bluuebunny/crossref_metadata_2025 huggingface dataset:
Evidence of an emerging triple-reassortant H3N3 avian influenza virus in China
Authors: He Lei , Zhang Yuhao , Si Kaixin , Yu Chuan , Shang Ke , Yu Zuhua , Wei Ying , Sarker Subir , Chen Songbiao
Published: September 2024

The H3 subtype of avian influenza virus (AIV) stands out as one of the most prevalent subtypes, posing a significant threat to public health, and a novel triple-reassortant H3N3 AIV, designated A/chicken/China/16/2023 (H3N3), was isolated from a chicken in northern China. The complete genome of the isolate was determined using next-generation sequencing, and the AIV-like particles were confirmed via transmission electron microscopy. Phylogenetic analyses revealed that eight genes of the H3N3 isolate clustered within the Eurasian lineage of AIVs, indicating the novel H3N3 isolate has various constellations and was generated by complex reassortment events involving H3N8, H9N2, and H10N3 subtype influenza viruses. Strikingly, the HA gene of the H3N3 isolate exhibited the closest evolutionary relationships to a human-derived H3N8 influenza virus, posing a potential threat to public health. Additionally, the presence of Q226 and T228 in the HA protein suggests the H3N3 virus preferentially binds to α-2,3-linked sialic acid receptors. While the HA cleavage site motif (PEKQTR/GIF) and the absence of E627K and D701N mutations in PB2 protein classify the virus as a characteristic low pathogenicity AIV. However, several mutations in internal genes raise concerns about potential increases in viral resistance, virulence, and transmission in mammalian hosts. Overall, this study provides valuable insights into the molecular and genetic characterization of the emerging triple-reassortant H3N3 AIVs, and continued surveillance of domestic poultry is essential for monitoring the H3N3 subtype evolution and potential spread.
Bioefficacy of Sycanus reclinatus Stal Dohrn, (Hemiptera: Reduviidae) on the Euproctis fraterna Moore (Lepidoptera:Lymantriidae)
Authors: Muthupandi M , J Merline Shyla. , A Manimaran
Published: September 2024

Sycanus reclinatus Dohrn, (Hemiptera: Reduviidae) is a reduviid predator of many agricultural crop pests. A laboratory experiment was conducted to evaluate the bio efficacy of this predator using functional response as a tool. Sycanus reclinatus Dohrn third, fourth, and fifth instar nymphs and adults on Euproctis fraterna Moore were evaluated. The predatory rate gradually increased from the third instar nymph to adults. S. reclinatus killed and consumed more prey in high densities (4.5, 4.6, 6.0 and 4.5 prey/ predator). The rate of discovery gradually increased when the predator grew older. Handling time also increased when the predator grew older. S. reclinatus showed an exponential (Type II) functional response when E. fraterna was exposed to it. Type II functional response is more pronounced in pests. Such different patterns show that the predator needs to adapt distinct strategies according to the kind of prey available in the field. The biological control potential of S. reclinatus concerning the pest E. fraterna shows that the, searching time, handling time, and number of prey killed depended upon the prey densities and predator life stages. Hence, the predator S. reclinatus can be utilized to control and manage the selected lepidopteran pest.
Research on Optimization Grading Method of Manufactured sand Concrete Based on Particle Shape Image Representation
Authors: Pang Shanshan , Yang Yahan , Tang Wenhui , Wang Bingshu , Yu Zeming
Published: September 2024

It is crucial to optimize the proportioning parameters of manufactured sand concrete by combining particle shape images. This article adopts a research method combining theoretical analysis and physical experiments, using DIP method to obtain quantitative image characterization parameters of mechanism sand particle shape,study the mechanical performance laws of manufactured sand concrete affected by different characterization parameters, and obtain reasonable quantitative parameters of particle shape characterization and optimized mix proportion of manufactured sand concrete. The research results indicate that: (1) The DIP particle shape image method is used to accurately obtain the random parameters of dispersed manufactured sand, and the roundness, edge angle, and particle size ratio are used to characterize the particle shape distribution characteristics more accurately. Small particle size manufactured sand exhibits more uniform particle shape images. (2) Establishing an optimization model for compressive performance with water cement ratio, fly ash mineral powder admixture, and sand ratio as influencing factors, analyzing the changes in mechanical properties of Manufactured Sand concrete under the influence of influencing factors.(3) Comparative analysis shows that the water cement ratio has the most significant impact on the compressive strength of manufactured sand concrete, while the effect of fly ash and mineral powder admixture and sand ratio is relatively small. The optimal ratio is a water cement ratio of 0.32, mineral powder content of 20%, and sand ratio of 45%. The research results provide effective data support for the quantitative application of manufactured sand production.
Performance of soil total nitrogen monitoring model using optimal preprocessing combinations of in-situ and indoor spectra
Authors: Dai Yuanshui , Kong Yacong , Li Gang , Lv Xin
Published: September 2024

