bluuebunny/crossref_metadata_2025 huggingface dataset:
Rapid antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales: an implementation study
Authors: Reiber Claudine , Bodendoerfer Elias , Brugger Silvio D. , Eberhard Nadia , Hitz Eva , Hofmaenner Daniel A. , Herren Sebastian , Kolesnik-Goldmann Natalia , Manicini Stefano , Zbinden Reinhard , Zinkernagel Annelies S. , Hasse Barbara
Published: May 2023

AIMS OF THE STUDY: The goal of this descriptive study was to assess the performance as well as the extent of the clinical impact of rapid automated antimicrobial susceptibility testing in patients with bacteraemia due to Enterobacterales. We also aimed to analyse how rapid automated antimicrobial susceptibility testing influences clinical decision-making.

METHODS: This single-centre study conducted at the University Hospital of Zurich included data from all consecutive patients with Enterobacterales bacteraemia from November 2019 to October 2020. There was no control group. The primary outcome was the effect of rapid automated antimicrobial susceptibility testing on antibiotic therapy (no adjustment, escalation to a broader-spectrum antibiotic or de-escalation to a narrower-spectrum antibiotic). Rapid automated antimicrobial susceptibility testing results were further compared to susceptibility tests using European Committee on Antimicrobial Susceptibility Testing (EUCAST) standard methods and erroneous results were noted. Additionally, we investigated turnaround times for rapid automated antimicrobial susceptibility testing and routine diagnostic testing.

RESULTS: We analysed 106 patients with 116 episodes of bacteraemia due to Enterobacterales, with Escherichia coli and Klebsiella pneumoniae being the most frequent isolates. Almost 8% of pathogens were multidrug resistant. Rapid automated antimicrobial susceptibility testing showed category agreement in 98.4% of all interpretable cases. A significant reduction of more than 20 h in turnaround times could be achieved with rapid automated antimicrobial susceptibility testing compared to the routine diagnostic workflow. In the majority of cases, rapid automated antimicrobial susceptibility testing had no effect, given that the empirical therapy was already correct or circumstances did not allow for de-escalation. In 38.8% of cases, antimicrobial therapy was adjusted, whereas eight cases were de-escalated based on rapid automated antimicrobial susceptibility testing alone.

CONCLUSIONS: Rapid automated antimicrobial susceptibility testing may be a valuable and safe way to accelerate diagnosis. In particular, time to suitable therapy can be shortened in cases of incorrect therapy. However, physicians are reluctant to de-escalate antibiotic therapy based on rapid automated antimicrobial susceptibility testing alone, limiting its impact in everyday clinics. To further explore the potential of rapid automated antimicrobial susceptibility testing, a stringent/compulsory antibiotic stewardship programme would be a valuable next step.
Switch: Executando SPARQL sobre o Neo4j
Authors: Silva Thiago Sant’Helena da , Mello Ronaldo dos Santos
Published: May 2023

Este artigo detalha Switch, uma abordagem que facilita a construção de triplestores que suportam consultas utilizando SPARQL e armazenam dados no Neo4j. Para isso, são utilizados conceitos de processamento de linguagens e geração de código através de ações semânticas. A solução foi desenvolvida e é capaz de traduzir diversos tipos de consultas SPARQL. Experimentos demonstraram que a solução é viável em termos de tempo de processamento.
Engenharia e Avaliação de Features para Extração de Informação em Notas Fiscais
Authors: Darrazão Eduardo , Amorim Victor , Oliveira Krerley , Gomes-Jr Luiz
Published: May 2023

A correta identificação dos elementos constantes em notas fiscais eletrônicas é importante para diversas questões de fiscalização e transparência governamental, como identificação de sobrepreço em licitações públicas. Porém, esta identificação é um desafio tanto pela diversidade de produtos, quanto pelas variações e erros de preenchimento. Este artigo aplica técnicas de estado-da-arte em extração de informação para avaliar os melhores conjuntos de features para se aplicar em notas fiscais eletrônicas brasileiras. Os testes utilizaram dados de notas fiscais de medicamentos emitidas no Piauí em 2021.
Estudo Comparativo de Estratégias para o Pareamento de Nomes de Entidades na Língua Portuguesa
Authors: Medeiros Antônio Mamede Araújo de , Gonçalves Eduardo Corrêa
Published: May 2023

O pareamento de nomes de entidades é a tarefa que consiste em realizar a correspondência automática entre nomes de uma lista A com os de uma outra lista B, considerando a semelhança entre eles. Há muitas aplicações modernas e importantes para a tarefa, variando desde a identificação de registros duplicados em bases de dados até a otimização de sistemas comparadores de preços. Este trabalho realiza a avaliação de duas técnicas propostas para o pareamento de nomes em português. Experimentos realizados em uma base contendo nomes de produtos e serviços mostraram que a combinação da medida Jaro-Winkler com vetores TF-IDF e embeddings word2vec foi capaz de produzir os melhores pareamentos.
Coleta de Dados do Instagram sobre Ocorrências de Caravelas-Portuguesas na Costa Brasileira
Authors: Camargo Leonardo da S. , Rocha Heloisa , Nascimento Lorena S. do , Hara Carmem
Published: May 2023

