bluuebunny/crossref_metadata_2025 huggingface dataset:
Fe-rich X-ray amorphous material records past climate and persistence of water on Mars
Authors: Feldman Anthony D. , Hausrath Elisabeth M. , Rampe Elizabeth B. , Tu Valerie , Peretyazhko Tanya S. , DeFelice Christopher , Sharp Thomas
Published: July 2024

X-ray amorphous material comprises 15-73 wt.% of sedimentary rocks and eolian sediments in Gale crater. This material is variably siliceous and iron rich but aluminum poor. The presence of volatiles is consistent with the existence of incipient weathering products. To better understand the implications of this material for past aqueous conditions on Mars, here we investigate X-ray amorphous material formation and longevity within terrestrial iron rich soils with varying ages and environmental conditions using bulk and selective dissolution methods, X-ray diffraction, and transmission electron microscopy. Results indicate that in situ aqueous alteration is required to concentrate iron into clay-size fraction material. Cooler climates promote the formation and persistence of X-ray amorphous material whereas warmer climates promote the formation of crystalline secondary phases. Iron rich X-ray amorphous material formation and persistence on Mars are therefore consistent with past cool and relatively wet environments followed by long-term cold and dry conditions.
Altimetry-based ice-marginal lake water level changes in Greenland
Authors: Dømgaard Mads , Kjeldsen Kristian , How Penny , Bjørk Anders
Published: July 2024

Greenland holds over 3300 ice-marginal lakes, serving as natural reservoirs for outflow of meltwater to the ocean. A sudden release of water can largely influence ecosystems, landscape morphology, ice dynamics and cause flood hazards. While large-scale studies of glacial lake outburst floods (GLOFs) have been conducted in many glaciated regions, Greenland remains understudied. Here we use altimetry data to provide the first Greenland-wide inventory of ice-marginal lake water level changes, studying over 1100 lakes from 2003–2023, revealing a diverse range of lake behaviors. Around 60% of the lakes exhibit minimal fluctuations, while 326 lakes have drained, collectively contributing to 541 observed GLOFs from 2008–2022. These GLOFs vary substantially in magnitude and frequency, with the highest concentration observed in the North and Northeast regions. Our results show substantial annual differences in the number of GLOFs with a notable peak in 2019, coinciding with a year marked by extreme runoff. Our method detected a 1200% increase in the number of draining lakes compared to existing historical databases. This highlights a large underreporting of GLOF events and emphasizes the pressing need for a deeper understanding of the mechanisms behind and the consequences of these dramatic events.
Quantifying the interrelationships between physical, social, and cognitive-emotional components of mental fitness using digital technology
Authors: Iorfino Frank , Varidel Mathew , Capon William , Richards Matthew , Crouse Jacob J. , LaMonica Haley M. , Park Shin Ho , Piper Sarah , Song Yun Ju Christine , Gorban Carla , Scott Elizabeth M. , Hickie Ian B.
Published: July 2024

Mental fitness is a construct that goes beyond a simple focus on subjective emotional wellbeing to encompass more broadly our ability to think, feel, and act to achieve what we want in our daily lives. The measurement and monitoring of multiple (often interacting) domains is crucial to gain a holistic and complete insight into an individual’s mental fitness. We aimed to demonstrate the capability of a new mobile app to characterise the mental fitness of a general population of Australians and to quantify the interrelationships among different domains of mental fitness. Cross-sectional data were collected from 4901 adults from the general population of Australians engaged in work or education who used a mobile app (Innowell) between September 2021 and November 2022. Individuals completed a baseline questionnaire comprised of 26 questions across seven domains of mental fitness (i.e., physical activity, sleep and circadian rhythms, nutrition, substance use, daily activities, social connection, psychological distress). Network analysis was applied at both a domain-level (e.g., 7 nodes representing each cluster of items) and an individual item-level (i.e., 26 nodes representing all questionnaire items). Only 612 people (12%) were functioning well across all domains. One quarter (n = 1204, 25%) had only one problem domain and most (n = 3085, 63%) had multiple problem domains. The two most problematic domains were physical activity (n = 2631, 54%) and social connection (n = 2151, 44%), followed closely by daily activity (n = 1914, 39%). At the domain-level, the strongest association emerged between psychological distress and daily activity (r = 0.301). Psychological distress was the most central node in the network (as measured by strength and expected influence), followed closely by daily activity, sleep and circadian rhythms and then social connection. The item-level network revealed that the nodes with the highest centrality in the network were: hopelessness, depression, functional impairment, effortfulness, subjective energy, worthlessness, and social connectedness. Social connection, sleep and circadian rhythms, and daily activities may be critical targets for intervention due to their widespread associations in the overall network. While psychological distress was not among the most common problems, its centrality may indicate its importance for indicated prevention and early intervention. We showcase the capability of a new mobile app to monitor mental fitness and identify the interrelationships among multiple domains, which may help people develop more personalised insights and approaches.
Achieving efficient and stable blue thermally activated delayed fluorescence organic light-emitting diodes based on four-coordinate fluoroboron emitters by simple substitution molecular engineering
Authors: Li Panpan , Lai Shiu-Lun , Chen Ziyong , Tang Wai Kit , Leung Ming-Yi , Ng Maggie , Kwok Wing-Kei , Chan Mei-Yee , Yam Vivian Wing-Wah
Published: July 2024

A series of sky-blue to pure-blue fluoroboron thermally activated delayed fluorescence (TADF) emitters has been designed and synthesized. Their TADF efficiencies are manipulated through π-bridge engineering and N-donor modulation.
2,3-Diamino-4,5-diarylcyclopentadienone iron carbonyl complexes as catalysts for reductive amination reactions
Authors: Körner Lukas , Bockfeld Dirk , Bannenberg Thomas , Tamm Matthias
Published: July 2024

