bluuebunny/crossref_metadata_2025 huggingface dataset:
İSTANBUL'UN KADIKÖY İLÇESİNDE YER ALAN BİRİNCİ ULUSAL MİMARLIK DÖNEMİ EĞİTİM YAPILARI ÜZERİNE BİR DEĞERLENDİRME
Authors: KOÇAK Kıvanç
Published: December 2022

Bu çalışmada Birinci Ulusal Mimarlık üslubuna ait olan ve İstanbul'un Kadıköy ilçesinde bulunan eğitim binalarını ele almak amaçlanmıştır. Örneklerin çeşitli özelliklerini belirterek, özgün özelliklerini vurgulamak ve dönemi içinde değerlendirmek çalışmanın ana hedefidir. Çalışmanın kapsamını Kadıköy'de konumlanmış olan 4 yapı oluşturur. Söz konusu yapıların her biri bâni, mimar, plan özellikleri, cephe özellikleri, süsleme özellikleri açısından incelenmiştir. İncelenen örneklerle ilgili bilgiler yayınlardan ve yerinde tespitlerle elde edilmiştir. Yapıların çeşitli özellikleri çalışmada analiz edilmiş ve ek bilgiler dipnotlarda verilmiştir. Araştırma sonunda elde edilen verilere göre plan şemaları dikdörtgen, L ve U biçimindedir. Söz konusu yapıların dış cephelerinde sivri kemerlerle basık kemerler yaygın olarak görülür. Girişler bir çıkmayla dışarı taşırılarak belirtilmiştir. Cephelerde pencerelerin üzerinde ve kat aralarında silmelere yer verilmiştir. Dış cephede süsleme unsuru olarak karosiman kaplamalar ve çiniler görülürken; iç mekanda ise yalnızca karosiman kaplamalara yer verilmiştir. İncelenen örneklerden ikisi Mimar Kemalettin'in eseridir. Buna ek olarak bir yapının da Mimar Yahya'nın eseri olabileceği değerlendirilmektedir.
THE AUDIENCE STRUGGLE BETWEEN TELEVISION, CINEMA, AND OTT PLATFORMS: THE CASE OF NETFLIX AND DISNEY+ IN TURKEY
Authors: OKUMUŞ M. Sami
Published: December 2022

This study examines the actions of Netflix and Disney+, two of the most popular global brands among the many OTT platforms that continue their broadcasts based on domestic and foreign companies with a significant number of users worldwide and especially in Turkey after 2016. In this regard, as a result of the breakthroughs, strategies, and subscription numbers between Netflix, which started broadcasting in Turkey in January 2016, and Disney+, which started broadcasting in June 2022, it is questioned which platform is the spotlight for what reason and to what extent, and the main reflection of this OTT structure on cinema and television is examined. As the trends towards digital entertainment on a global scale changed and gained momentum as of 2020, the revenues in this sector increased by 31% and reached 61.8 billion dollars. This corresponds to a 26% increase compared to 2019, and OTT platforms worldwide reached 1.1 billion online subscribers. In 2020, the revenues of these platforms increased by 32% compared to the previous year, reaching 24.7 billion dollars. Considering that only Netflix shares are traded on the stock exchange with a value of over $60 billion, the growth rates are seen. The extent and direction of the growth of Netflix, which has 220.67 million users by 2022, and Disney+, which has 221.1 million users, as the leading corporations in this sector is the main issue of this study. This study aims to conclude by discussing the position of OTT platforms in the world and Turkey, the systemic and global structuring of these platforms during the COVID-19 pandemic, and the findings on the similarities or differences between Netflix and Disney+ in Turkey, following the transformations of the compulsory or optional audience perspective in the media and entertainment sector in recent years. Although there are many news and academic studies on Netflix today, since this study is about Disney+, which is a relatively new platform, it is aimed at pioneer studies on this subject, which has not yet been addressed comprehensively.
DÖNÜŞTÜRÜLEN BİR KARAKTER OLARAK HAMLET: AKİ KAURİSMAKİ’NİN HAMLET UYARLAMASI
Authors: ARSLANTEPE Mehmet , ÖNAL Efe
Published: December 2022

Sinema, ortaya çıktığı yüzyıl dolayısıyla diğer sanat disiplinlerinden farklı olarak daha yeni bir anlatım aracı olmuştur. Bu yenilik sinema için bir dezavantaj yaratmasının aksine bütün disiplinlerin biçimlerini ve dillerini yeniden üretmesini sağlamıştır. Bu yeniden üretim sırasında sinema kendisine yeni bir dil oluşturmuştur. Bu dilin ortaya çıkışı anlatı biçimlerine yeni bir boyut getirmiştir. Anlatılara dahil olan karakter öğesi ve zaman/mekân öğesi dönüşüme uğramıştır. Uyarlama sineması, bu dönüşümü karşılaştırmalı olarak inceleyebilmek için önemli olmuştur. Bu makalenin inceleme konusunu oluşturan Fin yönetmen Aki Kaurismäki, yazılı dile ait eserlerden sinemaya yaptığı uyarlamalarla yazılı eserlerde var olan karakterleri günümüz dünyasında anlatmıştır. Hamlet uyarlaması ile izleyicinin zihnindeki var olan “Hamlet” imgesinden yararlanmıştır. Bu imgeleri kendi karakterleri haline getirmiştir. “Hamlet”, Shakespeare’in kurguladığı “Hamlet” değil, Kaurismäki’nin kurguladığı “Hamlet” olmuştur.
BİR ANLATI TÜRÜ OLARAK VİDEO OYUNLARI
Authors: ÖNCÜ Melda
Published: December 2022

