bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating the Relationship Between Perceived Impact of Terrorist Attacks, Resilience, and Religious Beliefs on Death Anxiety in Students in Islamabad
Authors:   Department of Psychology, University of Wah, Rawalpindi, Pakistan., Khan Ayesha , Nasreen Rafig ,   Islamabad model college for girls, i-8/3, Islamabad, Pakistan.
Published: October 2023

Objectives The present research aims to explore the perceived impact of terrorist attacks on death anxiety in terms of dread, lack of control, and extent of exposure. In addition, this study is conducted to explore the moderating effect of resilience attributes and religious beliefs. Methods In this study, the samples include 359 students (directly perceived = 159, and indirectly perceived = 200). The students were in the age range of 15 to 22 years. The samples were collected from Islamabad City and Rawalpindi City, Pakistan. A total of 223 of the participants were male with a mean age of 18.97 years and a standard deviation of 2.48, and the remaining 136 participants were female with a mean age of 18.53 and a standard deviation of 2.68. The data were collected through the perceived impact of terrorist attack scale (Khan & Rafiq, 2016), the death anxiety scale (Templer, 1970), the resilience scale for adults (Friborg, 2003), and the religiosity questionnaire (Rafiq & Shehzadi, 2013). We used the quantitative research method in this study. After the data collection, they were analyzed using the SPSS software, version 23. Meanwhile, descriptive statistics, correlational analysis, and moderation was done. Results The results of the correlational analysis indicated that the perceived impact of terrorist attacks (dread, lack of control, and extent of exposure) was significantly and positively (P ≥ 0.001) associated with death anxiety among directly and indirectly perceived individuals; however, directly perceived individuals were less fearful about death when compared to indirectly perceived individuals. Religious beliefs and resilience attributes had moderating effects on the relationship between the perceived impact of terrorist attacks and death anxiety. Conclusion According to the findings, we can conclude that the belief about the hereafter, the presence of God, and coping may reduce death anxiety more in directly exposed individuals compared to indirectly exposed people.
Effect of Group Acceptance and Commitment Therapy on Body Image and Self-compassion of Women Undergoing Dialysis: A Randomized Clinical Trial
Authors:   Department of Educational Sciences, Faculty of Educational Sciences and Psychology, Mashhad Branch, Islamic Azad University, Mashhad, Iran., Pourfarahani Monireh , Shareh Hossein ,   Department of Educational Sciences, Faculty of Letters and Humanities, Hakim Sabzevari University, Sabzevar, Iran., Haji Arbabi Fatemeh ,   Department of Educational Sciences, Faculty of Educational Sciences and Psychology, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Published: October 2023

Objectives Dialysis for the treatment of chronic kidney failure has negative effects on the quality of life, daily activities, lifestyle, and physical, mental, and social health. The present study aims to assess the effect of group acceptance and commitment therapy (ACT) on the body image and self-compassion of women undergoing dialysis. Methods This is a quasi-experimental study (randomized clinical trial) with a pre-test/post-test/follow-up design. The study population consisted of all women receiving dialysis who were referred to the Dialysis Patients Support Association in Khorasan Razavi, Iran, in 2021-2022. Of these, 30 were selected by a convenience sampling method and were randomly assigned to two groups of intervention and control. The intervention group received group ACT at 10 sessions each for 120 minutes, while the control group received no intervention. Both groups completed the Body Image Concern Inventory and the Self-Compassion Scale in the pre-test, post-test, and two-month follow-up phases. The data were analyzed using the repeated measures analysis of variance in SPSS software, version 25. Results The intervention group showed a significant improvement in body image (F=39.271, P=0.001) and self-compassion (F=7.342, P=0.001) in the post-test phase compared to the control group, which remained stable in the two-month follow-up. Conclusion The group ACT can be a suitable method to increase body image satisfaction and self-compassion in women undergoing dialysis.
Launching A Specialized Clinic for Adults With Autism Spectrum Disorder in Roozbeh Hospital, Tehran, Iran
Authors:   Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran., Jamaloo Samira , Alaghband Rad Javad ,   Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran., Motamed Mahtab ,   Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Published: October 2023

This study aims to introduce a specialized clinic for adults with autism spectrum disorder (ASD) launched in Roozbeh Hospital, Tehran, Iran, in 2019. The target group is male and female adults (age>18) with ASD. The main goal of this clinic is the diagnosis, comprehensive evaluation, and evidence-based treatments, including medication therapy and psychotherapy. In addition, the academic department of this clinic pursues research and educational programs. Due to the prevalence of ASD in adults, we expected many clients to visit the clinic, but the number of cases recorded in this clinic so far has been much lower than expected. The reasons were discussed in this study. The launch of this clinic can be the starting point for creating a coherent ASD screening and diagnosis system and providing lifetime services to adults with ASD in Iran. We provide recommendations in this regard at the end of this paper.
Evaluating the Efficacy of School Mental Health Promotion Program in Iranian Schools: A Qualitative Study
Authors:   Department of Clinical Psychology, School of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran., Borji Mitra , Hajebi Amirali ,   Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran., Naserbakht Morteza ,   Mental Health Research Center, Health Research Institute, Iran University of Medical Sciences, Tehran, Iran., Ranjbar Helia ,   Department of administration, Faculty of Management, Tehran University, Tehran, Iran., Fazeli Asal ,   Department of psychology, Faculty of Psychology and Education, Allameh Tabataba'i University, Tehran, Iran., Khorrami Zahra ,   Department of clinical psychology, School of Behavioral Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran., Hajebi Ahmad ,   Research Center for Addiction & Risky Behaviors (ReCARB), Health research Institute, Iran Psychiatric Hospital, Iran University of Medical Sciences, Tehran, Iran.
Published: October 2023

