bluuebunny/crossref_metadata_2025 huggingface dataset:
Real-time laser speckle contrast imaging for intraoperative neurovascular blood flow assessment: animal experimental study
Authors: Konovalov Anton , Grebenev Fyodor , Stavtsev Dmitry , Kozlov Igor , Gadjiagaev Vadim , Piavchenko Gennadii , Telyshev Dmitry , Gerasimenko Alexander Yu. , Meglinski Igor , Zalogin Savely , Artemyev Anton , Golodnev Grigorii , Shumeiko Tatiana , Eliava Shalva
Published: January 2024

The use of various blood flow control methods in neurovascular interventions is crucial for reducing postoperative complications. Neurosurgeons worldwide use different methods, such as contact Dopplerography, intraoperative indocyanine videoangiography (ICG) video angiography, fluorescein angiography, flowmetry, intraoperative angiography, and direct angiography. However, there is no noninvasive method that can assess the presence of blood flow in the vessels of the brain without the introduction of fluorescent substances throughout the intervention. The real-time laser-speckle contrast imaging (LSCI) method was studied for its effectiveness in controlling blood flow in standard cerebrovascular surgery cases in rat common carotid arteries, such as proximal occlusion, trapping, reperfusion, anastomosis, and intraoperative vessel thrombosis. The real-time LSCI method is a promising method for use in neurosurgical practice. This approach allows timely diagnosis of intraoperative disturbance of blood flow in vessels in cases of clip occlusion or thrombosis. Additionally, LSCI allows us to reliably confirm the functioning of the anastomosis and reperfusion after removal of the clips and thrombolysis in real time. An unresolved limitation of the method is noise from movements, but this does not reduce the value of the method. Additional research is required to improve the quality of the data obtained.
Living mulch enhances soil enzyme activities, nitrogen pools and water retention in giant reed (Arundo donax L.) plantations
Authors: Elhawat Nevien , Kovács Andrea Balla , Antal Gabriella , Kurucz Erika , Domokos-Szabolcsy Éva , Fári Miklós Gábor , Alshaal Tarek
Published: January 2024

Giant reed (Arundo donax L.) is one of the most well-studied perennial biomass crops because of its high productivity and potential to store carbon. Yet, little information on controlling weeds in giant reed plantations and their influences on the soil ecosystem is available. In the present study, three different weed control methods, i.e., intercropping (living mulch) with sweet clover (Melilotus officinalis L.), herbicide (glyphosate), and hoeing, were investigated in a 2-year giant reed farm. The intercropping presented significantly higher values (on average) of all the tested soil properties than herbicide and hoeing, except for the catalase activity and pH. The dehydrogenase, phosphatase, and urease activities in the soil under intercropping were higher than the herbicide by 75%, 65%, and 80% (on average), respectively. Also, the soil under intercropping had higher soil organic matter (SOM) and soil respiration than the herbicide by 20% and 25%, respectively. Intercropping also increased the content of N pools, i.e., NO3−˗N, NH4+˗N, Org-N, and Total-N by 517%, 356%, 38%, and 137%, respectively, compared to herbicide. These findings illustrated that controlling weeds in biomass plantations through legume intercropping brings benefits not only to soil properties but also to biomass productivity.
PSGL-1 decorated with sialyl Lewisa/x promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement
Authors: O’Dwyer Michael , Kirkham-McCarthy Lucy , Cerreto Marina , Foà Robin , Natoni Alessandro
Published: January 2024

Dissemination of multiple myeloma into the bone marrow proceeds through sequential steps mediated by a variety of adhesion molecules and chemokines that eventually results in the extravasation of malignant plasma cells into this protective niche. Selectins are a class of C-type lectins that recognize carbohydrate structures exposed on blood borne cells and participate in the first step of the extravasation cascade, serving as brakes to slow down circulating cells enabling them to establish firm adhesion onto the endothelium. Myeloma cells enriched for the expression of selectin ligands present an aggressive disease in vivo that is refractory to bortezomib treatment and can be reverted by small molecules targeting E-selectin. In this study, we have defined the molecular determinants of the selectin ligands expressed on myeloma cells. We show that PSGL-1 is the main protein carrier of sialyl Lewisa/x-related structures in myeloma. PSGL-1 decorated with sialyl Lewisa/x is essential for P-selectin binding but dispensable for E-selectin binding. Moreover, sialylation is required for E-selectin engagement whereas high affinity binding to P-selectin occurs even in the absence of sialic acid. This study provides further knowledge on the biology of selectin ligands in myeloma, opening the way to their clinical application as diagnostic tools and therapeutic targets.
Compound heterozygous MSH3 germline variants and associated tumor somatic DNA mismatch repair dysfunction
Authors: Koi Minoru , Leach Brandie H. , McGee Sarah , Tseng-Rogenski Stephanie S. , Burke Carol A. , Carethers John M.
Published: January 2024

