bluuebunny/crossref_metadata_2025 huggingface dataset:
Health Behavior and Medication Adherence in Hypertensive Client
Authors: Wiarsih Wiwin , Jannah Nurul Miftahul , Sahar Junaiti
Published: May 2020

Hypertension as Non-Communicable Diseases (NCD) is the largest contributor to the causes of death in the world. Complications of hypertension account for the majority of deaths globally. Uncontrolled health behavior in patients with hypertension is closely related to an increase in morbidity rates due to complications from hypertension each year. Medication adherence is one of an effort to form positive health behaviors to prevent hypertension complications. This study aims to identify the relationship between health behavior with medication adherence in hypertensive clients in Cipayung District, East Jakarta. This study using cross sectional design, approach with 109 participants, who were selected by purposive sampling, are choosen primary hypertensive clients of middle adulthood. The results of the chi square test showed that there was a relationship between health behavior and medication adherence (p value: 0.024) 90% CI. The results of the study it can be concluded that the more positive the health behavior, the higher the adherence to taking medication in hypertensive clients. Community nurses have an important role in modifying the behavior of hypertensive patients with a variety of approaches both as individuals, families, and the public can maintain their health well-being.

Keywords: hypertension; health behavior; medication adherence
Suicide Notes: Exaggerations by Males and Females
Authors: Kusumastuti Purbo , Apriana Aulia , Basthomi Yazid
Published: May 2020

Touching into the gender differences between males and females in expressing the use of exaggeration expressions, this study analyzes the relevant data using the LIWC tool, the HIP method, and the deficit and difference theories. This study found that in relation to the gender stereotypes, both males and females speak differently, yet also demonstrate similarities. Both the male and female subjects express emotions equally in the language production; yet, the negative emotions are dominated by the males, and the positive emotions are dominated by the females. The difference of emotion productions influences the differences in the males’ production of exaggeration expressions, such as empty adjectives, italic expressions, and hyperbole by the female subjects.
Upaya Mencegah Kekambuhan ODGJ melalui Peran Kader Kesehatan Jiwa di RSJD Dr Amino Gondohutomo Provinsi Jawa Tengah
Authors: PH Livana , Kandar Kandar , Sudiyanto Slamet
Published: May 2020

Orang dengan Gangguan Jiwa atau disebut ODGJ masih menjadi stigma di masyarakat, tentunya hal ini akan membuat ODGJ dan keluarga menjadi tidak nyaman, sehingga kekambuhan ODGJ tidak hanya karena putus obat namun karena perilaku masyarakat terhadap ODGJ. Upaya untuk mencegah kekambuhan ODGJ tidak hanya menjadi tugas keluarga tetapi juga masyarakat. Tujuan dilakukan pengabdian masyarakat ini yaitu untuk mengevaluasi kemampuan kader kesehatan jiwa dalam mejalankan perannya di masyarakat. Kegiatan ini dilaksanakan di RSJD Dr Amino Gondohutomo Provinsi Jawa Tengah. Peserta dalam kegiatan ini adalah kader kesehatan jiwa yang berada di lingkungan RSJD Dr Amino Gondohutomo Provinsi Jawa Tengah yang berjumlah 48 orang. Kegiatan dilaksanakan pada 30 Januari 2020. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan kader dalam mencegah kekambuhan ODGJ.
 Kata kunci: kekambuhan; ODGJ; kader kesehatan jiwa
 FORUM GROUP DISCUSSION AS AN EFFORT TO PREVENT ODGJ RECURRENCE THROUGH THE ROLE OF SOUL HEALTH CARE IN RSJD DR AMINO GONDOHUTOMO CENTRAL JAVA PROVINCE
 ABSTRACT
People with mental disorders or so-called ODGJ are still a stigma in the community, of course this will make ODGJ and family uncomfortable, so ODGJ recurrence is not only due to drug withdrawal but because of community behavior towards ODGJ. Efforts to prevent ODGJ recurrence are not only a duty of the family but also the community. The purpose of this community service is to evaluate the ability of mental health cadres in carrying out their role in the community. This activity was carried out at Dr Amino Gondohutomo Central Java Province, Central Java. Participants in this activity were mental health cadres who were in the environment of Dr. Amino Gondohutomo Central Java Province, totaling 48 people. The activity was carried out on 30 January 2020. The results of the activity showed an increase in cadre knowledge in preventing ODGJ recurrence.
 Keywords: recurrence; ODGJ; mental health cadre
Hubungan Motivasi dengan Perilaku Swamedikasi
Authors: Efayanti Erina , Susilowati Tri , Imamah Ida Nur
Published: May 2020

Swamedikasi adalah upaya pengobatan diri sendiri, biasanya dilakukan untuk mengatasi penyakit ringan, seperti demam, nyeri, pusing, batuk, influenza, diare, penyakit kulit. Badan Pusat Statistik  mengatakan bahwa masyarakat Indonesia yang melakukan swamedikasi sebesar 72,44%. Penelitian bertujuan untuk mengetahui hubungan motivasi dengan perilaku swamedikasi di Apotek Suganda Tangen Sragen. Penelitian analitik dengan rancangan penelitian cross sectional. Pengambilan sampel menggunakan tekhnik quota sampling dengan jumlah 90 responden, dengan subjek penelitian ini adalah pembeli yang membeli obat tanpa menggunakan resep dari dokter di Apotek Suganda Tangen Sragen, sedangkan instrument penelitian ini menggunakan kuesioner, analisa bivariate menggunakan uji Chi Square dengan taraf signifikasi (0,05). Hasil analisa univariate sebagian besar responden memiliki motivasi yang tinggi sebanyak 42 responden(46,7%), perilaku swamedikasi menunjukkan sebagian besar responden memiliki perilaku yang baik sebanyak 38 responden (42,2%). Hasil analisa bivariate menunjukkan nilai Exact Sig. (2-sided) (0,000) < 0,05. Terdapat hubungan motivasi dengan perilaku swamedikasi di Apotek Suganda Tangen Sragen.

