bluuebunny/crossref_metadata_2025 huggingface dataset:
Participants in the Elderly Empowerment Program Posyandu Ngudi Utomo: Study in Indonesia
Authors: Malik Abdul , Widhanarto Ghanis Putra , Vitriani Adhe Mella
Published: April 2020

Creating healthy, independent, quality and productive older adults can be performed through routine health care efforts, namely the need to pay attention to risk factors to improve the health of the elderly. This study aims to explain the process of empowering the elderly, explain the supporting and inhibiting factors in the process of allowing the elderly, and explain the outcomes of the elderly empowerment program through the posyandu. This qualitative study uses the subject of Posyandu management, posyandu’s cadres for elderly and elderly families. Data analysis is shown in an interactive model by describing complete description data. The results showed that the process of empowering the elderly starts from preparation, assessment, planning alternative programs, formulating action plans, implementation and evaluation; while supporting factors are enthusiastic elderly who are high enough to know the health and support of the elderly family. Awareness is still low even there is a lack of infrastructure. The implication of this research for the field of community empowerment studies is to provide the benefits of preliminary studies for the development of betterquality empowerment models.
Entrepreneurship Education for Family Investment Values in Indonesia and the Philippines
Authors: Husin Azizah , Yosef Yosef , Asuan Maria Elvira , Sumarni Sri , Surino Portio O , Dellomos Carl O
Published: April 2020

Education at home is preparing a child for the future even though parents educate their child without a specific goal. But the child gets the knowledge, value, skills, and habits of parental education with love and compassion. The purpose of this research is to know the entrepreneurial education conducted by parents to children in Indonesia and the Philippines. The study was conducted in Indonesia and the Philippines. The population of this research comes from university students in Indonesia and the Philippines. The research respondent is the first semester student to become a respondent, as it is still heavily influenced by family education, the spread of questionnaires using Google forms, where the intended student is 2019 class students to fill the form provided. The maximum sample amount is determined, 216 respondents were acquired for each country. Data analysis techniques use percentages, data is outlined based on the educational aspect given to students by parents in the family. Shows that parents in Indonesia and the Philippines have done their job well. Indonesia acquires higher average value than the Philippines for all components, namely: knowledge, values, habits, and entrepreneurial skills. Overall, it looks how much the average acquisition shows the difference in the results of Indonesia and the Philippines in educating future entrepreneurs by parents. Habituation in children through assignments to do something at home or homework. The value of skills educated by parents in the form of leadership values and the ability to network, communicate, and make decisions quickly. Entrepreneurship education can provide an intensive investment value as long as the child is still in the educational process of his parents at home.
The Transformation of Sustainable Community Empowerment Based on Islamic Boarding Schools System
Authors: Sudiapermana Elih , Muslikhah Muslikhah
Published: April 2020

Community empowerment and education are closely related to advancing society. The purpose of this study was to analyze the implementation and transformation of sustainable community empowerment based on Islamic boarding school system. This is due to the assumption that Islamic boarding school, as a sharia economic developer, gives several impacts on training entrepreneurship, independence of santri, and prosperity of the society. This research used a qualitative method with the phenomenological approach from Edmund Husserl. Phenomenology or transcendental phenomenology aims to find the existence of consciousness essence (intentionality) which consists of four awareness activities. The results of this study indicate that the community empowerment in Al-Ittifaw Islamic boarding school refers to environmental use. The school also adopts an experiential learning and learning by doing system. These systems accustomed the students to learn, maintain, and preserve nature. The agribusiness development of Al-Ittifaq Islamic Boarding School is based on INPEKBI (Divine, Domestic, Personal, Economic, Family, Passion, Ilmihi) principle. The conclusion of this paper is, several stages are needed in terms of raising awareness, habituation, and reinforcement to build the entrepreneurial spirit during the transformation of sustainable community empowerment based on Islamic boarding school system.
Optimization of Community Reading Garden Management in Improving Reading Culture
Authors: Septiarti Serafin Wisni , Tristanti Tristanti , Santi Fitta Ummaya
Published: April 2020

TBM is more accurately called a reading facility in the middle of the community (community-based library) and is managed simply, and independently by the community concerned. This action research aims to (1) describe the management pattern of Community Reading Gardens as part of Omah Passionaon empowerment programs; (2) Explain the optimization of TBM management in its efforts to improve reading culture. Action research with a focus on optimizing TBM management is carried out using a diagnosis, planning, implementing action and evaluation model with Omah Passinaon managers as research subjects. Data or information is collected by interviewing techniques such as FGDs, observations on aspects of program management, activities to obtain a comprehensive picture of the potential, problems, needs for improvement and forms of action to optimize TBM management. The results of this study indicate that (1) TBM management emphasizes the competence of capable and skilled managers in building public awareness of the importance of reading culture, as well as the realization of TBM that has community appeal as a source of information in Bejiharjo tourism area. (2) Actions for optimizing TBM management in research include (a) Raising public awareness of reading fondness at Omah Passionaon, (b) partnerships with academics, universities, and private parties, (c) mentoring for pioneering TBMs that attract public interest in reading, (d) evaluation. TBM management can be effective must have partnerships from private or government institutions, besides that the manager also has good competence. The benefit of this research is to provide awareness to the community to read and motivation for TBM managers to seek partnerships with private and government institutions.
Effect of Flippeed Classroom Models and Creative Thinking of Science Literation Students
Authors: Susanti Wiwi , Supena Asep , Cahyana Ucu
Published: April 2020

