications of nano‐porous alumina membranes (NPAMs) by typical alkoxysilyl compounds of 4‐(triethoxysilyl)azobenzene, 4‐(diethoxyphenylsilyl)azobenzene, 4‐(ethoxydiphenylsilyl)azobenzene and 4‐(methoxydimethylsilyl)azobenzene were examined. The chemical surface modifications were performed by immersing NPAMs into the solutions of the alkoxysilylazobenzenes. Especially for 4‐(triethoxysilyl)azobenzene, the modification was investigated precisely by changing the solvent, temperature, concentration and water content of the solutions to reveal the effects of the reaction conditions on the adsorption property of alkoxysilyl compounds to metal oxides. The NPAMs having chemically modified surface were prepared successfully by the immersing method, and the alkoxysilylazobenzenes were confirmed to be bound on the NPAM surface through SiOAl bonds, which were indicated to be formed mainly by the direct condensation reaction between the alkoxysilyl groups of the azobenzenes and the hydroxy groups on the NPAM surface. The amounts of the azobenzenes adsorbed on the NPAM surface were estimated quantitatively by a visible absorption spectroscopy, and the results showed that the solutions with non‐polar solvents, higher temperatures and higher concentrations are suitable for the efficient surface modification. Copyright © 2010 John Wiley & Sons, Ltd.
Wood–polymer composites prepared by the in situ polymerization of monomers within wood
Authors: Li Yong‐Feng , Liu Yi‐Xing , Wang Xiang‐Ming , Wu Qing‐Lin , Yu Hai‐Peng , Li Jian
Published: September 2010

Wood–polymer composites (WPCs) were prepared from poplar wood (P.
ussuriensis Komarov) in a two‐step procedure. Maleic anhydride (MAN) was first dissolved in acetone and impregnated into wood; this was followed by a heat process; and then, glycidyl methacrylate (GMA) and styrene (St) were further impregnated into the MAN‐treated wood, followed by a second thermal treatment. Finally, the novel WPC was fabricated. The reactions occurring in the WPC, the aggregation of the resulting polymers, and their interaction with the wood substrate were analyzed by scanning electron microscopy, Fourier transform infrared spectroscopy, X‐ray diffraction, and dynamic mechanical analysis. The performance of WPC was also evaluated in terms of the mechanical properties and durability, which were then correlated with the structural analysis of the WPC. The test results show that MAN and GMA/St chemically reacted with the wood cell walls in sequence, and the quantity of hydroxyl groups in the wood cell walls was evidently reduced. Meanwhile, St copolymerized with GMA or MAN, and the resulting polymers mainly filled in the wood cell lumen in an amorphous form, tightly contacting the wood cell walls without noticeable gaps. As a result, the mechanical properties, decay resistance, and dimensional stability of the WPC were remarkably improved over those of the untreated wood, and its glass‐transition temperature also increased. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Preclinical comparison of intravenous melphalan pharmacokinetics administered in formulations containing either (SBE)7 m‐β‐cyclodextrin or a co‐solvent system
Authors: Koltun Maria , Morizzi Julia , Katneni Kasiram , Charman Susan A. , Shackleford David M. , McIntosh Michelle P.
Published: September 2010

The aim of this work was to evaluate the impact of sulfobutyl ether β‐cyclodextrin ((SBE)7 m‐β‐CD; Captisol®) on the in vivo pharmacokinetics of melphalan in rats. Melphalan is a chemically unstable antineoplastic drug which in the current commercial formulation (Alkeran® for Injection) has some limitations with regard to solubility, stability and biocompatibility. Melphalan formulations containing (SBE)7 m‐β‐CD have previously been evaluated in vitro and shown to significantly reduce the rate of degradation and to simplify the reconstitution procedure for lyophilised melphalan. In this study, melphalan was administered intravenously in rats in formulations that either contain (SBE)7 m‐β‐CD or a co‐solvent system (i.e. the commercial formulation). Pharmacokinetic parameters, including half‐life, volume of distribution, clearance and extent of renal elimination of melphalan were essentially unchanged between the two formulations. These findings indicate that the pharmacokinetics of melphalan are not altered in the presence of (SBE)7 m‐β‐CD consistent with a rapid shift in the equilibrium to the fully dissociated drug from the fraction associated with the cyclodextrin host molecule upon intravenous administration. Copyright © 2010 John Wiley & Sons, Ltd.
Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): Environmental connection
Authors: Toppari Jorma , Virtanen Helena E. , Main Katharina M. , Skakkebaek Niels E.
Published: September 2010

Cryptorchidism and hypospadias are common genital birth defects that affect 2–9% and 0.2–1% of male newborns, respectively. The incidence of both defects shows large geographic variation, and in several countries increasing trends have been reported. The conditions share many risk factors, and they are also interlinked to the risk of testis cancer and poor semen quality. Testicular Dysgenesis Syndrome (TDS) may underlie many cases of all these male reproductive health problems. Genetic defects in androgen production or action can cause both cryptorchidism and hypospadias, but these are not common. A monogenic reason for cryptorchidism or hypospadias has been identified only in a small proportion of all cases. Environmental effects appear to play a major role in TDS. Exposure to several persistent chemicals has been found to be associated with the risk of cryptorchidism, and exposure to anti‐androgenic phthalates has been shown to be associated with hormonal changes predisposing to male reproductive problems. Despite progress in identification of endocrine‐disrupting substances, we are still far from knowing all the risk factors for these birth defects, and advice for prevention must be based on precautionary principles. Birth Defects Research (Part A), 2010. © 2010 Wiley‐Liss, Inc.
Surface‐enhanced Raman scattering and theoretical studies of the C‐terminal peptide of the β‐subunit human chorionic gonadotropin without linked carbohydrates
Authors: Aliaga A. E. , Aguayo T. , Garrido C. , Clavijo E. , Hevia E. , Gómez‐Jeria J. S. , Leyton P. , Campos‐Vallette M. M. , Sanchez‐Cortes S.
Published: September 2010

