bluuebunny/crossref_metadata_2025 huggingface dataset:
Diseño de un plan de administración y marketing para la creación de una marca deportiva orientada a las actividades turísticas
Authors: Gavilanes-Franco Marina de Jesús , Viñachi-López Hector Leonardo , Quiñonez-Mendoza Carolina , Intriago-Mera Rafael Aníbal , Masache-Heredia Mauricio Alberto , Sampietro-Saquicela José Luis
Published: May 2023

Detrás del éxito de un plan de marketing se encuentra un conjunto de esfuerzos y estudio por parte de un gran equipo de trabajo. Se debe hacer un extenso análisis de la organización, su micro y macro entorno para poder ver sus oportunidades, debilidades, amenazas y fortalezas y en base a ellas hacer un plan de acción.  Dentro de los principales objetivos de un plan de marketing, se encuentra la utilización de recursos para atraer y fidelizar clientes a la marca. Para lograrlo, se deben establecer estrategias desde las 4P’s del mercado: Precio, Producto, Promoción y Punto de venta. Una vez establecidas las estrategias se debe idear un plan de acción dentro de un tiempo establecido. La marca La Sportiva es conocida por la exclusividad, calidad de sus productos, al igual que por siempre satisfacer las necesidades y exigencias de sus clientes. La empresa se caracteriza por ser familiar, sin embargo, cuenta con toda la tecnología y recursos para la innovación. Siendo una marca que se ha caracterizado siempre por buscar cumplir y satisfacer las exigencias de sus clientes, se busca seguir con la tradición tomando un enfoque por la preocupación su salud. El mercado potencial de La Sportiva está conformado por personas atléticas que principalmente, disfrutan de actividades al aire libre. La exposición al sol está comprobada que causa efectos dañinos y perjudiciales sobre la piel y es por esto que se plantea en el siguiente trabajo, una línea de ropa deportiva que brinde la protección necesaria contra los rayos UV.
Planificación curricular en el ámbito de la cultura física, recreación y deporte para el desarrollo de estilos de vida saludables
Authors: Garcia-Caicedo Vilma Viviana , Rivas-Rosero Juan Guillermo
Published: May 2023

El objetivo de la presente investigación fue analizar el empleo de una planificación curricular en el ámbito de la cultura física, recreación y deporte para el desarrollo de estilos de vida saludables. La metodología será de carácter no experimental, transversal, el nivel de la investigación será de tipo teórica- descriptiva y por el nivel de análisis de la información será mixta cuantitativa-cualitativa. El método considerado fue el deductivo; la población quedó conformada por 10 docentes. La técnica e instrumento de recolección de datos fue la encuesta y el instrumento el cuestionario. Se encontró que los docentes realizan una planificación curricular correspondiente a su área de conocimiento (80%). Dentro de ella, el 70% incluyen estrategias didácticas para favorecer la adquisición de estilos de vida saludable y aquellas que favorezcan el interés por la salud (80%); el 70% considera que el desarrollo de eta planificación incide en los cambios de actitud en los estudiantes. Sin embargo, no promueven la participación activa de los estudiantes en acciones que favorezcan estas conductas. Estos resultados permiten reflexionar en torno a la importancia de la toma de decisiones curriculares sobre lo que deben enseñar y qué deben aprender los alumnos, en virtud de que se están tomando también decisiones sobre qué tipo de persona y qué tipo de sociedad se quiere contribuir a conformar con la educación que se imparte, y la inclusión de una planificación curricular que favorezca el cultivo de la salud, es crucial para el país.
Estrés laboral en actividades de teletrabajo por Covid-19, en docentes de la Unidad Educativa Particular Evangélica Luz y Libertad de la ciudad de Esmeraldas
Authors: Quiñónez-Portocarrero Diana Katherine
Published: May 2023

