bluuebunny/crossref_metadata_2025 huggingface dataset:
Superposition as a Means of Data Encryption in N-Dimensional Value Spaces
Authors: Burgee Tyler
Published: June 2023

The objective of this study was to provide a new method for creating quantum-proof encryption algorithms. I accomplished this by designing a symmetric 2-key cryptosystem that exploits the superposition principle to encrypt data in multi-dimensional value spaces.

   The proposed cryptosystem substitutes characters for frequencies, as determined by two private keys: component wave order key (CWOK) and character transmission order key (CTOK). A CWOK defines the values and theoretical spatial arrangement of frequencies in a complex wave. A CTOK defines the unique arrangement of system characters (i.e., characters in an encoding scheme such as ASCII), determined by a hash function, to identify a user. Combining the CWOK and CTOK, we construct a character-lookup table (CLT), which defines the character-frequency relationships used to generate a substitution cipher. A cipher’s frequency values must be superimposed in accordance with the CWOK. Fast Fourier Transforms are used during the decryption stage to perform complex wave analysis.

   Complex waves can have n! frequency configurations, where n = the number of component frequencies; each CTOK can have a! character configurations, where a = the number of characters defined in an encoding scheme. Therefore, by requiring n ≥128 and using the ASCII encoding scheme (a = 128), there are n!+a!=128!+128!=2*128! possible key configurations for any given cipher. This is approximately 3.330284e+138 times as many key configurations possible with AES 256.

   Exploiting the multi-dimensional nature of complex waves, and combining these techniques with other powerful encryption algorithms used today, it appears likely that we can create a quantum-proof cryptosystem.
Screening putative transcriptional regulators in Francisella tularensis for attenuation using a multifaceted approach.
Authors: Cashbaugh Mariah , Horzempa Joseph , Davis Shania , Delatore Elio
Published: June 2023

Francisella tularensis is a gram-negative intracellular pathogen that produces a severe infection known as Tularemia. RNA-Seq data revealed that in the presence of erythrocytes, several genes encoding putative transcriptional regulators were modulated: FTL_0671, FTL_1199, and FTL_1665. Gene deletion strains were constructed using Francisella tularensis LVS. The objective of this project was to screen these gene deletion strains for attenuation. A multifaceted approach was utilized to determine the level of replication within macrophages and overall attenuation in vivo. Transforming the bacteria with green fluorescent protein allowed a plate reader to visualize and quantify intracellular growth in macrophages. However, inconsistencies in the data from these experiments led to the utilization of a gentamicin protection assay. This protocol provided a more accurate and reliable method of determining intracellular replication. The results of this experiment revealed a significant increase in the replication of FTL_1665 within macrophages. We sought to determine if these results would translate to hypervirulence in a live model. A chicken embryo infection model confirmed that FTL_1665 was significantly hypervirulent in vivo. In the future, we plan to experiment with the upregulation of the target gene to produce an attenuated strain. This gene may also serve as a potential drug target.
Induced Thyrotoxicosis Elicits Protective Effects in Developing Hearts
Authors: Bogunovich Kirsten , Racine Holly
Published: June 2023

Maternal hyperthyroidism effects development in infants and can lead to conditions such as craniosynostosis, exophthalmos, and cardiac hypertrophy. Models for studying maternal hyperthyroidism, or thyrotoxicosis, are limited. Our lab has established an avian model to study the effects of induced thyrotoxicosis on embryonic development. Thyroid hormones (TH) cause inotropic and chronotropic changes in cardiac tissue, including increased cardiac output, increased blood volume, and hypertrophy. Therefore, we wanted to investigate the cardiac changes in our model. Fertilized chicken eggs are injected on embryonic days (E) 11 and 15 with either saline (control) or 25ng thyroxine (T4). Hearts were harvested on day E19, with halves of each sample used for histological staining with Masson’s Trichrome and qRT-PCR analysis. The main objective was to observe systemic effects of our model by studying morphological and genetic changes in the heart following exposure by measuring expression of THRa (TR receptor), ATP2A2 (calcium ATPases), and MYH7(Myosin heavy chain 7). We hypothesized that levels of all 3 markers would be upregulated, since THRaregulates transcription of these other cardiac markers due to fluctuating levels of TH. These are linked to ventricular hypertrophy when upregulated. However, our results contradicted our hypothesis. There was downregulation of all 3 genes, with a significant downregulation in ATP2A2. In combination with other data collected in our lab and related literature, we suspect that there is a cardiac protective effect occurring in the hearts following thyroxine exposure.
Does Eye Color Affect Vision Acuity in a Variety of Light Conditions?
Authors: Varney Tailynn , Henson Kristy
Published: June 2023

Eye color is a physical characteristic that varies from person-to-person. Due to a range of difference in pigmentation of the iris, people with different eye colors tend to see the world differently. For those with lighter eyes, it may be more difficult to see clearly in environments with certain light conditions or intensities. Throughout a person’s life, they encounter several different forms of light ranging from natural sunlight to artificial lighting. In my research, I investigated whether a person’s eye color influences their vision in artificial lighting compared to natural lighting. Preliminary results show that light did influence visual acuity. However, there was no correlation between eye color and light influenced vision changes.   To assess vision, participants were asked to cover each eye and read a Snellen eye chart. This was completed a total of 4 times. Using two separate eye charts, each with a different color background behind the chart, participants were tested at 10 and 20 feet away from the charts. Each test was presented in a room with only artificial light, and outside of the building in natural light.   This information can help individuals ensure that the change in vision, if any, caused by different kinds of light does not negatively influence their everyday life. In extreme situations those with eyes more sensitive to certain types of light could cause harm to themselves or others around them. Having this information about oneself is helpful to all people, not just those with a history of eye issues.
Role of LpnA in Francisella tularensis Susceptibility to Resazurin.
Authors: Beatty Emma , Schmitt Deanna
Published: June 2023

