bluuebunny/crossref_metadata_2025 huggingface dataset:
The Herbal Treatment of Osteoarthritis
Authors: Verma Vikrant
Published: March 2023

Osteoarthritis is widely acknowledged as the most common, devastating, and diverse
ailment that wreaks havoc on people's lives across the world. In the elderly, it is estimated that 10%
of males and 18% of women over the age of 60 are affected and its frequency and incidence are increasing
in the present scenario. Herbal medicines appear to be safe and effective with antiosteoarthritic
effects that help in increased alleviation of symptoms and/or impairment and consist
of numerous phytochemicals that have been scientifically verified and confirmed with antiosteoarthritic
activity. Currently, there is no definitive cure for osteoarthritis, and there are no effective
therapies that can stop or halt the progression of the disease. However, there are a variety of
therapies available, ranging from new to old. Intra-articular injections, topical treatments, and oral
medicines are altogether FDA-approved replacements for surgery. These all modes of treatment
may prove fatal sometimes and are not always successful. Herbal medicines have been utilized
worldwide for the treatment of osteoarthritis. This review mainly focuses on the treatment approach
of osteoarthritis with the herbal medicines available, because of the side effects and toxicities, and
unwanted symptoms of the present treatments.
Natural Herbs Polishing Memory: Neuroprotection against Alzheimer's Disease
Authors: Thakkur Manisha , Dilnashin Hagera , Keshri Priyanka Kumari
Published: March 2023

Alzheimer's Disease (AD) is an irreversible and progressive neurodegenerative disorder that directly deteriorates the memory and cognitive function of the human brain in such a way that a person finds difficulties in dealing with daily life tasks. It is characterized by irregular neurofibrillary tangles (NFTs), intraneuronal accumulation, and the development of senile plaque (SP) consisting of abnormal polypeptide accumulation called βA4 amyloid. The pathophysiology can be collectively explained by five major hypotheses that are amyloid β (A β) hypothesis, the hyperphosporelated tau hypothesis, chronic inflammation, the cholinergic hypothesis, and the metal ion hypothesis. WHO estimated that a total of 40 million people worldwide are tested for the ill effects of dementia, and this is predicted to be twice as high as 114 million by around 2050. Currently, FDA-approved treatments for Alzheimer’s involve Donepezil, Rivastigmine, Galantamine, and Memantine that do not act specifically against Alzheimer's pathology and are also associated with loss of appetite, increased frequency of bowel movements, mental confusion, and dizziness as their side effects promote the approach to disease-modifying drugs. Nowadays, treatment with herbal medicines is a powerful alternative worldwide due to their high safety of margin against the side effects of allopathic drugs. Herbs are not restricted to a specific activity; they are generally enclosed with lignans, flavonoids, tannins, triterpenes, sterols, and alkaloids with wide pharmacological activities, such as antiinflammatory, anti-amyloidogenic, anti-cholinesterase, and anti-oxidant effects. Many herbal plants of India, such as Glycyrrhiza glabra, Acorus calamus, Convolvulus pluricaulis, Centella asiatica, Sesbania grandiflora, etc., have already proved their efficacies in treating dementia in various scientific studies.
Immunoinformatics - Role in the Identification of New Classes of Antimicrobials
Authors: G. Sunil Krishnan , Joshi Amit , Kaushik Vikas
Published: March 2023

Antimicrobials help to restrain or fix the arising irresistible infection in a
superior manner anyway, and living creatures require another class of antimicrobials.
The new classes of antimicrobial development for the emerging and reemerging
pathogenic microbes, the evolution of multidrug-resistant microbes, and the threat of
bioterrorism or bioweapons are a global necessity. Integrative genomics, proteomics,
and immunoinformatics are powerful tool approaches to design and develop
antimicrobials promptly and economically. Natural and artificial antimicrobials for
humans, animals, and avians are designed and developed using various
immunoinformatics databases, tools, and algorithms. Immunoinformatics plays a great
role in dissecting and deciphering genomics, proteomics, and clinical enormous
information effectively. The artificial neural network, quantitative matrices and support
vector machine algorithms based on immunoinformatics tools would be strong for the
planning of adequate customized antimicrobials. The immunoinformatics strategies for
antimicrobial improvement are staggeringly utilized for improving living creatures'
well-being. The usage of artificial intelligence and machine learning tools is also an
asset for immunoinformatics way of antimicrobial design and development. In the new
time of pandemic illnesses, progressed immunoinformatics devices play a great role in
improving antimicrobials. 
Analisis Perencanaan Pembangunan Daerah dalam Pemanfaatan Dana Kelurahan di Kota Bima
Authors: Fazhur Rahman
Published: March 2023

The background of this research is the policy of allocation of urban village funds from the central government at the end of 2018.This is carried out to stimulate local governments, including Bima City to support sub-district village development through local government budget (APBD) allocation of 5%. This research is qualitative research. The results of this study is seen from the lack of authority (decentralization) given to the chief of the administrative village with limited space and role, the community is less empowered and involved in the planning and implementation of village funds. Meanwhile, the factors affecting the management of the village funds in Bima City are the dominance of regional agencies; human resources; rapid changes in the organizational structure; the inaccuracy of understanding the planning of village funds; Lack of transparency and dissemination of information.
Corte a ras en caña panelera
Authors:   Ministerio de Agricultura y Desarrollo Rural, Bogotá (Colombia),   Corporación colombiana de investigación agropecuaria, Mosquera (Colombia)
Published: March 2023

