bluuebunny/crossref_metadata_2025 huggingface dataset:
Daya Terima Modifikasi Ikan Sarden dan Sayur Bayam pada Dimsum Sebagai Makanan Tambahan Tinggi Kalsium
Authors: Rotua Manuntun , Putri Sesiel K , Podojoyo Podojoyo , Sriwiyanti Sriwiyanti
Published: August 2023

Osteoporosis is a bone disease characterized by a decrease in bone density which causes bones to become brittle, bone conditions deteriorate where bone pores are porous. According to data from the Indonesian Ministry of Health, the prevalence of osteoporosis in 2016 there were 3,385 people who came to puskesmas with cases of Osteoporosis, consisting of 1,115 in men and 2,270 cases in women. From data from the Palembang City Health Office in 2017, there were 112 people who came to the South Sumatra Health Center with cases of osteoporosis, consisting of 37 men and 75 women. Strategies to overcome the problem by consuming foods that are high in calcium, such as milk, sardines, salmon, fish eaten with their bones (anchovies), soy-based foods, fruits, and green vegetables.  The study was conducted using a non-factorial complete randomized design (RAL), using 30 untrained panelists. Acceptability is carried out by organoleptic tests. The results of the organoleptic test of dimsum selected in the F1 formulation (150 grams of sardines and 25 grams of spinach), the results of the acceptability test obtained an average color value of 3,567, aroma of 3.07, taste of 3.87, and texture of 3.47. The results of proximate analysis obtained an energy content of 203.74 kcal, protein 8.75%, fat, 1.82%, carbohydrates 38.09%, and calcium 96.42 mg.
TO STUDY THE EXPRESSION OF E-CADHERIN AND VIMENTIN IN PRECANCEROUS AND CANCEROUS LESIONS OF ORAL CAVITY
Authors: Verma Deepak , Harsh Meena , Hodkasia Kalpana
Published: August 2023

Background: The aim today is early detection of cancer and prevention of progression for a better prognosis. In this respect various markers have received attention. This study was done to evaluate the role of E-cadherin and Vimentin in early detection of cancer. It may predict tumor behavior and micro invasion, and thus the prognosis which will help in better treatment and increase patient survival. Methodology: The study was conducted over a 12-month period and comprised 40 patients of oral cavity lesions. Microscopic examination was done and morphological ndings were noted. After histopathological diagnosis, sections from tumor were selected for staining E-cadherin and Vimentin using standard procedures. Results: Maximum number of patients (35%) were in the age group of 51 to 60 years. Majority of the patients were males (77.5%).12 were premalignant lesions and 28 cases were different grades of squamous carcinoma. Buccal mucosa was the commonest site involved. Ecadherin expression was shown to be higher in premalignant lesions as the degree of dysplasia rose. Vimentin staining showed decrease in expression with increase of histological grade in some cases. Conclusion: E-cadherin and vimentin, when combined, can be employed as key indicators of premalignant and cancerous oropharyngeal lesions. They predict the histological grade and suggest prognostic outcome
A STUDY TO EVALUATE THE PREDICTORS OF DIABETIC PERIPHERAL NEUROPATHY AND UTILITY OF MICHIGHAN NEUROPATHY SCREENING INSTRUMENT AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS
Authors: Amruthavarshini Amruthavarshini , V. S Sheshan , M Ramesh , Madhumathi Madhumathi
Published: August 2023

Background and Objective: Diabetic neuropathy signicantly lowers the quality of life. The objective of study is to assess the predictors of
peripheral neuropathy in patients with type 2 Diabetes Mellitus attending diabetes clinic and to evaluate the sensitivity and specicity of Michigan
Neuropathy Screening Instrument considering neurothesiometer as standard. Methods: In 110 type 2 diabetic patents attending diabetic clinic in
Bangalore Medical and Research institute , a cross sectional study conducted where they are screened for diabetic peripheral neuropathy using
Michighan Neuropathy Screening Instrument and compared with Neurothesiometer as standard which is further compared to patient's duration of
diabetes, treatment modality and glycemic control. Results: Overall the prevalence of diabetic peripheral neuropathy in this study was 51.8 %
using the neurothesiometer as standard, large bre neuropathy in 43.8 %, small bre neuropathy in 24.5% and both in 31.5%. Of total 51.8%
patients with neuropathy 59.6 % have mild neuropathy, 19.2% have moderate and 21.2 % have severe neuropathy. The Michigan Neuropathy
Screening Instrument (MNSI) is found to have Sensitivity of 91%, Specicity of 60%, PPV of 71%, NPV of 86% and Accuracy 76% Conclusion:
The study shows that a signicant association is found between age of patient, duration of diabetes, glycemic control (HbA1c), BMI and Diabetic
peripheral neuropathy. With accuracy of Michigan Neuropathy Screening Instrument 76 % is helpful to detect peripheral neuropathy in initial
stages in clinical settings, in a simple and cost effective manner
MORPHOLOGICAL CHANGES IN THE PLACENTAE OF HYPERTENSIVE DISORDERS OF PREGNANCY IN MEWAT REGION OF HARYANA.
Authors: N Raghvi , Mehrotra Namita , Arora Neetu , Mangla Divya
Published: August 2023

