bluuebunny/crossref_metadata_2025 huggingface dataset:
EFEITOS DA HOSPITALIZAÇÃO SOBRE A FADIGA, QUALIDADE DE VIDA, ENFRENTAMENTO, FLEXIBILIDADE, FORÇA DE PREENSÃO MANUAL DE CRIANÇAS COM CÂNCER: SÉRIE DE CASOS
Authors: Rafael Aline Dandara , De Macedo Ana Carolina Brandt , Neves Valéria Cabral
Published: July 2022

Introdução: a criança com câncer, quando hospitalizada, frequentemente é submetida a tratamentos estressantes e com altos índices de morbimortalidade. Estudos que avaliam a condição física dessa população, durante o seu tratamento são importantes. Objetivo: descrever os efeitos da internação hospitalar sobre a fadiga, qualidade de vida, flexibilidade e força de preensão manual de crianças com câncer. Métodos: estudo descritivo em formato de série de casos, no qual foram avaliadas quatro crianças, idades entre 8 e 15 anos, para as variáveis sociodemográficas, fadiga, qualidade de vida e capacidade de enfrentamento hospitalar pelos questionários PedsQL-Multidimensional Fatigue Scale, PedsQL-Pediatric Quality of Life Inventory Generic-3.0, PedsQL-Module Cancer. A flexibilidade foi avaliada com o teste sentar e alcançar; e a força de preensão manual, pelo dinamômetro Jamar®. Resultados: as crianças hospitalizadas tiveram média no tempo de diagnóstico de 9,7±6 meses. O tempo de internação foi de 12,2±6,8 dias. Durante a hospitalização houve decréscimo nos índices de qualidade de vida e aumento da fadiga. As forças de preensão manual e flexibilidade se mantiveram em três dos quatros participantes. Conclusão: as crianças com câncer avaliadas sofreram algum efeito da hospitalização, afastam-se do seu maior convívio social, que é a escola, têm receio de sentir dor e não praticam atividade física. O participante com maior tempo de diagnóstico e maior período de internamento apresentou fadiga, fadiga no sono, menor qualidade de vida, maior dificuldade para enfrentar a doença. A menor flexibilidade foi verificada em dois pacientes. Duas crianças tiveram diminuição na força de preensão manual.
“THE MORE I LIVE, THE LESS I UNDERSTAND WHAT’S GOING ON”
Authors: Polyarinov Alexey , E.S. Maksimova
Published: July 2022

Alexey Polyarinov is a writer, finalist of the “Big Book” Award (2021) and the “NOS” Award (2021), author of the novels “Gravity centre”, “Reef”, co-translator (with Sergey Karpov) of the novel “Infinite Jest” by David Foster Wallace. In the issue of P&I, dedicated to fragmentation, Alexey Polyarinov talks about Wallace, Pynchon, Updike, Remark, “Man from Podolsk”, “Parasites”, regeneration, and the last album of Oxymiron. Interview by Ekaterina Maksimova. Photo by Valya Goltsberg.
An Iron(III)-S-methylthiosemicarbazone Complex: Synthesis, Spectral Characterization, and Antioxidant Potency Measured by CUPRAC and DPPH Methods
Authors: KAYA Büşra
Published: July 2022

An iron(III) complex, [Fe(L1)Cl].H2O, was synthesized by template condensation reaction of 1,1,1-Trifluoroacetylacetone-S-methylthiosemicarbazone hydrogen iodide (L) and 2,3-dihydroxybenzaldehyde in the presence of iron(III) ions. The complex was characterized by IR, ESI MS and X-ray diffraction techniques. Free radical scavenging (FRS) ability and antioxidant capacity of the S-methylthiosemicarbazone and the iron(III) complex were evaluated through DPPH and CUPRAC methods, respectively. The complex exerted better than the S-methylthiosemicarbazone in both TEAC and FRS% values. In addition, iron(III) complex was found to be 3.1 times more antioxidant than the reference ascorbic acid according to the CUPRAC method.
Salicylaldehydediol Grafted onto Chitosan: Characterization and Their Film Properties
Authors: EVCİL Murat , KARAKAPLAN Mehmet
Published: July 2022

The concentrations of linker group effect different physicochemical features of the biopolymer, including thermal stability, shape, swelling, and water solubility. Herein, three novel chitosan (CH) based films (CHSD1-3) have been prepared by a facile method for their film characteristics. Thus, amphiphilic salicylaldehydediol (SD) was synthesized from hydrophilic glycidol and salicylaldehyde in high yield and regioselectivity. CHSD1-3 films were prepared by the imine condensation reaction of polymeric chitosan backbone and various ratios of SD linker. The reaction takes place with high conversation and amazingly mechanically resistant thickness films without using any plasticizer that exhibits low water solubility and low swelling ratios at pH > 3, which can be suggested as thin layer protecting systems for medical devices. Chitosan-salicylaldehydediol biopolymer films were characterized by Fourier transform infrared (FT-IR) spectroscopy, differential scanning calorimetry (DSC), and X-ray diffraction (XRD) methods. The FT-IR, DSC, and XRD results show a clear linkage of the SD group to the chitosan backbone, high thermal stability of the films, and a change in the original nature of chitosan, respectively. Scanning Electron Microscopy (SEM) observations have also supported the successful grafting of the SD group onto the chitosan.
Breeding of parthenocarpic cucumber hybrids for unheated greenhouses
Authors: Chistjakova L. A. , Baklanova O. V.
Published: July 2022

Relevance. Cucumber is very popular and in demand in households of the population (personal subsidiary farms), as evidenced by the data on the acreage occupied under this crop in the territory of the Russian Federation (37.4 thousand hectares).

