bluuebunny/crossref_metadata_2025 huggingface dataset:
Study the Role of Cell Free DNA in the Diagnosis of Hepatocellular Carcinoma, an Egyptian Study
Authors: Radwan Noha Hassan , Abdelkhalik Hadeer Ali , Elgayar Dina Farouk , Elsharkawy Marwa Mahmoud
Published: April 2022

Background and objective: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Since the conventional tissue biopsy and AFP have limited value, a new promising diagnostic method” liquid biopsy” has emerged. Cell free DNA is one of the liquid biopsy corner stones along with circulating tumor cells. Aim of the work: The study aims to evaluate the role of cf-DNA in the prediction of HCC. Subjects and methods: Eighty newly diagnosed HCC cases and seventy seven apparently healthy individuals were recruited from the National Cancer Institute, Cairo University. Cf-DNA level is measured by Qubit fluorometer assay and AFP was measured by ELISA for control. Comparisons between quantitative variables were done using the non-parametric Kruskal-Wallisand Mann-Whitney. Correlation between quantitative variables were done using Spearman correlation coefficient and a ROC curve was constructed with area under curve analysis performed to detect best cut off value of cf-DNA and AFP for detection of HCC. Results: The median cf-DNA and AFP levels were statistically significant higher in HCC patients (0,11ng/µl and 160.9 ng/ml respectively) than in control group (0.04 ng/ µl and 1.30 ng/ml respectively). Upon plotting ROC curve, cf-DNA and AFP gave a sensitivity of 78% and 93.7% respectively, a specificity of 59.7% and 92.2% respectively. The diagnostic value of cf-DNA in combination with AFP level has slightly improved the specificity (96.1%) on the expense of the sensitivity which was decreased (69.5%). Conclusion: Cf-DNA plays a role in the prediction of HCC but still AFP has the upper hand in the diagnosis of HCC in Egyptian population. Liquid biopsy still hasits own limitations. The techniques of colleting’ liquid”, and detection of cf-DNA must be standardized.
Cigarettes Smoking Pattern in Patient with Urothelial Carcinoma of the Bladder after Smoking Cessation in Tertiary Hospital
Authors: Novesar Aidil Rahman , Pramod Sawkar Vijay , Safriadi Ferry
Published: April 2022

Background: Urothelial carcinoma is the most widely recognized histologic type of bladder cancer. Smoking duration and intensity associated with tumour aggressiveness and recurrence. This study aims to examine smoking behavioural change in patients with bladder urothelial carcinoma who were given an intervention for smoking cessation. Methods: A cross-sectional study (2009 – 2019) was conducted. Subjects were divided into three groups: patients who had smoked <20 cigarettes per day for ≤30 years; patients who had smoked for 31–40 years or had smoked >20 cigarettes per day for ≤30 years; and patients who had smoked for >40 years. General characteristics, educational level and quit levels are noted. These data were obtained from the medical record and anamnesis by telephone. Result: A total of 325 patients with urothelial cancer between 2009-2019 were involved. 273 (84%) patients were male, aged 58.71 ± 12.8 years. 40.9% had a history of smoking for >40 years, 66.5% of patients did not quit smoking at all. There was a significant difference in smoking cessation rates between groups with a history of different smoking intensities (p = 0.000). Mann-Whitney U test showed that there was a significant difference between the group who had a history of smoking <20 cigarettes for ≤30 years and the group who smoked for 31-40 years or >20 cigarettes per day for ≤30 years with the group who smoked for >40 years (p = 0.000 on both comparisons). 135 (41.5%) patients were in the lower education group.Conclusion: The patient’s history of heavy smoking intensity and lower educational level was associated with a lower likelihood of smoking cessation. Urologists must play an important role in the education and intervention process to support patients to quit smoking. A guide/guideline is needed and it could be through a special smoking clinic for counselling or treatment.
GIS to Explore the Geographical Mysteries of Oral Cancer: Geospatial Distribution of Patients Diagnosed with Oral Potentially Malignant Disorders at the University Dental Hospital Peradeniya
Authors: Athukorala Isuru , Medawela R.M.S.H.B , Gunawardana Malika , Jayasinghe R.D.
Published: April 2022

Background: Oral cancers which are often preceded by an oral potentially malignant disorder (OPMD) carries the highest mortality rate among all cancers in Sri Lanka. Dental Teaching Hospital, Peradeniya is one of the tertiary centres in Sri Lanka for treating OPMD with a high patient turnover. Objectives: This study aimed to determine the geospatial distribution of OPMD patients who attended Dental Hospital, Peradeniya (DHP) using geocoding methods. Materials and Methods: A retrospective study was done by obtaining data of 869 OPMD patients who visited DHP within the last 4 years to geo-code their addresses using GIS software. Results: The majority of the sample consisted of oral lichen planus (OLP) (52.47%). 29% and 18.64% of the patients were diagnosed with leukoplakia and oral submucous fibrosis (OSF) respectively. Most of the OPMD patients (60.64%) who visited the clinic were from the Kandy district and surprisingly the majority of OPMD patients had been reported from non-estate areas. The second and third highest number of patients were respectively from Nuwaraeliya (11.28%) and Kegalle (7.48%). More than half (57.19%) of the patients were living within 20 km of the hospital. Conclusion: The composition of patients with OPMDs visited the DHP had deviated from the national data. More than half of the sample residing within a reasonable travel distance to a specialist care centre.
Patterns of Failure in Node Positive Cervical Cancer Patients Treated with Radical Radiotherapy
Authors: Muttath Geetha , Keloth Erakkotan Greeshma , Narayanan Vinin , Jones Joneetha , Narendran Arun. P. , Yahiya Nabeel , Suresh Akhil. P. , Minhaj Muhammed , Riyas Muhammed
Published: April 2022

