bluuebunny/crossref_metadata_2025 huggingface dataset:
Expanding Opportunities for Systems Thinking, Conceptual Learning, and Participation through Embodied and Computational Modeling
Authors: Pierson Ashlyn E. , Brady Corey E.
Published: November 2020

Previous research has established that embodied modeling (role-playing agents in a system) can support learning about complexity. Separately, research has demonstrated that increasing the multimodal resources available to students can support sensemaking, particularly for students classified as English Learners. This study bridges these two bodies of research to consider how embodied models can strengthen an interconnected system of multimodal models created by a classroom. We explore how iteratively refining embodied modeling activities strengthened connections to other models, real-world phenomena, and multimodal representations. Through design-based research in a sixth grade classroom studying ecosystems, we refined embodied modeling activities initially conceived as supports for computational thinking and modeling. Across three iterative cycles, we illustrate how the conceptual and epistemic relationship between the computational and embodied model shifted, and we analyze how these shifts shaped opportunities for learning and participation by: (1) recognizing each student’s perspectives as critical for making sense of the model, (2) encouraging students to question and modify the “code” for the model, and (3) leveraging multimodal resources, including graphs, gestures, and student-generated language, for meaning-making. Through these shifts, the embodied model became a full-fledged component of the classroom’s model system and created more equitable opportunities for learning and participation.
Electrosprayed Nanoparticles Based on Hyaluronic Acid: Preparation and Characterization
Authors: Snetkov Petr , Zakharova Kseniia , Morozkina Svetlana , Baranov Mikhail , Olekhnovich Roman , Uspenskaya Mayya
Published: November 2020

Modern drug delivery systems demand the development of targeted polymer-carriers with the set of obligatory requirements. Thus, such capsules must have total biocompatibility, biodegradability, and possess non-allergenic, and non-tumorigenic properties. Hyaluronic acid (HA), as a natural linear polysaccharide that is included in the pericellular and extracellular matrixes, satisfies all these demands in the best possible way. In this study, the biopolymer nanoparticles with an average diameter of 300 nm were successfully obtained from aqueous HA solutions by electrospraying technique and characterized. Due to the presence of active functional groups in the structure of HA, such polymer particles can incorporate various pharmaceutical agents. This finding expands the investigation and subsequent application of drug-loaded nanoparticles based on HA as challenging and advanced targeted delivery systems.
The 25 kDa HCN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity
Authors: Deppe Julian , Weisemann Jasmin , Mahrhold Stefan , Rummel Andreas
Published: November 2020

The extraordinarily potent clostridial neurotoxins (CNTs) comprise tetanus neurotoxin (TeNT) and the seven established botulinum neurotoxin serotypes (BoNT/A-G). They are composed of four structurally independent domains: the roles of the catalytically active light chain, the translocation domain HN, and the C-terminal receptor binding domain HCC are largely resolved, but that of the HCN domain sandwiched between HN and HCC has remained unclear. Here, mutants of BoNT/A, BoNT/B, and TeNT were generated by deleting their HCN domains or swapping HCN domains between each other. Both deletion and replacement of TeNT HCN domain by HCNA and HCNB reduced the biological activity similarly, by ~95%, whereas BoNT/A and B deletion mutants displayed >500-fold reduced activity in the mouse phrenic nerve hemidiaphragm assay. Swapping HCN domains between BoNT/A and B hardly impaired their biological activity, but substitution with HCNT did. Binding assays revealed that in the absence of HCN, not all receptor binding sites are equally well accessible. In conclusion, the presence of HCN is vital for CNTs to exert their neurotoxicity. Although structurally similar, the HCN domain of TeNT cannot equally substitute those of BoNT and vice versa, leaving the possibility that HCNT plays a different role in the intoxication mechanism of TeNT.
Rumen and Serum Metabolomes in Response to Endophyte-Infected Tall Fescue Seed and Isoflavone Supplementation in Beef Steers
Authors: Ault-Seay Taylor B. , Melchior-Tiffany Emily A. , Clemmons Brooke A. , Cordero Juan F. , Bates Gary E. , Flythe Michael D. , Klotz James L. , Ji Huihua , Goodman Jack P. , McLean Kyle J. , Myer Phillip R.
Published: November 2020

Fescue toxicosis impacts beef cattle production via reductions in weight gain and muscle development. Isoflavone supplementation has displayed potential for mitigating these effects. The objective of the current study was to evaluate isoflavone supplementation with fescue seed consumption on rumen and serum metabolomes. Angus steers (n = 36) were allocated randomly in a 2 × 2 factorial arrangement of treatments including endophyte-infected (E+) or endophyte-free (E−) tall fescue seed, with (P+) or without (P−) isoflavones. Steers were provided a basal diet with fescue seed for 21 days, while isoflavones were orally administered daily. Following the trial, blood and rumen fluid were collected for metabolite analysis. Metabolites were extracted and then analyzed by UPLC-MS. The MAVEN program was implemented to identify metabolites for MetaboAnalyst 4.0 and SAS 9.4 statistical analysis. Seven differentially abundant metabolites were identified in serum by isoflavone treatment, and eleven metabolites in the rumen due to seed type (p < 0.05). Pathways affected by treatments were related to amino acid and nucleic acid metabolism in both rumen fluid and serum (p < 0.05). Therefore, metabolism was altered by fescue seed in the rumen; however, isoflavones altered metabolism systemically to potentially mitigate detrimental effects of seed and improve animal performance.
Application of Next Generation Sequencing (NGS) in Phage Displayed Peptide Selection to Support the Identification of Arsenic-Binding Motifs
Authors: Braun Robert , Schönberger Nora , Vinke Svenja , Lederer Franziska , Kalinowski Jörn , Pollmann Katrin
Published: November 2020

