bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential of Briquette Produced with Torrefied Agroforestry Biomass to Generate Energy
Authors: Reis Portilho Gabriel , Resende de Castro Vinicius , de Cássia Oliveira Carneiro Angélica , Cola Zanuncio José , José Vinha Zanuncio Antonio , Gabriella Surdi Paula , Gominho Jorge , de Oliveira Araújo Solange
Published: November 2020

Agroforestry industries, such as sugar-alcohol, food, and logging, produce large quantities of waste, used to generate energy from direct burning. The application of other processes, such as torrefaction and briquetting, can increase the profits from the use of agro-industrial waste for energy generation. Briquetting is an alternative for using these wastes, allowing the compaction of the biomass, generating a biofuel with high energy density, and which is more homogeneous and easier to store and transport. The objective of this study was to evaluate the physical and chemical properties of four biomass types (wastes from sawed eucalypt and pine wood, coffee pruning wastes, and sugarcane bagasse) torrefied at 300 °C and compacted (briquetting) at pressures of 6.21, 8.27, and 10.34 MPa. The torrefaction increased the fixed carbon content, ash, and calorific value, and reduced the volatile material content and hygroscopic equilibrium moisture of the biomasses. The volatile material content was lower and the fixed carbon higher in the coffee pruning waste, the ash content higher in the sugarcane bagasse, and the calorific value higher in the pine and eucalypt wood. The briquetting and the torrefaction processes increased the biomass bulk density, and the useful calorific value, respectively, and consequently the energy density of the briquettes produced with torrefied raw material under high pressure. The mechanical properties of the briquettes produced with all materials increased with the compaction pressure. Torrefaction and briquetting increased the energy potential of the biomasses evaluated to produce energy from clean technology.
Studies into Fungal Decay of Wood In Ground Contact—Part 1: The Influence of Water-Holding Capacity, Moisture Content, and Temperature of Soil Substrates on Fungal Decay of Selected Timbers
Authors: Marais Brendan Nicholas , Brischke Christian , Militz Holger , Peters Johann Hinrich , Reinhardt Lena
Published: November 2020

This article presents the results from two separate studies investigating the decay of wood in ground contact using adapted versions of laboratory-based terrestrial microcosm (TMC) tests according to CEN/TS 15083-2:2005. The first study (A) sought to isolate the effect of soil water-holding capacity (WHCsoil [%]) and soil moisture content (MCsoil [%WHCsoil]) on the decay of five commercially important wood species; European beech (Fagus sylvatica), English oak heartwood (Quercus robur), Norway spruce (Picea abies), Douglas-fir heartwood (Pseudotsuga menziesii), and Scots pine sapwood (Pinus sylvestris), while keeping soil temperature (Tsoil) constant. Combinations of soil mixtures with WHCsoil of 30%, 60%, and 90%, and MCsoil of 30%, 70%, and 95%WHCsoil were utilized. A general trend showed higher wood decay, measured in oven-dry mass loss (MLwood [%]), for specimens of all species incubated in soils with WHCsoil of 60% and 90% compared to 30%. Furthermore, drier soils (MCsoil of 30 and 70%WHCsoil) showed higher MLwood compared to wetter soils (95%WHCsoil). The second study (B) built on the first’s findings, and sought to isolate the effect of Tsoil and MCsoil on the decay of European beech wood, while keeping WHCsoil constant. The study used constant incubation temperature intervals (Tsoil), 5–40 °C, and alternating intervals of 10/20, 10/30, and 20/30 °C. A general trend showed drier MCsoil (60%WHCsoil), and Tsoil of 20–40 °C, delivered high wood decay (MLwood > 20%). Higher MCsoil (90%WHCsoil) and Tsoil of 5–10 °C, delivered low wood decay (MLwood < 5%). Alternating Tsoil generally delivered less MLwood compared to their mean constant Tsoil counterparts (15, 20, 25 °C). The results suggest that differences in wood species and inoculum potential (WHCsoil) between sites, as well as changes in MCsoil and Tsoil attributed to daily and seasonal weather patterns can influence in-ground wood decay rate.
Mitigation of Nickel Toxicity and Growth Promotion in Sesame through the Application of a Bacterial Endophyte and Zeolite in Nickel Contaminated Soil
Authors: Naveed Muhammad , Bukhari Syeda Sosan , Mustafa Adnan , Ditta Allah , Alamri Saud , El-Esawi Mohamed A. , Rafique Munazza , Ashraf Sobia , Siddiqui Manzer H.
Published: November 2020

