bluuebunny/crossref_metadata_2025 huggingface dataset:
Taming the Huntington’s Disease Proteome: What Have We Learned?
Authors: Seeley Connor , Kegel-Gleason Kimberly B.
Published: May 2021

Mass spectrometry (MS) is a physical technique used to identify specific chemicals and molecules by precise analysis of their mass and charge; this technology has been adapted for biological sciences applications. Investigators have used MS to identify differential expressions of proteins in Huntington’s disease (HD), to discover Huntingtin (HTT) interacting proteins and to analyze HTT proteoforms. Using systems biology and computational approaches, data from MS screens have been leveraged to find differentially expressed pathways. This review summarizes the data from most of the MS studies done in the HD field in the last 20 years and compares it to the protein data reported before the use of MS technology. The MS results validate early findings in the field such as differential expression of PDE10a and DARPP-32 and identify new changes. We offer a perspective on the MS approach in HD, particularly for identification of disease pathways, the challenges in interpreting data across different studies, and its application to protein studies moving forward.
Network effect in shared supply chain platform value co-creation behavior in evolutionary game1
Authors: Zou Xiaohong , Chen Jinlong , Gao Shuanping
Published: May 2021

The shared supply chain model has provided new ideas for solving contradictions between supply and demand for large-scale standardized production by manufacturers and personalized demands of consumers. On the basis of a platform network effect perspective, this study constructs an evolutionary game model of value co-creation behavior for a shared supply chain platform and manufacturers, analyzes their evolutionary stable strategies, and uses numerical simulation analysis to further verify the model. The results revealed that the boundary condition for manufacturers to participate in value co-creation on a shared supply chain platform is that the net production cost of the manufacturers’ participation in the platform value co-creation must be less than that of nonparticipation. In addition, the boundary condition for the shared supply chain platform to actively participate in value co-creation is that the cost of the shared supply chain platform for active participation in value co-creation must be less than that of passive participation. Moreover, value co-creation behavior on the shared supply chain platform is a dynamic game interaction process between players with different benefit perceptions. Finally, the costs and benefits generated by the network effect can affect value co-creation on shared supply chain platforms.
Bayesian assessment of utility tunnel risk based on information sharing mechanism
Authors: Zhang Guodong , Shi Meixia
Published: May 2021

The main body of the utility tunnel is all kinds of pipelines, so the normal operation of the pipelines is very important for the operation benefit of the comprehensive utility tunnel; meanwhile, identifying the potential risks of the pipelines in time can reduce the losses caused by the uncertain risks to the comprehensive utility tunnel. This paper uses the Stackelberg game model to analyze the risk information sharing among utility tunnel institutions which concludes in utility tunnel company and pipeline company, which is helpful for understanding the decision-making process in the game and its equilibrium results can guide utility tunnel company’s decision-making behavior in seeking utility tunnel risk treatment. On this basis, this paper analyzes the potential disaster risk factors in the operation process of utility tunnel, and constructs the risk early warning model of integrated pipeline corridor based on Bayesian network. The results show that the potential disaster risk during the operation of utility tunnel is evaluated, and the overall risk probability level, the key path and key risk factors of the occurrence of disaster risk events are obtained.
A Kalman filtering fuzzy logic algorithm for recognition of lane departure
Authors: Ren Kai
Published: May 2021

In all kinds of traffic accidents, the unconscious departure of the vehicle from the lane is one of the most important reasons leading to the occurrence of these accidents. In view of the specific problem of lane departure, a lane departure decision-making method is established without calibration relying on the Kalman filtering fuzzy logic algorithm, according to the characteristics of expressway lanes, based on the machine vision and hearing fusion analysis of lane departure, integrating the extraction of the linear lane line model and the region of interest (ROI) in this paper to judge the degree of vehicle departure from the lane by integrating the slope values of the 2 lane lines in the road image. The results show that the system has good lane recognition capabilities and accurate departure decision-making capabilities, and meet the lane departure warning requirements in the expressway environment.
Galectin-3: A factotum in carcinogenesis bestowing an archery for prevention
Authors: Jeethy Ram T. , Lekshmi Asha , Somanathan Thara , Sujathan K.
Published: May 2021

Cancer metastasis and therapy resistance are the foremost hurdles in oncology at the moment. This review aims to pinpoint the functional aspects of a unique multifaceted glycosylated molecule in both intracellular and extracellular compartments of a cell namely galectin-3 along with its metastatic potential in different types of cancer. All materials reviewed here were collected through the search engines PubMed, Scopus, and Google scholar. Among the 15 galectins identified, the chimeric gal-3 plays an indispensable role in the differentiation, transformation, and multi-step process of tumor metastasis. It has been implicated in the molecular mechanisms that allow the cancer cells to survive in the intravascular milieu and promote tumor cell extravasation, ultimately leading to metastasis. Gal-3 has also been found to have a pivotal role in immune surveillance and pro-angiogenesis and several studies have pointed out the importance of gal-3 in establishing a resistant phenotype, particularly through the epithelial-mesenchymal transition process. Additionally, some recent findings suggest the use of gal-3 inhibitors in overcoming therapeutic resistance. All these reports suggest that the deregulation of these specific lectins at the cellular level could inhibit cancer progression and metastasis. A more systematic study of glycosylation in clinical samples along with the development of selective gal-3 antagonists inhibiting the activity of these molecules at the cellular level offers an innovative strategy for primary cancer prevention.
Biological risk assessment: A challenge for occupational safety and health practitioners during the COVID-19 (SARS-CoV-2) pandemic
Authors: Carvalhais Carlos , Querido Micaela , Pereira Cristiana C. , Santos Joana
Published: May 2021

