bluuebunny/crossref_metadata_2025 huggingface dataset:
Desempeño de corderos corriedale y cruza faenados a los 5 meses de edad: 2. Medidas en el Longissimus dorsi y en el espesor de grasa subcutánea en el animal vivo y su relación con el grado de terminación y la conformación carnicera en la canal
Authors: Bianchi G. , Garibotto G. , Caravia V. , Castells D. , Cassareto A. , Bentancur O.
Published: February 2024

El espesor de grasa subcutánea (EGS) y la superficie del músculo Longissimus dorsi (área del ojo del bife: AOB) se determinaron por ultrasonografía en 520 corderos hembras y machos enteros (32.04 ±5.4 kg y 141.5 ±30.9 días de edad), producto del cruzamiento de ovejas Corriedale con 21 carneros de las razas Corriedale (C), Texel (TX), Hampshire Down (HD), Southdown (SD), lle de France (IF) y Milchschaf (MF). Los cruzamientos con IF presentaron los valores más altos en EGS, en tanto que aquellos con MF los más bajos (7.1 vs 4.8 mm, P≤0.01, respectivamente). Los registros de AOB fueron superiores en los animales cruza (P≤0.01), particularmente cuando los padres utilizados provenían de razas carniceras (1303, 1289, 1281, 1266 mm2 vs 1225 mm2, P≤0.01, TX, SD, IF, HD y C; respectivamente). Se encontró una asociación positiva (P≤0.0001) entre EGS, estado ,corporal (EC), espesor de los tejidos en el punto GR (GR) y la escala empleada para tipificar las canales por cobertura de grasa (ETCG). Las correlaciones fueron medias a altas entre EGS, EC y GR y bajas con ETCG La correlación entre AOB estimada por ultrasonografía y medida en la canal fue positiva media (r=0.5; P=0.0001). A su vez se encontraron correlaciones medias entre esta última medida y la proporción de cortes valiosos (r=0.66; P≤0.0001) o la escala empleada para tipificar las canales por conformación carnicera (r=0.55; P≤0.0001).
Ultrasound Examination of the Orbit in Patients With Thyroid- Associated Orbitopathy – Examination Guide and Recommendations for Everyday Practice. A Review
Authors: Karhanová Marta , Čivrný Jakub , Kalitová Jana , Schovánek Jan , Malušková Miroslava , Hrevuš Michal , Schreiberová Zuzana
Published: February 2024

The purpose of this study is to present the possibilities and benefits of ultrasonography (US) of the orbit in the diagnosis and treatment of thyroid-associated orbitopathy (TAO).

Methods: US examination of the orbit is an essential addition to clinical and laboratory examination in TAO patients. Nevertheless, it is often neglected in clinical practice or indicated with delay. Based on previously published studies and our experience with the diagnosis and treatment of TAO patients, we aim to highlight the clear benefit of US examination of the orbit and oculomotor muscles, not only for correct TAO diagnosis but also in the monitoring of the disease over time. However, knowledge of the drawbacks and limitations of this method is also essential, as we shall point out. It is always necessary to remember that US examination must be evaluated in connection with the clinical findings. A detailed recommendation for US examination of the extraocular muscles and the orbit based on our experiences with diagnosing and treating TAO patients in daily practice is also included.

Conclusion: According to our experience, US examination of the orbit is an excellent and irreplaceable tool for timely TAO diagnosis and further disease monitoring. However, considerable examiner experience and detailed knowledge of the clinical and ultrasound manifestations of TAO are essential.
Pars Plana Vitrectomy in the Treatment of Rhegmatogenous Retinal Detachment
Authors: Chrapek Oldřich , Matušková Veronika , Vysloužilová Daniela , Beránek Jan , Souček Jan , Sičová Kristína , Březík Michal
Published: February 2024

Aim: The aim of the study is to retrospectively evaluate the anatomical success rate and functional results of 25G+ PPV in the treatment of newly diagnosed rhegmatogenous retinal detachment (RRD).

Material and Methods: The set consists of 152 eyes of 152 patients, of which 71 (47%) were men, average age 54 years, operated on by one surgeon for RRD at the Eye Clinic of the University Hospital and Medical Faculty of Masaryk University Brno from 1.7.2019 to 4.5.2021 using the 25G+ PPV technique. 25G+ PPV with pre-equatorial cerclage was performed on 7 patients. The patients' anamnesis included blunt ocular trauma and uncomplicated cataract surgery with implantation of a posterior chamber intraocular lens. The cause of RRD was retinal tear/s, regardless of their number and location. The transparency of the anterior segment of the eye enabled reliable visualization of the posterior segment. Preoperative proliferative vitreoretinopathy (PVR) grade A-D2 was admissible. Patients with a history of penetrating ocular trauma were excluded. The postoperative findings and functional outcomes of the patients were evaluated 1–3 months after PPV. The operation was anatomically successful if the retina was fully attached. Final visual acuity (VA) was evaluated for each patient. The final visual acuity examination was carried out typically on a Snellen optotype, either without correction, with the patient’s own spectacle correction or with correction according to the current values on the autorefractometer. The arithmetic average was used for the numerical expression of the attained results, and the numerical values were also expressed in percentages. Since the different groups were not compared with each other, no statistical test was necessary to analyze the results.

