bluuebunny/crossref_metadata_2025 huggingface dataset:
Whole Genome Sequences of the Wildtype AU-1 Rotavirus A Strain: The Prototype of the AU-1-like Genotype Constellation
Authors: Agbemabiese Chantal Ama , Dennis Francis Ekow , Lartey Belinda Larteley , Damanka Susan Afua , Nakagomi Toyoko , Nakagomi Osamu , Armah George Enyimah
Published: September 2024

Most human rotaviruses belong to the Wa-like, DS-1-like, or AU-1-like genotype constellation. The AU-1-like constellation, albeit minor, captured attention because its prototype strain AU-1 originated from feline rotavirus, leading to the concept of interspecies transmission of rotavirus. The AU-1 genome sequence determined by various laboratories over the years has documented two conflicting VP7 sequences in the GenBank. As culture-adaptation may introduce changes in the viral genome, the original fecal (wild-type) and the seed stock of culture-adapted AU-1 genomes were sequenced using the Illumina’s MiSeq platform to determine the authentic AU-1 sequence and to identify what mutational changes were selected during cell-culture adaptation. The wild-type and culture-adapted AU-1 genomes were identical except for one VP4-P475L substitution. Their VP7 gene was 99.9% identical to the previously reported AU-1 VP7 under accession number AB792641 but only 92.5% to that under accession number D86271. Thus, the wild-type sequences determined in this study (accession numbers OR727616-OR727626) should be used as the reference. The VP4-P475L mutation was more likely incidental than inevitable during cell-culture adaptation. This was the first study in which the whole genomes of both wild-type and cultured RVA strains were simultaneously determined by deep sequencing.
Evaluation of a Quadrivalent Shigella flexneri Serotype 2a, 3a, 6, and Shigella sonnei O-Specific Polysaccharide and IpaB MAPS Vaccine
Authors: Boerth Emily M. , Gong Joyce , Roffler Becky , Hancock Zoe , Berger Lydia , Song Boni , Malley Sasha F. , MacLennan Calman A. , Zhang Fan , Malley Richard , Lu Ying-Jie
Published: September 2024

Background: Shigellosis is the leading cause of diarrheal deaths worldwide and is particularly dangerous in children under 5 years of age in low- and middle-income countries. Additionally, the rise in antibiotic resistance has highlighted the need for an effective Shigella vaccine. Previously, we have used the Multiple Antigen-Presenting System (MAPS) technology to generate monovalent and quadrivalent Salmonella MAPS vaccines that induce functional antibodies against Salmonella components. Methods: In this work, we detail the development of several monovalent vaccines using O-specific polysaccharides (OSPs) from four dominant serotypes, S. flexneri 2a, 3a, and 6, and S. sonnei. We tested several rhizavidin (rhavi) fusion proteins and selected a Shigella-specific protein IpaB. Quadrivalent MAPS were made with Rhavi-IpaB protein and tested in rabbits for immunogenicity. Results: Individual MAPS vaccines generated robust, functional antibody responses against both IpaB and the individual OSP component. Antibodies to IpaB were effective across Shigella serotypes. We also demonstrate that the OSP antibodies generated are specific to each homologous Shigella O type by performing ELISA and bactericidal assays. We combined the components of each MAPS vaccine to formulate a quadrivalent MAPS vaccine which elicited similar antibody and bactericidal responses compared to their monovalent counterparts. Finally, we show that the quadrivalent MAPS immune sera are functional against several clinical isolates of the serotypes used in the vaccine. Conclusions: This quadrivalent MAPS Shigella vaccine is immunogenicity and warrants further study.
Post-Transplantation Seroprotection Rates in Liver, Lung, and Heart Transplant Recipients Vaccinated Pre-Transplantation against Hepatitis B Virus and Invasive Pneumococcal Disease
Authors: Hornung Lise Bank , Hamm Sebastian Rask , Hald Annemette , Harboe Zitta Barrella , Lundbo Lene Fogt , Wareham Neval Ete , Heftdal Line Dam , Ekenberg Christina , Bjerrum Stephanie , Holler Jon Gitz , Mathiesen Inger Hee Mabuza , Krohn Paul Suno , Bjerring Peter Nissen , Gustafsson Finn , Perch Michael , Rasmussen Allan , Nielsen Susanne Dam
Published: September 2024

Vaccination before solid organ transplantation is recommended since post-transplantation immunosuppression is known to impair vaccine responses. However, little is known about post-transplantation seroprotection rates in organ transplant recipients vaccinated pre-transplantation. We aimed to investigate the proportion of transplant recipients vaccinated against hepatitis B virus (HBV) and invasive pneumococcal disease (IPD) pre-transplantation at the time of listing for transplantation with post-transplantation seroprotection. We included 136 solid organ transplant (SOT) recipients vaccinated at the time of listing for transplantation. We investigated post-transplantation antibody concentrations against HBV and IPD. Established antibody thresholds were used to define seroprotection. The proportions of SOT recipients with post-transplantation seroprotection were 27.9% (n = 38) and 42.6% (n = 58) against HBV and IPD, respectively. Compared to completing HBV vaccination pre-transplantation, completing post-transplantation vaccination (adjusted odds ratio (aOR): 7.8, 95% CI: 2.5–24.5, p < 0.001) and incomplete vaccination (aOR: 6.3, 95% CI: 1.2–32.6, p = 0.028) were associated with non-response against HBV, after adjustment for confounders. Importantly, patients with seroprotection at the time of listing had lower odds of non-response against HBV (aOR: 0.04, 95% CI: 0.0–0.1, p < 0.001) and IPD (aOR: 0.3, 95% CI: 0.1–0.7, p = 0.007) compared to those without seroprotection. SOT recipients vaccinated pre-transplantation had low post-transplantation seroprotection rates against HBV and IPD. However, SOT recipients with seroprotection at the time of listing had lower odds of non-response, suggesting early vaccination should be a priority.
Progress towards Measles and Rubella Elimination in the South-East Asia Region—2013–2023
Authors: Khanal Sudhir , Bura Vinod , Sangal Lucky , Sethi Raman , Dhongde Deepak , Bahl Sunil Kumar
Published: September 2024

