bluuebunny/crossref_metadata_2025 huggingface dataset:
An assessment of SLAP type 5 lesions using proton density oblique sagittal imaging in magnetic resonance arthrography
Authors: Ongen Gokhan , Gokalp Gokhan , Nas Omer Fatih
Published: December 2021

Background

Bankart lesions accompany superior labrum anteroposterior (SLAP) lesions; these are called SLAP type 5.

Purpose

To compare SLAP type 5 lesions using routine magnetic resonance arthrography (MRA) and thin-slice oblique sagittal proton density (PDW) sequences and correlation operation results.

Material and Methods

In total, 181 patients were admitted with shoulder instability. The study was completed with 44 patients. The presence or absence of isolated Bankart and SLAP type 5 lesions in routine MRA and PDW oblique sagittal images were evaluated separately. Absence of rupture scored 0 points, suspected ruptures scored 1 point, and apparent ruptures scored 2 points. The two scores were compared with the shoulder arthroscopy findings.

Results

According to the findings in the shoulder arthroscopy, 40 patients had Bankart lesions and 17 patients had accompanying SLAP type 5 lesions. To detect a Bankart lesion, there was no significant difference between routine MRA sequences and PDW oblique sagittal images ( P = 0.061). Routine MRA sensitivity was 95%, specificity 25%, positive predictive value (PPV) 92%, negative predictive value (NPV) 33%, while for PDW oblique sagittal images, sensitivity was 75%, specificity 100%, PPV 100%, and NPV 28.5%. In 8/17 type 5 SLAP lesions, routine MRA detected sensitivity 47%, specificity 92.6%, PPV 80%, and NPV 73.5%; in 14/17 SLAP type 5 lesions, PDW oblique sagittal images detected sensitivity 82%, specificity 100%, PPV 100%, and NPV 90% ( P = 0.015).

Conclusion

The PDW oblique sagittal images may play a significant role in assessing the anterior and superior extent of the tears.
Wealth of children from single-parent families: Low levels and high inequality in Germany
Authors: Lersch Philipp M , Grabka Markus M , Rüß Kilian , Schröder Carsten
Published: December 2021

Families’ economic wealth is a resource that can provide children with crucial advantages early in their lives. Prior research identified substantial variation of wealth levels between different family types with children from single-parent families being most disadvantaged. The causes of this disadvantage, how much the disadvantage varies between children and how the non-resident parents’ wealth may potentially reduce the disadvantage remain unclear. To address these research gaps, we use data from the German Socio-Economic Panel (2002–17) to examine the level of and inequality in wealth for children from single-parent families using recentred influence function regression and decomposition analysis. We replicate earlier findings of a large wealth disadvantage for children in single-parent families. We find that the wealth disadvantage can be mainly explained with compositional differences in household income and employment characteristics. Beyond level differences, inequality between children from single-parent families is higher than for other family types and this inequality can only partly be explained by observed demographic and socio-economic characteristics. When considering the wealth of non-resident parents, the wealth disadvantage of children in single-parent families is reduced but remains substantial.

JEL-codes: D31, D1, J1
Encoding polysemy in the news
Authors: Boxman-Shabtai Lillian
Published: December 2021

Although media-audience encounters are always potentially open to different interpretations, little is known about the textual mechanisms that encourage polysemy. Focusing on a story about a CEO who pledged to drastically cut his pay to increase his employees’ salaries, this study compared news reports that covered the same event but were met by different levels of polysemy in their reception. Through a combination of frame and semiotic analysis, the study pinpoints differences in content and style between news stories that were met by interpretive convergence from audiences (low polysemy) and those that were met by interpretive divergence (high polysemy). Based on these differences, a typology of three textual mechanisms is offered to explain the range of polysemy in the news: the attributes and representation of characters, the use of empiricism versus mythology in structuring conflict, and the level of closure versus uncertainty in the story’s conclusion.
Walking distance in incremental shuttle walking test as a predictor of physical activity in patients diagnosed with low-risk chronic obstructive pulmonary disease
Authors: Egoshi Shojiro , Horie Jun , Nakagawa Akinori , Matsunaga Yuriko , Hayashi Shinichiro
Published: December 2021

Objectives:

Research on the determinants of physical activity in mildly symptomatic patients with chronic obstructive pulmonary disease is lacking. This study examined the predictors of physical activity in patients with low-risk chronic obstructive pulmonary disease.

Methods:

A total of 41 male patients with chronic obstructive pulmonary disease belonging to Group A of the Global Initiative for Chronic Obstructive Lung Disease were included. Regarding the objective index, the physical activity (number of steps/day and the amount of Ex (metabolic equivalent × hours)/day) of the participants was measured with a tri-axis accelerometer. In addition, regarding the evaluation index, respiratory function and dynamic lung hyperinflation were measured by a spirometer, skeletal muscle mass was measured using bioelectrical impedance analysis, skeletal muscle strength (grip and lower limb muscle strength) was measured using a dynamometer, exercise capacity was measured by the incremental shuttle walking test, and health-related quality of life was measured.

Results:

Significant correlations were found between the number of steps per day and age (ρ = −0.501, p < 0.01), forced vital capacity predictive values (ρ = 0.381, p < 0.05), dynamic lung hyperinflation (ρ = 0.454, p < 0.01), grip strength (ρ = 0.318, p < 0.05), and walking distance in incremental shuttle walking test (ρ = 0.779, p < 0.01), but not skeletal muscle mass, lower limb muscle strength, or health-related quality of life. A multiple-regression analysis with the number of steps per day as the dependent variable extracted only walking distance in incremental shuttle walking test, yielding a moderate single-regression equation (steps/day = −934.909 + 11.052 × walking distance in incremental shuttle walking test, adjusted R2 = 0.548, p < 0.001).

