bluuebunny/crossref_metadata_2025 huggingface dataset:
Sweet Syndrome "Acute Febrile Neutrophilic Dermatosis"; A Case Report at Maternity and Children Hospital, Hail
Authors: Elsdeeg Shagn , Alhejaili Maram
Published: January 2024

Background: Sweet Syndrome is a rare phenomenon with neutrophilic infiltrate into the dermis and the sudden onset of painful, larger, asymmetrical erythematous papules or nodules. This report shares management of sweet syndrome in maternity and children hospital, Hail, Saudi Arabia.
Case presentation: A 10 months old, previously healthy, boy presented with painful skin erythematous plaques or nodular eruption in the left lower calf and trunk that discharged pus and turned into ulcers. The condition was preceded by viral gastroenteritis and upper respiratory tract infection. He was clinically diagnosed with sweet syndrome, confirmed by laboratory and histopathological findings. The infant received systemic and topical steroids and was discharged from hospital in the healthy condition.
Conclusion: A thorough search for common infectious causes and a complete examination for extracutaneous manifestations are required in such cases, and after confirming the diagnosis, a step-by-step examination to rule out underlying malignancy is warranted.
Mucocele of Ventral Tongue Surface Treated with Diode Laser: Case Report
Authors: Aladhyani Ghadah , Alanazi Abdullah , Asaad Shahad , Alkahtani Abdullah
Published: January 2024

Background:
Mucoceles are harmless cystic lesions of the oral mucosa. Mucoceles are fluid-filled swellings that typically appear on the lower lip, floor of the mouth, or inner cheeks after trauma or obstruction of salivary ducts.
Case presentation:
A 10-year-old healthy female pediatrics patient, accompanied by her parents, was referred from the pediatric department to oral medicine. The patient presented with a recurrent painless swelling under her tongue for 2 months with pain when biting on it. Intraoral examination showed a pandiculated nodule on the anterior ventral surface of the tongue with overlying normal mucosa. The lesion was removed under local anesthesia (mepivacaine 2%) using a 940 nm diode laser (Epic Biolase, Irvine, CA, USA) with an initiated E4–4mm surgical tip. The patient reported minimal pain and discomfort. After one month, the patient was seen for a post-operative evaluation visit with no recurrence of the lesion and no complaints. The histological diagnosis confirmed the initial diagnosis of extravasation mucocele.
Conclusion:
The effective use of diode lasers in the current case demonstrates the efficacy of this minimally invasive therapy method. This method not only ensured that the mucocele was completely removed, but it also contributed to less postoperative pain and a speedier recovery.
Idiopathic Infantile Nystagmus; Genetics foundation and Clinical association
Authors: AlMoallem Basamat
Published: January 2024

Nystagmus is an involuntary, periodic eye movement caused by a slow drift of fixation of either jerk, pendular, or rotatory form. The clinical and molecular assessment of nystagmus can provide crucial elements for a state-of-the-art differential diagnosis. Herewith, we provide a comprehensive overview of idiopathic infantile nystagmus, one of the most common forms of infantile nystagmus that is usually reached out by exclusion of a variety of underlying causes and considered as one of the main leading causes of visual debleating disorders in early childhood.
The International Stroke Survey (ISS): A multi-country perspective of public knowledge of cerebral stroke.
Authors: AlAslani Shahd , AlShafaaei Rawan , Hamam Anas
Published: January 2024

Background:
As acute stroke remains an important leading cause of morbidity and mortality in the world, this study sought to survey the general public in four different countries, in four different continents to ascertain the level of knowledge of the public for the risk factors, and the signs and symptoms of stroke.
Methods:
This was a cross-sectional survey of the general public that was conducted via a self-administered online survey using the SurveyMonkey® platform in the United States, the United Kingdom, the Kingdom of Saudi Arabia, and Egypt. Questions on identifying the risk factors, as well as the signs and symptoms of stroke were asked. A score was given to all subjects, and they were then asked to identify the life-style changes that they thought would reduce the risk of getting a stroke.
Results:
A total of 2000 subjects were recruited via the electronic search engine at the SurveyMonkey®, 500 from each country. The data showed that subjects in Western countries agreed on dyslipidemia and lack of exercise being the top two risk factors for stroke. While the Middle Eastern subjects mostly identified smoking and having a previous stroke as the top risk factors. Regarding the signs and symptoms, Western subjects agreed perfectly that the top three were hemiparesis, heavy tongue and facial asymmetry.
Conclusion:
It was clear from the data collected in this study that the knowledge level of signs and symptoms of stroke in the general public, irrespective of the country was poor.
Trexit: A “Clean” Withdrawal from Transrectal Prostate Biopsies – Prospective Results of In-office Freehand Transperineal Biopsies Under Local Anaesthesia
Authors: Bilé Silva Andreia , Dinis Paulo Jorge , Portugal Gaspar Frederico , Rodrigues Fonseca Rita , Santos José Carlos
Published: January 2024

Introduction: Prostate biopsy (PB) may be performed by either the transrectal (TR) or transperineal (TP) approach. Cancer detection rates seem to be comparable between the two approaches. However, evidence suggests a reduced infection risk and a higher detection of tumours localised in the anterior zone of the prostate with the TP route. TP-PB is currently recommended as a first-line procedure for the diagnosis of prostate cancer (PCa) whenever available.
We sought to report the initial results of in-office freehand TP-PB under local anaesthesia in the outpatient setting.
 
