bluuebunny/crossref_metadata_2025 huggingface dataset:
Cardiovascular Effects of Snake Toxins: Cardiotoxicity and Cardioprotection
Authors: Averin Alexey S. , Utkin Yuri N.
Published: November 2021

Snake venoms, as complex mixtures of peptides and proteins, affect various vital systems of the organism. One of the main targets of the toxic components from snake venoms is the cardiovascular system. Venom proteins and peptides can act in different ways, exhibiting either cardiotoxic or cardioprotective effects. The principal classes of these compounds are cobra cardiotoxins, phospholipases A2, and natriuretic, as well as bradykinin-potentiating peptides. There is another group of proteins capable of enhancing angiogenesis, which include, e.g., vascular endothelial growth factors possessing hypotensive and cardioprotective activities. Venom proteins and peptides exhibiting cardiotropic and vasoactive effects are promising candidates for the design of new drugs capable of preventing or constricting the development of pathological processes in cardiovascular diseases, which are currently the leading cause of death worldwide. For example, a bradykinin-potentiating peptide from Bothrops jararaca snake venom was the first snake venom compound used to create the widely used antihypertensive drugs captopril and enalapril. In this paper, we review the current state of research on snake venom components affecting the cardiovascular system and analyse the mechanisms of physiological action of these toxins and the prospects for their medical application.
Avenires Immigrants 2020 Présentation des Diapositives
Authors: Integration Canada Excellence Research Chair in Migration &
Published: November 2021

La présentation d'aujourd'hui:

Notre défi démographique

Comment les immigrants peuvent stimuler l'économie

À propos du projet Avenirs Immigrants at son Cadre

Amorcer une approche pancommunautaire de la planification

Comprendre la communauté
Assistive Device for Rehabilitation of Acute-Stroke Upper Extremity
Authors: Shahzad Naveed
Published: November 2021

Stroke is a medical condition that is the fifth cause of death and a leading cause of disability. The different reasons for stroke are high B.P, obesity, smoking, etc. recovery can only be sped up by regular physiotherapy and willpower of the patient. Regular physiotherapy can be interrupted by other commitments of the patient or by the doctor's unavailability. This may lead to a delay in the recovery process. Therefore, the efforts are needed to tackle the problem. The proposed device can be used to monitor and carry out selected exercises advised by the doctor. Here the upper right limb is our focus because it is the most common area to be affected. Furthermore, android application is also designed which have different consoles for doctor and patient. The patient’s app shows the history and progress of the patient while the doctor sets the time and can also see the progress. Firstly, the unit tracks finger and wrist movements and the signal strength of the muscles being exercised, and then performs assisted flexion / extension manipulation of the limb. The results are shown in the app using the graphs so that the patient and the doctor can both monitor the progress. Thus, this design gives ease to the patient as well as the doctor. With the world shifting towards smart devices and remote monitoring and control, there is a need to apply modern technology in the health dept. using the platform of IOT, certain medical treatments can be made easier for the doctors and effective for the patients. By using different sensors, a microcontroller, Arduino software, mobile application, the patient’s physiotherapy exercises can be monitored, recorded and assisted.
Vatandaşlığın Kazanılması, Küreselleşme ve Uluslararası Göç Üzerinden Bir Değerlendirme
Authors: AKYOL Ender
Published: November 2021

Vatandaşlık kavramının kökeni, antik Yunan ve Roma’ya kadar geriye gitse de asıl olarak modern vatandaşlığın temelleri Westfalya Antlaşması sonrasında ortaya çıkan ulus-devletler düzeninde bulunur. Küreselleşmeyle meydana gelen gezegen ölçeğindeki insan hareketliliği, getirmiş olduğu çeşitli olanak ve eşitsizliklerle milyonlarca insanın doğup büyüdükleri, vatandaşı olarak yaşadıkları ülkeleri terk etmeleriyle birlikte ilerlemeye devam etmektedir. Uluslararası göçle birlikte vatandaşlık statüsüyle göçmenlik arasındaki doğrudan ilişki, devletleri vatandaşlık politikalarında değişiklik yapmaya zorladı. Bu araştırmada tarihsel süreçte antik Yunan’dan başlayarak günümüze kadar vatandaşlık kavramının farklı yönleri ve vatandaşlığa erişim sürecinin belirleyicileri değerlendirilmiştir. Ayrıca araştırmada küreselleşme ve uluslararası göçle birlikte vatandaşlığın kazanılması konusundaki değişen eğilimler, yatırımcı vatandaşlık, küresel hareketlilikteki eşitsizlikler gibi konular ulus-devletler ve bireyler yönünden irdelenmiştir.
Soluções nutritivas salinizadas com cloreto de sódio no cultivo da alface crespa em sistema hidropônico
Authors: Xavier Josilda de França , Azevedo Carlos Alberto Vieira de , Azevedo Márcia Rejane de Q. Almeida , Sales Julio Cesar Rodrigues de , Oliveira Nattan Cardoso de , Fernandes Josely Dantas
Published: November 2021

