bluuebunny/crossref_metadata_2025 huggingface dataset:
RESPUESTA FISIOLÓGICA DE ESTEVIA (Stevia rebaudiana) CON FERTILIZACIÓN QUÍMICA Y ORGÁNICA
Authors: Castañeda-Saucedo Ma. Claudia , Jiménez-Negrete Cinthia Monserrat , Tapia-Campos Ernesto , Ramírez-Anaya Jessica del Pilar , Iniestra-González J. Jesús , Córdoba-Albores Liliana Carolina
Published: June 2024

La estevia (Stevia rebaudiana Bertoni) es un endulzante no calórico natural, es más dulce que el azúcar de caña de 15 a 30 o de 200 a 300 veces en hoja y extracto, respectivamente. El objetivo del presente estudio fue evaluar el crecimiento y desarrollo de estevia con fertilización química y orgánica. Se estableció un experimento bajo un diseño experimental de bloques completos al azar con siete tratamientos y el testigo: T1 (humus 400 g/planta), T2 (gallinaza 300 g/planta), T3 químico (180N-60P-92K), T4 (humus + gallinaza), T5 (humus + químico), T6 (gallinaza + químico), T7 (humus + gallinaza + químico) y el testigo (sin fertilizar). Se realizaron cuatro muestreos, a los 35, 57, 79 y 99 días después del trasplante (ddt), en cada muestro se evaluó la longitud de raíz (LR), altura de planta (AP), área foliar (AF), peso seco de raíces (PSr), tallos (PSt), hojas (PSh) y total (PSTo); además, se calculó la tasa de crecimiento relativo (TCR), tasa de asimilación neta (TAN), relación de área foliar (RAF), relación de peso foliar (RPF), área foliar específica (AFE) y coeficiente de partición de biomasa (CPB) de raíz, tallo y hojas. Los resultados muestran que el tratamiento con aplicación de humus produjo la mayor AP (95.1 cm) y LR (33.5 cm) a los 99 y 79 ddt. Los tratamientos humus y gallinaza mostraron el mayor PSr (13.13 y 11.47 g), respectivamente, a los 99 ddt. El mejor tratamiento fue 400 g humus/planta + químico (180N-60P-92K), ya que se obtuvo la mayor AF (4118.7 cm2), PSt (38.4 g) y PSh (44.9 g) a los 99 ddt. En PSTo a los 99ddt todos los tratamientos fueron estadísticamente iguales pero superiores al testigo. No hubo diferencias en TRC y TAN a los 99 ddt. Como conclusión, la fertilización con fuentes individuales de humus y gallinaza generan buenos resultados y éstos se incrementan si se mezclan con fertilización química.
CARACTERIZACIÓN FENOTÍPICA DE GERMOPLASMA ELITE DE FRIJOL PARA RESISTENCIA AL TIZÓN COMÚN
Authors: Hernández-Cruz Fátima Adriana , Cruz-Izquierdo Serafín , Corona-Torres Tarsicio , Sandoval-Islas José Sergio
Published: June 2024

El tizón común es una de las enfermedades más importantes en el cultivo de frijol (Phaseolus vulgaris) en México y a nivel mundial. Esta enfermedad es causada por las bacterias fitopatógenas Xanthomonas axonopodis pv. phaseoli y X. fuscans subsp. fuscans. En el presente estudio se evaluaron 23 poblaciones de frijol (Phaseolus spp.) con diferente origen genético para conocer su respuesta a la enfermedad evaluando el área bajo la curva del progreso de la enfermedad (ABCPE) final de cada una. Se establecieron dos experimentos, en el primero se evaluó la resistencia a las cepas por separado en las variedades Flor de Mayo y Negro Bola; en el segundo experimento se realizó una mezcla de las cepas y se infiltraron en combinación en los 23 genotipos para analizar el ABCPE final. La severidad se evaluó seis veces cada cinco días en todos los ensayos realizados. Los resultados mostraron que la resistencia de la variedad Flor de Mayo a ambas cepas es más estable pero menor que la presentada por la variedad Negro Bola, y que el aislamiento de X. fuscans subsp. fuscans, sin importar el ambiente, fue estadísticamente más agresivo que el de X. axonopodis pv. phaseoli; así mismo, se determinó que el genotipo Mixteco-1 fue el que tuvo una mayor ABCPE, mientras que los genotipos Ejotero (Phaseolus vulgaris L), Tepari (Phaseolus acutifolius A. Gray) y Ayocote morado (Phaseolus coccineus L.) mostraron las menores ABCPE. Conjuntamente se encontraron variaciones de los genotipos dentro y entre los ambientes. Debido a que estos genotipos son de diferente origen genético, se propone piramidar los genes de resistencia que poseen, al planear hibridación en programas de mejoramiento genético y lograr una resistencia horizontal duradera.
FITOQUÍMICA DE LAS GLÓQUIDAS DE TUNA (Opuntia albicarpa SCHEINVAR)
Authors: Marín-Campos Victor M. , Álvarez-Sánchez María E. , Maldonado-Torres Ranferi , López-Romero Rosa M. , García-Osorio Cecilia
Published: June 2024

