bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of some cost-effective technologies for a routine clinical pathology laboratory
Authors: Vázquez Mercedes , Anfossi Laura , Ben-Yoav Hadar , Diéguez Lorena , Karopka Thomas , Della Ventura Bartolomeo , Abalde-Cela Sara , Minopoli Antonio , Di Nardo Fabio , Shukla Vikas Kumar , Teixeira Alexandra , Tvarijonaviciute Asta , Franco-Martínez Lorena
Published: September 2021

Cost-effective technologies allow >85% economical savings, making clinical pathology more accessible worldwide.
Probing the potential of ureasil-poly(ethylene oxide) as a glyphosate scavenger in aqueous milieu: force-field parameterization and MD simulations
Authors: Misturini Alechania , Heinzelmann Germano , Parreira Renato L. T. , Molina Eduardo F. , Caramori Giovanni F.
Published: September 2021

The intensive use of glyphosate in conventional agriculture and its high solubility in water have led to contamination of aqueous systems worldwide.
Fabrication of strontium included hafnium oxide thin film based Al/Sr:HfO2/n-Si MIS-Schottky barrier diodes for tuned electrical behavior
Authors: Harishsenthil P. , Chandrasekaran J. , Thangaraju D. , Balasubramani V.
Published: September 2021

Synthesis of Sr included HfO2 for fabrication of a Schottky barrier diode.
The charge transfer effect on SERS in a gold-decorated surface defect anatase nanosheet/methylene blue (MB) system
Authors: Li Chang , Wu Chuanqiang , Zhang Ke , Chen Mingqiang , Wang Yishuang , Shi Jingjing , Tang Zhiyuan
Published: September 2021

The increase in the transition route of the CT process enhances the Raman scattering of MB.
Conjugated polymers – a versatile platform for various photophysical, electrochemical and biomedical applications: a comprehensive review
Authors: Palani Purushothaman , Karpagam Subramanian
Published: September 2021

Tuneable properties of conjugated polymers are attractive for use in multiple domains like optical, electronic and biological applications.
Evolution and applications of polymer brush hypersurface photolithography
Authors: Valles Daniel J. , Zholdassov Yerzhan S. , Braunschweig Adam B.
Published: September 2021

Hypersurface photolithography creates arbitrary polymer brush patterns with independent control over feature diameter, height, and spacing between features, while controlling composition along a polymer chain and between features.
Synthesis and characterization of polyaniline–hydrotalcite–graphene oxide composite and application in polyurethane coating
Authors: Tran Boi An , Duong Huynh Thanh Linh , To Thi Xuan Hang , Phan Thanh Thao
Published: September 2021

Corrosion protection: PAN–HG performed effect of 95.49% protection of CT3-steel in NaCl 3.5%. PU(PAN–HG) coating provides good corrosion protection with complex mechanism of high barrier, ion-exchange and e−trapping to HG structure.
Alchemical absolute protein–ligand binding free energies for drug design
Authors: Khalak Y. , Tresadern G. , Aldeghi M. , Baumann H. M. , Mobley D. L. , de Groot B. L. , Gapsys V.
Published: September 2021

Molecular dynamics based absolute protein–ligand binding free energies can be calculated accurately and at large scale to facilitate drug discovery.
Allosteric inhibition of SARS-CoV-2 3CL protease by colloidal bismuth subcitrate
Authors: Tao Xuan , Zhang Lu , Du Liubing , Liao Ruyan , Cai Huiling , Lu Kai , Zhao Zhennan , Xie Yanxuan , Wang Pei-Hui , Pan Ji-An , Zhang Yuebin , Li Guohui , Dai Jun , Mao Zong-Wan , Xia Wei
Published: September 2021

Colloidal bismuth subcitrate (CBS) is an allosteric inhibitor of 3-chymotrypsin-like protease (3CLpro) in SARS-CoV-2. CBS binding causes dimeric 3CLpro dissociation and proteolytic dysfunction, leading to the suppression of SARS-CoV-2 replication.
A new 3D metallic carbon allotrope composed of penta-graphene nanoribbons as a high-performance anode material for sodium-ion batteries
Authors: Li Siyan , Shen Yiheng , Ni Dongyuan , Wang Qian
Published: September 2021

We propose a new 3D metallic carbon allotrope constructed by penta-graphene nanoribbons as promising anode material for sodium-ion batteries, which expands the family of pentagon-based carbon allotropes from 2D penta-graphene to 3D metallic material.
Aligned wave-like elastomer fibers with robust conductive layers via electroless deposition for stretchable electrode applications
Authors: Li Yan , Chen Yi , Yang Yi , Gu Jun-Di , Ke Kai , Yin Bo , Yang Ming-Bo
Published: September 2021

The robust conductive layer formed on wave-like fibers by electroless deposition endows electrodes with high stretchability and low resistance.
Flavin oxidation state impacts on nitrofuran antibiotic binding orientation in nitroreductases
Authors: Toogood Helen S. , Scrutton Nigel S.
Published: September 2021

