bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis between Adrenal MRI Mass Size and 1 mg Dexamethasone Suppression Test in Patients with Adrenal Incidentaloma
Authors: Karakaya Pinar , Yaprak Bulent , Ozdemir Bahar , Kocoglu Hakan
Published: August 2023

This study aimed to investigate the correlation of adrenal magnetic resonance imaging (MRI) mass size and 1 mg dexamethasone suppression test results in patients with adrenal incidentaloma diagnosis. Eighty-six patients (82.6% female) with incidentally discovered adrenal masses, diagnosed and treated in the Department of Endocrinology Bakirkoy Dr. Sadi Konuk Education and Research Hospital between June and August 2017, were included in the analysis. All the patients evaluated for their hormonal functionality. 24-h urinary excretion of cortisol did not correlate with tumor size. But there was a positive correlation between longer adrenal nodule diameter and metanephrine, and there was a negative correlation between shorter adrenal nodule diameter and renin levels. We found that smaller and clinically “silent” tumors often do not demonstrate subclinical hormonal activity.
Quality of Genom in Type II Diabetes Mellitus Patients in Viewed of Temperature, Storage Duration, Number of Leukocyte
Authors: Puspitasari Puspitasari , Rinata Evi , Dijaya Rohman , Aprilia Siska , Trikumalasari Dina , Nur Azzah Livia , Fanani Qilmia , Mushlih Miftahul , Aliviameita Andika , Delta Dian
Published: August 2023

Type II Diabetes Mellitus is a disorder caused by genetic and environmental factors. Molecular analysis of T2DM abnormalities has been carried out. But the analysis in sample preparation especially the stages of DNA isolation has not been done much. The aims of this study are to investigate the effect of temperature, storage duration and level of white blood cell (WBC) with Genome Quality in T2DM. The treatment (n:10) which were divided into several tubes and then stored at 4 °Ϲ, 25 °Ϲ and 32 °Ϲ for 21 days. To determining storage duration effect, we use periodically isolation of DNA (3, 15 and 30 days) after sampling. The effect of WBC with DNA quality was carried out using 17 samples. DNA isolation was done by the DNA Isolation Kit manual without modification and then tested qualitatively and quantitatively. Based on this research, it can be concluded there is a correlation between the numbers of WBC with DNA quality. The higher the number of WBC, the higher DNA concentration (r: 0.818. p value: 0.000). The concentration of DNA at a temperature of 4°Ϲ (135.1 ± 165.2 ng / µl) was higher compared with the temperature treatment 25 ° Ϲ (29.7 ± 36.5 ng / µl) and 32 ° Ϲ (22.14 ± 7.13 ng / µl) (p
Detection of Salmonella typhi Using Multiplex and Monoplex PCR in Tifoid Fever Patients
Authors: Aliviameita Andika , Agustin Meryn Linanda , Puspita Anggie Wedha , Mushlih Miftahul , Puspitasari Puspitasari , Purwanti Yanik , Wisaksono Arief
Published: August 2023

Typhoid fever is a disease caused by Salmonella typhi infection. This disease is still a global problem. The purpose of this study was to develop a rapid detection method for Salmonella using molecular methods utilizing Inv A and Fim-C Genes. Two methods compared, which are Multiplex and monoplex PCR. The sample is in the form of the patient's blood, which is stored at 3 ml EDTA vacutainer tube consisting of 10 positive samples and five negative samples. The criteria for samples used previously have tested by widal/ immunoserology (titer more than 1/160). The results showed that multiplex PCR for detection of Salmonella using the Inv A gene and fim c gene not recommended because too many bands produced. The application of monoplex in the Inv A gene gives better results than the Fim C gene. In conclusion, the monoplex application on Inv A gene recommended than Fim C gene used to detect S. typhi in human blood samples.
Renal Function Evaluation in Secondary Amyloidosis According to Location of Deposition
Authors: Özçelik Serhat , Şahin Gülizar Manga
Published: August 2023

It aimed to evaluate the renal functions according to the accumulation site of amyloid in patients diagnosed with secondary amyloidosis by renal biopsy. Fifty patients diagnosed with secondary amyloidosis, who referred to the nephrotic syndrome outpatient clinic included in the study. According to the findings of renal biopsy, only-glomerular amyloid deposition (group- 1) detected in 9 patients and glomerular+ tubulointerstitial deposition (group- 2) identified in 41 patients. Serum creatinine, creatinine clearance, and total proteinuria levels compared between groups at the time of presentation and on 3rd, 6th, 12th, and 24th months. Initial and subsequent serum creatinine, creatinine clearance, and total proteinuria levels not found to be significantly different between groups (p>0,05 for all). Among subjects with only-glomerular deposition, statistically significant descents in total proteinuria, when compared to initial levels, were observed from the beginning of the 6th month to the end of the 24th month (p
Retrospective investigation of acute kidney injury in postoperative patients in ICU
Authors: TAŞDEMİR MECİT Bilge Banu
Published: August 2023

Aims: The development of acute kidney injury (AKI) in the postoperative period is associated with increased morbidity and mortality. This study aims to determine the incidence of postoperative acute kidney injury (AKI) and the factors affecting the development of AKI in the intensive care unit (ICU) and to evaluate the outcomes of the patients.

