bluuebunny/crossref_metadata_2025 huggingface dataset:
Responsibility in Physical Culture and Sports
Authors: Kovalenko Ekaterina , Tydykova Nadezhda
Published: October 2022

The present article introduces an authentic interpretation of sports responsibility. Responsibility in the sphere of sports and physical culture is a legal responsibility, as independent as criminal, administrative, disciplinary, civil, and other types. The system-structural method made it possible to substantiate this independence and distinguish it from other types of legal responsibility. The authors used methods of critical analysis to question those publications that declare the impossibility of classifying sports responsibility as legal. They also conducted a comparative analysis of international legal methods to adopt the positive experience of other countries in terms of the codification of sports legislation as a foundation for the Sports Code of the Russian Federation. The Code would consolidate the main provisions on sports responsibility. The research expands the scientific understanding of sports law and provides material for legislative activities.
Stakeholder engagement for sustainable water supply management: what does the future hold?
Authors: Langsdale Stacy M. , Cardwell Hal E.
Published: October 2022

Sustainable water supply and water resource management relies on effectively engaging stakeholders in decision making. With water conflicts increasing due to stressors such as population growth, climate change, and aging infrastructure, stakeholder engagement holds the promise to improve decisions, save time and money, and improve relationships between governing bodies and stakeholders. This opinion paper reviews the benefits of engaging stakeholders in water supply management decision-making, assesses the current state of the practice, and predicts future trends in the North American setting. The current use of technology will undoubtedly continue, allowing water managers to engage more stakeholders and engage them more substantively. We predict increased roles for the private and nongovernmental sectors in stakeholder engagement, taking place at different scales, but with a focus on the local level. Evaluating the benefits and effectiveness of engagement processes will help justify the investments, and also support practitioners to determine the most appropriate tools and techniques. Finally, foundational principles of open communication, building and maintaining trust, and ethical decision-making must be placed front and center. We see continued growth in the importance, tools, and application of stakeholder engagement as water managers and the communities they serve to strive towards sustainability.
Topical Advances in Mucoadhesive Ocular Drug Delivery System
Authors: Billowria Koushal , Sandhu Navjot Kaur , Singh Baljinder
Published: October 2022

The current article mainly highlights mucoadhesive drug delivery with merits like the prolonged
holding time at the action site and also provides a controlled rate of drug release for improved
therapeutic outcomes. Moreover, mucosal delivery can eliminate problems of the conventional oral
route, such as first pass metabolism as well as acid degradation. However, the eye has unique anatomy
and physiology that can cause hindrance and challenges in comparison to the other organs of the body.
Additionally, conventional delivery vehicles like solutions, suspensions, and ointments have many demerits
such as rapid precorneal clearance, subject variability, drainage, and uncontrolled release from
the dosage form. Therefore, novel pharmaceutical ophthalmic formulations like gels, nanosuspensions,
nano-particles, liposomes, microemulsions, iontophoretic dosage forms, and ocuserts were tried and
tested in the past few years for ophthalmic delivery. These novel delivery products provide enhanced
solubility and bioavailability in a controlled manner to overcome conventional demerits. Here in this
review, we have summarized the improvement of drug studies that are currently underway for eye drug
carriers, along with stages and important aspects of novel drug delivery to the eye.
Predicting the Secondary Structure of Proteins: A Deep Learning Approach
Authors: Mehrotra Deepti , Kathuria Charu , Misra Navnit Kumar
Published: October 2022

Background:

The machine learning computation paradigm touched new horizons with the development of deep learning architectures. It is widely used in complex problems and achieved significant results in many traditional applications like protein structure prediction, speech recognition, traffic management, health diagnostic systems and many more. Especially, Convolution neural network (CNN) has revolutionized visual data processing tasks.

Objective:

Protein structure is an important research area in various domains extending from medical science, health sectors to drug designing. Fourier Transform Infrared Spectroscopy (FTIR) is the leading tool for protein structure determination. This review aims to study the existing deep learning approaches proposed in the literature to predict proteins' secondary structure and to develop a conceptual relation between FTIR spectra images and deep learning models to predict the structure of proteins.

Methods:

Various pre-trained CNN models are identified and interpreted to correlate the FTIR images of proteins containing Amide-I and Amide-II absorbance values and their secondary structure.

Results:

The concept of transfer learning is efficiently incorporated using the models like Visual Geometry Group (VGG), Inception, Resnet, and Efficientnet. The dataset of protein spectra images is applied as input, and these models act significantly to predict the secondary structure of proteins.

Conclusion:

As deep learning is recently being explored in this field of research, it worked remarkably in this application and needs continuous improvement with the development of new models.
Would the Development of a Multitarget Inhibitor of 3CLpro and
TMPRSS2 be Promising in the Fight Against SARS-CoV-2?
Authors: dos Santos Nascimento Igor José , de Moura Ricardo Olimpio
Published: October 2022

