bluuebunny/crossref_metadata_2025 huggingface dataset:
Case Study: RTU on the Way to Participate in Race to Zero Challenge
Authors:   Institute of industrial Electronics and Electrical Engineering. Riga Technical University  Riga, Latvia, Zakis Janis , Suzdalenko Alexander , Ribickis Leonids , Mineikis Edvins , Repins Alexander , Zverkovicha Yekaterina
Published: August 2022

Race to Zero challenge is a world-wide activity for the universities and colleges to foster the climate goals. This paper analyses the potential of Riga Technical University (RTU) for this action. Different renewable energy sources (PV, wind generators) have been discussed to be installed around the RTU campus. The profiles of electric power consumption are analysed for one faculty and sport centre. The consumption profiles show the amount of power demanded during the working hours, weekends and at night. Energy yield assessment on the roofs is made for two buildings where the configuration of PV panel placement and orientation are analysed that in turn is reflected in the energy generation profile. SCADA system is considered as a monitoring and control tool to visualize power generation and control of the power flow within the system elements.
Fast and Efficient MPC Approaches for Multilevel Drives Considering Cost Function Terms Dependency
Authors:   Electrical Engineering Department, Oregon Institute of Technology. USA, Salem A. , Abido Mohamed A. ,   Electrical Engineering Department King Fahd University for Petroleum and Minerals     Dhahran. Saudi Arabia
Published: August 2022

—Model predictive control (MPC) for multilevel converter has a multi-term cost function that requires high computation burden. In this paper, the deviation terms considered are classified into two categories according to their dependency on the voltage vector or the switching states of the multilevel converter. Subsequently, two approaches to reduce the computation burden are proposed. Mathematical models for the proposed MPC approaches are discussed and analyzed. An experimental platform for a fivelevel T-type multilevel induction drive is used to validate the proposed study. The experimental results show that the proposed approaches have substantially reduced the MPC computation burden compared to the conventional MPC techniques.
Kompetensi Pedagogik Guru dalam Implementasi Pembelajaran Tematik Terpadu di Madrasah Ibtidaiyah
Authors: Ningsih Tutuk , Aziz Mursida
Published: August 2022

Salah satu dari kompetensi guru di abad 21 adalah kompetensi pedagogis. Kompetensi ini menjadi salah satu faktor penting sekaligus penentu keberhasilan guru dalam melakukan kegiatan belajar mengajar. Penelitian ini bertujuan menganalisis kompetensi pedagogis guru dalam pendidikan tematik terpadu di Madrasah Ibtidaiyah Ma’arif 04 Gentasari. Penelitian ini merupakan penelitian lapangan dengan menggunakan pendekatan kualitatif. Pengumpulan data menggunakan tiga teknik yakni observasi lapangan, wawancara secara langsung kepada informan, dan dokumentasi. Setelah data terkumpul, data dianalisis dengan cara mereduksi, menyajikan, dan verifikasi data. Hasil penelitian ini adalah guru telah memenuhi standar kompetensi pedagogik. Hal itu ditunjukkan dengan pemahaman dan analisis yang pendidik peroleh dari siswa. Pemenuhan standar kompetensi pedagogik guru ini menjadi bukti ketercapaian pendidik dalam memberikan kebutuhan siswa. Kompetensi pedagogik yang terpenuhi oleh pendidik berupa melaksanakan pembelajaran, merancang dan melaksanakan evaluasi pembelajaran, menganalisis hasil evaluasi untuk menentukan tingkat ketuntasan belajar (mastery learning); dan memanfaatkan hasilnya untuk memperbaiki kualitas program pembelajaran. Pengembangan yang dilakukan dalam pembelajaran di Madrasah Ibtidaiyah Ma’arif 04 Gentasari memiliki sistem yang baik. Selain itu, ditunjang juga dengan pendidik yang kompeten memberikan pengajaran yang mapan pada siswa.
Strengthening the Micro Teaching Role in the Development of Teacher Candidates Teaching Skills
Authors: Subur Subur
Published: August 2022

This study aims to analyze the micro-teaching course at the Faculty of Tarbiya and Teacher Training (FTIK) IAIN Purwokerto. The laboratories department of FTIK carried out the program. Analyzing its implementation is essential because micro-teaching is a strategic activity to improve teacher competence. Micro teaching is widely associated with efforts to improve teacher skills in education, and thus great attention is required. The data source in this study is the micro-teaching manager and the study program head. It is from observations and interviews. The steps to analyze the data are reduction, data display, verification, and conclusions. The results showed that technical briefing by merging all study programs at the same time, overcrowded participants, unrepresentative speakers for each study program, irrelevant appointed supervisors with the study program, and micro-teaching schedules that coincide with the lectures schedules had the potential to cause the implementation of micro-teaching becomes less effective. It encourages the need to re-enforce the role of micro-teaching to be more effective in providing basic teaching skills for the teacher candidates. The lecture should manage every study program by coordinating with the laboratory. It aims to increase the effectiveness of micro-teaching. The briefing material needs to be supplemented by enrichment various learning strategies relevant to the study program. One lecturer with small classes carries out lectures according to the norms of micro-teaching classes, and the frequency of meetings is adjusted to the regular lecture schedule.
Regular Class vs. Special Class: How Can They Differ in English Achievement and Technology Usage?
Authors: Maula Inayatul , Lina Marisa Fran
Published: August 2022