The South-East Asia (SEA) Region of the World Health Organization (WHO), through a Regional Committee resolution in 2013, adopted the goal of “measles elimination and rubella control by 2020”. The goal was revised in 2019 to “measles and rubella elimination by 2023”. Countries of the Region have made significant efforts to achieve the goal. Progress has been made in the Region, with five of the 11 countries of the Region having been verified for having eliminated measles and rubella. Surveillance and immunization program performance for measles and rubella has shown an improvement since 2013. This progress has been possible due to a high level of political and programmatic commitment in the countries of the Region, as well as due to the alliances and infrastructures established for disease elimination initiatives in the past, notably for polio, being utilized effectively to implement strategies for measles and rubella elimination. The unforeseen COVID-19 pandemic had a detrimental effect on the immunization and surveillance efforts, leading to a delay in the achievement of measles and rubella elimination in the Region. Challenges to achieve the goal remain; however, efforts are ongoing in countries to not only protect the gains made so far but also to make further progress towards the goal of measles and rubella elimination.
Irrotational Flow over Ogee Spillway Crest: New Solution Method and Flow Geometry Analysis
Authors: Castro-Orgaz Oscar , Hager Willi H. , Guo Yakun , Erpicum Sebastien , Cantero-Chinchilla Francisco Nicolás
Published: September 2024

A spillway is a hydraulic structure of major importance in dam safety, and its current analysis usually involves a hybrid approach combining CFD modeling with experimental research, either using well-known WES design charts or conducting new model experiments in the laboratory. Flow over spillway crests involves fluid accelerations, making irrotationality an adequate simplification of the Navier–Stokes (NS) equations. However, an efficient tool using this method is currently lacking for spillway flow, particularly for ogee spillway flow. This work focuses on this aspect of the problem, and a new method for computing irrotational flow solutions over ogee spillways is proposed by developing flow net computational solutions. The proposed method entails a new iterative procedure in the complex potential plane where free surface pressures are exactly set to zero, contrary to other methods, and an automatic determination of the critical point, the unknown energy head, and the free surface profile. The model generates solutions efficiently in only a few seconds on a personal workstation, permitting a fast estimate of spillway flow operation, and is thus an effective complement to experimental and NS-CFD modeling. The solutions produced are compared with observations of a high operational head equal to five times the design head of the ogee crest, resulting in reasonable agreement. The application of the new model to investigate the limitations of analytical equations used in spillway flow, like Jaeger’s theory, establishes limits for its use by relating its curvature parameter to the spillway chute slope.
EstuarySAT Database Development of Harmonized Remote Sensing and Water Quality Data for Tidal and Estuarine Systems
Authors: Rego Steven A. , Detenbeck Naomi E. , Shen Xiao
Published: September 2024

Researchers and environmental managers need big datasets spanning long time periods to accurately assess current and historical water quality conditions in fresh and estuarine waters. Using remote sensing data, we can survey many water bodies simultaneously and evaluate water quality conditions with greater frequency. The combination of existing and historical water quality data with remote sensing imagery into a unified database allows researchers to improve remote sensing algorithms and improves understanding of mechanisms causing blooms. We report on the development of a water quality database “EstuarySAT” which combines data from the Sentinel-2 multi-spectral instrument (MSI) remote sensing platform and water quality data throughout the coastal USA. EstuarySAT builds upon an existing database and set of methods developed by the creators of AquaSat, whose region of interest is primarily larger freshwater lakes in the USA. Following the same basic methods, EstuarySAT utilizes open-source tools: R v. 3.24+ (statistical software), Python (dynamic programming environment), and Google Earth Engine (GEE) to develop a combined water quality data and remote sensing imagery database (EstuarySAT) for smaller coastal estuarine and freshwater tidal riverine systems. EstuarySAT fills a data gap that exists between freshwater and estuarine water bodies. We are able to evaluate smaller systems due to the higher spatial resolution of Sentinel-2 (10 m pixel image resolution) vs. the Landsat platform used by AquaSat (30 m pixel resolution). Sentinel-2 also has a more frequent revisit (overpass) schedule of every 5 to 10 days vs. Landsat 7 which is every 17 days. EstuarySAT incorporates publicly available water quality data from 23 individual water quality data sources spanning 1984–2021 and spatially matches them with Sentinel-2 imagery from 2015–2021. EstuarySAT currently contains 299,851 matched observations distributed across the coastal USA. EstuarySAT’s primary focus is on collecting chlorophyll data; however, it also contains other ancillary water quality data, including temperature, salinity, pH, dissolved oxygen, dissolved organic carbon, and turbidity (where available). As compared to other ocean color databases used for developing predictive chlorophyll algorithms, this coastal database contains spectral profiles more typical of CDOM-dominated systems. This database can assist researchers and managers in evaluating algal bloom causes and predicting the occurrence of future blooms.
Decontamination Potential of Ultraviolet Type C Radiation in Water Treatment Systems: Targeting Microbial Inactivation
Authors: Adeniyi Abayomi Olusegun , Jimoh Modupe Olufunmilayo
Published: September 2024

