bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Construction of Chiral Quaternary Carbon Centers via Palladium‐Catalyzed Asymmetric Deconjugative Allylation.
Authors: Yamamoto Hiroki , Oonishi Yoshihiro , Sato Yoshihiro
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Divergent Enantioselective Pathways in the Catalytic Asymmetric Addition of Diethylzinc to Aldehydes in the Presence and Absence of Titanium Tetraisopropoxide.
Authors: Dean Melissa A. , Hitchcock Shawn R.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reduction of Carbon—Carbon Double Bonds Using Organocatalytically Generated Diimide.
Authors: Smit Christian , Fraaije Marco W. , Minnaard Adriaan J.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Triphenylarsinyl‐Functionalized N‐Heterocyclic Carbene Ligands in Palladium‐Catalyzed C—C Coupling Reactions.
Authors: Stiemke Frank , Gjikaj Mimoza , Kaufmann Dieter E.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Strategy for Chemoselective O‐Acylation of β‐Mercapto Alcohols via Alkylsilyl and Stannyl Protection.
Authors: Maheswara Muchchintala , Kim Mirae , Yun Sun‐Ju , Ju Jung Jin , Do Jung Yun
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Degradable Dendrimers Divergently Synthesized via Click Chemistry.
Authors: Kohman Richie E. , Zimmerman Steven C.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalyst‐Free Aldol Additions of 1,3‐Dicarbonyl Compounds.
Authors: Rohr Kerstin , Mahrwald Rainer
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Simple, Efficient and Versatile Synthesis of Primary gem‐Dihydroperoxides from Aldehydes and Hydrogen Peroxide.
Authors: Bunge Alexander , Hamann Hans‐Juergen , Liebscher Juergen
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intermolecular Reaction of Internal Alkynes and Imines: Propargyl Tosylates as Key Partners in a Gold‐Catalyzed [4 + 1] Unusual Cyclization Leading to Cyclopent‐2‐enimines.
Authors: Suarez‐Pantiga Samuel , Rubio Eduardo , Alvarez‐Rua Carmen , Gonzalez Jose M.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Diastereoselective Zn/SnCl2‐Mediated gem‐Difluoroallylation of Chiral Hydrazones.
Authors: Yue Xuyi , Zhang Xingang , Qing Feng‐Ling
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aminolysis of Epoxides in Ionic Liquid 1‐Ethylpyridinium Trifluoroacetates as Green and Efficient Reaction Medium.
Authors: Malhotra Sanjay V. , Andal Richard P. , Kumar Vineet
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkylpalladium N‐Heterocyclic Carbene Complexes: Synthesis, Reactivity, and Catalytic Properties.
Authors: Esposito Oriana , Gois Pedro M. P. , de K. Lewis Alexandra K. , Caddick Stephen , Cloke F. Geoffrey N. , Hitchcock Peter B.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Camphorsulfonamide‐Based Quinoline Ligands and Their N‐Oxides: First Use in the Enantioselective Addition of Organozinc Reagents to Aldehydes.
Authors: Martinez Ricardo , Zoli Luca , Cozzi Pier Giorgio , Ramon Diego J. , Yus Miguel
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel and Efficient Procedure for the Preparation of Allylic Alcohols from α,β‐Unsaturated Carboxylic Esters Using LiAlH4/BnCl.
Authors: Wang Xiaolong , Li Xiaodong , Xue Jijun , Zhao Yuling , Zhang Yumei
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Synthesis of (‐)‐Ritodrine Hydrochloride (V) via Silyl Enol Ether Amination Using Dirhodium(II) Tetrakis [Tetrafluorophthaloyl‐(S)‐tert‐leucinate].
Authors: Tanaka Masahiko , Nakamura Seiichi , Anada Masahiro , Hashimoto Shunichi
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Organo‐Singly Occupied Molecular Orbital Catalysis: The Carbo‐oxidation of Styrenes.
Authors: Graham Thomas H. , Jones Casey M. , Jui Nathan T. , MacMillan David W. C.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2‐(N‐Hydroxylamino) Sulfone Synthesis by Indium—Iodine‐Triggered Aza‐Michael Type Addition of Nitroarenes to Vinyl Sulfones.
Authors: Lee Sun Jung , Lee Jung June , Kim Chong‐Hyeak , Jun Young Moo , Lee Byung Min , Kim Byeong Hyo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Guanylation of Aromatic Amines Catalyzed by Samarium Diiodide.
Authors: Zhu Xuehua , Xu Fan , Shen Qi
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis and Catalytic Activity of the Iridium(I) Hydroquinone Complex [(H2Q)Ir(COD)]+.
Authors: Kim Sang Bok , Cai Chen , Faust Marcus D. , Trenkle William C. , Sweigart Dwight A.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Conjugate Addition of Unmodified Cyclic Ketones to Nitroolefins Using Aminophosphonate as the Organocatalyst.
Authors: Chen Gang , Wang Zheng , Ding Kuiling
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Versatile Chiral Building Blocks from D‐Xylose.
Authors: Zhen Zhibin , Gao Jian , Wu Yikang
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Synthesis of 1,2‐Thiazetidines of anti‐ and syn‐9,9′‐Bibenzonorbornenylidenes.
Authors: Sugihara Yoshiaki , Takeda Ken‐ichi , Zhao Jin , Aoyama Yui , Okuda Harunori , Nakayama Juzo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Ruthenium‐Catalyzed, Atom‐Economical Synthesis of Nitrogen Heterocycles.
Authors: Trost Barry M. , Maulide Nuno , Livingston Robert C.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Synthesis of the Antiepileptic Drug Levetiracetam.
Authors: Imahori Tatsushi , Omoto Keisuke , Hirose Yumi , Takahata Hiroki
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regioselective Synthesis of Either 1H‐ or 2H‐1,2,3‐Triazoles via Michael Addition to α,β‐Unsaturated Ketones.