Providing educational programs provides specific opportunities for better student progress. MTs Negeri 1 Boyolali offers two kinds of programs that can be chosen according to the wishes, abilities, and goals. The two programs are the regular class program and the special class program. These two programs can highlight their technology usage and English learning achievement, considering they come from different programs. Therefore, this study aims to find out whether there are differences in English learning achievement or not between the two programs. This study uses ,a mixed method; statistically collecting and analyzing the students' final semester tests results, and interviewing the teacher and students to clarify some data. Besides, an additional intervies investigates further technology usage during English learning. The data shows differences in English learning achievement and technology usage between students from regular and special class programs. The research is expected to be limited to find the differences between the two classes and to contribute ideas to all related education implementers. Ultimately, regular class students will have English skills that are not much different from students in special classes.
Revista Completa
Authors: Executiva Editoria
Published: August 2022

Revista Completa
Métodos contraceptivos en gatas: pasado, presente y futuro
Authors: Carrasco Sangache Washington Fernando , García Mitacek María Carla , Stornelli María Alejandra
Published: August 2022

El control reproductivo temporal y no quirúrgico en gatas es fundamental para evitar camadas no deseadas y, de esta manera, disminuir la sobrepoblación y sus consecuencias negativas. Con este fin se han estudiado varias drogas, entre las cuales se encuentran progestágenos, andrógenos, melatonina, análogos de la GnRH y vacunas contraceptivas. Algunas de ellas han mostrado efectividad, aunque en determinados casos la duración del efecto contraceptivo no es predecible. Además, no están exentas de producir efectos adversos. En este trabajo se realiza una revisión sobre métodos contraceptivos en gatas, desde el comienzo de su utilización. El mismo reúne información relevante acerca de su utilidad, así como de la complejidad de la contracepción en esta especie, lo cual plantea la necesidad de encontrar alternativas que sean efectivas, seguras y predecibles.
PENGENDALIAN KUALITAS PROSES PRINTING KEMASAN POLYCELLONIUM MENGGUNAKAN METODE SIX SIGMA DI PT. ACP
Authors: Paulin Jennifer , Ahmad Ahmad , Andres Andres
Published: August 2022

PT. ACP merupakan industri yang membuat kemasan khususnya kemasan yang fleksibel. Kemasan ini digunakan untuk melindungi produk seperti makanan, minuman sabun, dan lain- lain. Dalam membuat kemasan, material yang banyak diminati oleh customer adalah material polycellonium. Dalam memproduksi Kemasan menggunakan material pollycelonium terjadi cacat pada proses produksinya, terutama pada proses printing. Proses printing merupakan proses penting yang akan akan mempengaruhi produk akhir sehingga tidak boleh terjadi masalah pada tahap ini, maka tujuan yang ingin dicapai pada penelitian ini adalah mengurangi terjadinya kecacatan pada proses printing dengan menggunakan metode six sigma. Metode Six Sigma terdiri dari tahap DMAIC, yaitu define, measure, analyze, improve dan control. Penelitian ini akan membahas sampai dengan tahap improve. Hasil penelitian menunjukkan nilai DPMO 4471,11. Serta defect yang banyak terjadi adalah miss print, color off, dan ink streaking. Level sigma untuk perusahaan adalah 4 sigma, Cp adalah 0,761 dan Cpk 0,669. Dengan pendekatan FMEA, diketahui bahwa miss print disebabkan oleh kurang telitinya operator, color off di sebabkan oleh kurang skill operator dan ink streaking di sebabkan tinta terkontaminasi. Usulan yang dapat diberikan untuk mengurangi cacat adalah membuat jadwal pelatihan, memperketat pengawasan, dan menghaluskan doctor blade. Kata kunci: Pengendalian kualitas, Six Sigma, DMAIC, FMEA, DPM
Determination of Bisphenol in Indoor Dust Samples by Liquid Chromatography in Combination with Quadrupole Mass Spectrometry (LC-MS/MS)
Authors: Thuy Le Minh , Lieu Dang Thi , Nam Vu Duc , Ngoc Nguyen Thuy , Anh Duong Hong , Tri Tran Manh
Published: August 2022

This study has focused on the development of the method LC-MS/MS to determine 2,2-bis(4-hydroxyphenyl)propane (bisphenol A: BPA) and 4,4’-dihydroxydiphenylmethane (bisphenol F: BPF) in indoor samples by using ultrasonication extraction and solid-phase extraction for preparation. The chromatographic procedure was performed on Kinetex C18 2.1 x 150 mm, 2.6 µm column with mobile phases: 2 mM HCOONH4 in MeOH and H2O:MeOH (90:10,…). The method quantification limits (MQL) of BPA and BPF were 15.0 and 12.0 ng/g, respectively. The mean recoveries were 80.4% for BPA and 93.8% for BPF (RSD<15%). The calibration curve for both BPA and BPF was linear over a concentration range of 1.0 to 500 ng/mL (R2 ≥ 0.999). Twenty-one samples were collected from private houses, laboratories, drug stores, and plastic recycling factories in Hanoi. BPA and BPF were found in dust samples with frequencies of 85.7 and 100%, respectively. Concentrations of BPA and BPF in dust samples were in the ranges of <MQL–2230 ng/g (mean: 626) and <MQL–149,000 ng/g (mean: 14,700), respectively. Based on the measured concentration, the human exposure to bisphenol via indoor dust ingestion was estimated for various age groups. The estimated exposure dose for people working at plastic recycling factories was the highest level (23.6 ng/kg-bw/day) but lower than the oral reference dose by the EPA and the European Food Safety Authority (50 µg/kg-bw/day).
Camilo, una espiritualidad incluyente
Authors: Echeverry Pérez Antonio José , Rivera Zapata Mariana
Published: August 2022

