bluuebunny/crossref_metadata_2025 huggingface dataset:
Serotonin adipate in intensive therapy of patients with severe COVID-19
Authors:   Clinical Hospital for Infectious Diseases No 2, Moscow, Russian Federation, Bykov M.V. ,   Central Research Institute of Epidemiology of the Federal Service on Customers' Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation, Chernyshyov D.V. ,   Clinical Hospital for Infectious Diseases No 2, Moscow, Russian Federation, Lazareva E.N. ,   Clinical Hospital for Infectious Diseases No 2, Moscow, Russian Federation,   Central Research Institute of Epidemiology of the Federal Service on Customers' Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation, Krasnova S.V. ,   Clinical Hospital for Infectious Diseases No 2, Moscow, Russian Federation, Tsvetkova N.A. ,   Clinical Hospital for Infectious Diseases No 2, Moscow, Russian Federation, Ponezheva Zh.B. ,   Central Research Institute of Epidemiology of the Federal Service on Customers' Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation, Akimkin V.G. ,   Central Research Institute of Epidemiology of the Federal Service on Customers' Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation, Maleev V.V. ,   Central Research Institute of Epidemiology of the Federal Service on Customers' Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation
Published: April 2022

In this article, we discuss the history of discovery of serotonin deficiency and therapy for it. We described the experience of using serotonin adipate as a part of comprehensive intensive therapy for severe COVID-19. We also describe treatment outcome of a 52-year-old female patient treated in the intensive care unit of the Clinical Hospital for Infectious Diseases No 2 with a diagnosis of community-acquired polysegmental pneumonia, confirmed COVID-19, and functional intestinal obstruction. Her condition was complicated by infectious and toxic dilated cardiomyopathy of mixed origin (caused by both coronavirus itself and substrates of enterogenic endotoxicosis) and hemodynamic instability manifesting itself with arterial hypotension that required micro-injections of norepinephrine. The comprehensive treatment aimed to eliminate growing endotoxicosis caused by intestinal insufficiency, so we had to adjust her intensive therapy by adding serotonin adipate to the treatment scheme. Good treatment outcome of this patient was ensured by an improved strategy of intensive therapy that included a drug restoring and stimulating functions of smooth muscles. Later, the patient was transferred to the specialized department, recovered, and discharged from hospital. Key words: intensive care, COVID-19, serotonin adipate
Characteristics of patients with severe and extremely severe SARS-CoV-2 infection treated in the intensive care unit of Nalchik Hospital No 1
Authors:   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation, Marzhokhova A.R. , Ploskireva A.A. ,   Central Research Institute of Epidemiology of The Federal Service on Customers' Rights Protection and Human Well-being Surveillance, Moscow, Russian Federation, Kharaeva Z.F. ,   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation, Marzhokhova M.Yu. ,   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation, Balagova L.E. ,   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation, Ivanova M.R. ,   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation, Shomakhova Z.A. ,   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation, Pazova Zh.Yu. ,   Kh.M.Berbekov Kabardino-Balkar State University, Nalchik, Russian Federation
Published: April 2022

The first patients with SARS-CoV-2 infection were registered in Kabardino-Balkar Republic (KBR) in the end of March 2020, when Hospital No 1 at the Center for AIDS and Infectious Diseases was completely equipped for the admission of COVID-19 patients. Objective. To assess clinical and laboratory characteristics of patients with severe and extremely severe COVID-19 treated in the intensive care unit of Hospital No 1 in Nalchik in 2020–2021. Patients and methods. A total of 283 patients were treated in the intensive care unit (ICU) during this year. More that one-third of patients (41.3%) died; most of them were male. The majority of patients in the ICU were between 61 and 70 years of age; the majority of deaths were registered among patients aged 71 to 80 years. One hundred and seventy-three individuals in the ICU required non-invasive or invasive ventilation; 105 of them (60.7%) died. Two hundred and fifty-two patients (89%) had severe concomitant diseases. The disease severity was also determined by advanced lung damage (more than 50%) in 143 patients (50.5%). Patients were examined and treated in accordance with temporary guidelines (effective at that time). Results. The most common causes of death among patients treated for COVID-9 in the ICU were pulmonary embolism (n = 50; 42.75%), sepsis (n = 19; 16.2%), and acute respiratory failure (n = 17; 14.5%). Key words: coronavirus infection, SARS-CoV-2, intensive care unit
Antibiotic resistance of Moraxella catarrhalis strains isolated from patients with complicated acute respiratory viral infections and other acute respiratory diseases
Authors:   Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, Saint Petersburg, Russian Federation, Kraeva L.A. ,   S.M.Kirov Military Medical Academy, Saint Petersburg, Russian Federation, Burgasova O.A. ,   Peoples' Friendship University of Russia (RUDN), Moscow, Russian Federation,   N.F.Gamaleya National Research Center for Epidemiology and Microbiology, Moscow, Russian Federation, Petrova I.S. ,   Clinical Hospital for Infectious Diseases No 2, Moscow, Russian Federation, Samoylova A.A. ,   Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, Saint Petersburg, Russian Federation, Rogacheva E.V. ,   Saint Petersburg Pasteur Research Institute of Epidemiology and Microbiology, Saint Petersburg, Russian Federation, Taranova M.V. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Bespalova G.I. ,   I.I.Mechnikov North-Western State Medical University, Saint Petersburg, Russian Federation
Published: April 2022

