bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of Oral Health Screening and Referral Guidelines in Primary Health Care
Authors: Zhu Y. , Close K. , Zeldin L.P. , White B.A. , Rozier R.G.
Published: November 2018

Objectives:

To determine the oral health screening and referral practices of pediatric providers, their adherence to American Academy of Pediatrics oral health guidelines, and barriers to adherence.

Methods:

Providers in 10 pediatric practices participating in the North Carolina Quality Improvement Initiative, funded by the Child Health Insurance Program Reauthorization Act of 2009, were asked to complete a 91-item questionnaire. Questions on risk assessment and referral practices were based on those recommended by the American Academy of Pediatrics. Adherence to oral health guidelines was assessed by practitioners’ evaluation of 4 vignettes presenting screening results for an 18-mo-old child with different levels of risk and caries status. Respondents chose referral recommendations assuming adequate and inadequate dentist workforces. Logit models determined the association between barriers specified in Cabana’s framework and adherence (count of 6 to 8 adherent vignettes vs. 0 to 5).

Results:

Of 72 eligible providers, 53 (74%) responded. Almost everyone (98.1%) screened for dental problems; 45.2% referred in at least half of well-child visits. Respondents were aware of oral health guidelines, expressed strong agreement with them, and reported confidence in providing preventive oral health services. Yet they underreferred by an average of 42% per vignette for the 7 clinical vignette-workforce scenarios requiring an immediate referral. Frequently cited barriers were providers’ beliefs that 1) parents are poorly motivated to seek dental care, 2) oral health counseling has a small effect on parent behaviors, 3) there is a shortage of dentists in their community who will see infants and toddlers, and 4) information systems to support referrals are insufficient.

Conclusion:

Pediatric clinicians’ beliefs lead to a conscious decision not to refer many patients, even when children should be referred.

Knowledge Transfer Statement:

Evidence suggests that the primary care–dental referral process needs improvement. This study identifies barriers to delivering recommended preventive oral health services in pediatrics. The information can be used to improve the screening and referral process and, thus, the quality of preventive oral health services provided in primary care. Results also can guide researchers on the selection of interventions that need testing and might close gaps in the referral process and improve access to dental care.
The differentiation between elegance and popularity in the orthography of popular literature of the Ming Dynasty and its causes
Authors: Meilan Zhang , Hao Zhan
Published: November 2018

Through examination of variants in two versions of Jinpingmei, three versions of Water Margin, two versions of Journey to the West, and between relevant sections of Qingpingshantang Scripts, Ancient and Modern Fiction, Jingshi Tongyan, and Amazing Stories, the existence of two trends of elegance and popularity in the orthography of different versions and literary works may be detected. Those texts with a more elegant character have been largely influenced by a strategy of standardized orthography, which is closely related to the creation purpose, knowledge, and cultural awareness of the authors, the willingness of booksellers to produce and sell such works, and their target consumers and readership. The differentiation between elegance and popularity in the character of literary works truly reflects the divergence of different texts within different social strata, which is not only a linguistic and philological question, but also a sociological one.
The Swiss Paediatric Airway Cohort (SPAC)
Authors: Pedersen Eva S.L. , de Jong Carmen C.M. , Ardura-Garcia Cristina , Barben Juerg , Casaulta Carmen , Frey Urs , Jochmann Anja , Latzin Philipp , Moeller Alexander , Regamey Nicolas , Singer Florian , Spycher Ben , Sutter Oliver , Goutaki Myrofora , Kuehni Claudia E.
Published: November 2018

Chronic respiratory symptoms, such as cough, wheeze and dyspnoea, are common in children; however, most research has, with the exception of a few large-scale clinical cohort studies, been performed in the general population or in small, highly-selected samples.

The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians for recurrent conditions, such as wheeze and cough, and exercise-related respiratory problems. The SPAC is an observational study and baseline assessment includes standardised questionnaires for families and data extracted from hospital records, including results of clinically indicated investigations, diagnoses and treatments. Outcomes are assessed through annual questionnaires, monthly symptom reportingviamobile phone and follow-up visits.

The SPAC will address important questions about clinical phenotypes, diagnosis, treatment, and the short- and long-term prognosis of common respiratory problems in children. The cohort currently consists of 347 patients from four major hospitals (Bern, Zurich, Basel and Lucerne), with 70–80 additional patients joining each month. More centres will join and the target sample size is a minimum of 3000 patients.

The SPAC will provide real-life data on children visiting the Swiss healthcare system for common respiratory problems and will provide a research platform for health services research and nested clinical and translational studies.
Urinary tract infection caused by a small colony variant form of capnophilic Escherichia coli leading to misidentification and non-reactions in antimicrobial susceptibility tests
Authors: Park Yu Jin , Le Phuong Nguyen , Pinto Naina Adren , Kwon Mi Jeong , D’Souza Roshan , Byun Jung-Hyun , Sung Heungsup , Yong Dongeun
Published: November 2018

Background

Small colony and capnophilic variant cases have been separately reported, but there has been no reports of their simultaneous presence in one isolate. We report a case of Escherichia coli with coexpressed small colony and capnophilic phenotypes causing misidentification in automated biochemical kits and non-reactions in antimicrobial susceptibility test cards.

Case presentation

An 86-year-old woman developed urinary tract infection from a strain of Escherichia coli with SCV and capnophilic phenotypes in co-existence. This strain did not grow without the presence of CO2, and therefore proper identification from automated system was not possible. 16 s rRNA sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry was able to identify the bacteria.