"El siglo XX en Colombia fue el escenario para colectivos revolucionarios, nuevas perspectivas en las ciencias sociales, cambios económicos, y la cuna de individuos dispuestos a liderar procesos de transformaciones nacionales. Una de estas figuras ineludibles, fue Camilo Torres Restrepo, quien, tras más de 50 años de su muerte, sigue siendo un referente de unidad en tiempos de reparación de años de conflicto, fracturas ideológicas, económicas y sociales del país. La biografía del “curita rebelde” ha sido una constante en investigaciones, pero en el presente texto, se pretende reconocer —a través de su experiencia, del conflicto entre fe y vida, entre obra y compromiso, y por supuesto, su gran apuesta por un amor históricamente eficaz— las claves para enfrentar el actual proceso de paz. Recordar, recopilar e investigar perspectivas de la vida de Torres, resulta apremiante, porque invita a hacer un análisis por cada una de sus etapas: primero, de su perfectibilidad (1929-1947) donde se aborda los aspectos de su niñez, familia, escuela, bachillerato e ingreso a la Universidad Nacional; segundo, a su ideal de servicio (1947-1954) cuando Camilo ingresó al Seminario Mayor de Bogotá; tercero, sus pasos por Lovaina (1954-1958) escenario donde realizó sus estudios de sociología, y le dieron más contundencia a su formación espiritual e intelectual; cuarto, al explorar más su perspectiva de cristianismo (1959-1964) y los cambios que ocurrieron al regresar a Colombia; y un quinto y último momento, su proceso de creación del semanario Frente Unido, unión al Ejército de Liberación Nacional y muerte en combate. Todos estos elementos esbozados de la vida de Torres exponen en un discurso de análisis histórico y de exploración en su espiritualidad, que siempre estuvo ligado al diálogo de múltiples voces, abierto a propuestas, dispuesto a construir a partir de lo diverso, nutrido por coetáneos con estos mismos ideales, direccionado a la unidad y al amor eficaz. Claves precisas, para las conversaciones frente a los tiempos de posconflicto en el país."
Functional and stylistic features of C. S. Lewis' sermons
Authors: Sorokina Evgenia Evgen'evna
Published: August 2022

The relevance of the article is due to the relatively small study of the issue of assessing the functional and stylistic features of C. S. Lewis' sermons in modern Russian science. The purpose of this article is to study the preaching addresses of C. S. Lewis from the standpoint of functional stylistics. The object of this work is the sermons of C. S. Lewis, delivered in various churches and at religious meetings, published subsequently as an essay in 1949, the subject is their features from the point of view of functional stylistics, manifested through various techniques. Such methods of work as analytical and descriptive were used in the study. The scientific novelty lies in the consideration of the functional and stylistic features of the texts of C. S. Lewis on the example of sermons, as well as the search for elements of appeal in these works. The conducted research indicates that the sermons of C. S. Lewis are characterized by certain functional and stylistic features expressed by a variety of techniques. Among them are various quotations (from Holy Scripture and fiction), allusions to the above-mentioned works, outdated and high-style forms of words, borrowings, various kinds of analogies and comparisons, as well as various rhetorical techniques (diacopes, hypophores), rhetorical questions, repetitions. In addition, these are various appellative constructions, including various verbs with imperative modality, the so-called "we-constructions", various types of complex conditional sentences. The analysis of these functional and stylistic features allows us to illustrate the position of C. S. Lewis and his understanding of the Christian faith in the context of contemporary life.
Effectiveness of Morphine in Managing Refractory Dyspnoea in Patients with Coronavirus Disease (COVID-19)
Authors: Sirohiya Prashant , Pandey Khushboo , Sagiraju Hari Krishna Raju , Bhatnagar Sushma
Published: August 2022

Opiates are generally used to relieve dyspnoea in advanced diseases such as cancer and lung diseases. However, little is known regarding the safety and efficacy of morphine for refractory dyspnoea in coronavirus disease 2019 (COVID-19) patients. We retrospectively reviewed records of 18 COVID-19-positive patients who were administered morphine for refractory dyspnoea during hospitalisation between May 2021 and June 2021. Details of morphine usage, vital signs, an 11-point dyspnoea numeric rating scale (DNRS) and adverse events at baseline, 24 h and 72 h after the start of treatment were abstracted from records. The final clinical outcome in terms of death or discharge was noted. All patients had severe refractory dyspnoea (DNRS score ≥7) at the time of administration of morphine and had not been relieved from standard care for the past 3 days. In the results, the mean (standard deviation [SD]) age was 47.1 (12) years, male was 13 (72.20%) patients and modified Medical Research Council Grade 4 was present in all 18 patients. The mean (SD) 1st day dose of morphine was 7.03 (1.53) mg and the mean (SD) duration of morphine use was 5.22 (3.00) days. Significant decreases in DNRS, respiratory rate and oxygen saturation were observed 24 h and 72 h after the start of morphine administration. Meanwhile, blood pressure and heart rate were not significantly altered after treatment. The finding of this single-centre retrospective study indicates that morphine may be considered for use in the management of refractory dyspnoea among COVID-19 patients.
IoT Based Monitoring and Control System of Siam Banjar Orange Plants using Fuzzy Logic Control
Authors: Alkaff Muhammad , Fajar Zulkarnain Andry , Iqbal Rizqi Muhammad
Published: August 2022

South Kalimantan is one of the largest citrus fruit producers in Indonesia. One of the leading citrus fruit commodities in South Kalimantan is the Siam Banjar oranges (Citrus reticulata). This study developed a monitoring and control system for Siam Banjar orange plants based on IoT (Internet of Things) and Fuzzy Logic Control. The goal is to determine the performance of the Fuzzy Logic Control method in predicting the time to water plants based on temperature and soil moisture. The prototype comprises a Wemos D1 R1 microcontroller with DHT22 and an FC-28 moisture sensor. Two input parameters, temperature and soil moisture are utilised in Fuzzy Logic Control calculations. The output is the duration of the watering time in seconds. During testing, the value of the sensor is compared to existing manual instruments. In addition, fuzzy MatLab calculations are compared to the Fuzzy Logic Control method calculations. The FC-28 Soil Moisture sensor and hygrometer had an error rate of 3.2%, while the DHT22 sensor and thermometer had 1%. The Fuzzy Logic Control test for watering using fuzzy calculations in MatLab yielded a 3 per cent error rate.
Treatment of Kynol fiber materials – Part 2: antistatic and water-repellent functionalization
Authors: Wang Juan , Mahltig Boris
Published: August 2022

