bluuebunny/crossref_metadata_2025 huggingface dataset:
Suppression of Switched Reluctance Motor Vibration of In-Wheel Motor Electric Vehicle
Authors: Yang Funing , Wang Yanyang
Published: November 2018

Switched reluctance motor (SRM) has got great attention in in-wheel motor electric vehicle (IWM-EV), but SRM vertical force, the vertical component of SRM unbalanced radial force, yields SRM vertical vibration and does harm to dynamic performance of IWM-EV. In order to reduce the SRM vertical vibration, electromagnetic active suspension and a linear quadratic Gaussian (LQG) controller were used to suppress the unbalanced radial force in this paper. All the models and the controller were constructed in Matlab/Simulink R2015b. The controller considers five performance indexes: vehicle body acceleration, SRM airgap eccentricity, SRM stator acceleration, suspension dynamic deflections, and tyre deformation. Analytic Hierarchy Process (AHP) was used to calculate the weighted coefficients of performance indexes. Simulations indicate that this electromagnetic active suspension can reduce SRM vertical vibration obviously and improve dynamic performance of IWM-EV.
Investigation of Outbreak-Specific Nonsynonymous Mutations on Ebolavirus GP in the Context of Known Immune Reactivity
Authors: Vaughan Kerrie , Xu Xiaojun , Peters Bjoern , Sette Alessandro
Published: November 2018

The global response to the most recent EBOV outbreak has led to increased generation and availability of data, which can be globally analyzed to increase our understanding of immune responses to EBOV. We analyzed the published antibody epitope data to identify regions immunogenic for humans on the main GP antigenic target and determine sequence variance/nonsynonymous mutations between historical isolates and variants from the 2013-2016 outbreak. Approximately half of the GP sequence has been reported as targeted by antibody responses. Our results show an enrichment of nonsynonymous mutations (NSMs) within epitopic regions on GP (70%, p=0.0133). Mapping NSMs to human epitope reactivity may be useful for future therapeutic and prophylaxis development as well as for our general understanding of immunity against EBOV.
Medium-Long-Term Clinical and Radiographic Outcomes of Minimally Invasive Distal Metatarsal Metaphyseal Osteotomy (DMMO) for Central Primary Metatarsalgia: Do Maestro Criteria Have a Predictive Value in the Preoperative Planning for This Percutaneous Technique?
Authors: Biz Carlo , Corradin Marco , Kuete Kanah Wilfried Trepin , Dalmau-Pastor Miki , Zornetta Alessandro , Volpin Andrea , Ruggieri Pietro
Published: November 2018

Background. The purpose of this prospective study was first to evaluate the safety and effectiveness of Minimally Invasive Distal Metatarsal Metaphyseal Osteotomy (DMMO) in treating central metatarsalgia, identifying possible contraindications. The second objective was to verify the potential of DMMO to restore a harmonious forefoot morphotype according to Maestro criteria. Methods. A consecutive series of patients with metatarsalgia was consecutively enrolled and treated by DMMO. According to Maestro criteria, preoperative planning was carried out by both clinical and radiological assessment. Patient demographic data, AOFAS scores, 17-FFI, MOXFQ, SF-36, VAS, and complications were recorded. Maestro parameters, relative morphotypes, and bone callus formation were assessed. Statistical analysis was carried out (p < 0.05). Results. Ninety-three patients (93 feet) with a mean age of 62.4 (31-87) years were evaluated. At mean follow-up of 58.7 (36-96) months, all of the clinical scores improved significantly (p < 0.0001). Most of the osteotomies (76.3%) had healed by 3-month follow-up, while ideal harmonious morphotype was restored only in a few feet (3.2%). Clinical and radiological outcomes were not different based on principal demographic parameters. Long-term complications were recorded in 12 cases (12.9%). Conclusion. DMMO is a safe and effective method for the treatment of metatarsalgia. Although Maestro criteria were useful to calculate the metatarsal bones to be shortened and a significant clinical improvement of all scores was achieved, the ideal harmonious morphotype was restored only in a few feet. Hence, our data show that Maestro criteria did not have a predictive value in clinical outcomes of DMMO.
Mechanisms Underlying Aggressive Behavior Induced by Antiepileptic Drugs: Focus on Topiramate, Levetiracetam, and Perampanel
Authors: Hansen Cerine C. , Ljung Hanna , Brodtkorb Eylert , Reimers Arne
Published: November 2018

Antiepileptic drugs (AEDs) are effective against seizures, but their use is often limited by adverse effects, among them psychiatric and behavioral ones including aggressive behavior (AB). Knowledge of the incidence, risk factors, and the underlying mechanisms of AB induced by AEDs may help to facilitate management and reduce the risk of such side effects. The exact incidence of AB as an adverse effect of AEDs is difficult to estimate, but frequencies up to 16% have been reported. Primarily, levetiracetam (LEV), perampanel (PER), and topiramate (TPM), which have diverse mechanisms of action, have been associated with AB. Currently, there is no evidence for a specific pharmacological mechanism solely explaining the increased incidence of AB with LEV, PER, and TPM. Serotonin (5-HT) and GABA, and particularly glutamate (via the AMPA receptor), seem to play key roles. Other mechanisms involve hormones, epigenetics, and “alternative psychosis” and related phenomena. Increased individual susceptibility due to an underlying neurological and/or a mental health disorder may further explain why people with epilepsy are at an increased risk of AB when using AEDs. Remarkably, AB may occur with a delay of weeks or months after start of treatment. Information to patients, relatives, and caregivers, as well as sufficient clinical follow-up, is crucial, and there is a need for further research to understand the complex relationship between AED mechanisms of action and the induction/worsening of AB.
Reducing Blood Loss in Revision Total Hip and Knee Arthroplasty: Tranexamic Acid Is Effective in Aseptic Revisions and in Second-Stage Reimplantations for Periprosthetic Infection
Authors: Reichel Franz , Peter Christoph , Ewerbeck Volker , Egermann Marcus
Published: November 2018