Conclusion

As these strains do not grow on culture parameters defined by CLSI or on automated systems, proper identification using alternative methods are necessary.
Evaluation of aortic changes in elderly people autopsied with acquired immunodeficiency syndrome
Authors: Oliveira Mariana Silva , Torquato Bianca Gonçalves Silva , da Silveira Luciano Alves Matias , Juliano Gabriela Ribeiro , Aguiar Laura Sanches , Juliano Guilherme Ribeiro , Oliveira Lívia Ferreira , Espindula Ana Paula , Ramalho Luciana Santos , Cavellani Camila Lourencini , da Silva Aline Cristina Souza , de Aquino Favarato Grace Kelly Naves , de Paula Antunes Teixeira Vicente , da Fonseca Ferraz Mara Lúcia
Published: November 2018

Background

To verify the distribution of the degree of fat deposits and percentage of collagen and elastic fibers in the intimal and medial layers of the aorta of elderly patients autopsied, with and without Acquired Immunodeficiency Syndrome (AIDS).

Methods

Twenty-six fragments of the aorta from elderly patients autopsied in the period from 1982 to 2014, were collected and, divided into two groups, being 13 with AIDS and 13 without AIDS. The intensity of the atherosclerosis was macroscopically evaluated in a semi-quantitative way. To quantify the elastic and collagen fibers, it was used the Leica Qwin Plus® software.

Results

In the comparison of the macroscopic intensity of atherosclerosis, the AIDS group (t = 0.6969, p = 0.4992). Regarding elastic fibers, there was a significant increase in the AIDS group (U = 115,800; p < 0.0001). Comparing the groups, there was a significant increase of the collagen fibers in the aortic layers in the AIDS group (U = 114,100; p < 0.0001).

Conclusion

The infection by the HIV influence in the amount of fibers in the extracellular matrix and the intensity of lipid deposit, demonstrating that it may be a risk factor to be considered for the development of atherosclerosis.
Augmentation therapies for treatment-resistant depression: systematic review and meta-analysis
Authors: Strawbridge Rebecca , Carter Ben , Marwood Lindsey , Bandelow Borwin , Tsapekos Dimosthenis , Nikolova Viktoriya L. , Taylor Rachael , Mantingh Tim , de Angel Valeria , Patrick Fiona , Cleare Anthony J. , Young Allan H.
Published: November 2018

Background

Depression is considered to have the highest disability burden of all conditions. Although treatment-resistant depression (TRD) is a key contributor to that burden, there is little understanding of the best treatment approaches for it and specifically the effectiveness of available augmentation approaches.

Aims

We conducted a systematic review and meta-analysis to search and quantify the evidence of psychological and pharmacological augmentation interventions for TRD.

Method

Participants with TRD (defined as insufficient response to at least two antidepressants) were randomised to at least one augmentation treatment in the trial. Pre-post analysis assessed treatment effectiveness, providing an effect size (ES) independent of comparator interventions.

Results

Of 28 trials, 3 investigated psychological treatments and 25 examined pharmacological interventions. Pre-post analyses demonstratedN-methyl-d-aspartate-targeting drugs to have the highest ES (ES = 1.48, 95% CI 1.25–1.71). Other than aripiprazole (four studies, ES = 1.33, 95% CI 1.23–1.44) and lithium (three studies, ES = 1.00, 95% CI 0.81–1.20), treatments were each investigated in less than three studies. Overall, pharmacological (ES = 1.19, 95% CI 1.08–1.30) and psychological (ES = 1.43, 95% CI 0.50–2.36) therapies yielded higher ESs than pill placebo (ES = 0.78, 95% CI 0.66–0.91) and psychological control (ES = 0.94, 95% CI 0.36–1.52).

Conclusions

Despite being used widely in clinical practice, the evidence for augmentation treatments in TRD is sparse. Although pre-post meta-analyses are limited by the absence of direct comparison, this work finds promising evidence across treatment modalities.

Declaration of interest

In the past 3 years, A.H.Y. received honoraria for speaking from AstraZeneca, Lundbeck, Eli Lilly and Sunovion; honoraria for consulting from Allergan, Livanova and Lundbeck, Sunovion and Janssen; and research grant support from Janssen. In the past 3 years, A.J.C. received honoraria for speaking from AstraZeneca and Lundbeck; honoraria for consulting with Allergan, Janssen, Livanova, Lundbeck and Sandoz; support for conference attendance from Janssen; and research grant support from Lundbeck. B.B. has recently been (soon to be) on the speakers/advisory board for Hexal, Lilly, Lundbeck, Mundipharma, Pfizer, and Servier. No other conflicts of interest.
Error in radiology—where are we now?
Authors: Maskell Giles
Published: November 2018

Error is inherent in radiological practice. Our awareness of the extent of this and the reasons behind it has increased in recent times. Our next step must be the development of a shared understanding with our patients of the limitations as well as the huge benefits of medical imaging.
Urinary catheters PART 1
Authors: HIll Barry , Mitchell Michelle
Published: November 2018

Barry HIll, Senior Lecturer in Adult Nursing at Northumbria University ( barry.hill@northumbria.ac.uk ), and Michelle Mitchell, Graduate Tutor for Adult Nursing at Northumbria University, discuss the reasons for urinary catheterisation, the different types of catheter and the potential problems patients need to be aware of
Does listening to music preoperatively reduce anxiety? An evidence-based practice process for novice researchers
Authors: Walker Jacob Christopher , McNaughton Amanda
Published: November 2018

