bluuebunny/crossref_metadata_2025 huggingface dataset:
The crystal structure of (azido)-κ1
N-6,6′-((cyclohexane-1,2-diylbis(azanylylidene)) bis(methanylylidene))bis(3-bromophenolato-
κ

4

N,N,O,O)-(methanol)-manganese(III)–methanol(1/1), C
22
H
26
Br
2
MnN
5
O
4
Authors: Liu Dian , Ma Xun
Published: March 2021

C22H26Br2MnN5O4, monoclinic, P21/n (no. 14), a = 8.0106(4) Å, b = 14.5925(7) Å, c = 21.0425(11) Å, β = 100.330(2)°, V = 2419.9(2) Å3, Z = 4, R

gt
(F) = 0.0372, wR

ref
(F
2) = 0.0766, T = 296.15 K.
El sistema de crédito digital para microempresarios en Colombia
Authors: Muñoz G. Lenin A.
Published: March 2021

Se presenta a continuación el Proyecto Aplicado Empresarial denominado ABI – Microcréditos. Emprendimiento en el sector fintech colombiano, que tiene como base la economía colaborativa y que busca constituirse en una estrategia sostenible contra los sistemas de crédito informal y como solución a las necesidades y requerimientos de crédito para la inversión en capital de trabajo de microempresarios; así como un esquema seguro y rentable de apoyo al desarrollo empresarial con base en un gran componente tecnológico y social. Para el presente proyecto se empleó como principal metodología de diseño, modelación y descubrimiento de la solución el Design Thinking, igualmente se recurrió a herramientas como el Value Proposition Canvas para depurar la estrategia de valor y el Buyer Persona para definir el arquetipo de lo que se consideraría como cliente del servicio. A partir de la implementación de estas metodologías y del proceso de empatizar con el problema, el usuario y la competencia, se configuró la solución ABI – Microcréditos. Para terminar se modelaron los principales supuestos del mercado y el impacto de estos sobre el comportamiento financiero del negocio, identificando los principales factores de sensibilidad de la situación financiera y el flujo de caja esperado del proyecto.
КЛЮЧОВІ ТЕНДЕНЦІЇ РОЗВИТКУ СВІТОВОЇ ЕКОНОМІКИ: НОВІ ВИКЛИКИ ТА ПЕРСПЕКТИВИ
Authors: Амоша Олександр , Підоричева Ірина , Землянкін Анатолій
Published: March 2021

Вступ. Глобалізація 4.0 і технологічні інновації, що лежать в її основі, переводять світ до нової ери розвитку – кіберфізичних систем і талантів – ери, яка за масштабами, швидкістю та глибиною змін не має історичного прецеденту.
Проблематика. Останні хвилі глобалізації та промислової революції несуть безпрецедентні виклики та перспективи розвитку, з якими мають бути обізнані країни, регіони, компанії та люди для адекватного реагування та вироблення релевантних рішень.
Мета. Визначення та аналіз ключових тенденцій розвитку світової економіки, пов’язаних з глобалізацією й революційними технологічними трансформаціями в їх єдності та взаємообумовленості, однією з яких є розвиток мережевої економіки як наступної економічної революції, в основу якої покладено довіру, переговори, дипломатію та культуру взаємодопомоги.
Матеріали й методи. Використано методи аналізу й синтезу, порівняльного аналізу та системного підходу. Матеріалами слугували наукові доповіді міжнародних організацій, приватних і публічних компаній, публікації зарубіжних та українських науковців, присвячені зазначеній проблематиці.
Результати. Узагальнено та систематизовано основні риси Глобалізації 4.0 та четвертої промислової революції, які докорінним чином змінюють глобальний економічний, соціальний та геополітичний ландшафт. Здійснено періодизацію хвиль глобалізації, які співставлено з фазами промислових революцій, що дало можливість усебічно проаналізувати процеси глобалізації й технологічного розвитку в їх єдності та взаємообумовленості та на цій основі визначити домінуючі тенденції сучасного світового розвитку.
Висновки. Глобалізація 4.0 і четверта промислова революція трансформують всі сфери діяльності суспільства в усьому світі, а тому мають бути максимально враховані при реалізації стратегічних рішень на всіх рівнях управління – від корпоративного до міжнародного.
THE NEWEST ANALYTICAL TECHNOLOGIES FOR DETERMINING RARE-EARTH ELEMENTS IN GRANITOIDS OF THE UKRAINIAN SHIELD
Authors: Пономаренко Олександр , Самчук Анатолій , Вовк Катерина , Заяць Ольга , Кураєва Ірина
Published: March 2021

