bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan E-Modul Berbasis STEAM untuk Meningkatkan Kemampuan Berpikir Tingkat Tinggi Pada Pembelajaran Tematik di Sekolah Dasar
Authors: Sari* Pratiwi Kartika , Sutihat Sutihat
Published: July 2022

The development of the world of education and technology has given birth to many challenges and real world problems to be faced. Students are required to utilize all their potential in a learning activity such as being able to build, synthesize, describe, evaluate, and create something from the knowledge they have into new knowledge in order to solve real-world problems. STEAM-based learning encourages students to explore their abilities. The development of a teaching material product in the form of a STEAM-based electronic module with the aim of improving higher-order thinking skills in high-grade thematic learning. This research is a development research, The model used in this research is the Dick and Carey development model. The validation results obtained from media experts are 82%, language is 89% and material is 84%, it can be said that the product developed is very feasible and can be tested. The next stage is a one to one trial, small group and field trials. The one to one trial got a score of 85% and the small group got a score of 90%. After that, entering the field trial, the results obtained were analyzed using the paired sample t-test. Before analyzing the data using the paired sample t-test, prerequisite tests were carried out, namely normality test and homogeneity test. The normality test obtained a result of 0,051, significance value 0.000. It can be stated that the STEAM-based electronic module can improve the higher-order thinking skills of high-class students
Profile of Senior High School Students’ Critical Thinking Skills and The Need of Implementation PBL Model Assisted by Augmented Reality Book
Authors: Saphira Hanandita Veda , Prahani* Binar Kurnia
Published: July 2022

Critical thinking skills of students in Indonesia are still very low, then one way to improve CTS is to collaborate learning with real-world problems that can be found in everyday life with the help of existing technology as a learning tool. The purpose of this research was to find out the profile of students' critical thinking skills and the implementation of problem based learning implementation with assisted augmented reality books in high schools, especially on learning physics with parabolic motion materials. The method research is included in preliminary research with a sample of 190 high school students in Surabaya, East Java. Data collection techniques by sharing critical thinking skills tests, student response surveys and interviews of students and teachers. Then the data is analyzed using qualitative descriptive to represent the results of the reserach. The findings of the study are 1) Students' critical thinking skills are still in the low category. 171 students with low categories, 19 medium categories and none at all high-category students; 2) The lowest indicator of critical thinking skills is interpretation; 3) Teachers still use conventional lecture methods and teaching materials during learning; 4) The implementation of problem-based learning models with integrated AR books is expected to improve students' critical thinking skills on physics materials. It can be concluded that to improve students' critical thinking skills, it is important to innovate learning, especially in physics learning, one of which is the implementation of Problem Based Learning assisted by Augmented Reality books.
Foreword
Authors: Hughes Kate
Published: July 2022

With thanks to reviewers of papers in this volume:

Ted Chapman, Alan Elliott, Dusty Gedge, Suzanne Hermiston, Rebecca Hilgenhof, Ben Jones, Phil Lusby, Clare Morter, Katherine O’Donnell, Michael Pirie, David Rae, Fred Rumsey, Paul Smith, John Wood, Ella May Wulff and anonymous reviewers.
Sosialisasi Penyediaan Air Minum dan Sanitasi Berbasis Masyarakat di Desa Teluk Kelansam
Authors: Herman Joni
Published: July 2022

Kesehatan lingkungan merupakan bagian dari dasar-dasar kesehatan masyarakat modern yang meliputi terhadap semua aspek manusia dalam hubungannya dengan lingkungan, dengan tujuan untuk meningkatkan dan memperttahankan nilai-nilai kesehatan manusia pada tingkat setinggi-tingginya dengan jalan memodifikasi tidak hanya faktor social dan lingkungan fisik semata-mata, tetapi juga terhadap semua sifat-sifat dan kelakukan-kelakuan lingkungan yang dapat membawa pengaruh terhadap ketenangan, kesehatan dan keselamatan organisme umat manusia. Suatu keseimbangan ekologi yang harus ada antara manusia dan lingkungan agar dapat menjamin keadaan sehat dari manusia. Lingkungan yang sehat mampu menopang keseimbangan ekologi yang dinamis antara manusia dan lingkungannya untuk mendukung tercapainya kualitas hidup manusia yang sehat dan bahagia. Kesehatan lingkungan meliputi, penyediaan Air Minum, pengelolaan air Buangan dan pengendalian pencemaran, pembuangan Sampah Padat, pengendalian vektor, pencegahan/pengendalian pencemaran tanah oleh ekskreta manusia, higiene makanan, termasuk higiene susu, pengendalian pencemaran udara, pengendalian radiasi, kesehatan kerja, pengendalian kebisingan, perumahan dan pemukiman, aspek kesling dan transportasi udara, perencanaan daerah dan perkotaan, pencegahan kecelakaan, rekreasi umum dan pariwisata, tindakan-tindakan sanitasi yang berhubungan dengan keadaan epidemi/ wabah, bencana alam dan perpindahan penduduk dan tindakan pencegahan yang diperlukan untuk menjamin lingkungan.
Edukasi Kesehatan Reproduksi Remaja dan Bahaya Sex Bebas di Madrasah Aliyah As’adiyah Lapai, Kec. Ngapa, Kolaka Utara
Authors: Alang Hasria , Hastuti Hastuti , Fitri Fitri , Hamdani Ibnu Mansyur
Published: July 2022