Francisella tularensis is defined by the Centers for Disease Control and Prevention as a Category A bioterrorism agent due to its low infectious dose, high mortality rate, and ease of aerosolization. Given there is no licensed tularemia vaccine in the United States and the possible development and release of antibiotic-resistant F. tularensis strains, there is an urgent need for new treatments against this bacterium. We determined the phenoxazine dye resazurin (Rz) exhibits antimicrobial activity against F. tularensis and other gram-negative bacteria. The mode of action of this compound is not understood, but potential targets of Rz were identified in a high throughput screen for resistant isolates.  Ninety-three percent of the Rz-resistant (Rzr) isolates sequenced contained mutations within the coding regions of FTL_0421 (lpnA), FTL_0895, and FTL_1504 (katG). To confirm mutation of lpnA was contributing to Rz resistance, we introduced a wild-type copy of lpnA into Rzr1 and then assessed the susceptibility of the resulting complemented strain (Rzr1/pABST-lpnA). The minimum inhibitory concentration (MIC) of Rzr1 and Rzr1/pABST-lpnA were similar, therefore, we wanted to confirm we were restoring expression of LpnA in the complemented strain via Western blot analysis. As expected, LpnA was expressed in wild-type LVS but not in Rzr1 due to the genetic mutation. In the Rzr1 strain transformed with pABST-lpnA, we still did not observe expression of LpnA suggesting our complementation strategy was ineffective.  In the future, we plan to take an alternative approach to investigate the role of LpnA in resazurin resistance by creating a lpnA deletion mutant.
The Effect of Dillapiole on the pathogenesis of Escherichia coli
Authors: Bailey Kaitlyn
Published: June 2023

Dillapiole, a compound isolated from the plant, Foeniculum vulgare (Fennel, Hinojo), was previously discovered to have been effective at diminishing virulence factor expression of Francisella tularensis, a gram-negative bacterium with bioterror potential. The purpose of this work is to examine the therapeutic potential of dillapiole on other pathogenic bacteria such as Escherichia coli. E. coli is a motile, rod-shaped, gram-negative bacterium that is typically found in the intestines of animals and humans and can be an opportunistic pathogen. With the increase of multi-drug resistance among various bacteria, it is important for further research on new therapeutic agents. As in previous studies involving F. tularensis, data presented here suggest that dillapiole does not directly diminish the viability of E. coli.  Dubia cockroach infection assays were used to evaluate the ability of dillapiole to dampen the pathogenesis of E. coli.  Roaches infected with E. coli that were subsequently treated with dillapiole exhibited similar survival to those treated with tetracycline.  However, cockroaches that were treated with the vehicle (DMSO) exhibited reduced levels of survival.  This finding suggests that dillapiole might be dampening E. coli pathogenesis or could be modulating cockroach immunity.  Ongoing studies are focusing on the effect of dillapiole on E. coli virulence gene expression (Supported by NIH Grant P20GM103434 to the West Virginia IDeA Network for Biomedical Research Excellence).
FLLL12, a curcumin analog, activates the oxidative stress response pathway in head and neck cancer: implication for chemoprevention.
Authors: AMIN ARM , Lukmon Raji
Published: June 2023

Carcinogenesis is initiated with irreversible genetic mutation due to endogenously derived or carcinogen-induced oxidative stress. Activation of the antioxidant pathways ameliorates oxidative stress, protects cells from carcinogenic insults, and plays a pivotal role in chemoprevention. We have previously reported that FLLL12 is a potent curcumin analog, possesses in vitro and in vivo anticancer activity, and has better pharmacokinetic profiles than curcumin. The current study aims to identify novel pathways activated by FLLL12. MDA686, a head and neck cancer cell line, was treated with FLLL12 for 24h. Total RNA was used for RNA-Seq analysis. 2-fold differentially expressed genes were used for Ingenuity Pathway Analysis to identify the most significantly affected pathways. Real-time qPCR and western blotting were used to confirm the expression of the genes and their protein products, respectively, in normal, premalignant, and malignant cell lines. RNASeq identified 641 genes. Ingenuity Pathway Analysis identified the ferroptosis, the tumor microenvironment, and the oxidative response pathway as the top three most significantly affected pathways. We confirmed the activation of HMOX-1, NQO1, SLC7A11, and GCLC mRNA and proteins in normal, premalignant, and malignant cells. Although these genes are common for ferroptosis and the oxidative response pathway, treatment of cells with ferroptosis inhibitors, ferrostatin-1, and deferoxamine, did not affect FLLL12-induced cell death, suggesting that these genes are associated with the oxidative stress response pathway.  Our results indicate that FLLL12 activates the oxidative stress response pathway in normal, premalignant, and malignant head and neck cancer cell lines and has strong promise for chemoprevention.
Role of FTL_0445 in Francisella tularensis Susceptibility to Resazurin
Authors: Young Emily , Gibson Jordan , McGovern Siena , Beatty Emma , Kelly Claire , Souder Kendall , Rice Justin , Percifield Ryan J. , Primerano Donald A. , Garrison Nicole , Schmitt Deanna M.
Published: June 2023

