bluuebunny/crossref_metadata_2025 huggingface dataset:
O TRABALHO DE MULHERES JORNALISTAS DURANTE A PANDEMIA DA COVID-19
Authors: Solon Marina , Araújo Mayara , Rodrigues Naiana , Vidal Nunes Márcia
Published: March 2021

Este artigo traz reflexões sobre o trabalho de mulheres jornalistas no Ceará durante a pandemia de Covid-19. Com o isolamento social imposto pelo governo do Estado como uma das ações de combate à pandemia, mulheres tiveram que adequar atividades profissionais ao espaço da casa, dividindo a força de trabalho entre a profissão, as tarefas domésticas e o cuidado com a família (BIROLI, 2018; FEDERICI, 2019; HUWS, 2014). Para observar esse cenário, este estudo de caso exploratório (YIN, 2001) se vale de dados  obtidos  pela pesquisa nacional “Como trabalham os comunicadores em tempos de pandemia da Covid-19”, realizada pelo Centro de Pesquisa em Comunicação e Trabalho (CPCT-ECA-USP); e de informações procedentes de entrevistas semi-estruturadas com oito jornalistas cearenses . Os resultados apontam que os regimes de home office e rodízio redação-casa, adotados durante a pandemia, aprofundam o cenário já consolidado de precarização do trabalho jornalístico  (FÍGARO, 2013; MICK; LIMA, 2013;) e do trabalho de mulheres jornalistas, especificamente (FIGARO, 2018; LELO, 2019;); e geram intensificação do ritmo de trabalho, maior cobrança por produtividade e desgaste psicológico/emocional das profissionais; além de evidenciarem uma divisão sexual do trabalho ainda prevalente, porém seletiva.
CUIDADO, BRANQUITUDE E INTERDEPENDÊNCIA
Authors: Dalbosco Dell'Aglio Daniela , Machado Paula Sandrine
Published: March 2021

Esse artigo parte de reflexões e análises durante o período de isolamento social devido à pandemia da Covid-19 de forma a pensar como que o cuidado é atuado nesse período onde as mulheres se veem no contexto do “trabalhar em casa”. Julga-se necessário falar da especificidade da branquitude de maneira a desnaturalizar a neutralidade do ser mulher, pontuando que enxergar esse fenômeno apenas por uma ótica da “divisão sexual do trabalho” invisibiliza as relações de opressão e privilégios que faz uma rede de cuidados ser possível. Articulamos com o conceito de interdependência, para refletir que para o sistema se manter e o cuidado acontecer, tarefas tendem a ser delegadas, eximindo-se de responsabilidades mesmo em contextos de pandemia. Concluímos que é mais que necessário reorganizar redes de modo que a responsabilidade coletiva exista no cotidiano para além dos tempos de crise.
O COVID -19 NO TERRITÓRIO DAS MULHERES PREFEITAS
Authors: Brasileiro Cyntia , Albuquerque Terezinha , Borborema José Silvan
Published: March 2021

Este artigo objetiva discutir sobre a incidência do novo coronavírus na gestão das mulheres prefeitas do Nordeste do Brasil, na pespectiva  de traçar um panomara sobre como a pandemia se apresenta nestas gestões. Trabalhos de Brollo & Troiano (2012) e Grossi & Miguel (2001);  apontam para o desempenho das mulheres enquanto gestoras, principalmente na área da saúde pública, o que nos faz questionar: As gestoras municipais brasileiras conseguiram, em suas estratégias, diminuir o número de contágio e morte? Neste sentido, buscamos introduzir uma discussão a respeito das mulheres em cargos públicos (CARVALHO & YASUDA, 2017, DAHLERUP&FREINDEVALL, 2010; PRÁ, 2013; VIOTTI, 1995) e, a partir disso (1) Mapear o panorama nordestino, destacando onde há incidência de casos em gestão de prefeitas; (2) Identificar estados com maior predomínio no número de casos com óbitos nos municípios gestados por mulheres (3) Destacar o município onde ocorre a maior incidência do Covid-19. Trata-se de uma pesquisa exploratória e quantitativa, cujas metodologias para a produção foram: dados do Covid-19 retirados dos boletins diários do Ministério da Saúde, casos confirmados e mortes nos municípios nordestinos até 17 de Maio, avaliando dois meses depois do primeiro óbito. Com a tabulação e cruzamento de dados, podemos visualizar que a incidência de casos e mortes no recorte proposto são relativamente baixos. A pesquisa se justifica visando compreender fenômenos que são particulares e que geram impactos sociais, assim como defender a inclusão de mais mulheres em cargos de chefia na política.
Genetic Diversity of Omani Durum Wheat (Triticum turgidum sub sp. durum) Landraces
Authors: Al Lawati Ali H. , Nadaf Saleem K , AlSaady Nadiya A. , Al Hinai Saleh A. , Almamari Almandhar , Al Adawi Masoud H. , Al Hinai Rashid S. , Al Maawali Abdulaziz
Published: March 2021

Introduction:

The Sultanate of Oman is rich in diversity of the most important crops like wheat, which not only has a global significance but is also regarded as one of the strategic crops in the country. The country has an ancient cultivation history of both bread wheat (Triticum aestivumL.s.l.) and durum wheat (Triticum turgidumsub sp.durum) because of its characteristic location on the eastern edge of the Arabian Peninsula. Wheat landraces constitute the prime genetic resources of cultivated wheat not only in Oman but also in several MENA (the Middle East and North Africa) countries. Indigenous landraces have paramount significance for their potential utilization in crop improvement and conservation programs. Hence, the present study was undertaken to subject 17 indigenous durum wheat accessions for analyses of diversity to select parents for hybridization in national crop improvement programs.

