bluuebunny/crossref_metadata_2025 huggingface dataset:
Expression of cysteinyl leukotriene receptor 1 and 2 (CysLTR1 and CysLTR2) in the lymphocytes of hyperplastic tonsils: comparison between allergic and nonallergic snoring children
Authors: Paulucci Bruno Peres , Pereira Juliana , Picciarelli Patricia , Levy Debora , Di Francesco Renata Cantisani
Published: May 2016

Background

Cysteinyl leukotriene receptor 1 and 2 (CysLTR1 and CysLTR2) are involved in allergic processes and play a role in adenotonsillar hyperplasia (AH). Clinically, only CysLTR1 may be blocked by montelukast. Our objective was to compare the expression of CysLTR1 and CysLTR2 in the B and T cells of hyperplasic tonsils of sensitized (SE) and control (NS) snoring children.

Methods

Sixty children, 5 to 10 years of age, referred for adenotonsillectomy, were divided into SE and NS groups, according to their responses to the skin‐prick test. Cells from the removed tissues were stained for CysLTR1, CysLTR2, CD19, and CD3 and counted via flow cytometry. messenger RNA (mRNA) expression of the CysLTRs genes was measured real‐time quantitative reverse transcription polymerase chain reaction (RT‐qPCR).

Results

The SE group showed reduced expression of the small CD3+/CysLTR1+ lymphocytes (4.6 ± 2.2 vs 6.5 ± 5.0; p = 0.04). Regarding the large lymphocytes, the SE group showed lower expression of CD3+/CysLTR1+ (40.9 ± 14.5 vs 47.6 ± 11.7; p = 0.05), CD19+/CysLTR1+ (44.6 ± 16.9 vs 54.1 ± 12.4; p = 0.01), and CD19+/CysLTR2+ (55.3 ± 11.3 vs 61.5 ± 12.6; p = 0.05) lymphocytes. Considering the total number of lymphocytes, the SE group had fewer CD3+/CysLTR1+ lymphocytes (11.1 ± 5.5 vs 13.7 ± 6.2; p = 0.04). All other cell populations exhibited reduced expression in the SE group without statistical significance. The expression of CysLTR2 was significantly higher (p < 0.05) than CysLTR1 in most studied cell populations. The mRNA expression did not show significant differences between the groups.

Conclusion

The expression of CysLTR is higher in the lymphocytes of the NS children, and CysLTR2 shows greater expression than CysLTR1 Respiratory allergies do not appear to be a stimulus for AH occurrence. Newer drugs capable of blocking both CysLTRs warrant further study.
The Nanoparticle Size Effect in Graphene Cutting: A “Pac‐Man” Mechanism
Authors: Qiu Zongyang , Song Li , Zhao Jin , Li Zhenyu , Yang Jinlong
Published: May 2016

Metal‐nanoparticle‐catalyzed cutting is a promising way to produce graphene nanostructures with smooth and well‐aligned edges. Using a multiscale simulation approach, we unambiguously identified a “Pac‐Man” cutting mechanism, characterized by the metal nanoparticle “biting off” edge carbon atoms through a synergetic effect of multiple metal atoms. By comparing the reaction rates at different types of edge sites, we found that etching of an entire edge carbon row could be triggered by a single zigzag‐site etching event, which explains the puzzling linear dependence of the overall carbon‐atom etching rate on the nanoparticle surface area observed experimentally. With incorporation of the nanoparticle size effect, the mechanisms revealed herein open a new avenue to improve controllability in graphene cutting.
Linking small pelagic fish and cetacean distribution to model suitable habitat for coastal dolphin species, Delphinus delphis and Tursiops truncatus, in the Greek Seas (Eastern Mediterranean)
Authors: Giannoulaki Marianna , Markoglou Evangelia , Valavanis Vasilis D. , Alexiadou Paraskevi , Cucknell Anna , Frantzis Alexandros
Published: May 2016

A large‐scale assessment of the summertime suitable habitat for Delphinus delphis (short‐beaked common dolphin) and Tursiops truncatus (common bottlenose dolphin) in Greek Seas (Eastern Mediterranean) was conducted using data from dedicated and opportunistic cetacean surveys and published data records.

Using a presence/absence approach, generalized additive models were applied to define a suite of environmental, bathymetric and biotic factors that best describe common and bottlenose dolphin spatial distribution, during early (May, June, July) and late (August, September) summer.

A geographic information system (GIS) was used to integrate sightings data with environmental characteristics, distance from the coast and sardine probability of presence. These variables were considered as good proxies for defining species‐suitable habitat within the study area's coastal environment.

The final selected models were used to produce annual probability maps of the presence of the species in the entire Greek Seas, as a measure of habitat suitability. Based on the mean probability and standard deviation maps for the study period GIS techniques were subsequently used to determine the persistent (areas with high mean and low variation) and occasional (high mean and high variation) habitat of each species.

Results showed that there was a high probability of common dolphin presence in areas with a high probability of sardine presence. For bottlenose dolphin, higher probability of the presence of species occurred in areas closer to the shore, with a high probability of sardine presence and with high concentrations of chlorophyll‐a.

In both seasons, the North Aegean Sea and the Inner Ionian Sea Archipelago were indicated as the most suitable areas for common dolphin distribution. Persistent habitat areas of the bottlenose dolphin included enclosed seas, continental shelf waters, and waters surrounding islands. The indicated suitable areas are discussed along with deficiencies of the models and future implications for conservation.

Copyright © 2016 John Wiley & Sons, Ltd.
Transitions in the Molecular Configuration and Aggregates for Mixtures of a Star‐Shaped Hexameric Cationic Surfactant and a Monomeric Anionic Surfactant
Authors: Qiao Fulin , Wang Meina , Liu Zhang , Fan Yaxun , Wang Yilin
Published: May 2016

A hexameric cationic ammonium surfactant (PAHB), in which six amphiphilic moieties were connected by a star‐shaped spacer group, adopted star‐shaped, claw‐like, and pyramid‐like molecular configurations in aqueous solution, depending on the concentration. Herein, we studied the effect of adding sodium dodecyl sulfate (SDS) on the configuration and aggregation behavior of PAHB. Taking these three configurations of PAHB as initial states, the addition of SDS caused transitions of the star‐shaped and claw‐like configurations into a pyramid‐like configuration, whilst the pyramid‐like configuration remained unchanged. Moreover, the SDS/PAHB aggregates experienced transition from small spheres to large spherical fingerprint‐like aggregates, no matter the initial state of PAHB. Molecular packing in the aggregates was also studied. These results have improved our understanding about the cooperative interactions between star‐shaped oligomeric surfactants and monomeric surfactants, which should guide future applications of this unique type of surfactant.
Prevalence and associated features of autism spectrum disorder in extremely low gestational age newborns at age 10 years
Authors: Joseph Robert M. , O'Shea Thomas M. , Allred Elizabeth N. , Heeren Tim , Hirtz Deborah , Paneth Nigel , Leviton Alan , Kuban Karl C. K.
Published: May 2016