Introduction. The aim of the study was to determine the usefulness of tranexamic acid (TXA) in revision total hip arthroplasty (rTHA) and revision total knee arthroplasty (rTKA). We analyzed the perioperative blood loss with and without TXA in aseptic rTHA and rTKA as well as in second-stage reimplantation for hip and knee periprosthetic infection. Materials and Methods. In this prospective cohort study, 147 patients receiving TXA (96 rTHA, 51 rTKA) were compared to a retrospective cohort of 155 patients without TXA (103 rTHA, 52 rTKA). The TXA regimen consisted of a preoperative bolus of 10 mg/kg bodyweight (BW) TXA plus 1 mg/kgBW/h perioperatively. Given blood products were documented and the perioperative blood loss was calculated. Thromboembolic events were registered until three months postoperatively. In subgroups, the effects of TXA were separately analyzed in 215 aseptic revisions as well as in 87 reimplantations in two-stage revisions for periprosthetic infection. Results. Both TXA groups showed a significantly reduced mean blood loss compared to the respective control groups. The TXA group of rTHA patients had a mean blood loss of 2916 ml ± 1226 ml versus 3611 ml ± 1474 ml in the control group (p<.001). For the TXA group of rTKA patients, mean calculated blood loss was 2756 ml ± 975 ml compared to 3441 ml ± 1100 ml in the control group (p=.0012). A significantly reduced blood loss was also found in the TXA subgroups for aseptic and septic revision procedures. No thromboembolic events were recorded among the TXA groups. Conclusions. There is a significant reduction of perioperative blood loss under TXA influence without an increased incidence of adverse events. The standard use of TXA can be recommended in aseptic hip and knee revision arthroplasties as well as in second-stage reimplantations for periprosthetic infection.
Identification of Hypotensive Biofunctional Compounds of Coriandrum sativum and Evaluation of Their Angiotensin‐Converting Enzyme (ACE) Inhibition Potential
Authors: Hussain Farieha , Jahan Nazish , Rahman Khalil-ur- , Sultana Bushra , Jamil Saba
Published: November 2018

The aim of this study was to identify and characterize the bioactive compounds of Coriandrum sativum responsible for the treatment of hypertension and to explore their mechanism of action as angiotensin‐converting enzyme (ACE) inhibitors. Bioactive fractions like alkaloids, flavonoids, steroids, and tannins were extracted and evaluated for their ACE inhibition potential. Among them, only flavonoid‐rich fraction showed high ACE inhibition potential with IC50 value of 28.91 ± 13.42 μg/mL. The flavonoids were characterized through LC‐ESI‐MS/MS. Seventeen flavonoids were identified in this fraction of Coriandrum sativum in negative ionization mode which includes pinocembrin, apigenin, pseudobaptigenin, galangin‐5‐methyl ether, quercetin, baicalein trimethyl ether, kaempferol dimethyl ether, pinobanksin‐5‐methylether‐3‐O‐acetate, pinobanksin‐3‐O‐pentenoate, pinobanksin‐3‐O‐phenylpropionate, pinobanksin‐3‐O‐pentanoate, apigenin‐7‐O‐glucuronoide, quercetin‐3‐O‐glucoside, apigenin‐3‐O‐rutinoside, rutin, isorhamnetin‐3‐O‐rutinoside, and quercetin dimethyl ether‐3‐O‐rutinoside, while six flavonoids including daidzein, luteolin, pectolinarigenin, apigenin‐C‐glucoside, kaempferol‐3‐7‐dimethyl ether‐3‐O‐glucoside, and apigenin‐7‐O‐(6‐methyl‐beta‐D‐glucoside) were identified in positive ionization mode. The results of this study revealed that Coriandrum sativum is a valuable functional food that possesses a number of therapeutic flavonoids with ACE inhibition potential that can manage blood pressure very efficiently.
Multiobjective Optimization Approach for Coordinating Different DG from Distribution Network Operator
Authors: Zhang Limei , Yang Honglei , Lv Jing , Liu Yongfu , Tang Wei
Published: November 2018

Integrating with analysis of uncertainties, this paper presented a multiobjective optimization approach for coordinating different DG from the perspective of Distribution Network Operator (DISOPER). Aiming to three uncertain factors including fuzzy variable, random variable, and interval variable, the information entropy and interval analysis methods are adopted to construct multistate models of multisource uncertainty. The information entropy method is to convert fuzzy variable into equivalent random variable. Interval analysis method is to transform random variables into interval variables by setting a confidence level. Then plenty of simulation analysis based on the small probability event and expectation are investigated to reduce the computational burden and eliminate invalid computation. Subsequently, multiobjective formulations based on multistate are built by analyzing systematical power loss, voltage quality, reliability, and environment change provide some reference for DISOPER in dealing with access of privately owned DG units. Furthermore, based on network topology analysis and modified nondominated sorting genetic algorithm (NSGA), a combinatorial optimization method is proposed to reduce search space and solve the constructed formulations efficiently. Simulations are carried out on IEEE 37-bus systems and results are presented and discussed.
Effect of Adjacent Hole on the Blast‐Induced Stress Concentration in Rock Blasting
Authors: Yang Yuezong , Shao Zhushan , Mi Junfeng , Xiong Xiaofeng
Published: November 2018