This article discusses the development of a clinical research question, the execution of a systematic literature search strategy, and the critical appraisal of a selected article. It demonstrates an evidence-based review process used by nurses to critique and evaluate the evidence used to support their work. This review was conducted by a novice researcher under the supervision of his lecturer. Learning to conduct an evidence-based practice review enables health professionals to understand how to systematically review primary research relating to clinical practice. This learning experience identified the many facets of a research study that need to be considered to ascertain the validity of the results, and their relevance and application to clinical practice.
The contradictory possibilities of engaging men and boys in the prevention of men’s violence against women in the UK
Authors: Burrell Stephen R
Published: November 2018

Contemporary initiatives to engage men and boys in preventing men’s violence against women in the UK are modest but growing in prominence, and attracting increasing interest from policymakers. This article discusses findings from qualitative research in which expert-informant interviews were carried out with activists playing an influential role in the development of such efforts. It explores how, despite its potential, there are a number of policy obstacles facing work with men in the UK, including ongoing neoliberal austerity, the influence of ‘gender neutral’ conceptions of abuse, and political inertia towards prevention. In addition, the interviews highlighted some of the political contradictions that lie within work which encourages men to question their own power and privilege, and critically evaluate their own practices and those of their peers. These include the need to support rather than supersede the women’s movement, simultaneously appealing to and challenging men, bringing about both individual and structural social change, and building pro-feminist engagements without diluting them. The article argues that, if these contradictions are addressed and pro-feminist equilibriums found within them, then work with men has the potential to make an important contribution as part of efforts to prevent men’s violence against women in the UK.
Impaired Junctions and Invaded Macrophages in Oral Epithelia With Oral Pain
Authors: Yoshimoto Reiko U. , Aijima Reona , Ohyama Yukiko , Yoshizumi Junko , Kitsuki Tomoko , Ohsaki Yasuyoshi , Cao Ai-Lin , Danjo Atsushi , Yamashita Yoshio , Kiyoshima Tamotsu , Kido Mizuho A.
Published: November 2018

Recurrent or chronic oral pain is a great burden for patients. Recently, the links between epithelial barrier loss and disease were extended to include initiation and propagation. To explore the effects of pathohistological changes in oral epithelia on pain, we utilized labial mucosa samples in diagnostic labial gland biopsies from patients with suspected Sjögren’s syndrome (SS), because they frequently experience pain and discomfort. In most labial mucosa samples from patients diagnosed with SS, disseminated epithelial cellular edema was prevalent as ballooning degeneration. The disrupted epithelia contained larger numbers of infiltrating macrophages in patients with oral pain than in patients without pain. Immunohistochemistry revealed that edematous areas were distinct from normal areas, with disarranged cell–cell adhesion molecules (filamentous actin, E-cadherin, β-catenin). Furthermore, edematous areas were devoid of immunostaining for transient receptor potential channel vanilloid 4 (TRPV4), a key molecule in adherens junctions. In an investigation on whether impaired TRPV4 affect cell–cell adhesion, calcium stimulation induced intimate cell–cell contacts among oral epithelial cells from wild-type mice, while intercellular spaces were apparent in cells from TRPV4-knockout mice. The present findings highlight the relationship between macrophages and epithelia in oral pain processing, and identify TRPV4-mediated cell–cell contacts as a possible target for pain treatment.
‘Who’s the girl with the kissin’ lips?’ Constructions of class, popular culture and agentic girlhood in Girl, Princess, Jackie and Bunty in the 1960s
Authors: Gibson Mel
Published: November 2018

This article focuses on four British periodicals incorporating or dominated by comic strips aimed at girls of different ages: Girl (Hulton Press, 1951−64), Princess (Fleetway, 1960−67), Jackie (DC Thomson, 1964−93) and Bunty (DC Thomson, 1958−2001). It will explore how these titles depicted agentic girlhood, class and popular culture. The periodicals show varying degrees of engagement with popular culture, varying according to adult constructions of girls as vulnerable and in need of protection. Some are more permissive and the voice of the girl appears within them, in others there is a more paternalistic approach. This has an impact, in turn, on the kind of content that they offered.
Estudio internacional sobre Relaciones Públicas y Sustentabilidad: el estado del arte en organizaciones brasileñas y ecuatorianas
Authors: Ferrari María-Aparecida , Durán Ana-María
Published: November 2018

El presente texto presenta los resultados de investigación internacional realizada con empresas brasileñas y ecuatorianas con el objetivo de comparar prácticas de relaciones públicas en procesos de sustentabilidad. También se verificó la injerencia  de  las  áreas  de  comunicación  de  las  organizaciones  de  ambos  países  en  los  referidos  procesos.  Los  resultados  arrojados  demuestran  la importancia  del  departamento/área  de  comunicación para impulsar las prácticas de responsabilidad social y sustentabilidad, con el objetivo de aumentar la pertenencia de los empleados en las organizaciones, reforzar la identidad corporativa de las empresas, y facilitar que éstas estrechen lazos con los diferentes stakeholders. El estudio fue estructurado en tres etapas: revisión bibliográfica; investigación cuantitativa con encuestas a 177 responsables de comunicación de ambos países e investigación cualitativa con 18 entrevistas a profesionales seleccionados de la misma muestra. Los resultados indican que falta recorrer para que el proceso de sustentabilidad se afiance en las empresas y que el área de comunicación es esencial para impulsar prácticas de sustentabilidad, aumentar el sentido de pertenencia de los empleados, reforzar la identidad corporativa y estrechar lazos con los diferentes stakeholders.
Paid maternity leave extension and exclusive breastfeeding practice: evidence from Brunei
Authors: Alhaji Mohammed M. , Roslin Sharbawi , Kay Adrian , Tuah Nik A.A.
Published: November 2018

Background

Exclusive breastfeeding (EBF) of infants in their first 6 months postpartum is beneficial. However, maternal employment and short maternity leave impede EBF practice. In 2011, Brunei implemented a new Maternity Leave Regulation to extend paid maternity leave.