Redes sociais geram dados em grande volume, que são de livre e fácil acesso, renováveis por serem gerados continuamente e em tempo real, e de longa duração. O objetivo deste trabalho é coletar postagens do Instagram para obter dados sobre a distribuição espaço-temporal de avistamentos da caravela-portuguesa (cnidário physalia physalis) na costa brasileira. Foram obtidas postagens do Instagram com informações que apontam o Instagram como uma possível fonte deste tipo de dado, dada a quantidade de postagens coletadas. Trabalhos futuros envolvem determinar a veracidade e abrangência das informações e desenvolvimento de um processo automatizado para periodicamente extrair novas postagens.
Role of Lesion-to-Background Activity Ratio and Background Activity in Optimization of Reconstruction Protocols for FDG PET/CT Images of Overweight Patients: A Phantom Study
Authors: Rezvani Samira , Ghafarian Pardis , Bakhshayesh Karam Mehrdad , Ay Mohammadreza
Published: May 2023

Background: The quality of positron emission tomography/computed tomography (PET/CT) images plays an important role in tumor detection. This imaging method often yields poor-quality images of overweight patients due to the high level of noise, originating from scattering and photon attenuation. Objectives: The point spread function (PSF) is mostly used to enhance the spatial resolution and signal-to-noise ratio (SNR); however, it is known to increase the edge artifacts. The time-of-flight (TOF) principle can reduce edge artifacts in PSF modeling and improve lesion detection, especially in the thorax. The present study aimed to assess these two new techniques by applying different reconstruction parameters. Materials and Methods: An in-house phantom with an inner diameter of 35 cm was used for the simulation of overweight patients. Lesion-to-background ratios (LBRs) of 2: 1 and 8: 1, as well as background activity concentrations of 3 and 5 kBq/cc, were considered in this study. The list-mode data were reconstructed with various reconstruction protocols, numbers of subsets, and filter sizes. Quantitative analyses, including the coefficient of variation (COV), SNR, and recovery coefficient (RC), were also carried out. Moreover, box-and-whisker plots were performed. Results: At LBR of 2: 1, by changing the protocol from ordered subset expectation maximization (OSEM) to OSEM + PSF + TOF, the median value of SNR for 13-mm lesions (37 mm) increased by 39.25% and 53.45% (42.22% and 56.21%), at background activity concentrations of 3 and 5 kBq/cc respectively. However, at LBR of 8: 1, the corresponding values were 33.22% and 48.94% (40.22% and 52.15%) at background activity concentrations of 3 and 5 kBq/cc respectively. Conclusion: The TOF protocols were strongly recommended for both background activity concentrations at LBR of 2: 1 and for the low background activity concentration at LBR of 8: 1, especially when using smaller filter sizes. Moreover, subset numbers of 18 and 24 were appropriate for all protocols. However, a smaller subset number was suitable when a low background activity concentration and a smaller filter size were applied, especially at a lower LBR.
Comparative analysis of depression, anxiety, stress, and eating disorders among working and nonworking women visiting community pharmacies in Lahore, Pakistan
Authors: Saeed Hamid , Shafqat Afifa , Hameed Nimra , Latif Amna
Published: May 2023

Anxiety and depression are common worldwide and often occur together. Anxiety can alter appetite, causing women to consume more food than usual, leading to changes in eating behavior and obesity. This comparative cross-sectional study compared the severity of depression, anxiety, stress, and eating disorders among working and nonworking women visiting community pharmacies. Data were collected through face-to-face interviews with 244 working women and 267 nonworking women. The data were analyzed using descriptive statistics, and a chi-square test was conducted to evaluate differences in the severity of depression, anxiety, stress, and eating disorders between the two groups of participants. Most participants were literate; approximately half of the working (50.82%) and nonworking women (55.06%) had a normal body mass index. There were significant differences between the working and nonworking women in terms of their education and physical activity levels (p < 0.05). Both groups were identified as being at risk of developing bulimia, but their ability to control eating habits differed significantly (p = 0.008). Most participants reported never using laxatives, diet pills, or diuretics to control their weight. Moreover, they reported that they had never received treatment for eating disorders or experienced thoughts of suicide. The study found no significant difference in depression (p = 0.085) and anxiety levels (p = 0.207) between working and nonworking women. However, a significant difference was found in stress levels between working and nonworking women (p = 0.001). Our study highlights a significant prevalence of psychological issues among working and nonworking women in Pakistan, impacting their eating habits and contributing to developing eating disorders and obesity. Interestingly, working women display higher physical activity levels, while nonworking women demonstrate better oral control to prevent eating disorders. To improve women's mental and physical well-being, we recommend prioritizing mental health interventions for all women, promoting healthy eating habits, supporting physical activity, and investigating underlying factors influencing psychological well-being.
Students’ Discipline Problems and Classroom Management Strategies to Cope with the Problems: Teachers’ Perspective
Authors: Maqsood Ahmed, Ishtiaq Hussain
Published: May 2023

The main purpose of this study was to get an insight into the perceptionsof teachers about student discipline problems and classroom managementstrategies adopted by them. Data were collected from 86 secondary schoolteachers, teaching in various Federal Government Institutions ofIslamabad, through the administration of the researchers-madequestionnaire. Additionally, semi-structured interviews from 6participants were also conducted to get in depth views of the teachers aboutthe discipline issues of students and their management strategies in thecontext of classroom and school. The focus of the study was oncharacteristics of students creating problems in the classroom, the mostfrequently occurring and major causes of discipline problems, andclassroom management strategies used by teachers to improve discipline.Teachers' opposed the practices of traditional punitive strategies inclassrooms; they suggested the use of soft disciplinary skills in case ofstudents' unwanted behaviour.
Teaching Grammar through Inductive Approach and Competence of Prospective Teachers
Authors: Sahibzada Shamim-ur-Rasul, Mushtaq Ahmad, Misbah Iqbal
Published: May 2023

