bluuebunny/crossref_metadata_2025 huggingface dataset:
Field assessment of a pulse width modulation (PWM) spray system applying different spray volumes: duty cycle and forward speed effects on vines spray coverage
Authors: Grella Marco , Gioelli Fabrizio , Marucco Paolo , Zwertvaegher Ingrid , Mozzanini Eric , Mylonas Nikolaos , Nuyttens David , Balsari Paolo
Published: August 2021

The pulse width modulation (PWM) spray system is the most advanced technology to obtain variable rate spray application without varying the operative sprayer parameters (e.g. spray pressure, nozzle size). According to the precision agriculture principles, PWM is the prime technology that allows to spray the required amount where needed without varying the droplet size spectra which benefits both the uniformity of spray quality and the spray drift reduction. However, some concerns related to the effect of on–off solenoid valves and the alternating on/off action of adjacent nozzles on final uneven spray coverage (SC) have arisen. Further evaluations of PWM systems used for spraying 3D crops under field conditions are welcomed. A tower-shaped airblast sprayer equipped with a PWM was tested in a vineyard. Twelve configurations, combining duty cycles (DC: 30, 50, 70, 100%) and forward speeds (FS: 4, 6, 8 km h−1), were tested. Two methodologies, namely field-standardized and real field conditions, were adopted to evaluate the effect of DC and FS on (1) SC variability (CV%) along both the sprayer travel direction and the vertical spray profile using long water sensitive papers (WSP), and (2) SC uniformity (IU, index value) within the canopy at different depths and heights, respectively. Furthermore, the SC (%) and deposit density (Nst, no stains cm−2), determined using short WSP, were used to evaluate the spray application performances taking into account the spray volumes applied. Under field-controlled conditions, the pulsing of the PWM system affects both the SC variability measured along the sprayer travel direction and along the vertical spray profile. In contrast, under real field conditions, the PWM system does not affect the uniformity of SC measured within the canopy. The relationship between SC and Nst allowed identification of the ranges of 200–250 and 300–370 l ha−1 as the most suitable spray volumes to be applied for insecticide and fungicide plant protection products, respectively.
A dual compartment cuvette system for correcting scattering in whole-cell absorbance spectroscopy of photosynthetic microorganisms
Authors: Hervey John R. D. , Bombelli Paolo , Lea-Smith David J. , Hulme Alan K. , Hulme Nathan R. , Rullay Atvinder K. , Keighley Robert , Howe Christopher J.
Published: August 2021

Absorption spectroscopy is widely used to determine absorption and transmission spectra of chromophores in solution, in addition to suspensions of particles, including micro-organisms. Light scattering, caused by photons deflected from part or all of the cells or other particles in suspension, results in distortions to the absorption spectra, lost information and poor resolution. A spectrophotometer with an integrating sphere may be used to alleviate this problem. However, these instruments are not universally available in biology laboratories, for reasons such as cost. Here, we describe a novel, rapid, and inexpensive technique that minimises the effect of light scattering when performing whole-cell spectroscopy. This method involves using a custom made dual compartment cuvette containing titanium dioxide in one chamber as a scattering agent. Measurements were conducted of a range of different photosynthetic micro-organisms of varying cell size and morphology, including cyanobacteria, eukaryotic microalgae and a purple non-sulphur bacterium. A concentration of 1 mg ml−1 titanium dioxide, using a spectrophotometer with a slit width of 5 nm, produced spectra for cyanobacteria and microalgae similar (1–4% difference) to those obtained using an integrating sphere. The spectrum > 520 nm was similar to that with an integrating sphere with the purple non-sulphur bacterium. This system produced superior results to those obtained using a recently reported method, the application of the diffusing agent, Scotch™ Magic tape, to the side of the cuvette. The protocol can be completed in an equivalent period of time to standard whole-cell absorbance spectroscopy techniques, and is, in principle, suitable for any dual-beam spectrophotometer.
Learning science through argumentative synthesis writing and deliberative dialogues: a comprehensive and effective methodology in secondary education
Authors: Casado-Ledesma Lidia , Cuevas Isabel , Martín Elena
Published: August 2021

Scientific literacy can be promoted through oral and written argumentative practice. Collaborative discourse has proven effective in fostering conceptual understanding, especially when discussions are developed under deliberative goals. Likewise, writing tasks as argumentative syntheses stand out for its epistemic value and its contribution to constructive learning processes. However, there are no known educational interventions that have combined these two didactic activities to teach science. The objective of this research was to compare the impact of four intervention programs, based on deliberative dialogues and argumentative synthesis writing activities, on the learning of socio-scientific content. The four programs resulted from the combination of two instructional components (Explicit Instruction; Guide), while deliberative dialogues and argumentative syntheses were constant elements. We conducted a pre-post quasi-experimental study in which participated 151 Spanish third grade secondary school students. Socio-scientific learning was evaluated through a content test made up of open questions. The results showed all students progressed in their socio-scientific knowledge. Instructional practices did not have a direct effect on content learning. However, we observed an indirect effect of explicit instruction on learning socio-scientific content, through learning of argumentative synthesis writing. Besides, we found a positive relation between progression in synthesis writing and knowledge acquisition.
Uncertainty modelling and computational aspects of data association
Authors: Houssineau Jeremie , Zeng Jiajie , Jasra Ajay
Published: August 2021

