bluuebunny/crossref_metadata_2025 huggingface dataset:
A molecular precursor route to quaternary chalcogenide CFTS (Cu2FeSnS4) powders as potential solar absorber materials
Authors: Alanazi Abdulaziz M. , Alam Firoz , Salhi Abdelmajid , Missous Mohamed , Thomas Andrew G. , O'Brien Paul , Lewis David J.
Published: August 2019

In the present work we report on the synthesis of a tetragonal phase of stannite Cu2FeSnS4powder from Sn(ii) and Sn(iv) using a solvent free melt method using a mixture of Cu, Fe, Sn(ii)/Sn(iv)O-ethylxanthates.
Additive effects of alkali metals on Cu-modified CH3NH3PbI3−δClδphotovoltaic devices
Authors: Ueoka Naoki , Oku Takeo , Suzuki Atsushi
Published: August 2019

Addition of alkali metal elements (Na+, K+, Rb+, and Cs+) to Cu-modified CH3NH3PbI3−δClδdevices improved the photovoltaic properties.
Innovative flat-plate solar collector (FPC) with coloured water flowing through a transparent tube
Authors: Kim Sedong , Jeong Hyomin , Park Jin Young , Baek Seung Yeop , Lee Ajeong , Choi Soon-Ho
Published: August 2019

Light absorption rates depends on the color of a substance. In this study, a new type of FPC was suggested, which utilizes the light absorption rate of the working fluid passing through a transparent collecting tube.
Enhancing the photo-efficacy of an organic visible-light-activated chromophore (alizarin red S) on zinc oxide with a Ag–Na electrolyte to photo-transform aromatic and aliphatic alcohols
Authors: Underwood Timothy M. , Robinson Ross S.
Published: August 2019

An in-depth analysis into a dye-sensitised metal oxide system through photo-mechanical studies has extended the knowledge basis of semiconductor-mediated photocatalysis.
Exhaustive exploration of the conformational landscape of mono- and disubstituted five-membered rings by DFT and MP2 calculations
Authors: Stortz Carlos A. , Sarotti Ariel M.
Published: August 2019

The conformational landscape of 22 different non, mono-, and disubstituted compounds with a five-membered ring was thoroughly explored by ab initio (MP2) and DFT (B3LYP and M06-2X) methods with the 6-311+G** basis set.
Thermosensitive double network of zwitterionic polymers for controlled mechanical strength of hydrogels
Authors: Hsu Wei-Hsin , Kao Yu-Chih , Chuang Shun-Hao , Wang Jun-Sheng , Lai Juin-Yih , Tsai Hsieh-Chih
Published: August 2019

Zwitterionic hydrogels have promising anti-fouling properties but weak mechanical strength. Here, we synthesized two polyzwitterions, formulated them as double network hydrogels for improving strength and for controlled by temperature stimuli.
Facile synthesis of few-layer MoS2 in MgAl-LDH layers for enhanced visible-light photocatalytic activity
Authors: Zheng Guoyuan , Wu Caihong , Wang Jilin , Mo Shuyi , Wang Yanwu , Zou Zhengguang , Zhou Bing , Long Fei
Published: August 2019

Few-layer MoS2 was successfully grown in MgAl-LDH layers, utilizing the “space-confining” effect. The composite completed degraded 50 mg L−1 and 100 mg L−1 methyl orange (MO) solutions in 45 min and 105 min, respectively.
Novel biodegradable and non-fouling systems for controlled-release based on poly(ε-caprolactone)/Quercetin blends and biomimetic bacterial S-layer coatings
Authors: Sanchez-Rexach Eva , Iturri Jagoba , Fernandez Jorge , Meaurio Emilio , Toca-Herrera Jose-Luis , Sarasua Jose-Ramon
Published: August 2019

S-Layer coating on PCL–Quercetin miscible blends acts as a release controller from films and scaffolds, as well as antifouling agent.
Dispersion of microcapsules for the improved thermochromic performance of smart coatings
Authors: Pedaballi Sireesha , Li Chia-Chen , Song Ya-Jun
Published: August 2019

Efficient dispersant that can well disperse and enhance the physical performance of thermochromic microcapsules is proposed.
Highly efficient crystallization of AlPO4-5 accelerated by a rotating hydrothermal synthesis route
Authors: Xia Kun , He Zhechao , Zhou Dan , Lu Xinhuan , Xia Qinghua
Published: August 2019

Rapid crystallization of AlPO4-5 accelerated by rotation accompanied by the conversion from five-coordinated Al to four-coordinated Al.
Selective synthesis of azoxybenzenes from nitrobenzenes by visible light irradiation under continuous flow conditions
Authors: Nishiyama Yasuhiro , Fujii Akira , Mori Hajime
Published: August 2019

Herein we report a highly selective preparation method of azoxybenzenes from nitrobenzenes by visible-light irradiation using flow microreactors.
Boronate affinity-based photoactivatable magnetic nanoparticles for the oriented and irreversible conjugation of Fc-fused lectins and antibodies
Authors: Fan Chen-Yo , Hou Yi-Ren , Adak Avijit K. , Waniwan Juanilita T. , dela Rosa Mira Anne C. , Low Penk Yeir , Angata Takashi , Hwang Kuo-Chu , Chen Yu-Ju , Lin Chun-Cheng
Published: August 2019

A combination of boronic acid and a photoactivatable diazirine enables oriented conjugation of Fc-fused lectins and antibodies on nanoparticles.
Machine learning enables long time scale molecular photodynamics simulations
Authors: Westermayr Julia , Gastegger Michael , Menger Maximilian F. S. J. , Mai Sebastian , González Leticia , Marquetand Philipp
Published: August 2019

