bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of the Utility of RP-TLC Technique and Different Computational Methods to Assess the Lipophilicity of Selected Antiparasitic, Antihypertensive, and Anti-inflammatory Drugs
Authors: Pyka-Pająk Alina , Parys Wioletta , Dołowy Małgorzata
Published: September 2019

The aim of this study was to assess the lipophilicity of selected antiparasitic, antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) by means of reversed phase–thin layer chromatography (RP-TLC) as well by using Soczewiński–Wachtmeister’s and J. Ościk’s equations. The lipophilicity parameters of all examined compounds obtained under various chromatographic systems (i.e., methanol-water and acetone-water, respectively) and those determined on the basis of Soczewiński-Wachtmeister’s and Ościk’s equations (i.e., RMWS and RMWO) were compared with the theoretical ones (e.g., AlogPs, AClogP, milogP, AlogP, MlogP, XlogP2, XlogP3) and the experimental value of the partition coefficient (logPexp). It was found that the RMWS parameter may be a good alternative tool in describing the lipophilic nature of biologically active compounds with a high and low lipophilicity (i.e., antihypertensive and antiparasitic drugs). Meanwhile, the RMWO was more suitable for compounds with a medium lipophilicity (i.e., non-steroidal anti-inflammatory drugs). The chromatographic parameter φ0(a) can be helpful for the prediction of partition coefficients, i.e., AClogP, XlogP3, as well as logPexp of examined compounds.
An Orally Administrated Hyaluronan Functionalized Polymeric Hybrid Nanoparticle System for Colon-Specific Drug Delivery
Authors: Kotla Niranjan G. , Burke Orla , Pandit Abhay , Rochev Yury
Published: September 2019

There is a pressing clinical need for advanced colon-specific local drug delivery systems that can provide major advantages in treating diseases associated with the colon, such as inflammatory bowel disease (IBD) and colon cancer. A precise colon targeted drug delivery platform is expected to reduce drug side effects and increase the therapeutic response at the intended disease site locally. In this study, we report the fabrication of hyaluronan (HA) functionalized polymeric hybrid nanoparticulate system (Cur-HA NPs) by using curcumin as a model fluorescent drug. The Cur-HA NPs were about 200–300 nm in size, −51.3 mV overall surface charge after HA functionalization, with 56.0% drug released after 72 h in simulated gastrointestinal fluids. The Cur-HA NPs did not exhibit any cytotoxicity by AlamarBlue, PicoGreen and Live/Dead assays. Following the Cur-HA NPs use on HT-29 monolayer cell cultures demonstrating, the efficacy of HA functionalization increases cellular interaction, uptake when compared to uncoated nanoparticulate system. These findings indicate that HA functionalized nano-hybrid particles are effective in delivering drugs orally to the lower gastrointestinal tract (GIT) in order to treat local colonic diseases.
Soybean Interaction with Engineered Nanomaterials: A Literature Review of Recent Data
Authors: Coman Vasile , Oprea Ioana , Leopold Loredana Florina , Vodnar Dan Cristian , Coman Cristina
Published: September 2019

With a continuous increase in the production and use in everyday life applications of engineered nanomaterials, concerns have appeared in the past decades related to their possible environmental toxicity and impact on edible plants (and therefore, upon human health). Soybean is one of the most commercially-important crop plants, and a perfect model for nanomaterials accumulation studies, due to its high biomass production and ease of cultivation. In this review, we aim to summarize the most recent research data concerning the impact of engineered nanomaterials on the soya bean, covering both inorganic (metal and metal-oxide nanoparticles) and organic (carbon-based) nanomaterials. The interactions between soybean plants and engineered nanomaterials are discussed in terms of positive and negative impacts on growth and production, metabolism and influences on the root-associated microbiota. Current data clearly suggests that under specific conditions, nanomaterials can negatively influence the development and metabolism of soybean plants. Moreover, in some cases, a possible risk of trophic transfer and transgenerational impact of engineered nanomaterials are suggested. Therefore, comprehensive risk-assessment studies should be carried out prior to any mass productions of potentially hazardous materials.
Evaluation of the Influence of Raw Almonds on Appetite Control: Satiation, Satiety, Hedonics and Consumer Perceptions
Authors: Hollingworth Sophie , Dalton Michelle , Blundell John E. , Finlayson Graham
Published: August 2019

Snack foods can be substantial contributors to daily energy intake, with different types of snacks exerting potentially different effects on satiety per calorie consumed. The present research compared the effect of consuming almonds as a mid-morning snack compared to an energy and weight-matched comparator snack (savoury crackers) or the equivalent weight of water (zero energy control). In a crossover design, 42 female participants (age: 26.0 ± 7.9, BMI: 22.0 ± 2.0) consumed a fixed breakfast then a mid-morning snack. Appetite, 24-h energy intake, food hedonics, and consumer perceptions of the snack foods were assessed under laboratory conditions. AUC analyses revealed a lower overall hunger drive after consuming almonds compared to crackers or water. There was no difference in 24-h energy intake in the almond compared to the cracker or the zero-energy control condition, however participants consumed more energy in the cracker condition compared to the zero-energy control condition. In addition, almonds suppressed hedonic preference (implicit wanting) for consuming high-fat foods and demonstrated a higher satiety quotient (SQ) than crackers. Almonds were perceived to have a more favourable consumer profile aligned with successful weight management. In conclusion, these findings demonstrate that in the context of a 24-h period of objectively measured energy intake, raw almonds are effective for controlling appetite compared to an energy matched alternative snack. This trial was registered at clinicaltrials.gov [NCT02480582].
Improved Eating Behaviour and Nutrient Intake in Noncompliant Patients with Phenylketonuria after Reintroducing a Protein Substitute: Observations from a Multicentre Study
Authors: Green Benjamin , Rahman Yusof , Firman Sarah , Adam Sarah , Jenkinson Fiona , Nicol Claire , Adams Sandra , Dawson Charlotte , Robertson Louise , Dunlop Carolyn , Cozens Alison , Hubbard Gary , Stratton Rebecca
Published: August 2019

