bluuebunny/crossref_metadata_2025 huggingface dataset:
Cerebrospinal fluid biomarkers for the subtle differentiation of neurodegenerative diseases and psychiatric disorders: A systematic review with network meta-analysis
Authors: Wang Ya-Ting , Feng Si-Tong , Chen Bin , Lei Lan , Zhang Yi
Published: June 2023

Background and purpose
Cerebrospinal fluid (CSF) biomarkers are used to identify or detect the condition of multiple neurodegenerative diseases, even psychiatric disorders. However, discordant results between clinical trials failed to meet the expectations of identifying neurodegenerative diseases and psychiatric disorders. We conducted this systematic review and network meta-analyses to investigate the CSF biomarkers in neurodegenerative diseases and psychiatric disorders.
Methods
Studies before July 2021 were searched based on databases. We included clinical trials that compared the CSF levels of these biomarkers (Aβ1−42, tau, p-tau181, and α-synuclein) between the healthy controls, neurodegenerative diseases, and psychiatric disorders. We conducted traditional pair-wise analysis and network meta-analysis to evaluate the evidence concerning these CSF biomarkers between these neurodegenerative diseases and psychiatric disorders.
Results
This network meta-analysis included 117 studies with 25210 patients to investigate the CSF biomarkers in multiple neurodegenerative diseases and psychiatric disorders. For CSF Aβ1−42 levels, there were no statistically significant differences between these groups in network analysis. Regarding CSF t-tau and p-tau181 levels, statistical significance was observed in the comparisons between AD and other diseases, e.g., ALS. Regarding CSF α-synuclein levels, statistical significance was observed in several comparisons, e.g., AD vs. ALS.
Conclusions
We identified that CSF Aβ1−42, t-tau, and p-tau181 might be promising markers distinguishing AD from other neurodegenerative diseases and cognitive impairment. It is conflicted that CSF α-synuclein acts as the marker for diagnosing neurodegenerative diseases and predicts the presence of psychiatric disorders.
Identification of post-translational modifications of milk and whey proteins with different structures
Authors: Rodzik Agnieszka , Railean Viorica , Pomastowski Paweł , Buszewski Bogusław , Szumski Michał
Published: June 2023

Post-translational modifications (PTMs) regulate cellular processes, and any disruption of PTMs leads to abnormal activity of biological processes, and therefore diseases. The main goal of the present research was focused on developing a rapid analytical method for identifying PTMs in milk (β-casein) and whey (β-lactoglobulin) proteins that differ by structure and composition; the chosen proteins are considered the richest source of nutrients and functional components. The classical in-gel protein digestion method and protein digestion in a microreactor (μ-IMER) method has been performed. In addition, ZipTip pipette tipscontaining C18 reverse phase media were used for both methods to concentrate and purify peptide samples; they also aimed to determine the effect of such a prepared sample on the improvement or deterioration of the sequence coverage result. As support for the preparation of the microreactor, a monolithic copolymer synthesized from GMA and EDMA was used. Subsequently, surface modifications were carried out to attach the enzyme with the highest efficiency. The efficiency of the prepared microreactor was evaluated under HPLC chromatographic conditions using a small-molecule trypsin substrate (BAEE). The obtained hydrolysates from the microreactor and the classical digestion in solution method in the presence of ZipTip pipette tips and without were analyzed by MALDI-TOF MS.
Silicon nitride optical waveguide parametric amplifiers with integrated graphene oxide films
Authors: Moss David
Published: June 2023

Optical parametric amplification (OPA) represents a powerful solution to achieve broadband amplification in wavelength ranges beyond the scope of conventional gain media, for generating high-power optical pulses, optical microcombs, entangled photon pairs and a wide range of other applications. Here, we demonstrate optical parametric amplifiers based on silicon nitride (Si3N4) waveguides integrated with two-dimensional (2D) layered graphene oxide (GO) films. We achieve precise control over the thickness, length, and position of the GO films using a transfer-free, layer-by-layer coating method combined with accurate window opening in the chip cladding using photolithography. Detailed OPA measurements with a pulsed pump for the fabricated devices with different GO film thicknesses and lengths show a maximum parametric gain of ~ 24.0 dB, representing a ~ 12.2 dB improvement relative to the device without GO. We perform a theoretical analysis of the device performance, achieving good agreement with experiment and showing that there is substantial room for further improvement. This work demonstrates a new way of achieving high photonic integrated OPA performance by incorporating 2D materials.
Schwarze Frauen als mehrdimensional diskriminierte Romanfiguren in der kolumbianischen Gegenwartsliteratur
Authors: Homann Florian
Published: June 2023

