bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Foreign Aid and Remittances Flows on Saving and Investment in Developing South Asia: Panel Data Study
Authors: Ahasan Ul Haque Md. , Kibria Md. Golam , Muhaiminul Islam Selim Md.
Published: April 2021

In this study, we investigate the impact of remittances and foreign aid (official foreign assistance) on investment and saving in South Asian countries. We also analyze the comparative influence of remittances and foreign aid in stimulating saving and investment. We use a sample of five South Asian countries over the period 1985-2018 and employ OLS and 2SLS methods to estimate the effect of remittance and foreign aid on saving and investment. The result reveals that remittance has a positive impact on saving but has no significant effect on investment and shows that foreign aid has no significant impact on saving but negatively influences investment. In line with our results, a rise in 10 percent of remittances in South Asia raises savings by 1.6 percent in the OLS estimates and by 1.7 percent when we use 2SLS. At the same time for a 10% increase in foreign aid decreases saving by 4.3% and 3.3%, respectively, in two methods. For the second regression, an increase in 10% remittances hamper investment by 1.3% and 1% for OLS and 2SLS, respectively. And for the analogous 10% increase in foreign aid decrease investment by 5.4% and 5.2%, respectively. However, if foreign aid is efficiently used, it can be an important complement to remittances by permitting households to overcome the minimum threshold level and they can use a bigger portion of their remittances for savings and investment motive.
The Elephant in the Room: Examining the Connections between Humility and Social Status
Authors: Michalec Barret , Piemonte Nicole , Hafferty Frederic W.
Published: April 2021

Humility is most frequently discussed as a socially-valuable trait, and being perceived as humble is generally considered beneficial.  Although there has been extensive scholarship expounding the concept of humility, previous work has yet to fully examine the role(s) of social status and stratification in regards to the perception of others’ humility and being humble.  In this sense, there is an elephant in the room that must be acknowledged in order to advance humility theory.  In this paper, we provide brief overviews of humility, social status and stratification, and utilize expectation states theory as a flashlight to explore the potential connections between humility and social status from a more sociological perspective. We then showcase where the “elephant” may be hiding in the humility literature (focusing specifically on race and gender), attempting to shed light on potential next steps for future research
PERTUMBUHAN DAN PRODUKSI BEBERAPA VARIETAS TANAMAN JAGUNG (Zea mays l.) DENGAN PEMBERIAN BERBAGAI DOSIS PUPUK ORGANIK CAIR DAN PUPUK KANDANG
Authors: Hatta Muh. , Saida Saida , Haris Abdul
Published: April 2021

This research aims to determine the effect of varieties and fertilization combinations between liquid organic fertilizer and manure and the interaction of both that provide the best growth and production. This research was carried out in the Religion Agro Tourism garden in Padanglampe Village, Ma'rang District, Pangkajene Regency and the Islands of South Sulawesi Province, from January to May 2020. The experimental design used was a split plot design with two factors, namely variety and a combination of liquid organic fertilizer with manure, variety as the main factor consisted of three levels, namely BISI-18 variety, NASA29 variety and Pertiwi-5 variety. The combination of liquid organic fertilizer with manure as a plot consists of four levels, namely Control, a combination of liquid organic fertilizer with chicken manure, a combination of liquid organic fertilizer with cow manure, a combination of liquid organic fertilizer with manure and cow manure . Data were analyzed by variance using the F Test. The difference in the mean value of the treatment would be tested with Tukey's HSD (honestly significant difference) test at the 0.05% level.The results showed that (1) The treatment of three varieties did not significantly affect all observed parameters. But the Pertiwi-5 variety tends to be the best compared to other varieties. (2) The treatment of fertilizer combination between liquid organic fertilizer and manure significantly influences all of the monitoring parameters. The combination of liquid organic fertilizer 5cc / l. Water with Chicken manure 15 tons / ha and Cow manure 15 tons / ha tend to have a pretty good effect, by showing the dry shell weight per hectare of 8.75 tons / ha. (3) The interaction between varieties with a combination of liquid organic fertilizer and manure does not significantly affect all observation parameters. But the interaction between Pertiwi-5 varieties with a combination of liquid organic fertilizer 5cc / l. Water with Chicken manure 15 tons / ha and Cow manure 15 tons / ha tend to be the best compared to other interactions
Implementasi Algoritma Goverment Standard (GOST) dalam Pengamanan File Dokumen
Authors: Sugiarti Sugiarti , Mirnawati
Published: April 2021

Dokumentasi dalam teknologi saat ini adalah hal yang tak dapat terlepas dari kebutuhan suatu lembaga atau instansi dimana dokumen adalah hal yang paling sering digunakan baik dalam bentuk dokumen manual maupun dalam bentuk file teks dalam komputer. Oleh karena itu,.keamanan data atau dokumen rahasia sangat dibutuhkan dalam bisnis maupun pribadi. Tetapi dalam pengiriman atau pengamanan file data yang bersifat rahasia masih kurang dalam sistem keamanan data. Maka dari itu perlu keamanan tambahan untuk proses penyimpanan file baik itu file yang di rasa pribadi maupun data dalam keorganisasian dengan menggunakan proses enkripsi dan deskripsi menggunakan metode Government Standard (GOST). Maka data penting dapat lebih terjaga dan dengan adanya aplikasi ini kita dapat mengenkripsi data untuk menjaga kerahasiaan file yang kita simpan. Aplikasi ini dibangun dengan menggunakan Visual Studio 2010.
Славетні традиції Київського вищого військового авіаційного інженерного училища
Authors: Салій А.Г, , Коротін С.М, , Радько О.В.
Published: April 2021

У статті проведено ретроспективний аналіз славетного шляху, пройденого Київським вищим військовим авіаційним інженерним училищем (далі — КВВАІУ), та його значного вкладу у формуванні багатьох поколінь висококваліфікованих авіаційних інженерів-професіоналів для їх самовідданої служби у лавах авіації Збройних Сил України. Наведені цікаві факти щодо основних етапів формування училища, змін у його керівництві, структурі, завданнях та видатних особистостей. Показано, що натепер правонаступником славетного вишу є Інститут авіації та протиповітряної оборони Національного університету оборони України імені Івана Черняховського, який уособлює собою спадкоємність поколінь і гідно продовжує почесну справу підготовки високопрофесійного кадрового резерву військових інженерів-авіаторів.