Objectives

To compare the prevalence of EBF between employed and nonworking mothers in Brunei, before and after extending paid maternity leave, to determine its effect on EBF and to determine the effects of maternal and infant sociodemographic characteristics.

Methods

Cross-sectional review of feeding records for infants born in 2010 (n = 6412, 85.5% all live births) and 2013 (n = 6680, 85.7%).

Results

EBF prevalence at 6 months postpartum increased from 29% in 2010 to 41% in 2013. EBF prevalence was higher among multiparous mothers (P < 0.001), mothers of Malay ethnicity (P < 0.05), and mothers of girls (P < 0.01 only in 2013) in both years. EBF prevalence among government-employed mothers (81.0%, 67.7%, and 57.8%) was greater than it was among nonworking mothers (79.1%, 66.3%, and 56.9%) by 1.9, 1.4, and 0.9 percentage points, respectively, during the first 3 months of active paid maternity leave in 2013. Mothers employed in the government and private sectors showed greater increases in the practice of EBF (15.5 and 10.8 percentage points respectively) than nonworking mothers (8.8 percentage points) from 2010 to 2013.

Conclusions

EBF prevalence increased after extending paid maternity leave, with the greatest increases seen among employed mothers. Maternal ethnicity, parity, and the sex of the infant were also correlated with EBF.
The future of marine biodiversity and marine ecosystem functioning in UK coastal and territorial waters (including UK Overseas Territories) – with an emphasis on marine macrophyte communities
Authors: Küpper Frithjof C. , Kamenos Nicholas A.
Published: November 2018

Marine biodiversity and ecosystem functioning – including seaweed communities – in the territorial waters of the UK and its Overseas Territories are facing unprecedented pressures. Key stressors are changes in ecosystem functioning due to biodiversity loss caused by ocean warming (species replacement and migration, e.g. affecting kelp forests), sea level rise (e.g. loss of habitats including salt marshes), plastic pollution (e.g. entanglement and ingestion), alien species with increasing numbers of alien seaweeds (e.g. outcompeting native species and parasite transmission), overexploitation (e.g. loss of energy supply further up the food web), habitat destruction (e.g. loss of nursery areas for commercially important species) and ocean acidification (e.g. skeletal weakening of ecosystem engineers including coralline algal beds). These stressors are currently affecting biodiversity, and their impact can be projected for the future. All stressors may act alone or in synergy. Marine biodiversity provides crucial goods and services. Climate change and biodiversity loss pose new challenges for legislation. In particular, there are implications of climate change for the designation and management of Marine Protected Areas and natural carbon storage by marine systems to help control the global climate system. The UK currently has legal obligations to protect biodiversity under international and European law.
Stable Higgs bundles over positive principal elliptic fibrations
Authors: Biswas Indranil , Mj Mahan , Verbitsky Misha
Published: November 2018

Let M be a compact complex manifold of dimension at least three and Π : M → X a positive principal elliptic fibration, where X is a compact Kähler orbifold. Fix a preferred Hermitian metric on M. In [14], the third author proved that every stable vector bundle on M is of the form L⊕ Π ⃰ B0, where B0 is a stable vector bundle on X, and L is a holomorphic line bundle on M. Here we prove that every stable Higgs bundle on M is of the form (L ⊕ Π ⃰B0, Π ⃰ ɸX), where (B0, ɸX) is a stable Higgs bundle on X and L is a holomorphic line bundle on M.
Elevated ESRS, serum FIB, Hcy and stroke history were independent risk factors to PAIS
Authors: Zhang Tao , Li Huiyun , Li Ling , Zhou Faying
Published: November 2018

Background: The aim of this study was to investigate the diagnostic performance of serum homocysteine (Hcy) and Essen stroke risk score (ESRS) in prediction of progressing acute ischemic stroke (PAIS).

Methods One hundred and thirty two acute ischemic stroke (AIS) patients were retrospectively recruited from Daping Hospital, Third Military Medical University from February 2016 to January 2018. The 132 AIS patients were divided into PAIS and non-progressing AIS (NPAIS) groups according to the definition of PAIS. The clinical characteristics, serum Hcy concentration, and ESRS were compared between the PAIS and NPAIS groups. The independent risk factors for PAIS were evaluated by logistic regression analysis. The prediction sensitivity, specificity and area under the ROC curve (AUC) of serum Hcy and ESRS for PAIS were calculated using STATA11.0 software.