Mit dem Ansatz der Intersektionalität wird die Situation der Women of Color und deren literarische Repräsentation durch eine Lektüre zweier Romane der kolumbianischen Gegenwartsliteratur fokussiert, die konkret untersucht, wie die alltägliche soziale Benachteiligung mit der Überschneidung mehrerer Kriterien der Ausgrenzung der Protagonistinnen of Color dargestellt und so die mehrdimensionale Diskriminierung dieser Personengruppe sichtbar gemacht wird. Die Protagonistinnen der im 21. Jahrhundert spielenden Romane erfahren verschiedene Formen von sowohl physischer wie auch struktureller Gewalt, was als paradigmatisch für noch heute herrschende soziale Hierarchien und Differenzen verstanden werden kann. Der Roman "Hündin" (2020 [2017]) von Pilar Quintana macht über die intern fokalisierte Darstellung der Erinnerungen der marginalisierten afrokolumbianischen Protagonistin gesellschaftliche Stereotypen sichtbar, was zu einer teils kontroversen Rezeption geführt hat; die Herangehensweise, das Werk unter dem Blickwinkel der Intersektionalität zu lesen, lässt jedoch die Beschreibungen der prekären Umstände als Offenlegung bestehender Machtverhältnisse deuten, um neben diesen Machtstrukturen die traditionelle Rolle der Frau in der Gesellschaft kritisch zu hinterfragen. "Die Kosmetikerin" (2019 [2015]) behandelt die Lebensumstände verschiedener Frauen im Kontext der 'estratificación' als gesellschaftliche Schichtung in Kolumbien und schildert vorrangig das Leben einer Protagonistin of Color in äußerst prekären Situationen, wobei das Element der Gewalt als omnipräsentes Motiv in der kolumbianischen Erzählliteratur deutlich wird.
Schwarz, schwanger und selten sicher : über unheimliche Automatenszenen und serpentinenförmiges Erzählen in Olivia Wenzels "1000 Serpentinen Angst" (2020)
Authors: Huber Sabrina , Villinger Antonia
Published: June 2023

Der Artikel zeichnet im Anschluss an eine kulturwissenschaftlich ausgerichtete Erzähltheorie an Olivia Wenzels Roman "1000 Serpentinen Angst" (2020) die im Text entworfenen Familienbeziehungen nach. Fokussiert wird, wie die Erzählerin sich über das Erzählen selbst mit ihrer eigenen intersektionalen Identität als Schwarze ostdeutsche queere Frau auseinandersetzt. In Rückgriff auf zentrale Forschungsbeiträge zum Konnex von Gender, Erinnerungsstrukturen und Erzähltextanalyse wird erstens gezeigt, dass durch die Erzähltechnik Situationen und gesellschaftliche Herausforderungen wie z.B. auch die staatlich-systematischen Ungleichheitsbehandlungen im Falle von Personenüberwachung akzentuiert werden, mit denen die Frau konfrontiert wird. Wenzels Erzählweise lässt sich als serpentinenartiges Erzählverfahren beschreiben, das in Erzählschlaufen und über narrative Umwege funktioniert. So wird gerade durch die Darstellungsweise des Romans deutlich, welche Schwierigkeiten in der persönlichen wie kulturellen Verortung der Figur liegen. Der Text wird zweitens als Erinnerungs- und Familienroman gelesen. Die intersektionale Identität der Erzählerin lässt sich dabei über die verschiedenen Lebensgeschichten ihrer Familienangehörigen, und besonders in der Abgrenzung von diesen, wie auch über ihre eigene Schwangerschaft rekonstruieren. Es zeigen sich übergenerationale und sich gegenseitig bedingende Faktoren für Ausgrenzungen und Stigmatisierung, welche Interdependenzen zwischen Geschlecht, Körperlichkeit, Öffentlichkeit, Identität und nationaler Zugehörigkeit offenlegen.
Ungleichheitssensitive Geschichten vom Land : über Dorf und Provinz als literarische Räume der Darstellung und Reflexion von Intersektionalität
Authors: Barthold Willi Wolfgang
Published: June 2023

Ausgehend von der Frage nach literarischen Darstellungskonventionen, die zu verschiedenen historischen Zeitpunkten als Medien der Beobachtung und Reflexion von Intersektionalität und interdependenten Herrschaftsverhältnissen dienen konnten, untersucht der Beitrag das Erzählen 'vom Dorf' und 'der Provinz' als Mittel der Narration von sozialer Ungleichheit. Spätestens seit dem 19. Jahrhundert intensiviert sich eine kulturelle Stadt-Land-Dichotomie, aufgrund derer das 'Ländliche' in Abgrenzung zur urban geprägten Moderne als das rückwärtsgewandte, hierarchisch schwächere 'Andere' wahrgenommen wird. Die Zugehörigkeit zu einem ländlichen oder städtischen Umfeld entwickelt sich daher zur 'Ungleichheitskategorie', die im intersektionalen Zusammenspiel mit anderen Differenzfaktoren auftreten kann. Zugleich ist 'das Dorf' als sozialer Raum konventionell durch eine strikte Einteilung von Menschen in die Kategorien 'Einheimische' und 'Fremde' geprägt und produziert auf Basis strenger Normvorstellungen in besonderem Maße soziale Zuschreibungen der Nichtzugehörigkeit, die wiederum mit Diskriminierungskategorien wie Geschlecht, ethnische Herkunft, ökonomischer Status etc. verwoben sein können. In der literarischen Dorfgeschichte bzw. dem 'Provinzerzählen' vom 19. Jahrhundert bis in die Gegenwart dient der rurale Raum daher auf vielfältige Weise als Ort der Darstellung und Reflexion intersektionaler Formen der Diskriminierung und Ungleichheit. Demonstriert wird dies durch eine Untersuchung von Berthold Auerbachs Dorfgeschichte "Des Schloßbauers Vefele" von 1843 und Maja Haderlaps Roman "Engel des Vergessens" aus dem Jahr 2011.
"Dieser Kohn ist gefährlich" : Jewishness, Sexualität, Disability und Gender in Alfred Lichtensteins Figur Kuno Kohn aus intersektionaler Perspektive
Authors: Hellmann Liesa
Published: June 2023