Tularemia is a potentially fatal disease caused by the Category A bioterrorism agent Francisella tularensis.  Aminoglycosides, fluoroquinolones, and tetracyclines can be used to treat tularemia; however, there is a high incidence of relapse and treatment failures when using these drugs. Furthermore, there is no tularemia vaccine licensed for use in the United States. Therefore, new antibiotics that target F. tularensis are being investigated. A novel family of resazurin-based antibiotics called resazomycins exhibit antimicrobial activity against F. tularensis and other Gram-negative pathogens including Neisseria gonorrhoeae. The mode of action of resazomycins has yet to be determined. To elucidate potential targets of resazurin (Rz), we screened for spontaneous Rz-resistant (Rzr) F. tularensis LVS mutants. Through the screen, 93% of all Rzr mutants sequenced contained mutations within the coding regions of FTL_0421, FTL_0895, and FTL_1504. In addition, 100% of all Rzr mutants sequenced contained a mutation approximately 50bp upstream of the gene FTL_0445. To understand the effect the mutation has on transcription of FTL_0445, RNA was isolated from wild-type LVS and an Rzr mutant (Rzr1). Quantitative reverse transcription PCR revealed FTL_0445 was upregulated in Rzr1 compared to wild-type LVS. To determine the role of FTL_0445 in Rz resistance, a FTL_0445 null deletion mutant is being generated in Rzr1 using standard molecular genetic techniques. Upon completion, the Rz sensitivity of the deletion mutant will be assessed using agar dilution assays. Understanding the role of FTL_0445 in Rz susceptibility would facilitate further development of these compounds as potential treatments for tularemia and gonorrhea.
An Examination of Gunshot Residue and Lead Exposure
Authors: Mullennex Linsee , Henson Kristy
Published: June 2023

This study examines the longevity of gunshot residue (GSR) for lead-based and lead-free ammunition and verifies that lead-free ammunition is truly lead-free. While a GSR presumptive test is not a definitive answer to whether GSR is explicitly present, it gives law enforcement an idea of whether to consider if more expensive testing is needed. This research will also highlight whether different means of examination for GSR in a forensic setting are necessary due to the evolving variety of lead-free ammunition entering the market.

   Switching to lead-free ammunition will significantly reduce lead exposure. Lead shows high toxicity for many organisms but continues to be dumped into the environment in large quantities. Lead poisoning can cause side effects such as anemia, infertility, and vitamin D deficiency.

   Ward’s Gunshot Residue Presumptive Kit and Sherlock Instant Lead Test Kit were used in this research to indicate the presence of lead, barium, and antimony with color change using a specific sequence of chemicals. Ward’s Gunshot Residue Presumptive test was tested during three scenarios in which a firearm was discharged. The Sherlock Instant Lead Test Kit was used to swab all ammunition advertised as lead-free such as the primer, gunshot residue, casing, and bullet.

   In conclusion, Ward’s Gunshot Residue Presumptive Kit was not sensitive enough to use in real-life scenarios and yielded no results. The Sherlock Instant Lead Test Kit confirmed that lead-free ammunition is truly lead-free, reducing lead exposure when firing a gun and potentially creating issues when examining GSR (lead specifically) in forensics settings.
PENGARUH LITERASI DENGAN MODEL INQUIRI TERBIMBING DALAM MELATIHKAN KETERAMPILAN PROSES SAINS SISWA MI NURUL HUDA MOJOKERTO
Authors: Jannah Novaria Lailatul
Published: June 2023

This study aims to study the effect of literacy with a guided inquiry model on the Science Process Skills of MI Nurul Huda Students, Mojokerto Regency. This research uses quantitative research. The type of approach is descriptive quantitative research, namely research to provide an overview of the symptoms, phenomena, or facts studied by describing the values of independent variables, without intending to connect or compare. From the results of the study, the influence of literacy and guided inquiry on the development of students' science process skills has a value of 78.1%, thus the variable indicates a sufficient category. This means that literacy on the development of science process skills is quite influential for students at MI Nurul Huda
PENINGKATAN KEAKTIFAN BELAJAR SISWA MELALUI MODEL PEMBELAJARAN KOOPERATIF TIPE STUDENT TEAM ACHIEVEMENT DIVISION (STAD) PADA SISWA KELAS IV DI SDN 001 BANGKINANG
Authors: Wahyuningsih Sri , Witarsa Ramdhan , Ananda Rizki
Published: June 2023

This research is motivated by the low learning activity of fourth grade students at SDN 001 Bangkinang. One solution to overcome this problem is to use the Student Team Achievement Division (STAD) type of cooperative learning model. The purpose of this study was to describe the increase in student activeness in Class IV SDN 001 Bangkinang. This research method is Classroom Action Research (CAR) which is carried out in two cycles. Each cycle consists of two meetings and four stages, namely planning, implementation, observation, and reflection. The time of the study was carried out from August to September 2021. The subjects of this research were 17 grade IV students, with 8 male students and 9 female students. The collection technique is in the form of documentation, and observation. The results of this study indicate that the learning activity of fourth graders at SDN 001 Bangkinang in the classical completeness pre-action reached 35.29% with an average score of 64,36 criteria (CA), in the first cycle of the first meeting it reached 41.17% with an average score. 68,73 criteria (CA), in the second meeting it increased to 52.94% with an average value of 71,93 criteria (A). In cycle 2, the first meeting increased to 64.70% with an average value of 75,96 criteria (A), in the second meeting it increased to 76.47% with an average value of 80,00 criteria (A). It was concluded that using the Student Team Achievement Division (STAD) type cooperative learning model could increase the learning activity of fourth graders at SDN 001 Bangkinang
PENERAPAN MODIFIKASI PERMAINAN MENGGUNAKAN MEDIA CONE UNTUK MENINGKATKAN HASIL BELAJAR GERAK LOKOMOTOR SISWA SD MIDU GEDONGAN WARU
Authors: Yusroni Moh. , Prastyana Brahmana Rangga , Utomo Gatot Margisal
Published: June 2023

