bluuebunny/crossref_metadata_2025 huggingface dataset:
Financial crash with a long memory of volatility: fractional volatility in a bubble atmosphere
Authors: boughabi houssam , qalli yassine el
Published: June 2023

Through this article we had chosen a model that takes into consideration any brutal change in prices, a downfall of prices which we had dealt with using discrete jump processes following the poissonian discrete time version of the Johansen-Ledoit-Sornette (JLS) power model as an economic study of such a phenomenon, besides this we have been so creative by adding a fractionally integrated generalized autoregressive conditional heteroscedastic (FIGARCH) shock to our model to obtain a new framework that should intuitively link crashes in the market to past memory. We went for pricing futures afterwards by discretising the filtration Ft which makes pricing possible using the augmented filtration correctly. Options are priced after in absence of arbitrage using econometrics and approximation. Bitcoin is the material of study where we have chosen a period when prices of bitcoin went down sharply to use the JLS part of our model correctly. Besides the pricing study that was the main problematic of this article, we have touched the economical side by discussing a rescue budget and ought to evaluate it to save the futures market during the bubble and at the day of the crash.
JEL Classification. C58, E44, G13.
‹Praktisch und überfordernd zugleich› − Lernen und Lehren in der Kultur der Digitalität
Authors: Nickel Julia , Ganguin Sonja
Published: June 2023

Unter den Bedingungen der Digitalisierung, die alle Lebensbereiche beeinflusst, verändern sich auch Lernen und Lehren und damit einhergehend Anforderungen an Schule als Bildungsinstitution wie auch an die Aus-, Fort- und Weiterbildung von Lehrpersonen. Dieser Wandel ist keinesfalls mit geänderter technischer Ausstattung oder dem Austausch von Lehrwerkzeugen gleichzusetzen, sondern im Kontext der Mediatisierung als Metaprozess sozialen und kulturellen Wandels bzw. einer durch die Digitalisierung entstehenden Kultur der Digitalität zu verstehen. Der Wandel von Lern- und Lehrkulturen lässt sich auch anhand von Entgrenzungen des Lernens und Lehrens skizzieren. Der vorliegende Beitrag beschreibt Entgrenzungen des Lernens entlang der Dimensionen Lernmittel, Lernzeit, Lernort und Lernraum, soziale Form, Lerninhalt, Institution sowie Biografie und geht auch auf damit einhergehende Entgrenzungen des Lehrens ein. Auf Grundlage einer qualitativen Befragung von Lehramtsstudierenden an der Universität Leipzig aus dem Sommersemester 2020 werden schliesslich Erfahrungen und Einschätzungen der Studierenden hinsichtlich entgrenzten Lernens und Lehrens vorgestellt und damit Perspektiven angehender Lehrpersonen auf das Lernen und Lehren in einer Kultur der Digitalität ersichtlich.
Valor ancestral de los objetos técnicos wiwas en la Sierra Nevada de Santa Marta, Colombia
Authors: Mogollón González Daniel , Maldonado Serrano Jorge Francisco , Angarita Cáceres Rafael Gonzalo
Published: June 2023

El artículo reflexiona sobre el valor del pensar-técnico de los wiwas (uno de los cuatro grupos indígenas que habitan la Sierra Nevada de Santa Marta, un sistema montañoso periférico ubicado al norte de Colombia), a la luz de los conceptos de objeto técnico de Gilbert Simondon, de cosmotécnica de Yuk Hui y del enfoque antropológico del perspectivismo amerindio amazónico propuesto por Eduardo Viveros de Castro. El análisis muestra que esta cultura se configura como decidida a buscar y consolidar la estabilidad cosmológico cosmogónica desde una perspectiva filosófica ancestral propia o shama zhigui. Los tópicos que constituyen la filosofía wiwa pueden ser identificados en los actos y los objetos técnicos, como el suzu, mochila realizada por la mujer, y del dumburru, poporo construido por el hombre. La elaboración, el uso y la relación de estos objetos a nivel individual y social proclaman una visión técnica integral de las potencias de la naturaleza planetaria, lo humano y lo cósmico.
REFORMULASI HUBUNGAN AGAMA DENGAN NEGARA: DIALOG PEMIKIRAN YUSUF AL-QARDHAWY DENGAN ULAMA KLASIK TENTANG POLITIK KENEGARAAN DAN IMPLIKASINYA BAGI PERPOLITIKAN DI INDONESIA
Authors: Mashudi Mashudi
Published: June 2023

This research describes the formulation want state politics and religious ties with the country according to Yusuf al-Ulama Qardhawy and Classical. The results of the analysis of their thinking as outlined in his works, can be explained that Yusuf al-Qardhawy reformulate the concept of the relationship between religion and the state as well as the state political through and isti'ab syumuli method, a problem of how to resolve the impasse in state politics as well as the relationship between religion and state product classical scholars thought. Reformulation of the concept of the relationship between religion and the state is the solution to the stagnation (stagnation) patterns of thought classical scholars. The concept of state politics by Yusuf al-Ulama Classical Qardhawy and there are points in common with the Indonesian state politics in the context of the present though not totally, so that some can be implemented to control the practice of politics in Indonesia lately away from religious ethics.
Os livros escolares no Liceu Maranhense pela imprensa local (1844-1876)
Authors: Velázquez Castellanos Samuel Luis , Castro Cesar Augusto , Souza Mateus de Araújo
Published: June 2023

