bluuebunny/crossref_metadata_2025 huggingface dataset:
Accumulation of aggregated alpha-synuclein in neural tissue structures in neurodegenerative diseases
Authors: Salkov V. N. , Voronkov D. N.
Published: January 2024

A critical analysis of the literature on the structure and properties of alpha-synuclein under physiological and pathological conditions is presented, when the conformation of this protein changes, which contributes to its aggregation and changes in localization features in brain structures in such neurodegenerative diseases as Parkinson’s disease, dementia with Lewy bodies, multiple systemic atrophy and Alzheimer’s disease. It has been shown that the toxic effect of conformationally altered alpha-synuclein can indirectly affect the functions of neurons due to its interaction with neuroglial cells, primarily microglia and astrocytes, and can also modulate the aggregation and expression of other proteins that are functionally important for the development of neurodegeneration. Further study of the mechanisms of interaction of conformationally altered alphasynuclein with other proteins and clarification of the relationship between its accumulation in brain structures and neuronal dysfunction remains relevant for modern neurology. Literature search was carried out in the “PubMed” and “eLIBRARY” databases.
Cytotoxic effect of the VVGMCSF-Lact oncolytic virus against 3D cultures of human glioblastoma cells U-87 MG
Authors: Dymova M. A. , Shnaider T. A. , Chechetkina S. A. , Petrov G. O. , Malysheva D. O. , Drokov D. V. , Ageenko A. B. , Vasileva N. S. , Richter V. A. , Kuligina E. V.
Published: January 2024

Background. One of the promising methods of treating tumors is virotherapy, which is based on direct lysis of cancer cells by a virus and a virus-mediated antitumor immune response of the body. For the recombinant vaccinia virus strain VVGMCSF-Lact, producing human GMCSF and the oncotoxic protein lactaptin, cytotoxic and antitumor effects were shown in experiments in vitro and in vivo, respectively, when using adhesive cultures of U-87 MG human glioblastoma cells. 3D cultures are a more relevant tumor model than adhesive models, as they more fully reflect the realistic scenario of cancer development, as well as the response of the tumor to anticancer therapy.

The aim. To evaluate the cytotoxic effect of the oncolytic virus VV-GMCSF-Lact against 3D cultures of human glioblastoma U-87 MG.

Materials and methods. The following methods were used in the work: cultivation of 3D cell cultures, cytofluorometry, microscopic analysis, virus titration, statistical analysis.

Results. U-87 MG cells were transduced with a lentiviral vector carrying the GFP reporter gene. The cytotoxicity of the VV-GMCSF-Lact virus (IC50) against the studied cells was 0.024 PFU/cell. U-87 MG cells were cultured under conditions for the formation of 3D structures. Microscopic analysis showed the oncolytic effect of the virus on the cells of 3D cultures as early as 24 hours after the start of incubation. Flow cytometry showed an increase in the granularity of glioblastoma cells under the action of the virus, which indicates active replication of the virus in the cells. The virus titer was 0.44 PFU/cell.

Conclusions. The recombinant VV-GMCSF-Lact virus has a cytotoxic effect on 3D human glioblastoma U-87 MG cell cultures and actively replicates in them. In the future, to test the oncolytic effect of VV-GMCSF-Lact, it is planned to use not only 3D human glioblastoma cultures, but also cerebral organelles obtained in the process of cocultivation of glioblastoma cells and induced human pluripotent cells.
Attitude and awareness of Indian parents from Kerala state towards children’s vaccination at the COVID-19 pandemic background
Authors: Aaromal Sureshkumar Ajitha , Novikova E. A. , Abhiramy Suprasannan , Manu Krishna Maniyan Girija , Vanyarkinа A. S. , Moskaleva E. V. , Kazantseva E. D. , Petrova A. G. , Rychkova L. V.
Published: January 2024

Background. Vaccination coverage of children in India is not sufficient since the COVID-19 pandemic (less than 90 %). This may lead to low adherence of parents to children’s vaccination.

The aim. To study parental attitudes and awareness towards children vaccination programs in India at the COVID-19 pandemic background.

Methods. Two hundred and fourteen participants from Kerala state (India) took part in the descriptive cross-sectional study via survey method. The survey was prepared with Google form according the principles of anonymity.

Results. Indian parents demonstrated good adherence towards children’s vaccination, 98.6 % (95% confidence interval (CI): 95.9–99.5) of them vaccinated their child, and if vaccination appointment had to be rescheduled 84.6 % (95% CI: 79.1–88.8) of  them vaccinated children after. Most of Indians (68.7  %; 95%  CI: 62.1–74.5) preferred to vaccinate children in state clinics, however, 28.5 % (95% CI: 22.8–34.8) chose private clinics. Information about diseases that vaccines can prevent, vaccine safety, and side effects 47.2 % (95% CI: 40.6–53.8) of parents got from public pediatricians, 50.9 % (95% CI: 44.2–57.5) – from private pediatricians, and 10.3 % (95% CI: 6.8–15.0) – from complementary and alternative medicine practitioners. Over 80 % of Indians were informed about vaccination through mass media (83.6%; 95% CI: 78.1–87.9). Indian parents showed low awareness about vaccination, because 63.1 % (95% CI: 56.4–69.2) of parents wanted to know more about vaccination. Moreover, before vaccination 21.5 % (95% CI: 16.5–27.4) of them were not informed by a doctor about health benefits and possible risks for their children.

