bluuebunny/crossref_metadata_2025 huggingface dataset:
РОЛЬ НАУКОВОЇ Й ЕКСПЕРИМЕНТАЛЬНО-ДОСЛІДНИЦЬКОЇ ДІЯЛЬНОСТІ М. О. ТЮЛЕНЄВА ДЛЯ УКРАЇНСЬКОГО СОЦІУМУ В 30-ті – 60-ті рр. ХХ ст.
Authors: Шульга Наталія
Published: March 2021

У статті охарактеризовано діяльність вітчизняного агромеліоратора, член-кореспондента АН УРСР, професора Миколи Олександровича Тюленєва (1889-1969 рр.) в Українському науково-дослідному інституті гідротехніки і меліорації протягом 30-х – 60-х рр. ХХ ст., а також проаналізовано результати його експериментально-дослідницьких робіт у галузі теорії, методології та практики агромеліоративної дослідної справи.
Авторкою використовувалися історико-генетичний, історико-хронологічний, проблемний, історико-порівняльний, персонологічний та біографічний методи. Крім того, застосовано методи систематизації та джерелознавчої критики.
Встановлено, що протягом роботи в УНДІГіМ М. О. Тюленєв проводив дослідження щодо підготовки й обробітку ґрунту, удобрення болотних ґрунтів (кислих, нейтральних і лужних), ведення рільництва, вирощування просапних і технічних культур (у тому числі цукрового буряка), городніх та ягідних культур, сіяних луків і пасовищ, їх поверхневого покращення, боротьби з бур’янами та використання удобрення на мінеральних ґрунтах. Учений керував осушувальними меліораціями під методичним координуванням УНДІГіМ. Протягом 1944-1947 рр. М. О. Тюленєв очолював відділ осушення НДІ, активно долучившись до відновлення опорної мережі інституту після звільнення окупованих територій від німців. Вчений здійснював наукове керівництво двома науково-дослідними темами: Меліоративно-гідрологічна характеристика малих річок УРСР як основа розробки проблеми комплексного використання малих річок; Конструкція і розрахунки каналоочисників для мілкої осушувальної системи.
З’ясовано, що у 1950-х рр. М. О. Тюленєв працював над вивченням можливостей і перспектив раціонального використання осушених торфових ґрунтів, насамперед, під луки і пасовища для створення міцної кормової бази. Стосовно галузі механізації меліоративних робіт поряд із виконанням завдань з будівництва й очищення каналів, питань дощування у творчості М. О. Тюленєва вирішення знайшла і механізація кротодренажних робіт, яку він проводив разом з С. І. Рудич. Ученого по праву називають класиком агромеліоративної дослідної справи радянського періоду.
ФІЛОСОФСЬКІ ТА СУСПІЛЬНО-ПОЛІТИЧНІ ПОГЛЯДИ САЇДА НУРСІ
Authors: Яценко Богдан
Published: March 2021

С. Нурсі – відомий філософ та релігійний діяч І пол. ХХ ст. Його філософські та суспільно-політичні ідей були сформовані під впливом стагнації, внутрішніх та зовнішніх проблем Османської імперії, що доживала свої останні десятиріччя. С. Нурсі діяв в часи, коли могутня в минулому Османська імперія преживала гостру суспільну кризу. Перша Світова війна відкрила очі всього мусульманського світу на реальну могутність Європейської індустріальної машини. Логічно, що це викликало хвилю обурення старими порядками, намагання відійти від своїх споконвічних традицій. Але зараз ми чудово знаємо, що дивіз: «Весь мир насилья мы разрушим. До основанья, а затем. Мы наш, мы новый мир построим» не працює так, як хотіли б того радикальні реформатори. Пік суспільно-політичної активності Саїда Нурсі прийшовся на першу чверть ХХ ст., часи тріумфу народних сподівань на рішучі зміни в країні, які так і не відбулися. Згідно із власною філософією, навіть у часи тотальної бюрократії та погіршення становища у Османській імперії, він добився дозволу та кошт на впровадження своїх освітянських ідей. Будучи дійсно мудрою людиною, Саїд Нурсі вважав, що від старих порядків не можна відходить, але треба змінювати їх відповідно до сучасних потреб суспільства.
Analysis of the current legal status of land use
Authors:   Land Management Institute of the National Academy of Sciences of Ukraine, Kharytonenko R. , Kolisnyk G. ,   National University of Life and Environmental Sciences of Ukraine
Published: March 2021

The analysis of the state of land use on the example of institutions and enterprises of the National Academy of Agrarian Sciences of Ukraine in the context of studying the compliance of the State Land Cadastre (SLC), the State Register of Real Rights (SRRR) and title documents on land use rights. The necessity of conducting analysis and making managerial decisions as a supplement to the land inventory or a separate management to solve problems that are not solved by developing land management documentation (technical inventory documentation) is substantiated. Problems in the legal status, which were identified with the help of data from the SLC, SRRR, as well as the source information of the title documents, are highlighted. It is proposed to divide them into typical, which are inherent in the majority of land uses of NAAS and exceptional, which have not become widespread. The classification of the revealed problems during the analysis of a modern condition of use of the earths of establishments and the enterprises of NAAS is presented and generalized. Ways to solve the identified problems on the example of land institutions and enterprises of NAAS, which are the need for land inventory, as the main tools for land management, as well as consistency of information SLC, SRRR, return of illegally allotted land to third parties.
Review of the genera of the family Sagittidae with separation of a new subfamily and description of a new species of the genus Sagitta from the Sea of Japan (Chaetognatha)
Authors: Kassatkina A.P.
Published: March 2021