A pesquisa teve como objetivo a avaliar a produção das três cultivares da alface crespa (Elba, Cristina e Veneranda) cultivadas em sistema hidropônico-NFT utilizando soluções nutritivas salinizadas com cloreto de sódio. O experimento foi conduzido em ambiente protegido, no Centro de Ciências Agrárias e Ambientais-CCAA da Universidade Estadual da Paraíba-UEPB Campus-II, localizado na zona rural do município de Lagoa Seca-PB, com coordenadas geográficas: (7 ° 10 ′ 15 ″ S, 35 ° 51 ′ 14 ″ W). O delineamento foi em blocos casualizados, em esquema de parcelas subdivididas, sendo as parcelas constituídas por soluções nutritivas com diferentes valores de condutividade elétrica (S2-2,4; S3-2,9; S4-3,4; S5-3,9; S6-4,4 e S7-4,9 dS m-1) e as subparcelas por diferentes cultivares de alface crespa (Elba, Cristina e Veneranda), com três repetições. As variáveis analisadas foram: Número de folhas por planta-NFP; Produção Total-PT; Produção Comercial-PC; Diâmetro do Caule-DC; Massa Fresca da Folha-MFF, Massa Seca da Folha-MSF e Massa Seca do Caule-MSC. Independentemente da variável analisada, não houve interação significativa entre as soluções nutritivas e as cultivares. Em relação ao efeito isolado da solução, o maior número de folhas por planta, produção total e comercial e massa fresca de folhas foi obtido com o uso da solução S1. Quanto às cultivares, Veneranda apresentou a maior produção comercial, massa fresca e seca da folha e seca do caule, esta cultivar também apresentou a maior média, mas sem diferir da Elba, quando avaliados o número de folhas e a produção total.
Lessons learned on health information, education and communication for Chikungunya prevention in countries with risk areas: a scoping review
Authors: Oliveira Roberto Carlos de , Tolentino Júnior Dilceu Silveira , Santos Filho Cesar Roberto dos , Martins Yure Rodrigues Araújo , Silva Luciana Setubal Marques , Bacellar Nunes Denise , Albarado Ádria Jane , Sousa Maria Fátima de , Mendonça Ana Valéria Machado
Published: November 2021

With the emergence of Chikungunya arboviruses with its outbreaks and changes in its epidemiology in Brazil, the theoretical-methodological framework of Scoping Review was carried out aimed to prepare a systematic summary of global scientific knowledge and understand the practices and prevention programs of Chikungunya with actions information, education, and communication in health developed in countries with risk areas. References were searched in eight databases until October 2018. Of the 376 articles, 177 were duplicates. Applying the exclusion criteria for reading the title and abstract, 145 were excluded, being considered 19 potentially relevant articles. Health information confers its domain in the literature in entomological and epidemiological surveillance, pointing out challenges for the continuing education of health professionals. Actions for vector control and prevention – especially those related to risk communication – have not influenced behavior, driving only punctual changes, that is, attitudes. However, there is a tendency not to consider community and popular knowledge and practices, as well as the active participation and protagonist of the population.
Effects of bisphosphonates on different zones of the epiphyseal growth plate of rats
Authors: Ponzoni Deise , Fernandes Elissa Kerli , Silva Mateus Muller da , Souza Izabel Cristina Custódio de , Neubert John Kim , Quevedo Alexandre Silva
Published: November 2021

Bisphosphonates (BIS) are indicated for several clinical disorders (e.g., osteoporosis). However, BIS has been associated with osteonecrosis and alterations in osteoclastogenesis and skeletal development. This study aimed to evaluate the effects of BIS (zoledronic acid - ZA and alendronate sodium - AS) on zones of the growth plate of rat femur. Animals (Wistar rats, n = 19) were divided into groups: 1) AS Group: animals received alendronate sodium orally (3 mg/kg per day); 2) ZA Group: ZA was administered intraperitoneally (0.2 mg/kg per week); and 3) Control Group (CG): a vehicle was administered. Animals were euthanized 21 days after the treatment, and femurs were collected for histological analysis. The images of all zones (resting, proliferative, hypertrophic, and calcified) were processed by the Qcapture® software providing a 40 and 400-fold increase.  ZA decreased epiphyseal growth plate cell zones (ZA Group vs. CG) in most cases. Likewise, AS diminished the proliferative zone (AS Group vs. CG). Furthermore, ZA increased the calcified zone (ZA Group vs. CG). Previous works demonstrated that BIS decrease the epiphyseal disc. This reduction is probably due to the shortening of the cellular zones that undergoes calcification/ossification. The present results suggest that BIS should be carefully indicated because these drugs might accelerate epiphyseal closure.
Tobacco stalk lignocellulosic nanofibers characterization for pharmaceutical applications
Authors: Garcia Keth Ribeiro , Weiss-Angeli Valeria , Koester Letícia Scherer , Santos Venina dos , Brandalise Rosmary Nichele
Published: November 2021

Lignocellulosic nanofibers derived from tobacco stalk can have countless applications in polymers composites, textile, cosmetics, and pharmaceuticals. Thus, it is important to evaluate biomass characteristics such as the presence of nicotine. In this study, nanofibers were obtained by mechanical fibrillation while cellulose content (0.5 and 2.0%) and drying methods were varied. Nanofibers were characterized by thin layer chromatography, 1H NMR, morphological analysis, α-cellulose content, Fourier transform infrared spectroscopy, X-ray diffraction and thermal analysis. Results demonstrate the absence of nicotine in tobacco stalk. The grinding mill process was efficient to produce by freeze-drying, nanofibers with fiber’s mean diameter of ~30 nm. Solid concentrations can influence the diameter of obtained fibers. Thermal stability increased and crystallinity decreased when alkali treatment was applied. The characterization techniques applied enable the evaluation of tobacco stalk and expanded its application to pharmaceutics.
Exercício de fortalecimento para o manejo de tendinopatia do manguito rotador
Authors: Henrique Kathleen Kátia Banhos , Jesus David Luna de , Bahia Amanda Maria Alvarenga , Silva Wanderson Fernandes
Published: November 2021

