bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Novel Domino Approach to Fluorescent Pyrimido[1,6‐a]indolones.
Authors: Facoetti Diego , Abbiati Giorgio , d'Avolio Laura , Ackermann Lutz , Rossi Elisabetta
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Three‐Component Protocol for the Synthesis of Novel Spiro‐oxazinobarbiturates.
Authors: Teimouri Mohammad Bagher , Abbasi Tayyebeh , Ahmadian Saloomeh , Heravi Mohammad Reza Poor , Bazhrang Reihaneh
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Reactivity of Dihydropyrazine Derivatives. Cycloaddition Behavior Toward Ketenes.
Authors: Nakahara Kazuhide , Yamaguchi Koki , Yoshitake Yasuyuki , Yamaguchi Tadatoshi , Harano Kazunobu
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2,6‐Disubstituted Pyrido[2,3‐b][1,4]oxazines.
Authors: Nishiwaki Nagatoshi , Hisaki Masataka , Ono Masaki , Ariga Masahiro
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design and Synthesis of (2R,3S)‐Iodoreboxetine Analogues for SPECT Imaging of the Noradrenaline Transporter.
Authors: Jobson Nicola K. , Crawford Andrew R. , Dewar Deborah , Pimlott Sally L. , Sutherland Andrew
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Yielding Synthesis of Nefopam Analogues (Functionalized Benzoxazocines) by Sequential One‐Pot Cascade Operations.
Authors: Ramachary Dhevalapally B. , Narayana Vidadala V. , Prasad M. Shiva , Ramakumar Kinthada
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Accelerated Iridium‐Catalyzed Borylation of Aromatic C—H Bonds.
Authors: Harrisson Peter , Morris James , Marder Todd B. , Steel Patrick G.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrophilic Fluorocyclization of Allyl Silanes.
Authors: Wilkinson Susan C. , Lozano Oscar , Schuler Marie , Pacheco Maria C. , Salmon Roger , Gouverneur Veronique
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regio‐ and Stereoselective Synthesis of Multisubstituted Vinylsilanes via Zirconacycles.
Authors: Nishihara Yasushi , Saito Daisuke , Tanemura Kenki , Noyori Shintaro , Takagi Kentaro
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Regio‐ and Stereoselective Fluorohydroxylation Reaction of 3‐Aryl‐1,2‐allenyl Phosphine Oxides with Selectfluor.
Authors: He Guangke , Fu Chunling , Ma Shengming
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of Modular Amino Acid Derivatives Containing Selenium with Pronounced GPx‐Like Activity.
Authors: Alberto Eduardo E. , Soares Letiere C. , Sudati Jessie H. , Borges Antonio C. A. , Rocha Joao B. T. , Braga Antonio L.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Radical‐Mediated Stannylation of Vinyl Sulfones: Access to Novel 4′‐Modified Neplanocin A Analogues.
Authors: Kumamoto Hiroki , Deguchi Kazuki , Wagata Tadashi , Furuya Yuu , Odanaka Yuki , Kitade Yukio , Tanaka Hiromichi
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Syntheses of (+)‐ and (‐)‐Pestalotiopsin A (I).
Authors: Takao Ken‐ichi , Hayakawa Nobuhiko , Yamada Reo , Yamaguchi Taro , Saegusa Hiroshi , Uchida Masatoshi , Samejima Suguru , Tadano Kin‐ichi
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Improved Practical Synthesis of Protected α‐Amino Selenocarboxylates and Its Application to the Synthesis of N‐(α‐Aminoacyl)sulfonamides.
Authors: Wu Xinghua , Chen Yu , Hu Longqin
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Approach to the Synthesis of anti‐β2,3‐Amino Acids: Application of β‐Trifluoroacetamidoorganozinc Reagents.
Authors: Bartrum Hannah E. , Jackson Richard F. W.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Glycosylated Vinyl Ethers by the Julia—Lythgoe‐Kocienski Olefination: Application to the Synthesis of 2′,5′‐Dideoxydisaccharides and Carbohydrated β‐Lactams.
Authors: Sanchez Ivan Perez , Turos Edward
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐O‐Benzylation in D‐Gluconamide Derivative under Basic Conditions with Complete Retention of Stereo‐Integrity: Convenient Access to 2‐O‐Benzyl‐3,4:5,6‐di‐O‐isopropylidene‐D‐glucitol and Other Differently Protected D‐Glucitol Derivatives.
