bluuebunny/crossref_metadata_2025 huggingface dataset:
Solução proposta a partir do modelo hélice tríplice para um projeto de biodiesel como potencial propulsor para a economia circular
Authors: Rodrigues Rodrigo , Reis Guimarães Neto Abelino , Franco Gonçalves Rodrigo , Machado Tambor José Humberto
Published: December 2020

A Economia Circular (EC) denota sensível relevância quanto aos efeitos positivos sobre a preservação ambiental e permite criar vantagens competitivas por empresas concomitantes à mesma. Este artigo explora especificamente um método proposto através do modelo hélice tríplice (3H) para a coleta do óleo de cozinha usado (óleo) em pontos específicos como feiras livres, Bom Prato - programa de segurança alimentar brasileiro criado no estado de São Paulo -, Comedoria - espaços de alimentação do Serviço Social do Comércio (SESC) –, praças de alimentação situados em Instituições de Ensino (IE), espaços de entretenimento, entre outros eventos realizados no munícipio de Guarulhos - SP. A transformação do óleo em biodiesel associada a recursos de tecnologia como geolocalização e leitura de Tags - em tradução livre para o português: etiquetas - para Identificação por Radiofrequência (RFID, do inglês Radio Frequency Identification), permite o reabastecimento de transportes para coleta de resíduos, bem como de geradores de energia a diesel baseados numa perspectiva de desenvolvimento sustentável.
Vibration research of heavy trucks. Part 2: Optimization of vehicle dynamic parameters
Authors: Ye Yong , Nguyen Vanliem , Hu Yongzhu
Published: December 2020

In order to enhance the ride comfort, stability, and safety of heavy trucks. Based on the dynamic characteristics of the parameters of heavy trucks and its dynamic model, a multi-objective genetic algorithm are developed in the MATLAB environment and applied to optimize the dynamic parameters of vehicles. The weighted root-mean-square (RMS) accelerations of the cab and driver seat vibrations are chosen as the study goals to evaluate the results under different vehicle conditions. The obtained results show that the optimal parameters of vehicles are significantly enhanced the vehicle ride comfort under different operation conditions. Particularly, the weighted RMS accelerations of the awz and awφc are significantly reduced by 26.3 % and 35.3 % under the ISO level B of the road surface, and a vehicle speed region from 17.5 m/s to 20 m/s (63 km/h to 72 km/h).
Programas televisivos e suas estruturas narrativas: enredo, personagens, tempo, espaço e foco narrativo em teledramaturgia e entretenimento
Authors: Hergesel João Paulo
Published: December 2020

This text, whose discursive dimension transits between the academic essay and the theoretical manual, reflects on an interdisciplinary methodological procedure that derives from Literature, but which can be applied in analyses of audiovisual products, especially television works. The aim is to revisit the notions of plot, characters, time, space and narrative focus – so dear to structuralism – and propose their observation in television programs, especially in theater and entertainment. The methodology encompasses a bibliographic and interpretative study of categories of Narratology, a discipline that orbits between Letters and Communication. The results point out that the ideas that were in vogue in the 1970s are still useful for understanding phenomena of mass culture in their contemporary narratives.
Comparative Analysis of Risk Stratification Scores in Atrial Fibrillation
Authors: Samaras Athanasios , Doundoulakis Ioannis , Antza Christina , Zafeiropoulos Stefanos , Farmakis Ioannis , Tzikas Apostolos
Published: December 2020

Background:

Atrial Fibrillation (AF) has become a major global health concern and is associated
with an increased risk of poor outcomes. Identifying risk factors in patients with AF can be challenging, given
the high burden of comorbidities in these patients. Risk stratification schemes appear to facilitate accurate prediction
of outcomes and assist therapeutic management decisions.

Objective:

To summarize current evidence on risk stratification scores for patients with AF.

Results:

Traditional risk models rely heavily on demographics and comorbidities, while newer tools have been
gradually focusing on novel biomarkers and diagnostic imaging to facilitate more personalized risk assessment.
Several studies have been conducted to compare existing risk schemes and identify specific patient populations
in which the prognostic ability of each scheme excels. However, current guidelines do not appear to encourage
the implementation of risk models in clinical practice, as they have not incorporated new ones in their recommendations
for the management of patients with AF for almost a decade.

Conclusion:

Further work is warranted to analyze new reliable risk stratification schemes and optimally implement
them into routine clinical life.
Recent Advances in C–H Activation and Functionalization of Quinazolinones/ Quinazolines
Authors: Umadevi N. , Kumar G. , Reddy N.C. Gangi , Reddy B.V. Subba
Published: December 2020

This review summarizes the transition metal-catalyzed direct C–H functionalization
of quinazolinones and quinazolines through C-C, C-N and C-O bond formations. It focuses
mainly on the C-H (sp2 or sp3) bond arylation, amination, sulfamidation, acetoxylation,
halogenation, annulation of quinazolinones and quinazolines. This review illustrates the scope
of C-H activation and functionalization of various quinazolinone and quinazoline derivatives.
Aging of Brain Related with Mitochondrial Dysfunctions
Authors: Dhote Vipin , Samundre Prem , Ganeshpurkar Aditya , Upaganlawar Aman
Published: December 2020