Ключові слова: захисник Батьківщини, КВВАІУ, історичний шлях, авіаційний інженер, традиції
Військово-історичний музей — реальна частина буття Національного університету оборони України імені Івана Черняховського
Authors: Сегеда С.П. , Андріяко А.М.
Published: April 2021

Національний університет оборони України імені Івана Черняховського (НУОУ) — вищий військовий навчальний заклад, що має унікальні експонати в колекції свого військово-історичного музею. Тут знаходяться особисті речі людей, які працювали та навчалися в університеті. А також холодна і вогнепальна зброя, військова техніка часів Другої світової війни та сучасності. Кожен експонат музею має власну унікальну історію. Керівниками музею НУОУ були полковник запасу І. М. Мешков (1992–2006), підполковник С. М. Іваненко (2006–2008), полковник А. М. Андріяко (2008–2014), працівник Збройних Сил М. О. Ткаченко (з 2014 і по теперішній час). Серед експонатів музею є 592 унікальних світлини, на яких зафіксовано життєдіяльність університету з часів його заснування як військової освітньо-наукової установи до сьогодення. У Книзі почесних гостей музею залишили захопливі відгуки міністри оборони, начальники генеральних штабів України та зарубіжжя, представники українських та закордонних військових навчальних закладів, мери міст України, відомі політики. Нині з військовою історією Національного університету оборони України імені Івана Черняховського, яку ілюструють експонати музею, мають можливість ознайомитися відвідувачі з усієї України, іноземні делегації, що бувають із візитами у Національному університеті оборони України імені Івана Черняховського, молодь та школярі Києва.
Ключові слова: військово-історичний музей, колекція, вогнепальна зброя, холодна зброя, експозиція.
Numerical Evaluation of Slender Glass Panel with Complex Geometry Subjected to Static Load and Soft-body Impact
Authors: Kozłowski Marcin
Published: April 2021

Current standards and glass codes of design practice require that glazing used in architectural applications has to be resistant to, in addition to typical loads, also accidental events, in particular human impact, without showing damage that is disproportionate to the original cause. A case study was performed of an indoor glass lantern in a public building made from slender two-side supported glass panels with a complex geometry (36 ventilation holes). The paper provides structural assessments and results of in-situ experiments including static loading and soft body impact. Results from numerical simulations of impact loading on the glass panels complementing the experimental results are also presented.
高温空气燃烧技术在隧道窑中的应用研究
Authors: 张 闯
Published: April 2021

高温空气燃烧技术的应用，不仅可以提升工业炉内部的燃烧效率，而且可以减少污染物的排放。燃烧的温度越高，产生的热量越多，说明燃烧的越充分。窑内的温度越高，烟气中CO、CxHy、H2的含量也会大大增加，之后降低，循环这样的过程。文章围绕高温空气燃烧技术，论述隧道窑中燃烧技术的应用，并提出相应的改造措施，仅供参考。
市政工程施工中的安全管理与质量控制
Authors: 张 永辉 , 朱 小永
Published: April 2021

近年来，我国综合国力在多方面利好因素的影响下得到了显著的发展进步，从而为我国城市建设工作的全面实施创造了良好的基础，在这种发展形势下，各个地区大量的新兴市政工程项目应时而生。在实际组织实施市政工程建设施工工作的过程中，为了从根本上对工程施工质量加以保证，那么最为重要的就是需要全面的落实工程施工安全管理和质量控制工作，合理的运用最先进的施工质量控制以及安全管理理念，促进市政工程各项施工工作有序高效的开展。这篇文章主要针对市政工程施工过程中安全管理与质量控制工作展开全面深入的研究分析，希望能够对我国城市建设工作的良好发展有所帮助。
地铁机电安装工程造价的影响因素分析与控制措施
Authors: 李 凯
Published: April 2021

近年来，我国社会经济水平得到了快速的提升，从而为地铁工程行业的发展起到了良好的推动作用。在地铁工程项目之中机电安装工程的作用是非常巨大的，并且涉及到的工程量较多，所以机电安装工程的施工效率与整个地铁工程施工质量和施工安全存在密切的关联，要想保证地铁机电安装工程整体质量和效率，最为重要的就是积极的落实工程造价管理工作，针对与工程造价存在关联的因素进行综合分析，针对其中的问题制定出有效的解决方案。就机电安装工程来说，各项工作的实施务必要对安全性加以重点关注，但是就整个机电工程安装工程来看，经常会出现预算与实际花费不一致的情况，工程成本超预算的问题十分的严重。对于上述问题往往是由于人为因素和自然因素造成的，所以我们可以从这两个方面入手来加以切实的把控。
电力工程技术问题及施工安全研究
Authors: 赵 娜
Published: April 2021

在当前时期，国内经济呈现出良好的发展趋势，城市规模也随之扩大，然而电力工程却呈现出发展停滞的状态，这就使得社会需求难以得到满足。如果电力工程存在的问题未能消除的话，电力系统发生故障的几率则会明显增加，这就使得供电无法保证稳定，而且安全性也会明显降低。在电力系统当中，配电网是十分关键的，其对供电质量会产生直接影响，因而要对配电网予以有效管控，这样方可使得电力系统保持良好的运行状态。
浅谈透镜天线在5G网络覆盖中的应用
Authors: 李 东耀
Published: April 2021

随着5G终端直连技术D2D的发展，毫米波在大规模物联网、无人驾驶中的广泛应用，将有助于推动毫米波网络快速部署，为解决毫米波在无线通信中的不足，透镜天线将在无线网部署中广泛应用。
浅析高速公路隧道机电设施养护检测技术
Authors: 钱 珊珊
Published: April 2021

在社会快速发展的影响下，我国高速公路工程行业得以全面的进步发展。在高速公路工程结构中，隧道结构的作用是十分巨大的，要想从根本上确保高速公路隧道工程整体质量，那么最为重要的就是需要充分结合各方面实际情况，针对隧道机电设施进行切实的管理，选择利用最先进的养护检测技术对于机电设施进行检测，对于其中所存在的问题进行及时的解决，尽可能的避免危险隐患的发生。高速公路隧道机电系统通常都是由监控系统、通信系统和照明系统、通风系统、消防系统等组成，其中监控系统以及照明系统在隧道安全保障中的作用非常巨大。高速公路交通量较大，极易遭到外界环境不良因素的影响，通信整体效果不佳，这些问题都会对高速公路隧道机电设施养护检测的实施产生一定的限制。隧道机电设施组成结构较为复杂，这样就对管理工作的整体水平提出了更高的要求，为了切实的对管理工作的效率和效果加以保证，那么最为重要的就是需要制定切实可行的管理制度，并及时对隧道机电设施加以专业的养护检测，从而确保高速公路隧道工程的整体稳定性和安全性。针对高速公路隧道监控系统以及照明系统实施养护检测工作，能够高效的判断和解决隧道机电设施中所存在的各种问题以及危险隐患，确保隧道机电设施的整体使用效果。
关于电梯定期检验中限速器安全钳联动机构故障的探讨
Authors: 李 煜 , 叶 辉
Published: April 2021