In Pakistan, traditional grammar teaching is not fruitful as students are notperforming better. It was needed to find new grammar teaching method.So, the study aimed to see the effect of inductive grammar teachingapproach on the teaching competence of prospective teachers. The studywas quasi experimental by design. The major hypothesis of the study wasthe difference of observed grammar teaching competence of theprospective teachers taught grammar through inductive teaching approachand traditional teaching is not significant.
Exploring Parental Control and its Impact on Secondary Level Students’ Attitude Towards Studies
Authors: Mushtaq Ahmad, Farah Shafiq, Muhammad Nadeem Anwar
Published: May 2023

In the present study, we examined the relationship between parental controland secondary level students’ attitude towards studies. The population ofthe study was the male and female Secondary level students and theirparents of all the boys’ and girls’ government secondary schools of TehsilSargodha. A sample of 150 students of the10th class and their parents wereselected on an availability basis from the randomly selected 30 secondaryschools including 10 Boys and 20 Girls schools. Two self-developedresearch instruments including one for parents’ control and the other forstudents’ attitude were used. To analyse the data, statistical calculationsincluding frequency, percentage, mean score, standard deviation, t-test,one-way ANOVA and correlation were used. The findings showed that theparents with more public dealing professions tend towards the strict andhighly strict level of parental control and there exist a positive and moderaterelationship between parental control and students’ attitude towards studies.The study recommends that parent teacher regular meetings may beorganized for parents ‘awareness to adopt better control strategy.
Analisis Penilaian Kinerja terhadap Pendidik dan Tenaga Kependidikan pada SDIT At-Taqwa 2 Surabaya
Authors: Fauziyah Hikmatul , H.P Berlian Therapi , Ilyas M. Effendi
Published: May 2023

This study aims to find out how the performance appraisal conducted by SDIT At-Taqwa 2 Surabaya, on educators and their educational staff. Educators and educational staff are an important part of the running of the educational process, where it must be able to run well. The method used in writing this article is descriptive qualitative method of data collection and literature study. With the analysis that has been carried out by researchers, the following results are found, 1) What are the steps taken by the school principal in determining qualified teaching and educational staff. 2) Obstacles encountered in the process of assessing educators and educational staff, namely the difficulty of male teaching staff. 3) How do educators overcome the difficulties experienced by students. 4) Factors in the success of education at SDIT At-Taqwa 2. 5) There are teaching staff but not in accordance with the required criteria. 6) There are some educators who cannot recite properly and correctly 7) Institutions that are still relatively new and lack experience in learning. 8) Almost all teaching staff have not been certified by the education office. And so forth.
The Influence Of E-Commerce And Consumptive Behavior Of Students Of The Economic Education
Authors: Sinta B. Vovi , Afifah Siti , Ramadhani Rafika
Published: May 2023

This study analyzes the effect of e-commerce on consumptive behavior of undergraduate students of economics education study program at STKIP Nurul Huda Sukaraja in East OKU. This study uses a quantitative research design and path analysis techniques. Research data was taken through a questionnaire with a population of 32 students and research samples with population research. The initial hypothesis of this study assumes that there is an influence of e-commerce on student consumptive behavior. This indicates that students are able to manage or manage existing finances so that they are able to prioritize needs
Reflexões sobre pós-extrativismo a partir da percepção de educandos do curso de turismo
Authors: Vilani Rodrigo Machado , Oliveira Maria Amália Silva Alves de , Machado Carlos José Saldanha
Published: May 2023

O presente artigo tem por objetivo discutir o ecoturismo como alternativa econômica às atividades de mineração na Bacia do Rio Doce e avaliar a relevância do tema para a formação dos turismólogos. O rompimento das barragens de mineração localizadas nos munícipios de Mariana, em 2015, e Brumadinho, em 2019, resultaram em centenas de mortes e uma devastação socioambiental sem precedentes no Brasil. Diante dos impactos negativos dessa atividade toma-se o padrão primário-exportador como questão estruturante para a crítica proposta. A discussão pauta-se sobre levantamento realizado junto a educandos de Turismo de uma universidade federal da região Sudeste e pesquisa bibliográfica e documental. Como resultado, tem-se a discussão incipiente sobre pós-extrativismo no Brasil, particularmente na sua relação com (eco)turismo, e a relevância da temática apontada pelos educandos. São tecidas considerações gerais e específicas acerca das possibilidades do ecoturismo na região da Bacia do Rio Doce e propõe-se a inclusão da temática na grade curricular do curso de Turismo.
Exploring the practices of Extensive Reading in South Omo Secondary Schools. Selected Secondary Schools in focus
Authors: Mohammed Shure  , Anbesie Sapho Tseganesh
Published: May 2023