Debido a la pandemia del Covid19 el Ministerio de Educación en  Ecuador determinó  que el  personal administrativo y docentes de las instituciones educativas debían realizar sus labores mediante la modalidad de teletrabajo, razón por la cual los docentes tuvieron que adaptar sus hogares con gran rapidez para realizar las actividades en forma virtual convirtiéndose  el uso de las tecnologías y  manejo de las plataformas educativas en un factor  de estrés laboral  debido a que la mayoría de docentes no estaban adaptados a la era tecnológica. La presente investigación fue realizada con el propósito de identificar las condiciones laborales en las cuales los docentes de la Unidad Educativa Particular Evangélica Luz y Libertad se encontraban realizando las actividades de teletrabajo debido al Covid19 y determinar si estaban experimentando niveles de estrés. La metodología empleada fue de tipo descriptiva-transversal con un enfoque cuantitativo de alcance descriptivo. La población estuvo conformada por 20 docentes a quienes se les aplicó el Cuestionario de Estrés Laboral de Karasek y la Encuesta Estresores Laborales Teletrabajo/Covid 19. Los resultados evidenciaron los siguientes estresores en las actividades de teletrabajo: uso de celular para dictar clases, no contar con un computador, compartir su equipo tecnológico con familiares, aumento de la carga laboral, inadecuados lugares para realizar el teletrabajo, extender el horario de trabajo para concluir las labores educativas, generando mayor cansancio físico y mental que se han traducido en depresión, agobio, falta de concentración y preocupaciones. Estas condiciones negativas de teletrabajo debido al Covid19, han generado que el 85% de los docentes evaluados experimentan un nivel de estrés moderadamente alto, afectando su salud y desempeño laboral. Finalmente se consideró necesario gestionar adecuadamente un plan de estrategias preventivas que permitan mejorar las condiciones de los docentes de la Unidad Educativa Particular Luz y Libertad, enfocado en estrategias para: Tiempo y organización del trabajo, Gestión del desempeño, Digitalización y Seguridad y salud en el trabajo.
La planificación de estrategias didácticas en el área de la cultura física, recreación y deporte para el desarrollo de competencias para el mantenimiento óptimo del estado físico y emocional del estudiante
Authors: Rivas-Rosero Juan Guillermo , Garcia-Caicedo Vilma Viviana
Published: May 2023

Esta investigación, presenta como objetivo general un análisis sobre la planificación de estrategias didácticas en el área de la cultura física, recreación y deporte para el desarrollo de competencias para el mantenimiento óptimo del estado físico y emocional del estudiante en una Unidad Educativa del nivel de secundaria de Guayaquil, Ecuador. La metodología se concibe como de enfoque cuantitativo con un diseño de campo; no experimental, fundamentada en una investigación documental y bibliográfica. La muestra correspondiente quedó compuesta por doce (12) miembros del cuerpo docente del área de la cultura física, recreación y deporte. Para la recolección de la información respectiva se utilizó un cuestionario, con cuatro opciones de respuesta (siempre, casi siempre, pocas veces, nunca). En resumen, una conclusión sobresaliente de este estudio es la necesidad de adoptar en la planificación didáctica el desarrollo de contenidos orientados al fomento de competencias ligadas tanto a la actividad física como a la educación emocional del estudiante que perduren en el tiempo como expresión de vida saludable.
Pemberian Makanan Pendamping ASI (MP-ASI) dengan Kejadian Diare pada Bayi Usia 0-12 Bulan
Authors: Kariani Ni Ketut , Indriningsi Sri
Published: May 2023

Background: Nowdays, Diarrhea still become main caused of sickness and mortality even toward babies and children. One of predisposition factor of dirrhea is extra breast feeding administered before 6 months in age. Aims: The aims of this research to obtain the correlation of extra breast feeding administered with diarrhea toward babies 0 12 months old in Lebiti Public Health Center (PHC), Togean Subdistrict. Methods: This is quantitative research with cross sectional approached. The total population about 214 of the women who have babies with 0 – 12 months old and got diarrhea disease experiences within last 2 years. The sampling only 61 women that taken by accidental sampling technique. The tools used by questioniarre and data analysed by chi-square test. Results: The result shown that have orrelation of extra breast feeding administered with diarrhea toward babies 0 12 months old in Lebiti Public Health Center (PHC), Togean Subdistrict of Tjo Una Una Regency with pvalue = 0,002. Conclusion: mother who give MP-ASI to babies regardless of age, frequency, portion, type, and method giving the right MP-ASI.
EDUCATIONAL DIPLOMACY AS SOFT POWER: JEAN MONNET SCHOLARSHIP PROGRAM
Authors: TERZİOĞLU Elifnur
Published: May 2023