Nickel (Ni) bioavailable fraction in the soil is of utmost importance because of its involvement in plant growth and environmental feedbacks. High concentrations of Ni in the soil environment, especially in the root zone, may retard plant growth that ultimately results in reduced plant biomass and yield. However, endophytic microorganisms have great potential to reduce the toxicity of Ni, especially when applied together with zeolite. The present research work was conducted to evaluate the potential effects of an endophytic bacterium Caulobacter sp. MN13 in combination with zeolite on the physiology, growth, quality, and yield of sesame plant under normal and Ni stressed soil conditions through possible reduction of Ni uptake. Surface sterilized sesame seeds were sown in pots filled with artificially Ni contaminated soil amended with zeolite. Results revealed that plant agronomic attributes such as shoot root dry weight, total number of pods, and 1000-grains weight were increased by 41, 45, 54, and 65%, respectively, over control treatment, with combined application of bacteria and zeolite in Ni contaminated soil. In comparison to control, the gaseous exchange parameters (CO2 assimilation rate, transpiration rate, stomatal- sub-stomatal conductance, chlorophyll content, and vapor pressure) were significantly enhanced by co-application of bacteria and zeolite ranging from 20 to 49% under Ni stress. Moreover, the combined utilization of bacteria and zeolite considerably improved water relations of sesame plant, in terms of relative water content (RWC) and relative membrane permeability (RMP) along with improvement in biochemical components (protein, ash, crude fiber, fat), and micronutrients in normal as well as in Ni contaminated soil. Moreover, the same treatment modulated the Ni-stress in plants through improvement in antioxidant enzymes (AEs) activities along with improved Ni concentration in the soil and different plant tissues. Correlation and principal component analysis (PCA) further revealed that combined application of metal-tolerant bacterium Caulobacter sp. MN13 and zeolite is the most influential strategy in alleviating Ni-induced stress and subsequent improvement in growth, yield, and physio-biochemical attributes of sesame plant.
Unpacking the ‘Business Model’ for Fortification Initiatives in Low- and Middle-Income Countries: Stakeholder Identified Drivers of Success and Constraints to Progress
Authors: Lalani Baqir , Ndegwa Michael , Bennett Ben
Published: November 2020

Background: Initiatives to tackle micronutrient deficiencies (MNDs) in low-and middle-income countries (LMICs) have increased steadily in recent years. Commodities such as staple foods (e.g., cereals) and condiments (e.g., salt) have been targeted as ‘vehicles’ for industrial fortification through numerous projects and initiatives. However, mixed experiences with delivery, coverage and sustainability have been found. Methods: Using an online survey of 71 key stakeholders (from 35 countries) consisting of the public/private sector, academia and civil society, this study sought to unpack the ‘business model’ for fortification initiatives to identify the key drivers of success and constraints faced by stakeholders in LMICs. Bivariate analysis was conducted to identify factors associated with the coverage of the target market and the perceived success and sustainability of fortification initiatives. Results: We identified four key factors contributing to the success of fortification initiatives. The first involves the size of the firm. Large firms had a significantly higher (p 0.05) self-sustaining index (perceived level of sustainability of the fortification initiative) than smaller sized firms. In addition, a higher perceived success score (p 0.05) was associated with non-targeted initiatives compared to those specifically targeted at a certain cohort of the population, further illustrating the benefits of producing at scale. Secondly, a significant relationship was found between whether standards were enacted and the coverage of the target market by the project/firm (p 0.05).). The third key factor relates to the ability to source adequate testing for the fortified produce in-house. A positive correlation was found for post-mix in-factory testing and the self-sustaining index (p 0.05). Finally, delays to importation and high charges were cited as key constraints to the use of premix. Conclusions: We argue therefore that a successful ‘business model’ for industrial fortification initiatives invariably consist of: (i) the involvement of larger sized firms that have the advantage of benefiting from economies of scale; (ii) the availability and application of agreed standards by the producer; (iii) high quality assurance/compliance monitoring (including post-mix testing where relevant), and; (iv) the ability to procure premix in a timely/cost-effective manner. These criteria are likely to be important factors that contribute to the success of fortification initiatives in LMICs.
Small Subcutaneous Soft Tissue Tumors (<5 cm) Can Be Sarcomas and Contrast-Enhanced Ultrasound (CEUS) Is Useful to Identify Potentially Malignant Masses
Authors: De Marchi Armanda , Pozza Simona , Charrier Lorena , Cannone Filadelfo , Cavallo Franco , Linari Alessandra , Piana Raimondo , Geniò Irene , Balocco Paolo , Massè Alessandro
Published: November 2020

Subcutaneous masses smaller than 5 cm can be malignant, in contrast with the international guidelines. Ultrasound (US) and magnetic resonance imaging (MRI) are useful to distinguish a potentially malignant mass from the numerous benign soft tissue (ST) lesions. Contrast-enhanced ultrasound (CEUS) was applied in ST tumors, without distinguishing the subcutaneous from the deep lesions. We evaluated CEUS and MRI accuracy in comparison to histology in differentiating malignant from nonmalignant superficial ST masses, 50% smaller than 5 cm. Sensitivity, specificity, and positive and negative predictive values (PPV, NPV) with their 95% confidence intervals (CI) were calculated. Of malignant cases, 44.4% measured ≤5 cm. At univariate analysis, no statistically significant differences emerged between benign and malignant tumors in relation with clinical characteristics, except for relationship with the deep fascia (p = 0.048). MRI accuracy: sensitivity 52.8% (CI 37.0, 68.0), specificity 74.1% (CI 55.3, 86.8), PPV 73.1% (CI 53.9, 86.3), and NPV 54.1% (CI 38.4, 69.0). CEUS accuracy: sensitivity 75% (CI 58.9, 86.3), specificity 37% (CI 21.5, 55.8), PPV 61.4% (CI 46.6, 74.3), and NPV 52.6% (CI 31.7, 72.7). CEUS showed a sensitivity higher than MRI, whereas PPV and NPV were comparable. Also, masses measuring less than 5 cm can be malignant and referral criteria for centralization could be revised.
The Association of Post-Materialism with Health Care Use. Findings of a General Population Survey in Germany
Authors: Hajek André , König Hans-Helmut
Published: November 2020

