bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Daidzein Against Rotenone Induced Parkinson’s Disease and a Potential Involvement of Mitochondrial Biogenesis.
Authors: Peshattiwar Vaibhavi , Muke Suraj , Kaikini Aakruti , Bagle Sneha , Dighe Vikas , Sathaye Sadhana
Published: October 2021

Parkinson’s disease (PD) ranks as second most prevalent neurodegenerative disorder but is devoid of neuroprotective treatment. Approaches with disease modifying ability with symptomatic relief has become an utmost necessity. Further multifactorial nature of PD presents challenges for efficacy evaluation of any potential test compound. The stated study makes an attempt to address these issues by employing a rotenone induced PD model involving a bilateral intranigral stereotactic rotenone injection for evaluation of the neuroprotective efficacy of Daidzein (DZ). DZ a soy isoflavone, is known for its various health benefits viz. immunomodulation, cardiovascular effects etc. In this study, animals after intranigral rotenone (12 μg) injection, were treated with DZ at a dose of 5, 10 and 20 mg/kg for 30 days. The neurobehavioural evaluation comprised of Rota-rod, Open field and Barnes maze test. The biochemical analysis constituting oxidative stress (Reduced glutathione, superoxide dismutase, catalase and lipid peroxidation), inflammation (TNF-α), mitochondrial alteration (complex I activity and biogenesis) was conducted on mid-brain tissue after 30 days of treatment. The SN and striatum was also subjected to immunohistochemical analysis (IHC) for TH positive neurons and Glial Fibrillary Acidic Protein. The analysis revealed significant improvement by daidzein in motor co-ordination and attenuation in cognitive deficits due to rotenone. The biochemical assessment exhibited significant decrement in oxidative stress as well as inflammation. DZ treatment also prevented complex I inhibition and promoted mitochondrial biogenesis eventually contributing to the neuroprotection apparent in IHC. Thus, the results strongly corroborate the neuroprotective potential of DZ against rotenone induced model of PD.
44/47 Scandium Labelled Cholecystokinin Derivative for Cancer Theragnostics
Authors: Cho Eun-ha , Lim Jae‑cheong , Lee So‑young , Park Ul-jae
Published: October 2021

The cholecystokinin (CCK) receptors are known to overexpress in various types of tumors. Through a previous study, a cyclic CCK analogue, DOTA-[Nle]-cCCK, was confirmed to have high in vivo stability and the tumor target ability of DOTA-[Nle]-cCCK capable of binding to the CCK receptor was confirmed through Lu-177 labeling. In this study, DOTA-[Nle]-cCCK was labeled with the pair-isotope, Sc-44/47, to confirm a technology that possibly could be applicable to radiopharmaceutical. First, we confirmed that the CCK receptor was overexpressed in AR42J, a cancer cell overexpressed in cancer tissue, and measured the binding ability of the receptor and DOTA-[Nle]-cCCK. We established the labeling method of radioactive scandium, and we confirmed that the Sc-44 labeled DOTA-[Nle]-cCCK administered to mice remained mostly in the bladder within an hour. Cell experiments with Sc-47 labeled DOTA-[Nle]-cCCK confirmed that more than half of the cancer cells were killed at a concentration of 5 MBq/ml. Through this study, we were able to confirm the diagnostic/therapeutic applicability of the DOTA-[Nle]-cCCK label with pair-isotope Sc-44/47.
Litter Mixing Effect On Decomposition Rate And Nutrient Release: Low-Quality Leaves of Coastal Species
Authors: Ndayambaje Patrick , Wei Lili , Zhang Tingfeng , Liu Lin , Huang Xu , Li Jie , Tian Shaohua , Xin Yu , Sun Xuecong , Liu Chaoxiang
Published: October 2021

Coastal wetlands are among the most carbon-rich ecosystems in the world. Litter decomposition is a major process controlling soil carbon input. Litter mixing has shown a non-additive effect on the litter decomposition of terrestrial plants particularly of those species having contrasting litter quality. But the non-additive effect has been rarely tested in coastal plants. We selected three common mangrove species and one saltmarsh species, co-occurring in subtropical coasts, to test whether the non-additive effect occurs when the litters of these coastal species mixing together. We are also concerned whether the changes in the decomposition rate of litter will affect the nutrient contents in waters. A litter-bag experiment was carried out in a glasshouse with single and mixed leaf litters. A non-additive effect was observed in the litter mixtures of mangrove species Aegiceras corniculatum vs. Kandelia obovata (antagonistic) and A. corniculatum vs. Avicennia marina (synergistic). Whereas, the mixture of A. corniculatum (mangrove species) and Spartina alterniflora (saltmarsh species) showed an additive effect. The strength of the non-additive effect was unrelated to the initial trait dissimilarity of litters. Instead, the decomposition rate and mass remaining of litter mixtures were strongly related to the carbon concentrations in litters. Nutrient content in waters was dependent on the decomposition rate of litter mixtures but not on the initial nutrient concentrations in litters. Despite the behind mechanisms were not yet revealed by the current study, these findings have improved our understanding of the litter decomposition of coastal species and the consequent nutrient release.
Investigating the Effectiveness of an Augmented Reality Game to Enhance the Mathematics Learning Experience of Dyscalculic
Authors: Debnath Tanmay
Published: October 2021

