bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of SHINBARO2 on Rat Models of Lumbar Spinal Stenosis
Authors: Park So Hyun , Hong Ji-Young , Kim Won Kyung , Shin Joon-Shik , Lee Jinho , Ha In-Hyuk , Chung Hwa-Jin , Lee Sang Kook
Published: April 2019

Lumbar spinal stenosis (LSS) is a major cause of chronic low back pain; however, only a few therapies which have been used in clinics still have limited effects on functional recovery. SHINBARO2 is a refined traditional formulation for inflamed lesions and relieve pain of muscular skeletal disease. This study aimed at investigating the effects of SHINBARO2 on LSS and at determining its underlying molecular mechanism in rat models. The LSS rat models were set up by surgical operations in 6-week-old male Sprague-Dawley rats. SHINBARO2 was orally or intraperitoneally administered for 14 days. The motor and sensory ability of rats were evaluated using the activity cage and hot plate method. On the termination day, total vertebrae including the disc and spinal cord were excised for ex vivo study. SHINBARO2 improved locomotor functions and pain sensitivity in LSS rat models. Mechanism study suggested that SHINBARO2 inhibited the production of nitric oxide and prostaglandin E2in tissues from LSS-induced rats. SHINBARO2 also suppressed the expression of proinflammatory cytokines including tumor necrosis factor-αand interleukin-1β. The activation of NF-κB by LSS surgery was effectively reduced by SHINBARO2, which coincided with the inhibition of IκB degradation. In addition, brain-derived neurotrophic factor (BDNF), a potent promoter of neurite growth, and its downstream ERK signaling were also regulated by SHINBARO2. These findings suggest that the effect of SHINBARO2 might be associated in part with the anti-inflammation and pain control in LSS rat models.
Influência da gramática filosófica no conceito de verbo em gramáticas brasileiras
Authors: Prete Mairus Antonio
Published: April 2019

Nosso objetivo no presente artigo é analisar a influência da gramática filosófica no conceito de verbo presente em gramáticas publicadas em dois momentos da gramaticografia brasileira: o final do século XIX e o início do século XX; o final do século XX e o início do século XXI. Para isso, descrevemos os critérios distintivos do conceito de verbo em gramáticas filosóficas, como a de Jerônimo Soares Barbosa, e depois comparamos com os conceitos presentes nas gramáticas que selecionamos para nosso corpus. Esse procedimento nos levou a constatar que os conceitos de verbo das gramáticas selecionadas apresentam critérios distintivos se- melhantes ao da gramática filosófica, fato que relativiza a ideia de que esta seja uma tradição totalmente superada pelas gramáticas publicadas na transição do século XIX para o XX, ou uma tradição irrelevante em gramáticas publicadas na transição do século XX para o XXI. Realizamos esta pesquisa com base nos pressupostos da História das Ideias Linguísticas (AUROUX, 2009), corrente para a qual a acumulação de conhecimento é fundamental seu desenvolvimento na longa duração do tempo.
Entries on the History of Corpus Linguistics
Authors: Assunção Carlos , Araújo Carla
Published: April 2019

Corpus linguistics is anchored in a theoretical paradigm characterised by an empiricist approach and as well as by a conception of language as a probabilistic system. In linguistics, empiricism Empiricism is an approach that grants primordial status to data coming from the observation of language, generally grouped together in a corpus, as opposed to rationalism Rationalism. Rationalism is based on the study of language through introspection, which is regarded as a way of assessing models of structural functioning and the formation of the cognitive process of language. As a result, there is a chasm between the philosophical perspectives characteristic of the empiricist and rationalist conceptions of language, represented by its main contributors. On the one hand, there is Halliday, a representative of the empiricist conception, and, on the other hand, Chomsky, the greatest figure of Rationalism rationalism in linguistics. However, new approaches need to be taken into consideration. From all these conceptions the greatest number of works of corpus linguistics has been derived, in the areas of lexicography and terminology – production of dictionaries, glossaries, terminological databases, etc.
Consumed by obsession: Career adaptability resources and the performance consequences of obsessive passion and harmonious passion for work
Authors: Amarnani Rajiv K , Lajom Jennifer Ann L , Restubog Simon Lloyd D , Capezio Alessandra
Published: April 2019

Does passion predict performance? Whereas harmonious passion is typically associated with strong performance, evidence for the obsessive passion-performance relationship has been so far inconclusive. The mixed results in the literature suggest that there are hitherto unexamined boundary conditions and mechanisms shaping the relationship between obsessive passion and performance. This study draws on principles from conservation of resources and the dual-systems model of self-regulation to explain how these two types of passion (obsessive and harmonious) relate to work performance. We examined career adaptability as a buffer that determines when and for whom obsessive passion precipitates emotional exhaustion as well as when and for whom emotional exhaustion diminishes work performance. This proposed moderated mediation model was tested in two multisource samples in corporate ( N = 139 employee-supervisor dyads) and healthcare sectors ( N = 156 time-lagged employee-peer dyads) respectively. We observed support for the proposed model in both samples. Career adaptability prevents obsessively passionate workers from being consumed by obsession.
Increasing Risks for Armed Conflict: Climate Change, Food and Water Insecurity, and Forced Displacement
Authors: Levy Barry S.
Published: April 2019

