bluuebunny/crossref_metadata_2025 huggingface dataset:
Hygrothermal Dynamic and Mould Growth Risk Predictions for Concrete Tiles by Using Least Squares Support Vector Machines
Authors: Freire Roberto Zanetti , Santos Gerson Henrique dos , Coelho Leandro dos Santos
Published: July 2017

The hygrothermal analysis of roofs is relevant due to the large areas exposed to a wide range of weather conditions, these directly affecting the energy performance and thermal comfort of buildings. However, after a long life service, the solar absorptivity coatings of roofs can be altered by mould accumulation. Based on two well established mathematical models, one that adopts driving potentials to calculate temperature, moist air pressure and water vapor pressure gradients, and the other to estimate the mould growth risk on surfaces, this research introduces an approach to predict mould growth considering a reduced computational effort and simulation time. By adopting multiple MISO (Multiple-Input, Single-Output) Nonlinear AutoRegressive with eXogenous inputs (NARX) models, a machine learning technique known as Least Squares Support Vector Machines (LS-SVM), a maximum margin model based on structural risk minimization, was used to predict vapor flux, sensible heat flux, latent heat flux, and mould growth risk on roof surfaces. The proposed model was validated in terms of the Multiple Correlation Coefficient (R2R2R2), Mean Square Error (MSE) and Mean Absolute Error (MAE) performance indices considering as input the weather file from Curitiba city—Brazil, showing consistent precision when compared to the results of a validated numerical model.
Real-Time Distributed Economic Model Predictive Control for Complete Vehicle Energy Management
Authors: Romijn Constantijn , Donkers Tijs , Kessels John , Weiland Siep
Published: July 2017

In this paper, a real-time distributed economic model predictive control approach for complete vehicle energy management (CVEM) is presented using a receding control horizon in combination with a dual decomposition. The dual decomposition allows the CVEM optimization problem to be solved by solving several smaller optimization problems. The receding horizon control problem is formulated with variable sample intervals, allowing for large prediction horizons with only a limited number of decision variables and constraints in the optimization problem. Furthermore, a novel on/off control concept for the control of the refrigerated semi-trailer, the air supply system and the climate control system is introduced. Simulation results on a low-fidelity vehicle model show that close to optimal fuel reduction performance can be achieved. The fuel reduction for the on/off controlled subsystems strongly depends on the number of switches allowed. By allowing up to 15-times more switches, a fuel reduction of 1.3% can be achieved. The approach is also validated on a high-fidelity vehicle model, for which the road slope is predicted by an e-horizon sensor, leading to a prediction of the propulsion power and engine speed. The prediction algorithm is demonstrated with measured ADASIS information on a public road around Eindhoven, which shows that accurate prediction of the propulsion power and engine speed is feasible when the vehicle follows the most probable path. A fuel reduction of up to 0.63% is achieved for the high-fidelity vehicle model.
Effects of Environmental Changes on the Occurrence of Oreomunnea mexicana (Juglandaceae) in a Biodiversity Hotspot Cloud Forest
Authors: Alfonso-Corrado Cecilia , Naranjo-Luna Francisco , Clark-Tapia Ricardo , Campos Jorge , Rojas-Soto Octavio , Luna-Krauletz María , Bodenhorn Barbara , Gorgonio-Ramírez Montserrat , Pacheco-Cruz Nelly
Published: July 2017

The tropical montane cloud forests are recognized as one of the most biodiverse ecosystems. In spite of this, they are among the most threatened ecosystems in the world. This study integrates three ecological approaches generally studied separately: climate change scenery, ecological niche and population dynamics of Oreomunnea mexicana (an endangered and relict species), to understand how environmental change affects the population structure in the cloud forest that will allow its conservation. Potential distribution under future climatic scenarios of the species at national and regional levels was generated from the Maxent algorithm. Also, the current abundance, distribution and the ecological niche of the species were analyzed at the regional level. Changes in potential distribution under two climatic models suggest a habitat reduction from 36% to 55% nationally, and 2% to 9% at a regional level, for 2050 and 2070, respectively. The current distribution of the species is fragmented and consists of subpopulations that have spatial structures of aggregated populations and a size structure in reversed “J” form. The ecological niche of the species is highly specialized and sensitive to environmental changes. O. mexicana is a flagship species of biological and cultural importance to the region’s inhabitants and could be fundamental to the conservation of tropical montane cloud forests.
The Effect of Astaxanthin-Rich Microalgae “Haematococcus pluvialis” and Wholemeal Flours Incorporation in Improving the Physical and Functional Properties of Cookies
Authors: Hossain A. K. M. Mofasser , Brennan Margaret A. , Mason Susan L. , Guo Xinbo , Zeng Xin An , Brennan Charles S.
Published: July 2017

