bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from Biomarker Analysis of Neoadjuvant Doxorubicin/Cyclophosphamide Followed by Ixabepilone or Paclitaxel in Early-Stage Breast Cancer
Authors: Horak Christine E. , Pusztai Lajos , Xing Guan , Trifan Ovidiu C. , Saura Cristina , Tseng Ling-Ming , Chan Stephen , Welcher Rosanne , Liu David
Published: April 2023

PDF file - 50K, Correlation between βIII-tubulin IHC (Saura et al. manuscript in preparation) and mRNA expression data. *Median cut-off used to determine high versus low βIII-tubulin mRNA expression. IHC, immunohistochemistry.
Supplementary Table 1 from A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
Authors: Floris Giuseppe , Wozniak Agnieszka , Sciot Raf , Li Haifu , Friedman Lori , Van Looy Thomas , Wellens Jasmien , Vermaelen Peter , Deroose Christophe M. , Fletcher Jonathan A. , Debiec-Rychter Maria , Schöffski Patrick
Published: April 2023

PDF file - 84K, Xenograft models characterization.
Supplementary Figure Legend, Tables 1 - 6 from BMN 673, a Novel and Highly Potent PARP1/2 Inhibitor for the Treatment of Human Cancers with DNA Repair Deficiency
Authors: Shen Yuqiao , Rehman Farah L. , Feng Ying , Boshuizen Julia , Bajrami Ilirjana , Elliott Richard , Wang Bing , Lord Christopher J. , Post Leonard E. , Ashworth Alan
Published: April 2023

PDF file - 133K, Supplementary Table 1. Inhibition of PARP1 enzymatic activity by chiral isomers of BMN 673. Supplementary Table 2. List of genes that are targeted by the siRNA library. Supplementary Table 3: Drug effect (DE) scores for significant siRNA sensitization genes from siRNA PARPi drug sensitization screens. Supplementary Table 4: siRNA drug sensitization profiles for all PARP inhibitors tested. Supplementary Table 5. Chiral selectivity of anti-tumor activities and PARP inhibition potency. Supplementary Table 6. Metabolic stability of BMN 673 in human, dog and rat liver microsomes.
Supplementary Figure 3 from A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
Authors: Floris Giuseppe , Wozniak Agnieszka , Sciot Raf , Li Haifu , Friedman Lori , Van Looy Thomas , Wellens Jasmien , Vermaelen Peter , Deroose Christophe M. , Fletcher Jonathan A. , Debiec-Rychter Maria , Schöffski Patrick
Published: April 2023

PDF file - 566K, Xenograft tumor volume assessment, combined for all models. Tumor volume is expressed in percentage, as ratio between time point x baseline. Data are presented for all models (A), based on PTEN protein expression (B), and PTEN status by FISH (C). In GIST-PSW GDC-0941 treatment as single agent lasted 19 days (*). The dotted line shows the time of treatment withdrawal.
Supplementary Table 1 from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 35K, Clinical information and body tumor methylation status of prostate cancer patients
Supplementary Figure Legend from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 164K
Supplementary Text 1 from A Molecular Taxonomy for Urothelial Carcinoma
Authors: Sjödahl Gottfrid , Lauss Martin , Lövgren Kristina , Chebil Gunilla , Gudjonsson Sigurdur , Veerla Srinivas , Patschan Oliver , Aine Mattias , Fernö Mårten , Ringnér Markus , Månsson Wiking , Liedberg Fredrik , Lindgren David , Höglund Mattias
Published: April 2023

PDF file - 519K, Preprocessing of expression data, Identification of molecular subtypes in urothelial carcinoma, validation of MS subtypes in independent datasets, sample classification
Supplementary Figure 4 from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 281K, HIC1 expression had a significant effect on reducing osseous destruction of PCa cells
Supplementary Figure 1 from HIC1 Modulates Prostate Cancer Progression by Epigenetic Modification
Authors: Zheng Jianghua , Wang Jinglong , Sun Xueqing , Hao Mingang , Ding Tao , Xiong Dan , Wang Xiumin , Zhu Yu , Xiao Gang , Cheng Guangcun , Zhao Meizhong , Zhang Jian , Wang Jianhua
Published: April 2023

PDF file - 416K, Methylation status of HIC1 promoter in plasma DNA from PCa patients and healthy controls.
Supplementary Figure 7 from Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma
Authors: Levi Jelena , Kothapalli Sri-Rajashekar , Bohndiek Sarah , Yoon Joon-Kee , Dragulescu-Andrasi Anca , Nielsen Carsten , Tisma Aleksandra , Bodapati Sunil , Gowrishankar Gayatri , Yan Xinrui , Chan Carmel , Starcevic Daniela , Gambhir Sanjiv Sam
Published: April 2023

PDF file - 434K, Optical imaging of the probes' clearance
Supplementary Figure 6 from Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma
Authors: Levi Jelena , Kothapalli Sri-Rajashekar , Bohndiek Sarah , Yoon Joon-Kee , Dragulescu-Andrasi Anca , Nielsen Carsten , Tisma Aleksandra , Bodapati Sunil , Gowrishankar Gayatri , Yan Xinrui , Chan Carmel , Starcevic Daniela , Gambhir Sanjiv Sam
Published: April 2023

PDF file - 121K, Photoacoustic signal recorded at 680 and 750 nm
Supplementary Figure 1 from Onartuzumab (MetMAb): Using Nonclinical Pharmacokinetic and Concentration–Effect Data to Support Clinical Development
Authors: Xiang Hong , Bender Brendan C. , Reyes Arthur E. , Merchant Mark , Jumbe Nelson L. ‘Shasha’ , Romero Mally , Davancaze Teresa , Nijem Ihsan , Mai Elaine , Young Judy , Peterson Amy , Damico-Beyer Lisa A.
Published: April 2023

PDF file, 1199K, Tumor growth inhibition.
Supplementary Figure 1 from In Vitro and In Vivo Antitumor Activity of a Novel Alkylating Agent, Melphalan-Flufenamide, against Multiple Myeloma Cells
Authors: Chauhan Dharminder , Ray Arghya , Viktorsson Kristina , Spira Jack , Paba-Prada Claudia , Munshi Nikhil , Richardson Paul , Lewensohn Rolf , Anderson Kenneth C.
Published: April 2023