2,3-Diamino-4,5-diarylcyclopentadienones have been prepared and were used for the preparation iron pre-catalysts for the reductive amination of citronellal and for the diastereoselective synthesis of the anti-depressant sertraline.
Electronic regulation & improved conductivity of molecular catalysts as electrocatalysts
Authors: Bihua Hu , Hailin Cao , Zhiwei Lei , Shuyu Cui , Peizhi Wang , Jun Tang , Xingzhu Wang , Baomin Xu
Published: July 2024

Molecular catalysts supported by N-MXene with in situ oxidation have been synthesized by a simple method. Among them, CoPc/o-N-MXene exhibits superior activity and selectivity for ERCD to methanol.
Iron–cobalt nanoparticles dispersed in indium-based MIL-68-derived carbon nanosticks for water oxidation
Authors: Wang Haoran , Li Nan , Fu Yuting , Chen Junliang , Liu Jie , Yang Yuandong , Xu Shaojie , Qian Jinjie
Published: July 2024

Herein, the dispersed FeCo nanoparticles can be effectively encapsulated into an isostructural In-based MIL-68-derived carbon nanosticks, denoted as MIL-68-FeCo-C, which shows enhanced oxygen evolution performance.
The application of water bamboo (Zizania latifolia) husk-derived biochar for copper-contaminated irrigation water treatment and soil amendment
Authors: Nguyen Thi-Manh , Chen Hung-Hsiang , Yang Chih-Chi , Tsai Yung-Pin , Kuo Ming-Yu , Liao Yi-Tang , Chang Yu-Chen , Chen Ku-Fan
Published: July 2024

Biochar prepared from water bamboo husks can be used for water purification and soil acidification amendment to safeguard agricultural soil and increase crop yields in Taiwan.
Tuning the mechanical properties of molecular perovskites by controlling framework distortions via A-site substitution
Authors: Kronawitter Silva M. , Park Shinjoo , Hallweger Sebastian A. , Myatt Emily , Pitcairn Jem , Cliffe Matthew J. , Daisenberger Dominik , Drees Markus , Kieslich Gregor
Published: July 2024

In this work, we quantify the link between framework distortions and mechanical properties in molecular perovskites, showing that increasing framework distortions translates to a reduced compressibility.
A tilapia skin-derived gelatin hydrogel combined with the adipose-derived stromal vascular fraction for full-thickness wound healing
Authors: Luo Yanan , Fu Manfei , Zhou Ziyi , Zhang Xiaopei , Guo Qingxia , Wang Yawen , Zhang Weina , Wang Yuanfei , Chen Zhenyu , Wu Tong
Published: July 2024

SVF was combined with methacrylate-functionalized tilapia skin gelatin by UV irradiation to fabricate a three-dimensional scaffold composite FG-SVF hydrogel for the treatment of full-thickness skin trauma in rats.
Na6MCl8 rock-salt compounds with M = Mg, Ca, Ba, Zn, Sr as components for solid-state sodium ion batteries
Authors: Zulueta Yohandys A. , Pham-Ho My Phuong , Nguyen Minh Tho
Published: July 2024

Rock-salt compounds Na6MCl8 (M = Mg, Ca, Ba, Zn, Sr) for solid-state sodium ion batteries.
Recent developments in the synthesis and applications of terpyridine-based metal complexes: a systematic review
Authors: Kainat Syeda Fariha , Hawsawi Mohammed B. , Mughal Ehsan Ullah , Naeem Nafeesa , Almohyawi Abdulaziz M. , Altass Hatem M. , Hussein Essam M. , Sadiq Amina , Moussa Ziad , Abd-El-Aziz Alaa S. , Ahmed Saleh A.
Published: July 2024

Terpyridine-based metal complexes have emerged as versatile and indispensable building blocks in the realm of modern chemistry, offering a plethora of applications spanning from materials science to catalysis and beyond.
Cefiderocol susceptibility endows hope in treating carbapenem-resistant Pseudomonas aeruginosa: insights from in vitro and in silico evidence
Authors: Basu Soumya , Ashok Gayathri , Ghosh Soumyadip , Ramaiah Sudha , Veeraraghavan Balaji , Anbarasu Anand
Published: July 2024

Clinical carbapenemase-positive Pseudomonas aeruginosa strains showing pan-β-lactam resistance had stabilizing mutations in penicillin-binding protein-3. Cefiderocol however showed efficacy with low MIC-values due to multi-target specificity.
Machine learning empowered next generation DNA sequencing: perspective and prospectus
Authors: Mittal Sneha , Jena Milan Kumar , Pathak Biswarup
Published: July 2024

This perspective discusses the current landscape of machine learning (ML)-empowered next-generation DNA sequencing, including both theoretical and experimental aspects.
Win–win strategy: zinc-ion anchoring crosslinked hydrogels and regulating electronic structure to achieve V3+/V4+/V5+ redox reaction of Na3V2(PO4)3 with high thermal stability and zero strain characteristics
Authors: Zhou Tao , Zhang Baofeng , He Shengnan , Yang Yaxiong , Zheng Chao , Wang Yanzhong , Guo Li , Chen Yanjun
Published: July 2024

