bluuebunny/crossref_metadata_2025 huggingface dataset:
Chronic Disease Management in Primary Care Setting
Authors: Abada Amir , Altalafha Samir Ibrahim
Published: March 2023

There is a correlation between advancing age and an increased risk of developing chronic diseases. Chronic diseases are those that last for an extended period of time and have an ongoing requirement for care and treatment. The primary purpose of this research project was to conduct a literature evaluation on the topic of the management of chronic diseases in primary care settings. The findings of this analysis revealed that researchers from all around the world have been actively participating in research activities to develop models that assist in the management of chronic diseases. The chronic care model is one of the more well-known models available today. In primary care, applying this strategy to the treatment of chronic diseases can bring about a reduction in both the incidence and severity of those diseases. When viewed as a whole, chronic diseases present a significant obstacle for the field of contemporary medicine and necessitate the collaboration of many different parts of the community in order to be conquered.
Recent Trends in Developing Whey Products by Advanced Technologies
Authors: Arab Safa Ansari , Kaemipoor Mahnaz , Alkhaleel Raneem , Mahdian Aref
Published: March 2023

Whey as a by-product of cheese has been considered a waste product and looked upon seriously by environmentalists and technologists. However, nowadays, it has been unlocked by modern processing technology, enabling them to recover economically in their natural state to produce new whey products with diverse functional properties which can be substituted with expensive ingredients such as egg white and milk proteins. Whey products have many nutritional, biological, and functional properties that make them excellent ingredients in a wide variety of food applications such as bakery products, beverages, dry mixes, infant formula, frozen desserts and ice cream, nutrition bars, dairy goods, nutritional supplements, and lactose-free products that reduce carbohydrate, fat, and calorie content, all of which are extensively covered in detail in this study.
Mental Health and Substance Abuse Treatment in Primary Care
Authors: Altalafha Samir Ibrahim , Abada Amir
Published: March 2023

Misuse of psychoactive chemicals and, more generally, issues related to mental health are major concerns in terms of public health around the world. It is not unusual for people to deal with both difficulties of mental health and substance addiction at the same time. The combined impacts of these disorders, both on the individuals who are affected and on society as a whole, can have a significant detrimental effect. To perform a literature review on the most recent advances affecting the key topics of this study was the objective of the current study, which aimed to answer the questions posed by the study. Using the principal research engines allowed for the collection of resources that were scientifically pertinent and related. The results of this investigation shed light on the magnitude of the problem as well as the damaging effects it has on people's lives and the communities in which they live. Both the myriad treatment choices that are available in primary care settings and the role that treating physicians play were topics of discussion during this event. When utilized in conjunction with one another, integrated therapy, evidence-based therapies such as SBIRT and CCM, as well as greater training and resources for primary care physicians, are all critical components of this strategy.
Etiological and Evolutionary Profile of Anemia in Outpatients at the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes
Authors: Drissa Sangaré , M. Cissé Sekou , Youssouf Guindo , A Diawara , Niagalé Diakité , B Berthé Brehima , Kaly Keita , Djenebou Traore , Diallo Issa , S Kaya Assetou
Published: March 2023

Introduction: Anemia is one of the most common public health problems in the world and affects all ages. Objective: To describe the etiologycal and evolutionary profile of anemia in the internal medicine unit of the Fousseyni Daou hospital in Kayes. Methodology: It was a descriptive and cross-sectional study with retrospective data collection which took place from January 1 to December 31, 2020 at the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes. It covered all anemic patients seen in outpatient clinics during the study period. Results: We identified 197 cases of anemia out of 1883 patients admitted to the Unit, either a hospital prevalence of 10.46%. The age group from 26 to 35 years was the most represented, that is to say 67 cases (34.01%) with an average age of 25 years, the female sex predominated, 107 cases (54.31%) with a sex ratio of 0.84. Housewives represented 104 cases (52.8%). The majority of patients resided in rural areas 48 cases (52.75%). Gastropathy was the most found antecedent 76 cases (38.58%) followed by hypertension 53 cases (26.90%); 121 patients (61.42%) had no history. The main clinical manifestations were: conjunctival pallor 118 cases (59.9%), vertigo 112 cases (56.85%), physical asthenia 109 cases (55.33%), dyspnea 101 cases (51.26 %), headaches 99 cases (50.25%). The associated pathologies were: hypertension 76 cases (38.58%), followed by malnutrition (anorexia) 67 cases (34.01%). Biologically, microcytic anemia was the most frequent 127 cases (64.47%), followed by normocytic anemia 53 cases (26.90%) and macrocytic anemia 17 cases (8.63%). Normochromic anemia was more encountered in 104 cases (52,79%) compared to anemia hypochromic 93 cases (47.21%). Mild anemia was more frequent 119 cases (60.41%) followed by moderate anemia 62 cases (31.47%). Anemia was severe in 16 cases (8.12%). The main etiologies of anemia were iron deficiency 98 cases (49.75%) followed by infections (anemia of inflammatory origin) with ..........
Adult-Onset Renal Cell Carcinoma Associated with Xp11.2 Translocation/TFE3 Gene Fusion: 2 Case Reports and Review of Literature
Authors: Hussein Abdallah , Hamza Abidi , Mohmad Bakouch , Imad Boualaoui , Hachem Ibrahimi Ahmed Al Sayegh , Yassine Nouini
Published: March 2023

Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, it represents 90-95% of neoplasms arising from the kidney. The Xp11.2 RCC translocation is a subtype of RCC that is defined by different translocations involving the Xp11.2 chromosome, all of which result in transcription factor E3 (TFE3) gene fusions. We presented 2 adult cases of Xp11-RCC, one patient had lymph node metastases and the second patient also had liver metastases. Both patients improved with surgical treatment by radical total nephrectomy with lymph node dissection, in addition to neoadjuvant medical treatment.
Urinary Bladder Tuberculosis – A Case Report
Authors: M Dr. Natraj, , S Dr. Vignesh, , Parveen Dr. Nisha , Khan Dr. Bushra
Published: March 2023

