bluuebunny/crossref_metadata_2025 huggingface dataset:
Nominalization in Priyanka Chopra’s Selected Speeches
Authors: Pasaribu Sonia Margareta , Setia Eddy , Putri Dian Marisha
Published: May 2023

This study aims to find out types of nominalization used in Priyanka Chopra’s selected speeches and the realizations. The selected speeches were taken from written sources and videos on the internet consisting of three speeches. This research used a descriptive qualitative method by applying theory of nominalization in Systemic Functional Linguistics by Quirk et al. The data collection techniques were conducted by applying a documentation method. The documents used to support this study were in the form of videos and transcriptions of the speeches on the internet. The results showed that not all the three types of nominalization were used in the three selected speeches. The nominalization with the gerundive noun type was used in all the three selected speeches. There were 6 gerundive nouns (14.6%) in the first speech, 7 gerundive nouns (25%) in the second speech, and 4 gerundive nouns (21%) in the third speech. The nominalization with verbal noun type was only used 1 (2.4%) among the three selected speeches which was in the first speech. Meanwhile, the deverbal noun type was used most in all the three selected speeches. There were 34 deverbal nouns (83%) in the first speech, 21 deverbal nouns (75%) in the second speech, and 15 deverbal nouns (79%) in the third speech. The nominalizations were realized by suffixations and conversions. The nominalizations were formed in the presence of the suffixes –dom, -er, –ing, -ion, -ity, -ment, and -or. Also, they were formed by conversion, such as the nouns care, cause, experience, and waste.
Lexical Errors Made by Instagram Machine Translation in Translating the Account of “CNN Indonesia” News Article
Authors: Nadilla Raihan , Lubis Syahron
Published: May 2023

This study aims to depict the types of errors made by Instagram Machine Translation and to find out the most dominant types of lexical errors made by Instagram Machine Translation on ‘CNN Indonesia’ Instagram account. The design of this research was qualitative design. The data were in words, phrases, and sentences that contained lexical errors made by Instagram Machine Translation on the “CNNIndonesia” Instagram account. The data were taken by running an Instagram in one account of various captions related to the lexical errors of the study object. The data were collected through stages: finding out and determining, classifying, and separating the words, phrases, and sentences that contained lexical errors made Instagram Machine Translation on the “CNN Indonesia” Instagram account. The techniques of analysis data researcher translated the captions using Instagram machine translation and then the translation result is compared to the source language. The next step is to examine the lexical errors produced by Instagram machine translation. The research result shows that the types of lexical errors made by Instagram Machine Translation on the “CNN Indonesia” Instagram account based on the error categories theory by Vilar et al founds are: 4 missing errors, 10 incorrect words, and 8 unknown words. All errors indicated that Instagram machine translation could not represent the target language in the “CNN Indonesia” Instagram account. The users of Instagram need to filter every translation that is translated by Instagram machine translation before receiving it as information.
ФОРМУВАННЯ ПРАЦЕОХОРОННОЇ КОМПЕТЕНТНОСТІ В ПРОЦЕСІ ПРОФЕСІЙНОЇ ПІДГОТОВКИ ФАХІВЦІВ МЕХАНІЧНОЇ ІНЖЕНЕРІЇ
Authors: Кобилянський Олександр , Дембіцька Софія
Published: May 2023

Актуальність: формування мотивації працівників до дотримання безпеки безпосередньо впливає на зменшення виробничого травматизму та підвищення доходу підприємств. Відтак, підготовка фахівців механічної інженерії до працеохоронної професійної діяльності з метою забезпечення її ефективності має відбуватися на етапі навчання студентів у ЗВО.
Мета: полягає у визначенні змісту працеохоронної компетентності фахівців механічної інженерії як невідємної складової професійної підготовки та окреслені ефективних шляхів її формування.
Методи: теоретичні (аналіз стандартів вищої освіти, публікацій, що відображають проблему дослідження, узагальнення кращого вітчизняного та зарубіжного педагогічного досвіду щодо підготовки фахівців технічних спеціальностей до працеохоронної професійної діяльності); емпіричні (анкетування, опитування для з’ясування рівня зацікавленості та активності студентів у набутті працеохоронних знань, умінь та навичок; спостереження за навчальним процесом; опитування експертів).
Результати: проаналізовано сучасні підходи до управління ризиками підприємства, уточнено зміст ризик-орієнтованого мислення; на підставі ризик-орієнтованого підходу означено зміст поняття «працеохоронна компетентність»; визначено та схарактеризовано шляхи формування працеохоронної компетентності майбутніх фахівців механічної інженерії.
Висновки: визначення змісту працеохоронної компетентності майбутніх фахівців механічної інженерії охоплювало аналіз теоретичних студій, присвячених особливостям професійної підготовки фахівців машинобудівної галузі та специфіці ризик-орієнтованого мислення (відповідно до ДСТУ ISO 9001:2015), а також вивчення умов професійної діяльності працівників на кожному етапі створення та виготовлення продукції машинобудівної галузі.
Історична роль особистості у державотворчих процесах доби УНР : зб. матеріалів наук. круглого столу
Authors:   Національний університет ", Єфремова Н. В. ,   Одеська юридична академія", Іванійчук Т. Ю.
Published: May 2023