Conclusion:

It was suggested that the amount of physical activity of patients with low-risk chronic obstructive pulmonary disease could be predicted by walking distance in incremental shuttle walking test.
Acute Respiratory Distress Syndrome in a Carrier of an Interleukin-36 Receptor Antagonist Mutation With Generalized Pustular Psoriasis
Authors: Baniel Avital , Bar-Ilan Efrat , Hilerowicz Yuval , Merdler Ilan , Shkury Eden , Sarig Ofer , Eskin-Schwartz Marina , Sprecher Eli
Published: December 2021

Background

Generalized pustular psoriasis of von Zumbusch is a rare variant of psoriasis often accompanied by systemic, sometimes life-threatening, symptoms. Generalized pustular psoriasis sometimes arises in pregnancy.

Case report

A 31-year-old female, with a history of schizophrenia and recurrent episodes of gestation-associated pustular psoriasis, was admitted to our department because of a generalized pustular rash during the 22nd week of her fifth pregnancy. Clinical and histopathological examinations were suggestive of generalized pustular psoriasis (von Zumbusch type). During this hospitalization, she developed acute dyspnea, fever, tachycardia, and marked leukocytosis. An extensive workup failed to reveal an infectious, cardiac, or pulmonary abnormality, while severe respiratory distress necessitated mechanical ventilation. Radio-imaging revealed diffuse alveolar infiltrates consistent with acute respiratory distress syndrome (ARDS). In the absence of any other plausible cause, ARDS was considered as secondary to her skin disease. Genetic base was suspected, and genetic analysis uncovered a novel mutation in IL36RN encoding the IL-36 receptor antagonist. Only 15 cases of ARDS secondary to psoriasis have been described to date. This is the first report of this very rare complication in a known carrier of an IL36RN mutation. The fact that IL36RN is abundantly expressed in the lung as well as in the epidermis may underlie the unusual clinical features of this dramatic case.

Conclusion

The present case suggests the need to carefully monitor patients with pregnancy-associated generalized pustular psoriasis for possible life-threatening pulmonary complications and the possible link to IL36RN mutation.
Acute lymphoblastic leukemia in older adults: curtain call for conventional chemotherapy?
Authors: Luskin Marlise R.
Published: December 2021

Unlike younger adults with acute lymphoblastic leukemia (ALL), older adults are rarely cured due to a combination of intrinsic disease resistance and treatment-related toxicities. Novel therapeutics such as inotuzumab ozogamicin, blinatumomab, venetoclax, and ABL kinase inhibitors have high activity in ALL and are well tolerated by older adults. Frontline treatment regimens for older adults using novel therapeutics with reduction or omission of conventional chemotherapy are being developed with early results demonstrating high remission rates and lower toxicity, but long-term efficacy and toxicity data are lacking. Collaboration between academic and pharmaceutical stakeholders is needed to develop clinical trials to define the optimal treatment regimens for older adults with ALL.
Whom should we treat with novel agents? Specific indications for specific and challenging populations
Authors: Wilde Lindsay , Kasner Margaret
Published: December 2021

A relative wealth of new therapies for acute myeloid leukemia (AML) have led to a rapid shift in treatment paradigms for this disease. Understanding whom, when, and how to treat is more complex than ever before. Here we explore whom to treat with these available new therapies, focusing on special patient populations that include older adults, those with relapsed disease, and those with TP53-mutated AML. These high-risk subgroups are some of the most challenging to care for, but novel treatments are providing them with new hope.
What else do I need to worry about when treating graft-versus-host disease?
Authors: El-Jawahri Areej
Published: December 2021

Graft-versus-host disease (GVHD) is the main cause of morbidity and mortality in allogeneic hematopoietic stem cell transplant survivors. Patients with acute and chronic GVHD often endure substantial symptom burden and quality of life (QOL) and functional impairments. Living with GVHD affects multiple domains of patient-reported QOL, physical functioning, and psychological well-being. Patients describe living with GVHD as a life-altering “full-time job” requiring unique knowledge, personal growth, and resilient coping strategies. Managing the supportive care needs of patients living with GVHD must include (1) monitoring of patient-reported QOL and symptom burden; (2) routine screening for psychological distress and implementing therapeutic strategies to treat depression, anxiety, and posttraumatic stress symptoms; (3) a systematic review of care needs by a multidisciplinary team experienced in managing transplant-related complications and organ-specific GVHD symptoms; and (4) ensuring optimal prevention and management of infection complications in this highly immunocompromised population. Improving the QOL in patients with GVHD requires a multidisciplinary approach with emphasis on aggressive symptom management, psychological coping, and promoting physical activity and rehabilitation in this population living with immense prognostic uncertainty and struggling to adapt to this difficult and unpredictable illness.
Impact of visceral fat on the prognosis of coronavirus disease 2019: an observational cohort study
Authors: Ogata Hiroaki , Mori Masahiro , Jingushi Yujiro , Matsuzaki Hiroshi , Katahira Katsuyuki , Ishimatsu Akiko , Enokizu-Ogawa Aimi , Taguchi Kazuhito , Moriwaki Atsushi , Yoshida Makoto
Published: December 2021

Background

Clarification of the risk factors for coronavirus disease 2019 (COVID-19) severity is strongly warranted for global health. Recent studies have indicated that elevated body mass index (BMI) is associated with unfavorable progression of COVID-19. This is assumed to be due to excessive deposition of visceral adipose tissue (VAT); however, the evidence investigating the association between intra-abdominal fat and COVID-19 prognosis is sparse. We therefore investigated whether measuring the amount of intra-abdominal fat is useful to predict the prognosis of COVID-19.