Dyscalculic face a condition where they are unable to comprehend mathematical information. One of the main causes attributed to the same is the poor experience level at various levels of education. The main aim of this study is to design and implement augmented reality (AR) games, by integrating a visual method of performing mathematical operations, for enhancing the experience of Dyscalculic. S total of 31 participants was involved in this study. An online survey was conducted to measure the effectiveness of the developed AR game. The results of the paired-sample T-test indicated that participants in the experimental group have enhanced their mathematical performance level with a substantial decrease in the mean problem-solving time. The findings demonstrate that the proposed game can effectively enhance the performance of the dyscalculic using visual cue representation.
Initial tightening of a cylinder head assembly on a marine engine block
Authors: Turof Mihaela
Published: October 2021

When attaching the cylinder head to the engine block, to internal combustion engines, the force with which the mounting screws are tightened is of particular importance (in case of too tight a tightening the screws may break, and in the case of too small tightening the fluid may leave the container due to removal. the flanges one to the other). In the case of slow, high-power engines, the engine block is individual, containing a single cylinder shirt. The intermediate solution of the engine block for a group of cylinders is also used. The two-stroke engine chops are more strongly heat demanded, due to the doubling of the number of cycles in the unit of time, respectively by combustion processes in the unit of time. Requesting the cylinder head bolts and other components of the assembly by force due to the pressure developed during the process of gas exchange and combustion in the engine cylinders is a demand with a pulsating character.
Improve channel signal quality using adaptive filters
Authors: Travediu Ana-Maria
Published: October 2021

A channel can be modelled by trying to calculate the physical processes which modify the transmitted signal. In this article we simulated the adaptive equalization of some communication channels. A system of data transmission in the basic band will be considered in order to illustrate the principle of adaptive equalization. In such a system, the data sequence is applied, upon emission, to a formation filter( low pass filter), with the purpose of limiting the occupied bandwidth. A relatively wide band noise is also introduced on the communication channel. The transmission channel can also be modelled as a linear filter, this is represented by the distortion filter. We used another filter to avoid the distortion introduced by the channel, with the role of equalizer. This should compensate for the distortion introduced by the channel. The channel transfer function is not generally known, and in addition, it may vary slowly over time. Therefore, the need for this filter appears to be adaptive. In order to perform the adaptation initially, a training sequence, known at the reception, can be transmitted first and the output of the filter is compared with a locally generated reference signal, but identical to the one emitted. After this initial adaptation phase, the transmitter transmits the information symbols, the useful signal, thus the application can be used to improve the signal quality of maritime communications channels.
Analysis of the adjustment of the speed of naval electric motors and its role
Authors: Iorgulescu Dumitru
Published: October 2021

The paper presents the advantages and disadvantages of the electric propulsion and the speed adjustment of the electric motors used for it. Using the speed regulation methods of D.C. and C.A. motors, we analyze the role of physical size that appear in mathematical relations. The speed adjustment methods for three-phase asynchronous motors are: changing the number of pairs of poles; alteration the frequency of the supply voltage; turning of the slip that is realized by the variation of the rotor resistance and alteration of the supply voltage. The voltage alteration is only effective during the load operation. The speed control is analyzed by modifying the number of pairs of poles, adjusting the speed by changing the frequency of the supply voltage, adjusting the speed by modifying the supply voltage, and adjusting the speed by rheostat adjustment. The speed adjustment of synchronous motors can only be done by varying the frequency of the supply voltage or by changing the number of pairs of poles. The role of adjusting the speed of the electric motors in propulsions is presented .
Aspects of the evolution of transportation of goods through the Suez Canal in the context of the modernization of canal
Authors: Anghel : Arlette Rabela
Published: October 2021

In the context of the modernisation of the Suez Canal, I considered important to conduct a study regarding the evolution of goods transport through the Suez Canal. This paper presents a comparative analysis in termes of new technical specifications and rules of sailing, as well as the evolution of maritime traffic, Net Tonnages and the decreasing of shipping routes.
Revisions of the SMS maintenance procedures based on computerized PMS data
Authors: Stazić Ladislav
Published: October 2021

According to the International Safety Management Code, every cargo ships of 500 gross tons and over must establish Ship Safety Management System that is documented in a Safety Management Manual. This document is prepared by the Company and contains rules regarding maintenance of the equipment, particularly recognized critical equipment. Those rules must be included into ship’s Planned Maintenance System, another requirement of the ISM Code. Maintenance periods in rules are based on several factors, while the Company experience in the operation and maintenance of the ship and its machinery and equipment is emphasized and analyzed in this paper. Analysis of records from different Computerized Planned Maintenance Systems obtained from several companies show that each company implemented their experience in the system. At the same time, the results show that very few modification of machinery maintenance intervals have been made with the proactive approach based on acquired experience and new knowledge.
Long‐Term Broadcast and Banded Phosphorus Fertilization of Corn Produced Using Two Tillage Systems
Authors: Howard Donald D. , Essington Michael E. , Logan Joanne
Published: October 2021