До збірника матеріалів наукового круглого столу «Історична роль особистості у державотворчих процесах доби УНР» увійшли результати історико-правових досліджень важливих питань з історії українського державотворення доби Української Держави за П. Скоропадського. Матеріали представлені в авторській редакції. Відповідальність за зміст матеріалів, точність наведених фактів, цитат, посилань на джерела, достовірність іншої інформації та за додержання норм авторського права несуть автори.
Histopathological analysis of the liver in hypercholesterolemia rats treated with Dillenia serrata fruits
Authors: Tien  , Utami Tri Wistya , Aritrina Pranita , Kardin Laode , Sukurni  , Syarifin Andi Noor Kholidha
Published: May 2023

Background: Dillenia serrata (locally known as singi) is a natural product with the potential to improve liver function in hypercholesterolemia, due to anticholesterol and antioxidant properties.
Objective: This study aimed to investigate the effect of D. serrata on the histopathological features of rat livers induced by a high-fat diet.
Methods: This study used a quasi-experimental in vivo with a post-test-only control group design. Rats were divided into four groups: normal, high-fat diet, as well as D. serrata, and simvastatin treatment. Hypercholesterolemia was induced by a high-fat diet for two weeks. Rat liver tissues were analyzed histologically using Hematoxylin-Eosin (HE) staining, and were observed under a light microscope at 40x magnification in five wide fields of view.
Results: The high-fat diet group had the most adipose cells, while the D. serrata group had the least. Statistical analysis demonstrated a significant difference between the high-fat diet group and the other groups (p < 0.05). Interestingly, no significant difference between the D. serrata group and either the normal or simvastatin group (p > 0.05), suggesting the treatment of fruit may restore liver function comparable to normal and simvastatin group.
Conclusion: The D. serrata fruit reduces the number of fat cells in the histopathology of rats induced with the high-fat diet.
Condominium Townhouse Investment
Authors: Wakil Gulraze , Petruska Karin
Published: May 2023

This accounting case involves the evaluation of various alternatives based on a real-life personal property investment. The Condominium Townhouse Investment (CTI) case uses introductory management accounting concepts and analyses to introduce students to the case method of learning. The main concepts reinforced are relevant costs and revenues, including diﬀerentiating between opportunity and sunk costs. Students are not only asked to deﬁne and identify these items, but to consider choices centered on the decision alternatives in their role as accountants in public practice. This case is especially valuable because it oﬀers students the chance to become engaged in an analysis and decision-making situation that they can relate to both personally and professionally because, one day, they themselves are likely to become involved in a home ownership decision. The case focuses on real estate as a personal business investment, and requires both qualitative and quantitative analysis, with more emphasis on the qualitative aspect. In addition, the teaching notes include methods and strategies for students to use in an introductory managerial accounting class or level-1 MBA class. 
Conservatism, Accrual Persistence Asymmetry, and Stock Returns
Authors: Wakil Gulraze , Alam Pervaiz
Published: May 2023

This paper investigates accounting conservatism’s effects on accrual persistence and accrual-related future stock returns. We find conservatism significantly increases accrual persistence and accrual-related future stock returns and more so in high accrual firms. We attribute this to conservatism’s reliability and verifiability requirements. However, the effect is statistically insignificant using only low accrual firms. Therefore, conservatism’s effects on accruals depend on their magnitude, i.e., asymmetrically. Moreover, increases in persistence and stock returns related to conservatism in high accrual firms also exists in recent years during which prior literature has shown the accruals anomaly to have diminished to insignificant levels. Our paper will be of interest to investors because markets do not fully capture how accounting conservatism affects accruals and also to auditors, lenders, and standard setters since collectively our paper finds accounting conservatism to be a positive trait for financial reporting.
Pengaruh Modifikasi Media Penyulingan Dan Waktu Penampung Nira Bunga Lontar Jantan (Borassus Flabellifer L.) Terhadap Kualitas Produk Sopi Timor (Tua nakaf).
Authors: Saba Agu Yakobus Pffeferius Edvent , Ceunfin Syprianus , Neno Yohanes
Published: May 2023