Objectives Considering the importance of identifying the mental health problems among school students and their proper management by offering specialized services to them, the present study aims to evaluate the efficacy of school mental health (SMH) program in Iranian schools, identify its shortcomings and provide recommendations for it improvement. Methods This is a qualitative study using conventional content analysis method. A semi-structured in-depth interview was used to collect information from 35 participants who included teachers, principals, and developers of the SHM Program in Iran. Results Based on the results, four themes (strengths, weaknesses, barriers, and recommendations) and 14 subthemes were extracted. Overall, 50 codes were obtained. The results showed the effectiveness of the SMH program. Conclusion The SMH program is effective and has opened a new perspective to school-based interventions. However, expecting the full implementation and continuation of this program in the short term and with limited resources does not seem logical. Therefore, it is first recommended to improve the infrastructure for implementing this program, use trained personnel, upgrade the counseling departments of schools, and remove the time limit of teachers and legal limitations. Then, this project should be implemented at the national level for all schools in Iran.
Identification of Diagnostic Biomarkers by Bioinformatics Analysis in the Inflamed and Non-inflamed Intestinal Mucosa of Patients With Crohn’s Disease
Authors:   Department of Mesenchymal Stem Cells, the Academic Center for Education, Culture and Research, Qom, Iran, Sheykhhasan Mohsen , Fazaeli Hoda ,   Department of Mesenchymal Stem Cells, the Academic Center for Education, Culture and Research, Qom, Iran, Sheikholeslami Azar ,   Department of Mesenchymal Stem Cells, the Academic Center for Education, Culture and Research, Qom, Iran, Seyedebrahimi Seyed Abbas ,   Department of Mesenchymal Stem Cells, the Academic Center for Education, Culture and Research, Qom, Iran, Eshagh Hoseini Seyed Jalal ,   Department of Surgery, Qom University of Medical Science, Qom, Iran., Kalhor Naser ,   Department of Mesenchymal Stem Cells, the Academic Center for Education, Culture and Research, Qom, Iran
Published: October 2023

Background: Crohn’s Disease (CD) is a type of inflammatory bowel disease that, despite its unknown etiology, is generally associated with genetics, immune system, and environmental factors. In this study, we uncover transcriptional signatures in patients with CD and subsequently explain the putative molecular pathways in the inflamed and non-inflamed intestinal mucosa. Materials and Methods: We obtain GSE83448 gene expression profiles from the Omnibus gene expression database. Also, for the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of Differentially Expressed Gene (DEG) pathways, we used DAVID software. DEGs were detected in the inflamed and non-inflamed intestinal mucosa of CD patients compared to the control group using the GEO2R instrument. Significant modules and hub genes were identified after producing protein-protein interaction (PPIs) networks of DEGs using Cytoscape software. Results: The 10 specific hub genes of CD, including Matrix Metallopeptidase 2 (MMP2), Cadherin 1 (CDH1), Periostin (POSTN), Collagen type I alpha 2 chain (COL1A2), C-X-C motif chemokine ligand 8 (CXCL8), Collagen type III alpha 1 chain (COL3A1), JUN, Serine Protease Inhibitor clade E member 1 (SERPINE1), Integrin alpha M (ITGAM), and Connective Tissue Growth Factor (CTGF), were used as biomarkers to discriminate between inflamed and non-inflamed intestinal mucosa groups in patients. Conclusion: These findings could lead to new molecular targets and diagnostic biomarkers for both inflamed and non-inflamed intestinal mucosa in CD patients.
Decreased Gene Expression of Lipoxin A4 Receptor May Contribute to Nonallergic Rhinitis Pathogenesis
Authors:   Student Research Committee, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Jahangiri Samira , Lotfi Ramin ,   Lung Diseases and Allergy Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran, Mortazavi Seyed Hamidreza ,   Department of Pediatrics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Gorgin karaji Ali ,   Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Rezaiemanesh Alireza ,   Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Rashidpour Hatam ,   Department of Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran, Salari Farhad ,   Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Published: October 2023