PDF file - 4200K, Supplementary Figure 1 (A) MM.1R and RPMI-8226 MM cells were treated with mel-flufen {1μM and 3μM, respectively} for 24h; protein lysates were subjected to immunoblotting using indicated antibodies. (B) MM1.R cells were treated with increasing concentrations of mel-flufen for 16h; cells were then stained with DCF-DA (2'-7'-Dichloro-Fluorescein Diacetate) and ROS production was assessed by flow cytometry (mean � SD; P < 0.05, n=3). As a positive control, bortezomib-treated cells were also assessed for ROS generation. (C) MM.1R cells were treated with indicated concentrations of mel-flufen for 16h; cells were then stained with the cationic dye, JC-1 and the disruption of mitochondrial transmembrane potential was assessed using by flow cytometry (mean � SD; P < 0.05, n=3). (D) RPMI-8266, MM.1R and MM.1S cell were treated with mel-flufen (3 μM, 1 μM, and 1 μM, respectively) for 24h and cytosolic extracts were analyzed for cytochrome-c release by ELISA (n = 3, mean � SD; P < 0.05). (E) MM.1S, MM.1R, and RPMI-8226 cells were treated with mel-flufen in the presence or absence of ZVAD-FMK for 24h, and cell viability was measured using MTT assay (n = 3, mean � SD; P < 0.001).
Supplementary Figure 1 from γ-H2AX Foci Formation as a Pharmacodynamic Marker of DNA Damage Produced by DNA Cross-Linking Agents: Results from 2 Phase I Clinical Trials of SJG-136 (SG2000)
Authors: Wu Jenny , Clingen Peter H. , Spanswick Victoria J. , Mellinas-Gomez Maria , Meyer Tim , Puzanov Igor , Jodrell Duncan , Hochhauser Daniel , Hartley John A.
Published: April 2023

PDF file - 105K, Measurement of γ-H2AX foci in lymphocytes (A) and xenograft tumor cells (B) following treatment of mice i.v. with either 0.15 or 0.3 mg/kg SJG-136. Samples were obtained at 2 and 24 hours and processed as described in materials and methods. Data are expressed as the % of cells which contain 0, 0-5, 5-10, 10-15, 15-20 or >20 foci.
Supplementary Figure 8 from Electrocardiographic Studies of Romidepsin Demonstrate Its Safety and Identify a Potential Role for KATP Channel
Authors: Noonan Anne M. , Eisch Robin A. , Liewehr David J. , Sissung Tristan M. , Venzon David J. , Flagg Thomas P. , Haigney Mark C. , Steinberg Seth M. , Figg William D. , Piekarz Richard L. , Bates Susan E.
Published: April 2023

Supplementary Figure 8 - PDF file 299K, Changes in mean heart rate during cycles 2 when patients taking betablockers were excluded
Supplementary Figure 1 from Electrocardiographic Studies of Romidepsin Demonstrate Its Safety and Identify a Potential Role for KATP Channel
Authors: Noonan Anne M. , Eisch Robin A. , Liewehr David J. , Sissung Tristan M. , Venzon David J. , Flagg Thomas P. , Haigney Mark C. , Steinberg Seth M. , Figg William D. , Piekarz Richard L. , Bates Susan E.
Published: April 2023

Supplementary Figure 1 - PDF file 69K, Changes in heart rate observed for patients in the NIH cohort during cycle 1 days 1, 8 and 15
Supplementary Figure 1 from A Single Nucleotide Polymorphism in Inflammatory Gene RNASEL Predicts Outcome after Radiation Therapy for Localized Prostate Cancer
Authors: Schoenfeld Jonathan D. , Margalit Danielle N. , Kasperzyk Julie L. , Shui Irene M. , Rider Jennifer R. , Epstein Mara M. , Meisner Allison , Kenfield Stacey A. , Martin Neil E. , Nguyen Paul L. , Kantoff Philip W. , Giovannucci Edward L. , Stampfer Meir J. , Mucci Lorelei A.
Published: April 2023

PDF file - 49K, Participant Flow Diagram
Supplementary Figure 1 from Targeting the NF-κB and mTOR Pathways with a Quinoxaline Urea Analog That Inhibits IKKβ for Pancreas Cancer Therapy
Authors: Radhakrishnan Prakash , Bryant Vashti C. , Blowers Elizabeth C. , Rajule Rajkumar N. , Gautam Nagsen , Anwar Muhammad M. , Mohr Ashley M. , Grandgenett Paul M. , Bunt Stephanie K. , Arnst Jamie L. , Lele Subodh M. , Alnouti Yazen , Hollingsworth Michael A. , Natarajan Amarnath
Published: April 2023

PDF file - 76K, Dose and time dependent effect of 13-197 on Capan2 cell growth
Supplementary Materials and Methods from Downregulation of FOXO3a Promotes Tumor Metastasis and Is Associated with Metastasis-Free Survival of Patients with Clear Cell Renal Cell Carcinoma
Authors: Ni Dong , Ma Xin , Li Hong-Zhao , Gao Yu , Li Xin-Tao , Zhang Yu , Ai Qing , Zhang Peng , Song Er-Lin , Huang Qing-Bo , Fan Yang , Zhang Xu
Published: April 2023

PDF file - 137KB
Supplementary Figure Legend from An In Vivo Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas
Authors: Murphy Katherine A. , Lechner Melissa G. , Popescu Flavia E. , Bedi Jessica , Decker Stacy A. , Hu Peisheng , Erickson Jami R. , O'Sullivan M. Gerard , Swier Lauryn , Salazar Andres M. , Olin Michael R. , Epstein Alan L. , Ohlfest John R.
Published: April 2023

PDF file, 72K.
Supplementary Figure 6 from An In Vivo Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas
Authors: Murphy Katherine A. , Lechner Melissa G. , Popescu Flavia E. , Bedi Jessica , Decker Stacy A. , Hu Peisheng , Erickson Jami R. , O'Sullivan M. Gerard , Swier Lauryn , Salazar Andres M. , Olin Michael R. , Epstein Alan L. , Ohlfest John R.
Published: April 2023

PDF file, 149K, T cell expansion comparable between vaccine and vaccine/Fc-OX40L groups at early time points.
Supplementary Figure 1 from An In Vivo Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas
Authors: Murphy Katherine A. , Lechner Melissa G. , Popescu Flavia E. , Bedi Jessica , Decker Stacy A. , Hu Peisheng , Erickson Jami R. , O'Sullivan M. Gerard , Swier Lauryn , Salazar Andres M. , Olin Michael R. , Epstein Alan L. , Ohlfest John R.
Published: April 2023

PDF file, 301K, Bioluminescence imaging to track tumor progression over time.
Supplementary Table 2 from TGF-β–Induced Upregulation of malat1 Promotes Bladder Cancer Metastasis by Associating with suz12
Authors: Fan Yu , Shen Bing , Tan Mingyue , Mu Xinyu , Qin Yan , Zhang Fang , Liu Yong
Published: April 2023

PDF file - 46K, Primer Sequence in the study.
Supplementary Figure 2 from TGF-β–Induced Upregulation of malat1 Promotes Bladder Cancer Metastasis by Associating with suz12
Authors: Fan Yu , Shen Bing , Tan Mingyue , Mu Xinyu , Qin Yan , Zhang Fang , Liu Yong
Published: April 2023

