bluuebunny/crossref_metadata_2025 huggingface dataset:
Impaired microRNA processing in neutrophils from rheumatoid arthritis patients confers their pathogenic profile. Modulation by biological therapies
Authors: De la Rosa Ivan Arias , Perez-Sanchez Carlos , Ruiz-Limon Patricia , Patiño-Trives Alejandra , Torres-Granados Carmen , Jimenez-Gomez Yolanda , Del Carmen Abalos-Aguilera Maria , Cecchi Irene , Ortega Rafaela , Caracuel Miguel Angel , Calvo-Gutierrez Jerusalem , Escudero-Contreras Alejandro , Collantes-Estevez Eduardo , Lopez-Pedrera Chary , Barbarroja Nuria
Published: January 2020

The aim of this study was to investigate the microRNA (miRNA) expression pattern in neutrophils from rheumatoid arthritis (RA) patients and its contribution to their pathogenic profile and to analyze the effect of specific autoantibodies or inflammatory components in the regulation of miRNA in RA neutrophils and its modulation by biological therapies. Neutrophils were isolated from paired peripheral blood (PB) and synovial fluid samples of 40 patients with RA and from PB of 40 healthy donors. A miRNA array was performed using nCounter technology. Neutrophils from healthy donors were treated in vitrowith antibodies to citrullinated protein antigens isolated from RA patients and tumor necrosis factor-a (TNF-a) or interleukin-6. A number of cytokines and chemokines were analyzed. In vitro treatments of RA-neutrophils with tocilizumab or infliximab were carried out. Transfections with pre-miRNA and DICER downregulation experiments were further performed. RA-neutrophils showed a global downregulation of miRNA and genes involved in their biogenesis, alongside with an upregulation of various potential mRNA targets related to migration and inflammation. Decreased levels of miRNA and DICER correlated with autoimmunity, inflammation and disease activity. Citrullinated protein antigens and TNF-a decreased the expression of numerous miRNA and their biogenesis-related genes, increasing their potential mRNA targets. Infliximab reversed those effects. Transfections with pre-miRNA-223, -126 and -148a specifically modulated genes regulating inflammation, survival and migration whereas DICER depletion influenced the inflammatory profile of neutrophils. Taken together RA-neutrophils exhibited a global low abundance of miRNA induced by autoantibodies and inflammatory markers, which potentially contributed to their pathogenic activation. miRNA biogenesis was significantly impaired in RAneutrophils and further associated with a greater downregulation of miRNA mainly related to migration and inflammation in synovial fluid neutrophils. Finally, anti-TNF-a and anti-interleukin-6 receptor treatments can modulate miRNA levels in the neutrophils, minimizing their inflammatory profile.
Autologous stem cell transplantation for progressive systemic sclerosis: a prospective non-interventional study from the European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party
Authors: Joerg Henes  , Maria Carolina Oliveira  , Myriam Labopin  , Manuela Badoglio  , Hans Ulrich Scherer  , Nicoletta Del Papa  , Thomas Daikeler  , Marc Schmalzing  , Roland Schroers  , Thierry Martin  , Gregory Pugnet  , Belinda Simoes  , David Michonneau  , Erik W.A. Marijt  , Bruno Lioure  , Jacques Olivier Bay  , John A. Snowden  , Montserrat Rovira  , Anne Huynh  , Francesco Onida  , Lothar Kanz  , Zora Marjanovic  , Dominique Farge
Published: January 2020

Three randomized controlled trials in early severe systemic sclerosis demonstrated that autologous hematopoietic stem cell transplantation was superior to standard cyclophosphamide therapy. This European Society for Blood and Marrow Transplantation multi-center prospective non-interventional study was designed to further decipher efficacy and safety of this procedure for severe systemic sclerosis patients in real-life practice and to search for prognostic factors. All consecutive adult systemic sclerosis patients undergoing a first autologous hematopoietic stem cell transplantation between December 2012 and February 2016 were prospectively included in the study. Primary endpoint was progression free survival. Secondary endpoints were overall survival, non-relapse mortality, response and incidence of progression. Eighty systemic sclerosis patients were included. Median follow-up duration was 24 (6-57) months after stem cell transplantation using cyclophosphamide plus antithymocyte globulins conditioning for all, with CD34+ selection in 35 patients. At 2 years, progression free survival was 81.8%, overall survival was 90%, response was 88.7% and incidence of progression was 11.9%. The 100 days non-relapse mortality was 6.25% (n=5) with four deaths from cardiac event, including three due to cyclophosphamide toxicity. Modified Rodnan skin score and forced vital capacity improved with time (p< 0.001). By multivariate analysis, baseline skin score >24 and older age at transplant were associated with lower progression free survival (Hazard ration 3.32) and 1.77, respectively). CD34+-selection was associated with better response (Hazard ration: 0.46). This study confirms the efficacy of autologous stem cell transplantation in real-life practice for severe systemic sclerosis using non myeloablative conditioning. Careful cardio-pulmonary assessment to identify organ involvement at patient referral, reduced cyclophosphamide doses and CD34+ selection may improve outcomes. The study was registered at ClinicalTrials.gov: NCT02516124
Endoscopic Transcortical Transventricular Colloid Cyst Excision — Our Experience
Authors: Haroon Kaisar , Taher Tania , Alamgir Abdullah , Reza Arif , Hossain Sk Sader
Published: January 2020