We describe here an individual from a fourth family with germline compound heterozygous MSH3 germline variants and its observed biological consequences. The patient was initially diagnosed with invasive moderately-differentiated adenocarcinoma of the colon at the age of 43. Germline multigene panel testing revealed a pathogenic variant MSH3 c.2436-1 G > A and a variant of (initial) uncertain significance MSH3 c.3265 A > T (p.Lys1089*). Germline genetic testing of family members confirm the variants are in trans with the c.2436-1 G > A variant of paternal and the c.3265 A > T variant of maternal origin. Tumor DNA exhibits low levels of microsatellite instability and elevated microsatellite alterations at selected tetranucleotide repeats (EMAST). Tissue immunohistochemical staining for MSH3 demonstrated variant MSH3 protein is present in the cytoplasm and cell membrane but not in the nucleus of normal and tumor epithelial cells. Furthermore, variant MSH3 is accompanied by loss of nuclear MSH6 and a reduced level of nuclear MSH2 in some tumor cells, suggesting that the variant MSH3 protein may inhibit binding of MSH6 to MSH2.
Isothermal amplification-based microfluidic devices for detecting foodborne pathogens: a review
Authors: Trinh Thi Ngoc Diep , Nam Nguyen Nhat
Published: January 2024

Different microfluidic platforms which integrated isothermal amplification methods including LAMP, RPA, and RAA were proposed to rapidly detect foodborne pathogens.
A density functional theory benchmark on antioxidant-related properties of polyphenols
Authors: Mendes Rodrigo A. , da Mata Victor A. S. , Brown Alex , de Souza Gabriel L. C.
Published: January 2024

In this work, we present a density functional theory benchmark on antioxidant-related properties for a series of six polyphenols that are well-known antioxidants: caffeic acid, cyanidin, ellagic acid, gallic acid, myricetin, and phloretin.
Excellent ratiometric two-photon fluorescent probes for hydrogen sulfide detection based on the fluorescence resonance energy transfer mechanism
Authors: Ma Xue-Xue , Geng Ming-Hui , Cheng Xia-Yu , Zhang Tong-Shu , Li Zong-Liang , Zhao Ke
Published: January 2024

Through regulating benzene-fused positions, fluorescence efficiency and TPA are enhanced significantly. Unique TPA spectra are revealed for the first time.
Influence of surface nanostructure-induced innermost ion structuring on capacitance of carbon/ionic liquid double layers
Authors: Tu Yi-Jung , Peng Sheng-Ting
Published: January 2024

Surface nanostructure-induced innermost ion structuring plays a key role in controlling cation–anion separation in ionic liquid double layers as well as enhancement of differential capacitance.
A hierarchical carbon foam-hosted Co2P nanoparticles monolithic electrode for ampere-level and super-durable electrocatalytic hydrogen production
Authors: Zhao Yaoyao , Zhang Zhengguo , Wang Fang , Min Shixiong
Published: January 2024

A hierarchical carbon foam-hosted Co2P nanoparticles monolithic electrode (Co2P@HCF) is developed and exhibits ultralow overpotentials and remarkable durability for ampere-level current density HER in both acidic and alkaline solutions.
Starch esterification using deep eutectic solvents as chaotropic agents and reaction promoters
Authors: Portillo-Perez Guillermo A. , Skov Kasper B. , Martinez Mario M.
Published: January 2024

Choline chloride (ChCl):urea and acetic anhydride represents a homogeneous, efficient and sustainable reaction system for starch esterification.
Stable and active methanol oxidation via anchored PtRu alloy nanoparticles on NiFe layered double hydroxides
Authors: Jin Linbo , Meng Qingcheng , Ma Mengze , Gao Xueqing , Chen Aibing , Sun Xiaoming , Zhou Daojin
Published: January 2024

Enhancing the catalytic efficiency of the methanol electro-oxidation reaction (MOR) holds paramount importance in expediting the commercialization of direct methanol fuel cells (DMFCs).
Embedding an esterase mimic inside polyesters to realize rapid and complete degradation without compromising their utility
Authors: Wu Yanfen , Tian Jing , Sun Minmin , Gao Lizeng , Xu Jun , Niu Zhiqiang
Published: January 2024

This work presents an innovative method to manage post-consumer biodegradable plastics by embedding a molecular mimic of esterase into poly(butylene terephthalate/adipate), which holds the potential to elevate composting efficiency and capacity.
Reduction-responsive and tumor-targeted polyprodrug nanocarriers for targeting therapy of hepatocellular carcinoma
Authors: Shi Wei , Xu Xiaoqing , Tian Jinyuan , Zhang Ziyi , Liu Zhanjun
Published: January 2024

DOX@HA-SS-PFA NPs, a targeted and reduction-responsive nano-delivery platform for polyprodrug, could effectively boost the therapeutic effect of the antitumor drug and improve the therapeutic efficiency.
Synthesis of 2-benzyl benzoxazoles and benzothiazoles via elemental sulfur promoted cyclization of styrenes with 2-nitrophenols and N,N-dialkyl-3-nitroanilines
Authors: Chau Truong K. , Ho Nguyen T. , Ho Tuan H. , Nguyen Anh T. , Nguyen Khoa D. , Phan Nam T. S. , Le Ha V. , Nguyen Tung T.
Published: January 2024

Annulation of 2-nitrophenols and N,N-dialkyl-3-nitroanilines with styrenes in the presence of elemental sulfur and the base DABCO successfully yielded 2-benzyl benzoxazoles and 2-benzyl benzothiazoles, respectively.
Anionic photochemical rearrangement of 3-hydroxypyran-4-ones bearing oxazol-2-one fragment
Authors: Komogortsev Andrey N. , Melekhina Valeriya G. , Lichitskii Boris V.
Published: January 2024

