bluuebunny/crossref_metadata_2025 huggingface dataset:
Apakah Emotional Intelligence dipengaruhi gender?: Analisis perbedaan kecerdasan emosi kaitannya dengan manajemen konflik suami-isteri dalam masa kritis perkawinan
Authors: Hidayah Bidayatul , Ariyanto Amarina Ashar , Hariyadi Sugeng
Published: April 2022

Abstrak

Kecerdasan emosi/emotional intelligence menjadi menarik dibahas karena selalu bersangktan dengan aspek kehidupan seperti membina hubungan sampai dengan penyelesaian konflik. Studi gender konvensional menyebutkan terdapat perbedaan antara laki-laki dan perempuan terutama dalam emosi keduanya. Hal ini dikaitkan dengan perbedaan jenis kelamin secara fisiologis dan peran gender secara sosial. Studi ini bertujuan untuk mengetahui perbedaan emotional intelligence laki-laki dan perempuan dalam konteks usia kritis perkawinan dimana konflik perkawinan seringkali terjadi. Sebanyak 91 pasangan suami istri (N=182) berpartisipasi dalam studi ini untuk mengetahui emotional intelligence yang dimiliki dan kaitan emotional intelligence terhadap manajemen konflik perkawinan. Temuan mengenai hasil korelasi dan komparasi serta pembahasan akan dibahas lebih lanjut dalam diskusi.
Pengelolaan Stres dan Peningkatan Produktivitas Kerja selama Work From Home pada Masa Pandemi COVID-19
Authors: Shabuur Muhammad Ishak , Mangundjaya Wustari L.
Published: April 2022

Ketika pandemi COVID-19 menyebar secara global, pedoman kesehatan masyarakat menyarankan semua karyawan untuk bekerja dari rumah (WFH). Di Indonesia, belum banyak perusahaan yang menerapkan WFH sebelumnya dikarenakan praktik manajemen yang masih tradisional, tentu penyesuaian terhadap WFH merupakan pengalaman baru untuk sebagian besar karyawan. Sementara itu, sebagian besar penelitian yang diulas mengenai dampak karantina melaporkan efek psikologis negatif pada individu termasuk gejala stres, kebingungan, dan kemarahan. Berdasarkan situasi tersebut, penelitian ini bertujuan untuk melihat kembali pengaruh sikap fleksibilitas kerja terhadap WFH melalui flexibility working options terhadap produktivitas kerja selama masa karantina Pandemik COVID-19 dan menguji strategi coping stress sebagai moderator pada hubungan antara kedua variabel tersebut. Penelitian ini melibatkan 421 karyawan yang bekerja secara WFH pada sektor swasta, publik dan pemerintah di Indonesia. Responden dikumpulkan dengan menggunakan teknik convenience sampling melalui penyebaran kuesioner secara online. Pengujian efek moderasi dilakukan dengan menggunakan teknik moderated regression analysis (MRA). Hasil penelitian menunjukkan bahwa strategi koping memoderasi hubungan secara positif, sehingga hubungan antara fleksibilitas kerja dan produktivitas kerja semakin meningkat ketika karyawan menerapkan mekanisme koping yang berfokus pada masalah untuk mengendalikan stresor dan menjaga produktivitas kerja mereka selama pandemi COVID-19.

When the COVID-19 pandemic spread globally, public health guidelines recommend all workers to work from home (WFH). In Indonesia, not many companies have implemented WFH before because of traditional management practices, of course adjusting to WFH is a new experience for most workers. Meanwhile, most of the studies reviewed regarding the effects of quarantine reported negative psychological effects including symptoms of stress, confusion, and anger. Based on this situation, this study aims to review the influence of work flexibility attitudes towards WFH through flexibility working options on work productivity during the COVID-19 Pandemic quarantine period and test the coping strategy as a moderator on the relationship between the two variables. This study involved 421 working from home employees in the private sector, public sectors and government in Indonesia. Participants were taken using convenience sampling techniques through the distribution of questionnaires online.  Testing for moderation effects is done by using moderated regression analysis (MRA) technique.  The results show that coping strategy positively moderates the relationship, such that the relationship between flexibility working options and work productivity is increasing when employee implement coping mechanisms that focus on problems for control stressors and maintain their work productivity during the COVID-19 pandemic.
Evaluasi Kerjasama dalam Pengembangan Perpustakaan Universitas Riau dengan Perpustakaan Arsip dan Dokumentasi Provinsi Riau
Authors: Yulia Fera , . Rismayeti , Amelia Vita
Published: April 2022

This research is entitled "Evaluation of Cooperation in the Development of the Riau University Library with the Archives and Documentation Library of Riau Province". The purpose of this research is to find out the form of realization of cooperation and what are the obstacles faced by the Riau University Library with the Riau Province Archives and Documentation Library in the development of the Riau University library. The method used in this research is qualitative method. Data collection techniques using interviews. With the number of informants as many as 10 people. The results of data analysis show that the form of realization of collaboration with the Riau University library is collaborating with the Archives and Documentation Library of Riau Province, namely. Becoming a Member of the Suman HS Regional Library With the Electronic system, the collaboration has not been implemented. The obstacles faced by the Riau University Library and the Riau Province Documentation Archives Library are the change in the head of the library, lack of coordination between leaders, the application is not integrated, and the lack of experts on duty.
Analisis Tindak Tutur Wabi Hyougen ???? (Meminta Maaf) dalam Drama Tennou No Ryouriban (??????) Suatu Tinjauan Pragmatik
Authors: Saputra Adnan , . Kasmawati , . Taqdir
Published: April 2022

