bluuebunny/crossref_metadata_2025 huggingface dataset:
Percepção dos pacientes em tratamento de diálise peritoneal quanto aos riscos de infecções durante as práticas assépticas domiciliares
Authors: Santana Rosane da Silva , Silva Antônia Samara Alves da , Santos Wesley Fernandes dos , Santos Jorgiana Moura dos , Silva Ícaro Avelino , Barbosa Miralice Medeiros Ferreira , Serrão Virgínia Carneiro Marques , Silva Francisca Jéssica Abreu da , Feitosa Jéssica Mykaella Ferreira , Soares Nivia Cristiane Ferreira Brandão
Published: December 2020

A Diálise Peritoneal é uma modalidade de tratamento para os pacientes com Doença Renal Crônica e apresenta benefícios como o retorno dos pacientes a uma vida praticamente normal em função da autonomia do autocuidado e da facilidade de tratamento em domicílio. O objetivo do estudo foi conhecer a percepção dos pacientes em tratamento de diálise peritoneal quanto aos riscos de infecções durante as práticas assépticas domiciliares. Estudo exploratório com abordagem qualitativa descritiva, realizado nos meses de março a junho de 2019 em uma Clínica Particular de Nefrologia de Teresina-PI. Foram incluídos no estudo pacientes adultos em tratamento de Diálise Peritoneal com idade acima de 18 anos e, excluídos aqueles que se encontravam debilitados, com restrições cognitivas ou psicológicas. Para coleta dos dados foi utilizado um roteiro de entrevista semiestruturado com dados sobre as características sociodemográficas do grupo entrevistado e questões abertas sobre os riscos de infecção e os cuidados com o cateter de DP. Os resultados foram interpretados e discutidos de acordo com a Análise de Conteúdo. Verificou-se que a maioria dos pacientes apresentou infecção no orifício de saída do cateter e em alguns casos a peritonite, que possivelmente foram adquiridas por erros de procedimento durante o autocuidado com o cateter de Diálise Peritoneal. Mesmo com recebimento de um treinamento instrutivo pela equipe de saúde sobre o tratamento, material utilizado, cuidados domiciliares, métodos assépticos, entre outros, os pacientes apresentaram dificuldades no manuseio do cateter DP. É necessário que a equipe multidisciplinar em saúde repense a lógica de construção dos saberes dos pacientes com Diálise Peritoneal, procurando identificar a abordagem que oriente o tratamento quando realizado no domicílio.
A importância da enfermagem para uma execução efetiva do método canguru
Authors: Brito Ana Carla Muniz de , Ferreira Adriele de Fátima Cardoso , Sobrinho Celice Ruanda Oliveira , Rocha Diane do Socorro Alves , Oliveira Danielle Farias da Costa , Costa Laura Arruda , Martins Ruth de Souza , Parente Jorgeany Soares
Published: December 2020

Método canguru tem como principal eixo a família e a promoção do contato pele a pele, promovendo a regulação da térmica do RN, além de promover aleitamento materno, redução da dor neonatal, menor risco de infecção neonatal e redução do período de internação. O objetivo desta revisão é identificar as atribuições do enfermeiro diante dos cuidados atribuídos no método canguru descritas em artigos publicados entre os anos de 2015 a 2020. Na metodologia foi utilizado o software IRAMUTEQ® (Interface de R pour lês Analyses Multidimensionnelles de Textes et de Questionnaires) para processamento e análise do corpus textual feito a partir dos articos levantados atraves das bases de dados. Nos resultados encontramos inicialmente 335 artigos em ambos os bancos de dados BDENF, LILACS, SCIELO e MEDLINE, no entanto, ao aplicar os filtros de inclusão e exclusão, restaram apenas 12 artigos. Através do nosso estudo foi possível notar que o método canguru tem eficiência comprovada e diversos benefícios porém ainda apresenta barreiras em sua implementação. A enfermagem participa ativamente na gerência, nos cuidados de acolhimento, educação, intervenções, estimulação e orientação de modo a promover o contato pele a pele, o desenvolvimento do bebê, o fortalecimento de laços afetivos e promoção do aleitamento.
Relação entre microbiota intestinal e depressão
Authors: Ratto Rafaela da Silva , Afonso Max dos Santos , Bampi Suely Ribeiro , Peter Nathalia Brandão , Raphaelli Chirle de Oliveira , Ratto Cleber Gibbon
Published: December 2020

A pesquisa descreve o distúrbio da depressão e a sua relação com a microbiota intestinal humana, o que leva o indivíduo a estar em disbiose e a sua associação com a patologia. Neste contexto, foi possível enfatizar a importância do tratamento nutricional para esses casos. Como metodologia realizou-se uma pesquisa de revisão bibliográfica, qualitativa e descritiva. A busca das informações científicas disponíveis na literatura ocorreu nas bases de dados eletrônicas Scielo, Google Acadêmico e Pubmed. Foram pesquisados artigos que abordam doenças do foro mental com a microbiota humana, levando em consideração o que de tão eminente pode ocorrer na modulação intestinal e que possa acarretar doenças psíquicas como a depressão, e, por consequência, os danos que os tratamentos com antidepressivos trazem para nossa modulação intestinal, publicados entre os anos de 1997 a 2019, nas línguas portuguesa e inglesa. O diagnóstico da depressão tem origem através de muitas variáveis, porém através desta pesquisa é possível identificar um de tantos motivos para tal patologia, como a disbiose intestinal causada pela má alimentação, uso de fármacos para tratar a mesma patologia e a permeabilidade inadequada desse trato gastrointestinal. A nutrição tem papel fundamental nesses casos, tanto para a prevenção de patologias e distúrbios psíquicos como a depressão, e também para o auxílio no seu tratamento junto a especialista como psicólogos e psiquiatras, mesmo sabendo da importância da nutrição no tratamento e prevenção da depressão, ainda é muito pouco falado sobre esse tipo de auxílio, a mudança de hábitos como a alimentação.
Os territórios existenciais e a Saúde Coletiva: antes e depois da pandemia
Authors: Amorim Annibal Coelho de , Machado Katia da Silva , Silva Milene Zanoni da , Sérgio Juraci Vieira , Ghelman Ricardo , Barreto Adalberto
Published: December 2020