Blue LED irradiation (450 nm) of substituted 3-hydroxypyran-4-ones in the presence of DBU leads to the formation of isomeric 3-hydroxypyran-2-ones.
Stereoselective synthesis of thailandamide A methyl ester
Authors: Sharma Himangshu , Ganguly Swapnamoy , Sahana Moinul Haque , Goswami Rajib Kumar
Published: January 2024

A convergent route of total synthesis of structurally challenging polyene polyketide thailandamide A methyl ester has been achieved. Notably, a less explored Pd(i)-based Heck coupling has been introduced to couple two major segments quite efficiently.
Amino-modified 2-oxazoline copolymers for complexation with DNA
Authors: Oleszko-Torbus Natalia , Mendrek Barbara , Wałach Wojciech , Fus-Kujawa Agnieszka , Mitova Violeta , Koseva Neli , Kowalczuk Agnieszka
Published: January 2024

Novel amino-functionalized 2-oxazoline-based copolymers able to form complexes with DNA were obtained. Their efficiency of DNA condensation into polyplexes of scales appropriate for effective cellular internalization was studied.
Image enhancement with intensity transformation on embedding space
Authors: Kim Hanul , Jeon Yeji , Koh Yeong Jun
Published: January 2024

In recent times, an image enhancement approach, which learns the global transformation function using deep neural networks, has gained attention. However, many existing methods based on this approach have a limitation: their transformation functions are too simple to imitate complex colour transformations between low‐quality images and manually retouched high‐quality images. In order to address this limitation, a simple yet effective approach for image enhancement is proposed. The proposed algorithm based on the channel‐wise intensity transformation is designed. However, this transformation is applied to the learnt embedding space instead of specific colour spaces and then return enhanced features to colours. To this end, the authors define the continuous intensity transformation (CIT) to describe the mapping between input and output intensities on the embedding space. Then, the enhancement network is developed, which produces multi‐scale feature maps from input images, derives the set of transformation functions, and performs the CIT to obtain enhanced images. Extensive experiments on the MIT‐Adobe 5K dataset demonstrate that the authors’ approach improves the performance of conventional intensity transforms on colour space metrics. Specifically, the authors achieved a 3.8% improvement in peak signal‐to‐noise ratio, a 1.8% improvement in structual similarity index measure, and a 27.5% improvement in learned perceptual image patch similarity. Also, the authors’ algorithm outperforms state‐of‐the‐art alternatives on three image enhancement datasets: MIT‐Adobe 5K, Low‐Light, and Google HDR+.
Spectrum utilization improvement for multi‐channel EH‐CRN with spectrum sensing
Authors: Zheng Kechen , Wang Jiahong , Chen Anping , Sun Wendi , Liu Xiaoying , Liu Jia
Published: January 2024

Due to the ever‐growing applications and services of the Internet of Things (IoT), designing energy‐efficient and spectral‐efficient transmission schemes to support IoT devices for the 6G space–air–ground integrated networks becomes much more challenging. Fortunately, energy harvesting (EH) and cognitive radio (CR) technologies have been proposed to alleviate these challenges. Inspired by this fact, this paper studies the issue of spectrum reuse in terms of spectrum utilization efficiency (SUE) in the energy harvesting cognitive radio network (EH‐CRN), where multiple primary transceiver pairs, one multi‐antenna secondary transmitter (ST), and one secondary base station (SBS) coexist. To characterize the impact of small‐scale fading and improve the SUE of the EH‐CRN with perfect spectrum sensing (SS), an adaptive scheme concerning SS, channel selection, EH, and data transmission (SCED) scheme are proposed, where the ST selects the channels for SS based on the residual energy, and adjusts the duration of EH and data transmission with respect to the sensing results. Then the Markov decision process problem of SUE is formulated, which is challenging due to the infinite system space and action space. To tackle the Markov decision process problem, the system space and action space are discreted, and divide the ST into the energy‐limited case and energy‐sufficient case according to specific energy condition. Moreover, theoretical results are extended to the EH‐CRN with imperfect SS. Numerical results show that the SUE under the SCED scheme in perfect SS and imperfect SS scenarios is better than that under other schemes.
Adversarial catoptric light: An effective, stealthy and robust physical‐world attack to DNNs
Authors: Hu Chengyin , Shi Weiwen , Tian Ling , Li Wen
Published: January 2024

