bluuebunny/crossref_metadata_2025 huggingface dataset:
ANÁLISE DAS MANIFESTAÇÕES PATOLÓGICAS EM UMA ESTRUTURA DE CONTENÇÃO NO BAIRRO DE LINHA DO TIRO - RECIFE/PE
Authors: Brito Kleiton de Albuquerque , Bezerra Jonas da Silva , Costa Lorena Vila Bela , Lafayette Kalinny Patrícia Vaz , Dias Andréa Batista de Farias
Published: November 2024

As estruturas de contenção de morros e encostas são comuns no cenário urbano de Recife, especialmente em áreas ocupadas por populações de baixa renda, que enfrentam o temor dos impactos causados por fatores climáticos adversos. Este estudo tem como objetivo identificar e analisar as manifestações patológicas presentes em uma estrutura de contenção localizada no bairro Linha do Tiro, na cidade de Recife-PE, e elaborar um mapa de danos dessa estrutura. A pesquisa incluiu levantamento bibliográfico sobre o tema, visita técnica à região, e registro fotográfico com georreferenciamento. Com as informações coletadas, foram destacadas as patologias observadas, e, com base nesses dados, foi gerado um mapa de danos, que permite uma visualização clara e intuitiva das condições da edificação. As patologias encontradas podem ter diversas origens, como execução inadequada, uso incorreto de materiais, ações antrópicas desordenadas, falta de manutenção preventiva e fenômenos climáticos imprevisíveis. Ao final, espera-se que o mapa de danos gerado auxilie na implementação de medidas corretivas mais eficazes, contribuindo para a melhoria das condições dessas estruturas de contenção.
DIFICULDADES NO ENSINO DE GEOCIÊNCIAS E A MULTIPLICIDADE DE FATORES: ANÁLISE CONCISA E LEVANTAMENTO CRÍTICO DE UM CURSO DE ENGENHARIA DE PETRÓLEO
Authors: Marques Suelen Nonata de Souza , Campos Alfredo Borges de
Published: November 2024

Este artigo analisa de modo conciso as experiências da prática docente no ensino de geociências em um curso de engenharia de petróleo, objetivando-se o apontamento das condições de oferta e a identificação dos problemas educacionais, para fins de planejamento pedagógico eficaz na difusão da geologia em cursos afins. Os diferentes currículos da geologia tornam-a uma ciência especialmente compensatória na interdisciplinaridade durante a aprendizagem, contudo o interesse por temas de geociências em cursos de engenharias vem confirmando índices regressivos nas competências de aprendizagem, visto que as atividades letivas compreendem caráter essencialmente matemático. A metodologia utilizada foi baseada na análise de currículo do curso, nas práticas pedagógicas e metodologias de ensino aplicadas e nas condições estruturais ofertadas. Os resultados mostram que há a necessidade de revisão das metodologias empregadas, bem como nos temas abordados em disciplinas quem empregam as geociências, além da latente necessidade de reestruturação física do espaço institucional, o que repercute em índices progressivos de reprovação, baixo interesse pela pesquisa e aumento considerável de evasão escolar por parte do corpo discente, cujo curso é regido por questões administrativas delicadas que influenciam sobremaneira o ensino de geologia.
A ATENÇÃO PRIMÁRIA À SAÚDE E A ATUAÇÃO DO CIRURGIÃO DENTISTA SOB AS PERSPECTIVAS DA BIOÉTICA
Authors: Netto Moysés Francisco Vieira , Schneider Danielle Karla Garioli Santos , Alves Rubia Caus Pereira
Published: November 2024

A Atenção Primária à Saúde (APS) é o primeiro ponto de contato do cidadão com o Sistema Único de Saúde (SUS), integrando uma rede hierarquizada que facilita o acesso a serviços de saúde e promove cuidados abrangentes. A Odontologia, inserida nesse contexto, desempenha um papel essencial, não apenas no tratamento, mas também na prevenção de doenças, contribuindo para uma melhor qualidade de vida. Este estudo examina a inter-relação entre bioética e expansão dos cuidados na APS, destacando a importância de fortalecer vínculos e humanizar o atendimento. A pesquisa adota uma abordagem descritiva e se apoia em revisão bibliográfica, utilizando referenciais que sustentam o Código de Ética do Conselho Federal de Odontologia e a Política Nacional de APS. A conclusão enfatiza que uma compreensão mais ampla da bioética é crucial na prática odontológica, pois fortalece e consolida a APS, promovendo um cuidado mais completo e ético para os indivíduos e comunidades que dela dependem.
El rock alternativo como vínculo de tradición e identidad nacional en la generación Z
Authors: Antón Chávez Alina del Pilar
Published: November 2024

Marcado por su constante adaptación, el rock ha acompañado a los jóvenes de todas las generaciones, contribuyendo al vínculo entre tradición e identidad nacional. El estudio se propuso demostrar esta relación en una encuesta aplicada a 410 estudiantes de entre 17 y 24 años (generación Z o centennial) de la Universidad Nacional de Piura, tomando como referencia “Triciclo Perú”, una canción de rock alternativo de los años noventa.  Los resultados muestran que los jóvenes consideran que la canción “Triciclo Perú” permite evidenciar esta articulación (63,7%) en los elementos de música criolla que contiene, mostrando la esencia del Perú (96,6%) determinada por sus raíces ancestrales (40,7%). Se concluye que independientemente de las características de cada generación, existen factores como la música que facilitan esta relación y, por tanto, fortalecen la identidad nacional.
Digital Transformation and Enterprise Financialization: The Role of Operating Capacity
Authors: Wen Meini
Published: November 2024

