bluuebunny/crossref_metadata_2025 huggingface dataset:
Ảnh hưởng của truyền thông nội bộ minh bạch đến nhận diện tổ chức thông qua vai trò ủng hộ của nhân viên
Authors: Hòa Thị Tươi , Trịnh Thị Nhuần
Published: August 2024

Nghiên cứu này đề cập tới ảnh hưởng của truyền thông nội bộ minh bạch đến nhận diện tổ chức và xem xét tác động trung gian của yếu tố sự ủng hộ của nhân viên. Dữ liệu khảo sát được thu thập từ 301 nhân viên trẻ độ tuổi 18 - 34 tại các doanh nghiệp vừa và nhỏ trên địa bàn Hà Nội. Kết quả phân tích PLS-SEM chỉ ra một số phát hiện mới gồm: tính minh bạch tham gia và tính minh bạch có trách nhiệm ảnh hưởng tích cực đến nhận diện tổ chức, trong khi tính minh bạch thông tin không có ảnh hưởng. Sự ủng hộ của nhân viên ảnh hưởng tích cực đến nhận diện tổ chức và đóng vai trò trung gian trong mối quan hệ giữa cả ba khía cạnh của truyền thông nội bộ minh bạch đến nhận diện tổ chức. Dựa trên kết quả nghiên cứu, một số khuyến nghị được nêu ra dành cho hoạt động truyền thông nội bộ tại doanh nghiệp để gia tăng sự ủng hộ của nhân viên và nhận diện tổ chức.
An Example of Using Advanced Excel Applications Within the Scope of Financial Mathematics Calculations: Modelling of Calculations Related to Annuities in Microsoft Excel Program
Authors: Sayiner Mehmet Anıl
Published: August 2024

Financial mathematics applications, form the mathematical basis for rational financial decisions within the scope of financial management. Carrying out financial management in line with the scientific rules is of vital importance for businesses to sustain their existence and carry out their activities effectively and efficiently. In this context, the ability to carry out financial management rationally is only based on the correct determination of the mathematical datas (etc. time value of money) that forms the basis for decisions. The use of technology in this area is very important and technology level in this area has evolved from financial calculators to computer programs and MS. Excel program is perhaps the most important application tool in this field according to its mathematical calculation capacity and capability. In this regard, the study reveals how to perform complex calculations regarding the present and future values of different annuity types in Excel. The calculation of all variables related to annuity calculations and the mathematical relationships between variables are discussed separately according to different annuity types is examined with a model which developed in Excel program within the scope of the purpose of the study. The study will provide guidance to academics related to the field and professionals working in the field of financial management by combining theoretical knowledge and practical applications.
The Size Effect Anomaly in the Indian Stock Market
Authors: Patel Jayen B.
Published: August 2024

The size effect in stock market implies that small firm stocks generate higher risk-adjusted returns from that of large firm stocks. We did not find a size effect in the Indian stock market for the period of October 2005 to September 2023. We also examined the prevalence of size effect separately by calendar months. Small firm stocks generated significantly higher returns from than of large firms in April and December. Alternately, we did not find a size effect during January, November-December and March to May. We conclude only April and December months’ exhibit a size effect in the Indian stock market.
Bioactive and Medicinal Potential of Edible Flowers
Authors:   Department of Eastern Medicine, Superior University, Lahore, Pakistan, Marium Ahsan , Muhammad Akram ,   Department of Eastern Medicine, Government College University, Faisalabad, Pakistan, Umme Laia ,   Department of Eastern Medicine, Government College University, Faisalabad, Pakistan, Rangasamy Surendar ,   Department of Community Medicine, Sri Venkateshwaraa Medical College Hospital and Research Centre (SVMCHandRC) Puducherry, India, Francisco Garcia-Sierra ,   Department of Cell Biology, Center of Research and Advanced Studies of the National Polytechnical Institute, Mexico City,, Md. Al Hasibuzzaman ,   Department of Nutrition and Food Science, University of Dhaka, Dhaka 1000, Bangladesh, Fethi Ahmet Ozdemir ,   Department of Molecular Biology and Genetics, Faculty of Science and Art, Bingol University, Bingol, 1200, Turkey, Gaweł Sołowski ,   Department of Molecular Biology and Genetics, Faculty of Science and Art, Bingol University, Bingol, 1200, Turkey, Fitria Najmiatul ,   Department of Pharmacology and Clinical Pharmacy, Universitas Andalas, Indonesia, Marcos Altable ,   Department of Neurology, Neuroceuta, (Virgen de Africa Clinic), Spain, Mohamed M Hassan ,   Department of Biology, College of Science, Taif University, Taif, Saudi Arabia, Sfera Adonis ,   Department of Psychiatry, Patton State Hospital, USA
Published: August 2024

From the previous decades edible flowers are effectively used in the treatment of various ailments. These edible flowers also used in salads, sauce, beverages and many more. In the composition of edible flowers lipid content, carotenoids, vitamin E, fatty acid, linoleic acid, alpha linolenic acid, xanthophylls, alpha tocopherol, lutein, zeaxanthin and many more chemical components presents. These chemical component shows various activities like anti-cancer, anti-inflammatory, anti-oxidant etc
Is Botulinum Toxin Type A Safe for Gummy Smile Treatment in Bronchial Asthma Patients? A Case Report
Authors:   Postgraduate Dental Student, Periodontology and Oral Radiology Department, Faculty of Dentistry, Sana'a University, Yemen, Manal Ahmed Abdullah , Al-kholani Abdulwahab Ismail ,   Dean, Head of Restorative and Esthetic Dentistry, Faculty of Dentistry 21 September University, Yemen
Published: August 2024