Kesehatan reproduksi adalah suatu cara untuk mencegah dan menyelesaikan masalah kesehatan reproduksi, seperti kesehatan fisik, mental dan sosial serta penyakit-penyakit yang ditularkan melalui hubungan seks.  Pendidikan kesehatan reproduksi sangat perlu dilakukan, terutama dikalangan remaja. Hal inii dikarenakan pada masa remaja, terjadi peralihan dari masa anak-anak menuju ke tahap dewasa. Begitu banyaknya perubahan yang dialami remaja, baik fisik maupun psikologisnya, membuat remaja acapkali mengalami berbagai permasalahan dalam kehidupan.  Tujuan edukasi kesehatan reproduksi diharapkan dapat mencegah dan melindungi remaja dari perilaku seksual beresiko yang dapat memengaruhi kesehatan reproduksinya sehingga dapat mempersiapkan remaja untuk menjalani kehidupan reproduksi yang sehat dan penuh tanggung jawab. Metode yang dilakukan dalam kegiatan ini adalah tatap muka dan ceramah interaktif kepada remaja MA As’adiyah Lapai. Sebelum pemaparan materi, dilakukan pretest untuk melihat sejauh mana pemahaman siswa/i dan diakhir diberikan post test. Hasil kegiatan dapat disimpulkan bahwa Kegiatan ini dapat meningkatkan pengetahuan dan pemahaman para siswa/i MA As’adiyah Lapai.
Budidaya Jamur pada Ibu-Ibu Rumah Tanga di Dusun Kruwet untuk Mewujudkan SDGs 2030
Authors: Rizky Lucitania , Pratiwi Tiffany Setyo , Chotimah Hidayat Chusnul , Iswardhana Muhammad Ridha , Wibawa Adi , Arisanto Puguh Toko
Published: July 2022

Budidaya jamur di Dusun Kruwet sebelumnya pernah diperkenalkan tetapi untuk produktivitas dan keberlanjutannya sempat terhenti karena permasalahan mengenai ketidakpahaman masyarakat dalam manajemen pengelolaan keuangan dan tidak adanya pelatihan dan pendampingan dalam budidaya jamur tersebut. Hal ini menjadikan kelompok ibu-ibu rumah tangga yang sebelumnya menjadi target pembinaan budidaya jamur pada awalnya hanya memanen jamur dari hasil hibah pembibitan saja tanpa mengetahui teknik untuk membuat bibit atau menyiapkan peralatan dan bahan untuk pembudidayaan jamur tersebut. Masyarakat setempat juga tidak paham mengenai agenda sustainable development goals (SDGs) 2030 yang merupakan tanggung jawab bersama dalam mewujudkannya. Dengan adanya permasalahan tersebut, Tim pengabdian masyarakat prodi Ilmu Hubungan Internasional, Universitas Teknologi Yogyakarta menawarkan pendampingan dengan mensosialisasikan agenda SDGs, pengenalan, pelatihan pembuatan media untuk penanaman jamur sampai pada tahap pemasaran hasil budidaya jamur sehingga kelompok ibu-ibu rumah tangga di Dusun Kruwet mampu menjadikan kegiatan ini sebagai salah satu upaya peningkatan ekonomi keluarga dan mewujudkan agenda SDGs 2030.
Atasi Bendungan Asi Pada Ibu Nifas Dengan Hipnobreastfeading Di Puskesmas Pembantu Penarukan, Tabanan
Authors: Purnamayanthi Pande Putu Indah , Ekajayanti Pande Putu Novi , Adhiestiani Ni Made Egar , Suparmi Wayan
Published: July 2022

Salah satu gangguan pada masa nifas yaitu bendungan ASI. Bendungan ASI disebabkan oleh pengeluaran air susu yang tidak lancar, karena bayi tidak cukup Air Susu Ibu (ASI), produksi ASI meningkat dimana ibu tidak sering menyusui bayinya, hubungan dengan bayi (bounding) kurang baik, dan dapat pula karena adanya pembatasan waktu menyusui. Tujuan penyuluhan ini adalah untuk meningkatkan keterampilan tentang teknik Hypnobreastfeeding dalam mengatasi bendungan ASI. Pelaksanaan kegiatan dan realisasi pemecahan masalah dilakukan dengan cara memberikan penyuluhan kepada ibu nifas yang mengalami bendungan ASI mengenai manfaat Hypnobreastfeeding, kemudian memberikan demonstrasi teknik Hypnobreastfeeding, untuk mengatasi bendungan ASI. Pelaksanaan kegiatan dan realisasi pemecahan masalah dilakukan dengan cara memberikan penyuluhan kepada ibu nifas yang mengalami bendungan ASI mengenai manfaat Hypnobreastfeeding, kemudian memberikan demonstrasi teknik Hypnobreastfeeding, untuk mengatasi bendungan ASI.
Pemanfaatan Sampah Organik Sebagai Bahan Baku Pembuatan Pupuk Organik Cair Bagi Warga Desa Kindang Bulukumba
Authors: Hartini Hartini , Apriyanti Eka , Alang Hasria
Published: July 2022

Sampah dari limbah rumah tangga apabila dibiarkan maka akan sangat mengganggu. Limbah rumah tangga seperti sisa sayuran dapat diolah menjadi hal yang bermanfaat yaitu menjadi pupuk organik cair (POC). Masyarakat Desa Kindang selama ini belum memahami tentang POC, sehingga limbah hanya dibuang di sekitar rumah. Hal ini tentu menyebabkan terjadi polusi udara. Selain itu, masyarakat Desa Kindang yang merupakan petani, khusus ibu-ibu dan remaja putri memiliki aktivitas tambahan untuk menyalurkan hobby berupa menanam tanaman hias di pekarangan. Pupuk kimia tentu menjadi pilhan agar tanaman hias mereka tumbuh subur. Hal ini tentu akan menambah anggaran atau pengeluaran. Berdasarkan hal tersebut, maka dilakukan pengabdian masyarakat di desa ini, dengan tujuan mengedukasi mitra tentang POC sehingga dapat mensubstitusi penggunaan pupuk kimia dengan cara memanfaatkan limbah menjadi barang yang berguna agar dapat mengurangi biaya pemeliharan tanaman mereka. Metode yang digunakan berupa ceramah tentang POC dan praktek pembuatan POC. Hasil kegiatan pengabdian ini dapat menambah pengetahuan mitra untuk memanfaatkan limbah menjadi barang yang berguna, yaitu sebagai POC.
Glokalisasi Pendidikan Ki Hajar Dewantara Pada Muslim Digital 4.0
Authors: Kusmawati Heny
Published: July 2022

