bluuebunny/crossref_metadata_2025 huggingface dataset:
Response of Moringa oleifera Seeds and Fixed Oil Production to Vermicompost and NPK Fertilizers under Calcareous Soil Conditions
Authors: Atteya Amira K. G. , Albalawi Aishah N. , El-Serafy Rasha S. , Albalawi Khalil N. , Bayomy Hala M. , Genaidy Esmail A. E.
Published: September 2021

A shortages of soil nutrients resources and a lack of accessibility to them especially in calcareous soil are considered some of the main factors that limit plant production. In particular, the cultivation of the Moringa oleifera trees in this type of soil is of special interest given the increasing demand for every part of this tree. Several studies have focused on the production of its leaves as an herbaceous plant and not as a tree, but there has not been extensive research on its pods, seeds, and fixed oil production. In this sense, in this study, we provide an assessment of the use of fertilizers, vermicompost and NPK (as traditional minerals and as nanoparticles), in order to improve pods, seeds, and fixed oil contents, as indicators of the quality of the production of the Moringa oleifera trees in calcareous soil conditions. In this experiment, it was observed that all parameters and the yield of pods, seeds, and fixed oil of the Moringa oleifera tree were significantly improved by increasing the level of vermicompost and using NPK fertilization and combination treatments in both seasons of the study. The combination treatments of 10 and 20 ton ha−1 vermicompost plus NPK control produced the highest percentage of oleic acid with insignificant differences between them.
Role of Different Abiotic Factors in Inducing Pre-Harvest Physiological Disorders in Radish (Raphanus sativus)
Authors: Manzoor Ayesha , Bashir Muhammad Ajmal , Naveed Muhammad Saqib , Cheema Kaiser Latif , Cardarelli Mariateresa
Published: September 2021

Radish, one of the important root vegetables, is widely grown in the world due to its easy cultivation, short duration, growing habit, and adaptability to various growing conditions. However, it is still extremely difficult to produce good quality radish roots due to its vulnerability to different preharvest physiological disorders. Important physiological disorders that significantly reduce the yield and quality of radish are forking, pithiness/sponginess, cracking/splitting, hollowness, and internal browning. Different abiotic factors like moisture stress, temperature fluctuation, growing medium, nutrient imbalance, plant density and harvesting time cause a disturbance in the metabolic activities of root tissues that produce non-marketable roots. Therefore, this review provides a detail insight on the causes, physiology of these disorders, and the management practices to prevent them to produce commercial quality roots. This comprehensive knowledge will not only help the growers, but it will provide relative information for researchers as well to control these disorders through breeding innovations and biotechnological tools.
Multi-Walled Carbon Nanotubes Improved Development during In Vitro Multiplication of Sugarcane (Saccharum spp.) in a Semi-Automated Bioreactor
Authors: Sorcia-Morales Monserrat , Gómez-Merino Fernando Carlos , Sánchez-Segura Lino , Spinoso-Castillo José Luis , Bello-Bello Jericó Jabín
Published: September 2021

Carbon nanotubes play an important role in plant biotechnology due to their effects on the growth and differentiation of cells, tissues, organs, and whole plants. This study aimed to evaluate the effect of multi-walled carbon nanotubes (MWCNTs) during in vitro multiplication of sugarcane (Saccharum spp.) using a temporary immersion system. Morphological characterization of MWCNTs was carried out under a transmission electron microscope. Different concentrations (0, 50, 100, 200 mg L−1) of MWCNTs were added to Murashige and Skoog liquid culture medium in the multiplication stage. At 30 d of culture, number of shoots per explant, shoot length, number of leaves per shoot, total chlorophyll, dry matter percentage, carbon percentage, and macro- and micronutrient content were evaluated. Results showed an increase in the development of sugarcane shoots at concentrations of 100 and 200 mg L−1 MWCNT. Total chlorophyll content increased at concentrations of 50 and 100 mg L−1 MWCNT, whereas macro- and micronutrient content was variable at the different MWCNT concentrations. Results suggest a hormetic effect, characterized by stimulation at low concentrations. In conclusion, the use of low concentrations of MWCNTs had positive effects on development, total chlorophyll, carbon percentage, and macro- and micronutrient (N, Ca, S, Fe, Cu, Zn and Na) contents during in vitro multiplication of sugarcane and may have a potential use in other species of agricultural interest.
Free Radical Scavenging Activity of Infusions of Different Medicinal Plants for Use in Obstetrics
Authors: Jarco Sylwia , Pilawa Barbara , Ramos Paweł
Published: September 2021

An X-band (9.3 GHz) electron paramagnetic resonance (EPR) spectroscopy was used to examine the free radical scavenging activity of the following infusions, which were nonirradiated and exposed to UVA: root of Asparagus racemosus and herbs of Mitchella repens, Cnicus benedictus L., Galega officinalis L., and Eupatorium cannabinum L. The plant materials for obstetrics applications were chosen for analysis. The aims of these studies were to compare the free radical scavenging ability of the tested infusions and to determine the influence of UVA irradiation of the plant materials on interactions of these infusions with free radicals. Both the magnitude and kinetics of the interactions of the infusions with the model DPPH free radicals were examined. The ability to quench the free radicals for the examined plant infusions increases in the following order: Asparagus racemosus (root) < Mitchella repens (herb) < Cnicus benedictus L. (herb) < Galega officinalis L. (herb) < Eupatorium cannabinum L. (herb). The analyzed infusions differ in the kinetics of the interactions with free radicals. The fastest interactions with free radicals characterize the infusions of Galega officinalis L. herb and Eupatorium cannabinum L. herb. The infusion of Mitchella repens herb interacts with free radicals in the slowest way. UVA radiation reduces the antioxidant interactions of all tested infusions, especially the infusion of Eupatorium cannabinum L. herb, which should be protected against UVA radiation during storage. The weakest decrease of free radical scavenging activity was observed for the infusion of the root of Asparagus racemosus exposed to UVA radiation. UVA radiation affected the speed of the free radical interactions of the infusions, depending on the type of plant materials. EPR spectroscopy is useful to examine the free radical scavenging activity of plant infusions, which is helpful to find effective antioxidants for applications in obstetrics and their optimal storage conditions.
Biochemical Basis for the Time-of-Day Effect on Glufosinate Efficacy against Amaranthus palmeri
Authors: Takano Hudson K. , Dayan Franck E.
Published: September 2021