The interrelated factors of climate change, decreased access to freshwater, and forced displacement are heightening the risk of armed conflict. Higher temperatures and extremes of precipitation are contributing to food and water insecurity, forced displacement, and sociopolitical tensions. Health professionals can help to address these problems through education, advocacy, and other activities that aim to mitigate and adapt to climate change and minimize the risk of armed conflict.
Learning to be a mother: Comparing two groups of Chinese immigrants in the Netherlands
Authors: Zheng Lijie , de Haan Mariëtte , Koops Willem
Published: April 2019

Immigrant parents may have to rebuild their parenting knowledge after migration to keep up with their new milieu. Comparing two subgroups of Chinese immigrants, economic and knowledge immigrants, this study shows that the construction of different parental ethnotheories can be understood through the characteristics of their parenting knowledge acquisition, social networks and networking strategies. Findings from ego-network interviews with 15 economic immigrant mothers and 20 knowledge immigrant mothers indicate that the former tends to obtain practical tips and specific instructions directly from experts and acquire practical help from local, co-ethnic, small and dense networks, while the latter engages in critical peer-based learning in multicultural, open and long-distance networks. This study argues that a social network perspective can shed light on the “black box” of how parenting theories are reconstructed after migration.
Serum levels of interleukin-6, interleukin-8, interleukin-10, and tumor necrosis factor-α, renal function biochemical parameters and clinical outcomes in pediatric cardiopulmonary bypass surgery
Authors: Gorjipour Farhad , Totonchi Ziya , Gholampour Dehaki Maziar , Hosseini Saeid , Tirgarfakheri Koroush , Mehrabanian Mohamadjavad , Mortazian Meysam , Arasteh Manesh Shaghayegh , Rahab Mehdi , Shafighnia Shora , Taiyari Saeed , Gorjipour Fazel
Published: April 2019

Background:

Cardiopulmonary bypass causes detrimental effects on remote organs due to inflammatory response. One of these organs is kidney that is frequently affected by cardiac surgery. Acute kidney injury is a post-cardiopulmonary bypass complication, which may result in increased post-operative morbidity and mortality. Post-cardiopulmonary bypass inflammatory response may contribute to remote organ dysfunction. In the present study, we investigated the relation between cytokines including interleukin-6, interleukin-8, interleukin-10, and tumor necrosis factor-α, and renal function tests such as creatinine and blood urea nitrogen (BUN).

Methods:

In total, 91 patients between the ages of 4 and 60 months were enrolled for elective cardiac surgery with cardiopulmonary bypass after informed consent. Data regarding renal function tests and clinical outcomes were carefully recorded until 24 hours after admission to intensive care unit and analyzed.

Results:

Our findings support that there is a direct correlation between cytokines including interleukin-6, interleukin-8, interleukin-10, and tumor necrosis factor-α and cardiopulmonary bypass time, duration of operation, and intensive care unit stay. Longer cardiopulmonary bypass time was associated with higher interleukin-8 at cross-clamp removal and 24 hours post- intensive care unit as well as higher interleukin-10 at declamp time. Higher interleukin-6 at declamp time was directly correlated with higher post-operative BUN. Interleukin-8 level after anesthesia induction was directly correlated with intensive care unit stay duration. Higher blood interleukin-6 and tumor necrosis factor-α levels following 24 hours of admission to intensive care unit were associated with longer mechanical ventilation time.

Conclusion:

Higher circulatory pro-inflammatory cytokine level is associated with adverse outcomes such as increased intensive care unit stay and longer mechanical ventilation time in pediatric patients. It is also correlated with unfavorable biochemical parameter of renal function, BUN. Findings hint that proper control of the inflammatory response is vital for the control of unfavorable clinical and pathological outcomes.
Veno-venous extracorporeal life support for blastomycosis-associated acute respiratory distress syndrome
Authors: Al-Fares Abdulrahman , Fan Eddy , Husain Shahid , Di Nardo Matteo , Cypel Marcelo , Keshavjee Shaf , Herridge Margaret S , Del Sorbo Lorenzo
Published: April 2019

Background:

Blastomyces is a dimorphic fungus endemic to regions of North America, which can lead to pneumonia and fatal severe acute respiratory diseases syndrome in up to 89% of patients. Extracorporeal life support can provide adequate oxygenation while allowing the lungs to rest and heal, which might be an ideal therapy in this patient group, although long-term clinical and radiological outcomes are not known.

Clinical features:

We report on five consecutive patients admitted to Toronto General Hospital intensive care unit between January 2012 and September 2016, with progressive respiratory failure requiring veno-venous extracorporeal life support within 24-96 hours following mechanical ventilation. Ultra-lung protective mechanical ventilation was achieved within 24 hours. Recovery was the initial goal in all patients. Extracorporeal life support was provided for a prolonged period (up to 49 days), and four patients were successfully discharged from the intensive care unit. Long-term radiological assessment in three patients showed major improvement within 2 years of follow-up with some persistent disease-related changes (bronchiectasis, fibrosis, and cystic changes). In two patients, long-term functional and neuropsychological outcomes showed similar limitations to what is seen in acute respiratory distress syndrome patients who are not supported with extracorporeal life support and in acute respiratory distress syndrome patients without blastomycosis, but worse pulmonary function outcomes in the form of obstructive and restrictive changes that correlated with the radiological imaging.