O manguito rotador RC é formado pelos tendões supraespinhal, subescapular, infra espinal e redondo menor. Sendo que todos os tendões tem origem na parte anterior e superior e parte posterior da região do ombro. A estrutura do tendão é formada por seis a nove feixes estruturalmente independentes, e por água e colágeno do tipo I. Objetivo: O objetivo do presente estudo foi determinar se o fortalecimento muscular é eficaz em Tendinopatia do manguito rotador. Métodos: A revisão de literatura foi realizada nas bases de dados virtuais Pubmed e PEDro. Os descritores utilizados foram os seguintes: Exercícios de fortalecimento; fisioterapia; tendinopatia do manguito rotador. Os estudos deveriam obedecer aos seguintes critérios de elegibilidade: artigos publicados na língua inglesa, intervalo de publicação de cinco anos, entre 2017 a 2021, ensaios clínicos randomizados, com pontuação superior a 6 na escala de qualidade PEDro. Resultados: Foram achados 96 artigos, sendo que entraram apenas 7 artigos relacionados ao tema. Conclusão: O presente estudo de revisão bibliográfica verificou a eficácia do fortalecimento muscular na Tendinopatia RC, em todos os estudos inclusos, os exercícios de FM excêntricos e alongamentos obtiveram grandes resultados, desde o período do quadro álgico até a funcionalidade e total mobilidade de cada participante, porém é de sumo importância obter novos estudos afim de traçar novos meios de tratamento da tendinopatia no manguito rotador.
Análise do controle da esteatose hepática em pacientes após cirurgia bariátrica
Authors: Cardoso Danielle Simões , Fornari Jennifer Camila de Souza , Menezes Victor Cury , Santos Marcelo Protásio dos
Published: November 2021

Objetivo: Avaliar a associação entre o controle de esteatose hepática (EH) e o pós-operatório de cirurgia bariátrica em uma instituição privada de Sergipe. Metodologia: Estudo retrospectivo observacional, unicêntrico, com dados coletados por meio de formulário online, previamente autorizado, por 57 pacientes sem distinção de sexo, com obesidade grau III ou grau II associada a comorbidades, submetidos à cirurgia bariátrica pelas técnicas de Gastrectomia Vertical (Sleeve Gástrico) ou Gastroplastia Redutora em Y-de-Roux (Bypass Gástrico) por videolaparoscopia, em uma instituição privada de Aracaju/SE, entre 2019 e 2021. Após aplicados os critérios de exclusão, foram analisados 45 pacientes. Dados analisados por meio de frequência percentual, testes de Pearson e de McNemar. Nível de significância adotado de 5%. Resultado: No pré-operatório foi encontrada prevalência de EH em 66,7% desses e no pós-operatório a prevalência encontrada foi de 16,7%, com redução do grau da patologia ao exame ultrassonográfico para EH grau I. A cirurgia bariátrica foi curativa em 83,3% dos pacientes com EH no pré-operatório, possuindo melhora clínica em 23 (67,6%) daqueles submetidos ao Sleeve Gástrico e 7 (63,6%), ao Bypass Gástrico. Conclusão: Percebeu-se associação significativa entre cirurgia bariátrica e a resolução da esteatose hepática, independente da técnica cirúrgica utilizada.
Levantamento georreferenciado de fisioterapeutas no Brasil
Authors: Veloso Aline Helena Nascimento , Veronezi Rafaela Júlia Batista
Published: November 2021

A disponibilidade de profissionais é um fator desafiador para gestão dos recursos em saúde, sobretudo no Brasil, um país com processo de interiorização e urbanização diferenciado entre as regiões. A distribuição de fisioterapeutas brasileiros ainda é pouco estudada. Georreferenciamento é a conversão da descrição de um local em uma posição na superfície da Terra e uma ferramenta útil na localização de recursos humanos em saúde.  Assim, objetivou-se analisar a distribuição de fisioterapeutas no território brasileiro por meio do mapeamento desses profissionais nos Conselhos Regionais de Fisioterapia e Terapia Ocupacional e unidades federativas. Estudo documental descritivo, número de fisioterapeutas por Conselho Regional obtido via consulta aos portais eletrônicos oficiais ou solicitação dos dados via e-mail dos Conselhos. Foi calculado o número de fisioterapeutas por 10 mil habitantes, ou seja, a proporção da distribuição de fisioterapeutas de acordo com os estados e também para cada Conselho Regional. Para a construção do mapa, foi utilizado o programa GeoDa versão 1.18.0. Houve aumento no número de profissionais em relação a estudos anteriores, com predominância de profissionais na região Sudeste, Nordeste e Sul. Essas disparidades podem ser associadas ao nível de urbanização, população total e taxa de envelhecimento regional.
Força muscular e funcionalidade de pacientes hospitalizados admitidos por afecções respiratórias
Authors: Santos Gabriel Cardoso , Santos Ione Carla dos , Santos Grazielle Batista dos , Ferreira Juarez Alexandre Oliveira , Almeida Lucas Aragão da Hora , Matos Carlos José Oliveira de , Silva Érika Ramos
Published: November 2021