The flipped classroom model, which is often heard in recent years, is known as a new pedagogical approach in which traditional instruction is reversed. The study aims to determine the effect of the flipped classroom model and creative thinking on the scientific literacy of grade VI students of SDN Guntur 01, South Jakarta. This research uses a 2x2 factorial design. The research sample was divided into two treatment groups, namely the experimental class and the control class. The experimental class was given treatment by carrying out the learning model of the flipped classroom , while the control class was given treatment by carrying out the expository model learning. The results showed: (1) there was a difference in scientific literacy between the experimental class and the control class, with scientific literacy higher than the control class.  (2) there is a difference in scientific literacy between groups of students with high levels of creative thinking in the experimental class [A 1 B 1 ] and the control class [A 2 B 1 ]. (3) there is a difference in scientific literacy between groups of students with low creative thinking levels in the experimental class [A 1 B 2 ] and the control class [A 2 B 2 ].  (4) there is an effect of interaction between learning models and creative thinking on scientific literacy. Purpose of the flipped classroom model is to use face to face time more effectively in the learning process. There are many definitions related to flipped classroom is a student-centred learning method consisting of two parts with interactive learning activities during lesson and individual teaching based on computer out of lesson.
Implementation of Parenting Education in Early Childhood Education Institutions
Authors: Baroroh Siti Arini , Budiartati Emmy , Fakhruddin Fakhruddin
Published: April 2020

One of the successes of early childhood education is the involvement of parents in their children’s education. Parenting education is one aspect of achieving these educational goals. The purpose of this study is to describe the implementation of parenting education in Pendidikan Anak Usia Dini Institutions as well as supporting and inhibiting factors in the application of parenting education. This research uses a qualitative research approach. Data collection methods used are interviews, observation, and documentation. Research subjects were conducted on 6 parents of students and 3 informants, namely educators and educational staff. The validity of the data uses triangulation techniques and uses qualitative data analysis. The results showed that parenting education has programmed planning to start from the implementation objectives, implementing organizations to competent resource persons, but has not paid attention to the reference in its implementation and has not identified the needs of parents in planning activities. Parenting education is carried out in various forms of routine and incidental activities. Supporting factors are the commitment of educators and parents in running the program, the availability of adequate facilities and infrastructure. Inhibiting factors are low parenting awareness and busy working parents resulting in low involvement in activities. Parenting education is very important for a better child’s life, for that there needs to be good management in every early childhood education.
Impact of the Work Environment and Work Motivation in Influencing the Performance of Non-Formal Educators
Authors: Djibu Rusdin , Duludu Ummyssalam
Published: April 2020

Work Environment and Work Motivation can affect performance in an institution, institution or company. For that, a leader needs to think about it. The purpose of this study was to determine: (1) the influence of the work environment with the performance of Non-formal Educators on the Development Center for Early Childhood Education and Gorontalo Community Education, (2) the effect of work motivation on the performance of Non-Formal Educators at the Center for Early Childhood Education Development and Gorontalo Society Education. (3) the influence of the work environment and work motivation together with the performance of Nonformal Educators for the Development of Early Childhood Education and Gorontalo Community Education. The method used in this research is to use quantitative through remorse techniques to express one variable to another. The population in this study were non-formal educators at the Gorontalo Center for Early Childhood Education and Community Education, which collected 80 people while the sample was a population sample. Data collected through questionnaire distribution. The conclusions of this study are (1) Providing a positive influence on the performance of Non-formal Educators for the Development of Early Childhood Education and Gorontalo Society Education, providing improved environmental performance with the performance of non-formal educators. (2) Providing positive motivation for the performance of Non-formal Educators for the Development of Early Childhood Education and Gorontalo Community Education, providing good motivation for improving the performance of Non-Formal Educators. (3) Making a positive contribution to the work environment and work motivation together to the performance of Non-formal Educators for the Development of Early Childhood Education and Gorontalo Community Education, this means improving the work environment and encouraging work and then improving the performance of Non-formal Educators. The novelty of the research is the performance of Non-formal Educators will be more effective if a leader always provides work motivation regularly and makes a conducive work environment. This research provides knowledge to leaders in improving the performance of Non-formal Educators or teachers, needing to pay attention to motivation and work environment within an institution or company.
Application of Arduino-Based Systems as Monitoring Tools in Indoor Comfort Studies: A Bibliometric Analysis
Authors: Daniel Trento  , Ticiana Patel Weiss Trento  , Eduardo Krüger
Published: April 2020