Neste artigo, analisa-se a dinâmica estabelecida no uso dos livros escolares no Liceu Maranhense via imprensa local, usando os pressupostos teórico-metodológicos da história cultural para captar a materialidade dos artefatos como produtos e discursos. Cruzam-se normas instituídas, práticas recorrentes e inovações que acompanharam os programas de ensino via reformas para a manutenção do mercado escolar. Conclui-se que liceístas/autores se adequaram aos ideais de escolarização e conceitos técnicos, segundo as armaduras conceituais em voga, para além da própria representatividade, como intelectuais, garantindo a aprovação, a indicação e o consumo das obras na instrução e a concorrência com produções nacionais e internacionais.
Synthesis of 1,2-dihydropyridine, Arylidene, Hydrazide, and Terthienylnicotinamidine
Hydrochloride Analogs: Theoretical Studies, and Antioxidant Activity
Assessment
Authors: Hammouda Mohamed M. , Abed Nadher A. , Ismail Mohamed A. , Abdel-Latif Ehab
Published: June 2023

:

In the current work, we have utilized the reactivity of N-(4-
acetylphenyl)-2-(4-formylphenoxy)acetamide for the synthesis of novel series of 1,2-
dihydropyridines, Arylidenes, and hydrazides. Our strategies were prolonged for the synthesis
of novel terthienylnicotinamidine hydrochloride salt through a Stille coupling reaction of
6-(5'-bromo-[2,2'-bithiophen]-5-yl)nicotinonitrile with 2-tributyltin thiophene followed by
treatment with lithium trimethylsilylamide and subsequent hydrolysis.

:

The newly prepared structures were well-elucidated by analytical and spectral data
(IR, 1H-NMR, 13C-NMR, MS, and elemental analysis). The theoretical studies of terthienylnicotinamidine
verified that the other atoms that carry a high density of positive values
are considered active centers for the electron acceptor.

:

The novel synthesized compounds were efficiently established by spectroscopic data and elemental analysis.
The antioxidant activity of the synthesized arylidene, hydrazide, and dihydropyridine compounds was assessed
by ABTS•+ free radical assay.

:

The results verified that the transformation of N-(4-acetylphenyl)-2-(4-formylphenoxy)acetamide
(47.6%) into hydrazide analogs provided remarkable antioxidant activity (78.1, and 60.3%).
Synthesis and Diverse Pharmacological Actions of Thiosemicarbazide Analogs: A Review
Authors: Jindaniya Varsha , Mishra Rakhi , Mazumder Avijit , Tyagi Shivani
Published: June 2023

Background:

Thiosemicarbazide is an important substance in the synthesis of pharmacological
and bioactive substances, and it is commonly used in the discovery of new medications. Multiple synthetic
approaches exist for the creation of different thiosemicarbazide analogs, which are then discovered to
treat a variety of diseases.

Objective:

This review paper aims to determine the growing importance of thiosemicarbazide analogs in
various types of sickness by examining various unique synthetic methods that have been described to
manufacture them.

Methods:

To incorporate published research and review papers, a comprehensive review of the literature
from many sources during the past 24 years was conducted.

Results:

This paper summarises the findings of a literature review about the synthesis and biological activity
of thiosemicarbazide and thiosemicarbazone derivatives.

Conclusion:

Numerous new studies on the role of thiosemicarbazide and thiosemicarbazone derivatives,
as well as their methods of production and biological activity for various forms of the disease, are discussed
in this review article.
Prolapsed Uterine Smooth Muscle Tumor of uncertain Malignant Potential: A
Case Report and Review of Radiological Findings
Authors: Jeon Junhyeon , Park Jinyoung , Lee Eunjoo , Han Jiyeon , Kim Dasom , Park Jungwon , Kwag Minha , Yun Suyoung , Jung Soo Jin
Published: June 2023

Introduction:

Uterine smooth muscle tumor of uncertain malignant potential (STUMP) is a rare tumor that arises in the myometrium of the uterus. It is regarded as an intermediate malignant tumor according to the recent World Health Organization classification. Few studies have reported the radiologic findings of STUMP, and the differentiation of STUMP from leiomyoma remains controversial.

Case Description:

A 42-year-old nulliparous female presented at our institution with massive vaginal bleeding. Radiological studies, including ultrasonography, computed tomography (CT), and magnetic resonance imaging, revealed an oval-shaped mass with well-defined margins in the uterus protruding into the vagina. The patient underwent a total abdominal hysterectomy, and the final pathology was confirmed as STUMP.

Conclusion:

Distinguishing STUMP from leiomyomas based solely on radiological findings can be challenging. However, if the uterine mass appears as a single mass lacking acoustic shadowing on ultrasound and demonstrates diffusion restriction with high T2 signal intensity on magnetic resonance imaging, consideration of STUMP may be necessary for proper patient management, given the poor prognosis associated with this tumor.
Identification of Hub Genes in Neuropathic Pain-induced Depression
Authors: Cui Chun-Yan , Liu Ming-Han , Mou Jian , Liao Si-Jing , Liu Yan , Li Qun , Yang Hai , Ren Ying-Bo , Huang Yue , Li Run , Zhang Ying , Liu Qing
Published: June 2023

Introduction::

Numerous clinical data and animal models demonstrate that many patients with neuropathic pain suffer from concomitant depressive symptoms.

Methods::

Massive evidence from biological experiments has verified that the medial prefrontal cortex (mPFC), prefrontal cortex, hippocampus, and other brain regions play an influential role in the co-morbidity of neuropathic pain and depression, but the mechanism by which neuropathic pain induces depression remains unclear.