A novel solution to the smoothing problem for multi-object dynamical systems is proposed and evaluated. The systems of interest contain an unknown and varying number of dynamical objects that are partially observed under noisy and corrupted observations. In order to account for the lack of information about the different aspects of this type of complex system, an alternative representation of uncertainty based on possibility theory is considered. It is shown how analogues of usual concepts such as Markov chains and hidden Markov models (HMMs) can be introduced in this context. In particular, the considered statistical model for multiple dynamical objects can be formulated as a hierarchical model consisting of conditionally independent HMMs. This structure is leveraged to propose an efficient method in the context of Markov chain Monte Carlo (MCMC) by relying on an approximate solution to the corresponding filtering problem, in a similar fashion to particle MCMC. This approach is shown to outperform existing algorithms in a range of scenarios.
The knowledge norm of assertion: keep it simple
Authors: Lewis Max
Published: August 2021

The simple knowledge norm of assertion (SKNA) holds that one may (epistemically permissibly) assert thatponly if one knows thatp. Turri (Aust J Philos 89(1):37–45, 2011) and Williamson (Knowledge and its limits, Oxford University Press, Oxford, 2000) both argue that more is required for epistemically permissible assertion. In particular, they both think that the asserter must assert on the basis of her knowledge. Turri calls this the express knowledge norm of assertion (EKNA). I defend SKNA and argue against EKNA. First, I argue that EKNA faces counterexamples. Second, I argue that EKNA assumes an implausible view of permissibility on which an assertion is epistemically permissible only if it is made for a right reason, i.e., a reason that contributes to making it the case that it is epistemically permissible to make that assertion. However, the analogous view in other normative domains is both controversial and implausible. This is because it doesn’t make it possible for one to act or react rightly for the wrong reason. I suggest that proponents of EKNA have conflated requirements for φ-ing rightly (or permissibly) with requirements for φ-ing well. Finally, I argue that proponents of SKNA can explain the intuitive defectiveness of asserting on the basis of an epistemically bad reason (e.g., a random guess), even when the asserters know the content of their assertion, by arguing that the asserters are epistemically blameworthy.
Aborjinia corallicola sp. n., a new nematode species (Nematoda: Marimermithidae) associated with the bamboo coral Acanella arbuscula (Johnson)
Authors: Westerman Rickard , de Moura Neves Bárbara , Ahmed Mohammed , Holovachov Oleksandr
Published: August 2021

A new species ofAborjiniaÖzdikmen, 2010 is described from the tissues of the cold-water bamboo coralAcanella arbuscula(Johnson) from the northwest Atlantic.Aborjinia corallicolasp. n.is characterized by 18.4–33.2 mm long body in adults; outer labial and cephalic sensilla papilliform and located 14–21 µm from anterior end, amphideal aperture located 22–41 µm from anterior end, excretory pore indistinct, rectum and anal opening functional, convex-conoid tail with broadly rounded terminus, spinneret subventral. It is placed in the genusAborjiniabased on the combination of the following characters: outer labial and cephalic sensilla papilliform in shape and located in one circle, contrary toMarimermisRutsov & Platonova, 1974 (outer labial and cephalic sensilla setiform) andAnanusRubtsov, 1977 andThalassonemaWard, 1933 (outer labial and cephalic sensilla in separate circles, if known). FromAborjinia eulagiscaeTchesunov & Spiridonov, 1985 the new species differs in much shorter body, much shorter tail, presence of caudal glands and spinneret in adults, different host species.Our finding represents the first report of a nematode in a parasitic relationship with a cold-water octocoral. Phylogenetic relationships betweenAborjiniaand other nematodes are analyzed based on 18S rDNA sequences. Summary of all presently known species and genera of the family Marimermithidae is also given.
Understanding Test Modalities of Tire Grip and Laboratory-Road Correlations with Modeling
Authors: Salehi Marzieh , Noordermeer Jacques W. M. , Reuvekamp Louis A. E. M. , Blume Anke
Published: August 2021