限速器安全钳属于电梯核心构件，在电梯服役阶段发挥着重要作用，可以保证电梯运行平稳，极大限度提高电梯安全性以及使用效率，作用十分显著。在电梯服役期间，电梯定期检验是基本保障，作为必不可少的工作，在检验期间，如果发现运行故障，要通过针对性、专业性故障处理，将隐患排除，提高电梯的安全系数。文章将安全钳联动机构为例,重点分析其故障原理以及相关处理措施，以便提升电梯运行质量。
Relationship between Thickness of Early Oral Tongue Carcinoma (T1, T2) with Cervical Lymph Node Metastasis
Authors: Razzak Md Abdur , Siddique Belayat Hossain , Islam Azharul , Haque Md Hasanul , Sattar Md Abdus , Razib Sayed Farhan Ali , Abdullah Effat Zahan , Jewel Arif Mahmud , Sayied Md Jaber Al , Md Quamruzzaman -
Published: April 2021

Background: Carcinoma of oral tongue is the most common oral cancer and because of its structure and function is prone for early local and regional spread of cancer. The final outcome of a primary tongue carcinoma patient depends upon various prognostic factors like thickness of tumor, depth of invasion, size of lesion and neck node 67metastasis. Risk of metastasis and spread to neck nodes increases with increase in tumor thickness
Methods: This prospective observational study was carried out in the Department of Otolayngology- Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka for 18 months. Thirty patients with early oral tongue carcinoma i.e.T1 & T2 as per UICC and AJC criteria were included in this study by purposive non-randomized sampling technique. Result of the study were expressed as mean, standard deviation (+SD), frequency and percentages. Unpaired Student’s t-test and Pearson’s correlation co-efficient (r) test were performed.
Results: Result of the study showed the mean (+SD) thickness of the tumor was 3.62 (+1.46) mm. Minimum thickness 1.1mm and maximum thickness 7.8mm. Only 21 (70%) subjects neck node were metastasized from tongue and mean (+SD) tumor thickness of the positive neck node metastasis was 5.54 (+1.07) mm and negative neck node metastasis was 2.87 (+0.75) mm. This indicated a significant difference between the groups. Pearson’s correlation co-efficient r (+0.981) which indicated tumor thickness was positively correlated with neck node metastasis.
Conclusion: Tumor thickness of the early oral carcinoma positively correlated with neck node metastasis. Correlation between thickness and metastatic lymph node can help planning the treatment regimen and indicate the disease prognosis.
Bangladesh J Otorhinolaryngol; April 2021; 27(1): 25-35
Outcome of Interlay Type 1 Tympanoplasty for Large Central Perforation
Authors: Huq Md Mahmudul , Qaiyoum SM Mostofa , Mannan Md Saifullah Ibne , Md Kamruzzaman -
Published: April 2021

Background: Perforation of the tympanic membrane may occur from various reasons. Most of these perforations heal spontaneously, whereas the remaining long-standing perforations that lead to recurrent ear discharge need tympanoplasty. Interlay Type 1 Tympanoplasty,a newer technique has shown promising results with higher success ratein terms of hearing gain and graft uptake.
Objective: To analyze the results of interlay Type 1 Tympanoplasty in terms of graft uptake and hearing improvement in cases of inactive mucosal chronic otitis media (COM) with large central perforation.
Methods: This is a prospective study of 24 months (January 2018 to December 2019) duration conducted in department of E.N.T, Khulna medical college, Khulna and data was collected from the 60 patients admitted for tympanoplasty. Results were calculated in terms of graft accepted or rejected and decrease in air bone gap.
Result: The graft uptake rate in the present study was found to be 91.67% and the patients reported an improvement in terms of hearing. Pre operatively mean air bone gap was 26.5dBand post operatively after 12 weeks mean air bone gap improved to 17.58dB.
Conclusion: Interlay Type 1 Tympanoplasty is an effective technique over conventional methods in terms of both graft uptake as well as hearing improvement in large central perforation.
Bangladesh J Otorhinolaryngol; April 2021; 27(1): 86-91
Congenital Cholesteatoma in Adult: Is it Still Possible?
Authors: Tan Heng Yao , Idris Anuar Idwan , Ong Cheng Ai , A Asma
Published: April 2021

Congenital cholesteatoma is a mass of squamous epithelium located medial to an intact tympanic membrane without previous history of tympanic membrane perforation, otorrhoea or otological surgery. We described a 24 year old gentleman with a left postauricular discharging fistula for 3 years with recent history of gradual hearing loss, tinnitus and recurrent episodes of positional vertigo. Clinical examination noted left postauricular fistula opening and otoscopy showed a whitish mass medial to a bulging intact tympanic membrane. High-resolution computed tomography of temporal bone was suggestive of cholesteatoma. Left modified radical mastoidectomy was done and he recovered with resolution of symptoms.
Bangladesh J Otorhinolaryngol; April 2021; 27(1): 96-99
Therapeutic Efficacy of Bacteriophage Therapy to Treat Carbapenem Resistant Klebsiella Pneumoniae in Mouse Model
Authors: Dhungana Gunaraj , Regmi Madhav , Paudel Prashant , Parajuli Apsara , Upadhyay Elisha , Gyawali Indu , Upreti Himani , Nepal Roshan , Pradhan Pragati , Malla Rajani
Published: April 2021