Recent studies have demonstrated that finely tuned deep neural networks (DNNs) are susceptible to adversarial attacks. Conventional physical attacks employ stickers as perturbations, achieving robust adversarial effects but compromising stealthiness. Recent innovations utilise light beams, such as lasers and projectors, for perturbation generation, allowing for stealthy physical attacks at the expense of robustness. In pursuit of implementing both stealthy and robust physical attacks, the authors present an adversarial catoptric light (AdvCL). This method leverages the natural phenomenon of catoptric light to generate perturbations that are both natural and stealthy. AdvCL first formalises the physical parameters of catoptric light and then optimises these parameters using a genetic algorithm to derive the most adversarial perturbation. Finally, the perturbations are deployed in the physical scene to execute stealthy and robust attacks. The proposed method is evaluated across three dimensions: effectiveness, stealthiness, and robustness. Quantitative results obtained in simulated environments demonstrate the efficacy of the proposed method, achieving an attack success rate of 83.5%, surpassing the baseline. The authors utilise common catoptric light as a perturbation to enhance the method's stealthiness, rendering physical samples more natural in appearance. Robustness is affirmed by successfully attacking advanced DNNs with a success rate exceeding 80% in all cases. Additionally, the authors discuss defence strategies against AdvCL and introduce some light‐based physical attacks.
Design and evaluation of architectural framework for a secured local energy market model based on distributed ledger technologies
Authors: Okwuibe Godwin C. , Brenner Thomas , Yahya Muhammad , Tzscheutschler Peter , Hamacher Thomas
Published: January 2024

Blockchain‐based local energy markets have been proposed in recent years to provide a market platform for local prosumers and consumers to exchange their energy in a secured, transparent and tamper‐proof manner. However, there are still some challenges regarding the scalability of blockchain to handle high computational models/algorithms/contracts as this may result in the extension of the block size of the blockchain network and very high gas costs. Also, there is still the problem of transparency as regards General Data Protection Regulation because the full visibility of data in the blockchain may collide with privacy in some settings. A framework is presented that combines the on‐chain features of blockchain with trusted execution environments to develop a transparent, tamper‐resistant, low operation cost, scalable and resilient hybrid model architecture for local electricity trading. The model architecture was simulated in German community case scenarios for a varying number of prosumers and consumers to show its applicability. The simulation results show that the model was able to solve the scalability problem of blockchain for the local energy market application as the market model is run in a trusted environment where the integrity of the model can be verified by the participants.
Model predictive current control based on hybrid control set for permanent magnet synchronous motor drives
Authors: Zhu Jincong , Duan Qianwen , Bao Qiliang , Mao Yao
Published: January 2024

Model predictive current control (MPCC) has been widely recognized as a high‐performance scheme for permanent magnet synchronous motor drives because of its simple control structure. This article proposes a novel multivector MPCC (MMPCC) method based on a hybrid control set, which includes both original basic voltage vectors (VVs) and synthesized VVs. The two active VVs and one null VV are considered as an initial control set, and the exact combination of them depends on their corresponding durations, which are calculated by stator current slopes in frame with the use of the prediction formula. Contrary to the traditional cost function, an alternative hybrid control set can achieve superior voltage precision. This is due to the involved cost function that minimizes the maximum of prediction current errors, which typically occur at non‐integer sample instants during the control period. The performance of the proposed MMPCC method has been experimented to confirm its effectiveness, compared with the conventional MPCC (CMPCC) and duty‐cycle MPCC (DMPCC). The results indicated an anticipated enhancement in both dynamic and steady‐state performance at a low rotor speed, alongside a significant robustness against parameter mismatch.
La parentalité entre l’inter- et le trans-générationnel : une co-construction où les ancêtres ne sont pas oubliés
Authors: Baruch Florence , Pisanté Jean
Published: January 2024

Cet article décrit les principaux éléments du suivi des parents d’un garçon de 12 ans conduit en consultation pour crises de rage et présentant des antécédents de comportements incendiaires. Ce suivi s’est déroulé au Centre Lamerchav, une clinique de référence psychodynamique desservant la communauté ultra-orthodoxe de Jérusalem. Le récit de la dernière séance de cette thérapie est particulièrement détaillé.

L’analyse de ces éléments fait appel aux principaux concepts du modèle de Thérapie Familiale Psychanalytique développé en France, et permet notamment d’interroger les notions de mythopoïèse familiale, de transmission transgénérationnelle, d’auto-parentalité et de fondements psychiques du couple.
Coupure corporelle et coupure psychique ou Penser pour mieux panser
Authors: Smotriez Karine
Published: January 2024

Travailler comme psychologue dans un service de neurochirurgie pédiatrique nécessite toute une réflexion autour de la non-demande du petit patient et de ses parents ainsi qu’une adaptation au plus près de la pathologie de l’enfant qui va subir une intervention chirurgicale. Comme exemple de ma pratique, je présente mon travail d’accompagnement psychologique auprès des bébés souffrant de craniosynostoses ainsi qu’auprès de leurs parents et de leur fratrie afin de prévenir au mieux les effets secondaires dans la relation du bébé à l’ensemble de son environnement familial.
Approximate proper efficiencies in nonsmooth semi-infinite multiobjective optimization problems
Authors: Pham Thanh-Hung
Published: January 2024

This article is devoted to studying a nonsmooth semi-infinite multiobjective optimization problem (SIMP) in terms of the Mordukhovich/limiting subdifferentials. We first establish necessary and sufficient conditions for an ε-quasi positively properly efficient solution of a problem (SIMP). We also investigate Mond–Weir type dual problems under assumptions of ε-quasi pseudo-generalized convexity. Next, we provide an application to a nonsmooth fractional semi-infinite multiobjective optimization problem. Finally, some examples are given to illustrate the obtained results. The obtained results improve or include some recent known ones.
Long-Covid: Zur Genealogie einer neuen Krankheit und Chance einer
kultursoziologischen (Forschungs-)Perspektive
Authors: Weihrauch Stephan , Winkler Torsten
Published: January 2024