The present study is meant to obtain tribological insight into the interface of a rolling rubber wheel on a counter-surface disk based on the work of the previous study Salehi et al. (Tribol Lett 68(1):37, 2020), in which a new test method was developed to rapidly predict tire grip in a laboratory environment. A Laboratory Abrasion Tester (LAT100) was used and exploited as a tribometer. This opened a new cost- and time-effective horizon for tire material development in a laboratory environment rather than having to test tread compounds by building full-scale tires. The method was validated by a comprehensive study for six different tire tread compositions, by correlating the laboratory data for solid rubber wheels as LAT100 specimens with real tire results in two test modalities: lateral (α) and longitudinal (κ) sweep tests on a dry road. It was demonstrated that the LAT100 can be exploited to simulate the $$\alpha$$
α
-sweep tire tests, but not the $$\kappa$$
κ
-sweep. The dynamics and physics of a rolling rubber wheel on a counter-surface disk of the LAT100 test step-up are investigated utilizing the renowned physical “brush model” in comparison to full-scale tire tests. The type of test modality leads to different friction mechanisms in the contact patch even at similar test conditions. This is substantiated by recognizing the two regions: stationary and non-stationary, in the contact area which results in different friction components and mechanisms. The behavior of the rolling wheel in lateral and longitudinal movements at the same test conditions is comparable if the contributions of the mentioned regions in the contact area are similar.
On Opening Crack Propagation in Viscoelastic Solids
Authors: Persson B. N. J.
Published: August 2021

We show that the Persson-Brener theory of crack propagation in viscoelastic solids gives a viscoelastic fracture energy factor $$G/G_0 = 1+f$$

G
/

G
0

=
1
+
f

which is nearly the same as the viscoelastic factor obtained using the cohesive-zone model. We also discuss finite size effects and comment on the use of crack propagation theories for “solids” with a viscoelastic modulus that vanishes at zero frequency.

Graphical Abstract
Optimal portfolios in the presence of stress scenarios A worst-case approach
Authors: Korn Ralf , Müller Lukas
Published: August 2021

Insurance companies and banks regularly have to face stress tests performed by regulatory instances. To model their investment decision problems that includes stress scenarios, we propose the worst-case portfolio approach. Thus, the resulting optimal portfolios are already stress test prone by construction. A central issue of the worst-case portfolio approach is that neither the time nor the order of occurrence of the stress scenarios are known. Even more, there are no probabilistic assumptions regarding the occurrence of the stresses. By defining the relative worst-case loss and introducing the concept of minimum constant portfolio processes, we generalize the traditional concepts of the indifference frontier and the indifference-optimality principle. We prove the existence of a minimum constant portfolio process that is optimal for the multi-stress worst-case problem. As a main result we derive a verification theorem that provides conditions on Lagrange multipliers and nonlinear ordinary differential equations that support the construction of optimal worst-case portfolio strategies. The practical applicability of the verification theorem is demonstrated via numerical solution of various worst-case problems with stresses. There, it is in particular shown that an investor who chooses the worst-case optimal portfolio process may have a preference regarding the order of stresses, but there may also be stress scenarios where he/she is indifferent regarding the order and time of occurrence.
Reproducibility of diffusion tensor image analysis along the perivascular space (DTI-ALPS) for evaluating interstitial fluid diffusivity and glymphatic function: CHanges in Alps index on Multiple conditiON acquIsition eXperiment (CHAMONIX) study
Authors: Taoka Toshiaki , Ito Rintaro , Nakamichi Rei , Kamagata Koji , Sakai Mayuko , Kawai Hisashi , Nakane Toshiki , Abe Takashi , Ichikawa Kazushige , Kikuta Junko , Aoki Shigeki , Naganawa Shinji
Published: August 2021

Purpose

The diffusion tensor image analysis along the perivascular space (DTI-ALPS) method was developed to evaluate the brain’s glymphatic function or interstitial fluid dynamics. This study aimed to evaluate the reproducibility of the DTI-ALPS method and the effect of modifications in the imaging method and data evaluation.

Materials and methods

Seven healthy volunteers were enrolled in this study. Image acquisition was performed for this test–retest study using a fixed imaging sequence and modified imaging methods which included the placement of region of interest (ROI), imaging plane, head position, averaging, number of motion-proving gradients, echo time (TE), and a different scanner. The ALPS-index values were evaluated for the change of conditions listed above.

Results

This test–retest study by a fixed imaging sequence showed very high reproducibility (intraclass coefficient = 0.828) for the ALPS-index value. The bilateral ROI placement showed higher reproducibility. The number of averaging and the difference of the scanner did not influence the ALPS-index values. However, modification of the imaging plane and head position impaired reproducibility, and the number of motion-proving gradients affected the ALPS-index value. The ALPS-index values from 12-axis DTI and 3-axis diffusion-weighted image (DWI) showed good correlation (r = 0.86). Also, a shorter TE resulted in a larger value of the ALPS-index.

