bluuebunny/crossref_metadata_2025 huggingface dataset:
MONOGRÁFICO: La bioeconomía circular, clave para el desarrollo territorial sostenible
Authors: Cátedra Cerón Mar , Capote Carmen , Lasarte López Jesús , Gurria Albusac Patricia , M’barek Robert , Ortiz Gutiérrez Esther , Argüelles Hernández Milagros , Sayadi Gmada Samir
Published: December 2024

La bioeconomía circular es una oportunidad para el desarrollo territorial y debe tener un enfoque participativo y transversal, involucrando a todos los actores, políticas y estrategias regionales. En este contexto, se celebró el Foro de Bioeconomía Circular en Sevilla, Andalucía, el 21 de noviembre de 2023. En este evento se dieron cita representantes de las administraciones públicas, responsables institucionales, entidades del ámbito empresarial y de la academia, así como representantes de la sociedad civil y responsables de proyectos de interés en bioeconomía, tanto a nivel regional y nacional como europeo y centroamericano. Con más de trescientos cincuenta participantes, el evento permitió debatir y presentar el avance, situación actual y perspectivas de la bioeconomía circular en los territorios rurales. En el presente artículo se abordan los principales aspectos analizados, como políticas y estrategias de bioeconomía de las diferentes regiones participantes; debilidades, amenazas, fortalezas y oportunidades de la bioeconomía circular; casos de éxito y prácticas desarrolladas por diversas entidades; retos a los que se enfrenta la bioeconomía circular; mercados y modelos de negocio y de consumo; importancia de la cooperación entre los diversos actores de la cuádruple hélice (sector público, sector privado, sector académico y científico y sociedad civil) con un enfoque territorial; sensibilización de la sociedad en cuanto a la demanda y concienciación de un modelo basado en la bioeconomía circular; importancia de la formación y educación en bioeconomía circular y papel de la I+D+i.
EDITORIAL
Authors: Cátedra Cerón Mar
Published: December 2024

Editorial del Nº5 de la Revista C3-Bioeconomy realizado por la Consejera Técnica de la Secretaría General de Agricultura, Ganadería y Alimentación de la Junta de Andalucía, Mar Cátedra Cerón
THE FACTORS CAUSING CONSUMER BEHAVIOR: ASYMMETRIC CAUSALITY AND CLUSTER ANALYSIS FOR EU COUNTRIES THROUGH CONSUMER CONFIDENCE INDEX
Authors: Engeloğlu Özgür , Yurdakul Funda
Published: December 2024

The main purpose of this study is to determine the factors affecting consumer behavior for 27 European Union (EU) countries and to analyze which country consumers have similar behavior patterns. The dataset covers the period from 2012M01 to 2019M12. First, we used asymmetric causality tests to examine the relationships between consumer confidence index and the variables that influence it. Asymmetric causality tests consider the effect of asymmetric information, assuming that the response of units to positive and negative shocks may differ. In this way, it may occur some confidential information that cannot be detected in symmetric tests, through the asymmetric tests. Second, we applied the cluster analysis to outputs of asymmetric causality tests. We found that the indicator that has the most impact on consumer confidence index is stock market indices. Also, unemployment rate, consumer price index, and election periods are influencing consumer confidence index significantly. As a result of the cluster analysis, we detected the existence of five different country groups. Some of these groups included countries with similar geographical conditions and similar cultures.
Improved Deep Perceptual Hashing Algorithm (IDP-HA), Information Retrieval System, Microsoft Common Objects In Context (MS COCO), Remote Cloud Computing, Computer science, information systems
Authors: Ismael Othman Atta , Hassan Israa Fars Hassan
Published: December 2024

يمكن أن يعزى نمو استرجاع المعلومات والخدمات المرتبطة بها إلى التقدم التقني. وفي الوقت نفسه، تتأثر الطرق التقليدية لاسترجاع المعلومات بقيود الأداء والدقة وقابلية التوسع. يعد نظام استرجاع المعلومات للحوسبة السحابية البعيدة الذي يعتمد على خوارزمية التجزئة الإدراكية العميقة المحسنة (IDP-HA) أحد الحلول التي تم تطويرها لحل هذه القيود. تُستخدم الأنظمة على نطاق واسع نظرًا لقدرتها على التعرف على الأنماط المعقدة في البيانات. لا تزال دقة قياس تشابه المعلومات غير متوفرة بسبب التعقيد الكامن في البيانات وطرق القياس. يستخدم أسلوب التجزئة الإدراكي العميق أطر عمل الشبكة العصبية العميقة (DNN) لاستخراج الميزات الهرمية من الصور المدخلة من مجموعة بيانات Microsoft Common Objects in context (MS COCO). يعد مرشح Gaussian (GF) أداة تستخدم في المعالجة المسبقة للصور الفردية لرؤى الكمبيوتر المختلفة. وبعد ذلك، تقوم هذه الطريقة بإنشاء أرقام التجزئة الرقمية عن طريق وصف العناصر المرئية للصور باستخدام آلية العتبة. هدفها الأساسي هو تحسين مقياس التشابه للحفاظ على التشابه الإدراكي وضمان تشابه رموز التجزئة للصور القابلة للمقارنة بصريًا. يتم تقليل استخدام الذاكرة باستخدام دالة التجزئة كخطوة أولى في إنشاء اتصال بين قاعدة البيانات والاستعلام. يجد هذا النهج تطبيقات في أنظمة استرجاع الصور القائمة على المحتوى، واسترجاع الصور، وتجميع الصور، واكتشاف النسخ. وبشكل عام، فهو يوفر إطارًا قويًا لإنتاج تمثيلات صور مدمجة وذات أهمية دلالية. تم تحسين IDP-HA للحوسبة السحابية عن بعد لتعزيز متوسط الاستدعاء ومتوسط الدقة ومتوسط قياس F1 ومتوسط توقيت الاستعلام لعمليات استرداد البيانات. تعمل هذه الطريقة على تقليل زمن الوصول وزيادة كفاءة النظام عن طريق إنشاء تمثيلات ثنائية مدمجة لبيانات الوسائط المتعددة. يمكن أن يكون الاسترجاع القائم على التشابه البصري موثوقًا وطبيعيًا حيث يتم الحفاظ على التشابه الإدراكي.
Stationary Distribution of Stochastic SEIRS Epidemic Model with Saturated Incidence Rate and Saturated Treatment Function
Authors: S Saravanan , C Monica
Published: December 2024