Background and Aim: The increasing demand for aesthetic enhancements has led to the widespread use of Botox for various facial concerns, including gummy smiles. While its efficacy in treating gummy smiles is established, the safety profile of Botox in patients with underlying medical conditions, such as asthma, remains relatively unexplored. This case report presents a patient with asthma who underwent Botox treatment to correct excessive gingival display. The study aims to demonstrate the potential of Botox for aesthetic improvement in this patient population while emphasizing the need for further research to assess its safety profile. Results: A two-week Botox treatment course successfully eliminated the patient's gummy smile without inducing any asthma-related complications or adverse effects. Conclusion: Although this case suggests the potential of Botox for treating gummy smiles in patients with asthma, it is essential to conduct larger studies to establish its safety and efficacy. A comprehensive medical evaluation is crucial before considering Botox treatment for individuals with underlying health conditions.
Prospects and Challenges for Biodiversity in the Anthropogenic-Induced Cold Arid Landscape of Ladakh, India
Authors:   Principal Scientist, Regional Research Station, ICAR - Central Arid Zone Research Institute (CAZRI), The U.T. of Ladakh, India, Gaur Mahesh Kumar , Goyal R.K. ,   Principal Scientist, Regional Research Station, ICAR - Central Arid Zone Research Institute (CAZRI), The U.T. of Ladakh, India, Kanwar M S ,   Principal Scientist & Head, Regional Research Station, ICAR - Central Arid Zone Research Institute (CAZRI), The U.T. of Ladakh, India, Singh Neelratan ,   Senior Scientist, CSIR - Central Institute of Mining & Fuel Research, Nagpur, MH, India, Choudhary Vipin ,   Principal Scientist, ICAR-Central Arid Zone Research Institute, Jodhpur, India, Chichaghare Akash ,   Scientist, Regional Research Station, ICAR - Central Arid Zone Research Institute (CAZRI), The U.T. of Ladakh, India
Published: August 2024

Ladakh, a high-altitude cold arid region, exhibits conspicuous signs of climate change across its vast landscape. The unique biodiversity of Ladakh faces various challenges due to both exponential anthropogenic activities and the significant threat of climate change to the region's environmental landscape and physiographical variations. The region's unique topography, from high-altitude deserts to soaring Himalayan mountains, makes it a biodiversity hotspot. However, biodiversity is under threat from climate change, infrastructure development, the upward movement of invasive species, and water scarcity due to glacial retreat. There is enough potential to combine traditional ecological knowledge with modern conservation strategies. Climate change, with rising temperatures and glacial retreat, poses a significant threat to Ladakh's biodiversity, particularly that of alpine flora and fauna. Infrastructure development, including roads and hydropower projects, can fragment habitats and dislocate wildlife corridors, leading to reduced genetic diversity. Long-term field observations form the basis for an indepth exploration of prospects and potential threats to the biodiversity of Ladakh's cold arid zone, emphasizing the role of anthropogenic factors in this study.
The Role of the Structure of Matter in its Dynamics and Evolution
Authors:   IETP Al-Farabi Kazakh National University, Almaty, Kazakhstan, Mikhailovich Somsikov Vyacheslav
Published: August 2024

The article is devoted to the study of the role of the structure of the body in its dynamics and evolution. A system of potentially interacting material points was used as a body model. To study the role of body structures, the equation of motion of the system was used. It is shown how it is derived from the condition of invariance of the total energy of the system. This equation takes into account that the work of external forces goes not only to change the energy of motion of the system, but also to change its internal energy. As a result, it was found that taking into account the structural nature of bodies opens up the possibility of describing the processes of their evolution within the framework of the fundamental laws of physics. Based on the condition of infinite divisibility of matter, which follows from the equation of motion of the system, the general principles of organizing the structures of matter at all its hierarchical levels are considered. Examples are given that demonstrate the importance of taking into account the role of the structure of bodies for the development of physics.
A Consistent, Exhaustive Taxonomy of Inventive Activities
Authors:   CNR - IRCrES, Roma, Italy., de Marchi Mario
Published: August 2024

A classification of scientific and technological activities is put forth here, based on taxonomy of Inventive Activities' features. In the end, a description of Research & Innovation ensues that is consistent and more complete than current ones. Then, the gauging of R & I activities may result more meaningful and precise.
Successful Venoarterial Extracorporeal Membrane Oxygenation Treatment in a Pregnant Woman with Amniotic Fluid Embolism
Authors:   Department of Obstetrics and Gynecology, Eulji University School of Medicine, Daejeon, South Korea, Kwan Young Oh , Choi Jinho ,   Department of Cardiologic Surgery, Eulji University School of Medicine, Daejeon, South Korea, Jung Kangjae ,   Department of Rehabilitation Medicine, Eulji University School of Medicine, Daejeon, South Korea, Jung Chang Young ,   Department of Anesthesia, Eulji University School of Medicine, Daejeon, South Korea, Yang Jung Bo ,   Department of Obstetrics and Gynecology, Eulji University School of Medicine, Daejeon, South Korea, Lim Chul Kwon ,   Department of Obstetrics and Gynecology, Eulji University School of Medicine, Daejeon, South Korea, Yang Yun Seok ,   Department of Obstetrics and Gynecology, Eulji University School of Medicine, Daejeon, South Korea
Published: August 2024

