bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Preregistration and P-Value Patterns on Trust in Psychology and Biology Research
Authors: Conry-Murray Clare , Mcconnon Ann , Bower Morgan
Published: June 2022

The replication crisis has shown that research in psychology and other fields including biology is not as robust as previously thought. In response, methods have been introduced to address the problem and increase reproducibility, including two methods that are the focus here: (1) preregistration of study hypotheses and methods, and (2) analysis of whether p-hacking may have occurred through patterns of p-values. Each is easy to find, even in short summaries of research, but do consumers of research recognize these indicators as evidence of trustworthiness? In the current study, we examined how professionals (n = 111), researchers (n = 74) and undergraduate students (n = 78) judged the trustworthiness of short descriptions of research in their field, which varied in terms of whether there was a reference to a preregistration or evidence of potential p-hacking. Overall, participants trusted studies less when they were not preregistered. Researchers and professionals, but not students were sensitive to evidence of p-hacking. We suggest that education about questionable research practices like p-hacking and hypothesizing after the results are known needs to be improved.
Active and inactive oil and gas sites contribute to methane emissions in western Saskatchewan, Canada
Authors: Vogt Judith , Laforest Justin , Argento Mark , Kennedy Sarah , Bourlon Evelise , Lavoie Martin , Risk David
Published: June 2022

The oil and gas industry is Canada’s largest contributor to national methane (CH4) emissions. To quantify the input of active and inactive (suspended and abandoned) oil and gas infrastructure to regional CH4 budgets, we conducted truck-based measurements (transect-based and OTM 33A) with a greenhouse gas analyzer, complimented with optical gas imaging at oil-producing sites of Saskatchewan, including understudied regions. We found that inactive sites regionally accounted for roughly 43% of total measured CH4 emissions in Lloydminster, 9% in Kindersley, and 0% in Swift Current. Thus, CH4 emissions from oil production in southwestern Saskatchewan are underestimated by almost 25% if emissions from inactive sites are ignored. Measured mean CH4 emissions of actively producing oil and gas infrastructure in Lloydminster were at least 50% lower (36 ± 7 m3/day) than found in previous studies potentially due to declines in production schemes, effective implementation of emission reduction approaches, or spatial differences between sampled sites. Unlike previous studies, measured emissions in Lloydminster were lower than reported values (147 ± 10 m3/day). In contrast, measured emissions in Kindersley (64 ± 17 m3/day) and Swift Current (23 ± 16 m3/day) were close to reported emissions despite observed tank vents and unlit flares. Unlit flares emitted at least 3 times more CH4 than other infrastructure types and were the “super-emitters” in this study. Currently, provincial and federal regulations target only active infrastructure, but regulators may consider extending regulations to inactive sites where data suggest significant emission reduction potential.
THE SOCIAL DEVELOPMENT APPROACH TO SOCIAL WORK IN HEALTH CARE
Authors: Petersen Laetitia , Pretorius Edmarie
Published: June 2022

Social work in health care delivers essential services to South Africa’s vulnerable populations. The social development approach attempts to address inequalities and uplift vulnerable people. An explanatory-sequential mixed methodological study explored the application of the social development approach to social work in health care in the Gauteng Department of Health. The findings indicated that social workers in health care deliver a diverse service in attending to patients’ needs and are ideally situated to address and implement the social development approach. However, challenges are experienced in the absence of strategic policies regarding the implementation of the social development approach in health care. Keywords: Gauteng Department of Health, health care reform, health care settings, social development approach, social work in health care, transformation
EXPLORING THE PERCEPTIONS OF CORRECTIONAL SERVICE PROVIDERS AND ELDERLY PAROLEES OF POST-INCARCERATION SOCIAL WORK PROGRAMMES IN ETHEKWINI METROPOLITAN
Authors: Nduli Sethenjwa Bonny , Mthembu Maud
Published: June 2022

This qualitative study explored the perceptions of correctional service providers and elderly parolees regarding post-incarceration social work programmes. Primary data were drawn from semi-structured interviews conducted with 15 (n=15) elderly parolees, three (n=3) social workers and two (n=2) correctional officials from South Africa’s Department of Correctional Services. The findings of this study indicated that correctional social work programmes often did not prioritise the unique needs of elderly parolees; the study findings also revealed the urgent need for developing social work programmes that cater exclusively to the needs of elderly parolees. Moreover, the study found the need for developing ongoing training programmes to strengthen reintegration services offered to the elderly cohort, and finally, the study also revealed that the increase in the number of elderly offenders being released on parole impacted negatively on the responsiveness of social work post-incarceration programmes. This article concludes by offering recommendations to the Department of Correctional Services and social workers working in community correctional centres. Keywords: community correctional centres, correctional service providers, elderly parolees, post-incarceration, reintegration services, social work programmes
Prolonged APTT and autoimmune overt hypothyroidism identified postpartum: a case report
Authors: Hjelm Lundgaard Maja , Carlé Allan , Birgitte Christiansen Ulla , Sørensen Anne , Risom Kristensen Søren , Andersen Stine Linding
Published: June 2022

Introduction

Thyroid disorders have been linked to abnormalities in the coagulation system, and a hypocoagulant state has been proposed in hypothyroidism. The assessment of thyroid function is, however, not routinely recommended as part of the assessment for coagulation disorders.

