bluuebunny/crossref_metadata_2025 huggingface dataset:
Regional Block, Wound Infiltration, and Caudal Block For Post Operative Pain Management in Children Undergoing Inguinal Herniotomy: A Randomized Controlled Trial
Authors: Asmati Mamoonullah , Naumeri Fatima , Janjua Azwa , Khan Muhammad Shakeel
Published: July 2024

Background: Pain management postoperatively for such a common condition plays an important role, as unmanaged pain may cause behavioral and sleep changes, and parental distress.
Objective: To compare regional block, caudal block, and wound infiltration for post-operative pain management in pediatric inguinal herniotomy.
Methods
A randomized, controlled trial (NCT 05969613) was carried out in pediatric surgery department, KEMU from January till December 2019, and 300 patients undergoing inguinal herniotomy were enrolled after informed consent. They were randomly allocated in 3 groups and underwent regional block in Group A, wound infiltration in Group B, and caudal block in Group C using Bupivacaine. Rescue analgesia was given if pain scores were ≥4. Postoperative pain scores, duration of analgesia and complications like urinary retention and wound infection were compared.
Results: Postoperative FLACC scores revealed need of rescue analgesia in 9(9%) patients at 2nd hour in Group C (p value <0.001), and at 8th hour, 12(12%) in Group A, 19(19%) in Group B, and 30(30%) in Group C had score ≥4 (p value 0.000). Wong Baker Score also revealed higher scores and need of rescue analgesia in Group C than Group A or B after 4 hours postoperatively (p value <0.001). Duration of analgesia was 288.16±23.7 min in Group A, 338.55±19.79 min in Group B, and 262.43±15.4 min in Group C (p value <0.001). Urinary retention was present in 9 (9%) children in Group C (p value <0.001). Six (6%) children had wound infection in Group A, three (3%) in Group B, and 15 (15%) in Group C (p value 0.005).
Conclusion: Regional block and wound infiltration were more effective as compared to caudal block in terms of pain control. Caudal block also had more complication rates.
Uso de la tecnología en la educación universitaria exploración bibliométrica
Authors: Navarro-Castillo Yulissa , Ugaz Mildher
Published: July 2024

The aim of this article is to scrutinize the advancement and significance of technology utilization in higher education, with the purpose of comprehending present trends and identifying novel avenues of inquiry that are of significance to the academic community. A quantitative approach was employed by conducting a bibliometric analysis on 43 scientific articles retrieved from the Scopus database, in order to obtain the most pertinent metrics of high-impact publications that were produced up until 2023. The research findings regarding the implementation and use of technology at the university level are very dispersed and underdeveloped, with the most relevant topics being motivation and the human factor in learning with technologies. Furthermore, a concentration of articles was found in four countries and in 31% of scientific journals. This study is unique because it applies a methodology enhanced with the use of a digital tool for a level that is underserved in terms of research and education at the university level.
New Insights in Psoriasis Management using Herbal Drug Nanocarriers
Authors: Salgaonkar Shreyas P. , Purewal Japneet Singh , Doshi Gaurav Mahesh , Fernandes Trinette , Gharat Sankalp , Sawarkar Sujata P.
Published: July 2024

Psoriasis (Pso) is an autoimmune inflammatory skin disease characterized by red plaques covered
in silver scales. The existing treatments provide limited benefits and are associated with certain drawbacks
which limit their use. Thus, there is a need to explore more options that are highly target-specific and associated
with minimal side effects. Researchers have thoroughly investigated the use of herbal drugs for their therapeutic
potential. Preclinical studies demonstrate that phytochemicals such as curcumin, psoralen, and dithranol
have antipsoriatic effects. These phytoconstituents inhibit the signalling pathways, such as the interleukin (IL)
23/Th17 axis and IL-36 inflammatory loop involved in the pathogenesis of Pso. These phytoconstituents
down-regulate the pro-inflammatory cytokines like IL-17 and tumor necrosis factor (TNF)-α. However, their
application in clinical settings is limited due to poor bioavailability and access to target sites. Combining phytoconstituents
with modern delivery platforms like nanocarriers can address these shortcomings and improve
therapeutic efficacy. This review explores the potential of herbal remedies as a substitute for conventional therapies,
emphasizing the clinical trials conducted with these herbal medicines. The paper is supported by the discussion
on nanocarriers like liposomes, niosomes, emulsomes, ethosomes, nanostructured lipid carriers, nanoemulsions,
and dendrimers that are used to deliver herbal medicines.
Influence of Seamless Patient-Centered Care on Efficiency, Satisfaction, and Patient Awareness in Imaging Departments: A Prospective Cohort Study
Authors: Yan Shouzhen , Luo Xiaohua , Xia Qianzhi , Luo Shijie , Xu Feng
Published: July 2024

Aims:

This study aimed to enhance the existing nursing model in imaging departments by implementing a characteristic seamless nursing care approach
and assessing its impact on patient and medical staff satisfaction, nursing quality, examination efficiency, and patient awareness. We hypothesized
that the implementation of a seamless nursing care model would be associated with higher patient satisfaction, improved nursing quality, increased
examination efficiency, and better patient awareness compared to the traditional nursing model.