Materials and Methods:

The trial was conducted consecutively for two cropping seasons (2017-2018 and 2018-2019) during winter from November to March on the layouts of a loamy soil site under sprinkler irrigation system in Augmented Design with five check varieties replicated five times randomized and distributed throughout the experimental area under spacing and crop husbandry practices as per national recommendations. The data on 9 quantitative (Plant descriptors) and 6 qualitative traits on the presence (score 1) or absence (score 0) of pigmentation on 6 plant parts were collected. These traits were subjected to both Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) to comprehend the contribution of these characters towards diversity and form prime diverse clusters from 17 indigenous durum wheat landraces to select appropriate parents for crossing.

Results:

The results indicated that indigenous durum wheat accessions were significantly different (p>0.05) with respect to all the quantitative characters except the number of tillers. Of 36 combinations of associations among 9 agro-morphological characters’ studied, only six correlations involving four charactersviz. tiller no., spikelets/ spike, grains/spike, and grain length were found significant (p<0.05). The results of two multivariate analyses indicated the formation of four diverse clusters with different compositions of accessions, thus not supporting each other in discerning diversity. The parents were selected for hybridization for improving characters of growth for higher yield or productivity with one or two identifying markers of pigmentation on plant parts.

Conclusion:

The indigenous durum wheat landraces / accessions were found to be more diverse and potential for use in the national crop improvement programs for higher productivity.
Effectiveness of next generation science standards based 5e learning model by utilizing local potential
Authors: Rahmita Rahmita , Rosana Dadan
Published: March 2021

This study aims at revealing the effectiveness of the next generation science standards based 5E learning model by utilizing the local potential of environmental education centre Puntondo to enhance students’ data literacy and problem-solving abilities. This research can be categorized as an experimental study. The subjects of this study were the seventh grade students of State Junior High School 2 Takalar. Two classes were involved, totaling 64 students. The data collection technique was carried out by using the test instrument. The data analysis technique used the gain score test and t-test analysis. The results showed that the gain score for the two classes for both abilities was in the medium category, with a value indicating that the gain from the experimental class was greater than the control class. Meanwhile, the t-test value is Sig. (2.tailed) data literacy of 0.003 and problem solving of 0.008. The acquisition of the value of the two abilities shows that the Sig. (2.tailed) is less than 0.05. Based on the research results, it can be concluded that the NGSS-based 5E learning model by utilizing the local potential of EEC Puntondo is considered effective to enhance the data literacy and problem-solving abilities.
Improving Medication Adherence Through Adaptive Digital Interventions (iMedA) in Patients With Hypertension: Protocol for an Interrupted Time Series Study
Authors: Etminani Kobra , Göransson Carina , Galozy Alexander , Norell Pejner Margaretha , Nowaczyk Sławomir
Published: March 2021

Background

There is a strong need to improve medication adherence (MA) for individuals with hypertension in order to reduce long-term hospitalization costs. We believe this can be achieved through an artificial intelligence agent that helps the patient in understanding key individual adherence risk factors and designing an appropriate intervention plan. The incidence of hypertension in Sweden is estimated at approximately 27%. Although blood pressure control has increased in Sweden, barely half of the treated patients achieved adequate blood pressure levels. It is a major risk factor for coronary heart disease and stroke as well as heart failure. MA is a key factor for good clinical outcomes in persons with hypertension.

Objective

The overall aim of this study is to design, develop, test, and evaluate an adaptive digital intervention called iMedA, delivered via a mobile app to improve MA, self-care management, and blood pressure control for persons with hypertension.

Methods

The study design is an interrupted time series. We will collect data on a daily basis, 14 days before, during 6 months of delivering digital interventions through the mobile app, and 14 days after. The effect will be analyzed using segmented regression analysis. The participants will be recruited in Region Halland, Sweden. The design of the digital interventions follows the just-in-time adaptive intervention framework. The primary (distal) outcome is MA, and the secondary outcome is blood pressure. The design of the digital intervention is developed based on a needs assessment process including a systematic review, focus group interviews, and a pilot study, before conducting the longitudinal interrupted time series study.

Results

The focus groups of persons with hypertension have been conducted to perform the needs assessment in a Swedish context. The design and development of digital interventions are in progress, and the interventions are planned to be ready in November 2020. Then, the 2-week pilot study for usability evaluation will start, and the interrupted time series study, which we plan to start in February 2021, will follow it.

Conclusions

We hypothesize that iMedA will improve medication adherence and self-care management. This study could illustrate how self-care management tools can be an additional (digital) treatment support to a clinical one without increasing burden on health care staff.

Trial Registration

ClinicalTrials.gov NCT04413500; https://clinicaltrials.gov/ct2/show/NCT04413500

International Registered Report Identifier (IRRID)

DERR1-10.2196/24494
Risk Factors of Cholera Transmission in Al Hudaydah, Yemen: Case-Control Study
Authors: Qaserah Abdulqawi Mohammed , Al Amad Mohammed Abdullah , Al Serouri Abdulwahed Abduljabbar , Khader Yousef Saleh
Published: March 2021

Background

Yemen has recently faced the largest cholera outbreak in the world, which started at the end of 2016. By the end of 2017, the cumulative reported cases from all governorates reached 777,229 with 2134 deaths. Al Hudaydah was one of the most strongly affected areas, with 88,741 (18%) cases and 244 (12%) deaths reported.