(1) The aim of this study was to identify the association between post-materialism and health care use (in terms of the frequency of doctor visits and the reason for doctor visits). (2) Data were taken from the German General Social Survey (a representative sample of individuals aged 18 years and over, n = 3338). The Inglehart’s post-materialist index was used to quantify post-materialism. The doctor visits (self-reported) in the past three months served as an outcome measure. The reasons for seeing a doctor served as an additional outcome measure (acute illness; chronic illness; feeling unwell; requesting advice; visit to the doctor’s office without consulting the doctor (e.g., need to get a prescription); preventive medical check-up/vaccination). (3) After adjusting for several covariates, negative binomial regressions revealed that compared with materialism, post-materialism was associated with decreased doctor visits (total sample; women). Moreover, the likelihood of visiting the doctor for reasons of chronic illnesses was lower in post-materialistic women, whereas the likelihood of visiting the doctor for reasons of preventive medical check-up/vaccination was higher in post-materialistic women. (4) Study findings identify an unexplored link between post-materialism and doctor visits in women. One may conclude that in the long-term, the increased likelihood of preventive medical check-ups in post-materialistic women will be beneficial in decreasing the need for doctor visits for reasons of chronic illnesses. However, future research is required to elucidate the underlying mechanisms.
Alcohol and Betting Radio Advertising in Spain. A Comparative Analysis of the Minor’s Protection Time Slot from a Media Responsibility Perspective
Authors: Perelló-Oliver Salvador , Muela-Molina Clara , Romero-Rodríguez Luis M.
Published: November 2020

This research analyzes the presence of advertising and radio mentions of alcoholic beverages and sports betting, two products that represent harmful behaviors for the audiences’ health. To do this, a quantitative content analysis was undertaken for all of the programming of the three most listened radio stations in Spain (Cadena Ser, COPE, and Onda Cero) throughout 2017, obtaining a total corpus of 2848 radio messages distributed as follows: 266 radio spots and 2582 radio mentions. The messages were also analyzed according to the broadcasting schedules (protected time-slot or non-protected time-slot). The results showed that advertising and sports betting mentions were more present in the regular programming of the three stations (n = 2304), with mentions (n = 2582) being more numerous than advertising spots (n = 544). Moreover, it is evident that in practice, none of the radio stations respected the protected time slots since the majority of the mentions and spots of high alcoholic beverages and sports bets were verified between 6:00–21:59 (n = 2522). These results show the prevailing need for greater control over this type of content by public entities, demonstrating a significant lack of regulation by the media’s self-control mechanisms.
Nursing Students’ Attitudes towards Immigrants’ Social Rights
Authors: Sánchez-Ojeda María Angustias , Navarro-Prado Silvia , Martín-Salvador Adelina , Luque-Vara Trinidad , Fernández-Gómez Elisabet , Plaza del Pino Fernando Jesús
Published: November 2020

The migrant population has increased in recent years and, as a result, so has cultural diversity. Universities are incorporating specific modules addressing cultural diversity. However, the native population has negative attitudes towards immigrants, as they believe that immigrants receive more social benefits and abuse healthcare services. Nurses may have these attitudes too, which may affect the way they treat patients. The objective of this study was to determine nursing students’ attitudes towards the rights of the migrant population. This is a descriptive ex post facto study using a cross-sectional design, with 821 nursing students in Melilla, Ceuta, and Almeria, Spain. An anonymous questionnaire was used for data collection. Students recognize the same rights for both the immigrant and native populations. More than 80% of the sample upholds the right of undocumented immigrants and their families to access publicly funded healthcare. Attitudes were more positive among students with a Berber background and first-year students. Students approved of the right of immigrants and their families to healthcare and education. The students’ negative attitudes towards the social rights of immigrants need to be addressed with intercultural training to reduce their prejudices as future professionals in a multicultural society.
Attitudes of Polish Seniors toward the Use of Public Space during the First Wave of the COVID-19 Pandemic
Authors: Fabisiak Beata , Jankowska Anna , Kłos Robert
Published: November 2020

The number of seniors rises worldwide. The lockdown of public institutions caused by COVID-19 influenced the lives of many of them. In the new reality, owners and managers of public spaces need to rethink the way they provide their services, and redesign public spaces to meet the needs of senior citizens. This requires the recognition of the needs of seniors concerning the use of public spaces in the times of the COVID-19 hazard. To investigate this issue, survey studies with 1000 respondents aged 65+ were conducted. The implementation of the obtained data in the process of redesigning public spaces may facilitate the opening up after the lockdown. Taking into account the requirements of a very large group of citizens being seniors is crucial, as it was found that 55% of respondents will also be afraid to use public spaces after the COVID-19 lockdown. The selected ideas that could minimize the feeling of fear when using public spaces after the lockdown were evaluated by seniors.
Timing of Spheno-Occipital Synchondrosis Ossification in Children and Adolescents with Cleft Lip and Palate: A Retrospective Case-Control Study
Authors: Vale Francisco , Francisco Inês , Lucas António , Roseiro Ana , Caramelo Francisco , Sobral Adriana
Published: November 2020

