bluuebunny/crossref_metadata_2025 huggingface dataset:
Disinformation as a Contemporary Key Security Challenge in the Context of the Russian-Ukrainian Conflict
Authors: Kollár Dávid
Published: November 2022

False information, as well as the actors who spread it, have the power to promote negative narratives about society and discredit the work of serious media, non-governmental organizations, etc. Concerns are growing around the world that international NGOs and civil society organizations are vulnerable to online attacks and disinformation campaigns. These attacks are aimed at instilling fear and confusion, stigmatizing civil society, disparaging targeted organizations and their leaders, or promoting inaccurate views. The deliberately misleading nature of false information can make it difficult to study and analyze this issue. After studying the available professional sources, we can state that most of the studies carried out so far focus on three aspects, namely (1) identification of forms of false information and false content, (2) causes and dynamics of their spread, especially on social networks, and (3) impact to public opinion. An objective of this article was to characterize and clarify all three aspects, while we have tried to apply them to a specific case in the second part of the paper, specifically Russian-Ukrainian war. The main cause, or the motive of the primary creators of disinformation is to cause chaos in society and undermine trust in the state, which is directly related to inciting hatred and distrust towards state institutions. Disinformation has become a hybrid tool as a form of attack on the interests of every democratic state and the security of its citizens. Foreign powers often try to spread their narratives through their own or friendly media, or fictitiously independent activists, while they often communicate differently internally within their own state. Based on our findings, coordination with three key players is crucial in the fight against disinformation: technology companies, civil society and fact-checkers and academic institutions. In addition, strategic communication is one of the key tools in the fight against disinformation and requires a broad approach. Disinformation campaigns are often not limited to spreading fake news, but often focus on building a damaging narrative. This implies a close relationship between the fight against disinformation and strategic communication, public diplomacy and digital communication.
Tabular form of description of statistical methods and programs in scientific publications
Authors: Khromov-Borisov N. N.
Published: November 2022

A convenient tabular format for the description of statistical methods and software in scientific publications is proposed. It is recommended to include the name of the software, its version or update date, the name of the procedures used and their intent, obligatory references, and URL
Deradikalisasi Pemikiran Agama di lingkungan PTKIN Melalui Penguatan Mata Kuliah Perbandingan Madzhab: Studi pada Mahasiswa di UIN Prof. K.H. Saifuddin Zuhri Purwokerto dan UIN Sunan Kalijaga Yogyakarta
Authors: Basith Abdul , Labib Mughni
Published: November 2022

Radicalism is a religious ideology it’s characterized is intolerant to diversity and differences that occur in religious and life state, so that it threatens the integrity and upholding of the Unitary State of  NKRI. One of the causes of radicalism that can be embedded in individuals in society is because of the wrong understanding of religious teachings received from sources that cannot be accounted for. One of the efforts that can be done in the framework of the deradicalization project, and counter radicalism (anticipation of radicalism) is to instill a religious ideology that is characterized by wasathiyyah, moderate, and tolerant to diversity and differences in teachings and cultures in society. It was through strengthening the comparative madhhab courses in the PTKIN environment, especially students of the comparative madhhab study program. Based on research conducted by researchers, it turns out that there is a strengthening of comparative madhhab courses, according to the students, it is able to influence them to have a moderate paradigm, although according to some lecturers they think it is still weak, and cannot be maximized, so it needs a lot of curriculum development, and also create a climate and culture of discussion about moderation among students on campuses
Autoevaluación cultural e interseccionalidad: herramientas decolonizadoras en la enseñanza y formación psicológica
Authors: Díaz-Lázaro Carlos M. , Verdinelli Susana
Published: November 2022

Se propone la autoevaluación cultural y la interseccionalidad como estrategias para facilitar la integración de la perspectiva decolonizadora en el campo de la psicología. La autoevaluación cultural aboga por la examinación sincera y profunda de la influencia de los mensajes culturales dominantes sobre el género, la edad, la etnia, la habilidad, la clase social y la religión, entre otras variables, en nuestras creencias, actitudes y acciones. La interseccionalidad considera el cruce o intersección de las distintas dimensiones de diversidad social, presentando así un análisis mucho más complejo y dinámico en comparación con la perspectiva tradicional unidimensional. La perspectiva decolonizadora acoge y unifica una diversidad de movimientos críticos que fomentan la deconstrucción de los discursos dominantes con el propósito de desarrollar una psicología anclada en los valores de justicia e inclusión social. Las estrategias de autoevaluación cultural e interseccionalidad reafirman estos valores, fundamentando el desarrollo de una perspectiva decolonizadora.
Abordaje Musicoterapéutico en un Hospital General
Authors: Reibel Sofía
Published: November 2022

El presente artículo se realiza a partir de la rotación realizada por el Hospital General de Agudos Bernardino Rivadavia en el marco de la Concurrencia perteneciente al Gobierno de la Ciudad de Buenos Aires. Se comentará acerca de los encuentros en co-terapia realizados con una paciente en el Servicio de Clínica Médica quien es derivada al espacio por manifestar una posición depresiva, mostrando dificultades para responder desde el lenguaje verbal y falta de interés en vincularse con otros.
PERKEMBANGAN EKSPOR KOPI INDONESIA DI MASA PANDEMI COVID-19
Authors: Kusuma Arden Ida Bagus Wibisana , Setyari Ni Putu Wiwin
Published: November 2022

