bluuebunny/crossref_metadata_2025 huggingface dataset:
Recurrent Hypertriglyceridemia-Induced Pancreatitis due to Multifactorial Chylomicronemia Syndrome in a Patient With Ketosis-Prone Diabetes Mellitus
Authors: Yotsapon Thewjitcharoen , Surat Komindr , Veekij Veerasomboonsin , Kewalin Wattanawiroon , Soontaree Nakasatien , Sirinate Krittiyawong , Thep Himathongkam
Published: August 2022

The triad of diabetic ketoacidosis (DKA), severe hypertriglyceridemia, and acute pancreatitis have been occasionally described in severely obese patients with type 2 diabetes mellitus (T2DM). Herein, we present a long-term clinical course of a Thai man with ketosis-prone diabetes mellitus (KPDM) complicated with recurrent pancreatitis due to multifactorial chylomicronemia syndrome. Genetic testing showed no mutation in lipoprotein lipase (LPL) and its co-factors. The patient was referred to multidisciplinary team for lifelong weight loss consultation, limiting intake of fat and simple carbohydrates, and adherence to lipid-lowering medications. Subsequent follow-up 1 year later showed no recurrent pancreatitis. In patients with multifactorial chylomicronemia syndrome, long-term management with dietary modifications together with pharmacotherapy remains the cornerstone of successful treatment.
An Unforeseen Alliance: The Experience of Mental Health Professionals when Testifying in Sexual Assault Criminal Proceedings
Authors: Cohen Inbar
Published: August 2022

Introduction: Court testimonies of mental health expert witnesses (MHEWs) received scholarly attention regarding paradigmatic differences, and ethical issues, neglecting the testimony experience. The study examines MHEWs’ testimony experience in sexual assault proceedings in Israel. Methods:16 interviews. MHEW were recruited using chain referral sampling. Interviews were analyzed based on the constructive dialectical model. Results: Three main themes were conceptualized: MHEWs’ initial image of the court, their perception of mental health and legal languages, and their perception of court conduct as a theatrical play. The themes address the experience of tension between law and mental health along with an unprecedented experience of congruence that emerges when: 1. MHEWs based their testimonies on evidence-based tests and therapeutic interventions which value objectivity, as opposed to focusing primarily on the subjective experience, accommodating the evidence-based legal debate; 2. When MHEWs and legal practitioners formed an interpersonal connection, in accordance with key relational therapeutic elements.
Novel climate tort? The New Zealand Court of Appeal decision in Smith v Fonterra Co-operative Group Limited and others
Authors: Foster Caroline E.
Published: August 2022

In Smith v Fonterra the New Zealand High Court and Court of Appeal struck out all causes of action in proceedings seeking orders that seven New Zealand companies cease direct and indirect greenhouse gas emissions by 2030 grounded in the three distinct claims of negligence, public nuisance and a proposed novel tort referred to as “breach of duty”. The Court of Appeal's judgment is under appeal before the New Zealand Supreme Court. This commentary seeks to open up discussion around the reasons given for the various aspects of the judgment. In particular the commentary puts the view that there is scope for the creation of a novel common law climate tort. This tort must be forward-looking and preventive in orientation and may differ fundamentally from existing torts.
The gift of waste: The diversity of gift practices among dumpster divers
Authors: Pyyhtinen Olli , Lehtonen Turo-Kimmo
Published: August 2022

While the circular economy invites us to realize the potential of the so-called ‘waste-based commodity frontiers’, reintegration into capitalist value chains is not the only way for discards to be resurrected. In this article, we examine the ways in which the collective of dumpster divers is organized in relation to giving, receiving and reciprocating of various waste-gifts. Our intention is not only to expand existing theorizations of the gift to new domains but also to critically interrogate them, identify their limitations and explore what dumpster diving can teach us about the gift. In particular, the analysis foregrounds the heterogeneity of gift practices. Arguing against universal notions of the gift, the article proposes that waste assumes four main forms of gifts and relations among dumpster divers: givenness (parasitic relation); solidarity-based giving (relation of reciprocity); free giving (asymmetrical relation); and non-giving, as a withdrawal from returning the discards to nature conceived as an Other (the relation of non-relation).
Grappling with the miseducation of Montessori: A feminist posthuman rereading of ‘child’ in early childhood contexts
Authors: Osgood Jayne , Mohandas Sid
Published: August 2022

This article demonstrates how feminist posthumanism can reconfigure conceptualisations of, and practices with, ‘child’ in Montessori early childhood contexts. It complicates Montessori’s contemporary reputation as a ‘middle-class phenomenon’ by returning to the earliest Montessori schools as a justice-oriented project for working-class children and families. Grappling with the contradictions and inconsistencies of Montessori thought, this article acknowledges the legacy of Montessori’s feminism while also situating her project within the wider colonial capitalist context in which it emerged. A critical engagement with Montessori education unsettles modernist conceptualisations of ‘child’ and its civilising agenda on minds and bodies. Specifically, Montessori child observation (as a civilising mission) is disrupted and reread from a feminist posthumanist orientation to generate more relational, queer and expansive accounts of how ‘child’ is produced through observation. Working with three ‘encounters’ from fieldwork at a Montessori nursery, the authors attend to the material-discursive affective manifestation of social class, gender, sexuality and ‘race’, and what that means for child figurations in Montessori contexts. They conclude by embracing Snaza’s ‘bewildering education’ to reach towards different imaginaries of ‘child’ that are not reliant on dialectics of ‘human’ and ‘non-human’, and that allow ‘child’ to be taken seriously, without risking erasure of fleshy, leaky, porous, codified bodies in Montessori spaces.
Rethinking collaborative planning in China: Does the communicative or agonistic planning theory matter?
Authors: Lin Yanliu
Published: August 2022

