bluuebunny/crossref_metadata_2025 huggingface dataset:
INVESTIGATION OF THE RELATIONSHIP BETWEEN ENTREPRENEURIAL TENDENCY AND ENTREPRENEURIAL PERSONALITY TRAITS OF STUDENTS IN THE FIELD OF HEALTH SCIENCES
Authors: UZUNTARLA Yasin , BAYER Nükhet , ŞAHİN İsmet
Published: March 2022

This research was conducted to examine the entrepreneurial tendencies and entrepreneurial personality traits of undergraduate and associate degree students studying in the field of health sciences. The universe of the descriptive study consisted of all undergraduate and associate degree students studying in the field of health sciences at a private university in Ankara, Turkey. It was aimed to reach the whole universe without selecting a sample, while 57% of the students (n=1004) participated in the research. The data of the study were obtained by using the "Socio-demographic Characteristics Form", "Entrepreneurship Tendency Scale" and "Entrepreneurial Personality Characteristics Scale". T-test, ANOVA, Post Hoc Tukey Test, Pearson Correlation Analysis and simple linear regression analysis were employed in the analysis of the data. Students' Entrepreneurial Tendency scale score (3.11±0.32) and Entrepreneurial Personality Scale score (3.24±0.27) were found to be moderate. Significant differences were observed in the entrepreneurial tendency and entrepreneurial personality traits of the students according to age, gender, parental occupation, family economic status, geographical region and education level. It was found that there was a significant positive correlation between the entrepreneurial tendency of the students and their entrepreneurial personality traits, and that the entrepreneurial personality of the students affected the level of entrepreneurial tendency (p<0.05). This follows that an entrepreneurship course should be included in university education and students should be supported to make projects in order to increase entrepreneurship activities, which are important in social development.
USING VIRTUAL MANIPULATIVES TO SUPPORT STUDENTS WITH DISABILITIES IN MATHEMATICS: A REVIEW OF LITERATURE
Authors: TERZİOĞLU Nesime Kübra , YIKMIŞ AHMET
Published: March 2022

The development of technology and changes in the understanding of education have increased the use and importance of virtual manipulatives in teaching mathematical concepts and skills to students with special needs. The aim of this research is to examine studies in which virtual manipulatives are used in teaching mathematics to students with special needs. For this purpose, the literature was searched and 16 studies meeting the criteria were included in the study. These studies were evaluated in terms of the year and journal were published, participants, application/intervention, mathematics subjects and methodological features. The data obtained as a result of these evaluations were analyzed with descriptive analysis, and the findings were interpreted by giving graphics and tables. When the graphics and tables were examined, it was seen that the virtual manipulative studies in special education were mostly published in the journals indexed in the "Social Sciences Citation Index (SSCI)" in 2020. Participants of these studies consist of three male students with learning disabilities, mostly between the ages of 13-15. Single case research methods were used in these studies. Additionally, it has been observed in the studies that are examined the effectiveness of virtual manipulatives or is compared the effectiveness of virtual and concrete manipulatives. For future research; It is recommended to analyze studies published in different languages and include other research methods.
THE ART OF TRADITIONAL STICKING AND ITS LAST REPRESENTATIVES IN SİVAS
Authors: Saklavcı Fatmagül
Published: March 2022

Carving, processing and ornamentation of wood, which is a material suitable for use with its strength and texture since prehistoric times, and is called woodworking. Stick making, is one of the traditional handicrafts of Sivas province and dates back to the 18th century, is one of the types of woodworking. Stick making, also known as mouthpiece maker, is a branch of art in which items such as mouthpieces, pens, nameplates, crochet handles, candlesticks, and ballpoint pens are prepared by embroidering on wooden materials. The main material traditionally used in stick making is obtained from the "germişek" tree grown in Sivas, Tokat, Erzincan, Kars and Ağrı. The reason for choosing this tree is that its branches are suitable for carving and absorb toxic substances into it. The tree has been taken under protection due to its decline in nature, and today poplar and hornbeam trees are used instead. The sticks, bark is peeled off in the logging machine, are cut and shaped according to the product to be made than the painting and polishing processes, ornaments are made with silk and wheat stalks. Today, there are only a few masters and workshops dealing with stick making in Sivas. In this study, a research has been made about this art and its current status by visiting the masters' workshops. One of these masters, Abdulkaya Yazarlı and his brothers are trying to keep this art alive, they learned and inherited from their father. They learned art from their father Ferit Usta. His master is Sheikh Aziz Baba who is also known as "Çubukçu Baba" is one of the spiritual personalities of the city and he is the most important representative of art in Sivas in the last century. Ferit Usta, by working on Sivas mouthpieces as an alternative to the painted mouthpieces made in Bilecik, developed the work of embroidery with thread and stems and created a style unique to Sivas. Since embroidering with thread is a laborious and time-consuming process, there are almost no people who do this work today. Nowadays craftsmen, who try to survive by working in difficult conditions in narrow spaces, cannot find apprentices who will teach and sustain their profession. In order for art to survive and be passed on to future generations, it is necessary to support people who set their heart on this work and to provide suitable conditions.
JM-17 Induces G0/G1 Cell Cycle Arrest in Human Breast Cancer Cells through the Downregulation of Androgen Receptors and Cyclin-Dependent Kinase 4 Protein Expression
Authors: Lai Guan-Yi , Chan Hardy , Chen Tzu-Chi , Lee Wen-Jui , Ho Yuan-Soon
Published: March 2022

Background:

Locally advanced breast cancer (BC) remains a clinical challenge for patients as many will eventually develop distant metastases despite receiving appropriate therapies.