Access to safe water and sanitation is a critical global challenge, posing significant health risks worldwide due to waterborne diseases. This study investigates the efficacy of ultraviolet type C radiation as a disinfection method for improving water quality. The research elucidates UV-C’s mechanism of action, highlighting its ability to disrupt DNA and RNA replication, thereby inactivating pathogens. Furthermore, the study analyses the influence of key factors on UV-C disinfection effectiveness, including water turbidity and the presence of dissolved organic matter, which can attenuate UV-C penetration and reduce treatment efficiency. The experimental results demonstrate a substantial reduction in microbial content following UV-C treatment. River water samples exhibited a 57.143% reduction in microbial load, while well water samples showed a 50% reduction. Notably, Escherichia coli (E. coli) concentrations decreased significantly, with an 83.33% reduction in well water and a 62.5% reduction in borehole water. This study makes a novel contribution to the understanding of UV-C disinfection by identifying the presence of resistant organisms, including Adenoviruses, Bacterial spores, and the Protozoan Acanthamoeba, in water samples. This finding expands the scope of UV-C research beyond easily culturable bacteria. To address this challenge, future investigations should explore synergistic disinfection strategies, such as combining UV-C treatment with advanced oxidation processes. Optimising UV-C system designs and developing robust, real-time monitoring systems capable of detecting and quantifying known and emerging UV-resistant pathogens are crucial for ensuring comprehensive water decontamination.
An Urban Flood Model Development Coupling the 1D and 2D Model with Fixed-Time Synchronization
Authors: Sim Sang-Bo , Kim Hyung-Jun
Published: September 2024

Due to climate change, the frequency and intensity of torrential rainfall in urban areas are increasing, leading to more frequent flood damage. Consequently, there is a need for a rapid and accurate analysis of urban flood response capabilities. The dual-drainage model has been widely used for accurate flood analysis, with minimum time step synchronization being commonly adopted. However, this method has limitations in terms of speed. This study applied the hyper-connected solution for an urban flood (HC-SURF) model with fixed-time step flow synchronization, validated its accuracy using laboratory observation data, and tested its effectiveness in real urban watersheds with various synchronization times. Excellent performance was achieved in simulating real phenomena. In actual urban watersheds, as the synchronization time increased, the errors in surcharge and discharge also increased due to the inability to accurately reflect water level changes within the synchronization time; however, overall, they remained minimal. Therefore, the HC-SURF model is demonstrated as a useful tool for urban flood management that can be used to advantage in real-time flood forecasting and decision-making.
Morbidity and Water Quality: A Review with a Case Study in Tonosí, Panama
Authors: Gómez Zanetti Natasha A. , Olmos Guevara Jorge E. , Mack-Vergara Yazmin L.
Published: September 2024

Water quality concerns the physical, chemical, and biological factors that could negatively impact human health through its consumption, potentially causing infectious and chronic diseases due to immediate or prolonged exposure. In this context, the objective of this study is to identify diseases that are correlated with the quality of drinking water according to the literature. A systematic review was carried out considering academic and scientific documents from the last 6 years, including peer-reviewed research articles, books, and technical documents, such as standards and regulations related to public health and water quality. Subsequently, these results were applied to a case study from Tonosí (a district in Panama), where a drinking water quality assessment project was developed over the past two years including physicochemical, biological, inorganic chemical, and organic chemical analyses on drinking water during the rainy and dry seasons. Forty-five documents were obtained from the literature review and are presented in tables relating to diseases and water quality parameters. Based on the drinking water quality assessment results from Tonosí, the levels above and below the permissible range—according to the DGNTI-COPANIT 21-2019 Technical Regulation adopted by Panama as a drinking water quality standard—and the diseases associated with the parameters evaluated (in accordance with the literature review) are presented. The results show that there is a possible relationship between some of the water quality parameters and cases of gastrointestinal diseases in the area; however, more in-depth research and statistics at the national level are needed on the health of the population.
A Device for Controlling the Chlorination in Small Umbrian Water Distribution Systems
Authors: Casinini Francesco , Ferrante Marco
Published: September 2024

Umbria is an Italian region characterized by a highly fragmented water supply and distribution system, with many small systems fed by local sources. Chlorination in these small systems faces several challenges, including strong fluctuating demand, low economic significance, and limited access to infrastructure. Due to Italian regulations, the resulting frequent noncompliance with water quality standards negatively impacts performance indicators and tariffs. This research explores the possibility of implementing a low-cost chlorination system designed to adapt to varying environmental conditions (e.g., water and environmental temperature fluctuations, changes in pH, etc.) and demands. A prototype of the device was developed and tested in the Water Engineering Laboratory of the University of Perugia, Italy, to assess its ability to apply a programmable chlorination model. The effects of electronic environmental noise, along with the reliability of water meters, thermometer measurements, dosing pump control, local logging, and remote data transmission, were tested under different conditions. The results demonstrated the instrument’s readiness for field applications in pilot studies under real-world conditions.
Sustainable Groundwater Management Using Machine Learning-Based DRASTIC Model in Rurbanizing Riverine Region: A Case Study of Kerman Province, Iran
Authors: Tavakoli Mortaza , Motlagh Zeynab Karimzadeh , Sayadi Mohammad Hossein , Ibraheem Ismael M. , Youssef Youssef M.
Published: September 2024

