bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of reinforcement size hybridization on the wear properties of SiCp/Cu Composites
Authors: Zhan Yongzhong , Xie Haofeng , Shi Xiaobo
Published: March 2022

Reinforcement size is an important factor that influences the mechanical and tribological properties of particulate reinforced metal matrix composites (PRMMCs). However, relatively few works have been carried out to investigate this issue. There are still many problems to be solved, on the optimum design of PRMMCs of tribological applications. In this work, copper-matrix composites reinforced with SiC particles of mono-size and hybrid-size are fabricated through a powder-metallurgy plus hot-extrusion method. The main purpose is to investigate the effect of reinforcement size hybridization on the dry sliding wear behavior of PRMMCs. The results indicate that finer particles result in a better reinforcing effect and significantly reduce the plastic flow and adhesive transfer of surface and subsurface material. The deeply embedded coarse particles bear the external applied load and resist the plowing effect of the counterpart. The different roles of the particulate components with various sizes promote the exertion of the other’s strengthening function, therefore resulting in higher wear resistance.
Filtration resistance during pressure filtration tests of liquid aluminium alloys
Authors: Cao Xinjin
Published: March 2022

Prefil Footprinter, a portable pressure filtration instrument, is usually employed to detect liquid metal quality. However, no investigations have ever been done to determine overall filtration resistance and resistance of the “clean” filter media. Based on the identification of flow behaviour using the derivative methods, classic filtration equations have been effectively used to estimate total filtration resistance for the first time. The variations of overall resistance during filtration provide a new approach to understand filtration behaviour. The resistance values of the “clean” filter media have been obtained for the first time. An innovative method has been developed to obtain the resistance of the “clean”' filter media through the backward extrapolation of the overall filtration resistance versus filtrate weight or filtration time curves over the steady stages operating in incompressible cake mode.
Effect of tin added to the zinc bath on the formation and the microstructure of hot-dip galvanized coatings
Authors: Avettand-Fènoël Marie-Noëlle , Reumont Guy , Goodwin Frank , Perrot Pierre , Foct Jacques
Published: March 2022

The present study aims to analyze the effect of tin, added to zinc bath containing aluminium, on the microstructure and on the development of spangles of continuous hot-dip galvanized coatings. Different experimental conditions have been explored and the mechanism of nucleation and growth taking place during the solidification of the coating are discussed with the support of a thermodynamics approach.
Indentation behaviour of (011) thin films of III–V semiconductors: polarity effect differences between GaAs and InP
Authors: Largeau Ludovic , Patriarche Gilles , Le Bourhis Eric , Rivière Jean-Pierre
Published: March 2022

(011) thin films of GaAs and InP (220 and 250 μm thick, respectively) were deformed by a Vickers indenter at elevated temperatures (350 – 400 °C) under loads in the range 0.4 – 2.9 N. For loads higher than 1.9 N, symmetric punching through InP was detected at the opposite face while it was asymmetric through GaAs. In InP, when the punching mechanism took place, pile-up around the indent site progressively disappeared. Moreover, the measured plastic volumes reveal that plastic flow throughout the specimens is volume conservative, implying that pile-up and punching events are related. In GaAs, the anisotropic pile-up plasticity was studied using transmission electron microscopy. Models describing the material flow through the samples and reverse flow of matter are proposed.
Effect of LiYO2 addition on sintering behavior and indentation properties of silicon nitride ceramics
Authors: Matovic B. , Rixecker G. , Boskovic S. , Aldinger F.
Published: March 2022

The influence of the sintering additive LiYO2 (5– 15 wt.%) on sintering behavior, microstructure and mechanical properties of Si3N4 ceramics was investigated. Since LiYO2 enables densification of Si3N4 at extraordinarily low temperatures, sintering was carried out in the range from 1200– 1700 °C. Densification was found to be enhanced with increasing additive content due to an increasing volume fraction of the liquid. The phase transformation and grain growth occurred through a solution-reprecipitation mechanism, where the precipitation took place preferentially on pre-existing β-Si3N4 nuclei (of which the starting powder already contained 20 wt.%). The indentation fracture toughness increased with both sintering time and additive content as a result of the growth of elongated grains.
Thermodynamic assessment of the systems La2O3–Al2O3 and La2O3–Y2O3
Authors: Fabrichnaya O. , Zinkevich M. , Aldinger F.
Published: March 2022

The thermodynamic parameters of the systems La2O3– Al2O3 and La2O3–Y2O3 are assessed using the Calphad technique. The available phase equilibrium data and calorimetric measurements for the LaAlO3, perovskite phase have been used. The calculated phase diagrams are in reasonable agreement with experimental results. However, experimental data for the La2O3–Y2O3 system demonstrated large uncertainty and new experimental study of solid state reactions would be useful to verify the calculated diagram. Experimental investigations of thermodynamic properties are necessary for both systems to verify the calculated phase diagrams and thermodynamic properties.
Plane bending fatigue behavior of interstitial-free steel at room temperature
Authors: Islam Mohammed Aminul , Tomota Yo
Published: March 2022