Materials and Methods:

In this study, we have analyzed the expression of androgen receptors (AR) in a series of BC cell lines and found their expressions rather ubiquitous across many different cell lines. Moreover, we have demonstrated that JM-17 [(1E,4Z,6E)-4-(cyclobutylmethyl)-1,7-bis (3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one], a synthetic curcumin derivative, exhibited suitable antitumor activities on most of the BC cell lines tested.

Results:

Human MDA-MB-231 cells were treated with JM-17, and the results demonstrated that JM-17-induced cell cycle proliferation arrested at the G0/G1 phase in a dose-dependent manner. Cell cycle-regulated proteins, such as cyclin-dependent kinases 4 (CDK4), were downregulated and p21 was upregulated. We further demonstrated that JM-17 treatment reduced AR expressions in MDA-MB-231 cells. The AR/CDK4 protein complex was demonstrated for the first time using a fluorescence resonance energy transfer (FRET) activity assay and immunohistochemistry (IHC) staining. JM-17 reduced the FRET activity in vitro. An in vivo study further demonstrated that JM-17 (20 mg/kg) decreased considerably MDA-MB-231 xenograft tumor growth.

Conclusion:

AR-mediated BC formation is a factor that clinicians often neglect. Our study demonstrated that JM-17 could be a promising agent against specific targets in AR-positive BC patients.
Clinical Presentation of Advanced Extragonadal Embryonal Carcinoma Mimicking Classical Hodgkin Lymphoma
Authors: Liu Wei-Nung , Yu Tsung-Ying
Published: March 2022

A 22-year-old man presented with a 2-week history of abdominal pain, fatigue, fever, and night sweats. Enlarged neck and paraaortic lymph nodes were noted, but no testicular lesions were found using imaging tools. Pathology revealed poorly differentiated embryonal carcinoma (EC) of the metastatic neck lymph node. The patient presented with clinical symptoms similar to Hodgkin lymphoma (HL), but the final diagnosis was advanced-stage extragonadal EC. To our knowledge, this is a rare case report of EC presenting as classic HL.
Neutropenic Necrotizing Enterocolitis
Authors: Chin Chih-Ching , Shiau Junping , Lou Chi-Wen , Pan Mei-Ren , Chen Fang-Ming , Hou Ming-Feng
Published: March 2022

Neutropenic enterocolitis can occur after aggressive chemotherapy with a wide range of severity from mild to life threatening. Neutropenic necrotizing enterocolitis (NNE) is a catastrophic condition that has rarely been discussed in the literature. Here, we present the case of a 27-year-old previously healthy female who was diagnosed with acute myeloid leukemia and underwent a first course of chemotherapy. Severe neutropenia, high fever, and abdominal pain were noted 5 days later. After medical treatment had failed, emergent laparotomy was performed. Several patches of transmural necrosis were seen at the jejunum, and resection with primary anastomosis was done. However, more newly formed necrotic patches were found over the small bowel during second-look surgery 2 days later. This report emphasizes that NNE is an irreversible ongoing process refractory to medical or surgical treatments, and physicians should be cautious of this syndrome when using aggressive chemotherapy.
Immune-related Neuromuscular Junction Disorder after Immune Checkpoint Inhibitor Treatment
Authors: Peng Shang-Hsuan , Shao Yu-Yun
Published: March 2022

Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and prolonged the survival of patients with various malignancies. Nevertheless, the expanded usage of ICIs is associated with increased reports of immune-related adverse events (irAEs), some of which can impair functional outcomes and worsen the prognosis. We present a fatal case of a patient presenting with progressive generalized weakness diagnosed with immune-related neuromuscular junction (NMJ) disorder after nivolumab treatment. By describing this case, we hope to raise awareness of rare irAEs such as immune-related NMJ disorder because prompt intervention is essential to minimize long-term sequelae and improve outcomes.
Clinical Features, Prognostic Factors, and Treatment Outcomes in 611 Patients with Phyllodes Tumors of the Breast
Authors: Lin Chun Hui , Yang Po-Sheng , Chang Yuan-Ching , Ko Wen-Ching , Lam Hung-Bun , Wu Pao-Shu
Published: March 2022

Background:

Phyllodes tumors are uncommon biphasic breast tumors for which clinical findings remain insufficient to determine the optimal management strategy. The aim of this study was to report our experience of the clinicopathological features, prognostic factors, surgical treatment, and outcomes of patients presenting with phyllodes tumors in two different periods.

Materials and Methods:

We retrospectively reviewed the clinical and pathological data of 611 patients with histologically proven phyllodes tumors. The patients were separated into two groups: Period A, those who were treated from January 2006 to August 2013, and period B, those who were treated from September 2013 to September 2019. Clinical characteristics, histopathologic parameters, and outcomes were collected from patient records, and parameters were compared between the two periods.