Noncompliance is widespread in adults with PKU and is associated with adverse metabolic, nutritional and cognitive abnormalities. Returning to the PKU diet is important for this at-risk population, yet for many this is challenging to achieve. Strategies that ease the return to the PKU diet, while offering nutritional and cognitive advantages, are needed. Twelve PKU adults (33.7 ± 2.6 years), who had been noncompliant for 4.5 years (range: 1 to 11 years), took 33 g of a low-volume, nutrient-enriched, protein substitute daily for 28 days. Outcomes of eating behaviour, nutrient intake and mood were assessed at entry (baseline, days 1–3) and after the intervention period (days 29–31). At baseline, intakes of natural protein and estimated phenylalanine were high (66.4 g and 3318.5 mg, respectively) and intakes of calcium, magnesium, iron, zinc, iodine and vitamin D were below country-specific recommendations. With use of the experimental protein substitute, natural protein and estimated phenylalanine intake declined (p = 0.043 for both). Fat and saturated fat intakes also decreased (p = 0.019 and p = 0.041, respectively), while energy and carbohydrate intake remained unchanged. Micronutrient intake increased (p ≤ 0.05 for all aforementioned) to levels well within reference nutrient intake recommendations. Blood vitamin B12 and vitamin D increased by 19.8% and 10.4%, respectively. Reductions in anxiety and confusion were also observed during the course of the study yet should be handled as preliminary data. This study demonstrates that reintroducing a low-volume, nutrient-enriched protein substitute delivers favourable nutritional and possible mood benefits in noncompliant PKU patients, yet longer-term studies are needed to further confirm this. This preliminary knowledge should be used in the design of new strategies to better facilitate patients’ return to the PKU diet, with the approach described here as a foundation.
Decrease in Bat Diversity Points towards a Potential Threshold Density for Black Cherry Management: A Case Study from Germany
Authors: Geschke Jonas
Published: September 2019

In times of land use changes towards more close-to-nature forestry, the application of bioindicators becomes an interesting tool for effective land-use management schemes. Forest managers are increasingly confronted by alien tree species. Therefore, this case study aimed to investigate the influence of the invasive black cherry (Prunus serotina) on bats (Chiroptera: Verpertilionidae) in pine (Pinus sylvestris) forest ecosystems, in order to identify the potential of bats as bioindicators for a black cherry invasion. In three pre-classified succession stages of the black cherry, the diversity and relative abundance of bats were bioacoustically monitored for a period of 60 nights. From the bat call recordings made during the study period, eight bat species could be identified to species level. Within the succession stages of pine monoculture and light black cherry forest, a comparable bat diversity of eight bat species and three sonotypes with a similar relative abundance were observed. In dense black cherry forest, only four species and one sonotype were detected. Compared to the pine monoculture and light black cherry forest, the overall abundance of the bat community was significantly lower in the dense black cherry forest. Upon evaluation, those bat species associated with the edge and narrow space forager guilds were found to have a high sensitivity to a dense black cherry understory within naturally monocultural pine stands. Their activity patterns indicate that the transition from light to dense black cherry understory can be considered as a potential threshold value for a close-to-nature black cherry understory density in high canopy pine forest stands.
Correction: Sophia, B.; et al. Presenting Precision Glycomacromolecules on Gold Nanoparticles for Increased Lectin Binding. Polymers 2017, 9, 716
Authors: Boden Sophia , Wagner Kristina G. , Karg Matthias , Hartmann Laura
Published: August 2019

In the original version of this Article [...]
Comparison of Growth Characteristics and Properties of CVD TiN and TiO2 Anti-Coking Coatings
Authors: Tang Shiyun , Liu Tao , Duan Shuiping , Guo Junjiang , Tang Anjiang
Published: August 2019

Coating metals with anti-coking materials inhibit their catalytic coking and are especially beneficial in the pyrolysis of hydrocarbon fuels. It is believed that growth characteristics and properties may play a pivotal role in the anti-coking performance of chemical vapor deposition (CVD) coatings. In this study, TiN and TiO2 coatings were obtained by CVD using TiCl4–N2–H2 and TiCl4–H2–CO2 systems, respectively. The effects of deposition time, residence time, and partial pressure were examined, and the coating microstructure was characterized by scanning electron microscopy (SEM). The results reveal that the effect of deposition parameters on the growth characteristics of TiN and TiO2 coatings is very different. The growth of the TiN coating shows characteristics of the island growth model, while the TiO2 coating follows the layer model. In general, the growth rate of the star-shaped TiN crystals is higher than that of crystals of other shapes. For the TiO2 coating, the layer mode growth characteristics indicate that the morphology of the TiO2 coating does not change significantly with the experimental conditions. Coking tests showed that the morphology of non-catalytic cokes is not only affected by the temperature, pressure, and coking precursor, but is also closely related to the surface state of the coatings. Both TiN and TiO2 coatings can effectively prevent catalytic coking and eliminate filamentous cokes. In some cases, however, the N or O atoms in the TiN and TiO2 coatings may affect common carbon deposits formed by non-catalytic coking, such as formation of needle-like and flaky carbon deposits.
Characterization of Natural Composites Fabricated from Abutilon-Fiber-Reinforced Poly (Lactic Acid)
Authors: Wang Hua , Hassan Elwathig. A. M. , Memon Hafeezullah , Elagib Tienah. H. H. , Abad AllaIdris Fadlelmoula
Published: September 2019