Background: Colloid cyst of the third ventricle is a tumour arising from the roof of the third ventricle at the foramen of Monro. Endoscopic excision of colloid cyst is well established technique. There is less morbidity in comparison to the microsurgical resection.
Materials and method: Seven patients with colloid cyst were treated with endoscopic excision. Of these five were males and two were female patients. Age ranged thirty to fifty five years from a period from Jan 2016 to Mar 2019 in NINS&H.
Results: Most patients had signs of raised intracranial pressure before surgery. Six patients needed post operative VP shunt. Some patients had contusion of the fornix but did not have any memory impairment. Five patients had remnant but there was no symptoms after surgery.
Conclusion: Endoscopic excision of the colloid cyst is a good option. Total removal of the tumour is the goal but little remnant of the tumour attached to the tela choroidae is accepted. One year follow-up showed no recurrence of the cyst.
Bang. J Neurosurgery 2020; 9(2): 94-98
Prevalence and Risk Factors of Low Back Pain among Medical Professionals Working In Selected Tertiary Hospitals in Dhaka City
Authors: Islam Md Joynul , Haseen Fariha , Saha Sanat Kumar , Khasru Moshiur Rahman , Morshed Mahboob , Salek AKM
Published: January 2020

Background: Health care workers are most frequently suffering from lower back pain.
Objective: The purpose of the present study was to determine the prevalence and the effects of low back pain among health care providers working in Dhaka city.
Methodology: This descriptivecross sectional study was conducted in Department of Neurosurgery at National Institute of Neurosciences & Hospital, Dhaka, Bangladesh from July 2012 to June 2013 for a period of one (1) year. The physicians and nurses who were working in the public hospital at any age group of both male and female were selected as study population. The details of the history of the physicians and nurses regarding their life style, hour of practising, and the mode of work and so on were asked in face to faced interview. A survey was carried out to174 conveniently selected participants to be filled and completed. Both descriptive and inferential tests were reported.
Result:A total number of 117 medical professional were recruited from 5 hospital in Dhaka city. Majority medical professionals were from BSMMU (48.0%).The majority study subjects were mentioned that they had spent 6 to 12 hours every day for work which was 92(53.8%). Most of the respondents mentioned that the working environment was very good to fair. The prevalence of low back pain was found in almost every respondents which was 113(66.1) subjects. Interestingly most of the respondents were clearly stated that the LBP was occurred after joining in the work. In this study majority of the respondents were given the history of localized low back pain which was 86(76.1%) subjects. Moderate intensity of pain was reported by most of the respondents which was 67(59.3%) subjects. Intermittent nature of pain was mostly recorded which was 70(61.9%) subjects.There were several individual and profession risks factors were retrieved from the respondents. Many study subjects were given the answer about lifting objects or patients from bed to bed or wheel chair which was 55(48.7%) subjects. About 91(80.5%) respondents had said that pain was due to bad body posture.
Conclusion: In conclusion most of the medical professionals are suffering from moderate intensity lower back pain after joining of their job
Bang. J Neurosurgery 2020; 9(2): 135-141
RISKS OF SOCIAL EXCLUSION IN THE INTERACTION OF THE STATE AND THE FAMILY IN THE ELDERLY CARE SYSTEM
Authors: Patyan L. , Golubeva E. Yu. , Szeman Z. , Robert M. A.
Published: January 2020

The aim of the study was to establish the risks that contribute to social exclusion when receiving care by the elderly in the interaction of public services and the family in Central and Eastern Europe (Hungary as an example) and Russia. The article systematized the conceptual approaches to the elderly care system in the countries of Central and Eastern Europe (CEE) in comparison with applied in the Russian Federation. The risks that may contribute to exclusion of social groups from care services are discussed. These include: inaccessibility of social and medical services, low social standards and quality of life, poverty of the elderly population, poor development of the transport network in geographically remote regions of Russia, etc. When comparing social care systems, it was revealed that the overall objective of social policy regarding older people, is the provision of care in institutions and at home with clients, where the state plays a decisive role. It was determined that closer cooperation between the official system and family members in caring for the elderly, as well as support and the provision of services, provide a higher level of care, increase the competence of participants in the interaction in care and control over its process.
THE FRAGMENTATION OF POLITICAL REPRESENTATION AT MUNICIPAL LEVEL IN SLOVAK REPUBLIC IN PERIOD 2002 - 2018
Authors: KLUS MARTIN , MARTINKOVIČ MARCEL
Published: January 2020

Presented study sheds light on the developments of political representation at municipal level and tries to identify the sources of its fragmentation. These sources are vested in electoral laws, in development of national party system and in public distrust towards partisan candidates including changes in decision-making dynamics of the electorate. All mentioned factors shape the popular preference to support independent candidates in achieving municipal offices. This phenomenon gained on intensity between 2002 and 2018. The trend of ever-increasing support for civic and non-partisan candidates also introduces practical implications and risks in terms of lacking effective governing, transparency and of municipal policy control. Factors such as: non-existence of integrative organizational basis for political decision making, low levels of civic skills or elusive ownership structure of regional media. Most importantly, it is the inability of established political parties to maintain the functionality of democratic institutions in terms of public administration. All these factors increase the risks of decision-making at municipal level. Such development is part of deepening crisis of trust in political parties and leads to risks of forming a defect democracy.
Tolerance of Isolated Rabbit Hearts to Short Ischemic Periods Is Affected by Increased LV Mass Fraction
Authors: HLAVÁČOVÁ M. , OLEJNÍČKOVÁ V. , RONZHINA M. , STRAČINA T. , JANOUŠEK O. , NOVÁKOVÁ M. , BABULA P. , KOLÁŘOVÁ J. , PROVAZNÍK I. , PAULOVÁ H.
Published: January 2020

