bluuebunny/crossref_metadata_2025 huggingface dataset:
TAMAN POSYANDU AS INTEGRATED PUBLIC HEALTH PROGRAM
Authors: Febrianti Elisa
Published: October 2018

Taman Posyandu is a form of Community-Based Health Effort (UKBM) that develops an integration model such as  Integrated Service Post (Posyandu, Early Childhood Education (PAUD) and family building of children under five years old (BKB). These three components of ministers coordinate and work together. This study aims to find out the description of TamanPosyandu Cahaya Bangsa Kelurahan Medokan Semampir, Sukolilo Surabaya. The method in this research is qualitative descriptive.  The result of this research is Taman Posyandu Cahaya Bangsa has been in accordance with the guidance of the implementation of Taman Posyandu. PAUD and Posyandu activities have been running very well. However, BKB activities are still not maximized in service aspect. Health promotion strategies undertaken by Taman Posyandu Cahaya Bangsa are the empowerment, development of atmosphere and partnership. The empowerment of the Taman Posyandu Cahaya Bangsa has reached phase 3 because the target of empowerment has been able to innovate and be creative. Taman Posyandu Cahaya Bangsa has done the activity of developing atmosphere individually and group. Taman Posyandu Cahaya Bangsa partnered with Dinas Kesehatan Surabaya, Puskesmas Keputih, Midwife Village, Health Promotion, PERSAGI, HIMPAUDI and PKK.. Keyword: Taman Posyandu, Posyandu, BKB, PAUD, Surabaya
HUBUNGAN PERILAKU HIDUP SEHAT DENGAN STATUS KESEHATAN PADA MASYARAKAT KELURAHAN UJUNG
Authors: Sulistiarini Sulistiarini -
Published: October 2018

Health is a human right and one of the elements of welfare that must be realized. Individual or community health status is the result of interaction over the various factors both internal and external. The four main factors affecting the health status of the community are genetics, the environment such as social communities, economies, local politics and culture, and behaviors including individual lifestyles, as well as the health care facilities. Health status in Semampir District is low. Low health status caused by unhealthy behavior of the community. This research aimed to analyzed the relation between healthy life behavior with health status of the community in RW XIII Kelurahan Ujung, Kecamatan Semampir, Surabaya. This research used descriptive method with Simple Random Sampling technique, 136 respondents was selected as a sample. The independent variables in this research consisted of smoking behavior, physical activity or exercise, fruit and vegetables consumption behavior. The dependent variable is healthy status. The collected data were analyzed using Chi-square analysis, to determine the strong relationship of research subjects. The is a relationship relationship between vegetable consumption, fruit consumption and smoking behavior with health status bythe p value 0,009, 0,006 and 0,001 respectively as a result. Moreover there is no relationship between sports with health status by the result of p value is about 0.243.
Analisis Pemenuhan Standart Promosi Kesehatan Rumah Sakit di Rumah Sakit Islam Surabaya
Authors: Prahesti Monica Galih
Published: October 2018

Rumah Sakit Islam Surabaya memiliki tujuan untuk memberikan upaya promotif, preventative, kuratif, edukatif dan  rehabilitative. Maka dari itu peneliti bertujuan untuk menganalisis pelaksanaan Promosi Kesehatan Rumah Sakit (PKRS) di Rumah Sakit Islam Surabaya sesuai standart yang telah ditentukan oleh kementerian kesehatan sebagai salah satu upaya untuk mendukung tujuan tersebut. Penelitian ini bersifat observasional partisipatif, dimana peneliti melakukan observasi serta ikut berpartisipasi dalam kegiatan. Tempat penelitian yaitu di Rumah Sakit Islam Surabaya. Sumber informasi dalam penelitian ini adalah data sekunder dari Rumah Sakit dan data primer berupa wawancara kepada informan. Informan pada penelitian ini yaitu ketua PKRS tahun 2015 ketua PKRS tahun 2016, ketua bidang pemasaran dan petugas-petugas terkait. Panduan yang digunakan dalam wawancara dan observasi mengacu pada Standar PKRS oleh Pusat Promosi Kesehatan Tahun 2010 dan Permenkes RI Nomor 004 Tahun 2012 tentang Petunjuk Teknis Promosi Kesehatan Rumah Sakit. Hasil penelitian menunjukkan bahwa Rumah Sakit Islam Surabaya belum mempunyai tim khusus yang ditugaskan dalam pelaksanaan PKRS. Tim yang terbentuk terdiri dari petugas kesehatan yang memiliki tugas ganda selain mengemban tugas menjadi tim PKRS juga menjadi petugas kesehatan lain, misalnya dokter, perawat, bidan dll. Selain itu, dalam pelaksanaan kegiatan PKRS di Rumah Sakit Islam Surabaya belum sepenuhnya memenuhi standart acuan dari Standar PKRS oleh Pusat Promosi Kesehatan Tahun 2010. Oleh karena itu, Rumah Sakit Islam Surabaya disarankan untuk membentuk tim PKRS dari petugas kesehatan yang khusus ditugaskan untuk bertanggungjawab dalam kegiatan PKRS serta membuat jadwal pelaksanaan kegiatan PKRS di RSI Surabaya dengan rinci.
PENGARUH SUBSTITUSI TEPUNG KEDELAI, TEPUNG BEKATUL DAN TEPUNG RUMPUT LAUT (Gracilaria sp) TERHADAP DAYA TERIMA, ZAT BESI DAN VITAMIN B12 BROWNIES
Authors: Fibriafi Rahmasuci , Ismawati Rita
Published: October 2018