Introduction. To date, rare earth elements (REE) are used to manufacture most high-tech goods and are crucial in defense technologies (lasers, radars, and electromagnetic weapons), nuclear engineering, metallurgy, and others. All this determines the relevance of their study to assess the rare earth mineral resource base of Ukraine.
Problem Statement. The determination of REE in rocks and minerals is a fundamental problem in geochemistry and petrology for understanding the processes of rock formation. However, it is a complex analytical task related to the similar chemical properties of these elements, which are caused by the "lanthanide compression effect".
Purpose. The purpose is to develop analytical technologies for determining REE content by the ICP-MS method, to evaluate their content and distribution in granitoids of the Ukrainian Shield.
Materials and Methods. The hybrid method of ICP-MS analysis and microwave decomposition of rocks and minerals has been used to measure the REE content. This technique has been tested and used to estimate the content and distribution of REE in fluorites and rare-metal granitoids of the Rusko-Polyanskyi massif of the Korsun-Novomirgorod pluton of the Ukrainian Shield.
Results. Analytical technologies for determination of REE in granites and minerals have been developed. The method for determining REE in fluorites and granites without their prior concentration in the range from 0.01 to 1000 ppm with a relative standard deviation of 0.01–0.10 has been described. The content of rare earth elements in the Rusko-Polianskyi granites increases (218–797 g/t), the main concentrator of these elements is fluorite (692–26933 g/t REE). An inverse relationship has been observed between the REE content in fluorites and granites.
Conclusions. The developed analytical technologies are the basis for establishing quality assessment criteria and developing principles for the rational use of rare-earth granitoids to create a rare-earth mineral resource base in Ukraine.
The posterior interosseous artery flap versus the adipofascial radial artery perforator flap in reconstruction of firecracker and homemade bomb blast injuries of the hand
Authors: Gupta Madhumita , Jash Prabir Kumar
Published: March 2021

Background: The soft tissues of the radial aspect of the hand are predominantly affected in firecracker and homemade bomb blast injuries. In such cases, regional flap options are quite appealing for defect coverage. We have compared the outcomes of using two pedicled regional forearm flaps in these injuries, the posterior interosseous artery flap (PIAF) and the adipofascial radial artery perforator flap (ARAPF).Methods: 37 patients underwent reconstruction of the hand with PIAF (20 cases) and ARAPF (17 cases) between January 2014 and December 2019. They were compared with regards to patient demographics, reconstruction techniques, short-term and long-term functional and aesthetic outcomes using the disabilities of the arm, shoulder and hand (DASH) score and the subjective satisfaction score (SSS).Results: All our flaps survived without any major complications affecting long-term outcome. We found no statistically significant difference between the two flaps in terms of patient demographics, flap paddle size, duration of hospital stay, DASH score and SSS for recipient site. However, significant difference was noted in the duration of surgery, method of donor site closure and SSS for the donor site.Conclusions: Both the PIAF and ARAPF can be considered in cases of soft tissue defects of the hand from firecracker or bomb blast injuries. Both preserve the major arteries of the hand while still having reliable vascular pedicle.
Conceptualization of Smart System Based on RFID Technologies for Controlling Vehicle Speed
Authors: Asfoura Evan , Abdel-Haq Mohammed Samir , Kassem Gamal
Published: March 2021

The Internet of things and its (IoT) application become more and more effective in various fields of our life. It provides many tangible and intangible advantages. The success of (IoT) Applications required many complimentary dimensions like the enhancements of needed technologies, developing appropriate business models in addition to the security issues. Radio frequency identification (RFID) is one of the widely used technology that belong to IoT family. This paper will introduce a concept model which is performed in Saudi Arabia, and it can be applied in another country as well. Country’s specific requirements regarding legal issues and the use of IoT applications and technologies are taken into consideration, too. This idea is about Smart streets where reader for speed data is used from RFID chip placed in vehicles in order to control the speeds instead of the widely used camera system to increase the safety.
Avguštin Stegenšek (1875–1920): ob stoletnici smrti
Authors: Stavbar Vlasta , Ciglenečki Marjeta ,   University of Maribor Library,   University of Maribor, Faculty of Arts
Published: March 2021

At least three reasons support the presentation of dr. Augustina Stegenška in this brochure or exhibition catalogue. This is a portrait of a young educated and talented art historian who worked in Maribor, a dedicated librarian of the Historical Society for Slovenian Styria, for whom the collection of archival data was a real challenge, and accurate recording led to many research discussions and contributions. The University Library of Maribor keeps a part of Stegenšek's written legacy, which it strives to digitize and in this way make it accessible. The third reason is in cooperation with art history students at the Faculty of Arts, the University of Maribor, with whom the library under the mentorship of Assoc. prof. dr. Marjeta Ciglenečki has been participating in many projects or exhibitions for many years. This time the collaboration was marked by the centenary of Stegenšek's death with a display of his extensive cultural and historical oeuvre. Selected interpretations of Stegenšek's art history articles or books contributed by students of the Faculty of Arts of the University of Maribor are an interesting starting point for further research in this field.
Superabsorbent Polymers (SAPs) Hydrogel: Water Saving Technology for Increasing Agriculture Productivity in Drought Prone Areas: A Review
Authors: Ashraf A. Mohammed , Ragavan T. , Begam S. Naziya
Published: March 2021

To improve the soil moisture availability, by reducing the evaporation losses and retaining the moisture in effective rooting zone. The soil application of superabsorbent polymers (SAPs) is found to be the promising methodology in drought prone areas. However, very limited research work done in Indian conditions on this aspect. One of such successfully developed product is ‘Pusa hydrogel’ which is first indigenous semi-synthetic superabsorbent technology for conserving water and enhancing crop productivity and thereby increases the water use efficiency. It performs its wetting or drying cycles over a longer period of time, maintaining its very high water swelling and releasing capacity against soil pressure. Consequently evaporation, deep water percolation and nutrient leaching can be avoided. Under rainfed condition, crops can better withstand drought condition without moisture stress by using hydrogel. Systematic field studies under arid and semi-arid conditions of India are needed to develop appropriate dose, frequency and method of application of different polymers to various crops and to assess economics of use of different polymers.
Effects of Perennial Intercrops on Oil Palm Agronomic and Yield Traits
Authors: Khomphet Thanet , Eksomtramage Theera , Anothai Jakarat , Popet Pilalak
Published: March 2021