El corte a ras en la cosecha de caña panelera, fomenta una buena producción. En este clip tecnológico se presenta el paso a paso para la buena práctica de manejo de corte a ras en caña panelera.
Characterization of the microbial community associated with the roots of joyapa (Macleania rupestris) and the effect of fungal isolates on seedling development
Authors: Curillo Diana , Cevallos-Cevallos Juan Manuel , Chica Eduardo , Peña Denisse
Published: March 2023

Macleania rupestris is a native Ericaceae with high potential benefits for health and the environment. Characterizing the interactions between M. rupestris and associated fungi is vital to supporting the plant's conservation and future domestication. However, little is known about the relationship between plant growth-promoting endophytes and M. rupestris. To learn more about the soil-associated microbiota of M. rupestris, we analyzed endophyte communities associated with the plant's rhizosphere and surrounding soil using nanopore sequencing. Additionally, fungal endophyte cultivable strains were isolated from the roots of M. rupestris to evaluate their growth-promoting activity on seedlings by applying a strain inoculation bioassay. Over 1000 genera were identified using nanopore sequencing, Bradyrhizobium and Mesorhizobium the most abundant in all samples analyzed.

Similarly, six cultivable fungi were characterized by the molecular markers ITS (internal transcribed spacer) and LSU (large subunit). Amongst all isolates, Clonostachys rosea and Trichoderma paravidescens positively impacted seedlings' development. This study shows the potential of fungal strains as inoculants for the potential domestication of Macleania rupestris.

Keywords: Endophyte, growth promoter, Macleania rupestris, microbial communities
Proposal of a Method for Transferring High-Quality Scientific Literature Data to Virtual Patient Cases Using Categorical Data Generated by Bernoulli-Distributed Random Values: Development and Prototypical Implementation (Preprint)
Authors: Schmidt Christian , Kesztyüs Dorothea , Haag Martin , Wilhelm Manfred , Kesztyüs Tibor
Published: March 2023

BACKGROUND

Teaching medicine is a complex task because medical teachers are also involved in clinical practice and research and the availability of cases with rare diseases is very restricted. Automatic creation of virtual patient cases would be a great benefit, saving time and providing a wider choice of virtual patient cases for student training.

OBJECTIVE

This study explored whether the medical literature provides usable quantifiable information on rare diseases. The study implemented a computerized method that simulates basic clinical patient cases utilizing probabilities of symptom occurrence for a disease.

METHODS

Medical literature was searched for suitable rare diseases and the required information on the respective probabilities of specific symptoms. We developed a statistical script that delivers basic virtual patient cases with random symptom complexes generated by Bernoulli experiments, according to probabilities reported in the literature. The number of runs and thus the number of patient cases generated are arbitrary.

RESULTS

We illustrated the function of our generator with the exemplary diagnosis “brain abscess” with the related symptoms “headache, mental status change, focal neurologic deficit, fever, seizure, nausea and vomiting, nuchal rigidity, and papilledema” and the respective probabilities from the literature. With a growing number of repetitions of the Bernoulli experiment, the relative frequencies of occurrence increasingly converged with the probabilities from the literature. For example, the relative frequency for headache after 10.000 repetitions was 0.7267 and, after rounding, equaled the mean value of the probability range of 0.73 reported in the literature. The same applied to the other symptoms.

CONCLUSIONS

The medical literature provides specific information on characteristics of rare diseases that can be transferred to probabilities. The results of our computerized method suggest that automated creation of virtual patient cases based on these probabilities is possible. With additional information provided in the literature, an extension of the generator can be implemented in further research.
Diaspora Remittances-Stock Market Development: An Inclusive Framework for Zimbabwe
Authors: Mukoka Shame , Nyamusa Tracy
Published: March 2023

This study sought to determine an inclusive framework for diaspora remittances growth and stock market development. Stock market plays an important role in economic development and growth by creating liquidity and allocation of resources to deficit sectors of the economy. The study used the ARDL-ECM in the determination of the relationship between the two variables, using data for the period 1990 to 2020. Eviews Version 9.0 Statistical Package was used to run the regressions. This study found that Diaspora Remittances have an insignificant negative relationship with Stock Market Development for Zimbabwe. This may have been due to Diaspora Remittances flowing through informal channels and, therefore, may have not be tapped on for Stock Market Development. The study recommend an inclusive framework that allows the government to take measures to boost investor confidence, to encourage the diaspora population to invest more in Zimbabwe through elimination of corruption, having stable political environment, formulation of policies that ensures stability in the macroeconomic environment, and having the right governance systems. Encouraging campaigns which must be run by the government and nongovernmental organizations educating Zimbabweans in the diaspora of the benefits of investing home. Allowing the government to set up formal diaspora remitting channels which have minimal charges to encourage more remittances to flow through the channels. Government must also offer favourable interest rates on bond holders so as to lure those in the diaspora to invest in the stock market.
Android Application for Online Advertising of Products and Services
Authors: Palle Abhiram Reddy , Hussain Md Shaik Amaan , Nagula Siddharth , Srikanth Royyuru
Published: March 2023