Authors: Kwok Sen Wai , Hein Jason E. , Fokin Valery V. , Sharpless K. Barry
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Fluorous Thiazolium Salts for the Intramolecular Stetter Reaction.
Authors: Hara Osamu , Kume Atsuko , Sugiura Michiharu , Maeba Isamu
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The First Organocatalyst‐Mediated Enantioselective Substitution of Racemic Iodoalkanes under Radical Conditions.
Authors: Murakata Masatoshi , Jono Toshiaki , Shoji Tetsuya , Moriya Akiko , Shirai Yoko
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Multicomponent Reaction for the Synthesis of Piperidine Derivatives: Yb(OTf)3/AgOTf Cocatalyzed Preparation of Trimethyl 3,5,5‐Piperidonetricarboxylate.
Authors: Lian Gao‐Yan , Lin Feng , Yu Jin‐Di , Zhang Dan‐Wei
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Friedlaender Synthesis of Poly‐Substituted Quinolines in the Presence of Dodecylphosphonic Acid (DPA) as a Highly Efficient, Recyclable and Novel Catalyst in Aqueous Media and Solvent‐Free Conditions.
Authors: Ghassamipour S. , Sardarian A. R.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of 8‐(2‐((Trimethylsilyl)ethynyl)phenylamino)‐7H‐naphtho [1,8‐bc]acridin‐7‐one.
Authors: Li Lidong , Gomes Clara S. B. , Gomes Pedro T. , Duarte M. Teresa
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Free Syntheses of Some Quinazolin‐4(3H)‐ones Derivatives.
Authors: Roopan S. Mohana , Maiyalagan T. , Khan F. Nawaz
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cyclocondensation of N‐Aryl‐3‐oxobutanethioamides with 2‐Aminoimidazole and 2‐Aminobenzimidazole.
Authors: Maiboroda E. I. , Britsun V. N.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Verticillane‐Type Diterpenoids from the Taiwanese Soft Coral Cespitularia hypotentaculata
Authors: Cheng Yuan‐Bin , Lo Kuang‐Liang , Chen Ching‐Yeu , Khalil Ashraf Taha , Shen Ya‐Ching
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, from Phyllanthus engleri.
Authors: Ratnayake Ranjala , Covell David , Ransom Tanya T. , Gustafson Kirk R. , Beutler John A.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Dieckmann Condensation via Memory of Chirality: Synthesis of the Key Intermediate for AS‐3201, an Aldose Reductase Inhibitor.
Authors: Watanabe Toshihide , Kawabata Takeo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Synthesis of Optically Active Biopterin (IV).
Authors: Shiro Yuichi , Urano Fumi , Kuroda Yasuhiro , Murata Shizuaki
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chaetomugilins, New Selectively Cytotoxic Metabolites, Produced by a Marine Fish‐Derived Chaetomium Species.
Authors: Yasuhide Muroga , Yamada Takeshi , Numata Atsushi , Tanaka Reiko
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Facile Synthesis of Fe2O3 Nanocrystals Without Fe(CO)5 Precursor and One‐Pot Synthesis of Highly Fluorescent Fe2O3—CdSe Nanocomposites.
Authors: Ang Chung Yen , Giam Louise , Chan Zheng Ming , Lin Alex W. H. , Gu Hongwei , Devlin Eamonn , Papaefthymiou Georgia C. , Selvan Subramanian Tamil , Ying Jackie Y.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Advances in the Coordination Chemistry of Amidinate and Guanidinate Ligands
Authors: Edelmann Frank T.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Methods for the Synthesis of Cinnolines
Authors: Vinogradova O. V. , Balova I. A.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organic Chemosensors with Crown‐Ether Groups
Authors: Tsukanov A. V. , Dubonosov A. D. , Bren V. A. , Minkin V. I.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: William von Eggers Doering′s Many Research Achievements During the First 65 Years of his Career in Chemistry
Authors: Klaerner Frank‐Gerrit , Jones Maitland Jr. , Magid Ronald M.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of New Method for Molecular Biology Using the Photophore, Diazirine
Authors: Sadakane Yutaka , Hatanaka Yasumaru
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Photocatalytic Transformations of Organic Sulfur Compounds and H2S
Authors: Vorontsov A. V.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Naturally Diverse: Highlights in Versatile Synthetic Methods Enabling Target‐ and Diversity‐Oriented Synthesis
Authors: Shaw Jared T.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Light in Aminocatalysis: The Asymmetric Intermolecular α‐Alkylation of Aldehydes
Authors: Melchiorre Paolo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of PEGylated Adenovirus Vector for Cancer Gene Therapy
Authors: Eto Yusuke , Yoshioka Yasuo , Asavatanabodee Ratima , Mizuguchi Hiroyuki , Mukai Yohei , Okada Naoki , Nakagawa Shinsaku
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Expressed Protein Ligation (EPL) in the Study of Signal Transduction, Ion Conduction, and Chromatin Biology
Authors: Flavell Robert R. , Muir Tom W.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multifunctional Nanostructured Materials for Multimodal Imaging, and Simultaneous Imaging and Therapy
Authors: Kim Jaeyun , Piao Yuanzhe , Hyeon Taeghwan
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 19F NMR Applications in Chemical Biology
Authors: Cobb Steven L. , Murphy Cormac D.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Acute Effects of Smoking Light Cigarettes on Coronary Microvascular Functions
Authors: Ciftci Ozgur , Caliskan Mustafa , Gullu Hakan , Erdogan Dogan , Topcu Semra , Guler Ozgen , Yildirir Aylin , Muderrisoglu Haldun
Published: April 2009