This study aims to determine the effect of COVID-19, coffee prices, and exchange rates simultaneously and partially on Indonesian coffee exports. The research was conducted in Indonesia in the monthly time period from 2018-2020 so that the number of observations was 36 observations. The research data was obtained through the government's official website as well as articles related to research which were then analyzed using multiple linear regression analysis techniques. Based on the results of the study, it was found that simultaneously COVID-19, coffee prices, and the exchange rate had a significant effect on Indonesian coffee exports. Partially, the COVID-19pandemic variable has a negative effect, while the exchange rate variable has a positive effect on Indonesian coffee exports. The price variable has no significant effect on Indonesian coffee exports. This result has the implication that the pandemic causes a decrease in the value of coffee exports compared to when there was no pandemic. This is because the pandemic will affect the economy of Indonesian coffee importing countries so that it will reduce Indonesian coffee exports.
PERBANDINGAN REALISASI NILAI EKSPOR PROVINSI ACEH BERDASARKAN PENGELOMPOKKAN NEGARA TUJUAN SEBELUM DAN MASA PANDEMI COVID-19
Authors: Ulya Ina Yatul , Anwar Samsul , Zakia Ulva
Published: November 2022

This study aims to group the export destination countries of Aceh Province into 3 categories, namely low, medium and high using the Kmeans clustering method to compare the realization of export values before and during the COVID-19 pandemic. The data employed were secondary data on the export value of Aceh Province to 38 destination countries in 2019 and 2020 which is sourced from the Foreign Trade Statistics of Aceh Province. The results showed a decrease in the average realized export value of Aceh Province during the COVID-19 pandemic. The export value from Aceh Province decreased in 22 countries (57.9%) during the pandemic. The K-means clustering analysis shows that most export destination countries for the Province of Aceh in 2019 and 2020 have low export value realizations. When compared to 2019, the only country that experienced a change in the export value category was Thailand, namely from the low category (cluster 3) to the medium category (cluster 2) during the pandemic. The Aceh government needs to make proactive efforts to increase the realization of export value, for example through adding variety to export commodities, providing subsidies and awards to local exporters and increasing the promotion of the potential of Aceh's resources to the international community.
Studi Faktor Psikologi Sosial dan Eksternal dalam Memengaruhi Kepatuhan Wajib Pajak
Authors: Kusuma Dewi Sayyidah Nurul , Wahyandono Matheas Prihargo , Seran Valeria Flora , Hatta Hambali Atika Jauharia
Published: November 2022

Tax compliance plays a very important role in increasing state tax revenues. This study aims to determine the effect of national pride, trust in authority, and the Automatic Exchange of Information (AEoI) system on tax compliance. The study also raises one social psychological factor, namely patriotism as a moderating variable that strengthens the relationship between national pride and tax compliance. The research uses a survey method and the sample is taxpayers who have NPWP. The results of the study indicate that there is an influence of national pride and the AEOI system on taxpayer compliance. There is no significant effect of the variable trust in authority on taxpayer compliance. The moderating variable in the form of patriotism cannot strengthen the influence of national pride on taxpayer compliance. The study concludes that the taxpayers of this study have a high spirit of nationalism and knowledge of the AEOI system, but trust in the authorities is still low.

Keywords: Tax Compliance; Nationalis Pride; Trust; AEoI System; Patriotism.
Analisis Financial Distress Untuk Memprediksi Potensi Kebangkrutan PT. X Yang Terdaftar Di BEI
Authors: Saladin Hendry , Oktariansyah Oktariansyah , Sari Novita
Published: November 2022

Financial distress can occur in every company. If financial distress is not immediately addressed, it can lead to bankruptcy. This study aims to determine the potential for bankruptcy at PT. X is listed on the Indonesia Stock Exchange (IDX) using the Springate model, the Zmijewski model and the Grover model. The method used is a qualitative method. The research sample is a statement of financial position and profit and loss of PT. X the first quarter of 2021 - the first quarter of 2022. The results of the research from the three models used are only the Springate model which predicts the company in a potentially bankrupt condition, while the Zmijewski model and the Grover model predict the company in a non-bankrupt potential condition.

Keywords: Financial Distress; Springate Model; Zmijewski Model; Grover Model
Analisis Faktor-Faktor yang Memengaruhi Ekspor Cengkih Indonesia ke Negara Tujuan Ekspor Cengkih Utama
Authors: Hasibuan Almanico Islamy , Novianti Tanti
Published: November 2022