Nitroreductases catalyse the NAD(P)H-dependent nitro reduction in nitrofuran antibiotics, which activates them into cytotoxic molecules leading to cell death. The design of new effective nitrofuran antibiotics relies on knowledge of the kinetic mechanism and nitrofuran binding mode of microbial nitroreductases NfsA and NfsB. This has been hampered by multiple co-crystallisation studies revealing ligand binding in non-electron transfer competent states. In a recent study by Day et al. (2021) the authors investigated the likely reaction mechanism and mode of nitrofurantoin binding to NfsA using potentiometry, global kinetics analysis, crystallography and molecular dynamics simulations. Their findings suggest nitrofurantoin reduction proceeds via a direct hydride transfer from reduced FMN, while the crystallographic binding orientation is an inhibitory complex. Molecular dynamics simulations suggest ligand binding orientations is dependent on the oxidation state of the FMN. This study highlights the importance of utilising computational studies alongside traditional crystallographic approaches, when multiple stable ligand binding orientations can occur.
Ultra diffuse galaxies in the MATLAS low-to-moderate density fields
Authors: Marleau Francine R. , Habas Rebecca , Poulain Mélina , Duc Pierre-Alain , Müller Oliver , Lim Sungsoon , Durrell Patrick R. , Sánchez-Janssen Rubén , Paudel Sanjaya , Lammim Ahad Syeda , Chougule Abhishek , Bílek Michal , Fensch Jérémy
Published: September 2021

Recent advances in deep dedicated imaging surveys over the past decade have uncovered a surprisingly large number of extremely faint low surface brightness galaxies with large physical sizes called ultra diffuse galaxies (UDGs) in clusters and, more recently, in lower density environments. As part of the Mass Assembly of early-Type GaLAxies with their fine Structures (MATLAS) survey, a deep imaging large program at the Canada-France-Hawaii Telescope (CFHT), our team has identified 2210 dwarf galaxies, 59 (∼3%) of which qualify as UDGs. Averaging over the survey area, we find ∼0.4 UDG per square degree. They are found in a range of low to moderate density environments, although 61% of the sample fall within the virial radii of groups. Based on a detailed analysis of their photometric and structural properties, we find that the MATLAS UDGs do not show significant differences from the traditional dwarfs, except from the predefined size and surface brightness cut. Their median color is as red as the one measured in galaxy clusters, albeit with a narrower color range. The majority of the UDGs are visually classified as dwarf ellipticals with log stellar masses of ∼6.5 − 8.7. The fraction of nucleated UDGs (∼34%) is roughly the same as the nucleated fraction of the traditional dwarfs. Only five (∼8%) UDGs show signs of tidal disruption and only two are tidal dwarf galaxy candidates. A study of globular cluster (GC) candidates selected in the CFHT images finds no evidence of a higher GC specific frequencySNfor UDGs than for classical dwarfs, contrary to what is found in most clusters. The UDG halo-to-stellar mass ratio distribution, as estimated from the GC counts, peaks at roughly the same value as for the traditional dwarfs, but spans the smaller range of ∼10 − 2000. We interpret these results to mean that the large majority of the field-to-group UDGs do not have a different formation scenario than traditional dwarfs.
Surface sterilization method for reducing contamination of Clinacanthus nutans nodal explants intended for in-vitro culture
Authors: Hashim Saiyidah Nafisah , Ghazali Siti Zulaiha , Sidik Norrizah Jaafar , Chia-Chay Tay , Saleh Azani
Published: September 2021

Surface sterilization is a vital step in preparation of healthy and viable explants in tissue culture. Most surface contaminants can be eliminated by surface sterilization with a suitable sterilizing agent. The study aimed to present an effective disinfection method for Clinacanthus nutans shoot regeneration using nodal segments. A total of four different sterilization approaches were conducted by treating nodal explants with various concentrations of sterilizing agent. Sterilizing agents used were Rhizophora apiculata Pyroligneous acid (PA), sodium hypochlorite (Clorox) thiophanate-methyl (fungicide), and Mercuric chloride (HgCl2). Nodal explant then was cultured on plant growth regulator-free Murashige and Skoog (MS) basal medium. This study sterilizing agents revealed that PA showed strong bactericidal activity. However, it led to a high number of fungal contaminations. The pyroligneous acid did not exhibit a strong potential as a disinfectant for C. nutans nodal explant. Overall, HgCl2 exhibits the best reduction in fungal contamination and gives a significant result with thiophanate-methyl fungicide. Surface sterilization with mercuric chloride (0.2%) for 1 hour was the optimum concentration and duration, which resulted in the highest percentage of nodal explant survival and viability. All viable nodal segments developed into shoots. It had been concluded that the best surface sterilization agent was HgCl2.
Growth and yield of shallot using KCl fertilizer at peatlands in Central Kalimantan, Indonesia
Authors: Suparman  , Bhermana Andy , Nuraini Laela , Nugroho Wahyu A , Mulyono Joko
Published: September 2021

In order to develop horticultural commodities, especially for shallots (Allium ascalonicum L), Central Kalimantan province attempts to develop the areas as new agricultural centers on sub-optimal lands. Peatlands have been recognized as potential land for agriculture and shallot development has been carried out since 2013. For shallot, KCl fertilizer plays role in facilitating photosynthesis process, growth plant at the starting level, strengthen the stem and reduce yield decay. The objective of this study was to determine the effect of addition of KCL fertilizer on growth and productivity of shallots (Allium ascalonicum L) in peatlands. This study was conducted in Palangka Raya starting from August 2019 to December 2019. Statistical approach used randomized block design (RBD) with 5 treatments and 4 replications. The treatments given involved without fertilization K0 = 0 kg/ha, K1 = 50 kg/ha, K2 = 100 kg/ha, K3 = 150 kg/ha, K4 = 200 kg/ha. Several parameters observed included plant height, number of leaves, number of tillers, weight of wet biomass, dry biomass and bulb weight. The results showed that the application with addition of KCl with dosage of 150 kg/ha showed a higher yield and it was significantly different from other KCl dosage treatments.
The projection of rice production in Java Island to support Indonesia as the world food granary
Authors: Susanti Erni , Dewi Elsa Rakhmi , Surmaini Elza , Sopaheluwakan Ardhasena , Linarko Aji , Syahputra Muhammad Ridho
Published: September 2021