Background: Global emergence of carbapenem-resistant Klebsiella pneumoniae is a major public health concern. Phage therapy – application of lytic phage to kill pathogenic bacteria – is considered as one of the promising alternatives to tackle this antibiotic crisis in recent days. This study aimed to isolate, characterize and evaluate therapeutic efficacy of a novel K. pneumoniae phage in mouse model.Methods: A novel lytic bacteriophage (phage) Kp_Pokalde_002 was isolated against carbapenem-resistant K. pneumoniae (Kp56) and characterized. Safety parameters of the phage were evaluated by bioinformatic analysis of its genome. A lethal dose (~1×107 CFU/mouse) of Kp56 was determined and administrated in the mice. The infected mice were treated with phage Kp_Pokalde_002 at a multiplicity of infection (MOI) 1.0 (~1×107 PFU/mouse) via both oral and intraperitoneal (IP) routes.Results: Isolated phage comprised an icosahedral capsid with a short tail. Based on genome analysis, the phage was strictly lytic belonging the Podoviridae family (T7-like viruses) and free from any virulent and antibiotic-resistant genes. The phage was stable up to 60 °C for 30 minutes and effective between pH 4 to 11 (optimum pH 9). The phage exhibited a short latent period (20 minutes) with burst size of 121 phage particles per infected cell. The infected mice were rescued with the phage therapy via both oral and IP route. Significant reduction of bacterial load (3-7 log10 CFU/ml) in the blood and lung was observed in the treatment group.Conclusions: We provide an evidence of successful phage therapy against carbapenem-resistant K. pneumoniae infected mouse model using locally isolated lytic phage.Keywords: Bacteriophage; klebsiella pneumonia; phage therapy
Identifikasi Citra Digital Kura-Kura Sumatera Dengan Perbandingan Ekstraksi Fitur GLCM Dan GLRLM Berbasis Web
Authors: Sari Julia Purnama , Erlansari Aan , Purwandari Endina Putri
Published: April 2021

Kura-kura merupakan hewan yang sangat mudah dikenali karena mempunyai bentuk tubuh yang khas. Ciri khas yang dimiliki oleh kura-kura adalah adanya karapaks yang sering disebut dengan cangkang. Dalam mengidentifikasi kura-kura tidak bisa sembarangan, dibutuhkan seorang pakar yang benar-benar paham dengan spesies tersebut. Identifikasi keanekaragaman spesies kura-kura sumatera melalui pengolahan citra digital ini menggunakan metode ekstraksi fitur tekstur  berbasis website.  Salah satu cara mengidentifikasi jenis kura-kura yaitu dengan menggunakan sistem identifikasi secara otomatis berbasis pemrosesan citra digital. Pada penelitian ini dilakukan perbandingan dua ekstraksi ciri yaitu Gray Level Co-Occurrence Matrix (GLCM) dan Gray Level Run Length Matrix (GLRLM). Ekstraksi ciri GLCM dan GLRLM yang dilakukan pada penelitian ini menggunakan sudut 0°, 45°, 90°, 135°. Hasil Penelitian menunjukkan bahwa hasil akurasi identifikasi dengan menggunakan ekstraksi ciri GLRLM lebih baik dibandingkan GLCM. Hasil Akurasi tertinggi pada GLRLM 79,5% sementara dengan GLCM menghasilkan akurasi sebesar 75%.Kata Kunci: Identifikasi, Kura-kura, Karapaks, Gray Level Run length Matrix, Gray Level Co-Occurrence Matrix.
Pengendalian Internal terhadap Penerimaan Negara Bukan Pajak (PNBP) melalui Penerapan Peraturan Pemerintah Republik Indonesia Nomor 46 Tahun 2002 pada Kantor Wilayah Badan Pertanahan Nasional (BPN) Sumatera Utara
Authors: Khairunnida Khairunnida , Naipospos Nova Yessyca
Published: April 2021

Pembahasan tentang pengaruh partisipasi anggaran dengan senjangan anggaran masih menunjukkan ketidakkonsistenan sehingga hasil yang diperoleh bertentangan. Perbedaan hasil penelitian dapat diselesaikan melalui pendekatan kontijensi dengan menggunakan  variabel moderasi. Penelitian ini bertujuan untuk membuktikan pengaruh komitmen organisasi sebagai variabel moderasi terhadap hubungan antara partisipasi anggaran dengan senjangan anggaran.Objek penelitian adalah manajer dan staff yang terlibat dalam proses penyusunan anggaran (40 responden)Periode 2016 . Data dikumpulkan dengan menggunakan kuesioner, enam item untuk partisipasi anggaran sebagai variabel bebas, enam item untuk senjangan anggaran sebagai variabel terikat, dan sembilan item  untuk komitmen organisasi sebagai variabel moderasi. Model analisis yang digunakan adalah regresi linear sederhana untuk hipotesis pertama dan analisis regresi moderat untuk hipotesis kedua.Penelitian ini menghasilkan dua penemuan sebagaimana yang diajukan dalam hipotesis penelitian. Pertama, partisipasi anggaran berpengaruh terhadap senjangan anggaran. Kedua, komitmen organisasi tidak mempunyai pengaruh terhadap hubungan antara partisipasi anggaran dengan senjangan anggaran.
Pengaruh Anggaran Kas sebagai Alat Perencanaan dan Pengendalian Terhadap Tingkat Likuiditas Pada Toko Kue Dapur Amien
Authors: Ariany Vince , Sintia Sinta
Published: April 2021

The purpose of this study was to determine the effect of the cash budget, as a planning and control tool on the level of liquidity in the Amien Kitchen Cake Shop. This research uses descriptive qualitative method. Analysis is done by collecting data and analyzing how to use the cash budget to make comparisons between theory and practice and set forth to explain an explanation of the numbers and then explained again in the form of prose or standard language description. The results of this study accept that the cash budget as a planning tool and cash budget as a control tool together have a significant influence on the level of liquidity.
KONFLIK PERAN GANDA PADA WANITA KARIER
Authors: Rahmayati T. Elfira
Published: April 2021

Dalam menjalankan karier, wanita dituntut untuk menjalankan pekerjaan secara professional dengan segala tanggung jawabnya. Namun bagi wanita karier yang telah menikah tuntutan urusan rumah tangga, mengurus pasangan, anak dan juga urusan rumah tangga lainnya  menjadi tanggung jawab yang tidak dapat dipisahkan. Dengan dua tanggung jawab tersebut wanita karier harus mampu menyeimbangkan antara urusan rumah tangga maupun urusan pekerjaan sehingga dapat meminimalisir konflik peran ganda. Sifat penelitian ini adalah deskriptif-anal­itik, Teknik pengumpu­lan data dengan dokumentasi. Penelitian ini merupakan penelitian kepustakaan tentang konflik-konflik yang timbul pada wanita karier. Teknik analisis data dalam penelitian ini menggunakan content analysis. Hasil dari penelitian ini menunjukkan wanita karier  dengan peran ganda mengalami konflik. konflik yang terjadi pada wanita karier diantaranya ada tumpang tindih antara tugas pekerjaan dengan tugas rumah tangga. Dalam  tugas  ibu rumah tangga tuntutan keluarga ber­hubungan dengan waktu yang dibu­tuhkan untuk menangani pekerjaan atau tanggung jawab di dalam rumah tangga, menjaga anak, atau mengu­rus orang tua. Sedangkan tuntutan di dalam karier (pekerjaan) berkaitan dengan tekanan yang berasal dari be­ban kerja yang berlebihan dan wak­tu.