Diagnoses and lists of species are given for the genera of Sagittidae. A new subfamily Flaccisagittinae is established for the genera Flaccisagitta, Pseudosagitta, Accedosagitta, and Abosagitta. A new species, Sagitta sceptrum sp. n., is described from the Sea of Japan.
Evaluation of the Anti-inflammatory and Analgesic Activity
of the Ethanolic Extract Arial Parts of Calendula suffruticosa subsp. Suffruticosa Vahl
Authors: Sofiane I. , Azin K. , Seridi R.
Published: March 2021

The current study aims to evaluate the toxicity and the pharmacological activities of a spontaneous, medicinal and aromatic plant of the North-east of Algeria. Calendula suffruticosa subsp. suffruticosa Vahl. (Asteraceae) is widely used in traditional medicine to treat various diseases including inflammation, duodenal ulcers, burns and skin diseases. The anti-inflammatory activity of the ethanolic extract was evaluated by the inflammatory edema test induced by carrageenan in mice. And the analgesic activity has been determined in a model of pain induced by acetic acid. The diclofenac and acetylsalicylic acid are used as reference drugs. The toxicological study of the ethanolic extract revealed that the LD50 of this extract is greater than 1,000 mg/kg of body weight. The ethanolic extract at the dose 200 and 400 mg/kg administered orally and possesses a significant anti-inflammatory activity (test of Anova). The results of the analgesic activity also show the strong effect of the extract tested against chemical pain. This extract at a dose of 400 mg/kg, has analgesic activity greater to that of acetylsalicylic acid in the dose of 100 mg/kg, with a percentage inhibition of 81.13 ± 1.09%. These results confirm the anti-inflammatory and analgesic properties of Calendula suffruticosa subsp. suffruticosa Vahl., which are mainly due to the phytochemical composition of the extract studied.
Official Development Assistance as an Aspect of the Australia-China Competition in the South Pacific
Authors:   Institute of oriental studies, Russian academy of science (MOSCOW), Garin Artyom A.
Published: March 2021

Due to China's increasing involvement in South Pacific, there is a growing interest on the part of the middle and great powers in providing the Pacific island States with an increasing amount of material assistance. With its unique geographical location, as well as numerous initiatives in the humanitarian, trade, economic and defence areas, Australia's influence is reinforced by its status as the major ODA source in Oceania. At the same time, despite Australia's clear advantage in providing ODA to South Pacific states, the region is attracting an increasing number of countries aimed at providing ODA to South Pacific countries, especially China.
"Beautiful women suffer unhappy fates"? History of beauty pageants in Vietnam. Part II. Modern beauty contests
Authors:   Institute of Asian and African Studies, Lomonosov Moscow State University. Russia, Moscow, Syunnerberg Maxim A.
Published: March 2021

In the second part of the article, the author examines the influence of new trends in social thought of the 20th century on the interpretation of the concept of “beauty” and the possibilities of women to realize themselves through beauty. We will also present the collected information on beauty contests held in the country. In accordance with the idea in the title, special attention is paid to the fate of some of the winners.
Yoko Kato: the silent warrior of neurosurgery
Authors: Shah Abhidha
Published: March 2021

The presence of women in neurosurgery is slowly but surely gaining momentum as many aspiring young female medical residents are being enticed by this fascinating branch. History is rife with the struggles of pioneering women who entered the neurosurgical profession against all odds, formed a firm foothold, and built a legacy for generations to emulate. Prof. Yoko Kato has spent her entire lifetime in the service of neurosurgery and taking it to the remotest corners of the world. Her persistence and conviction have made her one of the most admired neurosurgeons in the world and the most loved neurosurgeon for those in the less privileged countries. She has inspired and trained an entire generation of neurosurgeons. Her contributions will always be a glorious chapter in the world book of neurosurgery.
History of Women in Neurosurgery (WINS)
Authors: Hdeib Alia , Elder Theresa , Krivosheya Daria , Ojukwu Disep I. , Wijesekera Olindi , Defta Dana , Ben-Haim Sharona , Benzil Deborah L.
Published: March 2021

In 2020, the Women in Neurosurgery (WINS) organization, a joint section of the AANS and Congress of Neurological Surgeons, celebrated 30 years since its inception. In this paper, the authors explore the history of WINS from its beginnings through its evolution over the past three decades. The achievements of the group are highlighted, as well as the broader achievements of the women in the neurosurgical community over this time period.
The progression of diversity: Black women in neurosurgery
Authors: Bryant Jean-Paul , Nwokoye Diana I. , Cox MaKayla F. , Mbabuike Nnenna S.
Published: March 2021

