bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute Effect of Slow Deep Breathing Maneuver on Patient with Essential Hypertension Stage 1 and 2
Authors: Wiharja Wendy , Pranata Raymond , Fatah Abraham , Bertha Bertha , Kurniadi Ivani C , Deka Hadrian , Damay Vito A
Published: September 2018

Background: Hypertension remains one of the most common health issues in Indonesia. Slow deep breathing maneuver is a non-pharmacological therapy that achieves systolic and diastolic blood pressure lowering effect through sympathetic and parasymphathetic firing rate.Methods: This study was done using cross-sectional design, with consecutive sampling. Sample population was patients with hypertension stage 1 and 2, age range 40-55 years old, who came to Puskesmas Balaraja.Results: Systolic blood pressure lowered from 148.04+5.82 mmHg to 138.15+5.9 mmHg (p<0.05) and diastolic pressure lowered from 85+5.05 mmHg to 78.47+5.46 mmHg (p<0.05). This study showed that there is a relation between the manuever and lowering the systolic and diastolic blood pressure (p=0.000, on T-Test analytical study).Conclusion: Based on the data, the slow deep maneuver can be used as a non-pharmacological therapy for patients with hypertension. Because the effect is acute, it can be considered for hypertension crisis, but further studies are still needed.
Peripartum Cardiomyopathy Reached Progressive Recovery Despites Poor Initial Ejection Fraction
Authors: Sunur Christian , Hermawan Bambang , Apitule Dorothea
Published: September 2018

Peripartum cardiomyopathy (PPCM) is a pregnancy-associated, idiopathic cardiomyopathy secondary to marked left ventricular dysfunction, which manifests between the last month of pregnancy and the first five months postpartum. While it is relatively rare, PPCM is associated with significant morbidity and can be fatal. Its diagnosis is often delayed because its symptoms closely resemble those within the normal spectrum of pregnancy and the postpartum period. When PPCM is misdiagnosed or is not diagnosed in time, the consequences for patients could be deadly. We present a rare case which was first misdiagnosed but had a continuous progressive recovery of LV systolic function (LVSF) within five years after it was finally diagnosed and treated.A 23 year-old female, P1A0, 8-weeks postpartum, was admitted to the emergency unit of our hospital because of dyspnea and fatigue, which developed three days after the delivery of her child. A week prior to delivery she was admitted to the hospital due to coughing, proteinuria and edema of her lower extremities. She was then diagnosed with severe preeclampsia. The patient, however, refused the administration of Magnesium-sulfate as a therapy because of personal reasons. 48 hours later, the patient was induced with oxytocin and she delivered a living female infant via vaginal delivery with no labor complications and was later discharged. Three days after delivery, the patient complained about having shortness of breath and fatigue. She went to a general practitioner who thought her symptoms were normal after a delivery. Two months later she went to an obstetric clinic for a check-up and was referred to the cardiology unit at our hospital. She stated that for the past two months, she had been experiencing symptoms such as exhaustion, palpitations, an inability to lay flat, decreased exercise tolerance and severe dyspnea.PPCM is a rare but potentially lethal disease that remains a challenge to diagnose, prognosticate, and treat. It is increasingly recognized that the condition is often diagnosed late which may indicate a poor prognosis. However, there are cases in which the initial severity of left ventricular dysfunction or dilatation is not necessarily predictive for long-term functional outcome.
Early Repolarization Is Not Always Benign
Authors: Fatullah Iman , El Rasyid Hauda
Published: September 2018

Early repolarization (ER) pattern is marked with J-point elevation, slurring or notching the terminal portion of the QRS and ST segment elevation has been considered benign over the last few decades. However, some reports now suggest a link between early repolarization and increased risk of death due to arrhythmias and idiopathic ventricular fibrillation (VF), known as ER syndrome. Implantable cardioverter-defibrillators implantation and drug isoproterenol are the suggested therapy in patients with ER syndrome. In contrast, patients without symptoms of the syndrome ER are common and have a better prognosis. Risk stratification in asymptomatic patients in the ER remains a gray area. There are still many unanswered questions, so studies exploring the underlying mechanisms of ER continues to be developed.
Panduan Interpretasi dan Pelaporan Angiografi Koroner dengan Tomografi Komputer
Authors: Wicaksono Sony H , Kasim Manoefris , Nugroho J , Zamzami Celly A , Sahara Elen , Gharini Putrika , F Rosi Amrilla
Published: September 2018

Pencitraan kardiak non-invasif dengan teknologi tomografi komputer multi-potongan telah menempati peranan penting dalam diagnosis penyakit jantung dan pembuluh darah. Di Indonesia, penggunaan tomografi komputer kardiak (TKK) telah meluas di kota-kota besar.Panduan yang menjadi standar pelayanan TKK di Indonesia diperlukan agar dokter yang melakukan interpretasi di seluruh Indonesia melaporkan interpretasinya dalam struktur yang seragam sehingga mudah dipahami oleh dokter pengirim. Hal ini menjamin pelayanan terbaik dan keamanan bagi pasien, dokter, dan fasilitas kesehatan, serta menjadi acuan kualitas pelayanan TKK yang berlaku di seluruh Indonesia. Standarisasi ini tentu bermanfaat untuk pendidikan dan penelitian serta penelaahan sejawat.
Perkembangan Implikasi Biologi dan Klinis Proprotein Convertase Subtilisin-Kexin 9
Authors: Sargowo Djanggan
Published: September 2018

