bluuebunny/crossref_metadata_2025 huggingface dataset:
The work of collecting: Objects, sociality and self in Leïla Sebbar’s Lettres parisiennes and Mes Algéries en France
Authors: Wilson Sonia
Published: October 2016

This article investigates the ways in which Leïla Sebbar draws on collecting practices as a means of performing what Marianne Hirsch has called postmemorial work. It begins with a close analysis of Sebbar’s accounts of the small, apparently trivial objects with which she surrounds herself, and how these accounts function as part of the narrative identity work in which she engages in the course of Lettres parisiennes. The insight afforded Sebbar into her own collecting practices in the course of this correspondence, and in particular her understanding of personal collecting as a social act, can be seen as subtending the composition of Mes Algéries en France, published 18 years later. Sebbar has now shifted from asking herself why particular objects have accumulated about her to displaying the work that collection performs. By juxtaposing and interspersing photographs of her own collections with those of others and with objects clearly designated as constituent parts of other collections, Sebbar crafts an archival site that negotiates between personal, familial and institutional contexts of display to designate the history of France–Algeria as constructed by the particular kinds of encounters that occur between people and objects in each.
Incidental renal tumours on low-dose CT lung cancer screening exams
Authors: Pinsky Paul F , Dunn Barbara , Gierada David , Nath P Hrudaya , Munden Reginald , Berland Lincoln , Kramer Barnett S
Published: October 2016

Introduction

Renal cancer incidence has increased markedly in the United States in recent decades, largely due to incidentally detected tumours from computed tomography imaging. Here, we analyze the potential for low-dose computed tomography lung cancer screening to detect renal cancer.

Methods

The National Lung Screening Trial randomized subjects to three annual screens with either low-dose computed tomography or chest X-ray. Eligibility criteria included 30 + pack-years, current smoking or quit within 15 years, and age 55–74. Subjects were followed for seven years. Low-dose computed tomography screening forms collected information on lung cancer and non-lung cancer abnormalities, including abnormalities below the diaphragm. A reader study was performed on a sample of National Lung Screening Trial low-dose computed tomography images assessing presence of abnormalities below the diaphragms and abnormalities suspicious for renal cancer.

Results

There were 26,722 and 26,732 subjects enrolled in the low-dose computed tomography and chest X-ray arms, respectively, and there were 104 and 85 renal cancer cases diagnosed, respectively (relative risk = 1.22, 95% CI: 0.9–1.5). From 75,126 low-dose computed tomography screens, there were 46 renal cancer diagnoses within one year. Abnormalities below the diaphragm rates were 39.1% in screens with renal cancer versus 4.1% in screens without (P < 0.001). Cases with abnormalities below the diaphragms had shorter median time to diagnosis than those without (71 vs. 160 days, P = 0.004). In the reader study, 64% of renal cancer cases versus 13% of non-cases had abnormalities below the diaphragms; 55% of cases and 0.8% of non-cases had a finding suspicious for renal cancer (P < 0.001).

Conclusion

Low-dose computed tomography screens can potentially detect renal cancers. The benefits to harms tradeoff of incidental detection of renal tumours on low-dose computed tomography is unknown.
Combining intention and emotional state inference in a dynamic neural field architecture for human-robot joint action
Authors: Silva Rui , Louro Luís , Malheiro Tiago , Erlhagen Wolfram , Bicho Estela
Published: October 2016

We report on our approach towards creating socially intelligent robots, which is heavily inspired by recent experimental findings about the neurocognitive mechanisms underlying action and emotion understanding in humans. Our approach uses neuro-dynamics as a theoretical language to model cognition, emotional states, decision making and action. The control architecture is formalized by a coupled system of dynamic neural fields representing a distributed network of local but connected neural populations. Different pools of neurons encode relevant information in the form of self-sustained activation patterns, which are triggered by input from connected populations and evolve continuously in time. The architecture implements a dynamic and flexible context-dependent mapping from observed hand and facial actions of the human onto adequate complementary behaviors of the robot that take into account the inferred goal and inferred emotional state of the co-actor. The dynamic control architecture was validated in multiple scenarios in which an anthropomorphic robot and a human operator assemble a toy object from its components. The scenarios focus on the robot’s capacity to understand the human’s actions, and emotional states, detect errors and adapt its behavior accordingly by adjusting its decisions and movements during the execution of the task.
Outline of a sensory-motor perspective on intrinsically moral agents
Authors: Balkenius Christian , Cañamero Lola , Pärnamets Philip , Johansson Birger , Butz Martin V , Olsson Andreas
Published: October 2016

We propose that moral behaviour of artificial agents could (and should) be intrinsically grounded in their own sensory-motor experiences. Such an ability depends critically on seven types of competencies. First, intrinsic morality should be grounded in the internal values of the robot arising from its physiology and embodiment. Second, the moral principles of robots should develop through their interactions with the environment and with other agents. Third, we claim that the dynamics of moral (or social) emotions closely follows that of other non-social emotions used in valuation and decision making. Fourth, we explain how moral emotions can be learned from the observation of others. Fifth, we argue that to assess social interaction, a robot should be able to learn about and understand responsibility and causation. Sixth, we explain how mechanisms that can learn the consequences of actions are necessary for a robot to make moral decisions. Seventh, we describe how the moral evaluation mechanisms outlined can be extended to situations where a robot should understand the goals of others. Finally, we argue that these competencies lay the foundation for robots that can feel guilt, shame and pride, that have compassion and that know how to assign responsibility and blame.
Emotional affordances for human–robot interaction
Authors: Vallverdú Jordi , Trovato Gabriele
Published: October 2016