Results: In 150 (98.7%) of the 152 patients in the group, we achieved complete retinal reattachment, in 2 (1.3%) patients the retina remained detached, and we recorded anatomical failure of the treatment. Fifty (33%) patients achieved VA ≥ 4/8.

Conclusion: In 133 (87.5%) patients, we are able to state anatomical success even without the presence of intraocular tamponade in the operated eye. These patients can be considered completely cured. 25G+ PPV has demonstrated its contribution to resolving RRD.
Crowdfunding as a Strategy for the Convergence of Digital and Traditional Forms of Marketing
Authors: Chernukhin V. S.
Published: February 2024

The purpose. To reveal the potential of using crowdfunding for marketing purposes. The paper considers the concept of crowdfunding, the history of its emergence, the formation of its modern model as a result of digitalization, describes the modern model of crowdfunding and identifies the benefits that startups get from using it as a marketing strategy. Result. It was revealed that the use of crowdfunding as a marketing strategy provides startups with a number of advantages due to the synergistic effect that achieved due to the convergence within crowdfunding of digital and traditional forms of marketing.
Innovation is a way forward
Authors: ZAINOL ZAINI
Published: February 2024

The case study highlights the obstacles faced by supply chain management (SCM) cycle in the automotive industry, which are caused by various factors including human inconsistency. The industry operates in a dynamic ecosystem where customer preferences constantly change, necessitating a more reliable and less human-dependent approach to enhance market response. As the government advocates for Industry 4.0 to embrace technology and reduce dependence on intensive labor, innovative solutions like Robot Processing Automation (RPA) offer a potential remedy.
Rahman’s Quest with the BanglaMarket: Triumph or Tragedy?
Authors: Toyon Mohammad Abu Sayed
Published: February 2024

This case study explores the journey of Rahman, an aspiring entrepreneur, as he navigates the complex landscape of e-commerce in Bangladesh. Rahman’s vision is to create ‘BanglaMarket’ an e-commerce platform that not only competes with established players but also addresses unique market niches and supports local businesses. The case is systematically constructed, relying on a wealth of information learned from public sources and in-depth interviews with Rahman. The case delves into key strategic decisions Rahman faces, including market analysis, customer engagement, technology investment, and competitive differentiation. Students will examine Rahman’s entrepreneurial journey, analyse market dynamics, and formulate a comprehensive marketing strategy. The case is designed for undergraduate students, offering valuable insights into entrepreneurship, e-commerce, and the challenges and opportunities presented by the dynamic Bangladeshi market. Through this case, students will enhance their critical thinking, analytical, and communication skills while unravelling the complexities of launching and managing an e-commerce business in Bangladesh.
Changing a major
Authors: Fakhruddin Muhammad Farhan , Ismail Yusof
Published: February 2024

Pursuing a degree programme of one’s childhood dream and blessed by one’s parents could not guarantee that the person will be able to complete his studies. The case walks the readers through the experience of Hasan who completed his matriculation studies and enrolled into MBBS (medical) programme of a public university in Malaysia. Hasan realized that there was a misfit between his aptitude and the nature of medical studies when he was in his second year. The case chronicled Hasan’s actions and reactions in coping with his poor academic performance, fulfilment of his parents’ wish, his lack of concentration and inability to digest his courses, changing to another academic discipline with his current university, or withdrawing from his university and making a new application to other public and private universities. There are compelling lessons that students, instructors, university authorities and parents could generate and contemplate after going through Hassan academic adventure.
Las palabras clave se agitan con el viento: explorando la dinámica de uso de descriptores temáticos en El País para las noticias sobre “amnistía” durante 25 años
Authors:   Universidad de Murcia, Saorín-Pérez Tomás , Pastor-Sánchez Juan-Antonio ,   Universidad de Murcia
Published: February 2024

This work is a preliminary exploration into how the use of keywords related to "amnesty" in the newspaper El País has evolved over 25 years. Instead of utilizing the full text in natural language, it begins with the thematic indexing of news provided by the media itself in the form of keywords assigned from its controlled vocabulary. A conventional exploration of the data raises numerous questions about the interest of controlled languages in journalistic documentation and how they can serve as data for research in digital humanities and information science, offering a new perspective on the construction of meanings and the analysis of the change in use and sense of terms.
Hemólise em amostras sanguíneas
Authors: Stumm Mayara Cristina , Black Falcão Sodré , Vuicik Felipe Luiz Marques , Melo Ana Júlia Pereira de , Dos Santos Eduarda Dalmolin , Korpalski Pâmela Maran , Giordani Thainá Simões , Braz Paulo Henrique
Published: February 2024