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2), responsible for generating
COVID-19, has spread worldwide and was declared a pandemic by the World Health Organization
(WHO) on 11 March 2020, being responsible for various damages to public health, social life,
and the economy of countries. Its high infectivity and mutation rates have stimulated researchers and
pharmaceutical companies to search for new therapies against this disease. These efforts resulted in
several vaccines and the identification of Molnupiravir as an oral treatment for this disease. However,
identifying new alternatives and critical information is necessary to fight against this devastating
agent. The findings in recent years regarding the structure and biochemistry of SARS-CoV2 are remarkable.
In anti-CoV drug discovery, various targets, such as structural, non-structural, and hostrelated
proteins are explored. In fact, 3CLpro is the most used among non-structural proteins since this
protease cleaves peptide sequences after the glutamine residue, and no human protease has this function.
This makes this macromolecule an excellent drug target for discovering new compounds. Another
promising target is the transmembrane protease serine 2 (TMPRSS2). Recent studies point to
TMPRSS2 as one of the main targets responsible for viral entry related to the cleavage of the S protein.
Similar to cathepsins, TMPRSS2 is also responsible for cleaving the spike protein SARS-CoV2,
which binds to the ACE2 receptor. Thus, TMPRSS2 is one of the targets that may represent new
alternatives in treating SARS-CoV2. In this context, would discovering a multitarget inhibitor be the
new strategy in searching for drugs against SARS-CoV2? For many years, new drug discovery was
based on the "one drug, one target" premise, where the biological action is related to interactions
with only one biological target. However, this paradigm has been overcome as new evidence of multiple
mechanisms of action for a single drug. Finally, this review will present a perspective on drug
design based on a multitarget strategy against 3CLpro and TMPRSS2. We hope to provide new horizons
for researchers worldwide searching for more effective drugs against this devastating agent.
A Comprehensive and Critical Review on Analytical and Bioanalytical methods for Metformin Hydrochloride, Dapagliflozin, and Saxagliptin
Authors: Desai Saloni , Maradia Rajnikant Bhikhubhai , Suhagia Bhanubhai N
Published: October 2022

New antidiabetic drug combination Metformin Hydrochloride, Dapagliflozin, and Saxagliptin have been recently approved for type II diabetes. This is marketed by Takeda Pharmaceuticals under the brand name Qternmet XR. Although different analytical and bioanalytical methods using different techniques such as liquid chromatography, high-performance liquid chromatography, high-performance thin-layer chromatography, gas chromatography, spectrophotometry, spectrofluorimetric methods coupled with ultraviolet, fluorescence, mass, or tandem-mass spectrometry detection have already been developed for the determination of Metformin Hydrochloride, Dapagliflozin, and Saxagliptin. Sensitive, cost-effective, and more optimized methods are yet required. Therefore, this review summarizes the main analytical and bioanalytical aspects regarding not only simultaneous estimation but also stability-indicating methods, kinetic studies, and impurity analysis for the analysis of proposed drugs in bulk and pharmaceutical dosage forms. Thus, this review gathers, for the first time, important background information on all analytical and bioanalytical methods that have been developed and applied for the determination of Metformin Hydrochloride, Dapagliflozin, and Saxagliptin, which should be considered as a starting point if new techniques are aimed to be implemented for these drugs.
Nanotechnology a Boon for Colorectal Cancer Treatment
Authors: Kriplani Priyanka , Guarve Kumar
Published: October 2022

Background:

Colorectal cancer (CRC) is the third most widely spread tumor among the
human population. It is usually adenocarcinomatous and develops as a polyp on the inner wall of
the colon or rectum which may become malignant with time. Though its treatment is limited, its
early diagnosis and prevention play a better role, thereby decreasing mortality rates.

Objective:

The molecular markers in CRC-affected tissues may play an important role to develop
novel strategies to cure the disease. Nanotechnology consists of both an innovative diagnostic and
therapeutic array of nanomaterials that may be used to target CRC like dendrimers, carbon nanotubes,
nanoparticles, nano-emulsions, etc.

Methods:

Current patents and research covering the nanotechnology used to target and diagnose
CRC is included in the review.

Results:

Nanotechnology is playing a wonderful role in both the treatment and diagnosis of CRC.

Conclusion:

The present review may cover the recent advancements in nanotechnology in the
treatment and diagnosis of CRC.
The Undervalued Acute Leukopenia Induced By Radiotherapy In Cervical
Cancer
Authors: Ma Ruishuang , Guo Jianxin , Ye Xiaoxian , Zhou Jianliang , Guo Shenchao , Lou Pengrong
Published: October 2022

Background:

Myelosuppression is common and threatening during tumor treatment.
However, the effect of radiation on bone marrow activity, especially leukocyte count, has been
underestimated in cervical cancer. The aim of this study was to evaluate the severity of radiotherapy-
induced acute leukopenia and its relationship with intestinal toxicity.

Methods:

The clinical data of 59 patients who underwent conventional radiation alone for cervical
cancer were retrospectively analyzed. The patients had normal leukocyte count on admission, and
the blood cell count, gross tumor volume (GTV) dose, and intestinal toxicity were evaluated.

Results:

During radiotherapy (RT), 47 patients (79.7%) developed into leukopenia, with 38.3%
mild and 61.7% moderate. The mean time for leukopenia was 9 days. Compared with leukopenianegative
patients, leukopenia-positive ones had lower baseline leukocyte count, while neutrophil/
lymphocyte (NLR) and monocyte/lymphocyte (MLR) showed no significance. Logistic regression
analysis indicated that excluding the factors for age, body mass index (BMI), TNM stage,
surgery and GTV dose, baseline leukocyte count was an important independent predictor of leukopenia
(OR=0.383). During RT, a significant reduction was found in leukocyte, neutrophil and
lymphocyte count at week 2 while monocyte count after 2 weeks. Furthermore, NLR and MLR
showed a significant and sustained upward trend. About 54.2% of patients had gastrointestinal
symptoms. However, no significant relevance was noted between leukocyte count as well as
NLR/MLR and intestinal toxicity, indicating leukopenia may not be the main factor causing and
aggravating gastrointestinal reaction in cervical cancer.