Groundwater salinization poses a critical threat to sustainable development in arid and semi-arid rurbanizing regions, exemplified by Kerman Province, Iran. This region experiences groundwater ecosystem degradation as a result of the rapid conversion of rural agricultural land to urban areas under chronic drought conditions. This study aims to enhance Groundwater Pollution Risk (GwPR) mapping by integrating the DRASTIC index with machine learning (ML) models, including Random Forest (RF), Boosted Regression Trees (BRT), Generalized Linear Model (GLM), Support Vector Machine (SVM), and Multivariate Adaptive Regression Splines (MARS), alongside hydrogeochemical investigations, to promote sustainable water management in Kerman Province. The RF model achieved the highest accuracy with an Area Under the Curve (AUC) of 0.995 in predicting GwPR, outperforming BRT (0.988), SVM (0.977), MARS (0.951), and GLM (0.887). The RF-based map identified new high-vulnerability zones in the northeast and northwest and showed an expanded moderate vulnerability zone, covering 48.46% of the study area. Analysis revealed exceedances of WHO standards for total hardness (TH), sodium, sulfates, chlorides, and electrical conductivity (EC) in these high-vulnerability areas, indicating contamination from mineralized aquifers and unsustainable agricultural practices. The findings underscore the RF model’s effectiveness in groundwater prediction and highlight the need for stricter monitoring and management, including regulating groundwater extraction and improving water use efficiency in riverine aquifers.
Water Inflow Forecasting Based on Visual MODFLOW and GS-SARIMA-LSTM Methods
Authors: Yang Zhao , Dong Donglin , Chen Yuqi , Wang Rong
Published: September 2024

Mine water inflow is a significant safety concern in coal mine operations. Accurately predicting the volume of mine water inflow is vital for ensuring mine safety and environmental protection. This study focused on the Laohutai mining area in Liaoning, China, to reduce the reliance on hydrogeological parameters in the mine water inflow prediction process. An integrated approach combining grid search (GS) with the Seasonal Autoregressive Integrated Moving Average (SARIMA) and Long Short-Term Memory (LSTM) model was proposed, and its results were compared with Visual MODFLOW. The grid search was used to optimize the SARIMA model, modeling the linear component of nine years of water inflow data, with the remaining six months of data used for model validation. Subsequently, the prediction residuals from the SARIMA model were input into the LSTM model to capture the nonlinear features in the data and enhance the generalization capability and stability of the LSTM model by introducing Dropout, EarlyStopping, and the Adam optimizer. This model effectively handles long-term trends and seasonal fluctuations in the data while overcoming limitations in capturing periodicity and trends in complex time series data. The results indicated that the GC-SARIMA-LSTM model performs better than the Visual MODFLOW numerical simulation software in predicting mine water inflow. Therefore, without hydrogeological parameters, the GC-SARIMA-LSTM model can serve as an effective tool for short-term prediction, advancing the application of deep learning in coal mine water inflow forecasting and providing reliable technical support for mine water hazard prevention.
Data Analysis to Evaluate the Influence of Drought on Water Quality in the Colorado River Basin
Authors: Vallese Federico Danilo , Trillini Mariano , Dunel Guerra Luciana , Pistonesi Marcelo Fabian , Pierini Jorge Omar
Published: September 2024

Droughts negatively affect basins by reducing the river streamflow and increasing ion concentrations due to lower dilution. This study examines the impact of droughts in the Colorado River basin in Argentina. For this purpose, data were collected during the period from 2015 to 2021 at eight monitoring stations containing water from the river and drainage canals. The Standardized Precipitation Index (SPI) was used to analyze droughts from 1966 to 2020, and the Mann–Kendall test was used to evaluate the precipitation trends. In addition, water quality indices for human consumption (DWQI) and livestock (LWQI) were calculated by evaluating physicochemical parameters. The results show an intensification of drought since 2007, with an SPI of −1.5 in 2008, which affected the river streamflow regime and reduced the dilution capacity in the Casa de Piedra Dam. This reduction led to the deterioration of the water quality, with DWQI values indicating that 85% of the samples were not suitable for human consumption but were suitable for livestock consumption. In the drainage canals, most of the samples were of low quality for livestock consumption. The physicochemical analyses show that although some parameters (Na+, K+, CO32− + HCO3−, and Cl−) were at acceptable levels, others (electrical conductivity, SO42−, and Ca2+) exceeded the WHO’s limits, representing risks to human and livestock health. This study provides insights into how droughts and streamflow regulation affect the water quality in semiarid basins and highlights the broader applicability to other regions that present similar challenges under climate change scenarios.
Prospects for the Spread of the Invasive Oriental River Prawn Macrobrachium nipponense: Potentials and Risks for Aquaculture in Europe
Authors: Nekrasova Oksana , Lepekha Anastasiia , Pupins Mihails , Škute Arturs , Čeirāns Andris , Theissinger Kathrin , Georges Jean-Yves , Kvach Yuriy
Published: September 2024

Climate change has amplified the threat posed by aquatic invasive species as potential disruptors of biodiversity and ecosystem functioning. Species Distribution Models (MaxEnt) based on original data and ecological variables have identified contemporary seven global centers of the oriental rivel prawn Macrobrachium nipponense distribution: the native range in East Asia, Northern, Western and Eastern Europe, the Irano-Turanian region, and North and South America. By 2050, further expansion in Europe is expected, likely due to climate change, particularly temperature changes (Bio1) and rain precipitation during the warmest quarter (Bio18). However, the species may see a range reduction in southern Europe due to lower precipitation and increased droughts related to climate change. Therefore, a northward shift in the range of the species is also predicted. In the context of global change, and especially biological invasions, this study highlights the risks of introducing aquaculture based on M. nipponense and recommends controlling such economic activities, which are associated with a high risk for native species and ecosystems. Further, long-term monitoring is needed to assess impacts and to efficiently manage M. nipponense populations that are already present in their non-native habitats, for mitigating their negative effects on native species and ecosystems worldwide.
APLIKASI BUKU SAKU HIV/AIDS BERBASIS ANDROID SEBAGAI MEDIA PROMOSI KESEHATAN REMAJA
Authors: Silaban Evi Maria Lestari , Hayati Neni Fitra , Nadira Nindy Audia , Gultom Lusiana
Published: September 2024