Amniotic fluid embolism (AFE) is a rare, but catastrophic, obstetric complication with a high mortality rate. Moreover, >50% of maternal deaths occur within 1 h of symptom development. Further, it involves a high perinatal mortality rate, with 50% of affected neonates presenting neurological impairments. AFE is characterized by cardiovascular collapse, respiratory failure, and coagulopathy, followed by encephalopathy, multi-organ failure, and fetal distress. Therefore, its treatment strategy includes cardiopulmonary support, massive transfusion, and early cesarean section. However, venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been used in cases with rapid progression of cardiac dysfunction, which has significantly decreased the maternal mortality rate. Therefore, VA-ECMO has been accepted as a useful treatment method for patients with AFE, including cardiac dysfunction. This article describes a case in which a patient with AFE was successfully treated with VA-ECMO and presents a literature review.
Vitiligo Associated With Sarcoidosis: Case Based Review
Authors:   Resident, Department of Immunology, Aziz Sancar Institute of Experimental Medicine, İstanbul University, Istanbul, Turkey, Yanardag Emre , Tetikkurt Cuneyt ,   Professor, M.D, Department of Pulmonary Diseases, Istanbul-Cerrahpasa University, Istanbul, Turkey, Bilir Muammar ,   Professor, M.D, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul-Cerrahpasa University, Istanbul, Turkey, Yanardag Halil ,   Professor, M.D, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul-Cerrahpasa University, Istanbul, Turkey, Kimyon Ugur ,   Professor, M.D, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul-Cerrahpasa University, Istanbul, Turkey
Published: August 2024

Sarcoidosis is characterized by non-caseating granulomatous inflammation that predominantly affects the lungs. Cutaneous involvement occurs in 20 to 35 percent of the patients and may emerge as the initial manifestation of the disease. Erythema nodosum and lupus pernio are the specific skin manifestations of cutaneous sarcoidosis. Many different skin lesions including hypopigmentation or hyperpigmentation that mimic other primary skin and systemic diseases may occur in sarcoidosis patients. Cutaneous involvement always poses a diagnostic dilemma in all patients with or without a previous sarcoidosis diagnosis. In this review, we present two sarcoidosis patients who subsequently developed vitiligo. The main aim is to discuss the underlying pathologic mechanisms of sarcoidosis associated with vitiligo and to define the potential relationship between these two autoimmune disorders. The second target is to specify a diagnostic pathway in sarcoidosis patients associated with skin involvement in the light of the current literature data.
Systematic Review on Pathology and Drug Efficacy Clinical Trials (1973-2023) for Cognitive Impairment and Alzheimer’s Dementia
Authors:   Regenerative Neuro Immune Research Institute of South Carolina, Charleston, South Carolina, USA, Dasgupta Subhajit ,   NeuroDrug Research LLC. Charleston, South Carolina, USA, Villa Nina ,   Regenerative Neuro Immune Research Institute of South Carolina, Charleston, South Carolina, USA,   Saint James School of Medicine, Park Ridge, IL, USA, Bandyopadhyay Mausumi ,   NeuroDrug Research LLC. Charleston, South Carolina, USA,   Trident Technical College; North Charleston, South Carolina, USA,   College of Charleston, Charleston, South Carolina, USA
Published: August 2024

Rationale: The systematic review evaluates the results of last fifty years (1973-2023) of clinical trials on pathology and treatment for cognitive impairment including Alzheimer’s dementia (AD dementia). Objectives: Alzheimer’s dementia is a growing public health concern worldwide. The systematic review analyzes the disease confirming pathological findings presented by modern imaging techniques MRI/ PET. In addition, we analyze the success of fifty years of therapeutic advancements of the neurological disabilities and count on the safe drugs to treat clinical conditions of AD dementia. Findings: We followed the PRISMA guidelines to determine the inclusion and exclusion criteria for the selection of clinical records collected from the NCBI databases. We analyzed the drug efficacy results on the three aspects of the AD brain: (a) morphological deformation of the choroid plexus and hippocampus; (b) senile plaques with amyloid beta42 (Abeta42) including hyperintensities of neurons; and (c) inhibitory action of acetylcholinesterase enzyme. The pathological findings include detection of Abeta42 plaques in cerebral cortex and retention ability of trial drugs in cerebrospinal fluid versus blood plasma of AD patients in the context of disease progression and treatment efficacy. The clinical trial records demonstrated evidence of genetic susceptibility factor(s) clustered in European populations. The susceptibility is also found due to mutations in the presenilin-1 gene and expression of the ApoEε-allele among the population. The clinical records demonstrate moderate efficacy of cholinesterase inhibitors Donepezil and Rivastigmine in improving cognition. The antibodies aducanumab, donanemab, and lecanemab show low to moderate success in removing plaques and reducing plasma Abeta burden. Conclusion: The cholinesterase inhibitors demonstrate moderate success in improving cognition. However, the overall efficacy of antibody treatment was poor. The findings suggest a need for new generation drugs which can clear plaques and improve cognition for AD.
Pandemia da COVID-19, vacinação e atividades acadêmicas no curso de Odontologia
Authors: Emerick Vanessa dos Anjos , Silveira Roberto da Gama , Brum Sileno Correa , Freitas Fátima Cristina Natal de , Campello Andrea Fagundes , Gasperini Flávio Marcos , Araújo Leopoldo Miranda
Published: August 2024