Advancing age presents a major challenge for the elderly population in terms of quality
of life. The risk of cognitive impairment, motor in-coordination, and behavioral inconsistency due
to neuronal damage is relatively higher in aging individuals of society. The brain, through its structural
and functional integrity, regulates vital physiological events; however, the susceptibility of
the brain to aging-related disturbances signals the onset of neurodegenerative diseases. Mitochondrial
dysfunctions impair bioenergetic mechanism, synaptic plasticity, and calcium homeostasis in
the brain, thus sufficiently implying mitochondria as a prime causal factor in accelerating aging-related
neurodegeneration. We have reviewed the fundamental functions of mitochondria in a
healthy brain and aimed to address the key issues in aging-related diseases by asking: 1) What goes
wrong with mitochondria in the aging brain? 2) What are the implications of mitochondrial damage
on motor functions and psychiatric symptoms? 3) How environmental chemicals and metabolic
morbidities affect mitochondrial functions? Further, we share insights on opportunities and pitfalls
in drug discovery approaches targeting mitochondria to slow down the progression of aging and related
neurodegenerative diseases.
A Combined Method of Protein Extraction from Unorthodox Plant Samples for Proteomics
Authors: Yilmaz Can , Iscan Mesude
Published: December 2020

Aim:

This study aimed to generate an improved method of protein extraction and purification
from plant tissues containing very high amounts of phenolic compounds and other interfering
biomolecules.

Background:

Protein extraction at proteomic studies on some plant species, including conifers, is
challenging, and the yield and quality are unpredictable.

Objective:

Two popular protocols were combined with each other to construct a novel one with enhanced
abilities to produce higher purity of samples compatible for high precision molecular systems
and analysis.

Method:

The new method was compared with the other two for their efficiencies in classical SDS-
PAGE, 2-DE and capillary chromatography applications.

Results:

All three methods were comparable in SDS-PAGE procedure; however, only the new
method created acceptable gel images in 2-DE. Bioanalyzer results, also, demonstrated that the
new method provided protein samples pure enough to be used in capillary chromatography with 2
times more peaks in electropherograms with lower noise and higher total relative protein concentrations
closest to the applied amount.

Conclusion:

The new combined method is a successful alternative for plant proteomicists with
higher yield and quality of proteins from recalcitrant tissues.

Other:

The new method could be preferred, especially, for high-tech, sensitive proteomic analysis.
Anti-Hypertensive Potential and Epigenetics of Angiotensin II type 2 Receptor (AT2R)
Authors: Chaudhary Mayank
Published: December 2020

Background::

Renin angiotensin system (RAS) is a critical pathway involved in blood pressure regulation. Octapeptide, angiotensin II (Ang II), is a biologically active compound of RAS pathway which mediates its action by binding to either angiotensin II type 1 receptor (AT1R) or angiotensin II type 2 receptor (AT2R). Binding of Ang II to AT1R facilitates blood pressure regulation, whereas AT2R is primarily involved in wound healing and tissue remodeling.

Objective::

Recent studies have highlighted additional role of AT2R to counter balance detrimental effects of AT1R. Activation of angiotensin II type 2 receptor using AT2R agonist has shown effect on natriuresis and release of nitric oxide. Additionally, AT2R activation has been found to inhibit angiotensin converting enzyme (ACE) and enhance angiotensin receptor blocker (ARB) activity. These findings highlight the potential of AT2R as novel therapeutic target against hypertension.

Conclusion::

The potential role of AT2R highlights the importance of exploring additional mechanisms that might be crucial for AT2R expression. Epigenetic mechanisms, including DNA methylation and histone modification, have been explored vastly with relation to cancer, but the role of such mechanisms in the expression of AT2R has recently gained interest.
Nonalcoholic Fatty Liver Disease (NAFLD) for Primary Care Providers: Beyond the Liver
Authors: Godinez-Leiva Eddison , Bril Fernando
Published: December 2020

Nonalcoholic fatty liver disease (NAFLD) has consolidated as a major public health
problem, affecting ~25% of the global population. This percentage is significantly higher in the setting
of obesity and/or type 2 diabetes. The presence of NAFLD is associated with severe liver complications,
such as nonalcoholic steatohepatitis (NASH; i.e., presence of inflammation and necrosis),
cirrhosis and hepatocellular carcinoma. However, the majority of these patients die of cardiovascular
disease. For this reason, management of this condition requires a multidisciplinary team,
where primary care providers are at center stage. However, important misconceptions remain
among primary care providers, preventing them from appropriately approach these patients. Nonalcoholic
fatty liver disease should be understood as part of a systemic disease characterized for abnormal
accumulation of fat in tissues other than the adipose tissue. This, in turn, produces dysfunction
of those organs or tissues (process sometimes referred to as lipotoxicity). Therefore, due to the
systemic nature of this condition, it should not surprise that NAFLD is closely related to other
metabolic conditions. This review will focus on the extrahepatic manifestations of NAFLD and its
metabolic and cardiovascular implications. We believe these are the most important issues primary
care providers should understand in order to effectively manage these complicated patients. In addition,
we have provided a simple and straightforward approach to the diagnosis and treatment of patients
with NAFLD and/or NASH. We hope this review will serve as a guide for primary care
providers to approach their patients with NAFLD.
Development and Innovation on Dental Products in Argentina: A Technological Prospecting Based on Patents
Authors: Valadas Lidia Audrey Rocha , de Oliveira Filho Rosueti Diogenes , Lotif Mara Assef Leitão , Josimar Girão Francisco , de-Alencar Emmanuel Arraes , Bandeira Mary Anne Medeiros , Squassi Aldo
Published: December 2020

Background::

Argentina has progressed with industrialization in comparison
to other Latin American countries and this process had a direct impact on the innovative
capacity of the national economy. A constant search for market leadership, including the
dentistry field and dental materials, stimulates the industries to launch new products daily.
Inventions related to health researches are mostly protected by patents as intellectual
property. A patent landscape analysis through searches in patent banks is a tool used to
identify trends in different areas of innovations.