Hemolysis is one of the interfering factors that can limit the results of various biochemical tests, and this study aimed to assess the interference of hemolysis in the reliability of biochemical tests conducted in clinical-surgical procedures in the veterinary hospital routine. The methodology was retrospective, based on the analysis of records of animals treated at the Veterinary Hospital Unit (SUHVU) of the Federal University of Fronteira, Campus Realeza (Paraná) from January of 2020 to December of 2022. The tests conducted in the Veterinary Clinical Analysis laboratory included serum determination of total proteins, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), creatinine and urea. Based on the biochemical results, animals were divided into three groups according to the degree of hemolysis observed in the serum: mild hemolysis (HD); moderate hemolysis (HM) and intense hemolysis (HI). The control group (GC) was determined based on reference values specific to the species. Data were tabulated in spreadsheets and analyzed using Pearson's correlation test (p). Mild hemolysis was predominant and, in dogs, did not affect the analyzed biochemical values in comparison to the reference averages for the species, regardless of the degree. Isolated, most measurements increased. In cats, changes were more significant concerning the group average, with ALP showing the greatest variation, not consistent with the elevation of hemolysis. None of the parameters had a strong correlation of interference between hemolyses, only moderate negative and positive correlations in ALP and urea.
ONTOLOGIES OF PROCESSES OF INTELLIGENT MANAGEMENT OF THE PRODUCTION OF ENTOMOPHAGES
Authors: Chernova I. , Lysenko V.
Published: February 2024

The article deals with the ontologies of processes of intelligent management of the production of entomophages for biological protection of plants based on the application of the results of own research regarding the development and implementation in this production of i data mining based on neural networks, fuzzy logic, semantic modeling, cognitive and correlation-regression analysis.

The purpose of the work – increasing the efficiency the processes of management of the production of entomophages.

The object of study is the process of structuring knowledge regarding the processes of intelligent management of the production of entomophages.

Methods of research – ontological approach, system analysis, results of own research, software environment Visual Understanding.

Ontologies of processes have been developed: intelligent management of entomophages production, intelligent decision-making support in production management, use of artificial intelligence methods in production management; the ontology of knowledge in the processes of intelligent decision-making support in production management, the meta-ontology of the processes of intelligent production management. The destinations of the ontologies, as well as the formalization of the meta-ontology of the processes of intelligent management of the production of entomophages, are presented.

The results of the research are the basis for the creation of intelligent decision support systems, provide the integration of knowledge regarding the processes of managing the production of entomophages.
REMOTE MONITORING OF MINES IN FIELDS WITH USING NEURAL NETWORKS
Authors: Opryshko O. , Pasichnyk N. , Shvorov S. , Kiktev N. , Dudnyk A. , Sovych V.
Published: February 2024

The work is devoted to the issue of humanitarian demining of agricultural lands. The difference between humanitarian demining and military demining is the lack of strict deadlines for the implementation of measures, as well as relatively small human and technical resources and large areas of monitoring. The situation is particularly difficult on marginal lands, which are poorly monitored by the local population and, accordingly, the establishment of minefields may be unexpected for farmers. Marginal lands are a potential source of energy raw materials for bioenergy, the importance of which is increasing in the modern conditions of the destruction of traditional logistics chains of supply of energy resources. The purpose of the work was to develop a method of express monitoring regarding the presence of mines in the fields. Operational research of large areas is possible precisely thanks to remote monitoring technologies, in particular thermal imaging. The hypothesis about the possibility of identifying mines due to the difference in the dynamics of heating and cooling of explosive objects under solar radiation during the day was tested. The research was conducted on the basis of the training ground of the military department of the National Academy of Sciences of Ukraine. TM-62M anti-tank mines, high-explosive shells caliber 125 mm, etc. were studied. When setting up the experiment, part of the ammunition was buried in the soil to a depth of 2-5 cm in accordance with the instructions for demining.

It was established that only sunny days are suitable for thermal imaging monitoring, and samples installed in the shade were not identified. The maximum temperature difference for mines was recorded in the morning, and for massive shells in the evening. With regard to buried mines and projectiles, during thermal imaging monitoring, only depressions and bumps on the site were recorded. Based on the low selectivity of thermal imaging monitoring, neural networks were used to indicate mechanically laid mines on the ground. Positive results were obtained.
WIRELESS SYSTEM FOR MONITORING MICROCLIMATE PARAMETERS BASED ON ARDUINO HARDWARE
Authors: Rezvin E. , Lendiel T.
Published: February 2024

Production and energy use of biogas is one of the important sectors of renewable energy sources.

The process of obtaining biogas is affected by a number of factors: the temperature of the process, the quality of raw materials, the acidity of the fermentation medium, and others.

The purpose of the study is to develop a subsystem for monitoring technological parameters for the bioenergy complex, where wireless transmission of measured data can be provided.

A subsystem for monitoring technological parameters for the bioenergy complex has been implemented. The development was carried out on the basis of a complex of Arduino technical tools and provided for wireless transmission of measured data to the operator's display. The calculation of the distance at which the monitoring subsystem can work to create a connection for wireless data transmission has been performed. The software and hardware of the specified monitoring subsystem are presented.