PDF file - 123K, Ezh2 regulates E-cadherin expression.
Supplementary Figure 3 from Identification and Analysis of In Vivo VEGF Downstream Markers Link VEGF Pathway Activity with Efficacy of Anti-VEGF Therapies
Authors: Brauer Matthew J. , Zhuang Guanglei , Schmidt Maike , Yao Jenny , Wu Xiumin , Kaminker Joshua S. , Jurinka Stefanie S. , Kolumam Ganesh , Chung Alicia S. , Jubb Adrian , Modrusan Zora , Ozawa Tomoko , James C. David , Phillips Heidi , Haley Benjamin , Tam Rachel N.W. , Clermont Anne C. , Cheng Jason H. , Yang Sherry X. , Swain Sandra M. , Chen Daniel , Scherer Stefan J. , Koeppen Hartmut , Yeh Ru-Fang , Yue Peng , Stephan Jean-Philippe , Hegde Priti , Ferrara Napoleone , Singh Mallika , Bais Carlos
Published: April 2023

PDF file - 63K, Fig S3. Enrichment of VDV markers Tumor-Associated Endothelial Cells.
Supplementary Figure 2 from Identification and Analysis of In Vivo VEGF Downstream Markers Link VEGF Pathway Activity with Efficacy of Anti-VEGF Therapies
Authors: Brauer Matthew J. , Zhuang Guanglei , Schmidt Maike , Yao Jenny , Wu Xiumin , Kaminker Joshua S. , Jurinka Stefanie S. , Kolumam Ganesh , Chung Alicia S. , Jubb Adrian , Modrusan Zora , Ozawa Tomoko , James C. David , Phillips Heidi , Haley Benjamin , Tam Rachel N.W. , Clermont Anne C. , Cheng Jason H. , Yang Sherry X. , Swain Sandra M. , Chen Daniel , Scherer Stefan J. , Koeppen Hartmut , Yeh Ru-Fang , Yue Peng , Stephan Jean-Philippe , Hegde Priti , Ferrara Napoleone , Singh Mallika , Bais Carlos
Published: April 2023

PDF file - 708K, Fig S2A. Histological evidence for the in vivo activity of VEGF pathway inhibitors in MDA-MB-231 tumors. Fig S2B. In vivo VEGF blockade or VEGFR-2 downstream signaling inhibition induces consistent downregulation of proxVDV genes. Fig S2C. The proxVDV gene ESM1 is an in vivo VEGF target specifically expressed in tumor-associated vasculature
Supplementary Table 3 from Identifying and Targeting ROS1 Gene Fusions in Non–Small Cell Lung Cancer
Authors: Davies Kurtis D. , Le Anh T. , Theodoro Mariana F. , Skokan Margaret C. , Aisner Dara L. , Berge Eamon M. , Terracciano Luigi M. , Cappuzzo Federico , Incarbone Matteo , Roncalli Massimo , Alloisio Marco , Santoro Armando , Camidge D. Ross , Varella-Garcia Marileila , Doebele Robert C.
Published: April 2023

PDF file - 36K, Details of FISH and RT-PCR analysis of ROS1 positive patients
Supplementary Figure 1 from Temozolomide Does Not Impair Gene Therapy-Mediated Antitumor Immunity in Syngeneic Brain Tumor Models
Authors: Candolfi Marianela , Yagiz Kader , Wibowo Mia , Ahlzadeh Gabrielle E. , Puntel Mariana , Ghiasi Homayon , Kamran Neha , Paran Christopher , Lowenstein Pedro R. , Castro Maria G.
Published: April 2023

PDF file - 5039K, HMGB1 translocation in vitro in citrine-GL26-Cherry-HMGB1 cells.
Supplementary Methods from Predicting Response to Bevacizumab in Ovarian Cancer: A Panel of Potential Biomarkers Informing Treatment Selection
Authors: Collinson Fiona , Hutchinson Michelle , Craven Rachel A. , Cairns David A. , Zougman Alexandre , Wind Tobias C. , Gahir Narinder , Messenger Michael P. , Jackson Sharon , Thompson Douglas , Adusei Cybil , Ledermann Jonathan A. , Hall Geoffrey , Jayson Gordon C. , Selby Peter J. , Banks Rosamonde E.
Published: April 2023

PDF file - 84K
Supplementary Table 2 from Associations between Single-Nucleotide Polymorphisms in the PI3K–PTEN–AKT–mTOR Pathway and Increased Risk of Brain Metastasis in Patients with Non–Small Cell Lung Cancer
Authors: Li Qianxia , Yang Ju , Yu Qianqian , Wu Huanlei , Liu Bo , Xiong Huihua , Hu Guangyuan , Zhao Jing , Yuan Xianglin , Liao Zhongxing
Published: April 2023

PDF file - 84K, Associations between genotypes and brain metastases, excluding those with BM at initial diagnosis of non-small cell lung cancer (the other 13 selected SNPs).
Supplementary Table 1 from Associations between Single-Nucleotide Polymorphisms in the PI3K–PTEN–AKT–mTOR Pathway and Increased Risk of Brain Metastasis in Patients with Non–Small Cell Lung Cancer
Authors: Li Qianxia , Yang Ju , Yu Qianqian , Wu Huanlei , Liu Bo , Xiong Huihua , Hu Guangyuan , Zhao Jing , Yuan Xianglin , Liao Zhongxing
Published: April 2023

PDF file - 82K, Associations between genotypes and brain metastases (the other 13 selected SNPs).
Supplementary Table 2 from The Prognostic Significance and Therapeutic Potential of Hedgehog Signaling in Intrahepatic Cholangiocellular Carcinoma
Authors: Tang Liang , Tan Ye-Xiong , Jiang Bei-Ge , Pan Yu-Fei , Li Shuang-Xi , Yang Guang-Zhen , Wang Min , Wang Qing , Zhang Jian , Zhou Wei-Ping , Dong Li-Wei , Wang Hong-Yang
Published: April 2023

PDF file - 141K, Univariate and multivariate Cox regression analyses Gli1, Gli2, Shh for DFS or OS of patients in the validation cohort.
Supplementary Figure 1 from The Prognostic Significance and Therapeutic Potential of Hedgehog Signaling in Intrahepatic Cholangiocellular Carcinoma
Authors: Tang Liang , Tan Ye-Xiong , Jiang Bei-Ge , Pan Yu-Fei , Li Shuang-Xi , Yang Guang-Zhen , Wang Min , Wang Qing , Zhang Jian , Zhou Wei-Ping , Dong Li-Wei , Wang Hong-Yang
Published: April 2023

