bluuebunny/crossref_metadata_2025 huggingface dataset:
Social microfranchise Serving the community: JIBU model is a "solution"
Authors: Stefanović Suzana , Stanković Milica
Published: October 2023

Social entrepreneurship is becoming increasingly important for the franchise business model. Social franchising is a useful strategy for growth and sustainability of social enterprises based on practices of corporate social responsibility (CSR). The paper starts from the basic assumption that global social goals can be achieved by using social microfranchise as a modern form of franchise business. Social microfranchises combine benefits and social goals of a social franchise and a microfranchise, while providing the necessary products and services to the poor and creating business opportunities for the poorest in the community. The aim of this paper is to point out the importance of social franchising and microfranchising as new forms of franchising that contribute to the wider community, focusing on the business example of Jibu social microfranchise operating in Africa and its global social impact. There are two key challenges facing developing countries in Africa: access to safe drinking water and high unemployment. Our research has shown that Jibu helps address both challenges by training local entrepreneurs to create a network of franchise units that provide permanent access to drinking water, which can have positive implications for solving other social problems of local communities in many underdeveloped and developing countries.
Global pandemic and digital marketing: Trends and perspectives
Authors: Lazić Milena , Domazet Ivana , Vukmirović Valentina
Published: October 2023

The Covid-19 pandemic has caused issues and significant challenges in all spheres of business activities. Digital marketing is no exception, which, although based on the application of information technologies and thereby its functioning was not vitally jeopardized, has undergone significant transformations. Accordingly, the aim of this paper is to identify keyt rendsin digital marketing that have arisen as a consequence of the global pandemic outburst. The paper analyzes the economic aspect, i.e. the impact of the pandemic on the growth of digital marketing observed through the total spending on digital advertising at the level of 28 European countries. Moreover, the aspect of adapting marketing communication to the new phenomena in society, such as living and working at home and rising isolation due to social distancing measures, was also observed. The results of the research contribute to the growing body of literature in the field of digital marketing by providing a systematic overview of the changes that have occurred, as well as development trends that are anticipated for the future period.
Nhà nước pháp quyền xã hội chủ nghĩa với pháp luật, pháp chế, pháp quyền trong quản trị xã hội
Authors: Hoàng Hùng Hải
Published: October 2023

Nhà nước pháp quyền xã hội chủ nghĩa thực hiện quản trị xã hội có nội dung vô cùng phong phú, đa dạng, trong đó các yếu tố pháp luật, pháp chế, pháp quyền đóng vai trò then chốt. Các yếu tố này đan xen nhau, có quan hệ mật thiết với nhau.
Về phân cấp, phân quyền trong lĩnh vực đất đai theo địa bàn đô thị và nông thôn
Authors: Trần Thị Diệu Oanh
Published: October 2023

Cơ chế phân định thẩm quyền được thực hiện một cấp địa phương có quyền quyết định về đất đai là phù hợp với đặc điểm đất đai là tài nguyên thiên nhiên cần được quản lý thống nhất và liên tục. Đây cũng là giải pháp tránh tạo ra những kẽ hở trong thực hiện thẩm quyền, đồng thời, kiểm soát tốt việc bảo đảm công khai, minh bạch, gắn với hệ thống kiểm tra, giám sát hiệu quả, giảm nguy cơ tham nhũng trong thực hiện thẩm quyền quản lý nhà nước về đất đai.
Những vấn đề đặt ra đối với tổ chức và hoạt động của chính quyền thị xã, thành phố thuộc tỉnh
Authors: Đào Mạnh Hoàn
Published: October 2023

Xây dựng nền quản trị quốc gia hiện đại, hiệu quả là yêu cầu, đòi hỏi tất yếu khách quan đốivới mỗi quốc gia trong quá trình phát triển. Ở Việt Nam, đây cũng là một nội dung quantrọng, có tính cấp thiết đặt ra trong quá trình đổi mới tổ chức và hoạt động của bộ máy nhànước nói chung, chính quyền thị xã, thành phố thuộc tỉnh nói riêng. Bên cạnh những kếtquả về đổi mới tổ chức, hoạt động của chính quyền thị xã, thành phố thuộc tỉnh trước yêucầu của xã hội, của đất nước, tổ chức và hoạt động của chính quyền thị xã, thành phố thuộctỉnh ở nước ta hiện nay vẫn còn những hạn chế, yếu kém nhất định. Điều này làm hạn chếsự phát triển, năng động của các thị xã, thành phố thuộc tỉnh hiện nay, dẫn đến chưa thựcsự đáp ứng được những yêu cầu đổi mới quản trị quốc gia theo hướng hiện đại, hiệu quả.
Nâng cao chất lượng nguồn nhân lực pháp luật
Authors: Vũ Đức Hạnh
Published: October 2023

Xây dựng nền tư pháp trong sạch, vững mạnh, dân chủ, nghiêm minh, bảo vệ công lý, hiệnđại, chuyên nghiệp phục vụ Nhân dân, phụng sự Tổ quốc tất yếu đòi hỏi phải có nguồn nhânlực pháp luật có chất lượng và đủ về số lượng. Để đáp ứng được yêu cầu trên, nhân lực phápluật cần nắm vững chủ trương, đường lối của Đảng và chính sách, pháp luật của Nhà nước;có kiến thức chuyên môn, nghiệp vụ tư pháp vững vàng; có phẩm chất liêm chính, côngminh, chuyên nghiệp; có bản lĩnh chính trị, có đạo đức và trách nhiệm nghề nghiệp; có kiếnthức kinh tế - xã hội và kinh nghiệm thực tiễn; tư duy pháp lý mang tính mở, hệ thống, liênngành; có khả năng tự học và thích ứng nhanh với những biến động của đời sống xã hội vàcông việc, trình độ ngoại ngữ cũng như các kỹ năng bổ trợ khác.
Triển khai thực hiện chính sách, pháp luật về hỗ trợ doanh nghiệp nhỏ và vừa
Authors: Vũ Thị Tuyết Loan
Published: October 2023