Conclusion

ALPS index was robust under the fixed imaging method even when different scanners were used. ALPS index was influenced by the imaging plane, the number of motion-proving gradient axes, and TE in the imaging sequence. These factors should be uniformed in the planning ALPS method studies. The possibility to develop a 3-axis DWI-ALPS method using three axes of the motion-proving gradient was also suggested.
Enablers and challenges when engaging local communities for urban biodiversity conservation in Australian cities
Authors: Taylor Lucy , Maller Cecily J. , Soanes Kylie , Ramalho Cristina E. , Aiyer Abhilasha , Parris Kirsten M. , Threlfall Caragh G.
Published: August 2021

Across all landscape types, environmental managers work with communities to conserve biodiversity. The effectiveness of conservation practice, however, relies on acknowledging differences in preferences and values of nature. Implementing urban conservation is challenging because cities have diverse social, cultural and ecological attributes, meaning there are no simple solutions for the management or co-management of biodiversity. There is little guidance for urban environmental managers on how to 1) engage local urban communities and 2), implement conservation actions specific to cities and their communities. We conducted semi-structured interviews with 27 environmental managers from government and not-for-profit organizations across five Australian capital cities to 1) explore how environmental managers engaged local communities, and 2) understand the factors that enabled or constrained that engagement in conservation. Our aim was to understand the enablers and constraints of engagement with a view to share insights and patterns in the context of the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) conceptual framework’s recognition of the diversity of values associated with nature’s contributions to people (NCP). We found that urban environmental managers facilitated NCP by working to improve people’s relationship with nature. Interviewees reported a range of enablers for community-based biodiversity conservation, including supportive organizational policies and strategies, community support, engaging Indigenous advisory groups, and deploying multi-use, integrative human-nature designs. Constraints and challenges included a lack of top-down commitment, reliance on individuals, and overly simplistic engagement strategies. Based on these findings, we identified opportunities for improved community engagement relevant to organizations responsible for urban environmental management.
Subgroup identification in individual participant data meta-analysis using model-based recursive partitioning
Authors: Huber Cynthia , Benda Norbert , Friede Tim
Published: August 2021

Model-based recursive partitioning (MOB) can be used to identify subgroups with differing treatment effects. The detection rate of treatment-by-covariate interactions and the accuracy of identified subgroups using MOB depend strongly on the sample size. Using data from multiple randomized controlled clinical trials can overcome the problem of too small samples. However, naively pooling data from multiple trials may result in the identification of spurious subgroups as differences in study design, subject selection and other sources of between-trial heterogeneity are ignored. In order to account for between-trial heterogeneity in individual participant data (IPD) meta-analysis random-effect models are frequently used. Commonly, heterogeneity in the treatment effect is modelled using random effects whereas heterogeneity in the baseline risks is modelled by either fixed effects or random effects. In this article, we propose metaMOB, a procedure using the generalized mixed-effects model tree (GLMM tree) algorithm for subgroup identification in IPD meta-analysis. Although the application of metaMOB is potentially wider, e.g. randomized experiments with participants in social sciences or preclinical experiments in life sciences, we focus on randomized controlled clinical trials. In a simulation study, metaMOB outperformed GLMM trees assuming a random intercept only and model-based recursive partitioning (MOB), whose algorithm is the basis for GLMM trees, with respect to the false discovery rates, accuracy of identified subgroups and accuracy of estimated treatment effect. The most robust and therefore most promising method is metaMOB with fixed effects for modelling the between-trial heterogeneity in the baseline risks.
Spectroscopic detection of forest diseases: a review (1970–2020)
Authors: Cotrozzi Lorenzo
Published: August 2021

Sustainable forest management is essential to confront the detrimental impacts of diseases on forest ecosystems. This review highlights the potential of vegetation spectroscopy in improving the feasibility of assessing forest disturbances induced by diseases in a timely and cost-effective manner. The basic concepts of vegetation spectroscopy and its application in phytopathology are first outlined then the literature on the topic is discussed. Using several optical sensors from leaf to landscape-level, a number of forest diseases characterized by variable pathogenic processes have been detected, identified and quantified in many country sites worldwide. Overall, these reviewed studies have pointed out the green and red regions of the visible spectrum, the red-edge and the early near-infrared as the spectral regions most sensitive to the disease development as they are mostly related to chlorophyll changes and symptom development. Late disease conditions particularly affect the shortwave-infrared region, mostly related to water content. This review also highlights some major issues to be addressed such as the need to explore other major forest diseases and geographic areas, to further develop hyperspectral sensors for early detection and discrimination of forest disturbances, to improve devices for remote sensing, to implement long-term monitoring, and to advance algorithms for exploitation of spectral data. Achieving of these goals will enhance the capability of vegetation spectroscopy in early detection of forest stress and in managing forest diseases.
SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution
Authors: Maraschi AnnaMaria , Gumina Valentina , Dragotto Jessica , Colombrita Claudia , Mompeán Miguel , Buratti Emanuele , Silani Vincenzo , Feligioni Marco , Ratti Antonia
Published: August 2021