In recent decades, natural-fiber-reinforced poly (lactic acid) (PLA) composites have received a great deal of attention. In this study, biocomposites of poly (lactic acid) and abutilon fibers are prepared by using melt blending and an extruder. The effects of fiber additions on rheological, thermomechanical, thermal, and morphological properties are investigated using a rheometer, dynamic mechanical analysis (DMA), differential scanning calorimeter (DSC), TGA, and SEM, respectively. The DSC results indicate that the fibers acted as a nucleating agent, which led to enhancing the crystallization of PLA. The results also reveal that the thermal stability of PLA was improved by abutilon fibers. Moreover, higher values of storage modulus are observed, which are attributed to strong interfacial adhesion. In addition, thetan delta isreduced upon the addition of fiber content into the PLA matrix, which restricts the mobility of PLA polymer molecules in the presence of the fibers. The improvement of the properties and energy absorption capabilities of such biocomposites signifies the great potential of abutilon fibers as reinforcement in green composites.
The Link between Economic Complexity and Carbon Emissions in the European Union Countries: A Model Based on the Environmental Kuznets Curve (EKC) Approach
Authors: Neagu Olimpia
Published: August 2019

The aim of the paper is to apply the Environmental Kuznets Curve (EKC) model in order to explore the link between economic complexity index (ECI) and carbon emissions, in 25 selected European Union (EU) countries from 1995–2017. The study examines a cointegrating polynomial regression (CPR) for a panel data framework as well as for simple time series of individual countries. In the model is also included the variable ‘energy intensity’ as main determinant of carbon emissions. Depending on economic complexity, the CO2 emissions pattern was found to exhibit an inverted U-shaped curve: in the initial phase, pollution increases when countries augment the complexity of the products they export using and after a turning point the rise of economic complexity suppress the pollutant emissions. The panel cointegration test indicates a long-run relationship between economic complexity, energy intensity and carbon emissions. It was also found that a rise of 10% of energy intensity would lead to a 3.9% increase in CO2 emissions. The quadratic model incorporating ECI is validated for the whole panel as well as for six countries (Belgium, France, Italy, Finland, Sweden and the United Kingdom). The graphical representation of the EKC in these countries is discussed. Policy implications are also included.
Real-Time Assessment of E-Cigarettes and Conventional Cigarettes Emissions: Aerosol Size Distributions, Mass and Number Concentrations
Authors: Lampos Spyros , Kostenidou Evangelia , Farsalinos Konstantinos , Zagoriti Zoi , Ntoukas Aristeidis , Dalamarinis Konstantinos , Savranakis Panagiotis , Lagoumintzis George , Poulas Konstantinos
Published: August 2019

Cigarette smoke is a complex mixture of chemical compounds which are emitted during the processes of tobacco combustion. Electronic cigarettes (e-cigs) are expected to produce less harmful compounds due to the absence of tobacco leaf combustion. However, potential risks of the passive exposure to the aerosol exhaled by e-cig users have been raised in the last decade. In this study, the aerosols with diameter less than 1 μm (PM1) produced by vaping of various e-cig liquids were compared to those generated by smoking conventional cigarettes in real time. The mass and number concentration along with the number size distribution were measured in a closed room of 35 m3 volume. Our results showed that aerosols emitted from e-cig liquids had a different profile compared to those from conventional cigarettes. Although e-cigs initially produced higher particle mass and number concentrations, their emissions had much shorter lifetime of approximately 10–20 s, in comparison with the conventional and hand-rolling cigarette particulate emissions which had a dissipation time of approximately 1.4 h in a 35 m3 room. E-cigs emitted aerosols which volatilized rapidly, as they probably consisted almost only of propylene glycol and/or vegetable glycerin.
MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors
Authors: Aralaguppe Shambhu G. , Ambikan Anoop T. , Ashokkumar Manickam , Kumar Milner M. , Hanna Luke Elizabeth , Amogne Wondwossen , Sönnerborg Anders , Neogi Ujjwal
Published: August 2019

The detection of drug resistance mutations (DRMs) in minor viral populations is of potential clinical importance. However, sophisticated computational infrastructure and competence for analysis of high-throughput sequencing (HTS) data lack at most diagnostic laboratories. Thus, we have proposed a new pipeline, MiDRMpol, to quantify DRM from the HIV-1 pol region. The gag-vpu region of 87 plasma samples from HIV-infected individuals from three cohorts was amplified and sequenced by Illumina HiSeq2500. The sequence reads were adapter-trimmed, followed by analysis using in-house scripts. Samples from Swedish and Ethiopian cohorts were also sequenced by Sanger sequencing. The pipeline was validated against the online tool PASeq (Polymorphism Analysis by Sequencing). Based on an error rate of <1%, a value of >1% was set as reliable to consider a minor variant. Both pipelines detected the mutations in the dominant viral populations, while discrepancies were observed in minor viral populations. In five HIV-1 subtype C samples, minor mutations were detected at the <5% level by MiDRMpol but not by PASeq. MiDRMpol is a computationally as well as labor efficient bioinformatics pipeline for the detection of DRM from HTS data. It identifies minor viral populations (<20%) of DRMs. Our method can be incorporated into large-scale surveillance of HIV-1 DRM.
Spatial Frequency Tuning and Transfer of Perceptual Learning for Motion Coherence Reflects the Tuning Properties of Global Motion Processing
Authors: Asher Jordi M. , Romei Vincenzo , Hibbard Paul B.
Published: September 2019

