bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of diet and lifestyle in skin care and skin diseases
Authors: Krithi Neerpady K  , Shripathi Acharya
Published: January 2024

Introduction: Skin is of crucial importance in the human system. There are numerous factors that affect its appearance and function leading to many skin issues. Aim: To give information about the role of the diet in maintaining healthy skin and the usage of knowledge in everyday practice, a detailed analysis of available literature is performed on the impact and mechanisms of various food ingredients on the role and appearance of skin through understanding the Nidana of Kushta. Data: The data on the nutrients that affect healthy skin are obtained: The quality, health and beauty of the skin are affected by various vitamins, minerals, proteins, as well as by other nutrients. Some foods make skin shiny and healthy, but there is also bad diet for skin, as well as foods with harmful effects, depending on skin type. Discussion: It is of crucial importance to protect skin from negative factors. In order to provide normal functioning of the skin it is necessary to incorporate various foods of animal or plant origin, taking in consideration skin type as well. Conclusion: It is clear why full attention should be paid to skin, its health, functions, and appearance. Adequate diet is of prime importance, with usage of Pathyahara and vihara and paying attention to possible beneficial effects of certain foods, adjusted to the skin type. This should be applied in everyday practice in working with patients.
Amshansha Kalpana : A Quantitative Interpretation of the properties of Doshas in sickness
Authors: Jyotsana Choudhary  , Munna Lal  , Ishwar Dutt Sharma  , Pankaj Marolia  , Man Mohan Sharma
Published: January 2024

The love of truth is philosophy. Science is the process of doing experiments to find the truth. The systematized knowledge and practical wisdom of Ayurveda are combined to form the science of life. Three fundamental energies or functional principles, which are found throughout the human body, are created when the five great elements - space, air, fire, water, and earth combine. Vata, Pitta, and Kapha are the three Doshas that are found in every cell, tissue, and organ. A balanced state of Doshas promotes health; when it is not, it promotes sickness. The term Amshansha Kalpana refers to the analysis of Doshas in relation to Guna participation. The diagnosis and selection of medical conditions are the goals of analysis in this subject. No Dravya, according to Acharya Vagbhatta, is composed of a single Rasa, and similarly, no Roga is brought about by a single Doshas. The ways in which Doshaja and Dushyas are combined in varying quantities determine how a sickness presents itself. Here is an illustration of a sickness.
Management of Indralupta (Alopecia Areata) - A Case Study
Authors: Syed Rasool Sufiyan  , Veerayya R. Hiremath  , Shashikala K.  , Gururaj N  , Raju S.N.
Published: January 2024

Indralupta is one of the Urdhwajatrugata Vyadhi characterized by the patchy hair loss over hair-bearing skin that includes scalp and beard. According to Sushruta Acharya, Indralupta is due to the vitiated pitta in association with vitiated Vata causing the falling of hairs from the scalp and vitiated Rakta and Kapha block the orifices of the hair follicles which restricts the growth of new hair. Alopecia areata is autoimmune disease presented as nonscarring, circumscribed, smooth patch of hair loss, management is by the intralesional and topical corticosteroids. Shodhana (Raktamokshana) and Shamana Chikitsa is advised for the Indralupta in ayurveda classics. In this present case study 17 years old male patient is treated with Pracchanna Karma (Raktamokshana) followed by Maricha Lepa along with internal medicine. The therapy has shown a remarkable improvement in the signs of Indralupta. The patient obtained considerable relief from the symptoms through the therapy. The treatment proved to be easy, economical, highly effective with in short duration.
An Open Label Single Arm Clinical Study of Asthishrinkhala Ghrita Matrabasti and Asthishrinkhala Vati in Janusandhigatavata (Osteo-arthritis of knee)
Authors: Niveditha M N  , Vasantha B  , Muttappa Totad  , Adarsh Kallimath
Published: January 2024

Background: Osteoarthritis is the most common type of arthritis occurring in weight bearing joints like hip and knee. Main presenting symptoms are pain and functional restriction. With advancement in working pattern and age factor, it has become prime cause for aggravation of Vata Dosha, which does Dhatu Kshaya and Bala Kshaya leading to Sandhigatavata. Due to all these factors and being a Marma sthana, the person will be incapacitated from doing his day-to-day activities. Aims and objectives: To clinically evaluate the combined effectiveness of Asthishrinkhala Ghrita Matrabasti and Asthishrinkhala Vati in Janusandhigatavata. Methodology: In the present study, 34 patients of Janusandhigatavata fulfilling diagnostic criteria were given Asthishrinkhala Ghrita Matrabasti for 7days and Asthishrinkhala Vati for 21 days. Assessment were done using Visual Analogue Scale (VAS) for Pain, Ritchie articular index for assessment of tenderness, Swelling and crepitus based on numerical Scoring, Movement of joints measurement is done with Goniometer and physical functions assessed through WOMAC- Index for Osteoarthritis. Results: Data was analyzed using appropriate statistical test. Significant results (p<0.05) were found in all the cardinal symptoms- Vata Poornadruti Sparsha Shotha, Shula on Prasarana and Akunchana, Atopa and Stabdhata in Janusandhi. Conclusion: Asthishrinkhala Ghrita Matrabasti and Asthishrinkhala Vati is effective in management in Janusandhigatavata.
Effect of Panchatikta Ghrita Guggul and Mahamanjishthadi Kwath along with Virechan Karma in the management of Ek Kushtha (Plaque Psoriasis) : A Case Report
Authors: Saraf Shraddha , Swati Nagpal  , Shwetal Shivhare  , Vivek Sharma
Published: January 2024