Interstitial-free steels are widely used as thin sheet for automobile external panels. For this type of application, essential properties of the steel are deep-drawability and stretch-formability. However, low-strength interstitial-free steel is nearly pure iron and work on fatigue fracture behavior of this steel might be adopted as a basic study to understand the behavior of high-strength steels used for structural components. In this study, the fatigue fracture behavior of low-strength interstitial-free steel has been studied at room temperature in air and in an argon atmosphere. Fractographic observations on fatigue fracture surfaces reveal a mixed type of fracture mode (intergranular and transgranular cracking) for all specimens. The major portion of intergranular fracture has been found at the regions of low and medium crack lengths. Further increase in the crack length causes a decrease in the proportion of intergranular cracking and, finally, the fracture mode becomes completely transgranular. At the same test temperature, the proportion of intergranular fracture drastically decreased when the test was carried out in the argon atmosphere.
Processing and mechanical behaviour of a dual scale particle strengthened copper composite
Authors: Tiziani C. , Götting M. , Rösler J.
Published: March 2022

Oxide dispersion strengthened (ODS) and dual scale particle strengthened (DSPS) copper composites were successfully manufactured by a powder metallurgical processing route, containing Al2O3 particles with a mean diameter of 17 nm as dispersoids and, in the case of the DSPS material, 15% tungsten fibres about 3 mm long. Their mechanical behaviour was investigated at ambient and elevated temperatures. The ODS material displayed mechanical properties comparable to those of commercial GlidCop® alloys. Addition of tungsten fibres in case of the DSPS material increased the elevated temperature flow strength relative to the ODS counterpart by about 12 %. This result is rationalised by finite element calculations, taking fibre orientation, plastic deformation of the fibres as well as the role of the fibre coating into account.
Threshold dynamics of an HIV-1 model with both virus-to-cell and cell-to-cell transmissions, immune responses, and three delays
Authors: Miao Hui , Jiao Meiyan
Published: March 2022

In this paper, the dynamical behaviors of a multiple delayed HIV-1 infection model which describes the interactions of humoral, cytotoxic T lymphocyte (CTL) immune responses, and two modes of transmission that are the classical virus-to-cell infection and the direct cell-to-cell transmission are investigated. The model incorporates three delays, including the delays of cell infection, virus production and activation of immune response. We first prove the well-posedness of the model, and calculate the biological existence of equilibria and the reproduction numbers, which contain virus infection, humoral immune response, CTL immune response, CTL immune competition, and humoral immune competition. Further, the threshold conditions for the local and global stability of the equilibria for infection-free, immune-free, antibody response, CTL response, and interior are established by utilizing linearization method and the Lyapunov functionals. The existence of Hopf bifurcation with immune delay as a bifurcation parameter is investigated by using the bifurcation theory. Numerical simulations are carried out to illustrate the theoretical results and reveal the effects of some key parameters on viral dynamics.
Evaluation of endocrinological involvement and metabolic status in patients with Gaucher disease Type 1 and Fabry disease under enzyme replacement therapy
Authors: Ersoy Melike , Pişkinpaşa Hamide
Published: March 2022

Objectives

Gaucher disease type 1 (GD1) and Fabry disease (FD) are the two most common lysosomal storage diseases. For over three decades, effective enzyme replacement therapies (ERTs) have changed the fate of patients and offered a longer chance of survival and improve their quality of life.

Methods

The clinical and molecular findings, endocrinological features and metabolic status of 26 patients (16 with FD, and 10 with GD1) were evaluated. The results were compared to age- and gender-matched healthy individuals.

Results

Patients with GD1 and FD were followed for 7.2 ± 4.7 and 6.4 ± 4.3 years, respectively. Calcium and magnesium levels in patients with GD1 were lower than in controls (p=0.01; p=0.002). Osteoporosis was detected in 20% (n=2) of GD1 patients and 12.5% (n=2) of FD patients. The HbA1c value of GD1 patients was significantly lower than both in control and Fabry patients (p=0.004; and p=0.007, respectively). There was a negative correlation between LysoGb3 and female gender (p=0.04; r=−0.49), but no correlation was found with any other biochemical parameters. There was a negative correlation between the LysoGb1 level and the neutrophil (p=0.03; r=−0.711) and thrombocyte levels (p=0.02; r=−0.767), and a positive correlation with ferritin levels (p<0.001; r=0.867).

Conclusion

Long time effective ERT seems to have beneficial effects on metabolic and hormonal status as well as primary target organs in both FD and GD1 patients.
Framework materials for supercapacitors
Authors: Dai Yunyi , Liu Chunli , Bai Yang , Kong Qingquan , Pang Huan
Published: March 2022

Framework materials, including metal–organic framework materials (MOFs), Prussian blue/Prussian blue analogs (PB/PBAs), and covalent framework materials (COFs), are promising candidates for fabricating electrodes for use in electrochemical devices, especially supercapacitors. Supercapacitors have been widely investigated over the past decade. Active materials as electrode materials are vital to the development of the next generation of supercapacitors. Therefore, designing and fabricating novel electrode materials endowed with superior specific capacitance, perfect cycling stabilities, and distinguished power/energy density are crucial. In this review, we focus on framework materials – MOFs, PB/PBAs, and COFs – and report electrode materials based on their pristine forms, derivatives, and composites for supercapacitors. Recent advances and potential applications of framework materials in supercapacitors are also discussed. Furthermore, we discuss the opportunities and challenges for the future direction of supercapacitors based on framework materials.
An overview on the reproductive toxicity of graphene derivatives: Highlighting the importance
Authors: Hadizadeh Nastaran , Zeidi Saba , Khodabakhsh Helia , Zeidi Samaneh , Rezaei Aram , Liang Zhuobin , Dashtizad Mojtaba , Hashemi Ehsan
Published: March 2022