Berdasarkan Profil Kesehatan Indonesia tahun 2020, diketahui bahwa kasus HIV/AIDS terbanyak terjadi pada kelompok umur 20-49 tahun, yang merupakan kelompok umur produktif yang aktif secara seksual dan menggunakan NAPZA suntik. Tujuan penelitian adalah untuk menghasilkan produk buku saku digital HIV/AIDS berbasis Android sebagai media promosi kesehatan. Penelitian ini berjenis mixed-methods dengan menggunakan model Borg & Gall, yaitu model deskriptif yang terdiri dari 10 langkah pengembangan media. Sampel penelitian ini dipilih secara purposive sampling, yaitu sebagian siswa SMA N 2 Padang yang berjumlah 100 responden, sedangkan informan penelitian adalah 1 orang ahli desain (programmer) dan 1 orang pakar materi. Pengumpulan data dilakukan melalui observasi pra penelitian, angket, dan wawancara mendalam. Melalui wawancara mendalam dengan programmer dan pakar materi dikembangkan buku saku, dan dilakukan validasi kelayakan media pada siswa dengan perolehan nilai 43,69 pada aspek desain dan tampilan dan 43,84 pada aspek materi. Dapat disimpulkan media buku saku digital layak untuk digunakan dalam pemberian edukasi kesehatan
Yalın Tedarik Zinciri Üzerine Bibliyometrik Bir Analiz
Authors: Nebati Emine Elif
Published: September 2024

Tedarik zinciri yönetimi, günümüzün sürekli gelişim ve değişim içinde olan iş dünyasında her geçen gün önemini arttırmaktadır. Bu süreç, bir ürünün veya hizmetin tedarik edilmesinden üretilmesine, depolanmasından müşteriye ulaştırılmasına kadar olan aşamaları kapsar. Son yıllarda, işletmelerin bu karmaşık süreçleri daha etkin bir şekilde yönetme ihtiyacı, yalın tedarik zinciri kavramını yaygınlaştırmıştır. Yalın tedarik zinciri yöntemlerinin temel amacı, müşteri taleplerine uygun ürün ve hizmetleri verimli bir şekilde temin etmektir. Bu, işletmelerin daha hızlı tepki vermesini, stok maliyetlerini minimize etmesini ve süreç verimliliğini iyileştirmesini sağlar. Yalın tedarik zinciri ve gelişimi, işletmelerin müşteri memnuniyetini artırması, maliyetleri düşürmesi ve rekabet avantajı elde etmesi için kritik öneme sahiptir. Bu çalışma, yalın tedarik zinciri yönetimini ve alandaki çalışmaları bibliyometrik analiz ile incelemeyi amaçlamaktadır. Analiz için 120 eser, Scopus analiz ve VOSviewer programları kullanılarak detaylı bir incelemeye tabi tutulmuştur. Ortaya çıkan bulgular, yalın tedarik zinciri yönetimi literatürünün geniş bir perspektifini sunmakta ve bu alandaki önemli eğilimleri, yazar iş birliklerini, ülkeler arası iş birliklerini ve yayınlanan eserlerin türlerini analiz etmeyi hedeflemektedir. Yapılan bibliyometrik analiz, bu alandaki çalışmaların çeşitliliğini ve gelişmelerini anlamamıza katkı sağlamaktadır.
SANAT ESERLERİNDE KUŞLARIN TEPKİSEL DİLİ: SAİT FAİK, RACHEL CARSON, DAPHNE DU MAURİER VE HİTCHCOCK KIYASI
Authors: Balta Şükrü Can
Published: September 2024

Tarih boyunca çeşitli milletler tarafından insanlarla birlikte birtakım nesnelere, bitkilere ve hayvanlara özel anlamlar yüklenmiştir. Kuşlar da sözü edilen bu etkileşim sınıflandırmasına dâhildir. İnsan ve kuş arasındaki ilişki sabit bir çizgide ilerlememiştir. Dolayısıyla kuşlar, olumlu olduğu kadar olumsuz çağrışımlar da taşımaktadır. Sanat, halkın duygu ve düşünce varlığının da izini sürmektedir. Bu sebeple sanat eserlerinde, kuşların kültür ve inanç eksenindeki benzer ve göreceli temsillerine erişmek mümkündür. Sait Faik’in “Son Kuşlar” ile Daphne Du Maurier’in “Kuşlar” metninin yanında Rachel Carson’un Sessiz Bahar eserinde, kuşların somut ve simgesel etkisi oldukça baskındır. Ayrıca Du Maurier’in “Kuşlar” hikâyesinden esinlenerek edebî metni Kuşlar adıyla sinema filmine dönüştüren Alfred Hitchcock da kuşların yankı uyandırıcı işlevinden yararlanmıştır. Adı geçen metinler ve eserler, içerik ve kurgu açısından sadece kendi döneminde ilgi görmemiştir. Nitekim güncelliğini muhafaza eden iletiler, hâlen kamuoyu nezdinde tartışılmaktadır. Tepkisel sembolizm, zamana, kültüre ve inanç sistemine göre değişkenlik gösterse de ele alınan sanat ürünlerinde, birbirini tamamlayıcı vasıflar dikkat çekmektedir. Karşılaştırmalı olduğu kadar disiplinler arası bir analiz niteliği taşıyan çalışmada, geleneksel ve çağdaş yorumlar bir arada kullanılmıştır.
Far from home
Authors: Żurkiewicz Danuta
Published: September 2024