Background:In India, there are many regions with increased rate of reproduction and poor fetal outcome. One of the most common complications
of pregnancy in these regions are Hypertensive disorders of pregnancy. The morphology of the placenta reects the status of severity of maternal
hypertension which might affect the fetal outcome. Aim: The study objective was to evaluate and contrast the placental morphological alteration in
the placentae from mothers having hypertensive disorders of pregnancy(HDOP) in comparison to placentae from normotensive pregnancies.
Material and Methods: An observational case control Study was performed. 50 placentae from Normotensive mothers (control group) and 50
placentae from hypertensive mothers (case group) were collected from Obs and Gynae department of a tertiary care hospital. Results:It was found
that the placenta in hypertensive women in comparison to normotensive women have low placental weight, less maximum diameter, less Surface
area, reduced placental volume, paracentral umbilical cord, and a smaller number of cotyledons, increased retroplacental colts. The differences
between the groups were statistically signicant (p<0.05). Statistically signicant (p 0.05) differences existed between the groups Conclusion:
According to the ndings of the current study, the placenta obtained from women with hypertensive disorders of pregnancy show signicant
morphological changes that may lead to impaired fetoplacental circulation. This can lead to adverse fetal outcomes.
A PROSPECTIVE STUDY OF CLINICAL PHENOTYPE DIRECTED MANAGEMENT OF BLADDER PAIN SYNDROME /INTERSTITIAL CYSTITIS (BPS / IC)
Authors: Kumar Asari Ashish , Vijayanand Potdar Ojas , Pandey Sanjay , Khandekar Archan , Badlani Naresh , Iqbal Lone Yasir , Singh Akhalesh , Vikram Patkar Amrita
Published: August 2023

Aims and Objectives:
Primary Objective
Ÿ To classify patients with Bladder Pain Syndrome/IC using clinical phenotype system using UPOINTclassication system.
Ÿ To assess a therapeutic strategy for patients of interstitial cystitis/ bladder pain syndrome (IC/BPS) using an individualized phenotype-directed
treatment plan based on clinically based categorization.
Secondary Objective
Ÿ To stratify the response after the treatment using O'Leary-Sant ICSI /ICPI questionnaire scores on clinical scale.
Materials and Methods:
It was a prospective observational hospital-based study where patients diagnosed with IC/BPS aged 18 years or older were considered in this study
excluding all confusable diseases. All the patients according to their symptomatology, reports and clinical phenotype were classied into UPOINT
system. All patients received treatment which were directed as per UPOINT system and O'Leary-Sant ICSI /ICPI questionnaire scores were
collected as responses were achieved at 1 week, 1 month and 2 months of follow up. Results: Follow-up visit data were available for 52 patients
mean age, 54.6±12.9 years and mean ICSI/ICPI, 23±3). Patients reported UPOINT domains with the following distribution: Urinary - 100%;
Psychological – 73.1 %; Organic -100 %; Infection – 26.9 %; Neurogenic/Systemic- 55.8 %; and Tendernes- 25 %. The mean decrease in ICSI was
11±3 points. Signicant clinical improvement (>30%-50% decrease in ICSI-26.9 and >50 % decrease in ICSI- 63.5 %) was observed in 91.4 %
compared with initial baseline visit. Signicant improvement was seen after UPOINT directed treatment with the symptoms of IC/BPS.
Conclusion: Patients referred to a tertiary IC/BPS clinic, regardless of the complexity or severity of condition, experienced clinically signicant
improvement using an individualized UPOINTclinical phenotype-directed therapeutic approach.
SENSITIVITY AND SPECIFICITY OF DISTRESS THERMOMETER FOR DETECTING DEPRESSION AMONG PATIENTS DIAGNOSED WITH MAJOR DEPRESSIVE DISORDER
Authors: Mary John Anju , Babu Mili , Sivasubramoney Krishnan
Published: August 2023

Introduction: By 2030, depression is anticipated to be a major contributor to the global illness burden. The most prevalent psychiatric condition
documented in community settings in India is depression and remains unidentied in primary care. Over the previous few decades, an increase in
the prevalence of depression has been noted and therefore it is crucial to identify those who are depressed and to intervene as soon as feasible.
Objectives: The current study primarily aims to estimate the sensitivity and specicity of the distress thermometer for detecting depression among
patients diagnosed with major depressive disorder. The study also attempts to nd out the correlation between the distress thermometer score and
PHQ-9 score. Methods: Atertiary centre based cross sectional study was carried out among 600 adult persons. After obtaining Informed Consent,
Sociodemographic and clinical details were recorded using semi structured questionnaire. Each patient's level of distress was assessed using
Distress Thermometer questionnaire and the level of depressive symptoms was assessed using PHQ-9 questionnaire. Spearman correlation
coefcient was used to nd the correlation between the two scores. Results:Acut-off score of 4 represents the optimal cut-off with sensitivity and
specicity 82.3%% and 79.7% respectively. Current study showed positive correlation of distress thermometer score with PHQ-9 score.
Conclusion: The single-item DT performs satisfactorily, with an optimal cut-off of 4 (sensitivity =82.3%, specicity =79.7%,) compared to the
DSM 5 for identifying depression among patients diagnosed with major depressive disorder.
ETIOLOGICAL PROFILE OF TROPICAL DISEASES IN ACUTE FEBRILE ILLNESS PATIENTS AND DETERMINE THEIR CLINICAL FINDINGS.
Authors: Pranjal Pranjal , Bansal Nitin
Published: August 2023