In recent years, acute respiratory viral infections (ARVIs) and other acute respiratory diseases (ARDs) have acquired some new characteristics of the disease course. The structure of complications has changed, in particular, such complications as community-acquired pneumonia (CAP) and lesions to the upper respiratory tract have become significantly more common. CAP remains one of the main causes of death in patients with ARVIs and other acute respiratory infections due to bacterial resistance to antibiotics. Objective. To assess drug sensitivity of Moraxella catarrhalis strains isolated from patients with complicated ARVIs or ARDs. Materials and methods. Drug susceptibility assessment was performed using the disk diffusion method (DDM) and gradient diffusion method (E-test). The production of β-lactamases was evaluated using nitrocephine, a chromogenic substrate. Results. Isolated strains of M. catarrhalis were resistant to third-generation cephalosporins and sensitive to fourth- and fifthgeneration cephalosporins. More than 70% of M. catarrhalis strains developed resistance to macrolides; 8% of strains were resistant to amoxiclav. All isolated M. catarrhalis strains were sensitive to respiratory fluoroquinolones, carbapenems, and ampicillin-sulbactam. Key words: Moraxella catarrhalis, complications of acute viral infections, bacterial sensitivity to antibiotics
Persistent hiccups as a new chief complaint of patients with COVID-19: A series of four cases
Authors:   Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran, Shahramian Iraj , Mirzaie Hadi ,   Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran, Salarzaei Morteza ,   Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran, Parooie Fateme ,   Pediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran
Published: April 2022

A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019, and it was known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Committee on Taxonomy of Viruses (ICTV). we encountered four patients whose only symptom was hiccups, and they were found to be COVID-19 positive with real-time polymerase chain reaction (RT-PCR). Case presentation. Four cases with 45,57,38 and 19 years of age presented with persistent hiccups as the main and only symptom of their disease. All patients were stable and received only symptomatic treatment and were discharged after 14 days that the second swab result came as negative. Discussion and conclusion. In the present study, the researchers have identified 4 cases that had a new, and perhaps rare, symptom - here hiccups - and investigated these cases meticulously and also separately. This report addresses two remarkable factors: firstly, it indicates the importance of the exact examination of those presenting with hiccups, at least by taking a detailed history of patients, a comprehensive physical examination, obtaining basic laboratory work, and also taking a chest X-ray. Secondly, physicians need to prepare for facing the new symptoms of Covid-19 disease. Key words: Hiccup, Covid-19, corona virus
Clinical and laboratory characteristics COVID-19
Authors:   Dagestan State Medical University, Makhachkala, Russian Federation, Shikhnebiev D.A. , Ragimov R.M. ,   Dagestan State Medical University, Makhachkala, Russian Federation, Tagirova Z.G. ,   Dagestan State Medical University, Makhachkala, Russian Federation,   S.M.Magomedov Republican Center for Infectious Diseases, Prevention and Control of AIDS, Makhachkala, Russian Federation, Abdullaeva N.M. ,   Dagestan State Medical University, Makhachkala, Russian Federation, Muslimova A.E. ,   Dagestan State Medical University, Makhachkala, Russian Federation
Published: April 2022

The problem of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) remains highly relevant. Objective. To analyze clinical and laboratory characteristics of patients with moderate COVID-19. Materials and methods. This retrospective study included 132 patients with moderate COVID-19 treated in the Republican Immunological Center of the Republic of Dagestan between July and December 2020. The sample included 69 males and 63 females with a mean age of 52.4 ± 5.9 years. Results. The most common clinical manifestations included fever, fatigue, dry cough, and headache. Many participants had increased erythrocyte sedimentation rate (ESR); some patients had leukopenia, lymphopenia, and thrombocytopenia. Biochemical testing demonstrated mild alterations in the levels of C-reactive protein (CRP), ferritin, glucose, activity of liver enzymes (alanine aminotransferase, as-partate aminotransferase), fibrinogen, and D-dimer. These alterations were primarily observed in COVID-19 patients with CT-2 changes in their lung tissue. One-third of participant had lesions in lungs upon discharge. ECG changes (rhythm and conduction abnormalities) were detected in 15.9% of patients with concomitant cardiovascular diseases. Conclusion. COVID-19 patients with persistent clinical, laboratory, or radiological changes upon their discharge from hospital, as well patients with changes on ECG, require careful follow-up to assess their long-term outcomes. Key words: COVID-19, SARS-CoV-2, coronavirus, clinical and laboratory parameters, coagulogram, ECG changes, radiological changes
The medical and social significance of schistosomiasis at the present stage. Schistosomiasis in the Republic of Guinea
Authors:   People’s Friendship University of Russia (RUDN), Moscow, Russian Federation, Kamara G. , Burgasova O.A. ,   People’s Friendship University of Russia (RUDN), Moscow, Russian Federation,   N.F.Gamaleya Federal Research Centre of Epidemiology and Microbiology, Moscow, Russian Federation, Tokmalaev A.K. ,   People’s Friendship University of Russia (RUDN), Moscow, Russian Federation
Published: April 2022