After the disappearance of the Linear Pottery culture (LBK) in the area now known as the Polish Lowlands, we observe a heterogeneous cultural situation. The Late Band Pottery culture (LBPC) and the Stroke-Ornamented Ware culture (SBK) are distinguished here. Generally, none of these communities used grog (ground potsherds, ‘chamotte’) as the main type of clay temper. However, there are exceptions to these production rules. In this article, the presented pottery materials from sites in the Polish Lowlands allow us to conclude that grog temper was important for some of these communities. An attempt to interpret the addition of fragments of other vessels to the pottery clay does not point to the technical advantages of the chamotte itself, but rather to its symbolic meaning – the use of fragments of burned vessels to produce new forms. A great deal of ethnographic data justifies this approach, which is sometimes used in archaeological interpretations. The proposed hypothesis allows us to consider an alternative concept of the origin of some post-LBK communities in the Polish Lowlands.
Preparation of magnetic films using the laser induced forward transfer technique
Authors: Nakano Masaki , Higashi Kosuke , Tahara Gakuto , Yamashita Akihiro , Yanai Takeshi , Qi Chao , Nagai Keita , Shinshi Tadahiko , Fukunaga Hirotoshi
Published: September 2024

In the study, laser induced forward transfer (LIFT) of magnetic materials such as α-Fe and Nd–Fe–B was performed to directly deposit on a substrate using a YAG laser. Usage of an optical shatter and Galvano scanner enabled us to obtain LIFT-made films with a dotted pattern. The effects of conditions of laser irradiation on the deposited films were investigated. There was a threshold energy density for obtaining α-Fe dot patterns with LIFT. Energy density of a laser beam enabled a larger size of deposited dot patterns under the same laser spot size. In LIFT-prepared α-Fe films, atmosphere during the deposition did not strongly affect the crystalline structure. On the other hand, the deterioration of coercivity and squareness in LIFT-made Nd–Fe–B films was observed under a low vacuum atmosphere of 10 Pa compared with those of LIFT-made ones in a high vacuum of 10−4 Pa. It was also confirmed that Nd–Fe–B films with a coercivity of 290 kA m−1 on paper could be deposited via the LIFT technique.
Weihnachten war doch wohl schon vorüber?. Le traduzioni della particella modale epistemica wohl nelle versioni italiane della Metamorfosi di Franz Kafka
Authors: Giri Giovanni
Published: September 2024

This paper examines, quantitatively and qualitatively, the translation strategies adopted by the authors of fifteen Italian versions of Franz Kafka’s famous short story Die Verwandlung, published between 1934 and 2024, in order to render the epistemic modal particle wohl. In a first part, the German modal particles and their minor variant in Italian are presented. The subsequent analysis of the occurrences is accompanied by a brief illustration of the epistemic modality and by contrastive and translinguistic considerations, also on a diachronic scale. The third and fourth parts of the essay summarise the results, highlighting the most relevant aspects as a starting point for possible future research.
IMPACTOS DA VIOLÊNCIA OBSTÉTRICA NA SAÚDE MENTAL DAS PUÉRPERAS DO BRASIL: UM REVISÃO DE LITERATURA.
Authors: Pereira Mell Sotero , Souza Ana Luísa Meira , Braga Gessica Ramos , Costa Michela Macedo Lima , Lima Ana Késia de Oliveira
Published: September 2024

O período da gestação é uma fase singular na vida da mulher, podendo ser vivenciado de maneiras distintas: como um momento de realização e alegria quando desejado, ou como uma experiência negativa e desconfortável quando não planejado. Historicamente, até o século XVII, o parto era uma experiência essencialmente feminina, com as parteiras possuindo o maior conhecimento sobre o processo. No entanto, a partir do século XVIII, o parto começou a ser influenciado por práticas médicas, introduzindo métodos dolorosos e perigosos, como a craniotomia, marcando o início da violência obstétrica. Esta forma de violência é definida como o tratamento abusivo ou desrespeitoso durante o parto e o período neonatal, incluindo procedimentos desnecessários, uso inadequado de medicações e comentários humilhantes dirigidos às pacientes. Além das consequências físicas, como lesões no canal de parto, a violência obstétrica pode causar sérios impactos psicológicos, incluindo transtornos mentais como o Transtorno de Estresse Pós-Traumático (TEPT) e depressão pós-parto. A pesquisa realizada, baseada em uma revisão de literatura integrativa de 16 artigos, confirma que a violência obstétrica afeta diretamente a saúde mental das puérperas. Os dados revelam que práticas desumanizantes e desrespeitosas não apenas prejudicam o bem-estar físico das mulheres, mas também deixam marcas emocionais duradouras, necessitando de uma abordagem mais humanizada e de suporte psicológico adequado para melhorar a experiência do parto e promover a saúde mental das mulheres.
NEURALGIA DO NERVO TRIGÊMEO E SEUS IMPACTOS NA ÁREA ODONTOLÓGICA
Authors: Melo Patrícia Gizeli Brassalli de Melo Brassalli de , Silva Geovana Paulino da , Almeida Kaylaine  Brasil de
Published: September 2024