Objective

The aim of this study was to determine the risk factors associated with cholera transmission in Al Hudaydah city, Yemen.

Methods

From December 1, 2017 to January 10, 2018, a total of 104 patients with cholera (57 women and 47 men) who presented at cholera treatment centers in Al Hudaydah city with three or more watery stools in a 24-hour period and with moderate or severe dehydration were identified for inclusion in this study. Each case was matched by age and gender with two controls who were living in the neighboring house. A semistructured questionnaire was used to collect data on behavioral and environmental risk factors such as drinking water from public wells, storing water in containers, consumption of unwashed vegetables or fruits, and sharing a toilet.

Results

The median age of the cases and controls was 20 years (range 5-80) and 23 years (range 5-85), respectively. Only 6% of cases and 4% of controls were employed. Multivariate analysis showed that eating unwashed vegetables or fruits (odds ratio [OR] 7.0, 95% CI 1.6-30.6, P=.01), storing water in containers (OR 3.0, 95% CI 1.3-7.3, P=.01), drinking water from a public well (OR 2.5, 95% CI 1.1-5.7, P=.02), and using a public toilet (OR 5.2, 95% CI 1.1-24.4, P=.04) were significantly associated with cholera infection risk.

Conclusions

The cholera transmission risk factors in Al Hudaydah city were related to water and sanitation hygiene. Therefore, increasing awareness of the population on the importance of water chlorination, and washing fruits and vegetables through a health education campaign is strongly recommended.
Peer Review of “A Framework for a Statistical Characterization of Epidemic Cycles: COVID-19 Case Study” (Preprint)
Authors: Salman Mo
Published: March 2021

UNSTRUCTURED

This is a peer review report.
Finding Relevant Psychoeducation Content for Adolescents Experiencing Symptoms of Depression: Content Analysis of User-Generated Online Texts (Preprint)
Authors: Dysthe Kim K , Haavet Ole R , Røssberg Jan I , Brandtzaeg Petter B , Følstad Asbjørn , Klovning Atle
Published: March 2021

BACKGROUND

Symptoms of depression are frequent in youth and may develop into more severe mood disorders, suggesting interventions should take place during adolescence. However, young people tend not to share mental problems with friends, family, caregivers, or professionals. Many receive misleading information when searching the internet. Among several attempts to create mental health services for adolescents, technological information platforms based on psychoeducation show promising results. Such development rests on established theories and therapeutic models. To fulfill the therapeutic potential of psychoeducation in health technologies, we lack data-driven research on young peoples’ demand for information about depression.

OBJECTIVE

Our objective is to gain knowledge about what information is relevant to adolescents with symptoms of depression. From this knowledge, we can develop a population-specific psychoeducation for use in different technology platforms.

METHODS

We conducted a qualitative, constructivist-oriented content analysis of questions submitted by adolescents aged 16-20 years to an online public information service. A sample of 100 posts containing questions on depression were randomly selected from a total of 870. For analysis, we developed an a priori codebook from the main information topics of existing psychoeducational programs on youth depression. The distribution of topic prevalence in the total volume of posts containing questions on depression was calculated.

RESULTS

With a 95% confidence level and a ±9.2% margin of error, the distribution analysis revealed the following categories to be the most prevalent among adolescents seeking advice about depression: self-management (33%, 61/180), etiology (20%, 36/180), and therapy (20%, 36/180). Self-management concerned subcategories on coping in general and how to open to friends, family, and caregivers. The therapy topic concerned therapy options, prognosis, where to seek help, and how to open up to a professional. We also found young people dichotomizing therapy and self-management as opposite entities. The etiology topic concerned stressors and risk factors. The diagnosis category was less frequently referred to (9%, 17/180).

CONCLUSIONS

Self-management, etiology, and therapy are the most prevalent categories among adolescents seeking advice about depression. Young people also dichotomize therapy and self-management as opposite entities. Future research should focus on measures to promote self-management, measures to stimulate expectations of self-efficacy, information about etiology, and information about diagnosis to improve self-monitoring skills, enhancing relapse prevention.
The Effect of Digital Health Interventions on Parents’ Mental Health Literacy and Help Seeking for Their Child’s Mental Health Problem: Systematic Review (Preprint)
Authors: Peyton Daniel , Goods Marquelle , Hiscock Harriet
Published: March 2021

BACKGROUND

Many children with mental health problems do not receive professional help. Despite the frequent use of digital health interventions (DHIs) such as websites or web-based service navigation platforms, their effects on parents’ mental health literacy, help seeking, or uptake of professional services are unclear.

OBJECTIVE

This study aims to provide a systematic review and narrative synthesis to describe whether DHIs improve the aforementioned parental outcomes.

METHODS

Databases, including CINAHL, Embase, MEDLINE OVID, PsycINFO, and PubMed (2000-2020), were accessed. Studies were included if they evaluated quantitative changes in mental health literacy, help seeking, or the uptake of services by parents of children with mental health problems. Theoretical frameworks, sample sizes, participant demographics, recruitment, interventions, DHI use, results, and health economic measures were used for data extraction.

RESULTS

Of the 11,379 search results, 5 (0.04%) studies met the inclusion criteria. One randomized controlled trial found the reduced uptake of services after using a DHI coupled with a telephone coach for a child’s behavioral problem. Of 3 studies, 2 (66.7%) found statistically significant improvement in mental health literacy for attention-deficit/hyperactivity disorder but had no control group. One study found nonsignificant improvement in mental health literacy and help-seeking attitudes toward anxiety and depression compared with those in active controls. All studies were rated as having a high or serious risk of bias. Search results were affected because of a single reviewer screening articles, overall low-quality studies, and a lack of consistent nomenclature.