Methods

The present study enrolled 53 consecutive cases of COVID-19 patients aged ≥ 20 years with chest computed tomography (CT) scans. The VAT area, total adipose tissue (TAT) area, and VAT/TAT ratio were estimated using axial CT images at the level of the upper pole of the right kidney. Severe COVID-19 was defined as death or acute respiratory failure demanding oxygen at ≥ 6 L per minute, a high-flow nasal cannula, or mechanical ventilation. The association of VAT/TAT with the incidence of progression to a severe state was estimated as a hazard ratio (HR) using Cox regression analysis. To compare the prediction ability for COVID-19 disease progression between BMI and VAT/TAT, the area under the receiver operating characteristic curve (AUC) of each was assessed.

Results

A total of 15 cases (28.3% of the whole study subjects) progressed to severe stages. The incidence of developing severe COVID-19 increased significantly with VAT/TAT (HR per 1% increase = 1.040 (95% CI 1.008–1.074), P = 0.01). After adjustment for potential confounders, the positive association of VAT/TAT with COVID-19 aggravation remained significant (multivariable-adjusted HR = 1.055 (95% CI 1.000–1.112) per 1% increase, P = 0.049). The predictive ability of VAT/TAT for COVID-19 becoming severe was significantly better than that of BMI (AUC of 0.73 for VAT/TAT and 0.50 for BMI; P = 0.0495 for the difference).

Conclusions

A higher ratio of VAT/TAT was an independent risk factor for disease progression among COVID-19 patients. VAT/TAT was superior to BMI in predicting COVID-19 morbidity. COVID-19 patients with high VAT/TAT levels should be carefully observed as high-risk individuals for morbidity and mortality.
Anatomy and histomorphology of the flexor digitorum profundus enthesis: functional implications for tissue engineering and surgery
Authors: Mortimer Jeremy W. , Alsaykhan Hamad , Vadibeler Subashan , Rust Philippa A. , Paxton Jennifer Z.
Published: December 2021

Background

The enthesis possesses morphological adaptations across the soft-hard tissue junction which are not fully restored during surgical avulsion repairs. This loss of anatomical structure, highly related to function, contributes to poor clinical outcomes. Investigating the native macro- and micro-structure of a specific enthesis can provide functional and biomechanical insights to develop specialised, novel tissue-engineered therapeutic options and potentially improve current surgical treatments for avulsion injuries.

Methods

This study examines the anatomy and histomorphology of the flexor digitorum profundus (FDP) enthesis in 96 fresh-frozen human cadaveric fingers, quantitatively and qualitatively analyzing the shape, size, angle of tendon fibres and histological architecture, and explores differences in sex, finger and distance along the enthesis using linear mixed effects models.

Results

Macroscopically, results showed a consistent trapezoidal insertion shape of 29.29 ± 2.35 mm2 mean surface area, but with significant morphometric size differences influenced primarily by the smaller dimensions of the little finger. Microscopically, a fibrocartilaginous enthesis was apparent with a 30.05 ± 0.72o mean angle of inserting tendon fibres, although regional variation in fibrocartilage and the angle change of tendon fibres before insertion existed.

Conclusions

The implication of these findings on native and specific FDP enthesis function is discussed whilst providing recommendations for optimal FDP enthesis recreation for interfacial tissue engineers and hand surgeons. The study emphasizes the importance of region-specific knowledge whilst also describing methods applicable to assessing any soft tissue insertion.
Effects of intralesional pulsed radiofrequency treatment on pain in patients with calcaneal spur: results of 460 patients
Authors: Eke Ibrahim , Akcal Mehmet Akif , Sayrac Ali Vefa , Iyetin Yusuf
Published: December 2021

Background

This study aimed to investigate the efficacy of intralesional pulsed radiofrequency (RF) in the treatment of calcaneal spur and the results of patients who underwent single and double sessions of RF treatment.

Methods

The population of this retrospective study consisted of 460 patients who were diagnosed with calcaneal spur with clinical examination and direct radiography. The Wong-Baker Faces Pain Rating Scale and The American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score were used to determine the pain status and functional capacities of the patients. Posttreatment evaluation was carried out on average in the 6th week.

Results

The study involved 460 patients, 76.9% of whom were female, with the average age of 50.8 ± 10.9 years in total. Of the patients 43% was given RF therapy in a single session, and 57% of them in double sessions. After the RF procedure, the number of patients whose pain decreased according to both AOFAS and Wong-Baker pain scoring systems increased statistically significantly (p < 0.001). There was a statistically significant increase in the AOFAS-pain scores and the total AOFAS scores and a significant decrease in the Wong Baker-pain scale after treatment. However, there was no significant change in treatment success with respect to the number of RF sessions. Although not statistically significant, the differences in the AOFAS-pain scores and in the total AOFAS scores were found to be higher in patients who underwent single session RF, while the difference in the Wong Baker-pain ranking was higher in patients who received double sessions RF.

Conclusion

Intralesional pulsed RF procedure can be preferred as a relatively less invasive method that does not have any serious complications in patients with persistent calcaneal spurs who do not respond to the use of oral anti-inflammatory drugs and shoe insoles, nor corticosteroid injection to the lesion area.
The interaction between social factors and adversities on self-harm during the COVID-19 pandemic: longitudinal analysis of 49 227 UK adults
Authors: Paul Elise , Fancourt Daisy
Published: December 2021

Background

Little is known about which factors exacerbate and buffer the impact of coronavirus disease 2019 (COVID-19)-related adversities on changes in thinking about and engaging in self-harm over time.

Aims

To examine how changes in four social factors contribute to changes in self-harm thoughts and behaviours over time and how these factors in turn interact with adversities and worries about adversities to increase risk for these outcomes.

Method

Data from 49 227 UK adults in the UCL COVID-19 Social Study were analysed across the first 59 weeks of the pandemic. Fixed-effects logistic regressions examined time-varying associations between social support quality, loneliness, number of days of face-to-face contact for >15 min and number of days phoning/video calling for ≥15 min with self-harm thoughts and behaviours. We then examined how these four factors in turn interacted with the total number of adversities and worries about adversity and how this affected outcomes.