Materials and Methods:

This prospective cohort study included 300 patients undergoing imaging examinations from January 2019 to January 2022. Subjects were divided
into control and observation groups (n=150 each) based on different nursing methods. The control group received routine care, and the observation
group received seamless care. The following outcome measures were assessed using validated questionnaires: patient satisfaction (measured using
a 5-point Likert scale), medical staff satisfaction with patient examination cooperation (measured using a 5-point Likert scale), nursing quality
compliance rate (percentage of nursing tasks performed according to established guidelines), dissatisfaction rate (percentage expressing
dissatisfaction with examination cooperation), and effect evaluation [measured using a knowledge test validated in previous studies (Chung et al.,
2020) with a total score range of 0-20].

Results:

Average imaging examination and nursing times were significantly lower in the observation group compared to the control group (P<0.05). The
examination cooperation dissatisfaction rate was significantly lower in the observation group (P<0.05). There were significant differences in
examination precautions, procedures, breathing training methods, and injection comparisons between the groups (all P<0.05).

Conclusion:

The application of seamless nursing care may be associated with improved patient satisfaction, nursing service quality, imaging examination
efficiency, and patient awareness of imaging examinations. However, further research is needed to establish causal relationships
Isolation and Characterization of Cytotoxic Compounds from Detarium microcarpum Guill. and Perr. Stem Bark
Authors: Salawu Kayode Muritala , Ogbole Omonike Oluyemisi , Abiodun Oyindamola Oduola , Wang Yan
Published: July 2024

Introduction:

Globally, about 8.2 million cancer-related deaths are recorded annually. Sadly, most of
the deaths result from the toxicity of most chemotherapeutic agents. Hence, there are growing demands for
chemotherapeutic agents with high specificity and selectivity. This study was designed to assess the cytotoxic
potential of Detarium microcarpum and isolate cytotoxic compounds with better selectivity profiles.

Methods:

Detarium microcarpum Stem bark (DMS) was collected and authenticated at the Forest Herbarium
Ibadan (FHI), and a voucher (FHI-111954) was issued. Dried DMS was pulverized and extracted into 70% methanol.
The extract was partitioned into hexane, dichloromethane, and ethyl acetate fractions. The cytotoxicities of
the extract, fractions, and isolated compounds were determined. The cytotoxicity of the isolated compounds was
tested against different cell lines, including human breast (AU565 and MDA MB231), oral adenosquamous
(CAL27), and cervical (HeLa) cancer cells, as well as healthy (3T3) non-cancer cells.

Results:

Methyl gallate, eriodictyol, quercetin, quebrachitol, catechin, catechin gallate, and gallic acid, isolated
from dichloromethane and ethyl acetate fractions, displayed weak cytotoxicity against breast (AU565 and MDAMD-
231) and cervical (HeLa) cancer cell lines. Interestingly, all the compounds, except gallic acid (48.91±4.51%
inhibition), displayed potent cytotoxicity on oral cancer cells. Methyl gallate and quercetin displayed the highest
activity, with IC50 values of 89.57±1.98μM and 78.19±1.49μM, respectively. Interestingly, all the compounds
were not toxic to healthy non-cancer (3T3) cells.

Conclusion:

The compounds displayed anticancer activity specific to oral cancer cells and were highly selective
for cancer cells without causing significant toxicity to healthy non-cancer cells.
Association of Pesticides with Adolescent Asthma and Bronchial Hyper-Reactivity
Authors: Singh Shivani , Verma Juhi , Tiwari Vandana , Kulshrestha Manish Raj
Published: July 2024

Lung exposure to airborne toxins from various sources in the environment
can lead to acute and chronic pulmonary or even systemic inflammation. The
environment contains several compounds that might irritate the respiratory system,
including heavy metals and agrochemicals in adolescents. Toxicants can induce
respiratory illnesses and airway inflammation, which alters either the structure,
function, or composition of the body. Because of their long-term physical development,
the developing immune and respiratory systems are particularly vulnerable to various
environmental toxins. They promote the accumulation and activation of several allergy
indicators (eosinophil count, IgE, and numerous cytokines), which may be used to
potentially trigger lung inflammation. This chapter describes the impact of various
toxic substances on the airway and pulmonary system. Also, we have covered specific
pulmonary toxins, toxicants, and toxin combinations. The concluding section of the
chapter emphasizes raising awareness of the dangers and adverse effects toxicants may
have on health as well as encouraging more efforts to reduce exposure to adolescents.
Metropolitan residents use pesticides for the prevention of mosquitoes, ticks, ants, and
cockroaches. Reducing indoor allergens and pollution can lower asthma treatment costs
and severity.
Exploring How Older Adults Experience semAPP, a 360° Media–Based Tool for Memory Assessment: Qualitative Study
Authors: Bruni Francesca , Mancuso Valentina , Panigada Jonathan , Stramba-Badiale Marco , Cipresso Pietro , Pedroli Elisa
Published: July 2024

Background

Technology is already a part of our daily lives, and its influence is growing rapidly. This evolution has not spared the health care field. Nowadays, a crucial challenge is considering aspects such as design, development, and implementation, highlighting their functionality, ease of use, compatibility, performance, and safety when a new technological tool is developed. As noted in many works, the abandonment rate is usually higher when a user has a terrible experience with these instruments. It would be appropriate to incorporate the final users—whether they are patients, health care professionals, or both—in the stages of instrument design to understand their needs and preferences. Since most apps that fail did not include end users and health care professionals in the development phase, their involvement at all stages of app development may increase their commitment and improve integration, self-management, and health outcomes.