Digital Transformation (DT) is a new business model developed by adopting digital technologies. DT creates opportunities for enterprises to gain and collect information on operations for visible analysis. Due to the benefits of DT as well as the harms of Enterprise Financialization (EF), the impact of DT on EF and its mechanism are worthy of further investigation. In this paper, Chinese public enterprise observations of the panel data from 2011 to 2020 are adopted to investigate the impact and the mechanism of DT on EF. The results show that DT can restrain EF through enhancing Operating Capacity (OC). More specifically, this effect is much more pronounced in state-owned enterprises (SOEs), start-up enterprises, and board minor-size enterprises. The findings provide contributions for digital transformation policy enactment as well as suggestions for enterprises to improve OC and reduce EF tendencies.
THE INFLUENCE OF PRODUCT INNOVATION, CUSTOMER EXPERIENCE, BRAND TRUST AND CUSTOMER LOYALTY ON COMPANY PROFITABILITY AT PT. RAHIM MAJU JAYA BATAM
Authors: Sembiring Diamon , Putra Arif Eka , Yona Mira
Published: November 2024

This study aims to determine the influence of product innovation, customer experience, brand trust and customer loyalty on company profitability. The population in this study were customers of PT. Rahim Maju Jaya Batam as many as 50 people. The sample in this study amounted to 50 people taken using a saturated sampling technique involving all populations as research samples. This type of research is a quantitative type using primary data collected using a questionnaire technique. The analysis method used is multiple linear regression processed using the SPSS 25 application The results of the study stated that product innovation and brand trust did not have a significant effect on company profitability, but customer experience and customer loyalty had a significant effect on company profitability. Product innovation, customer experience, brand trust and customer loyalty partially and simultaneously have a positive and significant effect on company profitability at PT. Rahim Maju Jaya Batam.
JUNIOR HIGH SCHOOL STUDENTS' PERCEPTIONS OF PROBLEM BASED LEARNING MODEL IN SCIENCE LEARNING
Authors: Febriani Febby , Azki Muhammad , Oktavia Rani
Published: November 2024

Problem Based Learning (PBL) is a learning approach that is often used in education in recent years. The purpose of this article is to find out how junior high school students perceive PBL model in science class and the benefits of PBL model in science learning. To find data related to junior high school students' perceptions of problem-based learning models in science classes, the researcher conducted a systematic review of several relevant sources with a period from 2014 to 2023, following the principles of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Based on the research results, it is known that the problem solving ability of students who learn using the PBL model is better than students who learn with conventional models. The results of this study prove PBL as an effective learning method for science compared to conventional teaching methods. PBL method is perceived to improve students' knowledge and communication skills. Based on several research results that have been conducted, it can be concluded that the PBL model has a positive impact on learning.
THE DEVELOPMENT OF PROJECT BASED LEARNING E-MODULE ABOUT STRUCTURE AND FUNCTION OF LIVING CREATURES TOPIC
Authors: Monica Friscilia , Putri Rahmah Evita , Putri Azza Nuzullah , Arif Khairil
Published: November 2024

The general background of this research is the limited teaching materials equipped with project-based learning assessment instruments as recommended in Kurikulum Merdeka. The purpose of this research is to produce a Project Based Learning (PjBL) based e-module on the structure and function of living creatures topic that is valid, practical and effective.The type of research used is Research and Development (R&D) with 4-D model’s consisting of the stages of defining, designing, developing and disseminating. However, this research was only untill the development stage due to time constraints. The research instruments consist of teacher questionnaires, student questionnaires, validity test questionnaires, practicality test questionnaires, and effectiveness test questionnaires. The data obtained was analyzed using a formula to analyze the results of validity, practicality and effectiveness tests. The research results show that the PjBL-based e-module developed is valid with an average 88%. The level of practicality is practical with an average 88%. The level of effectiveness is effective which is 84% ​​on average. Based on the research results, it can be concluded that the PjBL-based science learning e-module on the material Structure and Function of the Body of Living Creatures meets the valid, practical and effective categories.
THE INFLUENCE OF DIGITAL COMICS ON STUDENTS’ LEARNING OUTCOMES
Authors: Aprianti Reka aprianti , Akhbar M Taheri , Selegi Susanti Faipri
Published: November 2024

This study aims to determine whether or not there is an influence of digital comics on the science learning outcomes of fifth grade elementary school students on single substance and mixed substance material. The research method used was quantitative with true experimental and was designed using a Pretest-Posttest Control Group Design research design. The sample size for the research was 58 students who were divided into 2 groups, namely class V.A, which had 29 students as the experimental class and class V.B, which had 29 students as the control class. levence statistics, hypothesis testing using the t-test stated that both classes showed an rcount7.588 >ttable 1.672and the sig (2-tailed) value shows 0.000 < 0,05of  So it can be concluded that Ha is accepted. Based on this research data, it can be proven that there is an influence of digital comics on the science learning outcomes of fifth grade elementary school students in single substance and mixed substance materials.
Chorologické doplnky k cievnatým rastlinám Národného Parku Nízke Tatry
Authors: Turis Peter
Published: November 2024