Free space attenuation and data transmission range were calculated to be 73.35 dB and 46.294 m, respectively. Testing was carried out in laboratory conditions.
Penerapan Teknologi IoT Pada Tanaman Hidroponik Untuk Monitoring Pertumbuhan Tanaman di Desa Puccadi
Authors: Heri Adi , Insani Chairi Nur , Irianti Arnita , Rasyid Nurdina
Published: February 2024

Pengembangan teknologi sangat dibutuhkan untuk sistem pembangunan yang lebih baik. Teknologi dapat memberikan perubahan-perubahan dasar bagi masyarakat, terutama dalam konteks peningkatan kualitas hidup dalam masyarakat. Pada umumnya metode hidroponik yang dilakukan dengan menggunakan media air, dimana kondisi air yang perlu diperhatikan adalah pasokan air, oksigen, nutrisi, pH dan Intensitas Cahaya. Sinar lampu UV pengganti sinar matahari yang dapat membantu kebutuhan tanaman untuk proses fotosintesis yang menghasilkan zat makanan seperti karbohidrat sehingga tanaman lebih cepat tumbuh. Dari analisis situasi diketahui sebagian besar masyarakat di Desa Puccadi.Budidaya tanaman dengan sistem hidroponik pada skala rumah tangga dengan memanfatkan perkarangan atau halaman memiliki potensi yang cukup besar. Bedasarkan latar belakang tersebut, maka dilaksanakan pelatihan dan pendampingan hidroponik berbasis IoT kepada masyarakat Desa Puccadi Kecamatan Luyo. Kegiatan pengabdian ini diterapkan dalam bentuk pelatihan dan pendampingan dengan tujuan peserta dapat secara langsung mempraktikkan peenerapan IoT pada tanaman hidroponik untuk memonitoring tanaman. Kesimpulan dari kegiatan pelatihan hidroponik berbasis IoT di Desa Puccadi Kecamatan Luyo sebagai yaitu pelaksanaan pelatihan dan pendampingan hidroponik berbasis IoT berjalan dengan baik dan dapat memberikan pengetahuan terkait penerapan teknologi iot kepada masyarakat desa Puccadi Kecamatan Luyo.
Transformasi Digital dalam Peningkatan Manajemen Aktivitas Panti Asuhan Al-Mabrur Bekasi Berbasis Sistem Informasi
Authors: Andy Achmad Hendharsetiawan  , Aida Fitriyani  , Rakhmi Khalida  , Rafika Sari  , Ramdhania Khairunnisa Fadhilla
Published: February 2024

Teknologi informasi yang terus berkembang di berbagai sektor kehidupan menuntut para pihak yang terlibat agar dapat beradaptasi dengan teknologi. Upaya adaptasi teknologi juga terus dikembangkan oleh pengelola Panti Asuhan Al-Mabrur Bekasi. Suatu transformasi digital yang dilakukan oleh Panti Asuhan Al-Mabrur dalam rangka meningkatkan manajemen aktivitas siswa dengan menggunakan sistem informasi. Panti asuhan, sebagai tempat bagi anak-anak yang membutuhkan perlindungan dan perawatan, memerlukan pendekatan yang terorganisir dan efisien dalam memantau serta meningkatkan kualitas kehidupan sehari-hari anak-anak tersebut. Pelatihan ini bertujuan untuk memberikan pemahaman kepada pengelola panti asuhan dan siswa mengenai penggunaan sistem informasi, untuk mempermudah dalam mendata partisipasi siswa dalam setiap kegiatan yang diadakan oleh Panti Asuhan Al-Mabrur. Dengan adanya sistem informasi yang terintegrasi, panti asuhan dapat menciptakan lingkungan yang lebih adaptif terhadap teknologi dan responsive terhadap berbagai aktifitas di Panti. Luaran dari kegiatan pengabdian kepada masyarakat ini yaitu siswa dapat melihat dan mengakses data aktivitas secara mudah, serta pengelola panti asuhan dapat memiliki rekapitulasi data digital untuk memantau dan mengevaluasi kegiatan para siswa.
Pelatihan Desain Foto Produk UMKM Menggunakan Aplikasi Canva Pada PKK Papan Mas Bekasi
Authors: Sofica Verra , Fauzi Ahmad , Mukhayaroh Anna , Fakhriza Muhammad Hilman
Published: February 2024

Kegiatan pengabdian masyarakat di PKK RW 007 Kecamatan Tambun Selatan bertujuan untuk memberikan pemahaman dan keterampilan kepada anggota PKK terkait pemanfaatan aplikasi Canva dalam desain foto produk UMKM. Fokusnya adalah pada PKK RW 007 Papan Mas Tambun Selatan di Kota Bekasi.Peserta kegiatan diberikan pelatihan praktis dalam menggunakan aplikasi Canva, sebuah platform desain grafis yang user-friendly. Dalam pelatihan ini, anggota PKK diajarkan cara menciptakan desain foto produk yang menarik dan mendukung promosi UMKM. Melalui aplikasi Canva, mereka dapat dengan mudah mengedit gambar, menambahkan teks, dan membuat desain yang estetis tanpa memerlukan keahlian desain grafis yang mendalam.Penggunaan Canva bertujuan untuk memberdayakan UMKM di PKK RW 007 agar dapat meningkatkan daya saing produk mereka di pasar. Dengan desain yang menarik, produk UMKM dapat lebih mudah dikenali dan diminati oleh konsumen. Selain itu, pelatihan ini juga memberikan pemahaman mengenai strategi pemasaran melalui media sosial dan platform online, sehingga produk UMKM dapat dijangkau oleh pasar yang lebih luas. Hasil dari kegiatan ini diharapkan memberikan dampak positif, seperti peningkatan penjualan dan kesadaran masyarakat terhadap produk UMKM PKK RW 007. Selain itu, kegiatan ini juga dapat menjadi modal sosial bagi anggota PKK untuk terus mengembangkan keterampilan dalam pemanfaatan teknologi dalam mendukung pengembangan UMKM di lingkungan mereka.
Examining Educational Quality in Public and Private Secondary Schools of Gujranwala: A Comparative Study
Authors: Rasool Shafqat , Alvi Asma Anis , Sheikh Ayesha
Published: February 2024