The main objective of this research is to explore the practice of extensive reading in six secondary schools in the South Omo zone. To achieve the objective of the research, a mixed research design was used. In line with this, questionnaires, interviews and observation were the main data collection tools through which English language teachers, librarians and students participated. Likewise, the analysis of the collected data was made through simple descriptive statistics (i.e., mean, Standard deviation and frequency). The finding of the study shows that students mainly were dependent on the school library. It was also found that students read for academic gain than for their pleasure time. This is found to be out of the extensive reading principles. It was also found that English teachers were using and promoting the extensive reading approach in their language classes. It is recommended that schools and public libraries should prepare reading materials that are at the level of the student’s reading competencies. Furthermore, English language teachers should plan a free reading program along with their school curriculum which is designed and appropriate for extensive reading. Keywords: Extensive Reading, reading fluency, Challenges, teacher’s role,
"Change Management Aspects in Developing the International Airport “Avram Iancu” Cluj-Napoca, Romania"
Authors:   Technical University of Cluj-Napoca, Baidoc Raluca , Niemann Jörg ,   Hochschule Düsseldorf, Kacso-Vidrean Lorand ,   Technical University of Cluj-Napoca, Jucan Daniela Corina ,   Technical University of Cluj-Napoca, Pisla Adria ,   Technical University of Cluj-Napoca
Published: May 2023

The International Airport “Avram Iancu” in Cluj-Napoca, Romania (AIAI) is a public organization, the second important international, and the first important regional airport in the country. This position must be preserved in the competition with the national and international airports but also as regional airport having “around” other five regional airports at a radius of 180 km. To implement goals and a change management process, an agreement was made to be conducted a PhD research activity to identify the pillar elements together with the possibility to identify new financial support. This paper presents the first steps on this demarche. The identified directions and “resources” and the target (3 million passengers) might be fulfilled by listening the “master voice”, the passengers. As long as the success criteria are typically unidentified, the performance measurement must start with an imposed reference (needs or wishes) that becomes a critical factor for success. The implementation progress must be monitored and the end-users feed-back to be consider for the project recalibration (synthetic), by redefining the success criteria and for the project effective control of objectives (analytic). The change triggering factors (CTF) and critical success factors (CFS) for identifying the need of change and the right moment for action within the change management are very important to achieve the established goal.
Information System Development for Receiving and Handling Customer Complaints in Public Services
Authors: Komarudin Komarudin
Published: May 2023

Good public service is one indicator of the success of a government in providing satisfaction for the community. Along with the development of information technology, the government is also trying to improve public services by developing information systems that make it easier for people to make complaints or complaints about public services. This research aims to develop an information system that can improve the receipt and handling of customer complaints on public services. The method used in this research is the waterfall method. Data will be collected through interviews with relevant parties in public services, direct observation of the existing complaint system, and literature study related to the development of information systems. The results of this research are expected to produce an effective and efficient information system in receiving and handling customer complaints in public services. In this case, the information system can facilitate customers in making complaints, as well as speeding up the handling process and responses from related parties. So that it is expected to increase customer satisfaction with the public services provided.
ATM Vehicle Location Privacy and Security Using End -To - End Quantum Key Crypto System
Authors:   Department of Electronics and Communication Engineering, E.G.S. Pillay Engineering College, Nagapattinam, Tamilnadu, India., R Sanjay , KS Sai Sivasankar , B Ragu , R Satheswaran , C Mathuvanesan
Published: May 2023

Internet-of-things (IoT) is the latest revolution in electronic industry after internet. Smart appliances, portable computing devices, mobile phones and handheld system dominates in IoT, because a large portion of world population use it. Major applications, mainly financial, e-commerce, information security and sensitive data-communication need special attention in terms of security. Device authentication, encryption, and key distribution are of vital importance to any Internet-of-Things (IoT) systems, such as the new smart city infrastructures. This is due to the concern that attackers could easily exploitthe lack of strong security in IoT devices to gain unauthorized access to the system or to hijack IoT devices to perform denial-of-service attacks on other networks. This creates a strong requirement for providing security solutions into these devices. Key Word: IOT; Communication; Data; Application; Server.
Topology optimization of Nose Landing Gear of Aircraft for weight reduction
Authors:   Department of Mechatronics Engineering, Dr. Mahalingam College of Engineering and Technology, Pollachi,  Tamilnadu, India, S Nishanth , E A Pranesh , M Giridharadhalan
Published: May 2023

Design, Analysis, test and validation process of a NLG brace assembly of aircraft is mentioned in this study. The Nose Landing Gear is designed with for the purpose of attaching landing gear and wheel Moreover works on weight reduction, cost reduction. Key Word: ANSYS, NLG.
Effect of Musa acuminata Starch concentration on the Disintegrant Activity of Paracetamol Tablets
Authors:   School of Pharmacy, Kampala International University Uganda., Muhangi Rodgers , Onchweri Albert N. ,   School of Pharmacy, Kampala International University Uganda, Josephat Maniga ,   Department of Microbiology, Kampala International University Uganda., Mercy Tenywa ,   School of Pharmacy, Kampala International University Uganda, Muchiri Jacqueline Njeri ,   School of Pharmacy, Kampala International University Uganda, Paul-Chima Ugwu Okechukwu ,   Department of Publication and Extension, Kampala International University Uganda.
Published: May 2023