Next generation sequencing (NGS) in combination with phage surface display (PSD) are powerful tools in the newly equipped molecular biology toolbox for the identification of specific target binding biomolecules. Application of PSD led to the discovery of manifold ligands in clinical and material research. However, limitations of traditional phage display hinder the identification process. Growth-based library biases and target-unrelated peptides often result in the dominance of parasitic sequences and the collapse of library diversity. This study describes the effective enrichment of specific peptide motifs potentially binding to arsenic as proof-of-concept using the combination of PSD and NGS. Arsenic is an environmental toxin, which is applied in various semiconductors as gallium arsenide and selective recovery of this element is crucial for recycling and remediation. The development of biomolecules as specific arsenic-binding sorbents is a new approach for its recovery. Usage of NGS for all biopanning fractions allowed for evaluation of motif enrichment, in-depth insight into the selection process and the discrimination of biopanning artefacts, e.g., the amplification-induced library-wide reduction in hydrophobic amino acid proportion. Application of bioinformatics tools led to the identification of an SxHS and a carboxy-terminal QxQ motif, which are potentially involved in the binding of arsenic. To the best of our knowledge, this is the first report of PSD combined with NGS of all relevant biopanning fractions.
Bedload Velocity and Backscattering Strength from Mobile Sediment Bed: A Laboratory Investigation Comparing Bistatic Versus Monostatic Acoustic Configuration
Authors: Conevski Slaven , Aleixo Rui , Guerrero Massimo , Ruther Nils
Published: November 2020

Despite the many advantages of using active ultrasound sonars, recent studies have shown that the specific acoustic geometry, signal-processing configuration, and complex surface-volume scattering process at the riverbed introduce several uncertainties in bedload estimation. This study presents a comparison of bedload velocity and bottom echo intensity measurements performed by monostatic and bistatic active ultrasound systems. The monostatic configuration is widely applied in the field to measure the apparent velocity at the riverbed with an acoustic current Doppler profiler (ADCP). Two laboratory investigations were conducted in two different hydraulic facilities deploying ADCP Stream Pro, monostatic and bistatic acoustic velocity profilers, manufactured by Ubertone. The bistatic instruments provided more accurate bedload velocity measurements and helped in understanding the acoustic sampling of the monastic systems. The bistatic profiles succeeded in measuring a profile over the active bedload layer, and the monostatic instruments resulted in different bedload velocity estimations depending on the acoustic resolution and sampling. The echo intensity increased in the cells measured within the active bedload layer with respect to the cell measuring the water column above. The cells that sampled the immobile bed surface beneath the bedload layer showed a reduction of the echo intensity compared with the cells above. The acoustic sampling, which combines the measurement volume geometry and internal processing, seems crucial for more accurate outputs. Future research about the use of monostatic instruments in the field should aim to define the best possible setting for the acoustic parameters at a given bedload condition that may be tuned by evaluating the backscattering at the river bottom together with the apparent bedload velocity.
Impact of Land Cover Change Due to Armed Conflicts on Soil Erosion in the Basin of the Northern Al-Kabeer River in Syria Using the RUSLE Model
Authors: Almohamad Hussein
Published: November 2020

Due to armed conflicts, the sudden changes in land cover are among the most drastic and recurring shocks on an international scale, and thus, have become a major source of threat to soil and water conservation. Throughout this analysis, the impact of land cover change on spatio-temporal variations of soil erosion from 2009/2010 to 2018/2019 was investigated using the Revised Universal Soil Loss Equation (RUSLE) model. The goal was to identify the characteristics and variations of soil erosion under armed conflicts in the basin of the Northern Al-Kabeer river in Syria. The soil erosion rate is 4 t ha−1 year−1 with a standard deviation of 6.4 t ha−1 year−1. In addition, the spatial distribution of erosion classes was estimated. Only about 10.1% of the basin is subject to a tolerable soil erosion rate and 79.9% of the study area experienced erosion at different levels. The soil erosion area of regions with no changes was 10%. The results revealed an increase in soil erosion until 2013/2014 and a decrease during the period from 20013/2014 to 2018/2019. This increase is a result of forest fires under armed conflict, particularly toward the steeper slopes. Coniferous forest as well as transitional woodland and scrub are the dominant land cover types in the upper part of the basin, for which the average post-fire soil loss rates (caused by factor C) were 200% to 800% higher than in the pre-fire situation. In the period from 2013/2014 to 2019/2020, soil erosion was mitigated due to a ceasefire that was agreed upon after 2016, resulting in decreased human pressures on soils in contested areas. By comparing 2009/2010 (before war) with 2018/2019 (at the end of the war stage), it can be concluded that the change in C factors slowed down the deterioration trend of soil erosion and reduced the average soil erosion rate in more than half of the basin by about 10–75%. The area concerned is located in the western part of the basin and is relatively far from the centers of armed conflicts. In contrast, the areas with increased soil erosion by about 60–400% are situated in the northeast and east, with shorter distances to armed conflict centers. These findings can be explained by forest fires, after which the burned forests were turned into agricultural land or refugee camps and road areas. Understanding the complex biophysical and socio-economic interactions of exposure to land loss is a key to guarantee regional environmental protection and to conserve the ecological quality of soil and forest systems.
Seasonal Distributions of Phytoplankton and Environmental Factors Generate Algal Blooms in the Taehwa River, South Korea
Authors: Sim Bo-Ram , Kim Hyung-Chul , Kim Chung-Sook , Kim Jin-Ho , Park Kyung-Woo , Lim Weol-Ae , Lee Won-Chan
Published: November 2020

