bluuebunny/crossref_metadata_2025 huggingface dataset:
Emotional Exhaustion and Professional Satisfaction during Covid-19 Pandemic at the Level of Emergency Department Staff
Authors: Moscu Cosmina-Alina , Anghele Mihaela , Dragomir Liliana , Munteanu Sorina , Anghele Aurelian , Nechita Aurel , Ciubară Anamaria
Published: July 2021

Introduction: Burnout is a syndrome conceptualized as result of the chronic stress at the work place which was not successfully managed. The possible negative effects on the medical staff, the patients and the health institutions have generated interest and motivated the research to understand the possible causes, these effects also influence the burnout predictors. The medical services suppliers within the emergency department have had one of the greatest exhaution occurences even before the pandemic. Being in the first line in contact with the suspected patients or confirmed with COVID-19 infection intensifies this fact. Both the working factors (working hours, years of practice, number of treated patients, professional development activities) and the socio- demographic factors (age, sex, civil status, income, education) are associated with the exhaustion at the work place. Material and methods: I have studied a total of 120 participants, receiving 115 valid questionnaires, the answering ratio being 95,83%. This was a descriptive, multicentre, transversal study of the medical and the auxiliary staff within the department UPU-SMURD of the County Clinic Emergency Hospital “Sf. Ap. Andrei” Galați. The staff gave their consent and attended a combined interview which consisted of a pilot questionnaire and a demographic questionnaire. Results and discussions: The average score of exhaustion at the staff level was 3.25, a great percentage of the doctors within the ED (45.8%), (n=24) indicates an increased level of exhaustion, only 26.8% (n=80) of nurses show an increased level of exhaustion. The average score of the stress level shown by the staff is 3.1, 66.6% (n=24) among which the doctors with an increased stress level 9.1% (n=9) auxiliary staff, 23.8% (n=80) of nurses. Conclusions: The results show us a high exhaustion, stress and depression ratio at the emergency doctors in comparison with the other professional categories within the ED. A high level of professional satisfaction is accompanied by an increased level of stress and of self-esteem.
Porównanie modeli prędkości obliczonych z wykorzystaniem różnych wariantów prędkości i algorytmów na profilu sejsmicznym 2D na potrzeby migracji czasowej po składaniu
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Bajewski Łukasz , Wilk Aleksander ,   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Urbaniec Andrzej ,   Instytut Nafty i Gazu – Państwowy Instytut Badawczy
Published: July 2021

This article presents a construction method of the velocity field for poststack time migration for 2D seismic calculated on the basis of interval velocities in boreholes and structural interpretation, as well as the results of poststack time migration based on this solution. Three velocity field models have been developed. The models used differ in the way of spatial interpolation and extrapolation in the adopted calculation grid in the depth domain, which was created on the basis of a structural interpretation of 2D seismic profiles. Three methods of interpolation and extrapolation were used: Gaussian distribution, kriging and moving average. The spatial distribution of the interval velocities in the boreholes was made using the Petrel software by Schlumberger. The interval velocities along the analyzed seismic profile were extracted from the computed spatial interval velocity models, and after conversion from the depth to the time domain, they were used for the poststack time migration. For comparison, poststack time migration was calculated for the same seismic profile based on the stacking velocities obtained in the seismic processing data as a result of velocity analyzes. The velocity field calculated on the basis of interval velocities and structural interpretation was used for the poststack time migration procedure performed with the Implicit FD Time Migration algorithm (finite difference), while the stacking velocities were used for the poststack time migration procedure performed with the Stolt and Kirchhoff algorithms in accordance with the technical conditions of correct operation of these algorithms. The selected percentage ranges of 60%, 100%, and 140% have been used for all velocity fields. Application of the element of directional velocity variation resulting from the spatial distribution of interval velocities in the boreholes to the velocity field for the poststack time migration allowed to obtain a better seismic image in relation to the one obtained as a result of applying the stacking velocities. The most reliable seismic image after poststack time migration was obtained for the velocity field calculated on the basis of the interval velocities with Gaussian distribution, using the finite difference algorithm with 60 percent value of the velocity field.
Stabilność termooksydacyjna smarów plastycznych
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Skibińska Agnieszka
Published: July 2021

This review article deals with a particular property of lubricating greases – resistance to oxidation. This property, also referred to as oxidative or thermal oxidation stability, has a decisive influence on the quality and duration of lubricating greases service life in friction nodes, bearings and lubrication systems. Lubricating greases are colloidal systems in which the thickener creates an elastic three-dimensional network, maintaining the liquid phase. The structure of lubricating greases, division of greases into types, depending on the thickener used, is presented. The basic additives in lubricating greases are described, and the group of used antioxidant additives is discussed in detail. Under operating conditions, the grease is subject to factors that cause its destruction – shear stress, pressure, loads, changing operating conditions, especially temperature changes. The types of lubricating greases degradation are presented, as well as methods and techniques of aging processes evaluation. During operation, the grease fulfilling its basic functions in the lubrication system is primarily exposed to high temperatures. The predominant aging process which directly affects the service life of the grease is oxidation. The oxidation process is discussed, with the specification of its four stages: initiation, propagation, chain branching and termination. One of the methods of preventing the oxidation process is the selection of appropriate improvers. Thermal oxidation stability of greases can be modified by introducing appropriate antioxidants, the selection of which depends on the type of grease thickener and the operating temperature of the grease. The published literature review from over the last ten years shows how diverse are the ways of modifying thermal oxidation stability of greases and the methods of assessing this property.
Effect of Probiotic Enterococcus gallinarum N3 Supplemented Feed on Growth Performance of Freshwater Fish Cyprinus carpio
Authors: Totewad N.D. , Gyananath G.
Published: July 2021