Kata Kunci : Konflik Peran Ganda, Wanita Karier
PENGARUH JARAK TANAM DAN KEDALAMAN LUBANG TANAM TERHADAP PERTUMBUHAN DAN PRODUKSI JAGUNG MANIS (Zea mays saccharata Sturt.)
Authors: Purba Eliakim Purba
Published: April 2021

Tujuan penelitian untuk mengetahui respon pertumbuhan dan produksi jagung manis (Zea mays saccharata Sturt.) pada berbagai jarak tanam dan kedalaman lubang tanam. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) faktorial yang terdiri dari dua faktor yaitu : Faktor pertama jarak tanam dengan notasi (J) yang terdiri dari 3 taraf yaitu: J1 = 70 x 30 cm, J2 = 70 x 40 cm, dan J3 = 70 x 50 cm. Faktor kedua kedalaman lubang tanam dengan notasi (K) yang terdiri dari 4 taraf yaitu : K1 = 3 cm, K2 = 5 cm, K3 = 7 cm, dan K4 = 9 cm. Parameter yang diamati yaitu tinggi tanaman (cm), diameter pangkal batang (mm), berat tongkol berkelobot per tanaman (g), berat tongkol tanpa kelobot per tanaman (g), panjang tongkol (cm), dan produksi per plot (kg). Hasil penelitian menunjukkan bahwa interaksi antara jarak tanam dan kedalaman lubang tanam memberikan respon yang nyata terhadap parameter tinggi tanaman umur 30 HST. Kombinasi perlakuan terbaik yaitu J3K2 (jarak tanam 70 x 50 cm dan kedalaman lubang tanam 5 cm. Hasil penelitian menunjukkan produksi tanaman jagung manis yang tertinggi yaitu menggunakan jarak tanam 70 x 30 cm dengan kedalaman lubang tanam 5 cm yang dilakukan secara bersamaan.

 

Kata Kunci : Jarak Tanam, Kedalaman Lubang Tanam, Jagung Manis (Zea mays)
FAKTOR-FAKTOR YANG MEMPENGARUHI JUMLAH KUNJUNGAN WISATAWAN DI PROPINSI SUMATERA UTARA
Authors: Rosmika Enita
Published: April 2021

Tourism Product Knowledge is regarding the general knowledge of all regions in Indonesia which includes the location of the region / geography, climate, history, politics, culture, and particularly object - attractions and facilities and attractions which support it. In this study, entitled Factors Affecting Total tourist arrivals in Sumut Province Year Period 2014 -2019. The purpose of this study was to determine the number of rooms and the dollar exchange rate partially and simultaneously inuence the number of tourist arrivals in Sumut, in order to obtain a result the number of hotel rooms inuential not evident partially on the number of tourists visiting the province of Sumut, because t smaller than t table or -1.651 <1.761 while the dollar exchange rate has a signicant effect on the number of tourists visiting the province of Sumut, because t is greater than t table or 2.236> 1.740 and Total Room and the US dollar exchange rate simultaneously or together of the number of tourists visiting Sumut Province since F count> F table or 13.288> 3.59. The magnitude of the effect of independent variables on the dependent variable simultaneously can be known from the value of the coefcient of determination (R2) is equal to 0.639. This means that both variables jointly contribute to or inuence amounted to 63.9 percent of the number of tourists visiting the province of Sumut, while the remaining 36.1 percent is inuenced by other variables that are not described in the model, such as safety, service, facilities.
ASPEK HUKUM PENYELESAIAN SENGKETA SECARA MEDIASI TERHADAP KONFLIK ANTARA NASABAH DENGAN PIHAK BANK
Authors: Deliani Deliani
Published: April 2021

Penambahan cabang-cabang Bank dan pelayanan bank telah telah menjangkau sektor pedesaan dan masyarakat didorong untuk membuka rekening sekecil apapun. Dalam rangka menarik minat nasabah untuk menyimpan dana dalam bank, beberapa bank mengadkan undian , menawarkan hadiah-hadiah, mempromosikan iklan-iklan yang lihai , menawarkan bunga dan biaya-biaya yang lebih menarik. Kegiatan penghimpunan dana bagi bank pada masyarakat itu meliputi transaksi-transaksi dalam pemberian kredit , pemanfaatan sarana –sarana dan fasilitas bank seperti penyediaan kartu kredit, ATM, surat-surat berharga dan lain-lain. Dari pemaparan diatas , maka jelaslah bahwa kedudukan bank adalah sebagai lembaga yang berhubungan erat dengan masyarakat dan mempunyai hubungan intermediasi dengan masyarakat itu sendiri. Dalam perspektif Undang-Undang Nomor 8 Tahun 1999 tentang perlindungan konsumen yang telah diatur dalam pasal 4 Undang-Undang Perlindungan Konsumen yang mengatur mengenai hak dan kewajiban konsumen , baik perjanjian simpanan maupun perjanjian kredit, kedudukan nasabah bank merupakan konsumen yang harus memperoleh perlindungan hukum. Perlindungan hukum bagi nasabah bank seharusnya sudah dilakukan pada tahap pra-perjanjian sampai dengan pelaksanaan perjanjian . Ketika hubungan hukun antar Bank dengan nasabah mulai tercipta, maka sejak itu terbuka kemungkinan sengketa antara pihak . Penyelesaian sengketa antar pihak tersebut dapat dilakukan melalui proses litigasi dan non litigasi.
PENGARUH PERTUMBUHAN PENDUDUK TERHADAP PERTUMBUHAN EKONOMI
Authors: Azulaidin Azulaidin
Published: April 2021