Methods: Postoperative patients hospitalized in the ICU between December 2021 and January 2023 were retrospectively analyzed, and 192 patients were included in the study. Kidney disease: patients with and without AKI were identified using the improving global outcomes (KDIGO) criteria.

Results: While 150 of the patients did not develop AKI (non-AKI group), 42 of them developed acute kidney injury (AKI group). The patients were operated on mostly by the orthopedics clinic (58.9%) and operated on at least by the urology clinic (2.1%) were taken to the intensive care unit. 39.6% of the patients underwent emergency surgery, and 60.4% underwent elective surgery. 57.1% of the AKI group and 34.7% of the non-AKI group had emergency surgery (p=0.008).

Conclusion: In our study, age, timing of surgery, use of diuretics, and use of vasopressors were found to be associated with the development of postoperative AKI. In addition, comorbid diseases such as diabetes mellitus, hypertension, coronary artery disease, and cerebrovascular disease have also been found to be associated with AKI. Mortality, length of stay in the intensive care unit, and need for mechanical ventilation (MV) were also higher in our postoperative intensive care patients who developed AKI than in patients who did not develop AKI.
Chapter 4. Semantic Web Machine Learning Systems: An Analysis of System Patterns
Authors: Waltersdorfer Laura , Breit Anna , Ekaputra Fajar J. , Sabou Marta , Ekelhart Andreas , Iana Andreea , Paulheim Heiko , Portisch Jan , Revenko Artem , ten Teije Annette , van Harmelen Frank
Published: August 2023

In line with the general trend in artificial intelligence research to create intelligent systems that combine learning and symbolic techniques (a.k.a. neuro-symbolic systems), a new sub-area has emerged that focuses on combining machine learning (ML) components with techniques developed by the Semantic Web (SW) community – Semantic Web Machine Learning (SWeML for short). Due to the rapid growth of this area and its impact on several communities in the last two decades, there is a need to better understand the space of these SWeML Systems, their characteristics, and trends. Of particular interest are the emerging variations of processing patterns used in these systems in terms of their inputs/outputs and the order of the processing units. While several such neuro-symbolic system patterns were identified previously from a large number of papers, there is currently no insight into their adoption in the field, e.g., about the completeness of the introduced system patterns, or about their usage frequency. To fill that gap, we performed a systematic study and analyzed nearly 500 papers published in the last decade in this area, where we focused on evaluating the type and frequency of such system patterns. Overall we discovered 41 different system patterns, which we categorized into six pattern types. In this chapter we detail these pattern types, exemplify their use in concrete papers and discuss their characteristics in terms of their semantic and machine learning modules.
Chapter 19. Neuro-Symbolic Spatio-Temporal Reasoning
Authors: Lee Jae Hee , Sioutis Michael , Ahrens Kyra , Alirezaie Marjan , Kerzel Matthias , Wermter Stefan
Published: August 2023

Knowledge about space and time is necessary to solve problems in the physical world. Spatio-temporal knowledge, however, is required beyond interacting with the physical world, and is also often transferred to the abstract world of concepts through analogies and metaphors. As spatial and temporal reasoning is ubiquitous, different attempts have been made to integrate this into AI systems. In the area of knowledge representation, spatial and temporal reasoning has been largely limited to modeling objects and relations and developing reasoning methods to verify statements about objects and relations. On the other hand, neural network researchers have tried to teach models to learn spatial relations from data with limited reasoning capabilities. Bridging the gap between these two approaches in a mutually beneficial way could allow us to tackle many complex real-world problems. In this chapter, we view this integration problem from the perspective of Neuro-Symbolic AI. Specifically, we propose a synergy between logical reasoning and machine learning that will be grounded on spatial and temporal knowledge. A (symbolic) spatio-temporal knowledge base and a base of possibly grounded examples could provide a dependable causal seed upon which machine learning models could generalize. Describing some successful applications, remaining challenges, and evaluation datasets pertaining to this direction is the main topic of this contribution.
Chapter 22. Semantic Loss Functions for Neuro-Symbolic Structured Prediction
Authors: Ahmed Kareem , Teso Stefano , Morettin Paolo , Di Liello Luca , Ardino Pierfrancesco , Gobbi Jacopo , Liang Yitao , Wang Eric , Chang Kai-Wei , Passerini Andrea , Van den Broeck Guy
Published: August 2023

Structured output prediction problems are ubiquitous in machine learning. The prominent approach leverages neural networks as powerful feature extractors, otherwise assuming the independence of the outputs. These outputs, however, jointly encode an object, e.g. a path in a graph, and are therefore related through the structure underlying the output space. We discuss the semantic loss, which injects knowledge about such structure, defined symbolically, into training by minimizing the network’s violation of such dependencies, steering the network towards predicting distributions satisfying the underlying structure. At the same time, it is agnostic to the arrangement of the symbols, and depends only on the semantics expressed thereby, while also enabling efficient end-to-end training and inference. We also discuss key improvements and applications of the semantic loss. One limitations of the semantic loss is that it does not exploit the association of every data point with certain features certifying its membership in a target class. We should therefore prefer minimum-entropy distributions over valid structures, which we obtain by additionally minimizing the neuro-symbolic entropy. We empirically demonstrate the benefits of this more refined formulation. Moreover, the semantic loss is designed to be modular and can be combined with both discriminative and generative neural models. We illustrate this point by integrating the semantic loss into generative adversarial networks, yielding constrained adversarial networks, a novel class of deep generative models able to efficiently synthesize complex objects obeying the structure of the underlying domain.
Contributions of Cardiovascular Burden, Peripheral Inflammation, and Brain Integrity on Digital Clock Drawing Performance in Non-Demented Older Adults
Authors: Dion Catherine , Tanner Jared J. , Libon David J. , Price Catherine C.
Published: August 2023