Methodology. This article presents the results of evaluating the combinational ability of eight parthenocarpic inbreeding lines and testing thirteen new hybrid combinations obtained on the basis of the studied lines under the conditions of spring-summer turnover in a polycarbonate unheated greenhouse in the Moscow region in comparison with the hybrids F1 SV 4097 CV (Seminis, the Netherlands) and F1 Piligrim (Agrofirma Poisk LLC, Russia).

The purpose of the scientific work is to develop productive and high-yielding heterotic cucumber hybrids with a complex of economically useful traits for cultivation in unheated greenhouses. Testing and introduction of competitive and technologically advanced hybrids into commercial vegetable production is one of the important stages of scientific research in the field of breeding. The research was carried out in ARRIVG – a branch of FSBSI “Federal Scientific Vegeculture Center” in the conditions of polycarbonate unheated ground greenhouses during 2020-2021 (Moscow region, Ramensky district).

Results. As a result of evaluation of the combinational ability of parthenocarpic inbreeding lines, it was found that inbreeding lines L.21 (2.4 kg/m2 ), L.415 (0.8 kg/m2 ), L.993 (0.4 kg/m2 ), L.1010 (0.1 kg/m2 ) should be used during hybridization as a paternal component for obtaining early-ripening parthenocarpic cucumber hybrids. To develop more productive and high-yielding parthenocarpic cucumber hybrids, inbreeding lines L.21, L.415, L.1008 should be used. As a result of the research work, four hybrid combinations (L.993×L.415, L.1010×L.21, L.993×L.21, L.993×L.1008) were identified for high yield and productivity in protected soil conditions, which exceeded the standards of SV 4097 CV F1 and Piligrim F1.
Ecological testing of Volgograd and Krasnodar variety of watermelon breeding in different zones of the south of Russia
Authors: Lazko V. E. , Varivoda E. A. , Yakimova O. V. , Kovaleva E. V. , Bocherova I. N. , Kovalev R. K.
Published: July 2022

Relevance. In order to form a targeted assortment of watermelon for specific soil and climatic conditions, an assessment was made and the results of the ecological adaptability of varieties bred by FSBSI “FNTs Rice” and Bykovskaya BSOS in different zones of melon growing were obtained.

Methodology. The object of the study is watermelon varieties bred by two research institutions. Tests were carried out in three agroecological zones: Astrakhan, Volgograd regions and Krasnodar region. Agrotechnical measures were applied in accordance with the recommendations adopted for the study area.

Results. Despite different soil and climatic conditions of cultivation, all varieties showed high potential yield, regularity and stability of fruiting, controlled by the genotype of the varieties. Varieties of watermelon are able to form a high yield in dry areas. Meteorological conditions during the growing period influenced the length of the growing season. From germination to ripening, the varieties of the early ripeness group showed an increase of up to 5...15 days, in the group of varieties of medium and late ripening up to 20...49 days. The spread in the limits of biometric indicators and fruit weight depended on weather conditions, but was within the varietal parameters. The factor of growing conditions did not influence the accumulation of dry soluble substances in the fruit pulp. Marketability of harvested fruits is 80…90% with high taste qualities. The results of the tests have shown that the varieties of the Krasnodar and Volgograd breeding show adaptability to the specific conditions of the region. Using them will make it possible to minimize losses from the weather conditions of the growing season and obtain stable and high yields.
Evaluation of the degree of dominance and heterosis effect of table watermelon according to the main economic characteristics
Authors: Varivoda E. A. , Varivoda G. V. , Verbitskaya O. G.
Published: July 2022

. Heterotic selection is now widely used in crop production. The superiority of heterotic hybrids over varieties in many respects has long been known. However, the widespread use of heterosis in melon growing is hampered by the high cost of seed material, due to the lack of lines with male sterility. The aim of this work was to evaluate heterotic hybrids of watermelon obtained on the basis of a line with male sterility isolated at the Bykovskaya Experimental Station.

Materials and methods. The studies were carried out in 2020 and 2021. at the Bykovskaya melon breeding experimental station - a branch of the FGBNU FNTSO. The object of research is heterosis hybrids of watermelon. The heterosis hybrid of watermelon Barkhan was used as a standard. Classical breeding methods were used in the work: incubation and hybridization.

Research results. The assessment of watermelon hybrids according to the main economic characteristics revealed the best combinations in comparison with the standard. According to the content of dry matter, four hybrids of watermelon stood out, the excess over the standard ranged from 0.6 to 1.9%. The indicator of the average weight of the fetus in one LIR hybrid was at the level of the standard and amounted to 6.5 kg. The remaining hybrids exceeded the Barkhan standard by 1.2-4.0 kg. The average yield of the studied hybrids ranged from 19.0 to 22.5 t/ha. The calculation of such indicators as the degree of dominance, the effects of true and hypothetical heterosis made it possible to identify three combinations with high rates.