Algal blooms have occurred in the Taehwa River estuary in South Korea despite the improvement of water quality since environmental renewal projects in the 1990s. In this study, we investigated the causes of algal blooms by measuring the water retention time using a floating buoy, water quality parameters, and phytoplankton distribution data from 2012. An algal bloom did not occur in February because of phosphate limitations in the Taehwa River estuary; however, the concentration of nutrients in the water inflow from the basin triggered a significant algal bloom in the upper estuary in the month of May. In this regard, the phytoplankton population was dominated by nano- and pico-sized flagellates. In August, the freshwater inflow into the estuary greatly increased due to heavy rainfall, resulting in a shorter retention time of the water bodies, which seemed to prevent an algal bloom. In November, a bloom of Cryptophyceae occurred at one of the sites (the U2 site) due to sufficient nutrients in the water and the long retention times of the water bodies. Our results indicate that a decrease in the nutrients (N and P) supplied from the basin is required for a reduction in algal blooms in the Taehwa River estuary. Additional studies are needed to further elucidate the effects of the land-based, nutrient-rich pollutants flowing into the Taehwa River estuary on algal bloom generation considering the fact that the streams have different environmental characteristics.
Mycobiota of Konya mold-ripened (Kuflu) Tulum cheese and the diversity of Penicillium roqueforti isolates
Authors: SERİ Meryem , METİN Banu
Published: November 2020

Konya Kuflu Tulum cheese is a well-known variety of Turkish mold-ripened cheeses produced by cutting the mature Tulum cheese into pieces to allow the filamentous fungi to grow on its surface in the cool and humid atmosphere in cellars or caves. The aim of the present study was to determine the fungal flora of Kuflu cheese using 54 filamentous fungi and 8 yeasts that were isolated from 26 cheese samples. Internal transcribed spacer (ITS) sequencing indicated that 53 of the mold isolates were Penicillium roqueforti and 1 was Cladosporium cladosporioides. The yeasts were identified as Pichia membranifaciens, Candida zeylanoides, Debaryomyces hansenii, and Geotrichum candidum. Morphological examination of the P. roqueforti isolates on various media revealed similar phenotypes among all but two isolates; however, (GTG)5 fingerprinting analysis indicated that the isolated P. roqueforti strains were highly similar in all but one case, which displayed a different pattern. To our knowledge, this study represents the first to conduct molecular methods for identification of fungi associated with Konya Kuflu Tulum cheese. In addition, the morphological and genetic diversities of the Turkey-originated P. roqueforti isolates are presented.
Corrosion Inhibition of Cu-Zn-Fe Alloy in Hydrochloric Acid Medium by Crude Ethanol Extracts from Roots-Leaves Synergy of Solanum melongena
Authors: Ugi Benedict U.
Published: November 2020

The corrosion inhibition of Cu-Zn-Fe alloy in hydrochloric acid medium by crude ethanol extracts from roots-leaves synergy of Solanum melongena have been studied with chemical methods (mass loss and gasometric methods). At 3.0 grams per litre concentration of the roots-leaves synergy of Solanum melongena, it was observed that a 98.8 % inhibition efficiency was recorded as corrosion rate of alloy was decreasing with inhibitor increase. Temperature evaluation on the inhibitor showed 99.2 > 88.4 > 85.6 % as trial was conducted from 303-323 respectively, and in respect to increasing concentration, corrosion rate was found to be 1.718 > 0.013, 0.0192 and 0.247 at 303, 313 and 323 respectively. All these present a good result for the synergistic inhibitor and a proof of its efficiency in controlling the corrosion of Cu-Zn-Fe alloy in hydrochloric acid medium. Inhibition mechanism was deduced from the activation and thermodynamic parameters that govern the process. Adsorption of extract on the Cu-Zn-Fe alloy was found to obey the Langmuir adsorption isotherm. The phenomenon of physical adsorption is proposed from the obtained thermodynamic parameters.
Individual Human Life Morality of Vethathiri Maharishi
Authors: D Sivanantham
Published: November 2020

From the beginning of the Human race to the present day there has been need to guide the lives of huaman beings. The main reason for this is that man suffers from material attraction  and perceptual giddiness. So in every age Scholars, Sages, and Saints have appeared and guided human life to be better and happier. Vethathiri Maharishi, the great philosopher who emerged in the twentieth century in that way  and led man to move in the state of knowledge and to live in peace and pleasure. Vethathri Maharishi has given lot of books to the Tamil literature world based on the lofty idea that world peace created through individual human peace. Among them the Gnanak kalanjiyam is a notable book which Published in two volumes, the book contains 1854 songs. This  article examines the virtues mentioned  by vethathiri maharishi  under the rhetoric of virtue in his book as  the  main virtues that every individual man should follow in his life as the development Gnanak kalanjiyam of the individual who is the foundation  of the society as the cause of social and  national development.
Enseñanza religiosa y educación laica en las escuelas públicas de Argentina (1884 a 2015)
Authors: Rodríguez Laura Graciela
Published: November 2020

En este artículo analizamos uno de los múltiples aspectos de la religiosidad o la laicidad, como son la dimensión jurídica y la inclusión de la enseñanza religiosa o la educación laica en las Constituciones Provinciales, Leyes y Decretos nacionales y provinciales de educación. En este trabajo buscamos efectuar un estudio de largo plazo que permita identificar los cambios y continuidades en relación a la enseñanza religiosa o la educación laica en las escuelas públicas estatales de nivel primario, tanto a nivel nacional como dentro de una misma provincia, desde 1884 hasta 2015.
Richard Blackmore y su tratado sobre el spleen inglés
Authors: Gattinoni Andrés
Published: November 2020

En 1725, el poeta y médico inglés sir Richard Blackmore publicó A Treatise of the Spleen and Vapours. Esta obra estaba dedicada a lo que el autor denominaba el “spleen inglés”, un trastorno físico y mental, históricamente asociado con la melancolía que, según él, dominaba de manera universal y tiránica sobre los hombres y las mujeres de Inglaterra. Este artículo ofrece una edición crítica del prefacio del tratado de Blackmore. En la introducción, se presenta una semblanza del médico y se contextualiza el documento inscribiéndolo en dos debates de principios del siglo XVIII en los que participó sir Richard: la Querella entre los Antiguos y los Modernos y una polémica poco conocida acerca de la función fisiológica del bazo.
Las prácticas electorales coloniales y la conformación de un habitus electoral. El Cabildo de la Villa de Luján entre 1771 y 1821
Authors: Galimberti Vicente Agustín
Published: November 2020