Results

Increases in the quality of social support were associated with decreases in the likelihood of both outcomes, whereas greater loneliness was associated with an increase in their likelihood. Associations were less clear for telephone/video contact and face-to-face contact with outcomes. Social support buffered and loneliness exacerbated the impact of adversity experiences on self-harm behaviours.

Conclusions

These findings suggest the importance of the quality of one's social support network, rather than the mere presence of contact, for reducing the likelihood of self-harm behaviours in the context of COVID-19 pandemic-related adversity and worry.
Οι τεχνολογίες πληροφορίας και επικοινωνιών στην εκπαίδευση ως γνωστικά εργαλεία
Authors: Μουράτογλου Νικόλαος
Published: December 2021

Ο σκοπός της παρούσας διατριβής αφορά στον έλεγχο επίδρασης της παρέμβασης της δεξιότητας τυφλής πληκτρολόγησης στην μεταγραφική και παραγωγική πληκτρολόγηση των μαθητών της Δ' τάξης Δημοτικού. Επιπλέον, διερευνήθηκε η συσχέτιση μεταξύ του μέσου μεταγραφής, της εργαζόμενης μνήμης και των κινήτρων με τη χειρόγραφη και την ψηφιακή παραγωγή λόγου των μαθητών. Δείγμα της οιονεί πειραματικής έρευνας αποτέλεσαν 43 μαθητές συγκροτώντας την πειραματική ομάδα, των οποίων οι επιδόσεις συγκρίθηκαν πριν και μετά από την παρέμβαση. Ειδικότερα, η παρέμβαση αξιοποίησε το λογισμικό RapidTyping, εφόσον προσαρμόστηκε στο γνωστικό επίπεδο των μαθητών, με στόχο την κατάκτηση της δεξιότητας της τυφλής πληκτρολόγησης. Τα ποσοτικά δεδομένα που συλλέχθηκαν περιλαμβάνουν τα χειρόγραφα και ψηφιακά κείμενα των μαθητών, δύο ερωτηματολόγια κινήτρων και μία συστοιχία έργων αξιολόγησης της εργαζόμενης μνήμης. Τα αποτελέσματα της έρευνας κατέδειξαν ότι η παρέμβαση ήταν αποτελεσματική ως προς την κατάκτηση της δεξιότητας, καθώς οι μαθητές βελτίωσαν την ταχύτητα και την ακρίβεια μεταγραφής τους, μειώνοντας περίπου κατά το ήμισυ τον απαιτούμενο χρόνο για την ολοκλήρωση της πληκτρολόγησης. Ακόμη, η παρούσα έρευνα κατέδειξε ότι η χρήση του υπολογιστή για την παραγωγή γραπτού λόγου μπορεί να μειώσει την επίδραση των έμφυλων διαφορών που εντοπίζονται μεταξύ των αγοριών και των κοριτσιών ως προς την ανάπτυξη των γραφοκινητικών τους δεξιοτήτων κατά την μεταγραφική πληκτρολόγηση, αλλά και να αμβλύνει τις διαφορές που εντοπίζονται ως προς την ποσότητα ψηφιακής παραγωγής λόγου μεταξύ των μαθητών με και χωρίς μαθησιακές δυσκολίες. Ως προς το μέσο παραγωγής, τα χειρόγραφα κείμενα των μαθητών ήταν εκτενέστερα και ποιοτικότερα συγκριτικά με τα ψηφιακά, ενώ ως προς την εργαζόμενη μνήμη διαπιστώθηκε ότι τα τρία υποσυστήματα της εργαζόμενης μνήμης επηρεάζουν και προβλέπουν σε σημαντικό βαθμό διάφορες πτυχές της της παραγωγικής διαδικασίας, όπως η ορθογραφία, η ποσότητα και η ταχύτητα πληκτρολόγησης. Ως προς τα κίνητρα των μαθητών, τα αποτελέσματα κατέδειξαν ισχυρή συσχέτιση και προβλεπτική ισχύ μεταξύ του ενδιαφέροντος για το έργο παραγωγής λόγου και της αντίληψης αυτοαποτελεσματικότητας των μαθητών, ενώ τα αυτόνομα κίνητρα των μαθητών συσχετίστηκαν θετικά με την ποιότητα παραγωγής λόγου και τα ελεγχόμενα κίνητρα με τα ορθογραφικά λάθη, υποδηλώνοντας ότι τα αυτόνομα κίνητρα συμβάλλουν θετικά στη μαθησιακή διαδικασία και τις επιδόσεις των μαθητών. Τέλος, η έρευνα συζητά τις παιδαγωγικές προεκτάσεις των ευρημάτων, επιδιώκοντας να ενισχύσει την πρακτική αξιοποίησή τους από ερευνητές και εκπαιδευτικούς.
Σύνθεση συμπλόκων ενώσεων και υλικών που προκύπτουν απο τετραθειομεταλλικά διανιόντα
Authors: Χαραλάμπους Ελένη
Published: December 2021