Conclusion. Thus, it was found that the yield in heterotic hybrids of watermelon is inherited according to the principle of overdominance. Inheritance of traits dry matter content and average fruit weight ranges from minus overdominance to overdominance in various combinations. According to the complex of economically valuable traits, three combinations of table watermelon were distinguished: LKn, LMr and LFT.
Melon breeding for disease resistance in the Republic of Uzbekistan
Authors: Khakimov R. A. , Khalimova M. U.
Published: July 2022

Melon (Cucumis melo L.) is the most spread melon crop in Uzbekistan. More than 130 local varieties of melon are cultivated in various regions of the republic. Every year melons and gourds are cultivated on the area of 150 thousand hectares. The most harmful diseases of the melon are powdery mildew and Fusarium wilt. All local varieties of melon are susceptible to these diseases. Annually from these diseases, the yield of melon is reduced by 20-25%. The most effective way to combat these diseases is to develop resistant varieties. The Research Institute of Vegetable, Melon Crops and Potato has carried out long-term selection work to create melon varieties resistant to powdery mildew and Fusarium wilt. Breeding local varieties of melon with economically valuable traits and high test quality with genes for resistance to these diseases have been created and included in the State Register of Uzbekistan.
The automated cell counter for the analysis of morphological characteristics and the quantitative estimation of starch granules in different potato varieties
Authors: Volkov D. I. , Sobko O. A. , Fisenko P. V. , Matsishina N. V. , Gisyuk A. A. , Kim I. V. , Ermak M. A.
Published: July 2022

Relevance. Potato starch is widely used in the food, textile, perfume and pharmaceutical industries. The starch content and the size of starch granules in potato tubers are varietal characteristics (Solanum tuberosum L.). The knowledge of morphological properties of starch plays a key role in the technologies for the production of consumer and industrial goods.

Materials and methods. The studies were carried out in 2020-2021 at the experimental base of Federal State Budget Scientific Institution “Federal Scientific Center of Agricultural Bio-technology of the Far East named after A.K. Chaiki” (Primorsky Krai). The object of the research were 11 varieties of different maturity dates. Morphological structure of starch granules was evaluated by image analysis on Countess II FL automated cell counter.

Results. The varieties studied had predominantly rounded and oval pellets regardless of maturity and genetic origin. Differences in starch granule size depending on tuber size and ripeness group were noted. Early maturing varieties had granule size less than 20 microns regardless of tuber fraction. The exception is the variety Queen Anne, in small tubers of this variety starch granules larger than 20 microns is 67.86%. It was noted that the proportion of medium and large grains increased in varieties with a longer growing season. For example, the variety Augustin medium-ripening had a proportion of medium and large grains in the large and small tuber of 47.72 and 41.48%, respectively. The maximum number of grains larger than 20 microns was observed in the mid-late varieties Kazachok (63.77%) and Smak (92.22%).

Conclusion. The method using a cell counter and subsequent processing of microphotographs of starch granules is an accessible, economical, simple and effective approach to phenotyping potato varieties and hybrids of Solanum tuberosum L. by physical and chemical parameters of starch. This method can be used for accelerated analysis of a large number of samples on a limited amount of natural material, including in field and farm laboratories.
Biological features of the development of early potato varieties in the Murmansk region
Authors: Zhigadlo T. E.
Published: July 2022

Potato (Solanum tuberosum L.) is a fairly popular agricultural crop in Russia, the tubers of which are the main food of the population. For the North, it is important to replenish the assortment of early potato varieties adapted to growing in extreme conditions. The aim of this research was to study the development of plants of early and mid-early potato varieties in the Murmansk region.

Methods. The article presents the results of studying the developmental biology and productivity elements of 63 early and mid-early varieties from the of VIR world potato collection. The Khibinskiy ranniy variety is used as a standard. The study was conducted on the territory of the Polar Experimental Station of Apatity. The soil of the experimental plot is sandy loam, highly cultivated, the organic matter content is 8,7%, pH 5,2; Р2О5 – 103 mg/100 g, К2О – 39,2 mg/100 g of soil. The total area of the plot was 286,5 m2 , the counting area was 5 m2, the planting scheme was 70x30 cm, the experiment was repeated three times, the distribution of varieties was randomized.

Results. Phenological observations revealed varieties with the shortest interphase periods: Ognivo, Sundinsky ranniy, Uralsky ranniy, Khibinskiy ranniy, Amazone, Aster, Lady Claire. Varieties Daryonka, Lyubava, Dolphin formed berries within three years.

Conclusion. Concorde, Corine и Karatop exceeded the standart at 50, 60, 75 days from planting in the years of study, which shows the ability of the cultivars for intensive tuberization in the early stages, combined with high stable productivity in the North. The significant influence of meteorological conditions on the development dynamics of potato plants, their yield and on the adaptive ability to local growing conditions has been identified. There singled out the cultivars that are characterized by consistently high rates of the dynamics of tuber accumulation in the early stages, possessing a high adaptive ability, which can be used in breeding for early maturity and productivity in the North regions.
Comparative evaluation of biochemical parameters and mineral composition of Cucurbita ficifolia, C. maxima and C. moschata fruit, grown in the northern hemisphere
Authors: Goncharov A. V. , Golubkina N. A. , Pivovarov V. F. , Gasparian I. N. , Caruso G.
Published: July 2022