Objetivo: Analisar a força muscular e a funcionalidade de pacientes hospitalizados admitidos por afecções respiratórias. Metodologia: Estudo transversal, realizado em pacientes diagnosticados e internados com doenças respiratórias. As avaliações foram realizadas por meio da Medical Research Council (MRC), Medida de independência funcional (MIF), World Health Disability Assessment Schedule (WHODAS), manovacuometria e dinamometria em pacientes internados no Hospital Universitário de Lagarto. Resultados: Participaram do respectivo estudo 97 pacientes, onde observou-se redução das forças musculares periféricas e respiratórias. Ao analisar a funcionalidade, notou-se moderada dificuldade funcional, sendo ambos instrumentos correlatos (r= -722; p<0,01). Ao analisar a relação entre média de MRC (MMSS) e FPP D e E, demostrou-se que houve correlação alta e positiva (p<0,01) entre as mesmas. Notou-se uma correlação alta e positiva (p< 0,01) entre MRC e MIF, e alta e negativa com o WHODAS (r= -598; p<0,01). Ao avaliar as médias da FPP e do MRC entre os grupos acima de 60 anos e abaixo de 60 anos, verificou-se que o fator idade contribui para a perda da força muscular e, consequentemente, da funcionalidade (p= 0.000). Conclusão: Os pacientes internados por afecções respiratórias agudas ou crônicas agudizadas apresentaram redução da força muscular periférica e respiratória. Esta realidade ressalta a importância de uma assistência fisioterapêutica precoce, pautada na funcionalidade e no ganho de força muscular desses pacientes.
Corticoterapia na sepse: uma revisão integrativa de literatura
Authors: Sousa Laila Caroline Silva , Figueiredo Bárbara Queiroz de , Dutra Dalbert Samuel , Damiani Elizabethe , Ferreira Neto Luis , Sousa Lunalva Gabrielli Veras , Oliveira Rúbia Carla
Published: November 2021

Introdução: a sepse consiste em uma doença inflamatória sistêmica associada a uma infecção com manifestações graves que ocorre por todo o organismo. No entanto, essa infecção não precisa estar necessariamente em todos os locais do organismo, pode estar restrita em apenas um local, mas causar uma resposta inflamatória por todo o corpo para tentar controlar a causa da infecção Objetivo: demonstrar as atuais evidências sobre o uso de corticosteroides no tratamento da sepse em paciente hospitalizados nas unidades de terapia intensiva (UTI’s). Metodologia: trata-se de uma pesquisa descritiva do tipo revisão integrativa da literatura. Foi realizado o cruzamento dos descritores, em inglês: "sepsis", "hemodynamic", "corticosteroids" em português: "sepse", "hemodinâmica", "corticosteroides" e em espanhol: "sepsis", "hemodinámico", "corticosteroides", nas seguintes bases de dados: National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (Scielo), Cochrane Database of Systematic Reviews (CDSR), Google Scholar, Biblioteca Virtual em Saúde (BVS) e EBSCO Information Services. Totalizaram-se 24 artigos científicos para a revisão integrativa da literatura, publicados entre 2011 e 2021. Resultados a melhora na sobrevida com corticosteroides pode resultar da redução da duração do choque, gravidade da inflamação e número de disfunções orgânicas.  Os benefícios demonstrados estão de acordo com os achados de estudos em animais, músculos lisos vasculares isolados e células inflamatórias e em voluntários saudáveis ​​desafiados com endotoxina. A hidrocortisona possui vários benefícios em relação aos recursos de saúde, tais como: é uma droga barata e segura, possibilita menor permanência na UTI, menor tempo de ventilação mecânica e resolução mais rápida da sepse. Conclusão: os glicocorticoides, em especial a hidrocortisona, podem ser utilizados para o tratamento dos pacientes com sepse. Conforme as literaturas utilizadas, os resultados são satisfatórios e possuem um custeio de fácil adesão.
Análise dos efeitos de comportamentos altruístas e egoístas em redes de transporte
Authors: Perez Yuri , Pereira Fabio Henrique
Published: November 2021

Redes de transporte são infraestruturas fundamentais para a dinâmica de grandes centros urbanos. Essas estruturas estão sujeitas a congestionamentos, que trazem um forte impacto social, econômico e ambiental. Neste trabalho, foi construído um modelo de simulação baseado em agentes, a fim de investigar como comportamentos altruístas na seleção de rotas pode afetar os tempos de viagem e a distribuição de fluxo em uma rede de transporte. Métodos: A base de dados aberta OpenStreetMap foi utilizada para obter a estrutura da rede de transporte. A teoria de redes complexas foi usada para realizar a simulação e estimar os impactos do congestionamento. Simulando fluxos de mobilidade, foram analisados como os critérios de seleção de trajeto dos agentes influenciam nos níveis de congestionamento, nos comprimentos de trajeto e nos tempos de viagem. Resultados: altruísta reduz significativamente a propagação de congestionamentos e a formação de agrupamentos de vias congestionadas na rede de transporte, assim como reduz o tempo médio de viagem entre dois pontos, mas aumenta a distância média percorrida numa proporção menor.
Atuação do farmacêutico hospitalar na Unidade de Terapia Intensiva (UTI)
Authors: Oliveira Wellyson Leoncio de , Carvalho Adryanna Rafaelly Araújo de , Siqueira Lidiany Paixão
Published: November 2021