Kynol fibers are flame retardant high performance fibers. Without further treatment they do not exhibit significant antistatic or water-repellent properties. With this background, several conventional antistatic agents and one hydrophobic finishing agent are evaluated to introduce these properties to Kynol fiber materials. Also, the combination of both properties is investigated to realize bifunctional fiber materials. By application of antistatic finishing agents, the electric surface resistance of Kynol fiber materials can be decreased to values smaller 108 W, which is a good value related to antistatic properties. By application of the hydrophobic agent, water repellent properties can be introduced to Kynol fiber materials. However, simultaneously the antistatic properties are decreased. The combination of both types of agents in a kind of bifunctional finishing can lead to intermediate antistatic effects combined with an intermediate water repellency. Nevertheless, in bifunctional application no single excellent property is gained. The flame retardant properties are tested on selected samples after the finishing processes. No change in flame retardant properties is determined, if the finishing agents are applied. For this, the presented results can be the starting point for development of functionalized flame retardant Kynol fiber products.
From LUVs to GUVs - how to cover micrometer-sized pores with membranes
Authors: Kramer Kristina , Sari Merve , Schulze Kathrin , Flegel Hendrik , Stehr Miriam , Mey Ingo , Janshoff Andreas , Steinem Claudia
Published: August 2022

Pore-spanning membranes (PSMs) are a versatile tool to investigate membrane-conﬁned processes in a bottom-up approach. Pore sizes in the micrometer range are most suited to visualize PSMs using ﬂuorescence microscopy. However, the preparation of these PSMs relies on the spreading of giant unilamellar vesicles (GUVs). GUV production faces several limitations. Thus, alternative ways to generate PSMs starting from large or small unilamellar vesicles that are more reproducibly prepared, are highly desirable. Here we describe a method to produce PSMs obtained from large unilamellar vesicles making use of droplet-stabilized GUVs generated in a microﬂuidic device. We analyzed the lipid diﬀusion in the free-standing and supported parts of the PSMs using z-scan ﬂuorescence correlation spectroscopy and ﬂuorescence recovery after photobleaching experiments in combination with ﬁnite element simulations. Employing atomic force indentation experiments, we also investigated the mechanical properties of the PSMs. Both, lipid diﬀusion constants and lateral membrane tension were compared to those obtained on PSMs derived from electroformed GUVs, which are known to be solvent- and detergent-free, under otherwise identical conditions. Our results demonstrate that the lipid diﬀusion, as well as the mechanical properties of the resulting PSMs, are almost unaﬀected by the GUV formation procedure but depend on the chosen substrate. With the new method in hand, we were then able to reconstitute the syntaxin-1A transmembrane domain in microﬂuidic GUVs and PSMs, which was visualized by ﬂuorescence microscopy.
Remote Formation of Arynes via Formal Dehydrogenation of Arenes
Authors: Roberts Riley , Metze Bryan , Nilova Aleksandra , Stuart David
Published: August 2022

Arynes offer immense potential for diversification of benezenoid cores, which occur in pharmaceuticals, agrochemicals, and liquid crystals. However, accessing these high-energy intermediates requires either harsh conditions or multi-step syntheses of designer reagents, and alternative methods with simpler substrates and milder conditions remain under- developed. Here, we describe a two-step formal dehydrogenation of simple arenes to generate arynes at a remote position relative to traditionally reactive groups, i.e., halides. This approach is enabled by regioselective installation and ejection of an “onium” leaving group, and we demonstrate the compatibility of simple arenes (20 examples) and arynophiles (6 examples). The mildness of this strategy is highlighted by formal dehydrogenation of clofibrate, an active pharmaceutical ingredient, and demonstrates that arynes are viable intermediates for late-stage functionalization. Finally, we show that aryne intermediates offer opportunities for orthogonal C-H amination relative to other methods.
CX-ASAP: A high throughput tool for the serial refinement and analysis of crystallographic data collected under varying conditions
Authors: Thompson Amy , Smith Kate , Clegg Jack , Price Jason
Published: August 2022

Abstract CX-ASAP is a new open-source software project designed to greatly reduce the time required analysing crystallographic data collected under varying conditions. Scripted in Python3, CX-ASAP can automatically refine, finalise and analyse data collections with wide-ranging temperatures/pressures etc. This is done by use of a reference structure, allowing for quick identification of problems, phase changes and even model comparison. The modular design means that new features and custom scripts can be easily added, tailoring the capabilities to the specific needs of the user. It is envisioned that CX-ASAP will help close the growing gap between fast collection times and slow data finalisation.
Fragments quantum descriptors in classification of bio-accumulative compounds
Authors: Fliszkiewicz Bartłomiej , Sajdak Marcin
Published: August 2022

The aim of the following research is to assess the applicability of calculated quantum properties of molecular fragments as molecular descriptors in machine learning classification task. The research is based on bio-concentration and QM9-extended databases. A number of compounds with results from quantum-chemical calculations conducted with Psi4 quantum chemistry package was also added to the quantum properties database. Classification results are compared with a baseline of random guesses and predictions obtained with the traditional RDKit generated molecular descriptors. Chosen classification metrics show that fragments quantum descriptors are capable of yielding more accurate predictions than the baseline and comparable with those provided by molecular descriptors widely applied in cheminformatics.
Large interactive touchscreens as an opportunity for hybrid teaching during COVID-19 pandemic and beyond
Authors: Danjou Pierre-Edouard , Bouhsina Saâd , Billet Sylvain , Cazier-Dennin Francine
Published: August 2022