PDF file- 795K, Bcl2 and c-Myc mRNA expression in intrahepatic cholangiocellular carcinoma specimens.
Supplementary Table 1 from Differences in the Transcriptional Response to Fulvestrant and Estrogen Deprivation in ER-Positive Breast Cancer
Authors: Patani Neill , Dunbier Anita K. , Anderson Helen , Ghazoui Zara , Ribas Ricardo , Anderson Elizabeth , Gao Qiong , A'hern Roger , Mackay Alan , Lindemann Justin , Wellings Robert , Walker Jill , Kuter Irene , Martin Lesley-Ann , Dowsett Mitch
Published: April 2023

PDF file - 33KB, Impact of fulvestrant and E-deprivation on selected index proliferation-associated or E-regulated genes.
Supplementary Figure 2 from miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro
Authors: Mulrane Laoighse , Madden Stephen F. , Brennan Donal J. , Gremel Gabriela , McGee Sharon F. , McNally Sara , Martin Finian , Crown John P. , Jirström Karin , Higgins Desmond G. , Gallagher William M. , O'Connor Darran P.
Published: April 2023

PDF file - 438K, EMT and MMP expression in miR187 expressing MCF7 cells
Supplementary Figure 1 from miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro
Authors: Mulrane Laoighse , Madden Stephen F. , Brennan Donal J. , Gremel Gabriela , McGee Sharon F. , McNally Sara , Martin Finian , Crown John P. , Jirström Karin , Higgins Desmond G. , Gallagher William M. , O'Connor Darran P.
Published: April 2023

PDF file - 414K, miR187 ectopic expression in MCF7, effects on growth, quantification of invasion
Supplementary Figure 7 and Supplementary Figure 8 from Antibody-Mediated Delivery of Anti–KRAS-siRNA In Vivo Overcomes Therapy Resistance in Colon Cancer
Authors: Bäumer Sebastian , Bäumer Nicole , Appel Neele , Terheyden Lisa , Fremerey Julia , Schelhaas Sonja , Wardelmann Eva , Buchholz Frank , Berdel Wolfgang E. , Müller-Tidow Carsten
Published: April 2023

Supplementary Figure 7 and Supplementary Figure 8. Figure S7: KRAS knockdown by mAB-KRASe siRNA in vivo Figure S8: Targeting cooperative oncogenes by mAB-esiRNA treatment.
Supplementary Table 4 from A Panel of Three Markers Hyper- and Hypomethylated in Urine Sediments Accurately Predicts Bladder Cancer Recurrence
Authors: Su Sheng-Fang , de Castro Abreu André Luís , Chihara Yoshitomo , Tsai Yvonne , Andreu-Vieyra Claudia , Daneshmand Siamak , Skinner Eila C. , Jones Peter A. , Siegmund Kimberly D. , Liang Gangning
Published: April 2023

PDF file - 67KB, Association between the score from the three-marker signature and the recurrent bladder tumor pathological characteristics of 34 recurrence patients.
Supplementary Table 2 from A Panel of Three Markers Hyper- and Hypomethylated in Urine Sediments Accurately Predicts Bladder Cancer Recurrence
Authors: Su Sheng-Fang , de Castro Abreu André Luís , Chihara Yoshitomo , Tsai Yvonne , Andreu-Vieyra Claudia , Daneshmand Siamak , Skinner Eila C. , Jones Peter A. , Siegmund Kimberly D. , Liang Gangning
Published: April 2023

PDF file - 125KB, Primer sequences used in pyrosequencing.
Supplementary Table 1 from EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors
Authors: Bladt Friedhelm , Faden Bettina , Friese-Hamim Manja , Knuehl Christine , Wilm Claudia , Fittschen Claus , Grädler Ulrich , Meyring Michael , Dorsch Dieter , Jaehrling Frank , Pehl Ulrich , Stieber Frank , Schadt Oliver , Blaukat Andree
Published: April 2023

PDF file - 53K, Characteristics of the antibodies used in the study. The specificity, isotype, clone number, and commercial source of the antibodies used throughout the study are indicated. All antibodies were used according to the manufacturer's instructions.
Supplementary Figure Legend from EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors
Authors: Bladt Friedhelm , Faden Bettina , Friese-Hamim Manja , Knuehl Christine , Wilm Claudia , Fittschen Claus , Grädler Ulrich , Meyring Michael , Dorsch Dieter , Jaehrling Frank , Pehl Ulrich , Stieber Frank , Schadt Oliver , Blaukat Andree
Published: April 2023

PDF file - 92K
Supplementary Figure 8 from EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors
Authors: Bladt Friedhelm , Faden Bettina , Friese-Hamim Manja , Knuehl Christine , Wilm Claudia , Fittschen Claus , Grädler Ulrich , Meyring Michael , Dorsch Dieter , Jaehrling Frank , Pehl Ulrich , Stieber Frank , Schadt Oliver , Blaukat Andree
Published: April 2023

PDF file - 184K, EMD 1214063 and EMD 1204831 display anti-tumor activity in HGF-dependent and HGF-independent xenograft tumor models. Mice bearing subcutaneous tumors derived from the human gastric Hs746T cell line (A and B) or the glioblastoma U87MG cell line (C and D) were administered daily the indicated doses of EMD 1214063 (A and C), EMD 1204831 (B and D), or vehicle for the indicated treatment duration. Each data point represents the mean � SD of the calculated tumor volumes observed in experimental groups including ten mice. Statistical significance was evaluated by one-way ANOVA (Kruskal-Wallis, Dunn's post test). Asterisks indicate statistically significant differences between treated and control experimental groups (P≤0.05).
Supplementary Table 3 from Phase Ib Study of Buparlisib plus Trastuzumab in Patients with HER2-Positive Advanced or Metastatic Breast Cancer That Has Progressed on Trastuzumab-Based Therapy
Authors: Saura Cristina , Bendell Johanna , Jerusalem Guy , Su Shaun , Ru Qinhua , De Buck Stefan , Mills David , Ruquet Sophie , Bosch Ana , Urruticoechea Ander , Beck Joseph T. , Di Tomaso Emmanuelle , Sternberg David W. , Massacesi Cristian , Hirawat Samit , Dirix Luc , Baselga Jose
Published: April 2023

PDF file - 48K, Exposure to buparlisib and trastuzumab (safety set).
Supplementary Figure 4 from EMD 1214063 and EMD 1204831 Constitute a New Class of Potent and Highly Selective c-Met Inhibitors
Authors: Bladt Friedhelm , Faden Bettina , Friese-Hamim Manja , Knuehl Christine , Wilm Claudia , Fittschen Claus , Grädler Ulrich , Meyring Michael , Dorsch Dieter , Jaehrling Frank , Pehl Ulrich , Stieber Frank , Schadt Oliver , Blaukat Andree
Published: April 2023