Background: Greater cardiovascular burden and peripheral inflammation are associated with dysexecutive neuropsychological profiles and a higher likelihood of conversion to vascular dementia. The digital clock drawing test (dCDT) is useful in identifying neuropsychological dysfunction related to vascular etiology. However, the specific cognitive implications of the combination of cardiovascular risk, peripheral inflammation, and brain integrity remain unknown. Objective: We aimed to examine the role of cardiovascular burden, inflammation, and MRI-defined brain integrity on dCDT latency and graphomotor metrics in older adults. Methods: 184 non-demented older adults (age 69±6, 16±3 education years, 46% female, 94% white) completed dCDT, vascular assessment, blood draw, and brain MRI. dCDT variables of interest: total completion time (TCT), pre-first hand latency, digit misplacement, hour hand distance from center, and clock face area. Cardiovascular burden was calculated using the Framingham Stroke Risk Profile (FSRP-10). Peripheral inflammation markers included interleukin (IL)-6, IL-8, IL-10, tumor necrosis factor-alpha, and high sensitivity C-reactive protein. Brain integrity included bilateral entorhinal cortex volume, lateral ventricular volume, and whole brain leukoaraiosis. Results: FSRP-10, peripheral inflammation, and brain integrity explained an additional 14.6% of the variance in command TCT, where FSRP-10 was the main predictor. FSRP-10, inflammatory markers, and brain integrity explained an additional 17.0% in command digit misplacement variance, with findings largely driven by FSRP-10. Conclusion: Subtle graphomotor behavior operationalized using dCDT metrics (i.e., TCT and digit misplacement) is partly explained by cardiovascular burden, peripheral inflammation, and brain integrity and may indicate vulnerability to a disease process.
Mediation Effect of Brain Volume on the Relationship Between Peripheral Inflammation and Cognitive Decline
Authors: Zhuo Bingting , Zheng Dashan , Cai Miao , Wang Chongjian , Zhang Shiyu , Zhang Zilong , Tian Fei , Wang Xiaojie , Lin Hualiang
Published: August 2023

Background: Studies have reported the associations between inflammation, brain volume, and cognition separately. It is reasonable to assume peripheral inflammation may contribute to cognitive decline through brain volume atrophy. Objective: To examine the associations between peripheral inflammation, brain volume, and cognition among adults, and to investigate whether brain volume atrophy mediates the inflammation-cognition relationship Methods: We retrieved 20,381 participants with available data on peripheral inflammation, brain volume, and cognition from the UK Biobank cohort. Cognitive function was assessed by performance on cognitive tasks probing various cognitive domains. Brain volumes were measured by magnetic resonance imaging (MRI). Multivariable linear models were used to investigate the associations between three peripheral inflammatory indexes (C-reactive protein, systemic immune-inflammatory index, neutrophil-to-lymphocyte ratio), brain volume, and cognition. Mediation analyses were conducted to assess the potential mediating effect of brain volume atrophy. All results were corrected for multiple comparisons using the false-discovery rate (FDR). Results: Peripheral inflammation was inversely associated with grey matter volume (GMV), white matter volume (WMV), and cognition after adjusting for potential covariates. For instance, CRP was associated with the GMV of left parahippocampal gyrus (β= –0.05, 95% confidence interval [CI]: –0.06 to –0.04, pFDR =1.07×10-16) and general cognitive factor (β= –0.03, 95% CI: –0. –0.04 to –0.01, pFDR = 0.001). Brain volume atrophy mediated the inflammation-cognitive decline relationship, accounting for 15–29% of the overall impact. Conclusion: In this cohort study, peripheral inflammation was associated with brain volume atrophy and cognitive decline. Brain atrophy may mediate the inflammation-cognitive decline relationship.
Multi-objective hybrid optimization for micro strip patch antenna design
Authors: Bommu Samuyelu , R Rajalakshmi , Chincholkar Yugendra D. , Mohite Utkarsha L.
Published: August 2023

Due to their low price, light weights, as well as simple installation, Micro strip Patch Antennas (MPAs) have been made to perform in a double and multi-band applications. The MP receiver is created with an Electromagnetic Band Gap (EBG) structure in order to decrease the micro strip patch cross-polarized radiation but also achieve the crucial radiation criteria. The polymeric liquid crystals substratum is employed to decrease raw material costs, and also the applicable shape framework are employed to enhance receiver execution. We have established a new optimization based method which has two operating stages. In the begining stage, we have designed a Micro strip patch antenna with certain parameters. Afterwards, these design parameters length, width, height, substrate thickness under area such as get optimized by the newly introduced Battle Royale Customized Spider Monkey Optimization (BRCSMO) algorithm in order to get an antenna with higher performance. We have evaluated the proposed method with regard to measures like receiver profit, productivity, bandwidth, decline loss as well as Total Active Reflection coefficient (TARC) and the outcomes showed that this proposed technique can offer superior outcomes than other approaches.
Conditions for simulation of transonic flutter of aerodynamic control surfaces of supersonic aircraft in wind tunnels
Authors: Safronov Oleksandr , Semon Bohdan , Nedilko Oleksandr , Horina Anna
Published: August 2023