With the glorious discovery of graphene back in 2004, the field of nanotechnology was faced with a breakthrough that soon attracted the attention of many scientists from all over the world. Owing to its unique bidimensional structure and exquisite physicochemical properties, graphene has successfully managed to cave its way up to the list of the most investigated topics, while being extensively used in various fields of science and technology. However, serious concerns have been raised about the safety of graphene, for which numerous studies have been conducted to evaluate the toxicity of graphene derivatives in bothin vitroandin vivoconditions. The reproductive toxicity of graphene is one of the most important aspects of this subject as it not only affects the individual but can also potentially put the health of one’s offsprings at risk and display long-term toxic effects. Given the crucial importance of graphene’s reproductive toxicity, more attention has been recently shifted toward this subject; however, the existing literature remains insufficient. Therefore, we have conducted this review with the aim of providing researchers with assorted information regarding the toxicity of graphene derivatives and their underlying mechanisms, while mentioning some of the major challenges and gaps in the current knowledge to further elucidate the path to exploring graphene’s true nature. We hope that our work will effectively give insight to researchers who are interested in this topic and also aid them in completing the yet unfinished puzzle of graphene toxicity.
After the Theological Turn: Towards a Credible Theological Grammar
Authors: Koci Martin
Published: March 2022

The theological turn provokes much debate on the nature of phenomenology but almost none on the definition of theology. I argue, however, that the theological turn not only enlarges the field of phenomenological exploration but also provides theology with a conceptual apparatus that can contribute to formulating rigorous theological positions. In the first step, I question the debate dominated by philosophers of religion which created a normative – restrictive – category of the theological turn. Instead, I argue that the full potential of the theological turn in phenomenology will only be revealed when we accept it as a descriptive category – a tendency that has always in fact been present in phenomenology. In the second step, I move towards theology to argue that the phenomenological engagements with the original theological thoughts are less de-theologized than they are transformed and in their new version offered back to theology, for which they can have crucial relevance. Hence, what is truly interesting after the theological turn is not so much the boundary between theology and phenomenology but their mutual and undeniable encounters.
MMA-based fast-curing repair materials suitable for low-temperature application
Authors: He Yashu , Wang Zhenyang , Wen Fengyu , Sirotin Igor S. , Mu Jianxin , Kireev Vyacheslav V.
Published: March 2022

In this study, the application of methyl methacrylate (MMA) resin as the binder and standard sand as the aggregate has been employed to prepare the repair materials that can be cured in the sub-zero temperature environment. For this purpose, the redox initiation system of benzoyl peroxide (BPO) and N,N-dimethyl-p-toluidine (DMPT) has been used. Subsequently, the influence of initiator and accelerator content on the compressive strength, flexural strength, curing time and other properties of the materials has been revealed. At an ambient temperature of 0 °C, with BPO = 4.5% and DMPT = 3.5%, the developed repair materials can be cured within 31 min, and the 1 h compressive strength reaches 84.6 MPa. At an ambient temperature of −25 °C, with BPO = 4% and DMPT = 5%, the repair materials can be cured within 43 min, with the 1 h compressive strength reaching 53.4 MPa. The materials can be swiftly cured at low-temperature and exhibit excellent mechanical properties, thus, confirming their suitability for extreme environments. Fourier transform infrared spectrometry (FT-IR), scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and other techniques have been employed to characterize the developed materials.
Molecular dynamics of C–S–H production in graphene oxide environment
Authors: Kai Guo , Miaohong He , Wenhao Pan , Jinguo Wu
Published: March 2022

The process of calcium silicate hydrate (C–S–H) generation in graphene oxide (GO) nanoslits was investigated via molecular dynamics simulations using the structural polymerization reaction of silica chains in the synthesis of silica gels. The structural evolution of C–S–H, radial distribution functions, chemical components, and distribution of Q

n
units in the system were analyzed to investigate the influence of GO on the early growth mechanism of C–S–H and compare the structural differences of C–S–H in the presence and absence of GO. The results showed that the proportion of silicon atoms bonded to bridge-site oxygen atoms in the C–S–H structure increased in the presence of oxygen-containing graphene groups. Ion adsorption in the GO surface layer led to an increase in the degree of polymerization of C–S–H. The nucleation and templating effects of GO were confirmed, revealing the intrinsic mechanism for the formation of GO-modified reinforced cementitious materials.
Response analysis and optimization of the air spring with epistemic uncertainties
Authors: Kong Feng , Bai Yu , Liang Xifeng , Lu Zhaijun , Yin Shengwen
Published: March 2022

Traditional methods for the optimization design of the air spring are based on the deterministic assumption that the parameters are fixed. However, uncertainties widely exist during the manufacturing stage of the air spring. To model the uncertainties in air springs, evidence theory is introduced. For the response analysis of the air spring system under evidence theory, an evidence theory-based polynomial chaos method, called the sparse grid quadrature-based arbitrary orthogonal polynomial (SGQ-AOP) method, is proposed. In the SGQ-AOP method, the response of the air spring is approximated by AOP expansion, and the sparse grid quadrature is introduced to calculate the expansion coefficient. For optimization of the air spring, a reliability-based optimization model is established under evidence theory. To improve the efficiency of optimization, the SGQ-AOP method is used to establish the surrogate model for the response of the air spring. The proposed response analysis and the optimization method were employed to optimize an air spring with epistemic uncertainties, and its effectiveness has been demonstrated by comparing it with the traditional evidence theory-based AOP method.
Residual stress relief mechanisms of 2219 Al–Cu alloy by thermal stress relief method
Authors: Song Hechuan , Gao Hanjun , Wu Qiong , Zhang Yidu
Published: March 2022