Zinc-ion anchoring crosslinked hydrogels and regulating electronic structure to achieve high performance of Na3V2(PO4)3.
Temperature self-compensation thin film strain gauges based on nano-SiO2/AgNP composites
Authors: Zhao Yang , Liu Jin , Ying Yuhuang , Chen Hongyu , Wang Wenxuan , Zhang Sijie , Hai Zhenyin , Sun Daoheng
Published: July 2024

Nano-SiO2/AgNP temperature self-compensation thin film strain gauges for micro-strain by direct ink writing technology.
Photo-polymerization-induced tightened domain enhancing the room-temperature phosphorescence emission
Authors: Yuan Cheng , Lee Sang Yup , Huang Jingyuan , Cho Yong Ho , Liu Yujie , Ahn Dong June , Cui Chunzhi
Published: July 2024

Diacetylene monomers are linked to pure organic phosphors (POPs), and the conjugated polydiacetylene formed by UV irradiation arranges the POPs tightly. This strategy significantly enhances the room-temperature phosphorescent efficiency of POPs.
Photo-induced room temperature phosphorescence and thermally activated photochromism based on thianthrene derivatives
Authors: Li Nan , Wang Yunsheng , Li Zhen
Published: July 2024

Thianthrene derivatives demonstrate reversible photochromism and photoinduced RTP, with TN-2Nap showing significant thermal control due to low reorganization energy and π-conjugation.
Importance of the curvature in electronic, structural and charge transport properties: oligomers of N-pyridine carbazole
Authors: Brouillac Clément , Serez Ari , McIntosh Nemo , Rault-Berthelot Joëlle , Jeannin Olivier , Heinrich Benoît , Quinton Cassandre , De Sagazan Olivier , Jacques Emmanuel , Cornil Jérôme , Poriel Cyril
Published: July 2024

The recent development of π-conjugated nanohoops in organic electronics has opened new perspectives for this family of curved materials.
Phase response constrained symbol‐level waveform design for dual‐functional radar‐communication systems
Authors: Zhang Tingxiao , Zhao Yongbo , Liu Donghe
Published: July 2024

In this letter, a novel algorithm is proposed to design symbol‐level waveform for dual‐functional radar‐communication (DFRC) systems with low range sidelobe. Different from current schemes design waveform at the block level, a phase response constraint is introduced at the symbol level to provide an additional degree of freedom to decrease the range sidelobe in the pulse compression procedure, which is highly desired in radar systems. In particular, the phase response at the target direction is constrained to be similar to the given reference phase, and the matching error between the designed beampattern and the desired one is minimized subject to the constant modulus constraint. Furthermore, to guarantee the quality of service for communication, constructive interference is exploited at the symbol level for each communication user. An alternating direction method of multipliers algorithm is also proposed to solve the resulting nonconvex optimization problem with tractable subproblems solved sufficiently by the manifold optimization and standard quadratic problem. Numerical simulation results demonstrate the performance of the proposed method.
Efficient high‐fidelity deep convolutional generative adversarial network model for received signal strength reconstruction in indoor environments
Authors: Wu Haochang , Ding Tairan , Qin Hao , Zhang Xingqi
Published: July 2024

With the rapid development of wireless communication systems, particularly in the era of 5G and the Internet of Things, deploying wireless communication networks in indoor environments has become crucial. Indoor infrastructure deployment necessitates innovative approaches for efficiently and accurately obtaining received signal strength (RSS) maps. However, traditional methods for acquiring RSS maps, such as empirical and deterministic models, are limited by significant inaccuracies and high computational demands. Empirical models often fail to capture the complex dynamics of indoor environments, resulting in deviations from actual signal behaviours. On the other hand, deterministic models, while more accurate, are computationally intensive due to their reliance on detailed physical modelling of wave propagation. This study introduces a machine learning approach based on deep convolutional generative adversarial networks (DCGAN) aimed at reconstructing indoor RSS maps with minimal RSS measurements. By leveraging DCGAN's generative and adversarial training capabilities, the method not only surpasses traditional interpolation methods in efficiency and precision but also offers new possibilities for the rapid deployment and optimization of wireless communication systems in indoor environments.
L’immunocytokine FAP-IL2v: Un co-traitement efficace pour pallier la résistance au trastuzumab du cancer du sein HER2+
Authors: Parisel Eléonore , Prudhomme Laura , Pol Jonathan
Published: July 2024

Dans le cadre de leur module d’analyse scientifique, des étudiants des promotions 2022-2023 et 2023-2024 des Master 2 « Immunologie Translationnelle et Biothérapies » (ITB) et « Immunologie Intégrative et Systémique » (I2S) (Mention Biologie Moléculaire et Cellulaire, Parcours Immunologie, Sorbonne Université) se sont penchés sur la littérature et ont pris la plume pour partager avec les lecteurs de m/s quelques-uns des faits marquants de l’actualité en immunologie. Voici une sélection de quelques-unes de ces nouvelles, illustrant la large palette des axes de recherche en cours sur les mécanismes physiopathologiques des maladies infectieuses, auto-immunes, inflammatoires et tumorales et sur le développement d’immunothérapies pour le traitement de ces pathologies.

On y découvre ainsi de nouvelles avancées sur l’analyse transcriptomique du microenvironnement inflammatoire de pathologies autoimmunes, sur des aspects mécanistiques impliqués dans la survie des cellules cancéreuses et la réponse immunitaire anti-tumorale des cellules NK, l’interconnexion entre le système immunitaire et le système nerveux périphérique, le développement de nouvelles immunothérapies permettant de cibler préférentiellement le microenvironnement tumoral et la prise en charge des effets secondaires autoimmuns cardiaques induits par les immunothérapies.