Background: Probiotic is the best solution (Produce antimicrobial compounds, inhibit colonization of pathogenic microorganism, increase digestive ability and confer better health to the host) as an alternative to antibiotics against various microbial infection in freshwater and marine water. The freshwater fish Cyprinus carpio was selected for this research work (due to high growth rate, high protein content, ability to survive under different climatic conditions and its availability throughout the year) to observe the effect of probiotic Enterococcus gallinarum N3 supplemented feed on its growth. Methods: In this present research work Prepared three different concentration of probiotic Enterococcus gallinarum N3 (0.1%. 0.5% and 1.0%) along with basal diet containing other ingredients (fish meal, groundnut oil cake, wheat bran, starch and Vitamin mineral premix). Initially 14 days acclimatized freshwater fish Cyprinus carpio to laboratory condition selected randomly for four treatment groups as Control (C) and probiotic feed treated T1, T2 and T3 group. The experiment was carried out for 42 days with continuous aeration, natural photoperiod of 16 hrs light and 8 hrs dark, maintain temperature constant and fishes fed diet twice daily. The feed ingredients and experimental diets analysed for proximate composition and measured Weight gain, Specific growth rate (SGR), and Feed conversion efficiency (FCE). Result: The proximate composition of the feed was determined as percentage dry matter in which 36.21% protein, 6.8% moisture and 7.8% of lipid. The probiotic feed experiment was conducted for 42 days and entire group of fishes was survived. The effect of probiotic feed on growth performance of Cyprinus carpio was measured as initial weight, final weight, weight gain, specific growth rate and feed conversion efficiency. The growth changes were observed before and after treatment with 0.1%, 0.5% and 1.0% of probiotic E. gallinarum N3 fed to Cyprinus carpio. The final weight (g) and final length (cm) was measured in treatment T1 (3.107 g; 3.32 cm), T2 (3.258 g; 3.40 cm) and T3 (3.413 g; 3.52 cm) respectively as compared with Control group C (2.255 g; 2.98 cm). The percentage weight gain obtained in group T1 (37.78%), T2 (44.45%) and (51.55%) respectively as compared with Control group C (29.54%). Maximum specific growth rate was observed in treatments T1 (0.94 % day-1), T2 (0.99% day-1) and T3 (1.02% day-1) as compared with control group C (0.56% day-1). The results showed better growth performance and feed utilization in all the three treated groups T1, T2 and T3. The best growth performance (final weight, final length, weight gain, specific growth rate and feed conversion efficiency) and feed utilization (moisture, protein and lipid) was observed best in T3 (1 g kg-1) group of fishes as compared to control C group. There was significant difference (P greater than 0.05) in final weight, final length, weight gain, specific growth rate and feed conversion efficiency.
​Insect Plant Interaction with Reference to Secondary Metabolites: A Review
Authors: Afroz Mansura , Rahman Md. Mamunur , Amin Md. Ruhul
Published: July 2021

Plant and herbivorous insect share a contradictory but everlasting relationship. To cope with the herbivores, plant invested its energy in the production of various defensive chemicals which are known as plant secondary metabolites (PSMs). During coevolution with plants, insects also adapted themselves to counter plant defensive mechanisms. The secreted saliva and ovipositional fluids of insects induce the production of secondary metabolites in plants. Plants also produce compounds constitutively in the tissues that are susceptible to insect attack. These compounds reduce insect growth and development of insects through interfering with the developmental phases, acting as feeding deterrent, reducing nutritive value, affecting protein digestion and the production of substances toxic to them. On the contrary, insect’s adaptations to PSMs include the detoxification of plant toxins, conversion of the toxic compounds into conducible form for its growth and development, development of feeding choice based on the concentration of PSMs, quicker absorption and elimination as feces and obtaining the help of symbiotic intestinal microorganism to inactivate toxic materials. Furthermore, insects also utilize PSMs as chemical cues mediated through their chemoreceptive systems. The selection of host plants by monophagous insect is sometimes concentrated on the production of particular PSMs. Secondary metabolites also act as attractant to insect pollinators by exhibiting distinctive odors. Insects also store toxic PSMs which are used by them against their predators and in giving protection to eggs. However, this intrinsic capability of plants to produce defensive chemicals in response to insect attack should be explored to a wide extent to optimize the performance of PSMs.
​Sex Ratio of Calves Resulted from Artificial Insemination Implementation using Sexed Semen with Percoll Gradient Density Centrifugation Method in Ongole Crossbred Cows
Authors: Susilawati T. , Bustari W.O. , Crisara I.P.B. , . Kuswati , Huda A.N. , Satria A.T. , Yekti A.P.A.
Published: July 2021

Background: Productivity of existing cattles in Indonesia is necessarily to be increase to balance meat consumption in this country. Determination of offspring of certain sex can be obtained from Percoll gradient density centrifugation.The purpose of this research was to elucidate the proportion of male calves that can result from artificial insemination using single and double doses of sexed semen in Ongole crossbred cows. Methods: The sexed semen samples were obtained through Percoll gradient density centrifugation performed by the Artificial Insemination Center. The artificial insemination method adopted here was deep insemination. As much as 10 ml of BIO ATP® (Rheinvet) was injected in each cow before immediately insemination. Further, as much as 3 kg/day of additional feed was given over three days after insemination, with a protein level of about 12%. Result: Our results showed the proportion of Y-bearing sperm among non-sexed semen was 52.77% and among sexed semen, was 80.79%. Further, 54.17% of the non-sexed semen, 42.11% of the single-dose sexed semen and 78.95% of the double-dose sexed semen treatments yielded male calves.
​Evaluation of Terminalia arjuna in Comparison to Taurine against Experimental Nephrotoxicity due to Cisplatin in Rats
Authors: Sneha K. , Reddy A. Gopala , Rani M. Usha , Ramya B. , Kumar P. Shiva , Kumar B. Anil
Published: July 2021