Objective

This study aims (1) to develop semAPP (spatial and episodic memory assessment application), a 360° media–based tool, to assess memory in aging by simulating a real-life situation and (2) to test the usability of the app and the connected experience in an end-user population.

Methods

A total of 34 older adults participated in the study: 16 (47%) healthy individuals and 18 (53%) patients with mild cognitive impairment. They used semAPP and completed qualitative and quantitative measures. The app includes 2 parts: object recognition and spatial memory tasks. During the first task, users have to navigate in an apartment freely and visit rooms, and then they must recognize the right map of the house. In the second task, users are immersed in a living room, and they have to encode and then recall some target objects, simulating a relocation. We deployed this app on an 11.2-inch iPad, and we tested its usability and the experience of users interacting with the app. We conducted descriptive analyses for both the entire sample and each subgroup; we also conducted parametric and correlation analyses to compare groups and to examine the relationship between task execution and the virtual experience, as well as the acceptance of technology.

Results

Both groups judged the app as an easy-to-use tool, and they were willing to use it. Moreover, the results match the idea that usability might be influenced by different factors depending on instrument and personal features, such as presentation, functionality, system performance, interactive behavior, attitudes, skills, and personality.

Conclusions

The findings support the possibility of using semAPP in older patients, as well as the importance of designing and evaluating new technological tools, considering not only the general population but also the specific target ones.
Hjernetegn.dk—The Danish Central Nervous System Tumor Awareness Initiative Digital Decision Support Tool: Design and Implementation Report
Authors: Weile Kathrine Synne , Mathiasen René , Winther Jeanette Falck , Hasle Henrik , Henriksen Louise Tram
Published: July 2024

Background

Childhood tumors in the central nervous system (CNS) have longer diagnostic delays than other pediatric tumors. Vague presenting symptoms pose a challenge in the diagnostic process; it has been indicated that patients and parents may be hesitant to seek help, and health care professionals (HCPs) may lack awareness and knowledge about clinical presentation. To raise awareness among HCPs, the Danish CNS tumor awareness initiative hjernetegn.dk was launched.

Objective

This study aims to present the learnings from designing and implementing a decision support tool for HCPs to reduce diagnostic delay in childhood CNS tumors. The aims also include decisions regarding strategies for dissemination and use of social media, and an evaluation of the digital impact 6 months after launch.

Methods

The phases of developing and implementing the tool include participatory co-creation workshops, designing the website and digital platforms, and implementing a press and media strategy. The digital impact of hjernetegn.dk was evaluated through website analytics and social media engagement.

Implementation (Results)

hjernetegn.dk was launched in August 2023. The results after 6 months exceeded key performance indicators. The analysis showed a high number of website visitors and engagement, with a plateau reached 3 months after the initial launch. The LinkedIn campaign and Google Search strategy also generated a high number of impressions and clicks.

Conclusions

The findings suggest that the initiative has been successfully integrated, raising awareness and providing a valuable tool for HCPs in diagnosing childhood CNS tumors. The study highlights the importance of interdisciplinary collaboration, co-creation, and ongoing community management, as well as broad dissemination strategies when introducing a digital support tool.
Navigating Communication Challenges in using English as a Lingua Franca: The Stories of Indonesian Students in Australia
Authors: Kurniawan Hasyim
Published: July 2024

This research explores intercultural communication encountered by Indonesian students studying in Australia, where English serves as the lingua franca. Employing the narrative accounts of participants as a valuable source of qualitative data, this research aims to identify the distinct categories of understanding-related problems experienced by Indonesian students when engaging with non-native speakers of English and to explain the strategies employed in managing such challenges. Additionally, an evaluation of the efficacy of English language teaching and learning in Indonesia is conducted to ascertain its role in mitigating understanding issues. Data for this study were gathered through open-ended interviews conducted with eight Indonesian students enrolled in master's programs at Monash University, Australia. The findings reveal that students encounter three levels of understanding problems: 1) non-understanding, 2) partial understanding, and 3) misunderstanding. The analysis underscores two predominant strategies employed by students in managing these challenges: 1) signaling the problem and 2) allowing it to pass without clarification. Furthermore, the research reveals that although participants find their English studies effective in academic contexts like class discussions and written tests, they feel that their acquired language skills lack adequate guidance for daily interactions in Australia. The study proposes specific improvements in English language teaching (ELT) in Indonesia to better equip students for the diverse linguistic challenges in intercultural settings by incorporating three competences namely interactional competence, strategic competence and multidialectal competence.
Pompas fúnebres
Authors: Hiriart Hugo
Published: July 2024

La obra Pompas fúnebres es el discurso de Ingreso a la Academia Mexicana de la Lengua del escritor Hugo Hiriart. Es una extraordinaria disertación sobre el tema de la muerte.
UNAM. L’université de la nation
Authors: Trigo Tavera Francisco José
Published: July 2024