PDF file - 240K, Dose-dependent inhibition of c-Met auto-phosphorylation in vivo. Panel A: Mice bearing established tumors, derived from s.c. injection of Hs746T gastric cancer cells, received a single dose of 3 mg/kg , 10 mg/kg , 30 mg/kg , and 100 mg/kg EMD 1214063. The pharmacokinetic profile of EMD 1214063 was defined by measuring the compound levels in plasma and tumor tissue. The lower limits of detection for EMD 1214063 were 0.007 �M (4 ng/mL) in the plasma and 0.037 �M (20 ng/mL) in tumor samples. The levels of c-Met auto-phosphorylation (Y1234/Y1235) were assessed by Western blot analysis and used as a pharmacodynamic marker of activity. Each data point represents the mean � SD of the values obtained from four mice per experimental group. A data point was not shown if any of the values within the experimental group was below the detection limit. Panel B: A similar experimental approach to that already described for EMD 1214063 was used to define the pharmacokinetic profile and pharmacodynamic effects of EMD 1204831. In brief, mice bearing established Hs746T subcutaneous tumors received a single dose of 3 mg/kg, 10 mg/kg, 30 mg/kg, or 100 mg/kg EMD 1204831. In the pharmacokinetic studies, the lower limits of detection for EMD 1204831 were 0.014 �M (8 ng/mL) in the plasma and tumor samples. The pharmacodynamic effects were determined by Western blot analyses of c-Met auto-phosphorylation (Y1234/Y1235). Each data point represents the mean � SD of the values obtained from four mice per experimental group. A data point was not shown if any of the values within the experimental group was below the detection limit.
Supplementary Table 1 from microRNAome Expression in Chronic Lymphocytic Leukemia: Comparison with Normal B-cell Subsets and Correlations with Prognostic and Clinical Parameters
Authors: Negrini Massimo , Cutrona Giovanna , Bassi Cristian , Fabris Sonia , Zagatti Barbara , Colombo Monica , Ferracin Manuela , D'Abundo Lucilla , Saccenti Elena , Matis Serena , Lionetti Marta , Agnelli Luca , Gentile Massimo , Recchia Anna Grazia , Bossio Sabrina , Reverberi Daniele , Rigolin Gianmatteo , Calin George A. , Sabbioni Silvia , Russo Giandomenico , Tassone Pierfrancesco , Morabito Fortunato , Ferrarini Manlio , Neri Antonino
Published: April 2023

XLSX file - 33K, Features of CLL samples.
Supplementary Figure 3 from Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer
Authors: Liu Hanqing , Xiao Fang , Serebriiskii Ilya G. , O'Brien Shane W. , Maglaty Marisa A. , Astsaturov Igor , Litwin Samuel , Martin Lainie P. , Proia David A. , Golemis Erica A. , Connolly Denise C.
Published: April 2023

PDF file - 102KB, Synergistic reduction of cell viability in the cancer cell lines A1847 (A) and OVCAR-5 treated with ganetespib (GAN) in combination with cisplatin (CIS) or Paclitaxel (PAC).
Supplementary Figure 2 from Phase II Trial of MEK Inhibitor Selumetinib (AZD6244, ARRY-142886) in Patients with BRAFV600E/K-Mutated Melanoma
Authors: Catalanotti Federica , Solit David B. , Pulitzer Melissa P. , Berger Michael F. , Scott Sasinya N. , Iyriboz Tunc , Lacouture Mario E. , Panageas Katherine S. , Wolchok Jedd D. , Carvajal Richard D. , Schwartz Gary K. , Rosen Neal , Chapman Paul B.
Published: April 2023

PDF file - 5171K, Schematic representation of gain or deletions across the set of genes on each chromosome in a tumor with MITF amplification. Each dot corresponds to an exon of a specific gene. Every gene expressed higher than 1.5 is considered amplified, while every gene expressed lower than 0.5 is considered deleted. Exons corresponding to MITF are circled in red.
Supplementary Figure 1A from Phase II Trial of MEK Inhibitor Selumetinib (AZD6244, ARRY-142886) in Patients with BRAFV600E/K-Mutated Melanoma
Authors: Catalanotti Federica , Solit David B. , Pulitzer Melissa P. , Berger Michael F. , Scott Sasinya N. , Iyriboz Tunc , Lacouture Mario E. , Panageas Katherine S. , Wolchok Jedd D. , Carvajal Richard D. , Schwartz Gary K. , Rosen Neal , Chapman Paul B.
Published: April 2023

PDF file - 2798K, Immunohistochemical (IHC) staining of high pAKT tumors
Supplementary Table 2 from Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A–Specific T Cells
Authors: Weide Benjamin , Martens Alexander , Zelba Henning , Stutz Christina , Derhovanessian Evelyna , Di Giacomo Anna Maria , Maio Michele , Sucker Antje , Schilling Bastian , Schadendorf Dirk , Büttner Petra , Garbe Claus , Pawelec Graham
Published: April 2023

PDF file - 81K, Frequencies of MDSCs (n=133) and Tregs (n=123) according to type and time-point of prior systemic treatments (combined cohorts).
Supplementary Figure Legend from Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A–Specific T Cells
Authors: Weide Benjamin , Martens Alexander , Zelba Henning , Stutz Christina , Derhovanessian Evelyna , Di Giacomo Anna Maria , Maio Michele , Sucker Antje , Schilling Bastian , Schadendorf Dirk , Büttner Petra , Garbe Claus , Pawelec Graham
Published: April 2023

PDF file - 54K
Supplementary Tables 1 - 2 from Hedgehog–GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer
Authors: Huang Lingling , Walter Vonn , Hayes D. Neil , Onaitis Mark
Published: April 2023

PDF file - 101K, Supplementary Table 1. Results of hypothesis tests used to compare expression values of Hedgehog signaling pathway genes in the expression subtypes of lung squamous cell carcinoma. Supplementary Table 2. Spearman correlation coefficients between GLI2/ GLI1 and the classical subtype markers.
Supplementary Table 2 from CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27− Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer
Authors: Nielsen Julie S. , Sahota Rob A. , Milne Katy , Kost Sara E. , Nesslinger Nancy J. , Watson Peter H. , Nelson Brad H.
Published: April 2023

PDF file, 70KB, Antibodies used for flow cytometry.
Supplementary Table 18 from Nonequivalent Gene Expression and Copy Number Alterations in High-Grade Serous Ovarian Cancers with BRCA1 and BRCA2 Mutations
Authors: George Joshy , Alsop Kathryn , Etemadmoghadam Dariush , Hondow Heather , Mikeska Thomas , Dobrovic Alexander , deFazio Anna , Smyth Gordon K. , Levine Douglas A. , Mitchell Gillian , Bowtell David D.
Published: April 2023