Dalam tulisan ini penulis menggabungkan pendidikan Ki Hajar Dewantoro dalam prespektif globalisasi dan lokalisasi pada muslim digital 4.0. Sebagaimana diketahui pendidikan di Indonesia telah dimulai dari sebelum Indonesia merdeka, namun pendidikan di Indonesia hingga era revolusi industri 4.0 masih dalam kategori berkembang. Kemudian, penulis tertarik untuk mengikutsertakan pendidikan ki hajar dewantoro dalam balutan pendekatan globalisasi dan lokalisasi. Rumusan masalah tersebut adalah 1) Bagaimana Bagaimana kriteria glokalisasi pendidikan ki hajar dewantara pada muslim 4.0?. 2) Bagaimana langkah-langkah penyusunan glokalisasi pendidikan ki hajar dewantara pada muslim 4.0.  Dalam penulisan ini menggunakan metode penelitian kualitatif deskriptif dengan metode wawancara. Hasil penelitian: 1) a. Muslim mengadopsi sifat rasul sepert shidiq, amanah, fatonah, tablig, b. Mampu mengembangakan inti pendidikan ki hajar dewantara yakni ing ngarso sung tuladha, ing madya mangun karsa, dan tut wuri handayani kerangka dengan dimensi Islam internasional 2) a. Melakukan Pelatihan  Media Berbasis Digital, b. Memberikan Pembiasaan Perilaku Ing Ngarso Sung Tuladha Ing Madya Mangun Karsa, Tut Wuri Handayani.
Penyuluhan Mengenai Tentang Tanda Bahaya Anemia Pada Remaja Putri
Authors: Husna Husna , Saputri Ningsih
Published: July 2022

Anemia adalah masalah paling umum dijumpai terutama pada perempuan. Zat besi diperlukan untuk membentuk sel-sel darah merah, dikonversi menjadi hemoglobin, beredar ke seluruh jaringan tubuh, berfungsi sebagai pembawa oksigen. Solusi yang dilakukan dalam kegiatan pengabdian kepada masyarakat berupa memberikan penyuluhan mengenai tentang tanda bahaya anemia kepada remaja tepatnya remaja putri. Tujuan kegiatan pengabdian adalah untuk menambah pengetahuan rejama putri mengenai tentang tanda bahaya anemia dan perubahan perilaku remaja yang baik sehingga dapat meningkatkan status kesehatan. Manfaat kegiatan ini adalah agar remaja terutama remaja putri mengetahui tentang tanda bahaya anemia. Luaran kegiatan pengabdian yang diharapkan berupa adanya artikel yang terbit dalam jurnal pengabdian dan leaflet.
Minuman Herbal Modern "Jahe Float" Sebagai Inovasi Usaha Berbasis Kesehatan
Authors: Yanuarty Rezky
Published: July 2022

Jamu tradisional merupakan minuman berbahan rempah alami yang dipercaya memberikan manfaat kesehatan. Rempah berasal dari Jamu yang merupakan minuman dari campuran bermacam-macam tanaman herbal (kunyit, jahe, kencur, temulawak, sambiloto) yang dikemas dalam bentuk cair yang bisa langsung diminum. Salah satu inovasi yaitu membuat jamu herbal float atau "jahe float" inovasi ini dibuat untuk melestarikan penggunaan jamu dan dapat menarik minat masyarakat untuk melestarikan penggunaan jamu serta dapat menghilangkan rasa pahit. Tujuan dari pembuatan jahe float adalah tetap menggunakan minuman tradisional, namun dikemas lebih modern. Metode yang digunakan pada PKM dilakukan secara ceramah dengan membagikan brosur kepada masyarakat. Hasil survey dari PKM dengan jumlah responden sebanyak 30 orang, diperoleh indeks kepuasan sebanyak 3,53 dengan persentasi 87,78% dengan hasil sangat baik.
Pendidikan Kesehatan Tentang Pentingnya Personal Hygiene Pada Masa Nifas di Puskesmas Bowong Cindea Kab. Pangkep
Authors: Sari Lili Purnama
Published: July 2022

Masa nifas merupakan masa yang sangat rentan terhadap infeksi bagi ibu postpartum bila dalam perawatannya tidak tepat.Menjaga personal hygiene atau kebersihan tubuh pada masa nifas dalam suatu tindakan yang dilakukan untuk menjaga agar tubuh kita tetap bersih pada Saat nifas.Masa nifas berlangsung sekitar 6 minggu atau sekitar 40 hari. Selama masa pemulihan berlangsung, ibu akan mengalami banyak perubahan yaitu perubahan baik secara fisik maupun psikologis. Namun sebagian besar perubahan bersifat fisiologis dan jika tidak dilakukan pendamping melalui asuhan kebidanan maka tidak akan menutup kemungkinan akan terjadinya keadaan patologis. pegabdian ini bertujuan untuk memberikan pengetahuan dan keterampilan Tentang pentingnya Personal Hygiene di masa Nifas. Metode yang di gunakan penyuluhan dan praktek kepada masayarakat yang sasarannya adalah Ibu Nifas yang berjumlah 20 orang yang pelaksanaannya dilakukan selama 1 hari, Hasil pengabdian Semua Nifas memiliki pengetahuan dan keterampilan yang baik tentang pentingnya kebersihan diri dimasa Nifas ,serta adanya sikap positif untuk menerapkan personal hygiene secara mandiri  dirumah,Pemberian penyuluhan ini membuat ibu nifas menjadi antusias Untuk menjaga kebersihan diri dimasa Nifas.
Pendampingan Kader Dalam Pemberian Terapi Massage Punggung Pada Lansia Dengan Hipertensi Di Desa Adat Mawang Lodtunduh Gianyar
Authors: Rasdini IGA Ari , Rahayu VM Endang SP , Putrayasa IDP , Wedri Made
Published: July 2022