Versión en francés de UNAM. La universidad de la nación, obra en la que se hace un recuento puntual y actualizado de la presencia y los alcances de la Universidad Nacional Autónoma de México en los ámbitos nacional e internacional. En sus páginas se da testimonio de las principales actividades cotidianas en investigación, docencia y difusión de la cultura y se refleja el compromiso adquirido con la sociedad mexicana, con la formación de un capital humano libre y responsable, y con los logros y desafíos que han beneficiado a la comunidad.
Un posgrado es una satisfacción personal
Authors: Hernández García Jorge Gihovani
Published: July 2024

La vida universitaria de Jorge Hernández comenzó en el CCH Oriente, para luego continuar en la Facultad de Ciencias Políticas y Sociales de la UNAM en donde terminó una Licenciatura en Ciencias Políticas y Administración Pública con una tesis, cuya línea de investigación lo llevó a interesarse en cursar un Posgrado en Derecho con una Maestría en Política Criminal, un logro que se vio recompensado con la Medalla Alfonso Caso 2019.
Mapas geológico, morfoestructural y de tipología volcánica de la región de Morelia
Authors: Robles Pereznegrón Miranda , Corona-Chávez Pedro
Published: July 2024

Se presentan los mapas geológico, morfoestructural y de tipología volcánica de la región de Morelia (2,858 km2 ) escala 1:60,000. Todas las unidades litoestratigráficas y volcánicas previamente definidas han sido revisadas y nuevamente mapeadas a partir de una extensa revisión bibliográfica, modelos digitales de elevación LiDAR, ortofotos escala 1:50,000, imágenes Spot 6, así como la verificación en campo de los contactos, distribución espacial y relaciones estratigráficas. Se identificaron y clasificaron 216 tipologías volcánicas, las cuales fueron proyectadas en el mapa morfoestructural que contiene a su vez 18 dominios que ponen en evidencia la importancia de los procesos tectónicos asociados con el vulcanismo. Se agrupan 20 unidades geológicas en seis grandes etapas geológicas y un hiatus magmático, desde el Oligoceno al Holoceno (30 Ma – 3.2 ka). Con base en la cartografía geológica, se plantea su importancia para el manejo sustentable de las Áreas Naturales Protegidas y de las problemáticas geológico-ambientales de la región de Morelia. Se concluye que la cartografía geológica y morfoestructural representa una potente herramienta para delinear a futuro estrategias de geoconservación como una alternativa para el manejo del territorio de la región de Morelia.
Los derechos a la naturaleza como una expresión de reconocimiento a las cosmovisiones indígenas: casos de Ecuador y Bolivia
Authors: Casanova López Judy Vanessa
Published: July 2024

Conceder derechos a la naturaleza puede ser interpretado de diversas maneras. Por un lado, podría considerarse como un medio para demostrar la historicidad y relatividad de los derechos, apuntando a la expansión de los sujetos que abarcan. Por otro lado, también se podría ver como una reivindicación de las cosmovisiones indígenas ancestrales, las cuales fueron marginadas en el afán homogeneizador de Occidente. Incluso se podría argumentar que es simplemente una estrategia mediante la cual el modelo económico y social actual busca su supervivencia. En cualquier caso, es innegable la ruptura que representa para la teoría jurídica tradicional la inclusión y denominación de la Pachamama en Ecuador y la Madre Tierra en Bolivia como sujeto de derecho, resaltando que este cambio implica reconocer la importancia de los valores y la cultura de las sociedades en este proceso.
A Single-Lead Electrocardiogram-Derivative Empirical Mode Decomposition-Based Deep Learning Model for Sleep Apnea Identification
Authors: Sree R. Krithiga
Published: July 2024

Abstract: While polysomnography (PSG) is the gold standard for detecting sleep apnea (SA), the insertion of several disruptive devices may impair the quality of the patient's sleep, and its interpretation requires specialised training from a sleep scientist or technician. Heart rate variability (HRV) and electrocardiogram (ECG)-derived respiration (EDR) have been used in recent years to automatically detect SA and lessen the negative effects of PSG. Currently, the majority of suggested methods concentrate on feature engineering and machine learning (ML) techniques, which call for previous expert knowledge and expertise. This paper uses a deep learning (DL) framework based on 1D and 2D deep CNN with empirical mode decomposition (EMD) of a preprocessed ECG signal to propose a SA detection method to distinguish between a normal and apnea occurrence. The EMD is the perfect tool for removing crucial elements that characterise the underlying physiological or biological processes. Based on 5- fold cross-validation (5fold-CV), the segment-level classification performance had 93.8% accuracy with 94.9% sensitivity and 92.7% specificity. As a result, this work effectively created a unique and reliable SA detection system based on the ECG decomposed signal utilising EMD and deep CNN.
From Svyatoslav I to Ivan IV: milestones of gaining rulership in the mythopoeic images of the “Kazan History”
Authors: Aksanov Anvar V. ,   Marjani Institute of History of the Tatarstan Academy of Sciences,   Tyumen State University
Published: July 2024