Conhecida como uma das profissões mais antigas, a farmácia tem como principal objetivo a qualidade de vida do paciente. O farmacêutico é o profissional preparado para orientar no uso correto dos medicamentos e pode atuar em diversas áreas, tais como: a farmácia hospitalar que presta um serviço de atividade fundamental no que diz respeito ao uso correto e racional dos medicamentos. O objetivo desta pesquisa é expor a importância do farmacêutico hospitalar junto com a equipe multidisciplinar da Unidade de Terapia Intensiva (UTI). A metodologia utilizada foi o levantamento bibliográfico de artigos em plataformas on-line "Scielo, google academic e Lilacs" e sites oficiais como SBRAFH, AMIB e CFF.  A pesquisa mostra a vantagem deste profissional na equipe multidisciplinar, resolvendo ou prevenindo resultados clínicos negativos causados pelo uso de medicamentos. Portanto, a atuação do farmacêutico hospitalar é vantajosa tanto para a equipe quanto para o paciente, reduzindo erros de prescrição, falhas na administração de medicamentos, que podem trazer danos à saúde, tem uma boa interação com os demais profissionais que prestam serviço, melhorando assim as chances de sobrevivência do paciente criticamente doente, um tratamento mais eficaz e menos duradouro.
Qualidade de vida de indivíduos pós acidente vascular cerebral: uma revisão integrativa
Authors: Conceição Marcos Linco , Conceição Marcelo Linco , Pimentel Paulo Henrique Ramos
Published: November 2021

Introdução: O AVC é considerado uma das questões de saúde pública no mundo inteiro, se tornando a segunda causa no ranking de mortalidade mais comuns nos países, sendo uma das principais causas de incapacidade física temporária ou definitiva. Objetivo: Investigar na literatura existente as repercussões do Acidente Vascular Cerebral (AVC) na qualidade de vida dos indivíduos. Metodologia: Trata-se de uma revisão integrativa da literatura, incluindo as bases de dados da LILACS e MEDLINE, PUBMED e PeDro, Acervo+ Index Base e SciELO, na qual a amostra final para compor está revisão integrativa, foram selecionados onze artigos a partir dos critérios de inclusão e exclusão. Resultados: Identificou-se que a qualidade de vida é o principal elemento afetado em decorrência do AVC, segundo o SF-36, destacando-se os aspectos físicos e emocionais, como sendo os mais afetados e os que mais geram complicações na QV de pacientes diagnosticados com AVC. Considerações finais: O presente estudo possibilitou analisar a QV dos indivíduos e os principais elementos afetados devido aos diversos problemas obtidos em decorrência do AVC, foi possível observar os impactos causados pelo AVC na QV dos indivíduos acometidos, acarretando complicações nos aspectos relacionados a saúde física e emocional principalmente.
A importância da avaliação dos serviços de farmácia no âmbito hospitalar
Authors: Zampronio Nathalia , Piva Leticia
Published: November 2021

Os estudos voltados à área de Farmácia Hospitalar, principalmente os direcionados à avaliação de seus serviços, são tidos como temas pouco explorados no meio científico. O objetivo do presente estudo foi analisar a importância da avaliação da qualidade dos serviços de Farmácia Hospitalar por meio de uma pesquisa de finalidade básica estratégica, com objetivo descritivo e exploratório, de abordagem qualitativa, tendo como instrumento de pesquisa a revisão narrativa de literatura, delimitada por pesquisas científicas de autores na área de farmácia hospitalar. Foram analisados trabalhos em um recorte temporal entre 2007 a 2020, em que foi possível identificar nestes estudos bibliográficos, as avaliações de como este processo permite a identificação de erros, o apontamento de indicadores, e consequentemente como permite a melhoria dos mesmos e seu aperfeiçoamento para os padrões mínimos indicados, demonstrando a importância da constante avaliação da prestação destes serviços. Essa análise bibliográfica permitiu estabelecer a eficácia da avaliação das atividades prestadas para a modificação da prestação dos serviços farmacêuticos hospitalares e consequente o aumento da qualidade dos serviços de saúde, ampliando a produção científica deste tema na área temática da farmácia hospitalar.
MOTION BASED AUTOMATIC STREETLIGHT SYSTEM WITH VEHICLE SPEED SURVEILLANCE
Authors: us Saleheen Rezwan , Salman Shaikat Abu , Islam Saiful , Rahman Md. Rezwanur
Published: November 2021

Extravagance of electrical energy and human
efforts is a common context while using manual switching
of streetlights. In most of the cases, the streetlights remain
ON during evening, night, even daylight the lights
manually are switched OFF. This leads to a lot of energy
wastage because lights keep glowing even when there is
absolutely no necessity of it. This study aims to develop a
smart street light system which glows when the vehicle or
pedestrian enters the certain point of the road and make
the light be in OFF/Dim position when it is not required.
An illustration consisting of a transmitter and a receiver
are made to accomplish the goal. The proposed system can
turn ON the lights while nightfall and OFF the lights
detecting the appearance of daylights. Meanwhile,
presence as per the requirement. Hence, the street light
will ON only when there are road users are present over
there. The system is incorporated with a speed measuring
section to reduce rash driving while the road has relatively
low traffic density. Compared to the conventional street
light system, this streetlight can reduce redundant energy
consumption as well as reckless driving tendency.
A BRIEF REVIEW ON VARIOUS NOISE REDUCTION TECHNIQUES EMANATING FROM WINGS OF AN AIRCRAFT
Authors: Noah D Oyeniran
Published: November 2021