Authors: Manjunath B. N. , Harikrishna K. , Aidhen Indrapal Singh , Varghese B.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Brevianamide J, a New Indole Alkaloid Dimer from Fungus Aspergillus versicolor.
Authors: Li Guo‐You , Tang Tao , Luo Ying‐Gang , Chen Xiao‐Zhen , Fang Dong‐Mei , Zhang Guo‐Lin
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereocontrolled Synthesis of the DEFG‐Ring Skeleton of Gambieric Acids.
Authors: Fuwa Haruhiko , Noji Sayaka , Sasaki Makoto
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Schisanwilsonins A—G and Related anti‐HBV Lignans from the Fruits of Schisandra wilsoniana.
Authors: Ma Wen‐Hui , Lu Yan , Huang Hai , Zhou Pei , Chen Dao‐Feng
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tausalarin C (I): A New Bioactive Marine Sponge‐Derived Nitrogenous Bismacrolide
Authors: Bishara Ashgan , Rudi Amira , Goldberg Israel , Aknin Maurice , Neumann Drorit , Ben‐Califa Nathalie , Kashman Yoel
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Isatin Derivatives, a Novel Class of Transthyretin Fibrillogenesis Inhibitors.
Authors: Gonzalez Asensio , Quirante Josefina , Nieto Joan , Almeida Maria Rosario , Saraiva Maria Joao , Panas Antoni , Arsequell Gemma , Valencia Gregorio
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tube‐in‐Tube and Wire‐in‐Tube Nano Building Blocks: Towards the Realization of Multifunctional Nanoelectronic Devices.
Authors: Ishai Moshit Ben , Patolsky Fernando
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design, Synthesis, and Structure—Activity Relationship of Novel Orally Efficacious Pyrazole/Sulfonamide Based Dihydroquinoline γ‐Secretase Inhibitors.
Authors: Probst Gary D. , et al. et al.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A High‐Magnetic‐Field‐Induced Density‐Wave State in Graphite
Authors: Yaguchi Hiroshi , Singleton John
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fractionation of Radionuclide Species in the Environment
Authors: Salbu Brit
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polyoxomolybdates and Polyoxomolybdovanadates — From Structure to Functions: Recent Results
Authors: Cindric Marina , Veksli Zorica , Kamenar Boris
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Silicate Minerals from Macedonia. Complementary Use of Vibrational Spectroscopy and X‐Ray Powder Diffraction for Identification and Detection Purposes
Authors: Jovanovski Gligor , Makreski Petre , Kaitner Branko , Boev Blazo
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Carbanion Reactions: Formation and Reaction of Carbanions from Ester or Amide Equivalents Using Catalytic Amounts of Bases
Authors: Kobayashi Shu , Matsubara Ryosuke
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Green Fluorescent Protein: Structure, Folding and Chromophore Maturation
Authors: Craggs Timothy D.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interrupting the Nazarov Reaction: Domino and Cascade Processes Utilizing Cyclopentenyl Cations
Authors: Grant Tina N. , Rieder Curtis J. , West Frederick G.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Glycosultransferase Inhibitors
Authors: Kajimoto Tetsuya , Node Manabu
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Research Developments on Acrylamide: Analytical Chemistry, Formation Mechanism, and Mitigation Recipes
Authors: Zhang Yu , Ren Yiping , Zhang Ying
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Approaches to the Neuraminidase Inhibitors Zanamivir (Relenza) and Oseltamivir Phosphate (Tamiflu) for the Treatment of Influenza
Authors: Magano Javier
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Natural Product Synthesis Using Multicomponent Reaction Strategies
Authors: Toure Barry B. , Hall Dennis G.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Peptidomimetics — A Versatile Route to Biologically Active Compounds
Authors: Grauer Andreas , Koenig Burkhard