A neuralgia do nervo trigêmeo (NT) está entre as síndromes álgicas mais comuns na região de face.  É uma condição neuropática reconhecida por causar episódios intensos de dor facial, ocorrendo de forma súbita e lancinante. É  considerada uma das piores dores do mundo, podendo ser classificada sob três aspectos: primária, secundária e idiopática. O nervo Trigêmeo corresponde ao quinto par de nervos cranianos, sendo formado por três ramos importantes relacionados à inervação da face, o ramo oftálmico (V1), o maxilar (V2) e o mandibular (V3). A neuralgia trigeminal pode afetar qualquer um desses ramos, sendo os ramos maxilar e mandibular comumente os mais afetados. Nesse contexto, o presente trabalho tem por objetivo, ressaltar através de uma revisão de literatura, os aspectos clínicos inerentes a neuralgia do trigêmeo e sua correlação com a área odontológica, já que por vezes, devido à sua proximidade com os dentes, a NT é confundida com problemas odontológicos. Desta forma, estas informações são ferramentas importantes para o profissional da odontologia, de forma a contribuir para o direcionamento de tratamento, evitando diagnósticos equivocados e tratamentos dentários desnecessários. Ademais, por se tratar de uma condição neuropática complexa, um tratamento  multidisciplinar se faz necessário.
O PERFIL EPIDEMIOLÓGICO DA DENGUE NO ESTADO DE GOIÁS (2019-2023)
Authors: Lopes João Bosco Oliveira , Assunção Carla Medeiros , Lima Pedro Henrique Alves de , Arruda Enzo José Mendes , Oliveira Raphael Braga de , Campos Maria Fernanda Faria
Published: September 2024

O trabalho apresenta uma análise epidemiológica da dengue no estado de Goiás entre 2019 e 2023, destacando a importância da doença na saúde pública e justificando a necessidade de medidas de controle. A metodologia inclui a coleta de dados notificados e análise de informações de vigilância epidemiológica e literatura científica.
A revisão da literatura aborda a natureza da dengue, seus sintomas e complicações, além de aspectos epidemiológicos no Brasil e Goiás. Os principais fatores de risco identificados incluem a presença do mosquito Aedes aegypti e condições ambientais favoráveis.
Os dados mostram um aumento significativo de casos notificados e confirmados, com picos durante o período chuvoso, especialmente em áreas urbanas como Goiânia. As características clínicas predominantes foram febre alta, dores musculares e, em alguns casos, dengue grave.
A sazonalidade da dengue é influenciada por fatores climáticos, e o impacto socioeconômico é significativo, afetando o sistema de saúde e a produtividade. As medidas de controle incluem vigilância epidemiológica e eliminação de criadouros, sendo essencial a conscientização da população.
Os desafios futuros incluem intensificação das ações de vigilância, capacitação das equipes de saúde e integração de ações intersetoriais. O trabalho conclui com recomendações para fortalecer a prevenção e controle da dengue em Goiás, enfatizando a importância de uma abordagem integrada entre saúde, meio ambiente e educação.
BRUXISMO EM VIGÍLIA: RELAÇÃO COM FATORES PSICOLÓGICOS E PANDEMIA
Authors: Martins Laura da Silva , Jacomini Nubya da Silva , Silveira Sarah Cristina da , Okada Tayná Correa , Zaze Cesar Aurélio
Published: September 2024

RESUMO
O presente trabalho tem como objetivo, explorar o bruxismo, focando em suas formas de manifestação, causas, relação com fatores psicológicos, impactos da pandemia de COVID-19, influências de medicações, e tratamentos disponíveis. Inicialmente, o bruxismo é definido como uma atividade involuntária dos músculos da mandíbula, que pode ocorrer durante o sono, denominado Bruxismo do sono (BS), ou em vigília, denominado Bruxismo em vigília (BV). As causas do bruxismo são multifatoriais, abrangendo aspectos neurológicos, psicológicos e exógenos. Fatores como estresse e ansiedade desempenham papéis cruciais no desenvolvimento e agravamento do bruxismo, especialmente o BV, que tem sido associado a níveis elevados de tensão emocional e neuroticismo. Durante a pandemia de COVID-19, houve um aumento significativo nos casos de bruxismo, vinculado ao aumento do estresse, isolamento social e incertezas financeiras. Além dos fatores psicológicos, o uso de certos medicamentos, como os antidepressivos, também pode aumentar o risco de bruxismo, devido ao impacto desses fármacos no sistema nervoso central. O artigo aborda tratamentos variados, desde placas miorrelaxantes e intervenções farmacológicas, até psicoterapia e técnicas de relaxamento. No entanto, há uma ênfase na necessidade de abordagens multidisciplinares e individualizadas, dado o caráter multifatorial do bruxismo. O uso de técnicas de conscientização cognitiva, também é discutido, embora suas evidências ainda sejam limitadas.
Palavras-chave: Bruxismo em Vigília; Pandemia; Estresse; Ansiedade.
Desafiando o Modelo Biologicista: Uma Reavaliação da Psiquiatria à Luz da Psicologia do Patológico
Authors: Dias Arthur Ricardo , ROZEIRA CARLOS HENRIQUE BARBOSA , Silva Marcos Fernandes da , Neves Damiana Pereira da Silva , Marques Renata Aloíde Nunes Rodrigues , Lira Giovanna Dias de , Corrêa Gezilane Zanon das Neves , Andrade Rejane de Souza Silva , Costa Neto Anna Luiza , Paixão e Silva Andresa , Modesto Monalisa Sampaio do Amaral , Vizula Claudia Maria Oliveira , Pimentel Monica Gomes Lírio , Carvalho Roggher Lima , Gomes Erica Carla Soares Martins
Published: September 2024

