bluuebunny/crossref_metadata_2025 huggingface dataset:
Gestão de Propriedades Rurais Familiares – teoria e prática
Authors: Bueno Pimentel Andrea Eloisa , Frighetto Resende Siqueira Maisa , Stéphanie de Araújo Graziele
Published: June 2024

O trabalho faz uma reflexão teórica acerca de gestão de propriedades rurais familiares brasileiras a partir da experiência dos autores em pesquisas e trabalhos de extensão. A concepção sobre gestão está embasada na visão menos usual sobre gestão e usada por Henry Mintzberg (2014), acadêmico canadense, que defende que a gestão não pode ser reduzida a um conjunto de técnicas ou fórmulas, mas a uma prática complexa e multifacetada. Conclui-se que, diferentemente do que comumente se diz a respeito da ausência de instrumentos de gestão em propriedades rurais familiares, elas estão presentes de maneira informal, e são usadas em conformidade com o tempo disponível do agricultor e seu foco, que tende a ser a produção agrícola in loco. Tal informalidade não é negativa e nem é feita exclusivamente por agricultores familiares. Outros gestores de outros setores também a fazem. O trabalho também destaca a função social que a agricultura familiar tem no Brasil bem como a necessidade de políticas públicas que de suporte a esses agricultores, cujo universo é bastante heterogêneo.
¡Yo digo que ese era mi destino! Entrevista a Teodora Sarapura
Authors: Rojas Villena Mónica , Sarapura Teodora
Published: June 2024

La vida de Teodora Sarapura, Dorita, es un recorrido que nos invita a conocer y reconocernos en las heridas coloniales que han signado la vida de tantos hombres y mujeres de los pueblos originarios, habitantes ancestrales del territorio de la provincia de Salta. Reconocer las tramas que van tejiendo la historia del autorreconocimiento indígena en la mixtura de identidades que es Salta y cómo desde allí la defensa del territorio surge como la lucha primera, la piedra fundamental para ser comunidad, para ir vislumbrando posibles horizontes en un presente complejo. El sueño que da inicio al relato es el hilo conductor de lo que para ella ha sido un mandato desde el deseo de su padre, pero también desde la voz de sus ancestros.
Exploring of Expressive Art Therapy in Counselling: A Recent Systematic Review
Authors: Abdul Rahman Siti NurulHida , Mahmud Mohd Izwan , Ku Johari Ku Suhaila
Published: June 2024

Objectives: This systematic review aims to identify what themes are found in the study of expressive art therapy and counselling, and to identify and analyse the variety of therapeutic research methods and intervention settings to understand how these factors contribute to effective mental health care and therapeutic practise worldwide. Sometimes meeting the complex emotional needs of clients can require more work than typical counselling strategies. This encourages us to explore how EAT can improve therapeutic outcomes for people struggling with a range of mental health conditions. Design: A thorough and systematic review of the literature, including studies, research and applications of expressive arts therapy in counselling, was conducted using the PRISMA framework. Data source: Advanced techniques and targeted keywords were used to search SCOPUS and the Web of Science database. Following a mixed methods analysis of the resulting primary dataset (n = 20), three overarching themes were identified. Methods of review: The database used by the researcher was from 2020-2023. Based on this search, 20 articles met the specified criteria. Results: The initial conclusions of the study indicate that expressive arts therapy can promote the ongoing exploration and integration of creative and therapeutic approaches into mental health care, demonstrating a methodological approach to understanding and treating adult mental health through broader medical and academic methods.
Modeling the Transmission Dynamics of Maize Foliar Disease in Maize Plants
Authors: Mrope Fadhili , Kigodi Odeli
Published: June 2024

Maize Foliar Disease (MFD) is a significant issue affecting maize crop production globally, leading to substantial losses in both yield and quality. This study formulates and analyzes a mathematical model to understand MFD transmission dynamics in maize plants. We confirm that the model's solutions remain positive for all time $t > 0$. Utilizing the next generation matrix approach, we determine the basic reproduction number ($\mathcal R_0$) and examine the stability of the disease-free equilibrium (DFE). Our findings indicate that the DFE is locally asymptotically stable when $\mathcal R_0$are the most influential parameters affecting $\mathcal R_0$. This implies that MFD control efforts should focus on reducing these rates. Effective strategies include implementing disease-resistant maize varieties and improving crop management practices to lower infection rates. Numerical simulations using MATLAB show that reducing these key parameters can effectively control MFD spread, providing insights into optimal intervention strategies. This study underscores the importance of targeted agricultural practices to mitigate MFD and enhance maize production.
Pioglitazona y su relación con el cáncer de vejiga. Revisión sistemática
Authors: Cruz Brito Marco Alejandro , Cruz Brito Marco Andrés , Cisneros Espín Franklin Fernando , Guerrero-Ortiz Fabricio Byron
Published: July 2024

Description: bladder cancer is a public health problem since it is among the 10 most frequent cancers in men, it is related to multiple risk factors among which Pioglitazone stands out.
Relevance: there is controversy in the results of the different studies regarding the true relationship between Pioglitazone and bladder cancer, since some support its relationship, while in others there is no association.
Conclusions: more studies are still needed to definitively establish the true relationship since the current information is contradictory.
Desafíos en la prevención y tratamiento del cáncer de próstata en México: un llamado a la acción
Authors: Murillo-Zamora Efrén
Published: July 2024

El documento es una Editorial
Un caso clínico de MiNEN: carcinoma neuroendocrino primario de células pequeñas concomitante y carcinoma urotelial papilar de alto grado de la vejiga urinaria. ¿Tumor compuesto o colisión?
Authors: Franco-Buenaventura Daniela , Ortiz-Tenorio Diego Fernando , Cortes Armando , García-Perdomo Herney Andrés
Published: July 2024