O tema Comunicação e Informação em Saúde ganha enorme relevância diante da pandemia do Covid-19 e seus impactos na vida de milhões de pessoas ao redor do planeta, afetadas direta ou indiretamente pelos planos de ação adotado em cidades, territórios, países e continentes. Estatísticas da pandemia refletem aumento da perda de vidas, enquanto, atônitos ou desorganizados, governos tentam gerir informações no enfrentamento do novo coronavírus, decretada pela OMS (WHO) em março de 2020. O artigo aborda o binômio comunicação e informação em saúde, como parte das estratégias sanitárias de enfrentamento da pandemia e examina a mobilização popular da vigilância em saúde nos territórios existenciais, como um conceito de caráter filosófico.
Disfunções olfativas e gustativas na COVID-19
Authors: Santos Ianka Heloisa Alencar , Andrade Thandara Rejane Santos Ferreira , Torres Erivelton Cunha , Freitas Aparecida Praxedes de Oliveira , Jesus Carla Viviane Freitas de , Ferrari Yasmim Anayr Costa
Published: December 2020

Objetivo: Analisar a prevalência das disfunções olfativas e gustativas presentes na COVID-19 e suas implicações para os pacientes. Métodos: Revisão Integrativa da literatura realizada através de buscas nas bases de dados Literatura Latino-americana e do Caribe em Ciências da Saúde, Medical Literature Analysis and Retrieval System Online e Scientific Electronic Library Online. Os descritores foram combinados aos pares em “Transtornos do Olfato AND COVID-19” e “Ageusia AND COVID-19”. Foram incluídos artigos disponíveis na íntegra, em português, inglês e espanhol; originais e revisões sistemáticas; publicados de janeiro a 01 de agosto de 2020; com metodologia coesa e bem delineada. Foram excluídos os artigos de revisão integrativa, bibliográfica e com duplicidade nas bases de dados. Resultados: A amostra final foi composta por 10 artigos. Elaborou-se uma tabela com o ano de publicação, autores, país, tipo de artigo, nível de evidência e objetivo dos estudos. Conclusão: As disfunções olfativas e gustativas são indicadores comuns da infecção pela COVID-19 e podem se desenvolver no início do quadro clínico, persistindo ou não após o término de tratamento. Dessa forma, os indivíduos devem ser orientados pelos profissionais de saúde sobre a necessidade de isolamento social e tratamento adequados, visando a interrupção da transmissão do agente infeccioso.
Investigação sobre a influência da cefaleia na qualidade de vida dos estudantes de diferentes anos do curso de medicina de uma instituição de São José do Rio Preto
Authors: Mazucato Juliana Bertassi , Ferrarezi Fernando Carpentieri , Lima Luiza Cavalero de , Favaro Paula Freitas , Pozo Marina
Published: December 2020

A migrânea é um sintoma muito comum na população geral, expressando-se com uma prevalência de mais de 90% ao longo da vida, podendo ser caracterizada como um tipo de cefaleia primária definida como um distúrbio neurovascular crônico, com manifestação clínica determinada por crises intervaladas de cefaleia relacionadas a sintomas como fotofobia, fonofobia, náusea, vômito, sendo frequente também a ocorrência de sintomas neurológicos. A classificação internacional de cefaleia apresenta categorias das diferentes dores de cabeça em tipos e subtipos, sendo os mais comuns a cefaleia tensional e a migrânea com ou sem aura. Os estudantes universitários constituem uma população de risco para migrânea e cefaleia tensional, sendo que se estas comorbidades não forem tratadas podem evoluir para a forma crônica afetando diretamente na qualidade de vida destes indivíduos. O objetivo do trabalho proposto foi avaliar a influência da cefaleia na qualidade de vida dos estudantes de diferentes anos do curso de medicina e estabelecer uma relação entre os anos de graduação e a piora da dor. O estudo foi realizado de modo descritivo prospectivo com 240 alunos. Observou-se que as dores são cada vez mais frequentes ao longo do curso, contudo grande parte dos entrevistados não consideraram que a qualidade de vida foi afetada pela afecção, indicando uma possível adaptação da dor sem que esta afete as atividades diárias. Com os dados obtidos, mostrou-se necessário uma maior propagação sobre os fatores desencadeantes das crises, e a importância da procura pelo Neurologista para o correto diagnóstico e tratamento.
REGULASI DAN MEKANISME IMPOR LIMBAH NON-BAHAN BERBAHAYA DAN BERACUN DALAM RANGKA PERLINDUNGAN DAN PENGELOLAAN LINGKUNGAN HIDUP
Authors: Evita Liza , Galingging Ridarson
Published: December 2020