Case presentation

We present a 32-year-old woman who had no history of thyroid disease and who recently gave birth preterm because of severe preeclampsia and intrauterine growth restriction. Due to severe placental dysfunction, she underwent a routine biochemical assessment of the coagulation system 6 months postpartum, and a prolonged activated partial thromboplastin time (APTT) (43 s) was identified along with a low level of coagulation factor VIII (0.44 IU/mL), and a low level of von Willebrand factor (vWF) antigen (0.35 IU/mL), vWF activity (0.38 IU/mL) as well as reduced generation of thrombin. The assessment of thyroid function in the patient identified autoimmune, overt hypothyroidism with a thyroid-stimulating hormone (TSH) concentration of 139 mIU/L, low levels of the peripheral thyroid hormones (total thyroxine: 43 nmol/L, total triiodothyronine: 0.9 nmol/L), and high levels of thyroid peroxidase antibodies (296 U/mL) as well as thyroglobulin antibodies (927 U/mL).

Conclusion

In this case, prolonged APTT provided a diagnostic clue for the assessment of thyroid function in a young woman with a recent history of severe placental dysfunction. The identification of autoimmune, overt hypothyroidism emphasizes that measurement of TSH may be of clinical importance in cases of unexplained prolonged APTT or other biochemical signs of abnormalities in the coagulation system.

Established facts

Hypothyroidism has been associated with alterations of the coagulation system suggesting a hypocoagulant state.

At present, measurement of thyroid-stimulating hormone is not routinely recommended as part of the assessment for coagulation disorders.

Novel insights

In this case, biochemical assessment of the coagulation system was routinely performed following a pregnancy complicated by severe placental dysfunction.

Overt hypothyroidism of autoimmune origin was identified secondary to prolonged activated partial thromboplastin time (APTT) postpartum along with low levels of coagulation factor VIII, von Willebrand factor, and thrombin generation.

Measurement of thyroid-stimulating hormone may be considered in cases of unexplained prolonged APTT.
Assessing the influence of Rural –Urban migration on human trafficking in Rwanda
Authors: Gacinya John , Kirimi Elijah
Published: June 2022

Throughout the world, movement of people has been taking place from the rural characterized by deprivation to the urban mostly endowed with social amenities and economic advancement. As rural-urban influx continues, urban infrastructure is put on strain and this culminates into urban poverty which is a favorable condition for human trafficking. The study indicates that there is a close relationship between rural-urban migration and human trafficking in Rwanda. This is clearly shown by domestic workers, girls and women who flock the urban with hopes for economic advancement but only to suffer prostitution and human trafficking at a later stage. Lee’s migration theory which used push and pull factors was applied to explain the relationship between rural-urban migration and human trafficking. About 7,000 children left the rural to the urban and are potential recruits for human trafficking. Data was collected and analyzed by use of documentary method. Findings indicate there a very close relationship between rural-urban migration and human trafficking. To reduce human trafficking one needs to reverse ruralurban migration by applying rural development projects such as creation of basic social and economic infrastructure as well as promotion of non-farm income sectors in rural areas.
Про підсумки виконання науково-технічних проєктів установ НАН України у 2021 році
Authors: Богданов Вячеслав Леонідович
Published: June 2022

Доповідь присвячено підсумкам виконання науково-технічних проєктів установ НАН України в 2021 р. Наведено приклади отриманих результатів, які свідчать, що така форма організації та фінансування науково-технічних робіт виявилася досить ефективною і може сприяти, поряд з виконанням госпдоговірної тематики та контрактів із закордонними замовниками, комерціалізації науково-технічних розробок Академії.
Parental Depression Screening in Pediatric Health Care Settings: A Scoping Review
Authors: Hunt Ava Marie , Uthirasamy Nila , Porter Sallie , Jimenez Manuel E.
Published: June 2022

BACKGROUND AND OBJECTIVES

Parental depression affects as many as 1 in 5 US families. Pediatric professionals can play an important role in detecting parental depression, yet most studies on parental depression screening focus only on the postpartum period. The authors performed this scoping review to understand the existing literature on parental depression screening outside the postpartum period (child >12 months old) and to identify knowledge gaps.

METHODS

Sources for this research include PubMed, CINAHL, SCOPUS, Web of Science, and APA Psych Info. We included English language papers concerning screening for maternal and/or paternal depression or mood disorders outside of the postpartum period by pediatric clinicians or in a pediatric health care setting. Extracted variables included publication year, title, author(s), country, geographic setting, clinical setting, child age range (in years), parental focus, sample size, study type, approach, screening instrument(s), and findings.

RESULTS

Forty-one papers were included. The proportion of positive parental depression screens was consistently high across the included studies. Relatively few structured screening programs outside of the postpartum period were identified, especially for fathers. The included studies suggest that screening can be accomplished in pediatric settings, but appropriate referral and follow-up of positive screens poses a major challenge. This review was limited to English language papers concerning parental depression outside of the postpartum period.

CONCLUSIONS

These findings suggest that screening for parental depressive symptoms outside the postpartum period could identify families in need of support. Research is required to identify best practices for referral and follow-up of parents who screen positive.
Decreasing Misdiagnoses of Urinary Tract Infections in a Pediatric Emergency Department
Authors: Ostrow Olivia , Prodanuk Michael , Foong Yen , Singh Valene , Morrissey Laura , Harvey Greg , Campigotto Aaron , Science Michelle
Published: June 2022

BACKGROUND AND OBJECTIVES

Urinary tract infection (UTI) is a common diagnosis in the emergency department (ED), often resulting in empirical antibiotic treatment before culture results. Diagnosis of a UTI, particularly in children, can be challenging and misdiagnosis is common. The aim of this initiative was to decrease the misdiagnosis of uncomplicated pediatric UTIs by 50% while improving antimicrobial stewardship in the ED over 4 years.