Methods: We conducted a prospective study with consecutive sampling with data from men submitted to TP-PB from Sep/2019 to Sep/2021, in a tertiary care centre. A questionnaire was carried out to appraise the pain related to the procedure on a pain numerical rating scale from 0 to 10.
Presenting PSA, biopsy result and characteristics and complications that motivated a visit to the emergency department–ED – until 1 month after the PB were analysed.
Antibiotic (AB) prophylaxis was not provided to any of the patients undergoing TP-PB.
TP-PB was performed under local anaesthesia by freehand method.
 
Results: A hundred and eight (108) patients underwent TP-PB. The mean age was 66±9 years old.
The median presenting PSA was comparable in patients with positive and negative PB results (7.7 ng/mL, p=0.11).
Overall, 67/108 (62%) patients had PCa diagnosed. Clinically significant (cs) PCa (ISUP=2) was diagnosed in 42/67 (63%) patients.
The TP approach allowed the diagnosis of anterior zone PCa in 61% (41/67) of the patients (anterior zone csPCa in 63% of these), 7% (5/67) had exclusively anterior zone pathological findings. Complications leading to an ED visit were recorded in only one patient.
Patients reported only mild levels of discomfort related to the anaesthesia infiltration (3±3) and to the introduction of the US transducer (3±3). Globally, the patients ascribed a pain of 3±3 to the entire procedure.
 
Conclusion: Freehand TP-PB under local anaesthesia, without AB prophylaxis, is a well-tolerated and safe procedure, feasible as an outpatient procedure.
TP-PB provides an easy access to the anterior zone of the prostate allowing for the diagnosis of previously missed PCa.
Personzentrierte Therapie bei Borderline-Persönlichkeitsstörungen
Authors: Jessinghaus Annette
Published: January 2024

Die Arbeit zeichnet den Prozess einer Therapiestunde in der personzentrierten Behandlung einer Klientin mit einer Borderline-Persönlichkeitsstörung nach. Anhand der Fallskizze werden das störungsbezogene Vorgehen sowie das konkrete Beziehungsangebot in der therapeutischen Begegnung veranschaulicht. Die konkreten Interventionen der Autorin werden im Hinblick auf die Verwirklichung eines optimalen Beziehungsangebotes sowie den Therapieerfolg diskutiert.
Fadiga na amamentação em mães em atividade ocupacional durante a pandemia da Covid-19
Authors: Carvalho Crislaine Souza Bernardino , César Carla Patrícia Henandez Alves Ribeiro , Nicolino Rafael Romero , Granzotti Raphaela Barroso Guedes , Zuanetti Patrícia Aparecida , Campos Samara Kauany Rodrigues , Lima Lorena Maria Santana , Silva Kelly Da
Published: January 2024

Objetivo: Verificar os fatores preditores para a fadiga materna na amamentação em mães com atividades ocupacionais na pandemia da COVID-19. Métodos:  A amostra foi selecionada pela estratégia bola de neve. Composta por lactantes em atividade ocupacional que responderam questionários para obtenção de informações de dados pessoais, sociodemográficos, obstétricos e pós-natal. A fadiga foi mensurada pela Escala de Severidade da Fadiga. Resultados: Participaram 66 lactantes, com mediana de 33 anos, a maioria com alta escolaridade, renda familiar acima de três salários-mínimos, perderam a ajuda com o bebê por receio da contaminação pela COVID-19, foram submetidas à parto cesáreo, sem intercorrência no período pós-parto, não ofertaram mamadeira e sem intercorrências durante a amamentação, não tinham experiência prévia com amamentação foram orientadas, durante o pré-natal, sobre a importância da amamentação. Conclusão: Embora muitas varáveis contribuam para a intensidade da fadiga materna, neste estudo, idade materna, idade do bebê em meses, número de moradores na casa, número de filhos, número de gestações, impedimento para a amamentação após o nascimento do bebê, renda familiar, a falta de ajuda por medo do contágio, ajuda com o bebê, retorno ao trabalho, intercorrências no pós-parto, foram os fatores que mais contribuíram para o aumento da fadiga na amamentação.
Upscaling sample size for microscopical detection of nanoplastics
Authors: Hiltunen Arto , Huopalainen Joona , Häkkilä Sirkku , Damlin Pia , Hänninen Jari
Published: January 2024

The extent of nanoplastic pollution has raised severe environmental and health concerns. While the means for microplastic detection are abundant, improved tools for nanoplastic detection are called-for. State- of-the-art microscopic techniques can detect nanoplastics down to tens of nanometers, however, only from very small sample sizes (typically ∼10 µl). In this work, we describe a method that enables sampling of 1 liter of seawater by the means of correlative Raman- and SEM-techniques. This is achieved by adapting common microplastic sample purification protocols (i.e. chemical digestion) to suit the nanoplastic study. In addition, we decorate a membrane filter with SERS-property to amplify the Raman signals. Together, the purification method combined with the use of the SERS-activated-membrane-filter enables identification and imaging of individual nanoplastic particles from significantly larger sample sizes than before. In the nanoscale the average recovery rate is 5 %. These results aim to provide useful tools for researchers in the fight against plastic pollution.
Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case
Authors: Ackermann Katrin , Heubach Caspar , Schiemann Olav , Bode Bela
Published: January 2024