Results:

The median follow-up was 7 months (range 0.5–84) in treatment period A and 14 months (range 0.5–118) in treatment period B. The median age was 38 years (range 12–75) in treatment period A and 40 years (range 12–79) in treatment period B. Analysis of the two treatment periods revealed an increase in tumor size at the diagnosis from 3.6 cm during period A to 4.5 cm during period B (P = 0.001). Most tumors were found in the upper outer quadrant, with an equal propensity to occur in either breast (34.6% vs. 42.2%). The pathologic diagnoses included 419 benign, 97 borderline, and 40 malignant lesions. Sixty cases (20 in period A and 40 in period B) experienced recurrence after surgery, including 35 benign phyllodes tumors (43% vs. 57%), 16 borderline tumors (38% vs. 63%), and 9 malignant tumors (44% vs. 56%) in either period (P = 0.003). Three cases (0.5%) (1 in period A and 2 in period B) had pulmonary metastases (0.3% vs. 0.7%). Multivariable linear regression analysis revealed that tumor size and a positive or undetermined surgical margin were the independent predictors of recurrence (P = 0.006, 0.020, and 0.004, respectively).

Conclusion:

Breast-conserving surgery with clear margins is technically feasible and a safe treatment for phyllodes tumors, but this strategy does not effectively further reduce local recurrence. Our findings demonstrated that clinical characteristics, tumor size, surgical margin, and pathologic features are the important predictors for tumor recurrence in patients with phyllodes tumors.
Skin Metastasis of a p16-Positive Squamous Cell Carcinoma Mimicking Radiation Recall Dermatitis
Authors: Shen Chia-Wei , Chen Jo-Pai , Hsueh Fu-Jen , Leung Henry Wing-Cheung
Published: March 2022

Radiation recall dermatitis is an acute inflammatory reaction confined to previously irradiated skin that occurs after the administration of certain drugs. Herein, we report the case of a 48-year-old man irradiated for bilateral supraclavicular and right axillary lymph nodal metastases from p16-positive esophageal or occult head-and-neck squamous cell carcinoma (SCC). Several months after the completion of radiotherapy, systemic therapy with a combination of methotrexate and pembrolizumab was commenced. The patient developed increased skin pigmentation and inflammation generally consistent with the region that had previously been irradiated. The skin reaction progressed with a protruding mass after prednisolone treatment. A biopsy confirmed p16-positive SCC. Systemic therapy was given, but the patient died 2 months after the confirmation of skin metastasis. We believe that ionizing radiation can modulate the tissue microenvironment of skin and subsequently promote carcinogenesis. It may also alter the tissue response to anticancer therapy, including anti-programmed death-1/PD-ligand 1. Corticosteroids may worsen the skin lesions and conflict with immunotherapy.
Long-term Remission by Nivolumab Monotherapy for Sorafenib-Refractory Hepatocellular Carcinoma
Authors: Chen Chia-Yu , Bai Li-Yuan
Published: March 2022

Hepatocellular carcinoma (HCC) is considered to be a relatively chemotherapy-resistant tumor. There was no standard systemic therapy for patients with metastatic HCC until 2007 when sorafenib was demonstrated to be superior to supportive care. Lenvatinib has also been used as a first-line choice since a randomized phase III noninferiority trial was conducted in 2018. In the second-line setting, regorafenib was the first drug to be approved for sorafenib-refractory advanced HCC. Other drugs such as cabozantinib and ramucirumab have also shown benefits in a second-line setting. Immunotherapy is another novel and well-tolerated treatment option for patients who are refractory to tyrosine kinase inhibitors. Here, we present a patient with HCC which progressed after sorafenib treatment, and who subsequently achieved a nearly complete remission after nivolumab monotherapy. Maintenance therapy with nivolumab every 2–3 months was prescribed to sustain the good response based on a previous study that used rituximab maintenance therapy in a patient with follicular lymphoma.
Pembrolizumab as a Bridge to Autologous Stem Cell Transplantation in Refractory Gray Zone Lymphoma
Authors: Tsai Chun-Kuang , Ko Po-Shen , Chen San-Chi
Published: March 2022

Gray zone lymphoma (GZL), a rare type of B-cell lymphoma (BCL), has features between diffuse large BCL and classical Hodgkin lymphoma (cHL) and an unfavorable outcome. The expression of PD-L1, encoded by chromosome 9p24.1, has been positively correlated with the copy number alteration of 9p24.1, and it has been associated with a high response rate to anti-PD-1 treatment in cHL and primary mediastinal large BCL (PMBCL). GZL shares similar genomic alterations with cHL and PMBCL, and thus, it may also respond well to anti-PD-1 treatment. However, little is known about the efficacy of anti-PD-1 treatment and the predictive role of PD-L1 expression in GZL. Here, we present a case of GZL refractory to first-line chemotherapy. The patient had a high expression of PD-L1 and was successfully treated with pembrolizumab as a salvage treatment, followed by autologous stem cell transplantation (ASCT) in January 2018. The patient still had a complete metabolic response 42 months after ASCT.
System for Analysis and Prediction of Trends in Cryptocurrency Market
Authors: Ansari Shaad Iqbal , H Y Vani
Published: March 2022

In this article forecasting of daily closing price series of Bitcoin, Ripple, Dash, Litecoin and Ethereum crypto currencies, using data on prices (open, low, high), market capital and volumes using prior days is focused. The value conduct of cryptographic forms of money remains to a great extent neglected, giving new chances to scientists and business analysts to feature the likenesses and contrasts with standard monetary costs. Hence the paper is focused on this area. he results are compared with various benchmarks. Predictions are done using statistical techniques and machine learning algorithms. A simple linear regression (SLR) model that uses only a single-variable sequence of closing prices for forecasting, and a multiple linear regression (MLR) model that uses a multivariate sequence of prices and quantities at the same time. The simple linear regression (SLR) model for univariate serial forecasting uses only closing prices. Mean Absolute Percentage Error (MAPE) and relative Root Mean Square Error (relative RMSE) performance measures are considered. The accuracy achieved by the ARIMA model on our dataset is the highest, followed by Multivariable Linear Regression and LSTM.
PENGARUH PEMAHAMAN LITERASI DIGITAL DAN PEMANFAATAN MEDIA PEMBELAJARAN TERHADAP KOMPETENSI PEDAGOGIK GURU ERA DIGITAL LEARNING
Authors: Sulistyarini Winda , Fatonah Siti
Published: March 2022

