bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTATION OF TECHNOLOGY TRANSFER ON THE BASIS OF EVALUATION – INTELLECTUAL PROPERTY READINESS LEVEL
Authors:   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Voitko Serhii , Pasichnyk Vitalii ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Yurchyshyn Oksana ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute»
Published: October 2023

The article is devoted to the theoretical justification and development of the methodology for assessing the intellectual property readiness level (IPRL - Intellectual Property Readiness Level) for commercialization using a step-by-step change of nine levels for a specified object of intellectual property rights (IPR). It is emphasized that the mechanism of using this approach makes it possible to identify unpromising developments for commercialization, to stimulate and speed up procedures for promising ones, and to promote to the market, those that may have a high level of interest of business structures. The importance of building a knowledge economy using the results of research works in university science is outlined. Systematization of scientists' work on the evaluation and selection of commercially suitable ideas for further support of the object of intellectual property rights on the way from the registration of a patent to the start of production of products based on the inventors' ideas has been carried out. The practice of using the system for assessing the levels of technological readiness of the object of intellectual property rights is considered. The composition of each of the nine proposed IPRL levels is defined and the main characteristics of each of these levels are described. The criteria for the promotion of a specific object of innovation with such evaluations as active, normal, passive, "frozen" intellectual property are highlighted. A dependency for determining IPRL is proposed, which provides stakeholders with a quantitative estimate of the existing level of IPRL. Determination of the dynamics of the transition from level to level for the intellectual property portfolio of the organization according to the proposed IPRL assessment allows to assess activity and, if necessary, intensify commercialization. It is noted that the method can be used by institutions of higher education that carry out scientific research and scientific and technical developments. A methodological approach to the process of quantitative assessment of the level of readiness of intellectual property for commercialization using nine levels, and the change of this level over time determines the dynamics of the development of the object of intellectual property rights, is defined as a scientific novelty. The practical significance of the proposed approach is outlined as an opportunity to quantitatively evaluate the process of realizing the concept of commercialization of the results of scientific activity.
DEVELOPMENT OF DOMESTIC INSTITUTIONS OF HIGHER EDUCATION BASED ON THE TRIPLE HEICAL CONCEPT
Authors:   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Kravchenko Maryna , Bronytska Maryna ,   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”
Published: October 2023

The paper is devoted to the studies of the problems of activity and development of higher education institutions in the conditions of the war economy and subsequent post-war reconstruction at a qualitatively new high-tech level. It is emphasized that domestic educational institutions have limited financial autonomy and operate under strict legal restrictions. The regulatory and financial constraints that hold back the prospects for the development of higher education institutions are analyzed. The need for an accelerated transition to the full implementation of the institutional model of the triple helix at the macro level of the country is substantiated. The features of the functioning of the triple spiral model are defined, the specifics of the interaction of the institutional spheres involved in it, as well as the functions of each of them, are outlined. The determining role of universities in ensuring the dynamics of the development of the innovative economy according to the triple spiral model has been proven. Evolutionary models of university functioning are studied. The characteristic features of the university at each stage of evolutionary development are explained. It was noted that the transformation of universities from educational and educational-scientific to educational-scientific-innovative is accompanied by the hybridization of their missions. The concept of a research university is being replaced by the concept of an innovative or entrepreneurial university. The relevance of the entrepreneurial “University 3.0” concept to the needs of the development of the innovative economy is substantiated. On the example of the National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute" and the All-Ukrainian innovation ecosystem "Sikorsky Challenge Ukraine", which is developing on its basis, the experience of the development of domestic higher education institutions as entrepreneurial universities was analyzed. The all-Ukrainian innovation ecosystem "Sikorsky Challenge Ukraine" unites the country’s institutions interested in the development of the Ukrainian innovation economy: universities, scientific institutions, state and local self-government bodies, business companies, foundations, and public organizations. The article identifies the reasons that hold back the development of universities based on this concept, summarizes the obstacles on the way to successful startups, and outlines the ways to solve them.
ASEAN ROLE IN THE DEVELOPMENT OF THE ECONOMY OF SOUTH-EAST ASIA
Authors:   Lviv Polytechnic National University, Ohinok Solomiia , Buryak Yuriy ,   Ivan Franko National University of Lviv
Published: October 2023