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Porphyrin‐Based Catenanes and Rotaxanes
Authors: Sauvage Jean‐Pierre , Collin Jean‐Paul , Faiz Jonathan A. , Frey Julien , Heitz Valerie , Tock Christian
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of Hymenialdisine, Analogues and Their Evaluation as Kinase Inhibitors
Authors: Nguyen T. N. T. , Tepe J. J.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereocontrolled Alkylation of Unsaturated Compounds with Alkoxytitanacyclopropane Reagents
Authors: Kulinkovich Oleg , Isakov Vladimir , Kananovich Dzmitry
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bimacrocyclic Concave N‐Heterocyclic Carbenes (NHCs): Synthesis, Structure and Application in Catalysis
Authors: Winkelmann Ole , Luning Ulrich
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Stabilization of Fused‐Pentagon Fullerene Molecules
Authors: Tan Yuan‐Zhi , Xie Su‐Yuan , Huang Rong‐Bin , Zheng Lan‐Sun
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Formation of C—C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation: Vinylation, Allylation, and Enolate Addition
Authors: Patman Ryan L. , Bower John F. , Kim In Su , Krische Michael J.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iridium‐Mediated Alkane Dehydrogenation
Authors: Morales‐Morales David
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iridium‐Catalyzed Cycloadditions
Authors: Shibata Takanori
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iridium‐Catalyzed Coupling Reactions
Authors: Ishii Yasutaka , Obora Yasushi , Sakaguchi Satoshi
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Tricks in Amino Acid Synthesis: Applications to Complex Natural Products
Authors: Williams Robert M. , Burnett Cameron M.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitrilase and Nitrile Hydratase Catalyzed Enantioselective Preparation of Non‐Proteinogenic Amino Acids
Authors: Klempier Norbert , Winkler Margit
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Kinetics of Oxidative Coupling of Methane: Bridging the Gap Between Comprehension and Description
Authors: Sinev M. Yu. , Fattakhova Z. T. , Lomonosov V. I. , Gordienko Yu. A.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: From Peptides to Non‐Peptide α‐Helix Inducers and Mimetics
Authors: Haridas V.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Impact of Genomics on the Exploitation of the Myxobacterial Secondary Metabolome
Authors: Wenzel Silke C. , Mueller Rolf
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Genomics of Secondary Metabolite Production by Pseudomonas spp
Authors: Gross Harald , Loper Joyce E.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organotin Compounds as Anion‐Selective Carriers in Chemical Sensors
Authors: Chaniotakis Nikos
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Elucidation of Lipid Complex Formation Mechanisms by Static/Dynamic Structural Evaluation
Authors: Nakano Minoru
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pharmacological Studies on Responsiveness of 5‐Hydroxytryptamine to Overcome Perioperative Spasm of Coronary Artery Bypass Graft
Authors: Tanaka Naoko
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Morita—Baylis—Hillman Reaction: Insights into Asymmetry and Reaction Mechanisms by Electrospray Ionization Mass Spectrometry
Authors: Carrasco‐Sanchez Veronica , Simirgiotis Mario J. , Santos Leonardo S.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Vibrations of the S—S Bond in Elemental Sulfur and Organic Polysulfides: A Structural Guide
Authors: Trofimov Boris A. , Sinegovskaya Lidiya M. , Gusarova Nina K.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Characteristics of Hazardous Industrial Waste
Authors: Shammas Nazih K.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Gender‐Related Differences in Coronary Artery Dimensions: A Volumetric Analysis
Authors: Dickerson Jennifer A. , Nagaraja Haikady N. , Raman Subha V.
Published: December 2009