Limbah Non B3 sebagai Bahan Baku Industri dapat diimpor apabila: tidak berasal dari kegiatan landfill, bukan sampah dan tidak tercampur sampah, tidak terkontaminasi B3 dan Limbah B3, dan homogen. Penelitian hukum normatif. Bagaimana Regulasi dan Mekanisme Impor Limbah Non-Bahan Berbahaya Dan Beracun Dalam Rangka Perlindungan Dan Pengelolaan Lingkungan Hidup. Peraturan Menteri Perdagangan No 84 Tahun 2019, limbah non B3 dapat diimpor untuk bahan baku industri. Untuk mendapatkan Persetujuan Impor (PI), perusahaan harus mengajukan permohonan secara elektronik kepada Direktur Jenderal Perdagangan.
DASAR PEMBENTUKAN PERATURAN DAERAH DAN PERAN KEPALA DAERAH TERHADAP UPAYA PENCEGAHAN PENYEBARAN COVID-19
Authors: Rohman Abdul
Published: December 2020

Artikel ini membahas kedudukan peraturan daerah dan peran kepala daerah pencegahan penyebaran covid-19. Pemerintahan daerah, khususnya provinsi menjadi jantung pertahanan guna pencegahan keluar masuk orang dengan kebikajan yang dimilikinya. Fenomena covid-19 mendorong kepala daerah mengeluarkan kebijakan guna keselamatan warganya. Penulis menggunakan metode penelitian normatif yuridis, dengan pendekatan kulitatif untuk menganalisis permasalahan tersebut. Hasil dari penelitian diantaranya peraturan daerah berkedudukan sebagai payung hukum dalam upaya mencegah penyebaran Covid-19. Atribusi menjadi dasar kewenangan bagi pemerintah daerah membentuk kebijakan pada daerah otomom. Peran pemerintah daerah dalam mengeluarkan kebijakan-kebijakan, dimana pemerintah daerah ini sebagai pemerintahan konkuren yang melaksanakan Sebagian tugas pemerintah pusat pada daerahnya. Usaha pemerintah daerah untuk membantu program pemenrintahan umum, yang menjadi tugas pemerintah nasional dalam rangka kesetabilan nasional, sangat terlihat dalam usaha pencegahan penyebaran covid-19 ini.
KETAATAN DAN KEPATUHAN HUKUM MASYARAKAT TERHADAP PERATURAN PSBB MASA TRANSISI BEDASARKAN PERGUB NO. 88 TAHUN 2020 DI WILAYAH JAKARTA BARAT
Authors: Michelle Elizabeth , Betarli Lengkong Keyzia , Jusuf Melvin
Published: December 2020

Tahun 2020 dunia dikejutkan dengan adanya pandemi COVID-19 yang menimbulkan kepanikan dimana – mana serta banyak sekali korban jiwa. Banyak sekali Negara – Negara di dunia yang belum siap dalam menangani pandemi ini. Indonesia adalah contoh Negara yang belum siap dalam menangani pandemi COVID-19. Hal ini dibuktikan dengan meningkatnya warga yang terinfeksi virus COVID-19 terutama di wilayah Jakarta. Pemerintah Indonesia tidak hanya berdiam diri melainkan terus berusaha untuk melawan virus COVID-19 ini dengan membuat berbagai kebijakan. Salah satunya dengan menerapkan Pembatasan Sosial Berskala Besar (PSBB) kebijakan ini dilakukan pemerintah tujuannya adalah untuk mengurangi persebaran COVID-19 di Indonesia khususnya diwilayah Jakarta. Jakarta merupakan daerah dengan kasus COVID-19 tertinggi, untuk mengurangi kasus yang terjadi di Jakarta Pemerintah Daerah Khusus Ibukota Jakarta mengeluarkan PERGUB NO 88 TAHUN 2020 yang mengatur mengenai pelaksanaan Pembatasan Sosial Berskala Besar (PSBB). Peraturan yang dikeluarkan oleh Pemerintah Daerah tersebut merupakan langkah yang tepat tetapi yang terpenting menurut penulis untuk mengurangi kasus COVID-19 yang terjadi di Jakarta adalah dengan mentaati serta mematuhi peraturan tersebut. Oleh karena itu penelitian ini bertujuan untuk mengetahui ketaatan serta kepatuhan hukum masyarakat terhadap peraturan PSBB yang didasari oleh PERGUB NO 88 TAHUN 2020.
INFORMATION SYSTEM OF TUITION AND THESIS PAYMENT VERIFICATION WITH ADAPTIVE LAYOUT DESIGN
Authors: Adiwinoto Bambang , Japriadi Yohanes Setiawan , Tommy Lukas
Published: December 2020

The verification system of tuition and thesis payment at ISB Atma Luhur which is running is felt to be less effective and efficient because students must come directly to campus with proof of payment during working hours to verify the payment. Also, there is the possibility of negligence by the finance department that only stamped the payment slip without doing a flag, consequently, related students were unable to carry out the selection of lecture groups and thesis supervisors when the schedule began. This caused them to not get the favorite lecture groups and thesis supervisors because the quota had run out. To overcome this problem, an information system for verification of tuition payment and web-based thesis verification will be developed with an adaptive layout design so that it can be accessed by laptop or smartphone users without reducing comfort during operation. The system development model and tool used in this research are the waterfall model and the Unified Modeling Language (UML), respectively. The developed system can be used by students to upload proof of payment and monitor the verification status of proof of payment that was previously uploaded. The system can also be used by the finance department to verify payments, as well as display and print payment verification reports. The developed system can be accessed anywhere and anytime so that the efficiency and effectiveness of the verification process are increased.
PROVISION OF MICRO CREDIT AT BANK MANDIRI BOGOR WITH THE FUZZY TSUKAMOTO METHOD
Authors: Susliansyah Susliansyah , Nisan Nisan , Sumarno Heny , Priyono Hendro , Maulida Linda
Published: December 2020