Soybean, rice bran and seaweed flour (Gracilaria sp) are food sources of iron and vitamin B12 so it is potential to be used as an ingredient for alfernative snack for childbearing age women with ovo vegetarian diet. This research intended to analyze effect of soybean, rice bran and seaweed flour (Gracliaria sp) substitution on the acceptability, iron and vitamin B12 content. This research was true experimental research with completely randomized design. There are 4 formulas with six times replications. Analysis of accessibility different used was friedman. Friedman Test and Wilcoxon Ranks Test. The untrained panelists were 25 childberaing age women with ovo vegetarian diet. The difference test showed that there were no difference in colour, aroma and texture. There was a difference (p<0,05) on flavour characteristic and  Wilcoxon Ranks Test showed that there was a difference (p<0,05) between control formula and substitution formula. Based on the result of acceptability, brownies substitution formula with the best score was F3 formula (flour 37.5 g, soybean flour 22.5 g, rice bran 75 g, and seaweed flour (Gracilaria sp) 15 g). The iron and vitamin B12 content of  F3 formula were 3.6 mg and 0.2 μg respectively on 100 gram formula and fulfill 10-15% of childbearing age women’s requirement. Finally, the best formula which obtained from its acceptability, iron and vitamin B12 content was F3 formula, so it could be an alternative snack for childbearing age women with ovo vegetarian diet.
HUBUNGAN STATUS GIZI DAN ASUPAN MAGNESIUM DENGAN KEJADIAN PREMENSTRUAL SYNDROME (PMS) PADA REMAJA PUTRI
Authors: Estiani Kartika , Nindya Triska Susila
Published: October 2018

Premenstrual Syndrome (PMS) is a combination of physical, psychological, and emotional disturbance which is related to menstrual cycle that appear 7 to 10 days before menstruation period and disappear when menstruation begins. Nutritional status and magnesium intake can cause premenstrual syndrome. The purpose of this study was to analyze the correlation of seed nutritional status and magnesium intake with premenstrual syndrome. The research used cross sectional study. The sample size was 99 female students in SMAN 4 Surabaya. The data were collected by measuring weight and height to obtain nutritional status variable; 2x24 hours  estimated food records to obtain magnesium intake; and questionnaire for premenstrual syndrome case. The data were analyzed using chi-square test. The results of this study showed that there was correlation  between nutritional status (p=0,036) and Premenstrual Syndrome (PMS). Besides that, there was also a correlation between magnesium intake (p=0,012) and Premenstrual Syndrome (PMS). Premenstrual Syndrome (PMS) can be caused by overweight and low magnesium intake. It is recommended for female students to prevent overweight status by monitoring their weight every month and increase their intake of high magnesium, food such as apple, spinach, and sweet potato.
FAKTOR RISIKO YANG BERHUBUNGAN DENGAN KEJADIAN BAYI BERAT LAHIR RENDAH DI KECAMATAN SEMAMPIR SURABAYA
Authors: Fajriana Amima , Buanasita Annas
Published: October 2018

Low Birth Weight (LBW) is one of the biggest causes of neonatal mortality in Indonesia. The prevalence of LBW at Semampir District in Surabaya tended to increase from 5.74% in 2013 to 13.65% in 2015. LBW caused by multi-factors including internal factors such as fetal, placental and maternal, and also external factors such as lifestyle and environment. This study aimed to analyze the association between maternal age, gestational age, Mid Upper-Arm Circumference (MUAC), Hemoglobin (Hb) levels, environmental tobacco exposure and LBW at Semampir District, Surabaya. The respondents were mothers at Semampir District who gave birth in 2016.  The design of this study was case control. The sample consisted of 22 mothers from the control group and 22 mothers from the case group. The result of descriptive analysis respectively showed that in case group (40.6%) and control group (13.6%) were not pregnant in healthy reproductive age. 59.1% and 18.1% gave birth when the gestational age <37 weeks. 41% and 9.1% were suffered of chronic energy malnutrition (MUAC <23.5). 40.9% and 22.7% were anemic. Moreover, 90,9% and 77,2% were exposed to tobacco smoke (secondhand smoke exposure). Chi square analysis with α=0,05 showed that there were significance associations between gestational age (p=0,006) (OR=6,198; CI 95%=1,61-27,88) and MUAC (p=0,018) (OR=6,623; CI 95%=1,327-51,2) with LBW. It is concluded that mother who gave birth to a premature baby were 6,2 times more likely to have LBW, whereas mother who suffered from chronic energy malnutrition were 6,6 times more likely to have LBW baby.
PENGARUH SUBSTITUSI UBI JALAR KUNING, ISOLAT PROTEIN KEDELAI, DAN TEPUNG DAUN KELOR TERHADAP KANDUNGAN GIZI SERTA DAYA TERIMA MI INSTAN
Authors: Agus Ranty Restiartanti , Ismawati Rita
Published: October 2018

Instant noodle is an alternative source of energy based on wheat fl our. The consumption of instant noodle in Indonesia is quite high. Instant noodle innovation with local food substitution is a solution to reduce dependence on wheat flour. Yellow sweet potato has an energy value similar to wheat fl our, as well as isolated soy protein high in protein and moringa leaves powder high in calcium. The purpose of this research was to analyse the effect of yellow sweetpotato, isolated soy protein, and moringa leaves powder substitution on acceptability and nutritional value (energy, protein, and calcium) of instant noodle. This was experimental research with completely randomized design. There were three formulas, one as a control formula (F0) and two substitution formulas with yellow sweet potato, isolated soy protein, and moringa leaves (F1 and F2) with 8 repetitions. There were 33 pregnant women as untrained panelist. The difference test was analyzed by Kruskall Wallis and Mann Whitney (α≤0.05). The result of panelist acceptability showed that the best formula is F2 (substitution of 6.8% yellow sweet potato, 5.4% isolated soy protein, and 1.4% moringa leaves powder). There was a signifi cant difference between F0 with F2 (p=0.004) and F1 with F2 (p=0.013) on aroma characteristics. The highest protein and calcium content per 100 g of instant noodle was F2, with 14 g and 44.5 mg. The best formula which determinated by the acceptability and nutritional value (energy, protein and calcium) was F2 (substitution of 25 g yellow sweet potato, 20 g isolated soy protein, and 5 g moringa leaves powder), so it can be used as an alternative food for pregnant women.
DAYA TERIMA DAN ZAT GIZI PANCAKE SUBSTITUSI KACANG MERAH (PHASEOLUS VULGARIS L) DAN DAUN KELOR (MORINGA OLEIFERA) SEBAGAI ALTERNATIF JAJANAN ANAK SEKOLAH
Authors: Heluq Dinda Zhara , Mundiastuti Luki
Published: October 2018