Background: Rhinitis is a prevalent chronic inflammatory illness of the nasal mucosa. Arachidonic acid-derived lipoxin A4 (LXA4) has long been recognized to exert crucial antiinflammatory and pro-resolving effects on inflammatory responses through a specific receptor named LXA4 receptor/formyl peptide receptor-2 (ALX/FPR2). This study aimed to determine the serum level of LXA4 and the relative mRNA expression level of FPR2 in peripheral blood cells of patients with rhinitis (allergic and nonallergic) compared to healthy individuals. Materials And Methods: The study groups consisted of 37 patients with Allergic Rhinitis (AR), 16 patients with Nonallergic Rhinitis (NAR), and 20 sex- and age-matched healthy individuals. The measurement of LXA4 serum level was performed by the Enzyme-Linked Immunosorbent Assay (ELISA) technique, and the analysis of FPR2 mRNA expression level was performed by quantitative real-time PCR method. Results: The serum concentrations of LXA4 decreased in AR and NAR patients compared to healthy controls; however, this difference was not statistically significant (P>0.05). Besides, the mRNA expression level of FPR2 in peripheral blood cells of patients with nonallergic rhinitis was significantly lower than that in allergic rhinitis (P<0.05). Conclusion: Our results suggest that reduced gene expression of FPR2 may contribute to developing persistent and chronic nasal mucosa inflammation seen in NAR patients. Therefore, stable analogs of LXA4 and its receptor agonist may help develop new therapeutic approaches for rhinitis.
A Review on Suggested Mechanisms in Thrombocytopenia and Thrombosis Following ChAdOx1 nCoV-19 Vaccination
Authors:   Department of Pharmaceutics, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran, Mottaghi Dastgerdi Negar , Faghihi Homa ,   Department of Pharmacognosy and Pharmaceutical Biotechnology, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran
Published: October 2023

Background: ChAdOx1 nCov-19 vaccine is a viral vector-based vaccine with desirable protection (about 70.4%, two weeks after the second dose). Few reports were released on thrombocytopenia associated with thrombotic events shortly after the ChAdOx1 nCov-19 vaccination. However, the exact pathophysiologic mechanism of this vaccineinduced thrombotic complication has not yet been elucidated. Vaccine-induced thrombotic thrombocytopenia syndrome (VITTS) is associated with detecting anti-platelet factor 4 (PF4) antibodies that are not yet linked to previous exposure to heparin. Materials and Methods: In the current review, based on relevantly reported cases, possible mechanisms are suggested on the relationship between the anti-platelet factor 4 (anti-PF4) antibody assays, previous exposure to heparin, and the involved mechanisms of post-vaccination thrombocytopenia and thrombotic events, which might help the experts for selecting the appropriate therapeutic measures. Results: Possibly involved mechanisms in VITTS after ChAdOx1 nCoV-19 vaccination include binding of anti-PF4 antibodies to heparin/PF4 complex or receptor-binding domain (RBD) protein-PF4 complex. Another mechanism could be the binding of anti-RBD antibodies to the RBD protein-PF4 complex. Finally, anti-RBD or anti-PF4 antibodies may bind to the heparin-RBD protein-PF4 complex. The binding of either of the mentioned antibodies to these complexes via the Fc/angiotensin-converting enzyme 2 receptors can cause activation/removal of platelets leading to thrombocytopenia and thrombosis. Conclusion: The suggested mechanisms in this article provide a relationship between the results of anti-PF4 antibody assays, previous exposure to heparin, and the involved mechanisms of post-vaccination thrombocytopenia and thrombotic events, which might help the experts in selecting the therapeutic measures.
Evaluation of Dihydrofolate Reductase (Dhfr) Gene, Related to Plasmodium Falciparum Pyrimethamine Resistance in Imported Malaria Cases in Iran
Authors:   Student Research Committee, Mazandaran University of Medical Science, Sari, Iran, Shariatzadeh Seyyed Ali , Valadan Reza ,   Molecular and Cell Biology Research Center (MCBRC), Mazandaran University of Medical Sciences, Sari, Iran, Hosseini Seyed Abdollah ,   Department of Parasitology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran, Spotin Adel ,   Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, Shahbazi Abbas ,   Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran, Anvari Davood ,   School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran, Montazeri Fattaneh ,   Department of Parasitology, Faculty of Medical Sciences, Tarbiat Modarres University, Tehran, Iran, Javidnia Javad ,   Student Research Committee, Mazandaran University of Medical Science, Sari, Iran, Gholami Shirzad ,   Toxoplasmosis Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
Published: October 2023

Background: Antimalarial drug resistance is one of the important challenges for governments in the fight against malaria. Molecular surveillance of antimalarial drug resistance supports early detection of how the recommended treatments work. This allows immediate action to reduce any threat and prevent it from spreading. Therefore, the aim of this study was to evaluate the frequency of dihydrofolate reductase (dhfr) mutants in Plasmodium falciparum resistance to pyrimethamine in Iranian malaria patients. Materials and Methods: In 2020, 27 patients (21 males and 5 females) with imported P. falciparum cases were studied. The nested-PCR technique first confirmed the species in all samples and then amplification was done by the semi-nested-PCR method in order to detect single nucleotide polymorphisms (SNPs) in dhfr gene related to pyrimethamine resistance. Results: All samples in the 18S rRNA gene had species-specific bands for P. falciparum strains. In the sequence analysis of pfdhfr gene amplification after comparison with the standard strain (wild type), 21 patients had a double mutation (C59R+S108N) and six patients had a triple mutation (N51I+C59R+S108N) of pyrimethamine resistance. Conclusion: The results of this study showed that the susceptibility of P. falciparum to pyrimethamine in the treatment of malaria is significantly reducing. These findings can raise concerns about pyrimethamine resistance in P. falciparum. Due to the high emergence of double and triple mutants related to pyrimethamine resistance, the malaria surveillance and treatment systems in Iran, the use of pyrimethamine should be considered.
In Silico Design of a Multivalent Epitope Vaccine Against SARS-CoV-2 for Iranian Populations
Authors:   Department of Biology, Payame Noor University, Tehran, Iran., Soltanveis Faezeh , Nosrati Mokhtar ,   Zistfile Bioinformatics Center, Sanandaj, Kurdistan, Iran.
Published: October 2023