Schistosomiasis are registered in more than 70 countries of the world in which more than 250 million people are infected, about 800 million people are at high risk of infection, and the number of deaths associated with the disease reaches 200,000 people per year. The African region accounts for about 90% of all cases. Due to the low results of many years of struggle in many endemic foci, schistosomiasis gradually passed into the category of "neglected tropical diseases". However, according to the modern WHO roadmap, the fight against schistosomiasis has again become one of the priorities, which is directly related to new diagnostic capabilities. Due to the low sensitivity of traditional microscopy, the often long asymptomatic course of the disease, the absence of pathognomonic symptoms and the high risk of developing severe complications (malignant neoplasms, liver cirrhosis, secondary infertility, increased risk of HIV infection), there is an urgent need for a new "gold standard" of diagnostics, based on modern immuno-serological and molecular genetic methods, which would meet the ASSURED criteria (Affordable, Sensitive, Specific, User friendly, Rapid and robust, Equipment free and Deliverable). Increasing the diagnostic capabilities of medical centers in endemic zones, especially in the Republic of Guinea, and extensive population studies using sensitive methods will allow timely detection of schistosomiasis among the population especially in children, who are the most vulnerable contingent, and obtain reliable statistical data, which will become the basis for optimizing the strategy fight against dangerous helminthiasis. Praziquantel remains the treatment of choice for all types of schistosomiasis. Key words: optimization of control strategy, new "gold standard" of diagnostics, immuno-serological, molecular-genetic methods
Clinical and immunological characteristics of COVID-19 associated with human herpesvirus infections: management algorithms for mixed infections
Authors:   Research Information Center for the Prevention and Treatment of Viral Infections, Moscow, Russian Federation, Vikulov G.Kh. ,   Herpetic Center Gamidov Clinic, Moscow, Russian Federation, Oradovskaya I.V. ,   Institute of Immunology, Federal Biomedical Agency, Moscow, Russian Federation
Published: April 2022

This article discusses important aspects of human herpesvirus reactivation associated with COVID-19 and secondary immunodeficiency. It also presents the overall diagnostic and treatment algorithm for patients with mixed infections. Key words: SARS-CoV-2, COVID-19, human herpesviruses, epidemiology, algorithm
Real-Time Light-Guided Vocal Fold Injection via the Cricothyroid Membrane in Unilateral Vocal Fold Paralysis: A Human Pilot Study
Authors: Huh Gene , Jang Pil Geun , Han Seung Hoon , Mohammad Ramla Talib , Jeong Woo Jin , Cha Wonjae
Published: April 2022

Objectives. Vocal fold injection (VFI) via the cricothyroid (CT) membrane is used to treat various diseases affecting the vocal folds. The technical challenges of this technique are mainly related to the invisibility of the needle. Real-time light-guided VFI (RL-VFI) was recently developed for injection under simultaneous light guidance in the CT approach. Herein, we present the first clinical trial of RL-VFI, in which we investigated the feasibility and safety of this new technique in unilateral vocal fold paralysis (VFP).Methods. This prospective pilot study enrolled 40 patients, who were treated with RL-VFI for unilateral VFP between September 2020 and August 2021. Adverse events were monitored during the procedure and for 4 weeks postoperatively. The Voice Handicap Index-10, the GRBAS (grade, roughness, breathiness, asthenia, and strain) scale, aerodynamic studies, and acoustic analyses were evaluated to compare the voice improvement after 4 weeks with the baseline values.Results. The needle tip was intuitively identified by the red light. The mean procedure time was 95.6±40.6 seconds for the initial injection, while the additional injection required 79.2±70.5 seconds. The injection was performed under light guidance without additional manipulation after the needle reached the intended point. No acute or delayed adverse events were reported. Among the 40 patients, 36 completed voice analyses after 4 weeks. Subjective and objective voice parameters, including the Voice Handicap Index-10, GRBAS scale, maximum phonation time, mean expiratory airflow, fundamental frequency, jitter, shimmer, and noise-to-harmonics ratio improved significantly after RL-VFI (P<0.05), while the expiratory volume was maintained.Conclusion. RL-VFI is feasible and safe for treating patients with unilateral VFP. This technique is anticipated to improve the precision and safety of the CT approach in the treatment of unilateral VFP. This study provides a rationale for further structured clinical studies.
Hyaluronan Synthase 1: A Novel Candidate Gene Associated With Late-Onset Non-syndromic Hereditary Hearing Loss
Authors: Umugire Alphonse , Lee Sungsu , Lee Chang-Joon , Choi Youngmi , Kim Taekyoung , Cho Hyong-Ho
Published: April 2022

Objectives. Hyaluronan synthase 1 (HAS1) is a membrane-bound protein that is abundant in the epidermis and dermis, and it is important for skin function. However, its association with hearing loss has not yet been studied. Herein, we sought to evaluate the potential contribution of HAS1: c.1082G>A to genetic hearing loss.Methods. We used whole-exome sequencing to analyze blood DNA samples of six patients of a family with autosomal dominant familial late-onset progressive hearing loss, which was revealed to be related to a variant of the HAS1 gene. Confirmatory Sanger sequencing was performed with samples from 10 members. A missense variant was detected in HAS1 (c.1082 G>A, p.Cys361Tyr). In silico analyses predicted this variant to result in the functional loss of HAS1. Immunostaining was conducted using wild-type mouse samples to verify HAS1 expression.Results. Has1 was detected in an otocyst at E10.5. In the pup, Has1 expression was localized in the stria vascularis (SV), hair cells, supporting cells of the organ of Corti, and some spiral ganglion neurons. SV marginal cells markedly expressed Has1 in the adult stage. The hearing threshold in the Has1-depleted condition was investigated by accessing the International Mouse Phenotyping Consortium’s Auditory Brainstem Response (ABR) data. ABR of Has1 knock-out mice showed threshold elevations at 6, 12, and 18 kHz in young male adults.Conclusion. HAS1 may have a close relationship with auditory function and genetic hearing loss. Further investigation is needed to reveal the precise role of HAS1 in the auditory system. HAS1 is a candidate gene for future hereditary hearing loss genetic testing.
Clinical and Laboratory Features of Various Criteria of Eosinophilic Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis
Authors: Kim Do Hyun , Kim Sung Won , Basurrah Mohammed Abdullah , Hwang Se Hwan
Published: April 2022

