bluuebunny/crossref_metadata_2025 huggingface dataset:
An Ecosystem Approach to Human Resource Management
Authors: Aktepe Şafak Öz , Tan Başak Uçanok , Işık İdil , İslamoğlu Güler , Birsel Melek , Yücel Betül
Published: July 2022

Amid the COVID-19 pandemic, both practitioners and academics faced surmountable issues that created a massive toll on both organizations and employees. The new complexities surrounding organizations call for novel approaches in understanding the future of work and its components. HR carries a critical strategic function for organizations to adapt to the various complexities and develop strategies that enable them to manage people when uncertainty prevails. The “ecosystem” emerged as a concept that drove theoretical and HR strategy discussions in the last two decades. Its advancement reflects a growing interest regarding the interdependence in elements, structures, and actors across organizations and activities. The COVID-19 pandemic highlights the critical importance of interconnectedness for surviving in today's highly volatile environment. Thus, this work proposes a preliminary theoretical model of the HR ecosystem in the COVID-19 context using the arguments of systems and complexity theories and the current HR literature.
Do Commercial Banks Benefit From Bank-FinTech Strategic Collaboration?
Authors: Fang Ying , Ye Li , Wen Guo-Feng , Wang Rong
Published: July 2022

The banking sector has changed fundamentally as digital transformation is enabling new technology-driven banking business and creating novel customer requirements. Embracing bank-FinTech strategic collaboration (FSC) has been particularly vital to digital transformation of Chinese city commercial bank. The aim of this paper is to study the impact of FSC on the efficiency of city commercial banks. Using data from Chinese city commercial banks between 2014 and 2019, we first measure bank efficiency scores using stochastic frontier approach. Moreover, we employ the propensity score matching approach and the difference in difference estimation to explore the effect of FSC on bank efficiency. We find that FSC significantly improves bank cost and interest revenue efficiency in the aggregate. Our results also indicate that the positive relationship between FSC and cost efficiency is negatively associated with bank ownership concentration. In addition, the positive effects of FSC on revenue efficiency are weaker in state-owned city banks than in non-state-owned city banks.
Hybrid Air Route Network Simulation Based on Improved RW-Bucket Algorithm
Authors: Xin Lai , Cun Zhao De , Yang Huang Long , Ti Wu D.
Published: July 2022

The fixed-route network is the basis for airlines to carry out flight direction planning. Some countries and regions have introduced temporary routes as a supplement to the fixed route structure. Temporary routes have the advantages of intercepting curves and straightening, and less detouring areas, which can save airlines fuel consumption and improve operational efficiency. This article takes the mixed airline's route network as the research object. Firstly, the structural properties of mixed air route networks are analyzed by using complex network theory. Secondly, the RW-bucket algorithm to generate a mixed air route network structure is analyzed. According to the conclusion of the analysis, the RW-bucket algorithm is improved. Finally two flight information region route network data are used to verify the proposed hybrid route network construction method by computer simulation.
Flight Control Technology Advancements and Challenges for Future Rotorcraft 40th Alexander A. Nikolsky Honorary Lecture
Authors: Tischler Mark B.
Published: July 2022

The goal of my 40th Alexander A. Nikolsky Honorary Lecture and journal paper is to highlight the key flight control technology advances of the past 50 years and demonstrate how these advances are being applied and extended to the new family of rotorcraft: modern high-speed military
rotorcraft, eVTOL urban air mobility, and advanced air mobility aircraft. The first part of this journal paper reviews flight control technologies drivers that are unique to rotorcraft and highlights key advances of the past 50 years in the areas of handling-qualities requirements (ADS-33),
physics-based models, system identification, and flight control. A central theme is the shift from time-domain to frequency-domain based characterization of the closed-loop response and design methods for rotorcraft that have become increasingly dependent on sophisticated feedback control
systems to achieve closed-loop stability, disturbance rejection, and most importantly closed-loop handlingqualities response for all-weather operations. Frequency-domain analysis, design, and test methods of the past 50 years are highlighted relating key advances in each discipline and two
integrated example success stories. In the second part of this paper, we consider the key challenges, advancements, and needed future research for four new classes of rotorcraft: the military future vertical lift family of high-speed rotorcraft, unmanned autonomous systems/urban air mobility
based on fielded conventional helicopters, small electric VTOL unmanned aerial vehicle rotorcraft, and larger eVTOL urban air mobility rotorcraft. The next sections look across the challenges and solution spaces that are common to these four new classes of rotorcraft as a blueprint for needed
research advances. Finally, this paper takes a step back and considers the lessons-learned and key takeaways from the author's perspective as a career-long flight control engineer/researcher, Flight Control Technology Group leader, and senior technologist.
An in-vivo study on postprandial hyperglycemia to assess antidiabetic activity of alcoholic extract of Cinnamomum verum bark
Authors: Nayan Md. Iqbal Hossain , Alam Md. Mohibul , Jamil Md. Abrar , Hannan J.M.A. , Haq Iqramul , Hossain Md. Ismail
Published: July 2022

Background and objective

Cinnamomum verum bark is locally known as ‘Daruchini’ and is traditionally reputed as an Ayurvedic medicine, which is used in the treatment of flatulence, toothache, heart diseases, fever, cough, cold, headache, and many others. In this study, we intended to explore the effectiveness of its activity on hyperglycemia.

