bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the prospects for development of the regional economic systems of border regions (based on the materials of the Trans-Baikal territory)
Authors:   The Siberian State University of Science and Technology named after the Academician M.F. Reshetnev, Avramchikova N. T. , Vinokurtseva E. A. ,   The Siberian State University of Science and Technology named after the Academician M.F. Reshetnev
Published: July 2023

The concept of border region is determined in this article. The issues of specifics of the socio-economic development of the border territories on the example of the Trans-Baikal territory are investigated. Specifics of the essence and special place of the border regions in the national macroeconomic system are revealed. The list of border territorial areas of the Trans-Baikal territory is given and the goals of development of the Far-Eastern border territories are determined. Factors influencing the socio-economic development of border territories in different spheres of the economy are systematized, as well as specific factors limiting the competitiveness of border territories. It is noted that in order to achieve the goals of integrated and sustainable development of the Far Eastern border territories, the formation and retention of competitive advantages over the border territories of neighboring states, the border territories of the Trans-Baikal Territory need to take into account the different nature and nature of factors, taking into account and assessing their cumulative impact when forming forecasts of socio-economic development of the territory. To do this, it is necessary to coordinate the interests of public administration bodies, local self-government bodies of both the local territories of the Trans-Baikal territory and the border territories of neighboring states.
Experience of cooperation of the Heilongjiang free trade zone with the international integration organization CREP
Authors:   The Institute of Russia of the Academy of Social Sciences, Чу Ци
Published: July 2023

Since the entry into force of the Comprehensive regional economic partnership (CREP), it has become the most diverse and dynamic free trade zone in the world. The article is devoted to the study of how the Heilongjiang free trade zone can use its own advantages for active connection to CREP and promoting the high-quality and social development.
Review of the Monograph “LegalTech in the Field of Entrepreneurship”
Authors:   Kutaﬁn Moscow State Law University, Shelmenkov Valentin N. , Gusev Denis A. ,   National Research University Higher School of Economics
Published: July 2023

At present, information and communication technologies are an integral part of our lives; without them it is now difﬁcult to imagine the existence and development of the human world. As a consequence, it should be noted that the rapid informatization of society has led to a phenomenon known as the automation of work processes. Modern jurisprudence also could not avoid this fate, and therefore every day the digitalization of legal activity attracts more and more interest from both legal scholars and those who are far from the legal profession. Performing such routine tasks as drafting contracts, document management, issuing licenses, with the help of artiﬁcial intelligence, the algorithms of which exclude the possibility of professional error, is no longer a fantasy, but a reality towards which humanity is successfully moving. Thus, Legal tech systems have become one of the ways to modernize jurisprudence.
Legislative Regulation of Labor Relations of Professional Athletes and Coaches in Russia: History and Present State
Authors:   National Research University Higher School of Economics, Popov Grigoriy A.
Published: July 2023

The article examines the history of the formation of legislative regulation of labor relations of “special subjects” of labor law of the Russian Federation — professional athletes and coaches (sports subjects), as well as the current state of legal regulation of these relations. The author comes to the conclusion that the regulatory and legal regulation of the labor activity of sports subjects in Russia has a short history, equal to about three decades: until the end of the 80s of the XX century, professional sports were not given due attention by the state, and the relations that existed in this area were not properly regulated, which hindered the development of professional sports and created threats to the violation of the rights and legitimate interests of athletes and coaches. After the collapse of the USSR, the regulatory regulation of labor relations of sports subjects went through several stages, each of which had an invaluable impact on the development of professional sports in the Russian Federation. As a result of “trial and error”, a fairly extensive regulatory framework was created, which made it possible to achieve stability and legality in regulating the work of professional athletes and coaches. However, a number of legal conﬂicts and gaps that need to be addressed still remain.
Analisis Pengaruh Implementasi Standar Akuntansi Pemerintahan Berbasis Akrual dan Kinerja SDM Terhadap Kualitas Laporan Keuangan (Studi Kasus Dinas Lingkungan Hidup Provinsi Sumatera Utara)
Authors: Sari Anita , Wahyuni L Arnida
Published: July 2023

Penulis melakukan penelitian  dengan tujuan memberikan pemahaman mengenai bagaimana pengaruh dari Implementasi standar akuntansi pemerintahan dengan basis akrual juga untuk  mengetahui apakah kinerja SDM akan mempengaruhi kualitas laporan keuangan pada keuangan pemerintah Dinas Lingkungan Hidup Provinsi Sumatera Utara. Peneliti menggunakan kuesioner dalam mengumpulkan data dengan total responden sebanyak 15 responden, dan Analisa menggunakan metode kualitatif dan kuantitaif. Analisis data peneliti menggunakan analisis regresi berganda dalam mengetahui pengaruh pada variable. Uji hipotesis yang digunakan adalah uji statistic test dengan menggunakan aplikasi SPSS IBBM 22. Penelitian ini menggambarkan bahwa implementasi SAP dengan basis akrual dan kualitas laporan keuangan memiliki hubungan yang positif. Peneliti juga mendapatkan hasil bahwa kinerja SDM akan akan memberikan pengaruh pada kualitas dan akuntabilitas laporan keuangan. Untuk lebih meningkatkan kualitas SDM yang unggul perlu adanya Diklat yang mengutamakan praktek di lapangan kerja sesuai dengan kebutuhan SDM, dan juga diperlukan adanya perkembangan pada aplikasi keuangan untuk menungkatkan akuntabilitas dan juga kualitas laporan keuangan.
Evaluation of Medication Appropriateness Index in Cardiovascular Outpatient Clinic: A Cross-Sectional Study
Authors: Al-Share Qusai , Khasawneh Rawand , Rababa’h Abeer , Asfar Fadi , Nidal Yara
Published: July 2023