Perceptual learning is typically highly specific to the stimuli and task used during training. However, recently, it has been shown that training on global motion can transfer to untrained tasks, reflecting the generalising properties of mechanisms at this level of processing. We investigated (i) if feedback was required for learning in a motion coherence task, (ii) the transfer across the spatial frequency of training on a global motion coherence task and (iii) the transfer of this training to a measure of contrast sensitivity. For our first experiment, two groups, with and without feedback, trained for ten days on a broadband motion coherence task. Results indicated that feedback was a requirement for robust learning. For the second experiment, training consisted of five days of direction discrimination using one of three motion coherence stimuli (where individual elements were comprised of either broadband Gaussian blobs or low- or high-frequency random-dot Gabor patches), with trial-by-trial auditory feedback. A pre- and post-training assessment was conducted for each of the three types of global motion coherence conditions and high and low spatial frequency contrast sensitivity (both without feedback). Our training paradigm was successful at eliciting improvement in the trained tasks over the five days. Post-training assessments found evidence of transfer for the motion coherence task exclusively for the group trained on low spatial frequency elements. For the contrast sensitivity tasks, improved performance was observed for low- and high-frequency stimuli, following motion coherence training with broadband stimuli, and for low-frequency stimuli, following low-frequency training. Our findings are consistent with perceptual learning, which depends on the global stage of motion processing in higher cortical areas, which is broadly tuned for spatial frequency, with a preference for low frequencies.
Estimation of Soil Erosion in the Chaohu Lake Basin through Modified Soil Erodibility Combined with Gravel Content in the RUSLE Model
Authors: Hu Sai , Li Long , Chen Longqian , Cheng Liang , Yuan Lina , Huang Xiaodong , Zhang Ting
Published: August 2019

It is generally acknowledged that soil erosion has become one of the greatest global threats to the human–environment system. Although the Revised Universal Soil Loss Equation (RUSLE) has been widely used for soil erosion estimation, the algorithm for calculating soil erodibility factor (K) in this equation remains limited, particularly in the context of China, which features highly diverse soil types. In order to address the problem, a modified algorithm describing the piecewise function of gravel content and relative soil erosion was used for the first time to modify the soil erodibility factor, because it has been proven that gravel content has an important effect on soil erosion. The Chaohu Lake Basin (CLB) in East China was used as an example to assess whether our proposal can improve the accuracy of soil erodibility calculation and soil erosion estimation compared with measured data. Results show that (1) taking gravel content into account helps to improve the calculation of soil erodibility and soil erosion estimation due to its protection to topsoil; (2) the overall soil erosion in the CLB was low (1.78 Mg·ha−1·year−1) the majority of which was slight erosion (accounting for 85.6%) and no extremely severe erosion; and (3) inappropriate land use such as steep slope reclamation and excessive vegetation destruction are the main reasons for soil erosion of the CLB. Our study will contribute to decision-makers to develop soil and water conservation policies.
Phosphorus Removal with Coagulation Processes in Five Low Buffered Lakes—A Case Study of Mesocosm Research
Authors: Łopata Michał , Augustyniak Renata , Grochowska Jolanta , Parszuto Katarzyna , Tandyrak Renata
Published: August 2019

This research deals with the impact of aluminum coagulants, used as a tool for the rehabilitation of water bodies, on changes in the phosphorus content in lakes with low alkalinity of water. Mesocosm scale experimental investigations in situ using polyaluminium chloride were carried out, based on five lakes with different levels of water buffering capacity (<1.0–2.5 meq L−1). The research was accomplished using three coagulant doses (half a dose, a whole dose, and a double dose calculated for phosphorus inactivation in a lake ecosystem). The results were compared with the ones from the control mesocosms. The study was carried out in two consecutive years. It was shown that the effectiveness of phosphorus removal from a water column was related to the dose of the coagulant, pH value, and the content of organic compounds. The lowest treatment effectiveness was found for lakes, with the most severe symptoms for dystrophy, which were abundant with humic compounds. As the water alkalinity increased, so did the ability of the coagulant to adsorb phosphorus, while the ecosystem’s load of aluminum in toxic forms decreased. Doubling the standard dose did not result in a noticeable improvement in the water quality. The results allow us to evaluate the chances of successful lake restoration by applying aluminum coagulants to natural water bodies which are susceptible to acidification.
PENGARUH DEWAN KOMISARIS DAN KOMITE AUDIT TERHADAP PENGUNGKAPAN CORPORATE SOCIAL RESPONSIBILITY (STUDI EMPIRIS PERUSAHAAN HIGH PROFILE DI BURSA EFEK INDONESIA)
Authors: Rivandi Muhammad , Putri Andi Harita
Published: September 2019

ABSTRACT
 
This study aims to examine the effect of the Board of Commissioners and the Audit Committee on the Disclosure of Corporate Social Responsibility (Empirical Study on High Profile Companies on the Indonesia Stock Exchange 2013-2017). The method of data collection is done by documentation of data sourced from annual reports published through the Indonesia Stock Exchange. The sample in this study were 42 companies listed on the Indonesia Stock Exchange which were selected using purposive sampling. The analytical method used was a panel regression model. Data is tested using Eviews software version 8.0. Based on the hypothesis the test results show that the board of commissioners has no effect on disclosure of corporate social responsibility while the audit committee has a positive and significant effect on corporate social responsibility.
 