Materials and methods

To evaluate its antihyperglycemic activity, we used various experimental designs, including the effect of plant extract on gastrointestinal (GI) motility in the Swiss albino mice model and intestinal disaccharidase enzyme activity and carbohydrate digestion and absorption in the gut of the Long Evans rats.

Results and discussion

The plant extract significantly (P<0.001) increased the GI motility rate by ∼16% than the control (distilled water, 10 ml/kg body weight) and indicated that it interfered with the rate of glucose absorption in the gut. Furthermore, treatment with C. verum caused a significant (P<0.05) dose-dependent reduction of intestinal disaccharidase enzyme activity from 1.63 to 1.21 µmol/mg protein/h in fasting Long Evans rats. Besides, the extract produced a similar effect in the acute oral sucrose (2.5 g/kg body weight) load assay, in which a substantial amount of unabsorbed sucrose was found in six different parts of the GI tract after sucrose administration. This indicates that C. verum can liberate GI content and reduce or delay glucose absorption.

Conclusion

All the findings of the present study point to the conclusion that C. verum has the potential to exert postprandial antihyperglycemic activity within type 2 diabetic animal models through reducing or delaying carbohydrate digestion and absorption in the gut.
Evaluation of fresh water lactic acid bacteria for production of optically pure L-(+)-lactic acid
Authors: Elkhateeb Waill A. , Hamdan Amira M. , Zendo Takeshi , Ishibashi Naoki , Daba Ghoson M. , Tashiro Yukihiro , Sonomoto Kenji
Published: July 2022

Background and objective

Lactic acid bacteria (LAB) are generous producers of many industrially important products. Of these products, optically pure lactic acid is of great value as it is essential for production of highly crystalline poly-lactic acid, which is the most widely used biodegradable synthetic polymer. Hence, this study aimed to screen for thermotolerant LAB from a new source, which is fresh water samples collected from the coast of the Nile River, Egypt, and then evaluate their ability to produce optically pure L-lactic acid.

Materials and methods

LAB strains were isolated at 50°C and evaluated for producing optically pure L-lactic acid using high-performance liquid chromatography and BF-5. Effects of medium containing different sugar sources, incubation temperature, and initial pH of the medium on the purity and productivity of L-lactic acid were also studied.

Results and discussion

All obtained isolates were capable of producing optically pure L-lactic acid on different sugar sources. Changing the incubation temperature to 30°C positively affected both productivity and optical purity, which reached 5.0 g/l of 100% optically pure L-lactic acid. On the contrary, pH of the medium was confirmed to be also one of the major factors affecting productivity and optical purity of obtained L-lactic acid. For our isolates, pH 7.0 was the optimum one for the production process. The four promising producers of 100% optically pure L-lactic acid were molecularly identified as Lactiplantibacillus sp.

Conclusion

This is the first study describing the evaluation of the ability of fresh water LAB isolated from the Nile River to produce optically pure L-lactic acid.
Reliability of analgesia nociception index (ANI) and surgical pleth index (SPI) during episodes of bleeding – A pilot study
Authors: Muthukalai Sindhupriya , Bansal Sonia , Chakrabarti Dhritiman , Rao GS Umamaheswara
Published: July 2022

Background and Aims:

Analgesia Nociception Index (ANI) and Surgical Pleth Index (SPI) are measures of nociception-antinociception balance during general anaesthesia. The validity of these two monitors during autonomic changes brought about by intraoperative blood loss and noradrenaline infusion has not been studied earlier. The primary objective of the study was to determine the effect of bleeding on ANI and SPI. The secondary objective was to observe the effect of noradrenaline infusion on ANI and SPI and the correlation between ANI and SPI.

Methods:

In this prospective observational study, 43 patients undergoing surgery for excision of a meningioma or for traumatic brain injury were included. Heart rate, mean arterial pressure, ANI, SPI, response and state entropy were recorded every 5 min from anaesthetic induction till skin closure. ANI and SPI values before bleeding were compared with the values following bleeding. The effect of bleeding and noradrenaline on ANI and SPI were studied using linear mixed effect model.

Results:

Bleeding increased the values of ANI and the increase was higher in the presence of noradrenaline and it was statistically significant (P = 0.028 and 0.023). SPI was not affected by bleeding or with noradrenaline infusion. ANI and SPI had a poor negative correlation (r = - 0.01).

Conclusion:

Values of ANI increased significantly during episodes of intraoperative acute blood loss and with co-administration of noradrenaline. SPI seems to be more dependable when compared to ANI under such conditions.
Ropivacaine instillation through subgaleal drain: A novel approach for acute post-craniotomy pain
Authors: Bala Renu , Gehlaut Preeti , Mittal Kiran , Singh Ishwar
Published: July 2022

Background and Aims:

Post-craniotomy pain has often been overlooked and undertreated. Various classes of analgesic drugs have been used, not without limitations. Therefore, we planned to study the novel technique of wound instillation of ropivacaine through the surgical drain in patients undergoing supratentorial craniotomy to study its effect on post-craniotomy pain, analgesic requirement in the post-operative period along with the recovery profile of the patient and the side effects.