We sought to estimate the prevalence of autism spectrum disorder (ASD) in children born extremely preterm relative to the U.S. population risk of 1.5% [CDC, 2014] using the best‐available diagnostic procedures and minimizing confounding with other neurodevelopmental impairments. Eight hundred and eighty nine of 966 (92%) 10‐year‐old children from the Extremely Low Gestational Age Newborn birth cohort, delivered at 23–27 weeks gestation in 2002–2004, participated. Children meeting ASD screening criteria on the Social Communication Questionnaire were evaluated with the Autism Diagnostic Interview–Revised (ADI‐R). Those meeting ADI‐R criteria were assessed with the Autism Diagnostic Observation Schedule‐2 (ADOS‐2). A positive ADOS‐2 score was the criterion for ASD. Twenty‐six participants were not assessed for ASD because of severe sensory or motor impairment. In the remaining sample, 61 children met criteria for ASD, resulting in a prevalence of 7.1% (95% CI = 5.5–9.0). ASD risk decreased with increasing gestational age, from 15.0% (95% CI = 10.0–21.2) for 23–24 weeks, 6.5% (95% CI = 4.2–9.4) for 25–26 weeks, to 3.4% (95% CI = 1.6–6.1) for 27 weeks gestational age, and this association was independent of IQ. Among children with ASD, 40% had intellectual disability. The male‐to‐female ratio of children with ASD was 2.1:1 (95% CI = 1.2:1–3.5:1), lower than in the general population (4:1). ASD prevalence in the ELGAN cohort was four times higher than in the general population, and was strongly associated with gestational age, underscoring the need for enhanced ASD screening of children born preterm, and suggesting that some risk factors associated with preterm birth may also play a role in the etiology of autism. Autism Res 2017, 10: 224–232. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.
Essential strategies to optimize asymmetric PCR conditions as a reliable method to generate large amount of ssDNA aptamers
Authors: Heiat Mohammad , Ranjbar Reza , Latifi Ali Mohammad , Rasaee Mohammad Javad , Farnoosh Gholamreza
Published: May 2016

Asymmetric PCR, a simple method to generate single‐stranded DNA (ssDNA) aptamers in systematic evaluation of ligand by exponential enrichments rounds, is coupled with limitations. We investigated the essential strategies for optimization of conditions to perform a high‐quality asymmetric PCR. Final concentrations of primers and template, the number of PCR cycles, and annealing temperature were selected as optimizing variables. The qualities of visualized PCR products were analyzed by ImageJ software. The highest proportion of interested DNA than unwanted products was considered as optimum conditions. Results revealed that the best values for primers ratio, final template concentration, annealing temperature, and PCR cycles were, respectively, 30:1, 1 ng/μL, 55 °C, and 20 cycles for the first and 50:1, 2 ng/μL, 59 °C, and 20 cycles for other rounds. No significant difference was found between optimized asymmetric PCR results in the rounds of two to eight (P > 0.05). The ssDNA quality in round 10 was significantly better than other rounds (P < 0.05). Generally, the ssDNA product with less dimers, double‐stranded DNA (dsDNA), and smear are preferable. The dsDNA contamination is the worst, because it can act as antidote and inhibits aptameric performance. Therefore, to choose the best conditions, the lower amount of dsDNA is more important than other unwanted products.
Prospective study of pregnancy and newborn outcomes in mothers with West nile illness during pregnancy
Authors: Pridjian Gabriella , Sirois Patricia A. , McRae Scott , Hinckley Alison F. , Rasmussen Sonja A. , Kissinger Patricia , Buekens Pierre , Hayes Edward B. , O'Leary Dan , Kuhn Stephanie , Swan Kenneth F. , Xiong Xu , Wesson Dawn M.
Published: May 2016

Background

A previous case report of West Nile virus (WNV) illness during pregnancy suggested that WNV could be a cause of congenital defects. We performed a prospective, longitudinal cohort study of pregnant women with WNV illness to increase our knowledge of the effects of WNV illness during pregnancy.

Methods

Participants were enrolled in 2005 to 2008 from pregnant women with serologically confirmed WNV illness reported to the Centers for Disease Control and Prevention. Comparison was made to WNV‐uninfected women, matched on maternal age and enrollment month. Pregnancy and newborn data were collected; cord blood WNV serology was obtained. Pediatric exams and the Bayley Scales of Infant and Toddler Development‐Third Edition (Bayley‐III) were performed.

Results

Twenty‐eight WNV‐infected mothers and 25 WNV‐uninfected mothers participated. Maternal demographics were similar except for a higher rate of planned pregnancies, education, and household income in the WNV‐uninfected mothers. There were no differences in pregnancy and delivery characteristics except that infected mothers had a higher incidence of febrile illnesses and used more medications. Birth weight, length, head circumference, and rate of congenital malformations were similar in babies born to WNV‐infected and ‐uninfected mothers. Follow‐up physical exams were generally normal. The Bayley‐III assessments, available for 17 children born to mothers with WNV illness, showed performance at or above age level across domains.

Conclusion

The risk for adverse pregnancy and newborn outcomes in women experiencing WNV illness in pregnancy appears to be low, but future studies with larger numbers are needed to rule out a small risk. Birth Defects Research (Part A) 106:716–723, 2016. © 2016 Wiley Periodicals, Inc.
Mechanoluminescence of SrAl2O4:Eu,Dy nanophosphors induced by low impact velocity
Authors: Jha Piyush , Chandra B.P.
Published: May 2016

The present paper reports the impulsive excitation of mechanoluminescence (ML) in Sr0.97Al2O4:Eu0.01,Dy0.02 nanophosphors prepared using a combustion technique. The phosphors are characterized using X‐ray powder diffraction (XRD), high‐resolution transmission electron microscopy (HRTEM) and photoluminescence (PL). The XRD results show that the samples exhibit a monoclinic α‐phase in the crystal structure. The space group of SrAl2O4:Eu,Dy nanophosphors is monoclinic P21. The PL and ML spectra of SrAl2O4:Eu,Dy nanophosphors are excited using light with a wavelength of 365 nm and emission is found at 516 nm. The prepared nanophosphors exhibits an intense ML that can be seen in daylight with the naked eye. When a sample powder is deformed impulsively by the impact of a moving piston, the ML intensity initially increases linearly with time, attains a peak value, Im, at time tm, and then decreases with time. The peak ML intensity, Im, and total ML intensity, IT, increase linearly with applied pressure and impact velocity. The ML intensity decreases with successive impacts of load onto the phosphors, and the diminished ML intensity can be approximately recovered by UV irradiation. The activation energy using thermoluminescence is found to be 0.57 eV for SrAl2O4:Eu,Dy nanophosphors. Copyright © 2016 John Wiley & Sons, Ltd.
Nomogram to predict perioperative blood transfusion for hepatopancreaticobiliary and colorectal surgery
Authors: Kim Y , Bagante F , Gani F , Ejaz A , Xu L , Wasey J O , Johnson D J , Frank S M , Pawlik T M
Published: May 2016

Background

Predictive tools assessing risk of transfusion have not been evaluated extensively among patients undergoing complex gastrointestinal surgery. In this study preoperative variables associated with blood transfusion were incorporated into a nomogram to predict transfusion following hepatopancreaticobiliary (HPB) or colorectal surgery.