Conclusion. In the COVID-19 pandemic Indian parents showed good attitude towards vaccination and low awareness in vaccination questions.
Assessment of the actual nutrition of rural adolescents of the Irkutsk region because of revision of the norms of physiological needs for energy and nutrients
Authors: Rychkova L. V. , Pogodina A. V. , Astakhova T. A. , Lebedeva L. N.
Published: January 2024

Background. The rational nutrition of the child population is given great medical importance as a factor in preserving the health and development of the child. A complete and balanced diet in terms of the content of basic nutrients ensures the normal growth and development of the child’s body.

The aim. To analyze of the actual nutrition of adolescents living in rural areas of the Irkutsk region.

Materials and methods. The study involved 69 rural adolescents aged 11–17 years (34 boys, 35 girls). The actual nutrition was studied by the method of 24-hour nutrition reproduction. The energy value of the diet was determined, the nature of the provision of the diet with basic macro- and microelements was studied. The obtained values were compared with the norms of  physiological needs for energy and nutrients in 2008 and 2021.

Results. The analysis of actual nutrition revealed deviations from the principles of  healthy nutrition: insufficient energy value of the diet, deficiency of proteins and  fats. The diet of  adolescents was characterized by an insufficient content of the main groups of macro- and micronutrients – vitamins A, C and D, essential trace elements, and a deficiency of dietary fiber. The diet of adolescents was characterized by increased sodium intake. The calculated ratio of proteins, fats, carbohydrates indicated a carbohydrate type of diet.

Conclusion. Despite the great attention to the problem of balanced nutrition of adolescents, the question of the impact of nutrition on the health of a teenager, considering the regional factor, remains open. Recommendations for the development of a regional program for the organization of proper nutrition for school-age children are of great practical importance.
Features of drug-drug interactions rivaroxaban and calcium channel blockers depending on the ABCB1 genotype (rs1045642 and rs4148738) in patients 80 years of age and older with non-valvular atrial fibrillation
Authors: Sychev D. A. , Mirzaev K. B. , Cherniaeva M. S. , Shakhgildyan N. V. , Abdullaev Sh. P. , Denisenko N. P. , Sozaeva Zh. A. , Kachanova A. A. , Shastina V. R. , Gorbatenkova S. V.
Published: January 2024

Background. The use of P-glycoprotein (P-gp) inhibitors and carriage of certain ABCB1 polymorphisms can lead to increased concentrations of rivaroxaban and the development of bleeding.

The aim of the study. To study the features of drug-drug interactions (DDI) of rivaroxaban in patients over 80 years of age with non-valvular atrial fibrillation depending on the ABCB1 genotype (rs1045642 and rs4148738) using the example of verapamil (P-gp inhibitor) and amlodipine.

Materials and methods. One hundred and twenty-eight patients were examined (median age – 87.5 [83–90] years). Genotyping, determination of the minimum equilibrium concentration of rivaroxaban (Cmin, ss), with standardization for the daily dose (Cmin, ss/D), coagulogram and analysis of medical documentation for the presence of clinically relevant non-major bleeding (CRNM) were carried out. Analysis of CRNM was performed depending on the ABCB1 genotype.

Results. The use of rivaroxaban with verapamil in comparison with patients not taking calcium channel blockers (CCBs) leads to high Cmin, ss values in the CC genotype (rs1045642, rs4148738); Сmin, ss and Сmin, ss/D in the CT genotype (rs1045642); prothrombin time in the CC genotype (rs1045642), more frequent occurrence of CRNM in the TT  genotype (rs1045642, rs4148738). In  comparison with patients taking amlodipine, it leads to high Cmin, ss values in the CT genotype (rs1045642), a more frequent occurrence of CRNM in the TT genotype (rs1045642, rs4148738). The use of rivaroxaban with amlodipine in comparison with patients not taking CCBs leads to high Cmin, ss and Cmin, ss/D values in the CC genotype (rs1045642) (p < 0.017).

Conclusion. The use of verapamil with rivaroxaban in ABCB1 TT carriers (rs4148738 and rs4148738) leads to the development of CRNM in 75 and 78 % of cases, respectively. In  patients taking rivaroxaban, it is advisable to test the ABCB1 genotype (rs4148738 and rs4148738) before adding a P-gp inhibitor to therapy.
Susceptibility of some Enterobacteriaceae isolated from 4 different aquatic environments in DR Congo (Central Africa), to Amoxicillin/Clavulanic acid and some 3rd generation Cephalosporins
Authors: Mwanzo Wavindu  , Edith B. Mouafo Tamnou  , Ildephonse Soly Kamwira  , Rosanne M. Ngome  , Paul Alain Nana  , Geneviève Bricheux  , Maximilienne A. Nyegue  , Télesphore Sime-Ngando  , Moïse Nola
Published: January 2024

Little is known about the variation of the antibiotic susceptibility of different bacterial strains of the same cells species, isolated from different aquatic environments. The present study aims to evaluate the susceptibility towards some 3rd generation cephalosporins (Ceftriaxon, Ceftazidim and Cefotaxim) and Amoxicillin/Clavulanic acid, of Enterobacteriaceae strains isolated from groundwater, stream, hospital wastewater and slaughterhouse wastewater. Enterobacteria species were isolated on Mac Conkey agar, then identified using enzymatic and MALDI-TOF MS system. The antimicrobial susceptibility was carried out using the disk diffusion method. The antibiotic minimum inhibitory concentrations (MICs) were carried using the VITEK®2 system. Bacterial species mostly identified were Klebsiella pneumoniae, Escherichia coli, Salmonella typhi and Ewingelia americana. The antibiotic inhibition diameters and the MICs varied depending on the antibiotics, bacterial species and type of aquatic environment hosting the microorganism. Relatively lower MICs were recorded with Cefotaxim against different bacteria in slaughterhouse wastewater, in river water and in well water. Antibiotic resistance was noted with all strains from hospital wastewater. Significant differences (P˂0.05) amongst antibiotic inhibition diameter was noted for K. pneumoniae and S. typhi in most cases. The relative variations in the action mechanisms amongst antibiotics and the intrinsic defense potential of each bacterial strain, as well as the potential influence of the physicochemical properties of each water medium, could partly be at the origin of the relative differences observed at the phenotypic level. It seems necessary to explore the diversity, similarities and differences amongst antibiotic resistance genes in these different types of aquatic biotopes.
Investigating waste disposal methods and public perceptions of government-supervised contractors in selected Port Harcourt residential communities
Authors: Tamunoikuronibo Dawaye Ikiriko  , Anthony Dornubari Enwin  , Simeipiri Wenike Johnbull
Published: January 2024

