bluuebunny/crossref_metadata_2025 huggingface dataset:
A comparative clinical trial to evaluate the efficacy of Dashamoola Taila Karnapoorana and Nasya and orally Dashamoola Ghrita in Badhirya (sensory neural hearing loss)
Authors: Shashikala K.  , Gururaj N  , Veerayya Hiremath
Published: May 2023

It is estimated that by 2050 over 900 million people will have disabling hearing loss. In Ayurveda hearing loss is described as Badhirya, which can be treated with Nasya, Karna Poorana, oral administration of Vatahara Ghrita and other Vatashamana procedures. This is a randomized comparative clinical study of 3 groups with 30 patients in each; namely Group-A of Dashamoola Taila Karnapoorana, Group-B of Dashamoola Taila Nasya & Group C of Dashamoola Taila Karnapoorana and Dashamoola Taila Nasya. Dashamoola Ghrita was advised for oral administration to all groups. Total Treatment duration was of 210 days i.e., 7 days (Day 1-7), followed by 48 days administration of Ghrita (Day 22-70) and follow up after 140 days. There was mild improvement in hearing in both ears with slight improvement in pure tone audiometric values. There was clinical improvement seen in all three groups, group C has better results compared to other two groups. Statistically there is significant result within the group and no statistical significance between the groups. Since, combined treatment using Dashamoola Taila Nasya and Karnapoorana and Dashamoola Ghrita orally has shown better results, following complete Chikitsasutra would be helpful in management of Badhirya than treating with single line of treatment.
A conceptual review of Artavavaha Srotas and its Viddha Lakshan
Authors: Durgeshvari  , Dileep Kumar Singh  , Kuldeep Kumar
Published: May 2023

According to Ayurvedic Samhitas, Srotas is a structural and functional unit of the body. Srotas are the hollow spaces or channels which are responsible for any movement or transformation. There are many types of Srotas mention by Acharyas. Maharshi Charaka explains Srotas as a medicinal aspect and Maharshi Sushruta explains Srotas according to surgical aspect. Artavavaha Srotas is Antarmukh Srotas which are also known as Yogawahi Srotas. It is similar to the female reproductive system in modern medical science. As per Maharshi Sushruta, Artavavaha Srotas are two in number and their Moolsthana is Garbhashaya and Artavavahi Dhamanya. Any trauma to this Srotas causes Bhandhayatva (infertility), Artavanasha (amenorrhea) and Maithuna Asahishnuta (dyspareunia). In this study description of Ayurvedic concept along with discussion regarding the patho-clinical perspective of Artavavaha Srotas and its Viddha Lakshan in light of modern science.
Effect of Garavisha and Dushivisha on Human Population - In Present Era
Authors: Panthi Sheetal , Sangeeta Bhagat  , S.R. Inchulkar  , Yuvraj Kaushik
Published: May 2023

Ayurveda give more importance to promotion of health and prevention of disease rather than disease and cure. Poison is in everything, only the dose decides its effects. One of the hidden poisons is the concocted poison known as Garavisha. Ayurveda explains this Visha as the combination of poisonous or non-poisonous substances which produces chronic toxicity by interfering in the process of digestion. People unknowingly consume various combination substances which are harmful to health. The insect powder, human waste products are some of the agents of Garavisha. Many food items are consume daily contain some of the natural toxins. By knowing these food items can be reduced the chances of toxicity. Ayurveda defines Garavisha in a marvellous way and describes the treatment as well like Vamana Karma, Agadpaana. Ayurveda plays an important role in management of Garavisha. Dushivisha is one of the unique concepts explained in Ayurveda. It is a type of toxin which remains inside the body for long & then produces various ill effects on the body. In present era, people are exposing to various toxins in day-to-day life which is causing various health problems. There are many such illnesses where treatment does not work, as it is not eliminating the root cause. The ancient concept of Dushivisha seems to be more relevant in this context. So, this topic is selected to study the concept comprehensively with the object of highlighting it with modern approach.
HAK KREDITOR DENGAN TAGIHAN PIUTANG TERTOLAK DALAM PROSES PENUNDAAN KEWAJIBAN PEMBAYARAN UTANG
Authors: Sihabudin Sihabudin , Adhitama Edo
Published: May 2023

One of the stages in delaying payment of receivables obligations (PKPU) is the verification of receivables. There may be a possibility that the claim for receivables being rejected at the verification stage may occur, but there is no legal remedy that can be taken by the creditor, either ordinary or extraordinary legal remedies. This article aims to analyze the legal protection of creditors' receivables which are rejected at the receivables verification stage by administrators in the PKPU process and the authority of the supervisory judge in terms of the creditor's bill being rejected at the receivables verification stage. This normative research uses a statutory approach. The results show that Law Number 37 of 2004 does not regulate legal remedies if receivables are rejected in the accounts receivable verification. Efforts are made when this happens, the supervisory judge has the authority to reconcile creditors and debtors in determining. Thus, the debtor does not need to wait for the emergence of a settlement homologation if the bill is rejected in the verification of receivables to submit an appeal to the Supreme Court.
PRISON ESCAPE VIEWED FROM ISLAMIC LAW PERSPECTIVES (A Case Study at Muara Labuh Prison)
Authors: Salma Salma , Hamdi Riki , Hidayat Taufik
Published: May 2023