Results::

In this study, we mined existing publicly available databases of high-throughput sequencing data intending to identify the differentially expressed genes (DEGs) in the process of neuropathic pain-induced depression.

Conclusion::

This study provides a rudimentary exploration of the mechanism of neuropathic pain-induced depression and provides credible evidence for its management and precaution.
Interactions Among Temperature, pH, and Agitation May Cause
Instability in an Oil-in-water Emulsion
Authors: Hatam Saeid , Mohammadinejad Sina , Hatam Gholamreza
Published: June 2023

Introduction:

Two key features of an emulsion, stability and viscosity, are not
only considered dependent on ingredient quantities but also delicately affected by emulsification
conditions, such as pH, temperature, and mixing conditions.

Methods:

In the laboratory, we formulated an O/W emulsion made up of 41% water, 9.8%
silicon (polydimethylsiloxane), 22.1% liquid sucrose (700 mg/ml), 22.1% light liquid paraffin,
and 1.5 to 5% paraffin emulsifier by volume % purposed for large-scale production
as a rubber coating for decorative purposes.

Results:

This emulsion became faulty after large-scale production, while it was fine on the
laboratory scale. This study investigated the probability of a complicated interaction
among pH, temperature, solutes, and agitation intensity on the stability and viscosity of our
emulsion by focusing on sugar degradation effects on these parameters. This emulsion was
made in two different temperatures and agitation rates, and the emulsification time was 20
minutes for all samples. The critical roles of appropriate pH regulators or buffers in the
stability were also investigated.

Conclusion:

It was found that applying intense agitations at 1500 rpm during emulsifications
in high temperatures may lead to absurdly high emulsion viscosity, accompanied by a
sharp pH fall.
Applications of Blockchain in Cyber Security Industry
Authors: Gupta N. , Agrawal R.
Published: June 2023

A blockchain is a decentralized record that is used to securely transfer digital
currencies, make agreements, and trade. Everyone in the system goes to the most recent
duplicate of the encoded record in order to authorize another transaction. A blockchain
record is a collection of all prior bitcoin exchanges. Fundamentally, it is a suitable
database that keeps up with a continually developing, highly organized information
structure of blocks that hold a large number of individual transactions. Blockchain
innovation has seen adoption in a variety of organizations, most notably in the use of
digital currency. Regardless, innovation is useful in cyberspace. This chapter examined
a few application cases of Blockchain in the cybersecurity industry. A majority of
specialists are working on the acceptance of blockchain to safeguard IoT (Internet of
Things) devices, systems, and information. The chapter has examined the methods
proposed by previous analysts through which blockchain can carry the expense of
security. Finally, the chapter has proposed the future of a single blockchain for building
cyber security applications for coordination and consistency among security
arrangements.
Solutions for DDoS Attacks on Cloud Environment
Authors: Bhardwaj Akashdeep
Published: June 2023

The internet has become the key driver for virtually every organization’s
growth, brand awareness, and operational efficiency. Unfortunately, cyber terrorists
and organized criminals know this fact too. Using a Distributed Denial of Service
attack, they can deny corporates and end-users internet access, make the website go
slow, and deny access to corporate networks and data, making them unable to service
legitimate users. It is not just these that are vulnerable; DDoS attacks are diversions.
Due to the increased attack volume, collateral damage is becoming a major cause of
concern – packet loss, delays, and high latency for internet traffic of those whose
network traffic traverses the WAN saturated by a DDOS attack. DDOS attacks disrupt
services and distract security resources, while other attacks, like fraudulent
transactions, are attempted. Adaptive DDOS attacks are prevalent – attackers attack
traffic on the fly to avoid identification and confuse mitigation plans. Reflective and
Amplification attacks are most common – leveraging misconfigured DNS, NTP, and
other network resources by spoofing source IP addresses. The bitter reality is that for
cloud computing to be useful, it has to be exposed to insecure WANs and the public
internet. With Cloud services presence being advertised and the interfaces defined,
unauthorized attacks would always look to target the services.
A Guided Web-Based Intervention Targeting Procrastination in College Students: Protocol for an Open Trial
Authors: Ozmen Sevin , Amarnath Arpana , Struijs Sascha , de Wit Leonore , Cuijpers Pim
Published: June 2023

Background

Academic procrastination is a widespread problem among college students. It is linked to poor academic performance and increased college dropout intentions, as well as several mental health problems such as depression, anxiety, and stress. Guided web-based interventions can help reduce procrastination. However, guidance by professional clinicians draws upon valuable and limited societal resources, and a more efficient, scalable form of guidance is needed. Guidance by trained clinical psychology students has not yet been examined.

Objective

The aim of this open trial is to examine the feasibility and acceptability of a web-based procrastination intervention for college students under the guidance of student digital coaches (e-coaches).

Methods

We developed a single-arm trial of a guided web-based intervention targeting procrastination for the Dutch student population. Guidance is delivered by trained clinical psychology students asynchronously in the form of textual feedback on intervention progress, with the aim of supporting and motivating the participant. Participants are recruited at 7 Dutch universities. Primary outcomes are intervention satisfaction, usability, and adherence, which are assessed by the Client Satisfaction Scale (CSQ-8), System Usability Scale (SUS-10), and number of completed modules, respectively. The primary outcomes will be examined by calculating descriptive statistics. Secondary outcomes are e-coach satisfaction and changes to procrastination, depression, stress, and quality of life from pre- to posttest and follow-up.