Objectives. The aim of this study was to evaluate the differences in clinical and laboratory features between eosinophilic chronic rhinosinusitis (ECRS) and non-ECRS and to compare diagnostic criteria for ECRS.Methods. We compared clinical features and/or laboratory findings classified as ECRS and non-ECRS according to various diagnostic criteria (histological and clinical). We also analyzed studies to compare endoscopic findings, symptom scores, laboratory findings, and computed tomography (CT) findings between ECRS and non-ECRS.Results. Our search included 55 studies with 6,143 patients. A comparison of clinical features and/or laboratory criteria with histological criteria showed no significant differences in nasal symptom scores and CT scores according to criteria. Serum eosinophil levels showed differences across the criteria, with ECRS consistently characterized by higher serum eosinophil levels than non-ECRS. Among the four criteria, the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) criteria and tissue eosinophilia (≥70) were associated with decreased olfactory function. In laboratory findings, the eosinophil percentage (standardized mean difference [SMD], 1.561; 95% confidence interval [CI], 1.329–1.794; P<0.001) and eosinophil count (SMD, 1.493; 95% CI, 1.134–1.852; P<0.001) of eosinophils were higher in ECRS than non-ECRS. In clinical findings, nasal symptom scores (SMD, 0.382; 95% CI, 0.156–0.608; P<0.001), endoscopic nasal polyp scores (SMD, 0.581; 95% CI, 0.314–0.848; P<0.001), and olfactory dysfunction (SMD, 0.416; 95% CI, 0.037–0.794; P=0.031) were higher in ECRS than in non-ECRS. With regard to CT findings, the whole-sinus opacification score (SMD, 0.824; 95% CI, 0.588–1.059; P<0.001) was higher in ECRS than in non-ECRS. In particular, there were significant differences in anterior ethmoid sinus and sphenoid sinus opacification.Conclusion. ECRS and non-ECRS differ in their clinical and laboratory features. When histological confirmation is difficult on an outpatient basis, ECRS could be diagnosed using clinical features and/or laboratory findings.
Simplification of Lesson Plan: Elementary School Teacher Perspective
Authors: Vicky Dwi Wicaksono
Published: April 2022

The policy of simplifying lesson plans as part of the Free Learning Program by the Ministry of Education and Culture has a direct impact on elementary school teachers as drafters of lesson plans. This study aims to find out how teachers view the simplification of the Lesson Plan (RPP) in elementary schools. By using the method of questionnaires and interviews from the point of view of elementary school teachers, it can be found the effectiveness, constraints, and strategies in implementing the new format of lesson plans in elementary schools. The results of the study indicate that the new format of lesson plans can reduce the burden of teacher administrative tasks so that classroom learning becomes more qualified. Elementary school teachers in simplifying thematic lesson plans have their own challenges, combining several subjects into a series of teaching and learning activities into a very simple lesson plan. The strategies that have been carried out by schools to implement this policy are KKG training; peer tutors; and internet sources.
Changes made to the teaching of linear algebra and calculus courses in the UK in response to the COVID-19 pandemic
Authors: Alarfaj Maryam , O'Hagan Steven , Sangwin Chris
Published: April 2022

In response to the COVID-19 pandemic, university mathematics departments in the UK adapted their teaching for 2020-21, with some courses being delivered digitally and others through a mixture of on-campus and digital delivery. A survey of linear algebra and calculus lecturers was carried out in the spring of 2021 to investigate what changes were made to courses, as well as lecturers’ perceptions of institutional decision making and support. This survey found that a majority of the 41 participants were satisfied that the choice of delivery mode was correct, although views about the importance of offering on-campus classes were mixed. There was a significant increase in the use of video clips made by the lecturer, video-conferencing software, discussion forums, electronic submission of written work and on-screen marking tools. Most lecturers reported a reduction in the amount of time that students were expected to be taking part in live teaching activities and an increase in the amount of time they were expected to be working on asynchronous activities. While some were keen to return to their previous practice, others were enthusiastic about retaining features introduced in response to the COVID-19 pandemic.
The impact of remote teaching on statistics learning and anxiety
Authors: Marshall Ellen May , Mahmood Bilal , Alexander Craig , Bock Mitchum , Haigney Diane , Jack Eilidh , Verrier Diarmuid
Published: April 2022

In March 2020, staff and students at UK universities had to suddenly transition from on-campus teaching to remote learning as a result of the pandemic, which continued throughout the 2020/21 academic year. Unlike traditional online learners, students may lack the motivation or confidence to learn as effectively online particularly for modules such as statistics which students often find difficult or stressful face to face.This paper uses survey results from students studying elective and compulsory statistics modules in the 2020/21 academic year to gain an insight into remote learning of statistics from the students’ perspective.When compared to previous face to face teaching of statistics, students were less likely to actively engage with material, ask for help or work with peers remotely. Emotional wellbeing, motivation to learn, statistics anxiety and having a suitable learning environment all impacted on being able to learn statistics remotely. Although statistics anxiety in online teaching situations was generally lower, there was no evidence to suggest anxious students would benefit from online learning going forward.
O Programa Cisternas nas Escolas nos Vales do Jequitinhonha e do Mucuri, Minas Gerais, Brasil
Authors: Vieira Naldeir dos Santos , Lopes Daniel Paulino Teixeira , Honorato da Silva Fernanda Aparecida Guedes , Soares Nathalia Stockler Fialho , Higuchi Agnaldo Keiti
Published: April 2022

