bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhancing Hotel Room Bookings through Instagram Marketing
Authors: Riza Zalzabilah Hadi Syahputri  , Muhammad Arfin Muhammad Salim  , Islahuddin
Published: July 2024

Tourism is a vital sector globally, encompassing travel, leisure, and associated industries that significantly bolster economies, especially in developed nations. Indonesia's tourism potential holds promise for economic growth through increased visitor numbers and new destination developments. The hotel industry, a cornerstone of global tourism, adapts to technological advancements and shifting consumer behaviors to maintain competitiveness. This study investigates the efficacy of Instagram as a digital marketing tool in enhancing hotel room bookings, focusing on Whiz Prime Hotel Sudirman Makassar. Methods included direct observation, engagement analysis, and stakeholder interviews. The findings underscore Instagram's pivotal role in showcasing hotel amenities, promotions, and exclusive offers to a global audience, thereby fostering direct engagement and influencing booking decisions. Effective strategies and challenges in leveraging Instagram were identified, highlighting the importance of innovative content, real-time responsiveness, and adaptation to digital trends. Despite challenges such as market saturation and evolving consumer preferences, proactive measures like enhancing content quality and collaborating with influencers can amplify Instagram's impact on room sales. Recommendations include continuous staff training, strategic partnerships, and analytics utilization to optimize marketing efforts and sustain growth in the competitive digital tourism landscape. This study contributes insights into leveraging Instagram for hotel marketing, emphasizing its role in driving profitability and enhancing brand visibility within the dynamic hospitality sector.
KONSEP ULUMUL QUR’AN SEBAGAI ILMU PENGETAHUAN AL-QUR’AN
Authors: AZIZAH HASNA NURUL , KHOTIMAH KHUSNUL
Published: July 2024

This article exists as a tool or reading to develop Islamic knowledge, especially the sciences contained in the Qur'an. Where the Al-Qur'an is the main source of basic legal sources used by Muslims in the various problems they face. To understand the Qur'an, various knowledge is needed, including "Ulumul Al-Qur'an". This knowledge includes discussions related to the Al-Qur'an in terms of the cause of its revelation, collection and sequence, knowledge of the verses makkiyah and madaniyyah, nasikh and mansukh and so on. The Ulumul Qur'an with its various branches and types was not born all at once, but through a process and development that can be divided into the transmission phase and the codification phase. For this article, the discussion will focus more on understanding the concept of Ulumul Qur'an as a science and discipline of Al-Quran knowledge, scope and branches of knowledge.
PENGARUH STRES KERJA DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN PADA PTPN V KEBUN SEI GALUH KABUPATEN KAMPAR
Authors: Dewanggi Natasha Elladitia
Published: July 2024

. Penelitian ini dilakukan pada PTPN V Kebun Sei Galuh Kabupaten Kampar. Tujuan penelitian ini adalah untuk mengetahui Pengaruh Stres Kerja (X1) dan Lingkungan Kerja (X2) terhadap Kinerja Karyawan (Y) pada PTPN V Kebun Sei Galuh Kabupaten Kampar, baik secara parsial maupun secara simultan. Adapun populasi dalam penelitian ini seluruh karyawan bagian SDM/Umum PTPN V Kebun Sei Galuh Kabupaten Kampar yang berjumlah 35 orang. Metode penentuan sampel dalam penelitian ini menggunakan total sampling. Data yang digunakan adalah data primer dan sekunder. Metode analisis data dalam penelitian ini adalah kuantitatif dengan menggunakan uji regresi linier berganda dan data dianalisis dengan menggunakan program SPSS. Hasil penelitian menunjukkan bahwa variabel Stres Kerja dan Lingkungan Kerja berpengaruh terhadap Kinerja Karyawan baik secara parsial maupun secara simultan. Hasil koefisien determinasi sebesar 0,679, hal ini menunjukkan bahwa variabel stres kerja dan lingkungan kerja secara keseluruhan memberikan pengaruh sebesar 67,9% terhadap kinerja karyawan sedangkan sisanya sebesar 32,1% dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
KUALITAS KEHIDUPAN KERJA TENAGA KESEHATAN PADA ORGANISASI PELAYANAN KESEHATAN
Authors: Anindita Maitri
Published: July 2024

Kualitas kehidupan kerja merupakan konsep komprehensif dan multidimensi yang memainkan peran penting dalam mempengaruhi kesejahteraan, kepuasan, dan produktivitas pegawai di tempat kerja. Pada sektor kesehatan, kualitas kehidupan kerja sangat penting karena tingginya tekanan dan tanggung jawab yang ditanggung oleh tenaga kesehatan, termasuk dokter, perawat, dan staf medis. Penelitian ini bertujuan untuk mengkaji berbagai faktor yang mempengaruhi kualitas kehidupan kerja pada tenaga kesehatan, dengan fokus khusus pada aspek-aspek seperti lingkungan kerja fisik, kondisi sosial dan budaya, keseimbangan kehidupan kerja, kompensasi, pengembangan profesional, dan mental. dukungan kesehatan. Temuan penelitian ini mengungkapkan bahwa beberapa faktor utama berdampak signifikan terhadap kualitas kehidupan kerja tenaga layanan kesehatan. Lingkungan kerja fisik yang mendukung terbukti penting dalam meningkatkan kepuasan kerja dan mengurangi tingkat stres di kalangan tenaga kesehatan. Kondisi sosial dan budaya juga memainkan peran penting dalam meningkatkan kualitas kehidupan kerja. Keseimbangan kehidupan kerja muncul sebagai faktor penting yang berkontribusi terhadap kesejahteraan fisik dan mental tenaga kesehatan yang lebih baik. Kompensasi yang adil dan kompetitif sangat penting dalam mempertahankan tingkat motivasi yang tinggi dan mengurangi tingkat turnover. Selain itu, peluang untuk pengembangan profesional dan jalur kemajuan karir yang jelas diidentifikasi sebagai kontributor terhadap kepuasan kerja dan kualitas kehidupan kerja secara keseluruhan. Dukungan kesehatan mental terbukti sangat penting dalam mengatasi tingginya tingkat kelelahan dan ketegangan emosional yang dialami oleh tenaga kesehatan. Penelitian ini juga menggarisbawahi pentingnya kebijakan dan peraturan pemerintah dalam menciptakan lingkungan kerja yang kondusif.
PENGARUH FINANCIAL TECHNOLOGY, FINANCIAL LITERACY, EKUITAS, DAN RELIGIUSITAS TERHADAP MINAT INVESTASI GENERASI Z DI PASAR MODAL SYARIAH PADA MAHASISWA DI KOTA PEKANBARU
Authors: Salsha Febrylia Melysha , Linda Roza
Published: July 2024