Introduction: Genitourinary tuberculosis (GUTB) has varied presentation and affects many organs including urinary bladder. Urinary bladder involvement without the involvement of kidneys is considered rare. Delayed diagnosis causes severe complication including thimble bladder. Here we present case report of 45 year old female patient diagnosed with tuberculous cystitis.
Paracentral Acute Middle Maculopathy in a Patient with Cilioretinal Artery Occlusion
Authors: Makino Shinji
Published: March 2023

Introduction: A 49-year-old woman presented at Inoda Eye Clinic with inferior visual field defect in the left eye. Ophthalmoscopic examination revealed well-demarcated retinal edema of the superior region at the posterior pole in the left eye. The area of retinal edema was consistent with the area of the cilioretinal artery, and therefore, cilioretinal artery occlusion was suspected. Optical coherence tomography showed hyperreflective bandlike lesions involving the middle layers of the retina at the level of the inner nuclear layer. Optical coherence tomography angiography showed decreased flow sign in outer retina layer and choriocapillaris layer rather than in superficial layer. Based on these findings, the patient was diagnosed with paracentral acute middle maculopathy due to cilioretinal artery occlusion. Optical coherence tomography angiography is a useful diagnostic examination instead of fluorescein angiography for evaluation of cilioretinal artery occlusion.
Aortic Bicuspidity and Chronic Constrictive Pericarditis: New Association
Authors: Meriem El Mousaid , Dounia Bennani , Ibrahim Nassour , Asmaa Bouazizi , Abdenasser Drighil , Leila Azzouzi , Rachida Habbal
Published: March 2023

Introduction: We report the observation of a patient hospitalized in cardiology for exploration of dyspnea associated with a picture of right heart failure for which a chronic constrictive pericarditis is evoked in front of pericardial calcifications at the trans-thoracic echography with aortic bicuspidia. This didactic observation is the occasion to recall the different complementary examinations allowing to affirm the constriction and thus to eliminate a restrictive cardiopathy.
Comparative Study of the Structure Diameter of the Species Diospyros Crassiflora Hiern (Ebenaceae) in the Permanent Structures of the Yoko Forest Reserve and the Biaro Forest (Ubundu, DR Congo)
Authors: C Lomba, B. , J Lisingo, , P Bonginda, , L Ndjele, M. B.
Published: March 2023

A study on the diametrical structure of the species Diospyros crassiflora was carried out in the Yoko Forest Reserve and in the Biaro Forest in two permanent devices of 400 ha each. This work pursued the objectives based on the distribution of the density by diameter class and the soil parameters in the two sites. All feet at dbh10 cm of the species studied were inventoried, measured across 40 strips of 10 ha each and soil samples were also taken at the two sites. 519 feet were counted, of which 325 were inventoried in the Yoko Forest Reserve. This one presents a good reconstruction of the stems of the species to have several individuals in the lower diameter classes. Soil analyzes were carried out and showed acidic soils at both sites.
Gestão de riscos como melhoria para a aquisição e distribuição de insulinas pelo SUS
Authors: De Alencar Caldas Bezerra Déa Regina , Beloti Barreto Benilson
Published: March 2023

Objetivo:  identificar a melhoria por meio da gestão de risco aplicada aos processos de aquisição e distribuição de insulinas humanas NPH. Método: O estudo foi realizado por etapas: em 1º momento foram realizadas reuniões (Brainstorming) e em 2º momento foi elaborado um formulário eletrônico em forma de questionário sendo mostrado os “eventos” de riscos com os pesos inerentes à probabilidade e ao impacto que geraram o risco inerente aos processos de aquisição e distribuição de insulinas humanas NPH e Regular pelo Ministério da Saúde. Resultados: Considerando os processos houve maior incidência de riscos médios. Não foi apontado risco muito baixo, não foi identificado risco extremo e foram apresentados apenas 02 (dois) riscos altos. Conclusão: A gestão de risco do referido estudo é uma ferramenta de melhoria para os processos de aquisição e distribuição de insulinas humanas NPH e Regular pelo Ministério da Saúde.
Uso de métodos contraceptivos durante a pandemia da COVID-19
Authors: Cerato Bispo Ana Clara , Peres Peruchi Gabriela , Tirolla Rafaele Maria , Colmiran Priscila Alexandra , Cruciol Joice Mara , Okamoto Dalla Costa Ester Massae
Published: March 2023

Objetivo: Análise do uso de métodos contraceptivos no período da pandemia. Método: Trata-se de um estudo transversal, descritivo, exploratório, aprovado pelo Comitê de Ética em Pesquisa envolvendo Seres Humanos (número 3.146.657). Foram entrevistadas via chamada telefônicas colaboradoras que retiraram contraceptivos em 01/01/2020 à 30/07/2020, excluídas os menores de 18 anos de idade; cadastro incompleto e residência fora da área de abrangência da Unidade Básica de Saúde Aquiles Stenghel (Londrina – Paraná). Resultados: Elaboraram-se tabelas descritivas com as respostas obtidas. Notou-se que quatro colaboradoras não usavam nenhum contraceptivo no momento da entrevista, e oito haviam trocado de métodos contraceptivos. Todas referiram conhecer pelo menos um contraceptivo e tê-lo utilizado em algum momento. Conclusão: O anticoncepcional injetável, apesar dos efeitos indesejáveis mencionados, continuou sendo o mais usado por entre a maioria delas, e observou-se um desuso da camisinha. Ficou evidente a necessidade de ampliar o olhar para as especificidades das mulheres, em especial as que estão em contexto de vulnerabilidades.
Doença de chagas aguda: Um relato de experiência no município de crateús
Authors: Cavalcante de Lima Carlos Alberto , Cavalcante Mota Anne Lívia , De Sousa Melo Francisca Mayra , Pontes Melo Resende Mara Mílvia , Rodrigues de Sousa Adriana , Batista Luciano Luciana , De Paula Melo Francisca Nellie , Dos Santos Oliveira Cunha Maria da Conceição
Published: March 2023