In Indonesia, there have been numerous cases of people escaping from prison including the Muara Labuh Prison. This research analyze the prison conditions, the cases that occurred there, the motives behind the escape, the responsibility of the warden, and how Islamic law views escape. Data were collected through observation of prison conditions and interviews. Data analysis was performed in several stages, including data reduction, display, and verification techniques, then, narrated using a qualitative approach and Islamic law. The results revealed three cases of inmates escaping from this prison. They have a variety of reasons for this, including an inability to restrain sexual desires, being unable to serve very long sentences, depression, and poor prison security, which is the warden's responsibility. Prison escape is not justified in Islamic law due to the necessity to obey state rules that are not specifically regulated in the Qur'an and Sunnah.
Characterizing the Discourse of Popular Diets to Describe Information Dispersal and Identify Leading Voices, Interaction, and Themes of Mental Health: Social Network Analysis
Authors: Eaton Melissa C , Probst Yasmine C , Smith Marc A
Published: May 2023

Background

Social media has transformed the way health messages are communicated. This has created new challenges and ethical considerations while providing a platform to share nutrition information for communities to connect and for information to spread. However, research exploring the web-based diet communities of popular diets is limited.

Objective

This study aims to characterize the web-based discourse of popular diets, describe information dissemination, identify influential voices, and explore interactions between community networks and themes of mental health.

Methods

This exploratory study used Twitter social media posts for an online social network analysis. Popular diet keywords were systematically developed, and data were collected and analyzed using the NodeXL metrics tool (Social Media Research Foundation) to determine the key network metrics (vertices, edges, cluster algorithms, graph visualization, centrality measures, text analysis, and time-series analytics).

Results

The vegan and ketogenic diets had the largest networks, whereas the zone diet had the smallest network. In total, 31.2% (54/173) of the top users endorsed the corresponding diet, and 11% (19/173) claimed a health or science education, which included 1.2% (2/173) of dietitians. Complete fragmentation and hub and spoke messaging were the dominant network structures. In total, 69% (11/16) of the networks interacted, where the ketogenic diet was mentioned most, with depression and anxiety and eating disorder words most prominent in the “zone diet” network and the least prominent in the “soy-free,” “vegan,” “dairy-free,” and “gluten-free” diet networks.

Conclusions

Social media activity reflects diet trends and provides a platform for nutrition information to spread through resharing. A longitudinal exploration of popular diet networks is needed to further understand the impact social media can have on dietary choices. Social media training is vital, and nutrition professionals must work together as a community to actively reshare evidence-based posts on the web.
Exploring the Acceptability of Text Messages to Inform and Support Shared Decision-making for Colorectal Cancer Screening: Online Panel Survey (Preprint)
Authors: Hwang Soohyun , Lazard Allison J , Reffner Collins Meredith K , Brenner Alison T , Heiling Hillary M , Deal Allison M , Crockett Seth D , Reuland Daniel S , Elston Lafata Jennifer
Published: May 2023

BACKGROUND

While online portals may be helpful to engage patients in shared decision-making at the time of cancer screening, because of known disparities in patient portal use, sole reliance on portals to support cancer screening decision-making could exacerbate well-known disparities in this health care area. Innovative approaches are needed to engage patients in health care decision-making and to support equitable shared decision-making.

OBJECTIVE

We assessed the acceptability of text messages to engage sociodemographically diverse individuals in colorectal cancer (CRC) screening decisions and support shared decision-making in practice.

METHODS

We developed a brief text message program offering educational information consisting of components of shared decision-making regarding CRC screening (eg, for whom screening is recommended, screening test options, and pros/cons of options). The program and postprogram survey were offered to members of an online panel. The outcome of interest was program acceptability measured by observed program engagement, participant-reported acceptability, and willingness to use similar programs (behavioral intent). We evaluated acceptability among historically marginalized categories of people defined by income, literacy, and race.

RESULTS

Of the 289 participants, 115 reported having a low income, 146 were Black/African American, and 102 had less than extreme confidence in their health literacy. With one exception, we found equal or greater acceptability, regardless of measure, within each of the marginalized categories of people compared to their counterparts. The exception was that participants reporting an income below US $50,000 were less likely to engage with sufficient content of the program to learn that there was a choice among different CRC screening tests (difference –10.4%, 95% CI –20.1 to –0.8). Of note, Black/African American participants reported being more likely to sign up to receive text messages from their doctor’s office compared to white participants (difference 18.7%, 95% CI 7.0-30.3).

CONCLUSIONS

Study findings demonstrate general acceptance of text messages to inform and support CRC screening shared decision-making.
Domesticating Social Alarm Systems in Nursing Homes: Qualitative Study of Differences in the Perspectives of Assistant Nurses (Preprint)
Authors: Chang Fangyuan , Östlund Britt , Kuoppamäki Sanna
Published: May 2023

BACKGROUND

New social alarm solutions are viewed as a promising approach to alleviate the global challenge of an aging population and a shortage of care staff. However, the uptake of social alarm systems in nursing homes has proven both complex and difficult. Current studies have recognized the benefits of involving actors such as assistant nurses in advancing these implementations, but the dynamics by which implementations are created and shaped in their daily practices and relations have received less attention.