The transonic flutter of the aerodynamic control surfaces of supersonic and hypersonic aircraft refers to those phenomena of dynamic aeroelasticity, the assessment of whichin a flight experiment is dangerous. Since there is still no universally accepted mathematical model of the occurrence of this phenomenon, tests of dynamic-like models in wind tunnels can be classified as basic and safe methods for evaluating the characteristics of transonic flutter. Therefore, the substantiation of the conditions for modeling transonic flutter, which allow the transfer of the results of blowing of dynamic-like models in wind tunnels to full-scale aircraft designs, remains an actual scientific problem.The article proposes one of the possible approaches to justifying the conditions for modeling transonic flutter of aerodynamic control surfaces in wind tunnels, which is based on the analysis of a nonlinear mathematical model of the occurrence of this phenomenon.Based on the analysis of this mathematical model, it was determined that, in addition to the conditions for modeling transonic flutter in wind tunnels, which are due to the geometric similarity of the system "carrying aerodynamic surface – aerodynamic control surface", additional conditions for modeling this phenomenon should be the following dimensionless quantities of nature and model:- amplitudes of oscillations of nature and model;- numbers M at which transonic flutter occurs;- logarithmic decrements of oscillations of aerodynamic control surfaces;- Strouhal numbers;- ratio of gas density to material density of aerodynamic control surfaces;- the adiabatic index k=1.405, that is, the working body in the wind tunnel should be air.Blowing of dynamically similar models must be carried out in wind tunnels of a continuous type, subject to conditions  (s-1).
Nutritional Quality and Yield Performance of Plum (Prunus domestica) Varieties Grown in Punjab, Pakistan
Authors: Ahmad Noman , Ahmad Sarfraz , Tariq Iqra , Ali Iftikhar , Usman Muhammad , Tariq Humna , Murtaza Ghulam , Ahmad Abrar
Published: August 2023

Pakistan is ranked 17th in the world for plum production, with a total output of 67,000 tonnes. In terms of area and production, plum (Prunus domestica) is Pakistan's second largest stone fruit, after peach. Plum (Prunus domestica L.) is a temperate zone fruit crop, made up of different varieties. This study was carried out to evaluate the nutritional quality and yield performance of five different plum varieties (Methley, Shakar Prune, Santa Rosa, Hersminar, and Red Beaut) grown in the Punjab province of Pakistan. Plum samples were collected from the Horticultural Research Station, Nowshera (Soon Valley), Pakistan during May 2021 and analyzed for fruit yield and nutritional quality parameters. The maximum fruit fresh weight (52.9g) was recorded in Red Beaut and the lowest fresh weight (12.4 g) in Methley. The cultivar with the highest nutritional value was Shakar Prune with 16.4% of total soluble solids (TSS) and 12.2% of total sugars content, whereas the lowest nutritional value was recorded in Herisminar with total soluble solids (TSS) and total sugars content of 14.8% and 10.0%, respectively. All varieties showed significant variation in terms of fresh weight, total soluble solids (TSS), and total sugars. The results showed the yield performance and nutritional quality of different plum varieties, with Red Beaut and Shakarprune cultivars highlighted as the best. The study concluded that yield performance and nutritional quality depend strongly on the respective plum variety.
Factors Influencing the Laptop Buying Behavior of Students in Vietnam
Authors: Ngo Van Quang
Published: August 2023

This study examines the various factors related to sales and laptop features that directly impact the buying behavior of students in Hanoi. Specifically, it demonstrates how specifications, enhanced features, price and payment conditions, design, and brand directly influence students' laptop buying decisions. This was done through the design and distribution of questionnaires. The study obtained 214 responses that were encrypted and cleaned using SPSS software, followed by reliability testing, exploratory factor analysis, correlation, and multivariate regression analysis.
Evaluation the Sensitivity and Specificity of Fucose and Some Biochemical Parameters as an Indicator of Therapeutic Response to Metformin in Polycystic Ovary Syndrome
Authors: Mahmood Nasreen  Shakir , Alsamarai Rafah , Alsamarai Rawaa
Published: August 2023