Today, tablets are one of the most widely used pharmaceutical dosage forms. Both active pharmaceutical ingredients (API) and inactive ingredients such as disintegrants are found in pharmaceutical dosage forms. Disintegrants are essential for dissolving the tablet into small particles and increasing the surface area of the API when it is exposed to gastrointestinal fluids. As a result, choosing the right type and concentration of disintegrant is often the most important aspect in determining tablet quality. Effect of Musa acuminata starch concentration on the disintegrant activity of paracetamol tablets was now researched on. Starch from unripe banana fruits was extracted with distilled water and 0.05M sodium hydroxide. Banana starch powder at concentrations of 5, 10 and 15% w/w were used to formulate paracetamol tablets by direct compression. Starch powder and tablet properties were evaluated. Increase in concentration of banana starch powder from 5-15% w/w led to a decrease in disintegration time, weight variation, and an increase in friability. The tablets formulated from banana starch at all concentration were comparable to tablet properties in the standard BP 2009. The starch powder pH, true density, bulk density, tapped density, angle of repose, Hausner’s ratio and Carr’s index were 6.57, 1.51g/ ml, 0.55g/ml, 0.61g/ml, 32.3o , 1.11 and 9.90, respectively. The tablets exhibited disintegration time, weight variation, thickness, and friability values ranging from 0.55-0.44min, 1.66-0.59%, 4-3.39mm, 0.13- 0.55%, respectively. The tablets met acceptable Pharmacopoeia requirements at starch concentration studied. Results revealed that banana starch could be used as a disintegrant in paracetamol tablet formulation due its comparable properties with the standard BP 2009 specifications. Musa acuminata starch when used at concentration of 15% gives optimum disintegrant activity. Keywords: Musa acuminate, Starch concentration, Disintegrant, Paracetamol tablets
Evaluation of the Approach, Awareness and Practices on Sexually Transmitted Diseases among Medical Students at KIU Western Campus, Ishaka Town Bushenyi District, Uganda.
Authors:   Faculty of Clinical Medicine and Dentistry Kampala International University, Uganda., Johnathan Langol
Published: May 2023

Sexually transmitted diseases (STDs) still remain a great public health problem of major significance in most parts of the world. The incidence of acute STD is believed to be high among sexually active adolescents worldwide due to changes and development in their lives. The study aims at establishing the attitude, knowledge and practices on STDS among students studying at Kampala International University Western Campus in Ishaka town. The study aims at establishing the attitude, knowledge and practices on STDS among students studying at Kampala International University Western Campus in Ishaka town. A great percentage of anticipated respondents participated in this study making the response rate 96%. Among these respondents (65%) were males and (35%) were females. The age distribution of the respondents showed that most of the respondents (50%) were between 20- 25 years old. Respondents (50%) were followers of the Catholic faith and followed other religions. The majority (76%) of the respondents were living near campus and (24%) of them are from rural areas. The majority of (60%) of respondents were single, and others were in a relationship. During the study period (70.9%) of the respondents were living in a hostel, (15.6%) were living in a rented house, and (13.5%) were living in another relative house. Most of the respondents have knowledge about STIs, but there are still misconceptions and their practice remained quite low. Keywords: STDs, Sexually active adolescents, Females, Sexual transmission infection, Health institutes.
THEORETICAL INVESTIGATION OF PERFORMANCE OF VAPOR COMPRESSION COOLING CYCLE FOR DME, R125, R134A, R143A, R152A, AND R32 REFRIGERANTS AND THEIR MIXTURES
Authors: YOLCAN Oguz Ozan
Published: May 2023

In this study, the performances of refrigerant mixtures in ideal vapor compression refrigeration cycles were investigated theoretically. By choosing six different refrigerants as dimethyl ether (DME), R125, R134a, R143a, R152a, and R32, eleven different refrigerant mixtures were handled. Each mixture's vapor compression refrigeration cycle performances were evaluated according to three different condenser outlet temperatures and nine different mass fractions (90%/10% to 10%/90%). To examine the thermodynamic performance of refrigerant mixtures, constant evaporator outlet temperature (-10 oC) and different constant condenser outlet temperatures (20 oC, 25 oC, and 30 oC) were determined. According to the evaluated refrigerant mixtures, the COPR values of the refrigerant mixtures containing DME were calculated as the highest among all the mixtures. In the mixtures containing DME, it was observed that the COPR values decreased as the mass percentage of DME decreased. The COPR values are calculated in the range of 3.66-5.70 for the R134a/R32 mixture, 3.82-5.81 for the R134a/R143a mixture, 3.97-5.99 for the R143a/R32 mixture, 3.83-5.83 for the R125/R143a mixture, 3.86-5.98 for the R125/R32 mixture, 4.34-6.24 for R134a/R152a mixture, 3.78-5.81 for R143a/R152a mixture, 3.57-5.55 for R152a/R32 mixture, 3.40-6.28 for DME/R125 mixture, 4.34-6.27 for DME/R134a mixture and 3.59-5.82 for the DME/R32 mixture.
When the pure forms and mixtures of the refrigerants discussed in the study are compared, it is seen that the pure DME and R32 gases are slightly more performant than the gas mixtures examined. The R125 gas mixture shows a higher performance than the pure R125 gas, and the R134a and R143a mixtures show slightly higher performance than the pure gas forms. Finally, the specific energies of pure refrigerants and refrigerant mixtures were calculated within the scope of the study. DME has the highest specific energy among pure refrigerants, while DME/R32 mixture has the highest specific energy among refrigerant mixtures.
La Orden de San Juan en el Reino de Toledo durante los siglos XII y XIII: bienes patrimoniales y encomiendas
Authors: Barquero Goñi Carlos
Published: May 2023