Background: Cisplatin is one of the most remarkable solutions in ‘the war on cancer’. Although cisplatin has been a mainstay for cancer therapy, its use is mainly limited by nephrotoxicity. The current study was aimed to evaluate the ameliorative potential of Terminalia arjuna (TA) in comparison to taurine against cisplatin toxicity. Methods: A total of 36 male Wistar rats were divided into 6 groups of 6 rats in each. Group 1 was normal control. Cisplatin @ 5 mg/kg b.wt was injected on day 1 to groups 2, 5 and 6. Aqueous leaf extract of Terminalia arjuna was administered orally @ 400 mg/kg b. wt to groups 3, 5 and Groups 4, 6 recieved taurine orally @ 1000 mg/kg b.wt for 14 days. Blood samples were collected from animals to assess Kidney function tests, oxidative stress and cytokines and renal tissues were examined for histological changes, if any. Result: Antioxidant profile, serobiochemical and cytokine parameters were significantly (P less than 0.05) increased and histopathological studies revealed degenerative changes and marked infiltration in the kidney of group 2 when compared to groups 1, 3 and 4. However, These changes were reversed in groups 5 and 6 that were administered with Terminalia arjuna and taurine, respectively. In conclusion, the results of the present investigation elucidated that both Terminalia arjuna and taurine have potent nephroprotective activity in cisplatin injected Wistar rats.
Mempertahankan Motilitas dan Viabilitas Spermatozoa Babi dalam Pengencer Air Kelapa Kuning Telur Bebek dengan Pengimbuhan Sari Wortel
Authors: Apriliana Kadek Soma , Bebas Wayan , Trilaksana I Gusti Ngurah Bagus
Published: July 2021

Penelitian ini dilakukan untuk mendapatkan pengencer semen babi yang murah, berkualitas, dan mudah dibuat dengan menggunakan air kelapa dan kuning telur yang ditambahkan sari wortel. Penelitian ini menggunakan satu ekor babi Landrace jantan dan penampungan semen dilakukan dengan metode massage. Penelitian ini menggunakan Rancangan Acak Lengkap, terdiri dari dua perlakuan, yaitu perlakuan satu: semen babi diencerkan dengan pengencer air kelapa kuning telur bebek; dan perlakuan dua: semen babi diencerkan dengan air kelapa kuning telur bebek dengan penambahan sari wortel 1%. Semen yang telah diencerkan disimpan pada suhu 18-20ºC dengan lama penyimpanan masing-masing: 0 jam, 4 jam, 8 jam, 12 jam, 16 jam, 20 jam, 24 jam, 28 jam dan 32 jam. Masing-masing perlakuan diulang sebanyak tiga kali, sehingga jumlah sampel yang digunakan adalah 27 sampel untuk setiap perlakuan. Selama penyimpanan dilakukan pengamatan terhadap motilitas dan viabilitas spermatozoa. Data yang diperoleh dianalisis dengan uji sidik ragam, dan bila terdapat perbedaan yang bermakna maka dilanjutkan menggunakan uji Duncan. Hasil penelitian menunjukkan lama simpan semen dalam pengencer air kelapa kuning telur bebek dengan penambahan sari wortel berpengaruh nyata terhadap motilitas dan viabilitas spermatozoa babi Landrace. Penambahan sari wortel mampu mempertahankan motilitas progresif selama 20 jam dengan persentase 41,39%, sedangkan viabilitas dipertahankan selama 28 jam dengan persentase 45,45%.
Identifikasi dan Prevalensi Jamur Curvularia pada Anjing dan Kucing di Kabupaten Badung, Bali Tahun 2020
Authors: Sudipa Putu Henrywaesa , Gelgel Ketut Tono Pasek , Jayanti Putu Devi
Published: July 2021

Curvularia adalah genus Pleosporalean monophyletic dengan banyak jenis spesies, termasuk jenis fitopatogenik, jamur patogen pada hewan dan manusia. Curvularia juga menyebabkan phaeohyphomycosis yang mana ditemukan pada invertebrata, vertebrata berdarah dingin, burung dan spesies mamalia termasuk ruminansia, kuda, anjing, kucing dan manusia. Penelitian ini bertujuan untuk mengidentifikasi dan mengetahui prevalensi Curvularia pada anjing dan kucing. Sampel diambil dengan cara menggunakan teknik sitologi kulit dengan menggunakan plester selotip (tape) yang ditempelkan pada bagian tubuh yang mengalami infeksi jamur kemudian ditempelkan pada gelas objek yang sudah diberikan beberapa tetes pewarna methylene blue. Sampel menggunakan 34 sampel (26 ekor anjing dan 8 ekor kucing) dan sampel diperiksa dibawah mikroskop cahaya dengan pembesaran 100 kali. Pemeriksaan mikroskopis sampel melihat karakteristik jamur, terutama pigmentasi, septasi, morfologi, ukuran hifa, konidiofor dan konidia. Dari data jenis jamur yang teridentifikasi kemudian data ditabulasi dan dijelaskan secara deskriptif. Hasil yang didapatkan adalah prevalensi Curvularia pada anjing adalah 19%, pada kucing 50% dan total infeksi Curvularia dari seluruh sampel berjumlah 26%. Culvularia yang teridentifikasi adalah tipe konidia tipikal yang bentuk konidiumnya obovoid, melengkung, agak membengkak pada satu sel, gelap, dan dindingnya tebal dan tipe konidia atipikal yang bentuknya lurus dan menyempit ke arah ujung, konidiofor tidak bercabang, dan berbentuk zigzag serta jumlah septa berjumlah 3-4 atau eusepta.
Laporan Kasus: Penanganan Katarak pada Anjing Pomeranian dengan Pemberian Antioksidan Berkualitas Tinggi
Authors: Areningrat Putu Ayutia , Widyastuti Sri Kayati , Anthara Made Suma
Published: July 2021