Penelitian ini bertujuan untuk menjelaskan variasi-variasi tindak tutur meminta maaf apa saja yang terdapat dalam drama Tennou no Ryouriban (??????) dan faktor-faktor apa saja yang memengaruhi seorang penutur dalam memilih variasi tersebut. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan memanfaatkan data-data tuturan yang diperoleh dalam drama yang dikaji. Data yang diperoleh kemudian diklasifikasi berdasarkan variasinya lalu dianalisis faktor-faktor apa saja yang memengaruhi pemilihan variasi tuturan-tuturan tersebut.Dari hasil penelitian, ditemukan tiga ragam tuturan meminta maaf dalam drama Tennou no Ryouriban yaitu sumimasen, gomennasai dan moushiwake arimasen dengan jumlah 18 data tuturan. Sementara itu, ditemukan empat faktor-faktor yang paling memengaruhi seorang penutur dalam memilih tuturan-tuturan tersebut yaitu ningen kankei atau hubungan antar manusia, tachiba–yakuwari atau posisi dan peranan, ba a tau latar belakang, serta katachi atau wujud penyampaian
Kehidupan Sosial Budaya dan Sosial Ekonomi Masyarakat Tegalalang-Gianyar di Masa Pandemi
Authors: Inten Asmariati Anak Agung
Published: April 2022

Penelitian ini bertujuan untuk mengetahui Kehidupan sosial budaya dan sosial ekonomi masyarakat desa Tegalalang di masa pandemi dan juga untuk mengetahui tantangan dalam menghadapi situasi pandemi terutama bagi kehidupan sosial budaya dan ekonomi masyarakat desa, yang sebagian besar penduduk generasi muda, perekonomiannya telah beralih kesektor pariwisata. Penelitian ini merupakan penelitian kualitatif yang bersifat deskriptif. Hasil dari penelitian ini menyoroti kehidupan sosial budaya masyarakat desa yang sangat kental akan tradisi dan adat istiadat. Tradisi ngerebeg merupakan tradisi yang ada di Tegalalang dan hingga sekarang ini tradisi ini tetap dilaksanakan. Pelaksanaan ngerebeg bertepatan dengan piodalan di Pura Duur Bingin. Di masa pandemi masyarakat desa Tegalalang tradisi ngerebeg tetap dilaksanakan dengan mengikuti protocol kesehatan sesuai dengan anjuran pemerintah. Disektor ekonomi masyarakat desa Tegalalang terutama  generasi muda banyak yang bekerja di sektor pariwisata. Adanya pandemi saat ini, berdampak pada aktivitas di sektor pariwisata dibatasi oleh pemerintah ditandai oleh ditutupnya penerbangan internasional sementara waktu. Hal ini berdampak pada tidak ada kunjungan wisatawan mancanegara ke Indonesia khususnya ke Bali. Banyak tenaga kerja yang dirumahkan begitu pula dengan tenaga kerja yang ada di Tegalalang. Mengatasi hal tersebut banyak kemudian yang beralih ke sektor usaha dengan bergerak pada usaha UMKM. Ada pula yang kemudian kembali ke sektor pertanian dan perkebunan seperti adanya budi daya papaya dan budi daya kopi. Apalagi sekarang banyak dibukanya café khusus kopi. Kondisi ini menjadi tantangan bagi generasi muda juga bagi masyarakat desa Tegalalang dalam menghadapi situasi pandemi ini. Kehidupan terus berlangsung dan kebutuhan masyarakat juga akan terus bertambah sehingga untuk mengatasi situasi pandemi ini membuat masyarakat desa segera adaptif dan kreatif dalam mengatasi perekonomian keluarga, maka dengan memulai usaha diharapkan mampu memenuhi kebutuhan ekonomi mereka.
Harmonisasi Hubungan Etnis Tionghoa dan Etnis Bali di Kintamani: Kajian Kritris Terhadap Multikultur dalam Masyarakat Bali
Authors: Setiawan I Ketut
Published: April 2022

One of the ethnic groups in Bali, apart from the Balinese ethnicity, is the Chinese. From arhaeological evidende, it can be seen that since the seventh century, Chinese ethnicity  has existed in Bali. The ethnic Chinese who live in harmony with the Balinese are interesting to be studied, because outside Bali, this ethnic relationship shows a tendency to be disharmonious and conflicts often lead to violence. The exixtence of Chinese ethnic in Kintamani is interesting to be studied because the two ethnic group in. Kintamani knit a harmonious relationship, so as to create a harmonious life. The purpose of this study is to deconstruct social phenomena so that they can understand the various reasons that cause the two ethnic groups to live side by side in harmony. This study uses a qualitative descripte method with a critical ethnographic approach in the perspective of cultural science. Data were collected by observation, interviews, and document studies. The data were analyzed qualitatively by using  critical social theory. The results of the study indicate that the harmonious relationship between ethnicities occurs because there is power and capital played by both ethnicities, in addition to historical and cultural factors.
A Corpus Based Analysis of Adjectives Adorable, Charming, and Cute in Corpus Contemporary American English (COCA)
Authors: Ramayanti Ni Putu Desi , Sukarini Ni Wayan , Weddha Savitri Putu
Published: April 2022