El reino de Toledo fue una parte de Castilla desde el siglo XI. Constituyó un territorio de frontera con el Islam durante los siglos XII y XIII. En consecuencia, la monarquía castellana instaló a diversas Órdenes Militares para defender al reino de Toledo de los musulmanes durante aquella época. Una de ellas fue la orden internacional de San Juan u Orden del Hospital. De hecho, esta Orden tenía una provincia o priorato en Castilla desde el siglo XII. Sabemos que tanto reyes como nobles castellanos donaron entonces numerosas propiedades a los hospitalarios en el reino de Toledo. En efecto, la Orden obtuvo aquí su mayor señorío de la Corona de Castilla. En consecuencia, los hospitalarios tuvieron que implantar una importante organización a nivel local. Conocemos que instalaron muchas encomiendas o bailías en el reino de Toledo. En concreto, hubo veintiuna encomiendas de la Orden de San Juan aquí durante los siglos XII y XIII.
Los escribanos públicos de Segovia a través de la documentación notarial del monasterio de Santa María de Párraces (1284-1500)
Authors: Puñal Fernández Tomás
Published: May 2023

El presente trabajo analiza desde el método diplomático el fondo notarial de uno de los monasterios más significativos de la tierra de Segovia para conocer cómo fue la actuación de los escribanos que dieron testimonio escrito de los diversos actos jurídicos entre los siglos XIII y XV, relativos a la formación y protección de su patrimonio económico y jurisdicción eclesiástica dentro las estructuras feudales del régimen señorial. A este fin, se estudian los distintos escribanos en función de los poderes a los que representan y el carácter formal de sus documentos, todo ello en consonancia con las relaciones de poder entre el mundo civil y el eclesiástico de las que dichos escribanos fueron una pieza representativa y fundamental.
«Que aunque quieren ser buenos cristianos no los dejan»: el clero y los moriscos del reino de Granada (1501-1526)
Authors: Rayo Muñoz Gema
Published: May 2023

Este artículo analiza la idoneidad del clero del reino de Granada y sus relaciones con los feligreses moriscos. Tras las conversiones forzosas, la corona desarrolló una política religiosa que no obtuvo resultados y que la llevó a promulgar una serie de cédulas entre 1511 y 1514. El objetivo de este trabajo es determinar, a través de documentación inédita conservada en el Archivo General de Simancas, si las medidas adoptadas entre estos años lograron algún resultado en términos de residencia, simonía y actitud del bajo clero hacia los cristianos nuevos.
Textos monetarios del siglo XIV: el fuero de Huete y el documento de los «Treze»
Authors: Oliva Manso Gonzalo
Published: May 2023

Los cambios producidos en el sistema monetario de Castilla desde 1268 causaron continuos problemas a sus habitantes a la hora de valorar las cantidades que aparecían en sus documentos legales. Para resolver el problema apareció un breve texto conservado como un anexo del Fuero Real publicado en 1781 y aunque presenta algunos fallos, sirvió como referencia a una serie de tratados que lo fueron completando con otros materiales. Paralelamente recibió una estructura más elaborada hasta alcanzar el texto definitivo contenido en el fuero de Huete. En las páginas siguientes se estudia su contenido, comprobándose su exacto paralelismo con la historia monetaria hasta ahora conocida, y se ofrece un estema que refleje las pautas de su desarrollo formativo.
Sancha Alfonso, religiosa del monasterio de Santa Eufemia de Cozuelos (siglo XIII): filiación, matrimonio, propiedades y expiración
Authors: Sánchez-Migallón López-Villanueva Pedro
Published: May 2023

El presente artículo ofrece un análisis y revisión de los principales aspectos biográficos de Sancha Alfonso, hija de Alfonso IX de León y Teresa Gil de Soverosa, y religiosa del monasterio de Santa Eufemia de Cozuelos (Palencia): filiación, matrimonio, propiedades y expiración. Además, expone las opiniones de los principales autores que han tratado su figura. Su metodología se basa en el examen de la fuentes documentales y bibliográficas existentes al respecto, así como en el empleo auxiliar de la geografía y la sigilografía. La finalidad es la de complementar las investigaciones realizadas hasta el momento sobre ella, así como la de favorecer el desarrollo de los estudios prosopográficos dentro del ámbito de las Órdenes Militares, en concreto, de la Orden de Santiago.
Modified Jackknife Ridge Estimator for Beta Regression Model With Application to Chemical Data
Authors: Algamal Zakariya Yahya , Abonazel Mohamed R. , Lukman Adewale F.
Published: May 2023

The linear regression model is not applicable when the response variable's value comes in percentages, proportions, and rates, which are restricted to the interval (0, 1). In this situation, we applied the beta regression model (BRM) popularly used to model chemical, environmental and biological data.  The parameters in the model are often estimated using the conventional method of maximum likelihood. However, this estimator is unreliable and inefficient when the explanatory variables are linearly correlated- a condition known as multicollinearity. Thus, we developed the Jackknife Beta ridge and the modified Jackknife Beta ridge estimator to estimate the regression coefficient when multicollinearity exists efficiently. The properties of the new estimators were derived. We compared the estimator's performance with the existing estimators theoretically using the mean squared error criterion. Furthermore, we conducted a simulation study and chemical data to evaluate the new estimators’ performance. The theoretical comparison, simulation, and real-life application results established the dominance of the proposed methods.
Severity Classification for COVID-19 Infections based on Lasso-Logistic Regression Model
Authors: Arif Zainab Hussein , Cengiz Korhan
Published: May 2023