 

Kata kunci : motivasi, perilaku, swamedikasi

 

RELATIONSHIP OF MOTIVATION WITH THE BEHAVIOR OF SELF MEDICATION

 

                                                                ABSTRACT

Self-medication is an attempt self-medication, usually done to cope with minor illnesses, such as fever, pain, dizziness, cough, influenza, diarrhea, skin diseases.The Central Statistics Agency said that the Indonesian people who self-medication were 72,44%. The purpose of relationship of motivation with the behavior of self-medicationat theSugandaPharmacy Tangen Sragen.  Analytical research with cross sectional research design. Sampling using the dwarf quota sampling with a population of 90 respondents, with the subject of the research is the buyer who bought drugs without the use of a prescription from a Medical Doctor at theSuganda Pharmacy Tangen Sragen, while this research instrument using bivariate analysis questionnaires, using test Chi Square with the significance level (0.05). The results of the univariate analysis most respondents have a high motivation as much as 42 respondents (46,7%), behavioural self-medication showed most respondents have good behavior as much as 38 respondents (42.2%). Bivariate analysis results show the Exact value of the Sig (2-sided) (0.000) < 0.05. There is a relationship of motivation with the behavior of self-medicationat theSuganda Pharmacy Tangen Sragen.

 

Keywords: motivation, behavior, self-medication
Peningkatan Pengetahuan Kader tentang Deteksi Dini Kesehatan Jiwa melalui Pendidikan Kesehatan Jiwa
Authors: Febrianto Terri , PH Livana , Indrayati Novi
Published: May 2020

Kesehatan jiwa adalah kondisi dimana seorang individu dapat berkembang secara fisik, mental, spiritual, dan sosial sehingga individu tersebut menyadari kemampuan yang dimiliki, dapat megatasi tekanan, dapat bekerja secara produktif, dan mampu memberikan kontribusi untuk komunitasnya. Kondisi perkembangan yang tidak sesuai pada individu disebut gangguan jiwa. Pendidikan kesehatan jiwa merupakan upaya untuk mempengaruhi atau mengajak orang lain baik individu, kelompok, atau masyarakat agar melaksanakan perilaku sehat jiwa. Kemampuan masyarakat dapat ditingkatkan melalui pendidikan kesehatan khususnya mendeteksi dini masalah kesehatan jiwa. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross sectional , sampel yang digunakan sebanyak 62 responden dengan teknik sampling Purposive Sampling. Penelitian ini menunjukkan usia kader kesehatan jiwa di Desa Banyutowo mayoritas berusia 47 tahun. Mayoritas responden adalah perempuan 72,6%,  dan mayoritas ekerjaan responden adalah wiraswasta 90,3%. Hasil uji wilcoxon didapatkan nilai signifikan dengan p value 0,000 < 0,05, yang artinya terdapat pengaruh signifikan dari tingkat pengetahuan kader sebelum dan sesudah diberikan pendidikan kesehatan deteksi dini kesehatan jiwa

 

Kata kunci: pendidikan kesehatan, kesehatan jiwa, pengetahuan, kader

 

ABSTRACT

Mental health is a condition where an individual can develop physically, mentally, spiritually, and socially so that the individual is aware of his abilities, can overcome stresses, can work productively, and be able to contribute to his community. Development conditions that are not suitable for individuals are called mental disorders. Mental health education is an attempt to influence or invite other people, individuals, groups, or communities to carry out healthy mental behaviors. Community capacity can be improved through health education, especially early detection of mental health problems.This study is a quantitative study with a cross sectional approach, with 62 respondents using the Pourposive Sampling sampling technique. This study shows that the majority of mental health cadres in Banyutowo Village are 47 years old. The majority of respondents were women 72.6%, and the majority of respondents were 90.3% self-employed. The results of the Wilcoxon test obtained a significant value with p value 0,000 <0,05, which means that there was a significant influence on the level of knowledge of cadres before and after being given mental health early detection health education in Banyutowo Kendal Village. To the next researcher, it is expected to be able to carry out further research to find out the factors that influence people's disinterest in becoming health cadres and are expected to pay attention to the situation that will be examined and understand the condition of the community.

 

Keywords: health education, mental health, knowledge, cadre
Efek Mangiferin dalam Mengatasi Masalah Kesehatan
Authors: Permata Elin Indah , Khoirunnisa Yustisya
Published: May 2020

Masalah kesehatan terbesar di dunia disebakan oleh penyakit tidak menular seperti penyakit jantung,  kanker, penyakit pernapasan, dan diabetes melitus. Prevalensi penyakit tidak menular lebih tinggi pada negara yang berpenghasilan rendah serta menengah daripada negara yang berpenghasilan tinggi. Berbagai pengobatan dilakukan untuk mengatasi penyakit tersebut seperti penggunaan obat oral. Namun, beberapa obat memiliki efek samping tertentu yang mengakibatkan penyakit lain. Pengobatan alternatif yang dilakukan yaitu menggunakan pengobatan herbal yang didapatkan dari tanaman. Salah satu tanaman yang memiliki potensi herbal yaitu Mangga (Mangifera) yang memiliki kandungan senyawa mangiferin. Senyawa tersebut memiliki efek farmakologi yang dapat dijadikan obat untuk penyakit tersebut.  Tujuan review ini untuk menjelaskan efek Mangiferin sebagai terapi masalah kesehatan terutama pada penyakit tidak menular pada penelitian sebelumnya. Review ini disusun dengan melakukan penulusuran artikel melalui database NCBI dan Google Scholar. Hasil dari penelusuran artikel yang ditemukan yaitu Mangiferin memiliki efek  antikanker, antiinflamasi, antidiabetes, antioksidan dan kardioprotektor yang dapat dijadikan terapi untuk mengatasi berbagai masalah kesehatan. Saran untuk dunia penelitian lebih dikembangkan lagi mengenai potensi tanaman herbal terutama buah mangga sehingga dapat digunakan sebagai pengobatan.