Bilgisayar oyunları ilk olarak 1960'lı yıllarda yapılmaya başlanır. Ancak bilgisayar oyunlarının ticari hale gelmesi ve hızla yaygınlaşması 1970lerde gerçekleşir. 1990'larda internet ağlarının gelişmesi ile birlikte oyunlar çevrimiçi olarak da oynanabilir hale gelir. Günümüzde, hemen her konuda ve her yaşa hitap eden kurgusal ve kurgusal olmayan türde oyunlar bulmak mümkündür. Ve bilgisayar oyunları bilgisayar teknolojilerindeki her yeni gelişme ile birlikte, giderek gelişen derinleşen yapılar olarak varlığını sürdürmektedir. Bilgisayar oyunları bir anlatıyı aktarabilmek için pek çok farklı anlatı dilini bir arada kullanan yapılardır. Bu anlatı dilleri temel olarak, sözel ya da yazılı anlatılar, görseller, ses efektleri ve müzik'ten oluşur. Bunun yanı sıra tüm bu yapıyı birbirine bağlayan kodlama sistemlerinden temellenir. Bilgisayar oyunlarının anlatılarını diğer anlatı türlerinden ayıran en önemli özellikleri interaktif oluşlarından ve oyuncuya içine gömülme deneyimi sunmalarından kaynaklanır. Bu şekilde bilgisayar oyunu izleyiciye/oyuncuya hiçbir zaman bütünüyle bitmiş, tamamlanmış bir yapı sunmaz. Bunun yanı sıra, bir bilgisayar oyununda anlatının ortaya çıkabilmesi de oyuncunun varlığı ve hareketlerini gerektirmektedir. Bu makalede, bilgisayar oyunlarının anlatı yapısı incelenmiş, bu oyunların edebiyat, görsel sanatlar ve müzik gibi anlatı dillerini bir arada kullanan kendine özgü bir anlatı yapısının olduğu gözlenmiştir. Oyun anlatılarını incelemek için günümüzde zaman zaman sinema teorilerinden yararlanılmakta olsa da bu anlatılar ağırlıklı olarak metin kuramları açısından incelenmektedir. Ancak oyun anlatıları pek çok farklı anlatı dilini bir arada kendi anlatısını aktaracak şekilde bir araya getiren yapılar olduklarından dolayı, günümüzde, oyunları incelemek tüm bu anlatı dillerinin birlikteliğinden ortaya çıkan bütünsel yapıyı kavramayı gerektirmektedir. Bu tür bir inceleme ise pek çok disiplinin bir arada kullanılması gerekliliğinin yanı sıra, oyunu oynamayı ve oynama sürecini gözlemlemeyi de gerektiren karmaşık bir işleme dönüşmüştür.
THE EXAMINATION OF DOODLE ILLUSTRATION STUDIES BY BARTHES' SEMIOTIC ANALYSIS METHOD
Authors: KUM Özlem
Published: December 2022

Semiotics is a branch of science that includes the processes of examining, interpreting and re-interpreting signs with the system of "Signifier", "Signifier", "signified". In semiotic analysis, besides the direct messages, the messages that are wanted to be conveyed indirectly are revealed. In this article, it is aimed to examine 10 randomly selected Doodle illustrations from the Doodle archive of 2022 using Barthes' semiotic analysis method. Azah Aziz's birthday, Indonesian Independence Day, Japan's Mountain Day, Kimiko Tsumura's 120th birthday, India Independence Day, Doodle designed for “Google”, Seiki Kuroda's 156th birthday, Qixi Festival, Luisa de Medrano's 538th birthday, Singapore National Day illustration works are analyzed.

In the article, literature review was used to obtain theoretical information about Doodle illustration works, and Barthes' semiotic analysis method was used for the analysis of randomly selected Doodle illustration works.

While the Google company used to publish Doddles only for important days, today it has gone to design diversification in different categories; It includes designs in its corporate image for birthdays of famous people, holidays, festivals, special days of countries (independence day, mountain day, etc.), national days as animation and video content, not just visuals.

It has been concluded that the birthdays of famous people, independence days of countries, mountain days, festivals, national days are thematically analyzed in Doodle studies, which are analyzed semiotically. It is noteworthy that typographic arrangements are frequently used in Doodle works, and that typographies are deformed and adapted to the design in an integrated manner with the visual. It has been concluded that the use of color directly reflects the subject it deals with or the characteristics of the culture it represents, and that Doodle impersonates the theme in the context of technical and color use.
SONAT FORMUNUN TARİHİ SÜREÇ İÇİNDEKİ GELİŞİMİ: JOAQUIN RODRIGO PİYANO SONATI ANALİZİ
Authors: ÇAĞLAK EKER Tuğba , ŞENTÜRK Prof.dr.nezihe
Published: December 2022

Bu araştırmanın amacı Joaquín Rodrigo’nun Album Centanario Piano (Yüzyıllık Piyano Albümü) kitabında yer alan Cinco Sonatas de Castilla (Beş Kastilya Sonatı) olarak bilinen Sonata, Sonata en fa sostenido menor, Sonata en Re, Sonata como un Tiento, Sonata en La isimli piyano sonatlarının form ve armonik analizini yaparak piyano eğitimi repertuarına çalışma rehberi niteliğinde bir bilgi kaynağı olarak katkı sağlamaktır. Çalışmada sonatın ve sonat formunun tarihsel süreç içindeki gelişimi farklı örnekler üzerinden ele alınmış, ardından Rodrigo’nun piyano sonatları analiz edilmiştir. Sonuç olarak araştırmanın form analizi basamağında Rodrigo’nun sonatlarında sonat allegrosu, şarkı formu ve tiento biçimi ile neo-klasik yaklaşımının görüldüğü söylenebilir. Armonik analiz doğrultusunda Sonata Sonata en Re ve Sonata en La’nın Klasik dönem sonat allegrosu armonik yapısını yansıttığı; armonik çeşitliliğin görüldüğü Sonata en fa sostenido menor ve Sonata, como un Tiento’da ise bir 20. Yüzyıl bestecisi olarak Rodrigo’nun çağdaş stilini göstermiş olduğu belirtilebilir. Ulaşılan sonuçlardan hareketle, piyano derslerinde eser seçiminde Rodrigo’nun piyano eserlerine yer verilerek, bestecilik stilinin tanıtılması ve öğrencinin farklı kültürlere ilişkin bilgi sahibi olması; Rodrigo’nun Cinco Sonatas de Castilla eserindeki sonatları çalışacak veya öğrencilerine çalıştıracak piyano eğitimcilerinin araştırma kapsamında yer alan analizler doğrultusunda eserleri tanımaları önerilir.
La formulación de cargos: una institución del debido procedimiento administrativo sancionador Analysis of the institution of the formulation of charges in the sanctioning administrative procedure
Authors:   Pontificia Universidad Católica, Lepe Vergara Joaquín
Published: December 2022

