bluuebunny/crossref_metadata_2025 huggingface dataset:
Оценка конкурентоспособности предприятий как элемент маркетинговой стратегии
Authors: Кузьменко О.В. , Мостипан С.В. , Жукова Е.В.
Published: May 2023

В статье представлены теоретические подходы к определению маркетинговой стратегии предприятия, приведены этапы формирования стратегии маркетинга, среди которых особое внимание уделено стратегическому анализу маркетинговой среды. Одним из инструментов стратегического анализа среды функционирования предприятий являются методы оценки конкурентоспособности хозяйствующих субъектов. В работе раскрыта сущность основных методов оценки конкурентоспособности. В качестве примера приведена оценка конкурентоспособности ведущих сельскохозяйственных организаций Белоглинского района Краснодарского края, по результатам которой построена конкурентная карта зернового рынка. Результаты оценки уровня конкурентоспособности предприятий Белоглинского района позволили сформировать их рейтинг и определить предприятие, нуждающееся, в первую очередь, в разработке маркетинговой стратегии с целью приобретения конкурентных преимуществ и укрепления своей позиции на конкурентном зерновом рынке района.
Управление кадровой безопасностью организации (правовой аспект)
Authors: Удалов Д.Э.
Published: May 2023

В статье рассматриваются основополагающие принципы кадровой безопасности организации. Анализируются правовые аспекты обеспечения кадровой безопасности в организации. Состояние безопасности организации необходимый фактор ее функционирования и развития. Соответственно вопросы безопасности непосредственно связаны с процессом управления персоналом организации.
Нарушения углеводного обмена у больных с новой коронавирусной инфекцией
Authors: Фазлова И.Х. , Тарасова Е.А. , Уланова А.А. , Радайкина Е.В. , Радайкина О.Г. , Гуранова Н.Н.
Published: May 2023

Проведен анализ частоты развития и характера нарушений углеводного обмена у больных с новой коронавирусной инфекций путем ретроспективного изучения амбулаторных карт пациентов, перенесших COVID-19 в 2021 году. Проанализировано 168 амбулаторных карт, отобранных случайным способом. Установлено, что среди пациентов со значительным и субтотальным поражением легочной ткани сахарный диабет встречался более чем в 2 раза чаще. У пациентов, ранее не страдавших сахарным диабетом, гипергликемия на фоне коронавирусной инфекции развивалась в половине изученных случаев и не зависела от объема легочной инфильтрации. В 1/3 случаев гипергликемия сохранялась после выписки из стационара и в последующем этим пациентам впервые был диагностирован сахарный диабет.
FACTORS AFFECTING ADEQUATE MYOCARDIAL PERFUSION IN PATIENTS WITH ACUTE ST-ELEVATION MYOCARDIAL INFARCTION WITH SUCCESSFUL EPICARDIAL FLOW
Authors: AYDINYILMAZ Faruk , ÖZBEYAZ Nail Burak , ALGUL Engin , GULIYEV İlkin , ŞAHAN Haluk Furkan , ÖZKAYA İBİŞ Ayşenur , KALKAN Kamuran , SUNMAN Hamza
Published: May 2023

Aim: The aim of this study was to evaluate and compare multifarious parameters between complete and incomplete ST-segment resolution (STR) patients groups and to identify associates of STR in patients with acute ST-segment elevation myocardial infarction (STEMI) after successful primary percutaneous coronary intervention (pPCI).

Material and Methods: 888 consecutive patients were divided into two groups according to the STR
Acil Servise Başvuran COVID-19 Hastalarında Mukosiliyer Klirensin İncelenmesi
Authors: UZUNGET Sinan Cem , ERTÜRK Zamir Kemal , BAYRAK Sevinç , ÜNAL Hidayet Can , TÜRKKANI Mustafa Hamidullah
Published: May 2023

Öz

Solunum yolu epitelinde yer alan mukosiliyer tabaka, solunum yollarındaki ilk koruma mekanizması olarak görev yapmaktadır. Şiddetli akut solunum sendromu koronavirus-2 de (SARS-Cov-2), diğer bazı solunum yolu virüsleri gibi siliyer hücrelere yapışmakta ve mukosilier aktiviteyi etkilemektedir. Sakkarin testi ile mukosilier klirensin ölçülmesi mümkündür. Çalışmamızda acil servise başvuran hastalarda SARS-CoV 2 ye bağlı olarak gelişen Korona virus hastalığı-2019 (COVİD-19) enfeksiyonunda erken dönemde mukosiliyer klirensin etkisini değerlendirmeyi amaçladık

Gereç ve Yöntem:

Acil servise başvuran ve son 48 saat içerisinde COVID-19 düşündüren yakınmaları olan ve Polimeraz zincir reaksiyonu (PCR) testi çalışılan 84 kişilik hasta grubunda mukosilier klirens zamanı (MCT), sakkarin testi ile ölçülerek sağlıklı gönüllülerde yapılan ölçüm ile karşılaştırılmıştır.

Sonuçlar

PCR pozitif olarak tespit edilen katılmcılarda ortalama MCT 14.58 dakika olarak, sağlıklı gönüllülerde ise ortalama MCT 13.72 dakika olarak ölçüldü. İki grup arasında istatistiksel açıdan fark saptanmadı (p=0,657).