Penelitian ini dilakukan pada mahasiswa yang menempuh pendidikan universitas di Kota Pekanbaru. Tujuan dari penelitian ini untuk mengetahui pengaruh Financial Technology, Financial Literacy, Ekuitas, dan Religiusitas terhadap Minat Investasi Generasi Z di Pasar Modal Syariah mahasiswa universitas di Kota Pekanbaru. Penelitian menggunakan pendekatan kuantitatif dan analisis regresi berganda dengan populasi yaitu mahasiswa universitas di Kota Pekanbaru yang berjumlah 139.086 mahasiswa. Metode pengambilan sampel menggunakan non probability samping dengan pendekatan purposive sampling. Sampel penelitian ini berjumlah 269  mahasiswa. Hasil penelitian ini menunjukkan secara parsial financial technology, financial literacy, ekuitas dan religiusitas berpengaruh positif dan signifikan terhadap minat investasi generasi z di pasar modal syariah. Koefisien Determinasi (R²) dengan nilai 0,654 atau 65,4% variabel dependent penelitian ini dipengaruhi oleh financial technology, financial literacy, ekuitas dan religiusitas secara simultan sebesar 65,4%, sementara sisanya 34,6% dipengaruhi oleh variabel lain yang tidak digunakan dalam penelitian ini.
PELATIHAN SENI CUTTERISTIC SEBAGAI PELUANG USAHA INDUSTRI KREATIF PADA PONDOK PESANTREN AL- QUDS PEKANBARU
Authors: Linda Roza , Dwirianto Sabarno , Purba Khairunsyah , Rustam Afrinaldy
Published: July 2024

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pengetahuan tentang seni cutteristic sebagai peluang usaha industri kreatif. Metode kegiatan pengabdian dilakukan dengan metode caramah, tanya jawab dan praktek. Dalam mengevaluasi hasil yang dicapai dalam pengabdian ini menggunakan lembar observasi yang diberikan diawal dan diakhir kegiatan. Lembar observasi berisikan tentang motivasi dan minat, kerjasama dan kolaborasi, pengetahuan dan keterampilan, serta keberlanjutan pembuatan seni cutteristic secara mandiri. Kegiatan pengabdian dilaksanakan pada para santriwati di Pondok Pesantren Al- Quds Pekanbaru yang terdiri dari 50 orang santriwati dan 5 orang pengajar perempuan. Setelah berakhirnya kegiatan pengabdian masyarakat, peserta pelatihan  memiliki pengetahuan dan ketrampilan mengenai pembuatan seni cutteristic sebagai peluang usaha industri kreatif. Dari hasil angket yang disebar sebanyak 43 orang atau sebesar 98 % setuju bahwa seni cutterstic dapat dikembangkan menjadi peluang usaha.
«Les presento a María, correctora venezolana». Radiografía de la corrección en Venezuela
Authors: Tavares Lourenço Ricardo
Published: July 2024

El presente estudio describe la actividad profesional de los correctores venezolanos. Para ello, se difundió un cuestionario que fue respondido por 61 personas entre diciembre de 2021 y marzo de 2022. Luego, se aplicó la matriz FODA para establecer un diagnóstico sobre la actividad profesional. Se encontró que las fortalezas del corrector venezolano residen en el teletrabajo, en la capacidad de adaptación al entorno económico nacional y en la habilidad para monetizar y cobrar sus honorarios profesionales en divisas desde el exterior. Las debilidades se centran en la baja capacitación académica especializada en edición y corrección, en la poca asesoría en materia fiscal y presupuestaria, y en la tendencia a ejercer la corrección de manera informal. Las oportunidades se focalizan en la lengua española como plataforma para brindar servicios fuera del país y en la apertura de nuevos espacios que requieran la participación de correctores. Finalmente, las amenazas son la creciente disminución del mercado editorial venezolano y en los servicios deficientes de electricidad e internet que comprometen el cumplimiento de los compromisos laborales. Se concluye que urge crear una asociación para visibilizar, promocionar y mejorar las competencias de la corrección, así como diversificar la oferta de cursos de capacitación.
Selección de textos
Authors: Cardona Elena
Published: July 2024

N/A
Gladys Mendía. Luces altas, luces de peligro. Fox Island, WA, USA: LP5 Editora, 2022
Authors: Antequera Ortiz José
Published: July 2024

N/A
Sobre la perversidad: Pandora, Lilith y Eva en diálogo
Authors: Colina Emiro
Published: July 2024

El presente artículo gira en torno a tres personajes del imaginario fundacional, Pandora, Lilith y Eva. Aunque pertenecen a esferas míticas distintas, existen aspectos simbólicos circunscritos al terreno de la sospecha y la maldad. Transgresión, pecado, artificio, muerte son algunos eventos asociados a lo femenino, depositados en el ser que el pensamiento patriarcal propugnó en sus narrativas. Se recurre a los hallazgos de Bornay (1995), Escartín (2007), Cruzado (2009), entre otras voces, para ilustrar el estado del asunto. En la contemporaneidad pueden seguirse esta serie de coberturas mitológicas que configuraron, históricamente, a la mujer como signo cultural. No obstante, el espectro de discursos y posturas disidentes han fundado líneas de interpelación táctica que reivindican el rol de la figura femenina, de ahí la operatoria crítica y sus posibilidades interpretativas.
 