Hỗ trợ doanh nghiệp nhỏ và vừa là chủ trương, chính sách đúng đắn và phù hợp của Đảngvà Nhà nước nhằm giúp các doanh nghiệp nhỏ và vừa vượt qua khó khăn, thách thức, có thểđứng vững và phát triển, góp phần thúc đẩy kinh tế - xã hội đất nước phát triển. Từ khi LuậtHỗ trợ doanh nghiệp nhỏ và vừa có hiệu lực, Chính phủ, các bộ, ngành đã ban hành nhiềunghị định, thông tư, trong đó Nghị định số 80/2021/NĐ-CP là hoàn chỉnh, thể chế hóa đầyđủ các quy định của Luật Hỗ trợ doanh nghiệp nhỏ và vừa. Quá trình triển khai thực hiệnNghị định số 80/2021/NĐ-CP đến nay đã đạt được nhiều kết quả tích cực nhưng vẫn cònkhông ít hạn chế, khó khăn. Bài viết có góc nhìn khái quát thực tiễn triển khai thực hiện Nghịđịnh và một số kinh nghiệm rút ra.
The European energy crisis of 2022 in the context of increasing sanctions pressure on the russian federation: Analysis of economic losses and scenarios
Authors: Cui Lianbiao
Published: October 2023

In recent years, European countries have become much more dependent on energy supplies from the russian federation, and this trend has become particularly evident since the onset of the COVID-19 crisis and the full-scale invasion of Ukraine. Therefore, it is relevant to consider the causes and consequences of this crisis for European countries. Thus, the purpose of the study was to demonstrate the likely losses for the EU member states from the onset of the crisis and to formulate possible outcomes. The main scientific method in the investigation was analysis. However, other methods were used, including statistical (graphical, modelling), historical, deduction, etc. The paper analyses foreign trade relations between the russian federation and European countries, which have significantly strengthened over time. The author shows that the EU countries are experiencing a rapid trend of increasing dependence on russian energy resources. The article argues that the consequences of this crisis for the European Union may vary greatly depending on how actively other countries will help to overcome it, especially in terms of oil supplies. With regard to natural gas, it ultimately depends on the policy that EU member states choose to implement to replace this resource in their energy system and how quickly they can respond to the constant new challenges in this area. In any case, the crisis will be followed by rising energy prices, stagflation, and lower economic growth. The article brings new knowledge to the study of the energy market and is of empirical importance for understanding the development trends in Europe and the global economy as a whole
Synthesis and Antibacterial Activity of New Amide Derivatives of Pyrimidinediones
Authors: Nygi Mary , Priya L. Aruna , Devi Shalini , Prashanthi B. , Kalyani S.
Published: October 2023

A series of ten new pyrimidinedione derivatives (4a-j) was synthesized from a common scaffold, 1-(((benzyloxy) carbonyl)methyl)-1,2,3,4-tetrahydro-2,4-dioxopyrimidine-5-carboxylic acid (2). The compound (2) was subjected to acid– amine coupling with different amines 3(a-j). The coupling reaction was performed using HATU as a coupling reagent at room temperature for 3h using the base N-methylmorpholine and solvent DMF. The desired derivatives were obtained with good yields. The synthesized compound’s purity was determined by HPLC analytical techniques. The structures of the pyrimidinediones were analyzed by Fourier-transform infrared spectroscopy, proton nuclear magnetic resonance (1H NMR), 13C NMR, liquid chromatography–mass spectrometry, and Human Resource Management System data. All ten amide derivatives were tested for antibacterial efficacy using Staphylococcus aureus (Gram-positive strain bacteria) and Pseudomonas putida (Gram-negative strain bacteria). Compounds 4g as well as 4h showed significant antibacterial effectiveness, with good minimum inhibition concentration values. A molecular docking study was also performed with the protein 3FQO selected from the Protein Data Bank. The amide compounds 4g and 4h displayed good docking scores. The results of the in silico study complemented the antibacterial effectiveness of the two analogs 4g and 4h. The presence of electron donating groups in these target molecules may be attributed to their high efficacy.
New Thiosemicarbazide Analogs as Antagonist of Nicotinic Muscarinic Receptors: Synthesis, In silico, and In vivo Screening
Authors: Jindaniya Varsha , Mishra Rakhi , Mazumder Rupa , Mazumder Avijit , Kapoor Bhupinder , Khan Fahad
Published: October 2023

Some new thiosemicarbazide derivatives (5*a-5*b and 6a-6f) were synthesized by multiple steps approaches starting from substituted anilines. The synthesized compounds were evaluated for their muscle relaxant activity by an in silico docking study against nicotinic muscarinic receptor (protein database [PDB] ID: 2XNU) using AutoDock Vina and Biovia discovery studio tools. The rotarod test was also used to evaluate the muscle-relaxing activity of the compounds. The results were compared with generic diazepam to corroborate both research findings. In the in silico test, all the compounds showed 2–4 interactions with the target nicotinic muscarinic receptor (PDB ID- 2XNU) having binding affinities in the range of −5.8–−7.8 Kcal/mol. Among them, the 6a compound demonstrated the most remarkable relaxant activity with four hydrogen bond interactions with amino acids TYRC: 52, ILE C: 88, ALA C:90, and GLN C:119 of the target molecule. In addition, the rotarod test showed that compounds 5*a and 6d also had more muscle-relaxing effects than diazepam.
p-TSA-Promoted Efficient Synthesis of Some New Thiophene Hybridized Thiadiazolyl Schiff Bases as Antibacterial Agents
Authors: Mishra Geeta , Dwivedi Parmesh K. , Verma Neeraj , Srivastava Sajal , Singh Ashok K. , Chaturvedi Devdutt
Published: October 2023