Raman and surface‐enhanced Raman scattering (SERS) spectra of the synthetic carboxy terminal peptide of human chorionic gonadatropin β‐subunit free of carbohydrate moieties (P37) are reported. The spectral analysis is performed on the basis of our reported Raman spectrum and SERS data of oligopeptides displaying selected amino acids sequences MRKDV, ADEDRDA, and LGRGISL. SERS samples of P37 were prepared by coating the solid peptide with metal colloids on a quartz slide. This treatment makes possible to obtain high spectral batch to batch reproducibility. Amino acids components of P37 display net charges and hydrophobic characteristics, which are related to particular structural aspects of the adsorbate–substrate interaction. The spectroscopic results are supported by quantum chemical calculations performed by using extended Hückel theory method for a model of P37 interacting with an Ag surface. The P37‐metal interaction is drove by positively charged fragments of selected amino acids, mainly threonine 109, lysine 122, and arginine in positions 114 and 133. Data here reported intend to contribute to the knowledge about the antigen–antibody interaction and to the drugs delivery research area. © 2010 Wiley Periodicals, Inc. Biopolymers 95: 135–143, 2011.
Group psychoeducation for long‐term offender patients with schizophrenia: An exploratory randomised controlled trial
Authors: Aho‐Mustonen Kati , Tiihonen Jari , Repo‐Tiihonen Eila , Ryynänen Olli‐Pekka , Miettinen Raili , Räty Hannu
Published: September 2010

Background Psychoeducation is now commonly provided in forensic settings, but its effectiveness among long‐term offender patients with schizophrenia has not yet been established in randomised controlled trials (RCTs).

Aim To test the effects of a brief group psychoeducation programme for offenders with schizophrenia (n = 39) resident in a high‐security hospital (Niuvanniemi Hospital, Finland).

Method High‐security hospital patients were randomised into either eight sessions of group psychoeducation or ‘treatment as usual’ (TAU). Outcome measures, made at baseline, immediately post‐treatment, and 3 months after that, included knowledge about illness, insight, compliance, attitudes towards medication, psychiatric symptoms and ward behaviour, self‐esteem, health‐related quality of life and perceived stigma.

Results Three months after completing treatment, or an equivalent time under TAU, patients in the intervention group showed a positive treatment effect in terms of knowledge about illness, self‐esteem and insight into the illness. The only possible adverse effect was a slight increase in irritability, but this did not translate into behaviour of concern to staff.

Conclusions Our sample size was small, and the findings must be regarded as preliminary, but the positive treatment effect of psychoeducation, and the absence of alarming side effects, suggests a full scale trial would be worthwhile. Most encouraging was that even the most severely ill patients were able to join the groups. Copyright © 2010 John Wiley & Sons, Ltd.
FRET Studies on a Series of BODIPY‐Dye‐Labeled Switchable Resorcin[4]arene Cavitands
Authors: Pochorovski Igor , Breiten Benjamin , Schweizer W. Bernd , Diederich François
Published: September 2010

A series of borondipyrromethane (BODIPY)‐dye‐labeled resorcin[4]arene cavitands 1–4 with different lengths of oligo(phenylene–ethynylene) spacers between the dyes and the macrocyclic rim has been synthesized. Their switching behavior from the “vase” to “kite” conformations in bulk solution was examined by both variable‐temperature (VT) NMR and fluorescence spectroscopy. Both VT‐NMR and VT fluorescence resonance energy transfer (FRET) experiments showed that cavitands 1–4 undergo vase‐to‐kite switching at low temperatures. Acid‐triggered switching to the kite conformation was observed by fluorescence spectroscopy. Quantitative evaluation of the FRET data led to the determination of the Förster radius R0=37 Å for the BODIPY‐dye FRET pair and an average cavitand opening angle α=16° in the vase conformation.
ChemInform Abstract: Crystal Structure and Physical Properties of the Quaternary Manganese‐Bearing Pavonite Homologue Mn1.34Sn6.66Bi8Se20.
Authors: Anglin Clarence , Takas Nathan , Callejas Juan , Poudeu Pierre F. P.
Published: September 2010

The title compound is prepared by solid state reaction of the elements (773 K, 72 h) and characterized by single crystal XRD, magnetic susceptibility, thermal and electrical conductivity, thermopower, and IR measurements.
ChemInform Abstract: Phase Relations and Structural Properties of the Ternary Narrow Gap Semiconductors Zn5Sb4In2‐δ (δ = 0.15) and Zn9Sb6In2.
Authors: Wu Yang , Tengaa Andreas , Lidin Sven , Haeussermann Ulrich
Published: September 2010