— One of the challenges and a point of need in the
aviation industry is the problem of high level of noise
emanation. There are various sources of noise emanating
from aircraft which are the noises from engine and
airframe including the wings. Noise from the wing is an
important phenomenon to be put into consideration as it
contributes significantly to the noise emanating from
aircraft especially during take-off and landing. Airfoil
noise emission emanate on the wing section of an aircraft
due to the interaction of the airfoil turbulent boundary
layer with the sharp leading edge. Noise reduction then
becomes a thing of concern for many engineers and
researchers who took it upon their shoulder the
responsibility of coming up with design that can help
reduce noise emanating from aircrafts to mitigate the
noise. Due to this, many researchers have focused on
reducing the noise emanating from the aircraft through
various means and approaches which include theoretical,
computational, and experimental analysis. In a means of
compiling and making available a brief review of such
work, for easy and quick access necessitate the need of this
work. This paper focused on giving a summary and review
of different work done by past and current researchers in
the field. The review was based on selected current papers
on the cutting-edge technology towards enhancing
aerodynamic performance of the wing of aircraft and
reduction of noise emanating from it. Although fruitful
results have been achieved in the aerodynamic noise
control, but only little work has been done to summarize
the main findings and progresses in this area. This work
focused on review of work carried out by many
researchers in this area which involves various techniques
and attempts ranging from leading edge serration, trailing
edge serration, active flow actuation, flexible wing using
theoretical, computational, and experimental approach
etc. Additionally, some suggestions were made towards
further study and improv
PATCH AND GROUND PLANE SLOTS EFFECT ON THE RECTANGULAR PATCH MICROSTRIP UWB ANTENNA BANDWIDTH PERFORMANCE
Authors: Ahmed M. Firoz , Kabir M. Hasnat , Touhidul Islam Abu Zafor Md.
Published: November 2021

In this paper, the impact of patch and ground
plane slots on the bandwidth performance of a microstrip
UWB antenna is presented. Our reference antenna is a
microstrip feeding type monopole feature with a
rectangular patch and a partial ground plane. In order to
evaluate the characteristics of the reference antenna
bandwidth, two separate slot types (right-angle triangular
and rectangular) have been inserted into the patch and a
single slot configuration like a rectangular is also inserted
into the partial ground plane on the backside of the feed
line to the appropriate. The influence on the bandwidth
characteristics of single and multiple slot cases is analyzed
using the HFSS simulator. Based on the slot
configurations, the simulation results verify that the
antenna bandwidth can be improved.
CURRENT SITUATION OF COVID-19 AND VACCINATION IN PAKISTAN: JULY 2021
Authors: Naureen Irum , Saleem Ayesha , Nawaz Attique
Published: November 2021

COVID-19is thought to be expended in
Pakistan. On February 26, 2020 first case was
reported in Karachi. On January 30 world health
organization (WHO) coronavirus outbreak on the
sixth public health emergency of international
concern (PHEIC)announced that coronavirus is
epidemic. WHO set up an instructive program
planned to control the increase rate of COVID-19
cases. COVID-19 spread very fastly from person
to person within few days and months leads to
increase rate of Patients. According to latest
updated report 2,452 confirmed coronavirus cases
were reported in Pakistan. According to the
report: 49,503 test were positive: 4.95% deaths (30
persons died) and 903 recoveries were recorded.
Overall the Active Cases 48,850 and critical cases
24 in last 24 hours reported. Coronavirus cases
were reported in Punjab 350,618 deaths 10,881
and recoveries 329,756. In Sindh confirmed cases
were 356,929 deaths 5,720 and recoveries 320,600.
In KPK confirmed cases reported 140,818 deaths
4,386 recoveries 134,144. Balochistan recorded
report of confirmed cases 29,110 deaths 319 and
recoveries 27,261. AJK reported confirmed cases
22,116 deaths 601 and recoveries 19,995 while in
GB confirmed cases recorded 7,414 deaths 117
and recoveries 6, 432. Six vaccines approved in
Pakistan Sinopharm, Cansino, Sinovic, sputnik,
AstraZeneca, and Moderna (mRna-1273).
Pakistan total dose administered 22,735,993 fully
vaccinated 4.550,696 and partially vaccinated
18,185,297. Vaccination start on 3 February and
18 above start on June 3. It was observed that
COVID-19 cases increases due to traveling from
one country to another country. In Pakistan
COVID-19 cases is high due to importation and
traveling to meet other peoples that suffer in
diseases. Pakistan need to follow high and good
precautions rules and strict step in order to
decrease the COVID-19 cases.
MACHINE LEARNING APPLICATION: IMAGE PROCESSING
Authors: Gupta Ayush
Published: November 2021

-In the current scenario of the data world,
the data holds significant information if processed
correctly. The data can be in the form of images which
can prove to be a boon in deriving the useful insights
from it in order to get the knowledge of things at an
early stage itself. But the matter of concern is deriving
the information from the images will be a tedious task
for human beings and would incur a heavy cost and
time. So, an easy and cheaper technique is to teach a
machine efficiently to do the task for us. The concept
of using Machines to do human tasks is known as
Machine Learning. In this paper, I present various
literature reviews regarding image processing in
Machine learning and how image processing has
helped in identifying the issues at early stages so that
they can be resolved easily without causing much
harm. Also, image processing has been a helpful tool
in computer vision.
OVERVIEW OF UNDERGROUND COAL GASIFICATION (UCG) – FOR A PROMISING FUTURE OF INDIA
Authors: Kumar Abhay
Published: November 2021