A new series of thiophene hybridized thiadiazolyl Schiff bases was designed and synthesized employing FeCl3-mediated cyclization of thiosemicarbazoneinto thiadiazoles and their subsequent Schiff bases formation using p-TSA in benzene. To understand the interaction of the proposed compounds with β-lactamase (Protein Data Bank [PDB] ID: 3UDI), a molecular docking was performed. All the compounds demonstrated an optimal binding affinity with β-lactamase (−8.17 to −9.75 kcal/mol) and showed crucial hydrogen bonds and π–π interaction with the leading amino acids Arg298, Ala300, and Val391 located at the active site of β-lactamase. The in vitro antibacterial activity of the desired molecules was conducted against few gram-positive and Gram-negative bacterial strains using amoxicillinas reference drug. The compound having p-hydroxyphenyl substituent (3c) was found to be potentially effective to inhibit P. aeruginosa and E. coli with MIC value 7.5 μg/mL and 9.0 μg/mL, respectively, whereas other compounds exhibited moderate to good activity. Altogether, the primary in-vitro screening of newly synthesized thiophene hybridized thiadiazole Schiff bases opens a new venture towards the development of promising alternatives of β-lactamase inhibitors as anti-bacterial agents.
Investigating the Dimensions of Mind Perception
Authors: McMurtrie Brandon Luke
Published: October 2023

Mind perception is the ability to infer the presence of a mind in other beings or non-living things (e.g., a tree, an animal, a robot) and make judgements about what "kind" of mind that being possesses. Research has shown that there is a dimensionality to the schema of mind perception, though the number of dimensions is debated. The present study aimed to explore the dimensions via a mind perception scale that measures participants’ perceptions of mental capacities (n = 181). The data was highly suited for factor analysis, so principal axis factoring and multiple criteria were used to find the retained factors. Findings suggest a two-dimensional model of mind perception, supporting the field’s landmark study by Gray et al. (2007).
PENERAPAN MODEL PROJECT BASED LEARNING PADA PEMBELAJARAN INSTALASI TENAGA LISTRIK KELAS XI TITL 1 DI SMK NEGERI 5 MAKASSAR
Authors: Alam Aldiansyah Nur , Mappeasse Muhammad Yusuf , Darmawang Darmawang , Mardiana Mardiana
Published: October 2023

Penelitian ini bertujuan untuk mengetahui peningkatan hasil belajar dan keaktifan dan minat siswa pada mata pelajaran Instalasi Tenaga Listrik (ITL) melalui model pembelajaran Project Based Learning (PjBL) kelas XI TITL-1 di SMK Negeri 5 Makassar. Penelitian ini merupakan penelitian tindakan kelas dengan model yang dikembangkan oleh Kemmis dan Mc Taggart. Subjek penelitian ini adalah siswa kelas XI TITL 1 Semester genap Tahun akademik 2021/2021 dengan jumlah 29 siswa. Penelitian ini terdiri dari dua siklus dengan dua kali pertemuan pada tiap siklus. Teknik pengumpulan data pada penelitian ini menggunakan observasi, tes hasil belajar, dan dokumentasi. Teknik analisis data yang digunakan adalah analisis deskriptif kualitatif. Hasil penelitian menunjukkan bahwa penerapan model pembelajaran Project Based Learning (PBL) pada mata pelajaran ITL dapat meningkatkan hasil belajar, Minat dan keaktifan siswa kelas XI TITL 1 di SMK Negeri 5 Makassar. Hal tersebut dapat dilihat Berdasarkan hasil pengamatan pada setiap pertemuan, pada siklus I pada 73,54%. Pada siklus II meningkat menjadi 81,3%. Rata-rata keaktifan belajar siswa per siklus meningkat dari 83% pada siklus I menjadi 90,17% pada siklus II, dimana saat Pre-Test prosentase minat berdasarkan angket yang diberikan kepada siswa hanya sebesar 67,45 % dan keaktifan hanya sebesar 66,5%. Berdasarkan hasil posttest dan praktik pada siklus I dan siklus II, hasil belajar siswa siklus I menunjukkan rata-rata kelas sebesar 76,38 dan 92,75.
Nivel de depresión y ansiedad durante la pandemia en estudiantes de la escuela profesional de Estomatología de la Universidad Privada San Juan Bautista, Lima, 2021
Authors:   , Torres Ibla Julieth Stephanie
Published: October 2023

Objetivo: Determinar la asociación entre el nivel de depresión y ansiedad durante la pandemia en estudiantes del Programa académico de Estomatología de la Universidad Privada San Juan Bautista, Lima, 2021. Materiales y métodos: El diseño de la investigación fue no experimental, de tipo analítico, transversal, prospectivo y observacional, la muestra estuvo conformada por 140 estudiantes de quinto a décimo ciclo, la cual se estimó mediante una fórmula probabilística para una proporción , se utilizó como técnica de recolección de datos una encuesta elaborada en la plataforma de Google Forms, el cuestionario fue validado mediante juicio de expertos, que contó con tres partes divididas en: datos sociodemográficos, 5 preguntas de indicadores de depresión mediante la Escala de psicopatología depresiva (EPD-6) y 7 preguntas de indicadores de ansiedad mediante Escala de trastorno de ansiedad generalizada (GAD-7). Para el análisis estadístico univariado se usó frecuencias absolutas y relativas. En el análisis estadístico bivariado se utilizó la prueba de Chi cuadrado, se analizó con un nivel de significancia del 95% para un valor p < 0,05. Resultados: Al analizar los niveles de depresión se observó que el 27,9% presentaba síntomas de depresión y con respecto al nivel de ansiedad el 35% presentaron ansiedad leve, el 22,1% ansiedad moderada y el 8,6% ansiedad severa. Conclusiones: Con respecto al análisis bivariado se aplicó la prueba estadística de Chi cuadrado encontrando que existe una asociación significativa entre las dos variables (p=0,00), además se observó que el 72.1% no presentaban síntomas de depresión y el 34.3% no presentaron niveles de ansiedad.
The Effects of Consumers, Competitors and E-Commerce Intensity on Business Performance in Malaysia
Authors: Fei Teddy Lian Kok
Published: October 2023