The year 2020 will be remembered as the year of COVID-19 and its subsequent lockdowns. This pandemic has profoundly changed the way we teach by forcing many institutions to offer their courses online. The time to come back to face-to-face teaching has arrived, but the shadow of the disease still hangs over teachers, students and society more generally. Disruption in teaching can still occur for students, or even teachers, if they are either diagnosed COVID-19 positive or contact case and forced to self-isolate. In order to limit the impact of self-isolation on learning, hybrid teaching (i.e. teaching face-to-face to students in a classroom and to online students at the same time) was successfully implemented owing to the combination of a videoconference software and a large interactive touchscreen. The set-up presented in this paper allows to broadcast courses to at-home students (i.e. voice, visual pedagogic support and, more interestingly, indications handwritten by the teacher) while simultaneously teaching face-to-face to students in the classroom. It also allows to self-isolated teacher to teach tutorial from home to students in the classroom. This paper focuses on the use of large interactive touchscreens for hybrid teaching. In order to evaluate this pedagogical approach, a questionnaire was completed by students and results discussed.
Common Structural Features of Hydrophobic α-Helical Hot Spots: Insights for the Design of Novel α-Helix Mimetics
Authors: Kell Shelby R. , Wang Zhen , Ji Haitao
Published: August 2022

The binding conformations of hydrophobic α-helical hot spots are convergent into two spatial areas in protein–protein interaction (PPI) complex structures. The physical basis for convergence was disclosed, which enables the generation of pharmacophore models for i/i + 4/i + 7 or i/i + 3/i + 4 α-helical hot spots. Further investigation revealed that this convergence of binding conformations is common among all hydrophobic α-helical hot spots regardless of helical positions. This observation led to a streamlined generation of pharmacophore models for hydrophobic hot spots at any positions along the α-helix. These successfully evaluated pharmacophore models may be useful for designing novel α-helical hot spot mimetics for regulations of α-helix-mediated PPIs.
Hastane İçme ve Kullanma Sularının Mikrobiyolojik Analizi; Sakarya
Authors: ÇAVDAR Gökhan , KÖROĞLU Mehmet , ÖLMEZ Mehmet , ÖZÖZEN ŞAHİN Elif , ALTINDİŞ Mustafa
Published: August 2022

Amaç: Bu çalışmada hastane içme, kullanma suyu ve sürüntü örnekleri mikrobiyolojik yönden incelenerek, risk oluşturup oluşturmadığı araştırıldı.Materyal ve Metot: Araştırmamızda 40 farklı içme ve kullanma suyu başlıklarından alınan su ve sürüntü örnekleri ayrı ayrı olarak farklı yöntemlerle incelendi. Su örneklerinin mikrobiyolojik analizleri için membran filtrasyon yöntemi ve sürüntü örnekleri için tek koloni düşürme ekim yöntemi kullanıldı. Ayrıca çalışmada kullanılan besiyerlerinde üreyen mikroorganizmalar MALDI-TOF MS ile identifiye edildi.Bulgular: Alınan su ve sürüntü örneklerinin kültürü neticesinde; E. coli, diğer koliform grubu bakteriler, Enterokok ve Legionella spp. üremesi saptanmadı. Bunun dışındaki mikroorganizmaların sürüntü örneklerindeki üreme oranları; %22,5 Staphylococcus spp., %5 Bacillus spp., %10 M. luteus, %10 Küf ve maya ve %2,5 P. oryzihabitans’tır. İncelenen su örneklerindeki mikroorganizmaların üreme oranları sırasıyla; %15 Staphylococcus spp., %15 Bacillus spp. ve %5 Acinetobacter spp. şeklindedir.Sonuç: Hastanelerde içme ve kullanma suyu sürüntü örneklerinde fırsatçı patojen bakterilerin izole edilmesi özellikle immünitesi zayıf hastalarda risk oluşturması açısından önemlidir. Bu çalışmada hastanemiz içme ve kullanma sularının Koliform grubu bakteriler, E. coli, Enterokok ve Legionella spp bakterileri açısından risk oluşturmadığı görülmüştür. Fakat hastanemizde yaptığımız analizde fırsatçı patojen bakterilerin izole edilmesi önem arz etmektedir. Bu fırsatçı patojenlerin özellikle immündüşkün hastalarda sağlık sorunlarına neden olabileceği göz ardı edilmemelidir.ndüşkün hastalarda önemli sağlık sorunlarına neden olabileceği göz ardı edilmemelidir.
Çocuk Hastalarda Düşme Riski ve Hemşirelerin Görüşlerinin Belirlenmesi
Authors: ATALAY ÖZKILIÇ Devran , KARDAŞ ÖZDEMİR Funda
Published: August 2022