Studies that require environmental measurements often struggle with the cost of monitoring equipment. Costs will increase as more variables are required. Thus, scientists have been increasingly relying on Arduino systems to overcome such a challenge. This paper aims to review the literature on the use of Arduino as a viable measurement tool in indoor comfort research. For this purpose, the results from three databases were compared: Web of Science, Scopus and ScienceDirect. Results from the Scopus search were then analyzed using VOSViewer according to three questions: (1) what is the state of the art and trends using Arduino; (2) how is Arduino being used in indoor environments; and (3) which are the main authors using the system and what are the most cited Arduino-related sources. The maps showed that the system is very versatile and offers the opportunity to strengthen multidisciplinary approaches.
Experimental Study on Pyrolysis of Non-Metallic Materials Separated from Printed Circuit Board Waste via TGA and Analytical Vacuum Fast Pyrolysis of Non-Metallic Fraction of Printed Circuit Board Waste after Copper Separation
Authors: Songpol Boonsawat  , Qiming Jimmy Yu  , Erik L.J. Bohez  , Soon Chia
Published: April 2020

In just over half a century electronic equipment and products have revolutionized human lifestyle. At the product’s end of life, e-waste, its components material and other materials have influenced and infiltrated environment in every part of globe. The hazardous effect of plastic materials and debris to biodiversity is well established, but mitigation and planning are often hampered by lack of quantitative data on waste accumulation patterns in landfill. Here we document a study on the pyrolysis of non-metallic material of printed circuit board, the basic elemental part of electronic waste. The non-metallic material is separated from printed circuit board waste during the copper separation processes and was found in powder form at average size up to 177 μm. The purpose of this study is to experimentally investigate the pyrolysis behavior of the non metallic material of printed circuit boards (PCB) waste fraction at a temperature range of 300 ◦C to 600 ◦C by means of the Thermogravimetric Analysis (TGA) and seek to find out the effective pyrolysis temperature that could be used in pyrolysis process in production scale. The experimental results reveal that the chemical composition of the PCB reflects that the main decomposition of PCBs occurs between 250 ◦C and 450 ◦C, and effectively decomposed at 403 ◦C. The pyrolysis of PCBs showed a varying production of aromatic compounds such as phenol, bromophenol, styrene, methylstyrene, and bisphenol A as well as non-aromatic compounds such as acetone and bromomethane, which are strongly related with the initial chemical composition of PCBs.
“That’s the Spiritual Side of Me”
Authors: Rodriguez-Morales Lymarie
Published: April 2020

This study explores young adult men's lived experience of addiction recovery through their involvement in Twelve Step fellowships' spirituality. Although there is a large body of research on Twelve Step's recovery model, few studies have examined young adult men's psychological and identity transformation in light of its spiritual principles. Ten men participating in Twelve Step fellowships in the UK were recruited and invited to write a topical autobiography of their recovery. Data were analysed using interpretative phenomenological analysis. Participants in early recovery (six months to two years in recovery) provided accounts mostly concerned with maintaining abstinence and incorporating the Twelve Step spiritual principles and practices into their lives. Participants in long-term recovery (five to ten years) portrayed "personal growth" narratives, reflecting on their involvement with the fellowships through their life-course. Values of belonging, authenticity, care and love were identified as significant themes in their narratives and continue to infuse their identities long after initial sobriety establishment. The findings suggest that participants' spirituality evolves into a loving and caring masculine identity, which is key to their psychological development into mature adulthood. It is suggested that amidst the variety of spiritual recovery experiences (religious, atheist or secular) within the Twelve Step programmes, members share life-enhancing values that support the transcendence of their addiction.
Yukon First Nation use of Copper for End-Blades on Hunting Arrows
Authors: Thomas Christian Daniel , Hare P. Gregory , Reuther Joshua D. , Rogers Jason S. , Cooper H. Kory , Dixon E. James
Published: April 2020

Copper metallurgy and bow and arrow technology are widely considered hallmark traits of the Late Prehistoric Period in the northwest of North America (Yukon and Alaska). In recent years, a number of osseous arrow points have been recovered from melting alpine ice patches in the northwest, some with evidence of copper utilization. This article reports on the construction and radiocarbon dating of three osseous arrowheads recovered from Yukon-Alaska ice patches and documents the use of handheld energy-dispersive x-ray florescence (EDXRF) technology to discriminate native copper implements, as well as detect absorbed copper residues from other osseous points. We also reference several other bladed arrow points discovered at ice patches in Yukon and neighboring Alaska to develop a tentative timeline for the use of copper end-blades with osseous arrow points in the northwest.
Investigation of The Synergistic Effects of Trastuzumab And Gambogic Acid in Her-2 Positive Breast Cancer Cell Line
Authors: ÇETİN Ahmet , ÖZGÜR Aykut , KUZUCU Mehmet , ÇANKAYA Murat
Published: April 2020

HER2 positive breast cancer is one of the biggest health problems in the world, causing millions of deaths every year. Drug combination modeling studies are extensively evaluated in treating many diseases. Pharmacological studies over the last half-century have shown that gambogic acid has potent anti-tumor activity against many types of cancer, including breast cancer. In this study, we examined the synergistic anticancer effect of gambogic acid and trastuzumab in HER2 positive breast cancer cell line (MDA-MB-453). In-vitro synergistic and antiproliferative effects of trastuzumab plus gambogic acid studies were determined with XTT method and the combination index (CI) values of the trastuzumab and gambogic acid combination were calculated by CompuSyn software. To determine molecular mechanisms of the trastuzumab and gambogic acid combination, we analyzed HER2, caspase-9 and Bax gene and protein expression levels quantitative reverse transcription-PCR (qRT-PCR) and ELISA techniques. The combination of 50 µg/ml trastuzumab and 5 µM gambogic acid showed the best synergistic effect at 24 h incubation in MDA-MB-453 cells according to the in-vitro cell proliferation, RT-qPCR and ELISA test. Gambogic acid effects on HER2 positive breast cancer cell line shows its potential as natural compound to inhibit breast cancer cell proliferation in combination with trastuzumab.
Emergency science: epistemological insights on the response to COVID-19 pandemics
Authors: Fortaleza Carlos Magno
Published: April 2020