Fruit peel/pulp distribution of biologically active compounds is an important characteristic of plant physiology and the basis of zero waste production in agriculture. Among C. ficifolia, C. maxima and C. moschata the former showed the lowest dry matter content, especially in peel, similar peel and pulp values of antioxidant activity (AOA) and polyphenol content (TP), with the highest levels in fruit placenta. Peel carbohydrate profile of C. ficifolia fruit was characterized by lower levels of disaccharides compared to C. maxima and C. moschata peel and an opposite pattern of monosaccharides accumulation. The analysis of 25 elements content in Cucurbita peel and pulp, using ICP-MS, indicated that C. ficifolia fruit are characterized by significantly high concentrations of Sr, Si and I in pulp compared to the values of C. maxima and C. moschata. On the contrary, C. maxima and C. moschata were characterized by low concentration of pulp Mn. Highly significant positive correlations were recorded between Cr-Sr, Cr-Ca and CaSr (r=0.906; 0.939 and 0.974 respectively) and P-Cu (r=0.968). Despite C. ficifolia, does not contain carotenoids, it is highly valuable due to the high levels of Si, I, Cr and Ca in peel and pulp, which reveals new areas of its application.
The main directions and tasks of pumpkin crop breeding of the FSBSI "Federal Scientific Vegetable Center»
Authors: Korottseva I. B.
Published: July 2022

Pumpkin crops are an important segment in the structure of cultivated vegetable crops. Their selection is mainly aimed at precocity, increased resistance to adverse climatic factors and the most harmful diseases (true and downy mildew, olive, angular and brown spots, anthracnose, viruses and other diseases). The article presents the main directions of selection work on cucumber, squash, zucchini and pumpkin in the FSBSI "Federal Scientific Vegetable Center". A network of branches of FSBSI "FSVC" engaged in the creation of new varieties, with specified parameters, for the above crops is presented. The features of breeding work on pumpkin crops in various regions of the Russian Federation are shown.
Increasing the yield of melon in a greenhouse at vegetative grafting on vegetable marrow rootstocks
Authors: Mavlyanova R. F. , Lyan E. E.
Published: July 2022

In Uzbekistan, there is a demand of the population for fresh melon fruits during the off-season. In the Research Institute of Vegetable, Melon Crops and Potato for the first time studies were carried out, when grown in a greenhouse, on the vegetative grafting of melon’s Zarkhal variety on the vegetable marrow varieties used as rootstocks. The aim of the research was to study the effect of vegetable marrow rootstocks on the variability of economically valuable traits of the Zarkhal melon variety and to identify promising combinations of vegetable marrow rootstocks that increase the yield and quality of melon fruits.

Methods. The studies were carried out in accordance with the guidelines of the World Vegetable Center. As a control, ungrafted plants of the Zarkhal melon variety were used. For comparison with the control, plants of this variety were grafted onto their own plants. Also, plants of the melon variety Zarkhal (scion) were grafted in combinations on 10 varieties of vegetable marrow, which served as rootstocks. Vegetative grafting of melon on vegetable marrow rootstocks was carried out “in a split” in the phase of the first true leaf when the stem diameter reached 4.1–4.3 mm and plant height 4.4–5.9 cm.

Results. In comparison with the control, in combinations of grafting the Zarkhal melon variety onto the Grecheskiye 110, Unumdor, Delicates and Skvorushka varieties of vegetable marrow, the flowering of paternal and female flowers, the onset of fruit formation was observed 2 days earlier. In the same combinations, fruit ripening was observed on 81-82 days, which is 4-5 days earlier than the control (86 days). They also had the tallest plants (203-205 cm), the plants formed 2-4 leaves more than the others. Marketable yields between combinations ranged from 7.89 to 9.75 kg/m2 . The melon variety Zarkhal, grafted onto its own plants, lagged behind the control in all phases of development and yield. The early yield in combinations was from 3.95 to 5.75 kg/m2 and amounted to 53-59% of the yield. The average fruit weight varied from 785 to 810 g.
Efficiency of the main application of fertilizers and top dressing of tomato under drip irrigation on ordinary chernozems of the Rostov region
Authors: Borisov V. A. , Sosnov V. S. , Menshikh A. M. , Vasyuchkov I. Yu.
Published: July 2022

Relevance. In modern vegetable growing in the southern and central regions of Russia, new scientific developments are widely used, including the use of new varieties and hybrids, a drip irrigation system, fertigation with soluble fertilizers with microelements. All these agricultural practices make it possible to increase the yield of vegetable crops by several times, as well as to significantly increase the efficiency of applied fertilizers. The purpose of our work was to establish the effectiveness of the use of calculated doses of mineral fertilizers for tomato with the main application and top dressing under drip irrigation.

Methodology. Research in 2019-2021 on ordinary heavy loamy chernozem of the experimental field of the Birutchecutskaya Vegetable Experimental Station – branch of FSBSI Federal Scientific Vegetable Center (Rostov Region, Novocherkassk) with a new variety of tomato Krasny banker.

Results. It was revealed that without fertilization, the yield of tomatoes was at the level of 32-35 t/ha; the use of the recommended dose of N120P120K120 in the main application increased the yield to 64- 72 t/ha; the use of the estimated dose of mineral fertilizers (for a yield of 100 t/ha) increased the yield of tomatoes to 95 t/ha. The use of three-fold root feeding of plants with drip irrigation increased the yield by 21%, and with foliar feeding – by 2-8%. As a root top dressing for drip irrigation, a solution of microcrystalline water-soluble fertilizer "Master" with a different ratio of nutrients was used, and for foliar top dressing, an organomineral nanofertilizer with growth-stimulating activity "Arksoil KKR" was used. In general, a set of agrochemical practices made it possible to increase the tomato yield under drip irrigation from 33.7 to 102.8 t/ha, more than 3 times, without reducing the dry matter content in fruits and without nitrate contamination of products.
Effect of sodium selenate foliar supplementation on Cryptotaenia japonica and Petroselinum crispum nutritional characteristics and seed quality
Authors: Kharchenko V. A. , Moldovan A. I. , Amagova Z. A. , Matsadze V. Kh. , Golubkina N. A. , Caruso G.
Published: July 2022