Amaç: Bu araştırma, çocuk hastalarda düşme riskini değerlendirmek ve hemşirelerin bu konudaki görüşlerini belirlemek amacıyla yapılmıştır.Materyal ve Metot: Tanımlayıcı ve kesitsel türdeki araştırmanın evrenini, Kars ilinde bulunan hastanelerin kliniklerinde yatarak tedavi görmekte olan 0-18 yaş arası çocuklar (N:161) ve bu kliniklerde çalışan hemşireler (N: 60) oluşturmuştur. Veriler; “Çocuk Düşme Riski Değerlendirme Formu”, Hemşireler İçin Tanıtıcı Bilgi Formu” ve “BUÇH II Düşme Riski Tanılama Ölçeği” ile toplanmıştır. Araştırma verileri SPSS for Windows 20 programı ile analiz edilmiştir.Bulgular: Çocukların %41,6’sında BUÇH II skoruna göre düşme riski vardır ve ortalama düşme riski puanı 5,06±1,04’dür. Erkek çocukların, 1-6 yaş grubunda olanların, oryantasyon sorunu olmayanların, ebeveyni yanında olanların, sedasyon almayanların ve mobilizasyonda kısıtlaması olmayanların düşme riski taşıma oranları daha yüksektir. Hemşirelerin %58,3’ü çocuklardaki düşmeleri mesleki bir hata olarak görmemektedir bununla birlikte %90’ı hemşirenin çocuklardaki düşmelerin önlenmesi ile ilgili sorumluluğu olduğunu düşünmektedir. Hemşirelerin %96,7’si her çocuğun düşme riski yönünden değerlendirilmesi gerektiğini, %85’i çalıştığı klinikte her çocuğu düşme riski açısından değerlendirdiğini ve %78,3’ü çalıştığı klinikte düşmeye yönelik yeterince önlem alındığını bildirmiştir.Sonuç: Çocuk hastaların önemli bir bölümü düşme açısından risklidir. Hastanede yatan tüm çocukların düşme risk düzeyleri uygun değerlendirme araçları kullanılarak belirlenebilir ve hemşirelerin düşmeyi önleme programları kapsamında yapılacak eğitimlerle konu hakkındaki farkındalıkları artırılabilir.
Prognostic Value and Significance of Oxidative Stress in Breast Cancer
Authors: ZENGİN İsmail , KOÇER Havva Belma , DEMİRAY Tayfur , YILMAZ Kerem
Published: August 2022

Objective: The aims of this study were to investigate Total Antioxidative Status (TAS), Total Oxidative Status (TOS), and Oxidative Stress Index (OSI) levels in breast cancer patients and compare them to levels in healthy women.Materials and Methods: In the study, 45 breast cancer patients and 46 healthy women participated. The OSI value was calculated as the % ratio of the TAS and TOS values. The data were analyzed on IBM SPSS 21.0 package software.Results: When the mean TOS values in patients and healthy women were compared, the control group had a TOS of 3.44 µ mIU/L and the patient group had a TOS of 11.93 µ mIU/L. TAS was found to have a mean value of 1.74 µ mIU/L in the control group and 1.63 m/mol/L in the patient group. OSI was determined to have a mean value of 7.23 in patients with breast cancer and 1.99 in healthy women. In female patients with breast cancer, TOS value was higher, TAS value was lower, and OSI value was significantly higher than healthy women (p<0.01).Conclusion: TOS, TAS and OSI values ​​can be a marker that can be used to differentiate patients with breast cancer and healthy women.
The Attitudes of the Patients with the Multisystem Inflammatory Syndrome in Children Secondary to SARS-CoV-2 Regarding COVID-19 Vaccines
Authors: AKGÜN Eviç Zeynep , AYDIN Dicle , SÖNMEZ Hafize Emine , BABAOĞLU Kadir
Published: August 2022

Objective: Multisystem inflammatory syndrome (MIS-C) in children is an abnormal immune response that occurs after exposure to SARS-CoV-2. To our knowledge, there is no study demonstrating the efficacy and safety of the BNT162b2 mRNA vaccine in children who were diagnosed with MIS-C previously. In this study, we aimed to present the attitudes of MIS-C patients over the age of 12 years towards the COVID-19 vaccine, and the side effects of the vaccine in vaccinated patients.Materials and Methods: The files of patients who were followed up with the diagnosis of MIS-C between May 2020 and January 2022 aged 12 years and over were reviewed retrospectively.Results: Thirty-six patients (12 girls, 24 boys) were included in the study. The median age was 13.5 (12-17) years. Eight of the 36 patients (22.2%) were vaccinated at a median of 3 (3-6) months after the diagnosis of MIS-C. No side effects or disease reactivation was observed following vaccination. The most common reasons for patients' refusal to be vaccinated were having had the disease and being concerned about a recurrence.Conclusion: This study showed that COVID-19 vaccination was safe in children who were diagnosed with MIS-C, although most of our patients were against it.
The Relationship between Cloninger’s Temperament and Character Dimensions, and Depression Treatment Outcome
Authors: GÜRÜ Meltem , CENGİZ Gül Ferda , ÖRSEL Sibel
Published: August 2022

Objective: The aim of our study is to investigate the relationship between Temperament and Character Inventory (TCI) dimensions and treatment response in Major Depressive Disorder (MDD) patients.Materials and Methods: 88 patients diagnosed with MDD were included in the study. Patients were given Sociodemographic Data Form, Beck Depression Inventory (BDI) and TCI before the treatment. According to the BDI, which was applied 8 weeks after the treatment, the patients were divided into two groups as those who responded to the treatment and those who did not (responders and non-responders).Results: The education level of the patients was statistically higher in the responders. The number of unemployed (92.3%) patients in the non-responders was statistically higher than the number of unemployed (41.3%) patients in the responders. The number of patients with severe depression was statistically significantly higher in the non-responders. The mean harm avoidence score of the patients in the non-responders were found to be statistically higher than in the responders. The mean persistence score of the patients in the responders was found to be statistically higher than the non-responders.Conclusion: Our study shows that some sociodemographic characteristics and TCI dimensions may be associated with early treatment response in MDD patients.
MACHINE LEARNING TO PREDICT STUDENT ACADEMIC RISK IN ENGINEERING
Authors: Roldán Jiménez Lizeth Stephany
Published: August 2022