Background: Older adults often have polypharmacy and multiple
comorbidities. Cardiovascular diseases (CVDs) are the most common
morbidities in older adults and are linked to many adverse drug effects
and drug-related issues. Several patient settings use the medication
appropriateness index (MAI) to assess older adults’ Potentially
Inappropriate Medication (PIM) prescribing. Aim: This study estimated
CVDs outpatient clinic PIM prescribing. It also tested the MAI’s ability
to detect and quantify PIMs in CVD outpatient clinics. Methods: It is a
cross-sectional, single-center, cardiovascular outpatient clinic study.
Demographic, medical, and drug data from 65 years or older patients were
retrospectively reviewed. Two clinical pharmacists randomly selected 70
patients and assessed medication appropriateness using the MAI.
Statistical Package for the Social Sciences (SPSS) descriptive and
logistic regression analyses calculated the number of potentially
inappropriate medications, the percentage of patients with inappropriate
medication prescribing, and factors associated with inappropriate
medication prescribing. Results: Total of 87.14% of participants had
PIMs. Two clinical pharmacists evaluated 539 prescriptions, and 59.9%
had an MAI weighted score of zero (no prescription error). Drug-drug
interaction, duplication, and drug-disease interaction almost perfectly
agreed among raters. The two raters’ MAI criteria kappa coefficient was
0.44, indicating moderate agreement. The results showed that only some
medications significantly affected MAI-defined inappropriate
prescribing. Conclusion: The MAI is a reliable and valid tool in CVD
outpatient clinics. A relatively high prevalence of PIMs was found in
the studied population. It mandates implementing specific measures to
reduce PIMs.
Unique Christian Therapeutic Counseling: Maximizing Results and Shortening Time
Authors: Purba Royal Evendi , Gultom Junifrius
Published: July 2023

This article describes Christian therapeutic counseling that can help make the counseling process effective. The purpose of Christian therapeutic counseling is not only to want someone to experience recovery from the problem, but above all, the result of the counseling is that the counselee experiences the likeness of Christ who healed him. To get to that stage, one must start with a change in life because one has been freed, freed, recovered, and has personally met God and experienced the likeness of Christ. This can be called unique counseling, maximizing results and shortening time. The research method used is descriptive qualitative. The study's results stated that Therapeutic counseling impacts the process of believers becoming in the image and likeness of God.  Counselors must synergize with other fields with different gifts, including the local Church, discipleship team, mission, and pastoral because synergy helps perfect a counselee's recovery and shorten the time.
O papel da cultura organizacional na transformação digital
Authors: Inácio Bruno Richard , Rolim Rebeca Barreiros , Serralvo Francisco Antonio
Published: July 2023

A pandemia de COVID-19 impulsionou rapidamente a transformação digital nas organizações, exigindo adaptações nos processos de gestão e inovação. O trabalho remoto se tornou essencial, levando os funcionários a utilizar tecnologias digitais para manter as atividades laborais. No entanto, a transformação digital enfrenta desafios relacionados à cultura organizacional e à resistência à mudança. A liderança desempenha um papel crucial ao promover a inovação e facilitar a adoção de novas tecnologias. A gestão de mudanças é essencial para reduzir a resistência e minimizar a perda de produtividade durante a transição. A resiliência organizacional é fundamental para aproveitar os benefícios da transformação digital, incentivando a aprendizagem contínua e a abertura para novas formas de trabalho. A cultura organizacional e a identidade coletiva devem ser alinhadas com a inovação digital para garantir o sucesso da transformação nas empresas.
Emesis induction is successful for recovery of gastric foreign objects in cats
Authors: Fischer Christiana , Chalifoux Nolan , Reineke Erica
Published: July 2023

OBJECTIVE

To prospectively assess the efficacy of emesis induction for the recovery of gastric foreign objects in cats and to determine if any factors influenced recovery.

ANIMALS

22 client-owned cats.

PROCEDURES

Cats for which emesis induction was deemed appropriate were administered an emetic agent by the attending clinician between October 2018 and April 2021. Data collected included whether emesis was successful in recovery in some or all of the foreign object, time from administration to emesis, number of emetic events, and type, length, width, and surface area of the material ingested.

RESULTS

Of the 22 cats that had emesis attempted, 11 (50%) vomited some or all of the foreign object. The time from ingestion to presentation, time from the last meal, presence of food in the vomitus, type of the object, and length, width, and surface area of the object did not influence the likelihood of successful recovery with emesis induction. The most common object cats ingested were rubber bands.