Marine-based food supplements can improve human nutrition. In an effort to modulate glycaemic response and enhance nutritional aspects, marine-derived algal food rich in astaxanthin was used in the formulation of a model food (wholemeal cookie). Astaxanthin substitution of cookies made from three flours (wheat, barley and oat) demonstrated a significant reduction in the rate of glucose released during in vitro digestion together with an increase in the total phenolic content (TPC) and antioxidant capacity of the food. The significantly (p < 0.005) lower free glucose release was observed from cookies with 15% astaxanthin, followed by 10% and then 5% astaxanthin in comparison with control cookies of each flour. Total phenolic content, DPPH radical scavenging and Oxygen Radical Absorbance Capacity (ORAC) value also notably increased with increase in astaxanthin content. The results evidence the potential use of microalgae to enhance the bioactive compounds and lower the glycaemic response of wholemeal flour cookie.
Multimethod Approach to the Study of Recent Volcanic Ashes from Tengger Volcanic Complex, Eastern Java, Indonesia
Authors: Santoso Nono Agus , Bijaksana Satria , Kodama Kazuto , Santoso Djoko , Dahrin Darharta
Published: July 2017

Volcanic ash is a volcanic product with a wide distribution that can be used as a geological marker. In volcanic regions such as Indonesia, the identification of the sources of volcanic ash and tuff layers from different volcanoes or eruptive events is a challenging task. In this study, samples of volcanic ash from the 2010 eruption of Bromo—a relatively young and active tuff cone volcano within the Sandsea caldera in the Tengger volcanic complex in East Java, Indonesia—along with two older tuff layers from the same caldera (Widodaren tuff: 1.8 kyr and Segarawedi tuff: 33 kyr) were subjected to magnetic measurements, geochemical analyses, and petrographic analyses. The aim is to attempt to use magnetic characters as a fingerprint for volcanic ash and tuff layers. The results show that the samples had variations in grain size and magnetic domain as indicated by the hysteresis parameters. These magnetic characters correlated with the results of geochemical and petrographic analyses, suggesting that magnetic properties may potentially be used as fingerprints to identify volcanic ashes and tuff layers.
Clinical Outcomes and Co-Occurring Mutations in Patients with RUNX1-Mutated Acute Myeloid Leukemia
Authors: Khan Maliha , Cortes Jorge , Kadia Tapan , Naqvi Kiran , Brandt Mark , Pierce Sherry , Patel Keyur , Borthakur Gautam , Ravandi Farhad , Konopleva Marina , Kornblau Steven , Kantarjian Hagop , Bhalla Kapil , DiNardo Courtney
Published: July 2017

(1) Runt-related transcription factor 1 (RUNX1) mutations in acute myeloid leukemia (AML) are often associated with worse prognosis. We assessed co-occurring mutations, response to therapy, and clinical outcomes in patients with and without mutant RUNX1 (mRUNX1); (2) We analyzed 328 AML patients, including 177 patients younger than 65 years who received intensive chemotherapy and 151 patients >65 years who received hypomethylating agents. RUNX1 and co-existing mutations were identified using next-generation sequencing; (3) RUNX1 mutations were identified in 5.1% of younger patients and 15.9% of older patients, and were significantly associated with increasing age (p = 0.01) as well as intermediate-risk cytogenetics including normal karyotype (p = 0.02) in the elderly cohort, and with lower lactate dehydrogenase (LDH; p = 0.02) and higher platelet count (p = 0.012) overall. Identified co-occurring mutations were primarily ASXL1 mutations in older patients and RAS mutations in younger patients; FLT3-ITD and IDH1/2 co-mutations were also frequent. Younger mRUNX1 AML patients treated with intensive chemotherapy experienced inferior treatment outcomes. In older patients with AML treated with hypomethylating agent (HMA) therapy, response and survival was independent of RUNX1 status. Older mRUNX1 patients with prior myelodysplastic syndrome or myeloproliferative neoplasms (MDS/MPN) had particularly dismal outcome. Future studies should focus on the prognostic implications of RUNX1 mutations relative to other co-occurring mutations, and the potential role of hypomethylating agents for this molecularly-defined group.
Potential Role of Microtubule Stabilizing Agents in Neurodevelopmental Disorders
Authors: Bonini Sara Anna , Mastinu Andrea , Ferrari-Toninelli Giulia , Memo Maurizio
Published: July 2017

Neurodevelopmental disorders (NDDs) are characterized by neuroanatomical abnormalities indicative of corticogenesis disturbances. At the basis of NDDs cortical abnormalities, the principal developmental processes involved are cellular proliferation, migration and differentiation. NDDs are also considered “synaptic disorders” since accumulating evidence suggests that NDDs are developmental brain misconnection syndromes characterized by altered connectivity in local circuits and between brain regions. Microtubules and microtubule-associated proteins play a fundamental role in the regulation of basic neurodevelopmental processes, such as neuronal polarization and migration, neuronal branching and synaptogenesis. Here, the role of microtubule dynamics will be elucidated in regulating several neurodevelopmental steps. Furthermore, the correlation between abnormalities in microtubule dynamics and some NDDs will be described. Finally, we will discuss the potential use of microtubule stabilizing agents as a new pharmacological intervention for NDDs treatment.
Sulfur Protects Pakchoi (Brassica chinensis L.) Seedlings against Cadmium Stress by Regulating Ascorbate-Glutathione Metabolism
Authors: Lou Lili , Kang Jingquan , Pang Hongxi , Li Qiuyu , Du Xiaoping , Wu Wei , Chen Junxiu , Lv Jinyin
Published: July 2017