Recent sensitivity enhancements in pulse dipolar EPR spectroscopy (PDS) have afforded distance measurements at submicromolar spin concentrations. This development opens the path for new science, as more biomolecular systems can be investigated at their respective physiological concentrations. Here, we demonstrate that the combination of orthogonal spin labelling using copper(II) ions and trityl yields a more than 3-fold sensitivity increase compared to the established copper(II)-nitroxide labelling strategy. Application of the recently developed variable-time RIDME method yields a further approximately 2.5-fold increase compared to the commonly used constant-time RIDME. This overall increase in sensitivity of almost an order of magnitude makes distance measurements in the range of 3 nm with protein concentrations as low as 10 nM feasible, more than two times lower than previously reported. We expect that experiments at single digit nanomolar concentrations are imminent, which has the potential to transform biological PDS applications.
Bispecific PSMA-617 / RM2 Heterodimer for Theranostics Applications in Prostate Cancer
Authors: Liolios Christos , Bouziotis Danai , Lambrinidis George , Schaefer Martin , Sihver Wiebke , Salvanou Evangelia-Alexandra , Bauder-Wuest Ulrike , Benesova Martina , Kopka Klaus , Kolokouris Antonios , Bouziotis Penelope
Published: January 2024

PSMA and GRPR protein receptors are upregulated during prostate cancer (PCa) progression, and thus they have both been used for diagnostic molecular imaging and therapy of the disease. To address tumor heterogeneity, we synthesized and evaluated the bispecific PSMA/GRPR ligand (3) with a 10 atom spacer between PSMA-617 (1) and the GRPR antagonist RM2 (2) generated with click chemistry and coupled with chelator DOTA, to enable radiolabelling. Ligand 3 was radiolabelled with 68Ga, [68Ga]Ga-3 and 177Lu, [177Lu]Lu-3. [68Ga]Ga-3 was tested with PCa cell lines PC-3 and LNCaP for its affinity for GRPR and PSMA receptors, lipophilicity, for its cell-binding specificity, time kinetic binding affinities and cell-internalization. Heterodimer 3 showed specific cell binding, similar affinities for PSMA receptor and GRPR and higher lipophilicity compared to monomers PSMA-617 (1) and RM2 (2), while total internalization rates and cell-binding were superior over monomers. Docking calculations showed that the PSMA-617 (1) /RM2 (2) heterodimer 3 can have binding interactions of PSMA-617 (1) inside the PSMA receptor funnel and of RM2 (2) inside the GRPR. In vivo biodistribution studies for [68Ga]Ga-3 showed dual targeting of PSMA-positive tumors and GRPR-positive tumors and fast pharmacokinetic properties, higher cancer cell-uptake and lower kidney uptake in comparison to the monomers.
Autonomous millimeter scale high throughput battery research system (Auto-MISCHBARES)
Authors: Rahmanian Fuzhan , Fuchs Stefan , Zhang Bojing , Fichtner Maximilian , Stein Helge Sören
Published: January 2024

Discoveries of novel electrolyte-electrode combinations require comprehensive structure-property-interface correlations. Herein, we present an autonomous millimeter scale high-throughput battery research system (MISCHBARES) operated by hierarchical autonomous laboratory automation and orchestration (HELAO) which integrates modular research instrumentation and AI control. This paper will present cathode electrolyte interphase (CEI) formation in lithium-ion batteries at various potentials by correlating high-throughput electrochemistry and spectroscopy. We believe quality control and complex data analysis to be the missing puzzle piece towards more complex workflow automation. Auto-MISCHBARES integrates automatic quality control for both hardware and software to ensure high reliability through an on-the-fly fidelity assessment of each individual experiment. Data analysis is achieved through our Modular and Autonomous Data Analysis Platform (MADAP) in our presented platform, which is capable of performing a fully automated analysis of various voltammetry measurements in real-time. Integration of MISCHBARES and MADAP through HELAO enables versatile and complex active learning workflows in the discovery of new materials. We demonstrate this integrated workflow for reliable charging/discharging protocols.
COLD STRESS IN WINTER AND SPRING RICE
Authors: Ghimire Prakriti , Bhandari Mahesh K. , Regmi Nawa Raj , Panthi Bipin
Published: January 2024

In terms of area covering, production, productivity, and preference; Rice is ranked second in worldwide after wheat. Having more than 1,700 land races of rice, Nepal is considered as one of the origins for Asian rice. When there occurs out the variation in the normal temperature range in the plant, the various phenomenon like; Physiological, Cellular, metabolic and molecular disfunction is observed out which leads to death of the plant. At lower temperatures, stress tolerance can be induced by exposure to reduced temperature and is known as chilling tolerance and/or cold acclimation. Chilling tolerance is the ability of a plant to tolerate low temperatures (0–15 ◦C) without injury or damage, while cold acclimation is an enhanced tolerance to the physical and physiochemical vagaries of freezing stress. It limits the geographic distribution of plants and reduces the yield of some crops by shortening their growing season. Rice is mainly considered as a chill sensitive crop. The general aims of the review paper are to identify the various cold stress symptoms seen in rice and also recommend the best solution for removing cold stress on rice i.e., on both farmer level and researcher level. Therefore, this review focuses on the increasing in tolerance level of the cold stress.
TISSUE CULTURE AND ITS APPLICATION IN MODERN AGRICULTURE
Authors: Mahato Asmita , Chaudhari Goma , Banjade Gaurave , Uprety Shreesha
Published: January 2024