Background: Because of high genetic variation in human leukocyte antigen (HLA) alleles, epitope-based vaccines do not show equal efficacy in different human populations. Therefore, we proposed a multi-epitope vaccine against SARS-CoV-2 (severe acuterespiratory syndrome coronavirus 2) for Iranian populations. Materials and Methods: For this purpose, the proteins without allergenicity and high antigenicity, as well as conservancy levels from SARS-CoV-2, were chosen for computational epitope mapping. The T-cell epitope mapping process was performed based on the most frequent human leukocyte antigen (HLA) alleles in Iran. The B- and T-cell epitopes were determined based on their allergenicity, antigenicity, and hemolytic potential. Then, the epitopes with acceptable features were subjected to the final construct. The screened epitopes were structured in the final vaccine sequence. The secondary and tertiary structures of the proposed vaccine were predicted, and its affinity to HLA-I, HLA-II, toll-like receptor (TLR)-3, and TLR-4 were evaluated by the molecular docking method. Additionally, possible immune responses against the vaccine were predicted through immune simulation. Results: The final vaccine construct includes six linear B-cell epitopes, eight HLA-I restricted epitopes, and six HLA-II restricted epitopes. The evaluations confirmed that the proposed vaccine is a 60.3 kDa stable, water-soluble, and high antigenic protein with high affinity to the selected target molecules and could elicit both humoral and cellular responses. Conclusion: Altogether, the study results suggest that the planned vaccine can be an adequate anti-COVID-19 vaccine candidate for the Iranian population.
Antibiotic Resistance Profiles of Pseudomonas aeruginosa Isolates Containing Virulence Genes
Authors:   Department of Microbiology, University of Mohaghegh Ardabili, Ardabil, Iran., Ghazaei Ciamak
Published: October 2023

Background: A most common opportunistic pathogen, Pseudomonas aeruginosa is present in both humans and animals and responsible for various nosocomial infections and healthcare settings related infections. Different virulence genes like; oprL (membrane lipoprotein L) and toxA (exotoxin A i.e. ETA) in P. aeruginosa, assist in its pathogenicity, toxicity and contribute to high antibiotic resistance. So considering the risk of zoonotic transmission of P. aeruginosa through animal-related foods, this study aimed to monitor the prevalence of oprL and toxA virulence genes and antimicrobial resistance in P. aeruginosa isolates, obtained from animal (Cow’s milk) and human clinical samples. Material and methods: Of the total 120 collected samples for this study, every 60 samples were collected from animals and humans from respective laboratories. Total 76 isolates of P. aeruginosa were isolated and identified by morphological and biochemical tests. The presence of virulence factors like oprL and toxA were evaluated by PCR analysis and antimicrobial resistance was assessed by antibiotic susceptibility test (Kirby-Bauer method). Results: From the total 76, P. aeruginosa isolates obtained from both animal and human isolates, alone presence and coexistence of both toxA and oprL genes in P. aeruginosa isolates; were detected in PCR analysis. PCR analysis results showed in P. aeruginosa isolates, alone distribution of toxA and oprL genes is, 75% and 54.16% in animals, and 84.61% and 80.76% in humans, respectively. The coexistence of both genes was 37.50% and 40.32% in animals and human isolates, along with high antibiotic resistance in most P. aeruginosa isolates. Conclusion: Therefore, this study suggested PCR analysis can be used for fast and specific detection of oprL and toxA genes in P. aeruginosa. Monitoring of these genes can help to prevent the risk of transmission of multi-drug resistant P. aeruginosa, from animals to humans.
Relationship of Serotonin Transporter Gene Polymorphism With Temperament in Persian Medicine in Fars Province, Iran
Authors:   Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran, Aliabadi Shabnam , Zendehboodi Zahra ,   Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran
Published: October 2023

Background: Despite its effectiveness, there are still many concerns and questions about the principles and therapeutic methods of Traditional Medicine (TM). In other words, to accept TM as a reliable healthcare system, modern scientific research should approve the principles of this system. Temperament is one of the major determinants of Persian Medicine (PM), which is practically utilized to diagnose and cure diseases. Considering the association of depression with the coldness temperament and the serotonin-Tansporter-Linked Promoter Region (5-HTTLPR) polymorphism, we proposed that the serotonin transporter gene could be one of the candidate genes contributing to the specification of temperament. To test this hypothesis, we examined the association of 5-HTTLPR polymorphism with the hot/cold status of temperament in healthy individuals. Materials and Methods: The study included 351 healthy men (aged 20-40 years) referred to the organization of blood transfusion in Shiraz City, southern Iran. The participants’ temperament (warm, temperate, and cold) was determined using a standard self-reported scale. Then, we performed Polymerase Chain Reaction (PCR) to determine their 5-HTTLPR polymorphism genotype. Multinomial logistic regression was used to evaluate a 95% CI and odds ratios for the association of temperament with the 5-HTTLPR genotypes. Statistical analysis was performed using the SPSS at a significance level of less than 0.05. Results: Regarding the warm temperament, no association with the 5-HTTLPR genotypes was observed. However, regarding cold temperament, although our data showed no association with the SS, the LS genotype showed some association. With reference to LL, the LS genotype decreased the possibility of coldness rather than temperateness for the temperament (OR=0.471, P=0.040). Conclusion: Our data revealed the association of temperament with the 5-HTTLPR polymorphism, suggesting that the serotonergic system may influence temperament. Further studies are required to explore the relation of genetic factors with temperament.
IMPROVEMENT OF THE ORGANIZATIONAL AND ECONOMIC MECHANISM FOR DEVELOPING A REGIONAL DEVELOPMENT STRATEGY
Authors:   Sumy State Pedagogical University named after A.S. Makarenko, Kostyrko Diana
Published: October 2023