Production of functional food with high levels of selenium and other antioxidants is very valuable for human protection against different forms of oxidant stress. Among leafy vegetables parsley demonstrate the highest levels of antioxidants. Biochemical analysis and fluorimetric determination of selenium revealed that foliar biofortification of 4 parsley (Petroselinum crispum) cultivars and Mitsuba (Cryptotaenia japonica) with sodium selenate (25 mg L-1) resulted in the highest biofortification level in curly parsley cultivar Krasotka (102.9) which showed the highest leaf surface area, antioxidant activity (65 mg GAE g-1 d.w.) and flavonoids content (25.9 mg quercetin equivalent g-1 d.w.), and the increase by 1.4 times in carotene content and 1,5 times in total chlorophyll content. ICP-MS method of mineral composition evaluation recorded extremely high levels of B and Si in Mustuba, which increased due to Se supplementation by 1.23 and 1.46 times respectively. In a two-year experiment with control and Se-fortified, leafy parsley, cultivar Moskvichka reached high values of seed yield and viability, and seed Se content (6170 µg kg-1 d.w.). The results of the present investigation demonstrate high prospects of parsley and Mitsuba selenium biofortification for production of functional food with elevated levels of microelement and high antioxidant activity.
Research and creation of working organs of the tomato seed separator device
Authors: Gorobey V. P. , Moskalevich V. Y. , Pivovarov V. F. , Pavlov L. V.
Published: July 2022

Relevance. Seeds play an important role in obtaining a high yield of vegetable crops of good quality. Breeders usually deal with a large number of samples. To study the source material, the seeds of the samples are sown in boxes with soil for growing seedlings or in collection nurseries of experimental stations and research institutions. It takes an average of ½ hour of shift time to manually extract a sample weighing 10 kg from a batch. Currently, there are no sufficiently efficient devices for isolating tomato seeds from batches of samples with small weights up to 100 kg. The task of research on mechanization is to increase the efficiency of the tomato seed extraction device by improving the working bodies, determining the value of the optimal mass of samples, the extraction of seeds from which is economically and technically feasible.

Material and methodology. Experimental studies were conducted in order to find constructive solutions for working bodies, study their operability and determine optimal parameters and operating modes. The research program included: a study of the productivity of the layout and the complexity of its maintenance; a study of qualitative indicators, including seed loss, seed clogging, seed damage; a study of the modes of working bodies, including the number of revolutions of the whip shaft, gaps between the whips and the sieve, the angle of advance of the whips; an assessment of the convenience of cleaning and visual inspection of all surfaces of parts, in contact with seeds; analysis of the advantages and disadvantages of the design of mesh drums, scourges, mechanisms for locking semi-cylinders, the work of the fence that reclines together with the hopper.

Results. As a result of the research, it was found that drum-and-whip type working organs are economically feasible for use in tomato seed extraction devices with a sample weight of at least 100 kg (i.e. mainly in primary and elite seed production), due to the fact that the time for disassembly, cleaning and assembly of working organs is 95% of the cycle (for example for samples weighing 10 kg). The clogging of the seeds meets the requirements, crushing was not observed.
The influence of growth regulators on the ripening period, yield and quality of melon of the medium-ripened variety Osen
Authors: Ryabchikova N. B. , Kornilova M. S.
Published: July 2022

This article shows the influence of growth regulators and methods of their application on the passage of the main interphase periods and growth processes during melon cultivation. The use of growth regulators is one of the promising directions in the cultivation of melons. In the acutely arid areas of the Volgograd Volga region, the use of mineral fertilizers for melon crops, in bagar conditions, was not effective, since there was an acute shortage of moisture in the soil. Therefore, the most effective and promising for creating favorable conditions for the growth and development of melon plants, with the possibility of leveling negative environmental factors, is the use of foliar treatments in the cultivation technology with growth regulators. The studied drugs of the new generation have a wide range of physiological activity. They are designed to influence the parameters of growth and development of plants as a whole in various phases, as well as their organs, as well as the parameters of plant response to environmental factors.

Results. Studies have revealed the dependence of the growth processes of melon plants on the methods of using growth regulators, the length of the lashes in the variants of using growth regulators for processing plants during vegetation is longer compared to soaking seeds, with their maximum length in the Phytozont variant (plant treatment) is 12.7-51.3% longer compared to other studied preparations.
Influence of innovative plant growth regulators on physiological and biochemical parameters and yield of Solanum tuberosum
Authors: Verizhnikova A. A. , Prudnikova E. G.
Published: July 2022

Relevance. Solanum tuberosum L. – it is one of the main food crops, therefore, the study of the influence of innovative growth regulators on physiological and biochemical parameters and plant yield is very important for the agro-industrial complex.