Pada tahun 2003 Proprotein Convertase Subtilisin-Kexin 9 (PCSK9) berhasil diidentifikasi.1 PCSK9 berfungsi meningkatkan kadar LDL Cholesterol (LDL-C) melalui degradasi LDL Receptor (LDLR).2 Penemuan PCSK9 telah merevolusi serta merupakan perkembangan terpenting pada bidang riset kardiovaskular satu dekade terakhir, terutama dalam regulasi LDL-C. 1
Role of Traditional Cardiovascular Risk Factors for the Occurrence of Erectile Dysfunction in Patients with Coronary Artery Disease
Authors: Hernawan Heri , Arso Irsad Andi , Maharani Erika
Published: September 2018

Background: Erectile Dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient to permit satisfactory sexual intercourse. Erectile dysfunction affects more than 150 million men worldwide and impairs psychological well-being and personal relationships, hence quality of life. Recent studies have shown that ED is present in 42% to 76% of men with coronary artery disease (CAD). Epidemiological study showed clearly role of traditional cardiovascular risk factors such as diabetes, hypertension, dyslipidemia and smoking in CAD. Erectile dysfunction and vascular diseases share a similar risk factors and pathogenic involvement of nitric oxide (NO)-pathway leading to impairment of endothelium-dependent vasodilatation (early phase) and structural vascular abnormalities (late phase). This study was conducted to determine whether the stable CAD patients who have traditional cardiovascular risk factors has a higher risk for ED compared with stable CAD patients without traditional cardiovascular risk factors.Methods: We performed an age matched-paired case control study. Men with CAD documented by angiography were evaluated for ED. Erectile function was assessed by a 5-item version of the International Index of Erectile Function (IIEF-5). Traditional cardiovascular risk factors such as diabetes, hypertension, dyslipidemia and cigarette smoking were assesed. Depression and anxiety were screened using Indonesian version of Hospital Anxiety and Depression Scale (HADS). Basic demographic and other variables were also collected.Results: This study evaluated 127 men, 96.8% of them had traditional cardiovascular risk factors, 25.2% had diabetes mellitus, 77.2% had dyslipidemia, 55.9% had hypertension and 64.6% were smoker. Traditional cardiovascular risk factors was strongly associated with ED (OR=10.67 [1.25-232.83]). ED was independently associated with diabetes mellitus (OR=4.17 [1.14-15.24]), hypertension (OR=2.64 [1.07-6.49]) and cigarette smoking (OR=2.26 [1.01-5.75]).Conclusion: CAD patients with traditional cardiovascular risk factor had more risk for developing ED than those with no traditional cardiovascular risk factor.
Principles of the 3Rs and ARRIVE Guidelines in Animal Research
Authors: Yurista Salva Reverentia , Ferdian Rafi Andika , Sargowo Djanggan
Published: September 2018

The use of animals in research has concerned the general public and thoughtful researchers for a long time. For improved animal welfare and increased research quality, researchers have moral obligations to include the 3Rs. The Three Rs are basic principles of humane experimental technique that were first set out by Russell and Burch in 1959. They are now widely accepted within the international scientific community and in associated legislation and guidelines, as a means of avoiding or reducing animal use and suffering and helping to improve the quality of science. When reporting animal studies, it is recommended that manuscripts conform to the principals of the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines, incorporated the 3Rs principal.
Cardiovascular and Neurological Complications Associated with Atrial Fibrillation
Authors: Pranata Raymond , Deka Hadrian , Siswanto Bambang Budi
Published: September 2018

Atrial fibrillation (FA) is the most common type of sustained-arrhythmia and one of the leading causes of mortality and morbidity globally, with estimated five million incidents. FA was associated with increased all-cause mortality (RR 1.46), cardiovascular mortality (RR 2.03), major cardiovascular events (RR 1.96), stroke (RR 2.42), ischemic stroke (RR 2.33), dementia (HR 1.42) and cognitive decline, ischemic heart disease (RR 1.61), sudden cardiac death (RR 1.88), heart failure (RR 4.99), chronic kidney disease (RR 1.64), and peripheral artery disease (RR 1.31). Overall, all-cause and cardiovascular mortality increased. Cognitive decline and dementia are also a concern since they impair function and quality of life. Overall, FA has bidirectional association with other cardiovascular diseases hence it acts as a marker for them. Therefore, prevention and control of risk factors are of utmost importance.
Era Jaminan Kesejahteraan Nasional: Tantangan dan Kesempatan untuk Standarisasi Pelayanan Kardiovaskular
Authors: Radi Basuni
Published: September 2018

Cerita dimulai dengan terbitnya Sistem Jaminan Sosial Nasional (SJSN) yang merupakan salah satu bentuk perlindungan sosial untuk menjamin seluruh rakyat agar dapat memenuhi kebutuhan dasar hidup yang layak.1 Sistem ini tentu saja ditunggu oleh berbagai pihak yang mengharapkan peningkatan kesejahteraan masyarakat dengan jaminan sosial dari negara.
Comparison of In-hospital Major Adverse Cardiovascular Events in Patients of Acute Inferior Myocardial Infarction With or Without Precordial ST Segment Depression
Authors: Suganti Jaya , Siregar Abdullah Afif , Hasan Harris
Published: September 2018