This study critically assesses the educational standards in both public and private schools in Gujranwala, focusing on key aspects such as physical infrastructure, teacher competence, and the financial framework. The primary objective is to conduct a comprehensive examination of the physical facilities in both sectors, identifying potential differences that may impact the overall educational experience. Additionally, the study aims to compare the qualifications and capabilities of teachers, detecting variations in teaching quality between public and private schools. The financial aspects, including fee structures and compensation systems, are also scrutinized to gain insights into the economic dimensions of education in each sector. This research offers valuable insights into the current state of education in Gujranwala, serving as an informative resource for educational policymakers, parents, and the broader community. The findings aim to provide evidence-based decision-making, facilitating potential improvements in education quality and addressing any existing disparities between public and private schools.
Parental Involvement and Academic Motivation in Early Years: A Quantitative Analysis
Authors: Naeem Scherezade , Khan Najmunnisa
Published: February 2024

Early Childhood Care and Education (ECCE) aims to develop a child's social, emotional, cognitive, and physical needs integrally in order to lay a strong base for everlasting learning and positive transformation of students. The objective was to find out the relationship between early-year parental involvement and academic motivation along with the impact between these two variables. The researcher also sought to find out the moderating effect of the educational level of parents on the relationship between early-year parental involvement and academic motivation. The researcher applied a quantitative methodology and the correlational data analysis reflected a strong, impactful and significant relationship. The moderating test results showed that the educational level of parents has a positive moderating effect. It is recommended that parental counselling and parental educational programs should be implemented in Pakistan so that parents can upgrade their education and enlighten their minds to nurture and support early-year pupils.
English Language Anxiety: Investigating the Effect on Primary School Teachers' Performance
Authors: Afzal Ashfaq , Ali Muhammad Shahid Zulfiqar , Asghar Suneeta
Published: February 2024

This study has been conducted by the researcher under a positivist paradigm while opting for the Quantitative approach. The study has been conducted while including 230 ESTs purposively and included in the study. All of the selected teachers were serving in FGEI's (C/G) Lahore region. The teachers' perspectives regarding their anxiety were measured with the help of a questionnaire comprising 30 items adopted from (Horwitz et al., 1986). On the other hand, the concerning teachers’ terminal GPA in English taken from the BISE results was taken to measure their performance. The results revealed an inverse and weaker effect of the teachers’ anxiety on their performance.
Exploring Content-Related Difficulties Faced by Student-teachers of B.Ed Programme in Learning 'Derivation' Concept at Sukkur IBA University
Authors: Solangi Ghulam Mohuyddin , Rind Amjad Ali , Mughal Shahid Hussain
Published: February 2024

This study explores student-teacher content-related difficulties in learning the "Derivation" concept in B.Ed. Program of Sukkur IBA University. The qualitative study used exploratory research design and purposive sampling for data collection. Data was collected through interviews and thematically analysed. The study found that most students struggle with derivation, including building a basic concept, understanding the logic behind the definition, differentiating function and variable in Leibniz Notation, understanding word problem words, deriving information from word problems, and choosing an appropriate technique to solve word problems. Most students struggle to understand limited concepts. The current study suggested that student-teachers should be taught by changing teaching methodology from procedural to conceptual, teaching the pre-concept of the main concept, connecting mathematical concepts with real life, and using a problem-solving approach to learn derivation.
Impact of Teachers' Motivation on Students' Performance
Authors: Nahid Shagufta , Muzaffar Noshaba , Abbas Muhammad
Published: February 2024

The main goal of this research was to analyze the impact of the motivation of teachers on the academic achievement of students. For the current study, twenty secondary school teachers from the Faisalabad region participated in structured interviews to collect qualitative data. The interview questions stated that a 20 to 30-minute interview period was to be anticipated. The responses were recorded before being turned into text. Teachers contend that a number of interconnected environmental factors influence their motivation, dedication, passion, and commitment to their line of work. The influence of teacher excitement on student involvement and participation cannot be overstated, say many educators. The influence of teacher excitement on student involvement and participation cannot be overstated, say many educators. Motivated teachers can create a stimulating learning environment that fosters students' enthusiasm for learning and internal motivation. The study's findings suggest that teachers should use a range of incentive tactics to raise student performance.
Laser interstitial thermal therapy as a radiation-sparing approach for central nervous system tumors in children with cancer predisposition syndromes: report of a child with Li-Fraumeni syndrome. Illustrative case
Authors: Guadix Sergio W , Pandey Abhinav , Gundlach Carson , Walsh Michael , Moss Nelson S , Souweidane Mark M
Published: February 2024

BACKGROUND

Ionizing radiation and alkylating chemotherapies increase secondary malignancy risk in patients with cancer predisposition syndromes (CPSs), such as Li-Fraumeni syndrome. Laser interstitial thermal therapy (LITT) is a minimally invasive ablation technique that has not been associated with mutagenic risks. We describe the case of a child with LFS and a history of treated choroid plexus carcinoma (CPC) who developed a second primary glial tumor that was safely treated with magnetic resonance imaging (MRI)–guided LITT.