Η παρούσα διατριβή αναφέρεται στη σύνθεση νέων συμπλόκων ενώσεων και υλικών που προέρχονται από τετραθειομεταλλικά διανιόντα.Στο πρώτο μέρος παρουσιάζεται η σύνθεση και ο χαρακτηρισμός των μονοανιοντικών ετεροτριμεταλλικών συμπλόκων του τύπου [L2Rh(μ-S)2M(μ-S)2CuCl]- και των ετεροπενταμεταλλικών συμπλόκων [L2Rh(μ-S)2Μ(μ-S)2Ni(μ-S)2Μ(μ-S)2RhL2] (M = Mo, W). Το σύμπλοκο (NEt4)[(cis-dppen)Rh(μ-S)2W(μ-S)2CuCl]- χαρακτηρίστηκε με ανάλυση περίθλασης ακτίνων Χ. Έγινε υπολογιστική μελέτη (DFT) της ηλεκτρονικής δομής των συμπλόκων [(COD)Rh(μ-S)2M(μ-S)2CuCl]-, [(P(OMe)3)2Rh(μ-S)2M(μ-S)2CuCl]- και [(P(OMe)3)2Rh(μ-S)2M(μ-S)2Ni(μ-S)2M(μ-S)2Rh(P(OMe)3)2 (M = Mo, W), η οποία απεκάλυψε την ύπαρξη εκτεταμένου ηλεκτρονικού απεντοπισμού καθ’ όλη την έκταση των τετραμελών δακτυλίων Rh(μ-S)2M, M(μ-S)2Cu και M(μ-S)2Ni (M = Mo, W), και, συνεπώς, τη δυνατότητα ηλεκτρονικής επικοινωνίας μεταξύ των μεταλλικών κέντρων. Τα ηλεκτρονικά φάσματα των συμπλόκων αυτών μελετήθηκαν με υπολογισμούς TDDFT και η κύρια ταινία απορρόφησης στην ορατή περιοχή αποδόθηκε στην μετάπτωση μεταφοράς ηλεκτρονίου ν(Rh-->Mo/W). Επίσης, βρέθηκαν ενδιαφέρουσες συσχετίσεις των UV-vis και 31Ρ NMR πειραματικών δεδομένων με την ηλεκτρονική παράμετρο του Tolman (ΤΕΡ) και τις ηλεκτρονικές παραμέτρους της μεθόδου QALE, αντιστοίχως.Στο δεύτερο μέρος παρουσιάζεται η σύνθεση και μελέτη νέων άμορφων υλικών. Η αντίδραση των RhCl3 3H2O και (NH4)2MoS4 σε υδατικό διάλυμα σε αναλογία mol 2/3 οδηγεί στο σχηματισμό ενός μαύρου στερεού, από το οποίο προήλθαν δύο διαφορετικά προϊόντα ανάλογα με τον τρόπο θέρμανσής τους στους 150 οC. Η θέρμανσή του σε πυριατήριο, παρουσία ατμοσφαιρικού αέρα, ακολουθούμενη από εφαρμογή μηχανικής πίεσης 10 ton, σχηματίζεται το στερεό RM23SO4, ενώ με θέρμανση υπό κενό σχηματίζεται το στερεό RM23. Και τα δύο προϊόντα μελετήθηκαν με μετρήσεις FTIR, TEM, SEM, EDX, ΗRΤΕΜ και XPS. Tο RM23SO4 φαίνεται να αποτελείται από μίγμα οξο- και/ή οξοσουλφιδο- ενώσεων του μολυβδαινίου ή/και θειικού ροδίου, και το RM23 είναι ένα μίγμα οξειδίων και/ή σουλφιδίων μολυβδαινίου και ροδίου. Τέλος, διαπιστώθηκε ότι και τα δύο προϊόντα περιέχουν σημαντική ποσότητα άνθρακα, αν και δεν έχει χρησιμοποιηθεί αντιδραστήριο που περιέχει άνθρακα, πράγμα που σημαίνει ότι λαμβάνει χώρα δέσμευση CO2.
The Initial Analysis of the Share Suitability for the Inclusion into an Active Trading Strategy
Authors: Tolkachev I. , Kotov Aleksandr
Published: December 2021

The article lists the problems inherent to the Russian stock market at the present stage, special attention is paid to the liquidity issues. The authors evaluate the shares of all issuers listed on the Moscow Stock Exchange for the possibility of their inclusion in an active strategy based on average trading volumes. The article calculates the effectiveness of using the methods of average values in assessing the compliance of the selected instruments with the minimum required liquidity values. In the course of the work, the industry features of the Russian market are taken into account. The classifier of the Moscow Exchange is used to distribute issuers by industry. In parallel, the liquidity imbalance between the branches of the Russian stock market is being investigated. The conclusion is given about the real number of stock market instruments suitable for use in active trading strategies. The result of the study is a formed set of shares distributed by industry.
Rare health conditions 53: who cares for the caregiver?
Authors: Barber Chris
Published: December 2021

The purpose of this series is to highlight a range of rare health conditions. Rare health conditions are those that affect no more and usually fewer than one person in every 2000 and many healthcare assistants (HCAs) and nurses will encounter some of these conditions, given the high number of them. This 53rd article will explore the experiences of and challenges faced by informal caregivers of those with rare health conditions within a hospital setting and the roles of the HCA in supporting these caregivers.
Tackling workplace violence
Authors: Foster Sam
Published: December 2021

Sam Foster, Chief Nurse, Oxford University Hospitals, considers the problem of the harassment, abuse and violence towards NHS staff from patients and members of the public
CLOPIDOGREL
Authors: Rees Sharon
Published: December 2021

In this column, Sharon Rees aims to refresh knowledge and interest in some of the commonly used drugs in a series of tweets. This month she is talking about ##clopidogrel
COVID-19 booster vaccinations
Authors: Winter George
Published: December 2021

With the UK Health Security Agency announcement that those over 50 as well as health and social care workers are to be offered a COVID-19 vaccine boster, George Winter investigates whether research supports the necessity to do so
The role of bempedoic acid in the management of dyslipidaemia
Authors: Bostock Beverley
Published: December 2021

Bempedoic acid is a new oral lipid-lowering therapy which has been licenced for use in the United Kingdom. It can be used alone, with a statin, or with other lipid-lowering therapies where the target level for low density lipoprotein has not been achieved with these therapies alone. Bempedoic acid with ezetimibe can be prescribed for people who are unable to tolerate statins. This combination has received NICE approval following a technology appraisal. This paper discusses the place for of bempedoic acid as a lipid lowering drug and consider the mode of action, licensed indications, adverse drug reactions and the NICE technology appraisal recommendations.
December 2021 Pulmonary Case of the Month: Interstitial Lung Disease with Red Knuckles
Authors:   Arizona Chest and Sleep Medicine, Robbins Richard , Klotz Stephen
Published: December 2021