Untuk mengetahui pengelolaan pertumbuhan ekonomi dibutuhkan pengetahuan tentang analisis perkembangan beberapa indikator makro ekonomi seperti pengangguran, tingkat Inflasi, dan pertumbuhan penduduk. Dimana Peningkatan pengangguran, tingkat Inflasi dan pertumbuhan penduduk ini dapat menentukan tingkat pertumbuhan ekonomi suatu wilayah. pertumbuhan penduduk dan Inflasi tidak berpengaruh terhadap pertumbuhan ekonomi karena pertumbuhan penduduk dengan kapasitas baik akan meningkatkan jumlah produksi dan penyerapan akan hasil produksi juga akan meningkat seiring banyaknya jumlah penduduk yang ada. Sehingga perputaran ekonomi akan berjalan dengan lancar dengan tujuan pertumbuhan ekonomi menjadi tidak terhambat. Pertumbuhan penduduk adalah sebuah proses keseimbangan yang dinamis antara komponen kependudukan yang dapat menambah dan mengurangi jumlah penduduk. Pertumbuhan Ekonomi terutama pertumbuhan ekonomi wilayah adalah pertambahan pendapatan masyarakat secara keseluruhan yang terjadi di wilayah tersebut, yaitu kenaikan seluruh nilai tambah (added value) yang terjadi.
İşsizlerde Yaşam Doyumunu Etkileyen Faktörlerin İncelenmesi: Dünya Değerler Araştırması Verisinden Türkiye Analizi
Authors: Hatipoğlu Ertuğrul , Tuncay Tarık
Published: April 2021

Bu çalışma işsizlerin sosyo-demografik özellikleri ve yaşadıkları hane özellikleri ile yaşam doyumu düzeyleri arasındaki ilişkiyi incelemeyi amaçlamaktadır. Araştırma nicel araştırma deseninde kesitsel tarama yönteminde yürütülen Dünya Değerler Araştırmasının dört (2001-2007-2011-2018) dalgasından elde edilen verilerin analizi ile gerçekleştirilmiştir. Araştırmanın çalışma grubunda 650 işsiz yer almaktadır. Araştırma sonuçlarına göre, işsizlerin cinsiyet ve eğitim düzeylerine göre yaşam doyumu puanları fark oluşturmamaktadır. İşsizler arasında orta yaş grubundaki ve medeni durumuna göre evli olanların yaşam doyumu puanları daha düşüktür. Bireylerin gelir düzeyi ve algılanan sağlık ile yaşam doyumu puanları arasında pozitif korelasyon tespit edilmiştir. Sahip olunan çocuk sayısı arttıkça ve algılanan sosyal sınıf düştükçe yaşam doyumu puanları azalmaktadır. Araştırmanın bulguları işsizlere yönelik psikososyal destek hizmetlerinin içeriğine katkı vermesi beklenmektedir.
Daz ve Dazlak Sözcükleri Hakkında
Authors: ÇELİK Anıl
Published: April 2021

Türkçede anlam genişletici ya da anlam değiştirici kimi eklerle muhtelif şekillerde teşekkül etmiş olmalarına karşın taban anlamlarına geri dönen ve “döngülü sözcükler” olarak adlandırılabilecek kimi sözcükler vardır. Bu türden sözcüklerin geçirdikleri süreç “anlamsal döngü” olarak adlandırılabilir. “daz ⇔ dazlak” eklemlenmesinde de anlamsal döngü süreci başlamıştır. “Dazlak” sözcüğü tabanı olan “daz” sözcüğüyle aynı anlamda kullanılabilmektedir ve “daz” sözcüğünün dildeki kullanımını sınırlasa da onu kullanımdan henüz tamamıyla düşürmemiştir. Dolayısıyla döngü sürecinin devam ettiği söylenebilir. Bu çalışmada söz konusu anlamsal döngü sürecinin işleyişini ve sebeplerini anlayabilmek adına “daz” ve “dazlak” sözcüklerinin etimolojilerine değinilmiş, bu sözcüklerin Türkçenin tarihî kaynaklarındaki durumlarına göz atılmış, ölçünlü Türkiye Türkçesi, Türkiye Türkçesi ağızları ve çağdaş Türk lehçelerindeki kullanımları örneklendirilmiş, elde edilen bilgilerden yola çıkılarak anlamsal döngüler ile ilgili birtakım çıkarımlarda bulunulmuştur. Araştırmanın, ilgili sözcüklere dair tartışmaları ve çözümlemeleri ortaya koyması, “+lAk” ekinin “türetme” işlevinden ayrılan “genişletme” işlevini dikkate sunması ve genişletme eklerinin “anlamsal döngülerin” ortaya çıkışındaki rolünü bu yolla örneklendirmesi açısından alana katkı vermesi hedeflenmektedir.
Development of Datura metel in different pot sizes
Authors: Pessoa Angela Maria dos Santos , Rêgo Elizanilda Ramalho do , Silva Geovana Priscilla da , Lima Jose Ayron Moraes de , Silva Bruna Regina dos Santos , Rêgo Maílson Monteiro do
Published: April 2021

Datura metel L. belongs to Solanaceae family and presents medicinal and ornamental potential. The use of D. metel as an ornamental plant is still unexplored, however there is a need to gather more information about this species planting, especially for pot cultivation. This study aimed to verify the effects of different pot sizes in the development of D. metel, in order to enable the use of this species in the potted flower market. The work was conducted in a greenhouse at the Biotechnology Department located at Center of Agricultural Sciences of the Federal University of Paraíba (CCA-UFPB), Areia, PB, Brazil. The experimental design used was completely randomized with 3 treatments (pot sizes: T1 = 0.82 dm3, T2 = 1.55 dm3 e T3 = 3.68 dm3) and 10 replications. The variables analyzed were: plant height, stem diameter, canopy diameter, number of ramifications, leaf length, leaf width, leaf number, flower number, flower length, flower diameter, chrolophyll a e chrolophyll b. The data obtained was submited to analysis of variance and later on clustered based Tukey’s test (5%). All the analyses were made on GENES software. There is variation between treatments for characteristics evaluated. Treatments 2 (1.55dm3) and 3 (3.68dm3) had similar values and the highest mean values for the characteristics of plant height, number of leaves and chlorophyll b. The size of the vase influences the development of the Angel’s trumpet (D. metel). Pot size influences D. metel development. The medium size recipient (1.55 dm3) is recommended for cultivation of D. metel because it presents ideal plant development, such as plant height and number of leaves, for use with ornamental species pots.
Associação entre dieta enteral prescrita versus infundida e desfecho clínico em idosos internados em uma Unidade de Terapia Intensiva
Authors: Araújo Camila Melo de , Carvalho Adriana Gomes Cézar de , Feitosa Gina Araújo Martins , Cabral Caroline Sousa , Barbosa Janine Maciel , Olinto Edcleide Oliveira dos Santos , Silva Juliana Andrade da , Souza Paloma Egídio Andrade de
Published: April 2021