Hipertensi pada usia lanjut umumnya disertai dengan faktor resiko yang lebih berat. Relaksasi merupakan tindakan yang harus dilakukan pada setiap terapi antihipertensi. Masage punggung merupakan salah satu terapi yang efektif untuk menurunkan tekanan darah. Berdasarkan catatan medik di Puskesmas pembantu desa adat Mawang Lodtunduh Gianyar masih banyak ditemukan lansia dengan hipertensi tidak terkontrol. Melalui pengabdian mayarakat ini diharapkan para kader kesehatan mampu memberikan terapi masage punggung untuk mencegah komplikasi. Metode pendampingan dilakukan secara bertahap meliputi; pembentukan tim kader, merumuskan tujuan, melakukan pre tes terkait tehnik melakukan masage punggung, sosialisasi modul, memberikan vidio tentang tehnik masage punggung, pendampingan dalam memberikan terapi masage punggung kepada lansia hipertensi dan evaluasi dengan post tes. Hasil pengabdian didapatkan sebagian besar 60% pengetahuan kader tentang terapi masage punggung masih kurang sebelum diberikan pendampingan dan 90% memperoleh nilai baik setelah diberikan pendampingan. Melalui pendampingan pengetahuan dan ketrampilan kader meningkat. Direkomendasikan kepada para kader untuk memberikan terapi masage punggung secara berkala kepada lansia dengan hipertensi guna untuk mencegah komplikasi kardiovaskuler.
Literasi Barisan, Deret, Algoritma, Pemograman, dan Pengaplikasiaanya untuk Komputer Sains
Authors: Dalengkade Mario Nikolaus , Tjotjomare Yesti Norce Velanita , Loklomin Rukia , Woka Maria Elisabet , Ongis Triana , Buka Oktosea , Kutani Lian Fira , Yulia Devimega
Published: July 2022

Revolusi industri 4.0 menuntut perubahan dalam dunia pendidikan dimana tidak hanya menilai pada sisi akademik, tapi sampai pada tahap pengembangan soft skill dan technical skill dengan mengintegrasikan teknologi yang bermuara pada pembentukan karakter. Upaya yang dilakukan guna menunjang tuntutan tersebut, maka pelaksanaan kegiatan Pengabdian Kepada Masyarkat bertujuan mengkombinasikan teknologi dalam pembelajaran untuk materi barisan, deret, algoritma, dan pemograman di Sekolah Menengah Kejuruan Halmahera Utara. Guna mencapai tujuan, pendekatan yang dipakai yakni metode pemecahan masalah, dan pengukuran keberhasilan diukur menggunakan skala linkert. Hasil menunjukkan penggunaan metode pemecahan masalah meningkatkan pengetahuan akan materi yang dijabarkan pada rentang 8%-13%. Menelaah uraian singkat mengenai pendekatan metode pemecahan masalah dapat dikatakan berhasil, sehingga memungkinkan diaplikasikan dalam pembelajaran matematika.
The Development of Canada’s Pacific Gateway in the Age of Steam Globalization 1871-1939
Authors: Drent Jan
Published: July 2022

The completion of the Canadian Pacific Railway in 1886 made British Columbia’s coast Canada’s Pacific Gateway. Meanwhile, global trade boomed and growing marine traffic was supported by the systematic charting of the intricately indented British Columbia coastline, improved port infrastructure, and the creation of ship repair facilities. The opening of the Panama Canal in 1914 also resulted in a major boost to the Pacific Gateway. Vancouver became the dominant BC port and competed with eastern Canada for exports. This paper examines the main traffic flows through the Pacific Gateway and the development of its ports between 1871 and the start of the Second World War. L’achèvement du chemin de fer Canadien Pacifique en 1886 a fait de la côte de la Colombie-Britannique la porte d’entrée canadienne du Pacifique. En même temps, le commerce Mondial était en plein essor et l’augmentation de la circulation maritime était appuyée par la cartographie systématique de la côte découpée de la Colombie-Britannique, l’amélioration des infrastructures portuaires et la création d’installations de réparation de navires. L’ouverture du canal de Panama en 1914 a également donné un sérieux coup de pouce à la porte d’entrée du Pacifique. Vancouver est devenue le port le plus important de la Colombie-Britannique, faisant concurrence à l’est du Canada pour les exportations. Le présent article analyse les principaux courants de circulation dans la porte d’entrée du Pacifique et le développement de ses ports entre 1871 et le début de la Seconde Guerre mondiale.
Developing powerpoint-based interactive multimedia of mathematics learning multiples and factors materials for elementary school
Authors:   Elementary School Teacher Education Study Program, Sarjanawiyata Tamansiswa University, Yogyakarta, Indonesia, Nugroho Septian Adi , Trisniawati Trisniawati ,   Elementary School Teacher Education Study Program, Sarjanawiyata Tamansiswa University, Yogyakarta, Indonesia, Rhosyida Nelly ,   Elementary School Teacher Education Study Program, Sarjanawiyata Tamansiswa University, Yogyakarta, Indonesia
Published: July 2022