Background

To date, there has been no study comparing the possible acute effects on coronary microvascular functions of smoking light cigarettes (those with low tar and nicotine yield) and regular cigarettes.

Methods

Twenty healthy volunteers (8 women and 12 men; mean age, 25.8 ± 5.8 years) were included in a single‐blind, open‐label, cross‐over study to compare the effects of smoking light cigarettes (containing 0.6 mg nicotine, 8 mg tar, 9 mg carbon monoxide) and smoking regular cigarettes (containing 0.9 mg nicotine, 12 mg tar, 12 mg carbon monoxide) on coronary flow reserve (CFR). For each participant, CFR values were measured at baseline, after smoking 2 regular or light cigarettes, and 15 days later after smoking 2 cigarettes of the other kind.

Results

After smoking 2 cigarettes, CFR values declined from 2.8 ± 0.56 (baseline) to 2.31 ± 0.51 after smoking light cigarettes (P = .003), and from 2.8 ± 0.56 (baseline) to 2.21 ± 0.45 after smoking regular cigarettes (P < .001). After smoking light and regular cigarettes, CFR values were similar (P = .678).

Conclusions

Light cigarette smoking has similar acute detrimental effects on coronary microvascular function and CFR as does regular cigarette smoking. Copyright © 2009 Wiley Periodicals, Inc.
Impact of Acute Serum Creatinine Elevation in Patients Treated with Nesiritide
Authors: Elkayam Uri , Janmohamed Munir , Hatamizadeh Parta , Heywood J. Thomas , Wei Lee‐Jen , Mills Roger M.
Published: April 2009

Background

We assessed the effect of increases in serum creatinine on mortality in nesiritide‐treated versus control subjects with acute decompensated heart failure (ADHF).