Palabras clave: Mito, símbolo, patriarcado, feminidad, figura femenina.
Aplicaciones de la lingüística al estudio de poemas y textos narrativos
Authors: Romero-Figueroa Andrés
Published: July 2024

Presentación del dossier de "Coloquios".
STUDYING THE FEATURES OF GLASS FORMATION OF ENAMEL FRITS FOR STEEL COVERING PANELS
Authors: Fanda Anna
Published: July 2024

Cladding of buildings and structures, combining decorative, protective and thermal insulation functions, is currently in great demand in the construction industry. One of the effective areas for using vitreous and glass-crystalline enamel coat-ings is the protection of steel cladding panels for construction purposes. Therefore, there is a need to create and widely implement competitive enamel-coated panels made in Russia with specified properties. The work identifies the areas of glass formation and constructs a composition diagram in the SiO2–B2O3–Na2O–RxOy system of glass areas, which are the basis for the production of ground and top enamels. The physicochemical patterns of glass formation in the Na2O–B2O3–Al2O3–SiO2–RxOy system for the production of enamel coatings have been established by varying the values of the connectivity indicators of the aluminum-boron-silicon-oxygen framework.
Literatura infantil y juvenil colombiana: problemas, tendencias, obras y autores (1990-2012)
Authors: Borja Maria , Alonso Arturo
Published: July 2024

En Colombia, hay autores y obras que dan cuenta de la literatura infantil y juvenil (LIJ), bien sea desde la idea de adaptación para los niños y los jóvenes de libros de la "gran literatura" para adultos, de literatura escrita para estas poblaciones o de literatura que niños y jóvenes se apropian para sí, a partir de la recomendación de un adulto o de las redes sociales y de los medios de comunicación masiva. A partir de la pregunta: ¿cuáles son los problemas, las tendencias, los autores y las obras más representativas de la literatura infantil y juvenil colombiana en los últimos veinte años? y con el interés por dar cuenta de la evolución de la literatura colombiana y del lugar que la LIJ se ha ido forjando en ella, este libro presenta el resultado de una investigación que indagó asuntos como los conceptos de literatura infantil y juvenil, las representaciones del niño y el joven como sujetos lectores, el lugar de la LIJ en la constitución del canon de la literatura colombiana, y la periodización en el marco de problemas y tendencias de la LIJ colombiana, entre 1990 y 2012.
أثر استراتيجية النطق المفرد في تحصيل مادة القراءة لدى تلميذات الصف الأول الابتدائي
Authors: الموسوي أنسام
Published: July 2024

يرمي هذا البحث الى تعرف أثر استراتيجية النطق المفرد في تحصيل مادة القراءة لدى تلميذات الصف الأول الابتدائي. تكونت عينة البحث من (63) تلميذة من تلميذات مدرسة المقاصد الابتدائية للبنات بعد استبعاد التلميذات الراسبين للعام الدراسي 2023 - 2024م. وتطلب ذلك بناء اداة البحث الحالي المتمثلة بالاختبار التحصيلي لمادة القراءة ، تم عرضه أمام مجموعة من الخبراء المتخصصين لتقييم مدى موثوقيته واستخلاص معاملات الصدق، بالإضافة إلى استحضار الخصائص السيكومترية للاختبار من خلال معاملات الثبات, واستعانت الباحثة بمجموعة من الوسائل الاحصائية تمثلت بـ الاختبار التائي لعينتين مستقلتين، مربع كا2، معادلة مستوى صعوبة الفقرة، ومعادلة مستوى تمييز الفقرة، وفاعلية البدائل الخاطئة، ومعادلة ألفا كرونباخ اما النتيجة التي توصلت اليها الباحثة هي:- وجود فرق ذي دلالة إحصائية عند مستوى دلالة (0,05) بين متوسط درجات تحصيل تلميذات مجموعتي البحث في مادة القراءة, ولمصلحة المجموعة التجريبية., وفي ضوء نتائج البحث يمكن للباحثة ان تستنتج ما يأتي: إستراتيجية النطق المفرد تظهر فعاليتها في العملية التعليمية بتوفير مناخ مناسب للمناقشة والبحث، وبالتالي تعزز فهم التلميذات وتسهم في تحقيق الحقائق, كما تجعل عملية التعلم مثيرة ومحفزة، مما يحسن نتائج التحصيل واوصت الباحثة عدة توصيات ومقترحات منها:-  تشجيع معلمات مادة القراءة على استعمال إستراتيجية النطق المفرد نظرًا للدلائل الإيجابية التي أظهرتها هذه الاستراتيجية
Prespektif Islam Terhadap Perilaku Menyimpang Lgbt Bagi Generasi Muda
Authors: Aprilia Tripuspita  , Annisa Aprilia
Published: July 2024