Background: Intercropping is wildly practiced in oil palm plantation in Thailand for a long time. However, there are few studies connected to oil palm intercropping. This study evaluated the effects of perennial intercrops on the agronomic and yield traits of oil palm. Methods: The observation used a completely randomized design with eight treatments including oil palm monocropping, oil palm intercropped with Intsia palembanica, Hopea odorata, Swietenia macrophylla, Ternstroemia wallichiana, Azardirachta excelsa, Magnolia champaca and Mesua ferrea. The height and stem perimeter of intercrops were recorded as were the plant height and diameter, number of male and female inflorescences and sex ratio of the oil palms. Those parameters were observed in October 2019, February and June 2020. Result: Oil palm intercropped with A. excelsa produced the highest number of female inflorescences and oil palm intercropped with M. champaca produced the highest sex ratio in October 2019 and February 2020, however, the differences of those parameters were not found in June 2020. There were no significant differences in the diameter, height, the number of male inflorescences throughout the observation. Among the 7 intercrops, M. champaca and A. excelsa produced the highest growth rate of plant height and stem perimeter, respectively. In conclusion, oil palm can be intercropped with perennial plants. However, more research is needed to determine the long-term effects of intercropping in oil palm.
Virus Vector Relationship of Yellow Mosaic Virus and Whitefly, Bemisia tabaci (Gennadius) in Soybean
Authors: Swathi M. , Gaur Neeta , Singh Kamendra
Published: March 2021

Background: Whitefly is one of the most destructive sucking pest in the tropical and subtropical regions of the world and causing significant crop losses directly by sucking sap from the plants and indirectly through the transmission of viral diseases specifically caused by the genus Begomovirus. The Begomovirus species viz., Mungbean yellow mosaic India virus (MYMIV) and Mungbean yellow mosaic virus (MYMV) are causing yellow mosaic virus disease in soybean, which is transmitted by whiteflies. The disease accounts to 30-70 per cent yield loss and increases up to 80 - 100 per cent during severe incidence. Hence, there is a need for development of integrated pest management strategies against disease and whiteflies, for this the knowledge on virus-vector relationship is required. But, the studies on biological relationship of yellow mosaic virus disease and whitefly in soybean are scarce. At this juncture, considering the importance of disease in soybean, the present investigation was carried out to know the virus -vector relationship of the YMV and whitefly in soybean. Methods: The experiment on virus-vector relationship of yellow mosaic virus and whitefly in soybean was conducted at Department of Entomology, College of Agriculture, G. B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand during 2016-17. The data on number of whiteflies per plant, acquisition and inoculation access feeding period and pre and post starvation period required for effective transmission of virus was recorded. Result: A single viruliferous whitefly was able to transmit virus and ten viruliferous whiteflies per plant were required for cent per cent transmission of virus. The minimum acquisition access and inoculation access feeding periods required for virus transmission was 0.25h (15 min) each; while the 100 per cent virus transmission was recorded with acquisition and inoculation period of 12h, each. The per cent transmission was increased with the increase of acquisition and inoculation periods. The rate of transmission was positively correlated with pre-acquisition starvation period and negatively correlated with post- acquisition starvation period.
Seed Priming: A Low Cost Input for Yield Maximization of Rainfed Chickpea
Authors: Giri M.D. , Jaybhaye C.P. , Kanwade D.G.
Published: March 2021

Background: Moisture availability is the major abiotic limitation in rainfed areas of the country. Reduced germination, weak seedlings and poor plant population are the major causes of low productivity of chickpea in rain fed area. Inadequate soil moisture has adverse effect on seedling emergence, germination, vegetative growth as well as reproductive growth and seed yield. Methods: The experiments were conducted at the Agriculture Research Station (Dr. PDKV), Buldana, Maharashtra, India during 2016-17 to 2019-20 (four years). The experiment consisted of 12 treatments of seed priming replicated three times in randomized block design. Result: Based on the results of four years pooled analysis it was observed that seed priming with 0.5 and 1.0% potassium nitrate resulted in higher plant population and recorded higher grain yield of chickpea crop. Seed priming with potassium nitrate for four hours resulted in the higher gross monetary returns, net monetary returns and B:C ratio.
Screening and Biochemical Analysis on Blackgram Genotypes for Resistance against Storage Pest Bruchine [Callosobruchus maculatus (F.)]
Authors: Ragul S. , Manivannan N. , Iyanar K. , Ganapathy N. , Karthikeyan G.
Published: March 2021