The use of climate projections such as Cordex-SEA with crop simulation models can determine the projections of rice productivity in the future especially to meet the Indonesian vision as world food granary by 2045.This study aimed to 1) evaluate the projection of rice productivity and 2) compile a map of projected changes at the district level in Java Island in 2021-2035 and 2036-2050 for the RCP4.5 and RCP8.5 scenarios. The Agricultural Production System Simulator (APSIM) results based on the CSIROMK3.6 climate projection model for both scenarios in 2021-2035 showed that the impact of high productivity was high during the rainy season compared to the dry season. Districts with the increase of productivity indicate that these areas can be maintained or developed for rice crop. For the RCP4.5 scenario (rainy season) in the irrigated area, 41 districts out of 191 districts in Java Island had the class of up-high productivity changes. For the period of 2036 to 2050, there were fewer districts that had up-high productivity changes. The APSIM simulation results using HadGEM2 climate projections indicated more districts had decreased productivity in both year periods for both scenarios.
Changes in caffeine of fermented Liberica coffee beans cv. Liberoid Meranti on roasting levels
Authors: Wibowo Nendyo Adhi , Mangunwardoyo Wibowo , Santoso Tri Joko , Yasman
Published: September 2021

One of the varieties of Liberica coffee in Indonesia is the Liberoid Meranti coffee. Fermentation technology and the roasting temperature of Liberica coffee are needed in changing the composition of caffeine in coffee beans. The aim of this research was to see the caffeine content of the Liberica coffee beans cv. Liberoid Meranti fermented by hydrolytic bacteria on levels at a light, medium, and dark roasting temperatures. Coffee fermentation was carried out using the wet processing method and a roasting temperature of 150oC, 175oC, 200oC, and caffeine analysis was carried out by UV-Visible spectrophotometry. The data obtained from each parameter based on roasting levels were processed using the statistical application of Minitab version 16 for Windows and analyzed using ANOVA with a level of 5%. If there is a significant difference from the F-test result (p<0.05), then proceed with the post hoc test. The results showed that all samples contain large amounts of caffeine with various concentrations. The level concentration of caffeine in light roast samples in the range of 10,80 ppm-12,52 ppm, medium roast samples in the range of 11,46 ppm-14,08 ppm, and dark roast samples in the range of 14,49 ppm-16,94 ppm. The caffeine content in fermented Liberica coffee bean experienced a significant difference. The fermentation and roasting process of coffee beans is a complex compound process that can cause changes in caffeine levels.
Growth responses of potted chrysanthemum “Armita Agrihorti” variety at various concentration of bio-urine liquid fertilizer
Authors: Yuniarti  , Meilasari Rika , Aznur Firmansyah
Published: September 2021

Nutrients are needed to increase crop production. Liquid fertilizer (bio-urine), which macro elements, easily absorbed by plants and quickly shows results with optimum concentration, is one of the organic fertilizers that can be used as a trigger for the growth of potted chrysanthemums. The aim of this study to determine the optimum concentration of bio-urine in potted chrysanthemum cultivation. This research was conducted from October to December 2020 at West Sumatera AIAT’s greenhouse on altitude of 1000 m above sea level, was designed with a Randomized Complete Block Design and five replications. Observed consist of five concentrations of bio-urine, namely (1) 200 ml L-1of water, (2) 100 ml L-1of water, (3) 66.67 ml L-1of water, (4) 50 ml L-1and (5) 40 ml L-1of water. Parameters observed were plant height, number and length of internodes, number of branches, stem diameter, flower initiation, number and diameter of flowers, and petiole length. The result shows that Bio-urine with a concentration of 100 ml L-1 of water produces potted chrysanthemum with optimum parameters of plant height, number of internodes, number of branches, stem diameter, number of flowers, flower diameter, and petiole length.
Effect of planting system and seedling number on growth and rice yield rice Inpari-IR-Nutri Zinc
Authors: Kartinaty Tietyk , Massinai Rustan , Fardenan Deden , Warman Riki
Published: September 2021

Rice Inpari-IR-Nutri Zinc is a biofortified product with a high zinc content compared to other types of rice. This study aimed to obtain the best planting system and the number of seeds in increasing the growth and yield of Inpari IR Nutri Zinc. This study used a Divided Plot Design which was repeated four times. There was a total of 32 treatment combinations. The planting system (S) is placed as the main plot consisting of S1 (4: 1 Legowo Planting System) and S2 (Tile Planting System), while the number of seeds (J) as sub-plots consists of J1 (1 seed), J2 (3) seeds), J3 (3 seeds) and J4 (7 seeds). The planting system and the number of seeds had a significant effect on the variables of plant height, total tiller number, number of productive tillers, the weight of 1,000 seeds, panicle length, and rice production of Inpari IR Nutri Zinc. The use of seeds of 1 and 3 plants produced 4.74 and 4.60 tons/ha. The legowo 4: 1 planting system had 4.88
Effectivenes of NPK compound (10-30-20) to improve growth and yield of hybrid maize on vertisol soil
Authors: Sihombing Donald , Hermanto Catur , Asnita Rika , Handayati Wahyu , Sa’adah Sri Zunaini , Sugiono  , Abubakar
Published: September 2021