Material and methods. The research was carried out on the gray forest soil of the Orel region in the conditions of a vegetation house on the basis of the farm Stebakov V.I. in the period 2020-2021. Potato of the Nevsky variety was used as the object of the study. Treatment with growth regulators was carried out by soaking Solanum tuberosum tubers in aqueous solutions of melafene (10-6%), Energy-M (10-3%) for 8 hours. When laying the experiments, the optimal amount of nitrogen (2.3 g), phosphorus (0.7 g) and potassium (3.1 g) was introduced into the soil for potato. Was determined catalase, peroxidase activity. The amount of hydroperoxides, an intermediate product of POL, was estimated by reaction with ammonium rhodanide, the content of malonic dialdehyde by reaction with thiobarbituric acid. The experiment was carried out three times. Statistical processing of the results was carried out by the method of one-factor analysis of variance using the computer program "MS Exel".

Results. Studies have shown that there is an increase in the activity of catalase and peroxidase in all variants of the experiment compared with the control in leaves, in tubers – the activity of enzymes decreases. There was a decrease in the content of malondialdehyde in all variants of the experiment compared with the control. The analysis of the final productivity revealed that the total number of tubers on one bush of the potato in the variants with growth regulators changes slightly, while the mass of tubers increases, so the variant with the growth regulator melafen increased this indicator by 37% compared to the control.
Species composition and identification of pathogens of real powdery mildew of pumpkin crops
Authors: Sletova M. E.
Published: July 2022

When cultivating pumpkin crops in most agricultural regions of the world, one of the most aggressive diseases is real powdery mildew, the damage of plants in which, under optimal soil and climatic conditions for the pathogen, reaches 100%. In the open and protected ground, among the cultivated representatives of the Cucurbitaceae family, the most widespread and harmful are the species Sphaerotheca fuliginea (Schlecht ex Fr.) Poll and Erysiphe cichoracearum f. sp. cucurbitacearum (DC ex Merat). In regions where both phytopathogens are present, mixed infections may occur, making identification difficult, and, accordingly, further plant protection measures. The pathogens of this powdery mildew of pumpkin crops have different requirements for temperature and humidity. During the growing season, there may be a change in species composition when conditions change, for example, when a new season begins. Symptoms of the disease in the form of a white or yellowish powdery plaque in the form of rounded spots (mainly on the leaves) can manifest themselves at all stages of plant development, the susceptibility of which increases by the beginning of fruiting. According to biological characteristics, S. fuliginea and E. cichoracearum are obligate biotrophic pathogens, unable to exist independently without living photosynthetic tissue, except for the wintering (sexual) stage of teleomorphs in the form of globular kleistothecia. At this stage, it is not difficult to differentiate pathogens by the morphology of kleistothecium. When analyzing the plant material of melons with the naked eye, S. fuliginea and E. cichoracearum cause similar symptoms of damage, but by microscopy these organisms can be distinguished by a complex of morphological characteristics. Taxonomically significant features are: the location of the mycelium, the formation of conidia (single or chain), the presence or absence of noticeable fibrosin bodies, the features of the appressoria, the size and shape of the conidia, as well as the position and type of their sprout tubes. The works of Russian and foreign scientists have shown the possibility of determining the types and physiological races of pathogens using an indirect method: reactions to differentiator plants. To date, about 30 physiological races of the pathogen Podosphaera xanthii (Sphaerotheca fuliginea) and 2 races of E. cichoracearum are known. However, this method does not always correlate with the methods of molecular analysis. Determination of the species composition of powdery mildew pathogens is a starting point for the development of a further strategy for the cultivation of pumpkin crops and in breeding work for resistance to this disease.
Safety of allergen immunotherapy in patients with SARS-CoV-2 infection
Authors: ATAYIK Emel , AYTEKİN Gökhan
Published: July 2022

Objectives: The aims of presenting study were trying to expose the course of SARS-CoV-2 (severe acute respiratory syndrome–related coronavirus) in patients with allergic rhinitis (AR), to compare the prevalence of SARS-CoV-2 infection, hospitalization and pneumonia rates in patients with AR receiving allergen immunotherapy (AIT) and patients did not receiving AIT (non-receivers) and to define possible risk factors for SARS-CoV-2 positivity in patients with AR.
Methods: A total of 419 patients with AR who were being followed-up in a tertiary allergy clinic between June 1, 2020 and December 31, 2020, were selected for the study.
Results: Seventy-nine (18.9%) patients became infected with the SARS-CoV-2 [32 (19.6%) patients in AR patients with AIT and 47 (18.4%) patients in non-receivers] and the rate of pneumonia was 2.4% [12.7% of SARS-CoV-2 (+) patients]. There was no significant difference was determined between the AR patients with AIT and the non-receivers in regard of the rate of SARS-CoV-2 infection, pneumonia and hospitalization (p = 0.864, p = 0.055 and p = 0.075; respectively). There was a significant difference between the groups in terms of gender, duration of disease, sensitivity to allergens (atopy) and serum IgE levels (p = 0.009, p = 0.001, p = 0.001 and p = 0.001; respectively). The accompanying comorbidities, eosinophil cout, AIT and duration of AIT were not found to be associated with an increased risk SARS-CoV-2 PCR positivity. However, female gender was shown to be associated with an decreased risk for SARS-CoV-2 PCR positivity (OR, 0.571; 95% confidence interval, 0.330-0.987; p = 0.045).Conclusions: The course of SARS-CoV-2 is similar in patients with AR who underwent AIT and patients with AR who did not undergo AIT, and AIT does not seem to increase the risk for SARS-CoV-2 infection.
Jak przygotowywano psychicznie i mentalnie żołnierzy do walki w XIX i XX stuleciu? Próba spojrzenia
Authors: Czernielewski Konrad Aleksander
Published: July 2022