Introduction: Tropical diseases are prevalent in regions between the Tropic of Cancer and the Tropic of Capricorn due to favorable conditions for pathogen growth. Factors such as poverty and poor living conditions contribute to their higher prevalence. Increased connectivity has led to the spread of tropical infections to new areas. Fever is the common initial symptom, and respiratory complications have been observed, especially during the COVID-19 pandemic. Aim and Objective: This study aimed to identify the etiological and clinical prole of patients with acute febrile illness and tropical infections in Uttarakhand, India. The objective was to study the etiological prole of tropical diseases and determine their clinical and laboratory ndings. Materials and Methods: The study was conducted at Shri Mahant Indresh Hospital, SGRRIM&HS Dehradun, from July 2021 to December 2022. Adult patients with fever lasting 2-14 days and no specic foci of infection were included. Ethical approval and written informed consent were obtained. Data on symptoms, signs, and relevant parameters were recorded using a study proforma. Results: The study included 100 patients with a mean age of 39.86 ± 16.3 years. The most common symptoms were fever, headache, myalgia, and arthralgia. Dengue was observed in 41% of cases, followed by scrub typhus (14%), typhoid (12%), malaria (12%), chikungunya (9%), and mixed infections (6%). Six cases remained undiagnosed. Conclusion: Dengue was the most common tropical disease in Uttarakhand, followed by scrub typhus, typhoid, malaria, and chikungunya. Fever was the predominant symptom. Clinical investigations are crucial for diagnosis, and the deranged clinical and laboratory prole may indicate severe infection or complications requiring intensive care and appropriate management.
A STUDY OF CLINICAL, RADIOLOGICAL PROFILE OF CEREBRAL SINUS VENOUS THROMBOSIS (CSVT) PATIENTS AND CORRELATION OF THEIR OUTCOME WITH CSVT SCORE
Authors: Akhilesh Kumar N. , Veena N. , Sudarshan Reddy P.
Published: August 2023

Background & Objectives Cerebral sinus venous thrombosis (CSVT) is a potentially fatal neurological condition that can be frequently overlooked due to the vague nature of its clinical and radiological presentation. Extent of cerebral sinus venous thrombosis (CSVT) may determine clinical severity, magnetic resonance imaging (MRI) lesion and outcome. This study was undertaken to analyze the relationship between extent of sinus thrombosis and outcome. To study the clinical, radiological prole of Cerebral Objectives: Venous Sinus Thrombosis. To calculate the CSVT Score and their correlation with outcome at discharge, 3 months and 6 months. It Methods: was an prospective observational study in patients of Cerebral Venous Sinus Thrombosis. After taking informed consent, detailed history was taken and examination was done. 90 Patients Results: with CSVT were included in the study. Age ranged between 17 and 60 years, 48 (53.3%) were females. Majority of them (56) had subacute presentation. Most common sinus involved was transverse sinus in 70 cases (77.8%). Median CVST score was 4 (range 1 – 7). CVST scores correlated well with duration of onset of symptoms, seizure, level of consciousness at presentation, outcome at discharge. CVST scores did not correlate with gender, papilledema, neurological decits, outcome at 3 months and 6 months. Supercial venous system thrombosis correlated with seizure, level of consciousness, parenchymal lesion and did not correlate with gender, raised ICP. Extent of sinus involvement Conclusions: correlated with duration of onset of symptoms, seizure, level of consciousness at presentation, outcome at discharge. But did not correlate with gender, papilledema, neurological decits, outcome at 3 months and 6 months.
STUDY ON PREVALENCE OF POST - COVID LUNG SEQUELAE AND CLINICORADIOLOGICAL PROFILE OF POST- COVID PATIENTS IN TMC & DR BRAM TEACHING HOSPITAL
Authors: Das Anamika , Saha Soma , Prakash Bhaumik Dipankar , Reang Chandini
Published: August 2023

Background: Post-COVID lung sequelae can present with a range of symptoms, such as shortness of breath, cough, fatigue, joint pain and chest
pain. This adds to the burden of the disease and thus needs a descriptive analysis in a region-specic manner in India. Methodology: Patients were
assessed based on the clinical manifestation by the physician as well as by the use of preformed questionnaire, pulse oximetry and chest CT scan.
Results: The majority (63.8%) of study patients experienced shortness of breath (SOB), followed by cough and fever, while Ground-glass opacity
(GGO), followed by brotic band and consolidation, predominated in clinico-radiological imaging. However, statistical test didn't show any
signicant association of the risk factor with radiological nding, perhaps due to a smaller sample size. Conclusion: Monitoring post-COVID 19
lung sequalae in bigger cohorts over extended period of time will be important for further scientic development.
VOLUME OF PLASTICS AMONG BIOMEDICAL WASTE GENERATED IN AN INDIAN HEALTHCARE FACILITY: THE HIDDEN BURDEN
Authors: Dutt Bhardwaj Nitin , Jain Anmol , Srivastava Kirti , Srivastava Pradeep , Agarwal Kris
Published: August 2023