To determine the effectiveness of NPK compound (10-30-20) fertilizer to maize growth and yield, a study was conducted on vertisol soil of the rainfed rice field in Gambir Kuning village, Kraton District Pasuruan Regency, from September 2020 until February 2021. The study was arranged in randomized block design with four replications. As the treatment i.e., A. control (without inorganic fertilizer), B. standard/local recommendation (NPK 15-15-15) 300 kg, C. NPK (10-30-20) 100 kg, D. NPK (10-30-20) 200 kg, E. NPK (10-30-20) 300 kg, F. NPK (10-30-20) 400 kg, G. NPK (10-30-20) 500 kg ha-1. Except for control, all treatments were fertilized with 200 kg Urea and 100 kg ZA. P27 hybrid maize variety was used as an indicator plant. The results showed that the applications of NPK compound ((10-30-20) were increasing plant growth and yield effectively. The optimum dosage of NPK (10-30-20) was 499.55 kg ha-1. Treatment F produced the highest yield (6.83 tons ha-1) and was significantly different from the control (4.13 tons ha-1) and higher than the standard (6.24 tons ha-1). This treatment also gave the highest RAE value (127,55).
Feasibility of soybean cultivation technology in rainfed area with acidic soil in Lampung
Authors: Elisabeth Dian Adi Anggraeni , Rahmianna Agustina Asri , Harsono Arief , Ginting Erliana
Published: September 2021

In 2017, Indonesian Legumes and Tuber Crops Research Institute (Iletri) introduced a package of soybean cultivation technology in rainfed area with non-acidic soil in Maros, South Sulawesi named Biodetas which was able to produce the yield of 2.1-3.2 t/ha. In 2018, Biodetas was developed to East Lampung, Lampung which has specific rainfed area with acidic soil. Therefore, the technology has been modified by the addition of dolomite and named as “specific Biodetas”. To finding out the results of “specific Biodetas” application in improving soybean productivity and farmers’ income, there are three treatments involved: P1 = Doing tillage and planting with manual dibbling tool, P2 = Doing tillage and planting with simple planting tool, and P3 = No tillage and planting with simple planting tool. P2 and P3 were specific Biodetas adjusting to the existing farmers’ cultivation. The yield of specific Biodetas were 1.362-1.727 t/ha. P3 produced the highest yield and the highest total benefit of IDR 6,670,500/ha. The specific Biodetas adjusting to the existing farmers’ cultivation could provide additional benefit of IDR 640,000 for P2 and IDR 3,706,000 for P3. MBCR values of P2 and P3 were 3.64 and 4.92, respectively, reflected that the technologies were feasible to be applied.
The impact of Integrated Crop Management technical guidance of cayenne pepper crops to the farmer’s in Klungkung Regency, Bali
Authors: Rinaldi Jemmy , Arya Nyoman Ngurah , Mahaputra I Ketut , Suharyanto  , Trisnawati Ni Wayan , Sari Anella Retna Kumala , Jati Eko Nugroho
Published: September 2021

Cayenne pepper productivity in Bali Province tend to decline predicted caused by the traditionally cayenne pepper cultivation applied by farmers related. One of effort to optimize the cayenne pepper productivity is implementation of Integrated Crop Management (ICM) technology in cayenne pepper cultivation. ICM technology can be introduced to the farmers related by technical guidance method at early stage. The goal of its technical guidance method was to find out the changes of farmer’s knowledge and attitude to the ICM technology of cayenne pepper cultivation. Study was conducted in Klungkung Regency used primary data obtained by directly interview using questionnaire to the 30 farmers before and after participate in the ICM technical guidance for cayenne pepper crop cultivation. Collected data was analysed by non-parametric test using Wilcoxon rank sum test. Result indicated that the farmer’s knowledge significant changes to the ICM technology of cayenne pepper cultivation from not know to recognize through this technical guidance method. It was on the same line with the changes of farmer’s attitude namely from hesitate became agree to the ICM component technology of cayenne pepper cultivation. This significance changes of knowledge and attitude were found out in almost all of ICM component technology.
Perception and intention in organic agriculture cultivation in North Maluku Province
Authors: Fuady Ikhsan , Mardianah  , Sutarjo MA Syifaa
Published: September 2021

The green revolution program during the New Order era has left various agricultural problems. Organic agriculture as the antithesis of agricultural development paradigm has long been echoed. However, the intention of farmers to do organic farming is still relatively limited. Many factors influence farmers’ behavior intention, one of which is the perception of agriculture towards the organic farming system. This study aims to describe farmers’ perceptions and intention in organic farming in North Maluku Province, using the UTAUT1 (Venkatest 2003) theoretical framework from venkatest. This study was designed as a quantitative study with a survey approach. The population of this study was vegetable farmers in North Maluku province. The sample of this study was 120 farmers spread across the city of Ternate and Tidore. This research data analysis used descriptive statistics. The results showed that the farmers’ perceptions about organic agricultural cultivation were generally categorized as quite good / moderate. Only 1 indicator of a high perspective, namely farmers’ perceptions of performance expectations or farmers believe that organic farming systems can improve their farming with a value of 3.38 ± 0.6. The intention or intention of farmers to do organic farming is relatively diverse. As many as 36.7 percent have a strong desire, but 33.3 percent have a low intention.
Perceptions and attitudes of the community in Patutrejo Village, Purworejo, Central Java towards Jalawure
Authors: Sanudin
Published: September 2021