METHODS

By using the Model for Improvement, 3 interventions were developed: (1) an electronic UTI diagnostic algorithm, (2) a callback system, and (3) a standardized discharge antibiotic prescription. Outcome measures included the percentage of patients with UTI misdiagnosis (prescribed antibiotics, but urine culture results negative) and antibiotic days saved. As a balancing measure, positive urine culture results without a UTI diagnosis were reviewed for ED return visits or hospitalization. Statistical process control and run charts were used for analysis.

RESULTS

From 2017 to 2021, the mean UTI misdiagnosis decreased from 54.6% to 26.4%. The adherence to the standardized antibiotic duration improved from 45.1% to 84.6%. With the callback system, 2128 antibiotic days were saved with a median of 89% of patients with negative culture results contacted to discontinue antibiotics. Of 186 patients with positive urine culture results with an unremarkable urinalysis, 14 returned to the ED, and 2 were hospitalized for multiresistant organism UTI treatment.

CONCLUSIONS

A UTI diagnostic algorithm coupled with a callback system safely reduced UTI misdiagnoses and antibiotic usage. Embedding these interventions electronically as a decision support tool, targeted audit and feedback, reminders, and education all supported long-term sustainability.
СИНТЕЗ ЦЕОЛІТУ З ПРИРОДНОЇ ГЛИНИ І ЗОЛИ РИСОВОГО ЛУШПИННЯ В ЯКОСТІ ПЕРСПЕКТИВНОГО ФОТОКАТАЛІЗАТОРА ДЛЯ ЗМЕНШЕННЯ ЗАБОРОНЕНОЇ ЗОНИ ДІОКСИДУ ТИТАНУ
Authors: Сюкрі Сюкрі , Факрі Ахмад , Сафні Сафні , Норта Тетра Оллі
Published: June 2022

In this study, we have utilized clay from Pariaman, Indonesia enriched with silica from rice husk ash to produce zeolite through a hydrothermal process. The resulting zeolite is then composited with the most common semiconductor photocatalyst, an anatase titanium oxide, to increase the semiconductor efficiency in terms of particle distribution and light sources activation. From X-Ray Fluorescence (XRF) measurement, it can be seen that the Si/Al mole ratio in the clay has been successfully increased from 1.8 to 2.0. These data are strengthened by the results of X-Ray Diffraction (XRD) analysis which shows the formation of zeolites of several types consisting of zeolite faujasite, P1, sodalite, X, and nu-6. When the synthesized zeolite is mixed with titania anatase, a composite is formed as evidenced by FTIR analysis with the appearance of Si-O-Si and Si-O-Al absorption bands for zeolite and Ti-O-Ti from titania. This zeolite has been shown to reduce the bandgap energy of titanium oxide after the two materials have been composited. Measurements with Ultraviolet-Visible Diffuse Reflectance Spectroscopy (UV-Vis DRS) showed that the TiO2-anatase band gap decreased by about 20 %, from 3.20 to 2.56 eV allowing theoretically the composite to be considered as a promising photocatalyst.
ОБҐРУНТУВАННЯ ВИБОРУ МОЛОЧНОЇ СИРОВИНИ ДЛЯ ОДЕРЖАННЯ ДОБАВОК ДІЄТИЧНИХ СЕЛЕН-БІЛКОВИХ ЗА ПОКАЗНИКАМИ ЇЇ СТРУКТУРИ
Authors: Применко Владислав Г. , Сефіханова Катерина A. , Геліх Анна O. , П. Головко Микола , Василенко Ольга О.
Published: June 2022

Мета. Обґрунтувати вибір сировини для селен-білкових дієтичних добавок, а саме виду сироватки в якості матриці для їх виробництва, і визначити подальшу можливість використання добавок в технології кулінарних виробів спеціального призначення. Методи. Визначення структурних характеристик зразків молочної сироватки проводили за допомогою електронного мікроскопа Quattro ESEM при збільшенні в 10000 і 1000 разів. Аналіз кількісних і розмірних характеристик досліджуваних частинок проводився з використанням програми MS Excel. Одержані результати. Обґрунтовано спосіб і режим згущення сироватки, проведено аналіз однорідності зразків сироватки безлактозної і з її вмістом при різних режимах згущення. Визначено співвідношення складових селен-білкових добавок і характер взаємодії їх компонентів. Висновки. Аналіз структури модельних систем з використанням низьколактозної молочної сироватки і солей селену, конденсованих контактним способом, дозволив встановити раціональний вміст останніх в діапазоні 0.0087...0.0176 %, при якому спостерігається утворення однорідної дрібнодисперсної мікроструктури. Це дозволяє передбачати високі технологічні властивості, стабільність стуктури готових селен-білкових добавок при їх зберіганні і застосуванні.
ІЗОТЕРМІЧНИЙ ПЕРЕРІЗ ДІАГРАМИ СТАНУ СИСТЕМИ ZrO2–HfO2–Sm2O3 ПРИ 1600 C
Authors: В. Юрченко Юрій , Корнієнко Оксана А. , І. Биков Олександр , Самелюк Анатолій В.
Published: June 2022