Seiring perkembangan zaman semakin bermacam juga bentuk penyimpangan yang ada, salah satunya yaitu LGBT. Banyak anak muda gen Z yang saat ini mulai menjadi kaum LGBT. Oleh sebab itu penelitian ini ditulis bertujuan untuk mengedukasi gen Z yang sudah menyimpang maupun yang belum, dengan menggunakan metode penelitian Kualitatif, kami menemukan faktor yang melatarbelakangi penyimpangan tersebut, juga pandangan Islam tentang LGBT. Faktor anak gen Z menganut LGBT adalah sebab faktor Lingkungan, perkembangan teknologi yang tidak diimbangi dengan Pendidikan agama, rasa kekecewaan, pernah menjadi korban, dan Rasa sepi. Faktor yang sangat berpengaruh memicu timbulnya LGBT yakni juga datang dari lingkungan dan tercatat 4 partisipan yang mengemukakan pendapat sama . Lingkungan bisa seputar lingkungan pertemanan, dunia kerja, dan sosial. Lingkungan pertemanan sangat mempengaruhi bagi generasi muda dalam hidupnya. Lingkup pertemanan yang terdiri didominasi oleh lawan jenis bisa menyebabkan seseorang mengikuti kepribadian lawan jenis tersebut. Sedangkan pandangan Agama Islam tentang LGBT yaitu haram dan merupakan bentuk dari zina.
Tahdzibul Akhlak Menurut Ibnu Maskawih Dan Urgensinya Dalam Dunia Pendidikan
Authors: Ussisa ‘alat Taqwa  , Wahyu Septrianto
Published: July 2024

Tahdzibul Akhlak adalah cabang ilmu dalam Islam yang membahas pengembangan akhlak individu dan masyarakat Muslim. Dalam konteks ini, Ibnu Maskawih memainkan peran penting dalam pengembangan konsep dan metodologi dalam tahdzibul akhlak. Karyanya yang terkenal, "Tahdzibul Akhlak," menjadi rujukan utama dalam memahami perilaku dan moralitas dalam Islam. Tujuan Tulisan ini untuk menyajikan latar belakang tentang Tahdzibul Akhlak menurut Ibnu Maskawih dan menjelaskan pentingnya Tahdzibul Akhlak diterapkan dalam dunia pendidikan. Dalam pendidikan, individu diajarkan untuk berhubungan dengan Allah dan mengembangkan kesadaran spiritual, memurnikan jiwa, dan mencari makna hidup yang lebih dalam. Dengan memasukkan Tahdzibul Akhlak dalam pendidikan, individu tidak hanya berkembang dalam hal pengetahuan akademik, tetapi juga dalam aspek moral, etika, sosial, dan spiritual. Hal ini penting untuk menciptakan karakter pribadi yang kuat, beretika, mampu berinteraksi dengan baik, dan memiliki pemahaman spiritual yang mendalam. Oleh karena itu, Tahdzibul Akhlak memiliki urgensi yang besar dalam pendidikan dalam membentuk individu yang baik dan berkontribusi dalam masyarakat serta memberi pemahaman yang lebih baik tentang pentingnya Tahdzibul Akhlak dalam kehidupan sehari-hari sebagai seorang Muslim, serta kontribusi Ibnu Maskawih dalam pengembangan bidang ini. Makalah ini juga mengajak pembaca untuk merenungkan nilai-nilai moral yang diajarkan oleh Ibnu Maskawih dan mengaplikasikannya dalam kehidupan mereka sendiri.
AN INSTITUTIONAL ECONOMICS ANALYSIS OF WEARING A MASK:INTERNALISING THE EXTERNALITY
Authors: a Bhat N Varada Shyama , Khandelwal Mahek
Published: July 2024

Human behaviour is the result of the circumstances and responses to various social factors considering the stakes involved in decision making. When the costs are high, individuals think and rationalize before bearing the cost; when the costs are low, individuals decide to bear the costs. This behavioural pattern can also be traced in the Indian masses reflex to the stimuli of various lockdown and unlock periods in the past six months. Initially, the fear of the unknown and uncertainty played a vital role in enforcing a lockdown and attempted imposition of social distancing to contain the spread of the novel coronavirus. As people became familiar with recovery rates, complacence grew, resulting in choking the already weak public administration and health infrastructure. To contain the surge of the virus, the Government responded by introducing a series of measures such as social distancing with lockdown, which resulted in shutting down the global economy3 resulting in an economic slump. The country has faced an acute shortage of money in terms of migrant labour crisis and a crumbling economy. The economy consists of various individual units working with self-interest in profit motives to reap economic benefits. Various disciplines observe and study parts of this pandemic, for instance, the medical fraternity focuses on developing a vaccine, the psychology aspect concerns itself with the mental health aspect, the financial aspect deals with the monetary policy and institutional economics provides the necessary tools to understand individual behaviour. Institutional economics does not restrict the study of individual behaviour to their purchasing power but rather extends to a study of their behaviour and decision making. This decision making includes economic decisions like savings and investments, expenditure patterns like buying Veblen goods and also decisions that affect the society at large like not wearing a mask and not complying with social distancing norms. Many learned individuals are of the opinion that until a vaccine is developed the only effective method to control the spread of the virus is to strictly wear a mask and adhere to the social distancing norms. wearing a mask and not complying with social distancing norms. Many learned individuals are of the opinion that until a vaccine is developed the only effective method to control the spread of the virus is to strictly wear a mask and adhere to the social distancing norms.
INTERNATIONAL COMMERCIAL ARBITRATION IN THE AFTERMATH OF THE PANDEMIC: A LAW AND ECONOMICS ACCOUNT
Authors: Arlota Carolina
Published: July 2024

This essay researches the main consequences of the pandemic caused by the COVID-19 virus in the field of international commercial arbitration through an economic analysis of law.1 This essay conceptualizes international commercial arbitration as an alternative mechanism for dispute resolution, focusing on how the pandemic may modify the incentives for parties in a different set of circumstances.
Editorial
Authors: Carneiro Reginaldo Fernando , Soares Flávia dos Santos
Published: July 2024

Editorial
Justiça social e coletividade na formação de professores que ensinam matemática
Authors: Cedro Wellington , Lopes Anemari Roesler Luersen Vieira , Moura Manoel Oriosvaldo de
Published: July 2024