Bladder cancer is the tenth most diagnosed cancer worldwide, and urothelial carcinoma is the most common histologic type. On the contrary, small primary cell neuroendocrine carcinoma of the bladder is sporadic and accounts for less than 1% of all bladder tumors. These malignancies can be observed in mixed neuroendocrine/non-neuroendocrine neoplasms (MiNENs), which have been studied more in the gastrointestinal tract and lungs but scarcely in this organ due to their low incidence. There are concerns about the pathogenic connection between these two tumors, and the limited evidence accounts for the lack of consensus regarding prognosis and treatment for these patients; therefore, they may need a multimodal approach. Here, we describe the case of a 63-year-old woman who presented with gross hematuria, weight loss, and hypogastric discomfort for the past five months. An intravesical mass was found, and transurethral resection was performed. The Histopathology revealed a high-grade papillary urothelial carcinoma with an invasive component through muscularis propria of the bladder, so she was taken to radical cystectomy with extended pelvic lymphadenectomy. The final pathology report revealed an accompanying primary small cell neuroendocrine carcinoma intermingled with the urothelial one. She received postoperative adjuvant chemotherapy and finally died six months after surgery.
O Papel do Sistema Imune na Fisiopatologia da Migrânea
Authors: Silva Aline Vitali da , Bello Valéria Aparecida , Frederico Regina Célia Poli , Oliveira Carlos Eduardo Coral de , Antonucci Adriano Torres , Reiche Edna Maria Vissoci , Simão Andréa Name Colado
Published: July 2024

A migrânea é uma doença caracterizada por episódios repetidos de cefaleia que são mediados pela ativação trigeminal e liberação do peptídeo CGRP. Adicionalmente existe uma complexa interação com o sistema imune através da inflamação neurogênica e neuroinflamação, com um desequilíbrio entre a resposta pró-inflamatória e a resposta regulatória. O sistema imune inato atua na migrânea principalmente por meio do aumento das citocinas pró-inflamatórias, com destaque para IL-1β cuja produção pode ocorrer no complexo córtex-meninge em decorrência da depressão cortical alastrante ou no gânglio trigeminal sensibilizado pelo CGRP.  Algumas evidências sugerem também efeito do sistema imune adaptativo Th1 e principalmente Th2 que culmina com a ativação de mastócitos meníngeos. Por outro lado, células T regulatórias estão quantitativamente diminuídas na migrânea e acontecem oscilações dos níveis de IL-10, principal citocina anti-inflamatória. Existem evidências  da atuação do sistema imune na migrânea, no entanto seu efeito ainda é pouco conhecido, com necessidade de investigação adicional.
The diverse use of cannabis derivatives in the treatment of chronic pain
Authors: Ferreira Marques Luís Felipe , Dutra Ana Luiza de Almeida , Zafalon Bruno , Fernandes Etienny de Brito Dias , Pachá Derick Pedrosa , Espíndola Renata Serafim
Published: July 2024

IntroductionChronic pain is a pathology that affects thousands of people annually, resulting from different factors and having different etiologies. Several treatments are available today for it, but some cases are still refractory.ObjectiveThis article seeks to highlight the impacts of using cannabis derivatives as an alternative in the treatment of chronic pain.MethodologyThis is a bibliographic review that used the PubMed and Scopus databases to search for and select articles on the use of cannabis derivatives in the treatment of chronic pain. Only clinical trials, cohort studies, case-control studies, and case reports were selected.Results336 articles were found, after applying the inclusion and exclusion criteria, 7 articles were selected to be analyzed, of which 3 used vaporized formulations, 3 used compounds for oral ingestion and 1 analyzed topical use.ConclusionGood efficiency was observed in the use of cannabis derivatives in the treatment of chronic pain, especially compounds rich in delta-9-tetrahydrocannabidiol (THC).
Prevalência de compulsão em migranosos e sua associação com uso excessivo de analgesia
Authors: Braz Ana Carolina Monteiro , Filho Júlio César Cimino Pereira , Barros Maria Clara Lopes de , Ribeiro Matheus Henrique Vieira , Sousa Matheus Silva , Santos Vinícius Henrique dos , Silva Danilo Jorge , Jurno Mauro Eduardo
Published: July 2024

IntroduçãoA migrânea ou enxaqueca, dentre as diversas formas clínicas das cefaleias, é uma das apresentações mais comuns, acometendo cerca de 15% da população mundial, predominantemente mulheres, causando intenso impacto na qualidade de vida do indivíduo. Com o objetivo de aliviar a fonofobia, fotofobia, vômitos precedidos de náuseas, crises unilaterais, pulsáteis e intensas, seus portadores fazem uso excessivo de analgésicos. O uso excessivo de medicação é um problema crescente que depende de controle e manejo, visto que existe a possibilidade do desenvolvimento de transtornos psíquicos como a compulsão nesses pacientes.ObjetivoAvaliar a presença de comportamento compulsivo em pacientes migranosos, observando diferentes âmbitos dessa prevalência, como sua relação com o uso excessivo ou não de analgésicos. MétodosTrata-se de estudo de corte transversal e descritivo com 117 pacientes de ambos os sexos, maiores de 18 anos. Foram aplicados três questionários: Escala de impulsividade de Barratt (BIS-11); o Inventário de Obsessões e Compulsões (OCI-R) e o MIDAS (Migraine Disability Assessment). Os dados dos questionários aplicados foram transcritos para uma planilha eletrônica e processados em Software SPSS Statistics 22.0. Assumiu-se, em todos os casos, o valor crítico de p de 0,05 para rejeição de hipóteses nulas. ResultadosOs achados sugerem que indivíduos com perfil de uso excessivo de analgésicos apresentam maior tendência a apresentarem sintomas compulsivos e que a gravidade dos sintomas migranosos se configura como outro fator extremamente associado ao uso excessivo de analgésicos.ConclusãoO estudo evidenciou que pacientes migranosos em uso excessivo de analgésicos apresentam uma maior tendência a desenvolver comportamento compulsivo.
Urgent Need for Reform: Addressing the Inadequate Emergency Care for Headache Patients Under the Manchester Triage System
Authors: Valença Marcelo Moraes , Peres Mario Fernando Prieto
Published: July 2024

