bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcriptome Profiling of Potato (Solanum tuberosum L.) Responses to Root-Knot Nematode (Meloidogyne javanica) Infestation during A Compatible Interaction
Authors: Macharia Teresia N. , Bellieny-Rabelo Daniel , Moleleki Lucy N.
Published: September 2020

Root-knot nematode (RKN) Meloidogyne javanica presents a great challenge to Solanaceae crops, including potato. In this study, we investigated transcriptional responses of potato roots during a compatible interaction with M. javanica. In this respect, differential gene expression of Solanum tuberosum cultivar (cv.) Mondial challenged with M. javanica at 0, 3 and 7 days post-inoculation (dpi) was profiled. In total, 4948 and 4484 genes were detected, respectively, as differentially expressed genes (DEGs) at 3 and 7 dpi. Functional annotation revealed that genes associated with metabolic processes were enriched, suggesting they might have an important role in M. javanica disease development. MapMan analysis revealed down-regulation of genes associated with pathogen perception and signaling suggesting interference with plant immunity system. Notably, delayed activation of pathogenesis-related genes, down-regulation of disease resistance genes, and activation of host antioxidant system contributed to a susceptible response. Nematode infestation suppressed ethylene (ET) and jasmonic acid (JA) signaling pathway hindering JA/ET responsive genes associated with defense. Genes related to cell wall modification were differentially regulated while transport-related genes were up-regulated, facilitating the formation of nematode feeding sites (NFSs). Several families of transcription factors (TFs) were differentially regulated by M. javanica infestation. Suggesting that TFs play an indispensable role in physiological adaptation for successful M. javanica disease development. This genome-wide analysis reveals the molecular regulatory networks in potato roots which are potentially manipulated by M. javanica. Being the first study analyzing transcriptome profiling of M. javanica-diseased potato, it provides unparalleled insight into the mechanism underlying disease development.
Magma Mingling in Kimberlites: Evidence from the Groundmass Cocrystallization of Two Spinel-Group Minerals
Authors: Xu Jingyao , Melgarejo Joan , Li Qiuli , Abat Lisard , Castillo-Oliver Montgarri
Published: September 2020

We present the results of a detailed petrographic study of fresh coherent samples of the Menominee kimberlite sampled at site 73, located in Menominee County, MI, USA. Our objective is to account for its unusual and complex paragenetic sequence. Several generations of olivine, ilmenite, and spinel-group minerals are described. Early olivine and ilmenite are xenocrystic and were replaced or overgrown by primary minerals. Zoned microcrysts of olivine have a xenocrystic core mantled by a first rim in which rutile, geikielite, and spinel s.s. (spinel sensu stricto) cocrystallized. The in situ U–Pb dating of a microcryst of primary rutile yielded 168.9 ± 4.4 Ma, which was interpreted as the age of emplacement. The groundmass consists of olivine, spinel s.s., a magnesian ulvöspinel–ulvöspinel–magnetite (MUM) spinel, calcite, and dolomite. An extremely low activity of Si is suggested by the crystallization of spinel s.s. instead of phlogopite in the groundmass. The presence of djerfisherite microcrysts indicates high activities of Cl and S during the late stages of melt crystallization. The occurrence of two distinct spinel-group minerals (spinel s.s. and qandilite-rich MUM) in the groundmass is interpreted as clear evidence of the mingling of a magnesiocarbonatitic melt with a dominant kimberlitic melt.
Impacts of Endocrine Disruptor di-n-Butyl Phthalate Ester on Microalga Chlorella vulgaris Verified by Approaches of Proteomics and Gene Ontology
Authors: Liao Chien-Sen , Hong Yong-Han , Nishikawa Yoshikazu , Kage-Nakadai Eriko , Chiou Tai-Ying , Wu Chien-Chang
Published: September 2020

Di-n-butyl phthalate (DBP) is an extensively used plasticizer. Most investigations on DBP have been concentrated on its environmental distribution and toxicity to humans. However, information on the effects of plasticizers on algal species is scarce. This study verified the impacts of endocrine disruptor di-n-butyl phthalate ester on microalga Chlorella vulgaris by approaches of proteomics and gene ontology. The algal acute biotoxicity results showed that the 24h-EC50 of DBP for C. vulgaris was 4.95 mg L−1, which caused a decrease in the chlorophyll a content and an increase in the DBP concentration of C. vulgaris. Proteomic analysis led to the identification of 1257 C. vulgaris proteins. Sixty-one more proteins showed increased expression, compared to proteins with decreased expression. This result illustrates that exposure to DBP generally enhances protein expression in C. vulgaris. GO annotation showed that both acetolactate synthase (ALS) and GDP-L-fucose synthase 2 (GER2) decreased more than 1.5-fold after exposure to DBP. These effects could inhibit both the valine biosynthetic process and the nucleotide-sugar metabolic process in C. vulgaris. The results of this study demonstrate that DBP could inhibit growth and cause significant changes to the biosynthesis-relevant proteins in C. vulgaris.
Efficient Synthesis of α-Branched Purine-Based Acyclic Nucleosides: Scopes and Limitations of the Method
Authors: Frydrych Jan , Poštová Slavětínská Lenka , Dračínský Martin , Janeba Zlatko
Published: September 2020