The nuclear RNA-binding protein TDP-43 forms abnormal cytoplasmic aggregates in the brains of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) patients and several molecular mechanisms promoting TDP-43 cytoplasmic mislocalization and aggregation have been proposed, including defects in nucleocytoplasmic transport, stress granules (SG) disassembly and post-translational modifications (PTM). SUMOylation is a PTM which regulates a variety of cellular processes and, similarly to ubiquitination, targets lysine residues. To investigate the possible regulatory effects of SUMOylation on TDP-43 activity and trafficking, we first assessed that TDP-43 is SUMO-conjugated in the nuclear compartment both covalently and non-covalently in the RRM1 domain at the predicted lysine 136 and SUMO-interacting motif (SIM, 106–110 residues), respectively. By using the SUMO-mutant TDP-43 K136R protein, we demonstrated that SUMOylation modifies TDP-43 splicing activity, specifically exon skipping, and influences its sub-cellular localization and recruitment to SG after oxidative stress. When promoting deSUMOylation by SENP1 enzyme over-expression or by treatment with the cell-permeable SENP1 peptide TS-1, the cytoplasmic localization of TDP-43 increased, depending on its SUMOylation. Moreover, deSUMOylation by TS-1 peptide favoured the formation of small cytoplasmic aggregates of the C-terminal TDP-43 fragment p35, still containing the SUMO lysine target 136, but had no effect on the already formed p25 aggregates. Our data suggest that TDP-43 can be post-translationally modified by SUMOylation which may regulate its splicing function and trafficking, indicating a novel and druggable mechanism to explore as its dysregulation may lead to TDP-43 pathological aggregation in ALS and FTD.
Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment
Authors: Bade Aditya N. , McMillan JoEllyn M. , Liu Yutong , Edagwa Benson J. , Gendelman Howard E.
Published: August 2021

Dolutegravir (DTG) is a first-line antiretroviral drug (ARV) used in combination therapy for the treatment of human immunodeficiency virus type-1 (HIV-1) infection. The drug is effective, safe, and well tolerated. Nonetheless, concerns have recently emerged for its usage in pregnant women or those of child-bearing age. Notably, DTG-based ARV regimens have been linked to birth defects seen as a consequence of periconceptional usages. To this end, uncovering an underlying mechanism for DTG-associated adverse fetal development outcomes has gained clinical and basic research interest. We now report that DTG inhibits matrix metalloproteinases (MMPs) activities that could affect fetal neurodevelopment. DTG is a broad-spectrum MMPs inhibitor and binds to Zn++ at the enzyme’s catalytic domain. Studies performed in pregnant mice show that DTG readily reaches the fetal central nervous system during gestation and inhibits MMP activity. Postnatal screenings of brain health in mice pups identified neuroinflammation and neuronal impairment. These abnormalities persist as a consequence of in utero DTG exposure. We conclude that DTG inhibition of MMPs activities during gestation has the potential to affect prenatal and postnatal neurodevelopment.
The Interregional Migration of Human Capital: The Case of “First-Class” University Graduates in China
Authors: Cui Can , Wang Yifan , Wang Qiang
Published: August 2021

Human capital has been acknowledged as a key driver for innovation, thereby promoting regional economic development in the knowledge era. University graduates from China’s “first-class” universities—the top 42 universities, included in the “double first-class” initiative, are considered highly educated human capital. Their migration patterns will exert profound impacts on regional development in China, however, little is known about the migration of these elite university graduates and its underlying driving forces. Using data from the 2018 Graduate Employment Reports, this study reveals that the uneven distribution of “first-class” universities and regional differentials largely shaped the migration of graduates from the university to work. Graduates were found aggregating in eastern first-tier cities, even though appealing talent-orientated policies aimed at attracting human capital had been launched in recent years by second-tier cities. Employing negative binomial models, this study investigates how the characteristics of the city of university and destinations affect the intensity of flows of graduates between them. The results showed that both jobs and urban amenities in the university city and destination city exert impacts on the inflow volume of graduates; whereas talent attraction policies introduced by many second-tier cities are found not to exert positive effects on attracting “first-class” university graduates presently. The trend of human capital migration worth a follow-up investigation, particularly given ongoing policy dynamics, and would shed light on the regional development disparities in China.
Thoughts on the Ageing Body
Authors: Ghillani Francesca
Published: August 2021

Recent studies have taken into account the fact that the lives of older people have changed drastically in the past fifty years. Older people today engage more with society and are also expected to maintain an active role in their communities. In order to maintain a positive social status, todays older adults need both to challenge negative stereotypes and also to achieve the “unachievable” positive representations in the media. Society plays a complex game of bodily images: the artificial image of the human body in the media, the image that individuals try to project, and the image that society reflects back to the individual. When the three don’t coincide, the collision creates a distancing effect. To truly understand the lived experiences of older adults in contemporary society we must explore the changing perceptions of the body. This review will illustrate the arguments both classical and contemporary through an exploration of the ageing female body, which remains the focus of most of the literature.
Youth Encounters with Internet Pornography: A Survey of Youth, Caregiver, and Educator Perspectives
Authors: Healy-Cullen Siobhán , Taylor Joanne E. , Ross Kirsty , Morison Tracy
Published: August 2021