Katarak merupakan penyebab umum kebutaan pada anjing ras Pomeranian. Katarak adalah suatu kondisi pada mata yaitu cahaya tidak dapat menembus lensa mata atau hilangnya transparansi lensa mata (opacity). Hewan kasus adalah seekor anjing ras Pomeranian dengan jenis kelamin jantan, umur delapan tahun, berat badan 5,6 kg, warna rambut coklat kehitaman. Bola mata bagian kiri terutama bagian lensa anjing kasus berwarna putih terang. Adanya abnormalitas pada mata sebelah kiri pada anjing Pomeranian ini mulai terlihat pada empat bulan lalu. Hewan kasus belum pernah diberikan pengobatan apapun. Pengujian refleks palpaebrae di kedua mata anjing terlihat mata kiri masih menunjukkan refleks palpaebrae. Pada pengujian refleks pupil di kedua mata anjing, mata sebelah kiri tidak menunjukkan adanya refleks pupil terhadap cahaya. Pada pemeriksaan fluorescein terlihat tidak adanya warna yang terserap dikedua mata anjing yang menunjukkan bahwa tidak terdapat ulcer di kedua mata anjing kasus. Berdasarkan tanda klinis, hasil pemeriksaan menggunakan ophtalmoskop serta hasil pemeriksaan menggunakan tes fluorescein, anjing kasus didiagnosa katarak. Prognosa hewan kasus adalah dubius. Anjing kasus diberikan suplemen herbal yaitu eyevit® sebanyak dua tablet sehari yang setara dengan 160 mg ekstrak bilberry kering, ?-carotene 10 mg, Vitamin E 80 mg, lutein 500 mg, zeaxanthin 120 mcg, selenium 30 mcg dan zinc 10 mg. Suplemen dengan kandungan antioksidan tersebut dapat memperlambat perkembangan katarak.
Laporan Kasus: Menangani Penyakit Ginjal Kronis pada Anjing Peranakan Pomeranian
Authors: Pradnyani Gusti Ayu Putu Indira , Widiastuti Sri Kayati , Erawan I Gusti Made Krisna
Published: July 2021

Penyakit ginjal kronis atau Chronic Kidney Disease (CKD) adalah gangguan fungsi ginjal yang bersifat progresif dan irreversible. Seekor anjing peranakan pPomeranian Mix bernama Kitty, berumur 10 tahun, jenis kelamin betina diperiksa di Klinik Hewan Sunset Vet Bali. Anjing kasus memiliki riwayat gangguan jantung dan hati. Anjing kasus kembali datang ke klinik diduga mengalami gangguan ginjal. Anjing kasus mengalami poliuria, muntah, anoreksia, diare dan lethargy. Anjing kasus juga mengalami penurunan berat badan setiap bulannya. Pada pemeriksaan fisik ditemukan Body Condition Score (BCS) yaitu 5/9, frekuensi napas 60 kalix/menit, frekuensi detak nyut jantung 150 kalix/menit (takikardia), auskultasi jantung terdengar suara bising-bising/murmur jantung. Pemeriksaan hematologi rutin menunjukkan anjing kasus mengalami polisitemia dan mengalami kelainan morfologi eritrosit yaitu mikrositik. Pada pemeriksaan biokimia serum terjadi peningkatan kadar Blood Urea Nitrogen, kreatinin, fosfat, globulin dan penurunan kadar kalsium dan natrium. Pada pemeriksaan berat jenis urin diperoleh hasil 1,015 dan pemeriksaan Symmetric Dimethylarginine (SDMA) diperoleh hasil 15 μg/dL. Terapi dilakukan dengan diet, terapi cairan, maropitant, furosemide, ipakitine powder, enalapril dan kalsium glukonat. Setelah dirawat selama lima hari anjing kasus menunjukkan kondisi yang lebih baik, yaitu tidak adanya muntah, anjing kasus mulai responsif dan tidak ada diare. Pada hari ke-10 dilakukan beberapa parameter pengujian serum biokimia darah meliputi pemeriksaan kadar BUN mengalami penurunan dari pemeriksaan awal walau pun masih di atas normal, sedangkan kadar kreatinin, fosfat dan kalsium berada pada rentangan nilai normal.
STILOVI LJUBAVI I PARTNERSKA AFEKTIVNA VEZANOST
Authors: Шакотић-Курбалија Јелена М.
Published: July 2021