Objective: To report the experience of analyzing the epidemiological profile of patients with Acute Chagas disease in the municipality of Crateús-Ceará. Method: This is an experience report. The technical visit to the health department was in September 2022. The compulsory notification form of the patient diagnosed with Acute Chagas Disease was analyzed. Results: The epidemiological profile of the patient diagnosed with Acute Chagas Disease was identified, being: male, 42 years old, born in the rural area of Crateús - Ceará, unknown race, agricultural worker, arrived at the health unit with suspicions of acute symptoms of Chagas disease according to the notification form of injuries, made on August 02, 2022. Conclusion: Acute Chagas disease is considered a neglected disease, since it demonstrates human poverty, presenting a high morbidity and mortality rate in the endemic region.
Diagnóstico diferencial entre COVID-19 e Dengue: Estudo realizado na diretoria de vigilância epidemiológica de itajaí
Authors: Lamim Pereira Karoline Noemia , Negri Reiser Milene
Published: March 2023

Objective: To present and discuss dengue cases in the city of Itajaí-SC through a study carried out by the Epidemiological Surveillance Board of the Municipal Health Department. Method:  This is a cross-sectional observational study with a quantitative analytical approach with data collected in the year 2021, between April and July. Data analysis was performed through investigations of Covid-19 and electronic medical records of patients. Results: The data collected obtained 119 investigations and the research subjects were patients suspected of Covid-19 who had negative results for the disease, with symptoms suggestive of dengue. The sample consisted of 44 participants, where categories related to gender, neighborhood of residence and age group were identified and analyzed. Conclusion: It is believed that these findings may be extremely relevant for managers and health professionals, thus contributing to the differential diagnosis of the disease.
Game Edukasi Unsur dan Sifat Segi Empat Berbasis Android Menggunakan Unity 3D (Studi Kasus MTS Hasyimiyah Kalisidi)
Authors: Yusuf Ahmad , Mustagfirin Mustagfirin
Published: March 2023

Salah satu permasalahan pembelajaran matematika yaitu anggapan siswa tentang pelajaran matematika yang menakutkan dan kurang menarik dalam kegiatan pembelajarannya sehingga mempengaruhi hasil belajar siswa. Salah satu upaya untuk mengatasi hal tersebut adalah penggunaan media pembelajaran yang menarik. Dalam penelitian ini, digunakan game edukasi matematika dengan memanfaatkan teknologi smartphone android sebagai sebagai media pembelajaran. Permasalahan utama yang diangkat dalam penelitian ini adalah (1) Bagaimana membuat game edukasi unsur dan sifat segi empat berbasis android? (2) Bagaimana hasil penerapan pada perangkat sebagai simulasi game edukasi unsur dan sifat segi empat berbasis android?. Dari permasalahan tersebut mendorong penulis untuk melakukan penelitian dengan membuat game edukasi unsur dan sifat segi empat berbasis android menggunakan unity 3D dengan menggunakan metode pengembangan aplikasi multimedia yang terdiri dari konsep, perancangan, pengumpulan bahan, pembuatan, pengujian dan distribusi. Pembuatan aplikasi menggunakan unity 3D, hasil dari penelitian ini adalah dihasilkannya game edukasi unsur dan sifat segi empat berbasis android menggunakan unity 3D sebagai media pembelajaran variatif yang dapat mebantu guru dalam mengajar.
БИОНИЧЕСКИЙ БАНКИНГ В УСЛОВИЯХ ЦИФРОВОЙ ТРАНСФОРМАЦИИ И ЭВОЛЮЦИИ ФИНТЕХА
Authors: Таштамиров М.Р.
Published: March 2023

Совершенствование инновационного процесса обеспечивает конкурентное преимущество в банковской сфере, как того требуют сегодняшние условия экономической неопределенности. Сочетание человека и автоматизации помогает сделать организации быстрее и эффективнее конкурентов, создавая тем самым основу для конкурентоспособности и будущего коммерческого успеха. В этом контексте передача и применение бионической трансформации является подходящим подходом для решения этих задач. В статье рассмотрена концепция бионики, применительно к банковской деятельности в современных условиях активного развития и распространения цифровых финансовых технологий. Проанализированы эволюционные волны развития финтеха в мировой экономике и спрогнозированы последствия для традиционного банкинга от масштабирования цифровизации на общество и экономику.
РАЗВИТИЕ СТРАТЕГИЧЕСКОГО ПЛАНИРОВАНИЯ ВНЕШНЕЭКОНОМИЧЕСКОЙ ДЕЯТЕЛЬНОСТИ ПРЕДПРИЯТИЯ
Authors: Мержо М.Ш. , Янгульбаева Л.Ш.
Published: March 2023

Статья посвящена исследованию современных особенностей стратегического планирования внешнеэкономической деятельности предприятий и государства в целом, которые учитывают нестабильную внешнюю среду, ее новизну и сложность. Стратегическое планирование определено как важный элемент системы управления внешнеэкономической деятельностью предприятия. На основе анализа научных работ отечественных и зарубежных ученых представлена структура и этапы процесса стратегического планирования внешнеэкономической деятельности предприятия. Проведено исследование актуальных направлений развития мировой экономики, её ресурсного потенциала. Указаны приоритетные направления развития внешнеэкономической деятельности. Проанализировав процесс стратегического планирования внешнеэкономической деятельности, сформулированы виды управленческой деятельности. Выделены обязательные критерии стратегического планирования внешнеэкономической деятельности.
ИННОВАЦИОННЫЕ ТЕХНОЛОГИИ В ОСНОВЕ ТЕХНИЧЕСКОГО ПРОГРЕССА
Authors: Куразова Д.А.
Published: March 2023