Glufosinate, a glutamine synthetase (GS) inhibitor, often provides variable weed control depending on environmental conditions such as light, temperature and humidity at the time of application. Midday applications normally provide improved efficacy compared to applications at dawn or dusk. We investigated the biochemical basis for the time-of-day effect on glufosinate efficacy in Amaranthus palmeri. GS1/GS2 gene expression and GS1/GS2 protein abundance were assessed in different parts (young leaves, old leaves, and roots) of plants incubated in the dark compared to those in the light. The turnover of GS total activity was also evaluated overtime following glufosinate treatment at midday compared to dusk application. The results suggest that GS in A. palmeri is less expressed and less abundant in the dark compared to in the light. Midday application of glufosinate under intense light conditions following application provide full control of A. palmeri plants. Consequently, these plants are unable to recover GS activity by de novo protein synthesis. Full activity of GS is required for complete inhibition by the irreversible inhibitor glufosinate. Therefore, glufosinate applications should always be performed in the middle of the day when sunlight is intense, to prevent weed escapes from the herbicide treatment.
Enhancement of Phytosterol and Triterpenoid Production in Plant Hairy Root Cultures—Simultaneous Stimulation or Competition?
Authors: Rogowska Agata , Szakiel Anna
Published: September 2021

Plant in vitro cultures, including hairy roots, can be applied for controlled production of valuable natural products, such as triterpenoids and sterols. These compounds originate from the common precursor squalene. Sterols and triterpenoids distinctly differ in their functions, and the 2,3-oxidosqualene cyclization step is often regarded as a branch point between primary and secondary (more aptly: general and specialized) metabolism. Considering the crucial role of phytosterols as membrane constituents, it has been postulated that unconstrained biosynthesis of triterpenoids can occur when sterol formation is already satisfied, and these compounds are no longer needed for cell growth and division. This hypothesis seems to follow directly the growth-defense trade-off plant dilemma. In this review, we present some examples illustrating the specific interplay between the two divergent pathways for sterol and triterpenoid biosynthesis appearing in root cultures. These studies were significant for revealing the steps of the biosynthetic pathway, understanding the role of particular enzymes, and discovering the possibility of gene regulation. Currently, hairy roots of many plant species can be considered not only as an efficient tool for production of phytochemicals, but also as suitable experimental models for investigations on regulatory mechanisms of plant metabolism.
Elements of 3D Bioprinting in Periodontal Regeneration: Frontiers and Prospects
Authors: Wang Ziyi , Huang Xin
Published: September 2021

Periodontitis is a chronic infectious disease worldwide, caused by the accumulation of bacterial plaque, which can lead to the destruction of periodontal supporting tissue and eventually tooth loss. The goal of periodontal treatment is to remove pathogenic factors and control the periodontal inflammation. However, the complete regeneration of periodontal supporting tissue is still a major challenge according to current technology. Tissue engineering recovers the injured tissue through seed cells, bio-capable scaffold and bioactive factors. Three-D-bioprinting is an emerging technology in regeneration medicine/tissue engineering, because of its high accuracy and high efficiency, providing a new strategy for periodontal regeneration. This article represents the materials of 3D bioprinting in periodontal regeneration from three aspects: oral seed cell, bio-scaffold and bio-active factors.
A Single-Actuated, Cable-Driven, and Self-Contained Robotic Hand Designed for Adaptive Grasps
Authors: Nikafrooz Negin , Leonessa Alexander
Published: September 2021

Developing a dexterous robotic hand that mimics natural human hand movements is challenging due to complicated hand anatomy. Such a practical design should address several requirements, which are often conflicting and force the designer to prioritize the main design characteristics for a given application. Therefore, in the existing designs the requirements are only partially satisfied, leading to complicated and bulky solutions. To address this gap, a novel single-actuated, cable-driven, and self-contained robotic hand is presented in this work. This five-fingered robotic hand supports 19 degrees of freedom (DOFs) and can perform a wide range of precision and power grasps. The external structure of fingers and the thumb is inspired by Pisa/IIT SoftHand, while major modifications are implemented to significantly decrease the number of parts and the effect of friction. The cable configuration is inspired by the tendon structure of the hand anatomy. Furthermore, a novel power transmission system is presented in this work. This mechanism addresses compactness and underactuation, while ensuring proper force distribution through the fingers and the thumb. Moreover, this power transmission system can achieve adaptive grasps of objects with unknown geometries, which significantly simplifies the sensory and control systems. A 3D-printed prototype of the proposed design is fabricated and its base functionality is evaluated through simulations and experiments.
Thermal Imagery Feature Extraction Techniques and the Effects on Machine Learning Models for Smart HVAC Efficiency in Building Energy
Authors: Acquaah Yaa Takyiwaa , Gokaraju Balakrishna , Tesiero Raymond C. , Monty Gregory H.
Published: September 2021