Objective::

This study aims to identify and evaluate the scenario of research, development
and innovation of dental products in Argentina by a technological prospecting based on
patents.

Methods::

A survey of patent documents was conducted by searching for deposited and
granted patents of dental products. The search was carried out during January 2020 in the
patent database of the National Institute of Industrial Property of Argentina (INPI-AR).
The terms “dentistry”, “buccal”, “dental” and “oral” were used to select the titles and abstracts
of patent application reports. The information extracted from patent reports was organized
in tables and Figs using Fig.Pad Prism 6 software to evaluate the applications.

Results::

A total of 363 patents were published from 1989 to 2016, mainly by international
industries, 93.3% as patent invention and 3.0% as utility model applications on dentistry.
Only two patents (0.5%) were deposited by universities, as the University of Melbourne
(Patent number 20060102378) and Universidad Nacional del Nordeste (Patent
number 20140104149), among which only the last one is national. Among the deposits,
only 6.6% were granted; mostly were in force, denied or lost. According to the specialties,
most patents were related to compositions (64.7%) and personal products (21.7%),
also on dentistry/cariology (6.33%) and prostheses/implants (4.68%).

Conclusion::

In general, we find that most patent applications are related to the preventive
area, personal products and compositions for formulations. Few dental patents deposits
are currently available in Argentina, suggesting that the importation of products into
the area remains large, which can make dental products more expensive. It is important
to invest in technology-based companies to promote increased economic activity, being
a consequence of an investment in knowledge creation and intellectual property to
the Dentistry area.
Melittin: A Natural Peptide with Expanded Therapeutic Applications
Authors: Tiwari Ruchi , Tiwari Gaurav , Lahiri Akanksha , Ramachandran Vadivelan , Rai Awani
Published: December 2020

Background:

Apis mellifera, European honey bee venom (BV) is a complex combination of chemical compounds
comprising proteins, peptides, enzymes, and other small molecules. Melittin (MEL), which is the key component of BV is
considered as an alternative for treatment of various infections. MEL is an amphipathic, cell-penetrating, 26-residue, ahelical anti-hepatoma peptide derived from BV. However, owing to its initial conformational strength and poor stability,
melittin is constrained in use as a medication.

Objective:

The study focused on collective data of therapeutic activities of Bee venom component, MEL.

Method:

Regardless of its broad variety of biological and possible therapeutic uses, there has been increasing concern in
the use of MEL. According to literature, MEL revealed range of activities started from Anti- cancer activity, Anti- microbial
activity, Anti- viral activity, Anti-inflammatory activity to Anti- diabetic activity. Present review article summarized
therapeutic applications of MEL, their mechanism of action along with recent research progress in field of its delivery.

Conclusion:

It could be concluded that MEL exerts multiple effects on cellular functions of infected cells.
Addressing Depression and Suicidality in the College Population
Authors: Alexander Amy W. , Morris Marcia , Chopra Mehak
Published: December 2020

Background:

The need for mental health care among college students has grown exponentially
over the last decades; not only is the number of students needing care greater, but there is a
higher acuity as well. 19.9 million students are estimated to attend college in fall 2019. Relatively
few consensus guidelines exist on college mental health treatment and services.

Objective:

The aim of this study is to review the current understanding of depression and suicidality
in the college population, current treatment methods, and campus-wide systems considerations for
addressing these issues.

Method:

Review of current literature.

Results:

The increasing rates of depression and suicidality in the college student population have resulted
in increased morbidity and mortality, affecting college students and campuses across the country.
A comprehensive approach to address these issues includes treatment at an individual levelincluding
psychopharmacological treatment and various therapies, knowledge of campus and local
community resources, engaging students’ support systems including parents when appropriate, and
campus-wide systems approaches and interventions for reducing depression and increasing ease of
access to mental health services.

Conclusion:

A comprehensive and systems approach is necessary for addressing the increased rates
of depression and suicidality among college students.
Fault Detection in Power Distribution
Authors: Jhajharia Amarjeet , Kumari Uma , Chouhan Nitesh , Meena Yogesh
Published: December 2020

Background :

In the present scenario, electricity theft is a major problem for the government.
This problem affects the Indian economy since GDP goes down due to theft. Electricity is a
part of living and its theft affects the common man who indirectly pays for the theft done by someone
else in the form of extra charges.

Methods:

In this paper, we present a novel identification pattern-based energy fault detector, by leveraging
the customers' normal and faulty line. The target of this paper was to implement a system to
monitor the readings and to find the fault in the power line in real time. Manipulations in readings of
the meter are impossible.

Results:

There is a real time monitoring of meters. Readings could be provided to customers on daily,
weekly, monthly or yearly basis. As soon as there occurs a fault, it could be rectified because
detection is on a real time basis and further messages can be sent to the customer about the fault.