Machine learning enables excited-state molecular dynamics simulations including nonadiabatic couplings on nanosecond time scales.
Selective single C–F bond arylation of trifluoromethylalkene derivatives
Authors: Tang Luning , Liu Ze-Yao , She Wenzhi , Feng Chao
Published: August 2019

Through an SN2′ amination, N-alkylation and palladium-catalyzed allylic substitution sequence, we realized ipso-C–F bond arylation/alkenylation of trifluoromethylalkene derivatives.
Benchmark selectivity p-xylene separation by a non-porous molecular solid through liquid or vapor extraction
Authors: Sun Na , Wang Shi-Qiang , Zou Ruqiang , Cui Wen-Gang , Zhang Anqi , Zhang Tianzhen , Li Qi , Zhuang Zhan-Zhong , Zhang Ying-Hui , Xu Jialiang , Zaworotko Michael J. , Bu Xian-He
Published: August 2019

Solid–liquid separation of similarly sized organic molecules utilizing sorbents offers the potential for new energy-efficient approaches to a number of important industrial separations such as xylenes (C8) separations.
Reversible nanocluster structure transformation between face-centered cubic and icosahedral isomers
Authors: Kang Xi , Huang Li , Liu Wei , Xiong Lin , Pei Yong , Sun Zhihu , Wang Shuxin , Wei Shiqiang , Zhu Manzhou
Published: August 2019

The reversible transformation between a FCC and icosahedral configuration has been achieved at the atomic level, based on Pt1Ag28 nanocluster isomers.
Photoredox-catalyzed stereoselective alkylation of enamides with N-hydroxyphthalimide esters via decarboxylative cross-coupling reactions
Authors: Guo Jing-Yu , Zhang Ze-Yu , Guan Ting , Mao Lei-Wen , Ban Qian , Zhao Kai , Loh Teck-Peng
Published: August 2019

Stereoselective β-C(sp2)–H alkylation of enamides with N-hydroxyphthalimide esters is demonstrated, affording geometrically defined alkylated enamides bearing various functional groups.
Multifunctional pyrazoline based AIEgens: real-time tracking and specific protein “fishing” of lipid droplets
Authors: Zhao Na , Li Yan , Yang Weiyao , Zhuang Jiabao , Li Yue , Li Nan
Published: August 2019

A series of multifunctional pyrazoline based AIEgens were developed for real-time tracking of lipid metabolism, reversibly monitoring intracellular pH in dual-color mode and specific labeling of lipid droplet related protein.
A Cu–Pd single-atom alloy catalyst for highly efficient NO reduction
Authors: Xing Feilong , Jeon Jaewan , Toyao Takashi , Shimizu Ken-ichi , Furukawa Shinya
Published: August 2019

Highly active and selective NO reduction was achieved at low temperatures using a minimum amount of noble metal Pd.
Direct use of biomass powder in internal combustion engines
Authors: Stover L. , Piriou B. , Caillol C. , Higelin P. , Proust C. , Rouau X. , Vaïtilingom G.
Published: August 2019

A first general assessment of the biomass dust-fuelled engine concept by testing four biomass powders in a single-cylinder engine.
Diperovskite (NH4)3FeF6/graphene nanocomposites for superior Na-ion storage
Authors: Hao Zhanghui , Fuji Masayoshi , Zhou Jisheng
Published: August 2019

Diperovskite (NH4)3FeF6/graphene nanocomposites were synthesized using a co-pyrolysis approach and exhibited superior rate performance and cycling stability for Na ion storage.
Structure, dynamics and phase behavior of short rod inclusions dissolved in a colloidal membrane
Authors: Siavashpouri Mahsa , Sharma Prerna , Fung Jerome , Hagan Michael F. , Dogic Zvonimir
Published: August 2019

Short-rod inclusions dissolved in an anisotropic quasi-2D colloidal membrane anchor to the membrane-polymer interface and acquire new types of interactions that drive bulk phase separation and assembly of complex structures and patterns.
A template-directed bifunctional NiSx/nitrogen-doped mesoporous carbon electrocatalyst for rechargeable Zn–air batteries
Authors: Wan Kai , Luo Jiangshui , Zhang Xuan , Zhou Chen , Seo Jin Won , Subramanian Palaniappan , Yan Jia-wei , Fransaer Jan
Published: August 2019

A highly ordered mesoporous NiSx/nitrogen-doped mesoporous carbon (NiSx/NMC) nanohybrid as a bifunctional oxygen electrocatalyst for rechargeable Zn–air batteries.
Scalable synthesis of dispersible iron carbide (Fe3C) nanoparticles by ‘nanocasting’
Authors: Fletcher D. C. , Hunter R. , Xia W. , Smales G. J. , Pauw B. R. , Blackburn E. , Kulak A. , Xin Huolin , Schnepp Z.
Published: August 2019

MgO powder is used as a removable ‘cast’ in a simple, scalable synthesis of dispersible Fe3C nanoparticles.
Light-induced electrolyte improvement in cobalt tris(bipyridine)-mediated dye-sensitized solar cells
Authors: Gao Jiajia , Yang Wenxing , El-Zohry Ahmed M. , Prajapati Govind Kumar , Fang Yuan , Dai Jing , Hao Yan , Leandri Valentina , Svensson Per H. , Furó István , Boschloo Gerrit , Lund Torben , Kloo Lars
Published: August 2019

We observe a light-induced performance improvement in Co(ii/iii)-mediated DSSCs, and attribute this to an irreversible light effect on the electrolyte system containing Co(iii) together with tert-butylpyridine (TBP).
Designing π-conjugated polymer blends with improved thermoelectric power factors
Authors: Abtahi Ashkan , Johnson Stephen , Park So Min , Luo Xuyi , Liang Zhiming , Mei Jianguo , Graham Kenneth R.
Published: August 2019