The present study aimed to evaluate the sensitivity and specificity of fucose and some biochemical parameters, as an indicator of therapeutic response to Metformin in patients with recently diagnosed with Polycystic Ovary Syndrome-PCOS undergoing treatment. This study was conducted from 1/9/2022 to 1/11/2022. In 90 blood samples were collected from women aged between (35-18) years old. Of these, 30 samples were taken from women who had recently been diagnosed with polycystic ovary syndrome as a first group-G1, and another 30 samples were taken from the same group of women after taking metformin medication as second group-G2, compared to 30 samples taken from healthy women with no history of the disease (as a control group-C). Samples were collected from women's clinics and external laboratories (after diagnosis from the doctor) in Samarra city/ Salah Ul-Din. The study includes determination of the concentration of sex hormones(Follicle stimulating hormone-FSH, luteinizing hormone-LH, and testosterone) and some biochemical parameters(Galactose, blood glucose, total fucose-TF, and fucose binding protein-FBP) in sera of samples under investigation. There was a significant increase in the levels of FSH and Glucose in a G1 at a probability level (P≤0.05). However, there was a significant decrease in total fucose and FBP, with no-significant difference in the levels of LH, testosterone, Galactose as  compared with the control group. There was a significant increase in G2 at a probability level (P≤0.05) in the levels of Testosterone,  Galactose, glucose with a significant decrease in the levels of TF and FBP, with no-significant difference in the level of LH, FSH and transaminases enzymes as  compared with the control group. The study also include study the Receiver operating characteristic-ROC , In G1 as compared with C showed that the Sensitivity was also recorded as highest for galactose , In G2 as compared with C showed that the area under curve was outstanding for galactose, Sensitivity was also recorded as highest for galactose , In G1 as compared with  G2 showed that the area under curve was outstanding for  galactose. Sensitivity was also recorded as highest for galactose, then for Testosterone and total fucose. From the above results we can conclude that the level of fucose may be used as a diagnostic biomarker for polycystic ovary syndrome and also for treatment response with metformin. We conclude from the current study that the level of fucose may be considered a diagnostic indicator for polycystic ovarian cysts, as well as an indicator of the therapeutic response to uremia in patients.
ANALISIS KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMP PADA MATERI LIMAS DITINJAU DARI PERBEDAAN GENDER
Authors: Wahyudi Rizky , Hafriani  , Darwani
Published: August 2023

Mathematical problem-solving ability became one of the abilities that students must possess. However, based on the results of previous research, it was stated that there were differences between the abilities of male and female students in problem-solving abilities, so it required an in-depth understanding of mathematical problem-solving abilities based on gender. This study aims to determine the mathematical problem-solving abilities of junior high school students on pyramid material regarding gender differences. This research is qualitative research with a descriptive research type. The subjects in this study consisted of 6 students, consisting of 3 male and three female students, with high, medium and low students. Data were collected through written tests and interviews, then analyzed descriptively, including data reduction, data presentation and drawing conclusions. The results of the study were (1) female and male subjects in the high category fulfilled all indicators of problem-solving ability, but male subjects were less thorough than female subjects (2) female and male subjects in the medium category fulfilled three indicators of problem-solving ability problems, and made mistakes in making mathematical calculations, but male subjects made more mistakes than female subjects (3) Male and female subjects in the low category only met one indicator of problem-solving ability.
Experimental methods in sociology used in sensitive questions: List experiment example
Authors:   Astana IT University, Zhanadilova A.
Published: August 2023

This article explores experimental methods in sociology that are used to address sensitive questions. Sensitive questions are those that involve socially stigmatized or taboo subjects, such as illegal activities, personal beliefs, and sexual behavior. The use of traditional survey methods to investigate sensitive questions may lead to response bias or social desirability bias. To overcome these limitations, scientists have developed innovative experimental methods, such as the list experiment. The list experiment is a survey-based technique that provides respondents with a list of items and asks them how many items on the list they have experienced or endorse. Unlike direct questioning, this method allows respondents to express their opinions anonymously and reduces social desirability bias. Moreover, the list experiment can estimate the prevalence of sensitive behaviors or attitudes without revealing individual responses, which makes it particularly useful in studying politically or socially sensitive topics. This article describes the theoretical foundations, design, and implementation of the list experiment. With the help of the VOSviewer program, a bibliographic analysis was carried out based on Scopus database. At the same time, it discusses the advantages and limitations of this method compared to other experimental techniques and highlights some of its practical applications in sociological research. Overall, this article provides a comprehensive overview of the list experiment and its contribution to the advancement of sociological research.
Improving the well-being of the population in Central Asia: a comparative analysis
Authors:   L.N. Gumilyov Eurasian National University, Smagambet B.Zh. , Aikynbaikyzy A. ,   L.N. Gumilyov Eurasian National University
Published: August 2023

The article deals with the topical issue of assessing the level of well-being of the population in the countries of Central Asia. Theoretical, methodological and applied aspects of measuring the level of well-being of the population are discussed. The evolution of the theory of the formation of the state of mass welfare is proposed within the framework of three conceptual methods: socio-market, socially balanced and socially liberal. Objective, subjective and mixed methodologies are described, data based on macroeconomic indicators (the World Bank, the International Labor Organization, the World Health Organization, the Interstate Statistical Committee of the CIS countries) and indicators based on a person’s assessment of their financial situation, social capital (the Study of World Values, the Eurasian Barometer) are analyzed, an overview of the discussion within the category is given happiness. Thus, the conceptual foundation of socio-economic policy in the countries under consideration is being studied. The article analyzes the main models for evaluating the effectiveness of government agencies; on the basis of statistical data, a comparative analysis of the main factors of the level and quality of life of Central Asian countries is carried out. In order to describe the well-being of the population in Kazakhstan, Kyrgyzstan, Uzbekistan, Tajikistan and Turkmenistan, criteria and indicators such as gross domestic product per capita, poverty level, unemployment rate, average monthly nominal wages of the population, the structure of household monetary expenditures, the level of education and health, the level of social protection, an individual’s assessment of their own well-being are defined. The results of the study show differences in macroeconomic indicators and the subjective assessment of the population of their socio-economic situation. The incompleteness and unavailability of data in the course of analytical work made a detailed comparative analysis difficult.
EFEKTIVITAS FORMULASI PUPUK ORGANIK DAN ANORGANIK TERHADAP PRODUKSI STRAWBERRY (Fragaria x ananassa) DAN KARAKTERISTIK FISIKA KIMIA TANAH PERTANIAN
Authors: Ariz Ahmad , Andika Rama , Annita  , Rahmedi Fachrenjani , Azizah Wirda , Novika  , Aflizar
Published: August 2023