Conclusion:

Our results suggest the underrated high prevalence and severity of leukopenia in cervical
cancer patients receiving RT, and those with low baseline leukocyte count are more likely for
leukopenia, for whom early prevention of infection may be needed during RT.
verdade instrumental do pragmatismo de James como critério do método construtivo de C. G. Jung
Authors: Lima Barbugiani Felipe
Published: October 2022

O objetivo geral desta pesquisa foi investigar as influências do pragmatismo de William James na psicologia de C. G. Jung. Os objetivos específicos foram sintetizar as influências epistemológicas do pragmatismo na psicologia complexa e analisar a influência dos pressupostos do método de James com o método construtivo de Jung. Trata-se de uma revisão de literatura crítica e explicativa, fundamentada no método hermenêutico. O artigo introduz noções básicas do pragmatismo e traça a reconstrução histórica das influências epistemológicas do pragmatismo na psicologia de Jung. Em seguida, apresenta as críticas e assimilações que Jung estabeleceu para o pragmatismo na psicologia complexa. Segue, então, pela investigação da relação entre os critérios do juízo espiritual de James com o método construtivo de Jung. O estudo evidenciou que os fundamentos epistemológicos e metodológicos do pragmatismo são relevantes para a psicologia de Jung, com destaque para a concepção da verdade pragmática como critério permanente da psicologia analítica. Pode-se concluir que os critérios do juízo espiritual de James mostram-se de grande relevância para avaliar o fator eficaz na interpretação dos símbolos na prática da psicoterapia proposta por C. G. Jung.
Artificial Intelligence–Driven Serious Games in Health Care: Scoping Review
Authors: Abd-alrazaq Alaa , Abuelezz Israa , Hassan Asma , AlSammarraie AlHasan , Alhuwail Dari , Irshaidat Sara , Abu Serhan Hashem , Ahmed Arfan , Alabed Alrazak Sadam , Househ Mowafa
Published: October 2022

Background

Artificial intelligence (AI)–driven serious games have been used in health care to offer a customizable and immersive experience. Summarizing the features of the current AI-driven serious games is very important to explore how they have been developed and used and their current state to plan on how to leverage them in the current and future health care needs.

Objective

This study aimed to explore the features of AI-driven serious games in health care as reported by previous research.

Methods

We conducted a scoping review to achieve the abovementioned objective. The most popular databases in the information technology and health fields (ie, MEDLINE, PsycInfo, Embase, CINAHL, IEEE Xplore, ACM Digital Library, and Google Scholar) were searched using keywords related to serious games and AI. Two reviewers independently performed the study selection process. Three reviewers independently extracted data from the included studies. A narrative approach was used for data synthesis.

Results

The search process returned 1470 records. Of these 1470 records, 46 (31.29%) met all eligibility criteria. A total of 64 different serious games were found in the included studies. Motor impairment was the most common health condition targeted by these serious games. Serious games were used for rehabilitation in most of the studies. The most common genres of serious games were role-playing games, puzzle games, and platform games. Unity was the most prominent game engine used to develop serious games. PCs were the most common platform used to play serious games. The most common algorithm used in the included studies was support vector machine. The most common purposes of AI were the detection of disease and the evaluation of user performance. The size of the data set ranged from 36 to 795,600. The most common validation techniques used in the included studies were k-fold cross-validation and training-test split validation. Accuracy was the most commonly used metric for evaluating the performance of AI models.

Conclusions

The last decade witnessed an increase in the development of AI-driven serious games for health care purposes, targeting various health conditions, and leveraging multiple AI algorithms; this rising trend is expected to continue for years to come. Although the evidence uncovered in this study shows promising applications of AI-driven serious games, larger and more rigorous, diverse, and robust studies may be needed to examine the efficacy and effectiveness of AI-driven serious games in different populations with different health conditions.
Define “Innovation” in Semantic Field by Means of Textual Research
Authors: Qing Luo , Hexiu Cao
Published: October 2022

Targeting the discursive power of innovation, “innovation” as philosophical category is discovered in textual research that different from “creation” by the subject of “innovation” could only be human or its collective, and the object could only be nonhuman. As the semantic fields of “practice” or “innovation” displayed, innovation is manifested from different perspectives through the notions of “practice”, “creation”, “labor”, “invention”, “discovery” and “establishment”, etc. The essence of “innovation” is the creative practice increased the total amount of benefits, and its essential feature is worthiness reflected from the subjective and objective dimensions.
DETERMINANTS OF POSTNATAL CARE SERVICE UTILIZATION AMONG REPRODUCTIVE AGE WOMEN IN BASSO LIBEN WOREDA, NORTH WEST ETHIOPIA
Authors: HAILU AYCHILUHEM MANAYE , ALAZBIH NEGA MIHRET
Published: October 2022