CLINICAL RELEVANCE

Recovery of gastric foreign objects in cats with emesis induction alone may be successful 50% of the time. The type and size of the object is unlikely to influence whether or not emesis will be successful. This information can help prepare cat-owners for expectations and outcomes following attempts at emesis induction.
Strategic Culture and the Russian Federation’s Engagement in the Russia-Ukraine Conflict
Authors: Kogoj Mark
Published: July 2023

The paper examines Russia’s strategic culture and its behaviour in Russia Ukraine conflict between February 2014 and February 2023. It identifies and examines traditional elements of Russian strategic culture, such as territorial expansionism, a tendency towards offensive military action, the perception of the use of military force as an appropriate means to achieve political goals, a paranoid threat perception - the image of the besieged fortress and distrust of the West, fear of coloured revolutions, and the idea of Russia’s greatness and pursuit of international great power status. As the article shows, traditional elements of Russian strategic culture are reflected in and explain Russian Federation’s behaviour in the Russia Ukraine conflict. This pattern confirms the continuity within Russian strategic culture, as its traditional elements are still present and define the contemporary strategic culture of the Russian Federation.
Corrosive synergic effects of acetic acid and atmospheric pollutants on lead and zinc
Authors: Reiser M. , Sihlovec F. , Beaudouin-Goujon L. , Kouřil M.
Published: July 2023

The aim of this paper was to evaluate the possibility of presence of the synergic corrosive effect between acetic acid and chosen air pollutants such as: Cl2, SO2, NaCl, H2S, NH3, NOx. The metals chosen for following experiments were lead and zinc as they are known to be sensitive to volatile organic compounds. Acetic acid occurs often at indoor environment, where other pollutants may be present. The idea was to describe the influence of other pollutants on increasing the corrosion aggressivity of atmosphere contaminated by acetic acid. Synergic effect was found on lead for following pollutants: sulphur dioxide, chlorine, ammonia and nitrogen oxides. And on zinc the found pollutants are: sodium chloride, sulphur dioxide, chlorine, hydrogen sulphide and nitrogen oxides.
ACOUSTIC PROPERTIES OF HIGHLY ELASTIC POLYURETHANE FOAM VAPEN HR 3744
Authors:   University of Kragujevac, Faculty of Mechanical and Civil Engineering in Kraljevo, Department of Production Engineering, Dositejeva 19, 36000 Kraljevo, Serbia, Pajović Stefan , Radičević Branko ,   University of Kragujevac, Faculty of Mechanical and Civil Engineering in Kraljevo, Department of Production Engineering, Dositejeva 19, 36000 Kraljevo, Serbia, Miodragović Tanja ,   University of Kragujevac, Faculty of Mechanical and Civil Engineering in Kraljevo, Department of Production Engineering, Dositejeva 19, 36000 Kraljevo, Serbia, Perić Jovana ,   University of Kragujevac, Faculty of Mechanical and Civil Engineering in Kraljevo, Department of Production Engineering, Dositejeva 19, 36000 Kraljevo, Serbia
Published: July 2023

Within this research, testing of the acoustic properties of polyurethane foam samples was conducted. The measurement of the absorption coefficient was performed using the transfer function method in an impedance tube, according to the SRPS EN ISO 10534-2:2008 standard. The tested samples represent highly elastic polyurethane foam of low density, with sample thickness ranging from 10 mm to 100 mm. The research results indicate the potential application of polyurethane foam in areas that require efficient sound insulation or noise control, particularly in the mid-frequency range. Therefore, polyurethane foam can be considered an excellent material with acoustic properties that exceed expectations within the given frequency range.
Results of application of the technique of the extraperitoneal closure of loop intestinal stoma
Authors: Maistrenko N. A. , Sazonov A. A. , Romashchenko P. N. , Zotov M. V.
Published: July 2023

The OBJECTIVE was to evaluate the efficacy and safety of the original technique of extraperitoneal closure of a loop intestinal stoma.

METHODS AND MATERIALS. A comparative analysis of the results of surgical treatment of 80 ostomy patients who underwent reconstructive and restorative interventions was carried out. The main group included 40 patients operated on according to the original method of extraperitoneal closure of the intestinal stoma. The control group consisted of 40 patients who underwent restoration of the intestinal tract continuity using a standard method with intra-abdominal access.

RESULTS. The incidence of postoperative complications in the main and control groups was 10 % and 22.5 %, and the failure of the intestinal anastomosis was 5 % and 7.5 %, respectively (p>0.05). After applying the original technique, this complication in no case led to the development of peritonitis, and the closure of the intestinal fistula was achieved by local treatment. In two patients of the control group, anastomosis failure led to the development of peritonitis, which required relaparotomy with separation of the anastomosis and reformation of the stoma, which prevented the goal of hospitalization from being realized. In the main group restoration of intestinal continuity was achieved in all patients.