Results: The elevated ESRS (OR=1.82, p<0.05), serum fibrinogen (FIB) (OR=1.18, p<0.05), Hcy (OR=1.21, p<0.05) and personal stroke history (OR=1.74, p<0.05) were independent risk factors for PAIS. The serum Hcy of the PAIS and NPAIS groups were 24.59±9.24 (μmol/L) and 18.20±8.29 (μmol/L) respectively with a statistical significance of p<0.05. The ESRS were 3.43±1.09 and 2.60±0.92 for the PAIS and NPAIS groups respectively, with a significance of p<0.05. The prediction sensitivity, specificity and AUC were 76.24%, 67.74% and 0.73 (95%CI:0.63-0.83), respectively, for serum Hcy. For ESRS, the prediction sensitivity, specificity and AUC were 69.99%, 64.52% and 0.74 (95%CI:0.63-0.84) respectively. Correlation between serum Hcy and ESRS was evaluated by a Pearson correlation test. Significant positive correlation between serum Hcy and ESRS was found in PAIS (r=0.54, p<0.05), and NPAIS patients (r=0.78, p<0.01).

Conclusion: Patients with elevated ESRS, serum FIB, Hcy and stroke history had an elevated risk of developing PAIS.
La reescritura del arquetipo de bruja malvada: un análisis comparativo de O mago de Oz y Wicked. Memorias de una bruja mala.
Authors: Casais Vila Verónica
Published: November 2018

Se analiza, desde la perspectiva de la Tematología, la reescritura del arquetipo de la bruja malvada. Con este objetivo, se atiende comparativamente a dos obras clave O mago de Oz, y la posterior reescritura Wicked. Memorias de una bruja mala. Se estudia detalladamente la construcción del personaje de la bruja en cada una de ellas, para acabar por confrontarlas.DOI http://dx.doi.org/10.15304/elos.1.1766
Influence of solution of lactoprotein with sorbitol on ultrastructural changes in lungs of rats in the condition of burn shock
Authors: Ocheretnyuk A. O. , Palamarchuk O. V. , Lysenko D. A. , Vashchuk G. I. , Stepanyuk G. I.
Published: November 2018

This article gives a theoretical substantiation and a new experimental solution of a scientific problem aimed at increasing the effectiveness of pharmacotherapy on the morphofunctional state of the lungs of rats under conditions of burn shock by using a combined colloid-hyperosmolar infusion solution – lacto-protein with sorbitol. The administration of the test solution at a dose of 10 ml/kg for 7 days in rats with modelled burn shock reduced ultrastructural changes in the lungs triggered by burn shock. It has been proved that in the conditions of shock, colloid-hyperosmolar infusion lacto-protein with sorbitol solution facilitates the restoration of vascular endothelium and fluid retention in the microcirculatory channel and improves the morphofunctional state of the aerohematic barrier of the lungs, stimulates the activity of the alveolar macrophages and the secretory function of the type II alveolocytes producing surfactant. At day 7 of burn shock, when 0.9% of NaCl was injected, significant changes were observed in the respiratory unit: part of the alveoli had considerably enhanced clearance of blood capillaries, which had platelets, neutrophils and altered forms of erythrocytes. At day 7 of burn shock in the lungs of the rats given an infusion of colloid-hyperosmolar solution – lactoprotein with sorbitol, the ultrastructure of the components of the lung cells had improved in comparison with 3 days. Luminosity of the hemocapillary parts was moderate, mainly with erythrocytes. The walls of endothelial cells had elongated nuclei with invaginations of nuclear membranes and clear contours. Their cytoplasmic regions were not widespread, with moderate electron densities. In type II alveolocytes, during this experiment, a lower degree of damage to the nucleus and organelles in the cytoplasm was established, and there were signs of a renewal of the secretory function of these cells. In the cytoplasm, hypertrophied mitochondria with clear crystals, different sizes of secretory granules, which had a different density, indicating their formation, were observed. According to the magnitude of the cytoprotective effect on lung cells under conditions of burn shock, the lactoprotein with sorbitol solution was shown to be superior in comparison with the physical solution (0.9% NaCl). The study of functional, biochemical and molecular genetic parameters that characterize the state of the aerohematic barrier under the conditions of using lactoprotein with sorbitol solution in the case of burn injuries of the skin will allow researchers to comprehensively evaluate the mechanisms of the pulmonary protective effect of this preparation and to experimentally substantiate the expediency of its use in clinical practice for pharmaco-correction of burn shock.
Heterostereotype of Ukraine in the discourse of quality British newspapers
Authors: Butyrina M. , Garkavenko Y.
Published: November 2018

The study is dedicated to the issues of media reception of Ukraine by British quality newspapers, that largely determines the nature of intergovernmental cooperation and the geopolitical priorities of the European community in the Ukrainian issue as a whole. This issue can be solved by pointing out the most frequent heterostereotypes, identifying their formal content features and operating contexts in the text space of the media.The new concept that is called the «Stereotype of the Transition Period» has been updated, which, on one hand, indicates the specifics of the object of stereotyping, and on the other hand, motivates the receptive features of the subjects of stereotyping, which are the British articles in our study. The investigation of heterostereotyping of Ukraine was carried out by using the programmatic content analysis AntConc 3.5.0 (Windows), which can be characterized by the signs of validity, objectivity and reliability. The most frequent heterostereotypes formed by the process of combining of the ethnonym "Ukraine" with occasionally relevant concepts are revealed, and their semantic fields are analyzed.It is stated that conflict-related issues are mostly chosen by British quality newspapers to cover the Ukrainian theme. It becomes a discursive background for representing Ukrainian society as polarized, split according to geographical, cultural, linguistic and ideological parameters. Ukraine is presented as a state with the divided identity. Among the heterosterotypical images, the militarized image of our state dominates. Among the frequent contexts of ethnonym, the contexts of war, political crisis and environmental catastrophe are outlined.It is revealed that in the materials on Ukrainian subjects, the concept «Russia» dominates over the concept of "Ukraine". It is pointed out that the British media legitimize certain institutions and phenomena that are tabooed in the Ukrainian media-discourse practices.The results obtained have a theoretical significance for «Social Communications» field and can be used in technological developments to create and correct the image of Ukraine.
Percepciones y experiencias de usuarias sobre las limitaciones sanitarias para la promoción de lactancia materna
Authors: Rangel-Flores Yesica Yolanda , Martínez Plascencia Ulises , Rodriguez Martínez Ma. Estela
Published: November 2018