Este artigo tem como objetivo problematizar a formação de professores que ensinam matemática com base na discussão entre os conceitos de justiça social e coletividade. Trata-se de um ensaio teórico no qual apresentamos como um projeto desenvolvido no âmbito das universidades e das escolas de educação básica pode ser constituir como um espaço profícuo para a formação do professor que ensina matemática. Sustentados principalmente nas ideias advindas da teoria histórico-cultural, apresentam-se os principais elementos teóricos que fundamentam a formação do professor no âmbito do projeto Clube de Matemática. Destaca-se neste artigo a possibilidade do desenvolvimento da coletividade como uma das formas da superação das condições opressoras e alienantes que dominam o atual contexto de formação de professores em nosso país.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN DIET PASIEN DIABETES MELITUS TIPE II DIWILAYAH KERJA PUSKESMAS KURAITAJI KOTA PARIAMAN
Authors: ASMIATI ASMIATI , NOER SALMAN , SANTI NOVITA
Published: July 2024

Diabetes triggers 6.7 million deaths or 1 case every 5 seconds in sufferers. Indonesia is in fifth position for diabetes sufferers, namely 19.47 million. The study aims to determine the relationship between family support and dietary compliance of type 2 diabetes mellitus patients in the Kuraitaji Health Center Work Area, Pariaman City. This type of research is descriptive analytical with a cross-sectional approach design. The population in this study were 366 Type II DM sufferers. Sampling used a random sampling technique with a total of 65 people. Data collection was carried out by documentation study and computerized data processing, using univariate and bivariate analysis. The results of the univariate analysis showed that 47 respondents (60.3%) had insufficient family support, 8 respondents (10.3%) had sufficient family support, and 23 respondents (29.5%) had good family support. Type 2 DM sufferers who had non-compliance were 47 respondents (60.3%), and compliance was 31 respondents (39.7%). The results of the bivariate analysis showed a significant relationship between family support and dietary compliance in type II diabetes mellitus patients (p-value = 0.000 ≤ 0.05). In conclusion, family support is related to the level of compliance of patients with type 2 diabetes mellitus at the Kurai Taji Health Center, Pariaman City in 2022.
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KESIAPAN MENGAHADAPI MENARCHE PADA SISWI KELAS V DAN VI SDN 11 NAN SABARIS KABUPATEN PADANG PARIAMAN
Authors: MAIFITA YESI , SAFITRI WELLIANI
Published: July 2024

Knowledge of adolescent girls related to early signs of puberty in the form of menarche (first menstruation) is still low in Padang Pariaman Regency. Meanwhile, adolescent girls should have sufficient knowledge and information to face menarche. The purpose of this study was to determine the relationship between the level of knowledge and readiness to face menarche in grade V and VI students of SDN 11 Nan Sabaris, Padang Pariaman Regency. The method used in this study was descriptive analytical using a cross-sectional approach. The population in this study were 30 grade V and VI students of SDN 11 Nan Sabaris. Sampling was done using the total sampling technique so that the sample size was 30 people. The instrument ini this research was questionnaire. Data processing was computerized with Chi-Square analysis at α = 5%. The results showed that 66.7% of respondents had high knowledge and 70.0% of respondents were ready to face menarche. Bivariate chi square analysis showed that p-value = 0.00 which means there is a significant relationship between the level of knowledge and readiness to face menarche in grade V and VI students of SDN 11 Nan Sabaris (p-value = 0.00 <α = 0.05). The conclusion of this study is that the level of adolescent knowledge in facing menarche in grade V and VI students of Nan Sabaris is related to their readiness.
L’urgence climatique et les droits des personnes handicapées : état des lieux et perspectives1
Authors: Jodoin Sébastien , Paquet Rose , Lofts Katherine
Published: July 2024

Cet article interroge le rôle que peut jouer le droit du handicap dans la lutte au changement climatique. En nous appuyant sur la Convention des Nations Unies relative aux droits des personnes handicapées, nous précisons les obligations des États envers les personnes handicapées dans le domaine des changements climatiques. Nous expliquons également que la vulnérabilité accrue des personnes handicapées dans la crise climatique résulte de l’interaction entre les incapacités des individus et les barrières institutionnelles, économiques, comportementales et environnementales auxquels ils sont confrontés dans la société. Nous présentons ensuite les résultats d’une analyse systématique de la protection des droits des personnes handicapées dans le contexte des politiques climatiques adoptées autour du monde. Enfin, nous terminons par une présentation des contentieux climatiques liés aux droits des personnes handicapées. Nous suggérons que des solutions climatiques inclusives du handicap sont non seulement essentielles pour protéger les droits et la dignité des personnes handicapées, mais qu’elles pourraient permettre à une plus grande partie de la population de contribuer à l’émergence de sociétés sobres en carbone et d’améliorer leur résilience climatique.
Validity and Reliability of the Turkish Version of the Patient-Reported Impact of Spasticity Measure in Multiple Sclerosis
Authors: Yalçın Gizem Yağmur , Dünya Cansu Polat , Yeni Kübra , Kürtüncü Murat , Tulek Zeliha , Gündüz Tuncay , Eraksoy Mefküre
Published: July 2024

BACKGROUND:

We aimed to evaluate the validity and reliability of the Turkish version of the Patient-Reported Impact of Spasticity Measure (PRISM-TR).

METHODS:

Expert opinions and the forward-back translation method were used for linguistic validation. Cronbach α and test-retest analysis were performed for reliability analysis. Correlations between the PRISM-TR and the Modified Ashworth Scale (MAS), the Numerical Rating Scale (NRS), and the Expanded Disability Status Scale (EDSS) were assessed.