Background: Cleft lip and palate (CLP) can affect the development of the maxilla; which may create a midfacial deficiency as well as an interference of the facial growth pattern and dentofacial esthetics. Objective: This study aimed to estimate the chronological age of complete fusion of the spheno-occipital synchondrosis (SOS) in cleft lip and palate patients and a control group; using cone beam computed tomography (CBCT) images. Methods: In this retrospective study; 125 patients were enrolled (cleft lip and palate group (n = 91); control group (n = 34)). Age comparison was made with a chi-square test; and a Kaplan–Meier analysis determined the median time to reach complete fusion of the spheno-occipital synchondrosis (p < 0.05). Results: The experimental group showed statistically significant differences in the median time for complete ossification between males and females (p = 0.019). The median time for complete ossification of the spheno-occipital synchondrosis was; for males; 15.0 years in both groups; for females; it was 14.0 years and 13.0 years in the experimental group and in the control group; respectively. Both for males and females; there were no statistically significant differences between experimental and control groups (p = 0.104). Conclusions: The present study showed no differences in the ossification of the spheno-occipital synchondrosis between individuals with and without cleft lip and/or palate.
Screening Model for Estimating Undiagnosed Diabetes among People with a Family History of Diabetes Mellitus: A KNHANES-Based Study
Authors: Ryu Kwang Sun , Kang Ha Ye Jin , Lee Sang Won , Park Hyun Woo , You Na Young , Kim Jae Ho , Hwangbo Yul , Choi Kui Son , Cha Hyo Soung
Published: November 2020

A screening model for estimating undiagnosed diabetes mellitus (UDM) is important for early medical care. There is minimal research and a serious lack of screening models for people with a family history of diabetes (FHD), especially one which incorporates gender characteristics. Therefore, the primary objective of our study was to develop a screening model for estimating UDM among people with FHD and enable its validation. We used data from the Korean National Health and Nutrition Examination Survey (KNHANES). KNAHNES (2010–2016) was used as a developmental cohort (n = 5939) and was then evaluated in a validation cohort (n = 1047) KNHANES (2017). We developed the screening model for UDM in male (SMM), female (SMF), and male and female combined (SMP) with FHD using backward stepwise logistic regression analysis. The SMM and SMF showed an appropriate performance (area under curve (AUC) = 76.2% and 77.9%) compared with SMP (AUC = 72.9%) in the validation cohort. Consequently, simple screening models were developed and validated, for the estimation of UDM among patients in the FHD group, which is expected to reduce the burden on the national health care system.
Hedging against Neuropathic Pain: Role of Hedgehog Signaling in Pathological Nerve Healing
Authors: Moreau Nathan , Boucher Yves
Published: November 2020

The peripheral nervous system has important regenerative capacities that regulate and restore peripheral nerve homeostasis. Following peripheral nerve injury, the nerve undergoes a highly regulated degeneration and regeneration process called Wallerian degeneration, where numerous cell populations interact to allow proper nerve healing. Recent studies have evidenced the prominent role of morphogenetic Hedgehog signaling pathway and its main effectors, Sonic Hedgehog (SHH) and Desert Hedgehog (DHH) in the regenerative drive following nerve injury. Furthermore, dysfunctional regeneration and/or dysfunctional Hedgehog signaling participate in the development of chronic neuropathic pain that sometimes accompanies nerve healing in the clinical context. Understanding the implications of this key signaling pathway could provide exciting new perspectives for future research on peripheral nerve healing.
Can Larvae of Forest Click Beetles (Coleoptera: Elateridae) Feed on Live Plant Roots?
Authors: Kozlov Mikhail V. , Prosvirov Alexander S. , Zvereva Elena L.
Published: November 2020

The life histories of many soil-dwelling invertebrates remain poorly studied. The larvae of two click beetle species, Athous subfuscus and Dalopius marginatus, which are most abundant in European boreal forests, are both classified as omnivorous and are included in lists of root-damaging pests. Nevertheless, we are not aware of any direct proof of their ability (or inability) to consume plant roots. In this study, we asked whether these larvae actually feed on the roots of forest plants in the absence of other food sources. Live roots of boreal forest plants, including trees (Betula pubescens, Picea abies and Pinus sylvestris) and grass (Deschampsia flexuosa), were offered to click beetle larvae in a two-month microcosm experiment. The weight of roots placed in vials with the wireworms did not decrease, indicating that the larvae of these click beetle species did not feed on live roots, even in the absence of other food sources. This suggests that the feeding niches of A. subfuscus and D. marginatus larvae are narrower than previously thought and do not include live plant tissues. Therefore, these click beetle species should be excluded from the lists of forest pests damaging tree roots.
Isavuconazole: Mechanism of Action, Clinical Efficacy, and Resistance
Authors: Ellsworth Misti , Ostrosky-Zeichner Luis
Published: November 2020

Increasing incidence of invasive fungal infections combined with a growing population of immunocompromised hosts has created a rising need for antifungal agents. Isavuconazole, a second-generation broad-spectrum triazole with activity against yeasts, dimorphic fungi, and molds, has a favorable safety profile and predictable pharmacokinetics. Patients typically tolerate isavuconazole well with fewer drug–drug interactions. Clinical trials have found it to be noninferior to voriconazole for invasive aspergillosis, an alternative therapy for salvage treatment of mucormycosis, and suitable for stepdown therapy with invasive candidiasis. Cross-resistance with other triazoles is common. More studies are needed to determine the role of isavuconazole in anti-mold prophylaxis in high-risk patients.
Estimation of Coal’s Sorption Parameters Using Artificial Neural Networks
Authors: Skiba Marta , Młynarczuk Mariusz
Published: November 2020