Keywords: Board of Commissioners, Audit Committee, Corporate Social Responsibility of dicclosure
REPRESENTATIVIDADE POLÍTICA NO BRASIL: REFLEXÕES SOBRE A COTA DE GÊNERO
Authors: Silveira Camila Souza , Garcia Edmar Augusto Semeão , Bacos Raissa Maia
Published: September 2019

RESUMO: O presente trabalho conta com o levantamento histórico a respeito da política no Brasil e suas mudanças, dando ênfase as lutas pela conquista do voto e lutas atuais que buscam aumentar a representatividade política das mulheres brasileiras. A revisão bibliográfica nos traz algumas informações sobre as vertentes de movimentos, apontando as diferenças entre os movimentos de mulheres e os movimentos feministas.Em seguida, são trabalhadas as conquistas desses movimentos marginalizados durante anos, como por exemplo, a política de cotas para mulheres na política, que corresponde a 30% do total de candidatos em cada partido. São ainda apresentados problemas que tornam a presença da mulher na política um evento quase extinto, mesmo com a existência de políticas afirmativas de incentivo a essa prática.Ao longo do trabalho, percebe- se que o fato de a mulher não participar efetivamente da política não é apenas uma questão eleitoral, visto que quem preencheu o cargo de presidente do Brasil de 2010 até 2014 e foi reeleita, foi uma mulher, mas também uma questão que passa pelo nosso sistema político atual.PALAVRAS-CHAVE: Representatividade, política, mulheres, cotas.
A GEOGRAFIA DOS VOTOS E A CONSTRUÇÃO DISCURSIVA DOS MANDATOS DE DEPUTADOS FEDERAIS DA ZONA DA MATA MINEIRA: UMA ANÁLISE DAS ÊNFASES DE MANDATO A PARTIR DE VARIÁVEIS POLÍTICAS E COMUNICATIVAS
Authors: Mira Gustavo Fernandes Paravizo , Leal Paulo Roberto Figueira , Oliveira Luiz Ademir de , Almeida Paula Emília Gomes de
Published: September 2019

Este paper apresenta alguns resultados das análises eleitorais de 2014 e do conteúdo produzido em 2015 e 2016 a partir da trajetória política, do desempenho eleitoral e das postagens publicadas nas redes sociais pelos deputados federais com domicílio na cidade mineira de Juiz de Fora, na mesorregião da Zona da Mata, entre eles, Marcus Pestana, Júlio Delgado e Margarida Salomão. A partir da discussão epistêmica dos campos da comunicação e da política, desenvolve-se um aparato teórico-metodológico capaz verificar as especificidades dos mandatos. Neste sentido, confirmou-se a existência de diferentes padrões de acordo com as evidências geradas a partir da conjugação das variáveis supracitadas.
Educação e Gênero: um entrelaçamento necessário para a educação constitucional democrática
Authors: Brugger Andrey da Silva , Machado José Antônio Gomes , Lopes Monique Rodrigues
Published: September 2019

O presente trabalho busca problematizar a educação constitucional democrática baseada em direitos humanos, apresentando como temática a relação entre educação e gênero frente aos recentes projetos que atentam contra o design formatado pela Constituição Federal de 1988. Através da discussão de bibliografia da ciência politica, pedagogia e direito, tentamos emoldurar fundamentos para negar esses projetos, levantar dados que não podem ser silenciados e defender uma educação mais inclusiva, cidadã, democrática, que desenvolva livremente a pessoa, prepare para o exercício da cidadania e qualifique para o mercado de trabalho.
Mulheres e crianças nas salas de cinema no início do século XX: uma análise sobre os públicos nos espaços de projeção em Portugal
Authors: Moraes Juliana de Mello
Published: August 2019

O convívio e as interações entre os frequentadores das salas de cinema, no início do século XX, suscitaram múltiplos discursos expressos nos periódicos da época. A partir dessa documentação avalia-se as práticas culturais, as sociabilidades e, ainda, alguns significados atribuídos as salas de cinema pelos contemporâneos, em especial entre os moradores das menores cidades. Embora subsista a impossibilidade de captar todas as discussões ou controvérsias geradas pelo espectáculo cinematográfico em Portugal durante as suas primeiras décadas e, principalmente, os seus efeitos sobre os públicos, é possível perscrutar, no entanto, os seus sentidos mais evidentes. É importante sublinhar que esses discursos focavam sobretudo os efeitos do cinema e seus espaços de exibição sobre as mulheres e as crianças, indicando, paralelamente, o papel desempenhado por esses grupos na conformação da nova mídia.
El Acceso al Turismo en Argentina en la Última Década: entre la democratización y la inequidad
Authors: Schenkel Erica , Ercolani Patricia
Published: September 2019

El turismo, entendido como práctica social, se enmarca en el campo de análisis de las Ciencias Sociales. En este contexto, la investigación analiza la participación turística de los argentinos, desde una perspectiva socio-económica. Particularmente aborda el periodo de expansión del turismo nacional que se origina luego de la crisis del año 2001. Los resultados comprueban que a pesar del crecimiento alcanzado, las prácticas turísticas en Argentina continúan siendo de acceso minoritario. El disfrute del turismo es parte de las inequidades que acumulan las personas ubicadas en las posiciones sociales más postergadas. A medida que se precariza el nivel de ingresos, la condición de ocupación y el nivel educativo del grupo familiar, disminuye la posibilidad de vacacionar.
Sistem Pakar Diagnosa Penyakit THT
Authors: Lisnawita Lisnawita , Van FC Lucky Lhaura , Lianda Evi
Published: August 2019

