bluuebunny/crossref_metadata_2025 huggingface dataset:
Basınç Dayanımı Açısından Püskürtme Beton Uygulamalarındaki Başlık Sistemlerinin Değerlendirmesi
Authors: POLAT Hasan , ÖZEL Cengiz
Published: December 2023

Bu çalışmada, farklı başlık tiplerinin püskürtme betonunun basınç dayanımı üzerindeki etkisi incelenmiştir. Yapılan bu çalışmada, başlıksız (kontrol), kükürt başlıklı ve neopren başlıklı olmak üzere üç farklı başlık sisteminin etkisi değerlendirmiştir. Deneyler kapsamında her bir başlık sistemi için dokuz farklı numune üzerinde testler gerçekleştirilmiştir. Elde edilen sonuçlar, başlıksız numunelerin kükürt başlık ve neopren başlığa kıyasla daha düşük basınç dayanımı gösterdiğini belirlenmiştir. Bu sonuçlar, başlık kullanımının önemini vurgulamaktadır. Ayrıca, kükürt başlık sistemine alternatif olarak sunulan neopren başlığın, kükürt başlık sistemine göre % 2.96 daha yüksek ortalama basınç dayanımı değeri sunduğu belirlenmiştir. Bu durum, numune başlık birleşim bölgelerinde oluşan gerilme yığılmalarından kaynaklanabileceği şeklinde yorumlanmıştır. Çalışmanın sonuçları, püskürtme betonunun başlık seçiminin ve başlık-beton etkileşiminin, malzemenin basınç dayanımı özellikleri üzerinde önemli bir rol oynayabileceğini göstermektedir. Sonuç olarak günümüzde laboratuvarda yaygın olarak kullanılan kükürt başlıklamaya alternatif olarak neopren başlık sistemlerin tavsiye edilebileceği sonucuna varılmıştır.
VERIFIKASI PENGUKURAN RADIOAKTIVITAS 153Sm MENGGUNAKAN DOSE CALIBRATOR MULTITIPE
Authors: Pertiwi Ligwina Dita , Maskur Maskur , Yanto Yanto , Fairusya Nuha , Ekaningsih Nuri Jannati Wahyu
Published: December 2023

Verifikasi pengukuran dilakukan untuk menjaga validitas data hasil pengukuran. Pada penelitian ini telah dilakukan verifikasi pengukuran radioaktivitas 153Sm menggunakan alat dose calibrator dengan lima tipe yang berbeda, yaitu dose calibrator Atomlab 100, Atomlab 300, Atomlab 400, Atomlab 500, dan Capintec CRC-tr5. Parameter verifikasi meliputi akurasi, presisi, kelinieran, Limit of Detection (LOD), dan Limit of Quantification (LOQ). Pada pengujian akurasi, alat dose calibrator Atomlab 300 ditetapkan sebagai alat standar untuk menguji akurasi hasil pengukuran alat yang lain. Hasil verifikasi menunjukkan bahwa semua alat ukur memiliki error akurasi kurang dari 3%, namun setelah dilakukan uji t, ternyata hanya dose calibrator Atomlab 400 yang nilai thitung kurang dari ttabel, sedangkan Atomlab 100, Atomlab 500, dan Capintec CRC-tr5 thitung lebih besar daripada ttabel. Pada uji presisi diperoleh hasil bahwa kelima tipe alat dose calibrator memiliki presisi yang baik. Kelima alat tersebut memiliki nilai kelinieran yang baik untuk pengukuran Sm-153 radioaktivitas 20-140 mCi. Nilai LOQ dose calibrator Atomlab 100 = 8,48 µCi, Atomlab 300 = 5,08 µCi, Atomlab 400 = 8,66 µCi, Atomlab 500 = 8,78 µCi, dan Capintec CRC-tr5 = 7,23 µCi. Nilai LOD Dose calibrator Atomlab 100 = 2,54 µCi, Atomlab 300 = 1,52 µCi, Atomlab 400 = 2,59 µCi, Atomlab 500 = 2,64 µCi, dan Capintec CRC-tr5 = 2,17 µCi. Hal ini menunjukkan bahwa kelima alat tersebut memiliki validitas pengukuran yang baik dengan kepercayaan pengukuran 95%, namun untuk Atomlab 100, 500, dan Capintec CRC-tr5 hasil pengukurannya perlu dikalikan faktor koreksi.Kata kunci: Dose calibrator, verifikasi, radioaktivitas, 153Sm
Исследование и оптимизация рубашки жидкостного охлаждения электродвигателя под аддитивное производство
Authors: Еременко Владислав Викторович , Исмагилов Флюр Рашитович , Красноперов Даниил Германович , Михайлов Алексей Евгеньевич , Михайлова Александра Борисовна , Горюхин Максим Олегович
Published: December 2023