Este artículo examina los procesos electorales desarrollados durante las últimas décadas del período colonial en la jurisdicción del Cabildo de la Villa de Luján. El objetivo del mismo consiste en analizar la posible existencia de tradiciones y prácticas electorales coloniales que pudieron haber informado y orientado a los actores frente a los cambios que trajo en las elecciones la adopción del principio de la soberanía popular durante de la revolución. Analizamos la vida política local, considerando a los habitantes y los pueblos rurales como sujetos activos en la construcción tanto de una tradición electoral como en los cambios que se desarrollaron en ella durante las primeras décadas del siglo XIX.
La Sierra de Santiago y el Valle de Catamarca (Gobernación del Tucumán) a principios del siglo XVII: reflexionando sobre una nueva regionalización
Authors: Castro Olañeta Isabel , Carmignani Leticia
Published: November 2020

Presentamos el análisis de un informe fechado en febrero de 1607, resultado de la Visita al Partido de la Sierra –dependiente y parte de la jurisdicción de la ciudad de Santiago del Estero–, que fue realizada por el Teniente de Naturales Francisco de Betanzos quien, por orden del Gobernador del Tucumán Alonso de Ribera, recorrió la tierra aplicando las Ordenanzas de Abreu y desagraviando a los indios. La visita incluye información sobre el valle de Catamarca y la ladera oriental del cordón Ancasti y Alto-Gracián, las sociedades indígenas y el funcionamiento de las encomiendas. Su análisis nos permite proponer una nueva regionalización para la Gobernación del Tucumán y una posible complementariedad económica entre sus distintos espacios aprovechada por los encomenderos en el período temprano colonial.
EUJANIAN, Alejandro El pasado en el péndulo de la política. Rosas, la provincia y la nación en el debate político de Buenos Aires, 1852-1861, Universidad Nacional de Quilmes Editorial, Bernal, 2015, 308 pp. ISBN 978-987-558-369-6.
Authors: Zubizarreta Ignacio
Published: November 2020

Si bien algunos estudios históricos comienzan a relativizar la eficacia explicativa de las periodizaciones “clásicas” de nuestro pasado, la caída del régimen de Juan Manuel de Rosas, sin dudas, representa un verdadero parteaguas; un mojón inevitable que nos indica un momento de profunda ruptura entre los eslabones que unen el paso del tiempo. Las consecuencias inmediatas de la batalla de Caseros (1852) no han sido fecundamente estudiadas, al menos desde que el campo historiográfico fue renovado y profesionalizado en la década de 1980. Y eso, en parte, porque el periodo en cuestión se enmarca en un contexto inaprensible: la secesión de Buenos Aires del resto de las provincias confederadas derivó en una evidente complejidad para lograr un análisis que lograra trascender miradas particulares sobre el fenómeno.
Ciudadanos y soldados en el debate de la Ley sobre el Servicio Militar Voluntario en la Argentina democrática
Authors: Soprano Germán
Published: November 2020

Este artículo tiene por objeto las concepciones de ciudadano y soldado presentadas en el debate parlamentario sobre la Ley de Servicio Militar Voluntario. Comprende: 1) los proyectos que contribuyeron a la elaboración de un amplio consenso parlamentario; 2) el reconocimiento de demandas de los ciudadanos contra el servicio militar obligatorio; 3) las comparaciones entre los proyectos de ley de servicio militar de 1901 y 1994; 4) la influencia de la experiencia del terrorismo de Estado en la última dictadura en el resguardo de los derechos humanos del soldado; 5) y la definición de los ciudadanos que pueden ser soldados voluntarios y aquellos exceptuados de la conscripción en circunstancias excepcionales.
Reseña de: CÓRDOBA, Lorena; BOSSERT, Federico y RICHARD, Nicolás (editores) Capitalismo en las selvas: Enclaves industriales en el Chaco y Amazonía indígenas (1850-1950), Ediciones del Desierto, San Pedro de Atacama, 2015, 316 pp. ISBN 978-956-9693-02-1.
Authors: Chávez Matías Rodrigo
Published: November 2020

Este libro analiza los principales enclaves sostenidos por fuerza de trabajo indígena en el Chaco y la Amazonía entre los años 1850 y 1950, período en que se produjo la colonización interna de esos espacios a partir de la penetración del capitalismo extractivo que reestructuró las relaciones sociales y redefinió el ordenamiento territorial. Se trata de una compilación que reúne doce capítulos heterogéneos escritos por dieciséis especialistas procedentes de seis países diferentes, los cuales ofrecen estudios de caso que mediante diferentes perspectivas problematizan un proceso de cambios vertiginosos.
El factor Rosas. Juan Manuel de Rosas. La construcción de un liderazgo político de Raúl O. Fradkin y Jorge Gelman
Authors: Hora Roy
Published: November 2020

Este texto analiza la biografía de Juan Manuel de Rosas escrita por Raúl O. Fradkin y Jorge Gelman. El trabajo sitúa esta biografía en relación con estudios anteriores y analiza sus principales contribuciones. Finalmente, discute las ventajas y limitaciones del modo en que los autores enfocan el problema de la relación entre Rosas como líder político y el contexto en el que desarrolló su carrera.
Supervivencia y serendipity en la literatura argentina
Authors: Burucúa José Emilio
Published: November 2020

El siguiente texto ofrece un recorrido por obras icónicas de la literatura argentina teniendo como ilación el concepto de serendipity. El Facundo de Sarmiento, “La muerte y la brújula” de Borges, “La trama celeste” de Bioy Casares, Respiración artificial de Piglia son analizados desde esta perspectiva en que algo se encuentra, precisamente, cuando se busca otra cosa.
CARBOXYMETHYLATION OF POLYSACCHARIDES – A COMPARATIVE STUDY
Authors: LARS GABRIEL , TIED ANTJE , HEINZE THOMAS
Published: November 2020