There has been considerable debate about Habermasian-inspired communicative planning theory and Mouffe’s-inspired agonistic planning theory. This study investigates the possibility of the communicative and agonistic approaches for collaborative planning in the Chinese context. It examines three common theoretical dimensions, regarding the political concept, the public sphere and the power relation. The recent political development in China is related to authoritarian deliberation, in which governments allow some space for deliberation and participation but with limited empowerment. The multiple tensions between governments and society lead to the fragmentation of public spheres and various forms of power relations in collaborative practices. This study concludes that a dichotomous perspective is not helpful to understand China’s collaborative planning, which reflects features of both communicative and agonistic approaches.
Bridge modal property identification based on asynchronous mobile sensing data
Authors: Eshkevari Soheil Sadeghi , Cronin Liam , Matarazzo Thomas J , Pakzad Shamim N
Published: August 2022

There is a growing attention in real-time bridge condition assessment using data from drive-by vehicles as a potentially scalable approach. Most system identification methods are based on synchronized vibration data collection for this purpose. This study presents an approach for bridge modal identification that estimates high-resolution absolute value of the operational mode shapes using asynchronous mobile data. With each trip of a vehicular sensor, the spatio-temporal response of the bridge is sampled, along with various sources of noise, e.g. vehicle dynamics, environmental effects, road profile, etc. The crowdsourced modal identification using continuous wavelet (CMICW) method is proposed that gradually magnifies the bridge dynamical signatures and mitigates noise over the spatio-temporal map. The performance of the CMICW method is validated in an experimental setting. The method successfully identifies natural frequencies and absolute value of the operational mode shapes of a bridge with high resolution and accuracy. Notably, by including data collected from various bridge lanes, the method can reconstruct 3D representation of the mode shapes. The influence of the speed of the mobile sensors on the accuracy of the estimated modal properties is investigated as well. Using a hybrid simulation framework, the effect of vehicle dynamic is included in the mobile sensing data. The study shows that the CMICW method is successful in discounting the effect of vehicle dynamics, thereby strengthening the bridge modal information. Finally, a blind source separation technique is implemented to separate the effects of road irregularities, which further improves the accuracy of modal property estimates. This study contributes to the growing body of knowledge on mobile crowdsensing for physical properties of transportation infrastructure.
Seeing business like a state: Firms and industries after the digital revolution
Authors: Davis Gerald F , DeWitt Theodore
Published: August 2022

What we know about firms and industries in the United States has been fundamentally shaped by governmental responses to the Great Depression. Mandates for regular disclosures by public corporations and a system of industry categories created for surveys of establishments gave us a synoptic view of the economy that served us well for generations. They also molded the development of the fields of strategic management and organization theory. But the tools and frameworks that made sense in the 1930s are a poor fit with the enterprises we encounter today. Basic terms like firm, industry, size, performance, employee, and nationality are contested. The field of strategic organization may be the academic discipline best suited to helping us transition to a new way of making sense of the organization of the economy.
Doing safe while doing good: Slack, risk management capabilities, and the reliability of value creation through CSR
Authors: Lu Hao , Liu Xiaoyu , Osiyevskyy Oleksiy
Published: August 2022

When can corporate social responsibility become a reliable strategic asset? There is a scarcity of both theoretical arguments and empirical evidence investigating the trade-off between the risk and return of corporate social responsibility. We intend to fill this gap by (1) investigating corporate social responsibility’s simultaneous impact on firm value and the reliability of this impact and (2) exploring the conditions under which corporate social responsibility’s impact on firm value becomes more or less reliable. The presented findings suggest that corporate social responsibility by itself is an unreliable value enhancer, in that it not only increases firm value but also increases the variance of expected value distribution. Yet, the impact of corporate social responsibility on firm value becomes more reliable when a firm has immediately redeployable slack or when a firm has stronger risk management capabilities. This research provides practical implications to managers and investors regarding the riskiness of corporate social responsibility investments and strategies for mitigating such risks.
Looking forward, looking back: Strategic organization and the business model concept
Authors: Snihur Yuliya , Eisenhardt Kathleen M
Published: August 2022

In the past decade, the business model has emerged as a fundamental strategic and organizational concept. In this essay, we first “look back” to synthesize recent research on designing high-performing business models into two influential research streams. Managerial cognition grapples with the role of holistic mental models and strategic thinking for designing effective configurations of business model attributes. Learning processes address the uncertainties that emerge from the major disruptions that create opportunities for new business models. We then “look forward” to the exciting work on business models that remains for both extending current research and exploring broad societal impacts. Overall, we argue that the business model is rapidly replacing strategy as the most significant source of competitive advantage.
A Crisis of Social Democracy in Europe? An Answer from the Citizens’ Perspective
Authors: Palacios Irene
Published: August 2022