يهدف هذا البحث إلى تعزيز وتوسيع النموذج الرياضي الذي يحكم وباء SEIRS العشوائي الديناميكي (المعرض والمكشوف والمعدي والمعافى). يدمج هذا النموذج المعقد مكونات حاسمة، بما في ذلك معدل الإصابة المشبع و دالة العلاج المشبعة، والتي تعتبر أساسية في تشكيل ديناميكيات الوباء. الهدف هو استكشاف وجود و وحدانية الحل العالمي الإيجابي من خلال تطبيق وظيفة Lyapunov المصممة بدقة، مما يسهل إجراء تحليل أكثر عمقا لتعقيدات الأنظمة. يمكّننا هذا الإطار التحليلي من الكشف عن التفاعلات بين انتقال المرض وديناميكيات العلاج والتأثيرات العشوائية. ضمن هذا الإطار النظري، يفترض أن الاستجابة للعلاج تتناسب طرديا مع عدد الأفراد المصابين طالما بقيت حالات الإصابة داخل نظام الرعاية الصحية. يكمن أحد الجوانب الرئيسية لمساهمتنا في تحديد رقم التكاثر الأساسي العشوائي  باعتباره عتبة حرجة تحدد مسار الوباء. في ظل الظروف التي تتميز بمستويات ضوضاء منخفضة و ، فإنه يحدد المتطلبات الأساسية لظهور توزيع ثابت مريح، ويقدم نظرة ثاقبة للاتجاهات المحتملة طويلة المدى في انتشار المرض. وعلى العكس من ذلك، في السيناريوهات التي تتميز بكثافة الضوضاء العالية ، يلقي تحليلنا الضوء على الاستئصال الحتمي للمرض. ولزيادة تعزيز الأسس النظرية، يدمج بحثنا عمليات محاكاة رقمية واسعة النطاق. لا تؤكد عمليات المحاكاة هذه صحة النتائج النظرية التي توصلنا إليها فحسب، بل توفر أيضًا تصورًا ديناميكيًا لآثار النموذج. تساهم هذه المنهجية المزدوجة، التي تجمع بين الفحص النظري الدقيق وعمليات المحاكاة العملية، في فهم دقيق لدور العشوائية في تشكيل ديناميكيات الوباء.
Detection Lung Nodules Using Medical CT Images Based on Deep learning techniques
Authors: Mohammed Ali Abdulwahhab , Abdulwahhab Ali H. , Ibraheem Ibraheem Kasim
Published: December 2024

يعد اكتشاف سرطان عقيدات الرئة تحديًا طبيًا بالغ الأهمية ومعقدًا. يمكن أن يؤدي الدقة في اكتشاف عقيدات الرئة إلى تحسين تشخيص المريض ورعايته بشكل كبير. يتمثل التحدي الرئيسي في تطوير طريقة كشف يمكنها التمييز بدقة بين العقيدات الحميدة والخبيثة وتعمل بشكل فعال في ظل ظروف التصوير المختلفة. إن تطوير التكنولوجيا والاستثمار في تقنيات التعلم العميق في المجال الطبي يجعل من السهل استخدام التصوير المقطعي بالإصدار البوزيتروني (PET) والتصوير المقطعي المحوسب (CT). وبالتالي، تقدم هذه الورقة الكشف عن سرطان الرئة عن طريق تصفية صورة PET-CT، والحصول على منطقة الرئة ذات الاهتمام (ROI)، والتدريب باستخدام نماذج التعلم العميق للشبكة العصبية التلافيفية (CNN) للدفاع عن موقع العقيدات. تتكون مجموعة البيانات المحدودة من 220 حالة مع 560 عقيدة مع وحدات هاونسفيلد الثابتة (HU) المستخدمة لزيادة سرعة التدريب وحفظ البيانات. تتضمن النماذج المدربة CNN وDCNN و3DCNN وVGG 19 وResNet 18 وInception V1 وInception-ResNet للكشف عن عقيدات الرئة. تُظهر التجربة أن التدريب عالي السرعة باستخدام VGG 19 يتفوق على بقية التعلم العميق، حيث يحقق الدقة والدقة والخصوصية والحساسية ودرجة F1 وIoU ومعدل FP بالتقسيم القياسي؛ 98.65 ± 0.22 و98.80 ± 0.15 و98.70 ± 0.20 و98.55 ± 0.18 و98.60 ± 0.16 و0.94 ± 0.03 و1.05 ± 0.22 على التوالي. علاوة على ذلك، تظهر نتائج التجربة معدل خطأ إجمالي إلى جانب التقسيم القياسي بين ± 0.04 إلى ± 0.54 موزعة على شروط الحساب.
Analysis of Thermal Conductivity, Surface Roughness, and Hardness of Carbon Nanotube-Reinforced Three-Dimensional Printed Acrylic Resin
Authors: Khalid Ranin Raad , Fatalla Abdalbseet A Fatalla , AL-Rawas Matheel , Johari Yanti , Beh Yew Hin , Abdullah Johari Yap
Published: December 2024