The purpose of the study: To study the stages of the acquisitions of the Orthodox kingdom in the narrative of the author of the “Kazan History”. Research materials: Historiographical sources, Russian chronicles, historical writings, diplomatic documents, etc. Results and scientific novelty: Previously, researchers have already addressed the problem of studying the concept of gaining the kingdom, presented in the “Kazan History”. It was found that the author of the “Kazan History” compared the capture of Kazan in 1552 with the conquest of Constantinople in 1453. Through this ideological parallel, the chronicler tried to show that the capture of Kazan became a key and final milestone in the struggle of the Rurik Dynasty for the acquisition of the larger kingdom. The history of the conquest of the Kazan Khanate and the associated idea of the liberation of Russia from Tatar domination was also considered. However, the researchers ignored the pre-Horde period of the struggle for the royal regalia and the problem of its correlation with the idea of gaining the kingdom through the capture of Kazan. As a result of this study, it was found that the concept of gaining the kingdom also had a pre-Ordinal component semantically related to the conquest of the “Kazan Khanate through Constantinople” plots. The mythopoeic comparison of Kazan with Constantinople allowed the chronicler to make Prince Svyatoslav Igorevich, who achieved great victories over the Greeks, the founder of the struggle for the kingdom. The victories of Svyatoslav I and Vladimir I became the foundation for the acquisition of the royal crown by Vladimir Monomakh. Similarly, the activities of Ivan III and Vasily III led to the capture of Kazan and the new acquisition of the kingdom by Ivan IV.
Development of internal auditing in Fiji: An institutional theory approach
Authors: Prasad Vishwa Hamendra , Sharma Nileshni Lata , Prakash Shoma
Published: July 2024

The significant area of research is internal audit (IA) and the characteristics of the functions in Fijian organizations. This paper examines how institutional norms determine attributes of IA practices. The authors employed qualitative and quantitative research approaches based on interview evidence, questionnaires, and archival sources. This study theorizes the development of IA practices from an institutional change perspective. Nath et al. (2021) studied the dynamics of the Office of the Auditor General (OAG) of Fiji and their findings show that OAG maintained stabilty. The findings indicate that regulation-based institutional norms explain the adoption of IA and the function’s characteristics in Fijian organizations. This research contributes to understanding key drivers of institutional change that initiate new institutional norms that foster the development of IA by introducing and diffusing new audit practices as old ones deinstitutionalize.
Postmemory of trauma as transgenerational еmpathy: Remembering the Santa pain in Pontic dialogical singing
Authors: Tsekouras Ioannis
Published: July 2024

This article examines the relation between music and the transgenerational
trauma of the Pontic Greeks - the descendants of the 1923 Black Sea
[Karadeniz] refugees. More specifically, the article concerns the 1921
destruction of the Santa locality, in G?m??hane province, and how the memory
of this violence is negotiated in the practice of dialogical and
participatory singing called parakathi or muhabeti. It is demonstrated how
muhabeti enables Pontians to cultivate an empathic postmemory of the 1920s
refugees? Santa trauma and what this might mean for trauma theory in
general.
The funeral laments (pohrebné place) of the Slovak community in Serbia
Authors: Lomen Kristina
Published: July 2024

This study discusses the funeral laments (pohrebn? place or pohrebn?
nariekanie in Slovak) of the Slovak ethnic minority in Srem, Vojvodina,
Repub?lic of Serbia. Among the Vojvodina Slovaks, funeral laments are
gradually becoming extinct, although they could still be heard during the
funeral rites of this ethnicity in various localities of Vojvodina in the
latter half of the twentieth century. This study summarizes the state of the
research on this issue. It focuses on the funeral laments documented by the
author during her field research in Star? Pazova/Stara Pazova, Srem, in
2014.
A multi-attribute decision-making context for hospital site evaluation using distance measures under complex picture fuzzy soft set environment
Authors: Asghar Ali , Khan Khuram , Rahman Atiqe
Published: July 2024

In scenarios containing complex or high-dimensional data, in which conventional distance measures might not be able to accurately portray the subtleties of information interactions, a complex picture fuzzy soft distance measure is crucial. The potential of complex picture fuzzy soft distance measures to manage intricacy, imperfection, and uncertainty across a range of domains is what makes them significant. This article proposes a distance formula based on complex picture fuzzy soft sets (CPiFSs) along with related results in its first phase. Following that, the second phase presents the ?-equalities for the proposed distances of CPiFSs. Establishing a hospital is complicated, especially when it comes to choosing the ideal site because it affects mobility and the efficacy of community service. Even though there are several algorithms in the literature those deals with these location-related decision-making challenges, every algorithm has intrinsic flaws that affect how decisions are made. To overcome these challenges, an algorithm based on CPiFS distance measures is presented in the third phase for the evaluation of hospital sites. Finally, the paper concludes by emphasizing the significance of this research and its potential applications in various contexts.
Tackling Professorial Expert Bias: The Role of ChatGPT in Simplifying Financial Accounting Exam Texts
Authors: Voshaar Johannes , Wecks Janik Ole , Plate Benedikt J. , Zimmermann Jochen
Published: July 2024

Experts tend to produce complex texts but mistakenly consider them an easy read for their audience. Accounting professors likely exhibit such expert bias in formulating exams. Consequently, students struggle with comprehension, giving rise to high failure rates and a shortage of talent for the profession. This study explores the potential of ChatGPT for overcoming expert bias and improving financial accounting exam texts to increase comprehension and performance and reduce frustration and confusion. We ask three key questions: (1) Does text modification with ChatGPT lead to increased perceived comprehension?, (2) Does text modification with ChatGPT result in better performance?, and (3) Does perceived comprehension mediate the relationship between ChatGPT-based text modification and performance? We find that students benefit from ChatGPT-based modification through increased perceived comprehension and reduced confusion and frustration. Causal mediation analysis suggests that improved perceived comprehension attributes significantly to exam performance, but we cannot document an overall positive effect.