Background: Chemoradiation plays an important role in cervical cancer treatment but dose to organs at risk (OAR) is the limitation while escalating dose to target. With conformal techniques dose escalation is made possible without increase in toxicities. Though node positive cervical cancers have poorer prognosis delivering higher dose to the involved nodes have shown benefit. We aim to determine the patterns of failure in node positive cervical cancer patients treated with chemoradiation and to determine the grade III and IV toxicities associated with it.Methods and Materials: In this retrospective study node positive cervical cancer patients treated with conformal radiotherapy were analysed. 45 Gy -50.4 Gy was given to the pelvis and 55 Gy to positive nodes with sequential or simultaneous integrated boost (SIB) in 25 -28 fractions with weekly cisplatin 40mg/m2 followed by brachy therapy. Extended fields were used to treat patients with positive para aortic lymph nodes. Treatment toxicities were recorded as per CTCAE version 4.3. Results: Of the 62 patients 87.1% had squamous cell carcinoma and majority were in stage II (38.7%). At a median follow up of 33 months two (3.2%) patients had local recurrence, eight (12.9 %) had distant failure and one (1.6%) had loco regional recurrence. Lung was the most common site of metastasis followed by the supraclavicular region. The 3 year overall and disease free survival were 91.4 % and 77.2 % respectively. Stage of the disease (p=0.001) and residue at the end of therapy (p-0.010) showed significant association with DFS but not with OS. 21 (33%) had Grade III –IV toxicities, nine (13%) having acute toxicities and 12 (19.4%) had late toxicities. Conclusion: Though node positive cervical cancers have poor prognosis our study showed that aggressive management improves the outcome without increase in toxicities.
Dosimetric Analysis and Effect of Different Definitions of Prescription Point “A” to OAR in High Dose Rate Brachytherapy for Cervical Cancer
Authors: Agrawal Shivangi , Gupta Shivani , Stephen PS Meenu , Gothwal Ravinder Singh , Meena Ramraj , Meena Chetna , Kakkar Abhinav
Published: April 2022

Purpose: Dosimetric analysis and effect of different definitions of prescription point “A” to OAR in high dose rate brachytherapy for cervical cancer. Methods and Materials: This retrospective comparative dosimetric study is based on the data of 25 patients with histologically proven cervical carcinoma treated with HDR (high-dose-rate) brachytherapy. Patients received 21 Gy in three fractions (7.0 Gy X three fractions) to point A (AMAN, revised Manchester definition). Further, the patients were replanned with the new point A (AABS) as per the American Brachytherapy Society/ICRU 89 which is defined on CT images. The data compiled was then compared with the data observed from point A (AMAN). Results: When AMAN normalization method was used, the mean dose to the bladder at 0.1cc, 1cc, 2cc and 5cc obtained was 1121.2±54.5, 1058.7±44.1, 875.0±38.6, 780.5±35.9, and 641.2±29.5 cGy respectively. Likewise, using the ICRU-89 point A (ABS) normalization method, the mean dose to 0.1 cc, 0.2 cc, 1 cc, 2 cc, and 5cc bladder volumes was 1178±156.1,1110.0±130.8, 921.6±111.4, 826.6±101.32, and 673.3±80.9 cGy, respectively. For the rectum, point A (MAN) normalization plans, the mean dose of 0.1 cc, 0.2 cc,1 cc, 2 cc, and 5cc rectum volumes was 680±143.5, 652.53±129.8,574.25±131.1, 530±126.9, and 452.5±121.2cGy, respectively. Likewise, using the A (ABS) plan, the mean dose of 0.1 cc, 0.2cc, 1 cc, 2 cc, and 5cc rectum volume was 707.5±148.1, 678.7±128.7, 596.2±135.6, 551.25±127.44 and 471.25±122.64 cGy respectively. The statistical mean difference of Total Reference Air Kerma rate, V100 (cc), bladder, and rectum, was found significant. Conclusion: The present study attempts to analyze the differences in rectum and bladder dose, as well as the size of the volume enclosed for prescribed Isodose curve following ICRU 38 and ABS-ICRU 89 recommendations about intracavitary cervix cancer treated with brachytherapy. With Manchester system being more static, i.e., lesser variation with geometric changes, it is preferable in comparison to ABS system.
Première table ronde : « Être une juridiction financière à l’horizon 2025 »
Authors: Groper Nicolas
Published: April 2022

Le régime unifié de responsabilité des gestionnaires publics prévu pour 2022, et qui sera mis en œuvre par la Cour des comptes, s’inscrira en continuité avec le régime aujourd’hui sanctionné par la Cour de discipline budgétaire et financière (CDBF), dont les infractions et la jurisprudence constitueront le socle.
La nouvelle responsabilité des ordonnateurs devant la juridiction financière : plus de moyens, mais encore modeste
Authors: Pierucci Christophe
Published: April 2022

La loi de finances pour 2022 a habilité le Gouvernement à agir par voie d’ordonnance pour réformer la responsabilité des ordonnateurs. En exigeant que la répression des fautes de gestion soit confiée à la Cour des comptes au lieu de la CDBF, elle apporte une louable réponse à l’insuffisance des moyens du juge des ordonnateurs depuis 1948. La responsabilité répressive des ordonnateurs est-elle pour autant en mesure de connaître un réel essor et de devenir moins confidentielle ? Les principes essentiels définis par la loi affaiblissent la portée du futur régime de responsabilité et le vouent à demeurer modeste, même si certains facteurs d’équilibre peuvent être envisagés.
La Cour des comptes et l’assistance au Parlement
Authors: Camby Jean-Pierre
Published: April 2022