Floristický výskum oblasti zahŕňajúcej Národný park Nízke Tatry aj s ochranným pásmom má dlhodobú históriu a jeho výsledky boli uverejnené v mnohých prácach (cf. Turis 2004). Prehľad taxónov celého územia však doposiaľ nie je vypracovaný a tento zoznam sa neustále rozširuje nielen v dôsledku detailnejšieho prieskumu regiónu, ale aj vďaka taxonomickému bádaniu botanikov, zavliekaniu nových druhov, alebo migrácii rastlinstva. Početné publikácie sú venované aj upresňovaniu rozšírenia jednotlivých taxónov v území. Rovnako aj predložená práca je zameraná na doplnenie chorologických údajov z uvedenej oblasti. Jej ďalším cieľom je na základe aktuálne zistenej distribúcie rastlín identifikovať floristicky najcennejšie časti sledovaného územia a vytvoriť prehľad najvýznamnejších rastlinných druhov.
Speech communication in modern Russia: Chronicle of the 6th International Scientific Conference
Authors: Terskikh M.V.
Published: November 2024

The article provides an overview of the traditional International Scientific Conference “Speech Communication in Modern Russia” and the 5th International Scientific School “Communicative Linguistics”, held on the basis of the Faculty of Philology and Media Communications of Dostoevsky Omsk State University (September 27 - October 1, 2021).
The Rise of AI Pricing: Trends, Driving Forces, and Implications for Firm Performance
Authors:   University of Florida, Adams Jonathan , Fang Min ,   University of Florida, Liu Zheng ,   Federal Reserve Bank of San Francisco, Wang Yajie ,   University of Missouri
Published: November 2024

We document key stylized facts about the time-series trends and cross-sectional distributions of AI pricing and study its implications for firm performance, both on average and conditional on monetary policy shocks. We use the universe of online job posting data from Lightcast to measure the adoption of AI pricing. We infer that a firm is adopting AI pricing if it posts a job opening that requires AI-related skills and contains the keyword “pricing.” At the aggregate level, the share of AI-pricing jobs in all pricing jobs has increased by more than tenfold since 2010. The increase in AI-pricing jobs has been broad-based, spreading to more industries than other types of AI jobs. At the firm level, larger and more productive firms are more likely to adopt AI pricing. Moreover, firms that adopted AI pricing experienced faster growth in sales, employment, assets, and markups, and their stock returns are also more sensitive to high-frequency monetary policy surprises than non-adopters. We show that these empirical observations can be rationalized by a simple model where a monopolist firm with incomplete information about the demand function invests in AI pricing to acquire information.
Study on Single and Combination of Galangal, Turmeric, and Ginger Ethanol Extracts as Anthelmintic
Authors: Azhari Muhammad , Sengaji Riki Febriansyah , Hadisoebroto Ginayanti , Al-Badri Faiq Muhamad Fathan
Published: November 2024

Soil-Transmitted Helminth infection (STH) such as ascariasis, has become one of the most persistent parasitic diseases in most developing countries, including Indonesia. Galangal, turmeric, and ginger plants are known to provide various of pharmacologically active substances which commonly used as antibacterial, aphrodisiac, and antiparasitic. This research was aimed to study the anthelmintic activity of ethanol extract of ginger, turmeric, galangal in single extract as well as their combination against Ascaris suum Goeze as a model. The anthelmintic activity was analyzed by determining the profile of time of paralysis (TOP), time of death (TOD), and the IC50­ of the inhibition activity from single extracts and extract combinations as well as the combination index (CI). The results showed that galangal, turmeric, and ginger ethanol extract have anthelmintic activity with IC50 7.66, 22, and 13,14 mg/mL, respectively. Meanwhile, the IC50 values for the extract combination of galangal with turmeric (KL), galangal with ginger (JL), and turmeric with ginger (JK) were 10.22; 3.92; and 34.93 mg/mL, respectively. The synergistic combination properties were shown by combination of galangal with turmeric extracts and galangal with ginger extracts with the combination index (CI) 0,67 and 0,38, respectively.
Antioxidant Activity and Total Carotenoids Level of Litopenaeus vannamei
Authors: Fawwaz Muammar , Baits Muzakkir , Pratama Mamat , Abidin Zainal
Published: November 2024

Udang putih (Litopenaeus vannamei) merupakan salah satu spesies Crustacea yang cangkangnya mengandung senyawa karotenoid. Senyawa ini merupakan antioksidan alami yang berpotensi tinggi. Penelitian ini bertujuan untuk mengetahui karotenoid total pada ekstrak cangkang L. vannamei dan mengevaluasi aktivitas antioksidannya secara in vitro. Ekstrak diperoleh dengan cara maserasi menggunakan n-heksan. Tingkat total karotenoid dalam ekstrak ditentukan setara dengan β-karoten. Spektrofotometer UV-Visible mengukur ekstrak dan larutan standar referensi pada panjang gelombang maksimum β-karoten (462 nm). Dua metode berbeda digunakan dalam menentukan aktivitas antioksidan ekstrak; metode peredaman radikal 1,1-diphenyl-2-picryl-hydrazyl (DPPH) dan metode ferric reducing antioxidant power (FRAP). Hasil penelitian menunjukkan bahwa karotenoid total dalam ekstrak cangkang L. vannamei adalah 5,87 mg/g, setara dengan β-karoten. Konsentrasi hambat setengah (IC50) ekstrak dengan metode DPPH adalah 27,59 µg/mL menunjukkan potensi sedang sebagai antioksidan dibandingkan dengan kuersetin standar sebesar 1,28 µg/mL. Kapasitas antioksidan ekstrak dengan metode FRAP dinyatakan dalam mg setara kuersetin (QE) per g ekstrak (mgQE/g), dan hasilnya menunjukkan potensi penghambatan sebesar 1,65 mgQE/g ekstrak. Dengan demikian, dapat disimpulkan bahwa ekstrak cangkang udang vannamei sangat potensial sebagai sumber karotenoid alami dengan efek antioksidan yang memadai.
Cytotoxic Effects of Hibiscus surattensis L. Leaves Extracts on BSLT, MCF-7 and Hela Cells
Authors: Susanto Yuliet -
Published: November 2024