Blending two or more π-conjugated polymers together provides a means of manipulating charge transport properties and potentially improving the performance of organic thermoelectrics.
Bioinspired enamel-like oriented minerals on general surfaces: towards improved mechanical properties
Authors: Chen Zhuoxin , Miao Zhangshu , Zhang Pan , Xiao Hong , Liu Huan , Ding Chunmei , Tan Hong , Li Jianshu
Published: August 2019

Enamel-like oriented hydroxyapatite minerals were obtained on general surfaces by a biomimetic, anodic alumina oxide (AAO)-assisted, double-layered gel system.
High unsaturated room-temperature magnetoresistance in phase-engineered MoxW1−xTe2+δultrathin films
Authors: Mathew Roshan Jesus , Inbaraj Christy Roshini Paul , Sankar Raman , Hudie Shemsia Mohammed , Nikam Revannath Dnyandeo , Tseng Chi-Ang , Lee Chih-Hao , Chen Yit-Tsong
Published: August 2019

UltrathinTd-Mo0.27W0.71Te2.02films synthesized using a chemical vapor deposition method exhibit a non-saturating magnetoresistance of 11% at room temperature.
Methylamine-induced defect-healing and cationic substitution: a new method for low-defect perovskite thin films and solar cells
Authors: Yang Jin-an , Qin Tianxu , Xie Lisha , Liao Kejun , Li Tingshuai , Hao Feng
Published: August 2019

Methylamine-induced defect-healing and cationic substitution was reviewed for low defect perovskite films with better crystal quality and high stability.
Bandgap-tunable phosphorus-doped monolayer graphene with enhanced visible-light photocatalytic H2-production activity
Authors: Wu Yujun , Cao Chuanbao , Qiao Chen , Wu Yu , Yang Lifen , Younas Waqar
Published: August 2019

Graphene-based materials hold great promise in future applications due to their phenomenal properties; however, the lack of a suitable bandgap severely limits their practical applications.
High-efficiency pure blue thermally activated delayed fluorescence emitters with a preferentially horizontal emitting dipole orientation via a spiro-linked double D–A molecular architecture
Authors: Zeng Xuan , Pan Kuan-Chung , Lee Wei-Kai , Gong Shaolong , Ni Fan , Xiao Xiao , Zeng Weixuan , Xiang Yepeng , Zhan Lisi , Zhang Yu , Wu Chung-Chih , Yang Chuluo
Published: August 2019

A spiro-linked double D–A molecular architecture has been introduced to construct blue thermally activated delayed fluorescence (TADF) emitters with a preferentially horizontal emitting dipole orientation.
Does miR-618 rs2682818 variant affect cancer susceptibility? Evidence from 10 case–control studies
Authors: Feng Xingliang , Ji Dan , Liang Chaozhao , Fan Song
Published: August 2019

Piles of evidence have supported the relationship between miR-618 rs2682818 polymorphism and tumorigenesis, but the conclusion remains inconsistent. In the present study, we conducted a meta-analysis to sniff out the potential risk between miR-618 rs2682818 and overall cancers. Crude odds ratios (ORs) and 95% confidence intervals (CIs) analyzed by Z-test were employed to estimate the potential interrelation in five genetic models. We also prospected how the rs2682818 affects the second structure of miR-618. Finally, 10 independent studies meet the enrolled criteria, along with 4099 cancer cases and 5057 healthy controls. Overall, no exceeding interrelation was sniffed out in the pooled data among five inherited models, as well as stratified analyses. Whereas, the enhanced cancer risk of miR-618 rs2682818 variant stratified by breast cancer was revealed, in heterozygote genetic model (AC vs. CC: OR = 1.291, 95%CI = 1.012–1.648, P = 0.040) and dominant contrast model (AA + AC vs. CC: OR = 1.280, 95%CI = 1.009–1.623, P = 0.042). The second structure prediction result shown that the mutant A allele might change the first stem-loop of miR-618, and the free energy of it would turn from –39.1 to –35.1 kcal/mol. All in all, our meta-analysis had successfully chased down that miR-618 rs2682818 polymorphism is not linked with overall cancer risk, but in the dominant genotype of breast cancer.
Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition
Authors: Yuan Yujia , Chen Younan , Peng Tianqing , Li Lan , Zhu Wuzheng , Liu Fei , Liu Shuyun , An Xingxing , Luo Ruixi , Cheng Jingqiu , Liu Jingping , Lu Yanrong
Published: August 2019

Macrophage polarization toward the M1 phenotype and its subsequent inflammatory response have been implicated in the progression of diabetic complications. Despite adverse consequences of autophagy impairment on macrophage inflammation, the regulation of macrophage autophagy under hyperglycemic conditions is incompletely understood. Here, we report that the autophagy–lysosome system and mitochondrial function are impaired in streptozotocin (STZ)-induced diabetic mice and high glucose (HG)-stimulated RAW 264.7 cells. Mitochondrial dysfunction promotes reactive oxygen species (ROS) production and blocks autophagic flux by impairing lysosome function in macrophages under hyperglycemic conditions. Conversely, inhibition of mitochondrial ROS by Mito-TEMPO prevents HG-induced M1 macrophage polarization, and its effect is offset by blocking autophagic flux. The role of mitochondrial ROS in lysosome dysfunction and M1 macrophage polarization is also demonstrated in mitochondrial complex I defective RAW 264.7 cells induced by silencing NADH:ubiquinone oxidoreductase subunit-S4 (Ndufs4). These findings prove that mitochondrial ROS plays a key role in promoting macrophage polarization to inflammatory phenotype by impairing autophagy–lysosome system, which might provide clue to a novel treatment for diabetic complications.
ALMA resolves the hourglass magnetic field in G31.41+0.31
Authors: Beltrán M. T. , Padovani M. , Girart J. M. , Galli D. , Cesaroni R. , Paladino R. , Anglada G. , Estalella R. , Osorio M. , Rao R. , Sánchez-Monge Á. , Zhang Q.
Published: August 2019

Context. Submillimeter Array (SMA) 870 μm polarization observations of the hot molecular core G31.41+0.31 revealed one of the clearest examples up to date of an hourglass-shaped magnetic field morphology in a high-mass star-forming region.