An efficient route to acylated acyclic nucleosides containing a branched hemiaminal ether moiety is reported via three-component alkylation of N-heterocycle (purine nucleobase) with acetal (cyclic or acyclic, variously branched) and anhydride (preferentially acetic anhydride). The procedure employs cheap and easily available acetals, acetic anhydride, and trimethylsilyl trifluoromethanesulfonate (TMSOTf). The multi-component reaction is carried out in acetonitrile at room temperature for 15 min and provides moderate to high yields (up to 88%) of diverse acyclonucleosides branched at the aliphatic side chain. The procedure exhibits a broad substrate scope of N-heterocycles and acetals, and, in the case of purine derivatives, also excellent regioselectivity, giving almost exclusively N-9 isomers.
Evaluation of the Perceptual Interactions among Aldehydes in a Cheddar Cheese Matrix According to Odor Threshold and Aroma Intensity
Authors: Chen Chen , Zhou Wenya , Yu Haiyan , Yuan Jiajie , Tian Huaixiang
Published: September 2020

To evaluate the contributions of 3-methylbutanal, 2-methylbutanal, 2-methylpropanal, and benzaldehyde in cheddar cheese models, the threshold values, optimal concentration ranges, and perceptual actions of these compounds were determined at various concentrations. The thresholds for 3-methylbutanal, 2-methylbutanal, 2-methylpropanal, and benzaldehyde in the cheese matrix were 150.31, 175.39, 150.66, and 500.21 μg/kg, respectively, which were significantly higher than the corresponding values in water. The optimal concentration ranges of these aldehydes were determined as 150–300, 175–325, 150–350, and 500–1500 μg/kg, respectively. Based on the results of the threshold method and Feller’s model, five binary mixtures were found to have synergistic effects, and only the pair of 2-methylpropanal and benzaldehyde was determined to have a masking effect. In addition, the synergistic olfactory effects between the four ternary mixtures and the quaternary mixture of these aldehydes were also assesSsed using Feller’s model. In a σ-τ plot analysis, synergism was usually observed when these odor pairs were at their threshold levels. In summary, the results suggested that perceptual interactions among these aldehydes exist in a cheese model variably with different concentrations and threshold ratios. This study will be helpful to a further understanding of the nutty aroma and improving the aroma quality of cheddar cheese.
Investigating the Aging Effects of Biochar on Soil C and Si Dissolution and the Interactive Impact on Copper Immobilization
Authors: Jiang Shaojun , Wu Jiachen , Duan Lianxin , Cheng Sheng , Huang Jian , Chen Tao
Published: September 2020

Aging tests were used to investigate the long-term effects of BC on the immobilization of Cu, and the soil silicon dissolution of three types soils (black soil, (BS), vegetable garden soil (VS) and red soil (RS)). Litchi branch biochars (BC) at 10% (w/w) were incubated with three Cu (400 mg/kg) contaminated soils. The effect on soil properties of pH, soil organic carbon (SOC), dissolved organic carbon (DOC) and available silicon content were investigated, along with the speciation distribution of Cu. The results indicated that SOC, DOC, and available silicon content (except, BC300) increased with the application of BCs. On the other hand, the DTPA (diethylenetriaminepentaacetic acid) extractable Cu content in BS, VS and RS soils were reduced by 4–12%, 18–25%, and 12–19%, respectively. The Cu availability in all soils first increased, and then decreased during the aging process. The sum of the other four fractions, including the carbonate fraction and the inert component increased by 4–4.5% (BS), 1.4–2.1% (VS), and 0.5–1% (RS) respectively, over the long-term process. Moreover, during the whole aging process, the soil properties (such as pH, SOC, DOC and available silicon content) were almost stable. This study demonstrates that BCs, especially those produced at a higher temperature, are superior to those been produced at 300 °C in immobilizing Cu and releasing available silicon in soils. However, the remediation efficiencies were restricted by the soil type contamination status and remediation time.
Downregulation of Inflammatory Cytokine Release from IL-1β and LPS-Stimulated PBMC Orchestrated by ST2825, a MyD88 Dimerisation Inhibitor
Authors: Ramírez-Pérez Sergio , Hernández-Palma Luis Alexis , Oregon-Romero Edith , Anaya-Macías Brian Uriel , García-Arellano Samuel , González-Estevez Guillermo , Muñoz-Valle José Francisco
Published: September 2020

The inflammatory process implicates homeostasis disruption and increased production of inflammatory mediators. Myeloid differentiation primary response 88 (MyD88) is an essential protein recruited after lipopolysaccharide (LPS) and interleukin (IL)-1β stimulation, a process that converges in nuclear factor kappa B (NF-κB) activation, as well as a transcription of several genes of both pro- and anti-inflammatory cytokines. The inhibition of MyD88 has shown efficacy by decrease inflammatory response, and has demonstrated potential application as a therapeutic target in chronic diseases. In this study, we investigate the effect of MyD88 dimerisation inhibitor ST2825 on cytokine production from rhIL-1β and LPS-stimulated peripheral blood mononuclear cells (PBMC) from healthy blood donors (HBD). ST2825 significantly downregulates the production of IFN-γ, IL-6, IL-12, IL-2, IL-15, IL-7, VEGF, IL-1Ra, IL-4, IL-5, IL-13 and IL-9 (p < 0.05) in LPS-stimulated PBMC. Moreover, ST2825 had a relatively low impact on IL-1β signalling pathway inhibition, showing that only a few specific cytokines, such as IFN-γ and IL-1Ra, are inhibited in rhIL-1β-stimulated PBMC (p < 0.01). In conclusion, MyD88 dimerisation inhibitor ST2825 showed high efficacy by inhibiting pro- and anti-inflammatory cytokine production in LPS-stimulated PBMC. Moreover, although rhIL-1β induced a sustained cytokine production (p < 0.05), ST2825 did not show a significant effect in the secretion of neither pro- nor anti-inflammatory cytokines in rhIL-1β-stimulated PBMC.
Boronic Acids and Their Derivatives in Medicinal Chemistry: Synthesis and Biological Applications
Authors: Silva Mariana Pereira , Saraiva Lucília , Pinto Madalena , Sousa Maria Emília
Published: September 2020