Las glóquidas de la tuna son un subproducto del proceso de limpieza del fruto que se desecha en bolsas plásticas, lo que genera un impacto ambiental con efecto acumulativo debido a que este material lignocelulósico es de biodegradabilidad baja. Para generar valor agregado a este subproducto agrícola se determinaron las propiedades fitoquímicas de los pigmentos y polisacáridos pécticos en hidrolizados de glóquidas de Opuntia albicarpa Cristalina y Burrona. Los análisis por espectrofotometría mostraron que estas estructuras contienen 16.2 ± 3.4 y 20.6 ± 1.2 mg·100 g-1 de betalaínas totales en Cristalina y Burrona, respectivamente, con predominancia de betacianinas. Los flavonoides totales fueron similares en ambas variedades con 101.3 ± 4.3 mg quercetina 100g-1 en Cristalina y 112.9 ± 6.9 mg·100g-1 en Burrona. La concentración de fenoles totales fue 427.4 ± 18.4 y 385.7 ± 17.0 mg·100g-1 en Burrona y Cristalina, respectivamente. La concentración de pectinas totales, expresada como ácido galacturónico, fue de 128.7 ± 26.7 y 35.6 ± 17.3 mg·100g-1 de muestra en Burrona y Cristalina. La composición de las glóquidas mostró que el subproducto del beneficiado de la tuna tiene potencial de uso nutracéutico y bioestimulante de cultivos agrícolas.
EL MERCADO DE LA MANZANA FRESCA EN MÉXICO: 2000-2021
Authors: Menchaca-Aguilar Abdiel , Mora-Flores José Saturnino , García-Salazar José Alberto , García-Mata Roberto , Escobedo-Garrido José Sergio
Published: June 2024

Debido a su aporte de vitaminas A, C, K y B6, magnesio, hierro y potasio, la manzana es uno de los productos frutícolas de mayor consumo en el mundo. En 2021 se produjeron y consumieron, respectivamente, 632 y 931 mil toneladas de manzana en México, de ahí que el saldo comercial es deficitario. El objetivo de este estudio fue analizar el mercado de la manzana en México para conocer los factores que lo determinan. La metodología consistió en la estimación de un modelo econométrico de ecuaciones simultáneas, que utilizó series de tiempo de 2000 a 2021. La oferta (0.01) y demanda (0.94) resultaron inelásticas a sus precios y el precio internacional se transmite de forma inelástica (0.04) al precio al mayoreo. La temperatura mínima promedio (-1.26), el precio al consumidor (-3.34) y el ingreso nacional disponible (6.09) resultaron elásticos respecto al saldo de comercio exterior. El déficit comercial puede mejorar si aumenta la oferta, pero medidas que influyan en el precio al productor de manzana y del fertilizante serán poco efectivas. Se recomiendan acciones que fomenten inversiones en protección de cultivos ante eventos climáticos desfavorables.
DIVERSIDAD GENÉTICA DE LINÁLOE EN POBLACIONES DEL BOSQUE TROPICAL CADUCIFOLIO EN MÉXICO
Authors: Cruz-Larios Iris Jacaranda , Ramírez-Herrera Carlos , Hernández-Rodríguez Martha , Velasco-García Mario Valerio , Cetina-Alcalá Víctor Manuel , Valdez-Hernández Juan Ignacio
Published: June 2024

La diversidad genética es importante para la adaptación de una especie a los cambios ambientales, por lo que el conocimiento del nivel y distribución de la diversidad es útil para elaborar estrategias de conservación y manejo de una especie; sin embargo, la información sobre diversidad genética es escasa para especies arbóreas que habitan en el bosque tropical caducifolio, como es el caso de lináloe [Bursera linanoe (La Llave) Rzed., Calderón & Medina], una especie que crece en dos subprovincias bióticas en el bosque tropical seco de los estados de Guerrero, Morelos, Puebla y Oaxaca en México. Por lo anterior, el objetivo del presente estudio fue estimar la diversidad y estructura genética de Bursera linanoe en poblaciones naturales en dos subprovincias bióticas. En 2019 se recolectó follaje de 92 árboles de lináloe en cuatro poblaciones en las subprovincias bióticas Balsasana y Cañadiana. Posteriormente, el ADN se extrajo del follaje con el protocolo CTAB. Cinco intermicrosatélites (ISSR) se utilizaron, y los fragmentos fueron separados en geles de agarosa. Los siguientes estimadores de diversidad genética se calcularon: porcentaje de loci polimórficos (P), heterocigosidad esperada (He), número efectivo de alelos por locus (Ne) e índice de Shannon (IS); además, se estimó el FST de Wright y se realizó un análisis de varianza molecular (AMOVA). También, la estructura genética se evaluó con el software STRUCTURE. Los valores de los estimadores de la diversidad genética para lináloe fueron: P = 100 %, He = 0.352, Ne = 1.618 e IS = 0.522, el valor de FST fue 0.160. La partición de la diversidad genética fue de 74 % dentro de poblaciones, 21 % entre poblaciones y 5 % entre subprovincias. Cuatro grupos (K) se formaron con los árboles de lináloe de las cuatro poblaciones. El número de migrantes fue 1.3 por generación. Se encontró una diversidad genética alta y una diferenciación alta entre poblaciones de Bursera linanoe.
DULCE AMANECER, PRIMERA VARIEDAD MEXICANA DE COSMOS CHOCOLATE
Authors: Morales-Vázquez Bulmaro , Colinas-León Ma. Teresa , Mejía-Muñoz José M. , Juárez-Hernandez Ma. Jesús , Martínez-Damián Ma. Teresa , Martínez-Solís Juan
Published: June 2024

Cosmos atrosanguineus (Hook.) Voss, conocido como cosmos chocolate, es una especie de la sección Discopoda del género Cosmos, su uso principal es ornamental por el color guinda y aroma a chocolate de sus flores, es endémica de México y se reportó al límite de la extinción de su medio natural; sin embargo, en años recientes se han localizado pequeñas poblaciones silvestres (Castro-Castro et al., 2014; Gómez-Pedraza et al., 2019).
APORTE DE NITRÓGENO POR EL SUELO Y EFICIENCIA DE APROVECHAMIENTO DEL NITRÓGENO APLICADO EN MAÍZ DE TEMPORAL
Authors: Sánchez-de Jesús Marco A. , Volke-Haller Víctor H. , Cortés-Flores José I. , María-Ramírez Andrés , San-Martín-Hernández César
Published: June 2024