La position institutionnelle de la Cour des comptes, la diversité de ses travaux, l’extension des procédures notamment marquée par la LOLF et, plus récemment, à l’Assemblée nationale par le « Printemps de l’évaluation » ont établi une relation constante entre la Cour et le Parlement. Au-delà de la fiabilité et de la rapidité de cette expertise, la multiplicité des sujets traités nourrit la mission d’évaluation des politiques publiques qui incombe au Parlement.
L’hypothèse d’un référendum révocatoire des décideurs publics locaux en matière financière
Authors: Bahougne Louis
Published: April 2022

Les élus locaux qui ont la qualité d’ordonnateur de leur collectivité sont habituellement exclus des mécanismes répressifs de mise en cause de la responsabilité financière des gestionnaires publics. Dans le même temps, le droit interne ne fournit pas de mécanismes efficaces de mise en cause de leur responsabilité politique. C’est dans ces conditions qu’est formulée l’hypothèse d’un référendum révocatoire des décideurs publics locaux en matière financière.
Les questions citoyennes devant les juridictions financières
Authors: Bezzina Anne-Charlène
Published: April 2022

La « question citoyenne de constitutionnalité », comme l’écrit le président Laurent Fabius pour fêter les dix ans de la question prioritaire de constitutionnalité, devant les juridictions financières est un vaste sujet, celui d’une rencontre contrariée entre le droit constitutionnel et le contentieux financier. Pourtant, depuis cette instruction, le constat est sans conteste celui d’une faible appropriation de la QPC par les juridictions financières. Néanmoins, malgré l’intérêt relatif et l’absence de spécificité des apports de la question financière au contentieux de constitutionnalité, il nous apparaît que la rencontre de la QPC et des juges financiers est immanquable et la présente contribution formulera des observations pour leur meilleure articulation. La question de l’appropriation citoyenne de la QPC en matière financière n’est pas dépourvue d’intérêt puisqu’il apparaît qu’en dix ans, les spécificités du contentieux financier ont été saisies par les justiciables et ont pu faire l’objet de précisions constitutionnelles utiles. Pour étudier la question de l’appropriation citoyenne de la QPC par les juridictions financières il sera intéressant d’utiliser les « trois E »: l’efficacité, l’efficience et l’économie.
BENEFÍCIOS DO KINESIO TAPING NO CONTROLE DA DOR E NA QUALIDADE DE VIDA DE INDIVÍDUOS QUE APRESENTAM A SÍNDROME DA DOR SUBACROMIAL – REVISÃO BIBLIOGRÁFICA DA LITERATURA
Authors: Silva Joriana Tayrine Lima da , Souza Nayara Umbelina de , Lima Tatiely Marinho da Costa
Published: April 2022

RESUMO

Introdução: A síndrome do impacto do ombro é uma patologia inflamatória que ocorre por compressão mecânica das estruturas do espaço subacromial. A kinesio taping consiste em uma fita elástica adesiva, que dentre outros benefícios, ajuda a diminuir o impacto sobre as articulações. Objetivo: Verificar, através de uma revisão bibliográfica, se o uso do kinesio taping em indivíduos com síndrome do impacto do ombro pode trazer melhoras, tanto no controle da dor, quanto na qualidade de vida dessas pessoas. Metodologia: Este artigo refere-se a uma revisão integrativa da literatura. A busca foi realizada na Biblioteca Virtual em Saúde, SciELO, COCHRANE and PUBMED. Foram incluídas pesquisas que analisaram o uso do kinesio taping em indivíduos com síndrome do impacto do ombro, sendo artigos publicados nos últimos 10 anos, nas línguas inglesa e portuguesa. Resultados: Após a aplicação dos critérios de inclusão e exclusão, permaneceram apenas 11 artigos para análise, entre os anos de 2011 a 2019. Observou-se que estes estudos mostraram vantagens no uso do kinesio taping, como o controle da dor nessa síndrome, porém evidenciaram que sozinho, não dá ao paciente melhores resultados para se manter uma qualidade de vida. Conclusão: O kinesio taping é uma técnica excelente para quem tem essa síndrome dolorosa, porém é importante associar a outras técnicas. Dessa forma conclui-se que o kinesio taping pode ser uma alternativa e/ou suporte para esse tipo de síndrome dolorosa.

Palavras-chaves: Bandage AND shoulder pain; Kinesio taping AND shoulder pain; Kinesio taping; Kinesio taping shoulder; Kinesio taping AND impingement syndrome.
Acetazolamide to treat symptomatic ruptured arachnoid cysts: illustrative cases
Authors: Watson Isabella , McDonald Patrick J. , Steinbok Paul , Graeber Brendon , Singhal Ashutosh
Published: April 2022

BACKGROUND

Arachnoid cysts are benign, often asymptomatic intracranial mass lesions that, when ruptured, may cause seizures, raised intracranial pressure, hemorrhage, and/or loss of consciousness. There is no widely agreed upon treatment, and there is debate as to whether a nonoperative or surgical approach is the best course of action. The carbonic anhydrase inhibitor acetazolamide may be an effective nonoperative approach in treating ruptured arachnoid cysts.

OBSERVATIONS

The Pediatric Neurosurgery Clinical Database at BC Children’s Hospital from 2000 to 2020 was queried, and four pediatric patients who were treated with acetazolamide after presentation with a ruptured middle cranial fossa arachnoid cyst were identified. All patients showed some degree of symptom improvement. Three of the patients showed complete reabsorption of their subdural collections in the ensuing 6 months. One patient had an inadequate response to acetazolamide and required surgical management.