OBJECTIVE

Based on domestication theory, this paper aims to identify the differences in the perspectives of assistant nurses when integrating a social alarm system into daily practices.

METHODS

We interviewed assistant nurses (n=23) working in nursing homes to understand their perceptions and practices during the uptake of social alarm systems.

RESULTS

During the four domestication phases, assistant nurses were facing different challenges including (1) system conceptualization; (2) spatial employment of social alarm devices; (3) treatment of unexpected issues; and (4) evaluation of inconsistent competence in technology use. Our findings elaborate on how assistant nurses have distinct goals, focus on different facets, and developed diverse coping strategies to facilitate the system domestication in different phases.

CONCLUSIONS

Our findings reveal a divide among assistant nurses in terms of domesticating social alarm systems and stress the potential of learning from each other to facilitate the whole process. Further studies could focus on the role of collective practices during different domestication phases to enhance the understanding of technology implementation in the contexts of complex interactions within a group.
What Predicts App Engagement? The Association Between Motivation Measures and Meditation App Use Among New Subscribers (Preprint)
Authors: Sullivan Mariah , Cloonan Sara , Huberty Jennifer , Stecher Chad
Published: May 2023

BACKGROUND

Mindfulness meditation apps are associated with significant health benefits, yet many new app subscribers have low engagement and are unlikely to attain these benefits.

OBJECTIVE

The purpose of this study was to determine which individual characteristics predict app usage during the first eight weeks after newly subscribing to a meditation app.

METHODS

New subscribers to the Calm app completed a baseline survey and objective app usage data were collected over their first eight weeks. The baseline survey measured demographics, personality traits, intrinsic motivation for meditation, and symptoms of stress, anxiety, and depression. Regression models were used to assess the relationship between these self-reported characteristics and five app engagement outcomes: 1) days with any app session, 2) average daily minutes including all app session types, 3) an indicator for completing any meditation session, 4) days with any meditation sessions, and 5) average daily minutes of meditation.

RESULTS

We enrolled 304 participants who were primarily women (79%), White (82%), and had a mental health diagnosis (77%). Intrinsic motivation for meditation was the strongest predictor of app use over the first eight weeks and was associated with 3.63 greater odds of completing any meditation session (95% CI 2.10,6.27; P < 0.01), more days with meditation sessions (1.75 IRR, 95% CI 1.46,2.11; P < 0.01), and 0.32 more average daily meditation minutes (95% CI 0.14,0.49; P < 0.01). Among the individual components of the Intrinsic Motivation Inventory, “feeling pressure to meditate” was associated with fewer days of meditation (0.73 IRR, 95% CI 0.56,0.96; P =.004) and 0.47 fewer minutes of meditation (95% CI -0.74,-0.20; P <.001).

CONCLUSIONS

High intrinsic motivation for meditation was the strongest predictor of meditation app use among new subscribers’ first eight weeks, with a particularly strong negative relationship when motivation came from feeling pressure to use the app. These results suggest that pressure is a harmful source of motivation for meditation, and that future behavioral interventions should attempt to reduce sources of pressure to meditate in order to better maintain meditation performance.

CLINICALTRIAL

This trial was not preregistered
A Random Forest Algorithm for Assessing Risk Factors Associated With Chronic Kidney Disease: Observational Study (Preprint)
Authors: Liu Pei , Liu Yijun , Liu Hao , Xiong Linping , Mei Changlin , Yuan Lei
Published: May 2023

BACKGROUND

The prevalence and mortality rate of chronic kidney disease (CKD) are increasing year by year, and it has become a global public health issue. The economic burden caused by CKD is increasing at a rate of 1% per year. CKD is highly prevalent and its treatment cost is high but unfortunately remains unknown. Therefore, early detection and intervention are vital means to mitigate the treatment burden on patients and decrease disease progression.

OBJECTIVE

In this study, we investigated the advantages of using the random forest (RF) algorithm for assessing risk factors associated with CKD.

METHODS

We included 40,686 people with complete screening records who underwent screening between January 1, 2015, and December 22, 2020, in Jing’an District, Shanghai, China. We grouped the participants into those with and those without CKD by staging based on the glomerular filtration rate staging and grouping based on albuminuria. Using a logistic regression model, we determined the relationship between CKD and risk factors. The RF machine learning algorithm was used to score the predictive variables and rank them based on their importance to construct a prediction model.

RESULTS

The logistic regression model revealed that gender, older age, obesity, abnormal index estimated glomerular filtration rate, retirement status, and participation in urban employee medical insurance were significantly associated with the risk of CKD. On RF algorithm–based screening, the top 4 factors influencing CKD were age, albuminuria, working status, and urinary albumin-creatinine ratio. The RF model predicted an area under the receiver operating characteristic curve of 93.15%.