Hibiscus surattensis L. leaves have been known as a folk medicine. Several previous reports have shown several potential therapeutic effects, including antidiabetic, antibacterial, anti-diarrheal, analgesic, hepatoprotective, and antioxidant, but no toxicity study is similar to the current one. Therefore, it is necessary to investigate the cytotoxic effect of these commonly consumed medicinal leaves. This study aimed to investigate the cytotoxicity of Hibiscus surattensis L. leaves extract (HSL). The cytotoxic effect was determined through brine shrimp lethality bioassay (BSLT) and in vitro Presto Blue assay of MCF-7 and Hela cell.  HSL extract was obtained by maceration using 96% ethanol. The BSLT results showed that the HSL has LC50 value of 224.814 μg/mL. MTT assay results showed the IC50 value of the HSL extract on MCF-7 cells was 1419.83 μg/mL, and Hela cells were 2050.50 μg/mL. Based on the LC50 value that has been analyzed against HSL extract shows an LC50 value of less than 1000 μg/mL which can be concluded while having potential cytotoxic activity against experimental animal larvae of A. salina Leach. The results of the cytotoxic test with Presto Blue assay on two cancer cells used showed that the HSL extract was not toxic.
Efektifitas Asap Cair Kayu Sengon (Falcataria moluccana) Sebagai Antiseptik Secara In Vivo dan In Vitro
Authors: Zaenudin Arif Jihan Ahmad
Published: November 2024

Bakteri dan jamur merupakan penyebab utama penyakit infeksi, pencegahan dapat diatasi dengan penggunaan hand sanitizer, tetapi dapat menimbulkan efek samping iritasi, maka diperlukan bahan alternatif alam. Asap cair kayu sengon memiliki kemampuan sebagai antiseptik. Penelitian ini bertujuan untuk mengetahui efektivitas asap cair kayu sengon sebagai antiseptik terhadap pertumbuhan mikroba secara in vitro dan in vivo. Hasil uji in vitro didapatkan zona hambat tertinggi pada asap cair kayu sengon grade 1 terhadap E. coli ATCC 25922 konsentrasi 75% 5,8 mm.  S. aureus ATCC 25923 konsentrasi 75% 10 mm. A. flavus ATCC 9643 konsentrasi 75% 22,8 mm. C. albicans ATCC 10231 konsentrasi 75% 3,6 mm. Grade 2 terhadap E. coli ATCC 25922 konsentrasi 75% 7,5 mm. S. aureus ATCC 25923 konsentrasi 75% 12 mm. A. flavus ATCC 9643 konsentrasi 75% 27,8 mm. C. albicans ATCC 10231 konsentrasi 75% 5,1 mm. Hasil uji in vivo menunjukan efektivitas asap cair kayu sengon grade 2 pada bakteri sebesar 54,51%, jamur sebesar 84,37%. Dari data kuesioner responden diperoleh 75% menyukai warna, 41% menyukai aroma, 75% tidak menimbulkan efek kekeringan, 92% tidak mendapatkan efek samping. Dapat disimpulkan asap cair kayu grade 2 konsentrasi 75% memiliki kemampuan dalam menghambat pertumbuhan mikroba.
PERANCANGAN HEWAN MODEL MALNUTRISI ENERGI PROTEIN UNTUK PENGUJIAN PRODUK ANTISTUNTING
Authors: IH Hariyanto , Fajriati Inarah , Nugraha Fajar , Hadi Kurniawan , Nurbaeti Siti Nani , Ardianto Verdi
Published: November 2024

Produk antistunting menjadi inovasi dalam mengatasi permasalahan malnutrisi, namun keterbatasan pemodelan hewan uji menjadi salah satu hambatan dalam pengembangan produk tersebut. Penelitian ini bertujuan menciptakan hewan model malnutrisi melalui formulasi pakan rendah protein. Formulasi pakan rendah protein dari tepung maizena dan tapioka diberikan kepada hewan uji yang dibagi ke dalam 3 kelompok, yaitu kelompok normal, kelompok maizena dan kelompok tapioka. Induksi pakan dilakukan 15 hari dimana kelompok normal diberikan pakan CP551, sedangkan dua kelompok uji masing-masing diberikan pakan formulasi. Perubahan bobot badan tikus dianalisis selama 15 hari perlakuan. Parameter malnutrisi, yaitu kadar hemoglobin, albumin dan protein total pada darah hari ke-0 (sebelum perlakuan) dan hari ke-15 (setelah perlakuan) diukur dan dibandingkan. Hasil pengamatan bobot badan menunjukkan kedua pakan formulasi rendah protein dapat menciptakan kondisi malnutrisi setelah dibandingkan terhadap kelompok normal (p<0,05). Persentase penurunan kadar hemoglobin, albumin dan protein total terbesar ditunjukkan oleh kelompok maizena dengan nilai penurunan masing-masing sebesar 5,68%; 12,70% dan 7,64% dibandingkan kelompok tapioka dengan penurunan masing-masing sebesar 0,53%; 2,30% dan 4,74%. Namun, tidak terdapat perbedaan signifikan perubahan bobot badan antara dua kelompok uji (p>0,05). Formulasi pakan rendah protein dari tepung maizena dan tapioka dapat menciptakan kondisi malnutrisi pada hewan uji dengan formulasi terbaik diberikan oleh pakan maizena.
Aportes de la teoría política al análisis político en procesos de intervención social
Authors: Escudero Carolina , Sarmiento Julio , Payo Mariel
Published: November 2024