While diversity in organized medicine has undoubtedly improved, a disparity remains in the racial and gender makeup of its constituents. This disparity is not distributed equally among all specialties of practice. The surgical subspecialties exemplify this phenomenon by having large gaps between the number of women and racial/ethnic minorities compared to their majority counterparts. Pertaining to neurosurgery in the US, this gap is substantial, with women reaching minority status only within the last 2 years. Among international women in neurosurgery, Black women are even further underrepresented despite efforts in recent years to close the gender gap. The reason for this disparity is likely multifactorial, as Black women demonstrate a unique intersectionality as a minority in regard to both race and gender. In this study, the authors provide historical context for the current state of diversity in neurosurgery and the global strides made by Black women within the field. The authors report recurrent themes in the experiences of Black female neurosurgery attendings and residents as revealed through personal interviews. Furthermore, they examine factors that contribute to the disproportionate representation of Black women in neurosurgery.
Resiliency of a perpetual optimist: neurosurgeon Dr. Linda Liau
Authors: Thum Jasmine A.
Published: March 2021

It is not possible to capture all the depth that composes Dr. Linda Liau: chair of the Neurosurgery Department at the University of California, Los Angeles; second woman to chair a neurosurgery program in the United States; first woman to chair the American Board of Neurological Surgery; first woman president of the Western Neurosurgical Society; and one of only a handful of neurosurgeons elected to the National Academy of Medicine. Her childhood and family history alone could fascinate several chapters of her life’s biography. Nonetheless, this brief biography hopes to capture the challenges, triumphs, cultural norms, and spirit that have shaped Dr. Liau’s experience as a successful leader, scientist, and neurosurgeon. This is a rare story. It describes the rise of not only an immigrant within neurosurgery—not unlike other giants in the field, Drs. Robert Spetzler, Jacques Marcos, Ossama Al-Mefty, and a handful of other contemporaries—but also another type of minority in neurosurgery: a woman.
Women in neurosurgery: where does the United Kingdom stand?
Authors: Amarouche Meriem , Uberti Micaela , Evans Gwenllian Y. H. R. , Singh Navneet
Published: March 2021

Despite over half of medical students in the United Kingdom (UK) being female, women represent only a small proportion of the workforce in the traditional “male” specialties, including neurosurgery. There is increasing global attention to and awareness of gender discrimination in the workplace across several industries, including health care. The authors set out to explore the opinions and attitudes of UK neurosurgeons and neurosurgery trainees on gender issues via a large-scale national survey. The results highlight key perceptions and gaps in mentorship and leadership and provide ideas for change. This should be used as a foundation to delve deeper and to address specific questions in order to achieve a fairer, more meritocratic environment in which neurosurgeons can thrive.
Cross-sectional analysis of women in neurosurgery: a Canadian perspective
Authors: Veilleux Catherine , Samuel Nardin , Yan Han , Bass Victoria , Al-Shahrani Rabab , Mansur Ann , Rutka James T. , Zadeh Gelareh , Hodaie Mojgan , Milot Geneviève
Published: March 2021

OBJECTIVE

Although the past decades have seen a steady increase of women in medicine in general, women continue to represent a minority of the physician-training staff and workforce in neurosurgery in Canada and worldwide. As such, the aim of this study was to analyze the experiences of women faculty practicing neurosurgery across Canada to better understand and address the factors contributing to this disparity.

METHODS

A historical, cross-sectional, and mixed-method analysis of survey responses was performed using survey results obtained from women attending neurosurgeons across Canada. A web-based survey platform was utilized to collect responses. Quantitative analyses were performed on the responses from the study questionnaire, including summary and comparative statistics. Qualitative analyses of free-text responses were performed using axial and open coding.

RESULTS

A total of 19 of 31 respondents (61.3%) completed the survey. Positive enabling factors for career success included supportive colleagues and work environment (52.6%); academic accomplishments, including publications and advanced degrees (36.8%); and advanced fellowship training (47.4%). Perceived barriers reported included inequalities with regard to career advancement opportunities (57.8%), conflicting professional and personal interests (57.8%), and lack of mentorship (36.8%). Quantitative analyses demonstrated emerging themes of an increased need for women mentors as well as support and recognition of the contributions to career advancement of personal and family-related factors.

CONCLUSIONS

This study represents, to the authors’ knowledge, the first analysis of factors influencing career success and satisfaction in women neurosurgeons across Canada. This study highlights several key factors contributing to the low representation of women in neurosurgery and identifies specific actionable items that can be addressed by training programs and institutions. In particular, female mentorship, opportunities for career advancement, and increased recognition and integration of personal and professional roles were highlighted as areas for future intervention. These findings will provide a framework for addressing these factors and improving the recruitment and retention of females in this specialty.
A minimally invasive lateral approach with CT navigation for open biopsy and diagnosis of Nocardia nova L4–5 discitis osteomyelitis: illustrative case
Authors: Zheng Bryan , Abdulrazeq Hael , Leary Owen P. , Gokaslan Ziya L. , Oyelese Adetokunbo A. , Fridley Jared S. , Camara-Quintana Joaquin Q.
Published: March 2021

BACKGROUND

Lumbar spine osteomyelitis can be refractory to conventional techniques for identifying a causal organism. In cases in which a protracted antibiotic regimen is indicated, obtaining a conclusive yield on biopsy is particularly important. Although lateral transpsoas approaches and intraoperative computed tomography (CT) navigation are well documented as techniques used for spinal arthrodesis, their utility in vertebral biopsy has yet to be reported in any capacity.