За результатами зразків досліджених методом рентгенофазового та мікроструктурного аналізів досліджено фазові рівноваги в потрійній системі ZrO2–HfO2–Sm2O3. Утворення нових фаз у системі ZrО2–HfO2–Sm2O3 при 1600 °С не спостерігалося. Встановлено, що в дослідженій системі при 1600 °С утворюються поля твердих розчинів на основі тетрагональної (Т) модифікації ZrО2, моноклинної (М) модифікацій HfO2 і моноклинної (В) модифікацій Sm2O3, а також упорядкованої фази зі структурою типу пірохлору (Ру) Ln2Zr2O7 (Ln2Hf2O7). Визначено границі фазових полів та параметри елементарних комірок утворених фаз. Досліджений ізотермічний переріз системи ZrО2–HfO2–Sm2O3 характеризується утворення неперервних рядів кубічних твердих розчинів на основі фази зі структурою типу пірохлору Sm2Zr2O7 (Sm2Hf2O7) та зі структурою типу флюориту F-ZrO2 (HfO2). Встановлено, що в дослідженій системі утворюється дві області гомогенності кубічних твердих розчинів зі структурою типу флюориту. Існування цих областей гомогенності обумовлено розривом розчинності фази F-ZrO2 (HfO2) в області існування упорядкованої фази зі структурою типу пірохлору Sm2Zr2O7 (Sm2Hf2O7). Встановлено, що твердий розчин на основі кубічної модифікації зі структурою типу флюориту існує в рівновазі з усіма фазами, що спостерігаються в системі. Ізотермічний переріз дослідженої діаграми стану системи ZrO2–HfO2–Sm2O3 при 1600 °С характеризується наявністю однієї трифазної (F+T+M), а також п’яти двофазних (B+F, дві – F+Py, M+F, T+F) областей.
ДОСЛІДЖЕННЯ ЗМІНЕННЯ ВЛАСТИВОСТЕЙ КРОХМАЛЮ В ПРОЦЕСІ ОКИСНЕННЯ ПРИ СТВОРЕННІ КОМПОНЕНТУ КЛЕЙОВОГО МАТЕРІАЛУ ДЛЯ ПОВЕРХНЕВОГО ПРОКЛЕЮВАННЯ ПАПЕРУ
Authors: Шаріпов Музаффар С.
Published: June 2022

Метою даної роботи є вивчення впливу процесу окиснювальної модифікації на властивості кукурудзяного крохмалю з метою його використання в якості клею для поверхневого проклеювання паперів у процесі виробництва гофрованого картону. В основі технології окиснення крохмалю лежить процес обробки крохмальної суспензії або дисперсії окиснювальними реагентами, наприклад, перекисом водню. У статті наведено результати вивчення властивостей кукурудзяного крохмалю у процесі окиснення гідроген пероксидом у присутності FeSO4. Встановлено, що збільшення концентрації сухих речовин у дисперсіях окисненого крохмалю призводить до зростання міцності драглів. При цьому рівноважна вологість окисненого кукурудзяного крохмалю має значення дещо нижче, аніж зразки нативного крохмалю. Одержані дані дають можливість використовувати окиснені крохмалі для приготування на їх основі клейових матеріалів для використання у виробництві паперу та картону.
КВАНТОВО-ХІМІЧНЕ МОДЕЛЮВАННЯ АЦИДОХЛОРОКОМПЛЕКСІВ Cu2+, ЩО МІСТЯТЬ АНІОНИ ОРГАНІЧНИХ КИСЛОТ
Authors: Варгалюк Віктор Ф. , Полонський Володимир А. , Курасова Юлія Д.
Published: June 2022

Розглядаються результати квантово-хімічного моделювання (Gaussian 09, функціонал B3LYP) комплексних структур, які можуть утворюватися з аквакомплексів Cu2+, хлорид-іонів та аніонів органічних кислот (малонова, бурштинова, малеїнова, фумарова, мурашина, оцтова, пропіонова, бутанова, акрилова). Показано, що досліджуваний ряд органічних кислот утворює дві лінійні кореляційні залежності pК монозаміщених ацидоаквакомплексів Cu2+ від ефективного заряду центрального атома. Одна відноситься до аніонів одноосновних кислот, інша – до аніонів двоосновних кислот. Використання параметрів відповідної pК, z*(Cu2+)-залежності та результатів розрахунку z*(Cu2+) дозволило визначити значення pК для акрилатних комплексів Cu2+, що дорівнює 1.778, відомості про яку у літературі відсутні. За ступенем зміни ефективного заряду іонів Cu2+ у комплексах [Cu2+(L)] оцінено електронодонорність лігандів: аніони органічних кислот (−51.95 %) > Cl− (−47.75 %) > H2O (−21.45 %). Однак, у полілігандних аквакомплексах, за рахунок утворення гідрату L · H2O, аніони органічних кислот поступаються хлорид-іонам. При введенні аніонів хлору у внутрішню координаційну сферу монозаміщених аніонами органічних кислот аквакомплексу Cu2+ спостерігається закономірне послаблення зв'язків Cu2+–L. Ступінь зменшення Eb(Cu2+-L) залежить від природи органічної кислоти. Для насичених структур ΔEb знаходиться в інтервалі 2–8 кДж/моль, для ненасичених досягає 20 кДж/моль. Синхронно змінюється і енергетика реакції заміщення молекул води в ацидоаквакомплексі Cu2+ аніонами хлору (з −4 до −30 кДж/моль). Це, а так само те, що енергетичний ефект реакції приєднання Cl− до ацидоаквакомплексів Cu2+ з ненасиченими аніонами є ще більшим, досягаючи −62 кДж/моль у присутності фумарат-іонів, створює сприятливі початкові умови для синтезу змішаних ацидохлорокомплексів Cu2+, які містять аніони ненасиченних кислот. У розчинах насичених кислот очікується утворення тільки комплексів виду [Cu2+(H2O)4(Cl)] та [Cu2+(H2O)4(L)].
“Valle Alto”: Una lectura desde la corporalidad telúrica y el erotismo
Authors: Acuña Jiménez Karen , Garita Matamoros Mayte
Published: June 2022

