bluuebunny/crossref_metadata_2025 huggingface dataset:
Una muchacha corre entre caballos
Authors: Compagnucci Ana Paula
Published: February 2025

En la última década y media, la filmografía nacional se inunda de exploraciones formales, críticas y conceptuales realizadas por proyectos que indagan horizontes variados, desde lugares de enunciación periféricos. La construcción de sujetos y espacios provinciales en el cine se complejiza cuando emerge un mayor número de directoras y directores provenientes de provincias distintas a Buenos Aires, tensionando los valores hegemónicos de la cultura metropolitana. Es decir, la aparición de discursos territorializados nos habilita a pensar que las vivencias de quienes habitan un territorio se impregnan en sus obras, a la vez que le proporcionan mundo, diégesis, fundamento sociohistórico y un sistema de relaciones sociales de referencia. Lo que permite imaginar que se inscriben territorios —antes ausentes— en la cultura, cuando generan un mapa de características y modos de ser/estar para el campo social, cultural y académico. Las Mil y Una (2020), segunda película de Clarisa Navas—cineasta correntina— continúa la línea de Hoy Partido a las Tres (2017) al construir una historia que sucede en el litoral argentino, región de donde es originaria, con personajes —provincianos y provincianas— que desafían las lógicas del binarismo de género. Esta película pone en escena el rol social de las mujeres, las problemáticas de la comunidad LGBTQI+, la lógica de la vida pública y privada tensionada por las hipermediatizaciones, el desplazamiento de barrios populares hacia las afueras de las grandes ciudades y las lógicas de la vecinocracia, entre otras; con una profunda crítica social, amor por los sujetos que (re)presenta y transversalizada por una fuerte urdimbre territorial.
Autoría de mujeres latinoamericanas contemporáneas
Authors: Da Silva Oliveira Amanda
Published: February 2025

Este artículo presenta el proceso de creación, crítica y análisis literarios de la producción de narrativas de autoría de mujeres latinoamericanas, en este caso, bra-sileñas. El objetivo de la investigación es la contribución para las discusiones sobre este tema a partir de lo que Hélène Cixous y Nelly Richard definen como «femini-zación de la escritura». Las autoras estudiadas, Eliane Brum, Maria Valeria Rezende, Natalia Borges Polesso, Valesca de Assis y Carla Madeira, presentan escritos y prácticas escriturarias que se constituyen en «prácticas antihegemónicas», cuyas ideas representan la escritura Culturas 18 · Debates y perspectivas de un mundo en cambio «en tensión con», pues actúan como espacios narrativos que subvierten la lógica patriarcal–falocéntrica.
The role of digital addiction and self-efficacy on academic procrastination: A Turkish pre-service teachers’ case
Authors: Börekci Caner , Uyangör Nihat
Published: February 2025

The study examined the relationships between digital addictions, academic self-efficacy, and academic procrastination among pre-service teachers. The sample included 549 pre-service teachers who participated voluntarily, with 412 females and 137 males enrolled in various disciplines. Two models were constructed to investigate these relationships. The initial model showed negative relations between addiction to digital media or tools, academic self-efficacy, and the ability to complete academic tasks on time. Conversely, higher levels of academic self-efficacy decreased academic procrastination. Academic self-efficacy was also found to partially mediate the relationship between digital addiction and academic procrastination. The second model confirmed that addiction to digital media or tools negatively related to pre-service teachers’ ability to complete academic tasks on time. Similar to the first model, higher levels of academic self-efficacy were associated with lower levels of academic procrastination. As a result of the study, strategies based on literature were proposed to help pre-service teachers reduce digital addiction and enhance academic self-efficacy. It is believed that implementing these strategies will help students complete their academic tasks on time and improve their academic performance.
Determining the threshold for variation in indoor temperature reduction capacity of green roofs with different depths in hot and dry climates
Authors: Muhammad Salihu Murtala , Awad Abuhussain Mohammed , Mohammed Elhassan Zeinab Abdallah , Ramadan Abdelhai Nada Mohamed
Published: February 2025

To forestall the dangers of overdesign, initial and maintenance costs, and unnecessary loading on the supporting roof, the study was primarily aimed at determining the significant difference in indoor temperature reduction capacity between various green roof models of varying thicknesses within the extensive green roof category. Using a contextualized substrate layer of 25mm as the difference in depth between green roof alternatives, the degree of thermal insulation for the interior was observed on six extensive green roof models of 50mm, 75mm, 100mm, 125mm, and 150mm thicknesses. This is to elucidate the level of significant differences in thermal efficiency between the models.  EnergyPlus 8.3.0 simulation software was used to conduct a thermal performance survey on the sampled models.  The temperature profiles of all the cases were collected and subjected to statistical analysis using SPSS V 21.0 to conduct an ANOVA and a proceeding Post hoc test to determine where the difference lies between the green roof groups. The results revealed that; no substantial difference in thermal performance exists between alternatives where the difference in depth is around the 25mm mark. Revealing that the threshold for any significant change in thermal insulation is denoted by a 50mm difference between alternatives. This research was carried out to facilitate the initial process of green roof selection, design, detailing, and specifications writing for architect engineers, and other stakeholders.
Investigating increasing the level of learning and making students interested in mathematics
Authors: Tashbaevich Nurmanov Abdinazar , Javohir Gaybullo Ugli Zokirov , Suluv Khurramovna Sullieva , Zebiniso Kabilova , Sevara Primkulova , Kurbonalijon Gaybullo Ugli Zokirov
Published: February 2025