Nutritional problems among school aged children are still found in Indonesia. This problems caused by poor eating habit, such as the low consumption of vegetables and high consumption of snacks which only contain the high energy,fat, and sugar yet low in protein and micro nutrients. Improving the quality of snacks can be conducted to overcome the nutrition problems. This research was aimed to analyze the effect of substitution of red beans and moringa leavesto the acceptance and nutrient content (protein and calcium) in pancakes. This was an experimental study with the Completely Randomized Design. Five with repetitions with three formulas, i.e., a control formula and two modifi cationformulas (substituted with red beans and moringa leaves). The untrained panelist were 30 students of the fi fth-grade elementary school. Data was analyzed by Friedman and Wilcoxon Sign Rank (α=0.05) tests. The acceptance level demonstrated that the F1 was the most preferred formula by the panelists. There were no signifi cant differences in the aroma, fl avour, and texture (p>0.05) between formulas. Nonetheless, there was a signifi cant difference in color (p<0.05) between F0 and F1. The laboratory test showed that the protein and calcium content per 100 g of the F1 were, 5.27 g (7% higher than the F0) and 254,8 mg (304% higher than the F0) respectively. The F1 was the chosen formula because it had better acceptability and nutrient content than the control formula. The best acceptance, but also had. Thus, it is potential to become an alternative snack for school aged children.
DUKUNGAN ORANG TUA KEPADA REMAJA DI KOTA BOGOR UNTUK MENGONSUMSI SAYUR DAN BUAH
Authors: Lubis Asri Christine , Sekarasih Laras
Published: October 2018

Compared to children in other cities and towns in the West Java province, adolescents aged 10–14 in Bogor have the lowest rate of vegetable and fruit intake. One primary factor that affects adolescents’ vegetable and fruit intake is parental support. This qualitative descriptive research aimed to analyse parental support for adolescents’ vegetable and fruit intake in Bogor. Fifteen parents whose child studied at a public junior high school in Bogor participated in semi-structured interviews. Findings showed that children’s vegetables and fruits consumption was lower than the Ministry of Health’s recommendation. All parents reported that they provided instrumental support for their childrento eat vegetables and fruits at each meal time and provided vegetables and fruits (cooked or bought), but most did not teach or involve their children in preparing vegetables and fruits. Most parents asked their children’s food intake and reminded them to eat more vegetables and fruits as a form of emotional support. However, they did not persuade their children when the latter refused to eat vegetable and fruit. Additionally, parents also did not provide positive feedback for their children when they showed willingness to try to eat vegetables and fruits. Parents seemed to be more lenient in controlling children’s intake of fast food, including purchasing fast foods for their children. The fi ndings suggest a need for an initiative or program that aims at increasing parental support, which necessitates intervention to improve parental support. It is recommended to conduct further research to investigate the predictors of parental support.
PENINGKATAN PENGETAHUAN IBU BALITA MELALUI PENGENALAN PROGRAM KADARZI DI KELURAHAN WONOKUSUMO SURABAYA
Authors: Rachmayanti Riris Diana
Published: October 2018

The implementation of the KADARZI program has not been maximized due to the many families who do not know and do not understand the existence of the program. One area with low knowledge about the KADARZI program isthe Wonokusumo Surabaya district. The purpose of this study was to analyze the improvement of mother knowledge after given an intervention in the Wonokusumo Sub-district of Surabaya and to identify factors that causing nutrition problems of children under fi ve (predisposing, reinforcing and enabling). This was a pre-experimental study with one group pretest-posttest design. The study was conducted in RW 02 Wonokusumo Village, January-February 2017. Data collection was carried out quantitative and qualitatively. A total of 38 mothers had children under fi ve and present at the posyandu in RW 2 were sampled in this study. Mother knowledge before and after the intervention were collected qualitatively. Paired sample t-test was used to analyze the differences. The qualitative data were collected through observation and in-depth interview to the head of RW 1 person and cadre (8 people). Interventions of health education using leafl et, video and simulation of making modisco (as one way to create and process nutritious local food). Intervention was conducted one time during the Posyandu. Activities were held once with 4 hours duration. The results showed that the knowledge score was increased from 47.9 to 82.6 there was a signifi cant increase in knowledge between before and after the intervention (p=0.043). The causes of nutritional problems in children under fi ve were 3 factors: predisposing, reinforcing, enabling. Health education interventions can improve maternal knowledge aboutthe nutritional fulfi llment of children under five and the KADARZI program
Sorption to Biochar Impacts β-Glucosidase and Phosphatase Enzyme Activities
Authors: Foster Erika J. , Fogle Emily J. , Cotrufo M. Francesca
Published: October 2018