Este artículo presenta una conceptualización y análisis de la institución de la formulación de cargos. Para ello, se analizan diversas regulaciones sectoriales, así como la jurisprudencia y la doctrina nacional y comparada. A través de esta investigación, es posible demostrar que la formulación de cargos es un acto administrativo de capital importancia en cuanto permite el ejercicio del derecho a defensa y del principio de contradictoriedad dentro de un procedimiento administrativo sancionador. A pesar de que no existe una ley común de procedimiento administrativo sancionador en Chile, es posible definir esta institución y establecer sus elementos configurativos.
Régimen jurídico de los álveos de corrientes de uso público y de aguas detenidas. Estudio de las playas de ríos y lagos en Chile
Authors: Guzmán Silva Sergio
Published: December 2022

Hay algunos temas en el mundo del Derecho que aparecen más como dogmas que como resultado del análisis jurídico. El tópico de la naturaleza jurídica pública de las playas de mar, ríos y lagos, es uno de ellos. En el presente trabajo intentaré determinarla en el caso de los últimos dos cuerpos acuáticos, realizando un repaso por la desperdigada normativa que los regula, y la escasa jurisprudencia que sobre ellas se pronuncia. Asimismo, explicaré la consecuencia publificadora de la declaración de navegabilidad de un lago, y como es que ella podría considerarse expropiatoria.
Ejecución satisfactoria e insatisfactoria de los Programas de Cumplimiento presentados en procedimientos sancionatorios ambientales
Authors: Alfaro González Maximiliano , Benavides Leiva Martín
Published: December 2022

El presente artículo tiene por objetivo analizar la declaración de la ejecución satisfactoria e insatisfactoria de los Programas de Cumplimiento ambiental por parte de la Superintendencia del Medio Ambiente, debido a los relevantes efectos que tiene aquella determinación dentro del procedimiento sancionatorio, siendo este instrumento el mecanismo de incentivo al cumplimiento ambiental de mayor uso por parte de los regulados. Para ello se revisará la normativa aplicable a los Programas de Cumplimiento y su finalidad, la facultad fiscalizadora de la Superintendencia del Medio Ambiente, algunos casos donde la autoridad ambiental declaró su ejecución insatisfactoria, los criterios jurisprudenciales a este respecto y la impugnabilidad del acto administrativo que se pronuncia sobre la ejecución de este instrumento. Finalmente, atendida la inexistencia de regulación legal y reglamentaria sobre criterios para determinar si un Programa de Cumplimiento fue ejecutado satisfactoria o insatisfactoriamente, se propondrán algunos criterios para su determinación de conformidad con la finalidad de este instrumento, consistente en la promoción del cumplimiento ambiental y la protección del medio ambiente.
Los Diablos Rojos de Víctor Jara: un análisis coreográfico y musical
Authors:   Pontificia Universidad Católica de Chile (Chile), Benavente Javiera , Party Daniel ,   Pontificia Universidad Católica de Chile (Chile)
Published: December 2022

Este artículo es un estudio de la propuesta artística de Los Diablos Rojos de Víctor Jara, una comparsa de danza-música formada en el año 2009 para homenajear al cantautor en el día de su funeral. Desde esa fecha, la comparsa participa en eventos anuales de conmemoración de los detenidos y ejecutados políticos de la dictadura militar y esporádicamente en otras manifestaciones sociales. Nuestro primer objetivo es explicar la apropiación y transformación que la comparsa hace de la figura del diablo suelto de la fiesta de La Tirana. Consideramos asuntos como vestimenta, coreografía, repertorio musical y roles de género. El segundo objetivo es analizar las propuestas coreográficas y musicales de los Diablos Rojos. A diferencia de aproximaciones desde las ciencias sociales, que tienden a estudiar estos fenómenos como actos de memorialización o activismo social, nuestro enfoque como investigadores de las artes pone al centro el hecho de que las y los responsables de la comparsa son artistas profesionales, con motivaciones, preocupaciones y objetivos artísticos. Para relevar este aspecto analizamos siete de las canciones de Víctor Jara que forman parte del repertorio de danza-música de la comparsa.
Agudeza y desconcierto en la voz de Chinoy
Authors:   Pontificia Universidad Católica de Valparaíso (Chile), Jordán González Laura
Published: December 2022

Este artículo examina las ideas sobre la identidad de género planteadas por la recepción de la “voz aguda” del cantautor Mauricio Castillo (Chinoy). Trata de evitar una asociación determinista entre cuerpo y sonido vocal, así como entre voz e identidad. Se propone complejizar el concepto de voz “aguda” analizando diversos rasgos sonoros y performativos que inciden en la percepción de una voz “desconcertante”, destacando el timbre vocal y otros ruidos. Estudiando fuentes orales, musicales y hemerográficas, este estudio describe la puesta en escena de una performance de vulnerabilidad, que hace audible el cuerpo del cantante, al tiempo que caracteriza las voces extravagantes. A partir de este caso, se exploran las implicaciones de la performance vocal para la configuración de masculinidades divergentes en el contexto de una escena musical independiente contemporánea en Chile.
Custos ocultos: estudo de caso em uma empresa familiar
Authors: Santos Thiago Antonio Cavalcanti Bizinco dos , Callado Antonio André Cunha
Published: December 2022