The research in question is the lack of interest, inattention, and passivity of students in carrying out mathematics activities and the unsatisfactory results of the tests. The purpose of this research was to increase the level of interest of students in mathematics and create motivation and interest in mathematics. The article is a method analysis type and to collect the contents of this research, school experiences and also a review of previous research were used. It is no secret to any of the mathematics activists in the field of education that many students are not interested in mathematics and have problems learning it. In this regard, this research has presented methods for creating motivation in learning mathematics based on the experiences of different schools. By conducting this research, I first identified the causes of students' lack of interest in mathematics and then, by benefiting from the points of view of teachers and parents, books and magazines, experiences, and innovative ways, increased students' interest in mathematics. For this purpose, by using various and modern teaching methods such as brainstorming, games and mathematics, making teaching aids, as well as implementing projects such as "I Can Do It" projects, "Idea from You" and "A Day in the Hands of Children" and using descriptive evaluation to solve group problems, student participation in the class was increased, and by creating a happy and friendly environment, the feeling of fatigue and monotony in the classroom was eliminated and the desired learning situation was provided. The results showed that accurately identifying the cause of lack of interest in mathematics and providing a combination of the above solutions made students interested in learning mathematical concepts. In the end, it was concluded that using various teaching methods, appropriate to the purpose of each lesson, providing functional activities to students according to individual differences, students' needs and interests and appropriate encouragement, strengthening visual and auditory memory, and cultivating learners' accuracy and attention in the form of purposeful games, has been very effective in increasing students' interest in mathematics and performing their functional activities.
Chatbots and crisis communication: effectiveness and limitations in the educational sector
Authors: BaaJ Kaoutar , El Bakkali EL Arbi , Amine Lahiala Mohamed
Published: February 2025

Chatbots play an increasingly significant role in crisis communication by providing real-time information and reducing misinformation. This article explores their application in the educational sector, focusing on their effectiveness during crises. The COVID-19 crisis underscored the urgency of robust communication solutions to ensure accurate and timely sharing of information. The educational sector, serving large and diverse populations, faces unique challenges during emergencies. These challenges include the need to quickly and reliably convey information to a wide range of individuals, including students, parents, teachers, and administrative staff. By integrating chatbots, these institutions can enhance user satisfaction by providing immediate and relevant responses while maintaining educational continuity despite disruptions. However, technological and social limitations persist. Challenges such as the accuracy of AI-provided responses, the linguistic and cultural adaptability of chatbots, and user trust need to be addressed. This research proposes solutions to overcome these obstacles by examining various use cases and drawing on empirical study. The findings demonstrate that, while chatbots cannot fully replace human communicators, they are valuable tools for enhancing communication strategies and supporting educational communities during crises. Their ability to deliver real-time updates, reduce misinformation, and offer emotional support makes them indispensable for crisis communication in the educational sector. With proper implementation and continuous improvement, chatbots can play a pivotal role in crisis management, ensuring that educational processes remain uninterrupted and stakeholders receive reliable information and continuous support. This study emphasizes the need for ongoing innovation and research to optimize chatbot technology for crisis communication, making the educational sector more resilient and adaptable to emergency situations.
The evolution of the English language in the internet and social media era
Authors: Huseynova Rena , Aliyeva Narmin , Habibova Konul , Heydarov Rasim
Published: February 2025

The article presents a comprehensive analysis of the impact of the internet on language, elucidating both the positive and negative aspects of this phenomenon. The principal objective is to identify the principal changes occurring in language as a consequence of the influence of digital technologies and social media, and to assess their impact on language culture and communication. The article provides a comprehensive overview of the Internet’ impact on language, encompassing both positive and negative aspects of this impact. The positive effects include the enrichment of the lexicon, accelerated dissemination of information, and the creation of new forms of communication. Conversely, the negative effects include the simplification of language, the loss of cultural and linguistic features, and the spread of misinformation. Specific focus is given to contemporary trends and developments in online communication, which contribute to the formation of novel communicative norms and etiquette. In light of the accelerated pace of technological advancement and the growing influence of the Internet in our daily lives, it is crucial to examine its impact on language and communication. An understanding of the positive and negative aspects of this impact enables the assessment of how the digital age is changing our language and ways of communication. Furthermore, it facilitates the development of strategies for the preservation of linguistic richness and cultural identity. The article will be of interest to those engaged in the study of language and communication, as well as to a wider audience of readers with an interest in the latest developments in language and technology.
Intercultural communication in crisis: addressing the new wave of Ukrainian emigration
Authors: Berehova Olena , Dutchak Violetta , Karas Hanna , Kukuruza Nadiia , Fedorak Volodymyr
Published: February 2025