 

Kata Kunci: mangga, mangiferin, efek farmakologi

 

EFFECT OF MANGIFERIN ON OVERCOMING HEALTHY PROBLEMS

                        

                                                                ABSTRACT

The biggest health problem in the world is caused by non-communicable diseases such as heart disease, cancer, respiratory disease, and diabetes mellitus. The prevalence of non-communicable diseases is higher in countries with low and middle income than countries with high income. Various treatments are carried out to overcome the disease such as the use of oral drugs. However, some drugs have side effects that cause other diseases. Alternative medicine is carried out using herbal treatments obtained from plants. One of the plants that has herbal potential is Mango (Mangifera) which contains mangiferin compounds. These compounds have pharmacological effects that can be used to treatment the disease. This review article aims to explain the effects of Mangiferin as a therapy for health problems, especially in non-communicable diseases in previous studies. The method used in this article is through searching articles through the NCBI database and Google Scholar. The results of an article search found that Mangiferin has anticancer, anti-inflammatory, antidiabetic and antioxidant effects that can be used as therapies to treat a variety of health problems. Suggestion for all researchers is more developed about the potential of herbal plants especially mangoes so that it can be used as a treatment.

 

Keyword : mango (mangifera), mangiferin,  pharmacological effect
Potensi Susu Kedelai sebagai Anti Hipertensi
Authors: Syarpia Reginda Dwi , Kurniati Karin Indah
Published: May 2020

Individu dengan hipertensi memiliki peningkatan risiko penyakit kardiovaskular aterosklerotik, karena hipertensi berkontribusi terhadap disfungsi endotel dan meningkatkan ekspresi molekul adhesi sel. Pangan fungsional mempunyai fungsi dalam peningkatan kesehatan dan pencegahan penyakit. Kedelai merupakan salah satu jenis pangan fungsional yang mengandung zat­zat gizi seperti isoflavon, saponin, lesitin dan fitosterol yang dapat menurunkan risiko penyakit kardiovaskular.Penelitian ini adalah studi literature review dan sumber pustaka yang digunakan melibatkan 15 pustaka yang berasal dari 4jurnal nasional dan 11 jurnal internasional.Tujuan dari literature review ini adalah untuk mengetahui pengaruh susu kedelai terhadap penurunan tekanan darah pada penderita hipertensi karena susu kedelai sangat mudah didapatkan di Indonesia sehingga dapat memberikan informasi bagi masyarakat luas. Berbagai penelitian menunjukkan hasil yang cukup signifikan mengenai pengaruh susu kedelai terhadap penurunan tekanan darah pada penderita hipertensi. Isoflavon dalam kedelai dapat mengurangi peningkatan tekanan darah melalui berbagai mekanisme misalnya percepatan produksi NO dan penghambatan inflamasi.

 Kata kunci: isoflavon, hipertensi, susu kedelai

 POTENTIAL OF SOYBEAN MILK AS ANTI-HYPERTENSION

 ABSTRACT

Individuals with hypertension have an increased risk of atherosclerotic cardiovascular disease, because hypertension contributes to endothelial dysfunction and increases the expression of cell adhesion molecules. Functional food has a function in improving health and preventing disease. Soybean is one type of functional food that contains nutrients such as isoflavones, saponins, lecithin and phytosterols which can reduce the risk of cardiovascular disease. This research is a literature review study and literature sources used involved 15 libraries originating from 4 national journals and 11 international journals. The purpose of this review literature is to determine the effect of soy milk on reducing blood pressure in patients with hypertension because soy milk is very easy to obtain in Indonesia so that it can provide information to the wider community. Various studies have shown significant results regarding the effect of soy milk on reducing blood pressure in people with hypertension. Isoflavones in soy can reduce blood pressure increases through various mechanisms such as accelerated NO production and inhibition of inflammation.

 Keywords: isoflavones, hypertension, soymilk
Scientific research of the SI “Institute of Nuclear Medicine and Diagnostic Radiology of NAMS of Ukraine” in 2019: high-technology and breakthrough trends
Authors: Dykan Iryna , Tarasyuk Boris , Andrushchenko Irina
Published: May 2020

Institute’s areas of work: research in the field of radiation diagnostics and nuclear medicine; reference examination with high-tech methods of radiation diagnostics; introduction of new diagnostic approaches into practice; specialty training of doctors in the field of radiology and ultrasound diagnostics; methodological work to improve research and training programs in radiation diagnostics in Ukraine. Directions of the Institute's scientific activities in 2019: the study of diagnostic images’ heterogeneity in the differential diagnosis of malignant neoplasms; criteria development for the differential diagnosis of congenital and acquired liver diseases in children; development of urgent, detailed ultrasound examinations for traumatic injuries of the human body, complex radiation investigation of the wound channel in case of gunshot injuries. List of promising research topics identified in accordance with world trends: Prediction of the breast and prostate cancer progression based on the analysis of MRI and ultrasound images. Prediction of the ischemic stroke, hemorrhagic stroke, multiple sclerosis progression based on the analysis of MRI images. Visualization of the pharmacodynamic action and tropism of drugs. Highlight and study surrogate radiological markers of aging and longevity. To study the radiological semiotics of therapeutic windows at ischemic stroke, hemorrhagic stroke and cancer. Research in the field of cognitology.
Charged particles therapy in radiation oncology
Authors: Dzhuzha Dmitry
Published: May 2020