Toute l’équipe pédagogique remercie également chaleureusement les différents tuteurs, experts dans le domaine en lien avec les nouvelles, qui ont accompagné avec bienveillance et enthousiasme le travail de nos étudiants !
Journey to the Centre of the Ovale: A Novel, Combined Percutaneous Fluoroscopic and Image-Guided Approach to Biopsy a Meckel's Cave Lesion
Authors: Khan Amad , Anwar Durria , Hempenstall Jonathan , Vajramani Girish
Published: July 2024

Introduction The percutaneous Hartel's technique is a well-described approach to targeting lesions in the Meckel's cave. It is used as the standard approach for all percutaneous trigeminal neuralgia procedures for accessing the Gasserian ganglion through the foramen ovale, be it for a balloon compression, glycerol rhizolysis, or radiofrequency ablation. It has also been described in the literature as an approach to biopsy lesions in the Meckel's cave and cavernous sinus using fluoroscopic guidance; however, there were a significant number of nondiagnostic samples. No one to date has described a combined fluoroscopic and image-guided approach to improve safety and accuracy.

Methods The patient had a 3-month history of left-sided facial numbness and a left VIth palsy causing diplopia and a squint. The computed tomography of the chest, abdomen, and pelvis was unremarkable as were the serum tumor markers. We describe the novel approach of using a percutaneous biopsy needle to obtain a cytological sample of a Meckel's cave lesion using a combination of X-ray and electromagnetic image guidance with use of StealthStation S8 System (Medtronic Sofamor Danek, Memphis, Tennessee, United States). The need for a craniotomy and its associated morbidity and technical challenges was therefore obviated.

Results The procedure was performed under general anesthesia and eight core samples were sent to neuropathology for analysis. The lesion was histologically confirmed to be lymphoma, and the patient subsequently received oncological treatment. The patient had no immediate or postoperative complications, and the use of the aforementioned combined approach improved safety and accuracy of targeting the lesion in real time.

Conclusion A combined percutaneous fluoroscopic and image-guided approach to biopsy a Meckel's cave lesion is recommended, as it improves safety and accuracy.
Safety and Efficacy of Lipiodol and N-Butyl Cyanoacrylate (N-BCA) Combination for Vascular Embolization
Authors: Prasad Raghunandan , Marotrao Pole Shivaji , Sheorain Virender Singh , Gamanagatti Shivanand
Published: July 2024

Purpose The aim of this study was to evaluate the safety and efficacy of the combination of Lipiodol and N-butyl cyanoacrylate (N-BCA) for vascular embolization.

Methods Patients with various vascular pathologies, eligible for embolization using a combination of Lipiodol and N-BCA, were included in this ethical committee–approved prospective multicenter study. Adverse events (AEs) during the procedure and up to 30 days were recorded and categorized into minor or major (AE classification by the Society of Interventional Radiology). Depending on the targeted volume of vascular occlusion of the lesion, lesions were classified into four groups (group 1: <50% target volume; group 2: 50–75%; group 3: 75–99%, and group 4: 100%). Consistency between the targeted and actual vascular occlusion achieved after embolization was assessed.

Results One hundred and twenty-four patients were enrolled. All underwent at least one procedure, and 12 required a second procedure. No AEs were noted during the procedure, while 42 AEs occurred in 23 patients (18.5%) after and during the follow-up period. Two minor AEs in one patient (0.8%) were related to the mixture, and 26 AEs in 16 patients (12.9%) were related to the procedure (mostly minor A, 30.8% or B, 42.3%). The most frequent procedure-related AE was postembolization syndrome (4.8%). Nonfatal serious AEs related to the procedure occurred in two patients. The actual vascular occlusion was equal to or greater than the targeted volume in 119/135 lesions (88.1%) following the first procedure and in 11/13 lesions (84.6%) following the second procedure.

Conclusion Lipiodol and N-BCA combination is safe and highly effective for vascular embolization.
Success of Combination Therapy with Isavuconazole in a Pediatric Patient with Breakthrough Invasive Aspergillosis
Authors: Özen Seval , Yildiz Selin , Keçeli Avni Merter , Kanik-Yüksek Saliha , Güzelküçük Zeliha , Uzuntaş Sema Turan , Gülhan Belgin , Şahin Elif Ayça , Parlakay Aslı Nur Özkaya , Yarali Neşe
Published: July 2024

The increasing incidence of invasive fungal infections, coupled with the growing population of immunocompromised patients, has led to an increased need for antifungal agents. The newest azole, isavuconazole, plays an important role in the treatment of invasive aspergillosis in adults due to its broad spectrum, tolerability, and no need for therapeutic drug monitoring. This agent, which has not yet been approved for use in children, has significant problems with drug supply in Türkiye. We present the treatment response to isavuconazole combination therapy used in salvage treatment in a patient with breakthrough invasive aspergillosis, who had treatment failure with different antifungal combination treatment options and surgical resection.
Density functional theory study of the adsorption and dissociation of OF2 and O3 gases on the surface of pristine and Al, Ti and Cr doped graphene
Authors: Talha Abu , Shihab Fatin Hasnat , Ahmed Mohammad Tanvir , Al Roman Abdullah , Kowser Zannatul , Roy Debashis
Published: July 2024