This paper provides a new concept for the improvement of human–robot interaction (HRI) models: ‘emotional affordances’. Emotional affordances are all the mechanisms that have emotional content as a way to transmit and/or collect emotional meaning about any context; it can include bodily expressions, social norms, values-laden objects or extended space, among others. With this rich concept, we open the way to new ways to understand the multimodal and complex nature of emotional mechanisms. Based on the grounded emotional mechanisms of human cognition and behaviour (that is, based and result of the bodily structure and its coupled relationship with the natural and/or social environment), the purpose of this paper is focused on the definition of a framework for the design of a taxonomy of emotional affordances, useful for a modal and improved understanding of the domains of emotional interactions that can emerge between humans and robots. This process will make possible in next research steps to define processing modules as well as to elicit visual display outputs (expressing emotions). Consequently, with this project we provide robotic experts with a unified taxonomy of human emotional affordances, useful for the improvement of HRI projects.
Acute Achilles Tendon Rupture Treated by Double Side-Locking Loop Suture Technique With Early Rehabilitation
Authors: Miyamoto Wataru , Imade Shinji , Innami Ken , Kawano Hirotaka , Takao Masato
Published: October 2016

Background:

Although early accelerated rehabilitation is recommended for the treatment of acute Achilles tendon rupture, most traditional rehabilitation techniques require some type of brace.

Methods:

We retrospectively analyzed 44 feet of 44 patients (25 male and 19 female) with a mean age of 31.8 years who had an acute Achilles tendon rupture related to athletic activity. Patients had been treated by a double side-locking loop suture (SLLS) technique using double antislip knots between stumps and had undergone early accelerated rehabilitation, including active and passive range of motion exercises on the day following the operation and full weight-bearing at 4 weeks. No brace was applied postoperatively. The evaluation criteria included the American Orthopaedic Foot & Ankle Society Ankle-Hindfoot Scale (AOFAS) score; active plantar flexion and dorsiflexion angles; and the intervals between surgery and the time when patients could walk normally without any support, perform double-leg heel raises, and perform 20 continuous single-leg heel raises of the operated foot.

Results:

Despite postoperative early accelerated rehabilitation, the AOFAS score and active dorsiflexion angles improved over time (6, 12, and 24 weeks and 2 years). A mean of 4.3 ± 0.6 weeks was required for patients to be able to walk normally without any support. The mean period to perform double-leg heel raises and 20 continuous single-leg heel raises of the injured foot was 8.0 ± 1.3 weeks and 10.9 ± 2.1 weeks, respectively. All patients, except one who was engaged in classical ballet, could return to their preinjury level of athletic activities, and the interval between operation and return to athletic activities was 17.1 ± 3.7 weeks.

Conclusion:

The double SLLS technique with double antislip knots between stumps adjusted the tension of the sutured Achilles tendon at the ideal ankle position and provided good clinical outcomes following accelerated rehabilitation after surgery without the use of a brace.

Level of Evidence:

Level IV, retrospective case series.
Neuroanatomical Substrates for Risk Behavior
Authors: Levy Ifat
Published: October 2016

Individuals vary substantially in their tendency to take risks. In the past two decades, a large number of neuroimaging studies in humans have explored the neural mechanisms of several cognitive processes that contribute to risk taking. In this article, I focus on functional and structural MRI studies that investigated uncertainty processing, one of the main features of risk behavior. Using decision-making and learning paradigms, these studies implicated a network of brain areas, including posterior parietal cortex, anterior insula, anterior cingulate cortex, and ventrolateral prefrontal cortex, in various aspects of uncertainty processing. Individual differences in behavior under uncertainty are reflected in the function and structure of some of these areas and are integrated into value representations in ventromedial prefrontal cortex and ventral striatum, reinforcing the potential contribution of all of these brain structures to individual tendencies to take risks.
A graduated food addiction classification approach significantly differentiates obesity among people with type 2 diabetes
Authors: Raymond Karren-Lee , Kannis-Dymand Lee , Lovell Geoff P
Published: October 2016

This study examined a graduated severity level approach to food addiction classification against associations with World Health Organization obesity classifications (body mass index, kg/m2) among 408 people with type 2 diabetes. A survey including the Yale Food Addiction Scale and several demographic questions demonstrated four distinct Yale Food Addiction Scale symptom severity groups (in line with Diagnostic and Statistical Manual of Mental Disorders (5th ed.) severity indicators): non-food addiction, mild food addiction, moderate food addiction and severe food addiction. Analysis of variance with post hoc tests demonstrated each severity classification group was significantly different in body mass index, with each grouping being associated with increased World Health Organization obesity classifications. These findings have implications for diagnosing food addiction and implementing treatment and prevention methodologies of obesity among people with type 2 diabetes.
Modeling information flow for an autonomous agent to support reverse engineering work
Authors: Sisco Zachary D , Dudenhofer Patrick P , Bryant Adam R
Published: October 2016