Hypothesis

Mortality effect of nesiritide‐related increases in serum creatinine differs from that of standard therapies.

Methods

Scios Inc., granted unrestricted access to data from all 5 randomized, controlled nesiritide infusion trials completed to date in patients hospitalized with ADHF. We used 2 different definitions of acute serum creatinine increase: >0.3 mg/dL and > 0.5mg/dL within 30 days of study enrollment and determined 30‐day mortality risk for nesiritide‐treated versus control subjects utilizing each definition.

Results

A total of 1,270 subjects participated in the 5 trials. A >0.3 mg/dL increase in serum creatinine was associated with a significant increase in mortality risk in control subjects, (hazard ratio [HR]: 3.47, 95% confidence interval [CI]: 1.49–8.09) but not in nesiritide‐treated subjects (HR: 1.65, 95% CI: 0.90–3.05). Results were similar for a >0.5 mg/dL increase (control HR: 5.12, 95% CI: 2.09–12.57 and nesiritide HR: 1.77, 95% CI: 0.90–3.51). In subjects with >0.3 mg/dL and >0.5 mg/dL increases in serum creatinine, respectively, the 30‐day mortality odds ratios for nesiritide relative to control were 0.73 (95% CI: 0.29–1.93) and 0.52 (95% CI: 0.17–1.63) using a stratified Mantel‐Haenszel analysis.

Conclusions

The impact of increased serum creatinine on mortality was attenuated in nesiritide‐treated patients compared to control, suggesting that the mechanism and clinical significance of increases in serum creatinine associated with nesiritide treatment may differ from those associated with standard therapies. Further investigation is warranted. Copyright © 2009 Wiley Periodicals, Inc.
Sensitization of Cancer Cells for Chemo/Immuno/Radio‐therapy. Edited by Benjamin Bonavidia.
Authors: Kotake Yoshihiko
Published: April 2009

Humana Press, Totowa 2008. xxi+419 pp., hardcover $ 159.00.—ISBN 978‐1‐93411‐529‐9

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Inside Cover: Development of Novel Thiazolopyrimidines as CDC25B Phosphatase Inhibitors (ChemMedChem 4/2009)
Authors: Kolb Stéphanie , Mondésert Odile , Goddard Mary‐Lorène , Jullien Denis , Villoutreix Bruno O. , Ducommun Bernard , Garbay Christiane , Braud Emmanuelle
Published: April 2009

The inside cover picture shows a possible docking pose of a thiazolopyrimidine ligand (stick representation) in the active site of CDC25 shown as a ribbon diagram. The dioxolane moiety is located in the catalytic site loop whereas the dibromohydroxyphenyl part is pointing toward the adjacent “swimming pool”. For more details, see the Full Paper by E. Braud et al. on p. 633 ff.

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Combined Online Spectroscopic, Calorimetric, and Chemometric Analysis: Reaction Enthalpy Determinations in Single and Parallel Reactions
Authors: Tjahjono Martin , Widjaja Effendi , Garland Marc
Published: April 2009

Calorimetry and signal processing: Vibrational spectroscopies, heat‐flow microcalorimetry, and multivariate analysis are combined to decouple the reaction enthalpies of parallel reactions (see picture). This methodology allows the evaluation of reaction enthalpy from complex systems without recourse to conventional kinetic modeling.