Extracellular enzymes catalyze biogeochemical reactions in soil, cycling carbon and nutrients in agricultural systems. Enzymes respond quickly to soil management, including organic amendment inputs, such as biochar, a charcoal-like solid byproduct of bioenergy production. In a previous agricultural field trial, a pine biochar amendment caused an approximately 40% decrease in the enzyme activities of β-glucosidase (BG) and phosphatase (PHOS). The large surface area of the pine biochar has the potential to sorb nutrients and other organic molecules. To test if sorption caused decreased enzyme activity, we used a laboratory assay to quantify the activity of two sorbed enzymes: BG and acid PHOS, involved in the cycling of carbon and phosphorous. The enzymes were incubated with three solid phases: (1) the high surface area pine biochar, (2) the agricultural soil, and (3) a low surface area grass biochar, for an additional comparison. We quantified the sorbed enzymes at pH 6, 7, and 8, using a Bradford protein assay, and measured the immobilized enzyme activities via high-throughput fluorometric analysis. After sorption onto pine biochar, detectable BG and PHOS activity levels dropped by over 95% relative to the soil, supporting direct sorption as one mechanism that reduces enzyme activity in biochar amended soil. This laboratory assay demonstrated that sorption could account for the lack of priming of native soil organic matter and changes in soil phosphorous cycling after pine biochar addition.
Global Recognition that Ecosystems Are Key to Human Resilience in a Warming World
Authors: Seddon Nathalie , Daniels Elizabeth , Davis Rowan , Harris Rian , Hou-Jones Xiaoting , Huq Saleemul , Kapos Valerie , Mace Georgina M. , Rizvi Ali Raza , Reid Hannah , Roe Dilys , Wicander Sylvia
Published: October 2018

Ecosystems are not merely vulnerable to climate change but, if sustainably restored and protected, are a major source of human resilience. Not only is the science evidence-base for this perspective growing rapidly, but ecosystems are featuring with increasing prominence in global climate change policy. Of 167 climate pledges submitted by the signatories of the Paris Climate Change Agreement (representing 194 nations), 103 include commitments to the restoration, management or protection of natural habitats in their adaptation strategies (of which 70 are aimed at protecting human communities from climate change hazards, i.e. ecosystem-based adaptation). A further 27 describe similar actions in their mitigation plans. In total, 65% of Paris Agreement signatories commit to restoring and/or protecting natural ecosystems. However, commitments rarely translate into robust science-based targets. As the world takes stock of the Agreement in 2018 and climate pledges are revised, we urge the science community to work closely with policy makers to identify meaningful adaptation targets that benefit both people and the ecosystems on which they depend.
On the Degenerate $(h,q)$-Changhee Numbers and Polynomials
Authors: Kim Yunjae , Park Jin-Woo
Published: October 2018

In this paper, we investigate a new $q$-analogue of the higher order degenerate Changhee polynomials and numbers, which are called the Witt-type formula for the $q$-analogue of degenerate Changhee polynomials of order $r$. We can derive some new interesting identities related to the degenerate $(h,q)$-Changhee polynomials and numbers.
Implementing Vertical Farming at University Scale to Promote Sustainable Communities: A Feasibility Analysis
Authors: Zhang He , Asutosh Ashish , Hu Wei
Published: October 2018

The world is facing several global issues such as food and energy crisis, climate change and greenhouse gases emissions. To subdue these issues, many entities from academia and industries have innovated alternate techniques of performing regular activities which cause such problems. One of these innovations is the introduction of vertical and zero acreage farming in the field of sustainability. These carry the potential to solve one of the most important affairs of food security in most countries of the world. But, this technology has been in its nascent stage for many years. This paper uses a comprehensive framework proving the feasibility of initiating vertical farming on university campuses to feed the staff and students, which could also set an example to the rest of the world into using this technique on a wider scale. The study chose Huazhong University of science and technology (HUST) in Wuhan city, China for accessing the return on investment and food sufficiency if vertical farming is implemented. Using Central Limit Theorem, a statistical model was developed, and various scenarios were analyzed. The results indicated that if a separate vertical farm is constructed, the breakeven can be achieved in a range of 10-20 depending on parameters such as type of operation, number of floors and amount of vegetation. The study has shown that the use of vertical farming cannot only bring in revenue for the campus but also aid in mitigating climate change.
Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment
Authors: Kuznetsov Konstantin A. , Stepanova Alena O. , Kvon Ren I. , Douglas Timothy E.L. , Kuznetsov Nikita A. , Chernonosova Vera S. , Zaporozhchenko Ivan A. , Kharkova Maria V. , Romanova Irina V. , Karpenko Andrey A. , Laktionov Pavel P.
Published: October 2018

Paclitaxel is a natural, highly lipophilic anti proliferative drug widely used in medicine. We have studied the release of tritium-labeled paclitaxel (3H-PTX) from matrices destined for the coating of vascular stents and produced by the electrospinning method from the solutions of polycaprolactone (PCL) with paclitaxel (PTX) in hexafluoisoropropanol (HFIP) and/or solutions of PCL with PTX and human serum albumin (HSA) in HFIP or HIFP-dimethyl sulphoxide (DMSO) blend. The release of PTX has been shown to depend on the solvent and the composition of electrospinning solution, as well as the composition of the surrounding medium, particularly the concentration of free PTX and PTX-binding biomolecules present in human serum. It was shown that 3D matrices can completely release PTX without weight loss. Two-phase PTX release from optimized 3D matrices was obtained: ~27% of PTX was released in the first day, another 8% were released over the next 26 days. Wherein ~2.8%, ~2.3%, and ~0.25% of PTX was released on day 3, 9, and 27, respectively. Considering PTX toxicity, the rate of its diffusion through the arterial wall, and the data obtained the minimum cytostatic dose of the drug in the arterial wall will be maintained for at least three months.
A Mobile Positioning Method Based on Deep Learning Techniques
Authors: Wu Ling , Chen Chi-Hua , Zhang Qishan
Published: October 2018