To explore the performance of in-situ spectral monitoring of soil total nitrogen, this study focused on cotton fields with different soil textures and sampled soil from 0–60 cm depth. Three different preprocessing combinations were applied to the indoor and in-situ spectra, and four modeling methods including the Generalized Regression Neural Network (GRNN), Random Forest Regression (RFR), Support Vector Machine Regression (SVR), and Ordinary Least Squares Regression were optimized using the Northern Goshawk Optimization (NGO) algorithm. The goal was to establish and select the best model for monitoring soil total nitrogen content in each soil layer. The results showed that: (1) Compared with no preprocessing, different preprocessing combinations improved the model accuracy by 0.19–0.49. The optimal preprocessing combination for the surface soil was First Derivative (FD) - Standard Normal Variate (SNV) - Z-score - Savitzky-Golay (SG), and for the medium and deep soil was FD - SNV - Continuum Removal (CR) - SG. (2) The optimized NGO-GRNN model outperformed the GRNN model, with an improvement of 60%, 12%, and 19% in R2 for the shallow, medium, and deep soil layers, respectively. (3) The model constructed using indoor spectra performed better than the in-situ spectra in monitoring soil total nitrogen content. However, the in-situ spectra-based models for different soil layers had an R2 greater than 0.6, indicating good monitoring performance and eliminating the laborious steps of indoor spectral processing. This study provides theoretical and technical support for rapid acquisition of nutrient information in various soil layers of cotton fields using in-situ spectral monitoring, demonstrating feasibility and robustness.
Unlocking disease associations during prefrontal cortex development with scRNAseq
Authors: Farley Kathryn Olivia , Chen Kevin G. , Lassmann Timo
Published: September 2024

Background
The brain consists of tissue comprising billions of neurons intricately connected through trillions of synapses. Throughout human development, from conception to adulthood, cells in the brain undergo significant changes, assembling functional circuitry over time orchestrated by finely tuned programs of gene expression. Understanding the spatiotemporal signalling that governs brain development and the impact of gene mutations on developmental programs remains a significant challenge. Here we identify the role of genetic variants in brain development to advance the development of therapeutic options.
Results
This computational study leverages developmental prefrontal cortex single-cell transcriptomic data to associate specific cell types with disease states. Using un-supervised techniques, we identify temporal gene expression patterns and gene co-expression networks enriched for genes associated with neurological disorders. By systematically applying these approaches we identify key cell types and developmental stages associated with disease emergence and progression
Conclusions
Our approach identifies important cell types and developmental stages relevant to diseases directly from single cell data. By pinpointing cells, genes, and their neighbourhoods, our approach has the potential to contribute to the discovery of new targets and treatment avenues. We hope our work will advance the management of brain-related disorders.
Assessing multi-hazard risk in Gulmidarbar Rural Municipality, Gulmi, Nepal
Authors: Tandan Sundar , Adhikari Basanta Raj , Karna Akhilesh Kumar
Published: September 2024

The occurrences of different kinds of natural hazards in the Nepal Himalaya is increasing in recent years. The complex interaction between these hazards is poorly understood. The multi-hazard mapping underscores the pivotal role of hazard maps in disaster risk reduction, advocating for creating a multi-hazard map despite associated challenges in the Gulmidarbar Rural Municipality. The Individual hazard maps for landslides, forest fires, floods, and earthquakes were generated. Rigorous validation processes, including field verification, were done to ensure the accuracy of individual hazard maps before integration into the comprehensive multi-hazard map using the Analytical Hierarchal Process (AHP). The vulnerability was calculated at the lowest administrative levels incorporating physical and socio-economic factors. The multi-hazard map is prepared by combining the ward-level hazard and vulnerability. The analysis shows that Ward No.4 has high risk followed by Ward No.1. This analysis is important to the mayor and other policymakers in decision-making, emergency response, and urban planning, aiming to develop robust strategies that minimize losses and enhance resilience in the studied region
From Feasibility to Insight: Piloting Feature Extraction from FHIR Cohorts to Advance Clinical Research
Authors: Rosenau Lorenz , Gruendner Julian , Behrend Paul , Triefenbach Lucas , Kurscheidt Maximilian , Majeed Raphael W. , Prokosch Hans-Ulrich , Ingenerf Josef
Published: September 2024

Background Interoperability between healthcare institutions and the standardized sharing of health data pose ongoing challenges. The Medical Informatics Initiative (MII) and the German Portal for Medical Research Data (FDPG) leverage the Fast Healthcare Interoperability Resources (FHIR) standard to address these issues. However, their capability for standardized and automated data extraction still needs to be added.Objective This research explores enhancing the FDPG's functionalities beyond its current scope of distributed feasibility studies (e.g., for cohort size estimations) within the existing MII framework. The focus is on extracting a subset of data represented in FHIR for specific cohorts aiming to uncover actionable insights from the health data repositories, thus extending the portal's utility beyond feasibility analyses.Methods We developed a prototype focusing on designing a user interface and implementing a local data extraction process. Based on a detailed comparison of existing data extraction tooling, we decided on the Pathling Server, chosen for the alignment of its capabilities with the problem space of data extraction and feasibility and potential as an all-in-one server solution for the FDPG architecture.Results We implemented a prototype that showcases the possibility of expanding the FDPG's feature set for local data extraction at clinical sites. Further, we were able to showcase its feasibility in providing researchers with means to extract CSV-formatted reports on specified cohorts based on a synthetic data set.Conclusion While a range of considerations are still required for extending the FDPG to support data extraction in a federated network, our work provides valuable insight. Namely, the value of providing an abstraction layer for researchers with an implicit translation to FHIR Path expressions and the benefit of a local CSV extraction. The approach of using Pathling requires staging project-specific data due to performance constraints. This poses privacy risks and should, therefore, be revisited. By presenting an early prototype, we hope to gather additional feedback from different stakeholders in the MII, including but not limited to clinical researchers, data stewards, and data privacy specialists.
The Genetic Landscape of Canine Tumors: Insights from the Canine Cancer Genome Atlas (CCGA)
Authors: Aresu Luca , Mazzone Eugenio , Marconato Laura , Fanelli Antonella , Cascione Luciano , Bertoni Francesco
Published: September 2024