Abstract: In this paper, we study the concept of Advertising, we have developed a mobile application in which various companies and users can advertise their products in our mobile application. and the viewers can see those ads and go through a survey on those products and services-related questions. In this application we have designed two interfaces for the viewer of the ad and the publisher of the ad. As we know nowadays online marketing plays a vital role in increasing sales and revenue, so we developed an application on that domain to users to advertise their products and services, as we said at the start that there are two interfaces in the application, the second interface and the most important interface where the viewer reviews the product and service of the advertiser by answering the survey about the ad’s image or the video that they see in the application, with this the viewer can ignite interest in the product and can try its service or buy those products, for viewing the content in this application the viewer gets coins in return, for viewing every ad in the application it increases the count of the views of the viewer and here one view is equal to one point and here viewer can see only a few numbers of ads per day, when the views reach the prescribed number of views, the views can be converted into rupees and the viewer can withdraw that money from the wallet by adding a bank account or purchase a coupon related to the product or service in the list provided.so It is an application where the viewer views the ads for gaining points and with those points they can either withdraw money or purchase coupons and gift cards, with this application the advertisers gain popularity with their products and services , the viewer if the products more familiar to the interest of the viewer, the viewer may purchase or try the service or product. In this way the application works, which mostly benefits both party’s interests and can be mostly used to increase the sales of the products and services, which in turn leads to profits and betterment of the company or industry.
A Systematic Requirement Analysis for Dynamic Pricing in Retail E-Commerce
Authors: Kumari Archana , Kumar S. Mohan , K Babu Rao
Published: March 2023

Abstract: Retail e-commerce has been exploding recently, with billions of people using the internet to buy goods and services. Due to the vast number of vendors selling similar products to consumers and the high degree of price transparency enjoyed by purchasers, the e-commerce sector is fiercely competitive. Vendors frequently use dynamic pricing, also known as discount pricing, to ensure they generate a healthy profit. In this paper, we present a systematic analysis of the requirements for a modern e-commerce dynamic pricing system. We cover the business, stakeholder, functional, and non-functional requirements of ecommerce dynamic pricing. We additionally offer a generic architecture blueprint based on what we have learned about the requirements for dynamic pricing
Globalization and Tourism-Impact and Prospect
Authors: Majeed Dr. Abdul
Published: March 2023

Abstract: The process of connection and integration between the people, businesses, and governments of other countries is known as globalization. One of the most significant sectors that globalization has an impact on is tourism. This process is supported by information technology, international trade, and investment. National boundaries are being eroded by globalization, a process of economic, social, cultural, and political activities, and this has an impact on tourism. A wide range of economic sectors have been effected due to globalization. This paper summarizes how the tourist industry has been affected by globalization
Acute Abdominal Case Report: Ruptured Ovarian Endometriotic Cyst Concurrent with Acute Appendicitis
Authors: Nareswari Gupita
Published: March 2023

Acute pain of pelvic origin is a common symptom necessitating emergent medical evaluation. Acute pelvic pain in young women can present as a unique diagnostic dilemma. Differential diagnosis in acute pelvis pain can vary according to risk. Possible causes span a gamut from functional ovarian cysts that require routine follow-up to adnexal torsion and ectopic pregnancy requiring urgent surgical management.
This case report illustrates how concomitant gynecologic disorders can occur in patients with acute appendicitis. The laparoscopic operation revealed a ruptured ovarian endometriotic cyst concurrent with acute appendicitis and was proven by histopathology. This serves as a reminder that even though a rare case is contemporary, two different entities can occur.
Estado de la aplicación del principio de paridad de género en las elecciones nacionales de Costa Rica, período 2022-2026
Authors: Morales-Rodríguez Diego A.
Published: March 2023

Este artículo busca verificar el estado de cumplimiento del principio de paridad o igualdad de género, durante las elecciones nacionales de Costa Rica en el 2022, con el fin de generar un insumo que provoque la reflexión sobre las mejoras y debilidades que aún posee el sistema político electoral costarricense en el cumplimiento efectivo de la participación activa e inclusiva de la ciudadanía en la política nacional. Se realizó un análisis descriptivo de las candidaturas presentadas por los partidos políticos involucrados para todos los puestos a elegir mediante el sufragio, a partir de la información suministrada por el Tribunal Supremo de Elecciones (TSE). Se utilizó como fundamento la normativa costarricense que rige lo electoral y en lo teórico-conceptual el principio de paridad de género en la participación política desde una perspectiva crítica-feminista. Dentro de los hallazgos principales se encuentra que la aplicación del principio de paridad de género en la normativa electoral costarricense ha sido efectiva considerando el incremento de la representación de la mujer en la cantidad de curules que están ocupando en la Asamblea Legislativa; no obstante, se deben concretar más acciones afirmativas que deriven en cambios en los estatutos partidarios, las estructuras partidarias, los mecanismos de inscripción de candidaturas a puestos uninominales, como son la presidencia y vicepresidencias del Poder Ejecutivo y las autoridades de los gobiernos locales, el cambio del concepto sexo, entre otras.
Literacy attainments as prone to communication skills follow-up
Authors: Olmos Jonathan , Garcia Andres
Published: March 2023