CONCLUSIONS

There is no high-quality evidence that DHIs can improve parents’ mental health literacy, help seeking, or uptake of services. More research is needed to evaluate DHIs by using rigorous study designs and consistent measures.

CLINICALTRIAL

PROSPERO International Prospective Register of Systematic Reviews CRD42020130074; https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020130074
Patient Portals to Support Palliative and End-of-Life Care: Scoping Review (Preprint)
Authors: Ingle M Pilar , Valdovinos Cristina , Ford Kelsey L , Zhou Shou , Bull Sheana , Gornail Starlynne , Zhang Xuhong , Moore Susan , Portz Jennifer
Published: March 2021

BACKGROUND

Although patient portals are widely used for health promotion, little is known about the use of palliative care and end-of-life (PCEOL) portal tools available for patients and caregivers.

OBJECTIVE

This study aims to identify and assess the user perspectives of PCEOL portal tools available to patients and caregivers described and evaluated in the literature.

METHODS

We performed a scoping review of the academic literature directed by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) extension for Scoping Review and searched three databases. Sources were included if they reported the development or testing of a feature, resource, tool, or intervention; focused on at least one PCEOL domain defined by the National Coalition for Hospice and Palliative Care; targeted adults with serious illness or caregivers; and were offered via a patient portal tethered to an electronic medical record. We independently screened the titles and abstracts (n=796) for eligibility. Full-text (84/796, 10.6%) sources were reviewed. We abstracted descriptions of the portal tool name, content, targeted population, and reported user acceptability for each tool from included sources (n=19).

RESULTS

In total, 19 articles describing 12 tools were included, addressing the following PCEOL domains: ethical or legal (n=5), physical (n=5), and psychological or psychiatric (n=2). No tools for bereavement or hospice care were identified. Studies have reported high acceptability of tools among users; however, few sources commented on usability among older adults.

CONCLUSIONS

PCEOL patient portal tools are understudied. As medical care increasingly moves toward virtual platforms, future research should investigate the usability and acceptability of PCEOL patient portal resources and evaluate their impact on health outcomes.

CLINICALTRIAL
Coarse-Grained Sentiment Analysis Berbasis Natural Language Processing – Ulasan Hotel
Authors: Warnia Nengsih  , M. Mahrus Zein  , Nazifa Hayati
Published: March 2021

Sentiment analysis adalah metode untuk memperoleh data dari berbagai platform yang tersedia di internet. Kemajuan teknologi memungkinkan mesin untuk mengenali suatu istilah yang dianggap sebagai opini positif maupun sebaliknya. Data-data dan opini tersebut berperan penting sebagai umpan balik produk, layanan, dan topik lainnya. Tanpa perlu memperoleh opini secara langsung dari masyarakat, pihak penyedia telah mendapatkan evaluasi yang penting guna mengembangkan diri. Bisnis perhotelan merupakan bidang yang terkait dengan jasa memberikan layanan pada pelanggan. Indikator keberlangsungan bisnis ini juga bergantung pada umpan balik pelanggannya dan dijadikan sebagai acuan untuk pengambilan kebijakan strategis. Teknik sentiment analysis berbasis Natural Language Processing dapat mengatasi permasalahan tersebut. Pada makalah ini prediksi dilakukan menggunakan classifier Random Forest (RF), sementara untuk merangkum kualitas classifier, digunakan kurva Receiver Operating Characteristic (ROC). Kurva ROC berupa grafik yang baik untuk merangkum kualitas classifier. Semakin tinggi kurva berada di atas garis diagonal, semakin baik prediksinya, dengan nilai kurva ROC yang diperoleh sebesar 0,90. Terlihat hasil ulasan terhadap opini pelanggan terhadap jasa dan pelayanan yang diberikan oleh hotel untuk kategori positif lebih banyak daripada kategori negatif. Polaritas dari ulasan diperoleh 68% ulasan pelanggan berada pada area positif dan 32% berada pada area negatif.
IN VITRO ANTIOXIDANT AND IN VIVO ANTIDIABETIC ACTIVITY OF TWO POTENTIAL PROBIOTIC ENTEROCOCCUS SPP. ON ALLOXAN-INDUCED DIABETIC RATS
Authors: RAJPUT KAMNI , CHANDRA DUBEY RAMESH
Published: March 2021

Objective: In vitro antioxidant activity, in vivo antidiabetic property and intestinal attachment by two potential probiotic bacterial strains, namely, Enterococcus faecium and Enterococcus hirae were studied using albino rats.

Methods: Antioxidant the activity was assessed using 2,2-Diphenyl-1-picrylhydrazyl radicals scavenging assay. Alloxan was administered intraperitoneally to induce diabetic conditions in experimental rats. Animals were treated with oral administration of Enterococcus spp., such as E. faecium, and E. hirae isolated from goat and sheep milk. The control animal group received normal saline for the same days. Glibenclamide drug was used as a positive control against probiotic bacterial cells.

Results: However, administration of probiotic bacterial strains E. faecium and E. hirae, in albino rats significantly (p<0.05) at varying doses lowered blood glucose levels in diabetic rats as compared to the diabetic control group. Both the species of Enterococcus increased the bodyweight of experimental rats. However, E. faecium was the best antidiabetic strain having the antioxidant activities also in comparison to E. hirae. The attachment of probiotic bacterial cells E. faecium on the rat’s intestine wall against pathogens was examined. Furthermore, E. faecium showed its aggregation with pathogens by attachment of the intestines of albino rats. This showed that both the bacterial strains exhibited in vivo antidiabetic effect.