In the dynamic emergency services environment, the Manchester Triage System (MTS), developed in 1997, is crucial in saving lives and optimizing care. Its global adoption underscores its effectiveness in improving workflows and patient safety by ensuring patients receive timely care based on the severity of their conditions. MTS categorizes patients into five priority levels: 'Immediate,' 'Very Urgent,' 'Urgent,' 'Standard,' and 'Non-urgent,' using 55 flowcharts to guide information collection and analysis. However, challenges remain, particularly in triaging headache patients, who are often miscategorized as 'Less Urgent,' potentially overlooking extreme conditions like intracranial hemorrhage or meningitis. Studies highlight the need for regular review and adjustment of triage criteria to ensure accurate prioritization. Enhancing awareness, training, and clinical guidelines for headache management can improve care quality. Continuous reassessment post-triage is essential to address changing conditions and ensure timely interventions, thereby addressing systemic deficiencies and enhancing emergency care.
Yöneticilerin iletişimci biçimlerinin çalışanların iş tatminleri ve işten ayrılma niyetleri üzerine etkisi
Authors: Kıran Funda , Hanımoglu Bengisu , Çetinkaya Bozkurt Özlem
Published: June 2024

Yöneticilerde olması gereken özellikler arasında iletişim oldukça önemli bir yere sahiptir. Öte yandan kurulması gereken iletişimci biçimi şekli üzerinde fikir birliğine varılmış değildir. Bu doğrultuda hazırlanan çalışmada yöneticilerin çalışanlarına gösterdiği iletişimci biçimlerinin, çalışanların iş tatmini ile işten ayrılma niyeti üzerindeki etkisinin saptanması amaçlanmıştır. Gerçekleştirilen çalışmanın evreni kamu ve özel sektör çalışanları olarak belirlenmiş ve kolayda örneklem yöntemine başvurulmuştur. Verilerin toplanmasında anket tekniğinden yararlanılmıştır. Veri toplama süreci ve eksik ile uç verilerin temizlenmesinin ardından toplam 352 anket analiz kapsamına dâhil edilmiştir. İstatistik paket programları ile gerçekleştirilen analiz sonucunda yöneticinin arkadaş canlısı, ilgili, iletişimci imajı, rahat, açık ve etki bırakan iletişim şekillerinin çalışanların iş tatminini arttırdığı ve işten ayrılma niyetini azalttığı saptanmıştır.
Yükseköğretim öğrencilerinin bilgi edinme, destek ve danışmanlık ihtiyaçları: Gümüşhane ve Bayburt üniversiteleri örneği
Authors: Erakkuş Özgür
Published: June 2024

Bu araştırmada Gümüşhane ve Bayburt üniversitelerinde yükseköğretimlerine devam eden öğrencilerin hangi konularda bilgi edinme, destek ve danışmanlık ihtiyaçlarının olduğu, destek aldıkları kişi ve kurumlardan beklentilerinin tespit edilmesi amaçlanmıştır. Araştırmada nitel araştırma yöntemi kullanılmıştır. Model olarak ise durum çalışması kullanılmıştır. Araştırmanın çalışma grubunu 2018-2019 akademik yılında, Gümüşhane ve Bayburt Üniversitelerinde yüksek öğrenim gören ve tipik durum örneklemesi ile belirlenen 84 üniversite öğrencisi oluşturmaktadır. Araştırmada veri toplama aracı olarak araştırmacı tarafından geliştirilen görüşme formu kullanılmıştır. Elde edilen veriler içerik analizinde tabii tutulmuştur. Araştırma sonuçlarına göre; üniversite öğrencileri tarafından, sağlık sorunları, kişilerarası ilişkiler, okul ve mesleki gelişim gibi destek ihtiyacı duyulan konular belirtilmiştir. Bilgi edinmeye ve desteğe hiçbir ihtiyacı olmadığını belirten katılımcılar da mevcuttur. Katılımcılar yakın çevrelerinden, kurumlardan ve yazılı-görsel materyallerden bilgi edinip destek almaktadırlar. Ayrıca kurumların destek ihtiyacı duyabilecek kesime (öğrencilere) ulaşmada daha aktif olması gerektiğini de belirtilmiştir. Sonuçlar bağlamında; yükseköğretim öğrencilerinin bilgi edinme ve destek ihtiyaçlarının karşılanması için Eğitim Bilimleri, Sosyal Hizmet ve Sosyal Politika disiplinlerinin birikimleri birlikte değerlendirilmesi gerektiği önerileri sunulmuştur.
Creation of a roller bench for motorcycle and power product fatigue strength testing
Authors: Kuz’min A. O. , Meshcheryakov D. E.
Published: June 2024

Introduction (problem statement and relevance). The given paper justifies the relevance and describes the process of creating a roller bench for motorcycle and power product fatigue endurance testing. The purpose of the study is to create a roller bench for motorcycle and power product load-bearing structure fatigue strength testing; to develop individual components of the test bench; to analyze the recorded signals during mode metering and during the process of single roughnesses initialization; to test a solo motorcycle on the test bench.

Methodology and research methods. When designing the test bench, Russian and foreign test procedures for motorcycles and automobiles were studied, as well as different patents, articles and papers.

Scientific novelty and results. In order to determine the main parameters of the future roller bench, motorcycle mode metering was performed so as to assess the bearing structure loading when riding through the proving ground roads with special pavements. Further, the selection of the main bench parameters is justified, such as the range of trail and wheelbase of the object under test, diameters of the rollers and method of their rotation rate measuring, dimensions, geometry and number of obstacles, drive power, etc. A system of motorcycle ballasting and holding on the bench is designed. Potential errors when designing similar test benches are shown, their solutions are suggested. Statistical and spectral analysis of motorcycle loads recorded at the FSUE “NAMI” Testing Center proving ground was performed, and, based thereon, selection of single roughnesses for bench testing was made.