Проведены исследования по формированию облика жидкостной рубашки охлаждения для электромашины с номинальной мощностью 220 кВт. Для оценки эффективности рубашек охлаждения проведен комплекс CFD-расчетов традиционной и перспективной конфигурации в программном комплексе Ansys CFX. Оптимизация осуществлена на основе двухзаходной спиральной рубашки охлаждения путем введения различных ребер и штырьков-турбулизаторов. В результате проведенных исследований определено, что традиционная винтовая рубашка охлаждения не позволяет обеспечить требуемое качество терморегулирования при заданных граничных условиях и ограничениях, а применение двухзаходной спиральной рубашки охлаждения позволяет существенно улучшить тепловое состояние конструкции, однако для достижения заданных требований следует адаптировать конструкцию за счет внедрения дополнительных ребер и штырьков-турбулизаторов. Предложенная финальная топология спиральной двухзаходной рубашки охлаждения с увеличенными ребрами, дополнительными ребрами в каналах вокруг входной и выходной области и штырьками-турбулизаторами вокруг выходной области позволяет обеспечить качественное терморегулирование конструкции с удовлетворением требования по максимальной температуре статора электрической машины не более 200°С. Данное исследование продемонстрировало преимущества рубашек жидкостного охлаждения со сложной геометрической конфигурацией и локальной интенсификацией теплообмена за счет внедрения ребер и штырьков-турбулизаторов, которые могут быть изготовлены с применением аддитивных технологий.
Structural performance of expanded polystyrene panels as an alternative building system
Authors: Silva Maurício Macedo da , Lima Douglas Mateus de , Silva Luccas André Felix , Medeiros Iálysson da Silva
Published: December 2023

Single lightweight panels of expanded polystyrene (EPS), known as sandwich EPS panels, or simply EPS panels, have emerged as a building system that complemented the conventional one. In this context, this study develops an architectural and structural design for a residence with sandwich EPS panels as a building system. To set the features of the project, we chose a plot in the city of Petrolina-PE and used the SAP2000 software for the structural modeling to establish the efforts to which the walls would be subjected. The structural elements were dimensioned based on the NBR6118:2014 and the crack opening was verified according to the NBR11173:1990. Due to the small overlapping of the walls in the architectural design, the building system needed to be integrated into EPS with beams and pillars of reinforced concrete. Most of the pillars presented minimum reinforcement, while the slabs showed a reinforced lattice beam pattern. In turn, the beams presented dimensions and robust reinforcements due to the higher values of the bending moments obtained. Despite the satisfactory results, further studies should investigate this building system, as well as the national standardization and implementation of specific modeling programs.
Dialogues between the rehabilitation of buildings and the sustainable development of consolidated metropolises
Authors: Ferreira Rodrigo de Paula , Sígolo Letícia Moreira
Published: December 2023

With the 2030 Agenda, the nations that ratified the Paris Agreement have taken steps towards achieving Sustainable Development. Certain strategies have been identified as determining factors to meet the goals outlined in the Sustainable Development Goals (SDG) Number 11. In this context, consolidated cities have buildings that do not meet contemporary needs, being, in many cases, underutilized or in obsolescence integral. This article examines two case studies: the Pruitt-Igoe residential complex built in the city of St. Louis, in the USA and the Wilton Paes de Almeida building, built in the city of São Paulo, in Brazil. Both examples of modern architecture were lost in the context of contemporary metropolises. The study discusses the retrofitting of these urban structures of the metropolises, in the perspective of the 2030 Agenda, highlighting the need to expand the measures of rehabilitation of buildings as a strategy for a Sustainable Development, in order also to reduce the existing idleness built in the areas centers with the use of existing resources and reduce the spread of the urban area that assigns the extremes to the most vulnerable in the context of the São Paulo metropolis. With this analysis, the article seeks to demonstrate that investment in in retrofitting techniques can be a favorable alternative to Sustainable Development and the regeneration of metropolises.
Active Mobility and Space Syntax in the city of Blumenau/SC
Authors: Pereira Edilson
Published: December 2023

This research addresses aspects related to active mobility and its relationship with space syntax. Active mobility is a preponderant factor in the quality of urban space, since it is about the characteristics and conditions that a place presents for walking. In this context, this research aims to correlate, under the light of Space Syntax, the results obtained in the evaluation of active mobility with the configurational pattern of 4 spatial clippings of the city of Blumenau/SC. Through the evaluation results that identified active mobility indexes for each area, and the angle analysis of metric integration, in radius of 500, 1000 and 1500 meters, if you can concluded that the active mobility indexes in the researched areas present better results in the areas where the configurational pattern is more integrated, in detriment of the segregated ones.
OTOMOTİV ENDÜSTRİSİNDE KOMPOZİT MALZEME KULLANIMI
Authors: AĞIRGAN Mehtap
Published: December 2023

Otomotiv endüstrisinde kompozit malzeme kullanımı 80 yıllık bir geçmişe dayanmaktadır. Kompozit malzemeler; araçların tasarımında kolaylık sağlaması ve çevreci olmaları nedeni ile tercih edilmektedir. Küresel ısınma nedeni ile ülkelerin net emisyonu sıfıra indirme sözü bulunmaktadır. 2030 yılında Avrupa da ise otomobillerin karbondioksit emisyonlarını yarı yarıya azaltması beklenmektedir. Ayrıca günümüzde otomobillerin performansı yüksek, emniyetli, ucuz, çok işlevli ve tarz sahibi bir tasarıma sahip olmasının yanı sıra yakıt tasarruflu ve karbon salınımının düşük olması gibi çevreci özelliklere sahip olması da istenmektedir.