Las variaciones de la eficiencia de aprovechamiento del fertilizante nitrogenado en maíz y la pérdida de nitrógeno (N) al medio ambiente son de gran relevancia en la producción agrícola. El objetivo de esta investigación fue estimar el aporte de N por el suelo y la eficiencia de recuperación del N aplicado en maíz de temporal en suelos de diferente contenido de materia orgánica. Se establecieron dos experimentos en Tetla de la Solidaridad, Tlaxcala (sitios T1 y T2) y uno en Montecillo, Estado de México (sitio M). Los tratamientos fueron: 0, 90 y 120 kg N ha-1 en el sitio T1 y 0, 70 y 100 kg N ha-1 en los sitios T2 y M. El diseño experimental fue bloques completos al azar con cuatro repeticiones en Tetla y tres repeticiones en Montecillo. El análisis de la información fue mediante regresión. El contenido de materia orgánica del suelo fue 1.1, 1.2 y 3.3 %, y de N-NO3 en la siembra de 36, 31 y 72 mg kg-1 en los sitios T1, T2 y M, respectivamente. El aporte de N por suelo franco arenoso fue 117 kg N ha-1 en el sitio T1, 67 kg N ha-1 en el sitio T2 y de 80 kg N ha-1 en el sitio M de suelo franco arcilloso. Las eficiencias de aprovechamiento de N aplicado fueron de 32 a 37 % en el sitio T1, de 4 a 7 % en el sitio T2 y de 0 % en el sitio M. La causa de estas bajas eficiencias se asoció con alta concentración de N-NO3 en los tres sitios, los bajos rendimientos por la siembra tardía en los sitios T2 y M, escasa precipitación en el sitio T2, deficiencia de micronutrientes e infestación de gallina ciega (Phyllophaga spp.) en el sitio M.
Kentsel Yoksulluk Tezlerinin Sosyal Politika Bağlamında İncelenmesi
Authors: Şeker Aziz , Kaya Gazenfer
Published: June 2024

Yoksulluk, insanlığın temel sorunlarının başında gelir. İnsanlık kadar eski bu sorun, eskimemekte ve de çeşitlenerek yeniden üretilmektedir. Yapısal etmenler, ülkelerin içinde bulunduğu yoksulluğun ana belirleyicisidir. Dünya genelinde ciddi düzeylerde açlık ve yoksulluğun var olduğu ve de insanların yaşamlarını sürdürmek için büyük mücadele içinde oldukları bilinmektedir. Kentleşen ve daha da kentleşecek dünyada, kentsel yoksulluk en önemli gerçekliktir. Türkiye’nin son kırk yılına damgasını vuran neoliberal ekonomi politikalar, sosyal, ekonomik ve demografik dengelerin değişimine neden olmuştur. Bu politikaların uygulandığı süreçte hızlanan göç ve kentleşme, hane halklarının yoksulluğunu derinleştirmiştir. Ayrıca Türkiye’ye yönelen milyonlarca uluslararası göçmen, kentlerde yeni yoksul grupları oluşturmuştur. Bu durum kentsel yoksulluğa yönelik akademik ilgiyi artırmıştır. Lisansüstü tezler, bu akademik ilginin görülebileceği bir alandır. Kentsel yoksulluğa ilişkin lisansüstü tezlerdeki saptamalarda ve çözüm önerilerinde, sosyal politika boyutuna nasıl yaklaşıldığı önemlidir. Nitekim kentsel yoksulluğun azaltılmasında, karar vericilerin geliştirdiği, uygulamayı hedeflediği ve de uyguladığı sosyal politikalar oldukça kritiktir. Bu çalışmada sosyal bilimler alanındaki kentsel yoksulluk temalı 23 lisansüstü tez incelenmiştir. Söz konusu tezlerdeki araştırma verileriyle, kentsel yoksulluk ve sosyal politika arasında nasıl bir bağlantı kurulduğuna odaklanılmıştır. Ayrıca tezlerden elde edilen sonuçlar üzerinden kentsel yoksulluk alanında geliştirilecek sosyal politika önerilerine değinilmiştir. Tamamı 2000’li yıllarda geçekleştirilen tezlerde, kentsel yoksulluk ve sosyal politika ilişkisine sınırlı olarak yer verildiğinden, bu ilişkinin kapsamlı araştırmalarla desteklenmesi literatüre önemli katkı sağlayacaktır.
Preliminary study of mosquitoes’ diversity (Diptera: Culicidae) in tree holes in an Atlantic Forest reserve in Rio Grande do Norte, Brazil
Authors: de Melo Silva Marjore Lorena , Moura Barbosa Taciano , de Melo Freire Renato César , Silva-Inacio Cássio Lázaro , Souza e Guimarães Ricardo José de Paula , Antonaci Gama Renata
Published: June 2024

This study aimed to do a short and single survey of the diversity of mosquitoes found in tree holes within a fragment of Atlantic Forest in Rio Grande do Norte, Brazil. Larvae were collected through active search, inspecting tree cavities and collecting water and larvae using a homemade siphon on a single day. Eight species of Culicidae were recorded from the surveyed tree holes. Haemagogus leucocelaenus (Dyar & Shannon, 1924) and Haemagogus janthinomys Dyar, 1921 were the most abundant species, accounting for 63.1% of the total specimens collected, followed by Culex (Microculex) sp. (12.20%), Aedes terrens (Walker, 1856) (5.26%) and Aedes fulvithorax (Lutz, 1904) (1.75 %). Although there are other breeding sites in nature (bromeliads and bamboos), tree holes in native trees play a fundamental role in maintaining and conserving the culicid fauna due to their water storage capacity, especially in wild species, such as species of the genus Haemagogus Williston, 1896.
Tarántulas chilenas de la subfamilia Theraphosinae (Mygalomorphae: Theraphosidae): una revisión a nivel de género
Authors: Montenegro V. Rubén , Aguilera Milenko A.
Published: June 2024

En el presente trabajo se realiza una revisión taxonómica de los géneros de Theraphosinae presentes en Chile, además de una clave que facilite su reconocimiento. Adicionalmente, se ofrece para cada uno de ellos una descripción general y una diagnosis actualizada, además de tratar algunos aspectos sobre el estado de conservación, historia natural y distribución geográfica de algunas de sus especies.
AĞ TOPLUMUNDA POST-DEMOKRATİK GÖZETİM, MİLLÎ KİMLİK, VATANDAŞLIK VE EGEMENLİK İLİŞKİSİ
Authors: Şimşek Serpil Seda
Published: June 2024