- Objetivo da pesquisa: O presente artigo tem como objetivo analisar os resultados do Programa Cisternas nas Escolas, na perspectiva de servidores de escolas localizadas nos vales do Jequitinhonha e do Mucuri, estado de Minas Gerais.
- Enquadramento teórico: O artigo é fundamentado em autores que descrevem as principais características da região semiárida brasileira, com destaque para Dias (2013), Souza et al. (2016) e Sousa et al. (2017) e do Programa Cisternas nas Escolas, com destaque para Gottfried (2010), Costa e Dias (2013), Santana e Arsky (2016), Detrich (2019), ASA (2020) e Santos e Borja (2020).
- Metodologia: Por meio de material fornecido pelo Ministério da Cidadania e pela Articulação no Semiárido Brasileiro (ASA), foram mapeadas as escolas dos municípios do campo estudado que construíram cisternas via o Programa. Foi identificado o universo de 132 escolas, analisadas estatisticamente por meio de questionários respondidos por um de seus representantes (taxa de retorno de 75%).
- Resultados: Verificou-se que o Programa cumpre o seu objetivo, sendo, de modo geral, bem avaliado pelos representantes das escolas beneficiadas, que em sua maioria se mostraram satisfeitos com a cisterna, com o seu estado de conservação, com as orientações recebidas e com o impacto desta tecnologia na vida dos alunos.
- Originalidade: Por mais que a literatura permita a identificação de um número razoável de estudos sobre o Programa Cisternas, são raros os estudos sobre o Programa Cisternas nas Escolas.
- Contribuições: Os dados da pesquisa chamam atenção para algumas questões que devem ser pontuadas para o aperfeiçoamento do Programa. Além disso, foi identificada a necessidade de medidas para o aperfeiçoamento do manuseio da cisterna e da água por ela armazenada.
Early Neoproterozoic Tectonics in the Godhra–Chhota Udepur Sector: Evidence for Two-Stage Accretion in the Great Indian Proterozoic Fold Belt
Authors: Banerjee Anwesa , Sequeira Nicole , Cogné Nathan , Prabhakar N. , Bhattacharya Abhijit
Published: April 2022

The Great Indian Proterozoic Fold Belt (GIPFOB) is a curviplanar highly-tectonized zone of Precambrian crystalline rocks. In the GIPFOB, the N/NNE-striking western arm (the Aravalli Delhi Fold Belt, ADFB) and the E-striking southern arm consisting of the Chottanagpur Gneiss Complex (CGC) and the central/southern domains of the Satpura Mobile Belt (SMB) converge at the Godhra-Chhota Udepur sector. To investigate the tectonics of the sector, we combine the results of analyses of mesoscale and regional structures, U-Pb (zircon) geochronology, and monazite chemical dating to constrain the convergence. The sector is dominated by an ensemble of shallow-dipping granitoid mylonites (D2 deformation) and recumbently folded anatectic granulite-facies basement gneisses interleaved with allochthonous greenschist/epidote-amphibolite facies supracrustal rocks thrust top-to-the-south. The shallow-dipping carapace is traversed by a network of E-striking steep-dipping shear zones with sinistral and N-down kinematics (D3 deformation). The D3 shear zone hosted granitoids exhibit E-striking suprasolidus deformation fabrics and chessboard microstructures. In the shallow-dipping carapace, the partly overlapping stretching lineations associated with D2-D3 deformations share low-angle obliquities with the W/WNW plunging hinges of D2 recumbent folds and the upright/moderately-inclined D3 folds in the basement gneisses and the supracrustal rocks. The transition from thrust-dominated (D2) to wrench-dominated (D3) deformation involved flipping of Y and Z strain axes for similar orientations of orogen-parallel stretching caused by N-S shortening. U-Pb LA-ICP-MS (zircon) and monazite chemical dates suggest the D2-D3 deformation and felsic plutonism occurred at 0.95–0.90 Ga, the pre-D2 high-grade metamorphism in the anatectic gneisses at 1.7–1.6 Ga. The 0.95–0.90 Ga structures in the Godhra-Chhota Udepur are identical to those in CGC-SMB in the southern arm and terminate the N/NNE-striking structures in the ADFB. We suggest the GIPFOB comprises two Early Neoproterozoic accretion zones, e.g., the western arm (ADFB) and the younger (GC-SMB-CGC) southern arm.
Los hábitos de salud y la adaptación a la pandemia de covid en méxico
Authors: Álvarez Bermúdez Javier , Meza Peña Cecilia , NODO MÉXICO GRUPO PSYCOVID
Published: April 2022