Klein, schwach, mit einem deformierten Rücken und einer aus heteronormativer Perspektive devianten Sexualität - auf den ersten Blick verkörpert die literarische Figur Kuno Kohn gängige antisemitische Stereotype zu Beginn des 20. Jahrhunderts. In den frühen 1910er-Jahren entworfen und in einer Vielzahl von Texten unterschiedlicher Gattungen ausgebildet, ist Kuno Kohn die Schlüsselfigur in Alfred Lichtensteins (1889–1914) Werk und zugleich Projektionsfläche für die wirkmächtigen Differenzkategorien Jewishness, Sexualität, Disability und Gender. Dichotome Kategorisierungen können die Komplexität der Figur nicht erfassen: Von Lichtenstein als grotesk überzeichnete Figur angelegt, laufen in ihr Binäroppositionen wie jüdisch/nicht jüdisch, homosexuell/heterosexuell und behindert/nicht behindert ins Leere. Statt zu versuchen, die Ambivalenzen, Vielschichtigkeiten und scheinbaren Widersprüche der Figur aufzulösen, rückt der Beitrag sie in einer intersektionalen Figurenanalyse in den Mittelpunkt. Dies lenkt den Blick auf die diskursive Co-Konstruktion der Differenzkategorien auf der Folie des Figurenkörpers und offenbart das subversive, queere Potenzial, das der Figur eingeschrieben ist.
Intersektionale Verstrickungen in Jackie Thomaes Roman "Brüder" und deren Bedeutung für eine kulturtheoretische Fundierung der diversitätsorientierten Deutschdidaktik
Authors: Dannecker Wiebke
Published: June 2023

Am Beispiel des zweiten Romans von Jackie Thomae "Brüder", der 2019 auf der Shortlist für den Deutschen Buchpreis stand und für den sie 2020 mit dem Düsseldorfer Literaturpreis ausgezeichnet wurde, wird untersucht, inwiefern eine intersektionale Betrachtung des Romans eine Reflexion der Darstellung unterschiedlicher Differenzkonstruktionen und ihrer Verstrickung anzuregen vermag. Außerdem stellt der Beitrag zur Diskussion, inwiefern eine vertiefte Auseinandersetzung mit Jackie Thomaes Roman "Brüder" im Literaturunterricht eine kritische Reflexion des Erzählten im Sinne einer 'Critical Narrative Literacy' initiieren kann. Davon ausgehend wird ein Modell einer Diversitätsorientierten Deutschdidaktik entwickelt, dem eine kulturtheoretische Fundierung im Sinne der Intersektionalitätstheorie zugrunde liegt.
Does transitioning away from GHG emitting companies hinder the capacity of banks to create shareholder value?
Authors: Nkwaira Chekani , Margaretha van der Poll Huibrecht
Published: June 2023

This article investigates the capacity of banks to create shareholder value amidst regulators and stakeholders’ growing demands for reductions in financing to greenhouse gas emitting companies. The purpose of the study is to evaluate the shareholder value creation capacity of banks amidst transition risks resulting from reductions in loans from high greenhouse gas emitters. The study compares reductions in balance sheet corporate loans to returns on equity from income statements. The comparison is done for periods during which interest rates move downwards as a way of stress testing banks’ capabilities to generate shareholder value. A risk-return analysis is conducted to determine the rate of change in risk compared to shareholder value. A hypothesis-testing focus is used to test a value-creation proposition concerning the rate of change in corporate loans and return on equity. The results of the study strongly suggest that banks can create shareholder value when faced with loan reductions to high greenhouse gas emitting companies, even within constrained repricing conditions such as negative interest rate movements. Of the cases analyzed 88% have a similar outcome of value creation, which is supported by a rejection of the null hypothesis at p-value ≤ 0.05, justifying statistical significance. Furthermore, 53% of the changes in return on equity is explained by the changes in loans to greenhouse gas emitting companies. The study concludes that banks could still create shareholder value if they reduce funding towards high greenhouse gas emitting companies, provided they devise prudent strategic portfolio tilts in assets.
Assessment of Knowledge and Rate of Service Uptake of Community Based Health Insurance among Traders in Akpan Andem Market, Uyo, Akwa Ibom State, Nigeria
Authors: Charles Odima
Published: June 2023

Community Based Health Insurance (CBHI) is a form of micro health insurance, which is a health insurance targeting low-income people. The specific feature of CBHI is the community involvement in driving its setup and in its management. Traditional CBHI models are small, voluntary, and often include the pooling of health risks and funds within a community. In Nigeria, many CBHI schemes have had limited success, suffering from low membership levels, and having issues such as regressive financing, poor or lack of involvement amongst scheme members amongst others. The study assessed the level of CBHI knowledge and rate of service uptake of CBHI among the traders. 300 Questionnaires were administered to the traders by face-to-face interview which gave the respondents the opportunity to respond to both the structured and open-ended questions. Inferential statistical tests were used to test the various research hypothesis that arose from the research questions in the study. Various statistical tests such as Chi-square, comparison of column proportions, correlational tests, and multiple regression were used. The result shows a mean knowledge score of 33.79 ± 3.22 with their scores ranging from 25 – 42. 2%. There was no significant relationship between knowledge level and service uptake (p = 0.351). Findings from this study noted that although awareness is poor, a good quota of the participants (79%) still have overall good knowledge of CBHI schemes. Hence, it will be beneficial to leverage on this concretize more efforts towards encouraging people to enrol with the CBHI schemes. Keywords: Community Based Health Insurance, Community Involvement, Voluntary, Health Risk, Regressive Financing, Inferential Statistics, Knowledge Level, Service Uptake.
Adherence to Current HIV Testing Protocols in the Northwest Region of Cameroon: Facilitators and Barriers
Authors: Nshom Emmanuel
Published: June 2023