O objetivo deste artigo é estudar os custos ocultos estruturais existentes em uma empresa familiar distribuidora de água mineral, localizada na cidade do Recife-PE. Para a realização da pesquisa a metodologia utilizada teve caráter descritivo, qualitativo e documental, sendo elaborada por meio da realização de um estudo de caso. Foram analisadas as variáveis estruturais e a coleta de dados feita através de entrevista semiestruturada, sendo a análise realizada através da adaptação da matriz 5Q1C. A pesquisa constatou a existência de alguns custos ocultos, sendo o principal relacionado ao mau controle, devido à ausência de um monitoramento de horários claro e efetivo; além da identificação dos custos ocultos com absenteísmo e ociosidade. Sugeriu-se a empresa a adoção de um controle regular e efetivo de horários, objetivando o tratamento, redução e prevenção de ocorrências dos custos ocultos de mau controle, que, por conseguinte propiciará melhor e maior controle sobre os fatores geradores de custos com absenteísmo, assim como melhor monitoramento dos intervalos entre as entregas, buscando a mitigação dos custos com ociosidade.
Optimization of Process Parameters for L-Glutaminase Production by Pseudomonas Species ALG3
Authors: Okpalla J. , Dim L. O. , Onyekuru D. A. , Duru I. E. , Mba T. O.
Published: December 2022

The present study reports the optimization of process parameters for L-glutaminase production  by  Pseudomonas species ALG3. The L-glutaminase –producing bacterium had already been isolated from soil at a location within Chukwumemeka Odumegwu Ojukwu University, Uli in Anambra state. It was identified using cultural, biochemical and molecular characteristics. Optimization of L-glutaminase production was done by assessing the effect of various parameters using mineral salt medium contained in 250 ml flasks. The parameters included various bivalent metals, pH, surfactants, growth promoters, amino acids and fermentation time. The Results showed that the addition of FeSO4 stimulated optimum L-glutaminase yield of 38.36 U/ml by Pseudomonas species ALG3, while the least production was observed with MnSO4. Enhanced L-glutaminase yield of 30.73 U/ml was recorded at pH 8.0, while the lowest enzyme accumulation was observed at pH 9.0. The highest L-glutaminase accumulation of 82.25 U/ml was achieved with Tween 80, while the lowest yield was recorded with stearic acid. Urea, stimulated maximum L- Glutaminase yield of 43.82 U/ml, while minimum accumulation was observed with peptone. Proline stimulated highest L- glutaminase yield of 42.63U/ml, while the lowest yield was observed with tyrosine. Highest L- glutaminase yield (91.88 U/ml) was observed after 72h, the yield decreased thereafter. The results obtained in the study illustrated that the optimization of process parameters, increased appreciably the L-glutaminase yield of Pseudomonas species ALG3. This suggest that Pseudomonas species can be used for large scale production of L- glutaminase, which can offer great potential for applications in Medicine and food industry.
Calculation of Cohesive Energies of 3-D Bismuth Selenide (Bi2Se3) and Bismuth Antimony BiSb Topological Insulators: DFT Study
Authors: Hemba E. C. , Ikyumbur T. J. , Trisma E. A. , Gbaorun F. , Aungwa F.
Published: December 2022

The cohesive energies of 3-dimensional (3-D) topological insulators bismuth antimony (BiSb) and bismuth selenide (Bi2Se3) were calculated. The Fritz Haber Institute Ab-initio molecular simulations (FHI-aims) code was employed for this calculation.  The output files of the FHI-aims code were used during the computation and the total energies at each number of iterations for single free atoms and bulk were then calculated. The results from this work revealed that bismuth atom becomes stable at 3rd iteration meanwhile both selenium and antimony atoms gain stability at the 5th iteration. The results also showed that bismuth antimony acquire stability at the 3rd iteration and bismuth selenide gain stability at 9th iteration. This implies that among the free atoms studied in this work bismuth atom is more stable and for the bulk bismuth antimony is more stable. The cohesive energies of BiSb and Bi2Se3 were calculated using the optimized parameters. The results obtained from the calculation of the cohesive energies in this work were 1.02eV and 1.76eV for BiSb and Bi2Se3 respectively. This results compared reasonably well with experimental results and have little percentage errors of 1.30% for bismuth antimony and 29.55% for bismuth selenide. The deviation observed in this work may be due to the DFT calculation of the solid rather than the atoms themselves.
Allelopathic Effects of Some Fruit Plant Species with Weeds
Authors: Sachan M. S. , Michui P. , Mezhatsu R.
Published: December 2022

Aqueous extracts of seven fruit plant species viz., banana (Musa paradisiaca), Indian gooseberry (Phyllanthus emblica), jack fruit (Artocarpus heterophyllus), guava (Psidium guajava), mango (Mangifera indica), litchi (Litchi chinensis), wood apple ((Aegle marmelos) were tested for germination, radical and plumule growth of barnyard grass and green amaranth. The lowest germination percentage (9.5 and 14.4%), plumule (3.94 and 0.92 cm) and radicle length (0.825 and 0.495 cm) of barnyard grass and green amaranth seedlings were obtained in seed treated with wood apple aqueous extract due to presence of some toxic compounds or other inhibitory materials in the species. One of these plant extract which performed the best i.e. wood apple leaves extract has the potential for use as an alternative crop as a herbicide (protectants) against barnyard grass and green amaranth weed species.
Comparative Efficacy of Certain Chemicals and Biopesticides against Pod Borer, Helicoverpa armigera (Hubner) on Chickpea
Authors: Reddy Yarumreddy Sunil , Tayde Anoorag R.
Published: December 2022