Background- Bio-medical waste includes waste generated during medical activities, with proper management being crucial for health and the
environment. Hospital waste consists mostly of non-hazardous waste, but a portion is infectious and hazardous. Plastic waste in healthcare is a
signicant issue, and efforts should be made to reduce its use. The objective of this research study is to investigate plastic usage in Indian hospitals
and promote practices that minimize negative impacts. The study was c Methodology: onducted at a Tertiary Care Government University using a
cross-sectional and descriptive study design. The inclusion criteria encompassed all solid waste generated in specic areas, while liquid waste was
excluded. Waste was categorized according to the BMW 2018 Amendment Rules. The variables of interest included assessing the total amount of
waste in different categories and segregating plastics and non-plastics. Data was collected using an assessment toolkit and analyzed with
appropriate statistical techniques. The ndings showed that 80.7% of the waste Results- generated during the study period was general waste,
while 19.3% was biomedical waste. The largest portion of biomedical waste was categorized as Red waste (10.4%), followed by Yellow waste
(6.3%), Blue waste (2.4%) and White waste (0.13%). A segregation process was carried out to analyse the plastics present in the waste collected.
The results showed that only 13% of general waste and 18% of biomedical waste consisted of plastic materials. The study's results Conclusionseeks to address plastic waste in healthcare and empower professionals to reduce plastic consumption for the benet of the environment and public health.
EVALUATION OF HYSTEROSCOPIC FINDINGS IN INFERTILE WOMEN AND ITS CORRELATION WITH SUBSEQUENT IMPLANTATION RATE: A RETROSPECTIVE STUDY AT TERTIARY CARE HOSPITAL
Authors: Bhati Salvi Meena , V Bhat Vidya
Published: August 2023

Background: Hysteroscopy offers diagnostic accuracy and the ability to treat uterine pathology simultaneously. Our aim is to evaluate the hysteroscopic ndings in women with primary or secondary infertility and to assess their subsequent implantation rate after correction in one year of follow up period. Methods: Aretrospective and descriptive study was conducted on 153 women with history of primary or secondary infertility over a period of one year from January to December 2019 and follow up was done till next 1 year at Radhakrishna multispeciality hospital and IVF Centre, Bangalore, Karnataka. All 153 women underwent hysteroscopy either diagnostic or operative wherever indicated, to evaluate the cervical and uterine pathologies. Normal and abnormal ndings were noted and analysed. Incidence of normal and abnormal hysteroscopic ndings and subsequent implantation rate were assessed till next one year. Reproductive outcome were evaluated in the forms of spontaneous pregnancy, ovulation induction, IUI or IVF pregnancy. Results: Out of 153 patients, 87 (56.86 %) patients had abnormal ndings. The majority of which was identied as endometrial polyps. Others were hyperplastic endometrium, myoma, septum, adhesions and endometritis. Total 34 (22.22 %) out of 153 women became pregnant following hysteroscopy. 22 pregnancies, (25.28% ) occurred in women with corrected endometrial pathology after abnormal ndings. Out of 22 pregnancies, 12 women conceived spontaneously, 9 women after ovulation induction, 1 after IUI . Conclusions: hysteroscopy improved the implantation rate. Hysteroscopy and appropriate therapy signicantly increased the chances of achieving a subsequent pregnancy
IDH1R132H GENE-A DIAGNOSTIC AND PROGNOSTIC MARKER IN GLIOMAS
Authors: Kaul Vidya , S Rajmohan K
Published: August 2023

Aim: To study the frequency of Isocitrate dehydrogenase1 R132H [IDH1R132H] gene mutations in phenotypic lobar gliomas by Immuno
histochemistry [IHC] and establish R-132H as a prognostic and diagnostic marker in gliomas. This study was a Material and method:
Bidirectional correlative study on the clinical, pathological, and molecular characteristics of adult gliomas, carried out in the Dept of Laboratory
sciences at Base Hospital, Delhi Cantt-110010.All consecutive (optd) cases of gliomas from 2015 to 2018 were included Immunohistochemistry
was used to detect IDH1-R132H instead of sequencing, aiming to provide a mature and simple tool for clinical practice. In the light of the “ISNHaarlem” consensus, the routine approach to all diffuse astrocytic and oligodendroglial gliomas begins with performing IHC for IDH1-R132H
expression. A negative control, in which the primary antibody was excluded was incorpora Results: ted with each batch of staining. Staining
intensity was graded as +2 (strong positive staining), +1 (weak positive staining) & 0 (negative/ no staining). In our study only a staining intensity
of +2 ie., strong positive staining was considered to label the tumour for the biomarkers studied. The labeling index (LI) for IDH1R132H to be
labeled as positive was > 10% and the tumor was considered negative for IDH1R132H if the Labeling index was <10%. It was Conclusion:
concluded that the IDH1-R132H is necessary to provide the basic molecular information for the “integrated diagnosis” of gliomas
DETERMINING TESTICULAR STIFFNESS VALUES USING SHEAR WAVE ELASTOGRAPHY IN 36 HEALTHY INDIVIDUALS -A CROSS SECTIONAL STUDY.
Authors: N Ravi , Mouna R Mohit , H Vinutha , Begum Naseema , Kavya Kavya , R Malkhedkar Darshan
Published: August 2023

As a relatively new sonographic technique, tissue elastography has emerged as a qualitative and potentially quantitative adjunctive tool to provide additional information on tissue stiffness, aiming to further improve diagnostic condence in discriminating benign from malignant focal testicular lesions. To establish normal range of Shear Wave Elastography values of different Aim and objective: regions of testes measured in terms of kilopascals (kPa) in 36 healthy individuals and to compare Shear wave velocity differences at these various regions of testes. A total Methodology: of 36 subjects were divided according to their age into three groups (20-30, 30-40 and >41 years), all the subjects underwent examination of bilateral testes (72 testes in total) using Grey Scale Ultrasonography followed by Shear wave elastography and shear wave velocity of different regions of testes (Upper, Mid, Lower poles, Upper periphery and Lower periphery) measured in terms of kilo pascals (kPa). On Right, the Result: Mean Shear Wave Elastography (kPa) values at the Lower periphery (Group A) and Lower pole (Group B) and Group C (Consisting of Upper pole, Mid pole and Upper periphery) were signicantly different and On Left, the Mean Shear Wave Elastography (kPa) values at the Lower periphery (Group A) was signicantly different from Group B (Consisting of Upper pole, Mid pole, Lower pole and Upper periphery). Conclusion: Incorporating use of Strain or shear wave elastography techniques along with Grey scale ultrasonography and Color doppler in the evaluation of testes serves as part of a multiparametric ultrasound examination which is indispensable for increasing diagnostic accuracy in testicular pathology. Hence knowledge of normal shear wave velocity values at different regions of testes is important before interpreting the pathological conditions in order to void potential pitfalls
CORRELATION OF DURATION OF DIABETES MELLITUS AND GLYCOSYLATED HAEMOGLOBIN (HBA1C) LEVELS WITH DIABETIC RETINOPATHY
Authors: Mujumdar Deepti , Varma Pushpa , Rai Parth
Published: August 2023