Background: The clinical implications of precordial ST segment depression (PSTD) during acute inferior myocardial infarction has been an area of debate, and still under investigation with conflicting results. Based on previous studies, the presence of PSTD defines a high risk subset of patients with acute inferior myocardial infarction due to a more extensive myocardial ischemia that lead to a higher incidence of major adverse cardiovascular events (MACE). Despite of these results, others still considered this ECG finding as a benign electrical phenomenon. The aim of this study is to compare the incidence of in-hospital MACE in patients of acute inferior myocardial infarction with or without PSTD and to know whether PSTD can be used as a predictor of in-hospital MACE in acute inferior myocardial infarction.Methods: A total of 96 acute inferior myocardial infarction patients admitted from December 2013-2015 at Cardiology Department of Haji Adam Malik General Hospital were retrospectively analyzed. Patients were divided into two groups based on the presence of PSTD on admission ECG. Bivariate and multivariate analyses were performed to study the association between PSTD and in-hospital MACE, p value<0.05 was considered statistically significant.Results: The bivariate analysis showed that in-hospital MACE was significantly higher in patients of acute inferior myocardial infarction with PSTD than without PSTD (92% vs 8%, p<0.001). On multiple logistic regression analysis, patients of acute inferior myocardial infarction with PSTD have a 5.4 fold increased risk of in-hospital MACE than patients without PSTD (OR 5.480; 95% CI 1.759-17.067, p=0.003).Conclusion: The presence of precordial ST segment depression on admission ECG in acute inferior myocardial infarction patients was associated with a higher in-hospital MACE and was an independent predictor of in-hospital MACE.
Diagnostic Test Squatting Stress Echocardiography and Coronary Angiography in Diagnosing Coronary Heart Disease
Authors: Rahman Andy , Yanni Mefri , Syafri Masrul
Published: September 2018

Background: In patients with significant coronary heart disease (CHD), increased preload and afterload during a squat can cause wall motion abnormalities (WMA) which can be detected on echocardiography. This study was conducted to determine the diagnostic value of stress echocardiography squatting as a non-invasive examination of a relatively simple, inexpensive, and safe in the detection of coronary artery stenosis in stable CHD and unstable angina patients.Methods: This study was a cross-sectional design. The subjects were all patients with stable CHD and unstable angina whom were treated in Instalasi Pusat Jantung Rumah Sakit Dr. M. Djamil Padang from May to July 2016. Subjects underwent squatting stress echocardiography procedures followed by coronary angiography. Diagnostic test was used to determine the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of squatting stress echocardiography.Results: The sensitivity, specificity, and accuracy of squatting echocardiography for diagnosis of CAD were 90.3%, 88.9% and 89.7%, respectively.Conclusion: Squatting stress echocardiography can be proposed as a non-invasive examination which is relatively simple, inexpensive and safe to detect coronary artery stenosis on patients with stable CHD and unstable CHD.
Role of Omega-3 Fatty Acids in Dyslipidemia and Cardiovascular Diseases
Authors: Fonda Grace , Pranata Raymond , Deka Hadrian
Published: September 2018

Globally, coronary heart disease (CHD) is a leading cause of mortality and morbidity, especially in developing countries. Both marine and plants sources of omega-3 fatty acids has been shown to be beneficial in reducing CHD mortality. Beside of anti-arrhythmic effects, omega-3 has been shown anti-thrombotic and anti-atherosclerotic effect. In 2011, US population spent about 25 billion US dollar for omega-3 supplement; it is projected to be 35 billion US dollar in the year 2016. Several reviews on randomized controlled trial conclude that omega-3 fatty acids reduced plasma triglyceride level consistently in a dose-dependent fashion. Other beneficial effects on blood pressure, endothelial function and high density lipoprotein (HDL) level participate in lowering CHD mortality. American Heart Association (AHA) recommended routine fish consumption as secondary prevention in patient at risk. Omega-3 fatty acids role in primary prevention is inconclusive and need further investigation regarding cost-benefit and bleeding risk.
Serial Case of Twiddler Syndrome
Authors: Wulandari Pipiet , Raharjo Sunu B , Hanafy Dicky A , Haryati Lina , Yuniadi Yoga
Published: September 2018

Background: Twiddler syndrome is an infrequent but potentially dangerous complication of device therapy for dysrhythmias. This syndrome results from manipulation of implanted pulse generator by the patient, leading to traction and subsequent lead dislodgement. It can also occur spontaneously. It has been increasingly reported with pacemaker or implantable cardioverter-defibrillators (ICDs). In this reports, we describe two patients with Twiddler syndrome with substantial retraction of their lead who denied any manipulation of their device.Case Illustration: The first patient was a 56 year-old man with single-chamber ICD due to dilated cardiomyopathy (DCM) with congestive heart failure and severe systolic left ventricular dysfunction (ejection fraction 18%). The dislodged lead causing rhythmical twitching of left pectoral muscles and abdominal pulsations. The second patient was a 69 year-old man with dual-chamber pacemaker due to total atrioventricular block with normal systolic left ventricular function (ejection fraction 70%). It manifested as dyspnea on effort, and he also underwent pacemaker implantation. They underwent primary devices implantation at April 2016 and reposition of generators and its leads in December 2016. The first and second patients denied of manipulating the generator of ICD or pacemaker and rotated their left arm and right arm, respectively, after implantation.Summary: Other unconscious arm abduction during sleep or increased muscular activity of the shoulder and arm might have led to repetitive motions within the pocket and dislodge the device. Adequate individualized patient and family education and regular evaluation every 6 month of the leads position with fluoroscopy or chest X-ray is advisable.
What Is the Cause of Non-responders in CRT and How to Identify It?
Authors: Yamin Muhammad
Published: September 2018

No Abstract
Diagnostic Value of Left Ventricular Early Inflow-Outflow Index in Determining Severity of Mitral Regurgitation
Authors: Yulia Vera , Yanni Mefri , Hariyanto Didik
Published: September 2018