O presente estudo teve por objetivo analisar a incidência de COVID-19 entre acadêmicos de odontologia bem como identificar o nível de adesão à vacinação entre os estudantes. Foi realizado um estudo observacional, retrospectivo, transversal, individualizado, referente ao período de março de 2020 a julho de 2023. Foram incluídos neste estudo, acadêmicos do primeiro ao último período do curso de graduação em Odontologia de uma instituição de ensino localizada em um município da Baixada Fluminense - RJ, que voluntariamente aceitaram participar da pesquisa. O questionário foi aplicado pelo Google Forms, em sua primeira página constava o Termo de Consentimento Livre e Esclarecido, com a concordância em participar da pesquisa. Foram respondidos 92 questionários, sendo 72,2% sexo feminino, 58,7% possuíam idade entre 18 e 27 anos, 64,1% eram solteiros, 87% atuam nas práticas clínicas. Quase metade dos participantes (42,4%) foram infectados pela COVID-19, quanto à adesão à vacinação foi significativamente alta, com a totalidade (100%) na primeira e 97,8% dos participantes na segunda dose. Houve predominância da Pfizer tanto na primeira quanto segunda dose, seguida pela Astra Zeneca.
A utilização da técnica de Khoury para aumentos verticais de rebordos alveolares atróficos: Uma revisão sistemática
Authors: Oliveira André Almeida de , Viau Karen Tamires , Katsui Ana Luísa Bacile , Ribeiro Alice Vaccari , Ferreira Tulio Avelar , Pereira Emilly Anne Teixeira , Soller Isabeli Lao
Published: August 2024

Uma das condições mais importantes a serem considerados em reabilitações com implantes está associado a quantidade e qualidade óssea que se encontra disponível para o ato cirúrgico, estabilidade primária do implante e a sua manutenção a longo prazo. Diferentes técnicas para aumento de espessura e altura ósseas têm sido desenvolvidas, determinação de qual técnica a ser utilizada depende diretamente de alguns fatores, entre eles a extensão e localização do defeito ósseo. Uma das opções que vem sendo amplamente discutida é a técnica de Khoury ou técnica de Split Bone Block (SBB) que propõem a fixação de blocos ósseos autógenos mais finos, em forma de lâminas ósseas, associados ao preenchimento com osso particulado e acesso tunelizado. Muitos estudos, tem demonstrado bons resultados relacionados a esse tipo de técnica, apresentando ganhos em altura óssea satisfatórios, favoráveis para o sucesso do tratamento. Assim o objetivo do presente estudo, foi revisar os conceitos acerca das reconstruções ósseas verticais e trazer os principais aspectos e resultados relacionados a técnica de Khoury. Desta forma, espera-se fornecer melhor embasamento científico para o professional implantodontista no momento da seleção desta técnica. Para isso, realizou-se uma revisão sistemática onde os resultados mostraram que a técnica de Khoury apresenta-se como excelente alternativa para ganhos ósseos verticais, sendo indicada para ganhos verticais previamente a cirurgia de implantes dentários.
Ceratocisto odontogênico: tratamento com a solução de Carnoy - Revisão de literatura
Authors: Silva Clenya Fernanda de Jesus da , Brasiliano Bruna de Siqueira , Torres Aline Batista , Sousa Luan Rodrigues de , Saboia Rafael Sousa de Carvalho
Published: August 2024

O Ceratocisto Odontogênico (CO) é uma lesão conhecida por sua alta taxa de recorrência e sua capacidade de infiltração em tecidos locais na região dos maxilares. Objetivo: Analisar a eficácia da solução de Carnoy como terapia coadjuvante para a enucleação do CO, buscando contribuir com informações atualizadas para acadêmicos e profissionais da área. Metodologia: Uma revisão de literatura foi realizada utilizando artigos científicos disponíveis na Biblioteca Virtual em Saúde (BVS) e PubMed, publicados entre os anos de 2016 e 2023, que abordam a utilização da solução de Carnoy como tratamento adjuvante para o CO. Discussão: há estudos que indicaram resultados promissores com o uso da solução de Carnoy como terapia adjuvante para o CO em conjunto com a técnica cirúrgica indicada.Conclusão: Esta pesquisa oferece uma visão abrangente do uso da solução de Carnoy como terapia adjuvante no tratamento do ceratocisto odontogênico apontando sua acessibilidade e custo relativamente baixo a tornam uma opção atrativa para cirurgiões bucais em diversas configurações clínicas.
Terapias de células-tronco no tratamento de doenças neurodegenerativas: Uma revisão da literatura
Authors: Mendes Luis Miguel Carvalho , Lino Lucas Arruda , Castro Neto Antonio Alves de , Radtke Ana Carolyne Portela , Seixas Carlos Henrique Aires Magalhães , Oliveira Kallyne Rodrigues de , Batista Lívia Peixoto , Almeida Zaine Santos de , Ferreira Alexandre Magno dos Santos , Borges Carlos Samuel Lemos , Lima Mariana Gomes de , Aguiar Gustavo Daniel dos Santos Sousa
Published: August 2024