Aims. To better establish the role that the magnetic field plays in the collapse of G31.41+0.31, we carried out Atacama Large Millimeter/ submillimeter Array (ALMA) observations of the polarized dust continuum emission at 1.3 mm with an angular resolution four times higher than that of the previous (sub)millimeter observations to achieve an unprecedented image of the magnetic field morphology.

Methods. We used ALMA to perform full polarization observations at 233 GHz (Band 6). The resulting synthesized beam is 0′′.28×0′′.20 which, at the distance of the source, corresponds to a spatial resolution of ~875 au.

Results. The observations resolve the structure of the magnetic field in G31.41+0.31 and allow us to study the field in detail. The polarized emission in the Main core of G31.41+0.41is successfully fit with a semi-analytical magnetostatic model of a toroid supported by magnetic fields. The best fit model suggests that the magnetic field is well represented by a poloidal field with a possible contribution of a toroidal component of ~10% of the poloidal component, oriented southeast to northwest at approximately −44° and with an inclination of approximately −45°. The magnetic field is oriented perpendicular to the northeast to southwest velocity gradient detected in this core on scales from 103 to 104 au. This supports the hypothesis that the velocity gradient is due to rotation of the core and suggests that such a rotation has little effect on the magnetic field. The strength of the magnetic field estimated in the central region of the core with the Davis–Chandrasekhar-Fermi method is ~8–13 mG and implies that the mass-to-flux ratio in this region is slightly supercritical.

Conclusions. The magnetic field in G31.41+0.31 maintains an hourglass-shaped morphology down to scales of <1000 au. Despite the magnetic field being important in G31.41+0.31, it is not enough to prevent fragmentation and collapse of the core, as demonstrated by the presence of at least four sources embedded in the center of the core.
Autopilot Structured H∞ Synthesis for Satisfying Gain and Phase Margin Constraints
Authors: Ma Xiaochuan , Yan Jie , Fu Wenxing , Chen Kang
Published: August 2019

Aiming at the static unstable Hypersonic vehicle, a method for designing H∞ autopilot to satisfy gain margin and phase margin is proposed. Structured H∞ synthesis is used to synthesize the autopilot under the fixed structure. The gain margin and phase margin were constrained by using H∞ norm of the complementary of the scaled plant. The requirement for the gain margin and phase margin is represented by the distance between the open loop Nyquist curve and the circle that represents the gain margin and phase margin in the complex plane. The distance is adjusted by tuning the parameter of performance specifications automatically to reduce the conservatism of the controller. The present method is applicable to both static stable vehicle and static unstable vehicle, and a three loops acceleration tracking autopilot is design. The numerical simulations have demonstrated that the autopilot satisfys the performance specifications, gain margin and phase margin simultaneously.
Sinking Velocity Compact-Analysis of Carrier-Based Aircraft Based on Improved Kriging Model
Authors: Xue Xiaofeng , Wang Yuanzhuo , Lu Cheng
Published: August 2019

The sinking velocity of carrier-based aircraft is an important input for landing gear design, and has a great influence on the weight of the landing gear and airframe structure. Aiming at exploring the effect of the various related landing parameters on the sinking velocity for carrier-based aircraft at the actual service environment, and based on F/A-18A measured landing data, the correlation degree between 15 landing parameters and sinking velocity is analyzed by partial correlation analysis method in multivariate statistics. The results show that the aircraft instantaneous gliding angle and deck pitch angle are highly correlated with the sinking velocity, the approach velocity and the engaging velocity are moderately correlated with the sinking velocity. The above four parameters are used as the independent variables, an improved Kriging surrogate model for the sinking velocity of F/A-18A aircraft is established, and Genetic algorithm is used to optimize the undetermined coefficients of correlation functions. The complex correlation coefficient of the sinking velocity predicted by the proposed model is 0.981, the average relative error is 1.813% and the maximum relative error is 6.771%. And comparing the empirical formula with the ordinary Kriging model, the precision index is the best. The proposed model provides the best prediction results. The improved Kriging surrogate model and the results obtained in this paper can provide a basis for studying the sinking velocity and controlling landing attitude for similar models carrier-based aircraft.
Uncontrolled Generation Analysis and System Optimization of Permanent Magnet Synchronous Motor for Electric Vehicle
Authors: Zhang Liao , Gong Chao , Liu Jinglin
Published: August 2019

When a permanent magnet synchronous motor(PMSM) which is controlled by flux-weakening strategy rotates in high speed, the controller would send the turning-off signals to switch off all the transistors quickly if faults(e.g. overvoltage and overcurrent) occur. At this moment, the equivalent electromotive force is higher than battery voltage due to the high speed of motor, so the current flows into the battery through the uncontrolled rectifier bridge composed of six freewheeling diodes, resulting in the drive system works at the status of uncontrolled generation(UCG). Firstly, the mathematical model of the system is established. Then, according to the theoretical analysis, the UCG process is divided into three stages: transistors turning-off stage, diodes freewheeling and turning-on stage and steady-state UCG stage. It is found that the steady-state UCG process has the shortcomings of large current and long time. Therefore, an optimal protection scheme based on fuzzy control is proposed, which can reduce danger damage of UCG. Finally, simulation and experiment are adopted to study the process of UCG, and the effectiveness of the optimization strategy is verified.
Integrated Guidance and Control of Multiple Interceptors with Impact Angle Constraints Considered
Authors: Liu Xiang , Liang Xiaogeng
Published: August 2019