To investigate the effect of an adjacent hole on the blast‐induced stress concentration in rock blasting, a rock blasting model with an adjacent hole is explored through theoretical analysis and numerical simulation. The commercial software LS‐DYNA is utilized to simulate adjacent hole effect in rock blasting, in which the Johnson–Holmquist concrete material model is used to simulate rock and the high‐explosive‐burn‐explosive and the equation of state of JWL are used to simulate explosive. Influences of the key parameters of adjacent hole effect in rock blasting, pitch of holes, adjacent hole diameter, and uncoupled medium in a blasting hole are extensively explored. According to the simulation results, when the explosion stress wave spreads to the adjacent hole wall, the tangential stress on the adjacent hole wall induced by the explosion stress wave is always greater than the radial stress. Adjacent hole diameter has a major effect on stress concentration, but with the adjacent hole diameter increasing, the stress concentration phenomenon weakens and the free surface effect of the adjacent hole plays a more important role.
Effect of Loading Direction and Slope on Laterally Loaded Pile in Sloping Ground
Authors: Jiang Chong , He Jia-Li , Liu Lin , Sun Bo-Wen
Published: November 2018

A series of three‐dimensional finite element analyses were performed to study the behavior of piles in sloping ground under undrained lateral loading conditions. The analyses have been conducted for slopes with different angles and two loading directions. The obtained results show that as the slope increases, it can cause greater lateral displacement and internal force of the pile. In addition, the increase of the slope ratio will cause the position of the maximum bending moment and soil resistance zero point of the pile to move downward, further increasing the pile deflection. Furthermore, when the pile distance from slope crest B < 7D, the displacement and internal force development of the pile under toward loading is more obvious. When the pile distance from the slope crest exceeds 7D, the effect of loading direction on the pile can be neglected.
A Global Sensitivity Analysis of Dynamic Loading and Route Selection Parameters on Network Performances
Authors: Duruisseau Charlotte , Leclercq Ludovic
Published: November 2018

We conduct a Global Sensitivity Analysis (GSA) of urban-scale network performances to parameters representing a wide range of realistic dynamic loadings, decomposed in a choice of OD matrix, routing alternatives, and paths flow distribution. A special attention is given to the route alternatives generation, where overlapping metrics and selection methods are introduced to reproduce a wide variety of paths sets configuration. Paths flow distributions are calculated based on different equilibrium criteria. Several sets of simulations are conducted and analyzed graphically and then with a variance-based GSA method so as to get insights on how much and in which conditions each network loading parameter influences network performances by itself or by interaction. Results notably reveal that the demand level is the most decisive parameter since low values simply lead to free-flow conditions with no influence of the other parameters, whereas higher values lead to a wide diversity of network states going from close to capacity but stable to gridlocked. While a nonnegligible amount of this disparity is explained by the demand pattern parameter, the number of paths per OD, their overlapping, and the equilibrium criterion of the paths flow distribution are still influential enough to maintain the network close to its optimal capacity or to prevent the network from fast collapse (gridlock). The highlighted connection between spatial and temporal heterogeneities of the network states explains the gridlocking phenomena. These extracted insights are very encouraging for operational implementations.
Fasting Plasma Glucose Indicates Reversibility of the Acute Insulin Response after Short-Term Intensive Insulin Therapy in Patients with Various Duration of Type 2 Diabetes
Authors: Liu Liehua , Yang Siyue , Liu Jianbin , Li Hai , Liu Juan , Cao Xiaopei , Xiao Haipeng , Li Yanbing
Published: November 2018

Recovery of acute insulin response (AIR) is shown to be associated with long-term outcomes of patients with early type 2 diabetes treated with short-term intensive insulin therapy (SIIT). However, the complexity of measuring an AIR limits its utility in a real-world clinical setting. The aim of the study was to assess fasting indicators that may estimate recovery of the AIR after SIIT. We enrolled 62 patients with type 2 diabetes mellitus (T2DM) of varying disease duration who had poor glycemic control. Participants were treated with SIIT using insulin pumps to achieve near normoglycemia for 7 days. The AIR before and after the therapy were measured by intravenous glucose tolerance tests. After the therapy, AIR increased from −16.7 (−117.4, 52.4) pmol/L·min to 178.7 (31.8, 390.7) pmol/L·min (P<0.001) while hyperglycemia was alleviated; this improvement was observed in all disease duration categories. AIR was almost absent when fasting plasma glucose (FPG) > 10 mmol/L, while both AIR (R=−0.53, P<0.001) and its improvement from baseline (△AIR, R=−0.52, P<0.001) were negatively associated with FPG after SIIT when FPG < 10 mmol/L. In multivariate analyses, FPG after SIIT and baseline fasting C peptide were independent indicators of both AIR after the therapy and ∆AIR; HDL-C after the therapy also predicted AIR after the therapy. We concluded that recovery of the AIR could be obtained in T2DM patients of varying disease duration by SIIT and it could be conveniently estimated using posttreatment fasting plasma glucose and other fasting indicators.
Steroidale und nichtsteroidale Antiphlogistika bei Epitheldefekten nach cornealem Crosslinking - Komplikationen bei der Keratokonus-Therapie
Authors: Bachmann Björn
Published: November 2018

We report a case of corneal melting through sterile infiltration presumably due to excessive use of nonsteroidal anti-inflammatory eye drops after corneal crosslinking (CXL). It was treated using steroids combined with amniotic membrane transplantation (AMT). A 33-year-old man with progressing keratoconus underwent left eye CXL. We prescribed betamethasone and levofloxacin eye drops 5 times daily and diclofenac sodium eye drops 3 times daily for 3 days. Three days after CXL, there was a persistent epithelial defect and the left corneal stroma was clouded. His visual acuity remained unchanged. We prescribed betamethasone hourly and 20 mg prednisolone daily. At 1 week after CXL, the corneal epithelial defect and infiltration were unchanged. He had not stopped using diclofenac at the prescribed time. On day 17, we performed AMT and his cornea and visual acuity improved. AMT may be effective against persistent epithelial defects and corneal melting after CXL.
Recovery of miR-139-5p in Ovarian Cancer Reverses Cisplatin Resistance by Targeting C-Jun
Authors: Jiang Ying , Jiang Jing , Jia Haiqing , Qiao Zhiwei , Zhang Jingru
Published: November 2018