A verdadeira cura não está apenas em consertar o que está quebrado, mas em compreender o que dói. Este artigo tem como objetivo reavaliar o modelo biologicista da psiquiatria por meio de uma pesquisa qualitativa de revisão de literatura, destacando suas limitações e propondo uma abordagem mais fenomenológica e humanista, a Psicologia do Patológico. A partir das contribuições de autores como Eugène Minkowski, Ludwig Binswanger, Viktor von Gebsattel e Eugen Bleuler, o estudo explora a importância de integrar a vivência subjetiva do paciente na compreensão e no tratamento dos transtornos mentais. Ao contrastar a psiquiatria tradicional com essas abordagens fenomenológicas, questiona-se o predomínio de uma visão que negligencia a singularidade das experiências humanas e se propõe um paradigma mais inclusivo, que integre o biológico e o fenomenológico. Este artigo provoca uma reflexão sobre a necessidade de uma psiquiatria que considere o paciente como um ser com uma história vivida, e não apenas como um corpo a ser corrigido. Além disso, discute-se o impacto da medicalização da vida e a relevância de novas classificações diagnósticas, como o RDoC e o HiTOP, que trazem uma visão mais personalizada e contínua dos transtornos mentais. A relevância do tema está na urgência de superar o reducionismo biológico, promovendo tratamentos mais completos e humanizados.
Transformações no manejo da estenose aórtica: uma revisão das técnicas de substituição valvar aórtica e seus impactos clínicos e econômicos
Authors: Storti Nóbrega Telma , Dantas Ferreira dos Santos Luysa , Serpa de Figueiredo Junior Hélcio
Published: September 2024

A substituição valvar aórtica transcateter (TAVI) revolucionou o tratamento da estenose aórtica severa, oferecendo uma alternativa minimamente invasiva à cirurgia tradicional (SAVR). O objetivo dessa revisão foi analisar os principais benefícios da TAVI em relação a SAVR no manejo da estenose aórtica e seus impactos clínicos e econômicos. Foi realizada uma busca por artigos clínicos na plataforma Pubmed e um total de 15 artigos científicos foram incluídos após a aplicação de critérios de inclusão e exclusão. Através dos estudos analisados foi observado que a comparação da TAVI com SAVR mostrou resultados semelhantes quanto a mortalidade e complicações, no entanto a TAVI apresenta custos iniciais maiores devido aos altos valores das próteses valvares. Outro ponto analisado foi a crescente expansão de indicações clínicas a TAVI e a necessidade de constantes estudos para avaliação da durabilidade das próteses. Em conclusão, a escolha entre TAVI e SAVR deve ser feita com base em uma avaliação individualizada, levando em conta fatores como idade e comorbidades.
The NSA Domestic Surveillance Program: An Analysis of Congressional Oversight During an Era of One-Party Rule
Authors: Sugiyama Tara , Perry Marisa
Published: September 2024

On December 16, 2005, the New York Times sounded a fire alarm when it revealed that, in response to the September 11, 2001 attacks, President George W Bush had issued a secret executive order permitting the National Security Agency (NSA) to conduct warrantless surveillance on individuals to unearth nascent terrorist activity. Congress responded to the disclosure of the NSA domestic surveillance program largely by shirking its oversight duties. This Note argues that when a single party controls both the executive and the legislative branches, the fire-alarm model fails to provide sufficient congressional oversight. Short of future elections altering the balance of power this Note argues that Congress should seek new methods that readily engage bipartisan support and judicial review to oversee secret executive programs more effectively.
El callejón limeño y su manifestación en zonas urbanas de Cusco-Perú
Authors:   Universidad Andina del Cusco y Universidad Nacional de San Antonio Abad del Cusco, Salas Velásquez Víctor Manuel
Published: September 2024

El objetivo del presente estudio es determinar la manifestación de las características del callejón limeño en las zonas urbanas consolidadas del Cusco en el periodo 2010-2020, a través de una investigación cualitativa que usa el método de análisis interpretativo, con una población de veinte unidades de análisis seleccionadas por relevancia y significado producto de la exploración con el uso de una ficha de registro en las zonas urbanas consolidadas de la ciudad. Los resultados muestran que el callejón surge como un modelo de vivienda colectiva cuando se subdivide un predio matriz en sub lotes y un pasillo estrecho de uso común. Su manifestación es mayor en los predios ubicados cerca al centro histórico de Cusco y la parte antigua del distrito de Wanchaq y cuanto más alejado se halle de estas zonas urbanas consolidadas, su manifestación disminuye. El callejón alberga muchas unidades de vivienda en edificaciones que varían entre cuatro y seis niveles con la tecnología tradicional de concreto armado para satisfacer la necesidad habitacional de un sector de la población de nivel socioeconómico medio, que busca generar mayores ingresos a través de la renta, pero al costo de generar viviendas que no consideran las condiciones mínimas de habitabilidad en asoleamiento, iluminación, ventilación y privacidad para sus ocupantes.
Machine Learning-Driven RUL Prediction and Uncertainty Quantification for Ball Screw Drives in a Cloud-Ready Maintenance Framework
Authors: Bott Alexander , Liu Bolin , Puchta Alexander , Fleischer Juergen
Published: September 2024

In today's rapidly evolving industrial landscape, efficient predictive maintenance solutions are essential for minimizing downtime and enhancing productivity. This research introduces an adaptive cloud-based model pipeline for predicting the Remaining Useful Life (RUL) of machine components, specifically ball screws. The pipeline integrates local preprocessing, edge computing, and cloud-based adaptive model training, ensuring data privacy and reducing data transmission volumes. The system classifies wear states using various machine learning mod-els and predicts RUL through regression analysis, incorporating uncertainty quantification for robust maintenance scheduling. The experimental setup includes accelerated degradation of ball screws, with data collected via a three-dimensional accelerometer. Feature extraction and data augmentation techniques are employed to enhance prediction accuracy. Random Forest and Gradient Boosting models demonstrate superior performance, with Random Forest selected for its robustness and uncertainty quantification capabilities. Empirical results indicate high prediction accuracy, with Random Forest achieving up to 91% accuracy in Phase 2. This cloud-ready predictive maintenance framework leverages scalable cloud infrastructure for efficient data processing and real-time updates, offering a practical solution for industrial applications. The proposed approach significantly advances the adoption of digital business models within the manufacturing industry, providing a reliable and efficient tool for predictive maintenance.