إن مجال طب الأسنان في تطور مستمر، خاصة مع تكنولوجيا الطباعة ثلاثية الأبعاد. تهدف هذه الدراسة إلى تحليل كيفية تأثير قواعد أطقم الأسنان المصنوعة من مادة الراتنج ثلاثية الأبعاد على التوصيل الحراري، وخشونة السطح، وصلابة السطح عند إضافة أنابيب الكربون النانوية (CNTs) بنسب وزنية مختلفة. تمت إضافة الأنابيب النانوية الكربونية إلى راتينج أكريليك قاعدة طقم الأسنان المطبوع ثلاثي الأبعاد. تم تقسيم العينات إلى ثلاث مجموعات؛ 0.5% و0.7% من الأنابيب النانوية الكربونية بالوزن ومجموعة مراقبة أخرى لا تحتوي على الأنابيب النانوية الكربونية المضافة. خضعت جميع العينات لاختبارات التوصيل الحراري وخشونة السطح وصلابة السطح. تم إجراء تحويلات فورييه للتحليل الطيفي للأشعة تحت الحمراء وتحليلات المجهر الإلكتروني لمسح الانبعاثات الميدانية، وتم تحليل البيانات عن طريق تحليل التباين (ANOVA) أحادي الاتجاه واختبارات المقارنة المتعددة. أدت إضافة الأنابيب النانوية الكربونية إلى راتينج قاعدة طقم الأسنان المطبوع ثلاثي الأبعاد إلى تحسين صلابة السطح والتوصيل الحراري مقارنة بمجموعة التحكم ويرتبط ذلك بتركيز الأنابيب النانوية الكربونية المضافة. ومع ذلك، زادت خشونة السطح مع زيادة الأنابيب النانوية الكربونية المضافة إلى الراتنج. تعمل إضافة الأنابيب النانوية الكربونية إلى راتينج قاعدة طقم الأسنان المطبوع ثلاثي الأبعاد على تحسين السلوك الميكانيكي للمادة، وخاصة التوصيل الحراري وصلابة السطح، ولكن ليس خشونة السطح. لذلك يجب توخي الحذر عند اختيار التركيز المناسب من الأنابيب النانوية الكربونية المراد إضافتها إلى راتينج الطباعة ثلاثية الأبعاد في تحسين خصائص المواد
Loss of ARID1A leads to a cold tumor phenotype via suppression of IFNγ signaling
Authors: Freeman Kevin , Watson Pamela , DeVaux Chelsea
Published: December 2024

The collapse of inflammatory signaling that recruits cytotoxic immune cells to the tumor microenvironment contributes to the immunologically cold tumor phenotype in neuroblastoma (NB) and is a barrier to NB immunotherapy. Multiple studies have reported that MYCN amplification, a trait of high-risk NB, correlates with a loss of inflammatory signaling; but MYCN also correlates with 1p36 deletions in NB where the SWI/SNF chromatin remodeling complex subunit ARID1A (1p36.11) is located. ARID1A is known to support inflammatory signaling in adult cancers but its role in NB inflammatory signaling is unexplored. We find MYCN overexpression causes a stronger and ARID1A knockdown causes a weaker inflammatory response to interferon-gamma (IFNγ). ARID1A silencing reduces IFNγ induced gene signatures for the transcription factor interferon response factor 1 (IRF1). We found ARID1A is a functional interactor of IRF1 by co-immunoprecipitation studies, and ARID1A silencing causes loss of activating chromatin marks at the IRF1 target gene CXCL10. We model that IRF1 uses ARID1A containing SWI/SNF to promote IRF1’s target genes in response to IFNγ. This work finds that ARID1A is a critical regulator of inflammatory signaling in NB and provides rationale for testing immune therapies in MYCN amplified NB that are effective in adult ARID1A mutated cancers.
Community-Engaged Research on Water Quality Analysis and Environmental Risk Zone (ERZ) Mapping using GIS and Neuro- Fuzzy Models in Ramanathapuram District, Tamil Nadu, India
Authors: A Stanley Raj , Angelena J. P. , Roy Ronald Win , Pious Joseph , Jobisha J. , Fredrick A. , Selvan C. Tamil , Oliver Hudson
Published: December 2024

Water, a basic amenity and universal solvent, is utilized by the population. Physicochemical analysis of the Ramanathapuram district of Tamil Nadu was performed to evaluate its suitability for potable purposes. The quality of groundwater was determined through the analysis of pH, electrical conductivity, sulfate content, nitrate content, total hardness, calcium content, magnesium content, sodium content, and total dissolved solids. The results were computed and compared with WHO and BIS water quality standards. In several regions, the permissible limits of electrical conductivity, sulfate, nitrate, magnesium, total hardness, and other parameters were exceeded. High concentrations of these parameters may be attributed to urbanization, saline water intrusion, and the influence of sewage. The obtained results suggest the need for regular monitoring of groundwater quality in this study area to prevent further contamination. A neurofuzzy weighted algorithm was applied to assign weights to each geochemical parameter, culminating in an environmental risk zone assessment. This emphasizes the critical need for ongoing evaluation and proactive measures to ensure the safety and sustainability of groundwater resources in the region. The current research is validated with the field data collected from local community people of Ramanathapuram district. This research portraits the current scenario of groundwater in the study area and it necessitates the government to take measures, awareness and policies related to the improvement of groundwater quality.
Why do rural residents in China withdraw from the health insurance system? —A Qualitative Study Based on Y County in S Province, China
Authors: Zuo Ying , Yang Guang , Cheng Haoxuan , Zhang Lufa
Published: December 2024

Background:Since the 2009 healthcare reform, the Chinese government has been committed to establishing a universal healthcare system. This study aims to investigate the complex reasons behind the decision of rural residents in China to forgo participation in the medical insurance system by examining causal relationships and interactions.
Methods: This study employs content analysis, conducting in-depth interviews with 42 stakeholders, including government administration departments, tax departments, medical insurance departments, village committees, and residents who have not enrolled in the medical insurance.
Results: The study finds that the primary reasons for rural residents withdrawing from medical insurance are fourfold: heavy economic burdens, unfair design of the medical insurance system, failure of conventional mobilization strategies, and cognitive biases fostered by the internet.
Conclusion: The decision of rural residents in China to withdraw from medical insurance is influenced not only by economic factors but also by the design of the system and various aspects of rural governance. In the future, the Chinese government should optimize the design of the medical insurance system, adopt more flexible mobilization and persuasion strategies, and strengthen the control of negative internet rhetoric to stimulate enthusiasm for participation in medical insurance among rural residents, thereby advancing the universal health strategy.
Preventing Preeclampsia via the targeted Inhibition of Procoagulant Platelets
Authors: Chu Yaxin , Su Yang , Yang Jing , Guo Han , Zhang Yuncong , Guo Wanwan , Qiao Rui
Published: December 2024