This article presents research results into the application of an artificial neural network (ANN) to determine coal’s sorption parameters, such as the maximal sorption capacity and effective diffusion coefficient. Determining these parameters is currently time-consuming, and requires specialized and expensive equipment. The work was conducted with the use of feed-forward back-propagation networks (FNNs); it was aimed at estimating the values of the aforementioned parameters from information obtained through technical and densitometric analyses, as well as knowledge of the petrographic composition of the examined coal samples. Analyses showed significant compatibility between the values of the analyzed sorption parameters obtained with regressive neural models and the values of parameters determined with the gravimetric method using a sorption analyzer (prediction error for the best match was 6.1% and 0.2% for the effective diffusion coefficient and maximal sorption capacity, respectively). The established determination coefficients (0.982, 0.999) and the values of standard deviation ratios (below 0.1 in each case) confirmed very high prediction capacities of the adopted neural models. The research showed the great potential of the proposed method to describe the sorption properties of coal as a material that is a natural sorbent for methane and carbon dioxide.
Structure of Alloys for (Sm,Zr)(Co,Cu,Fe)z Permanent Magnets: II. Composition, Magnetization Reversal, and Magnetic Hardening of Main Structural Components
Authors: Dormidontov Andrey G. , Kolchugina Natalia B. , Dormidontov Nikolay A. , Milov Yury V. , Andreenko Alexander S.
Published: November 2020

Experimental series of alloys for (Sm,Zr)(Co,Cu,Fe)Z permanent magnets are presented in the concentration ranges that provide wide variations of (4f)/(4d)/(3d) ratios of comprising elements. Optical metallographic analysis, observation of the surface domain structure upon magnetization reversal (Kerr effect), electron microprobe analysis, and measuring the major hysteresis loops of samples at different stages of heat treatment are used to study processes related to the development of the highly coercive state of these samples. It was found that the volume fractions of two main structural components A and B, which comprise 90% of the total sample volume, rigorously control the coercivity at all stages of thermal aging. At the same time, structural components A and B themselves in samples being in the high-coercivity state differ qualitatively and quantitatively in the chemical composition, domain structure and its development in external magnetic fields and, therefore, are characterized by different morphologies of the phases comprising the structural components. Two stages of phase transformations in the sample structure are observed. During isothermal annealing, the cellular structure develops within the B component, whereas, during stepwise (slow) cooling or quenching from the isothermal aging temperature to 400 °C, a phase structure evolves within both the cell boundaries in B and the structural component A. The degree of completion of the phase transformations within micro- and nano-volumes of the components determines the ultimate hysteretic characteristics of the material.
Strengthening of Concrete Column by Using the Wrapper Layer of Fibre Reinforced Concrete
Authors: Koteš Peter , Vavruš Martin , Jošt Jozef , Prokop Jozef
Published: November 2020

Structures and bridges are being designed on the proposed and requested design lifetime of 50 to 100 years. In practice, one can see that the real lifetime of structures and bridges is shorter in many cases, in some special cases extremely shorter. The reasons for the lifetime shortening can be increased of the load cases (e.g., due to traffic on bridges, or due to other uses of a structure), using the material of lower quality, implementation of new standards and codes according to Eurocode replacing older ones. During the whole lifetime the structures must be maintained to fulfil the code requests. If the constructions are not able to fulfil the Ultimate Limit States (ULS) and the Serviceability Limit State (SLS), the structures or bridges have to be strengthened (whole or its elements). The purpose of the paper is the presentation of using a layer of the fibre concrete for a columns’ strengthening. Using the fibre reinforced concrete (FRC) of higher tensile strength makes it possible to increase the load-bearing capacity of the cross-section the column. The contact between the old concrete (core of column) and newly added layer (around column) is very important for using that method of strengthening. In the article, there is also a comparison of the surface modification methods.
The Effect of pH on the Size of Silver Nanoparticles Obtained in the Reduction Reaction with Citric and Malic Acids
Authors: Marciniak Lukasz , Nowak Martyna , Trojanowska Anna , Tylkowski Bartosz , Jastrzab Renata
Published: November 2020

In colloidal methods, the morphology of nanoparticles (size and shape) as well as their stability can be controlled by changing the concentration of the substrate, stabilizer, adding inorganic salts, changing the reducer/substrate molar ratio, and changing the pH and reaction time. The synthesis of silver nanoparticles was carried out according to the modified Lee and Meisel method in a wide pH range (from 2.0 to 11.0) using citric acid and malic acid, without adding any additives or stabilizers. Keeping the same reaction conditions as the concentration of acid and silver ions, temperature, and heating time, it was possible to determine the relationship between the reaction pH, the type of acid, and the size of the silver nanoparticles formed. Obtained colloids were analyzed by UV-Vis spectroscopy and investigated by means of Transmission Electron Microscope (TEM). The study showed that the colloids reduced with citric acid and malic acid are stable over time for a minimum of seven weeks. We observed that reactions occurred for citric acid from pH 6.0 to 11.0 and for malic acid from pH 7.0 to 11.0. The average size of the quasi-spherical nanoparticles changed with pH due to the increase of reaction rate.
Facile Use of ZnO Nanopowders to Protect Old Manual Paper Documents
Authors: Motelica Ludmila , Popescu Aurelian , Răzvan Anca-Gabriela , Oprea Ovidiu , Truşcă Roxana-Doina , Vasile Bogdan-Stefan , Dumitru Florina , Holban Alina-Maria
Published: November 2020