It is an advantage for the bank, in this case, the Bank Mandiri Dramaga1 Bogor Unit, because of the increasing credit activity in banks, it is necessary to have an assessment in credit as consideration for prospective customers before the bank decides to accept or reject a prospective customer request. So it is necessary to develop a method that can assist and facilitate the bank in making decisions quickly and accurately. The basis for decision making is based on the criteria for determining who is eligible or not to receive a loan. To assist in determining whether someone is eligible or not to receive a loan, a decision support system is needed using fuzzy logic and applying the Tsukamoto method. The Lending Decision Support System was created to assist and facilitate the bank in making decisions to provide alternatives if a prospective customer applies for credit is accepted or not.
DESIGNING A ROUTER REDUCTION SYSTEM USING HOT STANDBY ROUTER PROTOCOL METHOD FOR BACKUP LINK IN DITJEN PPKL
Authors: Baskoro Andri Nuki , Anton Anton , Astuti Puji
Published: December 2020

Computer networks play an important role in data communication at companies or government institutions to support them in terms of work. In this case, the authors conducted observational research and direct interviews with IT staff at the Ditjen PPKL Control about how the network operates in that place. Routers have a very important role in data communication and connecting different networks, so a router reduction system is needed as a solution to minimize failures on the network or these devices. The network topology in each office or government agency is different, which makes the problems in each government office or agency different. Based on the research that has been done, the network of the Ditjen PPKL often experiences a link down which causes disconnection of the internet connection and hinders the productivity of staff. So a router redundancy system is needed to maintain network availability, such as the Hot Standby Router Protocol (HSRP) which has two lines, one as the mainline and the other as a backup if the mainline is down. That way network availability will always be maintained without having to wait for the IT staff to do troubleshooting if there is a network failure. The result of this research is to provide maintained network availability. Even if a link goes down, the network will automatically return to normal.
LOCATIO CONDUCTIO OPERIS’TE İŞ SAHİBİNİN MALZEMEYİ TEMİN ETME BORCU
Authors: SOYDAN Ceren
Published: December 2020

Roma hukukundaki kökenleri tartışmalı olan locatio conductio, Gaius’un Institutiones’inde rızai sözleşmeler kapsamında değerlendirilir. Eser sözleşmelerinde yüklenici, iş sahibinin vereceği ücret karşılığında ve iş sahibi tarafından verilen bir malzeme ile bir sonucu, eseri meydana getirmeyi ve teslim etmeyi üstlenir. Roma döneminde, eser sözleşmesinin kurulması için malzemenin iş sahibi tarafından verilmesi şarttı. Günümüzde yüklenici veya iş sahibi tarafından temin edilmesi herhangi bir önem taşımamaktadır.
Oral Healthcare Measures to Improve Overall Health in Older Adults
Authors: Onubogu Uloma , Mansfield W. Michael , Ozbek Irene N.
Published: December 2020

The purpose of this paper is to guide the understanding of preventive oral health measures to improve overall health in older adults. Oral health is a key indicator of overall health, well-being, and quality of life, yet, oral health status among older adults has remained alarmingly poor. Common oral conditions include dental decay, periodontal disease, tooth loss, dry mouth, and malodor. The connection between oral and systemic health has been established and this relationship is affected by various interrelated factors which pose many threats to older adults’ health. Documented factors may range from chronic diseases, use of medications, individual lifestyle, decline in cognitive and physical functioning, access to care, to several social indicators of oral health. Dental disease and poor oral health are largely preventable through healthy lifestyle behaviors and effective management of chronic systemic diseases. A collaborative team approach is necessary to ensure that older adults receive comprehensive care appropriate for their complex medical and dental needs.
The Effect of Postpartum Fatigue on Exclusive Breastfeeding Rates at Discharge: A Comparison of Birth Methods
Authors: Phillips Karen F , DePue Lisa , Mullen Spencer
Published: December 2020

Exclusive breastfeeding is recommended for the first six months of life due to the benefits it offers to both baby and mother. Although breastfeeding initiation rates are high, breastfeeding continuation rates at six and twelve months and exclusive breastfeeding rates remain lower than Healthy People recommendations. The purpose of this study was to determine if postpartum fatigue had any impact on the success of exclusive breastfeeding when comparing birth methods. Although postpartum fatigue has been reported as a common occurrence, less is known about its effect on exclusive breastfeeding rates. A quasi-experimental study with 157 participants was completed to evaluate the effect of postpartum fatigue on exclusive breastfeeding rates at discharge using the Visual Analog Scale to Evaluate Fatigue (VAS-F). Both mothers who delivered vaginally and by cesarean section took part in this study at no less than one day after delivery. One hundred percent of mothers in the study reported varying levels of fatigue postpartum, with 47% breastfeeding exclusively. An independent samples T-test compared fatigue levels in vaginal and cesarean births. Statistical significance was noted in that cesarean section mothers were more fatigued than those who gave birth vaginally (p=0.015). Findings from a chi squared test showed exclusive breastfeeding rates in women who gave birth vaginally higher than cesarean section (χ2=12.47,p<.01) suggesting exclusive breastfeeding rates were dependent on birth type. Further research needs to be completed to determine what education or strategies relative to postpartum fatigue need to be identified to diminish the effects of postpartum fatigue which could lead to improved exclusive breastfeeding rates.
ADAPTIVE CAPACITY AND STABILITY OF BREEDING POPULATIONS OF RED CLOVER UNDER CONDITIONS OF THE KIROV REGION
Authors: Onuchina Ol'ga , Korneva Irina
Published: December 2020