Objetivo Comprender las percepciones y experiencias que usuarias de distintos servicios de salud han desarrollado respecto a las limitaciones sanitarias para la promoción de la Lactancia Materna.Metodología Investigación cualitativa con enfoque fenomenológico. Se aplicaron entrevistas en profundidad a 12 madres que habitan en una comunidad clasificada con alto nivel de marginación en San Luis Potosí, México, cuyos partos fueron atendidos en servicios de salud públicos, privados y de seguridad social. Se realizó análisis fenomenológico sobre las entrevistas trascritas en totalidad.Resultados Con independencia del tipo de atención sanitaria, las mujeres reciben poca capacitación para la lactancia durante la etapa prenatal y la mayor parte de esta ocurre de manera impersonal. La mayoría narra experiencias de exigencia y juzgamiento, más que de consejería, por parte del personal de salud.Conclusión La lactancia materna es contemplada como derivada de una decisión personal e individual, en la que no impacta la consejería del personal sanitario. Es necesario impulsar procesos de capacitación y sensibilización dirigidos a fortalecer las habilidades de acompañamiento para la Lactancia Materna en el personal de salud, con el fin de ejercer la función de consejería de manera asertiva.
The Role of Redox Proteins in Arresting Proliferation of Breast Epithelial Cells Under Oxidative Stress
Authors: Shakhristova Evgeniya V. , Stepovaya Elena A. , Rudikov Evgeniy V. , Sushitskaya Olga S. , Rodionova Daria O. , Novitsky Vaycheslav V.
Published: November 2018

Background: Redox status imbalance against the backdrop of oxidative stress development underlies the pathogenesis of a whole range of diseases. Many intracellular proteins contain free thiol groups and undergo redox regulation which is one of the key processes in controlling cell proliferation. Thioredoxin and glutaredoxin are involved in maintaining intracellular redox homeostasis and act as candidates in regulating proliferation. This provides prospects for future development of methods for diagnosis and targeted therapy of socially sensitive diseases accompanied by oxidative stress. The aim of the study is to reveal the role of redox proteins in molecular mechanisms of regulating HBL-100 breast epithelial cell proliferation under the effect of roscovitine, a cell cycle inhibitor. Materials and methods: Two research groups were formed. They included HBL-100 human breast epithelial cells incubated in the presence and absence of 20 mcM roscovitine for 18 hours. The intracellular thioredoxin levels were determined using Western blot analysis with specific monoclonal antibodies. Distribution of the cells among cell cycle phases were evaluated by flow cytometry. The activity of glutathione reductase, glutathione peroxidase, and thioredoxin reductase were measured by spectrophotometry. Results: Under the effect of roscovitine in the HBL-100 cells, cell cycle arrest in the G2/М phases occurred and oxidative stress developed. In the meantime, the decrease in the thioredoxin and glutaredoxin concentrations was registered along with the change in the functional activity of glutathione-dependent enzymes. Conclusions: Application of roscovitine, a cell cycle inhibitor, allowed creating a model of oxidative stress in the breast epithelial cells against the backdrop of inhibited cell proliferation. We identified that thioredoxin and glutaredoxin contributed to impairment of cell cycle progression. It points at a possibility to regulate cell proliferation by modulating the functional features of cellular redox-dependent proteins in different pathologies accompanied by oxidative stress.
UV-radiation as a Risk Factor for Non-melanoma Skin Cancer. Genetic Determinants of Carcinogenesis
Authors: Zhilova Marianna B. , Butareva Maria M.
Published: November 2018

The review presents modern data on the role of ultraviolet (UV) radiation in the pathogenesis of non-melanoma skin cancer (NMSC), the problem of THE risk of developing NMSC, in particular, squamous cell and basal cell skin cancer both in the population and in long-term repeated irradiation of phototherapy (PUVA therapy, UVB therapy, UVB-311 therapy) in patients with psoriasis. The paper considers the mechanisms of UV-induced cell damage by different spectral ranges (UVA, UVB) including the formation of photoproducts, damage to genomic DNA and other cellular structures, violation of the regulation of signaling pathways, the development of chronic inflammation, secondary immunosuppression. The review summarizes the results of large epidemiological studies discussing the role of gene polymorphisms in the homologous DNA repair XRCC3, gene telomerase TERT-CLPTMI, cytokine IL10 gene, MTHFR gene, encoding the folate synthesis, genes involved in pigmentirovanie MC1R, EXOC2, UBAC2 in the modulation of risk of carcinogenic effect of UV radiation. According to the authors’ opinion, the most vital and significant is data on the role of vitamin D receptor (VDR) gene polymorphisms as possible predictors of the risk of NMSC development. The further prospects of academic research on the cumulative role of the genome and environmental factors in the risk assessment of NMSC are revealed.
Questionnaire Eye Movements Complaints v1
Authors: Nij Bijvank Jenny
Published: November 2018