The present study describes the heterogeneous carboxymethylation of xylan,α-1,3-glucan, glucomannan, pullulan, curdlan, galactoglucomannan, and agarose with sodium monochloracetate (SMCA) using iso-propanol as slurry medium in the presence of caustic soda. Using heteropolysaccharides for the carboxymethylation, higher DS values are
obtained compared to the DS of homopolysaccharides. The influence of the amount caustic soda in the reaction medium is studied. The characterization of the products obtained is performed by means of 13C-NMR spectroscopy. Carboxymethylation transforms the investigated polysaccharides into water-soluble products.
Sey Yew Romanê Verênî Kilama Pepûgî Ser O Analîzêk
Authors: YILDIZ Pınar
Published: November 2020

Na xebate de ma hewl da ke romanê yewin yê kirmanckî (zazakî) Kilama Pepûgî (2000) ser o analîzêk bikê. Na xebate destpêk û hîrê beşan ser o awan bîya. Destpêk de ma tarîxê vejîyayîşê romanî ser o vindertî û edebîyatê rojhelatî de bîlhesa edebîyatê kurdkî de romanî senîn dest pêkerdo, ser o vindertî. Rolê modernîzm û neteweperwerî romanî ser o esto. Coka beşê yewinî de ma tesîrê modernîzmî, neteweperwerî û folklorî yo ke romanî ser o esto ra ewnîyayî. Bîlhesa ma waşt bimojnê ra ke nê mefhuman nê romanê verênî ser o senîn tesîr kerdo. Seba ke Kilama Pepûgî, romanêko tarîxî yo ma beşê dîyinî de zî mefhûmê romanê tarîxî ser o vindertî û ma hewl da ke nê romanî zî sey yew romanê tarîxî analiz bikê. Beşê peyênî de zî ma no roman hetê unsuranê romanî ra analiz kerd. Çike zafê romanê verênî hetê unsuranê teknîkan ra wayîrê probleman ê û kalîteyêkê edebî ra dûrî yê. Ma waşt bimojnê ra ke Kilama Pepûgî de nê unsurê teknîkî senîn ameyê karardiş. Seba ke Kilama Pepûgî hem romanê yew dewrî yo hem zî romano yewin o ma analîz û rexneyê xo goreyê şert û mercê ê dewrî û tarîxê çapbîyayîşê romanî kerdî. Yanî perspektîfê ma ser o tesîrê têkilîya nuştox-eser-dewr bi. Seba ke ma waşt fikrêk bidî wendoxan ma peynîye de yew bîblîyografîya romananê kirmanckî îlawe kerdî. Yanî mabênê vîst serran de romanî ke bi kirmanckî nusîyayê û açarnîyayî, ma listeya inan îlaweyê na xebate kerdî.
Experimental study on the strength of silty soft soil in beach with polypropylene fiber reinforcement
Authors: Daozheng Qi , Cong Gu , Jiajia Fu , Yao Wang
Published: November 2020

The effects of polypropylene fiber reinforcement on shear strength and unconfined compressive strength of
silty soft soil in tidal flats were studied. Through shear test and unconfined compression test, Experimental study was
conducted on silty soft soil of allene fiber reinforced beach with 0~0.6% different mass content and 3 ~18m different
length. The failure process and mechanism of fiber reinforced soil samples were also discussed. The test results show
that: Shear strength (cohesion and internal friction Angle) and unconfined compressive strength increased rapidly in the
early stage with the increase of fiber content, and gradually decreased after reaching the peak at a certain content. In
this test, the optimal fiber length corresponding to shear strength is 9mm. When the content is less than 0.6%, the optimal content of cohesion is about 0.2%, and the optimal content corresponding to the Angle of internal friction is between 0.2% and 0.3%. Within the range of 18mm fiber length in the experimental study, unconfined compressive
strength increased with the increase of fiber length, and the optimal fiber content corresponding to unconfined compressive strength was 0.2%. The main effects of polypropylene fiber reinforcement on soil cohesion and unconfined compressive strength are not obvious.
UJI AKTIVITAS ANTIOKSIDAN FRAKSI N-HEKSAN DAUN AFRIKA (Vernonia amygdalina Del.) DENGAN METODE DPPH
Authors:   Sekolah Tinggi Ilmu Kesehatan Samarinda, Fatimah Nurul , Sundu Reksi
Published: November 2020

Free radicals and reactive species are widely believed to contribute to the development of several diseases by causing oxidative stress and eventually oxidative. Vernonia amygdalina (Astereacea) is a small shrub or tree between 1 and 5m high growing throughout tropical Africa. Plants are generally known as bitter leaves is well cultivated and is a general market for merchandise in several countries. The purpose of this study was to determine the antioxidant activity of hexane fraction from ethanol extract od Frican leaves (Vernonia amygdalina Del.). The method used in this study was the DPPH (1,1-Diphenil-2-Picrylhydrazyl) method. The result of phytochemical screening showed that ethanolic extract of African leaves contained a composition of secondary metabolites of alkaloids, flavonoids, tannins, steroids/triterpenoids and saponins. The antioxidant activity of the extract of n-hexane fraction was classified as very weak with an IC50 value of 317.98 ppm.
PENILAIAN DATA AWAL PENERAPAN BRIEF CONSELING FARMASIS DALAM PENINGKATAN PERILAKU, KEPATUHAN MINUM OBAT, HASIL TERAPI DAN KUALITAS HIDUP PASIEN HIPERTENSI DI RSUD ULIN BANJARMASIN
Authors:   Akademi Farmasi ISFI Banjarmasin, Aryzki Saftia , Wahyuni Amaliyah
Published: November 2020