Conclusion: The results of this study showed that probiotic bacteria possess antioxidant, antidiabetic activities, and attachment of intestine.
BIOMARKERS IDENTIFICATION AND THERAPY TARGET IN MACROPHAGE OF ATHEROSCLEROSIS: SYSTEMATIC REVIEW
Authors: KURNIATI NENG FISHERI , MUHAMMAD HUBBI NASHRULLAH , PRASESTI GAYUK KALIH
Published: March 2021

Macrophages are known to play an important role in the initiation and progression of atherosclerosis; however, the molecular signaling pathways in macrophages that are responsible for plaque rupture have not been fully identified. This study aims to identify biomarkers and therapy targets in macrophages in atherosclerotic conditions by systematic review. Research procedure of systematic reviews using the PRISMA protocol. The search engine used in this study is PubMed, with the keywords ([macrophage] AND atherosclerosis) AND (signaling pathway OR signaling pathway), the reference application used is Zotero to screen clinical articles. There were 689 articles identified and 11 clinical articles in inclusion criteria were obtained. The identification resulted in 30 biomarkers associated with macrophages in atherosclerotic conditions. The proposed biomarkers of atherosclerosis are interleukin (IL)-1β and IL-18. The proposed potential therapy targets for atherosclerosis are LOX-1 and schematic images of biomarkers in atherosclerotic plaques.
ANTIFUNGAL ACTIVITY OF ACTINOBACTERIA WITH A POTENTIAL TO INHIBIT RICE BLAST FUNGUS MAGNAPORTHE ORYZAE (ANAMORPH PYRICULARIA ORYZAE)
Authors: R THILAGAM , R BALAGURUNATHAN , M SANGEETHA , N HEMALATHA
Published: March 2021

Objective: The aims of the present study were to screen the actinobacteria with high potential ability to produce secondary metabolites that have inhibitory activity against plant pathogenic fungi, Magnaporthe oryzae. Production of secondary metabolites was analysis by thin-layer chromatography and bioautography assay.

Methods: Screening and selection of potential Streptomyces sp. morphological, cultural, physiological, and biochemical characterization of the screened isolate was carried out. Antifungal compound was confirmed by bioautography assay.

Results: Bioautography method use in this study was found to be antifungal fraction from the crude extract. Antifungal secondary metabolites can be readily located on the plates by observing clear zones where active compounds inhibit fungal growth.

Conclusion: The bioautography assay shows that this isolates can produce antifungal compound. Therefore, this isolate proves to be a promising microbe which can be further studied for its applications a biocontrol agent against rice blast fungi.
DRUG-RELATED PROBLEMS AND ITS PRESCRIBING INDICATORS IN STROKE PATIENTS: A PROSPECTIVE OBSERVATIONAL STUDY
Authors: THAMMISETTY DURGA PRASAD , RANGANAYAKULU DIVITI , NAYAKANTI DEVANNA
Published: March 2021

Objective: The objective of the study was to assess the drug-related problems (DRPs) and the World Health Organization (WHO) core prescribing indicators among stroke patients.

Methods: A prospective observational study was conducted among stroke inpatients of Acute Medical Care and General Medicine Department of a tertiary care hospital located in Tirupati, Andhra Pradesh, India. A suitable data collection form was used to collect the data about demographics, clinical characteristics, WHO prescribing indicators, and DRPs. Descriptive statistics were used to represent the demographics, distribution of DRPs, and prescribing indicators in the study. Chi-square test was employed to test the significant association between the demographics and the occurrence of DRPs.

Results: Among 174 patients included in the study, 89 had one or more DRPs. A total of 122 DRPs were identified in the study population. Drug interactions (48.4%) and adverse drug reactions (ADRs) (17.2%) were commonly observed DRPs. A significant direct association was observed between the occurrence of DRPs and number of comorbidities (p<0.001), polypharmacy (p<0.001), and hospital stay (p<0.05). The average number of drugs per prescription was 7.2. Of drugs prescribed, 67.6% were in their generic names. The percentage of encounters in which an antibiotic, injection was prescribed was 65.5% and 89.6% respectively. The percentage of drugs prescribed from an essential drug list was 91.2%.

Conclusion: The rate of drug interactions and ADRs was high in treatment of stroke patients. Patients suffering from comorbidities, polypharmacy, and long hospital stay were positively associated with occurrence of DRPs in stroke. Regular monitoring and screening for drug interactions and ADRs were advised to reduce the burden DRPs in stroke patients admitted in a critical care unit.
Applications of measure of noncompactness for the solvability of an infinite system of second order differential equations in some integrated sequence spaces
Authors: Das Rituparna , Sapkota Niraj
Published: March 2021

The aim of this paper is to study the infinite system of second order differential equations along with the given boundary conditions for its solvability in some integrated sequence spaces. The result is achieved with the analytical tool namely the measure of noncompactness along with the idea of Meir-Keeler condensing operator and provides the realization of the sufficient conditions for the existence results in these Banach Sequence spaces. We also illustrate the results with examples.
Determinant Factors of Supervisor Model 4S (Structure, Skill, Support, Sustainability) Against the Implementation of Islamic Spiritual Care
Authors: Dewi Inggriane Puspita , Mustikaningsih Dewi
Published: March 2021