This research investigates waste disposal methods and the public's perceptions of government-supervised contractors in selected residential communities within Port Harcourt, Nigeria. The study focuses on the Public Private Partnership (PPP) approach implemented by the Rivers State Government through the establishment of the Rivers State Waste Management Agency (RIWAMA). It explores various dimensions of waste management, encompassing practices of refuse disposal, public attitudes, waste segregation, household waste disposal behaviours, community satisfaction levels, and community involvement. The study unveils a spectrum of refuse disposal methods utilized by households, emphasizing their regulatory and environmental implications. Public perceptions of the waste management system exhibit considerable diversity across different aspects, underscoring the necessity of addressing concerns and enhancing overall public satisfaction. Furthermore, the research highlights a lack of waste segregation practices among residents and service providers, stressing the importance of promoting waste segregation for recycling and environmental sustainability. Private waste handlers are predominantly relied upon by residents for household waste disposal, necessitating vigilant regulation and environmental considerations. In light of these findings, recommendations are put forth, including bolstered regulation, increased infrastructure investment, educational campaigns, advocacy for recycling, and enhancements in service quality. These recommendations aim to establish a more efficient and sustainable waste management system in Port Harcourt, aligning with global sustainability objectives and environmental preservation.
Telecom data analytics: Informed decision-making: A review across Africa and the USA
Authors: Oluwaseun Augustine Lottu  , Chinedu Alex Ezeigweneme  , Temidayo Olorunsogo  , Ayodeji Adegbola
Published: January 2024

Telecom data analytics has emerged as a pivotal tool for transforming raw data into actionable insights, empowering telecom operators to make informed decisions and enhance the overall efficiency of their networks. This abstract provides an overview of the comprehensive review that explores the landscape of telecom data analytics in both Africa and the USA. The review delves into the diverse strategies, challenges, and opportunities associated with telecom data analytics in these regions. It examines how advanced analytics techniques, including machine learning and artificial intelligence, are being leveraged to extract valuable insights from vast datasets. The comparative analysis highlights contextual differences in regulatory environments, infrastructure development, and technological landscapes that influence the adoption and implementation of telecom data analytics. In Africa, where the telecom landscape is dynamic and diverse, the review explores how data analytics is playing a crucial role in addressing connectivity challenges, optimizing network performance, and expanding telecommunications services. It also considers the impact of regulatory frameworks and investment climates on the deployment of data analytics solutions. In the USA, a mature telecom market with high technological adoption, the review investigates how data analytics is shaping decision-making processes, improving customer experiences, and contributing to the development of innovative services. It delves into the regulatory landscape, market dynamics, and the role of data analytics in maintaining a competitive edge. Throughout the review, the focus is on identifying best practices, lessons learned, and cross-regional insights that can inform the future trajectory of telecom data analytics. The abstract encapsulates the broader themes of the review, offering a glimpse into the critical role played by data analytics in shaping the telecom industry across Africa and the USA.
Formulation and development of herbal facewash using Beal leaves: Aegle marmelos
Authors: Rutuja S Rokade  , Sakshi R Vidhate  , Disha S Kale  , Shravan. J. Somani
Published: January 2024

In this study, herbal anti-acne face wash gels were prepared using polymers Carbopol and extract of aegle marmelos (beal patra), which show the antibacterial property and are widely used in modern herbal medicine. Results showed that the gels were non-irritating, stable, and possess anti-acne activity. Acne is a common skin problem that 85% of teenagers face today. Herbal drugs have been used for many years, not only in Asian countries but also worldwide for social well-being. Herbal formulations have rising demand in the global market. This study demonstrated the stability of herbal Gel, which is now regarded as an efficient herbal acne treatment formulation. A number of characteristics, including color, appearance, consistency, pH, and foamability, were assessed for the prepared formulation. Because natural remedies are safer and have fewer side effects than synthetic ones, they are more widely accepted.The demand for herbal formulations is rising on the international scene. The creation and assessment of a herbal anti-acne cleanser with aqueous bael leaf (Aegle marmelos) extracts are the subjects of this study. Despite the fact that there are many topical herbal remedies for acne on the market, the plant has good antibacterial, antioxidant, and anti-inflammatory properties according to published research.
The impact of prolactin and vitamin D levels as a prognostic markers of female hair loss
Authors: Areej Shakeer Jassum  , Wafaa Ayad Al-Nuaimy  , Nuha. M. Mousa  , Hawraa Aqeel Abdul Munem  , Sheereehan A.M. Albyati
Published: January 2024