Jalawure (Tacca leontopetaloidesL) is a type of plant that has a habitat in the coastal. Tubers of jalawure are used as alternative food ingredients because they contain starch (amylose and amylopectin). Jalawure is known by the coastal communities in Patutrejo Village Grabag Purworejo, Central Java asmureng. However, many people have not known its use. This study aims to determine the perception and attitude of the communitytowards jalawure. Data was collected through interviews with members of the local community and village head. The data obtained were tabulated and analyzed using a Likert Scale. The study was conducted from October 2020 to March 2021. The results showed almost all respondents know jalawure because they had seen jalawure directly either in the yard or garden or in forest areas in their villages. In total, the perception and attitude of the community on cultivation, benefits, processing, and marketing of jalawure are moderate, this is indicated by the value of all statements which show a value of more than 50%. These positive perceptions and attitudes can be used for the development of jalawure through jalawure cultivation activities so that the community does not depend on jalawure plants that grow wild/naturally.
Farmer’s perception on climate-related disasters and their impacts to support food farming
Authors: Fanggidae Yudi Riadi , Dermoredjo Saktyanu Kristyantoadi , Estiningtyas Woro
Published: September 2021

Changes and extreme climate events have an impact on and cause vulnerability to the food crop sub-sector. Extreme climatic events that have a significant impact on food farming are floods, drought, and pest/disease. The purpose of this study was to determine farmers’ perceptions of climate-related disasters and their impacts to support food farming. The survey and interviews were conducted in Leles Sub-District, Garut Regency in 2019, with the number of respondents was 28 people, were selected randomly. The results of the analysis showed that the climate-related disasters that occurred were pest/disease (43%), drought (18%) and floods (11%). The impact of extreme climates at the study site was a reduction in yields ranging from 5% to crop failure (puso). According to farmers, climate-related disasters occur as a result of weather factors, broken channels/embankments, excessive upstream water, closed drains, poor drainage and uneven water allocation to each land. The handling of this climate-related disaster by farmers was still limited. Farmers' perceptions, understanding and abilities in managing and anticipating climate disasters are needed in order to reduce the risk of food farming.
Accelerating innovation adoption in the “Tagrinov” program in Bali Province
Authors: Mahaputra I Ketut , Rinaldi Jemy , Arya Nyoman Ngurah , Silitonga Tulus Fernando , Sudarmini Ni Ketut
Published: September 2021

One of the natural resources that has the potential to improve the performance of rural farmers is the use of yards. Various efforts have been made by the Ministry of Agriculture, one of which is the Agricultural Innovation Gardens (Tagrinov), which has been a model for government offices. This research was conducted in Bengkel Village, Buleleng Regency, in October-December 2019. The number of respondents was set at 30 farmers implementing the program. The study aim is to identify the level of group adoption of disseminated technological innovations that are profit-oriented farmer groups. The basic research method is descriptive method, using survey technique. The classification of the level of farmer adoption of the technology is divided into 3 categories (high, medium and low) using intervals. The adoption rate analysis for the herd level used the formula N = SA x IA. Followed by analysis of farm income using the following approach: Pd = TR - TC. The results showed the effectiveness of increasing farmers’ knowledge by 64.68% (quite effective), farmers’ attitudes towards the material increased by 3.86 (good category), group adoption rate by 88.11% (high adoption) and as a whole can provide additional income for farmer groups of Rp.752.556,-/month.
The impact of Covid-19 pandemic on people’s behavior and herbal drink (jamu) processing businesses in Banjarbaru, South Kalimantan
Authors: Lesmayati Susi , Qomariah Retna , Awanis  , Pramudyani Lelya
Published: September 2021

This study aimed to determine and analyze the impact of the Covid-19 pandemic on (1) people's behavior to avoid exposure to the virus with consumed traditional herbal drink (jamu), and (2)jamuprocessing businesses in Banjarbaru City, South Kalimantan. The research location was determined purposively in the centre of traditional herbal drink processing known as Kampung Pejabat, Loktabat Selatan Village, South Banjarbaru District Banjarbaru City. The research was carried out from February to March 2021 and was conducted using a survey method to obtain primary data and supported by secondary data from reports and other sources. The data were analyzed descriptively. The studies showed that (1) Preventive efforts avoid the virus done by the peoples at the beginning of the pandemic until now by consumingjamu. Around 82 – 88% of people consumingjamuthat they bought or made themselves, and they also consuming others in smaller amounts. The peoples already know the benefits ofjamuas herbal medicine because it is a hereditary knowledge. Besides, consumingjamu gendongdoes not require a high cost. (2) there was an increase in volume production ofjamu gendongaround 100% at the beginning of the pandemic compared with production before the pandemic. The R/C ratio ofjamuprocessing is increased from 1,3 to 1,54 it means the pandemic had a positive impact on the jamu processing business.
Study of microfinance farmer to make decision for formal and informal credit
Authors: Hardana Andrean Eka , Pratiwi Destyana Ellingga , Prasetyaningrum Dian Islami , Riyanto Sugeng , Purnomo Mangku
Published: September 2021

The study aimed to identify the microfinance implementation by horticultural farmers and analyze the factors influencing the horticultural farmers’ decision to choose the financial institutions. The research location was carried out in two areas, namely (a) Wonomulyo Village, Poncokusumo Subdistrict, Malang Regency, dan (b) Pacet Village, Pacet Subdistrict, Mojokerto Regency. The sample determination was carried out using the Slovin formula using the proportional stratified sampling method. The total sample was 160 farmers. Descriptive and logistic regression analysis (logit) were used to answer the objective of the study. Formal institutions assigne1d to channel the funds include government banks and private banks. Informal institutions that carried out micro-credit funds were the private sector or institutions from the farmers themselves. The majority of farmers knew that the rate level of formal financing sources was lower, but the administrative procedures were considered problematic. The regression's results showed that the factors influenced the decisions of Horticulture farmers to take micro-finance access, including education, length of business, interest rate, and loan amount.
Pineapple farmer corporation development strategy in Central Lampung District, Indonesia
Authors: Ahmadi Noor Roufiq , Mardiharini Maesti , Indrawanto Chandra
Published: September 2021