El trabajo aquí presentado se centra fundamentalmente en nuestra experiencia como docentes de la Especialización en intervención social con niñas, niños, adolescentes y jóvenes. Así, las reflexiones que compartimos están doblemente determinadas, por un lado, porque es una reflexión situada derivada de un ejercicio de enseñanza teórica y, por otro lado, porque las herramientas de análisis que proponemos están determinadas por la consideración de les destinataries de aquella experiencia, agentes de intervención estatal con un perfil profesional muy marcado. Sabemos que una cuestión que atraviesa los escenarios de la intervención social es la expresión de “lo político” o cómo lo político se convierte en una de sus determinaciones más significativas. A su vez, la propia intervención profesional se ve permanentemente interpelada por lo político: las relaciones de poder y dominación -inherentes a los problemas que la movilizan- tensan la propia práctica profesional. En ese sentido, un desafío importante de los procesos de intervención es el análisis de lo político, por esto es que nos proponemos revisar algunos aportes teóricos que permiten: caracterizar lo político delimitándolo de otras actividades o prácticas sociales; distinguir los hechos políticamente relevantes; y analizar las relaciones de poder y dominación que estructuran lo político. Creemos que esos aportes, tomados en su conjunto y de manera sistemática, constituyen una posible matriz inicial y básica para el análisis político situado o el análisis político en los escenarios de intervención.
Humanistic approach in protecting victims of human trafficking crimes
Authors: Siswanto Heni , Fathonah Rini , Anam Haidir , Gunawan Andre , Gustiara Nisa
Published: November 2024

Cases of human trafficking are becoming more prevalent and represent grave abuses of human rights. Both locally and internationally, victims of human trafficking run the danger of being exploited, violent, or infected with contagious illnesses. The Indonesian government has not fully complied with the minimal criteria for safeguarding victims of human trafficking, notwithstanding Law Number 21 of 2007 for the Eradication of the Crime of Human Trafficking. Human rights restoration and respect for victims of human trafficking must be given priority in the implementation of legal protection for these individuals. To strengthen and increase the security of victims’ rights in the future, this study intends to conduct a thorough analysis of the humanism approach model and policies for safeguarding victims of human trafficking. This research uses an empirical technique to support its normative legal analysis. Primary and secondary legal sources are used in this research. The study’s findings show that the protection provided by humanist criminal law for victims of human trafficking is founded on humanitarian principles that derive from the divine principles found in the Pancasila ideology. There are additional requirements for punishment, such as its purpose, its ability to serve as therapy, and its determination to reflect the victim’s and society’s sense of justice. This criminal law is founded on the principles of legality and balance.
Evaluating the mixed convection flow of Casson fluid from the semi-infinite vertical plate with radiation absorption effect
Authors: Sonam  , Yadav Rajendra Singh
Published: November 2024

This study examines a steady laminar Casson fluid flow induced by a semi-infinite vertical plate under the impact of the Darcy-Forchheimer relation and thermal radiation. The features of mixed convection, cross-diffusion, radiation absorption, heat generation, chemical reactions and viscous dissipation are also considered to explain the transport phenomenon. The resultant system of equations, concerned with the problem under consideration, is transformed into a group of non-linear ordinary differential equations (ODEs) by means of similarity variables. The bvp4c method, an instrument popular for its numerical accomplishments, is utilized to solve this problem. The effect of flow parameters on heat transfer, concentration and velocity is evaluated via diagrams. To validate our code, we have compared the present outcomes to the prevenient literature, and stable consent has been detected. Moreover, the friction coefficient Cfx, Nusselt number Nux, and Sherwood number Shx are also computed to assess velocity gradient, efficiency of heat transfer and mass transfer process, respec-tively.
Perubahan Preferensi Menonton Film pada Era Media Sosial: Dampak Short Video dan Implikasinya pada Perilaku Menonton Film
Authors: Verakandhi Diyah
Published: November 2024

This research investigates changes in film viewing preferences in the context of the social media era. The main focus of the research is the impact of short videos reviewing films and their implications for film watching behavior. In the face of dramatic changes in film accessibility and the influence of social media, this research seeks to understand how short videos, especially those containing spoilers, influence the way viewers enjoy and appreciate films. The research method used is a mixed method, namely qualitative and quantitative involving surveys, short video content analysis, and interviews with film producers and directors. The findings of this research illustrate significant changes in film viewing preferences and their implications for the way audiences explore and enjoy film works. This research provides in-depth insights into the transformation of film viewing behavior in the dynamic social media era and proposes recommendations that can be useful for the film industry and social media content creators.
PRODUÇÃO DE PROTEASES E CELULASES FÚNGICAS A PARTIR Aspergillus sp NA01 e Paecilomyces sp.TP08 UTILIZANDO ENGAÇO DE UVA COMO SUBSTRATO
Authors: Andrade Eline de Souza Pontes , Grisi Cristiani Viegas Brandão , Cabral Emmely Vitória Santana , Xavier Bárbara Victória Vieira Ribeiro , Sousa Adna Cristina Barbosa de , Almeida Andréa Farias de
Published: November 2024