A limited number of case reports seem to point the interaction between thinning hair and a vitamin D deficiency. This research looked at the relationship between prolactin levels and vitamin D levels in women with hair loss. The anterior pituitary gland secretes a polypeptide hormone called prolactin, which has a variety of biological effects, including the capacity to encourage growth and have a proliferative influence on human keratinocytes. Calcium homeostasis is affected by this hormone as a result of deficiency in vitamin D. This study was conducted on 75 patients during the period from November 2019 to March 2021. Serum prolactin and vitamin D levels were measured by chemiluminescence through an immunoassay (automated) and fluorescence Immunoassay (FIA) for vitamin D measurement. Serum prolactin levels were significantly elevated in pregnant women with hair loss compared with healthy controls. Vitamin D and serum prolactin levels had a remarkable positive correlation (r = 0.661, P 0.005). Prolactin and vit. D may play a part in hair loss in women.
The fulcrum of the human heart (Cardiac fulcrum)
Authors: Jorge Trainini  , Mario Wernicke  , Mario Beraudo  , Alejandro Trainini
Published: January 2024

Introduction: The functional anatomy of the myocardium allows envisioning that it initiates and ends at the origin of the great vessels. In our research, we have always considered that it should have a point of attachment to allow its helical rotation to fulfill the fundamental movements of shortening-torsion (systole) and lengthening-detorsion (suction), which once found, was called the cardiac fulcrum. Material and Methods: A total of 31 hearts, arising from the morgue and slaughterhouse were used: 17 corresponded to bovids and 14 were human. Anatomical and histological studies were performed. The heart was fixed in 10% buffered formalin. Hematoxylin-eosin, Masson’s trichrome staining technique and 4-micron sections were used for the histological study, and 10 % formalin was used as buffer. Results: The anatomical investigations have revealed that all the hearts (bovids and humans) have a myocardial support whose histological structure in the analyzed specimens presents with an osseous or chondroid-tendinous character. In this structure, that we have call cardiac fulcrum, are inserted the myocardial fibers at the origin and end of the band, which correspond to the continuous myocardium coiled as a helix. Conclusion: This description of the fulcrum would end the problem of lack of support of the myocardium to fulfill its function of suction/ejection.
Pengetahuan dan Kesadaran Masyarakat Tentang Kebutuhan Vaksin COVID-19 di Kabupaten Purworejo
Authors: Pravitasari Ines Ratni
Published: January 2024

COVID 19 is becoming a health problem today. Several efforts have been made by the government to prevent the spread of COVID-19, one of which is by vaccinating. The public response to be active in preventing the spread of COVID19 through vaccination has not been optimal. This activity was carried out with the aim of increasing public knowledge and awareness about the COVID-19 vaccine. The activity was attended by 14 people aged 18-60 years was carried out through exposure methods, questions, and answers, and the presence of pretests and posttests to assess community understanding. Based on the results of the evaluation of activities, it is known that all participants experienced increased knowledge about COVID-19 vaccination. The result of the evaluation of public awareness about the COVID-19 vaccine is that 57% of the public is willing to vaccinate. Given the large benefits of this activity, it is expected that the activities that have been carried out can be sustainable or continued by the public and related parties, so it can increase vaccination coverage to prevent the spread of COVID19 infection
The Overview of Child development During the Covid-19 Pandemic
Authors: Astutiek Dwi , Suhardiningsih AV Sri , Kusuma Damayanti , Listyowati Anies , Sardjono Sastro
Published: January 2024

During the Covid-19 pandemic, various activities to stimulate young children suddenly stopped due to the emergency condition of the Covid-19 outbreak, However, the stimulation of growth and development for young children was quite ongoing and obtained quite good results by implementing the Covid-19 health protocol. The aims of this study is to describe the growth and development of children during the Covid-19 pandemic. The research method used is qualitative research with a phenomenological approach. The data collected is by means of participants observation and in-depth interviews through FGDs. The research results obtained are that children's growth and development can be seen by monitoring in the form of anthropometric measurements at the puskesmas or public health centers, as well as passive monitoring of growth and development as seen from the KIA’s handbook to prevent mass crowds as an effort to prevent the transmission of Covid-19 . The result  in this study  found that most were on the growth line in the KIA’s Handbook, while for the level of nutritional intake there were still some children who were lacking in nutrition. Most of the development of gross and fine motor skills in children is in accordance with the KIA’s handbook, however there are a few whose development is not in line with the KIA’s handbook, this could be due to one of the contributing factors, namely nutritional intake. In addition there are 44.44% of children experienced the negative impact of the pandemic on their children's mental-emotional condition, 33.33% of their mental-emotional condition was not affected due to the covid 19 pandemic and 22.22% did not provide clear information. Some of contributing factors that hinder children's growth and development, one of which are nutritional status , the cooperation with health care facilities , and also the support from parents to use  educative indoor games and family recreation by implementing the Covid-19 health protocol.
Dampak Status Gizi Terhadap Kejadian Dismenorea
Authors: Fauzia Nura Suciati , Nuraida Ida , Raharsari Rezeki Tri , Putri Devia Lydia
Published: January 2024

Dysmenorrhea is menstrual cramps or menstrual pain that occurs mainly in the lower abdomen, but can radiate to the lower back, waist, pelvis, upper thighs, to the calves. Dysmenorrhea or cramps during menstruation also affect a person's quality of life, so that it can result in absenteeism from school, and can affect a person's nutritional status. Analyzing the relationship between nutritional status and the degree of dysmenorrhea in students. This research was conducted using a cross sectional approach. As an approach as many as 112 female respondents. The research sample size was calculated using the Slovin formula, so that a total sample of 53 students was obtained and was selected as a sample using simple random sampling technique. Univariate and bivariate analysis was used in this study using the chi-square test. The results of the study illustrate that the nutritional status is 0.015 so it can concluded that the nutritional status variable and the dysmenorrhea variable have a significant relationship. From the results of the study, it is illustrated that there is a relationship between nutritional status and the incidence of dysmenorrhea in students.
Analisis Unmodifiable dan Modifiable Risk Factors Terhadap Kejadian Hipertensi Pada Lansia di Puskesmas Tungoi
Authors: Ningsih Suci Rahayu , Fauzan Moh. Rizki
Published: January 2024