Conclusion:

Veno-venous extracorporeal life support can effectively provide prolonged support for patients with blastomycosis-associated acute respiratory distress syndrome that is safe and associated with favorable long-term outcomes.
‘It was peaceful, it was beautiful’: A qualitative study of family understandings of good end-of-life care in hospital for people dying in advanced age
Authors: Gott Merryn , Robinson Jackie , Moeke-Maxwell Tess , Black Stella , Williams Lisa , Wharemate Rawiri , Wiles Janine
Published: April 2019

Background:

Hospitals are important sites of end-of-life care, particularly for older people. A need has been identified to understand best practice in hospital end-of-life care from the service-user perspective.

Aim:

The aim of this study was to identify examples of good care received in the hospital setting during the last 3 months of life for people dying in advanced age from the perspective of bereaved family members.

Design:

A social constructionist framework underpinned a qualitative research design. Data were analysed thematically drawing on an appreciative enquiry framework.

Setting/participants:

Interviews were conducted with 58 bereaved family carers nominated by 52 people aged >80 years participating in a longitudinal study of ageing. Data were analysed for the 21 of 34 cases where family members were ‘extremely’ or ‘very’ satisfied with a public hospital admission their older relative experienced in their last 3 months of life.

Results:

Participants’ accounts of good care aligned with Dewar and Nolan’s relation-centred compassionate care model: (1) a relationship based on empathy; (2) effective interactions between patients/families and staff; (3) contextualised knowledge of the patient/family; and (4) patients/families being active participants in care. We extended the model to the bicultural context of Aotearoa, New Zealand.

Conclusion:

We identify concrete actions that clinicians working in acute hospitals can integrate into their practice to deliver end-of-life care with which families are highly satisfied. Further research is required to support the implementation of the relation-centred compassionate care model within hospitals, with suitable adaptations for local context, and explore the subsequent impact on patients, families and staff.
Traffic Oscillation using Stochastic Lagrangian Dynamics: Simulation and Mitigation via Control of Autonomous Vehicles
Authors: Zheng Fangfang , Lu Liang , Li Ruijie , Liu Xiaobo , Tang Youhua
Published: April 2019

The phenomenon of stop-and-go waves is frequently observed in congested traffic. With the development of connected and autonomous vehicle (CAV) technologies, it is possible to reduce traffic oscillation via control of CAVs in a mixed traffic flow with both human drivers and autonomous vehicles (AVs). This paper introduces a stochastic Lagrangian model which is capable of simulating stop-and-go traffic considering the heterogeneity of drivers. The sample paths of the stochastic process are smooth without aggressive oscillation. The model is further extended to the mixed traffic flow condition, considering stochastic human driving behavior and deterministic behavior of AVs. With the proposed model, the variation of performance of AV control strategies can be quantified in addition to the average performance. A numerical example with a single lane circular road is used to investigate the impact of the AV control strategy on mitigating stop-and-go waves. Both qualitative and quantitative results show that the phenomenon of stop-and-go waves can be reduced significantly with only one AV, while the increase of AVs from 10% (two AVs) to 50% (10 AVs) offers just marginal improvement in relation to the ensemble-averaged performance and 95% confidence interval of the ensemble-averaged performance. The proposed simulation approach based on the stochastic Lagrangian model can effectively investigate the impact of AV control strategies on traffic oscillation, considering in particular the uncertainty of human driver behavior.
Exercise Testing of Adolescents and Young Adults With Sickle Cell Disease: Perceptual Responses and the Gas Exchange Threshold
Authors: Ameringer Suzanne , Elswick R. K. , Sisler India , Smith Wally , Lipato Thokozeni , Acevedo Edmund O.
Published: April 2019

For individuals with sickle cell disease (SCD), mild to moderate exercise is advised, but self-regulation of these intensities is difficult. To regulate intensity, one SCD recommendation is to stop exercising at the first perception of fatigue. However, perceived effort and affect (how one feels) are perceptual cues that are commonly used to guide exercise intensity. This study (a) examined perceived effort, affect, and fatigue in relation to metabolic state (gas exchange) in adolescents and young adults (AYAs) with SCD, (b) explored guidelines AYAs use to self-regulate exercise, and (c) compared perceived effort and affect at gas exchange threshold (GET) with healthy counterparts. Twenty-two AYAs with SCD completed an incremental cycle test. Perceived effort, affect, and fatigue were assessed every 2 minutes. A mixed-effects linear model was conducted to model changes in effort, affect, and fatigue across time. Mean scores of effort and affect at GET were compared with published data of healthy counterparts. Participants were queried about self-regulation exercise strategies. Findings indicated that both perceived fatigue and effort at GET was lower than expected. Perceived effort was lower ( p < .0001), and perceived affect was significantly higher ( p = .0009) than healthy counterparts. Interviews revealed that most participants (95%) do not stop exercising until fatigue is moderate to severe, and many (73%) do not stop until symptoms are severe (chest tightness, blurry vision). Nurses should review guidelines for safe exercise with AYAs with SCD. Exercise training may be beneficial to AYAs with SCD for learning how to interpret bodily responses to exercise to improve self-regulation.
Music mavens revisited: Comparing the impact of connectivity and dispositions in the digital age
Authors: Verboord Marc
Published: April 2019