The control of thermostats of a heating, ventilation, and air-conditioning (HVAC) system installed in commercial and residential buildings remains a pertinent problem in building energy efficiency and thermal comfort research. The ability to determine the number of people at a particular time in an area is imperative for energy efficiency in order to condition only occupied regions and thermally deficient regions. In this study of the best features comparison for detecting the number of people in an area, feature extraction techniques including wavelet scattering, wavelet decomposition, grey-level co-occurrence matrix (GLCM) and feature maps convolution neural network (CNN) layers were explored using thermal camera imagery. Specifically, the pretrained CNN networks explored are the deep residual (Resnet-50) and visual geometry group (VGG-16) networks. The discriminating potential of Haar, Daubechies and Symlets wavelet statistics on different distributions of data were investigated. The performance of VGG-16 and ResNet-50 in an end-to-end manner utilizing transfer learning approach was investigated. Experimental results showed the classification and regression trees (CART) model trained on only GLCM and Haar wavelet statistic features, individually achieved accuracies of approximately 80% and 84%, respectively, in the detection problem. Moreover, k-nearest neighbors (KNN) trained on the combined features of GLCM and Haar wavelet statistics achieved an accuracy of approximately 86%. In addition, the performance accuracy of the multi classification support vector machine (SVM) trained on deep features obtained from layers of pretrained ResNet-50 and VGG-16 was between 96% and 97%. Furthermore, ResNet-50 transfer learning outperformed the VGG-16 transfer learning model for occupancy detection using thermal imagery. Overall, the SVM model trained on features extracted from wavelet scattering emerged as the best performing classifier with an accuracy of 100%. A principal component analysis (PCA) on the wavelet scattering features proved that the first twenty (20) principal components achieved a similar accuracy level instead of training on the whole feature set to reduce the execution time. The occupancy detection models can be integrated into HVAC control systems for energy efficiency and security systems, and aid in the distribution of resources to people in an area.
Sustainability of Regional Factors on the Gendered Division of Housework in China
Authors: Guan Chenghua , Zuo Ling
Published: September 2021

In China’s labor market, the traditional patterns of “male breadwinners, female housewives” have been changing noticeably, whereas such patterns remain unchanged in the household production field. This phenomenon greatly affects gender equality and social sustainability. Until now, most of the studies have focused on the attribution of micro-factors (e.g., individual income, education level, and time availability) to the formation of this pattern. However, the effect of macro-region factors (e.g., the regional economic development, population composition, employment, and gender norms) on the distribution of housework have been rarely studied. In this study, the data from the China General Social Survey (2015CGSS) and the China Genuine Progress Indicator Survey (2017CGPiS) of Beijing Normal University were comprehensively analyzed. On that basis, a gender norms index was first constructed to measure regional differences in gender concepts. Moreover, this study, by considering macro-region-varying factors, suggested that the synergetic effect between all of the mentioned factors could significantly impact the distribution of housework, especially in eastern China. Nevertheless, in western China, the effect of male gender norms on the distribution of housework is significantly more serious than that of female gender norms, which inspires the authors of this study to strengthen the male’s family consciousness education. All of the mentioned findings could help formulate region-differentiated policies and strategies to achieve more reasonably and sustainably distributed housework in China.
COVID-19 Vaccine and Social Media in the U.S.: Exploring Emotions and Discussions on Twitter
Authors: Karami Amir , Zhu Michael , Goldschmidt Bailey , Boyajieff Hannah R. , Najafabadi Mahdi M.
Published: September 2021

The understanding of the public response to COVID-19 vaccines is the key success factor to control the COVID-19 pandemic. To understand the public response, there is a need to explore public opinion. Traditional surveys are expensive and time-consuming, address limited health topics, and obtain small-scale data. Twitter can provide a great opportunity to understand public opinion regarding COVID-19 vaccines. The current study proposes an approach using computational and human coding methods to collect and analyze a large number of tweets to provide a wider perspective on the COVID-19 vaccine. This study identifies the sentiment of tweets using a machine learning rule-based approach, discovers major topics, explores temporal trend and compares topics of negative and non-negative tweets using statistical tests, and discloses top topics of tweets having negative and non-negative sentiment. Our findings show that the negative sentiment regarding the COVID-19 vaccine had a decreasing trend between November 2020 and February 2021. We found Twitter users have discussed a wide range of topics from vaccination sites to the 2020 U.S. election between November 2020 and February 2021. The findings show that there was a significant difference between tweets having negative and non-negative sentiment regarding the weight of most topics. Our results also indicate that the negative and non-negative tweets had different topic priorities and focuses. This research illustrates that Twitter data can be used to explore public opinion regarding the COVID-19 vaccine.
Worldwide Vaccination Willingness for COVID-19: A Systematic Review and Meta-Analysis
Authors: Nehal Kimberly R. , Steendam Lieke M. , Campos Ponce Maiza , van der Hoeven Marinka , Smit G. Suzanne A.
Published: September 2021