Reverse engineering is a cyber defense task used to investigate malware, reconstruct functionality of compiled software, and identify vulnerabilities from closed-source software code already being used in operational contexts. While research in this area has mainly focused on techniques to extract information from binary code, it is also important to understand the capabilities and limitations of the human involved in the reverse engineering process (both defensively and offensively), so we can design better information representations and effectively allocate appropriate tasks to autonomous agents. In this paper, we describe our introductory work in developing agent models of reverse engineering. We review what is known about reverse engineers’ mental models, then describe and characterize four human–computer interaction patterns involved in reverse engineering from a cognitive task analysis. Finally, we present a category theoretic model to describe how reverse engineers trace information flow when performing static analysis. Our approach is a first step in modeling, simulating, and optimizing the human interaction components of these tasks to increase the speed, scale, and accuracy of cyber defense efforts.
Hepatic capsular rupture in pregnancy
Authors: Frise Charlotte J , Davis Peyton , Barker Graham , Wilkinson Douglas , Mackillop Lucy
Published: October 2016

The syndrome of haemolysis, elevated liver enzymes and low platelets is a rare condition specific to pregnancy, affecting approximately 5–20% of all pre-eclamptic pregnancies. Described here is a woman in her first pregnancy, who experienced an intrauterine death following a significant hepatic haematoma and capsular rupture, in the absence of classical clinical features suggestive of pre-eclampsia. The events that followed suggested haemolysis, elevated liver enzymes and low platelets syndrome as the likely diagnosis. The patient’s clinical course highlights the difficulties that may be encountered when making decisions about pregnant women with complicated medical and obstetric issues.
Pregnancy and lactation during long-term total parenteral nutrition: A case report and literature review
Authors: Borbolla Foster Ailsa , Dixon Steven , Tyrrell-Price J , Trinder Johanna
Published: October 2016

There is a paucity of clinical data regarding the management of pregnancy and lactation in women requiring long-term total parenteral nutrition with complex nutritional needs. This case report and literature review highlights common challenges in care and presents evidence which can guide the obstetrician’s approach to care.
Evolution of Chagas’ disease in Brazil. Epidemiological perspective and challenges for the future: a critical review
Authors: Bello Corassa Rafael , Aceijas Carmen , Alves Paula Aryane Brito , Garelick Hemda
Published: October 2016

Aims:

This article aimed to provide a critical review of the evolution of Chagas’ disease (ChD) in Brazil, its magnitude, historical development and management, and challenges for the future.

Methods:

A literature search was performed using PubMed, SciELO and Google Scholar and throughout collected articles’ references. Narrative analysis was structured around five main themes identified: vector transmission, control programme, transfusion, oral and congenital transmission.

Results:

In Brazil, the Chagas’ Disease Control Programme was fully implemented in the 1980s, when it reached practically all the endemic areas, and in 1991, the Southern Cone Initiative was created, aiming to control the disease transmission through eliminating the Triatoma infestans and controlling blood banks. As a result, the prevalence of chagasic donors in blood banks reduced from 4.4% in the 1980s to 0.2% in 2005. In 2006, Pan American Health Organization (PAHO) certified the interruption of transmission of ChD through this vector in Brazil. However, there are still challenges, such as the domiciliation of new vector species, the need for medical care of the infected individuals, the prevention of alternative mechanisms of transmission, the loss of political concern regarding the disease and the weakening of the control programme.

Conclusion:

Despite the progress towards control, there are still many challenges ahead to maintain and expand such control and minimise the risk of re-emergence.
Creating connections – the development of a mobile-health monitoring system for heart failure: Qualitative findings from a usability cohort study
Authors: Chantler Tracey , Paton Chris , Velardo Carmelo , Triantafyllidis Andreas , Shah Syed A , Stoppani Emma , Conrad Nathalie , Fitzpatrick Ray , Tarassenko Lionel , Rahimi Kazem
Published: October 2016

Objective

There is significant interest in the role of digital health technology in enabling optimal monitoring of heart failure patients. To harness this potential, it is vital to account for users’ capacity and preferences in the development of technological solutions. We adopted an iterative approach focussed on learning from users’ interactions with a mobile-health monitoring system.

Methods

We used a participatory mixed methods research approach to develop and evaluate a mobile-health monitoring system. Fifty-eight heart failure patients were recruited from three health care settings in the UK and provided with Internet-enabled tablet computers that were wirelessly linked to sensor devices for blood pressure, heart rate and weight monitoring. One to two home visits were conducted with a subgroup of 29 participants to evaluate the usability of the system over a median follow-up period of six months. The thematic analysis of observational data and 45 interviews was informed by the domestication of technology theory.

Results

Our findings indicate that digital health technologies need to create and extend connections with health professionals, be incorporated into users’ daily routines, and be personalised according to users’ technological competencies and interest in assuming a proactive or more passive role in monitoring their condition.