This article aims to contribute to work on music mavenism with the explicit goals to analyze how important connectivity (e.g. someone social network) is in the way music spreads, compared to dispositions (schemes of perception and appreciation). Concretely, I study how individuals find new music and who are involved in spreading information on music. I use data from a representative survey on the Dutch population to examine this. Music discovery can be characterized by three types of practices: individualized networks, traditional expertise, and mass media. The results also show that successful influencers – mavens – differ only slightly from these listeners who are highly involved in exchanging music tips. Dispositions – particularly cultural capital – remain highly influential in explaining not only how people find music but also who recommends music and still seem to be more important than connectivity.
Aerodynamic performance of the supersonic parachute with material permeability
Authors: Yang Xue , Yu Li , Nie Shunchen , Zhang Siyu
Published: April 2019

A new flow field model was established to simulate compressible flow around porous canopy. The compressible Ergun equation was introduced into the source term of momentum equations for the first time to study the influence of material permeability on aerodynamic performance of supersonic parachutes. By using this method, the dynamic variations of related flow field results such as flow structure, drag performance and shock wave standoff distance were obtained. Numerical results including shock wave shape and the average value of drag coefficient are in accordance with the wind tunnel test results. The numerical results show that the velocity-penetrating fabric makes the wake vortex area become narrower and move backward. With the increase of material permeability, the oscillation amplitude and the average value of drag coefficient decrease. This new method can be a good supplement in parachute design and research. It also instructs how to choose fabric for supersonic parachutes.
Usefulness of plateletcrit in the prediction of major adverse cardiac and cerebrovascular events in patients with carotid artery stenosis
Authors: Aslan Serkan , Demir Ali Rıza , Demir Yusuf , Taşbulak Ömer , Altunova Mehmet , Karakayalı Muammer , Yılmaz Emre , Gürbak İsmail , Ertürk Mehmet
Published: April 2019

Objectives

Platelets play an important role in the pathogenesis of atherosclerosis and the physiopathology of cardiovascular events. Plateletcrit provides complete information on total platelet mass. The relationship between plateletcrit values and long-term outcomes in patients with carotid stenosis is not known. The purpose of the present study is to evaluate the reliability of plateletcrit for predicting major adverse cardiac and cerebrovascular events (MACCE) in patients with carotid stenosis.

Methods

A total of 230 patients with more than 50% stenosis of the carotid artery were retrospectively included in this study. All cases were divided into two groups according to the calculated threshold value of plateletcrit with receiver operating characteristics curve and baseline parameters and clinical outcomes were compared. Univariate and multivariate analyses were used to evaluate the association between the plateletcrit and MACCE.

Results

The cut-off value for plateletcrit was found to be 0.233 for predicting MACCE, with 56.2% sensitivity and 68.0% specificity. High plateletcrit levels were demonstrated to be statistically higher in patients with MACCE (0.247 in the MACCE (+) group vs. 0.213 in the MACCE (–) group, p < 0.001). In the Kaplan–Meier survival analysis, the long-term mortality rate was higher in the high plateletcrit group ( p = 0.006). Multivariate regression analysis showed that plateletcrit was independently associated with MACCE (OR: 2.196, CI: 1.200–4.018; p = 0.011).

Conclusions

Our data suggest that plateletcrit has an independently predictive value for long-term mortality and MACCE, and it can be used as a marker to predict the long-term adverse outcomes in patients with carotid stenosis.
From the margin to the centre? A relational analysis of discursive contention in the minority integration debate in the Low Countries
Authors: Berbers Anna , Uitermark Justus , Traag Vincent A , d'Haenens Leen
Published: April 2019

Minority integration is a highly contested topic in public debates, and assimilationist actors appear to have gained discursive ground. However, it remains difficult to accurately depict how power relations in debates change and evolve. In this study, the public debates on minority integration in Flanders and the Netherlands between 2006 and 2012 are studied to ascertain changing power relations. We use a relational method to identify clusters formed through discursive contention and study polarization in the debates as well as several aspects of discursive power between and within clusters. In the Netherlands, a pattern identified in earlier research is reproduced, whereby a unified but small cluster of assimilationists with strong discursive leaders is able to dominate the debate on integration. In Flanders, group consolidation is too low, so the clusters cannot be viewed as cohesive groups. Another difference to the Dutch debate is that the volume of opinion articles is much lower and the actors in the Flemish debate are more often foreign opinion leaders. We conclude that the assimilationists have increased their discursive power in the Dutch debate, while the anti-assimilationists have lost power. The stark contrast between the Dutch and Flemish discursive landscape highlights the need for more research on the causal mechanism behind discursive struggles.
Childhood Adversity and Internalizing Problems: Evidence of a Race Mental Health Paradox
Authors: Kysar-Moon Ashleigh
Published: April 2019

Health disparities scholars describe the existence of a race mental health paradox—specifically, when black adults face higher levels of adversity compared with whites yet have similar or better mental health outcomes. Whether such a paradox exists among youth is unclear. Using data from the Longitudinal Studies of Child Abuse and Neglect, I examine black–white differences in children’s internalizing problems scores and consider the role of childhood adversities. Black children experience more adversity within family and neighborhood domains and cumulatively across ecological levels yet have comparable or better mental health at age 4 that endures over the early life course compared with white children ( p < .05). Evidence suggests that among children with the greatest adversity (at the parent level), having three supportive adults and high degrees of support at age 6 were more effective for black youth than their white peers in diminishing risk for internalizing problems later in childhood ( p < .05).
How professional memory influences vocational teachers’ perception of changes related to students
Authors: Sirk Meidi , Liivik Reeli , Ümarik Meril , Loogma Krista
Published: April 2019