This article analyses the public support for the social model of democracy by focusing on the gap between what citizens expect democracy to deliver in the social realm and how they do evaluate its achievement in the practice. Using data from the European Social Survey Round 6 (2012), the results reveal that individuals with a lower socio-economic background, those positioned on the left and those who are more distrustful of political institutions tend to be more supportive of social democracy, while they evaluate its performance more negatively. The data also demonstrate that individuals’ social expectations and evaluations are moderated by their country’s institutional configuration of the welfare state, and more particularly, its degree of universalism. Overall, the results support the intuition that the alleged crisis of social democracy does not exist generally across Europe, but only in those countries where the welfare state has been unable to close the gap between expectations and evaluations.
Specially and Regularly Admitted Division I Student-Athletes: Differences in and Relationships Between Academic and Athletic Identity, Perceived Support, and Academic Commitments
Authors: Yukhymenko-Lescroart Mariya A. , Moradian Watson Jennifer , O’Quin Megan
Published: August 2022

The purpose of this study was to examine academic commitments in Division I specially and regularly admitted student-athletes. Division I student-athletes completed questionnaires assessing academic and athletic identity, perceived academic support, degree commitment, institutional commitment, and intent to withdraw. Structural equation modeling showed that institutional commitment was predicted positively by degree commitment and perceived academic support. It was also predicted by academic identity indirectly through degree commitment. Intent to withdraw was predicted negatively by degree commitment, athletic identity, and perceived academic support. Both institutional commitment and intent to withdraw were also predicted by academic identity indirectly through degree commitment. Compared to regularly admitted student-athletes, specially admitted student-athletes reported lower academic and athletic identities, lower perception of academic support from staff, and lower commitment to their degree, which contributed to their lower institutional commitment and higher intent to withdraw. Findings highlight the importance of academic integration of student-athletes.
Intensive Cognitive-Behavioral Therapy for Anxiety Disorders in Adolescents: A Case Study
Authors: Hudson Kelsey , Fenley Alicia R. , Pincus Donna B. , Leyfer Ovsanna
Published: August 2022

Anxiety disorders are one of the most common psychiatric conditions in youth and can contribute to impairment in social, academic, and family functioning. Cognitive-behavioral therapy (CBT) has been shown to be efficacious in treating youth anxiety disorders; however, for a multitude of reasons, fewer than 20% of adolescents with anxiety disorders receive services for anxiety-related problems. Intensive treatments, which rely on the same traditional components of CBT but are delivered over a shorter period of time or in a fewer number of sessions, may be particularly helpful for anxiety disorders and can offer a number of advantages over standard CBT. Despite emerging evidence supporting the advantages of the intensive approach, there are few established intensive treatment programs for youth with anxiety disorders. Further, no treatment to date has comprehensively targeted the entire spectrum of comorbid adolescent anxiety disorders in a combined intensive and transdiagnostic format, even though non-intensive (i.e., weekly delivered) CBT has been tested using a transdiagnostic approach. We developed an intensive, six-session intervention based on Angelosante and colleagues’ 2009 The Adolescent Panic Control Treatment with In-Vivo Exposures (Angelosante et al., 2009) and other empirically-supported treatments for youth to target all anxiety disorders in adolescents. We present a case study on an adolescent with multiple comorbid anxiety and related disorders who received intensive CBT treatment as a way to illustrate the clinical benefit and utility of an intensive, transdiagnostic approach. Findings support the acceptability and feasibility of transdiagnostic treatment of youth anxiety.
The Bayesian Time Machine: Accounting for temporal drift in multi-arm platform trials
Authors: Saville Benjamin R , Berry Donald A , Berry Nicholas S , Viele Kert , Berry Scott M
Published: August 2022

Background

Multi-arm platform trials investigate multiple agents simultaneously, typically with staggered entry and exit of experimental treatment arms versus a shared control arm. In such settings, there is considerable debate whether to limit analyses for a treatment arm to concurrent randomized control subjects or to allow comparisons to both concurrent and non-concurrent (pooled) control subjects. The potential bias from temporal drift over time is at the core of this debate.

Methods

We propose time-adjusted analyses, including a “Bayesian Time Machine,” to model potential temporal drift in the entire study population, such that primary analyses can incorporate all randomized control subjects from the platform trial. We conduct a simulation study to assess performance relative to utilizing concurrent or pooled controls.

Results

In multi-arm platform trials with staggered entry, analyses adjusting for temporal drift (either Bayesian or frequentist) have superior estimation of treatment effects and favorable testing properties compared to analyses using either concurrent or pooled controls. The Bayesian Time Machine generally provides estimates with greater precision and smaller mean square error than alternative approaches, at the risk of small bias and small Type I error inflation.