This research aims to describe PowerPoint-based interactive multimedia products in learning multiple material mathematics and class IV factors of the Karangtengah Baru, Imogiri State Elementary School, and describe the feasibility of the product. This research uses a development method or Research and Development (R&D), which includes six stages of development. The results of this development study show that the product developed meets valid and practical criteria. The validity can be categorized as "Very Good", with an average score of 4.6 and a percentage of 92%. The assessment results from media experts are categorized as "Good", with an average score of 3.9 and a percentage of 78.7%. The assessment results from media experts are categorized as "Good", with an average score of 3.9 and a percentage of 78.7%. Assessment from class teachers is categorized as "Very Good", with an average score of 4.7 and a percentage of 95.7%. Practicality seen from student response assessments can be categorized as "Very Good", with an average score of 4.7 and a percentage of 94% of 10 students as respondents. Based on the above exposure, it can be concluded that PowerPoint-based interactive multimedia products are developed and feasible for use in Class IV elementary mathematics learning multiple materials and factors.
Atypical Ulcer Arising on Stasis Dermatitis: Achromic Melanoma
Authors: Janowska Agata , Davini Giulia , Fidanzi Cristian , Dini Valentina , Loggini Barbara , Bagnoni Giovanni , Romanelli Marco , D’Erme Angelo
Published: July 2022

Introduction. Due to venous insufficiency, a vascular ulcer frequently occurs with the progression of stasis dermatitis. Achromic melanoma, a rare form of pigmentless melanoma frequently located on the sole of the foot, is often and easily confused with a typical wound. Diagnosis of ulcerated achromic melanoma is thus often delayed and associated with a poor prognosis. Case Report. The authors report a very rare case of malignant melanoma in a 70-year-old female with stasis dermatitis. The painless ulcer was present for 1 year before the first visit. Upon clinical examination, a 2-cm diameter hypergranulating ulcer with irregular and pigmented borders was present. Dermoscopy revealed the presence of red globules, a gray-to-blue veil, irregular vessels, and the remains of a pigmented ridge pattern. Histological analysis showed infiltration of atypical melanocytes in the dermis, 2 mitoses, and ulceration. Diagnosis of melanoma was confirmed by positive MART-1 immunochemistry. After removal of the melanoma, the area was covered with an autologous skin graft excised from the inner thigh. In accordance with the guidelines, sentinel lymph node biopsy was performed, and the result was negative for lymph node involvement. A comprehensive clinical dermoscopic evaluation led to the correct diagnosis. Conclusions. The current case highlights the importance of evaluating a chronic, atypical, nonhealing ulcer clinically and dermoscopically as well as through a biopsy procedure.
IMMUNOTOPIC ANOMALIES OF CONSTITUTION IN CHILDREN BORN FROM MOTHERS WITH TRANSPLANTED ORGANS AND TISSUES
Authors:   Republican Scientific and Practical Center “Mother and Child”, Minsk, Belarus, Simchenko A. V. , Devyaltovskaya M. G. ,   Republican Scientific and Practical Center “Mother and Child”, Minsk, Belarus
Published: July 2022

Constitutional anomalies are borderline variants of the body development. The purpose is to study the constitutional features in children born to mothers with transplants, as well as to assess the immunological status of these children during the first year of life. Material and methods. The immunological status of 18 children born to mothers with transplants was studied using monoclonal antibodies by indirect immunofluorescence during the first year of life. Results. The functional immaturity of the immune system in the form of insufficiency of the immunoregulatory link of immunity was established. We identified three types of immunotopic anomalies of the constitution in children born from mothers with transplanted organs: atopic, hyperergic and hypoimmune.
Enhanced Mechanical Stability and Scratch Resistance of Mesoporous Aluminosilicate Thin Films
Authors: Reid Barry , Mane Ishaa , Ahmed Faizah , Fornerod Maximiliano Jara , Füredi Máté , Alvarez-Fernandez Alberto , Guldin Stefan
Published: July 2022

Mesoporous coatings are widely used in industries such as optics, display technologies, photovoltaics, and bioengineering, due to their attractive properties such as high surface to volume ratio and excellent mass and electron transport characteristics. While structural parameters and material composition can be routinely tailored to the respective applications, improvements of their mechanical properties and robustness, essential for their long-term performance, remain a challenge. Herein, we provide a comprehensive study on the relationship between the degree of porosity, type of material processing and resulting mechanical properties for the use case of mesoporous aluminosilicate thin films that were co-assembled via a sacrificial block copolymer structure-directing agent. Several routes, including the introduction of chelating agents on the precursor solution, a two-step calcination process, and a variation over the aluminium content were explored with the objective of improving the scratch resistance and mechanical properties of the final mesoporous thin film. Pencil hardness tests were combined with atomic force microscopy analysis to investigate the macroscopic scratch resistance, i.e. plastic deformation. Ellipsometric porosimetry served to determine the elastic deformation of the nanoscopic architecture via measurement of the Young’s modulus. Our comparative investigation highlights the promising role of organic chelating agents to the sol-gel formulation to slow down the hydrolysis of the aluminium precursor, which facilitated improvements of the mechanical performance close to industrial standard.
Monitoring metabolic changes during storage of hazelnuts (Corylus avellana L.) by 1H NMR spectroscopy
Authors: Shakiba Navid , Lösel Henri , Wenk Soeren , Bachmann René , Creydt Marina , Seifert Stephan , Fischer Markus , Hackl Thomas
Published: July 2022

Storage is a critical step in post-harvest processing of hazelnuts since it can lead to mold, rancidity and off-flavor. To comprehensively investigate the effects of hazelnut storage, samples were stored under three short-term and two long-term conditions and the polar metabolome was analyzed by 1H NMR spectroscopy at different time points. Large differences in the polar metabolome were observed between the investigated storage conditions. Classification between samples before and after storage showed that samples stored under harsh conditions for a short-term and under standard conditions for a long-term were almost always classified correctly. Boruta, a feature selection algorithm, was used to identify which metabolites were significant for classification. Increases in hexanoic octanoic and nonanoic acid, all products of lipid oxidation, were found across all conditions and an increase in formic acid in most. Harsh short-term storage resulted in an increase in fumaric and lactic acid, glucose, fructose, and choline and a decrease in acetic acid.
Tris(2,4,6-trimethoxyphenyl)phosphine - a Lewis base able to compete with phosphazene bases in catalysing oxa-Michael reactions
Authors: Fischer Susanne, Maria , Kaschnitz Petra , Slugovc Christian
Published: July 2022