OBSERVATIONS

A 4-year-old male with left parietal World Health Organization grade III CPC associated with a TP53 germline mutation was evaluated. The patient underwent neoadjuvant platinum-based chemotherapy before near-total resection, followed by 131I-8H9 immunotherapy and 30 fractions of 54-Gy proton radiotherapy. He remained without evidence of disease for 2 years before developing a slow-growing mass adjacent to the left frontal ventricular horn. Stereotactic biopsy revealed a glial neoplasm. Given the nonsuperficial location and focality of the lesion, MRI-guided LITT was performed for ablative therapy. There were no complications, and 2 years of surveillance revealed continued retraction of the ablated tumor focus and no subsequent disease.

LESSONS

Alternatives to mutagenic therapies for brain tumors should be explored for patients with CPS. LITT paired with imaging surveillance is a logical strategy to ensure durable outcomes and mitigate treatment-related secondary neoplasms.
Management of a recurrent spinal arachnoid cyst presenting as arachnoiditis in the setting of spontaneous spinal subarachnoid hemorrhage: illustrative case
Authors: Hussain Omar , Treffy Randall , Reecher Hope M , DeGroot Andrew L , Palmer Peter , Bakhaidar Mohamad , Shabani Saman
Published: February 2024

BACKGROUND

Spontaneous spinal subarachnoid hemorrhage is a rare pathological entity with a variety of presentations depending on the underlying etiology, which often remains cryptogenic. The literature is sparse regarding the most efficacious treatment or management option, and there is no consensus on follow-up time or modalities. Additionally, there are very few reports that include operative videos, which is provided herein.

OBSERVATIONS

The authors present a case of spontaneous spinal subarachnoid hemorrhage without an underlying etiology in a patient with progressive myelopathy, back pain, and lower-extremity paresthesias. She presented to our institution, and because of progressive worsening of her symptoms and the development of compressive arachnoid cysts, she underwent thoracic laminectomies for evacuation of subdural fluid, fenestration of the arachnoid cysts, and lysis of significant arachnoid adhesions. Her clinical course was further complicated by the recurrence of worsening myelopathy and the development of a large compressive arachnoid cyst with further arachnoiditis. The patient underwent repeat surgical intervention for cyst decompression with an improvement in symptoms.

LESSONS

This case highlights the importance of long-term follow-up for these complicated cases with an emphasis on repeat magnetic resonance imaging. Unfortunately, surgical intervention is associated with short-term relief of the symptoms and no significant nonoperative management is available for these patients.
Impacto del estrés laboral en los profesionales de enfermería que otorgan cuidados hospitalarios
Authors: Jiménez Hurtado William , Fonseca Lizeth Navas
Published: February 2024

Introducción: Uno de los factores como la carga horaria laboral excesiva en los profesionales de enfermería, resulta un riesgo para la salud profesional con probable afección en la calidad y productividad del servicio brindado. Objetivo: Determinar el impacto del estrés laboral en los profesionales de enfermería contratados a medio tiempo en la Universidad Técnica de Ambato. Metodología: Se realizó un estudio descriptivo, no experimental transversal. Se aplicó una encuesta con la Escala de estresores laborales versión española Nursing Stress Scale (NSS), durante el mes de julio de 2023. Se incluyó a todo el personal de enfermería que labora medio tiempo en la Universidad Técnica de Ambato como docentes de práctica hospitalaria (n=50). Se consideraron datos como edad y servicio de labores hospitalarias. Se excluyó al personal de enfermería de tiempo completo. Para determinación de la frecuencia y porcentaje del estrés laboral. Resultados: Los profesionales de enfermería encuestados predominaron en los servicios como Quirófano 18 % (n=9), Emergencia 12 % (n=6), Neonatología 12 % (n=6) y Cirugía Hospitalización 10 % (n=5), con una edad promedio de 38,6 años (Min 24 – Max 59). La determinación del estrés laboral según los estresores evaluados predominó el puntaje caracterizado como “alguna vez” con el 54 % (n=27), seguido del puntaje “nunca” con el 26 % (n=13), puntaje “frecuentemente” con el 16 % (n=8) y finalmente el puntaje “muy frecuentemente” con el 4 % (n=2). Conclusión: El estresor sobre el desacuerdo con el tratamiento de un paciente se relacionó y causo mayor impacto en el estrés laboral de los profesionales de enfermería.
Medicina 5P (personalizada, predictiva, preventiva, participativa y poblacional): Un nuevo paradigma en salud pública y prevención
Authors: Navarrete Chávez Grace
Published: February 2024

A lo largo de la historia, en el ámbito sanitario se han evidenciado grandes avances científicos y tecnológicos en el diagnóstico y tratamiento de enfermedades. La medicina tradicional y sus modelos asistenciales se han centrado de manera fundamental en los procesos curativos, sin embargo, en los últimos años nace una nueva concepción de la medicina a partir de los avances en genética molecular, vigilancia genómica, bioinformática así como el uso de Big Data.1 Características homogéneas y, aunque se lograron grandes beneficios sanitario.
Lik Krste Frankopana u anonimnom talijanskom epu Savorgnanide
Authors: Jusup Magazin Andrijana
Published: February 2024