This study aimed to look into the impact of educational practices on the
reading and writing skills of learners, with a specific focus on the
gaps and bonds in EFL learning while communication skills carried
follow-ups. The study employed a mixed methodology, which embraced
communication contexts placed in the teaching process, and
self-perceptions of the participants in a multidimensional communication
axis to collect data via surveys, observational forms and exploratory
statistics. The results indicate that while there is a stable level of
variation in terms of reading and writing achievement, there are
setbacks in certain areas such as fill-in-the-blank questions in complex
activities and sentence rewriting tasks. Additionally, the study found
that providing students with picture clues can improve their
performance. The study also suggests that blending both reading and
writing skills in activities can lead to large linkages and improvements
in performance.
A New High-gain DC-DC Converter for solar PV Application
Authors: Zaid Mohammad , khan Farha , Tariq Abu , Khan Mohammad Muktafi Ali
Published: March 2023

The globe is currently seeing an unheard-of drive toward renewable
energy due to growing concerns about climate change. Small, distributed
types of generation, like solar photovoltaic, played a significant part
in shifting to a clean energy future due to economic factors and
governmental laws. DC-DC converters are essential in the generation of
solar PV electricity because they regulate the output voltage relying on
the input voltage. The conventional boost converter (CBC) has minimal
output voltage gain, and voltage stress at a switch is typically
equivalent to the output voltage. The voltage produced by distribution
generation (DG) sources is minimal, necessitating the use of high-gain
boost converters. This proposed study is concerned with the development
of an improved architecture of non-isolated high-gain DC-DC converters
for PV applications, which provides quadratic output voltage gain and
reduced voltage stress across a switch. The proposed configuration of
the converter is comprised of a conventional quadratic boost converter
with a voltage lift cell, which provides a high gain. The topological
benefit is the use of a single switch with a lower number of inductors
which reduces the circuit bulkiness. The developed topology was
contrasted in terms of voltage gain, number of passive components used,
and switch stress with other recently presented topologies. The
simulation was performed using MATLAB/SIMULINK, and the output voltage
gain was verified by prototype experimental results employing the
simulation data.
Low voltage in small left atrium in patients with persistent atrial fibrillation: left atrium diameter alone is not always a predictor of prognosis
Authors: Li Xiaoqin , Yin Chun , Zhang Yuan , Zhang Hao , Li Xiaoli , Wu Wenli , Ran Boli , Xiang YongJing , Fu Biao
Published: March 2023

Background The diameter of the left atrium (LA) is a major index
of prediction for LA fibrosis and ablation outcome in atrial
fibrillation (AF)However, an unenlarged LA may not be associated with
good results in some cases of AF ablation. Objective Exploring
the characteristics and ablation prognosis of the patients with fibrotic
but unenlarged LA Methods Patients with persistent fibrillation
who underwent catheter ablation in our center were analyzed in this
retrospective studyComprehensive low voltage mapped in LA is considered
a fibrotic LAThe patients with fibrotic but unenlarged LA, normal LA,
and fibrotic tissue with enlarged LA were included in Groups A, B, and
C, respectivelyWe compared clinical features, electrophysiological
findings, immediate ablation results, and follow-up outcomes in three
groups. Results We enrolled 9 patients in Group A, 38 in Group B, and 12
in Group CThere were greater proportions of women, low ventricular
rates, and high CHA2DS2-VASC scores in the patients with fibrotic LA
(Groups A and C)At the end of procedure, all of the patients saw
restored sinus rhythm, and the rate of sinus rhythm was lower in Groups
A and C than in Group BAtrial-ventricular block and very-early-stage
recurrence were more common in Group ASinus rhythm maintenance and LA
reversion were rarer in Group A than in Group B or C. Conclusions A
fibrotic but unenlarged LA was more likely to be seen in female with
high CHADS2VA2S scoreIt indicated a poor prognosis for AF ablation.
Multistage evolution of intracontinental basins: the case of the Lusitanian Basin
Authors: Marques Fernando Ornelas , Gaspar Diogo F.A. , Almeida Julio Cesar Horta de , Nogueira Carlos R.
Published: March 2023

The Newfoundland-Iberia rift, which includes the Lusitanian Basin (LB),
has been considered the archetype of a magma-poor rift, but its main
steps are still debated. The new data reported here indicate that the
LB’s eastern border comprises two contrasting types of contact between
continental sediments and Variscan basement: major angular unconformity
and master bounding fault. The unconformable contact could mean a
pre-rift sag basin, or a syn-rift half-graben with flexural boundary in
the E. However, given that newly recognized master NW-SE to NNW-SSE
bounding faults displace the red continental deposits and basal
unconformity by hundreds of meters, we infer that the master bounding
fault is Alpine and displaces the base of a previous sag basin. In the
case of unconformable contact and sag basin, the age of the red
continental deposits would be older than the currently attributed Late
Triassic age, and represent the missing Late Variscan denudation
molasse. It seems therefore that the LB could be a rift basin underlain
by an older and smaller sag basin. Later, Pangaea rifting produced a
full graben, the LB, bounded to the east by a newly mapped master fault
reactivating a major Variscan shear zone in the northern half of the
Lusitanian Basin. A similar development of composite basins can be found
in NE Brazil, where some Mesozoic intracontinental basins also show
evidence of two-stage basin formation, an early sag (Palaeozoic) and a
later rift (Mesozoic).
Surface energy dynamics and canopy structural properties in intact and disturbed forests in the Southern Amazon
Authors: Pinagé Ekena Rangel , Bell David M , Longo Marcos , Silva Carlos Alberto , Csillik Ovidiu , Huete Alfredo R
Published: March 2023