Monolithic thin-wall components of 2219 Al–Cu alloy are widely used in aerospace and military fields, and usually treated with solution and quenching to improve their comprehensive performance. However, a high magnitude residual stress is introduced into the components during the quenching process, which is unfavorable to the subsequent manufacturing process and service performance. Therefore, residual stress relief is essential to enhance the performance of the components. A conventional effective method is thermal stress relief (TSR). However, the underlying mechanisms of TSR still remain unclear and lack a quantitative interpretation. In the present work, the evolution and distribution laws of the residual stresses, tensile properties, Vickers hardness, dislocations, precipitated phases, and metallography during TSR were investigated. Based on the experimental results, dislocation theory and strengthening mechanisms were applied to reveal the underlying mechanisms of the residual stress relief by TSR. The results showed that the circumferential and axial residual stress relief rates can reach 86.37 and 85.77% after TSR, respectively. The residual stress relief after TSR is attributed to the dynamic evolution of dislocation configuration and density. The improvement in the mechanical properties mainly depends on the precipitated phases and is also affected by the stress orientation effect caused by the residual stress.
Sparse latent factor regression models for genome-wide and epigenome-wide association studies
Authors: Jumentier Basile , Caye Kevin , Heude Barbara , Lepeule Johanna , François Olivier
Published: March 2022

Association of phenotypes or exposures with genomic and epigenomic data faces important statistical challenges. One of these challenges is to account for variation due to unobserved confounding factors, such as individual ancestry or cell-type composition in tissues. This issue can be addressed with penalized latent factor regression models, where penalties are introduced to cope with high dimension in the data. If a relatively small proportion of genomic or epigenomic markers correlate with the variable of interest, sparsity penalties may help to capture the relevant associations, but the improvement over non-sparse approaches has not been fully evaluated yet. Here, we present least-squares algorithms that jointly estimate effect sizes and confounding factors in sparse latent factor regression models. In simulated data, sparse latent factor regression models generally achieved higher statistical performance than other sparse methods, including the least absolute shrinkage and selection operator and a Bayesian sparse linear mixed model. In generative model simulations, statistical performance was slightly lower (while being comparable) to non-sparse methods, but in simulations based on empirical data, sparse latent factor regression models were more robust to departure from the model than the non-sparse approaches. We applied sparse latent factor regression models to a genome-wide association study of a flowering trait for the plant Arabidopsis thaliana and to an epigenome-wide association study of smoking status in pregnant women. For both applications, sparse latent factor regression models facilitated the estimation of non-null effect sizes while overcoming multiple testing issues. The results were not only consistent with previous discoveries, but they also pinpointed new genes with functional annotations relevant to each application.
Measuring thermal properties of thin layers with rough surfaces by using the bidirectional heat flow approach
Authors: Fladischer Katrin , Leitgeb Verena , Fernbach Simon , Mitterhuber Lisa
Published: March 2022

Thermophysical properties of materials and the optimization of the heat transfer are becoming more and more important for industrial applications of micro- and nanoelectronic devices. Thin layers in the micrometer to nanometer range are used to give specific functions to the devices. Since the thermophysical properties of thin layers differ from bulk material, this data is required for precise predictions of thermal management. One way to obtain the thermal properties of thin layers is the optical-based Time Domain Thermoreflectance (TDTR) method. To carry out TDTR measurements with a low level of uncertainty, the samples under study must meet requirements related to the surface roughness and a low level of optical scattering. The range of samples analysable by TDTR can be extended by applying the so-called bidirectional heat flow approach. This approach opens the possibility to assess thermal properties of materials with rough surfaces as well. The validity of the implemented model was shown by the characterisation of a test sample with well-known thermal properties fabricated for this purpose out of poly(methyl methacrylate) (PMMA) roughened with acetone:ethanol. The results obtained by TDTR measurements were compared to literature values, demonstrating the applicability of the bidirectional heat flow approach for this setup.
No case tampering once transfer domain is formed!
Authors: Jarrah Marwan , Al-Jarrah Rasheed , Al-Shawashreh Ekab
Published: March 2022

This research article offers empirical evidence from Standard Arabic (SA) that an existing structural case assigned on an element by one head can be overridden by a new structural case assigned by a different head as long as the element (or one of its copies) has not become part of any previous transfer domain defined by the Phase Impenetrability Condition (PIC) (see Chomsky, Noam. 2000. Minimalist inquiries: The framework. In Roger Martin, David Michaels & Juan Uriagereka (eds.),Step by step: Essays on minimalist syntax in honor of Howard Lasnik, 89–155. Cambridge, MA: MIT Press). Our main evidence comes from the patterns of case assignment of the overt complementizerʔinnain SA.ʔinnacan only assign case to elements that otherwise bear default case, including a topical object or a topical subject as well as elements that are assigned case by T0such as a contrastively focused subject. On the other hand,ʔinnanever assigns case to a contrastively focused object (that is located in CP) which is argued to be base generated in its thematic position within the transfer domain of v*P. These facts are taken together as evidence that a structural case assigned to elements within a phase is temporary (as it can be overridden) until the transfer takes place. We attribute this to the workings of a transfer principle labelled asThe Case-Chain Uniformity Principle(CCUP) that demands that a non-trivial chain (i.e., a discontinuous entity) be only assigned one case value in the interface.
A comparative analysis on the safety and efficacy of Covaxin versus other vaccines against COVID-19: a review
Authors: Talukder Abhijita , Kalita Chayanika , Neog Nayanika , Goswami Chayanika , Sarma Mrinal Kashyap , Hazarika Iswar
Published: March 2022