Данная статья раскрывает проблему влияния инновационных технологий на технический прогресс предприятий. Так, с постоянно создаваемыми и внедряемыми новыми технологиями деловой мир переживает эпоху перемен, которая соперничает даже с достижениями эпохи промышленной революции. Чтобы быть в состоянии идти в ногу с этими изменениями, предприятия полагаются на конкурентные преимущества, предоставляемые им посредством эффективного стратегического анализа рынка
К ВОПРОСУ О ПОЛИТИЧЕСКИХ ЦЕЛЯХ ЦАРИЗМА В РАССЕЛЕНИИ ЧЕЧЕНЦЕВ ПО ТЕРЕКУ В ХVIII–НАЧ. ХIХ ВЕКОВ
Authors: Гелаева З.А.
Published: March 2023

В статье исследуется проблема расселения чеченцев по Тереку, как один из методов мирного завоевания края в XVIII веке, политические цели, которые преследовала царская Россия, поощряя это расселение.
МЕРЫ ПРОФИЛАКТИКИ МОЛОДЕЖНОГО ЭКСТРЕМИЗМА ОРГАНАМИ ГОСУДАРСТВЕННОЙ ВЛАСТИ И МЕСТНОГО САМОУПРАВЛЕНИЯ
Authors: Ахъядов Э.С.-М. , Хаджиев У.К.
Published: March 2023

Данная статья направлена на всесторонний социально-правовой анализ проблем противодействия и профилактики молодежного экстремизма в современных российских реалиях. В статье рассматриваются предпосылки и факторы молодежного экстремизма, проблемные аспекты эффективности противодействия данному явлению. Автором приводится широкий перечень применяемых мер, а также новых предложений, направленных на комплексную профилактику экстремизма в молодежной среде.
ИНФОРМАЦИОННАЯ БЕЗОПАСНОСТЬ ДЕТЕЙ И ПОДРОСТКОВ
Authors: Габазов Т.С.
Published: March 2023

В современном технологическом мире Интернет имеет важное значение, привлекая большее внимание, чем другие средства массовой информации. Дети и подростки являются активными пользователями новых технологий, и поэтому проблема неконтролируемой детской активности в Интернете является одной из важнейших в современном мире. Дети убеждены, что знают о цифровом мире все и зачастую ведут себя в Интернете бесконтрольно, думая о вседозволенности и безнаказанности своих действий. Но становится страшно, когда жертвами этой безнаказанности становятся сами дети. Цель исследования - построение гипотезы эффективной модели правового регулирования доступа и потребления информационных продуктов, максимально безопасных для психического, физического развития и здоровья детей, а также их социализации с учетом международных стандартов. Для достижения цели используется общенаучный диалектический метод познания.
ПРАВОНАРУШЕНИЯ В СЕТИ ИНТЕРНЕТ: НАРУШЕНИЯ ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ
Authors: Магомадова Э.И.
Published: March 2023

В статье рассмотрена проблема одного из современных видов правонарушения в сети Интернет: нарушение интеллектуальной собственности. Также рассмотрена современная интерпретация понятия «интеллектуальная собственность», его роль и значение, а также вопрос охраны интеллектуальной собственности.
АТТЕСТАЦИЯ РАБОТНИКОВ ПО СЛУЖЕБНОМУ И ТРУДОВОМУ ПРАВУ: ЗНАЧЕНИЕ И СРАВНИТЕЛЬНЫЙ АНАЛИЗ
Authors: Муцалов Ш.Ш. , Дадаев Х.М.
Published: March 2023

В современных условиях в стране происходят существенные изменения, связанные с реформированием институтов государственной службы. Существенные перемены произошли во внутригосударственном образовании посредством административной реформы и реформы в секторе госслужбы, которые в конечном счете и предопределяют несколько иной подход в трактовании и понимании такого понятия, как аттестация. Автором выявлены характерные для аттестации гражданских госслужащих черты, позволяющие разграничить институты в секторе государственного управления и трудовом праве. Стоит отметить, что принципы проведения аттестации и в трудовом, и в служебном праве имеют доктринальный характер и основаны на общих свободах и правах человека. Однако в результате краткого сравнительного анализа процедуры аттестации в служебном и трудовом праве выявлены характерные для аттестации гражданских госслужащих черты, позволяющие разграничить институты аттестации в служебном и трудовом праве. Но отсутствие легального определения принципов проведения аттестаций без учета специальных норм о критериях оценки профессионализма или компетентности сотрудника позволяет задуматься над тем, являются ли нормы служебного права об аттестации такими уж специальными.
Informal Professional Communication of Rehabilitation Specialists and its Significance for their Practical Activities
Authors: Brych Valeriya , Dub Mariana M.
Published: March 2023