CONCLUSIONS

Our findings reveal that the RF algorithm has significant predictive value for assessing risk factors associated with CKD and allows the screening of individuals with risk factors. This has crucial implications for early intervention and prevention of CKD.
Standardizing Corneal Transplantation Records Using openEHR: Case Study (Preprint)
Authors: Ferreira Diana , Neto Cristiana , Hak Francini , Abelha António , Santos Manuel , Machado José
Published: May 2023

BACKGROUND

Corneal transplantation, also known as keratoplasty, is a widely performed surgical procedure that aims to restore vision in patients with corneal damage. The success of corneal transplantation relies on the accurate and timely management of patient information, which can be enhanced using electronic health records (EHRs). However, conventional EHRs are often fragmented and lack standardization, leading to difficulties in information access and sharing, increased medical errors, and decreased patient safety. In the wake of these problems, there is a growing demand for standardized EHRs that can ensure the accuracy and consistency of patient data across health care organizations.

OBJECTIVE

This paper proposes the use of openEHR structures for standardizing corneal transplantation records. The main objective of this research was to improve the quality and interoperability of EHRs in corneal transplantation, making it easier for health care providers to capture, share, and analyze clinical information.

METHODS

A series of sequential steps were carried out in this study to implement standardized clinical records using openEHR specifications. These specifications furnish a methodical approach that ascertains the development of high-quality clinical records. In broad terms, the methodology followed encompasses the conduction of meetings with health care professionals and the modeling of archetypes, templates, forms, decision rules, and work plans.

RESULTS

This research resulted in a tailored solution that streamlines health care delivery and meets the needs of medical professionals involved in the corneal transplantation process while seamlessly aligning with contemporary clinical practices. The proposed solution culminated in the successful integration within a Portuguese hospital of 3 key components of openEHR specifications: forms, Decision Logic Modules, and Work Plans. A statistical analysis of data collected from May 1, 2022, to March 31, 2023, allowed for the perception of the use of the new technologies within the corneal transplantation workflow. Despite the completion rate being only 63.9% (530/830), which can be explained by external factors such as patient health and availability of donor organs, there was an overall improvement in terms of task control and follow-up of the patients’ clinical process.

CONCLUSIONS

This study shows that the adoption of openEHR structures represents a significant step forward in the standardization and optimization of corneal transplantation records. It offers a detailed demonstration of how to implement openEHR specifications and highlights the different advantages of standardizing EHRs in the field of corneal transplantation. Furthermore, it serves as a valuable reference for researchers and practitioners who are interested in advancing and improving the exploitation of EHRs in health care.
IRONMAN® Hawaii is the fastest race course for age group triathletes (Preprint)
Authors: Knechtle Beat , Valero David , Villiger Elias , Thuany Mabliny , Nikolaidis Pantelis , Cuk Ivan , Andrade Marilia , Forte Pedro , Weiss Katja
Published: May 2023

BACKGROUND

The IRONMAN® triathlon is a popular multi-sport, where age group athletes often strive to qualify for the IRONMAN® World Championship in Hawaii. The aim of the present study was to investigate the location of the fastest IRONMAN® racecourses for age group triathletes. This knowledge will help IRONMAN® age group triathletes find the best racecourse, considering their strengths and weaknesses, to qualify.

OBJECTIVE

To determine the fastest IRONMAN® racecourse for age group triathletes using the machine learning XG Boost algorithm.

METHODS

We collected and analyzed 677,702 age group finishers' records from 228 countries participating in the IRONMAN® competitions held between 2002 and 2022 across 67 event locations. A predictive model was built with the race finish time as the predicted variable and the triathlete’s gender, age group, country of origin, and event location as predictors. The model was trained with 75% of the available data and was validated against the remaining 25%. Several model interpretability tools were used to explore how each predictor contributed to the model's predictive power, from which we intended to infer whether one or more predictors were more important than the others.

RESULTS

The XG Boost Regressor model analysis indicated that the IRONMAN® Hawaii course was the fastest racecourse and that male athletes aged 35 years and younger were the fastest. Most of the finishers were competing in IRONMAN® triathlons held in the USA, such as IRONMAN® Wisconsin, Florida, Lake Placid, Arizona, and Hawaii, where the IRONMAN® World Championship takes place. Still, the fastest average times were achieved in IRONMAN® Hawaii, Austria, Copenhagen, Brazil Florianopolis, and Barcelona. Most of the successful IRONMAN® finishers originated from the United States of America, followed by athletes from the United Kingdom, Canada, Australia, Germany, and France. The best mean IRONMAN® race times were achieved by athletes from Austria, Germany, Belgium, Switzerland, Finland, and Denmark.

CONCLUSIONS

Age group athletes who have better placements in faster events and intend to qualify for IRONMAN® Hawaii may participate in IRONMAN® Austria, Copenhagen, Brazil Florianopolis, and Barcelona in order to achieve a fast race time to qualify for the IRONMAN® World Championship in Hawaii.
Women Are Underrepresented Among Authors of Retracted Publications: Retrospective Study of 134 Medical Journals (Preprint)
Authors: Sebo Paul , Schwarz Joëlle , Achtari Margaux , Clair Carole
Published: May 2023

UNSTRUCTURED

We examined the gender distribution of authors of retracted articles in 134 medical journals across 10 disciplines, compared it with the gender distribution of authors of all published articles, and found that women were underrepresented among authors of retracted articles, and, in particular, of articles retracted for misconduct.
Hybrid Business Models for AI and AR/VR Healthcare Solutions: Synergies, Complementarities, and Implementation Challenges (Preprint)
Authors: Kulkov Ignat , Kulkova Julia , Rohrbeck Rene
Published: May 2023