Methods

A nomogram to predict receipt of perioperative transfusion was developed using a cohort of patients who underwent HPB or colorectal surgery between January 2009 and December 2014. The discriminatory ability of the nomogram was tested using the area under the receiver operating characteristic (ROC) curve and internal validation performed via bootstrap resampling.

Results

Among 4961 patients undergoing either a HPB (56·3 per cent) or colorectal (43·7 per cent) resection, a total of 1549 received at least 1 unit of packed red blood cells, giving a perioperative transfusion rate of 31·2 per cent. On multivariable analysis, age 65 years and over (odds ratio (OR) 1·52), race (versus white: black, OR 1·58; Asian, OR 1·86), preoperative haemoglobin 8·0 g/dl or less (versus over 12·0 g/dl: OR 26·79), preoperative international normalized ratio more than 1·2 (OR 2·44), Charlson co-morbidity index score over 3 (OR 1·86) and procedure type (versus colonic surgery: major hepatectomy, OR 1·71; other pancreatectomy, OR 2·12; rectal surgery, OR 1·39; duodenopancreatectomy, OR 2·65) were associated with a significantly higher risk of transfusion and were included in the nomogram. A nomogram was constructed to predict transfusion using these seven variables. Discrimination and calibration of the nomogram revealed good predictive abilities (area under ROC curve 0·756).

Conclusion

The nomogram predicted blood transfusion in major HPB and colorectal surgery.
Prognosis of patients with colonic carcinoma before, during and after implementation of complete mesocolic excision
Authors: Merkel S , Weber K , Matzel K E , Agaimy A , Göhl J , Hohenberger W
Published: May 2016

Background

The implementation of complete mesocolic excision (CME) for colonic cancer was accompanied by other important changes, including more patients with early diagnosis by screening and the introduction of adjuvant chemotherapy in patients with stage III disease. The contribution of CME remains unclear.

Methods

In this observational study, data from patients with stage I–III colonic carcinoma were analysed by comparing five time intervals: 1978–1984 (pre-CME), 1985–1994 (CME development), 1995–2002 (CME implementation), 2003–2009 (CME) and 2010–2014 (CME), with a special focus on indicators of process and outcome quality.

Results

During the observed periods, the median age of patients increased (from 65 to 67 years), there were more right-sided carcinomas (from 17·0 to 32·4 per cent), more stage I disease (from 14·0 to 27·7 per cent) and fewer patients with regional lymph node metastases (from 42·7 to 32·0 per cent). The proportion of patients with pN0 disease and at least 12 examined regional lymph nodes increased (from 84·8 to 100 per cent) as did the R0 resection rate (from 97·0 to 100 per cent). Overall morbidity increased, whereas the in-hospital mortality rate was stable (range 1·8–3·7 per cent). Use of adjuvant chemotherapy in stage III colonic carcinoma increased from 0 to 79 per cent. The improvement in outcome quality was more evident in stage III than in stage I–II tumours. In stage III, the 5-year locoregional recurrence rate decreased from 14·8 to 4·1 per cent (P = 0·046) and the 5-year cancer-related survival rate increased from 61·7 to 80·9 per cent (P = 0·010).

Conclusion

With CME, the quality indicators of process and outcome quality improved, especially in stage III colonic carcinoma. Adjuvant chemotherapy in stage III and multidisciplinary approaches in patients with metachronous distant metastases contributed to further outcome improvement.
Risk factors for requiring cholecystectomy for gallstone disease in a prospective population-based cohort study
Authors: Talseth A , Ness-Jensen E , Edna T-H , Hveem K
Published: May 2016

Background

The relationship between different lifestyle factors and the risk of needing cholecystectomy for gallstone disease is not clear. This study aimed to assess the association between anthropometric, lifestyle and sociodemographic risk factors and the subsequent risk of requiring cholecystectomy for gallstone disease during long-term follow-up in a defined population cohort.

Methods

Data from a large population-based cohort study performed from 1995 to 1997 were used (the second Norwegian Nord-Trøndelag health study, HUNT2). Following HUNT2, from 1998 to 2011, all patients operated on for gallstone disease with cholecystectomy at the two hospitals in the county, Levanger Hospital and Namsos Hospital, were identified. A Cox proportional hazards model was used for multivariable risk analysis.

Results

The HUNT2 cohort included 65 237 individuals (69·5 per cent response rate), aged 20–99 years. During a median follow-up of 15·3 (range 0·6–16·4) years, 1162 cholecystectomies were performed. In multivariable analysis, overweight individuals (body mass index (BMI) 25·0–29·9 kg/m2) had a 58 per cent increased risk of cholecystectomy compared with individuals with normal weight (BMI less than 25·0 kg/m2). Obese individuals (BMI 30 kg/m2 or above) had a twofold increased risk. Increasing waist circumference independently increased the risk of cholecystectomy. In women, current hormone replacement therapy (HRT) increased the risk, whereas hard physical activity and higher educational level were associated with reduced risk of cholecystectomy.