The growth in electronic commerce in Malaysia reached a new peak in 2020 with a market value of RM30.2 billion. This paper focuses on the factors that contribute to business performance in Malaysia based on the technology, organization and environment framework. The research included electronic commerce intensity as a mediator and a moderator. The SMART-PLS analyses show that the significant direct factors for business performance are consumer influence, competition influence, and electronic commerce intensity. However, top management’s emphasis on e-commerce and technological competence did not affect business performance. The structural model explained 67.5 per cent of the variance in e-commerce intensity and 66.3 per cent of the variance in business performance. Findings also show that e-commerce intensity significantly mediated competition influence and customer orientation to impact business performance. Furthermore, electronic commerce intensity moderated store presence to produce different levels of business performance. The results of the importance-performance map analysis show that the organization that wants to improve business performance must work to enhance its consumer orientation, counteract the influence of the competition, enhance its e-commerce intensity and enhance its consumer orientation. Finally, the research discusses the theoretical and practical implications of the findings.
Examining i-Sinar and i-Lestari Withdrawals Among Employees Provident Fund (EPF) Members During COVID-19 Crisis
Authors: Abd Ghani Muhammad Amirul Ashraf , Awang Halimah , Ab. Rashid Nur Fakhrina , Yoong Tan Lih , Lung Tan Chin , Apalasamy Yamunah Devi , Subbahi Kama Firdaus , Mansor Norma
Published: October 2023

To cope with the economic hardship induced by the COVID-19 pandemic, the government has allowed for withdrawals from the Employees Provident Fund (EPF) retirement savings account. This paper explored the impact of COVID19 on the employment and income status of EPF members prompted them to make early withdrawals from their retirement savings through the i-Sinar and i-Lestari schemes as well as usage of withdrawals. The nonprobability convenience sampling technique, specifically the snowball technique managed to capture 2,061 respondents via an online survey. Logistic regression revealed younger respondents, those earning a lower income, and those experiencing income reduction were more likely to utilise both schemes compared to their counterparts. Although most withdrawals were put to good use, it raises concern as the early withdrawals can bring negative consequences to individuals, taxpayers, and the government in future. Findings from this study can serve as a useful input in suggesting some improvements towards the EPF retirement savings scheme.
Determining Entrepreneurial Intention Among Undergraduate Students in Malaysia Using the Theory of Planned Behavior (TPB)
Authors: Arshad Azlin Shafinaz , Abdul Rahim Siti Nur Nazmin , Kamall Khan Yasmin
Published: October 2023

One of the main issues many countries face is unemployment. Entrepreneurship has been acknowledged as a means of solving unemployment problems. The study aims to determine the factors influencing the entrepreneurial intention of undergraduate students after having exposure to entrepreneurship subjects. This study adopts a quantitative approach using an e-survey and was distributed to students in one of the higher learning institutions in Malaysia. A stratified sampling method was chosen and only 100 responses can be used for further analysis. The data was analyzed using SPSS. Results of the study show that personal attitude and family influence have a significant relationship with students’ intention to start a business. However, there is no significant relationship between perceived behavioral control and entrepreneurial intention. The study has provided valuable insights for the university to develop more effective entrepreneurship programs besides providing support to those who are passionate to go into business.
A Study of Financial Behavior Among Urban Older Chinese
Authors: Chong Shyue Chuan , Neoh Zun Khan Andaeus , Lee Hui Shan , Mah Pei Yew , Tung Diep Thanh
Published: October 2023

Older Malaysian Chinese has one of the highest mean incomes among the other ethnicity in Malaysia. As these individuals grow older, their savings and retirement fund will dwindle and are insufficient for their spending. As a result, these individuals will seek to earn extra income from investment so that they could save more for their children and lifetime care. However, investment is subject to risk. Thus, this study examines the effect of gender, age, financial satisfaction, financial knowledge, and bequest motives on older Malaysian Chinese financial risk tolerance. In this study, the target sample was those Chinese aged 50 or older residing in Selangor, Malaysia. The data were collected through face-to-face interviews with the purposive sampling method. As a result, the survey covered a sample of 263 completed cases. The multiple regression analysis shows that males with optimal financial knowledge, altruistic personality (unselfish and concern for other people), and variables positively influence older Malaysian Chinese’s financial risk tolerance (risk-taker). At the same time, ages and financial satisfaction variables are negative and significantly influence financial risk tolerance (risk- averse). Lastly, these findings may contribute to the relevant authority, such as retirement fund providers, to formulate a proper long-term plan to ensure Chinese older Malaysians’ individual and family financial stress during retirement.
Implementación y configuración del sistema Open Journal System, como herramienta de gestión editorial en línea para el Instituto Superior Tecnológico Tsa’chila.
Authors: Villarreal Cobeña Ángel Wilson , Mantuano Casual Miguel Ángel , Beltrán Salas William Geovanny , Guamán Chávez Ramiro Enrique , Mendoza Loor José Javier
Published: October 2023