Background: Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. About 2% of the world population and 0.44-2.8% of the Indian population were affected by psoriasis in 2016-2017. Plaque psoriasis is the most common type of psoriasis that manifests as red scaly patches with white scales affecting body areas, including the scalp, elbows, knees, trunk, and buttocks. The Ayurvedic diagnosis is considered as Ekakushtha which is a Vata Kapha predominant Kshudrakushtha. Objective: The present study was intended to assess the efficacy of Virechan Karma as Shodhan procedure along with Panchatikta Ghrita Guggul and Mahamanjishthadi Kwath as Shaman drug in Ek Kushtha (psoriasis). Materials and Methods: Here an effort was made to treat a 21 years old male diagnosed case of Plaque Psoriasis since 1 year. He presents with complaints of red scaly patches with white scales on upper limbs, lower limbs and trunk with itching and burning. After a thorough examination, an Ayurvedic treatment plan was designed in the form of Panchakarma (Virechan Karma) and oral medication (Panchatikta Ghrita Guggul 250 mg twice and Mahamanjishthadi Kwath 10 ml twice daily). As the principle of treatment of all types of Kushtha is Sanshodhana along with Sanshamana drugs. In this study initially Virechana Karma was performed. Result: After Sanshodhana, Sanshamana drugs were given for 4 months, the symptoms such as itching, burning, eruption, scaly patches gradually decreased. PASI (Psoriasis area severity index) score was taken for assessment parameter showed significant improvement. The skin lesions of the patient was calculated by PASI score before starting the treatment was found to be 29.9 which decreased to 3.5 after 4 months. Conclusion: This case report showed that combined Ayurvedic modalities resulted in great improvement in overall condition of the patient and clinically safe and effective in the management of Ekkushtha (psoriasis).
A clinical study on the effect of Lodhradi Kashaya on Madhumeha with special reference to Diabetes Mellitus (Type-2)
Authors: Nihar Ranjan Mahanta  , Sahoo Preetimayee
Published: January 2024

Introduction: Ayurveda describes Prameha as a disease entity which involves a number of diseases with various physical and chemical changes in urine. Madhumeha is included under Vatik Prameha where astringency is associated with sweetness in urine. The manifestation of metabolic abnormality as well as urinary tract pathology are included in two symptoms: Prabhuta Mutrata (excessive urination) and Avila Mutrata (urine turbidity). Sedentary life style, indulgence of Kapha-meda Vardhaka Ahara, avoidance of regular exercise, day sleep indicate Santarpanajanya origin of the disease. Methods: Lodhradi Kashaya with Lodhra, Musta, Katphal and Haritaki as described in Vasavarajeeyam is taken for this clinical study on 60 patients and its efficacy was compared with a standard drug metformin. Results: During the study it was found that both Lodhradi Kashaya and Metformin provided significant result in improving Signs and Symptoms like polyuria, turbid urination, Polydipsia, polyphagia, burning sensation, numbness, weakness, lassitude, pruritus, muscle cramps, and increased sweating. The test of significance shows that both the trial drug and control drug were highly significant at 0.1% level with p-value <0.001 to improve glycosuria, FBS, PPBS and HbA1c in patients. Comparative analysis of the effectiveness of Lodhradi Kashaya and metformin w.r.t. objective sign and symptoms showed that both the treatments are almost equally effective to improve glycosuria, FBS, PPBS and HbA1c while Lodhradi Kashaya gives better clinical improvement than metformin in long term use in Diabetes. Lodhradi Kashaya is an efficient anti diabetic drug.
Clinical evaluation of Nirabhishankita Basti Karma administered by three piecemeal Putak - A Pilot Clinical Study
Authors: Harsha Gupta  , Preeti Chaturvedi
Published: January 2024

Background: Pain has globally become an attention problem which causes discomfort by affecting the body as well as the mind. Pain (Ruja) is the cardinal feature of most of the musculoskeletal disorders and it can be affect the quality of life. In Ayurveda all types of pain are under the umbrella of Vata which is the prime for generating and spreading the pain. Basti is given more importance because it directly pacifies the vitiated Vata Dosha. Aim and Objective: To evaluate the efficacy of Nirabhisankita Basti Karma administered by three piecemeal Putak. Materials and Methods: Randomly selected 5 patients were examined on the ground of Astavidha Pariksha (eight-fold examination) and specially prepared data research questionnaire. Selected subjects were administered with three piecemeal Putak Basti for 3 days and it was followed up of 15 days. Assessment was done through various variables like pain, stiffness, numbness, tingling, and gait. Results: The study showed that Nirabhisankit Basti produced an extremely significant improvement in pain and gait with 85.7 & 90 percentage reliefs while very significant in stiffness, numbness and tingling. Conclusion: Nirabhisankit Basti is found to be effective in musculoskeletal pain.
Development of Foetal Body Parts as per Garbhaavakraanti Shaareera - An Ayurvedic Perspective
Authors: Prabhu Rohit Ramesh  , Ranjith Kumar Shetty  , Sri Nagesh K.A
Published: January 2024