In the changing world system, various transformations have taken place in the field of communication as well as in other fields. Countries have decided to carry out their bilateral cooperation through public diplomacy elements such as cultural, social and educational, instead of the classical diplomacy understanding in which hard power elements such as military and economy are used, and in this direction, they have started to carry out moderate communication activities for foreign public opinion. Soft power elements, one of the basic components of public diplomacy, emerge as a very important concept in order to establish more moderate relations on behalf of countries after hard power. This soft power element, which we can call education diplomacy, enables countries to establish good relations with each other in the international arena and to provide long-term benefits. The study aims to analyze the role of the Jean Monnet Scholarship Program on public diplomacy and education diplomacy by using qualitative and quantitative content analysis. In the selection of the data, Turkey-based 2007-2008 and 2021-2022 academic periods were considered and document analysis method was used in the data collection process within the scope of the research. In the quantitative content analysis carried out on the identified sample, it was found that the number of students benefiting from the scholarship program was 1476, 811 women and 665 men. Considering that this number is only within the scope of the said academic periods, it has been concluded that it is quite significant in terms of education diplomacy.
Analisis dan Perbaikan Proses Bisnis dalam Perspektif Sistem Informasi
Authors: Tawar  , Pangestu Pradana Yoga
Published: May 2023

Penelitian ini bertujuan untuk menganalisis proses bisnis pada pusat pengembangan karir di perguruan tinggi. Penelitian ini menggunakan pendekatan Business Process Modeling Notation (BPMN) dan metode kualitatif-kualitatif dalam analisis proses bisnis. Tahapan penelitian meliputi tinjauan literatur, pengumpulan data melalui wawancara dan observasi, identifikasi proses bisnis, pemodelan proses bisnis, simulasi proses bisnis, serta kesimpulan dan rekomendasi. Hasil penelitian menunjukkan bahwa proses bisnis pada pusat pengembangan karir memerlukan perbaikan pada beberapa aspek. Pemetaan proses bisnis menunjukkan terdapat beberapa proses bisnis utama dan pendukung yang dapat dioptimalkan. Berdasarkan pemodelan proses bisnis yang sudah berjalan (as-is), peneliti menganalisis dan memperbaiki proses bisnis dengan menggunakan salah satu alat penyederhanaan dari Business Process Improvement (BPI). Selanjutnya, berdasarkan hasil analisis dan evaluasi, peneliti merekomendasikan model proses bisnis yang baru (to-be) untuk meningkatkan efisiensi dan efektivitas proses bisnis pada pusat pengembangan karir. Dampak dari penelitian ini adalah memberikan kontribusi bagi pengembangan proses bisnis pada pusat pengembangan karir. Model proses bisnis yang direkomendasikan dapat membantu dalam meningkatkan kualitas layanan dan efisiensi proses bisnis. Selain itu, metode dan pendekatan yang digunakan dalam penelitian ini juga dapat menjadi referensi bagi peneliti lain yang tertarik untuk melakukan penelitian serupa.
CASE REPORTS: Presumed topiramate-induced retinopathy in a 58-year-old woman
Authors: Cheng Zhihang , Purcell William , Ghadiri Nima , Tan Shi Zhuan , Madhusudhan Savita
Published: May 2023

We present a case of presumed topiramate-induced retinopathy in a 58-year-old woman who presented with progressive, bilateral visual loss following a 3- to 4-year history of oral topiramate intake for migraine. She reported difficulty with light adaptation, hemeralopia, and color desaturation. Her best-corrected visual acuity was 1/60 (20/1200) in the right eye and 6/18 (20/60) in the left eye, and she performed poorly on Ishihara color plate testing. Anterior segment examination was normal; dilated funduscopy showed mild macular pigmentary changes. Optical coherence tomography revealed subtle thinning and reduced reflectivity of the subfoveal ellipsoid zone and interdigitation zone bilaterally, associated with increased foveal autofluorescence. Humphrey visual field 24-2 revealed central defects. Electrodiagnostic testing showed a reduced and delayed b-wave and a normal a-wave on photopic full-field electroretinogram (ERG), with normal scotopic responses; multifocal ERG revealed reduced responses in the inner 10° in both eyes. She underwent extensive investigations including whole-body computed tomography and positron emission tomography scan, magnetic resonance imaging of the brain, uveitis screening, retinal autoantibody testing, and genetic testing on the retinal dystrophy panel to rule-out other causes for her presentation, all of which were normal or negative.
Papel do planejamento familiar na atenção primária à saúde
Authors: Rios Giovana Barroso de Melo , Costa Lourrany Borges , Rodrigues Marília Teixeira , Rodrigues Iana Castelo , Paula Fernanda de Oliveira , Forte Morgana Pordeus do Nascimento , Neri Carmem Rita Sampaio de Sousa
Published: May 2023