Background: Blackgram [Vigna mungo (L.) Hepper] is a rich source of protein. It is one of the major crops essentially involved in daily human diets. However, storage pest bruchine [Callosobruchus maculatus (F.)] is a major production constraint for legumes. A research was formulated to assess the bruchine resistance in 20 blackgram genotypes along with the biochemical analysis to find out the active biochemical components responsible for the resistance activity. Methods: The experiment was carried out during August- October, 2019 at Entomology Laboratory, National Pulses Research Center, Vamban, India. The experimental material comprised of 20 blackgram genotypes which were screened for bruchine resistance. Further, confirmatory trial was conducted with selected resistant entries and highly susceptible entries during October- December, 2019. Both experiments were carried out in completely randomized design and replicated three times. GC-MS analysis on the resistant and susceptible entries were performed to ascertain the active biochemical components conferring resistance. Result: Among the genotypes, TU 68 had comparatively late developmental time (days), less number of adult emergence, higher mean developmental period (days), less susceptibility index, less seed damage (%) and less seed weight loss (%). Genotype TU 68 was found to be resistant in the confirmatory trial also. Less number of adult emergence and higher mean developmental period indicated the delayed developmental period which is a mechanism of bruchine resistance. GC-MS analysis on resistant (TU 68) and susceptible (MDU 1) genotypes indicated the presence of active biochemical compounds with insectifuge activity in TU 68. Hence, TU 68 could be utilized in the hybridization programmeas donor for bruchine resistance.
Diversity of Insect Fauna Associated with Summer and Monsoon Cowpea [Vigna unguiculata (L.) Walp.]
Authors: Chhangani Gaurang , Mahla M.K. , Swaminathan R. , Jain H.K. , Ahir K.C. , Sharma Kuldeep
Published: March 2021

Background: Cowpea [Vigna unguiculata (L.) Walp.], is one of an important pulse grown throughout the world. The cowpea crop helps in fixation of atmospheric nitrogen; besides, it supports the natural enemies’ population. The study on diversity of pestiferous insect associated with cowpea crop help to understand the population dynamics of these pests depending on location and seasons. These diversity studies are useful to formulate management practices which are area specific. Methods: An extensive survey was conducted at different locations (Udaipur, Bhilwara, Banswara, Chittorgarh and Pratapgarh) of southern Rajasthan during summer (Zaid) and monsoon (Kharif) seasons of 2019 and 2020. The randomly selected plants were observed for pestiferous insect population to calculate different diversity indices. Result: The insect pest complex of cowpea categorized into 5 orders viz., Hemiptera, Thysanoptera, Coleoptera, Diptera and Lepidoptera comprising 14 families. The pestiferous fauna includes population of flea beetle, jassids, whiteflies, sap sucking bugs, leaf miner, thrips, aphids, spotted pod borer and lycaenid caterpillar. During the study, it was found that overall species richness was more during the monsoon season as compared to that during the summer. The relative diversity of aphids was the maximum on account of the clumped distribution and exponential growth. In 2019, the maximum diversity was recorded in Banswara (Simpson index= 6.49 and Shannon index= 2.04) during monsoon; whereas, in 2020, the maximum diversity was recorded in Bhilwara (Simpson index= 4.03 and Shannon index= 1.81) during summer.
¿Historiar es narrar?
Authors: Solà Gussinyer Pere
Published: March 2021

El autor del artículo reflexiona sobre su conversión del resultado de su investigación sobre la vida, el ideario y la obra de un pedagogo catalán de referencia internacional y de trágico final en una propuesta narrativa de ficción. Así, saca partido a las lecciones de una experiencia vital durante el severo confinamiento en una urbe como Barcelona (pero que podría ser cualquier conurbación del ancho mundo) por la pandemia, para mostrarnos hasta qué punto la “verdad histórica” y el “sentido profundo” de un pasado que nos interpela pueden ser potenciados por la narrativa de ficción, más allá de la hojarasca teórica y el andamiaje documental de la producción académica ordinaria.
Production, Properties and Swelling of Copper-Pectic Gel Particles in an Artificial Gastroenteric Environment
Authors: Shubakov Anatoly , Mikhailova Elena
Published: March 2021

The purpose of the this research was to obtain and study the properties of copper-pectic gel particles (CuPGPs) obtained from aqueous solutions of apple pectin (AP) in the concentration range of 1%-5% in the presence of Cu2+ ions. Methods and Results: We used commercial AP AU701 (Herbstreith & Fox KG, Germany). CuPGPs were obtained from aqueous solutions of AP (1%, 3%, 5%) in the presence of Cu2+ ions (1%-10%) by the method of ionotropic gelation, The diameter and density of the CuPGPs were determined. Dry CuPGPs formed from 5% AP with all tested concentrations of copper ions have the largest diameter (0.96-1.15mm), and gel particles formed on the basis of 1% AP have the smallest diameter (0.42-0.74mm). CuPGPs formed from 5% AP have the highest density (1.43-1.65 mg/mm3), and CuPGPs formed on the basis of 1% AP have the lowest density (0.65-0.92 mg/mm3). Gel particles obtained from 1% AP swelled in simulated gastric fluid (SGF) by 161% and then completely degraded immediately upon entering in simulated intestinal fluid (SIF). CuPGPs obtained from 3% AP swelled by 166% in simulated gastric fluid (SGF) and 148% in SIF, and completely degraded in SIF after 2.5 hours of incubation in it. Gel particles obtained from 5% AP in the presence of 10% Cu2+ swelled most strongly – by 173% in SGF and by 208% in SIF. And then, they degraded after 8 hours of incubation in simulated colonic fluid (SCF).
Diffuse Peripheral Pulmonary Stenosis as a Cause of Pulmonary Arterial Hypertension Case Report and Literature Review
Authors: Rincon Imelda , Garcia-Amaya Vladimir , Blanco-Velazco Daniel , Yañez-Gutierrez Lucelli , Salazar-Lizarraga David , Garcia-Davalos Israel , German-Arroyo Cristopher , Marquez-Gonzalez Horacio , Lopez-Gallegos Diana , Santiago-Hernandez Jaime
Published: March 2021