The conception and development of a healthy offspring have been a paramount concern for humanity throughout history. This concern is deeply rooted in various cultures and traditions, and Ayurveda, an ancient Indian system of medicine, offers a holistic perspective on factors that influence the growth and development of a fetus. Ayurveda underscores several critical factors to ensure the birth of a normal and healthy progeny. These factors include "Garbha Saamagri," which pertains to the quality of reproductive materials, emphasizing the significance of the parents' health at the time of conception. "Daurhruda" relates to the timing and season of conception, asserting that environmental factors play a role in the child's health. The "Pitrujadi Six Factors" encompass inherited attributes from both parents, stressing the importance of genetic compatibility between partners. Additionally, Ayurveda places a strong emphasis on the lifestyle and nutrition of the pregnant woman, her emotional well-being, and the regimen during her menstrual cycle. All these factors are believed to influence the child's constitution and overall health. "Svabhava" considers the inherent nature and constitution of both parents, which can affect the physical and mental attributes of the child. It is important to note that Ayurveda offers a holistic and ancient perspective on these factors. In conclusion, Ayurveda provides a comprehensive framework for understanding the factors that influence fetal growth and development.
Study of Nidra w.s.r. to Bhutadhatri Nidra
Authors: Puspa Priyadarshani  , Vijay Shankar Pandey
Published: January 2024

To keep the balance of the body, there is description of three Upastambha. The three Upasthambha are Ahara, Nidra and Bramhacharya, which glorifies Nidra as an essential factor for a healthy life. Nidra (sleep) is very crucial for day -to- day life and also for physical & mental wellness of human being. A multi-dimensional approach to Nidra is found in Ayurvedic literature where many Acharyas have given their precious pronouncements and directives regarding sleep. In Samhitas, Nidra and Swapna are regarded as equivalent in many places but Vata and Raja collectively causes Swapna which is termed as Swapna Darshan (dreaming). Qualitative and quantitative sleep that occurs in proper time is appreciated as “Bhutadhatri Nidra” in Ayurveda. It rejuvenates and re-energizes body as well as mind while improper sleep can give rise to harmful effects on health. This article is designed to provide a comprehensive review of concepts, mechanism & effect of Nidra on human body by collecting the facts and information based on Ayurveda classics. In the era of modernization, sedentary life-style and desk bound professions; people are more prone to diseases like diabetes mellitus, obesity, hypertension, heart diseases etc. due to their faulty sleeping habits. Nidranasha (insomnia), Atinidra (hypersomnia), Akala Nidra (untimely sleeping habits), Diva Swapna (day sleep/ narcolepsy), Ratri Jagaran (awakening at night) etc. deteriorate their overall health. In ancient times Yogis like Arjun and Laxman had conquered sleep and achieved their goal without facing any noticeable health issues. In contemporary world the concept of Yoga Nidra is brought into vogue due to its beneficial effects on human health. Hence it is always necessary to understand the concept of Nidra, factors affecting it and its role in sustaining a healthy life.
KARAKTERISTIK FISIKOKIMIA ES KRIM DENGAN PENAMBAHAN BUBUK DAUN KERSEN (Muntingia calabura L.)
Authors: Satar Ibdal , Nistia Winne Ayu
Published: January 2024

Es krim termasuk produk pangan semi padat, memiliki tekstur lembut, rasa yang enak dan manis sehingga disukai oleh banyak orang. Namun, pada umumnya es krim masih rendah nilai aktivitas antioksidan. Oleh sebab itu, diperlukan pendekatan yang sesuai untuk meningkatkan aktivitas antioksidan es krim agar menjadi produk yang bernilai fungsional. Daun kersen kaya dengan kandungan komponen-komponen bioaktif seperti flavonoid, tanin, triterpen, saponin, dan polifenol. Bubuk daun kersen (BDK) diyakini dapat diaplikasikan sebagai bahan tambahan untuk meningkatkan aktivitas antioksidan pada es krim. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan BDK terhadap sifat fisikokimia es krim. Rancangan Acak Lengkap (RAL) satu faktor penambahan BDK telah digunakan dalam penelitian ini. Beberapa komposisi BDK yang digunakan adalah 0%(F0), 0,5%(F1), 1%(F2), 1,5%(F3), dan 2%(F4). Karakteristik fisikokimia es krim yang dievaluasi antara lain overrun, waktu leleh, komposisi air, komposisi protein total, komposisi gula total, komposisi flavonoid, dan aktivitas antioksidan (IC50). Karakteristik fisikokimia es krim dengan penambahan BDK menunjukkan nilai overrun 50,27-40,73%, waktu leleh 27,52-36,13 menit/g, kadar air 64,82-62,79%, kadar lemak 5,88-4,74%, kadar protein total 2,00-2,70%, kadar gula total 29,63-33,71%, kadar flavonoid 0,01-0,08%, dan aktivitas antioksidan IC50 71,16-30,02 ppm. Secara keseluruhan, karakteristik fisikokimia es krim dengan penambahan BDK menunjukkan perbedaan yang siginifikan (p<0,05).
KINETIKA PENGERINGAN VAKUM DAN KARAKTERISTIK FISIKOKIMIA IRISAN MANGGA MANALAGI (Mangifera Indica L.)
Authors: Hawa La Choviya , Melindasari Alfida Alviolita , Al Riza Dimas Firmanda , Efendi Mohamad
Published: January 2024