Identifying academic risk in an engineering program is very important since it allows to stablish policies that can be applied to prevent it and to guarantee student success. At Pontificia Universidad Javeriana in Bogotá – Colombia, we have developed some methods that can be used to predict the number of students that are in academic risk or even in dropout risk. This information can be employed to identify possible actions and interventions in our programs. We focus in the necessity to design and implement models to recognize patterns associated with academic performance and transitions of undergraduate students.Our strategies are faced to accompany the students. Once we identify the risk, every student is evaluated by an academic adviser, who is in charge of determining the possible causes of the low performance and this way customize the support. In this sense, weaknesses are identified around CDIO competencies, for example, interpersonal competences, basic knowledge, algorithmic thinking, problem solving or personal skills. In this way, students are routed to different strategies to strengthen those abilities.This paper starts with an introduction justifying this work. After that, a section describes the methodology to predict academic risk. Then, we present our accompaniment strategies. Some future works are also presented. In this context, this work tries to give hints about particular intervention for student in risk.
TÉCNICA PROCESSOR IN THE LOOP (PIL) APLICADA EN EL DESARROLLO DE PRÁCTICAS DE LABORATORIO DE INGENIERÍA ELECTRÓNICA
Authors: Guerrero Guerrero Andrés Felipe , Delgado Torres Lucero de Fátima , Escobar Ortíz Edwin Sneider
Published: August 2022

En este artículo se propone una metodología para desarrollo de prácticas de laboratorio en ingeniería electrónica tomando como base teórica el modelo experiencial de Kolb y la técnica de implementación Processor in the Loop (PIL). Esta metodología se presenta como una alternativa para solventar las necesidades evidentes de desarrollo experimental en ambientes virtuales y remotos de aprendizaje. La metodología ha sido aplicada en el núcleo temático denominado Control Discreto en el programa de Ingeniería Electrónica de la Universidad de Cundinamarca. Los resultados muestran alto grado de aceptación en la población estudiantil.
ESTRATEGIA PARA LA ENSEÑANZA DE CINEMÁTICA EN INGENIERÍA BASADA EN LABORATORIOS REMOTOS INTERINSTITUCIONALES
Authors: Trujillo Suárez Carlos , Restrepo Martínez Alejandro , César Correa Julio
Published: August 2022

La estrategia de los autores para desarrollar prácticas remotas, denominados en este trabajo laboratorios remotos, para los cursos afines al análisis dinámico de máquinas y mecanismos dictados en las instituciones aliadas, pretende aprovechar y compartir los recursos disponibles en cada una de ellas. En los actuales momentos, este tipo de estrategia se plantea como una opción para enfrentar los retos impuestos por la pandemia de Covid-19, pero es igualmente válida cuando se puedan retomar plenamente las actividades presenciales. La experiencia colaborativa presentada en este trabajo se enmarca en la cinemática, la cual es una de las etapas iniciales del análisis y diseño de sistemas mecánicos relevantes para ingeniería. Además de reforzar la colaboración interinstitucional, la estrategia apunta a atender la dificultad en los estudiantes para hacer mediciones e interpretar la influencia de variables cinemáticas.
Magel2knockdown in hypothalamic POMC neurons innervating the medial amygdala reduces susceptibility to diet-induced obesity
Authors: Choi Yuna , Min Hyeon-Young , Hwang Jiyeon , Jo Young-Hwan
Published: August 2022

Hyperphagia and obesity profoundly affect the health of children with Prader–Willi syndrome (PWS). TheMagel2gene among the genes in the Prader–Willi syndrome deletion region is expressed in proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC). Knockout of theMagel2gene disrupts POMC neuronal circuits and functions. Here, we report that loss of theMagel2gene exclusively in ARCPOMCneurons innervating the medial amygdala (MeA) causes a reduction in body weight in both male and female mice fed with a high-fat diet. This anti-obesity effect is associated with an increased locomotor activity. There are no significant differences in glucose and insulin tolerance in mice without theMagel2gene in ARCPOMCneurons innervating the MeA. Plasma estrogen levels are higher in female mutant mice than in controls. Blockade of the G protein–coupled estrogen receptor (GPER), but not estrogen receptor-α (ER-α), reduces locomotor activity in female mutant mice. Hence, our study provides evidence that knockdown of theMagel2gene in ARCPOMCneurons innervating the MeA reduces susceptibility to diet-induced obesity with increased locomotor activity through activation of central GPER.
The L-NAME mouse model of preeclampsia and impact to long-term maternal cardiovascular health
Authors: de Alwis Natasha , Binder Natalie K , Beard Sally , Mangwiro Yeukai TM , Kadife Elif , Cuffe James SM , Keenan Emerson , Fato Bianca R , Kaitu’u-Lino Tu’uhevaha J , Brownfoot Fiona C , Marshall Sarah A , Hannan Natalie J
Published: August 2022

Preeclampsia affects ∼2–8% of pregnancies worldwide. It is associated with increased long-term maternal cardiovascular disease risk. This study assesses the effect of the vasoconstrictor N(ω)-nitro-L-arginine methyl ester (L-NAME) in modelling preeclampsia in mice, and its long-term effects on maternal cardiovascular health. In this study, we found that L-NAME administration mimicked key characteristics of preeclampsia, including elevated blood pressure, impaired fetal and placental growth, and increased circulating endothelin-1 (vasoconstrictor), soluble fms-like tyrosine kinase-1 (anti-angiogenic factor), and C-reactive protein (inflammatory marker). Post-delivery, mice that received L-NAME in pregnancy recovered, with no discernible changes in measured cardiovascular indices at 1-, 2-, and 4-wk post-delivery, compared with matched controls. At 10-wk post-delivery, arteries collected from the L-NAME mice constricted significantly more to phenylephrine than controls. In addition, these mice had increased kidneyMmp9:Timp1and heartTnfmRNA expression, indicating increased inflammation. These findings suggest that though administration of L-NAME in mice certainly models key characteristics of preeclampsia during pregnancy, it does not appear to model the adverse increase in cardiovascular disease risk seen in individuals after preeclampsia.
Relação entre dois testes funcionais: Teste de levantar-se e se sentar da cadeira de 30s e timed up and go
Authors: Zazá Daniela , Chagas Mauro , Menzel Hans-Joachim , Campos Jaqueline , Campos Carlos
Published: August 2022