The development of a regional development strategy is a responsible task that determines the future level of economic, social, political and other aspects of life in the region. Therefore, the issues of choosing the conceptual framework for the development of a region, determining its strategic prospects, selecting tools and methodological support, and clarifying the organizational mechanism for strategy formation are relevant. The purpose of the article is to determine the directions for improving the organizational and economic mechanism for elaborating a regional development strategy. The object of research is the mechanism for developing a regional strategy. The subject of the study is the processes of regional strategy development. Research methods: logical analysis and generalization. The article proposes to expand the organizational and economic mechanism for developing a regional development strategy by supplementing it with an additional structural block "Communication Activity" in the motivational sub-mechanism. This provides an opportunity to stimulate change and intensify communications at the regional level in order to improve the interconnections between business, science and innovation systems (local, national and international levels), as well as to involve various target groups of stakeholders in strategizing. In general, such additions will contribute to the improvement of regional and national strategic development management systems. The results of this study can be implemented in the activities of regional authorities in order to increase the efficiency of strategic development management.
ASSESSMENT OF INNOVATIVE POTENTIAL IN THE REGIONAL DEVELOPMENT STRATEGY
Authors:   Cherkasy State Technological University, Mann Ruslan , Hladkii Dmytro ,   Cherkasy State Technological University
Published: October 2023

The paper is devoted to the analysis of the impact of innovation potential on the regional strategy and the development of an approach to its assessment in the system of strategic management of the region. The author of the paper assumes that sustainable regional development is possible if the innovative potential of the territory is activated. The paper solves the problem of comprehensive assessment of innovation potential from the standpoint of regional development strategy. In order to comprehensively evaluate the innovative potential in the concept of regional development, the author proposes to evaluate it according to four basic criteria: "innovative security", "innovative activity", "innovative security" and "innovative support". The last two criteria reflect the state's interest in supporting innovative activities and determine the vector of the region's development strategy. The author claims that the concept of strategic management of regional development should be based on the ideas of activating the innovative potential of territories, as this will contribute to the competitiveness of regions due to innovative solutions in all spheres of the economy. Effective use of the region's opportunities for innovative activity makes it possible to develop innovations, spread the principles of the knowledge economy, involve the business sector in high-tech developments, improve the quality of life of the population, and promote a positive image of the region. The assessment of innovation potential reveals the prospects for the further development of the region, the possibility of realizing regional and state national interests based on the knowledge economy. The peculiarity and advantage of the approach is a comprehensive assessment of the innovative potential and the opportunity to establish not only its state, but also the prospects for further activation. The results of the research can be useful for the system of state and regional management, as they substantiate the directions of formation of the regional development strategy. A promising direction of future research on this issue is modeling the influence of the innovative potential of territories on the system of regional interests.
DIGITALIZATION OF MIDDLE ENVIRONMENT AS A STRATEGIC ORIENTATION FOR THE DEVELOPMENT OF THE COUNTRY
Authors:   Cherkasy State Technological University, Mann Ruslan , Hladkii Dmytro ,   Cherkasy State Technological University
Published: October 2023

The article is devoted to the study of the process of digitalization of secondary education as a strategic reference point for the development of countries. The following key directions of the digital transformation of education are highlighted – the development of the digital infrastructure of education, the development of digital teaching and methodical materials, digital assessment and certification, the transition to a personalized organization of the educational process. The study analyzes the process of digitalization of secondary education in countries such as the Republic of Korea, Germany, the USA, and Ukraine. In the Republic of Korea, EDUNET can be mentioned among the information approaches, the application of which allowed to really improve the results of students. Also, the Republic of Korea pays special attention to the development and widespread distribution of digital textbooks, the use of which allows schoolchildren, using digital technologies, to learn the correctness of digital decision-making, independence. In Germany, the introduction of the «Digital School Pact» made it possible to promote the division of responsibilities between the federal government and the federal states and municipalities in the issue of the spread of information technologies in secondary education institutions. In the United States of America, digital library distribution strategies such as LearnSmart and Language Arts & Writing Redbird play an important role in making information more accessible to students and teachers. In Ukraine, the Plan for the Restoration of Education and Science plays an important role in the process of digitalization of secondary education. Among the strategic priorities of this plan: the introduction of electronic record-keeping in all educational institutions by the end of 2025, the formation of school reports automatically from the level of individual data and submission in electronic form by the beginning of 2026. Thus, it should be understood that global digitization forms a new digital culture of modern society, which requires a change in the education system in order to be ready to use the opportunities of all technological innovations.
УПРАВЛІННЯ ЛОГІСТИЧНИМИ ПРОЦЕСАМИ В УКРАЇНІ: ПРОБЛЕМИ ТА ШЛЯХИ РОЗВ’ЯЗАННЯ В УМОВАХ ВОЄННОГО СТАНУ
Authors: Кузяк Вікторія
Published: October 2023