The results of observations that have been made to third grade students at SD Ngingas Minu Waru Midu Gedangan Sidoarjo, there are still many students who are less than optimal in practicing locomotor movements. This can be seen in the results of the assessment of the locomotor range of motion. The purpose of the action research is the application of game modifications using cone media in order to improve locomotor learning outcomes for students at SD Ngingas Minu Waru Midu Gedangan Sidoarjo. The method used in this research is to use a classroom action research design with 2 cycles. The population and sample of the study were 25 grade III students. The research was carried out in four stages, namely planning, implementation, observation, and reflection. The results of the study were analyzed using percentages. The results showed that there was an increase in locomotor movement learning outcomes after applying the game modification with cone media. The increase in learning outcomes occurred in cycle 2 with a percentage of 88% entering the Completed criteria. Based on the results of these studies, it can be concluded that the application of game modifications with cone media can improve locomotor learning outcomes for third grade students of SD Ngingas Minu Waru Midu Gedangan Sidoarjo.
PENGARUH MODEL BALANCED LITERACY TERHADAP HASIL BELAJAR BAHASA INDONESIA PESERTA DIDIK KELAS III SDN SIDOKLUMPUK SIDOARJO
Authors: Izah Inayatul , Baalwi Muhammad Assegaf , Wahyudi Achmad
Published: June 2023

This research was conducted at SDN Sidoklumpuk Sidoarjo. The purpose of this study was to determine the effect of the Balanced Literacy model on Indonesian language learning outcomes for third-grade students at SDN Sidoklumpuk Sidoarjo. This research includes quantitative research where the data generated is in the form of numbers. The research data were calculated using SPSS software version 16. This type of research is quasi-experimental research (quasi-experimental) with a Nonequivalent Control Group Design. Data collection techniques used in this study were interviews and tests. The data analysis technique used a validity test, reliability test, normality test, homogeneity test, and different test t-tests (independent sample test). The results of the study stated that from the results of testing the research hypothesis, there was an effect of the Balanced Literacy Model on Indonesian language learning outcomes in third-grade students at SDN Sidoklumpuk Sidoarjo. This is evidenced by the value on the different t-tests (independent sample test) which shows that sig 0.006 0.05 then Ho is rejected or Ha is accepted. So it can be concluded that the hypothesis Ha states there is an effect of the Balanced Literacy Model on the learning outcomes of Indonesian class III students
EFEKTIVITAS MODEL PEMBELAJARAN ARIAS TERHADAP MOTIVASI DAN HASIL BELAJAR SISWA KELAS IV SEKOLAH DASAR
Authors: Yasin Fajar Nur , Nihayah Ummu
Published: June 2023

This research  aims to determine the effectiveness of using the ARIAS model on the motivation and learning outcomes of fourth grade elementary school students. The research conducted in this research is quantitative research. The method used in this study was a quasi-experimental research design with nonequivalent (pretest and posttest) control group design. The research sample consisted of 60 students consisting of 30 students in class IVB as the experimental class and 30 students in class IVC as the control class. Data was collected using a questionnaire sheet to determine learning motivation and a test sheet to determine student learning outcomes. The data analysis used was t-test analysis with a significance level of 5%. The results showed that: (1) there was an effectiveness of the ARIAS model on learning motivation by obtaining a sig 2 tailed value of 0.009<0.05 and tcount 2.822 > ttable 1.671, (2) there was an effectiveness of the ARIAS model on student learning outcomes by obtaining a sig 2 value tailed of 0.018<0.05 and tcount 2.508 > ttable 1.671. Thus, there is the effectiveness of using the ARIAS model on the motivation and learning outcomes of fourth grade elementary school students.
Pengabdian Masyarakat Penyaringan Air Menggunakan Alat Sederhana untuk Meningkatkan Kejernihan Air di Desa Kedungpeluk Sidoarjo
Authors: Anugrah Munawir Rio , Putrihadiningrum Devika Cherly , Rahmawati Farah , Maghdalena Anisa
Published: June 2023

Clean water is the most important thing in life. Every day, all living things need water to survive. Through clean water, life is naturally healthier. However, it is different from the water in Kedungpeluk Village in Candi Sidoarjo District. the water in the village of Kedungpeluk is cloudy. Kedungpeluk Village, which is surrounded by rice fields and ponds and has a land area of 1,128,665 ha, is due to water conditions that do not work optimally for bathing, cooking, and washing in general. This activity aims to educate the people of Kedungpeluk Village about overcoming water problems and being able to make water filtration. Community service is carried out in stages through a water filtration method that removes suspended substances from water through a porous membrane using a simple device. The community service partner is Kedungpeluk Village in Sidoarjo. The results of the Community Service obtained were that a simple filtering method for well water in the village of Kedungluk was successfully cleaned.
AZERBAYCAN HALK CUMHURİYETİ DÖNEMİNDEKİ ŞUŞA OLAYLARI: AZERBAYCAN GAZETESİNİN MALZEMELERİNE GÖRE
Authors: QULİYEVA Rüxsarə
Published: June 2023

1917'de Rusya'da Şubat burjuva-demokratik devriminden sonra, Ermenilerin Azerbaycanlılara yönelik etnik temizlik politikasının ikinci aşaması başladı (1918-1920). Yine Şuşa dahil tüm Karabağ bölgesi hedef olarak seçilmiştir.