The Canine Cancer Genome Atlas (https://caninecancergenomeatlas.org/) represents a groundbreaking advance in comparative oncology, offering an unprecedented wealth of genetic data across ten canine cancer types. This invaluable resource, encompassing 770 cases, reveals over 34,000 genetic variants, providing a comprehensive map of canine cancer genetics. By bridging the gap between canine and human oncology, the Canine Cancer Genome Atlas (CCGA) reveals shared oncogenic pathways and potential therapeutic targets. Key findings parallel human cancer genetics, with mutations in TP53, PIK3CA, and PTEN emerging as prominent features. The atlas also elucidates copy number alterations and mutational signatures associated with DNA repair deficiencies and carcinogen exposure. Through its user-friendly web platform, the CCGA equips researchers with state-of-the-art visualization and analysis tools, fostering collaboration and accelerating scientific discoveries. As the CCGA expands to incorporate multi-omics data, it promises to deepen understanding of cancer's molecular complexities. This indispensable resource not only advances veterinary oncology but also holds the potential to transform human cancer treatment, exemplifying the profound impact of comparative genomics in the battle against cancer.
compGWAS: a new GWAS tool allows revelation of the genetic architecture and risk stratification for the versatile pathogen Streptococcus pyogenes
Authors: Wang Peng-Ying , Liang Zhong , Chen Zhi-Song , Bao Yun-Juan , Castellino Francis J.
Published: September 2024

Background
Gene inactivations caused by loss-of-function mutations and regulatory changes caused by insertions/deletions (InDels) are common genetic factors closely related to phenotypic diversity or pathogenic versatility of many bacterial species. However, these genetic factors were usually ignored by the computational approach of genome-wide association studies (GWAS). It prevents the full understanding of the contributions of genetic variants to phenotypic diversity or the roles in shaping genetic architecture of bacterial species of diverse phenotypes. Group A Streptococcus pyogenes (GAS) is one of the most versatile pathogens causing a variety of primary diseases, as well as disease progressions, complications, and sequelae and is a promising species to do investigations in this regard.
Methods
By using GAS as a paradigm, we developed a new GWAS tool, compGWAS, to comprehensively identify phenotype-associated genetic variants that include not only SNPs, but also InDels and gene inactivations. The genetic architecture of GAS phenotypes was revealed by considering all these types of variants. A GWAS polygenic score (GPS) model was developed through integration of all types of associated variants for phenotype stratification.
Results
By leveraging this newly developed tool, we constructed a relationship network between 1,361 variants linked with 783 genes and eight GAS phenotypes. The network shows a high level of polygenicity of the GAS phenotypes (ranging from 6 to 148 genes) and pleiotropicity of the causal genes (as many as eight phenotypes). Further investigation revealed a unique genetic architecture of GAS phenotypes as a combination of many low-effect common variants and a small proportion of high-effect low-frequency variants with gene inactivations being predominant. By adding gene inactivations and InDels, the proportion of explained phenotypic variance increased by 7%-16%, resulting in a total explained variance as high as 50%. The high explained variance allowed us to construct a GPS model with high discriminatory capabilities in GAS phenotype stratification with the AUC > 80% in the validation dataset.
Conclusions
Our work provides a novel tool and analysis framework for investigating phenotypic effects and genetic characteristics of InDels and gene inactivations previously ignored. Our study has implications for understanding genetic architecture of versatile pathogens like GAS.
Maglev-like droplet-based transporters co-regulated by wettability and magnetic field
Authors: Zheng Huanxi , Zhang Yonghui , Zhang Jiahao , Li Yuheng , Mao Shanyi , Wang Yanan , Wang Ziheng , Yuan Zizhen , Liu Xin
Published: September 2024

The adhesion behavior of liquid droplets on solid surfaces is critical for natural transportation and industrial production. In particular, microrobots based on adhesion at solid-liquid interfaces have important applications in chemical reactions, cargo transport, and energy harvesting. However, current droplet-based manipulation strategies primarily depend on the structures or reactions between solid-liquid interfaces to achieve programmable droplets movement, while robust carrying capacity and precise synergistic operation of multiple droplets remain challenging. Herein, we propose a maglev-like droplet-based transporter system (MDTs) with adjustable structures to achieve precise droplets manipulation for robust cargo transportation and energy conversion. By controlling the magnetic fields and the droplet adhesion at the solid-liquid interfaces, the MDTs can precisely transport, climb and rotate, as well as efficiently convert mechanical energy into electricity for motion monitoring and self-powered devices. These findings deepen the understanding of force transport co-directed by surface wettability and magnetic fields, and broaden the utilization of these systems for cargo transportation and energy conversion, offering a great potential for contactless blind operation, lossless transfer and reactions, and powerless micro-electromechanical systems (MEMS).
Prognostication of Half Cell Potential for Slabs Cathodically Protected with AZ91D using eXplainable and Interpretable Machine Learning
Authors: Pandey Shikha , Murthy Yogesh Iyer , Gandhi Sumit
Published: September 2024