Objectives: The objective of the study is to assess the determinants of postnatal care service utilization among reproductive age women in Basso Liben woreda.
Methods: The data were collected from a representative sample of 374 populations using systematic sampling technique. The major strategy of the study was mixed approach. In quantitative study, the data were collected using structure questionnaires. The study participants were women of reproductive age (15–49 years) who gave birth in the past 2 years before the study. The dependent variable is utilization of at least one postnatal care visit within 6 weeks of delivery. Bivariate and multivariate analyses were employed to determine the association between dependent and independent variables.
Results: From the total respondents, 37.7% of the mother and 20.3% of newborn had gotten postnatal checkup within the first 6 weeks, respectively. From PNC users, 51.1% of the mother and 47.4% of the newborn had utilized PNC 1 time, respectively. Based on multivariate analysis maternal education, number of ANC follow-up, PNC information before delivery, monthly income, place of delivery, and attendant during delivery have statistically significance association with postnatal health-care service utilization.
Conclusion: The use of postnatal care service utilization is still limited in the study area. Only 37.7% of the mother and 20.3% of newborn had gotten postnatal checkup. Establishing qualified health facility around the area, expanding transport accessibility, and providing vehicles like ambulances that used to take mothers in the health facility are used to improve postnatal care service utilization.
Nursing Assistance for the Hypertensive Elderly: Reflective Approach to Self-Care
Authors: Machado Bruno Abilio da Silva , Santos Samuel Lopes dos , Barbosa Marcela Flavia Lopes , Alves Winícius de Carvalho , Santos Nisiane dos , Ferreira João Costa , Alves Jane de Araújo , Menezes Débora de Jesus dos Santos , Marques Elijane de Jesus Gomes , Costa Karlene Azevedo Urbano , Lucena Monique de Alencar , Júnior Raimundo Nonato da Silva , Silva Wanderson do Nascimento
Published: October 2022

Systemic Arterial Hypertension (SAH) is characterized by high levels of blood pressure in the arterial vessels. Orem's theory of self-care has become an important tool for the prevention of diseases and reduction of morbidity and mortality due to this cause, considering the extrinsic and modifiable factors of the disease. This study aims to reflect on the nursing care of hypertensive elderly people, based on Orem's theory of self-care. This is a study with a qualitative and descriptive approach, theoretical-reflective, from the perspective of Dorothea Orem's theory of self-care. The SciELO library, BDTD and BDENF databases were used. The search period was from February to May 2022, with time delimitation from 2017 to 2022. To guide the search, the DeCS/MeSH were applied: ¬"Nursing Theory OR (Health of the Elderly AND Hypertension OR Nursing Theory" in SciELO and "Nursing Care" OR "Elderly" AND "Nursing Theory" AND "Aging" in BDENF and BDTD, associated with the Boolean operators AND and OR. According to the eligibility criteria, 27 articles were included in this theoretical-reflective study. Orem considers self-care, the execution of actions that the individual initiates and executes in his own interest, in order to maintain life, stay healthy and in function of well-being. Therefore, to make a difference in nursing care to the elderly with SAH, it is essential to connect knowledge from nursing theories, research and clinical practice. As well as, to reflect on the practice of self-care by the elderly, understanding whether it is necessary to intensify the development of research on the subject investigated.
Leprosy in times of the COVID-19 pandemic: An integrative literature review
Authors: Silva Julianne de Area Leão Pereira da , Oliveira Ana Emília Araújo de , Macri Pietra Pierdomenico , Oliveira Wyngryd Melo , Silva Tais Mendes , Dias Hanna Barreto , Dantas Marília Christina Botelho , Santos Hozana Thamyres Pereira , Damasceno Stálin Santos , Serpa Gustavo Samuel de Moura , Júnior Givaldo Paes Ximenes , Galvão Evandra Marielly Leite Nogueira Freitas , Araujo Vanessa Fernanda Silva de , Maslinkiewicz Alexandre
Published: October 2022

Leprosy is a chronic infectious pathology mainly caused by the intracellular pathogen Mycobacterium leprae. This bacterium especially inhabits skin macrophages and Schwann cells of peripheral nerves, causing skin disease and/or neuritis. COVID-19 is a severe acute respiratory disease (SARS-CoV-2), it emerged recently, while the causative agent of leprosy lasts for more than 2,000 years. Thus, the studies were published in the years 2020, 2021 and 2022, being the equivalent of 14.29% in the year 2020, 71.42% in the year 2021 and about 14.29% in the year 2022, most of the works were from Brazil 85.71%, against 14.29% from Nepal. Regarding the results exposed, it is worth noting that, due to the decrease in the underreporting of endemic diseases, such as leprosy, due to COVID-19 infection, concerns have arisen about the diagnosis and treatment of the disease because of the reduction in notification and demand from users. during the pandemic due to social isolation. Among the main issues, we can highlight the increase in the difficulty of access to health and poverty due to the obstruction of non-essential services, which mainly affects those who already live in precarious conditions.
ANKSIOZNOST U DOBA IZBORA: IZBORNO PONAŠANJE GLASAČA U KONTEKSTU RUSKO-UKRAJINSKOG RATA
Authors: Jovic Nikola , Jaksic Ivana , Krstic Miloan
Published: October 2022