Introduction: Peripheral pulmonary arterial stenosis is poorly recognized in the adult population that it can cause pulmonary hypertension, but it is likely that it is misdiagnosed as idiopathic pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension. Case description: 16-year-old female, in functional class II, grade II systolic murmur pulmonary focus, saturation 96%. Chest tomography: left peribronchovascular consolidation. Catheterization: diffuse peripheral pulmonary stenosis, perfusion defect in the left lobe vasculature, probable thrombosis vs atresia, PMAP 78mmHg. Preserved biventricular systodiastolic function. Perfusion lung scan: pulmonary thromboembolism. Methodology: The Boolean method was used to search for MESH terms "segmental arteries" "pulmonary" [and] "stenosis" in the database with repositories of indexed arbitrary scientific evidence (PubMed) and not indexed (ScholarGoogle). Discussion Patients with this disease usually have systemic pressures of the right ventricle secondary to obstruction in the lobar, segmental, and subsegmental branches. Small segmental artery stenting, particularly in patients with congenital diffuse peripheral pulmonary stenosis, has been less successful. Conclusions: In recent years, peripheral pulmonary artery surgery has been associated with low mortality and a reduction in the RV / Ao pressure ratio of almost 50%. The current treatment of these patients remains somewhat controversial and poorly documented since there are places where they cannot be approached surgically.
Biomechanical Energy Analysis and Functional Evaluation of a Lower Limb Energy Harvesting and Transmission Exoskeleton
Authors: Zhou Xin , Tang Yunqi , Wang Zhe , Zhang Tong , Liu Xiaoli
Published: March 2021

Background: Human beings are constantly adjusting their strategies to adapt to the new environment along with the rapid evolution and development. Scientists have made great effort to collect the energy consumed by walking and provide it as energy input to join the energy circulation system. It can be utilized to rehabilitation training, walking assistance and energy compensation of patients with mild hemiplegia. Methods: Based on the clinical medical viewpoint of healthy side teaching the affected side, through harvesting the energy of the healthy side of the lower limb, release it when the affected side works, to realize the movement assistance independently. Therefore, this paper describes an energy harvesting and transmission exoskeleton (EHTE) to achieve the biomechanical energy harvest, management, and transmission. The human experiment and function evaluation was carried out to explore the influence mechanism on the main muscles of human lower limbs. The data acquired by the sEMG experiment, and sEMG signals were recorded. Results: The result shows that EHTE can reduce the strength and activity of some muscles and achieve ipsilateral and contralateral lower limb assistance. The sEMG signal of muscle changes considerably during walking with EHTE, which indicates that muscle contraction has enhanced. Conclusions: It suggested that the body adjusts physiological changes automatically to adapt to energy transmission during walking. EHTE provides a potential solution to enhance exercise ability, prolong the joint life, delay the development of disease and improve the quality of life.
Development and Usability Evaluation of an Application for Patients With Glaucoma
Authors: Valente Paula Soares de Mattos Carneiro , Carneiro Carolina Lyra Barreira , Aguiar Ridson Guilherme Parente de , Júnior Francisco Emanoel Albuquerque de Souza , Maciel Alex Andrade , Marçal Edgar , Neto José de Paula Barbosa , Ribeiro Joao Crispim
Published: March 2021

IntroductionGlaucoma is a progressive optic neuropathy that requires continuous monitoring. The purpose of the study was to develop and evaluate the usability of a mobile application, for iOS and Android platforms, containing functionalities to improve patients’ knowledge about glaucoma and facilitate their treatment. MethodsThe application was developed by a multidisciplinary team using an adapted version of a co-design methodology. Thirty-six volunteers were selected, among patients and patients' relatives, from the Instituto Cearense de Oftalmologia, chosen by rational choice sampling, to answer the System Usability Scale after having prior orientation. The results extracted from the questionnaire were analyzed quantitatively. After grouping by age, a proportions test (z-test) was performed. ResultsIt was possible to develop an application for mobile devices named “GlaucoCheck”. Of the 36 interviewees, the average age was 51 (22-69) years old, 56% were women, and 64% had a university degree. The average APP score for usability in the SUS questionnaire was 75.6 (95% CI 74.1-77.2). DiscussionThere was an appropriate acceptance of patients to the “GlaucoCheck”, as it was considered easy to handle, exhibiting interactive and uncomplicated layout. It was possible to develop an application and to register a positive acceptance by the users, encompassing functions that permits better adherence to treatments and additional knowledge about glaucoma.
Removal of Migrated Esophageal Stents in the Stomach Under the Guidance of Fluoroscopy: a Single-center Retrospective Study
Authors: Ren Kewei , Liu Haitao , Zhou Zihe , Li Yahua , Lu Huibin , Han Xinwei , Ren Jianzhuang
Published: March 2021