UNSTRUCTURED

The rapid advancements in Artificial Intelligence (AI), Augmented Reality (AR), and Virtual Reality (VR) technologies present significant opportunities for the healthcare industry. This paper explores the development and optimization of hybrid business models that leverage the combined potential of AI, AR, and VR in healthcare. We examine the synergies and complementarities of these technologies, focusing on their ability to enhance diagnostics, personalized treatment, and medical training. Furthermore, we discuss implementation challenges, including technological, organizational, and cultural barriers, as well as data privacy, security, and regulatory compliance issues. Drawing from case studies of successful hybrid business models in healthcare, we analyze the factors contributing to their success and provide insights for other healthcare organizations and technology companies. Finally, we offer recommendations for creating and optimizing hybrid business models, addressing implementation challenges, and fostering collaboration among stakeholders. Our findings contribute to the literature on AI, AR, and VR in healthcare and provide practical implications for healthcare organizations and technology companies seeking to innovate in this rapidly evolving field.
Development and Testing of a Mobile App to Collect Social Determinants of Health Data in Cancer Settings: Interview Study (Preprint)
Authors: Oyedele Natasha K , Lansey Dina G , Chiew Calvin , Chan Cupid , Quon Harry , Dean Lorraine T
Published: May 2023

BACKGROUND

Social determinants of health (SDOH) such as lack of basic resources, housing, transportation, and social isolation play an important role for patients on the cancer care continuum. Health systems’ current technological solutions for identifying and managing patients’ SDOH data largely focus on information recorded in the electronic health record by providers, which is often inaccessible to patients to contribute to or modify.

OBJECTIVE

We developed and tested a patient-centric SDOH screening tool designed for use on patients’ personal mobile phone that preserves patient privacy and confidentiality, collects information about the unmet social needs of patients with cancer, and communicates them to the provider.

METHODS

We interviewed 22 patients with cancer, oncologists, and social workers associated with a US-based comprehensive cancer center to better understand how patients’ SDOH information is collected and reported. After triangulating data obtained from thematic analysis of interviews, an environmental scan, and a literature search of validated tools to collect SDOH data, we developed an SDOH screening tool mobile app and conducted a pilot study of 16 dyadic pairs of patients and cancer care team members at the same cancer center. We collected patient SDOH data using 36 survey items covering 7 SDOH domains and used validated scales and follow-up interviews to assess the app’s usability and acceptability among patients and cancer care team members.

RESULTS

Formative interviews with patients and care team members revealed that transportation, financial challenges, food insecurity, and low health literacy were common SDOH challenges and that a mobile app that collected those data, shared those data with care team members, and offered supportive resources could be useful and valuable. In the pilot study, 25% (4/16) of app-using patients reported having at least one of the abovementioned social needs; the most common social need was social isolation (7/16, 44%). Patients rated the mobile app as easy to use, accurately capturing their SDOH, and preserving their privacy but suggested that the app could be more helpful by connecting patients to actual resources. Providers reported high acceptability and usability of the app.

CONCLUSIONS

Use of a brief, patient-centric, mobile app–based SDOH screening tool can effectively capture SDOH of patients with cancer for care team members in a way that preserves patient privacy and that is acceptable and usable for patients and care team members. However, only collecting SDOH information is not sufficient; usefulness can be increased by connecting patients directly to resources to address their unmet social needs.

CLINICALTRIAL
La pervivencia histórica del fascismo. Reflexiones desde la memoria democrática europea
Authors: Sánchez-Moreno Manuel
Published: May 2023

El proyecto europeo de unificación surgió como consecuencia de enfrentar a los fascismos que asolaron este continente. Sin embargo, esta lucha no ha cesado, ya que diversas características fascistas han pervivido en una serie de movimientos abiertamente neofascistas y en partidos políticos que operan desde el Parlamento Europeo. Sin la violencia explícita de fascismos y neofascismos, estos posfascismos parlamentarios siguen conservando las formas de exclusión de los fascismos históricos y las características contrarias a los derechos humanos, al Estado de derecho y a los valores de la Unión Europea. La solución planteada se sustenta en una serie de medidas que apoyan la memoria democrática. Siguiendo una metodología de análisis de contenidos, perseguiremos el objetivo de este estudio, es decir, observar las distintas formas que han ido adoptando en Europa los fascismos.
Effect of Concentrations of Biocementation Solution on Enzyme Induced Calcium Carbonate Precipitation (EICP)
Authors: Pradeep Kavya , K Keerthi Raj
Published: May 2023