The article investigates the role of the Association of SouthEast Asian Nations in the process of forming the economy of the lands of SouthEast Asia. Defining the role and place of multilateral dialogue mechanisms in particular, the ASEAN Regional Forum, in the Southeast Asia on economic issues in the architecture of the economy is a highly important issue of the thesis. It is argued that due to the post-bipolar security uncertainty in Southeast Asia the request to establish a regional security body that would include not only ASEAN member states but also their Asia Pacific dialogue partners and other countries to develop joint collective threat response to economic threats facing the region. The structure of the article is aimed at gaining optimal solution of the set tasks. It allowed to obtain scientific results in the form of conclusions that give a holistic view of the conceptual principles, mechanisms, core directions of ASEAN economic activity in Southeast Asia, specific cooperation patterns between member states of the Association and key non-regional actors in international relations, including Ukraine. For this purpose, the subject limits of research and the use of a wide range of general and special methods are substantiated in the article, which allowed studying the object of research. The study provides a thorough analysis of the scientific level development of the problem, reveals the main trends of modern research on the problems of East Asian economic processes. In the course of the study, the regulatory, axiological and praxeological principles of the Association's functioning were analyzed using the example of the ASEAN Community as a basic economic initiative of the organization, aimed at ensuring the necessary level of cooperation among member states in solving urgent problems. The author of the article draws attention to the fact that in the early 90s of the XX century іn SouthЕast Asia, a number of threats not only of a traditional (conventional) but also to a greater extent non-traditional (transnational/cross-border) nature became actualized. The processes of globalization, the specificity of regionalism, the dynamics of economic processes have led to the appearance of a number of problems and challenges in the field of economy, which the countries of the SouthЕast Asian region have faced. Thus, this study is relevant, as it provides an understanding of the dynamics and main trends of the economic development of the SouthЕast Asian region, in particular, in the field of economic cooperation. For Ukraine, the results of the study open up additional opportunities for establishing friendly and constructive relations with ASEAN member countries.
ТЕОРІЯ АДАПТАЦІЇ БІЗНЕСУ ДО УМОВ НЕВИЗНАЧЕНОСТІ
Authors: Халіна Вероніка , Абєлєнцев Євген
Published: October 2023

Стаття присвячена формуванню теоретичного базису адаптації бізнесу до функціонування в умовах невизначеності. Розглянуто зростання невизначеності з точки зору концепцій світоустрою, а саме, SPOD, VUCA та BANI світу та встановлено чіткий зв'язок позитивної динаміки із ускладненням світового порядку. Проаналізовано підходи до визначення поняття «адаптація» закордонних та українських науковців в період з середини 80-х років ХХ століття до теперішнього часу. Також встановлено, що одним з джерел невизначеності, а також її різновидом, є семантична невизначеність, яка породжується неоднозначними трактовками понять. Крім того сформовано класифікації за різними ознаками категорій адаптації та невизначеності, що надасть можливість обирати відповідні до ситуації види. В результаті підведення теоретичного підґрунтя, а також для вирішення ряду виявлених проблем, сформоване авторське трактування поняття «адаптація», що в подальшому послужить основою для генерування прикладних аспектів адаптації бізнесу до умов невизначеності.
Impact of Artificial Intelligence on Racialized Groups
Authors: Effoduh Okechukwu (Jake)
Published: October 2023

This presentation discusses the impact of artificial intelligence on racialized peoples and groups, especially by legal institutions (courts, police, etc).
PARTISIPASI MASYARAKAT DI SEKITAR HUTAN DALAM PROGRAM PERHUTANAN SOSIAL
Authors: Rosada Ida , Boceng Annas , Azis Erni
Published: October 2023

The purpose of this study was to identify the implementation of the Social Forestry (SF) Program at the HKm Forest Farmer Group in Balusu District, Barru Regency, identify and analyze the level of community participation around the forest in the implementation of the social forestry program at the HKm Forest Farmer Group in Balusu District, Barru Regency and analyze the factors involved influencing the participation of communities around the forest in the implementation of SF programs at the HKm Forest Farmer Group in Balusu District, Barru Regency.This research was conducted. The research location was carried out in Balusu District, Barru Regency, South Sulawesi Province in the SF Program at the KTH HKm Sero and Sarewe Groups. While the time needed to conduct this research is 2 (two) months, namely August to September 2020. The population in this study were all members of KTH HKm in Balusu Subdistrict totaling 82 people, consisting of 45 KTH Sero, and KTH Sarewe. as many as 37 people. The sampling method was carried out by using the census method or taking all members of the HKm forest farmer group in Balusu District.The research data analysis method is using the method of effectiveness analysis, qualitative descriptive analysis, percentage analysis and multiple linear analysis.Therefore, to increase community participation in the management of hkm in Balusu sub-district, new regency, it is hoped that farmer groups need to be more active in assisting the government through the Forestry Service in developing Community Forestry (HKm) development programs in Balusu District, Barru Regency.
EVALUASI KERAGAMAN DAN STABILITAS KARAKTER PERTUMBUHAN DAN PRODUKSI 12 GALUR CALON VARIETAS JAGUNG HIBRIDA
Authors: Nurhana Nanik , Kusmiyati Florentina , Anwar Syaiful
Published: October 2023

Corn is the number two stable crop in the world with increasing demand in line with population growth. The use of superior hybrid corn varieties is one of the solution in meeting the needs of corn throught plant breeding activities. The experimental design used was a monofactor randomized block design (RAK), with the object is 12 prosprective line of hybrid corn varieties from PT Tunas Widji Inti Nayottama (RD 422, RD 471, RD 491, RD 496, RD 551, RD 519, RD 523, RD 536, RD 586, RD 591, RD 602, RD 60), and control varieties is Bisi-18 and P31. The parameters observed included number of plants grown, high of plant, high of ear, lenght of ear, diameter of ear, weight of ear, weight of cob, number of seed rows pear earm number of seed per row, weight of 100 seeds, yield, seed moisture content, physiological maturity, and potential harvest. Variance analysis data and continued with the independent T test. The result showed that 7 corn lines which have the desired properties are RD 422, RD 471, RD 551, RD 519, and RD 603. The level of stability according to the coefficient of diversity, all of the test lines had low stability (uniform), except for RD 491 on the character of anxious weight (29.23%) and RD 602 on the character of the number of seeds per row (39.36%).
Targeting TFH cells is a novel approach for donor-specific antibody desensitization of allograft candidates: an in vitro and in vivo study
Authors: Ma Ning , Wu Wei-Bing , Zhao Xiang-Yu , Xu Lan-Ping , Zhang Xiao-Hui , Wang Yu , Mo Xiao-Dong , Zhang Yuan-Yuan , Zhao Xiao-Su , Sun Yu-Qian , Cheng Yi-Fei , Liu Kai-Yan , Chang Ying-Jun , Huang Xiao-Jun
Published: October 2023