Surface‐broadcasting P is a management concern in no‐till (NT) corn (Zea mays L.) production. Field research was established in 1983 and continued through 1993 to evaluate broadcast and banded P applications for corn produced utilizing NT and disk‐till (DT) systems on a Loring silt loam (Oxyaquic Fragiudalfs). A wheat (Triticum aestivum L.) cover was established each fall. The tillage systems were main plots with a factorial arrangement of broadcast P rates, and the N + P band treatments were subplots. Annual broadcast P rates were 0, 20, 39, and 59 kg ha−1 A 22–20–0 kg ha−1 N + P band was applied after planting. All plots received a total of 168 kg N ha−1 each year. Disk‐till yields were higher than NT yields for 5 of the 11 yr and were increased by P rates up to 39 kg ha−1. No‐till yields were increased with P rates up to 20 kg ha−1. Yield response to banding N + P was inconsistent with year, tillage, and P rates. Three banded N + P plus broadcast P combinations equal to a broadcast P rate were applied each of the 11 yr. Yields for 5 of the 33 comparisons were increased by the banded plus broadcast P combination while three yields were reduced relative to broadcasting equal P rates. Yields for the other 25 comparisons were similar. Extractable P (EP) was increased with increased broadcast P rates, but the yield response was generally restricted to low EP situations.
Within‐Row Plant Spacing Variability Does Not Affect Corn Yield
Authors: Liu Weidong , Tollenaar Matthijs , Stewart Greg , Deen William
Published: October 2021

Nonuniform plant spacing within the row in corn (Zea mays L.) may reduce grain yield. To investigate the response of corn to plant spacing variability, experiments were conducted at two locations in south‐central Ontario during 2000 and 2001. Six plant spacing treatments, 6.7 to 16.2 cm in standard deviations (SD), were established by planting Roundup Ready corn with increasing proportions of conventional corn seeds and then removing the conventional corn using glyphosate before three‐leaf stage. Using SD as well as short gap, long gap, double, and cluster as an index of plant spacing variability, effects of plant spacing variability on corn growth and grain yield were investigated. Averaged across locations and years, grain yield was not significantly affected by plant spacing variability. Plant spacing variability also had no significant effect on leaf number, plant height, leaf area index, and harvest index. There were no correlations between plant spacing variability and stalk lodging and barren or double ears. The lack of strong correlations among plant growth, grain yield, and plant spacing variability indicates that spacing uniformity within the range used in this study is not a significant factor in determining grain yield under commercial conditions and common plant densities used in Ontario.
PORTABLE HYPERSPECTRAL TUNABLE IMAGING SYSTEM (PHyTIS) FOR PRECISION AGRICULTURE
Authors: Fitzgerald Glenn J.
Published: October 2021

Hyperspectral remote sensing can provide contiguous spectra of scenes made up of dozens to hundreds of narrow wavebands, across the visible and near‐infrared portions of the spectrum. This emerging technology provides spatial and spectral information that can be acquired simultaneously. Presented here for use in agricultural research is the Portable Hyperspectral Tunable Imaging System (PHyTIS). It is a computer‐controlled, liquid‐crystal tunable filter, digital imaging system designed to extract spectra of typical agronomic scene components (endmembers) such as sunlit and shaded leaves and soil for spectral mixture analysis. Results from a scene acquired in a cotton (Gossypium hirsutum L.) field showed that scene components could be successfully unmixed and area of each quantified. Image processing and hyperspectral remote sensing can identify endmembers to quantify crop biophysical parameters, to derive fractional cover maps, and could be used as inputs to plant, soil, and evapotranspiration models.
Effect of organic minerals and alpha-ketoglutarate in pheasant diet on performance, hatchability and the composition of eggs
Authors: FLIS MARIAN , GUGAŁA DARIUSZ
Published: October 2021

This study determined the effect of supplementation of the pheasant diet with mineral components (Ca, Fe, Zn and Cu) from organic sources with or without the addition of alpha-ketoglutarate (AKG) on productivity, hatchability parameters, nutrients and mineral content in pheasant eggs. Studies were performed on three groups of laying pheasants, which were kept in aviaries and received a standard mixture (Group I, the control group), a mixture with Ca, Fe, Zn, and Cu glycinates which replaced 50% of the mineral components in inorganic form (Group II), or a mixture with chelates and a 200 mg alpha-ketoglutarate supplement (Group III). Supplementation of the diet with chelates raised the content level of the mineral components in the whole egg and yolk, mainly the contents of calcium, zinc and iron. The addition of 200 mg of alpha-ketoglutarate to the diet with calcium, zinc, iron and copper chelates of glycine (50% of the supplemented elements) resulted in improved laying capacity and rates of reproduction and rearing of chicks, with a slight decrease in the size and weight of eggs. The eggshell was thinner, and the albumen and the Haugh Unit score were higher. Inorganic mineral components can be replaced by glycine chelates at up to 50%, especially with the addition of 200 mg of AKG, in the pheasant diet in commercial breeding.
Characteristics and prediction of subclinical hypocalcemia in dairy cows during the transition period using blood analytes
Authors: MA XINRU , GAO CHANGHONG , YANG MINGMAO , ZHANG BINGBING , XU CHUANG , YANG WEI
Published: October 2021