Os testes funcionais de levantar-se e se sentar da cadeira de 30s (TLS30s) e o teste Timed Up and Go (TUG) são utilizados com objetivo de fornecer informações sobre o desempenho da força muscular de membros inferiores e a agilidade funcional em idosos, respectivamente. Embora ambos os testes tenham como objetivo avaliar diferentes aspectos da aptidão funcional, o nível de variância comum entre esses testes ainda não foi determinado. Assim, o presente estudo tem como objetivo verificar o nível de correlação entre os desempenhos nos testes TUG e o TLS30s e comparar os resultados com valores de referência para indivíduos idosos ativos, independentes e do sexo feminino. Participaram voluntariamente deste estudo 47 mulheres idosas saudáveis, que realizavam atividade física (hidroginástica) há pelo menos seis meses, duas vezes por semana e com duração de 60 minutos cada sessão. As idosas foram submetidas primeiramente ao teste TLS30s e na sequência ao TUG. O coeficiente de correlação de Pearson foi calculado entre o número máximo de repetições realizadas no TLS30s e o tempo gasto para executar o teste TUG. Foi verificada uma correlação significativa, porém baixa (r = -.563; p < .05) entre os dados obtidos nos testes. Baseado na baixa variância comum (31.7%) foi possível concluir que os testes realizados apresentam exigências distintas para o sistema neuromuscular. O desempenho do grupo amostra foi superior para o TLS30s comparado com os valores de referência, enquanto para o TUG o desempenho foi similar aos valores de referência.
Assessing the determinants of unhealthy dietary habits among a sample of survey participants in Jamaica
Authors: La Foucade Althea , Gabriel Samuel , Beharry Vyjanti , Laptiste Christine , Metivier Charmaine , Samuels T. Alafia , Theodore Karl , Edwards-Wescott Patricia
Published: August 2022

Objective.

To identify and assess the determinants of unhealthy dietary habits among a sample of survey participants in Jamaica.

Methods.

Because of resource constraints, this cross-sectional assessment is based on a three-stage non-probability sample of 374 survey respondents in Jamaica aged ≥18 years. Firstly, three administrative areas (parishes) were randomly selected. Secondly, the main commercial areas within the selected parishes were identified, from which a non-probability sample of establishments was drawn. A broad selection of establishments covering public, private, and nongovernmental organizations was chosen. This array of establishments was selected to capture a sample of respondents that was as representative as possible. Patrons and employees in the selected establishments were asked to complete a questionnaire.

Results.

Respondents’ self-assessment of their general consumption revealed that 48.4% were unhealthy eaters. Among these, the top reasons for generally unhealthy dietary choices were greater accessibility of unhealthy foods (63.5%) and limited time to prepare healthy meals (61.3%). Additionally, 52.5% indicated “unhealthy foods cost less,” and 47.0% identified affordability as the main factor in the food choice equation. Findings revealed that the determinants of eating unhealthily tended to vary across income, age, and gender. Female, younger, and lower-income respondents have a higher likelihood of being impacted by the factors.

Conclusions.

The largest proportions of the sample identified limited time to prepare healthy meals and the ease of access to unhealthy foods as the foremost determinants of unhealthy eating habits. These barriers to healthy eating are more likely to impact survey participants in the 18–34 age group.
Escritoras gaúchas: um estudo do periódico Corymbo (1885-1925)
Authors: Vieira Miriam Steffen
Published: August 2022

Este texto apresenta o periódico Corymbo, editado por Revocata Heloísa de Mello e Julieta de Mello Monteiro, na cidade de Rio Grande (RS), no período de 1883 a 1943, como um empreendimento literário feminino, com vistas à inserção e ao reconhecimento de mulheres escritoras. Para tanto, examina-se o período de 1885 a 1925, destacando duas dimensões. Uma primeira, sobre a forma como está organizado (formato, circulação e questões financeiras), e uma segunda, sobre os conteúdos desenvolvidos, como instrução, relação com maçonaria e luta pelo reconhecimento intelectual das mulheres. Dessa perspectiva, visa a contribuir com a história da imprensa literária desenvolvida por mulheres no sul do país.
Suplementos literários ou cadernos de cultura? Um panorama histórico do Jornalismo Cultural
Authors: Bortoluzzi Rigo Larissa , Hohlfeldt Antonio
Published: August 2022

Partindo do entendimento de Jornalismo Cultural (LIMA, 2013; FARO, 2006), a reflexão se dá sobre as configurações desse campo, por meio de suplemento e caderno de cultura, para traçar um panorama histórico e social. Utiliza-se como metodologia a análise sócio-histórica, com pesquisa bibliográfica (STUMPF, 2005; FONSECA, 2008). Ressaltam-se exemplos como O Estado de S. Paulo e Jornal do Brasil, pioneiros desse tipo de publicação, juntamente com veículos mais regionais, “Suplemento Literário Minas Gerais” (SMLG) e “Caderno de Sábado” (CS). Já os contemporâneos Rascunho e Peixe Elétrico ilustram as alterações à escola industrial e se adaptam às novas tecnologias. A análise evidenciou que mesmo com as mudanças de suporte e modernização, os suplementos/cadernos de cultura sofreram modificações para além daquelas de ordem tecnológica.