Practical significance. As a result of the conducted research, a roller bench, on which a motorcycle is currently being tested, was designed and manufactured. A foundation has been laid for methodical transition from road load tests to bench tests.
Method of determination of parameters of heat exchangers of axial flux electric motors for electric vehicles
Authors: Biksaleev R. Sh. , Grachev E. V. , Osipov V. S. , Karpukhin K. E.
Published: June 2024

Introduction (problem statement and relevance). With the high competition for specific parameters, electrified vehicle manufacturers are making great efforts to create powerful and compact components. One of such solutions is the axial flux electric motor, the specific power of which is claimed by many companies to be over 6 kW/kg. Developments of such top companies as Whylot, YASA, AVID, Beyond Motors, Phi-Power only confirm the promising potential of this research trend.

The purpose of the study is to investigate the thermal state of the axial flux electric motor and determine the heat transfer coefficient of alternative heat exchangers with lower hydraulic resistance.

Methodology and research methods. The methods used are based on the fundamental principles of electronics and electrical engineering, hydrodynamics and heat transfer, methods of research testing and engineering analysis.

Scientific novelty and results. Development of electric motors with high specific power of more that 6 kW/kg is considered to be promising, while cooling remains the main problem. According to the research results, a 3D model of the electric motor heat exchanger is obtained, which most satisfies the given requirements.

Practical significance. Due to continuous increase in power density of this type of electric motors, it is necessary to improve the cooling efficiency. This paper is aimed at solving the issue of determining geometric parameters of the heat exchangers for the electric motors.
FORMATION OF PERSONALITY TRAITS OF ADOLESCENCES IN EDUCATION ENVIRONMENT
Authors: Farajova Narmin
Published: June 2024

The educational environment significantly impacts the formation of personality features in adolescence. Schools can help adolescents develop into well-rounded, resilient, and capable individuals by fostering a supportive, inclusive, and stimulating atmosphere. Effective education policies and practices should consider the holistic development of pupils, addressing not just academic achievement but also social, emotional, and personal growth.
Navigating the crossroads of nursing faculty practice
Authors: Eiswirth Emily , Salib-Barrios Maggie , Sheffey Cassie , Edmison Amy
Published: July 2024

Opportunities and challenges
EXAMINING THE CONTRIBUTIONS OF BRAND IMAGE AND PERCEIVED QUALITY TO CUSTOMER LOYALTY THROUGH SATISFACTION AND TRUST
Authors: Raza Basharat , Sohail Aamir , Sair Shrafat Ali
Published: June 2024

This research aims to evaluate interconnection between brand trust, brand image, customer satisfaction, customer loyalty and perceived quality among 350 reputable brands customers. Thus, study proposes the use of Structural Equation Modeling (SEM) to examine these constructs and their relationship in the context of customer loyalty. The analysis of internal consistency reveals that all constructs are highly reliable with Cronbach’s Alpha values greater than 0.70. Validity analysis, using the Heterotrait-Monotrait Ratio (HTMT), ensures distinctiveness amid constructs. SEM results show significant positive effects: brand trust and brand image both enhance customer satisfaction and loyalty, while the perceived quality positively influences both satisfaction & loyalty. Moreover, customer satisfaction mediates the impact of brand image and perceived quality on customer loyalty. Additionally, the study examines moderating variables, finding that some significantly affect customer loyalty. These findings provide actionable insights for the managers in manufacturing SMEs, emphasizing importance of building brand trust and image, ensuring high perceived quality and fostering the customer satisfaction to cultivate the customer loyalty.
INVESTIGATING THE ASSESSMENT EXPERIENCES OF DISTANCE LEARNERS: A CROSS- SECTIONAL SURVEY
Authors: Tufail Mubeshera
Published: June 2024

The purpose of the study was to analyze assessment experiences of students enrolled in distance education programs. All students enrolled in graduate program were the population for this study. Sample of the study consisted of 518 distance learners selected through stratified random sampling technique. Assessment Experience Questionnaire (AEQ) was used to collect data from students. The results of study were reported in terms of nine sub-constructs of the study. The study concluded a statistically significant difference among students on quantity of effort to do well on the assessment with higher mean score for the students of 3rd semester and male students. The quantity and quality of feedback on the performance was experienced more positively by female students & student who have self-reported about their non-disability. The results provide significant information in order to reach the conclusion & make suitable decision about the research issues. Similarly, some appropriate recommendation have been extracted from the conclusion of study. Therefore, it was recommended to consider the characteristics of distance learners, their needs and experiences to design effective and efficient assessment system for their learning.
CAREGIVER BURDEN: UNDERSTANDING THE EFFECTS OF NATURE’S LOVE AND SALUTOGENESIS IN ELDERLY SPOUSES WITH CHRONIC ILLNESS
Authors: Sohail Aroob , Tariq Shahnila
Published: June 2024

The study was conducted to find relationship between nature, Salutogenesis & caregiver burden in older spouses with chronic illness. It was hypothesized that there is likely to be relationship amid nature, Salutogenesis & caregiver burden in older spouses with chronic illness. It was hypothesized that nature and Salutogenesis are likely to predict caregiver burden in older spouses with chronic illness. The quantitative method was used to collect the data from 120 participants. The Love for Nature Scale (Sohail & Tariq, 2023), Salutogenesis Wellness Promotion Scale (SWPS) (Becker et al., 2015), & Spousal Caregiving Burden Assessing Scale (BAS; Thara et al., 1998) were the respective scales used in this research. This study will offer indigenous basis for researchers to identify links between the relatedness of Love for Nature, Salutogenesis and Spousal Caregiver Burden in the Older adults. Findings showed negative link between nature, Salutogenesis & caregiver burden. Duration of chronic illness negatively predicts caregiver burden whereas seasonal nature & Salutogenesis positively predict caregiver burden. The findings of research are beneficial for the counselling of older adults, especially the ones who are providing care to their spouses.
TO WHAT EXTENT WORKPLACE HAZING AND KNOWLEDGE HIDING WORKS IN ACADEMIA: MEDIATING ROLE OF ETHICAL CONFLICT
Authors: Sarwer Mohsin , Mukhtar Sana , Ramzan Ariba
Published: June 2024