Since the identification of the genomic sequence of SARS-CoV-2, an unprecedented effort is being made until this date for the development of a safe and effective vaccine by pharma companies and laboratories worldwide. To attain herd immunity and quite possibly recover from this pandemic, which has claimed the life of about 4.23 million people, an exceptional effort has been made by the scientific community for the development of a vaccine. Various vaccines have been developed based on different platforms and each of them seems to possess its own merits and demerits based on its safety, immunogenicity, the durability of immunity, dosing schedule, technological platform, and ease of manufacture and transport. Based on these parameters this review aims to critically assess the efficacy of Covaxin and compare it with other vaccines in the WHO EUL list and perform a comparative analysis of COVID-19 vaccines which are in phase 3 and phase 4 of clinical trials. This will help us determine where COVAXIN stands against other vaccines and vaccine candidates based on these parameters which will ultimately help us determine the best vaccine that could potentially eradicate the COVID-19 pandemic.
The prospects of Wattpad: Virtual library of the future or a publisher’s submission site?
Authors: Poliakova Elizaveta
Published: March 2022

The popularization of the internet has enabled the creation of a number of online publishing outlets. Peer-to-peer platforms allow readers and writers to interact with each other, seemingly eliminating the need for traditional gatekeepers in the form of the editor and publisher. These platforms, however, have been credited with the disturbance of the publishing ecosystem. One popular peer-to-peer site is Wattpad. Conversely, as discussed in this paper, the creators of Wattpad do not want to disrupt the traditional publishing infrastructure but become a part of it. The study analyzes the values incorporated in the design of Wattpad’s website and the mobile app through utilizing the walk-through method of data collection. The researcher outlines how a writer-user and reader-user could potentially be prompted to utilize the platform by analyzing the vision, operating model, and governance of the platform. The study discusses that there are hierarchies at play with the writer-user valued to a greater extent as an individual than the reader-user who is seen by the company as a currency that can be bought and sold. The paper concludes that Wattpad does not want to disrupt the publishing ecosystem because the values incorporated in the design of the platform are similar to the values of traditional publishers.
Keywords: publishing industry, self-publishing, online publishing, Wattpad, peer-to-peer platforms, values in design, online users
Public relations responsiveness during crime spikes: How and to what extent do social media and news-reporting exacerbate liquor-store thefts in Winnipeg?
Authors: MacKenzie Lindsay
Published: March 2022

For a period of approximately 18-months, the city of Winnipeg experienced an alarming spike in Liquor Mart thefts, that took a toll on the Winnipeg Police Service workforce because of the sheer number of investigations opened due to these crimes. Manitoba Liquor and Lotteries management were reeling from the impacts of these thefts on customers, employees, and their bottom line. Communications Director Andrea Kowall stated at a news conference on October 28, 2019, that she believed news reporting and social media posts by civilians were factors that contributed to the theft surges. This exploratory, single case study sought to examine how and to what extent social media and news reporting exacerbated liquor-store thefts at Liquor Marts in Winnipeg through the social phenomenon of theft and robbery crime spikes between August 31, 2018, and December 1, 2019. The social phenomenon provided an environment to analyze steps taken by policing organizations in situations impacting public safety. 
Interviews and a questionnaire were utilized to explore the Balance Zone Theory as it applied in this situational context. Crisis communications tactics such as social media were explored as well as testing for the presence of news waves by examining published articles in a chronological sequence. This case study could provide valuable insights to policing organizations implicated in media hypes when coupled with incidents of public interference in crime situations through the use of social media.  
Keywords: policing, crisis communications, balance zone theory, public relations, stealing thunder, news waves, social media
Insights of the role of estrogen in obesity from two models of ERα deletion
Authors: Saavedra-Peña Rocío del M , Taylor Natalia , Rodeheffer Matthew S
Published: March 2022

Sex hormones play a pivotal role in physiology and disease. Estrogen, the female sex hormone, has been long implicated in having protective roles against obesity. However, the direct impact of estrogens in white adipose tissue (WAT) function and growth is not understood. Here, we show that the deletion of estrogen receptor alpha (ERα; Esr1) from adipocytes using Adipoq-credoes not affect adipose mass in male or female mice under normal or high-fat diet (HFD) conditions. However, loss of ERα in adipocyte precursor cells (APs) via Pdgfra-cre leads to exacerbated obesity upon HFD feeding in both male and female mice, with s.c. adipose (SWAT)-specific expansion in male mice. Further characterization of these mice revealed infertility and increased plasma levels of sex hormones, including estradiol in female mice and androgens in male mice. These findings compromise the study of estrogen signaling within the adipocyte lineage using the Pdgfra-crestrain. However, AP transplant studies demonstrate that the increased AP hyperplasia in male SWAT upon Pdgfra-cre-mediated ablation of ERα is not driven by AP-intrinsic mechanisms but is rather mediated by off-target effects. These data highlight the inherent difficulties in studying models that disrupt the intricate balance of sex hormones. Thus, better approaches are needed to study the cellular and molecular mechanisms of sex hormones in obesity and disease.
H3N2 as the new influenza virus circulating in Brazil and the reflexes on Family and Community Health
Authors: Viana Lima Aline Milene , Araújo da Silva Ana Claudia , Pereira Martins Ana Suzane , de Sousa Bezerra Ana Victória , Silva Azevedo Bárbara Hellen da , Santos de Vasconcelos Soares Eveline Thomaz Moura , Freire Anastacio Fabiana , Fernandes de Queiroz José Leonildo , Torres de Amorim Josias Nelson , Pontes Nobre Juliana de , Carvalho Medeiros Juliany Narieza de , Mesquita Alvarenga Luanna Nayra , de Oliveira Lucas Borges , Pequeno de Melo Mariana , Costa Arruda Marina , de Souza Mauricio Caxias , Santos Martins Nara Franklin , Mendes Raquel Maia , Castro Monte Vanessa Silva de
Published: March 2022