Central Lampung is a pineapple production center that supplies fresh pineapples for national demand. On the other hand, Sub-optimal production and marketing, which are still controlled by middlemen, are the main problems in pineapple development. The research aims to identify the potential and needs for innovation, and to formulate a strategy for developing pineapple based on farmer cooperations. The research was conducted from September 2020 in Punggur District, Lampung. Data collection was carried out through a Focus Group Discussion (FGD) and in-depth interviews with local champions. The SWOT approach as well as IFE and EFE analysis have been determine to the best strategy. The results showed that farmers used the Queen variety from 1970, so that, the quality production decreased. The innovations needed are mainly related to cultivation (irrigation, crop rotation, control of pests). The existence of Farmer-Owned Enterprises in collaboration with BUMDES has the potential to be reactivated into a farmer corporation. The IFE and EFE analysis showed that the strategy that needs to be taken is the development strategy (SO strategy). Therefor, Policies that need to be followed is increasing: The role and skills of extension workers; and the role of farmers group or corporation in pineapple production and marketing.
Dissemination of soybean technologies in Jambi
Authors: Izhar Lutfi , Nugroho Hery , Novriati Desy , Yardha  , Salwati
Published: September 2021

Jambi province is included in the soybean belt areas and one of the soybean seed production centres in Sumatra. Fulfilling the soybean production demand of the Jambi region also in surrounding provinces, the seed program is one of the main requirement. This paper aims to provide an overview of the soybean seed production program through innovation technologies and dissemination for Jambi. An action research was carried out from 2016 to 2018 in the Tebo and East Tanjung Jabung regions, involving seven breeding farmers, local governments, research centres and other stakeholders. Activities carried out in the form of demonstrations plot, demonstrations farm, and technical assistance activities. The results showed that more than 100 tons of newly soybean certified seeds (Anjasmoro) were distributed from soybean production areas to other areas in Jambi and to other provinces such as: Riau, West Sumatera, South Sumatera and Aceh). Agronomic data and yield parameters in soybean seed activities from research site were showed minor significant differences compare to farmer practices technologies. Some innovation technologies were introduced i.e. good agricultural practices, and good handling practices for soybean seed farmers. Through this activity, soybean seeds are available throughout the year (2016 up to recent).
Water balance analysis in perennial river flow: case study Pulau Laut, South Kalimantan
Authors: Muhardiono Iman , Sosiawan Hendri , Aprilyanto Anton
Published: September 2021

Water scarcity in dry land region is main problem which need to be solved as long the agricultural activity existed. The common technical way to sustain water is capturing rainfall and runoff and stored locally before they go through to the sea. Channel reservoir is simple water infrastructure or dam which consists of reinforced wall constructed by crossed a river channel to store run off flow and facilitate aquifer recharge. This paper aims to calculate a water balance to quantify the amount of water between the dam and hydrological system. Estimation of water balance is generated from rainfall data by Mock, Penman, and linked by mass conservation method. Volume of water during the dry season was gained consistently by 1964.53 m3 where it was above the minimum operation and the live storage capacity of this reservoir about 2,531 m3 where it was adequate to cover water demand for irrigation purpose. In conclusion, channel reservoir can utilize intermittent river channel to store water and be treated as isolated water storage structures with simple manufacture.
The effect of nitrogen fertilizer on hybrid maize yields under the shade of coconut trees
Authors: Sution  , Hatta Muhammad , Arsjad L.M. Gufroni , Marssinai Rustan
Published: September 2021

The need for maize in West Kalimantan is around 320,000 tonnes per year, most of which is still imported from outside the region. Cultivating the maize under the shade of coconut trees is an alternative to meet the needs of maize in West Kalimantan and hence improvement on the cultivation of maize under the shade of coconut trees should be taken seriously. This study aims to determine the effect of nitrogen (N) fertilizer on the growth and yield of hybrid maize under the shade of coconut trees. The research method used a factorial randomized block design consisting of 2 factors. The first factor is maize variety (Nasa 29, Bima 19, Bima 20, JH 21 and Pioneer 35) and the second factor is nitrogen fertilization (64 kg ha-1, 86.5 kg ha-1, 109 kg ha-1, and 131.5 kg ha-) of N, hence 20 treatment combinations are obtained and repeated 3 times. The results showed that the Nasa 29 variety with N fertilizer of 131.5 kg ha-1produced the highest maize grains yield of 4.8 t ha-1. Therefore the using of Nasa 29 variety with the 131.5 kg ha-1of N fertilizer is recommended for intercropping system under the shade of coconut trees.
Evaluation of nutrient and antioxidant activity on steam blanching ofMoringa oleiferaleaves
Authors: Aditama Ryzal Satria , Sukria Heri Ahmad , Mutia Rita
Published: September 2021