Background

Women consistently have poorer revascularization outcomes and more coronary vascular complications compared to men. This has been attributed to smaller coronary arteries, though limited data exist to support this assumption.

Hypothesis

By using volumetric data obtained from multidetector cardiovascular computed tomography (CCT), we sought to determine to what extent gender influences coronary artery dimensions and test the hypothesis that women would have smaller coronary dimensions even after normalizing for body surface area and cardiac mass.

Methods

CCT examinations completed on a 64‐slice scanner were identified from a university cardiovascular database. Data sets from 50 women and 44 men without coronary artery disease were selected for analysis. Cross‐sectional areas of proximal and distal segments of the left anterior descending (LAD), circumflex (LCx), and right coronary artery (RCA) were measured, blinded to patient gender. Measurements were compared using 2‐sample t tests and linear regression analysis techniques accounting for body surface area (BSA) and left ventricular (LV) mass.

Results

Analysis of cross‐sectional coronary artery areas, unadjusted for BSA and LV mass showed smaller coronary artery size in women compared to men in the proximal portion of both the LAD (P = .01) and RCA (P = .002), but no significant difference in the remaining coronary segments.

Conclusion

Gender significantly impacts proximal LAD and RCA size. Differences in coronary artery dimensions may explain some, but not all excess gender‐related risk with coronary artery revascularization, underscoring the importance of considering multiple contributing factors. Copyright © 2010 Wiley Periodicals, Inc.
Epidemiological Association between Uric Acid Concentration in Plasma, Lipoprotein(a), and the Traditional Lipid Profile
Authors: Lippi Giuseppe , Montagnana Martina , Luca Salvagno Gian , Targher Giovanni , Cesare Guidi Gian
Published: December 2009

Background

Elevated levels of uric acid in serum (SUA) or plasma (PUA) are increasingly related to cardiovascular disease. It is unclear whether they are independent risk factors or simply markers, reflecting association with other traditional risk factors.

Methods

We retrospectively assessed results of a lipid profile, including total cholesterol, low‐density lipoprotein cholesterol (LDL‐C), high‐density lipoprotein cholesterol (HDL‐C), triglycerides, total cholesterol to HDL‐C ratio (TC/HDL‐C), the atherogenic index of plasma (AIP), and lipoprotein(a) (Lp[a]), in a large cohort of unselected adult outpatients.

Results

Hyperuricemic men displayed significantly increased values of triglycerides and AIP when compared with men with normal PUA levels. In hyperuricemic women, significant differences were observed for HDL‐C, triglycerides, TC/HDL‐C, and AIP compared with women with normal PUA levels. The percentage of patients with unfavorable values was statistically higher for triglycerides and AIP in hyperuricemic men; for HDL‐C, triglycerides, TC/HDL‐C, and AIP in hyperuricemic women. In multivariable linear regression analysis triglycerides, AIP, and TC/HDL‐C were independently associated with PUA in women, whereas no significant association was observed in men.

Conclusion

PUA measurement might be advisable in patients to identify those at increased risk of cardiovascular disease (CVD) who might benefit from further triage and intervention. Copyright © 2010 Wiley Periodicals, Inc.
Irreversible End‐stage Heart Failure in a Young Patient due to Severe Chronic Hypocalcemia Associated with Primary Hypoparathyroidism and Celiac Disease
Authors: Mavroudis Konstantinos , Aloumanis Kyriakos , Stamatis Panagiotis , Antonakoudis George , Kifnidis Konstantinos , Antonakoudis Chariton
Published: December 2009

Background

Chronic hypocalcemia may cause electrocardiographic (ECG) changes and mimic acute myocardial infarction. It has also been associated with reversible cardiac dysfunction. On the other hand cardiomyopathy and heart failure have been reported in patients with idiopathic hypoparathyroidism or celiac disease.

Clinical Case

A 39‐year‐old male was admitted to the emergency room with acute retrosternal pain and dyspnea. He exhibited severe hypocalcemia and acute renal failure. High creatine kinase (CK) levels did not correlate with biomarkers of myocardial necrosis (negative troponin test, heart type creatine kinase isoenzyme (CK‐MB) < 1% of CK value). The ECG showed an extremely long QT interval (0.6 sec) and T‐wave inversions on V4 through V6. The left ventricular ejection fraction (LVEF) was as low as 25%, while coronary angiography was normal. Investigation of the hypocalcemia revealed primary hypoparathyroidism (Parathyroid hormone (PTH) < 3 pg/ml) and concomitant celiac disease with positive antigliadin and endomysial antibodies. The cardiovascular episodes and the dilated heart failure were attributed to the chronic hypocalcemia since no other cause was found. The correction of hypocalcemia has not been sufficient to reverse the end‐stage heart failure after more than 6 months of treatment, even though ECG abnormalities have receded, implying permanent cardiac impairment.