El cuento “Valle alto” de la escritora costarricense Yolanda Oreamuno (1916-1956) se enmarca en la primera mitad del siglo XX y se corresponde con las manifestaciones artísticas contestatarias contra las imposiciones normativas patriarcales de la época. En este artículo, se propone que los constructos sociales establecen lo permitido y lo censurado en cuanto a la conducta femenina, su sexualidad y su deseo y que impactan no solo en su conducta, sino también en sus pensamientos. Por consiguiente, se plantea una disputa entre un espacio que remite a lo debido, el cual se manifiesta a partir de las acciones de la protagonista, en su intento de controlar sus fantasías eróticas ante la figura masculina, y lo deseado. No obstante, mediante la interacción de la naturaleza con la corporalidad femenina, la normativa deja de regir y le permite al instinto tomar el control. Como tal, se configura una liberación erótica, sensitiva y normativa.
New Insights into Debussy's Sketches for the String Quartet Op. 10
Authors: Delécluse François
Published: June 2022

This article provides new perspectives on Claude Debussy's compositional process in his String Quartet through a fresh examination of existing sources, particularly a sketchbook kept in the Bibliothèque nationale de France. First, the fragmentary nature of the material contained in the sketchbook implies the existence of another manuscript, now lost. By analyzing Debussy's notations for his String Quartet in greater detail, it is possible to question the different functions the latter took on in the compositional process: in addition to the musical ideas simply noted as an aide-memoire, there are more exploratory musical fragments. Furthermore, the description and analysis of the sources of the String Quartet's creative process enhance our knowledge of Debussy's compositional methods and techniques. These new insights into the sources also show how Debussy adapted to certain social and aesthetic constraints when writing the String Quartet. The compositional context, the very genre of the quartet, and the fact that Debussy was close to Chausson and the Société nationale, led him to seek compositional solutions to combine the techniques of the Franck school with the personal aesthetic he was developing at the time. In particular, the article reconstructs part of the composer's reflection on the cyclic design, which is at the heart of the questions raised in the sketches.
Adoption and Transformation of Traditional Forms in the Fourth String Quartet of Béla Bartók
Authors: Borio Gianmario
Published: June 2022

In describing the form of his Fourth String Quartet, Bartók employed the terminology of the German Formenlehre with which he was acquainted thanks to the teaching of Hans Koessler. Bartók's elucidation suggests that the models for the construction of thematic units, contrasts, developments and closing segments, which were normative for the sonata cycle in the nineteenth century, continued to exercise their influence despite the distance from functional tonality. An analysis of the five movements of the Fourth String Quartet with systematic reference to Bartók's synopsis shows that a subtle dialectic between adoption and transformation was at stake. The principles of traditional form gained new strength through the reinvention of harmonic structures, melodic lines and hypermetric groups. The symmetrical–architectural framework was preserved but filled with unconventional tone progressions, irregular phraseology, and a new sense for development and reprise.
Prenatal genetic diagnosis of retinoblastoma in two Vietnamese families
Authors: Minh Chau Pham Thi , Hong Anh Trinh , Lan Anh Luong Thi , Thuy Duong Nguyen , Hai Ha Nguyen
Published: June 2022

Retinoblastoma (Rb) is a rare cancer that develops from the layer of cells in the retina. A germline mutation in the RB1 gene is a high risk factor for Rb. We performed prenatal genetic diagnosis on two pregnant women who had had a child with hereditary Rb and continued checking their newborns' conditions after giving birth. Ultrasound-guided amniocentesis, amniotic cell culture, and Sanger sequencing for the specific RB1 region were used. The analysis results demonstrated that one of the amniotic cell samples was found to carry a genetic mutation that causes the disease, inherited from the father. Neonatal screening confirmed that the corresponding newborn of the amniotic cell sample with the causative gene mutation developed binocular retinoblastoma. Prenatal genetic testing on pregnant women in families with a risk of having a child with retinoblastoma should be performed to prepare a clinical diagnosis and treatment plan for the neonate.
QUAL É A INFLUÊNCIA DA MICROBIOTA NA OBESIDADE E EM SEU QUADRO INFLAMATÓRIO?
Authors: Machado Thiago , Dias Gabriella Micheten , Sigwalt Marcos Fabiano , Nassif Paulo Afonso Nunes , Tabushi Fernando Issamu
Published: June 2022