Böylesine karmaşık bir tarihsel dönemde, Mayıs 1918'de Güney Kafkasya'da üç bağımsız cumhuriyetin kurulmasıyla Şuşa'daki Ermeniler ve Azerbaycanlılar arasındaki ilişkiler daha da gerginleşti. Karabağ'ın dağlık kesiminde yaşayan Ermeniler, 22 Temmuz 1918'de "bağımsızlığını" ilan etmeye çalıştı. Tarihsel olarak Azerbaycan halkının yaşadığı Karabağ, Azerbaycan Halk Cumhuriyeti için bir ölüm kalım meselesiydi. Karabağ ve onun merkezi olan Şuşa'nın Ermenilere verilmesi veya Ermeniler lehine herhangi bir karar alınması hiçbir zaman tartışma konusu olmamıştır. Yeni kurulan devlet, diğer alanlarda olduğu gibi ülkenin toprak bütünlüğünün korunması alanında da ciddi zorluklarla karşı karşıya kalmış ve varlığını sürdürdüğü 23 ay boyunca Ermenistan'dan gelen sürekli tehditlere gereği gibi direnmiştir. Hükümetin resmi yayın organı olan Azerbaycan gazetesi bu konuda şunları yazdı: "Bakü ülkemizin vücudunu oluşturduğunda, Karabağ Azerbaycan'ın ruhunu, zevkini oluşturur. Bakü Azerbaycan'ı maddi olarak sağlıyorsa, Karabağ'ın onu manevi olarak desteklediği herkes tarafından bilinmektedir. Azerbaycan Türklerine ruhsal ve manevi zenginlik veren, onları entelektüel ve fikir sahibi yapan Karabağ ve Karabağ'dır dersem, sanırım hiçbir Azerbaycanlı bunu inkar etmez. Bu nedenle Karabağ'ı sımsıkı elimizde tutmak bizim için bir ölüm kalım meselesidir."
Repensar las relaciones internacionales
Authors: Salimena Gonzalo
Published: June 2023

El propósito de esta obra es brindar una actualización del estado del arte y de los marcos teóricos de disciplinas afines a las relaciones internacionales, de manera de otorgar a los lectores, ya sean estudiantes de grado o de posgrado, la posibilidad de actualizarse en campos cada vez más volátiles y dinámicos. Las tres dimensiones temáticas en que se divide el trabajo responden a campos problemáticos que revisten interés en un mundo crecientemente conflictivo, complejo e interdependiente, donde la incertidumbre es una de las protagonistas del sistema internacional. La teoría de las relaciones internacionales debe ayudarnos a proporcionar un diagnóstico y un análisis adecuados para aproximarnos a esa realidad multifacética.
Reformas de la educación técnica y transformaciones productivas
Authors: Hirsch Dana
Published: June 2023

El sistema educativo argentino ha sido objeto de profundas reformas en las últimas dos décadas. En lo que respecta a la educación secundaria técnica, puede identificarse un primer ciclo de transformaciones que avanzaron en la desespecialización y la diferenciación de la educación, a partir de la década de 1990, seguido por un segundo ciclo de reformas que, a partir del año 2005, inicia un movimiento inverso sin revertir totalmente aquellas transformaciones. El desarrollo de la presente investigación pone en discusión diversas explicaciones acerca de cuál es el sentido y el motor de dichas reformas desde la perspectiva de la crítica de la economía política. Se propone, así, reestablecer la unidad entre aquellas que ponen el foco en los cambios productivos y su impacto en las demandas de formación de atributos para el trabajo y aquellas que ponen el foco en los cambios políticos, tanto en la acción estatal como en la acción de diversos sujetos sociales y los enfrentamientos entre ellos.
Trayectorias de reproducción tecnomediada, genética y riesgo
Authors: Vecslir Leila
Published: June 2023

La asociación del término «tratamiento» a las prácticas biomédicas para tratar la infertilidad es frecuente en el sentido común. Sin embargo, lejos de reducirse a la utilización de una o más técnicas biomédicas, las mujeres que recurren a las tecnologías reproductivas para lograr un embarazo despliegan trayectorias en las que entran en juego dimensiones biográficas, discursivas y estructurales.¿Cuáles son los significados en torno a la genética a partir de los cuales se configuran las trayectorias de las mujeres dentro de la medicina reproductiva? ¿Qué tipo de riesgos son identificados y cómo se entrelazan con los modos de significar la genética? ¿De qué modo el contexto social y cultural del interior bonaerense moldea las trayectorias bajo estudio? Los conceptos de trayectorias de reproducción tecnomediada y retóricas de la genética nos permiten comprender que las experiencias de las mujeres con las tecnologías reproductivas comienzan antes de la primera consulta médica.
The Many Layers of Complexity in DBT: Reconstructing a Crucial Theme in the Therapy of "Jane"
Authors: Marks Michael W.
Published: June 2023