El software seleccionado responde a la intención de adaptar sus procesos a los avances tecnológicos y estándares internacionales que permitan la interoperabilidad con otros sistemas, así como al trabajo cooperativo con el ejemplo de otras revistas de investigación, que trabajan con el mismo software y que facilitaron los datos necesarios para la instalación. De igual forma se corresponde con la política institucional utilización de software libre. Con este trabajo se da seguimiento se da gestión eficiente y unificada de todo el proceso editorial de una publicación seriada, desde la recepción de artículos hasta su publicación e indización online. Instalando, configurando y haciendo las pruebas pertinentes en la implementación del software libre Open Journal System desarrollado por el Public Knowledge Project (PKP), un sistema de gestión editorial en línea. La metodología utilizada corresponde a la realización de actividades que permiten disminuir la resistencia al cambio, siendo estas, las siguientes: la Implementación y la configuración del sistema, edición del código fuente y la parametrización del sitio con los datos proporcionados por el personal de investigación, difundiendo los contenidos e investigación producido del material de articulado con los que cuenta el instituto y la personalización del sistema. En el Instituto Superior Tecnológico Tsa’chila de la provincia de Santo Domingo de los Tsáchilas, como en la mayoría de los institutos y universidades del país, se ha hecho necesario el utilizar las tecnologías de la información para las actividades administrativas para la gestión editorial, permitiendo con ello que toda la comunidad académica, estudiantil, e incluso la sociedad, se vea favorecida con la automatización de los servicios para la gestión y publicación de revistas académicas en línea.
α-HBDH is a Superior to LDH in Predicting Cardiac Injury in Patients with Acute Aortic Dissection
Authors: Zhao Yong-bo , Ma Dong , Wang Xue-Feng , Zhao Yong-bo , Sun Yue , Zhang Yun-Jing
Published: October 2023

Objective: Acute aortic dissection (AAD) has a high rate of mortality and postoperative complications, but fewer indicators can predict postoperative cardiac injury complications. This study aimed to investigate whether α-HBDH is superior to LDH as a predictor of in-hospital mortality and postoperative cardiac injury in patients with AAD. Methods: In this retrospective study, a total of 369 patients from 2015 to 2021 were enrolled and divided into three groups (T1: low, T2: medium and T3: high) based on the tertiles of α-HBDH levels on admission. The relationship between α-HBDH and AAD was determined by correlation analysis and logistic regression model, with the consolidation using Kaplan-Meier and restricted cubic spline (RCS) analysis for predicting the in-hospital death and cardiac injury complications. Last, the relationship between α-HBDH levels and in-hospital mortality and cardiac injury was further verified through subgroup analysis. Results: In the logistic regression model, α-HBDH in the high-level group was 9.869 times that in the low-level group [OR (95CI): 9.869 (2.148-45.349), P=0.003], while this feature was not observed in LDH [OR (95CI): 1.437 (0.342-6.034), P=0.621]. Kaplan-Meier analysis showed that increased α-HBDH levels within 30 days were associated with poor survival within 30 days in AAD patients (log rank test, P<0.01), especially in acute stanford A dissection. RCS showed that 204 U/L was the optimal cut-off value of α-HBDH for in-hospital mortality and postoperative cardiac injury, which facilitated clinical stratification of patients with AAD. Subgroup analysis confirmed a stable correlation between α-HBDH level and hospital mortality and cardiac injury (P>0.05). Conclusion: α-HBDH would be better than LDH in predicting the in-hospital death and postoperative cardiac injury, guiding admission stratification of patients with AAD.
PENINGKATAN PRESTASI BELAJAR AZAS TEKNIK KIMIA DENGAN METODE CERAMAH DEMONSTRASI LATIHAN PLUS KOOPERATIF LEARNING TIPE JIGSAW PADA PESERTA DIDIKKELAS XI KIB SMKN 2 DEPOK SLEMAN SEMESTER 4 TAHUN 2023
Authors: Surip Surip
Published: October 2023

Pendidikan bertujuan untuk meningkatkan harkat dan martabat manusia, melalui pendidikan manusia dapat mengembangkan diri dan lingkungannya sesuai dengan norma-norma yang ada serta untuk hidup dengan layak. Keberhasilan pendidikan dalam pembelajaran sangat dipengaruhi oleh kemampuan dan ketepatan guru dalam memilih dan menggunakan metode pembelajaran. Peserta didik merupakan faktor penting dalam keberhasilan pendidikan, karena jika peserta didik mengalami kesulitan belajar maka secara tidak langsung proses belajar mengajar menjadi terganggu. Metode konvensional berupa ceramah kurang menarik bagi peserta didik dan mempunyai kelemahan yaitu peserta didik merasa jenuh karena proses belajar mengajar terkesan datar yang mengakibatkan peserta didik tidur di dalam kelas, berbicara sendiri dan bermain handphone di dalam kelas yang mengakibatkan minat belajar peserta didik turun. Oleh karena itu penelitian ini menggunakan metode yang bersifat komprehensif yaitu Ceramah Demonstrasi Latihan Plus Kooperatif Learning Tipe Jigsaw (CDLP) yang diharapkan akan dapat memperbaiki kualitas pendidikan. Hasil pembelajaran dengan metode CDLP ini dapat meningkatkan pemahaman siswa terhadap pelajaran kejuruan program produktif menjadi lebih interaktif dan keaktifan siswa meningkat dari 60% menjadi 97 %. Dan prestasi belajar siswa kompetensi azas-azas teknik kimia dapat ditingkatkan dari pra siklus berdasarkan daya serap adalah 83,44% pada siklus I meningkat menjadi 90,7% dan pada siklus II dan meningkat menjadi 93,44 %.
IMPLEMENTASI MODEL PROBLEM BASED LEARNING PADA PEMBUATAN MINYAK KAYU PUTIH UNTUK MENINGKATKAN PRESTASI BELAJAR DAN KARAKTER KERJA PROFESIONAL PESERTA DIDIK KELAS XI KIA SMKN 2 DEPOK SLEMAN
Authors: Surip Surip
Published: October 2023