Introdução: O avanço das terapias com células-tronco representa um marco significativo na medicina regenerativa, oferecendo novas perspectivas para o tratamento de doenças neurodegenerativas. Células-tronco pluripotentes induzidas (iPSCs) e células-tronco embrionárias (ESCs) emergem como opções promissoras para a regeneração neuronal, especialmente em condições como a doença de Parkinson. No entanto, a transição dessas terapias da pesquisa para a prática clínica enfrenta desafios consideráveis. Objetivos: Este artigo tem como objetivo revisar a literatura atual sobre a utilização de terapias com células-tronco no tratamento de doenças neurodegenerativas, abordando os avanços recentes, os tipos de células utilizadas, os mecanismos de ação e os desafios persistentes. A revisão visa fornecer uma visão abrangente dos progressos e limitações nesta área, contribuindo para o desenvolvimento de estratégias terapêuticas mais eficazes. Resultados: A revisão revelou que tanto as iPSCs quanto as ESCs têm o potencial de se diferenciar em diversos tipos de células neuronais, possibilitando a substituição de neurônios danificados. Ensaios clínicos e pré-clínicos indicam melhorias na função motora e cognitiva, com destaque para o tratamento da doença de Parkinson. No entanto, a aplicação prática dessas terapias enfrenta desafios como a formação de tumores, rejeição imunológica e a necessidade de integração funcional das células transplantadas. As células-tronco mesenquimatosas (MSCs) também mostram promessa, especialmente por sua menor controvérsia ética e facilidade de obtenção. Conclusão: As terapias com células-tronco têm um potencial transformador para o tratamento de doenças neurodegenerativas, oferecendo esperança para melhorias significativas na qualidade de vida dos pacientes. No entanto, a superação dos desafios associados, como segurança e eficácia a longo prazo, é crucial para a implementação bem-sucedida dessas terapias. Avanços contínuos na pesquisa e desenvolvimento são essenciais para realizar plenamente o potencial terapêutico das células-tronco.
Eficiência de bioestimulante combinado à escarificação mecânica na germinação de sementes de flamboyant
Authors: Souza Hendrick da Costa de , Machado Paulo Roberto , Papke Irmfried Henrique , Mantovani Nilton Cesar , Pasini Rafael Antonio
Published: August 2024

Este estudo teve como objetivo avaliar o efeito de diferentes concentrações do bioestimulante Stimulate® na superação da dormência, germinação e desenvolvimento de plântulas de flamboyant (Delonix regia). Foram utilizadas concentrações de Stimulate® de 2,5; 5,0; 7,5 e 10,0 ml L-1, com as sementes imersas por uma hora. As sementes testadas incluíram tanto as com tegumento intacto quanto as escarificadas com lixa d'água Nº 120 na posição oposta ao embrião, seguindo um esquema fatorial 5x2. Os tratamentos foram dispostos em um delineamento inteiramente casualizado, com as sementes semeadas em tubetes contendo substrato comercial. Os resultados mostraram uma interação significativa (p<0,05) entre os fatores bioestimulante e escarificação mecânica para todas as variáveis analisadas. A combinação de Stimulate® com a escarificação mecânica favoreceu a germinação das sementes de flamboyant. Contudo, a escarificação mecânica isoladamente resultou em maior formação de folhas e em crescimento superior tanto em altura quanto em diâmetro das plântulas. Assim, enquanto a combinação de bioestimulante e escarificação promoveu a germinação, a escarificação por si só foi suficiente para um melhor desenvolvimento das plântulas, tornando o uso do bioestimulante desnecessário.
Pengendalian Mutu Kompetensi Guru Melalui Program Supervisi Akademik
Authors: Agustina Anna , Failasuf Fadli
Published: August 2024

Abstract: The aim of the academic supervision program is to improve the quality of teaching learning process as well as the teacher’s teaching competency. Improving the quality of teachers, both in professional and pedagogical competence, is surely provide huge benefit in improving the quality of learning. However, there are some problems found in the implementation of the teacher supervision program that make the supervision less optimal. The reason is the inconsistency of the implementation of this program. Moreover, this program seems to be implemented only for formality.
This research aimed to determine the ongoing process of academic supervision at SMPIT Assalaam Boarding School (Assalaam Islamic Integrated Boarding School) Pekalongan. The research was carried out using a descriptive qualitative method, the required data was obtained through a process of interviews, discussions and documentation. The results of the research show that the academic supervision activities carried out at SMPIT Assalaam Boarding School Pekalongan have fulfilled the principles of supervision. Academic supervision is carried out to oversee the learning process as an institution's effort to provide quality assurance of education. Academic supervision is carried out through the following stages: the first is the socialization of the supervision program; the second is consultation on learning tools; the third is a class visit to the target teacher to be supervised; the fourth is a reflection on the implementation of teaching and learning activities; the fifth is scoring the results of academic supervision as a conclusion on the teacher's competency achievements; and then the preparation of follow-up activities of the supervision. Through academic supervision activities, school principals can provide guidance to teachers to improve the quality of learning
STATE POLICY, HUMAN CAPITAL AND INTERNATIONAL ECONOMIC RELATIONS IN THE CONTEXT OF REFORMING LOCAL SELF-GOVERNMENT BODIES THROUGH DIGITALIZATION, ARTIFICIAL INTELLIGENCE AND SOCIO-ECONOMIC TRANSFORMATIONS
Authors: SERHIEIEV VIACHESLAV , GRUNTKOVSKIY VOLODYMYR , DZVINCHUK DMYTRO , KHARECHKO DMYTRO , LIUTYI MARK , KOVALSKA NATALIA
Published: August 2024