This study aimed to present the characteristics of and to predict subclinical hypocalcemia in dairy cows during the transition period using blood analytes. We examined fluctuations in plasma calcium (Ca), phosphorus (P), bone metabolic markers carboxy-terminal telopeptide of type I collagen (CTX), fibroblast growth factor (FGF23), 1,25(OH)2D3, parathyroid hormone, and other blood biochemical analytes from prepartum week 2 to postpartum day 14 in 116 multiparous high-producing Holstein cows from a free-stall barn dairy farm. With a plasma concentration of Ca <2.0 mmol/L as a criterion for the diagnosis of subclinical hypocalcemia, 64 cows were classified as normocalcemic, and 52 cows as subclinically hypocalcemic. Among the 52 hypocalcemic cows, 50 were detected on postpartum days 1 or 3, and 2 on postpartum day. The subclinically hypocalcemic cows were in a state of low bone turnover in the prepartum period, with low plasma concentrations of Ca and CTX. The subclinically hypocalcemic cows showed signs of a P regulation disorder in the prepartum period. This was marked by high plasma concentrations of P and low concentrations of 1,25(OH)2D3 and FGF23, which is also considered to be the cause of the low bone turnover. The results of a multiple logistic regression model showed that prepartum plasma concentrations of FGF23, CTX, and Ca were ideal predictors of postpartum subclinical hypocalcemia in dairy cows, using the model equation 38.8-0.052*FGF23-0.492*CTX-10.645*Ca, with a score of > 0 considered as an indication of increased risk of subclinical hypocalcemia after calving. The scoring rule had an accuracy of 79.3%, sensitivity of 76.9%, and specificity of 81.3%. The plasma concentrations of FGF23, CTX, and Ca were ideal predictors of postpartum subclinical hypocalcemia in dairy cows.
OTIMIZAÇÃO DE PARÂMETROS DE PROJETO DE ATENUADOR DINÂMICO SINCRONIZADO (ADS) PARA REDUÇÃO DO STORY DRIFT EM EDIFÍCIO
Authors: Brandão Francisco da Silva , Miguel Letícia Fleck Fadel
Published: October 2021

Este trabalho apresenta um estudo sobre a otimização dos parâmetros de projeto de um Atenuador Dinâmico Sincronizado (ADS) utilizado em um edifício submetido à excitação sísmica, visando o controle de sua resposta dinâmica. A estrutura analisada possui 22 andares e foi modelada com elementos de barra de pórtico plano. O sismo aplicado trata-se de um registro real com PGA 0,4g. A resposta dinâmica foi avaliada em termos dos máximos deslocamentos relativos entre pavimentos (story drift), com base em um critério normativo. Para o dimensionamento do ADS são considerados dois métodos clássicos e um método otimizado cujos parâmetros são obtidos através de algoritmo meta-heurístico. Os resultados obtidos mostraram que todos os métodos foram eficientes na redução da resposta da estrutura e sua adequação ao critério de norma, contudo, o método otimizado apresentou as melhores reduções, sendo, portanto, a solução ótima.
ESTIMAÇÃO ESTATÍSTICA DA INTENSIDADE DE TRÁFEGO EM FILAS MARKOVIANAS COM UM ÚNICO SERVIDOR
Authors: Gomes Eriky S , Cruz Frederico R. B.
Published: October 2021

Um dos sistemas de filas mais simples conhecidos na teoria de filas são as filas markovianas com único servidor, ou seja, filas com chegadas segundo um processo de Poisson e tempos de serviço exponencialmente distribuídos, ou, na notação de Kendal, filas M=M=1. Apesar da sua simplicidade, as filas M=M=1 possuem importantes aplicações práticas. Assim elas são o foco desse artigo e são estudadas no aspecto de estimação estatística da sua intensidade de tráfego, que corresponde à fração do tempo que tais filas estão ocupadas. Importante por si só, a intensidade de tráfego permite ainda a dedução de outras medidas de desempenho importantes nos sistemas de filas, tais como o tamanho médio da fila ou o número esperado de usuários no sistema. Nesse estudo, a estimativa é feita baseada na observação do número de chegadas de clientes durante o tempo de atendimento de um cliente, uma forma bastante natural e prática de coleta de dados. É apresentada uma metodologia bayesiana para estimar o parâmetro de interesse, que é comparada com o clássico estimador de máxima verossimilhança (EMV). A abordagem proposta é analisada por meio de simulações Monte Carlo, para atestar sua eficiência, em que é demonstrado que o EMV apresenta uma maior variância, embora possa apresentar um menor vício, em amostras de tamanho pequeno (n < 50).
ANÁLISE ESTOCÁSTICA DE PROPAGAÇÃO DE DOENÇAS EPIDEMIOLÓGICAS
Authors: Borges Beatriz , Lima Roberta , Sampaio Rubens
Published: October 2021

Este trabalho analisa com uma abordagem estocástica a propagação de uma doença epidemiológica em uma população. O foco é caracterizar a evolução do número de infectados ao longo do tempo de um ponto de vista probabilístico, ou seja, caracterizar a propagação de incertezas no número de infectados. Para fazer essa análise, o número de indivíduos contaminados por cada membro já infectado da população é modelado como uma variável aleatória binomial(m; p) e a propagação da doença é modelada como um processo estocástico de ramificação. Um modelo estatístico é construído para esse processo de ramificação. Histogramas e estatísticas amostrais do número de infectados ao longo do tempo, como por exemplo, média e variância, são calculadas através de simulações de Monte Carlo para o processo de propagação da doença. Os objetivos do trabalho são comparar as estatísticas amostrais calculadas com previsões da literatura, e determinar a influência de parâmetros do modelo probabilístico da variável aleatória de contágio no processo de ramificação. Através dessas análises determina-se a probabilidade de extinção da doença.
UMA ANÁLISE DA INFLUÊNCIA DO NÚMERO DE REPRODUÇÃO DIÁRIO NOS CASOS DE COVID-19 NO RS
Authors: Mielke Letiane Ludwig , Pitol Lisandra , Buske Daniela , Athayde Alexandre , Piovesan Luciana Rossato , Gonçalves Glênio Aguiar , Quadros Régis Sperotto de
Published: October 2021