Introduction: The supervision model commonly applied in nursing is the 4S model, namely the Structure, Skill, Support and Sustainability (4S) stages. This supervision model can be applied by the head of the room and the head of the shift as a supervisor in overseeing the implementation of Islamic spiritual nursing care in adult inpatient rooms. Purpose: to analyze the relationship between the role of the 4S supervisor model and the implementation of Islamic spiritual nursing care in adult inpatient rooms. Methods: the study used a cross sectional method. The sampling technique with a proportionate stratified random sampling was 62 nurses. Data analysis used univariate, bivariate analysis with Spearman test, and multivariate with logistic regression. Results: showed the role of the 4S supervisor model was good (88.7%), the implementation of Islamic nursing care was good category (52%), there was a relationship between the role of model supervision 4S with the implementation of Islamic spiritual care, with a significance value of <0.0001 and the strongest relationship between the 4S model and the implementation of Islamic spiritual care is the variable skill and sustainability, seen from the significance value for skills of 0.05 (Pvalue ≤0.05), and sustainability of 0.01 (Pvalue ≤0.05). The strength of the relationship is seen based on the OR [EXP {B}] value, respectively, skill (0.194) and sustainability (0.109). Discussion: The probability of nurses implementing Islamic nursing care well is 90% if they provide Islamic spiritual nursing care skills and continuous supervision by the hospital supervisor.
Family Medicine Resident Knowledge of Adverse Childhood Experiences
Authors: Collins Kimberly , Spice Carolin , Ingraham Bailey C. , Al Achkar Morhaf
Published: March 2021

Introduction: Exposure to adverse childhood experiences (ACEs) has been associated with poor health in adulthood. Primary care providers can provide more appropriate medical care and intervene if they ask patients about ACEs. The purpose of this study is to determine existing knowledge and attitudes about ACEs among family medicine residents within the Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI) region.
Methods: Researchers developed a nine-question survey to assess family medicine residents’ knowledge and attitudes about ACEs, and their comfort level in addressing ACEs. The survey was distributed to 540 residents in 22 family medicine residency programs in the WWAMI region.
Results: Most residents reported they had some (32%) or moderate (35%) knowledge of the ACEs study. However, 30% reported no knowledge of the ACEs study, and very few (3%) reported significant knowledge. Of 117 respondents reporting at least some prior knowledge of ACEs, 42% had first heard about ACEs during residency. The ACEs topics that respondents felt least comfortable addressing during a patient encounter were a patient’s personal history of sexual abuse (75%) and witnessing physical abuse (47%). Most residents (84%) indicated that they would like to see ACEs integrated into their residency curriculum.
Discussion: This study demonstrates a gap in residency training on the topic of ACEs in family medicine residencies within the WWAMI region. Residents are uncomfortable addressing ACEs with patients but are receptive to learning about this topic. More teaching about ACEs can increase residents’ comfort level with addressing these topics in the primary care setting.
Imunidades em tempos de crise fiscal
Authors: Vasconcelos Pedro
Published: March 2021

Diante da atual crise fiscal, passou-se a discutir no Congresso Nacional se a imunidade tributária das entidades beneficentes de assistência social deveria ser suprimida com a finalidade de aumentar a arrecadação estatal e sanear o combalido e deficitário orçamento público. O objetivo do presente artigo é analisar se a imunidade tributária do chamado “terceiro setor” prevista no art. 195, § 7º, da Constituição é justificável sob uma ótica jurídico-econômica. O estudo, do tipo descritivo-analítico, é realizado por meio de pesquisa documental, à luz da doutrina, da jurisprudência e de dados produzidos por entidades públicas e privadas. Ao final, conclui-se pela necessidade de manutenção da imunidade conferida ao terceiro setor.
O monstro da sexualidade infantil: a resposta penal mais adequada ao pedófilo
Authors: Ulisses Layssa Franco Jacob
Published: March 2021

O presente artigo versa sobre os aspectos jurídicos e psicológicos da ação do pedo?filo. Para evitar equívocos relacionados a inúmeras perspectivas disseminadas no senso comum durante os anos, o contexto histórico da pedofilia e a errônea utilização do termo serão averiguados, pois são diversos aqueles que caracterizam todo e qualquer crime sexual contra crianças como crime de pedofilia. Nesse sentido, os objetivos deste artigo são: analisar a resposta penal mais adequada ao pedo?filo e o enquadramento da pedofilia no ordenamento jurídico brasileiro; abordar a aplicação de tratamentos apropriados e eficazes para conter os impulsos sexuais do portador de transtorno pedofílico, para possibilitar-lhe a ressocialização e evitar reincidências. Para tanto, o presente estudo realizou pesquisas bibliográficas qualitativas no ramo do Direito Penal, voltado aos crimes sexuais contra crianças. Foram adotados métodos de abordagens dedutivas, levantamentos e estudos bem como dados e informações que almejam entender as particularidades do pedófilo, com o objetivo de estudar o controle social. Compreende-se que a pedofilia não abrange somente o desejo sexual por um menor de idade, mas também se caracteriza como um transtorno psicológico que, caso não tratado, estimulará o agente a reincidir.
Pode o fisco ajuizar ação para rever decisão administrativa favorável ao contribuinte?
Authors: Sorrentino Thiago B
Published: March 2021