Predizborna kampanja uoči izbora 3. aprila 2022. godine odvijala se u specifičnim uslovima. Svega devet dana nakon što je 15. februara 2022. godine predsednik Republike Srbije, Aleksandar Vučić, raspisao prevremene parlamentarne izbore, Ruska federacija izvršila je invaziju na Ukrajinu. Rat koji je trajao je tokom čitave predizborne kampanje, kreirao je specifičan komunikacioni izazov za političke stranke. Osim toga, rat je uticao i na glasače, pobuđujući anksioznost usled eventualnog prelivanja negativnih posledica rata (bezbednosnih, ekonomskih, političkih, emotivnih) na Srbiju. U ovom radu upravo analiziramo uticaj ratom indukovane anksioznosti na izborno ponašanje glasača. Kvantitativni istraživački dizajn podrazumevao je analizu istraživanja javnog mnjenja sprovedenog neposredno nakon održanih izbora. Upitnik postizborne sondaže bio je fokusiran na proveru dve hipoteze o uticaj anksioznosti na izborno ponašanje: (1) preusmeravanje pažnje glasača sa unutarpolitičkih na spoljnopolitičke teme; (2) promenu preferencija glasača kada je u pitanju donošenje odluke za koga će glasati na izborima.
ISTRAŽIVANJA PREDIZBORNOG MNENJA U DOBA ZASTRAŠIVANJA NARODA: POMOĆ U OSMIŠLJAVANJU KAMPANJE ILI SREDSTVO IZBORNE PROPAGANDE
Authors: Mihailovic Vojislav , Mihailovic Srecko
Published: October 2022

Dobitna kombinacija za izbore u demonskoj inkarnaciji gotovo svake oligarhije koja nastoji da se prikaže u demokratskoj verziji, glasi: zastrašivanje + ucene + podmićivanje naroda koji ima pravo glasa. Više je naroda sa pravom glasa koji ima nisku otpornost prema ovoj trijadi, nego naroda kojeg je teško zastrašiti, nego ljudi koji ne daju povoda za ucenu i ljudi koji odbijaju mito. U takvoj konstelaciji odnosa oligarhije i podređenog naroda pitanje je da li je moguće i kako je moguće obavljati društvena istraživanja, i nadasve kakva se istraživanja rade. U stvari, pitanje je da li i koliko se istraživanja svode na sredstvo kojim oligarhija povećava svoju „izbornu moć“ ili su ipak moguća istraživanja koja ispituju šanse demokratije u jednoj autokratskoj državi sa većinom podanika autoritarno orijentisanim. Dakle, kakav je ishod predizbornog sučeljavanja srpske oligarhije, ovdašnjeg autoritarnog naroda i kakvih-takvih istraživača politički konfuznog predizbornog mnenja? U situaciji kada je „duh vremena“ ovog naroda uoči izbora obeležen širokom (pred)izbornom patologijom, pitanje je da li je moguće obavljati korektna mnenjska predizborna istraživanja. Da li se istraživači mogu osloniti na izjave ispitanika koji su zastrašeni, ucenjeni i podmićeni?
Odgovori na ta pitanja traže neke prethodne odgovore: (1) Da li se uopšte može dobiti pristanak na anketu u društvenoj klimi obojeni radom pomenute trijade? Ko su oni koji odbijaju da odgovore na pitanja anketara: šta o njima znamo, ako uopšte nešto znamo? (2) Da li ima istraživača kojima je stalo do korektno i profesionalno izvedenog istraživanja? Ako takvih ima, da li oni mogu da dođu do prilike da realizuju neko istraživanje? Da li ima naručilaca za njihova istraživanja? (3) Ako postoje moćni politički subjekti koji su spremni da zastrašuju, ucenjuju i podmićuju celi glasački narod, zašto objekt tih radnji ne bi bili i sami istraživači, zašto bi baš oni bili izuzetak? Na kraju, tu su i pitanja o tome kako sam zaplašen, ucenjen i podmićen narod vidi mogućnost da iskaže svoje, a ne iznuđeno mišljenje i svoje izborno opredeljenje, a ne ono koje se od njega bezuslovno zahteva? Kakav je odgovor naroda na sve prinude i iznude, uoči izbora i posle izbora?
IZBORNE STRATEGIJE PARTIJA I KANDIDATA ZA PARLAMENTARNE I PREDSEDNIČKE IZBORE 2022. GODINE
Authors: Atlagic Sinisa
Published: October 2022

Autor se u radu bavi osnovnim elementima strategija političkih partija i kandidata u kampanji za parlamentarne i predsedničke izbore u Srbiji 2022. godine – tipovima kampanja, pozicioniranjem, okosnicama i sloganima. U analizi propagandnih poruka, govora i tekstova partijskih predstavnika i kandidata, kao i izbornih programskih dokumenata koristi metodu kvalitativne analize sadržaja kao opštu istraživačku metodu. Nalazi da su izborni ciljevi uglavnom realno određeni i da su u opredeljenju za strategiju kampanje partije i kandidati polazili od dugoročnih strategija političko-propagandnog delovanja. Među posebnim okosnicama u kampanji dominantne su političke i ideološke. Korišćeni slogani su u skladu sa okosnicama i najčešće predstavljaju izraz identifikacije sa državnom zajednicom.
PUBLICITET U MEDIJIMA I ODNOSI SA JAVNOŠĆU KAO ELEMENT STRATEGIJE POLITIČKOG MARKETINGA PARTIJA I KANDIDATA ZA PARLAMENTARNE I PREDSEDNIČKE IZBORE 2022. GODINE
Authors: Vujanovic Jelena
Published: October 2022