Preeclampsia (PE) is a placenta-mediated thrombotic-inflammatory syndrome. Procoagulant platelets are the main source of platelet microparticles (PMPs), which can result in both pro-inflammatory and pro-thrombotic effects. Therefore, we hypothesized that targeted inhibition of procoagulant platelets would prevent PE via the reduction of PMPs generation. The procoagulant platelet levels in 49 healthy pregnant women and 39 pregnant women with PE were measured and compared. High-performance liquid chromatography coupled with mass spectrometry (LC–MS/MS) was used to investigate the differential proteomes of the platelet proteins isolated from 6 healthy pregnant women and 6 pregnant women with PE. Recombinant protein CD39-Diannexin was constructed for the targeted inhibition of procoagulant platelets. A PE mouse model was developed to investigate whether targeted inhibition of procoagulant platelets could prevent PE. PE patients showed elevated levels of procoagulant platelets and platelet microparticle generation; their platelet proteomics revealed that the proteins involved in complement, coagulation, and inflammation responses were downregulated. Recombinant protein CD39-Diannexin can target the inhibition of procoagulant platelet function both ex vivo and in vivo. This can prevent the PE-like phenotype, characterized by decreased blood pressure, protein/creatine (P/C) ratio, soluble fms-like tyrosine kinase (sFlt-1), decreased pregnancy failure, and reduced placenta inflammasome activation. To conclude, procoagulant platelets are involved in the mechanism underlying PE and the recombinant protein CD39-Diannexin may help prevent PE via the targeted inhibition of procoagulant platelets.
Quantum Simulation of Spin-Boson Models with Structured Bath
Authors: Kim Jungsang , Sun Ke , Kang Mingyu , Nuomin Hanggai , Schwartz George , Brown Kenneth , Beratan David
Published: December 2024

The spin-boson model, involving spins interacting with a bath of quantum harmonic oscillators, is a widely used representation of open quantum systems that describe many dissipative processes in physical, chemical and biological systems. Trapped ions present an ideal platform for simulating the quantum dynamics of such models, by accessing both the high-quality internal qubit states and the motional modes of the ions for spins and bosons, respectively. We demonstrate a fully programmable method to simulate dissipative dynamics of spin-boson models using a chain of trapped ions, where the initial temperature and the spectral densities of the boson bath are engineered by controlling the state of the motional modes and their coupling with qubit states. Our method provides a versatile and
precise experimental tool for studying open quantum systems.
Unmasking rifampicin mono-resistance in tuberculosis patients in Cross River State, Nigeria
Authors: Ochang Ernest Afu , Udoh Ubong Aniefiok , Otu Akaninyene Asuquo , Uket Atana , Ibe Chibuke , Moore David A. J.
Published: December 2024

Background
Current tuberculosis management algorithm in Nigeria recommends commencement of multi-drug resistant tuberculosis (MDR-TB) treatment on rifampicin resistance detection, following XpertMTB/Rif (Genexpert) test and subsequent re-direction of therapy after phenotypic drug susceptibility testing. With the current dearth of phenotypic drug susceptibility testing facilities in Nigeria, for quick and precise identification of drug resistant tuberculosis, several rifampicin mono-resistant tuberculosis patients may be inappropriately placed on toxic second line drugs used for MDR-TB treatment for prolonged periods before susceptibility results are available.
Method
XpertMTB/Rif were performed on a total of 3,580 patient samples from 10 sites across Cross River State, Nigeria as a prospective cross sectional study. Rifampicin resistant specimens were reprocessed and cultured on Lowenstein Jensen medium. Indirect susceptibility testing following the microscopic observation drug susceptibility technique was performed using Rifampicin (1 µg/ml), Isoniazid (0.4 µg/ml), Flouroquinolone (Ofloxacin-1.0 µg), Capreomycin (2.5 µg/ml), Amikacin (2 µg/ml) and Kanamycin (5.0 µg/ml).
Result
Mycobacterium tuberculosis was detected in 21.3% (763) of the 3,580 presumptive tuberculosis cases recruited, of which 4.6% (35/763) were resistant to rifampicin. Culture yielded isolates from 89.6% (31/35) of these rifampicin resistant cases while susceptibility testing using first and second line antimicrobials, revealed 32.2% (10/31) and 64.5% (20/31) rifampicin mono-resistant and MDR-TB respectively. When categorized into treatment groups, 25.7% (27/105) and 1.2% (8/658) of patients with rifampicin resistance belonged to retreatment and naïve patient groups respectively. There was no correlation between rifampicin mono-resistant and MDR-TB with gender (χ2 = 0.793, P = 0.308) or HIV status (χ2 = 0.416, P = 0.398). Patients who presented with first line treatment failure were most likely to have MDR-TB (χ2 = 9.121, P = 0.028).
Conclusion
With the current MDR-TB treatment algorithm and lack of programmatic support for drug susceptibility testing, a significant number of patients with rifampicin mono-resistance are treated as MDR-TB for prolonged periods. More programmatic support and scale up of simpler susceptibility techniques are required.
Impact of COVID-19 infection on thyroid functions
Authors: hamed hanaa S , khodary Reda El , Lotfy Samah Mohamed , Sakr Maha Mahmoud Hamed , Saied Mohammad Walaa
Published: December 2024