The Brazilian Amazon has been a focus of land development with large
swaths of forests converted to agriculture. Forest degradation by
selective logging and fires has accompanied the advance of the frontier
and has resulted in significant impacts on Amazonian ecosystems. Changes
in forest structure resulting from forest disturbances have large
impacts on the surface energy balance, including on land surface
temperature (LST) and evapotranspiration (ET). The objective of this
study is to assess the effects of forest disturbances on water fluxes
and canopy structural properties in a transitional forest site located
in Mato Grosso State, Southern Amazon. We used ET and LST products from
MODIS and Landsat 8 as well as GEDI-derived forest structure data to
address our research questions. We found that disturbances induced
seasonal water stress, more pronounced and earlier in croplands and
pastures than in forests, and more pronounced in second-growth and
recently burned areas than in logged and intact forests. Moreover, we
found that ET and LST were negatively related, with a more consistent
relationship across disturbance classes in the dry season than the wet
season, and that forest and cropland and pasture classes showed
contrasting relationships in the dry season. Finally, we found that
canopy structural properties exhibited moderate relationships with ET
and LST in the most disturbed forests, but negligible correlations in
the least disturbed forests. Our findings help to elucidate degraded
forests functioning under a changing climate and to improve estimates of
water and energy fluxes in the Amazon degraded forests.
Application of Aerial InSAR to Measure Glacier Elevations
Authors: Glenn Bryce , Fountain Andrew G. , Moller Delwyn
Published: March 2023

Glaciers and perennial snowfields are important to alpine ecosystems and
regional hydrology. Quantifying volume change of a population of
glaciers widely distributed over a region is difficult and expensive. We
employed NASA’s novel Airborne Glacier and Ice Surface Topography
Interferometer (GLISTIN) to rapidly map surface topography of alpine
glaciers across the western USA. In five flight days 3289 glaciers and
perennial snowfields were surveyed. Comparison with lidar over control
sites showed a mean difference of +0.17 ±1.78 m at a spatial scale of 3
m. Data coverage increased and elevation uncertainty decreased with the
mosaicking of multiple passes due to the complex terrain. Elevation
change since the National Elevation Dataset shows a thinning (and volume
loss) over the last ~56 years, averaging -0.3 ± 0.2 m
and accelerating since 1980. GLISTIN can be a valuable tool for rapidly
mapping ice surfaces in the alpine environment.
Relación entre el clima organizacional y la competencia docente en escuelas municipales de Talca
Authors: Rojas Oscar , Ortega Francisca , Espinosa Mauricio , Campbell Lucas
Published: March 2023

En la gran mayoría de las organizaciones existe una armonía en el trabajo que es observado y ejercido por todos sus miembros, aspecto que abarca en el concebir y reaccionar de los empleados frente a los acontecimientos que se suscitan, por ello la relevancia de avivar el clima organizacional, donde el líder debe saber hacia dónde puede dirigir y equilibrar los propósitos institucionales. La presente investigación tiene como objetivo general analizar la relación entre el clima organizacional y el docente competitivo de las Escuelas Municipales de Talca, para ello se enmarcó en una investigación básica, no experimental, transeccional, correlacional, descriptiva, la muestra de 58 docentes, la recolección de datos a través de la encuesta y como instrumento, cuestionario con escalamiento Likert. La investigación reveló que existe una relación directa y significativa entre clima organizacional y docente competitivo con un valor de 0.817, también se debe destacar el rechazo de la hipótesis nula, debido a que el valor de significancia es < 0.05 aceptando que las variables tienen relación entre sí, concluyendo que toda institución educativa que desarrolla un clima organizacional excelente basado en la iniciativa, compromiso y la  actuación del personal docente logrará alcanzar la competitividad en las praxis educativa.
Personalization exercise recommendation framework based on knowledge concept graph
Authors: Yan Zhang , Du Hongle , Lin Zhang , Jianhua Zhao
Published: March 2023

With the explosive increase of online learning resources, how to provide students with personalized learning resources and achieve the goal of precise teaching has become a research hotspot in the field of computer-assisted teaching. In personalized learning resource recommendation, exercise recommendation is the most commonly used and most representative research direction, which has attracted the attention of a large number of scholars. Aiming at this, a personalized exercise recommendation framework is proposed in this paper. First, it automatically constructs the relationship matrix between questions and concepts based on students' answering records (abbreviated as Q-matrix). Then based on the Q-matrix and answer records, deep knowledge tracing is used to automatically build the course knowledge graph. Then, based on each student's answer records, Q-matrix and the course knowledge graph, a recommendation algorithm is designed to obtain the knowledge structure diagram of every student. Combined the knowledge structure diagram and constructivist learning theory, get candidate recommended exercises from the exercise bank. Finally, based on their diversity, difficulty, novelty and other characteristics, exercises are filtered and obtain the exercises recommended to students. In the experimental part, the proposed framework is compared with other algorithms on the real data set. The experimental results of the proposed algorithm are close to the current mainstream algorithms without the Q-matrix and curriculum knowledge graph, and the experimental results of some indicators are better than Algorithms exist.
Adouble-blindcomparisonoftwocreamscontainingureaas theactiveingredient. Assessment of efficacy and side-effects by non-invasive techniques and a clinical scoring scheme
Authors: Serup Jørgen
Published: March 2023