Methods:

This prospective, randomised, placebo-controlled, double-blinded study enroled 50 patients of either gender, scheduled to undergo elective craniotomy, under general anaesthesia. They were randomly divided into two groups and received either 12 ml of 0.25% ropivacaine (group R) or 12 ml of normal saline (group NS), through the subgaleal drain, after the closure of the dura. Pain scores were assessed at 1, 2, 4, 8 and 24 hours post-operatively. Student’s t-test was used for comparison of continuous variables and the Chi-square test or Fisher’s exact test was used for comparing the nominal categorical data.

Results:

The visual analogue scale score was higher in group NS than in group R, and the difference was statistically significant (P = 0.012, 0.016, and 0.005 at 0, 1, and 2 post-operative hours, respectively). The difference in the mean emergence time in the two groups was 1.12 minutes (P = 0.024).

Conclusion:

Single-time wound instillation of ropivacaine (12 ml of 0.25%) through surgical (subgaleal) drain during wound closure is an effective and simple technique for reducing post-operative pain and analgesic consumption and early emergence in neurosurgical patients undergoing supratentorial craniotomy.
Analysis of clinical presentation, biochemical profile, and management of liver abscess in North India
Authors: Angelin Powlina A. , Gupta Shalabh , Bhagat Tripta S. , Goel Apoorv , Sagar
Published: July 2022

Objectives:

Liver abscess is a common disease in tropics with high morbidity and mortality if left untreated. It is quite prevalent among low socioeconomic population. In this study, we have analyzed the clinical and biochemical profile with management options for cases of liver abscess presented at a tertiary care hospital of Northern India.

Materials and Methods:

This was an observational prospective study conducted at Santosh Medical College and Hospital from March 2019 to March 2021. All patients underwent extensive clinical, biochemical evaluation and radiological examination, followed by treatment as per reports and requirement. All results were formulated in tabular form and analyzed accordingly.

Results:

Liver abscess is commonly seen in the Indian subcontinent. Middle-aged males are predominantly affected. Alcohol intake and diabetes are the significant risk factors. Pain abdomen and fever were the most frequent complaints. Escherichia coli was the most common organism causing pyogenic liver abscess. More than 75% of the cases can be treated with antibiotics and ultrasound-guided single needle aspiration.

Conclusion:

Hepatic abscess is a common disease of Indian subcontinent. Early diagnosis and treatment is essential to prevent mortality. Ultrasound has emerged as a cheaper and effective diagnostic modality. The incidence of tubercular hepatic abscess is not uncommon.
Intralesional bleomycin for the management of recalcitrant periungual warts
Authors: Garbyal Priyal Rhenjen , Garg Vijay Kumar , Karira Sheraun , Yadav Garima
Published: July 2022

Ungual warts are very common benign growths in the dermatological outpatient department that are often tough to treat as they are resistant to available treatments and frequently recur. A variety of therapeutic modalities have been used with varying degrees of success. Intralesional bleomycin has emerged as an effective treatment option for recalcitrant periungual warts with minimal side effects. We report the case of a 22-year-old male with recalcitrant ungual warts which responded dramatically to intralesional bleomycin.
Difference in the cognitive profile of children with specific learning disabilities
Authors: Mathew Varghese , Srivastava Rani , Nair Anil Kumar
Published: July 2022

Context:

Specific learning disabilities (SLDs) is a neurodevelopment disorder characterized by normal intelligence, and marked difficulty in academics and scholastic performance, thereby expressing gross discrepancy in the ability and achievement. Children with SLD have a typical cognitive profile. Like among the normal children, variance in the distribution of the intelligence is also observed among the children with SLD.

Aims:

The present study intends to categorize the children with SLD based on the intelligence quotient (IQ) and compare it with the nonlearning disabled (NLD) and further explore the cognitive profile associated with the respective category of SLD children.

Settings and Design:

In the present study, three groups of children in the age range of 8 to 12 years studying in 3 to 7th standard were selected as the sample for the study.

Subjects and Methods:

Seventy-seven children with SLD and 24 NLD children were tested for their IQ using the Wechsler's Intelligence Scale for children-IV. Seventy-seven children with SLD were categorized into two groups based on their Full-Scale IQ (FSIQ). The results were statistically analyzed and compared.

Statistical Analysis:

Independent sample t-test was used for the statistical analysis.

Results:

It was found that 58.4% of children with SLD had the FSIQ below 90 and 41.6% of children with SLD represented with the FSIQ as above 90. Both the groups of SLD children were compared with the NLD group. The significant difference is observed in the cognitive proficiency index (CPI) and general ability index (GAI). The SLD children of FSIQ below 90 had deficits in the domain of CPI and GAI and the SLD children with FSIQ above 90 had deficits in the area of CPI alone. The GAI and CPI of these children were further analyzed to reveal that the SLD children with FSIQ above 90 had difficulty in the area of working memory.

Conclusion:

The SLD may be represented as two different categories based on the cognitive profile. One category of children with SLD has their problems and difficulties confined to the domain of the working memory, while the other category of children has difficulty in the area of both GAI and CPI indicating difficulty in perceptual reasoning, working memory, and processing speed.
Evaluation of colposcopy in screening of suspicious-looking cervix using swede score and its correlation with the histopathological findings
Authors: Agarwal Neelima , Gupta Manisha , Agrawal Alpana , Tekta Karisma
Published: July 2022

Background:

Cervical cancer is a global health problem. It ranks as the fourth-most common leading cause of female cancer in the world and the second leading cause of female cancer in India. Different methods are used for its screening as it has a long latent phase. Colposcopy-guided biopsy of suspicious unhealthy-looking areas is taken as the gold standard in the diagnosis of intraepithelial lesions. However, a new scoring system of colposcopy called the Swede score has a high specificity and can omit the need of biopsy.