Results

The project was funded in 2019, and recruitment began in January 2021. As of May 2023, a total of 985 participants were enrolled, of which 372 had completed the posttest and 192 had completed the follow-up. The expected date of analysis and publication of the results is 2024.

Conclusions

The results are expected to contribute to the body of literature regarding eHealth in 3 ways. First, we will examine whether students who procrastinate adhere to and are satisfied with an eHealth intervention targeting this problem. Second, we will explore whether an intervention targeting procrastination can also decrease depression and stress. Lastly, we will investigate whether trained psychology students can effectively guide their peers in web-based interventions. Given the shortage of licensed psychologists, exploring alternative sources of guidance is much needed in order to provide students with the mental health support they need.

International Registered Report Identifier (IRRID)

DERR1-10.2196/44907
Confucian Sports Thought: Combining Sports with Education
Authors: YAO TANG , YANG CHENG , YAJun ZHOU
Published: June 2023

Since the reform and opening up, China has developed rapidly, and people’s ideas, ethics, and values have been constantly changing. Because of the changes in the morals and values of students’ parents, it has also brought a significant impact on education. They only focus on student’s academic achievements, and students’ physical quality and moral education are ignored. How should school education do? China’s Confucianism may inspire us. Confucianism attaches importance to moral, intellectual, and physical education, and emphasizes the all-round development of human character, intelligence, and body. Confucianism integrates ethical code into physical activities and achieves the purpose of education. Confucianism inspires us that school physical education should not only focus on improving students’ physical quality but also pay attention to its educational function.
Analysis of the Conventional Steel Building and Pre-Engineered Building Structures for Various Bay Lengths
Authors: Upadhyay Shubham
Published: June 2023

Abstract: Comparing PEB structures to conventional structures is the main goal of this study. Pre Engineered Buildings (PEB) are constructions that are manufactured and assembled on site. This study assesses both traditional steel structures and preengineered structures. Usually, industrial buildings are built using this kind of structural principle. An industrial structure with 5 and 6 m-long bays is under consideration. STAAD PRO software is used for structure analysis. In this study, the maximum reaction, maximum stress analysis, and maximum axial force results for conventional steel structures and pre-engineered structures with bay lengths of 5 and 6 metres are examined and compared. We consequently conclude that PEB is preferable to CSB.
Formulation and Evaluation of Herbal Facewash Preventing Dermatological Problem
Authors: Das Koushik
Published: June 2023

Abstract: Facewash is one type of cosmeceuticals as well as semisolid dosage forms used for external purposes. It is applied on the skin surface to protect the skin from various microbial attacks. This type of cosmeceutical is also used to clean different types of skin problems like skin acne, skin pimples, skin rashes, dark circles, black spot, oily skin, skin discolored, etc. In this study, we have formulated one herbal face wash containing different extraction of herbal materials like fresh aloevera gel, leaves of neem, turmeric, lemon juice, Fresh leaves of Tulsi, fresh pudina leaves, Chandan, liquorice, Honey, Coffee, Multani mati, rose water as well as various types of excipients like sodium CMC, sodium lauryl sulphate, sodium benzoate, glycerol and distilled water. After formulation study we focused the evaluation cum validation of the formulated new herbal facewash like testing of pH ,Spreadability test, foam forming test, etc.
Reclamation of Saline Agricultural Land
Authors: Patil Amrut
Published: June 2023

Abstract: The sustainability of (irrigated) agriculture in India is threatened by waterlogging, soil salinity, and alkalinity. To reverse declining agricultural productivity, a combination of surface and subsurface drainage, supplemented by improved irrigation management, has been identified as the most appropriate strategy. But subsurface drainage for salinity control is costly. Therefore, its sustained agricultural production benefits must be thoroughly investigated to establish its technoeconomic feasibility. The present study attempts to do this by analysing the cost of installing subsurface drainage, the direct onfarm benefits of subsurface drainage, and the financial feasibility of subsurface drainage. The study site selected for this study is Uran Islampur (Maharashtra State). The results say land use will intensify if drainage is installed because a sizeable area of formerly fallow land was brought under cultivation. It also says that the cropping pattern will be changed in favour of more remunerative crops, and crop yields will increase. These immediate gains from drainage are helping to increase land productivity, gainful employment of the farmers and, hence, farm income. The financial and economic feasibility of drainage in waterlogged and saline areas looks favourable, provided that sufficient water is available for leaching and irrigation and that a sustainable solution for the disposal of the low-quality drainage effluent is found. Concerning the latter, creating ponds to store drainage effluent temporarily is technically possible while not threatening the financial feasibility of the investment in drainage.
Mengintegrasikan Etika Islam Dalam Dilema Etis Dan Pendidikan Akuntansi
Authors: Amalia Elsa , Srimaya Laksita Sela
Published: June 2023

This study aims to integrate Islamic ethics in ethical dilemmas and accounting education in order to help accountants to behave ethically based on Islamic guidelines and eventually decrease the desire to behave fraudulently and monopolize financial statements. This study utilizes a qualitative research by applying literature study methods according to the library research method book. This study uses data, which is articles related to the topics discussed taken from accounting journals. The results of the study show that there is a need to reform the current accounting rules to harmonize the ethical thinking of accountants. Furthermore, the integration of Islamic ethics in ethical dilemmas and accounting education is crucial, so that accounting students in University become more aware of ethical behavior. Finally, the integrity of Islamic ethics as outlined in professional education and training programs is able to instill a good ethical mentality from the accountants, so as to provide them in facing ethical dilemmas.
Competence, Professionalism, Audit Experience and Auditor's Ability In Detecting Fraud
Authors: Wicaksono Agung Prasetyo Nugroho
Published: June 2023