Conclusion:

A comparison of developed real time monitoring system is done with GSM meters and
analog meters.
Cell Wall Components of Bacillus pumilus SE5 Improved the Growth, Digestive and Immunity of Grouper (Epinephelus coioides)
Authors: Yang Hong-Ling , Hu Xi , Ye Ji-Dan , Seerengaraj Vijayaram , Yang Wei , Ai Chun-Xiang , Sun Yun-Zhang
Published: December 2020

Background::

Probiotic cellular components could be an interesting alternative to live
probiotics, which could potentially cause safety problems in open aquatic environments.

Objective::

The cell wall (CW), peptidoglycan (PG) and lipoteichoic (LTA) were extracted from
probiotic strain of Bacillus pumilus SE5, and these biomolecules were used to develop the possible
application in fish aquaculture.

Methods::

Grouper (Epinephelus coioides) juveniles were fed with either a basal control diet or the
basal diet supplemented with CW, PG and LTA respectively for 60 days, and the growth performance,
digestive enzymes activities, serum immune responses and immune genes expression in
head kidney were determined.

Results::

Dietary supplement PG and LTA significantly improved final body weight (FBW), weight
gain rate (WGR), specific growth rate (SGR) and protein efficiency ratio (PER), while significantly
decreased feed conversion ratio (FCR) was noticed in all the treatments compared with the control
group. Dietary supplements of CW, PG and LTA enhanced the activities of trypsin, lipase and amylase
in the liver. Serum complement C3 and IgM levels as well as, AKP, ACP and SOD activities
elevated significantly in fish fed the PG and LTA containing diets. Furthermore, PG and LTA containing
diets, significantly up-regulated expression of TLR2, NOD2, IL-8, IgM and three antibacterial
peptides genes (epinecidin-1, hepcidin-1 and β-defensin) in the head kidney.

Conclusion::

PG and LTA originated from probiotic B. pumilus SE5 could effectively enhance the
growth performance, feed utilization, digestive ability and boost innate and adaptive immune system
of E. coioides.
O pensamento econômico em saúde de Hésio Cordeiro sobre o financiamento da saúde pública no Brasil e a intervenção anticíclica em Claudio Napoleoni
Authors: Carnut Leonardo , Teixeira Glauce Araújo Taborda , Valencia Gabriela Araújo
Published: December 2020

Neste artigo, realiza-se uma reflexão teórica sobre como Hésio Cordeiro, um dos sanitaristas mais influente dos anos de 1980, tratou o problema do financiamento da saúde em sua obra, sob a influência de Claudio Napoleoni. Para isso, usou-se o ensaio como modalidade textual e, como método, a análise de conteúdo. O texto está estruturado em três partes. A primeira descreve uma breve biografia intelectual e político-institucional de Hésio Cordeiro e de Claudio Napoleoni a fim de situá-los historicamente. A segunda versa sobre como Cordeiro foi inspirado por Napoleoni ao analisarmos as soluções anticíclicas para pensar a saúde pública nos anos de 1980. Por último, a terceira aponta uma breve consideração final para valorizarmos a importância de Cordeiro como um intelectual propositor de soluções progressistas para a saúde no seu tempo.
Politics and Power. Notes on Lafont’s Hermeneutics of Democracy
Authors: Schoonheim Liesbeth
Published: December 2020

This essay is part of a dossier on Cristina Lafont's book Democracy without Shortcuts.
Феномен самоубийства в России XVIII в.
Authors: Каменский Александр
Published: December 2020

The history of suicide in Russia, especially prior to the nineteenth century, remains understudied. While in most European countries the process of decriminalization and secularization of suicide was underway, in Russia, with the introduction of the Military Article of 1715, it was formally criminalized. On the basis of the study of more than 350 newly examined archival cases, this article examines how the transfer of suicide investigations to secular authorities also entailed secularization, while the peculiarities of the Russian judicial and investigative system, as well as lacunae in the legislation, actually led to the gradual decriminalization of suicide. At the same time, although among Russians, as well as among other peoples, a number of superstitions were associated with suicide, there is no evidence in the archival documents studied in this article of a particularly emotional perception of suicide. The phenomenon of suicide in eighteenth-century Russia, when compared to early modern Europe, did not have any significant, fundamental differences. However, the features of the Russian judicial-investigative system made this phenomenon less public, less visible and less significant for public consciousness.
Замечания о рецепции итальянской оперы seria в период от царствования Анны Иоанновны до царствования Екатерины II
Authors: Джуст Анна
Published: December 2020

This article seeks to contribute to the ongoing revision of the historiography on eighteenth-century Russian music in general, and Russian opera in particular. After an extensive survey of the state of the field, the author adopts a multi-disciplinary approach (combining musical and philological studies) to analyse recently published primary sources about the reception of Italian opera seria in early imperial Russia. The article demonstrates that far from merely providing amusement for the Court of three consecutive female monarchs, Italian composers and their works engaged in complex ways with a much more variegated Russian "public." The author suggests that the creation of this music-listening and -performing domestic public was indebted to Italian operatic traditions and, at the same time, intimately connected to local traditions of musical performance.
Вивлiоѳика 2.1
Authors: Collis Robert , Zitser Ernest
Published: December 2020

Editorial
Research Output and International Cooperation Among Countries During the COVID-19 Pandemic: Scientometric Analysis (Preprint)
Authors: Grammes Nadja , Millenaar Dominic , Fehlmann Tobias , Kern Fabian , Böhm Michael , Mahfoud Felix , Keller Andreas
Published: December 2020

BACKGROUND

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has instigated immediate and massive worldwide research efforts. Rapid publication of research data may be desirable but also carries the risk of quality loss.