U cilju utvrđivanja značajnosti razlika u stavovima prema ljubavi među individuama različitih obrazaca partnerske afektivne vezanosti, prikupljeni su podaci na uzorku od 451 ispitanika (51.9% ženskog pola) u vezi ili neformalnom braku-kohabitaciji, starosti od 19 do 45 godina. Za identifikovanje obrazaca partnerske afektivne vezanosti primenjena je skraćena verzija Inventara iskustava u partnerskim odnosima, dok je Skalom ljubavnih stavova procenjeno šest stilova ljubavi: Eros, Ludus, Storge, Pragma, Manija, i Agape. Sigurno vezani ispitanici ostvaruju više skorove na Eros i Agape ljubavnom stilu, a niže na ljubavnom stilu Ludus, u odnosu na ispitanike sa izbegavajućim obrascem; niže skorove na ljubavnim stilovima Pragma i Manija u odnosu na ispitanike sa preokupiranim obrascem; i niže skorove na ljubavnim stilovima Ludus, Storge, Pragmi i Maniji, u odnosu na ispitanike sa bojažljivim obrascem partnerske afektivne vezanosti. Ispitanici sa preokupiranim obrascem ostvaruju više skorove na ljubavnim stilovima Eros, Manija i Agape, a na ljubavnom stilu Ludus niže skorove u odnosu na ispitanike sa izbegavajućim obrascem, kao i niže skorove na Ludus stilu ljubavi u odnosu na ispitanike sa bojažljivim obrascem partnerske afektivne vezanosti. Individue sa bojažljivim obrascem ostvaruju više skorove na ljubavnom stilu Manija u odnosu na ispitanike sa izbegavajućim obrascem partnerske afektivne vezanosti.
LEPOTA, MAČ I MOLITVA: LIK STAROZAVETNE UDOVICE IZ VETULIJE U STVARALAŠTVU MARKA MARULIĆA I GAVRILA KOVAČEVIĆA
Authors: Eraković Radoslav , Varnica Nevena
Published: July 2021

U ovom radu predstavljeni su rezultati uporedne analize poetsko-epskih ostvarenja Marka Marulića (1450–1524) i Gavrila Kovačevića (1765–1832), inspirisanih podvigom starozavetne junakinje Judite (Marulić 1521; Kovačević 1808). Posmatrano iz savremene književnoistorijske i kulturološke perspektive, način na koji je preoblikovana tematska struktura starozavetnog predloška u delima dvojice južnoslovenskih pesnika, potvrđuje ispravnost teorijske pretpostavke o uticaju drevnih mitova na stvaranje i oblikovanje nacionalno-imagotipskih sistema (Fischer, 2009). Naime, pseudofaktografsko stapanje prelomnih događaja iz istorija različitih carstava (vavilonskog, asirskog, pa čak i turskog) opravdalo je postupak hiperbolizacije vojne moći demonizovanih nevernika, koje je trijumfalno porazio malobrojni ali pobožni narod. U inicijalnoj fazi ovog istraživačkog poduhvata posebna pažnja bila je posvećena tumačenju intertekstualnih veza između popularne deuterokanonske pripovesti i spevova dvojice autora, čija dela nikada do sada nisu bila predmet komparativnog iščitavanja. Ovakav pristup književnoistorijskoj građi, omogućio je preciznije identifikovanje nedovoljno proučenih žanrovskih, poetičkih i tematskih linija dodira između reprezentativnih segmenata stvaralačkog opusa renesansnog i predromantičarskog pesnika.
Precariedade, precarização e precariado no sistema capital do século XXI – “Você não estava aqui”
Authors: Souza Iael
Published: July 2021

Este artigo discute a precariedade e precarização das condições existenciais e de trabalho da classe trabalhadora, o surgimento do precariado como “nova camada” dessa classe e a intensificação da precariedade e precarização da classe trabalhadora com a reestruturação produtiva do capital e sua atual fase de acumulação. O filme “Você não estava aqui” é utilizado para enfatizar alguns dos aspectos da precarização e precariedade da condição existencial e de trabalho dos trabalhadores assalariados de todo o mundo. Também são tecidas algumas breves considerações sobre como a SARS-COV-2 escancara a situação de precariedade e precarização da classe trabalhadora, intensificada com a política-econômica de austeridade na área social e a flexibilização trabalhista do capital neoliberal.
Molecular Diagnosis of SARS-CoV-2: Assessing and Interpreting Nucleic Acid and Antigen Tests
Authors: Zimmerman Peter , King Christopher , Ghannoum Mahmoud , Bonomo Robert , Procop Gary
Published: July 2021

In this review, we summarize the current status of nucleic acid and antigen testing required for diagnosing SARS-CoV-2 infection and COVID-19 disease. Nucleic acid amplification (NAAT) and antigen-detection (Ag) tests occupy a critically important frontline of defense against SARS-CoV-2 in clinical and public health settings. In early stages of this outbreak, we observed that identifying the causative agent of a new illness of unknown origin was greatly accelerated by characterizing the nucleic acid signature of the novel coronavirus. Results from nucleic acid sequencing led to the development of highly sensitive RT-PCR testing for use in clinical settings and to informing best practices for patient care, and in public health settings to the development of strategies for protecting populations. As the current COVID-19 pandemic has evolved, we have seen how NAAT performance has been used to guide and optimize specimen collection, inform patient triage decisions, reveal unexpected clinical symptoms, clarify risks of transmission within patient care facilities, and guide appropriate treatment strategies. For public health settings during the earliest stages of the pandemic, NAATs served as the only tool available for studying the epidemiology of this new disease by identifying infected individuals, studying transmission patterns, modeling population impacts, and enabling disease control organizations and governments to make challenging disease mitigation recommendations to protect the expanding breadth of populations at risk. With time, the nucleic acid signature has provided the information necessary to understand SARS-CoV-2 protein expression for further development of antigen-based point-of-care (POC) diagnostic tests. The advent of massive parallel sequencing (ie, next generation sequencing) has afforded the characterization of this novel pathogen, informed the sequences best adapted for RT-PCR assays, guided vaccine production, and is currently used for tracking and monitoring SARS-CoV-2 variants.
Vasculitis ANCA positiva inducida por Propiltiouracilo. Reporte de caso
Authors: Soto Fonseca Marco Antonio , Medina Ramírez Katherine Fernanda , Sánchez Barjún Karen
Published: July 2021