Objetivo. Conocer los efectos de la pandemia en los hábitos alimentarios, sueño y actividad física y su influencia en la adaptación a la misma. Método. Es un estudio es transversal, correlacional, comparativo y predictivo, con muestra intencional de 7,439 personas, 69.9% mujeres y 30.1% hombres, con una media de edad de 36.9. Se empleó un instrumento (α=.81), que mide hábitos de salud, alimentación, ejercicio y sueño (α=.61), así como de adaptación al confinamiento (α=.65). Resultados. El 52% de los participantes disminuyeron su actividad física, las dificultades de sueño fueron reportadas por un 58%, el 29.3% cambios negativos en su alimentación y el 8.6% reportó dificultades en adaptación al confinamiento. El hábito que mejor predice la adaptación a la pandemia fue el sueño, seguido de cambios alimentarios y finalmente actividad física. Conclusiones. Es importante mantener los hábitos saludables como factores protectores  y por su influencia en la adaptación a la pandemia.
Self-reported executive function mediates the association between obesity and recent suicidality
Authors: Toledo Fernández Aldebarán , Baca Hernández Diego , Guerrero Hernández Mariana , Moreno Barbosa Osvaldo , Villalobos Gallegos Luis
Published: April 2022

Abstract

The study intended to test for mediation effects of self-reported executive function (EF) between obesity and past 30-days suicide-behaviors. A web-based survey was conducted diffusing it to the general Mexican population via social media. Suicide was evaluated with the corresponding module of the Mini International Neuropsychiatric Interview, and a short form of the Behavioral Rating Inventory of Executive Functions-Adults for EF. Body mass index was computed from the self-reported height/weight. Causal-mediation analyses was performed for each of the suicide variables, including obesity and EF as predictor and mediator, respectively. Data from 1234 participants was analyzed, 274 classified as having obesity. EF partially mediated 20% of the effect of obesity on suicide behaviors. As the BMI progresses to the categories of obesity, EF deficiencies may be insufficient to cope optimally with the emotional and social stressors associated to obesity, thus leading to more frequent or intense suicide ideation, planning or attempts.
Ansiedad y Depresión en Pacientes con Trastornos Gastrointestinales Funcionales de Argentina
Authors: Ortega Ivana Soledad , Donatti Sofía , Cremades Camila , Garay Cristian Javier
Published: April 2022

Los trastornos gastrointestinales funcionales (TGF) se caracterizan por la ausencia de anormalidades anatómicas o fisiológicas, y por presentar un curso crónico y recurrente. Su prevalencia mundial es del 40% aproximadamente. Los factores psicológicos ocupan un lugar importante en el desarrollo y mantenimiento de los TGF. Si bien se ha estudiado la relación entre los TGF con la ansiedad y la depresión, no se cuenta con datos a nivel local. El objetivo del presente estudio fue conocer los niveles de ansiedad y depresión en pacientes con diagnóstico de TGF en una muestra local. Se estudiaron 46 pacientes diagnosticados con un TGF. Se utilizó el Inventario de Depresión de Beck II (BDI II) para evaluar el nivel de depresión, y el Inventario de Ansiedad Estado-Rasgo (STAI) para evaluar el nivel de ansiedad. El 17.78% presentó depresión leve, el 26.67% depresión moderada y el 22.22% depresión severa. El 33.33% no presentó depresión. La mediana reportada en ansiedad estado fue 87 (IQR = 23.75) y la de ansiedad rasgo fue 93 (IQR = 16).  Se encontró asociaciones directas significativas entre depresión y ansiedad estado (r(44) = .54, p<.001) y entre depresión y ansiedad rasgo (r(44) = .61, p<.001). Los resultados reflejan que las personas con un TGF presentan altos niveles de ansiedad y depresión, similar a lo encontrado en otros estudios. Conocer estos datos permitirá mejorar los tratamientos para esta población, enfocados desde un abordaje interdisciplinario.
Apego, duelo y continuidad de lazos en el afrontamiento de la pérdida
Authors: Fernández Pérez Estela , Garces de Los Fayos Ruiz Enrique Javier , Peinado Portero Ana Isabel
Published: April 2022

Esta revisión sistemática ha considerado la literatura publicada en los últimos 30 años sobre las relaciones existentes entre el apego, el proceso de duelo y el afrontamiento de la pérdida. El apego es el vínculo que se establece en el momento del nacimiento, principalmente con los cuidadores primarios. El proceso de duelo es la reacción que se produce ante la pérdida de una relación cercana. La continuidad de lazos es una herramienta que utilizan los dolientes para mantenerse unidos al fallecido.  El trabajo se fundamenta principalmente en estudios empíricos con muestras de sujetos donde, en su mayoría, se tomaban medidas de apego, de duelo y de continuidad de lazos. Los resultados de dichos estudios arrojan relaciones entre las tres variables, sin embargo, no se pueden establecer relaciones causales, por lo que se necesita más investigación que pueda esclarecer la relación existente entre dichas variables. En términos generales, el apego seguro se relaciona con un proceso de duelo más adaptativo y el apego ansioso y evitativo dificultan el proceso de duelo. Por otro lado, la continuidad de lazos con el fallecido resultará adaptativa o desadaptativa en función de si se ajustan o no al sistema de significado dominante de la persona.
Resiliencia y lesiones en deportistas universitarios
Authors: Moo Peña Juan Carlos , Solís Briceño Omar B
Published: April 2022

Introducción. La lesión deportiva se relaciona con muchos factores psicológicos siendo uno de ellos la resiliencia, factor que se relaciona con la autoestima, enfrentamiento y apoyo social. Objetivo. Identificar las variables de resiliencia, autoestima, enfrentamiento y apoyo social en una población de deportistas universitarios y comprobar si existe relación entre dichas variables y las lesiones deportivas con base en la presencia o ausencia de lesión. Método. Se presentan datos descriptivos de 137 deportistas universitarios y un análisis de correlación de la variable lesión deportiva con las variables resiliencia, autoestima, enfrentamiento y apoyo social. Resultados. Se obtuvieron puntuaciones altas en todas las variables y se encontraron correlaciones casi afines entre la resiliencia de los deportistas lesionados y no lesionados con las variables predictores de la resiliencia. Conclusión. Los deportistas universitarios tienen una tendencia a presentar niveles altos de resiliencia haya o no la presencia de una lesión deportiva.
Variables biopsicosociales que discriminan el tipo de tratamiento farmacológico en diabetes
Authors: Rondón Bernard José Eduardo
Published: April 2022