Küreselleşmenin ulus devletlerin sonunu getirmediğinin anlaşılmasının ardından, ağ toplumunda ulus devletlerin, dijital alanda, egemenliklerini yeniden inşa etme ihtiyacı belirmiştir. ABD yönetiminin kendi vatandaşlarını ve sınırlarından binlerce kilometre uzakta yaşayan başka ülkelerin vatandaşlarını kitlesel olarak gözetlediğini ortaya çıkaran Ulusal Güvenlik Ajansı (NSA) skandalı, iletişim ağlarının ve teknolojilerinin küreselleşmesi ya da millîleştirilmesi ve kamulaştırılması tartışmalarını beraberinde getirmiştir. Devletlerin küresel ağ sisteminde geri dönüşü, ulus devletlerin, sadece yasal düzenlemeler ve mevzuatlarla değil, bilgi teknolojisi yaratmadaki rolü açısından da yeni tanımlamalar getirilmesi zorunluluğu doğurmaktadır. Bu yeni ağ toplumu düzeniyle birlikte post-demokrasinin yükselmesinin de güçlü bir ihtimal olarak ortaya çıktığı söylenebilir. Bu çalışmada, post-demokrasilerde, post-demokratik gözetim, millî kimlik, vatandaşlık ve egemenlik ilişkisinin nasıl şekilleneceği sorusunun cevabı aranmaktadır. Crouch, Rancière, Rorty, Wolin, Habermas ve Mouffe tarafından öne sürülen post-demokrasi kavramı açıklanarak, ağ toplumunda post-demokratik gözetim, millî kimlik, vatandaşlık ve egemenlik ilişkisinin dönüşümüne odaklanılmaktadır. Post-demokratik gözetim, millî kimlik, vatandaşlık ve egemenlik ilişkisiyle ilgili bir teorik çerçeve sunularak, literatüre katkıda bulunulmaktadır.
Constructing Lyapunov–Krasovskii functionals for some classes of switched positive systems with infinite delay
Authors: Aleksandrov Alexander
Published: June 2024

The problem of absolute stability is investigated for a switched positive Persidskii system with infinite delay. With the aid of a special construction of Lyapunov–Krasovskii functional, sufficient conditions of absolute stability are derived. These conditions are formulated in terms of the existence of a positive solution for an auxiliary system of linear algebraic inequalities. It is shown that a similar construction of Lyapunov–Krasovskii functional can be used for the permanence analysis for a Lotka–Volterra model of popolation dynamics.
Combined repetitive control system for active damping of forced vibrations
Authors: Shelenok Evgeniy
Published: June 2024

The consideration was given to the damping of periodic vibrations acting on vibration protected plant using a hydraulic support with active control. A nonlinear robust-adaptive repetitive control system was synthesized for the technical plant under consideration. The author uses a piezoelectric accelerometer to measure acting vibrations, the generator for periodic signals to compensate for repetitive force action and the hyperstability criterion to synthesize a control algorithm. In the final section it was present a computational experiment whose results clearly illustrate the quality of the obtained control system.
The relationship between the level of physical activity and lung function
Authors: Djajasasmita Daswara , Y Triningtyas Anastasia , Afrila Syafarina
Published: June 2024

Physical activity is part of the basic needs of daily life, especially to improve the quality of health. Engaging in physical activity can increase blood flow through the lungs, causing oxygen to diffuse into the pulmonary capillaries with a larger or maximum volume. The purpose of the study was to determine the relationship between the level of physical activity and lung function. This study is a cross-sectional analytic study with a sampling technique of consecutive sampling, using a sample of 60 students of the Faculty of Medicine, Universitas Jenderal Achmad Yani who meet the inclusion and exclusion criteria. Research data were obtained using the International Physical Activity Questionnaire (IPAQ)-lf questionnaire instrument to assess physical activity levels and a vitalograph spirometer to assess FVC, FEV1 and FEV1/FVC. Data were analyzed using the Spearmann Rho Correlation Test. The results showed that there was a significant relationship between physical activity level and FVC% (p=0.008 and r=0.399) and FEV1% (p=0.000 and r=0.501), while there was no significant relationship between physical activity level and FEV1/FVC ratio (p=0.071 and r=0.235). Although there was no significant relationship between physical activity level and FEV1/FVC ratio, there was a positive and unidirectional relationship between physical activity level and all lung function parameters in this study. Physical activity is one factor that has a positive influence on the respiratory system.When done regularly there will be adaptation to the body by increasing ventilation for maximum oxygen uptake and better diffusion capacity, resulting in respiratory efficiency. Therefore, students are expected to do physical activity according to recommendations to achieve health benefits, including increasing lung function parameters such as FVC, FEV1 and FEV1/ FVC ratio.
The relationship between menstrual cycle and psychological stress on acne vulgaris incidence
Authors: K P Dewi Ania , Munirah B Rina , Rahman H Westinawati
Published: June 2024

Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit and presents with a polymorphic clinical picture such as comedones, papules, pustules, nodules, and scars. AV is often experienced by both women and men, affecting 85% of young adults aged 12-25 years, with women more commonly affected than men. There are several triggers that contribute to the onset of AV, including the menstrual cycle and psychological stress. This study aims to determine the relationship between the menstrual cycle, psychological stress, and the occurrence of acne vulgaris in female medical students at Universitas Jenderal Achmad Yani. The research design uses a cross-sectional study approach. There were 48 people who met the inclusion criteria. Respondents in this study were asked to fill out informed consent forms, questionnaires, and indicate their availability for standardized facial photos. The results of this study obtained a p-value of 1.000 and 0.529 (p-value > 0.05). It was found that there is no statistically significant association observed between either regular menstrual cycles or severe psychological stress and the presence of acne vulgaris in this sample. The odds ratios for both variables (1.052 and 1.303) suggest minor increases in the odds of acne vulgaris presence, but they do not reach statistical significance. This relates to the occurrence of acne vulgaris, which is not only caused by factors such as the menstrual cycle and psychological stress but also by various triggering factors including diet, use of cosmetics, facial hygiene, and unhealthy sleep patterns.
SKIN-LIMITED VASCULITIS
Authors: Maksimovich ВV.O. , S.A. S.A. , Lamotkin I.A. , Ilyina I.V. , Gladko O.V.
Published: June 2024