Conclusions

Users' patterns of engagement with health technology changes over time and varies according to their need and capacity to use the technology. Incorporating diverse user experiences in the development and maintenance of mobile-health systems is likely to increase the extent of successful uptake and impacts on outcomes for patients and providers.
Cost-Effectiveness of Skin Surveillance Through a Specialized Clinic for Patients at High Risk of Melanoma
Authors: Watts Caroline G. , Cust Anne E. , Menzies Scott W. , Mann Graham J. , Morton Rachael L.
Published: October 2016

Purpose

Clinical guidelines recommend that people at high risk of melanoma receive regular surveillance to improve survival through early detection. A specialized High Risk Clinic in Sydney, Australia was found to be effective for this purpose; however, wider implementation of this clinical service requires evidence of cost-effectiveness and data addressing potential overtreatment of suspicious skin lesions.

Patients and Methods

A decision-analytic model was built to compare the costs and benefits of specialized surveillance compared with standard care over a 10-year period, from a health system perspective. A high-risk standard care cohort was obtained using linked population data, comprising the Sax Institute’s 45 and Up cohort study, linked to Medicare Benefits Schedule claims data, the cancer registry, and hospital admissions data. Benefits were measured in quality-adjusted life-years gained. Sensitivity analyses were undertaken for all model parameters.

Results

Specialized surveillance through the High Risk Clinic was both less expensive and more effective than standard care. The mean saving was A$6,828 (95% CI, $5,564 to $8,092) per patient, and the mean quality-adjusted life-year gain was 0.31 (95% CI, 0.27 to 0.35). The main drivers of the differences were detection of melanoma at an earlier stage resulting in less extensive treatment and a lower annual mean excision rate for suspicious lesions in specialized surveillance (0.81; 95% CI, 0.72 to 0.91) compared with standard care (2.55; 95% CI, 2.34 to 2.76). The results were robust when tested in sensitivity analyses.

Conclusion

Specialized surveillance was a cost-effective strategy for the management of individuals at high risk of melanoma. There were also fewer invasive procedures in specialized surveillance compared with standard care in the community.
Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer
Authors: Beer Tomasz M. , Kwon Eugene D. , Drake Charles G. , Fizazi Karim , Logothetis Christopher , Gravis Gwenaelle , Ganju Vinod , Polikoff Jonathan , Saad Fred , Humanski Piotr , Piulats Josep M. , Gonzalez Mella Pablo , Ng Siobhan S. , Jaeger Dirk , Parnis Francis X. , Franke Fabio A. , Puente Javier , Carvajal Roman , Sengeløv Lisa , McHenry M. Brent , Varma Arvind , van den Eertwegh Alfonsus J. , Gerritsen Winald
Published: October 2016

Purpose

Ipilimumab increases antitumor T-cell responses by binding to cytotoxic T-lymphocyte antigen 4. We evaluated treatment with ipilimumab in asymptomatic or minimally symptomatic patients with chemotherapy-naive metastatic castration-resistant prostate cancer without visceral metastases.

Patients and Methods

In this multicenter, double-blind, phase III trial, patients were randomly assigned (2:1) to ipilimumab 10 mg/kg or placebo every 3 weeks for up to four doses. Ipilimumab 10 mg/kg or placebo maintenance therapy was administered to nonprogressing patients every 3 months. The primary end point was overall survival (OS).

Results

Four hundred patients were randomly assigned to ipilimumab and 202 to placebo; 399 were treated with ipilimumab and 199 with placebo. Median OS was 28.7 months (95% CI, 24.5 to 32.5 months) in the ipilimumab arm versus 29.7 months (95% CI, 26.1 to 34.2 months) in the placebo arm (hazard ratio, 1.11; 95.87% CI, 0.88 to 1.39; P = .3667). Median progression-free survival was 5.6 months in the ipilimumab arm versus 3.8 with placebo arm (hazard ratio, 0.67; 95.87% CI, 0.55 to 0.81). Exploratory analyses showed a higher prostate-specific antigen response rate with ipilimumab (23%) than with placebo (8%). Diarrhea (15%) was the only grade 3 to 4 treatment-related adverse event (AE) reported in ≥ 10% of ipilimumab-treated patients. Nine (2%) deaths occurred in the ipilimumab arm due to treatment-related AEs; no deaths occurred in the placebo arm. Immune-related grade 3 to 4 AEs occurred in 31% and 2% of patients, respectively.

Conclusion

Ipilimumab did not improve OS in patients with metastatic castration-resistant prostate cancer. The observed increases in progression-free survival and prostate-specific antigen response rates suggest antitumor activity in a patient subset.
Ocular Salvage and Vision Preservation Using a Topotecan-Based Regimen for Advanced Intraocular Retinoblastoma
Authors: Brennan Rachel C. , Qaddoumi Ibrahim , Mao Shenghua , Wu Jianrong , Billups Catherine A. , Stewart Clinton F. , Hoehn Mary Ellen , Rodriguez-Galindo Carlos , Wilson Matthew W.
Published: October 2016

Purpose

To evaluate topotecan-based therapy for advanced intraocular retinoblastoma.