Conclusions

The Bayesian Time Machine provides a compromise between bias and precision by smoothing estimates across time and leveraging all available data for the estimation of treatment effects. Prior distributions controlling the behavior of dynamic smoothing across time must be pre-specified and carefully calibrated to the unique context of each trial, appropriately accounting for the population, disease, and endpoints.
From blazing to burnt out: Spontaneous regression of a testicular germ cell tumour
Authors: Wijnberg Alexander , Hadden Rob , Freeman Simon
Published: August 2022

Introduction:

It is a rare, but recognised phenomenon that malignant testicular germ cell tumours can ‘burn-out’, where the primary lesion spontaneously regresses and presents with no viable remaining malignant cells leaving only a residual ‘tumour scar’, frequently in the context of distant metastatic disease

Case Report:

We present a case report of a patient who underwent serial ultrasound scans documenting regression of a testicular lesion from a malignant appearance to a burned-out lesion, where subsequent resection and histology demonstrated features of a completely regressed seminomatous germ cell tumour with no residual viable tumour cells.

Discussion:

To the best of our knowledge, there are no previously documented cases where a tumour has been longitudinally followed from sonographic features of concern for malignancy to ‘burned-out’ appearances. Spontaneous testicular tumour regression has instead been inferred based on the presence of a ‘burned-out’ testicular lesion in patients presenting with distant metastatic disease.

Conclusion:

This case provides further evidence supporting the concept of spontaneous testicular germ cell tumour regression. Ultrasound practitioners should be aware of this rare phenomenon in men presenting with metastatic germ cell tumour and, additionally, that this condition may present with acute scrotal pain.
Self-reported mental well-being of mothers with young children during the first wave of the COVID-19 pandemic in Germany: A mixed-methods study
Authors: Wandschneider Lisa , Batram-Zantvoort Stephanie , Alaze Anita , Niehues Vera , Spallek Jacob , Razum Oliver , Miani Céline
Published: August 2022

Objectives:

Mothers of young children have been identified as a particularly vulnerable group during the COVID-19 pandemic. We aimed to explore how occupational, psychosocial and partnership-related factors were associated with their self-reported mental well-being during the first COVID-19 wave.

Methods:

Five hundred fifty participants of the BaBi cohort study (est. 2013, Bielefeld, North-Rhine Westphalia, Germany) were invited to complete an online survey and to take part in email interviews (April–May 2020). With survey data, we assessed self-reported mental well-being through validated instruments (eight-item Patient Health Questionnaire; short version of the Symptom Checklist) and ran linear regression models for occupational, psychosocial and partnership-related factors. We performed content analysis on the interviews’ data to further understand the determinants of the women’s mental well-being.

Results:

One hundred twenty-four women participated in the survey; of which 17 also participated in the interviews. A perceived lack of support in childcare was associated with higher levels of depressive symptoms, while having a higher internal locus of control was associated with lower levels. Psychological distress was higher in those reporting lack of emotional or childcare support. Interviews confirmed the interplay of potential stressors and highlighted the difficulties to reconcile different expectations of motherhood.

Discussion:

Occupational, psychosocial and partner-related factors can act (to varying degree) both as resources and stressors to the self-reported mental well-being of mothers of young children. These impacts took different forms and created opportunities or challenges, depending on specific life circumstances, such as work or family situations, relationships and own psychosocial resources. Although not representative, our study contributes to building the COVID-19 evidence base, delineating the mental health toll of the pandemic on mothers of young children and the factors that contribute to it.
Awe as a Pathway to Mental and Physical Health
Authors: Monroy Maria , Keltner Dacher
Published: August 2022

How do experiences in nature or in spiritual contemplation or in being moved by music or with psychedelics promote mental and physical health? Our proposal in this article is awe. To make this argument, we first review recent advances in the scientific study of awe, an emotion often considered ineffable and beyond measurement. Awe engages five processes—shifts in neurophysiology, a diminished focus on the self, increased prosocial relationality, greater social integration, and a heightened sense of meaning—that benefit well-being. We then apply this model to illuminate how experiences of awe that arise in nature, spirituality, music, collective movement, and psychedelics strengthen the mind and body.
BBC Africa Eye and changing perceptions of Western media among Nigerian audiences
Authors: Nwakpu Ekwutosi Sanita
Published: August 2022

Although the dominant narrative among Africans is that Western media portray Africa in a one-sided and negative way, this belief is being challenged as a result of the intervention of the BBC’s Africa Eye documentaries. Although the series focuses on the dark side of Africa, it succeeds in revealing, in great detail, hidden stories about Africa, particularly Nigeria, of which many citizens were ignorant. As such, negative coverage may help to correct social anomalies and chart a way forward for correcting them. This development is a game-changer that has restored Nigerian audiences' confidence in Western media.
Algorithmic prediction of anaesthesia manpower quantity needs: A multicentre study
Authors: Akavipat Phuping , Suraseranivongse Suwannee , Yimrattanabowon Patcharee , Sriraj Wimonrat , Ratanachai Prapa , Summart Ueamporn
Published: August 2022

Background:

A shortage of anaesthetists affects health system globally. This is a study on task-force to develop a predictive model for the appropriate number of anaesthetic providers (Y).

Methods:

A cross-sectional study was performed with randomisation from every health service region across Thailand. The decision-making criteria for manpower needed were written and provided guidance. The number of personnel was calculated from the sum of total time spent by all anaesthetic providers divided by duration of the service. Linear regression analysis was applied.