To solve the multi-interceptor coordination problem and to intercept the target with impact angle constraint, a novel distributed cooperative control algorithm with impact angle constraint based on integrated guidance and control is proposed. First, the mathematic model of integrated guidance and control is established by combining the interceptor-target relative motion model with the dynamic equation of the interceptor on pitch plane. The time varying gain extended state observer is developed to estimate and compensate the unknown disturbance. Based on the estimated value and fast nonsingular dynamic surface sliding control method, the IGC algorithm of leader is given; Then, based on distributed cooperative "leader-follower" model, the cooperative control strategy of multi-interceptor is designed, and gives out speeds in two directions on pitch plane, which are transformed to the command of total velocity and trajectory angle based on kinematic relations. Finally, to control the follower, the time varying gain extended state observer and the dynamic surface sliding control method are adopted. The simulation results demonstrate the effectiveness of the distributed cooperative control algorithm.
Design of Magnetic Field LUT Model for Femto-Satellites
Authors: Liu Yong , Liu Kunpeng , Hou Xiaolei , Pan Quan , Zhang Jun
Published: August 2019

Aiming at the high computational complexity and large storage of IGRF geomagnetic field model in Attitude Determination and Control System (ADCS), the uniform sampling model and K-Curvature weighted model have been established. First of all, storage format and track deduction method of uniform look-out-table (LUT) model is proposed. Then, this paper uses U-Discrete curvature calculation method to solve the discrete curvature of magnetic field data. Finally, the uniform sampling method and K-Curvature Weighted model in fitting the original curve has been compared. In general, this paper presents K curvature weighted non-uniform LUT model with only 80 points needed, and it only needs 0.96 kB. It proves great advantages in terms of computing speed and storage space compared with the existing technology.
LDPC Decoder of High Speed Multi-Rate DVB-S2 Based on FPGA
Authors: Xie TianJiao , Li Bo , Yang Mao , Yan Zhongjiang
Published: August 2019

A multi-rate LDPC decoder architecture for DVB-S2 codes based on FPGA is proposed. Through elementary transformation on the parity check matrices of DVB-S2 LDPC codes, a new matrix whose left is a QC sub-matrix and right is Transformation of Staircase lower triangular (TST) sub-matrix is obtained. The QC and TST are designed separately, therefore the successful experience of the most popular Quasi-Cyclic (QC) LDPC decoder architecture can be drawn on. While for TST sub-matrix, the variable nodes updating only need to be considered and the check nodes updating is realized compatibility with QC sub-matrix. Based on the proposed architectures, a multi-rate LDPC decoder implemented on Xilinx XC7VX485T FPGA can achieve the maximum decoding throughput of 2.5 Gbit/s at the 20 iterations when the operating frequency is 250 MHz, which demonstrates the highest throughput compared with the state-of-the-art works.
Aerodynamic Layout Designs Using of Microflaps for Flow Control of a Supersonic Finned Projectile
Authors: Li Xiaopeng , Kang Shun , Wang Tianming , Zhao Yangzheng
Published: August 2019

In this paper, the flow control system consists of some small microflaps located between the rear fins of the projectile. These microflaps can alter the flow field in the finned region of the projectile resulting in asymmetric pressure distribution and thus producing control forces and moments, furthermore to provide directional control for a supersonic projectile. Due to the small size and high speed characteristics of projectile, which is with fast and valid response characteristics, this flow control system has initially shown excellent potential in terms of supersonic flow control. The CFD simulation used here solves steady-state Reynolds-averaged Navier-Stokes equation with two-equation turbulence model k-ε. Firstly, we investigate the flow mechanism around microflap in supersonic flow, the flow fields around the microflap are complex, involving three-dimensional shock-shock, shock-boundary layer interactions. Secondly, for the microflap and the fin of Basic Finner configuration, the influence of microflap geometric parameters, microflap locations on aerodynamics is obtained and the interference mechanism is explored. Finally, several typical roll and pitch control layouts are described. According to the simulation results and their analysis, some preliminary conclusions can be drawn: by analyzing the flow interference mechanism between microflap and the fin, we find that the separated shocks ahead of the microflap, the bow shocks around microflap, and the trailing-edge wake, have influences on fin's surface pressure; among these factors, the bow shocks are stronger than separated shocks, furthermore it can generate larger high pressure region. Then we find out the aerodynamic characteristics of several typical control layouts at a supersonic speed, Ma=2.5, furthermore, hence nearly 4.8% drag is increase compared with the condition without microflap. As the number of microflaps increasing, the control aerodynamic forces and moments increases almost linearly. With a proper layout of the microflap's location, quick change in the surface pressure distribution can be achieved for rear fins of the projectile, the microflap should be mounted that can increase the high pressure zone, meanwhile, reduce the low pressure zone on the surface of fins, thus modulating the projectile's attitude can be realized.
Research on Pricing of Flexible Two-Dimensional Extended Warranty Considering Preventive Maintenance
Authors: Zhang Xiaolei , Su Chun
Published: August 2019