Boron containing compounds have not been widely studied in Medicinal Chemistry, mainly due to the idea that this group could confer some toxicity. Nowadays, this concept has been demystified and, especially after the discovery of the drug bortezomib, the interest for these compounds, mainly boronic acids, has been growing. In this review, several activities of boronic acids, such as anticancer, antibacterial, antiviral activity, and even their application as sensors and delivery systems are addressed. The synthetic processes used to obtain these active compounds are also referred. Noteworthy, the molecular modification by the introduction of boronic acid group to bioactive molecules has shown to modify selectivity, physicochemical, and pharmacokinetic characteristics, with the improvement of the already existing activities. Besides, the preparation of compounds with this chemical group is relatively simple and well known. Taking into consideration these findings, this review reinforces the relevance of extending the studies with boronic acids in Medicinal Chemistry, in order to obtain new promising drugs shortly.
The Effect of Cultivation Method of Strawberry (Fragaria x ananassa Duch.) cv. Honeoye on Structure and Degradation Dynamics of Pectin during Cold Storage
Authors: Drobek Magdalena , Frąc Magdalena , Zdunek Artur , Cybulska Justyna
Published: September 2020

The high quality and long shelf life of strawberry fruit are largely dependent on the cultivation method. The goal of this experiment was to study the effect of different cultivation methods on molecular structure and rheological properties of pectin extracted from strawberry quality parameters during cold storage. Three methods of cultivation of strawberry cv. Honeoye were tested: organic cultivation on raised beds, organic cultivation with the flat-planted method and conventional cultivation with the flat-planted method. The nanostructure of pectin (AFM), its chemical structure (FT-IR) and rheological properties were studied. The fruits were also tested by size, dry matter, firmness, acidity and the content of soluble solids, anthocyanin, phenolics, vitamin C and galacturonic acid. Pectin isolated from organic strawberries was more rapidly degraded than conventional strawberry pectin, which limits the possibilities for their processing and use as gelling or stabilizing agents at 20 °C. The differences in fruit quality were particularly noticeable with respect to the anthocyanin content, which was significantly higher for organic strawberry. The organic fruit also had better sensory properties because of its lower acidity and higher soluble solid content (SSC). These and other results from this experiment showed that strawberries produced by organic farming methods had better biochemical properties compared to conventional fruit; however, pectin transformation undergone faster limits their further technological applications.
Attempts to Target Staphylococcus aureus Induced Osteomyelitis Bone Lesions in a Juvenile Pig Model by Using Radiotracers
Authors: Afzelius Pia , Alstrup Aage , Nielsen Ole , Nielsen Karin , Jensen Svend
Published: September 2020

Background [18F]FDG Positron Emission Tomography cannot differentiate between sterile inflammation and infection. Therefore, we, aimed to develop more specific radiotracers fitted for differentiation between sterile and septic infection to improve the diagnostic accuracy. Consequently, the clinicians can refine the treatment of, for example, prosthesis-related infection. Methods: We examined different target points; Staphylococcus aureus biofilm (68Ga-labeled DOTA-K-A9 and DOTA-GSGK-A11), bone remodeling ([18F]NaF), bacterial cell membranes ([68Ga]Ga-Ubiquicidin), and leukocyte trafficking ([68Ga]Ga-DOTA-Siglec-9). We compared them to the well-known glucose metabolism marker [18F]FDG, in a well-established juvenile S. aureus induced osteomyelitis (OM) pig model. Results: [18F]FDG accumulated in the OM lesions seven days after bacterial inoculation, but disappointingly we were not able to identify any tracer accumulation in OM with any of the supposedly more specific tracers. Conclusion: These negative results are, however, relevant to report as they may save other research groups from conducting the same animal experiments and provide a platform for developing and evaluating other new potential tracers or protocol instead.
Synthesis of Au, Ag, and Au–Ag Bimetallic Nanoparticles Using Pulicaria undulata Extract and Their Catalytic Activity for the Reduction of 4-Nitrophenol
Authors: Khan Merajuddin , Al-hamoud Khaleel , Liaqat Zainab , Shaik Mohammed Rafi , Adil Syed Farooq , Kuniyil Mufsir , Alkhathlan Hamad Z. , Al-Warthan Abdulrahman , Siddiqui Mohammed Rafiq H. , Mondeshki Mihail , Tremel Wolfgang , Khan Mujeeb , Tahir Muhammad Nawaz
Published: September 2020