Conclusion

High BMI and waist circumference increased the risk of having cholecystectomy for both sexes. In women, the risk was increased by HRT, and decreased by hard physical activity and higher educational level.
Regio‐ and Enantioselective Sequential Dehalogenation ofrac‐1,3‐Dibromobutane by Haloalkane Dehalogenase LinB
Authors: Gross Johannes , Prokop Zbyněk , Janssen Dick , Faber Kurt , Hall Mélanie
Published: May 2016

The hydrolytic dehalogenation ofrac‐1,3‐dibromobutane catalyzed by the haloalkane dehalogenase LinB fromSphingobium japonicumUT26 proceeds in a sequential fashion: initial formation of intermediate haloalcohols followed by a second hydrolytic step to produce the final diol. Detailed investigation of the course of the reaction revealed favored nucleophilic displacement of thesec‐halogen in the first hydrolytic event with pronouncedRenantioselectivity. The second hydrolysis step proceeded with a regioselectivity switch at the primary position, with preference for theSenantiomer. Because of complex competition between all eight possible reactions, intermediate haloalcohols formed with moderate to goodee((S)‐4‐bromobutan‐2‐ol: up to 87 %). Similarly, (S)‐butane‐1,3‐diol was formed at a maximumeeof 35 % before full hydrolysis furnished the racemic diol product.
New Red‐Emitting Tetrazine‐Phenoxazine Fluorogenic Labels for Live‐Cell Intracellular Bioorthogonal Labeling Schemes
Authors: Knorr Gergely , Kozma Eszter , Herner András , Lemke Edward A. , Kele Péter
Published: May 2016

The synthesis of a set of tetrazine‐bearing fluorogenic dyes suitable for intracellular labeling of proteins in live cells is presented. The red excitability and emission properties ensure minimal autofluorescence, while through‐bond energy‐transfer‐based fluorogenicity reduces nonspecific background fluorescence of unreacted dyes. The tetrazine motif efficiently quenches fluorescence of the phenoxazine core, which can be selectively turned on chemically upon bioorthogonal inverse‐electron‐demand Diels–Alder reaction with proteins modified genetically with strained trans‐cyclooctenes.
Straightforward and Controlled Shape Access to Efficient Macrocyclic Imidazolylboronium Anion Receptors
Authors: Toure Momar , Charles Laurence , Chendo Christophe , Viel Stéphane , Chuzel Olivier , Parrain Jean‐Luc
Published: May 2016

A straightforward synthesis of air‐ and water‐stable bis‐cationic macrocyclic imidazolylboronium anion receptors is described herein. By taking advantage of the bulky and rigid 9‐borabicyclo[3.3.1]‐nonane (9‐BBN) attaching point and a well‐designed bis‐imidazolylaryl, highly stable dimeric imidazolylboronium macrocycles were synthesized. Additionally, NMR spectroscopy (1H, DOSY, and HOESY), mass spectrometry (MS), and X‐ray diffraction studies revealed that these macrocyclic scaffolds can bind several monoanions with high association constants in DMSO, and are particularly sensitive for the MS detection of anions (with concentrations in the nm range). This anion/receptor interaction involves eight C−H binding sites, which include C
−H and unusual Csp3−H hydrogen‐bonding donors.
Multifaceted Studies of the DNA Interactions and In Vitro Cytotoxicity of Anticancer Polyaromatic Platinum(II) Complexes
Authors: Pages Benjamin J. , Sakoff Jennette , Gilbert Jayne , Rodger Alison , Chmel Nikola P. , Jones Nykola C. , Kelly Sharon M. , Ang Dale L. , Aldrich‐Wright Janice R.
Published: May 2016

This study reports a detailed biophysical analysis of the DNA binding and cytotoxicity of six platinum complexes (PCs). They are of the type [Pt(PL)(SS‐dach)]Cl2, where PL is a polyaromatic ligand and SS‐dach is 1S,2S‐diaminocyclohexane. The DNA binding of these complexes was investigated using six techniques including ultraviolet and fluorescence spectroscopy, linear dichroism, synchrotron radiation circular dichroism, isothermal titration calorimetry and mass spectrometry. This portfolio of techniques has not been extensively used to study the interactions of such complexes previously; each assay provided unique insight. The in vitro cytotoxicity of these compounds was studied in ten cell lines and compared to the effects of their R,R enantiomers; activity was very high in Du145 and SJ‐G2 cells, with some submicromolar IC50 values. In terms of both DNA affinity and cytotoxicity, complexes of 5,6‐dimethyl‐1,10‐phenanthroline and 2,2′‐bipyridine exhibited the greatest and least activity, respectively, suggesting that there is some correlation between DNA binding and cytotoxicity.
ChemInform Abstract: Synthesis and Physiological Activity of 2,3,6‐Triaryl‐4‐oxo(hydroxy, oximino, amino)piperidines.
Authors: MOBIO I. G. , SOLDATENKOV A. T. , FEDOROV V. O. , AGEEV E. A. , SERGEEVA N. D. , LIN S. , STASHENKO E. E. , PROSTAKOV N. S. , ANDREEVA E. I. , MINAEV L. I. , KOL'TSOVA S. S. , DENISOV E. N. , KAPITONENKO T. A. , OVODENKO L. A.
Published: May 2016

Cocondensation of the benzaldehyde (I) with methyl benzyl ketone (II) in the presence of ammonium acetate (III) gives the piperidones (IV).
ChemInform Abstract: The Oxide Ion Conductivity in Ln5Mo3O16+x (Ln: La, Pr, Nd, Sm, Gd; x ≅0.5) with a Fluorite‐Related Structure
Authors: TSAI M. , GREENBLATT M. , MCCARROLL W. H.
Published: May 2016

is studied by ac impedance methods over the temp. range 250‐700 °C. All phases exhibit relatively high oxide ion conductivity; the highest values (comparable with those of yttria‐stabilized zirconia) are found for La5Mo3O16+x. The oxygen content of the phases varies in the range 0 ≤ x ≤ 0.5.
ChemInform Abstract: Cyclization Reactions of Nitriles. Part 34. Transformation of 4‐Aryl‐2,6‐diamino‐3,5‐dicyano‐4H‐thiopyrans into Substituted 4‐Aryl‐3‐cyano‐2(1H)‐pyridinethiones and 2‐Amino‐4‐aryl‐7,7‐dimethyl‐5‐oxo‐3‐cyano‐5,6,7,8‐tetrahydro‐4H‐benzo(b)pyrans.
Authors: SHARANIN YU. A. , SHESTOPALOV A. M.
Published: May 2016

The reaction between the thiopyrans (I) and the monoketones or acyclic 1,3‐dicarbonyl compounds (II) proceeds via elimination of malononitrile from the thiopyran moiety to afford the pyridinethiones (III).
ChemInform Abstract: Direct Formation of (CH3)2HSiCl from Silicon and CH3Cl.
Authors: MAGRINI K. A. , FALCONER J. L. , KOEL B. E.
Published: May 2016

Compared to the reaction on polycrystalline Si surfaces, the evaporation of Cu on Si surfaces reduces the reaction rates for the formation of (III) and (IV) but increases the selectivity of formation of (III) up to 90%.
ChemInform Abstract: Development of Synthetic Compounds with Glutathione Peroxidase Activity.
Authors: WILSON S. R. , ZUCKER P. A. , HUANG R.‐R. C. , SPECTOR A.
Published: May 2016