W artykule omówiono, jak w różnych armiach świata przygotowywano psychicznie i mentalnie żołnierzy do walki w minionym stuleciu. Skoncentrowano uwagę głównie na II wojnie światowej, ale opisano przykłady działań militarnych w Wietnamie czy w trakcie wojen arabsko-izraelskich. Odwołano się też do przykładów wojen prowadzonych w XIX w. Omówiono kwestie przygotowania ideowego oraz roli wychowania patriotycznego. Wiele uwagi poświęcono problemom stresu pola walki czy dezercjom żołnierzy. Pominięto kwestię dezercji spowodowanych poglądami politycznymi, skupiając się jedynie na ucieczkach wywołanych strachem przed śmiercią czy kalectwem. Podjęto rozważania nad zagadnieniem: czy tak naprawdę żołnierz chce zabić wroga, czy celuje do nieprzyjaciela, chcąc go zabić? Czy tylko wykonuje rozkazy przełożonych? W artykule uwzględniono problematykę reakcji żołnierza na stratę przyjaciela. Osobnym zagadnieniem jest stosunek do zbrodni wroga na przykładzie wyzwolenia obozu koncentracyjnego w Dachau przez żołnierzy amerykańskich. Opisano także przygotowanie żołnierzy Special Operations Execitive do walki w trakcie II wojny światowej oraz innych formacji elitarnych, a zwłaszcza osób działających w konspiracji. W artykule omówiono ponadto: przygotowanie do wypełnianych misji za linią frontu, kwalifikacje fizyczne i psychiczne strzelców wyborowych oraz snajperów, przedstawiając kilku najsłynniejszych z nich, rolę dowódcy (od najniższego do najwyższego szczebla dowodzenia), zarówno na przykładach II wojny światowej, ale też wojen arabsko-izraelskich. Na koniec oceniono, jak działania wojenne, także po zakończeniu, wpływają na życie osobiste żołnierzy.
PESANTREN TANGGUH AS MODERATE ISLAMIC EDUCATION INSTITUTION DURING THE COVID-19 PANDEMIC
Authors: Rosidin Rosidin , Bachri Syabbul , Mardhatillah Masyithah , Kawakip Akhmad Nurul , Ja’far Handoko
Published: July 2022

The Covid-19 pandemic divides the attitudes of pesantren residents into three categories: very strict, very loose and moderate (tawassut). This moderate attitude is found in Pesma Al-Hikam and Pesantren Sabilurrosyad in Malang City. This article uses a qualitative approach, then analyzed from the perspective of Pierre Bourdieu’s capital theory. The purpose is to describe how the attitudes, mindset, and residents’ behavior of Pesantren Tangguh related to symbolic, cultural, social, and economic modalities, to control the pandemic crisis. The findings of this article are Pesma Al-Hikam and Pesantren Sabilurrosyad as Pesantren Tangguh are representations of moderate Islamic educational institutions during the Covid-19 pandemic in terms of Bourdieu’s capital theory. First, the nationalist-religious; adaptive and inclusive; and philosophical-rational character in terms of symbolic capital. Second, the theological view that combines destiny and endeavors harmoniously; an elastic and comparative view of Islamic law; and Sufistic behavior that combines ritual and social worship in terms of cultural capital. Third, the behaviour of pesantren residents who remain active in carrying out activities at the pesantren but are disciplined in complying with health protocols in terms of social capital. Fourth, the economic independence of the pesantren in fulfilling the needs and social assistance to the peripheral community in terms of economic capital. In summary, the residents of Pesantren Tangguh show moderate character in aspects of attitude, mindset, and behavior related to symbolic, cultural, social, and economic modalities, enabling the pesantren residents to be able to control the Covid-19 pandemic crisis well.
Numerical study of internal flue gas recirculation system applied to methane-hydrogen powered gas microturbine combustor
Authors: Fąfara Jean-Marc , Modliński Norbert
Published: July 2022

Sources of renewable energy have been increasingly used all over the world. This kind of energy is highly desirable because of its unlimited availability. Unfortunately, renewable energy production very much depends on weather conditions. Consequently, it is necessary to store the produced excess energy in order to use it when needed. There is a technology able to produce a hydrogen/methane fuel from excess renewable energy, which may be stored. This technology is called the Power-to-Gas technology (P2G). Since the efficiency of this technological process depends on the hydrogen fraction in the renewable energy fuel, there is a need to increase this fraction. Concurrently, the gas microturbine technology is increasingly widely used in various industries (aviation, energy, automotive, military, etc). The P2G technology and the gas microturbine technology are likely to be integrated in the near future and, as mentioned above, the hydrogen fraction in the methane-hydrogen fuel will tend to increase. In order to power a gas microturbine with the methane-hydrogen fuel, it will be necessary to modify the combustor to avoid an excessive temperature increase and flashbacks. In this paper it is proposed to apply an autonomous internal exhaust gas recirculation system to resolve the hydrogen combustion problems indicated above. The operating principle and the proposed design of the recirculation system and the latter’s impact on the combustor’s operating parameters and emissivity (NOx and CO) are presented.
Genetic Variation among Pharmacogenes in the Sardinian Population
Authors: Idda Maria Laura , Zoledziewska Magdalena , Urru Silvana Anna Maria , McInnes Gregory , Bilotta Alice , Nuvoli Viola , Lodde Valeria , Orru Sandro , Schlessinger David , Cucca Francesco , Floris Matteo
Published: July 2022