The response to the current COVID-19 pandemics require reflections on the validity of scientific knowledge. While non-pharmacological measures for disease control are providing a worldwide natural experiment, it is highly advised to submit research findings to the scrutinity of renowed epistemologic theories. One should also consider the loosening of methodological criticism in time when diffusion of results is urgently required. Though criticism is perhaps most precious principle of scientific thinking and practice, scientists must find a way into relative consensus that can be translated into public health policies.
RESPOSTAS DOS MUNICÍPIOS PARA GARANTIR SEGURANÇA ALIMENTAR E NUTRICIONAL EM TEMPO DE PANDEMIA
Authors: Borsatto Ricardo , Grigoletto Fábio , Macedo André de Camargo , Martensen Alexandre Camargo
Published: April 2020

Nesse texto, nosso objetivo foi o de demonstrar que municípios podem e devem desenvolver ações locais com vistas a garantir a Segurança Alimentar e Nutricional (SAN) de seus munícipes em tempo de pandemia. O processo de descentralização do pacto federativo incentivado pela Constituição Federal de 1988 e o aprendizado institucional derivado da implementação local de políticas federais de SAN ocorrido a partir de meados da década de 2000 ofereceram condições estruturantes para os municípios assumirem maior protagonismo nesta área. Identificamos mecanismos e estratégias intramunicipais e intermunicipais com potencial aplicação direta em outros municípios com perfis similares aos municípios estudados. Tais aplicações podem levar a respostas positivas a iminente crise de SAN intensificada pela COVID-19.
Assessing and Addressing the Need for Cancer Patient Education in a Resource-Limited Setting in Haiti
Authors: Schleimer Lauren E. , Desameau Peter-Gens , Damuse Ruth , Olsen Maia , Manzo Veronica , Cardenas Carlos , Mehrtash Hedieh , Krakauer Eric L. , Masamba Leo , Wang Catharine , Bhatt Ami S. , Shulman Lawrence N. , Huang Franklin W.
Published: April 2020

Purpose

Misinformation and lack of information about cancer and its treatment pose significant challenges to delivering cancer care in resource-limited settings and may undermine patient engagement in care. We aimed to investigate patients’ knowledge and attitudes toward cancer and its treatment and to adapt, implement, and evaluate a low-literacy cancer patient education booklet at the Hôpital Universitaire de Mirebalais (HUM) in rural Haiti.

Materials and Methods

A low-literacy cancer patient education booklet was adapted into Haitian Creole in collaboration with clinicians at HUM. Patients were recruited for structured interviews (n = 20) and two focus groups (n = 13) designed to explore patients’ attitudes toward cancer and its treatment and to assess whether the booklet increased patients’ knowledge via an investigator-designed knowledge test.

Results

Participants reported a subjective lack of knowledge about cancer and its treatments and described views of cancer as deadly or incurable. Patients of varying education levels valued receiving written materials that set expectations about cancer treatment and expressed a desire to share the booklet with caregivers and others in their community. Participants across all levels of education significantly increased their performance on a knowledge test after counseling using the booklet (p < .001).

Conclusion

We found that an educational booklet about cancer developed in collaboration with local providers was well received by patients with variable literacy levels and improved their knowledge of cancer and its treatment in a resource-limited setting. Such educational materials have the potential to serve as tools to engage patients with cancer and their families in care.

Implications for Practice

Misinformation and lack of information pose significant challenges to delivering cancer care in resource-limited settings; however, there are often no culturally and literacy appropriate tools available to aid in patient education. This article shows that written educational materials are well received by patients of variable literacy levels and can be effective tools for increasing patients’ knowledge of cancer and its treatment in a limited-resource setting. Furthermore, the authors have made their educational booklet, Cancer and You, freely available online and welcome the opportunity to connect with readers of The Oncologist interested in implementing this educational booklet in clinical care.
Oncology in 2050 – A Retrospective?
Authors: Joshua Anthony M. , Tannock Ian F.
Published: April 2020

This fictional narrative from the year 2050 presents a potential retrospective view of progress in oncology
Multiple Myeloma Incidence and Mortality Around the Globe; Interrelations Between Health Access and Quality, Economic Resources, and Patient Empowerment
Authors: Ludwig Heinz , Novis Durie Susie , Meckl Angela , Hinke Axel , Durie Brian
Published: April 2020

Background

The interrelation between the worldwide incidence, mortality, and survival of patients with multiple myeloma (MM) and relevant factors such as Health Care Access and Quality (HAQ) index, gross domestic product (GDP), health care expenditures, access to cancer drugs, and patient empowerment has not been addressed before.