One of the main problems faced by libraries, archives and collectors is the mold degradation of the paper-based documents, books, artworks etc. Microfungi (molds) emerge in regular storage conditions of such items (humidity, usually over 50%, and temperatures under 21 °C). If the removal of the visible mycelium is relatively easy, there is always the problem of the subsequent appearance of mold as the spores remain trapped in the cellulosic, fibrillary texture, which acts as a net. Moreover, due to improper hand hygiene bacteria contamination, old books could represent a source of biohazard, being colonized with human pathogens. An easy and accessible method of decontamination, which could offer long term protection is therefore needed. Here, we present a facile use of the ZnO nanopowders as antimicrobial agents, suitable for cellulose-based products, conferring an extended antibacterial and anti-microfungal effect. The proposed method does not adversely impact on the quality of the cellulose documents and could be efficiently used for biodegradation protection.
Burn Care in the Greek and Roman Antiquity
Authors: Wallner Christoph , Moormann Eric , Lulof Patricia , Drysch Marius , Lehnhardt Marcus , Behr Björn
Published: November 2020

The last century brought about more rapid new developments in the treatment of burns, which significantly lowered the mortality of burn injuries. However, burns were already treated in antiquity, where the threshold from spirituality to scientific medicine originated. The existing literature on burn treatment is very limited and there are many cross-references, some of them incorrect. The aim of this work by an interdisciplinary team of historians and physicians is to offer a more precise reproduction of the burn treatment of Greek and Roman antiquity using original texts in context and with a modern scientific background. There are many sources from ancient doctors on the subject of burn treatment, as well as the treatment of burned-out wounds and frostbite, which have not yet been mentioned. The literature research also showed an understanding of scientific contexts in ancient medicine, such as antiseptics or rheology. Interestingly, there was a change in burn medicine from everyday Greek medicine to Roman military medicine with other burn patterns. The care of patients using analgetics and the therapy of burn shock arose from the literature. The ancient world is considered to be the foundation of medicine, but it is believed to have been based mainly on shamanism rather than science. However, already more than two millennia ago, burns were correctly assessed and treated according to today’s scientific standards and scientific relationships were recognized.
Direct-Write Spray Coating of a Full-Duplex Antenna for E-Textile Applications
Authors: Zhou Ying , Soltani Saber , Li Braden M. , Wu Yuhao , Kim Inhwan , Soewardiman Henry , Werner Douglas H. , Jur Jesse S.
Published: November 2020

Recent advancements in printing technologies have greatly improved the fabrication efficiency of flexible and wearable electronics. Electronic textiles (E-textiles) garner particular interest because of their innate and desirable properties (i.e., conformability, breathability, fabric hand), which make them the ideal platform for creating wireless body area networks (WBANs) for wearable healthcare applications. However, current WBANs are limited in use due to a lack of flexible antennas that can provide effective wireless communication and data transfer. In this work, we detail a novel fabrication process for flexible textile-based multifunctional antennas with enhanced dielectric properties. Our fabrication process relies on direct-write printing of a dielectric ink consisting of ultraviolet (UV)-curable acrylates and urethane as well as 4 wt.% 200 nm barium titanate (BT) nanoparticles to enhance the dielectric properties of the naturally porous textile architecture. By controlling the spray-coating process parameters of BT dielectric ink on knit fabrics, the dielectric constant is enhanced from 1.43 to 1.61, while preserving the flexibility and air permeability of the fabric. The novel combination textile substrate shows great flexibility, as only 2 N is required for a 30 mm deformation. The final textile antenna is multifunctional in the sense that it is capable of operating in a full-duplex mode while presenting a relatively high gain of 9.12 dB at 2.3 GHz and a bandwidth of 79 MHz (2.260–2.339 GHz) for each port. Our proposed manufacturing process shows the potential to simplify the assembly of traditionally complex E-textile systems.
Recent Advances in the Fabrication and Application of Graphene Microfluidic Sensors
Authors: Wu Shigang , Wang Xin , Li Zongwen , Zhang Shijie , Xing Fei
Published: November 2020

This review reports the progress of the recent development of graphene-based microfluidic sensors. The introduction of microfluidics technology provides an important possibility for the advance of graphene biosensor devices for a broad series of applications including clinical diagnosis, biological detection, health, and environment monitoring. Compared with traditional (optical, electrochemical, and biological) sensing systems, the combination of graphene and microfluidics produces many advantages, such as achieving miniaturization, decreasing the response time and consumption of chemicals, improving the reproducibility and sensitivity of devices. This article reviews the latest research progress of graphene microfluidic sensors in the fields of electrochemistry, optics, and biology. Here, the latest development trends of graphene-based microfluidic sensors as a new generation of detection tools in material preparation, device assembly, and chip materials are summarized. Special emphasis is placed on the working principles and applications of graphene-based microfluidic biosensors, especially in the detection of nucleic acid molecules, protein molecules, and bacterial cells. This article also discusses the challenges and prospects of graphene microfluidic biosensors.
Near-Infrared Organic Phototransistors with Polymeric Channel/Dielectric/Sensing Triple Layers
Authors: Kim Taehoon , Lee Chulyeon , Kim Youngkyoo
Published: November 2020