Bu çalışmada Otomobillerde kullanılan kompozit malzemelerin tanımı, tarihçesi, sektörde kullanım yerleri, günümüzde ve gelecekte otomotiv sektöründeki kompozit malzemelerin durumları hakkında bilgi verilmiştir.
Early Life Nutrition during the First 1000 Days from a Malaysian Perspective
Authors:   Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, 56000 Kuala Lumpur, Malaysia.
Published: December 2023

The first 1000 days of life, encompassing the period from conception to a child’s second birthday, represents a pivotal phase in human development. This review paper highlighted the importance of this critical window with a comprehensive analysis exploring the multifaceted impact of nutrition during the three distinct phases: the pregnancy-intrauterine period, early infancy-breastfeeding period, and early childhood-complementary feeding period. Within the pregnancy-intrauterine period, the maternal body mass index emerges as a crucial factor, directly affecting the well-being of both mother and child. Optimal nutrition, including essential micronutrients such as folic acid, iron, iodine, and vitamin D, are imperative to mitigate the risk of neural tube defects and related disorders, which remain a concern in Malaysia. Exclusive breastfeeding during the initial six months of life is identified as a cornerstone of infant development, nurturing both the child’s cognitive abilities and immune system. Timely introduction of complementary foods is equally vital, acting as a safeguard against childhood obesity and undernutrition. This review paper provided an in-depth examination of the importance and critical role of nutrition in the first 1000 days of life. It further outlined the current status, recommended strategies and interventions to improve child nutrition during this crucial phase in the Malaysian context.
Validity and Reliability of an Adapted Questionnaire Measuring Acceptance of Traditional Chinese Medicine among Cancer Patients
Authors:   Department of Chinese Medicine,  M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, LOT PT 21144, Jalan Sungai Long, Bandar Sungai Long, 43000, Kajang, Selangor, Malaysia.
Published: December 2023

Acceptance of traditional chinese medicine (TCM) treatment is important in cancer patients to improve treatment efficacy, reduce side effects and prolong prognosis and survival rate. However, such studies and validated instruments that assess the acceptance of TCM treatment in Malaysia are limited. This study aimed to evaluate the validity and reliability of the acceptance of the TCM treatment questionnaire based on applying the Theory of Planned Behaviour. The validation study was conducted in two phases. The first phase included content validation, adaptation and face validity using the Survey Validation Rubric for Expert Panel (VREP). The second phase included construct reliability by using Cronbach alpha. The first phase validation of the questionnaire met expectations from the experts’ panel with a score of 3.33. In phase two, 78 patients were included in the analysis. All constructs achieved a Cronbach Alpha >0.8, showing good reliability of the questionnaire. This study demonstrated good validity and reliability of the major constructs in the acceptance of the TCM questionnaire. Our results showed that the acceptance of the TCM questionnaire was a reliable instrument that could be applied to evaluate the acceptance of TCM treatment among cancer patients.
Perception and Attitude of Undergraduate Medical Students and Lecturers towards the Problem-Based Learning of Universiti Kebangsaan Malaysia Medical Curriculum: An Inter-University Study
Authors:   Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, 56000 Kuala Lumpur, Malaysia.
Published: December 2023

Problem-based learning (PBL) is a student-centred approach by using clinical scenario to achieve the learning objectives. This study aimed to determine the perception and attitude of Universiti Kebangsaan Malaysia (UKM) and Maldives National University (MNU) undergraduate medical students and lecturers towards PBL in UKM curriculum. A cross-sectional study was conducted by using online self-administered questionnaires based on a five-point Likert scale. The questionnaires were validated with Cronbach’s alpha of 0.907 and 0.703 for students and lecturers respectively. A total of 179 UKM and 61 MNU students, and 67 UKM lecturers and 8 MNU lecturers were recruited in the study. 86.69% and 69.87% of students had positive scores in perception and attitude assessment respectively. However, no significant differences were observed in median and mean scores for perception and attitude between gender, university, year of study, and cumulative grade point average (CGPA) of the respondents. For lecturers, 63.62% and 85.83% had positive scores for perception and attitude respectively. The attitude score among MNU lecturers was significantly higher than UKM lecturers. In conclusion, both students and lecturers showed positive perceptions and attitudes towards PBL of the UKM curriculum which gave benefits and contribution in enhancing knowledge, learning and soft skills.
Medical Educationduring COVID-19: Association between e-Learning Practice and Mental Health Status of Medical Students in Universiti Kebangsaan Malaysia
Authors:   Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.
Published: December 2023

The emergence of Coronavirus disease 2019 (COVID-19) pandemic forced the Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM) to ensure the transition from face-to-face learning to online teaching for continuity of education. This study aimed to investigate the association between e-learning and mental health status of UKM medical students. A cross-sectional study was carried out among Years 4 and 5 UKM medical students. Participants were randomly selected from a registered list. Students’ perceptions of e-learning usage prior to and during COVID-19 pandemic and its relation to mental health status were assessed using The World Health Organisation Quality of Life (WHOQOL-BREF) and Hospital Anxiety and Depression Scale (HADS) questionnaires. Mean scores for depression were 5.35 (SD 3.38) and anxiety 6.48 (SD 3.36). The frequency of e-learning usage per week was increased during COVID-19 compared to pre-COVID period (p=0.045). Comparing the four domains of quality od life (QOL), psychological health had the lowest mean score of 62.63 (SD 15.22) while the environmental domain was the highest 69.34 (SD 10.92). Total QOL scores were significantly correlated with depression (p<0.001) and anxiety (p<0.001). This study provided insights into the effect of e-learning practice on medical students’ mental health status. A significant increase in e-learning usage during COVID-19 was observed.
Minimally invasive management of a giant paratubal cyst
Authors: ERİÇ HORASANLI Jule , METİN Ülfet Sena
Published: December 2023