Tissue culture is a technique of growing plant cells, tissues and organs in an artificial prepared medium under aseptic conditions, which was invented by Gottlieb Haberlandt in 1902. Plant tissue culture is based on cellular totipotency, dedifferentiation, and redifferentiation. This paper overviews about procedures and applications of tissue culture by the analysis of numerous published studies. Compared to normal plant breeding methods, which take substantially longer, crops produced through tissue culture is developed through accurate and time-saving methods. It enables the recovery of embryos created by incompatible crosses, eliminates the phenomena of seed dormancy seen in plant species, and the life cycle of some species whose life cycles are relatively long are shorten. Even in situations where the species would typically have poor rates of multiplication, tissue culture enables the quick generation of a large number of plants. Also tissue culture required less space for multiplication of clones. An agriculturally valuable phenotype should come from the genetic diversity recovered from tissue culture regenerated plants. There are numerous issues arises in tissue culture. Researchers are having difficulty propagating plant tissues and acclimating in vitro produced plants in their natural habitat. However, greater understanding and study will lead to more widespread use of tissue culture.
UTILIZATION OF HETEROSIS IN CROP IMPROVEMENT
Authors: Chaudhari Goma , Mahato Asmita , Banjade Gaurave , Uprety Shreesha
Published: January 2024

Heterosis is a natural phenomenon in which offspring of distinct species or offspring of species hybrids exhibit better biomass, faster rates of growth, and higher fertility than either of their parents. In comparison to either parents or their self-pollinated cousins, the offspring of two homozygous inbred lines are more robust and have bigger heights and weights. With naturally cross-pollinating species the degree of heterosis is frequently higher than in self-pollinating crop. One of the most significant advancements in agriculture was the development of hybrids. Today, heterosis is widely used without having a thorough understanding of the underlying molecular and genetic concepts. By enabling the best possible exploitation of crop yield and stability, the understanding of the genetic and epigenetic framework underlying heterosis would be a major discovery that would revolutionize current plant breeding
MODIFIED COMPUTATIONAL METHOD BASED ON INTEGRAL TRANSFORM FOR SOLVING FRACTIONAL ZAKHAROV-KUZNETSOV EQUATIONS
Authors: Hamadamen Mudhafar Hamed , Abdulazeez Sadeq Taha , Sadiq Murad Muhammad Amin
Published: January 2024

This work proposes a new computational method, namely the He-Elzaki transform method (HETM) formulated by He’s variation iteration method and modified Laplace transform called Elzaki integral transform to solve nonlinear fractional Zakharov-Kuznetsov equations. The fractional derivatives are described by Caputo sense. The beauty of this technique is that one has no need to evaluate the Lagrange multiplier by integration or taking the convolution theorem. The suggested method is implemented on two examples and the results obtained are compared with those of the Variation iteration method (VIM), homotopy perturbation transform method (HPTM), and new iteration Sumudu transform method (NISTM), and optimum homotopy analysis method (OHAM). The innovative computational technique is an efficient high accurate method and facilitates solving fractional differential equations.
BESSEL MATRIX POLYNOMIALS AND FIFTH-ORDER DIFFERENTIAL EQUATIONS
Authors: El-Baghdady Galal I. , El-Gamel Mohamed , Abd El-Hady Mahmoud
Published: January 2024

There are numerous methods for numerically solving a fifth-order ordinary differential equation. We show in this paper that the Bessel matrix polynomials method is a powerful tool for numerically solving this equation. Our method is tested on examples, and it is compared to other methods. It is demonstrated that the Bessel matrix polynomials method produces good results.
APPLICATION OF DYNAMIC REGRESSION (DR) TO MODELING OF THE GROSS DOMESTIC PRODUCT (GDP) OF NIGERIA
Authors: B. Biremo , I. Raji , S.O. Ilugbo
Published: January 2024

This study examine the significant contribution of Nigeria Stock Market towards the Gross Domestic Product. The main objective of this work is to assess the level of Stock Market stability in Nigeria by applying Dynamic Regression to modeling of Gross Domestic Product (GDP) using the Quarterly Gross Domestic Product at 1990 constant basic prices of Nigeria from the first quarter of 1985 to the third quarter of 2013. Quarterly all Share Index of the Nigerian Stock Exchange from the first quarter of 1985 to the fourth quarter of 2013 and finally Quarterly Market Capitalization of the Nigerian Stock Exchange for the same period. It was observed that the relationship is statistically significant, which allows the stock market to have an impact on the Nigerian Economy. It was concluded that Government and Economic planner should take more advantage of statistical tools in studying the relationship between the GDP movement and the Stock Exchange.
A COMPARATIVE STUDY OF TWO METHODS FOR SOLVING QUADRATIC EQUATIONS
Authors: Boadu Samuel Kwaku , Bannor Gyasi Alfred
Published: January 2024

For the past millennia, various methods had been developed to solve quadratic equations with one unknown. Among high school mathematics curriculum worldwide, quadratic equations teaching and learning intensively utilizes the completing squares method. The present study compared Loh’s method to completing squares to examine the difference in students performance in solving quadratic equations. A random sample of 21 students were put into control (n=11) and experimental groups (n=10). The experimental group solved two essay type questions using Loh’s method whiles the control group used completed squares. Students test scores were analysed non-parametrically by Mann-Whitney U test. The results revealed statistically significant difference in test scores between control group (median=2.00,n=11) and experimental group (median=5.00,n=10). The median for the experimental group was significantly higher than that of the control group. The study recommended that teachers, curriculum developers and policy makers should be highly interested in intuitive approaches, particularly Loh’s method, that discourage rote memorization.
A UNIQUE METHOD FOR THE TRISECTION OF AN ARBITRARY ANGLE
Authors: Roy Probir
Published: January 2024