Intisari - Dalam mendiagnosa penyakit THT(Telinga, Hidung, tenggorokan), seorang dokter memerlukan data berupa gejala-gejala yang sedang dialami oleh si penderita. Gejala-gejala ini dapat di peroleh   dari   pemeriksaan   fisik   atau   laboratorium.   Sebagai   seorang   manusia   yang   memiliki keterbatasan, begitu juga dengan dokter THT tentunya memiliki kelemahan. Apabila terdapat penyakit THT baru atau lupa tentang jenis penyakit dan pengobatan nya, maka seorang ahli THT mencari kembali buku-buku atau dokumen-dokumen yang membahas tentang penyakit THT tersebut. Cara ini tentu saja akan memakan waktu yang lama. Penelitian ini bertujuan untuk merancang sistem pakar untuk mendiagnosa penyakit THT. Perancangan ini di mulai dari pembuatan basis pengetahuan dilanjutkan  dengan  identifikasi  rule  dan    perancangan  input-output  dengan    metode  fordward chaining . Hasil rancangan pada penelitian ini diharapkan mampu membantu pekerjaan dokter menjadi lebih mudah sehingga memberikan hasil diagnosa penyakit THT menggunakan sistem pakar. Kata kuci: Sistem pakar, penyakit THT, Forward Chaining
Sistem Klasifikasi Kinerja Satpam Menggunakan Metode Naїve Bayes Classifier
Authors: Wibowo Adityo Permana , Hartati Sri
Published: August 2019

Intisari - PT. Garuda Merah Indoensia merupakan perusahaan BUJP yang menangani pendidikan dan pelatihan Satpam (Satuan Pengamanan). Saat ini di perusahaan tersebut dalam menilai kinerja satpam menggunakan sistem “teman menilai teman” yang bisa menimbulkan hasil kinerja yang tidak akurat. Satpam merupakan bentuk pengamanan swakarsa yang bertugas membantu Polri dibidang penyelenggaraan keamanan dan ketertiban masyarakat, terbatas pada lingkungan kerjanya. Penelitian ini bertujuan untuk menghasilkan sebuah sistem yang mampu melakukan klasifikasi kinerja baik, cukup, dan buruk yang dilihat dari kemampuan, kepribadian dan ketrampilan masing-masing satpam dengan menggunakan metode Naïve Bayes Classifier. Metodologi penelitian ini dimulai dengan mengajukan pertanyaan berupa kuesioner kepada satpam yang bekerja pada sebuah instansi, kemudian dilakukan wawancara dengan direktur Pusdiklat satpam. Data tersebut akan digunakan sebagai data sampel.   Proses   penerapan   metode   Naive   Bayes   Classifier   untuk   klasifikasi   kinerja   satpam menggunakan perhitungan numerik tiga variabel. Pengujian klasifikasi menggunakan 39 data uji dan menghasilkan prosentase nilai kebenaran sebesar 92,31%, prosentase kinerja baik 20,51%, kinerja cukup 71,79%, kinerja buruk 7,69%. Dengan demikian aplikasi ini bisa digunakan untuk membantu mengetahui kinerja satpam. Kata Kunci - Klasifikasi, Kinerja Satpam, Naïve Bayes Classifier
Implementasi Metode Rough Set Untuk Menentukan Kelayakan Bantuan Dana Hibah Fasilitas Rumah Ibadah
Authors: Jamaris Muhamad
Published: August 2019

Intisari - Bantuan Hibah merupakan salah satu program pemerintah menteri dalam negeri RepublikIndonesia yang diatur dalam peraturan menteri dalam negeri atau undang-undangkah nomor 14  tahun2016, untuk mendukung proses pemberian dana hibah bantuan fasilitas rumah ibadah. Azaz yang digunakan dalam menentukan keputusan harus bersifat keadilan, kepatutan dan rasionalitas.  Data mining telah berkembang pesat dan menambah nilai suatu informasi yang tersimpan dalam database. Salah satu algoritma data mining yang cukup sederhana adalah Rough Set. Dengan penggunaan metode Rough Set dapat membentuk pola aturan atau rule yang bisa dijadikan pedoman dalam menentukan pemohon yang layak diberikan bantuan. Aspek atau atribut yang dinilai dengan menggunakan metode rough set terdiri-dari: kelengkapan persyaratan, status bantuan, tahun pendirian, kondisi dan tingkat rutinitas rumah ibadah. Penelitian mengenai kelayakan bantuan hibah fasilitas rumah ibadah dibiro kesra provinsi Riau. Menggunakan metode rough set dapat digunakan untuk menghasilkan keluaran berupa  rule atau pola aturan  dengan  berbagai  kondisi  yang  menghasilkan  keputusan  diterima, diproses dan ditolak. Dari pola atau rule tersebut bisa disimpulkan pemohon bantuan yang layak diberikan bantuan atau tidak. Tujuan dari penerapan metode rough set ini adalah untuk membantu pihak pegawai biro kesra provinsi Riau di dalam mengetahui pemohon yang layak diberikan bantuan atau tidak layak diberikan bantuan dana hibah fasilitas rumah ibadah di pemerintahan provinsi Riau. Manfaat yang diperoleh adalah dapat ditentukan secara dini kemungkinan calon penerima bantuan hibah fasilitas rumah ibadah berdasarkan knowledge yang diperoleh melalui metode rough set. Kata kunci : Data Mining, Rough Set, Bantuan Hibah. Rumah Ibadah
Estudio de un conversor óptico fotorrefractivo y sus aplicaciones
Authors:   , Tebaldi Myrian Cristina
Published: September 2019