Conclusion

This case demonstrates an unusual clinical condition where 2 calcium homeostasis disorders led to severe hypocalcemia with clinical manifestations of end‐stage heart failure. The severe cardiac failure appeared to be nonreversible after calcium repletion suggesting permanent cardiac muscle dysfunction due to associated cardiomyopathy. Copyright © 2010 Wiley Periodicals, Inc.
Myocardial Perfusion Profile in a Young Population With and Without Known Coronary Artery Disease: Comparison by Gender
Authors: Zafrir Nili , Mats Israel , Solodky Alejandro , Kornowski Ran , Sulkes Jaqueline , Battler Alexander
Published: December 2009

Background

More and more young people are being referred for evaluation or screening for coronary artery disease (CAD). However, the value of myocardial perfusion imaging (MPI) in this population is unclear, especially in the absence of symptoms.

Methods

The study sample included 1765 consecutive patients less than 51 years old who were referred to a major medical center for stress/rest MPI study. Clinical and MPI variables were compared between patients with and without known CAD, by gender.

Results

There were 1346 (76%) men and 419 (24%) women of mean age 44 ± 6 years; 461 (26%) had known CAD. Stress‐induced ischemia was detected in 321 patients (18.2%) and significant ischemia in 131 (7.4%); there was no difference in the rate or severity of ischemia by presence of symptoms. Among those without known CAD, the rate of stress‐induced ischemia by MPI was significantly lower in women than men. On logistic regression analysis, the independent predictors of ischemia in men were high cholesterol, diabetes, angina during stress testing, ST depression, and smoking (P<.0001); and in women, the independent predictors were diabetes and high cholesterol.

Conclusion

Known CAD and stress‐induced ischemia are significantly more prevalent in young men than in young women, irrespective of risk factors. The independent predictors of ischemia differ between men and women. Copyright © 2010 Wiley Periodicals, Inc.
Slow Heart–Slow Brain: Consequence of Short‐term Occupational Exposure to Toluene in a Young Woman: What Is The Real Mechanism?
Authors: Türkoğlu Cengizhan , Aliyev Farid , Çeliker Cengiz , Uzunhasan Işıl , Kocaş Cuneyt
Published: December 2009

Herein we describe a case of acute occupational exposure to toluene in a 27‐year‐old female patient, presented to the emergency department of our institute. On admission she had electrocardiographic signs of profound sinus bradycardia with sinus arrhythmia and low amplitude slow wave activity recorded on her electroencephalogram (EEG). The mechanisms underlying the cerebral and cardiac effects of toluene are also discussed. Copyright © 2010 Wiley Periodicals, Inc.
Heparin‐Induced Thrombocytopenia Associated With Pulmonary Embolism
Authors: Mumoli Nicola , Cei Marco
Published: December 2009

Type II heparin‐induced thrombocytopenia (HIT) is a potentially severe adverse effect of heparin treatment triggered by an immune response. Although most cases occur in patients receiving unfractioned heparin, HIT can also arise after low‐molecular‐weight heparin (LMWH). We report a case of HIT in a postoperative orthopedic 75‐year‐old woman in treatment with LMWH (nadroparin) complicated by pulmonary embolism and treated successfully with recombinant hirudin. Early recognition and proper treatment are fundamental for the management of this life‐threatening disorder. Copyright © 2010 Wiley Periodicals, Inc.
Heart Rate Recovery and Tissue Doppler Echocardiography in Heart Failure
Authors: Guazzi Marco , Myers Jonathan , Ann Peberdy Mary , Bensimhon Daniel , Chase Paul , Pinkstaff Sherry , Arena Ross
Published: December 2009

Background

Previous research has demonstrated the prognostic value of echocardiography with tissue Doppler imaging (TDI) in the heart failure (HF) population. Heart rate recovery (HRR) has also recently shown promise as a prognostic marker.

Hypothesis

We hypothesize echocardiography with TDI and HRR will be significantly correlated and both will provide prognostic information.

Methods

A total of 243 subjects underwent echocardiography with TDI and maximal exercise testing to determine: (1) the ratio between mitral early (E) to mitral annular (E′) and E to mitral late (A) velocity; (2) left ventricular ejection fraction (LVEF); (3) left ventricular (LV) mass; (4) LV end‐systolic volume (LVESV); and (5) HRR at 1 minute postexercise (HRR1).