Hypertension is a degenerative disease usually referred to as the silent killer because sufferers do not know they have hypertension or do not know before checking their blood pressure.  The aim of this study was to analyze the non-modifiable and modifiable risk factors for hypertension.  The research design used by a Cross-Sectional Study .  The sample obtained in this study was 68 people taken by total sampling technique.  The analyzed to measure the relationship between unmodifiable and modifiable risk factor variables on the incidence of hypertension is the chi-square test. The results obtained for unmodifiable risk factors are age (0.002) and heredity (0.014) while the modifiable risk factors are stress (0.003), obesity (0.003), and sodium consumption (0.003) which are associated with the incidence of hypertension. Age and heredity factors cannot be avoided in the risk of hypertension so that hypertension can be controlled with modifiable risk factors such as-avoiding stress and doing lots of physical activity and sedentary behavior can be reduced.
Internalisasi Nilai Sabar dalam Kitab Tanbihul Ghafilin dalam Membentuk Karakter Santri di Pondok Pesantren Al-Amien Kediri
Authors: Rosyidah Jamilatur , Kadi Kadi
Published: January 2024

Abstract: This study aims to determine the method of internalizing the value of patience contained in the book Tanbihul Ghafilin. The book Tanbihul Ghafilin is studied at the Al-Amien Islamic Boarding School to shape the character of the students. Al-Amien boarding school is one of the boarding schools that upholds discipline. The use of a qualitative approach with this type of case study research resulted in the finding that students' understanding of the value of patience is contained in the Book of Tanbihul Ghafilin at the Al Amien Islamic Boarding School. Among them are students who are able to hold back from lust, withhold from things that are heavy, and withhold from things that are prohibited so as not to fall into the wrong things. This can be seen from the self-awareness of the students, both men and women, in obeying the rules of the Islamic boarding school. While the method of internalizing the value of patience in the book Tanbihul Ghafilin at the Al Amien Islamic Boarding School is the exemplary method, the habituation method, the punishment method. Some of the factors that influence the implementation of internalization of the value of patience include internal factors that come from the background of the students and external factors that come from teachers, parents, environment, facilities and infrastructure.
Abstrak: Penelitian ini bertujuan untuk mengetahui metode dalam menginternalisasikan nilai sabar yang terkandung dalam kitab Tanbihul Ghafilin. kitab Tanbihul Ghafilin dipelajari di Pondok Pesantern Al-Amien untuk membentuk karakter santri. Pondok pesantren Al-Amien merupakan salah satu pondok pesantren yang menjunjung tinggi tentang kedisiplinan. Penggunaan pendekatan menggunakan kualitatif dengan jenis penelitian studi kasus penelitian ini menghasilkan temuan bahwa pemahaman santri terhadap nilai sabar yang terkandung dalam kitab Tanbihul Ghafilin di Pondok Pesantren Al Amien. Diantaranya adalah santri mampu menahan dari nafsu, menahan dari hal-hal yang berat, dan menahan dari hal-hal yang dilarang supaya tidak terjerumus pada perkara yang salah. Hal ini dapat dilihat dari kesadaran diri para santri, baik laki-laki maupun perempuan, dalam menaati peraturan pondok, Sedangkan metode dalam menginternalisasikan nilai sabar dalam kitab Tanbihul Ghafilin di Pondok Pesantren Al Amien dengan metode keteladan, metode pembiasaan, metode hukuman. Beberapa faktor yang mempengaruhi dalam pelaksanaan Internalisasi nilai sabar meliputi faktor Internal yang berasal dari latar belakang santri dan faktor eksternal berasal dari guru, orang tua, lingkungan, sarana dan prasarana.
Analysis of students' critical thinking errrors in solving Algebra material problems
Authors: Mulyanto Bayu Hadi , Suastika I Ketut , Farida Nur
Published: January 2024

Tujuan penelitian ini adalah menganalisis kemampuan berpikir kritis peserta didik menyelesaikan soal aljabar menggunakan indikator gabungan berpikir kritis Facione dan tahapan Newman. Subjek terdiri dari 29 peserta didik dan hanya 6 peserta didik yang diwawancara serta di analisis berdasarkan kategori berpikir kritis tingkat tinggi, sedang, dan rendah. Pengumpulan data yang digunakan dalam penelitian ini meliputi tes, wawancara, dan catatan lapangan. Triangulasi metode digunakan untuk pengecekan keabsahan data. Hasil penelitian menunjukan bahwa pencapaian indikator gabungan kemampuan berpikir kritis dan tahapan Newman yang diperoleh dari peserta didik yang paling tinggi yaitu indikator menginterpretasi, membaca, dan memahami sebesar 89%. Sedangkan undikator yang paling rendah adalah menginferensi dan penulisan 46%.
The purpose of this study was to analyze students' critical thinking skills in solving algebraic problems using the combined indicators of Facione's critical thinking and Newman's stages. The subjects consisted of 29 students and only 6 students were interviewed and analyzed based on high, medium, and low critical thinking categories. The collection of data used in this study includes tests, interviews, and field notes. The triangulation method is used to check the validity of the data. The results of the study showed that the combined indicator achievement of critical thinking skills and Newman's stage was obtained from the highest students, namely interpretation, reading, and understanding indicators of 89%. While the lowest indicators are inference and writing 46%.
Kepemimpinan Sufistik Menurut Perspektif Al-Ghazali dan Ibnu Taimiyah
Authors: Rahmawati Desty , Abidah Sulistyaningrum Resti
Published: January 2024