The Zn‐rich section of the Zn—Sb—In system contains two ternary intermetallic compounds, stable Zn5Sb4In1.85 (I) and metastable Zn9Sb6In2 (II), with closely related crystal structures which are determined by single crystal XRD.
ChemInform Abstract: Synthesis, Characterization, and Quantum‐Chemical Studies of Ni(CN)2MX (M: Rb, Cs; X: Cl, Br).
Authors: Liu Xiaohui , Speldrich Manfred , Koegerler Paul , Dronskowski Richard , Tchougreeff Andrei L.
Published: September 2010

The new two‐dimensional compounds (III) are characterized by single crystal XRD, FT‐IR and UV/VIS spectroscopy, magnetic measurements, and DFT calculations.
ChemInform Abstract: Controlling Stereoselectivity in the Aminocatalytic Enantioselective Mannich Reaction of Aldehydes with in situ Generated N‐Carbamoyl Imines.
Authors: Galzerano Patrizia , Agostino Dario , Bencivenni Giorgio , Sambri Letizia , Bartoli Giuseppe , Melchiorre Paolo
Published: September 2010

An asymmetric anti‐selective Mannich reaction of in situ generated N‐carbamoyl imines with aldehydes is achieved in the presence of diarylprolinol Tms ethers as catalysts.
ChemInform Abstract: One‐Pot Construction of Multiple Contiguous Chiral Centers Using Michael Addition of Chiral Amine.
Authors: Ozeki Minoru , Ochi Shunsuke , Hayama Noboru , Hosoi Shinzo , Kajimoto Tetsuya , Node Manabu
Published: September 2010

Tandem Michael—aldol, double Michael, and double Michael—aldol reactions with the chiral amine (I) allow efficient and stereoselective access to functionalized amines with up to five contiguous chiral centers in one pot.
ChemInform Abstract: Supported Cobalt Complex‐Catalyzed Conjugate Addition of Indoles, Amines and Thiols to α,β‐Unsaturated Compounds.
Authors: Rajabi Fatemeh , Razavi Sepideh , Luque Rafael
Published: September 2010

A supported cobalt complex is successfully used as a reusable catalyst for the Michael addition of thiols (I), amines (VI), and indoles (VIII) to alkenes (II) and (IV) under solvent‐free conditions.
ChemInform Abstract: [2 + 2] Cycloaddition of Electron‐Poor Acetylenes to (E)‐3‐Dimethylamino‐1‐heteroaryl‐prop‐2‐en‐1‐ones: Synthesis of Highly Functionalized 1‐Heteroaroyl‐1,3‐butadienes.
Authors: Bezensek Jure , Kolesa Tanja , Groselj Uros , Wagger Jernej , Stare Katarina , Meden Anton , Svete Jurij , Stanovnik Branko
Published: September 2010

Substrates (I) undergo a microwave‐promoted cycloaddition with DMAD to give cyclobutene intermediates which afford the desired functionalized 1,3‐dienones after ring opening.
ChemInform Abstract: Synthesis and Antipsychotic and Anticonvulsant Activity of Some New Substituted Oxa/Thiadiazolylazetidinonyl/Thiazolidinonylcarbazoles.
Authors: Kaur Hemlata , Kumar Sunil , Vishwakarma Pinki , Sharma Monica , Saxena K. K. , Kumar Ashok
Published: September 2010

The biological activity of the newly synthesized compounds (III), (V), and (VII) is evaluated.
ChemInform Abstract: Molecular Sieves as an Efficient and Recyclable Catalyst for Bromolactonization and Bromoacetoxylation Reactions.
Authors: Chen Feng , Jiang Xiaojian , Er Jun Cheng , Yeung Ying‐Yeung
Published: September 2010

A simple procedure is developed for the bromolactonization of unsaturated acids and bromoacetoxylation of olefins.
ChemInform Abstract: Nickel/Lewis Acid‐Catalyzed Carbocyanation of Alkynes Using Acetonitrile and Substituted Acetonitriles.
Authors: Yada Akira , Yukawa Tomoya , Idei Hiroaki , Nakao Yoshiaki , Hiyama Tamejiro
Published: September 2010

The scope and limitations of the carbocyanation reaction of a variety of alkynes with nitriles (I) and (V) are reported (40 examples).
ChemInform Abstract: Direct Allylation of α‐Aryl Alcohols with Allyltrimethylsilane Catalyzed by Heterogeneous Tin Ion‐Exchanged Montmorillonite.
Authors: Wang Jiacheng , Masui Yoichi , Onaka Makoto
Published: September 2010

Various secondary aryl and allylic alcohols as well as tertiary alcohol (Ib) are treated with (II) under optimized conditions to give the corresponding allyl compounds in good to excellent yields.
ChemInform Abstract: Metal Acetate/Metal Oxide in Acetic Acid: An Efficient Reagent for the Chemoselective N‐Acetylation of Amines under Green Conditions.
Authors: Brahmachari Goutam , Laskar Sujay , Sarkar Sajal
Published: September 2010