Sopi merupakan minuman beralkohol hasil penyulingan terhadap Nira Lontar. Bagi masyarakat adat dawan Sopi adalah minuman tradisional simbol budaya dan pengikat tali silaturahmi antar anggota keluarga misalkan pembuka pembicaraan adat dan atau media penyelesaian perselisihan. Persoalan yang terjadi di masyarakat saat ini adalah masyarakata masih cenderung menerapkan proses penyulingan secara konvensional atau warisan leluhur, dengan membutuhkan waktu yang relatif lebih lama untuk menghasilkan minuman sopi dengan kwalitas terbaik. Shok merupakan media yang digunakan dari bambu yang digunakan untuk penyulingan sopi. Rumusan masalah dalam penelitian ini adalah i) Bagaimana pengaruh modifikasi media penyulingan (tinggi shok) terhadap kualitas produk sopi Timor, ii) Bagaimana kualitas produk sopi Timor berdasarkan lama waktu penampung nira 24 jam dan 12 jam bunga lontar. Penelitian ini bertujuan untuk mengetahui pengaruh modifikasi media penyulingan terhadap kualitas produk sopi Timor. Untuk mengetahui kualitas produk Sopi Timor berdasarkan lama waktu penampung nira lontar. Penelitian ini telah dilaksanakan di Desa Lanaus pada bulan September sampai dengan Oktober 2020. Nira lontar yang digunakan sebagai bahan baku penelitian, disadap dari pohon lontar jantan yang tumbuh disekitar perkebunan dan hutan rakyat di Desa Lanaus, Kecamatan Insana Tengah, Kabupaten TTU-NTT. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) pola faktorial, yang terdiri atas 2 faktor. Hasil penelitian menunjukan tidak terjadi interaksi antara perlakuan tinggi shok dan lama penampungan nira terhadap parameter kadar alkohol nira, derajat keasaman nira, padatan terlarut nira, kadar alkohol sopi, derajat keasaman sopi, dan padatan terlarut sopi. Perlakuan tinggi shok sangat berpengaruh terhadap kadar alkohol sopi hal ini di tunjukkan dengan nilai kadar alkohol sopi pada waktu penyulingan 12 jam sore pada perlakuan tinggi shok 3 meter dimana hasil mencapai kadar alkohol 48.33 %. Perlakuan lama penampung nira berpengaruh nyata terhadap kualitas sopi hal ini di tunjukkan dengan lama penyimpanan 12 jam pagi memberikan nilai kadar alkohol nira, dan derajat keasaman nira tertinggi sedangkan pada padatan terlarut nira perlakuan 12 jam sore memberikan nilai padatan terlarut tertinggi. Namun pada parameter kadar alkohol sopi, derajat keasaman sopi serta padatan terlarut sopi lama penampung terbaik adalah perlakuan lama penampung 12 jam sore (tinggi shok 3 meter). Berdasarkan penelitian yang telah dilakukan maka penulis menyarankan untuk mendapatkan penyulingan sopi yang berkualitas sebaiknya perlunya waktu penampung nira selama 12 jam sore dan dengan tinggi shok 3 meter.
The Urban Management of Secondary Raw Materials in the Light of Commons Theory
Authors: Franca Simone
Published: May 2023

This paper intends to verify to what extent the theory of the commons and, in particular, the theory of shared administration can give useful suggestions in dealing with the problems of managing secondary raw materials, in a perspective compatible to the paradigm of circular economy. To this end, the discussion will be divided into three parts. First, the evolution of the regulatory framework for by-products will be analyzed in order to identify whether there is room for bottom-up mechanisms of by-product care. Second, we will examine to what extent by-products can be configured as commons, and what implications this has in the light of the Italian debate on commons. Third, the theoretical and practical scope of the theory of shared administration in the management of secondary raw materials will be analyzed. The analysis conveys the importance of embracing the commons theory and practice in order to concretely implement the circular economy paradigm with regard to the use of byproducts.
De profesor normalista a ideólogo socialista: José de Jesús Barrón Zúñiga y sus aportaciones en el periodo cardenista (1934-1940)
Authors: Trujillo Holguín Jesús Adolfo , Pérez Piñón Francisco Alberto , Liddiard Cáredenas Stefany
Published: May 2023

Entre las figuras más representativas del magisterio del siglo XX destaca un grupo de profesores normalistas que fueron artífices de proyectos políticos y educativos que dejaron profunda huella en la sociedad y que actualmente son emblemáticos de la etapa socialista de la educación en Chihuahua (1934-1940). El presente trabajo de investigación se ocupa de rescatar la vida y obra de José de Jesús Barrón Zúñiga, a quien su ideología política, origen proletario y espíritu revolucionario lo llevaron a transitar por una vida de múltiples facetas: la de líder estudiantil, joven maestro e ideólogo consolidado. El trabajo forma parte del proyecto “Figuras del magisterio chihuahuense”, el cual busca rescatar las biografías de las y los maestros cuyas aportaciones marcaron el rumbo al sistema educativo en el estado de Chihuahua en diferentes etapas y momentos históricos. La metodología para el desarrollo de la investigación se inscribe en los estudios biográficos, caracterizados por incursionar en la vida de personajes (vivos o muertos) que tienen relevancia para una temática en específico, para lo cual se recurre a fuentes primarias localizadas en el Archivo Histórico Municipal y en el Archivo Histórico de la Universidad Autónoma de Chihuahua. Adicionalmente se incorpora información de testimonios orales que se obtuvieron a partir de entrevistas con familiares y amigos del personaje en cuestión. La trascendencia de este trabajo se encuentra en el hecho de rescatar las aportaciones educativas del personaje, ya que su obra es desconocida por las actuales generaciones...
¿Por qué publicar los resultados de una investigación educativa?
Authors: Sánchez Luján Bertha Ivonne
Published: May 2023

En los años recientes, las revistas académicas o científicas han sido el medio más utilizado para dar a conocer los resultados de las investigaciones que se llevan a cabo en el ámbito educativo. Una de estas revistas es RECIE, que poco a poco se ha posicionado como un vehículo para dar a conocer aquello que los grupos de investigación, los académicos y sus estudiantes están produciendo en formación de profesores, diseño e implementación de estrategias didácticas, revisión de planes y programas de estudios, análisis de factibilidad para la apertura de nuevas carreras, el impacto que las políticas educativas tienen en los actores de la educación, y todos aquellos temas que impactan en el proceso educativo.
Editorial
Authors: Drachen Anders
Published: May 2023

The International Journal of Role-Playing is a response to a growing need for a place where the varied and wonderful fields of role-playing research and development, covering academia, the industry, and the arts, can exchange knowledge and research, form networks and communicate.
Seeking Fulfillment: Comparing Role-Play in Table-top Gaming and World of Warcraft
Authors: Pittman Jason , Paul Christopher
Published: May 2023

In the midst of the massive growth in the numbers of people participating in massively multiplayer online role-playing games (MMORPGs), study of the role-playing within these games is increasingly marginalized, as role-playing servers are developed to segregate player bases and as scholars increasingly focus on the non-role-playing aspects of online game play. We seek toaddress that disconnection by studying relative levels of fulfillment and frequency of tabletop and online role-playing for World of Warcraft (WoW) subscribers.