Underground coal gasification (UCG)
is a process to use and convert deep and
economically un-mineable coal into syngas for
further use in electric power, liquid fuels and
synthetic natural gas etc. Underground Coal
gasification is a very promising option for the
future use of coal present in INDIA. This paper
provides a summary of the UCG description and
its selection criteria. The current status of this
technology in various countries are also been
discussed. Finally, the potential of UCG as a
means for producing syngas from un-mineable
deep sited coal has been discussed and its
challenges as well as opportunities involved.
FIRE HAZARDS IN LITHIUM-ION BATTERIES UNDER OVERCHARGING AND SAFETY STRATEGIES
Authors: Prithviraj M
Published: November 2021

Various Li-ion battery (LIB) fire and blasts
have raised real worries about the safety issues connected
with LIBs, some of those occurrences were in the main
brought about by overcharging of LIBs. Thus, to possess a
superior comprehension of the fire dangers brought about
by LIB overcharging, 2 broadly utilised industrial LIBs,
nickel manganese cobalt oxide (NMC) and lithium iron
phosphate (LFP), were tried during this work. a couple of
boundaries together with the surface temperature, the
flame temperature, voltage, and radiative heat flux were
calculable and investigated. The outcomes demonstrate
that the underlying cathartic voltage increments with the
event of charge cut-off voltage. AN overcharged LIB can
undergo a additional vicious burning cycle and has lower
steadiness than a typical one, and therefore the increasing
cut-off voltage bothers the seriousness. Furthermore, this
work examines the thermal runaway mechanism and
presents completely different thermal runaway mitigation
process, together with separators, flame retardants, and
safety vents. The work then outlines measures for stifling
Fires, and lands up with a bunch of suggestions for future
innovative work.
Quercetin, an organic antioxidant, has been utilized as an
additive in Li-ion cells to boost the chemistry performance
to enhance the cycle life and also the overcharging
characteristics. The quercetin -containing lithium battery
showed an improvement in its electrochemical properties
with 92% capacity retention after 350 cycles. the advance
would possibly result from the formation of a passivation
microstructure (from quercetin oxidation) on the
electrode’s surface. The quercetin-containing batteries
provided long term cycling and a high safety performance,
creating them a viable power supply for applications
involving electrical devices with important safety
requirements.
HANDWRITTEN MATHEMATICAL EXPRESSION RECOGNITION AND GRADING SYSTEM
Authors: Patil Pratik U , Z Zaid , Khot Kajol N , N Sikandar , G Seema
Published: November 2021

Handwritten Mathematical Expression
recognition and grading system is a challenging task in the
field of pattern recognition. A lot of researchers have
already worked on Handwritten Mathematical Expression
recognition and have used various classifiers. In past,
Convolutional Neural Network, also called CNN, has been
highly used for recognizing patterns. In this paper, We
propose an idea to recognize HME and evaluate offline
using CNN for classification. The steps included are, first
the worksheet is scanned and is sent to the work-spaces
detection module where it will return all the rectangular
work-spaces from the given worksheet, then the workspaces are sent to the line extraction module to extract all
the lines. The extracted lines are then passed to the
character segmentation module where it will segment the
character and then characters will be classified using deep
learning model DCCNN. Finally, the evaluation module will
assess the line and draw a green/red bounding box
depending on whether the line is correct or not.
DESIGN AND FABRICATION OF 3D PRINTER
Authors: Gupta Ativya , Gupta Garima , Srivastava Harshit , Yadav Er. Sunil Kumar
Published: November 2021

The project entitled Design and Fabrication
of a 3D Printer defines about the different types of D
printer being used in the market and the final analysis
of the various input and output parameters that has
been taken into consideration.
It also describes about the present application and the
future scope of the 3D Printer.
A 2D-sketch of butterfly was been prepared in the
Solidworks software which was further extruded into
its 3D-model. After converting the 2D sketch into 3D
model the file was saved and transferred in the STL
(Standard Tessellation Language) file format for the
final layer by layer manufacturing in the 3D printer.
Fused Deposition Modelling (FDM) type of 3D printer
is been used in the project which does the modelling by
depositing the filament through heated nozzle layer by
layer on the heated plate to form the final object.
Thus taking the input parameter as the Nozzle
diameter, travel speed and layer height we considered
the output parameter as Marching time and did our
analysis using Design OF Experiments (DOE).
The results after the analysis were like the more nozzle
diameter we will use the less machining time will be
required with increased layer height and travel speed
though with more nozzle diameter the quality of the
product would vary a bit but it can be accepted if not
much précised or complex design is required.
Similarly, the less diameter would require more
machining time with less layer height and less travel
speed, though the quality of the product will be
excellent normally also and for more complex and
intricate designs as well.
THE FREEDOM OF TRAVELLING AND THE ALCHEMIST: HAPPINESS IS WITHIN US
Authors: Thapa Prakash
Published: November 2021

The protagonist of The Alchemist
Santiago longs to travel to fulfill his dreams and
likes to be liberated from his status quo of life in
essence. He thinks that one can discover the new
dimension of life by travelling into the faraway
land; this also shows the archetype of nomadic
instinct of human beings, for they have always
travelled from one place to another in search of
prosperity and fulfillment. He desires something
new so that he can come out of the conventional
pattern of life in general. For him travelling to the
unknown brings freedom, wealth and
emancipation in life. So he chooses to travel and
keeps dreaming.
OVERVIEW OF GRINDING SYSTEMS AND MV DRIVE TECHNOLOGIES IN MINES
Authors: Wankhede Ashok K , Sharma Dr Archana , Fernandis Prof B G
Published: November 2021