Paraovarian or paratubal cysts are located between the ovary and the fallopian tube. They are usually benign and paratubal cysts are defined as a giant when they cross the 150 mm threshold. Open surgery is generally preferred in large cysts due to the difficulty of exploration. In our case, the size of the cyst was reduced by evacuating the transabdominal, and it was made easy to visualize. The cyst capsule was detached, the overlying tube was left intact, and fertility preservation was achieved.
A clinical case series of Rickettsia spp. from southern Türkiye
Authors: YEŞİL Edanur , ÖZGÖKÇE ÖZMEN Berfin , AKÇA Mehtap , KAYABEY Özlem , KUYUCU Necdet
Published: December 2023

Rickettsial infections should be considered in the presence of a maculopapular rash, especially in the endemic area with a history of tick bite. In this study, Rickettsia spp. infections of three cases will be mentioned. Three cases with positive Rickettsia spp immunofluorescent antibody serology were included in the study. Case-1 was a 17-year-old male patient, who had a history of tick bite one week before the admission was admitted with chest pain. He had tachycardia and a "tache noir" rash with a necrotic center in the area of the tick bite. Laboratory parameters showed lymphopenia, cardiac enzymes elevation. The patient’s serelogy of Rickettsia conorii IgM was 1/192 titer positive and IgG was negative. He hospitalized as acute Mediterranean Spotted Fever myocarditis. He recovered with doxycycline treatment. Case-2 was a nine-month-old girl presented with fever, rash and lymphadenomegaly on left axilla two weeks after the tick bite of her left arm. The rash was localized to the arm. R. slovaca and R. aeschlimannii serologies were detected 1/40 titer positive. After ciprofloxacin treatment her symptoms had dissapeared. Case-3 was a seven-year-old girl presented with fever reaching 39ºC for five days, myalgia and rash all over her body. She had scratched the tick from the scalp five days before the admission. Rickettsia conorii IgM serology was 1/768, IgG was 1/640 titer positive. She recovered after doxycycline treatment. Rickettsia spp. infections can lead to infections like myocarditis or the spotted fever group Rickettsiosis diseases. Complications can be prevented with early diagnosis and treatment.
Рак мочевого пузыря
Authors: Гладков О. А. , Булычкин П. В. , Волкова М. И. , Зуков Р. А. , Матвеев В. Б. , Носов Д. А.
Published: December 2023

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Особенности лекарственной терапии при солидных опухолях на фоне беременности
Authors: Стенина М. Б. , Пароконная А. А. , Полушкина Е. С. , Ульрих Е. А. , Хохлова С. В. , Шмаков Р. Г.
Published: December 2023

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Анемия при злокачественных образованиях
Authors: Орлова Р. В. , Гладков О. А. , Кутукова С. И. , Копп М. В. , Королева И. А. , Ларионова В. Б. , Моисеенко В. М. , Поддубная И. В. , Птушкин В. В.
Published: December 2023

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Eylem ve Katılım İlişkisi Açısından Siyasal İletişim, Dijital Propaganda ve Sosyal Medya
Authors: ÖZER Mehmet Akif , KARTAL Meryem
Published: December 2023

Literatürde siyasal iletişim, toplumsal yaşam ve temsil sistemi arasında özerk bir alan olarak kamuoyunun siyaset ile ilişkiye geçtiği, siyasetçilerin ve siyasal partilerin devreye girdiği bir süreç olarak bilinir. Siyasal iletişimle birlikte bu çalışmanın odağında yer alan dijital propaganda ise yeni ve farklı tekniklerin özellikle sosyal ağlar ve internet ortamında dijital platformlarda uygulanmasını öngörür. Bu ortamda Facebook, Twitter gibi sosyal medya araçları en etkili dijital propaganda ortamları olarak hız, kitlesellik ve etkileşim açısından çok fazla tercih edilmektedir. Bu kapsamda çalışmanın temel amacı propagandayı sosyal medya düzeneği içinde ele alarak eylem ve katılımla ilişkisini incelemektir. Çalışmada söz konusu bu çerçevede dijital kültürün yol açtığı dönüşüm; sosyal medya ortamında kültürel, siyasal, ekonomik boyutlarıyla incelenmiştir. Öncelikle teorik çerçeve ortaya konmuş ardından propagandanın sanal boyutta nasıl kullanıldığı tartışılmıştır. Ardından dijital propaganda ve sosyal medya ilişkisi, ağ toplumu, dijital kültür ve dijital vatandaş konuları değerlendirilmiştir. Sonuçta çalışmanın temel tezi doğrultusunda dijital propaganda ekseninde gelişen katılım ve eylemlerin teorik temeli belirlenmeye çalışılmıştır. Çalışmada bu şekilde bireyin dijital çağda teknolojisi ile olan ilişkisi irdelenerek sosyal medyanın yeni sosyalleşme aracı olduğuna da vurgu yapılmaktadır. Bu doğrultuda çalışmada literatür taraması yapılmış ve araştırmanın sonunda da dijital propagandanın içerik, hedef kitle, amaç ve kaynak gibi faktörler bakımında geleneksel propagandadan oldukça farklı olduğu sonucuna ulaşılmıştır.
Secondary metabolites of plants and their possible role in the “age of superbugs”
Authors: Nesterovich V.M. , Belykh D.A. , Gorokhovets N.V. , Kurbatov L.K. , Zamyatnin A.A. , Ikryannikova L.N.
Published: December 2023