Aparentemente a ligação da matemática com a disseminação de doenças é algo bastante distante, porém isso não acontece quando se trata de estudos epidemiológicos. Estes são responsáveis por prever cenários e apontar possíveis medidas a serem tomadas em momentos de crise sanitária. Nesse sentido, o presente estudo tem como objetivo modelar os dados da COVID-19 fazendo uma análise da influência do número de reprodução diário no estado do Rio Grande do Sul. Utilizou-se o modelo matemático SIR para o estudo do comportamento da curva epidêmica da COVID-19 no estado, onde foram analisados os dados de 10 de março a 30 de setembro de 2020 e foram feitas projeções do provável comportamento desta data até 31 de dezembro de 2020. Os resultados da simulação mostraram que o número de reprodução diário estimado ao final do mês de setembro estava em torno de 0,9, podendo variar de 0,88 a 0,92, o que indicaria uma possível queda. Além disso, foi observado que os dados reais, ao final do mês de dezembro superaram as projeções, o que pode ser explicado, dentre outros motivos, pela não manutenção das mesmas condições epidemiológicas que eram observadas em setembro, mês em que foram feitas as análises e projeções apresentadas.
El abrigo de Haza La Viña: un yacimiento de arte rupestre esquemático en el valle del río Sorbe (Muriel, Guadalajara, España)
Authors: Triguero Ignacio , Luque Luis , Castillo-Jiménez Samuel , Alcaraz-Castaño Manuel
Published: October 2021

Se presenta un nuevo yacimiento de arte rupestre esquemático en el valle del río Sorbe, junto a la población de Muriel (Tamajón, Guadalajara). Se localiza en el interior de una covacha abovedada contigua a una cavidad de mayores dimensiones y contiene un único panel con un total de 6 unidades gráficas: cuatro antropomorfos y un signo en pintura roja en torno a dos cazoletas parcialmente superpuestas. En el centro de la península ibérica, junto a los grandes conjuntos esquemáticos de Valonsadero (Soria) y el Duratón (Segovia), se comienza a conformar un tercer grupo en la vertiente sur del sistema Central, del cual Haza la Viña constituye uno de sus ejemplos mejor conservados. Asimismo, la aparente sincronía de las representaciones permite ahondar en los esquemas compositivos de este horizonte gráfico, cuya cronología situamos en el Neolítico-Calcolítico. Se trata del único conjunto rupestre prehistórico conservado en la actualidad en este valle.
Aesthetic Factor of Customer Perception and Its Role in Managing Company Competitiveness
Authors: Afonsky S. A.
Published: October 2021

The article advances the idea about a drop in people interest in buying similar goods and services, especially in conditions of uncertainty, in particular corona-virus epidemic, when people care less about external things, such as their clothes for visiting public places. Today we observe the necessity in meeting aesthetic needs through different tools and artistic objects. Therefore, we can say that it is a certain return to those times, when in public places and even in the Underground you can see real works of art that were not made in a hurry, according to the principle ‘the cheaper the better', but those of full value. In spring 2021 we conducted a survey of students of the Russian Plekhanov University of Economics and the Arts College RGGU to find the role of the aesthetic (emotional, sensual) element - the art-object (in this case - a poster) - in conditions of uncertainty, i. e. COVID-19 epidemic. The findings of this research showed that aesthetic value of graphics takes a foreground, it should be connected with specialization of the trade enterprise, its historic and other factors. The author demonstrates that availability of aesthetic values can form a motivating platform for repeated visits to the store and thus shape its competitive advantage.
Acute Approaches to the Development of Closed Cycle Economy in the Field of Hard Communal Waste Treatment
Authors: Sukhorukov A. I. , Zakharova E. A.
Published: October 2021

By methods of analysis and synthesis the article studies the problem of developing closed cycle economy in the field of hard communal waste treatment (HCW). Dynamics of waste making up was analyzed and its physical and mechanic properties and chemical composition were provided. The article gives economic tools, functions and classification of these tools that are necessary to organize the process approach to management. The authors put forward a promising scheme of treating HCW built on the basis of European experience and worked out the acute functional-structural scheme of the treatment system by the HCW complex, which demonstrates key business processes and tools of management. Such complex approach to describing the system of HCW treatment can simplify digital modeling of multi-variant business processes, such as burial of waste at waste-grounds, utilization at waste-burning plants, sorting and recycling at waste-recycling enterprises. Digital modeling with successful automated functional and cost analysis can give an opportunity to decrease uncertainty in the field of economic efficiency of managerial decision-making for rational HCW treatment and development of closed cycle economy in this sphere. A correct choice of approaches to the development of closed cycle economy in the field of HCW treatment can reduce the load on nature and support health of people.
A Young Women with Infected Polycystic Lung Disease That Affects the Quality of Life
Authors: Suwandi Gede Sasmika , Djajalaksana Susanthy
Published: October 2021