RESULTS:

A total of 206 individuals with multiple sclerosis (MS; 139 women; mean age, 47.7 ± 11.3 years; mean EDSS score, 5.2 ± 1.5) who had not had a relapse in the previous 3 months were included in the study. Test-retest correlation coefficients were high for all subdimensions of the scale (0.95-0.99). All Cronbach α values for the PRISM-TR subdimensions, except for Positive Impact, were likewise quite high (0.85-0.94). PRISM-TR subscale scores were correlated with MAS, NRS, and EDSS scores (P < .001).

CONCLUSIONS:

PRISM-TR is a valid and reliable scale for use with Turkish individuals with MS. It is simple to use in the clinic and can be helpful in detecting patients’ spasticity early in the disease course.
A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria
Authors: Faniyan Tumininu S , Zhang Xinyi , Morgan Donald A , Robles Jorge , Bathina Siresha , Brookes Paul S , Rahmouni Kamal , Perry Rachel J , Chhabra Kavaljit H
Published: July 2024

The kidneys facilitate energy conservation through reabsorption of nutrients including glucose. Almost all the filtered blood glucose is reabsorbed by the kidneys. Loss of glucose in urine (glycosuria) is offset by an increase in endogenous glucose production to maintain normal energy supply in the body. How the body senses this glucose loss and consequently enhances glucose production is unclear. Using renal
Glut2
knockout mice, we demonstrate that elevated glycosuria activates the hypothalamic-pituitary-adrenal axis, which in turn drives endogenous glucose production. This phenotype was attenuated by selective afferent renal denervation, indicating the involvement of the afferent nerves in promoting the compensatory increase in glucose production. In addition, through plasma proteomics analyses we observed that acute phase proteins - which are usually involved in body’s defense mechanisms against a threat – were the top candidates which were either upregulated or downregulated in renal
Glut2
KO mice. Overall, afferent renal nerves contribute to promoting endogenous glucose production in response to elevated glycosuria and loss of glucose in urine is sensed as a biological threat in mice. These findings may be useful in improving efficiency of drugs like SGLT2 inhibitors that are intended to treat hyperglycemia by enhancing glycosuria but are met with a compensatory increase in endogenous glucose production.
Xanthomonas citri subsp. citri type III effector PthA4 directs the dynamical expression of a putative citrus carbohydrate-binding protein gene for canker formation
Authors: Chen Xinyu , Zou Huasong , Zhuo Tao , Rou Wei , Wu Wei , Fan Xiaojing
Published: July 2024

Xanthomonas citri
subsp.
citri
(
Xcc
), the causal agent of citrus canker, elicits canker symptoms in citrus plants because of the transcriptional activator-like (TAL) effector PthA4, which activates the expression of the citrus susceptibility gene
CsLOB1
. This study reports the regulation of the putative carbohydrate-binding protein gene
Cs9g12620
by PthA4-mediated induction of CsLOB1 during
Xcc
infection. We found that the transcription of
Cs9g12620
was induced by infection with
Xcc
in a PthA4-dependent manner. Even though it specifically bound to a putative TAL effector-binding element in the
Cs9g12620
promoter, PthA4 exerted a suppressive effect on the promoter activity. In contrast, CsLOB1 bound to the
Cs9g12620
promoter to activate its expression. The silencing of
CsLOB1
significantly reduced the level of expression of
Cs9g12620
, which demonstrated that
Cs9g12620
was directly regulated by CsLOB1. Intriguingly, PhtA4 interacted with CsLOB1 and exerted feedback control that suppressed the induction of expression of
Cs9g12620
by CsLOB1. Transient overexpression and gene silencing revealed that
Cs9g12620
was required for the optimal development of canker symptoms. These results support the hypothesis that the expression of
Cs9g12620
is dynamically directed by PthA4 for canker formation through the PthA4-mediated induction of CsLOB1.
Diverse prey capture strategies in teleost larvae
Authors: Mearns Duncan S , Hunt Sydney A , Schneider Martin W , Parker Ash V , Stemmer Manuel , Baier Herwig
Published: July 2024

Animal behavior is adapted to the sensory environment in which it evolved, while also being constrained by physical limits, evolutionary history, and developmental trajectories. The hunting behavior of larval zebrafish (
Danio rerio
), a cyprinid native to streams in Eastern India, has been well characterized. However, it is unknown if the complement and sequence of movements employed during prey capture by zebrafish is universal across freshwater teleosts. Here, we explore the syntax of prey capture behavior in larval fish belonging to the clade
Percomorpha
, whose last common ancestor with cyprinids lived ∼240 million years ago. We compared the behavior of four cichlid species from Lake Tanganyika endemic to deep benthic parts of the lake (
Lepidiolamprologus attenuatus
,
Lamprologus ocellatus
, and
Neolamprologus multifasciatus
) or inhabiting rivers (
Astatotilapia burtoni
) with that of medaka (
Oryzias latipes
), a fish found in rice paddies in East Asia. Using high speed videography and neural networks, we tracked eye movements and extracted swim kinematics during hunting from larvae of these five species. Notably, we found that the repertoire of hunting movements of cichlids is broader than that of zebrafish, but shares basic features, such as eye convergence, positioning of prey centrally in the binocular visual field, and discrete prey capture bouts, including two kinds of capture strikes. In contrast, medaka swim continuously, track the prey monocularly without eye convergence, and position prey laterally before capturing them with a side swing. This configuration of kinematic motifs suggests that medaka may judge distance to prey predominantly by motion parallax, while cichlids and zebrafish may mainly use binocular visual cues. Together, our study documents the diversification of locomotor and oculomotor adaptations among hunting teleost larvae.
Decoding phase separation of prion-like domains through data-driven scaling laws
Authors: Maristany M Julia , Gonzalez Anne Aguirre , Espinosa Jorge R , Huertas Jan , Collepardo-Guevara Rosana , Joseph Jerelle A
Published: July 2024