The physical and biological features of using protons and heavy ions in the treatment of malignant tumours were reviewed. It is showed that proton therapy is an effective method for treatment of malignant tumours, which has certain benefits comparing photon therapy. This modality may be recommended to 10-15 % of oncological patients. Carbon ion radiation therapy is especially perspective as it has local relative biological effectiveness till 2,0-3,5. The clinical efficacy of charged particles therapy at most expansive tumours was revealed. The cost efficacy of this type of radiation therapy was given.
Key words: proton therapy, ion therapy, charged particles therapy, clinical efficacy of charged particles therapy.
Clinical case: conservative treatment of sequestered disc herniation
Authors: Afanasyeva Inna , Andrushchenko Iryna , Bezghodov Taras
Published: May 2020

The literature has a lot of descriptions of the spontaneous disappearance of herniated discs. This article presents a clinical case of conservative treatment of sequestered disc herniation applying a complex of drug treatment and kinesitherapy. After 5 months a positive trend was observed against the background of conservative treatment. A year later, there was a lack of clinical symptoms and, according to MRI, and positive dynamics in the form of a decrease in the caudal sequestration of L5-S1 to symmetrical circular protrusion (hollow capsule effect).
Key Words: sequestered disc herniation, drug treatment, kinesitherapy, MRI.
Analysis of the Evolution of Hazardous Chemical Waste from Medicolegal Activities
Authors: Fulga Ana , Perju-Dumbrava Dan , Ciubara Anamaria , Musat Carmina Liana , Mereuta Claudiu , Bulgaru-Iliescu Andra Irina , Ciubara Bogdan Alexandru
Published: May 2020

The paper presents an analysis of the management of hazardous chemical waste from medicolegal. activities. The analysis is based on eight years survey of the hazardous chemical waste management, ponting out the current procedures. The time series analysis is used to predict the evolution of such medical waste, and according to the forecast some strategic objective for reducing the amount of chemical waste are proposed.
Nenitzescu Indole Synthesis: 1929-2019 Unexpected Formation of a Pyrrole-Azepine Hybrid in the Nenitzescu Indole Synthesis: A Reinvestigation
Authors: Ivan Beatrice Cristina , Caira Mino Rodolfo , Dumitrascu Florea
Published: May 2020

The condensation of 1,4-benzoquinones with enamines reported ninety years ago is a name reaction known as the Nenitzescu indole synthesis which has proved to be a very useful method for obtaining both 5-hydroxyindoles and nonindole derivatives. An unexpected compound containing two condensed azepine rings was isolated in 1988 from the reaction between 1,4-benzoquinone and ethyl 3-aminocinnamate performed in 1-butanol. The reinvestigation of the proposed bisazepine structure by X-ray analysis revealed instead a pyrrole-azepine hybrid having the two heterocycles rings connected by a double bond.
Pakistan�s Timberline Forest Ecosystem Dynamics vis-a-vis Changing Climate Across Three Provinces (KPK, AJK and GB) Using GIS/RS Techniques
Authors: Mahmood Tariq , Mirza Sarwat Naz , Gulzar Saeed , Hanif Mohammad
Published: May 2020

World`s forests have always been under anthropogenic threats leading to instantaneous and sound supervision using satellite-based data collecting capabilities through GIS/RS. Timber line in Pakistan consists of sub-alpine forests and alpine pastures of KPK, AJK and GB. Research findings showed that earth`s climate was changing rapidly than previously assumed, demanding the spatio-temporal dynamics analysis using GIS/RS techniques in prevalent climate change scenarios. Two separate methods were used; 1) Visual Interpretation of Supervised Classification Technique for AJK & GB and 2) object Oriented Classification of Supervised Classification Technique for KPK. The primary data for T (max), T (min) & Ppt. (1980-2013) was taken from PMD, Islamabad. Province wise data showed 15 % change in forest cover area for timber line in both KPK (142780 Ha) & AJK (24990 Ha), followed by GB (39267 Ha) as13 % across 2005-2014. The results calculated that the average upward shift in timberline was highest in KPK (285 m), followed by AJK (233 m) and GB (170m) across 2005-2014.The data also showed change in avg. T (max) was 3.4�, -1.8� and 0.6� C, avg. T (min) was -2�, -1.5� and -2� C while change in total precipitation was 88.5, -3.7 and 75.5 mm for AJK, GB and KPK respectively. The Pearson`s Correlation Co-efficient chart concluded that climatic factors showed a strong and positive correlation among themselves as well as with change in elevation. However, the correlation among climatic factors and change in forest cover area was weak concluding deforestation to be exclusively an anthropogenic phenomena. Change in elevation showed a weak and negative correlation with change in area while all other correlations were non-significant.
Dynamic Rheological Behavior of Chitosan/collagen Mixtures
Authors: Danu Maricel , Simionescu Bogdana , Ibanescu Constanta , Ibanescu Sorin Alexandru
Published: May 2020