CONCLUSION. The use of the original technique for extraperitoneal closure of loop intestinal stoma can reduce the incidence of complications, prevent the development of peritonitis in case of anastomosis failure, creating prerequisites for increasing the efficiency of the reconstructive and restorative stage of treatment.
Analyzing the efficiency of the use of current assets of dairy cattle breeding under digitalization
Authors: PARFENOVA Kseniya A.
Published: July 2023

Subject. The article addresses the use of current assets of dairy cattle breeding.
Objectives. The aim is to analyze the efficiency of current assets usage in dairy cattle breeding, give recommendations on optimizing the use of current assets in conditions of digitalization of production processes. The tasks include reviewing the efficiency of current assets of agricultural organizations of the Republic of Tatarstan over the past five years, identifying problems in efficiency evaluation, taking into account the specifics of production, developing a balanced system of indicators to evaluate the efficiency of current assets usage of dairy cattle breeding under enterprise digitalization.
Methods. The study employs general scientific methods, i.e. systems approach, comparison, systematization, and generalization of data.
Results. I developed a balanced system of indicators to evaluate the effectiveness of the use of current assets of dairy cattle breeding in the context of digitalization of enterprise activities subject to specifics of organization's work and information needs of management. The system enables to implement the deviation control principle in practice.
Conclusions. The implementation of proposed recommendations on assessing the effectiveness of use of current assets will help the management of agricultural organizations to make management decisions, taking into account possible financial risks, and to promptly monitor the use of organization's assets in the future.
IE System in Modern Japanese Society
Authors: Devi Rima
Published: July 2023

This paper explores the transformation of the traditional family system in Japanese society, known as the IE system, to a modern family structure influenced by Western ideologies. Historically, the Japanese state was conceptualized as a family state or kazokukokka, with the emperor as the head of the family, as seen in the Meiji Constitution. However, after Japan's defeat in World War II, the allied governments abolished this system, leading to gradual changes in the societal structure. The objective of this research is to investigate how Japanese people have adapted their family system from the traditional IE system to a modern one. The study utilizes a descriptive qualitative approach, employing field research reports and literature related to the contemporary Japanese family system. Data was collected and analyzed using descriptive methods to draw conclusions. The findings of the research highlight that while the IE system was officially removed from the Japanese Constitution, its influence persists in certain aspects of modern Japanese society. Scholars widely agree that remnants of the traditional family system still endure due to the lack of a viable replacement. Eradicating a deeply rooted cultural tradition developed over centuries proves to be a challenging task. This study sheds light on the coexistence of traditional and modern elements within the Japanese family system, presenting a nuanced understanding of how the IE system continues to partially shape family dynamics in contemporary Japanese society.
CURRICULUM MANAGEMENT STRATEGIES AND EFFECTIVE IMPLEMENTATION OF UNIVERSAL BASIC EDUCATION IN NIGERIA
Authors: Abdullahi Nimota Jibola Kadir
Published: July 2023

The main goal of this research was to investigate how curriculum management strategies affected the successful implementation of Universal Basic Education. Total of 712 participants were chosen using proportional random sampling from the sampled primary and junior secondary schools in North-west, Nigeria. The findings of the study demonstrated that students’ mastery goal, effective classroom instruction and evaluation all helped to improve the effectiveness  of UBE implementation.  Pearson product moment correlation coefficient and linear regression analysis were used to test the hypotheses. Thus, it was recommended that school managers should  encourage students' mastery goal so as to help learners to better engaged in the learning process. Likewise, school managers should strive to create effective classroom instruction to help in engaging learner with concepts and process for learning. Furthermore,  evaluation of curriculum and learners activities should be done frequently in order to determine learners’ competence before, during and after instruction toward effective implementation of curriculum.                Keywords: students' mastery goal; effective classroom instruction, evaluation; self-efficacy; curriculum.
Transmembrane transport by platinum-based metal-organic anionophores
Authors: Wang Patrick , Fares Mohamed , Wu Xin , Lewis William , Loeb Stephen , Macreadie Lauren , Gale Philip Alan
Published: July 2023

A series of Pt(II) metal complexes with urea-appended isoquinoline ligands act as efficient transmembrane chloride transporters and operate via classical hydrogen bonding interactions rather than ligand exchange. A number of the complexes exhibited potent transmembrane chloride transport activity.
Resonance Theory and Quantum Dynamics Simulations of Vibrational Polariton Chemistry
Authors: Ying Wenxiang , Huo Pengfei
Published: July 2023

We present numerically exact quantum dynamics simulations using the hierarchical equation of motion (HEOM) approach to investigate the resonance enhancement of chemical reactions due to the vibrational strong coupling (VSC) in polariton chemistry. The results reveal that the cavity mode acts like a ``rate-promoting vibrational (RPV) mode" that enhances the ground state chemical reaction rate constant when the cavity mode frequency matches the vibrational transition frequency. The exact simulation predicts that the VSC-modified rate constant will change quadratically as the light-matter coupling strength increases. When changing the cavity lifetime from the lossy limit to the lossless limit, the numerically exact results predict there will be a turnover of the rate constant. Based on the numerical observations, we present an analytic rate theory to explain the observed sharp resonance peak of the rate profile when tuning the cavity frequency to match the quantum transition frequency of the vibrational ground state to excited states. This rate theory further explains the origin of the broadening of the rate profile. The analytic rate theory agrees with the numerical results under the golden rule limit and the short cavity lifetime limit. To the best of our knowledge, this is the first analytic theory that is able to explain the sharp resonance behavior of the VSC-modified rate profile when coupling an adiabatic ground state chemical reaction to the cavity. We envision that both the numerical analysis and the analytic theory will offer invaluable theoretical insights into the fundamental mechanism of the vibrational strong coupling-induced rate constant modifications in polariton chemistry.
Unveiling the chemical underpinnings behind the enhanced adsorption interaction of NO2 on MoS2, MoSe2, and MoTe2 transition metal dichalcogenides
Authors: Szary Maciej Jan , Radomski Piotr
Published: July 2023