This study aims to investigate impact of moral hazing on knowledge hiding over mediating role of ethical conflict. In this regard, data has been collected from academic institute of Punjab province through cross sectional research design and non-probability convenience sampling technique was used. This study used 400 questionnaires were distributed among participants and out of which 250 were received back. After disposal partially filled & incomplete questionnaires, two hundred and thirty-one were left. These have been used for data analysis purpose. Data was analyzed over descriptive and inferential statistics. Demographic features were analyzed through descriptive statistics while inferential statistics has been used to draw inference over correlation & regression. Results shows that the moral hazing increases knowledge hiding. Similarly ethical conflict increases chances of knowledge hiding. Moreover, ethical conflict is predicted by moral hazing. Moreover, it has been proved that ethical conflict mediates the relationship of moral hazing and knowledge hiding. From practical perspective this study will provide guidelines to the practitioners regarding role of hazing in predicting knowledge hiding. Also, this study will help to devise the policies to control knowledge hiding within the academia.
COMPARATIVE DATA ANALYSIS OF PHYSICAL ACTIVITIES & SPORTS BETWEEN PHYSICAL EDUCATION STUDENTS
Authors: Manzoor Mehwish , Rizwan Muhammad , Khadim Iqra
Published: June 2024

The Daily performance of sports and Physical Activity for health have many of healthy benefits in our lives. Physical activity & sports through puberty affect for physical fitness levels and body composition. The physical activities were compared like the flexibility, common endurance, long jump & speed. Basically research revolve that the regulars have more endurances as parallel to Irregulars. This study also found that the flexibility, general endurance & speed was good in regular as compare to irregular physical activity. Students who are involved in physical activities are expected to be fit physically and can continue healthy physical appearances that is basic key towards healthy lifestyle. This study is based on physical education degree college’s students of northern Punjab, Pakistan. In northern Punjab, there is 112 male colleges where 21 colleges were selected wherein 210 regular & irregular participants were collected. Total number of regulars were 210 and Irregulars were 210. Mean percentage of regulars is 11.04 with SD 10.583 & mean score percentage of Irregulars is 6.92 with SD 10.234. Results offer significant information to reach conclusion.
Manifestaciones hepáticas en niños con fibrosis quística y uso de moduladores CFTR. ¿Qué debemos monitorizar?
Authors: Godoy Peña Marcela , Lina Boza María
Published: June 2024

La enfermedad hepática relacionada con fibrosis quística se observa en el 10% de las personas portadoras de la enfermedad. La terapia con moduladores ha mejorado la morbimortalidad, pero teniendo en cuenta que presentan efectos secundarios infrecuentes es necesario monitorizar. Se analiza el algoritmo propuesto por Eldredge et al, que sugiere las decisiones a tomar basado en el resultado de perfil hepático y su aplicación en la práctica clínica.
Implementasi Algoritma Apriori Pada Penjualan Makanan Ringan dan Minuman Kesehatan
Authors: Pirman Arif , Hanifa Annisa , Triyono Gandung
Published: July 2024

Penjualan merupakan hasil yang sangat diharapkan oleh pengusaha yang bergerak dibidang penjualan. Data transaksi penjualan yang dihasilkan perhari yang hanya disimpan akan membuat ruang penyimpanan menjadi besar. Berdasarkan informasi yang diperoleh dari manager outlet yang berasal dari laporan penjualan bulanan, diketahui bahwa penjualan bulan Desember 2022 sebesar Rp. 28.624.274 dan penjualan bulan November 2022 sebesar Rp. 32.916.104. Dari penjualan tersebut terlihat terjadi penurunan penjualan sebesar 13% pada bulan Desember 2022 terhadap penjualan bulan November 2022. Kondisi ini akan menyebabkan kerugian usaha bahkan jika dibiarkan akan menyebabkan penutupan usaha. Untuk Meningkatkan kembali penjualan maka manajemen   memerlukan pengetahuan atas produk yang dijualnya dan pengetahuan atas pola penjualan yang biasa dibeli oleh konsumen. Dari pengetahuan tersebut maka manajemen dapat mengambil keputusan terkait strategi penjualan yang akan dijalankannya. Untuk memanfaatkan data penjualan yang ada, maka pengolahan data mining dengan analisis asosiasi dapat digunakan untuk mencari produk yang sering dibeli oleh konsumen. Dengan menggunakan algoritma Apriori pada proses analisis asosiasi dapat memberikan informasi produk yang sering dibeli bersamaan, syarat penetapan minimum support sebesar 30% dan minimum confidence sebesar 70%. Dari penelitian yang dilakukan, dihasilkan 8 produk yang saling keterikatan dengan hasil support sebesar 0.333 dan nilai confidence sebesar 71.4%. Hasil penelitian ini dapat dijadikan strategi penjualan untuk meningkatkan penjualan harian.
Analisis Penilaian Kinerja Pekerja Building Maintenance Menggunakan Metode Klasifikasi Dengan Algoritma Decision Tree
Authors: Capah Dwi Ade Handayani , Gerryco Muda Siam Trapsilo  , Nevia Andita Wulandari  , Yunita Rahayu Apriani
Published: July 2024