Patients and Methods

Twenty-seven patients with bilateral retinoblastoma (male patients, n = 14; median age, 8.4 months) received chemotherapy: two courses of topotecan plus vincristine followed by three alternating administrations of carboplatin and vincristine for two courses and topotecan plus vincristine for one course, with optional periocular carboplatin. Focal therapy was applied after cycle 2. Event-free survival was defined as avoidance of external-beam radiotherapy (EBRT) and enucleation.

Results

Of 54 eyes, 42 were Reese-Ellsworth group IV to V, and 37 were International Classification of Retinoblastoma group C to E. Eleven eyes were enucleated: one at diagnosis, nine with progressive disease including three eyes treated with EBRT, and one that developed neovascular glaucoma after completion of therapy. One patient was removed from protocol with prolonged infection in course 1; 26 patients (51 eyes) were analyzed. At 10 years, cumulative incidence of EBRT was 5.9% (SE ± 3), and event-free survival was 69.2% (SE ± 27.2). Ocular survival for Reese-Ellsworth group IV to V eyes was 77.5% (SE ± 21.2); it was 74.3% (SE ≥ 18.8) for International Classification group C to E eyes. Vision testing (median age, 7 years; range, 5 to 10 years) documented 20/70 vision or better in one eye of 23 patients; 19 (76%) of 25 patients demonstrated 20/40 vision or better in one eye. All patients experienced thrombocytopenia (41 episodes in 275 courses; 15%). There were 29 episodes of febrile neutropenia (10%). Grade 3 diarrhea was present in nine of 27 patients, and one patient had an allergic reaction to carboplatin. All patients are alive at median follow-up 7.4 years (range, 2.7 to 10 years).

Conclusion

Topotecan combined with vincristine, carboplatin, and aggressive focal therapies is an effective regimen for the treatment of advanced retinoblastoma and results in globe salvage with vision. Toxicities were anticipated and managed with appropriate supportive care.
Management of Malignant Peritoneal Mesothelioma Using Cytoreductive Surgery and Perioperative Chemotherapy
Authors: Sugarbaker Paul H. , Turaga Kiran K. , Alexander H. Richard , Deraco Marcello , Hesdorffer Mary
Published: October 2016

Malignant peritoneal mesothelioma is a rare disease, with approximately 800 new patients per year in the United States. Its natural history is defined by progression restricted to the peritoneal space. In the past, patients with this disease had a limited lifespan of approximately 1 year. Numerous single-institution studies as well as a systematic review have reported median survival of 3 to 5 years with a combination of cytoreductive surgery and hyperthermic perioperative chemotherapy. These markedly improved survival statistics were achieved in experienced centers with 1% mortality and 20% morbidity rates. Data have shown that knowledgeable patient selection is required to prevent patients unlikely to benefit from undergoing these interventions. The conclusion is that patients with peritoneal mesothelioma can experience long-term progression-free survival or significant palliation with cytoreductive surgery plus hyperthermic perioperative chemotherapy. This management plan should be considered the standard of care for properly selected patients with malignant peritoneal mesothelioma at experienced centers around the world.
Treatment Prices at the Point of Care in a Clinical Oncology Service: Pilot Project
Authors: Henrikson Nora B. , Lau Rebecca W. , Tuzzio Leah , Christianson Matthew , Phan Thanh-Hien , Chen Eric
Published: October 2016

Purpose:

Patients with cancer increasingly wish to discuss cancer care costs with clinicians. We aimed to improve clinician access to treatment prices.

Methods:

We developed a pilot tool and accompanying workflow for four oncology clinics in an integrated care system. The online tool included 50 printable worksheets for cancer treatment protocols and was accessible directly from the electronic health record. Each sheet included codes and prices for all drugs and services for one treatment cycle in patient-friendly language. The worksheets did not provide patient-level cost-shares. We evaluated the resource’s launch, initial use, and acceptability through a convenience survey of initial users.

Results:

The project was successfully launched. Initial Web traffic to price sheets exceeded the number of treatments ordered during the launch period. One third of survey respondents reported use of the cost sheets at least once a week. The most useful features were improved access to cost information, treatment protocol–based layout, and ability to meet patient needs. The resource was rated as generally high value to patients, staff, and the organization. Suggested improvements included provision of patient-level cost sharing (63%) followed by expansion of the project to include more protocols (33%). These improvements are in progress.

Conclusion:

The pilot was feasible, built capacity to locate price data, and did not adversely affect staff workload. It addressed a clear need and demonstrated high potential overall value, especially with its protocol-based format. The resource’s lack of personalized estimates of out-of-pocket charges was the biggest gap reported.
Preparing for Value-Based Payment: A Stepwise Approach for Cancer Centers
Authors: Adelson Kerin B. , Velji Salimah , Patel Kavita , Chaudhry Basit , Lyons Catherine , Lilenbaum Rogerio
Published: October 2016