A obesidade tem causa multifatorial que atinge atualmente mais da metade da população brasileira. Mais recentemente, a microbiota intestinal foi considerada um fator que contribui para essa condição. Os objetivos deste estudo foram revisar a influência da microbiota intestinal na obesidade e no processo inflamatório, e analisar os efeitos da utilização dos pré e probióticos. Foi realizada revisão sistemática sobre o assunto. Dos mais de 27.000 artigos, apenas 16 respeitaram os critérios de inclusão. Em conclusão, o desequilíbrio da microbiota aparece como fator favorável ao desenvolvimento da obesidade e do quadro inflamatório decorrente dela. Tanto o uso de prebióticos quanto probióticos são recursos válidos no tratamento da obesidade, porém os primeiros parecem proporcionar melhor qualidade de vida.
Impact of Imputation Strategies on Fairness in Machine Learning
Authors: Caton Simon , Malisetty Saiteja , Haas Christian
Published: June 2022

Research on Fairness and Bias Mitigation in Machine Learning often uses a set of reference datasets for the design and evaluation of novel approaches or definitions. While these datasets are well structured and useful for the comparison of various approaches, they do not reflect that datasets commonly used in real-world applications can have missing values. When such missing values are encountered, the use of imputation strategies is commonplace. However, as imputation strategies potentially alter the distribution of data they can also affect the performance, and potentially the fairness, of the resulting predictions, a topic not yet well understood in the fairness literature. In this article, we investigate the impact of different imputation strategies on classical performance and fairness in classification settings. We find that the selected imputation strategy, along with other factors including the type of classification algorithm, can significantly affect performance and fairness outcomes. The results of our experiments indicate that the choice of imputation strategy is an important factor when considering fairness in Machine Learning. We also provide some insights and guidance for researchers to help navigate imputation approaches for fairness.
The Sobieski family and their properties in Royal Prussia
Authors: Karyś Jerzy Witold
Published: June 2022

In Royal Prussia, on the tern of XVII century, the economy system exist as: villain, compound and based on the rent. In Vistula Żuławy, it was profiting with fertile soil and irrigated fields and with the modern method of forming. That system was permitting become rich. Big sense was work of menonits, residing in northern regions and first of all in the Nowy Dwór economy. King Jan the third Sobieski obtained economy success but his sons first of all defeats cased by the third northern war. New Polish king August the second was combating with Sobieski family. These was the cause that Sobieski family successively was selling the properties in the Royal Prussia – in 1717 year and 1720 year. In 1733 year in Poland was beginning itself succession war, which wasn’t advantageous for the last property of Sobieski family in spite of some written interventions of Jakub Ludwik. After a longtime, in 1743 year the presence of the Sobieski family in Royal Prussia was ended.
Reforms in Spain (1782–1792) in the light of the reports of the „Historical and Political Diary”
Authors: Stroynowski Andrzej
Published: June 2022

The journal of priest Piotr Świtkowski played an important role in shaping the political awareness of Poles in the years 1782–1792. A particular merit of this journal was providing extensive knowledge about the political, economic and social situation, and mainly about the Enlightenment reforms in Europe. Spain was also among the countries discussed by Father Świtkowski. He treated it as a country at a similar level of development to Poland. This was to inspire Poland to undertake reforms similar to those implemented in Spain.
History of the Radom Squadron (November 1918 – March/April 1919 ). Contribution to the history of voluntary voivodeship squadrons of the Polish Army
Authors: Smoliński Aleksander
Published: June 2022

In the study, the Author presented the plans and the process of developing the cavalry of Polish military units- the Polish Army- in the period from November 1918 to the beginning of April 1919. In this context, he described the emergence and formation, and next the participation of the voluntary Radom Squadron, which was one of the voivodeship squadrons formed at that time in the former Kingdom of Poland, in the Polish Ukrainian war. Its history has been described until the moment of incorporation into the ranks of 11th Legions Uhlan Regiment.
„Under the flags of Homeland” at Napoleon’s side. Insurrection-al activity in Lelow County in 1806 in the light of report of the Lelow County Commission to the Administrative Chamber of Kalisz Department
Authors: Gorzałka Przemysław
Published: June 2022

The Greater Poland Uprising of 1806 is one of the few Polish military insurrections ended in victory. It started in November 1806 during the war between Napoleonic France and the Kingdom of Prussia. The uprising started in Poznań Department with support of the Grande Armée and than it spread over the Kalisz Department. After the brilliant conquest of the fortress of Częstochowa, made by Polish insurgents and French chasseurs, the insurrection reached New Silesia, a small part of the former Kraków Voivodeship. The nobles of Lelów County signed an act of uprising and established Lelów County Provisional Commission to take control over the region. They removed old Prussian authorities, symbols and, what is the most important, they started to organise Polish troops. Eventually, their efforts helped to bring into existence the Duchy of Warsaw.
Scientific conference The Fate of Poles after September 17, 1939 in the eastern provinces of the Second Polish Republic, Częstochowa February 8, 2020
Authors: Liwoch Sebastian
Published: June 2022

On February 8, 2020, a scientific conference was held in Częstochowa, organized jointly by the For Countryman Foundation and the Institute of Remembrance and Borderland Heritage based in Lublin. The meeting was preceded by a collection of charitable gifts for the Polish diaspora from the east. The patronage over the conference and the action was taken by a World War II veteran, Lt. Col. Antoni Łapiński and a Member of the Polish Parliament, Grzegorz Braun. The main theme concerned the broadly understood history of the Eastern Borderlands of the Second Polish Republic. The deliberations took place in Częstochowa, and six researchers representing various research centers took part in them. Extended versions of the papers with additional texts were published a few months later.
A relative clause analysis of event existential constructions in Aklanon
Authors: Wellstood Zachary
Published: June 2022