A variety of metal acetates and oxides is identified as efficient catalyst for the chemoselective N‐acetylation of amines with acetic acid as acylating agent and solvent.
ChemInform Abstract: Synthesis of Fluorinated Imines by Addition of Fluoroalkyl Radicals to Conjugated Imines.
Authors: Ueda Masafumi , Iwasada Eri , Miyata Okiko , Naito Takeaki
Published: September 2010

The radicals derived from (II) and (V) undergo generally regioselective addition to α,β‐unsaturated imines to give the β‐adducts.With oxime (IX), however, the α‐addition product is formed in low yield.
ChemInform Abstract: Synthesis of Surfactants from Furfural Derived 2[5H]‐Furanone and Fatty Amines.
Authors: Gassama Abdoulaye , Ernenwein Cedric , Hoffmann Norbert
Published: September 2010

Six novel twin‐tail amphoteric surfactants (V) and (VII) are readily prepared via a condensation reaction of furanone (I) with fatty amines (II).
ChemInform Abstract: Cyclopropyl Building Blocks for Organic Synthesis. Part 154. Convenient Access to Various 1‐Cyclopropylcyclopropane Derivatives.
Authors: de Meijere Armin , Khlebnikov Alexander F. , Suennemann Hans Wolf , Frank Daniel , Rauch Karsten , Yufit Dmitrii S.
Published: September 2010

Bicyclopropyl bromide (I) readily undergoes a bromine/lithium exchange, and the resulting lithiated cyclopropane is trapped with various electrophiles providing 1‐substituted bicyclopropyl derivatives.
ChemInform Abstract: An Efficient Procedure for Preparation of 2‐Monoalkyl or 2‐Monoaryl‐3‐ethoxycyclobutanones.
Authors: Matsuo Jun‐ichi , Okuno Ryosuke , Takeuchi Kosuke , Kawano Mizuki , Ishibashi Hiroyuki
Published: September 2010

Ketenes, generated from the corresponding acid chlorides with base, undergo [2 + 2] cycloaddition with ethyl vinyl ether to give diastereomeric mixtures of title compounds.
ChemInform Abstract: Short Synthesis of Methylenecyclopentenones by Intermolecular Pauson—Khand Reaction of Allyl Thiourea.
Authors: Petrovski Zeljko , Martins Bruno M. R. , Afonso Carlos A. M.
Published: September 2010

A novel catalytic Pauson—Khand reaction of thiourea (I) followed by thiourea elimination is presented to give very moderate yields of methylenecyclopentenones in a single step.
ChemInform Abstract: Ligand‐Controlled Selectivity in the Desymmetrization of meso Cyclopenten‐1,4‐diols via Rhodium(I)‐Catalyzed Addition of Arylboronic Acids.
Authors: Menard Frederic , Perez David , Roman Daniela Sustac , Chapman Timothy M. , Lautens Mark
Published: September 2010

Desymmetrization of cyclopenten‐1,4‐diols can be achieved via Rh‐catalyzed addition of arylboronic acids to the corresponding dicarbonate (I).
ChemInform Abstract: Palladium‐Catalyzed Allylation of Aryl Halides with Homoallyl Alcohols Bearing a Trisubstituted Double Bond: Application to Chirality Transfer from Hydroxylated Carbon to Benzylic One.
Authors: Wakabayashi Ryota , Fujino Daishi , Hayashi Sayuri , Yorimitsu Hideki , Oshima Koichiro
Published: September 2010

The method allows regio‐ and stereoselective access to allylarenes having two substituents at the 1 and 2 position of the allylic group.
ChemInform Abstract: Room‐Temperature Copper‐Catalyzed Synthesis of Primary Arylamines from Aryl Halides and Aqueous Ammonia.
Authors: Tao Chuanzhou , Liu Weiwei , Lv Aifeng , Sun Mingming , Tian Ying , Wang Qi , Zhao Jing
Published: September 2010

Due to the convenience of aqueous NH3 and the inexpensive catalyst system, the method may be of interest for application on an industrial scale.
ChemInform Abstract: Aerobic Oxidative Esterification of Alcohols Catalyzed by Polymer‐Incarcerated Gold Nanoclusters under Ambient Conditions.
Authors: Miyamura Hiroyuki , Yasukawa Tomohiro , Kobayashi Shu
Published: September 2010

The application of polymer‐incarcerated gold nanocluster catalyst for the oxidative esterification of alcohols (I) is reported.
ChemInform Abstract: Glycerol as a Cheap, Safe and Sustainable Solvent for the Catalytic and Regioselective β,β‐Diarylation of Acrylates over Palladium Nanoparticles.
Authors: Delample Mathieu , Villandier Nicolas , Douliez Jean‐Paul , Camy Severine , Condoret Jean‐Stephane , Pouilloux Yannick , Barrault Joel , Jerome Francois
Published: September 2010

Palladium nanoparticles stabilized using a cellulose‐derived aminopolysaccharide are successfully applied as catalyst in β,β‐diarylation reactions of acrylates (I) in glycerol.
ChemInform Abstract: A Facile and Efficient One‐Pot Synthesis of Polysubstituted Benzenes in Guanidinium Ionic Liquids.
Authors: Xin Xin , Wang Yan , Xu Wu , Lin Yingjie , Duan Haifeng , Dong Dewen
Published: September 2010