Most cancer centers are ill-equipped to pursue value-based payment (VBP) because of limited information on their population’s cost of care. Herein, we outline the stepwise approach used by Smilow Cancer Hospital at Yale-New Haven in our pursuit of better value care. First, we addressed institutional barriers. A move toward value required demonstration to Yale-New Haven Health System leadership that OCM would improve patient care, fund new infrastructure, and provide the opportunity to gain experience with VBP without a major threat to the financial stability of the health system. We evaluated patterns of care and found that of patients presenting to the emergency department (ED), 88% were admitted, 62% arrived during the workday, and 50% could have been stabilized with urgent care services. Within 30 days of death, 27% were admitted to the intensive care unit, 38% presented to the ED, and 52% were admitted. To quantify total cost of care, we accessed the 5% Medicare Limited Data Set to map out total cost of care for patients receiving chemotherapy at Smilow Cancer Hospital. Costs increased as patients moved through 6-month episodes, used the ED (patients with two or more visits were twice as expensive as those with one or fewer), or died during an episode (costs were twice as high as episodes in which the patient lived). To determine strategic interventions to improve value, we targeted investments in urgent care to reduce ED utilization, care management to prevent hospital admissions, and referral to palliative care for clarification of goals of care and avoidance of costly futile treatment. Developing internal metrics to evaluate success will require monitoring our interventions by having utilization measures for each site of care and individual provider.
Mimesis and Monstrosity: T. J. Clark's Picasso and Truth
Authors: Eiland Howard
Published: October 2016

In the space of some thirty years, T. J. Clark's art writing has moved from the social history of art—something arising in reaction to formalist and “iconological” disciplines of the previous generation, with their characteristic claim of political and ideological neutrality—to a new defense of aesthetic distance directed against the current “regime of visual flow” and its comfortable assumptions about the artwork's necessary ideological bearing and belonging to the world. Remaining constant in his work through the years is not only a method of intensive close reading of visual images but a wide-ranging and engaged theory of modernism, one keyed to the question of mimesis in (a technological) modernity. Picasso is for Clark the representative modern painter, “the artist of the century,” whose constantly experimenting production influenced virtually all the other realms of modern art: with its radically ambiguous disposition of image space, cubism is the prototypical “theme of modernism.” Picasso and Truth focuses on the particular structure of spatiality that lends a deep-seated unity of concern to Picasso's oeuvre through all its manifest variation in style during his long career. This structure is termed “room-space.” Clark traces the development of Picasso's concern with interior and exterior space, with the problematic relation of proximity and alterity, surface and depth, in the postcubist phase of his painting, when the obsession with monster figurations of the nonhuman in humanity leads to the apocalyptic realism of Guernica.
CELL BATTERY NATURAL COLD FOR COOLING MILK ON FARMS
Authors: Козловцев  , Kozlovtsev Andrey , Квашенников  , Kvashennikov Vasiliy , Константинов  , Konstantinov Mikhail , Козловцева  , Kozlovtseva Svetlana
Published: October 2016

The purpose of the research is search and justification of new methods and scientific-methodological fundamentals of reducing energy cooling costs of production of dairy farms in the process of production and processing due to the wide use of natural cold. In recent years there has been a tendency to return of interest in the use of natural cold in the processing and storage of food. The increasing interest in the use of natural cold contributes, above all, the worsening energy problems. The growth of world industrial production requires ever-increasing consumption. This leads to a permanent increase in the cost of energy in agriculture is quite a big effect on the cost of the obtained production. The use of natural cold for cooling milk is a very common trend not only in research and in new ideas of inventors, but also in the production of refrigeration equipment. Use of natural cold are water dishes for dairy farms. Developed dishes simple in design, reliable in operation, does not require complex maintenance, durable and do not use electricity when frized ice and further cooling of milk. The use of such devices will reduce the cost of production and processing of milk on dairy farms and in processing enterprises, reduce the cost of labour staff.
MONITORING OF ENTOMOСOMPLEXES OF SOFT SPRING WHEAT IN THE FOREST-STEPPE OF SAMARA AREA
Authors: Каплин  , Kaplin Vladimir
Published: October 2016

The purpose of research is creation of conditions for the formation of self-regulating entomocomplexes in agrocenoses with a significant competitive relations in the cultivation of spring wheat in the non-use of insecticides against pests. Insects was collected with an entomological net for 25-50 flaps in triple repeated in period of vegetation of wheat. In the conditions of the non-use of insecticides of entomokomplexes included insects-phytophagous which are potential vectors of viruses, phytoplasmas; suctorial and gnawing phytofagous; insects are developing inwardly wheat stems; entomophagous. Entomophagous regulating the density of phytophagous were represented by predators and parasites. In 2013-2016 Phyllotreta vittula, Oscinella pusilla, O. frit had a high density in the stage of seedling growth, Haplothrips tritici – in the stage of stem elongation of spring wheat. Against pests of seedlings in terms of their high density recommended for pre-treatment of seeds of spring wheat before sowing by system insecticide Cruiser, KC, without a negative impact on useful entomofauna of the agro-ecosystems. To the head emergence stage of spring wheat and the beginning of oviposition of Haplothrips tritici, its population was effectively reduced by Aeolothrips pascidutus. Development of cereal aphids was annualy kept Hippodamia variegata (Coccinellidae).
INFLUENCE OF ABIOTIC FACTORS FOR PRODUCTION EFFICIENCY OF HONEY FROM CROPS IN A STEPPE ZONE OFSTEPPE VOLGA AREA
Authors: Еськов  , Eskov Ivan , Мельников  , Melnikov Aleksey , Теняева  , Tenyaeva Olga
Published: October 2016