Purpose: This research investigates the use of twenty commonly applied regression methods to predict concrete corrosion. These models are assessed for accuracy and interpretability using SHAP and LIME analysis to provide structural health monitoring prognostic tools.
Design/Methodology/Approach: The research evaluated model performance using standard measures including RMSE, MSE, R², and MAE. Interpretability was evaluated using SHapley Additive Explanations (SHAP) and Local Interpretable Model-agnostic Explanations (LIME). The X and Y distances, concrete age, relative humidity, and temperature were input parameters while Half Cell Potential (HCP) values were considered output. The experimental dataset consisted of observations taken for 270 days.
Findings: Gaussian Process Regression (GPR) models with Rational Quadratic, Square Exponential, and Matern 5/2 kernels outperformed others, with RMSE values around 16.35, MSE of roughly 267.50, and R² values near 0.964. Bagged and Boosted Ensemble models performed well, with RMSE around 17.20 and R² values over 0.95. Linear approaches, such as Efficient Linear Least Squares and Linear SVM, resulted in much higher RMSE values (~40.17 and ~40.02) and lower R² values (~0.79), indicating decreased prediction accuracy.
Practical Implications: The findings highlight the effectiveness of GPR models in forecasting corrosion in concrete buildings. The use of both SHAP and LIME for model interpretability improves the transparency of predictive maintenance models, making them more reliable for practical applications.
Originality/Value: This study reduces the gap between model accuracy and interpretability in predicting concrete corrosion by proposing a data-driven method to structural health monitoring. The combination of GPR models and ensemble approaches provides a solid foundation for future research and practical applications in predictive maintenance. This comprehensive approach underscores the potential of data-driven methods for predictive maintenance in concrete structures, with implications for broader applications in various industries.
The Spectro-Polarimeter (SP) of the Andrei B. Severny Solar Tower Telescope (STT) at the Crimean Astrophysical Observatory: Optical Design and Implementation
Authors: Kutsenko Alexander , Terebizh Valery , Dolgopolov Andrei , Abramenko Valentina , Plotnikov Andrei , Semyonov Dmitriy , Skiruta Vladimir , Lopukhin Vyacheslav
Published: September 2024

The Spectro-Polarimeter (SP) is a new instrument installed at the upgraded Andrei B. Severny Solar Tower Telescope (STT) at the Crimean Astrophysical Observatory. The instrument is a traditional echelle slit dual-beam spectropolarimeter with temporal modulation of the polarization. STT-SP provides simultaneous spectropolarimetric observations of the Sun within three 15 Angstrom wide spectral ranges around photospheric Fe I 5250, Fe I 5324, and chromospheric Mg I b2 5172 spectral lines. The spectral resolution of the instrument reaches 70,000 with the seeing-constrained slit width of 1 arcsec. The field-of-view of STT-SP is 200 arcsec allowing one to map a moderate size active region within a single raster scan. The instrument will provide new opportunities in the analysis of magnetic fields and thermodynamics of the lower atmosphere of the Sun. In this paper we describe the optical design of STT-SP and present the preliminary results acquired during the commissioning of the instrument.
A retrospective study on the admission and management of acute cases of abdominal aneurysms in Damascus Hospital
Authors: Assaf Mhmad Abo , Ali Diaa Haj , Kubtan Assem
Published: September 2024

The importance of research
The importance of the research lies in that it sheds light on an important medical issue, which is abdominal aneurysm cases and their management in Damascus Hospital, to measure the spread of this disease among our patients and determine its consequences, severity, and prognosis to be able to control it.
Research Materials and Methods
A retrospective study was conducted on a group of patients attending Damascus Hospital - General Surgery Department who were diagnosed with abdominal aortic aneurysm randomly from January 2019 until January 2024.
A questionnaire was conducted and the individuals participating were followed up during the research period, data was reviewed under the supervision of the research supervisor.
Results
The sample was divided into 3 categories according to age. 72% of the patients were 61-80 years old,(an average of 71 years). Then we searched for the presence of medical histories that predispose to the occurrence of aneurysms, and we linked them to several variables within statistical relationships, where it was found that 86.8% of the patients were suffering from hypertension.
In the end, Research and statistics showed that 28% were presented with a story of abdominal pain, 20% of the patients were asymptomatic and were discovered by chance and were admitted to the General Surgery Department. Others were presented with a complaint unrelated to aneurysms.
Conclusion
It is essential to publish awareness campaigns on the need to educate medical staff about methods of investigating and diagnosing aneurysms and ways to deal with them, and to publish scientific research on the complications of aneurysms, highlighting their rupture, and linking them to the location of the aneurysm and the general condition of the patient.
Verfügbarkeitsfantasien des Lifelogging
Authors: Burgfeld-Meise Bianca , Dehmel Lukas
Published: September 2024