The performance of the strong Lewis base tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP) in catalysing oxa-Michael reactions is assessed and compared with other electron-rich tertiary arylphosphines and, as the benchmark, with the Brønsted base 1-tert-butyl-2,2,4,4,4-pentakis-(dimethylamino)-2λ5,4λ5-catenadi-(phosphazen) (P2-tBu). A matrix of five varyingly strong Michael acceptors and four varyingly acidic alcohols is used to evaluate the activity of the catalysts. The study attributes TTMPP a significant superiority over other arylphosphine based Lewis bases and a similar activity as P2-tBu under highly concentrated, quasi solvent free conditions. Furthermore, the performance of TTMPP and P2-tBu is compared in the oxa-Michael polymerisation reactions of 2-hydroxyethyl acrylate (HEA) and of 1,4-butanediol diacrylate (BDDA) with diols under solvent free conditions. In the case of HEA TTMPP is to be preferred over P2-tBu because the latter gave a not fully soluble polymeric product. TTMPP is the first Lewis base capable of catalysing the oxa-Michael polymerisation of diacrylates and diols, albeit P2-tBu catalysis results in higher molar masses in this polymerisation reaction. Furthermore, the performance of the catalysts under diluted conditions was assessed and the activity of TTMPP is distinctly more concentration dependent than the activity of P2-tBu. The use of the polar, protic solvent t-butanol mitigates the negative impact of dilution exerted by nonpolar, aprotic and polar, aprotic solvents such as toluene or dimethylformamide. Finally, data attesting TTMPP a limited, but for practical work under air still acceptable, stability to oxygen are disclosed.
Structural, Dynamical, and Entropic Differences Between SARS-CoV and SARS-CoV-2 s2m Elements Using Molecular Dynamics Simulations
Authors: Kensinger Adam H. , Makowski Joseph A. , Pellegrene Kendy A. , Imperatore Joshua A. , Cunningham Caylee L. , Frye Caleb J. , Lackey Patrick E. , Mihailescu Mihaela-Rita , Evanseck Jeffrey D.
Published: July 2022

The functional role of the highly conserved stem-loop II motif (s2m) in SARS-CoV and SARS-CoV-2 in the viral lifecycle remains enigmatic and an intense area of research. Structure and dynamics of the s2m are key to establishing a structure-function connection, yet a full set of atomistic resolution coordinates is not available for SARS-CoV-2 s2m. Our work constructs three-dimensional coordinates consistent with NMR solution phase data for SARS-CoV-2 s2m and provides a comparative analysis with its counterpart SARS-CoV s2m. We employed initial coordinates based on PDB ID: 1XJR for SARS-CoV s2m and two models for SARS-CoV-2 s2m: one based on 1XJR in which we introduced the mutations present in SARS-CoV-2 s2m and the second based on the available SARS-CoV-2 NMR NOE data supplemented with knowledge-based methods. For each of the three systems, 3500 ns molecular dynamics simulations were used to sample the structure and dynamics, and principal component analysis (PCA) reduced the ensembles to hierarchal conformational substates for detailed analysis. Dilute solution simulations of SARS-CoV s2m, demonstrate that the GNRA-like terminal pentaloop is rigidly defined by base stacking uniquely positioned for possible kissing dimer formation. However, the SARS-CoV-2 s2m simulation did not retain the reported crystallographic SARS-CoV motifs and the terminal loop expands to a highly dynamic “nonaloop.” Increased flexibility and structural disorganization are observed for the larger terminal loops, where an entropic penalty is computed to explain the experimentally observed reduction in kissing complex formation. Overall, both SARS-CoV and SARS-CoV-2 s2m elements have a similarly pronounced L-shape due to different motif interactions. Our study establishes the atomistic three-dimensional structure and uncovers dynamic differences that arise from s2m sequence changes, which sets the stage for the interrogation of different mechanistic pathways of suspected biological function.
Towards a mechanically rechargeable solid fuel flow battery based on earth-abundant materials
Authors: Fenton, Jr. Alexis M. , Ashraf Gandomi Yasser , Mallia Christopher T. , Neyhouse Bertrand J. , Kpeglo M. Aba , Exson William E. , Wan Charles Tai-Chieh , Brushett Fikile R.
Published: July 2022

Metal-air batteries are a promising energy storage solution, but materials limitations (e.g., metal passivation, low active material utilization) have stymied their adoption. We investigate a solid fuel flow battery (SFFB) architecture that combines the energy density of metal-air batteries with the modularity of redox flow batteries. Specifically, a metallic solid electrochemical fuel (SEF) is spatially separated from the anodic current collector; a dissolved redox mediator shuttles charge between the two, and an oxygen reduction cathode completes the circuit. This modification decouples power and energy system components while enabling mechanical recharging and mitigating the effects of non-uniform metal oxidation. We conduct an exploratory study showing that metallic SEFs can chemically reduce organic redox mediators repeatedly. We subsequently operate a proof-of-concept SFFB cell for ca. 25 days as an initial demonstration of technical feasibility. Overall, this work illustrates the potential of this storage concept and highlights scientific and engineering pathways to improvement.
Self-Acceptance as a Subjective Attribute
Authors:   Far Eastern Law Institute of the Ministry of Internal Affairs of Russia, Pilipenko T. S.
Published: July 2022