Cadmium (Cd) pollution in food chains pose a potential health risk for humans. Sulfur (S) is a significant macronutrient that plays a significant role in the regulation of plant responses to diverse biotic and abiotic stresses. However, no information is currently available about the impact of S application on ascorbate-glutathione metabolism (ASA-GSH cycle) of Pakchoi plants under Cd stress. The two previously identified genotypes, namely, Aikangqing (a Cd-tolerant cultivar) and Qibaoqing (a Cd-sensitive cultivar), were utilized to investigate the role of S to mitigate Cd toxicity in Pakchoi plants under different Cd regimes. Results showed that Cd stress inhibited plant growth and induced oxidative stress. Exogenous application of S significantly increased the tolerance of Pakchoi seedlings suffering from Cd stress. This effect was demonstrated by increased growth parameters; stimulated activities of the antioxidant enzymes and upregulated genes involved in the ASA-GSH cycle and S assimilation; and by the enhanced ASA, GSH, phytochelatins, and nonprotein thiol production. This study shows that applying S nutrition can mitigate Cd toxicity in Pakchoi plants which has the potential in assisting the development of breeding strategies aimed at limiting Cd phytoaccumulation and decreasing Cd hazards in the food chain.
The Positive Correlation of the Enhanced Immune Response to PCV2 Subunit Vaccine by Conjugation of Chitosan Oligosaccharide with the Deacetylation Degree
Authors: Zhang Guiqiang , Cheng Gong , Jia Peiyuan , Jiao Siming , Feng Cui , Hu Tao , Liu Hongtao , Du Yuguang
Published: July 2017

Chitosan oligosaccharides (COS), the degraded products of chitosan, have been demonstrated to have versatile biological functions. In primary studies, it has displayed significant adjuvant effects when mixed with other vaccines. In this study, chitosan oligosaccharides with different deacetylation degrees were prepared and conjugated to porcine circovirus type 2 (PCV2) subunit vaccine to enhance its immunogenicity. The vaccine conjugates were designed by the covalent linkage of COSs to PCV2 molecules and administered to BALB/c mice three times at two-week intervals. The results indicate that, as compared to the PCV2 group, COS–PCV2 conjugates remarkably enhanced both humoral and cellular immunity against PCV2 by promoting lymphocyte proliferation and initiating a mixed T-helper 1 (Th1)/T-helper 2 (Th2) response, including raised levels of PCV2-specific antibodies and an increased production of inflammatory cytokines. Noticeably, with the increasing deacetylation degree, the stronger immune responses to PCV2 were observed in the groups with COS-PCV2 vaccination. In comparison with NACOS (chitin oligosaccharides)–PCV2 and LCOS (chitosan oligosaccharides with low deacetylation degree)–PCV2, HCOS (chitosan oligosaccharides with high deacetylation degree)–PCV2 showed the highest adjuvant effect, even comparable to that of PCV2/ISA206 (a commercialized adjuvant) group. In summary, COS conjugation might be a viable strategy to enhance the immune response to PCV2 subunit vaccine, and the adjuvant effect was positively correlated with the deacetylation degree of COS.
Protective Effects of Six Selected Dietary Compounds against Leptin-Induced Proliferation of Oestrogen Receptor Positive (MCF-7) Breast Cancer Cells
Authors: Ediriweera Meran Keshawa , Tennekoon Kamani Hemamala , Samarakoon Sameera Ranganath , Thabrew Ira , De Silva E. Dilip
Published: July 2017

Abstract: Background: Obesity is considered as one of the risk factors for breast cancer. Leptin has been found to be involved in breast cancer progression. Therefore, novel approaches to antagonize biological effects of leptin are much needed. The objective of this study was to evaluate the protective effects of six dietary compounds (quercetin, curcumin, gallic acid, epigallocatechin gallate (EGCG), ascorbic acid and catechin) and assess the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) in leptin-stimulated MCF-7 breast cancer cells in vitro. Methods: MCF-7 cells were exposed to leptin, leptin and compound and compound alone for 48 h. Cell viability was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MTT and fluorometric assays after 48 h incubation. Phosphorylation of ERK1/2 was quantified by ELISA. Results: Only quercetin, curcumin and EGCG showed significant protective effects against leptin-induced proliferation of MCF-7 cells. Increase in ERK1/2 phosphorylation in response to leptin was reduced by the addition of quercetin, curcumin and EGCG. Conclusions: Considering the high prevalence of obesity, this observation provides a rationale for use of curcumin, quercetin and EGCG as antagonists of leptin in the treatment of obese breast cancer patients.
Rapid Quantification of Major Volatile Metabolites in Fermented Food and Beverages Using Gas Chromatography-Mass Spectrometry
Authors: Pinu Farhana , Villas-boas Silas G.
Published: July 2017

Here we present a method for the accurate quantification of major volatile metabolites found in different food and beverages, including ethanol, acetic acid and other aroma compounds, using gas chromatography coupled to mass spectrometry (GC-MS). The method is combined with a simple sample preparation procedure using sodium chloride and anhydrous ethyl acetate. The GC-MS analysis was accomplished within 4.75 min, and over 80 features were detected, of which 40 were positively identified using an in-house and a commercialmass spectrometry (MS) library. We determined different analytical parameters of these metabolites including the limit of detection (LOD), limit of quantitation (LOQ) and range of quantification. In order to validate the method, we also determined detailed analytical characteristics of five major fermentation end products including ethanol, acetic acid, isoamyl alcohol, ethyl-L-lactate and, acetoin. The method showed very low technical variability for the measurements of these metabolites in different matrices (<3%) with an excellent accuracy (100% ± 5%), recovery (100% ± 10%), reproducibility and repeatability [Coefficient of variation (CV) 1–10%)]. To demonstrate the applicability of the method, we analysed different fermented products including balsamic vinegars, sourdough, distilled (whisky) and non-distilled beverages (wine and beer).
Inoculation with Azospirillum sp. and Herbaspirillum sp. Bacteria Increases the Tolerance of Maize to Drought Stress
Authors: Curá José , Franz Diego , Filosofía Julián , Balestrasse Karina , Burgueño Lautaro
Published: July 2017