Die fortschreitende Digitalisierung hat weitreichende Konsequenzen für gesellschaftliche Kontexte wie etwa Produktions- und Wertschöpfungsketten, das Rechtssystem, ökologische Aspekte und vieles mehr. Zeitgleich sind Digitalisierungsphänomene schwer einzugrenzen und können sehr unterschiedliche Aspekte beinhalten. Dies ist besonders dann der Fall, wenn die Zusammenhänge zwischen Selbst und Digitalisierung im Zentrum des Interesses stehen. Sind wir unter den Bedingungen des Digitalen algorithmisiert oder digitalisiert oder ist dies zu technikdeterministisch gedacht? Was können solche Diagnosen überhaupt aussagen? Um sich diesen Fragen anzunähern, diskutieren wir im Beitrag mit dem Konzept des «medialen Selbst» nach Faßler eine Perspektive, in der zunächst ein theoretisches Verständnis für medienspezifische und pädagogische Zugänge zur Anthropologie erarbeitet wird. Auf dieser Basis beschäftigen wir uns exemplarisch mit dem Phänomen Lifelogging als zeitgenössischer digitaler Kulturpraktik und stellen die qualitative Methode der «seriell-ikonografischen Fotoanalyse» nach Pilarczyk und Mietzner vor, um uns dem Phänomen empirisch anzunähern. Im Anschluss wird die Methode anhand der Analyse von Bildmaterial eingesetzt. Bei dem Bildmaterial handelt es sich um Fotografien von Studierenden, die visuell die Bedeutung von digitalen Medien für ihren Alltag thematisieren. Mit der sukzessiven Auswertung und Abstraktion der Analyse werden am Beispiel Lifelogging sozusagen Kernelemente des medialen Selbsts unter den Bedingungen des Digitalen erarbeitet. Unter einer z. B. von Hummrich beschriebenen pädagogisch-kasuistisch angelegten Untersuchungsperspektive erarbeiten wir in dieser empirisch unterfütterten Form theoretisierende Einblicke auf derzeitige Mensch-Medien-Welt-Relationen im Lifelogging, die sowohl vom Individuum als auch durch digitale Medien geprägt sind und zur Diskussion anregen.
Bewegungen
Authors: Hartogh Johannes
Published: September 2024

Die Digitalisierung lässt sich nicht auf die Hervorbringung neuer Technologien reduzieren. Sie bedeutet eine grundsätzliche Veränderung von Lebenswelten. Erfahrungen zu machen, bedeutet heute auch, mit Digitalität umzugehen. Neue Technologien und Digitalität verändern Wahrnehmungsformen, Kommunikations- und Erfahrungsmöglichkeiten. Der vorliegende Beitrag untersucht Bewegung als Strukturmoment von Erfahrung im Kontext der Digitalität. Erfahrungsmöglichkeiten werden dabei im Spannungsfeld von Software, digitalen Netzwerken, Daten und Datenbanken sowie digitaler Materialität betrachtet. Dabei zeigt sich, dass Digitalität besonderes Potenzial für das Entwerfen verschiedener Perspektiven auf Wirklichkeit bietet. Bewegung lässt sich in diesem Zusammenhang als bildendes Moment von Erfahrung verstehen. An die neuen Erfahrungshorizonte, die sich im Kontext der Digitalität ergeben, schliesst die Frage nach pädagogischen Konsequenzen an.
Investigation into forces on offshore piles with constant and linearly varying diameters using CFD and extended Morison equation under separate wave and current loadings
Authors:   Istanbul Technical University, Faculty of Naval Architecture and Ocean Engineering, Bal Kemal , Bayraktar Bural Deniz
Published: September 2024

This study presents a comparative analysis of hydrodynamic forces on cylindrical offshore piles with both constant and linearly varying diameters utilizing computational fluid dynamics (CFD) simulations. The classical Morison equation is evaluated alongside an extended version to address limitations in predicting forces on geometrically complex structures. Mesh convergence studies are performed to select the optimum grid size for separate wave and current simulations. The focus is on test cases characterized by small Keulegan-Carpenter (KC) numbers and relatively high Reynolds (Re) numbers within both inertia-dominated and diffraction zones. Numerical simulation results are utilized to compare the force predictions of the classical Morison equation and the extended Morison equation. It is observed that the classical Morison equation performs adequately for constant diameter piles, but it fails to predict forces on variable diameter piles accurately. In contrast, the extended Morison equation, incorporating nonlinear effects and variable cross-sections, provides significantly more accurate force predictions, particularly in the diffraction zone compared to the numerical simulations. This study emphasizes the critical importance of accounting for geometric variations, such as linearly varying pile diameters, under separate waves and currents loadings in hydrodynamic force calculations. These considerations support the development of enhanced design methods and optimization strategies, leading to safer and more efficient offshore structures.
Natural conditions of Varandey coastal tundra. Anthropogenic transformation of natural landscapes
Authors: Martynov S. V.
Published: September 2024

The author aims to characterize natural conditions in the coastal area of the Barents Sea, from the settlement of Varandey to the Perevoznoye field. The research covered an area of 20  km2, 40  km long. An integrated climatic characteristic of the studied area is given, including the direction and speed of natural processes forming its shape, cryogenic processes, flora and fauna conditions, soil cover formation. The geomorphological, geological, and hydrological features of the area are outlined. The heterogeneity of the water–salt regime of the coastal area, typical of the northern seas of the Arctic, including the Barents Sea, is noted. In the laidas, the prevalence of accumulation of easily soluble salts over their removal is established, which allows the soils to be distinguished in terms of their salinity. Here, halophytic species are identified. The vegetation cover of the studied area is characterized according to the habitat of flora representatives. The research identified 100 species of vascular plants, 51 species of lichens, and 65 species of mosses. A soil survey found 27 soil varieties, which form the structure of the soil cover; their morphological and physicochemical characterization are given. The data obtained during field studies and remote sensing data were used to determine the structure of landscapes to the level of terrain types and units, as well as to propose their description. Their ecological and geochemical typification is carried out. The fauna composition was assessed based on state registration data and open sources; field observations with reference to biotopes were used. The dynamics of fauna population on the Barents Sea coast was assessed retrospectively. Field survey and remote sensing data made it possible to identify areas with anthropogenic disturbance of tundra landscapes. A typification of the identified anthropogenic disturbances of the natural environment and their areas within the survey area is proposed. The data obtained can be used as signs when assessing the state of natural environments in the coastal part of the northern seas of the Arctic, similar in terms of natural and climatic conditions.
Main directions in the development of non-lethal weapons applicable in the Arctic region
Authors: Krents S. I.
Published: September 2024