The present field investigation was carried out in the Prayagraj district of Uttar Pradesh. The experiment was conducted in rabi 2021 -22 at Central Research Farm, SHUATS, Naini, Prayagraj. The field replicated in RBD with seven treatments and one control plot. To check the comparative efficacy of certain chemicals and biopesticides against pod borer, Helicoverpa armigera (Hubner) on chickpea. The result of the efficacy of treatments showed that both chemicals and Biopesticides are effective against pod borer even if they have slight percent larval reductions. The different chemicals and Biopesticide treatments reveal that the most effective population infestation of pod borer, was recorded in, Chlorantraniliprole (0.46) followed by Spinosad (0.80), Emamectin benzoate (01.13), NSKE (01.46), Beauveria bassiana (01.66), Metarhizium anisiopilae (02.00), Bacillus thurenginesis (02.26) and the highest population of Pod borer was found in Control T0 (5.2). In another parameter higher yield and benefit cost ratio was recorded in chlorantraniliprole (18.89 q/ha and 1:2.21) followed by Spinosad (17.30 q/ha and 1:2.18), Emamectin Benzoate (15.80 q/ha and 1:2.14), NSKE (14.90 q/ha and 1:1.88), Beauveria bassiana (13.50 q/ha and 1:2.01), Metarhizium anisiopilae (11.63 q/ha and 1:1.50), Bacillus thurenginesis (9.80 q/ha and 1:1.62) as compared to control (7.42 q/ha and 1:2.01).
Successful Surgical Treatment of Stage IVB Immature Teratoma Involving the Liver and Thoracic Cavity, With Combination Chemotherapy: A Case Report
Authors: Park Eun-Kyu , Song Sang Hwa , Koh Yang Seok
Published: December 2022

Introduction

Immature teratomas are very rare tumors, representing only 1% of ovarian cancers. Distant metastases to the liver effect late disease manifestation, rendering chemotherapy the only viable option.

Case presentation

Here, we report the successful surgical management of stage IVB immature teratoma after cisplatin-based chemotherapy. A 20-year-old woman presented with a huge abdominal palpable mass and dyspnea. Postoperative pathology confirmed immature teratoma with metastases to the liver, diaphragm, and thoracic cavity (stage IVB). The patient underwent right hemihepatectomy, diaphragm resection, thoracic mass resection, and diaphragm repair using aortic artificial graft. She did not receive postoperative adjuvant chemotherapy. After the complete surgical resection of the tumor, the patient had no recurrence during the 44-month follow-up period.

Conclusion

No established treatment modalities have been developed for further treatment, once the first-line combination chemotherapy achieves unfavorable results in stage IVB immature teratoma. Surgical resection may offer hope for excellent disease control in this dismal stage. To obtain best possible outcomes, coordinated care between oncologists and general surgeons is required.
Skin color and health care in the pandemic: population survey with women in BAGÉ-RS / Cor da pele e a assistência em saúde na pandemia: inquérito populacional com mulheres em BAGÉ-RS
Authors: Härter Jenifer , Ribeiro Trindade Liliane , Da Silva Ziani Jarbas , De Lima Herrera Andriele , Felipe Peres Rezer João , Payão da Cruz Pellegrini Debora
Published: December 2022

Objetivo: identificar o comportamento da demanda por serviços do sistema único de saúde durante a pandemia da COVID-19, a partir do perfil racial de mulheres em Bagé. Método: estudo transversal, de base populacional com quatro inquéritos seriados quinzenalmente, a qual foi entrevistada uma amostra representativa dos indivíduos da cidade de Bagé. Realizado de abril a junho de 2020. Resultados: foram 984 entrevistadas do sexo feminino. Evidenciou-se que a cor da pele pode determinar o perfil de saúde. Quanto a busca por um serviço de saúde nas duas semanas anteriores à entrevista as pardas se diferem das brancas, tendo maior procura por assistência em saúde. As unidades de atenção básica representaram o serviço de saúde mais prevalente em todos os grupos de cor da pele. Conclusão: no contexto estudado os serviços de atenção primária estavam disponíveis e foram utilizados por um grupo que frequentemente encontra barreiras no acesso à saúde.
Severe Cervicodynia in a Patient With Pustules on the Palms
Authors: Xia Cheng , Lv Yan
Published: December 2022

A 51-year-old man had severe neck pain and pustules on both hands. What is your diagnosis?
Multifold Fermions and Fermi Arcs Boosted Catalysis in Nanoporous Electride 12CaO·7Al2O3
Authors: Meng Weizhen , Zhang Xiaoming , Liu Ying , Dai Xuefang , Liu Guodong , Gu Yuantong , Kenny E. P. , Kou Liangzhi
Published: December 2022

Topological materials have been recently regarded as ideal catalysts for heterogeneous reactions due to their surface metallic states and high carrier mobility. However, the underlying relationship between their catalytic performance and topological states is under debate. It has been discovered that the electride 12CaO·7Al2O3 (C12A7:4e−) hosts multifold fermions and Fermi arcs on the (001) surface near the Fermi level due to the interstitial electrons. Through the comparison of catalytic performance under different doping and strain conditions, based on the hydrogen evolution process, it has been demonstrated that the excellent catalytic performance indeed originates from topological properties. A linear relationship between the length of Fermi arcs, and Gibbs free energy (ΔGH*) has been found, which not only provides the direct evidence to link the enhanced catalytic performance and surface Fermi arc states, but also fully clarifies the fundamental mechanism in topological catalysis.
Avoiding bias in artificial intelligence
Authors: Gudis David A. , McCoul Edward D. , Marino Michael J. , Patel Zara M.
Published: December 2022