Chitosan and collagen are naturally-derived materials with multiple applications, but their mixtures present phase separation phenomena. This shortcoming in relation to the mixture processing and, obviously, the applications can be overcome by choosing the appropriate composition. Rheological methods have been used to study collagen - chitosan mixtures to highlight their compatibility conditions in solution. Through the use of oscillatory rheometry, the viscoelastic behavior of collagen-chitosan mixtures in 0.5M acetic acid solution was analysed. The storage modulus (G`) was used to describe the elasticity of the material, while the loss modulus (G`) provided information on the viscous behavior of the mixtures.
Scientific Investigation of Metal Threads from Medieval Gold Brocaded Velvets by Modern Microanalytical Techniques
Authors: Balta Zizi Ileana , Demetrescu Ioana , Lupu Mihai
Published: May 2020

This study�s aim was to bring to light part of the hidden secrets of some important and valuable historical textiles beautifully adorned with precious metal threads, medieval gold brocaded velvet fragments and court vestments, which are preserved in the treasury collections of some of the most important monasteries and museums in our country. These precious metal thread textiles, includes historical and artistic information, as well as important scientific data regarding the materials and techniques used, their origin, provenience and dating, information that being revealed, have harmoniously blended and intertwined.
Acute Phase Inflammatory Proteins, Gut Microbiota Dysbiosis and Severity of Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus
Authors: Ancusa Oana-Elena , Georgescu Doina , Iurciuc Stela , Georgescu Liviu-Andrei , Basa Norina , Belei Oana , Lighezan Daniel
Published: May 2020

Since obesity and type 2 diabetes mellitus (DM) became almost pandemic, incidence and prevalence of associated nonalcoholic fatty liver disease (NAFLD) rose accordingly. Aim of the study was assessing whether there is a link between circulating C-reactive protein(CRP), gut microbiota dysbiosis and severity of liver disease in patients with NAFLD and confirmed type 2 DM. 50 patients diagnosed with type 2 DM were consecutively enrolled in this cross-sectional, pilot study, being evenly divided in two groups, as matched pairs, on the basis of presence or absence of NAFLD confirmed by abdominal and CT exam, after ruling out a lot of diseases and conditions. Patients underwent measurements of waist circumference, blood pressure (BP), body mass index (BMI) and thoroughly physical examination. Complete blood count (CBC), liver tests, CRP, fasting plasma glucose (FPG), low density lipoprotein(LDL) and high-density lipoprotein(HDL) cholesterol, triglycerides, creatinin and uric acid, micro proteinuria as well as stool microbiology were run, using standardized methods. Fatty liver index (FLI) was also calculated. Fibromax (BioPredictive) was performed in NAFLD (+) patients. NAFLD (+) group displayed significant differences of age and BMI, as well as lab biochemistry: ALT, GGT, LDL-cholesterol and triglycerides, CRP, microprotienuria and stool microbiology.. Strong positive correlation of CRP with gut dysbiosis (DB) severity, microproteinuria, as well as with nonalcoholic steatohepatitis (NASH) score, were observed. DB range correlated positively in NAFLD (+) group with age, BMI, BP, dyspepsia as well as with NASH scores. In conclusion patients with NAFLD and associated type 2 DM displayed a specific profile with significant differences of age, BMI, FLI, diabetic treatment, biochemistry and gut microbiological charts. Strong positive correlations between CRP, gut DB and NASH score suggest the possibility of link between inflammation, gut microbiota DB and severity of liver disease.
Green and Synthetic Metallic Nanoparticles - Obtaining, Characterization and Biological Evaluation in Association with Lupeol
Authors: Bociort Flavia , Cheveresan Adelina , Dragoi Razvan , Heghes Alina , Szuhanek Camelia , Radulescu Matilda , Berceanu-Vaduva Delia , Tischer Alina , Motoc Andrei
Published: May 2020

The field of metal nanotechnology continues to draw the attention of researchers from different areas due to the outstanding properties of nanoparticles. The main aims of this research were to obtain and to study two types of gold nanoparticles; different obtaining pathways (the chemical synthesis and the biosynthesis based on an aqueous extract of lemon balm) were involved in this research. The chemically synthesized nanoparticles were loaded with lupeol. After a preliminary physico-chemical characterization, the compounds obtained were tested in order to evaluate the effects on the viability of colon cancer cells. The formulation of these new gold nanoparticles with average size between 38 and 82 nm, with a good stability against the tendency to form agglomerations according to the Zeta potential values, was confirmed by UV-Vis spectra; the particles containing lupeol have show the best activity against the colon cancer cells.
Malondialdehyde (MDA) as a Marker of Platelet Function in Rats with CCl4-Induced Toxic Hepatopathy
Authors: Iancu Roxana Irina , Toader Paula Mihaela , Mocanu Madalina , Mirestean Camil Ciprian , Iancu Dragos
Published: May 2020

Blood platelets are pivotal cells in the process of hemostasis and thrombosis. In the majority of patients with severe liver disease, platelet function appeared defective. We determinate platelet adhesiveness, aggregability and MDA level, in rats with acute and chronic hepatopathy induced by CCl4 administration. Our data relieves that platelet functions are not only affected in chronic toxic affectation, but also in acute intoxication (p[0.05). Icosanoids production (expressed in MDA levels) are significantly decreased only in chronic CCl4 intoxication (p[0.001). Significant correlation appears between aggregability and MDA (r = -0.78) and adhesiveness and MDA (r = -0.57) in group C, with chronic CCl4 intoxication. The complexity of these platelet functions related to the hepatic disease is still a matter of debate and needs further investigation.
A Study on The Effects of the Absence of Palmaris Longus Tendon on Handgrip Strength of Athletes
Authors: Erdagi Kenan
Published: May 2020