The demand for efficient gas sensors has fueled research into novel materials like transition-metal chalcogenide (TMD) compounds. TMDs such as MoS2, MoSe2, and MoTe2 have shown promise in detecting NO2. However, it remains uncertain which one is best suited for this purpose. Consequently, this study employs computational methods to investigate NO2 adsorption on monolayers of MoS2, MoSe2, and MoTe2. The results show that MoTe2 exhibits the strongest interaction with the highest charge transfer, suggesting its potential for superior NO2 detection compared to MoSe2 and MoS2. The sheets share the same type of outward projecting orbitals and thus the principle model for charge projections. However, the bonding within the sheet influences the accumulation of charge within it, which in turn impacts the availability of electrons on its surface. Subsequently, the mechanism of charge transfer between the TMDs and NO2 remains the same, but more available charge results in an enhanced adsorption interaction. The described mechanism is likely to affect the adsorption of other acceptor-type molecules (e.g., CO2, SO2, H2S, or BF3) and also be behind differences in charge transfer observed among group VI compounds (e.g., MoS2 and WS2).
Cognitive disorders in patients with atrial fibrillation: A review
Authors: Parfenov Vladimir A.
Published: July 2023

Cognitive disorders (CD) represent one of the leading causes of disability among the elderly. Atrial fibrillation (AF) is an independent and corrected risk factor for CD and dementia. The development of CD with AF is associated with the occurrence of cerebral infarcts, silent infarcts, cerebral micro and macro hemorrhages, a cerebral small vessels disease, cerebral hypoperfusion, and comorbid neurodegenerative disease. The prevention of the first and recurrent ischemic stroke (IS) is the leading importance in preventing the development and progression of the CD in AF, which include the use of the vitamin K antagonists (VKA) and new oral anticoagulants (the NOACs apixaban, dabigatran, rivaroxaban, edoxaban), control of arterial pressure and other methods of prevention. The use of the NOACs is more effective than using VKA, reduces the risk of CD and dementia. The use of individual NOACs, various methods for the prevention of CD and Alzheimer's disease in patients with AF are discussed.
Robótica educativa como herramienta para el desarrollo del pensamiento computacional. Una revisión de la literatura
Authors: Mejía Isabel , Ariel Hurtado Julio , Zúñiga Muñoz René Fabián , Salazar España Byron Giovanni
Published: July 2023

El desarrollo de pensamiento computacional viene emergiendo como un área de desarrollo educativo por su relevancia en la resolución de problemas. Sin embargo, es un área que requiere aún de modelos y estrategias para formar estudiantes y evaluar la adquisición de las habilidades relacionadas. Una de esas estrategias es la robótica educativa, en la cual se ofrece una motivación adicional a los niños para la creación y desarrollo de soluciones basadas en software. En este artículo se presenta una revisión de la literatura, en un intento por profundizar en la forma en que varios investigadores perciben la relación entre la Robótica Educativa y el Pensamiento Computacional, mostrando en donde estas dos corrientes confluyen e indagando por la manera en que la primera puede contribuir sobre el desarrollo del segundo. Además, se exponen algunos hallazgos sobre aquellas habilidades de Pensamiento Computacional que se ven afectadas por las actividades con robótica. Finalmente, se abordan algunas críticas relevantes sobre la forma en que estos dos aspectos se integran en la práctica.
Diseño de una metodología basada en imagen para el análisis de la arquitectura muscular
Authors: Heras Sádaba Ángel , Pérez Ruiz Ana , Abizanda Gloria , Calvo Begoña
Published: July 2023

La simulación computacional de la respuesta activa y pasiva del músculo esquelético, mediante elementos finitos, requiere definir con exactitud la orientación de las fibras musculares, pues se relaciona directamente con la fuerza desarrollada por el tejido (Kumagai 2000). En este trabajo se presenta una metodología para determinar la orientación de las fibras musculares de los músculos del manguito rotador de ratón.
Metanación de biogás en reactor de lecho fijo. Influencia de la configuración de la alimentación
Authors: Aragüés-Aldea Pablo , Durán Paúl , Mercader Víctor Daniel , Francés Eva , Peña José Ángel , Herguido Javier
Published: July 2023

En este trabajo se simula la reacción de metanación del CO2 de un biogás, y se comprueban los resultados –en forma de selectividades hacia CO-, para distintas configuraciones de alimentación a un reactor de lecho fijo con tres entradas laterales, determinándose las más adecuadas para llevar a cabo la reacción.
Efecto de la compactación del tumor en la penetración de células del sistema inmune
Authors: Perisé-Badía Ismael , Bayona Clara , Randelovic Teodora , Ochoa Ignacio
Published: July 2023