In this research, we studied pristine (PGs) and Al, Ti, and Cr-doped graphene (DGs) via density functional theory calculations for adsorption of OF2 and O3 gas. Changes in the structural, electronic, and optical properties due to Al, Ti, and Cr-doping as well as gas adsorption have been studied. After doping with Al, Ti, and Cr atoms, the cohesive energies were −8.787, −8.754, and −8.768 eV, respectively, where the negative values indicate the structural stability of doped sheets. The OF2 adsorbed on the complexes of PGs, Ti-DGs, Cr-DGs, and Al-DGs showed strong adsorbate–adsorbent interaction with −0.468, −16.369, −11.096, and −9.158 eV adsorption energies, respectively. Similarly, for O3 gas, the adsorption energies of those sheets are −0.444, −10.575, −10.870, and −6.711 eV, respectively. From optical properties analysis, we found that the maximum reflectivity for gas-adsorbed Ti-DGs and Cr-DGs is found in the UV region, whereas the highest reflectivity for Ti-DGs and Cr-DGs is found in the visible range. Our studies reveal that all these DGs are good candidates for the adsorption and dissociation of OF2 and O3 gases.
Evaluation based on multi-criteria decision-making methods and spherical fuzzy framework for security and privacy in metaverse technologies: A case study
Authors: Hezam Ibrahim M. , Ali Ahmed M. , Sallam Karam , Hameed Ibrahim A. , Božanić Darko , Abdel-Basset Mohamed
Published: July 2024

Integrating the metaverse technology with the transportation system has several security and privacy issues. This study assesses the 12 security solutions to select the best one to overcome security and privacy issues (such as data theft, unauthorized access, and theft of personal data) when integrating the transportation system with metaverse technology. A suggested methodology is conducted by experts and decision-makers using linguistic terms and spherical fuzzy numbers to express their opinions on evaluating the criteria and alternatives. Selecting the best security solution (alternative) is critical because it includes several conflict security criteria, such as data theft, authentication, security attacks, and others. This paper introduces a methodology for multi-criteria decision-making (MCDM) in a spherical fuzzy (SF) environment. The MCDM method dealt with various conflicting criteria, and SF dealt with uncertainty and vague information while evaluating the criteria and alternatives. The suggested methodology consists of two main phases. The first phase introduces the analytic hierarchy process (SF-AHP) method to compute the criteria weights. The second phase introduces the Weighted Aggregates Sum Product Assessment (SF-WASPAS) method to rank and select the best alternative. The results show the end-to-end authentication protocol is the best alternative (security solution). This study conducted a sensitivity analysis of the stability of the rank by changing the criteria’s weights. The sensitivity analysis results show that the end-to-end authentication protocol is the best alternative (security solution) in different cases. We compare the suggested methodology with six other MCDM methods: SF-TOPSIS, SF-VIKOR, SF-MABAC, SF-CODAS, SF-MARCOS, and SF-COPRAS to show the effectiveness of the proposed method. The results show that the presented methodology is robust compared to other MCDM methods.
A community proactive health management model for family doctors in Shandong, China
Authors: Yang Meng
Published: July 2024

Background Chronic disease management is an essential part of public health management and a fundamental means of slowing down the progression of major diseases. Unlike traditional medical care, proactive health management focuses on the combination of prevention and treatment. Proactive health management can reduce the re-admission rate of patients with chronic diseases, improve long-term prognosis, and effectively reduce the disability and mortality rates of major health events. This study aimed to establish a proactive health management model based on a grid-based medical service team arrangement, and to explore the effect of this model on managing chronic diseases in community health service institutions. Methods A grid-based medical service team was established in Binzhou, Shandong, China, consisting of general practitioners, nurses, public health doctors, health promoters and community grid liaison staff. Each team was responsible for several areas to monitor critical populations within the grid and compile statistics on the health management of these key populations in 2022–2023. Results A total of 2050 patients with coronary artery disease, 4973 patients with hypertension, and 1621 patients with type 2 diabetes were followed up in 2022. Compared with 155,612 resident health records in 2022, the number of records increased by 140.50% in 2023. The number of patients with hypertension under health management in 2023 increased by 50.92%; patients with type 2 diabetes increased by 74.65%; and the number of coronary artery disease increased by 42.00%. After the implementation of grid management, the hospitalisation rate for patients with type 2 diabetes significantly decreased in 2023 (P < 0.05). However, the hospitalisation rate for patients with coronary artery disease and hypertension was similar in 2023 to that in 2022 (P > 0.05). Conclusion The grid-based community proactive health management model makes full use of the advantages of community resources and improves the pertinence and coverage of community health services. Moreover, it reduces hospitalisation for patients with type 2 diabetes.
First and second person forms as resources for open reference and participation in Finnish everyday
conversations
Authors: Helasvuo Marja-Liisa , Suomalainen Karita
Published: July 2024

Based on data from Finnish conversational interaction, this article explores the use of 1st and 2nd person
forms in creating deictically non-specific, open reference. We focus on the linguistic and embodied features of turns that
contain these open personal forms and examine their sequential positioning. We show that the 1st and 2nd person forms that
receive a deictically open interpretation typically occur in assessments, accounts of personal experience, and imaginary
descriptions. They function as deictic displacements, shifting the origo of the speech situation, and causing a change of
footing in the discourse roles, thus modulating the participation framework of the speech situation.
A - 18 Sport Concussion Assessment Tool-5th Edition (SCAT5) Normative Reference Values for Professional Men’s Rugby League Players
Authors: Maietta J E , Terry D A , Lakisa D R , Iverson G L , Gardner A J
Published: July 2024

Purpose

The Sport Concussion Assessment Tool-5th Edition (SCAT5) is a standardized assessment that is administered to athletes at preseason and after suspected concussion. We provide normative reference values for men’s professional National Rugby League (NRL) players.