Tartışma

COVID-19 etkeni olan SARS-CoV-2’nin solunum yolu epiteli hasarı yaptığı ve solunum yollarında hastalık oluşturduğu bilinmektedir. Erken dönemde yapılan PCR testlerinde üst solunum yolu mukozasında tespit edilmekle beraber, erken dönemde MCT üzerine etkisi bulunmamaktadır.
Pod and Seed Production Potential of Vegetable Pea (Pisum sativum L.) as Influenced by Different Levels of Sulphur and Boron in Calcareous Soil of North Bihar
Authors: Kumar Udit , Bihari Chhail , . Pramila , Prasad K. , Sinha B.M. , Ghosh Saipayan , Patel Vivek Kumar , . Dharminder , Kishor Kaushal
Published: May 2023

Background: Vegetable pea is one of the relevant vegetable crops grown in the cool season all over the India. Sulphur deficiency is becoming more prevalent in Bihar due to the less use of boron and sulphur-containing fertilizer in calcareous soils and the consequent decrease in sulphur and boron nutrients. On the other hand, organic matter-rich manures, are utilized in very small quantities which is a source of a macro-and micronutrients, including sulphur and boron. As a consequence, soils have become deficient in sulphur and boron, which is detrimental to crop production. In the absence of these sulphur and boron in the soil, different legume crops such as vegetable pea suffer from reduced growth, yield and nodule formation. Methods: In this field investigation during 2020-2022, experiments were conducted in Factorial Randomized Block Design using fifteen different combinations of Boron and Sulphur doses in Azad Pea-3 variety of vegetable pea in three replications and different pod and seed yield attributing traits were studied. Result: Among the different treatments, it has been inferred that treatment combination 40 kg S ha-1 + 2 kg B ha-1 exhibited superiority over rest of the treatment combinations with respect to pod and seed yield attributes of vegetable pea.
Peran Politik Tokoh Agama pada Pemilu
Authors: Amin Muhammad , Izomiddin Izomiddin , Anisya Siti
Published: May 2023

ABSTRAK

Kajian tentang tokoh agama dan juga perananya dalam politik selalu menarik untuk dibahas.Karena tokoh agama sendiri memiliki kharismatik dan juga pengetahuan agama yang sangat melekat pada dirinya, sehingga masyarakat selalu mendiskusikan permasalahan keagamaan dan juga permasalahan lainnya termasuk politik. Dan juga menggunakan atau memanfaatkan figur Tokoh Agama untuk memenangi dalam pemilu adalah sah-sah saja, asal tokoh agama itu sendiri bisa memposisikan diri sebagai pengarah ke arah yang lebih positif dan lebih baik. Juga yang lebih penting peran tokoh agama atau kyai dalam percaturan kancah politik tidak melupakan tujuan mulia yaitu mengajak masyarakat untuk sadar menggunakan hak pilihnya yang tentunya untuk memilih pemimpin yang amanah. Adapun tujuan dari penelitian ini adalah untuk mengetahui peran tokoh agama Pada Pemilu tahun 2019. Adapun metode yang digunakan dalam penelitian ini adalah penelitian kualitatif. Peran yang dilakukan oleh tokoh agama dalam pemenangan pemilu tentunya tidak terlepas dari otoritas kharismatik yang dimiliki serta melalui perangkat peran dan fasilitas peran. Terdapat 3 peran yang dilakukan oleh para tokoh agama dalam perananya Pertama, berperan sebagai pembentuk opini di dalam masyarakat. Kedua, berperan sebagai penggerak massa, dan ketiga, berperan sebagai orang yang berkampanye.

Kata kunci: tokoh agama, pemilu, politik.
Trade Tax Through The Electronic System (PMSE) In The Sharia Maqasid Perspective According To Jasser Auda
Authors: Nabilah Deva
Published: May 2023

This study aims to analyze Trade Tax Through Electronic Systems based on the perspective of Maqashid Syariah according to Jasser Auda. This research is a library research (library research) through a statutory approach (statute approach) which takes an approach through the perspective of Jasser Auda's maqasid syariah on tax purposes that emphasize the benefit of the people to create social values such as helping fellow people. The type of research data is normative juridical using data collection methods in the form of literature studies by collecting documents and data to be processed using analytical methods. In this study, there are 6 system features, namely cognitive nature, interrelatedness, wholeness, openness, multi-dimensionality and meaningfulness so that it gives rise to the perspective that the principle of tax collection must contain the principles of justice and the benefit of the people in order to bring prosperity and economic prosperity to all people with the principle of openness but on the basis of openness to the world and philosophy. In accordance with the aim of maqasid asy-shari'ah that all forms of effort are to bring goodness and avoid harm (harm).
PENERAPAN PRINSIP-PRINSIP EVALUASI PEMBELAJARAN PADA MATA PELAJARAN AL-QUR’AN-HADITS
Authors: S Muhammad Arjuna , Ismail Fajri , Lutfiah Husnah
Published: May 2023

The purpose of this research is to find out how the application of the principles of learning evaluation is carried out in MA Aulia Cendikia. Knowing how the application of the principles of learning evaluation is carried out, it is expected to serve as an evaluation material to improve the quality of education. This research uses descriptive research method, with qualitative approach through observation, interview and documentation using Datan Miles and Huberman analysis techniques. The results of this research are the principles of learning assessment has been conducted, including the principle of integration, pedagogical principles, accountability principles, contingency principles, cooperative principles and there is a principle that is not able to apply in learning assessment activities such as the principle of objectivity.Factors that influence the application of learning evaluation principles to improve student learning outcomes in Al-Qur'an Hadith MA Aulia Cendikia Palembang subject are school administration policies that require teachers to create learning evaluation plans, motivation, teacher's ability to master the material, limited learning hours, teacher accountability and learning infrastructure that really needs to be considered to support this smooth process.
Upaya Meningkatkan Kualitas Pendidikan melalui Peran Kepala Sekolah
Authors: Mahdali Fitriyah , Abdulloh Abdulloh
Published: May 2023