Prior to the release of the current HIV testing recommendation on retesting for verification (RFV), the Cameroon Baptist Convention Health Services (CBCHS) established 0.5% misdiagnosis and inappropriate ART treatment among ART clients in Northwest and Southwest regions. This study aimed at assessing adherence to HIV testing guideline and issues involved. This cross-sectional study was conducted at 27 purposefully selected sites where participants consented and anonymously completed a questionnaire containing questions on their knowledge and practice on RFV, challenges and facilitators. Records of clients who tested HIV positive in 2021 were reviewed to confirm RFV. Data was analysed for frequencies and proportions. A total of 25(93.6%) facilities had the minimum two laboratory staff, most (93.8%) had a minimum training at diploma level and had two or more years of work experience (91.7%). The staff knowledge was averagely 81% accurate on HIV testing algorithm, 79% on RFV and 63% on practice. The main facilitators of RFV were availability of rapid test kits (46%) and trained staff (10%) while bottlenecks were limited test kits (34%) and refusals (28%). Second event testing was performed for 92.5% (1525) of cases, of whom 93.4% was by another tester. Most independent testers knew the results of the first event test before conducting the second event test. Cases of documentation of second event testing without conducted it were reported. Staff were trained and knowledgeable on RFV, but the practice was low. More training and supervision are required for improvement on adherence to protocols for RFV. Keywords: ART, Adherence, Misdiagnosis, Retesting for verification, PMTCT.
Adherence to Self-care Practices among Diabetes Mellitus Patients at a Tertiary Hospital in Eastern Uganda
Authors: Kiruyi Samuel
Published: June 2023

Adherence to self-care practices among diabetes mellitus patients is vital in achieving optimal glycemic control and delaying the progression of the disease complications. There is limited information regarding diabetes self-care among diabetic patients in Eastern Uganda, where the disease is most prevalent. The aim of this study was to determine the level of adherence to diabetes mellitus self-care practices and the associated factors among adult diabetic outpatients at a tertiary hospital in Eastern Uganda. A cross-sectional study was conducted at Mbale Regional Referral Hospital in Eastern Uganda between September and October 2020, on a sample of 156 diabetic patients recruited through systematic random sampling. A structured questionnaire was used to collect data through self-report. Descriptive and Logistic regression analyses were conducted using STATA version 15.0, and a 5% level of significance. Most of the study participants were female (63.8%) with an average age of 52.3 years (SD 13.8). The prevalence of adherence to self-care was 36.5%. The factors associated with adherence to self-care were good diabetes knowledge (AOR=2.5; 95% CI= 1.2-5.3, p = 0.016), and high self-efficacy (AOR=3.9; 95% CI= 1.8 – 8.7, p = 0.001). Less than half of the patients attending the diabetic clinic at Mbale Regional Referral Hospital in Eastern Uganda adhere to self-care practices. Patients ought to receive comprehensive, consistent, and contextualized diabetes education to enrich their knowledge, as well as a boost of their self-efficacy through interventions like counseling, positive feedback, role models, and peer education. Keywords: Diabetes, Self-care, Adherence, Eastern Uganda, Prevalence, Factors associated.
Retesting of Patients Receiving Antiretroviral Treatment at HIV Care and Treatment and Prevention of Mother-To-Child HIV Transmission Sites in Cameroon
Authors: Nshom Emmanuel Mboh
Published: June 2023

The World Health Organization recommends retesting of newly diagnosed HIV cases for verification of results prior to antiretroviral therapy (ART) initiation. This study aimed at ascertaining the HIV status of clients on lifelong ART. We tested 25% of ART clients in 6 care and treatment (C&T) sites and all HIV-positive women receiving ART in 22 prevention of mother-to-child HIV transmission (PMTCT) sites in Northwest and Southwest regions. Testing was proposed consecutively to clients in group education sessions during ART refill visit until the sample size was achieved. Individual counselling was provided to clients who opted to be retested. Testing was with Determine HIV-1/2 and First Response rapid tests and further testing was with DNA-PCR. Clients with negative test results were counseled to discontinue ART. Results were analyzed comparing misdiagnosis at ART and PMTCT sites. A total of 4526 ART clients were retested for HIV; 3914(86.5%) from ART and 612(13.5%) from PMTCT sites. Female participants dominated (79%) and the median age was 39 years. Higher proportions of clients retested at PMTCT sites were negative with both tests (0.8% vs 0.1%) and had discordant results (1.1% vs 0.4%) than at ART sites. All 32 clients with negative or discordant results were tested with DNA-PCR and 22(0.5%) were negative; 11(0.3%) in ART and 11(1.8%) in PMTCT sites. HIV positive status was confirmed for 99.5% of clients retested, with a lower rate at PMTCT (98.2%) than C&T (99.7%) sites; meaning misdiagnosis and inappropriate ART treatment was more likely at PMTCT. Adherence to recommendation for HIV retesting for verification will reduce inappropriate treatment. Keywords: HIV, Retesting, Misdiagnosis, Care and Treatment Centre, PMTCT, Cameroon
Vestir para ganar: moda y campañas electorales en América Latina
Authors: Sábada Teresa , Ambás Gabriela
Published: June 2023