The purpose of the research is to reveal the features of influence of abiotic factors on the melliferous capacity of the base field rotations and the productivity of bee families in the period of maintenance and the main honey flow in conditions of the Volga region. The experience was laid in 2012-2014 in the Saratov CIS-Volga region, in the town of Balashov. The air temperature was taken into account on the basis of his own observations, and was also used meteorological data of the weather station. In the flowering period of crops daily recorded daily air temperature (1200 hours). The results of observations of the honey yield of honeybees (Krajina breed of bees (karnika) – Apis mellifera carnica Pollm.) in the flowering period of the main agricultural crops – nectarines (legumes, Cruciferae and Polygonaceae) in the steppe zone of the Volga region. The studies were conducted in a stationary apiary, located at 100-150 m from the agrocoenosis. Provides data of daily gain or loss of honey from control hives. Tendencies of influence of meteorological conditions when applying temperature, rainfall and other abiotic factors on the data of the gain control of the honey of the hive in the steppe zone of the Lower Volga region. The highest intensity of the honey production by bees (1375,0-1428,5 g/day) is the daily air temperature is 26±0,70 C, humidity 57-59%, against short-term precipitation and wind speed of 2.8-3.2 m/s. Period sustainable honey collection, including the main honey collection (July 10 – August 10), coincides geographically with prevailing cold North and northeast winds, the negative effects of which are offset by the terrain of the steppe zone of the Lower Volga region.
SELECTION OF MEDIUM EARLY AND MID-SEASON VARIETIES OF POTATOES FOR THE STEPPE ZONE OF SOUTHERN URALS
Authors: Аминова  , Aminova Evgeniya , Мушинский  , Mushinskiy Aleksandr , Герасимова  , Gerasimova Elena
Published: October 2016

The purpose of research is to identify the most adaptive and productive varieties of potatoes for the steppe zone of Southern Urals. The experience was laid by one-factor circuit in 3-fold repetition. The studies were conducted for middle- and middle-early varieties of potatoes domestic and foreign selection. Determined yield, marketability, starch and dry content in potato tubers. At 4 years of data were allocated potato varieties – Artemis (57.8 t/ha), Aerrow (52.0 t/ha) and Romano (49.5 t/ha). Distinguished highest yield of marketable products varieties: Artemis – 97.9%, Tarasov – 97.7%, and Aerrow Romano – 97.4%. The starch content in tubers was measurable by 10.2% (Ed Scarlett) to 16.0% (Kovalenko Memory), and the dry matter content in tubers ranged from 15.6% (Ed Scarlett) to 23.8% (Memory Kovalenko).
ALFALFA PESTS IN SAMARA REGION FOREST-STEPPE
Authors: Перцева  , Pertseva Elena
Published: October 2016

The purpose of research is alfalfa yields increasing by crops of different ages in the conditions of forest-steppe of the Samara region. Field studies were carried out in breeding crop rotation of department introduction, selection of feed and oilseeds Volga research station named after P.N. Konstantinov in 2014. Entomofauna alfalfa crops of different varieties and ages were studied mowing butterfly net. More numerous entomofauna was recorded in crops of alfalfa 2011 compared with age-related crops in 2008. Specialized herbivores studied culture were found in the growing season 2014 agrocenoses alfalfa crops – alfalfa tolstonozhka (Bruchophagus roddi Guss), alfalfa semyaed (Tychius flavus), alfalfa weevils (Sitona humeralis Steph.), Alfalfa bug (Adelphocoris lineolatus Goeze), leaf alfalfa weevil larvae (Phytonomus variabilis Hbst.) and larvae of alfalfa bollworm (Heliothis viriplaca Hfn.). Forms relating to herbivores Polyphagous and Oligophagous cereals were also recorded. In addition agrocenoses met: Entomophages predator’s cocktsinellidy (Coccinellidae), different types of spiders (Arachnida) and representatives of the family of grasshoppers (Tettigonioidea). Large foliage of alfalfa plants was recorded under option Population 4. Several smaller foliage of plants observed in crops of alfalfa 2011 compared with planting in 2008. On the 3-year agrocenoses best foliage appeared on variety Guzel which had the lowest figures in the age crops. Alfalfa seed yields mainly depend on the age of the studied agrocenosis culture. Alfalfa crop given harvest seeds in 3.6-4.7 times more than the age-crops in 2008. The highest seed yield was obtained from the varieties of Emerald in 2008 and in 2011.
The Communicative Essence of the Phenomenon of Russian Pianism and Its Role in Contemporary Culture
Authors: Чупрова  , Chuprova I.
Published: October 2016