The focus of this research is emphasized on the quality of education at SMK Muhammadiyah 7 Gondanglegi, which is about the principal's efforts to improve the quality of education.There are several arguments that form the basis of this research, first, this school is included one of the leading Vocational High Schools (SMK) in Malang Regency. Second, although this school is relatively new compared to other schools in Gondanglegis sub-district is able to provide quality, quantity, even facilities exceed other schools in Gondanglegi.And third, this school has issuing high quality graduates (outputs) where these graduates are now widely scattered in several colleges. There is a limitation of the problem in this study so that the problem formulation is concluded which was taken by researchers to conduct this research, namely (1) How is the effort of the head schools in improving the quality of education at Muhammadiyah 07 Gondanglegi Vocational High School (SMK) Malang (2) How is the success of the principal in improve the quality of education in Muhammadiyah Vocational High School (SMK) 07 Gondanglegi Malang (3) How is the success of the principal in improving the quality of education in Muhammadiyah 07 Vocational School (SMK) Gondanglegi Malang. The method used in this research is descriptive qualitative, namely one a type of research that aims to describe and understand certain phenomena.Method data collection used is by means of documentation and interviews.The findings of this study are (1) the principal's efforts to improve the quality of education which is done in many ways.(2) obstacles faced by school principals as well solutions / policies in improving the quality of education (3) The success of the principal in improving the quality of education, in this case the researcher reveals the success this by describing the achievements and reputations that were obtained and held by the SMK Muhammadiyah 07 Gondanglegi during the last four years in the leadership of Bpk H. Pahri, S.Ag., MM.

 

Keywords: Education; quality; principal
Analisis Manajemen Program Mujahadah dan Pembibitan Tahfizhul Qur’an
Authors: Susanto Doni
Published: May 2023

This study aims not only to assist students in achieving or improving the quality of memorizing the Al-Qur'an, which they mastered while studying at the Aliyah madrasah, but also to prepare alumni who will be able to continue their studies abroad, knowledgeable but adhering to the "aqeedah ahlussunnah wal jama'ah." This study used the descriptive-qualitative method. The data collection technique uses interview, observation, and documentation techniques. After the data is collected, data reduction, data presentation, and conclusions are drawn. Checking the validity of the data using triangulation and reference materials The Al-Ittifaqiah Indralaya Mujahadah and Nursery Program (MABIT) is a preparatory program for studies in the Middle East and Europe with various models or program classes. So that the Management of the MABIT Al-Ittifaqiah Indralaya Program is a forum or institution for managing educational programs in Al-Ittifaqiah Indralaya and is based on professional management, starting from program planning, program organization, program implementation, and program supervision.
Projeto histórico e expografia em Design no Brasil: História e Realidade
Authors:   Universidade Estadual de Campinas, Ribeiro Ana Luisa
Published: May 2023

O desenvolvimento das experiências de Lina Bo Bardi no campo museográfico perpassa grande parte de sua experiência no Brasil, por vezes entremeado e sobreposto à atuação multidisciplinar de Lina nos campos da arquitetura, cenografia e atividade editorial. Desde sua chegada ao Brasil até meados da década de 80, Lina seria responsável pela museografia do Museu de Arte de São Paulo (MASP) à rua Sete de Abril, à partir de 1947; realizaria a exposição Bahia no Ibirapuera (1959); as exposições Nós e o Passado, Formas Naturais e uma série de exposições didáticas no Museu de Arte Moderna da Bahia (MAMB) à partir de 1960; organizaria a exposição Nordeste, no recém fundado Museu de Arte Popular da Bahia (MAP); inauguraria o MASP Trianon com A Mão do Povo Brasileiro (1969); ainda no MASP montaria a exposição Repassos (1975); e por fim realizaria as exposições Design no Brasil: História e Realidade, Mil Brinquedos para a Criança Brasileira, Caipiras, Capiaus: Pau-a-pique e Entreatos para Crianças em seqüência ininterrupta (1982-1985) no SESC Pompéia.
A “era” Zanini: uma reavaliação da história do MAC USP nos anos de 1963 a 1978
Authors:   Universidade de São Paulo, Hoffmann Ana Maria Pimenta
Published: May 2023

A produção artística contemporânea caracteriza-se pela multiplicidade. Dar conta da abertura proposta pelas suas inúmeras produções significa em grande parte, analisar a crítica institucional que muitas obras postulam. Neste artigo gostaria de apresentar meu acompanhamento destas mudanças na história de alguns museus brasileiros, entre os anos de 1950 e 1970.
Amilcar de Castro: pintor?
Authors:   Universidade Estadual de Campinas, Mol Elias Perigolo
Published: May 2023

Amilcar de Castro não se considerava pintor e, por consequência, não se via como produtor de pinturas, preferindo denominar toda sua produção com uso de tinta, a partir de 72, quando retorna dos Estados Unidos, de desenhos. Em várias entrevistas, há uma separação entre desenhista, aquele que enxerga o mundo por meio de linhas, e pintor, o que vê o mundo através de cores.
Caricatura e sátira na desterro do século XIX: o periódico crítico Matraca
Authors:   Universidade do Estado de Santa Catarina, Didoné Fabiana Machado
Published: May 2023