The results of the assessment of breeding populations of red clover according to the parameters of adaptive capacity and stability of the characteristic "yield of the dry mass" are presented. The experiments were laid on two types of soils, contrasting in the content of H+ ions и Al3+ ions. The meteorological conditions also significantly varied (drought in 2016 and over wetting in 2017). Parameters of adaptive capacity and stability of populations, environmental parameters as the base for the selection were counted according to A.V. Kilchevsky and L.V. Khotyleva method, regression coefficient of the genotype on the b1 environment was counted according to S.A. Eberhart and W.A. Russell method. Statistically high general adaptive capacity (GAAi = 3.10 t/ha), stability (σ2САСi = 0.64; Sgi = 6.68%) and the greatest breeding value (BVGi = 8.63) were identified in the tetraploid standard Kudesnik. Picked out, promising for adaptive breeding, diploid populations SGPA-53 and P-4/03, showing at an average GAAi (0.26 and –0.07 t/ha, respectively) the high stability (σ2CACi = 0.32–0.66; Sgi = 6.48–8.87%) and the breeding value (BVGi = 5.74–6.42). It is of interest to hybridize a low-productive (GAAi = –1.14 t/ha), but the most stable (σ2CACi = 0.08; Sgi = 3.62%, Kgi = 0.14) population P-15k. Correlation analysis revealed no significant relation between GAAi and stability parameters, which does not exclude the possibility of combining high productivity and environmental sustainability in one variety. A statistically high relation between the parameters Sgi and σ2CACi, Sgi and Kgi, (r = 0.86), bi and σ2CACi, bi and Kgi (r = 0.79) was established, indicating that these characteristics provide relatively close information on the population stability. The stress alumina background in 2017 and the medium acid ground (Sek – 40.88 and 35.33%; Pk – 0.37 and 0.32, respectively) were characterized by the highest differentiating ability and predictability.
Features of sheep border disease
Authors:   Kropotkin regional veterinary laboratory, Chernykh Oleg Yu. , Mishchenko Aleksey V. , Mishchenko Vladimir A. , Karaulov Anton K. , Petrova Olga N. ,   Federal Centre of Animal Healt, Krivonos Roman A. ,   Veterinary Department of Krasnodar region
Published: December 2020

Border sheep disease - viral congenital disease of sheep and goats that occurs during infection of pregnant ewes, characterized by lesions of the reproductive organs (abortions, stillbirths, infertility, birth of nonviable, mummified, undeveloped and ugly lambs) and organs of the immune system, growth retardation of newborn lambs, pathology of myelogenesis. The name of the disease was determined by the place of registration of the disease in 1959, in the border zone between England and Wales. Sheep border disease is considered to be one of the most common infections, causing great economic damage to cattle breeding worldwide. Infection of susceptible animals can proceed after the use of Pestivirus contaminated modified live virus vaccines. Border disease causative agent spreads with persistently infected animals. Border disease virus transmission can occur in mixed grazing of large horned cattle with infected sheep and goats and vice versa. Border disease virus was also isolated from deer, roe deer and other wild ruminants. 70-80% of lymphocytes in experimentally infected sheep contain the virus. Immunodeficiency state is detected in ruminants infected with border disease. The survival rate of offspring ranged from 59% to 88% during experimental infection with the border disease virus of pregnant ewes. The causative agent of border disease has negligible pathogenicity for pigs, but is highly pathogenic for large horned cattle, and cause potentially serious disorders of reproduction.
Clinical case of breast tumor relapse in domestic cat
Authors:   Omsk State Agrarian University named after P.A. Stolypin, Grechko Viktor V. , Bodrova Lyudmila F. , Ovchinnikov Dmitriy K. ,   Omsk State Agrarian University named after P.A. Stolypin
Published: December 2020

Domestic shorthair 10-year-old cat, not sterilized, not vaccinated, feeding from the table. We went to the clinic with breast cancer. General and special research methods were performed: blood analysis, x-ray examination of the lungs and abdominal ultrasound. Based on anamnesis and clinical examination, the diagnosis was made: a malignant breast tumor. The operation was performed. The operating material is sent for histological examination. Chemotherapy was prescribed. After the fi rst chemotherapy and monitoring of the animal's condition, it was necessary to perform a second unilateral mastoectomy of the remaining mammary glands, but the animal's owners refused to perform the operation. Chemotherapy was performed twice. Re-applied, after a year and a half with a sharp deterioration in the General condition and the appearance of a new tumor on the non-removed mammary glands. The owners refused the necessary treatment and decided to euthanize the cat. At the autopsy, breast neoplasms are presented as tubercles of various sizes. There are pronounced signs of inflammation, ulceration and necrosis foci. In the chest cavity, the lungs are enlarged, there were single and multiple formations of white and brown color, round shape of different diameters, dense consistency. There is a large number of metastases in the liver parenchyma. The organ is enlarged in size, dark brown in color, irregularly colored, with an uneven (bumpy) surface. In General, there are many dense nodes of a round-oval shape of white color, of various diameters. Histological examination of the tumor revealed foci of necrosis, atypical glandular complexes with frequently occurring mitosis figures. This structure indicates a low-grade breast adenocarcinoma. In the lungs, there is an expansion of the alveoli and bronchioles, thinning and rupture of the interalveolar partitions. There is a complex of tumor cells. In the liver, there is a lack of structural units of the liver, hepatocytes disperse chaotically, liver triads do not have a clear localization, atrophy and necrosis are expressed. Metastases in the liver, various forms. In a cat, a breast tumor interpreted as an adenocarcinoma had different biological behavior. At the initial diagnosis-adenocarcinoma of medium differentiation, and a year and a half later-low-grade adenocarcinoma.
Repurposing of Biologic and Targeted Synthetic Anti-Rheumatic Drugs in COVID-19 and Hyper-Inflammation: A Comprehensive Review of Available and Emerging Evidence at the Peak of the Pandemic
Authors: Cavalli Giulio , Farina Nicola , Campochiaro Corrado , De Luca Giacomo , Della-Torre Emanuel , Tomelleri Alessandro , Dagna Lorenzo
Published: December 2020