El objetivo principal de este proyecto es comprender mejor los obstáculos que encuentran las células inmunes al combatir tumores de glioblastoma. Un ejemplo es el alto grado de compactación de estos tumores, que dificulta la penetración de células y fármacos. Este fenómeno puede revertirse con determinados compuestos, como la blebistatina.
El fruto de Opuntia oligacantha var. Ulapa, fuente potencial de fitoquímicos
Authors: López-Palestina C.U. , Santiago-Saenz Y.O. , Gutiérrez-Tlahque J. , Hernández-Fuentes A.D. , Alatorre-Cruz J.M. , Pinedo-Espinoza J.M.
Published: July 2023

Los frutos de Opuntia spp. (xoconostle) son ampliamente consumidos en varias regiones de México, lo que denota su aceptabilidad gastronómica y accesibilidad, por sabor y bajos costos de adquisición. Sin embargo, su calidad nutrimental, y compuestos bioactivos puede cambiar de acuerdo al estado de madurez, condiciones agroclimáticas y variabilidad genética. genética. Es por ello, que el objetivo de esta investigación fué presentar los datos más recientes del xoconostle Ulapa, cultivado en la región de Ulapa de Melchor Ocampo, Hidalgo, México. Se realizó la evaluación de las propiedades fisicoquímicas como, color, sólidos solubles totales (SST), pH y acidez titulable (AT). Se evaluó el contenido de fenoles totales y flavonoides; adicionalmente se determinó betalaínas totales. Los resultados mostraron un alto contenido de betalaínas y flavonoides en comparación con otras especies previamente estudiadas en México. Las concentraciones de estos fitoquímicos presentes en el xoconostle, lo convierten en una fuente permanente y alternativa de compuestos bioactivos.
Representation of textile samples in the context of the virtual collection of a material library
Authors:   UDESC - UNIVERSIDADE DO ESTADO DE SANTA CATARINA, Mardula Emanoela , Maciel Dulce Maria Holanda ,   UDESC - UNIVERSIDADE DO ESTADO DE SANTA CATARINA, Silveira Icléia ,   UDESC - UNIVERSIDADE DO ESTADO DE SANTA CATARINA, Rosa Lucas da ,   UDESC - UNIVERSIDADE DO ESTADO DE SANTA CATARINA, Novelli Daniela ,   UDESC - UNIVERSIDADE DO ESTADO DE SANTA CATARINA
Published: July 2023

This article addresses the digital representation of textile materials, in the context of academic collections. The objective that guided this research was the mapping of possibilities for the digital presentation of fabrics, which attend to their properties and, in this way, meet the demands of users of virtual material libraries. Qualitative and descriptive research was applied with a literature review and a survey of virtual collections of different natures that include a digital presentation of fabrics.
Effects of Gibberellin on Physical and Chemical Quality of Oil Palm (Elaeis guineensis Jacq.) Fresh Fruit Bunches
Authors: Ramanis Imelya , Sudradjat Sudradjat , Saprudin Deden
Published: July 2023

The quality of crude palm oil (CPO) is influenced by the quality of fresh fruit bunches, crop culture, and postharvest handling. A delay in fruit processing can cause physical damages to the fresh fruit bunches. Gibberellic acid (GA3) can potentially reduce the physical damage due to delayed processing of the fresh fruit bunches. Our study aims to determine how GA3 affects the physical and chemical quality of oil palm fresh fruit bunches. The fresh fruit bunch samples were collected from the IPB-Cargill Palm Oil Education and Research, Jonggol, Bogor, Indonesia. This study used a randomized complete block design that consisted of four concentrations of GA3: 0, 12.5, 25 and 37.5 ppm. GA3 application reduced fruit loss, respiration rate, and maintain fruit moisture and firmness, increased the oil content, and stabilize the free fatty acid content. GA3 concentration of 12.5 ppm is the optimal concentration. Based on the correlation analysis, fruit softness has a strong correlation with free fatty acids.
Growth Inhibition Test of Gram and Negative Bacteria in Pharmaceutical Biotechnology Products in the Form of Hand Sanitizer Formulations Based Fermented Telang Flower Kombucha
Authors: Hariadi Hari , Andry Muhammad , Nasution Muhammad Amin , Sumiardi Ade , Rezaldi Firman , Amien Suseno , Ikrawan Yusep
Published: July 2023

Telang flower kombucha is proven to have various pharmacological activities, so that it can be developed as medicines, cosmetics, and its waste can be applied in agriculture as an ingredient in organic liquid fertilizer to support plant development and growth. This research aims to make hand sanitizer gel formulations and preparations with active butterfly pea flowers. Disk diffusion is used to stop gram-positive and gram-negative bacteria from growing. Post hoc analysis and one-way ANOVA were used to analyze the data. The one-way ANOVA analysis yielded results with a significance level of P<0.05, allowing the post hoc test to continue. When tested at a sugar concentration of 40%, the butterfly pea flower kombucha hand sanitizer significantly outperformed the control when it came to inhibiting the growth of the test bacteria. The best way to stop the test bacteria from growing is to use a concentration of 40%.
Modelling private land-use decisions affecting forest cover: the effect of land tenure and environmental policy
Authors:   Motu Economic and Public Policy Research, Timar Levente
Published: July 2023