LESSONS

Acetazolamide is a safe and reasonable primary treatment option in pediatric patients with ruptured middle cranial fossa arachnoid cysts, and it may help avoid the need for surgery.
Role of electromyography and ultrasonography in the diagnosis of double crush lumbar radiculopathy and common fibular injury: illustrative cases
Authors: Shields Lisa B. E. , Iyer Vasudeva G. , Harpring John E. , Rao Abigail J. , Zhang Yi Ping , Shields Christopher B.
Published: April 2022

BACKGROUND

Double crush syndrome consists of two compression sites along a peripheral nerve and is rare in the lower extremities. Electrodiagnostic and ultrasound (US) studies may be helpful in evaluating foot drop involving overlapping pathologies.

OBSERVATIONS

Case 1 involved a man who presented with left dorsiflexor weakness and left foot numbness. Electromyography (EMG) revealed a left common fibular nerve entrapment neuropathy and left L5 radiculopathy. US and magnetic resonance imaging (MRI) revealed a large cystic lesion of the left common fibular nerve treated by cyst removal. The left foot drop persisted postoperatively. Lumbar computed tomography myelography revealed severe left foraminal stenosis at L5–S1. Multilevel lumbar laminectomies and facetectomies with an L5–S1 fusion were performed. Within 1 month postoperatively, the left foot drop had improved. Case 2 involved a man who developed a right foot drop caused by right lumbar foraminal stenosis at L4–5 and L5–S1. EMG and US of the right common fibular neuropathy showed large fascicles involving the right common fibular nerve. MRI revealed a hyperintense signal of the right common fibular nerve. Spontaneous improvement occurred within 6 months without surgery.

LESSONS

Spine surgeons should recognize double crush in the lower extremities. EMG and US are valuable in detecting peripheral nerve abnormalities, especially in cases with overlapping lumbar pathology.
Meningioma with holo-sagittal sinus involvement treated successfully with intrinsic sinus surgery: illustrative case
Authors: Rajagopal Megan , Toms Jamie , Graham R. Scott
Published: April 2022

BACKGROUND

This report describes an unusual meningioma with a large left frontal component and extensive growth within the sagittal sinus and its successful treatment with a staged approach: left frontal craniotomy followed by a sagittal craniotomy and intrinsic removal of the tumor from the sagittal sinus.

OBSERVATIONS

A previously healthy 27-year-old presented with 6 months of progressively worsening bilateral headaches, visual changes, and nausea. On examination she had a left cranial nerve VI palsy and severe papilledema. Magnetic resonance imaging revealed a 5.1 × 3.8 × 4.1 cm homogenously enhancing left superior frontal parafalcine extra-axial mass with surrounding vasogenic edema and growth through the sagittal sinus extending just short of the torcula.

LESSONS

This case report describes a fast-growing meningioma with a unique pattern of spread, growing through the sagittal sinus as if it were a conduit and resulting in complete occlusion of flow in the sinus. An important recognition in this case was that a robust parasagittal venous plexus had developed on either side of the falx cerebri with drainage to the inferior sagittal sinus. This collateral drainage pattern allowed for an extradural opening of the sagittal sinus from front to back and intrinsic resection of the tumor from the sinus with preservation of the lateral walls of the sinus.
Trigeminal neuropathy after tozinameran vaccination against COVID-19 in postmicrovascular decompression for trigeminal neuralgia: illustrative case
Authors: Onoda Keisuke , Sashida Ryohei , Fujiwara Ren , Wakamiya Tomihiro , Michiwaki Yuhei , Tanaka Tatsuya , Shimoji Kazuaki , Suehiro Eiichi , Yamane Fumitaka , Kawashima Masatou , Matsuno Akira
Published: April 2022

BACKGROUND

Vaccines against coronavirus disease 2019 have a high level of efficacy and safety across all populations. However, numerous case series have been published on neurological disorders, including Bell’s palsy, Guillain-Barre syndrome, transverse myelitis, and multiple sclerosis. The authors presented a case of trigeminal neuropathy after coronavirus vaccination in a patient who had undergone microvascular decompression (MVD) for trigeminal neuralgia (TN).

OBSERVATIONS

A 77-year-old woman presented with acute trigeminal neuropathy after receiving a Pfizer-BioNtech vaccination (tozinameran) against severe acute respiratory syndrome coronavirus 2. The patient had undergone MVD for TN and the facial pain completely disappeared. One month later, she received the first injection of the tozinameran vaccine. Twelve hours after vaccination, she presented with numbness and pain induced by touching any place on the entire right face. No eruption was observed on her face. The serum herpes zoster virus antibodies were confirmed within the normal range. Magnetic resonance imaging revealed no abnormalities. The authors suspected a right trigeminal neuropathy after vaccination. Administration of carbamazepine and pregabalin improved TN but facial numbness persisted, especially in the mandibular division.

LESSONS

The coronavirus is a possible etiology of secondary trigeminal neuropathy in the case of MVD for TN.
Undifferentiated presentation of unilateral agenesis of a cervical pedicle and a contiguous vertebral hemangioma: illustrative case
Authors: Alsuwaihel Mosaab , El-Mughayyar Dana , MacLennan Matthew , Attabib Najmedden
Published: April 2022

BACKGROUND

Unilateral agenesis of a cervical pedicle is a known rare entity that has been well described over the past 70 years. It is usually an incidental or minimally symptomatic presentation with no significant clinical repercussion. No previous report has described concurrent non-osseous developmental abnormalities alongside this unique pathology.

OBSERVATIONS

This case reported a cervical hemangioma with associated unilateral pedicle agenesis and an incidental finding of callosal dysgenesis and lipoma. The initial presentation consisted solely of persistent neck pain, with cervical radiography illustrating significant kyphotic deformity secondary to apparent anterolisthesis of C3-C4. The patient underwent a combined approach: anterior cervical corpectomy at C4-C5 with supplemental posterior fusion. The authors provided a review of the literature concerning developmental pedicle abnormalities and vertebral hemangioma. Pedicle agenesis is known to be associated with multiple pathologies, but the authors have not found evidence of a clinical paradigm consisting of a vertebral hemangioma in the presence of cervical pedicle agenesis, callosal dysgenesis, or callosal lipoma.