BACKGROUND: The COVID-19 global pandemic brought several challenges to occupational safety and health practice. One of these is the need to (re)assess the occupational risks, particularly, biological risks. OBJECTIVE: The purpose of this work is to promote guidance to occupational safety and health practitioners when conducting a biological risk assessment in this context. METHODS: The main steps of the biological risk assessment are explained with some inputs regarding the novelty posed by SARS-CoV-2 and an example of a qualitative risk assessment method is presented. Also, its application to two different activities was exemplified. RESULTS: In both cases, the assessment considered that vulnerable workers were working from home or in medical leave. The results showed low or medium risk level for the assessed tasks. For medium risk level, additional controls are advised, such maintain social distancing, sanitize instruments/equipment before use, use proper and well-maintained PPE (when applicable), and promote awareness sessions to spread good practices at work. Employers must be aware of their obligations regarding biological risk assessment and OSH practitioners must be prepared to screen and link the abundance of scientific evidence generated following the outbreak, with the technical practice. CONCLUSIONS: This paper could be an important contribution to OSH practice since it highlights the need to (re)assess occupational risks, especially biological risk, to ensure a safe return to work, providing technical guidance.
The interactive process of negotiating workplace accommodations for employees with mental health conditions
Authors: Hossain Sabrina , Moll Sandra , Tompa Emile , Gewurtz Rebecca
Published: May 2021

BACKGROUND: Implementing workplace accommodations is an effective means of retaining employees with mental health conditions. However, the process is poorly understood and poorly documented. OBJECTIVE: The purpose of this research is to explore the interactive process of negotiating workplace accommodations from the perspective of employees with mental health conditions and workplace stakeholders. METHODS: We interviewed employees across Canada who self-identified as having a mental health condition requiring accommodations, and six stakeholders at various workplaces across Canada who are involved in providing accommodations. Data were analyzed using a qualitative descriptive approach to identify key themes. RESULTS: The findings highlight that the process of negotiating accommodations is non-linear, interactive, and political. The process is shaped by organizational and political factors and collaboration between stakeholders. CONCLUSIONS: The negotiation process is a combination of social, relational and political factors. Clear and accessible accommodation policies, workplace awareness and specific workplace training on how to implement accommodations are needed to optimize the accommodation process for all involved.
Vocational rehabilitation for young stroke survivors in Gauteng public healthcare: Occupational therapists’ perceptions1
Authors: Dreyer Greea , van Niekerk Matty
Published: May 2021

BACKGROUND: The prevalence of working-aged stroke survivors is increasing yearly. Stroke is an expensive disease, causing financial burden to the government, the family and caregivers of the patient, thus making it imperative for working-aged stroke survivors to work to remain financially independent. Survivors’ need to work necessitates occupational therapists to shift their focus from basic activities of daily living, to rehabilitating work. OBJECTIVES: This study aimed to determine the perceptions of occupational therapists working with younger stroke survivors in public hospitals and clinics in Gauteng South Africa, about rehabilitating working-aged stroke survivors’ work ability. METHODS: Ethical clearance was obtained. A qualitative research design was used to obtain narrative, descriptive data from six focus groups. Therapists from public healthcare settings, who had more than six months’ experience and had worked in neurological rehabilitation within the six months preceding the focus group, were invited to participate. Focus groups were audio recorded and transcribed. Inductive content analysis was used to identify themes and categories. RESULTS: Few participants are involved in rehabilitating younger stroke survivors’ work ability or facilitating return to work (RTW). The study identified perceived barriers and enablers to rendering OT services that meet working-aged stroke survivors’ needs. CONCLUSIONS: Despite enabling employment equity laws in South Africa, OTs working in the public sector appear to experience a sense of futility when trying to rehabilitate young stoke survivors to RTW. Fragmentation of the public sector and limited resources impede successful RTW for working-aged stroke survivors. Survivors’ employment status and motivation to RTW facilitated rehabilitating work ability.
Determining the usability and technology acceptance of a powered and automated cargo management system during ladder lifting tasks: A pilot study
Authors: Miguel Cruz Antonio , Murphy Jessica , Chohan Avneet Kaur , Liu Lili , Rios Rincon Adriana Maria
Published: May 2021