Plant extract of Pulicaria undulata (L.) was used as both reducing agent and stabilizing ligand for the rapid and green synthesis of gold (Au), silver (Ag), and gold–silver (Au–Ag) bimetallic (phase segregated/alloy) nanoparticles (NPs). These nanoparticles with different morphologies were prepared in two hours by stirring corresponding metal precursors in the aqueous solution of the plant extracts at ambient temperature. To infer the role of concentration of plant extract on the composition and morphology of NPs, we designed two different sets of experiments, namely (i) low concentration (LC) and (ii) high concentration (HC) of plant extract. In the case of using low concentration of the plant extract, irregular shaped Au, Ag, or phase segregated Au–Ag bimetallic NPs were obtained, whereas the use of higher concentrations of the plant extract resulted in the formation of spherical Au, Ag, and Au–Ag alloy NPs. The as-prepared Au, Ag, and Au–Ag bimetallic NPs showed morphology and composition dependent catalytic activity for the reduction of 4-nitrophenol (4-NPh) to 4-aminophenol (4-APh) in the presence of NaBH4. The bimetallic Au–Ag alloy NPs showed the highest catalytic activity compared to all other NPs.
Improving the Cycling Stability of Fe3O4/NiO Anode for Lithium Ion Battery by Constructing Novel Bimodal Nanoporous Urchin Network
Authors: Zhang Xiaomin , Liu Xiaoli , Zhou Jun , Qin Chunling , Wang Zhifeng
Published: September 2020

The development of facile preparation methods and novel three-dimensional structured anodes to improve cycling stability of lithium ion batteries (LIBs) is urgently needed. Herein, a dual-network ferroferric oxide/nickel oxide (Fe3O4/NiO) anode was synthesized through a facile dealloying technology, which is suitable for commercial mass manufacturing. The dual-network with high specific surface area contains a nanoplate array network and a bimodal nanoporous urchin network. It exhibits excellent electrochemical performance as an anode material for LIB, delivering a reversible capacity of 721 mAh g−1 at 100 mA g−1 after 100 cycles. The good lithium storage performance is related to the ample porous structure, which can relieve stress and mitigate the volume change in the charge/discharge process, the interconnected porous network that enhances ionic mobility and permeability, and synergistic effects of two kinds of active materials. The paper provides a new idea for the design and preparation of anode materials with a novel porous structure by a dealloying method and may promote the development of the dealloying field.
Hematological Alterations Related to Treatment with Teriflunomide and Dimethyl Fumarate in Multiple Sclerosis
Authors: García-Estévez Daniel Apolinar
Published: September 2020

The exact mechanism of action of different modifying treatments in the evolutionary course of multiple sclerosis (MS) remains unknown, but it is assumed that they act upon the cells involved in acquired immunity. One effect of these treatments is the development of lymphopenia, which carries inherent safety risks. This study was conducted to understand the alterations that teriflunomide (TERI) and dimethyl fumarate (DMF) exert upon white blood cells in a series of patients with MS. This study included a total of 99 patients; 44 treated with DMF and 55 patients treated with TERI. Blood counts were evaluated at baseline and every 6 months in order to track the absolute leukocyte, lymphocyte, and neutrophil counts. Twelve months after starting treatment, we observed a significant decrease in leukocytes (21.1%), lymphocytes (39.1%), and neutrophils (10%) in the DMF group. In the TERI group, leukocytes decreased by 11.1%, lymphocytes by 8.1%, and neutrophils by 15.7%. Both TERI and DMF produced a significant decrease in leukocytes during the first year of treatment and this was mainly related with a decrease in neutrophils in the TERI group and a decrease in lymphocytes in the DMF group.
Branched-Chain Fatty Acids—An Underexplored Class of Dairy-Derived Fatty Acids
Authors: Taormina Victoria M. , Unger Allison L. , Schiksnis Morgan R. , Torres-Gonzalez Moises , Kraft Jana
Published: September 2020

Dairy fat and its fatty acids (FAs) have been shown to possess pro-health properties that can support health maintenance and disease prevention. In particular, branched-chain FAs (BCFAs), comprising approximately 2% of dairy fat, have recently been proposed as bioactive molecules contributing to the positive health effects associated with the consumption of full-fat dairy products. This narrative review evaluates human trials assessing the relationship between BCFAs and metabolic risk factors, while potential underlying biological mechanisms of BCFAs are explored through discussion of studies in animals and cell lines. In addition, this review details the biosynthetic pathway of BCFAs as well as the content and composition of BCFAs in common retail dairy products. Research performed with in vitro models demonstrates the potent, structure-specific properties of BCFAs to protect against inflammation, cancers, and metabolic disorders. Yet, human trials assessing the effect of BCFAs on disease risk are surprisingly scarce, and to our knowledge, no research has investigated the specific role of dietary BCFAs. Thus, our review highlights the critical need for scientific inquiry regarding dairy-derived BCFAs, and the influence of this overlooked FA class on human health.
Vitamin D Correction Down-Regulates Serum Amyloid P Component Levels in Vitamin D Deficient Arab Adults: A Single-Arm Trial
Authors: Amer Osama , Khattak Malak , Alnaami Abdullah , Aljohani Naji , Al-Daghri Nasser
Published: September 2020