In order to avoid misunderstanding in the process of communication, knowing well the meaning of a word is important. Especially, when the two or three words share similar meaning and often used interchangeably in the sentences such as the adjectives word; adorable, charming, and cute. Therefore, this study aimed to find and to analyse the collocative meaning of the three adjectives. In this study, the data were collected from Corpus of Contemporary American English (COCA) by applying the documentation method with the note-taking technique. This study used a corpus-based analysis, with the help of the theory of collocative meaning and supported theory of lexical collocation were applied. The result showed that the collocative meaning of the three adjectives share similar meanings which collocated with the word attractive. Moreover, the three adjectives were most likely to co-occur with nouns such as; baby, guy, boys, and etc. The three adjectives were also commonly paired up with adverbs such as; quite, so, always and etc.
Pênfigo Dermatofítico - Relato de Caso
Authors: Costa Karolina Fernanda de Souza , Carvalho Flávia Clare Goulart de
Published: April 2022

Introdução: O Pênfigo dermatofítico é uma doença cutânea extremamente rara, com baixas casuísticas no Brasil, essa enfermidade apresenta-se da mesma forma que o pênfigo superficial, acometendo a barreira mucocutânea de cães e gatos. Objetivo: relatar um caso de pênfigo dermatofítico em um canino, fêmea, SRD, de 4 anos, de 26 Kg, o qual foi atendido no Hospital Veterinário Escola do UNIFAA. Relato de caso: O animal apresentava inicialmente alopecia, eritema, erosão, crostas melicéricas, descamação e colarinho epidérmico. Foi realizada uma cultura fúngica e uma biópsia, onde foi possível observar a presença do fungo Trichophyton spp. No exame histopatológico o resultado compatível com pênfigo foliáceo, com isso  foi possível diagnosticar que o animal apresentava um quadro incomum de dermatofitose e pênfigo ocorrendo de forma simultânea, não sabendo exatamente qual enfermidade causou a outra. Foi instituído o tratamento com mupriocina tópica e diprogenta® creme nas lesões, deflazacort na dose de 0,15 mg/Kg SID até a remissão das lesões no tratamento reativo, no tratamento pró-ativo duas vezes por semana e depois substituindo por azatioprina 2,0 mg/kg SID 30 dias, depois reduzindo para 1,0 mg/kg SID e ração light. Resultados: O animal apresentou melhora total, sem apresentar novamente os sinais clínicos e com o exame de cultura fúngica negativa, porém na ausência do imunossupressor as lesões alopecias ulcero-crostosas retornavam concluindo diagnóstico de pênfigo superficial. Conclusão: Por ser uma doença crônica e autoimune, o paciente precisara realizar o controle dela pelo resto de sua vida, com o uso de medicação diária a base de imunossupressores.
Lipidose Hepática Felina - Relato de Caso
Authors: Gomes Júlia Silva , Azevedo Sylvia , Braz Maria Luiza
Published: April 2022

Introdução: A lipidose hepática felina (LHF) é uma das doenças mais frequentemente diagnosticadas na espécie felina, sem predisposição por sexo, idade ou raça. Objetivo: Sendo assim o presente relato teve como objetivo demonstrar a importância do reconhecimento dos sinais e da intervenção em gatos com lipidose hepática, devido ao potencial risco de óbito caso o manejo correto não seja realizado. Relato do caso- Foi atendida em uma clínica veterinária, uma gata, SRD e de três anos. De acordo com o tutor o animal estava a quatro dias inapetente, frequentes episódios de vômito e havia perdido cerca de dois quilos. Segundo o tutor o quadro começou após a família ter mudado de residência. No exame físico o animal apresentava-se apática, magra, com o pelame arrepiado e sem brilho, orelhas e mucosas ictéricas. Após a realização dos exames complementares foi constatado que o animal estava com um quadro de lipidose hepática felina. O animal foi internado para o adequado tratamento e a colocação de sonda nasogástrica para restituir a alimentação. Após a estabilização do quadro foi recomendado a colocação de sonda esofágica e em seguida foi dada alta ao paciente com continuidade do tratamento de forma domiciliar. O animal demonstrou-se responsivo durante o tratamento. Conclusão: Sendo assim, através do relato de caso, conclui-se que a lipidose hepática felina é uma doença relevante na clínica de felinos, devido à alta recorrência e potencial risco de óbito. Os pilares para um bom prognóstico relacionam um correto diagnóstico e a instituição de um tratamento precoce, em conciliação com o realizado no presente relato.
FSBU 26/2020 – Capital Investments, and FSBU 6/2020 – Property, Plant and Equipment: The issues of application
Authors: LISOVSKAYA Irina A. , TRAPEZNIKOVA Natal'ya G.
Published: April 2022

Subject. This article considers certain aspects of accounting for fixed assets, the implementation of which may cause certain difficulties in accounting.
Objectives. The article aims to identify and analyze the ambiguous provisions of Federal Accounting Standards FSBU 6/2020 and FSBU 26/2020, which may cause practical difficulties at the stage of transition to the application of these standards, and find possible ways to solve the problems.
Methods. For the study, we used a systems analysis and generalization of legislative and regulatory documents, and research literature on the study subject.
Results. The article highlights the controversial issues in the field of fixed assets accounting caused by the conciseness or absence of separate regulations of FSBU 6/2020 and FSBU 26/2020, highlights the aspects of accounting that require the use of professional judgment, and formulates provisions that should be enshrined in internal accounting standards.
Conclusions and Relevance. Effective development of new methodological approaches to the recognition and subsequent reflection of capital investments and fixed assets will require expanding the scope of use of professional judgment. To solve this problem, it is necessary to improve the competencies of domestic specialists in the field of IFRS and expand the experience of applying professional judgment. The results of the study can be used in scientific and practical activities, training specialists in the field of accounting, and for the development of proposals for improving the Russian accounting methodology, focused on convergence with modern international practice.
The first attempt to uniform accounting in the USA: Individual and consolidated financial statements
Authors: KOLCHUGIN Sergei V.
Published: April 2022