Hypertrophied hearts are known for increased risk of arrhythmias and are linked with reduced ischemic tolerance. However, still little is known about state characterized only by increased left ventricle (LV) mass fraction. Seventeen isolated rabbit hearts with various LV mass were divided into two groups according to LV weight/heart weight ratio (LVW/HW ratio), namely group H and L (with higher and lower LVW/HW ratio, respectively) and underwent three short cycles of global ischemia and reperfusion. The differences in electrogram (heart rate, QRSmax, mean number, onset and dominant form of ventricular premature beats) and in biochemical markers of myocardial injury (creatine kinase, lactate dehydrogenase – LDH) and lipid peroxidation (4-hydroxy-2-nonenal – 4-HNE) were studied. As compared to group L, hearts in group H exhibited lower tolerance to ischemia expressed as higher incidence and severity of arrhythmias in the first ischemic period as well as increase of LDH and 4-HNE after the first reperfusion. In the third cycle of ischemia-reperfusion, the preconditioning effect was observed in both electrophysiological parameters and LDH release in group H. Our results showed consistent trends when comparing changes in electrograms and biochemical markers. Moreover, 4-HNE seems to be good potential parameter of moderate membrane alteration following ischemia-reperfusion injury.
Nanofat 2.0: Experimental Evidence for a Fat Grafting Rich in Mesenchymal Stem Cells
Authors: LO FURNO D. , TAMBURINO S. , MANNINO G. , GILIA E. , LOMBARDO G. , TARICO M. S. , VANCHERI C. , GIUFFRIDA R. , PERROTTA R. E.
Published: January 2020

Different strategies have been developed in the last decade to obtain fat grafts as rich as possible of mesenchymal stem cells, so exploiting their regenerative potential. Recently, a new kind of fat grafting, called “nanofat”, has been obtained after several steps of fat emulsification and filtration. The final liquid suspension, virtually devoid of mature adipocytes, would improve tissue repair because of the presence of adipose mesenchymal stem cells (ASCs). However, since it is probable that many ASCs may be lost in the numerous phases of this procedure, we describe here a novel version of fat grafting, which we call “nanofat 2.0”, likely richer in ASCs, obtained avoiding the final phases of the nanofat protocol. The viability, the density and proliferation rate of ASCs in nanofat 2.0 sample were compared with samples of nanofat and simple lipoaspirate. Although the density of ASCs was initially higher in lipoaspirate sample, the higher proliferation rate of cells in nanofat 2.0 virtually filled the gap within 8 days. By contrast, the density of ASCs in nanofat sample was the poorest at any time. Results show that nanofat 2.0 emulsion is considerably rich in stem cells, featuring a marked proliferation capability.
Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?
Authors: BALLEKOVA J. , SOLTESOVA-PRNOVA M. , MAJEKOVA M. , STEFEK M.
Published: January 2020

The aim of this study was to investigate aldose reductase inhibitory action of setipiprant as a potential additional mechanism contributing to its anti-inflammatory action. Aldose reductase activity was determined by spectrophotometric measuring of NADPH consumption. Setipiprant was found to inhibit aldose reductase/NADPH-mediated reduction of 4-hydroxynonenal, 4-hydroxynonenal glutathione and prostaglandin H2 substrates, all relevant to the process of inflammation. Molecular modeling simulations into the aldose reductase inhibitor binding site revealed an interaction pattern of setipiprant. Considering multifactorial etiology of inflammatory pathologies, it is suggested that, in addition to the antagonizing prostaglandin D2 receptor, inhibition of aldose reductase may contribute to the reported anti-inflammatory action of setipiprant.
An Alternatively Activated Macrophage Marker CD163 in Severely Obese Patients: the Influence of Very Low-Calorie Diet and Bariatric Surgery
Authors: CINKAJZLOVÁ A. , LACINOVÁ Z. , KLOUČKOVÁ J. , KAVÁLKOVÁ P. , TRACHTA P. , KOSÁK M. , KRÁTKÝ J. , KASALICKÝ M. , DOLEŽALOVÁ K. , MRÁZ M. , HALUZÍK M.
Published: January 2020

CD163 is a marker of macrophages with anti-inflammatory properties and its soluble form (sCD163) is considered a prognostic predictor of several diseases including type 2 diabetes mellitus (T2DM). We explored sCD163 levels at baseline and after very low-calorie diet (VLCD) or bariatric surgery in 32 patients with obesity (20 undergoing VLCD and 12 bariatric surgery), 32 obese patients with T2DM (22 undergoing VLCD and 10 bariatric surgery), and 19 control subjects. We also assessed the changes of CD163 positive cells of monocyte-macrophage lineage in peripheral blood and subcutaneous adipose tissue (SAT) in subset of patients. Plasma sCD163 levels were increased in obese and T2DM subjects relative to control subjects (467.2±40.2 and 513.8±37.0 vs. 334.4±24.8 ng/ml, p=0.001) and decreased after both interventions. Obesity decreased percentage of CD163+CD14+ monocytes in peripheral blood compared to controls (78.9±1.48 vs. 86.2±1.31 %, p=0.003) and bariatric surgery decreased CD163+CD14+HLA-DR+ macrophages in SAT (19.4±2.32 vs. 11.3±0.90 %, p=0.004). Our data suggest that increased basal sCD163 levels are related to obesity and its metabolic complications. On the contrary, sCD163 or CD163 positive cell changes do not precisely reflect metabolic improvements after weight loss.
Hematological Profile of Untreated or Ionizing Radiation-Exposed Cyclooxygenase-2-Deficient Mice
Authors: HOFER M. , HOFEROVÁ Z. , DUŠEK L. , SOUČEK K. , GRUZDEV A.
Published: January 2020