Glutathione peroxidase is the major defense in the lens of the eye against hydrogen peroxide.
ChemInform Abstract: Optical Spectroscopic and Structural Properties of V3+‐Doped Fluoride, Chloride, and Bromide Elpasolite Lattices.
Authors: REBER C. , GUEDEL H. U. + , MEYER G. , SCHLEID T. , DAUL C. A.
Published: May 2016

The crystal structures of the elpasolites (I)‐(VII) are determined by using XRD.
ChemInform Abstract: Synthesis and Biological Activity of 1‐Aroyl‐5‐(p‐sulfamoylphenylazo)‐3,4‐dimethylpyrano(2,3‐c)pyrazol‐6(1H)‐ones.
Authors: HOGALE M. B. , PAWAR B. N.
Published: May 2016

The hydrazones (I) are thermally cyclized, forming the pyrazolones (II).
ChemInform Abstract: Fabrication of Metal‐Layer (Nickel) Silicate Microcomposite Particles by a Surface‐Nucleated Precipitation Route.
Authors: OHTSUKA K. , KOGA J. , SUDA M. , ONO M.
Published: May 2016

It is demonstrated that microcomposite powders consisting of sodium fluoride tetrasilicic mica (NaMg2.5Si4O10F2) uniformly covered with Ni metal particles can be prepared by deposition of a Ni(II) basic salt on the surface of the clay and subsequent reduction (deposition from Ni(NO3)2 solutions by hydrolysis of urea at 92 °C, reduction in H2 at 400‐700 °C).
ChemInform Abstract: Further Theoretical Studies on B2H4 and B2H+ 4.
Authors: CURTISS L. A. , POPLE J. A.
Published: May 2016

Ab initio calculations at the G1 level of theory are consistent with a doubly bridged C2v structure of B2H4 and its ionization to B2H4+.
ChemInform Abstract: Crystallographic Data and Morphology of K2SO4·7 KHSO4·H2O and the Ternary System K2SO4‐H2SO4‐H2O at 25 °C.
Authors: BOURGUIBA N. , JOUINI T.
Published: May 2016

Published data on the composition of a salt existing in the title system at room temp. are very inconsistent.
ChemInform Abstract: Synthesis and Characterization of (Ca2‐xEux)RuH6.
Authors: MOYER R. O. JUN. , LINDSAY R. , STOREY D. F.
Published: May 2016

The quaternary metal hydrides (Ca2‐xEux)RuH6 (I) (0 ≦ x ≦ 2) are synthesized from stoichiometric mixtures of EuH2, CaH2 and Ru powders heated in a hydrogen atmosphere at 800 °C. Samples of (I) are investigated by powder XRD, resistivity measurements and magnetic susceptibility measurements.
ChemInform Abstract: Thermophysical Properties of the Lanthanide Sesquisulfides. Part 1. Schottky Functions and Magnetic and Electronic Properties of γ‐La2S3, γ‐Ce2S3, γ‐Nd2S3, and γ‐Gd2S3.
Authors: WESTRUM E. F. JUN. , BURRIEL R. , GRUBER J. B. , PALMER P. E. , BEAUDRY B. J. , PLAUTZ W. A.
Published: May 2016

The heat capacities of the four title compounds are measured in the range 6‐350 K by adiabatic calorimetry.
ChemInform Abstract: Ammine Ligand Exchange in Tetraamminepalladium(II) in Aqueous Solution
Authors: BROENNUM B. , JOHANSEN H. S. , SKIBSTED L. H.
Published: May 2016

(NH3/NH4Cl) is studied by 15N‐labeling experiments over the pH range 6‐11. The observed pH dependence of the ligand exchange rate is interpreted in terms of two parallel reactions, a direct exchange between NH3 and (Pd(NH3)4)2+ predominant in alkaline solution, and an indirect exchange predominant in neutral solutions, that involves the transient formation of (Pd(NH3)3(H2))2+.
ChemInform Abstract: ESR Study of Supported H3PMo12O40/K3PMo12O40 Catalysts for the Oxidation of Acrolein.
Authors: SERWICKA E. M.
Published: May 2016

The phenomenon of thermal stabilization of heteropoly acids with a Keggin anion is investigated by means of ESR technique for systems obtained by impregnation of the K3PMo12O40 support with different amounts of the H3PMo12O40 phase (1‐10 monolayers).
ChemInform Abstract: Formation of Silico‐Antimonic Core‐Shell Particles with an Antimonic Acid Core Encapsulated with Silica
Authors: KONE M. , COURTIN P. , LEMERLE J.
Published: May 2016

is studied using three different synthetic routes: mixing of antimonic and silicic acid (route A), mixing of their potassium salts followed by protonation (B), and hydrolysis of a tetraethoxysilane solution in ethanol by an aqueous antimonic acid solution (C).
ChemInform Abstract: Heteronuclear Diatomic Transition‐Metal Cluster Ions in the Gas Phase: Reactions of ScFe+ with Hydrocarbons.
Authors: LECH L. M. , GORD J. R. , FREISER B. S.
Published: May 2016

Fourier transform mass spectrometry shows that the title cluster ion is reactive with various alkenes but unreactive with alkanes.
ChemInform Abstract: High Relative Reactivities of Aromatic Cation Radicals Compared to Related Carbocations. Observation of an Unexpected Deuterium Kinetic Isotope Effect.
Authors: REITSTOEEN B. + , NORRSELL F. , PARKER V. D.
Published: May 2016

Attack by the acetate ion (II) on the cation radical derived from (I) leads to the adduct (III).
ChemInform Abstract: Anchimeric Assistance by the Oxiranyl Group: Mild Alkanolysis of an Enol Ether.
Authors: SANGWAN N. K.
Published: May 2016

The base‐catalyzed alkanolysis of the oxiranylmethyl enol ether (I) using imidazole or NaOH as base gives the products (III) by anchimeric assistance of the oxiranyl group of (I).
ChemInform Abstract: Sonochemical Hydrodimerization of Aromatic Carbonyl Compounds.
Authors: BANERJI A. , NAYAK S. K.
Published: May 2016

The reductive coupling of the carbonyl compounds (I) mediated through ultrasonically generated ketyl anions (II) yields pinacols (III) which are known to be useful synthetic intermediates.
ChemInform Abstract: Aminophosphine Phosphinites of Propranolol as Ligands for Rhodium‐Catalyzed Asymmetric Hydrogenation of Dehydro Amino Acids.
Authors: KRAUSE H.‐W. , FOKEN H. , PRACEJUS H.
Published: May 2016

The optically pure enantiomers of the propranolol (I) are treated with chlorophosphines such as (II) to form aminophosphine phosphinite ligands such as (III).
ChemInform Abstract: Vilsmeier Reagents: Preparation of β‐Halo α,β‐Unsaturated Ketones.
Authors: MEWSHAW R. E.
Published: May 2016