Coronavirus disease 2019 (COVID-19) is a condition caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe cases of COVID-19 result in acute respiratory distress syndrome and death. A detrimental, hyper-inflammatory immune response with excess release of cytokines is the main driver of disease development and of tissue damage in these patients. Thus, repurposing of biologic agents and other pharmacological inhibitors of cytokines used for the treatment of various inflammatory conditions emerged as a logical therapeutic strategy to quench inflammation and improve the clinical outcome of COVID-19 patients. Evaluated agents include the interleukin one receptor blocker anakinra, monoclonal antibodies inhibiting IL-6 tocilizumab and sarilumab, monoclonal antibodies inhibiting granulocyte-monocyte colony stimulating factor and tumor necrosis factor, and Janus kinase inhibitors. In this review, we discuss the efficacy and safety of these therapeutic options based on direct personal experience and on published evidence from observational studies and randomized clinical trials.
Field-Scale Soil Moisture Retrieval Using PALSAR-2 Polarimetric Decomposition and Machine Learning
Authors: Huang Xiaodong , Ziniti Beth , Cosh Michael H. , Reba Michele , Wang Jinfei , Torbick Nathan
Published: December 2020

Soil moisture is a key indicator to assess cropland drought and irrigation status as well as forecast production. Compared with the optical data which are obscured by the crop canopy cover, the Synthetic Aperture Radar (SAR) is an efficient tool to detect the surface soil moisture under the vegetation cover due to its strong penetration capability. This paper studies the soil moisture retrieval using the L-band polarimetric Phased Array-type L-band SAR 2 (PALSAR-2) data acquired over the study region in Arkansas in the United States. Both two-component model-based decomposition (SAR data alone) and machine learning (SAR + optical indices) methods are tested and compared in this paper. Validation using independent ground measurement shows that the both methods achieved a Root Mean Square Error (RMSE) of less than 10 (vol.%), while the machine learning methods outperform the model-based decomposition, achieving an RMSE of 7.70 (vol.%) and R2 of 0.60.
Development of Pea Breeding Lines with Resistance to Orobanche crenata Derived from Pea Landraces and Wild Pisum spp.
Authors: Rubiales Diego , Fondevilla Sara , Fernández-Aparicio Mónica
Published: December 2020

Pea (Pisum sativum) is an important grain legume worldwide whose cultivation is severely constrained by the root parasitic weed crenate broomrape (Orobanche crenata), which is widespread in the Mediterranean Basin and Middle East. No resistance is available in commercialized cultivars but some levels of incomplete resistance has been reported in pea landraces and Pisum spp. relatives. In this paper we report the development of a number of advanced pea breeding lines with resistance derived from wide crosses with resistant P. fulvum, P. sativum ssp. elatius, P. sativum ssp. syriacum, and with pea landraces, and critically discuss current progress and future perspectives on pea breeding for broomrape resistance. Resistance of breeding lines was confirmed over five field trials, showing markedly reduced broomrape over ground emergence, and in rhizotron experiments, showing either reduced tubercle formation or, in some of the lines, also hampered tubercle development that might grow slower or even become necrotic and die. Breeding lines performed well agronomically, having similar or mostly higher yields than the parental pea cv. Messire in environments with high broomrape incidence.
Effect of Neudesin Neurotrophic Factor on Differentiation of Bovine Preadipocytes and Myoblasts in a Co-Culture System
Authors: Li Anqi , Su Xiaotong , Wang Yaning , Cheng Gong , Zan Linsen , Wang Hongbao
Published: December 2020

In this study, we successfully established a co-culture system of bovine preadipocytes and myoblasts to explore the effect of exogenous addition of Neudesin neurotrophic factor (NENF) recombinant protein on the differentiation of adipocytes and myoblasts in co-culture. The optimal concentration of NENF recombinant protein was 100 pg/mL. NENF promoted the differentiation of bovine preadipocytes and inhibited the differentiation of bovine myoblasts when the cells were cultured separately. After adding NENF recombinant protein to the co-culture system, the accumulation of lipid droplets in bovine preadipocytes decreased, but the differentiation of bovine myoblasts did not change significantly. The results of real-time quantitative PCR (RT-qPCR) and Western blot showed that the expression levels of adipogenesis-related factors such as PPARγ, FABP4 and FASN were significantly down-regulated at the mRNA and protein levels in adipocytes, while myogenic marker genes such as MYOD1, MYOG and MYHC had no significant changes at the mRNA or protein levels in myoblasts. This differs from, and potentially conflicts with, the monoculture system, where NENF expression in each cell type changed with the cell microenvironment. Consequently, the molecular mechanism of marbling beef formation cannot be fully revealed using monocultures of adipocytes or myocytes.
Optimization of UV-C Processing of Donkey Milk: An Alternative to Pasteurization?
Authors: Papademas Photis , Mousikos Panagiotis , Aspri Maria
Published: December 2020

The effect of UV-C light technology on the inactivation of six foodborne pathogens inoculated in raw donkey milk was evaluated. Fresh raw donkey milk was artificially inoculated with the following foodborne pathogens—L. inoccua (NCTC 11288), S. aureus (NCTC 6571), B. cereus (NCTC 7464), Cronobacter sakazakii (NCTC 11467), E. coli (NCTC 9001), Salmonella enteritidis (NCTC 6676)—and then treated with UV-C doses of up to 1300 J/L. L. innocua was the most UV-C-resistant of the bacteria tested, requiring 1100 J/L for complete inactivation, while the rest of the bacteria tested was destructed in the range of 200–600 J/L. Results obtained from this study indicate that UV-C light technology has the potential to be used as a non-thermal processing method for the reduction of spoilage bacteria and foodborne pathogens that can be present in raw donkey milk.
Research on the Vibration Characteristics of a Track’s Structure Considering the Viscoelastic Properties of Recycled Composite Sleepers
Authors: Zhao Zhenhang , Gao Ying , Li Chenghui
Published: December 2020