Questionnaire on eye movements complaints Can be used for descriptive purposes only
Проблемы национального развития и консолидации политических пространств (на примере Молдовы и Румынии)
Authors: Бардин Андрей , Баринов Игорь
Published: November 2018

В статье на основании анализа глубинных интервью с экспертами из Молдовы и Румынии исследуются наиболее значимые социально-экономические, политико-институциональные и социокультурные факторы, равнодействующей которых стало фактическое оформление данных страновых пространств как “территорий неразвития” и которые могут сыграть определяющую роль в будущем сохранении либо изменении этого статуса. Рассмотрены исторические особенности нациестроительства и политики идентичности в Румынии и Молдове и их актуальные контексты, паттерны идентичности и самореализации граждан, характер общественных размежеваний, состояние коммуникативного поля общества и власти, взаимодействие с наднациональными образованиями. По мнению авторов, ключевыми факторами, способствующими консервации территорий неразвития, выступают постоянно растущий разрыв между обществом и властью на фоне системной коррупции последней, отсутствие последовательной политики формирования и консолидации гражданской нации и в целом – выстраивания и совместной с обществом реализации самобытного политического национального проекта. Помимо этих факторов значительную роль в исследуемых случаях играет также неэффективное использование внутреннего потенциала развития вкупе с сохранением комплекса нерешенных социально-экономических проблем.
Risk factors, microbiological findings and outcomes of necrotizing fasciitis at a tertiary care centre
Authors: S. R. Divakara , P. B. Thrishuli , Teli Bhavuray
Published: November 2018

Background: Necrotizing fasciitis (NF) is a uncommon and serious infection involving the skin and subcutaneous tissues of lower and upper limbs, perineal area (Fournier’s gangrene), and the abdominal wall with high morbidity and mortality. Early diagnosis and aggressive treatment can reduce the mortality rate of NF. The objectives of this study are to study the etiolopathological, microbiological factors determining the outcome of necrotizing fasciitis.Methods: It is prospective study and was conducted in JSS Medical College and Hospital in October 2008 to October 2010. Total 50 patients diagnosed with necrotizing fasciitis were admitted to JSS Medical College and Hospital. Demographic data, type of co morbidities, site of infection, clinical features with microbiology and laboratory results, and outcomes of patients were analyzed.Results: Out of 50 patients there were 42 males and 8 females. Highest number of cases was found in the age group of 65-74 years among males, 55-64 years among females. The commonest site in the present study is lower limbs (74%). Diabetes mellitus was the commonest (76%) co morbidity. Beta hemolytic streptococci 22 (44%) was the highest to be isolated. In type I and Coagulase positive staphylococci 18 (36%) was the commonest organism isolated in type II necrotizing fasciitis. The significant risk factors were gender, comorbidties, hospital length of stay, and albumin level, leucocytosis, anemia, hypoalbumenia, low serum ferritin levels increase blood sugar levels. The mortality was 12% (8 patients).Conclusions: Patients with advance age, co-morbid conditions like diabetes mellitus, hypertension, peripheral vascular disease, osteomyelitis had high unexplained susceptibility to the disease and with a higher incidence in males. Thus, early recognition with a high index of clinical suspicion would definitely reduce both morbidity and mortality. It has gross morbidity and mortality if not treated in its early stages. Leucocytosis, anemia, hypoalbumenia, low serum ferritin levels, increase blood sugar levels were consistent findings seen in majority of the patients which resulted in increased morbidity.
10 anos de produção científica sobre Contabilidade Pública no Brasil
Authors: Fabre Valkyrie Vieira , Bonfante Ernani Augusto
Published: November 2018

This study aims to verify the characteristics of the scientific production of papers in the area of Public or Government Accounting. It is a qualitative, descriptive, bibliographical survey that was used in bibliometrics to present the results. The data is from the papers published on Capes’ Periódicos website in the last 10 years (2007-2016), and a sample of 113 papers was stratified. The theoretical framework presents current papers, related to research in the area of public accounting, making evident the low production and great dispersion among the authors. Several authors report the growth of scientific interest in this area and show the need for bibliometric studies in this area. Based on a mix between the Laws of Bradford, Lotka and Zipf this bibliometric study shows that the periodicals with the greatest publication in the area are: Revista de Administração Pública (RAP), Revista de Gestão da USP, Revista Contabilidade & Finanças; and the Journal of Management, Finance and Accounting. The production is dispersed and the most prolific authors did not have more than 3 papers published in the period, although most of the productions have triple authorship. As for the methodology, most of the researches are qualitative, descriptive and are used as a documentary survey. The thematic was grouped in 16 foci, identified and compared to the intensity of annual production. This research corroborates previous studies, which claim that public accounting is a rapidly expanding area and requires bibliometric studies to guide research within the vast area of practice and considerable dispersion among authors in the area.
Tração Do Bem: Construindo Conhecimentos Através Do Assistencialismo Veterinário
Authors: Pedrosa Paloma Nascimento , Duarte Amélia Lizziane Leite , Ferreira Talles Luann Abrantes , Queiroga Camila Márcia De Andrade , Do Nascimento Amaíra Casimiro , Da Silva Welitânia Inácia
Published: November 2018