A caricatura é uma representação gráfica ou plástica de uma pessoa, idéia ou acontecimento interpretada propositalmente de forma distorcida e exagerada, acentuando ou revelando aspectos específicos. Já a sátira, desenvolvida primeiramente na forma literária, se utiliza da caricatura para fazer julgamentos morais. A sátira social está concentrada em pessoas comuns e situações cotidianas, já a sátira política, ridiculariza figuras públicas e reage a eventos e polêmicas políticas da época em questão. Impiedosos ou amenos, cruéis ou generosos, os caricaturistas, com poucas linhas em uma folha em branco, são capazes de retratar toda uma época.
Arte e história: o museu Afro Brasil e o papel da curadoria na construção da narrativa museal
Authors:   Pontifícia Universidade Católica de Campinas, Matos Isla Andrade Pereira de
Published: May 2023

O Museu Afro Brasil foi criado no ano de 2004 através da iniciativa do artista baiano Emanoel Araújo, sob a proposta de desconstruir o imaginário da população negra, associado à escravidão, reforçar a autoestima dessa população excluída ao longo da história nacional, transformar para a igualdade e o sentimento de pertencimento e estabelecer a inclusão social deste grupo e o respeito à cultura de matriz africana.
Porta adentro: cenas de intimidade na pintura de Belmiro de Almeida
Authors:   Universidade Federal de Juiz de Fora, Vieira Samuel Mendes
Published: May 2023

A produção artística e o ensino das artes no Brasil dos oitocentos tem sido alvo de importantes reavaliações críticas, que desde as décadas de 1970, passando pelos anos 1980 até a atualidade, trouxeram avanços e revisões com o intuito de ampliar a compreensão e eliminar conceitos generalizantes e restritivos. Essa literatura renovada, resultado de novas abordagens e diferentes pontos de vista, contribuiu na valorização de obras e artistas antes negligenciados pela crítica modernista.
Em hipocampo: alegoria e a crítica da fotografia no espaço expositivo
Authors:   Universidade Estadual de Campinas, Mendes Talita
Published: May 2023

Na instalação Hipocampo, realizada por Rosângela Rennó em (1995), percebese a alternância de dois espaços configurados pela artista: o retorno cíclico e programado do espaço expositivo e o da câmara escura. A aparição desta última é acionada pelo jogo parafrástico do acender e apagar a luz, provocando uma associação metafórica que pode ser sintetizada na expressão “a câmara escura é o cubo branco”.
A phenomenological study on the difficulties and meanings experienced by beginner counselors in youth institutions
Authors:   The Association of Korea Counseling Psychology Education Welfare, KANG Seo-Yeon , KEUM Changmin
Published: May 2023

This study attempted to explore the difficulties experienced by first-time counselors in youthinstitutions and their meanings. The study participants selected six counselors with less thanthree years of experience and conducted in-depth interviews, and analyzed them usingGiorgi(1985)'s phenomenological research method. As a result of the study, the difficultiesexperienced by first-time counselors are 'experience various situations that are difficult to applycounseling theory', 'facing obstacles in the unexpected field', 'limitations due to lack of expertiseof counselors', 'ethics vs. There were psychological conflicts caused by reality, difficulties causedby negative views on counseling, and difficulties caused by clients. In addition, it was confirmedthat the participants “discovered a way to overcome the limitations of the field” and “felt theneed for development as a counselor” and found meaning in the field. In this study, through thedifficulties experienced by youth counselors in youth institutions and the meaning of the process,discussions on the development of counselors and on-site efforts were proposed.
An Exploration of Impostor Syndrome in STEM and STEM Self-Efficacy in Adolescent Learners from a Teacher’s Perspective
Authors: Amoa-Danquah Portia
Published: May 2023

Over the years, there has been a surge in the demand for a proficient STEM (Science, Technology, Engineering, and Math) workforce to occupy the proliferating STEM job vacancies worldwide. The STEM workforce must be expanded in order to fill this gap. However, the reputation of STEM learning as being arduous has proven to be a deterrent to students’ interest in the pursuit of STEM careers. In an expounding qualitative study, three STEM teachers were interviewed for the purpose of examining STEM Impostor Syndrome (IS) and STEM Self-Efficacy (S-SE) from a teacher’s perspective. Findings suggest that teachers are sentient of the manifestation of STEM IS among students. Teachers noted that STEM IS poses a significant challenge for their interactions with students in the classroom, and also suggested that STEM IS is inversely proportional to S-SE.
Estimating wolf abundance with unverified methods
Authors: Treves Adrian , Santiago-Ávila Francisco J.
Published: May 2023

Wildlife abundance can be very difficult to estimate, especially for rare and elusive species, such as wolves. Over nearly a century, wolf scientists have developed methods for estimating abundance across large areas, which involve marked animals being detected again after capture, sometimes supplemented by observations of the associates of those marked animals. Recently, several US jurisdictions have departed from those proven methods to explore alternatives that are believed to be less expensive for wolf populations estimated >1000 individuals. The new methods sacrifice precision but are believed to retain adequate accuracy and sensitivity to changing conditions for reliable decision-making. We review evidence for the accuracy, precision, sensitivity, and reproducibility of the new “scaled occupancy model” (SOM) applied in Wisconsin. We conclude that the Wisconsin method would systematically overestimate wolf abundance by large (but currently incalculable) margins. Because Wisconsin, similar to other states, not only changed to unverified methods but also implemented widespread wolf-killing, shortcomings in their estimates of wolf abundance may have far-reaching consequences for population viability and confidence in state wildlife policy. We discuss findings from Wisconsin alongside similar findings for other states’ occupancy models being insensitive to human causes of mortality that have recently increased. Overall, Wisconsin’s method for estimating wolf abundance shows significant departures from best practices in scientific measurement. Verification will require independent replication and unbiased tests at multiple scales in multiple habitats under different human-induced mortality rates and rigorous independent review before the new methods are considered reliable.
Reference Values for the Grocery Shelving Test among United Arab Emirates Population: A Cross Sectional Study
Authors: Alaparthi Gopala Krishna , Gatty Aishwarya Prabhakar , Isa Huda , Hassan Latifa , Khalid Noura , Osman Abdullah , Mahmoud Sara , Tamim May , Bairapareddy Kalyana Chakravarthy , De Sa Ferreira Arthur
Published: May 2023