Countries across the globe are currently experiencing a third or fourth wave of SARS-CoV-2 infections; therefore, the need for effective vaccination campaigns is higher than ever. However, effectiveness of these campaigns in disease reduction is highly dependent on vaccination uptake and coverage in susceptible populations. Therefore, this systematic review and meta-analysis estimated the vaccination intention and identified determinants of willingness and hesitancy. This study updates the existing body of literature on vaccination willingness, and was conducted according to the PRISMA guidelines. PubMed was searched for publications, selecting only studies published between 20 October 2020 and 1 March 2021, in English, with participants aged >16 years of age. The search identified 411 articles, of which 63 surveys were included that accounted for more than 30 countries worldwide. The global COVID-19 vaccination willingness was estimated at 66.01% [95% CI: 60.76–70.89% I2 = 99.4% [99.3%; 99.4%]; τ2 = 0.83]. The vaccination willingness varied within as well as between countries. Age, gender, education, attitudes and perceptions about vaccines were most frequently observed to be significantly associated with vaccine acceptance or refusal.
Plasmodium falciparum Malaria Vaccines and Vaccine Adjuvants
Authors: Bonam Srinivasa Reddy , Rénia Laurent , Tadepalli Ganesh , Bayry Jagadeesh , Kumar Halmuthur Mahabalarao Sampath
Published: September 2021

Malaria—a parasite vector-borne disease—is a global health problem, and Plasmodium falciparum has proven to be the deadliest among Plasmodium spp., which causes malaria in humans. Symptoms of the disease range from mild fever and shivering to hemolytic anemia and neurological dysfunctions. The spread of drug resistance and the absence of effective vaccines has made malaria disease an ever-emerging problem. Although progress has been made in understanding the host response to the parasite, various aspects of its biology in its mammalian host are still unclear. In this context, there is a pressing demand for the development of effective preventive and therapeutic strategies, including new drugs and novel adjuvanted vaccines that elicit protective immunity. The present article provides an overview of the current knowledge of anti-malarial immunity against P. falciparum and different options of vaccine candidates in development. A special emphasis has been made on the mechanism of action of clinically used vaccine adjuvants.
Humoral and Cellular Vaccination Responses against SARS-CoV-2 in Hematopoietic Stem Cell Transplant Recipients
Authors: Lindemann Monika , Klisanin Vesna , Thümmler Laura , Fisenkci Neslinur , Tsachakis-Mück Nikolaos , Ditschkowski Markus , Schwarzkopf Sina , Klump Hannes , Reinhardt Hans Christian , Horn Peter A. , Koldehoff Michael
Published: September 2021

The cellular response to SARS-CoV-2 vaccination and infection in allogeneic hematopoietic stem cell transplant (HSCT) recipients is not yet clear. In the current study, HSCT recipients prior to and post vaccination were tested for SARS-CoV-2-specific humoral and cellular immunity. Antibodies against spike (S) 1 were assessed by Anti-SARS-CoV-2 IgG ELISA (Euroimmun). Cellular immunity was analyzed by an in house interferon-gamma ELISpot and T-SPOT.COVID (Oxford Immunotec), using altogether seven SARS-CoV-2-specific antigens. In 117 HSCT patients vaccinated twice, SARS-CoV-2 IgG antibodies were significantly higher than in HSCT controls pre vaccination (p < 0.0001). After the second vaccination, we observed a median antibody ratio of 4.7 and 68% positive results, whereas 35 healthy controls reached a median ratio of 9.0 and 100% positivity. ELISpot responses in patients were significantly (p < 0.001) reduced to ≤33% of the controls. After the second vaccination, female HSCT patients and female healthy controls showed significantly higher antibody responses than males (6.0 vs. 2.1 and 9.2 vs. 8.2, respectively; p < 0.05). Cellular immunity was diminished in patients irrespective of sex. In conclusion, especially male HSCT recipients showed impaired antibody responses after SARS-CoV-2 vaccination. Changing the vaccine schedule or composition could help increase vaccine responses.
Association between Adult Vaccine Hesitancy and Parental Acceptance of Childhood COVID-19 Vaccines: A Web-Based Survey in a Northwestern Region in China
Authors: A Kezhong , Lu Xinyue , Wang Jing , Hu Linjie , Li Bingzhe , Lu Yihan
Published: September 2021

China has initiated the COVID-19 vaccination for children aged 15–17 years since late July 2020. This study aimed to determine the association between adult vaccine hesitancy and parental acceptance of childhood COVID-19 vaccines in a multi-ethnicity area of northwestern China. A web-based investigation was performed with a convenience sampling strategy to recruit the parents aged 20–49 years. In a total of 13,451 valid respondents, 66.1% had received the COVID-19 vaccination, 26.6% were intent to receive, while 7.3% were not intent, with an increasing vaccine hesitancy (p < 0.001). Moreover, vaccination uptake of four common vaccines in their children remained low (29.0% for influenza vaccine, 17.9% for pneumonia vaccine, 10.9% for rotavirus vaccine, 8.0% for Enterovirus-71 vaccine), while overall parental acceptance of childhood COVID-19 vaccines was 50.0% (32.7% for those aged 0–5, 46.6% for 6–10, 73.3% for 11–18; p < 0.001). Vaccination uptake of these four vaccines and parental acceptance of childhood COVID-19 vaccine were negatively associated with adult vaccine hesitancy. In addition, respondents mostly preferred childhood COVID-19 vaccines with weak mild common adverse events (β = 1.993) and no severe adverse events (β = 1.731), demonstrating a positive association with adult vaccine hesitancy. Thus, it warrants specific countermeasures to reduce adult vaccine hesitancy and improve strategies for childhood vaccination.
Passagens em rede imaginadas: as imagens do comércio do centro de Juiz de Fora (Brasil)
Authors:   , Grossi Virgínia Campos
Published: September 2021