La vasculitis asociada a propiltiouracilo (PTU) y ANCA es una enfermedad rara con una incidencia de 0,47-0,71 casos por cada 10 000 pacientes. Afecta principalmente a los vasos de menor calibre. Piel, riñones y pulmones son los más afectados. El diagnóstico requiere alta sospecha clínica y se apoya en estudios histopatológicos de las lesiones en piel y serología positiva para ANCA. La suspensión del medicamento suele bastar como manejo de la enfermedad. Mujer de 45 años de edad, con historia de consumo de PTU durante 2 años, desde su diagnóstico de hipertiroidismo; presentando placas purpúricas dolorosas en ambos miembros inferiores.
Participaron como revisores de los artículos presentados a la Revista Médica Herediana en el año 2020
Authors: Editorial Revista Médica Herediana Comité
Published: July 2021

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Assessment of New Protected Mechanism of Liraglutide on CKD Progression
Authors: Hayder Hussein Luaibi  , Mustafa Ghazi Al-Abbassi  , Israa Burhan Raoof  , Zakariya AL-Mashhadani
Published: July 2021

Podocyte injury represents the main reason for proteinuria and renal disease in diabetic and non-diabetic patients. Recently Liraglutide as a GLP-1 analog is hypothesized to play a vital role in preventing kidney damage by anti-inflammatory and anti-apoptotic effect mechanisms. This study was established to evaluate the effect of Liraglutide on deterioration that happens with time in chronic kidney disease. 36 male Wister rats with a weight of 250-300 g were used in this study. All selected animals were examined and determined to be normal on general examination. Rats were divided into three groups (12rats/group): control group: negative control group injected normal saline I.P, induction group: single I.P dose (7.5 mg/kg) of doxorubicin for 14 days then administered 0.5ml/kg normal saline intraperitoneal for 28 days, and treatment group: single I.P dose (7.5 mg/kg) of doxorubicin for 14 days then administered I.P Liraglutide 200μg/kg/day freshly dissolve in 0.5ml /kg normal saline 28 days. The treatment group appeared significantly decreased (P< 0.05) in the pro-inflammatory expression of TNF-α as compared with the induction group, while the treatment group revealed a significant increased (P< 0.05) in the expression of anti-apoptotic BCL-2 in the proximal tubule of the kidney. Besides the effect of Liraglutide on renal deterioration by lowering blood glucose, the main causes of oxidative stress, Liraglutide as GLP-1 analog can reduce the consequence of proteinuria in the cases of glomerulosclerosis and tubulointerstitial damage by decreased pro-inflammatory TNF-α expression and increase expression of BCL-2 in that cell.
Hematological Implications of Schistosomiasis: Experimental and Clinical Review
Authors: Mohammad Aziz Al-Kazzaz  , Marwa Elhamy
Published: July 2021

This review aimed to explore the deleterious effects of Schistosoma infection on the blood picture of infected hosts. International and local scientific search engines were navigated from till April 2021 for systematic reviews, clinical trials and experimental studies that address the hematological profile of the schistosomiasis-infected patients.  Anemia and eosinophilia are the characteristic hematological findings of schistosomiasis but controversy was found regards the effects of schistosomal infection on other blood cells which may be due to discrepancy in infected hosts, Schistosomes strains, various laboratory methodologies or phase of the disease.
Computer-aided Validation of Fluorobenzimidazole as Soluble Epoxide Hydrolase Inhibitor: An In-Silico Study
Authors: Bedanta Bhattacharjee  , Ritu Bharti  , Karabi Kalita  , Nirupam Das  , Abu Md Ashif Ikbal
Published: July 2021

Soluble epoxide hydrolase (sEH) is an enzyme and is encoded by the gene EPHX2 in human beings. Indeed, by inhibiting the biotransformation of these epoxide(s) via arresting the action of the mammalian sEH one can develop a promising antihypertensive drug(s). The present work was emphasized the possible binding mode of fifteen fluorobenzimidazole (4a-4o) derivatives as soluble epoxide hydrolase (sEH) inhibitors. The X-ray crystal structure of human sEH in complex with the inhibitor 6NJ [(3-(2-phenylethyl)-1H-indazole] has been utilized to select the specific active site of protein data bank (PDB) ID: 5AKY with resolution: 2.18 Å for the docking study.The energy conformer of trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid (tAUCB) was docked using the prepared grid towards validation of the generated grid and docking protocol. The best results obtained by the ligands 4f, 4g and 4m with a dock score -9.94, -9.75, and -11.56, respectively. Among all the ligands, 4m exhibited considerable “drug-like” characteristics with the highest G score and possess acceptable in-silico pharmacokinetic by obeying Lipinski rule of five. In conclusion, compound 4m might be used as a lead molecule in the antihypertensive drug discovery.
Prevalence and Epidemiological Study of hepatitis B and C patients admitted to BEN AMOR DJILANI hospital in El Oued, Algeria
Authors: Derouiche Samir
Published: July 2021

The Goal of the present study is to evaluate the epidemiological variations of hepatitis B and C in El Oued population. Our epidemiological study was carried out on 1798 hepatitis patients admitted to hospital BEN AMOR DJILANI the period (January 2013 to December 2020) in El Oued region. In Results, 5.45% of patients were aged less than 20 years 72.14% of the patients are aged between 20-40 years, 15.85% patients are ages between 40-60 years and 6.56 % patient are aged more than 60 years. In the other hand, 57.29% of hepatitis patients are men versus 42.71% are women. In this study, 95% of the patients had a hepatitis B whereas 5% of the people were affected by hepatitis C. Concerning regions of hepatitis patients, the eastern region include the highest number with 37%, followed by - with a small difference - the central region with 33%, then come the southern region with 18%, the northern region contain 11% and at least the western region which include the lowest number of hepatitis patients with 1%, of total cases of hepatitis patients in the state of El Oued. Hence epidemiological studies are needed to understand and improve facilities and implement effective treatment measures to control the disease and thus help to reduce mortality in the society associated with this disease.
Antioxidant Activity, Total Phenolic and Flavonoid Contents of Sesbania pachycarpa (Fabaceae) Leaves’ Extract
Authors: Jeweldai Vedekoi  , Sokeng D. Selestin
Published: July 2021