The article considers the classification of cutaneous vasculitis, the main clinical manifestations, differential diagnostics and treatment principles.
SOME ISSUES OF FORENSIC AND CRIMINALISTIC RESEARCH OF GENERAL AND SPECIAL SIGNS IN TRACES OF A SHOT FROM A 12-GAUGE HUNTING WEAPON USING A CARTRIDGE EQUIPPED WITH A WAD-CONTAINER AT A DISTANCE OF 100 CM
Authors: Kataev A.S. , Suvorov A.S. , Belavin A.V. , Einstein V.K.
Published: June 2024

The article deals with the issues of forensic and criminalistic research of the traces of a bullet and additional factors of the shot, formed on the obstacle from firing with a 12-gauge hunting weapon equipped with a polymer wad-container at a distance of 100 cm.
THE USE OF CPAP THERAPY IN THE MEDICAL REHABILITATION OF PATIENTS WITH CORONARY HEART DISEASE WITH OBSTRUCTIVE SLEEP APNEA SYNDROME AFTER CORONARY ANGIOPLASTY
Authors: Yudin V.E. , Klimko V.V. , Shchegolkov A.M. , Kalinina S.V. , Chursina T.V.
Published: June 2024

The article analyzes the diagnostic results of 245 patients with coronary heart disease after coronary angioplasty. Obstructive sleep apnea was detected in 35.7% of patients. According to the rehabilitation programs, the patients were divided into two groups of 30 people in each one, comparable in age, severity of coronary artery disease, number of surgical interventions, severity of OSA and pharmaseutical treatment. The patients of the main group were prescribed CPAP therapy along with the standard therapy. The effectiveness of CPAP therapy use in the medical rehabilitation of patients with ischemic heart disease with OSA syndrome after coronary angioplasty has been studied. The inclusion of the technique in the comprehensive program of medical rehabilitation in this category leads to a decrease in the number of complaints, improvement of the functional and psychological state, stabilization of the cardiorespiratory system and increased tolerance to physical activity.
CHALLENGES IN DIAGNOSING SPLENIC ABSCESSES IN HIV-INFECTED PATIENTS
Authors: Puchkov S.S. , Faller A.P.
Published: June 2024

Objective: Improve the quality of treatment for HIV-infected patients with heart attacks and splenic abscesses by optimizing the diagnosis of these pathological processes. Material and Methods: From 2004 to 2019, 14,405 HIV-infected patients, including 34 patients with suspected splenic abscesses, were treated in the surgical department of the Infectious Clinical Hospital State Budgetary Healthcare Institution (ICH SBHI) No.2. The average age was 34.9 years, 22 males and 12 females. Three patients had stage 3, ten people had stage 4A, ten patiens had stage 4B, and eleven people had stage 4B HIV infection. Patient management followed the generally approved algorithms of the Ministry of Health of the Russian Federation for surgical patients (taking into account the HIV-infection co-morbidity). The following was done: complaints and anamnesis were collected, the duration of HIV-infection, adherence to ART, presence of opportunistic and concomitant diseases were carefully determined, an abdominal ultrasound imaging and an abdominal CT scan were performed. Four patients were diagnosed with splenic infarction; they were treated conservatively and discharged in a satisfactory condition. Surgical treatment was performed in 30 out of 34 patients in the period from 1 to 57 days from admission to the hospital, usually on day 9. 26 of them were discharged and 4 patients died. All 30 surgical patients received antibiotic therapy, surgical material was examined histologically, the cause of the splenic process was determined and therapy was adjusted (if tuberculosis had been diagnosed, patients were moved to an anti-TB hospital, if lymphoma had been diagnosed, patients were moved to an oncohematology department). Results: When examining HIV-infected patients with complaints of abdominal pain and hyperthermia, a detailed history of HIV infection, adherence to ART, viral load and immune status (if the patient knows these data), the presence of concomitant pathological conditions should always be clarified, as wells as abdominal ultrasound and abdominal CT scan should be performed as early as possible. All surgical materials should be examined histologically to verify the cause of the splenic process. Patients in stages 4B-4B, not adhering to ART, with a high viral load and low immune status, suffering from drug addiction and HCV infection, more often get complicated forms of the disease.
GYNECOMASTIA: THE RELATION OF PATIENT COMPLAINTS, TYPE OF CONSTITUTION AND CLINICAL TYPE OF A DISEASE
Authors: Pakhomova R. A. , Sergeev D. I. , Drobiazgo S. V. , Maslovskiy A. S.
Published: June 2024

The article provides a brief literature review of the problem of gynecomastia, diagnostics and treatment of this disease, the relation between the frequency of detection of gynecomastia and oncological processes in the breast. It has been shown that gynecomastia is detected in male patients of different age groups, different in BMI, body type. The correlation of complaints and body type in patients with gynecomastia is shown, as well as the connection of clinical types of gynecomastia which depend on the patient's constitution. The article discribes the necessity of further studies of the relation between gynecomastia and body types in order to find the optimal surgical treatment for this problem.
SOME SAFETY ORGANIZING ISSUES OF MEDICAL AND OTHER WORKERS WHILE PERFORMING EMPLOYMENT DUTIES AT THE SCENE OF A RAILWAY EMERGENCY
Authors: Kataev A.S. , Suvorov A.S. , Belavin A.V.
Published: June 2024