The study examines human capital as a set of socio-economic relations and as one of the determining factors of economic growth. The main attention is paid to the analysis of opportunities to improve the quality of human capital at the local level, based on mechanisms of cooperation among stakeholders and reforming the landscape of local self-government - in particular, through the creation of innovation hubs, the implementation of digitalization projects, and the expansion of the use of artificial intelligence technologies. The opportunities and benefits of direct participation of local communities in international economic relations and global supply chains are demonstrated.
Species of the OnobrychisGenus as Promising Species of Azerbaijan Flora
Authors: Jafarova Sh.
Published: August 2024

One of the tasks of pharmacy is to find affordable raw materials for herbal medicines. The studies were conducted in Azerbaijan. The results of the studies indicate that Onobrychis species are a rich source of β-arbutin. Arbutin (4-hydroxyphenyl-β-D-glucopyranoside), a monoglycoside form of hydroxyquinone, has been used in the field of cosmetology for several decades due to its effectiveness in the treatment of hyperpigmentation and removal of freckles. Onobrychis species are of significant ecological and economic importance, and also demonstrate intriguing therapeutic properties that have attracted attention in the field of medicine. The presence of bioactive compounds such as flavonoids and phenols, which are known for their antioxidant properties, is another noteworthy aspect. Antioxidants play a crucial role in neutralizing harmful free radicals in the body, which are involved in a wide range of diseases and the aging process. Onobrychis has anti-inflammatory properties. It is well known that inflammation is a common factor in many chronic diseases. Plants have antimicrobial, immunostimulating, hypoglycemic, hypocholesterolemic, gastrointestinal tract normalizing and vascular wall strengthening properties. The study of Onobrychis opens up potential prospects in the field of creating natural products.
Analysis of the Species Composition of Wood and Shrubs Species, Their Role in the Structure of City Parks of Osh
Authors: Shamshiev B. , Absatarov R. , Mametova K.
Published: August 2024

In the city of Osh, one of the acute problems when using wood species in landscape design is the study of their ecological properties in relation to the environment. The planting of trees in urban parks, squares along streets and boulevards is influenced by various environmental factors. In such conditions, the study of the ecological state and viability of plants is relevant, since woody plants perform sanitary, hygienic and aesthetic functions in an urbanized environment. The main purpose of this scientific article is to identify in the conditions of the city of Osh, the peculiarities of the development of ornamental species of woody and shrubby plants, the ecological justification of their reconstruction, to improve the sanitary and hygienic condition and the development of practical recommendations in landscape works. The study of the characteristics of tree and shrub species and the results obtained to assess their role in the structure of urban parks in Osh will help to improve their decorative qualities, the correct choice of their placement, care and improvement of the urban environment. The results of the work can also be used in the construction and reconstruction of green spaces in parks in the city of Osh, as well as in the improvement of other public facilities in the city. The practical recommendations obtained from the results of the study initiate a large-scale reconstruction of planted species of trees and shrubs in parks, squares and along modern streets.
Frequency of Injuries and Deaths Due to Traffic Accidents Caused by the Driver, Bishkek
Authors: Kurmanova A.
Published: August 2024

Road traffic injuries due to the severity of their adverse consequences are one of the priority health problems both in the Kyrgyz Republic and around the world. In Bishkek, the most common causes of traffic accidents caused by the driver were violations of the rules of maneuvering, violation of the rules for the passage of a pedestrian, crossing, non-observance of the rules of priority of travel, road signs, signals, speeding, driving into the oncoming lane, double overtaking, driving while intoxicated, non-observance of distance. However, it should be taken into account that for reasons such as violation of maneuvering rules (2.5 times), violations of the rules of passage of a pedestrian, crossing (2.9 times), non-compliance with the rules of priority of passage (1.6), disobedience to road signs, signals (2.9 times), driving into the oncoming lane, double overtaking (1.8 times), drunk driving (1.7 times), non-compliance with the distance (3.0 times), violation of the rules for passing inspection, use, reception (3.2 times), the frequency of injuries increased. In general, in Bishkek, for the period from 2016 to 2022, 549 people died from road accidents, of which 418 (76.1%) were caused by the driver of passenger vehicles. The highest proportion, both in general and through the fault of the driver of passenger vehicles, was made up of those who died from traffic accidents due to violation of maneuvering rules, violation of pedestrian, crossing, speeding.
Microscopic Polyangiitis as a Multidisciplinary Problem (Literature Review and Case Report)
Authors: Murkamilov I. , Aitbaev K. , Raimzhanov Z. , Yusupova Z. , Yusupova T. , Khakimov Sh. , Nurmatov Т. , Solizhonov Zh. , Ymankulov D.
Published: August 2024

Microscopic polyangiitis is a necrotizing vasculitis characterized by systemic involvement of capillaries, venules, and arterioles. The average age of patients at the time of microscopic polyangiitis verification is 42 (51-65) years. Almost all patients with microscopic polyangiitis have antineutrophil cytoplasmic antibodies. Antibodies to myeloperoxidase are more common than antibodies to proteinase-3. The disease is most commonly characterized by involvement of small vessels in the kidneys and lungs, as well as a high frequency of end-stage chronic kidney disease and mortality. Patients with microscopic polyangiitis have a low risk of exacerbation and a low frequency of arterial hypertension despite renal involvement. The article discusses the clinical spectrum of organ involvement in microscopic polyangiitis and presents a case description of a 39-year-old woman with renal, lung, and heart involvement against the background of concomitant bronchiectatic disease. High titers of myeloperoxidase antibodies were detected in the enzyme immunoassay. Patient R., 39 years old, was diagnosed with microscopic polyangiitis on August 31, 2021, and died on June 28, 2024, with a disease duration of 35 months (147 weeks, 3 years).
Concomitant Diseases in Pregnant Women Suffering with Chronic Viral Hepatitis B and C
Authors: Abdikerimova M. , Kanatbekova A. , Abdikerimov M.
Published: August 2024