Pendidikan adalah usaha sadar dan terencana untuk mewujudkan proses pembelajaran agar peserta didik secara aktif mengembangkan potensi dirinya untuk memiliki kekuatan spiritual keagamaan, pengendalian diri, kepribadian, kecerdasan, akhlak mulia, serta keterampilan yang diperlukan dirinya, masyarakat, bangsa, dan negara, Dalam praktiknya, tujuan pendidikan yang telah ditetapkan tidak selamanya dapat tercapai penuh seperti yang diharapkan, karena dipengaruhi oleh beberapa faktor yang mendasar. Berdasarkan pengamatan guru sebagai peneliti, proses pembelajaraan di kelas XI KIA SMKN 2 Depok, belum  menggunakan model pembelajaran yang membuat peserta didik lebih aktif dan kreatif dalam pembelajaran. Sebagian besar peserta didik merasa segan bertanya, menjawab dan  merespon diskusi antar teman. Pada proses pembelajaran guru masih banyak menggunakan metode yang konvesional jika dilihat dari metodenya dan medianya. Tingkat keberhasilan peserta didik dalam penguasaan kompetensi pengetahuan dan kompetensi keterampilan dari nilai yang ada ketuntasan belajarnya hanya mencapai 57 %. Oleh karena itu peneliti bermaksud untuk meningkatkan karakter kerja peserta didik melalui model pembelajaran problem based learning (PBL). Pada penelitian ini dengan metode tersebut dapat meningkatkan prestasi belajar peserta didik dari 74,14 pada siklus I menjadi 97,72 pada siklus II. Penerapan model problem-based learning (PBL) dapat meningkatkan aktivitas belajar dari 60% di Siklus I dan meningkat menjadi 80% pada Siklus II.
PENDEKATAN METODE AGILE POLA SCRUM UNTUK MEMBANGUN APLIKASI PENJUALAN LAMPU HIAS JINJUNYE
Authors: Andri Andri , Prassetya Rudi
Published: October 2023

Jinjunye merupakan perusahaan penjualan lampu hias yang pelaporan pembelian dan penjualannya belum menerapkan sistem komputerisasi. Saat ini, laporan-laporan tersebut dihasilkan secara manual atau dengan pencatatan, dengan akurasi dan presisi yang rendah, dan prosesnya memakan waktu, serta keamanan data tidak dapat dijamin. Kegagalan adaptasi merupakan salah satu penyebab kegagalan pengembangan sistem, sehingga diperlukan suatu metode pengembangan yang dapat merespon perubahan sistem dengan cepat. Salah satu cara untuk menghadapi perubahan perkembangan teknologi adalah dengan metode agile development menggunakan model Scrum. Metodologi pengembangan Agile menggunakan pola Scrum selain memiliki prinsip responsif untuk menangani perubahan. Oleh karena itu, untuk mengikuti perkembangan teknologi dan mendukung peningkatan bisnis, perlu dibuat sistem informasi metode Scrum metode Agile di toko Jinjunye yang bergerak di bidang penjualan lampu, sehingga memperoleh keuntungan yang banyak. manfaat dari implementasi tersebut. Sistem seperti itu dapat meningkatkan operasinya.Sistem dibangun dengan menggunakan Java Netbeans dan database MYSQL. Hasil penelitian menunjukkan bahwa penerapan aplikasi penjualan lampu hias ini dapat meningkatkan kinerja pelanggan dan karyawan serta meningkatkan kemampuan karyawan dalam menjalankan tugasnya. Secara keseluruhan, aplikasi ini informatif untuk merancang proses penjualan produk dan pertumbuhan di masa depan.
ERROR ANALYSIS ON STUDENTS WRITING TASK OF PERSONAL LETTERS
Authors: Ma```la Shofwatul , Ambarini Ririn
Published: October 2023

This study tries to classify and explain the many types of writing errors that were discovered in students' personal letters. The outcomes are ascertained by a qualitative data analysis employing the writing assignments of the students as the source of data. The Surface Strategy Taxonomy is used to pinpoint the errors. The researcher employs comparative analysis to divide the students into several skill levels when gathering data. The goal of this study is to identify mistakes committed by science-majoring eleventh-graders at SMAN 6 Kota Semarang, who number 36 students, in their personal letter assignment. The total of errors are 274 errors were classified in this study, with omission errors (f=131, 47.81%) as the most common. The second commonplace fault category was mis-formation errors (f=127, 46.35%). These categories were followed by addition error (f=9, 3.28%) and mis-order error (f=7, 2.55%). From the above result, we can conclude that the most prevalent mistakes among the learners is omission where they frequently eliminate sort of parts which needed in the full sentences due to the fact lack of English grammar knowledge.
CoViD-19 effects on social-emotional development: impact of early intervention
Authors:   Center for the Health Sciences, UCLA, Los Angeles, CA, Chiappelli Francesco ,   90095
Published: October 2023

Age-appropriate development of social and emotional skills is challenging to a child under standard conditions. The CoVID-19 pandemic has likely influenced the development of social, emotional, and communicative skills. Factors like prolonged lockdowns, restricted peer interactions, and mandatory mask-wearing may have hindered children's ability to learn facial expressions and nonverbal cues. The research evidence discussed in this paper confirms that proposition, and examines in further depth the potential impact of the CoViD-19 pandemic. We also discuss groundwork evidence-based early intervention (EI) practices designed to mitigate the negative effects these unprecedented circumstances may have led to, and how tele-medicine alternatives and Artificial intelligence (AI) can expedite interventional childhood plans. The role of bioinformatics is vital in the compilation and analysis of the vast research in this piece related to CoViD-19, serving as a profound search tool for future research endeavors focused on understanding the long term effects of the pandemic.
PhytoSelectDBT: A database for the molecular models of anti-diabetic targets docked with bioactive peptides from selected ethno-medicinal plants
Authors:   Department of Life Science, Assam University - Diphu Campus, Diphu, Karbi Anglong, ASSAM – 782 462, Roy Susanta
Published: October 2023