Objetivos de la tesis: - estudiar el registro y reconstrucción de distribuciones unidimensionales (redes de Ronchi) de baja frecuencia, registradas incoherentemente en un conversor óptico fotorrefractivo, sin soporte holográfico y en configuración transversal. En particular, se pretende caracterizar el estado de polarización del haz de lectura producido por la modulación de birrefríngencia inducida en el medio. El interés, en este estudio, es controlar el contraste y así optimizar la imagen reconstruida a la salida del sistema. - implementar los efectos Talbot y Lau a partir de una red registrada en un cristal fotorrefractivo. Esto ha permitido visualizar estos efectos con características novedosas, propias de la naturaleza del registro y en esta modalidad efectuar un tratamiento unificado de los fenómenos analizados. A su vez, estas características han motivado la implementación fotorrefractiva de los interferómetros Talbot y Lau.
Obtención y valoración de carotenoides florales de plantas que crecen en la provincia de Buenos Aires
Authors:   , Natalucci Claudia Luisa
Published: September 2019

Se ha estudiado el contenido en carotenoides totales, carotenos y pigmentos monohidroxilados y dihidroxilados de un grupo de especies que crecen en estado silvestre o que se cultivan en la provincia de Buenos Aires. Independientemente del efectivo aporte al conocimiento fitoquímico de nuestra Flora, los objetivos del trabajo han estado dirigidos a la búsqueda de especies con un contenido destacado en carotenoides hidroxilados, que son los que poseen mayor poder pigmentante al ser incorporados a la dieta de aves de corral.
Productividad en pastizales serranos a lo largo del gradiente altitudinal
Authors:   , Pérez Carolina Alejandra
Published: September 2019

El presente es un estudio de la estructura y función de pastizales serranos de las cuencas altas de las Sierras Australes, los cuales adquieren importancia en el control de la erosión y en el mantenimiento de calidad del agua de los arroyos. Tiene como fin estimar la biomasa y la productividad primaria neta, aérea y subterránea de pastizales de la cuenca alta del Arroyo Sauce Grande y establecer si existen diferencias de comportamiento de esas variables a lo largo de un gradiente complejo: la altitud. En segundo lugar se intenta caracterizar a los ciclos biogeoquímicos del C, N, P, K y Ca en pastizales naturales, a lo largo del mismo gradiente altitudinal. Las respuestas a las siguientes preguntas constituyen objetivos específicos de este estudio: ¿Cambia la inversión relativa de fotosintatos entre la parte aérea y la parte subterránea a medida que varían los factores ecológicos relacionados con la altitud? ¿Difiere la producción primaria neta total a distintas alturas? ¿Cuál es la tasa de renovación de la biomasa aérea y subterránea? ¿Varía con la altitud? ¿Varían estacionalmente las concentraciones de los nutrientes principales, N, P, K y Ca, en la materia seca? ¿Cómo es la distribución de la biomasa y la asignación de nutrientes hacia los órganos aéreos y subterráneos en estos pastizales? ¿Existen diferencias en el contenido de nutrientes y ciclado de los mismos en los pastizales ubicados a diferente altitud?
ЦерквиВостокапредкрестоноснымправителемзаморскойземли:князьБоэмундIVодноглазый ихристианеЛеванта
Authors: Brun S.P.
Published: August 2019

The article is dedicated to the ecclesiastical policies of one of the most outstanding Crusader rulers of Outremer Bohemond IV the Oneeyed, Prince of Antioch (1198 1199/ 1201 1216/1219 1233) and Count of Tripoli (1187 1233). During the long years of his reign, Bohemond IV was excommunicated several times by both the Pope of Rome and the Latin Patriarchs in the East. He spent a major part of his campaigns fighting Christian, rather than Muslim adversaries. He was guilty of persecuting Latin clergymen, fighting an open war with the Knights Hospitaller, of murdering the Latin Patriarch of Antioch. At the same time, Bohemond IV went much farther than his predecessors in patronizing and contacting the Eastern Christian communities. He allowed his son Philip to join the Armenian Apostolic Church. With a significant part of his nobles and retinue he accepted sacraments and took part in church services, performed by Byzantine and Melkite clergy. Moreover, he reinstated the Greek Orthodox Patriarchate of Antioch in the Levant an act which had lasting consequences, and whose legacy outlived both Bohemond IV and the Crusader domination in the East. The acts and policies of Bohemond IV reveal an entirely new phase of Crusader interaction with the Christian East, a phase that breaks a great number of stereotypes and thus has immense significance for our understanding of Medieval History

Статья посвящена церковной политике одного из самых выдающихся крестоносцевправителей УтремераБоэмунда IV одноглазого, князя Антиохийского (11981199/ 12011216/12191233) и граф Трипольский (1187 1233). За долгие годы своего правления Боэмунд IV был несколько раз отлучен от церкви обоими Папой Римским и латинскими патриархами на востоке. Он провел большую часть своих кампаний, сражаясь с христианскими, а не мусульманскими противниками. Он был виновен в преследовании латинских священнослужителей, в открытой войне с рыцарямигоспитальерами, в убийстве латинского Патриарха Антиохии. В то же время Боэмунд IV пошел гораздо дальше своих предшественников в покровительстве и контактах с восточными христианскими общинами. Он позволил своему сыну Филиппу присоединиться к Армянской Апостольской Церкви. Со значительной частью своей знати и свиты он принимал таинства и принимал участие в церковных службах, совершаемых византийским и Мелкитским духовенством. Более того, он восстановил греческий православный патриархат Антиохии в Леванте акт, который имел длительные последствия, и чье наследие пережило как Боэмунда IV, так и господство крестоносцев на востоке. Действия и политика Боэмунда IV раскрывают совершенно новую фазу взаимодействия крестоносцев с христианским Востоком, фазу, которая ломает множество стереотипов и поэтому имеет огромное значение для нашего понимания средневековой истории
Обзорновейшихпубликаций,посвященныхэпохепатриархаМакарияIIIаз-За‘имаиПавлаАлеппского
Authors: Panchenko K.A.
Published: August 2019