Finally, demographic information taken from the players themselves aids in guiding future research about which type of role-play gamers are more likely to participate in and find fulfilling. By looking at the age, location, and gender of players the relative merits of each type of role-playing is discussed, pointing to strategies to capitalize on the strengths and minimize the failings of each venue for role-playing. This study aids both the online and offline gaming industry in better understanding their target role-playing audiences, while providing a grounded study of avid role-players to support analysis of game dynamics.
Editorial - Transformative Play Seminar 2022: Education, Meaning Making, and Personal Development
Authors: Bowman Sarah Lynne , White William J. , Torner Evan
Published: May 2023

Editorial - Transformative Play Seminar 2022: Education, Meaning Making, and Personal Development
The Educational Role-Playing Game Design Matrix: Mapping Design Components onto Types of Education
Authors: Westborg Josefin
Published: May 2023

This article offers categories for understanding different facets of learning and role-playing games, including setting, purpose, framing, type of processing, and learning objectives. Types of games categorized include leisure, stand-alone educational RPGs, RPGs in education, and Educational RPGs.
Sadomasochist Role-Playing as Live-Action Role-Playing: A Trait-Descriptive Analysis
Authors: Harviainen J. Tuomas
Published: May 2023

This article describes sadomasochist role-playing which is physically performed by its participants. All sadomasochist activities have a role-playing component to them. It is a form of role-playing where people consensually take on dominant and submissive roles, for the purpose of inflicting things such as pain and humiliation, in order to create pleasure for all participants. In some cases, participants agree to emphasize those roles, or make them fetishistically attractive, by adding complexity and definitions to them, and then act them out in semi-scripted fantasy scenes. This paper examines that activity, commonly called “sadomasochistic role-play”, as opposed to the more generic “sadomasochism” of which it is only one facet.
Furthermore, the article compares this form of play with live-action role-playing (larp). Its main emphasis is on the question of how closely related the two activities are. To determine this, the article examines sadomasochist role-playing as being potentially a game, the question of its goal-orientation and the issue of whether or not it contains a character in the sense of a live-action role-playing character. Based on this process, it comes to the conclusion that sadomasochist role-playing is not a separate type of role-playing, but rather one kind of live-action role-playing.
As its theoretical framework, this text utilizes studies done on both live-action role-playing games and on sadomasochist role-playing. Reliable material on the latter being quite limited, descriptions have been gathered from both academic works and practical manuals. The data gained from these is further supported by interviews of practitioners with personal experience in playing sadomasochist fantasy scenes. This article has two key purposes: The research of a relatively understudied form of role-playing, and the building of bridges from that to live-action role-playing research.
Editorial
Authors: Harviainen J. Tuomas
Published: May 2023

Editorial for IJRP 5.
Enhancing Healthcare Simulations and Beyond: Immersion Theory and Practice
Authors: Bowman Sarah Lynne , Standiford Andhe
Published: May 2023

This paper synthesizes the different ways that players and theorists discuss immersion in role-playing games, establishing six major categories: immersion into activity, game, environment, narrative, character, and community. For the purposes of understanding typical modes of engagement, immersion concepts are considered alongside player motivation theories. Furthermore, this article applies these categories, which are drawn largely from game studies, to the field of health care simulation, categorizing specific practices within the simulation classroom according to types of immersion. The goal of this research is to enhance the understanding and design of simulation by appealing to multiple modes of immersion, which may assist in engaging a greater number of students. Diversifying the types of experiences within health care simulations in order to appeal to multiple modalities of immersion holds the potential to create more rich and layered experiential learning situations.
Meningkatkan Hasil Belajar Siswa Kelas VIIIB pada Mata Pelajaran PAI (Pendidikan Agama Islam) melalui Metode Make A Match di SMPN 11 Muaro Jambi
Authors: Ismianti Santi
Published: May 2023

penelitian ini bertujuan untuk melihat pengaruh hasil belajar siswa Kelas VIII B SMPN 11 Muaro Jambi pada Mata Pelajaran Pendidikan Agama Islam. Penelitian ini adalah penelitian tindak kelas (PTK) dengan menggunakan metode pembelajaran Make A Match. Penelitian ini menggunakan siklus model penelitian yang dimulai dengan tahap perencanaan, tindakan, pengamatan dan refleksi. Hasil pengamatan ini menunjukkan bahwa pada siklus 1 diketahui bahwa siswa yang tuntas 18 orang dengan rata-rata 71 dan pada siklus 2 mengalami peningkatan 31 orang tuntas dengan nilai rata-rata 87. Dengan menggunakan metode make a macth pada siklus 1 mencapai 53 % dan belum mencapai ketuntasan, sedangkan pada siklus 2 mengalami peningkatan mencapai 91 %.
Wujud Aspek Psikologis dalam Sajak Penyair Jambi Ari Setya Ardhi
Authors: Amral Sainil , Sumiharti Sumiharti
Published: May 2023