Em 2020, o Congresso Nacional modificou a legislação federal para tornar inaplicável o voto de qualidade. Com a inaplicabilidade, os julgamentos que terminassem empatados na seara tributária passariam a ser decididos favoravelmente ao sujeito passivo. Com o aparente fim do voto de qualidade, começou-se a especular o ajuizamento de ações com o objetivo de anular tais decisões. Assim, este artigo aborda a questão pela aproximação de duas espécies de legitimidade: processual e republicana. Por fim, conclui que o Estado somente tem legitimidade para anular decisões administrativas definitivas favoráveis aos sujeitos passivos se houver grave erro de procedimento, como a corrupção ou a venalidade dos julgadores.
Breve comparativo entre o juiz da investigação (Alemanha) e o juiz "das garantias" (Brasil)
Authors: Tavernard Lima Fernando Antônio
Published: March 2021

O artigo apresenta uma análise, a título de direito comparado, entre o Ermittlungsrichter (juiz da investigação) do Código de Processo Penal alemão e o “juiz das garantias”, introduzido no Código de Processo Penal brasileiro (CPP) pela Lei Federal 13.964/2019. O principal propósito é examinar a repartição da competência penal originária, em nível de primeira instância, concomitantemente à competência recursal, e da competência funcional desses juízes nos respectivos sistemas processuais (Alemanha e Brasil). Para tanto, pautar-se-á pelo método de abordagem expositivo-qualitativa desses institutos jurídicos, embasado na literatura sobre a competência, o que, no restrito plano sistemáticonormativo, permitirá detectar as particularidades de cada um. Na conclusão, sustenta-se que a funcionalidade do juiz “das garantias” pode não surtir o benefício jurídico almejado, dada a extensão da competência que lhe fora outorgada dentro da complexidade de nossa estrutura judiciária.
Permanent pacemaker implantation in a hemodialysis patient with subclavian vein occlusion using the balloon-target puncture technique
Authors: Kasai Yuhei , Shakya Sandeep , Yamaura Takashi , Hayakawa Naoki , Miyaji Kotaro , Kanda Junji
Published: March 2021

We describe a case of permanent pacemaker implantation in a 59-year-old
male with subclavian vein occlusion undergoing hemodialysis. The
balloon-target puncture technique aided successful and safe transvenous
permanent pacemaker implantation.
Cerebral Venous Thrombosis with Skull Base Osteomyelitis and a Retropharyngeal Mass
Authors: Oommen Jerry , Valiuddin Hisham , Ring Hope , Shotkin Paul
Published: March 2021

88-year-old male with recent history of mastoiditis status post
completing outpatient antibiotic regimen presented with worsening neck
pain. Found to have complications of cerebral venous sinus thrombosis,
skull base osteomyelitis and a retropharyngeal mass. This is the
eleventh case in medical literature reporting on this phenomenon.
Thrombotic thrombocytopenic purpura with COVID-19 as an unforeseen complication: A case report.
Authors: Mushtaq Muhammad Zain , Mahmood Saad Bin Zafar , Shaikh Usman , Ali Syed Ahsan
Published: March 2021

This article reports an association of thrombotic thrombocytopenic
purpura(TTP) with COVID-19. A 49-year old male presented with fever,
diarrhea and altered mentation, was found to have COVID-19. On sixth
hospital day, he developed thrombocytopenia, microangiopathic hemolytic
anemia with schistocytes on peripheral blood film and worsening renal
function signifying TTP.
Disaggregation of Future Regional Climate Model Data to Generate Future Rainfall Intensity-Duration-Frequency Curves to Assess Climate Change Impacts
Authors: Tayşi Hüsamettin , Ozger Mehmet
Published: March 2021

Heavy increase in urbanization, industrialization and population is
causing an increase in emissions of greenhouse gases (GHG) and this
causes variations in atmosphere. Climate change causes extreme rainfall
events and these events are expected to be enhanced in the future. Since
flooding is influencing urban areas, controlling and management of
flooding is a major necessity. Intensity-Duration-Frequency (IDF) curves
play a huge role in representing rainfall characteristics by linking
intensity, duration, and frequency of rainfall. Analysing short-duration
rainfall is crucial for urban areas due to fast responses of drainage
systems against heavy rainfall events. IDF curves were generated via the
Gumbel method for rainfalls from 5-min to 24-h in this study. However,
providing short-duration rainfall data is challenging due to the low
capacity, costs and geographic conditions. Therefore, the HYETOS
disaggregation model was applied to obtain sub-hourly data. IDF curves
are stationary since they only consider historical events. However, IDF
curves must be non-stationary and time varying based on preparation for
upcoming extreme events. This study aims to generate IDF curves under
climate change scenarios. The Regional Climate Model (RCM) HadGEM2-ES
generated under Representative Concentration Pathways (RCP) 4.5 and 8.5
scenarios and was used in the study to represent future rainfalls.
Future daily rainfalls were disaggregated into sub-hourly using
disaggregation parameters of corresponding station’s historical rainfall
data since it is impossible to estimate parameters when hourly data is
not available. With this new approach, future daily rainfall data is
disaggregated into 5-min data by complying with historical rainfall
patterns rather than complying with randomly selected rainfall
characteristics. The study concluded that future rainfall intensities
increases compared to historical IDF curves. RCP8.5 scenarios have
higher rainfall intensities for all return periods compared to RCP4.5
scenarios for all stations except a station. In addition, the accuracy
of the selected disaggregation model was verified.
Effectiveness of a modified Mediterranean diet recipe plus moderate exercise before and during pregnancy among women at high risk of gestational diabetes
Authors: Liu Fang , Hu Zhaohui , Dong Yinfang , Han Ke , Ding Xiaoyan
Published: March 2021