Penggunaan pupuk anorganik (Urea, SP36, Dolomit) tanpa manajemen yang baik dan tanpa diimbangi dengan penggunaan pupuk organik (Pukan) dapat menyebabkan degradasi tanah yang berujung penurunan produktivitas tanaman. Tujuan penelitian ini untuk mengetahui formula dosis pupuk terbaik pada pertanaman strawberry, dan untuk mencari dampak yang diakibatkan formula dosis pupuk (Formula POA 1, Formula POA 2, Formula POA 3, Formula POA 4) terhadap perubahan sifat fisika dan kimia tanah. Penelitian dilakukan pada bulan September – Desember 2022 di lahan Politeknik Pertanian Negeri Payakumbuh. Metode yang dipakai dalam pengambilan sampel tanah adalah purposive sampling. Penelitian juga menggunakan Analisa Multiple Regression, Korelasi, Estimasi penggunaan pupuk dan Rumus-rumus sifat fisika tanah. Pupuk yang digunakan berupa pupuk anorganik yaitunya Urea, SP36, Dolomit dan pupuk organik yaitu pupuk kandang. Parameter yang di ukur adalah data pertumbuhan dan produksi tanaman. Hasil penelitian membuktikan adanya pengaruh formula yang diberikan oleh pupuk anorganik dan organik terhadap hasil produksi dan sifat fisika kimia tanah. Percobaan terbaik menghasilkan 225g buah strawberry dengan penggunaan Formula POA 2 yang dilakukan pada plot 1m x 1m dengan pengaruh sifat fisika kimia tanah yang terlihat yaitu % Qvr, % Qms, TDS, % Qm, % Ø (porositas) serta pengaruh pupuk anorganik dan organik
Didactic Regularities, Principles and Methods of Preparing Prospective Primary School Teachers to Pedagogical Activity
Authors: Martynova R. , Bodnar S.
Published: August 2023

Nowadays modern primary schools should significantly improve both the content of education for younger students and the forms of teaching. It occurs due to the social demand of society to train the students ready to participate in the life of their country, which is rapidly developing in the fields of science, technology and culture. Such requirements regarding the improvement of primary education standards are reflected in the Concept of implementation of the state policy of general secondary education reform “New Ukrainian School” for the period up to 2029. This work is an attempt to present one of the possible options for solving the modern problems of primary school development. Purpose. To determine the theoretical and practical content of training prospective primary school teachers for their professional activity. Methods. Study and analysis of psychological and pedagogical literature on thetopic of the research, generalization of work experience of scholars-philologists, pedagogues and specialists in various subject areas. Results. The authors have analyzed and specified psychological and pedagogical components of prospective primary school teachers’ professional competency. One of thepedagogical competency components, namely, didactic competency has been revealed in detail. Thus, the didactic regularities of organizing the primary school students’ teaching process have been grounded Conclusion. The principles of organizing the teaching process of primary school pupils are the following: computer presentation and activation of the material under study; gaming interaction of students in the process of exchanging information received at the lessons; solving tasks of the practical knowledge application in the everyday environment. The methods of implementation of these principles are functional-based and activity-based, gaming, verbal, visual, and multimedia.
Tratamento Cirúrgico Conservador do Câncer de Mama
Authors: Luini Alberto , Farante Gabriel , Frasson Antonio , Galimberth Viviana , Sacchini Virgilio , Veronesi Umberto
Published: August 2023

Nos últimos 15 anos o tratamento cirúrgico do câncer de mama foi revolucionado por alguns novos conceitos na história natural destes tumores. A impossibilidade de controlar a doença com uma cirurgia alargada, a identificação de tumores cada vez menores com o uso da mamografia, a possibilidade da "paciente atual" participar da escolha do tratamento, criaram as condições para um tratamento conservador. Os resultados retrospectivos e, especialmente, prospectivos, dos estudos sobre o tratamento conservador têm demonstrado que a terapia de combinação pode fornecer um adequado controle local do tumor. O Trial 1 de Milão, comparando a mastectomia de Halsted versus a QUART(quadrantectomia, dissecção axilare radioterapia), forneceu uma importante contribuição mostrando não existir diferenças na sobrevida global, período livre de doença e recidivas locais entre os dois tipos de tratamento.
Al-insya’ Atholabi Fi Surat Al-Hujurat (Dirasah Tahliliyah Balaghiyah)
Authors: Nadhif Nadhif
Published: August 2023