Bacterial infections are a serious cause of high morbidity and mortality worldwide. Over the past decades, the drug resistance of bacterial pathogens has been steadily increasing, while the rate of development of new effective antibacterial drugs remains consistently low. The plant kingdom is sometimes called a bottomless well for the search for new antimicrobial therapies. This is due to the fact that plants are easily accessible and cheap to process, while extracts and components of plant origin often demonstrate a high level of biological activity with minor side effects. The variety of compounds obtained from plant raw materials can provide a wide choice of various chemical structures for interaction with various targets inside bacterial cells, while the rapid development of modern biotechnological tools opens the way to the targeted production of bioactive components with desired properties. The objective of this review is to answer the question, whether antimicrobials of plant origin have a chance to play the role of a panacea in the fight against infectious diseases in the “post-antibiotic era”.
A dual-vector phospholipid nanosystem of doxorubicin: accumulation and cytotoxic effect in breast cancer cells in vitro
Authors: Tereshkina Yu.A. , Bedretdinov F.N. , Kostryukova L.V.
Published: December 2023

Various chemotherapeutic agents are used to treat breast cancer (BC); one of them is the anthracycline antibiotic doxorubicin (Dox), which, in addition to its cytostatic effect, has serious side effects. In order to reduce its negative impact on healthy organs and tissues and to increase its accumulation in tumors, Dox was incorporated into phospholipid nanoparticles. The additional use of vector molecules for targeted delivery to specific targets can increase the effectiveness of Dox due to higher accumulation of the active substance in the tumor tissue. The integrin αvβ3, which plays an important role in cancer angiogenesis, and the folic acid receptor, which is responsible for cell differentiation and proliferation, have been considered in this study as targets for such vector molecules. Thus, a phospholipid composition of Dox containing two vector ligands, cRGD peptide and folic acid (NPh-Dox-cRGD-Fol(3,4)), was prepared. Study of the physical properties of the developed composition NPh-Dox-cRGD-Fol(3,4) showed that the average particle size was 39.62±4.61 nm, the ζ-potential value was 4.17±0.83 mV. Almost all Dox molecules were incorporated into phospholipid nanoparticles (99.85±0.21%). The simultaneous use of two vectors in the composition led to an increase in the Dox accumulation in MDA-MB-231 BC cells by almost 20% as compared to compositions containing each vector separately (folic acid or the cRGD peptide). Moreover, the degree of Dox internalization was 22% and 24% higher than in the case of separate use of folic acid and cRGD peptide, respectively. The cytotoxic effect on MDA-MB-231 cells was higher during incubations with the compositions containing folic acid as a single vector (NPh-Dox-Fol(3,4)) and together with the RGD peptide (NPh-Dox-cRGD-Fol(3,4)). Experiments on the Wi-38 diploid fibroblast cell line have shown a significantly lower degree of cytotoxic effect of the phospholipid composition, regardless of the presence of the vector molecules in it, as compared to free Dox. The results obtained indicate the potential of using two vectors in one phospholipid composition for targeted delivery of Dox.
Cybersecurity in a single algorithmic space of distributed computing and in a global computer environment
Authors: Меджидов З.У.
Published: December 2023

Цель статьи – исследовать кибербезопасность в едином алгоритмическом пространстве распределенных вычислений с учетом особенностей развития глобальной компьютерной среды. Для достижения цели исследования использованы методы обобщения, анализа, синтеза. Выделяются фундаментальные проблемы интеграции разнородных ресурсов глобальной компьютерной среды. Показаны причины разнородности и пути устранения ее негативных последствий. В применении к распределенным социотехническим системам определены основные понятия сетецентрического управления. Излагаются принципы формирования в глобальной компьютерной среде математически однородного алгоритмического пространства распределенных вычислений и сетецентрического управления. Обсуждаются системообразующие возможности нового пространства: бесшовная программируемость, кибербезопасность и надежность распределенных вычислений. Обосновывается необходимость построения новой элементной базы в виде массовых однокристальных сетевых компьютеров с немикропроцессорной архитектурой. После устранения фундаментальных причин разнородности открываются возможности формирования в глобальной компьютерной среде математически однородного, бесшовно программируемого и кибербезопасного алгоритмического пространства распределенных вычислений для целостного решения сильносвязных задач сетецентрического управления сколь угодно большими социотехническими системами.

The purpose of the article is to study cybersecurity in a single algorithmic space of distributed computing, taking into account the developmental features of the global computer environment. To achieve the goal of the study, the methods of generalization, analysis, and synthesis were used in the work. Fundamental problems of integration of heterogeneous global computer environment resources are singled out. The causes of heterogeneity and ways to eliminate its negative consequences are shown. As applied to distributed socio-technical systems, the basic concepts of network-centric control are defined. The principles of formation in the global computer environment of a mathematically homogeneous algorithmic space of distributed computing and network-centric control are outlined. The system-forming possibilities of the new space are discussed: seamless programmability, cybersecurity and reliability of distributed computing. The necessity of building a new element base in the form of mass single-chip network computers with a non-microprocessor architecture is substantiated. It is shown that, by eliminating the fundamental causes of heterogeneity, they open up the possibility of forming in the global computer environment a mathematically homogeneous, seamlessly programmable and cyber-safe algorithmic space of distributed computing for a holistic solution of strongly connected network-centric control problems by arbitrarily large sociotechnical systems.
Desperdicio de alimentos en la alimentación escolar, currículo, hábitos y comportamientos en América Latina. Una revisión sistemática.
Authors: Hernández Rangel Sandra Helena
Published: December 2023