The aim of this present work was to screen the phytochemicals compounds and, to determine the total ﬂavonoid and total phenolic contents as well as an antioxidant potential of an aqueous extract of Sesbania pachycarpa leaves. During this process, the quantities of total phenolic content of the extract were measured using the Folin-Ciocalteu reagent, whereas aluminum chloride colorimetric method was analyzed for total flavonoid determination. The antioxidant activity of leaf extract was determined by the 1,1-Diphenyl-2-Picrylhydrazyl radical scavenging (DPPH) activity test, whereas the Ferric Reducing Antioxidant Power (FRAP) activity was determined through spectrophotometrically analysis. The results showed that the aqueous extract exhibited the altered DPPH free radical scavenging activity (IC50 = 0.921 mg/mL) and FRAP activity tests (IC50 = 0.173 mg/mL) compared to that of the positive controls ascorbic acid (IC50 = 1.099 and 0.33 mg/mL respectively). The amounts of total phenolic and total flavonoid contents of the leaf extract were 141.56 mg Ga E/ 100 grams and 67.03 mg RE/ 100 grams of extract, respectively. Results of the phytochemical components had screening showed the absence of tannins, glycoside, triterpenes/steroids and saponins. Our findings suggest the possibility of using the leaves as a novel source of natural antioxidant agent for the pharmacology.
Intention, perception and trust: Comment on “Challenges of informed consent during a political crisis” by Mishra and Gaitonde
Authors: Srivatsan R
Published: July 2021

This note explores the relevance of the ethics requirement of having a “study­independent observer/impartial witness” signing off on the informed consent procedure when the community under study is unwilling to do so. It shows how the community's distrust of the researcher as an agent of a malevolent government (expressed in a refusal to sign the consent form) is reflected in the researcher's objective links to government through education and advanced academic research. The note argues that research ethics, rather than blindly following rules, means thinking about context. It reverses the question of relevance of the ethics protocol, to questioning the relevance of the research to the community. It suggests that thinking this through will clarify the position of the researcher and contribute to research ethics
Fighting the COVID-19 Infodemic in New articles and False Publications: NeoNet, a Text-based Supervised Machine Learning Algorithm
Authors: Abdeen Mohammad AR , Hamed Ahmed Abdeen , Wu Xindong
Published: July 2021

The spread of the Coronavirus pandemic has been accompanied by an infodemic. The false information that is embedded in the infodemic affects people’s ability to have access to safety information and follow proper procedures to mitigate the risks. This research aims to target the falsehood part of the infodemic, which prominently proliferates in news articles and false medical publications. Here, we present NeoNet, a novel supervised machine learning text mining algorithm that analyzes the content of a document (news article, a medical publication) and assigns a label to it. The algorithm is trained by TFIDF bigram features which contribute a network training model. The algorithm is tested on two different real-world datasets from the CBC news network and Covid-19 publications. In five different fold comparisons, the algorithm predicted a label of an article with a precision of 97-99 %. When compared with prominent algorithms such as Neural Networks, SVM, and Random Forests NeoNet surpassed them. The analysis highlighted the promise of NeoNet in detecting disputed online contents which may contribute negatively to the COVID-19 pandemic.
The Green Deal, National Energy and Climate Plans in Europe: Member States’ Compliance and Strategies
Authors: Maris Georgios , Flouros Floros
Published: July 2021

This paper analyses the EU’s policies for energy and climate, using Börzel's (2002) theoretical framework on Europeanisation, and examines member states’ Green Deal responses, strategies, and compliance. As expressed in their final NECPs, although member states’ responses vary, most of the critical components were partially addressed, while the others were largely addressed. We observe a considerable variation in Member State’s strategies. Member States classified as foot-dragging beforehand are fence-sitting now, while those previously categorised as fence-sitting are now either foot-dragging or pace-setting. The root cause of these classification changes for the member states within the EU can be traced back to their internal environments in which the involved stakeholders each have a different response pace regarding environment, climate, and energy. We present and analyse our theoretical context, discuss the EU’s energy policies and the NECPs, examine member states’ responses and compliance with this new framework, and propose several challenges.
Low-power ultra-small Edge AI Accelerators for Image Recognition with Convolution Neural Networks: Analysis and Future Directions
Authors: Lin Weison , Adetomi Adewale , Arslan Tughrul
Published: July 2021

Edge AI accelerators have been emerging as a solution for near customers’ applications in areas such as unmanned aerial vehicles (UAVs), image recognition sensors, wearable devices, robotics, and remote sensing satellites. These applications not only require meeting performance targets but also meeting strict reliability and resilience constraints due to operations in harsh and hostile environments. Numerous research articles have been proposed, but not all of these include full specifications. Most of these tend to compare their architecture with other existing CPUs, GPUs, or other reference research. This implies that the performance results of the articles are not comprehensive. Thus, this work lists the three key features in the specifications such as computation ability, power consumption, and the area size of prior art edge AI accelerators and the CGRA accelerators during the past few years to define and evaluate the low power ultra-small edge AI accelerators. We introduce the actual evaluation results showing the trend in edge AI accelerator design about key performance metrics to guide designers on the actual performance of existing edge AI accelerators’ capability and provide future design directions and trends for other applications with challenging constraints.
Epidemiological Surveillance of Eye Disease and People Awareness in the Abruzzo Region, Italy
Authors: Mastropasqua Leonardo , D'Aloisio Rossella , Mastrocola Alessandra , Perna Fabiana , Cerino Luca , Cerbara Loredana , Cruciani Filippo , Toto Lisa
Published: July 2021