Mangga Manalagi memiliki kandungan gizi serta kadar air yang tinggi, sehingga mudah mengalami perubahan fisik yang ditandai dengan adanya reaksi enzimatik. Oleh karena itu, perlu teknologi pascapanen untuk memperpanjang umur simpan. Teknologi pengeringan vakum merupakan salah satu teknologi yang dapat menjaga kualitas hasil pengeringan, yang lebih baik dibandingkan dengan teknologi pengeringan konvensional. Tujuan penelitian ini untuk menentukan kinetika pengeringan dan perubahan fisikokimia selama pengeringan dengan menggunakan teknologi vakum pada irisan mangga Manalagi. Pengeringan dilakukan menggunakan variasi tekanan vakum (200, 300, dan 400 mbar) dan pra-perlakuan (larutan asam sitrat, asam askorbat, dan air lemon yang dikombinasikan dengan larutan kalsium laktat). Terjadi penurunan kadar air seiring lama pengeringan vakum. Laju pengeringan rata-rata dengan rentang 0,07-0,08%bb/menit. Kinetika pengeringan diprediksi dengan menggunakan tiga model semi empiris dan didapatkan model Midilli sebagai model terbaik berdasarkan uji ketepatan. Berdasarkan ANOVA dua arah menunjukkan bahwa variasi pra-perlakuan dan tekanan memberikan pengaruh nyata terhadap parameter kadar air, total padatan terlarut, kekerasan, dan warna. Nilai yang didapatkan hingga akhir proses pengeringan secara berturut-turut adalah 19,03-25,16%bb; 21,41-31,24%˚Brix; 9,59-20,82 kgf; L* 44,92-69,99; a* 6,41-12,80; dan b* 27,43-43,17.
Estudo de parâmetros mecânicos de dois solos arenosos estabilizados com cimento
Authors: Pereira L. F. M. , Branco F. G. , Oliveira P.V. , Andrade P.S.
Published: January 2024

O solo é o material natural de construção mais abundante na natureza e detém muitas vezes propriedades excelentes que o tornam apetecível enquanto material de construção: é resistente, esteticamente agradável, plástico, e tem um baixo custo. Sendo uma das metas primordiais de uma obra a racionalização de custos, a utilização dos solos existentes no local é, desde há muito tempo, um objetivo apetecível. No entanto, nem todos os solos, devido a fatores tais como a granulometria, a composição mineralógica ou a presença de matéria orgânica, se comportam de modo aceitável em termos mecânicos. A adição de cimento Portland modifica as propriedades dos solos através de processos físico-químicos entre os grãos do solo e o cimento, promovendo a formação de um esqueleto que cimenta e envolve os grãos. Neste trabalho estudou-se a melhoria de dois solos através da estabilização com cimento Portland. Os resultados obtidos permitiram concluir que o comportamento mecânico melhorou com o tempo de cura dos provetes e com o aumento do teor de ligante. Foi ainda possível definir uma razão entre a resistência à compressão diametral e a resistência à compressão uniaxial simples. Determinou-se que existe um teor em água “ótimo” que permite obter um comportamento mecânico mais competente. Concluiu-se que existe uma razão água/cimento (w/c) “ótima” para cada teor de ligante, e que esta tende a diminuir com o aumento deste último.
Incorporação de lamas provenientes do corte de rochas ornamentais em materiais cimentícios
Authors: Moreira O. , Malheiro R. , Jesus C. , Camões A. , Ribeiro M.J.
Published: January 2024

O desenvolvimento mundial impulsiona a procura por cimento e os desafios ambientais associados à sua fabricação preocupam os investigadores. O setor de cimento é o terceiro maior consumidor industrial de energia e o segundo maior emissor de CO2. Neste sentido, algumas medidas têm sido implementadas. Para além da redução da relação clínquer/cimento, a redução do consumo de cimento através da utilização de Materiais Cimentícios Suplementares em substituição parcial do cimento é uma estratégia eficiente e atual. O uso de resíduos industriais como, por exemplo, as lamas provenientes do corte de rochas ornamentais, tem sido uma aposta que favorece, também, a economia circular. Neste sentido, foi desenvolvida uma pesquisa experimental com o objetivo de avaliar o comportamento de argamassas cuja composição utiliza lamas provenientes do corte de rochas ornamentais produzidas em Portugal, nomeadamente, travertino, gabro, granada e basalto. Foram estudadas propriedades das argamassas no estado fresco e endurecido após 28 e 90 dias de cura. O índice de atividade pozolânica foi determinado. Os resultados sugerem um desempenho satisfatório face às argamassas de referência. As lamas estudadas promovem a economia circular e têm potencial para se apresentar como substituto parcial do cimento na produção de materiais cimentícios com utilizações específicas.
Psychological effects of the COVID-19 pandemic and nurses' coping mechanisms: A correlational study
Authors:   College of Nursing, University of Hail, Hail, Saudi Arabia, Cabansag Dolores I. , Alshammari Farhan ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Pangket Petelyne ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Borja Ma. Venus F. ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Villagracia Hazel ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Majid Fredezwinda ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Alreshidi Maha ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Rosaupan Joyce R. ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Pineda Ma. Nieva ,   College of Nursing, University of Hail, Hail, Saudi Arabia, Briones Marifa ,   College of Nursing, University of Hail, Hail, Saudi Arabia
Published: January 2024