BACKGROUND: Evidence for the adoption and acceptance of assistive devices for ladder lifting tasks by workers is scarce. OBJECTIVE: This study aims to investigate the technology acceptance and usability of a powered and automated cargo management system (RazerLift®) used by workers who need to lift ladders as part of their daily duties, as compared to mechanical cargo management systems (traditional). METHODS: We used a one-way repeated measures design in this study. Our primary outcome variable was a usability performance measurement measured as time (in seconds) for unloading and loading ladders using both systems. Our secondary outcome was technology acceptance, measured using questionnaires with a 5-point Likert scale: “strongly disagree (1)” to “strongly agree (5)”. RESULTS: The participants conducted the combined unloading and loading time using the powered and automated system (RazerLift®) 20.85 seconds faster than the traditional system (p-value = 0.000, t-value (df) = –5.730 (6), d = 2.713). Overall, the RazerLift® system (mean = 44.28, SD 5.58) had a higher technology acceptance compared to the traditional system (mean = 30.00, SD 7.91), (p = 0.041, t-value (df) = 6.589 (6), d = 4.60). CONCLUSIONS: The RazerLift® was more time efficient compared with the traditional system, and (2) the RazerLift® was superior in terms of technology acceptance compared to the traditional system.
Perspectives of spinal health within the school setting in a South African rural region: A qualitative study
Authors: Louw Quinette , Kriel Réna Isabel , Brink Yolandi , van Niekerk Sjan-Mari , Tawa Nassib
Published: May 2021

BACKGROUND: Spinal pain is one of the leading causes of morbidity globally. There is an increase in the number of children and adolescents who experience spinal pain and the lifetime prevalence of adolescent spinal pain varies between countries. In Africa, one in two adolescents experiences spinal pain and the prevalence is increasing. OBJECTIVE: This study reports on the knowledge and perspectives of school-attending children, adolescents, teachers, and parents/guardians regarding spinal health. METHODS: We conducted a descriptive qualitative case study with an interpretative and phenomenological approach. Data coding, management and analysis was done using ATLAS.ti computer software. RESULTS: Ninety-three participants (66 women and 27 men) were enrolled in the study. The barriers associated with students’ spinal health were multifactorial, including low levels of physical activity, dangerous gameplay, sports risks, poor ergonomics, school bags, insufficient knowledge, and pregnancy risks. Participants proposed strategies to improve spinal health including the provision of students’ lockers, advice on appropriate school bag types, embedding spinal education in the curriculum, general advocacy for spinal health, and integration of technology in teaching and learning. CONCLUSION: There is a need for further engagement on school-based spinal health promotion programs that consider local socio-economic, educational, and cultural factors.
Implementation of the Swiss ordinance on maternity protection at work in companies in French-speaking Switzerland
Authors: Abderhalden-Zellweger Alessia , Probst Isabelle , Politis Mercier Maria-Pia , Zenoni Michela , Wild Pascal , Danuser Brigitta , Krief Peggy
Published: May 2021

BACKGROUND: Switzerland’s Ordinance on Maternity Protection at Work (OProMa) requires that companies take the necessary measures to ensure that pregnant employees can continue working without danger. OBJECTIVE: To investigate the extent of compliance with OProMa within companies in French-speaking Switzerland as well as factors which facilitate and obstruct the ordinance’s implementation. METHODS: A stratified random telephone survey of 202 companies from the healthcare and food industry was conducted. Descriptive and correlational statistics were calculated. Responses to open questions were analysed thematically. RESULTS: Only a minority of companies performed risk analyses or adapted employees’ workstations, as per the legislation. OProMa was implemented more effectively in larger companies than smaller ones, in public rather than private ones, in the healthcare sector rather than the food industry, and when the person responsible for the wellbeing of pregnant employees within the company had undergone specific training on the subject. Data extrapolation suggested that only 2% of pregnant employees in French-speaking Switzerland’s food industry and 12% in its healthcare sector are properly protected according to OProMa’s provisions. CONCLUSIONS: Maternity protection in French-speaking Switzerland’s companies urgently requires improvement. In addition to the apparent need for stronger incentives and for monitoring of companies, our findings indicate a need to provide them with resources to meet OProMa’s provisions.
Correlation between psychosocial work factors and the degree of stress
Authors: Živković Snežzana , Milenović Miodrag , Krstić Ivana Ilić , Veljković Milan
Published: May 2021

BACKGROUND: Psychosocial risks and work-related stress are one of the most complex, most significant and most challenging problems that organizations around the world are facing. Stress negatively affects all participants in the organization and significantly contributes to negative health consequences and economic outcomes. OBJECTIVE: With timely identification and adequate assessment of psychosocial risks, it is possible to create healthy workplaces and healthy organizations where employees are satisfied and motivated. The paper will present the results of the research of psychosocial risks on a large sample of respondents in the Republic of Serbia. METHODS: A questionnaire was distributed to 1,212 participants of which 1,140 answered all the questions asked. Data from the questionnaire were analyzed using multiple regression analysis, Kolmogorov-Smirnov test, Spearman’s correlation coefficient and Pearson’s chi-square test (χ2). RESULTS: The results of multiple regression analysis showed that all psychosocial risks taken together are statistically significantly (p < .001) and explain 24%of the variance of the criteria. CONCLUSIONS: Psychosocial risks identified as statistically significant predictors are Labor Demands, Interpersonal Relations, Lack of Support, Work Role and Job Uncertainty. All predictors are statistically significant predictors at the level.01.
A systematic review of biomechanical risk factors for the development of work-related musculoskeletal disorders in surgeons of the head and neck
Authors: Maxner Andrew , Gray Heather , Vijendren Ananth
Published: May 2021