Introdução: O público idoso está em maior risco de desenvolver déficits nutricionais, uma vez que há um comprometimento da função fisiológica. Objetivo: avaliar a associação entre a dieta enteral prescrita versus infundida e o desfecho clínico de pacientes idosos internados em uma Unidade de Terapia Intensiva. Metodologia: O estudo foi seccional, desenvolvido com idosos em Unidade de Terapia Intensiva do Hospital Universitário Lauro Wanderley da Paraíba, onde foram avaliados através de uma ficha de acompanhamento nutricional. Na análise estatística utilizou-se os testes Qui-quadrado assumindo um nível de significância (p<0,05). Resultados: Foram avaliados 79 idosos, sendo a maioria do sexo feminino com 62%, e idade média de 72,5 anos. Quanto às intercorrências da terapia, a sonda nasogástrica aberta foi significativamente associada ao volume infundido versus prescrito não satisfatório. Pacientes cujo volume prescrito versus infundido foi satisfatório estiveram internados por mais de 21 dias. O total de 29 pacientes que tiveram alta hospitalar obteve 69%, no qual, receberam satisfatoriamente o volume prescrito versus infundido. Por outro lado, 21 desses indivíduos apresentaram 63,6% do total de óbitos que estiveram associados ao não atendimento desta variável. Conclusão: Observou-se que pacientes que permaneceram mais dias na UTI tiveram maior volume de dieta infundida alcançando suas metas preconizadas, em virtude daqueles que apresentou alta, notando-se que a maioria recebeu satisfatoriamente volume prescrito versus infundido, uma vez que é necessária a qualidade em terapia nutricional de forma mais ampla na população idosa.
Agro-economic efficiency in radish-arugula intercropping as a function of green manuring and population density
Authors: Sá Jolinda Mércia de , Bezerra Neto Francisco , Queiroga Roberto Cleiton Fernandes de , Chaves Aridênia Peixoto , Lima Jailma Suerda Silva de , Santos Elizangela Cabral dos , Nunes Renato Leandro da Costa , Guerra Natan Medeiros , Porto Vania Christina do Nascimento , Lino Vitor Abel da Silva , Gomes Camile Dutra Lourenço
Published: April 2021

The vegetables intercropping practice triumph in family farming depends on several production factors, including the crops involved, green manuring and plant density of component crops. Therefore, the aim of this work was to assess whether there is agro-economic viability in the radish-arugula intercropping, in different equitable amounts of M. aegyptia and C. procera biomass (20, 35, 50 and 65 t ha-1 on base dry) and in diverse arugula population densities (40, 60, 80 and 100% of that recommended density for single crop - RDSC), combined with 100% of the RDSC for radish in two cropping years. The characteristics, the commercial productivity of radish roots and the arugula green mass yield were evaluated and in the intercropped system, the agronomic indices: land equivalent ratio (LER), intercropping advantage (IA), actual yield loss (AYL), productive efficiency index (PEI), score of the canonical variable (Z), and the economic indicators: gross income (GI), net income (NI), rate of return (RR) and profit margin (PM). The greatest agro-economic advantages of the radish-arugula intercropping were achieved with an LER of 1.64, PEI of 0.86, Z of 1.54, GI of R$ 45,543.92 ha-1, NI of R$ 24,662,31 ha-1, RR of R$ 2.20 for each real invested, and PM of 56.37%, respectively, in the combination of 65 t ha-1 of M. aegyptia and C. procera biomass and arugula population density of 100% of the RDSC, corresponding to the density of 1 million plants per hectare.
Review on the therapeutic activities of the genus Trichilia
Authors: Silva Lusinalva Leonardo da , Almeida Renata de , Silva Fabiana Texeira e , Verícimo Maurício Afonso
Published: April 2021

The genus Trichilia (Meliaceae family) has been attracting interest among Brazilian Flora, due to the biological activities of its secondary metabolites. This genus has species distributed throughout tropical America, recognized for its significant economic importance and high commercial value. Its composition consists mainly of terpenoids (triterpenes, sesquiterpenes, limonoids and steroids) and polyphenols (flavonoids and tannins). In folk medicine this genus is used in preparations such as antimicrobial, antimalarial, antiviral and antioxidant. Studies carried out with several species of the genus Trichilia show that these plants have antioxidant, anticholinesterase, antimicrobial activities against pathogens of great clinical importance, neuroprotective, anti-anaphylactic and anti-inflammatory. In addition, analgesic, antineoplasic, hepatoprotective and immunomodulatory activities have also been investigated and proven in the literature. Based on the great biotechnological potential of the genus Trichilia, from the few studies on its applications in human health and in view of the importance of searching for natural substances that have effective therapeutic activities, this review highlights the main therapeutic applications of species of this genus found in the literature, and stimulate further studies on the use of these plants in the treatment of various diseases. For this, a survey on the topic was carried out in the main sources of scientific research in the period from 2005 to 2020, leading us to conclude that this genus can be a potent ally in the search for new phytotherapic drugs.
Edukasi Penerapan Protokol Kesehatan Sebagai Upaya Pencegahan Penyebaran Covid-19 Pada Penderita Komorbid
Authors: Priya Utama Julvainda Eka
Published: April 2021

Latar Belakang : Corona virus disease-19 atau Covid-19 merupakan penyakit yang dapat disebarkan manusia ke manusia melalui droplet seperti batuk atau bersin, walaupun pola transmisi secara spesifik masih belum diketahui secara pasti. Penyebaran dapat menyebabkan keparahan semakin berat pada penderita penyakit komorbid. Pencegahan penyebaran dapat dilakukan dengan menerapkan protokol kesehatan dan meningkatkan imunitas tubuh melalui edukasi. Tujuan Penelitian : Penelitian ini bertujuan untuk mengidentifikasi pengaruh pemberian Edukasi Penerapan Protokol Kesehatan sebagai Upaya Pencegahan Penyebaran Covid-19 pada penderita komorbid di Wilayah Kerja Puskesmas Kota Semarang. Metode Penelitian : Metode penelitian ini adalah penelitian kuantitatif menggunakan desain quasi experiment dengan pendekatan one group pretest posttest design. Sampel dalam penelitian ini adalah 48 responden penderita komorbid yang diambil dengan teknik consecutive sampling. Pengumpulan data penelitian menggunakan kuesioner google forms. Data dianalisis menggunakan statistik deskriptif  dan Wilcoxon test. Hasil : Hasil penelitian menunjukkan bahwa ada pengaruh edukasi terhadap pengetahuan penyebaran Covid-19 (p= 0,00 < 0,03). Kesimpulan : Berdasarkan hasil penelitian dapat disimpulkan bahwa edukasi berperan penting dalam pencegahan penyebaran Covid-19.
Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection
Authors: Bia D , Barra JG , Armentano RL , Zocalo Y , Pérez H , Saldias M , Alvarez L , Cabrera Fischer EI
Published: April 2021