В статті аналізуються та досліджуються проблеми, перспективи систем управління логістичними процесами в Україні в умовах воєнного стану. Проведено оцінювання стану вітчизняної логістичної системи напередодні воєнних дій та проблеми після повномасштабного вторгнення. Досліджено динаміку місць України в рейтингу Індексу ефективності логістики протягом 2007-2023 рр. та індексу ефективності логістики України та його складової (логістична компетенція) за аналогічний період. Визначено сутність поняття логістичного процесу, як об’єкту управління. Задля оптимізування логістичних процесів за умов війни запропоновано зосередитись на плануванні (прогнозуванні), коригуванні логістичних процесів, враховуючи безпекові питання, ризиковість, регулювати управління запасами, розглядати багатоваріантість постачання тощо. Запропоновано схему для оптимізування логістичних процесів в Україні за умов війни.
El apoyo social como parte de una intervención para prevenir la depresión en mujeres
Authors:   Instituto Nacional de Psiquiatría Ramón de la Fuente, Ansaldi Soledad , López Ingrid Berenice ,   Instituto Nacional de Psiquiatría Ramón de la Fuente, Lara Ma. Asunción ,   Instituto Nacional de Psiquiatría Ramón de la Fuente
Published: October 2023

Se pretende replicar la efectividad de una intervención psicoeducativa para prevenir la depresión (IPPD; Lara et al., 2003) al agregar un entrenamiento más específico que mejore las habilidades para obtener apoyo social. El diseño es aleatorio y comparativo entre dos condiciones, con evaluaciones pre, postratamiento y seguimiento. Se asignaron al azar 35 mujeres que solicitaron participar, de las cuales, 23 prosiguieron en el programa. Los MANOVA para síntomas de depresión (BDI-II; Beck, 1996), satisfacción y número de apoyos (Sarason et al., 1983) muestran diferencias significativas intra-grupos, pero no intergrupos y ningún cambio en el número de apoyos. Los resultados replican los del original en cuanto a efectividad, en reducir síntomas de depresión y aportan información respecto a su efecto en satisfacción con el apoyo social. Sin embargo, no se concluye que el entrenamiento en habilidades que fortalezcan dicho apoyo mejore la efectividad de la intervención en los aspectos evaluados.
Las instrucciones modulan el efecto del modo de respuesta en el aprendizaje causal
Authors:   Facultad de Estudios Superiores Iztacala. Universidad Nacional Autónoma de México, Alvarado García Angélica , Vila Javier ,   Facultad de Estudios Superiores Iztacala. Universidad Nacional Autónoma de México, López Romero Luis ,   Facultad de Estudios Superiores Iztacala. Universidad Nacional Autónoma de México
Published: October 2023

El objetivo del presente trabajo fue demostrar el efecto de las instrucciones posentrenamiento en los modos de respuesta ensayo-ensayo y global, en una tarea de interferencia en aprendizaje causal. En esta situación, los modelos asociativos predicen efecto de recencia, en el cual se responde acorde con los últimos ensayos del entrenamiento, mientras que los modelos estadísticos predicen un efecto de integración de fases, es decir, se responde conforme a todos los ensayos de la tarea. Se presentan dos experimentos en donde se manipularon los modos de respuesta cada 5 ensayos y global, así como las instrucciones posentrenamiento. Los resultados demostraron que al emplear el modo de respuesta ensayo-ensayo se observó un efecto de recencia, mientras que al usar el modo de respuesta global se evidenció un efecto de integración de fases. Asimismo, las instrucciones posentrenamiento permiten modular los efectos obtenidos por el modo de respuesta, de manera que se puede observar integración de fases en el modo ensayo-ensayo y recencia en el modo global. Así, las instrucciones posentrenamiento y el modo de respuesta pueden ser variables que permiten observar la flexibilidad del aprendizaje causal.
Caracterización de estudiantes de nuevo ingreso a la Universidad de Sonora: un estudio comparativo
Authors:   Universidad de Sonora, Irigoyen Juan José , Mares Cárdenas Guadalupe ,   Universidad Nacional Autónoma de México, Jiménez Miriam Yerith ,   Universidad de Sonora, Rivas Olga ,   Universidad Nacional Autónoma de México, Acuña Karla Fabiola ,   Universidad de Sonora, Rocha Héctor ,   Universidad Nacional Autónoma de México, Noriega José Gabriel ,   Universidad de Sonora, Rueda Elena ,   Universidad Nacional Autónoma de México
Published: October 2023