Tujuan penelitian ini adalah untuk mengetahui kepemimpinan sufistik menurut perspektif Al Ghazali dan Ibnu Taimiyah. Penelitian ini menggunakan pendekatan kualitatif, yaitu mendeskripsikan dan menguraikan tentang  karakteristik kepemimpinan mnurut kedua tokoh sufi tersebut. Metode yang digunakan dalam pengumpulan data yaitu dengan studi kepustakaan. Hasil penelitian yang diperoleh yaitu terdapat benyak persamaan mengenai kepemimpinan Al Ghazali dengan Ibnu Taimiyah. Karakteristik pemimpin menurut keduanya memiliki persamaan yaitu amar ma’ruf nahi munkar, adil, dan berdasar pada Al Qur’an dan Hadits Sedangkan perbedaan kepemimpinan keduanya terletak pada pada proses pola pikir mereka. Al Ghazali yang merupakan seorang filsuf dan salah satu tokoh tasawuf menekankan pada akal dan batin yang dibuktikan bahwa terdapat 3 poin kepemimpinannya yang berisi intelektual, agama, dan akhlak. Sedangkan Ibnu Taimiyah menekankan pada hukum-hukum fiqh yang mengharuskan sebuah kepemimpinan itu mengikuti hukum Islam seeprti zakat, qurban, dan infaq.
Dampak Psikologis Pernikahan Dini di KUA Kecamatan Kejaksaan Kota Cirebon
Authors: Triadhari Imelda , Afridah Mumtaz , Salsabila Hana Haifah
Published: January 2024

Pernikahan atau perkawinan merupakan sesuatu yang sakral, maka dari itu harus dipersiapkan dengan benar baik secara fisik, finansial, dan spiritual. Oleh karena itu, tujuan penelitian ini adalah meneliti 1) penyebab perkawinan anak, 2) dampak psikologis perkawinan dini, dan 3) strategi mengatasi dampak negatif perkawinan dini terhadap anak dibawah umur. Metode penelitian ini menggunakan penelitian kualitatif yang dilakukan sejak 9 Maret hingga 7 April 2023 di KUA Kecamatan Kejaksaan Kota Cirebon. Penelitian dilakukan antara Maret dan April 2023 dan melibatkan berbagai responden terkait perkawinan anak atau pernikahan dini. Penelitian ini bertujuan untuk mengidentifikasi dampak pernikahan dini dari segi psikologis dengan fokus pada adaptasi individu, interaksi sosial, dan pola pengasuhan. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan tinjauan literatur dan studi kasus. Data dikumpulkan melalui wawancara, observasi, dan dokumentasi di Kantor Urusan Agama (KUA) Kecamatan Kejaksaan Kota Cirebon. Hasil penelitian menunjukkan bahwa pernikahan dini memiliki dampak negatif terhadap aspek psikologis, termasuk gangguan dalam adaptasi individu, interaksi sosial yang terbatas, dan pola pengasuhan yang tidak tepat. Pernikahan dini juga dapat menyebabkan neuritis depresif dan meningkatkan tingkat stres dan kecemasan. Dalam beberapa kasus, perkawinan anak yang terjadi pada usia muda dapat berakhir dengan perceraian. Dalam hal ini, sosialisasi dan program yang ditawarkan oleh KUA Kejaksaan memiliki peran penting dalam mengatasi pernikahan dini dan menciptakan keluarga yang harmonis.
Professional training of future specialists in the field of cadastre and registration of rights in graphic visualization of real estate objects
Authors: Fedotova Vera Sergeevna
Published: January 2024

The research aims to theoretically justify the use of 3D modeling and graphic design as a means of professional training of undergraduate students in the field of “Land management and cadastre” to solve practical tasks based on visualization of three-dimensional objects. The paper presents the stages of training future specialists in the field of cadastre and registration of rights in the basics of creating three-dimensional models in the professional sphere and their graphic design. The scientific novelty of the research lies in the original elaboration of the content of the discipline “Graphic (spatial) visualization of real estate objects” for the training of undergraduate students in the field of “Land management and cadastre” based on the integrated combination of studying the fundamentals of 3D modeling and graphic design as a tool for visualizing information and data. The author believes that this combination is necessitated by the need to educate students on the comprehensive solution to a professional task that requires creating a three-dimensional model and its design and represents the basis for understanding the essence of 3D cadastre. As a result of the research, examples of practice-oriented tasks within three interconnected modules of the discipline “Graphic (spatial) visualization of real estate objects” for undergraduate students in the field of land management and real estate cadastre are presented.
Professional linguistic personality of servicemen of the United States Armed Forces (based on the texts of American military bloggers)
Authors: Golubenko Elena Alexandrovna
Published: January 2024