Background: Arm elevation plays an important role in simple and complex daily tasks. Muscles that stabilize the shoulder girdle also function as respiratory accessory muscles. Dual demand on these muscles, particularly in patients with chronic respiratory conditions, leads to dyspnea and fatigue of the upper limb, making simple daily activities difficult. Various tests, including Grocery Shelving Task (GST), are designed to assess functional performance during upper limb activities. The aim of the study is to derive reference values for GST among the population of the United Arab Emirates
Methods: This cross-sectional study was conducted with 220 healthy individuals of both genders between the ages of 20 and 69. Duration required to complete GST was recorded. The correlation between duration and age, height, body mass and body mass index (BMI) were also assessed.
Results: Reference values for duration (in seconds) in females for age groups 20-29, 30-39, 40-49, 50-59 and 60-69 are 43.5±5.5, 43.1±8.08, 48.1±6.7, 44.9±7.1, 46.7±6.5 respectively. Values for males of age groups 20-29, 30-39, 40-49, 50-59 and 60-69 are 45.7±6.7, 44.8±8.9, 42.5±10.01, 53.4±4.2, and 53.9±5.4 respectively.
Conclusion: Reference values for GST duration were obtained. Weak correlations were found between duration and age, height, body mass, BMI of the participants.
Challenges for District Heating in Poland
Authors: Talarek Karolina , Knitter-Piątkowska Anna , Garbowski Tomasz
Published: May 2023

Currently, the district heating (DH) in Poland is facing many challenges. The business model used hitherto was very simple—in most cities, heating plants produced heat, and centralized heating systems supplied the "product" at a price approved annually by the president of the Energy Regulatory Office (URE). However, recent years have brought significant changes on the market. EU regulations force the elimination of old coal-fired plants that were still built in the Polish People's Republic (PRL), moreover, high prices of CO2 emission allowances aggravate the financial situation of companies. In addition, in the heating sector, the trend observed in the power sector is becoming increasingly visible—limiting the role of large sources in favor of energy generated locally, closer to the customer. One of the biggest challenges is achieving the targets set by the EU for the share of renewable energy sources (RES) in the heating sector. The war in Ukraine and problems with the supply of coal and gas are an additional impulse to turn to RES. Thus, the development of sustainable and innovative solutions for energy production and supply at the level of urban networks is currently one of the main technical challenges. The purpose of the paper is to present the current situation and perspectives of development of district heating systems in Poland with a view to the status of district heating in the world, and some deeper insight into European conditions. The review presents energy sources with particular emphasis on renewable energy sources (RES) and their cogeneration for heat production. The examples of existing heating network solutions using renewable energy sources, based on the selected published case studies, are also discussed.
Association of Positive Hepatitis B Serology Markers With Risk and Behavior Factors in Kazakhstan Blood Donors: A Cross Sectional Study
Authors: Savchuk Tatyana , Grinvald Yelena , Ali Mohamed , Sepetiene Ramune , Saussakova Saniya , Zhagazieva Kuralay , Imashpayev Dulat , Abdrakhmanova Saniya
Published: May 2023

Background and Aim. Recently made analysis for anti-HBcor prevalence within Kazakhstan blood donors population concluded 17.2% rate. Considering these data are among the highest of infectivity results worldwide, an objective of this study was to define an association of positive Hepatitis B serology markers with risk and behavior factors.
Methods. The blood donors’ samples were tested for anti-HBcore total (IgG/IgM) and anti-HBs, by CLIA on the Architect i2000SR platform (Abbott). Surrogate alanine transferase (ALT) markers for all blood donors were tested by kinetic method on the Biosystems A25 analyzer. A questionnaire was developed for socio-demographic characteristics, donors’ nutrition habits, cholesterol levels and history of smoking, alcohol consumption. Informed consent was obtained from all study participants. Statistics was calculated using the R software program (version 4.1.1, USA, 2021).
Results. A group of 5709 blood donors participated in the study. Participants with positive anti-HBcore scores were on average older (41.8 vs 34.4 years, p<0.001), Kazakh (88.7% vs 83.0%, p<0.001), married (74.0% vs 55.6%, p<0.001), had a secondary education (70.1% vs. 59.4%, p=0.03), smoked (27.9% vs. 24.3%, p=0.05), had a longer smoking history (13.6±9.5 years vs. 9.8±8.5 years, p<0.001), and various hypercholestesterolaemia (6.2% vs 3.9%, p=0.02). Predominantly their main meal was dinner (17.0% vs 14.2%, p=0.03).
Analysis for associations of socio-demographics characteristics, risk factors, nutrition with anti-HBs, showed that those who have secondary education level (70.1%) were more likely to be anti-HBs-positive (p=0.03). No other significant correlations for anti-HBs were observed.
Conclusions. The risk factors and behavior analysis highlighted the blood donors’ overall health status. Positive Hepatitis B markers associated with statistically significant characteristics from socio-demography, nutrition habits or risk factors could support further pathogenesis studies looking for HBV treatment guides fulfilling the existing gaps.
Synthetic Data & the Future of Women's Health: A Synergistic Relationship
Authors: Delanerolle Gayathri , Phiri Peter , Cavalini Heitor , Benfield David , Shetty Ashish , Bouchareb Yassine , Shi Jian , Zemkoho Alain
Published: May 2023