From a group of 72 healthy individuals, 47 with evidence of dry skin according to measurements by non-invasive techniques were enrolled for a 3-week study withdouble-blindand randomized treatment of one forearm, using either 3%ureacream (HTH lotion 'light') or 10%ureacream (HTH lotion 'Original'). The contralateral forearm served as an untreated control.Twovolunteers had to be excluded because measurements of skin surface lipids gave evidence of vehicle components on the skin surface at the time of final evaluations. Evaluations took place not less than 12 h after the last application. According to questionnaire replies, thetwocreamswere equally effective. This was confirmed by "blind" evaluation of the skin hydration state by a dermatologist, measurements of electrical capacitance and conductance indicating epidermal and skin surface hydration, and by D-Squame tape assessments including optical transmission of tapes with stratum corneum and scales from adhering skin, as well as visual scoring of the tapes. The methods showed a high degree of correlation, i.a. a definite relation between increase in electrical hydration parameters, reduced scaling according to the D-Squame tape evaluations, and clinical improvement of dryness. In skin treated with 10%ureacream the transepidermal water loss (TEWL) decreased, indicating an improved water barrier function. Skin colour measurement according to the CIE colour system showed that skin treated with the 3%ureacream turned in the direction of yellow, and there was generally a tendency for the brightness to decrease. Thus, the 3%ureacream gave the skin a more golden colour. There was no change in redness with any of thecreams. Neither data from the questionnaire, the clinical examination, nor results of TEWL and colour measurements indicated any local irritant effect ofureacausing water barrier damage or inflammation. In conclusion, the 3% and 10%ureacreamswere both found efficient, resulting in improvement of hydration and reduction of scaling. Both were non-toxic. However, specific differences did appear, viz. the 3%ureacream turned the skin colour golden, while the 10%ureacream improved the skin's water barrier function.
Urea in the treatment of dry skin
Authors: Swanbeck Gunnar
Published: March 2023

Urea is a unique physiological substance. It has frequently been used in dermatological therapy for more than 20 years. The relevant properties of urea with regard to its use in dermatological preparations are discussed in this brief review. Urea's natural presence in the horny layer, its water solubility, dipolar character and relation to concentrated solutions of electrolytes, are highlighted. The clinical use of urea creams is discussed with respect to indications, side-effects and combinations with other substances.
Cementeczema. Anepidemiologicalintervention study.
Authors: Avnstorp Christian
Published: March 2023

No abstract available
Atopic diseases in Norwegian Lapps
Authors: Falk Edvars S.
Published: March 2023

The occurrence of atopic diseases in Lapps was estimated by reviewing medical records in the local health centre of Kautokeino. Atopic diseases were found to be present or to have occurred in 306 (10.4%) of the 2,950 individuals reviewed, with no difference between males (10.6%) and females (10.2%). Atopic diseases were detected more frequently in those under 20 years (19.4%) than in those 20 years or older (5.5%). On average, asthma occurred more frequently in males (4.2%) than in females (2.9%), even more so in the younger age group (males = 7.5%, females = 2.5%). Similarly, the occurrence of allergic rhinoconjunctivitis was remarkably low, but found in more males (2.3%) than in females (1.9%) with the frequency increasing in those under 20 years (males = 4.7%, females = 2.9%). A peak prevalence was observed in the age group 10-19 years (6.1%). On the other hand, atopic urticaria was found more frequently in females (1.0%) than in males (0.3%), whereas atopic dermatitis occurred with the same frequency in females (6.4%) and males (6.1%) followed by the frequency in those under 20 years increasing to 13.9% and 13.5%, respectively.
Prevalence of psoriasis in a Norwegian Lapp population
Authors: Falk Edvard S , Vandbakk Øyvind
Published: March 2023

The occurrence of psoriasis in a Norwegian Lapp population was estimated by reviewing medical records in the local health centre of Kautokeino. Altogether 40 cases of psoriasis were registered in the study population comprising 99.6% of the total population of 2,963 individuals. Thirty-five cases of psoriasis belonged to the Lappish population of 2,508 people, giving a prevalence of 1.4%, with no difference between males and females. Five cases of psoriasis were found in the non-Lappish population of 442 individuals which gives a prevalence of 1.1% with no sex differences. A peak prevalence among Lapps was observed in the age groups 20-39 years (2.7%), equal for both sexes and in females aged 50-59 years (3.2%), whereas a lower prevalence of 0.6% was found in the age group 40-49 years. A seronegative psoriatic arthritis was recorded in 6 of the 35 Lappish compared to none of the non-Lappish cases. A familial association was confirmed in 11 of the 35 Lappish cases, in none of the non-Lappish.
The coexistence of psoriasis with lupus erythematosus and other photosensitive disorders.
Authors: Zalla Mark J. , Muller Sigfrid A.
Published: March 2023

No abstract available
Experimental itch in human skin elicited by rat mast cell chymase
Authors: Hagermark O. , Rajka G. , Bergvist U.
Published: March 2023