Dalam pemeliharaan bangunan, kegagalan memahami kondisi ketidakpastian dapat berpotensi menimbulkan risiko yang akan mempengaruhi tujuan proyek konstruksi yaitu, pada biaya yang optimal namun dengan kualitas yang sesuai terhadap konsep dan spesifikasi proyek yang diinginkan serta waktu pelaksanaan yang tepat. Kualitas hasil pekerja yang melaksanakan tugas dan tanggung jawabnya dapat dilakukan penilaian kinerja pekerja. PT Harewa merupakan perusahaan yang bergerak di bidang jasa building maintenance. Penelitian ini untuk menganalisis data penilaian kinerja pekerja building maintenance menggunakan metode klasifikasi dengan algoritma Decision Tree bertujuan untuk mengetahui aspek variable dalam meningkatkan kinerja pekerja building maintenance sehingga memberikan hasil keputusan analisis data penilaian kinerja pekerja dengan pemanfaatan algoritma Decision Tree. Performance accuracy dalam pengoptimalisasi pemodelan kinerja klasifikasi algoritma Decision Tree mendapati nilai accuracy sebesar 77.50%, Precision tertinggi 82.28%, dan recall tertinggi 83.33%. Hasil performance algoritma Decision Tree dapat dimanfaatkan sebagai keputusan peningkatan kinerja pekerja, karena hasil performance accuracy, precision, dan recall membuktikan nilai rata-rata diatas 50%. Dengan demikian, pemanfaatan algoritma Decision Tree dapat membuat hasil keputusan analisis data penilaian kinerja pekerja building maintenance sebagai penunjang peningkatan kinerja pekerja building maintenance dalam kualitas pengerjaan building maintenance yang akan mendatang.
Perancangan Model Sistem Pendukung Keputusan Untuk Menentukan Formasi CASN Menggunakan Naïve Bayes dan Simple Additive Weighting
Authors: Cesar Wahyu , Riki Ramdani Saputra  , Gandung Triyono
Published: July 2024

Di era reformasi birokrasi, pengelolaan manajemen Aparatur Sipil Negara (ASN) menjadi satu hal penting karena dapat mendorong efisiensi anggaran serta memaksimalkan kinerja dan layanan pemerintah. Salah satu penyebab belum optimalnya kinerja ASN hingga saat ini yaitu belum tepatnya penempatan formasi penerimaan pegawai CASN yang disebabkan belum adanya sistem pendukung keputusan yang digunakan oleh biro kepegawaian pada instansi pemerintah pada saat menentukan formasi CASN berdasarkan pada analisa kebutuhan pegawai dari setiap unit kerja. Oleh sebab itu kebijakan pemerintah melalui Surat kementrian PANRB Nomor: B-2156/M.PAN.RB/5/2014 terkait optimalisasi kebutuhan ASN, diperlukan analisa penyusunan kebutuhan formasi CASN dari setiap instansi pemerintah menggunakan e-Formasi. Dalam mendukung kebijakan pemerintah tersebut, tujuan penelitian ini adalah membuat model sistem pendukung keputusan untuk membantu instansi pemerintah dalam menganalisa kebutuhan formasi CASN dengan metode Naïve Bayes Classifier dan Simple Additive Weighting (SAW). Model algoritma Naïve Bayes Classifier yang menghasilkan nilai akurasi 94,44%. SAW digunakan untuk meranking unit kerja prioritas yang sangat membutuhkan formasi pegawai. Hasil penelitian ini dari sebuah model sistem pendukung keputusan dengan kombinasi algortima Naïve Bayes dan SAW didapatkan kelas dan alternatif A7, A8, A9, A4, dan A6 yang merupakan top 5 unit kerja prioritas yang paling membutuhkan pegawai CASN.
Perancangan UI/UX Sistem Informasi Dosen (SIM-DOS Piksi Ganesha) Menggunakan Metode Design Thinking
Authors: Nurhasanah Amalina , Kusumadiarti Rini Suwartika
Published: July 2024

Politeknik Piksi Ganesha memiliki beberapa sistem yang dapat digunakan dalam mempermudah kegiatan akademik, salah satunya adalah akses terhadap Sistem Informasi Manajemen Dosen (SIM-DOS). Website SIM-DOS merupakan aplikasi sistem informasi yang diakses secara online oleh Dosen aktif Piksi Ganesha dalam membantu para dosen melakukan pengelolaan data diri terkait Tridharma Perguruan Tinggi antara lain: Pendidikan, Penelitian dan Pengabdian Masyarakat (Abdimas). Penelitian ini menggunakan metode Design Thinking yaitu: Empathize, Define, Ideate, Prototype dan Test sebagai kerangka kerja dalam menyusun atau menyelesaikan masalah dalam penelitian. Implementasi Design Thinking pada UI/UX SIM-DOS memanfaatkan karakteristik pengguna melalui tool User Persona dan pengujian menggunakan Usability Testing. Perancangan design antarmuka (interface) menggunakan Figma. Secara keseluruhan rancangan UI/UX pada penelitian ini digunakan untuk meminimalisir permasalahan sistem SIM-DOS yang sedang berjalan dalam menunjang kebutuhan para dosen melalui sistem desain antarmuka yang ideal. Design thinking yang diimplementasikan dalam SIM-DOS ini diharapkan dapat mengindetifikasi masalah dan kekurangan beberapa fitur dengan cepat sehingga dapat menjadi rekomendasi bagi developer dalam pengembangan sistem website SIM-DOS menjadi lebih baik. Prototype dari design yang telah dirancang dalam mengetahui perilaku user pengguna aplikasi SIM-DOS dimulai dari mendaftar dan membuat akun baru hingga melakukan unggah pada dokumen dan capaian luaran berhasil dirancang dengan kemudahan-kemudahan pada fiturnya.
Efektivitas Facebook Sebagai Media Marketing Menggunakan Konsep Advertising Balance Scorecard (ABSC)
Authors: Retnawati Lestari , Saurina Nia , Pratama Firman Hadi Sukma
Published: July 2024