OBJECTIVE

This analysis aimed to correlate the severity of the COVID-19 outbreak with its related scientific output per country.

METHODS

All articles related to the COVID-19 pandemic were retrieved from Web of Science and analyzed using the web application SciPE (science performance evaluation), allowing for large data scientometric analyses of the global geographical distribution of scientific output.

RESULTS

A total of 7185 publications, including 2592 articles, 2091 editorial materials, 2528 early access papers, 1479 letters, 633 reviews, and other contributions were extracted. The top 3 countries involved in COVID-19 research were the United States, China, and Italy. The confirmed COVID-19 cases or deaths per region correlated with scientific research output. The United States was most active in terms of collaborative efforts, sharing a significant amount of manuscript authorships with the United Kingdom, China, and Italy. The United States was China’s most frequent collaborative partner, followed by the United Kingdom.

CONCLUSIONS

The COVID-19 research landscape is rapidly developing and is driven by countries with a generally strong prepandemic research output but is also significantly affected by countries with a high prevalence of COVID-19 cases. Our findings indicate that the United States is leading international collaborative efforts.

CLINICALTRIAL
The Effect of the Degree of Misfit Between Human Resources Management Practices and the Types of Organizational Culture on Organizational Performance
Authors: Kismono Gugup , Pradana Ramadista Raden Muhammad
Published: December 2020

“Fit model” argues that the level of misfit between human resources management (HRM) practices and the type of organizational culture negatively influences organizational performance. However, the lack of emprirical research to support that contention can be problematic. Utilizing the concept of fit, this study aims to examine empirically the effect of the degree of misfit between HRM practices and the types of organizational cultures on organizational performance. Data were collected from a sample comprising of 128 respondents representing 64 companies in Indonesia, from nine industrial sectors. The hypothetical model was developed based on four types of HRM practices (human relations, internal process, rational goals, and open systems) and four types of organizational cultures (clan, hierarchy, market, and adhocracy). Euclidean distance scores were calculated to describe the misfit between the HRM practices and the types of organizational culture variables. Subsequently, the effect of the misfit scores on organizational performance was determined. The results show that the degree of misfit between HRM practices and the type of organizational culture has a significant and negative effect on organizational performance. This empirical research supports the concept of fit, in which the type of organizational culture that is supported by suitable HRM practices will result in a more positive organizational performance. Then, it is deemed necessary for companies to adapt their HRM practices to their culture, in order to improve their performance.
Pengembangan Aplikasi People Management dalam Software Development dengan Pendekatan Project Management Antipatterns
Authors: Arshanty Reza Aprillia , Umi Sa'adah  , Desy Intan Permata Sari  , Maulidan Bagus Afridian Rasyid
Published: December 2020

Faktor manusia dalam proses pengembangan perangkat lunak menjadi salah satu penentu keberhasilan suatu proyek, terlepas dari teknologi dan tools yang digunakan. Dalam praktiknya, banyak project manager tidak memiliki dataset mengenai hard skill dan soft skill anggotanya. Hal ini mengantarkan tim proyek pengembangan perangkat lunak terjebak dalam situasi antipatterns irrational management. Berdasarkan beberapa faktor utama penyebab kegagalan proyek pengembangan perangkat lunak, diperlukan adanya suatu mitigation plan yang dapat membantu project manager dalam melakukan manajemen sumber daya manusia dalam sebuah tim. Mitigation plan yang dapat dilakukan adalah dengan mengembangkan aplikasi people management yang didasarkan pada prinsip-prinsip Project Management Antipatterns. Makalah ini mengajukan suatu pemodelan baru dalam bentuk aplikasi untuk melakukan people management di dalam pengembangan perangkat lunak dengan pendekatan Project Management Antipatterns. Penelitian ini mengajukan suatu pemodelan baru dalam bentuk aplikasi untuk melakukan people management di dalam pengembangan perangkat lunak dengan pendekatan Project Management Antipatterns. Hasil yang diberikan berupa pemetaan tim developer kepada task yang relevan berdasarkan hard skill dan soft skill yang dimiliki. Selain itu, aplikasi ini juga memberikan hasil berupa rekomendasi treatment yang bisa dilakukan terhadap tim untuk meningkatkan produktivitas serta mengurangi potensi risiko yang ditimbulkan dari hasil diagnosis praktik yang buruk. Pendekatan yang digunakan terbukti mampu meningkatkan produktivitas tim secara keseluruhan. Refactored solution yang direkomendasikan juga terbukti efektif menurunkan nilai antipatterns dari satu sprint ke sprint berikutnya.
Identifikasi Motif Jepara pada Ukiran dengan Memanfaatkan Convolutional Neural Network
Authors: Sandhopi  , Lukman Zaman P.C.S.W  , Yosi Kristian
Published: December 2020