PDF file - 24K
Supplementary Methods, Figure Legends, Figures 1 - 6 from Genetic Modification of T Cells Redirected toward CS1 Enhances Eradication of Myeloma Cells
Authors: Chu Jianhong , He Shun , Deng Youcai , Zhang Jianying , Peng Yong , Hughes Tiffany , Yi Ling , Kwon Chang-Hyuk , Wang Qi-En , Devine Steven M. , He Xiaoming , Bai Xue-Feng , Hofmeister Craig C. , Yu Jianhua
Published: April 2023

PDF file - 1721KB, Detailed methods for cell culture, retroviral transfection, generation of RPMI-8226 cells expressing CS1. Figure S1, killing of 293T cells expressing CS1. Figure S2, activation of T cell subsets. Figure S3, IM-9 in vivo experiment. Figure S4, interaction of normal cells and CAR T cells. Figure S5, activation induced cell death. Figure S6, CAR T cells survival and proliferation.
Supplementary Figure S2 from Ligand-Dependent Activation of EGFR in Follicular Dendritic Cells Sarcoma is Sustained by Local Production of Cognate Ligands
Authors: Vermi William , Giurisato Emanuele , Lonardi Silvia , Balzarini Piera , Rossi Elisa , Medicina Daniela , Bosisio Daniela , Sozzani Silvano , Pellegrini Wilma , Doglioni Claudio , Marchetti Antonio , Rossi Giulio , Pileri Stefano , Facchetti Fabio
Published: April 2023

Dose-dependent FDC-S response to EGF.
Supplementary Table 3 from Next-Generation Sequencing of Translocation Renal Cell Carcinoma Reveals Novel RNA Splicing Partners and Frequent Mutations of Chromatin-Remodeling Genes
Authors: Malouf Gabriel G. , Su Xiaoping , Yao Hui , Gao Jianjun , Xiong Liangwen , He Qiuming , Compérat Eva , Couturier Jérôme , Molinié Vincent , Escudier Bernard , Camparo Philippe , Doss Denaha J. , Thompson Erika J. , Khayat David , Wood Christopher G. , Yu Willie , Teh Bin T. , Weinstein John , Tannir Nizar M.
Published: April 2023

XLSX file - 185K, List of fusion transcripts identified in TCGA cohort, including the number of reads identified spanning the fusion junction.
Supplementary Methods, Tables 1 - 2, Figures 1 - 2 from Validation of a Proliferation-Based Expression Signature as Prognostic Marker in Early Stage Lung Adenocarcinoma
Authors: Wistuba Ignacio I. , Behrens Carmen , Lombardi Francesca , Wagner Susanne , Fujimoto Junya , Raso M. Gabriela , Spaggiari Lorenzo , Galetta Domenico , Riley Robyn , Hughes Elisha , Reid Julia , Sangale Zaina , Swisher Steven G. , Kalhor Neda , Moran Cesar A. , Gutin Alexander , Lanchbury Jerry S. , Barberis Massimo , Kim Edward S.
Published: April 2023

PDF file - 212K, Final list of 31 cell cycle genes in the CCP score and their correlation with the CCP mean in the MDACC-IEO cohort. Supplementary Table 2. Set of 15 housekeeper genes in the CCP score and the correlation of their Ct mean with the housekeeper gene mean in the MDACC-IEO cohort. Supplementary FigureS1. Patient sets and exclusion criteria for the microarray cohorts (A) and the FFPE cohort (B). Supplementary FigureS2. Association between CCP score and lung cancer death in stage I patients: MDACC/IEO combined (A), MDACC subset (B) and IEO subset (C). Each patient set was divided by the median CCP score into two equally sized groups. The patient group with lower CCP scores defines a subpopulation with improved survival.
Supplementary Table 1 from Next-Generation Sequencing of Translocation Renal Cell Carcinoma Reveals Novel RNA Splicing Partners and Frequent Mutations of Chromatin-Remodeling Genes
Authors: Malouf Gabriel G. , Su Xiaoping , Yao Hui , Gao Jianjun , Xiong Liangwen , He Qiuming , Compérat Eva , Couturier Jérôme , Molinié Vincent , Escudier Bernard , Camparo Philippe , Doss Denaha J. , Thompson Erika J. , Khayat David , Wood Christopher G. , Yu Willie , Teh Bin T. , Weinstein John , Tannir Nizar M.
Published: April 2023

XLSX file - 20K, Clinicopathological features of MITF/TFE TRCC samples selected in our cohort for RNA and exome sequencing.
Supplementary Methods from Next-Generation Sequencing of Translocation Renal Cell Carcinoma Reveals Novel RNA Splicing Partners and Frequent Mutations of Chromatin-Remodeling Genes
Authors: Malouf Gabriel G. , Su Xiaoping , Yao Hui , Gao Jianjun , Xiong Liangwen , He Qiuming , Compérat Eva , Couturier Jérôme , Molinié Vincent , Escudier Bernard , Camparo Philippe , Doss Denaha J. , Thompson Erika J. , Khayat David , Wood Christopher G. , Yu Willie , Teh Bin T. , Weinstein John , Tannir Nizar M.
Published: April 2023

PDF file - 79K, Material and Methods describing the TCGA dataset with the RNAseq and exome-sequencing analysis.
Supplementary table S1 from Japonicone A Suppresses Growth of Burkitt Lymphoma Cells through Its Effect on NF-κB
Authors: Li Xiaoguang , Yang Xinying , Liu Yanling , Gong Nuoxi , Yao Wenbo , Chen Peizhan , Qin Jiangjiang , Jin Huizi , Li Jingquan , Chu Ruiai , Shan Lei , Zhang Ruiwen , Zhang Weidong , Wang Hui
Published: April 2023

The cytotoxicity of JA on multiple tumor cells and normal cells (IC50).
Supplementary methods from Japonicone A Suppresses Growth of Burkitt Lymphoma Cells through Its Effect on NF-κB
Authors: Li Xiaoguang , Yang Xinying , Liu Yanling , Gong Nuoxi , Yao Wenbo , Chen Peizhan , Qin Jiangjiang , Jin Huizi , Li Jingquan , Chu Ruiai , Shan Lei , Zhang Ruiwen , Zhang Weidong , Wang Hui
Published: April 2023

Analysis of mitochondrial membrane potential and Lentivirus-encoded shRNA knockdown and NF-κB reporter assay
Supplementary Table from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB
Authors: Gopalakrishnan Ramakrishnan , Matta Hittu , Chaudhary Preet M.
Published: April 2023

PDF file, 77K, The list of qRT-PCR primer sequences used in this study were given in this file.
Supplementary Table 2 from Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib)
Authors: Matas-Céspedes Alba , Rodriguez Vanina , Kalko Susana G. , Vidal-Crespo Anna , Rosich Laia , Casserras Teresa , Balsas Patricia , Villamor Neus , Giné Eva , Campo Elías , Roué Gaël , López-Guillermo Armando , Colomer Dolors , Pérez-Galán Patricia
Published: April 2023