It is of interest to assess the effectiveness of bioactive peptides derived from 41 ethno-medicinal plants, classify them according to their anti-diabetic protein targets (DPP-IV, alpha-amylase, alpha-glucosidase, GRK2, GSK3B, GLP-1R, and AdipoR1), and create a web tool named PhytoSelectDBT by using the top seven peptides per target. If one of the target-based medicinal plant suggestions made by PhytoSelectDBT is unsuccessful, alternative target-based possibilities are presented by PhytoSelectDBT for treating the condition and any other related complications. The results provide a useful resource for the management of type 2 diabetes and emphasize the significance of utilising ethnomedical knowledge for the identification of potent anti-diabetic plants and their peptides. We used molecular docking to investigate interactions between anti-diabetic targets (DPP-IV, alpha-amylase, alpha-glucosidase, GRK2, GSK3B, GLP-1R, and AdipoR1) and projected bioactive peptides from 41 ethnomedicinal plants. All bioactive peptides were cross-checked against several databases to determine their allergenicity, toxicity, and cross-reactivity. The presence of B and T cell epitopes was also examined in all simulated digested bioactive peptides for reference. This data is archived at the PhytoselectDBT database.
Design, synthesis and analysis of charged RGD derivatives
Authors:   Bharathiar University, Coimbatore, Tamilnadu, India, Mujyambere Bonaventure
Published: October 2023

In the present study, negatively charged N-Biotin-RGD and positively charged C-Biotin-RGD were designed, synthesized, and characterized with docking analysis. The fixation of MDA-MB-231 cells with formalin made their cell surface neutrally charged thus removing the electrostatic interactions between charged biotinylated RGD derivatives and MDA-MB-231 cells. The results of the binding affinity of biotinylated RGD derivatives against MDA-MB-231 cells showed that N-Biotin-RGD had higher binding affinity than C-Biotin-RGD. The cytotoxic effect was analyzed by incubating charged biotinylated RGD derivatives with live MDA-MB-231 cells. MDA-MB-231 cell surface is negatively charged due to high hypersialyliation of polyglycans and Warburg effect. The results of their cytotoxic activities against live MDA-MB-231 cells were found to be electrostatic in nature. C-Biotin-RGD had an attractive interaction with the MDA-MB-231 cell surface resulting in a higher cytotoxic effect. In comparison, N-Biotin-RGD had a repulsive interaction with the MDA-MB-231 cell surface resulting in a lower cytotoxic effect. Hence, positively charged C-Biotin-RGD is a better cytotoxic agent than a negatively charged N-Biotin-RGD against MDA-MB-231 cells.
Special childhood and special old age in situations of survival and prosperity
Authors:   Help Desk, Berlin, Germany, Khayet L. G.
Published: October 2023

The impact of the global systemic crisis on the situation of disabled people in Russia and Germany, the paradigm shift from the development of adaptability to the education of tolerance, from curative therapy to palliative therapy are analyzed. The system of security and provision of disabled people in Germany is described. The problem of the increasing number of cases of dementia, methods of its prevention and maintenance are considered
National Identity and the Choice of Official Languages: A Case Study of Bilingual Education in Singapore
Authors:   Department of Languages and Cultures, BNU-HKBU United International College, Zhuhai City, Guangdong, China, xtinaliu@foxmail.com, Liu Tianlan , Liu Yu ,   Department of History, The University of Hong Kong, Pokfulam, Hong Kong, jackliuyu@foxmail.com
Published: October 2023

Official languages reflect a country's people and cultures, and the process by which they are formulated provides insight into the country's historical development. In multi-ethnic countries, the diversity of languages represents rich cultural deposits, and each language has become a symbol of its people. However, such diversity can make the formulation of official languages challenging. Singapore serves as a compelling example of this challenge. In this research, I will examine the advantages and disadvantages of adopting English and Mandarin as official languages in Singapore, a multi-ethnic country with a complex linguistic landscape. I will also explore the negative outcomes that can arise from overemphasizing Mandarin in bilingual education. This research will demonstrate that mandatory implementation of a language cannot necessarily improve citizens' national identity, and may even exacerbate centrifugal forces.
Swiss Literature and its Links to the European Literary Tradition
Authors:   Department of Languages and Cultures, BNU-HKBU United International College, Zhuhai City, Guangdong, China, cairongyuhappy@gmail.com, Cai Yuqi
Published: October 2023

This paper provides an in-depth exploration of the interconnectedness of Swiss literature within the larger framework of European literary tradition. Through a comprehensive analysis of Swiss authors such as Herman Hesse, Blaise Cendrars, Jeremias Gotthelf, Peter Stamm, Max Frisch, Charles-Ferdinand Ramuz, and Fleur Jaeggy, it sheds light on the significant influence of European literary movements on Swiss literature. These movements encompass romanticism, modernism, postmodernism, and avant-garde, which have been reflected and reframed through a uniquely Swiss lens. Furthermore, the paper presents a detailed examination of specific Swiss literary works to illustrate shared thematic concerns and stylistic nuances that transcend national and linguistic boundaries. The study underscores the importance of cultural exchange in enriching literary traditions and promotes a deeper understanding of the universal human experiences portrayed within Swiss and European literature.
The Possibility to Apply Community Health Workers in San Cristóbal De Las Casas under the Issues of Diabetes
Authors:   Department of Social Sciences, BNU-HKBU United International College, Zhuhai City, Guangdong, 519000, China, kevliubowen@foxmail.com, Liu Bowen
Published: October 2023

The residents in San Cristóbal de las Casas in Mexico suffer from extreme diabetes problems due to the overselling and overusing of Coca-cola. Under this situation, it is vital for locals to achieve sustainable development by lessening residents from the issue of diabetes. Therefore, this paper would analyze why this situation above happened in San Cristóbal de las Casas. Existing research about San Cristóbal de las Casas mainly focuses on economic development but seldom pay attention to the influence of diabetes and how to help the indigenous people out from a health angle. Therefore, relevant materials would base on comparative study, prospect analysis and data source evaluation and apply research question that is how to solve the problem of diabetes from the perspective of health.
INOVASI PENYULUHAN KELUARGA SAKINAH TERHADAP PENGGUNA DAN PECANDU NARKOBA DI DUSUN TANGGUL DESA BANJAR TANGGUL KEC. PUNGGING KAB. MOJOKERTO
Authors: Solich Moch
Published: October 2023