This article presents my responses to two Commentaries on my DBT case of "Jane" (Marks, 2022): one by Gillian Galen, Blaise Aguirre, and Julianne Wilner Tirpak (2022); and one by Allison Ruork (2022). While both Commentaries acknowledge that my therapy with Jane was ultimately quite helpful to her, both point to the turbulent and conflictual nature of a substantial portion of our therapeutic relationship. Galen et al. attribute this struggle in part to the DBT equivalent of "countertransference" dynamics in my therapeutic relationship with Jane; and Ruork attributes this struggle in part to my under use of the DBT concept of "secondary targets." I found both of these perspectives very on target, and they stimulated me to reconstruct a crucial theme in the therapy from excerpts of therapy process in sessions 14-24 of my case study of Jane. I end the article by reflecting on the value of writing up systematic case studies with sufficient descriptive clinical detail so that valuable secondary analyses can be conducted, like those by Galen et al., by Ruork, and by me based on the former two.
Parts of the Self, Schema Modes, Alters, and Narrative and Pre-Narrative Selves: Understanding and Working With Multiplicity
Authors: Edwards David J.A.
Published: June 2023

The account of Kelly's therapy (Edwards, 2022b), and the commentaries by Singer (2022) and Margolin (2022), each, in different ways, highlight the significance of multiplicity, and the importance of understanding it, for the practice of psychotherapy. For several decades, many approaches to therapy have recognized and provided guidelines working with this multiplicity (Hermans & DiMaggio, 2004; Kellogg & Young, 2006; Lazarus & Rafaeli, in press; Rowan & Cooper, 1999; Schwartz, 1997; Stiles, 2011; Teasdale, 1999; Watkins & Johnson, 1982). Schema therapy is an integrative therapy that draws freely on these historical traditions, while offering its own distinctive framework for using multiplicity in case conceptualization for a wide variety of clinical phenomena (Edwards, 2022a).  Examination of processes within cases treated within this framework provides the opportunity to further develop and synthesise clinically grounded theory, and, as Edwards (2022b) argued, it is increasingly possible for that practice to be grounded in a scientific understanding of the systems of memory and learning that underlie the client’s experience, drawing on the significant advances in our understanding of autobiographical memory systems. This article continues to explore this idea by responding to the commentaries on the case study of Kelly by Singer and Margolin.
Maximizing Exposure's Benefit: Making it Possible, Bearable and Fruitful
Authors: Skean Karen
Published: June 2023

Exposure is hypothesized to be a key active ingredient in several approaches to psychotherapy. Dr. Irada Yunusova (2023) explores this as a common element in both Accelerated Experiential Dynamic Psychotherapy (AEDP) and behavioral exposure therapy. The current commentary elaborates on other important factors that contribute to maximizing the effectiveness of interventions in both these models. These include titrating the level of challenge, memory consolidation, common factors, and neuroplasticity. Dr. Yunusova’s detailed case review is an example of assimilative integration, where one can see her incorporation of a model new to her (AEDP) into her home base of Behavior Therapy, as well as the factors noted above that enhance its effectiveness.
Additional Perspectives on the Case of "Chris"
Authors: Yunusova Irada
Published: June 2023

In this article, I respond to commentaries by Dr. Karen Skean (2023) and by Dr. Lauren Lipner (2023) on my case study of "Chris" (Yunusova, 2023), a 30-year-old man who presented to treatment with presenting problems related to depression and aspects of complex PTSD. First, I discuss the way in which Skean precisely captures the core processes in my therapy with Chris. This includes (a) how my use of Fosha's AEDP, which emphasizes the development of a close, warm, and open moment-to-moment relationship between therapist and client, incorporated the behavioral concept of exposure; (b) how this use of exposure must be tailored to the individual client in line with Vygotsky's "Zone of Proximal Development"; and (c) the role of memory reconsolidation in helping to revise traumatic memories. I also discuss the deep positive impact of the case of Chris, as supervised by Dr. Skean, on my subsequent development as a therapist. Second, I discuss how valuable I found Dr. Lipner's viewing of my description of the clinical process of therapy with Chris through a theoretical lens quite different from the one I used, including (a) Goldfried's "principles of change," and (b) Safran and Muran's model for identifying and repairing "ruptures in the therapeutic alliance."  Finally, I also respond to Dr. Lipner's question about the way in which I handled the exchange of letters with Chris at the end of our therapy.
Pravni tretman insajderskih informacija prema novom zakonu o tržištu kapitala
Authors: Vranić Marija
Published: June 2023

The legal treatment of insider information must be carefully and precisely determined, given the considerable number of specifcs that accompany insider information and the multiple legal and economic consequences of its misuse. To the one who possesses it, insider information provides a signifcant advantage in terms of the disposal of the fnancial instruments to which it relates, in relation to investors in the same instruments to whom they are unknown. Since the advantage is based on an unjustifed information asymmetry, insider trading is an unfair market action, which requires a strong legal response in the form of a ban and adequate sanctions in case of ignoring it. The new Law on the Capital Market, the implementation of which has begun on January 6, 2023, brings certain changes in the legal treatment of insider information. Although the essence of the regulation of this institute remains the same, there is a noticeable harmonization of the regulations in this area with the regulations that exist within the framework of European Union law. The aim of this work is to analyze the current solutions, especially pointing out the introduced changes. The application of the comparative law method also contributes to the research results.
Provisions Regarding Low Heritage In The Compilation Of Islamic Law (Study In Nagari Koto Gadang, Koto Besar District Dharmasraya District)
Authors: Putri Delfia Eka , Jaewon Cizmeci , Simone Smallridge
Published: June 2023