Era digital merupakan era di mana semua aspek dalam kehidupan, termasuk proses pembelajaran lebih banyak memanfaatkan media digital. Era digital tidak dapat dipisahkan dengan kemampuan literasi, literasi digital merupakan kunci dan fondasi utama yang harus dimiliki. Untuk mendukung aktifitas literasi digital dari peserta didik, dibutuhkan media pembelajaran yang inovatif. Kedua hal tersebut merupakan modal dalam meningkatkan kompetensi pedagogik guru pada era digital learning. Kompetensi pedagogik dapat dipahami sebagai kemampuan guru mengelola pembelajaran. Kompetesi pedagogik juga menentukan keberhasilan proses pembelajaran. Penelitian ini berjenis kuantitatif, penelitian ini dimaksudkan untuk mencari adakah pengaruh literasi digital guru terhadap pemanfaatan media pembelajaran dan kompetensi pedagogik guru di SMP Negeri 2 Nusawungu. Subjek pada penelitian ini ialah guru di SMPN 2 Nusawungu, Cilacap. Analisis data penelitian ini menggunakan analisis SPSS. Hasil penelitian ini yakni pemahaman literasi digital guru, serta pemanfaatan media pembelajaran berpengaruh positif dan signifikan secara simultan terhadap kompetensi pedagogik guru era digital learning di SMP Negeri 2 Nusawungu. Dari hasil pengujian menunjukkan coefficient hasil regresi X1, X2, terhadap Y yaitu R sebesar 0,765>0,05, sehingga terdapat pengaruh pemahaman literasi digital guru, pemanfaatan media pembelajaran terhadap kompetensi pedagogik guru. Dan pada hasil output model summary nilai R2 sebesar 0,585, sehingga dapat disimpulkan bahwa pemahaman literasi digital guru dan pemanfaatan media pembelajaran mampu meningkatkan nilai variabel kompetensi pedagogik guru sebesar 58,5%. Adapun, sisanya 41,5% dipengaruhi oleh faktor-faktor lain di luar regresi.
Instalação de Módulos Python com pip
Authors: Gibbs Fred
Published: March 2022

Há muitas formas de se instalar bibliotecas externas de Python; esta lição explica um dos métodos mais comuns usando pip.
Change and Continuity in Children's Services
Authors: Parker Roy
Published: March 2022

This collection of twelve new and revised essays on child care and children’s services gives a unique and lasting review of child care services, explaining significant political, economic, legal and ideological aspects of this history from the mid-1850s.
The Problems of the Imam and the Islamic Preacher in the Western World
Authors: Hussein Alaaeldin Mostafa Abdalla , Chourana Mohamed
Published: March 2022

Praise be to Allah the Lord of the worlds and may the blessings and peace of Allah be upon the most honored of messengers our master Muhammad and upon all his family and companions. One of the greatest and most honorable jobs on the earth is the position of the Imam and the caller to God, because it is the job of the prophets and messengers, may the blessings of God be upon them all, the imams is God's vicegerent on the earth. for that , and we will talk in this research paper about the extent of the difficulties and problems faced by imams In the Mosques there in the Western world, and what hinders them towards conveying this great message, and working to find solutions to advance the sector of imams in the Western world.
The Effects on National Sovereignty in Light of the Growth of Illegal Immigration in Libya
Authors: Husien Ayoub Anwar Almabrok , Abdesalam El Fatih Abdullahi , Zaroum Abdulhamid Mohamed Ali
Published: March 2022

This paper aims to highlight the effects of the illegal immigration on the Libyan national sovereignty. The researcher used both inductive method and comparative method to identify and clarify the violation of the national sovereignty with the growing of the phenomenon of illegal immigration, and to study to what extent illegal immigration phenomenon is associated with the national sovereignty violation. The research focused on the Libyan case as it is the nearest country to the European shores; in addition to the presence of human smuggling rings which work, uncontrolled on the Libyan territories, to facilitate the illegal immigration to the European ports for money, which in turn affects the Libyan sovereignty, its stable security, and its commitments to the international treaties and conventions. On the other hand, the illegal immigration might constitute a flagrant violation of the national sovereignty, as the presence of human smuggling rings, money-laundering, and organ trafficking rings might cause disruption of many of the international relations between Libya and its international partners, since Libya is among the countries that have signed the international conventions on the illegal immigration. The researcher achieved several results, including: the national sovereignty might be affected as the human smuggling rings and money launderers constitute a significant threat by circumventing the prohibitions and the restrictions to facilitate the illegal immigration to the European shores for money.
Strengthening Water Security between the Preservation and Development of Water Resources in the Light of the Prophet’s Sunnah An Objective Study
Authors: Al Balloushi Saleh Abdelkarim
Published: March 2022