Subject. This article examines the first attempts to unify accounting in the United States and analyzes the information needs of users of accounting information, which led to the emergence of consolidated financial statements.
Objectives. The article aims to study the theoretical and methodological foundations of unification of US accounting in the context of individual and consolidated financial statements, as well as identify the theoretical and methodological foundations of consolidated financial statements as an independent type of financial reporting.
Methods. For the study, I used combinations of analysis and synthesis, induction and deduction, and historical and logical research methods.
Results. The article shows that the unification of accounting in the United States took place through the adoption of uniform rules, not through the recognition of generally accepted accounting principles. The first unified accounting rules were focused on meeting the information needs of banks and banking organizations as the main source of investment of commercial companies. Despite the existence of theoretical developments in the field of consolidated financial statements and the preparation of the first consolidated balance sheets in practice, preference was given to individual financial statements, which was due to the need to assess the creditworthiness of a potential borrower applying for bank financing.
Relevance. The results obtained can be used in the development of the theory and methodology of consolidated accounting as an independent type of accounting of a group of companies.
A critical review of the Russian economy
Authors: SMIRNOV Valerii V.
Published: April 2022

Subject. This article explores the structural capabilities of the Russian economy.
Objectives. The article aims to determine the priorities for the development of the Russian economy.
Methods. For the study, I used the methods of statistical, neural network, and cluster analyses.
Results. The article justifies the need to pay primary attention to such parameters of economic development as GDP per capita, gross debt and incomes of the general government sector, and changes in the volume of imports.
Conclusions. The results of the study can be used by the authorities to develop programmes for the advancement of economic sectors to overcome the structural crisis.
Clustering of hydrogen infrastructure in the Republic of South Africa: Institutional prerequisites and cooperation with the Russian Federation
Authors: SALYGIN Valerii I. , DENIZ Dar’ya S.
Published: April 2022

Subject. The article addresses indicative plans for hydrogen energy development in South Africa, investigates economic linkages strengthening between South Africa and Russia. Objectives. We focus on analyzing the innovative segment of energy industry in South Africa, defining priority areas of cooperation for Russian enterprises. Methods. The study employs tools and techniques of system analysis. Results. The paper provides a detailed analysis of the production of hydrogen fuel cells in South Africa, with prospects for creation of vertically integrated enterprises. We present variants of cooperation between Russia and South Africa in the field of development and creation of innovative technological solutions. Conclusions. In South Africa, opportunities are being created for carbon-neutral fuel production based on hydrogen. By 2050, the country expects a radical transformation of its energy industry. The new system will rest on renewable power generation and hydrogen energy.
Deoffshorization as an important direction of economic policy
Authors: TRIGUB Ekaterina Yu.
Published: April 2022

Subject. The article considers the system of economic relations associated with the functioning of offshore jurisdictions.
Objectives. The focus is on the analysis of current trends in deoffshorization, development of an up-to-date definition of the ‘deoffshorization’ term.
Methods. The study employs methods of logical and statistical analysis.
Results. The paper determines the level of dependence of the Russian economy on offshore companies. It establishes that most of foreign direct investments come to Russia from offshore and sparring-offshore jurisdictions.
Conclusions. To create a favorable investment climate, measures to deoffshorize the Russian economy are required.
Development of international trade of the European Union and mechanisms of partner countries’ interaction in the domestic market
Authors: MALAKHOVA Tat'yana S.
Published: April 2022

Subject. The article considers international trade in the European Union countries in the face of external challenges and threats. Objectives. The purpose is to assess the international trade of the European Union, analyze programs and mechanisms of interaction with partner countries in the internal market. Methods. The study draws on historical-logical and dialectical principles, and employs method of scientific abstraction. Results. I explored trends in the total exports of the European Union countries for 2019–2021, defined the share of the countries of this integration group in world exports and imports in 2016–2021, compiled a forecast of economic indicators for the near future. Conclusions. When implementing the Single Market Program, economic entities will seek sustainable growth, increase jobs, and this will lead to strengthening the position of partner countries in the internal market and beyond.
Disclosure of Corporate Social Responsibility on Corporate Financing Constraints with Financial Transparency Moderating Variables
Authors: Islah Jingga Novebreza
Published: April 2022

Abstrak

This study aims to determine the effect of corporate social responsibility on corporate financing constraints with financial transparency as a moderating variable. The sample used in the manufacturing sector companies listed on the Indonesia Stock Exchange for the 2015-2019 period as many as 89 companies were selected using a purposive sampling technique. This study uses panel data regression analysis and moderated regression analysis (MRA). The results of the study indicate that corporate social responsibility affects corporate financing constraints. Meanwhile, the variety of corporate social responsibility which is moderated by financial transparency affects corporate financing constraints. In addition, the control variable of company age also affects the corporate financing constraint, while the growth variable does not affect the corporate financing constraint.
Some features of planning preventive measures
Authors:   State Fire Academy of EMERCOM of Russia, SATIN A.P. , BURLACHENKO K.Gr. ,   State Fire Academy of EMERCOM of Russia, REPIN S.V. ,   Main Directorate of EMERCOM of Russia for Nizhny Novgorod Region
Published: April 2022