I use geographic data and discrete choice modelling to investigate private land-use decisions in the context of prominent New Zealand land institutions and environmental policies. Land-use conversions involving gains and losses in planted forests and natural forests are modelled individually. Land under Māori freehold tenure is found to be less likely to be used for pastoral grazing and also less likely to undergo land-use conversion (both to and from a forested use). With respect to environmental policies, results suggest the incentives of the Emissions Trading Scheme did not significantly affect land-use decisions during the sample period of 2008-2016: the carbon reward had little effect on afforestation, and the deforestation liability was largely ineffective at deterring deforestation. On the other hand, the East Coast Forestry Project is found to have increased planted forest area in the district both by encouraging afforestation beyond baseline levels and by discouraging deforestation. Evidence for its effect on regenerating natural forest area is weaker in the data.
Resection interventions in the treatment of hepatocellular cancer in a specialized surgery center
Authors: Pelts V. A. , Tropin V. E. , Shatalin V. A.
Published: July 2023

Background. The relevance of the treatment of hepatocellular cancer (HCC) is determined by a significant increase in the incidence rate and its high prevalence among primary malignant hepatic tumors.The aim of the study. To summarize the experience of providing specialized medical care to patients with hepatocellular cancer.Methods. We studied the direct results of treatment of patients with primary hepatic cancer treated at the Kuzbass Regional Hepatological Center for the period from January 2015 to August 2022. The materials for the study were medical records of patients with an established diagnosis of primary hepatic cancer, surgical records, results of pathohistologic examination. The exclusion criterion was diagnosed cholangiocellular carcinoma.Results. During the period from 2015 to 2022, 59 patients with primary hepatic cancer were treated at the Kuzbass Regional Hepatological Center. Among them, hepatocellular cancer was diagnosed in 48 cases, cholangiocellular cancer – in 11 cases; radical surgery was performed in 12 patients with hepatocellular cancer; fatal outcome was noted in 1 (2.1 %) patient, complications in the postoperative period developed in 5 (41.7 %) cases and were ranked as I-3, IIIb-1 and IVb-1 according to Clavien – Dindo classification.Conclusion. The degree of risk of severe post-resection hepatic failure should be considered one of the main criteria in choosing a strategy for radical surgical treatment. New surgical approaches (laparoscopic vascular isolation of the portal blood flow, using temporary hemostasis in laparoscopic hepatic resections and the device for its implementation) in resection surgery of primary hepatic cancer can improve the immediate results of treatment.
Assessment of the risk of cardiovascular complications in cancer surgery
Authors: Protasov K. V. , Barakhtenko O. A.
Published: July 2023

Cardiac complications of non-cardiac surgeries are an actual and unresolved interdisciplinary problem of clinical medicine today. The incidence of cardiovascular events after non-cardiac surgery is higher than in the general population and does not tend to decrease. The risk of cardiac complications in cancer surgery is the highest. Evidence-based approaches to risk assessment and prevention of cardiovascular events in surgical patients with malignant neoplasms have not been developed. In current clinical guidelines on the prevention, prognosis and treatment of cardiac complications of non-cardiac surgeries, the aspects of this problem in surgical oncology are not considered separately.The aim of this review was to analyze the current sources of literature on the prediction of cardiovascular complications in surgical treatment of cancer patients. The distinctive features of cancer surgery and additional factors causing an increased risk of adverse cardiac outcomes in patients with malignant neoplasms are described. The article presents the results of large cohort studies on the search for reliable predictors of cardiac complications in non-cardiac surgery and on the development of stratification scales and algorithms for preoperative risk assessment. Particular attention is paid to the possibilities and prospects of using these predictive tools in the surgical treatment of cancer. The surgical risks of interventions for malignant neoplasms are described, as well as methods for calculating cardiac risk and functional status assessment that have been validated in oncological patients cohorts. The data of recent studies on the role of serum biomarkers of myocardial damage and increased cardiovascular risk (cardiac troponins and brain natriuretic peptide) in predicting postoperative cardiac events in non-cardiac surgery are presented. Further prospects for the inclusion of biomarkers in risk stratification systems in patients with malignant neoplasms are discussed.
Myocardial damage biomarkers and the first case of macrotroponin I detection in endurance athletes
Authors: Smirnov M. S. , Dorofeykov V. V. , Golberg N. D. , Kurochkina E. V.
Published: July 2023

Background. High levels of cardiac troponin in the blood indicates myocardial injury, including those caused by intense exercises. Recent studies have shown that an elevation in the troponin concentration in the patients can be caused by the macrotroponin circulation. There is no data in the scientific literature describing this problem in athletes.The aim. To identify the cases and possible causes of high blood levels of cardiac markers in athletes before and after endurance exercises.Materials and methods. The study was conducted on 11 male cross-country skiers aged 15–21 years. The study included two stages: the first was conducted at the end of the preparatory period (November, 2020–2021), the second – in the middle (March) of the 2020–2021 competitive period. At each stage, two blood samples were taken from a vein: the first – in the morning on an empty stomach after a day of rest, the second – 12–14 hours after a high-intensity exercise. In the blood serum, the activity of total creatine kinase (CK), weight concentration of the cardiac isoenzyme of creatine kinase (CK-MB), and concentration of high sensitive troponin I (Tn) were measured.Results. The activity of CK in athletes exceeded the upper limit threshold, and decreased from the preparatory (November) to the competitive (March) period. The concentration of CK-MB in response to exercise increased by 2 times and was not accompanied by the signs of myocardial injury. The most sensitive indicator, responsive to physical activity, was troponin I. However, the highest elevation of Tn in blood of one athlete, both before and after the exercise, was associated with the presence of macrotroponin without signs of myocardial injury.Conclusions. An increase of muscle tissue injury biomarkers in blood, including the heart muscle (CK, CK-MB, and Tn), by 2–4 times is a typical reaction for the body of a cross-country skier to an intense exercise. High levels of troponin in the blood, both before and after training or competition, may be associated with the presence of macrotroponin.
The Impact Of The Covid-19 Crisis On Consumer Behavior Online Shopping In Wisma Atlet 2 Quarantine Area, Jakarta
Authors: Febe Marchelina , Ilena Selia
Published: July 2023