When we find great care at all levels in water security, an important question comes to mind: Does the Sunnah care about rooting water security issues and vocabulary? Does it have a clear picture of conservation of water resources? Does it have a revealing statement for ways to develop water? This research came to clarify the prophetic hadiths related to water security in terms of preserving water resources, and the most prominent ways to develop and increase them. One of the results of the research: that water security in fact revolves around ways to sustain water wealth, and that it is closely related to other types of security such as food security, and it is one of the pillars of the development and prosperity of countries, and its absence is one of the challenges for human societies. It also resulted in the Prophetic Sunnah invoking the status and importance of water, by making it the first means of purification, preventing its monopoly, indicating that it is one of the blessings that a person will be asked about on the Day of Resurrection, and its call to conserve water through measures that call for the optimal use of water, and distance from polluting water. And everything that wastes and spoils water, as well as ways to enhance, develop and provide water wealth through keenness on acts of obedience and water alms, encouragement of digging wells and conducting streams, in addition to rain and thankfulness for the blessing of water.
The Shiite Expansion in Kenya: History, Causes and Theological Methods
Authors: Mohamed Mohamed Sheikh Alio
Published: March 2022

This research sheds light on the Shiite expansion in Kenya; History, Causes and its theological methods to preach Shiism. Its statement of problem and importance comes from lack of academic studies which address the threats of Shiite expansion in Kenya and its sectarian and social impacts on the Sunni Muslims in Kenya, which necessitated such research and the likes of academic studies. The research consists of an abstract and four sections. The first section defines Shiism and its most important beliefs, while the second addresses the history of Shiites arrival to Kenya, whereas the third displays the causes of the Shiite expansion in Kenya. The fourth concludes with the theological methods of Shiite expansion in Kenya. A descriptive analytical method based on analyzing events, organizing them, and linking each other is used. The research materials were documented and linked it to their original sources. The study ends with a conclusion that includes some recommendations related to the research topic, in addition to the index of references.
Guia de pescado Nordeste Oriental do Brasil
Authors: Barbosa José Milton , Lustosa-Neto Antônio , Carvalho Marina , Santana Thiago , Brabo Marcos , Araújo Ana Rosa , Cintra Israel
Published: March 2022

O Nordeste oriental engloba os estados do Ceará, Rio Grande do Norte, Paraíba, Pernambuco e Alagoas e se refere não apenas à semelhança geográfica da área, mas também às culturais, históricas, humanas e econômicas, além das regiões litorâneas o Nordeste oriental apresenta uma ampla rede de mananciais aquáticos que acumulam grandes volumes d`água. Neste Guia incluímos o estado de Sergipe em função de suas semelhanças geográficas e faunísticas com o Nordeste Oriental. A Região apresenta uma atividade pesqueira intensa, envolvendo muitos pescadores artesanais e uma grande diversidade de espécies, gerando uma atividade comercial de elevada importância econômica, pois também inclui espécies vindas de outra regiões e de outros países. Neste contexto o objetivo do presente guia é discorrer sobre as principais espécies de peixes, camarões e moluscos, comercializadas na região denominada Nordeste Oriental e do estado de Sergipe.
Normalization of Sexuality in Gender Procedures: An Analysis of Language and Gender
Authors: Farhadytooli Morteza
Published: March 2022

Normalization of sexuality in gender procedures, especially the focus on theoretical frameworks of language and gender, is the main concern in this study. This study argues that gender is understood as a social phenomenon and sex as a social material and the main concentration in the research is the investigation into the use of specific frameworks to confirm the idea that there are explicit systems among normalization the sex and gender procedures for either male or female that are affected by the language and gender theories. Indeed, sexual differences are legitimized by the nature of the two-sex system and according to this system normal gender is the social sex of women and men. This is derived from the biological sex. The result of this paper can partly contribute to the language and gender usage areas as well as other academic fields such as sociolinguistics and gender studies.
ÜNİVERSİTE ÖĞRENCİLERİNİN ROMANTİK İLİŞKİLERE YÖNELİK AKILCI OLMAYAN İNANÇLARININ BİLİŞSEL ESNEKLİK DÜZEYLERİ AÇISINDAN İNCELENMESİ
Authors: UYSAL CANTÜRK Pınar
Published: March 2022

Amaç: Bu çalışma üniversite öğrencilerinin romantik ilişkilere yönelik akılcı olmayan inanç düzeyleri ile bilişsel esneklik düzeyleri arasındaki ilişkiyi incelemek amacıyla gerçekleştirilmiştir.

Yöntem: Çalışmaya 203 üniversite öğrencisi katılmıştır. Öğrencilerin 126‘sı kadın (%62,1), 77 ‘si (%37,9) erkektir. Araştırmada veri toplama aracı olarak hazırlanan anket formuyla katılımcılara demografik bilgi formu, Romantik İlişkilerde Akılcı Olmayan İnançlar Ölçeği ve Bilişsel Esneklik Envanteri uygulanmıştır.

Bulgular: Bilişsel esneklik düzeyi ve akılcı olmayan inançların toplam puan ortalamaları arasındaki ilişkiye bakılmış, akılcı olmayan inançlardan “sosyal zaman kullanımı”, “cinsiyet farklılıkları” ve “farklı düşünmek”in bilişsel esneklik azaldıkça arttığı sonucuna varılmıştır. Sınıf düzeyi arttıkça öğrencilerin bilişsel esneklik düzeyleri artmakta ve akılcı olmayan inançlara sahip olmaları azalmaktadır. Ayrıca ilişki yaşama durumuna göre öğrencilerin akılcı olmayan ilişki inançlarına sahip olmaları da farklılaşmaktadır.