Introduction: In Latin America, the School Feeding Program (PAE) providesthe service during the school year, to more than 40 million students,however, despite the benefits of this program to combat hunger andpoverty, environmental effects and the cultural problem of food waste atschool arises, a problem that is the co-responsibility of the actors involvedin the PAE. The purpose of this systematic review is to present the findingsafter identifying studies, analyzing research trends and knowledge gapsabout the educational actions and strategies proposed in the study plansand developed within the school, in Latin American countries, with inorder to reduce food waste produced in the PAE. Methodology: 34 studiespublished in the Scopus, Dialnet, Academic search, ProQuest, Scielo,Semantic Scholar and google scholar, databases were selected based oninclusion and exclusion criteria, in Spanish, Portuguese and English. Whichwere organized under the PRISMA guide Results and discussion: The reviewgave rise to four categories or lines of research around food waste in schools,which are: education, programs and policies, responsible consumption andcurriculum, the research explores the need to address food waste food in theeducational field and to generate educational actions aimed at mitigating it.Conclusions: The review reveals knowledge gaps, particularly in successfulproposals that lead to mitigating food waste, in the same way it is necessaryto investigate the behaviors of students that lead to the maintenance of thecultural practice of food waste.
Randomized controlled trial comparing the effectiveness of tamsulosin, tamsulosin with tolterodine and double J stent position in controlling stent related symptoms after ureteroscopic lithotripsy
Authors: Agbo Christian A. , Nahar Guavar
Published: December 2023

Background: Objective of the study was to determine the effect of stent position and medications in preventing stent-related symptoms.
Methods: This was a prospective study conducted at Meenakshi Mission Hospital and Research Centre Madurai, Tamil Nadu, India. 150 patients who underwent ureteroscopic lithotripsy with indwelling stent were distributed into three groups. On demand analgesics were given to group 1 (n=50), Tamsulosin 0.4 mg daily for group 2 (n=50) and tamsulosin 0.4 mg and tolterodine 4 mg daily for group 3 (n=50). The patients were also subclassified into appropriate or inappropriate group according to stent position. All patients completed various domains of Ureteral stent symptom questionnaire (USSQ) on 1st and 7th postoperative days. Appropriate tests statistics were performed using EPI-Info statistical software package.
Results: In control group, patients with appropriate stent position had significantly lower symptom scores than those with inappropriate stent position (p value~0.0001) in all domains of USSQ except global quality of life score (p value=0.08). Addition of tamsulosin 0.4 mg (group 2) had superadded beneficial effect in appropriate position group, but not in patients with inappropriately positioned stents. Patients taking both tamsulosin 0.4 mg and tolterodine 4 mg (group 3) had no significant improvement in symptom scores in appropriate position group (all domains of USSQ) and inappropriate position group (most domains).
Conclusions: Appropriate stent position is the most important independent factor than medications in preventing stent related symptoms; tamsulosin has superadded benefit in patients with correctly positioned stents.
Assessment of risk factors in patients undergoing difficult cholecystectomy: a cross-sectional study at a tertiary care hospital in Central India
Authors: Chandak Unmed , Chauhan Kapil , Gupta B. B. , Mitra Arti , Bansod Prasad , Upadrashta Rohit , Mundhada Aditi
Published: December 2023

Background: Laparoscopic cholecystectomy (LC) is the operation of choice in the treatment of symptomatic gallstone disease. Most of the time, the levels of difficulties are hard to assume. The risk factors for difficult LC have not been adequately evaluated in Indian population, especially with respect to western Indian population. Thus, the present study was undertaken to assess the risk factors in patients undergoing difficult cholecystectomy.
Method: The study involved 100 adult patients with cholelithiasis admitted in the department of surgery for cholecystectomy over a period of 2 years from Nov 2020 to Dec 2022. Preoperatively, patients were evaluated for risk factors including age, gender, BMI, history of sickle cell disease, previous abdominal surgery, presence of pericholecystic collection, gall bladder thickness, impacted calculi, adhesions in triangle of Calot‘s, and previous hospitalization for acute cholecystitis and acute pancreatitis. These factors were assessed to predict difficult LC.
Results: Majority of laparoscopic procedures were easy (65%), while remaining were difficult (35%). Difficult cholecystectomy was significantly associated with age ≥50 years (p=0.016), male gender (p=0.031), BMI ≥25 kg/m2 (p<0.0001), sickle cell disease (p=0.030), previous abdominal surgery (p=0.004), pericholecystic collection (p=0.017), gall bladder thickness ≥4 mm (p=0.007), adhesion in triangle of Calot‘s (p<0.0001), impacted calculi (p=0.036), previous hospitalization for acute cholecystitis and acute pancreatitis (p<0.0001) and diabetes mellitus (p<0.0001). The conversion rate was 2%.
Conclusions: An awareness about reliable predictors for difficult LC would be helpful for an appropriate treatment plan and application of the resources to anticipate difficult LC. However, further studies with larger sample size are required to confirm the findings.
Migration of intraventricular sol within the lateral ventricles: the unusual mouse within the ventricle
Authors: Patel Ankit B. , Ranade Deepak , Reddy Rajeev , Aziz Ramis A.
Published: December 2023

Intraventricular tumor is very rare presentation in brain. In our article we present very rarely seen intraventricular tumor in child which migrate during the changing the position of head. So we call it “mouse in the brain”. This case is challenging for the neurosurgeon to operate without any advance infrastructure like intra-operative ultra sound machine or portable computed tomography (CT) scan.
Strangulated direct hernia loop perforation in a COVID positive patient: a case report
Authors: Banerjee Divya J. , Shah Viral , Chauhan Himesh R.
Published: December 2023