as Each artery conduces blood (conduit function, CF) and
smoothes out the pulsatility (buffering function, BF), while
keeping its wall protected against the high oscillations of the
pulse waves (damping function, ξ). These functions depend on
each segment viscoelasticity and capability to store and dissipate
energy. When a graft/prosthesis is implanted, the physiological
gradual transition in the viscoelasticity and functionality of
adjacent arterial segments is disrupted. It remains to be
elucidated if the cryografts would allow keeping the physiological
biomechanical transition. The aim of this study was to evaluate
the cryografts capability to reproduce the functional, energetic
and reflection properties of patients’ arteries and fresh
homografts. Common carotid’s pressure, diameter and wallthickness were recorded in vivo (15 patients) and in vitro (15 cryografts and 15 fresh homografts from donors). Calculus: elastic (Epd) and viscous (Vpd) indexes, CF, BF, dissipated (WD)
and stored (WPS) energy and ξ. The graft-patient’s artery
matching was evaluated using the reflection coefficient (Γ) and
reflected power (WΓ). Cryografts did not show differences in
Epd, Vpd, BF, CF, WD, WPS, and ξ, in respect to fresh
homografts and patients’ arteries, ensuring a reduced Γ and WΓ.
Cryografts could be considered as alternatives in arterial
reconstructions since they ensure the gradual transition of
patients’ arteries biomechanical and functional behavior.
Modulation of substance P signaling by dipeptidyl peptidase-IV enzymatic activity in human glioma cell lines
Authors: Bušek P , Stremeňová J , Křepela E , Šedo A
Published: April 2021

Dipeptidyl peptidase-IV (DPP-IV, CD26) is a serine protease
almost ubiquitously expressed on cell surface and present in
body fluids. DPP-IV has been suggested to proteolytically modify
a number of biologically active peptides including substance P
(SP) and the chemokine stromal cell derived factor-1α (SDF-1α,
CXCL12). SP and SDF-1α have been implicated in the regulation
of multiple biological processes and also induce responses that
may be relevant for glioma progression. Both SP and SDF-1α are
signaling through cell surface receptors and use intracellular
calcium as a second messenger. The effect of DPP-IV on
intracellular calcium mobilization mediated by SP and SDF-1α
was monitored in suspension of wild type U373 and DPP-IV
transfected U373DPPIV glioma cells using indicator FURA-2.
Nanomolar concentrations of SP triggered a transient dose
dependent increase in intracellular calcium rendering the cells
refractory to repeated stimulation, while SDF-1α had no
measurable effect. SP signaling in DPP-IV overexpressing
U373DPPIV cells was not substantially different from that in wild
type cells. However, preincubation of SP with the DPP-IV
overexpressing cells lead to the loss of its signaling potential,
which could be prevented with DPP-IV inhibitors. Taken together,
DPP-IV may proteolytically inactivate local mediators involved in
gliomagenesis.
Positioning of the NOR-bearing chromosomes in relation to nucleoli in daughter cells after mitosis
Authors: Kalmárová M , Smirnov E , Kováčik L , Popov A , Raška I
Published: April 2021

It is known that chromosomes occupy non-random positions in
the cell nucleus. However, it is not clear to what extent their
nuclear positions, together with their neighborhood, are
conserved in daughter cells. To address specific aspects of this
problem, we used the model of the chromosomes carrying
ribosomal genes that are organized in clusters termed Nucleolus
Organizer Regions (NORs). We compared the association of
chosen NOR-bearing chromosomes (NOR-chromosomes) with
nucleoli, as well as the numbers of nucleoli, in the pairs of
daughter cells, and established how frequently the daughter cells
had equal numbers of the homologs of certain NORchromosomes associated with individual nucleoli. The daughter
cells typically had different numbers of nucleoli. At the same
time, using immuno-FISH with probes for chromosomes 14 and
15 in HeLa cells, we found that the cell pairs with identical
combinations appeared significantly more frequently than
predicted by the random model. Thus, although the total number
of chromosomes associated with nucleoli is variable, our data
indicate that the position of the NOR-bearing chromosomes in
relation to nucleoli is partly conserved through mitosis.
Sulodexide improves endothelial dysfunction in streptozotocin-induced diabetes in rats
Authors: Kristová V , Líšková S , Sotníková R , Vojtko R , Kurtanský A
Published: April 2021

Diabetes mellitus is associated with many complications including
retinopathy, nephropathy, neuropathy and angiopathy. Increased
cardiovascular risk is accompanied with diabetes-induced
endothelial dysfunction. Pharmacological agents with
endothelium-protective effects may decrease cardiovascular
complications. In present study sulodexide (glycosaminoglycans
composed from heparin-like and dermatan fractions) was chosen
to evaluate its protective properties on endothelial dysfunction in
diabetes. Effect of sulodexide treatment (SLX, 100 UI/kg/day,
i.p.) in 5 and 10 weeks lasting streptozotocin-induced diabetes
(30 mg/kg/day, i.p. administered for three consecutive days) was
investigated. Animals were divided into four groups: control
(injected with saline solution), control-treated with sulodexide
(SLX), diabetic (DM) and diabetic-treated with sulodexide
(DM+SLX). The pre-prandial and postprandial plasma glucose
levels, number of circulating endothelial cells (EC) and
acetylcholine-induced relaxation of isolated aorta and mesenteric
artery were evaluated. Streptozotocin elicited hyperglycemia
irrespective of SLX treatment. Streptozotocin-induced diabetes
enhanced the number of circulating endothelial cells compared to
controls. SLX treatment decreased the number of EC in 10-week
diabetes. Acetylcholine-induced relaxation of mesenteric arteries
was significantly impaired in 5 and 10-week diabetes. SLX
administration improved relaxation to acetylcholine in 5 and 10-
week diabetes. Diabetes impaired acetylcholine-induced
relaxation of rat aorta irrespective of SLX treatment. Our results
demonstrate that SLX treatment lowers the number of circulating
endothelial cells and improves endothelium-dependent relaxation
in small arteries. These findings suggest endothelium-protective
effect of sulodexide in streptozotocin-induced diabetes.