A pesquisa aborda o tema do imaginário urbano e das passagens em rede do centro de Juiz de Fora (Brasil), mais especificamente, as imagens das passagens em rede produzidas por seus comerciantes na contemporaneidade. Entende-se por “passagens em rede” como o conjunto de caminhos para os pedestres conformados pelas galerias e pelos calçadões, que, junto ao comércio, promovem diversidade, vitalidade e contribuem para a manutenção do fenômeno da centralidade na cidade. A morfologia peculiar das passagens em rede e a forte presença do comércio criam uma espécie de “shopping a céu aberto”, que, junto à localização central e à presença de arquiteturas e elementos urbanos históricos, reforçam o antigo centro de Juiz de Fora como um lugar vivo e simbólico para a cidade na contemporaneidade. Dadas a grande vitalidade e importância simbólica das passagens em rede na contemporaneidade e a relevância e a interferência do ambiente construído sob as imagens produzidas pelo imaginário urbano, a pesquisa debruçou-se sobre a seguinte questão: quais são as imagens das passagens em rede presentes no imaginário dos comerciantes do centro de Juiz de Fora? O objetivo geral da pesquisa consistiu em compreender as passagens em rede na contemporaneidade à luz do imaginário urbano de seus comerciantes e da revisão de literatura. Assim, por meio da revisão de literatura, a pesquisadora selecionou quatro categorias existentes no contexto urbano das passagens em rede para investigar no imaginário urbano dos comerciantes: (i) shopping a céu aberto; (ii) morfologia labiríntica; (iii) centralidade, vitalidade e sociabilidade; (iv) lugar simbólico: memória, cultura e identidade. A metodologia baseia-se, de forma sucinta, em três etapas: (i) revisão de literatura sobre o imaginário no campo das ciências sociais e sobre as passagens em rede do centro de Juiz de Fora; (ii) pesquisa de campo através do “olhar da pesquisadora” e de “outros olhares” (ou olhares dos comerciantes); (iii) análises e discussão dos resultados da pesquisa de campo à luz da revisão de literatura. Como resultado, de forma geral, foi observado que as imagens das passagens em rede alimentadas pelo imaginário urbano dos comerciantes desse lugar expressam características presentes nas quatro categorias de análises, as quais são reforçadas pelos teóricos da revisão de literatura. A imagem das passagens em rede mais enfatizada pelos comerciantes foi a de um shopping a céu aberto com vida pulsante e que expressa cultura e identidade por meio do comércio e das galerias na contemporaneidade.
Maternagem e cuidado como desejo de democracia: educação infantil em perspectiva feminista
Authors:   , Ramos Maria Rita Neves
Published: September 2021

Este trabalho tem como objetivo conhecer as relações de maternagem na Educação Infantil a partir do diálogo e reflexão acerca de como tais relações concorrem para assegurar o efetivo exercício dos direitos das mulheres e direito das crianças. Para cumprir o objetivo da pesquisa, estabelecemos como objeto de análise as concepções e práticas escolares relativas à educação das crianças, sobretudo na perspectiva do cuidado. Nesse sentido, cuidado é conceito assumido na pesquisa associado ao debate sobre maternagem, a partir da concepção da manutenção do criar e educar desenvolvida por Dagmar Meyer (2005). A partir das análises e reflexões propostas, a presente pesquisa adota o pressuposto da corresponsabilidade da Educação, já prevista na legislação brasileira, como no Estatuto da Criança e do Adolescente (BRASIL, 1990) e na própria Constituição Federal (BRASIL, 1988). Sendo assim, o foco do estudo se volta ao aparato institucional, social e familiar necessário à educação das crianças, posto que a abordagem adotada percebe a creche como tendo impacto direto nas variadas searas das vidas das mulheres e crianças, sendo esses dois grupos populacionais ainda passíveis de serem minorias sociais, ainda que não sejam minorias numéricas. Diante dessa conjuntura e da necessidade de repensarmos as condições de reconhecimento social de mulheres e crianças, a pesquisa adota como campo a rede de ensino municipal de Juiz de Fora (MG) e busca atingir o objetivo da pesquisa a partir do diálogo sobre como os feminismos exercem (ou não) influência nas práticas educadoras da Educação Infantil, de modo a assegurar que este nível de ensino seja seara de direitos das populações que recorrem à creche como equipamento de Estado. Foram realizados encontros formativos com as professoras da creche e as discussões foram fundamentadas em textos e materiais audiovisuais, na perspectiva de diálogo sobre a Educação Infantil e a garantia e manutenção de direitos das mulheres e direitos das crianças. As reflexões produzidas nos encontros formativos indicam que a Educação Infantil é um contexto potente, porém desafiador, ao debate da maternagem.
Reconhecimento de padrões moleculares, clínicos e imunológicos para criação de algoritmo da suscetibilidade e evolução clínica da Hanseníase baseado em inteligência artificial.
Authors:   , Souza Márcio Luís Moreira de
Published: September 2021