The Vilsmeier agents (II), generated from dimethylformamide (I) and oxalyl chloride or bromide, react with the cycloalkane‐1,3‐diones (III) or (V), yielding the 3‐halocycloalkenones (IV) or (VI).
ChemInform Abstract: Modified Faujasite Zeolites as Catalysts in Organic Reactions: Esterification of Carboxylic Acids in the Presence of HY Zeolites.
Authors: CORMA A. , GARCIA H. , IBORRA S. , PRIMO J.
Published: May 2016

The esterification of phenylacetic and benzoic acids with EtOH, iPrOH, tBuOH, and p‐cresol is studied.
ChemInform Abstract: Aromatic Acetonylation by Using Aryltins with Acetonylium Equivalents Under the Palladium Catalysis.
Authors: KOSUGI M. , MIYAJIMA Y. , NAKANISHI H. , SANO H. , MIGITA T.
Published: May 2016

The Pd‐catalyzed reactions of the organo‐tin compound (I) with the allyl derivatives (II) or (IV) as acetonylium equivalents yield the compounds (III) or (V) hydrolysis of which provides phenylacetone (VI).
ChemInform Abstract: meta‐Photocycloaddition of trans‐1,2‐Dichloroethene to the Benzene Ring: Directed Cyclopropane Ring Formation in the Tricyclo(3.3.0.02,8)oct‐3‐ene Skeleton.
Authors: GILBERT A. , HEATH P. , RODWELL P. W.
Published: May 2016

1,2‐trans‐Dichloroethene (II) undergoes meta‐photocycloaddition to benzonitrile (I) and various other substituted benzenes to give adducts such as (IV)‐(VI) as major products possessing the tricyclo(3.3.0.02,8)oct‐3‐ene skeleton.
ChemInform Abstract: A New Synthesis of α,β‐Unsaturated Aldehydes.
Authors: NUZILLARD J.‐M. , BOUMENDJEL A. , MASSIOT G.
Published: May 2016

Coupling of chloroacetyl chloride (I) with O,N‐dimethylhydroxylamine hydrochloride (II) gives the hydroxamate (III) which is treated with triethyl phosphite (IV), forming N‐methoxy‐N‐methyldiethoxyphosphorylacetamide (V).
ChemInform Abstract: General Method to Trifluoromethyl Ketones. Part 1. Direct Alkylation of Ethyl Trifluoroacetylacetate.
Authors: AUBERT C. , BEGUE J.‐P. , CHARPENTIER‐MORIZE M. , NEE G. , LANGLOIS B.
Published: May 2016

Alkylation of the potassium (II) or sodium enolate (VI) of ethyl trifluoroacetylacetate (I) gives rise to the O‐ (III) and C‐alkylated products (IV) and (V).
ChemInform Abstract: 2,5‐Di‐tert‐butyl‐3,4‐dimethylpyrrole.
Authors: KUHN N. , JENDRAL K.
Published: May 2016

The 1,4‐diketone (I) is treated with ammonium acetate (II) in refluxing glacial acetic acid to form the title compound (III).
ChemInform Abstract: N‐Amino‐2‐pyridones from Acetohydrazide Derivatives.
Authors: APARICIO C. , MARTIN N. , QUINTEIRO M. , SEOANE C. , SOTO J. L. , VALDES J. A. , VELAZQUEZ S.
Published: May 2016

A variety of N‐aminopyridones such as (III) or (IV) are synthesized from the respective components (I) and (II) depending upon the cyclization taking place at the carbonyl or at the cyano group.
ChemInform Abstract: Synthesis of Optically Active 4‐Oxa‐1‐azabicyclo(4.1.0)heptan‐5‐ones.
Authors: KRUTIUS O. N. , EREMEEV A. V. , POLYAK F. D. , SHUSTOV G. V. , VOZNESENSKII V. N. , CHERVIN I. I. , KOSTYANOVSKII R. G.
Published: May 2016

The α,β‐dibromopropionic acid ester (I) reacts with the optically active α‐amino alcohols (II) to produce the epimeric aziridines (III) and (IV).
ChemInform Abstract: Iminoetheral and Iminothioetheral Derivatives of 1,5,6,7‐Tetrahydro‐2H‐1,4‐diazepines.
Authors: GURYN R.
Published: May 2016

The title diazepine derivatives (III), (VI) and (VIII) are key compounds in the synthesis of 1,4‐diazepano(2,1‐b)quinazolines.
ChemInform Abstract: The Synthesis and Molecular Structure of Tetra(isopropyl)silane.
Authors: ANDERSON D. G. , RANKIN D. W. H. , ROBERTSON H. E. , FRAZAO C. M. F. , SCHMIDBAUR H.
Published: May 2016

The title compound is prepared using literature methods, with the individual steps improved by changes in some of the experimental conditions.
ChemInform Abstract: Reactions of Ethyl and tert‐Butyl Tetraethyldiamidophosphite with tert‐Butyl Hypochlorite, N‐Chlorodiethylamine, and Propanesulfenyl Chloride.
Authors: GAZIZOV T. KH. , SAL'KEEVA L. K. , CHUGUNOV YU. V.
Published: May 2016

The diamidophosphites (I) are coupled with tert‐butyl hypochlorite or N‐chlorodiethylamine (IV) to give the chlorophosphates (II) exclusively or mixtures of (II) with the diamidophosphates (III) or the phosphoric triamide (V) depending on the solvent used.
ChemInform Abstract: Regiospecific Opening of Glycidyl Derivatives Mediated by Boron Trifluoride. Asymmetric Synthesis of Ether‐Linked Phospholipids.
Authors: GUIVISDALSKY P. N. , BITTMAN R.
Published: May 2016

The cleavage of the epoxides (‐)‐(I) with the alcohol (II) is catalyzed by boron trifluoride etherate to give regio‐ and stereoselectively the ethers (‐)‐(III).
ChemInform Abstract: The Reaction of Alkylphosphonic Acid Esters with Metals.
Authors: KOCH P. , RUMPEL H. , SUTTER P. , WEIS C. D.
Published: May 2016

Reaction of the dialkyl methylphosphonates (I) with the alkali metals (II) or magnesium (VI) is studied.
ChemInform Abstract: A New and Convenient Synthesis of Organosilylphosphines.
Authors: UHLIG W. , TZSCHACH A.
Published: May 2016

The reaction of PH3 (II) and organic phosphines such as (V) with trimethylsilyltriflate (I) leads to trimethylsilylphosphines of the type (III), (IV), and (VI) in high yields.
ChemInform Abstract: 1(3)‐Chloro‐2‐(methoxycarbonylhydrazono)propylphosphonates: Reagents for the Alkylation of Ketone Enolates. Access to Pyrrolylmethylphosphonates and β,ε‐Diketo Phosphonate Precursors of Cyclopentenones.
Authors: HAELTERS J. P. , CORBEL B. , STURTZ G.
Published: May 2016