Moringa oleiferais a plant that has high nutritional content. Post-harvest treatment take effect in improving product quality. This study was carried out to evaluate nutrient and antioxidant activity of steam blanched moringa oleifera leaves. Sample of moringa oleifera were prepared where the temperature 80°C in ±5 minutes for the steam blanched. The freshM. oleiferaand steam blanchedM. oleiferaleaves dried at 60°C were analyzed for their proximate, mineral, total phenol, total flavonoid, and antioxidant activity contents. The analysis revealed that steam blanched leaves contained more dry matter, crude protein, crude fat, phenolic total, and flavonoid than unblanched leaves. Therefore, its less fibre and mineral. This study showed steam blanching can serve as alternative post-harvest treatment to increase nutritional value of moringa oleifera leaves.
Polymorphism scanning of HSP90AB1 gene in local Friesian Holstein as molecular marker for heat stress resistance
Authors: Prastowo Sigit , Adzdzakiy M. Mumtaz , Vanessa Rebecca , Pambuko Galih , Purwadi  , Susilowati Ari , Sutarno
Published: September 2021

Heat stress poses major problem in dairy cattle in term of reproduction and milk yield, especially in humid tropical climates. The HSP90AB1 is a gene that plays important role in heat stress response. Scanning its allele and genotype variation could be beneficial for the selection of dairy cattle which able to cope with heat stress effect. This study aimed to identify HSP90AB1 gene polymorphism (SNP g.4338T>C) in Indonesian local Friesian Holstein dairy cattle population. In total 20 cattle were sampled randomly. In this study, AS-PCR was employed to amplify 561 bp of gene fragment, using pair of primer namely CF primer 5-CTGGAGTCACACTGAGGAAC-3, TF primer 5-CTGGAGTCACA CTGAGGAAT-3, F primer 5-CTGGAGTCACACTGAG-3, and R primer 5-TGTTGGAGATCGTCACCTG-3. As the results, allele T and C were observed, and respective frequencies are 0.35 and 0.65. Three genotypes of HSP90AB1 gene were found namely CC, CT, and TT. The respective genotype frequency is 0.1, 0.5, and 0.4. According to Hardy-Weinberg analysis, the population is in equilibrium (P>0.05). It is concluded that CT genotype and T allele are the highest frequency in the sampled population. Further study needs to be performed to associate the genotype and allele variation to productivity trait of local dairy cattle.
A method to enrich experimental datasets by means of numerical simulations in view of classification tasks
Authors: Lombardi Damiano , Raphel Fabien
Published: September 2021

Classification tasks are frequent in many applications in science and engineering. A wide variety of statistical learning methods exist to deal with these problems. However, in many industrial applications, the number of available samples to train and construct a classifier is scarce and this has an impact on the classifications performances. In this work, we consider the case in which some a priori information on the system is available in form of a mathematical model. In particular, a set of numerical simulations of the system can be integrated to the experimental dataset. The main question we address is how to integrate them systematically in order to improve the classification performances. The method proposed is based on Nearest Neighbours and on the notion of Hausdorff distance between sets. Some theoretical results and several numerical studies are proposed.
Magenkarzinom und CRC
Authors: Krome Susanne
Published: September 2021

Kolorektale Karzinome (CRC) stellen mit 1–4 % die häufigsten konkomitanten Tumoren von Magenkarzinomen dar. Deshalb empfehlen Leitlinien bei Erstdiagnosen eines Magenkarzinoms den präoperativen Ausschluss von CRC. Nach der Gastrektomie kamen in der retrospektiven Fall-Kontroll-Studie CRC-Vorläuferläsionen häufiger vor. Gweon et al. schlagen deshalb die Koloskopie als festen Bestandteil auch im Nachsorgeprogramm vor.
Medikamentöse Adipositastherapie – Chancen und Perspektiven
Authors: Lautenbach Anne , Aberle Jens , Meyhöfer Sebastian M. , Meyhöfer Svenja
Published: September 2021

Medikamentöse Therapiestrategien sind dringend erforderlich, um Adipositas-assoziierte Begleiterkrankungen langfristig reduzieren und verhindern zu können. Mit einer Gewichtsabnahme um 10% kann bereits eine Reduktion kardiovaskulärer Endpunkte erreicht werden. Als medikamentöse Therapieoption stehen aktuell in Deutschland der Lipaseinhibitor Orlistat sowie der GLP-1 Rezeptor-Agonist (GLP-1RA) Liraglutid zur medikamentösen Langzeittherapie der Adipositas zur Verfügung. Perspektivisch könnten zukünftig noch weitere Therapieoptionen zur Verfügung stehen, mit denen eine effektive Gewichtsreduktion erzielt werden kann. Semaglutid ist bereits als GLP-1RA zur Therapie des Typ 2 Diabetes zugelassen und zeigt, neben einer effektiven HbA1c-Senkung, eine deutliche Gewichtsreduktion. Im Fokus aktueller Adipositasforschung stehen zudem die Multi-Agonisten auf GLP-1-Basis, die balanziert an Rezeptoren mehrerer gastrointestinaler Peptide binden. So zeigen klinische Studien bspw. mit einem dualen Agonisten aus GLP1 und GIP (Glucose-dependent insulinotropic peptide) vielversprechende Körpergewichts-reduzierende Effekte. Weitere Forschungsansätze medikamentöser Therapieoptionen zur Gewichtsreduktion basieren u. a. auf Glukagon-Analoga, PYY und Amylin, aber auch auf Kombinationstherapien wie Leucin-Metformin-Sildenafil. Neben einer Verringerung der Nahrungsaufnahme werden derzeit zudem Therapieansätze zur Steigerung des Energieumsatzes, z. B. über die Aktivierung des braunen Fettgewebes, intensiv beforscht. In diesem Übersichtsartikel werden aktuelle sowie mögliche zukünftige Therapieoptionen zur Gewichtsreduktion in der Therapie der Adipositas zusammengefasst.
Diagnostik des Prostatakarzinoms
Authors: Krome Susanne
Published: September 2021