Der Beitrag beschäftigt sich mit der Frage, wie Long-Covid zu einer
Krankheit geworden ist. Dabei interessieren die Bahnungen und Prägungen,
wie sich ein Problem als solches bewahrheitet und materialisiert, bzw. wie die
Gesellschaft zur Erkenntnis ihrer Probleme gelangt. Die mittlerweile
weitreichende Institutionalisierung von Long-Covid als Krankheit täuscht
dabei über bestehende Deutungskämpfe bei und um Long-Covid
hinweg. Wie hier Be-Deutung hergestellt und wirksam wird, wäre
Ausgangspunkt einer praxeologischen Kulturanalyse, wie sie hier vorgeschlagen
wird.
Glycosaminoglycans: Participants in Microvascular Coagulation of Sepsis
Authors: Li Nanxi , Hao Ruolin , Ren Peng , Wang Jingya , Dong Jiahui , Ye Tong , Zhao Danyang , Qiao Xuan , Meng Zhiyun , Gan Hui , Liu Shuchen , Sun Yunbo , Dou Guifang , Gu Ruolan
Published: January 2024

Sepsis represents a syndromic response to infection and frequently acts as a common pathway leading to fatality in the context of various infectious diseases globally. The pathology of severe sepsis is marked by an excess of inflammation and activated coagulation. A substantial contributor to mortality in sepsis patients is widespread microvascular thrombosis-induced organ dysfunction. Multiple lines of evidence support the notion that sepsis induces endothelial damage, leading to the release of glycosaminoglycans, potentially causing microvascular dysfunction. This review aims to initially elucidate the relationship among endothelial damage, excessive inflammation, and thrombosis in sepsis. Following this, we present a summary of the involvement of glycosaminoglycans in coagulation, elucidating interactions among glycosaminoglycans, platelets, and inflammatory cells. In this section, we also introduce a reasoned generalization of potential signal pathways wherein glycosaminoglycans play a role in clotting. Finally, we discuss current methods for detecting microvascular conditions in sepsis patients from the perspective of glycosaminoglycans. In conclusion, it is imperative to pay closer attention to the role of glycosaminoglycans in the mechanism of microvascular thrombosis in sepsis. Dynamically assessing glycosaminoglycan levels in patients may aid in predicting microvascular conditions, enabling the monitoring of disease progression, adjustment of clinical treatment schemes, and mitigation of both acute and long-term adverse outcomes associated with sepsis.
The CDH Study Group: Past, Present, and Future
Authors: Holden Kylie I. , Ebanks Ashley H. , Lally Kevin P. , Harting Matthew T.
Published: January 2024

The Congenital Diaphragmatic Hernia Study Group (CDHSG) is an international consortium of medical centers actively collecting and voluntarily contributing data pertaining to live born congenital diaphragmatic hernia (CDH) patients born and/or managed at their institutions. These data are aggregated to construct a comprehensive registry that participating centers can access to address specific clinical inquiries and track patient outcomes. Since its establishment in 1995, 147 centers have taken part in this initiative, including 53 centers from 17 countries outside the United States, with 95 current active centers across the globe. The registry has amassed data on over 14,000 children, resulting in the creation of over 75 manuscripts based on registry data to date. International, multicenter consortia enable health care professionals managing uncommon, complex, and diverse diseases to formulate evidence-based hypotheses and draw meaningful and generalizable conclusions for clinical inquiries. This review will explore the formation and structure of the CDHSG and its registry, outlining their functions, center participation, and the evolution of data collection. Additionally, we will provide an overview of the evidence generated by the CDHSG, with a particular emphasis on contributions post-2014, and look ahead to the future directions the study group will take in addressing CDH.
Pyrocarbon Lunate Arthroplasty: An Option for the Young Patient with Advanced Kienbock Disease
Authors: Dwivedi Shashank S. , Chung Kevin C.
Published: January 2024

Kienbock disease, or avascular necrosis of the lunate, is an uncommon cause of a painful and stiff wrist. Management options range from conservative treatment in the form of immobilization and corticosteroid injections to a wide variety of surgical treatments that depend on the structural integrity of the lunate, intercarpal relationships, and the condition of the articular cartilage of the wrist. A particularly difficult problem lies in the management of young patient in whom vascularized bone grafting of the lunate has failed but in whom arthritis has not yet developed. Pyrocarbon lunate implant arthroplasty is a newer treatment option for such a patient, and allows the preservation of the remainder of the proximal carpal row while directly addressing the degenerative lunate. This article describes the evidence and surgical technique for lunate implant arthroplasty and presents an illustrative case example.
Retraction Note: The Effects of Quran Recitation on Sedation and Pain in Children
Authors: Çaksen Hüseyin
Published: January 2024

Retraction

An investigation by the publisher found a number of articles, including this one, published in Journal of Pediatric Intensive Care on January 13, 2023 (DOI: 10.1055/s-0042-1760632), with a number of concerns, including but not limited to undeclared conflicts of interest and manipulated peer review procedures. As a result, the publisher has retracted and removed this article.
Retraction Note: A Spiritual Prescription for Patients with Stroke
Authors: Çaksen Hüseyin
Published: January 2024