PDF file - 287K, Complete results of Rank products and DAVID analysis.
Supplementary Table 1 from Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib)
Authors: Matas-Céspedes Alba , Rodriguez Vanina , Kalko Susana G. , Vidal-Crespo Anna , Rosich Laia , Casserras Teresa , Balsas Patricia , Villamor Neus , Giné Eva , Campo Elías , Roué Gaël , López-Guillermo Armando , Colomer Dolors , Pérez-Galán Patricia
Published: April 2023

PDF file - 41K, FL patient characteristics.
Supplementary Figure 6 from Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma
Authors: Khalili Jahan S. , Liu Shujuan , Rodríguez-Cruz Tania G. , Whittington Mayra , Wardell Seth , Liu Chengwen , Zhang Minying , Cooper Zachary A. , Frederick Dennie T. , Li Yufeng , Zhang Min , Joseph Richard W. , Bernatchez Chantale , Ekmekcioglu Suhendan , Grimm Elizabeth , Radvanyi Laszlo G. , Davis Richard E. , Davies Michael A. , Wargo Jennifer A. , Hwu Patrick , Lizée Gregory
Published: April 2023

PDF file, 99K, Four separate TAF lines were derived from human melanoma tumor biopsies and exposed overnight to recombinant human IL-1α (1 ng/ml) or IFN-γ (500 U/ml). TAFs were then stained using antibodies specific for PD-L1 and PD-L2, and analyzed for surface expression by flow cytometry.
Supplementary Figure Legends from Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib)
Authors: Matas-Céspedes Alba , Rodriguez Vanina , Kalko Susana G. , Vidal-Crespo Anna , Rosich Laia , Casserras Teresa , Balsas Patricia , Villamor Neus , Giné Eva , Campo Elías , Roué Gaël , López-Guillermo Armando , Colomer Dolors , Pérez-Galán Patricia
Published: April 2023

PDF file - 69K
Supplementary Figure 3 from Disruption of Follicular Dendritic Cells–Follicular Lymphoma Cross-talk by the Pan-PI3K Inhibitor BKM120 (Buparlisib)
Authors: Matas-Céspedes Alba , Rodriguez Vanina , Kalko Susana G. , Vidal-Crespo Anna , Rosich Laia , Casserras Teresa , Balsas Patricia , Villamor Neus , Giné Eva , Campo Elías , Roué Gaël , López-Guillermo Armando , Colomer Dolors , Pérez-Galán Patricia
Published: April 2023

PDF file - 92K, BKM120 inhibits constitutive and HK-induced PI3K/AKT activation.
Supplemental Table 4 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2
Authors: Cardnell Robert J.G. , Behrens Carmen , Diao Lixia , Fan YouHong , Tang Ximing , Tong Pan , Minna John D. , Mills Gordon B. , Heymach John V. , Wistuba Ignacio I. , Wang Jing , Byers Lauren A.
Published: April 2023

Supplemental Table 4. Targets of drugs identified as more effective in TTF1-low cell lines.
Data Supplement from Large-Scale Characterization of DNA Methylation Changes in Human Gastric Carcinomas with and without Metastasis
Authors: Liu Zhaojun , Zhang Jun , Gao Yanhong , Pei Lirong , Zhou Jing , Gu Liankun , Zhang Lianhai , Zhu Budong , Hattori Naoko , Ji Jiafu , Yuasa Yasuhito , Kim Wooho , Ushijima Toshikazu , Shi Huidong , Deng Dajun
Published: April 2023

Supplementary Figure S3. DHPLC chromatograms and bisulfite-sequencing of 12 GC-related gene methylation changes.
Supplemental Figure 3 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2
Authors: Cardnell Robert J.G. , Behrens Carmen , Diao Lixia , Fan YouHong , Tang Ximing , Tong Pan , Minna John D. , Mills Gordon B. , Heymach John V. , Wistuba Ignacio I. , Wang Jing , Byers Lauren A.
Published: April 2023

Supplemental Figure 3. Cell line drug sensitivity, comparison of IC50 values identifies drugs differently active in TTF1 high and low cell lines.
Data Supplement from Large-Scale Characterization of DNA Methylation Changes in Human Gastric Carcinomas with and without Metastasis
Authors: Liu Zhaojun , Zhang Jun , Gao Yanhong , Pei Lirong , Zhou Jing , Gu Liankun , Zhang Lianhai , Zhu Budong , Hattori Naoko , Ji Jiafu , Yuasa Yasuhito , Kim Wooho , Ushijima Toshikazu , Shi Huidong , Deng Dajun
Published: April 2023

Supplementary Figure S2. Volcano-plots showing female/male ratio of the average CCCGGG-methylation signal of each probe for sex chromosomes X (A), Y (B), and autosomes (C) in the SM samples; Distribution of the proportion of hypermethylated and hypomethylated probes relative to the distance to the transcription start sites in the GC methylome (D) and the G+C content (E) in the EpiExplore analysis.
Supplementary Table 2 from Secreted Protein Acidic and Rich in Cysteines-like 1 Suppresses Aggressiveness and Predicts Better Survival in Colorectal Cancers
Authors: Hu Hanguang , Zhang Hang , Ge Weiting , Liu Xiyong , Loera Sofia , Chu Peiguo , Chen Huarong , Peng Jiaping , Zhou Lun , Yu Shujing , Yuan Ying , Zhang Suzhan , Lai Lily , Yen Yun , Zheng Shu
Published: April 2023

PDF file, 49K, The quality of CRC database in COH set and ZJU set.
Supplementary Table S1 from A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non–Small Cell Lung Cancer
Authors: Owonikoko Taofeek K. , Ramalingam Suresh S. , Miller Daniel L. , Force Seth D. , Sica Gabriel L. , Mendel Jennifer , Chen Zhengjia , Rogatko Andre , Tighiouart Mourad , Harvey R. Donald , Kim Sungjin , Saba Nabil F. , Pickens Allan , Behera Madhusmita , Fu Robert W. , Rossi Michael R. , Auffermann William F. , Torres William E. , Bechara Rabih , Deng Xingming , Sun Shi-Yong , Fu Haian , Gal Anthony A. , Khuri Fadlo R.
Published: April 2023

Supplementary Table S1. Differentially expressed genes
Supplementary Figures from A Translational, Pharmacodynamic, and Pharmacokinetic Phase IB Clinical Study of Everolimus in Resectable Non–Small Cell Lung Cancer
Authors: Owonikoko Taofeek K. , Ramalingam Suresh S. , Miller Daniel L. , Force Seth D. , Sica Gabriel L. , Mendel Jennifer , Chen Zhengjia , Rogatko Andre , Tighiouart Mourad , Harvey R. Donald , Kim Sungjin , Saba Nabil F. , Pickens Allan , Behera Madhusmita , Fu Robert W. , Rossi Michael R. , Auffermann William F. , Torres William E. , Bechara Rabih , Deng Xingming , Sun Shi-Yong , Fu Haian , Gal Anthony A. , Khuri Fadlo R.
Published: April 2023