A new type of near-infrared (NIR)-sensing organic phototransistor (OPTR) was designed and fabricated by employing a channel/dielectric/sensing (CDS) triple layer structure. The CDS structures were prepared by inserting poly(methyl methacrylate) (PMMA) dielectric layers (DLs) between poly(3-hexylthiophene) (P3HT) channel layers and poly[{2,5-bis-(2-octyldodecyl)-3,6-bis-(thien-2-yl)-pyrrolo[3,4-c]pyrrole-1,4-diyl}-co-{2,2′-(2,1,3-benzothiadiazole)-5,5′-diyl}] (PODTPPD-BT) top sensing layers. Two different thicknesses of PMMA DLs (20 nm and 50 nm) were applied to understand the effect of DL thickness on the sensing performance of devices. Results showed that the NIR-OPTRs with the CDS structures were operated in a typical n-channel mode with a hole mobility of ca. 0.7~3.2 × 10−4 cm2/Vs in the dark and delivered gradually increased photocurrents upon illumination with an NIR light (905 nm). As the NIR light intensity increased, the threshold voltage was noticeably shifted, and the resulting transfer curves showed a saturation tendency in terms of curve shape. The operation of the NIR-OPTRs with the CDS structures was explained by the sensing mechanism that the excitons generated in the PODTPPD-BT top sensing layers could induce charges (holes) in the P3HT channel layers via the PMMA DLs. The optically modulated and reflected NIR light could be successfully detected by the present NIR-OPTRs with the CDS structures.
Fabrication of Infrared-Compatible Nanofluidic Devices for Plasmon-Enhanced Infrared Absorption Spectroscopy
Authors: Le Thu Hac Huong , Matsushita Takumi , Ohta Ryoichi , Shimoda Yuta , Matsui Hiroaki , Kitamori Takehiko
Published: November 2020

Nanofluidic devices have offered us fascinating analytical platforms for chemical and bioanalysis by exploiting unique properties of liquids and molecules confined in nanospaces. The increasing interests in nanofluidic analytical devices have triggered the development of new robust and sensitive detection techniques, especially label-free ones. IR absorption spectroscopy is one of the most powerful biochemical analysis methods for identification and quantitative measurement of chemical species in the label-free and non-invasive fashion. However, the low sensitivity and the difficulties in fabrication of IR-compatible nanofluidic devices are major obstacles that restrict the applications of IR spectroscopy in nanofluidics. Here, we realized the bonding of CaF2 and SiO2 at room temperature and demonstrated an IR-compatible nanofluidic device that allowed the IR spectroscopy in a wide range of mid-IR regime. We also performed the integration of metal-insulator-metal perfect absorber metamaterials into nanofluidic devices for plasmon-enhanced infrared absorption spectroscopy with ultrahigh sensitivity. This study also shows a proof-of-concept of the multi-band absorber by combining different types of nanostructures. The results indicate the potential of implementing metamaterials in tracking several characteristic molecular vibrational modes simultaneously, making it possible to identify molecular species in mixture or complex biological entities.
Subacute Ingestion of Caffeine and Oolong Tea Increases Fat Oxidation without Affecting Energy Expenditure and Sleep Architecture: A Randomized, Placebo-Controlled, Double-Blinded Cross-Over Trial
Authors: Zhang Simeng , Takano Jiro , Murayama Norihito , Tominaga Morie , Abe Takashi , Park Insung , Seol Jaehoon , Ishihara Asuka , Tanaka Yoshiaki , Yajima Katsuhiko , Suzuki Yoko , Suzuki Chihiro , Fukusumi Shoji , Yanagisawa Masashi , Kokubo Toshio , Tokuyama Kumpei
Published: November 2020

Ingesting oolong tea or caffeine acutely increases energy expenditure, and oolong tea, but not caffeine, stimulates fat oxidation. The acute effects of caffeine, such as increased heart rate and interference with sleep, diminish over 1–4 days, known as caffeine tolerance. During each 14-day session of the present study, 12 non-obese males consumed oolong tea (100 mg caffeine, 21.4 mg gallic acid, 97 mg catechins and 125 mg polymerized polyphenol), caffeine (100 mg), or placebo at breakfast and lunch. On day 14 of each session, 24-h indirect calorimetry and polysomnographic sleep recording were performed. Caffeine and oolong tea increased fat oxidation by ~20% without affecting energy expenditure over 24-h. The decrease in the respiratory quotient by oolong tea was greater than that by caffeine during sleep. The effect of oolong tea on fat oxidation was salient in the post-absorptive state. These findings suggest a role of unidentified ingredients in oolong tea to stimulate fat oxidation, and this effect is partially suppressed in a postprandial state. Two weeks of caffeine or oolong tea ingestion increased fat oxidation without interfering with sleep. The effects of subacute ingestion of caffeine and oolong tea differed from the acute effects, which is a particularly important consideration regarding habitual tea consumption.
Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence
Authors: Padial-Jaudenes Maria , Castanys-Munoz Esther , Ramirez Maria , Lasekan John
Published: November 2020