Background: Determining severity of mitral regurgitation (MR) is very important, asit is related with prognosis and management of the disease. Currently, there is no goldstandard exists for quantification of MR severity using echocardiography. AmericanSociety of Echocardiography (ASE) guidelines recommend several parameters basedon integrative criteria using color and spectral Doppler and anatomic measurement.Left Ventricular Early Inflow Outflow Index (LVEIO Index) was proposed as one parameterto assess the severity of MR by omitting geometric error from regurgitantvolume method. Thus, LVEIO index offers a simple, easy and accurate measurementin determining severity of MR.Methods: This study was a diagnostic test research with cross-sectional design. Thesubjects were all patients with organic mitral regurgitation who underwent echocardiographyexamination to measure severity of MR using the LVEIO index as well asother parameters measurements based on parameters of ASE guidelines. Diagnostictest was used to determine the sensitivity, specificity, positive predictive value, negativepredictive value and accuracy of LVEIO index.Results: Of 49 patients in this study, 23 of them have severe MR and 26 are non-severeMR patients. The proportion of gender between two groups almost similar with an agerange from 56 to 61 years and the most common etiology finding was degenerative MR.Echocardiography examination showed the ejection fraction in severe MR was 63±4.2%and 64±3.9% in non-severe MR. The value of LAVI, MPAP, E-wave, VC, EROA andLVEIO index increased parallel with severity of MR (LAVI; 67±18.2 vs. 40±14.2 ml/m2,MPAP; 28±12.8 vs. 20±12.6 mmHg, E-wave 1.5±0.3 vs. 1±0.2 m/s, VC 0.8±0.3 vs.0.5±0.1 cm, EROA 0.4±0.1 vs 0,2±0,1cm2, LVEIO 9±2,4 vs. 5±1,8). The sensitivity,specificity, and accuracy of LVEIO index for diagnosis of severe MR were 86%, 84%,and 89%, respectively.Conclusion: LVEIO can be proposed as a relatively simple, easy and accurate methodin determining severity of MR.
Hypolipidemic Effect and Antioxidant Activity of Tamarind Leaves Extract in Hypercholesterol-Fed Rats
Authors: Aprilia Citra Ayu , Ninditasari Ghina , BR Djoko Walujo
Published: September 2018

Background: Higher cost and side effects made of some anticholesterol drugs usedin long time are the reasons why some people change to herbal therapies. Tamarind(Tamarindus indica) leaves is one of the herbal therapies. This research aims to determinehypolipidemic effect and antioxidant activity of extract of tamarind leaves (ETL).Methods: We used 25 rats as samples, divided into five groups of negative control(CMC 0.5%), positive control (Ezetimibe 1.26 g/kgBW)), first, second and third doseof ETL consequently are 0.93, 1.86 and 3.73 g/kgBW.Results: Paired-samples T-test showed ETL significantly decreased total cholesterol(TC), triglyceride (TG) level, and high-density lipoprotein cholesterol (HDL-C) levelsignificantly increased compared with negative control groups (p≤0.05). Low-densitylipoprotein cholesterol (LDL-C) level had significant difference only at second dose ofETL (p<0.05). Furthermore, the data’s difference between pre- and post-interventionwere analyzed with one-way ANOVA test in TC, TG, and HDL-C level, ETL had asignificant difference (p≤0.05), while there was no significant difference in LDL -Cbetween groups (p>0.05). Data were also analyzed by Post Hoc test. TC, TG, andHDL-C level had a significant difference between all variance ETL’s doses and positivecontrol compared with negative control group (p≤0.05). For antioxidant activity, ETLexhibited the significant reduction in the levels of malondialdehyde (MDA) by pairedsamplesT-test (p≤0.05) but there was no significant difference in both of MDA andsuperoxide dismutase (SOD) level (p>0.05) analyzed by One-way ANO VA test.Conclusion: All variant of ETL’s doses have hypolipidemic effect and antioxidant activity.ETL also has similar effect with Ezetimibe. Saponin, flavonoid, epicatechin, tanin, andpolyphenol that is contained likely contribute to these pharmacologic effects.
Shock Index as Simple Clinical Independent Predictor of In-hospital MACEs in NSTEMI Patients Presenting with Heart Failure
Authors: Handayani Ahmad , Kaban Kartika , Nasri Marwan , Mukhtar Zulfikri , Siregar Abdullah Afif
Published: September 2018

Background: Identification of Non-ST Elevation Myocardial Infarction (NSTEMI) patientsat higher risk of in-hospital complications is very important. Such identification will givecrucial information in determining treatment strategy especially for those come with heartfailure. One of the simple predictor for short term prognosis in acute coronary syndromeis shock index (SI), which is the ratio of heart rate over systolic blood pressure on admission.There had not been any study conducted to evaluate the use of SI in NSTEMI patientscome with heart failure. The aim of this study is to evaluate the SI compared with otherroutine clinical and laboratory examination as a predictor of in-hospital major adversecardiac events (MACEs) in NSTEMI patients presenting with heart failure.Methods: We performed a retrospective analysis of NSTEMI patients with heart failureadmitted to Haji Adam Malik General Hospital in Medan from January 2014 until July 2015.SI was calculated as the ratio of heart rate over systolic blood pressure on presentation.Patients presenting with cardiogenic shock were excluded.Results: There were 55 patients eligible in this study. In-hospital MACEs was found in 24patients (44%) compared with 31 patients (56%) without in-hospital MACEs. Patientswith in-hospital MACEs were older (60.6±10.8 vs. 57.2±7.9, p=0.178), had less historyof dyslipidemia [8(33%) vs. 19 (61%), p=0.032], faster heart rate (111.4±35.8 vs.96.5±24.3, p=0.032], higher GRACE score [139(98-187) vs. 120 (91-148); p=0.001],and higher SI [0.83(0.57-1.5) vs. 0.67 (0.38-1.27), p=0.013). SI >0.8 was the only independentpredictor of MACEs in NSTEMI patients presenting with heart failure (OR=4.3,CI=1.247-14.328, p=0.048).Conclusion: Beyond other routine examinations, SI is the only independent predictor ofin-hospital MACEs in NSTEMI patients presenting with heart failure.
Role of Highly Sensitive Cardiac Troponin T Assay in Stable Coronary Artery Disease
Authors: Pranata Raymond , Kusuma Nico , Vania Rachel , Siswanto Bambang Budi
Published: September 2018