The article gives a brief theoretical review of studies of self-acceptance phenomenon by Russian and foreign psychologists. The author highlights the problem of the shift in understanding the concept of self-acceptance as an active process in favor passive self-acceptance, which often leads to intrapersonal regress, personality stagnation. The study focused on self-acceptance in the context of a subject-based approach. Based on the main provisions about a subject, in accordance with transforming activities of a subject, the author identified two types of self-acceptance – passive and active one. The author points out that it is active self-acceptance that is an actor’s attribute, and is related to such features of a subject as subject’s activity, integrity, autonomy, self-value. The empirical study has revealed the relation of self-acceptance to a general level of the development of personal agency and subject’s attributes.
Prioritizing noncommunicable diseases in the Americas region in the era of COVID-19
Authors: Luciani Silvana , Agurto Irene , Caixeta Roberta , Hennis Anselm
Published: July 2022

This article describes the situation of noncommunicable diseases (NCDs) in the Americas, implementation of NCD interventions according to key progress indicators, the impact of COVID-19 on NCD services, and ways to reprioritize NCDs following COVID-19. Information was retrieved from institutional data and through a supplementary scoping review of published articles related to NCDs and COVID-19 in the Americas published April 2020–November 2021. While NCDs account for 80.7% of all deaths in the Americas, implementation of a key set of NCD interventions has been limited, with only three countries reporting implementation of 12 or more of the 19 NCD indicators. By mid-May 2022, the Americas had reported about 29.9% of all COVID-19 cases in the world (154 million of 515 million) and 43.5% all COVID-19 deaths (2.7 million of 6.2 million). This pandemic has hampered progress on NCDs and significantly disrupted services for people who require ongoing care. Adaptive strategies, such as telehealth and mobile pharmacies, have been used to mitigate service disruptions. However, NCD prevention and management must be an integral part of recovering from the COVID-19 pandemic. This will require scaled up efforts to establish/re-establish and enforce policies on NCD risk factors, especially for tobacco control and obesity prevention, as well as greater investment in primary care and expansion of telemedicine and digital health solutions for continuous care for people with NCDs. Lastly, limited data are available on the impact of COVID-19 on NCDs, and hence NCD data and surveillance need to be strengthened.
Barreras de acceso a los servicios de salud para mujeres, niños y niñas en América Latina
Authors: Houghton Natalia , Báscolo Ernesto , Jara Lilia , Cuellar Catharina , Coitiño Andrés , del Riego Amalia , Ventura Edgar
Published: July 2022

Objetivo.

Determinar si existe una asociación entre las barreras de acceso informadas por mujeres de 15-49 años y la utilización de servicios esenciales de salud para mujeres, niños y niñas en América Latina.

Método.

Estudio transversal con base en modelos de regresión multivariada logística a partir de las Encuestas de Demografía y Salud de Bolivia, Haití, Honduras, Guatemala, Guyana, Nicaragua, Perú y República Dominicana.

Resultados.

Las barreras geográficas y financieras, la necesidad de obtener permiso para visitar al médico o no querer ir sola al establecimiento redujo significativamente la probabilidad de completar los controles prenatales y de tener un parto asistido. Las mujeres que notificaron dificultades para obtener permiso para visitar al médico redujeron su probabilidad de tener un examen de Papanicolau en los últimos 2 o 3 años, completar la vacunación de niños y niñas, y la probabilidad de buscar atención para sus hijos e hijas con cuadros de infección respiratoria aguda. No querer ir sola al centro de salud redujo la probabilidad de usar métodos anticonceptivos modernos.

Conclusiones.

La notificación de barreras de acceso por parte de las mujeres redujo de forma estadísticamente significativa la posibilidad de utilizar servicios esenciales de salud para ellas y para sus hijos e hijas. Las estrategias orientadas a eliminar barreras no solo deben enfocarse en mejorar la oferta de servicios, sino también abordar aspectos relacionados con las normas, los roles de género y el empoderamiento de las mujeres si se espera avanzar de manera sostenible hacia el acceso universal.
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer. (c2020)
Authors:   ,   Lebanese American University, El Mais Nour
Published: July 2022

Ovarian cancer being the first cause of death in gynecological diseases, paves the way towards increasing the search for a targeted therapy that could control the metastasis of a late-stage diagnosed ovarian cancer. HuArgI (Co)-PEG5000 is a potential drug to target cancers that depend on exogenous sources of arginine and cannot synthesize their own. In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. Our results show a decrease in the migratory rate of the cells and their rate in wound closure. The second thing we looked into was the adhesion of those cells and the formation of focal adhesions. The number and area of focal adhesions were quantified and the results show a decrease in the area and number of focal adhesions upon treating with HuArgI (Co)-PEG5000. Finally, we looked at the effect of HuArgI (Co)-PEG5000 on 3D motility of the ovarian cancer cell line, using a collagen based assay. It showed that SKOV3 cell line does not show significant invasiveness to collagen. In conclusion, we noticed an effect on ovarian cancer by treating the cells with HuArgI (Co)-PEG5000 which opens the way for further studies on the effect of arginine deprivation and autophagy induction on the migration of ovarian cancer.
Factorial Structure Determining The Intention To Vote Ecology
Authors: García Lirios Cruz
Published: July 2022

The political system in which it is possible to observe the similarities and differences between groups for and against presidential candidates based on processes of negotiation, mediation, conciliation and arbitration around the management and administration of Information Technologies and Communication is known as governance. This is a growing phenomenon as local or federal elections approach and digital networks are exacerbated as instruments for the promotion or dissuasion of a candidate. In this sense, the objective of the study was to optimize the Governance instrument of the Cyber Political Culture of Carreón (2016) in order to pay the reliability and validity of it; explore the relationship between preferences and expectations regarding voting intentions in a non-probabilistic sample of students using digital networks. From a structural model it was found that the consensus expectation factor determined the intentions to vote. The scope and limits of the exploratory factor analysis of main axes with a simple and oblique promax rotation regarding the confirmation of an orthogonal structure are discussed
The Role of Acehnese Women in Dealing With the Corvid-19 Pandemic Phenomenon
Authors: Alwi Alwi , Abdullah Taufik , Abubakar Muhammad Bin
Published: July 2022