The aim of the proposed research is to analyze the dimensions and forms of intercultural communication among figures of musical and theatrical culture within the modern Ukrainian emigration and diaspora, amidst the crisis conditions of the ongoing Russian-Ukrainian war. The focus of this analysis is the creative activity of performers (instrumentalists, vocalists, conductors) – both soloists and ensembles ‑ who play key roles in the process of international communication. The primary timeframe is 2014–2024, covering the various phases of the Russian-Ukrainian war. The study emphasizes terminological aspects of concepts such as “communication”, “culture”, “intercultural communication”, “emigration”, and “refugees”, highlighting their use in contemporary academic discourse. Special attention is given to the strategies and means not only for preserving the national identity of Ukrainian refugees through culture and the arts but also for fostering their intercultural interaction in host countries. In findings, it is emphasized that the Russian-Ukrainian war, even since its hybrid stage from 2014, has resulted in the mass emigration of millions of Ukrainians, marking a new wave of emigration, but artistic professionals in host countries not only preserve their national identity and represent the achievements of Ukrainian culture but also engage in intercultural interaction. Key forms of such interaction include thematic concerts, festivals, theatrical productions, international academic conferences, and collaborative publications.
The political-interactional images: the case of Aziz Akhannouch's government
Authors: Youssef Ouhssou , Khaoula Razmi , Ali Fallous
Published: February 2025

During each interaction, each of the interactants tries to enhance their image in order to protect their territory. This is closely related to pathos, the impact created can be positive or negative, which determines the process of exchange. Indeed, the politician presents themselves to the public in person (deputies, ministers, etc.) or remotely (the people) as an actor who aims for the public/state interest. Their position in the majority or opposition impacts their discursive chain in the context of valuing the governing self and devaluing the opposing other. This political dichotomy and competition disappear when the issue concerns a common objective, essentially, the question of Moroccan Sahara (the personal territory = the Moroccan territory). Henceforth, to understand the functioning of ethos in a political context, we have opted for a pragmatic analysis, namely interactional pragmatics. Saying and doing are intertwined with the aim of carrying out a performative political action, the set of speech acts constituting the conversation determining on the one hand the praise of the self, on the other hand the intended impact of the production.
Enhancing socio-pedagogical engagement in Moodle through AI-driven personalized learning
Authors: Souhaib Aammou , Zakaria Tagdimi , Tarik Touis
Published: February 2025

In the rapidly evolving landscape of digital education, platforms like Moodle have become integral to facilitating learning and fostering student engagement. However, challenges persist in maintaining socio-pedagogical engagement and providing personalized support that caters to the diverse needs of learners. This study introduces an AI-driven system designed to enhance socio-pedagogical engagement within Moodle by delivering personalized messages and recommendations tailored to individual student profiles. Leveraging advanced Artificial Intelligence (AI) and Natural Language Processing (NLP) techniques, the proposed system analyses student interactions, performance metrics, and engagement patterns to generate customized content and communication strategies. The methodology involves the development of AI models trained on a combination of simulated datasets that mirror potential real-world scenarios within educational settings. These models are integrated into the Moodle platform to facilitate dynamic adaptation of learning materials and communication based on individual learner needs. Preliminary evaluations conducted through scenario-based testing indicate a significant potential for the AI-driven system to improve student engagement and learning outcomes. The system demonstrates the ability to identify disengagement early and respond with tailored interventions, thereby fostering a more inclusive and responsive educational environment. Moreover, the personalized recommendations have shown promise in addressing varied learning paces and styles, contributing to a more equitable learning experience. Despite the encouraging preliminary findings, the study acknowledges the limitations posed using fictional data and the need for validation through real-world implementation. Future research will focus on deploying the system within actual educational contexts to assess its efficacy comprehensively. Ethical considerations, particularly concerning data privacy and the handling of sensitive student information, will be paramount in these subsequent phases. This research contributes to the burgeoning discourse on the integration of AI in education, highlighting its potential to revolutionize socio-pedagogical engagement. By tailoring educational experiences to individual learner profiles, AI-driven systems like the one proposed can bridge gaps in engagement and support, paving the way for more personalized and effective digital education. The findings underscore the transformative potential of AI in enhancing educational equity and inclusivity, aligning with the contemporary shift towards learner-centered educational paradigms.
PREDIKSI CALON NASABAH GADAI POTENSIAL PADA PT. PEGADAIAN (PERSERO) MENGGUNAKAN SUPPORT VECTOR MACHINE DENGAN ALGORITMA GENETIKA
Authors: Aziz Muhammad Abdul , Santoso Rukun , Warsito Budi
Published: February 2025

PT Pegadaian is a company that offers business capital loans to customers by providing collateral or a pawn system. Customers who cannot repay loans and are in arrears are considered non-potential. Non-potential customers are harm the company because it reduces capital and profits. Statistical methods are needed to predict potential. Predictions are made using the classification method, in this research is Support Vector Machine (SVM). However SVM has a weakness in determining optimal parameters, so optimization is carried out using genetic algorithms to help find optimal classification parameters. Genetic algorithms are used to find optimal solutions to problems by imitating observed processes. This study uses customer data and proof of pawn PT Pegadaian Kebumen on January 3rd 2022 – November 29th 2022. The support vector machine model is formed with a percentage of 80% for training data and 20% for test data. The conclusion in this study was that SVM-GA increased the accuracy obtained from 86,6% being 94,2%.
ANALISIS BACKTESTING UNTUK VALUE AT RISK METODE EKSPANSI CORNISH-FISHER DENGAN UJI KUPIEC
Authors: Rosyidah Hanifia , Maruddani Di Asih I , Safitri Diah
Published: February 2025