Vitamin D (VD) has been observed to have anti-inflammatory properties. However, the effects of VD supplementation on the serum amyloid P component (SAP) has not been established. This study aimed to investigate the effect of VD supplementation on serum SAP levels in Arab adults. A total of 155 VD-deficient adult Saudis (56 males and 99 females) were recruited in this non-randomized, 6-month, single-arm trial. The intervention was as follows; cholecalciferol 50,000 international units (IU) every week for the first 2 months, followed by 50,000 twice a month for the next two months, and for the last two months, 1000 IU daily. Serum 25(OH)D, SAP, C-reactive protein (CRP), lipid profile, and glucose were assessed at baseline and post-intervention. At post-intervention, VD levels were significantly increased, while SAP levels significantly decreased in all study participants. Remarkably, this reduction in SAP was more significant in males than females after stratification. SAP was inversely correlated with VD overall (r = −0.17, p < 0.05), and only in males (r = −0.27, p < 0.05) after stratification according to sex after 6 months of VD supplementation. Such a relationship was not observed at baseline. VD supplementation can favorably modulate serum SAP concentrations in Arab adults, particularly in males.
Beyond Body Weight: Design and Validation of Psycho-Behavioural Living and Eating for Health Segments (LEHS) Profiles for Social Marketing
Authors: Brennan Linda , Chin Shinyi , Molenaar Annika , Barklamb Amy M. , Lim Megan SC , Reid Mike , Truby Helen , Jenkins Eva L. , McCaffrey Tracy A.
Published: September 2020

Obesity, sedentary behaviour, and poor dietary habits amongst young adults are growing concerns, with this age group being in a worse state of health and nutrition than adolescents and adults. This paper presents the procedures for establishing a new instrument for defining behaviours in relation to healthy lifestyle and food choices amongst young adults (Living and Eating for Health Segments: LEHS). The aim of this paper is to outline the instrument design protocol for external validation and to permit replication in other studies. The instrument design process used a multi-step social marketing instrument design method. This approach has previously been used in designing valid and reliable measures in marketing and consumer research, including social marketing. The protocol established six psycho-behavioural LEHS profiles for young adults. These profiles are: Lifestyle Mavens (15.4%), Aspirational Healthy Eaters (27.5%), Balanced-all Rounders (21.4%), Health Conscious (21.1%), Contemplating Another Day (11.2%), and Blissfully Unconcerned (3.4%). Each of these profiles provided insights into psycho-behavioural characteristics that can be used in designing apposite social media social marketing campaigns.
Impact Strength and Water Uptake Behavior of Bleached Kraft Softwood-Reinforced PLA Composites as Alternative to PP-Based Materials
Authors: Oliver-Ortega Helena , Tarrés Quim , Mutjé Pere , Delgado-Aguilar Marc , Méndez José Alberto , Espinach Francesc Xavier
Published: September 2020

The research toward environmentally friendly materials has devoted a great effort on composites based on natural fiber-reinforced biopolymers. These materials have shown noticeable mechanical properties, mainly tensile and flexural strengths, as a consequence of increasingly strong interfaces. Previous studies have shown a good interface between natural fibers and poly (lactic acid) (PLA) when these fibers present a low lignin content in their surface chemical composition (bleached fibers). Nonetheless, one of the main drawbacks of these materials is the hydrophilicity of the reinforcements in front of the mineral ones like glass fiber. Meanwhile, the behavior of such materials under impact is also of importance to evaluate its usefulness. This research evaluates the water uptake behavior and the impact strength of bleached Kraft softwood-reinforced PLA composites that have been reported to show noticeable tensile and flexural properties. The paper explores the differences between these bio-based materials and commodity composites like glass fiber-reinforced polypropylene.
Fatigue Behavior of 3D Braided Composites Containing an Open-Hole
Authors: Liang Shuangqiang , Zhou Qihong , Mei Haiyang , Chen Ge , Ko Frank
Published: September 2020

The static and dynamic mechanical performances of notched and un-notched 3D braided composites were studied. The effect of longitudinal laid-in yarn was investigated in comparison with low braiding angle composites. The specimens were fatigue tested for up to millions of cycles, and the residual strength of the samples that survived millions of cycles was tested. The cross-section of the 3D braided specimens was observed after fatigue loading. It was found that the static and fatigue properties of low angle 3D braided behaved better than longitudinally reinforced 3D braided composites. For failure behavior, pure braids contain damage better and show less damage area than the braids with longitudinal yarns under fatigue loading. More cracks occurred in the 3D braided specimen with axial yarn cross-section along the longitudinal and transverse direction.
Efficient Production of Poly(Cyclohexene Carbonate) via ROCOP of Cyclohexene Oxide and CO2 Mediated by NNO-Scorpionate Zinc Complexes
Authors: Sobrino Sonia , Navarro Marta , Fernández-Baeza Juan , Sánchez-Barba Luis F. , Lara-Sánchez Agustín , Garcés Andrés , Castro-Osma José A. , Rodríguez Ana M.
Published: September 2020