Kutseõpetajate professionaalsust mõjutavad oluliselt õpilaskonna muutused, millega on kaasnenud uued nõudmised tööle. Varasemates uurimustes on rõhutatud, et muutuste kogemisele avaldab mõju professionaalne mälu, mis sisaldab ametialaseid mälestusi ja sündmusi, kujundades nende kaudu professionaalseid teadmisi ja tööalaseid tavasid. Käsitledes professionaalset mälu kui ühte kutseõpetajate professionaalsuse karakteristikut, oleme seadnud uurimuse eesmärgiks selgitada kutseõpetajate kogetud muutusi õpilaskonnas, tuginedes professionaalse mälu kontseptsioonile. Artikkel põhineb kombineeritud uurimisviisil, kus andmeid koguti kvantitatiivse küsitluse ja kvalitatiivse poolstruktureeritud intervjuudega. Uurimistulemustest ilmneb, et lühema staažiga ja nooremad kutseõpetajad kogevad muutusi õpilaskonnas positiivsemalt kui pikema staažiga ja vanemad kutseõpetajad. Lisaks mõjutab muutuste kogemist töö kontekst. Õpilaskonna muutustele antud tähendused sõltuvad ühiskondlikest ja hariduspoliitilistest sündmustest, millega õpetajad on kokku puutunud, ning tööga seotud nostalgilistest mälestustest.
 Summary
КЛАССИФИКАЦИЯ АГНОНИМОВ В ПЬЕСЕ У. ШЕКСПИРА «КОРОЛЬ ЛИР»
Authors: Ershov Denis Ivanovich
Published: April 2019

Целью данного исследования является создание классификации агнонимов по тексту оригинала трагедии У. Шекспира «Король Лир».Методы исследования. В работе использованы следующие основные методы и приёмы исследования: общенаучные методы анализа, сравнения, описания (при работе с лексическим материалом). Интроспективный подход к тексту явился одним из основных при отборе материала для научной статьи. В исследовании также применялись: метод сплошной текстовой выборки, лексикографический метод, компонентный анализ лексической семантики, приёмы обобщения и классификации, метод дискуссии и анализа лексикографических данных социологического опроса.Результаты работы. В пьесе Шекспира «Король Лир» нами были определены три основные функции агнонимов – стилистическая, экспрессивная и прагматическая. Кроме того, были даны две классификации агнонимических рядов – групп агнонимов, объединенных по своим функциям. Первая классификация охватывала грамматические агнонимические ряды. Вторая – тематические. Для каждой классификации из текста анализируемого произведения были выбраны необходимые группы агнонимов. Были определены методы выявления и распознания агнонимов. Возникновение агнонимов в тексте нами было объяснено авторским специфическим замыслом, делающим текст его произведения оригинальным, своеобразным и неподражаемым в своей уникальной идентичности, с учётом теории релевантности с учётом текстовых категорий насыщенности неоднозначности при опоре на когнитивный подход – теорию реликтовых концептов.Область применения результатов: рекомендации по использованию результатов диссертационного исследования, отражённых в настоящей статье, состоят в возможности их применения при разработки лекционных и практических курсов по лексикологии, когнитивной лингвистике, истории английского языка, лингвистике текста, для проведения практических занятий по аналитическому чтению оригинальных текстов, а также при написании исследовательских работ разного уровня. Проведённый в работе анализ оригинального текста трагедии У. Шекспира «Король Лир» на предмет наличия в нём агнонимов может лечь в основу спецкурсов по исторической прагмалингвистике и аналитической лексикологии.
СПЛАХНОНИМИЧЕСКАЯ ЛЕКСИКА ВО ФРАЗЕОЛОГИЧЕСКИХ ЕДИНИЦАХ: ЛИНГВОПРАГМАТИЧЕСКИЙ АСПЕКТ
Authors: Nemchinova Natalya Viktorovna
Published: April 2019

Цель. Статья посвящена выявлению, описанию и анализу фразеологических единиц, содержащих наименование внутренних органов человека.Предметом анализа выступают фразеологические единицы русского языка со сплахнонимической лексикой. Авторы ставят целью рассмотреть выявленные фразеологические единицы с позиции лингвистической прагматики.Метод или методология проведения работы. Основу исследования образуют анализ и синтез эмпирического материала, его обобщение и классификация, а также дефиниционный анализ.Результаты. Результаты работы заключаются в том, что соматические фразеологизмы были расклассифицированы относительно намерений говорящего. Выбранные единицы для лингвистического анализа были описаны с применением основных положений лингвистической прагматики. Определены соматические единицы с прямым и скрытым воздействием на получателя информации.Область применения результатов. Результаты исследования могут быть применены в дальнейших научно-исследовательских работах, связанных с изучением фразеологических единиц, содержащих в своем составе соматизмы, а именно наименование внутренних органов человека.
Benefit Finding in Adults Treated for Benign Meningioma Brain Tumours: Relations with Psychosocial Wellbeing
Authors: Kangas Maria , Williams Janet R. , Smee Robert I.
Published: April 2019