No abstract available. Article truncated after 150 words. We thought a follow-up to our original brief review of COVID-19 in February, 2020 might be useful. As we write this in early December 2021, we again caution that this area is rapidly changing and what is true today will likely be outdated tomorrow. We again borrowed heavily from the Centers for Disease Control (CDC) CDC website and the NIH website which have extensive discussions over numerous pages covering COVID-19. Our hope is to condense those recommendations. We do not discuss inpatient care in any detail. COVID-19 Variants The initial steps of coronavirus infection involve the specific binding of the coronavirus spike (S) protein to the cellular entry receptors which are normally on a cell. These include human aminopeptidase N (APN; HCoV-229E), angiotensin-converting enzyme 2 (ACE2; HCoV-NL63, SARS-CoV and SARS-CoV-2) and dipeptidyl peptidase 4 (DPP4; MERS-CoV). All viruses, but especially simple single-stranded RNA viruses like COVID-19, constantly change through mutation …
Correlation between acoustic divergence and phylogenetic distance in soniferous European gobiids (Gobiidae; Gobius lineage)
Authors: Horvatić Sven , Malavasi Stefano , Vukić Jasna , Šanda Radek , Marčić Zoran , Ćaleta Marko , Lorenzoni Massimo , Mustafić Perica , Buj Ivana , Onorato Lucija , Ivić Lucija , Cavraro Francesco , Zanella Davor
Published: December 2021

In fish, species identity can be encoded by sounds, which have been thoroughly investigated in European gobiids (Gobiidae, Gobius lineage). Recent evolutionary studies suggest that deterministic and/or stochastic forces could generate acoustic differences among related animal species, though this has not been investigated in any teleost group to date. In the present comparative study, we analysed the sounds from nine soniferous gobiids and quantitatively assessed their acoustic variability. Our interspecific acoustic study, incorporating for the first time the representative acoustic signals from the majority of soniferous gobiids, suggested that their sounds are truly species-specific (92% of sounds correctly classified into exact species) and each taxon possesses a unique set of spectro-temporal variables. In addition, we reconstructed phylogenetic relationships from a concatenated molecular dataset consisting of multiple molecular markers to track the evolution of acoustic signals in soniferous gobiids. The results of this study indicated that the genus Padogobius is polyphyletic, since P. nigricans was nested within the Ponto-Caspian clade, while the congeneric P. bonelli turned out to be a sister taxon to the remaining investigated soniferous species. Lastly, by extracting the acoustic and genetic distance matrices, sound variability and genetic distance were correlated for the first time to assess whether sound evolution follows a similar phylogenetic pattern. The positive correlation between the sound variability and genetic distance obtained here emphasizes that certain acoustic features from representative sounds could carry the phylogenetic signal in soniferous gobiids. Our study was the first attempt to evaluate the mutual relationship between acoustic variation and genetic divergence in any teleost fish.
Preliminary comparative study of cortical thickness in HIV-infected patients with and without working memory deficit
Authors: Cabral Rafael Ferracini , Corrêa Diogo Goulart , Zimmermann Nicolle , Tukamoto Gustavo , Kubo Tadeu Takao Almodovar , Fonseca Rochele Paz , Silva Marcos Martins , Wilner Nina Ventura , Bahia Paulo Roberto Valle , Gasparetto Emerson Leandro , Marchiori Edson
Published: December 2021

Purpose

Changes in cerebral cortical regions occur in HIV-infected patients, even in those with mild neurocognitive disorders. Working memory / attention is one of the most affected cognitive domain in these patients, worsening their quality of life. Our objective was to assess whether cortical thickness differs between HIV-infected patients with and without working memory deficit.

Methods

Forty-one adult HIV-infected patients with and without working memory deficit were imaged on a 1.5 T scanner. Working memory deficit was classified by composite Z scores for performance on the Digits and Letter-Number Sequencing subtests of the Wechsler Adult Intelligence Scale (third edition; WAIS-III). Cortical thickness was determined using FreeSurfer software. Differences in mean cortical thickness between groups, corrected for multiple comparisons using Monte-Carlo simulation, were examined using the query design estimate contrast tool of the FreeSurfer software.

Results

Greater cortical thickness in left pars opercularis of the inferior frontal gyrus, and rostral and caudal portions of the left middle frontal gyrus (cluster 1; p = .004), and left superior frontal gyrus (cluster 2; p = .004) was observed in HIV-infected patients with working memory deficit compared with those without such deficit. Negative correlations were found between WAIS-III–based Z scores and cortical thickness in the two clusters (cluster 1: ρ = –0.59; cluster 2: ρ = –0.47).

Conclusion

HIV-infected patients with working memory deficit have regions of greater thickness in the left frontal cortices compared with those without such deficit, which may reflect increased synaptic contacts and/or an inflammatory response related to the damage caused by HIV infection.
An evaluation of the evidence submitted to Australian alcohol advertising policy consultations
Authors: Stafford Julia , Chikritzhs Tanya , Pierce Hannah , Pettigrew Simone
Published: December 2021

Background

Industry self-regulation is the dominant approach to managing alcohol advertising in Australia and many other countries. There is a need to explore the barriers to government adoption of more effective regulatory approaches. This study examined relevance and quality features of evidence cited by industry and non-industry actors in their submissions to Australian alcohol advertising policy consultations.

Methods

Submissions to two public consultations with a primary focus on alcohol advertising policy were analysed. Submissions (n = 71) were classified into their actor type (industry or non-industry) and according to their expressed support for, or opposition to, increased regulation of alcohol advertising. Details of cited evidence were extracted and coded against a framework adapted from previous research (primary codes: subject matter relevance, type of publication, time since publication, and independence from industry). Evidence was also classified as featuring indicators of higher quality if it was either published in a peer-reviewed journal or academic source, published within 10 years of the consultation, and/or had no apparent industry connection.