Purpose. The article describes the experience of the hierarchy analysis method to develop management decision making support systems to ensure fire safety prevention. The possibilities of using special computer programs as information decision making support subsystems with a library of models based on the analytical hierarchy method of planning working time of state fire supervision inspecting officers are studied. Methods. The existing models of management decision support systems built using the hierarchy analysis method developed by Th. Saaty have been analyzed. Hierarchical ideas about the actual performance in state supervision bodies in modern conditions have been developed. Findings. Layerings of some issues in implementing supervisory activities in protecting educational facilities, residential and industrial buildings have been developed. Separately layering the issue of planning small segments of working time for a state fire supervision inspecting officer is considered. Research application field. The results of the study can be used in working out effective technical solutions in state fire supervision of EMERCOM of Russia management. The constructed models can be used to optimize the inspector's workload and to support managerial decision-making by Chief State Inspecting Officer for Fire Supervision. The models allow considering a large number of criteria and alternatives, and determining their weights taking into account various situations. Conclusions. The possibilities of using special computer programs based on the analytical hierarchy method, considered in the article, will reduce experts' interviewing time. This optimizes workload when planning the working time of state fire supervision inspecting officers, which will increase the time for implementing preventive and other measures and improve their quality.
Level of physical activity, body mass index (BMI), and sleep patterns in junior and senior high school students of Kediri city and regency
Authors: Sugito  , Allsabah Muhammad Akbar Husein , Trio Kurniawan Bambang
Published: April 2022

During the current pandemic, the pattern of activity, lifestyle, and sleep quality of students at the school level has changed due to the Covid 19 outbreak which required students to reduce their activities outside the home. The purpose of this study was to find out the level of physical activity, body mass index (BMI), and sleep patterns Junior High School (SMP) and Senior High School (SMA) students of Kediri City and District. This study uses quantitative qualitatively described methods. The subjects of this study are 548 participants of the Junior High School (SMP) and Senior High School (SMA) in Kediri City and District. Instruments in this study for physical activity levels use IPAQ (International Physical Activity Quessionare) questionnaires, body mass indexes using BMI questionnaires, and sleep patterns using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. The results of this study show that physical activity levels of 81% fall into the Moderate category, Body Mass Index by 63% falls into the Normal category, and sleep patterns by 83% fall into the bad category. The results of this study have limitations on certain levels of education and a limited number of samples who perform new habits due to the Covid-19 pandemic. The results of this study show the real impact of the Covid-19 pandemic for school students, so in the future there needs to be a research study that can overcome the impact of the pandemic on students, namely regarding health and lifestyle.
Multi-electron Transfer by U(ɪɪ) and Masked U(ɪɪ) Complexes
Authors: Modder Dieuwertje K. , Mazzanti Marinella
Published: April 2022

Complexes of uranium in low oxidation state have shown the ability of activating non-reactive small molecules such as N2. However, the multi-electron transfer required for such activation, remains limited in uranium chemistry. Here, we review our recent research on the use of different strategies to overcome this issue, which has led to the isolation of a diuranium(ɪɪɪ) bridging oxide complex that reacts as a U(ɪɪ) synthon able to effect one-electron transfer per uranium center to N-heterocycles and multi-electron transfer to diphenylacetylene and azobenzene. We also showed that a closely related molecular U(ɪɪ) complex effects the same reactions providing the first unambiguous example of a monouranium four-electron transfer.
Alkali Metal Metal(ates) Containing Divalent Earth Abundant Transition Metals
Authors: Logallo Alessandra , Hevia Eva
Published: April 2022

Recent advances in cooperative chemistry have shown the enormous potential of main group heterobimetallic complexes for the functionalisation of aromatic molecules. Going beyond main group metal chemistry, here we provide an overview on the synthesis, structure and reactivity of bimetallic complexes which combine an alkali-metal (AM= Li, Na) with a divalent earth-abundant transition metal (M= Mn, Fe, Co, Ni), containing the utility silyl amide HMDS (HMDS = N(SiMe3)2). Advancing the understanding on how cooperative effects operate in these bimetallic (ate) systems, selected examples of their applications in deprotonative metalation are also discussed with special emphasis on the constitution of the metalated intermediates.
Gas impurity in calcination atmosphere governing electrochemical properties of LiNi0.8Mn0.1Co0.1O2 cathode material for lithium ion batteries
Authors: Kim Sanghoon , Wang Ronghui , de Verthamon Guillaume , Briand Francis , Prost Laurent
Published: April 2022

In this work, we investigated the influence of gas impurity in oxygen as calcination gas on the electrochemical properties of high Ni LiNi0.8Mn0.1Co0.1O2 (NMC811) cathode materials. Among investigated gas compositions, the oxygen mixed with a small amount of argon (96% O2, 4% Ar) shows the same level of Li/Ni cation mixing as 100% O2 sample, with not only a very stable discharge capacity retention (89% at 200 cycles) but also higher C-rate capability (67% at 20C) compared to other samples. Despite well suppressed Li/Ni cation mixing, 100% O2 sample suffers from an over-oxidation of Ni and Co of the surface, leading to an increase of surface resistance, as a consequence, a fast capacity fade over cycling with lower C-rate capability compared to the material calcined under 96% O2/4% Ar. This result demonstrates that calcination gas composition plays a key role in determining the electrochemical properties of high Ni cathode materials, not only in terms of Li/Ni cation mixing in the bulk structure, but also the oxidation properties of Ni, Co at the surface.
Photocaged Activity-Based Probes for Spatiotemporal Detection of Protein S-sulfenylation in Living Cells
Authors: Zhang Jiahao , Peng Haiyue , Chen Zi'an , Li Guorui , Huang Jing
Published: April 2022