Aim: To investigate the scope, forms and activeness of informal professional communication of rehabilitation specialists using information and communication channels and its significance for their practical activities.
Materials and Methods: The following methods were used during the research: sociological; statistical; structural and logical analysis; generalization. Copies of the author’s original sociological survey questionnaire were used as research materials.
Results: The analysis of the results of survey revealed that absolutely all interviewed rehabilitation specialists consider it useful to create virtual groups for professional communication with colleagues in the field of rehabilitation through modern information and communication channels. 44.9±3.7% of respondents recognized themselves as passive participants of such groups. But 98.9±0.8% of the survey participants consider the information received in such communication groups to be useful for professional clinical activities in the field of rehabilitation. It was determined that the issues of correct preparation of documentation when providing services under the packages of the National Health Service of Ukraine (78.7±3.1%) and the problems of organizing the provision of rehabilitation services in health care facilities (74.2±3,3) were discussed most often in the groups.
Conclusions: The development of virtual professional communities of rehabilitation specialists helps them to exchange information and improve their knowledge in matters of organizing the provision of rehabilitation services in health care institutions and processing documentation. Provided that the facilitation of communication topics of professional groups is established, it is possible to improve their functioning and attract more specialists to active participation.
A Comparative Study on Mortality of Trauma – Our Experience in Peshawar
Authors: Ahmed Ijaz , Baig Zahid Farooq , Farukh Aamir , Qazi Umberin Koukab , Safdar Maria , Tareen Tariq Bashir
Published: March 2023

Objective: To compare the mortality among different modes of trauma and different areas/parts of the bodyinvolved by trauma.Study Design: Comparative descriptive study.Place and Duration of Study: This study was carried out in the Department of Critical Care Medicine, Combined Military Hospital (CMH) Peshawar, from October 2015 to September 2017.Materials and Methods: All the patients with trauma admitted to in the Intensive Care Unit (ITC) of CMHPeshawar were included in this study. All the data including their cause of injury and the areas involved werecollected on computerized forms using Microsoft Access 2007 and patients were followed till their death ordischarge from ITC. The data collection was prospective and cross-sectional.Results: During the study period a total of 448 trauma patients were admitted in the ITC of CMH Peshawar.Males (93.3 %) outnumbered females (6.7%) by almost 14:1. Mean age of patients was 31 ± 13.4 years (range1.5 to 88 years). The mean ITC stay of patients was 6.8 ± 6.5 days. Out of these 448 patients, 394 (87.9%)survived and were shifted from ITC to lower levels of care. The survival ratio was slightly higher in femalescompared to males with a p-value of 0.348. Patients who survived were relatively younger (30 years+ 13) thanthe patients who expired (37 years+ 15) with a p-value of 0.071. The trauma patients who survived stayed oneday longer (7 days) than the patients who expired (6 days), p-value 0.057. Depending upon the cause of trauma,the highest mortality was seen in patients of burns (40%) followed by RTA (17.2%) and GSW (10.6) P-value0.011. Similarly depending onthe area of the body involved highest mortality is seen in patients with burns(40%), followed by polytrauma (16.7%) and head injury (16.1%).Conclusion: Trauma is a problem of young adults which can lead to disabilities and loss of life years in its victims. RTA is the commonest cause of trauma with a high fatality rate. Depending on body area involvementpolytrauma and head injury due to any cause are common and carry a high mortality. Burns are the lesscommon but the deadliest cause of trauma.
Fear – Shifting from the Virus to the Vaccine
Authors: Naeem Afnan , Usman Javaid , Furqan Warda
Published: March 2023

Objective: To determine the reasons for hesitancy against the COVID-19 vaccine in the Rawalpindi/Islamabadregion of Pakistan.Study Design: Cross-sectional study.Place and Duration of Study: The study was conducted at the Department of Microbiology, Army MedicalCollege, Rawalpindi, Pakistan, from 1 June 2021 to 1 July 2021.Materials and Methods: A questionnaire of socio-demographic variables and factors leading to vaccinationhesitancy was administered to the participants after obtaining informed consent. Data were analyzed by usingSPSS version 27.0.Results: Out of total of 1067 participants, 41 % declined vaccination. The main reason for refusal of the vaccinewas fear of death 25.6% followed by fear of infertility 16.5%. Social media also played a major role in leading tovaccine hesitancy as 46.3 % of the study population expressed distrust in vaccines because of social mediainfluence, followed by 44.5% having concerns about the safety and efficacy of vaccines.Conclusion: The vaccine acceptance rate was sub-optimal among participants. As almost 41 % of theparticipants were hesitant. The success of any vaccination program largely depends on the public willingness toaccept the vaccine therefore policy makers and stake holders should try to address the apprehensions of thegeneral public.
Rotavirus Samples processing using Indigenously Developed Molecular Transport Medium (IMTM)
Authors: Un Nisa Tayyab , Babar Muhammad Mujtaba , Ali Ashaq , Zafar Urooj , Ahmad Aqeel , Khan Saifullah
Published: March 2023

Objective: To perform comparative diagnostic study with rotavirus infected stool samples for efficacy ofindigenously prepared molecular transport medium (IMTM).Study Design: It was an experimental study.Place and Duration of Study: The study was conducted at Department of Microbiology of University of Karachi,Karachi Pakistan from June to July 2021.Materials and Methods: The current study was conducted based on hospital based surveillance of rotavirusgastroenteritis among children <5 years of age, stool samples were collected in commercially available viraltransport medium. Samples were known rotavirus positive /negative through PREMIER Rota clone Enzyme-Linked Immunosorbent Assay (ELISA) kit diagnostic test. Total 64 stool samples were selected to evaluate theefficacy of indigenous molecular transport medium (IMTM). Stool samples were spiked in IMTM andcommercial available viral transport medium (CVTM). RNA extraction and Real-time PCR were performed byQIAmp and in house assay respectively as per manufacturer' instructions. Similar method of RNA extractionand Real-Time PCR for both type of spiked samples was adopted.Results: Comparative analysis of Cycle threshold (Ct) values of paired samples (IMTM vs CVTM) was performed.Real-Time (RT-PCR) for rotavirus positive and negative results were consistent with each pair (p<0.0001).Conclusion: The indigenously formulated IMTM found capable for stool sample collection, transportation andprocessing for rotavirus detection through Real-time PCR.
Immunotherapy in Lung Cancer: A Narrative Literature Review
Authors: Citra Wahyudin Hendris Utama , Afriani Afriani  , Fenty Anggrainy  , Sabrina Ermayanti
Published: March 2023