Results:

In total 3774 patients were included from 18 hospitals. The factors that affect the anaesthetic providers’ allocation needs were included in the predictive model, calculated as Y = 3.53 + [0.56 (standard centre) + 0.36 (advanced centre) + 1.03 (specialty centre)] + 0.07 (American Society of Anesthesiologists physical status IV and V) + 0.61 (advanced anaesthetic medication) + [0.61 (monitored anaesthesia care) + 0.17 (general anaesthesia)] − [0.27 (pre-anaesthetic duration within 31–60 minutes) + (0.61 (over 60 minutes)] − [0.85 (anaesthetic duration within 31–60 minutes) + 1.04 (within 61–120 minutes) + 1.32 (over 120 minutes)] – [0.16 (post-anaesthetic duration within 31–60 minutes) + 0.45 (within 61–90 minutes) + 0.74 (over 90 minutes)].

Conclusion:

The anaesthesia manpower algorithm developed during this study can be used to calculate the number of anaesthetists per population to maintain health services.
Ureteroscopy for stone disease in the paediatric population: lessons learned and outcomes in a Nordic setting
Authors: Juliebø-Jones Patrick , Æsøy Mathias Sørstrand , Gjengstø Peder , Beisland Christian , Ulvik Øyvind
Published: August 2022

Introduction:

Paediatric stone disease is rare in the Nordic communities. Still, the condition can require surgical intervention in the form of ureteroscopy (URS). Here, we report outcomes achieved at a regional (tertiary) centre.

Patients and methods:

Retrospective analysis was performed of consecutive patients (<18 years of age) undergoing URS for stone disease between 2010 and 2021. Outcomes of interest included stone-free rate (SFR) determined using a definition of no residual fragments ⩾ 3 mm on imaging and complications classified according to Clavien–Dindo system.

Results:

In total, 23 patients underwent 47 URS procedures for a total of 31 stone episodes. Mean age was 9 (range 1–17) years and male-to-female ratio was 6:17. Overall, 35% had at least one medical comorbidity. Ultrasound determined preoperative stone status in 87%. Mean largest index and cumulative stone sizes were 9 (range 3–40) and 12 (range 3–40) mm, respectively. Overall, 32% had multiple stones. Lower pole was the commonest stone location (39%). No patients underwent elective pre-operative stenting. Ureteral access sheaths were not used in any cases. Access to upper urinary tract at first procedure was successful in 94%. Initial and final SFR was 61% and 90%, respectively. No intra-operative complications were recorded. Overall post-operative complication rate was 17.5%. Urinary tract infection (CD II) was the commonest adverse event (12.5%).

Conclusion:

Paediatric URS can be delivered in the setting of a regional centre without compromising outcomes. This includes when carried out by adult endourologists, without routine pre-stenting and omitting use of ureteric access sheath.
Immunogenicity of SARS-CoV-2 vaccines in patients with breast cancer
Authors: Denault Elyssa , Nakajima Erika , Naranbhai Vivek , Hutchinson Jennifer A. , Mortensen Lindsey , Neihoff Elizabeth , Barabell Caroline , Comander Amy , Juric Dejan , Kuter Irene , Mulvey Theresa , Peppercorn Jeffrey , Rosenstock Aron S. , Shin Jennifer , Vidula Neelima , Wander Seth A. , Moy Beverly , Ellisen Leif W. , Isakoff Steven J. , Iafrate A. John , Gainor Justin F. , Bardia Aditya , Spring Laura M.
Published: August 2022

Purpose:

To explore the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with breast cancer based on type of anticancer treatment.

Methods:

Patients with breast cancer had anti-spike antibody concentrations measured ⩾14 days after receiving a full SARS-CoV-2 vaccination series. The primary endpoint was IgA/G/M anti-spike antibody concentration. Multiple regression analysis was used to analyze log10-transformed antibody titer concentrations.

Results:

Between 29 April and 20 July 2021, 233 patients with breast cancer were enrolled, of whom 212 were eligible for the current analysis. Patients who received mRNA-1273 (Moderna) had the highest antibody concentrations [geometric mean concentration (GMC) in log10: 3.0 U/mL], compared to patients who received BNT162b2 (Pfizer) (GMC: 2.6 U/mL) (multiple regression adjusted p = 0.013) and Ad26.COV2.S (Johnson & Johnson/Janssen) (GMC: 2.6 U/mL) ( p = 0.071). Patients receiving cytotoxic therapy had a significantly lower antibody titer GMC (2.5 U/mL) compared to patients on no therapy or endocrine therapy alone (3.0 U/mL) ( p = 0.005). Patients on targeted therapies (GMC: 2.7 U/mL) also had a numerically lower GMC compared to patients not receiving therapy/on endocrine therapy alone, although this result was not significant ( p = 0.364). Among patients who received an additional dose of vaccine ( n = 31), 28 demonstrated an increased antibody response that ranged from 0.2 to >4.4 U/ mL.