This study proposes a mobile positioning method which adopts recurrent neural network algorithms to analyze the received signal strength indications from heterogeneous networks (e.g., cellular networks and Wi-Fi networks) for estimating the locations of mobile statioThis study proposes a mobile positioning method which adopts recurrent neural network algorithms to analyze the received signal strength indications from heterogeneous networks (e.g., cellular networks and Wi-Fi networks) for estimating the locations of mobile stations. The recurrent neural networks with multiple consecutive timestamps can be applied to extract the features of time series data for the improvement of location estimation. In practical experimental environments, there are 4,525 records, 59 different base stations, and 582 different Wi-Fi access points detected in Fuzhou University in China. The lower location errors can be obtained by the recurrent neural networks with multiple consecutive timestamps (e.g., 2 timestamps and 3 timestamps); the experimental results can be observed that the average error of location estimation was 9.19 meters by the proposed mobile positioning method with 2 timestamps.
Data Censoring with Set-Membership Affine Projection Algorithm
Authors: Moradi Hamid Reza , Zardadi Akram
Published: October 2018

In this paper, the set-membership affine projection (SM-AP) algorithm is utilized to censor non-informative data in big data applications. To this end, the probability distribution of the additive noise signal and the excess of mean-squared error (EMSE) in steady-state are employed in order to estimate the threshold parameter of the single threshold SM-AP (ST-SM-AP) algorithm aiming at attaining the desired update rate. Furthermore, by defining an acceptable range for the error signal, the double threshold SM-AP (DT-SM-AP) algorithm is proposed to detect very large errors due to the irrelevant data such as outliers. The DT-SM-AP algorithm can censor non-informative and irrelevant data in big data applications, and it can improve misalignment and convergence rate of the learning process with high computational efficiency. The simulation and numerical results corroborate the superiority of the proposed algorithms over traditional algorithms.
Solanum Fruit Juice as a Natural and Sustainable Source of Antioxidants for Patients with Chronic Hepatitis C under Antiviral Therapy
Authors: Iheka Chidiebere Uchenna , Osuoha Justice Obinna , Archibong Idongesit Ekong , Amadi Peter Uchenna , Adeoti Oluwatoyin Taiwo
Published: October 2018

Variations in liver metabolism as a result of hepatitis C virus have been established by numerous clinical trials. The use of antioxidants supplements has been reported to minimize the implication of this disease. In this regard, we examined the suitability of Solanum fruit juice, a natural source of vitamin C and citrus flavoniod as a precursor for the treatment of patients with chronic hepatitis C. Forty adult patients who were diagnosed with chronic hepatitis C and were under antiviral therapy were divided into two equal groups. Group 1 patients received their antiviral therapy with normal food and water and served as the control group while patients in group 2 were supplemented with Solanum fruit juice for eight consecutive weeks. Measurements for Anthropometric data, C reactive protein (CRP), atherogenic indices, biochemical parameters and activities of liver marker enzymes were recorded before and after eight weeks. No alterations were found in waist circumference, body mass and body fat following regular use of Solanum fruit juice. The serum levels of oxidative stress markers, LDL-cholesterol, total cholesterol, CRP and atherogenic indices decreased in the Solanum fruit juice group when compared to the control group. Moreover, the activities of the liver marker enzyme AST decreased in those who had high levels before the intervention. These results underscore the benefits of Solanum fruit juice in the diet of patients with HCV as a result of decreased cholesterol in blood serum, decreased inflammation, and increase in antioxidant capacity as well as maintaining body mass index. This clinical trial is registered at Pan African Clinical Trial Registry (www.pactr.org) with unique identification number PACTR201802003092138.
Assimilation of Sentinel-2 Data into a Snowpack Model in the High Atlas of Morocco
Authors: Baba Mohamed Wassim , Gascoin Simon , Hanich Lahoucine
Published: October 2018

The snow melt from the High Atlas is a critical water resource in Morocco. In spite of its importance, monitoring the spatio-temporal evolution of key snow cover properties like the snow water equivalent remains challenging due to the lack of in situ measurements at high elevation. Since 2015, the Sentinel-2 mission provides high spatial resolution images with a 5 day revisit time, which offers new opportunities to characterize snow cover distribution in mountain regions. Here we present a new data assimilation scheme to estimate the state of the snowpack without in situ data. The model was forced using MERRA-2 data and a particle filter was developed to dynamically reduce the biases in temperature and precipitation using Sentinel-2 observations of the snow cover area. The assimilation scheme was implemented using SnowModel, a distributed energy-balance snowpack model and tested in a pilot catchment in the High Atlas. The study period covers 2015-2016 snow season which corresponds to the first operational year of Sentinel-2A, therefore the full revisit capacity was not yet achieved. Yet, we show that the data assimilation led to a better agreement with independent observations of the snow height at an automatic weather station and the snow cover extent from MODIS. The performance of the data assimilation scheme should benefit from the continuous improvements in MERRA-2 reanalyses and the full revisit capacity of Sentinel-2.
Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs as Novel Tools for Non-Invasive cell Assays
Authors: Ruthenbeck Alexandra , Marangoni Elisa , Diercks Björn-Ph. , Krüger Aileen , Nikolaev Viacheslav O. , Guse Andreas H. , Meier Chris
Published: October 2018