JEL Classifications: A2; A22; M4; M41; I23.
Glucagon Clearance Is Decreased in Chronic Kidney Disease but Preserved in Liver Cirrhosis
Authors: Grøndahl Magnus F.G. , Lange Andreas H. , Suppli Malte P. , Bagger Jonatan I. , Thing Mira , Gluud Lise L. , Kofod Dea H. , Hornum Mads , van Hall Gerrit , Trammell Samuel A.J. , Grevengoed Trisha J. , Hartmann Bolette , Holst Jens J. , Vilsbøll Tina , Christensen Mikkel B. , Lund Asger B. , Knop Filip K.
Published: July 2024

It is not completely clear which organs are responsible for glucagon elimination in humans, and disturbances in the elimination of glucagon could contribute to the hyperglucagonemia observed in chronic liver disease and chronic kidney disease (CKD). Here, we evaluated kinetics and metabolic effects of exogenous glucagon in individuals with stage 4 CKD (n = 16), individuals with Child-Pugh A–C cirrhosis (n = 16), and matched control individuals (n = 16), before, during, and after a 60-min glucagon infusion (4 ng/kg/min). Individuals with CKD exhibited a significantly lower mean metabolic clearance rate of glucagon (14.0 [95% CI 12.2;15.7] mL/kg/min) compared with both individuals with cirrhosis (19.7 [18.1;21.3] mL/kg/min, P < 0.001) and control individuals (20.4 [18.1;22.7] mL/kg/min, P < 0.001). Glucagon half-life was significantly prolonged in the CKD group (7.5 [6.9;8.2] min) compared with individuals with cirrhosis (5.7 [5.2;6.3] min, P = 0.002) and control individuals (5.7 [5.2;6.3] min, P < 0.001). No difference in the effects of exogenous glucagon on plasma glucose, amino acids, or triglycerides was observed between groups. In conclusion, CKD, but not liver cirrhosis, leads to a significant reduction in glucagon clearance, supporting the kidneys as a primary site for human glucagon elimination.

Article Highlights
Adaptive Streetscape Architecture of Local Business Neighborhood in Jalan Jendral Urip Sumoharjo
Authors: Herlian Erwin , Aji Fauzi Mizan Prabowo
Published: July 2024

Jalan Jendral Urip Sumoharjo in Surakarta is an example of a street in a big city in Indonesia that has adapted in terms of its streetscape architecture. This adaptation is influenced by many factors and possibilities that need to be explored in the future. One of the dominant determining factors is the discovery of facts about local business development in carrying out trading activities on this road section. This research explores forms of streetscape architectural adaptation in the context of the local business environment, with a focus on Jalan Jendral Urip Sumoharjo. The study explored the unique characteristics of the streetscape, emphasizing its role in responding to a dynamic local business community. The adaptive nature of streetscape architecture is observed by considering factors such as design, functionality, and its integration with local businesses. Jalan Jendral Urip Sumoharjo serves as a specific case study, showcasing the intersection between adaptive urban design and the vitality of the local business environment. Adaptation to the streetscape in terms of architecture is influenced by user needs, in this case the majority of traders who need flexibility.
Building a Foundation for Global Competence: Improving English Language Instruction in Indonesian Curriculum
Authors: Setiawati Yulis
Published: July 2024

The study intends to examine (1) curriculum planning for English study programs, (2) the English language curriculum's structure, (3) how the English language curriculum is put into practice to raise the caliber of graduates, and (4) other related topics. (5) To determine the encouraging and discouraging variables. To evaluate the English learning curriculum. The research technique uses qualitative methods to characterize study site activities, gather data through interviews, observations, and documentation, and evaluate planning and implementation to improve English study program graduates' achievement. research output (1) Students can work out issues with learning English (2) can produce findings regarding the topic of learning English (3) To study English, students can plan, manage, analyze, and apply themselves (4) The ability to speak and understand English is essential for the growth of the curriculum in Indonesia since it opens doors to worldwide communication and boosts one's ability to compete. This article emphasizes the significance of English in Indonesian curriculum and offers tips for successful integration. It aims to develop a curriculum that promotes linguistic proficiency, cultural sensitivity, and global competence by assessing advantages and difficulties.
Apakah Self Confidence dan Maharah Al-Kalam memiliki Korelasi?
Authors: Imelda Murti Ayu , Rahmah Yulia
Published: July 2024