Impact of Covid-19 infection on thyroid functions
Background:
The 2019 coronavirus illness (COVID-19) has caused significant disruption on a worldwide scale. With several recent studies observing the rise of thyroid problems in afflicted individuals, the influence of COVID-19 on thyroid function is receiving more attention.
This study aims to determine the prevalence of thyroid dysfunction in COVID patients.
Methods: We evaluated thyroid function tests (TFTs) in 129 patients who were hospitalized to Zagazig University Hospitals with confirmed COVID-19 infection. Patients with pre-existing thyroid conditions or those on medications influencing (TFTs) were excluded. Serum levels of free thyroxine (FT4), thyrotropin (TSH), and free triiodothyronine (FT3) were measured on the first day of admission, followed by follow-up TFTs within the first six months, one year, and two years after discharge.
Results: We included 129 patients aged between 22 and 70 years, with 38 (29.5%) identified as male and 91 (70.5%) as female. Upon admission, (TFTs) were normal in 14.9% of patients. The findings also revealed 13.2% with subclinical hypothyroidism, 32.6% with subclinical hyperthyroidism, 6.2% with hypothyroidism, and 37.2% with hyperthyroidism. Two years after discharge, only 43.4% had normal TFTs, while 10.1% were being treated for hypothyroidism and 46.5% for hyperthyroidism.
Conclusion: This study emphasizes the complex interplay between COVID-19, thyroid function, and vaccination status. The results indicate that thyroid dysfunction specifically hyperthyroidism, subclinical hyperthyroidism, hypothyroidism, or subclinical hypothyroidism might be a frequent outcome for patients recovering from COVID-19, particularly in those who experienced more severe cases.
Disseminated nocardiosis in immunocompromised patient manifesting with lower extremity gangrene: A case report
Authors: Yohannes Kidus Geabriel , Kassa Nibretu Bekele , Tesso Zerubabel Girma , digga Abubeker mahammud
Published: December 2024

Introduction
Nocardia is an obligate aerobic actinomycetes in the genus Nocardia that exist throughout the world as soil and dust saprotrophs. It is uncommon gram-positive opportunistic bacterial infection that affects patients with impaired immune systems, solid-organ transplant recipients (SOTRs), and patients with hematologic malignancies.
Case presentation
Here we present a 6 years old male child with protein energy malnutrition and disseminated nocardiosis involving the lung and the soft tissue which later led to wet gangrene and amputation here we will be describing the various predisposing conditions alongside the clinical manifestation, the diagnostic workup, and the treatment course of disseminated nocardiosis.
Discussion
This case is being reported to emphasize the unusual clinical presentation of a unique infection that can resemble metastatic disease in the lungs and soft tissue. This similarity has led to challenges in diagnosing the infection and initiating early treatment, resulting in potential long-term consequences.
Evaluation of Community Health Service Center Training Base by Shanghai Hospice Care Competent Nurse Trainees: A Qualitative Study
Authors: Huang Yanjun , Wang Gan , Li Xinyu , Tang Yuezhong , Yu Zhijie , Chen Wen
Published: December 2024

Background: Enhancing the training of competent nurses in hospice care helps improve the quality of life for end-of-life care patients. This study aims to improve the effectiveness and quality of the training by exploring the attitudes of trained nurses in community health service centers towards the content and methods of the program.
Methods: We conducted semi-structured interviews with 15 eligible nurses specializing in hospice care from seven administrative districts in Shanghai between September and November 2024, using Colaizzi 7 method for analysis.
Results: The structure of the interview mainly revolves 4 topics, which are: Operational and Personalized Deficiencies in Course Content, Hospice Care Concept, Training Environment and Facilities, and Difficulties in Training Transfer for Hospice Care. The interviewee highlighted that while the project is practical and enhances professional competence and life values, it faces challenges in areas such as promotion opportunities, motivation mechanisms, implementation of humanistic care, nurses' willingness to learn about hospice care, salary adjustments, public awareness of hospice care, outpatient resource constraints, and the inclusion of emergency end-of-life care. These issues need to be addressed for improvement.
Conclusions: This study delves into the perspectives and feedback of hospice care nursing trainees on the current training programs, offering insights into enhancing and optimizing end-of-life care training projects by analyzing the strengths and areas for improvement in teaching content, scheduling, and philosophies. The findings support driving improvements in end-of-life care-related programs, including curriculum optimization, skill enhancement, expanded training scope, and ongoing public education.
Unlocking Ultra-stable Li5FeO4 in Air: Key Advances and Practical Demonstrations
Authors: Su Xin , Liu Canshang , Zhang Hao , Zhou Weiwei , Tian Xu , Zhang Tiantian , Niu Sicheng , Cao Minglei , Wang Qin , Lv Fei , Peng Tangping , Tao Lijuan , Rang Xiaodong , Chen Zhicheng
Published: December 2024

Li5FeO4 (LFO) holds great promise as a cathode pre-lithiation additive for enhancing the energy density of lithium-ion batteries. However, its significant air instability poses a formidable barrier to commercialization. In this study, we have developed an exceptionally effective “pitch-enabled carbon encapsulation” strategy to engineer ultra-stable LFO. By leveraging the meltability of pitch, a compact carbon coating can be formed on LFO (LFO@C), enabling it to retain a substantial capacity of 745.1 mAh/g even after 72 hours of exposure to air with 20% relative humidity (RH). Notably, this retained capacity after 72 hours constitutes 92.6% of its initial capacity and 85.9% of its theoretical maximum, representing the best air stability reported for LFO to date. In contrast, pure LFO rapidly declines to just 14.3% of its initial capacity within 4 hours under the same conditions. Beyond enhancing air stability, the carbon coating also improves LFO's specific capacity, rate capability, and cycling stability. To demonstrate its practical application, we assembled a pouch-type full cell on an industrial pilot line, accompanied by comprehensive failure analyses. The results indicate that the incorporation of LFO@C boosts the pouch cell's energy density by 13.7%. We believe that this work will significantly accelerate the real-world implementation of LFO.
The effect of composite cement-based materials on the heat loss of geothermal wellbores
Authors: Wei Kai , Wang Ao , Wu Desheng , Chen Hao , Liu Yulong
Published: December 2024