Objective:

The objective of this study is to evaluate the diagnostic efficacy of colposcopy using Swede score in unhealthy cervix and to determine the degree of correlation between colposcopy scores and histopathological findings.

Materials and Methods:

The study was conducted in the Department of Obstetrics and Gynecology, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh, India, from January 1, 2020, to June 30, 2021. Ninety-eight patients fulfilling the inclusion and exclusion criteria were selected for the study.

Results:

It was evident that colposcopy using a Swede score of >5 and even more of >7 is definitely more sensitive and accurate in the screening of unhealthy-looking suspicious cervix in the Indian population and can be considered to use for performing a direct excisional procedure or cryotherapy as a “see and treat” method at this cutoff point, avoiding the need for cervical biopsy for histopathological confirmation.

Conclusion:

Swede score performed well in this hospital-based study on a selected population coming to gynecology OPD with complaints of lower abdominal pain, discharge per vaginum, dyspareunia, abnormal uterine etc. referred to the colposcopy clinic in view of unhealthy- looking suspicious cervix.
Precision medicine in COVID-19 patients
Authors: Tomo Sojit , Batra Jyoti , Aggarwal Juhi
Published: July 2022

The coronavirus disease (COVID-19) pandemic has emerged as one of the deadliest pandemics that humanity has ever seen, affecting almost all countries in the world. The pandemic has taken a severe toll on the almost all realms of the society. The management of the pandemic is further complicated by the emergence of various strains of virus and differing phenotypes of severity in a population. The complex interplay between underlying host factors and evolution of viral strains makes it a daunting task to standardize the treatment protocols across a population. In this context, it is imperative to look into the solutions that the precision medicine may provide us for categorizing patient population, in tailoring treatment and in identifying newer treatment targets. In this review, we discuss the possibilities that precision medicine put forward in tackling COVID-19 pandemic.
Association of CD4 cell count and antiretroviral therapy antibody production in Human Immunodeficiency virus seropositive subjects on antiretroviral drugs in Benin City, Nigeria.
Authors: Obazelu Progress Arhenrhen , Emokpae Mathias Abiodun
Published: July 2022

Antiretroviral therapy (ART) is widely used and subjects on ART were reported to develop antibodies against these drugs when used as monotherapy. The aim of this study was to determine the proportion of HIV-sero positive subjects on antiretroviral therapy who developed antibodies to the drugs used as combination therapy and to associate the presence of antibodies to CD4 cell count which is a marker of disease progression. A total of 300 subjects were randomly selected for the study, consisting of 100 HIV-sero positive subjects already on ART, 100 newly diagnosed HIV-sero positive ART- naive subjects and 100 HIV-sero negative individuals who were monitored as controls. CD4 cell count and complete blood count were assayed using BD FASCOUNT CD3/CD4 and Sysmex KX-21N autoanalyzer respectively. Antigen-Antibody agglutination technique was used to detect antibodies produced against antiretroviral drugs in HIV -sero positive subjects on ART. The results showed that antibodies to antiretroviral drugs (tenofovir disoproxil fumarate/lamivudine Efavirenz + lamivudine/ nevirapine/zidovudine combination) were detected in 33(33%) out of the 100 HIV-sero positive subjects on ART studied. Significantly higher CD4 cell count (p<0.001), PCV (p<0.001) and white blood cell count (p<0.001) were recorded among control group than HIV positive subjects whether they in 33(33%) out of the 100 HIV- sero positive subjects on ART combination studied.  The use of combination therapy has led to a smaller number of subjects on ART who developed antibody as against a higher percentage on monotherapy that was previously reported. Significantly lower level of platelet was observed among HIV-sero positive subjects who developed ART antibodies.
Confinamiento y Salud Mental de Niños, Niñas y Adolescentes
Authors: Solis Campos Inés Julissa
Published: July 2022

La salud es necesaria para el bienestar de toda persona. Pero cuando hablamos de salud lo primero en lo que pensamos es en la salud física, no en la salud mental. A finales del 2019 el mundo fue afectado por el Virus SARS- CoV- 2 sin imaginar las consecuencias que esto traería no solo a nivel físico sino a nivel social, ambiental y mental. El encierro, la enfermedad, el duelo ha tenido un impacto directo en la salud mental de las personas en las diferentes etapas de la vida.
Energía Neta Cero en Edificios
Authors: Ramos Chacón Santos Javier
Published: July 2022

Los edificios en su gran mayoría utilizan mucha energía hoy en día, para mantener las luces encendidas, calentar el agua, enfriar el aire, y alimentar los dispositivos personales, como laptops, computadoras, celulares, y demás artefactos eléctricos.