La revolución digital ha irrumpido con fuerza en las campañas electorales y ha cambiado los paradigmas tradicionales de la comunicación política al insertar nuevos actores que quitan el protagonismo habitual de los partidos políticos como principales actores de las campañas. Así, las campañas hoy en día las hacen ciudadanos anónimos en las redes o grupos organizados en torno a una causa. Este trabajo pone la atención sobre un nuevo factor para las campañas – la moda - y estudia los casos de tres campañas en Latinoamérica donde la moda ha tenido un papel relevante. El artículo desarrolla un marco teórico donde se pueden observar las relaciones entre moda y política, y su poder simbólico y comunicativo. Desde ahí se exploran, mediante el estudio de casos, dos ámbitos donde el juego de la moda es importante para las campañas: 1) el simbolismo de la moda usado en campañas, como con la falta de corbata en el atuendo de Gabriel Boric o los zapatos rojos de Guillermo Lasso, y 2) el uso de la influencia y de los fashion influencers, como en el caso de la mega influencer Mariana Rodríguez, esposa del gobernador elegido en Nuevo León, y su papel en la campaña. Las conclusiones de este trabajo señalan el papel de la moda en la política en el contexto digital, y abren posibilidades nuevas tanto para investigadores como para los expertos en campañas electorales, reforzando la idea de que, para ganar las batallas de la opinión pública, la moda puede ser un elemento más relevante que los discursos.
Gestión de la reputación online en los hospitales públicos españoles. Un análisis cuantitativo
Authors: Medina Aguerrebere Pablo , Medina Eva Medina , González Pacanowski Toni
Published: June 2023

Los hospitales públicos españoles hacen frente a una situación cada vez más complicada debido a los presupuestos limitados, las nuevas exigencias de los pacientes y la expansión de los grupos hospitalarios privados. Para hacer frente a este desafío y reforzar sus posicionamientos estratégicos en el mercado sanitario, algunos hospitales públicos han  implementado estrategias de  comunicación corporativa basadas en el uso de las redes sociales. Este artículo tiene como objetivo analizar cómo los hospitales públicos españoles utilizan Facebook, Twitter, Youtube así como sus webs corporativas para promocionar sus marcas y reforzar sus posicionamientos estratégicos. Para ello, llevamos a cabo una revisión de la literatura sobre comunicación de salud, y a continuación recurrimos a 48 indicadores para analizar cómo los 100 mejores hospitales públicos españoles utilizaban sus sitios web y las tres redes sociales citadas para promocionar sus marcas. Concluimos que la mayoría de los hospitales públicos recurrían a sus sitios web corporativos para difundir contenidos periodísticos; utilizaban Facebook y Twitter para publicar información visual sobre el hospital (logotipo, videos, etc.); y recurrían a Youtube para describir tratamientos médicos y protocolos internos.
Analysis of methods for improving the efficiency of “Iceberg” gas air coolers
Authors: Arslanova Alsu , Farukhshina Regina , Khatmullina Rimma
Published: June 2023

Russia has the largest volume of natural gas reserves in the world. Recoverable natural gas reserves amount to about 67 trillion cubic meters, according to the Ministry of Natural Resources and Environment of the Russian Federation for 2023. In recent years, the development of the Unified Gas Supply System has been growing rapidly. Since 2021 the Government of the Russian Federation has been actively introducing draft laws and regulations related to the scaling of the country’s gasification. In June 2021 came out the Federal Law No. 184-FZ, which instructed the Government of the Russian Federation to adopt regulations aimed at implementation of provisions of free gasification of the country [1]. In September 2021 there was issued Decree No. 1547, [2] approving the new Rules for connecting gas-using equipment and capital construction facilities to gas distribution networks, which introduces the concept of pre-gasification. It is worth noting that new gas mains, compressor stations (CS) are put into operation, active reconstruction of the existing shops with exhausted gas compressor units (GCU) is carried out. One of the most urgent issues of the gas industry today is the efficient use of energy resources. Besides using the energy of flue gases from gas turbine drive of GPA, energy at gas throttling at gas distribution stations and other methods of energy saving, the significant role is played by the effective operation of air coolers of gas (ACG), the operation of which affects the reliable transportation of gas in the main gas pipeline (MG). The paper analyzes the methods of technical condition of gas air cooling devices of “Iceberg” type operated at the production site of the booster compressor station of “Gazprom Dobycha Nadym” LLC. The thermal efficiency of air coolers with all fans turned on and off was determined for the coldest and hottest months of the year. The electric energy savings of the frequency controlled drive (VFD) were calculated.
Analysis of Consumers Rational and Emotional Motives in Making Purchases to Improve Marketing Strategy
Authors: Wibowo Aldrian , Barkah Cecep Safa'atul , Chan Arianis , Tresna Pratami Wulan
Published: June 2023

This research was conducted to analyze the rational and emotional motivation of consumers to make purchases/visit Colada Cafe. Those consumer motivations are rational buying motives and emotional buying motives. The results of this study will be used as a basis for making decisions to improve the marketing strategy carried out by Colada Cafe so that it can compete with competitors. This research was conducted using quantitative research methods with descriptive analysis techniques. Samples from this method were taken using simple random sampling. The sample in this study was 90 Colada Cafe consumers. Based on the data obtained, it can be concluded that the marketing strategy Colada Cafe should do is expanding parking lots, improving promotional methods that not only show the interior but also show prices, promos, taste testimonials, menu variations, good service, strategic locations, and appetizing product displays. In addition, Colada Cafe must improve the quality of the products served to consumers.
Reconciliation of the GTAP and Household Survey Data
Authors: Ivanic Maros
Published: June 2023

This paper presents a method that was employed in order to make the available fourteen household income survey data sets compatible with the data in the GTAP version 5 data base. The first step of the method was the imputation of the unobservable returns to GTAP factors from the reported data. The second step was the reconciliation of the two data sets so that their joint totals would be identical. The paper does not claim to be the final word on either data imputation or reconciliation; instead it works through the various issues encountered in the process, proposes solutions to them and leaves it to the reader to judge the validity of this methodology.
Preparation of leonardite powder-embedded calcium alginate beads and adsorption of Safranin-O dye
Authors: Ozdemir Nihan Canan , Saleh Mohammed , Bilici Zeynep , Arslan Hudaverdi , Dizge Nadir
Published: June 2023