BACKGROUND: Previous studies have shown high rates (47–72%) of self-reported work-related musculoskeletal disorders (WRMDs) in surgeons of the head and neck. Physical requirements in the workplace, individual factors (e.g. poor posture, obesity) and psychosocial factors have been identified as risk factors. Establishing biomechanical risk factors may help prevent further development of WRMDs in this population. OBJECTIVE: The purpose of this critical review was to source studies that identified the biomechanical risk factors for WRMDs in this surgical sub-specialty. METHODS: Searches were conducted of Medline, CINAHL, and AMED databases from 1980 until September 2018. RESULTS: A total of 182 article were identified. Exclusion criteria lead to 163 full-text articles being screened, generating a total of 6 articles for review. The aims of the included studies varied significantly. Surgeons spend the majority of operating time in static, asymmetrical positions. Surgical loupes/headlamps significantly increased cervical spine loading. Articulated surgical arm supports provided optimal ergonomic conditions. Performing surgical operations with the surgeon in standing or sitting had no effect on task performance or demand. Physical fatigue was also measured in both positions. CONCLUSIONS: A combination of equipment-based and patient/surgeon position-based factors predispose surgeons to biomechanical risk factors. Studies of greater methodological quality are required.
Moving toward an integrated prevention approach for mental health at work: Promoting workers’ involvement through concrete actions
Authors: Lecours Alexandra , St-Hilaire France , Daneau Patrice
Published: May 2021

BACKGROUND: Work-related mental health problems are a primary cause of disability and lead to the absence of 500,000 workers each week in Canada. There is a growing body of literature suggesting integrated approaches of prevention are necessary to improve mental health at work. The involvement of numerous stakeholders inclusive of government agents, employers, and workers is recommended. However, only minimal information is available to suggest actions workers may adopt toward an integrated approach of prevention to improve mental health at work. OBJECTIVE: The aim of the study was to identify behaviors workers may adopt to foster mental health at work. METHODS: Following a descriptive qualitative research design, semi-structured interviews were conducted with researchers, professionals, and workers. Data were analyzed using a template analysis strategy. RESULTS: A total of 49 concrete behaviors were identified, grouped into ten sub-themes, and three broad themes. These main themes identify those behaviors that appear to be useful throughout the prevention continuum: 1) adopting a reflexive practice, 2) acting for one’s own mental health, and 3) acting for mental health of others. CONCLUSIONS: In harmony with the integrated prevention approach, this study offers a framework to organize workers’ concrete actions contributing to mental health.
Low back pain-associated factors in female hospital-based personal care attendants
Authors: Chang Ku-Chou , Lee Hsuei-Chen , Yen Chu-Ling , Liao Yi-Han , Hung Jen-Wen , Wu Ching-Yi
Published: May 2021

BACKGROUND: Low back pain (LBP) is common in personal care attendants because this profession requires much physical work. Information about the prevalence of LBP and LBP-associated risk factors in this group is limited. OBJECTIVE This study aimed to investigate the 1-year prevalence of LBP and identify LBP-associated factors in female hospital-based personal care attendants. METHODS: Forty-seven female hospital-based personal care attendants were recruited. The Nordic Musculoskeletal Questionnaire was used to investigate the prevalence of LBP during the recent 12 months. Participants completed a personal traits and associated factors questionnaire. Physical fitness and the knowledge test of body mechanics were assessed. Multivariable logistic regression analysis was used to explore LBP-associated factors. RESULTS: The 1-year prevalence of LBP was 46.8%. The strongest LBP-associated risk factor was poor abdominal muscle endurance, followed by insufficient knowledge on the test of body mechanics and higher psychological stress. CONCLUSIONS: The results demonstrate that the prevalence of LBP in female hospital-based personal care attendants appears to be high. Preventive programs should be initiated to reduce LBP-associated risk factors, such as improving abdominal muscle endurance, providing education in the proper use of body mechanics, and providing psychological intervention services for female hospital-based personal care attendants.
New potato variety Siverskiy and some agrotechnological method of its cultivation
Authors: Evdokimova Zinaida , Balakina Svetlana , Kalashnik Marina
Published: May 2021