El presente estudio evaluó las condiciones económicas, sociales y académicas en una muestra de 176 estudiantes de nuevo ingreso (aproximadamente el 50% de la matrícula) a una institución de educación superior del Noroeste de México. Se aplicó un paquete de evaluación conformado por 7 secciones: 1) datos sociodemográficos, 2) trayectoria escolar, 3) nivel de conocimiento del ámbito disciplinario, 4) dominio de programas de cómputo, 5) cultura general, 6) aptitud para la ciencia y 7) comprensión de lectura en el idioma inglés. Se discuten los resultados comparándolos con una muestra equivalente de una institución de educación superior del centro de México, con un programa de estudios con orientación equivalente.
Análisis comparativo de la calidad de vida y la ansiedad en jóvenes estudiantes universitarios y adultos mayores
Authors:   Universidad Nacional Autónoma de México, González Celis Rangel Ana Luisa , Martínez Camarena Rebeca Laura ,   Universidad Nacional Autónoma de México
Published: October 2023

El propósito de la investigación fue describir la calidad de vida y ansiedad en 214 estudiantes universitarios y 176 adultos mayores. Se obtuvieron correlaciones moderadas, negativas y significativas entre calidad de vida y ansiedad en estudiantes y en ancianos. Se analizaron los problemas que más preocupaban a ambos grupos de estudio: problemas académicos (estudiantes) y problemas familiares (ancianos). Los ancianos percibieron mejor calidad de vida y menor ansiedad que los estudiantes. El ingreso económico afectó la calidad de vida de ambos grupos. Los ancianos que reportaron estar enfermos percibían un deterioro en su calidad de vida. Sólo entre mujeres se encontraron diferencias significativas en calidad de vida y en ansiedad entre muestras. Se concluye que la calidad de vida se afecta por la ansiedad en las muestras estudiadas. Palabras clave: calidad de vida, ansiedad, estudiantes universitarios, adultos mayores.
Asociación entre violencia y autoestima con respecto a las distintas etapas de vida en la mujer
Authors:   Instituto Nacional de Perinatología, Schnaas María de Lourdes , Ruiz González Celis Ana Paola ,   Universidad Anáhuac, Juárez Miranda Bertha Yvette ,   Universidad Anáhuac
Published: October 2023

El propósito de la investigación fue describir la calidad de vida y ansiedad en 214 estudiantes universitarios y 176 adultos mayores. Se obtuvieron correlaciones moderadas, negativas y significativas entre calidad de vida y ansiedad en estudiantes y en ancianos. Se analizaron los problemas que más preocupaban a ambos grupos de estudio: problemas académicos (estudiantes) y problemas familiares (ancianos). Los ancianos percibieron mejor calidad de vida y menor ansiedad que los estudiantes. El ingreso económico afectó la calidad de vida de ambos grupos. Los ancianos que reportaron estar enfermos percibían un deterioro en su calidad de vida. Sólo entre mujeres se encontraron diferencias significativas en calidad de vida y en ansiedad entre muestras. Se concluye que la calidad de vida se afecta por la ansiedad en las muestras estudiadas. Palabras clave: calidad de vida, ansiedad, estudiantes universitarios, adultos mayores.
La psicología como ciencia básica. ¿Cuál es su universo de investigación?
Authors:   Universidad de Guadalajara, Ribes Iñesta Emilio
Published: October 2023

Se examina la situación de la psicología como ciencia desde la perspectiva de su objeto y niveles de conocimiento. También se aborda la confusión existente en el empleo de diversos tipos de lenguaje, entre ellos, el lenguaje ordinario. Se propone un análisis del conocimiento científico en términos de cinco etapas de conocimiento, con lenguajes que cubren diferentes funciones lógicas.
La psicología como ciencia básica: entre la demolición y la purificación improbable
Authors:   Universidad de Barcelona, Gabucio Fernando
Published: October 2023

En este comentario se objeta la pretensión de una comparación demasiado directa de la cientificidad de disciplinas distintas, como la psicología por un lado y la química o la biol ogía por otro. No parece haber una teoría históricoepistemológica del desarrollo de las ciencias lo suficientemente articulada como para fundar tal comparación en criterios sólidos.
Demolición crítica de la torre de Babel de "la psicología"
Authors:   Universidad Nacional Autónoma de México, Hernández Pozo María del Rocío
Published: October 2023

Este ensayo revisa tres puntos centrales del artículo de Emilio Ribes titulado La psicología como ciencia básica, donde se cuestiona de manera crítica la existencia de una disciplina con un objetivo, metodología y aplicación identificable y propone un ejercicio colectivo consistente en el uso crítico del lenguaje y la evitación, a toda costa, de errores categoriales. A la luz de reflexiones y propuestas adicionales sobre el análisis de la conducta (Harzem, 2002, 2004, 2005; Mechner, 2008), se ofrece un ejemplo para la adopción de esa propuesta.
¿Qué hay de nuevo bajo el sol?
Authors:   Instituto de Investigaciones Médicas, Mustaca Alba E.
Published: October 2023

Mis comentarios apuntan a preguntas concretas sobre las propuestas que hace el autor acerca de las cinco estaciones en la investigación, la eliminación de conceptos ya conocidos y el abandono de la búsqueda de teorías y leyes de la naturaleza, sin especificar con qué se reemplazarían esos conceptos y qué se haría con lo ya conocido. En particular, no queda clara la metodología para el logro de las regularidades que se sugiere el autor con su propuesta. El aporte más importante es su énfasis en la solicitud de mejorar las ambigüedades del lenguaje en psicología para llegar a una mejor comprensión de los fenómenos por estudiar, aunque no elucida si el método es diferente de lo conocido en la ciencia en general.
Universo y lenguaje de la psicología
Authors:   Unidad Provincial de Sanidad de Barcelona, Pardos Peiro Antonio
Published: October 2023