Background: Migrated esophageal self-expandable metal stents (SEMSs) increase the risk of bowel obstruction or perforation. The endoscopic removal of migrated stents is extremely difficult due to the inability to observe the distal end of the stent during retrieval. Here, we report our experience removing migrated esophageal stents in the stomach under the guidance of fluoroscopy.Material and methods: The clinical data of patients with esophageal stents that migrated to the stomach between January 2016 and March 2020 were analyzed retrospectively. A total of 27 patients (9 females and 18 males) were included in this study. Three methods of retrieval were considered: direct removal via a fixed string, direct removal via a retrieval hook, and retrieval via guide wire and gooseneck snare.Results: A total of 28 migrated esophageal stents in the stomachs of 27 patients were successfully removed under the guidance of fluoroscopy by the three methods mentioned above: 10 cases of direct removal via a fixed string, 14 cases of direct removal via a retrieval hook, and 3 cases of retrieval via a guide wire. The stent removal time was 18 (7-60) minutes. During the operation, one patient had a small amount of esophageal bleeding that was cured after symptomatic treatment, and one patient had a residual fracture stent wire that was removed under endoscopy.Conclusion: The removal of migrated esophageal stents in the stomach under the guidance of fluoroscopy is a feasible and safe procedure.
Surgical Treatment of Carpal Tunnel Syndrome and Lymphedema in Advanced-Stage Upper Extremity Lymphedema
Authors: Kim Soo-Byn , Moon Kyung-Chul
Published: March 2021

Background Recent advances in supermicrosurgery have evolved to treat lymphedema surgically. For patients with carpal tunnel syndrome (CTS) and advanced-stage lymphedema, lymphovenous anastomosis (LVA) may effectively improve lymphedema after carpal tunnel release in patients with CTS and advanced stage lymphedema. However, no studies have reported simultaneous carpal tunnel release and LVA surgeries for patients with CTS and advanced-stage lymphedema.Case Presentation A 60-year-old female with carpal tunnel syndrome and International Society of Lymphology late stage 2 right upper extremity lymphedema following right mastectomy and axillary lymph node dissection and adjuvant chemoradiotherapy for treating breast cancer was admitted to our lymphedema clinic. She developed carpal tunnel syndrome four years after breast cancer surgery. She underwent release of the transverse carpal ligament, followed by four lymphovenous anastomoses at the wrist, forearm, and antecubital area. After two simultaneous surgeries, she had less neuropathic pain and volume reduction in her hand.Conclusion The authors recommend simultaneous LVA and release of the transverse carpal ligament as the first treatment option for patients with advanced-stage lymphedema and concurrent CTS.
The Role of ERBB4 Mutations in the Prognosis of Advanced Non-small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors
Authors: Hu Xilin , Wen Ruran , Xu Hanlin , Jiao Wenjie , Tian Kaihua
Published: March 2021

Introduction: Recently, immune checkpoint inhibitors (ICIs) has been reported to achieved convincing clinical benefits and significantly prolonged the overall survival (OS) of advanced non-small cell lung cancer (NSCLC) patients. Sensitivity to immunotherapy was related to several biomarkers, such as PD-L1 expression, TMB level, MSI-H and MMR. However, novel biomarkers for the prognosis to ICIs treatment need to be further investigated, and it is an urgent demand to establish a systematic hazard model to assess the efficacy of ICIs therapy for advanced NSCLC patients.Methods: In this study, gene mutation and clinical data of NSCLC patients was obtained from the TCGA database. Then, we analyzed the detailed clinical information and mutational data of two advanced NSCLC cohorts received ICIs treatment from the cBioPortal for Cancer Genomics. The Kaplan-Meier plot method was used to perform survival analyses, selected variables were used to develop a systematic nomogram. The prognostic significance of ERBB4 in pan-cancer was analyzed by another cohort from cBioPortal for Cancer Genomics.Results: Mutation frequencies of TP53 and ERBB4 was 54% and 8% in NSCLC, respectively. Mutual exclusive analysis in cBioPortal indicated that ERBB4 does show co-occurencing mutations with TP53. Patients harbored ERBB4 mutations were confirmed to have a better prognosis for ICIs treatment, compared to ERBB4 wild type (PFS: p=0.0360; OS: p=0.0378) and only TP53 mutations (OS: p=0.021). The mutation status of ERBB4 and TP53 are tightly linked to DCB for ICIs treatment, PD-L1 expression, TMB value and TIICs. Finally, a novel nomogram was built to evaluate the efficacy of ICIs therapy.Conclusion: ERBB4 mutations could serve as a predicting biomarker for prognosis of ICIs treatment. The systematic nomogram was proven to have a great potential to evaluate the efficacy of ICIs therapy for advanced NSCLC patients.
Beyond Hemoglobin A1c: A Videographic Analysis of Conversations About Quality of Life and Treatment Burden During Clinical Encounters for Diabetes Care
Authors: Haider Shanzay , Kawkgi Omar El , Clark Jennifer , Breslin Maggie , Boehmer Kasey R. , Montori Victor , Lipska Kasia J.
Published: March 2021

Purpose: Diabetes care has largely focused on reducing the risk of complications by achieving hemoglobin A1c (HbA1c) targets; yet, whole-person care may be more effective and desirable. We sought to determine the nature of discussions about quality of life, burden of treatment, hypoglycemia, sexual function, and social support during diabetes-focused clinical encounters.Methods: We analyzed 41 previously recorded clinical encounters with patients with type 2 diabetes from the control arms of practice-based trials of shared decision making. Two coders evaluated videos for discussions about aspects of life with diabetes: quality of life, burden of treatment, hypoglycemia, sexual function, and social supports. When an aspect was raised, coders evaluated the nature of the conversation, clinician responses, and time spent on discussing the aspect. Results: Median length of the encounter was 15 minutes, 6 seconds (IQR: 11:16 – 20:23 minutes). Thirty five of 41 encounters (85.4%), included some discussion of quality of life (58.5%), burden of treatment (51.2%), social support (2.4%), or hypoglycemia (9.8%). Sexual function was not discussed. On average, 4.5% (1.4%-5.5%) of the encounter time involved conversations about HbA1c whereas 15.0% (0%-25%) of the encounter was spent on some aspect of quality of life, burden of treatment, social support, or hypoglycemia. If a topic related to quality of life was raised, clinicians most often responded by acknowledging patient’s concern without providing a solution (45.8%). Conclusions: A significant part of the patient-clinician encounter involves discussion of quality of life and burden of treatment, but clinicians rarely address these issues by providing solutions.
Pattern, Causes, and Treatment Outcome of Neonates Admitted at Hiwot Fana Specialized University Hospital, Eastern Ethiopia.
Authors: Eyebru Addis , Getachew Tamirat , Debela Adera , Degefa Meron , Kebede Daniel , Dheresa Merga
Published: March 2021