Returns and risks are important to pay attention before investing. Value at Risk (VaR) is a tool for measuring risk. VaR measures the worst-case loss at a certain level of confidence. Methodology and return distribution assumptions are important in estimating VaR. The classic VaR method can only be used for normally distributed returns. Cornish-Fisher Expansion (CFE) VaR doesn’t require distributional assumptions. VaR CFE takes into account skewness and kurtosis. The Covid-19 pandemic had a negative impact, but several companies still carrying out Initial Public Offerings (IPO). This research uses data on closing prices of PT Saraswanti Anugerah Makmur Tbk with returns that are not normally distributed. This company IPO during the Covid-19 pandemic. ECF VaR calculation with an initial investment of IDR. 1,000,000.00, a 95% confidence level results in a risk of Rp. 98,490.7 the next day. Backtesting uses the Kupiec Test to test the validity of the VaR model. The VaR obtained is valid for calculating the risk of SAMF because the probability of a violation occurring equal to the specified α. The number of violations according the Kupiec criteria table is between 16 and 36, namely 34 violations and the Likelihood Ratio value, namely LR=1,11735 < X^2(1;alpha) = 3,84 or Pvalue = 0,07095102 > alpha=0,05.
Navegando el horizonte digital: competencias para la transformación
Authors: García Rubiano Mónica
Published: February 2025

Con la transformación digital, el concepto de competencias se ha redefinido y ha dado lugar a las denominadas “competencias digitalizadas”, que van más allá del simple dominio de habilidades digitales básicas y abarcan la capacidad de adaptarse y prosperar en un entorno impulsado por la tecnología. La literatura enfatiza la importancia de cultivar una mentalidad digital que promueva la innovación, la agilidad y la adaptabilidad tanto a nivel individual como organizacional; así como el papel crucial de la comunicación electrónica (e-comunicación) y el liderazgo electrónico (e-liderazgo) en el desarrollo de competencias digitales en el lugar de trabajo. A partir de esto, las competencias digitalizadas representan una evolución de las habilidades tradicionales, pero adaptadas al mundo digital en constante cambio. Por otra parte, se evidencia que el avance tecnológico ha generado una creciente necesidad de competencias digitales en diversos ámbitos, como en la educación y el entorno empresarial, de manera que la alfabetización digital se ha vuelto esencial para el desarrollo personal y profesional y para promover la inclusión digital y cerrar la brecha digital. En el ámbito educativo, resalta la importancia de evaluar las competencias digitales de los docentes y promover la integración efectiva de la tecnología en la enseñanza; es en este sentido que el marco de competencias digitales para ciudadanos proporciona una guía integral para el desarrollo de competencias digitales en la sociedad actual, gracias a que hace énfasis en áreas clave como la información y alfabetización digital, la comunicación y colaboración, la creación de contenido digital, la seguridad y la resolución de problemas. Además, se reconoce la importancia de fomentar una cultura de innovación y aprendizaje continuo para impulsar el desarrollo de competencias digitales en el entorno laboral actual, así como de competencias digitalizadas, que resultan esenciales para la competitividad y el éxito empresarial, pues la digitalización está transformando la forma en que trabajamos y la distribución de tareas entre humanos y máquinas, lo cual requiere que los empleados desarrollen habilidades como la adaptabilidad, la autogestión y la capacidad de trabajar con tecnología avanzada. Finalmente, se destaca la importancia de desarrollar modelos de carrera flexibles que se adapten a las necesidades cambiantes de los empleados a lo largo de su vida profesional.
Employer branding: atracción y retención de talentos
Authors: Rodríguez Illera Katherine
Published: February 2025

En este capítulo se presenta una propuesta de employer branding (marca empleadora) como estrategia para la atracción y retención del talento humano en el competitivo mundo de la contratación. En un mercado laboral que cambia rápidamente, las empresas enfrentan grandes retos, como la rotación de personal, la escasez de profesionales altamente calificados y los cambios en las preferencias de la fuerza laboral, entre otros. Estos desafíos evidencian la necesidad de comprender los factores que influyen en la búsqueda de empleo y aceptación de ofertas laborales. Para abordar estos retos, se explora el concepto de employer branding como una estrategia clave en la atracción y retención de talentos, donde destacan tres factores esenciales para su desarrollo: la cultura organizacional, la comunicación y el posicionamiento. Posteriormente, se describe el proceso de evaluación, diagnóstico e intervención, resaltando las implicaciones tanto internas como externas para la gestión de la imagen del empleador, y se hace énfasis en las acciones que las organizaciones pueden desarrollar para identificar factores clave diferenciadores en su marca y transmitirlos de manera multidireccional a todos los niveles de la organización. Además, se destaca la forma en la que el employer branding contribuye al bienestar integral de las personas que participan directa o indirectamente en la organización, puesto que fomenta el aumento de la satisfacción y el compromiso de los colaboradores. Esto, a su vez, promueve la reputación en el mercado y el posicionamiento estratégico, factores cruciales para construir una marca empleadora sólida y atractiva, donde destaca la importancia del equilibrio entre la vida laboral y la vida personal, la percepción de la justicia organizacional y el trabajo sostenible. Finalmente, el capítulo concluye con una reflexión sobre el futuro del employer branding y la importancia de la diversidad e inclusión en la construcción de la marca empleadora. También, se analiza el papel de las redes sociales y plataformas digitales en la comunicación de la propuesta de valor a los públicos objetivos, destacando la necesidad de que las empresas se adapten continuamente a estos cambios para mantenerse competitivas y relevantes.
Roles de la gestión del talento humano: una visión desde la estrategia
Authors: Ferro Vásquez Jaime
Published: February 2025