Purpose - To correlate the duration of diabetes mellitus and glycosylated haemoglobin (HbA1c) levels with grades of diabetic retinopathy
Material & method- An observational cross-sectional clinical study was conducted involving 100 diabetics. Detailed ophthalmic evaluation was
done and data involving fasting blood sugar levels, post prandial blood sugar levels and glycosylated haemoglobin levels were collected. Any
diabetic retinopathy related changes were documented & grading was done on the basis of severity using ETDRS classication. Out of 100 Resultdiabetic patients evaluated, 58% patients had diabetic retinopathy (DR). There was no gender predilection. Strong association was found between
duration of diabetes mellitus with presence & severity of Diabetic retinopathy. Chances of a diabetic patient developing DR & progression of DR
increases as the duration of diabetes increases. Positive association was found between poor glycemic control as established by HbA1c levels with
presence & severity of DR. Higher the HbA1c levels, higher the risk for DR. It wa Conclusion- s concluded that in diabetic patients, good glycemic
control reduces the occurrence & progression of diabetic retinopathy.
SALIVARY GLAND NEOPLASMS – AN INSTITUTIONAL EXPERIENCE
Authors: Kumar Dhivya , Kawarat Vikas , Kamalraj M. , S. Shanthi P.
Published: August 2023

Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle
in their management lies in the difculty in distinguishing benign from malignant tumours. Investigations such as ne needle aspiration cytology and
MRI scans provide some useful information, but most cases will require surgical excision as a means of coming to a denitive diagnosis. Benign
tumours and early low-grade malignancies can be adequately treated with surgery alone, while more advanced and high-grade tumours with regional
lymph node metastasis will require postoperative radiotherapy. The role of chemotherapy remains largely palliative. This paper aims to study the
clinico-epidemiological pattern, histological subtypes, management and postoperative complications of salivary gland neoplasms
A CASE REPORT OF OHVIRA SYNDROME – A RARE CONGENITAL ANOMALY
Authors: Keerthi Kotha Sai , Shetty Nireeksha
Published: August 2023

Obstructed hemivagina with ipsilateral renal agenesis (OHVIRA) is a rare complex congenital structural abnormality of the female urogenital tract. The classical triad includes uterine didelphis, obstructed hemivagina and ipsilateral renal agenesis. It usually presents after menarche with non-specic and variable complaints of progressive pelvic pain, sometimes with regular menses causing a delay in the diagnosis. Mullerian duct anomalies (MDAs) are infrequently encountered in routine clinical settings, therefore making the diagnosis of OHVIRA even more challenging.[1] We report a case of a young adolescent female, referred to us for USG abdomen and pelvis, who presented with acute abdominal pain and acute urine retention to casualty. On USG, a provisional diagnosis of OHVIRA syndrome was given and MRI was suggested for conrmation and better delineation of the pelvis. The above diagnosis was conrmed on MRI, which is the gold standard imaging technique for assessing MDA
CEFTAZIDIME-AVIBACTAM ACTIVITY IN CARBAPENEM RESISTANT ENTEROBACTERALES (CRE) ISOLATES IN A TERTIARY CARE HOSPITAL IN WESTERN MAHARASHTRA: A RETROSPECTIVE OBSERVATIONAL STUDY
Authors: PA Sushmitha , Giri Suraj , Rai Preeti , Bala Anand Kavita , Pratap Singh Sanjay
Published: August 2023

Introduction: Increasing Carbapenem resistance is a global threat. Carbapenem resistance in Indian settings are predominantly mediated via the β
lactamases, NDM and OXA 48. The newly approved drug Ceftazidime-avibactam has potent activity against Carbapenem Resistant
Enterobacterales (CRE). However a limited literature on Ceftazidime-avibactam activity on CRE. Hence, the aim of this study is to highlight the
Ceftazidime-avibactam activity in CRE isolates. Material and Methods: We performed a retrospective observational study among 50 CRE and
conducted disc diffusion with Ceftazidime- avibactam to determine the susceptibility to the same. Results: There were 46 Enterobacteriaceae that
were detected to have carbapenemase producing genes. Out of 46, 14 (30.4%) isolates showed susceptibility to Ceftazidime-Avibactam by Disc
diffusion method; of which two were pure NDM producers and 7 were NDM co-producers and 5 were non NDM producers. Among 14 isolates
which were sensitive to Ceftazidime-Avibactam, the distribution of the isolates were E. coli (n=6, 43%) followed by K. pneumoniae (n=5, 36%)
and Proteus sps (n=3, 21%) Conclusion: In our study, Ceftazidime-avibactam demonstrated excellent in vitro activity against OXA-48 like
producing CRE (E. coli, K. pneumoniae) and a little activity was noted against pure NDM producers. Hence the use of the Ceftazidime-avibactam
based on antimicrobial susceptibility will be helpful in managing infections with multi drug resistant Gram negative organisms
“A COMPARATIVE CLINICAL STUDY OF PROSEAL LARYNGEAL MASK AIRWAY VERSUS AMBU AURA GAIN FOR INSERTION PARAMETERS AND AIRWAY DYNAMICS IN LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS. ”
Authors: Faiz Dawood , Agarwal Salony , Rastogi Bhawana , Tyagi Vasundhera , Kumar Sumit , Mondal Shristi
Published: August 2023