The increase in cases of influenza virus infections in the last quarter of this year has drawn attention to an old acquaintance of humanity. The flu, as it is popularly called, has generated regional outbreaks across the country, driven by the introduction of a new strain of subtype A (H3N2), named Darwin. Currently, three types of influenza viruses are known: A, B and C. The first two are more likely to cause seasonal epidemics in different parts of the world, while the last one usually causes some milder cases. Type A influenza is classified into subtypes such as A (H1N1) and A (H3N2). Type B is divided into two lineages: Victoria and Yamagata. Although they have genetic differences, all types can cause similar symptoms, such as high fever, cough, sore throat, headaches, body and joint aches, chills and fatigue.
Critical healthcare for the elderly against COVID-19 : a multidisciplinary approach
Authors: Araújo da Silva Ana Claudia , Bomfim da Silva Ana Rosa , Pereira Martins Ana Suzane , da Silva Azevedo Bárbara Hellen , Santana de Queiroz Emília Natália , Moura Santos de Vasconcelos Soares Eveline Thomaz , Anastacio Fabiana Freire , Lopes Oliveira João Victor , Fernandes de Queiroz José Leonildo , Torres de Amorim Josias Nelson , Barros de Lima Joycilaine Beatriz , Pontes Nobre Juliana de , de Carvalho Medeiros Juliany Narieza , Nascimento Arrais Kaique Warley , da Silva Larissa Helena , de Sousa Magável Raulinho , de Melo Mariana Pequeno , de Souza Maurício Caxias , da Costa Nayara Ferreira , Santos Martins Nara Franklin , da Silva Nayra Cristina , Duarte Pordeus Pamella de Castro , Rebouças Leite Paula Andréa , Gomes Cardoso Thamyris Meygam , de Castro Monte Vanessa Silva
Published: March 2022

Objective: Describe critical health care for the elderly against COVID-19 in a multidisciplinary approach. Method: This is a qualitative study, with an exploratory documentary and detailed descriptive approach, with a bibliometric emphasis. Where several studies will be gathered for the characterization of each element present in their results. Results and discussion: Several studies were analyzed and discussed about the topics related to this study, they are: critical health care, health of the elderly, Covid-19 and multi disciplinary care. Scientific articles of national and international origin contributed effectively to the discussion of these results. Conclusion: This study achieved its objective, as it described critical health care for the elderly against COVID-19 in a multi disciplinary approach, it contributed satisfactorily to the entire academic community world wide, enabling the creation of new studies on this topic.
Dakwah Muhammadiyah Di-Era Digital Bagi Kalangan Milenial
Authors: Syarofah Alinda , Ichsan Yazida , Rahman Pathur , Kusumaningrum Hening , Nafiah Siti
Published: March 2022

Dakwah   di era   digital   memberikan dampak pada dunia dakwah saat ini, yakni memberikan  kemudahan, yang  akan  membuat batasan-batasan waktu dan jarak antar individu menjadi hampir tidak ada. Penelitian ini bertujuan untuk mengetahui bagaimana dakwah eksis di era milenial saat ini dengan perspektif Muhammadiyah, dan apa tantangan yang dihadapi. Perkembangan teknologi ini juga selaras dengan tujuan muhammadiyah yang menekankan Islam berkemajuan dalam dakwahnya. Hal yang dapat dilakukan Muhammadiyah sehingga dapat eksis di era milenial adalah melakukan penguatan amal usaha di bidang pendidikan atau lembaga sekolah maupun universitas; lalu memperkuat gerakan jamaah yang dimulai dari lingkungan keluarga yang memberikan arahan untuk menghadapi era saat ini; kemudian menggunakan perkembangan IT dalam menyajikan dakwah di era milenial; dan  saling bersinergi baik pimpinan maupun kader Muhammadiyah dalam memanfaatkan media sosial untuk menyebarkan gagasan tentang Islam dan kemuhammadiyahan. Sehingga para generasi milenial tertarik  dan dapat dengan mudah mengakses dakwah.
Optimalisasi Fungsi Tabung Wakaf Indonesia Dompet Dhuafa dalam Pengelolaan Wakaf Tunai
Authors: Rozalia Rozalia
Published: March 2022