Despite international inquiry regarding young people’s encounters with Internet pornography (IP), there is a lack of knowledge about how their caregivers (parents or guardians) and educators perceive these encounters in comparison to young people. Such knowledge is critical to understanding the synergies and discrepancies that might exist between these key stakeholder groups (youth, caregivers and educators) and across genders, to subsequently inform how to best support youth in navigating IP. To this end, the present study describes youth (16–18-year olds) encounters with IP, as well as caregiver and educator perceptions of these encounters. An online survey was completed by 256 youth and 217 caregivers and educators recruited from nine schools with an existing investment in sexuality education in Aotearoa, New Zealand. Similar to global trends, this group of young New Zealanders were familiar with IP and patterns of encounters were gendered. However, there were varied understandings between stakeholder groups and across genders as to why and how these encounters occur. Understanding the ways youth encounter IP—and exploring how caregivers and educators perceive these encounters—serves as a springboard for future research that considers the broader socio-cultural context within which these perspectives are constructed.
Identification of suitable sites for managed aquifer recharge under semi-arid conditions employing a combination of numerical and analytical techniques
Authors: Alkhatib Jafar , Engelhardt Irina , Sauter Martin
Published: August 2021

Overpumping or overexploitation of groundwater is one of the major threats for aquifer systems in arid and semi-arid areas. Managed aquifer recharge (MAR) has been suggested by many researchers as a sustainable and effective method to alleviate negative impacts of overpumping. Optimizing artificial recharge considers the selection of suitable MAR sites in terms of surface and subsurface characteristics. While surface characteristics at potential MAR sites could be modified (e.g. slope, soil texture, etc.), subsurface characteristics cannot be changed through engineering work. Characteristics of the aquifer, such as depth to groundwater, play an important role in determining the capability of an aquifer to store a specific volume of infiltrated water. Currently, only a limited number of quoted researches are available that consider factors related to aquifer characteristics and the range of these factors to identify optimal MAR sites. In this study, a new approach is presented, that employs numerical groundwater modeling to generate MAR suitability maps considering sub-surface characteristics, such as depth-to-groundwater, aquifer transmissivity and specific yield. Multiple model-runs are conducted to simulate groundwater table response with respect to the volume of infiltrated water. Simulation results are used to calibrate a groundwater mound empirical equation that calculates the groundwater level increase as a function of the transmissivity and infiltrated water volume for a given value of aquifer’ specific yield, range of vertical hydraulic conductivities and a specific design and operation conditions of the MAR system. The empirical equation is employed in GIS to spatially calculate the height of groundwater mound beneath a hypothetical MAR site and to generate, based on that, suitability maps for MAR implementation. Assuming that MAR structures capture the median of monthly surface runoff rates at the respective wadi (catchment area), suitability maps are generated for different configurations/scenarios of aquifer hydraulic conductivity in a parameter study. The results highlight the importance of integrating aquifer characteristics (geometry and hydraulic parameters) and expected magnitudes and fluxes of infiltration water in delineating suitable sites for MAR.
Using unmanned aerial vehicle photogrammetry for digital geological surveys: case study of Selmun promontory, northern of Malta
Authors: Colica Emanuele , D’Amico Sebastiano , Iannucci Roberto , Martino Salvatore , Gauci Adam , Galone Luciano , Galea Pauline , Paciello Antonella
Published: August 2021

In recent years, we have been witnessing the widespread use of low-cost, increasingly high-performance Unmanned Aerial Vehicles, or UAVs, equipped with a large number of sensors capable of extracting detailed information on several scales and in an immediate manner. This study was motivated by the need to perform a geological survey in an area with difficult physical access, and to compare the results with those from conventional surveys. Here we used a Multirotor UAV equipped with a high definition RGB camera and the digital photogrammetry technique to reconstruct a three-dimensional model of the Selmun promontory, located in the northern part of the island of Malta (central Mediterranean Sea). In this area, the evident cliff retreat is linked to landslide processes involving the outcropping geological succession, characterized by the over position of stiff limestones on ductile clays. Such an instability process consists of a lateral spreading associated with toppling and fall of different-size rock blocks. Starting from the 3D model obtained from the UAV-photogrammetry, a digital geological-structural survey was performed in which we identified the spatial geometry of the fractures that characterize the area of the Selmun promontory by measuring strike, dip and dip direction of the fractures with semi-automatic digital tools. Furthermore, we were able to measure the size and volume of singularized rock masses as well as cracks, and their sizes were mapped in a GIS environment that contains a large number of digital structural measures. It is the first application of this type for the Maltese islands and the results obtained with this innovative digital methodology were then compared with those of the traditional field survey of the same area acquired during a previous campaign. This study demonstrated how the innovation of digital geological surveying lies in the possibility of mapping areas and geological features not detectable with traditional methods, mainly due to the high risk associated with the stability of the cliff or, more generally, the inaccessibility of some sites, therefore allowing the user to operate in safety and to detect in detail the most remote rocky outcrops.
Adsorption of chromium (Cr6+) on dead biomass of Salvinia molesta (Kariba weed) and Typha latifolia (broadleaf cattail): isotherm, kinetic, and thermodynamic study
Authors: Singh Asha , Kumar Sunil , Panghal Vishal
Published: August 2021