The presence of donor-specific antibodies (DSAs) are associated with graft failure either following HLA-mismatched allogeneic stem cell transplantation or after organ transplantation. Although targeting B cells and plasma cells have been used for desensitization, there have been reports of failure. T follicular helper (Tfh) cells assist B cells in differentiating into antibody-secreting plasma cells. We used haploidentical allograft as a platform to investigate the possibility of targeting Tfh cells to desensitize DSA. The quantities of cTfh cell subsets in allograft candidates were abnormal, and these cells, including the cTfh2 and cTfhem cell subsets, were positively related to the production of anti-HLA antibodies. Ex vivo experiments showed that the cTfh cells of anti-HLA antibody positive allograft candidates could induce B cells to differentiate into DSA-producing plasmablasts. The immune synapse could be involved in the assistance of cTfh cells to B cells in antibody production. In vitro experiments and in vivo clinical pilot studies indicated that targeting cTfh cells with sirolimus can inhibit their auxiliary function in assisting B cells. Ex vivo and in vivo studies demonstrated the effect of sirolimus and rituximab on DSA desensitization compared with either sirolimus or rituximab alone (60%, 43.75%, and 30%, respectively). Our findings provide new insight into the role of Tfh cells in the pathogenesis of DSA production in HLA-mismatched transplant candidates. Our data also indicate that targeting Tfh cells is a novel strategy for DSA desensitization and combination of sirolimus and rituximab might be a potential therapy.
Eligibility criteria: too big, too small or just right?
Authors: Atallah Ehab
Published: October 2023

Not available.
Towards Artificial General Intelligence - A Survey of Hyperdimensional Computing and Vector Symbolic Architectures with Quantum Computing for Multivariate Predictions
Authors: Chibuye Mulima , Phiri Jackson
Published: October 2023

To achieve true artificial intelligence would be to mimic the human brain. Some have espoused that current systems that we call AI today are nothing more than if-else statements. There are other arguments that state that indeed, the act of decision making itself is a bunch of nested if-else statements. However, we note that the human brain and through processes that are far more complicated than that has levels of cognition that far outweigh those of any machines that have been made today. While computing systems perform better at certain tasks than human beings do, they remain inherently specific. Human minds are generally creative and knowledge making entities. In this paper, we explore the current progress made towards achieving Artificial General Intelligence and look at it from the angle of Hyperdimensional Computing and Vector Symbolic Architectures both running with the power of quantum computing. We explain how the achievement of AGI will lead to a much more sustainable form of industrial development as has been touted through advancements towards the Fourth Industrial Revolution.
PERBANDINGAN PENERAPAN METODE PENGAMANAN WEB SERVER MENGGUNAKAN MOD EVASIVE DAN DDOS DEFLATE TERHADAP SERANGAN SLOW POST
Authors: Hijriyannto Budi Hijriyannto
Published: October 2023

Pembelajaran jarak jauh didefinisikan sebagai pangalaman belajar yang fleksibel yang disampaikan melalui penggunaan teknologi informasi dan komputer agar dapat diakses kapan saja, dimana saja, oleh siapa saja. Penerapan pembelajaran jarak jauh di Indonesia sendiri sudah banyak diterapkan oleh lembaga pendidikan yang ada. Salah satunya seperti yang sudah dilakukan oleh Universitas XYZ. Mengingat pembelajaran jarak jauh dilakuakn secara online, maka penting untuk menjaga keamanan web server dari ganguan yang tidak diinginkan.Salah satu ancaman yang dapat menggangu kegiatan belajar mengajar dalam pembelajaran jarak jauh yaitu serangan Slow Post. Slow Post termasuk ke dalam  jenis serangan DoS. Sehingga dalam penelitian ini akan menggunakan metode pengamanan yang biasanya digunakan untuk menangkal atau mengurangi dampak serangan DoS. Metode yang digunakan dalam penelitian ini adalah Mod Evasive dan DDoS Deflate.Hasil dari penelitian ini adalah metode pengamanan yang baik dalam menangani serangan Slow Post. Baik disini dalam artian dimana metode tersebut dapat mengurangi atau menangkal serangan Slow Post yang di tujukan kepada web server. Semoga hasil dari penelitian ini dapat membantu pengelola web server dari pembelajaran jarak jauh pada Universitas XYZ dan dapat dapat dijadikan sebagai salah satu pertimbangan dalam melakukan tindak lanjut mengenai pengamanan web server dari website SPADA di Universitas XYZ.
SISTEM PAKAR DIAGNOSA PENYAKIT PADA IKAN NEMO DENGAN METODE FORWARD CHAINING DI BALAI BESAR PERIKANAN BUDIDAYA LAUT LAMPUNG
Authors: Prasetyo Eko Prasetyo
Published: October 2023