Method

Baseline SCAT5 scores were obtained from 1005 NRL players during the 2018 and 2019 seasons (Mage = 25.9). Players self-identified whether they considered their cultural heritage or ethnicity to be “Pasifika (Pacific Islander) or Māori” (n = 243; 24.2%) or “Indigenous Australian” (n = 82; 8.2%). Those who identified as being from any other race, ethnicity, or cultural heritage were combined into a single group (n = 680; 67.7%). We provide normative values for the Standardized Assessment of Concussion (SAC), Symptom Evaluation (i.e., symptom severity and symptom number), and the Modified Balance Error Scoring System (mBESS).

Results

There were no significant differences between the cultural heritage or ethnicity groups for SAC total scores, symptom severity or number, or mBESS errors (p’s > 0.05). The median SAC score was 27 (IQR = 25–28), median symptom severity was 0 (IQR = 0–2), median symptom number was 0 (IQR = 0–1), and median mBESS error score was 3 (IQR = 1–5). SAC scores of <23 and mBESS errors >7 were uncommon in the sample while SAC scores of 26–30 and mBESS scores of 0–4 were considered within normal expectations (WNE). Reporting >4/22 symptoms and > 6/132 severity was uncommon while 0–1 symptoms and 0–1 symptom severity was WNE.

Conclusions

Normative reference values for the SCAT5 are provided for a sample of elite professional men’s rugby league players from Australia.
A - 29 Clinical Considerations for Concussion Care for Transgender Youth
Authors: Datoc A E , Mathew A S , Boucher S J , Choi D M , Ellis C , Abt J P
Published: July 2024

Purpose

Medical care for transgender youth requires a tailored approach to address their specific healthcare needs. The purpose of this study was to compare concussion patient characteristics between a population of youth who identified as transgender and their cisgender peers.

Method

Data were extracted from medical records (neurodevelopmental/psychiatric history, mechanism of injury, time between injury/evaluation, time between evaluation/recovery, and initial PCSS score) of 10 female patients selected using a stratified random sampling method (Mage = 15.0¬ ± 2.9 years) and five patients who identified as transgender with female sex assigned at birth (Mage = 14.4¬ ± 1.5 years). All patients presented to a specialty concussion clinic in 2020–2023.

Results

Patients who identified as transgender were significantly more likely to have a history of anxiety (X2[1] = 8.57, p = 0.003) and depression (X2[1] = 10.91, p < 0.001). Recovery time was significantly longer in those who identified as transgender (Mtrans = 36¬ ± 20.6 days; Mcis = 18.9¬ ± 8.6 days; p = 0.03). Days since injury to initial visit (Mtrans = 6.4¬ ± 2.4 days; Mcis = 3.8¬ ± 3.5 days; p = 0.16) and PCSS score (Mtrans = 46.8¬ ± 16.5; Mcis = 38¬ ± 26.6; p = 0.56) did not differ between groups.

Conclusions

The average recovery time for this sample of transgender youth was significantly longer than their cisgender peers. Transgender youth also reported higher rates of anxiety and depression, which are well-known to impact concussion recovery. Sensitivity to psychological distress and mental health history is crucial for overall medical care and is supported when assessing and treating concussion in transgender youth. The effects of gender transition-related treatments (i.e., hormone therapy), discomfort in gender-segregated spaces, gender dysphoria, and other minority stressors warrant further research and should also be considered in concussion care of transgender patients.
A - 30 Head-Injury Exposure and Later-in-Life Cognitive and Psychiatric Outcomes among Former Collegiate Football Players
Authors: Datoc A E , Schaffert J , Didehbani N , Doggett H , LoBue C , Cullum C M
Published: July 2024

Purpose

Current understanding of potential long-term negative cognitive and psychiatric outcomes following head-injury exposure is limited, and this study aimed to evaluate these relationships in former collegiate football players.

Method

Former collegiate football players completed the College Level Aging Athlete Study (CLEAATS) survey including playing career, concussion/medical/psychiatric history, self-reported cognitive functioning, and measures of depression, anxiety symptoms, positive affect/resilience, emotional dysregulation, and objective cognitive function. A head-injury exposure estimate (HIEE, modified from Kerr et al., 2015) was calculated to determine total sports-related head-injury exposure. Partial correlations (controlling for age and education) examined the relationship between HIEE and cognitive functioning and emotional/mood symptoms.

Results

Participants (n = 216) were 50–87 years old (M = 63.4 [8.5]), 91% White, and well-educated (bachelor’s or graduate degree = 92%). HIEE (M = 763.8 [342.9]) was not correlated with any cognitive or emotional/mood symptom measures (p’s > 0.075). Depression (r = 0.65), anxiety (r = 0.48), and emotional dysregulation indices (r = 0.50) showed moderate positive correlations with subjective cognitive symptoms. Grit (r = −0.36) and positive affect/well-being (r = −0.49) were negatively correlated with cognitive symptom reporting.

Conclusions

HIEE was not found to be related to cognitive or emotional/mood outcomes, and results suggest that current emotional/mood symptoms have greater associations with subjective cognitive symptoms. Alternatively, positive affect/resilience were found to be negatively associated with cognitive symptoms, and may serve as protective factors against cognitive complaints. These findings are consistent with previous studies that have reported associations between cognitive symptoms, psychological distress, and resilience in former athletes, highlighting the importance of considering potential impact of current emotional/mood symptoms when evaluating retired players with cognitive concerns.
A - 45 Rasch Analysis of the Brief Resilience Scale in Adolescents with Sports-Related Concussion
Authors: Sanders G D , Hynan L S , Bunt S C , Cullum C M
Published: July 2024

Purpose

Accurate measurement of latent abilities is essential for valid inference. The Brief Resilience Scale (BRS) assesses the “ability to bounce back”from stressful situations, and resilience may play a role in concussion recovery. Questions regarding the factor structure of the BRS have been explored in other populations, but evidence of its measurement quality in concussion is lacking. The present study investigated the psychometric properties of the BRS in concussed adolescents within a Rasch framework.