Lung cancer is the most common cause of death from cancer in both men and women worldwide. Cancers with low immunogenicity often do not present antigens, so immune responses can be avoided. Uncontrolled growth of tumor cells occurs due to various factors such as activation of immunosuppressive mechanisms, induction of various immunosuppressive cells, and expression of immune checkpoint molecules. The development of lung cancer management has progressed since the discovery of molecular-based target therapy and immunotherapy. The high expression of tumor mutational burden in lung cancer indicates high immunogenicity in lung cancer. Various immunological mechanisms involving programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) have been developed for the treatment of lung cancer by utilizing immune system modulation. Nivolumab is the first approved immunotherapy for lung cancer, followed by pembrolizumab, atezolizumab, and durvalumab. The use of immunotherapy involving immune checkpoint inhibitors is an important breakthrough in the management of cancer, including lung cancer. This literature review aimed to describe immunotherapy in lung cancer that focuses on immune checkpoint inhibitors anti-PD-1 and anti-PD-L1.
STRATEGI DIGITAL MARKETING UNTUK PEMBERDAYAAN UMKM DI INDONESIA
Authors: Maszudi Edi
Published: March 2023

ABSTRACT The purpose of this research is to find out digital marketing strategies for empowering MSMEs in Indonesia 2021-2022. Type of data used; secondary and tertiary data. This research method: qualitative data analysis. The problem in this research: what is the digital marketing strategy for empowering MSMEs in the digital era in Indonesia? The digital marketing strategy for Indonesian MSMEs in 2021, 2022 is carried out with five strategies. First, the quality of products from MSMEs must follow the SNI (Indonesian National Standard). Second, the packaging must be attractive, healthy and unique. Third, must enter the market place and social media. Fourth, do digital branding. Fifth, give a halal label. The tough challenge is that not all MSME actors understand digital marketing. Based on data, the number of MSMEs in 2021, as many as 64 million, there are 19 million MSMEs entering the digital realm. The target of the Cooperatives and MSMEs Service is to collect as many as 14.5 million from Cooperatives, MSMEs in 2022. There are 65 million cooperatives, MSMEs in 2022. Based on data, only 19% of MSMEs have entered the digital realm. Keywords: Strategy, Digital Marketing and MSME
Ammattimainen luottamushenkilö yhdistävänä poliittisena johtajana
Authors: Parkkinen Jonne , Paananen Henna , Kyösti Anni
Published: March 2023

The professional local elected official as integrative political leader
As increasing numbers of Finnish municipalities have introduced positions for full-time and part- time elected officials, the work of local political leaders has become professionalized. This article advances the understanding of the competence needs of professional local elected officials. The empirical data consist of interviews with local elected officials. The data were analyzed using qualitative content analysis. The results indicate that the professional local elected officials tend to work as integrative political leaders. These integrative political leaders work adaptively as they aim to advance collaboration between different actors. They need, for example, communication and interaction skills, self- leadership skills, political skills, knowledge management skills, and systemic understanding to be successful in their work.
Pengaruh Model Pembelajaran Inkuiri Bebas terhadap Peningkatan Literasi Sains Sekolah Menengah Pertama
Authors: Ade Sintia Wulandari  , Ketut Suma  , Ida Bagus Putu Mardana
Published: March 2023

Penelitian ini bertujuan untuk mendeskripsikan dan menjelaskan perbedaan literasi sains siswa yang dibelajarkan menggunakan model pembelajaran inkuiri bebas dengan model pembelajaran konvensional. Penelitian ini termasuk dalam penelitian quasi eksperimental (eksperimen semu) dengan rancangan non-equivalent pretest-posttest control group design. Populasi penelitian adalah semua siswa kelas VIII SMP Negeri 4 Singaraja Tahun pelajaran 2022/2023 sebanyak 11 kelas (357 siswa), dengan sampel sebanyak 2 kelas (64 siswa) yang terbagi kedalam dua kelas. Prosedur pengambilan sampel penelitian menggunakan teknik cluster random sampling. Variabel penelitian ini adalah literasi sains siswa yang dikumpulkan menggunakan metode tes. Data literasi sains dianalisis menggunakan teknik analisis statistik deskriptif dan statistik inferensial. Statistik deskriptif digunakan untuk mendeskripsikan hasil rata-rata literasi sains siswa sedangkan statistik inferensial untuk menguji hipotesis penelitian menggunakan uji MANOVA satu jalur dengan taraf signifikansi 0,05. Berdasarkan hasil analisis, ditemukan hasil terdapat perbedaan literasi sains siswa yang dibelajarkan menggunakan model pembelajaran inkuiri bebas dengan model pembelajaran konvensional (F=645,630; p<0,05). Berdasarkan temuan tersebut dapat disimpulkan bahwa terdapat pengaruh positif sebesar 99% pada model pembelajaran inkuiri bebas terhadap peningkatan literasi sains siswa sekolah menengah pertama.
Pengembangan Media Pembelajaran Berbasis Android Menggunakan Lectora Inspire pada Materi Larutan Penyangga Kelas XI SMA
Authors: Desy Kurniawati  , Afdina Afdina
Published: March 2023