The purpose of this study is to describe  the form of conveying the psychological aspects of the psychiatric form contained in the poems of the Jambi poet Ari Setya Ardhi. Jambi poet means a poet who lives in the Jambi area, actively works, and always documents his rhymes in individual anthologies and joint anthologies. This research includes descriptive research with a content analysis approach to documents in the form of literary works. The data in this study are rhyme texts that refer to the psychological aspects of the psychiatric form of depression and the psychiatric form of anxiety. The results showed that in the poems of the Jambi poet Ari Setya Ardhi depression was identified through the use of sounds, word choices, complete text, typography, and the use of imagery
Multi-Dimensional Bisection Method in HIL Environment: Stability and Chatter Prediction in Turning
Authors: Béri Bence , Bachrathy Dániel , Stépán Gábor
Published: May 2023

In turning operations, the harmful small-amplitude but high-frequency chatter vibrations are identified in hardware-in-the-loop (HIL) experimental environment by means of the application of a multi-dimensional bisection method. The dummy workpiece clamped to the real main spindle is excited by contactless electromagnetic actuators and the response of the workpiece is detected by laser-based sensors. According to the present and the stored previous positions of the rotating workpiece, the desired cutting force characteristic along with the surface regeneration effect can be emulated by means of a high-performance real target computer. While the conventional experimental results in the HIL environment identify the stability limits of the cutting operation accurately only in a high-resolution grid of the technological parameters, the embedded bisection method reduces significantly both the size of the required grid and the time duration of the measurement by path following the boundaries of the linear loss of stability. Based on this technique, the experimental stability boundary of the emulated turning process is presented in a wide range of spindle speeds.
Infectious Complications After A Liver Transplant
Authors:   Director of Agrinio ICU, Thessaloniki, Greece, Consultant Anaesthesiologist-Intensivist, Thessaloniki, Greece, Michailidou Evangelia Michail , Katsanos Georgios ,   Assistant Professor of Surgery, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece, Antoniadis Nikolaos ,   Assistant Professor of Surgery, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece, Argiriadou Eleni ,   Associate Professor of Anaesthesiology – Cardioanaesthesiology, Department of Anesthesiology and Intensive Care, Aristotle University of Thessaloniki, Greece
Published: May 2023

Liver transplantation is a life-extending procedure for patients with end-stage liver disease (ESLD), post-transplant infections continue to be a leading cause of morbidity and mortality. Infection risk varies over time, with issues most commonly related to transplant surgery and nosocomial infections in the early post-transplant period. Because of the increased burden of immunosuppression, opportunistic infections become more common between 1 and 12 months post-transplant. As immunosuppression is reduced after 12 months, the risk of opportunistic infections decreases. Recipients are still vulnerable to community-acquired infections, and recurrent cholangitis may become an issue in those with chronic allograft dysfunction or recurrent cholestatic liver disease. This article will go over a strategy for dealing with infectious complications in the early, intermediate, and late stages following liver transplantation, with a focus on the most common infections as well as those of emerging concern.
TBE in France
Authors: Hansmann Yves , Velay Aurélie
Published: May 2023

The first human case of tick-borne encephalitis virus (TBEV) infection in France was reported in 1968 in Alsace, an eastern region next to the German border: a gamekeeper working in a forest near Strasbourg. Between 1970 and 1974, an extensive research survey confirmed the presence of TBEV in ticks and rodents in this French region. Eight percent of adult tick batches collected were infected (Ixodes ricinus) by the TBEV. Tick collection occurred in a forest near Strasbourg, the main city in the region. Nymphs were more rarely infected (1.6% of the collected lots). These data were confirmed in 2011 in Alsace in Guebwiller’s Valley, a middle altitude forest, with identification of western (European) subtype TBEV (TBEV-EU).
TBE in Kazakhstan
Authors: Dmitrovskiy Andrey
Published: May 2023

The first isolation of the TBEV in Kazakhstan was achieved in the Almaty region by M.P. Chumakov in 1941 (only one strain from one patient) during the expedition organized by the Central Institute of Epidemiology and Microbiology (Moscow). This is proof that the clinically well-described “spring-summer encephalitis” in the Almaty region was in fact TBE. Later, in 1943, 1944 and 1945 the TBEV was also isolated from additional patients by local scientists from the Institute of Epidemiology and Microbiology, Laboratory of Virology in Alma-Ata by Prof. E. I. Demikhovsky. Isolation had been accomplished from CSF samples up to 8 days of illness and also from brain tissue on day 12.
TBE in Ukraine
Authors: Nebogatkin Igor , Onishchuk Olga , Oleksandr Hnatiuk , Erber Wilhelm , Vuković-Janković Tamara
Published: May 2023

The available data indicate that infection with tick-borne encephalitis virus (TBEV) is the most common arbovirus infection in Ukraine. Natural TBE foci are mainly located in the Polissya territories (Volyn, Rivne, Zhytomyr, Kyiv, and the Chernigiv region), as well as the Pre-Carpathian and Trans–Carpathian regions; a highly intensive distribution of TBEV was also observed in the entire mountain forest zone of Crimea and in Volinskij.
TBE in Bosnia and Herzegovina
Authors: Erber Wilhelm , Vuković-Janković Tamara
Published: May 2023

Very limited information is available for Bosnia showing the occurrence of TBE.