Geothermal energy, as a widely distributed, highly potential, stable, and reliable non-carbon-based clean renewable energy source, is crucial for energy transition and low-carbon development. Geothermal wells are the primary technical means for extracting geothermal energy. Geothermal wells, the core technology in geothermal energy development, consist of a multilayer composite system comprising casing, cement sheath, and formations, with a complex heat transfer process. This paper establishes a heat transfer model for the casing-cement-formation combination system and a thermal conductivity evaluation model for cementitious composites. Using numerical simulations, it analyzes the impact of sensitive factors, including fluid flow, thermal physical parameters of casing and cement sheath, and thermal properties of cement-based composites, on the heat extraction power of geothermal wells. The results indicate that the thermal conductivity of the cement sheath significantly influences the heat extraction power. Adding thermal insulation materials such as glass beads, slag microspheres, and aerogel particles to the cement sheath can effectively reduce its thermal conductivity, with aerogel particles being the most effective, reducing the thermal conductivity by approximately 30%. The models and findings in this study provide theoretical support and technical guidance for optimizing geothermal well design and improving geothermal energy development efficiency, contributing to the efficient utilization of geothermal energy.
PuMA: PubMed Gene-/Cell type-Relation Atlas
Authors: Bickmann Lucas , Sandmann Sarah , Walter Carolin , Varghese Julian
Published: December 2024

Rapid extraction and visualization of cell-specific gene expression is important for automatic cell type annotation, e.g. in single cell analysis. There is an emerging field in which tools such as curated databases or Machine Learning methods are used to support cell type annotation. However, complementing approaches to efficiently incorporate latest knowledge of free-text articles from literature databases, such as PubMed are understudied.This work introduces the PubMed Gene/Cell type-Relation Atlas (PuMA) which provides a local, easy-to-use web-interface to facilitate automatic cell type annotation. It utilizes a pretrained large language model in order to extract gene and cell type concepts from PubMed and links biomedical ontologies to suggest gene to cell type relations. It includes a search tool for genes and cells, additionally providing an interactive graph visualization for exploring cross-relations. Each result is fully traceable by linking the relevant PubMed articles. This work enables researchers to analyse and automatize cell type annotation based on PubMed articles. It complements manual curated marker gene databases and enables interactive visualizations. The software framework is freely available and enables regular article imports for incremental knowledge updates.GitLab: https://imigitlab.uni-muenster.de/published/PuMA/ Website: https://puma.uni-muenster.de
Durability Performance of Opc and Lc 3 -50 Concrete Containing Lightweight Aggregates
Authors: Hussain Syed Muhammad Fahad , Ayub Tehmina , Jamil Tariq , Khan Asad -ur-Rehman
Published: December 2024

This study investigates the durability properties of OPC and LC3-50 concretes containing shale as lightweight coarse aggregates acquired from the Balochistan Province of Pakistan for structural concrete in comparison to natural coarse aggregates. The physical properties of shale aggregates were initially assessed by performing crushing value, absorption, Impact value tests and specific gravity. In this study, two replacements for lightweight aggregate (0% and 100%) were investigated in OPC and LC3-50 concretes, which showed that the use of 100% lightweight in OPC and LC3-50-based concretes reduced compressive strength and splitting tensile strength by 60–65% and 25–30% in comparison to natural coarse aggregates without exposure to CO2. The reduction in the compressive and splitting tensile strengths due to CO2 exposure was more OPC than LC3-50 concrete due to dense microstructure, which is also evident by the permeability results. The effect of CO2 in reducing compressive and splitting tensile strengths at later ages (i.e. 270 and 365 days) becomes less than 90 and 180 days. The pull-out strength of OPC and LC3-50 concretes is almost similar at 7 and 28 days; however, the 28-day pull-out strength was observed to be 3 times higher than 7 days. Similarly, the permeability of LC3-50 concrete is better than OPC. Therefore, it can be concluded that LC3-50 in concrete improves durability and can be suitably used with 100% lightweight.
The diversity pattern of soil bacteria in the rhizosphere of different plants in mountain ecosystems
Authors: Yasen Maryamgul , Li Mingyuan , Wang Jilian
Published: December 2024

Research on the composition and diversity of rhizosphere microbial communities of different plant species can help to identify important microbial functional groups or functional potentials, which is of great significance for vegetation restoration and ecological reconstruction. To provide scientific basis for the management of mountain ecosystem, the diversity pattern of rhizosphere bacterial community was investigated using 16S rRNA high-throughput sequencing method among different host plants (Cirsium japonicum, Artemisia annua, Descurainia sophia, Lepidium apetalum, Phlomis umbrosa, and Carum carvi) in Tomur Peak National Nature Reserve, China. The results showed that the richness and diversity of rhizosphere bacteria were highest in Descurainia sophia, and lowest in Lepidium apetalum. Proteobacteria, Acidobacteriota, and Actinobacteria were the common dominant phyla, and Sphingomonas was the predominant genera. Furthermore, there were some specific genera in different plants. The relative abundance of non-dominant genera varied among the plant species. Canonical correspondence analysis indicated that available (AK), total phosphorus (TP), total potassium (TK), and soil organic matter (SOM) were the main drivers of bacterial community structure. Based on PICRUSt functional prediction, the bacterial communities in all samples encompass six primary metabolic pathways and 47 secondary metabolic pathways. The major secondary metabolic pathways (with a relative abundance of functional gene sequences > 3%) include 15 categories. Co-occurrence network analysis revealed differences in bacterial composition and interactions among different modules, with rhizosphere microorganisms of different plants exhibiting distinct functional advantages. This study elucidates the distribution patterns of rhizosphere microbial community diversity in mountain ecosystems, which provides theoretical guidance for the ecological protection of mountain soil based on the microbiome.
Agronomic responses of selected improved sorghum [Sorghum bicolor (L.) Moench] varieties to scheduled water stress
Authors: James Fadeyi Olasupo
Published: December 2024