Retraction

An investigation by the publisher found a number of articles, including this one, published in Journal of Pediatric Neurology on September 15, 2022 (DOI: 10.1055/s-0042-1756448), with a number of concerns, including but not limited to undeclared conflicts of interest and manipulated peer review procedures. As a result, the publisher has retracted and removed this article.
Retraction Note: The Prophet Isa's (Alayhi As-Salam) Miracle of “Bringing the Dead into Life”: A Message to Intensivists
Authors: Çaksen Hüseyin
Published: January 2024

Retraction

An investigation by the publisher found a number of articles, including this one, published in Journal of Pediatric Intensive Care in Volume 12, Number 01, 1-2, in March 2023 (DOI: 10.1055/s-0042-1758746), with a number of concerns, including but not limited to undeclared conflicts of interest and manipulated peer review procedures. As a result, the publisher has retracted and removed this article.
Retraction Note: The Miracle of Ibrahim's (Alayhi As-Salam) “The Fire that Does Not Burn”: Lessons to Today's Health Professionals
Authors: Çaksen Hüseyin
Published: January 2024

Retraction

An investigation by the publisher found a number of articles, including this one, published in Journal of Pediatric Neurology on February 06, 2023 (DOI: 10.1055/s-0043-1761484), with a number of concerns, including but not limited to undeclared conflicts of interest and manipulated peer review procedures. As a result, the publisher has retracted and removed this article.
Retraction Note: The Sacrifice of Ismail by His Father Ibrahim (Alayhi As-Salam): An Example of Surrender for Today's Children and Parents
Authors: Çaksen Hüseyin
Published: January 2024

Retraction

An investigation by the publisher found a number of articles, including this one, published in Journal of Pediatric Neurology on March 15, 2023 (DOI: 10.1055/s-0043-1762922), with a number of concerns, including but not limited to undeclared conflicts of interest and manipulated peer review procedures. As a result, the publisher has retracted and removed this article.
Organizational responses to scandals: how effective is the European Commission?
Authors: Cini Michelle
Published: January 2024

How public organizations respond to scandals is important as it affects their reputation and legitimacy. Yet very little research has been conducted on this topic. Drawing on insights from the literature on corporate reputation management, this article questions how effectively the European Commission has responded to recent scandals. It does this by creating an original analytical framework composed of five indicators: speed of response; openness of response; application of relevant rules; tone of response; and engagement with reform. These indicators are then used to evaluate two cases of Commission scandal: the first, a cash-for-influence case involving a Commissioner from a small Member State; and the second, concerning a former Commission President. While no clear pattern emerges across the two cases, the article provides evidence of a mix of good practice and room for improvement in the Commission’s handling of scandals. The article also argues that even in the most bureaucratic of public organizations the management of scandals involves not only rule-following, but also subjective judgements by organizational leaders.
Emerging optoelectronic artificial synapses and memristors based on low-dimensional nanomaterials
Authors: Xie Pengshan , Li Dengji , Yip SenPo , Ho Johnny C.
Published: January 2024

The Von Neumann architecture has been the foundation of modern computing systems. Still, its limitations in processing large amounts of data and parallel processing have become more apparent as computing requirements increase. Neuromorphic computing, inspired by the architecture of the human brain, has emerged as a promising solution for developing next-generation computing and memory devices with unprecedented computational power and significantly lower energy consumption. In particular, the development of optoelectronic artificial synaptic devices has made significant progress toward emulating the functionality of biological synapses in the brain. Among them, the potential to mimic the function of the biological eye also paves the way for advancements in robot vision and artificial intelligence. This review focuses on the emerging field of optoelectronic artificial synapses and memristors based on low-dimensional nanomaterials. The unique photoelectric properties of these materials make them ideal for use in neuromorphic and optoelectronic storage devices, with advantages including high carrier mobility, size-tunable optical properties, and low resistor–capacitor circuit delay. The working mechanisms, device structure designs, and applications of these devices are also summarized to achieve truly sense-storage-computer integrated optoelectronic artificial synapses.
Microfluidic organ chip of fluid–solid dynamic curved interface
Authors: Su Haoran , Ma Tianxiang , Liu Xiao , Wang Li , Shu Fangjun , Liang Zhuqing , Zhang Dongrui , Zhang Xing , Li Kexin , Wang Min , Xin Chen , Zhang Yu , Zhang Jing , Du Yao , Fan Yubo
Published: January 2024

Dynamic curved interfaces are fundamental and ubiquitous structures in biological systems. However, replicating the structure and function associated with these interfaces for mechanobiology and drug screening is challenging. Here, we develop a dynamic curvature-enabled microfluidic organ chip of two fluid–solid dynamic curved interfaces. One interface effectively integrates adjustable biomechanics, and the other controls drug release with open microfluidics. The fluid–solid interface sensed by the cells can modulate the residual stress, stiffness, strain of the solid phase, and the flow shear stress of the fluid phase. Using the chip, we investigate the mechanotransductive responses of endothelial and epithelial cells, including Piezo1, Ca2+, and YAP, and reveal that the response of the endothelium to combined dynamic cyclic strain and flow shear stress is different from separate stimulation and also disparate from the epithelium. Furthermore, direct and high-efficiency drug release to cells is realized by constructing the other fluid–solid interface on the back side of cells, where drugs are encapsulated within cross-linked alginate hydrogel in the open microfluidic channel. Then, we replicate object-specific and location-specific biomechanical environments within carotid bifurcation and prove the effectiveness of drug delivery. Our design exemplifies dynamic curved biological interfaces with controlled mechanical environments and holds potential for patient-specific medicine.
Experimental validation of group delay in a multi-window electromagnetically induced transparency metasurface
Authors: Chen Jing , Breslavets Oleksiy A. , Savin Yuri N. , Kupriianov Anton S. , Eremenko Zoya E. , Tuz Vladimir R.
Published: January 2024