Even though there have been some elder case reports in the northern parts of the country, including alimentary infections, details have not been published.
Chapter 14: TBE-Prevention: Vaccines and Immunoglobulins
Authors: Pöllabauer Eva-Maria , Kollaritsch Herwig
Published: May 2023

Worldwide there are 6 different TBE vaccines – two from Western Europe, three from Russia and one from China. The two western European vaccines and one of the Russian vaccines have an adult and a pediatric formulation.
The products names are FSME IMMUN and FSME-IMMUN Junior; Encepur adults and Encepur children, Klesch-E-Vac, EnceVir and EnceVir Neo, Dry lyophilized TBE Moscow and Sen Tai Bao
All TBE vaccines except the one from China have similar but not identical immunization schedules with primary immunization (>3 doses) and regular booster vaccinations. For FSME-IMMUN, Encepur and EnceVir rapid immunization schedules are also licensed. The Chinese vaccine is given with 2 primary doses 2 weeks apart followed by annual boosters.
All vaccines induce significant immune responses. In the absence of a formal correlate of protection, the presence of neutralizing antibodies is used as a surrogate marker for protection.
Recent clinical studies show long-term seropersistence of TBE antibodies after the first booster vaccination (dose 4) with the two European vaccines.
An effectiveness of approximately 99% (years 2000–2006) and 98.7% (years 2000-2011) was calculated for regularly vaccinated persons in Austria, a country with established high vaccination uptake.
Whereas in Western Europe post-exposure prophylaxis with immunoglobulins was discontinued in the late 1990s, in the highly endemic regions of Russia it continues to be common practice.
Both – FSME-IMMUN and Encepur are well tolerated with a well-established safety profile. TBE-Moscow and EnceVir appear to be somewhat more reactogenic.
Chapter 4: Pathogenesis of TBE with a focus on molecular mechanisms
Authors: Kröger Andrea , Överby Anna K.
Published: May 2023

In this chapter we describe the pathogenesis of tick-borne encephalitis virus (TBEV).
To cause infection, TBEV needs to cross three different barriers; the physical, the innate and adaptive and the blood-brain barrier.
The trigger of innate immune and adaptive immune responses, by TBEV is necessary to clear the infection.
TBEV employs strategies to evade the innate immune response.
Tools to study TBEV pathogenicity such as mouse knock-out models and reverse genetics are also discussed.
Chapter 7: TBE in special clinical situations
Authors: Dobler Gerhard , Stoma Igor
Published: May 2023

TBE often takes a severe clinical course in immuno-suppressed patients. In transplant patients TBE usually takes a fatal course. TBE vaccination in immuno-suppressed patients can be non-effective TBE in pregnancy has rarely been reported; from recent cases there is no evidence of transplacental infection of the offspring. The alimentary route of infection of TBE is still common in some European countries resulting in a high clinical manifestation index. TBEV can be infectious in milk and milk products for up to 14 days under optimal environmental conditions. TBE is an important travel-related disease. Increasing numbers of non-endemic countries report imported cases. Imported TBE cases in non-endemic areas pose challenges regarding the diagnosis of TBE.
Total annual and seasonal DM production of improved and unimproved resident pastures at three farms in Canterbury
Authors: Smith Malcolm , Mills Annamaria , Moot Derrick
Published: May 2023

Yield differences between resident and improved pastures were quantified over a 3-4 yr period on three rainfed farms located in North Canterbury (Stockgrove, north of Amberley), Banks Peninsula (Willesden Farm) and the Mid-Canterbury foothills (Inverary Station). Improved pastures produced two- to three-times more feed annually than unimproved resident pastures at each property. At Stockgrove, improved chicory/white clover-based pastures produced 14.1±0.66 t DM/ha/yr compared with 4.36±0.41 t DM/ha/yr from unimproved pastures. Spring accounted for 85% (improved) and 72% (unimproved) of total annual DM production. At Willesden, lucerne monocultures produced 11.5±0.97t DM/ha/yr, which was more than the 4.44±0.45 t DM/ha/yr produced from resident pastures. Improved pastures at Inverary yielded 7.31±0.59 t DM/ha in summer/autumn of 2018/19, which was more than double the 3.34±0.43 t DM/ha from unimproved pastures. In 2019/2020, improved pastures produced 11.7±1.45 t DM/ha compared with 4.45±0.73 t DM/ha. In the third growth season (2020/2021) improved pastures produced 14.1±1.76 t DM/ha compared with 6.67±1.38 t DM/ha from unimproved pastures. In Year 4 (2021/22) the 12.6±1.29 t DM/ha from improved pastures was 56% more than the 8.07±0.85 t DM/ha from the unimproved pastures. Substantial increases in annual and seasonal feed supply patterns can be achieved through hill country pasture improvement.
‘Institutional Psychotherapy Does Not Exist!’
Authors: Apprill Olivier
Published: May 2023

Paying careful attention to the multiple meanings the word ‘institution’ has in French, this article traces the development of institutional psychotherapy’s clinical practice. Through a close reading of Jean Oury’s seminars and clinical writing alongside other key members of the GTPSI (Groupe de travail de psychothérapie et de sociothérapie institutionnelles or Working Group on Institutional Psychotherapy and Socio- therapy), this article argues that institutional psychotherapy’s specificity is in the way in which the clinical and the political are able to connect their praxis.
Collective Militant Analysis
Authors: Caló Susana
Published: May 2023