Pharmacogenetics (PGx) aims to identify the genetic factors that determine inter-individual differences in response to drug treatment maximizing efficacy while decreasing the risk of adverse events. Estimating the prevalence of PGx variants involved in drug response, is a critical preparatory step for large-scale implementation of a personalized medicine program in a target population. Here, we profiled pharmacogenetic variation in fourteen clinically relevant genes in a representative sample set of 1,577 unrelated sequenced Sardinians -- an ancient island population that well accounts for genetic variation in Europe as a whole and, at the same time are enriched in genetic variants that are very rare elsewhere. To this end, we used PGxPOP, a PGx allele caller based on the guidelines created by the Clinical Pharmacogenetics Implementation Consortium (CPIC), to identify the main phenotypes associated with the PGx alleles most represented in Sardinians. We estimate that 99.43% of Sardinian individuals may potentially respond atypically to at least one drug, that on average each individual is expected to have an abnormal response to about 17 drugs, and that for 27 drugs the fraction of the population at risk of atypical responses to therapy is more than 40%. Finally, we highlighted 174 pharmacogenetic variants for which the minor allele frequency is at least 10% higher among Sardinians as compared to other European populations, a fact that may contribute to substantial interpopulation variability in drug response phenotypes. This study provides baseline information for further large-scale pharmacogenomic investigations in the Sardinian population and underlines the importance of the PGx characterization of diverse than European populations as Sardinians.
Bioinformatics Analysis of Kinesin Family Member 2C in Human Tumors: Novel Prognostic Biomarker and Tumor Microenvironment Regulator
Authors: Zhang Bixi , Li Yanchun , Pang Xiaoyang , Wu Hao
Published: July 2022

Kinesin family member 2C (KIF2C) is the best-characterized member of the kinesin-13 family and is involved in accurately fine-tuned dynamics of mitotic spindles. As KIF2C is involved in both spindle formation and regulation of DNA double-strand breaks, precise regulation of KIF2C is essential to prevent malignant transformation associated with gains and losses of DNA content. In the present study, we initially reviewed The Cancer Genome Atlas database and observed that KIF2C is abundantly expressed in most tumor types. We then analyzed the gene alteration profile, protein expression, prognosis, and immune reactivities of KIF2C in more than 10,000 samples from several well-established databases. In addition, we conducted a gene enrichment set analysis to investigate the potential mechanisms underlying the role of KIF2C in tumorigenesis. Pan-cancer analysis of KIF2C demonstrated significant statistical correlations between KIF2C expression and clinical prognosis, oncogenic signature gene sets, myeloid-derived suppressor cell infiltration, ImmunoScore, immune checkpoints, microsatellite instability, and tumor mutational burden across multiple tumors. Single-cell data showed that KIF2C is abundantly expressed in malignant cells. The findings of this study provide important insight for understanding the role and mechanisms of KIF2C in tumorigenesis and immunotherapy in a variety of cancers.
Enhancing COVID Rehabilitation with Technology (ECORT): Protocol for an open-label, single site randomized controlled trial evaluating the effectiveness of electronic case management for individuals with persistent COVID-19 symptoms.
Authors: Hatcher Simon , Werier Joel , Edgar Nicole E , Booth James , Cameron William J , Corrales-Medina Vicente , Corsi Daniel , Cowan Juthaporn , Giguère Pierre , Kaluzienski Mark , Marshall Shawn , Mestre Tiago , Mulligan Bryce , Orpana Heather , Pontefract Amanda , Stafford Darlene , Thavorn Kednapa , Trudel Guy
Published: July 2022

Background: As of May 2022, Ontario has seen more than 1.3 million cases of COVID-19. While the majority of individuals will recover from infection within four weeks, a significant subset experience persistent and often debilitating symptoms, known as “post-COVID syndrome” or “Long COVID”. Those with Long COVID experience a wide array of symptoms, with variable severity, including fatigue, cognitive impairment, and shortness of breath. Further, the prevalence and duration of Long COVID is unclear, nor is there evidence on the best course of rehabilitation for individuals to return to their desired level of function. Previous work with chronic conditions has suggested that the addition of electronic case management (ECM) may help to improve outcomes. These platforms provide enhanced connection with care providers, detailed symptom tracking and goal setting, and access to relevant resources. In this study, our primary aim is to determine if the addition of ECM with health coaching improves Long COVID outcomes at three months compared to health coaching alone.Methods: The trial is an open-label, single site, randomized controlled trial of ECM with health coaching (ECM+) compared to health coaching alone (HC). Both groups will continue to receive usual care. Participants will be randomized equally to receive health coaching (+/- ECM) for a period of 8 weeks and a 12-week follow-up. Our primary outcome is the WHO Disability Assessment Scale (WHODAS), 36-item self-report total score. Participants will also complete measures of cognition, fatigue, breathlessness, and mental health. Participants and care providers will be asked to complete a brief qualitative interview at the end of the study to evaluate acceptability and implementation of the intervention.Discussion: There is currently little evidence about the optimal treatment of Long COVID patients or the use of digital health platforms in this population. The results of this trial could result in rapid, scalable, and personalized care for people with Long COVID which will decrease morbidity after an acute infection. Results from this study will also inform decision making in Long COVID and treatment guidelines at provincial and national levels.Trial registration: ClinicalTrials.gov, NCT05019963, Registered on 25 August 2021, https://clinicaltrials.gov/ct2/show/NCT05019963