A variety of substituted m‐triphenyls (III) is readily prepared by reaction of chalcones (I) with malononitrile (II) in tetramethylguanidinium lactate as solvent.
ChemInform Abstract: A Novel Application of [Cr(en)2]2+ in the Synthesis of 1,2‐Diols from Aromatic Aldehydes.
Authors: Avila‐Sorrosa Alcives , Vega‐Ramirez Leticia , Rodriguez‐Dominguez Rafael , Salgado‐Zamora Hector , Peralta‐Cruz Javier , Reyes‐Arellano Alicia
Published: September 2010

A reductive pinacol type arylaldehyde (I) homocoupling process by the [Cr(en)2]2+ complex is described.
ChemInform Abstract: Synthesis of Highly Substituted 1,3‐Dienes, 1,3,5‐Trienes, and 3,6‐Disubstituted Cyclohexenes by the Palladium‐Catalyzed Coupling of Organic Halides, Internal Alkynes or 1,3‐Cyclohexadienes, and Organoboranes.
Authors: Zhang Xiaoxia , Larock Richard C.
Published: September 2010

Palladium‐catalyzed coupling of vinylic iodides with internal alkynes and organylboronic acids proceeds with excellent E‐selectivity when E‐vinylic iodides like (I) are used.
ChemInform Abstract: Platinum‐Catalyzed Intramolecular Hydroarylation of Allenyl Arenes: Efficient Synthesis of 1,4‐Dihydronaphthalenes.
Authors: Mo Juntae , Lee Phil Ho
Published: September 2010

The method allows the preparation of a broad spectrum of synthetically and biologically important title compounds under slightly modified conditions.
ChemInform Abstract: Rhodium‐Catalyzed Annulation of Ynamides with Bifunctional Arylboron Reagents.
Authors: Gourdet Benoit , Rudkin Mairi E. , Lam Hon Wei
Published: September 2010

The reaction results in formation of 2‐amidoindenes with generally good levels of regioselectivity.
ChemInform Abstract: Stereoselective Construction of Highly Functionalized Azetidines via a [2 + 2]‐Cycloaddition.
Authors: Ye Yang , Wang Hua , Fan Renhua
Published: September 2010

A one‐pot [2 + 2]‐cycloaddition of 2‐aminomalonates with chalcones via a grind‐promoted, solvent‐free Michael addition and a PhIO/Bu4NI mediated oxidative cyclization is developed.
ChemInform Abstract: 1‐Bromo‐2‐trifluoroacetylcyclobutenes as Novel Building Blocks for the Construction of Trifluoromethyl Substituted Heterocycles. Part 1. Synthesis of 5‐(Trifluoromethyl)‐2(5H)‐furanones Condensed with Substituted Cyclobutenes.
Authors: Koldobskii Andrey B. , Tsvetkov Nikolay P. , Solodova Ekaterina V. , Kalinin Valery N.
Published: September 2010

The lithiation of bromides (II) followed by carboxylation leads to acids (IV), which are readily converted into the desired lactones (V) by the action of trifluoroacetic anhydride.
ChemInform Abstract: Rhodium‐Catalyzed Synthesis of γ‐Butyrolactams and Pyrrolidines via Cycloisomerization of N‐Tethered 1,6‐Enynes.
Authors: Wang Jianping , Xie Xiaomin , Ma Fangfang , Peng Zhiyong , Zhang Lei , Zhang Zhaoguo
Published: September 2010

The title cyclization of the (Z)‐enyne amines and amides (I), (III), and (V) opens a useful access to stereodefined chloroalkylidene pyrrolidine and γ‐butyrolactam derivatives such as (II), (IV), or (VI).
ChemInform Abstract: Enantioselective Construction of Highly Substituted Pyrrolidines by Palladium‐Catalyzed Asymmetric [3 + 2] Cycloaddition of Trimethylenemethane with Ketimines.
Authors: Trost Barry M. , Silverman Steven M.
Published: September 2010

A variety of aromatic, aliphatic and cyclic imines is applied in the reaction to afford the target pyrrolidines, including spirocyclic ones, with high dia‐ and excellent enantioselectivities.
ChemInform Abstract: Tuning Electronic and Steric Effects: Highly Enantioselective [4 + 1] Pyrroline Annulation of Sulfur Ylides with α,β‐Unsaturated Imines.
Authors: Lu Liang‐Qiu , Zhang Ji‐Ji , Li Fang , Cheng Ying , An Jing , Chen Jia‐Rong , Xiao Wen‐Jing
Published: September 2010

The reaction of atropisomeric sulfur ylides (I) with unsaturated imines bearing a bulky sulfonyl group at the nitrogen provides pyrroline‐2‐carboxylates with excellent stereocontrol.
ChemInform Abstract: Indium‐Promoted Allylation Reaction of Imino‐Isatins in Aqueous Media: Synthesis of Quaternary 3‐Aminooxindoles.
Authors: Alcaide Benito , Almendros Pedro , Aragoncillo Cristina
Published: September 2010

Quaternary 3‐amino‐2‐oxindoles are obtained via allylation and propargylation reactions of imino‐isatins in aqueous media promoted by In or Zn.
ChemInform Abstract: Synthesis and Preliminary Biological Studies of 3‐Substituted Indoles Accessed by a Palladium‐Catalyzed Enantioselective Alkene Difunctionalization Reaction.
Authors: Pathak Tejas P. , Gligorich Keith M. , Welm Bryan E. , Sigman Matthew S.
Published: September 2010