This study is the first to document and analyze the ‘event existential construction’ (EEC) in Aklanon (AKL), an understudied Central Philippine language. In EECs, the apparent correlation between Philippine-type voice and nominal case appears to break down. However, I argue that the ‘case-cleaving effect’ of EECs is superficial. I argue for an analysis wherein the existential maj selects a relative clause as its complement and allows optional possessor raising of a relative- clause-external agent, which obligatorily controls a DP-internal PRO, to topic position, producing the case-cleaving effect. This study presents a typologically unusual type of obligatory DP control and contributes to a richer understanding of cross-linguistic variation in Philippine languages, while allowing us to maintain the robust generalization that Philippine-type voice is correlated with the argument role of the topic-marked nominal.
Generating a low-copy overexpression cell line using PhiC31 integration v1
Authors: Tomic Goran
Published: June 2022

This is an in-house adaptation of the commerically available Jump-In system by Thermo. It generates clones with a lower overexpression level than those generated by lentivirial delivery and can be carried out in a standard CL1 tissue culture room. The gene of interest in the attB construct is assembled in-house and is driven by the PGK promoter and contains the BGH pA sequence (assembled from pX28 plasmid (Addgene Plasmid #46850), which had the required sequences). pCMVInt plasmid that expresses the PhiC31 integrase was purchased from Addgene (Plasmid #18935). This protocol is made combining the protocol for Jump-In system (ThermoFisher) and phiC31 Integrase Vector System (System Biosciences).
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Authors: not provided balvindua
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Authors: A H
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Nano-CUT&Tag for multimodal profiling of the chromatin v1
Authors: Bartosovic Marek
Published: June 2022

Nano-CUT&Tag is a multimodal technology to profile several histone modifications at the same with single-cell resolution. Nano-CUT&Tag implements a novel Tn5 fusion proteins to anti-mouse and anti-rabbit secondary nanobodies. Optionally, ATAC-seq can be performed prior on the same sample to profile open chromatin at the same time. Novel tagmentation protocol, which involves two-step tagmentation by MeA and MeB oligonucleotides yields increased number of fragments per cell comparing to previous single-cell CUT&Tag protocols on 10x Genomics platform.
[RETRACTED] Real Body Keto ACV Gummies: Reviews, Side Effect, Cost and Where To Buy! v1
Authors: not provided bestproducts
Published: June 2022

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Authors: CBD Gummies PureVera
Published: June 2022

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Chloramphenicol 25 mg/mL Stock Solution v1
Authors: Clark Bailey
Published: June 2022

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Authors: not provided wakashikalopar
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Authors: not provided termaposetion
Published: June 2022

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Nucleofection and single-cell cloning of CRISPR KO clones v1
Authors: Tomic Goran
Published: June 2022

This protocol describes the process of nucleofection of sgRNA in PX458 plasmid into a mouse cancer cell line and subsequent flow sorting of single cells based on GFP fluorescence.
Presence of nitrates and nitrites in fresh cow milk from milk machines during winter and summer period in the city Zagreb and Zagreb County area
Authors: Brkić Martina , Bošnir Jasna , Brkić Danijel , Bevardi Martina , Racz Aleksandar , Lasić Dario , Đido Vedran , Pašalić Arzija , Vlainić Marko
Published: June 2022

Introduction: The aim of the study was to determine the nitrites and nitrates content in fresh cow’s milk samples from milking machines, and to determine whether their amount is affected by the season of sampling (summer/winter).
Methods: The methodology used was analytical transversal method at 2-time points. All milk samples were sampled at milk machines from the City of Zagreb and Zagreb County, during the summer and winter months in 2020. A total of 40 milk samples were sampled, with 20 samples in each monitored period (summer/winter). A high-performance liquid chromatography with a diode array detector was used to identify and quantify concentrations of the nitrate and the nitrite content. The results were processed using descriptive statistics and the statistics of differences.
Results: The analysis determined the range of nitrate content from 1.28 mg/kg to 19.71 mg/kg and the range of nitrite content was from 0.49 mg/kg to 3.42 mg/kg in milk samples. The mean result of nitrates in fresh cow’s milk samples in the summer period was 9.12 mg/kg and in the winter period of 3.88 mg/kg. The mean value of nitrite in the summer was 1.23 mg/kg, while the mean value of nitrite in the winter period was 1.48 mg/kg.
Conclusion: The research has shown that the nitrate and the nitrite levels in local fresh cow’s milk sampled in milk machines do not exceed the maximum allowable intake. The obtained results confirmed that the amounts of nitrates and nitrites in the milk samples differ significantly during the winter and summer periods and differences are depending on the location of the milk machine.
Procedural Cities as Active Simulators for Planning
Authors: Roumpani Flora
Published: June 2022

Modelling a 3D city poses an interesting challenge. To create a virtual city, a road pattern has to be designed and a large number of buildings need to be generated. Every urban place has a road network, often a superimposed pattern plan that serves a population density and buildings which follow statutory rules. This patterned behaviour of the city is why it is possible to develop rules or “computational instructions,” to generate city models. In this article, we are going to discuss how to use procedural modelling and CityEngine, a rule-based application commonly used in the movie industry and gaming to produce vast realistic cityscapes, for regional and urban planning via an urban analytics approach. Unlike cinema’s imaginary worlds, cities have real-life population dependencies that need to be modelled for the development of planning scenarios. The goal is then to use the generative properties of the procedural modelling approach, along with population prediction models, to create informed 3D city scenarios. Instead of designing solutions, the user can use interactive parameters to affect the 3D model globally, thus enabling virtual cities to become active simulators for planning. Using urban analytics and generative environments, procedural cities may be able to create a “teaser” of different versions of how the city would look like in the future.
THE IMPACT OF THE COVID-19 PANDEMIC ON DAIRY PRODUCTION IN RUSSIA
Authors: Semenova А. М.
Published: June 2022