Izbor oblika promocije i kreiranje poruka u okviru njih u skladu sa ciljem kampanje čine važan element strategije političkog marketinga. U fokusu ovog rada su odnosi sa javnošću i publicitet u medijima kao oblici promocije u okviru strategije političkog marketinga učesnika na parlamentarnim i predsedničkim izborima u Republici Srbiji 2022. godine. Rad polazi od pitanja koje aktivnosti odnosa sa javnošću i privlačenja publiciteta su partije i kandidati sprovodili, da li je fokus ovih oblika promocije bio na temama i politikama, imidžu kandidata i lidera ili konfrontaciji sa konkurentima, te kako se to uklapa u njihovu cjelokupnu strategiju političkog marketinga. Za potrebe istraživanja analiziraćemo sadržaj svih priloga o akterima kampanje na portalima novinskih agencija Beta i Tanjug u periodu od 11. do 31. marta 2022. godine i prisustvo na naslovnim stranama dnevnih novina, te sprovesti intervjue sa predstavnicima izbornih lista. Istraživanje će se osvrnuti i na pitanje uticaja sukoba u Ukrajini na publicitet učesnika kampanje i mogućnost da sprovedu sopstvene strategije odnosa sa javnošću.
Experiencias significativas en las instituciones educativas: San Francisco de Asís, Gualmatán y Tumac en pandemia
Authors: Jojoa Rodríguez Deyanira del S. , Suárez Bejarano Martha M. , Ortiz Angulo William , Ochoa Guevara Nancy Edith
Published: October 2022

Este artículo hace una radiografía desde las experiencias significativas en pandemia, en las instituciones públicas: San Francisco de Asís, nivel transición B; Gualmatán, nivel transición y básica primaria; y Tumac, media vocacional. En ella se expresan las vivencias desde cada una de las regiones acerca de la forma de adaptarse a las nuevas condiciones de virtualidad y educación remota, ocasionadas por la emergencia sanitaria. En el estudio se utilizan la ruta metodológica cualitativa e instrumentos para la recolección de la información por medio de una entrevista semiestructurada corta con el cuadro de triple entrada, en el que se organizan las categorías e indicadores derivados de las experiencias de investigación, a fin de determinar aquellas que influyen de manera significativa en los estudiantes y sus familias. Las estrategias empleadas por los docentes permiten explorar al interior de los hogares diferentes aprendizajes y la alfabetización en el uso de las Tecnologías de la Información y la comunicación. Por otro lado, la autoevaluación permanente facilita un registro de aprendizajes y comportamientos propios de cada integrante. A pesar de las carencias en conectividad, se logra la comunicación sincrónica y asincrónica de manera constante, la cual influye positivamente en el desarrollo socioemocional de las comunidades educativas durante el tiempo de educación remota.
Airline Ticket Price Prediction
Authors: Babu Dr. B. Sekhar , Venkat Kuppala Mahi , Reddy Janga Manoj , Sai Katragadda Rathna
Published: October 2022

Abstract: A mode of transportation is an airline. It is essential for both domestic and international travel that takes place quickly. They are relatively expensive when compared to other forms of transportation. But our comfort level and journey time will be directly impacted by this price. When more capacity is needed to meet demand, the airline may raise the prices. Data for a certain air route, including parameters like departure time, arrival time, and airways for a specific period, has been gathered to determine the minimum airfare.
Amenable Argumentation Approach
Authors: Carozza Linda
Published: October 2022

This paper summarizes various interpretations of emotional arguments, with a focus on the emotional mode of argument introduced in the multi-modal argumentation model (Gilbert, 1994). From there the author shifts from a descriptive account of emotional arguments to a discussion about a normative framework. Pointing out problems with evaluative models of the emotional mode, a paradigmatic shift captured by the Amenable Argumentation Approach is explained as a way forward for the advancement of the emotional mode and multi-modal argumentation.
Kisceral Argumentation in Law
Authors: Novak Marko
Published: October 2022

Gilbert's kisceral argumentation is, roughly speaking, about arguing based on intuitions. In the forefront of such a (rhetorical) model are arguers and audiences, who resolve disagreements using kisceral arguments. Intuitions as reasons were more important in pre-modern law, when the law was not as explicit, precise, and determinate as today. Law influenced by religion or religious law was a typical example. In our much more secular modern era, intuitions are more or less subordinated to the (legal) logical mode of arguing. However, in tough legal cases, when logic "runs out," it is values that decide them. Not surprisingly, neuroscience and cognitive psychology have shown a strong connection between values and intuition.
COVID-associated non-vasculitic thrombotic retiform purpura of the face and extremities: A case report
Authors: Bunch Connor , Zackariya Nuha , Thomas Anthony , Langford Jack , Aboukhaled Michael , Thomas Samuel , Ansari Aida , Patel Shivani , Buckner Hallie , Miller Joseph , Annis Christy , Quate-Operacz Margaret , Schmitz Leslie , Pulvirenti Joseph , Konopinski Jonathan , Kelley Kathleen , Hassna Samer , Nelligan Luke , Walsh Mark
Published: October 2022

SARS-CoV-2 infection can manifest many rashes. However, thrombotic
retiform purpura rarely occurs during COVID-19 illness. Aggressive
anti-COVID-19 therapy with a high-dose steroid regimen led to rapid
recovery. This immuno-thrombotic phenomenon likely represents a poor
type 1 interferon response and complement activation on the endothelial
surface in response to acute infection.
Perception, evaluation and prediction of the shopping mall building assessment
Authors: Tamburic Jasmina , Vukanic Jovana , Nikolic Vladan
Published: October 2022