LESSONS

Careful evaluation of radiographs with appropriate subsequent multimodal imaging is key to identifying unique pathologies in the spine that complement a patient’s history and clinical findings. If multiple abnormalities are noted, a novel clinical etiology or syndrome must be considered.
Long-term progression-free survival achieved in the skull base metastasis of gastrointestinal stromal tumor with introduction of tyrosine kinase inhibitor: illustrative case
Authors: Kawanishi Akiya , Umekawa Motoyuki , Miyawaki Satoru , Fujitani Shigeta , Ishizawa Takeaki , Ushiku Tetsuo , Hongo Hiroki , Teranishi Yu , Shojima Masaaki , Shin Masahiro , Hasegawa Kiyoshi , Saito Nobuhito
Published: April 2022

BACKGROUND

Gastrointestinal stromal tumors (GISTs) are common subepithelial tumors that rarely metastasize to the intracranial space. Because the standard treatment for metastatic intracranial GISTs has not been established, multimodal therapies are needed, especially in the case of skull base metastasis. However, its outcome has not always been favorable. The authors report the longest known surviving case of skull base metastasis of GIST treated with imatinib only.

OBSERVATIONS

A 52-year-old male with a history of GIST presented with left facial swelling and numbness. Examinations revealed a 70-mm tumor occupying the left middle cranial fossa and the orbit. The authors performed transnasal endoscopic tumor biopsy for definitive diagnosis and reintroduced imatinib treatment. The tumor significantly decreased in size early after the introduction of imatinib, and symptoms completely disappeared within several weeks. The lesion has remained shrunk radiologically for 63 months, and the patient is continuously being followed up under imatinib treatment.

LESSONS

The authors reported a rare case of skull base metastasis of GIST successfully treated solely with systemic therapy with a tyrosine kinase inhibitor, achieving tumor control for over 5 years. This case suggests that tyrosine kinase inhibitors might play a key role in the multidisciplinary treatment for skull base metastases of GIST.
Оцінка рівня фізичного розвитку студенток за антропометричними ознаками
Authors: Марчик Валентина Іванівна
Published: April 2022

Порівнювали суб'єктивні відчуття втоми у студенток з рівнем їх фізичного розвитку, який обчислювали за формулою Дубогай. Виявилено, що в групі "не відчуваю втоми" відстутні досліджувані з низьким рівнем фізичного розвитку.
Комунікативні здібності як показник соціального здоров’я у студентів різних спеціальностей
Authors: Марчик Валентина Іванівна , Переверзєва Світлана Василівна
Published: April 2022

В роботі визначали особливостей розвитку комунікативних здібностей майбутніх педагогів за різними спеціальностями за допомогою анкети «Методика виявлення комунікативних здібностей», що вміщує 20 запитань. Дослідження комунікативних здібностей як показника соціального здоров’я студентів, які набувають професію педагога, виявило середній, вище за середній і високий рівні їх розвитку у переважної більшості першокурсників. Встановлено, що студенти вищого навчального закладу спеціальності «фізична культура» мають кращі показники розвитку комунікаційних здібностей, ніж студенти спеціальності «біологія, хімія». Спортивна діяльність створює умови, які спрямовані на стимуляцію вільного висловлювання і мовлення, умінь спілкування, що віддзеркалюється в ефективному розвитку комунікативних здібностей особистості.
Адаптація молодших школярів в умовах негативного екологічного впливу
Authors: Марчик Валентина Іванівна , Шутько Віктор Васильович
Published: April 2022

В досліджені адаптації молодших школярів в умовах негативного екологічного впливу за модифікованою формулою Баєвського, пристосованою для учнів початкової школи встановлено, що стан адаптаційного потенціалу школярів 1 класу відповідає незадовільному рівню, школярів 2 класу – напруженому рівню і школярів 3 класу – задовільному. Виявлена позитивна динаміка зростання адаптаційних можливостей школярів молодших класів від першого до третього класу.
Теоретико-методичні засади навчання фонетики української мови в гімназії : дисертація на здобуття наукового ступеня доктора педагогічних наук
Authors:   , Бакум Зінаїда Павлівна
Published: April 2022

У дослідженні уточнено зміст й розроблена ефективна методика навчання фонетики в гімназії.
Компоненти здоров’я першокурсників ЗВО в цілісній моделі
Authors: Марчик Валентина Іванівна
Published: April 2022

Дослідження компонентів здоров’я студентів І курсу ЗВО показало, що фізичне здоров’я в цілісній моделі складає 36%, психічне здоров’я – 34%, а моральне здоров’я – 30%. Комплекс заходів спрямований на підвищення рівня морального (соціального) здоров’я буде сприяти підвищенню ефективності процесу укріплення здоров’я.
Діагностика навчально-пізнавальної діяльності студентів методом тестування
Authors: Щербина С. М. , Щербина І. Ю.
Published: April 2022

У статті визначено місце діагностики в системі педагогічного моніторингу, представлено досвід використання тестування як методу контролю й оцінювання результатів навчально-пізнавальної діяльності студентів.
Формування активної професійної позиції майбутніх педагогів засобом використання інтерактивних методів навчання у процесі вивчення педагогічних дисциплін
Authors: Щербина С. М. , Щербина І. Ю.
Published: April 2022