One of the plantation commodities that has the potential to become a source of foreign exchange for Indonesia is cloves (Syzigium aromaticum L. Marr. and Perr.). National cloves production fluctuates, so that in cloves production it is known as the big harvest, medium harvest and small harvest. The clove cigarette industry is the main consumer of cloves because it absorbs 95% of the national clove production which is used as the main raw material in producing. This causes the volume of cloves to exported reduced, therefore research related to the analysis of the factors that affect the volume of clove exports to the main export destination countries needs to be carried out in order to produce recommendations to the government regarding the development of Indonesian clove exports, especially in the main clove export destination countries. The main destination countries selected in this study are India, Vietnam, Saudi Arabia, Singapore, Pakistan, and the United States which consistently import cloves from Indonesia in large volumes. This study uses a panel data analysis method using time series data for the period 2002-2019 and a cross section in six main destination countries for Indonesia's clove exports.
A National Survey of Prehospital Care Services of United Kingdom for Use, Governance and Perception of Prehospital Point of Care Ultrasound
Authors: Naeem Salman , Edmunds Christopher , Hirst Thomas , Williams Julia , Alzarrad Amir , Ronaldson James , Barratt Jon , Research, Audit, Innovation and Development Group East Anglian Air Ambulance , Research Network Pre-hospital Trainee Operated
Published: November 2022

Introduction: Point of care ultrasound (POCUS) has become a common practice in prehospital care over the last 10 years. There is lack of literature on its use and governance structure in United Kingdom (UK) prehospital care services. We aimed to survey the use, governance of prehospital POCUS among UK prehospital services and perceptions of clinicians and services regarding its utility and barriers to its implementation.  Methods: Four electronic questionnaire surveys were delivered to UK helicopter emergency medical service (HEMS) & clinicians, ambulance and community emergency medicine (CEM) services between 1st of April and 31st of July 2021 investigating current use, governance structure for POCUS and perception about its benefits and barriers. Invitations were sent via email to medical directors or research leads of services and using social media. Survey links remained live for two months each.  Results: Overall, 90%, 62% and 60% of UK HEMS, ambulance and CEM services respectively, responded to surveys. Most of the services used prehospital POCUS, however only two HEMS organisations fulfilled the Royal College of Radiology  governance criteria for POCUS. The most commonly performed POCUS modality was echo in cardiac arrest. Majority of clinicians judged POCUS to be beneficial and the common perceived benefit was promotion of enhanced and effective clinical care. Major barriers to its implementation included a lack of formal governance, limited literature supporting its use and difficulties in performing POCUS in prehospital environment.  Conclusion:  This survey demonstrates that prehospital POCUS is being provided by a majority of the prehospital care services and clinicians have found it beneficial in providing enhanced clinical care to their patients. However, the barriers to its implementation are relative lack of governance structure and supportive literature.
A Non-Resolving “Hematoma” Diagnosed as an Arteriovenous Malformation by POCUS
Authors: Freilich Michael , Galen Benjamin , Schwartz Deborah
Published: November 2022

Point-of-care ultrasound (POCUS) is a useful tool for the evaluation of soft tissue masses. We present the case of a patient with a mass on his forehead initially thought to be a slowly resolving hematoma. POCUS examination of the mass revealed a vascular structure more consistent with a post-traumatic arteriovenous malformation (AVM). This case illustrates how POCUS can be utilized to rapidly assess soft tissue masses and even identify unexpected vascularity.
Students’ Grammatical Error in Writing Narrative Text
Authors: Sinaga Yusni , Ramadhani Putri
Published: November 2022

Students made errors in writing narrative text. Two reasons why students made errors because less in grammar mastery and confuses to differenciate of the verb. This writing is to find out the grammatical errors. The method of research is descriptive quantitative. Process of data are analyzed by reading students’ writing firstly, identification, classification, tabulating, describing, and taking conclusion about the errors. After analyzing the data, it found that students made errors in omission, addition, misformation, and misordering categories. The highest frequency of item error  was in using verb tense with total of 61 errors. Meanwhile, the lowest frequency of item errors were in using adverb and adjective with total of 6 errors. Total of the errors was 204.
Simile in Harry Potter and The Chamber of Secrets
Authors: Siregar Sri Rahmadhani , Pane Widyanra
Published: November 2022

This research focused on simile analysis and meaning on Harry Potter and The Chamber of Secrets novel. Simile is a figurative language that makes a comparison, showing similarities between two different things. Qualitative research is used in conducting this research. The result of the research has found 55 sentences of Simile on Harry Potter and The Chamber of Secrets from chapter one up to chapter nine. The author used Simile to describe emotion of characters, to explain circumstances and to raise the interesting impression in the novel.
Students’ Reading Comprehension in Descriptive Text
Authors: Siregar Walidah Sofyan , Harida Eka Sustri
Published: November 2022

This research is discussing about the students’ reading comprehension of the second year MTs.Muhammadiyah 22 Padangsidimpuan. This research employed descriptive quantitative  research. Based on the result of the research, researcher got the description of the data was found that mean score was 56.76. It means that the students’ reading comprehension of the second year MTs.Muhammadiyah 22 Padangsidimpuan was categorized into enough ability. Then, from the result of the hypothesis testing, the researcher found that Zcount =-3.57Ztable 0.3264. It means the hypothesis was rejected. Thus, the result of mean scores the students’ ability in enough ability and actually it should be accepted hypothesis, but based on the result of that score it is rejected. So, maybe there is a mistake in instrument or in calculation.
Quizizz's Augmented Reality (AR) Based Mathematics Digital Pocketbook Design Using GOLD (Guided, Organizing, Leaflet, Discovery) Learning Model
Authors: Pasaribu Feri Tiona , Ramalisa Yelli
Published: November 2022