Los procesos de administración de las personas que laboran en las organizaciones han cambiado bastante desde el siglo XX, más aún con el desarrollo de las nuevas Tecnologías de la Información y la Comunicación (TIC), y sobre todo después de los efectos de la pandemia por COVID-19, por su íntima relación con la transformación de las empresas en la actualidad. Se puede afirmar que las empresas vivían una realidad hasta el año 2019, vivieron otra durante los años 2020 y 2021 durante la pandemia, y viven una nueva desde el año 2022. Las formas de trabajar en las empresas se han transformado como consecuencia del uso de las tecnologías, pues se ha pasado de un trabajo prioritariamente en los espacios de la empresa, a un trabajo remoto, una forma de trabajo híbrido que incluye el trabajo en la oficina y el trabajo a distancia en variadas formas de presentación (en casa o en cualquier lugar). Adicional a esto, los espacios donde se trabaja se han modificado radicalmente, pues se ha pasado de trabajar en espacios de oficina cerrados, a ambientes físicos y escritorios abiertos o de uso libre, sin ubicación fija para los trabajadores, con el uso portátil de las tecnologías y sistemas de información en la nube. Esto, a su vez, ha ido transformando las relaciones sociales entre los empleados, las relaciones de autoridad en la interacción jefe-subalterno, y los procesos propios del diseño del trabajo. Todo lo anterior ha cambiado la forma en que se realiza la gestión del talento humano (GTH) en las organizaciones, sin embargo, se ha mantenido el dilema sobre el papel que juega esta dependencia en la organización. Teniendo esto en cuenta, el objetivo de este capítulo es presentar una alternativa para que el área de GTH asuma un papel estratégico acorde con los objetivos de las organizaciones. En este sentido, se abordan los conceptos de cambio organizacional, cultura organizacional y liderazgo transformacional como factores estratégicos en la empresa, y se presenta y desarrolla la propuesta de Dave Ulrich (2008) sobre el modelo de múltiples roles de la GTH en las organizaciones, haciendo énfasis en el rol estratégico. Así, se tratan inicialmente algunos conceptos sobre estrategia y planeación estratégica desde la óptica del factor humano, para después desarrollar el modelo de múltiples roles, en sus cuatro componentes, y se especifican las acciones propuestas con el fin de alinear la GTH con la estrategia organizacional. Claramente, no se deja de lado la influencia de las transformaciones tecnológicas en términos de big data, inteligencia artificial y tecnología predictiva, tan relevantes para el momento presente. Por último, se revisan aspectos de la vigencia del modelo y se concluye con los retos que las áreas de GTH deben asumir a partir de dichas transformaciones.
La microformación: una práctica esencial para adquirir nuevas competencias laborales
Authors: Hernández Rincón Sandra Patricia
Published: February 2025

La microformación se ha convertido en una tendencia fundamental en el ámbito de la formación empresarial, gracias a que ofrece una respuesta efectiva a los desafíos de un mercado laboral en constante evolución. Al proporcionar módulos de aprendizaje cortos y altamente accesibles, la microformación permite a las organizaciones fomentar una cultura de aprendizaje continuo entre sus empleados, así como una adaptación rápida a los cambios del entorno, en tanto que consiste en la presentación de contenidos, procesos y métodos en línea, accesibles con un solo clic, y con una duración de entre 3 y 5 minutos, diseñados con el fin de que los empleados adquieran conocimientos y habilidades de forma gradual y efectiva. Al aprovechar técnicas como el espaciado y la repetición, la microformación favorece la retención a largo plazo, lo cual le permite a los trabajadores afianzar conocimientos poco a poco y construir comportamientos eficaces, pero sin sobrecargar sus horarios. Entre los beneficios que tiene la microformación se pueden encontrar que, para las empresas, mejora la productividad, facilita la adaptación a nuevas tecnologías y procesos, incrementa la retención del talento y fortalece la marca empleadora; mientras que, para los empleados, permite un desarrollo profesional continuo, fomenta la autonomía y el empoderamiento, y se adapta al ritmo de vida laboral. De hecho, se ha encontrado que ofrecer experiencias de aprendizaje personalizadas, flexibles y eficientes aumenta la satisfacción de los empleados, mejora el clima laboral y contribuye a construir organizaciones más ágiles y competitivas. En conclusión, esta modalidad de formación revoluciona la forma en que las organizaciones abordan la capacitación de sus empleados, pues a través de módulos cortos y personalizados, los trabajadores pueden adquirir nuevas habilidades, reforzar conocimientos existentes y mantenerse actualizados en su campo, gracias a contenidos concisos y prácticos que les permiten adquirir habilidades de manera efectiva en poco tiempo y sin interrumpir sus actividades diarias. Además, la variedad de formatos disponibles, como videos interactivos, tutoriales y simulaciones, hace que el aprendizaje sea más atractivo y memorable.
To solve the dilemma of modern medical ethics review with the wisdom of traditional Chinese philosophy
Authors: Ai Jing , Yu Xiao , He Manhui , You Zeshan , Li Zaiyi
Published: February 2025