Incluso la instalación de sistemas solares no contrarrestará significativamente la gran cantidad de energía, sin embargo, hay edificios que logran un equilibrio e incluso inclinar la balanza al otro lado, estos serían los llamados edificios de energía neta cero.
The Effects of GA3 and Storage Time on the Germination of Epigaea gaultherioides (Ericaceae) Seeds
Authors: Pulatkan Müberra , Çimen Nebahat , Kurt Uğur , Turna İbrahim
Published: July 2022

Turkey is a country with diverse plant species and has significant potential in landscape planning. Epigaea gaultherioides (Boisse et Bal.) Takht. is a relic of the Black Sea (Euxine) province, aesthetic, and functional species indigenous to Northeastern Turkey and under the threat of extinction. The species should be cultured to ensure the permanence of the species with ex situ methods and employed in landscape planting design. The present study aimed to determine the effects of gibberellic acid (GA3) and cold storage time on seed germination performance in E. gaultherioides. Cold storage was applied to the seeds at +4 ºC for 16 and 28 months and subsequently the seeds were soaked in GA3 (0, 100, 500 and 1,000 ppm) solutions for 24 hours. The findings indicated that E. gaultherioides seeds that were not treated with GA3 solutions did not germinate. However, it was determined that germination was low in seeds treated with 500 ppm GA3, and 80% of the seeds germinated when treated with cold storage at 25 °C (24 h dark) for 16 months. The ANOVA revealed that there were statistically significant differences between germination percentage and mean germination times for various gibberellic acid doses and cold storage – time processes.  Keywords: cold storage time, germination rate, gibberellic acid, landscape, relict
Quality of life of children with mucopolysaccharidoses on the background of enzyme replacement therapy
Authors: Osipova Liliya A. , Kuzenkova Ludmila M. , Chernikov Vladislav V. , Podkletnova Tatyana V.
Published: July 2022

Introduction. Mucopolysaccharidoses (MPSs) represent a group of rare lysosomal storage diseases, associated with the decline in life expectancy and impairing it’s quality. Despite prolonged evaluation of the effectiveness of pathogenic therapy, patient-reported outcomes are poorly defined. The aim of the study. To describe the impact of enzyme-replacement therapy (ERT) on the quality of life in MPS children, using parent-completed validated questionnaires. Materials and methods. Parents of forty five MPSs children (27 - with neuronopathic disease, 18- with non-neuronopathic disease, 31 among them were treated with ERT) completed parent proxy-report of Pediatric Quality of Life Inventory™ (PedsQL™) 4.0 Generic Core Scales. Parents of seventeen children (10 - with neuronopathic disease), treated with ERT, completed PedsQL™ 4.0 Generic Core Scales twice, parents of 7 children with non-neuronopathic disease, treated with ERT, completed Childhood Health Assessment Questionnare (CHAQ) and visual analogue scale (VAS) of pain and overall health status, parents of 10 children with neuronopathic disease, treated with ERT, completed VAS of pain and overall health status twice. Cross-sectional and dynamic analyses have been undertaken. Results. Stabilization and lack of significant improvement of functional disability, quality of life and VAS scores of pain and overall health status have been demonstrated. In 57% of patients with non-neuronopathic disease, treated with ERT, mean score of «School Functioning» decreased, in 80% of patients with neuronopathic disease, treated with ERT, mean score of «Physical Functioning» decreased. In 50% of children with neuronopathic disease and in 57% of children with non-neuronopathic disease, mean score of «Emotional Functioning» improved. Conclusion. MPS children, treated with ERT, require additional psychological and educational help, as well as regular motor rehabilitation.
Secure Transaction System Using Face Recognition
Authors: Gupta Saksham , Tomar Sanchit , Bansal Rituraj , Choudhary Sameer , Kaur Pardeep
Published: July 2022

The use of online payment is increasing dramatically in today's environment. As a result, this initiative was created to protect payments against internet scams. The project's main goal is to create a secure payment system that uses face recognition and Open CV in Python. It makes use of the confidence level, which is defined as the value generated by the system and used to determine the forecast's accuracy. Several graphic modules were combined with a pattern mirror to create this piece. Before entering a PIN, the system in this project uses face detection and a proxy. Because it embeds elements of the users' faces to increase system accuracy, the algorithm employed in this research will improve the security and efficiency of face recognition. To strengthen security, we have introduced three-fold encryption while the data is being transmitted for authentication. The user's bank balance is confirmed and the work is completed after the system has completed its verification. The suggested system outperforms existing functions, and its user-friendly interface makes it simple to use.
OPTIMAL PROTECTION
COORDINATION OF RELAYS IN
PRESENCE OF DISTRIBUTED
GENERATION USING WHALE
ALGORITHM
Authors: Nandan S H  , Abhishek Sutar  , Subhash H Pujari  , Sayed ali  , Pasala Naresh  , SupannaS. Shirguppe
Published: July 2022

“This paperis proposes a novel nature-inspired meta-heuristic optimization algorithm, called Whale
Optimization Algorithm (WOA), which mimics the social behavior of the humpback whales. The
algorithm is inspired by the bubble-net hunting strategy”which is good comparing to others. WOA
is tested with 29 mathematical optimization problems and structural design problems. Optimization
results prove that the WOA algorithm is very competitive compared to the state the of art meta
heuristic algorithms as well as conventional methods
ОЦЕНКА СОСТОЯНИЯ ПРУДА ШЕНФЛИЗ
(Г. КАЛИНИНГРАД)
ПО ГИДРОХИМИЧЕСКИМ ПОКАЗАТЕЛЯМ В 2019 Г
Authors: Меньшенин А. С. , Цупикова Н. А.
Published: July 2022