Material and Methods

Epidemiologic data were obtained from the International Agency for Research on Cancer. The mortality-to-incidence ratio (expressed as 1-MIR) was used as proxy for 5-year survival. Information on health expenditure was obtained from Bloomberg Health-Care Efficacy ranking, the HAQ Index was used as a measure of available health care. For patient empowerment, visits to the Web site of the International Myeloma Foundation were used as proxy. Data on GDP and population per country were assessed from the International Monetary Fund and the United Nations Population Division, respectively. Possible associations were analyzed using Spearman's rank-order correlation.

Results

The worldwide incidence of MM is currently 160,000, and mortality is 106,000. Age-standardized myeloma incidence varies between 0.54 and 5.3 per 100,000 and correlates with 1-MIR, patient empowerment, HAQ Index, and access to cancer drugs. The 1-MIR varies between 9% and 64% and is closely related to myeloma incidence, HAQ Index, patient empowerment, access to cancer drugs, and health care expenditures.

Conclusion

The global incidence and outcome of MM shows significant disparities, indicating under-recognition and suboptimal treatment in many parts of the globe. Results also highlight the importance of economic resources, access to and quality of health care, and patient education for improving diagnosis and survival of patients with MM.

Implications for Practice

Multiple myeloma accounts for 10% of all hematological malignancies and has moved to the forefront of clinical interest because of the significant advances in medical treatment. Diagnosis depends on laboratory tests, imaging, and professional expertise, particularly in patients without a significant M-component. The present data show a substantial worldwide variation in incidence and mortality, that is mainly due (apart from variations due to ethnicity and lifestyle) to disparities in access to and quality of health care, a parameter strongly related to the economic development of individual countries. Improvement of quality of care and, consequently, in outcome is associated with patient empowerment.
El ve El bilek yumuşak doku tümörlü hastalarda eksizyonel cerrahi kısa dönem sonuçları
Authors: ACAR Erdinç , GÜLTEKİN Alper
Published: April 2020

Amaç:
El ve el bilekte yumuşak doku kitlesi ile kliniğimize başvurup eksizyonel
cerrahi tedavi uyguladığımız hastaların kısa dönem sonuçları değerlendirildi.

Gereç ve Yöntem:
Çalışmaya, Aralık 2017 ile Mayıs 2019 tarihleri arasında eksizyonel cerrahi
tedavi uygulanan 34 hasta (25 bayan, 9 erkek) dahil edildi. Bu hastaların
ameliyat sonrası patoloji sonuçlarında; 20 hastada ganglion kisti, 6 hastada
epidermal inklüzyon kisti, 4 hastada tendon kılıfı dev hücreli tümör, 2 hastada
lipom, 1 hastada hemanjiom ve 1 hastada düşük dereceli (low grade) liposarkom  şeklinde sonuç alındı. Bu hastalarda yineleme
oranı ve mennuniyet oranları değerlendirildi. Cerrahi sonrası yara yeri
enfeksiyonu ve nörovasküler yaralanma gibi komplikasyonlar değerlendirilmiştir.

Bulgular:
Hastaların yaş ortalaması 42,6 (29-57). Hastaların 25’i (%73,6) bayan, 9’u
(%26,4) erkek idi. Hastalar ortalama 13 ay (10-18) takip edildi. Hastalarda
yineleme izlenmedi. Hastaların tamamı, cerrahi tedaviden memnun kaldıklarını
belirtti.

Sonuç:
El ve el bilek yumuşak doku tümörü olan hastalarda uygulanan düzgün ve başarılı
eksizyonel cerrahi tedavi; nüks ve komplikasyon gelişmemesi açısından yararlı bir
yöntem olarak karşımıza çıkmaktadır.Introduction:
In this study,
we report our short-term results of excisional surgery in patients with soft
tissue tumors of the hand and wrist.Methods:
A total of 34
patients who were admitted with a soft tissue lesion of the hand and wrist and
underwent excisional surgery in our clinic between December 2017 and May 2019
were included. Pathological examination results were reported as a ganglion cyst
in 20, an epidermal inclusion cyst in six, a giant cell tumor of tendon sheath
in four, a lipoma in two, a hemangioma in one, and a low-grade liposarcoma in
one patient. Recurrence rate and patient satisfaction were evaluated.
Postoperative complications such as wound infections and neurovascular events
were recorded.Results:
Of the patients,
25 (73.6%) were females and 9 (26.4%) were males. The mean age was 42.6 (range,
29 to 57) years. The mean follow-up was 13 (range, 10 to 18) months. No recurrence
was seen in any of the patients. The rate of patient satisfaction was 100% in
all patients.Discussion
and Conclusion: Our study
results suggest that a well-planned excisional surgery is an effective and
feasible method for the treatment of soft tissue tumors of the hand and wrist
and has no potential risk for recurrence or postoperative complications.
ELEKTİF TOTAL ABDOMİNAL HİSTEREKTOMİ VE BİLATERAL OOFEREKTOMİ YAPILAN HASTALARDA İNTRAOPERATİF FARKLI DOZLARDA UYGULANAN LİDOKAİN İNFÜZYONUN POSTOPERATİF AĞRI KONTROLÜNE VE ANALJEZİ TÜKETİMİNE ETKİLERİNİN GÖZLENMESİ
Authors: GÜL Dudu , ALKAYA SOLMAZ Filiz , KIRDEMİR Pakize
Published: April 2020