Stress drought is an important abiotic factor that leads to immense losses in crop yields around the world. Strategies are urgently needed to help plants adapt to drought in order to mitigate crop losses. Here we investigated the bioprotective effects of inoculating corn grown under drought conditions with two types of plant growth-promoting rhizobacteria (PGPR), A. brasilense, strain SP-7, and H. seropedicae, strain Z-152. Plants inoculated with the bacteria were grown in a greenhouse with perlite as a substrate. Two hydric conditions were tested: normal well-watered conditions and drought conditions. Compared to control non-inoculated plants, those that were inoculated with PGPR bacteria showed a higher tolerance to the negative effects of water stress in drought conditions, with higher biomass production; higher carbon, nitrogen, and chlorophyll levels; and lower levels of abscisic acid and ethylene, which are plant hormones that affect the stress response. The oxidative stress levels of these plants were similar to those of non-inoculated plants grown in well-watered conditions, showing fewer injuries to the cell membrane. We also noted higher relative water content in the vegetal tissue and better osmoregulation in drought conditions in inoculated plants, as reflected by significantly lower proline content. Finally, we observed lower gene expression of ZmVP14 in the inoculated plants; notably, ZmVP14 is involved in the biosynthesis of abscisic acid. Taken together, these results demonstrate that these bacteria could be used to help plants cope with the negative effects of drought stress conditions.
Rapid Mechanistic Evaluation and Parameter Estimation of Putative Inhibitors in a Single-Step Progress-Curve Analysis: The Case of Horse Butyrylcholinesterase
Authors: Stojan Jure
Published: July 2017

Highly efficient and rapid lead compound evaluation for estimation of inhibition parameters and type of inhibition is proposed. This is based on a single progress-curve measurement in the presence of each candidate compound, followed by the simultaneous analysis of all of these curves using the ENZO enzyme kinetics suite, which can be implemented as a web application. In the first step, all of the candidate ligands are tested as competitive inhibitors. Where the theoretical curves do not correspond to the experimental data, minimal additional measurements are added, with subsequent processing according to modified reaction mechanisms.
A Novel Fluoroimmunoassay for Detecting Ruscogenin with Monoclonal Antibodies Conjugated with CdSe/ZnS Quantum Dots
Authors: Zhang Hongwei , Xu Tao , Gao Lan , Liu Xiufeng , Liu Jihua , Yu Boyang
Published: July 2017

Ruscogenin (RUS) is a steroidal sapogenin found in Ruscus aculeatus and Ophiopogon japonicus with several pharmacological activities. In the work reported herein, a novel method termed competitive fluorescence-linked immunosorbent assay (cFLISA) based on monoclonal antibodies (mAbs) coupled with quantum dots (QDs) was developed for the quick and sensitive determination of RUS in biological samples. The mAbs against RUS were conjugated with CdSe/ZnS QDs by the crossing-linking reagents and an indirect cFLISA method was developed. There was a good linear relationship between inhibition efficiency and logarithm concentration of RUS which was varied from 0.1 to 1000 ng/mL. The IC50 and limit of detection (LOD) were 9.59 ng/mL and 0.016 ng/mL respectively, which much lower than the enzyme-linked immunosorbent assay (ELISA) method. The recoveries in plasma and tissues were ranged from 82.3% to 107.0% and the intra- and inter-day precision values were below 15%. The developed cFLISA has been successfully applied to the measurement of the concentrations of RUS in biological samples of rats, and showed great potential for the tissue distribution study of RUS. The cFLISA method may provide a valuable tool for the analysis of small molecules in biological samples and such an approach could be applied to other natural products.
Synthesis, Characterization and In Vitro Evaluation of a Novel Glycol Chitosan-EDTA Conjugate to Inhibit Aminopeptidase-Mediated Degradation of Thymopoietin Oligopeptides
Authors: Feng Jiao , Chen Yan , Li Feng , Cui Lili , Shi Nianqiu , Kong Wei , Zhang Yong
Published: July 2017

In this study, a novel conjugate consisting of glycol chitosan (GCS) and ethylene diamine tetraacetic acid (EDTA) was synthesized and characterized in terms of conjugation and heavy metal ion chelating capacity. Moreover, its potential application as a metalloenzyme inhibitor was evaluated with three thymopoietin oligopeptides in the presence of leucine aminopeptidase. The results from FTIR and NMR spectra revealed that the covalent attachment of EDTA to GCS was achieved by the formation of amide bonds between the carboxylic acid group of EDTA and amino groups of GCS. The conjugated EDTA lost part of its chelating capacity to cobalt ions compared with free EDTA as evidenced by the results of cobalt ion chelation-mediated fluorescence recovery of calcein. However, further investigation confirmed that GCS-EDTA at low concentrations significantly inhibited leucine aminopeptidase-mediated degradation of all thymopoietin oligopeptides.
Lactic Acid Bacteria and Their Bacteriocins: Classification, Biosynthesis and Applications against Uropathogens: A Mini-Review
Authors: Mokoena Mduduzi Paul
Published: July 2017