Cardiac troponins (cTn) are the preferred biomarkers of myocardial necrosis, usually used for diagnosis and risk stratification in acute coronary syndromes. Highly sensitive troponin T (hs-cTnT) may be elevated in stable coronary artery disease (SCAD), in which subclinical plaque erosion or rupture and distal embolization and subclinical ischemic episode. hs-cTnT may be used as a prognostic marker in SCAD and can predict cardiovascular events and patient’s mortality rate. In this article, plaque characteristic that is linked to hs-cTnT, it’s used as prognostic biomarker and comparison to other indicators are the focus of discussion.

 

Abstrak

Troponin adalah biomarker yang paling disukai untuk mendeteksi nekrosis miokardium dan untuk mendiagnosis dan stratifikasi risiko pada sindrom koroner akut. Highly sensitive troponin T (hs-cTnT) dapat meningkat pada penyakit jantung koroner stabil dimana terjadi ruptur plak atau erosi dan embolisasi distal sublklinis, dan episode iskemik subklinis. Sehingga biomarker tersebut dapat digunakan sebagai marker prognostik pada penyakit jantung koroner stabil dan dapat memprediksi angka kejadian kardiovaskular dan tingkat mortalitas pasien. Pada artikel ini akan dibahas mengenai karakteristik plak yang dihubungkan dengan peningkatan hs-cTnT, pengunaan sebagai biomarker prognostik dan serta perbandingan dengan indikator lainnya.
CT-FFR: Clinical Application
Authors: Purwowiyoto Sidhi Laksono
Published: September 2018

Invasive fractional flow reserve (FFR) is the gold standard for guiding decision making to identify patients who would benefit from revascularization. Now, computed tomography can also do that by using computational fluid dynamics to calculate fractional flow reserve values from coronary CT angiography image data sets, known as CT-FFR. CT-FFR as an alternative method beside invasive FFR enables the identification of lesion-specific in coronary tree noninvasively. CT-FFR has showed significant improvement in specificity and positive predictive value and decreasing the frequency of using invasive coronary angiography.

 

Abstrak

Pemeriksaan invasif fractional flow reserve (FFR) adalah standar emas untuk memandu pengambilan keputusan dalam mengidentifikasi pasien apakah yang mendapat manfaat dari revaskularisasi. Sekarang, computed tomography juga dapat melakukannya dengan menggunakan dinamika cairan terkomputasi untuk menghitung fractional flow reserve dari kumpulan data gambar angiografi koroner CT, yang dikenal sebagai CT-FFR. CT-FFR sebagai metode alternatif selain FFR invasif memungkinkan identifikasi spesifik lesi pada koroner secara non-invasif. CT-FFR telah menunjukkan peningkatan yang signifikan pada spesifisitas dan nilai prediksi positif dan penurunan frekuensi penggunaan angiografi koroner invasif.
NILAI-NILAI MANTRA BERCOCOK TANAM DI DESA CAMPA KECAMATAN MADAPANGGA KABUPATEN BIMA
Authors: Irwansyah Irwansyah , Arifudin Arifudin , Yusran Kamaludin
Published: September 2018

This study explores the nature of mantra for the rice breeding in Campa Village, Madapangga District the regent of Bima.  As the indigenous people belive on the aesthetical and spiritual of the mantra, this study tries to explore how society especially the villagers who mostly are farmers perceive values in the mantra. This syudy used ethnograpy and approached the data analysis using qualitative methods.  Five informants having authority in the mantra were interviewed and harvesting rice was used as research setting.  Observation, interview and document analysis were the sources of data in this research.  This study reveals that aqidah (God trust) values are the most values people believe as the total renderness to Allah as the absolute truth.  Reying on Allah wish, people involve activities of plantation rice for success. The second value is syariah (law)  from where people rule and apply their social and daily life activities.  The third value is moral (akhlak) to maintain their surrounding in peace, safe and sustainable.
Academic Performance in Community Colleges: The Influences of Part-Time and Full-Time Instructors
Authors: Xu Di
Published: September 2018

Understanding the relative impacts of part-time adjuncts in community colleges is highly policy-relevant, partly because community colleges rely on part-time faculty heavily and partly because community colleges assume a critical role in addressing the national equity agenda by disproportionately serving underrepresented groups. This study uses individual transcript data to explore how initial exposure to a particular field of study with part-time adjuncts influences student performance in current and subsequent course performance in community colleges. To address selection bias, I use two empirical strategies, a two-way fixed effects model and an instrumental variable approach. The results consistently suggest that part-time adjuncts are associated with higher grades in contemporaneous courses but have negative impacts on subsequent course performance.
An ERP-based Guilty Knowledge Test for Sequential Lineups
Authors: Baldassari Mario J. , Lindsay D. Stephen , Holroyd Clay , Tanaka Jim
Published: September 2018