Several N‐protected indoles are employed as nucleophiles in the difunctionalization reaction of ω‐hydroxyalkenyl‐substituted phenols.
ChemInform Abstract: Nucleophilic Substitution of Oxazino‐/Oxazolino‐/Benzoxazin[3,2‐b]indazoles: An Effective Route to 1H‐Indazolones.
Authors: Donald Michael B. , Conrad Wayne E. , Oakdale James S. , Butler Jeffrey D. , Haddadin Makhluf J. , Kurth Mark J.
Published: September 2010

Substrates (I), (VII), and (XIII) undergo ring‐opening with various nucleophiles to produce 1H‐indazolone products.
ChemInform Abstract: A Novel and an Efficient Catalyst for One‐Pot Synthesis of 2,4,5‐Trisubstituted Imidazoles by Using Microwave Irradiation under Solvent‐Free Conditions.
Authors: Safari Javad , Khalili Shiva Dehghan , Banitaba Sayed Hossein
Published: September 2010

An improved and rapid synthesis of trisubstituted imidazoles (III) (13 examples) by three‐component, one‐pot condensation of benzil with aryl aldehydes and NH4OAc using ammonium heptamolybdate as catalyst is developed.
ChemInform Abstract: The Acid‐Mediated Intramolecular 1,3‐Dipolar Cycloaddition of Derived 2‐Nitro‐1,1‐ethenediamines for the Synthesis of Novel Fused Bicyclic Isoxazoles.
Authors: Page Lee W. , Bailey Matthew , Beswick Paul J. , Frydrych Simon , Gleave Robert J.
Published: September 2010

The five‐membered ring‐fused compound (IIc) gives only poor yield after chromatographic work‐up.
ChemInform Abstract: Intramolecular Cascade C—S Bond Formation: Regioselective Synthesis of Substituted Benzothiazoles.
Authors: Bose D. Subhas , Idress Mohd.
Published: September 2010

Microwave‐assisted synthesis of the target compounds in diphenyl ether (or N,N‐diethylaniline) starts from readily available substrates and proceeds through formation of intermediate thiobenzanilines.
ChemInform Abstract: Synthesis and Dual PPARα/δ Agonist Effects of 1,4‐Disubstituted 1,2,3‐Triazole Analogues of GW 501516.
Authors: Ciocoiu Calin C. , Nikolic Natasa , Nguyen Huyen Hoa , Thoresen G. Hege , Aasen Arne J. , Hansen Trond Vidar
Published: September 2010

Triazole derivatives (IV) are prepared and tested for their ability to increase oleic acid oxidation in human myotubes using a high‐throughput multiwell assay.
ChemInform Abstract: Asymmetric Nazarov Reaction Catalyzed by Chiral Tris(oxazoline)/Copper(II).
Authors: Cao Peng , Deng Chao , Zhou You‐Yun , Sun Xiu‐Li , Zheng Jun‐Cheng , Xie Zuowei , Tang Yong
Published: September 2010

Alkoxy divinyl β‐ketoesters (I) undergo the title reaction to give cyclopenta[b]pyran derivatives (II) with high regio‐, diastereo‐ and enantioselectivities.
ChemInform Abstract: Synthesis of 14‐Aryl‐14H‐dibenzo[a,j]xanthenes Catalyzed by Acyclic Acidic Ionic Liquids.
Authors: Fang Dong , Liu Zu‐Liang
Published: September 2010

Some readily available, acyclic SO3‐functionalized ionic liquids are successfully used as recyclable catalysts for the synthesis of dibenzoxanthenes (III) (10 examples) via condensation of β‐naphthol with benzaldehydes.
ChemInform Abstract: Design and an Efficient Synthesis of New Thiorotenone Derivatives.
Authors: Yao Changsheng , Wang Cuihua , Jiang Bei , Feng Xiaodong , Yu Chenxia , Li Tuanjie , Tu Shujiang
Published: September 2010

A range of novel thiopyrano[3,4‐b]pyran‐5‐one derivatives (IV) and (VII) is synthesized by an effective three‐component reaction under solvent‐free and catalyst‐free conditions.
ChemInform Abstract: Inhibitors of the RET Tyrosine Kinase Based on a 2‐(Alkylsulfanyl)‐4‐(3‐thienyl) Nicotinonitrile Scaffold.
Authors: Brandt Wiebke , Mologni Luca , Preu Lutz , Lemcke Thomas , Gambacorti‐Passerini Carlo , Kunick Conrad
Published: September 2010

Structurally nicotinonitrile‐based compounds (VII) and (X) are prepared as inhibitors of the cancer‐related tyrosine kinase RET.
ChemInform Abstract: A Novel One‐Pot Synthesis of Substituted Quinolines.
Authors: Sabbaghan Maryam , Yavari Issa , Hossaini Zinatossadat , Souri Sanaz
Published: September 2010

In the presence of ethyl bromopyruvate (III), reaction of isatin (I) and acetylenedicarboxylates (II) results in formation of quinolines (IV) bearing the ethyl ester group in the 4‐position.
ChemInform Abstract: Optimization of 7‐Alkene‐3‐quinolinecarbonitriles as Src Kinase Inhibitors.
Authors: Boschelli Diane H. , Wang Daniel , Wang Yan , Wu Biqi , Honores Erick E. , Sosa Ana Carolina Barrios , Chaudhary Inder , Golas Jennifer , Lucas Judy , Boschelli Frank
Published: September 2010