Metasurface analogs of electromagnetically induced transparency (EIT) are attracting sustaining attention due to their ability to maintain transparency windows accompanied by extreme dispersion of propagating waves, which are important for slow light devices and highly sensitive optical sensors. In this paper, we study theoretically, numerically, and experimentally the conditions for the existence of multi-band transparency windows in the metasurface supported by the interaction of dipole modes in an asymmetric unit cell. The unit cell is composed of a single bright resonator and several dark resonators made in the form of rectangular metal patches. The manifestation of EIT is studied for different metasurface configurations by varying the number and positions of resonators used within the unit cell. To validate the slow-down effect caused by EIT, a prototype of the metasurface is fabricated and tested, providing a measurement of the group delay and bandwidth-delay product features. The obtained results clearly confirm the presence of four EIT-like transparency windows in the metasurface transmission spectra originating from the coupling between either quasi-TE or quasi-TM modes of the resonators.
Study of electric-field induced ionic migration on all-inorganic perovskite CsPbBr3 single crystal nuclear radiation detector
Authors: Zhang Mingzhi , Xia Guotu , Huang Chentao , Liu Juan , Deng Wenjuan , Tian Fang , Zou Jijun , Tang Bin
Published: January 2024

As one of the promising room temperature nuclear radiation detection materials, the all-inorganic perovskite CsPbBr3 single crystal has been receiving much attention in recent years. Even though the performance of the CsPbBr3 detector is improving continuously, the disadvantages of detection instability have not been solved fundamentally, and this instability is mainly caused by ionic migration in the CsPbBr3 single crystal itself. In this paper, a reasonable ionic migration model is proposed based on an in-depth study of the current hysteresis phenomenon and ionic migration mechanism in the Ti/CsPbBr3/Ti detector. The model shows that the ions migrate to the anode or cathode under an external electric field, and the accumulated ions subsequently form an inverted internal electric field inside the crystal and carrier transport barriers at the metal–semiconductor interface simultaneously. The photoelectric characteristic and ionic migration activation energy (Eaion) fitting results also prove the rationality of the ionic migration model. Furthermore, the ionic migration model can also be used to explain the left-shift of the energy response peak and the decrease in the normalized charge collection efficiency in the Ti/CsPbBr3/Ti detector. This paper systematically investigates the intrinsic origin of migrated ions and the influence of ionic migration on detection stability, which will provide a potential solution to improve detection stability by suppressing ionic migration in the near future.
Performance improvement of a fractional quantum Stirling heat engine
Authors: Xia Shihao , Lv Minglong , Pan Yuzhuo , Chen Jincan , Su Shanhe
Published: January 2024

To investigate the impact of fractional parameters on the thermodynamic behaviors of quantum systems, we incorporate fractional quantum mechanics into the cycle of a quantum Stirling heat engine and examine the influence of fractional parameters on regeneration and efficiency. We propose a novel approach to control the thermodynamic cycle that leverages the fractional parameter structure and evaluates its effectiveness. Our findings reveal that by tuning the fractional parameter, the region of the cycle with the perfect regeneration and the Carnot efficiency can be expanded.
Nutritional composition of plants and preliminary assessment of nutrition in free-ranging bare-nosed wombats (Vombatus ursinus)
Authors: Casey Fiona F. , Vallin Blaire T. , Wolfenden Jack , Old Julie M. , Stannard Hayley J.
Published: January 2024

Nutrition is essential for not only survival but also successful growth and reproduction. Dietary demands are increased in a diseased state due to the increased energy and nutritional requirements associated with immune response, inflammation and convalescence. The herbivorous bare-nosed wombat (Vombatus ursinus) is notably susceptible to sarcoptic mange, a disease caused by the mite, Sarcoptes scabiei, which causes debilitating pruritic skin disease and leads to secondary bacterial infections and increased wombat morbidity and mortality, as well as regionally variable population declines. It is unknown why wombats are so susceptible to sarcoptic mange and if nutrition may play a role in disease expression, particularly relating to seasonality. The objective of this study was to quantify the differences in the nutritive value, over four seasons, of plants (mostly grasses and sedges) that are available as food items for bare-nosed wombats. We collected plants over four seasons from five wombat habitats that were known to have wombats affected by sarcoptic mange. We found seasonal and site differences for macro and micronutrients in the plants analysed. Monitoring the diet quality of wombats in the wild is useful for managing their populations and understanding population dynamics in relation to food resource quality.
Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features
Authors: Juraska Michal , Bai Hongjun , deCamp Allan C. , Magaret Craig A. , Li Li , Gillespie Kevin , Carpp Lindsay N. , Giorgi Elena E. , Ludwig James , Molitor Cindy , Hudson Aaron , Williamson Brian D. , Espy Nicole , Simpkins Brian , Rudnicki Erika , Shao Danica , Rossenkhan Raabya , Edlefsen Paul T. , Westfall Dylan H. , Deng Wenjie , Chen Lennie , Zhao Hong , Bhattacharya Tanmoy , Pankow Alec , Murrell Ben , Yssel Anna , Matten David , York Talita , Beaume Nicolas , Gwashu-Nyangiwe Asanda , Ndabambi Nonkululeko , Thebus Ruwayhida , Karuna Shelly T. , Morris Lynn , Montefiori David C. , Hural John A. , Cohen Myron S. , Corey Lawrence , Rolland Morgane , Gilbert Peter B. , Williamson Carolyn , Mullins James I.
Published: January 2024