Facing the uncertainty in transaction of two-dimensional extended warranty, a flexible pricing model is presented considering imperfect preventive maintenance combined with the degradation characteristics of item. The measure of two-dimensional preventive maintenance is carried out based on specified age interval or usage interval, the effect of imperfect preventive maintenance is described by age reduction model. The extended warranty cost is modeled from the perspective of manufacturer and customer, the method of gridding search is employed to optimize the maintenance strategy under different cases. Moreover, customized extended warranty price and warranty services are proposed on the basis of consumer usage rates. The results demonstrate that it is helpful to maximize the benefit of vendor by providing customized warranty strategy, the implementation of preventive maintenance during the whole warranty period can effectively reduce warranty cost for both sides.
Implant-type tissue-engineered cartilage derived from human auricular chondrocyte may maintain cartilaginous property even under osteoinductive condition
Authors: Saka Natsumi , Watanabe Yoshinobu , Abe Satoshi , Yajima Ayako , Kawano Hirotaka
Published: August 2019

Introduction: There is a growing need for chondrocyte implantation for reconstructing cartilage defect. However, ossification of the implanted cartilage is a challenging problem. Implant-type tissue-engineered cartilage from human auricular chondrocytes is a three-dimensional implant type cartilage using PLLA as a scaffold for chondrocytes. Although there is a study which evaluated the ossification of this cartilage in subcutaneous area, there is no study which clarify the possibility of ossification in osteoinductive surroundings. The purpose of this study was to elucidate the possibility of the ossification of implant-type tissue-engineered cartilage using human auricular chondrocyte in an osteoinductive environment. Methods: Human chondrocytes were harvested from ear cartilage. After dispersion by enzyme digestion, they were put into either a poly-L-lactic acid (PLLA) or poly lactic-co-glycolic acid (PLGA) scaffold, with collagen gel. Implant-type tissue-engineered cartilage was interposed between pieces of human iliac bone harvested from the same donor and implanted subcutaneously in nude rats. Scaffold without chondrocytes was used as a control. After 1, 3, and 6 months, ossification and cartilage formation were evaluated by X-ray, hematoxylin-eosin (HE) stain and toluidine blue (TB) stain. Results: There was no ossification of implant-type cartilage using human chondrocytes, even under osteoinductive conditions. HE staining showed that perichondrium formed around the constructs and chondrocytes were observed 6months after the implantation. TB staining showed metachromasia in every sample, with the area of metachromasia increasing over time, suggesting maturation of the cartilage. Conclusions: In conclusion, adjacent iliac bone had no apparent effect on the maturation of cartilage in implant-type tissue-engineered cartilage. Cartilage retention and maturation even in the presence of iliac bone could have been due to a scarcity of mesenchymal stem cells in the bone and surrounding area.
Angst und Depression bei Schilddrüsenerkrankungen
Authors: Quante Arnim
Published: August 2019

Der Zusammenhang zwischen insbesondere Schilddrüsenunterfunktionen und depressiver Symptomatik ist allseits seit Jahrzehnten bekannt. Im Rahmen einer Autoimmunthyreoiditis (AIT) kommt es in der Regel zu einer Unterfunktion der Schilddrüse, die bei Patienten mit Depression häufiger zu finden sind als bei gesunden Kontrollen und umgekehrt. Neben affektiven Erkrankungen sind in den letzten Jahren auch zunehmend andere psychische Erkrankungen mit Autoimmunerkrankungen in Verbindung gebracht worden, wie z. B. Schizophrenien und Angsterkrankungen.
Die „Big Five“ als Erklärungsnarrativ von Behandlungseffekten? – Ergebnisse eines Reviews
Authors: Ernst Jochen
Published: August 2019

Das Fünf-Faktoren-Modell der Persönlichkeitspsychologie (auch „Big Five“) nimmt 5 Hauptdimensionen der menschlichen Persönlichkeit an: Offenheit, Gewissenhaftigkeit, Extraversion, Verträglichkeit und Neurotizismus. Die Forschung der letzten Jahrzehnte belegt eindrücklich den hohen prädiktiven Gehalt dieser Faktoren etwa für die individuelle Leistungsbereitschaft, den beruflichen Erfolg oder auch für gesundheitsbezogene Outcomes.
Wohin mit den (Lehr-)Büchern?
Authors: Mehnert-Theuerkauf Anja
Published: August 2019

Als der japanische Architekt Toyo Ito die 2001 eingeweihte Mediathek in Sendai, Japan, entwarf, stellte er sich ein Gebäude vor, dass Transparenz und Durchlässigkeit zwischen einem Ort des Wissens und des Lernens und dem Leben in der Stadt suggeriert: Ein fließender Raum 1. Das Bauwerk beherbergt eine öffentliche Mediathek, die Bücher für Erwachsene und Kinder, Zeitungen und Zeitschriften, Filme, Dokumentationen, Musik, Hörbücher und Tonaufnahmen, alle Arten von elektronischen Ressourcen sowie Recherche-Datenbanken und öffentliche Internetarbeitsplätze enthält. Auf den 7 Etagen gibt es aber noch mehr: Besprechungs- und Tagungsräume, einen „Open Square“-Mehrzweck-Veranstaltungsort, öffentliche Galerieräume und Ausstellungsflächen, Ateliers, ein Kino, ein Café und umfassende Informationsangebote.
Hitze und Kälte in der Traditionellen Chinesischen Medizin: Zwei Fallbeispiele
Authors: Stockenreiter Josef
Published: August 2019

Die Begriffe Hitze und Kälte in der Traditionellen Chinesischen Medizin (TCM) beziehen sich auf die Relation von Yin und Yang im Körper. Ihre klinischen Manifestationen hängen von der Kombination Fülle oder Leere ab. Die folgenden 2 Fallbeispiele beschreiben mögliche Behandlungsoptionen.
Effects of Two High-intensity Interval Training Concepts in Recreational Runners
Authors: Faelli Emanuela , Ferrando Vittoria , Bisio Ambra , Ferrando Mara , Torre Antonio La , Panasci Marco , Ruggeri Piero
Published: August 2019