The article discusses the features of intercultural communication from the point of view of the philosophy of culture. We study the problem of interdisciplinarity the concept of “communication” in scientific knowledge. As a means of studying intercultural communication is applied axiological, hermeneutical approaches. Examines the impact of the information revolution on the environment and the essence of communication, the problem of perception and understanding. Analyzes the evolution of forms and types of communication, generating a qualitative change in the semantic aspect of the culture. We are comparing the ability of verbal and non-verbal aspects of communication, taking into account features of modern international cooperation, and analyzes the role of “soft power” of musical art as a method of semantic translation of axiomatics and value foundations of culture. An attempt of philosophical analysis of the phenomenon of communication in the field of musical-performing activity of the musician-the pianist as a means of discovering the existential possibilities of the performer and the listener.
Interculture Dialog in Foreign Language Teaching in Europe
Authors: Бердичевский  , Berdichevskiy Anatoliy
Published: October 2016

The article deals with the problems of modern methods of foreign language teaching. Analysing the state of foreign language teaching on the modern stage the author comes to the conclusion that the pure communicative methods do not satisfythe modern demands of foreign language studing in the changed conditions of Europe. With the aim of teaching Russian as a foreign language he of fers crossculture competence for the achievement of mutual understanding in crossculture dialogue. This aim will berealised in cross culture of foreign language teaching.
Personality as the Object of Designing a Pedagogical Technology in Foreign Language Education
Authors: Богатырёва  , Bogatyreva M.
Published: October 2016

Humanistic tendencies of FL education require a dramatic change in the

“didactic landscape” of technologies, their channeling into the professional’s

personality. The analysis of the strategic factors and scientific principles

of designing pedagogical technologies shows that the educational technology

is essentially anthropic and focused on the psychology of acquiring

knowledge and learnings skills. Given the “extra-subject” properties of the

FL learner, it involves managing educational activities in a reflexive way,

i.e. through the formation of critical and creative thinking, tactics of mental

activity and speech behavior. The essence of technology largely manifests

itself in the intensification of the process of FL learning / teaching by using

engineering technologies and is aimed at upgrading students’ intellectual

level,their responsibility, morality, willingness to accept challenges and

overcomehardships of life.
Wati (Piper methysticum) medicinal plant: The ethnobiological and ethnomedicinal values of the Marind tribe in Merauke, Papua, Indonesia
Authors: SUHARNO SUHARNO , TANJUNG ROSYE HEFMY RECHNELTY , SUFAATI SUPENI , AGUSTINI VERENA
Published: October 2016

Suharno, Tanjung RHR, Sufaati S, Agustini V. 2016. Wati (Piper methysticum L.) medicinal plant: The ethnobiological and ethnomedicinal values of the Marind tribe in Merauke, Papua, Indonesia. Biodiversitas 17: 814-822. Biological resources around neighborhood play important roles in the cultural development of the surrounding communities, including the use of plants. Wati (kava, Piper methysticum) is one of the species that has long been used as a traditional medicine and cultivated by Marind tribal community in the lowlands of Merauke, Papua. The aim of this study is to examine the use and domestication of wati plant by Marind tribe in Papua.Results of the study showed that wati plant has long been used by the Marind tribal community as a medicinal plant with high customary value. Each customary event includes wati plant as a complementary requirement for legitimate activities by the Marind tribe. It is the importance of customary values that led the domestication of wati plant done since 60 years ago on a small scale to eventually develop into plant called as â€œthe Marind peopleâ€™s goldâ€. Results of the observation showed that 93.8% of the Marind people have largely recognized wati plant, while 53.3% of the immigrant communities from outside the area recognized it, but only 33.3% knew about its utilization. Although not all indigenous elders cultivate it, they recognize, utilize, and understand the rules of using wati plant in traditional events and as traditional medicine. As traditional medicine, the parts used by Marind people use root (100.0%), stem (96.6%), and leaves (89.7%). For customary events, the most important parts are the whole plant (100.0%), stem (100.0%), leaves (98.3%) and roots (93.1%). Their children even recognize it and know its benefits, but most of them 31.25% only utilize it but are prohibited from participating in its preparation (0.0%). The domestication of this plant is quite unique because it is closed to the public and is still done by a conventional method.
Relationality, entangled practices and psychosocial exploration of intergenerational dynamics in sustainable energy studies
Authors: Henwood Karen , Groves Chris , Shirani Fiona
Published: October 2016

Extensive knowledge exists regarding how to comprehend the embeddedness of everyday energy usage and resultant demand trajectories within wider social and material contexts. Researchers have explored how people find themselves locked into everyday ways of using energy, and how energy systems have evolved to entangle together practices and sociotechnological infrastructures. There is widespread acceptance that the challenges of transforming inconspicuous habitual ways of using energy require research attention. What is less clear is how to approach the study of everyday energy use to reflect the ways in which people make their daily lives meaningful. This article draws on sociological studies of family life and psychosocial research to thicken existing research on material infrastructures and social practices in energy use and demand reduction studies. Findings concern how relational entanglements have a bearing on everyday practices involving energy, with significant potential to deepen understanding of historically embedded change in people’s everyday energy dependencies.
Families in an environmental context
Authors: Uzzell David
Published: October 2016

Research on children’s learning in museums, children’s attempts to change their parents’ environmental practices, and how the different ‘logics’ of home and the workplace affect offshore oil workers’ transfer of environmental practices between the two, all focus on the critical role of the family in environmental change. This Open Space piece reflects on how environmental practices are strongly influenced by the family and the other institutions with which the family interacts.