В представленной работе рассмотрено гидрохимическое состояние одного из

искусственных водоемов г. Калининграда – пруда Шенфлиз – в 2019 г. К контролируемым

показателям качества вод относятся растворенный кислород, перманганатная окисляемость,

биогенные вещества. Выводы, приведенные в работе, основаны на данных мониторинга,

лично проводимого автором. По большинству исследованных показателей, кроме

содержания растворенного кислорода, воды пруда оценены как достаточно чистые,

олигосапробные.
Utility of Early Childhood Education Resource Rooms in Pakistani Public Schools: Analysis of Teachers’ Perspectives
Authors: Hussain Arzam , Malik Muhammad Akram , Ali Hakim
Published: July 2022

Early years of child’s life are acknowledged as vital stage for his/her all-inclusive intellectual, physical, emotional and linguistic development. Previous literature suggests that Early Childhood Education (ECE) provides solid basis for optimal development of life-long skills and consequent learning. Keeping in view the importance of ECE in international scenario, Pakistan National Education Policy (2009) made commitment to allocate additional budget for establishment of ECE resource rooms in all the public schools to provide at least one year of pre-primary education to children along with specialized training for teachers. This study, therefore, mainly focused to analyze teachers’ views about utility of ECE resource rooms in Pakistani public schools and to highlight opportunities, gaps and challenges. To achieve the objective, researchers used quantitative survey design and collected views of 308 (150 male and 158 female) randomly selected ECE teachers in district Muzaffargarh. A self-developed questionnaire comprising two factors having 45 close-ended items was used to collect data. Researchers applied both the descriptive and inferential statistical techniques to analyze the quantitative data. Overall, results suggested that majority of sample teachers showed positive perception about ECE setup as well as its utility but with some reservations. Findings further revealed that teachers' perceived utility of ECE resource rooms differed significantly in terms of their gender but not for school location. This study finally recommends that governments should increase allocation of budget to further promote ECE in public sector schools, specifically to construct purpose-build resource rooms and to train teachers.
Singapore Cancer Network (SCAN) Guidelines for Systemic Therapy of Metastatic Renal Cell Carcinoma (mRCC)
Authors:   The Singapore Cancer Network (SCAN) Genitourinary Cancer Workgroup
Published: July 2022

Introduction: The SCAN genitourinary cancer workgroup aimed to develop Singapore Cancer Network (SCAN) clinical practice guidelines for systemic therapy of metastatic renal cell carcinoma (mRCC). Materials and Methods: The workgroup utilised a modified ADAPTE process to calibrate high quality international evidence-based clinical practice guidelines to our local setting. Results: Six international guidelines were evaluated—those developed by the National Comprehensive Cancer Network (2014), the European Association for Urology (2013), the European Society of Medical Oncology (2012), the National Institute of Health and Clinical Excellence (2011), the Canadian Kidney Cancer Forum (2013) and the Asian Oncology Summit (2012). Recommendations on the first-, second- and third-line treatment for mRCC were developed. Conclusion: These adapted guidelines form the SCAN Guidelines 2015 for systemic therapy of mRCC.

Key words: Kidney cancer, Recommendations, Singapore
Dietary Protein Intake in a Multi-ethnic Asian Population of Healthy Participants and Chronic Kidney Disease Patients
Authors: Teo Boon Wee , Toh Qi Chun , Xu Hui , Yang Adonsia YT , Lin Tingxuan , Li Jialiang , Lee Evan JC
Published: July 2022

Introduction: Clinical practice guidelines recommend different levels of dietary protein intake in predialysis chronic kidney disease (CKD) patients. It is unknown how effectively these recommendations perform in a multi-ethnic Asian population, with varied cultural beliefs and diets. We assess the profile of protein intake in a multi-ethnic Asian population, comparing healthy participants and CKD patients. Materials and Methods: We analysed the 24-hour urine collections of the Asian Kidney Disease Study (AKDS) and the Singapore Kidney Function Study (SKFS) to estimate total protein intake (TPI; g/day). We calculated ideal body weight (IDW; kg): 22.99 × height2 (m). Standard statistical tests were applied where appropriate, and linear regression was used to assess associations of continuous variables with protein intake. Results: There were 232 CKD patients and 103 healthy participants with 35.5% diabetics. The mean TPI in healthy participants was 58.89 ± 18.42 and the mean TPI in CKD patients was 53.64 ± 19.39. By US National Kidney Foundation (NKF) guidelines, 29/232 (12.5%) of CKD patients with measured glomerular filtration rate (GFR) <25 (in mL/min/1.73 m2) had a TPI-IDW of <0.6 g/kg/day. By Caring for Australasians with Renal Impairment (CARI) guidelines, 76.3% (177/232) of CKD patients had TPI-IDW >0.75g/kg/day. By American Dietetic Association (ADA) guidelines, 34.7% (44/127) of CKD patients with GFR <50 had TPI-IDW between 0.6 to 0.8 g/kg/day. Only 1/6 non-diabetic CKD patients with GFR <20 had a protein intake of between 0.3 to 0.5 g/kg/day. A total of 21.9% (25/114) of diabetic CKD patients had protein intake between 0.8 to 0.9 g/kg/day. Conclusion: On average, the protein intake of most CKD patients exceeds the recommendations of guidelines. Diabetic CKD patients should aim to have higher protein intakes.