This study investigated the effects induced by 8 weeks of two high-intensity interval training (HIIT) protocols, 10–20–30 and 30–30 concepts, characterized by significantly different training volume and intensity, on physiological parameters, running performance, body composition and psychophysiological stress of recreational divided into two groups: the 10–20–30 group performed two 10–20–30 sessions/wk and one continuous training (CT)/wk, whilst the 30–30 group performed two 30–30 sessions/wk and one CT session/wk. VO2max, 1 km time, maximal aerobic speed (MAS), and body composition were evaluated before and after intervention. Internal load was measured through rating of perceived exertion (RPE). Both groups significantly improved running performance (1 km time: p=0.04; MAS: p=0.000001), aerobic fitness (VO2max: p=0.000002) and body composition (lean mass (kg) p=0.0001; fat mass (%) p=0.00005). RPE resulted significantly lower in the 10–20–30 group than in 30–30 group (10–20–30: 13.36±0.28; 30–30:15.55±0.21; p=0.0002). Thus, the 10–20–30 group improved physiological parameters, performance and body composition, similar to 30–30 with significantly lower RPE values. These results suggest that in recreational runners the 10–20–30 training is effective in improving aerobic fitness and performance, with a lower subjective perception of effort, thus enhancing individual compliance and adherence to the prescribed training program.
Sequential multistenting protocol in biliary stenosis after liver transplantation: a prospective analysis
Authors: Tarantino Ilaria , Amata Michele , Cicchese Noemi , Ligresti Dario , Barresi Luca , Granata Antonino , Cipolletta Fabio , Tuzzolino Fabio , Traina Mario
Published: August 2019

Background Biliary complications are a serious source of morbidity after orthotopic and living-related liver transplantation. Endoscopic retrograde cholangiography (ERC) is the gold standard for patients with duct-to-duct anastomosis because it allows a direct approach for interventional procedures. A retrospective study showed results of a sequential multistenting protocol, without stent removal/exchange, with promising results. We conducted a prospective analysis to assess the clinical success, recurrence rate, and adverse event rate related to this protocol.

Methods From May 2012 to April 2018, all consecutive patients with a diagnosis of anastomotic stenosis following liver transplantation were enrolled in the study, and were followed for a period of at least 6 months after the last ERC. During the first ERC, a maximum number of plastic stents (10 Fr) were placed. In subsequent ERCs, scheduled every 3 months up to a maximum of 1 year, additional stents were inserted, as many as possible, without removing the previously placed stents.

Results From May 2012 to May 2018, 87 patients were included in the study and treated with a sequential multistenting protocol. The mean number of stents placed was 3.7 (SD 1.0). Clinical success (stricture resolution and normalization of cholestasis) was achieved in 86 patients (98.9 %). Seven patients (8.0 %) developed complications. Recurrence was recorded in seven patients (8.0 %) after a mean of 992.7 days (SD 622.1).

Conclusions This study represents the first prospective demonstration of the efficacy and safety of a sequential multistenting protocol. A key limitation of the study is the lack of a comparative group treated according to the traditional stent exchange approach.
Treatment of Central Nervous System Manifestations of HIV in the Current Era
Authors: Handoko Ryan , Spudich Serena
Published: August 2019

Treatment of neurological, neurocognitive, and neuropsychiatric impairment in the setting of human immunodeficiency virus (HIV) infection remains a complex problem, given several possible mechanisms of pathogenesis. The etiology must be determined based on clinical judgment and objective evidence, including cerebrospinal fluid (CSF) data from lumbar puncture and neuroimaging information from magnetic resonance imaging, when available and indicated. Other neuroinfectious etiologies must be ruled out, including central nervous system (CNS) opportunistic infections. HIV replication in the CNS (including CSF escape) should be evaluated for and excluded. If CSF HIV is detected, we recommend a treatment switch to antiretrovirals (ARVs) targeted to address any CSF HIV resistance mutations identified, or empiric treatment intensification using ARVs with high CNS penetration. If CSF HIV is not detected, treatment intensification with CCR5 inhibitors may be considered as an adjunct to reduce neuroinflammation. Finally, the current ARV regimen must be examined for possible neurotoxicity. Efavirenz has been well-recognized for its neuropsychiatric adverse effects and potential for causing sleep disturbances. Similar concerns have recently been raised with integrase inhibitors, especially dolutegravir and raltegravir, although further studies are needed to determine the risks for clinically relevant neuropsychiatric side effects from these medications, given their overall high potency and proven success in treating systemic HIV.
Bacterial Infections of the Central Nervous System
Authors: LaPenna Paul A. , Roos Karen L.
Published: August 2019

Acute bacterial meningitis and spinal epidural abscess are neurological emergencies. Acute bacterial meningitis may present with symptoms as nonspecific as headache and fever, but rapid progression to an altered level of consciousness is not unusual. Spinal epidural abscess manifests initially as back pain, followed by radicular pain, then weakness, and finally paraplegia. Brain abscess may initially present only with headache, or as a new-onset seizure or with a focal neurological deficit. Bacterial infections of the central nervous system require emergent diagnosis and management. In this article, the pathogenesis, etiological organisms, diagnostic studies, differential diagnosis and management of acute bacterial meningitis, spinal epidural abscess, and brain abscess are discussed.
Using Context-Sensitive Text Mining to Identify miRNAs in Different Stages of Atherosclerosis
Authors: Joppich Markus , Weber Christian , Zimmer Ralf
Published: August 2019

790 human and mouse micro-RNAs (miRNAs) are involved in diseases. More than 26,428 miRNA–gene interactions are annotated in humans and mice. Most of these interactions are posttranscriptional regulations: miRNAs bind to the messenger RNAs (mRNAs) of genes and induce their degradation, thereby reducing the gene expression of target genes. For atherosclerosis, 667 miRNA–gene interactions for 124 miRNAs and 343 genes have been identified and described in numerous publications. Some interactions were observed through high-throughput experiments, others were predicted using bioinformatic methods, and some were determined by targeted experiments. Several reviews collect knowledge on miRNA–gene interactions in (specific aspects of) atherosclerosis.