Pada awalnya, perbincangan tentang wakaf kerap diarahkan kepada wakaf  benda tidak  bergerak seperti tanah, bangunan, pohon untuk diambil buahnya dan sumur untuk diambil airnya. Sedang wakaf benda bergerak baru mengemuka belakangan. Di antara wakaf benda bergerak yang ramai dibincangkan adalah wakaf  tunai (cash waqf) atau uang. Tabung Wakaf Indonesia (TWI) Dompet Dhuafa adalah salah satu lembaga yang    bergerak dalam  bidang sosial dan bertujuan meningkatkan kesejahteraan masyarakat dengan menggalang dan mengelola sumberdaya wakaf secara produktif, profesional dan amanah. Yang menjadi masalah dalam penelitian ini adalah bagaimana Fungsi Tabung Wakaf dalam Pengelolaan Wakaf Tunai? Apa faktor pendukung dan penghambat dalam pengelolaan wakaf tunai yang dilakukan olehTabung Wakaf Indoneia? Bagaimana upaya meningkatkan pengelolaan wakaf tunai di Tabung Wakaf Indonesia? Temuan penelitian ini adalah bahwa wakaf tunai memiliki kelebihan karena setiap orang bisa menyumbangkan hartanya tanpa batas-batas tertentu atau tanpa harus menunggu menjadi tuan tanah terlebih dahulu. Pemberian wakaf biasanya hanya dilakukan oleh orang-orang kaya dalam bentuk harta tidak bergerak, sedangkan sebagian besar masyarakat tidak mampu  berpartisipasi dalam kegiatan wakaf.
Tantangan dan Peluang Penyuluh Agama di Era Digital
Authors: Rahman Abdul
Published: March 2022

Di tengah pandemi covid 19 diperlukan keseriusan setiap pemangku kebijakan di negara ini dalam mengatasi wabah dan terus melakukan pembangunan. Sasaran utama pembangunan adalah pembangunan manusia, karena tanpa ada perubahan manusia pada dasarnya tidak ada pembangunan. Perubahan diri manusia dapat diharapkan antara lain karena adanya kegiatan penyuluhan, yang menimbulkan perubahan pengetahuan, ketrampilan, serta sikap. Penyuluhan salah satunya merupakan proses pengubahan perilaku dengan pendekatan komunikasi.  Sehingga penyuluh agama menguasai  komunikasi baik secara teori maupun secara praktiknya. Kemampuan komunikasi merupakan kompetesi dasar sebagai penyuluh agama yang profesional di era digital.
Kearifan Penyuluh Islam dalam Pluralitas Agama
Authors: Lutfi M
Published: March 2022

“Pluralisme” memandang kemajemukan secara positif-optimis dengan menerimanya     sebagai  kenyataan    dan    berbuat  sebaik  mungkin  berdasarkan kenyataan itu. Pluralisme tidak semata-mata menunjuk pada kenyataan adanya kemajemukan, tetapi juga keterlibatan aktif terhadap kemajemukan tersebut. Pluralisme agama dan budaya dapat  dijumpai dalam  kehidupan sehari-hari, baik di tempat kerja dan di kampus maupun di tempat pelayanan umum dan pusat-pusat perbelanjaan. Akan tetapi seseorang baru dapat dikatakan memiliki sifat “pluralis” apabila ia mampu berinteraksi secara positif dan toleran dalam lingkungan kemajemukan tersebut. Dalam Islam realitas pluralitas merupakan sesuatu fakta yang menyejarah, dan diakui sebagai bagian dari keanekaragaman manusia di muka bumi. Sehingga bisa dipastikan bahwa, tidak ada seorang pun yang boleh memaksakan sesuatu terhadap orang lain, termasuk dalam masalah keyakinan atau agama (baca antara lain : Qs. Al-Baqarah [2] : 256, Qs. Al-Kafirun [109] : 1-6). Tetapi yang dibutuhkan adalah “kearifan” dari masing-masing pemeluk agama, sehingga melahirkan “toleransi” dan “kedewasaan” dalam mengamalkan ajaran agama, atau dalam bahasa populernya “berdamai dengan perbedaan”. Penyuluh agama yang memiliki peran dan fungsi strategis dalam pembinaan kehidupan beragama bagi masyarakat seyogianya mempunyai kearifan itu, yang dapat dijadikan sebagai kekuatan dalam menyikapi dinamika kehidupan masyarakat beragama.
Adopsi Inovasi Komunitas Gerakan Pemuda Hijrah Terhadap Dakwah Online Pemuda Hijrah Shift Media
Authors: Ananda Talia Tri
Published: March 2022

Teknologi Komunikasi banyak mengalami kemajuan dari waktu ke waktu, termasuk saat ini perkembangan teknologi komunikasi melalui jaringan internet yang di dalamnya meliputi media sosial seperti youtube. Fenomena yang terjadi saat ini adalah adanya inovasi dakwah melalui media online yang salah satunya adalah akun youtube Pemuda Hijrah Shift Media. Penelitian ini dilakukan untuk mengetahui bagaimana pengalaman Komunitas Gerakan Pemuda Hijrah tentang pengetahuan, persuasi, keputusan, implementasi, serta konfirmasi dalam mengadopsi inovasi dakwah online Pemuda Hijrah Shift Media? Mengapa Komunitas Gerakan Pemuda Hijrah mengadopsi inovasi dakwah online Pemuda Hijrah Shift Media? Penelitian ini menggunakan metode fenomenologi dan pendekatan deskriptif kualitatif. Hasil penelitiannya adalah pengalaman Komunitas Gerakan Pemuda Hijrah  telah mengetahui akun youtube Pemuda Hijrah Shift Media melalui dua saluran komunikasi. Alasan Komunitas Gerakan Pemuda Hijrah mengadopsi inovasi dakwah online akun youtube Pemuda Hijrah Shift Media adalah karena akun youtube Pemuda Hijrah Shift Media memiliki kesesuaian dan memberikan keuntungan kepada Komunitas Pemuda Hijrah.
Hadis dan Analisis Aliran Politik Rijal: Studi Geo-Politik Terhadap Aliran Shi‘ah dan Nasb
Authors: Abdul Kodir Aceng
Published: March 2022