Background/Aims: In platinum-based chemotherapy for ovarian cancer, acquired drug resistance is a frequent occurrence. Because recent studies have demonstrated that dysregulation of microRNAs (miRNAs) is partly responsible for the induction of acquired drug resistance in cancers, we hypothesized that correcting the dysregulation of key miRNAs would reverse the acquired resistance to platinum-based drugs in ovarian cancer. Methods: Cisplatin-resistant SKOV3 and A2780 ovarian cancer cell lines (SKOV3-R and A2780-R, respectively) were established by long-term exposure to cisplatin. MTT assays were performed to evaluate the viability of SKOV3, SKOV3-R, A2780, and A2780-R cells. Quantitative PCR was used to examine the expression of miR-139-5p in these cell lines. The regulatory mechanism was confirmed by western blot analysis and luciferase reporter assays. After treatment with miR-139-5p and cisplatin, mitochondrial membrane potential and apoptosis were measured by using flow cytometry. Interaction with c-Jun and activating transcription factor 2 (ATF2) was evaluated by co-immunoprecipitation. Expression of B-cell lymphoma-extra large (Bcl-xl) and activation of caspase-9 and caspase-3 were detected by western blotting. Results: Expression of miR-139-5p was decreased in SKOV3-R and A2780-R cells. Recovery of miR-139-5p increased the sensitivity of SKOV3-R and A2780-R cells to cisplatin treatment, inhibited the interaction of c-Jun and ATF2, and decreased Bcl-xl expression in SKOV3-R and A2780-R cells. Expression of miR-139-5p promoted cisplatin-induced mitochondrial apoptosis through binding the 3′ untranslated region of c-Jun mRNA. Conclusion: Recovery of miR-139-5p suppressed the expression of c-Jun and thus reversed cisplatin-resistance in ovarian cancer.
Calcium Supplementation Enhanced Adipogenesis and Improved Glucose Homeostasis Through Activation of Camkii and PI3K/Akt Signaling Pathway in Porcine Bone Marrow Mesenchymal Stem Cells (pBMSCs) and Mice Fed High Fat Diet (HFD)
Authors: Zhang Fenglin , Ye Jingjing , Meng Yingying , Ai Wei , Su Han , Zheng Jisong , Liu Fangfang , Zhu Xiaotong , Wang Lina , Gao Ping , Shu Gang , Jiang Qingyan , Wang Songbo 
Published: November 2018

Background/Aims: It has been implicated that calcium supplementation is involved in reducing body weight/fat and improving glucose homeostasis. However, the underlying mechanisms are still not fully understood. Here, we investigated the effects of calcium supplementation on adipogenesis and glucose homeostasis in porcine bone marrow mesenchymal stem cells (pBMSCs) and high fat diet (HFD)-fed mice and explored the involved signaling pathways. Methods: In vitro, pBMSCs were treated with 4 mM extracellular calcium ([Ca2+]o) and/or 1 μM nifedipine, 0.1 μM BAPTA-AM, 1 μM KN-93, 50 nM wortmannin for 10 days. The intracellular calcium ([Ca2+]i) levels were measured using Fluo 3-AM by flow cytometry. The adipogenic differentiation of pBMSCs was determined by Oil Red-O staining and triglyceride assay. The expression of marker genes involved in adipogenesis (peroxisome proliferator activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα)) and glucose uptake (glucose transporter 4 (GLUT4)), as well as the activation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) and PI3K/Akt-FoxO1/AS160 signaling pathways were determined by Western blotting. Glucose uptake and utilization were examined using 2-NBDG assay and glucose content assay, respectively. In vivo, C57BL/6J male mice were fed a HFD (containing 1.2% calcium) without or with 0.6% (w/w) calcium chloride in drinking water for 13 weeks. The adipogenesis, glucose homeostasis and the involvement of CaMKII and PI3K/Akt signaling pathway were also assessed. Results: In vitro, [Ca2+]o stimulated pBMSCs adipogenesis by increasing [Ca2+]i level and activating CaMKII and PI3K/Akt-FoxO1 pathways. In addition, [Ca2+]o promoted glucose uptake/utilization by enhancing AS160 phosphorylation, GLUT4 expression and translocation. However, the stimulating effects of [Ca2+]o on pBMSCs adipogenesis and glucose uptake/utilization were abolished by L-VGCC blocker Nifedipine, [Ca2+]i chelator BAPTA-AM, CaMKII inhibitor KN-93, or PI3K inhibitor Wortmannin. In vivo, calcium supplementation decreased body weight and fat content, increased adipocyte number, and improved glucose homeostasis, with elevated PPARγ and GLUT4 expression and PI3K/Akt activation in iWAT. Conclusion: calcium supplementation enhanced adipogenesis and glucose uptake in pBMSCs, which was coincident with the increased adipocyte number and improved glucose homeostasis in HFD-fed mice, and was associated with activation of CaMKII and PI3K/Akt-FoxO1/AS160 pathways. These data provided a broader understanding of the mechanisms underlying calcium-induced body weight/fat loss and glycemic control.
Type III Interferons in Viral Infection and Antiviral Immunity
Authors: Zhou Jian-hua , Wang Yi-ning , Chang Qiu-yan , Ma Peng , Hu Yonghao , Cao Xin
Published: November 2018

Interferons (IFNs) can serve as the first line of immune defense against viral infection. The identification of IFN-λs 1, 2, 3 & 4 (termed as type III IFNs) has revealed that the antiviral immune response to viruses contains more components than the type I IFNs that have been known for more than 50 years. IFN-λs are IFN-λ1 (IL-29), IFN-λ2 (IL-28a), IFN-λ3 (IL-28b) and IFN-λ4, which resembles IFN-λ3. IFN-λs have type I-IFN-like immune responses and biological activities, but our knowledge of these novel players in the antiviral response is not well established. In this review, we try to describe the current information on the expression and function of IFN-λs in the innate antiviral immune defense and IFN-λ2’s role in regulating and shaping the adaptive immune response. We suggest that IFN-λs are key antiviral cytokines, directly performing an antiviral immune response at epithelial surfaces in the early stages of viral infection, and that these cytokines also skew the balance of Th1 and Th2 cells to Th1 phenotype. In addition, genetic polymorphisms in IFN-λ genes can impair antiviral immune responses in clinical treatment.
Fare pragmatica nella scuola primaria: uno studio esplorativo sulle richieste
Authors: Ferrari Stefania , Zanoni Greta
Published: November 2018