A hanseníase é uma doença de transmissão ativa e caracteriza-se por heterogeneidade de manifestações clínicas - do pólo tuberculóide (TT) ao virchowiano (LL) - as quais estão correlacionadas com a resposta imune mediada por células do hospedeiro contra o bacilo causador Mycobacterium leprae. A resposta imune do Tipo Th-1 nos pacientes com a forma clínica TT ou paucibacilar é eficaz em limitar a doença clínica. Por outro lado, a forma clínica LL ou multibacilar caracteriza-se por baixa imunidade mediada por células com uma resposta humoral pela ativação de células Th-2. O papel dos fatores genéticos do hospedeiro no desenvolvimento da hanseníase tem sido bem estabelecido através de indicadores epidemiológicos e estudos genéticos do hospedeiro na susceptibilidade à hanseníase. Os resultados de análises ampla do genoma (ligação e associação) e estudos de genes candidatos sugerem um controle genético independente tanto da susceptibilidade à hanseníase per se como do desenvolvimento das diferentes formas clínicas. Nesse trabalho, buscamos avaliar os níveis de citocinas (IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ e IL-17) e quimiocinas (CXCL8/IL-8, CCL5/RANTES, CXCL9/MIG, CCL2/MCP-1 e CXCL10/IP-10), genotipar polimorfismos de um único nucleotídeo (SNP) dos genes TLR4 (rs4986790, rs2149356, rs1927914 e rs2737190), IL-10 (rs1554286, rs3024490, rs1800872 e rs1800871), TLR1 (rs4833095),TLR2 (rs3804099) e SLC11A1 (rs17235416) de resposta imunológica dos pacientes e dos seus contatos intradomiciliares e associá-los aos dados clínicos da hanseníase. Foi também implementado um modelo baseado em Random Forest, que nos permitiu, com cerca de 97% de acurácia, predizer a evolução clínica dos contatos domiciliares pelo reconhecimento do padrão de suas variáveis clínicas e imunológicas. Além disso, dentre outros achados, foi evidenciado um padrão diferencial das quimiocinas (em especial IL-8 e RANTES) na cultura de células estimuladas pelo M. leprae quando comparada a cultura sem estímulo. Foi verificada uma chance de adoecimento 2,3 vezes maior nos indivíduos portadores do alelo G nas variantes rs1927914 ou rs2737190 do gene TLR4.
Сравнение глобальных моделей гравитационного поля на территории Магаданской области
Authors:   North-East Interdisciplinary Scientific Research Institute n. a. N. A. Shilo, FEB RAS, Magadan, Khasanov I. M. , Muravyev L. A. ,   Institute of Geophysics UB RAS, Yekaterinburg
Published: September 2021

The global databases of gravity anomalies, currently available to researchers, provide a new informative tool for constructing density models of the deep structure of the earth's crust for individual regions. Currently, there are six models of gravitational anomalies, presented as a series of spherical harmonics up to 2190 degrees, which corresponds to about 10 km on the earth's surface. Different methods of processing terrestrial, marine, aerial, and satellite gravimetric data, available to their authors, determine the differences between these models, both on a global scale and within specific regions. We have performed a comparison of the EGM2008, GECO, EIGEN-6C4, and WGM2012 models with the Gravimag database on the Magadan Oblast territory. The comparison showed that free air anomalies for the EGM2008, GECO, EIGEN-6C4, and WGM2012 models in the selected area almost coincide. Bouguer anomalies of the WGM2012 model can be used in regional density modeling for adjacent regions where there are no conventional ground gravity data; however, within Magadan Oblast the Gravimag database has the best data quality.
MEMPREDIKSI FINANCIAL DISTRESS PADA PERUSAHAAN SEKTOR TEKSTIL DAN GARMENT YANG TERDAFTAR DI BEI
Authors: Hendriani Maria , Saleh Dean Subhan , Kartika Rika
Published: September 2021

The prospect of the textile and garment sector in Indonesia is predicted to continue to decline since the last few years. The purpose of this study is to predict financial difficulties in textile and garment sector companies listed on the Indonesia Stock Exchange in 2016-2018. The independent variables used in this study are Current Ratio, Enterprise Risk Management, and Labor Costs. The Financial Distress model used in this study is the Altman Z score. This research data was obtained from the Indonesia Stock Exchange for the period 2016-2018. The sample used in this study were 12 textile and garment sector companies with saturated sampling method. The analysis technique used in this research is panel data regression. The results showed that the Current Ratio had a positive and significant effect on predicting Financial Distress, the proportion of Enterprise Risk Management had no significant effect on predicting Financial Distress, and Labor Costs had a significant negative effect on predicting Financial Distress.
PROCEDURE FOR ESTIMATING THE BOUNDARY DISTANCE OF SHORE RADIO STATIONS IN VHF RANGE FOR THE SHORE-TO-SHIP DIRECTION
Authors: ПРОЦЕНКО М.Б. , ГРОМОЗДИН В.В. , КОЗУБ М.С.
Published: September 2021

Сформулирована и детализирована методика оценивания граничной дальности береговых ОВЧ радиостанций в направлении Берег-Судно, которая основана на зависимостях напряженности поля, полученных эмпирическим путем. Определены численные значения граничной дальности ОВЧ радиосвязи применительно к типовому судовому радиооборудованию и шумовой обстановке вблизи судовой антенны. Проведена оценка максимальных допусков определения граничной дальности ОВЧ радиосвязи.