This study evaluated the adsorption of Cr6+ from aqueous solution using dead biomass of aquatic plants Salvinia molesta (Kariba weed) and Typha latifolia (broadleaf cattail). The batch experiments were carried out to study the effects of pH, adsorbent dose, initial metal concentration, contact time, agitation speed in rotation per minute (rpm), and temperature. Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were used to characterize the adsorbent and analyze the functional groups and morphology of the adsorbent, respectively. The hydroxyl and amine groups were the main functional groups involved in the adsorption. Both adsorbents showed good results at pH 1, metal concentration of 20 mg/L for Cr6+ removal, and adsorption equilibrium was attained within 60 min with 150 rpm at 25 °C. The adsorption rate obtained was above 95% for both the adsorbents at a dose of 0.150 g for S. molesta and 0.8 g for T. latifolia. Isotherm and kinetic models were applied on the adsorption data. The monolayer adsorption capacity (qm) was found to be 33.33 mg/g for S. molesta and 10.30 mg/g for T. latifolia. The Langmuir isotherm was better fitted to S. molesta, while the Freundlich isotherm was better fitted to T. latifolia. It was reported that the pseudo-second-order model (R2 = 0.999) was better fitted to the adsorption data for both the adsorbents. The thermodynamic study was also conducted and found the adsorption process was exothermic and spontaneous. Results revealed the good adsorption potential of S. molesta and T. latifolia, and they can be used for the removal of hexavalent chromium.
In-silico and in-vivo evaluation of sesamol and its derivatives for benign prostatic hypertrophy
Authors: Shah Abhishek , Shah Aarti Abhishek , Nandakumar Krishnadas , Kumar Avinash , Pai Aravinda , Lobo Richard
Published: August 2021

Pharmacological treatment for BPH includes 5-α reductase inhibitors as Finasteride and Dutasteride as a monotherapy or in combination with antimuscarinic drugs, alpha-blockers, 5-phosphodiesterase inhibitor drugs. Androgen receptor inhibitors revealed several adverse events as decreased libido, erectile dysfunction, ejaculatory dysfunction, and gynecomastia. Hence, the emergence of complementary and alternative medications having safety profile—preferably, edible natural products—would be highly desirable. In-silico studies based on Maestro Molecular Modelling platform (version 10.5) by Schrӧdinger, LLC was used to identify the lead molecules. The in-vivo activity studied on rats gave the positive results. The findings based on experiments as antioxidant parameters showed the potential to quench the free radicals. The significant results were also seen in prostatic index and histopathological studies supported the above findings. Based on these data, sesamol and derivative have proven efficacy in protecting against testosterone induced BPH.
Constraints in inflationary magnetogenesis
Authors: Shtanov Yuri
Published: August 2021

We discuss popular models of inflationary and early post-inflationary magnetogenesis and present model-independent upper bounds on the strength of the resulting magnetic fields imposed by the considerations of weak coupling, back-reaction and Schwinger effect.
Keypoint detectors and texture analysis based comprehensive comparison in different color spaces for automatic detection of the optic disc in retinal fundus images
Authors: Akyol Kemal , Şen Baha
Published: August 2021

Detection of the optic disc which has similar brightness with the hard and soft exudate lesions seen in the early stage of diabetic retinopathy is very difficult due to different light conditions and contrast values. Automatic detection of these lesions by expert systems in the medical field is very important. In this context, we propose a new approach based on the analysis of color spaces, keypoint detectors, and texture for retinal fundus images. If the keypoint information is contained within the actual optic disc region, this is an important consideration for the automated detection of the optic disc. This study can be divided into five sections, respectively, image preprocessing, image processing, keypoint detection, texture analysis, and performance evaluation. The analyses of patch images compatible with the keypoints obtained from the Red–Green–Blue (RGB) image and its color channels were carried out. The performance of the study was validated on the Digital Retinal Images for Vessel Extraction public dataset. According to the results, Local Binary Pattern texture analysis performed in region of interest around keypoints detected by different keypoint detectors presented good performance in RGB and green channel images.
Exploring Male Multiple Orgasm in a Large Online Sample: Refining Our Understanding
Authors: Griffin-Mathieu Gabrielle , Berry Michael , Shtarkshall Ronny A. , Amsel Rhonda , Binik Yitzchak M. , Gérard Marina
Published: August 2021

Background

The scientific literature on multiple orgasm in males is small. There is little consensus on a definition, and significant controversy about whether multiple orgasm is a unitary experience.

Aims

This study has 2 goals: (i) describing the experience of male multiple orgasm; (ii) investigating whether there are different profiles of multiple orgasm in men.

Methods

Data from a culturally diverse online convenience sample of 122 men reporting multiple orgasm were collected. Data reduction analyses were conducted using principal components analysis (PCA) on 13 variables of interest derived from theory and the existing literature. A K-means cluster analysis followed, from which a 4-cluster solution was retained.

RESULTS

While the range of reported orgasms varied from 2 to 30, the majority (79.5%, N = 97) of participants experienced between 2 and 4 orgasms separated by a specific time interval during which further stimulation was required to achieve another orgasm. Most participants reported maintaining their erections throughout and ejaculating with every orgasm. Age was not a significant correlate of the multiple orgasm experience which occurred more frequently in a dyadic context. Four different profiles of multiorgasmic men were described.