Introduction: Research has indicated that individuals may report benefit finding (BF) as a result of experiencing potentially life-threatening traumatic events, such as being diagnosed with cancer or sustaining an acquired brain injury (ABI). No study to date has examined the incidence and correlates of BF in adult brain tumour samples. The present study aimed to investigate the association between BF and demographic and psychosocial variables in adults treated for a benign meningioma. Method: Seventy participants aged 36 to 87 years completed questionnaires that assessed perceived BF resulting from one's meningioma experience, intrusion and avoidance symptoms, emotional wellbeing and perceived quality of social support. Results: 39% of the sample had been diagnosed with their tumour within a 2-year period prior to assessment (‘early’ meningioma subgroup), while the remaining 61% of participants had been diagnosed with their tumour for more than 2 years (‘late’ meningioma subgroup). Almost two thirds (63%) of the sample reported deriving a moderate amount of BF due to their meningioma experience; although different psychological variables were found to be associated with BF according to group status. Whereas greater BF was found to be significantly associated with elevated depressive symptoms in the ‘early’ subsample, elevated BF was significantly positively correlated with intrusions and avoidance symptoms in the ‘late’ subsample. Conclusions: The findings indicate that BF may co-occur in context of both adaptive and positive illusory processes, which is consistent with the Janus-Face model of growth following adversity. The findings also support the use of psychosocial interventions to facilitate psychosocial adjustment following health crises.
Jazz education in Italy: Two case studies
Authors: Baker Malcom Lynn
Published: April 2019

This article arises from an interest in understanding the various ways that schools of jazz in Europe have engaged in various partnership relationships. Of particular interest are arrangements between public and private educational institutions, private educational institutions and for-profit venues, and non-degree-granting and degree-granting institutions. The following schools were selected for study: Jazz and Modern Music Department, Universidade Lusíada, Lisbon, Portugal; Escola Superior De Musica De Lisboa, Lisbon, Portugal; MusicTime Music School, Milan, Italy; Siena Jazz National Jazz Academy, Siena, Italy; and Kunst Uni Graz Jazz Department, Graz, Austria. This article will present the case studies of the Italian schools and comparisons of those schools to other European schools of the study.
Literary bioinformatics studies: The genetic code mystique
Authors: Zaretsky Adam
Published: April 2019

What is life and what does it mean to be in the living political universe of entitiness without rhyme or reason? Flappy exudate, a bag in a bag, corpuscles of corporeality, worms (or flesh tubes) with appendages, even the cult of first involution – these are our body pods and the hunger and thirst of being-in. How can the situation of anatomical form be analysed without the illusion of instrumentalized reflection? Perhaps by amalgamating the categories and their issues. The issuance of taxonomy is the actual fine muck of excrement, which every brick of ordered life leaks as exudence and decay. Deep thoughts leave a mucal snail trail of what was tabular-seeming about our bodily situation, our environs, our friends, our experiments and our nourishment. Especially in this current age of 露 露 and 娜娜 (Lulu and Nana), our first officially public transgenic kindred, the question becomes, ‘who are these free-living divergences and what does it mean to be the uber-ding beyond geoengineering’s capabilities?’.
Looking for an Acheulean hand-axe in messy knowledge
Authors: Vakula Matej
Published: April 2019

Scientific knowledge production is a domain of human excellence, but recently this position became progressively challenged by machine intelligence. Some human tasks will be conquered sooner; others, which include design, may still require human intuition. Would the automated knowledge production truly challenge the human, or is one just an extension – a prosthetic – of the other? What could be the place of art in such environment? Mess and messy scientific models have the potential to provide paradigm shifts in molecular modelling, cancer research and systems biology where not only living humans but also machine learning algorithms craft knowledge. Together with art they have the potential for different reading and re-framing, which are the qualities scientists are looking for when engaging works of art within their molecular modelling process. In my opinion, these are the same qualities scientists are also looking for in the outputs of machine learning and computational chemistry modelling.
Epigenetics and metaphor: Language of limits
Authors: Falomir Sofia
Published: April 2019

Because the term ‘epigenetics’ has been used in a wide array of inquires within the life-sciences, it has come to bear a significant number of meanings. And just as biologists cannot come to an univocal understanding on what epigenetics connotes, the effect that its study has had in challenging contemporary neo-Darwinian, genecentred paradigms is also unclear. Some scientists and philosophers go as far as to say epigenetics has eroded dichotomies central to modern western thought, such as nature and nurture, or genotype and phenotype – but the matter ignites a great deal of controversy. What seems unquestionable, however, is that the notion that genetic material is a ‘programme’ that simply manifests itself in an external correlative, thus accounting for the development of a living organism, seems to have – at the very least – shifted. Rather than attempting to pinpoint the implications of epigenetics in contemporary biology, this article focuses on the ‘literary’ dimension of scientific debate: instability of meaning, metaphorical shifts, a redrawing of margins and limits. Furthermore, it will be argued that metaphor does not merely have a pedagogical value in the field but rather works proactively throughout the genesis, development and morphology of science and theory. By outlining a ‘literary’ dimension in discussions around genetics one can identify what Squier refers to as ‘the epistemological value of the imprecise’, which in the case of epigenetics seems to have jeopardized not only the boundaries between genes and their external correlatives, but even challenged the frontiers of traditional disciplinary discourse.
Soilogic telepathies (Radio Aporia Libre): Exploring dirtier philosophies of creative interchange
Authors: Lancaster Linus
Published: April 2019