O artigo ilustra um estudo exploratório sobre as modalidades de produção do ato comunicativo do pedir na interação de crianças de 8-9 anos, baseado em uma experimentação educacional de pesquisa-ação, conduzida na Itália na turma curricular da escola primária. Os aspectos especificamente indagados são os seguintes: as modalidades de realização do ato comunicativo; a relação entre ato comunicativo e sequência interacional; a capacidade das crianças de refletir sobre os usos linguísticos. Os resultados obtidos oferecem indicações para o desenvolvimento de materiais didáticos apropriados e para a definição de futuros protocolos de pesquisa.
A semântica do "futuro no passado" em língua italiana
Authors: Freitas Paula Garcia de
Published: November 2018

The ‘future in the past’ is a structure of the Italian language with which Brazilian learners seem to present learning difficulties. One can say, then, that it is a complex structure for them. In an attempt to better understand the relations of meaning that are established for the formation of the ‘future in the past’ of the Italian language and to illustrate such relations for Brazilian learners, we propose this article, which is divided into three parts: the first part, which aims at contextualizing the research, deals with relations that are established between the moments of the event, of the enunciation and of reference; the second part deals specifically with the ways in which it is possible to express the ‘future in the past’; and the third and last part seeks to illustrate the semantic relations for the construction of such structure. The conclusion we reached is that the ‘future in the past’ presents peculiarities in relation to Portuguese and understanding the semantic relations that are established for its elaboration can facilitate its learning.
LEIBNIZ COMPATIBILISTA: A AÇÃO LIVRE ENTRE O INDETERMINISMO E O FATALISMO
Authors: Borges Junior Eli
Published: November 2018

No “labirinto da liberdade”, interessante é a solução apresentada por Leibniz como forma de assegurar uma ação humana livre sem que essa desafie, em qualquer medida, a vontade e a presciência divinas. No presente artigo, pretendemos, assim, refletir, ainda que brevemente, sobre como o filósofo delineia e compatibiliza as ideias, à primeira visada paradoxais, de liberdade e determinação. Veremos como Leibniz, em última instância, acaba por garantir uma ação em que a liberdade se inscreve entre a necessidade e a contingência, o que a torna, por consequência, moralmente responsável.
TEXTO E CONTEXTO: A DUPLA LÓGICA DO DISCURSO FILOSÓFICO
Authors: Chaui Marilena De Souza
Published: November 2018

A pesquisa em história da filosofia visa compreender de onde o filósofo fala, a quem se dirige, contra quem escreve, por que decidiu escrever e os efeitos de sua escrita, unificando texto e contexto. Por isso, se distingue da leitura rigorosa que caracteriza o procedimento estrutural. Inaugurada como disciplina filosófica por Hegel, a história da filosofia foi interpretada de maneiras diferentes pela posição relativista, pela posição estrutural francesa (iniciada por Brèhier, Guéroult e Goldshmidt) e por Merleau-Ponty. Este propõe a noção de “impensado” das obras de pensamento, como o excesso da obra, aquilo que dá a pensar e mantém a obra aberta. É esse impensado que nos abre a possibilidade de interrogar nosso próprio presente. Claude Lefort, aluno de Merleau-Ponty, vê como um enigma da obra de pensamento a possibilidade de suscitar discursos. E conclui que se escrever e interpretar são o mesmo, ler e interpretar também são o mesmo.
ELEMENTOS DA LIBERDADE REPUBLICANA EM JOHN LOCKE
Authors: Sousa Rodrigo Ribeiro de
Published: November 2018

Ao longo da história da filosofia, John Locke tem sido frequentemente associado à tradição do liberalismo político, o que decorre, invariavelmente, de um modo peculiar de interpretação da noção de liberdade para o filósofo, que estaria estruturada em torno da ideia de não-interferência. Derivada frequentemente de propostas analíticas realizadas em um “vácuo histórico”, em que as ideias de Locke são tomadas como uma estática coleção, tal conclusão expressa uma perspectiva que não considera o caráter essencialmente discursivo da filosofia política e o “campo problemático” em que os conceitos foram pensados pelo filósofo. Diante dessa perspectiva, o propósito deste artigo é o de realçar, na linguagem política utilizada pelo filósofo, os elementos contextuais que permitem a compreensão dos argumentos desenvolvidos pelo autor como parte de uma performance – na acepção proposta por John Pocock –, a fim de destacar os aspectos que indicam a possibilidade de aproximação do conceito de liberdade de Locke da ideia de liberdade republicana, descrita por Philip Pettit a partir da ideia de não-dominação, sem descuidar da análise das evidências textuais que indicam a presença de argumentos na obra do autor que compõem o cerne da concepção republicana de liberdade.
O CONCEITO DE LIBERDADE E SUAS IMPLICAÇÕES POLÍTICAS. NOTAS SOBRE SIDNEY, LOCKE E A TRADIÇÃO REPUBLICANA
Authors: Hamel Christopher
Published: November 2018