New mono- and dinuclear chiral alkoxide/thioalkoxide NNO-scorpinate zinc complexes were easily synthesized in very high yields, and characterized by spectroscopic methods. X-ray diffraction analysis unambiguously confirmed the different nuclearity of the new complexes as well as the variety of coordination modes of the scorpionate ligands. Scorpionate zinc complexes 2, 4 and 6 were assessed as catalysts for polycarbonate production from epoxide and carbon dioxide with no need for a co-catalyst or activator under mild conditions. Interestingly, at 70 °C, 10 bar of CO2 pressure and 1 mol % of loading, the dinuclear thioaryloxide [Zn(bpzaepe)2{Zn(SAr)2}] (4) behaves as an efficient and selective one-component initiator for the synthesis of poly(cyclohexene carbonate) via ring-opening copolymerization of cyclohexene oxide (CHO) and CO2, affording polycarbonate materials with narrow dispersity values.
Microwave-Assisted Pyrolysis of Biomass Waste: A Mini Review
Authors: Ethaib Saleem , Omar Rozita , Kamal Siti Mazlina Mustapa , Awang Biak Dayang Radiah , Zubaidi Salah L.
Published: September 2020

The utilization of biomass waste as a raw material for renewable energy is a global concern. Pyrolysis is one of the thermal treatments for biomass wastes that results in the production of liquid, solid and gaseous products. Unfortunately, the complex structure of the biomass materials matrix needs elevated heating to convert these materials into useful products. Microwave heating is a promising alternative to conventional heating approaches. Recently, it has been widely used in pyrolysis due to easy operation and its high heating rate. This review tries to identify the microwave-assisted pyrolysis treatment process fundamentals and discusses various key operating parameters which have an effect on product yield. It was found that several operating parameters govern this process such as microwave power and the degree of temperature, microwave absorber addition and its concentration, initial moisture content, initial sweep gas flow rate/residence time. Moreover, this study highlighted the most attractive products of the microwave pyrolysis process. These products include synthesis gas, bio-char, and bio-oil. The benefits and challenges of microwave heating are discussed.
Extended Target Marginal Distribution Poisson Multi-Bernoulli Mixture Filter
Authors: Du Haocui , Xie Weixin
Published: September 2020

The existence of clutter, unknown measurement sources, unknown number of targets, and undetected probability are problems for multi-extended target tracking, to address these problems; this paper proposes a gamma-Gaussian-inverse Wishart (GGIW) implementation of a marginal distribution Poisson multi-Bernoulli mixture (MD-PMBM) filter. Unlike existing multiple extended target tracking filters, the GGIW-MD-PMBM filter computes the marginal distribution (MD) and the existence probability of each target, which can shorten the computing time while maintaining good tracking results. The simulation results confirm the validity and reliability of the GGIW-MD-PMBM filter.
Photometric Stereo-Based Depth Map Reconstruction for Monocular Capsule Endoscopy
Authors: Hao Yang , Li Jing , Meng Fei , Zhang Peisen , Ciuti Gastone , Dario Paolo , Huang Qiang
Published: September 2020

The capsule endoscopy robot can only use monocular vision due to the dimensional limit. To improve the depth perception of the monocular capsule endoscopy robot, this paper proposes a photometric stereo-based depth map reconstruction method. First, based on the characteristics of the capsule endoscopy robot system, a photometric stereo framework is established. Then, by combining the specular property and Lambertian property of the object surface, the depth of the specular highlight point is estimated, and the depth map of the whole object surface is reconstructed by a forward upwind scheme. To evaluate the precision of the depth estimation of the specular highlight region and the depth map reconstruction of the object surface, simulations and experiments are implemented with synthetic images and pig colon tissue, respectively. The results of the simulations and experiments show that the proposed method provides good precision for depth map reconstruction in monocular capsule endoscopy.
Social Entrepreneurship: Dissection of a Phenomenon through a German Lens
Authors: Cagarman Karina , Kratzer Jan , Osbelt Katharina
Published: September 2020

The occurrence and scientific investigation of the phenomenon of social entrepreneurship are rather new. The term is very popular among politicians and is reflected in a lot of the political demands and willingness that they express. However, a review of the literature about it shows that there is no common ground or frame, and the historical developments are different in different countries and economies. Based on a study of the literature, a two-phase survey following the ‘Policy Delphi’ approach was conducted in Germany in order to enlighten this frameless picture of social entrepreneurship. Our results indicate five dimensions that extend the core term: ‘social’, namely ‘Societal–Visionary’, ‘Ecological’, ‘Societal–Entrepreneurial’, ‘Economic’, and ‘Innovative–Entrepreneurial’. The degree of intercorrelation among the five dimensions shows that four factors, namely ‘Societal–Visionary’, ‘Societal–Entrepreneurial’, ‘Economic’, and ‘Innovative–Entrepreneurial’, have low to medium-high correlations. The fifth factor, ‘Ecological’, has the weakest correlation with all other factors.
An Exploratory Analysis of Networked and Spatial Characteristics of International Natural Resource Trades (2000–2016)
Authors: Wang Yujing , Ren Fu , Zhu Ruoxin , Du Qingyun
Published: September 2020