Adenine nucleotide (AN) 2nd messengers such as 3’,5’-cyclic adenosine monophosphate (cAMP) are central elements of intracellular signaling, but many details of underlying processes remain still elusive. Like all nucleotides, cyclic nucleotide monophosphates (cNMPs) are net-negatively charged at physiologic pH which limits their applicability in cell-based settings. Thus, many cellular assays rely on sophisticated techniques like microinjection or electroporation. This setup is not feasible for medium- to high-throughput formats, and the mechanic stress that cells are exposed to raises the probability of interfering artefacts or false-positives. Here, we present a short and flexible chemical route yielding membrane-permeable, bio-reversibly masked cNMPs for which we employed the octanoyloxybenzyl (OB) group. We further show hydrolysis studies on chemical stability and enzymatic activation, and present results of real-time assays, where we used cAMP and Ca2+ live cell imaging to demonstrate high permeability and prompt intracellular conversion of some selected masked cNMPs. Consequently, our novel OB-masked cNMPs constitute valuable precursor-tools for non-invasive studies on intracellular signaling.
Nano-Mediated Photodynamic Therapy for Cancer: Enhancement of Cancer Specificity and Therapeutic Effects
Authors: Mfouo Tynga Ivan , Abrahamse Heidi
Published: October 2018

Deregulation of cell growth and development lead to cancer, a severe condition that claims millions of lives worldwide. Targeted or selective approaches used during cancer treatment determine the efficacy and outcome of the therapy. In order to enhance specificity and targeting and better treatment options for cancer, novel and alternative modalities are currently under development. Photodynamic therapy has the potential to eradicate cancer and combination therapy would yield even greater outcomes. Nanomedicine-aided cancer therapy shows enhanced specificity for cancer cells and minimal side-effects coupled with effective cancer destruction both in vitro and in vivo. Nanocarriers used in drug-delivery systems are well able to penetrate cancer stem cell niche, simultaneously killing cancer cells and eradicate drug-resistant cancer stem cells, yielding therapeutic efficiency up to 100 fold against drug-resistant cancer in comparison with free drugs. Safety precautions should be considered when using Nano-mediated therapy as the effects of extended exposure to biological environments are still to be determined.
Case Study of 5 Lateral TAML-3 Well Construction to Target PK 1-3 Layers
Authors: Brednev Philipp , Zavyazkin Dmitry , Voronin Andrey , Eremeev Dmitry , Dergunov Andrey
Published: October 2018

This article describes experience and results of TAML-3 penta-lateral (5-lateral) Fishbone type well construction at East-Messoyakha field. Trial work has been conducted to determine technical and economical feasibility of fishbone well construction.

East - Messoyakha field has very complex geological structure. According to field sedimentary conditions there are 3 major deposition cycles in primary PK 1-3 formation - «А», «B» и «С». Cyclite «B» has a high degree of discontinuity that leads to low production efficiency of horizontal wells.

Hydrodynamic modelling has shown multilateral well technology to be perspective in terms of increase of vertical association coefficient. Utilization of multilateral well technology is very perspective in geological conditions of East-Messoyakha field, it will also increase efficiency of reserves development compared to conventional horizontal wells.

During completion concept selection and planning stage, different options have considered. TAML-3 level have been selected for a multilateral junction. Lateral trajectories well paths were planned to cross sub-layers and turn in azimuthal direction.

Multilateral ERD well construction required multiple technical solutions to be implemented in order to successfully complete the project: running 7" casing in 800 horizontal section, utilization of OBM and its re-use, running lateral liners in two trips.

Successful project execution of penta-lateral allows to solve the following challenges:extend reservoir coverage and increase of effective well radius in heterogeneous layerssimultaneous drainage in different layersdecrease the risk of production loss due to lateral hole collapse

Cased fishbone multilateral well proved its effectiveness after 6-months production. It is also a logical continuation of company’s technological development. The paper also discusses possible options for further advancement.
Önkormányzati sportstratégiák
Authors: Bukta Zsuzsanna
Published: October 2018

Az önkormányzatok sportban betöltött szerepét már az 1992-ben megalkotott Európai Sport Charta is hangsúlyozta. Európa szinte valamennyi országában jelentős a helyi önkormányzatok szerepe, a helyi sporttevékenységet általában helyzetelemzés és stratégiai tervezés kíséri. Magyarországon az önkormányzatoknak törvényi kötelezettsége a sportfeladataik rendeletben való megfogalmazása, amely lehetőséget nyújt arra, hogy a különböző adottságokkal és lakossági igényekkel rendelkező városok megtervezzék és rendszerezzék sportban vállalt feladataikat. Vizsgálatunk célja, hogy ezeknek a koncepcióknak a hatékonyságát felmérjük a dokumentumelemzés módszerével. Jelen tanulmány a holland sportirányítási rendszer elemzéséből, valamint egy holland város, Leusden sportstratégiájából kiindulva hazai városok sportkoncepcióit elemzi négy szempont alapján. A stratégiákat megalapozó felmérések megléte, a hátrányos helyzetűekkel kapcsolatos intézkedések, a stratégiák élsporttal foglalkozó tartalma, valamint a konkrét lépések, beavatkozási pontok azonosítása képezte a vizsgálat tárgyát, nyolc hazai város esetében. Az elemzések kapcsán megállapítható, hogy a hazai városok koncepcióihoz nem készültek lakossági felmérések, a helyzetelemzések és a javaslatok nem az egyes célcsoportok igényeire alapozottak, kevés szó esik a hátrányos helyzetűekről. A magyar koncepciók jelentős mértékben foglalkoznak a helyi élsport tevékenységgel, és változó mértékű a konkrét programok tételes megfogalmazása.
A „Rajzolj egy fogyatékos embert” teszt alkalmazásának lehetőségei a pedagógiában
Authors: Tiszai Luca , Kocsisné Kálló Veronika
Published: October 2018