Marco teórico: El tratamiento farmacológico de la diabetes mellitus tipo 2 consiste en el uso de antidiabeticos orales y/o insulina, lo anterior dependerá de las características del paciente y del estadio evolutivo de la condición. Derivado de lo anterior, se pretendió determinar si el tiempo de evolución de la condición, el sexo, el nivel de instrucción, el locus de control en salud y las estrategias de afrontamiento discriminan a las personas con diabetes mellitus tipo 2 que emplean insulina de aquellas que usan antidiabéticos orales. Método: Se aplicó el Cuestionario de Estrategias de Afrontamiento y la Escala Multidimensional de locus de control en salud; en 274 personas con edades entre 19 y 78 años, en un diseño transeccional-causal. Resultados: Por medio de la técnica del análisis discriminante, se obtuvo un Lambda de Wilks de 0.87, asociado a un chi cuadrado (36.24, gl 8, p< 0.05) indicando que los grupos presentan medias estadísticamente significativas en las variables predictoras. Las variables que superaron una carga discriminante mayor al criterio de 0,30 fueron: tiempo con la condición, nivel de instrucción y las estrategias de afrontamiento de tipo evitación. En relación al porcentaje de clasificación se observa que el 71. 2% de los casos fueron clasificado correctamente. Conclusión: mayor tiempo con la condición, menor nivel de instrucción y mayor empleo de las estrategias de tipo evitativas, mayor probabilidad de emplear insulina. El estudio contribuye a eliminar algunos mitos y prejuicios que se tienen acerca del empleo de la insulina como tratamiento farmacológico
Competencias emocionales y bienestar afectivo: un estudio en parejas sentimentales
Authors: Mónaco Estefanía , Tamarit Alicia , Montoya-Castilla Inmaculada
Published: April 2022

Las competencias emocionales se relacionan con una mejor salud física y psicológica, y  mayores niveles de bienestar afectivo. El objetivo del presente trabajo es analizar si las competencias emocionales del compañero sentimental influyen en el bienestar afectivo propio. Participaron en el estudio 68 parejas jóvenes españolas entre 18 y 32 años (N = 136; 52,9% mujeres; M = 22.32 años; DT = 3.15). Respecto a la duración de la relación, participaron parejas entre 6 meses y 8 años y medio de relación (M = 38,58 meses; DT = 24,97). Se estudiaron las características sociodemográficas individuales y de pareja (género, edad, orientación sexual y tiempo de relación) mediante preguntas ad hoc. Se evaluaron las competencias emocionales mediante el instrumento ESCQ y el bienestar afectivo utilizando el SPANE. Se utilizó el paquete estadístico SPSS versión 24.0 para la realización de análisis descriptivos, correlaciones bivariadas y regresiones lineales. De los resultados obtenidos, destacamos que el bienestar afectivo se relaciona tanto con las propias competencias emocionales como con las competencias emocionales del compañero sentimental. El 31.4% de la varianza del bienestar afectivo de una persona está explicada por su propia gestión y regulación emocional, junto con la gestión y regulación emocional de su pareja. Se discute la importancia de fomentar parejas emocionalmente competentes mediante la educación de las personas para mantener vínculos saludables, como forma de aumentar el bienestar afectivo y prevenir problemas de salud.
Alfabetización en salud y salud percibida
Authors: Sala González Marina , Guilabert Mora Mercedes , Carrillo Murcia Irene
Published: April 2022

La Alfabetización en Salud (AES) hace referencia al grado en el que las personas pueden obtener, procesar y entender información básica de salud y servicios que son necesarios para tomar decisiones adecuadas sobre su salud. Estudios previos han relacionado la AES con el nivel de salud. El objetivo de este estudio fue analizar si existían diferencias en AES en función de la salud percibida. Para ello, se llevó a cabo un estudio descriptivo en una muestra de 331 sujetos mayores de 55 años. Para medir el nivel de AES, se les administró el cuestionario European Health Literacy Survey (HLS-EU-q16) y para evaluar el nivel de salud percibido, el cuestionario de Salud General de Goldberg (GHQ-28). El 56% de la población adulta obtuvo niveles de alfabetización en salud suficientes. No se han encontrado diferencias estadísticamente significativas entre el nivel de AES y la salud percibida (p = 0.442). A modo de conclusión, los altos niveles de AES encontrados y la inexistencia de relación entre AES y la salud percibida contrastan con otros los resultados de otros estudios similares. Como limitación del estudio, no se pueden generalizar los resultados ya que la muestra de este estudio son personas mayores de 55 años con un nivel sociocultural medio. Para futuros estudios sería recomendable la utilización de otras pruebas objetivas que midan tanto el nivel de AES como el nivel de salud de los pacientes y el empleo de una muestra con distintos niveles socioculturales.
Efectos del Programa ACOMPAÑA-TÉ sobre los estereotipos hacia la vejez en universitarios
Authors: Brotons Rodes Paula , Lorente Martínez Raquel , Sitges Maciá Esther
Published: April 2022