This research was conducted with the aim of meeting the needs of students in learning in the 21st century, where both students and educators are required to have good skills in utilizing technology in the learning process, especially when conducting distance education. This study aims to produce a digital pocket book based on Augmented Reality (AR) assisted by quizizz using the GOLD (Guided, Organizing, Leaflet, Discovery) learning model. This research is a development research that uses 4-D models (Four-D Models). Which consists of 4 stages of development, namely, the definition stage (define), the planning stage (Design), the development stage (develop), and the dissemination stage (Disseminate). The results of this study indicate that the product produces a useful pocket book. With a pocket book quality level based on 3 criteria, namely: valid and practical. From the research results obtained: 1) the percentage of pocket book validity from material experts 88% (very valid) and from design experts 87.6% (very valid), 2) the percentage of pocket book practicality by educators 88.75% (very practical) and by students 88, 8% (very practical). This research is still limited to testing the validity and practicality of digital pocket book.
Guru Profesional Abad XXI
Authors: Hasratuddin Hasratuddin
Published: November 2022

Education through learning with heart is an effort to humanize humans. When human behavior today does not show like a caliph who maintains peace in life, such as having shortcuts which deemed appropriate, then the education and teaching system needs to be reformed. A learning model that forms an ability to think logically, critically, creatively, obediently or consistently and fosters self-confidence and character is student-centered learning which includes constructive, interactive and reflective stages.
Pengembangan Buku Ajar Statistik Menggunakan Aplikasi SPSS sebagai Self-¬Education Mahasiswa
Authors: Sufri Sufri , Pasaribu Feri Tiona
Published: November 2022

The purpose of this research is to produce statistical textbooks using the SPSS (Statistical Product and Service Solution) application as self-education for students who meet the criteria of validity, practicality and effectiveness. This research is a development research that uses the ADDIE development model which implements an Analyze, Design, Develop, Implement, and Evaluate stage. The results obtained in this study are the quality of textbook development results from the results of material validation analysis with a percentage of 90%, design validation analysis with a percentage of 88.9% fulfilling very valid criteria. The results of the questionnaire analysis show that the textbook meets the very practical criteria. Based on the results of the analysis of the lecturer assessment questionnaire with a percentage of 90%, the results of the small group trial questionnaire analysis with a percentage of 79.50%. Thus, statistical textbooks using the SPSS (Statistical Product and Service Solution) application meet the valid and practical criteria.
Studi Penelusuran Alumni Prodi Tadris/Pendidikan Matematika IAIN Padangsidimpuan
Authors: Harahap Deswinda , Suparni Suparni
Published: November 2022

The background of this research is the writer's curiosity to the Graduates of Mathematics department at IAIN Padangsidimpuan. This article will describe the competencies of graduates of Mathematics department after they work. This article will also describe whether the Mathematics department has been able to prepare graduates' competencies in facing the challenges of the job market. The results of this study indicate that 95% of graduates are already working. Most of the graduates work in the education sector as mathematics teachers at various levels of public and private schools. It can be said that the place where they work is in accordance with their skill background. However, many of them still receive a very low salaries. Many of Ther salaries are under one million. For them, it does not matter, the most important thing for them is  they can work and they can apply their skills. Most of them are not too long to get the first job after graduated their studi, because before they graduate from their collage, they have started to look  for a job.
Pengaruh Pendekatan Matematika Realistik terhadap Minat Belajar Mahasiswa Tadris/Pendidikan Matematika pada Saat Pandemi Covid-19
Authors: Sari Lili Nur Indah
Published: November 2022

The purpose of this study was to see the effect of the Realistic Mathematics Approach on student interest in learning during the covid-19 pandemic. This research is a quasi-experimental research (quasi-experimental) conducted at the Padangsidimpuan State Islamic Institute, Faculty of Tarbiyah and Teacher Training, Tadris/Mathematics Education Study Program T.A 2019/2020. The conclusion from the questionnaire results obtained from students, the average score of student interest in learning who was treated with the Realistic Mathematics Approach was better than the average score of student interest in learning who was treated with the Conventional Approach. The average score of students who were treated with a realistic mathematical approach was 50.03, while the average score of students who were treated with the Conventional Approach was 41.73. In the calculation of the t test, the t value was obtained at a significance level of 0.151 0.05 so it can be concluded that there is an effect of a realistic mathematical approach on the learning interest of Tadris/Mathematics Education students during the covid-19 pandemic.
Pengaruh Penerapan Model Pembelajaran Kooperatif Tipe Roundtable terhadap Hasil Belajar Matematika
Authors: Anjarwati Eka , Suparni Suparni , Siregar Rahma Hayati
Published: November 2022