Objetivo: Avaliar a produção de enzimas celulolíticas e proteolíticas a partir de Aspergillus sp NA01 e Paecilomyces sp.TP08 utilizando o engaço de uva como substrato em fermentação em estado sólido.
Referencial Teórico: O processamento de uva para produção de vinhos gera resíduos, como: engaço, casca, semente e bagaço, que são geralmente descartados de forma inadequada.
Método: O engaço foi caracterizado quanto à sua umidade, pH, porosidade e açúcares redutores totais. Para produção enzimática, foi utilizado frascos erlenmeyers com 5g de engaço de uva inoculados com Aspergillus sp NA01 e Paecilomyces sp.TP08 (1x107 conídios/g, 70% umidade e 30 °C). Após 10 dias de inoculação, foi extraído o complexo enzimático para determinação da atividade enzimática.
 Resultados e Discussão: O engaço caracterizado tinha 70% de umidade, pH 4, porosidade de 0,39 g/mL e açúcares redutores totais (1,00g/L). Após 10 dias de processo, atividade celulolítica a partir do isolado Paecilomyces sp. TP08 foi de 7,48U/g para CMCase, 2,11 U/g para FPase e proteolítica de 26,39 U/g, e para o isolado Aspergillus sp. NA01 foi de 11,41U/g para CMCases, 1,73 U/g para FPases e 8,17 U/g para proteases.
 Implicações da Pesquisa: Diante dos resultados, foi verificado o potencial da utilização do engaço de uva para produção de enzimas microbianas, principalmente enzimas celulolíticas e proteolíticas.
 Originalidade/Valor: O enfoque na utilização de resíduos agrícolas como substrato para a produção de enzimas representa uma abordagem inovadora que contribui para a valorização de subprodutos agroindustriais, promovendo a sustentabilidade. A alta atividade celulolítica e proteolítica observada pode levar ao desenvolvimento de processos mais eficientes e economicamente viáveis, sendo relevante para a indústria.
Development of a Continuous Glucose Monitoring Service by Clinical Pharmacists in a Medically Underserved Population
Authors: Lingow Sara , Kinnikin Kacie , Guyton Justinne
Published: November 2024

Background: Continuous glucose monitoring (CGM) is an evolving technology that provides a wealth of information to aid in managing diabetes. Professional CGM (ProCGM) is recommended when personal CGM is not desired or available. Patients in medically underserved areas may have limited access to personal CGM devices, thus ProCGM devices can be used for short-term monitoring and medication adjustment. Clinical pharmacists are well-positioned to help set up and establish personal and professional CGM management services.
Objectives: To determine the effect of ProCGM in patients with persistently uncontrolled type 2 diabetes in a medically underserved population (MUP).
Methods: Pre-post intervention analysis of a single cohort of patients in a public health center. Patients with persistently uncontrolled (A1c > 9%) and taking at least one daily dose of insulin were included. Included participants wore a ProCGM sensor and met with the clinical pharmacist at least once for ProCGM data interpretation and education. The primary analysis evaluated patients who achieved an A1c <9%  1-6 months after intervention. The change in A1c was also evaluated. Participants completed a pre- and post-survey about their experience.
Results: Twenty-two patients were included in the final analysis. Ten patients achieved an A1c <9% (45%). The mean A1c pre- and post-ProCGM was 11.0% and 9.8% respectively, with a decrease of -1.2% (p=0.055) overall and a decrease of -1.7% for patients who wore the sensor for at least 10 days (p=0.012; n=15). Using the CGM data 91% of participants had a change to their medication regimen and 45% achieved an A1c <9%. Six participants experienced hypoglycemia per the CGM report, but only two were aware of it. After reviewing their glucose report with the pharmacist, 95% of the respondents agreed or strongly agreed to feeling more knowledgeable about blood sugar patterns after reviewing the report with a pharmacist.
Conclusion: Almost half of the patients in the study achieved an A1c <9%. This study demonstrated glycemic benefit in patients in a MUP who wore a ProCGM for at least 10 days and met with a clinical pharmacist. Data from ProCGM enabled patients to better understand glucose patterns in those with persistently uncontrolled type 2 diabetes.
Prevalence, Scope and Quality of Extemporaneous Medications in Selected Healthcare Facilities and Implications for Pharmacy Practice
Authors: Allotey-Babington Grace Lovia , Kretchy Irene Akwo , Asiedu Esther Atiapa , Amuakwa Maxine Kelly , Seaneke Obedia Akwele , Ankrah Daniel , Somuah Abredu Kwadwo , Owusu-Nyamekye Agatha Dei , Owusu-Ansah Sarah , Effah Patrick Kwame , Debrah Johnson , Nai Edna Acheampomaa , Owusu Emmanuel , Lamptey William , Asiedu-Gyekye Isaac Julius , Nettey Henry
Published: November 2024