Mining of ore has become technology driven
operation today. The mined ore needs to be processed at
site so that further operations are convenient and cost
effective and high volumes are processed. Grinding of ore
is one of the most important and power intensive operation
in mining. In order to process the ore at faster rate, sizes of
mills have gone bigger and bigger. While mill diameters
have touched 42 feet, at the same time power required has
gone upto 38 MW per system. Because of huge processing
requirements, mills have migrated from geared to gearless
and accordingly changes in mechanical systems, drive
motors and power converter technologies have thrown a
bigger challenge. Scaling up the equipment also has major
requirement of robust mechanical design to reduce
maintenance and ensure reliable operation.
This paper focuses on overview of various grinding
systems, drive and converter technologies and other aspects
like design, operation and maintenance. Comprehensive
literature survey conducted and systems which are being
used today are compared with respect to cost, efficiency
and drawbacks. Also possible advanced technologies with
respect to improvement in Drive is also suggested.
Strengthening the protection of critical infrastructure: domestic realities and international cooperation
Authors:   SESE “The Academy of Financial Management”, KLYMENKO Kateryna , SAVOSTIANENKO Maksym ,   SESE “The Academy of Financial Management”
Published: November 2021

The article emphasizes that the creation of a state system of critical infrastructure protection requires legal regulation of the basic principles of its operation, the introduction of common approaches to the management of system facilities at the state and local levels, defining the principles of interaction between state bodies and society. and citizens. Specific problematic aspects of the sphere of critical infrastructure protection in the process of reform are considered, among which: lack of a unified national system of critical infrastructure protection; insufficiency and inconsistency of normative-legal regulation on protection of systems and objects of critical infrastructure; lack of a state body responsible for coordinating actions in the field of critical infrastructure protection, uncertainty of powers, tasks and responsibilities of central executive bodies and other state bodies in the field of critical infrastructure protection, as well as rights, duties and responsibilities of owners (managers) critical infrastructure; underdeveloped public-private partnership in the field of critical infrastructure protection and uncertainty of sources of funding for critical infrastructure protection measures, insufficient level of international cooperation in the field of critical infrastructure protection. Some issues of strengthening the protection of critical infrastructure in the context of cooperation with IFI`s have been studied. The authors consider the financing of infrastructure development projects implemented in Ukraine through borrowings raised by Ukraine from international partners, including the EBRD, the World Bank, KfW and others. The need to adopt the draft Law of Ukraine “On Critical Infrastructure” № 5219 was emphasized. To support the critical infrastructure protection management system, it is proposed to adopt a Critical Infrastructure Protection Management Strategy for the medium term until 2025, which will form the basis for sustainable and inclusive development of the critical infrastructure protection system and the national economy in general.
Features of operation regulation with virtual assets for mining activities
Authors:   SESE “The Academy of Financial Management”, DMYTRENKO Tetiana , VOLKOVA Valeriya
Published: November 2021

The article deals with the peculiarities of suspicious transactions in financial markets related to the use of cryptocurrencies, it also studies current issues regarding the classification of virtual assets. The features of countering suspicious transactions in financial markets associated with the use of cryptocurrency are highlighted. Topical issues of taxonomy of virtual assets and risk assessment of service providers' activities in assessing the risk of operations with virtual assets related to their use in legalization operations are investigated. The concepts of regulation of virtual assets are considered. The concept of mining, the problem of the relationship of varieties of mining activity to the classification of certain types of activity, its legalization are defined, and recommendations for the classification of mining activities are given. The relationship between miners, validators and virtual asset providers (VASP) in the event of a cyberattack or in the presence of certain rights to the network has been analyzed, which leads to the classification of this type of activity as risky regarding the use of cryptocurrencies with criminal intent. It is also underlined the need to introduce a risk-based approach to countering money laundering and terrorist financing (AML / CFT) by national state supervisory and law enforcement agencies, enterprises involved in the virtual asset market, preventing threats and developing a legislative framework for regulation the crypto market and interaction on these issues at the international level.
Analysis of Saliva and Gingival Crevicular Fluid Immunoglobulin A in Adults Having Different Caries Status
Authors: GÜL Pınar , ÇELİK Neslihan , HANCİ Hayrunisa , AYDIN Tuğba , AKGUL Nilgun , SEVEN Nilgun
Published: November 2021

Objective: The aim of the study was to compare the salivary IgA and gingival crevicular fluid IgA levels in caries active and caries free subjects.
Methods: The study was carried out on 40 subjects divided into two groups, Group I caries free, (DMFT =0) and Group II caries active, (DMFT >10). Saliva and gingival crevicular fluid samples were obtained and plaque index, gingival index, gingival crevicular fluid volume and salivary flow rate were determined. The levels of S. mutans and lactobacillus were determined by culture. IgA concentrations of saliva and gingival crevicular fluid samples were determined using the ELISA. Data were analyzed using the Mann-Whitney U and χ2 tests (α = 0.05).
Results: Gingival crevicular fluid volume, plaque index and gingival index values of group II were significantly higher than group I (p< 0.05). Although lactobacillus counts of group II were higher than group I, no statistically significant differences were observed for microorganism counts (p>0.05). Salivary flow rate, gingival crevicular fluid-IgA and saliva-IgA levels were no statistically significant between the groups (p>0.05).
Conclusion: The present study showed that microorganism counts in the saliva did not by themselves influence the DMFT index. There is no dependence between secretory immunity and dental caries in subjects.