Many nurses have suffered mental health problems as a result of the COVID-19 pandemic. Nurses' workload and stress have increased as they care for infected patients and their families. Lockdowns and quarantines have exacerbated the problem, causing psychological distress. To determine the psychological impact of COVID-19 on hospital nurses and their coping mechanisms. A cross-sectional design and convenience sampling study using the original impact event scale (IES) and stress scale (SS) in the analysis. A total of 241 nurses from government and private hospitals in the Hail region of Saudi Arabia participated voluntarily. Most respondents were female (96.7%), 31-40 years old (48.1%), married (61.8%), dominant participants were Filipino nurses (47.7%), the majority worked in private hospitals (54.8%), and those with more than ten years of hospital experience were the largest group (39.4%). COVID-19 had a significant psychological impact on 81.33% of the respondents and a severe impact on 9.5%. The respondents' coping mechanisms are adaptive (MS=37.56, STD=4.02) in terms of complete problem-solving (MS=14.76, STD=2.93) and symptom management (MS=8.93, STD=1.90). There is a significant relationship between psychological impact and coping mechanisms, specifically in terms of social support (p-value-0.000) and symptom management (p-value-0.047). Healthcare institutions should prioritize programs to support nurses, especially during outbreaks, as this can improve patient outcomes and care for all. Healthcare workers need social support and adaptability training from policymakers to cope with stress and uncertainty.
The use of IoT in Health Care System: A Perspective
Authors: Poorva Sanjay Sabnis  , Snehal Shewale
Published: January 2024

Health care becomes one of serious issues all over the planet, particularly in maturing individuals, where it costs hugewellbeing spreads and assets. The IoT can possibly further develop wellbeing and prosperity through more prominenteffectiveness and further developed care in existing medical services settings, by empowering more noteworthy utilization ofremote telehealth arrangement, and empowering people to screen their own wellbeing everyday, further develop solace andbetter oversee conditions, analyze ailments all the more rapidly and advance therapy systems. Expanding market interest forsuperior execution and convenient processing gadgets requires energy proficient gadgets. Whenever an organization ofgadgets is thought of, as on account of the Internet of Things, it is vital to consider low power plan at the sensor/actuator levelas well as in the sensor organization. Human body correspondence has shown to be a proficient method of correspondence forclose to handle body sensor network applications. The recent fads in medical services are bit by bit advancing with theassistance of IoT which might make us more wellbeing cognizant. As far as deterrent consideration, IoT wellness gadgetslike Fit pieces, and development sensors currently incorporated into many new advanced cells, empower numerous people toscreen and track themselves, which for the most part advances better ways of life. This paper audits the ideas, applicationsand different existing advances for medical care.
Acknowledgement to Reviewers of OBM Geriatrics in 2023
Authors: Editorial Office OBM Geriatrics
Published: January 2024

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the service Publons (https://publons.com) to receive recognition. Of course, in these initiatives we are careful not to compromise reviewer confidentiality. Many reviewers see their work as a voluntary and often unseen part of their role as researchers. We are grateful to the time reviewers donate to our journals and the contribution they make.
Comparing Self-Reported Running Distance and Pace With a Commercial Fitness Watch Data: Reliability Study
Authors: Bullock Garrett , Stocks Joanne , Feakins Benjamin , Alizadeh Zahra , Arundale Amelia , Kluzek Stefan
Published: January 2024

Background

There is substantial evidence exploring the reliability of running distance self-reporting and GPS wearable technology, but there are currently no studies investigating the reliability of participant self-reporting in comparison to GPS wearable technology. There is also a critical sports science and medical research gap due to a paucity of reliability studies assessing self-reported running pace.

Objective

The purpose of this study was to assess the reliability of weekly self-reported running distance and pace compared to a commercial GPS fitness watch, stratified by sex and age. These data will give clinicians and sports researchers insights into the reliability of runners’ self-reported pace, which may improve training designs and rehabilitation prescriptions.

Methods

A prospective study of recreational runners was performed. Weekly running distance and average running pace were captured through self-report and a fitness watch. Baseline characteristics collected included age and sex. Intraclass correlational coefficients were calculated for weekly running distance and running pace for self-report and watch data. Bland-Altman plots assessed any systemic measurement error. Analyses were then stratified by sex and age.

Results

Younger runners reported improved weekly distance reliability (median 0.93, IQR 0.92-0.94). All ages demonstrated similar running pace reliability. Results exhibited no discernable systematic bias.

Conclusions

Weekly self-report demonstrated good reliability for running distance and moderate reliability for running pace in comparison to the watch data. Similar reliability was observed for male and female participants. Younger runners demonstrated improved running distance reliability, but all age groups exhibited similar pace reliability. Running pace potentially should be monitored through technological means to increase precision.
The COSMOS Registry of CytoSorb Hemoadsorption Therapy in Critically Ill Patients: Protocol for an International, Prospective Registry (Preprint)
Authors: Taccone Fabio Silvio , Brunkhorst Frank Martin , Bottari Gabriella , Hidalgo Jorge , Kribben Andreas , Teboul Jean-Louis , Tomescu Dana , Klaus Teresa , Scheier Joerg , Deliargyris Efthymios , Ferrer Ricard
Published: January 2024

BACKGROUND

Extracorporeal blood purification with CytoSorb has been increasingly used as an adjunctive therapy in several hyperinflammatory critical care conditions, as well as to remove elevated levels of myoglobin or bilirubin in patients with rhabdomyolysis or liver failure. Despite the increasing worldwide use of hemoadsorption, data from large international multicenter studies are still lacking.

OBJECTIVE

The COSMOS (CytoSorb Treatment Of Critically Ill Patients) registry is a company-sponsored registry by CytoSorbents Corporation and CytoSorbents Medical Inc. and will provide a data repository and reporting infrastructure for the surveillance of CytoSorb use in real-world critical care settings in an unselected, critically ill patient population. The gathered data will serve as a comprehensive resource to assess the effects of such therapy on patients’ management.