У статті розкрито особливості формування активної професійної позиції майбутніх педагогів засобом використання інтерактивних методів навчання у процесі вивчення педагогічних дисциплін.
Державна соціальна політика та розвиток соціальної освіти: зарубіжний досвід та вітчизняний контекст
Authors: Дороніна Т. О.
Published: April 2022

У статті розглядається питання впливу соціальної державної політики на розвиток структури та змісту підготовки соціального працівника в Україні та в світі. Констатовано, що характерною рисою сучасного розвитку соціальної сфери держави є її залежність від економічного розвитку, який, за твердженням сучасних науковців, аналітиків та експертів, знаходиться в кризовому стані. Розрив між декларованими на державному рівні цінностями соціального плану та реальними потребами населення у соціальному захисті актуалізує проблему готовності соціальних працівників до викликів сучасності. На основі аналізу сучасного стану соціальної політики України, з огляду на чинну систему підготовки соціальних працівників у вітчизняних закладах вищої освіти та провідні напрями вітчизняних досліджень зарубіжного досвіду з визначеної проблеми, зроблено висновок щодо необхідності суттєвої розробки проблеми співвіднесення чинних (світових) моделей соціального захисту населення із особливостями підготовки соціальних працівників з огляду на вітчизняний контекст.
Особистісно орієнтоване навчання як чинник стимулювання творчої активності студентів
Authors: Білоус О. С.
Published: April 2022

У статті обґрунтовується необхідність модернізації підготовки кадрів в умовах вищої школи. Aкцент робиться на особистісно орієнтованому навчанні як чиннику стимулювання творчої активності студентів, їх готовності до творчої професійної діяльності.
Про рівень сформованості творчої активності в студентів музично-педагогічних факультетів педуніверситету різних курсів навчання
Authors: Білоус О. С.
Published: April 2022

В статье представлены результаты экспериментального исследования уровней сформированности творческой активности у студентов музыкально-педагогических факультетов педуниверситетов.
Формування творчої активності студентів у процесі навчання предметам музичного циклу
Authors: Білоус О. С.
Published: April 2022

У статті розглядається проблема формування творчої активності студентів у процесі навчання предметам музичного циклу, розкривається зміст програми навчання музичним дисциплінам, етапи її реалізації в ході формуючого експерименту.
Інноваційні форми методичноі роботи як засіб формування професійних вмінь молодого вчителя
Authors: Волощук І. А.
Published: April 2022

У статті розглядаються форми методичної роботи як основні складові компоненти формування готовності молодого вчителя до інноваційної діяльності.
IT - Based Mathematics Learning Module To Decrease Students’ Mathematical Anxiety
Authors: Istikomah Endang , Herlina Sari , Nurmaliza Nurmaliza
Published: April 2022

The purpose of this study was to determine the level of students' mathematics anxiety and student learning outcomes after using the PMB IT module. The type of this research is Pre-Experiment with One Group Pretest-Posttest design. The instruments used are student mathematics anxiety questionnaire sheets and student response questionnaires, while student learning outcomes can be seen after the UAS exam. The data analysis technique used is qualitative and quantitative data analysis. For data processing, the writer used SPSS 16 software and Microsoft Excel 2013. The students' mathematical anxiety data obtained were analyzed descriptively and student learning outcomes data were processed using Inferential Statistics One-Sample T-Test. The results showed that the level of students' mathematics anxiety after using the PMBIT module decreased by an average of 11.55. While the level of students' mathematics anxiety after using the module in the low, medium, and high categories, respectively, was 40.5%, 56.8%, and 2.7%. Furthermore, there is an increase in student mathematics learning outcomes using the PMBIT Module with sig. 0.029 and a mean of 81.59
The Modern World Landscape of Data Science Online Education
Authors: Nikolskiy V. S. , Lukashenko M. A. , Sharova E. A.
Published: April 2022

Data science as an emerging branch of applied knowledge and a new field of study is showing a strong momentum. Besides, the corresponding sphere of educational research is actively developing. At the same time, most of the scientific publications are aimed at studying specific issues related to the content of the programs and their methodological support. The wider context and especially the international perspective are lacking for the necessary attention of researchers.In this regard, the purpose of our study was to summarize and systematize information about training programs in the field of data science presented on online platforms of the main macro-regions – America, Europe and Asia. For this purpose, we found out what elements the corpus of data science training programs consists of, as well as how courses are distributed on educational platforms by countries, organizational providers, level of education and duration of study. Based on the data obtained, we conducted a comparative interregional study of educational programs presented on online platforms.The findings made it possible to draw conclusions about the specifics of the global landscape of data science online education, as well as to determine the specifics of the Russian segment and to formulate recommendations for solving significant problems of the domestic economy using data science online education.
Analytical Review of Digital Accessibility Services on Official Sites of the World’s Best Universities
Authors: Kosova E. A.
Published: April 2022