Several lactic acid bacteria (LAB) isolates from the Lactobacillus genera have been applied in food preservation, partly due to their antimicrobial properties. Their application in the control of human pathogens holds promise provided appropriate strains are scientifically chosen and a suitable mode of delivery is utilized. Urinary tract infection (UTI) is a global problem, affecting mainly diabetic patients and women. Many uropathogens are developing resistance to commonly used antibiotics. There is a need for more research on the ability of LAB to inhibit uropathogens, with a view to apply them in clinical settings, while adhering to strict selection guidelines in the choice of candidate LAB. While several studies have indicated the ability of LAB to elicit inhibitory activities against uropathogens in vitro, more in vivo and clinical trials are essential to validate the efficacy of LAB in the treatment and prevention of UTI. The emerging applications of LAB such as in adjuvant therapy, oral vaccine development, and as purveyors of bioprotective agents, are relevant in infection prevention and amelioration. Therefore, this review explores the potential of LAB isolates and their bacteriocins to control uropathogens, with a view to limit clinical use of antibiotics.
Flexible Carbon Nanotube Modified Separator for High-Performance Lithium-Sulfur Batteries
Authors: Liu Bin , Wu Xiaomeng , Wang Shan , Tang Zhen , Yang Quanling , Hu Guo-Hua , Xiong Chuanxi
Published: July 2017

Lithium-sulfur (Li-S) batteries have become promising candidates for electrical energy storage systems due to their high theoretical specific energy density, low cost and environmental friendliness. However, there are some technical obstacles of lithium-sulfur batteries to be addressed, such as the shuttle effect of polysulfides. Here, we introduced organically modified carbon nanotubes (CNTs) as a coating layer for the separator to optimize structure and enhance the performance of the Li-S battery. The results showed that the cell with a CNTs-coated separator exhibited an excellent cycling performance. Compared to the blank separator, the initial discharge capacity and the capacity after 100 cycles for the CNTs-coated separator was increased by 115% and 161%, respectively. Besides, according to the rate capability test cycling from 0.1C to 2C, the battery with a CNTs-coated separator still released a capacity amounting to 90.2% of the initial capacity, when the current density returned back to 0.1C. It is believed that the organically modified CNTs coating effectively suppresses the shuttle effect during the cycling. The employment of a CNTs-coated separator provides a promising approach for high-performance lithium-sulfur batteries.
The Bioactivity and Photocatalytic Properties of Titania Nanotube Coatings Produced with the Use of the Low-Potential Anodization of Ti6Al4V Alloy Surface
Authors: Radtke Aleksandra , Topolski Adrian , Jędrzejewski Tomasz , Kozak Wiesław , Sadowska Beata , Więckowska-Szakiel Marzena , Szubka Magdalena , Talik Ewa , Pleth Nielsen Lars , Piszczek Piotr
Published: July 2017

Titania nanotube (TNT) coatings were produced using low-potential anodic oxidation of Ti6Al4V substrates in the potential range 3–20 V. They were analysed by X-ray diffraction (XRD), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). The wettability was estimated by measuring the contact angle when applying water droplets. The bioactivity of the TNT coatings was established on the basis of the biointegration assay (L929 murine fibroblasts adhesion and proliferation) and antibacterial tests against Staphylococcus aureus (ATCC 29213). The photocatalytic efficiency of the TNT films was studied by the degradation of methylene blue under UV irradiation. Among the studied coatings, the TiO2 nanotubes obtained with the use of 5 V potential (TNT5) were found to be the most appropriate for medical applications. The TNT5 sample possessed antibiofilm properties without enriching it by additional antimicrobial agent. Furthermore, it was characterized by optimal biocompatibility, performing better than pure Ti6Al4V alloy. Moreover, the same sample was the most photocatalytically active and exhibited the potential for the sterilization of implants with the use of UV light and for other environmental applications.
Electrostatic Spray Deposition-Based Manganese Oxide Films—From Pseudocapacitive Charge Storage Materials to Three-Dimensional Microelectrode Integrands
Authors: Agrawal Richa , Adelowo Ebenezer , Baboukani Amin , Villegas Michael , Henriques Alexandra , Wang Chunlei
Published: July 2017