Some students face difficulties in understanding the meaning of the Quran in the form of insya thalabi with various meanings that vary based on the context of the verse, sometimes a verse with a pattern of commands but the meaning is not an order but advice, prayer or instructions etc. The purpose of this study was to determine the pattern of insya thalabi and its meaning in Surat al-Hujurat. The type of this research is library research, the data sources in this research consist of primary sources in the form of al-Qur'an al-karim surah al-hujurat and secondary sources in the form of books related to the research theme such as interpretation books, balagah and dictionaries. The research data were analyzed using Balagah descriptive analysis. The results showed that there were 34 insya thalabi in the letter al-hujurat, 16 in the form of amr, 9 in the form of nahi, two in the form of istifham, 6 in the form of nida and 1 in the form of tamanni. As for the meaning of 34 insya thalabi, it is divided into two kinds, namely the essential meaning and the meaning of balaghi. The meaning of balaghi in insya thalabi letter al-hujurat is al-tahdid, al-nuskhi, al-irsyad, al-khusi, al-tasyji', al-khabar, al-tahdid, al-taqrir, al-inkar, al-tamanni li al-wuqu'.
СОЦІАЛЬНА ВІДПОВІДАЛЬНІСТЬ СУБ’ЄКТІВ ГОСПОДАРЮВАННЯ: ОБЛІКОВО-АНАЛІТИЧНИЙ АСПЕКТ
Authors: Пацула Ольга Ігорівна
Published: August 2023

У статті досліджено проблеми обліково-аналітичного забезпечення соціальної діяльності в сучасних умовах. Визначено, що ключовою необхідністю є розуміння взаємозв’язку між показниками витрат, які спрямовуються на реалізацію соціальних ініціатив та фінансовим результатом компанії. Відсутність однакових підходів до формування звітності про соціальну відповідальність забезпечує неузгодженість показників і унеможливлює проведення порівняльного аналізу та розуміння чіткості напрямів такої діяльності для користувачів. Обґрунтовано думку, що система обліку повинна забезпечити формування кількісних та вартісних показників у розрізі кожного напряму соціальної діяльності: персонал; охорона довкілля; охорона праці; освітні, мистецькі та культурні проєкти; благодійна діяльність; розвиток регіонів; волонтерство тощо. Періодичність подання та дотримання чіткої стандартної форми соціальної звітності забезпечить можливість здійснення порівняльного аналізу, а проведення так званого соціального аудиту дасть аналітику впевненість у достовірності наведених у звітах даних. Пропонується застосовувати концепцію обліку із залученням підсистеми управлінського обліку, та чітко окреслювати джерело фінансування соціальних витрат. Зокрема, зазначено, що є частина соціально спрямованих витрат, яка носить обов’язковий характер і є систематичними, а є та частина – яка здійснюється час від часу і здійснюється за ініціативою самого підприємства. Важливою характеристикою останніх є те, що вони не беруть безпосередньої участі у створенні доданої вартості, а здійснюються у порядку її споживання, тому їх фінансування повинно здійснюватися в процесі розподілу чистого прибутку. За такого підходу, можливим стане поєднання кількісних та фінансових показників для визначення обсягу та результатів соціальної діяльності, використання механізмів бюджетування для їх планування та прогнозування.
ІНСТИТУЦІЙНО-ПРАВОВІ ОСОБЛИВОСТІ ЛЕГАЛІЗАЦІЇ ЕКОНОМІКИ ТА ПРОТИДІЇ КОРУПЦІЇ В УКРАЇНІ ТА СВІТІ
Authors: Мельник Степан Іванович , Яремчук Ростислав Євгенович
Published: August 2023

У статті здійснено компаративний аналіз для встановлення інституційно-правових особливостей процесів легалізації економіки та протидії корупції низки країн світу для виокремлення основних напрямів удосконалення цього процесу в Україні. Обґрунтовано доцільність модернізації українського інституційно-правового механізму легалізації економіки та протидії корупції відповідно до європейських та світових стандартів, що є передумовою успішної інтеграції держави та сприятиме забезпеченню її економічної безпеки. В результаті проведеного теоретичного аналізу зарубіжного досвіду виокремлено дві домінуючі стратегії протидії корупції та легалізації економіки у світовій практиці. Здійснено компаративний аналіз інституційно-правового механізму легалізації економіки та протидії корупції низки країн світу, що використовують різні антикорупційні стратегії. Розглянуто стратегічні орієнтири, основні завдання та специфіку механізму протидії корупції та легалізації економіки таких країн світу як: Сінгапур, Південна Корея, Китай, Японія, Швеція та Данія. В результаті проведеного компаративного аналізу встановлено основні переваги різних систем та виокремлено ключові елементи, які можна запровадити в українській практиці для удосконалення інституційно-правового забезпечення легалізації економіки та протидії корупції, що сприятиме забезпеченню економічної безпеки та прискорить євроінтеграційні процеси. Визначено інституційні особливості національної системи легалізації економіки та протидії корупції, що реалізовано за допомогою теоретичного аналізу особливостей діяльності, специфіки завдань та повноважень основних антикорупційних та органів протидії економічній злочинності, а саме: Національного антикорупційного бюро України, Національного агентства з питань запобігання корупції та Спеціалізованої антикорупційної прокуратури. На основі результатів проведеного дослідження розроблено основні напрями та сформовано перелік рекомендацій щодо легалізації економіки та протидії корупції в Україні в умовах посилення інтеграційних процесів.
THE FOOD SYSTEM: ESSENCE AND MEASURES TO ENSURE ITS SUSTAINABILITY AT THE COMMUNITY LEVEL
Authors:   National Institute for Strategic Studies, Rusan Vitalii
Published: August 2023