We investigated hematopoiesis in untreated and ionizing radiation-exposed cyclooxygenase-2-deficient (COX-2 KO) mice. We performed a complex hematological analysis of 16 parameters in untreated COX-2 KO male mice or COX-2 KO male mice irradiated with the dose of 4 Gy of γ-rays and their wildtype littermates. At baseline, hematopoiesis was increased in COX-2-deficient mice, but attenuated by irradation in COX-2-deficient mice compared to wildtype. To conclude, the anti-inflammatory action of the COX-2 genetic disruption plays a positive role in hematopoiesis under basal conditions but is detrimental following radiation exposure.
The Effect of HT-2 Toxin on Ovarian Steroidogenesis and Its Response to IGF-I, Leptin and Ghrelin in Rabbits
Authors: KOLESAROVA A. , MARUNIAKOVA N. , KADASI A. , HALENAR M. , MARAK M. , SIROTKIN A. V.
Published: January 2020

T-2 toxin and its metabolite HT-2 toxin are one of the most toxic mycotoxins of type A-trichothecenes, which are produced mainly by Fusarium species. Therefore, study of Fusarium toxins T-2 toxin and HT-2 toxin is an essential issue because they could also play role in failures of reproductive functions as well as endocrine system of domestic animals. Assessment of the effect of A-trichothecene mycotoxin HT-2 toxin alone or combined with insulin-like growth factor (IGF-I), leptin and ghrelin on estradiol secretion by rabbit ovarian fragments in vitro was done. Rabbit ovarian fragments were incubated without (control group) or with HT-2 toxin, or its combinations with IGF-I, leptin and ghrelin at various concentrations for 24 h. Secretion of 17β-estradiol was determined by ELISA. Firstly, HT-2 toxin at the doses 10 and 100 ng.ml-1, but not at 1 ng.ml-1 decreased 17β-estradiol secretion by ovarian fragments. Secondly, 17β-estradiol secretion was not affected by HT-2 toxin exposure combined with growth factor IGF-I, metabolic hormones leptin and ghrelin. In conclusion, HT-2 toxin has potent direct dose-dependent effects on ovarian steroidogenesis in rabbits. These direct effects of HT-2 mycotoxin on ovarian steroidogenesis could impact negatively on the reproductive performance of rabbits.
Perancangan Enterprise Architecture Sistem Informasi dengan Menggunakan Framework TOGAF ADM pada CV. Garam Cemerlang
Authors: Soraya Virna , Sari Wellia Shinta
Published: January 2020

CV. Garam Cemerlang merupakan perusahaan manufaktur yang memproduksi berbagai jenis garam. Meskipun perusahaan ini sangat baik di bidang pembuatan garam, perusahaan ini hanya didukung oleh sistem keuangan yaitu menggunakan aplikasi krieshand untuk mengelola laporan keuangan. Aktivitas proses bisnis yang ada di perusahaan dilakukan secara manual dan hanya menggunakan Microsoft Office sebagai aplikasi untuk pencatatan data. Sehingga aktivitas terkait dengan pengadaan bahan baku, produksi, dan penjualan garam belum efisien dan mengakibatkan perusahaan mengalami keterlambatan dalam mengelola data. Tujuan penelitian ini adalah membuat perancangan enterprise architecture sistem informasi pengadaan bahan baku, produksi dan penjualan menggunakan TOGAF dengan metode ADM (Architecture Development Method) yang terdiri dari fase Preliminary, fase Requirement Management, fase Architecture Vision, fase Business Architecture, fase Information System Architecture, fase Technology Architecture, fase Opportunities and Solution, fase Migration Planning, dan fase Implementation Governance. Perencanaan enterprise architecture ini menghasilkan blueprint arsitektur bisnis, arsitektur sistem informasi, arsitektur teknologi, analisis gap pada setiap arsitektur, serta roadmap implementasi sistem informasi pada CV. Garam Cemerlang.Â Kata kunciâ€” Enterprise Architecture, TOGAF, Architecture Development Method, Sistem Informasi
TINGKAT KOMPETENSI ANDRAGOGIK LULUSAN PROGRAM STUDI S1 AGRIBISNIS UNIVERSITAS TERBUKA
Authors: Nurul Huda
Published: January 2020