Se analiza la crítica formulada por Ribes (2009) al universo actual de la psicología, fundamentalmente a la psicología mentalista, cuyas teorías descansarían en bases erróneas creadas a partir de las limitaciones inducidas por el lenguaje ordinario, enjuiciando el itinerario propuesto como solución para co rregir los diferentes equívocos categoriales introducidos por tal motivo en la psicología.
Analisis Harga Saham: Bukti Empiris pada Sub Sektor Kontruksi Bangunan di Bursa Efek Indonesia
Authors: Saifullah Muhammad Riza , Suwaidi Rahman Amrullah
Published: October 2023

The share price is the prevailing price on the stock exchange at a certain time. The findings from this study will help to ascertain whether Profitability, Liquidity, Solvency can contribute to the Stock Price of the Building Construction industry sub-sector on the Stock Exchange. There were 19 industries selected by applying purposive sampling technique. The findings of the study will be tested coming from secondary information, particularly the annual financial reports of the Indonesia Stock Exchange and panel information. Data analysis methods to validate hypothesis data include descriptive testing, classical assumption testing, and hypothesis testing using multiple linear regression analysis with the SPSS v25 program. The study findings prove (1) Profitability using a net profit margin proxy or net profit margin does not contribute to the building construction industry stock price on the Indonesia Stock Exchange; (2) Liquidity by proxy current ratio or current ratio cannot contribute to the building construction industry stock price on the Indonesia Stock Exchange; (3) Solvability by proxy debt to equity ratio or debt to equity ratio contributes to the share price of the building construction industry on the Indonesia Stock Exchange.
The Effect of Work-Life Balance and Workload on Job Satisfaction to Affect Nurse Performance
Authors: Permadi I Komang Oka , Diputra I Komang Suryadnya , Sanjiwani Putu Ari Pertiwi
Published: October 2023

In the process of providing service, nurses are the most interactive healthcare personnel with patients. Nurses in public hospitals have a huge responsibility for providing quality health care. The study aims to confirm and re-test the impact of work-life balance and workload on job satisfaction and the performance of nurses. The sample determination uses the nonprobability sampling method with the technique of taking saturated samples (sensus), so that the entire population of 32 people is the sample. Path analysis is used to test hypotheses in research using SmartPLS version 3.2.9. The study revealed that work-life balance showed a significant positive impact on job satisfaction but no significant impact on nurses’ performance; the workload on an informed nurse’s job satisfaction can have an equally significant positive effect on the performance of the nurse; the satisfaction of the real job does not have a significant effect on the nurse's performance; and job satisfaction cannot affect the impact of work-life balances and workloads on the nurse's performance.
Pengaruh Penghasilan Rendah, Inflasi dan Total Penduduk pada Produk Domestik Bruto Regional Indonesia
Authors: Rahmi Fadhillah , Fitrawaty Fitrawaty , Rahmadana Muhammad Fitri
Published: October 2023

Regional gross domestic product is the value of goods and services produced in that country in a given period. This study aimed to find out how low income, inflation and total population affect the regional gross domestic product. The research was conducted using a quantitative descriptive method. This study was conducted in 34 provinces in Indonesia between 2010 and 2020. The research sample was 34 provinces with an 11-year research period, so the results of observations in the study were 369 data. The data analysis used in this study was Panel Data Regression Analysis using Eveiws 9 software. The coefficient of determination test yielded a value of 0.866983 or 86.6983%, which means that the independent variables, namely low income, inflation and total population, can explain regional gross domestic product results. The results of the F test show that low income, inflation and total population significantly affect regional gross domestic product results. The t-test shows that low income positively and significantly affects the regional gross domestic product. In contrast, the inflation and total population variables have no effect on Indonesia's regional gross domestic product for the 2010-2020 period.
Analisis Variabel-variabel Penguat Kewirausahaan Sosial untuk Pengentasan Kemiskinan Keluarga
Authors: Yuafi Hamdan , Nabhan Faqih
Published: October 2023

This research was conducted based on a big question of what kind of social entrepreneurship could increase the condition of familiy to alleviate poverty. In this study, we take four variables that can improve the relationship of social entrepreneurship and family poverty alleviation, these are Zakat Infaq Shodaqoh (ZIS) for business purposes, financial literacy, social facilitation and frugal social innovation. The last variable is a new variable that has never existed before. Researchers synthesized these variables from two different variables, namely Social Innovation and Frugal Innovation.The method used in this study is Mixed Research with an Explanatory Sequential Design approach, which combines quantitative data analysis and then confirmed the results through in-depth interviews. This study took a sample of 195 Beneficiary Families (KPM) of the Program Keluarga Harapan (PKH) in Semarang Regency. One of the results taken into account in this study is that social entrepreneurship coupled with good financial knowledge can increase the condition of familiy to alleviate poverty optimally or significantly. Meanwhile, from the partial analysis, it is shown that the variables of social entrepreneurship, financial literacy and frugal social innovation and social assistanceship have a positive and significant effect on poverty alleviation.