Abstract: The need to accommodate a growing global population has become major concern in many societies and has pushed human inventiveness to new levels. There is an increase in need for engineering technologies to improve the mechanical properties of the ground. Mostly soil strengthening is done by applying cement or chemical products to enhance the mechanical properties of soil. However, the usage of those products can possibly disturb improved soil and the production process of cement and chemical products can create harmful products. Enzyme Induced Calcium Carbonate Precipitation (EICP) is one sustainable method where calcium carbonate precipitation occurs via hydrolysis of urea (ureolysis) catalysed by plant-extracted urease enzyme for soil improvement . This study analysed the effect of different concentrations of urea- CaCl2 (0.5M, 1M, 1.5M) and urease enzyme (5 g/l) which forms the biocementation solution on the mechanical properties of soil. Direct Shear test is done to analyse the shear strength parameters. The optimum EICP treatment solution was obtained as urea- CaCl2 (1 M) at urease enzyme (5 g/l). It was observed that there was an increase in cohesion (0.16kg/cm2 ) and angle of internal friction (35º) at 7 days was to cohesion(0.18kg/cm2 ) and angle of internal friction (36º) at 14 days .
GAGASAN DESAIN ARSITEKTUR CAHAYA DAN BAYANGAN DI APARTEMEN BERTINGKAT RENDAH DI TAMAN KE-PUTIH SURABAYA
Authors: Wahyudi Muhammad , Effendy Machmud
Published: May 2023

Kawasan perkotaan yang semakin berkembang memberikan sisi positif dan negatif khususnya di Kota Surabaya. Salah satu sisi positif dari perkembangan kawasan perkotaan adalah kemajuan ekonomi dan bertambahnya lapangan pekerjaan, di sisi negatif berdampak pada bertambahnya kepadatan penduduk dan persaingan. Jumlah penduduk Kota Surabaya pada bulan September 2020 menurut hasil SP2020 adalah sebanyak 2,87 juta jiwa. Dengan luas wilayah 326,81 km2 persegi, kepadatan penduduk Kota Surabaya berdasarkan hasil sensus penduduk 2020 sebanyak 8.795 jiwa per km2. Melihat hal tersebut untuk memenuhi kebutuhan tempat tinggal banyak tumbuhnya apartemen di kota Surabaya baik bertingkat tinggi ataupun tingkat rendah, dengan munculnya apartemen bertingkat rendah dimana jauh dari sinar matahari sehingga cenderung lebih sejuk, dengan memaksimalkan pencahayaan alami dan mengatur bentuk pencahayaan dan bayangan sehingga mendapat bentukan sesuai kaidah-kaidah Arsitektur. Hasil Gagasan menunjukkan pengaplikasian bukaan pada fasad bangunan Apartemen bertingkat rendah memiliki kinerja pencahayaan alami yang sudah memenuhi standar pencahayaan untuk beraktivitas. Pengaplikasian pola tata masa, bentuk yang ditinjau dari arah hadap lokasi, dan juga pembagian fungsi ruang. Selain itu dengan penambahan bukaan pada ruangan dapat meningkatkan iluminan dan daylight factor ruang, yang memperhatikan dua aspek utama yaitu kecukupan pencahayaan & kenyamanan visual.Kata kunci: Desain Arsitektur , cahaya dan bayangan di apartemen bertingkat rendah
REHABILITASI JARINGAN IRIGASI UNTUK PENINGKATAN PRODUKSI PERTANIAN
Authors: Astutik Sri , Suhardi Diding
Published: May 2023

Pertumbuhan penduduk yang sangat pesat, di satu sisi menimbulkan suatu permasalahan yaitu meningkatnya kebutuhan akan bahan pangan. sehingga perlu dipikirkan berbagai usaha untuk lebih meningkatkan hasil pertanian dan mencegah terjadinya kesenjangan yang tinggi antara tingkat kebutuhan dan tingkat pemenuhan bahan makanan dan juga meningkatkan taraf hidup petani. Salah satu cara yang dapat dilakukan adalah mengoptimalkan lahan pertanian yang tersedia dengan panca usaha tani dan pengairan yang optimal. Oleh karena itu diperukan jaringan irigasi serta bangunan irigasi dalam keadaan baik. Seperti halnya di Jaringan Irigasi Daerah Irigasi Ketandan di Kabupaten Kediri dengan luas 1.637 Ha yang terdapat kerusakan pada Saluran Sekunder Klampitan sepanjang 1.355 m menyebabkan banyak kehilangan air, sehingga lahan tidak mendapatkan air sesuai kebutuhan yang menyebabkan produktifitas pertanian pada Daerah Irigasi Ketandan menurun.
Work context and family well-being: the role of psychological capital and the organizational culture
Authors: Gabardo-Martins Larissa Maria David , Ferreira Maria Cristina , Valentini Felipe
Published: May 2023

Family-work conflict and enrichment are closely related processes. This study used the Work-Family Resources Model to investigate the direct effects of a demand (perceived work demands) and a contextual job resource (social support at work) on an outcome in the family (flourishing in the family), as well as the mediating role of a personal resource (positive psychological capital) and the moderating role of a macro resource (organizational culture associated with the employees’ values of satisfaction and wellbeing) in these relationships. The sample consisted of 1052 Brazilian workers of both sexes (72.5 % women) from 50 organizations. The results found in Multilevel Structural Equation Modeling provided empirical support for the model by confirming the relationships that were tested. These findings entail important theoretical and practical implications for the family-work relationship, in demonstrating how the different processes imbricated in the work-family interface can occur, and how they can contribute to the quality of life in the family context.
L2-estimates of error in homogenization of parabolic equations with correctors taken into account
Authors: Pastukhova S. E.
Published: May 2023