The purpose of this research is to explain the distribution of low inheritance that occurs in Nagari Koto Gadang. The research method used in this study is a qualitative method, in which data collection uses interview techniques from the Nagari Koto Gadang community. In Minangkabau custom, there are two types of inheritance that are inherited, namely high inheritance and low inheritance. Low inheritance assets are assets originating from one family's livelihood assets, in the form of rice fields, fields purchased from other parties. In this study it can be concluded thatThis low inheritance can be inherited through customary law and Islamic law. Because there is a similarity, that is, low inheritance is an inheritance in Minangkabau custom, and low inheritance can be donated according to Islamic law.
Distribuição geográfica potencial do araticum (Annona crassiflora)
Authors: Martins Patrick Thomaz de Aquino
Published: June 2023

O araticum (Annona crassiflora Mart.) é uma planta nativa do Cerrado que possui importância social, cultural e econômica devido aos diversos usos que pode ser empregado. O contexto em que esta espécie se encontra, com fatores que reduzem o seu habitat e limitam sua reprodução, legitima a identificação das áreas potenciais de sua ocorrência, o que pode auxiliar no gerenciamento e restauração do seu habitat. Neste sentido, o presente trabalho teve como objetivo analisar a distribuição geográfica potencial do araticum. Com base em pontos de ocorrência e em dados ambientais (climáticos e edáficos), foram gerados seis modelos de distribuição geográfica potencial do araticum e um mapa de consenso destes modelos (ensemble). Este último foi objeto de análise também quanto à intersecção espacial com o uso e cobertura da terra e com Unidades de Conservação (UC). Os seis modelos foram satisfatoriamente ajustados e, juntamente com o ensemble, sugerem uma zona contígua que compreende aproximadamente 22,37% da região neotropical como adequada à ocorrência do araticum e tem seus maiores valores de adequabilidade ambiental distribuídos majoritariamente no território brasileiro. A área de distribuição potencial do araticum no Brasil apresenta forte presença antrópica e baixa presença de UC, sobretudo as pertencentes ao grupo de proteção integral, sendo necessário um conjunto de ações e planos que possam garantir a sua preservação.
Teknoloji Kabul Modeli Bağlamında Öğrencilerin Davranışsal Niyetine Etki Eden Etmenlerin Belirlenmesi
Authors: ÇELİK Sabri , TÜRKOĞLU Turgut , BAYDENİZ Erdem , SANDIKCI Mustafa
Published: June 2023

Bu çalışmanın amacı Teknoloji Kabul Modeli (TKM) bağlamında davranışsal niyete etki eden etmenlerin belirlenmesidir. Araştırmanın evrenini Afyon Kocatepe Üniversitesi Turizm Fakültesi öğrencileri oluşturmakta olup veriler kolayda örneklem metodu ile anket formu kullanarak 01-30 Mayıs 2022 tarihleri arasında yüz yüze ve çevrimiçi ortamlarda toplanmıştır. Veriler Warp PLS istatistik programında analiz edilmiş ve verilerin çözümlenmesinde betimsel istatistiklerin yanı sıra yapısal eşitlik modellemesinden faydalanılmıştır. Araştırma sonuçlarına göre kullanışlılık, kolaylık ve değerin tutum üzerinde pozitif yönlü anlamlı bir etkisi olduğu, hedonik motivasyonun ise tutum üzerinde anlamlı bir etkisinin olmadığı belirlenmiştir. Ayrıca tutumun davranışsal niyet üzerinde pozitif yönlü anlamlı bir etkisinin olduğu tespit edilmiştir. Araştırma sonuçları neticesinde öneriler geliştirilmiştir.
Mediation proceedings following the amendments made by the Act of 2 December 2021 amending the Act Civil Code, Act Code of Civil Procedure and certain other acts in the context of the provisions of Art. 8(1) of Directive 2008/52/EC of the European Parliament and of the Council of 21 May 2008 on certain aspects of mediation in civil and commercial matters.
Authors: Grajewska Kamila , Grajewski Artur
Published: June 2023

The article describes mediation in civil proceedings. It also presents legislative solutions introduced by the Act of 2 December 2021 amending the Act Civil Code, Act Code of Civil Procedure and some other acts (Journal of Laws, item 2459), aimed at re-regulating the effects of initiating mediation proceedings for the limitation period. In summary, it contains an assessment of the changes introduced, also in the context of the provisions of the EU directives on mediation and other forms of out-of-court dispute resolution, in particular with the participation of consumers, regarding the issue of the course of the limitation period.
Optimización de procesos en la gestión pública ecuatoriana
Authors: Quintero-Cuero Gustavo Ricardo
Published: June 2023

La optimización de los procesos de gestión pública es un tema de suma vigencia y relevancia para todas las naciones del mundo de cara al cumplimiento de los objetivos de desarrollo sostenible 16 y 17 de la Agenda 2030 de la ONU.  Los citados objetivos están vinculados a la construcción de instituciones sólidas con responsabilidad y eficacia en todos los niveles de gobiernos, como garantía de paz, justicia e inclusión. Las instituciones necesitadas para la óptima gestión pública deben estar orientadas de forma clara a adoptar medidas urgentes que fomenten la movilización, reorientación y aprovechamiento de los recursos privados a través de alianzas entre los gobiernos, el sector privado y la sociedad civil, basadas en principios y valores, con una visión compartida y objetivos comunes, que otorgan prioridad a las personas y al planeta en todos los niveles. La metodología empleada es la revisión documental y bibliográfica de tipo descriptiva, el análisis se sustenta en la normativa vigente y estudios afines al objeto de estudio realizados por diversos autores e indexados en reconocidas bases de datos. Ecuador se encuentra inmerso en el proceso de impulsar transformaciones e innovaciones en la gestión pública que respondan a sus compromisos internacionales y sean coherentes con el paradigma del Sumak Kawsay (Buen Vivir) como forma de vida del pueblo ecuatoriano adoptado por la Constitución de la República. Para ello ha encaminado acciones que alinean la administración pública nacional con las tendencias internacionales de optimización tanto a nivel estratégico como organizativo de la nueva gestión pública.
Union of the Romanian Principalities and the Collective Guarantee of the European Powers
Authors: CLIVETI Gheorghe
Published: June 2023