Background: Supraglottic airway devices are now routinely used in patient posted for surgery under general anaesthesia for obvious reason of stable hemodynamics and better outcome. The ProSealTM laryngeal mask airway has a modied cuff to improve the seal and a drain tube whereas Ambu® AuraGainTM (Ambu, Ballerup, Denmark), a relatively novel supraglottic airway device is integrated with gastric access and intubation capability. 66 patients posted for surgeries under general anaesthesia were Material and methods: enrolled for the study after clearance from institutional ethical committee. Patients of group A: received Proseal and group B received Ambu aura gain(AAU). Anesthesia technique was standardized. Ease of insertion, Number of attempt, Insertion time, Oropharyngeal seal pressure, Initial peak airway pressure, Peak airway pressure after insufations, Pharyngolaryngeal adverse events and Hemodynamic parameters were recorded. Demographic prole in Results: both the groups was comparable. The ease of device insertion was more smooth in PLMA than AAU group (p=0.042). The mean time taken for insertion of AAU was longer than PLMA p=0.007. mean oropharyngeal seal pressure was signicantly more in AAU than PLMA group. Whereas no of attempts, initial peak airway pressure (cm H2O), peak airway pressure after insufations (cm H2O), complications and hemodynamics were comparable in both the groups. Present study recommends that both Ambu Aura Gain and Conclusion: Proseal LMA can be effectively used in elective laparoscopic cholecystectomies under general anaesthesia.
STUDY OF IMPACT OF SITOPALADI CHURNA OVER BLOOD GLUCOSE LEVEL OF DIABETIC PATIENT- A SINGLE CASE REPORT
Authors: R Sonani Snehal , Kangad Rushikesh , Kullolli Vivekanand
Published: August 2023

Diabetes currently affects more than 62 million Indians, which is more than 7.2% of the adult population. The average age on onset is 42.5 years.
According to life style of today's era these age group is also simultaneously affected by bony problems, which will leads sedentary life and
ultimately increase rate of diabetes due to lack of exercise. This cycle continues in most of population of these age groups. There are so many
dietary restrictions for diabetic patient, especially sugar contained foods. These restrictions are not only limited for dietary food but also applied for
medicines. Because increased blood sugar level affects normal cellular functions as well as hampers normal nutrition to body cells. According to
Acharya Charak, Sitopaladi Churna is indicated for respiratory problems i.e., coughing, breathlessness, patient with excessive Kapha etc in that
context no contraindications mentioned specically for the Diabetic patients. But as per modern concepts Sitopaladi Churna can't be used in
Diabetic patients having such respiratory problems due to presence of 'Sita (Mishri-Sugar crystal)' in this polyherbal formulation. Polyherbal
therapy is an invention of Ayurveda which was introduced by 'Acharya Sharangdhara' for very efcient effect along with no complications. Such
combinations were made in such a way that one herbal drug will support to other herbal drug by aggravating its effect of reducing its side effects. Same phenomena are found in “Sitopaladi Churna”, Although having Sugar crystals in formulation, will not elevate the blood glucose level by compensatory effect of other herbal drugs in formulations. In this case report, effort has been made to evaluate the effect of Sitopaladi Churna over the blood sugar level which is the highly indicative assessment criteria for diabetes along with co-assessment of other symptomatology. This case report includes 64-year male patient who was treated with Sitopaladi Churna for complaint of coughing since last 15 days, and assessment of all over effect of Ayurvedic management
ROLE OF RENAL NEPHROMETRY SCORE IN PREDICTING PERI-OPERATIVE OUTCOMES FOLLOWING PARTIAL NEPHRECTOMY.
Authors: Ishaque Shaikh Hussain , Polara Amit , Vijayanand Potdar Ojas
Published: August 2023

Introduction: Renal cell carcinoma is 13th most common malignancy in the world.1 The prevalence of disease is more common in western countries compared to Asian countries, with prevalence of disease ranging between 1.1 and 6 per 100000 in Asian population.2 RCC is more common in males than in females.3 Aim: To study usefulness of RENAL nephrometry score in predicting peri-operative outcomes in patients with renal masses undergoing partial nephrectomy. Materials and Methods: A prospective single centre observational study was carried out at a tertiary care centre in western suburbs of India for a period of 18 months where all patients of renal masses satisfying inclusion and exclusion criteria undergoing Nephron sparing surgery were enrolled into study and data was collected and analysed. Results: In our study, renal masses with RENALNephrometry Score above 9 had greater tendency for open surgical approach, greater warm ischemia time and total operative time, greater blood loss and longer hospital stay with increased post-operative complications. Conclusions: Our study demonstrated that RENAL Nephrometry score is a useful tool in predicting surgical approach, warm ischemia time, total operative time, estimated blood loss, length of hospital stays, progression to total nephrectomy and post-operative complications.
EVANS SYNDROME: A CASE REPORT AND REVIEW
Authors: Muley Arti , Mitra Sona , Viramgam Kuldeep , Patel Zinal , Vishwa Trivedi
Published: August 2023