Jenis penelitian ini adalah Educational Design Research (EDR) dengan menggunakan model pengembangan plomp yang terdiri dari 3 tahap yaitu tahapan pendahuluan, prototipe dan penilaian. Pada penelitian ini penulis membatasi penelitian yang dilakukan sampai pada tahap prototipe yang menghasilkan prototipe III. Penelitian ini bertujuan untuk mengembangkan media pembelajaran interaktif berbasis android serta menentukan tingkat validitasnya dan diharapkan mampu membantu guru dalam mengatasi kendala pembuatan media pembelajaran pembelajaran khususnya pada materi larutan penyangga. Uji validitas aplikasi media pembelajaran dilakukan oleh delapan orang validator yaitu empat orang dosen kimia FMIPA, dua orang dosen FT UNP dan dua orang guru SMA Pertiwi 1 Padang. Data yang didapatkan dari validator selanjutnya dianalisis menggunakan Aiken’s V. Hasil penelitian ahli materi didapatkan nilai rata-rata Aikens’ V untuk aspek kelayakan isi, konstruk, kebahasaan dan kegrafisan berturut-turut sebesar 0,91; 0,89; 0,93 dan 0,84 dengan kategori valid dan hasil penelitian ahli media didapatkan nilai rata-rata Aiken’s v untuk aspek tampilan, pemprograman dan pemanfaatan berturut turut sebesar 0,84; 0,94; dan 0,81 dengan kategori valid. Berdasarkan hasil penelitian dapat disimpulkan bahwa media pembelajaran interaktif berbasis android menggunakan lectora inspire pada materi larutan penyangga kelas XI SMA yang dihasilkan sudah valid. Oleh karena itu penelitian ini dapat dilanjutkan ketahap uji praktikalitas dan efektifitas.
IRIS – NAPREDNI INTEGRALNI NUKLEARNI REAKTOR MODULARNE IZVEDBE
Authors: Nikola Čavlina  , Davor Grgić  , Dubravko Pevec  , Mario Carelli  , Bojan Petrović
Published: March 2023

Glavne značajke reaktora IRIS (International Reactor Innovative and Secure) date su u ovom članku. IRIS je integralni, modularni, lakovodni reaktor srednje snage (335 MWe). Projekt reaktora IRIS razvija međunarodni konzorcij od dvadesetak organizacija iz deset zemalja predvođenih kompanijom Westinghouse. Primarni cilj projekta je razviti siguran, pouzdan i ekonomičan reaktor male do srednje snage. U članku je opisana integralna reaktorska posuda koja osim jezgre reaktora, moderatora, kontrolnih šipki i reflektora neutrona sadrži parogeneratore, reaktorske pumpe, mehanizme kontrolnih šipki i tlačnik. Jedinstvene sigurnosne karakteristike (,,safety-by-design) omogućile su manje i jednostavnije pasivne sigurnosne sustave. Poboljšana sigurnost i pouzdanost, ekonomičnost, te mogućnost postupne izgradnje novih kapaciteta uz relativno male investicije čine IRIS naročito privlačnim za manje elektroenergetske sustave.
ENERGETSKI AUDIT ZGRADA JAVNE NAMJENE - OBRADA PODATAKA I PRIJEDLOG MJERA ENERGETSKE EFIKASNOSTI
Authors: Vesna Kolega
Published: March 2023

Provođenje energetskog audita zgrade je djelotvorna metoda s ciljem reduciranja potrošnje svih tipova energije u zgradama javne namjene. U ovom će članku biti detaljno opisani načini obrade podataka prikupljenih prema obrascu za energetski audit zgrada javne namjene i metode određivanja liste prioritetnih mjera energetske efikasnosti za konkretnu zgradu javne namjene.
Intra-Arterial Concurrent Chemo Radio Therapy (IACCRT) can be a Feasible Salvage Treatment for Fragile Advanced Cancer Patient to Restore Better Quality of Life
Authors: Wah Young Andrew Yau , Yen Cheng Yo , Hung Chil Hsin
Published: March 2023

Combine modality anti-cancer treatment, Concurrent Chemo-Radio Therapy (CCRT) is a recommended approach for relatively resistant tumor in clinical oncology. But it is relatively more toxic to patient, and severely disrupt patient’s quality of life due to systemic side-effects causing by intravenous cytotoxic drugs delivery, especially for those fragile advanced cancer patients. Intra-arterial infusion chemotherapy is another option for CCRT because of not only a better tumor respond documented, and also bonus a better quality of life improvement. We demonstrated an advanced buccal cancer patient who had been heavily treated, but rapidly recurrence head and neck tumor for salvage treatment with Intra-Arterial Concurrent Chemo-Radio Therapy (IACCRT). Complete tumor respond was resulted, and also restored a very satisfactory gain on quality of life, ECOG had been improved from score 3 to 1. We concluded that IACCRT is a feasible treatment choice for fragile advanced cancer patient.
TD 2854 - Transporte urbano e insuficiência de acesso a escolas no Brasil
Authors: Saraiva Marcus , Silva Luiz Pedro , Braga Carlos Kauê Vieira , Pereira Rafael H. M.
Published: March 2023

Facilitar o acesso da população mais pobre a educação e essencial para reduzir desigualdades e promover inclusão social. Estudos recentes tem explorado a dimensão espacial da desigualdade no acesso a educação. No entanto, poucos desses estudos analisam se a população teria acesso suficiente a estabelecimentos de educação nas cidades brasileiras, e como essas condições de acessibilidade variam espacialmente e afetam especificamente a população de menor renda. Este estudo apresenta a primeira analise em larga escala de acessibilidade as oportunidades de educação no ensino publico das vinte maiores cidades do Brasil em alta resolução espacial. Este trabalho foca nas condições de acesso de crianças e jovens de baixa renda as escolas de nível infantil e médio, onde se encontram os maiores desafios de universalização da educação no pais. Considerando-se a acessibilidade a pé e por transporte publico, o estudo investiga a exclusão social relacionada a educação na escala intraurbana, bem como entre cidades e regiões, ao analisar diferentes linhas de insuficiência (LIs) de acessibilidade. Os resultados indicam que ainda são necessários significativos avanços em direção a universalização do acesso a educação no Brasil, principalmente quando são consideradas as vagas publicas de ensino infantil e médio. Parte substancial das crianças de famílias mais pobres possui acessibilidade insuficiente a escolas de educação infantil e ensino médio, principalmente em áreas de baixa densidade populacional nas periferias urbanas. A baixa densidade dessas áreas cria um desafio para a implantação de escolas em numero e cobertura espacial suficientes para melhorar o acesso escolar. Os resultados do estudo contribuem para o melhor entendimento da dimensão geográfica da insuficiência de acessibilidade a educação da população mais pobre, que pode ocasionar sua exclusão das mais diversas oportunidades essenciais ao longo da vida e aprofundar níveis de pobreza e desigualdades sociais.
Cuidados en la agenda política: propuestas y brechas a partir de la campaña presidencial de 2021
Authors: Villalobos Pablo , Alliende Trinidad , Browne Jorge , Contrucci Isabel , Araya Alejandra-Ximena , Palacios Josefa
Published: March 2023