OBSERVATIONS

In a 44-year-old male patient with a history of Nocardia bacteremia, CT-guided biopsy failed to confirm the microbiology of an L4–5 discitis osteomyelitis. The patient underwent a minimally invasive open biopsy in which a lateral approach with intraoperative guidance was used to access the infected disc space retroperitoneally. A thin film was obtained and cultured Nocardia nova, and the patient was treated accordingly with a long course of trimethoprim-sulfamethoxazole.

LESSONS

The combination of a lateral transpsoas approach with intraoperative navigation is a valuable technique for obtaining positive yield in cases of discitis osteomyelitis of the lumbar spine refractory to CT-guided biopsy.
PROSPECTS FOR THE DEVELOPMENT OF THE NORTHERN SEA ROUTE. NORTHERN SEA TRANSIT CORRIDOR
Authors:   The Admiral Makarov State University of Maritime and Inland Shipping, Tregub М. А. , Iaroshenko-Sokolovskaia К. А. ,   The Admiral Makarov State University of Maritime and Inland Shipping
Published: March 2021

The article presents a comparative analysis of international maritime transport routes – the Northern Sea Route (NSR) and the Southern Sea Route (SMP). The article analyzes the competitive advantages and disadvantages of the Northern Sea Route in comparison with the Southern Sea Route. Based on the study of the main logistics characteristics of sea arteries: length, climate, economic risks in the northern and southern directions of sea cargo transportation, a conclusion is made about the potential of the Northern Sea Route. The possibility of redistributing part of the international cargo transportation currently carried out along the Southern Sea Route to this direction is being considered.
Bardaiṣan’s Doctrine on Fate
Authors: Денисюк Сергий
Published: March 2021

В статье приводятся краткие биографические сведения о сирийском писателе Бардесане (154-222/223 гг.), а также затрагивается проблема авторства «Книги законов стран». В основной части определяется значение ключевых для Бардесана понятий: «судьба», «природа» и «свобода», которые затем подробно рассматриваются в контексте его учения. В заключение статьи определяется значимость богословской доктрины Бардесана для антифаталистической и антиастрологической полемики и даётся православная оценка мировоззрению сирийского писателя.

This article provides short biographic information about Bardaiṣan (154- 222/223) and discusses the problem of authorship of the work «The Book of the Laws of Countries». In the main part the A. considers the value of key concepts of Bardaiṣan - fate, nature and freedom, which then in detail are considered in the context of Bardaiṣan’s doctrine. In the conclusion of the article the importance of the doctrine of Bardaiṣan anti-fatalistic and antiastrological polemic is defined and an Orthodox assessment of the ideology of the Syrian writer is given.
Review of: Chronicle of the life and works of St. Theophanes the Recluse Vyshensky. I volume. Moscow: Publishing Council of the Russian Orthodox Church, 2016. 928 p.; II vol. Moscow: Publishing Council of the Russian Orthodox Church, 2019. 680 p. ISBN 978-5-558-1 (общий) I том. ISBN 978-5-560-4 II том. ISBN 978-5-88017-760-8
Authors: Каширина Варвара Викторовна
Published: March 2021

С жизнью и творчеством крупнейшего русского богослова и духовного писателя второй половины XIX в. святителя Феофана Затворника читатель может теперь подробно познакомиться в первых двух томах Летописи его жизни и творчества. Среди отечественных богословов сегодня вряд ли можно назвать какое-нибудь другое имя, кому в последнее время было посвящено столько исследований. Ежегодные Феофановские чтения, конференции и семинары 1 свидетельствуют о всё возрастающем интересе к личности и творениям святителя. Как отметил в Предисловии к первому тому Святейший Патриарх Московский и всея Руси Кирилл, «духовное наследие святителя Феофана представляется и сегодня весьма актуальным для верующего человека. Принципы духовной жизни, сформулированные в трудах святителя “Путь ко спасению”, “Начертание христианского нравоучения”, “Письма о христианской жизни” служат руководством для тысяч и тысяч содевающих свое спасение.

The life and work of the greatest Russian theologian and spiritual writer of the second half of the nineteenth century, St Theophan the Recluse, is now available to the reader in the first two volumes of the Annals of his Life and Work. Among Russian theologians today one can hardly name any other name to whom so much research has been devoted lately. Theophanes' annual readings, conferences, and seminars 1 testify to a growing interest in the personality and writings of the saint. As His Holiness Patriarch Kirill of Moscow and All Russia noted in the Preface to the first volume, "The spiritual legacy of St Theophanes is still very relevant for the believer. The principles of spiritual life, formulated in his works The Way to Salvation, The Outline of Christian Morals, and Letters on the Christian Life, serve as a guide for thousands and thousands who seek salvation.
LEXICOGRAPHIC SOURCES IN THE PERIOD OF NEW POLAND
Authors:   Khmelnitskyi National University, TORCHYNSKA N.
Published: March 2021