The study aims to find out the incidence of the absence of palmaris longus tendon and to study the effects of the case on handgrip strength of athletes. We studied whether 190 athletes (male n= 80, mean age: 18.9� 2.2; female n= 110, mean age: 18.5� 1.2) included in our study had palmaris longus tendon or not. Then, the handgrip strength values of the athletes were obtained by using a Jamar dynamometer, according to the recommendations of the American Association of Hand Therapists. Total number of participants having no palmaris longus tendon was 59 (31.05%) and it was observed that 37(19.47%) of these individuals didn�t have the tendon in both hands. The number of participants with unilateral tendon absence was 22 (11.5%). The tendon was absent in right hand of 10 individuals (5.26%) and in left hand of 12 individuals (6.31%). After controlling age, height, body weight and body mass index variables of the groups, it was observed that the presence or the absence of palmaris longus tendon in both hands of male athletes didn�t cause any statistical effects on handgrip strength of the athletes. However, left handgrip strength of female athletes with palmaris longus tendon in left hand was found to be higher than left handgrip strength of female athletes with no palmaris longus tendon (p[.01). According to the findings of the study, we might state that the presence or the absence of palmaris longus tendon does not cause a significant effect on handgrip strength of both hands of male athletes (p].05) and that its presence causes a significant effect on left handgrip strength of female athletes (p[.01).
In vitro Study of Different Physicochemical Properties of Root Canal Sealers
Authors: Kerekes-Mathe Bernadette , Szocs Attila-Zsolt , Laszlo Robert , Fazakas Zita , Kovacs Monika , Pop Mihai
Published: May 2020

The ability of root canal sealers to provide apical seal depends on their physicochemical properties. The aim of this study was to investigate and compare physicochemical properties of different root canal sealers. The pH, solubility, dimensional change and flow rate of four commonly used root canal sealers were evaluated. All of the tested sealers showed a significant solubility and dimensional change. The findings of the present study indicated that the calcium-hydroxide based Sealapex has satisfactory physicochemical properties, but from clinical point of view Adseal might be the most suitable for use.
Comparison of Biochemical, Antimicrobial and Cytotoxic Activities of Different Propolis Samples from Malatya and Bilecik
Authors: Keskin Merve , Karlidag Semiramis , Yilmaz Ozgur , Tatlici Eray , Karabulut Ercan , Apohan Elif , Yesilada Ozfer
Published: May 2020

Propolis is a resinous natural mixtures collected and produced by honey bees. It is rich in essential oils and phenolic components so it has high levels of antioxidant, antimicrobial, anti-inflammatory and anti-tumoral activity. In this study the biochemical activity of propolis extracts were determined. The antimicrobial activity and cytotoxic activity of the extracts of the nine different propolis samples were invastigated. Their antimicrobial activities were tested by microdillution metod and define as minimum inhibitory concentration (MIC). Chemical composition of extracts was determined by using GC-MS equipment. Total phenolic content and antioxidant activity of the extracts was measured. Antimicrobial and cytotoxic activity of the extracts was carried out as well. All of the extracts showed antimicrobial activity on bacteria and yeasts used. Extracts had generally lower MIC values on yeasts. Therefore, yeasts were detected as more susceptible against the propolis extracts than the bacteria. Cytotoxic activity of extract were determined aganist A549 and Beas2B cell lines and IC50 values were calculated. Ma-Arapgir had the highest cytotoxic activity on A549 and Beas2B. They were determined as 6.72 and 26.44 mg/mL, respectively. It could be concluded that propolis extracts have antimicrobial and cytotoxic activity thus, propolis could be used in the treatment of cancer.
The Evaluation of the Levels of Salivary Cortisol and Dental Anxiety in the Case of Some Patients with Bruxism
Authors: Sin Elena-Claudia , Pavel Liliana Lacramioara , Constantin Iulian , Tiutiuca Carmen , Caraiane Aureliana , Albu Maria-Claudia , Murineanu Rodica-Maria , Raftu Gheorghe
Published: May 2020

Dental anxiety as well as fear provokes physical, cognitive, emotional and behavioural responses in an individual. Because there is a lack of information in the specialised literature regarding dental anxiety and bruxism, the present study�s goal was to evaluate the degree of dental anxiety at the level of dental concerns in the case of patients with bruxism in the context of the main dental procedures. It was also aimed for highlighting the efficiency of �tell-show-do� techniques and behavioural control in dental anxiety management in patients with bruxism. The correct evaluation of the patient and identifying the source and level of anxiety will allow the dentist to choose an adequate approach towards the patients, so that their visit to the dentist may have a positive outlook. Because of the fact that in the specialized literature was suggested that nocturnal bruxism is correlated with higher psychological perceived stress levels and salivary cortisol, the aim of this study was to highlight if there are any connexions between the utilisation of occlusal splints for muscle relaxation and behavioural control techniques in the context of lowering the levels of salivary cortisol.
Electrochemical Platform Based on Modified Ti Electrodesto Test a Food Allergen pPresence
Authors: Dumitriu Cristina , Constantinescu Alexandra , Pirvu Cristian
Published: May 2020