Background: Extemporaneous compounding is the preparation of medicines for individual patients when no commercially available authorized form exists. Unlike registered medications, these products are not subjected to various tests for quality by Regulatory Authorities. Data on compounded medications in Ghana is currently inadequate or unavailable. There is the need to collate data that can be used to influence policy and to regulate preparation of extemporaneous products.
Aim: To establish the prevalence, scope and quality of extemporaneously compounded medicines at selected hospitals in Accra, Ghana.
Methodology: Prescriptions presented at the pharmacies in selected hospitals were reviewed to determine the requests that needed to be extemporaneously prepared as well as the prevalence and the scope of formulations. Three of the most frequently compounded medications were procured and subjected to microbial contamination tests using the pour plate method followed by differential tests if microbes were present. Content analysis of the active ingredients was determined using High Performance Liquid Chromatography (HPLC).
Results: 641 requests comprising 49 different extemporaneous products were collated from the hospitals studied. Hydroxyurea, furosemide and spironolactone suspensions were the three most frequently prescribed. Patients aged from 0-2 years had majority of the prescriptions.
Conclusion: A population of patients still exist who depend on compounding for their drug needs. 49 different formulations were prepared at one of the hospitals visited. Samples of products analyzed were of good quality.
Using a Preceptor Development Series in Writing and Publication to Improve Residency Research Manuscripts
Authors: Longyhore Daniel , Wright Eric , Krahe-Dombrowski Sarah , Andrick Benjamin
Published: November 2024

Description of the Problem: Rates of pharmacy residency research projects making it to peer review and publication are low (between two and seven percent).  Little is known about the influence of preceptor development on moving projects to peer-review and publication. 
The Innovation: The primary objective was to describe the effect of a preceptor development series on writing and overall manuscript quality leading to submission to a peer-reviewed publisher.  Three pharmacy preceptors assigned to a post-graduate year 1 residency project were enrolled in a six-week series focused on writing, peer-reviewed publishing, and advancing resident research to publication.  Each preceptor was tasked with implementing development series content in their resident research mentorship. 
Critical Analysis: Resident project manuscripts were assessed using a previously published 34-item evaluation tool.  All papers were blinded for independent evaluation by two investigators.  Nine papers were evaluated: three from preceptors who participated in the development program and six from preceptors who did not participate.  The mean summary scores for papers with preceptors who participated versus those who did not were 5.8 and 5.4, respectively, on a 10-point scale.  Additionally, papers from preceptor participants were noted to achieve satisfactory scores on evaluation tool items 85.3% of the time versus 74.7% of the time for non-participants. 
Next Steps: Participation in a six-week preceptor development program on advancing resident writing and research to publication provided preceptors the tools needed to mentor higher quality manuscripts ready for publication.  Residency programs may consider designing and implementing such a series to promote preceptor and resident research publication.
Modifying Pharmacy Enrollments by Employment Realities
Authors: Lloyd Crystal , Wertheimer Albert , Bissasor Thandeka , Truong Phat , Khanfar Nile
Published: November 2024

Objective: The objective of this commentary is to consider the fluctuations in pharmacy school enrollments and to review some of the strategies employed in other health care professions as well as to consider policies that might lead to a closer balance between admissions to PharmD programs and employment opportunities.  Such a balance provides superior job stability, decreased underemployment, and greater attractiveness to study pharmacy.
Findings: Pharmacy school entry requirements and standards have been relaxed to accommodate as many students as possible due to current declining applicant numbers. As a result, there are more pharmacist graduates than there are available jobs each year to the point that the job outlook for pharmacists may continue to go down in the future unless something is done to address the problem.  Stricter entry requirements could help produce a higher quality pharmacy workforce in the future and relieve this disparity.
Summary: Pharmacy schools try to accommodate as many students as possible creating a job disparity between the number of available jobs and pharmacists seeking work. Suggestions can include stricter entry requirements, a certificate of need-type program, and other means to balance this misalignment.
Leadership and Followership in Health Professions: A Systematic Review
Authors: Gallegos Patrick , Riaz Muhammad Salaar , Peeters Michael
Published: November 2024

Objective: Leadership discussion, including leadership development programs, is common. However, discussion of followership as a component of leadership seems less frequently discussed. With a focus on leadership and followership, this investigation reviewed the health-professions education literature and characterized leadership-followership within health-professions education.
Methods: Using PubMed, ERIC, and Google Scholar, two investigators independently and systematically searched health-professions education literature for articles related to leadership and followership. Reports were categorized based on the articles by type, application, profession, leadership, and followership qualities.
Results: Eighty-one articles were included. More than half (48/81, 59%) were theoretical, 27% (22/81) empirical, 7% (6/81) commentaries, and 6% (5/81) letters-to-the-editor). Empirical studies did not share outcomes that could be meaningfully combined quantitatively by meta-analysis; however, the vast majority (96%) of theoretical articles discussed a healthcare-related application of leadership and followership (e.g., improving patient care, improving communication, improving organizational efficiency). Thus, a qualitative review was completed. Of the 81 articles, 57% (n=46) involved multiple professions, while 43% (n=35) focused on a specific profession [Nursing (n=16), Medicine (n=7), Others (n=5) Surgery (n=3), Pharmacy (n=2), Veterinary Medicine (n=2)]. While most articles (75%) discussed leadership qualities (with top qualities of effective communication, visionary, and delegating tasks), fewer (57%) discussed followership qualities (with top qualities of being responsible, committed, and supportive). Of note, some qualities overlapped in both leadership and followership (with top qualities of effective communication, being supportive, and providing/receiving feedback).
Conclusions: Leadership-Followership was described in many health-professions’ education literature. However, Pharmacy and Veterinary Medicine had substantially fewer articles published on this topic. Notably, followership did not receive nearly as much attention as leadership. Leadership has a dynamic and complex interaction with followership highlighting that an effective leader must know how to be an effective follower and vice versa. To improve leadership within healthcare teamwork, education should focus on both leadership-followership.
Diagnosis and Management of Daptomycin-Induced Acute Eosinophilic Pneumonia: A Case Report
Authors: Elbarbry Fawzy , Farthing Kate , Arguello Shannon
Published: November 2024