In the article the surnames of the village Bozhykivtsi are analyzes. At the same time, it is indicated that today significant successes have been in general achieved in the study of anthroponymic heritage of Ukraine, in particular, the surnames of Hutsul region (B. B. Blyzniuk), Boykivshchyna (G. E. Buchko), Lubenshchyna (L. O. Kravchenko), Opillya (H. D. Panchuk), Upper Transnistria (I. D. Farion), etc. The purpose of our research is to analyze the anthroponyms of the village of Bozhykivtsi and to carry out their lexical-semantic and word-forming characteristics on three time periods (1855, 1946 – 1949 and 1986 – 1990), to show the changes in the composition on the basis of a comparative analysis of the surnames. The funds of archives were the sources of the study of surnames, as a result of which a card index was compiled. The material for the study was 649 surnames. The word-forming-structural analysis of surnames of the village of Bozhykivtsi allowed to distinguish morphological and lexical-semantic formations. Anthropo unitst of the village Bozhikivtsi that has been formed by the lexico-semantic way are motivated by: 1) onymic vocabulary: a) surname, corresponding to the personal name; b) surnames corresponding to toponyms; 2) appellate vocabulary: a) surnames related to nouns: non-derivatives and derivatives; b) surnames related to composites; c) surnames related to adjectives. The morphological way of creating anthroponyms is represented only by suffixation. Surnames are formed with the help of patronymics (-евич / -ович, -ич), polyfunctional (-енк-о, -ук / -’ук, -чук, -ик, -ськ-ий / -цьк-ий, -ак / -’ак, -чак, -к-о, -ець, -ан/-’ан, -унь, -л-о, -ій, -ок, -ач), possessive (-ов / -ев / -єв / -ів , -ин / -ін) formants. Thus, it has been established that 44% of the surnames of the first period are preserved in the third time period, so 56% of anthroponyms are new, which is primarily due to the migration of the inhabitants. It was found that at all stages, more names motivated by appeals, less – proper names. Anthroponyms with uncertaine semantics consist 2-3%. Lexical-semantic formations dominated in the first time period, and the morphological one in the second and third periods. The most productive forms wereук/-’ук/-чук, -ськ/-цьк.
LEXICAL STYLISTIC AND PHONETIC FEATURES OF THE AUSTRALIAN ENGLISH LANGUAGE IN THE CONTEXT OF LINGUISTIC COUNTRY STUDIES
Authors:   Khmelnitskyi National University, MARTYNYUK O.
Published: March 2021

The article deals with the process of formation and development of the Australian English language, characterizes its present-day lexical, stylistic and phonetic features. It has been found out that the Australian variety of the English language was formed as a result of interaction and development of dialects, colloquialisms, slang, through which the first settlers and emigrants from Great Britain, the United States and other countries of the world communicated. As far as everyday vocabulary is concerned, Australian English shares words and phrases with both British and American English, but also has some terminology of its own. Some elements of Aboriginal languages were incorporated into Australian English, mainly as names for the indigenous flora and fauna, as well as extensive borrowings for place names. Australian English has its own characteristic lexical and stylistic features such as a small number of words from Aboriginal languages; formation of new lexical units by extending pre-existing meanings of words; novel compounds; novel fixed phrases; coinage of lexical units; application of vocabulary from British regional dialects; unique means of imagery (metaphors and similes) that reflect the national Australian authenticity. The most common ways of forming Australian slang vocabulary have been described. A unique set of diminutive forms and abbreviations in Australian English has been exemplified. Australianisms have been defined as words or phrases that either originated or acquired new meanings in Australia and are widely used in everyday Australian English. Australians have a distinct accent, which varies between social classes and is sometimes claimed to vary from state to state, although this is disputed. The difference between the three major Australian accents (Broad Australian, General Australian, and Cultivated Australian) has been highlighted. Cultivated Australian is considered to be closely approaching British Received Pronunciation and Broad Australian – vigorously exhibiting distinctive regional features.
THE IMPACT OF MEDIA PROMOTION IN PUBLIC HEALTH TOWARDS SOCIETY’S STIGMA ON HIV/AIDS SURVIVORS AT KRAJAN SUB – VILLAGE, BANJARSARI WETAN VILLAGE, DAGANGAN DISTRICT, MADIUN REGENCY
Authors: 'Izzat Muhammad Anwarul , Ratnawati Riska , Marsanti Avicena Sakufa
Published: March 2021

The 2018 national prevalence of HIV/AIDSwas 301.959 cases. The 2016 East Java had an HIV/AIDS prevalence was 6.315 cases,the prevalence of HIV/AIDS in Madiun of 2002-2009 amounted to 343 cases. The prevalence in Dagangan was 46 cases. The HIV/AIDS cases in Dagangan was small, but peoples stigma on HIV/AIDS fall in high category, one in the BanjarsariWetan village. Therefore, the purpose of this studied to identify the impact of Public Health Promotion had on peoples stigma in HIV/AIDS sufferers. The kind of this research used experimental methods of epidemiology, and used pre-experimental design (one group pretest and posttest design). The population of this studied about 1,326 people and the numbers of samples were 171 respondents. The results of pre-test and post -test studies, means 96 respondents have dropped the stigma on HIV/AIDS sufferers from pre test to posttest scores. The result of the ties' value was 59, so there is a similar value between the pre test and the post test for those who develop the stigma on HIV/AIDS. Based on wilcoxon's test analysis, the value of p=0,000 can be concluded that a significant impact can be noted between the stigma on society's intervention and the promotion of health care for those with HIV/AIDS in pre-test and post-test values. Increased tools and information infrastructure to increase public knowledge about HIV/AIDS are urgently needed.
The Effects of Counseling and Drug Information Services by Pharmacist to Medication Adherence and Therapy Outcomes on Sciatica Patients at Dr. Suyoto Hospital, Jakarta
Authors: Ariyani Farida , Sarnianto Prih , Andayani Nurita
Published: March 2021