Celiac disease (CD) is an autoimmune disorder. For these patients, the only treatment is a gluten free diet. In this work we showed that there can be an easy and cheap method to test gluten presence. We used several modified Ti electrodes. All modified electrodes were prepared using electrochemical methods. Modified electrodes were tested using differential pulse voltammetry in solutions with or without gluten. Selected modified Ti electrode was tested using different known gluten concentrations and extracts from different aliments.
Chemical Treatment with Fluoroquinolones on the Tear Film and Ocular Surface after Cataract Surgery
Authors: Ghita Aurelian Mihai , Ghita Ana Cristina , Istrate Sanziana , Balta Florin , Ciuluvica Radu
Published: May 2020

Quinolone antibacterial activity is related to its chemical structure, a synthetic fluorinated analog of nalidixic acid. Cataract surgery is responsible for visual improvement having a major positive impact on the quality of patients� lives. According to the international guidelines, the administration of levofloxacin after cataract surgery decreases the incidence of postoperatively endophthalmitis. In this context we aimed to study the impact of adding topical fluoroquinolones to the conventional treatment after cataract surgery on the ocular surface and tear film. 125 of eyes of 125 patients with cataract were included. The enrolled patients were divided into three groups, a control group of patients that received topical Tobramycin, Dexamethasone and Indomethacin, a second group where moxifloxacin was added and a third group with levofloxacin instead of moxifloxacin. For all the patients, tear film breakup time, Schirmer II test, slit lamp examination preoperatively and postoperatively at one week were performed together with individual Ocular Surface Disease Index at one week after cataract surgery. The test results revealed that 52% of our studied patients had an abnormal preoperatively tear film breakup time, and 76.8% after cataract surgery, with a statistically significant decrease of the measured values. The preoperatively measured quantity of tears presented a no statistically significant decrease one week after cataract surgery. Also, we found an increase in the percentage of patients with punctate epithelial erosions. It is important and useful to identify prior to surgery patients with ocular surface disease and the ones at risk to develop clinical manifestations in order to treat them accordingly because, cataract surgery exacerbates the preexistent ocular symptoms. The addition of topical fluoroquinolones after cataract surgery in patients with dry eye is safe, with minimal alterations of the ocular surface and tear production, without statistically significant differences as compared to the control group.
Characterizing anhedonia: A systematic review of neuroimaging across the subtypes of reward processing deficits in depression
Authors: Borsini Alessandra , Wallis Amelia St John , Zunszain Patricia , Pariante Carmine Maria , Kempton Matthew J.
Published: May 2020

Anhedonia is a key symptom of major depressive disorder (MDD) and comprises behavioural deficits in three reward processing subtypes: reward liking, reward wanting, and reward learning. However, neuroimaging findings regarding the neural abnormalities underpinning these deficits are complex. We have conducted a systematic review to update, reframe and summarize neuroimaging findings across the three subtypes of anhedonia in MDD. Using PubMed, The Cochrane Library, PsycINFO, and Web of Science databases, we identified 59 fMRI studies comparing participants with current or remitted MDD with controls, using reward processing tasks. For reward liking and wanting, striatal hypoactivation was observed, alongside hypoactivation and hyperactivation across frontal regions. For reward learning, blunted frontostriatal sensitivity to positive feedback was observed. These findings highlight the importance of studying anhedonia not only as a clinical manifestation but also as a neurobiological mechanism underlying depressive disorder and other broader psychiatric conditions.
Photocatalysis with organic dyes: facile access to reactive intermediates for synthesis
Authors: Amos Stephanie G E , Garreau Marion , Buzzetti Luca , Waser Jerome
Published: May 2020

Organic dyes have emerged as a reliable class of photoredox catalysts. Their great structural variety combined with the easy fine-tuning of their electronic properties has unlocked new possibilities for the generation of reactive intermediates. In this review, we provide an overview of the available approaches to access reactive intermediates that employ organophotocatalysis. Our contribution is not a comprehensive description of the work in the area but rather focuses on key concepts, accompanied by a few selected illustrative examples. The review is organized along the type of reactive intermediates formed in the reaction, including C(sp3) and C(sp2) carbon-, nitrogen-, oxygen-, and sulfur-centered radicals, open-shell charged species, and sensitized organic compounds.
Pengaruh Pendekatan Somatis Auditori Visual Intelektual (SAVI) terhadap Peningkatan Kemampuan Koneksi Matematis Siswa SMA
Authors: Septian Ari , Ramadhanty Citra Laila , Rachmawati Puji
Published: May 2020

The purpose of this study are to find out whether increasing students 'mathematical connection ability with learning using the SAVI approach is better with conventional learning, to find out how students' mathematical connection skills with learning the SAVI approach, and to find out a positive relationship between students 'attitudes towards learning using the SAVI approach with increasing students' mathematical connection abilities. This research method is a quasi experiment that tests the use of SAVI approach to the experimental class and conventional learning in the control class. Sampling using purposive sampling. The selected sample is X MIA 1 as the experimental class and X MIA 4 as the control class. The instrument used was a test instrument for mathematical connection ability and a non-attitude scale questionnaire test. The material in this study was Trigonometry. The results of this study are: (1) improvement of students' mathematical connection ability with the SAVI approach is better than with conventional learning, (2) students' mathematical connection skills with learning with the SAVI approach are good, (3) there is no positive relationship between students 'attitudes towards learning with the SAVI approach with increasing students' mathematical connection abilities.
Pencapaian Kompetensi Geometri Siswa dengan Pembelajaran Kooperatif Tipe Pair Checks dan Teams Games Tournament
Authors: R Restiani , Wulandari Ayu , S Suyanto
Published: May 2020