U fondu rukopisa Znanstvene knjižnice u Zadru čuva se ep na talijanskom jeziku nepoznatog autora iz druge polovine 18. stoljeća, koji na naslovnici uz generički naslov Poema, u nastavku predlaže mogući naslov Savorgnanide. Autor kronološkim redoslijedom prikazuje višestoljetni uspon obitelji Savorgnan posvećujući više pjesničkog prostora njezinim najmoćnijim članovima. Jedan od njih je Girolamo Savorgnan (1466. – 1529.), zahvaljujući istaknutoj ulozi u mletačkoj obrani Furlanije u ratu Cambraiske lige. U tom se ratu vojnom vještinom, s druge strane, u vojsci cara Maksimilijana Habsburškog, proslavio Krsto Frankopan (oko 1482. – 1527.). U radu seanalizira ideološka uvjetovanost prikaza i funkcija Krstina lika u epskoj heroizaciji člana obitelji Savorgnan. Pjesnik ističe Krstinu vojnu vještinu kako bi uveličao Girolamovu pobjedu. Međutim, pripisuje mu prijetvornost, lakomost i nepromišljenost kojima suprotstavlja Girolamovu iskrenost, velikodušnost i strpljivost. Zahvaljujući antitetičkom odnosu ovih likova, autor zadovoljava jedno od glavnih obilježja epa: pripovijedanje o sukobu dviju zajednica, pri čemu junak, autor i čitatelj dijele isti, u ovom slučajufilovenecijanski ideologem.
Okolnosni sekundarni predikati u dativu
Authors: Krsnik Davor
Published: February 2024

Tema rada su sekundarni predikati obilježeni dativom. Svrha rada je pokazati da su konstrukcije sa sekundarnim predikatima u dativu relevantne za raspravu o kriterijima podjele između deskriptiva ili deskriptivnih sekundarnih predikata i restriktora, odnosno sekundarnih predikata s okolnosnim značenjima kao što su uzročnost, uvjetnost i dopusnost. Pokazuje se da se sekundarni predikati u dativu tipično rabe kao restriktori. U rečenici se ostvaruju kao parenteze s odjelitim propozicijskim sadržajem. Tipično sejavljaju na preverbalnom položaju i gotovo se isključivo ostvaruju s pridjevima fizioloških, psihofizioloških i mentalnih stanja nad kojima referenti nemaju kontrolu ili ju gube. Oslanjanjem na korpusnu analizu i opis semantičkih okvira preispituje se gledište da su sekundarni predikati u dativu čimbenici u uzročno-posljedičnim obrascima, tipično čimbenici racionalizacije načina na koje referenti postupaju ili načina na koje doživljavaju stvari u situacijama nad kojima nemaju ili gube kontrolu. Dolazi se do zaključka da se ostvarenje restriktivne funkcije sekundarnih predikata u dativu može predvidjeti prema semantičkoj ulozi referenata o kojima se prediciraju. Restriktivna funkcija u pravilu će se uvijek ostvariti kada referent ima ulogu doživljavača.
Development of Innovative Activity of University Teachers: Philosophical and Psychological Perspectives
Authors: Gut Yu. N. , Tursunov L. E. , Lanskikh M. V. , Akhmedova Sh. B.
Published: February 2024

In the era of the development of innovative technologies, the processes taking place in universities determine new requirements for the personality and professional competence of a teacher. A modern teacher is not just a transmitter of information and accumulated experience, but also a person who understands the essence of modern life and strives to harmoniously fit into existing realities, while focused on changing his consciousness, worldview and openness to everything new. In this connection, the problem of the teacher’s psychological readiness for innovation, as a component of his professionalism, is relevant. The purpose of the study: to study the peculiarities of readiness for innovation and identify the main barriers preventing the development of innovations among university teachers; based on the results obtained, to develop a methodology for the development of innovative activity of teachers. The study involved 156 university teachers aged 27 to 40 years with 1 to 15 years of work experience at the university. The study revealed that about a third of teachers show a low level of readiness for innovation. Only 22% of teachers have a high level of innovation activity. In the structure of readiness for innovation, they will have a motivational component, indicating a desire for success in achieving their goals. It was also found that the leading factors hindering the innovative activity of teachers are: insufficient awareness of possible innovative activities at the university; the belief that only the traditional education system is effective; lack of assistance in mastering innovations in the team, as well as fear of negative performance results. The systematization of the theoretical and empirical data obtained made it possible to develop a methodology for the development of innovative activity of university teachers, consisting of two main directions: environmental – features of the scientific and educational innovative environment; subjective – motivation, level of training and personal characteristics of teachers.
Promoting the Patriotic Agenda on Social Media among Russian Students
Authors: Parma R. V.
Published: February 2024