A strangulated hernia occurs when the blood supply to the contents of the hernia (e.g. omentum, bowel) is compromised and may lead to bacterial translocation and intestinal wall necrosis (potentially resulting in bowel perforation). This condition significantly increases the risk of emergency hernia repair which may increase the incidence of surgical site contamination and recurrence. We report a 28-year old male who presented in the emergency with right inguinal abdominal pain for the past 5 days which increased suddenly in the last 2 days, associated with abdominal distension, constipation with 2 episodes of vomiting. During surgery, the hernia was found to be a direct one containing a strangulated perforated loop of the terminal ileum, a rather uncommon finding in a direct hernia. Resection anastomosis of the perforated segment of the bowel was performed with uneventful intraoperative and postoperative courses.
The effectiveness of exercises in patients with thumb carpometacarpal osteoarthritis: a study protocol for a systematic review and meta-analysis
Authors: Karanasios Stefanos , Mertyri Dimitra , Karydis Fotis
Published: December 2023

Background: The thumb carpometacarpal osteoarthritis (CMC-OA) is a common musculoskeletal condition of the hand causing increased pain and significant disability. Although different modes of exercises are usually prescribed during the management of the condition, the evidence for their effectiveness is sparse. The aim of this protocol is to investigate through a systematic review the effectiveness of exercises compared with other non-surgical interventions in reducing pain and improving function in the management of the thumb CMC-OA.
Methods: We will conduct this systematic review following the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines. PubMed, CINAHL, EMBASE, PEDro, ScienceDirect, Cochrane Library, Grey literature databases and clinical trial registries will be searched. Two reviewers will independently evaluate the retrieved results. Subsequently, data extraction of the eligible trials will be conducted by two independent researchers. We will use the grading of recommendations assessment, development, and evaluation (GRADE) approach to assess the certainty of evidence.
Conclusions: This systematic review will provide evidence for the clinical benefits of exercises compared with other conservative interventions in the management of patients with thumb CMC-OA.
Trial registration: PROSPERO registration number is CRD42023461505.
Long term outcome of presurgical infant orthopaedics in patients with cleft lip and palate: A systematic review and meta-analysis
Authors: Banari Ashwina S , Datana Sanjeev , Chopra SS , Agarwal SS
Published: December 2023

To evaluate the long term outcome of Presurgical Infant Orthopaedics (PSIO) in patients with Cleft Lip and Palate (CLP).

A systematic literature search was performed according to PRISMA guidelines of articles from Jan 2011 till Feb 2021, using PubMed, Cochrane database and manual searching in the institutional library. Fifteen articles which met the inclusion and exclusion criteria were ranked according to the Oxford Centre for Evidence based Medicine – Levels of Evidence. The quality assessment of selected systematic reviews was done with ROBIS tool. Studies included for meta-analysis were analyzed with Q statistic methods, I index, fixed-effects, DerSimonian-Laird Random effects and Begg-Mazumdar bias indicator.

Selected fifteen articles were qualitatively assessed for various parameters on long term outcome of PSIO (minimum of 5 years), showed a positive outcome in nasolabial and pharyngeal airway parameters. Due to heterogeneity in the studies, meta-analysis was carried out for five studies in which nasolabial aesthetics parameters showed a significant improvement in PSIO group compared to control group (Q Statistic : 569.52523, P-value<0.001).

The PSIO in patients with CLP shows significant positive changes in nasolabial aesthetics and pharyngeal airway on a long term. These results should be considered with caution as the heterogeneity of included studies cannot be denied. Hence, more controlled and well conducted studies should be performed, focussing on the individual parameters for long term outcome of PSIO.
Evaluation of stress in bone by 9 different mini implants based on placement angle with relation to enmasse retraction force - An FEM study
Authors: Yenaganti Sai Teja , Aggarwal Ankur , Misra Vaibhav , Sharma Prashant , Yadav Deepanshi , Irengbam Devina
Published: December 2023

The aim of this study was to evaluate the stress in bone at the mini implant site, placed at 5 different insertion angles with relation to en-mass retraction force using a Finite element analysis.

Evaluation of stress in bone and their distribution pattern at the mini implants. Evaluation of stress distribution in surrounding cortical bone on application of retraction force at 5 different insertion angle.

Force applied was 200 grams on the model. The mini implants were modelled with varying diameters (1.3mm, 1.6mm, and 2.3mm) and varying lengths (7mm, 8mm, 10mm). The implant insertion angulations used were 30°, 45°, 60°, 90°, 120°.The pitch of the implant thread used was 0.5mm. This was fixed in all implant designs in this study. After the models were created, a process called meshing in which the models were divided individually into a finite number of elements,. The model was meshed with a tetrahedral configuration. The complete geometry has an assembly of discrete pieces called elements and is connected to gather at a finite number of points called nodes.

In bone Von Mises stress was high in 1.3 × 8 mm implant at 60angulation and least was in 2.3 × 7 mm implant at 30angulation. In Implant of 1.3 × 10 mm in 90angulation showed high Von Mises stress and in Implant of 2.3 × 8 mm in 30angulation showed least Von Mises stress.

Mini implant which has got smaller diameter, long length and high inclination angle showed higher stresses when compared to other mini implants.
Artificial intelligence-based automated model for prediction of extraction using neural network machine learning: A scope and performance analysis
Authors: Trehan Mridula , Bhanotia Deeksha , Shaikh Tarannum Alam , Sharma Shivangi , Sharma Sunil
Published: December 2023

To compare the Artificial Intelligence based model & conventional technique for prediction of extraction in orthodontic treatment plan.