The author discusses the current and promising means and methods of non-lethal confrontation. Non-lethal war is a violence aimed at the social death of the enemy without their physical elimination. Social death is a key concept in non-lethal (information, cyberwar, etc.) warfare.
Two infinite families of facets of the holographic entropy cone
Authors: Czech Bartlomiej , Liu Yu , Yu Bo
Published: September 2024

We verify that the recently proven infinite families of holographic entropy inequalities are maximally tight, i.e. they are facets of the holographic entropy cone. The proof is technical but it offers some heuristic insight. On star graphs, both families of inequalities quantify how concentrated/spread information is with respect to a dihedral symmetry acting on subsystems. In addition, toric inequalities viewed in the K-basis show an interesting interplay between four-party and six-party perfect tensors.
Evaluation of Science Education for Students with Visual Impairment: Views of Teachers and Administrators
Authors: Sellioğ Aydın , Sürmeli Hikmet
Published: September 2024

Introduction: Science education for students with visual impairment requires an inclusive education system. Understanding the science learning process of these students and determining their problems and needs in education constitute the basis of inclusive education. Therefore, it is crucial to evaluate the teaching strategies and material choices of science teachers to create an effective and accessible learning environment. School administrators are also decisive in providing support and resources, developing teachers and meeting the needs of this process. Therefore, this study aimed to examine the opinions of science teachers and school administrators working in secondary schools for the visually impaired about the difficulties encountered by students with visual impairment in science education and solution suggestions.
Method: The present study was designed with case study, one of the qualitative research designs. The study group consisted of 24 participants, including 14 science teachers and 10 school administrators working in secondary schools for the visually impaired in Türkiye in the 2022-2023 academic year. The data were obtained through a semi-structured interview technique. Content analysis was used to analyse the data.
Findings: The findings showed that the content of the curriculum was prepared intensively, the course duration was insufficient and the acquisitions were too many, teaching materials for many senses should be prepared and there were printing errors in the textbooks. It was determined that students had difficulties arising from the reader in the measurement and evaluation process.
Discussion: The findings obtained in this study suggest that there are needs in providing science education for students with visual impairment. In the teaching of science course, the problems arising from the visual problems of students affected by visual impairment make it difficult for them to have the same opportunities as their peers with normal development. Thus, there is a need to determine the special needs of the students and make educational arrangements for their disability levels.
A ÓTICA DOS PARADIGMAS SOBRE OS CONCEITOS DE LIDERANÇA
Authors: Gargary Ademir , Hoffmann Cíntia Dietrich , Franco Simone Carla Delfino
Published: September 2024

Burrel e Morgan, em 1979, categorizaram quatro paradigmas: funcionalismo, estruturalismo, estruturalismo radical e humanismo radical. Sendo que os dois primeiros compõem a sociologia da regulação e os dois últimos, a sociologia da mudança radical. A liderança é fundamental para as organizações que desejam alcançar seus objetivos. O presente trabalho tem por objetivo identificar teorias de liderança em cada um desses paradigmas.
APRESENTAÇÃO
Authors: Acadêmico Editores Pensar
Published: September 2024

Revista da Faculdade de Ciências Gerenciais de Manhuaçu – FACIG (ISSN 1808-6136). Pensar Acadêmico, Manhuaçu, MG, v. 11, n. 2, Agosto-Dezembro, 2014.
ESTRATÉGIA DE SAÚDE DA FAMÍLIA E ATENÇÃO PRIMÁRIA A SAÚDE DE QUEM ESTÁ TRABALHANDO
Authors: Milagres Clarice Santana , Lodi Jucilene Casati , Cardoso Juliana Aparecida Fialho
Published: September 2024