Conclusion:

Most patients with breast cancer generate detectable anti-spike antibodies following SARS-CoV-2 vaccination, though systemic treatments and vaccine type impact level of response. Further studies are needed to better understand the clinical implications of different antibody levels, the effectiveness of additional SARS-CoV-2 vaccine doses, and the risk of breakthrough infections among patients with breast cancer.
Educated into Sinophilia? How Kazakh Graduates/Students of Chinese Universities Perceive China
Authors: Arynov Zhanibek
Published: August 2022

This article examines perceptions of China and contributes to the ongoing academic debate on Sinophobia in Central Asia. However, unlike existing studies, it specifically focuses on perceptions of those, who have first-hand China experience – Kazakh students/graduates of Chinese universities. Based on in-depth interviews with them, the article argues that those with first-hand China experience tend to reject the China threat theory, found to be widespread among the general population. Instead, China-educated Kazakh youth perceive China mostly as an economic opportunity for their own country. Yet, this does not necessarily make them Sinophiles in the sense that they still express certain concerns related to their country’s potential over-dependence on China. But more interestingly, they see China as the “civilizational other.” This perceived civilisational abyss even among the more-informed segments of the population appears to be one of the main causes of the alienation of China and the Chinese in Kazakhstan.
Maternity Healthscapes: Conceptualization and Index Development
Authors: Martens Carmen , Delcourt Cécile , Petermans Ann
Published: August 2022

Objectives:

This article provides a conceptualization and an index of the multidimensional concept of maternity healthscapes (MHS).

Background:

Healthscape has emerged as a potential key aspect to improve patient experience. Surprisingly, there has been little effort to delineate the concept of MHS from a design perspective, while maternity wards have unique characteristics and particular challenges. Indeed, patients in maternity wards are usually not acutely ill but can feel highly vulnerable due to the pain, stress, and the many uncertainties surrounding labor and delivery—which can heighten patients’ need for intimacy, supporter comfort, and additional supporting services. Thus, healthscapes need to be designed to account for the specificities of childbearing and needs of those patients and their family.

Methods:

A multidisciplinary literature review and 39 in-depth interviews were conducted with various stakeholders—mothers, midwives, heads of midwives, and chief executives.

Results:

The authors develop a conceptualization to establish a comprehensive understanding of the dimensionality of MHSs. Based on that comprehensive conceptualization, the authors develop an index providing a census of the aspects in the MHS that various stakeholders—such as healthcare providers, designers, and architects—should take into account when conceiving MHS.

Conclusions:

Healthcare providers, designers, and architects can use this conceptualization and index to closely monitor and measure for evaluations and further improvements of the MHS, thereby enhancing patient experience in maternity wards.
Biological Effects of High Tibial Osteotomy on Spontaneous Osteonecrosis of the Knee
Authors: Kumagai Ken , Yamada Shunsuke , Nejima Shuntaro , Sotozawa Masaichi , Inaba Yutaka
Published: August 2022

Objective

The purpose of this study was to evaluate the postoperative status of spontaneous osteonecrosis of the knee (SONK) after high tibial osteotomy (HTO) with concomitant bone marrow stimulation (BMS) using synovial fluid (SF) biomarkers.

Design

Twenty patients with SONK who underwent opening wedge HTO were enrolled. Paired SF samples from the affected knee were collected at the time of HTO surgery and at the time of plate removal. SF concentrations of interleukin (IL)-6, IL-8, and matrix metalloproteinase (MMP)-13 were measured by enzyme-linked immunosorbent assays. The Knee Society Score (KSS) and hip-knee-ankle (HKA) angle were assessed before and 2 years after HTO.

Results

The KSS knee and function scores were significantly improved after HTO (mean changes of 33.8 and 29.4, respectively). The mean HKA angle was changed from mechanical varus (−8.6°) to valgus (5.2°). Concentrations of IL-6, IL-8, and MMP-13 were significantly decreased after HTO (mean changes of −73.7%, −32.4%, and −47.9% from preoperative baseline, respectively). Significant correlations were found between lesion size and concentrations of biomarkers, except for preoperative MMP-13.

Conclusions

SF levels of biomarkers of inflammation and cartilage degradation were reduced after HTO with a concomitant BMS procedure, suggesting a biological improvement in SONK.
Prevalence and global trends of polypharmacy among people living with HIV: a systematic review and meta-analysis
Authors: Danjuma Mohammed I. , Adegboye Oyelola A. , Aboughalia Ahmed , Soliman Nada , Almishal Ruba , Abdul Haseeb , Mohamed Mohamad Faisal Hamad , Elshafie Mohamed Nabil , AlKhal Abdulatif , Elzouki Abdelnaser , Al-Saud Arwa , Chaponda Mas , Bidmos Mubarak Arriyo
Published: August 2022

Background:

There has been a rising prevalence of polypharmacy among people living with HIV (PLWH). Uncertainty however remains regarding the exact estimates of polypharmacy among these cohorts of patients.

Methods:

We conducted a systematic search of PubMed; EMBASE, CROI, Cochrane Database of Systematic Reviews; Science Citation Index and Database of Abstracts of Reviews of Effects for studies between 1 January 2000 and 30 June 2021 that reported on the prevalence of polypharmacy (ingestion of > 5 non-ART medications) among PLWH on antiretroviral therapy regimen (ART). Prevalence of polypharmacy among HIV-positive patients on ART with Clopper–Pearson 95% confidence intervals were presented. The heterogeneity between studies was evaluated using [Formula: see text] and [Formula: see text] statistics.