Ikan nemo (Amphiprioninae) merupakan salah satu jenis produk ikan hias air laut yang paling banyak diminati terutama di pasar luar negeri karena bentuknya yang eksotis dan unik Para eksportir ikan hias biasanya membeli ikan nemo dari para nelayan sehingga penyediaannya masih bergantung pada penangkapan alam. Ikan nemo telah berhasil dibudidayakan sejak tahun 2007 oleh Balai Besar Perikanan Budidaya Laut (BBPBL) Lampung. Salah satu masalah utama yang dihadapi Balai Besar Perikanan Budidaya Laut (BBPBL) Lampung adalah penyakit yang menyerang ikan budidaya ini, karena dapat menyebabkan panen yang tidak maksimal dan kematian masal pada ikan. Kurang nya informasi cara penanggulangan penyakit dan sedikit nya pakar ikan nemo menyebabkan pembudidaya mengalami banyak kerugian, oleh karena itu sangat di butuh kan sistem pakar untuk mendiagnosis penyakit pada ikan nemo.Oleh karena itu penulis tertarik membuat aplikasi sistem pakar dengan menggunakan metode Forward Chaining dan certainty factor sebagai metode yang digunakan untuk menghitung  nilai kepastian.                Pengujian dalam penelitian ini yaitu dengan uji akurasi, uji akurasi dilakukan sebagai pengujian akurat sistem yang dibangun. Hal ini dilakukan dengan tujuan untuk mengetahui apakah akurat antara pakar dan sistem pakar, ketepatan uji akurasi. Berdasarkan pengujian akurasi yang dilakukan dengan ketepatan sistem dan seorang pakar, sistem mendapatkan klasifikasi 93.33%  layak untuk digunakan. Pengujian juga menggunakan model pengujian ISO 25010 dengan menggunakan aspek functional, aspek efficiency, dan aspek operability. Dari 25 orang responden yang mengisi kuesioner untuk pengujian aplikasi, semua responden memberikan jawaban kuesioner dengan valid, dengan hasil pengujian aspek funcionality 86,4%, aspek efficiency 82,9%, dan aspek operability 87,6%.
Leadership Characteristics as Predictors of Juran Trilogy Principles and Influence on Leaders’ Business Decisions
Authors: Wakefield Ver-Non T.
Published: October 2023

This research examined the relationships among leadership styles, traits, ethics, and Juran Trilogy principles. A non-probability, purposive sampling approach was used to collect survey data from 91 leaders responsible for influencing organizational quality decisions in industries such as manufacturing, business, healthcare, and others. A correlational research design was used to examine how leadership influences business decisions and if there was a preference for leadership styles over leadership traits and whether ethics and ethical leadership affect these preferences. The results indicate that leadership traits have a significant and positive impact on the components of the Juran Trilogy, whereas leadership and duty ethics have a significant and positive impact on quality. The research findings provide useful information that may assist businesses in developing and growing organizational leaders capable of effectively influencing organizational decisions.
Existential Struggles in Nigeria and Social Movement Theory: Case Study of #ENDSARS
Authors: Ifeoma Charles-Monwuba
Published: October 2023

Existential struggles appear to be unending in developing nations, including Nigeria. Some of the existential struggles lead to citizen agitations and evolve into social movements, some of which have recorded varying success rates. This paper thus seeks to examine #ENDSARS protests as a case study vis-à-vis the social movement theory. It explores the theory to provide meaning to what happened with #ENDSARS, outcomes and recommendations for future social movements or otherwise. Findings indicate that New Social Movement Theory (NSMT) played out effectively during the #ENDSARS protest, with technology driving all the attributes of the social movement theory. As a recommendation, the policymakers must approach issues affecting the welfare and livelihoods of its citizens carefully before it snowballs into agitations like the #ENDSARS protest. Government must balance the need for fiscal responsibility and economic growth with the need to protect the interests of ordinary Nigerians and ensure social stability. Theorists must hereafter review new theories against contemporary realities and technological potential.
Determination of Post-Earthquake Trauma Levels of University Students
Authors: DOKUZOĞLU Gökhan , ÜNALDI Gamze
Published: October 2023

Objactive: The aim of this study is to evaluate the post-earthquake trauma levels of young people exposed to earthquake and to examine the effect of recreational sports activities on their social, physical and psychological recovery. Method: The study will focus on 10 provinces, Kahramanmaraş, Gaziantep, Hatay, Adıyaman, Adana, Osmaniye, Diyarbakır, Kilis and Şanlıurfa, which were affected by the earthquake disaster centered in Kahramanmaraş. A sample group of 275 people from Artvin Çoruh University will voluntarily participate in this study. Trauma level assessment scale and personal information form will be used to collect data. The research was evaluated at the p<0.05 confidence interval. Result: The findings of the study show that there is a significant difference between the excitement limitation and affective configuration sub-dimension of the post-earthquake trauma symptoms scale and the gender variable, and that there is a significant difference between the sleep problem dimension and the class variable (p <0.05). Conclusion: As a result, it is seen that the participants' behavioral problems, emotional limitation, affective structuring and scale total scores are at high levels, while their cognitive structuring and sleep problems are at medium levels.
Effects of Carbohydrate and Caffeine-Based Energy Gel Ingestion on Blood Glucose, Blood Lactate and Performance During Prolonged Cycling
Authors: ULUSOY Yusuf , KOÇAK Fatih
Published: October 2023