Abstract. The purpose of the research of this work was to assess the main economically significant traits of a new medium-ripening nematode-resistant potato variety Siverskiy according to the data of the State varietal plots of the Russian Federation and to study individual agrotechnical methods of its cultivation. Method of research. Testing, hybridization, assessments, determination of biochemical parameters, table qualities, analysis for resistance to pathogens were carried out in accordance with the methodological recommendations for the technology of the potato breeding process. Results. The Siverskiy variety has competitive characteristics and meets many requirements of potato producers and consumers. In terms of ripening, it belongs to the mid-season group, multi-tuber, the average marketable yield is 24.0–29.0 t/ha, the maximum – 48.1–52.7 t/ha. It has excellent taste, increased dry matter content, attractive tuber shape, resistance to quarantine objects, late blight of tubers, viruses, common scab. The results of testing the variety in contrasting soil and climatic conditions of the Northwestern and Central Black Earth regions of the Russian Federation indicate a wide rate of its response to environmental conditions. The optimal parameters of agrotechnical methods of the generally accepted cultivation technology were revealed, taking into account the biological characteristics of the variety, which contribute to the realization of its potential productivity: the density of plantings for food purposes is 55 thousand pcs/ha with the introduction of complete mineral fertilizer at a dose of N90P90K90. The efficiency of cultivation of the Siverskiy variety was established using wide-row technology (90 cm), which provided a yield of 52.7 t/ha, the average weight of a marketable tuber 102 g, marketability. Scientific novelty consists in the creation of a new variety Siverskiy (hybrid 3602/28), which has a high yield, resistance to the main most harmful pathogens, quarantine objects and the development of individual technological parameters for its cultivation.
La formación social de los hijos en la familia
Authors: Brugarola. S. I. Martín
Published: May 2021

.
Instituciones sociales modernas:
Authors: Granero S. J. Jesús María
Published: May 2021

.
Política familiar en Alemania
Authors: Gorosquieta, S.J. J.
Published: May 2021

.
Journalists' role conceptions in covering sexual violence post-Weinstein
Authors:   , Jaeckels Beck
Published: May 2021

Since the publication of The New York Times article on Harvey Weinstein, journalists across the United States have had to adapt to a new reporting climate as it has evolved under the influence of the #MeToo movement. This thesis explores the reporting, editing, and decision-making processes used by journalists when discussing incidents of sexual violence. The purpose of this study is to understand how journalists chose to discuss individuals issuing accusations, perpetrators, and misconduct and investigations and whether the unique conditions of the #MeToo movement and post-Weinstein period affected this thought and decision-making process. Twelve journalists took part in in-depth interviews discussing their experiences reporting on sexual violence. Based on their answers, journalistic roles were conceived and discussed specific to the coverage of this traumatic event.
Tasks of Voluntary Rescue Teams in Extreme Weather Situations
Authors: Teknős László
Published: May 2021

The occurrence of weather phenomena associated with extreme precipitation, temperatures and winds are not unusual in the history of meteorology in Hungary. However, in view of the characteristics of damages, it can be ascertained that they are usually witnessed at local (settlement) level; they damage the natural and built environment, jeopardise the safety of people and their financial resources.  This greatly burdens the human resources of forces designated to respond to these anomalies, also their deployments, logistics and  the management system of their equipment. The current Disaster Management Act created a resolution to this tension between  damage prevention, response and rescue by declaring the possibilities of involving the voluntarism of citizens in organised and  regulated frameworks. It means: in order to increase the country’s safety, central, territorial, later district and settlement-level  voluntary rescue organisations and teams may be established. These units, considering their capabilities, are able to effectively and  efficiently manage the impacts of anomalies due to the weather. In this publication, the author attempts to present Hungary’s  vulnerability due to weather extremities with the help of the disaster management classification of settlements, to analyse the  deployment possibilities of voluntary rescue organisations and rescue teams, taking into account their capabilities established in the  framework of the national classification system.
„Pénzért valódi értéket” elv alapú közbeszerzések
Authors: Erdei-Derschner Katalin
Published: May 2021

A hatékonyság, mint kulcsfontosságú fogalom, előtérbe kerülésével az állami szektorban mára már elvárás, hogy minden közpénzköltés megfeleljen a „pénzért valódi értéket” (value for money) elvnek, a verseny tisztasága, az átláthatóság, a nyilvánosság és a többi közbeszerzési alapelv mellett. Az Európai Parlament és Tanács 2014/24/EU irányelv hazai implementációnak köszönhetőena 2015-ben hatályba lépett közbeszerzésről szóló törvénybe is bekerült a legelőnyösebb ár-érték elve mint lehetséges bírálati szempont. Ezzel megalapozta a „pénzért értéket” elv alapú beszerzés lehetőségét hazánkban is. A bírálati szempont azonban csak egy része a teljes koncepciónak.A tanulmány célja, hogy a rendelkezésre álló iránymutatásokon keresztül bemutassa az elv sokrétűségét, a beszerzési gyakorlatba való átültetési lehetőségeit és korlátait is.
Political Communication and Influence Through Twitter
Authors: Seitkazin Ruslan
Published: May 2021