Protein cysteine residues have unique reactivity due to the low redox potential of its thiol side chain. Protein S-sulfenylation (protein sulfenic acid), as one of the most significant oxidative post-translational modifications (OxiPTMs), plays a vital role in regulating protein function. Due to the transient presence of sulfenic acid in living cell, many detecting methods have been limited. Activity-based probes provide powerful tools to elucidate this process, so their discovery has been at the forefront of redox biology. In this study, two caged cysteine sulfenic acid probes DYn-2-ONB, DYn-2-Cou with either an o-nitrobenzyl or coumarin protecting group were developed. Both probes can be efficiently uncaged via irradiation to produce the active C-nucleophile probe DYn-2. Labeling assay in living cells demonstrated DYn-2-ONB exhibited better labeling capacity compared with DYn-2, providing it as a powerful tool to detect protein S-sulfenylation in spatio-temporally controllable manner.
Si-based Composite Anode for Li-ion Batteries with Enhanced Electrochemical Performance via CuCl2·2H2O Assisted Coating of PDA
Authors: Zhang Xingyu_Polyu , Li Ying , Zheng Tianye , Zhou Ruitao , Lam Kwok Ho
Published: April 2022

Silicon (Si) is a promising anode material for Li-ion batteries but its application is limited due to its low electronic conductivity and severe volume change during the lithiation/delithiation process. Recently, coating a carbon layer on the Si surface and doping the alloy phase into the bulk Si have been considered as effective approaches to resolve the aforementioned issues. The present study proposes a facile method via coating the polydopamine (PDA) with the assistance of CuCl2·2H2O followed by a high-temperature annealing process to successfully fabricate the Si-based anode material with a unique structure of Si-Cu3Si@C. Owing to the synergistic effect of carbonized PDA layer and doped Cu3Si phase, both structural stability and electronic conductivity of electrode have been significantly enhanced. The Si-Cu3Si@C composite anode not only exhibited a high initial reversible capacity of 1.44 mAh·cm-2 (2483 mAh·g-1) with an initial coulombic efficiency of 83.2%, but also demonstrated a good capacity retention of 91.3% after 100 cycles at the current density of 0.28 mA·cm-2 (480 mA·g-1). In particular, an excellent reversible capacity of 0.75 mAh·cm-2 (1339 mAh·g-1) after a long-term test of 400 cycles was displayed at the high current density of 1.4 mA·cm-2 (2500 mA·g-1).
Calibrate Ligand-ligand Interaction on Nanocrystals via the Dynamic Volume of Chain Segments
Authors: Cao Weicheng , Pang Zhenfeng , Zhou Xiaoqi , Cao Zhenming , Li Jiachen , Wang Qi , Peng Xiaogang , Kong Xueqian
Published: April 2022

The intermolecular ligand-ligand interaction is crucial for the surface chemistry, solution properties, and self-assembly processes of colloidal nanocrystals (NCs). The studies on the ligand-ligand interaction are hampered by the disordered and dynamic nature of the surface, the low electron contrast of organic moieties, and the non-characteristic weak intermolecular forces. Solid-state nuclear magnetic resonance (NMR) can provide site-specific information on organic ligands and especially the motional behavior of chain segments. In this work, we develop an advanced solid-state NMR measurement and modelling strategy to quantify the “dynamic volume” of chain segments. The dynamic volume depicts the accessible space of a chain segment under the confinement of neighboring molecules, and is inversely proportional to the intermolecular interaction energy. The ligand-ligand interaction energies have been obtained for NCs with alkanoate ligands of different lengths. We show that the calculated ligand-ligand interaction energy determines solution dispersity and the melting transitions of NCs. This dynamic volume concept can be extended beyond experimental NMR measurements and offer semi-empirical predictions of the interaction energies for arbitrary selections of alkanoate ligands. Our study not only advances the quantitative understanding of ligand-ligand interaction on NCs but also establishes novel tactics to calibrate weak intermolecular interactions.
Halide Perovskites as Disposable Epitaxial Templates for the Phase-Selective Synthesis of Lead Sulfochloride Nanocrystals
Authors: Toso Stefano , Imran Muhammad , Mugnaioli Enrico , Moliterni Anna , Caliandro Rocco , Schrenker Nadine J. , Pianetti Andrea , Zito Juliette , Zaccaria Francesco , Wu Ye , Gemmi Mauro , Giannini Cinzia , Brovelli Sergio , Infante Ivan , Bals Sara , Manna Liberato
Published: April 2022