Modern medical technology is advancing at an unstoppable pace. The scope of medical research has expanded from organs and tissues to the cellular and genetic levels, touching the essence of human life. The modern medical ethics review systems and theories, predominantly rooted in Western frameworks, have not been fully integrated with Chinese cultural contexts, leading to challenges in resolving increasingly complex ethical disputes. By reflecting on the limitations of modern medical ethics review systems and exploring the potential of integrating traditional Chinese philosophy with Western theories, this article aims to develop a framework tailored to Chinese cultural and academic contexts. This approach includes integrating conventional Chinese philosophy into the academic foundation of medical ethics, recruiting ethics committee members with expertise in Chinese culture and philosophy.
Evaluating the research parameters available on the Sysmex® XN-series hematology analyzers as markers of dysplasia in peripheral blood
Authors: Aguadero Vicente , López María , Ruíz Míriam , Regidor Diana , Celma Gemma
Published: February 2025

Objectives

Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by peripheral blood cytopenias, cellular dysplasia and risk for progression into acute leukemia. Recent studies reveal that some research parameters available on Sysmex XN-1000® hematology analyzers, including immature platelet fraction (IPF), Neutrophil Granularity Index (Neu-GI), or platelet distribution width (PDW), show a relationship with dysplasia in peripheral blood. The objective of this study was to examine the association between classic and research blood count parameters and the presence of dysplasia. The secondary objective was to develop a multivariate model that allows the prediction of dysplasia with high probability.

Methods

Seventy-five patients older than 60 years with anemia, leukopenia or thrombocytopenia, without vitamin B12 and folate deficiency or hematological diseases underwent testing with the Sysmex XN-1000 analyzer.

Results

Dysplasia was confirmed in 32 % of patients, with significant differences in Neu-GI, PDW and IPF count between the groups of patients with and without dysplasia. Neu-GI was the parameter with the highest predictive value (AUC=0.98), with such value not increasing significantly after the addition of PDW or PIF. A Neu-GI value≤146ch predicts dysplasia with a positive predictive value=90 %.

Conclusions

Neu-GI is the parameter most strongly associated with dysplasia. A Neu-GI value≤146ch indicates a high probability of dysplasia and supports indication for a blood smear review. Additionally, values>152ch indicate a low probability of dysplasia.
Green approach for the synthesis of zinc oxide nanoparticles from methanolic stem extract of Andrographis paniculata and evaluation of antidiabetic activity: In silico GSK-3β analysis
Authors: Kumar Gopal Nithesh , Ali Mohammad , Raghunathanaidu Bharathi Doddla , Ahmed Syed Sagheer , Komalkumar Chandan , Ananth Gowda KM Doddi Hanumaiah , Prajwal Chamanahalli Balaraju , Shakeel Faiyaz
Published: February 2025

In this study, zinc oxide nanoparticles (ZnO-NPs) were biosynthesized from methanolic stem extract of Andrographis paniculata (MEAP) and characterized physicochemically. ZnO-NPs were evaluated biologically for anti-diabetic and anti-nephropathy activities. A diabetic rat model generated by streptozotocin was used to test the anti-diabetic properties of ZnO-NPs. In diabetic rats, oral doses of MEAP and ZnO-NPs generated from MEAP were given once daily for 30 days at 100, 200, 300, 400, 600, and 1,200 mg·kg−1, respectively. Metformin, a common antidiabetic drug, was utilized as a control at a dosage of 250 mg·kg−1. The NPs mediated by MEAP were homogenous, stable, spherical, and tiny. MEAP-derived ZnO-NPs prevented weight loss while significantly (p < 0.05) lowering blood glucose levels in comparison to MEAP and, to a lesser extent, metformin. Furthermore, MEAP-mediated ZnO-NPs were found to have favorable effects on the lipid profile and diabetic nephropathy. The histopathological evaluation demonstrated the safety, non-toxicity, and biocompatibility of synthesized ZnO-NPs produced from MEAP. The hypoglycemic response to MEAP-derived ZnO-NPs was greater at 400 mg·kg−1·day−1 than it was at 200 and 100 mg·kg−1·day−1. Therefore, ZnO-NPs biosynthesized from MEAP exhibit more anti-diabetic and anti-nephropathy action than MEAP in this first experimental setting reported.
Associations of serum levels of cGAMP in the context of COVID-19 infection, atherosclerosis, sterile inflammation, and functional endothelial biomarkers in patients with coronary heart disease and healthy volunteers
Authors: Gumanova Nadezhda G. , Bogdanova Natalya L. , Gorshkov Alexander Yu.
Published: February 2025

Objectives

The present study evaluated the relationships of the serum levels of the cyclic dinucleotide 2′3′-cyclic GMP-AMP (cGAMP) marker of activation of pattern-recognition receptors with immunoglobulin G antibodies against severe acute respiratory syndrome-linked coronavirus (IgG-SARS)-positive status and endothelial dysfunction.