Such a seemingly highly specialized publication as the publication of one of the lists of Macariuss Travels, caused, however, a very emotional reaction in the Ukrainian scientific community. Kiev Turkologist A. I. Galenko, bringing, it seems, some personal accounts with the Institute of Oriental studies. A. Krymsky, made a sharply critical review of the publication.21 The accusations against the different nuances of the translation of the source and the comments to it, largely imagined, ended with a conceptual accusation that the book is published in Ukrainian language, and on the rosascoradyanskoi lingua franca that, coupled with the mention zbrojna agrees Russie22, it looks like a political denunciation. In such a surprising way, the Patriarch of Antioch and his son,the archdeacon, who witnessed political upheavals in Eastern Europe three and a half centuries ago, were involved in todays boiling passions. In conclusion, I would like to wish all the researchers who participated in the Makariev Project a successful completion of the work on the publication of this main work of ArabChristian literature of the New time, as well as new achievements and discoveries in the field of studying the Christian East.

Такая, казалось бы, узкоспециальная публикация, как издание одного из списков Путешествия Макария , вызвала, тем не менее, весьма эмоциональную реакцию в украинских научных кругах. Киевский тюрколог А.И. Галенко, сводя, похоже, какието личные счеты с Институтом востоковедения им. А. Крымского, выступил с резко критической рецензией на публикацию21. Упреки в отношении различных нюансов перевода источника и комментариев к нему, большей частью надуманные, завершились концептуальным обвинением в том, что книга издана не на украинском языке, а на росiйськорадянськой lingua franca , что, вкупе с упоминанием збройно агресi Росi 22, похоже на политический донос. Таким удивительным образом антиохийский патриарх и его сынархидиакон, бывшие свидетелями политических потрясений в Восточной Европе три с половиной века назад, оказались вовлечены в сегодняшнее кипение страстей. В заключение хочется пожелать всем исследователям, участвовуюшим в Макариевском проект, успешного завершения работы над изданием этого главного произведения арабохристианской литературы Нового времени, а также новых свершений и открытий на поприще изучения Христианского Востока.
Regulation of ecosystem services exploitation for potential competing stakenholders in Indiga advanced development region
Authors: Evseev Alexandr , Krasovskaya Tatiana , Tikunov Vladimir
Published: September 2019

Landscape ecological studies supply valuable data for advanced nature management in the Arctic zone of the Russian Federation. The recently adopted State program for advanced economic development of this zone outlined eight regions for such activities. Our study area Indiga belongs to Nenets advanced economic development region. Its landscapes are presented by rolling and hilly plains at the coast of the Barents Sea. Different tundra types are the most typical vegetation cover, but forest-tundra and even northern taiga are also met. Nowadays Indiga is a small settlement in the mouth of the Indiga river which according to the State program will give rise to a new sea port belonging to the Northern Sea Route infrastructure, railway terminal construction. Dominating nowadays traditional nature management will be completed by transport and residential promoting nature management conflicts emerging from joint exploitation of several ecosystem services by different stakeholders. Such conflicts need elaboration of regulation system. Such regulation is of primary importance for ecosystems with low resilience to technogenic impact which may destroy natural processes of ecosystem services pools reproduction. We present a case study demonstrating the procedure of revealing and mapping of ecosystem services using a landscape map. This is the first step for quoting of ecosystem services exploitation.
MODERN MEDICAL AND SOCIAL
ASPECTS OF POPULATION MORTALITY FROM DIGESTIVE DISEASES
Authors: Nozhkina N.V. , Zaripova T.V. , Bessonova E.N.
Published: August 2019

The aim is to assess the current medical and social aspects of mortality due to digestive organs diseases
on the example of the Sverdlovsk region. Methods are epidemiological analysis, expert, statistical.
Results: mortality rate of the population from the digestive organs diseases in the Sverdlovsk region is
characterized by growth dynamics from 71.9 per 100,000 population in 2012 to 83.6 in 2017 and
exceeding the average Russian indicators. In the structure of total mortality this cause ranks fourth
place (6.0 %) in 2017. The mortality rate from the digestive organs diseases among men is 1.3 times
higher than among women, the rural population is 9.1% higher than the urban population. In the age
and sex composition of the deceased, the age of 30–69 years (69.2 %) prevails, men accounted for
52.3 %, and among the working age – 72.3 %, in the age of older able – bodied more women – 58.2 %.
The structure of death causes is dominated by cirrhosis (33.6 %), alcoholic liver disease (13.8 %),
intestinal vascular disease (12.7 %), gastric ulcer and duodenal ulcer (12.2 %), pancreatic disease
(9.6 %). At working age, 43.5 % died due to liver cirrhosis, 22.8 % – alcoholic liver disease, 12.8 % –
pancreatic disease. Among persons at the age above the working age, the proportion of vascular diseases
of the intestine is higher – 21.3 %, gastric ulcer and duodenal ulcer – 15.1 %. According to sociodemographic
characteristics, persons with low social status prevailed among those who died of digestive
system diseases: primary/secondary vocational education in 47.7 %, 43.5 % without vocational
education; 77.5 % did not work at working age. With expert evaluation in 60.3 % of the medical death
certificates, design and coding defects were detected.