Background: Neonatal period is the most the vulnerable time for survival of newborns. In Ethiopia, neonatal death remains increasing and requires extraordinary efforts and a novel intervention to reduced neonatal death as those deaths continue to occur in even hospital settings where there are the best neonatal care services. Despite many efforts done to improve the outcome of neonates admitted to hospitals; neonates continue dying in those settings. The causes of neonatal death in Ethiopia varies from place to place. So, identifying the causes of death in the study area is very important for prevention and treatment. The study aimed to assess the causes and factors associated with treatment outcomes. Methods: Institution-based cross-sectional study design was conducted among 707 randomly selected neonates from March 1 to 31, 2020. Data were extracted from medical records using a checklist adapted from WHO and neonatal registration book. The data were inserted into Epi-data version 3.1 and then exported into SPSS window version 22 for analysis. Bivariate and multivariate analyses were done to identify the association between independent variables and the outcome variable. Results: From 698 admitted neonates during 2 years period, 594 of them were improved and 104 of them were died. The proportion of neonatal death was 14.9% (95% CI:12.3,17.9). Neonatal sepsis, low birth weight and prematurity were the leading cause of neonatal death. Residency [ AOR=2.30, 95%CI: (1.3, 4.12)], low birth weight [AOR=2.52, 95%CI: (1.24,5.13))], respiratory distress syndrome [AOR =2.86, 95%CI:(1.11.7.35)], neonatal sepsis [AOR= 2.48, 95%CI: (1.40, 4.38)], and Neonates treated with phototherapy and oxygen [ AOR=0.22, 95%CI:(0.088,0.54)], [AOR= 0.47,95%CI:(0.22,0.99)] were factors associated with poor treatment outcome.Conclusion: The causes of neonatal death were mainly from preventable and treatable causes like neonatal sepsis, low birth weight, and prematurity in the study setting. Residency, low birth weight, respiratory distress syndrome, having neonatal sepsis, treatment with phototherapy, and treatment with oxygen were independent factors. The concerned bodies should give attention to neonates admitted to intensive care units by strengthening the quality of care given at the unit and strengthening early detection and prevention of neonatal problems during post-partum periods.
Prevalence of oral mucosal lesion in peri-urban area of Lucknow city (Uttar Pradesh)
Authors: Singh Pallavi , Malhotra Shitanshu , Agarwal Neha , Mishra Gaurav , Dubey Himangi
Published: March 2021

Introduction: . The oral mucosa performs essential protective functions that  affect the general health of the patient. Oral lesions can cause discomfort or pain that interferes with mastication, swallowing, and speech. Aim: The aim of this study is to assess the prevalence of oral mucosal lesions in periurban area in the city of Lucknow aged 15 years and above. Settings and Design: A multistage random sampling was done for identifying the study sample. Materials & Methods: In the first stage. all  peri-urban areas of Lucknow city was grouped into four geographical zones. Second stage consisted of random selection of 20 peri-urban areas by lottery method (5 from each zone).  In third stage there was selection of individuals using simple random method. A total of 45 individuals was selected. Thus a total 900 individuals was selected (i.e. 225 from each zone). Results: The prevalence of oral mucosal lesion in the present study was found to be 11.8%.  The percentage of patients suffering from leukoplakia, oral submucous fibrosis  and lichen planus was 51.9%, 20.8% & 11.3% respectively. Conclusion: This survey high-lighted the rampant misuse of variety of harmful substances as well as the high prevalence of oral lesions in the community.
Focal fibrous hyperplasia beneath the tongue – A rare case report
Authors: Razi Mohammed Ahsan , Debnath Surangama , Kirtaniya Bimal  Chandra , Seema Qamar
Published: March 2021

Focal fibrous hyperplasia is a slow growing connective tissue tumor that frequently occurs in different anatomic sites of the oral cavity. The present case report describes the occurrence of this lesion on the ventral surface of the tongue which is hitherto least reported intraoral site, in a 11 year old male patient, which was successfully excised.
Kinetics and design of distillation reactor with ZSM-5@SiC foam catalytic packing for EL synthesis in industrial scale
Authors: Ding Qiuyan , Li Hong , Chen Zihao , Guan Yanan , Li Xingang , Zhang Jinsong , Jiao Yilai , Zou Jing , Gao Xin
Published: March 2021