El debate sobre los cuidados de largo plazo (CLP) y la necesidad de establecer sistemas de CLP ha alcanzado un consenso mundial, con organizaciones internacionales como la Organización Mundial de la Salud (OMS) que alientan a los países a actuar al respecto. Durante las pasadas elecciones presidenciales en Chile, varios candidatos hicieron propuestas señalando la necesidad de implementar nuevas soluciones para hacer frente a las crecientes demandas de servicios de cuidados en el país. Estas propuestas —que incluyen a los CLP, pero también otras dimensiones de los cuidados— fueron novedosas en el debate político y representan un paso importante en la adopción de respuestas integrales a las necesidades de CLP en Chile. Utilizando el marco de sistemas de CLP de la OMS, este artículo analizó las propuestas realizadas durante la campaña presidencial de 2021 en Chile, identificando áreas cubiertas y brechas en las propuestas de los distintos candidatos. Los resultados muestran que en las propuestas predominan dimensiones como la gobernanza del sistema de CLP, la fuerza laboral y la prestación de servicios, con brechas importantes en cuanto a financiamiento, información y estrategias de innovación del sistema. Los hallazgos son relevantes para respaldar el esfuerzo del nuevo gobierno en la implementación de un sistema de CLP en Chile, en particular considerando que la instalación de un sistema nacional de cuidados es uno de los principales desafíos que ha decidido enfrentar el nuevo gobierno, con el anhelo de, además, iluminar las discusiones políticas de otros países sobre el desarrollo de sistemas y políticas de CLP.
We Are Not Born Submissive: How Patriarchy Shapes Women’s Lives, de Manon García
Authors: Darat Nicole
Published: March 2023

Reseña del libro We Are Not Born Submissive: How Patriarchy Shapes Women’s Lives, de Manon García. Princeton: Princeton University Press, 2021. 248 pp.
Discapacidad en adultos en Chile: menores ingresos del trabajo y mayores gastos
Authors: Vial Bernardita , Martínez Claudia
Published: March 2023

De acuerdo a la Encuesta Nacional de Discapacidad (ENDISC 2015), un 15,1% de los adultos menores de 65 años se encuentra en situación de discapacidad en Chile, con un 4,8% con discapacidad severa. La prevalencia es mayor en mujeres, aumenta con la edad y disminuye con el nivel educacional. Un 8,4% de las personas del primer quintil de ingreso se encuentra en situación de discapacidad severa, figura que cae a un 2,9% en el quintil de mayores ingresos. Al mismo tiempo, las personas con discapacidad cuentan con una menor participación laboral, menor ocupación y mayor tasa de desempleo. Al controlar por características observables de las personas asociadas al ingreso del trabajo como educación y género, entre otros, se encuentra que la situación de discapacidad está asociada a una disminución de los ingresos del trabajo de aproximadamente un 21%. Por otra parte, las personas con discapacidad tienen dos veces el nivel de gasto en servicios de salud. Por lo tanto, se encuentran en una situación desventajosa tanto por los menores ingresos como por los mayores gastos que requieren.
Max Weber and the Path from Political Economy to Economic Sociology, de Christopher Adair-Toteff
Authors: Hernández Aracena Javier
Published: March 2023

Reseña del libro Max Weber and the Path from Political Economy to Economic Sociology, de Christopher Adair-Toteff. London: Routledge, 2022. 145 pp.
Un filósofo entre los antropólogos. La formación del pensamiento de Lévi-Strauss en Brasil y Nueva York
Authors: Vergara Jorge Iván
Published: March 2023

A la luz de la reciente publicación de los escritos de Claude Lévi-Strauss (1908-2009) realizados durante su exilio en Estados Unidos, este ensayo reconstruye la formación del pensamiento del destacado antropólogo francés durante su estancia en Brasil y en Nueva York. Estos doce años (desde 1935 hasta 1947) son fundamentales en la gestación del estructuralismo, la gran escuela teórica formada por Lévi-Strauss. También significan su primera y definitiva inmersión en el trabajo de campo entre diversos pueblos indígenas (Bororo, Caduveo, Nambikwara y Tupi-Kawahib). Junto a su labor docente en la Universidad de São Paulo, sus expediciones etnográficas en el Mato Grosso le permitieron ir desarrollando ciertos temas centrales en su obra posterior, como las relaciones de parentesco, el intercambio, el arte indígena o la mitología. Al mismo tiempo, estos escritos tempranos reflejan influencias teóricas y disciplinarias diversas: la filosofía de Rousseau, la escuela sociológica francesa de Durkheim y Mauss, el marxismo, el psicoanálisis y la antropología anglosajona. Se busca analizarlos a la luz de su obra madura, intentando distinguir continuidades y rupturas. Adicionalmente, se pretende esclarecer ciertos aspectos polémicos acerca del autor, como la calidad de su trabajo etnográfico.