Trisection of an arbitrary angle is considered an impossible event in mathematical history. In this paper, we are trying to establish a general procedure for trisecting an arbitrary angle using only an unmarked straightedge and a compass. The basic geometrical compass constructions described in our main results section will ensure the possibilities of known and unknown angles trisection indeed. Before reaching the main results or general trisecting procedure, we will try to prove that Angles of sixty, thirty, seventy-five, forty-five, and ninety degrees can be trisected successfully by following the way of Archimedes and other discrete endeavors. Although based on algebra, Pierre Laurent Wantzel declared the verdict, “Arbitrary angle trisection is impossible.” we experienced that our achieved procedure was possibly not arrested by this verdict. After applying our general process to trisect an arbitrary angle, we hope readers can trust algebra cannot affect the successful geometrical constructions of angle trisection.
INVESTIGATING HINDRANCE FACTORS WHICH FORESTALLED TEACHERS’ PARTICIPATION IN PERFORMANCE CONTRACTS IN SENIOR HIGH SCHOOLS IN GHANA
Authors: Boadu Samuel Kwaku , Bannor Gyasi Alfred
Published: January 2024

An online survey was conducted on a sample of 32 senior high school mathematics teachers in Kumasi senior high technical school using virtual snowballing technique. The study investigated the hindrance factors to teachers’ participation in performance contracting in senior high schools in Ghana. The study sought to conduct principal component analysis (PCA) on teacher contracting construct to identify the most important factors which had forestalled the implementation of teacher contracts in senior high schools in Ghana. Data was collected using researcher designed questionnaires of close-ended types on an evaluative continuum ranging from strongly disagree (SD) to strongly agree (SA) with alpha-reliability of 0.72. Data was analysed using both descriptive and multivariate inferential statistical techniques, particularly Exploratory Factor Analysis. Three (3) important factors (Teachers’ Perception, Information on PCs and Relevance of PCs) were extracted by principal component analysis of teachers’ responses. The results revealed that there should be strategies to develop positive perception of performance contracting in teachers through the provision of appropriate information on the relevance of teachers’ participation in performance contracting in senior high schools in Ghana.
A COMPREHENSIVE APPROACH TO EVALUATING SOLUTIONS OF DIFFERENTIAL EQUATIONS WITH BOUNDARY CONDITIONS USING LAPLACE TRANSFORM
Authors: Bello G. , Akpootu D. O.
Published: January 2024

This paper employed the use of Laplace transform to obtain solutions of differential equations of the first and second order with given boundary conditions, also the study investigated the pattern of variation exhibited graphically by the various solutions of differential equations at x = 0 to 12. The results in this study revealed that the solutions obtained usually contain exponential functions, while the differential equations with sine and cosine functions has solution that contains exponential and sine function. Furthermore, the differential equations with cosine function has solution that contain sine function only while differential equations that contain a perfect square multiple of f(x) in which the differential equation is equated to zero may have a solution that contain a sine function only. The graphically representation shows different pattern of variation depending on the solutions of the evaluated differential equations.
Comparative Analysis of Laparoscopy Versus Laparotomy Approaches in Treating Ectopic Pregnancy
Authors: Miao Hui
Published: January 2024

Objective: To compare and analyze the effects of laparotomy (AS) and laparoscopic surgery (LS) on ectopic pregnancy (EP). Methods: The surgical trial initiated case extraction in January 2017 and concluded in May 2023. The subjects comprised 30 cases of EP, categorized into two groups of 15 cases each based on the selected surgical method during treatment for subsequent analysis and comparison. EP patients in Group A chose AS surgical treatment, while those in Group B opted for LS surgical treatment. The perioperative parameters, complication ratio, survival status score (SF-36), and postoperative curative effect values were compared between the two groups of EP patients. Results: Throughout the perioperative period, various parameters such as blood loss level, operation time, abdominal pain relief time, ambulation time, catheterization time, exhaust time, and hospitalization time were recorded and compared between the two groups of EP patients. Complication ratios were documented and compared in EP patients from both groups post-operation. The test results indicated a lower value for complications in Group B (P < 0.05). SF-36 scores of EP patients in both groups were assessed and compared post-operation, with the test result indicating a higher value for Group B (P < 0.05). The postoperative curative effects of EP patients in both groups were evaluated and compared, revealing overall similarity between the two groups (P > 0.05). Conclusions: The curative effects of AS and LS surgery in EP are similar, but LS surgery demonstrates better prevention and control of complications, reduced bleeding and trauma, and faster postoperative body recovery. Consequently, the prognosis and survival status are superior in LS surgery, providing valuable reference points.
Effect of Individual Midwifery Nursing Intervention on Delivery Outcomes of Older Women
Authors: Xu Guanghua , Chen Shijia
Published: January 2024