The aim of the research is to determine the features of written colloquial speech of bloggers serving in the US Armed Forces in the system of traditional speech interaction. The paper focuses on the essence of the professional communication language in the concept of modern scholars of the second half of the 20th and the first two decades of the 21st century within the study of the linguistic personality of a particular social group as a subject of professional activity. The content of the notions of “a linguistic personality” and “a professional linguistic personality” is determined. The main focus is on identifying units of military jargon and military slang in the speech of American military bloggers as a way of expressing the attitude of military personnel to military service. The scientific novelty lies in the approach to the study of the professional linguistic personality of the US Armed Forces representatives from the perspective of its ethnic identity. In addition, an original feature of American servicemen is found – the presence of explication linguistic means of lexical features of speech. As a result, positive and negative images of a professional linguistic personality were recreated based on the texts of American military bloggers, in particular, emotionally charged elements of vocabulary (military jargon and military slang).
The monograph “A. P. Chekhov and Crimea” by A. G. Golovacheva. 2nd edition, revised and expanded. Moscow: Bakhrushin Theatre Museum, 2022. 200 p.: illustrated: Book review
Authors: Skibina Olga Mikhailovna
Published: January 2024

The book under review is based on extensive factual and archival material and offers the history of the last years of A. P. Chekhov’s life and creative work in Crimea. The book introduces the writer’s contradictory impressions of Crimea, the literary tradition in the depiction of the southern coast of Crimea by Russian writers and the reflection of Crimean places in the works by Chekhov himself.
Tradisi Piduduk dalam Perkawinan Masyarakat Banjar di Kabupaten Balangan, Kalimantan Selatan: Perspektif Maqasid Syariah
Authors: Rahmatillah Nor Annisa , Subeitan Syahrul Mubarak , Abubakar Fatum
Published: January 2024

This study aims to describe the piduduk tradition in marriages in the Banjar community, Balangan District, South Kalimantan. This qualitative research collects data in the field through observation and interviews, then analyses using the Islamic maqashid approach. This research shows that the piduduk of the Banjar people is still strong in every wedding ceremony. The Banjar people believe that if this tradition is abandoned when holding a wedding ceremony, then the wedding ceremony will not run smoothly. This tradition is carried out by older people when one of their relatives has a wedding. As for the implementation of the piduduk carried out by the Banjar community, it can cover five objectives of maqasid sharia, namely: First, to protect religion (hifdz-ad-din) as obedience to parents; Second, maintaining reason/mind (hifdz al-aql) as a valuable tradition for society; Third, taking care of the soul (hifdz an-nafs) as giving food to the bride and groom in the form of brown sugar and coconut so that the bride and groom stay healthy and have stamina when they are side by side at the aisle; Fourth, guarding assets (hifdz al-mal) as gifts to event facilitators that are worth alms; and Fifth, protecting the offspring (hifdz an-nasb) as part of preserving the Piduduk tradition of the Banjar people.Keywords: Piduduk; Marriage; Maqasid Sharia. ABSTRAKPenelitian ini bertujuan untuk mendeskripsikan tradisi piduduk dalam perkawinan masyarakat Banjar di Kabupaten Balangan, Kalimantan Selatan. Penelitian ini merupakan penelitian kualitatif dengan mengumpulkan data di lapangan melalui observasi dan wawancara, kemudian dianalisis menggunakan pendekatan maqashid Syariah. Penelitian ini menunjukan bahwa tradisi piduduk masyarakat Banjar masih kental pada setiap upacara perkawinan. Masyarakat Banjar percaya apabila tradisi ini ditinggalkan ketika melangsungkan acara perkawinan, maka acara perkawinan tersebut tidak akan berjalan dengan lancar. Tradisi ini dilakukan oleh orang yang lebih tua ketika salah satu kerabatnya akan melangsungkan acara perkawinan. Adapun pelaksanaan tradisi piduduk yang dilakukan oleh masyarakat Banjar dapat melingkupi lima tujuan dari maqasid syariah, yaitu: Pertama, untuk menjaga agama (hifdz-ad-din) sebagai kepatuhan kepada orang tua; Kedua, menjaga akal/fikiran (hifdz al-aql) sebagai tradisi yang bernilai bagi masyarakat; Ketiga, menjaga jiwa (hifdz an-nafs) sebagai pemberian makanan kepada pengantin berupa gula merah dan kelapa agar pengantin tetap sehat dan berstamina ketika sedang bersanding di pelaminan; Keempat, menjaga harta (hifdz al-mal) sebagai pemberian kepada para fasilitator acara yang bernilai sedekah; dan Kelima, menjaga keturunan (hifdz an-nasb) sebagai bagian dalam melestarikan tradisi piduduk masyarakat Banjar.
TRANSFORMATIONAL LEADERSHIP OF PESANTREN TAHFIZD DARUL QURAN SURAKARTA LEADERS IN STRENGTHENING THE RELIGIOUS CHARACTER OF SANTRIWATI
Authors: Alqudsi Zainab , Anif Sofyan , Fathoni Achmad , Muhibbin Ahmad , Haryanto Sigit
Published: January 2024