The chloro hydrazono phosphonates (I) and (IV) react with the ketones (II) to give the 1‐aminopyrroles (III) and (VI).
ChemInform Abstract: New Azathiadiphosphetidines.
Authors: DONATH C. , WALLIS B. , MEISEL M. , LEIBNITZ P.
Published: May 2016

The 1:2 molar reaction of the betaine salt (I) with the prim. amines (II) leads to the pyridinium 1‐alkyl‐2‐alkylamino‐azathiadiphosphetidinethiolates (III) which react with MeI (IV) to give the corresponding methyl esters (V) and (VI).
ChemInform Abstract: Synthesis, Properties, and NMR Investigation of Phenylphosphonothioic Acid Bis(trimethylsilylamide) and 1,3‐Bis(trimethylsilyl)‐2,4‐diphenyl‐2,4‐dithioxo‐1,3,2λ5,4λ5‐dia# zadiphosphetidine.
Authors: DOSTAL K. , PRIHODA J. , STOKLASEK S. , LOUCKY J. , PINKAS J. , GROSSMANN G. , OHMS G.
Published: May 2016

The title compounds (III) and (IV) are obtained according to the scheme.
ChemInform Abstract: Synthesis and NMR Spectra of λ5‐Diphosphetes. Structure of 2,4‐Diphenyl‐1,1,3,3‐tetrakis(diethylamino)‐1λ5,3λ5‐diphosphete.
Authors: FLUCK E. , NEUMUELLER B. + , RIFFEL H.
Published: May 2016

The λ5‐diphosphetes (III) are synthesized according to the scheme.
ChemInform Abstract: Nitrogen‐ and Tellurium‐Containing Heterocycles. Part 3. Reactions of 2‐Phenylbenzotellurazole at the Heteroatoms.
Authors: SADEKOV I. D. , ABAKAROV G. M. , SHNEIDER A. A. , MINKIN V. I.
Published: May 2016

Reaction of the benzotellurazole (I) with halogens proceeds at the tellurium atom to give the dihalotellurazoles (II).
ChemInform Abstract: Pentadienyl‐Metal‐Phosphine Chemistry. Part 18. Mechanism of η1‐Pentadienyl Ligand Isomerization. First Structural Characterization of a 3‐η1‐Pentadienyl‐Metal Complex.
Authors: BLEEKE J. R. , EARL P. L.
Published: May 2016

The conversion of the cis‐η1‐pentadienyl ligand in (III) to its trans‐η1‐isomer (V) proceeds in two steps.
ChemInform Abstract: Formation of Fe‐Sn Bonds by the Reaction of Tris(trimethylstannyl)amine with Fe(CO)5 and Fe(CO)4CS; 13C‐, 17O‐, and 119Sn NMR Spectroscopic Studies.
Authors: PETZ W. , WRACKMEYER B. , STORCH W.
Published: May 2016

The reaction of (I) and (II) gives the known complex (III), in the analogous reaction with (IV), (V) is obtained.
ChemInform Abstract: Transition Metal‐Cyanocarbon Chemistry. Part 8. Cyano‐Substituted Buta‐1,3‐dienylidene Bridged Diiron Complexes from Unprecedented Cyanoalkyne Insertion into the Carbon‐Hydrogen Bond of a Bridging Alkenylidene Ligand.
Authors: ETIENNE M. , GUERCHAIS J. E.
Published: May 2016

The μ‐4‐cyanobuta‐1,3‐dienylidene complexes (III) and (V) are obtained as mixtures of Z and E isomers by the unprecedented formal insertion of the cyanoethynes (II) and (IV) into a vinylic C‐H bond of the μ‐ethylidene complexes (I).
ChemInform Abstract: Reversible and Diastereospecific Insertion of 2‐Acetamidoacrylic Methyl Ester into the Metal‐Hydrogen Function of Chiral Clusters.
Authors: MANI D. , SCHACHT H.‐T. , POWELL A. K. , VAHRENKAMP H.
Published: May 2016

The chiral hydrido metal clusters (I) react with the prochiral alanine precursor (II) by insertion into the M1‐H function and substitution of a CO ligand.
ChemInform Abstract: Interaction of Isocyanide with Transition‐Metal Complexes. Part 33. Low‐Valent Isocyanide Complexes and Clusters of Palladium and Platinum. Crystal Structure of Cyclic (Pt(C(=NR)N(R)C(=NR))(RNC)2) (R: 2,6‐Me2C6H3).
Authors: YAMAMOTO Y. , YAMAZAKI H.
Published: May 2016

Reduction of (Ia) with sodium amalgam in the presence of the isocyanide (II) gives the two clusters (IV) and (V) and the complexes (VI) and (VIIa).
ChemInform Abstract: Structure of a Non‐Planar Flavonol, 5,7,2′‐Trihydroxy‐3,6,8,4′,5′‐pentamethoxyflavone.
Authors: ABBOUD K. A. , SIMONSEN S. H. , MABRY T. J. , FANG N.
Published: May 2016

The rings A, B and C of a lot of flavones and flavonols show a high level of coplanarity.
ChemInform Abstract: New and Effective Routes to Fluoro Analogues of Aliphatic and Aromatic Amino Acids.
Authors: OJIMA I. , KATO K. , NAKAHASHI K. , FUCHIKAMI T. , FUJITA M.
Published: May 2016

Treatment of the trifluoromethylated aldehydes (I) and (VI) with acetamide (II) in the presence of carbon monoxide (III) and hydrogen, followed by acidic hydrolysis, gives the amino acids (V) or (VII).
ChemInform Abstract: Structural Studies of Mitomycins. Part 2. Structure of Mitomycin A Hemihydrate.
Authors: HIRAYAMA N. , SHIRAHATA K.
Published: May 2016

Mitomycins are effective antitumor antibiotics.
ChemInform Abstract: The Chemistry of Pseudomonic Acid. Part 10. Preparation of Heterocyclic Derivatives.
Authors: CRIMMIN M. J. , O'HANLON P. J. , ROGERS N. H. , WALKER G.
Published: May 2016

A large variety of normonyl heterocycles is prepared using the ketone (I) for introducing the normonyl residue.
ChemInform Abstract: Synthesis of Albidin (6‐Methoxy‐3‐methylisobenzofuran‐4,5‐dione) and (.+‐.)‐Curvulol ((.+‐.)‐1,3‐Dihydro‐6‐methoxy‐3‐methylisobenzofuran‐4,5‐diol).
Authors: TENNANT S. , WEGE D.
Published: May 2016