Semakin berkembang motif ukiran, semakin beragam bentuk dan variasinya. Hal ini menyulitkan dalam menentukan suatu ukiran bermotif Jepara. Pada makalah ini, metode transfer learning dengan FC yang dikembangkan dimanfaatkan untuk mengidentifikasi motif khas Jepara pada suatu ukiran. Dataset dibedakan menjadi tiga color space, yaitu LUV, RGB, dan YcrCb. Selain itu, sliding window, non-max suppression, dan heat maps dimanfaatkan untuk proses penelusuran area objek ukiran dan pengidentifikasian motif Jepara. Hasil pengujian dari semua bobot menunjukkan bahwa Xception pada klasifikasi motif Jepara memiliki nilai akurasi tertinggi, yaitu 0,95, 0,95, dan 0,94 untuk masing-masing dataset color space LUV, RGB, dan YCrCb. Namun, ketika semua bobot model tersebut diterapkan pada sistem identifikasi motif Jepara, ResNet50 mampu mengungguli semua jaringan dengan nilai persentase identifikasi motif sebesar 84%, 79%, dan 80%, untuk masing-masing color space LUV, RGB, dan YCrCb. Hasil ini membuktikan bahwa sistem mampu membantu dalam proses menentukan suatu ukiran, termasuk ke dalam ukiran Jepara atau bukan, dengan mengidentifikasi motif-motif khas Jepara yang terdapat dalam ukiran.
Rekayasa Proses Bisnis Sistem Surveilans Penyakit Tidak Menular berbasis IoT
Authors: Asfy Fakhry Anto Irfan
Published: December 2020

Surveilans merupakan kegiatan analitis, sistematis, dan periodik terhadap penyakit atau gejala kesehatan agar dapat dilakukan tindakan penanggulangan secara efektif dan efisien melalui proses pengumpulan data, pengolahan, dan penyebaran informasi epidemiologi kesehatan kepada penyelenggara layanan kesehatan. Perkembangan teknologi dapat diaplikasikan untuk kegiatan surveilans kesehatan, salah satunya adalah teknologi Internet of Things (IoT). Makalah ini bertujuan mengidentifikasi dan menganalisis proses bisnis yang sedang berjalan, kemudian melakukan rekayasa proses bisnis, khususnya pada proses bisnis surveilans penyakit tidak menular dengan pendekatan teknologi berbasis IoT. Metodologi yang digunakan yaitu business process improvement. Makalah ini menghasilkan desain hasil proses bisnis dari tahapan-tahapan yang dilakukan, antara lain identifikasi, analisis proses bisnis, rekayasa atau perbaikan proses bisnis, dan evaluasi proses bisnis sebelum dan sesudah perbaikan. Hasil simulasi proses bisnis menunjukkan bahwa rekayasa yang dilakukan dapat mengurangi waktu proses, yaitu lebih efisien rata-rata 62,9 menit, atau sebesar 78,77%, sehingga dapapt dikatakan bahwa rekayasa proses bisnis surveilans pencegahan penyakit tidak menular berbasis IoT lebih efisien dalam melakukan aktivitasnya.
Reflexiones de profesionales de la enfermería en torno a la actual pandemia y las bibliotecas
Authors: Jiménez Mendoza Araceli , Hernández Falcón Julio , Pérez Cabrera Iñiga
Published: December 2020

Objetivo: Reflexionar acerca del entorno bibliotecario en el escenario COVID–19.Desarrollo: La pandemia causada por el coronavirus SARS-COV2 ha provocado el cierre presencial de las bibliotecas, pero sus profesionales ofrecen sus servicios gracias al Internet a través de distintas plataformas digitales. Esto ha acelerado la evolución socio-histórica del entorno bibliotecario transformando en poco tiempo el significado, la organización, los roles de sus participantes y las tecnologías incorporadas, elementos sustanciales para responder ante la pandemia por COVID–19. Los espacios virtuales acogieron al público para aportar los recursos generadores de conocimiento, pero también brindar esparcimiento y confort en el distanciamiento físico. En el caso del personal de enfermería, presente en el cuidado más inmediato del paciente y la familia, la información fidedigna y de calidad significa actuar con base en los avances del manejo de la nueva enfermedad con certeza y seguridad. Ante este escenario de la COVID–19 han surgido como eje central las enfermeras y los enfermeros, que junto con el equipo de salud brindan a la población los cuidados actualizados con la información en línea que las bibliotecas y los bibliotecarios han puesto a su alcance en todas las latitudes, para dar la atención a los enfermos y para su protección. Conclusión: En la nueva normalidad los entornos de las bibliotecas no serán iguales, se transformarán en esa resiliencia que les ha caracterizado, garantizando seguridad sanitaria, preservándose con nuevas propuestas para satisfacer los requerimientos de las diversas generaciones de usuarios, entre ellos los profesionales de Enfermería quienes fieles a su mística de cuidado cimentado en el conocimiento basado en evidencia, seguirán impulsando acciones para el empoderamiento disciplinar en un escenario de continua transformación.
Estrategias empresariales ante la COVID-19: el caso de la industria curtidora de León, Guanajuato
Authors: Rodríguez González Juan Antonio , Tagle Zamora Daniel , Granados Márquez Gustavo
Published: December 2020

Objetivo: analizar qué estrategias han implementado los empresarios del sector curtidor en León, Guanajuato ante la COVID-19, para conocer cómo han sobrevivido a la crisis sanitaria y económica en el 2020.Diseño metodológico: se trata de un estudio descriptivo, en el cual se capta el deterioro económico causado por el problema de salud mundial mediante la aplicación de una encuesta a los actores económicos de esta industria. Así como entrevistas al director y al coordinador de Recursos Humanos de la Cámara de la Industria de la Curtiduría (Cicur).Resultados: estos muestran las múltiples afectaciones económicas que se traducen en disminución de la producción y pérdida de empleos con una elevada incertidumbre para la reapertura, así como las estrategias que los empresarios del sector han implementado.Limitaciones: si bien la interacción cara a cara con los actores del proceso productivo es fundamental, debido a la contingencia sanitaria tuvimos que acudir de manera conjunta con la Cicur a las plataformas virtuales para la aplicación de la encuesta. Dicho instrumento fue diseñado en equipo por la Cicur y los investigadores, siendo estos últimos los encargados de analizar los resultados y emitir un informe de estos.Hallazgos: ante la crisis derivada de la COVID-19, los empresarios de la industria de la curtiduría en León, Guanajuato han implementado estrategias de sobrevivencia para mantener la producción. Asimismo, tanto los gobiernos locales como los actores productivos locales, han implementado estrategias encaminadas al fortalecimiento de las dinámicas económicas locales.
El ciclo de Randle, el precario vínculo entre azúcares y grasas
Authors: Matus-Ortega Genaro , Romero-Aguilar Lucero , González James , Guerra Sánchez Guadalupe , Matus-Ortega Maura , Del Castillo-Falconi Víctor , Pardo Juan Pablo
Published: December 2020