Strengths & Limitations

This study constitutes a rare attempt to collect systematic self-report data concerning the experience of multiple orgasm in a relatively large sample. Limitations include the lack of validated measures, memory bias associated with self-reported data and retrospective designs, the lack of a control group and of physiological measurement.

CONCLUSION

Our study suggests that multiple orgasm in men is not a unitary phenomenon and sets the stage for future self-report and laboratory study.
Exploratory Factor Analysis of Unusual Sexual Interests
Authors: Schippers Eveline E. , Smid Wineke J. , Huckelba Anna Laura , Hoogsteder Larissa M. , Beekman Aartjan T.F. , Smit Jan H.
Published: August 2021

Background

Unusual sexual interests are largely intercorrelated, yet not much is known about underlying patterns of clusters between various sexual interests.

Aim

To identify underlying clusters of unusual sexual interests using exploratory factor analysis.

Methods

We conducted exploratory factor analysis with self-reported interest in a wide variety of unusual sexual acts for an online, international sample (N = 669; 61% female), and for women and men separately. Factor regression weights were correlated to self-reported sex life satisfaction, sexual outlet, and psychiatric symptoms.

Outcomes

Participants rated the attractiveness of 50 unusual sexual activities, and reported on their sex life satisfaction (Arizona Sexual Experiences Scale), sexual outlet, and symptoms regarding ADHD (Adult ADHD Self-Report Screening Scale for DSM-5), depression, anxiety, and stress (Depression, Anxiety, and Stress Scale).

RESULTS

We identified 5 factors of unusual sexual interests that were largely comparable for women and men: submission/masochism, forbidden sexual activities, dominance/sadism, mysophilia (attraction to dirtiness or soiled things), and fetishism. For women, unusual sexual interests related to more psychiatric symptoms and higher sexual outlet, whereas this relation was less explicit for men.

Clinical Implications

Different factors of unusual sexual interests may serve different underlying functions or motivations, for instance related to sexual, and emotional regulation. A better understanding of the nature of unusual sexual interests is important to be able to influence sexual interests that are unwanted or cause damage to others.

Strengths & Limitations

Strength of this study include its anonymity, the avoidance of sexual orientation effects, and the possibility to indicate only a slight endorsement toward sexual items. Limitations include the sample’s generalizability and the truthfulness of online responding.

CONCLUSION

Unusual sexual interests could be clustered into 5 factors that were largely comparable for women and men: submission/masochism, forbidden sexual activities, dominance/sadism, mysophilia, and fetishism.
Unpacking Creativity
Authors: Pérez Sobrino Paula , Littlemore Jeannette , Ford Samantha
Published: August 2021

Figurative communication (the use of metaphor, metonymy, hyperbole and irony) provides economy of expression, clarity, persuasiveness, politeness, evaluation, and communication of emotions. However, it also increases the potential for misunderstanding in situations when people lack shared background knowledge. This book combines theoretical frameworks with empirical studies that measure the effectiveness of different approaches to the use of figurative language in advertisements, to show how to maximise the benefits of creative metaphor and metonymy in global advertising. It highlights how subtle differences in colour, layout, and combinations of different kinds of figurative language affect the reception and appreciation of creative advertising, shedding new light on the nature of figurative communication itself. With a balance between theory, experiments and practical case studies, this book is accessible for academics in linguistics and communication studies, as well as advertising and marketing professionals.
A Benchmark to Test Generalization Capabilities of Deep Learning Methods to Classify Severe Convective Storms in a Changing Climate
Authors: Molina Maria J. , Gagne David John , Prein Andreas F.
Published: August 2021

This is a test case study assessing the ability of deep learning methods to generalize to a future climate (end of 21st century) when trained to classify thunderstorms in model output representative of the present‐day climate. A convolutional neural network (CNN) was trained to classify strongly rotating thunderstorms from a current climate created using the Weather Research and Forecasting model at high‐resolution, then evaluated against thunderstorms from a future climate and found to perform with skill and comparatively in both climates. Despite training with labels derived from a threshold value of a severe thunderstorm diagnostic (updraft helicity), which was not used as an input attribute, the CNN learned physical characteristics of organized convection and environments that are not captured by the diagnostic heuristic. Physical features were not prescribed but rather learned from the data, such as the importance of dry air at mid‐levels for intense thunderstorm development when low‐level moisture is present (i.e., convective available potential energy). Explanation techniques also revealed that thunderstorms classified as strongly rotating are associated with learned rotation signatures. Results show that the creation of synthetic data with ground truth is a viable alternative to human‐labeled data and that a CNN is able to generalize a target using learned features that would be difficult to encode due to spatial complexity. Most importantly, results from this study show that deep learning is capable of generalizing to future climate extremes and can exhibit out‐of‐sample robustness with hyperparameter tuning in certain applications.