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Simultaneous in situ/online spectroscopy and heat‐flow measurements as well as multivariate analyses are performed, apparently for the first time, to determine heats of reaction for single and parallel reactions. Two different vibrational spectroscopy techniques, namely Raman and FTIR spectroscopy, are used in conjunction with flow‐through TAM III microcalorimetry. With respect to the spectroscopic analysis, the reaction spectra are first analyzed to determine the pure‐component spectra and the corresponding concentrations without recourse to external calibration. With respect to the calorimetric analysis, a soft modeling approach is employed to determine the heats of reaction without recourse to any conventional kinetic models. This combined approach is implemented to determine the extents of reaction as well as the corresponding heats of reaction at 298.15 K and 0.1 MPa for a) the hydrolysis of acetic anhydride (single reaction) and b) the hydrolysis of methyl paraben and ethyl paraben in alkaline solution (both single and parallel reactions). In the latter case, the heat‐flow contributions from the two simultaneous reactions are successfully decoupled. Taken together, these results demonstrate proof of concept for the present approach. The newly developed methodology appears to be quite general and particularly useful for investigating complex reaction systems. This is particularly true for multiple simultaneous reactions and reactions where the detailed kinetic expressions are not available, or cannot be easily determined. The use of extents of reaction is also very helpful where there is high variability in reaction rates, that is, due to the presence of impurities, changes in catalyst activity, or concentrations, temperature, and pH.
Catalytic Applications in the Production of Biodiesel from Vegetable Oils
Authors: Sivasamy Arumugam , Cheah Kien Yoo , Fornasiero Paolo , Kemausuor Francis , Zinoviev Sergey , Miertus Stanislav
Published: April 2009

Fat Cats: The production of biodiesel from vegetable oils and animal fats through transesterification and cracking is an emerging sector of the modern chemical industry, which, as many others, relies on the use of catalysis. Recent advances in the application of various homogeneous, heterogeneous, and enzymatic catalytic systems to biofuel production are presented in this Review.

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The predicted shortage of fossil fuels and related environmental concerns have recently attracted significant attention to scientific and technological issues concerning the conversion of biomass into fuels. First‐generation biodiesel, obtained from vegetable oils and animal fats by transesterification, relies on commercial technology and rich scientific background, though continuous progress in this field offers opportunities for improvement. This Review focuses on new catalytic systems for the transesterification of oils to the corresponding ethyl/methyl esters of fatty acids. It also addresses some innovative/emerging technologies for the production of biodiesel, such as the catalytic hydrocracking of vegetable oils to hydrocarbons. The special role of the catalyst as a key to efficient technology is outlined, together with the other important factors that affect the yield and quality of the product, including feedstock‐related properties and various system conditions.
Thermodynamic Properties of Dusty Plasma on the Basis of the Langevin Dynamics
Authors: Ramazanov T. S. , Dzhumagulova K. N. , Kodanova S.K. , Daniyarov T. T. , Dosbolayev M. K.
Published: April 2009

Radial distribution functions of dusty plasma particles are calculated by the application of the Langevin dynamics to a system of particles interacting through the Yukawa potential. Proposed numerical model is first validated by the comparison of the numerical results with available experimental data. Both numerically determined and experimental radial distribution functions demonstrate a good coincidence, thus, enabling a calculation of the structural properties of dusty plasma for a wide range of parameters. On the basis of the performed calculations, dependencies of internal energy and excess pressure from the coupling and density parameters are presented (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Negative Ions in Helicon Oxygen Discharges
Authors: Sydorenko N. , Grulke O. , Matyash K. , Schneider R. , Ullrich S. , Klinger T.
Published: April 2009

The negative oxygen ion density is studied experimentally in the high‐density helicon device VINETA by laserinduced photodetachment. The measurements indicate a negative ion density being higher than the electron density in contrast to previous experiments in helicon oxygen discharges. The dependency of the relative negative ion density on the oxygen gas pressure and rf‐power is in good qualitative agreement with observations in low temperature RF inductive and capacitive discharges, but differ quantitatively by one order of magnitude. To understand the basic physics in the helicon discharges, the measurements are compared to a zero dimensional reaction rate model of the electronegative oxygen discharge. The particle densities are calculated via rate equations estimated fromcollisional cross sections assumingMaxwellian electron energy distribution functions. The model shows that the electron temperature is the most sensitive parameter governing the formation of negative oxygen ions. Additionally, the differences to previous experimental measurements in rf discharges can be explained by different electron temperature and plasma losses to the walls (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Analytical Evaluation of the Plasma Dispersion Function Using Binomial Coefficients and Incomplete Gamma Functions
Authors: Mamedov B.A.
Published: April 2009

Series expansions are obtained for a plasma dispersion function that appears in the description of smallamplitude waves in very hot plasmas. However, the numerical implementation of this function is required in diverse areas of physics and applied mathematics. An explicit representation for the plasma dispersion function is developed in terms of series of binomial coefficients and incomplete gamma functions. The series expansions obtained herein give a more accurate and efficient way to compute values for this integral over the entire permissible range of its parameters. The results of the calculations are compared with literature data as well as those obtained by different approximate method (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
A new control method of a resonant switched‐capacitor converter and the application for balancing of the split DC voltages in a multilevel inverter
Authors: Sano Kenichiro , Fujita Hideaki
Published: April 2009