People suffered from sciatica, pain along the sciatic nerve, require therapy up to 4 months or longer to achieve controlled-pain. The main treatment for sciatica is physiotherapy; medication is only secondary therapy. This quasi-experimental study aimed to investigate the effects of counseling and drug information services (DIS) by pharmacist on medication adherence and duration of therapy. In the study conducted in March‒July 2018, 128 ambulatory sciatica patients newly diagnosed at Dr. Suyoto Hospital, Jakarta, were divided randomly into two groups, each of 64 patients. The intervention group was given counseling and DIS by clinical pharmacists (3 times with interval of 4 weeks) as well as brochures. Primary data on medication adherence were obtained prospectively through interviews using a validated questionnaire, before the intervention and 4 weeks after the last counseling and DIS by clinical pharmacists. Secondary data (up to 16 weeks), including pain scores, were obtained from medical records and the patient administrative data. The results showed that sociodemographic characteristics as well as distribution of initial adherence and initial pain levels of the two groups were not significantly different (Mann-Whitney test, p>0.05). After the last intervention, the proportion of patients with high-adherence in the intervention group (12.5%) was higher than in the control group (6.3%), as was the proportion of patient achieved controlled-pain (84.4% versus 76.6%).  The results of survival analysis showed that the duration of treatment by which 50% of patients achieved controlled-pain (median survival) was significantly shorter in the intervention group (85 days) than in the control group (92 days), while the probability of achieving controlled-pain (hazard ratio) in the intervention group was 1.7 times of that in the control group. In conclusion, counseling and DIS by pharmacist can improve the effectiveness of sciatica treatment, although the main therapy for the nerve pain is not medication.
The choice of method of introduction of active substances into the basis of the cream for the treatment of acne and demodecosis
Authors: Koval A. S.
Published: March 2021

Among dermatological diseases demodicosis and acne occupy a very important place. The incidence of demodicosis is more than 5% and ranks seventh in frequency among dermatological diseases. It is known that demodicosis can turn into acne.

Treatment of demodicosis and acne does not lose its relevance. This medical problem can be solved through the development of the composition and technology of a soft drug of complex action with the content of active substances used to treat these diseases. Since in dermatology for external use the optimal soft medicines is a cream (taking into account the medical and biological requirements for the drug for the treatment of this disease), we have developed the composition of the base, which is the rheological properties of the cream.

The aim of the work is to substantiate the optimal method of introducing active pharmaceutical ingredients into the basis of a soft medicines.

Materials and research methods – metronidazole, benzyl benzoate, benzoyl peroxide, emulsion base. When choosing the optimal method of introduction of active pharmaceutical ingredients to the base used pharmaco-technological research methods (homogeneity of the content of API in the base). Used a microscope with a photoresist (microscope – OLYMPUS BX-41, photoresist – OLYMPUS U-CMAD3, Japan).

Active pharmaceutical ingredients was added to the base in the form of a suspension with glycerol. According to previous studies, we found that propylene glycol and polyethylene oxide were used to obtain the suspension. Studies have shown that in the process of storage for 6 months at room temperature there is a stratification of the base, in order to improve the stability of the composition of the developed cream, we introduced glycerin.

Experimental studies have shown that active pharmaceutical ingredients in the form of a suspension must be introduced into the base alternately: a suspension of metronidazole, a suspension of benzoyl peroxide. After bringing the mass to homogeneity, benzyl benzoate was finally introduced. We studied 8 samples with different sequence of administration of active substances in suspension with glycerol, sample № 2 in the study showed the best results of homogeneity of the suspension, so this method we used in further studies.

Experimental studies have established the procedure for the introduction of active pharmaceutical ingredients in the form of a suspension to the base: a suspension of metronidazole, a suspension of benzoyl peroxide and, last but not least, benzyl benzoate. The results of the research make it possible to develop a rational technology for the production (manufacture) of a treated soft medicines with metronidazole, benzyl benzoate and benzoyl peroxide for dermatology.
Visual motor integration: generation, development, and its importance for ophthalmology
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Egorov E.A. , Romanova T.B. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Rybakova E.G. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: March 2021