Key words: Asian continental ancestry group, Diet, Kidney failure, Malnutrition
The Effect of Servant Leadership on Employee Performance Through Burnout at PT BPJS Ketenagakerjaan Karimunjawa Branch Office
Authors: Ihza Rizaldi Rafli , Kistyanto Anang
Published: July 2022

The purpose of this study was to investigate and analyze the effect of servant leadership on employee performance through burnout on BPJS Ketenagakerjaan Kantor Cabang Surabaya Karimunjawa. Respondents to this study are as many as 34 enployee participated through a purposive non-probality sampling technique. Statistical analysis used in this study is Partial Least Square (PLS) with the help of smartPLS 3.0 software. The results showed that servant leadership has a positive and significant effect on employee performance. Servant leadership has a negative and significant effect on burnout and burnout had no significant effect on employee performance. Results also indicate thar burnout does not mediate the effect servant leadership on employee performance.
Developing Positioning For BNI as an International Bank (Focusing on Trade Finance Transactions)
Authors:   Assistant Manager, Trade Processing Center, PT Bank Negara Indonesia (Persero) Tbk, Nugroho Anissa Larasati
Published: July 2022

Following the direction from the Minister of SOEs to be an international bank, BNI revised one of its missions to strengthen international services to support the needs from our global business partner. BNI keeps making changes and improvements to be an international bank. Nevertheless, BNI is still in the second rank of the market share in international transactions. This thesis aims to develop a strong position for BNI as an international bank, focusing on trade finance transactions, as it’s the biggest contributor in terms of revenue in the international division.
Huertos escolares en la promoción de hábitos alimenticios saludables en el plato del buen comer
Authors: Santiago Flavio , Montes Rodolfo , Castillo Irma
Published: July 2022

El huerto escolar es una propuesta para la formación integral de alumnos de diferentes grados académicos y es un lugar propicio para el aprendizaje y para retomar temas sobre nutrición y alimentación; temática útil para toda la vida de un ser humano. Los conceptos abordados en el huerto escolar son una correlación entre el contenido de las materias reforzando el proceso enseñanza-aprendizaje desde la acción y la significancia de saberes. El objetivo de este documento es exponer la experiencia del establecimiento del huerto escolar en la Escuela Telesecundaria en Mexicapa, municipio de Ocuilán, Estado de México, mediante la investigación acción participativa, con alumnos, padres de familia y docentes para la promoción del plato del buen comer, adaptado a las prioridades de la comunidad. La metodología de trabajo fue cualitativa y desde un enfoque etnográfico para recuperar los resultados desde la visión de los participantes en el trabajo mediante entrevistas y un estudio de caso. Los resultados resaltan el involucramiento de los padres de familia en la gestión escolar para impulsar la formación integral del estudiante. Los huertos escolares son una buena estrategia didáctica para aprender haciendo y conseguir alimentos propios. Los estudiantes mejoran sus hábitos alimenticios, adquieren conocimientos para el cuidado del ambiente al manejar recursos e insumos existentes en su comunidad y cuidan su salud. El grado de aceptación del huerto escolar fue sobresaliente en la comunidad dada la participación de alumnos y padres de familia al producir sus propios alimentos y al obtener conocimientos para mejorar sus hábitos alimenticios.
Severe Symptomatic Hypocalcaemia Associated with Zoledronic Acid in a Patient of Ca Prostate: Case Report and Literature Review
Authors: Sharma Ritu , Singh Kaalindi , Negi R R
Published: July 2022

Zoledronic acid is a parenteral long acting bisphosphonate that has been used widely in the management of osteoporosis, bone metastasis and malignancy induced hypocalcaemia. Zoledronic acid is well tolerated but rarely severe hypocalcaemia and nephrotoxicity may occur. Here we report a case of 62 year male patient of metastatic Ca prostate who had severe hypocalcaemia after receiving intravenous zoledronic acid and docetaxel. Patient was hospitalized and managed with intravenous calcium supplementation and remained admitted for several days. Post recovery he was again started on zoledronic acid therapy and chemotherapy.
Incidence of transplant renal artery stenosis (TRAS) and graft characteristics in renal transplant recipients with multiple renal arteries: A prospective observational study
Authors: Sharma Manish , Sharma Uma
Published: July 2022

Background: This was a prospective observational study to evaluate the incidence of Transplant Renal Artery Stenosis (TRAS) and Graft characteristics in Renal Transplant Recipients with Multiple Renal Arteries. Material andMethods: In the present study 25 patients’ recipients of multiple renal artery graft kidney who underwent renal transplant after 30 the June 2016 till October 2017 with post-transplant serum creatinine ≤ 1.5mg/dl were included and evaluated for stenosis by CT Angiography done after period of 90 days. Results: In this study double renal artery was present in 96% patients and triple renal artery was present in 4% of patients. Only left laparoscopic donor nephrectomy was done in all the cases. Arterial reconstruction was done by three techniques – double barreling done in 48% of cases, Y graft in 20% of cases and end to side anastomosis to main renal artery in 32% cases. Reconstructed renal artery was anastomosed to recipient external iliac artery by end to side anastomosis in 24% of patients and recipient internal iliac artery by end to end anastomosis in 76% of cases. Loupe was used during surgery in 28% of cases. Atheroma was present in 4% of donor vessels and 4% of recipient vessels. There was no technical difficulty in positioning of kidney in any of cases. There was incidence of delayed graft functioning in 8% of cases. There was no evidence of TRAS in any of cases on CT Angiography. There was no evidence of contrast induced nephropathy in this study group. Conclusion: In conclusion, there was no evidence of TRAS was found in any case. Hence no association could be established between occurrence of TRAS and various factors in patients with multiple renal artery live donor transplants with reconstruction.
Nanomaterials – The Modern Age Frontier in Implant Dentistry
Authors: Keerthi T , Purushotham Sahana
Published: July 2022