Objective: To investigate the impact of individualized midwifery care on delivery outcomes among older women. Methods: A total of 72 cases involving elderly puerpera, admitted to the hospital from June 2022 to June 2023, were randomly assigned to two groups. Group A received individual midwifery intervention, while Group B received routine obstetric intervention. The mode of delivery, maternal emotional score, and maternal vital signs were compared. Indices such as total labor duration, postpartum hemorrhage, and nursing satisfaction were also assessed. Results: The cesarean section rate in Group A was significantly lower than that in Group B (P < 0.05). Following nursing, the SAS and SDS scores in Group A were lower than those in Group B, and indicators such as SBP, DBP, and HR were also lower in Group A (P < 0.05). The total labor duration was shorter in Group A, and the amount of postpartum bleeding at 24 hours was lesser compared to Group B (P < 0.05). Furthermore, parturients in Group A expressed higher satisfaction than those in Group B (P < 0.05). Conclusions: Individualized midwifery care for older women proves effective in reducing the cesarean section rate, shortening the labor process, and minimizing bleeding. These findings underscore the practicality and feasibility of implementing individualized midwifery care for this demographic.
Исследование электронной структуры и моделирование молекулярных перегруппировок MOCVD прекурсоров для прогнозирования их термической стабильности при испарении на примере гетеролептических комплексов меди(II)
Authors: Крючкова Н.А. , Стадниченко А.И. , Коротаев Е.В. , Крисюк В.В.
Published: January 2024

На примере изоструктурных гетеролептических комплексов меди [Cu(acаc)(hfac)]2 (1) и [Cu(ki)(hfac)]2 (2) рассмотрен подход к прогнозированию устойчивости при испарении металлорганических прекурсоров для химического осаждения из газовой фазы. С помощью расчетов с использованием теории функционала плотности (density functional theory, DFT) и данных рентгеновской фотоэлектронной спектроскопии (X-ray photoelectron spectroscopy, XPS) было изучено распределение электронной плотности в биядерных молекулах (1) и (2). Обнаружено, что комплексы имеют одинаковый состав и строение верхней занятой молекулярной орбитали ВЗМО (highest occupied molecular orbital, HOMO) и нижней свободной молекулярной орбитали НСМО (lowest unoccupied molecular orbital, LUMO), близкие значения энергии связей металл-лиганд и мостиковых связей Cu-O в димерах, одинаковые заряды на донорных и центральных атомах. Показано, что различие в устойчивости исследованных гетеролептических комплексов к диспропорционированию при нагревании в конденсированной фазе с образованием гомолептических комплексов объясняется кинетикой процесса. Предложен механизм реакции термически активированного обмена лигандами, заключающийся в серии перегруппировок димерных комплексов в кристаллах. На основании рассчитанных значений ΔE и ΔG для каждой стадии процесса показано, что для 2 существует энергетический барьер, обеспечивающий его более высокую термическую устойчивость по сравнению с 1.
Relationship between postprandial hyperglycaemia and Progression of Diabetic Nephropathy
Authors: S.Abdul-Razzaq Al-hilli Ali , K. Abdul-Kareem Hazem
Published: January 2024

Measurement of glycosylated hemoglobin (HbA1C) remains the gold standard for the assessment of glycemic control in patients with type 2 diabetes. Recent investigations have studied the correlation between HbA1C levels and other aspects of glucose metabolism, specifically, postprandial glucose (PPG). The results suggest that PPG is also important to overall glycemic control and may be a better index of glucose regulation than no effect on FPG. Thus, all aspects of glucose metabolism appear to be clinically relevant and should be monitored for effective diabetes management. This study defines the clinical significance of postprandial hyperglycaemia regarding the development of diabetic nephropathy.
THE USE OF ALPHA BLOCKERS IN TREATMENTOF LOWER URETERIC STONE
Authors: Alkinany Ali Hamdan
Published: January 2024

Depending on the fact that alpha adrenergic receptors are present in the ureter, the alpha blocker (terazosin) has been added to the conventional treatment of ureteric colic due to lower ureteric stone in hundred patients, to asses its advantage in hasting the passage of lower ureteric stone. The patients were selected on the bases of having a stone of one cm or less in the lower ureter discovered by sonography. The patients followed after ten days by sonography if the stone not pass before that.Eight patients developed intolerable side effects (dizziness and postural hypotension) so that terazosin was stopped and twenty patients not come back for follow up. Those patients were excluded from the study. Sixty-six patients, from the remaining 72 patients, (91.6%) pass the stone within ten days. Fifteen (22.7%) of them pass the stone after three days, nineteen (28.8%) of them did so after five days and eighteen (27.3%) patients after one week, in fourteen(21.2%) patients the stone disappear in the sonography taken after ten days. Six patients (8.3%) need urological interventions as the stone failed to pass even after two course of therapy. In conclusion, the use of alpha blocker (terazosin) seemed beneficial in hasting the passage of lower ureteral stone.
Curing of plasmid contents of Proteus spp. isolated from urinary tract infections in AL- Diwaniyah city
Authors: H. AL-.Hamadan Adnan , N. Hussein Azhar , A. AL-Nashaa Ali
Published: January 2024