Hypertension is one of the deadliest diseases in the world. As many as 1 billion people in the world or 1 in 4 adults suffer from this disease.In fact, it is estimated that the number of hypertension sufferers will increase to 1.6 billion by 2025. Based on data from Basic Health Research (Riskesdas) in 2018, the prevalence of hypertension is based on measurement results for people aged ≥ 18 years in South Kalimantan, ranking number 1 in Indonesia. This result increased from the data in 2013 the prevalence of hypertension was 30.4% to 44.1%. Patient behavior by controlling the patient's blood pressure will improve the patient's quality of life. The purpose of this study was to assess the initial data on the application of the effect of pharmacist brief counseling in improving behavior, medication adherence, therapy outcomes and quality of life for hypertensive patients at Ulin Banjarmasin Hospital. The study was a quasi-experimental study using two groups with prospective patient data collection with inclusion and exclusion criteria. The exclusion criteria were pregnant, deaf and absent patients at the second visit. Data collection comes from medical records and is carried out by interviewing then filling out a questionnaire. Data were analyzed using SPSS Version 16. The results of the study were on cognitive (0.408), affective (0.000), psychomotor (0.240) patient behavior; compliance (0.096); quality of life (0,000); Systolic BP (0.588) and Diastolic BP (0.626).
UJI AKTIVITAS ANALGETIK EKSTRAK ETANOL HERBA SEMBUKAN (Paederia foetida L.) PADA MENCIT PUTIH JANTAN (Mus musculus) YANG DIINDUKSI DENGAN ASAM ASETAT
Authors:   Sekolah Tinggi Ilmu Kesehatan Samarinda, Sentat Triswanto , Handayani Fitri , Indraswari Ellen
Published: November 2020

Sembukan plants (Paederia foetida L.) are wild vines that are usually used by people as potential medicinal plants for pain. The purpose of this study was to determine the ethanol extract of sembukan’s herbal analgesic activity in male white mice (Mus musculus) and determine the optimal dose of the ethanol extract from sembukan’s herbal (Paederia foetida L.) which has the potential as an analgesic. Sembukan’s herbal is extracted with 70% ethanol solvent and an analgesic activity test is divided into 5 treatment groups namely positive control group (potassium diclofenac), negative control, dose I (80 mg / kg body weight), dose II (160 mg / kg body weight) ) and dose III (320 mg / kg body weight) by oral administration. Thirty minutes after administration, the mice were given an indicator of pain, 0.5% acetic acid. Analgesic power is calculated by counting the amount of stretching of mice for 1 hour. From the results of the study, the ethanol extract of sembukan’s herbal has analgesic activity in male white mice with percent dose analgesic power 35.18%, dose II 53.58% and dose III 68.98%. The optimal dose that has potential as an analgesic in male white mice is dose III with 68.98% analgesic power.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK GANGGANG HIJAU (Ulva lactuca L.) DENGAN VARIASI KONSENTRASI PELARUT ETANOL 60%, 75%, DAN 96% MENGGUNAKAN METODE DPPH (1,1-difenil-2-pikrilhidrazil)
Authors:   Universitas Ahmad Dahlan, Kameliani Desti , Salamah Nina , Guntarti Any
Published: November 2020

Free radicals give a negative effect. According to earlier research, Spyrogyra and Ulva lactuca L. have an anti-oxidant activity. This research aim to knowing the extract potential of green algae (Ulva lactuca) with variety concentration solvent as anti-oxidant by DPPH method, and finding the price of IC50 ethanol extract which compared with Galat acid. Extraction technic was maseration with ethanol solvent 60%,75%, and 96% which is implemented a qualitative test of extract active compound of U. lactuca Antioxidant activity of U. lactuca extract measured with spektrofotometri by using DPPH (1,1-difenil-2-pikrilhidrazil) method to get percentation of free radical resistor. The analytical result using SPSS, statistically got 95% credibility (p=0,05). This research showed that activity of antioxidant ethanol extract 96% of U. lactuca was higher than ethanol extract 60% and 75%. Activity of antioxidant ethanol extract 60%,75%, and 96% which confirmed by value of IC50 continously are 441,70 mg/ml ; 242,10 mg/ml dan 2,04 mg/ml. Whereas the value of IC50 galat acid standard is 3,92 x 10-3mg/ml. Based on tests of conducted antioxidant activity, the gallic acid has a strong antioxidant power, U. lactuca have a very weak antioxidant power
Gambaran audiogram pada anak dengan penyakit ginjal kronis yang menjalani hemodialisis
Authors: Muyassaroh Muyassaroh , Muryawan Heru , Cahyani Nastiti Dwi
Published: November 2020

Latar belakang: Penyakit ginjal kronis (PGK) adalah kerusakan ginjal atau penurunan laju filtrasi glomerulus (GFR) kurang dari 60 mL / min / 1,73 m2 paling sedikit 3 bulan. Pasien PGK memiliki resiko kejadian kurang pendengaran yang tinggi. Tujuan: Mengetahui gambaran audiogram anak dengan PGK yang menjalani hemodialisis. Metode : Diskriptif retrospektif  7 kasus PGK ada anak yang menjalani hemodialisis di RSUP Dr.Kariadi Semarang Juli 2017. Hasil : didapatkan 5 kasus(71,4%) kurang pendengaran sensorineural, 1 kasus (14,3%) kurang pendengaran campuran (MHL) dan 1 kasus (14,3%) normal. Derajat kurang pendengaran bervariasi dari derajat ringan sampai sangat berat. Kesimpulan: Kurang pendengaran sensorineural sebagian besar terjadi pada anak dengan PGK yang menjalani hemodialisis.