Çalışmanın amacı, peroperatif farklı dozlarda uygulanan lidokain infüzyonunun postoperatif analjezi ihtiyacına etkilerini, postoperatif bulantıya ve toplam parasetamol tüketimine etkilerini araştırmak.
Bu çalışmada operasyon süresi 120 dk’ı geçmeyen elektif şartlarda TAH-BSO operasyonu geçiren ve peroperatif lidokain infüzyonu yapılan hastaların medikal ve anestezi kayıtları retrospektif olarak değerlendirildi. 18-65 yaş arası, ASA I-II, VKİ <25 olan hastalar çalışmaya dahil edildi. Dosya kayıtları incelenen hastalar 3 gruba ayrıldı; Grup L1: 1.5 mg/kg lidokain infüzyon yapılan hastalar, Grup L2: 3 mg/kg lidokain infüzyon yapılan hastalar ve Grup S: sadece SF infüzyon yapılan hastalar. Değerlendirilen dosyalardan 3 mg/kg/h lidokain infüzyonu yapılan 3 hastada bradikardi geliştiği için lidokain infüzyonunun kesildiği saptandı ve çalışma dışı bırakıldı. Hastaların anestezi takip fişlerinden hemodinamik parametreler, demografik veriler, algoloji takip formlarından postoperatif VAS skorları, bulantı, ilk mobilizasyon zamanı ve toplam parasetamol tüketimi kaydedildi.
Demografik ve hemodinamik veriler açısından gruplar arasında fark bulunmadı. Postoperatif 2, 6 ve 14. saat VAS değerleri Grup L1’de Grup S’e göre anlamlı olarak daha düşük bulundu (p<0,001). Hastaların postoperatif 6, 10 ve 14. saatteki bulantısı Grup S’de diğer gruplara göre anlamlı olarak daha yüksek bulundu (p<0.05). İlk analjezi zamanlarına bakıldığında da Grup L1’de Grup S’e göre ilk parasetamol zamanı anlamlı olarak daha geç bulundu (p=0.008).
Sonuç olarak 3 mg/kg lidokain infüzyonun postopeartif VAS skorlarını düşürdüğünü ancak bradikardi yapma olasılığının olduğunu, 1.5 mg/kg lidokain infüzyon dozlarının postoperatif analjezik etki sağladığını ve yan etki insidansını da azalttığını düşünmekteyiz
Safety and cost-effectiveness of screening for atrial fibrillation in a single primary care center at a three- year follow-up v1
Authors: Ghazal Faris
Published: April 2020

Aims The aim of this study was to estimate the cost-effectiveness of intermittent electrocardiogram (ECG) screening for atrial fibrillation (AF) among 70–74-year old individuals in primary care. We also aimed to assess adherence to anticoagulants, severe bleeding, stroke and mortality among screening-detected AF cases at three-year follow-up. Methods A cohort population, based on a cross-sectional screening study for AF among 70–74-year old patients, who were registered at asingle primary care center, was followed for three years for mortality. Data about adherence to anticoagulants, incidence of stroke and severe bleeding among screening-detected AF cases, were collected from patient’s records. Markov model and Monte Carlo simulation was used to assess the cost-effectiveness of thescreening programme. Results The mortality rate among screening-detected AF cases (n=16) did not differ comparedto the 274 individuals with no AF (hazardratio 0.86, CI 0.12-6.44). Adherence to anticoagulants was 92%. There was no stroke or severe bleeding. The incremental cost-effectiveness ratio of screening versus no screening was EUR 2,389/Quality-adjusted life year (QALY) gained. The screening showed a 99% probability of being cost-effective compared to no screening at a willingness-to-pay threshold of EUR 20,000 pe rQALY. Conclusion Screening for AF among 70–74-year olds in primary care using intermittent ECG appears to be cost-effective. This screening also appears to be safe at three-year follow-up with high anticoagulants adherence and no increasedmortality.
Homeopathic Approach to COVID-19: A Review
Authors: Hasan Nazmul , Nayem Mesbah Uddin Md. Rezwanun , Mohshinuzzaman Mohammad , Biswas Anwar H , Kayes Md. Emrul , Hakim Md. Abdul , Uddin Nizam , Alom Md. Jahangir
Published: April 2020

Novel coronavirus 2019-nCoV-2 infection, also known as COVID-19, has a pandemic outbreak, and recent studies show various limitations, including treatment. This virus is chiefly infecting the respiratory tract (RTI) and resulting in Severe Acute Respiratory Syndrome. Many developed countries, including Italy, England, and the United States of America (USA), are facing many casualties. Unlikely, no specific treatment protocol is available till today. Homeopathic medicine is a branch of alternative medicine, practiced on individualized symptoms similarity. However, historically it has potential in treating epidemic infections like scarlet fever, typhoid, and cholera. In the treatment of RTI and pneumonia, several homeopathic medicines have proven efficacy. This review on the utility of homeopathic medicine might guide the physician to prevent COVID-19 contagion. Homeopathic medicines can help humanity with conventional medical methods to prevent this global catastrophe.
EDITORIAL - Los procesos de enseñanza y aprendizaje
Authors: Sánchez-Cabrera Samuel Alberto
Published: April 2020