Özgünlük: Üniversite öğrencilerinin romantik ilişkilere yönelik akılcı olmayan inançlarını saptamak, ileride kuracakları aile kurumunun işlevselliğine ilişkin bilgi sunabilecektir. Genç yetişkinlerin bilişsel esnekliğini arttırmaya yönelik yapılacak müdahaleler akılcı olmayan inançların ortaya çıkmasını engelleyecek, sağlıklı ve işlevsel ilişkilerin kurulmasına katkıda bulunabilecektir.
Placenta Accreta Spectrum
Authors: Al-Hakeem Aaya Hamid , Meri Marwa Ahmed , Aldujaili Hadeel Haider
Published: March 2022

Histopathological examination of products of conception from miscarriages is part of routine clinical practice. The extent of additional clinically relevant information provided by this investigation in the setting of recurrent spontaneous abortion remains uncertain. The included studies indicated that such examination identify hydatid form moles, villous dysmorphic features suggesting fetal aneuploidy, chronic histiocytic intervillositis (CHI) and massive per villous fibrin deposition and impaired trophoblast invasion. However, in most cases, morphological assessment cannot reliably determine the cause of the miscarriage or distinguish recurrent from sporadic miscarriage. Studies reporting on the use of additional immunohistochemically methods do not currently provide additional clinically useful diagnostic or prognostic information. Routine histological examination of products of conception in the setting of recurrent spontaneous abortion can provide important clinical information in a minority of cases.
İSLAM HUKUKU YASAMA FAALİYETİ BAĞLAMINDA HUKUK-I AİLE KARARNAMESİ’NİN DEĞERLENDİRİLMESİ
Authors: TEPE Süleyman
Published: March 2022

İçerisinde ağırlıklı olarak şer‘i hukuka dair meselelerin yer aldığı Hukuk-ı Aile Kararnamesi İslam Hukuk tarihinde yasama faaliyeti bağlamında çok önemli bir konuma sahiptir. Tanzimat Dönemiyle başlayan kanunlaştırma faaliyetlerinin en önde gelen düzenlemelerinden olan Hukuk-ı Aile Kararnamesi özellikle Hanefi mezhebi dışındaki içtihadi görüşlerin kanunlaştırılması bakımından Osmanlı hukuku yasama faaliyetinde mümtaz bir yerde durmaktadır. Dolayısıyla Hukuk-ı Aile Kararnamesi İslam yasama faaliyeti kuralları çerçevesinde hem hazırlanma usulü hem de içerdiği hükümlerin meşruluğu açısından incelenmesi gereken bir düzenlemedir.

Bu çalışmada Hukuk-ı Aile Kararnamesi gerek İslam ve gerek Osmanlı hukuku yasama faaliyeti açısından değerlendirilmeye çalışılmıştır. Makalenin giriş kısmında; Hukuk-ı Aile Kararnamesinin Osmanlı hukuk müktesebatındaki yeri kısa bir şekilde izah edilmiş akabinde Hukuk-ı Aile Kararnamesinin hazırlanma sebepleri ile muhtevası hakkında bilgiler verilmiştir. Çalışmanın bir sonraki aşamasında ise genel hatlarıyla İslam Hukuku yasama faaliyeti ele alınmıştır. Bu ön bilgilerden sonra Hukuk-ı Aile Kararnamesinin nasıl bir usulle hazırlandığı izah edilmiştir. Akabinde İslam Hukuku yasama faaliyeti bağlamında Kararname incelenmiştir. Bu incelemede bilhassa daha önce Osmanlı hukuk uygulamasında çok sık rastlanmayan Hanefi görüşleri dışındaki hükümlerin “telfik ameliyesi” temelli meşruluk incelemesi üzerinde durulmuştur.
IMPACTO DE LA EMERGENCIA SANITARIA COVID-19 EN LA DECLARACIÓN DE IMPUESTOS DE LOS COMERCIANTES DEL CANTÓN PEDRO CARBO
Authors: Merchan Holguin Ricardo Junior , Lucio Pillasagua Adela del Jesús
Published: March 2022

Las declaraciones de impuestos son parte fundamental para que la Administración Tributaria en la cual se reportan los ingresos percibidos por enajenación de bienes o servicios. El presente trabajo tiene como propósito analizar el impacto de la emergencia sanitaria Covid-19 en la declaración de impuestos de los comerciantes del cantón Pedro Carbo, el cual busca verificar el déficit de los valores tributarios percibidos del periodo 2020, los mercantes se acogieron a las disposiciones dadas por el COE Cantonal, para salvaguardar y mantener controlada la propagación del virus en el cual se vio afectado el ingresos económico, en el cantón Pedro Carbo se vio afectada la actividad comercial en donde el ingreso del consumidor se vio disminuida, Se efectuó metodología descriptiva donde la tabulación de datos es base importante para demostrar y conocer el impacto en la baja de recaudaciones de impuestos, bibliográfico que a través revistas científicas, libros, informes de titulación y normativas vigentes aportando a fomentar esta investigación con bases e información legal, método inductivo permitió elaborar conclusiones de acuerdo las situaciones o sucesos que se hayan desarrollado, a los resultados encontrados se verifico 46% menos de ingresos tributarios, marzo con un 39% menos y septiembre con un 37% de déficit en ingresos de declaraciones que de manera general al año descendió de un 15% menos. En la cual se concluye que este déficit se debe a la emergencia sanitaria durante todo el periodo 2020 y las restricciones tomadas por los entes encargados de regular la emergencia.
Endophytic mycobiota associated to plants of Vaccinium corymbosum L. in Cañete valley- Perú
Authors: Leon Betsabe , Astete Almendra , Mattos Luz , Arévalo Enrique
Published: March 2022