Politicians are now learning that along with advertising on conventional media, they need to invest in online applications in order to get the attention of voters, particularly the youths. Among various microblogging services, Twitter is an essential part of popular culture. Today, Twitter is widely utilised not only to distribute information, but also political views and opinions.Therefore, politicians have turned to social media, particularly to Twitter, as a new form of political communication. The article attempts to capture the ways of using the potential of Twitter in communication strategies. It argues that in some occasions, Twitter plays a specific role in allowing politicians to monitor current political affairs and to interact with people, but in others, it is often employed as a personal branding strategy and not only during the election campaigns. It concludes with an insight that sentiment may impact the political opinion-making process which may lead to electoral intervention.
Can Chiefs Be the Problem of Ghana's Democratic Political Space
Authors: Essel Emmanuel Abeku
Published: May 2021

The 1992 Constitution of Ghana gives unfettered privileges to chiefs and their roles with regard to customs and their usages in the country. A whole chapter in the constitution has been dedicated to the chieftaincy institution which clearly indicates their mandates with a caveat that they cannot actively take part in politics. This arrangement, not only makes them feel alienated from the dayto-day-political discourse of the nation, but also leaves them with a sense of loss of their former position. However, since the institution is revered and forms part of the cultural heritage of the country, comments from these chiefs have in most cases shaped the political discussions of the nation positively or negatively. This paper looks at three major statements by some chiefs, the controversies these statements generated and the conclusions drawn. The paper is a desk research and the researcher relied on secondary data.
The impact of corona crisis on the economies of major metropolitan areas
Authors: Polidi Т. Д. , Gershovich A. Y.
Published: May 2021

The article presents the results of an operational assessment of the impact of the COVID-19 crisis on the change in the gross urban product (GUP) in 17 metropolitan areas of Russia with a population of more than 1 million people in 2020. The goal of the authors was to try to answer the most actual questions nowadays (early 2021): how deep was the fall of the largest agglomerations economies in Russia and abroad; did the corona crisis have a more negative impact on the largest metropolitan areas then on the rest of the economy? In order to answer these questions, two main tasks were: 1) to assess GUP in 17 largest metropolitan areas of Russia; 2) to consider foreign estimates of the GUP in 2020. For foreign comparisons, the authors use the first published data on changes in GDP and gross urban/regional product in the United States, Canada and Australia. The assessment of GUP in this work is carried out through the assessment of the component of employee compensation and then the transition to the GUP indicator on the assumption that such a ratio of compensation of employees to GDP in a city equals the average of the said ratios for the 17 metropolitan areas. The assessment showed that the real GDP growth rates in 2020 were negative not in all metropolitan areas, and in most of them economic losses turned out to be less than those of the Russian economy as a whole.
Investigating the Influences of Starting Age on Pronunciation: a Comparative Study of Chinese Learners of English As a Second Language
Authors: Ji Fei
Published: May 2021

This study aims to test the validity of Critical Period Hypothesis (CPH) by investigating the influence of starting age on Chinese English learners’ pronunciation. The study compares the degree of foreign accent of native Chinese English learners with different starting ages in learning English, in an attempt to determine whether early Chinese English learners could outperform late ones in terms of English pronunciation when exposed to an English-speaking setting. Furthermore, this research also proposes to investigate other possible factors that affect Chinese English learners’ pronunciation. Participants were asked to provide spontaneous speech samples through semi-structured interviews conducted face-to-face or via Skype. In addition, an additional read-aloud task was required to ensure a more thorough and in-depth interpretation. The final results run counter to the Critical Period Hypothesis as there appeared to be late starters who also achieved native-like pronunciation, and there was no significant difference between early starters and late ones in terms of pronunciation. However, the study also yielded some results suggesting that greater efforts and stronger motivations were required for late starters in order to achieve the same pronunciation levels as early starters’, indicating that starting age can be a sensitive rather than critical factor for second language (L2) pronunciation acquisition.
Effect of fenbenzyl and fenbendazole on peroxide intensity oxidation of lipids in the blood of dogs in experimental toxocariasis
Authors: Stybel V. V. , Gutyj B. V. , Said W. S.
Published: May 2021

Toxocariasis is a chronic helminthic disease caused by the larval stages of the nematode Toxocara canis. The problem of toxocariasis is important for both humane and veterinary medicine. Therefore, the aim of the study was to investigate the effect of fenbenzyl and fenbendazole on the intensity of lipid peroxidation in the blood of dogs during experimental infestation with the pathogen toxocariasis. The experiments were performed on 18 dogs, two to four months of age, and three groups of six animals were formed in each: control and two experimental groups. Puppies of all groups were experimentally infected with the pathogen toxocariasis at a dose of 5.000 invasive T. canis eggs per kg of body weight. The control group of dogs was as untreated control. Puppies of the first experimental group were fed the drug “Fenbendazole” at a dose of 150 mg per 3 kg of animal weight once a day for three days in a single dose. Puppies of the second experimental group were fed the drug “Fenbenzyl” at a dose of 350 mg per 3 kg of animal weight once a day for three days. In the clinical manifestation of the disease, toxocariasis secretes metabolic products that promote the formation of large amounts of free radicals, which in turn enhance the initiation of lipid peroxidation processes. With the use of fenbendazole and fenbenzyl, a probable decrease in these products was found starting from the 15th day of the experiment. It should be noted that the lowest level of diene conjugates and TBA-active products was in the blood of dogs of the second experimental group at 25 and 30 days of the experiment. Inhibition of lipid peroxidation processes in the treatment of dogs with fenbenzyl is due to the activation in animals of metabolic processes involving enzymes, including antioxidant enzymes that catalyze the processes of peroxidation and phosphorylation, as well as enhancing erythropoietic function. On the 30th day of the experiment, the level of diene conjugates in the blood of the second experimental group was 0.29 ± 0.02 IU/ml, and TBA-active products – 25.2 ± 0.40 μmol/l.
Sexual cycle of cats and non-invasive diagnostic methods
Authors: Burlakova O. V. , Stefanyk V. Y.
Published: May 2021