No abstract available
Pattern of sweat gland activity on the forearm after pharmacologic stimulation
Authors: Spruit D. , Reynen AT.
Published: March 2023

No abstract available
Electron microscopy of histiocytic diseases of the skin
Authors: Carrington SG. , Winkelmann RK.
Published: March 2023

No abstract available
Pemphigus and thymoma
Authors: Stillman MA. , Baer RL.
Published: March 2023

No abstract available
Atopic winter feet in children
Authors: Möller H.
Published: March 2023

No abstract available
Piezogenic papules of the feet
Authors: Woerdeman MJ. , Van Dijk E.
Published: March 2023

No abstract available
Treatment of polymorphous light eruptions with beta-carotene
Authors: Swanbeck G. , Wennersten G.
Published: March 2023

No abstract available
Wound healing and vitamin A acid
Authors: Prutkin L.
Published: March 2023

No abstract available
Lichen amyloidosus. An unusual clinical variant associated with the Koebner phenomenon
Authors: Black MM.
Published: March 2023

No abstract available
Ultrastructural changes of mitochondria in dithranol-treated psoriatic epidermis
Authors: Swanbeck G. , Lundquist PG.
Published: March 2023

No abstract available
Bacterial Contamination of Surfaces in the Surgical Rooms at AlMak Nimer University Hospital, Shendi Town-Sudan, 2023
Authors: Ali Alhaj Saad Mohamed Ahmed
Published: March 2023

Background: Bacterial Contamination in surfaces at surgical rooms is one of the most life-threatening sources of infection acquired in hospitals for patients. The study was conducted at El-Mak Nimer University Hospital in Shendi town from the beginning of October 2022 to January 2023 to isolate and identification of pathogenic bacteria in the surgical site environment. Material and Methods: 30 Samples were taken by passing a cotton swab on the surfaces in surgical rooms, than incubated in the laboratory, isolated and conducted the necessary tests to identify the types of bacteria. Results: Bacterial contamination was detect as 43.3% in surfaces samples, and pathogenic bacteria were 52%. By typing these pathogens were found: 69.23% Staphylococcus aureus, 23.07% Pseudomonas and 7.7% Klebsiella.
Prioritizing the Implementation of Ghana's National Aging Policy
Authors: Nutakor Jonathan Aseye
Published: March 2023

I’m writing to express my concerns regarding Ghana’s 2010 National Aging Policy’s implementation delay. This policy was designed to tackle the challenges that older people confront in the country, such as poverty, a lack of access to healthcare, and a lack of social support. Despite being adopted over a decade ago, it has failed to be fully implemented, leaving senior Ghanaians with several challenges.
Основы сравнительной педагогики сквозь призму новых социальных измерений: позиция Н. А. Ганца
Authors: Поляков Константин , Пономарева Светлана , Федотова Ольга
Published: March 2023

Статья посвящена проблеме влияния идей представителей русского зарубежья начала и середины ХХ века на становление и развитие педагогической мысли и теории педагогики. Во Введении на примере анализа концепции сравнительной педагогики, предложенной Н. А. Ганцем, показано, что спектр подходов к рассмотрению традиционной компаративной проблематики может быть значительно расширен за счет ее анализа сквозь призму принадлежности педагогов к определенным, в том числе тайным, социальным объединениям. Новизна заключается в представлении, в логике подхода Н. А. Ганца, проблемы педагогической компаративистики к оценке принадлежности педагогов к масонству. Методы включают обоснование выбора в качестве эмпирического источника программной работы Н. А. Ганца по сравнительной педагогике. Методы исследования включали контент-анализ, сравнительный анализ, кластерный анализ, интерпретация, генерализация. В разделе «Результаты» приведены данные контент-аналитических исследований, отражающие частотность обращения Н. А. Ганца к теоретическому наследию лиц, причисляемых им к числу авторов-масонов. В разделе «Обсуждение результатов» дан анализ вклада лиц, педагогическая деятельность которых связана с идеями братских объединений, идеологией космополитизма и всемирного гражданства. Подробно анализируется один из кластеров, объединяющих педагогов различных типологических групп, в который включены Я. А. Коменский и И. Г. Фихте. Излагаются и оцениваются аргументы и позиция Н. А. Ганца относительно влияния их педагогических концепций на теорию и практику обучения и воспитания. На основе разбора педагогического наследия данных авторов, представленного их произведениями, хорошо известным российским исследователям, показано, что возможны два пути влияния масонских идей на их приверженцев. Первый из них делает возможным трансформацию системы педагогических воззрений от идеи воспитания национальной идентичности к идеям ее утраты и популяризации идеала гражданина мира (Я. А. Коменский), второй – от идей космополитизма к формированию идеи национального превосходства (И. Г. Фихте). Заключение отражает важнейшие результаты исследования.
PENGARUH INTENSITAS MODAL, PERTUMBUHAN PENJUALAN DAN UKURAN PERUSAHAAN TERHADAP PENGHINDARAN PAJAK
Authors: Marta Desviya , Nofryanti Nofryanti
Published: March 2023