In the Antibody Mediated Prevention (AMP) trials (HVTN 704/HPTN 085 and HVTN 703/HPTN 081), prevention efficacy (PE) of the monoclonal broadly neutralizing antibody (bnAb) VRC01 (vs. placebo) against HIV-1 acquisition diagnosis varied according to the HIV-1 Envelope (Env) neutralization sensitivity to VRC01, as measured by 80% inhibitory concentration (IC80). Here, we performed a genotypic sieve analysis, a complementary approach to gaining insight into correlates of protection that assesses how PE varies with HIV-1 sequence features. We analyzed HIV-1 Env amino acid (AA) sequences from the earliest available HIV-1 RNA-positive plasma samples from AMP participants diagnosed with HIV-1 and identified Env sequence features that associated with PE. The strongest Env AA sequence correlate in both trials was VRC01 epitope distance that quantifies the divergence of the VRC01 epitope in an acquired HIV-1 isolate from the VRC01 epitope of reference HIV-1 strains that were most sensitive to VRC01-mediated neutralization. In HVTN 704/HPTN 085, the Env sequence-based predicted probability that VRC01 IC80 against the acquired isolate exceeded 1 µg/mL also significantly associated with PE. In HVTN 703/HPTN 081, a physicochemical-weighted Hamming distance across 50 VRC01 binding-associated Env AA positions of the acquired isolate from the most VRC01-sensitive HIV-1 strain significantly associated with PE. These results suggest that incorporating mutation scoring by BLOSUM62 and weighting by the strength of interactions at AA positions in the epitope:VRC01 interface can optimize performance of an Env sequence-based biomarker of VRC01 prevention efficacy. Future work could determine whether these results extend to other bnAbs and bnAb combinations.
HIV-1 capsid shape, orientation, and entropic elasticity regulate translocation into the nuclear pore complex
Authors: Hudait Arpa , Voth Gregory A.
Published: January 2024

Nuclear import and uncoating of the viral capsid are critical steps in the HIV-1 life cycle that serve to transport and release genomic material into the nucleus. Viral core import involves translocating the HIV-1 capsid at the nuclear pore complex (NPC). Notably, the central channel of the NPC appears to often accommodate and allow passage of intact HIV-1 capsid, though mechanistic details of the process remain to be fully understood. Here, we investigate the molecular interactions that operate in concert between the HIV-1 capsid and the NPC that regulate capsid translocation through the central channel. To this end, we develop a “bottom-up” coarse-grained (CG) model of the human NPC from recently released cryo-electron tomography structure and then construct composite membrane-embedded CG NPC models. We find that successful translocation from the cytoplasmic side to the NPC central channel is contingent on the compatibility of the capsid morphology and channel dimension and the proper orientation of the capsid approach to the channel from the cytoplasmic side. The translocation dynamics is driven by maximizing the contacts between phenylalanine-glycine nucleoporins at the central channel and the capsid. For the docked intact capsids, structural analysis reveals correlated striated patterns of lattice disorder likely related to the intrinsic capsid elasticity. Uncondensed genomic material inside the docked capsid augments the overall lattice disorder of the capsid. Our results suggest that the intrinsic “elasticity” can also aid the capsid to adapt to the stress and remain structurally intact during translocation.
Haunting Memory of Forgotten History: A Case Study of WWII “Comfort Stations” in the Philippines as a Tourism Resource Featured in Selected Filipino Films
Authors: Ani Aileen C.
Published: January 2024

The focus of this case study is the World War II “comfort stations” in the Philippines where the war victims during the Japanese occupation were held. For this case study, the scope is centralized on two main sites in the Philippines. Characters, settings, and the narratives of “comfort women” and “comfort gays” were analyzed from the two full-length Filipino films entitled
“Bahay na Pula”
and
“Markova: Comfort Gay”.
Within this context, the study assesses the potential of the featured “comfort stations” and other war-related sites in the films as a tourism resource that will educate tourists about war.

The concepts of
remembering
and
forgetting
are essential when understanding critical areas of history. Analyzing what specific events, persons, or memories people choose to retain or erase, reveals different factors and motivations that push them to do so. This case study argues that it is necessary to remember important historical sites in the Philippines, particularly the markers that have been commonly taken for granted and are slowly deteriorating. It uncovers forgotten sites, restores the memory, and transforms the historical significance of the “comfort stations” featured in Filipino films by analyzing the story being told, the kind of place being depicted, and the relevance of preserving them.

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