Neste artigo o autor relaciona os pensamentos políticos de Locke e Sidney para defender que Locke não pode ser inserido na tradição republicana da qual os escritos de Sidney fazem parte. Isto porque: 1) inexiste na teoria política lockeana uma visão de que a virtude cívica seja o suporte para instituições livres, tal como existe na referida tradição evocada por Sidney; 2) Locke reconhece o fundamento constitucional da prerrogativa do rei, o que para os republicanos, Sidney entre eles, é incompatível com a liberdade; 3) Locke retrata um povo excessivamente cordato e permissivo com o uso do poder por parte do governante, e também pouco disposto ao exercício do  direito de resistência. Diferentemente, Sidney recorre à história para defender que os povos livres revelam as qualidades necessárias para conduzir essa resistência, já que o reconhecimento de que o governo de si mesmo  e a resistência à tirania é uma questão de dignidade do homem como ser de liberdade.
HISTÓRIA NATURAL E ATEÍSMO ANTROPOLÓGICO EM JOHN LOCKE
Authors: Silva Saulo Henrique Souza
Published: November 2018

O objetivo deste artigo é dar relevo à presença da argumentação histórica e antropológica nas obras publicadas por John Locke entre 1689 e 1695. Essa orientação defende a existência de uma diversidade de povos e costumes ao redor do mundo, tomando como base as comunidades longínquas descritas nos relatos de viagens. Entre os tipos de povos considerados por Locke, existem sociedades ateias, idólatras, de moral filosófica e, poder-se-ia dizer, culmina com a defesa do cristianismo como a religião mais apropriada para educar os trabalhadores das sociedades de apropriação ampliada.
LOCKE E O DIREITO DOS POBRES
Authors: Nascimento Christian Lindberg Lopes do
Published: November 2018

A Inglaterra vivida por Locke é marcada, contraditoriamente, pelo crescimento da pobreza num cenário de prosperidade econômica. Esta situação fez com que o Estado investisse em políticas assistenciais, fato observado por ele com certa ressalva, já que o filósofo inglês diagnosticou que a pobreza é fruto da degeneração moral que marcava uma parcela da sociedade. Entretanto, sabe-se que o conceito lockeano de propriedade garante o direito à vida como natural a todos, direito garantindo mesmo após a passagem para a sociedade contratual. Esta situação o conduz a refletir sobre o direito dos pobres, particularmente no intitulado Ensaio sobre a lei assistencial. Tendo como cerne o conceito de caridade, o objetivo deste texto é expor a reflexão que Locke desenvolve em torno do direito dos pobres.
JOHN LOCKE E AS TEORIAS DO DIREITO DE RESISTÊNCIA DE MATRIZ LUTERANA
Authors: Nunes Silvio Gabriel Serrano
Published: November 2018

Pretende-se abordar como os argumentos luteranos ─ de natureza constitucional das "magistraturas inferiores" e de direito privado ─ acerca do direito de resistência, desenvolvidos no final da década de 1520 e início de 1530, foram recepcionados no Segundo Tratado Sobre o Governo Civil, de John Locke, escrito no século XVII. O argumento de direito privado compreende que todo governante que abandona as boas ações e se dedica a cometer atos tirânicos se despoja de sua autoridade e, consequentemente, deve ser tratado como uma pessoa privada, portanto, sujeita ao lícito revide, o que configura uma espécie de legítima defesa. O argumento constitucional das "magistraturas inferiores" afirma a possibilidade de órgãos intermediários (agentes políticos como corpos legislativos e judiciais) entre o governante e o povo estarem legitimados para oferecer resistência às tiranias. Em John Locke, ambos os argumentos objetivam a solução do problema da tirania para se obter liberdade política e religiosa.
Manoel Ferreira de Araújo Guimarães (1777-1838): Elementos necessários para uma revisão da História da Matemática no Brasil
Authors: Trentin Paulo Henrique
Published: November 2018

Este artigo refere-se ao primeiro trabalho produzido a partir do aprofundamento que realizaremos ao longo dos dois anos de pesquisa em nível de pós-doutoramento, na Universidade de São Paulo. Assim, caracterizamos aspectos sobre Manoel Ferreira de Araújo Guimarães, do seu nascimento em 1777 à sua chegada a universidade em Portugal. Primeiramente, trazemos apontamentos referentes a sua formação e o papel de seu pai em sua carreira. Observamos os apontamentos em publicações brasileiras do período relativas a História da Educação e a História da Matemática Brasileira, servindo como referências para que afirmemos que deva haver uma revisão historiográfica nestes campos de pesquisa. A base para esta afirmação situa-se nas análises dos escritos que mencionam Manoel Ferreira de Araújo Guimarães. Concluímos esse texto com pontos que desenvolveremos em outros dois escritos que realizaremos. Nos próximos textos, identificaremos a teia de relações sociais, políticas que envolveram nossa personagem, tendo por objetivo realizar uma releitura do período brasileiro entre 1777 e 1838, em que ela viveu e constituiu uma série de identidades, tais como; professor, tradutor, editor-chefe e político.
Interpretação de temas de “margem”, literaturas e culturas em perspectiva comparada
Authors: Borba Maria Antonieta Jordão de Oliveira
Published: November 2018

Este artigo retoma o conceito de “interpretação” derivado das reflexões da Desconstrução francesa, mais especificamente das ideias de Michel Foucault e Jacques Derrida, de modo a não só abastecer pesquisas sobre conteúdos que emergem “à margem”, como também contribuir para o entendimento da formação de identidade de culturas da dependência. Estendendo as reflexões dos filósofos para uma releitura da colonização brasileira será desenvolvida uma exposição pela qual se pretende revelar como a proposta de Literatura comparada de Silviano Santiago é capaz de promover nova perspectiva de compreensão da identidade de países como o Brasil e os da América latina.
Peregrinaciones poéticas por el áspero mundo
Authors: Santos Margareth Dos
Published: November 2018

O artigo discute a poética de Ángel González e se centra no volume Tratado de Urbanismo (1967). O debate dessa obra, representativa na esfera das reflexões do poeta sobre o homem e seu entorno, pretende materializar sua profunda indagação sobre a realidade espanhola circundante.Esperamos que o estudo do núcleo de Tratado de urbanismo demonstre como o autor nos apresenta uma crônica dos “anos triunfais” franquistas, além de lanzar no panorama literario de la época um debate inusitado entre o sujeito poético e sua experiência no mundo, no qual, seus versos adquirem a amplitude de uma “narrativa poética” que nos desvela o lado mais sombrio do suposto triunfalismo em que o “áspero mundo” da ditadura franquista se mostra em extensão e amplitude em seus detalhes mais sórdidos.
Rüsen’s Response to the Crisis of Historicism
Authors: Wiklund Martin
Published: November 2018