The red pigment albidin, a constituent of Penicillium albidum with strong antibiotic and fungistatic activity, is prepared in its racemic form (VIII) starting from the aldehyde (I) (readily available from vanillin).
ChemInform Abstract: Synthesis of Deepoxy‐4,5‐didehydromethylenomycin A and Methylenomycin A Methyl Esters.
Authors: MAHIDOL C. , THEBTARANONTH C. , THEBTARANONTH Y. , YENJAI C.
Published: May 2016

The anthracene adduct (I) reacts with the propionate anion (II) to form the triester (III).
ChemInform Abstract: Electronic Structure of Coinage Metal Clusters
Authors: BALASUBRAMANIAN K.
Published: May 2016

(recent experimental and theoretical works (MCSCF and MRSDCI) on small coinage metal (Cu, Ag, Au) clusters; 124 refs.
ChemInform Abstract: Hydrogen(Deuterium)‐Stabilized and Lithium‐Intercalated Erbium Monochloride: An X‐Ray Single‐Crystal and Neutron Powder Diffraction Study.
Authors: SCHLEID T. , MEYER G.
Published: May 2016

The single crystal XRD results for ErClHx (ZrCl‐type) and Li0.3ErClHx (ZrBr‐type) show that both compounds crystallize in the trigonal system, space group R3m with Z = 6. The neutron powder diffraction studies of ErClD0.7 and 7Li0.4ErClD0.6 confirm the XRD results.
ChemInform Abstract: Synthesis, Structure and Properties of Mn1.5Mo8O11, a Unique Structure Type Among Compounds Having Infinite Chains of trans‐Edge‐Shared Octahedral Cluster Units.
Authors: CARLSON C. D. , BROUGH L. F. , EDWARDS P. A. , MCCARLEY R. E.
Published: May 2016

Single phase Mn1.5Mo8O11 is obtained from the reaction of MnMoO4, MoO3, and Mo (9:10:29, sealed Mo‐tube, 1450 °C, 4 d).
ChemInform Abstract: Structural and Optical Properties of Hydrated Lanthanoid Uranyl Arsenates.
Authors: DORHOUT P. K. , SABEL D. M. , ELLIS A. B. , MARTINEZ‐LARA M. , BRUQUE‐GAMEZ S. , SANCHEZ‐REINA J. L. , MORENO‐REAL L.
Published: May 2016

Compounds of approximate composition Ln(UO2AsO4)3·xH2O (Ln: La, Ce‐Lu; x = 13‐16) are prepared by intercalation of Ln3+ into either HUO2AsO4·4 H2O or n‐butylammonium uranyl arsenate.
ChemInform Abstract: Antiferromagnetic‐to‐Ferromagnetic Transition in Metallic Tl1‐xKxCo2Se2 (0 ≤ x ≤ 1.0) with ThCr2Si2‐Type Structure.
Authors: HUAN G. , GREENBLATT M.
Published: May 2016

Solid solutions of Tl1‐xKxCo2Se2 (0 ≤ x ≤ 1.0) are prepared by solid state reactions of cobalt and potassium metal, TlSe, and Se (1.
ChemInform Abstract: The Corrosion Behavior of Silicon Carbide in 290 °C Water
Authors: HIRAYAMA H. , KAWAKUBO T. , GOTO A. , KANEKO T.
Published: May 2016

is studied as a function of pH and concentration of dissolved oxygen.
ChemInform Abstract: Selective Syntheses Using Cyclodextrins as Catalysts. Part 5. para‐Selective Hydroxymethylation of Phenol by Formaldehyde Using Hydroxypropyl Cyclodextrins.
Authors: KOMIYAMA M.
Published: May 2016

In the presence of 0.6 mol/dm3 of hydroxypropyl β‐cyclodextrin (degree of substitution 5.8) as cat., the rate constant for the formation of (II) is 16 times as large as that for (III).
ChemInform Abstract: Piezochemical Interpretation of (C···H···X) Hydrogen Transfer in Ene Reactions.
Authors: JENNER G. , BEN SALEM R. , EL'YANOV B. , GONIKBERG E. M.
Published: May 2016

Measurement of volumes of activation has provided mechanistic information about ene reactions involving C···H···X hydrogen transfer (X: O, C, N).
ChemInform Abstract: Aprotic Conjugate Addition Reactions of Lithiated Allylic Sulfoxides with Acyclic Enones: A Breakdown of the trans‐Decalyl Transition State.
Authors: HAYNES R. K. , KATSIFIS A. G. , KING L. M. , VONWILLER S. C.
Published: May 2016

It is known from earlier reports that the aprotic conjugate addition of lithiated allylic sulfoxides to five‐membered cyclic ketones proceeds in a highly stereoselective manner at C(3) of the allylic system.
ChemInform Abstract: Reaction of Ethylmagnesium Bromide with Carboxylic Esters in the Presence of Titanium Tetraisopropylate.
Authors: KULINKOVICH O. G. , SVIRIDOV S. V. , VASILEVSKII D. A. , PRITYTSKAYA T. S.
Published: May 2016

In the presence of equimolar amounts of Ti(OiPr)4 the reaction between the carboxylic esters (I) and EtMgBr (II) affords the 1‐substituted cyclopropanols (III) in high yields.
ChemInform Abstract: Novel One‐Step Procedure for the Synthesis of Polysubstituted Cyclopent‐2‐en‐1‐ones by the Reaction of 5,5‐Dimethoxytetrachlorocyclopentadiene with Allyl‐Type Anions.
Authors: ISMAILOV S. A.
Published: May 2016

The novel procedure specified in the title proceeds under very mild conditions.
ChemInform Abstract: Ketone‐Ketone Condensations with Participation of Mesityl Oxide.
Authors: SOSNOVSKIKH V. YA. , OVSYANNIKOV I. S.
Published: May 2016

In the presence of N‐ethylanilinomagnesium bromide the reaction between mesityl oxide (I) and acetophenone (IIa), the alkyl aryl ketones (IIb) and (IIc) and the aryl phenyl ketones (IId) yields the β‐ketols (IIIa)‐(IIId).
ChemInform Abstract: Dephosphorylation of 1‐Substituted Perfluoro‐1‐alkenyl Phosphates with Diisobutylaluminum Hydride. A New Highly Efficient Method for Generating Perfluoroalkyl Ketone Aluminum(III) Enolates.
Authors: ISHIHARA T. , YAMAGUCHI K. , KUROBOSHI M.
Published: May 2016

The fluorinated enol phosphates (I), prepared from ketones and sodium diethyl phosphite, react with diisobutylaluminum hydride (II) to form the aluminum enolates (III).