Palm oil/olein (PO/POL) is used in infant formulas to imitate the fatty acid profile of human milk (HM) and achieve similar levels of palmitic acid (PA). However, the positions of fatty acids on the triacylglyceride differ between PO/POL and HM, which affect fat absorption and produce unintended physiological consequences. Recent papers have reviewed evidence for physiological benefits of PO/POL and beta-palmitate (sn-2-palmitate) in infant formulas. The aim of the present review is to supplement the assessment of available clinical evidence on the physiological effects of PO/POL formulas in healthy infants. We intend to focus on PO/POL and not on sn-2-palmitate, since the latter was recently extensively reviewed. Clinical evidence supports that PO/POL in infant formulas leads to a lower fat, DHA, palmitate and calcium absorption, and bone mineralization; soft stools; and growth (weight accretion) compared to formulas without PO/POL. Consequently, it seems prudent to be considerate and cautious when adding PO/POL to infant formulas. While HM is the gold standard for infant nutrition, the development of infant formula should be based on achieving positive physiological outcomes, rather than just replicating HM nutrient composition.
Increasing Expiratory Hydrogen in Lactose Intolerance Is Associated with Additional Food Intolerance/Malabsorption
Authors: Schnedl Wolfgang J. , Meier-Allard Nathalie , Lackner Sonja , Enko Dietmar , Mangge Harald , Holasek Sandra J.
Published: November 2020

Single and/or combined food intolerance/malabsorption may cause nonspecific, functional gastrointestinal (GI) complaints. In lactose-intolerant patients we evaluated the influence of additional food intolerance/malabsorption with hydrogen (H2) breath tests. In a retrospective analysis of charts from 279 lactose-intolerant patients, we found 128 patients with only lactose intolerance (LIT). Then, we identified 106 LIT patients with additional histamine intolerance (HIT). Additionally, 45 LIT and HIT patients also had fructose malabsorption (FM). A hydrogen (H2) breath test was performed to evaluate LIT and FM. A serum diamine oxidase value of <10 U/mL and a response to a histamine-reduced diet was used to identify HIT. Using pairwise comparison with the Kruskal–Wallis test to associate the area under the curve (AUC) of LIT patients and, LIT with HIT, to LIT with HIT and FM it was found, that the exhaled hydrogen values were significantly higher in patients with two-fold and triple combined food intolerance/malabsorption (p < 0.004 and p < 0.001, respectively). Within the pool of 170 LIT patients with >20 ppm increase of expiratory H2 from baseline, there were 74 LIT-only patients, 60 LIT with HIT patients, and 36 LIT patients with additional HIT and FM. With the Kruskal–Wallis test AUCs demonstrated a significant difference between all three groups (p = 0.024). In patients with LIT, the presence of additional food intolerance/malabsorption, significantly increases expiratory H2 values. We demonstrate evidence, which may suggest HIT to embody an own GI disorder as food intolerance/malabsorption.
Effect of Cocoa and Cocoa Products on Cognitive Performance in Young Adults
Authors: Martín María Angeles , Goya Luis , de Pascual-Teresa Sonia
Published: November 2020

Increasing evidence support a beneficial role of cocoa and cocoa products on human cognition, particularly in aging populations and patients at risk. However, thorough reviews on the efficacy of cocoa on brain processes in young adults do not exist precisely due to the limited number of studies in the matter. Thus, the aim of this study was to summarize the findings on the acute and chronic effects of cocoa administration on cognitive functions and brain health in young adults. Web of Science and PubMed databases were used to search for relevant trials. Human randomized controlled studies were selected according to PRISMA guidelines. Eleven intervention studies that involved a total of 366 participants investigating the role of cocoa on cognitive performance in children and young adults (average age ≤25 years old) were finally selected. Findings from individual studies confirm that acute and chronic cocoa intake have a positive effect on several cognitive outcomes. After acute consumption, these beneficial effects seem to be accompanied with an increase in cerebral blood flow or cerebral blood oxygenation. After chronic intake of cocoa flavanols in young adults, a better cognitive performance was found together with increased levels of neurotrophins. This systematic review further supports the beneficial effect of cocoa flavanols on cognitive function and neuroplasticity and indicates that such benefits are possible in early adulthood.
Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function
Authors: Hertzler Steven R. , Lieblein-Boff Jacqueline C. , Weiler Mary , Allgeier Courtney
Published: November 2020

Consumer demand for plant protein-based products is high and expected to grow considerably in the next decade. Factors contributing to the rise in popularity of plant proteins include: (1) potential health benefits associated with increased intake of plant-based diets; (2) consumer concerns regarding adverse health effects of consuming diets high in animal protein (e.g., increased saturated fat); (3) increased consumer recognition of the need to improve the environmental sustainability of food production; (4) ethical issues regarding the treatment of animals; and (5) general consumer view of protein as a “positive” nutrient (more is better). While there are health and physical function benefits of diets higher in plant-based protein, the nutritional quality of plant proteins may be inferior in some respects relative to animal proteins. This review highlights the nutritional quality of plant proteins and strategies for wisely using them to meet amino acid requirements. In addition, a summary of studies evaluating the potential benefits of plant proteins for both health and physical function is provided. Finally, potential safety issues associated with increased intake of plant proteins are addressed.