This study included isolation and identification of Proteus spp . from urinary tract infections of Gynecology and padiatrics Hospital teaching in Diwaniyah cityand investigated the virulence factors connected with pathogenicity of this bacteria. It aims also at curing of plasmid contact by means of using some chemical materials. The bacteria Proteus spp. Isolates formed 16% which belong P. mirabilis and P. vulgaris from bacterial causes of urinary tract infection in children. The isolates of this bacteria has some physiological characteristics which represent virulence factors related to the ability of bacteria to make infection . It seems that 80% from these isolates were capable to Haemagglutination of RBCs . These isolates produce also Haemolysine enzyme. It was found that percentage of production was 60% . As for Blactamase enzyme production 40% of these bacteria isolates showed ability to produce his enzyme. Moreover, only 20% from Proteus isolates showed ability to produce bacteriocin production. All these isolates were not able to produce capsule production. When testing the resistance of Proteus isolates toward 8 different commonly used antibiotics in treatment of urinary tract infection, results showed that the isolates have different resistance depending on the type of antibiotic and the strain of the isolates. All these isolates were completely resistance Nitrofurantion in 100% while the least resistance toward Nalidixic acid and Gentamicin reached 20% for both. The results showed that there were DNA plasmid in 3 bacteria isolates but there was no relationship between the plasmid bands and resistance toward antibiotics. The P. mirabilis isolate which contained 4 plasmid bands was treated with SDS and Ethidiun bromide in an attempt to curing plasmid bands. The result showed that this isolate lost the ability to produce the majority of virulence factors that caused this disease and lost its resistance for som antibiotics especially Nalidix acid , Ampicillin and Choramphenicol. The ethidium bromide was the most effective in curing process since the resultant strain aest all plasmid bands.
Microbial Flora in Stable Chronic Plaque Psoriasis ( A random study of 12 patients )
Authors: Abdel Jaleel Usama , Natheer Lateef Qabas , Emad Daem Nassam
Published: January 2024

Psoriasis vulgaris is a common, chronic, recurrent, inflammatory disease of the skin characterized by round, erythematous, dry scaly plaques of various sizes. The lesions have predilection for he scalp, nails and extensor surfaces of limbs, elbows &knees. Psoriasis is characterized by three main pathogenic features: abnormal differentiation, keratinocyte hyperproliferation & inflammation .Accelerated epidermopoisis has been considered to the fundamental pathologic event in psoriasis (1). The cause for that is still unknown, however, psoriasis is thought be to an auto-immune disorder influenced by some inheritance interplaying with acquired environmental factors (i.e. stress, hypocalcaemia, hormonal disturbances, infections).Due to the strong association between microbial skin flora &infections influencing psoriasis, we should focus on this flora & its change.
The modifiable risk factors of hypertension in youths
Authors: Dh. Mehdi Al-Zubaidi Riyadh
Published: January 2024

Objective: To verify the modifiable cause(s) of hypertension in youths.Method: It is a prospective observational study, it was done in out patient private clinic in Kerbala city during the period between May 2004 and October 2006 .three hundred and fifty persons were included, the ages of all persons ranged between 20 and 35years, but 236 were hypertensive and 114 were normotensive.The main parameters that were studied included; body mass index (BMI) ,total serum cholesterol and smoking.

Results: All the hypertensive patients belong to families with history of hypertension, 80.5% of them were hypercholestremic,64.4% were obese and 53.8% were smoker. On the other side, only 21% of the persons of the normotensive group belonged to families with hypertension , none of them were obese, but 7.9% were hypercholestremic and 13.1% were smoker.Conclusion: hypercholestremia,obesity and smoking are a modifiable causes of hypertension in youth. Early recognition, education and treatment of hypercholestremia plus weight reduction and cessation of smoking may prevent or reduce the severity of hypertension and hence its hazardous complication later on.
Delayed Arrival of Stroke patients to the Hospital
Authors: K. Al- Ubaidy Kfah
Published: January 2024

Background: Although recent advances have been made in the treatment of acute stroke, patients often arrive at the hospital too late to receive the maximum benefit from these new therapies. Objective: To investigate factors that influence the time from symptom onset to hospital arrival (delay time) for patients with stroke. .Methods: Prospective observational study by recording the patient's characteristics, final diagnosis, and admission delay for all suspected acute stroke admitted patients within 3 days of onset.Results: 246 stroke patients were studied at Al-Dewania teaching hospital, the median age of the patients was 63 years, 125 were male. The median delay time was 11.6 hours, 6.1% of patients arrived within 3 hours, 18.3% were arrived within 6 hours., Middle age ,male , first stroke ,mild neurological deficit, living in rural areas ,abscess of ambulance transport and low medical public knowledge of stroke significantly delay time of presentation to the hospital.Conclusion: Increase public awareness of stroke symptoms and the need to seek early medical attention with direct transport to the hospital better by ambulance will be required for effective treatment of acute stroke.
The frequency of ophthalmia neonatorum in hospitalized neonates and newborn babies delivered in the maternity and children teaching hospital in Diwaniah
Authors: Mojar Al-Shamsi Mohammed , Hamad Al-Hamdani Adnan , Abdullah Dawood Najlaa
Published: January 2024

Objectives:Determine the frequency of ophthalmia neonatorum among hospitalized neonates and those delivered in the labor room and operation theatres in the maternity and children teaching hospitals in Diwaniah in addition to determination of the causative microorganisms and their antibiotic sensitivity.Materials & methods:Two hundreds seventy conjunctival swabs were collected randomly from neonates admitted to the septic and aseptic neonatal care units and newborn babies delivered in the labor room and operation theatres in the maternity and children teaching hospitalDiwaniah during the period from September 2002 to February 2003.Results : The clinical and microbiological diagnosis of ophthalmia neonatorum was made in 190 neonates ( 70.3 % ) , 154 cases were due to Gram positive bacteria ( 84.6 % ) and 28 were due to Gram negative bacteria ( 15.4 % ) , six cases were due to Candida . Mostinfections were in neonates aged 1- 5 days . Gram positive bacteria were sensitive to Cefotaxime and resistant to Amikacin , while Gram negative bacteria were sensitive to Tetracycline.Discussion : The results were presented and compared with other studies and concentration on epidemiological and microbiological issues was made. This article is derived from M Sc Thesis submitted by mrs Najlaa Abdullah in partial requirements for the degree of M Sc inMicrobiology 2004
The Effect of Methyl dopa on serum lipid profile in rat.
Authors: Mohammed Abbass AL-Hussueni Laith
Published: January 2024