The paper discusses the problem of e-learning accessibility for persons with disabilities. Development of e-learning content accessible to all students is gaining special relevance in the context of global trends in higher education related to the massive transition of learning to distance and hybrid formats. Based on the analysis of the official websites of 25 world’s top universities (according to the QS World University Rankings 2021), data on university digital accessibility services were systematized. The data search was carried out by total browsing of university sites’ structure and headings and by keywords. Data on 14 checklist categories were registered. Signs of administrative and project activities in the field of digital accessibility were found for 20 universities (80%), among which 10 (40%) have specialized structural subdivisions for digital accessibility. The content of digital accessibility web services contains data on the following topics: training in digital accessibility for educational content for authors and developers (14 university sites – 56%); a guide for authors (15–60%) and web developers (12–48%); consulting and assistance for authors and web developers (17–68%); accessibility examination (5–20%); legal norms (11–44%) and accessibility standards (16–64%); accessibility testing guide (16–64%); procurement requirements for accessible web products and services (8–32%); frequently asked questions (6–24%), etc. Based on the results of the analysis, the model of university digital accessibility services was developed and corresponding web site was published. It seems important to create similar web resources and corresponding structural subdivisions in universities of the Russian Federation, as well as to approve the intra-university local acts regulating the mandatory fulfillment of digital accessibility requirements in the development of educational content and the procurement of digital products and services. GOST R 52872-2019, based on WCAG 2.1, should be used as the basis for local legal regulations.
Avaliação do efeito da substituição de silagem de milho por ração extrusada de fibra de cana em ovinos
Authors:   Universidade Federal de Lavras, Siqueira Marco Túlio Santos , Oliveira Karla Alves ,   Universidade Estadual Paulista, Schultz Érica Beatriz ,   Universidade Federal de Viçosa, Sousa Luciano Fernandes ,   Universidade Federal do Tocantins, Silva Vitória Renata Souza ,   Universidade Federal de Uberlândia, Macedo Júnior Gilberto de Lima ,   Universidade Federal de Uberlândia
Published: April 2022

The objective was to evaluate food digestibility, dry matter intake, ingestive behavior and metabolic profile of ewes fed with extruded roughage instead silage. Twenty animals were used, with an average 54.5kg. The treatments consisted: 80%F:20%S; 60%F:40%S; 40%F:60%S; 20%F:80%S; and 100%S. Food, leavings, feces, urine, ingestive behavior and blood metabolites were evaluated. The variables DMI%BW and DMI(BW0.75) showed a negative linear response. There was positive linear response for RUM and CHEWING, negative linear response for IDLENESS, ERUM, EING and ECHEW and quadratic response for ING. Uric acid showed a statistical difference between treatments. It is concluded that the replacement corn silage by Foragge® extruded roughage can be done in up to 80%.
Globorotalia fohsi en la formación de Usme
Authors: Bürgl Hans
Published: April 2022

Una muestra procedente de 180 m de profundidad de la perforación No. 2 efectuada en el terreno de la fábrica de cerveza “Andina” en Bogotá, contuvo un foraminífero que consideramos como una nueva variedad de Globorotalia Fohsi y que describimos bajo el nombre de Globorotalia fohsi andina n. ssp. Esta forma está estrechamente relacionada con GJ. foshi foshi y con Gl. Praemenardii, las cuales caracterizan el Oligoceno Medio alto y el Oligoceno Superior bajo.
Según E. Hubach la muestra fosilífera pertenece a la parte superior de la formación de Usme, parte que no está preservada en la zona Típica, es decir, en el Valle del Tunjuelo al sur de Bogotá.
Se supone, por tanto, que la porción superior de la formación Usme pertenece a la parte superior del Oligoceno Medio o a la parte inferior del Oligoceno Superior.
Algunos moluscos del terciario medio de Colombia
Authors: Barrios M. Margoth
Published: April 2022

En este trabajo se describen los Lamelibranquios y Gasterópodos colectados por el doctor Hans Bürgl, Paleontólogo Jefe de la Sección de Paleontología, en los departamentos de Atlántico y Bolívar.
El material colectado en 37 estaciones diferentes, comprende 93 especies, de las cuales, 18 de Colombia, se citan por primera vez y 26 no existían en las colecciones del Museo Geológico. En su totalidad, este material se encuentra depositado en el Museo Geológico Nacional.
En cuanto se refiere a la edad de los fósiles, ésta se determina de una manera general y provisional, en espera dé un mejor conocimiento del Terciario de Colombia, lo cual esperamos conseguir próximamente con el estudio de la microfauna.
A excepción de una forma (Unio bitumen COOKE) que corresponde al Oligoceno Superior, las demás pertenecen al Mioceno marino.
Con el ánimo de facilitar el conocimiento de la paleontología en el país, se presentan todas las descripciones en español, habiendo seguido muy de cerca las descripciones originales o las de autores posteriores, las cuales aparecen en inglés, principalmente.
Al lector
Authors: Sarmiento Alarcón Alberto
Published: April 2022

En su propósito ele seguir divulgando los estudios realizados por el personal científico del Servicio Geológico Nacional, la Dirección de esta División ha resuelto reanudar la publicación de los trabajos más importantes que sobre la materia han sido seleccionados y los presenta al interés del lector, en la publicación que aspira a llenar una finalidad netamente científica.
La aplicación del sistema en el estudio de celda una de las piezas contenidas en este boletín corresponde al autor respectivo, tanto como la materia misma. El desarrollo de los trabajos se ha basado, desde luego, en la orientación que se viene dando en esta dependencia a toda su labor. No hay que esperar que dichos trabajos representen un tratado completo sobre la Geología de Colombia, pero sí una base para futuras investigaciones más amplias, detenidas y minuciosas.
En todo caso el Servicio Geológico Nacional cumple una función divulgadora para beneficio del país, como aporte modesto de sus recursos y posibilidades a la tarea científica del estudio de la geología universal.
Si logramos obtener, así sea en mínima parte los resultados que nos proponemos, ello sería suficiente como estímulo y satisfacción para nuestros propósitos.
Sedimentación cíclica en el geosinclinal cretáceo de la cordillera Oriental de Colombia
Authors: Bürgl Hans
Published: April 2022