We consider second-order parabolic equations with bounded measurable \(\varepsilon\)-periodic coefficients. To solve the Cauchy problem in the layer \( R^d \times(0,T) \) with the nonhomogeneous equation, we obtain approximations in the norm \(\|\cdot\|_{L^2(R^d\times(0,T))}\) with remainder of order \(\varepsilon^2\) as \(\varepsilon \to 0.\)
Integro-differential equations in Banach spaces and analytic resolving families of operators
Authors: Fedorov V. E. , Godova A. D.
Published: May 2023

We study a class of equations in Banach spaces with a Riemann–Liouville-type integro-differential operator with an operator-valued convolution kernel. The properties of \(k\)-resolving operators of such equations are studied and the class \(\mathcal

A_{m,K,\chi}\) of linear closed operators is defined such that the belonging to this class is necessary and, in the case of commutation of the operator with the convolution kernel, is sufficient for the existence of analytic in the sector \(k\)-resolving families of operators of the equation under study. Under certain additional conditions on the convolution kernel, we prove theorems on the unique solvability of the nonhomogeneous linear equation of the class under consideration if the nonhomogeneity is continuous in the norm of the graph of the operator from the equation or Hölder continuous. We obtain the theorem on sufficient conditions on an additive perturbation of an operator of the class \(\mathcal A_{m,K,\chi}\) in order that the perturbed operator also belong to such a class. Abstract results are used in the study of initial-boundary value problems for a system of partial differential equations with several fractional Riemann–Liouville derivatives of different orders with respect to time and for an equation with a fractional Prabhakar derivative with respect to time.
Os Benefícios da inclusão paterna durante a assistência de enfermagem no pré-natal
Authors: Kristine Bispo dos Santos Michelle , Santos Souza Tuany
Published: May 2023

Esse estudo busca refletir sobre os benefícios da inclusão paterna durante a assistência de enfermagem no pré-natal. Trata-se de um estudo qualitativo, do tipo revisão narrativo, que foi realizado por intermédio de consultas e coleta de dados nos bancos, como a BVS e PUBMED. Segundo os critérios adotados, foram encontrados 25 artigos pertinentes à proposta, após leitura dos mesmos, as informações que corresponderam ao objetivo desse estudo foram discutidas nos resultados sob a forma de categorias. A valorização da paternidade nas consultas do pré-natal por profissionais de enfermagem desperta o homem a participar e acompanhar todo o processo de desenvolvimento do feto com a gestante, então, a participação ativa do pai facilitará o vinculo do trinômio pai/mãe e filho que fortalecerá o relacionamento familiar. Diante dessa perspectiva, é necessário um olhar do profissional de enfermagem durante a assistência pré-natal ao pai e suas necessidades durante a gravidez para que o homem se sinta integrado ao cuidado e atenção.
El aprendizaje activo como proceso de enseñanza-aprendizaje en el curso de física general de la UNAD
Authors: Ramírez Calderón Yudi Ester , Tique Escobar Diana Lorena
Published: May 2023

In the analysis processes that are carried out within the courses of the different programs of the UNAD, the behavior of the students is reviewed on issues related to the passing and dropout rates, seeking to design strategies to reduce the dropout and failure rate, which is highly representative in basic science courses. Among these courses is General Physics, which meets the conditions of analysis, being a large course, with students from different programs and where the indicators of approval and dropout presented are not the most appropriate. In this sense, this document presents the process that will be carried out to incorporate active learning in the teaching-learning process in the general physics course of the UNAD, through the use of a didactic strategy based on guides, which will allow students understand and approach the basic concepts of physics in a more attractive way that is directly associated with the real world and everyday life and with what is intended to positively impact the passing rate of the course.
Implementación del mooc fex del wp@e-lab en estudiantes de grado décimo en la I.E. Liceo Integrado Fray Francisco Chacón en Sopó, Cundinamarca
Authors: Torres Payoma Freddy Alexander , García Cruz Walter Loren
Published: May 2023

At present, virtual and distance learning spaces have been developed in the search for different alternatives in the construction of experimental environments, among which e-Learning spaces and massive open and online MOOC courses stand out. The COVID-19 health emergency reflected the need to implement academic interaction activities at a distance; therefore, the educational institutions opted for the virtual and distance modality for the development of the curricula and programmatic content addressed in each of the areas of knowledge. Simulation-based virtual laboratories are one of the resilient alternatives. On the other hand, school institutions in Colombia do not have the necessary infrastructure or the financial and technology capacity for the creation of scientific laboratories. The international project World Pendulum Alliance proposes the creation of virtual learning environments, reinforcing the experimental field through the implementation of remote laboratories. For this purpose, an alliance is created between different universities in Europe and Latin America, with the aim of disseminating remote experimentation in Basic Sciences. Among the consortium of partner universities, the Universidad Nacional Abierta y a Distancia - UNAD is linked to the project and, among its dissemination activities, has created the ReEx-SDC Science Dissemination Center, led by researchers from the School of Basic Sciences, Technology and Engineering ECBTI. This article shows the results obtained from the MOOC course of the IST of the University of Lisbon at the Fray Francisco Chacón School in tenth grade students, with the objective of including remote experimentation in the tenth grade physics curriculum in the following school year.
Tópicos de investigación de internet de las cosas en la cadena de suministro
Authors: Giraldo Castellanos José David , López Hernández Valeria , Castaño Gonzales Tania
Published: May 2023