Sebelum tahun 2012 kondisi keluarga dan masyarakat Dsn Tanggul Desa Banjartanggul Kec Pungging Kab. Mojokerto, normal dan stabil, jikalau ada tindakan negatif sangat kecil. Akan tetapi pada Tahun 2012 dan puncaknya 2015 kejahatan meningkat drastis, dan setelah diteliti diseban banyaknya pengguna narkoba pada masyarakat, bahkan Camat Kecamatan Pungging pada tahun 2015 tertangkap pihak berwajib akibat narkoba. Dan Dsn Tanggul ini memiliki angka ketidak harmonisan keluarga yang sangat tinggi dan perceraian yang menghawatirkan. Hal tersebut disebabkan besarnya penggunaan narkoba. Penelitian    karya    ilmiah ini    menggunakan    jenis    penelitian    Deskriptif Kualitatif. Prosedur penelitian kualitatif yang dilakukan peneliti menghasilkan data deskriptif berupa  kata-kata  tertulis  dan  juga  lisan  yang  berasal  dari  orang-orang (informan/responden)  dan  perilaku  yang  diamati  oleh peneliti.  Hasil dari metode kualitatifdeskriptif  yang  digunakan  oleh  peneliti  disesuaikan  antara  pendapat informan dan pendapat peneliti. Secara umum, ada dua kesimpulan yang bisa penulis gambarkan: pertama, Peran Penyuluh Agama Islam untuk mewujudkan keluarga sakinah pada warga Dsn Tanggul Desa. Banjartanggul yaitu bersinergi dengan yayasan BJSC untuk peningkatan ekonomi melalui bidang usaha: mebeler, Peternakan dan pertanian dan bersinergi dengan Pihak Rumah Sakit Sakinah untuk penanganan rehab Medis. Kedua, Inovasi Penyuluhan keluarga sakinah terhadap pengguna dan pecandu narkoba pada warga  Dsn Tanggul Desa. Banjartanggul yaitu: a). Bersama BJSC memberdayakan warga binaan untuk meningkatkan perekonomian melalui beberapa bidang usaha : Mebeler, Pertanian, peternakan dan lain-lain. B). Peningkatan pendidikan spiritual dengan pengajian dan peningkatan dzikir, Mandi taubat selama 7 hari dan shalat selama 40 hari berturut-turut dengan mendapati takbiratul ihram.
Research on the Application of Women's Book Symbols in Cultural and Creative Products Based on the Perspective of Cultural Experience
Authors: Jiang Li
Published: October 2023

Women's calligraphy, a long-standing Chinese character variant font, has long been loved and cherished for its unique beauty and profound cultural connotations. However, how to combine this traditional culture with modern cultural and creative product design, so that it can be more widely used in modern life, becomes the issue to be explored. Through practice, retaining the original characteristics of the Women's Calligraphy symbol while giving modern design elements, a new cultural and artistic experience can be created.
The Influence of Traditional Chinese Family Customs and Traditions on Family Values
Authors:   Southwest Medical University, China, Chen Lei , Yang Rongping ,   Luzhou Municipal Bureau of Justice，China
Published: October 2023

Since ancient times, family style and family motto have been an important part of China's culture, which not only unites the wisdom of our ancestors but also provides guidance for family members' behavior and the basis for their values. The formation and transmission of family style and family motto is the basis for family continuity and reproduction, but also an important guide and shape for family values. It influences the thought and behavior of family members, shapes the personality characteristics of individuals, and affects the stability and development of society. In this paper, we will start with the importance of Chinese traditional family style and family training, explore its far-reaching influence on modern family values, and on this basis, discuss how to combine traditional family style and family training with modern lifestyle for modern transformation and inheritance, and how to carry out the modern inheritance of family style and family training through the demonstration and leading of family values.
Pengaruh Daya Tarik Wisata, Kualitas Pelayanan dan Harga terhadap Niat Berkunjung Ulang di Wisata Pacet Mini Park Mojokerto
Authors: Muhammad Labib RIfqi
Published: October 2023

This purpose of this study is to understand the influence of  Tourist attraction, Quality service, and Price on Intent to revisit at pacet mini park mojokerto.This research was quantitative research. The research population was pacet mini park mojokerto visitors. This research used sampling technique without certain considerations (Accidental Sampling) to get 100 respondents who made purchases at pacet mini park mojokerto based on age, occupation, and gender. The method of data collection used the questionnaires, observation, and documentations. The method of data analysis used the multiple regression analysis. The result of this research showed that the Tourist attraction, Quality service, and Price simultaneously have significant effect on the Intent to revisit. And partially Tourist attraction, Quality service, and Price have significant effect on the Intent to revisit. The Tourist attraction, Quality service, and Price on Intent to revisit in pacet mini park mojokerto visitors (Adjisted R Square) was 49%.
Pengaruh Media Sosial Instagram dan Kelas Sosial terhadap Perilaku Konsumtif (Studi Kasus pada Karyawan Produktif PT. Moya Kasri Wira Jatim Pandaan)
Authors: Maghfiroh
Published: October 2023

This research aims to determine the influence of social media Instagram and social class, either partially or simultaneously, on consumer behavior. The population in this study were production employees of PT. Moya Kasri Wira East Java Pandaan. The sampling technique used random sampling with a total of 104 respondents. The data collection technique is in the form of a questionnaire. The data analysis technique uses multiple regression analysis. The research results show: (1) there is a positive and significant influence of Instagram social media on the consumer behavior of PT production employees. Moya Kasri Wira East Java Pandaan. (2) there is a positive and significant influence of social class on the consumptive behavior of production employees of PT. Moya Kasri Wira Jatim Pandaan. (3) there is a simultaneous influence of Instagram social media and social class on the consumptive behavior of PT. Moya Kasri Wira Jatim Pandaan production employees