This study aims to determine the effect of capital intensity, sales growth and company size on tax avoidance in healthcare companies listed on the indonesia stock exchange. This type  of research is type of quantitative research. The data used in this study is secondary from the indonesia stock exchange for the period 2016-2020. The number of samples in this study were 8 companies with an observation period of 5 years so that the number of research samples is 40.. The technic used in this research is purposive sampling. The data in this study used panel data regression analysis using the Eviews 12 application. Based on the results of panel data regression analysis, it show that capital intensity have no effect on tax avoidance, sales growth and company size an effect on tax avoidance.
KEBIJAKAN PENGECUALIAN PAJAK DIVIDEN: KABAR BAIK ATAU BURUK BAGI INVESTOR
Authors: Shofiyah Indah , Mirza. BR Aryan Danil , Saryadi Turnip Cornelius , Nani  Djismudin Ayu , Razif Afero Raihan , Maulana Nasrul
Published: March 2023

The issuance of Omnibus Law Policy is predicted to be an effective policy in simplifying regulations, especially in the field of taxation. This study aims to find out in depth the perceptions of various parties regarding the implementation of PMK No. 18 regarding Exceptions from the Imposition of Income Tax on Dividends. Researchers try to map the problem from various perspectives, including investors, securities companies, tax consultants, tax officials and academics. The research was conducted using a qualitative approach with structured interview techniques. The results show that this Exemption of Dividend Tax policy is beneficial for corporate taxpayers, while for personal taxpayers it still tends to be detrimental because the administration is too complicated. So that policy makers need to review the implementation of Minister of Finance Regulation. In addition, the results of the study also show that although in the short term this policy has the potential to reduce Government revenues from the tax sector, in the long term this policy has the potential to accelerate national economic growth, especially after the Covid-19 pandemic. This research can be a reference for the government and academics in implementing policies in the field of taxation.
The Effects of Job Insecurity on Turnover Intention of Stars Hotel Employee in DKI Jakarta: Mediating Role of Job Stress
Authors: Putri Widya A. , Ariyanto Eny
Published: March 2023

The hotel industry is in a state of perpetual change due to the emergence of covid-19, high competition, and the economic crisis. Based on that situation, this research study discusses the effects of Job Insecurity and Job Stress on Turnover Intention and also the mediating role of Job Stress. A total of 150 surveys were conducted in stars hotel in DKI Jakarta by adapting non-probability sample using purposive sampling technique. This research study was used the Structural Equation Model and processed with Structural Positive and Equation Model (SEM) Partial Least Square (Smart PLS) software to test the hypotheses in a mediation model with the bootstrapping method. The result presents that job insecurity was insignificant toward turnover intention while job stress was positive and significant toward turnover intention, job insecurity was positive and significant toward job stress, and mediating relationship was also confirmed.
DINAMIKA HARGA MINYAK GORENG SERTA DAMPAKNYA TERHADAP PENGUKURAN STANDAR KUALITAS PRODUK
Authors: Andriana Ana Noor , Wulandari Chofifah
Published: March 2023

Penelitian ini bertujuan untuk menggambarkan dinamika perubahan harga minyak goreng dalam sektor industri serta dampaknya terhadap pengukuran standar kualitas produk pada usaha kuliner. Data penelitian ini dikumpulkan berdasarkan hasil wawancara, observasi dan pengumpulan dokumen. Penelitian ini berjenis kualitatif dengan pendekatan studi kasus. Analisis data dilakukan dengan tiga tahapan yang dimulai dari reduksi data, data display dan selanjutnya penarikan kesimpulan. Penelitian ini memberikan bukti empiris serta pengukuran standar kualitas produk dari usaha kuliner dengan menggunakan alur proses produksi yang optimal yang digunakan untuk meminimalisir kecacatan dan kerusakan produk. Permasalahan terkait kualitas produk juga ditentukan oleh biaya dan pemenuhan persedian bahan baku serta proses produksi lainnya. Pengukuran standar kualitas produk ini meliputi input-proses-output dengan menyelesaikan setiap permasalahan salah satunya yaitu perubahan harga bahan minyak goreng yang terjadi selama Pandemi Covid-19. Hasil penelitian dapat menjadi referensi terkait pengendalian kualitas pada proses produksi yang dilakukan dari pra produksi dan pasca produksi dengan harapan dapat lebih mudah menyelesaikan permasalahan dengan cepat dan meninimalisir kesalahan dalam kegiatan produksi.
PERAN PENDIDIKAN NONFORMAL DALAM PEMBINAAN MENTAL SPIRITUAL PESERTA KELOMPOK BELAJAR AL AMANAH PALANGKA RAYA
Authors: Darlan Saifullah
Published: March 2023

Learning can be done anytime and anywhere, learning does not need to have an age limit. As has been done by the participants of the Al Amanah Palangka Raya study group, which consists of adults and the elderly, aged between 20 to 80 years. Their education and occupation levels vary, ranging from civil servants, retirees, drivers, and laborers. It is intended that this study group has the knowledge, mental spirituality, and strong character so that their lives are calm and they can move well. This research method uses a participatory qualitative approach, with observation techniques, in-depth interviews, and documentation. Data analysis starts from data collection, data condensation, data display, and conclusion and verification. The results showed that, First, the implementation of learning applies adult learning patterns with a family atmosphere, sharing knowledge and respecting each other's opinions. Second, the level of participation of study group participants in following learning is very good. Third, after participating in the learning there are changes in the attitudes and behavior of group members in interacting in the community.