Proteins containing prion-like low complexity domains (PLDs) are common drivers of the formation of biomolecular condensates and are prone to misregulation due to amino acid mutations. Here, we exploit the accuracy of our residue-resolution coarse-grained model, Mpipi, to quantify the impact of amino acid mutations on the stability of 140 PLD mutants from six proteins (hnRNPA1, TDP43, FUS, EWSR1, RBM14, and TIA1). Our simulations reveal the existence of scaling laws that quantify the range of change in the critical solution temperature of PLDs as a function of the number and type of amino acid sequence mutations. These rules are consistent with the physicochemical properties of the mutations and extend across the entire family tested, suggesting that scaling laws can be used as tools to predict changes in the stability of PLD condensates. Our work offers a quantitative lens into how the emergent behavior of PLD solutions vary in response to physicochemical changes of single PLD molecules.
The Bowed Lyre of Estonia’s Swedes: Origin, Diffusion, Decline, Revival
Authors: Haas Ain ,   Indiana University at Indianapolis, USA
Published: July 2024

Once played across Northern Europe in the Middle Ages, as early as the Viking Era, the bowed lyre has survived in an unbroken tradition in the Baltic region. The traditional playing method uses a loosely strung bow to stroke drone and melody strings simultaneously, while pressing the latter with knuckles or fingernails through a handhole. Iconographic, archeological, and ethnographic evidence points to the likely derivation of the bowed lyre from the bowed lute of Moorish Iberia or the Byzantine Empire. After a long decline in popularity, revivals occurred in Sweden (1970s), Finland (1980s), and Estonia (1990s). Focusing on the last case, the analysis shows how international contacts led to the bowed lyre’s emergence and diffusion, as well as to its decline and revival. Traditional designs, tuning schemes, playing styles, and repertoire are still preserved today, though the social function, lore transmission, and performance settings of the bowed lyre have changed.
Identifying highly connected sites for risk-based surveillance and control of cucurbit downy mildew in the eastern United States
Authors: Ojwang’ Awino M. E. , Lloyd Alun L. , Bhattacharyya Sharmodeep , Chatterjee Shirshendu , Gent David H. , Ojiambo Peter S.
Published: July 2024

Objective

Surveillance is critical for the rapid implementation of control measures for diseases caused by aerially dispersed plant pathogens, but such programs can be resource-intensive, especially for epidemics caused by long-distance dispersed pathogens. The current cucurbit downy mildew platform for monitoring, predicting and communicating the risk of disease spread in the United States is expensive to maintain. In this study, we focused on identifying sites critical for surveillance and treatment in an attempt to reduce disease monitoring costs and determine where control may be applied to mitigate the risk of disease spread.

Methods

Static networks were constructed based on the distance between fields, while dynamic networks were constructed based on the distance between fields and wind speed and direction, using disease data collected from 2008 to 2016. Three strategies were used to identify highly connected field sites. First, the probability of pathogen transmission between nodes and the probability of node infection were modeled over a discrete weekly time step within an epidemic year. Second, nodes identified as important were selectively removed from networks and the probability of node infection was recalculated in each epidemic year. Third, the recurring patterns of node infection were analyzed across epidemic years.

Results

Static networks exhibited scale-free properties where the node degree followed a power-law distribution. Betweenness centrality was the most useful metric for identifying important nodes within the networks that were associated with disease transmission and prediction. Based on betweenness centrality, field sites in Maryland, North Carolina, Ohio, South Carolina and Virginia were the most central in the disease network across epidemic years. Removing field sites identified as important limited the predicted risk of disease spread based on the dynamic network model.

Conclusions

Combining the dynamic network model and centrality metrics facilitated the identification of highly connected fields in the southeastern United States and the mid-Atlantic region. These highly connected sites may be used to inform surveillance and strategies for controlling cucurbit downy mildew in the eastern United States.
Methodology for the assessment of poor-data water resources
Authors: Navarro-Farfán María del Mar , García-Romero Liliana , Martínez-Cinco Marco A. , Domínguez-Sánchez Constantino , Sánchez-Quispe Sonia Tatiana
Published: July 2024

Surface hydrologic modeling becomes a problem when insufficient spatial and temporal information is available. It is common to have useful modeling periods of less than 15 years. The purpose of this work is to develop a methodology that allows the selection of meteorological and hydrometric stations that are suitable for modeling when information is scarce in the area. Based on the scarcity of data, a series of statistical tests are proposed to eliminate stations according to a decision-making process. Although the number of stations decreases drastically, the information used is reliable and of adequate quality, ensuring less uncertainty in the surface simulation models. Individual basin modeling can be carried out considering the poor data. The transfer of parameters can be applied through the nesting of basins to have information distributed over an extensive area. Therefore, temporally and spatially extended modeling can be achieved with information that preserves statistical parameters over time. If data management and validation is performed, the modeled watersheds are well represented; if this is not done, only 26% to 50% of the runoff is represented.
The use of vocal coordination in male African elephant group departures: evidence of active leadership and consensus
Authors: O’Connell-Rodwell Caitlin E. , Berezin Jodie L. , Pignatelli Alessio , Rodwell Timothy C.
Published: July 2024

Group-living animals engage in coordinated vocalizations to depart from a location as a group, and often, to come to a consensus about the direction of movement. Here, we document for the first time, the use of coordinated vocalizations, the “let’s go” rumble, in wild male African elephant group departures from a waterhole. We recorded vocalizations and collected behavioral data as known individuals engaged in these vocal bouts during June-July field seasons in 2005, 2007, 2011, and 2017 at Mushara waterhole within Etosha National Park, Namibia. During departure events, we documented which individuals were involved in the calls, the signature structure of each individual’s calls, as well as the ordering of callers, the social status of the callers, and those who initiated departure. The “let’s go” rumble was previously described in tight-knit family groups to keep the family together during coordinated departures. Male elephants are described as living in loose social groups, making this finding particularly striking. We found that this vocal coordination occurs in groups of closely associated, highly bonded individuals and rarely occurs between looser associates. The three individuals most likely to initiate the “let’s go” rumble bouts were all highly socially integrated, and one of these individuals was also the most dominant overall. This finding suggests that more socially integrated individuals might be more likely to initiate, or lead, a close group of associates in the context of leaving the waterhole, just as a high-ranking female would do in a family group. The fact that many individuals were involved in the vocal bouts, and that departure periods could be shorter, longer, or the same amount of time as pre-departure periods, all suggest that there is consensus with regard to the act of leaving, even though the event was triggered by a lead individual.
Inference from RDS data over Directed Networks
Authors:   , Sepúlveda Peñaloza Alejandro Adrián
Published: July 2024