Jahrzehnte stand beim Verdacht auf ein Prostatakarzinom die 12-fach-Stanzbiopsie mit dem transrektalen Ultraschall im Zentrum. Damit verbunden sind eine relevante Zahl klinisch insignifikanter Diagnosen und gleichzeitig das Risiko für Untertherapien, wenn höhergradige Karzinome nicht getroffen werden. Mit dem diffusionsgewichteten MRT (DWI) zusammen mit dynamischen kontrastverstärkenden Techniken ist heute eine zielgenaue Biopsie verdächtiger Parenchymveränderungen möglich. Die prospektive PRECISE-Studie bestätigt jetzt die Nichtunterlegenheit dieser Methode gegenüber dem alten Standard. Dabei blieb mehr als einem Drittel der Studienteilnehmer eine Stanzbiopsie erspart. Allerdings hat auch die MRT-basierte Diagnostik ihre Schwächen.
Regionale Deprivation und Merkmale der Krankheit und ihrer Versorgung
bei chronisch-entzündlichen Darmerkrankungen
Authors: Raspe Heiner , Lill Cassandra
Published: September 2021

Hintergrund Regionale Deprivation ist als ökologischer Parameter
eine Komponente der sozialen Determinanten von Gesundheit. Zu ihrer Messung
stehen in Deutschland der „German Index of Multiple Deprivation“
(GIMD) und der „German Index of Socioeconomic Deprivation“
(GISD) zur Verfügung. Chronisch entzündliche Darmerkrankungen
(CED) sind keine häufigen, aber ernste körperliche Erkrankungen
unklarer Ätiologie, mit vergleichsweise frühem Auftreten im
Erwachsenenalter, oft chronisch-behandlungsbedürftigem Verlauf und
unsicherer Prognose. Daten einer kontrollierten Versorgungsstudie erlauben es,
Assoziationen zwischen regio-naler Deprivation und Merkmalen der Krankheit und
ihrer Versorgung zu untersuchen. Wir erwarteten ungünstigere
Krankheitsverhältnisse bei höherer Deprivation.

Methodik Vorgestellt werden deskriptive Zusatzauswertungen (n=530)
der 2016 bis 2019 durchgeführten MERCED-Studie zu Wirksamkeit und Nutzen
einer stationären medizinischen Rehabilitation bei Sozialversicherten
mit einer CED. Analysiert wurden Daten aus der Basisbefragung zu
selbstberichteten Krankheitsmerkmalen, Krankheitsfolgen und
Versorgungsleistungen in ihrem Zusammenhang mit dem Ausmaß regionaler
Deprivation der Wohnregion (Kreisebene).

Ergebnisse Die Zuordnung der Wohnregion der Kranken zu den Quintilen von
GIMD und GISD korrelieren unter rho=0,76 miteinander (gewichtetes
kappa=0,74). Regionale Deprivation zeigt, gemessen mit dem GIMD,
überzufällige Unterschiede allein in den sozialen
Teilhabeeinschränkungen (IMET) und der Zahl der
„Einschränkungstage“. Dabei schildern sich Personen aus
dem niedrigsten Deprivationsquintil als am stärksten
eingeschränkt. Für die Einschränkungstage findet sich
ein irre-guläres Muster. Beim GISD wird eine unsystematische Variation
der gesundheitsbezogenen Lebensqualität (EQ-VAS) statistisch
auffällig. Auch hier berichten Personen mit der geringsten regionalen
Deprivation von einer besonders schlechten Lebensqualität. In einem
Extremgruppenvergleich weisen Personen, die in nach GIMD und GISD stark
deprivierten Regionen leben, günstigere Werte im Krankheitsverlauf beim
IMET und EQ-VAS auf. Auch für Parameter der medizinischen Versorgung
lassen sich keine systematischen Zusammenhänge mit den
Deprivationsindizes darstellen.

Schlussfolgerung Krankheitsmerkmale, Krankheitsfolgen und die medizinische
Versorgung von CED-Kranken zeigen sich weitgehend unabhängig vom
Ausmaß der mit zwei Indizes bestimmten regionalen Deprivation. Die
wenigen auffälligen Unterschiede weisen in eine überraschende
Richtung: Personen aus deprivierten Regionen berichten günstigere
Krankheitsverhältnisse.
Lunge – Interstitielle Lungenerkrankungen in der
Rheumatologie
Authors: Bastian Hans , Krause Andreas
Published: September 2021

Interstitielle Lungenerkrankungen (ILD) gehören zu den
häufigsten Organmanifestationen bei entzündlich-rheumatischen
Systemerkrankungen. Sie können sich bei einer Vielzahl rheumatischer
Erkrankungen manifestieren, insbesondere bei rheumatoider Arthritis,
systemischer Sklerose und idiopathischen inflammatorischen Myopathien. ILD sind
mit einer erhöhten Morbidität und Mortalität assoziiert.
Eine sorgfältige Diagnostik unter Einbeziehung von Klinik, apparativer
und Labordiagnostik ist zur Klassifikation und Risikostratifizierung der
zugrundeliegenden Erkrankung und vorliegenden Lungenbeteiligung unabdingbar.
Auch wenn weiterhin nicht alle ätiologischen und pathogenetischen
Details bekannt sind, haben die letzten Jahre einige Fortschritte in
Verständnis und Management der (CTD-) ILD ergeben.