Although Rüsen only discusses the crisis of historicism explicitly in his work occasionally, his general perspective on historical knowledge can be interpreted as a response to the crisis. Different responses to the crisis of historicism correspond to different interpretations of its main problems. In order to specify Rüsen’s response, a number of aspects of his perspective are pointed out as solutions to such problems. Indirectly, the analysis discloses problems that any plausible attempt to come to terms with the crisis of historicism ought to handle. By identifying differences to other contemporary responses to the crisis of historicism, the continuing relevance of Rüsen’s approach is demonstrated.
Jörn Rüsen y el humanismo como luz en tiempos de oscuridad
Authors: Kozlarek Oliver
Published: November 2018

En una primera sección de este artículo quisiera explicar las diferencias entre tres conceptos que me parecen centrales no solamente para la comprensión de las ideas de Rüsen, sino también para actualizar un humanismo en el siglo xxi. Como ya señalé: el humanismo no es para Rüsen una ocurrencia intelectual. Se trata más bien del resultado de una evolución histórica. En la segunda sección trataré de reconstruir la génesis histórica del humanismo de Rüsen. Quedará claro que las ideas de Rüsen sobre el humanismo se inspiran antes que nada en la tradición del pensamiento occidental y sobre todo europeo. De esta manera, me parece indispensable relacionarlas con las críticas postcoloniales que han recobrado justificadamente mucha importancia. En la tercera sección me propongo discutir este plexo temático. La posición que Rüsen asume frente a la crítica postcolonial prepara el terreno para explicar su propuesta para un “humanismo en la época de la globalización”, en la que repararé en la cuarta sección. Dedicaré la última sección a algunas reflexiones sobre la pregunta acerca de la necesidad de una orientación humanista tal como Rüsen la defiende en nuestros días.
Crônicas sobre a Segunda Guerra Mundial: Sílvia de Bittencourt (Majoy) e o lirismo de Seguindo a Primavera
Authors: Ireno Rafael Da Cruz
Published: November 2018

Este artigo discorrerá sobre o livro Seguindo a Primavera (1951), de Sílvia de Bittencourt (Majoy), uma recolha de crônicas escritas durante a Segunda Guerra Mundial. Trata-se, muito provavelmente, da única mulher no grupo de jornalistas do Brasil mandados para a Itália, enviada por uma agência americana para acompanhar o Vº Exército dos Estados Unidos durante o conflito. Aqui, pretendo formalizar e fomentar um debate a respeito desta figura singular, primeiramente, pelo seu quase apagamento completo da bibliografia sobre a participação do Brasil na guerra, em segundo lugar, pelos problemas concernentes à concepção de lirismo que o livro propõe.
Drummond: uma poética entre e por aporias
Authors: Coelho Elisa Domingues
Published: November 2018

A busca pela poesia que escapa à escrita, tema de tantos poemas de Carlos Drummond de Andrade, revela não ser apenas um tema transversal de sua obra, mas o princípio de funcionamento na mesma, que se cria labirinticamente a partir da reflexão sobre o caos moderno. Sua poética, portanto, não é uma lírica do cotidiano, que retira do mais ordinário acontecimento a poesia da vida, como a de Manuel Bandeira, ela vive da incompreensão e da aparente insolubilidade do presente caótico e desumano. A partir da análise feita por Antonio Candido em “Inquietudes na Poesia de Drummond” e Davi Arrigucci Júnior em Coração Partido, vemos como a obra do poeta se movimenta entre os impasses da própria literatura no mundo moderno. Se é a expressão da sua incompreensão e perplexidade diante dos acontecimentos, é também uma preocupação de responder ao tempo presente, como expresso por Mário de Andrade em “O movimento modernista”. É, então, uma lírica que se cria tal qual o Áporo, debatendo-se entre impasses, fazendo do bloqueio seu princípio poético e é na insolubilidade, na ausência de qualquer esperança que o inseto se metamorfoseia em flor e o caos se faz poesia.
Crises, desejos e formas: as faces da resistência na poesia de Max Martins
Authors: Santos Elizier Araujo , Guimarães Mayara Ribeiro
Published: November 2018

É possível considerar a poesia como um ato político de resistência? Seria a poesia, ela própria, um canal de imanente insubordinação? Tais questões nos levam a pensar, neste artigo, em um dos aspectos fulcrais da poesia de Max Martins: a abertura para uma postura crítica do poético. Assim, busca-se refletir sobre certo predicado de resistência que habita o pensamento do poeta paraense, nas faces constituintes de uma transgressão particular vinculada às acepções de metalinguagem, erotismo, visualidade e misticismo que encontramos em sua poesia. Neste percurso interpretativo, apoiamo- nos nos textos de Bosi (1977), Nunes (1992), Siscar (2010) e Barthes (2013), a fim de trazer à luz as crises, os desejos e as formas que conduziram Max Martins, da modernidade ao pensamento contemporâneo, às potências dos atravessamentos poéticos.
Biografia
Authors: Melo Tarso Menezes de
Published: November 2018

Poema para Marielle Franco
Poemas
Authors: Gale Pedro Fernandes
Published: November 2018

Poemas
The enigma of the genus Stenaphorura Absolon, 1900 (Collembola, Tullbergiinae)
Authors: RUSEK JOSEF
Published: November 2018