This research is motivated by the lowlearning outcomes of students, because the learning process at school still uses conventional learning models. Mathematics learning tends to be teacher-centered, resulting in students being less active in the learning process. Therefore, the researchers conducted research on the Round Table type of cooperative learning model that can affect students mathmatics learning outcomes.The formulation of the problem in this study is whether there is a significant influence of the Round Table type of coopetive learning model on students mathematics learning outcomes in the trigonometry material of Tenth Graders of SMA Negeri 2 Padang Bolak. The purpose of this study was to determine the significant influence of the Round Table type of coopetive learning model on students mathematics learning outcomes in the trigonometry material of Tenth Graders of SMA Negeri 2 Padang Bolak.This research is a quantitative study using experimental methods with the research design is non random contol group pre test post test design. The population in this study were Tenth Grade of SMA Negeri 2 Padang Bolak which consisted of three classes with a total of 79 students. The sampel in the experimental class that was given treatment amounted to 27 students and the control class that was not given treatment amounted to 25 students. Data processing and data analysis was carried out using the T-test.The result of the T-test obtainedthe average value of the experimental clas after the Round Table type of coopetive learning model was applied to the results of the pre test to the post test, which was 68,89 to 75,741. While in the control class the results of the pre test to the post test, which was 65 to 71,8. Based on the results of hypothesis testing obtained thitung ttabel (2,1758 2,008) with a significance level 5% and dk = 50, then H0 is rejected and Ha is accepted. Thus, it can be concluded that there is a significant influence of the Round Table type of coopetive learning model on students mathematics learning outcomes in the trigonometry material of Tenth Graders of SMA Negeri 2 Padang Bolak.
PERSEPSI MAHASISWA IAIN PADANGSIDIMPUAN TERHADAP PEMBELAJARAN ONLINE DI ERA PANDEMI COVID-19
Authors: Lubis Maulana Arafat , Marina Nisha , Azizan Nashran , Firdaus Fery Muhamad
Published: November 2022

Many impacts occurred when the COVID-19 pandemic occurred to disturb all humans on earth. The unrest came from students. One of the student concerns was that learning was carried out online. This case is the basis of the research. The research objective was to explore student difficulties during online learning during the COVID-19 period, the application used during online learning during the COVID-19 period, and the student's response to online learning during COVID-19. This study uses a qualitative method through a case study approach. The research was conducted at IAIN Padangsidimpuan. The informants in this study were 37 PGMI students from 2016-2019. Data collection using unstructured-planned interviews. The research procedure refers to the Creswell model. Data analysis used ATLAS.ti version 8 software. The results of this study obtained information from informants that students experienced many difficulties during online learning during the COVID-19 period, such as the high cost of buying data packages, the problem of internet signals and the exposure of less understood lecturers' material. During online learning, the teleconference application often used is google meet, while the social media that is always used is WhatsApp. So, from the conscience of each informant, they hoped that the learning process would not be thoroughly carried out online to reduce costs for buying internet packages or learning to be carried out face-to-face again on the condition that they adhere to health protocols.
IMPLEMENTASI TEORI BELAJAR SOSIAL ALBERT BANDURA PADA KURIKULUM DARURAT COVID-19
Authors: Azizah Umniyatul , Hermawan Acep Heris , Erihadiana Mohamad
Published: November 2022

Di tengah-tengah masa pandemi Covid-19 ini, tentulah semua orang termasukpendidik memikirkan cara agar bisa beraktivitas seperti biasa, mengajar dan tetapterkoneksi dengan pserta didik, dengan menggunakan internet, pembelajaran jarakjauhpun harus dilakukan menggunakan teori belajar seperti teori belajar AlbertBandura, untuk itu untuk memunculkan berbagai jenis pembelajaran menggunakanjaringan internet dengan aksebilitas, konektivitas dan fleksibelitas. Penelitian inibertujuan untuk mengkaji komponen kompetensi prioritas yang mana dirasa pentingdan bagaimana hubungan antar komponen tersebut. Metode penelitian yangdigunakan adalah metode kuantitatif dan kualitatif. Subjek penelitian 32 orang (17Laki-laki dan 15 Perempuan). Instrumen yang digunakan ialah daftar cek dan matrikpertanyaan triangulasi. Penelitan ini menyimpulkan bahwa kompetensi ScienceTechnology Engineering and Math (STEM), produk dan karakter yang bervariasidan hubungan STEM dan karakter lebih kuat daripada komponen produk.
KONSEP MANUSIA BERDASARKAN TINJAUAN FILSAFAT (TELAAH ASPEK ONTOLOGI, EPISTEMOLOGI DAN AKSIOLOGI MANUSIA)
Authors: Hayati Nursri
Published: November 2022

AbstracHumans are the most perfect creatures  that Allah was created  from the others. That's perfection make   humans take the mandate as khalifah fil ardh.  This paper examine humans with philosophy approach. The meaning of humans with philosophical approach can be done by examining humans from the ontology, epistemology, axiology aspect.  Ontology concerns the science of being or the science that discuss the nature of the existence something. Epistemology concerns about method, source to find the science. So, human epistemology discuss about How the process of human creation as well as human source. Axiology concerns about value, uses and function. So, human axiology discuss about purpose and function of human creation.Keyword: human; approach; phylosophy. AbstrakManusia adalah makhluk yang paling sempurna Allah ciptakan dibandingkan dengan makhluk hidup lainnya. Kesempurnaan tersebut menjadikan manusia mengemban amanah sebagai khalifah fil ardh. Tulisan ini mengkaji manusia dengan pendekatan filsafat. Pemaknaan manusia dengan pendekatan filsafat dapat dilakukan dengan mengkaji hakikat manusia dari sisi ontologi, epistemologi, dan aksiologi manusia. Ontologi, menyangkut ilmu tentang yang ada atau ilmu yang membahas tentang hakikat keberadaan sesuatu. Ontologi manusia berarti mengkaji tentang hakikat keberadaan manusia. Epistemologi, menyangkut metode, sumber,  dalam memperoleh sesuatu ilmu. Dalam pembahasan epistemologi manusia terkait tentang bagaimana proses penciptaan manusia serta sumber manusia. Aksiologi manusia, menyangkut nilai (value), manfaat, guna. Dalam pembahasan aksiologi manusia terkait tentang tujuan dan fungsi penciptaan manusia.Kata kunci: manusia; pendekatan filsafat.human; approach; phylosophy.
SEJARAH MADRASAH DI INDONESIA (PENDEKATAN SEJARAH DAN PERKEMBANGANNYA)
Authors: Daulay Muhammad Roihan
Published: November 2022