The 13th sustainable development goal emphasises urgent action to combat climate change and its impacts; in this context, continuous evaluation of drought tolerance traits in crops with high climate-smart potential is imperative. The agronomic responses of three improved sorghum varieties (SAMSORG 44, SAMSORG 47, SAMSORG 48) under severe water stress conditions were investigated in a screen house study in 2022 (August–December) as a 3 × 3 factorial experiment in plastic pots arranged in a completely randomized design (CRD) with three replications. Three soil moisture stress levels [well-watered (WW), moderately water-stressed (MWS) and severely water-stressed (SWS) conditions] corresponding to 100, 50 and 25%, respectively, of fractional soil available water (FSAW) determined gravimetrically were imposed at 21 days after sowing (vegetative) and at 50% flowering (reproductive) for 2 weeks. Agronomic (phenological, growth, yield and yield components) parameters measured were not significantly (p < 0.05) influenced by drought stress. There were significant (p < 0.05) interactions between water stress and variety. The three sorghum varieties responded differently (p < 0.05) in terms of FSAW dynamics at both the vegetative and reproductive stages. SAMSORG 44 had a comparatively superior performance, as indicated by its relatively high moisture stress tolerance. These varieties are suggested to be suitable for cultivation under severe drought conditions.
AI-Augmented IS-IS Routing Framework for Optimized IoT Networks
Authors: Mahendran A. , Chilambarasan N. R.
Published: December 2024

In the rapidly evolving landscape of the Internet of Things (IoT), efficient and reliable routing is crucial for maintaining optimal network performance. Traditional IS-IS routing protocols, while foundational, often fall short in dynamic IoT environments due to their static nature. This paper presents an AI-augmented IS-IS routing framework, leveraging the capabilities of reinforcement learning, specifically Q-learning, to dynamically adjust routing paths. The proposed framework aims to enhance energy efficiency, reduce latency, and improve packet delivery ratios. Through comprehensive simulations, our approach demonstrates substantial improvements over conventional routing protocols. Additionally, this study addresses the challenges associated with implementing AI-driven routing in IoT networks and explores potential future enhancements to further optimize performance.
Wahnbildungen
Authors: Moscati Antonella
Published: December 2024

Ein übersetzter Auszug aus dem autotheoretischen Essay "Deliri", der die Erfahrung einer psychotischen Phase beschreibt.
Lieber mit Riss als gar nicht
Authors: Kläui Christian
Published: December 2024

Der Beitrag erwägt die These der postödipalen Gesellschaft und argumentiert für ihre zeitdiagnostische Triftigkeit, aber plädiert, noch mit Lacan, für lieber eine Dekonstruktion des Ödipuskomplexes, nützlicher sein könnte, um das Modell von Menschen die die neoliberale Therapiemodelle unterstützen, kritisieren.
Welche Gewähr?
Authors: Rath Claus-Dieter
Published: December 2024

Der Beitrag kreist um die Figur des Gewährsmanns bzw. der Gewehrperson, die in den Exposé von RISS 100 sowie in Freuds Text auch auftaucht. Gewährpersonen sind jeweils Psychoanalytiker, um Analyse stattfinden zu lassen, sowie Analysantinnen, um Analyse weiter stattfinden zu lassen. Der Austausch unter Kolleginnen sowie die Transmission sind unverzichtbare Elemente des Analysieren können, und somit genauso Gewährpersonen. Wenn die Psychoanalyse immer wieder erneut erfunden werden muss, ist es die Kulturarbeit die sie ermöglicht von keine "absolvierte" Ausbildung garantiert.
Zukunft ohne Gewähr?
Authors: Frühauf Marie
Published: December 2024

Kritische Auseinandersetzung mit pädagogischen Machbarkeitsphantasien im Angesicht der Klimakrise.
REAL OR REEL: A COMPARATIVE ANALYSIS OF AUTHENTIC AND PHISHING EMAILS
Authors:   Assistant Professor, Language and Letters Department, Bukidnon State University, Malaybalay City,8700 Bukidnon, Philippines., C. Cardona Julysa
Published: December 2024

Although technology can be used for good reasons, the same can be exploited by cybercriminals for malicious intents and activities like phishing attacks. The use of phishing emails in such crimes makes it riveting to understand languages role in such a deceptive undertaking. Hence, this qualitative work comparatively analyzed the language correctnessand deviations, illocutionary speech acts, and persuasion principles of phishing and authentic emails to draw the line that separates the genuine from the copycat. The results reveal that although phishing emails commit more types of language deviations relating to parallelism, pluralization, preposition usage, subject-verb agreement, sentence fragments, and possessive form, there are also instances of faulty use of punctuation markers in authentic emails, thereby making it unreliable to judge an emails veracity through language correctness or deviations alone. Moreover, the simultaneous use of expressive, directive, and representative acts was found in phishing and authentic emails,while the former has added the commissive act through subtle threats. Also, authority was typical in both phishing and authentic emails, while the former employs other persuasion principles such as reciprocity, social proof, and liking, indicating that phishers not only impersonate legitimate institutions but also stimulate the victims emotions. Finally, this study draws that what sets a real email apart from the reeling one is not mainly the correctness or the deviations in an emails language, but rather, it is the phishing emails tendency to evoke feelings of fear and a sense of urgency behind the text that may give their dishonesty away.
Unveiling the link of country compliance, risks, and cost of capital in socially responsible investing
Authors: Ekawati Erni , Frilichia Alik Napoh Charla , Fildania Dhiru Theodora , Wijaya Kusuma Indra
Published: December 2024