Este trabalho enfoca as mudanças ocorridas na implementação das políticas de saúde do atual sistema apresentado no Brasil, o SUS, bem como a atenção que é dada àqueles trabalhadores que estão em seus processos de trabalho, quando o mesmo passa a maior parte do tempo útil diário em um expediente de trabalho contínuo. Objetivo: avaliar o atendimento prestado pela Unidade de Saúde da Família (USF) à população que trabalha em uma empresa da cidade de Vitória – ES. Materiais e Métodos: trata-se de uma pesquisa descritiva exploratória, com abordagem qualiquantitativa, realizada numa empresa de médio porte na cidade de Vitória. Para a análise descritiva, foram utilizadas as variáveis: utilização dos serviços de saúde, presença de Estratégia de Saúde da Família no bairro de moradia, conhecimento do seu funcionamento, dificuldade de acesso. Resultados: dos participantes da pesquisa, 79,6% não são atendidos pela estratégia, destes 53,2% não sabem da existência da unidade de saúde da família e 46,8% já ouviram falar, mas não sabem como funciona, porque o horário de atendimento da unidade coincide com o seu horário de trabalho, dificultando o acesso. Já 20,4% utilizam a unidade esporadicamente por possuírem plano de saúde. Quanto ao grau de satisfação, 49% estão satisfeitos com o atendimento recebido na unidade e 35% estão insatisfeitos. Conclusão: há necessidade de se frisar a importância de informações e educação em saúde à população e melhoria na oferta de serviços do mesmo. Uma grande preocupação nos achados da pesquisa foi a identificação de pessoas que ainda desconhecem a existência da unidade de saúde da família, procurando outro tipo de assistência que supra suas necessidades de saúde e que ofereça atendimento após o horário comercial.
VIVER E MORRER COM DIGNIDADE: BREVES REFLEXÕES SOBRE A EUTANÁSIA E SEU SANCIONAMENTO NO BRASIL
Authors: Lamas Lívia Paula de Almeida
Published: September 2024

A eutanásia é um tema muito discutido ao longo dos anos e que sempre provocou opiniões controversas. Este artigo tem por escopo apresentar algumas reflexões sobre o assunto, realizando uma análise frente à legislação brasileira. Trata-se de assunto de grande importância que ainda precisa de discussão aprofundada por toda a sociedade, para que direitos fundamentais não venham a ser desrespeitados.
A MATEMÁTICA COM OS FRACTAIS
Authors: Frinhani Paulo Eduardo , Oliveira Hellen Cristine P. de , Brito Íris Felix de , Borges Lidiane Hott de Fúcio
Published: September 2024

O presente artigo tem como finalidade socializar aos leitores as possibilidades de observar que os fractais constituem um campo de investigação gigantesco na matemática atual e que apresentam propriedades fascinantes capazes de serem compreendidas por meio de sua beleza, aspectos, características e semelhanças. A identificação de métodos de ensino da geometria por meio dos fractais e de suas estruturas geométricas é relevante uma vez que a geometria fractal é um ramo da matemática que não é vista nas salas de aula, com base nisso, destaca-se a importância desse conhecimento ser divulgado para alunos e professores.
JURISDIÇÃO DOS DIREITOS HUMANOS NA ORDEM INTERNACIONAL E SEUS REFLEXOS NO ÂMBITO INTERNO
Authors: Arakaki Fernanda Franklin Seixas , Mendes Andréia Almeida
Published: September 2024

Tem por escopo esse artigo analisar a jurisdição dos direitos humanos no plano internacional, bem como seus reflexos e impacto no âmbito do Direito interno, tendo como pressuposto as bases filosóficas do direito humanitário. Num primeiro momento, enfoca-se a fundamentação dos direitos humanos abordando a discussão entre o universalismo e o particularismo sob uma base filosófica. Já num segundo plano, serão lançadas considerações sobre a proteção dos direitos humanos e o processo de jurisdicionalização desses na ordem internacional. Num terceiro momento, serão enfocadas considerações sobre a positivação das normas de proteção dos direitos humanos no plano internacional. Por último, será apresentado o impacto da jurisdição humanista internacional no plano do direito interno sob uma perspectiva principalmente pós-positivista.
EMPREGADOS DOMÉSTICOS: TRATAMENTO DISCRIMINATÓRIO SOB A ÓTICA DA TEORIA DO RECONHECIMENTO
Authors: Franklin Giselle Leite , Andrade Daniela Rafael de
Published: September 2024

O presente trabalho pretende analisar as experiências do reconhecimento negado, sobretudo do emprego doméstico, visando a verificar em que medida elas podem ensejar lutas por reconhecimento e mudança nas trajetórias profissionais. Conforme instrui Axel Honneth (1994), a negação dos direitos a uma pessoa corresponde a uma ‘morte social’, uma vez que diminui a sua auto-estima no tocante à capacidade que ela tem de se relacionar com os outros de igual para igual. A correção dessa injustiça, de acordo com o mesmo autor, vem pelo reconhecimento do cidadão, por parte dos outros cidadãos, como membro pleno da comunidade e possuidor dos mesmos direitos e deveres que cabem a qualquer outro cidadão, esse reconhecimento mútuo é a maneira pela qual o sujeito constrói uma auto-imagem positiva. Além do mais, a experiência do desrespeito relaciona-se às vivências afetivas dos seres humanos, de modo que constitui um impulso de resistência social e de conflito, para uma luta pelo reconhecimento. Tal tema vem alcançando os trabalhadores domésticos lentamente, consubstanciado num grupo minoritário que sempre foi colocado em posição de inferioridade em relação aos demais cidadãos.
O CONTEÚDO DE LÍNGUA PORTUGUESA EM QUESTÃO: O EMBATE ENTRE DOIS DISCURSOS
Authors: Dos Santos Adelino Pereira
Published: September 2024