This paper proposes a new voltage‐balancing circuit for the split DC voltages in a diode‐clamped five‐level inverter. The proposed circuit is based on a resonant switched‐capacitor converter (RSCC), which consists of two half‐bridge inverters, a resonant inductor, and a resonant capacitor. A new phase‐shift control of the RSCC is proposed to improve voltage balancing performance. Theoretical analysis reveals the rating of the RSCC and stored energy in the resonant inductor. Experimental results confirm the reduction of the inductor to one‐tenth in volume compared to a conventional voltage‐balancing circuit based on buck‐boost topology. Moreover, the proposed phase‐shift control has demonstrated that it is possible to eliminate the voltage deviation between the DC capacitors. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 168(2): 69–79, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20719
Adaptive finite element method for shape modification in optimization of electric machines
Authors: Yamazaki Katsumi , Ishigami Hiroki
Published: April 2009

A method for the modification of finite element meshes based on adaptive meshing for optimization of electric machines is proposed. In the optimization of the machine, the proposed method generates the mesh for the new shape from the previous mesh with minor modification. The locations of the nodes for the new shape are decided by solving a Laplacian equation whose unknowns are the displacements of the nodes. The advantages are illustrated by application to the shape optimization of an IPM motor. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 168(1): 21–28, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20773
Eddy current analysis of thin metal container in induction heating by line integral equations
Authors: Fujit Hagino , Ishibashi Kazuhisa
Published: April 2009

In recent years, induction‐heating cookers have spread rapidly. It is desirable to commercialize flexible and disposable food containers that are suitable for induction heating. In order to develop a good‐quality food container for moderate heating, the eddy currents induced in a thin metal plate must be accurately analyzed. The integral equation method is widely used for solving induction‐heating problems. If the plate thickness approaches zero, the surface integral equations on the upper and lower plate surfaces tend to become the same and the equations become ill‐conditioned. In this paper, we first derive line integral equations from the boundary integral equations under the assumption that the electromagnetic fields in the metal are attenuated more rapidly than those along the metal surface. Next, to test the validity of the line integral equations, we solve for the eddy current induced in a thin metal container in induction heating and obtain the power density imparted to the container and the impedance characteristics of the heating coil. We then compare the computed results with those obtained by the FEM. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 168(2): 20–27, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20813
Solution of the vehicle routing problem for a cooperative logistics network by using multistage GA
Authors: Onoyama Takashi , Maekawa Takuya , Kubota Sen , Tsuruta Setsuo , Komoda Norihisa
Published: April 2009

A GA applied VRP (Vehicle Routing Problem) solving‐method which realizes optimization of a cooperative logistics network is proposed. For this optimization a VRP solving‐method that can obtain a human expert‐level solution, which realizes steady logistics operation, in interactive response time is required. The multistage GA enables one to obtain the accurate solution under both hard and weak time constraints in interactive response time. Moreover, to realize the stable logistics operations, the daily fluctuation of shipping volume is taken into the fitness value of each individual in GA. The experimental result reveals that the proposed method obtains the accurate solution that realizes the stable operation in interactive response time. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 168(2): 28–37, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20855
Sonoelectrochemical Synthesis of Metallic Aluminum Nanoparticles
Authors: Mahendiran Chinnathambi , Ganesan Raman , Gedanken Aharon
Published: April 2009

In this paper, we report for the first time on the room‐temperature preparation of metallic aluminum nanoparticles by the pulsed sonoelectrochemical method. The prepared nanoparticles were characterized by X‐ray diffraction (XRD), high‐resolution scanning electron microscopy, transmission electron microscopy (TEM), and high‐resolution transmission electron microscopy. TEM analysis shows that the prepared aluminum nanoparticles range from 10 to 20 nm in size. The XRD pattern confirms the formation of metallic aluminum nanoparticles. The results show that the sonoelectrochemical technique is a promising method for the fabrication of air‐sensitive metallic nanoparticles that have a high, negative reduction potential.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Anion–π, Lone‐Pair–π, π–π and Hydrogen‐Bonding Interactions in a CuIIComplex of 2‐Picolinate and Protonated 4,4′‐Bipyridine: Crystal Structure and Theoretical Studies
Authors: Biswas Chaitali , Drew Michael G. B. , Escudero Daniel , Frontera Antonio , Ghosh Ashutosh
Published: April 2009