Methods

Selected groups from two cohorts (cohort 1 of 307 healthy volunteers and cohort 2 of 218 coronary heart disease [CHD] patients). COVID-19 infection was confirmed by detection of IgG-SARS against SARS-CoV-2 S1 protein receptor-binding domain. Cohort 1 was examined for systematic coronary risk evaluation by European Society of Cardiology (SCORE) starting from 2019 before the onset of the COVID-19 pandemic. Cohort 2 was processed starting from 2017 (three years prior to the COVID-19 pandemic) in a hospital setting to undergo coronary angiography to assess coronary lesions as Gensini score. The levels of cGAMP and endothelial markers (nitrate and nitrite combined as NOx and endothelin-1) were assessed in the serum to evaluate the associations with IgG-SARS status, SCORE, and extent of coronary lesions by correlation and receiver operating characteristic analyses.

Results

Serum cGAMP did not discriminate between SARS-positive and SARS-negative healthy subject of cohort 1. Moreover, the level of cGAMP was not associated with endothelial biomarkers in healthy subjects. However, Serum cGAMP was associated with atherosclerosis, with area under the curve 0.69 (95 % CI 0.587–0.806; p=0.001), and with endothelial markers in cohort 2.

Conclusions

Low cGAMP was associated with atherosclerosis in CHD patients, suggesting that cGAMP is a new biomarker in the context of sterile inflammation.
DsubCox: a fast subsampling algorithm for Cox model with distributed and massive survival data
Authors: Zhang Haixiang , Li Yang , Wang HaiYing
Published: February 2025

To ensure privacy protection and alleviate computational burden, we propose a fast subsmaling procedure for the Cox model with massive survival datasets from multi-centered, decentralized sources. The proposed estimator is computed based on optimal subsampling probabilities that we derived and enables transmission of subsample-based summary level statistics between different storage sites with only one round of communication. For inference, the asymptotic properties of the proposed estimator were rigorously established. An extensive simulation study demonstrated that the proposed approach is effective. The methodology was applied to analyze a large dataset from the U.S. airlines.
On 2-stage martensitic transformation behavior in aged Ti50.5Ni33.5Cu11.5Pd4.5 alloys with near-zero thermal hysteresis
Authors: Li Hang , Chen Lili , Guan Xiaoguang , Cai Yang , Meng Xianglong , Cai Wei
Published: February 2025

The microstructures and martensitic transformation of a Ti-rich Ti50.5Ni33.5Cu11.5Pd4.5 alloy aged at 500 °C for durations ranging from 15 min to 25 h were systematically investigated. With increasing aging time, the precipitates exhibit continuous growth; however, their quantity initially increases and subsequently decreases. The morphology of the precipitates evolves from granular to lamellar forms. Post-aging treatment, the transformation sequence transitions from a one-stage (B2–B19) to a two-stage process (B21–B191 and B22–B192) due to the precipitation of Ti2Cu-type particles, maintaining near-zero hysteresis. The two-stage martensitic transformation originates from the combined effects of stress distribution heterogeneities and variations in Ni content induced by aging precipitation.
Microstructure, XRD characteristics and tribological behavior of SiC–graphite reinforced Cu-matrix hybrid composites
Authors: Sharma Avinash , Porwal Rajesh K.R.
Published: February 2025

This study’s main goal is to investigate how the properties of pure copper are impacted by the addition of silicon carbide–graphite reinforcement. Here in this research a powder metallurgy procedure is used to make copper matrix composites with different amounts of silicon carbide–graphite reinforcement (2 %, 5 %, 8 %, and 10 %) by weight. The microstructure, phases present, wear analysis, and X-ray diffraction analysis were all thoroughly examined, while scanning electron microscopy was used for imaging the microstructure of materials. The absence of any intermediate phases between the reinforcing materials and the copper matrix, according to X-ray diffraction data, suggests a strong interfacial interaction between them. A microstructural analysis of the copper matrix indicated a consistent dispersion of silicon carbide–graphite. The amount of reinforcement employed was found to have an impact on the wear characteristics of these copper matrix composites. Notably, the softness of graphite caused the hardness to drop when it was added. The 5 % reinforcement composite material outperformed the other evaluated composite materials in terms of wear rate, which was calculated in term of specific wear rate by using a pin-on-disc testing machine. This implies that this specific composite could be useful for tribological applications.
Linguistic aspects of the scientific research article in 1715 with particular reference to two astronomy articles
Authors: Banks David
Published: February 2025

Astronomy is the most important subject treated in the Philosophical Transactions and the Mémoires de l’Académie Royal in 1715. Articles by Halley and Maraldi have been selected for analysis. The process type profiles of the two articles are very similar. The object of study is the most important type of theme in both, but the proportion of themes of this type in Maraldi’s text is much greater than that in Halley’s. Surprisingly, temporal themes play a significant role in Halley’s text. Also surprising is the fact that, in Halley’s text, adjunct themes are more frequent than subject themes. Nominalized processes tend to be material rather than mental, but the difference is greater in Halley’s text than in Maraldi’s. First person pronoun subjects tend to occur with mental process verbs, but whereas in Halley’s text material processes also play a part, there are hardly any in Maraldi’s text. These linguistic differences between the two texts can be explained in terms of their differing stances, that of Halley being Baconian and hence empirical, that of Maraldi being Cartesian and hence deductive.
Spatiotemporal optical vortex reconnections of loop vortices
Authors: Adams Jordan , Chong Andy
Published: February 2025