A partir do referencial teórico e metodológico da Análise de Discurso de linha francesa, o trabalho de pesquisa consistiu na constituição e análise de um corpus formado por respostas de professores de Língua Portuguesa do ensino básico a um formulário contendo três questões: “O que é conteúdo de ensino-aprendizagem da disciplina Língua Portuguesa? Que conteúdo ensinar em Língua Portuguesa e por que ensiná-lo? De que maneira o conteúdo de Língua Portuguesa poderá contribuir para a formação cidadã do educando?” A análise permitiu a confirmação da hipótese da existência de dois discursos em um intricado jogo de oposição, embate, ambiguidade e entrelaçamento: o Discurso Pedagógico Tradicional sobre o conteúdo de Língua Portuguesa (DPT) e o Discurso sobre o conteúdo de Língua Portuguesa advindo dos Estudos Linguísticos Funcionalistas (DELF). O que compreendemos por DPT não é apenas uma questão de dizeres sobre o ensino de gramática normativa no ensino básico, discussão antiga, embora ainda atual. O DPT corresponde também à tradição de crenças e valores escolares que se consubstanciam e se fundamentam ideologicamente em práticas pedagógicas tradicionais. Compreendemos por DELF todos os saberes e dizeres sobre o conteúdo e a prática pedagógica de Língua Portuguesa enunciados a partir dos campos epistemológicos dos Estudos Linguísticos que concebem o texto, nas modalidades oral ou escrita e nas multimodalidades, em seus aspectos discursivos, pragmáticos, semântico-conceituais e formais como o objeto precípuo de ensino e aprendizado na educação básica.  O DPT e o DELF estabelecem uma luta simbólica pela hegemonia na determinação do conteúdo de ensino-aprendizagem de Língua Portuguesa no ensino básico. O primeiro estabelece relações de resistência, de permanência. O segundo busca conquistar espaço e legitimidade.  Os resultados dessa luta simbólica foram analisados nas  seções deste artigo.
GRAVIDEZ NA ADOLESCÊNCIA: ESTUDO EPIDEMIOLÓGICO REALIZADO NA CIDADE DE MANHUAÇU - MG
Authors: Sucasas Humberto Tostes de Faria , Ribeiro Guilherme Vieira Borchio , Sales Emanuel Costa , Flora Heytor dos Santos , Da Silva Juliana Santiago
Published: September 2024

A gravidez na adolescência é considerada por muitos como um problema de saúde pública. No Brasil os índices de fecundidade, que é o número de crianças nascidas por mulher, vem diminuindo, mas mesmo com o aumento da divulgação dos métodos contraceptivos, o número de registros de adolescentes grávidas é algo que chama atenção. O presente artigo visa mostrar uma nova concepção sobre a temática. Para isso foi realizado um estudo epidemiológico na cidade de Manhuaçu com o objetivo de comparar os dados coletados, relacionados ao tema, nas esferas municipal e nacional, podendo servir de embasamento para futuras pesquisas que visem intervenções neste âmbito. Foram elaborados gráficos que ilustraram uma proximidade entre os dados do município e os do país. Todavia foi observado um número maior de adolescentes grávidas na cidade em estudo.  Algumas concepções não consideram apenas a baixa idade materna como um determinante de adversidades. Deste modo, o que as causariam seriam fatores socioeconômicos e culturais, os quais acometem com maior frequência as jovens, e por isso é feita uma errônea associação.
Health Benefits and Safety of Postbiotics Derived from Different Probiotic Species
Authors: Harat Siyavash Ghadiri , Pourjafar Hadi
Published: September 2024

Nowadays, the usage of probiotics in the food industry has become common. It has been proven
that probiotics have many health benefits, such as adjusting the intestinal microbiome, boosting the immune
system, and enhancing anti-inflammatory and anti-cancer activities. However, in recent years, some concerns
have arisen about the consumption of probiotics, especially in vulnerable populations such as elderly, infants,
and people with underlying diseases. As a result, finding a new alternative to probiotics that has the same function
as probiotics and is safer has been prioritized. In recent years, postbiotics have been introduced as a great
replacement for probiotics. However, the safety of these compounds is not exactly confirmed due to the limited
in vivo research. In this review, the definition, classification, activities, limitations, and some advantages of
postbiotics over probiotics are discussed. Finally, the limited published data about the safety of postbiotics is
summarized.
Antimicrobial Peptides with Spermicidal Activity as New Contraceptive Agents: Killing Two Birds with One Stone
Authors: Zare-Zardini Hadi
Published: September 2024

Antimicrobial peptides (AMPs) have emerged as promising candidates for dual-action
contraceptive agents, offering both spermicidal and antimicrobial properties. This perspective explores
the potential of AMPs in developing novel contraceptive technologies, focusing on their application
in condom coatings and vaginal formulations. AMPs exert their effects through membrane
disruption mechanisms, targeting both microbial pathogens and sperm cells. Their broad-spectrum
activity against various microorganisms, coupled with spermicidal effects, makes them ideal for
multipurpose prevention technologies. The incorporation of AMPs into condoms could enhance
barrier protection, while vaginal applications offer non-hormonal, on-demand contraceptive options.
However, challenges, such as potential vaginal irritation, microbiome disruption, and the need
for long-term safety studies, must be addressed. Future research should focus on optimizing AMP
selectivity, developing stable formulations, and conducting comprehensive efficacy and safety trials.
The dual-action nature of AMPs aligns with the growing demand for integrated approaches to
sexual and reproductive health, potentially revolutionizing contraception and STI prevention. By
addressing current challenges and leveraging the unique properties of AMPs, researchers can develop
a new generation of contraceptive products that offer improved efficacy, safety, and user acceptability.