A szerzők a fogyatékosság iránti attitűd feltárásának lehetőségeit vizsgálták projektív rajztesztek segítségével. Egy fogyatékos emberrel való találkozás intenzív érzelmi tapasztalat, amelyben számos intraperszonális konfliktus van jelen, amelyek feltárása társadalmi tabuk miatt nehézségekbe ütközik. A vizsgálat során 116 rajzról kérdezték meg különböző szakértők véleményét. A kapott eredményeket egy olyan összeállított szempontsor szerint elemezték, mely a rajzokról alkotott benyomások, vélemények, elemző reflexiók szerint visszatérő és tipizálható mintázatokat mutat, majd a kapott mintázatokat szakirodalmi forrásokkal vetették össze. Az elemzés nem vette figyelembe a rajzkészség megítélését, hiszen valamennyi rajzoló 18 év feletti ép intellektusú személy, valamint a rajzolásra fordított idő többletinformációt hordoz az attitűd lehetséges megfigyelése és érékelése tekintetében. Az elemzés során különböző fogyatékossággal kapcsolatos attitűdökkel, sztereotípiákkal azonosítható rajzi jegyeket találtak, mint izoláció, alacsonyabb vagy egyenlő társadalmi státus, gyermekként való kezelés, személyközpontú vagy problémaközpontú megközelítés. A rajzokból az attitűd érzelmi komponenseire, a rajzoló a fogyatékossággal kapcsolatos érzelmeire is következtetni enged. A rajzi válaszok többértelműsége és komplexitása miatt pedagógiai alkalmazás során a rajz értelmezéséhez elengedhetetlenül szükséges a rajzolónak a rajzoláskor aktuális, kontextuális állapotának értelmezése. A teszt szerepe a pedagógiai kutatásban és a gyakorlati munkában egyaránt a fogyatékossággal kapcsolatos attitűd a maga komplexitásában való kifejezésének lehetősége, és a rejtett, vagy nehezen verbalizálható tartalmak kimondhatóvá tétele.
Tudás és innováció: a felnőttkori tanulás kutatásának változatos útjai
Authors: Káplár-Kodácsy Kinga
Published: October 2018

Recenzió a Journal of Adult Learning, Knowledge and Innovation (2017) című folyóiratról.
A gyermekkor értelmezési lehetőségei a fejlődésközpontú- és az új szociológiai paradigma mentén
Authors: Czető Krisztina
Published: October 2018

A tanulmány a gyermekkor koncepciójához kapcsolódóan az elsősorban szociológiai kötődésű tudományos diskurzus két pólusa, a fejlődésközpontú- és új szociológiai paradigmák mentén tárja fel a gyermekkor értelmezési lehetőségeit. A két paradigma alapjaiban határozza meg a 21. században jelen lévő gyermekkor konstrukciókat. A gyermekkor krízisét leíró megközelítések sok esetben valójában a modernitás által létrehozott gyermekkor képéhez visszalépő, értékelő viszonyulások, kétségtelen ugyanakkor, hogy a késő-modern kor hozta gazdasági, kulturális és társadalmi változások újrakonstruálják a gyermekkort. A tanulmány célja ennek a kettőségnek a feltárása és értelmezése.
5. és 6. évfolyamos tanulók nemzeti szimbólumokkal kapcsolatos ismereteinek jellemzői – egy technológia alapú mérés tanulságai
Authors: Dancs Katalin
Published: October 2018

A tantervi dokumentumokban célként jelenik meg a nemzeti identitás fejlesztése, azonban arra vonatkozóan nem rendelkezünk információkkal, hogy milyen jellemzői vannak a tanulók nemzeti identitásának. Kutatásunkban azt a célt tűztük ki, hogy mérjük a tanulók teljesítményét a nemzeti identitással összefüggő ismeretelemekkel, a nemzeti szimbólumokkal kapcsolatban. A nemzeti szimbólumok a nemzeti kultúra elemei, a történeti narratívákban helyet kapó személyek, események, helyszínek vagy tárgyi alkotások. Több lépésben meghatároztuk a tantervekben szereplő nemzeti szimbólumokat, majd ezek felhasználásával tesztet készítettünk. Eredményeink szerint tesztünk segítségével jellemezni tudjuk a tanulók tudását, átlagosan 64,78%-os teljesítményt értek el. Az idősebb tanulók jobban teljesítettek, míg a nemek között nem találtunk különbséget. A nemzeti identitás elemei közül vizsgáltuk a tanulók azonosulásának erősségét is. A 6. évfolyamosok gyengébb azonosulást tanúsítottak, nemi különbséget ebben az esetben sem találtunk. Megvizsgáltuk a teszteredmények és az azonosulás erőssége közötti kapcsolatot is. Mindkét évfolyamon kapcsolat mutatható ki a változók között, azonban az együtt járás mértéke alacsony. A tanulók teljesítménye ugyanakkor korrelál az iskolai teljesítményükkel való elégedettségükkel, ami megerősíti, hogy a tananyagban helyet kapó ismereteket mérte tesztünk. Számítógép-alapú mérésünk lehetővé tette, hogy a tesztkitöltés körülményeiről is adatokat gyűjtsünk. Nem találtunk összefüggést a tanulók teljesítménye és tesztre fordított ideje között, azonban az idő és az iskolába járás iránti pozitív attitűd között igen. Ez az eredmény azt erősíti meg, hogy nem a tanulók tudás szintje befolyásolja a kitöltésre fordított időt, hanem inkább attitűdjeik befolyásolják azt. Kutatásunk az első lépés volt annak érdekében, hogy megismerjük az iskola identitáskonstrukcióban betöltött szerepét.
Critical elements for local Indigenous water security in Canada: a narrative review
Authors: Latchmore Tessa , Schuster-Wallace C. J. , Longboat Dan Roronhiakewen , Dickson-Anderson Sarah E. , Majury Anna
Published: October 2018