This article tries to trace and explain the relation between “the political movement” and “the hadith movement” in the first three centuries of Islam, particularly in Shi‘ah and Nasb sectes. This research uses historical and geo-political approaches in analyzing the transmission of hadith conducted by these two sectes. This article shows that the transmitters of hadith who supported ‘Ali were mostly in Kufah, while those who hated ‘Ali (Nasb) were in Damascus
Membumikan Teks Agama Ala Nahdlatul Ulama
Authors: Rosyidi Muhib
Published: March 2022

This article discusses how Bahtsul Masail Institution in Nahdlatul Ulama uses religious texts – the Qur’an and Hadith – independently from the socio-historical context of Muslim community in Indonesia. The main source of this research is Ahkamul Fuqaha: Solusi Problematika Hukum Islam, Keputusan Muktamar, Munas dan Konbes Nahdlatul Ulama (1926-2004). The article finds that as the followers of Shafi‘ites, NU’s treatment with the text of al-Qur’an and Hadith within local tradition has its own characteristics, in some way differ themselves with the Shafi‘ites as a sect. In fact, NU is more likely prefer the local traditions of Muslim society than the religious texts themselves.
Negara Islam Indonesia: Konsepsi Shajarah Tayyibah dalam Konstruk Negara Islam
Authors: Hadi Syofyan
Published: March 2022

This article aims to prove that the interpretation of the verses of the Qur’an by using a rational approach to the political vision has a tendency to release an understanding of the text from its real context. This often makes an interpretation of these verses that are interpreted to justify and legalize the ideology that is being held. Based on the study of the works of supporters and leaders of the Negara Islam Indonesia (NII), this study proves that their interpretation is so far detached from the historical context of the Qur’an. More than once, the article insists, one verse is interpreted too far to legalize their aspiration without giving any reference to the traditions which are related to the context of the Qur’an, and the opinions of the previous ‘ulama’ and interpreters of the Qur’an, who are considered more authoritative in giving an interpretation to the verses of the Qur’an.
Hak-hak Perempuan dalam Pernikahan Perspektif Tafsir Sufistik: Analisis terhadap Penafsiran Al-Alusi dan ‘Abd al-Qadir al-Jilani
Authors: Kaltsum Lilik Ummi
Published: March 2022

The major problem discussed in this article is the presence of domestic violence conducted by husbands towards their wives in their marriages. Several verses of the Qur’an have been used to legitimize these arrogant actions. Using religious texts and culture of patriarchy, domestic violence seems to persist. This article discusses the interpretation of some verses of the Qur’an, especially the mystical interpretation, which is related to the rights of wives in marriage. Two mystical interpretations are the case of the study, i.e., Ruh al-Ma‘ani of al-Alusi and al-Fawatih al-Ilahiyya of al-Jilani. This article describes analytically and critically explores the ideas of al-Jilani and al-Alusi about women’s rights in Islam.
Pertalian Angka dan Makna dalam Al-Qur’an Mempertemukan Relasi Antarayat dalam Kajian al-I‘jaz al-‘Adadi dan Kajian Tafsir al-Qur’an bi al-Qur’an
Authors: Rohman Izza
Published: March 2022

This paper looks into intra-Qur’anic connections derived from serious efforts either to reveal what-so-called the mathematic miracle of the Qur’an or to interprete the Qur’an with the Qur’an. In doing so, it seeks to explore the compatibility of the two as well as the possibility to make both approaches to the Qur’an mutually inclusive. In this regard, this article deals particularly with some examples of connection among Qur’anic verses pursued through various attempts to find the alleged numerical code in the Qur’an, and compares them to what selected tafsirs have disclosed.
Kesejarahan al-Qur’an dan Hermeneutika
Authors: Abdullah Mudhofir
Published: March 2022

The Qur'an is not sufficient to be read in a single glass. Its significance continues to be present in a tumult of life. The Qur'an is also a book that concerns with human affairs and the environment. Because of its importance of the position, the Qur’an needs to be understood with intelligent and open perspectives. The more intelligent and open in reading the Qur'an, the meaning of the Qur’an will be more intelligent and open. Conversely, the more narrow and closedin reading the Qur'an, the meaning will be more narrow and closed. Therefore the readers of the Qur’an are encouraged to continue improving their capacity to understand the Qur'an very well. To master not only the basic sciences, but also other sciences related to the growth of human civilization. That is why a new method to read the Qur’an, such as hermeneutics and the historicity of the Qur’an, may, within certain limits, embrace the presence of al-Qur'an in life.
Konsep Kesatuan Tema al-Qur’an Menurut Sayyid Qutb
Authors: Mulazamah Siti
Published: March 2022

This article is to prove that the more comprehensive the interpretation of the Qur’an is the more objective his/her interpretation is. This article demonstrates that Sayyid Qutb is one of the mufassirs who interprets the Qur’an comprehensively. The concept offered by Qutb is the thematic unity of the Qur’an. Qutb’s interpretation is based on the thematic unity in the Qur’an as a whole and in its each Sura. This article agrees with Muhammad ‘Abd Allah Diraz, A.H. Mathias Zahniser who argue for the harmony, coherence and thematic unity of the Qur’an. However, it argues against ‘Izzuddin ibn ‘Abd al-Salam, Subhi al-Salih, and Salwa M.S. El-Awa who doubt and deny the harmony, coherence and thematic unity of the Qur’an.