Los procesos de enseñanza y aprendizaje en la Universidad tienen como referencia fundamental el Proyectos Educativo Institucional, los lineamientos curriculares y el modelo pedagógico; orientadores de la gestión del currículo en relación con la docencia, la investigación y la proyección social; facilitando los aprendizajes de comunidades aprendientes como generadores de dinámicas de vida que propenden por el bienestar colectivo.
Cord blood spot thyroid stimulating hormone for screening of congenital hypothyroidism
Authors: E. Narayanan , Seeralar Arasar
Published: April 2020

Background: Congenital hypothyroidism is one of the most common causes of mental retardation in pediatric age group. Screening for congenital hypothyroidism is one of most cost effective tools to prevent mental retardation among the general population. Umblical cord TSH estimation remains an easily available option for screening of congenital hypothyroidism. Aims and objectives was to estimate correlation between TSH obtained from cord blood TSH and heel prick TSH at 3rd day of life using blood spot. To estimate the predictability to rule out congenital hypothyroidism using cord blood spot TSH and to determine whether cord blood TSH can be advocated to screen congenital hypothyroidism.Methods: Prospective study conducted in department of Neonatology, IOG, Egmore after obtaining consent from parents. The study was carried out in two phases. First phase, to establish correlation between cord blood spot TSH and heel prick TSH and to establish median cutoff point of TSH .Second phase, to establish cord blood spot TSH as screening method.Results: The birth weights ranged between 2.5 to 4.3 kg. TSH values ranged from 2.0-33.3mlU/L. The mean value was 16.45mlU/L. A cutoff value of 20mlU/L was used for recall testing of complete thyroid profile (T3, T4 and TSH). Thirty six infants were recalled for repeating complete thyroid profile.Conclusions: Congenital hypothyroidism (CH) is the one of the most common preventable causes of mental retardation which can be detected by measuring cord blood TSH .Cord blood TSH can be advocated in national public health program as a routine so that all babies can be tested before discharge thereby minimising interventions for the baby.
Amniotic band syndrome: a case series
Authors: Singh Vinaya A. , Desai Navina V. , Malik Sushma , Wade Poonam , Gandhi Prachi
Published: April 2020

Amniotic band syndrome (ABS) is a rare congenital disorder which involves fetal entrapment in strands of amniotic tissue, which can manifest as constriction rings, limb and digital amputations or complex congenital anomalies and sometimes results in stillbirth. Etiopathogenesis is varied and ABS can be associated with syndromes. Antenatal diagnosis is made by ultrasonography in most cases. Postnatal examination reveals constrictions, amputations and craniofacial or abdominal wall defects. Treatment is case based and surgical intervention is required to release constriction rings. Authors report here six cases (one stillbirth and five live births) of amniotic band syndrome that were encountered over the last one and half years.
A randomised controlled trial on effect of splinting a joint on the lifespan of intravenous cannula in pediatric patients
Authors: H. Murali B. , Chandrasekaran Abirami Meenakshi , Nannapaneni Meghana
Published: April 2020

Background: Children admitted to hospital and ICUs for various reasons like sepsis, respiratory distress, dehydration, shock etc. require an intravenous line for medications and IV fluids. Properly securing an intravenous line is very important. It is equally important to maintain the patency of the intravenous line for longer periods of time. But there is no adequate data regarding factors affecting the duration of patency of an IV line. This study was done to compare effect of limb splinting versus non-splinting with the functional duration of peripheral IV cannula.Methods: This study was done over 3 months between October - December 2018 in pediatric patients (age 6 months to 5 years) admitted to Kempegowda Hospital. Patients were randomised into splint group and non-splint group. In the splint group a firm splint was applied to the joint that was cannulated. No such intervention was done in the non-splint group. Time from IV line placement to removal was measured.Results: Total 438 patients were taken into study. After exclusion 200 patients were given a splint and 200 were not splinted. The median survival time was more in splint group when compared to non-splint group.Conclusions: This study shows that splinting helps to maintain patency of IV line for a more longer duration than non splinting of the joint.
Maternal hypothyroidism and neonatal outcome
Authors: Pai Hrishikesh S. , Joy Rojo , Cherian Varghese , Peter Preethy
Published: April 2020

Background: Hypothyroidism is widely prevalent in pregnant women but rate of detection is very low in developing countries. Hypothyroidism is easily treated, timely detection and treatment of the disorder could reduce the burden of adverse fetal and maternal outcomes. Objective of the study was to determine the immediate outcome in neonates born to mother with hypothyroidism.Methods: Prospective descriptive study.110 babies were observed for neonatal outcome.55 babies were born to hypothyroid mothers and 55 babies were born to mothers without thyroid abnormalities. These babies were observed for type of delivery, Gestational age, need for intensive care unit, growth parameters, Interventions required during the stay, sepsis was compared with those born to mothers without hypothyroidism.Results: Both the groups were similar in terms of type of delivery. No association between maternal hypothyroidism and Hypertensive disorders, gestational diabetes. Cases with prematurity are almost same in both groups. Most of babies were term gestation. The birth weight of babies was similar. Majority from both the group did not require any oxygen support. Majority of babies were in appropriate for age category. Both the groups were similar in incidence of small for gestational age and large of gestational age babies.Conclusions: Babies born to well treated hypothyroid mothers were similar in all aspects to babies born to non-hypothyroid mothers. These signify the importance of screening all antenatal mothers for hypothyroidism and prompt treatment to prevent adverse consequences on neonatal outcome.
A rare case of Kunze-Riehm syndrome in a neonate
Authors: S. Venugopal , Devadas Sahana , M. Yashwant
Published: April 2020