This study reveals a very specific issue in the field of the international relations history. As a matter of fact, the Romanian State՚s emergency presupposed an international regime exposed through the joint guarantee of the European Great Powers, as signing parts of the Peace Treaty of Paris, from the 30s March 1856. The readings of that Treaty and of the many other papers proved the fact that the Guaranteeing Powers were the six European Great Powers, as France, Great Britain, Austria, Prussia, Russia, and Sardaigne. The Ottoman Empire, as suzeraine Court on the Romanian Principalities Moldavia and Wallachia, as well on Serbia, it was a guaranteed, and not a guaranteeing part. These revealings permitted some pointed understandings of the both international impact of the Romanian international acts, as, for example, the Union of the Principalities in 1859, and significations of the diplomatic European deliberations, as the Great Powers Concert on the Romanian Question.
The Union of the Principalities with Foreign Prince From Strategy of Diplomacy to Romanian National Project
Authors: PLOSCARU Cristian
Published: June 2023

"In Romanian hisoriography, the beginnings of the modern idea of political unity, of the national state, are placed in the years of the rule of the native princes (1822-1828) and of the Russian occupation, when the first modern manifestations in this sense appeared, concerning the union of the Wallachia with Moldavia, as a Romanian state, a buffer state between Russia and the Ottoman Empire, based on the historical rights in relation with the Porte, a state with modern institutions, according to the understanding and interests of the elite of the time. An interesting conclusion, resulting from a contextual analysis of the transformations of the period, without benefiting from too many explicit documentary references. Nevertheless, previous proposals concerning the establishment of a principality or kingdom of Dacia have been intensively discussed by Romanian and foreign historians, but, in our opinion, insufficient clarification has been provided regarding the extent to which these proposals belong or not to the history of the modern Romanian national project. In order to be able to make some reasoned conclusions we propose to conduct a comparative study. On the one hand, the ""Dacia project"" promoted by Russia in the years following the Treaty of Kuciuk Kainardji and the Ainalî Kavak Convention, subsequently associated with some Russian plans for the reorganization of the Balkans promoted especially by Ioannis Kapodistrias, deserves special attention. On the other hand, after 1821, in a historical context influenced by the outbreak of the Greek revolution and the efforts of the Great Powers to find solutions for the organisation of a Greek Christian principality, the first Romanian proposals for the Union of Moldavia with Wallachia into a national state were to appear, the most important being the proposal of January-February 1830 to achieve the union with a foreign prince, in the person of Gustav of Vasa, former Crown Prince of Sweden."
A Fighter for the Union of the Principalities: Anastasie Panu
Authors: COJOCARIU M.
Published: June 2023

"Between 20 October 1858 and 5 January 1859 (according to the old calendar), Anastasie Panu was a member of the Three-Kaymakam rule, installed in Moldova under a provision of the Paris Convention on the definitive organization of the Romanian Principalities. He was, in that capacity and for that 77-day period, the most important Unionist politician, with a decisive role in the ""course"" of the Moldavian events that preceded the election of Alexandru I. Cuza as ruler. It is to him that we owe, to an overwhelming extent, the restoration of the freedom of the press (by reinstating Grigorie Al. Ghica's law of May 1856), the full affirmation of the country's autonomy through an effective exercise, ensuring a (relative) majority of the National Party in the Elective Assembly of Moldavia, the introduction of the letterhead of the United Principalities on all official documents; finally, through the so-called ""Panu Plan"", ""paving"" the road to the throne of Moldavia for Colonel Alexandru I. Cuza. Therefore, this Unionist leader should be given not only our modest presentation, but a monument more enduring than bronze - if we may paraphrase the ancient poet: and not (almost) the oblivion bequeathed by an unjust posterity."
HABITAÇÕES DE INTERESSE SOCIAL COMO POLÍTICAS PÚBLICAS: UMA REVISÃO SOBRE AVALIAÇÃO PÓS OCUPAÇÃO
Authors: Sales Laina Priscila de Oliveira , Michels Caren
Published: June 2023

A habitação influencia sob diferentes aspectos a qualidade do morar, além de proporcionar segurança, bem-estar e proteção. A moradia faz parte de um conjunto de fatores urbanos, sociopolíticos, econômicos, culturais e projetuais que ao serem negligenciados podem afetar negativamente a vida do usuário a longo prazo. O objetivo deste estudo consiste em identificar as métricas de usabilidade utilizadas na avaliação pós ocupação em habitações de interesse social para a investigação do ambiente construído. Para tanto, foi desenvolvida uma revisão bibliográfica da literatura por meio de protocolos de buscas especificas, com base na questão de pesquisa: “Quais são as métricas de eficiência, eficácia e satisfação para estudos de Avaliação Pós Ocupação em habitações de interesse social”. Como resultado, foi possível selecionar algumas pesquisas e identificar as principais abordagens técnicas e metodológicas que têm sido utilizadas em estudos de casos na investigação do ambiente construído por meio da avaliação pós ocupação.