The aim of this study was to investigate the effects of carbohydrate and caffeine-based energy gels on blood glucose, blood lactate, heart rate, rating of perceived exertion (RPE), power output, cadence during prolonged cycling exercise.
This research was an experimental study in which 15 competitor cyclists were tested in 3 different conditions. 3 experimental trials in a randomized order, no gel intake and water only use (T1), gel intake every 30 minutes (T2), 1 gel intake 15 minutes before exercise, and gel intake every 45 minutes after first gel intake and 1 carbohydrate + caffeine gel at 75 min (T3). Water use was released within 3 trials. Each exercise trial included 2 hours of cycling followed by 15 min TT. Measurements were made at the beginning, every 30 min, and at the end of the exercise. This research found that energy gels increased blood glucose levels and time trial (TT) performance compared to trials without consuming something. A more frequent gel intake improved blood glucose levels and TT distance. In the TT, blood lactate concentration increased significantly in T3 compared to T1 (p<0.05). Heart rate and RPE did not make a statistical difference (p>0.05). Even though cadence, power output, and TT distance in T3 were not statistically significant, the differences that occur are important in terms of cycling. The research also found no correlation between energy gel feedings and water intake (p>0.05). The results were important for cyclists with the positive effect on endurance performance when energy gels are used in long-term cycling exercises.
A MULTIVARIATE INTERPOLATION APPROACH FOR PREDICTING DRUG LD50 VALUE
Authors: KARADUMAN Gül , KELLECİ ÇELİK Feyza
Published: October 2023

Objective: The present study aimed to develop a multivariate interpolation based on the quantitative structure-toxicity relationship (QSTR) that can accurately predict the oral median lethal dose (LD50) values of drugs in mice by considering five different toxicologic endpoints.
Material and Method: A mathematical model was created using a comprehensive dataset comprising LD50 values from 319 pharmaceuticals belonging to various pharmacological classes. We developed a polynomial model that can predict the range of LD50 values for pharmaceuticals. We employed a technique called two-variable polynomial interpolation. This method allowed us to estimate the approximate values of a function at any point within a two-dimensional (2D) space by utilizing a polynomial equation.
Result and Discussion: The resulting model demonstrated the ability to predict LD50 values for new or untested drugs, rendering it a valuable tool in the early stages of drug development. The Ghose-Crippen-Viswanadhan octanol-water partition coefficient (ALogP) and Molecular Weight (MW) were selected as suitable descriptors for building the best QSAR model. Based on our evaluation, the model achieved an overall success rate of 86.73%. Compared to traditional experimental methods for LD50 determination, this innovative approach offers time and cost efficiency while reducing animal testing requirements. Our model can improve drug safety, optimize dosage regimens, and assist decision-making processes during preclinical studies and drug development. This approach provided a reliable and efficient method for preliminary acute toxicity assessments.
Little evidence for bioaccumulation or biomagnification of microplastics in a deep-sea food web
Authors: Hermabessiere L , Thaysen C , Sherlock C , Choy CA , Rochman CM
Published: October 2023

Microplastic contamination is documented in marine organisms, but little is known about bioaccumulation or biomagnification of microplastics, especially in tissues external to the gastro-intestinal (GI) tract. The objective of this work was to explore microplastic contamination in GI tracts and other tissues (abdomen and tail in crustaceans; mantle in cephalopods; fillets in fishes) of species at different trophic levels sampled in a deep-sea food web in Monterey Bay, CA, USA. The species included are tuna crab Pleuroncodes planipes, market squid Doryteuthis opalescens, northern lampfish Stenobrachius leucopsarus, chub mackerel Scomber japonicus, California halibut Paralichthys californicus, and Chinook salmon Oncorhynchus tshawytscha. After chemical digestion, microplastics in GI tracts were quantified and identified to material type using μ-Raman spectroscopy and in other tissues using pyrolysis-GC/MS. The concentrations of microplastics in GI tracts were significantly different among species, and microplastic contamination was dominated by microfibers. The concentrations of microplastics (mainly polyethylene and polyvinyl chloride) in other tissues also varied among species. A significant positive correlation between body size and plastic concentration in other tissues was observed for halibut only, suggesting bioaccumulation may not be ubiquitous. The trophic magnification factor for microplastics beyond the GI tract was <1, suggesting that biomagnification is not occurring in tissues. However, we did observe evidence for biomagnification of microplastics in the GI tracts. Future studies are needed to better understand these patterns and the mechanisms for translocation, bioaccumulation, and biomagnification of microplastics in aquatic organisms.
Legality without Liberalism: The Rule of Law and the Environmental Emergency
Authors: Foran Michael
Published: October 2023