AbstrakPerkembangan madrasah di Indonesia sudah sangat pesat. Hal ini tidak terlepas dari perjalan sejarah madrasah yang cukup dinamis. Tujuan penelitian ini adalah untuk mengetahui sejarah perkembangan madrasah di Indonesia. Metode penelitian ini adalah kualitatif dengan menggunakan analisis yang bersifat deskriftif. Hasil penelitian menunjukkan bahwa berkembangnya madrasah di Indonesia memiliki kaitan dengan sejarah madrasah itu sendiri. Terjadinya peralihan dari pola konfensional ke moderen telah dimulai dari gerakan-gerakan yang muncul dari sudut internal maupun sudut eksternal. Dalam mengahadapi masa pandemi madrasah tetap menjaga protokol kesehatan yang diterapkan oleh pemerintah. Kata Kunci: sejarah; madrasah; indonesia.  AbstractThe development of madrasas in Indonesia has been very rapid. This is inseparable from the dynamic history of the madrasa. This study aims to determine the history of the development of madrasas in Indonesia. This research method is qualitative using descriptive analysis. The results show that the development of madrasas in Indonesia is related to madrasas' history. The transition from conventional to modern patterns has started with movements that appear from an internal as well as an external angle. In facing the pandemic, madrassas maintain the health protocols implemented by the government. Keywords: history; madrasa; Indonesia.
Performance Comparison of the SVM and SVM-PSO Algorithms for Heart Disease Prediction
Authors: Saputra Dedi , Dharmawan Weishky Steven , Irmayani Windi
Published: November 2022

Data analysis for datasets with very large dimensions, classification is needed to predict from large datasets, in this study compare a method for classifying large data where the data will be processed to obtain the desired data prediction information. In this study, the Support Vector Machine (SVM) is used to provide the classification results of an algorithm that will be compared with the incorporation of the Support Vector Machine (SVM) and Particle Swarm Optimization (PSO) where the test results will be compared with the SVM classification algorithm only as a comparison algorithm. better at predicting than data sets. SVM is used as a single algorithm to see different experimental results when SVM is combined with PSO. From the experiments carried out, SVM got an Accuracy value of 81.85% and an AUC value of 0.823 while SVM-PSO got an Accuracy value of 84.81% and an AUC value of 0.898.
Naturaleza jurídica de las criptomonedas a la luz de los pronunciamientos de soft law en Colombia
Authors: Ayala Aristizábal Álvaro
Published: November 2022

Las criptomonedas son unos instrumentos de un enorme crecimiento en el comercio nacional e internacional. El auge y crecimiento del mercado de criptomonedas ha generado un enorme reto regulatorio para los Estados, cuyo primer dilema consiste en la determinación de su naturaleza legal, la cual tiene una injerencia directa sobre su tratamiento regulatorio en términos de normas de protección al consumidor, normas de lavado de activos y financiación de terrorismo, tratamiento tributario, registro, supervisión de licencias e intermediarios (exchanges), y regulación de libros de registro digitalizados (DTL por sus siglas en inglés).
El presente documento analiza las características de las criptomonedas, así como una perspectiva comparada en el tratamiento legal que se les ha dado en Estados Unidos y los conceptos que sobre ellas han dado diferentes autoridades administrativas en Colombia, con miras a determinar cuál es la naturaleza jurídica de estos criptoactivos a la luz de estos pronunciamientos de soft law. En otros términos ¿son las criptomonedas un instrumento equiparable a la moneda legal de curso forzoso? ¿Son una divisa? ¿son un valor a la luz de la ley del mercado público de valores? ¿son un activo material? ¿son un activo inmaterial? o ¿son un activo de una naturaleza jurídica especial, esto es, un activo digital?
Junctional epidermolysis bullosa: genotype-phenotype correlations
Authors: Kubanov Alexey A. , Chikin Vadim V. , Karamova Arfenya E. , Monchakovskaya Ekaterina S.
Published: November 2022