Introduction: Polycystic lung disease (PLD) is a group of diseases with heterogeneous pathophysiological processes. The demographics and clinical symptoms vary widely. The etiology of PLD is related to neoplasms, genetics, lymphoproliferative disorders, infections, interstitial diseases, smoking, and developmental disorders. In HRCT, cystic, nodular, ground glass opacities and pneumothorax can be found. Tissue biopsy and immunohistochemistry are needed to determine the type of PLD. Age is very influential towards the survival rates, rapid decline in lung function often occurs at a young age, thus, causing long-term complications in the cardiovascular systemCase Description: A 14-years-old woman complained of shortness of breath and cough was diagnosed with Poly cystic lung disease with Lung TB as secondary infection. CT Scan Thorax showed multiple cavities with consolidation, abdominal ultrasound of the ovary found a simple cystic lesion. The patient underwent TB treatment. After evaluation, clinical symptoms improved, but the patient is often absent from school, thus, indicating disruption in quality of life. Spirometry data showed decreased pulmonary function ad modum restriction, and moderate obstruction. The patient is planned to undergo several examinations such as Bodypletysmography, Bronchoscopy, and VATS to obtain tissue samples, so a diagnosis can be made. Considering the age of the patientâ€”who is still youngâ€”definitive therapy as a continuation is expected to improve the patient's quality of life.Conclusion: The diagnosis of PLD in the patient still requires further examination. Other tests, such as biopsy followed by immunohistochemical examination, can be used to confirm the type of PLD. Currently, the patient is undergoing TB treatment and routine control to the clinic. Ater treatment, the clinical symptoms alleviated, but shortness of breath is still present, especially felt after walking fast and carrying heavy loads. Spirometry was done as an evaluation of pulmonary function, showing moderate restriction and obstruction. It is clear that PLD affects the quality of life in this patient.
A Rehabilitation Program for Individuals With Chronic Low Back Pain: Protocol for a Randomized Clinical Trial
Authors: Junkes-Cunha Maíra , Sieczkowska Sofia Mendes , Vilarino Guilherme Torres , Bevilacqua Guilherme , Andrade Alexandro
Published: October 2021

Background

Low back pain (LBP) is the leading cause of disability worldwide. Physical exercise, as a treatment, is beneficial for the improvement of quality of life in patients with LBP, and it is widely accepted.

Objective

We aimed to develop a protocol for a feasibility study that is designed to compare the effectiveness of different interventions in reducing pain, functional, and psychosocial factors among patients with chronic LBP after 8 weeks of randomization.

Methods

This is a study protocol for a randomized controlled trial that will consist of individuals with chronic LBP who are aged between 18 and 65 years. Participants will be allocated, through block randomization, to one of the following groups: the motor control exercises (MCEs), pain education, MCEs+pain education, and usual care groups. The primary outcome will be pain intensity, and the secondary outcomes will be the pressure pain threshold, which will be measured with a digital algometer; LBP-related disability; fears and beliefs; the fear of movement; quality of life; mood states; and levels of depression and anxiety. The trial was approved by the ethics committee for research involving human beings of the Federal University of Pelotas (reference number: 5.717.390) in September 2022, and it will be conducted until August 2023.

Results

The researchers are being trained to apply the questionnaires and carry out the interventions. Patient recruitment will begin at the end of 2022 and results are expected to be achieved by August 2023.

Conclusions

Our trial will provide preliminary data regarding the feasibility and safety of MCEs and pain education for patients with LBP. It will also provide preliminary outcome data that can be used to identify the most efficient intervention and the level of health care that should be implemented in public health services.

Trial Registration

Brazilian Registry of Clinical Trials U1111-1221-4106; https://ensaiosclinicos.gov.br/rg/RBR-2xx2r2/

International Registered Report Identifier (IRRID)

PRR1-10.2196/31345
Government Responsiveness in the Prevention of Spreading Covid-19: Vietnam and Indonesia in Comparison
Authors: Yusuf M. , Muzwardi Ady , Syukri Muhammad
Published: October 2021

This study attempts to reveal the responsiveness of both Vietnam and Indonesia in anticipating the massive external shock that was Coronavirus-19. A change in external factors, such as pandemics, has challenged politicians and governments at large to be responsive in resolving problems quickly. Generally, recent research focused on reactive policies, disaster mitigation, and medical issues, while discussing government responsiveness in disease prevention is only covered in a few studies. This research uses a comparative qualitative method with an analysis period from December 2019 to the end of May 2020. The data is derived from various secondary information sources, such as research results, news, official reports, or government statements, which are interpreted through a systematic coding process to explain the phenomenon. The primary results showed that government responsiveness determines the success of handling the deadly coronavirus in pre-pandemic and current pandemic situations. A strong political will and leadership style is essential, and a solid bureaucratic apparatus in implementing policies and programs is decisive. As an authoritarian democracy, in collaboration with CDC, Vietnam was able to anticipate before the pandemic spread and succeeded in suppressing the spread after it was detected even though it had issued a blundering policy. Meanwhile, as a democratic country, Indonesia slowly responded to the outbreak by decision making where the pandemic is handled after it is detected and spread to various regions. The rulers tend to avoid the experts and growing opinions addressed to the government.
Effect of Physical Characteristics on Resident’s Satisfaction in a High-Density Area of Ilorin Metropolis
Authors:   Yaba College of Technology, Alabi Oluwole Titilayo , Kayode Sakariyau Jamiu ,   Abubakar Tafawa Balewa University, Misbahu AbdulKadir ,   Abubakar Tafawa Balewa University, Olaifa Oluwadare Joel ,   Joel Olaifa & Partners
Published: October 2021