Abstract ObjectivesThe aim of this perspective is to report the use of synthetic data as a viable method in women’s health given the current challenges linked to obtaining life-course data within a short period of time and accessing electronic healthcare data. Methods We used a 3-point perspective method to report an overview of data science, common applications, and ethical implications. Results There are several ethical challenges linked to using real-world data, consequently, generating synthetic data provides an alternative method to conduct comprehensive research when used effectively. The use of clinical characteristics to develop synthetic data is a useful method to consider. Aligning this data as closely as possible to the clinical phenotype would enable researchers to provide data that is very similar to that of the real-world. Discussion Population diversity and disease characterisation is important to optimally use data science. There are several artificial intelligence techniques that can be used to develop synthetic data. ConclusionSynthetic data demonstrates promise and versatility when used efficiently aligned to clinical problems. Therefore, exploring this option as a viable method in women’s health, in particular for epidemiology may be useful.
Cervical Necrotizing Fasciitis: a life-threatening emergency in Oral and Maxillofacial Surgery
Authors: De Leyva Patricia , Cárdenas-Serres Cristina , Ranz-Colio Álvaro , Almeida Fernando , Sánchez-Jáuregui Eduardo , Dios-Díez Paula , Acero Julio
Published: May 2023

Necrotizing fasciitis is a life-threatening soft-tissue infection affecting the deep fascia and subcutaneous tissue. It is characterized by a fulminant course and high mortality rates. NF of the head and neck is very rare, most cases being odontogenic in origin. Streptococcus spp. and Staphylococcus spp. are the most common isolated organisms. If the infection progresses to descending mediastinitis the prognosis becomes very poor. Since the initial clinical features can be similar to those of a non-necrotizing deep cervical infection, a high degree of suspicion is critical for an early diagnosis. Computed tomography scan can be useful in the diagnosis and to define the extent of the infection. Early and aggressive surgical debridement of all compromised tissue and antibiotic therapy and fluid resuscitation are essential and should not wait for bacterial culture results. Despite prompt and adequate treatment, mortality of CNF can be as high as 35%.
Active Device for Shoulder Rehabilitation Based on Force Control
Authors: Alguacil-Diego Isabel M. , Cuesta-Gómez Alicia , Pont-Esteban David , Carrillo-Rios Juan , Espinosa-Peralta Paul , Sánchez-Urán Miguel Ángel , Ferré Manuel
Published: May 2023

This paper describes the design and development of an active device that was applied to shoulder rotation rehabilitation. It implements a force control in a similar way to the haptic devices that reflect a force on the user’s hand according to the rehabilitation parameters. This device was tested with patients, combining clinician manipulation and programmed exercises. The results were excellent, given that the range of movement of the shoulder increased in most of the pa-tients. The results of the Usability Scale questionnaire were also promising.
Seasonal Divergence in the Weakening Relationship between Interannual Temperature Changes and Northern Boreal Vegetation Activity
Authors: Zhao Haijiang , Jin Ning , Wang Xiurong , Fu Guiqin , Xiang Kunlun , Zhao Jie
Published: May 2023

The response of boreal vegetation to global warming has shown a weakening trend over the last three decades. However, in previous studies, models of vegetation activity responses to temperature change have often only considered changes in mean daily temperature (Tmean), with the diurnal temperature range (DTR) being neglected. The goal of this study is to evaluate the temporal trends of the relationships between two temperature factors (Tmean and DTR) and vegetation activity across the boreal regions on both annual and seasonal timescales, by simultaneously employing satellite and climate datasets. We found that the interannual partial correlation between growing season (GS) NDVI and Tmean (RNDVI−Tmean) showed a significant decreasing trend over the last 34 years. At the seasonal scale, RNDVI−Tmean shows a significant upward trend in the spring, while in the summer and autumn, RNDVI−Tmean exhibits a significant downward trend. The temporal trend characteristics of the partial correlation between NDVI and DTR (RNDVI−DTR), at both the GS and seasonal scales, are fully consistent with RNDVI−Tmean. The area with a significant decrease in GS RNDVI−Tmean and RNDVI−DTR accounted for approximately 44.40% and 41.21% of the boreal region with the 17-year moving window, respectively. In stark contrast, the area exhibiting a significant increasing trend in GS RNDVI−Tmean and RNDVI−DTR accounted for only approximately 14.65% and 13.59% of the boreal region with the 17-year moving window, respectively. With respect to the seasonal patterns of RNDVI−Tmean and RNDVI−DTR, the area with a significant upward trend in spring was greater than that with a significant downward trend. Nevertheless, more areas had a significant downward trend of RNDVI−Tmean and RNDVI−DTR in summer and autumn than had a significant upward trend. Overall, our research reveals a weakening trend in the impact of temperature on vegetation activity in the boreal regions, and contributes to a deeper understanding of the vegetation response to global warming.
Potential of Personalized Dendritic Cell-Based Immunohybridoma Vaccines to Treat Prostate Cancer
Authors: Hawlina Simon , Zorec Robert , Chowdhury Helena H.
Published: May 2023