The dairy industry is one of the most important among the food industries of the national economy. The industry includes enterprises for the production of animal oil, whole milk products, dairy preserves, milk powder, cheese, brynza, ice cream, casein and other dairy products. The article analyses the self-sufficiency of the Russian Federation with milk and dairy products in 2016-2020 and the period of the COVID-19 pandemic. The analysis of import and export of dairy products based on FCS data is also given.
ANALYSIS OF GEOTRAKING SYSTEMS AS AN EFFECTIVE TOOL FOR MONITORING FIELD PERSONNEL IN BTL AND MARKETING RESEARCH
Authors: Kalin L. S. , Kerzina E. A.
Published: June 2022

In this scientific work, an analysis of geotreking systems was carried out. Companies that develop and distribute these systems, companies that use their services were identified and considered. The scale of all activities, a comparative analysis of development companies, and an analysis of the effectiveness of these products were analyzed.
THE MAIN DIRECTIONS OF INNOVATION IN TRANSPORT
Authors: Tyshtykova S. I.
Published: June 2022

This article highlights the main problems in the transport industry that hinder the development and implementation of innovations in this area. The description of the innovative infrastructure is given, which is able to ensure the implementation of innovative projects in the context of the main innovative directions in transport. The main innovative directions in transport that contribute to the development of the transport system of Russia are considered.
ONLINE KIYAFET MAĞAZALARINDA ELEKTRONİK HİZMET KALİTESİ, SADAKAT VE AĞIZDAN AĞIZA İLETİŞİM TÜRLERİ İLİŞKİSİ
Authors: Erdoğan Görkem
Published: June 2022

Bu çalışmada online kıyafet mağazalarındaki elektronik hizmet kalitesi, sadakat, sözlü ve elektronik olmak üzere ağızdan ağıza iletişim ilişkisini açıklayan model kurulacaktır. Online kıyafet alışverişi yapmış 313 kişinin anket sonuçlarına göre çalışmadaki ifadelerin kaç tane değişken oluşturacağını kapsayan keşfedici faktör analizi, kurulan hipotezleri test etmek için de doğrulayıcı faktör analizi ve yapısal eşitlik modeli kullanılmıştır. Elektronik hizmet kalitesinin sadakati pozitif yönde etkilediği diğer taraftan sözlü ağızdan ağıza iletişimin şiddetini negatif yönde etkilediği sonucuna ulaşılmıştır. Ayrıca sadakatin tüm ağızdan ağıza değişkenlerini pozitif yönde etkilediği sonucuna varılmıştır.
El Bal Tik Tak de Giacomo Balla. Un proyecto de decoración futurista
Authors: Mancebo Roca Juan Agustín
Published: June 2022

El reciente descubrimiento y restauración de los murales que Giacomo Balla pintó en el Bal tic tac comisionado por Ugo Paladini en 1921 han recuperado el interés por el pintor y sus intervenciones futuristas sobre mobiliario y decoración derivadas de su manifiesto Ricostruzione futurista dell´universo. Este artículo reconstruye la intervención de Balla a partir de los escasos testimonios gráficos y bocetos para la ambientación del local romano. Asimismo, incide en la programática disolución entre las líneas de arte y vida basadas en las reseñas de su inauguración, el local y su música que convirtieron al Bal Tik Tak en uno de los locales emblemáticos de las mundanas noches romanas. Su éxito sirvió para la creación de otros espacios futuristas similares como el Cabaret del Diavolo en 1922 y el Cabaret della gallina a tre zampe en 1923 e influyó en otros espacios similares de la vanguardia europea.
Sumario
Authors: Rodríguez-Muñiz Luis J.
Published: June 2022

Sin resumen
Estrategias, sesgos y dificultades en un proceso de coaching grupal de líderes escolares
Authors: López-Yáñez Julián , Sánchez-Moreno Marita
Published: June 2022

Este artículo analiza los procesos de reflexión grupal en un programa formativo para directores/as escolares y, más concretamente, los sesgos y dificultades relacionados con: las condiciones estructurales relativas a la composición y dinámica de los grupos; las dificultades para reunir información relevante; los sesgos en el procesamiento de la información;y los sesgos que impidieron lograr una reflexión profunda. El marco teórico se apoya en la idea de reflexividad y en la literatura que ha analizado los procesos de reflexión grupal, específicamente los relacionados con el análisis de la propia experiencia de los participantes mediante estrategias basadas en el feedback entre pares y el coaching grupal. Los datos, procedentes de una investigación financiada que pilotó el programa formativo, fueron analizados mediante una versión adaptada del instrumento de Schippers et al. (2014).  Se seleccionaron dos grupos de directivos que obtuvieron resultados muy dispares en el logro de los objetivos del programa. El sistema de análisis de la reflexión grupal reveló que la diferencia entre ambos grupos se debía principalmente a su capacidad para superar las dificultades comunicativas mediante estrategias apropiadas. Los resultados también revelaron la utilidad del instrumento de análisis para orientar la formación que requieren los facilitadores de la reflexión grupal.