El muestreo dirigido por los encuestados (Respondent-Driven Sampling, RDS) es una técnica utilizada para recolectar datos de poblaciones humanas socialmente conectadas que no tienen un marco de muestreo definido. Un paso fundamental para realizar inferencias basadas en el diseño de datos RDS es estimar las probabilidades de muestreo. Tradicionalmente, se ha asumido que una cadena de Markov de primer orden sobre una red completamente conectada y no dirigida representa adecuadamente el RDS. Sin embargo, este modelo simplificado no tiene en cuenta que la red puede ser dirigida y homofílica. Este trabajo propone métodos para abordar estos problemas y estimar la prevalencia de un estado de infección en redes de este tipo.Las principales contribuciones metodológicas de esta tesis son tres: primero, la introducción de un modelo de configuración de red parcialmente dirigida y homofílica; segundo, el desarrollo de dos representaciones matemáticas del proceso de muestreo RDS en el modelo propuesto; y tercero, la propuesta de un modelo bayesiano que considera una red dirigida y el número de conexiones entre nodos infectados y no infectados para estimar la prevalencia del estado de infección.Se realizaron estudios de simulación para demostrar que las probabilidades de muestreo resultantes con nuestras propuestas son similares a las del RDS tradicional, mejorando la estimación de prevalencia bajo diversos escenarios realistas, asumiendo que dichas probabilidades son conocidas. La estimación de la prevalencia del estado de infección se realiza bajo fuertes suposiciones sobre la red, como la ausencia de homofilia o la dirección de los bordes.Para la aplicación del modelo, se utilizó la teoría de copulas, el modelamiento de distribuciones marginales y un modelo de superpoblación para estimar información a partir de datos no observados de la red. Las simulaciones realizadas mostraron una mejora en la estimación de la prevalencia del estado de infección en términos de sesgo y variabilidad utilizando datos de RDS.
Potential Role of Immature Platelet Fraction in Dengue Fever: A Narrative Review
Authors: Gupta Reshu , Mehta Adrija , Singh Shatakshi , Shah Saksham , Luthra Divyanshi
Published: July 2024

Dengue fever has emerged as a major international public health concern with a dramatic global increase in its frequency over the past few decades. It may present as a mild illness to a life-threatening condition with the major pathophysiological hallmark being plasma leakage as a result of increased vascular permeability and haematological abnormalities. The unpredictable nature and progression of the disease has led to research of novel haematological markers like Immature Platelet Fraction (IPF) which may help enhance the precision and efficacy of dengue management strategies by guiding the need for blood transfusion and blood lab monitoring, decreasing financial cost and hospital stay. This review provides detailed information about the immunopathogenesis of dengue, which is responsible for the fatal complexities and also gives the definition and uses of IPF by the healthcare workers. It aims to delve into the evolving role of IPF in the management of dengue, exploring its potential applications in assessing disease severity, predicting haemorrhagic tendencies and guiding therapeutic interventions. The review informs the readers about the implications and significance of the use of IPF in the treatment of dengue and how this technique can potentially reduce disease severity by timely diagnosis and treatment.
Enhancing Animal Nutrition and Sustainability: The Vital Role of Genetically Modified Crops in Animal Feeding
Authors: Siddiqui Rukkiya , Mondal B.C. , Raza Meesam , Kumar Sawan , Goswami Rashmi , Rafiqui Muteeb Ullah , Ahmed Adis Mirel , Bhardwaj Mohit , Verma Preeti , Arya Damini
Published: July 2024

Agriculture and livestock are fundamental to the economies of developing countries. A substantial portion of crop harvests is allocated for animal feed. Thus, more technological advancements are necessary to enhance agricultural productivity and provide affordable feed. Future biotech crops are expected to play a crucial role in this area. The goal is often to introduce traits into plants that do not naturally occur in these species. These new traits may include resistance to pests, diseases, or environmental conditions, or the production of specific nutrients or pharmaceutical agents. GM crops have indirectly benefited the livestock sector by increasing the yield of feed ingredients and improving quality traits. These crops are primarily used in livestock feed rations as energy and/or protein sources. Numerous animal feeding studies have been conducted to demonstrate that genetically modified crops are as nutritious and wholesome as compared to their conventional counterparts. No biological relevant differences in animal performance, health, or animal product (meat and milk) composition had been observed in various studies conducted. Overall, no significant differences in gain, intake, and feed conversion have been reported.  Since the GM crop’s composition is not different from its conventional counterpart [except for the introduced transgene(s) and expressed protein(s)] and the expressed transgenic protein is rapidly digested in the digestive system, one would not expect any unintended effects. The introduction of genetically modified (GM) crops into the market undergoes extensive testing and a rigorous approval process to ensure food, feed, and environmental safety. This process includes thorough analyses before GM crops are deemed safe for commercial use. GM livestock feed is assessed for its nutritional composition and digestibility by comparing it with conventional crops. Therefore, while GM crops have the potential to enhance the efficiency of animal agriculture by improving nutritional content, reducing pesticide use, and increasing crop yields, it is essential to approach their adoption with caution.