METHODS

The international COSMOS registry is collecting prospective data for patients treated with CytoSorb during routine care in various critical care indications, based on the decision of the treating physicians. Data are collected at baseline, during CytoSorb therapy, 24 hours thereafter, at discharge from the intensive care unit and the hospital, and on day 90. Key outcomes assessed include change in inflammatory biomarkers, vasopressor requirements, fluid balance, organ function and organ support, length of intensive care unit and hospital stay, occurrence of adverse events, and mortality.

RESULTS

The COSMOS registry started with the inclusion of the first patient on July 15, 2022, and is now actively enrolling in 4 countries (Germany, Spain, Portugal, and Italy), with plans to expand to other countries outside of Europe. An initial readout is planned for presentation at an international Critical Care conference in 2024.

CONCLUSIONS

The COSMOS registry is intended to provide comprehensive real-world data on patient outcomes with CytoSorb in various critical care indications, thereby contributing to optimization of patient selection, timing of initiation, and dosing of hemoadsorption treatment.

CLINICALTRIAL

ClinicalTrials.gov NCT05146336; https://clinicaltrials.gov/study/NCT05146336

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/55880
Making Co-Design More Responsible: Case Study on the Development of an AI-Based Decision Support System in Dementia Care (Preprint)
Authors: Lukkien Dirk R M , Ipakchian Askari Sima , Stolwijk Nathalie E , Hofstede Bob M , Nap Henk Herman , Boon Wouter P C , Peine Alexander , Moors Ellen H M , Minkman Mirella M N
Published: January 2024

BACKGROUND

Emerging technologies such as artificial intelligence (AI) require an early-stage assessment of potential societal and ethical implications to increase their acceptability, desirability, and sustainability. This paper explores and compares 2 of these assessment approaches: the responsible innovation (RI) framework originating from technology studies and the co-design approach originating from design studies. While the RI framework has been introduced to guide early-stage technology assessment through anticipation, inclusion, reflexivity, and responsiveness, co-design is a commonly accepted approach in the development of technologies to support the care for older adults with frailty. However, there is limited understanding about how co-design contributes to the anticipation of implications.

OBJECTIVE

This paper empirically explores how the co-design process of an AI-based decision support system (DSS) for dementia caregivers is complemented by explicit anticipation of implications.

METHODS

This case study investigated an international collaborative project that focused on the co-design, development, testing, and commercialization of a DSS that is intended to provide actionable information to formal caregivers of people with dementia. In parallel to the co-design process, an RI exploration took place, which involved examining project members’ viewpoints on both positive and negative implications of using the DSS, along with strategies to address these implications. Results from the co-design process and RI exploration were analyzed and compared. In addition, retrospective interviews were held with project members to reflect on the co-design process and RI exploration.

RESULTS

Our results indicate that, when involved in exploring requirements for the DSS, co-design participants naturally raised various implications and conditions for responsible design and deployment: protecting privacy, preventing cognitive overload, providing transparency, empowering caregivers to be in control, safeguarding accuracy, and training users. However, when comparing the co-design results with insights from the RI exploration, we found limitations to the co-design results, for instance, regarding the specification, interrelatedness, and context dependency of implications and strategies to address implications.

CONCLUSIONS

This case study shows that a co-design process that focuses on opportunities for innovation rather than balancing attention for both positive and negative implications may result in knowledge gaps related to social and ethical implications and how they can be addressed. In the pursuit of responsible outcomes, co-design facilitators could broaden their scope and reconsider the specific implementation of the process-oriented RI principles of anticipation and inclusion.
Co- and Pre-Seismic Crustal Deformations Related to Large Earthquakes Between Years of 2009 and 2023 Using Continuous CORS-TR GNSS Observations in the Anatolian Diagonal (Turkey)
Authors: Dokukin Petr , Guvenaltin Muhammed , Kaftan Vladimir , Toker Mustafa
Published: January 2024

Synoptic animations of internal displacements and deformations of the earth's crust were obtained based on the results of continuous GNSS observations in Eastern Anatolia from 2009 to 2023. The spatiotemporal patterns of the seismic deformation process in connection with the tectonics of the region have been identified. It is shown that dilatation and total shear strains evolve in concert with the migration of the strongest earthquakes Elazig, Elazig-Malatya and devastate Karamanmaraş series. Two years before the occurrence of the devastating earthquakes of 2023, a deficit of internal displacements of GNSS stations developed in the area of their epicenters. The conducted research suggests that the strongest events of 2009-2023 are connected by a unitary seismic deformation process. The most important action in this case is the SW movement of the Anatolian block as monolithic element. In the development of movements and deformations, a flow of increasing stresses is observed in the direction from Karliova Triple Junction to the SW to the area of the strongest seismic events on 02.2023. It originates east of the Karliova Triple Junction where the Arabian Plate encounters an obstacle. The role of mantle flows in the seismic process is assessed
Slaughterhouse’s Animal Welfare Assessement at Bekasi City, West Java
Authors: Pitaloka Katyusa Nandini Dyah , Sudarnika Etih , Pisestyani Herwin
Published: January 2024