Equines are fundamental for the development of the work of cartwrights because they help themto obtain their family income .This article aims to contribute with the expansion of knowledge about the proper management and working conditions of the animals and focuses on the health and welfare of the horses that belong to the cartwrights in the city of Sousa - PB. Visits took place in peripheral neighborhoods and open fairs. During the visits we identified 36 out of 40 animals. Throughout the project there were interventions such as application of questionnaires to the owners, educational actions, general and specific clinical care and lectures with explanations about diseases and adequate animal management. The project also covered the families of the workers, the population of the peripheral neighborhoods and their social circles..Traction equines treated by the project received veterinary medical treatment such as clinical examination and worming and wound treatment. We had some lectures on the topic and the students participating in the project acted the play “The dumb buddy”.. Results indicate that several animals have diseases and receive inadequate management, some do not receive water or food during the day, affecting their performance and quality of life due to lack of information
Motivação voluntária na Casa da Criança com Câncer no município de João Pessoa-PB
Authors: Constantino Maria Do Desterro Sabino , Pereira Helio Araújo
Published: November 2018

This paper aims to identify the voluntary motivations that lead people to volunteer at the House of the Child with Cancer. The empirical part of the article had as a locus the House of the Child with Cancer located in the municipality of João Pessoa/PB. The empirical data was collected based on the theoretical model of Cavalcante (2012), which identifies the motivations within voluntary work. Through this research it is possible to manage people in the third sector. The quantitative method of research was applied, including the use of 30 questionnaires with all volunteers working in the House of the Child with Cancer. Statistical measures were used for data analysis, standard deviation and coefficient of variation. The results showed that, in the following order, the major motivational variables of the research participants in the institution are related to: selflessness, learning and social justice. It is also observed that the selfish motivational variable was the least relevant for the volunteers in terms of voluntary motivation.
ESTRUTURA E DINÂMICA DE UMA ÁREA MANEJADA NA FLORESTA NACIONAL DO TAPAJÓS
Authors: Bezerra Talita Godinho , De Sousa Lima Antônio Ozenilto , Rocha de Araújo Jéssica Thaíse , Dos Santos Milla Graziely Silveira , Prado Neves Raphael Lobato , Moraes Giselli Castilho , Melo Lia De Oliveira
Published: November 2018

Objetivou-se, neste estudo, avaliar a estrutura e a dinâmica de uma comunidade arbórea, antes e após a intervenção florestal, na Floresta Nacional do Tapajós. Para isso, instalou-se, aleatoriamente, 10 parcelas permanentes de 50 x 50 m em uma Unidade de Produção Anual (1.000 ha) e realizou-se medições antes e após a intervenção, nos anos de 2012 e 2015, respectivamente. A análise revelou que a extração de madeira provocou alteração no número de indivíduos, área basal e volume, porém não afetou a distribuição diamétrica dos indivíduos arbóreos. O crescimento médio anual em diâmetro, considerando todas as árvores com DAP ? 10 cm, ficou em torno de 0,34 cm.ano-1. As árvores com copas totalmente expostas à luz, ausentes de cipó e sem danos, cresceram mais que as sombreadas, com cipós e danos restringindo seu crescimento. A mortalidade foi superior aos ingressos de novas árvores, refletindo um balanço negativo comum em áreas recém exploradas. Após a intervenção, a floresta estudada conseguiu manter suas características semelhantes à floresta original.PALAVRAS-CHAVE: Crescimento de florestas, Manejo florestal, Parcelas permanentes.
QUALIDADE DA ESTRUTURA DO SOLO EM SISTEMA INTEGRADO DE PRODUÇÃO AGROPECUÁRIA NO MUNICÍPIO DE ARIQUEMES, RONDÔNIA
Authors: Cipriani Lucas Pedro , Ávila Julyana Corrêa de , Souza Rogério Carlos de , Rodrigues Edneia Maria Sobrinho , Soares Edimar Rodrigues , Nogueira Adriana Ema
Published: November 2018

Objetivou-se avaliar a qualidade da estrutura do solo, em um sistema integrado de produção agropecuária. O estudo foi realizado na fazenda Esperança, no município de Ariquemes-RO, em agosto de 2017. Foram amostradas três áreas pertencentes ao sistema integrado de produção e uma área de pastagem extensiva. A área 1 apresenta antecedentes de cultivo em sucessão de milho/ Brachiaria ruziziensis (sem pastejo) no ano agrícola 2015/2016 e uma safra de soja em 2016/2017. Na área 2 anteriormente ocorreu o cultivo em sucessão de soja/milho/Brachiaria ruziziensis (com pastejo) no ano agrícola 2014/2015 com 1 safra de soja em 2015/2016 e novamente soja em 2016/2017. A área 3 é proveniente de sucessão Brachiaria ruziziensis/soja (sem pastejo) no ano agrícola de 2014/2015, seguida de 1 safra de soja em 2015/2016 e novamente soja/Brachiaria ruziziensis em 2016/2017. A área 4, era constituída de uma pastagem degradada. Avaliou-se a qualidade da estrutura do solo visualmente, pelo método de diagnóstico rápido da estrutura do solo, atribuindo notas de 1 a 6 para o Índice de qualidade estrutural do solo (IQES). Os manejos empregados nas áreas 1, 2 e 3 proporcionaram a obtenção de qualidade estrutural do solo superior a da área 4 (área de pastagem degradada), sendo observadas as seguintes notas 4,87; 4,67; 5,67 e 2,57, para as áreas 1, 2, 3 e 4, respectivamente. A Sucessão Brachiaria ruziziensis/soja (sem pastejo), soja, soja/Brachiaria ruziziensis resultou em melhor qualidade da estrutura do solo. A pastagem degradada apresentou qualidade da estrutura do solo ruim. PALAVRAS-CHAVE: Estrutura do solo, Manejo do solo, Plantio direto.