In this study, porous manganese oxide (MnOx) thin films were synthesized via electrostatic spray deposition (ESD) and evaluated as pseudocapacitive electrode materials in neutral aqueous media. Very interestingly, the gravimetric specific capacitance of the ESD-based electrodes underwent a marked enhancement upon electrochemical cycling, from 72 F∙g−1 to 225 F∙g−1, with a concomitant improvement in kinetics and conductivity. The change in capacitance and resistivity is attributed to a partial electrochemical phase transformation from the spinel-type hausmannite Mn3O4 to the conducting layered birnessite MnO2. Furthermore, the films were able to retain 88.4% of the maximal capacitance after 1000 cycles. Upon verifying the viability of the manganese oxide films for pseudocapacitive applications, the thin films were integrated onto carbon micro-pillars created via carbon microelectromechanical systems (C-MEMS) for examining their application as potential microelectrode candidates. In a symmetric two-electrode cell setup, the MnOx/C-MEMS microelectrodes were able to deliver specific capacitances as high as 0.055 F∙cm−2 and stack capacitances as high as 7.4 F·cm−3, with maximal stack energy and power densities of 0.51 mWh·cm−3 and 28.3 mW·cm−3, respectively. The excellent areal capacitance of the MnOx-MEs is attributed to the pseudocapacitive MnOx as well as the three-dimensional architectural framework provided by the carbon micro-pillars.
Iodine Intake through Processed Food: Case Studies from Egypt, Indonesia, the Philippines, the Russian Federation and Ukraine, 2010–2015
Authors: Knowles Jacky , Van der Haar Frits , Shehata Magdy , Gerasimov Gregory , Bimo Bimo , Cavenagh Bettina , Maramag Cherry , Otico Edward , Izwardy Doddy , Spohrer Rebecca , Garrett Greg
Published: July 2017

The current performance indicator for universal salt iodisation (USI) is the percentage of households using adequately iodised salt. However, the proportion of dietary salt from household salt is decreasing with the increase in consumption of processed foods and condiments globally. This paper reports on case studies supported by the Global Alliance for Improved Nutrition (GAIN)-UNICEF USI Partnership Project to investigate processed food industry use of adequately iodised salt in contrasting national contexts. Studies were conducted in Egypt, Indonesia, the Philippines, the Russian Federation, and Ukraine. In all cases, the potential iodine intake from iodised salt in selected food products was modelled according to the formula: quantity of salt per unit of food product × minimum regulated iodine level of salt at production × average daily per capita consumption of the product. The percent of adult recommended nutrient intake for iodine potentially provided by the average daily intake of bread and frequently consumed foods and condiments was from 10% to 80% at the individual product level. The potential contribution to iodine intake from the use of iodised salt in the processed food industry is of growing significance. National USI strategies should encourage co-operative industry engagement and include regulatory monitoring of iodised salt use in the food industry in order to achieve optimal population iodine status.
Dietary Composition Independent of Weight Loss in the Management of Non-Alcoholic Fatty Liver Disease
Authors: Eslamparast Tannaz , Tandon Puneeta , Raman Maitreyi
Published: July 2017

Poor dietary composition is an important factor in the progression of non-alcoholic fatty liver disease (NAFLD). The majority of NAFLD patients follow diets with overconsumption of simple carbohydrates, total and saturated fat, with reduced intake of dietary fiber and omega-3 rich foods. Although lifestyle modifications including weight loss and exercise remain the keystone of NAFLD management, modifying dietary composition with or without a calorie-restricted diet may also be a feasible and sustainable strategy for NAFLD treatment. In the present review article, we highlight the potential therapeutic role of a “high quality healthy diet” to improve hepatic steatosis and metabolic dysfunction in patients with NAFLD, independent of caloric restriction and weight loss. We provide a literature review evaluating the evidence behind dietary components including fiber-, meat- and omega-3-rich diets and, pending further evidence, we concur with the EASL-EASD-EASO Clinical Guidelines recommendation of the Mediterranean diet as the diet of choice in these patients.
Veterinary Pharmaceutics: An Opportunity for Interprofessional Education in New Zealand?
Authors: McDowell Arlene , Beard Rebekah , Brightmore Anna , Lu Lisa , McKay Amelia , Mistry Maadhuri , Owen Kate , Swan Emma , Young Jessica
Published: July 2017

Globally pharmacists are becoming increasingly involved in veterinary medicine; however, little is known about the level of interest for pharmacists playing a larger role in animal treatment in New Zealand. A key stakeholder in any progression of pharmacists becoming more involved in the practice of veterinary pharmacy is the veterinary profession. The aim of this study was to investigate views of veterinarians and veterinary students on the role of pharmacists supporting veterinarians with advice on animal medicines. Open interviews were conducted with veterinarians in Dunedin, New Zealand. Veterinary students at Massey University completed an online survey. Most veterinarians do not have regular communication with pharmacists regarding animal care, but believe it may be beneficial. In order to support veterinarians, pharmacists would need further education in veterinary medicine. Veterinary students believe there is opportunity for collaboration between professions provided that pharmacists have a better working knowledge of animal treatment. Most of the veterinary students surveyed perceive a gap in their knowledge concerning animal medicines, specifically pharmacology and compounding. While there is support for pharmacists contributing to veterinary medicine, particularly in the area of pharmaceutics, this is currently limited in New Zealand due to a lack of specialized education opportunities.
Effects of RAFT Agent on the Chloromethylstyrene Polymerizations in a Simultaneous Radiation Grafting System
Authors: Chen Jinhua , Seko Noriaki
Published: July 2017