Results:

One hundred ninety-seven studies were initially identified, 23 met the inclusion criteria enrolling 55,988 PLWH, of which 76.7% [95% confidence interval (CI): 76.4–77.1] were male. The overall pooled prevalence of polypharmacy among PLWH was 33% (95% CI: 25–42%) ( I2 = 100%, τ2 = 0.9170, p < 0.0001). Prevalence of polypharmacy is higher in the Americas (44%, 95% CI: 27–63%) ( I2 = 100%, τ2 = 1.0886, p < 0.01) than Europe (29%, 95% CI: 20–40%) ( I2 = 100%, τ2 = 0.7944, p < 0.01).

Conclusion:

The pooled prevalence estimates from this synthesis established that polypharmacy is a significant and rising problem among PLWH. The exact interventions that are likely to significantly mitigate its effect remain uncertain and will need exploration by future prospective and systematic studies.

Registration:

PROSPERO: CRD42020170071

Plain Language Summary

Background: In people living with HIV (PLWH), what is the prevalence of polypharmacy and is this influenced by sociodemographic factors? Methods and Results: In this systematic review and meta-analysis of 23 studies comprising 55,988 participants, we have for the first time found an estimated polypharmacy pooled prevalence of 33% among PLWH. There was a relatively higher pooled prevalence of polypharmacy among the America’s compared with European cohorts of PLWH. Conclusion: Polypharmacy among PLWH is a rising morbidity that needs urgent intervention both at policy and patient levels of care.
Programming learning and teaching of pre-service computer science teachers: Challenges, concerns, and solutions
Authors: Gökoğlu Seyfullah , Kilic Servet
Published: August 2022

This study investigates pre-service computer science (CS) teachers’ perspectives on the factors affecting their programming abilities, concerns about their future professional lives, and pedagogical suggestions for effective programming teaching. The participants of the study were twenty-eight pre-service CS teachers studying at eighteen different universities in Türkiye. The data was gathered with a questionnaire consisting of open-ended questions. Results showed that inherent programming challenges, personal factors, and quality of undergraduate education affected pre-service CS teachers’ abilities in programming teaching. They were concerned about their professional lives relating to programming teaching, keeping up with technological innovations, pedagogical concerns, and teaching practice. They also suggested pedagogical approaches that could be used in programming teaching under two categories, namely basic programming teaching, and teaching principles and techniques. The study contributes to the development of programming teaching by shedding light on the current perspectives of pre-service CS teachers on programming education.
Patient experiences of remote care in a pain service during a pandemic
Authors: Willcocks Cathy , Joy Deborah LA , Seward Joseph , Mills Samantha , Heywood Mark , Price Cathy
Published: August 2022

Background

In March 2020, Pain Management Services were obliged to cease face-to-face consultations. This abrupt change, in line with recommendations from the British Pain Society, aimed to protect patients and staff and allowed resource re-allocation. Pain services were obliged to switch to remote consultations using Video Tele-Conferencing Technology (VTC) and Remote Consultations (RC) either through telephone or video calls using a variety of media and software applications. Little is known about the patient experience of remotely delivered pain care especially when alternatives are removed. The aim of this work was to understand the patient experience of this necessary switch regarding pain self-management interventions during the initial stages of the COVID-19 pandemic.

Methods

A mixed-methods evaluation of the patient experience from three pain self-management interventions, taking place in a large community-based pain rehabilitation service along the South Coast of England, was performed. Experience-Based Design (EBD) methods were used to map patient experience at touch points through two interventions that were delivered in a structured format. Semi-structured recorded interviews were transcribed and analysed using thematic analysis for the third.

Findings

Fifty-eight patients took part covering the scope of the service. In general, educational and psychological sessions were well received, with physical rehabilitation components being less easy to convey remotely. Attrition rates were high for the pain management programme. Group pain education worked particularly well in an online format with hope being the predominant emotion experienced. Clear limitations were technical failures and the lack of ability to form relationships in a virtual world.

Conclusions

Remote digitalised interventions were acceptable to most patients. Attention should be paid to access and improving social aspects of delivery when considering such interventions. Physiotherapy may require more face-to-face necessitating a hybrid model and needs further investigation. EBD proved a highly suitable approach.
Ortner’s syndrome: A rare case of hoarseness secondary to chronic aortic dissection
Authors: Hammad Nour , Jabri Ahmad , Shahrori Zaid , Haddadin Faris , Nasser Farhan , Balakumaran Kathir , Kondapaneni Meera , Heffernan Jeremy , Marshall Michael
Published: August 2022

Ortner’s syndrome, also known as cardiovocal syndrome, is a rare presentation of aortic dissection. Symptoms occur as a result of recurrent laryngeal nerve compression. Our report describes a case of a patient who complained of hoarseness for a few months and was eventually diagnosed with chronic aortic dissection.
The Black Podcaster-Scholar: A Critical Reflection of Using Podcasting as Methodology as a Black Doctoral Student
Authors: Smith Ariel D.
Published: August 2022