The phenomenon of corvid 19 is a phenomenon that affects people's social changes to get used to a new social order called the "new normal". In an effort to reduce the number of people affected by corvid 19, the government has made various efforts through programs to comply with established health protocols. On the other hand, the success of suppressing the spread of corvid 19 is influenced by the role of women in prohibiting families from leaving the house and educating them to comply with health protocols set by the government. This study uses ground theory by paying attention to the behavior shown by the research subjects in achieving the corvid 19 phenomenon. The research approach carried out uses a qualitative approach that makes Acehnese women the object of research. The results showed that Acehnese women were able to provide stimulus in order to suppress the spread of corvid 19 during the pandemic. A different attitude is shown in the vaccination program, where Acehnese women experience a situation of distrust due to news information and government policies that are considered inconsistent.
Actualizing the affordances of machine translation tools for language learning
Authors: Alm Antonie
Published: July 2022

This paper investigates the use of machine translation tools (MTT) for reflective language learning. Drawing on Bowker’s (2020) concept of machine translation literacy, it suggests that machine translation tools can support learners in their language development if used critically. It argues that language learners should be supported to seek out affordances of MMT to develop machine translation literacies for specific language skills (reading, writing, listening and speaking) and vocabulary building. This paper presents the preliminary findings of a small-scale study involving ten advanced German language students who explored the features of MTT to meet their individual learning goals for reading. The process of affordance development was analyzed through the lens of Affordance-Actualization Theory.
Problems of field development control in the context of the “new economic policy”
Authors: Ipatov A.I. , Kremenetsky M.I.
Published: July 2022

Recent years in the domestic oil and gas production have been marked not only by trends towards the total digitalization of production processes, the introduction of high-tech equipment and the active entry of oil production companies into the development of fields with hard-to-recover hydrocarbon reserves, but also general trend associated with a radical change in the investment policy of operating companies. At the forefront of the majority of developers of domestic oil and gas, assets were the requirements for intensifying the return on financial investments in projects for the development and production of hydrocarbon resources. This factor was the reason for the authors to talk about the beginning of the era of the “new economic policy” in the oil and gas industry, which, unfortunately, cannot but affect the quality of operational processes and the degree of development of initially recoverable hydrocarbons. The authors examine several typical large oil fields, where a decrease in investment in diagnostics in the medium term preordained significant failures in the efficiency of the development of deposits and the inevitable losses in the residual volumes of recoverable hydrocarbon reserves.
Effects of bullying on the mental health of adolescents.
Authors: Uswah Bokhari  , Uswah Shoaib  , Farhat Ijaz  , Rana Khurram Aftab  , Musarrat Ijaz
Published: July 2022

Objective: To evaluate the effects of bullying on the mental effect of adolescents. Study Design: Cross Sectional study. Setting: Sacred Heart Convent School and Ibn e Sina School in Lahore. The data was compiled and analyzed at CMH Lahore Medical College. Period: November 2019-January 2020. Material & Methods: Three hundred and eighty one participants were selected from both schools and the severity of bullying was analyzed by using a Performa. The scores were calculated and compared with Victimization scale and WHO wellbeing index respectively. Results: The Victimization scale had a score range from 54 to 0. The mean was 8.04 with a Std. Deviation of 9.12. For the WHO well Being Index, 42.8% of total students scored less than 13, indicating negative impacts on mental health. 57.2% of students scored 13 or more. The correlation between Victimization Scale and WHO positive Wellbeing Index had a p-value of 0.844 which is insignificant, showing no correlation between the two variables.  Conclusion: In Pakistan, traditional bullying is common and is clearly related with lower general happiness and higher depression. There is a need to incorporate the promotion of anti-bullying programs and promote positive health as an integral part of the curriculums of Pakistani Schools.
Synthesis of Ferrocene Based Schiff Bases Possessing Different Metal Ion Sensing Aptitude and Partaking Antimicrobial Activity
Authors: Dhasarathan Saranya , Shunmugaperumal Selvaraj , Kamatchi Selvaraj P
Published: July 2022

Abstract. Schiff bases comprised of highly reactive ferrocene derivatives and normal aromatic moiety have been prepared successfully. Spectral variations noticed in the spectra of newly synthesized receptors for the addition of different metal ions discloses the multi metal ion sensing ability of the prepared sensors. Harmonization of Cu2+ ions with receptor originate as MLCT band in the visible region. Shrewdness made from the data obtained from cyclic voltammetry studies give an idea about the concentration of metal ions needed for effective sensing. In vitro antimicrobial studies and H- bond energy calculation for the interaction between the above sensory materials and proteins of selected microorganisms using molecular docking studies disclosures the antifungal activity of newly prepared materials.
 
Resumen. Bases de Schiff derivadas de grupos ferrocenilos altamente reactivos y grupos aromáticas fueron preparadas exitosamente. La habilidad de los sistemas como sensores para detectar diversos iones metálicos se vió en la variación de las características observadas en sus espectors. La interacción de iones Cu2+ con el receptor produce una banda MLCT en la región visible. Los estudios de voltametría cíclica indican la concentración de los iones metálicos necesaria para una detección eficiente. Estudios antimicrobianos in vitro y cálculos de la energía de puentes de hidrógeno para las interacciones entre los sensores (bases de Schiff) y las proteínas de microorganismos selectos, basados en estudios de acoplamiento molecular, confirman la actividad antifúngica de los nuevos compuestos reportados.