Artificial intelligence (AI) is ubiquitous and expanding, and the healthcare industry has rapidly adopted AI and machine learning for numerous applications. It is essential to understand that AI is not immune to the biases that impact our clinical and academic work, and in fact may inadvertently amplify rather than reduce them. As we harness the power of AI, it is our obligation to our patients to ensure that we address these concerns. We must take responsibility for proactive stewardship to protect against bias, not only for new AI algorithms, but also for our research studies that may one day provide data for those algorithms.
An Atomically Precise Pyrazolate‐Protected Copper Nanocluster Exhibiting Exceptional Stability and Catalytic Activity
Authors: Wang Yu‐Mei , Lin Xiao‐Chun , Mo Kai‐Ming , Xie Mo , Huang Yong‐Liang , Ning Guo‐Hong , Li Dan
Published: December 2022

The synthesis of atomically precise copper nanoclusters (Cu‐NCs) with high chemical stability is a prerequisite for practical applications, yet still remains a long‐standing challenge. Herein, we have prepared a pyrazolate‐protected Cu‐NC (Cu8), which exhibited exceptional chemical stability either in solid‐state or in solution. The crystals of Cu8 are still suitable for single crystal X‐ray diffraction analysis even after being treated with boiling water, 8 wt % H2O2, high concentrated acid (1 M HCl) or saturated base (≈20 M KOH), respectively. More importantly, the structure of Cu8 in solution also remained intact toward oxygen, organic acid (100 eq. HOAc) or base (400 eq. dibutylamine) confirmed by 1H NMR and UV/Vis analysis. Taking advantage of high alkali‐resistant, Cu8 illustrates excellent catalytic activity for the synthesis of indolizines, and it can be reused for at least 10 cycles without losing catalytic performance.
β‐Ketoenamine‐Linked Covalent Organic Framework with Co Intercalation: Improved Lithium‐Storage Properties and Mechanism for High‐Performance Lithium‐Organic Batteries
Authors: Wang Han , Zou Wentao , Liu Chao , Sun Yi , Xu Yi , Sun Weiwei , Wang Yong
Published: December 2022

As a new kind of crystalline porous polymers, covalent organic frameworks (COFs) exhibit great potential as electrode materials for rechargeable metal‐ion batteries due to their stable and adjustable structure, high porosity and abundant electrochemical active centers. In this paper, facile one‐step synthesis process is proposed to obtain the cobalt ion intercalated two‐dimensional β‐ketoenamine‐linked COF (Co−DAAQ−TFP‐COF, denoted as Co‐COF). The intercalation of Co ion in adjacent two layered structure of COF via coordination effects can activate the Li+ storage ability of aromatic ring in the original COF, greatly improve the utilization of redox active sites, shorten the migration length of electrons and ions, and promote fast lithium reaction kinetics. Adopted as the anode for lithium‐ion batteries, substantial improvement on the reversible capacity and cycling performance can be achieved for the obtained Co intercalated COF electrode (780 mAh g−1 after 200 cycles at 100 mA g−1) compared to original COF electrode (120 mAh g−1 under the same condition). The two‐dimensional COF materials with morphology justification and/or performance improvement via metal ion intercalation would promote the application of COF related electrodes for other energy‐storage fields.
2021 U.S. Virgin Islands Zika health brigade: Providing recommended pediatric health screenings for children born to mothers with laboratory evidence of possible Zika virus infection during pregnancy
Authors: de Wilde Leah H. , Harrison Cosme Jeremy , Ceesay Binta E. , Mayers Charmaine S. , Ferrol‐Hawley Janney , Canton Jacqueline , Godfred‐Cato Shana , Reynolds Megan R. , Brown‐Shuler Lessely , Randhawa Sukhdeep , Schoelles Dan , Hillman Braeanna , Carlos Maria Paz , Ambrose Tracey , Bitner Derek , Holgado Sandra , Jones Cristie , Lattin Daniel J. , Mulkey Sarah B. , Nguyen Angeline , Payne Mary , Prakalapakorn S. Grace , Shue Ann , Ellis Esther M.
Published: December 2022

Background

The United States Virgin Islands (USVI) Department of Health (DOH) conducted a second Zika health brigade (ZHB) in 2021 to provide recommended Zika‐related pediatric health screenings, including vision, hearing, neurologic, and developmental screenings, for children in the USVI. This was replicated after the success of the first ZHB in 2018, which provided recommended Zika‐related pediatric health screenings to 88 infants and children exposed to Zika virus (ZIKV) during pregnancy.

Methods

Ten specialty pediatric care providers were recruited and traveled to the USVI to conduct the screenings. USVI DOH scheduled appointments for children included in CDC's U.S. Zika Pregnancy and Infant Registry (USZPIR). During the ZHB, participants were examined by pediatric ophthalmologists, pediatric audiologists, and pediatric neurologists. We report the percentage of participants who were referred for additional follow‐up care or given follow‐up recommendations in the 2021 ZHB and compare these referrals and recommendations to those given in the 2018 ZHB.

Results

Thirty‐three children born to mothers with laboratory evidence of ZIKV infection during pregnancy completed screenings at the 2021 ZHB, of which 15 (45%) children were referred for additional follow‐up care. Ophthalmological screenings resulted in the highest number of new referrals for a specialty provider among ZHB participants, with 6 (18%) children receiving referrals for that specialty. Speech therapy was the most common therapy referral, with 10 (30%) children referred, of which 9 (90%) were among those who attended the 2018 ZHB.