Distillation reactor is one of the important equipment to improve the
reaction conversion limited by the chemical equilibrium, however, the
design of distillation reactor in industrial scale is still challenging
due to the lack of efficient catalytic packing with corresponding
kinetics. This work developed the novel catalytic packing consists of
the structured ZSM-5@SiC foam catalyst and corrugated sheet, which used
in distillation reactor for synthesis of ethyl levulinate (EL). The
kinetic of structured ZSM-5@SiC foam catalyst was measured and model
regarding the “structure factor” of ZSM-5@SiC catalyst and fluid flow
conditions. Furthermore, the design of distillation reactor in
industrial scale has been performed based on the developed kinetics,
which demonstrated an excellent performance in the designed distillation
reactor (EL yield 37.65% with energy consumption 3695 kJ/kg) are
achieved. X-ray CT characterization revealed that the ZSM-5 coating
thickness has the significantly effects on the kinetics and performances
of distillation reactor.
FEATURES OF INTERPERSONAL INTERACTION OF PSYCHOLOGISTS WITH DIFFERENT LEVELS OF SOCIAL INTELLIGENCE
Authors: Sytnik Svitlana , Chebykin Oleksiy
Published: March 2021

An important aspect of the professional activity of psychologists is the interpersonal interaction, the effectiveness
of which depends on many factors. One of them may be a social intelligence. The study of the relationship between
social intelligence and the characteristics of interpersonal interaction can point at the possibility of improving the professional skills of psychologists, through the activation of their social intelligence, which is related to the level of interpersonal interaction. This interaction is an important component of the professionalism of the psychologist. The purpose
of the article was to study the relationship of particularities of interpersonal interaction of psychologists with different
levels of social intelligence and their individual psychological characteristics. The theoretical and experimental methods
were used in the study. The latter include the following methods: "Assessment of interpersonal interaction"
(Sytnik S. V.); "Study of Social Intelligence" (J. Guilford); "16-PF Personal Questionnaire" (R. Kettell). The relationship of indicators of interpersonal interaction with social intelligence and character traits of individual were presented in
the article. The interpersonal interaction includes such indicators as primary contact, interpersonal communication and
interpersonal relationships. A sufficient level of development of social intelligence is associated with effective interpersonal interaction. The direct connections of indicators of interpersonal interaction with such personality traits as sociability, emotional stability, courage, trust, practicality, calmness are determined. The feedback was also identified with
traits such as hostility, irritability, low tolerance for frustration, shyness, social passivity, cruelty, anxiety, and selfdoubt. It is investigated that a high level of social intelligence is a condition for the development of all stages of interpersonal interaction. The subjects who are capable of interpersonal interaction at a high level have such traits as sociability, trust, balance, courage, emotional stability. Individuals with a low level of interpersonal interaction often show:
emotional instability, social passivity, isolation, hostility, irritability, suspicion. The obtained results are important for
the psychological training of psychologists as representatives of socionomic professions, in order to realize themselves
in professional activities.
HYPERHOMOCYSTEINEMIA AS THE PATHOGENETIC FACTOR IN OBSTETRICAL COMPLICATIONS
Authors: Linnikov Svyatoslav
Published: March 2021

The study of the influence of various levels of the hyperhomocysteinemia with mutation in
methylenetetrahydrofolate reductase (МТНFR) on the system of the hemostasis was carried out. 84 patients were
examined with various obstetrical pathology in the anamnesis. The genetic form of the hyperhomocysteinemia with
various degrees of severity has been revealed in 21 (25%) patients. At the stage of planning of pregnancy and in the I-st
trimester the thrombophilia manifestations were revealed: increasing the activity thrombocytes, the quantity of markers
of thrombophilia D-dimer, ТАТ, F1+2. Thrombophilia augmented with terms of preeclampsia and the degree of
severity of the hyperhomocysteinemia. The offered pathogenetic algorithm of treatment of thrombophilia state of
patients using the low-molecular weight heparin (clexane), a folic acid, vitamin В6, В12 antioxidants has given the
significant positive effect. It is necessary to carry out the studies of the hemostasis on latent thrombophilia and to carry
out, if necessary, the antitromboembolitic therapy to establish the ethiopathogenetics of obstetrical complications. It will
enable to exclude the further perinatal losses.
Protection of Thiophenone in Catfish (Clarias sp.) Larvae When Challenged with Aeromonas hydrophila
Authors: Indriyanti Ana , Julyantoro Pande Gde Sasmita , Wijayanti Ni Putu Putri
Published: March 2021

This research aimed to determine the ability of quorum sensing inhibitor compound thiophenone to protect catfish (Clarias sp.) larvae when challenged with the pathogenic Aeromonas hydrophila. This research was conducted at Fisheries Laboratory, Faculty of Marine Science and Fisheries, Udayana University, from December 2019 to January 2020. The experiment was setting up with four treatments and three replications for each treatment. 10 larvae of catfish were maintained in aquarium 15 cm × 15 cm × 20 cm filled with 1 liter of freshwater and used aeration for oxygen supply. The treatments were treatment A (control), treatment B (addition of A. hydrophila 106 cfu/ml), treatment C (addition of thiophenone 10 µM), and treatment D (addition of A. hydrophila 106 cfu/ml and thiophenone 10 µM). The results showed that the addition of thiophenone 10 µM increased the survival of catfish larvae up to 73% when challenged with A. hydrophila. That was significantly difference (P<0,05) compare to treatment B with survival rate of 43% within 3 days of culture period. Although it was not statistically different (P>0,05), the highest absolute weight and length were found in treatment A of 0,47 g and 0,50 cm, respectively, while the lowest absolute weight and length were found in treatment B about 0,23 g and 0,17 cm, respectively. The water quality such as temperature, pH and DO were still within the range that supported the growth and survival of catfish larvae during this study.