The Kunze-Riehm syndrome also called as Michelin tire baby syndrome (MTBS), is a rare genodermatosis, characterized by multiple symmetric circumferential folding of excess skin with the various phenotypic abnormality. The diagnosis is made on the basis of the characteristic clinical features in the literature there are approximately 31 cases reported and to the best of our knowledge, this would be the sixth case published from India. Herein authors report a rare case of Kunze- Riehm syndrome in a neonate.
Non-immune hydrops fetalis: a case series
Authors: Das Niladri , Malik Sushma , Gandhi Prachi , Singh Vinaya A. , Wade Poonam
Published: April 2020

Hydrops fetalis is a clinical condition characterized by pathological fluid accumulation in soft tissues and serous cavities of the fetus like peritoneal cavity, pleural cavity, pericardial space, and body wall edema. Hydrops fetalis is broadly classified into Immune Hydrops Fetalis (IHF) and Non-Immune Hydrops Fetalis (NIHF). Incidence of immune hydrops fetalis due to Erythroblastosis fetalis secondary to Rh Iso-immunisation has drastically reduced due to widespread use of anti-D immunoglobulin. In the last few decades, the majority of cases are identified as non-immune hydrops. It is important to determine the cause of the hydrops fetalis in order to administer optimal management of the neonate at birth. Despite recent advances the mortality of non-immune hydrops is still high. Authors report here six cases of non-immune hydrops fetalis encountered at our tertiary care hospital over last three years.
A five-year study of Influenza A (H1N1) pandemic 09 from Central India
Authors: Shendre Pooja , Raut Sharmila , Khadse Ravindra
Published: April 2020

Influenza virus is a typical human pathogen causing serious respiratory infection. While declaring the last pandemic to be over in August 2010, World Health Organisation (WHO) conveyed that Pandemic Influenza A (HINI) virus would circulate as Seasonal Influenza virus for years to come. This study was undertaken to observe trends of Influenza A (H1N1) pandemic 09 over last five years in Vidarbha region of Maharashtra.

Throat/nasal/nasopharyngeal swabs/aspirates from clinically suspected cases of influenza like illness in category C received in the Viral Research and Diagnostic Lab (VRDL), Indira Gandhi Govt Medical College (IGGMC), Nagpur from October 2015 to September 2019 were included in the study. The samples were tested by reverse transcriptase real time polymerase chain reaction (RT-PCR). Clinical and epidemiological parameters were also noted.

Inﬂuenza A(H1N1)pandemic 09 positivity ranged from 03% to 21% in last five years. Males and females were almost equally affected except in 2019. Maximum positive cases were seen in age group of 41-60 years in 2015 (24%), 0-10 years in 2017(24%), 21-40 years in 2018 (9%) and 11-20 years (26%) in 2019 . Dual peaks of infection were seen in 2017, 2018 and 2019. Bhandara, Gondia and Akola districts had highest positivity .

Inﬂuenza A(H1N1)pandemic 09 is showing shift towards younger age groups and females slightly, both of which needs attention. Waning and waxing trend in last five years indicate unpredictable and changing epidemiology of the virus which should be studied further in details with respect to time, place, person and molecular characterisation of the virus.
Study of prevalence Rifampicin and/ or Isoniazid drug resistance among newly diagnosed cases of sputum smear positive pulmonary tuberculosis at tertiary care centre
Authors: Dilip Muley Sushant , Meshram Sushant , Yadav Ravi , Naeem Tauseef , Gandhare Avinash
Published: April 2020

Worldwide tuberculosis is most common infectious cause of death. India bears one-fourth of the global tuberculosis burden. Despite all national & international efforts to control & eliminate tuberculosis, more than 10 million active tuberculosis cases occur each year. The problem of tuberculosis has been further compounded by the emergence of multi drug resistant (MDR) and extensively drug resistant(XDR) tuberculosis. Previously treated tuberculosis is most important risk factor for drug resistant TB but treatment naïve patients are also at risk due to transmission of drug resistant strain or spontaneous mutation.

Study was conducted in Department Of Respiratory Medicine, GMC Nagpur between May 2017 to October 2018.It was prospective observational study. All sputum smear positive cases were subjected to mycobacterial culture and LPA testing in IRL.

Total 250 patients whose sputum smear was positive for acid fast bacilli were included in study. Maximum patients were in age group of 18-30 years of age with mean age 36.43+/-14.05.Out of 250 patient 188 were males and 62 were females. Isoniazid monoresistance was found in 6 patients and isoniazid with rifampicin resistance was found in 9 patients. We did not find any case of rifampicin monoresistance in our study.

Prevalence of isoniazid monoresistance was 2.4 % in our study while prevalence of isoniazid and rifampicin resistance (MDR TB) was 3.6%. Thus prevalence of drug resistant TB is low amongst newly diagnosed sputum smear positive cases. This shows success of tuberculosis control programme.