This article focuses on soils as more-than-human subjects who are both living entities and ‘lenses’ through which we may begin to rethink some of the conventional parameters of ecology, communication and even the grounding of some western philosophical traditions on which these boundaries have stood. Just as the very term ‘more-than-human’ potentially exceeds the relegation of both soilogic agents and animalities to subservient status, likewise this discussion embarks from a more-than-humanist (‘posthumanist’) position. As we attempt to interact with living systems and ways of being in broader, more expansive terms, it becomes possible to catch conceptual glimpses of less hierarchical ontologies as they are understood by some more-than-western cultures. I have also drawn inspiration from artistic, theoretical and political movements in the west that have sought to interrupt the primacy of Eurocentric humanism in institutions and philosophical arenas. This presages dirty thinking.
Landfill dominion: The economy of a man-made neo-paradise
Authors: Wightman Jenifer
Published: April 2019

Herman Daly once identified the absurdity of shipping Danish cookies to the United States; if efficiency were in fact ‘economic’, one might just e-mail the recipe, save the fuel, reduce the greenhouse gases and still enjoy the cookie. This argument playfully illustrates that resources are scarce, ideas are Inherently Not Scarce (INS) and current financial systems are inefficient and not ‘economical’. The unprecedented industry of 7.5 billion people is now concerned about the resulting scarcity and pollution of the finite resource base. Until humanity shares inherently-not-scarce ideas for effectively managing what is in a steady state, scarcity and pollution will be a constant source of crisis on the landscape. Since 2004, I have made transforming colour field paintings with mud taken from the most pristine to the most toxic landscapes of northeast United States of America (NE USA). Although difficult to see individually, microbes existing within mud photosynthesize pigments. As a species grows from individual to colony, it becomes visible as pointillist pigments amass horizontal blocks of transient colour. As these bacteria express themselves (i.e., live: consume, reproduce, deplete resources, release wastes), they exhaust their habitat and create an altered landscape suitable to a successor. Like us, bacteria are bound by the law of conservation of mass; they constantly select and reject resources from the finite landscape. The resulting processes of growth and decay are intimately linked inversions resulting in beautiful transforming colourfields. As evidenced by my vibrant and literal portraits made from mud, these simple, highly adaptable, single-cell organisms craft a unique, colourful and synthetic existence. As a model system, they exhibit a viable steady state of infinite expression in a finite landscape where life and landscape is an intimate, malleable and reciprocal whole. Here I discuss the beauty of our landfill paradises, made evident by mud taken at two different kinds of landfilled ecosystems in New York City.
The aesthetic approach of hyperspaces
Authors: Traperas Dimitrios , Kanellopoulos Nikolaos
Published: April 2019

We investigate the Fourth Spatial Dimension, also known as ‘hyperspace’, by researching the capabilities of the human senses from the perspective of art and technology. The geometric approach of the fourth spatial dimension is studied through mathematical logic and the properties of simple geometric hyper-solids are examined. Focusing on the different ways that scientists and artists approached the Hyperspatial cognitive perception, we propose new aesthetic approaches by researching the capabilities of the human senses/bio-sensors and the brain. We present an interactive art installation for approaching the hyper-sound, with reference to the Varèse and Helmholtz description, but also in conjunction with gravitational waves, an interactive art application about visualization of Hyperspace resulting from our evolution of the Hinton Coloured Cubes Method and an artistic approach to connect Johan Van Manen’s intuitive ‘hypersphere’ with the Quantum Geometry of String Theory, proposing a new cosmological model. Through these methods, a reasoning is developed between the objective scientific thought and the freedom that Art offers generating a practical result: a series of innovative audio and visual stimuli created via innovative audio-visual digital technology. Hence, we merge computer science with sensory technology and artistic knowhow, to define the required knowledge base that today can be found in an emerging professional, the ‘technartist’.
Intracystic Hemorrhage Complicating Polycystic Liver Disease in a 90-Year-Old Woman
Authors: Purdy Amanda C. , Grigorian Areg , Fernando Dayantha , Nahmias Jeffry , Demirjian Aram N.
Published: April 2019

Nonparasitic hepatic cysts are common benign tumors that are often asymptomatic and incidentally discovered on imaging. Intracystic hemorrhage is a rare complication of hepatic cysts. We review the literature and discuss a case of intracystic hemorrhage in a 90-year-old woman with polycystic liver disease. The patient underwent cyst aspiration and percutaneous drain placement with subsequent resolution of symptoms. To our knowledge, we report the oldest patient to present with hemorrhage into a hepatic cyst. This case presents unique challenges in management, both because of the patient's age and because of her polycystic liver disease.
Combined Immunodeficiency With Inflammatory Bowel Disease in a Patient With TTC7A Deficiency
Authors: Broome David T. , Young Andrew , Torbic Heather , Krishnan Sudhir , Gordon Ilyssa , Lai Keith , Rizk Maged , Rieder Florian
Published: April 2019