Reversible addition-fragmentation chain transfer (RAFT) agent was added into a simultaneous radiation grafting system and its effects on graft polymerization and homopolymerization were investigated. Chloromethylstyrene (CMS) was graft polymerized onto ethylene-tetrafluoroethylene copolymer (ETFE) films under γ-ray sources via simultaneous irradiation. The non-grafted poly(CMS) in the grafted films were extracted by xylene at 120 °C. The poly(CMS) was characterized by NMR and GPC instruments. Addition of the RAFT agent suppressed both graft polymerization and homopolymerization. However, under a high concentration of RAFT agent, the homopolymerization in the monomer solution could occur through a typical RAFT polymerization while polymerization in the ETFE films proceeded via RAFT and conventional radical polymerization, resulting in poly(CMS) in the ETFE films with molecular weight dispersity higher than 1.0 but lower than that without RAFT agent. Furthermore, it was found that the molecular weight of the poly(CMS) in the ETFE films was several times higher than that of the poly(CMS) in the monomer solution.
Performance Evaluation for China’s Planned CO2-IPDA
Authors: Han Ge , Ma Xin , Liang Ailin , Zhang Tianhao , Zhao Yannan , Zhang Miao , Gong Wei
Published: July 2017

Active remote sensing of atmospheric XCO2 has several advantages over existing passive remote sensors, including global coverage, a smaller footprint, improved penetration of aerosols, and night observation capabilities. China is planning to launch a multi-functional atmospheric observation satellite equipped with a CO2-IPDA (integrated path differential absorption Lidar) to measure columnar concentrations of atmospheric CO2 globally. As space and power are limited on the satellite, compromises have been made to accommodate other passive sensors. In this study, we evaluated the sensitivity of the system’s retrieval accuracy and precision to some critical parameters to determine whether the current configuration is adequate to obtain the desired results and whether any further compromises are possible. We then mapped the distribution of random errors across China and surrounding regions using pseudo-observations to explore the performance of the planned CO2-IPDA over these regions. We found that random errors of less than 0.3% can be expected for most regions of our study area, which will allow the provision of valuable data that will help researchers gain a deeper insight into carbon cycle processes and accurately estimate carbon uptake and emissions. However, in the areas where major anthropogenic carbon sources are located, and in coastal seas, random errors as high as 0.5% are predicted. This is predominantly due to the high concentrations of aerosols, which cause serious attenuation of returned signals. Novel retrieving methods must, therefore, be developed in the future to suppress interference from low surface reflectance and high aerosol loading.
An Automatic Multi-Target Independent Analysis Framework for Non-Planar Infrared-Visible Registration
Authors: Sun Xinglong , Xu Tingfa , Zhang Jizhou , Zhao Zishu , Li Yuankun
Published: July 2017

In this paper, we propose a novel automatic multi-target registration framework for non-planar infrared-visible videos. Previous approaches usually analyzed multiple targets together and then estimated a global homography for the whole scene, however, these cannot achieve precise multi-target registration when the scenes are non-planar. Our framework is devoted to solving the problem using feature matching and multi-target tracking. The key idea is to analyze and register each target independently. We present a fast and robust feature matching strategy, where only the features on the corresponding foreground pairs are matched. Besides, new reservoirs based on the Gaussian criterion are created for all targets, and a multi-target tracking method is adopted to determine the relationships between the reservoirs and foreground blobs. With the matches in the corresponding reservoir, the homography of each target is computed according to its moving state. We tested our framework on both public near-planar and non-planar datasets. The results demonstrate that the proposed framework outperforms the state-of-the-art global registration method and the manual global registration matrix in all tested datasets.
Variation in the Characteristics of Everyday Life and Meaning of Urban Housing Due to the Transition of Social Structure: Focusing on Articles Published in Lifestyle Magazines
Authors: Kwon Hyun-ah , Kim Soomi
Published: July 2017

The patterns and characteristics of everyday life have been changing according to changes in social structure. However, South Korean apartment complexes as a representative urban housing type are still based on the Western tradition of modern working-class housing, and have been commodified in the context of consumer capitalism. Therefore, this research explores the contemporary lifestyles that should be supported in urban housing by analyzing the articles of lifestyle magazines. Based on this analysis, we derived the changed patterns of contemporary lifestyles in terms of residents’ characteristics, the relationship between individuals and family, the relationship between house and workplace, and the pursuing direction of residential space planning. These results can contribute to discover the contemporary characteristics of everyday life and its lifestyle; define the changed meaning of urban housing; and reduce the gap between living space and their lives for urban and social sustainability.
Assessment of Two Soil Fertility Indexes to Evaluate Paddy Fields for Rice Cultivation
Authors: Delsouz Khaki Bahareh , Honarjoo Naser , Davatgar Naser , Jalalian Ahmad , Torabi Golsefidi Hosein
Published: July 2017

Assessing soil fertility is essential to help identify strategies with less environmental impact in order to achieve more sustainable agricultural systems. The main objective of this research was to assess two soil fertility evaluation approaches in paddy fields for rice cultivation, in order to develop a user-friendly and credible soil fertility index (SFI). The Square-Root method was used as a parametric approach, while the Joint Fuzzy Membership functions as a fuzzy method with adapted criteria definition tables, were used to compute SFI. Results indicated that both of the methods determined the major soil limiting factors for rice cultivation clearly, and soil fertility maps established using GIS (Geographic Information System) could be helpful for decision makers. The coefficients of determination (R2) for the linear regression between the two SFI values and rice yields were relatively high (0.63 and 0.61, respectively). Additionally, the two SFI were significantly correlated to each other (r = 0.68, p < 0.05). The study results demonstrated that both of the methods provide reliable and valuable information. Compared to the fuzzy method, the procedure of the parametric method is easier but may be expensive and time-consuming. However, the fuzzy method, with carefully chosen indicators, can adequately evaluate soil fertility and provide useful information for decision making.
Types of Green Innovations: Ways of Implementation in a Non-Green Industry
Authors: Calza Francesco , Parmentola Adele , Tutore Ilaria
Published: July 2017