The article considers the essence of the food system, as a system of interconnected elements that interact in a certain way with the external environment and with each other and aim to provide people with food products. Food system issues include the governance and economics of food production, its sustainability, the extent to which we waste food, how food production affects the natural environment and the impact of food on human and population health. The full-scale aggression of the Russian Federation forced a different approach to the formation of food security in the country, its regions and communities. The impossibility of cultivating a large part of agricultural land, interrupted traditional supply chains, rising prices of products, changes in the population of communities, and therefore in food needs, the impact of blackouts on production enterprises, the destruction of processing and storage infrastructure exacerbated the issue of sustainable food supply. The issue of ensuring the sustainable functioning of the food system in the conditions of the challenges of wartime is becoming more and more relevant in the national system of sustainability, which aims to guarantee the safety and continuity of the functioning of the main spheres of life of society and the state before, during and after the onset of a crisis situation. The main measures to ensure the sustainability of the food system of communities have been formed, in particular: ensuring the efficiency of the functioning of producers of agricultural products that carry out their activities on community lands, creating a system of primary and advanced processing of agricultural products capable of satisfying the demand of the community in the form of ready-made food products or semi-finished products, ensuring an effective storage system for agricultural products, ready-made food products and semi-finished products, ensuring an uninterrupted system of supplying food products to the population, personnel support for agricultural production.
SUSTAINABLE SAFE INNOVATIVE DEVELOPMENT IN THE DOMESTIC TERRITORIAL TOURIST DESTINATION
Authors:   Dmytro Motornyi Tavria State Agrotechnological University, Trusova Natalia , Tsviliy Sergiy ,   National University «Zaporizhzhia Polytechnic»
Published: August 2023

The relevance of the problem lies in the disclosure of security aspects of sustainable innovative development of the territory. The purpose of the study is to substantiate a comprehensive approach to finding ways to ensure sustainable, safe, innovative development in the domestic territorial tourist destination based on the assessment of threats and risks and optimization of their management methods to minimize the impact of destructive processes in the tourism industry. Several main threats to the tourism business in the context of interregional cross-border cooperation between Ukraine and EU countries are highlighted. The types of risks of safe innovative development of tourist activity of TTD were identified by the method of expert survey of representatives of tourist operators and travel agencies. The analysis of the results of the expert survey shows the low readiness of the tourist business environment of TTD for the implementation of the risk management system. Optimization methods of risk management of safe innovative development of tourist enterprises in the territorial tourist destination are singled out. The optimization of the structural components of the safe innovative development of tourist enterprises in the territorial tourist destinations of Ukraine is clearly presented. The relevance of the modernization space of TTD in conditions of instability, taking into account the effectiveness of programs of social adaptation of the population to the limitations and possibilities of setting up a system of comfortable and safe life activities, has been established. The main groups of indicators that characterize the tourist suitability of TTD for innovative development as ethnic tourism are presented. A set of priority measures to reduce the negative consequences of destructive processes in the "tourism-environment" system has been formed. The general index of the safe state of innovative development of the tourism industry in the TTD of Ukraine was determined. Relatively homogeneous and adjacent TTDs are grouped in the modernization space of safe innovative development of the country. Further scientific developments make sense regarding the creation of a tourist hub in order to establish information and communication interaction between TTD.
IMPROVEMENT OF INNOVATION AND INVESTMENT APPROACHES TOWARDS SYSTEM AT MANAGEMENT OF LAND (SOIL) RESOURCES BY CIRCULAR AGRICULTURAL ECONOMY
Authors:   State Biotechnological University, Ulko Yevhenii ,   NSC “ISSAR named after O. N. Sokolovsky”
Published: August 2023

The article develops the main conceptual approaches to the management of land (soil) resources in the conditions of the formation of a circular agrarian economy. The need to transform the economic system of the agrarian sector due to the current inability to ensure sustainable management of land (soil) resources and competitiveness of the agrarian sector in the future in accordance with the goals of sustainable development is substantiated. Monographic studies show that unavoidable annual losses due to the presence of land degradation in Ukraine amount to about 24 billion dollars. USA, in particular, 5,5% are direct economic losses of land users and 94,5% are ecological and economic damage (losses) as a result of a decrease in the provision of ecosystem services of lands (soils) for all stakeholders. The role of the agricultural sector in the national economy is summarized and numerical imbalances in innovation and investment activities are revealed. Thus, in 2010–2020 years, the specific weight of the agricultural sector in the country’s GDP was within 2019–2020 years of 7–10%, in terms of gross profit (mixed income) – 15–23%, and in exports of goods and services – 6–21%. However, capital investments in the agricultural sector did not have sustainable growth and did not exceed 10% of the country's economy in 2019–2021 years, or remained almost at the level of 2010 year. At the same time, capital investments in land resources decreased to 0,4% in 2021 year and had a clearly pronounced downward trend. It was found that innovative costs of the agricultural sector are formed by almost 90–100% due to budgetary and own funds of organizations, while in the economy only by 50–60%. It is highlighted that the reasons for this situation of the agrarian sector are their low interest and activity, almost the entrepreneurial sector and private investors do not participate in the financing of innovations. As a result of the research, a cascade scheme of land (soil) resource management was formed for the transition to a circular agrarian economy, which is entrusted with the task of solving problems related to the sustainable development of land use.