The procedure for estimating the boundary distance of the shore VHF radio stations in the shore-to-ship direction, which is based on the dependences of the electromagnetic field strength obtained empirically, has been formulated and detailed. Numerical values of the boundary distance of VHF radio communication in relation to typical ship radio equipment and the noise environment near the ship's antenna are determined. The estimation of the maximum tolerances for determining the boundary distance of VHF radio communication is carried out.
Musicogramas dinámicos: les toreadors (George Bizet)
Authors: Galera Núñez María del Mar , de Frutos Domínguez Rocío
Published: September 2021

En este musicograma se presenta uno de los temas de la Suite nº1 de Carmen de George Bizet. En concreto: “Les toreadors”. Esta pieza orquestal tiene una forma musical compuesta por tres secciones diferentes que contrastan entre sí. Su forma musical responde al esquema: A A B C C´ A coda. La parte A es el tema principal con el que empieza y termina la obra y tiene un marcado carácter abierto y triunfal en la que se implica a la orquesta al completo y en donde la percusión tiene un papel muy marcado. A esta sección A le sigue una sección B que tiene un sentido de puente debido a las continuas progresiones en tensión que nos mueven hasta la sección C. La nueva sección C contrasta con todo lo anterior por ser una parte más suave y melodiosa a cargo de las cuerdas. Esa parte se vuelve a repetir una segunda vez en un volumen más elevado y con un final diferente que da paso de nuevo a la reposición de la sección A. El final se adorna con una pequeña coda que determina el final de la pieza.

En el proyecto Musicogramas dinámicos las alumnas y alumnos del grado de Educación Infantil dentro de la asignatura de Formación Musical, generaron musicogramas de determinadas piezas instrumentales. Se han seleccionado piezas que se consideran adecuadas para la escucha activa en la etapa de infantil y que por tanto, no superan los tres minutos de duración. Los diferentes recursos elaborados contienen animaciones que representan la forma musical de la pieza y algunas de sus características musicales más destacadas.
A UNIQUE DISORDER OF THE STERNUM : HONEYCOMB STERNA
Authors: Kumar Santosh , Prasad Makardhaj
Published: September 2021

This article describes an uncommon example of a human sternal developmental anomaly in an
anatomical specimen from the Department of Anatomy at Shahid Nirmal Mahto Medical College
Dhanbad. The non-fusion of lateral ossication centres in the sternebrae caused the uncommonly recognized developmental
anomaly, which results in a honeycomb-like appearance of the mesosternum. Sternal deciencies are normally under
diagnosed in the clinical literature due to the fact that many instances are asymptomatic. As a result, there is a gap in our
modern understanding of the development and anatomical variations of the sternum. Although in the past, large-scale CT
investigations have been conducted to explore the incidence of sternal developmental anomalies. A very rare work has been
reported on sternal malformations. Most of the sternal abnormalities are clinically insignicant; a lack of awareness of these
variants can lead to interpretation of radiological and pathological evidence. Hence, anatomical variants are asymptomatic
which is vital in nature.
ATTITUDE TOWARDS PSYCHIATRY AMONG NON-PSYCHIATRIC POSTGRADUATES IN A TERTIARY CARE TEACHING HOSPITAL
Authors: Singh Swati , Pradeep Arun Narayan , Dinakaran Vadivambal , Saravanan Arul , Thirunavukarasu M.
Published: September 2021

It is a universal phenomenon that the stigma attached to mental illness and mentally ill is a major barrier
in providing mental health services. Among doctors, the stigmatisation can further lead to decline in
treating mental illness and compromises in patient care. Mental illnesses go unnoticed and unattended to most of the time.
AIM-To study the attitude towards mental illness and psychiatry in non-psychiatric postgraduates in a tertiary care hospital.
Materials and methods- This is a “Cross - sectional study” that was carried out among non-psychiatric post graduates in a
tertiary care hospital using validated questionnaire among all non-psychiatric postgraduates
Results- Out of 235 non-psychiatric postgraduate's only 200 postgraduates have lled questionnaire. Out of which 88 were
male and 112 were females and 168 were from the clinical branch and 32 were from the non-clinical branch. Data analyse was
by using SPSS. Total scores were high on MICA -4 (56.99±9.59) which represent negative attitude towards psychiatry. The
majority of postgraduates have shown little interest in psychiatry in their MBBS programme and believe that functioning in a
psychiatric setup is not respectful and have been reluctant to disclose their mental illness in front of friends and colleagues. On
otherhand, they accepted that mental illness could be a treated and that people with psychiatric illness must have the right to
live with dignity and not to be mistreated.
Conclusion- The present study shows the negative perception of non-psychiatric medical post graduates. It shows the urgent
need to revise the curriculum and correct the negative attitudes of non-psychiatric post graduates towards mental illness and to
instil and impart the importance of mental health among students right from undergraduate days. This would help in providing
people with mental illness a holistic care for their problems.
A STUDY ON PREVALENCE OF POST-PARTUM DEPRESSION IN TERTIARY CARE HOSPITAL OF NORTH INDIA.
Authors: Johri Nidhi , Kumar Priti
Published: September 2021

Background: Depression is the most common complication postpartum affecting 10%–15% of women,
contributing greatly to maternal mortality and morbidity, but the care availed is very low among the
women who suffer. Aim and Objectives: The current study aimed to study the prevalence and associated risk factors of
postpartum depression among recently delivered women in a tertiary care hospital of North India. Material and Methods: This
was a hospital based cross-sectional study done between May 2019 and January 2020. All women in the study area who had a
pregnancy outcome during the past 6 months and have completed 42 days since their last delivery were included in the study.
The data on postpartum depression were collected using the Edinburgh Postnatal Depression Scale (EPDS). Results: There
were 300 postpartum women in the study area who participated in the study. Mean age of the study participants was 24.5 years.
The deliveries were Institutional in 98% of women. The prevalence of depression among the study women (an EPDS score of 10
and above) was 10%. Among women with depression, a history of depression before the last delivery was given by 40% of
women. Only 7.5% of women had sought some form of health care for their problem. Conclusion: The study shows that the
prevalence of depression among postpartum women is quite high and the health seeking for depression is very low. Health
professionals and workers have to be trained to raise awareness, detect, and treat depression among postpartum women
promptly
EFFECT OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS DURING THORACOLUMBAR SPINE SURGERY
Authors: KS Santhi , JP Smrithi , Cheeran Susan T
Published: September 2021