Daptomycin is a cyclic lipopeptide antibiotic that is indicated for the treatment of complicated skin infections and bacteremia caused by gram positive organisms. Acute eosinophilic pneumonia (AEP) is a rare, but serious adverse effect of daptomycin and caused by accumulation of eosinophils in the lung tissues, and can lead to respiratory failure. Early diagnosis and management of this condition is crucial to avoid severe complications, including death. Herein, we report a case of an elderly man who presented with signs and symptoms of AEP within two weeks of initiation of daptomycin for the treatment of MRSA bacteremia. The patient showed significant clinical improvement and decline in eosinophils upon discontinuation of daptomycin and starting a 5-day steroid course. Acute eosinophilic pneumonia should be kept in mind as a possible, although rare, adverse effect of daptomycin. Early recognition can be established through typical symptoms, eosinophilia, and chest X-ray showing pulmonary infiltrate. Rapid discontinuation of daptomycin with/without steroid therapy and supportive care usually results in significant clinical recover.
A Retrospective Review on HIV Pre-Exposure Prophylaxis in Davao City
Authors: Ebe Angel Mae A. , Gucila Chriszle Anne T. , Esponilla Aj G. , Canja Jayson B. , Gabucan Von Jay Maico G.
Published: November 2024

Objectives: Evaluating the adherence to HIV Pre-Exposure Prophylaxis (PrEP) is essential for increasing its utilization and decreasing the risk of HIV transmission among Davao City's vulnerable groups.
Methods: The research method utilized in the study is a quantitative, retrospective, descriptive research design. This method was employed to retrospectively review the de-identified data, which involved the fill and refill dates of PrEP and tablets supplied, to calculate the Proportion of Days Covered (PDC) among individuals in Davao City from January 2021 to December 2023. The study also included some demographic characteristics such as age and gender.
Results:   From 178 data entries collected, the age group of 25 to 34 years old was found to have the highest HIV PrEP use (52.3%), followed by those between 18 to 24 (30.9%), 35 to 44 (13.5%), and 45 years old and older (3.4%). Out of 178, only 2 clients were female. Furthermore, 73.6% of the 178 entries in the pharmacy records were identified to be taking PrEP daily. Descriptive statistics showed that the frequency of adherent clients across the years were 36.4%, 44.7% and 38.5%, respectively. Furthermore, the average PDC through the years was found to be 70.13%, 80.48%, and 72.8%. Age did not significantly affect adherence to PrEP during the years investigated (p-values > 0.05). 
Conclusion: Adherence to PrEP improved consistently in 2022 but declined in 2023, showing erratic adherence rates. Furthermore, adherence to HIV PrEP in Davao City was found to be suboptimal and while there are clients who are adherent, many are not. The results emphasize the need for targeted interventions and suggest that other socio-behavioral factors may play a role in this. To improve adherence and prevent HIV contractions, both short-term actions like public education campaigns about HIV PrEP and long-term plans like incorporating PrEP into the community pharmacies can be contributive.
Assessment of Metformin Intolerance: A Retrospective Chart Review
Authors: Murphy Pilar , Bramwell-Shittu Alanna , Boehmer Kaci , Painter Jacob , Mahashabde Ruchira
Published: November 2024

Objective: The aim of the present study is to determine similarities between patients with type 2 diabetes not on metformin therapy compared to patients on metformin therapy at a resident-led primary care clinic. Methods: An exploratory, single-center retrospective chart review was performed on patients 18 years and older with a documented diagnosis of type 2 diabetes seen at the University of Arkansas for Medical Sciences Family Medicine Clinic in Little Rock, Arkansas. Of the 2452 patients who met criteria for the study, 1085 patients did not have a documented metformin allergy. A subset of 216 patients who were not currently prescribed metformin and had no documented metformin allergy were further examined and compared to the 869 patients who were prescribed metformin. We sought to determine reasons for nonuse by evaluating their EPIC electronic health record. Information on these patients such as race, gender, hemoglobin A1c (A1c), kidney function, stated metformin intolerance, and comorbid disease states such as neuropathy, chronic kidney disease (CKD), ulcerative colitis, and irritable bowel syndrome were collected. Further examination was performed to determine why patients were not on metformin therapy and potential similarities between metformin intolerant patients. Results: The results of the study indicated a significant difference between metformin users and non-users in relation to body mass index (BMI) and diagnosis of CKD. Metformin non-users were found to have significantly lower mean BMI (30.87 vs. 35.43; p-value <0.0001), and significantly higher rates of CKD (25.93% vs 14.73%; p-value <0.0001) as compared to metformin users. BMI value of patients (coefficient: 0.2033, p value: <0.0001) was found to be significantly and positively correlated with metformin use, and CKD (coefficient: - 0.1191, p-value: <0.0001) was found to be significantly and negatively correlated with metformin use. A1c levels for patients not on metformin therapy were evaluated. Most non-metformin patients fell in prediabetic A1c levels ranging from 5-6.4% (84 patients; 38.89%), and 31 patients (14.35%) should be on insulin therapy according to guidelines. Conclusion: The results demonstrated that patients with lower BMI, CKD, or A1c in the prediabetic range were less likely to be prescribed metformin.