Results

Almost two-thirds of submissions were from industry actors (n = 45 submissions from alcohol, advertising, or sporting industries). With few exceptions, industry actor submissions opposed increased regulation of alcohol advertising and non-industry actor submissions supported increased regulation. Industry actors cited substantially less evidence than non-industry actors, both per submission and in total. Only 27% of evidence cited by industry actors was highly relevant and featured at least two indicators of higher quality compared to 58% of evidence cited by non-industry actors.

Conclusions

Evaluation of the value of the evidentiary contribution of industry actors to consultations on alcohol advertising policy appears to be limited. Modifications to consultation processes, such as exclusion of industry actors, quality requirements for submitted evidence, minimum standards for referencing evidence, and requirements to declare potential conflicts, may improve the public health outcomes of policy consultations.
The risk of laryngitis with herpes zoster infection: A nested case-control study using data from the Korean National Sample Cohort
Authors: Joo Young-Hoon , Lee Hyun-Jin , Park Jun-Ook , Seo Young Joon , Kong Tae Hoon , Park Kyoung Ho
Published: December 2021

Background

Whether herpes zoster infection (HZI) affects laryngitis incidence remains unknown.

Objective

The purpose of this population-based retrospective study was to analyze the relationship between laryngitis and HZI using data from the Korean Health Insurance Review and Assessment Service—National Sample Cohort.

Methods

This study analyzed 1,197,093 medical claim codes from 2018. Patients with HZI (ICD-10: B02) were retrospectively identified. Laryngeal diseases were defined by ICD-10 codes for five subgroups: 1) malignant disease, 2) benign disease, 3) vocal cord palsy, 4) inflammatory disease, and 5) reflux disease.

Results

Among the Korean population older than 20 years, 12,809 experienced HZI. Subjects with HZI were more likely to be older (mean age: 51.54 years vs. 48.06 years, p <0.0001). The proportion of subjects with laryngeal disease was higher in those with HZI than in those without HZI (55.55% vs. 41.37%, p <0.0001). Laryngeal disease was significantly associated with HZI in multiple regression analysis (odds ratio (OR) = 1.77, 95% confidence interval: 1.71–1.84) after adjusting for age, sex, hypertension, diabetes, dyslipidemia, ischemic heart disease, cerebral stroke, and depression. Among laryngeal disease subgroups, inflammatory disease (OR = 1.05; 95% CI: 1.01–1.09) and reflux (OR = 1.20; 95% CI: 1.15–1.25) were associated with HZI.

Conclusions

HZI is independently associated with laryngitis. Results of this study have implications for etiological investigations and prevention strategies for laryngitis.
Faces places: Countermapping art, subalternities and counterpublics
Authors: Martinez Maria Simeona , Palis Joseph
Published: December 2021

This article is a critical reflection on our forays in the curatorial practice and exposition in March 2018 for a map art exhibit called Faces Places: Mapping Embodiments held at the University of the Philippines campus in Diliman. The exhibit was an exposition of different and alternative forms of mapping through the works of three Filipino artists: Mideo Cruz, Cian Dayrit and Mark Salvatus. We analysed their interventions in making visible the progressive geographies inherent in the everyday lifeworlds of Filipinos. Drawing from Nancy Fraser’s subaltern counterpublics, we argue that their artistic outputs are forms of counter-mapping vignettes that allow the possibility to illuminate the voices and habitus of the sifted and the excluded as new cartographical interventions intended for critical reflection and pedagogy. The art maps and countermaps of the artists evoked different responses that broadened and expanded understanding beyond what maps are, which allowed us to further interrogate the power structures that define world order through time. The production of new knowledges was derived not only from analysing the textual and symbolic aspects of the artistic countermaps but also with the processual aspect of art-making as emancipatory politics.
Espacios liminares: metamorfosis monstruosas de la casa en textos de Daína Chaviano y Mariana Enríquez
Authors: Díez Cobo Rosa María
Published: December 2021

El motivo de la casa encantada ha ganado gran visibilidad en los últimos tiempos en las literaturas de lo insólito en español. Concebida esta no solo como espacio anómalo, sino también como criatura fantástica, sus potenciales idiosincrasias arquitectónicas recrean en algunos textos territorios mutantes con notable impulso crítico y simbólico. Tomando como referencia las teorizaciones sobre el espacio fantástico y, en concreto, las enfocadas a sus fronteras y límites, en este trabajo se analizarán dos narrativas particularmente representativas: Casa de juegos (1999) de la cubana Daína Chaviano y Nuestra parte de noche (2019) de la argentina Mariana Enríquez. Este ejercicio comparativo pretende desvelar las similares estrategias de ambas autoras a la hora de forzar a sus protagonistas a penetrar en espacios heterotópicos, con sus propias normas y rituales. En los dos textos, además, verificaremos cómo sus casas protagonistas se conforman como trasunto de fenómenos históricos y sociales traumáticos y convulsos.
Ángel ESTEBAN (ed.). Literatura latinoamericana y otras artes en el siglo XXI. Bruselas: Peter Lang, 2021
Authors: Cuevas Velasco Norma Angélica
Published: December 2021

Reseña de Norma Cuevas sobre Literatura latinoamericana y otras artes en el siglo XXI.  (Peter Lang, 2020) de Ángel Esteban (ed). 368 p. ISBN: 978-2-8076-1286-0.    https://doi.org/10.3726/b17745
Análise da movimentação dos dentes artificiais em próteses totais superiores. Influência do tipo de polimento.
Authors: Goiato Marcelo C. , Vedovatto Eduardo , Amantéa Daniela C. Z. , G. Filho Humberto , Marinho Marcio L. V. D.
Published: December 2021