The work identified concomitant diseases in 120 pregnant women suffering from chronic viral hepatitis B and C (CHB and CHC), aged 19 to 30 years. In the structure of extragenital pathology, the largest percentage belongs to diseases of the gastrointestinal tract, which was detected in 71.0% of 69 patients with CHB, in 76.5% of 51 pregnant women with CHC and in 42.1% of 57 relatively healthy pregnant women. Among the nosological forms were mainly chronic gastritis, chronic gastroduodenitis, biliary dyskinesia and chronic pancreatitis. Chronic viral hepatitis in pregnant women determines a high incidence of gastrointestinal tract damage due to biliary dyskinesia, apparently associated with viral liver damage. Urogenital infections among pregnant women are significantly more common in patients with CHB (59.4%) and CHC (80.3%) (p <0.05) than in those without liver pathology (21.5%). Among the urogenital infections, the most common was a combination of chlamydia and candidiasis, and less frequently, trichomonas infection, and only one patient was diagnosed with syphilis. Chronic viral hepatitis is a factor contributing to the development of urogenital infection in pregnant women.
Lung Lesions in Exposure to Pesticides and Herbicides (Literature Review and Case Report)
Authors: Murkamilov I. , Aitbaev K. , Yusupov F. , Raimzhanov Z. , Yusupova Z. , Khakimov Sh. , Nurmatov Т. , Solizhonov Zh. , Ymankulov D.
Published: August 2024

Pesticides (herbicides, insecticides, fungicides, zoocides) are mixtures of substances of chemical or biological origin used to destroy or inhibit the growth of microorganisms, fungi, harmful vegetation, and other living organisms. These organisms damage crop and livestock production, degrade the quality of agricultural products, materials, and goods. Pesticides are classified into organic, and inorganic based on their chemical composition. About 1,000 active ingredients are used in pesticides, of which 310 are considered particularly hazardous. Extensive use of pesticides leads to the destruction of biocenoses and the emergence of various pathological changes in the human body. Among the pesticide ingredients with acute and chronic toxicity, abamectin, aluminum phosphide, beta-cyfluthrin, bifenthrin, chlorpyrifos, deltamethrin, diazinon, fenamiphos, malathion, methomyl, oxamyl, primicarb, propargite, tebuconazole, chlorothalonil, bromoxynil, bromoxynil octanoate, brodifacoum, and others stand out. In conditions of pesticide load on soils, the frequency of allergic and respiratory diseases is steadily increasing. Chronic obstructive pulmonary disease (COPD), caused by smoking and pesticides, leads to loss of working capacity and social activity, as well as significant costs for treatment and rehabilitation. The article discusses the pathogenetic and clinical aspects of the formation of COPD under conditions of synergy (smoking + pesticides). Various clinical phenotypes of COPD are also considered. A clinical case of a patient with COPD caused by smoking and prolonged contact with pesticides (mosplan, zellek-super, goal 2E), which manifested with chronic respiratory failure, multifocal atherosclerosis, and heart failure, is described.
Development of a Computer Model for Determining the Composite Fuel Composition and Quality
Authors: Tazhikbaeva S. , Tashpolotov Y.
Published: August 2024

This article develops a computer model for determining the composition and quality of composite fuel. Coal-water fuel was considered as the object of study. Empirical formulas were used to determine the calorific value of composite fuel, and their results were compared with experimental results. Using the Python program, a model was created to determine the composition and calorific value of coal-water fuel using the Mendeleev and Knievel formulas. According to the created computer model, it is shown that the calorific value of coal-water fuel depends to a greater extent on carbon, hydrogen and oxygen than on other components in its composition. The decrease in the amount of carbon and hydrogen in coal-water fuel led to a decrease in the heat of combustion of the fuel. It is also shown that oxygen and heat of combustion are inversely proportional.
The Importance of Psychosocial Work in the Aviation Industry
Authors: Salmorbekova R. , Omorbaeva A. , Myrzalieva T.
Published: August 2024

This article explores the importance and relevance of psychosocial work in the airline industry. The author draws attention to the fact that aviation, being under a high level of stress and responsibility, requires appropriate psychological and social support for pilots, crews and other workers in this industry. The article also describes the main goals and objectives of psychosocial work in aviation, including supporting psychological well-being, preventing mental disorders and counseling workers experiencing stress and anxiety. In conclusion, highlights the importance of psychosocial work in aviation to ensure aviation safety and the overall well-being of air transport workers. Thus, it covers the main aspects of the importance of psychosocial work in aviation, its benefits and objectives, providing readers with an overview of the content of the article.
Formation of Key Competencies by Organizing Independent Work in Geometry
Authors: Tagaeva D. , Kaldybaev S.
Published: August 2024

In the process of learning geometry in high school, students constantly encounter various difficulties both when solving problems and examples, and when studying theoretical material. By teaching these difficulties, skills and abilities of independent work are developed. We will focus only on developing the skills of independent work through tasks with life content.
The Problem of Forming Information Competence in the Process of Teaching Kyrgyz Language to Students of the Faculty of Journalism
Authors: Namazbekova A. , Sydykbaeva M.
Published: August 2024