Sosial media memiliki peran yang unik dalam mendukung strategi pemasaran. Salah satu platform sosial yang sangat populer untuk mendukung upaya pemasaran adalah Facebook. Kehadiran Facebook Ads telah mendorong banyak perusahaan untuk mengalokasikan sebagian besar anggaran pemasaran mereka untuk beriklan di platform tersebut. Dengan potensi terus berkembangnya pemasangan iklan di Facebook, baik melalui model iklan sederhana maupun melalui opsi canggih seperti Facebook Ads, penting untuk memahami seberapa efektif platform ini bagi bisnis. Penelitian ini bertujuan untuk mengetahui efektivitas Facebook sebagai media marketing menggunakan konseo ABSC. Studi ini menggunakan pendekatan survei. Partisipasi penelitian ini sebanyak 100 responden. Penelitian ini menggunakan Advertising Balance Scorecard (ABSC) sebagai alat untuk mengukur efektivitas iklan di Facebook. Hasil penelitian menunjukkan bahwa nilai efektivitas iklan sebesar 4,31, reliabilitas Facebook sebagai platform pemasaran mencapai 4,38. Hal ini menegaskan bahwa Facebook efektif digunakan sebagai sarana pemasaran, terutama dalam konteks memasarkan produk fashion. Disarankan penelitian lebih lanjut pada platform media sosial lainnya, serta membandingkan efektivitas pemasaran melalui berbagai platform.
UJI SENSITIVITAS BAKTERI Escherichia coli TERHADAP ANTIBIOTIK PADA URIN PASIEN INFEKSI SALURAN KEMIH DI LABORATORIUM KLINIK BUNDA THAMRIN MEDAN
Authors: Rajagukguk Tiara , Siahaan Maniur Arianto , Aritonang Erlan
Published: July 2024

Urinary tract infection disease is one of the most common health problems in the community, and the most common pathogenic cause is Escherichia coli bacteria. The purpose of this study was to determine the sensitivity of Escherichia coli bacteria to antibiotics in the urine of patients with urinary tract infections (UTI) at the Bunda Thamrin Clinical Laboratory. This research was conducted from March to May 2024 starting from literature search to writing research reports. The population in this study were all patients with UTI in March to May 2024 and the samples used were 10 samples. This study used two types of antibiotics, namely ciprofloxacin and gentamicin antibiotics. The method used in this study is the Escherichia coli examination method by culturing on Mac Concey Agar media and sensitivity testing using the Vitek 2 Compact tool. The results of the bacterial identification test showed that there was growth of Escherichia coli bacteria and Klebsiella sp. The results of the sensitivity test of Escherichia coli bacteria to antibiotics showed that Escherichia coli bacteria were still sensitive to gentamicin antibiotics by 75% and resistant by 25%. Antibiotic ciprofloxacin was resistant by 87.5% and intermediate by 12.5%.
THE BASE PRESENCE AT THE ALKYLSULFOCHLORINATION OF β-AMINOPROPIOAMIDOXIMES IN CHLOROFORM AND WATER
Authors: Kayukova L.A. ,   A.B. Bekturov Institute of Chemical Sciences JSC, Vologzhanina A.V. , Yerlanuly A. , Duisenali A.M. ,   A.N. Nesmeyanov Institute of Organoelement Compounds,   A.B. Bekturov Institute of Chemical Sciences JSC,   A.B. Bekturov Institute of Chemical Sciences JSC
Published: July 2024

We have studied the regioselectivity of alkylsulfochlorination of β-(4-phenylpiperazin-1-yl)- and β-(benzimidazol-1-yl)-propioamidoximes using AlkSO2Cl under two conditions: (i) in chloroform in the presence of tributylamine (Bu3N) as a base at room temperature (r.t.); (ii) in water and acetone (4:1) without Bu3N at r.t. The reaction under the conditions (i) leads to the return of the original amidoximes, the formation of 2-amino-8-phenyl-1,5,8-triazaspiro[4.5]dec-1-ene-5-ammonium chloride and β-(benzimidazole-1-yl)propioamidoxime hydrochloride. When alkylsulfochlorination occurs under conditions (ii): β-(4-phenylpiperazin-1-yl)propioamidoxime reacts with iso-propylsulfonyl chloride and β-(benzimidazol-1-yl)propioamidoxime ‒ with methylsulfonyl chloride, 2-amino-8-phenyl-1,5,8-triazaspiro[4.5]dec-1-ene-5-ammonium hydrochloride, iso-propylsulfonate and O-methylsulfonyl-β-(benzimidazol-1-yl)propioamidoxime hydrochloride were obtained in quantitative yields. Thus, under conditions (i) Bu3N binds alkylsulfochlorides into alkylsulfonyltributylammonium chlorides and the alkylsulfochlorination products of β-aminopropioamidoximes were not formed; under conditions (ii) alkylsulfochlorination products were isolated: 2-amino-8-phenyl-1,5,8-triazaspiro[4.5]dec-1-ene-5-ammonium iso- hydrochloride, propylsulfonate and O-methylsulfonyl-β-(benzimidazole-1-yl)propioamidoxime hydrochloride.
STABILIZING ADDITIVE FOR CRUSHED STONE-MASTIC ASPHALT CONCRETE BASED ON A LOW-GRADE PRODUCT AND WASTE FROM THE PRODUCTION OF CHRYSOTILE ASBESTOS
Authors: T.Arynov K. ,   Institute of Innovative Research and Technology, Aueshov A.P. , Berikova U. , Alzhanov K.B. , Tazhayak A.E. ,   M.Auezov South Kazakhstan University,   Institute of Innovative Research and Technology,   M.Auezov South Kazakhstan University,   Institute of Innovative Research and Technology
Published: July 2024

The results of a study of adsorption activity for bitumen and the physical and mechanical characteristics of the additive for crushed stone-mastic asphalt concrete (SMA), made on the basis of low-grade chrysotile and dusty waste from the enrichment of chrysotile-asbestos production, are presented. Structuring of the surface of layered magnesium silicates 3MgO 2SiO2 2H2O by treatment with dilute solutions of mineral acids is proposed, in which magnesium dissolution occurs only from the surface layers of magnesium silicate. At the same time, due to the structural features of the tubular structure - multilayering, the initially fibrous structure of magnesium hydrosilicate is preserved, and a layer enriched with silicon is formed on the surface of the fibers. As a result, the surface acquires a more amorphous state, which causes an increase in adsorption activity for bitumen. Based on the results of establishing the physical and mechanical characteristics of an additive made from low-grade chrysotile and powdered waste chrysotile-asbestos in the prepared crushed stone-mastic asphalt concrete mixture (ShchMAS-20), it is shown that the selected composition meets all the requirements of GOST 31015-2002 “Asphalt concrete mixtures and crushed stone asphalt concrete - mastic. Technical conditions".
Actividad antitumoral de complejos de cobre(II) con fenantrolina y dipéptidos en células de cáncer de mama
Authors: Muñoz Garzón Katherine Seneth , Álvarez Natalia , Facchin Gianella , Soria Beatriz D. , Di Virgilio Ana Laura
Published: July 2024