Witnesses to crimes are sometimes reluctant to identify the culprit in a lineup (e.g., for fear of retribution). We introduce an ERP-based guilty knowledge test for sequential lineup identifications, using an oddball paradigm to evoke the P300 component when a witness sees a photo of a culprit compared to those evoked by an innocent familiar face. At the group level, clear differences were found between P300 amplitudes evoked by the culprit’s face and the innocent filler face. At the individual level, the participants’ waveforms were less diagnostic. This method of eyewitness assessment may prove useful if the procedure can be improved in ways that clarify P300 amplitudes for individual participants. Success in this endeavor would be best applied with witnesses who recognize the culprit easily but are compelled to claim falsely that they do not.
The Learning of Angklung in The Learning Culture of Primary Teacher Education Students in Indonesia
Authors: Julia Julia , Iswara Prana Dwija , Supriyadi Tedi
Published: September 2018

Learning angklung ensemble in music major is common, but learning angklung in the environment of student in Primary Teacher Education major is uncommon. This research aims at analyzing the culture of learning angklung in students not majoring in Music, but in Primary Teacher Education. The method used was qualitative method by giving some angklung materials to be studied and performed. During the learning process, the students were observed, then after the show they were assigned to fill the survey to strengthen the findings about their learning culture in studying angklung. The results of the study indicated that students in Primary Teacher Education had high motivation to learn angklung, but did not have sufficient knowledge in basic theory of music, and in practice they had a learning culture that tended to be less able to hold a commitment to learn in groups or work together to perfectly complete an angklung music composition.
IMPLEMENTING JUST A MINUTE GAME IN TEACHING SPEAKING TO AGRIBUSINESS STUDENTS' AT UM PAREPARE
Authors: adriyani
Published: September 2018

This research discuss about an interactive gamet that may use in teaching speaking for the agribusiness students. The game is Just a minute game. The rule of this game is the students speak in one minute without hesitation, repetition, and deviation. If any students break the rule, otomatically they will lose in this game. A timekeeper will ring the bell once the minute is up. The person who is speaking when the bell rings will win 10 points. By using this game, it may improve srategy competence of Agribusiness students in speaking. Communication strategies is the ability of students to overcome the problems in speaking. The trategies may include paraphrasing, substitution, coining new words, switching to the first language, and asking for clarification. Just a minute game is very suitable to aplyed in speaking activities, because this games require all of the students to speak in one minute so they will be active to speak.
Perencanaan Wireless Metropolitan Area Network Kota Tarakan
Authors: Rudy Rudy
Published: September 2018

Penelitian ini menggunakan metode topologi jaringan bintang pada jaringan backhaul. Pada jaringan backhaul ini menggunakan teknologi WiMAX 5,8 GHz hal ini dikarenakan agar dapat menghantarkan bandwidth dengan kecepatan tinggi sehingga dapat menyediakan koneksi internet yang baik dan cepat. Kemudian jaringan WiMAX 5,8 GHz ini dikonversi ke jaringan 2,4 GHz yang kemudian disalurkan ke daerah-daerah dengan metode point to multipoint. Dari hasil penelitian, sel-sel kanal komunikasi WiFi didapatlah hasil yang optimal yaitu dengan memanfaatkan 6 menara yang sudah ada dan dari semua hasil perhitungan link budget pada setiap jaringan maka didapatlah hasil yang optimal yang telah memenuhi standar dan peraturan yang berlaku di Indonesia sehingga para pengguna dapat terkoneksi dengan baik.
Robustless Test Of Several Potato Clon In The Medium Plains
Authors: Aryza Solly
Published: September 2018

Abstract: Expansion Of Potato Plant In Medium Plain Has Geographical Obstacles Concerning With ItsCharacteristics Of Which Requires A Relatively Low Temperature During Growth Stage, Especially At TuberFormation Which Requires The Optimum Temperature Of 180 Oc. Escalating Temperatures Imply A GreaterRate Of Gibberellin Synthesis In Leave Bud And Stolon Tip, And Indicating A Modification Of Stolon Into TuberIs Impaired. Apart From That, Planting Of The Potato In Medium Plain Requires Adaptive Variety Which CanTolerate High Temperature And Drought Stress. The Main Of Objective Research Was To Find Out PotatoVariety Which Was Relatively More Adaptive To High Temperature In The Medium Plains. This Research WasConducted In Sibolangit District (680 Asl), Deli Serdang Regency, North Sumatera, Started From April UntilJuly 2016. Treatments Consisted Of 7 Potato Varieties Which Were Arranged In A Simple Randomized BlockDesign And Replicated Three Times. Results Showed That Plant Height Was Significantly Different AmongVarieties Evaluated, Whereas Greenness Intensity Of Leaves Seemed Homogeneous Among Varieties. SeveralMorphological Characters Of The Potato Including Leaf Area Index (LAI), Leaf Canopy Structure, LeafArrangement, Growth Habit, Stem Anthocyanin, A Frequency Of Flowering, And Color Of Flower Crown AreSignificantly Varied Depend On Crop Genotypes.
The Constitutional Accuracy of Legal Presumptions
Authors: Pandya Sachin S.
Published: September 2018

This paper is about a century-old yet durably-opaque constitutional doctrine that has the potential to disrupt every field of US law that uses legal presumptions. That doctrine demands, for any legal presumption, at least “some rational connection between the fact proved and the ultimate fact presumed.” The paper shows how that doctrine is best read to require likely-accurate presumptions, i.e., in the run of cases in which the presumption can apply, the probability of the presumed fact, given the proven fact, must provably exceed fifty percent. If so, however, lawyers and judges applying this doctrine face distinctive selection bias and reference class problems. The paper illustrates these and other issues with five examples: the McDonnell-Douglas presumption in employment discrimination law; the Bail Reform Act's presumption about a bail applicant's level of danger to others based on being charged with certain drug-sale crimes; the tort law doctrine of res ipsa loquitor; a presumed damages amount for emotional distress; and presumptions about whether a worker is an “employee” or “independent contractor.” In so doing, this paper contributes to the legal and philosophical literature on presumptions in adjudication, as well as ongoing controversies in the US law of tort, work, damages, and bail.
Ichthyosaurs from the French Rhaetian indicate a severe turnover across the Triassic–Jurassic boundary
Authors: Fischer Valentin , Capetta Henri , Vincent Peggy , Garcia Géraldine , Goolaerts Stijn , Martin Jérémy , Roggero Daniel , Valentin Xavier
Published: September 2018