Visual motor coordination (VMC) is the coordination of the motions and their elements resulting from the collaborative and simultaneous activity of the visual and motor analyzers required for daily activities, sports, and professional activities. The development of VMI begins in the early childhood and proceeds throughout human life being the most active within the first 10 years. VMC is a part of visual motor integration (VMI) defined as a complex combination of skills to correctly execute the movements of arms, legs, and body. The potential causes of impaired VMI are arrested development due to living conditions, organization of teaching, individual developmental or health characteristics; nervous system diseases (i.e., head injuries, cerebrovascular disorders, intoxication etc.); and, in particular, visual impairments. Since the quality of visual functions is an important component of good VMC, its generation and development require adequate vision correction. It was demonstrated that the degree of myopia may affect school performance in the areas requiring VMI. Optical correction of ametropias improves VMC. This should be considered when managing patients (in particular, children) with refractive errors. Keywords: visual motor coordination, visual and motor analyzers, visual functions, optical correction, micro-level orientation, fine motor skills, synchronization. For citation: Egorov E.A., Romanova T.B., Rybakova E.G. Visual motor integration: generation, development, and its importance for ophthalmology. Russian Journal of Clinical Ophthalmology. 2021;21(1):14–17. DOI: 10.32364/2311-7729-2021-21-1-14-17.
ANALISIS PENGARUH KUALITAS PELAYANAN TELLER TERHADAP KEPUASAN ANGGOTA PADA BMT POLIDANA POLITEKNIK NEGERI SEMARANG
Authors: Sunindyo Aris
Published: March 2021

This study aims to examine the quality of teller service which consists of tangibles, reliability, responsiveness, assurance, and empathy of member satisfaction by saving at Baitul Maal Wat Tamwil (BMT) Polidana Semarang State Polytechnic. The data used are primary data in the form of questionnaires' distribution to BMT members. The data used are primary data which are distributed through questionnaires to BMT members. This study used 100 members of the BMT Polidana as a sample. The data analysis tool used multiple regression analysis with SPSS 21. The results showed that tangibles, reliability, responsiveness and assurance had a significant effect on member satisfaction in saving at BMT Polidana State Polytechnic Semarang while empathy (empathy) does not have a significant effect on member satisfaction in saving at BMT Polidana Semarang State Polytechnic
A Geospatial Approach to Enhance Point of the Interest and Tourism Potential Centers in Parner Tehsil in Maharashtra, India
Authors: Salunke Vasudev S. , Lagad Santosh J. , Bhagat Ravindra S. , Kudnar Nanabhau S.
Published: March 2021

This study aims to identify geographical points of interest and tourism potential in Parner tehsil of Ahmednagar District of Maharashtra and to highlight the attractive tourist destinations and religious places in the region. To the introduced exact situation and importance of many wonderful, useful distinctive places and geographical point of interest in Parner tehsil. This paper is descriptive in nature and qualitative study based on empirical observations. This study based on primary and secondary data. All natural geographical, historical and cultural tourist centers were visited during study period. Parner tehsil is enriched of geographical, historical, and cultural tourism aspects. Suitable maps were prepared with the help of QGIS and ARC MAP software’s for the ease of tourists. Tourist attractions in the tehsil as is, natural beauty, potholes, caves, temples, ideal village, industries, festivals etc. Even though Nighoj potholes and Vadgaon Darya caves are famous geographical destinations but other places are neglected by tourism industry experts. This paper will also become much helpful for planner, tourists, historians, geographers and archeologists to access remote but well known destinations.
The Impact of Recommendation System Overuse on the Subjective Wellbeing of Internet Users
Authors: Hemans Morrant , Wiredu Ocansey Dickson Kofi
Published: March 2021

The stress in identifying useful information on the internet facilitated the use of recommendation systems by e-commerce and social network platforms to help users find their interested information quickly. However, this study seeks to investigate the impact of recommendation system overuse on the subjective wellbeing of internet users. The study reviewed previous studies in developing a research framework from the SOBC model that identifies social media overload as a (Situation) that triggers the intentions of internet users (Organism) to excessively use recommendation systems on the internet based on their level of self-concept clarity (Behavior) which (Consequently) affect their subjective wellbeing. SmartPLS 3.0 and SPSS v.22 software were deployed to analyze the research data and discover links between the constructs. The obtained results of the study confirm that, overuse of online recommendation systems negatively affect users’ subjective wellbeing.
Synthesis, Characterization and Biological Active 2 (Dimethylamino) Cyclohexane-1, 3-Dione
Authors: Jeyachandran Veerappan
Published: March 2021

In the present work, the precursors 2- ( ( dimethylamino ) methylene ) cyclohexane-1,3-dione 4 and 2- ( ( dimethylamino ) methylene ) -5, 5-dimethylcyclohexane-1,3-dione 5 were synthesized from the reaction of 1,3-cyclohexanedione 1 or 5,5-dimethyl-1,3-cyclohexandione 2 with DMF-DMA 3, respectively following literature procedure (Scheme 1).
Production, Purification and Characterization of Extracellular Lipase from a Mutated Strain of Penicillium Citrinum KU613360
Authors: Bhagya Lakshmi Lakkakula , Raghu Ram M
Published: March 2021