The quality of meat sold in Bekasi City is affected by the implementation of animal welfare during the slaughtering process in Slaughterhouses. The research aimed to analyze the animal welfare implementation during the slaughtering process at Bekasi City slaughterhouses. The data was conducted by observing the five-freedom implementation for five slaughterhouses throughout Bekasi City, from the shelter cages to the slaughter. Herding officers ensured no disturbance in the herding route, hitting only animals' backs when the animals stopped walking, and confirmed that animals did not pile up on the herding lane and that live animals did not see the slaughter process. However, some officers still wear clothing that contrasts with the environment, hit the animals repeatedly, and shout at the animals excessively during the herding process. Animal welfare aspects of the slaughter process, such as officers already in position when the animal enters the restraining box, the sharpness of the knife being checked before slaughtering, having a spare knife, and animals slaughtered less than 30 seconds after stunning, have been implemented by all officers. The butcher animal welfare implementation, such as checking the animals' death after being slaughtered, still needs to be improved. This research concluded that Bekasi City's slaughterhouse officers had implemented aspects of animal welfare. However, some improvements are still required through training to increase the competence of officers.
The Comparisons of Phenotypic and Genotypic Resistance of Staphylococcus aureus Isolates Against β-lactam and Tetracycline Antibiotics
Authors: Aziz Fatkhanuddin , Fitriana Fauziah , Setyorini Dian Ritma , Putri Shafira Amalia , Maulina Tifa Restyka , Dewi Vira Kartika , Prihanani Nur Ika , Andityas Morsid
Published: January 2024

Staphylococcus aureus (S. aureus) is a Gram-positive bacteria that causes various diseases in humans and animals. Treatment of S. aureus infection generally uses antibiotics, but what happens is, S. aureus resistance to antimicrobial agents is an increasing global problem. This study aims to compare the phenotypic and genotypic characters of S. aureus from animals isolates against β-lactam and tetracycline antibiotics class. Determination of resistance characteristics of 8 S. aureus isolates was carried out phenotypically by Kirby Bauer and Minimum Inhibitory Concentration (MIC) methods, while genotypically by detecting the blaZ and tet genes. The results of the study showed a relationship between resistance genes and phenotypic test results using the Kirby Bauer and MIC methods. Isolates C, D, F, and TLK with resistance gene characters blaZ-, tetK-, and tetM- showed a sensitive interpretation of the results of the Kirby Bauer and MIC tests. On the other hand, DMG, J, PGT, and KRG isolates were resistant to one or two antibiotics tested, both phenotypic and genotypic (blaZ+, tetK+/tetM+). It found that the MIC levels of some respective isolates were relatively high, isolates J and KRG had an ampicillin MIC level of 32 μg/ml, while isolates J and PGT had 256 μg/ml for oxytetracycline. Although the identification of resistance genes and Kirby Bauer can determine the character of bacterial resistance, MIC determination is necessary to provide qualitative and quantitative information for the benefit of making therapeutic decisions and infection control strategies.
A REVIEW OF FISH DIVERSITY AND MANAGEMENT OF THE VJOSA BASIN: THE FIRST FREE FLOW RIVER PROTECTED AREA IN THE BALKANS
Authors: SHUMKA SPASE , MUÇOLLARI NERTILA
Published: January 2024

Vjosa River, an ecologically important area and the last Europe free-flowing river, is an essential aquatic ecosystem for the Albanian ecological, social, and cultural aspects. Fish and other aquatic species are notable among livings composition found in this region. The river environment is unfortunately seriously threatened by the excessive use of its resources, and hence, the goal of this study was to examine the status of fish biodiversity and the demands of the ecosystem for management. The Vjosa river is home of at least 34 species of fishes inhabiting the river and delta system, of which 29 are native, including eight species endemic to the Balkans. With 12 species, Cyprinidae is by far the most specious family, followed by Mugilidae (five). Salmonidae and Acipenseridae are represented by 2 species each. The remaining ten families are represented by a single species. At least four species (Pseudorasbora parva, Oncorhynchus mykiss, Carassius spp., Gambusia holbrooki) were introduced into the Vjosa basin. The lower river reach is populated by other species as European eel (Anguilla anguilla), species of Family Mugilidae (Mugil cephalus, Liza ramada, Liza salienes, and Chelon labrosus), Seabream (Sparus aurata), Seabass (Dicentrarchus labrax), Flatfish (Platichthys flesus, common sole (Solea spp.), etc., while the resident species associated with saline water include numerically prevalent with the two species Atherina boyeri and Aphanius fasciatus showing presence and significance.
Cyber Security Challenges and Solutions
Authors: Puri Kunal Pradeep
Published: January 2024

Abstract: This article discusses the challenges and opportunities in the field of Cyber Physical Systems (CPSs). It highlights the integration of the physical and digital realms in CPSs and the increasing importance of security in this context. The article provides an overview of the challenges faced by CPSs and suggests potential solutions to address them. It emphasizes the need for preventive measures, coordination, lightweight solutions, and early-stage verification to enhance the security and effectiveness of CPSs.
FPGA Based Air Quality Monitoring System
Authors: Ahmed Ehtesham
Published: January 2024

Abstract: This paper offers a concise review of Air Quality Monitoring Systems employing Field-Programmable Gate Arrays (FPGA). It outlines FPGA architectures, assesses their performance with diverse sensors, discusses integration challenges, and explores recent advancements. Case studies demonstrate practical implementations, validating FPGA's efficacy in delivering real-time, precise air quality data. The review provides valuable insights for future research, contributing to the development of effective and efficient air quality monitoring systems.
Malware Detection of Portable Executable Using Machine Learning and Neural Networks
Authors: Patil Jeet
Published: January 2024