Agricultural extension workers must have several competencies in order to do their job properly.One essential competence to master was related to their andragogic abilities, especially in mastering the concepts of extension and adult education.This research was intended to identify the andragogic competence of agricultural extension workers graduated from Universitas Terbuka (UT). The information of competence aspects such as knowledge, affective, and psychomotor were also collected to elaborate the findings. By using an explanatory research design, a survey technique was implemented among 111 agricultural extension workers who were graduated from UT in four different locations, namely Serang, Karawang, Cirebon, and Tanggamus. Data were collected by using questionnaire and analyzed by using descriptive statistics. In depth interview was also conducted to elaborate the findings. The findings indicated that agricultural extension workers graduated from UT generally had a medium level in their andragogic competence, either in implementing the concepts of extention or in adult education. Their level of knowledge and psychomotor was low, while their affective level were moderate.
TES PERFORMA DAN KECERDASAN MAJEMUK
Authors: Benny Agus Pribadi  , Sri Lestari
Published: January 2020

Learning paradigm had been shifted to "student centered in which teacher or instructor role is more as facilitators who help students develop optimal potential. In order to be effective teacher needs to better understand all potentials of students. One form of the potential is multiple intelligences. To determine the learning achievement, the assessment should cover multiple intelligence-based learning outcomes which are performance tests. Variety of performance tests can be used to assess the actual performance or learning outcomes achieved by students.
PEMAHAMAN KONSEP BILANGAN BULAT GURU SD DI PASIR JAMBU KABUPATEN BANDUNG
Authors: Permana Didi , Herman Tatang
Published: January 2020

This study aimed to identified the understanding of whole number concept among elementary school teacher taking distance course in Elementary Teacher Training Indonesia Open University as viewed from the quality of module, tutor performance, and learning motivation. Samples were 72 participants of tutorial program under Mathematics for Elementary School subject carried out in Pasir Jambu village Bandung Regency during 2012.1 registration period. Using questionaire, test concerning whole number concept, documentary study, observation and interview for data gathering. Results indicated that (i) module quality, tutor performance, and motivation contributed significantly toward whole number concept, the contribution number were 29,80%, 18,30% dan 29,80%, (ii)module quality and tutor performance contributed significantly to whole number concept (36,70%), (iii) tutor performance and motivation contributedsignificantly to whole number concept (38,70%), (iv) module quality, tutor performance and motivation contributed significantly to whole number concept (51,50%), and (v) the rest 48,50% was determined by unidentified variables. Recommends that tutorial administrator should maintain the quality of module and to enlarge student access upon learning material through media alternative, to improve tutor profesionalism, and to encourage motivation among studentconcerned.

 

Penelitian ini bertujuan mengidentifikasi pemahaman tentang konsep bilangan bulat kelompok guru SD peserta pendidikan guru jarak jauh ditinjau dari aspek kualitas modul, kinerja tutor dan motivasi belajar. Sampel adalah seorang tutor dan 72 mahasiswa peserta tutorial mata kuliah Pembelajaran Matematika SD di Kelompok Belajar Pasir Jambu Kabupaten Bandung masa registrasi 2012.1. Pengumpulan data dilaksanakan menggunakan angket, tes pemahaman konsep bilangan bulat, studi dokumentasi, observasi dan tes untuk tutor. Hasil penelitian menunjukkan bahwa (i) kualitas modul, kinerja tutor dan motivasi belajar secara bersama-sama berkontribusi secara signifikan terhadap pemahaman konsep bilangan bulat, yaitu masing-masing sebesar 29,80%, 18,30% dan 29,80%, (ii) kualitas modul dan kinerja tutor secara bersama-sama berkontribusi signifikan (36,70%) terhadap pemahaman konsep bilangan bulat, (iii) kinerja tutor dan motivasi belajar mahasiswa secara bersama-sama berkontribusi secara signifikan (38,70%) terhadap pemahaman konsep bilangan bulat, (iv) kualitas modul, kinerja tutor dan motivasi belajar mahasiswa bersama-sama berkontribusi secara signifikan (51,50%) terhadap pemahaman konsep bilangan bulat, dan (v) sisanya 48,50% ditentukan oleh variabel lain yang tidak diteliti. Disarankan hendaknya penyelenggara tutorial mempertahankan kualitas dan memperluas akses mahasiswa terhadap materi belajar, meningkatkan profesionalitas tutor, dan meningkatkan motivasi mahasiswa peserta tutorial.
Wpływ działalności małych przedsiębiorstw na rozwój regionalny. Przypadek województwa podkarpackiego
Authors: Grzęda Łukasz , Kozak Sylwester
Published: January 2020

Celem pracy jest zbadanie wpływu działalności małych przedsiębiorstw na wzrost gospodarczy w regionie na przykładzie powiatów w województwie podkarpackim. Badania wykazały, że zarówno wzrost liczby już działających, jak i wzrost liczby nowo zarejestrowanych małych przedsiębiorstw przyczyniają się pozytywnie do rozwoju gospodarczego powiatu mierzonego wartością ogólnej i przypadającej na jednego mieszkańca sprzedaży produkcji wytworzonej na terenie danego powiatu, a także liczbą zatrudnionych w nich pracowników. Badania wskazują również, że na wielkość produkcji przedsiębiorstw zlokalizowanych w danym powiecie pozytywny wpływ ma wzrost zrealizowanych nakładów inwestycyjnych, a także wzrostowy trend PKB w całym województwie. W badaniach wykorzystano dane z Banku Danych Lokalnych GUS za lata 2005-2016. Ocenę modeli prowadzono przy użyciu regresji panelowej.
Measurement and Assessment of the Level of Economic Development of the Counties of the Opolskie Voivodeship
Authors: Podstawka Marian , Suchodolski Bartłomiej
Published: January 2020