Supplementary Figures. Supplemental Figure S1: Representative sections showing changes in expression between baseline biopsy and post-treatment surgical specimens. Supplemental Figure S2: Correlogram showing the correlation between changes in protein expression immunoscore, metabolic activity on PET and tumor size by CT scan.
Supplementary Table 1 from β-1,4-Galactosyltransferase III Enhances Invasive Phenotypes Via β1-Integrin and Predicts Poor Prognosis in Neuroblastoma
Authors: Chang Hsiu-Hao , Chen Chia-Hua , Chou Chih-Hsing , Liao Yung-Feng , Huang Miao-Juei , Chen Ya-Hsin , Wang Wei-Jen , Huang John , Hung Ji-Shiang , Ho Wan-Ling , Jeng Yung-Ming , Che Mei-Ieng , Lee Hsinyu , Lu Meng-Yao , Yang Yung-Li , Jou Shiann-Tarng , Lin Dong-Tsamn , Lin Kai-Hsin , Hsu Wen-Ming , Huang Min-Chuan
Published: April 2023

PDF file - 40K, Genomic status of NB cell lines
Supplementary Table 3 from To “Grow” or “Go”: TMEM16A Expression as a Switch between Tumor Growth and Metastasis in SCCHN
Authors: Shiwarski Daniel J. , Shao Chunbo , Bill Anke , Kim Jean , Xiao Dong , Bertrand Carol A. , Seethala Raja S. , Sano Daisuke , Myers Jeffery N. , Ha Patrick , Grandis Jennifer , Gaither L. Alex , Puthenveedu Manojkumar A. , Duvvuri Umamaheswar
Published: April 2023

PDF file - 196K, Table summarizing the antibodies used for immunoblotting and IHC.
Supplementary Figure 4 from β-1,4-Galactosyltransferase III Enhances Invasive Phenotypes Via β1-Integrin and Predicts Poor Prognosis in Neuroblastoma
Authors: Chang Hsiu-Hao , Chen Chia-Hua , Chou Chih-Hsing , Liao Yung-Feng , Huang Miao-Juei , Chen Ya-Hsin , Wang Wei-Jen , Huang John , Hung Ji-Shiang , Ho Wan-Ling , Jeng Yung-Ming , Che Mei-Ieng , Lee Hsinyu , Lu Meng-Yao , Yang Yung-Li , Jou Shiann-Tarng , Lin Dong-Tsamn , Lin Kai-Hsin , Hsu Wen-Ming , Huang Min-Chuan
Published: April 2023

PDF file - 1453K, Xenografts from nude mice subcutaneously injected SK-N-DZ/shCtrl and SK-N-DZ/shB4GALT3 cells
Supplementary Tables S1-3 and Figures S1-S5 from Role of NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex 4-Like 2 in Clear Cell Renal Cell Carcinoma
Authors: Minton Denise R. , Fu Leiping , Mongan Nigel P. , Shevchuk Maria M. , Nanus David M. , Gudas Lorraine J.
Published: April 2023

Supplementary Table S1: shRNA sequences Supplementary Table S2: List of antibodies Supplementary Table S3: List of primer sequences Supplementary Figure S1: ChIP-seq analysis and hierarchical cluster analysis Supplementary Figure S2. Caki1, 786-O, and HK2 proliferation and Caki1 colony formation assays Supplementary Figure S3. Metabolomics analysis of RCC4 cells Supplementary Figure S4. TEM analysis of Caki1 cells Supplementary Figure S5. Western blot analysis of LC3 in Caki1, 786-O, and HK2 cells
supplemental legend from Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4–CHOP–DR5 Axis in Human Esophageal Cancer Cells
Authors: Chen Ping , Hu Tao , Liang Yupei , Li Pei , Chen Xiaoyu , Zhang Jingyang , Ma Yangcheng , Hao Qianyun , Wang Jinwu , Zhang Ping , Zhang Yanmei , Zhao Hu , Yang Shengli , Yu Jinha , Jeong Lak Shin , Qi Hui , Yang Meng , Hoffman Robert M. , Dong Ziming , Jia Lijun
Published: April 2023

supplemental legend
Supplementary Figure 3 from CADM1 Expression and Stepwise Downregulation of CD7 Are Closely Associated with Clonal Expansion of HTLV-I–Infected Cells in Adult T-cell Leukemia/Lymphoma
Authors: Kobayashi Seiichiro , Nakano Kazumi , Watanabe Eri , Ishigaki Tomohiro , Ohno Nobuhiro , Yuji Koichiro , Oyaizu Naoki , Asanuma Satomi , Yamagishi Makoto , Yamochi Tadanori , Watanabe Nobukazu , Tojo Arinobu , Watanabe Toshiki , Uchimaru Kaoru
Published: April 2023

PDF file - 29KB, Proportion of each subpopulation in the CADM1 vs. CD7 plot in normal controls.
Supplementary Figure 2 from CADM1 Expression and Stepwise Downregulation of CD7 Are Closely Associated with Clonal Expansion of HTLV-I–Infected Cells in Adult T-cell Leukemia/Lymphoma
Authors: Kobayashi Seiichiro , Nakano Kazumi , Watanabe Eri , Ishigaki Tomohiro , Ohno Nobuhiro , Yuji Koichiro , Oyaizu Naoki , Asanuma Satomi , Yamagishi Makoto , Yamochi Tadanori , Watanabe Nobukazu , Tojo Arinobu , Watanabe Toshiki , Uchimaru Kaoru
Published: April 2023

PDF file - 67KB, FISH analysis of HTLV-1-infected cells.
Supplementary Figure Legends from Prognostic B-cell Signatures Using mRNA-Seq in Patients with Subtype-Specific Breast and Ovarian Cancer
Authors: Iglesia Michael D. , Vincent Benjamin G. , Parker Joel S. , Hoadley Katherine A. , Carey Lisa A. , Perou Charles M. , Serody Jonathan S.
Published: April 2023

PDF file - 48K
Supplementary Figure S3 from Dysregulation of miR-212 Promotes Castration Resistance through hnRNPH1-Mediated Regulation of AR and AR-V7: Implications for Racial Disparity of Prostate Cancer
Authors: Yang Yijun , Jia Dingwu , Kim Hogyoung , Abd Elmageed Zakaria Y. , Datta Amrita , Davis Rodney , Srivastav Sudesh , Moroz Krzysztof , Crawford Byron E. , Moparty Krishnarao , Thomas Raju , Hudson Robert S. , Ambs Stefan , Abdel-Mageed Asim B.
Published: April 2023

Box-plot analysis of cDNA microarrays