Mesozoic marine reptiles went through a severe turnover near the end of the Triassic. Notably, an important extinction event affected ichthyosaurs, sweeping a large part of the group. This crisis is however obscured by an extremely poor fossil record and is regarded as protracted over the entire Norian–earliest Jurassic interval, for the lack of a more precise scenario. The iconic whale-sized shastasaurid ichthyosaurs are regarded as early victims of this turnover, disappearing by the middle Norian. Here we evaluate the pattern of this turnover among ichthyosaurs by analyzing the faunal record of two Rhaetian localities. One locality is Autun, eastern France; we re-discovered in this material the holotypes or partial ‘type’ series of Rachitrema pellati, Actiosaurus gaudryi, Ichthyosaurus rheticus, Ichthyosaurus carinatus, and Plesiosaurus bibractensis; a revised taxonomic scheme is proposed. The second assemblage comes from a new locality: Cuers, southeastern France. Both these assemblages provide several lines of evidence for the presence of shastasaurid-like ichthyosaurs in the Rhaetian of Europe. These occurrences suggest that both the demise of shastasaurids and the sudden radiation of neoichthyosaurians occurred within a short time window; this turnover appear more abrupt but also more complex than previously postulated and adds a new facet of the end-Triassic mass extinction.
The Impact of Adding A Self-Compassion Module To The Treatment of Opioid-Dependent Young Adults: A Pilot Study
Authors: Tomlin Kathyleen M. , Dykeman Cass
Published: September 2018

Young adult opioid addiction is on the rise in many parts of the country. Young adults’ use of opioids, in the form of illicit prescription drugs or heroin, is especially challenging for treatment engagement and retention due to high rates of relapse and debilitating shame and guilt. Normal developmental milestones of life are halted. Mental health research has found self-compassion training to be helpful; however, it is underrepresented in addiction research. Enhancing substance abuse best treatment practices such as motivational interviewing (MI) may result in fewer incidences of relapse, as well as a decrease in shame, depression, and anxiety when paired with a focus on self-compassion. The objective of this pilot study was to determine the feasibility and potential utility of large scale study examining whether adding a self-compassion module to treatment-as-usual (TAU) increases the frequency of client change talk compared with TAU alone. A secondary focus included a review of client satisfaction scores between the two study groups to determine how they would evaluate the treatment they received and their experiences participating in the study. There were 17 opioid-dependent young adults (ages 18–25) randomly assigned to one of two conditions in an outpatient substance abuse treatment clinic. Measurements of the frequency of change talk were collected at five distinct points during the intervention. At the completion of the final session, the participants evaluated their satisfaction scores using the CSQ-8 and responded to a series of open-ended questions. Results of an ANCOVA and independent t-tests were utilized to determine any differences between the two groups in the frequency of change talk and client satisfaction. An analysis of common themes shared by participants showed a preference for individual counseling and a structured place to go, as well as a desire for the intervention to be longer than three sessions. The study indicated that a focus on self-compassion combined with treatment-as-usual did not differ in outcome when compared with treatment-as-usual alone. Additionally, both treatment conditions were equal in terms of client satisfaction. However, it should be noted that pilot trials are highly susceptible to Type II error. Issues encountered in this pilot study that have implications for large scale efficacy studies on this topic and/or with young adult opioid users were discussed.
Williams syndrome, human self-domestication, and language evolution
Authors: Niego Amy , Benítez-Burraco Antonio
Published: September 2018

Language evolution resulted from changes in our biology, behavior, and culture. One source of these changes might be human self-domestication. Williams syndrome (WS) is a clinical condition with a clearly defined genetic basis and resulting in a distinctive behavioral and cognitive profile, including enhanced sociability. In this paper we show evidence that the WS phenotype can be satisfactorily construed as a hyper-domesticated human phenotype, plausibly resulting from the effect of the WS hemydeletion on several candidates for domestication and neural crest function. We also discuss the consequences of this link between domestication and WS for our current understanding of language evolution.
Does Compliance Pay? Social Standards and Firm-level Trade
Authors: Distelhorst Greg , Locke Richard M.
Published: September 2018

political economy, trade, labor, regulation, global supply chains
Biological Phenomena Mimic Astrophysical Principles Of Gravitation – Opening Perspective
Authors: Bhattacharjee Dr. Iresh Ranjan
Published: September 2018

It is conjectured that phenomena in biological microworld could be equated with astrophysical principles of gravitation. Fluids, gases that constitute 50-90 % of the total accredited biomass causes seclusion from stronger external gravitational fields. Seclusion due to buoyant condition is reflected in apparent ‘weight’ reduced. The g-value (self) to the tune of nanometer per second square in a massive body of a planet may be negligible, but in an isolated living mass at picometer distance, such acceleration is quite a significant force. Homogeneous and heterogeneous accretion; heating and cooling phenomena as well as the rhythmic pattern of growth due to elastic collisions in massive star; heat transfer mechanisms viz. radiation, (perspiration), conduction and convection; site of human core body temperature at liver, kidney, heart and parts of brain at central region under initial circular fetus situation; or coldest part of the periphery at toe, foot, hand demonstrates similarity between biological and astrophysical words
Investigating The Effect Of Textualization On Learning Vocabularies Among Iranian EFL Learners
Authors: Allahmoradi Nazal
Published: September 2018