This study aims to examine the effect of competence, professionalism, and audit experience on the auditor's ability to detect fraud. This type of quantitative research with respondents are inspectors and auditors at the Inspectorate of Batu City. Determination of the number of samples is done by non-probability sampling method with purposive sampling technique. The data in the study used primary data taken directly to the respondents through a given questionnaire. The research data were analyzed using the outer model and inner model tests with the help of the Smart Partial Least Square (PLS) version 3.3.9_64bit software program. The results obtained in this study are competence has a positive and significant effect on the auditor's ability to detect fraud, professionalism has a positive and significant effect on the auditor's ability to detect fraud and audit experience has a positive and insignificant effect on the auditor's ability to detect fraud. Future research is expected to add independent variables from external factors that can affect the auditor's ability to detect fraud such as red flags, workload, and time pressure to obtain valid data.
Konsep Corporate Social Responsibility Berbasis Pangadarang Wija To Luwu
Authors: Sahib Nurdea , Rismawati Rismawati , Rusli Andika , Hapid Hapid
Published: June 2023

This study aims to reconstruct the concept of CSR with the values contained in pangadarang so that it can provide a new perspective on the concept of CSR. This aim proposes an interpretive paradigm and ethnographic method to understand and reconstruct the concept of CSR with the local wisdom of Pangadarang. This study uses two methods in ethnography, namely the step-by-step method and the inculturative critical ethnography method. The customary order contains customary rules “Pattuppui ri-Ada'e, Mu pasanrei ri-Syara'e”, an affirmation to always be sami'na wa atho'na against God's commands and always uphold the values of local wisdom in order to be human. who is dignified and always has hablum minannas. Research shows that companies must uphold the values of sipakatau, sigunakannge' and sipakalebbi in establishing social relationships. To protect the surrounding environment, companies must also apply the makkasiwiang culture as a quality control in managing nature. This application can be a social capital that can bring benefits to the company.
Effect of microencapsulated Lactobacillus reuteri under simulated gastric conditions and its inhibition on Listeria monocytogenes
Authors: Jurado-Gámez Henry Armando , Cerón-Córdoba Jhon-Fredy , Bolaños-Bolaños Juan Carlos
Published: June 2023

Food-borne diseases (FDB) are responsible for causing approximately 600 million illnesses and 420,000 deaths per year. Biologically related FBDs are typically associated with ubiquitous microorganisms, with bacteria such as Li. monocytogenes, Escherichia coli, Salmonella and Staphylococcus aureus being frequently implicated. The use of probiotics is limited by adverse conditions, that can impair the stability of La. reuteri and the evaluation of its probiotic properties and effects on pathogenic bacteria. Therefore, it is crucial to develop effective strategies to protect probiotics during their use. This study was conducted aiming to determine the effect of microencapsulation by spray drying technique on the probiotic viability of La. reuteri on Li. monocytogenes under simulated gastric conditions. The research involved reconstituting, planting, and inoculating La. reuteri and Li. monocytogenes; determining fermentation kinetics; conducting spray drying microencapsulation; studying and characterizing of microencapsulation; testing for exopolysaccharides production; conducting temperature tests; assessing exposure to gastric conditions; and conducting antibiotic susceptibility and inhibition tests. Such investigations allowed the establishment of the exponential phase in Probiotic (PRO) culture medium at 18 h and in De Man, Rogosa and Sharpe agar (MRS) medium at 12 h, exopolysaccharide production positive and growth at different temperatures (1.95x1013 CFU/ml and 2.16x1012 CFU/ml), survival against gastric conditions (greater than 108 CFU/ml) and inhibitory effect of La. reuteri on Li. monocytogenes (halos larger than 2 mm). The probiotic La. reuteri microencapsulated in a binary matrix composed of inulin and maltodextrin expresses probiotic properties against Li. monocytogenes, which is responsible for FBD and great stability after undergoing simulated gastric conditions.
Metabolic indicators and their relationship with reproductive efficiency in dairy cows in the high tropics
Authors: Zambrano-Burbano Gema Lucia , Campos-Gaona Rómulo , Apráez-Guerrero Edmundo
Published: June 2023

The specialized herds of the high tropics of Nariño are characterized by semi-intensive breeding models, that is, feeding based on grazing and supplementation. The objective was to analyze the milk production of grazing Holstein cows under conditions of the high tropics, taking into account the energetic and protein metabolites, and their relationship with the dry matter intake (CMS/Kg/d), the body condition (BC), and the reproductive variables. Three periods of lactation were evaluated, thus, between 4-10 days (P1), 45-55 days (P2), and between 185-200 days (P3). The investigation was carried out in four dairy production farms. The forage supply consisted of a mixture of Lolium hybridum, Cenchrus clandestinus Hoschst ex Chiov, Holcus lanatus and Trifolium repens, plus commercial concentrate. A total of 24 Holstein animals (six per productive system) from three births onwards were used, from which blood samples were obtained to determine: non-esterified fatty acids (NEFA), beta-hydroxybutyrate (BHB), triglycerides, cholesterol, glucose, total protein (PT), and blood urea nitrogen (BUN). The results showed that milk production during P1 is influenced by CC and body weight (Kg) by +0.04 liters of milk per unit of change in this variable. In P2, the positive incidence variables were PT, BUN, glucose, NEFA, BHB, triglycerides, and cholesterol, and in P3, the increase in CMS made it possible to show that as lactation progresses in more than 180 days, the animals substantially improve their body condition; likewise the NEFA and BHB indicators are related to a better reproductive response.
Examination of Physical Education and Sports Teachers' Anxiety Regarding Their Professions
Authors: TUNCEL Yasemin , YIKILMAZ Ahmet
Published: June 2023