In this study, calcium alginate (Ca-Alg) beads were mixed with leonardite powder to prepare leonardite-embedded calcium alginate (Leo-Ca-Alg) beads. The prepared Leo-Ca-Alg beads were utilized for the adsorption of the Safranin-O dye. Leo-Ca-Alg beads were characterized by X-ray diffraction, Fourier transform infrared, and scanning electron microscopy before and after the adsorption process. The effects of pH, adsorbent dose, initial dye concentration, and contact time on the adsorption of Safranin-O dye onto Leo-Ca-Alg beads were investigated. The optimal condition was achieved at a pH value of 8.0, an adsorbent amount of 20 g/L, an initial concentration of 10 mg/L, and a contact time of 120 min. Under optimum conditions, 98.91% dye removal efficiency was obtained. Besides, the isotherm, kinetic, and thermodynamic were studied for the adsorption process. Accordingly, the removal of Safranin-O dye by the Leo-Ca-Alg adsorbent can be defined by the Freundlich model and described by the Elovich model and the second-order kinetic model at concentrations of 10 and 20–30 mg/L, respectively. The Safranin-O removal by Leo-Ca-Alg was feasible and naturally spontaneous. In reuse cycle studies, it was tried up to 10 reuses and decreased from 98.91 to 83.01% in the 10th use.
“Todo mundo tem corpo de biquíni”: problematizando a gordofobia e padrões de feminilidades a partir do filme Dumplin (2018)
Authors: De Jesus Souza Elaine , Paula da Rocha Eugerbia , Santos Claudiene
Published: June 2023

Neste estudo, analisamos discursos sobre feminismos e feminilidades juvenis no contexto escolar do Cariri cearense a partir da problematização de artefatos culturais. A pesquisa contou com 13 estudantes jovens mulheres de escolas públicas estaduais, por meio de uma entrevista coletiva, com a análise foucaultiana do discurso para examinar o material empírico. Os resultados obtidos evidenciaram que as feminilidades juvenis são marcadas por padrões normativos estereotipados, bullying, violências e preconceitos, como a gordofobia, bem como o não reconhecimento das múltiplas feminilidades. Assim, concluímos enfatizando a importância de incorporar o debate sobre os feminismos e as feminilidades nos currículos escolares e acadêmicos.
Resistências aos discursos hegemônicos nas HQs: o olhar das quadrinistas latino-americanas acerca dos gêneros e das sexualidades
Authors: Oliveira Barros Ana Paula
Published: June 2023

Nas sociedades ocidentais, tanto os corpos como as sexualidades das mulheres, foram durante muito tempo representados de modos idealizados e baseados nos valores de uma sociedade patriarcal, e isso se refletiu, também nas histórias em quadrinhos (HQs). Porém, a pesquisa desenvolve a hipótese de que estão acontecendo importantes reinvenções dos sentidos atribuídos aos corpos e às sexualidades associadas ao feminino no campo das HQs. Desse modo, o principal objetivo desta pesquisa consiste em investigar de que maneira, nas últimas décadas, algumas quadrinistas, principalmente, latino-americanas têm abordado os corpos e as sexualidades femininas em suas obras, adotando diferentes estratégias de resistência à colonialidade de gênero e aos discursos patriarcais, racistas e eurocêntricos em torno da ideia de feminilidade hegemônica.
Desmantelando sistemas de controle: o ato de criação queer como resistência no cinema brasileiro contemporâneo
Authors: Oliveira Silva Daniel
Published: June 2023

Pensar em um cinema queer é refletir sobre como o audiovisual, com suas estratégias estético-narrativas, pode contribuir para uma proposta antinormativa de gênero e sexualidade. A partir de uma revisão sistemática de literatura, centrada em pesquisadores/as do sul global que, numa perspectiva decolonial, têm deglutido e reconfigurado os estudos queer para seus contextos específicos, este artigo investiga a noção de que uma série de filmes contemporâneos tem concretizado esse propósito com a encenação de um ato de criação queer (Silva, 2021), tentando identificá-lo no cinema brasileiro atual. Para isso, a análise elabora um diálogo entre as provocações desses/as teóricos/as, com o intuito de tensionar em que medida pode-se enxergar o a produção nacional como um ato de criação ela mesma, capaz de fabular narrativas de gênero e sexualidade – e, com isso, melhor compreender a ideia de um “cinema queer” no Brasil.
Reasons for and time to seeking healthcare in cardiac clinics by women with a history of successfully treated breast cancer
Authors: Kushnareva E.A. , Astafurova O.E. , Zorina E.Yu. , Moiseeva O.M.
Published: June 2023