Kata kunci : Audiogram, SNHL, PGK

 

Background: Chronic kidney disease (CKD) is kidney damage or a decrease in glomerular filtration rate (GFR) of less than 60 mL / min / 1.73 m2 for at least 3 months. Patients with CKD have a high risk of hearing loss. Objective: The aim of illustrate the audiogram on  children with chronic kidney disease undergoing hemodialysis. Methode : Descriptif retrospective to seven cases of children with chronic kidney disease who undergoing hemodialysis in Karyadi hospital juli 2017. Result : Five cases (71,4%) with sensorineural hearing loss. One case(14,3%) showed severe mix hearing loss, one cases(14,3%)  with normal audiogram. The degree of hearing loss  from mild to profound Conclusion: Sensorineural hearing loss may occur in the majority of children with CKD on hemodialysis  

Keywords : Audiogram, SNHL, PGK
Kasus Dua Orang Wanita Umur 36 Tahun Dan 60 Tahun Dengan Akromegali
Authors: Ismayanti Fajri , Sukmaningtyas Hermina
Published: November 2020

Kasus Akromegali di RSUP dr. Kariadi sangat jarang terdeteksi pada fase awal karena minimnya gejala yang ditimbulkan. Pasien ditemukan tanpa sengaja biasanya datang dengan keluhan penyerta yang lain. Pemeriksaan Radiologi membantu menegakkan diagnosis Akromegali.

Dilaporkan 2 kasus wanita usia 36 tahun dan 60 tahun dengan Akromegali. Kasus pertama Ny. D usia 36 tahun dengan keluhan benjolan di leher dan sulit menelan datang ke poliklinik Penyakit Dalam RSUP dr. Kariadi. Pada pemeriksaan USG colli didapatkan pembesaran kelenjar tiroid, penebalan isthmus, nodul solid dengan jaringan nekrotik (ukuran terbesar ± 3.64 x 2.16 cm). Kasus kedua, Ny. N usia 60 tahun dengan keluhan nyeri diseluruh sendi. Tulang membesar, mentruasi berhenti pada usia 35 tahun. Pada pemeriksaan radiologi X Foto vertebra lumbosacral tampak gambaran Ankylosing Spondilosis. Pada pemeriksan MRI kepala kedua pasien diatas ditemukan makroadenoma. Kedua pasien berperawakan pendek dengan pembesaran tangan, kaki dan tulang wajah (prognatism)

Akromegali adalah suatu penyakit akibat dari peningkatan sekresi hormon pertumbuhan (somatotropin) oleh sel eosinofilik dari lobus anterior kelenjar pituitari, yang disebabkan oleh hiperplasia kelenjar atau tumor yang menyebabkan pertumbuhan tulang yang meningkat. Akromegali umum ditandai dengan pembesaran tangan, kaki dan tulang wajah.

Akromegali menyebabkan perubahan bertahap pada bentuk wajah, seperti rahang bawah dan alis yang menonjol, hidung membesar, bibir menebal dan gigi jarang. Akromegali cenderung berkembang perlahan. Pemeriksaan foto cranium, tangan dan kaki menunjukkan kelainan pada tulang.

Dilaporkan kasus diatas untuk membantu klinisi menegakkan diagnosa Akromegali dengan menggunakan multi modalitas radiografi, sehingga dapat ditegakkan lebih awal untuk  membantu tatalaksana pasien.

KATA KUNCI : Akromegali, Prognatism, Makroadenoma
A IMPORTÂNCIA DA CONTABILIDADE PARA OS PEQUENOS PRODUTORES: UM ESTUDO DE CASO NA FEIRA AGROUFAM
Authors: Moreira Silva Elaine , Silva Rissia Ribeiro da
Published: November 2020

A contabilidade é uma ferramenta fundamental para a gestão de qualquer negócio, presente tanto nas grandes empresas como nos pequenos empreendimentos. Este trabalho tem como objetivo verificar a presença das Ciências Contábeis entre os participantes da feira denominada Agroufam, que ocorre dentro do campus da Universidade Federal do Amazonas (Ufam). A metodologia utilizada foi de abordagem qualitativa, estudo de caso com aplicação de questionário aos associados a Agroufam durante a sua 55ª edição. A pesquisa demonstrou a presença de alguns controles contábeis entre os participantes por meio do registro de dados referentes a produção e venda dos produtos ofertados. Todavia observou-se a falta de utilização dessas informações em benefício do próprio negócio.
Evaluación de competencias del docente universitario bajo la percepción de los estudiantes de Ingeniería Civil
Authors:   UNIVERSIDAD NACIONAL SANTIAGO ANTÚNEZ DE MAYOLO, PERÚ, Reyes Roque Reynaldo Melquiades
Published: November 2020

El objetivo general de este trabajo fue determinar la percepción que tienen los estudiantes sobre las competencias del docente universitario, según los factores de planificación, conducción y valoración del proceso de enseñanza aprendizaje. El diseño de investigación es no experimental, transversal y descriptivo; para lo cual se utilizó como instrumento de recolección de información la encuesta; la muestra para el estudio equivale a 250 alumnos del semestre 2019-II de la Escuela Profesional de Ingeniería Civil de la Facultad de Ingeniería Civil de la Universidad Nacional Santiago Antúnez de Mayolo, Huaraz Perú, seleccionados mediante el muestreo aleatorio simple. Los resultados del estudio muestran que los estudiantes en un 54.4% han percibido las competencias de los docentes a nivel general como bueno y muy bueno, lo que significa una aproximación significativa del proceso de enseñanza aprendizaje de acuerdo a las exigencias para lograr un nivel de calidad de la enseñanza universitaria. Palabras clave: evaluación; competencias; percepción; docente; estudiantes.
ASIMILASI NARAPIDANA Vs KERESAHAN MASYARAKAT PASCA PELEPASAN NARAPIDANA SAAT COVID 19
Authors: Utami Wiwik
Published: November 2020