This study aims to see whether there is an impact during the Covid 19 pandemic on online shopping behaviour, especially for volunteers and people who are in the quarantine area of Wisma Atlet 2. Where the independent variable of this study is crisis covid 19, which will affect the dependent variable, namely consumer behavior towards online shopping. This research was conducted because currently, Indonesia is experiencing the Corona Virus or more. They are known as Covid 19. Handling and prevention efforts continue to be carried out to fight COVID-19, one of which is by carrying out quarantine both independently and in bulk. One of the places in Jakarta that is used as a place for quarantine is Wisma Atlet 2. Therefore, researchers want to see whether this pandemic can affect someone in shopping online. This research is a quantitative study that uses a questionnaire from Icek Ajzen (Ajzen, 1991) as the main technique of data collection.The results show that online shopping behaviour has increased during the quarantine period.
Profitability: Third Party Funds and Credit Risk Study on Indonesian Digital Banking
Authors: Sidharta Raden Bagus Faizal Irany , Anggriani Rini , Ibrahim Isra Dewi Kuntary , Marchyta Noni Kezia
Published: July 2023

With advances in technological development, people’s needs for fast and readily available services are on the rise. Therefore, many conventional banks started to develop their own brand of digital banking to accommodate these needs. This research is aimed to analyze the effect of third party funds (TPF) toward profitability and credit risk, effect of credit risk toward profitability, and indirect effect of third party funds toward profitability through credit risk by using path analysis method. This research shows that TPF do have a significantly negative effect toward credit risk and similar result of TPF toward profitability, a positive but insignificant effect of credit risk toward profitability, and lastly, TPF shows a direct effect toward profitability, which means that credit risk functioned as a partial mediation effect between TPF and profitability.
Analisis Strategi Promosi dalam Upaya Meningkatkan Kunjungan Wisatawan di Kawasan Wisata Pusuk Sembalun Kabupaten Lombok Utara
Authors: Rahima Phyta , Suriyati Suriyati , Ibrahim Isra Dewi Kuntary
Published: July 2023

Pusuk Sembalun Tourism Park is a natural tourist area that offers a unique view of the slopes of Mount Rinjani, Lombok. The view is dominated by hills, mountains, expanses of rice fields, and traditional houses that have very high historical value. Pusuk Sembalun Tourism Park is located at the foot of Mount Rinjani. The address for the Pusuk Sembalun Tourism Park is on Jl. Jl. Wisata Gunung Rinjani, Sembalun District, East Lombok Regency, West Nusa Tenggara Province (NTB). This study uses the concept of a promotional mix in the form of advertising, personal selling and sales marketing. This study uses a descriptive method using qualitative data. The methods used in collecting data are interviews, observations or coming directly to tourist attractions, and SWOT analysis. The results showed that the form of promotion strategy implemented by Umbul Square Tourism, namely advertising using various TV stations, billboards, and various social media (Instagram, Facebook, YouTube and websites), needs to be implemented in the procurement of waste management according to the category, minimizing use of non-environmentally friendly vehicles. The promotion strategy plays an important role in increasing the number of tourists, the promotional activities carried out by the destination manager are good and need to be improved again so that they are more famous, and tourists want to return to Pusuk Sembalun Tourism
Pengaruh Tambahan Penghasilan Pegawai (TPP) terhadap Kinerja Aparatur Sipil Negara (ASN) pada BPKAD Kabupaten Lombok Barat
Authors: Wardani Rosyia , Helmida Baiq Ertin , Soehartini Baiq
Published: July 2023

This study aims to determine: the application of TPP (additional employee income) and ASN performance at BPKAD West Lombok Regency, as well as the effect of TPP implementation on ASN performance at BPKAD West Lombok Regency. The type of research used in this research is descriptive and associative. The population in this study were all ASN employees at BPKAD West Lombok Regency, totaling 59 employees. The number of samples used was 58 employees with purposive sampling method. The data analysis technique used is descriptive, classic assumption test and simple linear regression. The results showed that the implementation of TPP in the West Lombok BPKAD in terms of Class of Position, Workload and Attendance was in the "Good" category (average 4.09); The ASN's performance at the West Lombok BPKAD was in the "Good" category (4.03). The results of simple linear regression analysis obtained the equation Y = 26.536 + 0.266X and from the results of the hypothesis test the value of t count > t table (4.548 > 1.6715) showed that TPP had an effect on ASN performance at BPKAD Lombok Barat.