The search for non-toxic anti-cancer therapies has increased, allowing the development of new metal complexes linked to essential molecules such as amino acids. For this reason, two copper(II) compounds were studied with a main ligand such as 1,10 phenanthroline (phen). The complex [CuCl2(phen)] (1) was studied in comparison to the ternary complex with a dipeptide (the result of the union of two amino acids such as alanine and phenylalanine as an auxiliary ligand) [Cu(L-Ala-Phe) (phen)]·4 H2O (2) in the human breast cancer cell line MCF-7. Functional analysis showed that both complexes induce antiproliferative and an effect on clone inhibition; Anyway, neither of the two complexes showed an increase in the production of EROs. On the other hand, the phenomenon of cell death induced by 1 occurs through the necrosis process, while 2 causes the induction of early apoptosis. Likewise, only at low concentrations of 2 (1 μM), we found double and single-strand DNA breaks, which suggests that it could be one of the molecular targets related to its antitumor activity. This compound is a promising candidate for further in vivo studies that prove to be a good alternative therapy for breast cancer.
Entre la normativa nacional y los estándares internacionales: un análisis de la política de cáncer infantil en Colombia
Authors: Caballero Blanco Vìctor Alfonso , Soler Barrera Jenyffer Nathalie
Published: July 2024

Childhood cancer poses a significant public health challenge, prompting the formulation of numerous strategies to address it. Objective: delve into the normative structure of Colombia's childhood cancer policy, seeking points of convergence with the Global Initiative for Childhood Cancer (GICC) developed by the World Health Organization (WHO). Methods: a descriptive analysis of the national policy was conducted, relying on normative reviews and research findings on childhood cancer in Colombia. Results: the study contributes evidence to comprehend the intersections between the national policy and WHO's global approach to tackling childhood cancer. Opportunities for improvement are identified in the implementation of care centers, comprehensive healthcare networks, diagnostic timeliness, treatment regimens, and the recording and monitoring processes. Conclusions: Colombia's national regulations are robust, addressing childhood cancer challenges akin to WHO's technical package. Shared implementation challenges underscore the need for continued collaborative efforts, with a specific emphasis on enhancing the registration and monitoring system as a pivotal step in policy implementation and enhancement.
Agradecimientos evaluadores Vol 11(1) 2024
Authors: Órtiz León Darío
Published: July 2024

La Revista Colombiana de Hematología y Oncología agradece el trabajo de revisión realizado por los evaluadores para esta edición.
NIGERIA-CZECHOSLOVAKIA RELATIONS BEFORE AND AFTER THE SPLIT OF CZECHOSLOVAKIA IN THE 20TH CENTURY AND BEYOND
Authors: Yakubu Suleiman
Published: July 2024

Nigeria-Czechoslovakia relations have been very robust and beneficial to both countries. The relations and interactions between both countries at the beginning of the 20th century were minimal because Nigeria was still under colonial rule but improved after her independence in 1960. This opened doors to a great deal of opportunities for developing long-lasting and broad relations in security, politics, economy, and sociocultural spheres. With the split of Czechoslovakia into the Czech Republic and Slovakia in 1993, relations between Nigeria and the Czech Republic intensified in the areas of commerce and trade, military training, and education, but the relations Nigeria has had with Slovakia over the years have been minimal. This paper aims at discussing and identifying, while using both primary and secondary sources, the key areas where both countries have had relations over the decades and how the relations have impacted both countries in the twentieth century and beyond.
1868-1870 Yılları Arasında Manisalı Kadınların Maddi Varlıkları Üzerine Bir Değerlendirme
Authors: Aydın Özden
Published: July 2024

Arşiv malzemeleri siyasi olayların tarihine ilişkin verdiği aydınlatıcı bilgilerin dışında, insanı ilgilendiren her türlü yaşanmışlığın izlerini önümüze seren yığınla bilgiyle doludur. Bu açıdan bakıldığında Osmanlı toplumsal hayatında kadın faktörünü konu alan kaynaklar içerisinde yer alan tereke kayıtları incelendiği takdirde sosyal ve iktisadi hayatta erkekler kadar aktif olduklarını ortaya koymaktadır. Yine kadınların ön planda yer aldığı, Osmanlı toplumsal ve ahlaki normları çerçevesinde gündemine giren konular arasında yer alan giyim-kuşam fermanları çoğu kez muhafazakâr bir bakış açısıyla kaleme alınmıştır. Bu araştırmamızda Manisa 335 numaralı Şer’iyye Sicilinde 1868-1870 tarihinde yer alan 12 adet kadın terekelerinden yola çıkarak, Manisa’da kadının taşınır ve taşınmaz malları borç ve alacakları, giyim-kuşam ile ev eşyaları hakkında bilgi verilmeye çalışılmıştır. Özellikle Manisa kadınlarının gündelik hayatına ilişkin giyim-kuşam ve ev eşyalarındaki tercih ve eğilimlerinin iktisadi analizleri yapılmaya çalışılacaktır.
Proceedings of the 2024 ICAP Convention
Authors:   International Consortium of Oral Ankylofrenula Professionals
Published: June 2024

The International Consortium of Ankylofrenula Professionals (ICAP) held its 2024 Conference in Cleveland, Ohio, themed "Collaboration Rocks," from May 2 to 4, 2024. The Conference Proceedings includes abstracts and summaries of plenary, concurrent, and poster presentations.