BACKGROUND: Spine surgeries are usually associated with excessive blood loss, which increases
morbidity and mortality due to hemodynamic instability and subsequent blood transfusions. Tranexamic
acid (TXA), an antibrinolytic drug, inhibits the activation of plasminogen, is found to be useful in reducing blood loss.
METHODOLOGY: A prospective observational study conducted in Government Medical College, Kottayam for a period of
twelve months, randomly assigned forty-eight adult patients (ASA I or II) undergoing thoracolumbar spine surgery into two
groups, who received either a bolus of 10 mg/kg IV TXA after induction followed by an infusion of 1 mg/kg/h of TXA up to closure
of skin, or an equivalent volume of normal saline. Blood investigations, surgical parameters, perioperative blood loss and
blood transfusions were assessed.
RESULTS: Both groups in the study were comparable with respect to demographic variables, baseline laboratory indices and
surgical parameters. The mean perioperative blood loss was 44% less (P<0.05) and blood transfusion requirements were 71%
reduced (P<0.05) in patients who received TXA. Mean surgical duration as well as postoperative hemoglobin drop was
signicantly reduced in TXA group compared to Normal Saline group (NS).
CONCLUSION: Tranexamic acid reduces perioperative blood loss and blood transfusion.
SCREENING FOR DRY EYE IN TYPE II DIABETIC PATIENTS IN A TERITIARY EYE CARE HOSPITAL
Authors: Meenakshi Vepa , Aparna Maridi , v Tammana
Published: September 2021

AIM: To screen for dry eye among type 2 diabetic patients ,determine the prevalence and correlate with
blood sugar levels.
METHODS: 100 patients who were diagnosed cases of type 2 diabetes were included in the study .Detailed history regarding
ocular symptoms, diabetes and its duration was taken. A thorough ocular examination using Slit lamp bio microscopy was
done and visual acuity tested with Snellen's chart.Tear lm status evaluated by Schirmer's I test, Tear lm break up
time(TBUT),Tear meniscus height. Two or all of the above performed tests was positive in a given patient, the patient was
deemed to be suffering from dry eye.
RESULTS:Out of 100 patients, males were 48 and females were 52. 39 patients were found to show positive screening tests for
dry eye.38% (out of 39 patients) had major symptom of foreign body sensation. 23 out of 39 patients were females. 14 out of 39
patients were in age group 51 to 60 years.Most of the diabetics with dry eye had duration of disease 5 to 10 years .39 patients
had Tear Break Up time <10 sec, 25 patients had Tear Meniscus Height <0.25mm and 36 patients had Schirmers I
test<10mm.Diabetics with dry eyes had average RBS of 179.63+57.28 and PPBS of 247.75+88.39 mg/dl. These values were
more when compared to diabetics with no dry eye.
CONCLUSION: Early ocular examination in Diabetic patients and good glycemic control should be done considering
increased incidence of dry eyes.This should be an integral part of the assessment of diabetic eye disease so as to improve the
patient's comfort and to prevent or minimize further structural damage to the ocular surface.
A COMPARATIVE STUDY OF FUNCTIONAL AND RADIOLOGICAL OUTCOME OF HIGH ENERGY PROXIMAL TIBIA FRACTURE USING ILLIZAROV EXTERNAL FIXATOR VS HYBRID EXTERNAL FIXATOR
Authors: Shrimal Aditya , Bhati Mahesh , Choudhary Avinash , Choudhary Pradeep , Chohan Jayesh
Published: September 2021

Background: In High energy proximal tibia fracture aim is to achieve adequate reduction and stability
without signicantly compromising the soft tissue integrity and vascularity . External xator minimizes
soft tissue dissection and minimize other complications.
Method: 60 patients' high energy proximal tibia fracture with cases were considered in the study. 30 patients were treated with
Ilizarov external xator and 30 patients were treated with hybrid external xator. Results were analyzed both clinically and
radiologically using Johner and Wruh's criteria.
Results: Mean time of union was 22 week in ilizarov xator group and 34 week in hybrid xator group. Pin tract infection
occured in 6 patient (20%) in ilizarov xator group and 4 patient in hybrid xator group. Joint stiffness occured in 3 Patient (10 %)
in ilizarov group and 10 patient in hybrid xator group.Shortning occured in 2 patient (6.6 %) in ilizarov xator group and 2
patient in hybrid xator group. Overal results in ilizarov group were excellent in 23 patient (76.7%), good in 5 patient (16.67%) ,
fair in 2 patient (6.67%) while in hybrid group excellent in 16 patient( 53.33%),good in 10 patient(33.33%),fair in
4(13.33%)patient.
Conclusion: External xators are excellent modalities in treatment of high energy proximal tibia fracture with ilizarov method
has advantage of early mobilization and early union but require long operative time and bulky framework on other hand hybrid
xator has simpler construct ,lesser operative time but has lesser stability , longer union time and longer immobilization time.