Prostate cancer (PCa) is the most commonly diagnosed cancer and the second most common cause of death due to cancer. About 30% of patients with PCa who have been castrated develop a castration-resistant form of the disease (CRPC), which is incurable. In the last decade, new treatments that control the disease have emerged, slowing progression and spread, and prolonging survival while maintaining the quality of life. These include immunotherapies; however, we do not yet know the optimal combination and sequence of these therapies with the standard ones. All therapies are not always suitable for every patient due to co-morbidities or adverse effects of therapies or both, so there is an urgent need for further work on new therapeutic options. Advances in cancer immunotherapy with an immune checkpoint inhibition mechanism (e.g., ipilimumab, an anti-CTLA-4 inhibitor) have not shown a survival benefit in patients with CRPC. Other immunological approaches have also not given clear results, which has indirectly prevented breakthrough for this type of therapeutic strategy into clinical use. Currently, the only approved form of immunotherapy for patients with CRPC is a cell-based medicine, but it is only available to patients in some parts of the world. Based on the experience gained from recently completed clinical research on immunotherapy with dendritic cell-based immunohybridomas, the aHyC dendritic cell vaccine, for patients with CRPC, we highlight the current status, and possible alternatives that should be considered in the future.
The Influence of Nicotine on Trophoblast-Derived Exosomes in a Mouse Model of Pathogenic Preeclampsia
Authors: Kubo Ayane , Matsubara Keiichi , Matsubara Yuko , Nakaoka Hirotomo , Sugiyama Takashi
Published: May 2023

Preeclampsia (PE) is a serious complication of pregnancy with a pathogenesis that is not fully understood, though it involves the impaired invasion of extravillous trophoblasts (EVTs) into the decidual layer during implantation. Recently, others have found that diverse cell types, including EVTs, produce exosomes filled with molecular cargo (mainly proteins and RNAs) that can be transported to other cells and organs both locally and long-range. The cargo delivered by exosomes can signal to and modify the receiving cells and their environment, and EVT-derived exosomes may influence the pathogenesis of PE. Because the risk of PE is actually decreased by cigarette smoking, we considered the possibility that nicotine, a critical component of tobacco smoke, might protect against PE by modifying the content of exosomes from EVTs. In this study, we applied nicotine stimulation to cultured EVTs and subjected their secreted exosomes to proteomic analysis. We identified many proteins whose abundance in exosomes was modified by nicotine treatment of the donor EVTs, and we used bioinformatic annotation and network analysis to select five key hub proteins with potential roles in the pathogenesis or prevention of PE.
The use of APE in the Problem-Based Learning Process in English subjects
Authors: Rais Pandi , Nurdyansyah Nurdyansyah
Published: May 2023

Every effective, inventive, and creative educational procedure will result in high-caliber students. Hence, every instructor should be able to instruct using a good, student-friendly learning model so that when learning is implemented, pupils can do so successfully. Apart from selecting the learning model to be utilized, the teacher must have innovative ideas and methods for creating instructional materials that will be delivered to students, especially in English content, if they are to follow the learning process with ease. One of these involves employing educational media. Students will be able to follow the learning process with excitement and fun if appropriate learning materials are used, which will prevent them from becoming disinterested. With the "APE media Secret Food Chain Box," this problem-based learning can be carried out. Problem-based learning, where problems from a lesson are used to help students build their problem-solving skills and also.
PEMBIAYAAN KREDIT PEMILIKAN RUMAH (KPR) SUBSIDI UNTUK MENINGKATKAN KESEJAHTERAAN MASYARAKAT BERPENGHASILAN RENDAH
Authors: Azis Mansur
Published: May 2023

The house is a primary need that is not easily owned by everyone first for low-income people. This study aims to determine the implementation, inhibiting factors, and the impact of mortgage loans. This research was conducted because there has been no similar research that includes information from housing developers. The context for improving the welfare of the community has not yet been studied. This research is a qualitative research based on field research. Data were obtained from interviews with customers, banks, and housing developers. The results show that despite the difficulties in collecting housing loan requirements, it can help and make it easier for people to own a house. There are inhibiting factors, including public awareness, problems with checking BI, dishonesty in the community about salaries, insufficient filing, difficulty in obtaining salary certificates, non-strategic house locations, licensing regulations and bank regulations during the pandemic. Meanwhile, the impact of home ownership loans on customers is to increase the customer's obligations or debts in installments every month. For housing developers, subsidized housing loans make developers take longer to find a location for housing construction that fits the government budget. On the other hand, developers also failed to realize sales due to the pandemic. Meanwhile, for the Karanganyar State Islamic Savings Bank, subsidized housing loans made the obligation to return funds to the government increased. It can be concluded that subsidized ownership credit can help and facilitate low-income people in owning a house.
Co-culturing Chlorella vulgaris and Cystobasidium oligophagum JRC1 in the Microbial fuel cell (MFC) cathode for lipid biosynthesis.
Authors: Mishra Akanksha , Chhabra Meenu
Published: May 2023