The preparation of a series of potent Src kinase inhibitors (I) is reported.
ChemInform Abstract: Design and Preparation of Aza‐Analogues of Benzo[c]phenanthridine Framework with Cytotoxic and Antiplasmodial Activities.
Authors: Yapi Ange‐Desire , Desbois Nicolas , Chezal Jean‐Michel , Chavignon Olivier , Teulade Jean‐Claude , Valentin Alexis , Blache Yves
Published: September 2010

A regioselective Heck coupling is used as key reaction for the synthesis of novel benzophenanthridine‐like compounds such as (II), (IV) or (V).
ChemInform Abstract: An Efficient Synthesis of Thiazolo[3,2‐a]pyrimidinones.
Authors: Ahmad Nadia M. , Jones Keith
Published: September 2010

The short approach includes condensation of 2‐aminothiazoles with diesters (II) followed by cyclization in the presence of commercially available Eaton′s reagent.
ChemInform Abstract: AlCl3‐Induced (Hetero)arylation of Thienopyrimidine Ring: A New Synthesis of 4‐Substituted Thieno[2,3‐d]pyrimidines.
Authors: Kumar K. Shiva , Chamakuri Srinivas , Vishweshwar Peddy , Iqbal Javed , Pal Manojit
Published: September 2010

as potential bioactive substances
ChemInform Abstract: New Quinoxaline 1,4‐Di‐N‐oxides: Anticancer and Hypoxia‐Selective Therapeutic Agents.
Authors: Ismail Magda M. F. , Amin Kamelia M. , Noaman Eman , Soliman Dalia H. , Ammar Yousry A.
Published: September 2010

A series of novel quinoxaline 1,4‐di‐N‐oxides is prepared and evaluated for antitumor and hypoxia‐selective cytotoxic activities.
ChemInform Abstract: Synthesis of Novel 6,6a,7,8‐Tetrahydro‐5H‐naphtho[1,2‐e]pyrimido[4,5‐b][1,4]diazepines under Microwave Irradiation as Potential Antitumor Agents.
Authors: Insuasty Braulio , Garcia Angelica , Quiroga Jairo , Abonia Rodrigo , Nogueras Manuel , Cobo Justo
Published: September 2010

Chemical synthesis and antitumor activity are described.
ChemInform Abstract: Palladium‐Mediated Reductive Mizoroki—Heck Cyclization Strategy for the Regioselective Formation of Dibenzoazocinone Framework.
Authors: Majumdar K. C. , Ghosh Tapas , Chakravorty Santanu
Published: September 2010

Optimized conditions provide the title compounds (II) and (IV) as potential biologically active frameworks.
ChemInform Abstract: Design, Synthesis and SAR of Phenylamino‐Substituted 5,11‐Dihydrodibenzo[a,d]cyclohepten‐10‐ones and 11H‐Dibenzo[b,f]oxepin‐10‐ones as p38 MAP Kinase Inhibitors.
Authors: Dorn Angelika , Schattel Verena , Laufer Stefan
Published: September 2010

A series of 28 title compounds of type (III) and (V) is prepared as p38 MAP kinase inhibitors.
ChemInform Abstract: Copper Catalyzed Asymmetric Propargylation of Aldehydes.
Authors: Fandrick Daniel R. , et al. et al.
Published: September 2010

The highly enantio‐ and regioselective copper catalyzed propargylation of aldehydes using a propargyl borolane reagent is reported.
ChemInform Abstract: Modular Synthesis of Polybenzo[b]silole Compounds for Hole‐Blocking Material in Phosphorescent Organic Light Emitting Diodes.
Authors: Ilies Laurean , Sato Yoshiharu , Mitsui Chikahiko , Tsuji Hayato , Nakamura Eiichi
Published: September 2010

A series of conjugated molecules containing multiple benzosilole units are synthesized and utilized as efficient hole‐blocking materials for phosphorescent OLEDs.
ChemInform Abstract: Iron‐Catalyzed, Directed Oxidative Arylation of Olefins with Organozinc and Grignard Reagents.
Authors: Ilies Laurean , Okabe Jun , Yoshikai Naohiko , Nakamura Eiichi
Published: September 2010

The reaction is catalyzed by Fe(acac)3 mostly without any ligand.
ChemInform Abstract: Studies on New Phytochemicals. Part 72. New Diterpenoids from Caesalpinia Species and Their Cytotoxic Activity
Authors: Das Biswananth , Srinivas Yallamalla , Sudhakar Chithaluri , Mahender Ibram , Laxminarayana Keetha , Reddy Parigi Raghavendar , Raju Tuniki Venugopal , Jakka Naga Mahesh , Rao Janapala Venkateswara
Published: September 2010

isolation, structure elucidation and cytotoxicity
ChemInform Abstract: The Use of Ultrastable Y Zeolites in the Ferrier Rearrangement of Acetylated and Benzylated Glycals.
Authors: Levecque Pieter , Gammon David W. , Jacob Pierre , De Vos Dirk , Sels Bert
Published: September 2010