Increasing the quality of educational organizations that shape the future generations of society can only be possible by eliminating existing problems. Some of the important problems related to education are the self-professional concerns experienced by teachers and teacher candidates, who are the leading roles of educational organizations. The increase in professional anxiety negatively affects the performance of teacher candidates and is a state of uneasiness that threatens their biological health. In this respect, it is important to reveal the level of professional anxiety of teacher candidates. The aim of this study is to examine the anxiety levels of physical education and sports teacher candidates towards their profession. The population of the research consists of physical education and sports teacher candidates studying in physical education and sports colleges of universities (Iğdır University and Kafkas University) in the 2020-2021 academic year, and the sample group consists of 345 (187 male, 158 female) teacher candidates selected on a voluntary basis. As a data collection tool in the research; The "Vocational Anxiety Scale for Pre-Teachers" developed by Cabi and Yalçınalp (2013) was used. SPSS 22.0 program was used in the analysis of the data. After testing for normality and homogeneity, t-test was performed for independent groups in paired groups, and one-way analysis of variance and LSD post-hoc test correction was performed for variables with more than two groups. Values are presented as mean and standard deviation and analyzed at 0.05 significance level. As a result of the research; It is seen that there is no significant difference in the anxiety levels of physical education teacher candidates towards their profession in terms of men and women. In terms of age variable, it was observed that the professional anxiety levels of teacher candidates aged 27 and over were higher than other age groups, while a significant difference was found in terms of the type of high school graduated from. However, no significant difference was observed in terms of the class variable studied. It was determined that the physical education and sports teacher candidates with a high academic grade point average had higher occupational anxiety than those with a low academic grade point average. In terms of mother's education level variable; It has been observed that primary, secondary and associate degree graduates have higher anxiety than high school and undergraduate graduates, and there is no significant difference in terms of the father's education level variable. It was concluded that there was no significant difference between the professional anxiety levels of physical education and sports teacher candidates in terms of income level.
Sekiz Haftalık Spor Tırmanışı Eğitiminin Kaygı, Mutluluk ve Çeşitli Motorik Değişkenler Üzerine Etkisi
Authors: DEMİRELLİ Mehmet Murat , ÖKTEM Tuncay
Published: June 2023

Bu çalışmanın amacı, spor tırmanış eğitiminin daha önce spor tırmanış deneyimi olmayan bireyler üzerindeki fiziksel ve psikolojik etkilerinin araştırılmasıdır. Çalışmada, daha önce spor tırmanış yapmamış üniversite öğrencilerinden oluşan bir örneklem seçilmiştir. Araştırma hipotezini test etmek için 8 haftalık bir spor tırmanış eğitim programı oluşturulmuş ve katılımcılara uygulanmıştır. Araştırmaya 14'ü deney, 14'ü kontrol grubu olmak üzere 28 gönüllü katılmıştır. Deney grubu 8 hafta boyunca haftada 3 kez spor tırmanış eğitimine katılırken, kontrol grubu bu süre zarfında herhangi bir fiziksel aktivitede bulunmamıştır. Ön-test son-test kontrol gruplu deneysel desenin kullanıldığı çalışmada antropometrik ölçümler, performans testleri, Oxford Mutluluk Ölçeği ve Durumluk-Sürekli Kaygı Envanteri'nin sürekli kaygı boyutu kullanılarak veriler toplanmıştır. Bulgular, deney grubunun dikey sıçrama, hem sol hem de sağ el için kavrama gücü, sırt kuvveti ve sürekli kaygıda istatistiksel olarak anlamlı bir gelişme ortaya koymuştur. Mutluluk ve esneklikte olumlu bir gelişme olmasına rağmen, bu değişiklikler istatistiksel olarak anlamlı bulunmamıştır. Bu çalışma, 8 haftalık spor tırmanış eğitiminden sonra sürekli kaygı ile ilgili önemli istatistiksel sonuçlar elde edilmesi bakımından daha önce yapılan çalışmalardan farklılaşmaktadır. Ek olarak, deney grubundaki tüm katılımcıların sol el pençe kuvvetinde bir artış gözlemlenmiştir.
Men’s s Health in Nursing Practice: A Survey of Senior Nurses
Authors: Whitehead Michael , Hayes Mary , Whitehead Christina
Published: June 2023

Background: Australian men are likelier to die younger than women, often from preventable diseases or conditions. Gendered health promotion has improved men’s engagement with health services, with nurses playing a central role in information and healthcare design. The primary aim of this research was to survey senior clinical and executive nurses on their understanding and perception of men’s health.

Methods: A cross-sectional quantitative online survey was attended by senior nurses within a single hospital setting in metropolitan Sydney between June 2022 and July 2022. Sampling selection was conducted of nurses who currently hold senior clinical or management roles within the health district (Nurse Manager, Nurse Unit Manager, Director of Nursing, Nurse Practitioner, Transitional Nurse Practitioner, Clinical Nurse Consultant, Clinical Nurse Specialist, Nurse Educator, Clinical Nurse Educator) with descriptive analysis applied to interpret the data sets.