I am a Black woman, a doctoral candidate, and a podcaster. In every facet of those identities, I have been worried about my voice. As a young child, teachers pushed me to sound “collegiate” and not “ghetto” so I could impress our private Christian school’s predominantly White and male board of directors. My graduate and doctoral programs led me to challenge and critique previous ideologies around voice and audience, while also perpetuating gatekeeping via academic jargon. Podcasting became a way for me to resist falling into the social norms of voice in the academy, but not without confronting challenges the industry itself carried around voice as well as my own insecurities. Beyond a text replacement and a way for doctoral students and faculty to widen their audience and build a brand, podcasting in the academy should be recognized as a critical reflective praxis for scholars that centers the voices of those that often go silenced or ignored. This article is a critical reflection of my methodological use of podcasting to resist data collection norms and traditional research boundaries in the academy while also confronting my own internalized anti-Blackness surrounding Black sonic existence.
The New Normal: Exploring Heterosexual Consumers’ Responses to Lesbian and Gay-Themed Adverts in South African Mainstream Media
Authors: Polkinghorne Robert , Madinga Nkosivile Welcome , Broster Philip , Kappatos Andrianna , Kirr Julia , Kader Junaid , Mophethe Chandra , Joseph Aparna , Roodt Sebastian
Published: August 2022

Lesbian and gay-themed advertising hold great potential for marketers and brands, yet an understanding of how these advertisements influence heterosexual consumers is still a question of debate. This study examined the developmental factors and traditional culture of consumers, which are critical in understanding tolerance of homosexuality. It further examined the impact of tolerance of homosexuality on attitudes toward lesbian and gay-themed advertisements and brands. Primary data were collected through an electronic self-administered questionnaire, and 690 responses from heterosexual consumers were recorded. The data were analyzed using the Partial Least Squares Structural Equation Modeling (PLS-SEM). The findings indicate that heterosexual consumers with a high tolerance toward homosexuality have more positive attitudes toward lesbian and gay-themed adverts and brands. In addition, advertisement themes (gay vs. lesbian) had no significant effect on consumer attitudes toward the advertisement as well as toward the brand. These findings provide guidelines for future research and implications for advertisers who intend to address consumers of various sexual orientations.
Leverage and Investment Cash Flow Sensitivity: Evidence from Muscat Securities Market in Oman
Authors: Yilmaz Ilker
Published: August 2022

This article investigates the investment cash flow sensitivity (ICFS) and the effect of leverage on the firms’ ICFS by using data from 66 non-financial companies from Muscat Securities Market, Oman for a 7-year period from 2013 to 2019. We used a dynamic panel investment model based on the Euler equation approach and ran dynamic panel regressions using the dynamic panel system generalized method of moments (GMM). We run two regressions: first, testing the sensitivity of investment to the availability of the internal funds; second, testing the effect of firms’ leverage levels on the sensitivity of investment to cash flows. The results showed a significant sensitivity of investment to cash flows for the sample companies. The positive coefficient for the cash flow variable indicates the presence of financing constraints. The results showed that leverage has a significant effect on the ICFS of the companies, indicating that the companies with higher leverage have ICFS.
“Protecting my Positivity”: Emerging Adults as Social Media Actors, Agents, and Authors
Authors: Naudé Luzelle
Published: August 2022

Social media engagements are integral to the lives and experiences of emerging adults. The aim of this study was to explore social media as a space where South African emerging adults shape and refine their sense of self. An explorative and descriptive qualitative approach was employed and individual interviews were conducted with 41 participants ((MAge= 23.17; SD = 2.65; Females = 53.7%). Data were analysed using thematic analysis. Participants confirmed the centrality of social media in their lives and emphasised both the value (being connected, informed, and entertained) and the dangers (invasion of time/privacy and exposure to negativity/inauthenticity) of social media engagements. Social media facilitate the development towards an evolving story of the self as emerging adults navigate through the intricacies of life. A prominent finding in this study related to the intentionality of the social media engagements of emerging adults as they actively attempt (as Actors, Agents, and Authors) to find positivity and possibility in a world of contradiction and instability.
Think Happy Be Happy: Salesperson’s Personal Happiness and Flourishing
Authors: Kuanr Abhisek , Lyngdoh Teidorlang , Guda Sridhar , Pradhan Debasis
Published: August 2022

Although the role of positive emotions is important in sales, personal happiness remains understudied in the selling context. Grounded in broaden-and-build theory, this study aims to examine the relationships among personal happiness, job involvement, job satisfaction and salesperson flourishing. For salespeople, the new demands of a connected world have largely blurred the boundaries between their personal life and work life. It has allowed emotions from their personal life to spill over into their workplace. Data from 137 salespeople in the retail context in India lend support for the proposed serial mediation model. The authors propose that the influence of personal happiness on a salesperson flourishing is mediated by job involvement and job satisfaction. Results of this study shows that personal happiness has a direct influence on the salesperson’s flourishing and is effective only through the mediating influence of job satisfaction and not of job involvement. This study extends the broaden-and-build theory by proposing that personal happiness may influence flourishing at work. The findings illustrate the need for a renewed focus on salesperson’s personal emotions, especially in todays connected workplace where the boundaries between personal and work life are shrinking