Evans Syndrome (ES) is dened as the concomitant or sequential association of warm Autoimmune Hemolytic Anemia (AIHA) with Immune Thrombocytopenic Purpura (ITP), and less frequently autoimmune neutropenia. Its chronic course is characterized by recurrent relapses and remissions. The typical clinical course is chronic and relapsing, and therapy is generally progressive and of poor outcome. We present a case of evans syndrome who was doing well on treatment with azathioprine and steroids but deteriorated and succumbed to her illness due to non compliance
COLD TYPE AUTOIMMUNE HEMOLYTIC ANEMIA - A CASE REPORT
Authors: Shiva Raju K. , Rizwan Mohammad , Manasa Alluri , Abdul Raheem Najiha
Published: August 2023

Autoimmune hemolytic anemia (AIHA) is a rare acquired immune disorder caused by autoantibodies that react with autologous red blood cells at
temperatures ≥ 37° C (warm antibody hemolytic anemia) or < 37°C (cold agglutinin disease) which leads to accelerated destruction of the red blood
cells. The etiology of the disease is not known. Yet, there are certain risk factors such as systemic lupus erythematosus (SLE), Rheumatoid arthritis,
and other such autoimmune conditions that aggravate the occurrence of AIHA. General symptoms associated with the disease include shortness of
breath, pale skin, generalized weakness, nausea, and vomiting. The conrmatory test to diagnose the type of AIHA is the Coombs test. A direct
antiglobulin test detects the presence of RBC-bound autoantibodies, and an indirect antiglobulin test indicates the presence of autoantibodies in the
serum. The standard treatment guidelines to treat AIHA include corticosteroids, blood transfusions in severe anemic cases, immunosuppressants
and iron supplements if needed.
IS THERE ANY DIFFERENCE OF RISK PREDICTION OF MYOCARDIAL INFARCTION AND STROKE AMONG ADULTS OF RURALAND URBAN POPULATION? A CROSS SECTIONAL STUDY
Authors: L Iti Jannatbi , Mudaraddi Roshan
Published: August 2023

Introduction: Cardio vascular disease is one of the major leading causes of death in both developed and developing countries affecting the
productive age group. There is a need to evaluate the risk prediction of major cardiovascular events in adult population of rural and urban areas.
Objectives: 1. To predict the ten year risk of major cardiovascular events using WHO/ISH risk assessment chart among adults aged 40 to 70 years
of urban and rural areas of Gadag. 2. To determine the association between risk prediction of major cardiovascular events and socio-demographic
factors among adults aged 40 to 70 years of urban and rural areas of Gadag. Methodology:Acommunity based cross sectional study was conducted
among adults aged 40 to 70 years among 200 adults, 100 from rural and 100 from urban areas. The study subjects were interviewed using
predesigned and pretested questionnaire containing information on socio – demographic prole, WHO/ISH risk assessment chart and Blood
pressure. Results:In the study the risk prediction of myocardial infarction and stroke was less than 10% among majority of study participants (rural
= 79%, urban = 84%). Conclusion:risk predication was more in rural population compared to urban population and increases with age.
BIRTH SPACING-NEED OF THE HOUR: A CROSS SECTIONAL STUDY ON UTILIZATION PATTERN OF TEMPORARY CONTRACEPTION AND ITS CORRELATES AMONG WOMEN IN CENTRAL KERALA
Authors: Mohan Aiswarya
Published: August 2023

Pregnancy-related complications are responsible for a large number of
deaths amongst mothers and infants, predominantly in developing
countries. [1] The current focus of the international community is to
reduce the global maternal mortality ratio to less than 70 per 100,000
live births by 2030 as per the third Sustainable Development Goal [2]
Estimation of daily global solar radiation based on different whitening applications using temperature in Mediterranean type greenhouses
Authors: Karaca Cihan
Published: August 2023

The study aimed to estimate the daily global solar radiation (Rs) in Mediterranean-type greenhouses. Five different temperature-based Rs estimation models developed for open-field conditions were calibrated and validated in Mediterranean-type greenhouses in Almeria, Spain and Antalya, Türkiye, between August 26, 2013, and January 1, 2023, and between October 1, 2018, and 1 January 2023, respectively. Whitening applications were categorized according to greenhouse light transmissivity and classified as follows: without whitening or light-whitening, medium-whitening, and severe-whitening. Additionally, the best-performing model were compared with greenhouse plastic light transmissivity method. The estimation performance of the models was evaluated using the statistical indicators of the p-value of the slope, determination coefficient (R2), Nash–Sutcliffe model efficiency coefficient (NSE), root mean square error (RMSE), mean absolute error (MAE), relative error (RE), and Willmott Index (d). Compared with the other models, the Bristow and Campbell model showed a slightly higher performance in all whitening applications. Although the light transmissivity coefficient method performed slightly better than the temperature-based Rs estimation model, there was no statistical difference in the performances of the estimation models. Temperature-based estimation models offer a highly viable alternative for individuals who rely on the light transmittance approach to estimate Rs in greenhouses. This method can prove particularly useful in areas where measuring Rs outside the greenhouse is not possible or where partial time measurements cannot be taken owing to equipment malfunctions. All calibrated models can be used to estimate solar radiation using temperature data from various Mediterranean countries with similar climates and greenhouse cultivation.
Understanding trends and gaps in global research of crop evapotranspiration: a bibliometric and thematic review
Authors: Barrera WilfredoB.  Jr. , Ferrise Roberto , Dalla Marta Anna
Published: August 2023