Results: A total of 84 responses were received, representing a 33% survey participation rate. A key finding was that 89.1% of senior nurses believed that traditional masculine traits affected health-seeking behaviour. However, 60.2% had not discussed men’s-specific agencies with male patients, and 33.7% of senior nurses believed that gender was not a determinant of health. There was strong endorsement (74.6%) for a men’s health education program to be developed specifically for nurses.

Conclusion: The results of this single-site online survey of senior nurses illustrate that while foundational understandings of gender as a determinant of health were divided, there remained strong endorsement for targeted men’s health promotion to patients and the development of men’s health educational programs to support nurses in providing holistic care for their male patients.
Hub and spokes in intellectual disability mental health support
Authors: R Karen Fisher , Purcal Christiane , Weise Janelle , O’Shea Peri , Trollor Julian
Published: June 2023

Purpose The distribution of specialist health services is usually uneven
by location due to limited resources, which is a problem for people with
complex needs. In this context, the research addressed the question: How
can a hub and spoke model offer appropriate (available, accessible,
acceptable and quality) services for people with intellectual disability
and mental health needs? Methods The research applied the question to
point-in-time qualitative interview data about services for people with
intellectual disability and mental health needs in the Australian state
of New South Wales (NSW). The interview data were from a larger
mixed-methods evaluation of a time-limited intervention (2018-2020).
Purposeful sampling was used to recruit 25 program consumers, families
and service providers for semi-structured qualitative interviews, and 14
other stakeholders for focus groups and interviews. Topics included
their experience of the process and outcomes of the intervention. Data
were analyzed against a hub-and-spoke model analytical framework.
Results The research found that the appropriateness of health services
benefited from funded, local positions. These local professionals
liaised between local mental health, health and disability providers.
They also liaised with other local areas and with centralized,
specialist intellectual disability mental health services. Conclusions
The implication is that specific local positions can work as a bridge
between generic and specialist services to improve the availability,
access, acceptability and quality of services for people with specific
support needs. This program worked well in a geographically large area
with a scattered population and decentralized health system.
Multiple factors influence telomere length and DNA damage in individuals residing in proximity to a coal-burning power plant
Authors: Souza Melissa Rosa de , Garcia Ana , Dalberto Daiana , Picinini Juliana , Touguinha Luciana , Salvador Mirian , Silva Juliana da
Published: June 2023

Coal is a mixture of several chemicals, many of which have mutagenic and
carcinogenic effects and are a key contributor to the global burden of
mortality and disease. Previous studies suggest that coal is related to
telomeric shortening in individuals occupationally exposed, however
little is known about the effects of mining and burning coal on the
telomeres of individuals living nearby. Therefore, the primary objective
of this investigation was to assess the impact of proximity to coal
power plants and coal mines on the genomic instability of individuals,
while also exploring potential associations with individual
characteristics, oxidative stress, inflammatory responses, and the
presence of inorganic elements. This study involved 80 men participants
from three cities around a thermoelectric power plant and one city
unexposed to coal and byproducts. DNA was extracted from peripheral
blood samples obtained from each participant, and the length of
telomeres (TL) was assessed using quantitative real-time polymerase
chain reaction (qPCR) methodology. No significant difference was
observed between exposed individuals (6,227 ± 2,884 bp) when compared to
the unexposed group (5,638 ± 2,452 bp). Nevertheless, TL decrease was
associated with age and risk for cardiovascular disease. Longer telomere
length was found to be linked with increased concentrations of Si and P
in blood samples. No correlations were observed between TL with comet
assay, micronucleus test, oxidative stress, and inflammatory results.
Additional research is required to ascertain the potential correlation
between these changes and the onset of diseases and premature mortality.
Development and validation of a novel UFLC-MS/MS method for the detection of biomarkers of organophosphate pesticide metabolites in urine.
Authors: Sinha Sukesh Narayan , Kumar Dileshwar , Ungarala Ramakrishna , KVasudev *
Published: June 2023

Rationale: Occupational or environmental exposure to
organophosphate pesticides widely used worldwide can lead to significant
health problems. Monitoring the levels of dialkyl phosphates (DAP)
metabolites in human urine is a common biomarker for assessing such
exposure. In this study developing a new screening method using
ultra-fast liquid chromatography coupled with tandem mass spectrometry
(UFLC-MS/MS) to detect six DAP metabolites in human urine.
Methods: Three different compound extraction methods, namely
QuEChERS, lyophilization, and liquid extraction, were compared in this
study. The performance of each method was evaluated based on the
recovery rate. The liquid extraction method provided better results and
required only 20 minutes for analysis. The recovery rate, repeatability
and reproducibility were determined to assess the method reliability.
Additionally, the limits of detection and limits of quantitation were
established to determine the lowest concentrations at which the method
could reliably detect and quantify the DAP metabolites.
Results: The liquid extraction method demonstrated superior
performance compared to the other extraction methods, with a high
recovery rate ranging from 93% to 112%. The repeatability (RSD) values
ranged from 0.62% to 5.46%, indicating good precision within the same
laboratory. The reproducibility (RSD) values ranged from 0.80% to
11.33%, indicating acceptable variability between laboratories or
analysts. The LOD values ranged from 0.0201 ng/mL to 0.0697 ng/mL, and
the LOQ values ranged from 0.0609 ng/mL to 0.2112 ng/mL, indicating the
method’s sensitivity. Conclusions: The developed UFLC-MS/MS
method are sensitive, and selective technique for detecting six DAP
metabolites of organophosphate pesticides in human urine. The method
successfully analysed 150 urine samples from farmers and non-farmers,
demonstrating its applicability in biomonitoring studies. This method is
particularly advantageous as it requires fewer samples, chemicals,
materials, and time, making it an efficient and reliable approach for
assessing occupational or environmental exposure to organophosphate
pesticides.
An expert review of environmental heat exposure and stillbirth in the face of climate change: clinical implications and priority issues
Authors: Bonell Ana , Part Cherie , Okomo Uduak , Cole Rebecca , Hajat Shakoor , Kovats Sari , Sferruzzi-Perri Amanda , Hirst Jane
Published: June 2023