The rule of law is often said to be a liberal ideal, intrinsically associated with the enlightenment and, being necessary for each, supplying the link between liberalism and constitutionalism. In this paper, that idea is challenged. The rule of law, even in its most “formal” conception embraced by Lon Fuller, cannot be severed from an account of law which is thoroughly infused with moral purpose and value. The specific values which inform this principle are often portrayed as confined to action guidance, restraint of state power, and the protection of individual rights. Framed as such, the rule of law often conflicts with the moral and political obligation of political authority to preserve the conditions necessary for the community to survive and flourish. An alternative conception of the rule of law, rooted in the classical legal tradition, sees no conflict here and can thus provide the intellectual framework needed to explain how inaction on behalf of public authority can be as much of a threat to the rule of law as abusive action. With this in mind, the duty upon the state to respond to threats such as climate change or the COVID-19 pandemic is itself best understood as one arising from the requirements of legality. Analysis of state action or inaction in the face of such threats must thus begin with this duty in mind as a constitutive aspect of the rule of law. The threats posed by the environmental emergency are best viewed by reference to the communal underpinnings of the rule of law. The liberal desire to frame all moral issues in the language of individual rights should therefore be resisted. The framework of an individual right to a liveable climate may be the best way for liberal constitutionalism to frame the climate crises, but it is by no means the only way. Indeed, it is a manifestly impoverished attempt to concretise what can only be understood as a threat to the common good itself, grounded within the needs of the global community as a whole.
PELATIHAN PENGGUNAAN DAN PENGEMBANGAN E-KATALOG PADA UMKM ANGGOTA ASOSIASI RUMAH PENGUSAHA MALANG RAYA (RPMR)
Authors: Nurfauziah Suci , Puspitasari Ayu Febriyanti , Hidayatinnisa Nurul , Dhakirah Sanita , Mustain Kun
Published: October 2023

Banyak UMKM yang lemah terhadap literal digital, apalagi saat ini adalah eranya digital, hampir setiap orang membeli atau mencari informasi melalui internet. Saat ini setiap orang selalu memegang handphone, handphone bukan hanya sekedar bisa menjadi alat komunikasi telepon saja, namun juga sebagai alat berbagi informasi melalui chat dan social media. Begitu juga dengan promosi atau menawarkan produk dengan menunjukkan gambar(katalog). Oleh karena itu, katalog dalam bentuk digital/elektronik sangatlah penting untuk menunjukkan barang/produk yang dihasilkan UMKM. Dengan adanya e-katalog maka UMKM bisa lebih mudah membagikan dan menunjukkan katalognya baik itu secara online ataupun offline. Tujuan dari PPM ini adalah memberi wawasan melalui pelatihan dan pembuatan e-katalog pada UMKM anggota asosiasi Rumah Pengusaha Malang Raya (RPMR). Luaran yang diharapkan dengan adanya PPM ini adalah meningkatnya pengetahuan akan literasi digital dan kegunaan e-katalog oleh UMKM sehingga mampu secara mandiri mengelola promosi secara online.
PEMBERDAYAAN PKK MELALUI KEGIATAN EKONOMI PRODUKTIF
Authors: Fatimah Annisa
Published: October 2023

This activity provide a knowledge sharing related to simple entrepreneurship education and training to the PKK team so that they can become an agents of change for housewives in Urek - Urek, Asrikaton Village - Malang. As is well knhe development of the home industry in Indonesia is absolutely needed during this pandemic. Housewives have a savior potential for their family economic. Therefore, the one way to empowerment the housewives is through various PKK activities,  which is have an objective to improve a welfare of its members with various trainings. The initial step for empowering housewives as contributors to strengthening the community's economy is to provide information, knowledge and skills, which must be carried out in multi aspects, they are community, social, cultural aspects, government policies and marketing potential for them. Entrepreneurial ideas, planning strategies, and marketing continues to evolve into the needs of today's society. The PKM activity program is planned to be carried out in April 2022. This time selection has been coordinated with the PKK Team as a host for this by inviting all parties related to the PKM program. The presence of lecturers and students who are also entrepreneurial practitioners is expected to provide enlightenment and new knowledge that is quite meaningful for all participants.
Pemanfaatan Media Promosi Pemasaran Digital: Studi Pada Rumah Sakit di Kabupaten Malang
Authors: Rahmah Shofi Nur
Published: October 2023

The rapid development of technology in the digital era makes people cannot be separated from gadgets and social media. It needs to be considered by hospitals as health service providers to participate in utilizing digital marketing in promoting their health facilities. This study aims to determine the level of knowledge of the public relation and marketing staff at Mitra Delima Hospital, Malang and carried out an intervention in the form of digital marketing training. This study used a pre-experimental one group research method with pre and post intervention designs without control. The samples in this study were 25 staff of public relation and marketing. The data in this study were analyzed descriptively. The results of this study indicated that the staff’s knowledge about digital marketing after participating in the training increased. It is proved by the comparison of pre and post-test scores that were given.
Pencatatan dan Pelaporan Keuangan dengan Zahir Accounting pada UMKM “Green Laundry”
Authors: Mahardika Tiska Ayu , Nawangsari Nonny Laurencia , Puspitasari Dian , Firdaus Vieka Maharani , Fitriani Niken
Published: October 2023

The purpose of financial recording and reporting activities using Zahir software for MSMEs is to provide a solution for MSMEs, namely Green Laundry in Penjaringan Sari, Surabaya City so that they can process financial data properly using Zahir software. This can improve the performance and productivity of MSMEs, especially in terms of management and accountable financial management. This activity is a form of our dedication to the community to apply the knowledge we have acquired in the Accounting study program, UPN Veterans Jawa Timur. This is related to the problem that there are still many MSMEs that do not realize the importance of well-organized financial records and bookkeeping. Through this activity, it is hoped that it can help MSME entrepreneurs to realize that well-organized financial records and bookkeeping are important. This activity was carried out through three stages, starting with the identification of several MSMEs, then collecting data, and finally recording and reporting finances. The results of this activity are financial reports, namely income statements, balance sheets, and cash flow statements.
MAKING OF LAWN BASED ON RUSSIAN PERENNIAL GRASS VARIETIES
Authors: Yufereva Nadezhda , Shchannikova Maria
Published: October 2023