Reconnections of spatiotemporal optical vortices have been shown to occur between line vortices. Here, we show that reconnections also occur between spatiotemporal loop vortices in optical waves. As optical loop vortices propagate in a media with spatial diffraction and material group velocity dispersion, unique reconnections occur. The birth and death of loops can occur, with certain loop vortices emerging from or collapsing to a single point while interacting with others. As certain parameters are varied in the model, complex arrangements of loops form in space-time from simple initial fields.
Assessment of nutrition status of pineapple plants during ratoon season using diagnosis and recommendation integrated system
Authors: Anh Nguyen Huynh Minh , Hiep Phan Chan , Ngan Nguyen Thanh , Tho Le Thi Ngoc , Trong Nguyen Duc , Thuan Vo Minh , Thien Tran Thi Ngoc , Quang Le Thanh , Khuong Nguyen Quoc
Published: February 2025

The use of chemical fertilizer based on farmers' experience has led to fertilizer over-application in Hau Giang province, leading to increased production costs and severe environmental pollution. Therefore, it is important to assess crop nutrition status and make nutrient recommendations. Therein, the diagnosis and recommendation integrated system (DRIS) is a well-known approach to evaluating the nutrition status of crops. The current study aimed (i) to evaluate the sensitivity of established DRIS norms set for ratoon pineapple and (ii) to appraise the nutrition status of the plants in different regions of Hau Giang province, Vietnam. An omission plot experiment was conducted with a fully fertilized treatment and treatments omitting each nutrient of nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), and magnesium (Mg) at leaves +1, +3, +7, +14, +15, +18, +20, +22, and +24. In the results, at leaf +1 and leaf +7, the DRIS indices of the groups omitting each of P, K, Ca, and Mg nutrients were lower than those of the NPKCaMg group, i.e., the leaves +1 and +7 had greater reliabilities. Based on leaf +1, the requirement order for nutrients of the ratoon pineapple was Cu > Ca > K > Zn > P > N > Fe > Mn. The newly established DRIS can be provided to the local agriculture managers to recommend the farmers to improve their profits and lower the use of chemical fertilizers for ratoon pineapple. Moreover, the results of this study will be a valuable reference for the establishment of DRIS in the world.
Commodifying Bodies and Regulating Wombs: Legacies of Black Reproductive Coercion in America
Authors: Habib Serena
Published: February 2025

...
VTA µ-opioidergic neurons facilitate low sociability in protracted opioid abstinence
Authors: Jo Adrienne Y. , Xie Yihan , Wooldridge Lisa M. , Rogers Sophie A. , Kimmey Blake A. , Rodrigues Amrith , Sandoval Ortega Raquel Adaia , Creasy Kate Townsend , Beier Kevin T. , Blendy Julie A. , Corder Gregory
Published: February 2025

Opioids initiate dynamic maladaptation in brain reward and affect circuits that occur throughout chronic exposure and withdrawal that persist beyond cessation. Protracted abstinence is characterized by negative affective behaviors such as heightened anxiety, irritability, dysphoria, and anhedonia, which pose a significant risk factor for relapse. While the ventral tegmental area (VTA) and mu-opioid receptors (MORs) are critical for opioid reinforcement, the specific contributions of VTAMORneurons in mediating protracted abstinence-induced negative affect is not fully understood. In our study, we elucidate the role of VTAMORneurons in mediating negative affect and altered brain-wide neuronal activities following forced opioid exposure and abstinence in male and female mice. Utilizing a chronic oral morphine administration model, we observe increased social deficit, anxiety-related, and despair-like behaviors during protracted forced abstinence. VTAMORneurons show heightened neuronal FOS activation at the onset of withdrawal and connect to an array of brain regions that mediate reward and affective processes. Viral re-expression of MORs selectively within the VTA of MOR knockout mice demonstrates that the disrupted social interaction observed during protracted abstinence is facilitated by this neural population, without affecting other protracted abstinence behaviors. Lastly, VTAMORscontribute to heightened neuronal FOS activation in the anterior cingulate cortex (ACC) in response to an acute morphine challenge, suggesting their unique role in modulating ACC-specific neuronal activity. These findings identify VTAMORneurons as critical modulators of low sociability during protracted abstinence and highlight their potential as a mechanistic target to alleviate negative affective behaviors associated with opioid abstinence.

Significance statementThe compelling urge for relief from negative affective states during long-term opioid abstinence presents a crucial challenge for maintaining abstinence. The ventral tegmental area (VTA) and its mu-opioid receptor-expressing (VTAMOR) neurons represent a critical target of opioidergic action that underlie dependence and abstinence. Chronic activation of VTAMORneurons during opioid exposure induces maladaptations within these neurons and their structurally connected circuitries, which alter reward processing and contribute to negative affect. Using an oral morphine drinking paradigm to induce dependence, we demonstrate that withdrawal engages VTAMORneurons and identify this neuronal population as key mediators of opioid abstinence-induced social deficits. These findings hold promise to inform development of targeted therapies aimed at alleviating negative affective states associated with protracted opioid abstinence.