The tremendous growth of the Covid19 epidemic in recent months is devastatingly affecting human civilization. Many different biomarkers are being studied to monitor the patient's health. This might mask the symptoms of various diseases, making it more challenging for a doctor to make a correct diagnosis or prognosis. Therefore, this study aimed to create several classes of prediction methods that can handle situations of varying severity (severe, moderate, and mild). Using machine learning, a Lasso-logistic regression model is developed. To create the Covid-19 clinical dataset, researchers enlisted the help of 78 patients from the Azizia main hospital sector, the Wasit Health Directorate, and the Ministry of Health. The results show that the proposed method is generally accurate to 85.9%. Deaths have been reduced thanks to the established prediction method that enables early detection of patients across three severity levels.
On The Product and Ratio of Pareto and Erlang Random Variables
Authors: Obeid Noura
Published: May 2023

The distributions of products and ratios of random variables are of interest in many areas of the sciences.In this paper, we find analytically the probability distributions of the product XY and the ratio X/Y ,when X and Y are two independent random variables following Pareto and Erlang distributions, respectively
Fibrodysplasia Ossificans Progressiva: Molecular Mechanism, Drug Development and Current Clinical Trials
Authors:   Mission San Jose High School, 41717 Palm Ave, Fremont, CA94539, USA, Xu Annie
Published: May 2023

Fibrodysplasia ossificans progressiva (FOP) is a rare genetic human disease characterized by abnormal bone formation in muscle and soft tissues of the patient, due to dysregulated activity of the bone morphogenetic protein (BMP) signaling. Activin A receptor type I (ACVR1), also known as Activin-like kinase 2 (ALK2), is a key BMP type I receptor for the normal BMP signaling transduction. The heterozygous missense mutations in ALK2 are the root cause of FOP, and ALK2R206H accounts for approximately 97% of all FOP cases. Cumulative studies have shown that Activin A, which normally activates TGF - β signaling, can induce the BMP signaling via ALK2 mutated receptor in FOP. In the past decade, multiple therapeutical strategies have been developed and several potential drugs are under clinical trials for FOP now. This article specifically focuses on the recent progress in understanding the molecular mechanism, potential drug development and the clinical trials for FOP treatment.
PKM Panti Asuhan Nurul Amal
Authors: Rahmat Rezqiqah Aulia , Pannyiwi Rahmat , Syafri Muhammad , M Sahdan
Published: May 2023

Bakti Sosial dengan kunjungan ke panti asuhan merupakan salah satu kegiatan wujud dari rasa kemanusiaan antara sesama manusia. Bakti Sosial merupakan suatu kegiatan dimana dengan adanya kegiatan ini kita dapat merapatkan hubungan kekerabatan kita. Bakti Sosial diadakan dengan tujuan-tujuan tertentu untuk mewujudkan rasa cinta kasih, rasa saling menolong, dan rasa saling peduli kepada masyarakat. Pendampingan tersebut dapat berupa kegiatan Makan bersama, Bernyanyi bersama, Berdoa bersama, Berbincang-bincang dengan para anak - anak yang menetap di Panti Asuhan. Hasil yang kami peroleh dari kegiatan ini adalah kami mendapatkan pengalaman berharga saat mendampingi anak anak kita yang tinggal di Panti Asuhan. Kami berkesempatan mendengarkan kisah dari mereka yang tentunya mendidik dan berarti bagi kehidupan kami di masa yang akan datang. Dari kegiatan ini pula kami disadarkan pada kenyataan bahwa anak - anak merasa kesepian dan membutuhkan perhatian lebih dari pengunjung yang datang.
Penyuluhan Kesehatan Tentang Pengetahuan Ibu Terhadap Penyakit Diare Pada Balita
Authors: Ekawati Nur , B Muslimin , Serli Serli , Arda Darmi , Syam Rosida , Andi Latif Sarifudin
Published: May 2023

Diare merupakan suatu keadaan pengeluaran tinja yang tidak normal atau tidak seperti biasanya. Perubahan yang terjadi berupa perubahan peningkatan volume, keenceran, dan frekuensi dengan atau tanpa lendir darah, seperti lebih dari 3 kali/hari dan pada neonatus lebih dari 4 kali/hari. Tujuan PKM ini adalah meningkatkan pengetahuan dan kesadaran masyarakat untuk menjaga dan memelihara kesehatan diri dan lingkungan supaya terhindar dari penyakit diare. Berdasarkan hasil pengabdian didapatkan bahwa ada peningkatan pengetahuan tentang diare pada balita dan penanganannya. Hal tersebut terjadi karena dilakukan pendidikan kesehatan yang diberikan. Dari hasil setelah pendidikan kesehatan meningkat/ lebih tinggi dibanding sebelum penyuluhan.
Reforming Teacher Education for Inclusion in Developing Countries in the Asia Pacific Region
Authors:   Faculty of Education, Monash University, Victoria, Australia, Sharma Umesh , Forlin Chris ,   Faculty of Education and Human Development, Hong Kong Institute of Education, Hong Kong, China, Deppeler Joanne ,   Faculty of Education, Monash University, Victoria, Australia, Guang-xue Yang ,   Faculty of Preschool & Special Education, East China Normal University, Shanghai, China
Published: May 2023