Estimating crop evapotranspiration (ETc) is crucial for ensuring sustainable and efficient agricultural water management. Although this subject has garnered significant attention from the global scientific community, a comprehensive study encompassing the diversity, trends, and dynamics of research themes is currently lacking. To address this knowledge gap, this review employed a combined bibliometric and thematic approach to analyze bibliographic data from 1872 documents retrieved from the Web of Science™ core collection, spanning the period 1987–2022. The main findings of this review are as follows: (1) the scientific landscape is predominantly shaped by institutions from the USA and China; (2) the journal Agricultural Water Management emerged as the most prolific, with the highest number of publications and total citations; (3) a broad range of topics within ETc research were identified, with a notable emphasis on remote sensing-related subjects; (4) strategic coordination mapping revealed that ETc and reference evapotranspiration (ETo) remains an underdeveloped area of study; (5) climate change and machine learning emerged as key topics of significant scientific concern. The results suggest a need for enhanced institutional collaborations and expanded research investigations, particularly in regions grappling with agricultural water scarcity. Furthermore, research investigations should focus on ETc and ETo to fill existing knowledge gaps and advance both theoretical understanding and practical applications. Future studies should aim to contribute to the understanding of the impacts of climate change on ETc by leveraging machine learning techniques and enhancing our understanding of crop water requirements and their application in irrigation management, while also ensuring continuous updates to the existing body of knowledge to meet future challenges.
nowledge, Attitudes and Perceptions of COVID-19 among Chronic Hemodialysis Patients in the Nephrology Department of the Amirou Boubacar Diallo National Hospital (HNABD) in Niamey
Authors: Tondi Zeinabou Maiga Moussa , Garba Abdouramane , Bonkano Djibrilla , AbdelAziz Nassima Hissein , Manirazika Jean Claude , Diongole Hassane Moussa , Rosine Toffa Appolinaire , Illiassou ABOUBACAR , Abdou IDE
Published: August 2023

Introduction: Chronic haemodialysis patients and kidney transplant patients are vulnerable patients with a high risk to develop severe complications of Covid-19 [2]. The objective of our study is to determine the knowledge, attitudes the perception of COVID-19 and vaccination of chronic hemodialysis patients in the nephrology department of the Amirou Boubacar Diallo national hospital in Niamey. Method: This is a study on the knowledge, attitudes and perceptions of COVID-19 of chronic haemodialysis patients in the nephrology department of the Hôpital National Amirou Boubacar Diallo (HNABD) in Niamey. Results: Our study included 200 chronic hemodialysis patients. The average age was 46.44 +/- 13 years, with extremes ranging from 18 to 80 years. Almost all patients (98%) had heard of COVID-19. However, 9.50% did not believe in the existence of COVID-19, and only 5% had witnessed cases of people with the disease. More than the majority of patients were aware of the clinical manifestations of COVID-19, the modes of transmission, and barrier measures. A third of patients (32%) claimed that there was a treatment for this pandemic. Only a small number (2.5%) of patients were confined. 38% of patients said that the dialysis room would be a risk factor for contamination. And 41% of patients were in favor of vaccination. Conclusion: The existence of COVID-19 is no longer in doubt, and Nigerien haemodialysis patients have a good level of knowledge about covid-19. Awareness-raising about barrier measures, disease surveillance methods and, above all, vaccination should be increased.
Coenzyme Q 10 in Infertile Men with Idiopathic Asthenozoospermia: A Single Blind Placebo-Controlled, Randomized Trial
Authors: Debnath Mitu , Deeba Farzana , Ishrat Shakeela , Satu Farhana Karim , Chowdhury Fahmida , Ara Kazi Shamim , Nazneen Sohely
Published: August 2023

Background: Many studies have focused on male infertility. There is limited evidence about the influence of nutrition on quality of semen. Accumulating evidence suggests that oxidative stress plays an important role in the development of male infertility and recently antioxidants have been tried to treat men with idiopathic infertility. Objective: To evaluate the effectiveness of coenzyme Q-10 treatment in improving sperm motility in men with idiopathic asthenozoospermia. Methods: This randomized controlled study conducted in the Department of Reproductive Endocrinology and Infertility, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from January 2021 to December 2021. Total 74 diagnosed cases of idiopathic asthenozoospermia were selected for medication was included in this study. Eligible man who gave their informed consent was allocated into either Group A (Coenzyme Q-10) or Group B (Placebo) on the basis of computer generated table. Group A received coenzyme Q-10 100 mg two times daily and Group B received placebo for same doses for 12 weeks. Then pretreatment and post treatment semen parameters, including sperm concentration, total motility, progressive motility and morphology was assessed. Results: Post treatment motility (37.8±11.1 vs 26.3±8.8%), progressive motility (30.0±7.9 vs 22.4±7.7) and total motile sperm count (33.5±24.4 vs 21.4±14.3 million) were significantly higher in coenzyme Q-10 group than placebo group (p<0.05). In coenzyme Q-10 group, motility (37.8±11.1 vs 25.2±8.1%), progressive motility (30.0±7.9 vs 22.5±7.0) and total motile sperm count (33.5±24.4 vs 20.0±13.6 million) were significantly increased in post treatment than pretreatment patients (p<0.05), but not found in placebo group. Improvement of sperm motility was significantly higher in coenzyme Q-10 group than placebo group (60.0% vs 5.6%). Conclusion: In conclusion, coenzyme Q10 administration, total motility, progressive motility and total motile sperm count were .....