In order to investigate the vibration characteristics of a composite sleeper-ballasted track and provide a basis for further popularization, a vehicle–track dynamic coupling model is established and the viscoelastic properties of the composite sleeper are considered. The power flow method is employed to reveal the power flow distribution characteristics of the composite sleeper. The results show that the viscoelastic properties of the composite sleeper have little influence on the rail power and have a greater influence on the power flow of the sleeper and ballast bed in some frequency ranges. The viscoelastic properties of the composite sleeper can effectively improve the calculation accuracy of the track structure’s power flow. Compared with the type-III pre-stressed concrete sleepers widely used in China, composite sleepers consume more energy in the vibration process due to their own physical characteristics, which reduces the power flow transmitted downward and relieves vibration on the ballast bed, especially in the ranges of 80–125 Hz and 250–400 Hz. The temperature change mainly affects the power flow of the composite sleeper in the frequency range above 50 Hz. As the temperature increases, the modulus of the composite sleeper decreases and the vibration reduction effect of the ballast bed is improved.
Eggplant Fruit (Solanum melongena L.) and Bio-Residues as a Source of Nutrients, Bioactive Compounds, and Food Colorants, Using Innovative Food Technologies
Authors: Silva Gabriel F. Pantuzza , Pereira Eliana , Melgar Bruno , Stojković Dejan , Sokovic Marina , Calhelha Ricardo C. , Pereira Carla , Abreu Rui M. V. , Ferreira Isabel C. F. R. , Barros Lillian
Published: December 2020

Consumers are very concerned with following a healthy diet, along with some precautions that may influence environmental impact. Solanum melongena L. is one of the most consumed vegetables due to its excellent nutritional value and antioxidant action. Associated with its high consumption, considerable amounts of agro-food wastes are produced. This work targets the valorization of this matrix, through the use of its bio-residues to study the obtention of coloring pigments, applying innovative technologies. Its nutritional value, chemical composition, and bioactive potential were evaluated, and the ultrasound-assisted extraction to obtain coloring pigments of high industrial interest was optimized. Considering the results, low contents of fat and carbohydrates and energy value were evident, as well as the presence of compounds of interest (free sugars, organic acids, unsaturated fatty acids, and phenolic acids). In addition, the antioxidant and antimicrobial potential was detected. Response surface methodology was performed to optimize the extraction of natural pigments, showing a concentration of 11.9 mg/g of anthocyanins/g of extract, applying optimal conditions of time, solvent, and solid/liquid ratio of 0.5 min, 68.2% (v/v) and 5 g/L, respectively. S. melongena proved to be a good source of bioactive compounds and natural pigments, which can generate great interest in the food industry.
Synthesis of Silver Nanoparticles with Gemini Surfactants as Efficient Capping and Stabilizing Agents
Authors: Brycki Bogumił , Szulc Adrianna , Babkova Mariia
Published: December 2020

The scientific community has paid special attention to silver nanoparticles (AgNPs) in recent years due to their huge technological capacities, particularly in biomedical applications, such as antimicrobials, drug-delivery carriers, device coatings, imaging probes, diagnostic, and optoelectronic platforms. The most popular method of obtaining silver nanoparticles as a colloidal dispersion in aqueous solution is chemical reduction. The choice of the capping agent is particularly important in order to obtain the desired size distribution, shape, and dispersion rate of AgNPs. Gemini alkylammonium salts are named as multifunctional surfactants, and possess a wide variety of applications, which include their use as capping agents for metal nanoparticles synthesis. Because of the high antimicrobial activity of gemini surfactants, AgNPs stabilized by this kind of surfactant may possess unique and strengthened biocidal properties. The present paper presents the synthesis of AgNPs stabilized by gemini surfactants with hexadecyl substituent and variable structure of spacer, obtained via ecofriendly synthesis. UV-Vis spectroscopy and dynamic light scattering were used as analyzing tools in order to confirm physicochemical characterization of the AgNPs (characteristic UV-Vis bands, hydrodynamic diameter of NPs, polydispersity index (PDI)).
Fluoride Exposure and the Effect of Tobacco Smoking on Urinary Fluoride Levels in Primary Aluminum Workers
Authors: Schwarz Marián , Salva Jozef , Vanek Miroslav , Rasulov Oqil , Darmová Ivana
Published: December 2020

Workers in primary aluminum smelter are exposed to fluoride from cryolite (Na3AlF6) used in the electrolysis process. Post-shift urinary fluoride is considered as an appropriate index for examination of fluoride exposure. The objective of the study was to investigate the exposure to fluoride in primary aluminum smelter in Žiar nad Hronom (Slovakia) during three consecutive two-year periods between 2012 and 2018. The relationship between fluoride exposure in the occupational environment, tobacco smoking, and pre- and post-shift urinary fluoride concentration was investigated in 76 male workers in the ages from 21 to 60 years. Workers were monitored by personal fluoride sampling equipment. Their urinary samples were collected prior to the start and at the end of an eight-hour shift. Fluoride content in urine samples was analyzed by potentiometric ion-selective electrode and expressed as weight ratio of fluoride content to creatinine. The Mean ± SD particulate fluoride concentration in occupational air was 0.966 ± 1.658 mg/m3 and gas-phase fluoride concentration was 0.327 ± 0.809 mg/m3. Mean urinary fluoride concentration of all workers was significantly higher (p < 0.001) after the eight-hour shift. Smokers tended to have a higher post-shift mean urinary fluoride concentration than non-smokers, but this difference was not statistically significant (p = 0.11). The difference between these two groups of workers was also not statistically significant (p = 0.62) before the shift. Therefore, according to results, smoking caused no statistically significant difference in urinary fluoride levels between the group of smokers and group of non-smokers in primary aluminum workers.
Evaluating the Impact of Drone Signaling in Crosswalk Scenario
Authors: Bouassida Sana , Neji Najett , Nouvelière Lydie , Neji Jamel
Published: December 2020