The study aims to compare patriotic attitudes among the social group of student youth, as reflected in public opinion dynamics and social media information flows. The research methodology was based on cognitive and network approaches to examining social processes. The methods of open sociological and statistical data analysis, cognitive content mapping and automated social media analysis were used to determine the content and intensity of the impact of opposing patriotic and anti-patriotic information flows in the Russian segment of social media on the social values and attitudes of student youth. The results of the study revealed a high intensity of information pressure of anti-patriotic information flow in the digital communications environment on the audience of student youth. The sociological data indicates a strong prevalence of patriotic attitudes among the youth, however, analysis of information flows reveals the widespread presence of anti-patriotic narratives and discourses on social networks. The student communities of supporters of the patriotic idea differ from the opponents in that they are much more numerous, but much less active in producing and promoting semantic content in the social media space. The social media segment in Russia lacks a well-developed network infrastructure, including opinion leaders and effective platforms for broadcasting patriotic content. The empirical study of information flows has shown that universities are not on the list of platforms for promoting the patriotic agenda. Russian universities face a significant challenge in implementing patriotic education for the youth due to their technological and ideological detachment from students who are immersed in the digital communication environment. These circumstances reveal institutional issues with implementing the state policy of youth development in the face of existential challenges.
Higher Education Internationalisation in Kazakhstan (2022-2023): Course Continuity or Change in the Focus?
Authors: Pogorelskaya A. M. , Troitskiy E. F. , Pakulin V. S.
Published: February 2024

The research aim is to evaluate the changes in Kazakhstan policy of higher education internationalisation due to the international relations transformation since February 2022. The research tasks are to identify the peculiarities of higher education internationalisation in Kazakhstan and to detect its main trends before and after 2022. Based on the definitions of higher education internationalisation formulated by J. Knight, P.G. Altbach et al., authors outline relatively successful attempts of Kazakhstan to follow world trends in higher education. However, research literature analysis suggests that there are still many problems in Kazakhstan higher education the Government is still unable to overcome due to the lack of resources.The authors confidently analyse the legal framework of higher education reform in Kazakhstan and decisively use event-analysis to identify the key characteristics of higher education internationalisation in Kazakhstan since its independence, during 1991-2023. The conclusion was that the country has been on a course of internationalisation since the 1990s, but that until 2010 it had been a point-by-point process. At the same time, a model of importing higher education services, mainly from Russia, was spontaneously formed. Since 2010, the second stage of internationalisation has begun, characterised by a large borrowing of Western models and practices, although the Western direction of interaction in higher education complemented, but did not replace, the Russian one. In 2022, Kazakhstan made an accelerated transition to the third stage of internationalisation of higher education, characterised by distancing itself from Russia, combining imports and ambitions to export higher education, and increasing competition with Russia for applicants.
Necessity Was the Mother of Human Cultural Invention
Authors: Loeb Gerald
Published: February 2024

The unique intellectual capabilities of Homo sapiens are often attributed to positive, physical evolutionary developments such as increased cranial capacity, upright posture, dexterous hands and an articulate oropharynx, despite the occurrence of similar features in other species that have not developed such capabilities. Humans are also unique, however, in lacking or ignoring instincts that define the social structures and behaviors of other animals. Genetically determined behaviors evolved to improve effectiveness in exploiting specific environmental niches. In nonhuman species, social structures, food choices, mating behaviors, child-rearing, etc. are driven strongly by pheromones and hormones and their neuronal targets, whose physiology evolves very slowly. Humans can rapidly invade new environments because they invent rather than inherit such behaviors, which cumulatively we call a culture. The invention of niche-specific social behaviors enables cultural evolution, which would otherwise be limited by the inflexibility of instinctual behavior. Suppression of instincts makes the invention and learning of cultures necessary, which imposes both an opportunity and a burden on individuals and societies. Cultural evolution enables human societies to invent, promulgate, compete and evolve their social structures in a generation or two rather than the hundreds of generations required for significant genetic evolution. Novel cultures and their social structures may conflict, however, with residual instincts. Such conflicts and their resolution will continue to constrain and drive cultural evolution.
Non-dimensionalization of the Compressible Navier-Stokes Equation by Pressure Wavelength and Period revealing its Singularity
Authors: Wang Shisheng
Published: February 2024

Fluid particles oscillating in compressible fluid field will produce a pressure (density) wave. The wave propagates in the field by a finite speed – the wave speed of c. Any function where the x and t dependence is of the form (kx - \(\omega\)t) (or of the form f(x-ct) and g(x+ct)) represents a traveling wave of some shape. The x and t are no longer independent variables, rather, they are inter-dependent. They are related by the wave propagating speed of c through a dimensionless scalar function ̶ wave phase function of \(\phi(x,t) = kx \pm \omega t,\) where space and time are nondimensionalized by wavelength (wave number) and period (frequency). All the inertial observers perceive the same dimensionless wave phase function, \(\phi(x,t)\), at a given point in space and time if they have relative motions. If the wavelength and period are picked out as a measuring unit to quantify the length and time interval, the physical values of the length and time interval must be correspondingly enlarged or shortened for different initial frames, to ensure the wave phase function to be an invariant dimensionless scalar function. The classical compressible Navier-stokes equation contains pressure and density terms, if it is non-dimensionalized by the pressure wavelength and period in an inertial frame; the resulting equation contains a Reynolds number, where the wavelength is its scaling length. Its value will change following the fluid particle motion, relative to rest frame (Lab frame); The wavelength will be shorter (frequency will be higher) if the fluid particle flows toward an observer. The flow will blow up when the flow velocity approaches wave propagation velocity. Furthermore, it shows mass-energy equivalence can be expressed as \(pV = mc^{2}\) in the co-moving reference frame (rest frame).