Zeolite CBV‐720 is an efficient catalyst for the Ferrier rearrangement of glycals (I) with a variety of nucleophiles.
ChemInform Abstract: Synthesis of gem‐Difluoromethylenated Analogues of Anamarine.
Authors: Lin Jing , Qiu Xiao‐Long , Qing Feng‐Ling
Published: September 2010

A novel difluorinated anamarine derivative (IX) is prepared via indium mediated difluoropropargylation of aldehyde, obtained by oxidation of alcohol (II), and TEMPO‐catalyzed oxidative cyclization of diol (VI) as key steps.
ChemInform Abstract: Oxytrofalcatins A (Ia)—F (IV), N‐Benzoylindole Analogues from the Roots of Oxytropis falcata (Leguminosae).
Authors: Chen Wen‐Hao , Wu Quan‐Xiang , Wang Rui , Shi Yan‐Ping
Published: September 2010

Prelimnary in vitro tests for cytotoxicity reveal that all components are inactive.
ChemInform Abstract: Bisnicalaterines B and C, Atropisomeric Bisindole Alkaloids from Hunteria zeylanica, Showing Vasorelaxant Activity.
Authors: Morita Hiroshi , et al. et al.
Published: September 2010

The structures of bisnicalaterines B (I) and its atropisomer are determined by spectroscopic means and computational methods.
ChemInform Abstract: Total Synthesis of (+)‐Sieboldine A.
Authors: Canham Stephen M. , France David J. , Overman Larry E.
Published: September 2010

The synthesis is accomplished in 20 steps starting from an enantiomerically pure furanone.
ChemInform Abstract: Total Synthesis of Enantiopure Phalarine via a Stereospecific Pictet—Spengler Reaction: Traceless Transfer of Chirality from L‐Tryptophan.
Authors: Trzupek John D. , Lee Dongjoo , Crowley Brendan M. , Marathias Vasilios M. , Danishefsky Samuel J.
Published: September 2010

The total synthesis of (V) is achieved with the construction of the intermediate (IV) with complete diastereoselectivity as a key step.
ChemInform Abstract: Synthesis and Glycosidase Inhibition of the Enantiomer of (‐)‐Steviamine, the First Example of a New Class of Indolizidine Alkaloid.
Authors: Hu Xiang‐Guo , Batholomew Barbara , Nash Robert J. , Wilson Francis X. , Fleet George W. J. , Nakagawa Shinpei , Kato Atsushi , Jia Yue‐Mei , van Well Renate , Yu Chu‐Yi
Published: September 2010

Weak inhibitory activity is found for (+)‐I, its C‐5 epimer and natural (‐)‐(I).
ChemInform Abstract: Design, Synthesis and Antiproliferative Activity of Styryl Lactones Related to (+)‐Goniofufurone.
Authors: Popsavin Velimir , Sreco Bojana , Benedekovic Goran , Francuz Jovana , Popsavin Mirjana , Kojic Vesna , Bogdanovic Gordana
Published: September 2010

The synthesis of (+)‐goniofufurone‐related compounds (III), (IX), (XI), and (XII) is described.
ChemInform Abstract: Novel Bisstyryl Derivatives of Bakuchiol: Targeting Oral Cavity Pathogens.
Authors: Reddy Mallepally V. , Thota Niranjan , Sangwan Payare L. , Malhotra Pankaj , Ali Furqan , Khan Inshad A. , Chimni Swapandeep S. , Koul Surrinder
Published: September 2010

Bakuchiol derivatives (III), (VI), and (VIII) are obtained via Heck and oxidative Heck coupling reaction, respectively.
ChemInform Abstract: Synthesis and Biological Evaluation of a Novel Series of 2,2‐Bisaminomethylated Aurone Analogues as Antiinflammatory and Antimicrobial Agents.
Authors: Bandgar Babasaheb P. , Patil Sachin A. , Korbad Balaji L. , Biradar Satish C. , Nile Shivraj N. , Khobragade Chandrahasya N.
Published: September 2010

The 2,2‐bisaminomethylated aurone analogues (IV) are obtained for the first time.
ChemInform Abstract: Formal Synthesis of (‐)‐Neopeltolide Featuring a Highly Stereoselective Oxocarbenium Formation/Reduction Sequence.
Authors: Martinez‐Solorio Dionicio , Jennings Michael P.
Published: September 2010

The synthesis of macrolactone (IV) as precursor of unnatural neopeltolide is achieved via allylation of lactone (I) and subsequent stereoselective reduction of an oxocarbenium compound, generated in situ.
ChemInform Abstract: Synthesis and Biological Activity of 2‐(Trifluoromethyl)‐1H‐benzimidazole Derivatives Against Some Protozoa and Trichinella spiralis.
Authors: Hernandez‐Luis Francisco , Hernandez‐Campos Alicia , Castillo Rafael , Navarrete‐Vazquez Gabriel , Soria‐Arteche Olivia , Hernandez‐Hernandez Manuel , Yepez‐Mulia Lilian
Published: September 2010

Title compounds (I) are evaluated in vitro against various protozoan parasites (Giardia intestinalis, Entamoeba histolytica, Trichomonas vaginalis, Leishmania mexicana) and the nematode Trichinella spiralis.