Colloidal chemistry grants access to a wealth of materials through simple and mild reactions. However, even few elements can combine in a variety of stoichiometries and structures, potentially resulting in impurities or even wrong products. Similar issues have been long addressed in organic chemistry by using reaction-directing groups, that are added to a substrate to promote a specific product and are later removed. Inspired by such approach, we demonstrate the use of CsPbCl3 perovskite nanocrystals to drive the phase-selective synthesis of two novel lead sulfochlorides: Pb3S2Cl2 and Pb4S3Cl2. When homogeneously nucleated in solution, lead sulfochlorides form Pb3S2Cl2 nanocrystals. Conversely, the presence of CsPbCl3 triggers the formation of Pb4S3Cl2/CsPbCl3 epitaxial heterostructures. The phase selectivity is guaranteed by the continuity of the cationic subnetwork across the interface, a condition not met in a hypothetical Pb3S2Cl2/CsPbCl3 heterostructure. The perovskite domain is then etched, delivering phase-pure Pb4S3Cl2 nanocrystals that could not be synthesized directly.
Enhanced Sampling Aided Design of Molecular Photoswitches
Authors: Raucci Umberto , Sanchez David M. , Martinez Todd J. , Parrinello Michele
Published: April 2022

Advances in the evolving field of atomistic simulations provide continuous insights for the design and fundamental understanding of novel molecular photoswitches. Here, we use state-of-the-art enhanced simulation techniques to unravel the complex, multistep chemistry of donor-acceptor Stenhouse adducts (DASAs), revealing a plethora of newly discovered thermal pathways. We use enhanced sampling simulations to drive reaction discovery, followed by refinement of newly observed pathways with more accurate ab initio electronic structure calculations, and then structural modifications to introduce design principles in new generations of DASAs. We illustrate tunability of these newly discovered reactions, leading to a potential avenue for controlling DASA dynamics through multiple external stimuli. Overall, these insights could offer alternative routes to increase the efficiency and control of DASA’s photoswitching mechanism, providing new elements to design more complex light-responsive materials.
Umbrella Sampling Simulations Simultaneously Measure Switch Peptide Binding and Hydrophobic Patch Opening Free Energies in Cardiac Troponin
Authors: Cool Austin , Lindert Steffen
Published: April 2022

The cardiac troponin complex (cTn) is an important regulatory protein in heart contraction. Upon binding of Ca2+, cTn undergoes a conformational shift that allows the troponin I switch peptide (cTnISP) to be released from the actin filament and bind to the troponin C hydrophobic patch (cTnC). Mutations and modifications to this complex can change its sensitivity to Ca2+ and alter the energetics of the transition from the Ca2+-unbound, cTnISP-unbound form to the Ca2+-bound, cTnISP-bound form. We utilized targeted MD (TMD) to obtain a trajectory of this transition pathway, followed by umbrella sampling to estimate the free energy associated with the cTnISP-cTnCHP binding and the cTnCHP opening events for wild-type (WT) cTn. We were able to reproduce experimental values for the cTnISP-cTnCHP binding event and obtain cTnCHP opening free energies in agreement with previous computational measurements of smaller cTnC systems. This excellent agreement for WT cTn demonstrated the strength of computational methods in studying the dynamics and energetics of cTn complex. We then introduced mutations to the cTn complex that cause cardiomyopathy or alter its Ca2+-sensitivity and observed a general decrease in the free energy of opening the cTnCHP. For these same mutations, we observed no general trend in the effect on the cTnISP-cTnCHP binding event. Our method sets the stage for future computational studies on this system that predict the consequences of yet uncharacterized mutations on cTn dynamics and energetics.
Expediency of immunocytochemical study as a marker of proliferative activity in cervical intraepithelial neoplasia
Authors: Pestrikova Tatyana Yu. , Ismaylova Ainur F.
Published: April 2022

Aim. To assess the feasibility of using immunocytochemical studies as a marker of proliferative activity in cervical intraepithelial neoplasia.
Materials and methods. A comprehensive examination of 78 women, aged 25 to 45 years, with the presence of cervical intraepithelial neoplasia was carried out. Verification of the diagnosis was carried out on the basis of data from clinical, cytological, colposcopic, histological studies. Human papillomavirus typing was carried out using the polymerase chain reaction method (Kvant 21 test).
Results. The results obtained in our study indicate that in patients with CIN II, III, chronic cervicitis associated with human papillomavirus (HPV) is an obligatory background pathology. Regardless of the severity of cervical dysplasia (CIN IIIII), among the various types of HPV, HPV type 16 and associations of various HPV types of high oncological risk prevailed (41.03 and 25.64%, respectively). The HPV load result was expressed in decimal logarithms (Lg). Co-expression of p16ink4a oncoprotein and proliferative activity marker Ki-67 in epithelial cells was observed at viral load parameters of 35 Lg in 64.10% of cases, and at values of 5 Lg in 100% of cases.
Conclusion. Our data indicate the need for wider use of non-invasive determination of markers р16ink4a and Ki-67 during primary screening, which will improve the tactics of managing patients with cervical precancer. Persistent course of human papillomavirus in patients with cervical intraepithelial neoplasia II in the presence of signs of coexpression of p16ink4a and Ki-67 dictates the inexpediency of performing cervical excision with subsequent control after 6 months.
Study of pulmonary arterial hypertension in patients of chronic kidney disease stage IV and V
Authors:   Senior Resident, Department of General Medicine, Sri Siddhartha Institute Of Medical Sciences And Research Centre, T. Begur, Nelamangala Taluk, Bangalore Rural District, Karnataka, INDIA., B Sohan
Published: April 2022