The article examines the issue of a potential danger to the life and health of all participants of the emergency liquidation in railway transport, and also suggests an algorithm for cooperative actions.
ORGANIZING OF MEDICAL WASTE MANAGEMENT IN A PEDIATRIC EMERGENCY MEDICAL ORGANIZATION
Authors: Gladko V.V. , Maev E.Z. , Vlasenko A.V. , Samokhina N.Yu.
Published: June 2024

Relevance. All over the world environmental protection issues are taken into great consideration. A serious threat of environmental pollution exists from medical waste in case of improper organization of their collection, movement, disinfection, transportation and disposal. The requirements set out in the sanitary rules and regulations for the management of medical waste are not fully understood by the responsible people and require clarifications and commentary. Objective. Determination of the organizing features of medical waste in a medical organization of an emergency pediatric profile. Summary. Strict organizing rules following of medical waste management in a medical organization plays an important role in the prevention of infections associated with medical care provision and allows to fully avoid nosocomial infection for both patients and employees of a medical organization. To carry out the correct collection, accounting, movement, disinfection and transportation of medical waste, a number of administrative, organizational and anti-epidemic measures need to be done in a medical organization.
EFFICACY OF ULTRASOUND-GUIDED TRANSPERINEAL BOTULINUM TOXIN INJECTIONS FOR THE DETRUSOR-SPHINCTER DYSSYNERGIA TREATMENT
Authors: Salyukov R.V. , Pavlov A.Yu. , Kotlyarov P.M. , Tsallagova Z.S. , Kasatonova E.V.
Published: June 2024

Transurethral botulinum toxin type A (BT) injections to the external urethral sphincter are the most effective and safe method of treating detrusor-sphincter dyssynergia (DSD) in patients with a spinal cord injury. The technique requires special logistics and anesthetic support and is difficult to reproduce in the conditions of rehabilitation centers. This article presents comparative data on the treatment of detrusor-sphincter dyssynergy with injections of botulinum toxin type A into the men external urethral sphincter with minimally invasive transperineal administration under ultrasound guidance (main group, N = 36) and transurethral administration (control group, N = 41). Evaluation of the treatment results of patients in both groups showed that the incidence of postoperative complications was significantly lower in patients of the main group (11.1% and 53.7%, respectively, p < 0.05) with a shorter duration of intervention (26 and 42 minutes, respectively, p < 0.05). There were no statistically significant differences in the incidence of autonomic dysreflexia and urodynamic parameters after 3 and 6 months of follow-up. The clinical effect with the transperineal technique was achieved in 55.6% by the 3rd month after injection, and in 66.7% of men by the 6th month after the treatment, with an expected decrease in efficiency to 35.7% by 12 months of observation. Transperineal injections of BT into the zone of the external urethral sphincter in the treatment of DSD in patients with traumatic spinal cord disease are comparable in their effectiveness to transurethral endoscopic administration of BT, however, it is accompanied by a lower incidence of perioperative complications.
THE USE OF THE COMBINED METHOD OF MICRONEEDLING AND RADIOFREQUENCY THERAPY AND DERMAL FILLERS FOR ATROPHIC SCARS TREATMENT IN THE FACIAL AREA IN THE CONTEXT OF POST-ACNE SYNDROME
Authors: Gladko V. V. , Izmaylova I. V.
Published: June 2024

The article describes the study of the effectiveness of aesthetic correction of atrophic scars in the facial area caused by postacne syndrome using a combined method of fractionated radiofrequency therapy and microneedling, and then injecting the intradermal hyaluronic acid fillers using the microbolus method.
METHODOLOGICAL PRINCIPLES OF MEDICAL REHABILITATION OF PATIENTS WITH VISUALLY STRENUOUS WORK WITH THE SYMPTOMS OF ACCOMMODATIVE ASTHENOPIA AFTER EXCIMER LASERCORRECTION OF MYOPIA
Authors: Yudin V. E. , Yaroshenko V. P. , Belikova E. I. , Gatilov D. V. , Ovechkin I. G. , Kosukhin E. S.
Published: June 2024

Background. The main functional disorder of the visual system during long work with a personal computer is accommodative asthenopia (AA), which is reflected in subjective and objective symptoms. Aim. Scientific substantiation, development and evaluation of the clinical effectiveness of medical rehabilitation (MR) of patients with visually stressful work with AA phenomena. Materials and methods. The study was performed with the participation of 162 patients with visually stressful work (average age 28.2±1.3 years) with AA 3–4 months after excimer laser correction of myopia (LASIK method). MR was performed according to the newly developed and traditional methods. Examination of the state of vision was carried out according to the diagnostic criteria of AA. Results. A statistically higher (compared to traditional) clinical efficacy of the newly developed MR technique was established, which is confirmed by the achievement of normative indicators of objective accommodation and subjective status after rehabilitation treatment. Conclusions. MR for patients with AA must be carried out in accordance with the new methodological principles (personalization, complexity, consistency, standardization, repeatability), the main of which is personalization based on the diagnosis and adequate treatment of the form of AA.
TREATMENT AND MEDICAL REHABILITATION OF PATIENTS WITH VARICOSE VEINS OF THE LOWER LIMBS USING MODERN PHYSICAL METHODS
Authors: Dudarev V. V. , Yudin V. E. , Shchegolkov A. M. , Klimko V. V. , Kalinina S. V. , Chursina T. V.
Published: June 2024