In the context of Industry 4.0, there is a gradual adaptation of emerging technologies to business processes. Within this context, the objective is to identify and analyze the research topics of the publications that address the Internet of Things (IoT) in logistics and the supply chain; for which the Scopus database was consulted between 2009 and 2021, selecting the 50 documents with the highest number of citations, and then categorizing and analyzing them into three common thematic topics, identified according to their object of study: implementation of IoT in the chain supply and logistics; usefulness of the IoT and other emerging technologies; and IoT in the agricultural and food supply chain. The interest in investigating the benefits and challenges of IoT, and its applications in the industrial, automotive, retail, pharmaceutical, transportation, energy, medical care, marketing, reverse logistics, food, agricultural, footwear, textile and postal sectors is concluded. Articulated to technologies such as RFID, cloud computing, geopositioning, sensors, cyber-physical systems, telematics and mobile devices; for identification, communication and monitoring processes that improve real-time traceability between actors and objects in the chain, to have accurate information, reduce costs and be more efficient.
CMTM4 as a new partner for IL-17 receptor: adding a piece in the puzzle of IL17-driven diseases
Authors: Col Jessica Dal , Galdiero Maria Rosaria , Ciaglia Elena
Published: May 2023

IL-17 has emerged as an important cytokine in protecting the host from
mucosal infections, but also as a pathogenic determinant and therapeutic
target in numerous autoimmune and inflammatory diseases (e.g. psoriasis,
psoriatic arthritis and ankylosing spondylitis, inflammatory bowel
disease and multiple sclerosis) [(1)](#ref-0001). The IL-17 family
includes six members (IL-17A to IL-17F) that act through the IL-17
receptors [(1)](#ref-0001). The most studied IL-17A, as well as
IL-17F, binds to IL-17RA and IL-17RC resulting in heterodimerization.
Currently IL-17A, IL-17F, IL-17RA or IL-23, a cytokine produced by
innate immune cells that promotes expansion of Th17 cell populations,
are targetable by monoclonal antibodies (mAbs). These mAbs have been
approved for the treatment of different autoimmune diseases, most
notably psoriasis, where their efficacy has outperformed conventional
non-steroidal anti-inflammatory and tumor necrosis factor (TNF) blocking
drugs. However, clinical trials and real-life experience have shown an
increase in fungal and bacterial upper respiratory tract infections in
patients treated with mAbs that block IL-23/IL-17 signaling.
Accordingly, single nucleotide polymorphisms in genes encoding IL-17A,
IL-17RA, IL-17RC, IL-23, or NF-κB activator 1 (ACT1, an adapter protein
downstream of the IL-17R) which abrogate cellular responsiveness to
IL-17A, were associated with susceptibility to chronic mucocutaneous
candidiasis (CMC), a persistent infection of the skin, nails, and/or
mucous membranes with commensal Candida species
[(2)](#ref-0002). So new effective targeted approaches in IL-17
signaling are desirable. Knizkova and colleagues identified a new
adaptor molecule involved in the IL-17/IL-17R cascade
[(3)](#ref-0003). Through murine and human cell models, the authors
found that CMTM4 (CKLF Like MARVEL Transmembrane Domain Containing 4)
constitutively bound to the subunit IL-17RC becoming integral part of
the IL-17R signaling complex (IL-17RSC) upon IL-17A stimulation. CMTM4
promoted the surface expression of IL-17RC by regulating
posttranslational modifications, especially IL-17RC glycosylation and
trafficking to trans-Golgi up to plasma membrane. CMTM4 was required for
the recruitment of adapter ACT1, for the activation of p38, JNK and
transcription of genes encoding proinflammatory cytokines upon IL-17A
stimulation (Figure 1A). Keratinocytes from the tail of Cmtm4−/−
mice specifically express lower levels of IL-17RC respect to
Cmtm4 mice (Figure 1B). In vivo, when
imiquimod (IMQ) was applied on the ears or shaven backs of
Cmtm4 mice, they developed less severe
psoriatic lesions and lower local expression of IL-17A target genes
compared to Cmtm4 mice (Figure 1C).
Impact of Riverbank erosion on Riverine Dwellers along Bhagirathi-Hoogly River, West Bengal, India
Authors: Deb Himika , Deore Sachin
Published: May 2023

Riverbank erosion is the burning issue of riverine dwellers as
well as in our society. Due to this erosion people are suffered in many
problems such as land loss, property loss and monetary loss. In many
cases, people are forced to leave their houses. Part of Nadia District
along Bhagirathi-Hoogly River is selected as a study area. The study
area comprises two blocks Ranaghat I and Chakdah. Among all households
hundred households are selected as samples. Primary data collected from
riverine dwellers is analysed in view to study the socio- economic
problems of riverine dwellers. Maximum peoples are suffered due to land
loss problem in the study area. So, we should have many steps to reduced
the rate of erosion. Govt. should take many measures to protect the
people of riverside also.