A comparative study was conducted on total 700 patients, who were divided into training set and testing set based on simple random sampling by means of computer generated random numbers. The photographs of the 630 patients [training set] along with the treatment plan finalized for them based on Arch Perimeter & Carey’s Analysis, was fed in the AI model [convolutional neural network (ResNet-50)] in order to train it for the stipulated function of eventually predicting the treatment plan in the testing set [70 patients], based on the input of the right profile photographs. The accuracy of measurement of the parameters of these seventy test set patients by the machine learning model relative to the manual method was compared eventually. Using the Statistical Package for Social Sciences, the acquired data was statistically analyzed, and p <0.05 was deemed statistically significant. The normality of the data was examined using the Shapiro-Wilks test and the Kolmogorov-Smirnov test. Depending on the collected data and normality assessed, appropriate reliability was estimated.

The analysis of 70 test patients showed that 65.12% of the total extraction cases and 62.96% of the total non-extraction cases (as predicted by the AI model) were in agreement with the results of the model analysis.

It is suggested that the present AI model can further be developed in order to improve the accuracy of prediction.
Evaluation of horizontal lip position using different soft tissue analysis in Shimla population - A cephalometric study
Authors: Dogra Vaneet , Negi KS , Chainta Dimple , Negi Nishant
Published: December 2023

: 1. To study the horizontal lip position in Dentally and Dentoskeletally normal subjects of Shimla adult population using different soft tissue analysis. 2. To study the sexual dimorphism in horizontal lip position of Shimla adult population. 3. To study the differences of horizontal lip position among Dentally and Dentoskeletally normal subjects of Shimla adult population. 4. To compare the horizontal lip position of Dentoskeletally normal subjects of Shimla adult population with established norms. 5. To assess the most consistent esthetic reference line.

Pre-treatment lateral cephalograms of 100 subjects aged between 18-25 years were taken, who visited the Department of Orthodontics and Dentofacial Orthopaedics Shimla, Himachal Pradesh for their orthodontic consultation for the study.

In Shimla adult population retrusive upper lip in relation to Steiner’s S1 line, Ricketts’ E line and retrusive lower lip in relation to Steiner’s S1 line, Ricketts’ E line, Sushner’s S2 line was found. The norms for upper and lower lip position in relation to Burstone’s B line in Shimla adult population coincide with the established Burstone’s norms. Holdaway’s established norms for lower lip can also be applied to Shimla adult population.

Shimla adult population has different cephalometric norms for horizontal lip position in relation to Steiner’s and Ricketts’ line whereas same established norms of Burstone and Holdaway can be applied to Shimla adult population.
Invisible Orthodontics: Ceramic appliance vs Lingual appliance -A patient perception survey
Authors: Geojan Don G , Misra Vaibhav , Joshi Divya , Vishnupriya TR
Published: December 2023

The aim of the study was to analyse variations in patients’ perception on oral health, aesthetic acceptance, pain perceptions and comfort levels in patients who has undergone/undergoing orthodontic treatment by means of two types of invisible orthodontic appliances: fixed lingual metal brackets and fixed buccal aesthetic/ceramic brackets.

A comparative survey to assess the patient perception after their initial levelling alignment phase was created via Google form and sent to 25 ceramic labially treated and 25 lingually treated patient.

Comfort level, pain perception, speech impediment ,quality of life in patients was significantly better in Ceramic brackets as compared to lingual (p=0.001),Aesthetic perception was significantly higher impact on ceramic (p=0.001) as 72% reported no impact on aesthetics with lingual brackets as compared to 4% in the ceramic brackets. Oral hygiene maintenance: The difference on impact of Oral hygiene maintenance was statistically non- significant between ceramic brackets and lingual brackets (p=0.238).Difficulty while having food was statistically non- significantly between ceramic brackets and lingual brackets.(p=0.448).

Patients prefer lingual treatment cause of their esthetic nature and their expectations are higher with lingual treatment which itself is not favorable from a clinicians perspective and it is worth noting that speech disturbances may lead to greater social embarrassment than more or less invisible ceramic brackets.
Impact of maxillary incisor trauma on child psychology in patients with Class II Div 1 malocclusion in urban population of India
Authors: Bhardwaj Ashutosh , Ray Saugat , Thapa Amrit , Prasanna Kumar MP , Kadu Abhijeet , Sharma Parul
Published: December 2023

Traumatic injuries to maxillary incisors can occur at any age, but its prevalence is high among children. Earlier studies also suggested that patients with increased overjet and lip incompetence were more prone to have trauma to maxillary incisors. The effect of Traumatic dental injuries is not only physical damage but also psychological damage as aesthetic issues are involved. Measures of oral-health-related quality of life (OHRQoL) provide essential information when assessing the treatment needs of individuals and populations.

A total of 300 patients with age group 11-14 years with Class II div 1 malocclsion were included in the study. Patients were further subdivider into three group depending upon the severity of maxillary incisal trauma and no trauma group, further to that the psychological evaluation of all the patients were done using short-form of the Child Perceptions Questionnaire to ascertain the impact of oral health conditions (incisal trauma) on their quality-of-life.

Mean functional limitation score was lowest for group 1 and highest with group 3 with 0.46, 0.626 and 4.191.405 respectively. Mean emotional wellbeing score was lowest in group 1 and highest in group 3 with 1.381.14 and 6.101.46 respectively Overall statistically significant differences were found between three groups w.r.t oral symptoms, functional limitation, emotional wellbeing and social wellbeing with p=0.001.

Traumatic dental injury to maxillary incisors is associated with significant impairment of functionality and significant psychological implications with overall CPQ index scoring being highest in patients with more severe maxillary incisor trauma.