Students also have not been able to formulate interactions between given elements, questions to be solved, and appropriate mathematical concepts to solve the problem. As a result, the achievement of students' geometry competencies is in the gap towards the goals. Therefore, this study aims to determine the differences in the achievement of geometry competence of students on plane geometry subject between cooperative learning type Teams Games Tournament (TGT) and pair checks. This research was conducted on a sample of 72 people, that is 36 students with TGT type cooperative learning and 36 students with pair checks type learning. Samples were selected by cluster random sampling. This research is a quasi-experimental with posttest only nonequivalent control group design. Quantitative data were obtained using test instruments. Research data were analyzed by parametric statistics. Based on data analysis, it was concluded that there were differences in achievement of students' geometry competencies between TGT type cooperative learning and pair checks on plane geometry subject. Model pair checks is an alternative to learning geometry.
Kemampuan Pemahaman Matematis Siswa dengan Menggunakan Cabri 3D
Authors: Tama Bayu Jaya , Rezeki Sri , Hikmah Rezkiyana
Published: May 2020

The purpose of this study was to determine differences in students' mathematical understanding abilities between those using Cabri 3D by using ordinary learning models. This research is a quasi-experimental research. The sample of the research was grade VIII students of one junior high school in Cibinong. The research instrument used was pretest and posttest. Research data were analyzed using t-test. The results of this study indicate that the mathematical understanding ability of students who learn with 3D cabri media is better than students who study with ordinary learning.
ПРАВОВЕ ВИХОВАННЯ УЧНІВСЬКОЇ МОЛОДІ В ЗАКЛАДАХ ПРОФЕСІЙНО-ТЕХНІЧНОЇ ОСВІТИ УКРАЇНИ (70-ТІ РР. ХХ СТ.)
Authors: Пислар А. Б.
Published: May 2020

У статті на основі аналізу джерельної бази досліджено, як було організовано правове виховання учнівської молоді в 70-ті роки ХХ сторіччя в закладах професійно-технічної освіти України.

Розглянуто різні форми правового виховання, використання яких спрямовували на вирішення педагогічними колективами закладів професійно-технічної освіти таких завдань правового виховання: формування правової свідомості; вироблення у вихованців умінь, навичок, звичок поведінки відповідно до правових норм; формування в них активної позиції у правовій сфері; подолання у правовій свідомості вихованців помилкових поглядів і переконань.

Акцентовано, що в 70-ті роки ХХ сторіччя в закладах професійно-технічної освіти України з метою правового виховання молоді проводилися уроки з дисциплін «Питання радянського права» і «Трудове право», а також створювалися університети правових знань, клуби вихідного дня, кабінети і кутки радянського права, у позаурочний час на відповідну тематику організовувалися лекції, лекторії, усні журнали, вечори запитань і відповідей, диспути, бесіди, місячники права, конференції, обговорювалися статті журналу «Людина і закон», виготовлялися стінгазети, діяли загони «Юних дзержинців», суди честі, товариські суди, ради профілактики, перевиховання, здійснювалася просвітницька робота з батьками. Однак перевага надавалася просвітницькій роботі, у процесі якої, як правило, уся увага зосереджувалася на поясненні, переконанні, тобто на формуванні в учнівської молоді правової свідомості, тоді як інші завдання правового виховання часом залишалися поза належною увагою. 

Підсумовано, що, попри вищезгадане, у 70-ті роки ХХ сторіччя в закладах професійно-технічної освіти України до організації правового виховання учнівської молоді підходили комплексно, а роботу з цього напряму виховання проводили цілеспрямовано та систематично.
ЕТАПИ СТАНОВЛЕННЯ ТА РОЗВИТКУ МОРСЬКОЇ ОСВІТИ УКРАЇНИ В ДРУГІЙ ПОЛОВИНІ ХХ – ПОЧАТКУ ХХІ СТОЛІТТЯ
Authors: Жорова І. Я.
Published: May 2020

У статті висвітлено основні етапи становлення та розвитку морської освіти України в другій половині ХХ століття – на початку ХХІ століття. Ґрунтовний аналіз публікацій та досліджень вітчизняних та зарубіжних науковців, нормативних документів, наказів та постанов СРСР показав, що становлення та розвиток морської освіти в окреслений період поділяється на три етапи. Охарактеризовано перший етап (40-ві роки - 60-ті роки ХХ століття), який пов’язаний із відновленням роботи морських навчальних закладів, перебудови морського флоту. З’ясовано, що другий етап (кінець 60-тих – 1990 р.) пов’язаний із вдосконаленням та реорганізацією професійно-технічних навчальних закладів. Аналіз архівних документів показав, що головними завданнями морського навчального закладу є підготовка кваліфікованих морських фахівців, які мають необхідні теоретичні знання і практичні навички за фахом, вихованих у дусі марксизму-ленінізму, радянського патріотизму, дружби народів і пролетарського інтернаціоналізму. З’ясовано, що на третьому етапі (1991 р. – початок ХХІ ст.) чітко простежується ідентичність процесів, що відбуваються в системах морської освіти та вищої професійної освіти. Аналіз літератури показав, що відповідно до тенденцій розвитку морської освіти в країні з кінця 90-х років почалася перебудова навчально-виховного процесу, яка здійснювалась за такими напрямами: зміна навчальних планів з метою розширення загальнотеоретичної і методичної підготовки курсантів; удосконалення системи управління навчально-виховним процесом, для чого були розроблені критерії оцінки якості й ефективності роботи кафедр і факультетів; оптимізація графіків навчального процесу з метою скорочення аудиторних занять до 24-28 годин на тиждень; розробка положення про атестацію студентів у міжсесійний період; запровадження договірних умов підготовки фахівців; розробка кваліфікаційних характеристик другого покоління; активізація впровадження методів інформаційних технологій у навчальний процес.