La obesidad es un problema de salud global, asociada con enfermedades cardiovasculares. El análisis de la relación existente entre el elevado consumo de glucosa y la concomitante formación de depósitos de grasa, descrita por el ciclo de Randle, permitirá desarrollar una comprensión de los procesos metabólicos involucrados en el balance entre la formación y la degradación de los lípidos. Esta revisión tiene como objetivo, proporcionar una actualización del ciclo y de sus diferentes niveles de regulación, así como la participación de mTORC1 y la cinasa dependiente de AMP (AMPK) durante el estado postprandial y de ayuno.
Low-dose Psoralen–UV-A maintenance therapy prolongs disease-free remission rates in mycosis fungoides patients
Authors: Brady Joshua M.
Published: December 2020

A clinical decision report using Vieyra-Garcia P, Fink-Puches R, Porkert S, et al. Evaluation of Low-Dose, Low-Frequency Oral Psoralen–UV-A Treatment With or Without Maintenance on Early-Stage Mycosis Fungoides. JAMA Dermatology. 2019;155(5):538. https://doi.org/10.1001/jamadermatol.2018.5905 for a patient weighing whether to continue treatment in light of socioeconomic circumstances.
Ceramids as biomarkers of chronic periodontitis associated with type 2 diabetes
Authors: Unanyan K. G. , Balmasova I. P. , Tsarev V. N. , Mkrtumyan A. M. , Elbekyan K. S. , Karakov K. G. , Arutyunov S. D.
Published: December 2020

Relevance . The association of chronic periodontitis with type 2 diabetes mellitus is one of the most frequent manifestations of systemic effects that are etiologically associated with periodontopathogenic bacteria in the biofilm of the gingival sulcus. In this regard, the study of the metabolic mechanisms leading to such systemic effects and serving their markers is an urgent problem. Aim . Study of the features of sphingolipid/ceramide metabolism, both produced by etiologically significant microflora, and present in periodontal tissues of patients on the example of the association of chronic periodontitis with type 2 diabetes. Materials and methods . The observation groups included 58 patients with chronic periodontitis in association with type 2 diabetes, 39 patients with chronic periodontitis without concomitant systemic pathology, and 27 conditionally healthy people. All the examined patients underwent molecular genetic studies of the taxonomic and metabolic profiles of the dental sulcus/ periodontal pockets microbiota using 16S sequencing and evaluation of phosphorylated ceramides in saliva by the activity of the ceramid kinase enzyme. Results . It was found that in the Association of chronic periodontitis with type 2 diabetes mellitus, there are features of the taxonomic composition of the dental sulcus/periodontal pockets microbiota, which are combined with a decrease in sphingolipid metabolism. In addition, in these patients, depending on the duration of diabetes mellitus, there was an increasing drop in the saliva of ceramide kinase, which determines the phosphorylation of sphingolipids/ceramides. Conclusion . In the Association of chronic periodontitis with type 2 diabetes mellitus, the systemic effects of the dental sulcus/ periodontal pockets microbiota are manifested by a decrease in sphingolipid metabolism, including a decrease in ceramide kinase in periodontal tissues, which can serve as a marker of the combined pathological process.
Immunopathogenetically reasonable program effectiveness of systemic and local interferonotherapy in immunocompromised young children
Authors: Nesterova I. V. , Kovaleva S. V. , Khalturina E. O. , Chudilova G. A.
Published: December 2020

Relevance. In recent years, there has been a steady increase in the incidence of children morbidity, in the structure of which infectious pathology occupies a leading position. The development of minimal persistent inflammation of the upper respiratory tract mucosa is the basis for the persistence of microflora, the entrance gate for allergens and irritants, and creates conditions for the timing of the inflammation. The aim of the study: based on the study of the features of the immune system and interferon system in immunocompromised children of early age suffering from co-infections: return ARVI associated with atypical chronic herpes virus infections, to develop a new program of local and systemic interferon therapy and evaluate its effectiveness. Materials and methods: We observed 30 children aged 1-4 years, 16 boys and 14 girls suffering from recurrent ARVI associated with various atypical chronic active herpes virus infections (ACHA-HVI) (HSV I/II, EBV, CMV, HHV VI). The comparison group was 20 conditionally healthy children, comparable by sex and age. We used clinical and immunological methods: ELISA, PCR, cytofluorimetry. Results: A clinical and anamnestic investigation showed that young children had clinical features of immunocomprometization: a high rate of recurrent ARVI of 10-15 or more episodes per year, and the duration of these episodes ranged from 7 to 12 days, while in 100 % of cases there were recurrent monoand/or mixed ACHA-HVI. A study of the state of the immune system and the interferon system showed that children of the study group were deficient in T cytotoxic lymphocytes, natural killer cells, serum IFN, serum IgA, and various disorders of neutrophil granulocytes (NG). A new immunopathogenetically based program of local and systemic therapy with recombinant IFN2b in combination with antioxidants has been developed. This program demonstrated a high clinical-immunological effectiveness, providing in a significant reduction of ARVI episode rates, a reduction in the duration of IRVI, as well as the number of complicated ARVI, a decrease in the replicative activity of herpes viruses in a field of restoration of the interferon system, a significant improvement of antiviral and antibacterial immune response. Conclusions: A new immunopathogenetically based program of systemic and local IFNtherapy for immunocompromised young children has been created. The high clinical-immunological effectiveness and immunoprophylactic orientation of the developed local and systemic program of interferonotherapy have been demonstrated.
Aphorism as an Object of Linguistics: the Main Properties
Authors: Ivanov Eugene E.
Published: December 2020