Here, we use our bioinformatics resource (atheMir) to give an overview of miRNA–gene interactions in the context of atherosclerosis. The interactions are based on public databases and context-based text mining of 28 million PubMed abstracts. The miRNA–gene interactions are obtained from more than 10,000 publications, of which more than 1,000 are in a cardiovascular disease context (266 in atherosclerosis). We discuss interesting miRNA–gene interactions in atherosclerosis, grouped by specific processes in different cell types and six phases of atherosclerotic progression. All evidence is referenced and easily accessible: Relevant interactions are provided by atheMir as supplementary tables for further evaluation and, for example, for the subsequent data analysis of high-throughput measurements as well as for the generation and validation of hypotheses. The atheMir approach has several advantages: (1) the evidence is easily accessible, (2) regulatory interactions are uniformly available for subsequent high-throughput data analysis, and (3) the resource can incrementally be updated with new findings.
The Basics of Integra Dermal Regeneration Template and its Expanding Clinical Applications
Authors: Chang Daniel K. , Louis Matthew R. , Gimenez Alejandro , Reece Edward M.
Published: August 2019

First developed for coverage of burn wounds, Integra (Integra LifeSciences) is a synthetic acellular dermal regeneration template that provides a base for revascularization and neodermal formation. The use of Integra has slowly grown and has now become an important consideration along the reconstructive ladder. This article reviews the basic science of Integra and provides an overview of the many expanding applications based on anatomic location.
Involvement of Platelets in Cancers
Authors: Mege Diane , Aubert Mathilde , Lacroix Romaric , Dignat-George Françoise , Panicot-Dubois Laurence , Dubois Christophe
Published: August 2019

Cancer-related venous thromboembolism (VTE) is frequent and constitutes the second leading cause of death in patients with cancer. High platelet count is one of independent predictive factors of cancer-associated VTE. Besides the implication of platelets in cancer-associated VTE, recent clinical and experimental evidences support that platelets play several roles in the progression of malignancies and inversely, cancer can also influence platelet count and activity. The objective of this report is to review the current literature regarding the role of platelets in cancer through experimental results and population-based studies. Platelets are implicated in cancer progression and metastasis through proangiogenic factors (growth factors and signaling pathways), antiangiogenic factors (angiostatin, endostatin, thrombospondin-1), and matrix metalloproteinases. In addition, platelets are involved in cancer-associated thrombosis and thus tumor cell-induced platelet activation, through anionic phospholipids on their surface, released soluble factors, such as P-selectin, CD40 ligand, platelet factor 4, thrombospondin-1 or beta-thromboglobulin, tumor cell procoagulant proteins (tissue factor, urokinase-type plasminogen activator, plasminogen activator inhibitor type 1), and microparticles. Due to these different mechanisms, platelets may represent a potential therapeutic target. The main current treatments against platelets are: (1) acetylsalicylic acid (aspirin) and nonsteroidal anti-inflammatory drugs, nonselective cyclo-oxygenase (COX)-1 and COX-2 inhibitors, which are associated with decreased cancer incidence and better overall survival and (2) irreversible inhibitor of P2Y12 subtype which decreases cancer incidence. Platelets are key players in tumor growth, metastasis, and cancer-associated thrombosis. This multifaceted role identifies them as a relevant therapeutic target for prevention of cancer occurrence and treatment of cancer.
Pathogenesis and Management of Thrombotic Disease in Myeloproliferative Neoplasms
Authors: Arachchillage Deepa RJ , Laffan Mike
Published: August 2019

Chronic myeloproliferative neoplasms (MPN) are characterized by clonal expansion of an abnormal hematopoietic stem/progenitor cell and include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Venous thrombosis, often at unusual sites, including splanchnic vein thrombosis and arterial thrombosis, as well as a hemorrhagic tendency and a propensity to transform into myelofibrosis or acute leukemia are common complications in patients with MPNs. The pathogenesis of thrombosis in MPN patients is complex and multifactorial. Disease related factors, such as an increase in blood cell counts (i.e., leukocytosis, erythrocytosis, and thrombocytosis), and more importantly presence of JAK2 mutation can interact with non-disease patient related factors such as age, previous history of thrombotic events, obesity, hypertension, hyperlipidemia, and presence of thrombophilic defects. The overall rate of recurrent thrombosis after venous thromboembolism (VTE) is 6.0 to 6.5 per 100 patient-years in patients with MPN compared to 2.7 to 3.7 per 100 patient-years in patients without MPN, and antithrombotic therapy with vitamin K antagonists (VKAs) is associated with a clear benefit, reducing the incidence of recurrence by 48 to 69%. Life-long oral anticoagulation with VKAs is the cornerstone of the antithrombotic treatment for splanchnic vein thrombosis (SVT). Patients with MPN-related cerebral venous thrombosis (CVT) should also be treated with long-term anticoagulation with VKAs. The role of direct acting oral anticoagulants in patients with thrombosis and MPN is not established and the use of these anticoagulants should be considered on an individual basis according to the risk of recurrent of VTE and bleeding.