Abstract: Education at Islamic boarding schools not only functions as a transfer of religious knowledge, but also as a place for the formation of religious character. The transformational leadership of Islamic boarding school leaders plays a central role in the process of producing a generation that combines academic skills with strong moral and spiritual character. Transformational leadership does not only involve managerial aspects, but also focuses on building female students' character, morality and spirituality. This research aims to explore and understand the positive impact of transformational leadership of Islamic boarding school leaders in forming a religious generation at the Tahfizh Daarul Qur'an Islamic Boarding School, Surakarta. This research method uses descriptive qualitative. This research found that the transformational leadership of Islamic boarding school leaders in the idealized influence dimension in strengthening the religious character of female students was carried out with the strategy of nurturing with the heart and educating by example, holding muhadharah activities with the aim of forming the character of female students, memorizing the Qur'an which would then be carried out by reciting the Qur'an. an, providing formal education based on science and technology.Key Words : Transformational Leadership, Islamic Boarding School Leader, ReligiousAbstrak: Pendidikan di pesantren tidak hanya berfungsi sebagai transfer ilmu agama, tetapi juga sebagai tempat pembentukan karakter religius. Kepemimpinan transformasional pimpinan pesantren memainkan peran sentral dalam proses mencetak generasi yang memadukan kecakapan akademis dengan karakter moral dan spiritual yang kuat. Kepemimpinan transformasional tidak hanya melibatkan aspek manajerial, tetapi juga berfokus pada pembentukan karakter, moralitas, dan spiritualitas santriwati. Penelitian ini bertujuan untuk mengeksplorasi dan memahami dampak positif kepemimpinan transformasional pimpinan pesantren dalam membentuk generasi religius di Pesantren Tahfizh Daarul Qur’an Surakarta. Metode penelitian ini menggunakan kualitatif deskriptif. Penelitian ini mendapatkan hasil bahwa kepemimpinan transformasional pimpinan pesantren dalam dimensi idealized influence dalam menguatkan karakter religius santriwati dilakukan dengan strategi mengasuh dengan hati dan mendidik dengan keteladanan, mengadakan kegiatan muhadharah dengan tujuan untuk membentuk karakter santriwati, hafal Qur’an yang selanjutnya akan dilakukan khatmil Qur’an, pemberian pendidikan formal berbasis sains dan teknologi.Kata Kunci : Kepemimpinan Transformasional, Pimpinan Pesantren, Religius
Translation Strategies in Subtitling Figurative Language on Batwoman Series
Authors: Bastian Dara Azalia , Sujana Sujana
Published: January 2024

This research discussed about subtitling of figurative language in Batwoman drama series. The aims of this research to find kinds of figurative languages used in Batwoman and to identify subtitling techniques used in figurative languages in Batwoman. The researcher use Perrine’s theory to find figurative language and Gottlieb’s theory find subtitling strategies. The researcher focused on each character’s dialogue, those are Batwoman (Kate Kane), Alice, Luke Fox, The method that the researcher used is qualitative method. The result of this research is the researcher found 83 data in the series. For the figurative, the frequency of the data is 15 similes, 8 metaphors, 2 apostrophes, 24 metonymies, 8 synecdoches, 2 symbols, 18 overstatements, and 6 ironies. For the subtitling strategies, the researcher found 3 expansions, 2 paraphrases, 52 transfers, 24 imitations, 1 transcription, and 1 condensation.
Translation of Indonesian Interjection into English
Authors: Zulfah Annisa Siti , Noverino Romel
Published: January 2024

Language is a system of sound and character signs used to communicate within and between communities. Interjection is one of the language parts that are commonly used as a daily expression. Translation has a significant role in order to reach the receptor for understanding the source language. The study of this research focuses on the analysis of translation techniques for Interjections in the novel “Matahari” into English. The purpose of this study is to describe the translation techniques applied in translating interjections and to know what translation technique is mostly employed in translating interjections from Indonesian-English in the novel “Matahari”. The researcher conducts a qualitative descriptive method. This study is also conducted by using analyzing the translation technique, comparing and classifying the data, getting the data percentage, and drawing the conclusion. The researcher collectes the data from the novel and there were 45 data. The result of the data analysis shows that there are 13 data (28,9 %) using borrowing, 12 data (26,7%) using literal translation, 5 data (11,1%) using adaptation, 5 data (11,1%) using linguistic amplification, 5 data (11,1%) using established equivalent, 3 data (6,7%) using substitution, and 2 data (4,4%) using amplification. The researcher found the most common technique used is Borrowing.
Flouting Maxim in Spider-Man: No Way Home Movie
Authors: Sari Putri Mayang , Jamaris Anita
Published: January 2024

The aims of this research are to find out the types of Flouting Maxim and Flouting Maxim that most frequently occurred in the Spider-Man: No Way Home movie. This research used Cooperative Principles theory that proposed by Grice (1975). The researcher used descriptive qualitative method and documentation techniques in collecting data. The data of this research were taken from the utterances by all the characters in the Spider-Man: No Way Home movie. Based on the result, the researcher found 32 data contained Flouting Maxim based on Grice’s theory. The researcher found 4 types of Flouting Maxim, there are; 7 data of Flouting Maxim of Quantity, 8 data of Flouting Maxim of Quality, 10 data of Flouting Maxim of Relation, and 7 data of Flouting Maxim of Manner. Based on the result, it can be concluded that Flouting Maxim of Relation is the Flouting Maxim that most frequently occurred in the Spider-Man: No Way Home movie.
An Analysis of Figurative Language in Autumn!’S Album “Golden Child, Chapter 3”
Authors: Kamarizki Reynaldi , Wuryandari Dyah Ambar
Published: January 2024

Figurative language refers to the use of expressive linguistic tools that transcend literal interpretation to convey deeper meanings and evoke vivid imagery. In light of this definition, this research’s objective is to find out the types of figurative language and to find out the most dominant type of figurative language in Autumn!'s album "Golden Child, Chapter 3" by utilizing Perrine's theory of figurative language. The researcher has employed the qualitative research method in this research.  The researcher found 8 types of figurative language from 78 datum in this figurative research. It includes the following; Simile (18 datum), Metaphor (21 datum), Personification (3 datum), Synecdoche (5 datum), Metonymy (10 datum), Paradox (1 datum), Hyperbole (16 datum), and irony (4 datum). This research showed that the most dominant type of figurative language is Metaphor with 21 data.