Los estratos que constituyen la cordillera Oriental de Colombia comprenden desde el Precambriano hasta el Cuaternario. Entre ellos, los sedimentos del Cretáceo son los más frecuentes y de mayor grosor alcanzando su máximo espesor en los alrededores de Bogotá (Cuenca de Cundinamarca) con 16 000 metros. Hacia el Norte, su espesor se reduce a 2400 m y hacia la terminación sur de la cordillera alcanza sólo unos centenares de metros. En la Cuenca de Cundinamarca, el Cretáceo está compuesto predominantemente de lutitas oscuras, batiales, entre las cuales se interponen a distancias más o menos regulares, areniscas, calizas y otros depósitos litorales. La repartición de los fósiles, especialmente de las Amonitas, muestra que las intercalaciones litorales siempre forman las capas limítrofes entre pisos y subpisos. El hundimiento del geosinclinal cretáceo de la cordillera Oriental tuvo lugar por lo tanto de una manera cíclica: al principio de cada piso (o subpiso) se hundió rápidamente y se depositaron en él lutitas batiales. Después el hundimiento aminoró paulatinamente y los depósitos litorales avanzaron hacia el interior de la cuenca y en algunos casos la sedimentación cesó por completo. Con el nuevo hundimiento al principio del próximo piso, inmigraron al geosinclinal nuevas faunas pelágicas, en tanto que las faunas litorales se retiraron a las zonas costaneras y persistieron durante varios pisos. La composición litológica muy semejante y el grosor aproximado de los pisos indican que éstos se depositaron en períodos iguales de seis millones de años aproximadamente y los subpisos, en períodos de dos millones de años. Fuera de estos ciclos de los pisos, se reconocen ciclos mayores de 18 a 20 millones de años de duración. Estos fueron iniciados por movimientos tectónicos y extensas transgresiones subsiguientes. Dichos ciclos mayores empiezan con el Titoniano, Hauteriviano, Albiano y Senoniano. Los ciclos de los pisos empiezan simultáneamente en extensas regiones de la superficie terrestre, los ciclos mayores, en contraste, van sobre ella en forma de ondas. Se supone por lo tanto que los ciclos de los pisos tienen su origen en partes de la tierra más profundas que los ciclos mayores.
IMPLIKASI PERKEMBANGAN PERUMAHAN TERHADAP PENGGUNAAN LAHAN DI DESA BONGAN, KABUPATEN TABANAN, BALI.
Authors: Williyanto Benny , Sudharsana I Made Gde
Published: April 2022

The resulting growth and population density also affects the use of existing space. This is evidenced by the process of land conversion that is so rapid due to urban activity is extended to the edge of the city. Bongan Village is a part of Tabanan District which is located on the strategic urban outskirts, so it has a good appeal to be a residential area or commercial area. With its strategic location it will certainly affect the agricultural land in Bongan Village whose land use conditions are shifting. Therefore, The purpose of this study is to identify the development of agriculture land conversion into non-agricultural land and analyze the socio-economic conditions of the community related to the conversion of agricultural land there. This study uses spatial analysis to calculate the area of land change and describe the socio-economic condition. Based on the results of the identification and tracking of secondary data of agricultural land area recently decreased every year even almost more than 1 Ha of agriculture land converted into residential land, public infrastructure and road infrastructure development. In 2013 the planting area of Bongan Village is 464 Ha while in 2014, 2015 planting area in Bongan Village of 232 Ha so it can be seen the decrease of agricultural land area in Bongan Village.
PERUBAHAN PENGGUNAAN LAHAN AKIBAT PENETAPAN RENCANA TATA RUANG WILAYAH (RTRW) KABUPATEN JEMBRANA TAHUN 2012 di WILAYAH DESA PESISIR , KABUPATEN JEMBRANA-BALI.
Authors: Wijaya I Made Anggra , Sukamara I Nyoman , Kurniawan Wayan Damar Windu
Published: April 2022

The coastal area in Jembrana Regency is part of the South Bali sea which stretches in the southern part of the Jembrana Regency region. The Regional Spatial Planning Document (RTRW) is prepared to be used as a guideline for land allotment in an area. This study aims to examine changes in land use in coastal villages in 2009 and 2017, analyzing land suitability between changes in land use that occur with the 2012 RTRW of Jembrana Regency. The results showed changes in paddy fields to residential land use and other buildings had an area of about 236.48 ha. Changes in dry land use to residential land use and other buildings have an area of 794.16 ha. The villages that experience land use changes include Melaya, Candikusuma, Tuwed, Banyubiru, Baluk, Penyaringan, Delod Berawah, and Perancak. based on the results of digitization and the results of observations of researchers the suitability of land use changes that occur mostly to building tourism accommodation and fisheries activities. Land use changes that occur in the cupel village, pengambengan, tegal badeng barat, tegal badeng timur, and lelateng that occur mostly become supporting buildings for fisheries activities.
PREFERENSI MASYARAKAT DALAM PEMANFAATAN BUS TRANS SARBAGITA SEBAGAI MODA ANGKUTAN UMUM DI KAWASAN SARBAGITA
Authors: Jayanthy Ida Ayu Gede Krisna , Parsa Ida Bagus Made
Published: April 2022

Trans Sarbagita is a road-based mass public transportation system on a fixed and regular route network in the Sarbagita area. This study aims to determine the characteristics of the Trans Sarbagita bus mode in passenger service and the factors that influence people's preferences in using the Trans Sarbagita bus as a mode of public transportation in the Sarbagita area. Data collection was carried out through interviews and distributing questionnaires. This type of research uses a quantitative approach. The number of samples used was 65 respondents using the accidental sampling method. Data analysis techniques used factor analysis. The result of this research is that trans sarbagita is a public transport/bus rapid transit (BRT) that serves passengers according to the minimum service standard which was initiated to reduce the level of traffic congestion in the Sarbagita area. The percentage that affects people's preferences in using the Trans Sarbagita bus as a mode of public transportation in the Sarbagita area is 94.570% which can be explained by these four factors. Each factor is named as follows: factor 1 is called proximity bus stop factor to public facilities, factor 2 is called security, factor 3 is called a tariff, factor 4 is called operational schedule.