Natural resources, as the material basis of human life and production, play a crucial role in national economic and social development. It is essential to reveal the structural characteristics of global natural resource supply and demand, which has become one of the most critical factors affecting every country’s policy strategy and economic development. However, mining the characteristics of international natural resource trades is a huge challenge because of the availability and quality of trade data. In this study, the international natural resource trade system is modeled as networks based on the available bilateral trade data from 2000 to 2016. Complex network methods and spatial analysis are utilized to explore the networked and spatial characteristics of different international natural resource trade networks (INRTNs). First, we quantitatively present the overall evolution trend of INRTNs by calculating several indicators of network features at the macrolevel. Then, as the intermediate-level characteristics of INRTNs, the core–periphery structures are explored by applying hierarchical clustering and a visual matrix heatmap. Finally, at the microlevel, the imbalance in direction is detected through the combination of node importance in a complex network with bivariate choropleth maps of spatial analysis. The empirical evidence from INRTNs of different product types in this paper will help governments and business administrations to perceive the complex natural resource trade environment, which can instruct policymakers to formulate effective import–export policies and ensure national resource security and sustainable development.
Hybrid CHP/Geothermal Borehole System for Multi-Family Building in Heating Dominated Climates
Authors: Alqaed Saeed , Mustafa Jawed , P. Hallinan Kevin , Elhashmi Rodwan
Published: September 2020

A conventional ground-coupled heat pump (GCHP) can be used to supplement heat rejection or extraction, creating a hybrid system that is cost-effective for certainly unbalanced climes. This research explores the possibility for a hybrid GCHP to use excess heat from a combined heat power (CHP) unit of natural gas in a heating-dominated environment for smart cities. A design for a multi-family residential building is considered, with a CHP sized to meet the average electrical load of the building. The constant electric output of the CHP is used directly, stored for later use in a battery, or sold back to the grid. Part of the thermal output provides the building with hot water, and the rest is channeled into the GCHP borehole array to support the building’s large heating needs. Consumption and weather data are used to predict hourly loads over a year for a specific multi-family residence. Simulations of the energies exchanged between system components are performed, and a cost model is minimized over CHP size, battery storage capacity, number of boreholes, and depth of the borehole. Results indicate a greater cost advantage for the design in a severely heated (Canada) climate than in a moderately imbalanced (Ohio) climate.
Sustainable Profit versus Unsustainable Growth: Are Venture Capital Investments and Governmental Support Medicines or Poisons?
Authors: Kang Moon Young
Published: September 2020

Considering that startups greatly contribute to the economic development and survival of a country through economic growth and job creation, it is necessary to investigate the profitability of startups. However, research on this issue has not been developed enough as most previous studies regarding firm profitability were based on large-scale public companies with relatively easy data accessibility, not on startups. In addition, it is meaningful to empirically prove whether venture capital investments and governmental support positively impact on the sustainability of startups as huge discrepancies exist between traditional academic research and recent practices. Findings from this study, based on data analytics, are expected to fill the gap in knowledge as it is not clearly known about firm profitability of startups for their sustainable growth and survival. Focusing on startup profitability, the main objective of this research is to provide significant theoretical contributions and practical guidelines for startup entrepreneurs, investors, and policymakers to avoid unsubstantial growth and find solutions for sustainable growth and survival. To properly and completely analyze the determinants of firm profitability of startups, this research used the 2018 and 2019 Survey of Korean Startups by the Ministry of SMEs and Startups of Korea and Korea Venture Business Association with over 3000 samples.
Different Perceptions of Belief: Predicting Household Solid Waste Separation Behavior of Urban and Rural Residents in China
Authors: Lou Tianyang , Wang Deyong , Chen Huili , Niu Dongjie
Published: September 2020

An unprecedented Household Solid Waste (HSW) separation program was launched in 46 cities and some pilot rural areas in China in 2019. This study examines the antecedents of waste separation behavior using the extended theory of planned behavior (TPB) to identify beliefs that are useful targets for interventions, and compares the urban-rural differences. Based on interviews with rural and urban residents, we identified residents’ beliefs influencing waste separation behaviors, including four behavioral, seven normative, and eight control beliefs. Then, we tested the conceptual model with a two-stage questionnaire survey using a sample of 604 residents from urban and rural areas. Evidence from structural equation modeling supports the extended TPB in that it predicts waste separation intention and behavior on the whole. Moral norm and self-identity were found to independently predict intention and may prove a useful addition to the TPB; however, the path from attitude to intention is not supported in both urban and rural models. Moreover, the specific difference of belief between urban and rural residents was examined. The behavioral beliefs associated to money, including earning, free waste bin or bag, and fine, are significant only in the rural group. The normative beliefs of family, Chinese Communist Party (CCP) members, and government can affect residents’ subjective norm in both urban and rural, while the beliefs of relatives, friends, and neighbors are significant only in the rural group. Implications for managers of operating waste separation programs were discussed. Further investigation into the potential of the model to intervene in waste separation behavior is required.
Mediation Effect of Adaptive Planning between Social Capital and Business Innovation: Application to a Community of Pisco Producers in Peru
Authors: Avalo-Ortega José A. , Yagüe-Blanco José L. , Vara-Horna Arístides , Cangahuala Allain Guillermo
Published: September 2020

This study addresses the effects linking adaptive planning and social capital that drive business innovation. A case study has been selected that involves a community of pisco producers, grouped around a production innovation and technology transfer center (CITE agroindustrial) in the southern part of Lima, Peru. The study examines how their perceptions have changed over a six-year period (2012–2018). Results show the mediation effect that adaptive planning—promoted through CITE activities—has between social capital and innovation, which is also strengthened over time. In conjunction with this, a route is investigated for business innovation that goes further than the need–opportunity dichotomy, through associative and collaborative behaviors, and adaptive planning that stands out thanks to its actors (the community of producers). This represents a path for transforming needs into opportunities for innovation and development.
Determinants of the Relationship of Medical Service Entities in the Virtual Environment
Authors: Matysiewicz Justyna , Smyczek Sławomir
Published: September 2020