The publication presents the problems of local development on the example of counties in opolskie voivodeship. The aim of the article is an attempt to assess the level of diversification of economic development in the counties belonging to the opolskie voivodeship in 2010-2015. The evaluation of the level of counties development was carried out using Hellwig taxonomic development measure. The study confirmed the research hypothesis assuming the existence of diversification of economic development of the studied counties. The study showed the existence of a relatively constant diversification of the development of the counties in all of the analyzed years.
Strategic maturity desiderata of corporate capabilities - model ad its empirical veryfication
Authors: Nogalski Bogdan , Niewiadomski Przemysław
Published: January 2020

The subject of the research of this elaboration are strategic maturity desiderata of the corporate capability of manufacturing enterprises operating in the agricultural machinery sector. The vital goal of this study is to determine the level of partial (functional) maturities constituting the strategic capability of the investigated enterprises. Achieving the main objective required the formulation and implementation of partial goals, which were applied to outline: nomination of desiderata determining strategic maturity (literature query), compilation of the research model in the form of an assessment sheet (literature exploration and expert research) and recognition of the level of strategic maturity among manufacturers of the agricultural machinery sector (theoretical model validation). The considerations contained in the paper are embedded in social sciences, and more specifically; in the field of management and quality sciences.
A study on personality traits and shopping online
Authors: Usakli Hakan
Published: January 2020

The aim of the article is to analyze inter- relations between online shopping behaviour and personality traits. Online shopping has been developing all over the world. People not only buy locally but also trade internationally via the internet. The method of the study is correlation with the use of SPSS programme. Two different inventories were administrated to 243 university students via online. Big-Five Personality Questionnaire and Compulsive Online Shopping Behaviour were used. This test apparatus indicates five different personality dimensions such as extraversion, agreeableness, conscientiousness, emotional stability, intellect imagination. The compulsive online shopping behaviour was applied to get data on online shopping. The findings indicate that there are correlations between personality traits and excessive online shopping behaviour. People who are less agreeable and self conscious should think more before shopping online.
The Relationship between of the Learning Environment and the Higher Order Thinking Skills (HOTS) among Secondary School Students
Authors:   Pursuing Ph.D, School of Education and Modern Languages, College of Arts and Sciences (CAS), Universiti Utara, Malaysia., Omar Mohd Saifulkhair , Awang Mohd Isha ,   Associate Professor, School of Education and Modern Languages, College of Arts and Sciences (CAS), Universiti Utara, Malaysia.
Published: January 2020

: Malaysia's achievements in the TIMSS (Trends in International Mathematics and Science Study) and PISA (Program International Student Assessment) from 2007 to 2015 show a decline in the mastery of science and mathematics subjects among Malaysian students internationally (Shahril Sabudin, Azlin Norhaini Mansor, Subahan Mohd Meerah & Azliza Muhammad, 2018) [28]. Meanwhile, the science laboratory learning environment is found that can influence the student’s higher order thinking skills (HOTS). This finding is supported by Mubarok, Suprapto and Adam (2018)[21] who found that the investigative activities in the laboratory would influence the HOTS. However, there are still have no any studies that been found in Malaysia on the relationship between the science laboratory learning environment and the HOTS. Therefore, this study aims to know the relationship between of the learning environment and the HOTS among secondary school students in Kuala Nerus, Terengganu by using the quantitative method. There are two sections in the questionnaire form, which are part A regarding the science laboratory learning environment and part B on the student’s HOTS. The part A uses SLEI which was developed by Fraser et al. (1992) and the part B uses a set of subjective questions that was developed by the researchers. The researchers selected 89 students from two schools using a simple random sampling. The findings showed that there were a relationship between of the learning environment in the material environment and the student’s HOTS. The results of the study proved that the adequacy of materials and apparatus in science labs would enhance the student’s HOTS. The implications of this study enable the Ministry of Education Malaysia (MOE) to budget for the purchase of sufficient science materials and apparatus.
Front Administration: An Indispensable Unit of Hospital
Authors:   Research Scholar, CT University, Ludhiana, India., Juneja Mr. Shrikant , Singh Dr. Amrinder ,   Head: Faculty of Business, CT University, Ludhiana, India
Published: January 2020

The proposed study is an attempt to understand the linkage between the satisfaction level of the front-end employees and satisfaction level of the patients and attendants visiting the hospital for their IPD treatment. The study was executed in a three hundred bedded multispecialty hospital in Ludhiana. The study is highly significant as front administration plays a pivotal role in soothing the journey of the patients and leaves an indelible mark right from the registration counter to the admission, during their treatment and discharge. An integrated questionnaire was used in conducting the study. During the field plan of twenty days, hundred IPD patients were interviewed with simple random method. The next facet of study, twenty five front administration employees ranging from front office attendant, front office nurses and technicians were interviewed. The current study results revealed no significant relationship of satisfaction level of front end administration staff with satisfaction level of patients.
Age Factor– A Basic Parameter for Health Insurance- A Study with Special Reference to Chennai City among Standalone Health Insurers
Authors:   Director, AMET Business school, AMET University, Chennai., Meenakshisundaram Dr. K.S. , Krishnekumaar Dr. S T ,   Vice President, Indus ind bank, Chennai.
Published: January 2020