The article is devoted to the study of the problem of developing information competence in the process of teaching the Kyrgyz language to students of the Faculty of Journalism. This article discusses the terms “competence”, “competence”, “information competence” in the linguodidactic aspect. The article discusses current issues of teaching students of the Faculty of Journalism the Kyrgyz language according to the established standards of the State Educational Standard of Higher Professional Education. Formation of information competence of students of the Faculty of Journalism is an important aspect of their professional development. After all, a future journalist must be ready to work in a fast-moving information space, where the importance of information and the ability to present it play a key role. The problem is that a modern journalist must not only be able to collect and analyze information, but also be able to present it in accordance with the requirements of various formats — from print publications to online news. The goal is to study the problem of developing skills in a future journalist, with the help of which a specialist can adequately respond to the needs of modern society, having the skills to effectively search and analyze information, as well as the ability to present it in accordance with the requirements of various formats. The research materials were scientific sources. Research methods: analysis and synthesis of scientific sources.
S. Shamurzin - Kyrgyz Soviet and State Figure
Authors: Bekmurzaeva G.
Published: August 2024

S. Shamurzin’s career began in 1923 with admission to the Kyrgyz Institute in Alma-Ata. In the fall of 1925, the Kyrgyz students at the institute were transferred to the Kyrgyz Pedagogical College in the city of Pishpek, from which S. Shamurzin graduated in 1929 with a degree in first-level teacher. In 1928, while studying at the institute, he was accepted as a member of the All-Union Communist Party (Bolsheviks) by the Frunze City Party Committee. From 1930 to 1938 S. Shamurzin in responsible Soviet party positions, works in all sectors of the national economy of the KASSR and KSSR.
Trade Union Organizations of Kyrgyzstan in the 1920-1930s of the 20th Century
Authors: Osmonov S. , Bekmurzaeva G. , Tobakalov Ch. , Asilbekuulu B.
Published: August 2024

In connection with the formation of the Kirghiz Autonomous Soviet Socialist Republic in August 1927, a reorganization of the structure of trade unions was carried out: regional departments were transformed into republican ones, district ones - into canton ones. Trade unions of Kyrgyzstan, under the leadership of the Kyrgyz regional committee of the CPSU (b), fought for the implementation of the decisions of the XIV and XV congresses of the CPSU (b), sought to increase the creative activity of workers in the reconstruction of old and construction of new industrial enterprises, in the transformation of agriculture. At the II Congress of Trade Unions of Kyrgyzstan, held in November 1926, it was decided to reorganize their work with the slogan “Facing production”, about attracting workers to actively participate in production management; special attention was paid to the training of national workers.
Interrogating the All-Knowing Detective Trope: Popular Memory Myths and Dismantling the Detective in Howard Engel’s Memory Book
Authors: Cave Kylene N.
Published: August 2024

Howard Engel’s novel Memory Book (2005), written after the author’s experience of stroke, critiques crime fiction’s platitudinous handling of memory and cognition. In tracing a brief history of memory in the genre and its reliance on popularised memory myths to construct the exceptional detective figure, this article considers alternative modes of detection that disavow the detective as the epistemic centre of the text.
Prognostic indicators of vector electrocardiography in patients with chronic heart failure with reduced left ventricular ejection fraction
Authors: Vashtanian A. K. , Uskach T. M. , Amanatova V. A. , Drozdov D. V. , Sakhnova T. A. , Blinova E. V.
Published: August 2024

Relevance. Computed vector electrocardiography (VECG) is a method of visualization of the total electrical vector of the heart in 3‑dimensional space based on 12 leads and a known computational procedure. VECG may be an additional method to assess the severity and prognosis of patients with chronic heart failure (CHF).

Objective. To determine VECG parameters associated with unfavorable prognosis in patients with CHF with reduced ejection fraction (CHFpEF).

Materials and methods. VECGs of 100 patients with CHFpEF were analyzed. All patients underwent baseline clinical examination, echocardiography and natriuretic peptide (NT-proBNP) determination. Patients with both ischemic (55 patients, of whom 10 died) and non-ischemic (45 patients, of whom 6 died) etiologies were included. During follow-up for 24 months, fatal outcomes were recorded. The correlation of ECG and NT-proBNP parameters with patients’ prognosis was evaluated.

Results. A total of 16 patients died in the study. According to VECG data the surviving patients had lower spatial QRS-T angle in comparison with the deceased ones (p=0,025). There was a trend towards lower planarity index in the group of deceased patients (p=0.09). ROC-analysis was carried out, according to the results of which with sensitivity 76,5% and specificity 62,7% the cut-off value of 156º of QRS-T spatial angle was obtained, exceeding which the probability of lethal outcome will increase (p=0,002). There was a correlation between lethal outcome in patients with a QRS-T angle value greater than 156º and NT-proBNP level (p=0.017). The threshold value of unfavorable prognosis for NT-proBNP was 927.1 pg/ml.

Conclusion. The VECG method is available and promising in the diagnosis and monitoring of patients with CHFpEF. The most informative parameters of ECG for detection of suspicion of CHFpEF are spatial QRS-T angle and planarity index. The results obtained in this study allow us to speak about the prognostic value of the QRS-T angle for patients with CHFpEF.