Background: Various methods of breast cancer treatment are potentially cardiotoxic: anthracycline chemotherapy, HER2-targeted therapy, and radiation therapy to the left side of the chest. In clinical practice, cardiologists deal with a wide range of complications caused by the mentioned methods.Objective: To analyze the reasons for and timing of seeking healthcare in cardiac clinics by women with a history of successfully treated breast cancer.Methods: Our single-center retrospective observational study included 125 women (mean age at the time of seeking healthcare was 68.1 ± 8.6 years).Results: Patients with a history of radiation therapy had higher peak velocity (P = .015) and peak gradient (P = .017) across the aortic valve. As part of their examination and treatment 71 patients underwent coronary angiography. Of them, 21 patients (29.6%) had coronary artery stenting, and 23 patients (32.4%) underwent coronary artery bypass grafting. Forty-two patients (33.6%) underwent heart valve replacement: aortic valve replacement in 92.9% of the cases (n = 39) and mitral valve replacement in 7.1% of the cases (n = 3). We found a strong negative correlation between the age at the time of radiation therapy and the time to onset of valvular heart disease (r = −0.748; P = .000004) and an average negative correlation between the age and the time to surgical treatment (r = −0.695; P = .00003).Conclusion: We studied the main reasons for seeking healthcare in cardiac clinics by women with a history of breast cancer, analyzed cardiac operations in terms of antitumor therapy types, and found a strong correlation between the age at the time of antitumor therapy and the time to onset of valvular heart disease, as well as the time to cardiac surgery.
Received 20 November 2022. Revised 21 May 2023. Accepted 31 May 2023.
Funding: The study was supported by Ministry of Science and Higher Education of Russian Federation (No. 075-15-2022-301).
Conflict of interest: The authors declare no conflict of interest.
Contribution of the authors: The authors contributed equally to this article.
Immediate outcomes of transcatheter aortic valve implantation in patients with horizontal aorta
Authors: Baranov A.A. , Krestyaninov O.V. , Badoian A.G. , Khelimskii D.A. , Manukian S.N. , Tsydenova A.Yu. , Makhmudov M.A.
Published: June 2023

Background: Transcatheter aortic valve implantation (TAVI) is an effective and safe procedure for severe aortic stenosis. Increased aortic root angulation is an important anatomical feature that may cause technical difficulties and negatively affect immediate and long-term outcomes.Objective: To evaluate immediate outcomes of TAVI in patients with increased aortic root angulation.Methods: Our retrospective single-center study included 412 patients with severe aortic stenosis who underwent TAVI using self-expanding bioprostheses from 2015 to 2022. Patients with aortic root angulation ≥ 49° were included in group 1 (n = 200), and those with aortic root angulation <  49° comprised group 2 (n = 212).Results: The mean age of the patients was 75.2 ± 7.2 years. In a subgroup with the first-generation CoreValve prosthesis and a ≥ 49° angle, we observed moderate aortic regurgitation significantly more often (7.4% vs 0.0%, P = .010) and technical success significantly less often (90.1% vs 98.9%, P = .010) compared with a similar subgroup with a <  49° angle. In subgroups with CoreValve Evolute R and ACURATE neo prostheses, there were no significant differences in terms of the mentioned parameters. Independent predictors of technical failure were the aortic root angle [OR for each degree increase: 0.44, 95% CI: 0.30-0.63, P < .001], no postdilation [OR: 5.0, 95% CI: 1.33-20.00, P = .074], indexed mass of the left ventricular myocardium [OR: 1.02, 95% CI: 1.01-1.03, P = .003], and higher implantation relative to the aortic annulus [OR for every 1 mm decrease in implantation depth: 0.44, 95% CI: 0.30-0.63, P < .001].Conclusion: Increased aortic angulation ≥ 49° negatively affected the technical success of TAVI only in patients with the first-generation CoreValve prostheses. Independent predictors of technical failure in TAVI were the aortic root angle, no postdilation, indexed mass of the left ventricular myocardium, and higher implantation relative to the aortic annulus.
Received 9 January 2023. Revised 10 May 2023. Accepted 30 May 2023.
Funding: The study did not have sponsorship.
Conflict of interest: The authors declare no conflict of interest.
Contribution of the authorsConception and study design: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. BadoianData collection and analysis: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. BadoianStatistical analysis: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. BadoianDrafting the article: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. Badoian, S.N. Manukian, A.Yu. Tsydenova, M.A. MakhmudovCritical revision of the article: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. Badoian, S.N. Manukian, A.Yu. Tsydenova, M.A. MakhmudovFinal approval of the version to be published: A.A. Baranov, O.V. Krestyaninov, D.A. Khelimskii, A.G. Badoian, S.N. Manukian, A.Yu. Tsydenova, M.A. Makhmudov
Regulação do trabalho via plataformas digitais na Alemanha e Portugal
Authors: Miranda Filho Vamberto Ferreira
Published: June 2023

This research constitutes a contribution to ongoing studies on work via digital platforms. The aim was to investigate how the initiatives of IG Metalland STRUP can contribute to the regulation of work via platforms. The theoretical framework used was the Power Resource Approach. This was a case study involving trade unions from two European countries, Germany, and Portugal. The sources of evidence werethree: interviews, documentation, and observation. The results obtained in the research pointed out weaknesses and strengths of these attempts at regulation.
Potencialidades, limites e desafios da prosopografia
Authors: Cardoso Cátia
Published: June 2023

This text aims to present and reflect on the strengths and limits of prosopography, having in consideration its advantages and challenges. The article therefore does not intend to discuss, as other authors have mentioned, whether prosopography is a technique, a method, a methodology or an exact science, but rather to understand how to evaluate its use. in this way and through a literature review, we understand that it is more appropriate to use it when we want to study more recent historical periods, however always being careful in what concerns validating the obtained information
Acidentes e lesões de trabalhadores agrícolas migrantes temporalidade, representação estatística, acontecimentos
Authors: Holmes Seth M.
Published: June 2023

This article considers ethnographic field research in order to analyze the violence and exploitation inherent to our transnational agro-food system and the ways in which temporality and statistics may aid in making visible and invisible certain experiences of migrant farmworker injury as well as individual and collective actions for wellbeing. Based in long-term, in-depth ethnographic research, this article utilizes theories of temporality and events in order to highlight social and health inequalities in agricultural labor and encourage agricultural, food and health scholars to consider critically the effects of our methods. Juxtaposing the injury and health care experiences of one Mexican migrant farmworker with statistics on the health and health care of migrant and seasonal farmworkers more generally, the article confronts both the normalization of migrant farmworker injury and the taken-for-granted helpfulness of quantitative and qualitative research alike. In addition, the argument acknowledges the everyday, individual practices and collective actions migrant farmworkers engage into demand and build wellbeing for themselves, their families and beyond.
A single arm clinical study to evaluate the efficacy of Ela Anjana and Paadaabhyanga in Prathama Patalagata Timira with special reference to Asthenopia
Authors: R. Chandana  , Naveen BS
Published: June 2023