The characteristic pillars of a city are its economy, its mobility, its environment, its inhabitants, its way of life, and its organization. Since 1980, the concept of smart city generally consists of optimizing costs, organization, and the well-being of inhabitants. The idea is to develop means and solutions capable of meeting the needs of the population, while preserving resources and the environment. Owing to their little size, their flexibility, and their low cost, Unmanned Aerial Vehicles (UAV) are today used in a huge number of daily life applications. UAV use cases can be classified into three categories: data covering (like surveillance and event covering), data relaying (like delivery and emergency services), and data dissemination (like cartography and precise agriculture). In addition, the interest to Cooperative Intelligent Transportation Systems (C-ITS) has risen in these recent years, especially in the context of smart cities. In such systems, both drivers and traffic managers share the information and cooperate to coordinate their actions to ensure safety, traffic efficiency, and environment preservation. In this work, we aimed at introducing a UAV in a use case that is likely to happen in C-ITS. A conflict is considered involving a car and a pedestrian. A UAV observes from the top of the scene and will play the role of the situation controller, the information collector, and the assignment of the instructions to the car driver in case of a harmful situation to avoid car-pedestrian collision. To this end, we highlight interactions between the UAV and the car vehicle (U2V communication), as well as between the UAV and infrastructure (U2I communication). Hence, the benefit of using UAV is emphasized to reduce accident gravity rate, braking distance, energy consumption, and occasional visibility reduction.
Short Term Electric Load Forecasting Based on Data Transformation and Statistical Machine Learning
Authors: Andriopoulos Nikos , Magklaras Aristeidis , Birbas Alexios , Papalexopoulos Alex , Valouxis Christos , Daskalaki Sophia , Birbas Michael , Housos Efthymios , Papaioannou George P.
Published: December 2020

The continuous penetration of renewable energy resources (RES) into the energy mix and the transition of the traditional electric grid towards a more intelligent, flexible and interactive system, has brought electrical load forecasting to the foreground of smart grid planning and operation. Predicting the electric load is a challenging task due to its high volatility and uncertainty, either when it refers to the distribution system or to a single household. In this paper, a novel methodology is introduced which leverages the advantages of the state-of-the-art deep learning algorithms and specifically the Convolution Neural Nets (CNN). The main feature of the proposed methodology is the exploitation of the statistical properties of each time series dataset, so as to optimize the hyper-parameters of the neural network and in addition transform the given dataset into a form that allows maximum exploitation of the CNN algorithm’s advantages. The proposed algorithm is compared with the LSTM (Long Short Term Memory) technique which is the state of the art solution for electric load forecasting. The evaluation of the algorithms was conducted by employing three open-source, publicly available datasets. The experimental results show strong evidence of the effectiveness of the proposed methodology.
Preparatory Experiments Regarding Human Brain Perception and Reasoning of Image Complexity for Synthetic Color Fractal and Natural Texture Images via EEG
Authors: Nicolae Irina E. , Ivanovici Mihai
Published: December 2020

Texture plays an important role in computer vision in expressing the characteristics of a surface. Texture complexity evaluation is important for relying not only on the mathematical properties of the digital image, but also on human perception. Human subjective perception verbally expressed is relative in time, since it can be influenced by a variety of internal or external factors, such as: Mood, tiredness, stress, noise surroundings, and so on, while closely capturing the thought processes would be more straightforward to human reasoning and perception. With the long-term goal of designing more reliable measures of perception which relate to the internal human neural processes taking place when an image is perceived, we firstly performed an electroencephalography experiment with eight healthy participants during color textural perception of natural and fractal images followed by reasoning on their complexity degree, against single color reference images. Aiming at more practical applications for easy use, we tested this entire setting with a WiFi 6 channels electroencephalography (EEG) system. The EEG responses are investigated in the temporal, spectral and spatial domains in order to assess human texture complexity perception, in comparison with both textural types. As an objective reference, the properties of the color textural images are expressed by two common image complexity metrics: Color entropy and color fractal dimension. We observed in the temporal domain, higher Event Related Potentials (ERPs) for fractal image perception, followed by the natural and one color images perception. We report good discriminations between perceptions in the parietal area over time and differences in the temporal area regarding the frequency domain, having good classification performance.
Dynamic Response Analysis of Composite Tether Structure to Airborne Wind Energy System under Impulsive Load
Authors: Ha Kwangtae
Published: December 2020

The tether structure plays the role of transferring the traction force of an airborne wind energy system (AWES) to the fixed or mobile ground system with less motion and maintains the flying airborne system as a critical component. The implementation of a geometrically tailored tether design in an AWES could avoid unwanted snap-through failure, which can be take place in a conventional tether structure under impulsive loading. This concept relies on the redundant load path of the composite structure composed of tailored length and strength. In this study, the dynamic response of this composite tether structure to airborne wind energy systems, such as a kite wind power system, was analytically investigated. Also, for very long tether applications, an approximate model of the tether response was developed, which resulted in a dramatic reduction of computational efforts while preserving the accuracy quite well compared to the exact solution.