Indigenous communities in Canada are over-represented with respect to poor water quality and water advisories. To date, approaches to solve this water crisis have been founded in the Western Science (WS) context with little to no consultation or dialogue with those communities most impacted, and without regard for culture. A literature review was undertaken to: (i) document Indigenous Knowledge (IK), and perspectives regarding water and (ii) to identify current local water security tools utilized by Indigenous communities. The aim is to provide sound evidence regarding the value of ownership and leadership by Indigenous communities in the context of current and appropriate resources available to (re)claim these roles. Solutions must remain consistent with, and founded upon, traditional Indigenous worldviews and cultural values to ensure sustainable water security. Literature reviewed from the past ten years revealed one overarching creation theme with three water-specific themes in Indigenous communities; namely, water from natural sources, water as a life-giving entity, and water and gender. Ultimately, there needs to be a new framing of local water security with the development of tools which engage IK and WS in order to assess local water security and appropriately inform interventions, policies, regulations and legislation.
Rotavirus analyses by SYBR Green real-time PCR and microbiological contamination in bivalves cultivated in coastal water of Amazonian Brazil
Authors: Marinho A. N. R. , Rocha D. C. C. , Kanai Y. K. , Alves C. M. , Costa D. C. , Sousa A. H. , Barros B. C. V. , Bonfim M. C. M. S. , Mascarenhas J. D. P.
Published: October 2018

The contamination of mussels and oysters by viruses and bacteria is often associated with water contamination and gastroenteritis in humans. The present study evaluated viral and bacterial contamination in 380 samples, from nine mollusk-producing regions in coastal water north of the Brazilian Amazon. Rotavirus contamination was studied for groups A to H, using a two-step SYBR Green RT-qPCR (quantitative reverse transcription polymerase chain reaction), and bacterial families Enterobacteriaceae, Vibrionaceae, and Aeromonadaceae by classical and molecular methods. From the 19 pools analyzed, 26.3% (5/19) were positive for group A Rotavirus, I2 genotype for VP6 region, without amplifications for groups B–H. Bacteriological analysis identified Escherichia coli isolates in 89.5% (17/19) with identification of atypical enteropathogenic E. coli aEPEC in 10.5% (2/19), Salmonella (Groups C1 and G) (10.5%, 2/19), Vibrio alginolyticus (57.9%, 11/19) V. parahaemolyticus (63.2%, 12/19), V. fluvialis (42.1%, 8/19), V. vulnificus (10.5%, 2/19), V. cholerae non-O1, non O139(10.5%, 2/19) and Aeromonas salmonicida (52.6%, 10/19). All the samples investigated presented some level of contamination by enterobacteria, rotavirus, or both, and these results may reflect the level of contamination in the Northern Amazon Region, due to the natural maintenance of some of these agents or by the proximity with human populations and their sewer.
Cryptosporidium genotyping and land use mapping for hazard identification and source tracking in a small mixed rural–urban watershed in Southeastern Brazil
Authors: Andrade Rosane C. , Bastos Rafael K. X. , Bevilacqua Paula D. , Andrade Rosângela V.
Published: October 2018

Cryptosporidium, faecal indicator organisms and physical and chemical water quality variables were monitored in a small mixed rural–urban watershed in southeastern Brazil. Cryptosporidium was present in 43% of 117 water samples analysed by microscopy. Concentrations varied from non-detects to 14 oocysts L−1. All samples were further analysed by nested-PCR, and Cryptosporidium spp. were detected in 24% (28) of them. Sequencing at the 18S rRNA locus gave high quality sequences in eight samples, revealing the presence of Cryptosporidium parvum. Cryptosporidium was not correlated with faecal indicator organisms (total coliforms, Escherichia coli, Enterococcus and coliphages), nor with physical and chemical water quality variables (e.g. turbidity, electrical conductivity and chemical oxygen demand), but it was with farm animal density (number of animals per ha). Land use mapping reinforced the suggestions from Cryptosporidium genotyping that both animals (livestock) and humans are potential sources to environmental contamination with oocysts within the watershed.
Biosorption of zinc from aqueous solution by cyanobacterium Fischerella ambigua ISC67: optimization, kinetic, isotherm and thermodynamic studies
Authors: Safari Moein , Ahmady-Asbchin Salman
Published: October 2018

In this present study, biosorption of Zn(II) from aqueous solution by cyanobacterium Fischerella ambigua was investigated in batch experiments. The effects of pH, bacterial dosage, initial Zn(II) concentration, contact time and temperature were studied. Removal process was inﬂuenced signiﬁcantly by the variation of pH, biosorbent concentration, initial Zn(II) ion concentration, temperature and contact time. Optimum biosorption conditions were found to be initial pH of 5, bacterial dosage of 0.2 g/l and initial Zn(II) ion concentration of 175 mg/l at room temperature and contact time of 90 min. The maximum uptake capacity of F. ambigua for Zn(II) ions was found to be 98.03 mg/g at optimum conditions. The correlation coefficient for the second-order kinetic model was 0.995. The Freundlich isotherm model showed better ﬁt to the equilibrium of the system, compared with the Langmuir model. Fourier transform infrared analysis of bacterial biomass revealed the presence of carboxyl, hydroxyl, sulfite and amino groups, which are likely responsible for the biosorption of Zn(II). The negative values of Gibbs free energy, ΔG°, conﬁrm the spontaneous nature of the biosorption process. Finally, F. ambigua adsorption capacity was compared with other biosorbents. Results showed that F. ambigua was an efficient biosorbent in the removal of Zn(II) ions from an aqueous solution.