Results

HRR1 was significantly correlated with LVEF (r = 0.14, P = .03), LV mass (r = − 0.30, P <.001), E/A (r = − 0.22, P = .001), and E/E′ (r = − 0.49, P <.001). Multivariate Cox regression analysis revealed HRR1 was the strongest predictor of cardiac mortality (χ2: 55.5, P <.001); LV mass (residual χ2: 13.1, P <.001), E/E′ (residual χ2: 11.2, P = .001), and LVESV (residual χ2: 5.9, P = .015) all added significant prognostic value and were retained in the regression while LVEF was removed (residual χ2: 0.008, P = .93).

Conclusions

To our knowledge, this is the first investigation demonstrating an association between HRR and variables obtained from echocardiography with TDI in subjects with HF. The combination of both assessment techniques provides improved prognostic discrimination. Copyright © 2010 Wiley Periodicals, Inc.
Rest Myocardial Perfusion Imaging in a Patient with Atypical Chest Pain and a Nondiagnostic Electrocardiogram
Authors: Grube Heinrich , Rosenblatt Jeffrey
Published: December 2009

ACC/AHA guidelines assign a class I indication for use of myocardial perfusion imaging (MPI) for the evaluation of chest pain in patients with acute coronary syndromes and a nondiagnostic ECG. However, MPI is not a widely used modality for the evaluation of patients who present to the ER with chest pain and an intermediate pretest probability for coronary artery disease.

We report a case in which resting MPI was pivotal in diagnosing acute myocardial infarction and expedited the appropriate reperfusion strategy. Copyright © 2010 Wiley Periodicals, Inc.
Sleep Disordered Breathing is Associated with Appropriate Implantable Cardioverter Defibrillator Therapy in Congestive Heart Failure Patients
Authors: Tomaello Luca , Zanolla Luisa , Vassanelli Corrado , LoCascio Vincenzo , Ferrari Marcello
Published: December 2009

Background

Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population.

Hypothesis

To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients.

Methods

A total of 22 consecutive ICD patients with systolic CHF (left ventricular ejection fraction [LVEF]< 45%) were studied by polysomnography.

Results

A total of 17 (77.2%) showed SDB (apnea‐hypopnea index [AHI]_ 10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = − 0.619; P = .003, respectively).

Conclusions

Sleep disordered breathing is frequent in ICD recipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges. Copyright © 2010 Wiley Periodicals, Inc.
Congenital Complete Absence of the Left Pericardium: A Rare Cause of Chest Pain or Pseudo‐right Heart Overload
Authors: Garnier Fabien , Eicher Jean‐Christophe , Philip Jean‐Luc , Lalande Alain , Bieber Hubert , Voute Marie‐France , Brenot Roger , Brunotte François , Wolf Jean‐Eric
Published: December 2009

Background

Congenital defects of the pericardium are rare and poorly known cardiac malformations. Most of them are left‐sided and asymptomatic and are usually incidentally diagnosed.

Aims

To describe the clinical, electrocardiographic, and imaging features of total absence of the left pericardium.

Methods and Results

We report the cases of 3 patients who have been seen in our institution with a diagnosis of total congenital absence of the pericardium. All of them complained of precordial pain; one of them experienced disabling symptoms that justified surgical intervention. All of them had previously been suspected to have an atrial septal defect because of the echocardiographic appearance of right ventricular volume overload. Electrocardiogram, chest x‐ray, echocardiography, and magnetic resonance imaging of the heart consistently showed remarkably similar features including leftward displacement, increased mobility, and interposition of lung tissue between the heart and other intrathoracic structures.

Conclusion

Congenital absence of the left pericardium should be known by clinicians as a possible differential diagnosis of chest pain or pseudo‐right heart overload. Copyright © 2010 Wiley Periodicals, Inc.
The Efficacy of Statin Therapy in Patients with Acute Coronary Syndromes and Concomitant Carotid Disease
Authors: Komorovsky Roman , Desideri Alessandro , Coscarelli Sebastian , Tonello Diego , Visonà Adriana , Celegon Leopoldo
Published: December 2009

Background

Statins prevent recurrent ischemic coronary events after acute coronary syndrome (ACS) and improve cardiovascular outcome of patients with peripheral artery disease.