Tulisan yang didasarkan penelitian ini bertujuan untuk mengetahui persepsi masyarakat terhadap kebijakan pemerintah dalam pelepasan narapidan dengan assmilasi saat covid 19. Peneltian ini hukum sosiologis (socio legal research) dengan menggunakan data sekunder,didukung data primer yang diperoleh  dengan cara studi literasi dari berbagai sumber online, wawancara dengan beberapa informan, baik dari kepolisian Polresta Malang, kalangan kampus maupun masyarakat umumnya yang merasakan keadaan dengan assimilasi Narapidana saat Covid 19. Daerah penelitian  pada wilayah kerja Polresta Malang, hal ini didasarkan bahwa Kota Malang sangat padat penduduknya, ada 3 rumah tahanan (Lapas Lowokwaru, Lapas Wanita Sukun dan rumah tahanan polresta),  dan terdapat lebih dari 50 kampus, baik Perguruan Tinggi Negeri maupun Swasta, dimana kondisi ini rawan tindak kejahatan berupa pencurian (curanmor) maupun tindakan kekerasan lainnya, disamping cukup potensial untuk merebahnya virus corona (covid 19) melalui proses interaksi sosial di antara anggota masyarakat. Teknik atau metode analisis dan pengolahan bahan hukum yang digunakan adalah analisis kualitatif yang bersifat deskriptif. Hasil penelitian menunjukkan masyarakat merasakan keresahan dan ketakutan berlapis, baik dengan penyebaran covid 19 maupun terhadap Narapidana assimilasi yang idbebaskan. Kebijakan ini terkesan kurang terdukung oleh kajian akademis yang memadahi.

 

Kata kunci: Assimilasi Narapidana,  keresahan masyarakat ,Covid 19
COLORECTAL CANCER COMPLICATED BY OBSTRUCTION: INTESTINAL STOMA OR PRIMARY ANASTOMOSIS?
Authors: Akhmetzyanov Foat , Yegorov Vasiliy
Published: November 2020

Colorectal cancer (CRC) is one of the most common malignant tumors with increase in morbidity. Since this disease is often diagnosed in advanced stages more than 60% of cases have complications, the most common of them is obstruction. The presence of intestinal obstruction has a direct impact on the type and scope of surgery and almost always ends with the formation of intestinal stoma. Because of significant shortcomings of intestinal stomas for a patient, in the presence of obstruction some surgeons have resorted to the formation of primary colonic anastomoses. The key in this case is the state of the colon wall and adequate its purification from faeces and gases by means of various techniques of intraoperative colonirrigation. This work is devoted to the analysis of literature on intestinal obstruction of tumor genesis. However it does not relate to issues with decompensated bowel obstruction when the formation of intestinal stoma is not in doubt.
HARMONIZED STATISTICAL ANALYSIS OF THE EFFICACY OF INTRAPERITONEAL CHEMOTHERAPY REGIMENS WITH DIOXADET ON ASCITIC OVARIAN CANCER MODEL
Authors: Bespalov Vladimir , Belyaev Aleksey , Baranenko Denis , Khromov-borisov Nikita , Aleksandrov Valeriy , Krasilnikova Larisa , Kireeva Galina , Belyaeva Olesya , Senchik Konstantin , Stukov Aleksandr , Vasileva Irina , Semenov Aleksandr , Tochilnikov Grigoriy , Alvovskiy Ivan , Vyshinskaya Ye.
Published: November 2020

A comparative statistical study of the results of eight independent experiments on the efficacy of intraperitoneal chemotherapy has been performed. The regiments of cathether intraperitoneal chemotherapy (CIPC), normothermic and hyperthermic chemoperfusion (NIPEC and HIPEC) with antitumor drug dioxadet were investigated in 288 female Wistar rats with ascitic ovarian cancer. Ovarian cancer was transplanted intra-peritoneally (i.p.) 48 hours prior to a single chemotherapy at a number of 1*107 tumor cells. Dioxadet was administered at the maximum tolerated doses: CIPC - via syringe - 1.5 mg/kg body weight; NIPEC (36,5-37,5°С) and HIPEC (40,5-41,5°С) - infused for a continuous circulation using an experimental setting - at respective doses 30 and 15 mg/kg body weight. The rats in the control groups were administered in the same manner with physiological saline solution. The antitumor effects of the treatment were estimated as an increase in survival time. The statistical analysis was based on the principles of harmonization of statistical evidence and predictions. The mean survival time in the control group without treatment (i.p. saline injection) was 15 days with 95% confidence interval (CI) from 12 to 19 days. IPC, NIPEC and HIPEC increased mean survival time by 85, 97 and 202% (p
Dichromothrips corbetti (Priesner, 1936) (Thysanoptera: Thripidae): uma nova praga quarentenária em orquídeas no Brasil
Authors: Cavalleri Adriano , Alves Rogério M. de O. , Fabrício B. Lima Élison
Published: November 2020

Dichromothrips corbetti (Priesner, 1936) (Thysanoptera: Thripidae): a new quarantine pest in orchids in Brazil

Dichromothrips corbetti (Priesner, 1936), listed as quarantine pest by the Brazilian Ministry of Agriculture, is recorded for the first time in Brazil. Specimens were first detected in the state of Bahia causing chlorosis and deformation on leaves, flowers and flower buds of Vanda and Mokara and Aranda orchids. This thrips species is native to Southeast Asia, but widely reported in countries of Europe and Oceania. This is the first record of D. corbetti in South America.
LEARNING BY DOING MEDIA BELAJAR JAM DINDING DALAM PEMBELAJARAN MATEMATIKA DI KELAS 2 MIN 3 BANYUMAS
Authors: Faujatun Nahdiyah
Published: November 2020

The research was carried out the lock of student’s abilities in understanding time unit. Time unit is abstract, so it’is needed real object as a model to make the student understand easily.in other hand, the student should be given real activity that can be recreved easily. In order to make them understand the concept of time unit.The success of a teaching and learning process is one of the reasons due to the use of media or participation in the teaching and learning process. Because in the teaching and learning process media has an important meaning.This research used a qualitative method, and used  wall clock that made by paper carton. With a wall clock made of cardboard, it is easy for students to use the clock by rotating the direction of the needle on the cardboard between the long needle and the short needle must match.