Background. The urgency of the problem of chronic venous insufficiency (CVI) with trophic disorders dictates the need to find new approaches to the treatment and medical rehabilitation of patients. Purpose. To study the results of treatment and medical rehabilitation of patients with varicose veins and post-thrombophlebitic syndrome using endovenous radiofrequency ablation of subcutaneous and perforant veins and the use of air-plasma streams of nitrogen monoxide. Materials and methods.178 procedures were performed using modern physical methods: radiofrequency ablation of veins, including 41 procedures for radiofrequency ablation of failed perforant veins in patients with postthrombophlebitic syndrome with chronic venous insufficiency of the III degree, C5-C6 according to CEAR. The use of air-plasma streams of nitrogen monoxide in the treatment of trophic ulcers of the lower extremities of venous etiology in 29 patients was studied. Results. Endovenous radiofrequency ablations are highly effective, minimally invasive methods of treatment and rehabilitation, with good results of regression of CVI symptoms, easily tolerated by patients, providing short periods of rehabilitation of patients and restoration of their working capacity. Conclusions. Medical rehabilitation of patients using plasma flows (NO) leads to an improvement in the state of microcirculation in the tissues of the lower extremities in the form of an increase in the rate of tissue blood flow, a decrease in venous congestion, accelerated repair of ulcerative defects due to accelerated proliferation of endothelial cells and neoangiogenesis.
INVESTMENT AND LEGAL ASPECTS OF BIOTECHNOLOGY DEVELOPMENT
Authors: Gladko V. V. , Ikonnikov D. G. , Maev E. Z. , Zubritsky V. F. , Pilyus E. V. , Lapteva E. A. , Zubritsky D. V.
Published: June 2024

The article is devoted to the development of mechanisms of public-private partnership in implementing investment projects in healthcare the conditions of limited financing opportunities. The authors conducted an analysis of the healthcare market, evaluated the use of various biotechnological methods in healthcare, agriculture, and food production. The need for regulation of biotechnological research and further development of the regulatory the regulatory framework was justified. An investment project was proposed addressing the development and use of functional nutrition obtained by the bioconversion methods in the rehabilitation process.
INFLUENCE OF ANGELICA AMURENSIS EXTRACTS ON THE CYTOKINE SYNTHESIS IN VITRO
Authors: Volchek I. A. , Teryaev A. S.
Published: June 2024

Background. Background. An imbalance in the ratio of cytokines underlies the pathogenesis of many diseases and pathological processes. Modern pharmacological agents, obtained by chemical synthesis or biotechnologically, in some cases are inferior to substances of natural origin. The main advantages of the latter over synthetic analogues are their relatively low toxicity to the body, the similarity of the chemical structure of natural compounds and physiologically active human substances, which greatly accelerates the inclusion of drugs in biochemical processes. Therefore, the attention of researchers was again attracted by traditional medicine, in particular, preparations of plants of the genus Angelica of the family Apiaceae (Umbelliferae). Aim. To conduct a comparative study of the cytokine-modulating effect of Angelica amurensis extracts obtained by different methods. Materials and methods. Roots and grass of Angelica аmur (Angelica amurensis) were used as feedstock. The following methods were used to extract the material: water-alcohol extraction in a circulating Soxhlet extractor; submersible ultrasonic extraction in а water-alcohol solution; accelerated extraction with ethanol ASE (Accelerated solvent extraction). To determine the cytokine-modulating effect of Angelica amurensis extracts obtained by various methods, we studied the synthesis of GM-CSF, IFNγ, IL-2, IL-4, IL-6, IL-8, IL-10, TNFα by peripheral blood mononuclear cells of healthy donors. Results. It has been established that preparations of Angelica amurensis have an pronounced effect on the synthesis of cytokines by human mononuclear cells. In this case, the direction of action significantly depends on the extraction method, which determines the composition and ratio of inhibitory and/or stimulating components. Conclusions.The research results indicate the prospects and expediency of developing methods for creating new pharmaceutical substances and compositions based on extracts of plants of the genus Angelica, applicable in medicine, veterinary medicine as biologically active additives and, in cosmetology.
ALCOHOL ABUSE IN WAR VETERANS TREATED IN A PSYCHIATRIC HOSPITAL
Authors: Reznik A.M.
Published: June 2024

Background. The high prevalence of alcohol abuse and alcohol dependence, comorbidity with other mental disorders, and unclear causal attribution of alcohol use disorders in Russian veterans of local wars became the background for this study. Purpose. To study the prevalence of alcohol addiction in veterans among Russian veterans of local wars who underwent inpatient treatment, to check the significance of combat stress factors for the development of alcohol dependence, to study the relationship between alcohol dependence and alcohol abuse with symptoms of stress disorders. Methods. The observational case-control study included 685 patients who were treated in the psychiatric departments of military hospital: 264 veterans of military conflicts who received inpatient treatment at the hospital from 1992 to 2010 (the main group); 296 people, all military personnel and retirees who received treatment in the hospital during one calendar year, who had never participated in combat operations in the past (the 1st comparison group); 125 servicemen (regular and reserve) who did not take part in hostilities and matched the average age and age distribution curve of the patients of the main group (the 2nd comparison group). In the compared samples, a clinical and psychopathological analysis of the symptoms identified in patients was carried out, followed by the application of the ICD-10 criteria for diagnosing post-traumatic stress disorder (PTSD) and alcohol use disorders, which made it possible at the stage of data analysis to establish the significance of the difference in their frequency and degree of association. Results and conclusion. There was no difference in the prevalence of alcohol dependence and alcohol abuse symptoms among veterans and other servicemen and military retirees who did not take part in hostilities. At the same time, there was a tendency to underdiagnose alcohol dependence in veterans in general and those with PTSD symptoms in particular. In other words, the diagnosis of alcohol dependence was not made in most cases when veterans showed symptoms of stress or other mental disorders along with signs of alcoholism. These cases were more likely to be diagnosed as having a stress-related mental disorder or other mental disorder, with alcohol abuse being characterised as co-occurring or complicating. In the sample of veterans, there was no significant relationship between any forms of addictive behavior and the presence of symptoms of stress disorders. On the contrary, the symptoms of re-experiencing trauma were more often observed in veterans who were not prone to frequent drinking. Combat stressors traceable in the anamnesis did not differ in their occurrence in veterans with any form of alcohol abuse and veterans who are not prone to frequent alcohol use. A slight difference was noted only in the fact that among the pathological reactions in combat situations among veterans abusing alcohol, addictive behavior was more often traced and, therefore, alcohol abuse during combat requires additional testing for its prognostic value.
CLINICAL EXPERIENCE OF USING ANGELICA DAHURICA FOR ANDROGENIC ALOPECIA
Authors: Volchek I.A. , Teryaev A.S. , Safonova L.A.
Published: June 2024