Nanomaterials advent has contributed significantly in various lines of medicine and dentistry. This review article discusses about the various properties and the different nanomaterials indicated in periodontal regenerative medicine and implant dentistry. Various materials like chitosan, PLGA particles, Bioceramics etc have been introduced with unique properties like enhanced biocompatibility and osteogenic potential; along with newer additions of biomaterials with antimicrobial properties like Zinc oxide, Silver and Gold. This increasing interest in the field of nanomaterials has given rise to Nanotoxicology, a newer branch of science dealing with their associated toxicities in humans along with their environment. This gives us an opportunity for enhanced nanomaterials in the future with diverse advancements, for their direct application in clinical dentistry.
Different Applications of Stem Cells Therapy for Degenerative Retinal Diseases
Authors:   Department of Biotechnology and Medical-Surgical Sciences, “Sapienza” University of Rome, 04100 Latina, Italy, Florido Antonio , Budini Mauro ,   Department of Biotechnology and Medical-Surgical Sciences, “Sapienza” University of Rome, 04100 Latina, Italy
Published: July 2022

Retinal degenerative diseases, such as Stargardt’s disease (SD), glaucoma, retinitis pigmentosa (RP), age-related macular degeneration (AMD) or diabetic retinopathy (DR), represent the main causes of a decreased quality of vision and blindness worldwide. The progression and management of these conditions have always represented a challenge, but promising new evidences about the efficacy of mesenchymal stem cells (MSCs) as therapy for these diseases has been shown. The therapeutic potential of MSCs lies on its ability to release paracrine factors with neuroprotective, immunomodulatory and anti-angiogenic properties that stimulate the retinal pigmented epithelium (RPE) and are even similar to those produced by RPE. In literature we can find many studies conducted animal models, in which MSCs proved their efficacy in stopping the progression of retinal degeneration and for rescuing photoreceptors in the dormant phase. Furthermore, they retain a differentiation potential which allow them to differentiate into various cell types, including the cells of the retina. By all of those properties it is clear how MSCs result an important therapy option in these pathologies. In this review we summarize the various properties of MSCs and their promising applications in various retinal diseases, enhanching a new clinical approach on pathologies which otherwise have a difficult managing and a unfavorable prognosis.
Financial Innovation Strategies and Performance of Commercial Banks in Kenya
Authors: Mukira Abubaker Ramathan , Kariuki Paul , Muturi Willy
Published: July 2022

Purpose: The purpose of the study was to establish the impact of financial innovation strategies on performance of commercial banks.

Methodology: The study used census approach and targeted all the 41 commercial banks in Kenya. This is because the population is small. Senior Operations and the Senior Finance managers working in the headquarters of the commercial banks were targeted.  This was therefore a total of 82 respondents. The research adopted cross-sectional survey. The study used both primary and secondary data. Primary data was collected using questionnaires while Secondary information was acquired from the commercial banks' audited financial statements. After quantitative data was obtained through questionnaires, it was prepared in readiness for analysis and keyed into statistical package for social sciences (SPSS) computer software (version 22) for analysis.

Findings: Results from both primary and secondary data showed that financial innovation strategies had a positive and significant effect on performance of commercial banks.

Recommendation: Policy makers have to be wary about increasing level of competition in the banking industry and put in place appropriate competitive strategies to mitigate the challenges that come with the competition. These competitive strategies will enhance their performance and eventual survival in the industry.
PENGARUH TERAPI REFLEKSI KAKI TERHADAP PENURUNAN TEKANAN DARAH PADA LANSIA HIPERTENSI DI KECAMATAN CAMPURDARAT KABUPATEN TULUNGAGUNG
Authors: Nizar Angga Miftakhul , Farida Farida
Published: July 2022

Hypertension is a contributor to death from non-communicable diseases by 60%. The purpose of this study was to determine the effect of giving foot reflexology therapy on blood pressure in the elderly in Campurdarat District. The research design used a quasi-experimental approach with a pre-post test design approach. The number of research samples was 116 respondents who were selected using purposive sampling. The results showed that the difference in mean blood pressure before and after foot reflexology therapy was 14 mmHg for systolic and 11 mmHg for diastolic. Based on the statistical paired T Test where the level of significance or p (0.05) obtained a P value of 0.001 so that the P value < value, therefore there is the Effect of Foot Reflexology Therapy on Blood Pressure in Hypertensive Elderly in Campurdarat District, Tulungagung Regency in 2022. The results of This study proves that reflection therapy can reduce blood pressure in the elderly with hypertension. The provision of foot reflexology therapy must be balanced with regular exercise, control of diet, and consumption of drugs according to indications to get optimal results.