The article presents the results of seven years research on the making of lawns in the conditions of the North-East of the Non-Chernozem Zone of Russia. Under conditions of natural moistening, the process of formation of single-species and mixed lawns based on varieties of perennial grasses of Russian breeding was studied. Weather conditions affected the quality of lawns. In wet years, the quality of lawns increased, in dry years it decreased. For the making of long-term lawns, it is possible to use the red fescue variety Sigma and the meadow bluegrass variety Vagant, for short-term lawns (two years) — perennial ryegrass Karat and VIK 66. When creating single-species lawns, there were no differences in quality between herbages with the recommended and reduced seeding rate, so it is possible to reduce the seeding rate by 25–33% compared to the previously recommended one, which will reduce seed costs. The quality of single-species lawns was higher and more consistent than that of mixed lawns.
METHODOLOGICAL AND TECHNOLOGICAL ASPECTS OF FEED PRODUCTION IN SIBERIA
Authors: Kashevarov Nikolai , Polyudina Revmira , Grishin Vasiliy
Published: October 2023

For the production of high-quality feed for farm animals, the creation of new precocious and high-yielding varieties adapted to Siberian conditions is of paramount importance. Because of many years of breeding work, varieties of winter rye (Sudarushka), Sudangrass (Krasnoobskaya), meadow clover (Prima, Assol), ordinary beckmannia (Rusalochka), boneless stalk (Flagman), spring rapeseed (SibNIIK 32), soy (Gorinskaya, SibNIIK 9) have been created in the SFNCA of the Russian Academy of Sciences.
CHARACTERISTICS OF MEADOW CLOVER VARIETIES OF DIFFERENT TYPES OF RIPENESS
Authors: LYuBEZNAYa Margarita
Published: October 2023

The results of a comprehensive assessment of varieties of red clover in the collection nursery are presented. To create highly productive varieties of different types of ripeness, the sources of the most significant economically useful traits and properties were identified: tallness, high yield of green mass, leafiness, high dry matter content in green mass.
FORMATION OF MEADOW FARMING IN RUSSIA, MODERN ACHIEVEMENTS AND DEVELOPMENT PROSPECTS
Authors: Kutuzova Anel , Privalova Kira , Teberdiev Dalhat , Otroshko Sergey , Shevtsov Alexey
Published: October 2023

The article reveals the role of V. R. Williams in the scientific justification of the grass-field farming system, as well as in the development of meadow science and meadow farming in Russia. To assess the state of natural forage lands, numerous expeditions were organized for a comprehensive study of hayfields and pastures in zones and regions of the country. The developed methods and technologies for their improvement, used on 10% of the total area of natural forage lands, increased the production of hay and pasture fodder on average in 1986–1990 to 41.5 million tons of fodder units. This proves the great potential for further expansion of the area of improved natural forage lands, as well as high economic efficiency of anthropogenic costs due to the mobilization of various natural factors in the production process. Modern shortcomings in the provision of meadow fodder production are revealed; special equipment, seeds of zoned varieties of herbs, as well as specialists. With further improvement of technologies for improving natural forage lands, it is necessary
Utvikling av profesjonskompetanse: Estetiske læreprosesser i yrkesfaglærerutdanning – En utforskende kvalitativ studie av norske yrkesfaglærerstudenters erfaringer med estetiske læreprosesser i en digital kontekst
Authors: Johannessen Wenche , Iversen Jan Viggo
Published: October 2023

The purpose of this study was to explore how experiences with aesthetic learning processes in vocational teacher education contribute to developing professional competence. This is grounded in theories of holistic experience, creative processes, and the development of professional digital competence. Qualitative data for this exploratory case study was generated in two focus group interviews among 10 teacher students in vocational teacher education, 2nd year of study. Using a thematic content analysis three categories emerged: ‘Encounter and courage’, ‘Creativity and images’, and ‘Digital competence and multimodality’. The results show that the students’ encounter with the aesthetic learning process leads to exploratory and critical thinking with an aesthetic quality. Taking part in this aesthetic learning process has led to experiences with holistic learning and in particular the emotional aspect of learning related.
A Estética do Frio e seu idiomatismo violonístico: uma análise do songbook de Vitor Ramil
Authors: Langaro Teixeira Luan Augusto , Magalhães-Castro Beatriz
Published: October 2023