This study looked at the impact of a resident’s physical attributes on housing satisfaction in Ilorin to figure out how to uncover the significant relationship in Ilorin. The research took a quantitative method. A questionnaire was designed and distributed to 126 household heads, with 94 responses. Households were polled using systematic random sampling to collect information on socio-economic variables and housing satisfaction. To analyze the effect of variables, the data were subjected to descriptive statistics and linear regression using SPSS. The study found that physical factors have a substantial impact on home satisfaction in the studied area. The study discovered that toilet facilities, rendered and painted walls, tiles, a well-equipped kitchen, no finishing wall, electricity and generator as an alternative means of lighting a kitchen without modern facilities, concrete, and a pit toilet are all factors that influence residents’ satisfaction. It was also discovered that the most excellent mean score was for bathroom facilities, rendered and painted walls, and tiles. It was suggested that the government make the missing social amenities available and rehabilitate the deteriorating ones as urgent. To improve resident satisfaction in the study region, proper routine management of social amenities should be done.
A EDUCAÇÃO E A MÍSTICA NO/DO MST:
Authors: Figueiredo Allan Diêgo Rodrigues , Silva André Gustavo Ferreira da
Published: October 2021

O presente artigo se inscreve na interface entre os Movimentos Sociais e a Educação, partindo da realidade da prática educativa da Mística do Movimento dos Trabalhadores Rurais Sem Terra (MST). A problemática que mobiliza esta reflexão é: quais as possíveis contribuições da Mística na perspectiva da educação emancipatória para o fortalecimento dos processos de formação humana no MST? O artigo tem como objetivo analisar as contribuições da Mística na perspectiva da educação emancipatória para o fortalecimento dos processos de formação humana no Movimento Sem Terra. Para tal itinerário, mobilizou-se a metodologia baseada na pesquisa bibliográfica. No desenvolvimento do percurso teórico-metodológico, fez-se uso das reflexões de autores abalizados nas discussões, tais como: Coelho (2010), Caldart (2012), Stedile e Fernandes (2012), Souza (2012), Moura (2019) e Figueiredo (2020). Por fim, concluiu-se que a Mística enquanto prática educativa possibilita o fortalecimento do processo de formação humana e identitária do povo político do MST e, ao mesmo tempo, a educação para a coletividade a qual torna consistente a existência e a mobilização organizativa e política do Movimento Sem Terra no decorrer da história e das lutas sociais por um projeto societário outro.
LA EDUCACIÓN MENSTRUAL COMO PROYECTO FEMINISTA DE INVESTIGACIÓN/ACCIÓN
Authors: Calafell Sala Núria
Published: October 2021

El presente artículo explora algunos de los fundamentos teórico-epistémicos que conforman la Educación Menstrual como proyecto feminista de investigación/acción. A partir de la observación participante, la interpretación de textos y la reconstrucción de un intinerario corporal con una de las informantes, realizado desde el año 2018, se propone un continuum entre aquellos antecedentes que inscriben a la Educación Menstrual en un largo recorrido de luchas por la salud y la liberación de las mujeres, y una serie de propuestas que un grupo de mujeres –situadas, principalmente, en la provincia argentina de Córdoba- han puesto en circulación en los últimos dos años, tanto en redes sociales como en proyectos formativos y materiales didácticos de manufactura propia. Los resultados muestran que la Educación Menstrual se revela como una práctica pedagógica colectiva y experimental, construida sobre un sincretismo en el que convergen argumentos científicos, espirituales y de la salud, leídos en clave feminista.
¿Son las investigadoras de Documentación más interdisciplinarias frente a sus colegas hombres? Un análisis aplicado al profesorado español
Authors: Blázquez Ochando Manuel , Montesi Michela , Villaseñor Rodríguez Isabel
Published: October 2021

La actividad científica desempeñada por mujeres difiere bajo varios puntos de vista de la de los hombres, tanto en términos de producción como de impacto. En este trabajo, comparamos la actividad científica de 349 profesores y profesoras del área de Biblioteconomía y Documentación (ByD) afiliados con universidades españolas, con base en el análisis de su trayectoria de publicación en revistas vaciadas en Scopus. Se analizan las publicaciones de la muestra atendiendo a tres indicadores de interdisciplinariedad (variedad, equilibrio y disparidad), y midiendo la disparidad a través de métodos de Procesamiento del Lenguaje Natural (PNL) y Recuperación de Información (RI). A pesar de no encontrar diferencias importantes en las tres dimensiones, los datos obtenidos apuntan a la posible inadecuación de los índices de citas de reflejar las actividades académica desempeñadas por las mujeres en toda su variedad, así como a la necesidad de comparar la producción de hombres y mujeres con base en el análisis temático de los contenidos producidos.
Primitive Beables Are Not Local Ontology: On the Relation between Primitive Ontology and Local Beables
Authors: Allori Valia
Published: October 2021

When discussing quantum ontology, the debate has recently focused on comparing and contrasting wavefunction realism and its rivals. Among them one finds the primitive ontology approach, which is often conflated with the local beables program. In this paper I wish to clarify what I take to be the distinction between the notion of primitive ontology and the one of local beable. I argue that the primitive ontology is the local beable which allows for a dynamical, constructive explanation which preserves symmetries.
The positive effect of perceived leader humor on negative workplace gossip
Authors: Shi Xiaojuan
Published: October 2021