Abstract: Among the more well-known types of automatic detection technology, malware detection includes detection and protection methods against viruses caused by viruses, worms, Trojan horses, spyware, and various types of malicious code. Failure to find a malware program at its inception leaves a space where it will send a significant threat and value to online security not only for individuals, organizations but also the community and the nation. And it seems that antivirus software may fail to detect viruses if it is not updated on a website with an anti-virus engine. The great struggle is to find a new virus because when it encounters new malware behavior, it takes a series of steps based on established law. If the rule of law determines thatthe new behavior is safe the virus remains undetected
KERAGAMAN PERTUMBUHAN ITIK BAYANG PERIODE PERTUMBUHAN
Authors: Rafian Teguh , Arlina Firda , Zulkarnain Zulkarnain , Yurnalis Adytia
Published: January 2024

Penelitian ini bertujuan untuk mengetahui keragaman pertambahan dan bobot hidup itik Bayang sebagai itik pedaging lokal di Sumatera Barat. Penelitian ini menggunakan 205 ekor Itik Bayang yang terdiri dari 106 jantan dan 99 betina yang dipelihara dari umur 1 hari hingga 10 minggu. Penelitian ini dilaksanakan menggunakan metode observasi dengan hasil pengamatan berupa pertumbuhan dan bobot hidup setiap minggunya. Analisis data yang digunakan adalah analisis statistik deskriptif. Hasil penelitian menunjukkan keragaman pertambahan dan bobot hidup itik Bayang sangat tinggi (koefisien keragaman di atas15%). Sehingga dapat disimpulkan perlunya dilakukan seleksi untuk meningkatkan potensi itik lokal unggul di Sumatera Barat.
Fatores explicativos ao recall do patrocínio esportivo entre torcedores sócios e não sócios de um clube de futebol
Authors: Silva Thiago Bruno de Jesus , Sousa Allison Manoel de , Haskel Ana Paula , Lopes Antonio Carlos Vaz
Published: January 2024

O presente trabalho teve como objetivo analisar o efeito do nível de exposição, envolvimento, domínio e similaridade no recall do patrocínio máster de um clube de futebol entre torcedores sócios e não sócios. Foi aplicada uma survey em 1.037 torcedores de um clube de futebol situado no nordeste brasileiro, cujo dados obtidos foram analisados por meio da análise fatorial exploratória e regressão logística. Os resultados confirmaram, de forma parcial, o efeito do nível de impacto da exposição, similaridade e do domínio no recall do patrocínio máster. Observaram-se que não ocorre alteração da chance de consumir produtos e/ou serviços do patrocinador máster quando se é sócio torcedor ou não. Os achados indicam que para a exposição, tem ações diferentes conforme o desempenho do clube na temporada. Na similaridade, os sócios torcedores apresentam maior chance de consumir os produtos e/ou serviços do patrocinador máster. Como contribuição, o estudo avança na discussão ao constatar que há fatores dos torcedores que estão ligados ao futebol que levam ao recall do patrocinador máster. Além disso, os resultados mostram que alguns fatores ligados ao futebol que afetam ou estão presentes na vida dos torcedores do clube implicam no consumo de produtos e serviços do principal patrocinador do clube de futebol.
The Impact of Severe Covid-19 in Iraqi Patients on Serum Angiotensin-Converting Enzyme-2 Level and other Various Diagnosis Biomarkers
Authors: Haleem Kamel Suzan , Jawad Al-Tu'ma Fadhil , Mohi Al-Saegh Riyadh
Published: January 2024

Background: The coronavirus disease 2019 (Covid-19) outbreak is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 (ACE-2) was rapidly identified as the critical functional receptor for SARS-CoV-2. ACE2 is well-known as a counter-regulator of the renin-angiotensin system (RAS) and plays a key role in the cardiovascular system. Given that ACE-2 functions as both a SARS-CoV-2 receptor and a RAS modulator, the treatment for Covid-19 presents a dilemma of how to limit virus entry but protect ACE-2 physiological functions. These will contribute to a deeper understanding of the complex mechanisms of underlying the relationship between the virus, ACE-2, and severity of disease provide guidance for virus intervention strategies.

Aim:  To study the effect of Covid-19 on the levels of some biomarker such as liver enzyme, ferritin, LDH, CRP and ACE-2 activity levels, and their relations with the severity of Covid-19 and the activity levels of angiotensin converting enzyme-2.

Materials and Methods: This case-control study was conducted on 176 male subjects who diagnosed by physician and were divided into three groups: 59 of them were infected with severe covid-19, 54 of them were infected with moderate covid-19 and 63 of them were checked and obtained as apparently healthy control. Severe and moderate patients were collected from Al-Hayat tertiary center at Al-Hussein Medical City, Kerbala Health Directorates, Kerbala – Iraq during April, 2020- June, 2021 with matched age ranged between (23-88) years. In this study, the levels of  ACE-2 was measured through enzyme-linked immunosorbent assays (ELISA) in sera from healthy volunteers as a control group, and patients with moderate Covid-19, patients with severe Covid-19. Anthropometric, biochemical data were analyzed and then measuring the levels of some biomarker such as liver enzyme, ferritin, LDH, and CRP activity levels.

Results: The levels of ACE-2 were differing significantly among groups. However, the level of CRP, Ferritin and LDH were significantly higher in moderate Covid-19 and severe cases of Covid-19 groups compared to control indicating it to be an dependent predictor in the coronavirus disease and prognosis of disease. In contrast the severe infection was correlated with the age and chronic diseases such as pretention and T2DM.