Introducing new technologies to the healthcare market provides unique opportunities for implementing a powerful framework of resources, tools, and applications that can revolutionize the ways in which medical units interact with their patients, as well as help deliver and manage medical services. The Internet of Services, as a new concept of Internet evaluation, depends not only on technological solutions but also on service innovations in the field of new value propositions where a patient-centered model is needed. Such a model would consider patient preferences, values, and the need for information as the leading characteristics of care. Patient and medical unit engagement is an essential prerequisite for the new value proposition development process. In this paper, we focus on the identification and analysis of the determinants responsible for the mutual engagement of patients and medical units. The purpose of this study was to identify and describe a relational model for the virtual healthcare service market. This study adopted a quantitative survey approach. The questionnaire was based on a three-factor model of consumer behavior, considering motivation, capacity, and opportunities. The relationships between patients and healthcare organizations will develop on the condition that the patients are properly motivated and have adequate abilities to become engaged in the relationships with health care providers.
Ecosystem Service Multifunctionality: Decline and Recovery Pathways in the Amazon and Chocó Lowland Rainforests
Authors: Eguiguren Paul , Ojeda Luna Tatiana , Torres Bolier , Lippe Melvin , Günter Sven
Published: September 2020

The balance between the supply of multiple ecosystem services (ES) and the fulfillment of society demands is a challenge, especially in the tropics where different land use transition phases emerge. These phases are characterized by either a decline (from intact old-growth to logged forests) or a recovery of ES (successional forests, plantations, and agroforestry systems). This highlights the importance of ecosystem service multifunctionality (M) assessments across these land use transition phases as a basis for forest management and conservation. We analyzed synergies and trade-offs of ES to identify potential umbrella ES. We also evaluated the impact of logging activities in the decline of ES and M, and the influence of three recovery phases in the supply of ES and M. We installed 156 inventory plots (1600 m2) in the Ecuadorian Central Amazon and the Chocó. We estimated indicators for provisioning, regulating, supporting services and biodiversity. M indicator was estimated using the multifunctional average approach. Our results show that above-ground carbon stocks can be considered as an umbrella service as it presented high synergetic relations with M and various ES. We observed that logging activities caused a decline of 16–18% on M, with high impacts for timber volume and above-ground carbon stocks, calling for more sustainable practices with stricter post-harvesting control to avoid a higher depletion of ES and M. From the recovery phases it is evident that, successional forests offer the highest level of M, evidencing high potential to recover multiple ES after human disturbance.
Land-Use Conflict in the Gran Chaco: Finding Common Ground through Use of the Q Method
Authors: Zepharovich Elena , Ceddia Michele Graziano , Rist Stephan
Published: September 2020

In a world characterized by ongoing overexploitation of finite resources—such as land and forests—stakeholder conflicts over use of remaining resources occur frequently and are likely to intensify. There is increasing awareness of the need to better understand individual stakeholders’ perspectives, which often condition behavior, in order to address conflicts and inform wider policymaking. We used the Q method to capture the perspectives of diverse stakeholders and highlight consensus and distinguishing statements. Our results bring to the fore three main perspectives on deforestation (development, family agriculture, and subsistence) and several points of agreement and disagreement. The strongest disagreement concerns the benefits and costs of deforestation: the development perspective portrays benefits as mutual and costs as marginal, whereas the family agriculture and subsistence perspectives associate no benefits and extreme costs with deforestation—including loss of livelihoods and culture. Nevertheless, stakeholder consensus emerges on other points—especially the need for participatory long-term strategies of land use. This paper shows how the Q method can be applied to better understand land-use conflicts.
Edible Biological Resource Use in an Agricultural Heritage System and Its Driving Forces: A Case of the Shuangjiang Mengku Ancient Tea and Culture System
Authors: Ma Nan , He Siyuan , Min Qingwen
Published: September 2020

An agricultural heritage system is a special type of protected area that is both culturally and ecologically important. Biological resources are an essential component of an agricultural heritage system. They are necessary to support human livelihood, and their usage is key to ensuring biodiversity. This study used a survey questionnaire and key informant interviews to investigate the use of edible biological resources (EBRs) in the Shuangjiang Mengku ancient tea and culture system (SMATCS). We investigated similarities and differences in EBR use between four minority groups as well as the driving forces behind them. The four groups used 245 EBR species in 113 families, and diversity of EBR use was found in terms of species, edible parts, harvest season, and usage. EBR use within groups was driven by natural, cultural, social, and economic forces. Two social factors (infrastructure and communication), two economic factors (overall economic development and farmer income), and a biological resource (species diversity) drove EBR utilization in all the groups convergently, while three cultural factors drove EBR utilization divergently. To assure the long-term sustainability of EBRs, the preservation of cultural diversity should be combined with the conservation of biodiversity. Targets must be set to adjust the impacts of the driving factors, and more stakeholders must be involved in the conservation of EBRs.