Junctional epidermolysis bullosa most commonly results from mutations in the LAMA3, LAMB3, LAMC2, COL17A1, ITGA6 and ITGB4 genes. Junctional epidermolysis bullosa is characterized by clinical heterogeneity. To date, scientific findings allow to evaluate correlations between the severity of clinical manifestations and genetic defects underlying in the development of the disease. A systematic literature search was performed using PubMed and RSCI, and keywords including junctional epidermolysis bullosa, laminin 332, collagen XVII, 64 integrin. The review includes description of clinical findings of junctional epidermolysis bullosa, mutation location and types, its impact on protein production and functions. To evaluate the impact of gene mutation on protein functions, this review explores the structure and functions of lamina lucida components, including laminin 332, collagen XVII and 64 integrin, which are frequently associated with the development of junctional epidermolysis bullosa. The correlation between severe types of junctional epidermolysis bullosa and mutations resulting in premature stop codon generation and complete absence of protein expression has been described. Although, genotype-phenotype correlations should be analyzed carefully due to mechanisms which enable to improve protein expression.
Santé (dé)connectée ? Pistes de réflexions et expériences de l’altérité en contexte de santé connectée
Authors: BRAYET Elise
Published: November 2022

Les outils connectés d’accompagnement à la santé ont désormais rejoint nos techniques du corps. Pourtant vantés comme « partenaires de vie » dont l’intelligence des algorithmes et la précision des données générées suffiraient à l’auto-éducation corporelle de l’individu, où passe l’Autre dans cette relation biotechnique inédite ? Le corps connecté ne l’est-il qu’aux outils qui le mesurent ? À travers une série d’entretiens, nous voyons émerger des formes diverses de l’altérité. L’outil lui-même introduit des formes de subjectivités qui impactent l’utilisation. Par suite, les outils génèrent un Autre individu par l’altération de l’image de soi qu’ils permettent. Pour finir, loin de se détourner de toute relation, la santé connectée renouvelle l’écologie du sujet et appelle à des nouvelles configurations sociales et médicales.
RNA hydrolysis at mineral-water interfaces
Authors: Zhang Ke , Ho Kun-Pu , Chatterjee Anamika , Park Grace , Li Zhiyao , Catalano Jeffrey , Parker Kimberly
Published: November 2022

The adsorption of DNA at mineral-water interfaces is well-established to increase its persistence in soils and sediments; however, adsorbed RNA in similar environments degrades rapidly, in some cases outpacing solution-phase degradation occurring over hours to days. Herein, we elucidate a novel abiotic mechanism by which RNA, but not DNA, degrades upon adsorption to surfaces of iron (oxyhydr)oxides such as goethite (α-FeOOH) that are abundant in soils and sediments. Upon adsorption to goethite, both single-stranded and double-stranded RNA hydrolyzed on the timescale of hours under environmentally relevant physicochemical conditions. The reaction products were consistent with iron present in goethite acting as a Lewis acid to accelerate non-selective hydrolysis of phosphodiester bonds comprising the RNA backbone. In contrast to well-established acid- or base-catalyzed RNA hydrolysis in solution, mineral-catalyzed hydrolysis was fastest at circumneutral pH, which allowed for both sufficient RNA adsorption and hydroxide concentration. We further confirmed that contact of the RNA with the mineral surface is necessary for hydrolysis to occur by demonstrating RNA degradation was inhibited by compact RNA conformation at elevated ionic strength and competitive adsorption with orthophosphate and organic matter. In addition to goethite, we observed RNA hydrolysis was also catalyzed by hematite (α-Fe2O3), but not by aluminum-containing minerals (e.g., montmorillonite). Given the extensive adsorption of nucleic acids to environmental surfaces, we anticipate previously overlooked mineral-catalyzed hydrolysis of RNA may be prevalent particularly in iron-rich soils and sediments, which must be considered across biogeochemical applications of nucleic acid analysis in environmental systems.
Algorithm Selection for Protein-Ligand Docking: A Case Study on ACE with AutoDock
Authors: Chen Tian-Lai , Zhou Huiyuan , Shu Xiwen , Beckford Floyd , Misir Mustafa
Published: November 2022

The present study investigates the use of algorithm selection for automatically choosing an algorithm for any given protein-ligand docking task. In drug discovery and design process, conceptualizing protein-ligand binding is a major problem. Targeting this problem through computational methods is beneficial in order to substantially reduce the resource and time requirements for the overall drug development process. One way of addressing protein-ligand docking is to model it as a search and optimization problem. There have been a variety of algorithmic solutions in this respect. However, there is no ultimate algorithm that can efficiently tackle this problem, both in terms of protein-ligand docking quality and speed. This argument motivates devising new algorithms, tailored to the particular protein-ligand docking scenarios. To this end, this paper reports a machine learning-based approach for improved and robust docking performance. The proposed set-up is fully automated, operating without any expert opinion or involvement both on the problem and algorithm aspects. As a case study, an empirical analysis was performed on a well-known protein, Human Angiotensin-Converting Enzyme (ACE), with 1428 ligands. For general applicability, AutoDock 4.2 was used as the docking platform. The candidate algorithms are also taken from AutoDock 4.2. Twenty-eight distinctly configured Lamarckian-Genetic Algorithm (LGA) are chosen to build an algorithm set. ALORS which is a recommender system-based algorithm selection system was preferred for automating the selection from those LGA variants on a per-instance basis. For realizing this selection automation, molecular descriptors and substructure fingerprints were employed as the features characterizing each target protein-ligand docking instance. The computational results revealed that algorithm selection outperforms all those candidate algorithms. Further assessment is reported on the algorithms space, discussing the contributions of LGA’s parameters. As it pertains to protein-ligand docking, the contributions of the aforementioned features are examined, which shed light on the critical features affecting the docking performance.
Accurate quantum-chemical fragmentation calculations for ion-water clusters with the density-based many-body expansion
Authors: Schürmann Stefanie , Vornweg Johannes R. , Wolter Mario , Jacob Christoph R.
Published: November 2022