The study provides empirical evidence on the cost implications of socially responsible investing (SRI) in relation to Environmental, Social, and Governance (ESG) preferences. Specifically, it examines whether socially responsible investors incur higher costs to meet non-pecuniary goals and how government involvement can offer rewards to socially responsible investors in supporting the realization of the United Nations’ Sustainable Development Goals (SDGs). Using panel data regression, this study analyzes ESG scores and financial and return data of 1,450 firm-year observations in ASEAN-5 countries over the period 2015–2022. The findings reveal that firms implementing ESG practices experience an increase in their cost of capital (CoC), supporting the notion that ESG investment requires a sacrificial cost. Even firms with low operational risks face rising CoC when implementing ESG principles. However, the study also finds that firms located in countries with better government effectiveness and stronger control of corruption benefit from a reduction in CoC, despite ESG implementation. Conversely, country risks, particularly those related to environmental pollution, exacerbate the CoC for firms adhering to ESG criteria. Overall, the results suggest that while country-level governance can reward socially responsible investors by mitigating CoC, country risks such as pollution pose additional burdens, highlighting the need for government intervention to incentivize SRI and align it with global sustainability goals.
AcknowledgmentThis research was funded by the Indonesian Ministry of Education, Research, and Technology (DRTPM), Fundamental Research Grant in 2024 [0609.10/LL5-INT/AL.04/2024,359/D.01/LPPM/2024].
Huertos comunitarios sostenibles: una guía para su implementación
Authors: Miranda Villa Patricia Paola , Rodríguez Fonseca Francis Yuliana , Camargo Caicedo Yiniva
Published: December 2024

La cartilla Huertos comunitarios sostenibles: guía para su implementación es un recurso informativo, resultado del proyecto de investigación realizado en la comunidad de la finca Providencia, en Fundación, Magdalena. Ofrece una guía básica para implementar huertos comunitarios utilizando métodos ecológicos que promueven la conservación de la biodiversidad local. Además de destacar los beneficios ambientales, resalta la importancia de fortalecer los lazos comunitarios, promoviendo el bienestar individual y colectivo mediante el intercambio de conocimientos, el suministro continuo de alimentos frescos y de alta calidad, y el potencial de generar ingresos con la venta de los productos cultivados. La cartilla brinda herramientas para la toma de decisiones informadas según el espacio de terreno disponible y abarca aspectos fundamentales para el diseño y mantenimiento de un huerto, desde la preparación del terreno hasta el cuidado de las plantas, incluyendo actividades esenciales para lograr el cultivo exitoso de hortalizas. También ofrece consejos prácticos para mantener la salud de las plantas, recetas naturales para el control de plagas con recursos accesibles, y recomendaciones sobre el uso de residuos orgánicos para la elaboración de compost, contribuyendo así a un manejo más sostenible y autosuficiente de los recursos del entorno.
Resiliência docente
Authors: Silva Roberta Souza da , Santos David Moises Barreto
Published: December 2024

A resiliência docente tem recebido cada vez mais atenção devido aos desafios crescentes enfrentados pelos professores, porém é um tema pouco explorado no Brasil. Este artigo apresenta uma revisão narrativa da literatura sobre resiliência docente com base em estudos teóricos e empíricos relevantes. A revisão identificou e discutiu categorias-chave: características da resiliência docente, desafios laborais, fontes de suporte, modelos de resiliência docente, implicações da resiliência para o desenvolvimento profissional e a relação com outros constructos como bem-estar e projeto de vida. Os achados mostram que resiliência docente é um fenômeno complexo e multidimensional, influenciado por desafios pessoais e contextuais, e descrevem como os professores conseguem sustentar sua capacidade de adaptação positiva diante das adversidades. Elas destacam que a resiliência não é inata, mas pode ser desenvolvida e fortalecida através de suporte adequado, como ambientes colaborativos e políticas públicas. Outros achados e implicações são discutidos.
Interpretar como? Em busca da informação (geo)turística no site do Parque Nacional do Itatiaia
Authors: Uliano Rocha Diego , Eustáquio Fonseca Filho Ricardo
Published: December 2024

A geodiversidade é frequentemente ameaçada pela perda ou degradação resultantes das atividades humanas. Por meio do geoturismo, pode-se contribuir para a proteção e conservação desse patrimônio natural. Assim, o objetivo da pesquisa foi identificar informação qualificada dos atrativos do Parque Nacional de Itatiaia. Os métodos consideraram a pesquisa documental e a análise de conteúdo. A partir dos resultados obtidos, conclui-se que a unidade de conservação não oferece, neste sítio eletrônico, informações relevantes sobre a geodiversidade existente em sua circunscrição.
Fórum comunitário participativo: um estudo de caso no município de icapuí/ce
Authors:   , Silva Daniel Freitas
Published: December 2024

O fomento à participação social é uma das premissas da Constituição Federal (1988) e os fóruns participativos são uma importante ferramenta que viabiliza o controle social. Nesse sentido, o presente trabalho apresenta estudo de caso sobre o Fórum Comunitário Participativo – FCP implantado no município de Icapuí-CE, com o intuito de verificar até que ponto o FCP promove de fato a democratização e possibilita a participação da população de Icapuí/CE na tomada de decisão da administração pública municipal. Adota-se como procedimento de coleta de dados o estudo de caso, classificado quanto ao objetivo como exploratório e quanto à abordagem como qualitativa, sendo utilizado como técnicas a revisão bibliográfica, a observação participante e a aplicação de questionários. Pretendeu-se com este trabalho verificar a implantação do FCP e seu processo de institucionalização com o intuito de buscar quais ações são necessárias para potencializa-lo como uma política de estado. Foi constatado que o FCP é tido como uma experiência positiva para seus participantes, mas que necessita ser aprimorado, principalmente quanto a sua metodologia de acompanhamento de demandas, prestação de contas, tempo de deliberações e periodicidade. Nesse sentido, propõe-se a produção de regimento interno que regulamente a funcionalidade do Fórum, fundamentado na metodologia da “reunião em espaço aberto” e a sua normatização legal mediante projeto de lei, tornando-o em política pública de estado que vincule o atual e próximos gestores.