Background: Pulmonary arterial hypertension (PAH) in advanced CKD patients (stage 4/5) is important to recognize, as PAH is an independent predictor of mortality in CKD patients especially those receiving renal replacement therapy and significant PH is felt to be a relative contraindication to renal transplantation. Present study was aimed to study Pulmonary Arterial Hypertension in Patients of Chronic Kidney Disease Stage 4/5 at a tertiary hospital. Material and Methods: Present study was cross-sectional, prospective and observational study, conducted patients Age ≥18 years, of either gender, diagnosed case of CKD in stage IV and stage V, underwent evaluation for PAH by echocardiography. Results: In present study, total 68 patients were included. Mean age in study was 51.93 ± 12.63 years. Male patients (73.53 %) outnumbered female patients (26.47 %). Associated Co-morbidities in present study were anemia (70.59 %), diabetes mellitus (57.35 %), systolic hypertension (32.35 %) and diastolic hypertension (26.47 %). majority of patients had stage 4 CKD (69.12 %). Mean duration of CKD was 43.11 + 26.78 weeks while mean duration of dialysis was 21.45± 15.74 weeks. 61.76 % patients had attained Dry weight in present study. In present study, incidence of pulmonary hypertension was 51.35 %. In patients with pulmonary hypertension most common etiology for CKD were diabetes mellitus (34.29%), hypertension (31.43 %), undetermined (17.14 %). In present study 47 patients (69.12 %) had stage 4 CKD. Among stage 4 patients mild PH was noted in 11 patients (16.18 %), while moderate and severe PH was noted in 4 (5.88 %) and 2 (2.94 %) patients respectively. While 21 patients (30.88 %) had stage 5 CKD. Among stage 5 patients mild PH was noted in 7 patients (10.19 %), while moderate and severe PH was noted in 5 (7.35 %) and 4 (5.88 %) patients respectively. Conclusion: Higher incidence of pulmonary hypertension is noted among chronic kidney disease and incidence increases with advanced stages.
Early Detection of Mental Disorders and Psychosocial Problems in Students Taking Online Learning during COVID-19 Pandemic
Authors: Trishinta Sirli Mardianna , Hastutiningtyas Wahidyanti Rahayu , Rosdiana Yanti
Published: April 2022

The online problems impact from online learning faced by students if not handled immediately will lead to the impact of mental disorders and psychosocial problems that are bigger and more serious. The aim of this study is to conducted early detection of mental disorders and psychosocial problems in nursing students who run online clinical practices during the COVID-19 pandemic at Tribhuwana Tunggadewi University, Malang. This research uses descriptive research with a cross-sectional study approach. That is, data between the independent and dependent variables collected at the same time. The population in this study were all students at Tribhuwana Tunggadewi University Malang, class of 2016, as many as 276 people. Sampling in this study is the total sampling technique is the overall sampling technique. This research used Chi square analytics to test the hypothesis. Result of this study shows that gender is significantly associated with psychological problems (p = 0.038), while gender has no relationship with the use of psychoactive use (p = 0.789), and PTSD (p = 0.551). It is concluded that mental disorders and psychosocial problems (i.e., psychological problem, psychoactive use, PTSD and unidentified psychologicaly) were prevalent among nursing students who run online clinical practice at Tribhuwana Tunggadewi. Studentsâ€™ gender are associated with psychological problems, while has no associated with psychoactive use and PTSD. This study recommend that faculty authority, health professionals, and other professional related to mental health should play an important role for the prevention and earlier recognition of and intervention for psychosocial problems in nursing students who run online clinical practice during the COVID-19 pandemic.
Determinants of Smoking Behavior in Adolescents
Authors: Sumiatin Titik , Ningsih Wahyu Tri , Su'udi Su'udi , Rofiâ€™i Aby Yazid Al Busthomy
Published: April 2022

Smoking behavior as one of the riskiest behaviors carried out by teenagers has always been a problem throughout the ages. As long as the root cause is still there and supported by various policies that are in favor of the owners of the cigarette industry, during that time the problem of smoking will always exist. One of the districts in East Java with the highest number of smokers is Tuban. This study aims to determine what factors are the most dominant influencing adolescent smoking behavior in Tuban Regency. The population in this study were junior high school youth in the district of Tuban, both smokers and non-smoker. The design in this study was analytic with a Cross-Sectional approach. The population was junior high school youth, both male and female, totaling 2,866, with a sample size of 287 using purposive sampling. The independent variables in this study were gender, puberty status, self-esteem, motivation, health status, work, economy, environment, friends, family, models/role models. Data was collected using a questionnaire compiled by the research team using the Pender Model theory approach. The collected data was analyzed by logistic regression test. The results showed that most of the adolescents did not smoke by 98.61%, more than half of the adolescents were female (58.89%), almost all of them had experienced puberty (96.17%), most of them had negative self-esteem (88.50%), all of whom stated that smoking did not motivate to do activities, all of them stated that they did not smoke during their illness, almost all of them did not have a side job (97.56%), more than half of the parents had income above the minimum wage (53.31%), almost all stated that the environment did not affect smoking behavior (99.30%), almost all stated that friends did not influence smoking behavior (98.95%), almost all stated that family did not influence smoking behavior (99.65%), and almost all stated that their model/role model did not affect smoking behavior (99.65%). Based on the results of statistical tests, it was found that all factors had a significance > 0.05 so that there were no factors that significantly influenced smoking behavior in adolescents or in other words there was no dominant factor that significantly affected smoking behavior in adolescents in Tuban district. For related parties such as schools, the health office, health education participate in maintaining and continuing to improve education to adolescents about the dangers of smoking so that adolescents do not engage in behaviors that are more risky to health than the benefits obtained.