Stenaphorura japygiformis Absolon, 1900 was redescribed based on the holotype and on virtually topotypic material from the Moravian Karst, Czech Republic. Lectotype of Stenaphorura lubbocki Bagnall, 1935 was redescribed and used for comparison with S. japygiformis. The postantennal organ, composed of 50–56 simple vesicles, is 3.8 times the length of the frontal pseudocellus in S. japygiformis, compared to 75 vesicles and 6.3 times in the related S. lubbocki. Figures and measurements of some structures are given for the first time. As a consequence of my studies Stenaphorurella Luciáñez & Simón, 1992 is sunk into synonymy of Stenaphorura Absolon, 1900. All species transferred into Stenaphorurella by Luciáñez & Simón (1992) and by Khanislamova et al. (1997) are reintroduced into Stenaphorura Absolon, 1900.
A new species of the Rhinella margaritifera group (Anura: Bufonidae) from Brazilian Pantanal
Authors: ÁVILA ROBSON W. , PANSONATO ANDRÉ , STRÜSSMANN CHRISTINE
Published: November 2018

We describe adult morphology, advertisement call and some natural history traits of a new species of toad from the Pantanal, western Brazil. Rhinella paraguayensis sp. nov. belongs to the Rhinella margaritifera group, and is characterized by medium size, snout rounded in dorsal view, with a vertical apical ridge, supraorbital crests weakly developed, parietal crest not well developed, postorbital crest prominent, presence of a dorsolateral line of tubercles, tympanum evident, bony protrusions at angle of jaws, absence of vertebral apophyses and of projections on upper eyelids, and parotoid glands small. The new species is distinguished from other species of the group by geographic distribution and by the use of floating mats of vegetation as reproductive site.
Earthworm fauna of Eastern Taiwan, with descriptions of two new species (Oligochaeta: Megascolecidae)
Authors: WANG YU-HSI , SHIH HSI-TE
Published: November 2018

The earthworm fauna of eastern Taiwan was studied, and two new species, viz. Amynthas shinjiroi sp. nov. and Pithemera tao sp. nov. are described. Other species from our collection included Dichogaster (Diplothecodrilus) saliens (Beddard, 1893), Amynthas aspergillum (Perrier, 1872), A. gracilis (Kinberg, 1867), A. aff. hupeiensis (Michaelsen, 1891), A. robustus (Perrier, 1872), A. aff. morrisi (Beddard, 1892), Pithemera bicincta (Perrier, 1875), P. lanyuensis Shen & Tsai, 2002, and Pontoscolex corethrurus (Müller, 1856). Pithemera lanyuensis was first collected on Lanyu (Orchid Island), but its distribution is now extended to the main island of Taiwan. The finding of the exotic Pontoscolex corethrurus in eastern Taiwan shows it has probably invaded the entire island of Taiwan, and its impacts upon the ecology and agriculture need to be studied in the future.
Revision of the Neotropical subfamily Eurychoromyiinae(Diptera: Lauxaniidae)
Authors: GAIMARI STEPHEN D. , SILVA VERA C.
Published: November 2018

The status of the enigmatic family Eurychoromyiidae is revised to a subfamily of Lauxaniidae, and the entire subfamily is revised with a key to genera and species, and maps for all species. Previously monotypic with only the species Eurychoromyia mallea Hendel, one closely related genus, Tauridion Papp & Silva, is moved into this subfamily, and five new genera are described: Choryeuromyia, Euryhendelimyia, Eurystratiomyia, Physegeniopsis, and Roryeuchomyia. Besides the type species for Eurychoromyia and Tauridion, all species herein are new, including Choryeuromyia xenisma (type species of genus), Euryhendelimyia schlingeri (type species of genus), Eurystratiomyia epacrovitta, Eurystratiomyia erwini (type species of genus), Physegeniopsis albeto, Physegeniopsis ankhoidea (type species of genus), Physegeniopsis hadrocara, and Roryeuchomyia tigrina (type species of genus). Eggs are described for Tauridion shewelli and Physegeniopsis albeto.
Description of a new species of Aeglidae, and new records of related species from river basins in Argentina (Crustacea, Anomura)
Authors: BOND-BUCKUP GEORGINA , JARA CARLOS G. , BUCKUP LUDWIG , BUENO ALESSANDRA A. P. , PÉREZ-LOSADA MARCOS , CRANDALL KEITH A.
Published: November 2018

The anomuran crustacean Aegla saltensis new species, from the Province of Salta in northwest Argentina is described and illustrated, and its morphological differences from other related species are discussed. The 13 species that occur in Argentina are analyzed in the light of new available samples. The geographical distributions of the species are updated and new localities are recorded for eight of the thirteen species.
First record of the sea anemone Nematostella vectensis (Actiniaria: Edwardsiidae) in Southern Hemisphere waters
Authors: SILVA JANINE F. , LIMA CARLOS A. C. , PEREZ CARLOS D. , GOMES PAULA B.
Published: November 2018

This is the first record of the starlet sea anemone, Nematostella vectensis Stephenson, 1935, in Southern Hemisphere waters. Specimens of N. vectensis were collected in the surroundings of the Port of Recife, Pernambuco, Brazil. The species is native to the Atlantic coast of the United States of America; populations along the Pacific coast of the USA and the coasts of England are the result of anthropogenic introduction, probably associated with ships and boats used in oyster commerce (Sheader et al. 1997; Pearson et al. 2002; Reitzel et al. 2008). The present study extends the latitudinal distribution of this species, and we discuss the presence on the Brazilian coast of this exotic species.
First record of the male of Leusaba philippina Stål (Hemiptera: Fulgoromorpha: Tropiduchidae) with a redescription of the genus and species
Authors: WANG RONG-RONG , WEBB MICHAEL D. , LIANG AI-PING
Published: November 2018

The male of Leusaba philippina Stål (Philippines) is recorded for the first time. Redescriptions of the genus and species based on the newly found male and other specimens are provided. Taxonomic notes on the remaining species of the genus, L. marginalis Walker (Borneo), L. rufitarsis (Kirby) (Sri Lanka) and two un-named species are given.