The purpose of this study was to examine the positive relationship between employee perceived leader humor and employee negative workplace gossip about a leader (NWGL). Using a multiple time point investigation of leaders and followers (N = 168), I found that perceived leader
humor was positively related to NWGL and that employee perceived team inclusion mediated this relationship. Further, employee job security moderated the relationship between perceived leader humor and employee perceived team inclusion, and also moderated the mediating effect of employee perceived
team inclusion in the link between perceived leader humor and employee NWGL. These findings suggest that the beneficial effects of leader humor are not universal, and that the fostering of leader humor might have unintended negative consequences, that is, increased NWGL through employee perception
of team inclusion. Implications for theory and research are discussed.
Effects of applying the new ASBE 21 Leases on the financial statements: Evidence from China
Authors: Xu Yun , Rahman Md. Jahidur
Published: October 2021

The Ministry of Finance of China has proposed a new lease accounting model to the existing lease accounting standard that requires the capitalization of all operating leases as assets and liabilities. In this case study, the key effects of the application of a new accounting standard — Accounting Standard for Business Enterprises 21 (ASBE 21), on financial statements and financial ratios of listed companies in the Chinese air transport industry have been analyzed and investigated. Significant relative differences were found within the airline industry in China. Results indicated that the total assets and liabilities would increase due to the capitalization of operating leases, whereas the profitability of firms was expected to decrease. Furthermore, the coverage of firms would decline, but the leverage of these firms would be improved. Rather than China, prior studies have analyzed the firms in other countries, where different accounting principles are applied. Hence, this study can provide useful information for the investors, as well as other stakeholders that are interested in Chinese airline corporations, and help to complete the studies about different lease accounting standards applied in different countries.
Selective serotonin reuptake inhibitor use is associated with major bleeding during treatment with vitamin K antagonists: results of a cohort study
Authors: Bakker Sanne , Burggraaf Louise , Kruip MJHA , Meer Felix van der , Lijfering WM , Rein Nienke van
Published: October 2021

Aims: To determine whether Selective serotonin reuptake inhibitors
(SSRIs) cause major bleeding during vitamin K antagonist (VKA) treatment
and investigate the possible mechanisms behind this interaction.
Methods: Information on SSRI use and bleeding complications was obtained
from patient records at the Anticoagulation Clinics of Leiden and
Rotterdam of VKA initiators between 2006 and 2018. Conditional logistic
regression and time-dependent Cox regression were used to estimate the
effect of SSRIs on a high INR (≥ 5) within 2 months after SSRI
initiation and on major bleeding during the entire period of SSRI use,
respectively. SSRI use was stratified for (non-)CYP2C9 inhibitors.
Results: 58,918 patients were included, of whom 1504 were SSRI users.
SSRI initiation versus non-use was associated with a 2.41-fold (95%
confidence interval [CI] 2.01-2.89) increased risk for a high INR,
which was 3.14-fold (95%CI 1.33-7.43) among CYP2C9 inhibiting SSRIs.
SSRI use versus non-use was associated with a 1.22-fold (95%CI
0.99-1.50) increased risk for major bleeding in all SSRI users, which
was 1.31-fold (95%CI 0.62-2.72) in CYP2C9 inhibiting SSRIs compared to
non-users. Conclusion: SSRIs are associated with an increased risk of
high INR and major bleeding. These risks were slightly more elevated for
CYP2C9 inhibiting SSRI users, suggesting that this was due to a
pharmacokinetic interaction (by CYP2C9 inhibition) as well as a
pharmacodynamic effect of SSRIs on platelet activation.
Trends in hospitalization and factors associated with in-hospital death among pediatric admissions with implantable cardioverter defibrillators
Authors: Qasim Amna , Pham Tam Dan , Kim Jeffrey , Valdes Santiago , Howard Taylor , Diaz Matthew , Morris Shaine , Miyake Christina
Published: October 2021

Background: As pediatric implantable cardioverter defibrillator (ICD)
utilization increases, hospital admission rates will increase. Data
regarding hospitalizations among pediatric patients with ICDs is
lacking. In addition, hospital mortality rates are unknown. This study
aimed to evaluate 1) trends in hospitalization rates of admissions over
20 years, 2) hospital mortality, and 3) factors associated with hospital
mortality among pediatric admissions with ICDs. Methods: The Kids’
Inpatient Database (2000-2016) was used to identify all hospitalizations
with an existing ICD 20 years of age. ICD9/10 codes were used to
stratify admissions by underlying diagnostic category as: 1) congenital
heart disease (CHD), 2) primary arrhythmia, 3) primary cardiomyopathy,
or 4) other. Trends were analyzed using linear regression. Hospital and
patient characteristics among hospital deaths were compared to those
surviving to discharge using mixed multivariable logistic regression,
accounting for hospital clustering. Results: Of 42,570,716
hospitalizations, 4165 were admitted <21 years with an ICD.
ICD admissions increased four-fold (p = 0.002) between 2000-2016.
Hospital death occurred in 54 (1.3%). In multivariable analysis,
cardiomyopathy (OR 3.5, 95%CI 1.1–11.2, p=0.04) and CHD (OR 4.8,
95%CI 1.5–15.6, p=0.01) were significantly associated with mortality.
In further exploratory multivariable analysis incorporating a coexisting
diagnosis of heart failure, only the presence of heart failure remained
associated with mortality (OR 8.6, 95%CI 3.7-20.0, p<0.0001).
Conclusions: Pediatric ICD hospitalization are increasing over time and
hospital mortality is low (1.3%). Hospital mortality is associated with
cardiomyopathy or CHD; however, the underlying driver for in-hospital
death may be heart failure.