Method

927 participants aged 12 to 18 (M = 14.7; 50.3% female) underwent clinical evaluation within 30 days of injury in the ConTex study. The BRS contains 6 items rated on a 5-point Likert scale (Strongly Disagree to Strongly Agree), half of which are reverse scored. The Rasch Rating Scale Model was applied and item fit statistics and dimensionality were examined to assess the degree of fit of the data to the Rasch model.

Results

Item difficulties ranged −0.82 to 0.77. Item fit was adequate based on mean-square infit and outfit values. The BRS demonstrated sufficient targeting except for participants at the highest and lowest range of latent ability. Unidimensionality testing indicated the presence of a secondary dimension.

Conclusions

The BRS showed suboptimal fit with the Rasch model based on lack of unidimensionality. However, violations likely reflect item wording effects and not a substantive dimension that merits scale modification. Application of Rasch and other item response theory methodologies can enable development of more psychometrically sound and clinically informative tools for use in the context of concussion outcomes.
A - 46 Putting Together “Puzzle Pieces” of the Game: Executive Functions in Athletes with Sports-Related Concussion History
Authors: Doucette M M , Garcia-Barrera M A
Published: July 2024

Purpose

While previous quantitative research has explored the malleability of executive functions in sports, there’s a gap in understanding athletes’ descriptions and utilization of executive functions during gameplay. Understanding these processes from athletes’ perspectives is crucial for developing relevant assessments, particularly following sports-related concussion (SRC), as well as using accessible athlete-driven language to describing executive function in sports neuropsychology. Thus, our study aimed to explore how athletes deploy executive functions during games and identify the most crucial executive function components for success.

Method

19 Canadian collegiate athletes (ages 18–25; 37% female) with a history of SRC across various sports (soccer, volleyball, rugby, and basketball) were recruited. Participants completed semi-structured interviews via Zoom with a focus on identifying their executive function processes in their respective sports. Thematic analysis, following Braun and Clarke’s (2006) approach, was used to analyze the interview transcripts.

Results

We generated three themes: 1) Planning, organizing, and deciding action before actively involved in the play; 2) Problem solving when the contingencies for the pre-planned play changes; 3) Processing and evaluating performance immediately after a play.

Conclusions

These results provide nuance to our understanding of executive functions in sport by gaining insight into how athletes think while playing, information that neither tasks nor questionnaires offer. Through qualitative interviews, we discovered athletes engage in various executive processes throughout the game, including strategic planning and problem-solving. Overall, this study highlights specific executive processes employed throughout a game, which may become areas of focus for assessment, interventions, and follow-up for athletes following SRC.
A - 48 Predictors of Prolonged Recovery after Concussion in Collegiate Athletes: a LIMBIC MATARS Consortium Investigation
Authors: Smetana R M , Broshek D K , Rosenblum D J , Resch J E
Published: July 2024

Purpose

To investigate predictors of prolonged recovery after concussion in collegiate athletes.

Method

Data for this cross-sectional, retrospective chart review of collegiate athletes diagnosed with concussion (n = 1044 concussions), who were on average 20-years of age, were collected during the 2015–16 to 2019–20 athletic seasons. The majority (92% [959/1044]) of athletes achieved symptom resolution at rest and made an unrestricted return-to-sport by 23 days after injury. The remaining athletes (8% n = 85[36.5% female]), with symptoms that lasted beyond 23 days after concussion were considered to have prolonged recovery. Linear regression was used to determine predictors of prolonged recovery; times to symptom-freedom and unrestricted return-to-sport were dependent variables and variables associated with medical and psychiatric history, and some post-concussion symptoms, were independent variables.

Results

Athletes with prolonged recovery generally recovered on median (interquartile range) 32 (17) days after injury. The majority (42% [36/84]) participated in football. A self-reported history of anxiety [Β = 0.577, p = 0.01], depression [Β = 0.462, p = 0.04], a history of headache [Β = 0.84, p < 0.001], and migraine [Β = 0.761, p < 0.001] were predictors of prolonged recovery. A history of prior concussion and higher symptom burden immediately after concussion did not predict prolonged recovery (all p > 0.05).

Conclusions

Similar to related research, our findings suggest a self-reported history of psychiatric conditions, headache, and migraine associate with prolonged recovery in collegiate athletes. Our findings highlight the importance of mood symptom monitoring, early psychological intervention, and management of headache following concussion. Importantly, the majority of our sample, inclusive of collegiate athletes with prolonged recovery, recovered approximately one-month after injury.
A - 49 Predictors of Post-Concussion Anxiety In Patients without Pre-Existing Anxiety History
Authors: Patel S , Zynda A J , Miller M , Burley C , French J , Ramirez N , Guercio H , Kegel N , Bunker N , Collins M , Kontos A P
Published: July 2024

Purpose

Identify factors contributing to anxiety in individuals without a pre-existing anxiety history post-concussion.