The article presents an attempt to establish and describe the main properties of aphorism as an object of linguistics. In modern linguistics, a number of researches are devoted to the study of aphorism as a phrase text and a fixed phrase. However, the concept of aphorism in linguistics does not have its own definition. In this regard, the analysis of the linguistically relevant properties of the aphorism that characterize its linguistic nature is of current importance. The purpose of the study is to determine and describe the minimum number of the most linguistically significant properties of an aphorism, to establish their obligatory / optional character, their specificity / generality (for aphorism and more than a word units close to it). Research methods - descriptive method, structural, semantic, functional, discursive, stylistic analysis, taxonomy. The material for the research was the statements in Russian, English, Belarusian, Polish, contained in written texts of different genres, as well as in compilations from various sources, in reference editions, in the title of which the term aphorism (or its derivative - aphoristic ) was used. The total number of analyzed units is over 50,000 from over 120 sources. As a result of the study, it was found that linguistically relevant properties of aphorism (differentiating it as an object of linguistics) are more than a word nature, one phrase structure, generalized meaning, nominative nature, discursive autonomy, textuality, reproducibility, stability, idiomatic nature, expressiveness of the verbal form. A number of properties coincide in aphorisms and phraseological units (more than word nature, reproducibility, stability, idiomatic nature), but none is obligatory for aphorism. Obligatory properties of aphorism are one phrase structure, generalized meaning, nominative nature, discursive autonomy. The main (differential) property of aphorism as an object of linguistics is the generalized meaning, which in relation to the expressed reality has a specific character - universal character. The introduction of linguistically relevant features of aphorism into science allows it to be defined in terms of linguistics as a one-phrase unit, nominative, discursively autonomous, predominantly more than a word units, reproducible, fixed unit that differs from all other more than a word units in one specific property - the generalized meaning (a universal generalization of reality). This property characterizes aphorisms as a variety of linguistic units (phrase texts or fixed phrases), determines their discursive autonomy and nominative nature, and manifests the categorical quality of their content plan - aphoristic nature.
Ta-Marbuta as Grammatical and Semantic Indicator: Harf or Affix?
Authors: Zarytovskaya Victoria N.
Published: December 2020

The article discusses the functional significance of such a graphic embodiment of the letter ta as ta-marbuta (ta-linked), which is not available in the Arabic alphabet. Traditionally included in Arabic studies in the phonetics-graphic section as a phenomenon specific to writing and reading rules, as well as a narrow grammar paragraph related to the female category indicator, ta-marbuta, as follows from the semantic comparison of the Arabic words selected by us, which in their own way morphological composition differ only in the presence of this affix, performs a more complex role in the language. The question is raised about the correctness of the name of ta-marbuta by letter (harf) or affix, the characteristics of which are inherent in it. The wide range of uses of ta-marbuta as a feminine affix, uniqueness affinity, substantiation, etc., as well as open and systematized semantic distinguishing shades of words with the same basis with ta-marbuta and without it, allow us to say that this affix has to be established as multifunctional and operates at various levels of the language - from morphology to semantics. Based on an analysis of the vast material, conclusions are drawn about the high productivity of ta-marbuta as an inflectional and word-formation formant, which allows transmitting a number of qualifying values, and not just a female affix. The lists of words that participate in word formation along with this affix are clarified - masdars of certain types of the verb, collective names, relative adjectives, less often high-quality adjectives, etc. All this ultimately speaks of the Arabic as a modern and developed language that can convey the most subtle semantic nuances, as well as having great potential for the formation of new lexical units.
La raza negra en el Chocó: antropología física
Authors: Pujol Nicole
Published: December 2020

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Barrio piloto: variables económicas y culturales de una erradicación de tugurios en Cali, Colombia
Authors: Ashton Guido T.
Published: December 2020

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Contribución al conocimiento del Cacique-Curaca entre los Siona
Authors: Mallol de Recasens María Rosa , De Recasens T. José
Published: December 2020

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Dibujo infantil y personalidad cultural en la Isla de San Andrés
Authors: Mallol de Recasens María Rosa , De Recasens José
Published: December 2020

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Estatuas prehistóricas de piedra del valle de Chimayoy
Authors: Ortiz Sergio Elías
Published: December 2020

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Notas informativas
Authors: Márquez Yáñez Francisco
Published: December 2020

Notas informativas de:

El V congreso indigenista interamericano

El VII congreso internacional de ciencias antropológicas y etnológicas en Moscú