Age is a basic factor for any kind of insurance. and the premiums that are to be paid are based on Age. In India, the premiums are low for Health Insurance if the age of the proposer is less whereas the same is on the converse in case of United States including the Medic Aid or Obamacare. In case of Life Insurance, the age is the longevity factor whereas the same is the factor for Health Insurance in determining the cost and coverage. Hence to analyse the fact of Age with reference to insurance a research study was taken up and data were collected from 531 samples from salaried and business class relating to Banking, IT & IT enabled Services, Manufacturing sector in the city of Chennai relating to Standalone Health Insurers. The collected data were analysed with statistical tools and the results show that majority of the respondents were males and they are between 31-40 years of age.
Valid Arguments and Heyting Algebra using Multi Valued Logic
Authors:   Dept.of Mathematics, Sri Chandra Sekharendra Saraswathi Viswa Maha Vidyalaya, Kanchipuram, India., Malathi R. , Venugopal T. ,   Dept.of Mathematics, Sri Chandra Sekharendra Saraswathi Viswa Maha Vidyalaya, Kanchipuram, India.
Published: January 2020

Over last three decades, multi valued logic (MVL) has been receiving considerable attention. So, we focus our concentration upon multi valued logic using some of the rules of mathematical logic, which can be used in developing artificial intelligence. Since Aristotle’s logic there were only two propositions. Later it was extended to n-valued logical proposition which is greater than 2, that is popularly known as multi valued logic proposition – they are true, false and unknowns. In this paper we will discuss about multi valued logic with 27- possible using Jaina logic and some of the rules as it gives the best results. In Jaina Logic, indeterminant means something which cannot describe more than one aspect at a time. So, we are going to consider each aspect separately and assign True or False. Then according to the given condition we can either apply min or max condition to get a precise solution.
A Drawing Formalistic Aspects in School and Higher Learning Institutions
Authors:   Faculty of Innovative Design and Technology, UniSZA, Terengganu, Malaysia., Ibrahim* Marzuki , Razali Hartini M ,   Faculty of Art & Design, UiTM Machang Branch, Kelantan, Malaysia., Omar Mazni ,   Faculty of Art & Design, UiTM Machang Branch, Kelantan, Malaysia.
Published: January 2020

This research aims to identify formalistic aspects (design elements and principals) generally incorporated in school curriculum and the Faculty of Art & Design curriculum in creating drawings. Formalistic aspects present in drawings will be contrasted against each other via a special test conducted to selected respondents of two different phases – prior and after university enrollment, which involved of 105 respondents. They were Sijil Pelajaran Malaysia (SPM) candidates that have undergone interview test prior to the Faculty of Art & Design of Universiti Teknologi MARA (UiTM) Kelantan Branch September intake. During the second phase which was done after university enrollment, the same respondents were recruited to participate in the evaluation of their drawing skill. Currently, all respondents are at their second (02) semester in four programs offered at UiTM. Based on the analysis done to drawings created in the First Phase (before) and the Second Phase (after) university enrollment, several discoveries were made pertaining to the incorporation of formalistic aspects in drawing creation. From the results, several suggestions were presented. It is hoped that this work will lead to the improvement of the current high school curriculum in general and the curriculum of the Faculty of Art & Design, in particular, in order to ensure that art is elevated to a higher level in the face of future challenges.
An Efficient KP-ABE for Information Centric Networks
Authors:   Assistant Professor, K L University, Guntur (Andhra Pradesh), India., Rani* P. Jhansi , Kumar P. Ajay ,   K L University, Guntur (Andhra Pradesh), India., Devi P. Manasa ,   K L University, Guntur (Andhra Pradesh), India., Tejaswi B. Navya ,   K L University, Guntur (Andhra Pradesh), India.
Published: January 2020

With the obvious nature of distributed computing, Smart telephones could store/recuperate particular information from anyplace at any of point. Therefore, those information security issue on adaptable cloud swings out to an opportunity to be continuously totally serious and hinders support the difference in the versant cloud. There need help liberal examinations that bring been provoked enhance those cloud security. Make that concerning delineation it might, those more fantastic and just them are not appropriate for helpful cloud since Mobile telephones simply have bound figuring property Furthermore control. Plans for small complicated above are unbelievable essential to versant cloud arrangements. Here, we suggest a Efficient and secured information centres (ESIC) for versant scattered enlisting. It grasps KPABE, an entryway control progression utilized similarly as just customary cloud situation however variations those assembly about right controller tree to mark it sensible to flexible cloud conditions. ESIC changes a liberal share of complicated raised gets the chance to control the tree change for KP-ABE from mobile phones ought to separate go among waiters. Furthermore, should reducing the client disavowal cost, it familiarizes trademark depiction arenas for completing lethality forswearing, which is a thorny issue done extend constructed KP-ABE structures. The test goes something like the display that ESIC could viably diminish the overhead on the remote side at clients would give lion's share of the information in versant cloud conditions.
Energy Efficient Routing based on Reliability for Mobile Ad hoc Network
Authors:   Rresearch Scholar, M.Tech., Punjabi University, Patiala., Sidhu Er. Hashandeep Kaur , Patterh Manjeet Singh ,   Punjabi University, Patiala., Preeti  ,   Punjabi University, Patiala.
Published: January 2020