Aim

We sought to evaluate the interrelationship between statin use, phenotype of carotid plaques as assessed by ultrasound, and outcome of patients with ACS and concomitant carotid disease.

Methods

A total of 337 consecutive patients with ACS were assessed by coronary angiography and Doppler ultrasound of the carotid arteries and followed up for a median period of 19 months.

Results

Carotid plaques were detected in 144 (42%) patients. Of these patients, 99 (69%) had echogenic carotid plaques and 45 (31%) had echolucent plaques. The groups did not differ significantly with regard to the lipid profiles, the prevalence of risk factors, and 1‐vessel, 2‐vessel, or 3‐vessel coronary artery disease. During follow‐up, 227 (67%) patients were receiving statins. We observed 14 cardiac deaths and 17 myocardial infarctions. After adjustment for treatment strategy (medical therapy or myocardial revascularization), patients with echolucent carotid plaques receiving statin therapy (n = 32, 71%) showed a better event‐free survival than did patients with echolucent plaques not treated with statins (log‐rank P = .038). In patients with echogenic carotid plaques, the benefit of statin therapy on event‐free survival was less evident (log‐rank P = .56).

Conclusion

In patients with ACS and echolucent carotid plaques, statin therapy is associated with better event‐free survival, while in patients with ACS and echogenic carotid plaques no clear benefit of statins is observed. Copyright © 2010 Wiley Periodicals, Inc.
A Novel Noninvasive Ultrasonic Cardiac Output Monitor: Comparison With Cardiac Magnetic Resonance
Authors: Trinkmann Frederik , Doesch Christina , Papavassiliu Theano , Weissmann Joerg , Haghi Dariusch , Gruettner Joachim , Schoenberg Stefan O. , Borggrefe Martin , Kaden Jens J. , Saur Joachim
Published: December 2009

Background

USCOM, a novel continuous wave Doppler (CWD) device, has been introduced for noninvasive determination of cardiac output (CO). The present study aimed to compare the accuracy and reproducibility of the new device, using cardiovascular magnetic resonance imaging (CMR) as the noninvasive gold standard.

Methods and Results

The CO of 56 consecutive patients was prospectively determined by CWD either before or after CMR imaging. The CWD probe was placed in the suprasternal or supraclavicular notch aiming at the aortic valve. Valid CWD signals could be obtained in 45 patients yielding a CO of 5.3±1.1 L/min (range, 3.0–7.5 L/min) by CMR and 4.7±1.1 L/min by CWD (2.5–8.0 L/min, P = .004), respectively. CWD measurements showed an acceptable agreement with CMR (bias: 0.6±1.1 L/min) and a high reproducibility (bias: 0.1±0.4 L/min). Higher CO and body mass index (BMI) were identified as sources of inaccuracy in univariate analysis. By multivariate analysis, only COCMR was found to be independently associated with larger variation. Estimated diameters of the left ventricular outflow tract (LVOT), a prerequisite for CO measurement by CWD, correlated only weakly with those measured by CMR.

Conclusions

Continuous wave Doppler is a feasible technique for measuring cardiac function. Although the overall agreement with CMR was acceptable, CWD showed a trend to underestimate CO. The estimated LVOT diameter by CWD is likely to be an important source of error. Nevertheless, the CWD device could be of clinical use especially for detection of intraindividual hemodynamic changes since a high reproducibility could be demonstrated. Copyright © 2010 Wiley Periodicals, Inc.
Drink, Drugs, and the QT Interval
Authors: Weir Robin A. P. , Petrie Colin J. , Murphy Charles Angus , Dargie Henry J.
Published: December 2009

The effects of several prescription and illicitly‐used drugs on electrocardiographic repolarization are well documented, most frequently manifested as prolongation of the corrected QT (QTc) interval. The combination of multiple repolarization‐modulating drugs taken in high dosage can occasionally lead to extreme abnormalities of the QTc interval and ST‐segment on the surface ECG, which can lead to the erroneous diagnosis of underlying myocardial ischemia and inappropriate treatment. We report on one such case in which the acute management of a syncopal patient was detrimentally influenced by misinterpretation of a very unusual ECG. Copyright © 2010 Wiley Periodicals, Inc.