O presente artigo apresenta uma análise de mecanismos utilizados pelo compositor Vitor Ramil expressos, de maneira extramusical, por meio do ensaio A Estética do Frio, na busca da construção de uma identidade sonora que corrobore a sua proposta estética. A partir do songbook do compositor, seu repertório e transcrições, são analisadas escolhas estéticas e idiomáticas feitas por Ramil enquanto violonista e sua relação com o texto cantado. A pesquisa aponta para uma relação entre os conceitos expressos na Estética do Frio, especificamente na canção Milonga de Sete Cidades, como filtros criativos para a composição das partes de violão e suas especificidades sonoras, as tornando parte indissociável da composição como um todo. Assim, busca-se elucidar a relação entre a construção do seu repertório e as ferramentas técnicas utilizadas na obtenção de uma sonoridade característica inserida numa proposta estética.
Discovery of two novel potyvirus genome sequences by high-throughput RNA sequencing in Aconitum carmichaelii tissue samples
Authors: Choi Dongjin , Rai Megha , Rai Amit , Yamazaki Mami , Hahn Yoonsoo
Published: October 2023

The genus Potyvirus (the family Potyviridae) is the largest group of plant-infecting viruses transmitted by aphids. Through high-throughput RNA sequencing analysis of asymptomatic samples of Aconitum carmichaelii, a significant medicinal herb in Asia, we identified the genome sequences of two RNA viruses, tentatively named Aconitum potyvirus 1 (AcoPV1) and Aconitum potyvirus 2 (AcoPV2). The genomes of AcoPV1 and AcoPV2 encode polyproteins composed of 3,069 and 3,054 amino acids, respectively. Sequence comparisons and phylogenetic analyses established that AcoPV1 and AcoPV2 represent unique, novel members within the genus Potyvirus. The estimated RNA polymerase slippage rates at the GAAAAAA motif, responsible for the production of P3N-PIPO or P3N-ALT trans-frame fusion proteins, were 0.79% in AcoPV1 and 1.38% in AcoPV2. The RNA reads of AcoPV1 and AcoPV2 were predominantly found in the leaf and flower tissues, indicating potential feeding preferences of vectors for these viruses. These findings demonstrate the effectiveness of high-throughput RNA sequencing in not only uncovering novel potyviruses, but also in elucidating their genomic dynamics within host plants.
Endowing improved osteogenic activities with collagen membrane by incorporating biocompatible iron oxide nanoparticles
Authors: Li Zheng , Zhang Yunyang , Ye Qing , Wang Lei , Chen Hui , Xu Chenhui , Wang Peng , Sun Jianfei
Published: October 2023

Introduction: Collagen-based scaffolds, renowned for their exceptional biocompatibility, have garnered attention as promising scaffolds for advancing bone tissue regeneration. Nevertheless, these scaffolds possess inherent limitations, such as notably compromised osteo-conductivity and osteo-inductivity.

Methods: Our study focused on enhancing the mechanical properties and osteogenic bioactivities of bovine-derived collagen membranes (CMs) from the Achilles tendon by incorporating FDA-approved iron oxide nanoparticles (IONPs), termed as IONP-CM. Three types of IONP-CMs (IONP-CM-0.5, IONP-CM-1, and IONPCM-1.5) were constructed by altering the amounts of feeding IONPs.

Results: Surface topography analysis demonstrated comparable characteristics between the IONP-CM and neat CM, with the former exhibiting augmented mechanical properties. In vitro evaluations revealed the remarkable biocompatibility of IONP-CMs toward mouse calvarial pre-osteoblast MC3T3-E1 cells, concurrently stimulating osteogenic differentiation. Mechanistic investigations unveiled that the osteogenic differentiation induced by IONP-CMs stemmed from the activation of the Wnt/β-catenin signaling pathway. Furthermore, in vivo bone regeneration assessment was performed by implanting IONP-CMs into the radial defect in rabbits. Results derived from micro-computed tomography and histological analyses unequivocally substantiated the capacity of IONP-CMs to expedite bone repair processes.

Discussion: IONP-CMs emerged as scaffolds boasting exceptional biocompatibility and enhanced osteogenic properties, positioning them as promising candidates for facilitating bone tissue regeneration.
“I want to be there for my children”: fatherhood, diabetes and temporality among Peruvian men
Authors: Pesantes M. Amalia , Ferrazza Isabella , Miranda J. Jaime
Published: October 2023

Introduction

Living with a chronic condition is a challenging experience, as it can disrupt your capacity to function and fulfill social roles such as being a father. Fatherhood constitutes an important component of masculinity that has not received significant attention in studies aimed at understanding the role of gender norms in health-related behaviors. Fatherhood refers to the set of social expectations placed on men to provide, protect, and care for those considered his children. Our paper aims to show the importance of understanding men’s perspectives around fatherhood and its relevance for staying healthy.

Methods

In-depth semi-structured interviews with men living with Type 2 diabetes in Peru to explore their experiences with diabetes management.

Results

Eighteen Peruvian men, diagnosed with Type 2 diabetes for at least one year and with ages between 27 and 59 years old were interviewed. They had an average of three children each and were all insured under the national insurance plan aimed at low-income groups in Peru. Their accounts described their concern of not being able to fulfill their roles as fathers as a result of their condition. They mentioned the importance of being physically and emotionally present in the lives of their children, taking care of them, and being an example. These concerns varied depending on the age of their children: those with younger children were more preoccupied with ensuring they stayed healthy. Temporality provides a relevant analytical approach to understand the interplay of fatherhood and motivation for diabetes management.

Discussion

Our study advances the research around the intersection between health and gender norms and argues that a more nuanced understanding of the construction of masculinity and the relevance of fatherhood in the lives of men could be useful to design and identify better health promotion strategies tailored to men with diabetes.