A CuIIcomplex of protonated 4,4′‐bipyridine (Hbyp) and 2‐picolinate (pic), [Cu2(pic)3(Hbyp)(H2O)(ClO4)2], has been synthesised and characterised by single‐crystal X‐ray analysis. The structure consists of two copper atoms that have different environments, bridged by a carboxylate group. The equatorial plane is formed by the two bidentate picolinate groups in one CuII, and one picolinate, one monodentate 4,4′‐bipyridyl ligand and a water molecule in the other. Each copper atom is also weakly bonded to a perchlorate anion in an axial position. One of the coordinated perchlorate groups displays anion–π interaction with the coordinated pyridine ring. The noncoordinated carboxylate oxygen is involved in lone‐pair (l.p.)–π interaction with the protonated pyridine ring. In addition there are π–π and H‐bonding interactions in the structure. Bader's theory of “atoms in molecules” (AIM) is used to characterise the anion–π and l.p.–π interactions observed in the solid state. A high‐level ab initio study (RI‐MP2/aug‐cc‐pVTZ level of theory) has been performed to analyse the anion–π binding affinity of the pyridine ring when it is coordinated to a transition metal and also when the other pyridine ring of the 4,4′‐bipyridine moiety is protonated. Theoretical investigations support the experimental findings of an intricate network of intermolecular interactions, which is characterised in the studied complex, and also indicate that protonation as well as coordination to the transition metal have important roles in influencing the π‐binding properties of the aromatic ring.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Shape‐Switchable Azo‐Macrocycles
Authors: Müri Marcel , Schuermann Klaus C. , De Cola Luisa , Mayor Marcel
Published: April 2009

The synthesis of four shape‐switchable macrocycles comprising different peripheral substituents is described. The macrocycles1–4consist ofm‐terphenyl semicircles interlinked by two azo joints. These macrocycles were assembled from nitro‐functionalizedm‐terphenyl moieties through reductive dimerization. The semicircles were assembled through Suzuki cross‐coupling reactions. The molecular weights of the macrocycles were determined by vapour pressure osmometry, because mass spectrometry failed in the cases of2and3. TheE→Zphotoisomerization reactions were analysed by UV/Vis spectroscopy complemented by1H NMR studies. A very slow thermal back‐reaction indicated considerable stabilization of theZisomer. The reduced efficiency of the thermal back‐reaction probably arises from the reduced degree of freedom due to the mechanical interlinking of the two azo groups. The photostationary state consisted of all‐Z(85 %) and all‐Eisomers (15 %). TheE→Ztransformation induced by irradiation displayed simple exponential kinetics, which indicates pairwise switching of the two azo groups in a macrocycle, at least on the timescale under investigation. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Enzymatic Baeyer–Villiger Oxidation of Benzo‐Fused Ketones: Formation of Regiocomplementary Lactones
Authors: Rioz‐Martínez Ana , de Gonzalo Gonzalo , Torres Pazmiño Daniel E. , Fraaije Marco W. , Gotor Vicente
Published: April 2009

Baeyer–Villiger monooxygenases (BVMOs) are enzymes that are known to catalyse the Baeyer–Villiger oxidation of ketones in aqueous media using O2 as oxidant. Herein, we describe the oxidation of a set of diverse benzo‐fused ketones by three different BVMOs in both aqueous and non‐conventional reaction media. Most of the tested ketones, for example, 1‐tetralone and 1‐ and 2‐indanone, were converted by one of the employed biocatalysts. The catalytic efficiency could be improved by performing the oxidation reactions at a relatively high pH and by adding organic cosolvents. One striking observation is that absolute and complementary regioselectivities were obtained when oxidizing a range of 1‐indanones using two different BVMOs. The conversion of 1‐indanone by 4‐hydroxyacetophenone monooxygenase (HAPMO) results in the formation of the expected lactone, 3,4‐dihydrocoumarin. In contrast, by using a phenylacetone monooxygenase mutein (M‐PAMO), conversion of 1‐indanone leads to the formation of only the unexpected lactone, 1‐isochromanone. This illustrates that by the appropriate choice of BVMO as biocatalyst, the effective and regioselective conversion of a wide range of benzo‐fused ketones is feasible. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)