Attention to environmental sustainability represents an essential issue for the companies that, in order to integrate environment into their strategies, are producing specific innovations that have also positive environmental outcomes. Implementing green innovations represents a great challenge for non-green companies because it often requires the acquisition of new resources and competences that differ significantly from their existing competences. This paper attempts to propose a theoretical framework that classifies green innovations according their impact on company’s competences and analyses how green innovations can be implemented. Given the complexity of the issue and the variability of situations, we use a multiple case study analysis of several green innovations developed in a non-green industry, namely the automotive sector. Indeed, this is one that produces the highest environmental impact and, in recent years, it has been subjected to increasing regulatory restrictions. Companies operating in a non-green industry that implement disruptive, radical and architectural green innovations can initiate market and technological partnerships to mitigate against such internal weaknesses, such as the lack of technological capabilities and market knowledge. The collaboration helps firms to access new competences and capabilities useful to change or develop new technology capabilities and market knowledge more easily and with lower costs.
Accelerating Sustainability by Hydropower Development in China: The Story of HydroLancang
Authors: Zhang Yan
Published: July 2017

Sustainable development is a shared responsibility. Accelerating sustainability of water–energy–people nexus and building a common awareness of issues pertaining to sustainable development are essential for any sort of success in this direction. Hydropower has been a useful sustainable energy for development, yet highly controversial. This paper reviews the overall situation of hydropower development and China’s energy reforms and policies, accompanied with a case study of hydropower development the Lancang River by the HydroLancang, aiming to illustrate the two opposite sides of hydropower development—economy and environment. The paper concludes with a neutral view of hydropower as the necessary facilitator for development. Water is a shared responsibility. Hydropower might not be the optimum solution to eliminate the tension between human demand of energy and finite natural resource and the rising pressure of climate change worldwide, but it serves well as an “Electricity Bridge” before better alternatives become available. This is a more balanced view of hydropower rather than two extreme viewpoints that present themselves: on the one hand, exaggerated claims of the human power to tame the wild river, and, on the other hand, the idealistic fantasy of preserving nature by abandoning all human activity.
Development of a High-Speed Current Injection and Voltage Measurement System for Electrical Impedance Tomography-Based Stretchable Sensors
Authors: Russo Stefania , Nefti-Meziani Samia , Carbonaro Nicola , Tognetti Alessandro
Published: July 2017

Electrical impedance tomography (EIT) is an imaging method that can be applied over stretchable conductive-fabric materials to realize soft and wearable pressure sensors through current injections and voltage measurements at electrodes placed at the boundary of a conductive medium. In common EIT systems, the voltage data are serially measured by means of multiplexers, and are hence collected at slightly different times, which affects the real-time performance of the system. They also tend to have complicated hardware, which increases power consumption. In this paper, we present our design of a 16-electrode high-speed EIT system that simultaneously implements constant current injection and differential potential measurements. This leads to a faster, simpler-to-implement and less-noisy technique, when compared with traditional EIT approaches. Our system consists of a Howland current pump with two multiplexers for a constant DC current supply, and a data acquisition card. It guarantees a data collection rate of 78 frames/s. The results from our conductive stretchable fabric sensor show that the system successfully performs voltage data collection with a mean signal-to-noise ratio (SNR) of 55 dB, and a mean absolute deviation (MAD) of 0.5 mV. The power consumption can be brought down to 3 mW; therefore, it is suitable for battery-powered applications. Finally, pressure contacts over the sensor are properly reconstructed, thereby validating the efficiency of our EIT system for soft and stretchable sensor applications.
Venomics of Remipede Crustaceans Reveals Novel Peptide Diversity and Illuminates the Venom’s Biological Role
Authors: Von Reumont Björn , Undheim Eivind , Jauss Robin-Tobias , Jenner Ronald
Published: July 2017

We report the first integrated proteomic and transcriptomic investigation of a crustacean venom. Remipede crustaceans are the venomous sister group of hexapods, and the venom glands of the remipede Xibalbanus tulumensis express a considerably more complex cocktail of proteins and peptides than previously thought. We identified 32 venom protein families, including 13 novel peptide families that we name xibalbins, four of which lack similarities to any known structural class. Our proteomic data confirm the presence in the venom of 19 of the 32 families. The most highly expressed venom components are serine peptidases, chitinase and six of the xibalbins. The xibalbins represent Inhibitory Cystine Knot peptides (ICK), a double ICK peptide, peptides with a putative Cystine-stabilized α-helix/β-sheet motif, a peptide similar to hairpin-like β-sheet forming antimicrobial peptides, two peptides related to different hormone families, and four peptides with unique structural motifs. Remipede venom components represent the full range of evolutionary recruitment frequencies, from families that have been recruited into many animal venoms (serine peptidases, ICKs), to those having a very narrow taxonomic range (double ICKs), to those unique for remipedes. We discuss the most highly expressed venom components to shed light on their possible functional significance in the predatory and defensive use of remipede venom, and to provide testable ideas for any future bioactivity studies.