The change in the condition of a building over time in the technical terms can be seen as a deteriorating process of aging of the building elements and the loss of original technical performance. In the economic terms, it is the process of changing the value of the facility and new investments in the maintenance of the facility, as well as servicing the system of equipment and installations, during the service life. The technical dilapidation of the building, or of its elements, can lead to unwanted consequences of endangering the lives and property of people, and of the disruption of functional and aesthetic values of the building, which is very important for the fate of shopping malls. With the exhaustion of the technical life of the building, questions and decisions about the revitalization or demolition of the building necessarily arise. The value of the facility decreases over time, and the costs of maintenance and repairs increase. Over time, regardless of the actual condition, the facility and equipment systems become obsolete when the first needs for modernization arise, which entails new costs. The ratio of maintenance costs is constantly growing, until the moment when the level of profitability of further investment in the renovation of the facility and the system is reached, i.e. until the moment of exhaustion of the economic life of the facility. The paper presents the relationship between preventive, reactive and predictive maintenance costs as well as methods of monitoring, prediction and evaluation of the durability condition of shopping mall facilities.
Critique of the concept of nature by Donna Haraway
Authors: Sekulic Nada , Vukanic Jovana , Nikolic Vladan
Published: October 2022

Starting from the fundamental importance that relationship between nature and
culture has in humanities, particularly in relation to the nature of humans,
including intersection with the debate on gender and sex, I examine the
cyber-feminist approach of Donna Haraway. She interprets the concepts of
gender, race, nature, sex as chronotopes, changing products of specific
long-term histories, and not as self-evident data that would be grounded in
biology. By introducing the categories of chronotope (unified space-time),
cyborg (unified machine-mananimal), chthulocene (epoch of productive
cacophony and networking), Haraway deconstructs the dichotomous demarcation
between nature and culture, civilization and savagery, mind and body, male
and female, as well as the boundaries between gender and sex, characteristic
of the history of the humanities and related sciences, as well as of the
history of feminism itself.
Same-sex families in Serbia in times of COVID-19
Authors: Radoman Marija
Published: October 2022

This paper presents a qualitative research on the experiences of same-sex
families in Serbia since the beginning of the kovid-19 epidemic. In Serbia,
same-sex families are not legally recognized, while the law on same-sex
unions has not yet been adopted. The first part of the paper focuses on the
theoretical epistemological assumptions of the research of same-sex families
and LGBTQ+ parenting, while the second part offers an interpretive
phenomenological analysis (IPA) through three case studies. In this paper, I
analyze the experiences related to the family life of three women during and
after the pandemic period, focusing on the wide range of meanings that this
brings with it. The research strives to present the authentic meanings of
the lesbian parents as closely as possible, taking into account the
differences in the perspectives and interpretations of the respondents. The
theoretical and epistemological framework is a phenomenological approach,
and the aim of the paper is not only to analyze and describe the experiences
and meanings that the respondents had during the pandemic period, but
connecting these experiences with the wider socio-cultural and political
context, in order to determine how the context and personal stories are
connected.
Experiences of medical transition in transgender people in Serbia: From affirmation of identity to institutionalized violence
Authors: Vidic Jelena , Stankovic Biljana , Dzamonja-Ignjatovic Tamara
Published: October 2022

Transgender people are one of the most stigmatized social groups. They are
experiencing institutional stigma and stigma on individual psychological
level through different medical and legal procedures specific to their
group. Though gender confirmation surgeries have been performed in Serbia
for more than three decades, research on experiences and ways in which
transgender people give meaning to the process is lacking. This topic became
even more prominent due to significant changes in the area of
depychopathologization of gender diversity and individualization of the
medical gender confirmation process. This paper presents the experiences of
transgender people in Serbia throughout the medical gender confirmation
process and analyses the ways in which transgender people experience the
process and give meaning to it, aiming to draw attention to certain
problematic practices still present in the local institutional context. We
used semi-structured interviews to collect data. Our approach is
qualitative, based on interpretative phenomenological analysis. The sample
consists of 12 transgender people age 23 to 48 (8 trans men and 4 trans
women). Results indicate the great psychological and practical significance
of the medical transition, and diversity in their needs when it comes to
surgical interventions, implicating the importance of the easier access to
the treatment and the individualization of treatment.
Optimality conditions for isoperimetric continuous - time optimization problems
Authors: Vicanovic Jelena
Published: October 2022

In this paper we deal with a nonsmooth case of isoperimetric convex continuoustime programming problem with inequality integral constraint and phase constraint, defined in L?([0, T],Rn). In order to obtain necessary optimality conditions for this problem, we will use a theorem of the alternative from [15] as a main tool.
Success rate, treatment duration, and pain perception in the management of palatally impacted canines using the K9 and Ballista spring: a randomized clinical trial
Authors: Verma Sanjeev , Singh Satinder Pal , Verma Raj Kumar , Kumar Vinay , Singh Sombir , Bhupali Nameksh Raj
Published: October 2022

Objectives

To evaluate the success rate, treatment duration, and pain perceived during forced eruption of maxillary palatally impacted canines using the K9 and Ballista springs.

Materials and Methods

Thirty unilateral palatal canine impactions of moderate and difficult category as determined by KPG index (score between 10 and 19) were enrolled. Group 1 comprised canine impactions managed with K9 springs, and Group 2 comprised Ballista springs. Block randomization and opaque sealed envelopes were used for allocation. The success rate and treatment duration (application of force to ligation of the impacted canine into the initial alignment archwire) were recorded. Pain perception was evaluated on a 10-point visual analogue scale (VAS) and modified McGill Pain Questionnaire. Chi-square test and Mann-Whitney U-test were used to compare the groups.