Background: Women with gestational diabetes mellitus (GDM) have elevated
risk of type 2 diabetes mellitus (T2DM). Several studies have indicated
healthy lifestyle reduces the prevalence of GDM. However, limited
evidence shows the association between Mediterranean diet (MD) and GDM
incidence in China. The aim of the current study was to establish a
Chinese-habit-based MD recipe and investigate the effects of the
modified MD on GDM. This trial recruited gestational age women who were
planning a pregnancy in the near future with at least one risk factor
for GDM. Methods: These participants were randomly assigned into the MD
group and control group. They were required to follow diet interventions
at least 6 months prior to pregnancy until delivery. Average dietary
intake, glucose and insulin metabolism in 26-28-week of gestation,
maternal and neonatal outcomes in each group were analyzed to assess the
effects of MD. We analyzed the clinical outcomes of 580 participants,
294 in the MD group and 286 in the control group. Results: The MD group
had a high intake of protein, vitamins, and dietary fibers, whereas low
intake of fat, resulting in improved insulin and glucose metabolism.
Meanwhile, women and their newborns in the MD group showed a reduced
proportion of complications. Conclusion: The modified MD intervention
started before pregnancy shows a preventive effect on GDM, also benefits
the mother and their newborns in other outcomes.
Single Input LC Series Resonant Converter Based High Brightness Light Emitting Diode Driver with ZVS
Authors: Udumula Ramanjaneya Reddy
Published: March 2021

This work proposes a high brightness light emitting diode (HB-LED)
driver circuit based on a full-bridge LC series resonant converter with
series DC bus for low power applications with a dimming feature. The
proposed configuration consists of full-bridge LC series resonant
converter with a series DC bus. The idea behind the concept is to supply
the light emitting diode (LED) threshold voltage directly from the
constant DC bus - and the control voltage, which is used for current
regulation, is supplied through a full-bridge LC resonant converter.
Since the control voltage responsible for current regulation is only
processed by the full-bridge series resonant converter, the conduction
loss is less even if several LED strings are connected to the same
converter. The proposed HB-LED driver is characterized by low switching
loss, reduced component count, high efficiency, and reduction of output
electrolytic capacitor. Further, double pulse width modulation (DPWM)
dimming control is designed and used to control the average output
currents. The proposed high brightness light emitting diode (HB-LED)
driver circuit based on a full-bridge LC series resonant converter is
simulated using Orcad/PSpice software. The theoretical analysis and
predictions of the proposed full-bridge series resonant converter-based
HB-LED driver is in close agreement with the results obtained.
Bilateral lung transplantation (BLTx) in a 9-year-old girl with bronchopulmonary dysplasia with pulmonary hypertension
Authors: Ota Chiharu , Saito Ryoko , Tominaga Junya , Iwasawa Shinya , Takashi Hirama , Matsuda Yasushi , Ono Katsunori , Onoki Takehiko , Kimura Masato , Kawabata Yoshinori , Okada Yoshinori
Published: March 2021

Background Bronchopulmonary dysplasia (BPD) is a chronic respiratory
disease that occurs in premature infants and the prognosis is variable
depending on the comorbidities including fibrosis, emphysema, or
pulmonary hypertension (PH). We present a case of a 9-year-old girl who
developed PH associated with severe BPD (BPD-PH) and underwent bilateral
lung transplantation (BLTx). Case description A 9-year-old girl admitted
to our department to undergo BLTx. She was born at 23 weeks and 4 days
gestation with a weight of 507 grams. She received ventilation for the
first 2 months and required further respiratory care due to repetitive,
severe respiratory infections. She was diagnosed with BPD-PH at 6 months
of age and oral administration of pulmonary vasodilators were initiated.
She was registered as a lung transplant candidate at 4 years of age
after the life-threatening exacerbation. Chest computed tomography (CT)
revealed severe lung conditions with ground-glass opacities and
emphysematous low-density areas in the upper and lower lobes. BLTx from
a brain-dead male donor was performed. The pathological findings of her
resected lung revealed saccular, hypoplastic lung with alveolar
repair/regeneration and medial hypertrophy and muscularization of
peripheral arteries. The postoperative course was mostly uneventful. She
was free from oxygen administration and showed no signs of PH after 6
months of the surgery. Conclusion This is the first case report of BLTx
in a pediatric, irreversible BPD-PH patient with detailed
pathohistological findings and clinical examination. Lung
transplantation is one of the treatment options for severe BPD-PH.
Pseudoanalytic extension on F(p,p-2,s) spaces and applications
Authors: Qian Ruishen
Published: March 2021

In this paper, we generalized the main results in [9]. As an applications, we
give a characterization of the closure of F(p,p-2,s) spaces in
Lipschitz-type spaces A? by pseudoanalytic extension.
More on Arhangel’skiĭ sheaf amalgamations
Authors: Liu Meiyan , Yu Jiakui , Zhang Shuguo
Published: March 2021

We proceed to consider the topic of ideal-convergence. In particular, we
introduce the ideal-version of Arhangel?ski? sheaf amalgamations, and exam
the relations among the ideal-version of Arhangel?ski? sheaf amalgamations,
ideal-version of QN-spaces and ideal-version of covering properties. Some
characterizations of ideal-version of Arhangel?ski? sheaf amalgamations
will be given. Our observations extend some classic results.
Further results of special elements in rings with involution
Authors: Mosic Dijana , Xu Sanzhang , Benítez Julio
Published: March 2021

In this paper, we consider Moore-Penrose invertible, group invertible, and
core invertible elements in rings with involution to characterize EP,
generalized normal, generalized Hermitian elements and generalized partial
isometries. As a consequence, we obtain new characterizations for elements
in rings with involution to be normal and Hermitian elements.