The many-body expansion (MBE) provides an attractive fragmentation method for the efficient quantum-chemical treatment of molecular clusters. However, its convergence with the many-body order is generally slow for molecular clusters that exhibit large intermolecular polarization effects. Ion--water clusters are thus a particularly challenging test case for quantum-chemical fragmentation methods based on the MBE. Here, we assess the accuracy of both the conventional, energy-based MBE and the recently developed density-based MBE [Schmitt-Monreal and Jacob, Int. J. Quantum Chem, 120, e26228 (2020)] for ion--water clusters. As test cases, we consider hydrated Ca^2+, F^-, OH^-, and H3O^+, and compare both total interaction energies and the relative interaction energies of different structural isomers. We show that an embedded density-based two-body expansion yields highly accurate results compared to supermolecular calculations. Already at the two-body level, the density-based MBE clearly outperforms a conventional, energy-based embedded three-body expansion. We compare different embedding schemes and find that a relaxed frozen-density embedding potential yields the most accurate results. This opens the door to accurate and efficient quantum-chemical calculations for large ion--water clusters as well as condensed-phase systems.
Overcoming the Interfacial Challenges of LiFePO4 in Inorganic All-Solid-State Batteries
Authors: Cronk Ashley , Chen Yu-Ting , Deysher Grayson , Ham So-Yeon , Yang Hedi , Ridley Phillip , Sayahpour Baharak , Nguyen Long Hoang Bao , Oh Jin An Sam , Jang Jihyun , Tan Darren H.S. , Meng Ying Shirley
Published: November 2022

All-solid-state batteries (ASSBs) are one of the most promising systems to enable long-lasting and thermally resilient next-generation energy storage. Ideally, these systems should utilize low-cost resources with reduced reliance on critical materials. Pursuing cobalt- and nickel-free chemistries, like LiFePO4 (LFP), is a promising strategy. Morphological features of LFP essential for improved electrochemical performance, are highlighted to elucidate the interfacial challenges when implemented in ASSBs, since adoption in inorganic ASSBs have yet to be reported. In this work, the compatibility of LFP with two types of solid-state electrolytes, Li6PS5Cl (LPSCl) and Li2ZrCl6 (LZC), are investigated. The potential existence of oxidative decomposition products is probed using a combination of structural, electrochemical, and spectroscopic analyses. Bulk and interfacial characterization reveal that the sulfide-based electrolyte, LPSCl decomposes into insulative products, and electrochemical impedance spectroscopy is used to quantify the resulting impedance growth. However, through utilization of the chloride-based electrolyte, LZC, high-rate and stable electrochemical performance is achieved at room temperature.
Expedient Access to Optically Pure Atropisomeric-NHC Ruthenium Complexes for (Z)-Selective Asymmetric Ring- Opening Cross Metathesis
Authors: Morvan Jennifer , Bouëtard Dylan , Kong Lingyu , Chou Yajie , Vives Thomas , Albalat Muriel , Roisnel Thierry , Crévisy Christophe , Nava Paola , Humbel Stéphane , Vanthuyne Nicolas , Clavier Hervé , Mauduit Marc
Published: November 2022

Optically pure ruthenium complexes containing atropisomerically stable N-Heterocyclic Carbene (NHC) ligands are described. Isolated in excellent optical purities (up >99.5% ee) by a successful preparative HPLC resolution on a chiral stationary phase, these catalysts demonstrate excellent enantioselectivities in asymmetric ring-opening-cross metathesis (AROCM) (up to 97:3 er). Additionally, an optically pure Z-stereoselective catechodithiolated complex was also synthesized in nearly quantitative yield (or in-situ generated), furnishing enantioenriched Z-AROCM products in excellent 99/1 Z/E ratio and high enantioselectivity (up to 96.5:3.5 er).
A Novel Scaffold for Nitric Oxide Photo-Releasers based on Meso-Aminomethyl-BODIPY
Authors: Panfilov Mikhail , Karogodina Tatyana , Sibiryakova Anastasiya , Tretyakova Irina , Vorob’ev Alexey , Moskalensky Alexander
Published: November 2022

Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Its short half-life and local action impede direct application in medicine because highly targeted NO-delivery systems are required. Light-controllable NO releasers are promising for the development of smart therapies. Here we present novel simply prepared meso-aminomethyl BODIPY dyes containing N-Nitroso moiety and show the photoinduced generation of NO in a solution. As an example of NO-mediated effects, we demonstrate efficient light-dependent inhibition of platelet activation in vitro. We also show that some compounds could additionally generate singlet oxygen, which is promising for the photodynamic therapy. The presented compounds could serve as the basis for the development of novel hybrid therapeutic methods.