Evidence liking hypertension and dyslipidemia are very important in deciding which antihypertensive drug is going to be describe to hypertensive patient who had or at risk to had dyslipidemia. Antihypertensive drugs which have neutral effect or preferably beneficial effect on lipid profile are the first choice in those patients. Drugs with harmful effect on serum lipid profile may add another problem to the patient and increase the risk of complications. 

Purpose:This study is carried on to evaluate the effect of methyl dopa on serum lipid profile.Methods:Twenty rats enrolled in the experiment given atherogenic diet for twelve weeks then randomly divided into two groups, first group received 33 mg /Kg /day P. O Methyl dopa dissolved in 2 ml distilled water given by nasogastric tube twice daily and serve as central group. The treatment continues with atherogenic diet for another twelve weeks. The serum lipid profile namely triglyceride, total cholesterol, LDL-cholesterol (low density lipoprotein cholesterol) HDL-cholesterol (high density lipoprotein cholesterol) and HDL-cholesterol / total cholesterol ratio were estimated before and after the treatment. The statistical analysis was done using ANOVA with level of significance P<0.05.Result:Methyl dopa was found to have no effect on serum triglyceride level and on total cholesterol serum level but it causes significant decrease in LDL-cholesterol serum level and significant increase in HDL- cholesterol serum level in comparison to control group.Conclusion:Methyl dopa has beneficial effect on serum lipid profile as it causes decrease in LDL-cholesterol level which is the atherogenic portion of cholesterol and causes increase in HDL-cholesterol level which is the protective portion of cholesterol. This effect justify it's use in patients who have or at risk to have dyslipidemia.
Study Of The Congenital Malformations Causing Dystocia In The Najif Obstetric Hospital
Authors: Salaal Mohammad Abdul Hadi , Yousif Abid Hady , Abid Jwad Wedad
Published: January 2024

The present study was conducted in the obstetric hospital in the number of infected neonatal by congenital malformations in the period extend among October , November and December in the year of 1999 . The present study revealed the congenital malformation percentage was 1% , 1.46% and 1.82% for the three months respectively and including congenital malformation of the cardiovascular system , digestive system , nervous system , muscular system and down s syndrome as well as Edward s syndrome.The congenital malformations was due to acquired or environmental factors , or exposure of the pregnant women to large doses of radiation or certain medical drugs or the pregnant women were suffering from malnutrition also psychiatry emotional as well as the shocks during the pregnancy period .
The Symptom Profile of Generalized Anxiety Disorder in Iraqi Patients
Authors: A. Monicher Al- Zaidy Adel
Published: January 2024

Generalized Anxiety Disorder (GAD) is a common psychiatric disorder, which may cause significant distress and disability. This study was an attempt to identify the symptom frequency of this significant disorder among the patients attending the only out patient clinic in Al-Diwanyia Teaching Hospital (180 Km south of Baghdad). Headache (75%), Fatigue (70%), Palpitation (67.5%), Chest pain (66.6%) and Persistent irritability (64.1%) were the most frequent symptoms in 120 outpatients with a diagnosis of GAD.
Evaluation of Hepatitis B Virus Vaccination among Children in Al-Diawynia City
Authors: N. Al-Thwani Amina , A.M. Al-Rashedi Nihad , R. Omer Ali
Published: January 2024

This study attempts to determine the protective level of antibodies against hepatitis B surface antigen among vaccinated and unvaccinated children in Al-Diawynia city, age ranging 1- 10 year. A total of 220 blood samples have been collected and tested for detection of serological markers of hepatitis B virus (HBsAg, anti-HBs and anti- HBc). They included 150 children represented the vaccinated group and 70 children represented the unvaccinated group. Prevalence of anti-HBs was higher in vaccinated children 67.3% than in unvaccinated children 3.3%. Anti-HBc was not found in vaccinated children, while 4.2% in unvaccinated children. The distribution of protective level is divided to less than 10; 10 100; and 100-more than 500 mIU/ml among studies groups that have anti-HBs 14(9.3%); 34(22.6%); and 53(53.3%) of vaccinated and (0.0%); (1.4%); and 2(2.8%) of unvaccinated group. Finally, prevalence of protective antiHBs level according to the doses received by vaccinated group has revealed that 66% of those who received the three primary doses.
Ocular manifestations of Rheumatoid arthritis
Authors: Majied Hamied Furkaan
Published: January 2024

Rheumatoid arthritis is the most common inflammatory arthritis of rheumatoid diseases which are group of immune mediated multisystem diseases.To find out the clinical ocular manifestations of rheumatoid arthritis & to ensure the importance of ophthalmologic assessment for each patient with rheumatoid arithritis.56 patients attendant to the rheumatological unite in Al-Diwaniya Teaching hospital, examined by (Visual acuity, slit lamp biomicroscopy, tonometry, tear breakup time, Schirmer test, & fundoscopy).of 56 patients; 18(32%) had positive ocular findings. The most common finding was dry eye; 9(18%) of patients.