Exposure to extreme heat in pregnancy increases the risk of stillbirth.
Progress in reducing stillbirth rates has stalled, and populations are
increasingly exposed to high temperatures and climate events that may
further undermine health strategies. This narrative review summaries the
current clinical and epidemiological evidence of the impact of maternal
heat exposure on stillbirth risk. 19 out of 20 studies found an
association between heat and stillbirth risk. Recent studies based in
low- middle- income countries and tropical settings add to the existing
literature to demonstrate that all populations are at risk.
Additionally, both short-term heat exposure and whole-pregnancy heat
exposure increase the risk of stillbirth. A definitive threshold of
effect has not been identified, as most studies define exposure as
> 90 percentile of the usual
temperature for that population. Therefore, the association between heat
and stillbirth has been found with exposures from as low as
>12.64°C up to >46.4°C. The pathophysiological
pathways by which maternal heat exposure may lead to stillbirth, based
on human and animal studies, include both placental and embryonic or
fetal impacts. Although evidence gaps remain and further research is
needed to characterise these mechanistic pathways in more detail,
preliminary evidence suggests epigenetic changes, alteration in
imprinted genes, congenital abnormalities, reduction in placental blood
flow, size and function all play a part. Finally, we explore this topic
from a public health perspective; we discuss and evaluate the current
public health guidance on minimising the risk of extreme heat in the
community. There is limited pregnancy specific guidance within heatwave
planning, and no evidence-based interventions have been established to
prevent poor pregnancy outcomes. We highlight priority research
questions to move forward in the field and specifically note the urgent
need for evidence-based interventions that are sustainable.
지역사회 내 유아학교 학급에서의 Prevent-Teach-Reinforce 모형 적용 평가
Authors: Kulikowski Laura L. , Blair Kwang-Sun Cho , Iovannone Rose , Crosland Kimberly
Published: June 2023

본 연구는 지역사회 내 한 사립 유아학교의 학급 교사 두 명과 4세 유아 두 명을 대상으로 개별화 행동중재 과정 모형인, Prevent-Teach-Reinforce (PTR) 모형을 적용한 후 유아학교에서의 그 모형 적용 가능성 및 모형의 잠재적 효과성을 알아보는데 초점을 둔 것이다. 단일사례연구 설계 중의 하나인 일과활동간 중다기초선 설계를 사용하여 팀 중심의 PTR 과정을 통해 개발된 PTR 행동중재를 교사가 실행한 것이 대상 유아의 행동 변화에 어느 정도 영향을 주는지 알아보았고, 추가적으로 연구자의 PTR 과정의 단계적 실행에 따른 절차충실도 및 중재의 사회적 타당도 또한 알아보았다. 연구결과, 교사들에 의한 PTR 중재 실행 충실도는 높았고, 교사들이 실행한 중재는 대상 유아의 문제행동을 감소시키고 일과 및 활동의 참여행동을 증가시키는데 긍정적인 영향을 준 것으로 나타났다. 교사들은 중재의 표적이 되지 않았던 유아에게도 PTR 중재를 적용하면서 PTR 중재의 일반화 가능성을 보여주었다. 참여 교사들은 PTR 중재가 적절하고 수용가능한 것으로, PTR 중재의 사회적 타당도는 비교적 높은 것으로 평가를 해 주었으며, 연구 참여 유아들과 연구에서 적용한 PTR 모형을 알지 못하는 두 명의 관찰자 또한 PTR 중재의 사회적 타당도는 높은 것으로 평가를 해 주었다.
Meta-Analysis and Analysing Quality Indicators of Intervention on Problem Behaviors for Elementary Students with Autism Spectrum Disorders
Authors: Cho Sang In , 오 정민
Published: June 2023

By analysing the study designed for the single-subject of the problems behavior of elementary students with autism spectrum disorders in Korea, this study aims to discuss effective intervention on behavior problems for elementary school students with autism spectrum disorders. First, we examined general trend of studies according to 22 articles' study trend, research problems, subject of study, type of intervention, experimental design, percentage of non-overlapping data, and other qualitative factors related to single-subject design study. Second, we calculated and analysed PND for each factors of effect-sizes of intervention on problem behaviors. Third, we have done quality analysis based on quality indicators which were proposed by Kim Eun Kyoung(2015). Based on the analyses, we fond out that 1)the research of intervention for men was the most, and 2)intervention was done mainly on school, and 3)most of the interventor were experts. Also, a lot of researches excluded linearity of intervention and social validity and most studies used multiple baseline design across subjects for research of intervention on problem behaviors, and interventions mostly were based on cognitive ability and technology-oriented approach. Suggestions of this study were as follows: First, necessity of variety intervention considered child's characters. Second, necessity of evidence-based research. Third, necessity of research that experts and families work together for the intervention in child's problem behaviors. Fourth, necessity of ecological intervention through functional behavior assessment.