Background and Objectives: Vision impairments and related blindness are major public health problems. Prevalence of eye disease and barriers to optimal care markedly vary among different geographic areas. In the Abruzzo region (Central Italy), an epidemiological surveillance on the state of ocular health in the population aged over 50 years was performed in 2019. Materials and Methods: Participants were sampled to be representative of the region inhabitants. Data were collected through a telephone interview and an eye examination. Prevalence of cataract, glaucoma, retinopathy, maculopathy was assessed. The Cohen’s kappa (k) was used to measure the agreement between presence of eye disease and awareness of the disease by the participants. Results: Overall, 983 people with mean age of 66.0±9.5 years were included in the study. The prevalence of cataract, glaucoma, maculopathy, and retinopathy was 52.6%, 5.3%, 5.6%, and 29.1%, respectively. Among the total of affected people, those aware of their condition were 21.8% (k=0.12, slight agreement) for cataract, 65.4% (k=0.78, substantial agreement) for glaucoma, 7.1% (k=0.10, slight agreement) for maculopathy, and 0% for retinopathy (k=-0.004, agreement lower than that expected by chance). Refractive defects were corrected in the vast majority of participants. Conclusion: In the Abruzzo region, about two third of citizens aged 50 years or over suffer from cataract, glaucoma, retinopathy or maculopathy, which are recognized as leading causes of blindness. Many people with eye disease do not know they have it. These data can be used by clinicians and policymakers to undertake clinical, political, and social actions.
The Impact of Diagnostic Ureteroscopy Prior to Radical Nephroureterectomy on Oncological Outcomes in Patients with Upper Tract Urothelial Carcinoma: A Comprehensive Systematic Review and Meta-analysis
Authors: Nowak Łukasz , Krajewski Wojciech , Chorbińska Joanna , Kiełb Paweł , Sut Michał , Moschini Marco , Teoh Jeremy Yuen-Chun , Mori Keiichiro , Giudice Francesco Del , Laukhtina Ekaterina , Lonati Chiara , Kaliszewski Krzysztof , Małkiewicz Bartosz , Szydełko Tomasz
Published: July 2021

Background: The incidence of intravesical recurrence (IVR) following radical nephroureterectomy (RNU) is reported in up to 50% of patients with upper tract urothelial carcinoma (UTUC). It was suggested that preoperative diagnostic ureteroscopy (URS) could increase the IVR rate after RNU, however, the available data are often conflicting. Thus, in this systematic review and meta-analysis we sought to synthesize that available data for the impact of pre-RNU URS for UTUC on IVR and other oncological outcomes; Materials and methods: A systematic literature search of the PubMed, Embase and Cochrane Library databases was performed in June 2020. Cumulative analyses of hazard ratios (HRs) and their corresponding 95% confidence intervals (CI) were conducted. The primary endpoint was intravesical recurrence-free survival (IVRFS), with the secondary endpoints being cancer-specific survival (CSS), overall survival (OS), and metastasis-free survival (MFS); Results: Among a total of 5489 patients included in the sixteen selected papers, 2387 (43.4%) underwent diagnostic URS before RNU and 3102 (56.6%) did not. Pre-RNU diagnostic URS was significantly associated with worse IVRFS after RNU (HR=1.44, 95% CI: 1.29-1.61, p<0.001) than RNU alone. However, subgroup analysis including patients without biopsy during URS revealed no significant impact of diagnostic URS on IVRFS (HR=1.28, 95% CI: 0.90-1.80, p=0.16). The results of other analyses showed no significant differences in CSS (HR=0.94, p=0.63), OS (HR: 0.94, p=0.56), and MFS (HR: 0.91, p=0.37) between patients who underwent URS before RNU and those who did not. Conclusions: The results of this meta-analysis confirm that diagnostic URS prior to RNU is significantly associated with worse IVRFS, albeit with no concurrent impact on the other long-term survival outcomes. Our results indicate that URS has a negative impact on IVRFS only when combined with endoscopic biopsy. Future studies are warranted to assess the role of immediate postoperative intravesical chemotherapy in patients undergoing biopsy during URS for suspected UTUC.
Improved Chinese Sentence Semantic Similarity Calculation Method Based on Multi-Feature Fusion
Authors: Liu Liqi ,   School of Automation, Beijing Institute of Technology 5 South Zhongguancun Street, Haidian District, Beijing 100081, China, Wang Qinglin , Li Yuan
Published: July 2021

In this paper, an improved long short-term memory (LSTM)-based deep neural network structure is proposed for learning variable-length Chinese sentence semantic similarities. Siamese LSTM, a sequence-insensitive deep neural network model, has a limited ability to capture the semantics of natural language because it has difficulty explaining semantic differences based on the differences in syntactic structures or word order in a sentence. Therefore, the proposed model integrates the syntactic component features of the words in the sentence into a word vector representation layer to express the syntactic structure information of the sentence and the interdependence between words. Moreover, a relative position embedding layer is introduced into the model, and the relative position of the words in the sentence is mapped to a high-dimensional space to capture the local position information of the words. With this model, a parallel structure is used to map two sentences into the same high-dimensional space to obtain a fixed-length sentence vector representation. After aggregation, the sentence similarity is computed in the output layer. Experiments with Chinese sentences show that the model can achieve good results in the calculation of the semantic similarity.