Tetratricopeptide repeat domain-7A (TTC7A) deficiency causing combined immunodeficiency with inflammatory bowel disease (IBD) is rare. This case report alerts physicians to the possibility of TTC7A deficiency causing combined immunodeficiency with IBD and also highlights some of the current treatment options. We describe a 19-year-old patient with a compound heterozygote TTC7A mutation causing combined immunodeficiency, IBD, and multiple intestinal atresia. Compound heterozygote TTC7A mutations are known to cause combined immunodeficiency and IBD. Although rare, clinicians should be alerted to this variant and should understand the general approach to treatment.
Analisis Pengaruh Curah Hujan dan Kecepatan Angin Terhadap Konstruksi Papan Reklame Single Pole Tipe Sumbu Tengah
Authors: Iskandar Norman , Damarjati Wahyu , Utomo M.S.K Tony Suryo
Published: April 2019

Kasus robohnya papan reklame masih cukup sering terjadi. Ketidakmampuan menahan beban diduga menjadi penyebabnya. Hal ini menjadi alasan perlunya dikaji ulang standarisasi keamanan yang telah ditentukan oleh pemerintah selaku pihak yang berwenang memberikan ijin. Pada artikel ini akan dibahas tentang hasil analisis terhadap papan reklame yang telah diberikan ijin untuk dipasang oleh pemerintah Kota Semarang dengan metode simulasi software berbasis FEM. Papan reklame yang dianalisis berukuran 4 x 6 m dengan pipa baja schedule 40 berdiameter 12in sebagai penumpu, baja siku 40 x 40 x 4 mm sebagai struktur truss, dan plat baja galvanis dengan luas 4 x 6 m setebal 0,2 mm. Data kecepatan angin dan curah hujan yang digunakan bersumber dari BMKG Kota Semarang, dengan variasi kecepatan angin adalah 15 m/s, 25 m/s dan volume curah hujan adalah 736 mm/hari. Dari hasil simulasi didapatkan nilai stress maksimal 1,025 x 108 Pa pada kecepatan angin 15 m/s, dan 2,754 x 108 Pa pada kecepatan angin 25 m/s untuk kondisi pembebanan berupa angin. Sedangkan nilai stress maksimal 1,029 x 108 Pa pada kecepatan angin 15 m/s, dan 2,762 x 108 Pa pada kecepatan angin 25 m/s untuk kombinasi beban angin serta curah hujan. Kedua nilai tegangan maksimum masih dibawah yield strength dari material pembentuk struktur, yaitu 235 MPa. Sehingga struktur aman digunakan pada kondisi pembebanan tersebut. Namun pada kecepatan 25 m/s, tegangan maksimum berada pada ±30 Mpa diatas yield strength, artinya struktur tidak aman apabila mengalami beban sebesar itu secara terus menerus dan riskan oleh tegangan fatigue. Gaya akibat air hujan pada struktur tidak terlalu signifikan. Besarnya selisih gaya antara gaya drag hujan dengan gaya drag air dan hujan selalu lebih kecil dari 50 N. Sehingga untuk perhitungan secara umum, besarnya gaya akibat air hujan bisa diabaikan.
Formation of medullary phloem in Argyreia nervosa (Burm. f.) Bojer
Authors: Kapadane Kilas K , Shelke Ravindra A , Gondaliya Amit D , Rajput Kishore S.
Published: April 2019

Histologically, family Convolvulaceae is characterised by the presence of successive cambia, medullary (internal/intraxylary) and interxylary phloem in majority of the species, whereas some of the members are devoid of successive cambia and medullary bundles. The present study on Argyreia nervosa (Burm. f.) Bojer showed the presence of medullary bundles while internal phloem was absent during the primary growth. As the secondary growth progressed, successive cambia initiated from the pericyclic parenchyma. Development of medullary bundles began along with the regular protoxylem and protophloem while formation of intraxylary phloem was observed only after the initiation of secondary growth. Medullary/intraxylary sieve elements began to develop from the marginal pith cells. In thick stems, small segments of internal cambium initiated between the protoxylem and internal phloem. This internal cambium was functionally unidirectional and produced internal phloem centripetally. Developmental particulars are described in details along with its significance.
Corrosion performance of cold deformed austenitic stainless steels for biomedical applications
Authors: Talha Mohd , Ma Yucong , Lin Yuanhua , Pan Yong , Kong Xiangwei , Sinha O.P. , Behera C.K.
Published: April 2019

Austenitic stainless steels possess an excellent balance of strength and ductility along with the high ability to further raise their strength during cold deformation (CD). Corrosion resistance of austenitic stainless steels (SSs) is affected by cold deformation because passive films on the surface of steels are expected to be modified. A low level of CD enhances the surface diffusion, which results in the formation of a stable passive film leading to an increase in the corrosion resistance in neutral chloride solutions. The chromium content in the passive film on a deformed steel surface is usually richer, with a higher Cr/Fe ratio than that formed on annealed steels. A higher chromium content makes surface films more stable, which improves the corrosion resistance. However, severe CD results in the formation of strain-induced martensite phase and deformation twins, which decreases the localized corrosion resistance by increasing the number of active anodic sites on the surface. The corrosion resistance, especially the pitting resistance, in SSs is diminished with increasing volume fraction of the martensite. In this review, we highlighted the failure modes of corrosion of stainless steel implants, factors affecting corrosion, and effect of CD on mechanical properties and emphatically on the corrosion resistance of SSs for biomedical applications.