Both first language (L1) learners and second language (L2) learners may incidentally gain knowledge of meaning through reading. While researchers tend to agree that incidental learning is responsible for the vast majority of L1 vocabulary learning, there is some suggestion that explicit learning of vocabulary may be responsible for most L2 vocabulary learning However, researchers agree that incidental vocabulary learning should be encouraged and incorporated into L2 learning. - There is no relationship between textualization and learning vocabulary among Iranian EFL learners.
Üniversite Öğrencilerinin Problem Çözme Becerileri ile Psikolojik Dayanıklılık Düzeylerinin Değerlendirilmesine Yönelik Bir Araştırma
Authors: Durmuş Mustafa , Okanlı Ayşe
Published: September 2018

Çalışma üniversite öğrencilerinin problem
çözme becerileri ile psikolojik dayanıklılıklarını etkileyen faktörlerin
incelenmesi amacıyla yapılmıştır. Araştırma, Muş il merkezinde bulunan Muş
Alparslan Üniversitesi’nde Mart -Şubat 2015 tarihleri arasında yürütülmüştür.
Araştırmanın evreninin Muş Alparslan Üniversitesi’nde tüm lisans bölümlerinin
1. ve 4. sınıfı olmak üzere 397 öğrenci oluşturmuştur. Veri toplamada
“Öğrencilerin sosyo- demografik özelliklerine ait sorular ”, “Yetişkinler İçin
Psikolojik Dayanıklılık Ölçeği” ve “Problem Çözme Envanteri” kullanılmıştır.
Araştırma için etik kurul onayı ve kurum izni alındıktan sonra sınıf ortamında
öğrencilere açıklamalar yapılarak gönüllülük esasına göre veriler toplanmıştır.
Verilerin değerlendirmesinde frekans ve yüzdelik hesaplama, verilerin dağılımı,
bağımsız gruplarda t testi, spearman koreleasyon analizi, çoklu regresyon
analizi ve tek yönlü varyans analizi testi kullanılmıştır. Öğrencilerin
psikolojik dayanıklılık puan ortalamalarının 98.52±17.78 olduğu belirlenmiştir.
Öğrencilerin problem çözme becerileri puan ortalamaları 102.72±21.85 olarak
bulunmuştur. Araştırma verilerinin değerlendirilmesi sonucunda; öğrencilerin
yaşları, anne eğitim durumları, okul yaşamında kendilerini başarılı bulma
durumları ve ailelerinin kendilerine karşı tutum değerlendirmeleri ile
psikolojik dayanıklılık puan ortalamaları arasındaki farkın istatistiksel
olarak anlamlı olduğu saptanmıştır(p<0.05). Ayrıca öğrencilerin yaşları,
anne eğitim durumları ve ailelerin gelir düzeyi ile problem çözme becerisi puan
ortalamaları arasındaki farkın istatistiksel olarak anlamlı olduğu
belirlenmiştir(p<0.05). Problem çözme becerileri puan ortalaması azaldıkça
psikolojik dayanıklılık puan ortalamasının arttığı tespit edilmiştir. Problem
çözme ile psikolojik dayanıklılık arasında anlamlı bir ilişki bulunmuştur
(p=0.000). Öğrencilerin psikolojik dayanıklılıkların orta düzeyde olduğu,  ekonomik durumun, anne eğitim durumunun, okul
yaşamının, aile tutumunun dayanıklılığı etkilediği, problem çözme becerilerinin
psikolojik dayanıklılığı etkilediği görülmüştür.
Yaşlı Bireylerde Yaşanılan Yer ile Yalnızlık Durumu Arasındaki İlişkinin Araştırılması
Authors: Saltan Asuman , Kalındemirtaş Küçük Mümine , Mert Boğa Selda
Published: September 2018

Çalışmanın amacı, ev ortamı ve huzur evinde yaşayan yaşlı bireylerde yalnızlık
durumunun incelenmesidir. Çalışmaya, Aralık-Şubat 2016
tarihleri arasında Yalova İli Çınarcık İlçesi’nde yaşayan 99 yaşlı birey
katıldı. Rastgele örneklem yöntemi kullanıldı. Araştırmacılar tarafından yaşlı
bireylerin zamanının geçirebileceği mekanlar (parklar, kahvehaneler, vb.)
ziyaret edildi. Çalışmamız tanımlayıcı niteliktedir. Çalışmada, bireylerin
yalnızlık durumunu değerlendirmede UCLA Yalnızlık Ölçeği (UCLA) kullanıldı.
Çalışma kapsamına alınan yaşlı bireylerin yaş ortalaması 74.96±8.12 bulunurken, bireylerin Vücut Kütle İndeksi (VKİ)
ortalaması 28.25±6.61 bulundu. UCLA ile yaş ve VKİ arasında istatistiksel olarak anlamlı ilişki
bulunmadı (p>0.05). UCLA ile yaşanılan yer ve cinsiyet
arasında yapılan analizde ise anlamlı farka rastlanmadı (p>0.05).
Literatüre göre yalnızlık yalnız yaşama ile ilişkili olabileceği gibi sosyal ve
emasyonel birçok faktörle ilişkili olabilmektedir. Çalışmamız ile yalnızlığa
etki edebilecek olan faktörlerden biri olan yaşanılan yer ile yalnızlık arasında
ki ilişki bulunmadı. Gelecekte örneklem büyüklüğü artırılarak yalnızlıkla
ilgili çalışmalara devam edilmesinin uygun olacağı görüşündeyiz.