Introducción: Estudios recientes recomiendan implantar programas educativos que promuevan estereotipos más realistas sobre la vejez y disminuir así las actitudes y comportamientos edadistas.El Programa Acompaña-Té es un curso de voluntariado universitario dividido en un módulo teórico y otro práctico diseñados para eliminar este prejuicio y sensibilizar sobre los problemas a los que las personas mayores tienen que enfrentarse cuando están solas. El objetivo del presente estudio es evaluar si la formación teórica del Programa Acompaña-Té es efectiva para reducir los estereotipos negativos sobre la vejez en un grupo de estudiantes universitarios.Método: Se realizó un diseño pre-post con grupo control, en el que se evaluaron los estereotipos negativos hacia la vejez en el GE (n=20), antes y después del curso de 25 horas, y en el GC (n=20) a través del Cuestionario de Estereotipos Negativos hacia la Vejez (CENVE).Resultados: Los resultados observados indican que en el GE se redujeron significativamente los estereotipos negativos tras la formación, sobre todo en las dimensiones Salud y Carácter-personalidad, estimándose que el 40% de los cambios observados se deben a la formación recibida; mientras que en el GC no se observaron cambios estadísticamente significativos.Conclusiones: La formación específica en temas relacionados con el envejecimiento ha demostrado ser efectiva para reducir los estereotipos negativos hacia las personas mayores en estudiantes universitarios, por lo que programas formativos como Acompaña-Té pueden ser intervenciones recomendables para reducir el edadismo y crear sociedades más inclusivas. Palabras clave: Edadismo, estudiantes, formación, voluntariado universitario.
Experiencing the cancer of their husbands: reports of the wives
Authors: Silva Breno César Almeidaf , Santos Manoel Antônio , Oliveira-Cardoso Érika Arantes
Published: April 2022

Oncological disease affects the whole family, especially the caregiving member, most of the time the woman. The aim of this study was to understand the experiences of wives whose husbands are being treated for hematological cancer. A qualitative, cross-sectional study was carried out with ten wives, aged between 25 and 63 years. A semi-structured interview script and a sociodemographic form were used. It was found that the diagnosis caused many mourning, ambivalent feelings, and the need for family rearrangements. Faith was the main source of support for coping and accepting the disease. We conclude that the illness of the husband triggered the need to learn new skills, and that despite the suffering it was an opportunity to re-signify life.
Breast Cancer Rehabilitation Services in South Africa and Survivor Experience of These Services in Two Dedicated Cancer Units
Authors: Motsoeneng Portia M. , Beutel Anita , Burgess Theresa L. , Naidoo Niri , Stewart Annemie , Shamley Delva
Published: April 2022

Purpose Integrated rehabilitation health care pathways are implemented to meet both physical and clinical needs of breast cancer survivors as they transition from medical treatment to long term survivorship. The aim of this study was to assess current South African upper limb rehabilitation service provision, and perspectives of these from health professionals and breast cancer survivors.Methods A sequential explanatory mixed-methods design informed this study. Service provision was evaluated via an online survey questionnaire completed by health practitioners working in public and private breast cancer units. Focus groups were conducted with both public health practitioners providing the services and breast cancer survivors accessing the services. Results This study has revealed a dearth of rehabilitation services for breast cancer survivors in the public health sector of South Africa. Data reveal an overstretched, understaffed and poorly trained public health sector, unable to deliver adequate upper limb services to breast cancer survivors. Focus group data suggests that this is due to financial austerity rather than poor recognition of the need. Limited patient education is driving poor upper limb outcomes and barriers to change in exercise behaviour.Conclusion Current South African upper limb rehabilitation services do not cater for the needs of breast cancer survivors, leading to poor health outcomes.
Effects of land use types and soil depths on soil organic carbon and total nitrogen stocks of Karacabey floodplain forests in northwest Turkey
Authors: SARIYILDIZ TEMEL , AYGUN DERYA OZCELIK , PARLAK SALIH , TANI MERT
Published: April 2022

To evaluate soil organic carbon (SOC) and total nitrogen (TN) stocks of ash, alder and oak tree stands in Karacabey floodplain forest and adjacent Calabrian pine forest, grassland, cropland and sand dune in relation to soil depths (0-130 cm), a study in three replicate sites for each tree and the adjacent sites was carried out in northwest Turkey. The results indicated that among the tree species, alder stands had the greatest SOC (3.97%) and TN (%0.328) and total accumulation of SOC (405 Mg ha-1) and TN (34.4 Mg ha-1), followed by ash tree (%3.11, %0.302, 393 Mg ha-1 and 26.2 Mg ha-1 respectively) and oak (%2.43, %0.220, 293 Mg ha-1 and 28.6 Mg ha-1 respectively). However, the grassland showed the highest cumulative SOC densities within 0-130 cm depth (678 Mg ha-1) compared to the tree species. It also showed higher TN densities (27.5 Mg ha-1) than the ash tree and the Calabrian pine stands, whereas lower than the alder and oak stands. The sand dunes showed the lowest SOC and TN values. Compared to the soil depth of 0-30 cm, mean SOC and TN stored in 30–130 cm soil depth accounted for 58% and 40% in ash stands, 41% and 45% in alder stands, 52% and 56% in oak stands, 57% and 66% in Calabrian pine stands respectively. Thick alluvial soil and dry climate in the region could be responsible for the better root system development, and thus much higher SOC and TN stocks into deeper soil layers.