Endophytic fungi (EF) are microorganisms that live asymptomatically within plant tissues. They can confer benefits to the plant as inducers of resistance to pests and diseases, tolerance to abiotic factors, plant growth promoters and mycoparasites of pathogens. This study aimed to isolate, identify, and determine occurrence frequency of endophytic fungi in stems and leaves of blueberry plants collected from ten farms in Lima and Ica Region, Peru. Productive branches of 39 healthy plants were sampled. For the isolation of EF, 702 tissue sections were disinfected and transferred to Petri dishes with potato dextrose agar (PDA) medium, and reproductive structures were induced for identification. A total of 134 EF strains were isolated successfully. Nine genera were identified (Trichoderma, Aspergillus, Alternaria, Ulocladium, Cladosporium, Fusarium, Nigrospora, Lasiodiplodia and Stemphylium). EF occurrence frequency varied greatly between organs, being in leaves more frequent than the stems; likewise, the genera Alternaria and Cladosporium were the most frequent and with most colonized in plant tissues, while Aspergillus, Ulocladium and Lasiodiplodia were the least frequent. These strains could be useful to control plant diseases and, therefore, of great interest in sustainable agriculture.
From Narrative to Reality: The Inter/Trans Discourse of Bakhtin’s Chronotopes and Lyotard’s Metanarratives
Authors: Abdelgawad Naeema
Published: March 2022

Abstract:
Examining the historical and social geography of a nation requires studying the time and the space so as to give rise to a discourse exploring how people interact with each other as well as with their nation. Bakhtin's concept of the chronotope unveils how the inter/trans textual and contextual relationships of narrative time and space intersect with historical moments to generate interactive involvement with certain temporal and geographical scales in the real world. Discussing the chronotopicity of a society is also associated with Jean-Francois Lyotard's concept of metanarratives (aka grand narratives); his ideologies are complementary to Bakhtin's use of the chronotope as an analytical lens; theirs is an inter/trans discourse. The paper seeks to underline the interactive inter/trans discourse between reality and literary narratives from an intertwined Bakhtinian and Lyotardian approach. The article also attempts to accentuate the homogeneity of the concepts of the chronotope and metanarrative because an interactive chronotopic-metanarrative approach facilitates involvement with the reality and makes the oscillation between the fictional and the real possible.
Keywords: Chronotope, narrative, time, space, paralogy
Influencer Marketing in the Digital Age: The Response to Authentic Creator Content
Authors: Jesse P Ong Isaiah , John V Teñoso David , Nicholas G. Valmonte Miguel , E. Etrata, Jr Antonio
Published: March 2022

Abstract
The study aims to determine just how effective influencer marketing is in the digital age, where authenticity and intention can be conflicting factors. With the rapid development in the digital marketing age, the market cannot afford to miss out on a single piece of information considering that it is data that determines the trajectory of businesses. A total of 423 respondents have answered the survey and the data gathered were analyzed using ANOVA and regression. The findings asserted the following: (1) Among the four metrics included in this study, companies tend to choose an influencer/KOL with a good reputation and high credibility over the other influencer metrics, (2) Target customers buy, use, and recommend products of Key Opinion Leaders (KOLs) who have good reputation and high credibility over the other influencer metrics, (3) Target customers buy, accept and recommend products endorsed by influencers over celebrities, (4) Among the influencer/KOL metrics, the target customers prefer reputation and credibility over other metrics, (5) reputation and credibility are significantly associated with influencer marketing, and (6) advertising disclosure, reputation and credibility, and transparency as Key Opinion Leader (KOL) metrics have all positive effect to influencer marketing.
Keywords: authentic creator content, digital age, influencer, influencer marketing
A study of local government strategies to promote youth entrepreneurial clusters in cultural and creative industries
Authors: Hung Chi-Sen
Published: March 2022

2019 was the initial year of Taiwan regional revitalization; the Taiwanese government attempted to solve the issues of overpopulation in big cities due to urbanization, whereas the depopulation issues occur in the rural area. In 2015, the Taichung City Government launched the "Reaching-for-Stars Youth, Dream-Come-True in Taichung"(RSY project), which promotes the establishment of youth entrepreneurial clusters in Taichung City and invites young people of cultural and creative industries to return home for entrepreneurship. In order to investigate the Taichung City Government's strategy for promoting this project, this study adopted grounded theory, in-depth interviews, and field surveys. This study proposes the "Entrepreneurship Base Operation Strategy Framework", which contains five operational strategy facets, the government entrepreneurship policy, local entrepreneurship capital and environmental resources, operation management strategy for incubation and counseling, brand management and marketing of the entrepreneurship base, and local sustainable management.
Exploring Ethical Dilemma in Big Data Analytics: A Literature Review
Authors: Leung Kelvin Tak Yiu , Dembicz Antos , Stevenson Anne
Published: March 2022