O propósito desse estudo foi o de verificar a influência do polimento sobre a posição relativa dos dentes artificiais de próteses totais superiores, quando essas são confeccionadas com diferentes tipos de materiais ou associações, analisando para tanto à diferença entre as distâncias dos dentes pelo método de computação gráfica. Foram confeccionadas quarenta próteses totais superiores idênticas, sendo divididas em oito grupos de cinco espécimes cada de acordo com o tipo de resina (Vipi-wave e Onda-cryl), tipo de silicone para inclusão (Vipi-sil e Zetalabor) e tipo de polimento. As próteses foram polimerizadas em microondas, demufladas e submetidas ao polimento químico e ao polimento mecânico. Em cada fase as próteses foram digitalizadas em scanner de mesa e suas imagens exportadas para o software AutoCad 2000 que possibilitou a mensuração dos segmentos entre os pontos previamente demarcados nos dentes. Os dados foram submetidos ao tratamento estatístico, e os resultados possibilitaram concluir que o polimento físico resultou em alterações significantemente superiores ao polimento químico quando os dados foram analisados independentemente do grupo estudado (p<0,05). O polimento das próteses resultou na grande maioria das amostras em uma recuperação gradual da contração de polimerização. Os grupos em que a resina de eleição foi a Vipi-wave (T1, T1’, T2 e T2’) apresentaram-se menos susceptível ao polimento químico que os grupos em que a resina foi a Onda-cryl (T3, T3’, T4 e T4’).
Cianoacrilato como protetor superficial de restauração de cimento de óxido de zinco e eugenol e de cimento de ionômero de vidro: avaliação da infiltração marginal
Authors: P. Souza Fernanda C. P. , Contente Marta M. M. G. , Casemiro Luciana A.
Published: December 2021

O objetivo deste trabalho foi avaliar a infiltração marginal em restaurações de cimento de óxido de zinco e eugenol e cimento de ionômero de vidro com e sem a utilização de um selante de superfície à base de cianoacrilato. Trinta dentes posteriores foram restaurados com cimento de óxido de zinco e eugenol, OZE, (15) ou com cimento de ionômero de vidro, CIV, (15). Para cada material, os dentes foram divididos em grupo controle (5), proteção superficial com cianoacrilato precedida de ataque ácido (5) e proteção superficial com cianoacrilato sem ataque ácido. Após ensaio de termociclagem, as superfícies radiculares dos dentes foram isoladas com Araldite® e as amostras imersas em solução corante Rodamina B 0,2%. As amostras foram acondicionadas em estufa a 37ºC por 24 horas e, a seguir, removidas da solução corante e lavadas em água corrente. Os dentes foram embutidos em resina de poliéster e cortados no sentido mésio-distal em seu longo eixo. O grau de penetração marginal foi avaliado por meio de microscopia óptica segundo escore previamente definido e os resultados obtidos analisados estatisticamente (Kruskal-Wallis p<0.05). As restaurações de OZE apresentaram infiltração marginal reduzida quando submetidas à proteção superficial com cianoacrilato após realização do ataque ácido. O cianoacrilato não reduziu a infiltração marginal das restaurações de CIV (Apoio PIBIC/CNPq).
Estudo do efeito do plumbum metallicum 30ch na reparação óssea em mandíbulas de ratos sem barreira mecânica
Authors: Almeida Janete Dias de , Arisawa Emília Ângela L. , Lima Ana Paula , Rocha Rosilene F. , Carvalho Yasmin R.
Published: December 2021

Objetivos: O objetivo deste trabalho foi avaliar os efeitos da administração sistêmica do chumbo, preparado de acordo com a farmacotécnica homeopática Plumbum metallicum 30CH, na reparação óssea. Material e métodos: foram utilizados trinta ratos machos com três meses de idade, nos quais foram confeccionados defeitos cirúrgicos trans-ósseos com broca de aço nº 06 na região do ângulo da mandíbula do lado direito, sem utilização de barreira mecânica. Cada animal do grupo experimental recebeu três gotas diárias de Plumbum metallicum 30CH acrescidas à mamadeira de água. Os animais do grupo controle receberam apenas água. Três animais foram sacrificados nos seguintes períodos experimentais: um, sete, 14, 21 e 28 dias após a cirurgia. Após o sacrifício, as mandíbulas foram removidas, descalcificadas e submetidas ao preparo histológico de rotina. Foram submetidas a cortes semi-seriados e coradas pelos métodos de hematoxilina-eosina e tricômico de Masson para análise histológica em microscópio de luz. Resultados: os resultados obtidos neste trabalho mostraram que o medicamento foi eficiente na estimulação da reparação óssea. A análise histológica qualitativa mostrou evidência de efeito favorável do Plumbum mettalicum 30 CH. Apesar da interferência do tecido muscular, os animais mostraram, já a partir do período de 14 dias, neoformação óssea em praticamente toda a extensão do defeito. Conclusão: a utilização do Plumbum metallicum 30CH favoreceu a reparação de defeitos ósseos em mandíbula de ratos machos, sem a utilização de barreira mecânica.
Evaluation of the methods used for impression making for different implant systems in prosthetic dentistry
Authors: Özkan Yasar , Özcan Mutlu , Akalin Fidan , Kulak-Özkan Yasemin , Valandro Luiz Felipe , Faria Renata
Published: December 2021

Fabrication of an implant supported fixed or removable-partial-denture requires precise transfer of the intraoral structures and the implant components to the plaster model. With the increase in the number of implant systems, impression making procedures also increased depending on each system. This article summarizes and describes the procedures and factors that affect adequate impression making for several implant systems based on the information from English peer-reviewed journals identified by a Medline search covering the years from 1979-2005, text books, and the information obtained from the manufacturers of the most commonly used implant systems.Clinical relevance: since impression making methods vary depending on each implant system, clinicians should study the procedures for each system in order to achieve successful implant supported fixed- or removable-partial-dentures.