Background. Androgenic alopecia is an important problem of dermatology and cosmetology. The search for new approaches, means and methods of prevention and treatment of this condition is constantly ongoing. One of the promising directions is the use of traditional Chinese medicine, in particular, plants of the genus Angelica. Purpose. To evaluate the clinical efficacy of a cosmetic product containing Angelica Dahurica extract for androgenic alopecia. Materials and methods. From the roots and herbs of Angelica Dahuricа, an extract and then a hair serum with 5% extract content were produced according to the exclusive author's technology of "Research Center for Immunology and Allergology", Ltd. in accordance with GOST 31679-2012 "Cosmetic liquid products. General technical conditions". To assess the clinical efficacy of the product, 15 volunteers suffering from androgenic alopecia with 3-5 Norwood stage aged from 38 to 62 years were examined. The study was conducted for 6 months. The serum was applied to the scalp 1 time a day for 6 months. Results. All patients experienced a reduction in f hair loss and an increase in hair growth rate, a significant improvement in hair quality. In 9 patients (60%), there was an improvement in the condition of the scalp skin. This was evidenced by a decrease in the level of peeling and increased oiliness, as well as skin sensitivity. Conclusions. The created serum based on Angelica Dahurica extract is effective in the treatment of androgenic alopecia. Preparations of the Angelica Dahurica, as well as other plants of the genus Angelica, are promising for use in trichological practice.
TRANSNASAL ENDOSCOPIC REMOVAL OF A SINONASAL AND SKULL BASE JUVENILE OSSIFYING FIBROMA IN A CHILD
Authors: Grachev N.S. , Vorozhtsov I.N. , Gorozhanina A.I.
Published: June 2024

This article describes a clinical case of a 10-year-old patient with juvenile ossifying "broma of the nasal cavity, paranasal sinuses and skull base, with orbital compression. The patient underwent transnasal endoscopic tumor removal. After 12 months, revision endoscopic intervention was performed due to recurrence of the disease. After surgical treatment, the patient had no evidence of recurrence or continued growth of the neoplasm during the 3-year follow-up period. The article presents the results of the visualization methods of examination at the pre- and postoperative stages.
USE OF A RELOCATED ETHMOID ARTERY FLAP IN THE SURGICAL TREATMENT OF NASAL SEPTUM PERFORATIONS
Authors: Shirokaya A.V. , Pogorelov M.Y. , Melsitov A.V.
Published: June 2024

Purpose. To evaluate the eMectiveness of the technique of closing perforations of the nasal septum with a unilateral Nap of the nasal mucosa on the ethmoid arteries. Materials and methods. 56 patients with perforations of the nasal septum of various etiologies were operated on: postoperative — 24, traumatic — 6, idiopathic — 26. In the postoperative period, a cytological examination of smears from the surface of the nasal septum, a questionnaire with the NOSE questionnaire, and an assessment of mucociliary transport of the nasal mucosa were performed. The presence of recurrent perforation of the nasal septum was assessed within 1 year. Results. After surgery, pronounced leukocyte infiltration, bacterial contamination and low regenerative activity in the wound were revealed in the first 10 days. The indicators of mucociliary transport recovered by the 30th day (20.05±2.05 minutes), complete restoration of nasal breathing according to NOSE data by the 60th day (21.11 points). Uere were 12 relapses of perforations of the nasal septum: 4 cases — before 30 days, 5 cases — from 30 to 60 days, 3 cases — after 1 year, 7 of which were idiopathic, 4 were postoperative, and 1 relapse was in traumatic perforation of the nasal septum, in 75% relapses occurred in the early postoperative period. The effectiveness of the technique for closing the PPN with a Nap on the ethmoidal arteries was 78.5%. Conclusions. When forming a unilateral mucosal Nap for plastic surgery of perforation of the nasal septum, de-epithelialised areas heal by secondary tension through inflammation, which affects the final results of the operation and reduces the effectiveness of the technique.
SURGICAL TREATMENT OF TYMPANIC MEMBRANE RETRACTIONS WITH CARTILAGE GRAFTS
Authors: Gorbunova N.V. , Shirokaya A.V. , Morozov I.I.
Published: June 2024

Purpose. Based on LITERATURE review, to evaluate the effectiveness and outcomes of surgical treatment of tympanic membrane retraction pockets using tympanoplasty with a cartilage autograft. Materials and methods. The LITERATURE review included randomized and non-randomized controlled trials in which patients with retracted eardrum recesses underwent cartilaginous tympanoplasty. The criteria for excluding publications from the study were the presence of chronic purulent otitis media with cholestetoma, previous operations on the middle ear, the presence of concomitant pathology of the nasal cavity, and pharynx and paranasal sinuses, affecting the function of the auditory tube. Results. The studies included in this review showed wide heterogeneity regarding the type of study design, a number of treated cases, preoperative clinical examinations, management and methods of treatment monitoring, which makes it difficult to objectively interpret the results achieved. Conclusion. The use of an autocartilage graft was effective for the surgical treatment of retraction pockets of the tympanic membrane in 82-100% of the cases, and the recurrence rate was insignificant. Considering the variability of approaches to the management of patients with retraction pockets of the tympanic membrane, there is a need for a standardized diagnostic protocol and determination of indications for surgical treatment.
ORGANIZATIONAL AND LEGAL ASPECTS OF FIRST AID IN SPORTS MEDICINE
Authors: Rudyakov S. , Dezhurny L.I.
Published: June 2024

Organizational and legal aspects related to the first aid in sports medicine play a decisive role in ensuring high-quality and timely medical intervention in sports incidents. This article examines the issues of first aid in sports medicine from the point of view of national regulatory documents, presents basic definitions and concepts, studies the legal framework for providing first aid in sports medicine, and also the rights and responsibilities of medical staff when providing first aid.