In Lignes de fuite. Pour un autre monde de possibles, Guattari refers to an ‘analytico-militant programme’ that would position analysis across multiple social fields. What would this correspond to? Through an examination of Guattari’s theorisation of the question of the group in the framework of institutional psychotherapy, this article seeks to open ways to think the general meaning of analysis for social and political purposes and its practical form. The paper will explore what is at stake in the collectivisaton of analysis beyond the group as a social-environmental process and according to a collective machinic perspective of enunciative processes. Analysis will be defined here as an everyday permanent process of creating conditions of autonomy, where self-management is key and alliances are unlocked through a work of analytical metabolism.
Utero-Vesical Fistula Closure after 3 Weeks Treatment with Intravenous Mesenchymal Stem Cells Infusion: Case Report
Authors: Di Silvio Mauricio , Luján-Irastorza Jesús Estuardo , Durand-Montaño Carlos , Henández-Ramos Roberto , Barrón-Vallejo Jesús , Ávila-Rebollar Daniela , Myslabodski Julio , Pariente-Fernández Maruxa , Tagle-Rodríguez Jorge Mario , Ramírez-Amezcua Miguel Ángel , Paredes-Núñez María Angélica , Vargas-Hernández Víctor Manuel
Published: May 2023

Objective: To describe the evolution of Utero-Vesical Fistula (UVF) of one patient who received conservative treatment using intravenous (IV) infusion of 120x106 Adipose tissue Mesenchymal Stem Cells (ADMSCs). Clinical case report: A 36-year-old female presented with postcesarean hematuria 3 hours after an emergency c-section was performed consequently to placental abruption during labor. The primary measure was to use a transurethral Silastic 18F Foley catheter to prevent bladder expansion. The catheter remained for 21 days. Evaluation through Computerized Tomography Cystography (Cysto-CT) revealed failure to close the fistula. The decision to inject ADMSCs as an IV single dose was done. Three weeks after this intervention no blood was seen in the urine drainage bag. Complete resolution of UVF was confirmed with a control CT urogram. Result: Total closure of UVF. Conclusions: The IV infusion of ADMSCs proved to be a plausible and effective conservative treatment of UVF.
A IMPORTÂNCIA DA COMUNICAÇÃO, DA INTELIGÊNCIA EMOCIONAL E DO TRABALHO EM EQUIPE NAS CORPORAÇÕES
Authors:   UEMG - Universidade do Estado de Minas Gerais - Unidade Frutal, CARVALHO Isaar Soares de
Published: May 2023

The article examines the importance of communication, emotional intelligence and teamwork in the corporate world. Justifies the study, the occurrence of several problems in the corporate world, which derive, in short, from misconceptions in communication, both on the part of those who enunciate and those who interpret the statements and orders received. The objective of the work is to examine the importance of dialogue and consensus on what is true and appropriate for corporations, according to the social, economic and political context. As a predicted result, it is expected to delimit part of the scope of a relative and changing truth, especially in the business world. In this context, finally, we will also examine the importance of Emotional Intelligence and Teamwork, seen as fundamental factors for efficiency in the corporate world environment, in the work of Weisinger (1997).
Nem idiomatismo nem técnica estendida: abordagens do vibrafone em Traldi e Rosauro
Authors: Sonsin Isabella Tais , Remuzzi Ficagna Alexandre
Published: May 2023

Muito presentes na literatura acadêmica brasileira sobre vibrafone (e em pesquisas em geral sobre composição, análise ou performance para algum instrumento específico), os conceitos de idiomatismo e técnica estendida são abordados a partir de uma revisão sistemática com ênfase nas problematizações de Padovani e Ferraz (2011), Romão (2012), Labrada (2014) e Hashimoto (2017). A partir desta revisão, propôs-se a perspectiva das “abordagens”, derivadas das duas “filosofias” que Globokar (1992) aponta em relação às práticas percussivas do século XX, com o objetivo de compreender como dois vibrafonistas-compositores, brasileiros e em atividade, compõem para o próprio instrumento em duas peças específicas: Ney Rosauro, em Lied, e Cesar Traldi, em SKYY. Embora não seja um método de análise, esta proposição conceitual permite redirecionar o debate e compreender também como ambos transitam entre diferentes abordagens, de acordo com suas opções estéticas.
Bootstrap confidence for molecular evolutionary estimates from tumor bulk sequencing data
Authors: Huzar Jared , Shenoy Madelyn , Sanderford Maxwell D. , Kumar Sudhir , Miura Sayaka
Published: May 2023