Mostly all feral cats are listed in the IUCN International Red Book. This fact is caused by the negative impact of civilization on the ecosystem, including fauna. This trend applies equally to feral cats from the family Felidae (tigers, jaguars, leopards, snow leopards) and the family Felinae (caracal, serval, ocelot, etc.). The low population size of domestic species, namely lynx and forest cat in Ukraine, is alarming. The use of innovative biotechnological techniques in reproduction can have a positive effect on the conservation of endangered carnivorous species. These auxiliary methods are aimed at improving the technique of obtaining and cryopreservation of sperm, oocytes, in vitro fertilization, artificial insemination, embryo transplantation, as well as synchronization and regulation of the sexual cycle. This last element is key in ex situ conservation programs in zoos. Under physiological course, feline reproductive cycle is unique, as the physiology of the body as a whole. The wild cat family is the pinnacle of predator evolution. Today there are 39 species of this family in the world, including the domestic cat. Most feral cats are endangered. The main reasons for the decline in wild cat populations in the wild are habitat loss, fragmentation, human-animal conflict, and for some species, poaching for fur and medicine. Therefore, many scientists in the world face the issue of increasing reproductive capacity, improving methods of monitoring reproductive function and endocrine status, as different species of cats have significant differences in the sexual cycle. The main purpose of the work is to improve the reproductive properties in the reproduction of wild cats using non-invasive diagnostic methods. Reproduction is a key success factor, so understanding the basics of the reproduction function will help develop strategies to conserve and influence populations of different feline species.
Diagnóstico E Proposta De Intervenção E Prevenção Do Desempenho Profissional Dos Colaboradores De Uma Empresa: Estudo De Caso Metalúrgica Herfab
Authors: Santos Grazielly Lima dos , Belém Yaçanna Freitas , Oliveira Daniel Barroso de , Roberto José Carlos Alves
Published: May 2021

Atualmente, as empresas e organizações, estão cada vez mais investindo e se preocupando com o desempenho de suas equipes, pois isso influencia diretamente na produtividade e lucros obtidos. Por isso, as ferramentas de gestão devem ser adotadas como uma estratégia de estabelecer metas através do diagnóstico organizacional, tanto com o objetivo de prevenir falhas como reverter. Sendo assim, o investimento na capacitação contínua dos funcionários é essencial para melhorar o desempenho. O objetivo deste artigo é avaliar e diagnosticar o desempenho funcional dos setores da empresa estudada e propor a implementação de programas de treinamento e incentivo para melhorar a eficiência do trabalho dos funcionários. A metodologia utilizada no trabalho, quanto a natureza, foi a forma aplicada, quanto a seus meios, foi feito de forma qualitativa como estudo de caso, e seus fins, foram do tipo exploratório. De acordo com a pesquisa realizada, na primeira etapa do diagnóstico organizacional, constatou-se que a área de recursos humanos é a mais crítica, o que se deve à falta de treinamento e padrões estabelecidos nas funções dos colaboradores, bem como à falta de benefícios e planos de motivação. Por isso, a pesquisa se fundamenta na importância de avaliar o clima organizacional e assim poder traçar estratégias que gerem impactos positivos e em longo prazo a organização. Com o resultado obtido, foi proposto estratégias de treinamento e desenvolvimento para otimizar a produtividade e serviço da metalúrgica em objetivos específicos: descobrir por que os funcionários da empresa não estão entusiasmados, analisar como aumentar a produtividade do restaurante por meio de treinamento e propor incentivos e benefícios para os funcionários planejados. Através das ferramentas mencionadas, para obtenção de melhoria nos processos dos recursos humanos, espera-se que isso monitore as medidas de melhoria e implemente responsabilidades, aumentando a produtividade.
Proposta De Implementação De Estratégias Para Gestão Administrativa: Estudo De Caso Na Empresa SC Transportes
Authors: Santos Euler Ribeiro dos , Cordeiro Izabele da Silva , Lima Rita de Cássia Siqueira de , Roberto José Carlos Alves
Published: May 2021