Big data analytics has remarkably transformed every sector of the world, including the Emergency Service sector, health sector, science, and space, as well as the business sector, in the way they manage and run their activities every day. Big data analytics has made it possible and easier for all of these sectors to predict future outcomes, make more adequate critical decisions, and take more effective actions respectively. It now gives businesses the power to obtain, access, and leverage customers' data, and even control their behaviors. Many sectors are leveraging big data in that respect, especially businesses. They are incorporating big data analytical tools to obtain their users' data and access their personal information, such as their interests, behavioral pattern, ideas, security details, personal interactions, etc, which they store and leverage for their benefits. This information is obtained and accessed usually without the conscious knowledge and approval of their consumers. This is the major factor that has raised ethical concerns among several leaders and experts about the extent of the personal information that can be accessed, as well as the safety and wellbeing of the common people who are unaware that their personal information is being obtained, accessed, and used. Another concern is about the freedom of individuals. With the innovation and implementation of big data analytics, many of the businesses can technically control their users; what they want, need, and do, and thus, depriving them of the freedom to make decisions on their own. There is also another concern concerning the safety of the intellectual property of individuals and corporations. Big data analytics can lead to intellectual property infringement and theft, thereby denying people and bodies the right to their ideas and innovations.  While on one hand big data analytics yield great promises, on the other hand, it raises critical ethical (security and privacy) issues, which if left unaddressed may become significant barriers to the fulfillment of expected opportunities and long-term success of big data. In this paper, we discuss the ethical dilemmas in big data analytics.
Using Deep Learning in Lyme Disease Diagnosis
Authors: Koduru Tejaswi , Zhang Edward
Published: March 2022

Untreated lyme disease can lead to neurological, cardiac, and dermatological complications. Rapid diagnosis of the erythema migrans (EM) rash, a characteristic symptom of Lyme disease, is therefore crucial to early diagnosis and treatment. In this study, we aim to utilize deep learning frameworks including Tensorflow and Keras to create deep convolutional neural networks (DCNN) to detect images of acute Lyme Disease from images of erythema migrans. This study uses a custom database of erythema migrans images of varying quality to train a DCNN capable of classifying images of EM rashes vs non-EM rashes. Images from publicly available sources were mined to create an initial database. Machine based removal of duplicate images was then performed, followed by a thorough examination of all images by a clinician. The resulting database was combined with images of confounding rashes and regular skin, resulting in a total of 683 images. This database was then used to create a DCNN with an accuracy of 93% when classifying images of rashes as EM vs non EM. Finally, this model was converted into a web and mobile application to allow for rapid diagnosis of EM rashes by both patients and clinicians. This tool could be used for patient prescreening prior to treatment and lead to a lower mortality rate from Lyme disease.
The Role of Geography in Shaping a Polis
Authors: Le Wei , Duhamel Patrick , Rajkotwalla Munira
Published: March 2022

The comparison between Athens and Sparta has dominated the study of classical Greek civilisations for a long period of time. While much of the existing literature focuses on the political, social and economic differences between Greek city states, it fails to ask why these differences exist. This paper combines an existing wealth of literature on Greek geography with literature on the ancient Greek polises to analyse the role of geography in shaping a civilisation. It begins by decoding geography as an environmental stressor and then shows its political, economic and social outcomes in Athens and Sparta respectively. The above comparison suggests that the human responses to geography as an environmental stressor are crucial to whether and how a political community exists.
On the Collection and Use of Fish Scales for Fisheries Management: Pros, Cons, and Potential Solutions
Authors: Wahlig Patrick , Sommer Nathalie
Published: March 2022

Fisheries have enormous ecological and economic importance to the planet, yet threats of overfishing and climate change are altering the structure of the world’s fisheries. In order to assess and properly manage fisheries, information including fish age, size, growth rate, and origin must be gathered. Various fish body structures can yield this data but acquiring such information requires lethal sampling and arduous analysis techniques. Fish scales, however, do not present such limitations, as scales are ubiquitous, can be sampled nonlethally, and are inexpensive to analyze. Fish scales have known drawbacks which have stymied full adoption by fisheries management. Current issues with scales are discussed, specifically scale resorption and regeneration, and practical solutions to these issues are proposed. While scales have a long history of utility in fisheries management, their potential for wider application remains enormous. The synthesized information and suggested studies in this review offer a path forward for scale analysis to become more efficient and accurate, thereby eliminating lethal sampling methods while improving fisheries management.
Two Perspectives on Implementation of Carbon Tax Tackling Climate Change: A Literature review
Authors: Kim Elliot , Sher Allen
Published: March 2022

The international community has been continuously discussing carbon tax as a means to tackle climate change. In July 2021 came the announcement of the European Union's Carbon Border Adjustment Mechanism (CBAM). Many countries have expressed their concerns over its impact on their economies. This article reviews a total of ten articles, including eight journal papers, one policy paper and one news article, related to the implementation of carbon tax. Two distinct perspectives over carbon tax can be discerned from this literature review. One sees that the introduction of carbon taxes can help to mitigate climate change. Another sees it leading to negative economic ripple effects, acting as a new kind of tax-free barrier. The CBAM policy itself is still just beginning to be implemented, so no one is sure how the outcome of its implementation will affect each country's economic structure. Neither is it clear how to do a detailed estimation without first knowing to what extent implementation of carbon tax would harm economic structure within developing countries, as well as the potential countermeasures and responses of each country. This review hopes to contribute to further studies in order to better understand the impact of carbon tax and carbon emissions reduction, in consideration of each country's economic structure and feature, can help countries prepare for its implementation.