Bulk sequencing is commonly used to characterize the genetic diversity of cancer cell populations in tumors and the evolutionary relationships of cancer clones. However, bulk sequencing produces aggregate information on nucleotide variants and their sample frequencies, necessitating computational methods to predict distinct clone sequences and their frequencies within a sample. Interestingly, no methods are available to measure the statistical confidence in the variants assigned to inferred clones. We introduce a bootstrap resampling approach that combines clone prediction and statistical confidence calculation for every variant assignment. Analysis of computer-simulated datasets showed the bootstrap approach to work well in assessing the reliability of predicted clones as well downstream inferences using the predicted clones (e.g., mapping metastatic migration paths). We found that only a fraction of inferences have good bootstrap support, which means that many inferences are tentative for real data. Using the bootstrap approach, we analyzed empirical datasets from metastatic cancers and placed bootstrap confidence on the estimated number of mutations involved in cell migration events. We found that the numbers of driver mutations involved in metastatic cell migration events sourced from primary tumors are similar to those where metastatic tumors are the source of new metastases. So, mutations with driver potential seem to keep arising during metastasis. The bootstrap approach developed in this study is implemented in software available athttps://github.com/SayakaMiura/CloneFinderPlus.
Titanium surface interacting with blood clot enhanced migration and osteogenic differentiation of bone marrow mesenchymal stem cells
Authors: Li Jia , Zhao Juan , Xu Yangbo , Xu Antian , He Fuming
Published: May 2023

Introduction: Blood clot formation is the initial phase upon implantation, and the feature of blood clot orchestrates the following complement system activation, coagulation cascade, and bone marrow mesenchymal stromal cells (BMSCs) recruitment. This study aimed to investigate the effect of implant surface on blood-material interactions and subsequent BMSC cellular behaviors.

Methods: This study was established to imitate the physiological process of implantation in vivo and in vitro. Whole blood was incubated with polished titanium (PT) surfaces and sandblasted and double acid-etching (SLA) surfaces for 10 min or 2 h, then seeded with BMSCs. The adhesion, proliferation, migration, and differentiation of cells were studied at specific time points. Titanium implants were implanted into the tibia in vivo and were screwed out after implantation. The activation of the coagulation cascade, platelets, complement system, and clot networks were assessed and further quantitatively analyzed.

Results: Compared with the PT surface, the SLA surface induced the earlier and stronger blood coagulation cascade and formed a more stratified clots network with fibrinogen, platelets, and CD14 positive cell. The adhesion, proliferation, and migration of BMSCs were enhanced by pre-incubated surfaces. The higher levels of the osteogenic-related genes, ALP activity, and calcium nodule formation were showed on SLA surfaces with blood incubation.

Conclusion: SLA titanium surfaces play a role in influencing the formation of blood clots and coordinating surface-blood interactions and cell biological processes. These findings provide the idea of modifying the blood clots formed on the implant surface by biomaterials modification and thus has implications for the development of better osteogenic biomaterials.
Efficient adeno-associated virus serotype 5 capture with affinity functionalized nanofiber adsorbents
Authors: Neto Salomé , Mendes João P. , Santos Susana B. Dos , Solbrand Anita , Carrondo Manuel J. T. , Peixoto Cristina , Silva Ricardo J. S.
Published: May 2023

Adeno-associated viruses (AAVs) are one of the most promising tools for gene therapy applications. These vectors are purified using affinity and ion exchange chromatography, typically using packed beds of resin adsorbents. This leads to diffusion and pressure drop limitations that affect process productivity. Due to their high surface area and porosity, electrospun nanofiber adsorbents offer mass transfer and flow rate advantages over conventional chromatographic media. The present work investigated the use of affinity cellulose-based nanofiber adsorbents for adeno-associated virus serotype 5 (AAV5) capture, evaluating dynamic binding capacity, pressure drop, and AAV5 recovery at residence times (RT) less than 5 s. The dynamic binding capacity was found to be residence time-dependent, but nevertheless higher than 1.0 × 1014 TP mL−1 (RT = 1.6 s), with a pressure drop variation of 0.14 MPa obtained after loading more than 2,000 column volumes of clarified AAV5 feedstock. The single affinity chromatography purification step using these new affinity adsorbents resulted in 80% virus recovery, with the removal of impurities comparable to that of bead-based affinity adsorbents. The high binding capacity, virus recovery and reduced pressure drop observed at residence times in the sub-minute range can potentially eliminate the need for prior concentration steps, thereby reducing the overall number of unit operations, process time and costs.
Functional hydrogels for the repair and regeneration of tissue defects
Authors: Li Xinlin , Xu Mengfei , Geng Zhaoli , Liu Yi
Published: May 2023

Tissue defects can be accompanied by functional impairments that affect the health and quality of life of patients. Hydrogels are three-dimensional (3D) hydrophilic polymer networks that can be used as bionic functional tissues to fill or repair damaged tissue as a promising therapeutic strategy in the field of tissue engineering and regenerative medicine. This paper summarises and discusses four outstanding advantages of hydrogels and their applications and advances in the repair and regeneration of tissue defects. First, hydrogels have physicochemical properties similar to the extracellular matrix of natural tissues, providing a good microenvironment for cell proliferation, migration and differentiation. Second, hydrogels have excellent shape adaptation and tissue adhesion properties, allowing them to be applied to a wide range of irregularly shaped tissue defects and to adhere well to the defect for sustained and efficient repair function. Third, the hydrogel is an intelligent delivery system capable of releasing therapeutic agents on demand. Hydrogels are capable of delivering therapeutic reagents and releasing therapeutic substances with temporal and spatial precision depending on the site and state of the defect. Fourth, hydrogels are self-healing and can maintain their integrity when damaged. We then describe the application and research progress of functional hydrogels in the repair and regeneration of defects in bone, cartilage, skin, muscle and nerve tissues. Finally, we discuss the challenges faced by hydrogels in the field of tissue regeneration and provide an outlook on their future trends.