A busca pela excelência nos resultados frente à complexidade que envolve o mercado competitivo demanda por ferramentas estratégicas de comunicação e motivação que auxiliem não só a gestão administrativa das grandes empresas na propagação do modelo de gestão organizacional, como também na superação de metas. Neste artigo propõe-se a utilização das ferramentas supracitadas no âmbito da empresa SC Transportes em Manaus – AM, bem como a compreensão dos benefícios decorrentes de sua implementação. Diante disso, os objetivos específicos traçados visam identificar as melhores práticas utilizadas na motivação e comunicação no âmbito interno das organizações, analisar quais dessas práticas se adequam na empresa estudada e, por fim, planejar ações para implementar as estratégias de gestão administrativa junto aos colaboradores. A metodologia utilizada baseou-se em aplicação de estudo de caso e embasamento por meio de pesquisa bibliográfica, configurando-se como quantitativa e qualitativa quanto a sua natureza, e exploratória e descritiva quanto ao seu objetivo. A proposição das ações interventivas se efetivou a partir da aplicação ferramenta da qualidade 5W2H, dentre as quais se destacam: a implantação de ferramentas de comunicação interna e o plano de comunicação organizacional a ser elaborado, a implantação da gestão orientada para resultados como modelo de gestão organizacional, implementação de programas e planos de incentivos e bonificação por resultados. Assim, infere-se que, o plano proposto contribuirá decisivamente como referência no tratamento da problemática.
O Processo Saúde Doença No Contexto Da Violência Contra A Mulher
Authors: Cortez Juliana Joyce De Oliveira Silva
Published: May 2021

O artigo em tela tem como meta refletir e compreender o processo de saúde – doença no cenário em que a mulher é vítima de violência. Mostra-se bastante relevante essa temática, uma vez que são inúmeras as notícias de violência doméstica, conforme levantamento realizado pela Fundação Perseu Abramo, no ano de 2001, o qual informa que a cada 15 segundos uma mulher é agredida no Brasil. Apesar de já existirem discussões acerca desse tema nas práticas de saúde pública, ainda há uma necessidade de ser mais abrangente nos debates e discussões. O método utilizado se deu através de pesquisa bibliográfica com abordagem qualitativa, por se valer de questões discursivas e por estudar fenômenos existentes que, necessariamente, nos remetem à interpretação realizada. Pode-se concluir que a violência contra a mulher é uma problemática na questão de Saúde Pública, porquanto, seja qualquer tipologia da violência, vai interferir significativamente nos aspectos de saúde, como o adoecimento físico e mental das mulheres que sofrem de violência, e que apesar dos avanços na esfera jurídica, em contrapartida, em outras áreas, precisa avançar, em razão de que a violência praticada contra as mulheres pode causar traumas emocionais e ferimentos físicos, com cicatrizes profundas na alma e corpo. Diante desse contexto, é visível a ineficiência na criação de políticas públicas de saúde voltadas para esse público-alvo, as quais têm sido negligenciadas por parte do poder público como problema de saúde pública.
O Aleitamento Materno
Authors: Carvalho Marcelo de Paula , Santos Lahis Mourão Teodora dos , Abilio Cínthia
Published: May 2021

O aleitamento materno é de extrema relevância no contexto de saúde e desenvolvimento do lactente. Por isso, os objetivos deste trabalho foram descrever como ocorre a apojadura e seu mecanismo fisiológico; entender os benefícios do aleitamento materno para o lactente; compreender o que é a pega correta e as consequências da má pega. Para isso, foi realizada uma revisão não sistemática da literatura a partir de artigos científicos e textos-base de livros didáticos. Desse modo, os principais resultados a serem destacados são os papéis de diversos hormônios na apojadura; a extrema importância nutricional, de desenvolvimento e imunológico do leite materno; e, por fim, a pega correta como facilitadora da amamentação.
ABOUT DYNAMIC CIRCADE LIGHTING
Authors: Nasarenko L. , Suvorova K. , Bilyk E.
Published: May 2021

The issues of light non-visual influence on the human body during the work of office workers and students of educational institutions are considered. The necessity of creating a high-quality lighting environment of educational premises and offices by means of the corresponding dynamic lighting scenario taking into account non-visual effects of visible light is substantiated. The necessity of light levels revision of on working surfaces taking into account circadian effects is shown. The rapid development and increasing growth of LED lighting, which allows to obtain dynamic light scenes, as well as progress in knowledge of physiological mechanisms that regulate circadian rhythms, and their relationship with light stimuli allows to implement really high quality artificial lighting. The light environment not only affects the visual characteristics, but also has a significant impact on people through the so-called non-visual effects or those that do not form images (BOZ-effects) - mood, vivacity, circadian rhythms and more. It is important to combine visual and non-visual requirements with innovative lighting systems. Circadian lighting should always be evaluated at eye level, in the typical location of human existence in a specific internal environment. The improved lighting scenario involves synchronizing the light with the activity and circadian rhythms of consumers over a 24-hour cycle. Lighting in the auditoriums of educational institutions should meet the necessary visual requirements and create comfort for pupils and students. Audience lighting can be more efficient than lighting dynamics or dynamic lighting levels and color temperature. Automatic lighting control, which depends on the dynamics of daylight and should usually be built into the smart installation of dynamic lighting, should be a must.