Conclusions

Thirty‐three children in a jurisdiction with reduced access to healthcare specialists received recommended Zika‐related pediatric health screenings at the ZHB. New and continuing medical and developmental concerns were identified and appropriate referrals for follow‐up care and services were provided. The ZHB model was successful in creating connections to health services not previously received by the participants.
C3 – Carbon Concrete Composite – Vom größten Bauforschungsprojekt zum bedeutendsten Verband für Carbonbetonbau
Authors: Kranich Sandra , Schladitz Frank
Published: December 2022

Carbonbeton findet zunehmend Anwendung in der Praxis: im Neubau und im Bereich der Sanierung. Zahlreiche Unternehmen, Verbände und Institutionen arbeiten unter der Dachmarke von C3 – Carbon Concrete Composite daran, den Einsatz der Carbonbetontechnologie zu erleichtern, die zahlreichen Vorteile von Carbonbeton zu nutzen und somit einen wesentlichen Beitrag zur Klimaneutralität zu leisten. Dieser Aufsatz beschreibt die Anfänge der in den 1990er‐Jahren abwegig klingenden Idee und skizziert die Entwicklungsphasen von einem Bauforschungsprojekt zum bedeutendsten Verband auf dem Gebiet des Bauens mit Carbonbeton.
Repurposing antimalarial artesunate for the prophylactic treatment of depression: Evidence from preclinical research
Authors: Huang Shihao , Galaj Ewa , Wang Jinfeng , Guo Yi , Wang Shuang , Shi Mengxu , Yin Xueyong , Liu Keyao , Luo Yixiao , Meng Li , Shi Haishui
Published: December 2022

Introduction

Several studies have linked inflammation and oxidative stress with the pathogenesis of depression. Artesunate is a commonly used medication to treat malaria and has been shown to produce antioxidant, anti‐inflammatory, and immunomodulatory effects. However, its prophylactic effects on depression and depression‐related brain pathology are unknown.

Methods

In Experiment 1, using a PC12 cell line, we investigated whether artesunate can prevent hydrogen peroxide (H2O2)‐induced oxidative injury that mimics oxidative stress commonly observed in the depressed brain. Next, using lipopolysaccharide (LPS)‐induced mouse model of depression, we investigated whether artesunate can prevent behavioral deficits observed in the open field test, novelty‐suppressed feeding test, sucrose preference test, forced swimming test, and tail suspension procedure.

Results

We found that artesunate significantly prevented a H2O2‐induced reduction in PC12 cell activity, suggesting its antioxidant potential. We also found that mice pretreated with artesunate (5, 15 mg/kg) intraperitoneally (i.p.) prior to the LPS (.8 mg/kg, i.p.) treatment showed fewer and less severe depression‐ and anxiety‐like behaviors than the LPS‐treated control mice.

Conclusion

Our findings indicate that artesunate produces antioxidant effect, as well as antidepressant and anxiolytic effects. Importantly, our findings first demonstrate that artesunate can prevent LPS‐induced depression‐ and anxiety‐like symptoms, strongly suggesting its prophylactic potential in the treatment of depression and, perhaps, other psychiatric disorders associated with inflammation and oxidative stress.
Deciphering the Antimicrobial Potential of Taxus wallichiana Zucc: Identification and Characterization Using Bioassay‐Guided Fractionation
Authors: Adhikari Priyanka , Agnihotri Vasudha , Suman Sunil Kumar , Pandey Anita
Published: December 2022

Taxus wallichiana Zucc. is a high valued medicinal plant and has been mainly studied for its anti‐cancer properties. However, research on its other important biological activities, such as its antimicrobial potential, still needs attention. The focus of the present study is to investigate the antimicrobial activity of secondary metabolites of T. wallichiana needles against 3 different groups of microorganisms, i. e., bacteria, actinobacteria, and fungi. Bioactive compounds from T. wallichiana needles were separated through column chromatography, and, TLC‐bioautography. Mobile phases were optimized using Snyder's selectivity triangle. Antimicrobial spots were fractionated and compounds were identified by gas chromatography‐mass spectroscopy (GC/MS) and liquid chromatography‐mass spectrometry (LC/MS). Functional groups were characterized using Fourier transform infrared spectrometry (FTIR) and nuclear magnetic resonance (NMR) was used to identify the molecular structures. GC/MS and LC/MS data analysis confirm the presence of fatty acids (arachidic acid, behenic acid, palmitic acid, and stearic acid), vitamins (nicotinamide), and alkaloids (cinchonine, timolol), aminobenzamides (procainamide), carbocyclic sugar (myoinositol), and alkane hydrocarbon (hexadecane), having antimicrobial activity in the needles of T. wallichiana. To the best of our knowledge, this is the first report on the isolation and characterization of antimicrobial compounds from the needles of Taxus wallichiana (Himalayan yew). The data obtained from the present study will be supportive to the new drug discoveries in modern medicine with various combinations of medicinal plant's active constituents that can be used for curing many diseases.
Renal vein thrombosis after COVID‐19: A case report
Authors: Janbazi Roudsari Hamid , Negaresh Mohammad , Shirzadeh Vida , Mohammadzadeh Germi Bahman , Mirzaei Arezoo
Published: December 2022

Severe cases of coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome‐Coronavirus‐2, can lead to pneumonia or acute respiratory distress syndrome. Non‐respiratory manifestations of COVID‐19 include venous and arterial thrombosis. The disease can affect all organs and even the kidneys and lead to renal vein thrombosis where renal veins or their branches become thrombotic leading to symptoms such as flank pain, hematuria, or acute kidney damage. In this study, a case of renal vein thrombosis after COVID‐19 is introduced and the causes and complications of this disease are analyzed.
An adaptive phase‐locked loop‐less control strategy for LCL‐filtered grid‐connected inverter under complex grid conditions
Authors: Huang Min , Chen Fan , Wu Weimin , Yao Zhilei
Published: December 2022