Perbedaan latar belakang sekolah mahasiswa cenderung mempengaruhi self confidence terhadap kompetensi mereka. Kompetensi yang dimiliki mahasiswa dapat mempengaruhi tingkat Self confidence. Self confidence merupakan salah satu penunjang dalam meningkatan keterampilan mahasiswa, khususnya untuk kemampuan maharah al-kalam mahasiswa. Tujuan penelitian adalah mengetahui tingkat self confidence, tingkat maharah al-kalam, dan hubungan antara self confidence dengan maharah al-kalam mahasiswa program studi pendidikan bahasa Arab. Pendekatan pada penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian korelasi. Variabel dalam penelitian ini adalah self confidence (X) dan maharah al-kalam (Y). Sampel penelitian sebanyak 89 responden mahasiswa program studi pendidikan bahasa Arab tahun angkatan 2019 s/d 2022 IAIN Palangka Raya. Teknik pengumpulan data dengan Angket dan Dokumentasi. Teknik analisis data menggunakan analisis deskriptif dan analisis statistik. Hasil penelitian menunjukkan 1) Tingkat self confidence dengan nilai rata-rata 3,45 dominan pada kategori cukup. 2) Tingkat maharah al-kalam dengan rata-rata 83,02 dominan pada kategori baik. 3) Self confidence dan maharah al-kalam mahasiswa menunjukkan bahwa nilai p-value sebesar 0,143 > 0,05 yang berarti tidak memiliki korelasi.Kata Kunci: Self Confidence; Maharah Al-Kalam
Business Model to the LASSE performance at Microgrid environment
Authors: Polini W. ,   UNIOESTE- Paraná West State University Região Norte, Foz do Iguaçu, Paraná. Brazil, Lotero R.C. , Otto R.B. ,   LASSE - Automation and Electrical Systems Simulation Laboratory. Parque Tecnológico Itaipu - Foz do Iguaçu, Paraná. Brazil
Published: July 2024

The Microgrid (MG) scenario has a socioeconomic and technical character seeking to promote the sustainable, technological and economic advance. Through the MG, the consumer may set up its own business with a the sale of its own energy, thus, the Automation and Electrical Systems Simulation Laboratory (LASSE) is interested in participating of the MG market. Creating and/or innovating a business requires knowledge of the application environment. This reality has as consequence the determination of strategies for the company’s management in the vision of the market dynamics. This research aims to define the necessary requirements for the performance of LASSE in the MG environment and to develop the systemic LASSE diagram associating the structural elements of the business model with the characteristics of LASSE. The information was generated through the Business Model Generation (BMG) methodology, among which the Business Model Canvas tools stand out. The research interests LASSE for creating ideological guidelines for members of the LASSE Smart Energy Project. In this way, it is possible to clearly understand the process of introduction to the MG environment, as well as the necessary characteristics for the elaboration of Business Models (BM). Key words Smart Grid, Microgrid, Business Model, Systemic Vision
LED TV: Computational Modelling and Validation Under Ideal and Non-Ideal Supply
Authors: Rezende Paulo H. O. ,   FEELT - Universidade Federal de Uberlândia, Almeida Afonso B. , Gondim Isaque N. , de Oliveira José C. , Filho Carlos E. S. P. , Costanzi Jean E. , Cardoso Amilton F. ,   IFTM - Instituto Federal do Triângulo Mineiro,   FEELT - Universidade Federal de Uberlândia,   FEELT - Universidade Federal de Uberlândia,   Instituto de Pesquisa Eldorado,   Centrais Elétricas de Santa Catarina S.A. (CELESC),   Centrais Elétricas de Santa Catarina S.A. (CELESC)
Published: July 2024

This work proposes a computational modeling for LED TV’s in order to support reimbursement requests analysis. It is important to highlight the increasing number of requests concerning this device and the need of reliable models on simulation studies. These studies are performed to evaluate the relationship between causes and effects from dielectric and thermal nature, using an existing analysis software. This proposal is based on the equipment physical structure and, after the identification of its most common damage units, a computational modeling is implemented using ATPDraw software. In order to validate the strategy, experimental analysis are made and correlated with the computational results under ideal and non-ideal supply. Key words Power Quality, Reimbursement Requests, LED TV, Computational Modeling, Experimental Validation, ATPDraw.
PESTS INTENSITY IN POTATO (Solanum tuberosum) AND FABA BEAN (Vicia faba) INTERCROPPING IN SALARAN, GETASAN DISTRICT, SEMARANG REGENCY
Authors: Setiawan Andree Wijaya , Simanjuntak Bistok Hasiholan , Andhika Gideon Febby Prima
Published: July 2024