In the present study lipase production, purification and characterization were carried out with a novel fungal strain of Penicillium citrinum KU613360 isolated from vegetable oil contaminated soil samples collected from oil mills located in and around Guntur District, Andhra Pradesh, India. The strain improvement was carried out by subjecting the strain to both UV and Ethidium Bromide treatments. The wild strain of P. citrinum KU613360 showed maximum lipase activity of 1.053±0.32IUmL-1 on optimized medium and while the mutated strain treated with combination of UV (300 sec) and Et Br (200 µgcm3), recorded the enzyme activity of 4.260±0.011IUmL-1, using the optimised medium at 6.5 pH and 40°C temperature. Thus, a 404% enhancement in the activity was achieved by using induced mutation on wild strain of P. citrinum KU613360. The molecular weight of the purified lipase from the mutated strain was found to be 35 kDa, when analysed on SDS PAGE. From our results it was concluded that the mutated strain has considerable capability and potentiality to be used in various industrial applications.
Regulation of Collagen Synthesis in Tobacco/Pan-Masala Induced Oral Sub-Mucosal Fibrosis and Diagnostic Approach - Review Article
Authors: Awasthi Shraddha , Ahmad Ausaf , Srivastava Anand Narain
Published: March 2021

Introduction : oral submucosal fibrosis (OSMF) is related to juxta epithelial inflammatory response followed by a fibroelastic change of the lamina propria, with epithelial atrophy leading to stiffness of the oral mucosa, causing trismus and inability to eat.

Methods and Materials: The suitability standards for studies were: Research Articles that studied the metabolic activities in oral submucous fibrosis mainly caused by some carcinogenic substances or chemicals which may present in tobacco, alcohol, cigarettes, pan-masala etc Reference list of selected articles and reviews on the topic also were searched. studies were extracted, A total of 90-100 studies were extracted, using the keywords oral submucous fibrosis, oral potentially malignant lesion and diagnosis, collagen synthesis etc.,

Results: cancer risk among these patients, periodic biopsies of suspicious regions of the oral mucosa are essential for the early detection and management of high?risk oral premalignant lesions and prevention of cancer.

Conclusion: OSMF is hardly recognized and is poorly understood across the globe. significant improvement in management, nor reduction in its high malignant transformation rate. Better integration of medical and dental services, especially in developing countries, may reduce patients’ suffering and improve their life quality.
Formulasi Strategi Menggunakan Bisnis Model Canvas
Authors: Sugiyanto  , Muhammad Aditya Pratama  , Endang Wahyuningsih
Published: March 2021

The fashion industry plays an important role in the growth of the national creative industry which absorbs a lot of employment. Business actors selected as samples of this study were 4 distribution stores (Distros), located on Jl Padjadjaran, Bandung. Increasingly fierce competition is a major problem, marked by declining income and profitability. The purpose of this research is to formulate a distribution business strategy using SWOT analysis and BMC. Qualitative and quantitative descriptive research approaches were used in this study. Qualitative research to identify the factors of strengths, weaknesses, opportunities and threats. The results of the study found several factors from the elements of the SWOT analysis, as a basis for conducting quantitative analysis, which resulted in an aggressive strategy that had to be developed. Based on this strategy it is formulated in the form of a business model canvas. The distros business needs to be developed more aggressively in terms of Customer Segment, value proposition, channels, and customer relationships so that company revenue can increase. Companies also need to emphasize the development of the aspects of key business activities, key partners and the effectiveness of utilizing key resources so that the company can carry out cost efficiency. The finding of this study is that BMC can be used to describe briefly but completely as an effort to formulate a strategy for the results of SWOT analysis.
Pengaruh Kualitas Pelayanan Dan Fasilitas Terhadap Loyalitas Melalui Kepuasan Konsumen Pada Café Hangout Di Sampit
Authors: Yesi Triyuliarlita Amelia  , Koko Safitri
Published: March 2021

The purpose of this study was to determine the effect of service quality and facilities influence on loyalty in the cafe. Hangout Sampit consumer satisfaction as an intervention variable. By taking the sample using nonprobability sampling technique where sampling does not provide equal opportunities or opportunities for each element or member of the population to be selected as samples. The results of the Hypothesis Test in this study for the variable service quality (X1) to the Loyalty variable (Y) with the coefficient path is positive 0.91 with a P value <0.001 less than 0.05 and R-Square is 0.84 which means Quality service has a positive effect on loyalty with a large influence of 84%. Hypothesis test results for the Facility variable (X2) on Loyalty (Y) with a positive Path Coefficients value of 0.90 with a p value <0.001 less than 0.05 and R-Square of 0.82 means that facilities have a positive effect on loyalty. with a large influence of 82%. Hypothesis test results for the variable Product Quality (X1) on Customer Satisfaction (Z) with the value of Path Coefficients having a positive value of 0.94 with a p value <0.001 less than 0.05 and R-Square having a value of 0.89 which means that service quality has an effect positive on consumer satisfaction with a large effect of 89%. %. Hypothesis test results for the Facility variable (X2) on customer satisfaction (Z) with a positive path coefficients value of 0.94 with a p value <0.001 less than 0.05 and R-Square value of 0.89, it means that facilities have a positive effect on Consumer satisfaction with the influence of 89%. Hypothesis test results for the variable Customer Satisfaction (Z) on Loyalty (Y) with the value of Path Coefficients having a positive value of 0.95 with a p value <0.001 less than 0.05 and R-Square having a value of 0.91 which means that customer satisfaction has a positive effect to Loyalty with a big influence of 91%.