The phase‐locked loop, as a method to extract grid voltage phase angle, is commonly used for grid‐connected inverter to synchronize the injected grid current with the grid. However, the phase‐locked loop will also bring some problems. The current loop controller, the phase‐locked loop, and the grid impedance are coupled together under the weak grid. Then, the phase angle of the inverter output impedance will be reduced, causing the system to be unstable. Moreover, the output phase angle of the phase‐locked loop participates in the coordinate transformation under the unbalanced grid voltage condition, which degrades the quality of the injected grid current generated by the inverter with high harmonic content. Therefore, a vector current control strategy without phase‐locked loop derived from direct power control is used in this paper. An adaptive linear Kalman filter algorithm is also applied to observe the voltage information and avoid the harmonic problems caused by power calculation. Finally, simulations and experiments are conducted to verify that the proposed method is effective, and the results are consistent with the theoretical analysis.
Volunteer Angling and Technology-Based Solutions Provide the First Estimate of Sea Lice Infections for Wild Coastal Cutthroat Trout Oncorhynchus clarkii clarkii
Authors: Losee James P , Dapp Derek R , Madel Gabe , Shimek Greg
Published: December 2022

Anadromous Coastal Cutthroat Trout Oncorhynchus clarkii clarkii are one of the least studied salmonids but are a highly prized target in sport fisheries in coastal waters of the Pacific Northwest. Despite an observed high prevalence of ectoparasite infections, described by sport anglers as “sea lice,” there is a paucity of data available on the spatial and temporal occurrence of infections on Coastal Cutthroat Trout. We collaborated with the angling community through social media engagement and an online application to report ectoparasites observed on sport catch. In 2018, we received voluntary reports for 1,493 Cutthroat Trout and 416 salmon catch events in marine waters from the province of British Columbia and the states of Washington, Oregon, and California. These data demonstrated that the number of argulids and copepods per trout varied according to body size, capture month, and area. To evaluate accuracy of voluntary parasite counts, we compared results to parasite counts on cutthroat from sampling events conducted by trained biologists. For both voluntary angler reports and those of biologists, spring months had a lower prevalence of argulids and copepods, argulids were common on trout, but absent on salmon, and larger trout were associated with an increased number of argulid and copepod infections.
Performance of sand filter with disc and screen filters in irrigation with rainbow trout fish effluent
Authors: Mohammad Hasani Abed , Aminpour Younes , Nikmehr Saman , Puig‐Bargués Jaume , Maroufpoor Eisa
Published: December 2022

Drip irrigation is the most suitable system for reusing effluents in agriculture, but emitter clogging is still its major drawback. Adequate filtration is needed to prevent emitter clogging, but little information is available about the performance of different filter types when using fish farm effluent. The purpose of this study was to evaluate the performance of three filtration treatments for rainbow trout effluent in drip irrigation systems: (1) sand filter (T1), (2) sand filter followed by a disc filter (T2) and (3) sand filter followed by a screen filter (T3). The treatments were tested with a constant discharge of 14.4 m3 h−1 at two working pressures of 300 and 150 kPa until reaching the backwashing threshold. For each filter, the following were computed: filtered volume per cross‐section until reaching the backwashing threshold (VB), filtered volume per cross‐section unit and head loss (V10), suspended solids removal efficiency (EF) and filter mass retention (q). T2 at 300 kPa had a significantly (p < 0.01) higher VB, whereas T1 and T3 only showed a VB of 53% and 45% at 300 kPa and 48% and 47% at 150 kPa, respectively, higher than that obtained by T2. The results suggest that using a combination of sand and disc filters at an operation pressure of 300 kPa is the best option when using rainbow trout effluent.
A 3D printed hydrogel to promote human keratinocytes' spheroid‐based growth
Authors: Rocha Tânia , Teixeira Ana Margarida , Gomes Susana G. , André António , Martins Pedro , Ferreira João , Negrão Rita
Published: December 2022

Tissue engineering uses cells and biomaterials to develop bioartificial tissue substitutes for different purposes. For example, although several skin models have been developed for pharmaceutical and cosmetic research and skin wound healing, there are few studies on 3D cultures of keratinocytes in 3D printed scaffolds. So, this work aimed to develop a 3D‐printed hydrogel scaffold to promote human keratinocyte growth. Mesh 3D scaffolds were printed using an extrusion‐based method with a 20% gelatin/5% alginate hydrogel, where HaCaT cells were cultured for 7 days. Scaffolds kept their structure for over 1 week, and their stiffness only decreased after 7 days, showing good mechanical and structural characteristics and biodegradability (27% weight lost). Viable keratinocytes (MTT assay) are aggregated into spheroids, a 3D model capable of mimicking in vivo cell properties and phenotypes. Spheroids were formed on 47% of scaffolds pores and grew over time, showing promising cell proliferation. F‐actin staining showed cells' irregular and interconnected shapes and organization over time. This method offers an easy and inexpensive solution for keratinocyte spheroid formation, which may be helpful in tissue engineering as a cell delivery system, for pharmacological or basic research, or wound healing medical applications.
Double‐conscious professional self‐expression of racial minority scientists‐in‐training
Authors: Sugiyama Keimei , jaks queen , Bilimoria Diana , Liu Han
Published: December 2022

Double‐consciousness pervades the workplace experiences of minority professionals. Prior research captures various manifestations of double‐consciousness in the workplace, yet much of what we know comes from understanding the experiences of minority professionals in predominantly White workplaces. Inherent in conceptions of double‐consciousness is the sense of twoness in one's self concept that arises from seeing oneself through the eyes of both the predominantly White profession and one's own racial community. In this study, we examine contrasts as well as commonalities in experiences of double‐consciousness across different social contexts in the socialization of minority scientists‐in‐training. We draw from qualitative data collected from 64 individuals (including 39 underrepresented minority doctoral students, and 25 faculty, staff, and administrators) in science, technology, engineering, and mathematics (STEM) doctoral programs in both predominantly White and historically Black institutions to examine and compare the factors across different contexts that influence how minority scientists‐in‐training are able to express their emerging professional identity. Our findings reveal how minority scientists‐in‐training experience twoness as both a struggle and a strength, and we develop an inductive model of how different socializations influence the double‐conscious professional self‐expressions of minority scientists in training.