This present study investigated the effect of co-culturing the photobiont and mycobiont in the microbial fuel cell (MFC) cathode for lipid generation. Chlorella vulgaris provides oxygen and nutrients for the yeast Cystobasidium oligophagum JRC1 while latter provides CO2 and quench oxygen for higher algae growth. Co-culture enhanced the lipid output of biomass by 28.33%. The total lipid yield and productivity with co-culture were 1.47 ± 0.18 g/L and 0.123 g/L/day respectively. The MFC attained open circuit voltage of 685 ± 11 mV. Synthetic wastewater was used at the anode with sodium acetate as a substrate. The power density of the system was 5.37 ± 0.21 mW m-2 with 75.88 ± 1.89% of COD removal. The total energy output (Lipid + Electrical energy) from the co-culture MFC was 11.5 ± 0.035 kWh m-3 which was 1.4-fold higher than algae alone.
A Real Time Optimization Based Sequential Convex Program for Pressure Management in Water Distribution Systems
Authors: Pham Dai Duc
Published: May 2023

Optimal pressure regulation to water leakage reduction in water distribution systems (WDSs) is one of the most priority tasks for water utilities worldwide. Mathematically, this engineering problem can be casted into a nonlinear program (NLP) where decision variables are valve settings and relative speeds of pumps. With given demand parameters, by formulating and and solving the NLP, control quantities will be computed and applied to the system for the control purpose. In practice, the demand parameters change continuously in time, and solving the formulated NLP requires a huge computation time, as a result, the control quantities obtained from the last NLP are remained to regulate the system until solution of the current NLP (with updated parameters) is available and so on. For this reason, how fast the solution of the NLP is deduced is vital for improving the control system performance. In this paper, we proposed to apply a new real time scheme based sequential convex program for computing approximated control profiles with respect to the change of water demand patterns. In particular, instead of solving the NLP with newly estimated demand pattern to full accuracy, only one convex NLP is solved in the computation framework of the sequential convex program (SCP) to get approximated solution with acceptable accuracy and in a near real time fashion. To demonstrate the efficacy of the real time optimization scheme, we apply it to determine fast control quantities for a real world WDS in Vietnam and one WDS benchmark for optimal pressure management. The results have demonstrated that, by applying such the optimization scheme, the obtained control profile gains acceptable accuracy as compared with the fully accurate one while the performance of control system is significantly enhanced.
Negative Indian Ocean Dipole drives groundwater recharge in southeast Australia
Authors: Rutlidge Helen , Taschetto Andréa , Andersen Martin , Baker Andy
Published: May 2023

Understanding how Australian groundwater recharge is affected by the Pacific and Indian Ocean climate drivers is crucial for water resource planning and management, especially in semi-arid environments. This will allow for assessment of the impact of climate change on the occurrence and timing of groundwater recharge and the sustainable management of this resource into the future. Measuring groundwater recharge is difficult as it occurs in the subsurface. However, caves situated in the unsaturated zone give us the opportunity to observe these subsurface processes. Here we show good agreement between the recharge events measured in a cave system and groundwater bores at a nearby site. We also show that the most significant recharge event during a decade of observations occurred during a particularly strong negative Indian Ocean Dipole period. Through further analysis of recharge events dating back 1900 we show for the first time a significant link with negative Indian Ocean Dipole events.
Investigating the Dynamic Spillover among Exchange Rate, Stock Market Index, Housing Price and Inflation in Iran: Does the Severity of Sanctions Matter?
Authors: Roudari Soheil , Ahmadian-Yazdi Farzaneh , Hammoudeh Shawkat , Rajabli Yasaman
Published: May 2023

This study investigates the effects of the dynamic spillover between exchange rate, stock market index, housing price, and inflation in Iran by using a TVP-VAR model that is based on Diebold and Yilmaz (2012) from March 2006 to January 2022). The results show that inflation is the most influential indicator in the network. But these results are different when it comes to the percentage of influence these four indicators have on the entire network. Also, research findings suggest that during the entire period of sanctions, the exchange rate has been the main channel of transmitting shocks to the network. Besides, the increase in the exchange rate has been the main factor in creating destructive fluctuations in Iran’s economy.
JEL Classification: E44, E31, G10, F51, C22
Predicting the size of the double-lumen tube in Asian women using ultrasound: A randomized controlled trial
Authors: Yao Minmin , Yang Yuying , Wang Ying , Zhao Zhimeng , Liao Qingwu , Liang Chao
Published: May 2023

Background Asian women are often faced with difficult intubation with double-lumen tube (DLT). Previous studies have illustrated that cricoid and left main bronchus diameter together can predict the DLT size better, but it will take extra computed tomography (CT) scans for the patients. We hypothesized that predicting the best-fit left double-lumen tubes (LDLTs) size, ultrasound will show better efficacy than CT without increasing intubating complications for Asian women.
Methods Our study enrolled 152 female patients undergoing elective thoracic surgery between March 2021 to October 2021. Patients were randomized into two groups: 75 in ultrasound group and 77 in the computed-tomography group. Patients in ultrasound group (US group) chosen the LDLT size according to the transverse diameter of the cricoid cartilage measured by ultrasound (TD-US). Controlled group based on the equivalent diameter of the left main bronchus (ED-LMB) measured by airway rebuilding of the helix CT (CT group).
Results The overall accuracy of LDLT was compared. The proportion of the appropriate DLTs was similar between two groups (78.7 vs. 67.5%, P =0.161). The number of inappropriate cases in CT group increased when height of Asian women is under 160 cm (P <0.05). US group showed less resistance to pass the glottis (P <0.001) and took shorter time in intubating (P =0.002).
Conclusion: Using ultrasound alone to select LDLT size has higher accuracy among Asian women less than 160 cm compared with CT.
Trial registration Chictr.org.cn, registration number: ChiCTR2100043764