Asthenopia is a broad term used to describe various symptoms under the umbrella of eye strain, which could be due to continuous reading, computer work or fine needle works. Asthenopia refers to mild eye ache, headache and tiredness of the eyes. It is a feature of extra ocular muscle imbalance and uncorrected mild refractive errors especially Astigmatism.[1] It’s been a common problem worldwide and is progressively increasing on the rising Covid-19. Stress and nutritional factors also contribute to improper vision. This symptom is mentioned in Ayurveda classics as Animitta Avyaktha Darshana in Prathama Patalagata Timira, a stage of Timira described under Drushtigata Rogas.[2] Anjana is one among the Kriyakalpa procedures administered in Netrarogas. According to Acharya Sushruta and Acharya Vagbhata, Anjana is of three types, namely Lekhana, Ropana and Prasadana. Paadaabhyanga is said to be Dristiprasadaka and stimulates the sensory peripheral nerves thus improving the sight. Ela Anjana[3] which is indicated in Timira Roga is explained by Acharya Charaka in Trimarmiya Chikita Adhyaya. Use of Ela Anjana also provides a nourishing effect to the eyes and improves visual activity. The study was carried out for a period of 30 days where in the intervention was for 7 days with two follow ups of seven days consecutively. Study yielded promising results in Asthenopic features, suggesting simple intervention in the form of Anjana and Paadaabhyanga can effectively help in managing Asthenopia.
An Ayurvedic approach in management of Asrigdara w.s.r. to Abnormal Uterine Bleeding
Authors: Apurva Joshi  , Rashmi Sharma
Published: June 2023

Asrigdara is a disease in which manifestation of excessive bleeding per vaginum takes place it is considered as one of the commonest leading gynaecological problems. Ayurveda texts have described a variety of treatment options in the management of Asrigdara including Shodhana and Shamana Chikitsa. Out of them, the efficacy of “Shodhana Chikitsa” is having prime importance as it expels out the vitiated Dosha from the body. Vishesh Chikitsa according to Dosha is being described. In modern medicine haemostatic, analgesic and hormonal therapies are advised for abnormal uterine bleeding, which includes hormonal therapy, ant prostaglandins & antifibrinolytic agents. These have not proven their definitive efficacy in spite of high costs; their side effects have led to hormonal imbalances hence it is need of time to have an integrated and comprehensive therapeutic intervention in Ayurveda to prevent recurrence& would overcome the modern medicine limitations. Many herbal & Herbo-mineral preparations, Shodhan & Shaman Chikitsa are mentioned in Ayurveda to cure Raktapradar and related symptoms which can be used as per Anubandha Dosha and Lakshana.
Importance of Srotas - An overview
Authors: Mayurkumar M. Parate  , Swati Vyas  , Ravindra Singh Baghel  , Arvind Kumar Yadav
Published: June 2023

Ayurveda has its own holistic approach to understand the Purush Sharir by different theories like Srotas, In Ayurvedic classics the term Srotas is used as all the macro and micro channels and pathways operating in the living organism. The concept of Srotas is unique contribution in the understanding of anatomy of human body. There is a description of Srotas by 13 Acharya Charak and 11 pairs of Srotas by Acharya Sushrut. Srotasas are the micro channels of the body which provide platform for activities of Tridosh, Dhatu, Oja, Agni etc. Acharyas also describe the anatomical origin of Srotas (Moola Sthana), its anatomy (shape), Dushti causes & Dusthi Lakshans (etiology & sign symptoms). The anatomical and physiological perspective of Srotas play vital role towards the normal health status of an individual since disturbed anatomical positioning and improper physiological functioning of Srotas can leads many health issues.
Scientific approach towards Dincharya - A Review
Authors: Achal R. Kapse  , Bhumika Dewangan  , Archana Solanki  , Roshani Sinha  , Yasmeen Parveen  , Pravin Kumar  , Bhupendra Marapi  , Aradhana Kande  , Kamna Singh
Published: June 2023

Ayurveda is perpetual science of life as it gives importance to quality of living and avoidance of diseases rather than treatment of diseases. As a result of stressful life, improper diet and sedentary lifestyle, the current world is facing lifestyle related disorders like obesity, diabetes etc. For maintaining health of healthy individual, Ayurveda has described many fundamental principles like Dincharya, Ritucharya, Sadvritta etc. As many articles published earlier provides information about processes to be followed in Dincharya, in this article the main emphasis is on the scientific importance of Dincharya.
Conceptual study on Agnikarma in Ayurveda
Authors: Maheshkumar Bharat Raut
Published: June 2023

Sushruta known as father of surgery has described various surgical procedures along with some parasurgical measures. ‘Agnikarma’ is one amongst these parasurgical procedures. Agnikarma has been given special place in surgery by Sushruta and it is believed that disease treated by Agnikarma never reoccurs. Agni is considered to be very high in therapy because the disease treated with it have no relapse and also those which are incurable by medicine, surgery and alkali application are cure by the fire therapy. Now a days it is used and it is termed as therapeutic burns or cauterization. This paper deals with details of various aspects of Agnikarma and its use in present context.