MANETs is a network which has nodes. Communication is done without use of infrastructure. Quality based routing is developed which considers end to end qualitatiove data communication. A number of protocols were designed and suggested by researchers to achieve effective communication in MANETs. Considering number of quality factors as energy, trust, bandwidth etc a number of protocols are existing. But still there are number of factors those can consider to enhance the performance of the protocols used for the communication purpose. The existing schemes were effective enough but still as factors those were considering only the resources held by a node not the physical factors were present as node is to survive and communication in network. So further enhancements were possible by considering the physical parameters. Inspired from that in this paper a proposed scheme considering physical factor name as Distance is considered as the improvement to the traditional scheme. The distance factor is behaving as finding the physical presence of the node in the network also the distance factor will help to find the appropriate node for the next hop to communicate. A simulation is conducted in MATLAB software and performance factors as throughput and energy are analyzed, also an comparison with existing system is done and the results shows that the proposed scheme is effective enough to achieve QOS based routing with reduced energy consumption and high throughput.
Solar PV Fed Irrigation Pump
Authors:   Professor and Head, Department in Electrical and Electronics, St.Joseph’s College of Engineering, Tamil Nadu, India., Pradeep* Jayarama , R.H Pearl Nightingale. ,   Research Assistant, Department of Electrical and Electronics Engineering, SSN College of Engineering, Chennai (Tamil Nadu), India., Deshpande Dr. Mrunal ,   Associate Professor, Department of Electrical and Electronics Engineering, SSN College of Engineering, Chennai (Tamil Nadu), India
Published: January 2020

Agricultural growth has been severely affected due to the constraints in irrigation-energy deficits. Due to the availability of abundant solar energy especially in India for all days, solar powered irrigation technology has been a promising alternative source compared to canonical electricity and diesel focused pumping systems. How to furnish an electric power suitable to drive an irrigation pump for agricultural purposes in isolated areas using solar PV panels is the problem. This project deals with solving a local irrigation problem in countries. In this proposed project a simple design of simulation and analysis of a PMSM fed by a solar PV, modelled through DC/DC converter controlled by a MPPT and for utilizing the power from Solar. Compared to all converters, luo converters is the advanced technology. POSL luo converter are of new DC-DC step-up converter. This POSL luo converter performs positive to positive DC-DC voltage increasing conversion. The hardware implementation has been done for positive output super-lift luo converter respectively.
Corporate Feed, Compact 2X2 Array Antenna With Enhanced Radiation Characteristics using Metamaterial Structure
Authors:   Research Scholar, Department of Mechanical Engineering, Rabindranath Tagor University, Bhopal, M.P, India., Shende* Pankaj , Somkuwar Dr. Vandana ,   Associate Professor, Department of mechanical engineering, national Institute of Technical Teacher Training and Research, Bhopal, M.P., Kancherla Dr.Praveen Kumar ,   Department of Electronics and Communication Engineering, CMR Institute of Technology, Hyderabad, India.
Published: January 2020

In current study, mushroom type metamaterial substrate is designed to operate at ISM band and is embedded in 2X2 array as a ground. Unique properties of mushroom type metamaterial substrate like as high impedance surface (HIS) helped in design of low aperture antenna, Artificial magnetic conductor (AMC) helps in enhancing the radiation characteristics and Forbidden band gap (FBG) helps in suppressing transverse electric (TE) and transverse magnetic (TM) wave propagation hence point of mutual coupling and side lobe levels are reduced. So, 2X2 array antenna with corporate feed resonating at 2.5GHz is embedded by array of mushroom type metamaterial unit cells is designed in HFSS and obtained results are compared with 2X2 array resonating at 2.5GHz on conventional conducting ground results. An enhancement in impedance band width of 2.47%, gain of 2.91dB and with lowered side lobe reduction of 3.74dB.
Waste Management Technique Applied in the Preparation of Bio Concrete Material
Authors:   Assistant Professor, Department of Industrial Biotechnology, Bharath Institute of Higher Education And Research, Chennai (Tamil Nadu), India., Kowsalya* E. , Rebecca Dr. L. Jeyanthi ,   Prof. & Head, Department of Industrial Biotechnology, Bharath Institute of Higher Education And Research, Chennai (Tamil Nadu), India.
Published: January 2020

Due to Modernization and urbanization constructing industries are fast growing also it leading to high demand of constructing materials because of expensive prices, and for the construction industry, usage of steel is currently limited heavily Many studies have been carried out to identify highly available, low cost innovative material to use in construction industry as a solution to meet the ever increasing demand for raw material. Bamboo was used as a construction material as a coarse aggregate, steel reinforcement. Bamboo has a higher compressive strength than wood, brick, or concrete and a tensile strength that rivals steel. water absorption in bamboo was the main problem used for construction .because The durability of the concrete is largely affected by absorption of water. Also poly ethylene bags are widely used in the country and its disposal after use causes more problems ,Mismanaged waste of polyethylene bags is the current threatening to the environment this waste is largely availbe its abundant high resistance to insects, fungi, animals, as well as molds, mildew, rot and many chemicals. In this study cubic bamboo was used as a coarse aggregate and it was coated with the waste LDPE bag melt ,as one of the coating material and other one is neem oil.and it was investigated to find the water absorption and turbidity, antifungal activity and compressive strength some other parameters in bamboo material with coatings it was observed that compared to untreated bamboo the polyethylenene coated bamboo material shows reduction in water absorption level and turbity.