Method

Patients (n = 264, aged 9–68) presented to a specialty concussion clinic post-concussion. They completed a clinical interview, Immediate Post-Concussion Assessment and Cognitive Test (ImPACT), Post-Concussion Symptom Scale (PCSS), Concussion Clinical Profile Screening (CP-Screen), and Vestibular/Ocular-Motor Screening (VOMS). Anxiety group was determined by a positive anxiety/mood clinical profile on CP-Screen. Independent samples t-tests and chi-square tests examined differences in demographics, medical history, and injury characteristics between groups. Univariate logistic regressions (LR) informed a follow-up forward stepwise LR to identify best predictors of post-concussion anxiety group. Receiver operating characteristic (ROC) analysis of the area under the curve (AUC) was used to identify which predictors retained from the LR model best-discriminated anxiety status. Statistical significance was set a priori at p < 0.05.

Results

Results of forward stepwise LR identifying factors contributing to post-concussion anxiety were significant (p < 0.001) and accounted for 19% of the variance. The model accurately classified 82.2% of patients, with non-Sport Related Concussion (SRC) (OR = 2.94, 95%CI, 1.45–1.5.98, p = 0.003), history of ADHD/LD (OR = 2.85, 95%CI, 1.21–6.71, p = 0.02), positive vestibular profile (OR = 2.14, 95%CI, 1.06–4.33, p = 0.03), and days to first clinic visit (OR = 1.01, 95%CI, 1.01–1.015, p = 0.003) as significant predictors. ROC analysis of the AUC of this 4-factor model discriminated post-concussion anxiety from no anxiety (AUC, 0.77, 95%CI, 0.71–0.85, p < 0.001).

Conclusions

Findings suggest that non-SRC, ADHD/LD history, positive vestibular profile, and delayed clinic visit, may contribute to post-concussion anxiety among patients without prior anxiety history. These predictors may guide clinicians in tailoring interventions to optimize recovery outcomes.
A - 53 Age of First Exposure to Football and Later-Life Health Issues in Community-Dwelling Adults
Authors: Rigney G , Dugan J , Bishay A , Jonzzon S , Jo J , Williams K , Zuckerman S , Terry D
Published: July 2024

Purpose

This study assessed whether age of first exposure (AFE) to football was associated with later-life psychiatric and neurobehavioral symptoms, cognitive difficulties, and general health problems in a cohort of former amateur football players.

Method

A cross-sectional survey study of men with a history of amateur football exposure was conducted using the ResearchMatch online platform. Independent variables included demographics, number of lifetime concussions, AFE to football (dichotomized as AFE < 12 years vs. AFE ≥ 12 years), and total years of football participation. Main outcomes included current depressive (Patient Health Questionnaire-9), anxiety (Generalized Anxiety Disorders-7), cognitive (British Columbia Cognitive Complaints Inventory), and neurobehavioral symptoms (Neurobehavioral Symptom Inventory). T-tests (AFE < 12 vs. AFE ≥ 12) and multivariable regressions assessed for associations between AFE and outcome variables, adjusting for age, number of prior concussions, and years of football exposure.

Results

A total of 107 male participants (mean age = 60.6 ± 15.1 years) reported an average of 4.2 ± 2.7 years of exposure to amateur football, with 41 participants reporting AFE < 12 (38.3%). In multivariable analyses, AFE < 12 was not a significant predictor of depressive (B = 0.51, SE = 1.25, p = 0.682), anxiety (B = 0.09, SE = 0.95, p = 0.926), cognitive (B = -0.65, SE = 0.77, p = 0.403), or neurobehavioral symptom scores (B = -0.56, SE = 2.93, p = 0.850). However, having more prior concussions were associated with worse depressive (B = 0.44, SE = 0.10, p < 0.001), anxiety (B = 0.33, SE = 0.07, p < 0.001), cognitive (B = 0.26, SE = 0.06, p < 0.001), and neurobehavioral symptoms (B = 1.04, SE = 0.23, p < 0.001).

Conclusions

AFE to football was not associated with adverse psychiatric, cognitive, or neurobehavioral difficulties. However, these outcomes were associated with a greater number of lifetime concussions.
A Bibliometric Analysis of the Top 100 Papers on Gluteal Augmentation
Authors: Daneshi Kian , Mansour Hamid Reza Khademi , Pacheco-Barrios Niels , Asaju Ayobami , Pérez Pachon Mauricio , Hoyos Alfredo , Khajuria Ankur
Published: July 2024

Background

Gluteoplasty or gluteal augmentation is a popular cosmetic procedure that is used to improve the volume, shape, and contour of the buttocks.

Objectives

This bibliometric analysis aims to characterize emerging research trends and to assess the methodological quality of the highest impact gluteoplasty research.

Methods

The 100 most-cited publications in gluteoplasty were identified on Web of Science, across all available journal years (from Inception to August 2023). Study details, including the citation count, main content focus, and outcome measures, were extracted and tabulated from each publication. Oxford Centre for Evidence Based Medicine level of evidence (LOE) of each study was assessed.

Results

The 100 most-cited publications regarding gluteoplasty were cited by a total of 2375 publications. Citations per publication ranged from 5 to 176 (mean 23.75 ± 25.86), with the highest-cited study being authored by Simonacci, discussing autologous fat grafting (n = 176). Most publications were LOE 5 (n = 55), representative of the large number of case series and reports. The number of publications for LOE 1, 2, 3, and 4 was 1, 9, 13, and 22, respectively. The main content focus was “surgical technique” in 38 publications, followed by “outcomes” (n = 34) and “risk factors/prognosis” (n = 10). Patient-reported outcome measures (PROMs) were used in 20 publications, and 33 publications reported aesthetic outcome measures.

Conclusions

This analysis demonstrates a need for improvement in research methodologies regarding gluteoplasty research. This advancement would be facilitated by robust, high-quality research through randomized control trials and multicenter studies, as well as the further development of validated PROMs for gluteoplasty.

Level of Evidence: 2