Tropical regions face threats from pests, leading to significant losses in the global potato supply. Intercropping potatoes with faba beans is being explored to control pest infestations in tropical areas. This study aims to provide insights into pest dynamics and improve pestmanagement strategies for sustainable potato cultivation. The research evaluates five cropping systems, each replicated across seven beds: potato monoculture, alternating growth of potatoes and faba beans at a 2:1 ratio, planting faba beans between the rows of potatoes at a 1:1 ratio, growing faba beans between two beds of potatoes, and cultivating solely faba beans. The study looked at various factors such as the type and intensity of pest attacks on potatoes. It found that planting faba beans alongside potatoes can help reduce aphid (Homoptera: Aphididae) and mirid bug (Hemipetra: Miridae) attacks, but may not affect grasshopper (Orthoptera: Acrididaeand Pyrgomorphidae) attacks. The distance between potato beds and the population of faba bean plants can also influence pest interactions. Understanding these dynamics offers important information for sustainable pest management practices in intercropping systems.
The clinical course of the novel coronavirus disease in children after allogeneic hematopoietic stem cell transplantation
Authors: Vereshchagina A. O. , Solopova G. G. , Bykova T. A. , Popova M. O. , Balashov D. N. , Suvorova N. V. , Rozanceva E. V. , Levin P. A. , Zubarovskaya L. S. , Novichkova G. A.
Published: July 2024

The clinical course of the novel coronavirus disease (COVID-19) in patients with oncological and hematological diseases after hematopoietic stem cell transplantation (HSCT), are of special interest. To further investigate the problem, a two-center study was undertaken at the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology and the R.M. Gorbacheva National Research Institute for Pediatric Oncology, Hematology and Transplantation between January 2020 and January 2023. This was a retrospective-prospective, non-randomized, non-interventional study that included children aged 0–19 years with oncological and hematological diseases and primary immunodeficiencies who had undergone allogeneic HSCT and subsequently contracted COVID-19. The study was approved by the Independent Ethics Committee and the Scientific Council of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. COVID-19 cases were confirmed by polymerase chain reaction testing and classified as asymptomatic, mild, moderate, severe, and critical. The study included 105 patients with a median age of 9 years; male patients were predominant (the male-to-female ratio was 1.8:1). The primary diseases were hematological malignancies (73%), benign hematological diseases (14%) and primary immunodeficiencies (13%). The most common clinical symptoms of COVID-19 were fever, gastrointestinal symptoms, and respiratory symptoms; 40% of COVID-19 cases were asymptomatic. Lymphopenia was found to be a risk factor for severe COVID-19. The patients without immune reconstitution had a longer persistence of the COVID-19 virus than those with immune reconstitution (17 days versus 13 days), however, no significant differences were obtained (p = 0.7). There were also no significant differences in the severity and outcomes of COVID-19 between the patients with immune reconstitution and those without reconstitution. There was no effect of therapy on the duration of COVID-19, and there was no association between the type of treatment and the duration of the disease. The overall survival rate in the allo-HSCT recipients who had been diagnosed with COVID-19 was 88%, which was lower than in the non-recipients (88% vs 94%; p = 0,077).
Chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Authors: Skvortsova Yu. V.
Published: July 2024

Chronic graft-versus-host disease (GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation (HSCT) caused by immune dysregulation leading to multisystem involvement resulting in tissue sclerosis. This is a long-term complication that can significantly affect the quality of life of HSCT recipients due to secondary immunodeficiency associated with combined immunosuppressive therapy, impaired organ function and even disability. In addition to active prophylaxis for chronic GVHD, regular follow-up of patients is necessary for early detection of signs and symptoms of GVHD to enable timely and effective treatment. Here, we present a brief overview of novel approaches to diagnosis, classification, and staging of chronic GVHD, as well as current prophylaxis and treatment options.
A case of allogeneic hematopoietic stem cell transplantation in a patient with hyper-IgE syndrome
Authors: Bazaev A. A. , Kozlovskaya S. N. , Vasilyeva A. P. , Skvortsova Yu. V. , Balashov D. N.
Published: July 2024

Classic hyper-IgE syndrome (due to a mutation in the STAT3 gene) is a primary immunodeficiency associated with multisystem disorder affecting organs and tissues. To date, there are only few published cases of hematopoietic stem cell transplantation for this disease, which does not allow us to fully assess the main effects of transplantation in this group of patients. This article presents a clinical case of hematopoietic stem cell transplantation from an unrelated donor with TCRab/CD19 depletion in a patient with hyper-IgE syndrome, which was carried out at the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. The patient's parents gave consent to the use of their child's data, including photographs, for research purposes and in publications. At 5 years after treatment, the patient has a good graft function and no signs of immunodeficiency, and infectious complications remain controlled. However, despite accompanying bisphosphonate therapy and the absence of osteopenia signs according to densitometry, the patient still has musculoskeletal disorders, associated with spontaneous long bone fractures and severe joint deformities.
The structure of hemostatic aggregate and the assessment of platelet functional activity using flow cytometry
Authors: Balandina A. N. , Kuprash A. D. , Nikitin N. S. , Kovalenko T. A. , Ignatova A. A. , Ataullakhanov F. I. , Panteleev M. A.
Published: July 2024

A thrombus is a heterogeneous structure consisting of platelets in different functional states. Flow cytometry is one of the most promising tools for the diagnosis of platelet state. However, its optimization and standardization are the subjects of heated debate. How to properly activate and label platelets in order to assess their functional status? In this work, we would like to briefly highlight this issue and propose the hypothesis that several levels/types of platelet activation correspond to various positions in the thrombus and various physiological meanings. One should use this entire necessary and sufficient set of activation levels in order to draw a conclusion about how the patient’s platelets “feel”.