Results

The success rate for eruption of palatally impacted canines was 100%. The average treatment duration was 296.13 ± 96.45 days and 311.93 ± 94.34 days, respectively for Group 1 and Group 2. VAS scale scores for pain were greater for Group 2 compared to Group1, and the differences were statistically significant at all time intervals except at T1. The frequency of none and mild pain was significantly greater at all time intervals in both groups.

Conclusions

The impacted canines of moderate and difficult category were erupted with a 100% success rate and similar treatment duration with both interventions. The pain scores of Ballista springs were greater after 24 hours of force application.
Analysis of overcorrection to be included for planning clear aligner therapy: a retrospective study
Authors: Palone Mario , Pignotti Andrea , Morin Eugenia , Pancari Carolina , Spedicato Giorgio Alfredo , Cremonini Francesca , Lombardo Luca
Published: October 2022

Objectives

To provide clinical information on overcorrection to be included in the initial digital setup to make clear aligner therapy (CAT) more efficient.

Materials and Methods

Prescription data for 150 patients (80 women and 70 men; mean age 33.7 ± 12.7 years) treated successfully with CAT (F22 Aligners, Sweden & Martina, Due Carrare, Italy) and requiring only a single, minimal finishing phase were acquired retrospectively. The inclusion criteria were Class I dental malocclusion with only minimal crowding (≤3 mm), 12–20 aligner steps per arch, no use of auxiliaries or interarch elastics, and rotations ≤25° for round-shaped teeth. The prescribed and corrective movements to be achieved in the main and finishing treatment phases, respectively, were quantified by the dedicated clear aligner setup software. The magnitudes of inclination (buccal-lingual crown tipping), angulation (mesial-distal crown tipping), rotation, intrusion, and extrusion were extracted and analyzed by tooth type, maxilla and mandible, and both arches. Descriptive statistics, that is, mean, standard deviation, and percentage, were calculated for each movement investigated. Classification and regression trees (CART) were generated using the model-based recursive partitioning approach, and the corrective movements were correlated with respect to both the amount of the movements prescribed and the tooth type. Statistical significance was set at 5%.

Results

Inclination and rotation required the greatest correction, whereas angulation, intrusion, and extrusion required only minimal correction. Expressed as a percentage of prescribed movement, mean corrective movements were 20.5% for inclination, 14.5% angulation, 28.4% rotation, 11.7% extrusion, and 22% intrusion. According to CART, all corrective movements except extrusion depended on both tooth type and the magnitude of prescribed movement.

Conclusions

To achieve more efficient CAT, approximately 20% overcorrection should be added to the initial planning phase when planning challenging movements such as inclination and rotation.
Coronary Spasm During Postoperative Sedation With Dexmedetomidine
Authors: Sato Yu , Matsumura Tomoka , Abe Yushi , Kutsumizu Chihiro , Maeda Shigeru
Published: October 2022

This is a case report of an 81-year-old woman who underwent tracheostomy, bilateral cervical dissection, partial tongue resection, radial forearm free flap reconstruction, and split-thickness skin grafting under general anesthesia. After successful surgery, she was moderately sedated postoperatively with intravenous dexmedetomidine (DEX) and fentanyl. The fentanyl was discontinued 5 hours postoperatively. Eight hours after the operation, an atrioventricular junctional rhythm, a 2-mm elevation of the ST segment, and biphasic T waves were detected in lead II that lasted approximately 3 minutes. Hypotension and bradycardia were observed simultaneously with the abnormal electrocardiogram. The next day, a cardiologist examined the patient and suggested that coronary spasm had occurred based on those findings. The transient coronary spasm was likely caused by a combination of various factors including surgical stress and altered autonomic function. However, it is possible that stimulation of α-2 adrenergic receptors induced by DEX may also be linked to the coronary vasospasm that occurred.
Methemoglobinemia Induced by Prilocaine in a Child With Noonan Syndrome
Authors: Takagi Saori , Ando Shinnosuke , Kono Ryoko , Oono Yuka , Nagasaka Hiroshi , Kohase Hikaru
Published: October 2022

Limited information is currently available on methemoglobinemia caused by the administration of prilocaine in children undergoing dental procedures in Japan. This case report presents the development of methemoglobinemia due to prilocaine overdose. The patient was a female aged 5 years 8 months with Noonan syndrome who also had pulmonary valve stenosis and hypertrophic cardiomyopathy. She presented with severe dental caries affecting 12 total teeth and required general anesthesia due to a lack of cooperation during dental treatment. General anesthesia was performed, during which 3% prilocaine with 0.03 IU/mL felypressin was administered intraoperatively via infiltration. Her SpO2 gradually decreased after 30 minutes, and cyanosis was observed postoperatively. Several assessments including a 12-lead electrocardiogram, an anteroposterior chest radiograph, and venous blood gas analysis were performed to identify potential causes. However, there were no indications of acute respiratory or cardiovascular abnormalities. It was noted that a total of 192 mg prilocaine was administered during the procedure, and methemoglobinemia was suspected to have developed because of overdose. Further testing revealed an elevated serum methemoglobin of 6.9%, supporting methemoglobinemia as the cause of her decreased SpO2. In dental procedures that require the use of prilocaine to treat multiple teeth, particularly for pediatric patients, it is important to carefully manage prilocaine dosing, as an overdose may lead to methemoglobinemia.