A number of Asian Pacific countries have ratified the UN Conventions on the Rights of People with Disabilities and have identified an urgent need to include children with special educational needs in regular school programs. Successful implementation of such a policy reform requires significant changes in the way education is provided to all students, but most importantly depends upon how adequately the teachers and related professionals are prepared to implement the reform. This paper reviews research from 13 Asian Pacific countries, undertaken in the last five years, to address two questions. First it reports on the issues, challenges, and proposals related to inclusive education in these countries. Second the review reports on how each region has progressed towards implementing the Millennium Development Goals with particular emphasis on how teacher education has or has not responded to this. The review concludes that a lack of well thought out policy, few resources, and limited understanding of inclusion seems widespread in the Asia-Pacific region. As yet special education and related service expertise and teacher education for inclusion, is not in place to support teachers to work inclusively.
Changing Paradigms and Future Directions for Implementing Inclusive Education in Developing Countries
Authors:   Department of Learning Science, Hiroshima University/ Hong Kong Institute of Education, Forlin Chris
Published: May 2023

This paper reviews how the international trend to adopting an inclusive approach to education is impacting upon developing countries. Like all regions, developing countries are unique in their requirements. They thus require policy and practices that not only adopt the international Conventions but that also reflect their uniqueness and provide a methodology for implementing inclusion that is regionally and locally effective. Conflicting issues of providing equity while maintaining greater accountability are especially challenging for developing countries with their enormous diversity of students, support, access, and options. The impact on teachers, the role of the principal, competing educational systems, and a reluctance to move away from firmly entrenched pedagogies and curricula also influence the development of inclusion. An examination of future directions for inclusive education considers how developing countries might respond to these challenges to advance an inclusive educational approach that ensures better equity and opportunity for all learners.
General Education Teachers’ Perceived Self-Efficacy in Teaching Students with Disabilities in Oman
Authors:   Madison Metropolitan School District, Wisconsin, USA, Haj Hussien Jalal , Al-Qaryouti Ibrahim ,   College of Education, Sultan Qaboos University, Sultanate Oman
Published: May 2023

The objective of this study was to determine general education teachers’ level of self-efficacy in teaching inclusive classrooms and to investigate whether general education teachers’ level of self-efficacy vary according to the domain of knowledge and skills. In addition, the current study examined the relationship between teachers’ gender, school level taught, teaching experience and their self-efficacy. Finally, this study explored the relationship between general education teachers’ self-efficacy and their attitudes toward inclusion. Seven hundred three general education teachers participated in this study. The mean scores of the teachers on the self-efficacy domains suggest that they had high levels of perceived self-efficacy in classroom management, moderate levels in collaboration and assessment, and low levels in special education. The findings also indicated that the perception of general education teachers as to their level of self-efficacy varied significantly according the domain of knowledge and skills. The findings also revealed that male teachers reported significantly higher levels of self-efficacy than female teachers. Moreover, the findings indicate that teachers’ teaching experience and school level taught had a significant relationship with their self-efficacies in some of the domains. Finally, the results showed significant positive correlations between teacher’s self-efficacy and their attitudes towards inclusion.
BRAC Primary School Teachers’ Teaching-efficacy, Attitude, Sentiment and Concern towards Inclusion of Children with Disabilities in Regular Classrooms in Bangladesh
Authors:   Deputy Manager, Social Innovation Lab, BRAC, Dhaka, Bangladesh, Tasnuba Tanjilut , Tsokova Diana ,   Senior Lecturer in Psychology of Special Needs in Primary Education, UCL Institute of Education, London, United Kingdom
Published: May 2023

BRAC (Bangladesh Rural Advancement Committee) is the largest non-governmental organisation in Bangladesh that is involved in the provision of education to 674,229 children, including 25,637 children with disabilities (BEP, 2014). The aim of the research reported in this paper is to explore BRAC Primary School teachers’ teaching efficacy, attitude, sentiment and concern towards the inclusion of children with disabilities in regular classrooms, in order to inform future efforts and developments with inclusive education. 400 randomly selected BRAC primary school teachers from 48 districts of 7 regions of Bangladesh participated in this research. The Teacher Efficacy for Inclusive Practice (TEIP) and Sentiments, Attitudes, Concerns regarding Inclusive Education-Revised (SACIE-R) (Sharma, Loreman, &Forlin, 2012; Forlin, Loreman, & Sharma, 2011) scales were utilities in this study along with a demographic questionnaire. The results show that BRAC teachers have relatively high level of overall teaching efficacy, moderately positive attitude and generally low concern towards inclusion of children with disabilities. The study found no significant relationship between the background and demographic variables used for this study and BRAC teachers’ teaching efficacy and attitude. The study also revealed a significant difference in BRAC teachers’ concern based on students’ disability type, and a significant positive relationship between teaching efficacy and attitude and concern. Based on the findings, the study suggests further collaboration between government and BRAC to create the conditions for higher teacher efficacy and positive attitude towards inclusion of children with disabilities, providing school support, resources, and extensive training opportunities.