Introdução: A assistência ao planejamento familiar no âmbito da atenção primária compreende um importante conjunto de ações capazes de garantir o direito à saúde reprodutiva aos usuários do Sistema Único de Saúde brasileiro. Entretanto vários obstáculos impedem sua implementação plena, fazendo com que muitos usuários não tenham acesso a esse serviço. Objetivo: Analisar o papel do planejamento familiar na construção da parentalidade sob a ótica de usuários de serviços de atenção primária à saúde em Fortaleza (CE). Métodos: Estudo transversal de métodos mistos, com triangulação concomitante de dados, de acordo com Creswell e Clack. Para a fase quantitativa, selecionaram-se 60 pessoas em exercício da parentalidade para responder a um questionário estruturado, das quais 12 participaram da fase qualitativa através de entrevistas semiestruturadas. Resultados: Em relação às respostas ao questionário, a maioria dos participantes teve o primeiro filho entre 17 e 20 anos, atualmente possui dois filhos e permanece com a mesma parceria da época do primogênito. As entrevistas evidenciaram o desconhecimento sobre o planejamento familiar, atribuído a escassez da assistência, falta de acolhimento pelos profissionais de saúde, ineficiência de políticas e desinteresse da população. A triangulação de métodos evidenciou complementação e corroboração entre os dados quantitativos e qualitativos. A integração de dados permitiu observar um apelo à corresponsabilidade da população em relação ao planejamento familiar, além da necessidade de mais treinamento e sensibilização dos profissionais de saúde quanto ao tema. Conclusões: É necessário avançar na abordagem do planejamento familiar no contexto da atenção primária à saúde para que este possa se tornar de fato um espaço de cuidado, troca e desenvolvimento da parentalidade efetiva e afetiva.
Bir Eğitim Araştırma Hastanesinde Çalışan Asistan Hekimlerin Alerji Yönetimi
Authors: SARI UNAT Sevtap , GÖK BALCI Umut
Published: May 2023

Giriş: Alerji, vücudun savunma sisteminin diğer sağlıklı kişilerin reaksiyon vermediği maddelere aşırı reaksiyon vermesidir. Alerjik hastalıklar ve reaksiyonlarla her sahada sık karşılaşan hekimlerin hastaları değerlendirmesi, acil ilk müdahaleyi yapabilmesi, gerekli durumlarda ileri tetkik ve tedavi amacıyla hastaları alerji ve immünoloji uzmanına yönlendirebilmesi büyük önem taşımaktadır. Bu çalışmada asistan hekimlerin alerjik hastalıkların tanı, tedavi ve izlemi konusunda genel yaklaşımlarının ve bilgi düzeylerinin ölçülmesi amaçlandı.
Gereç ve Yöntem: Bir eğitim ve araştırma hastanesinde çalışan, farklı branşlardan 260 asistan hekime, araştırmacılar tarafından hazırlanan anket, yüz yüze görüşme tekniği ile uygulandı. Veriler SPSS.21 paket programı ile analiz edildi. Bulgular: Çalışmamızda, hekimlerin alerjik hastalıklar ve yönetimine yönelik bilgi sorularına verdikleri yanıtlar değerlendirildiğinde 260 hekimden tam puan alan olmadığı görüldü. Bilgi soruları toplam 10 puan üzerinden değerlendirildi. En yüksek puan olarak 8 puana ulaşan asistan hekim sayısının 33 olduğu görüldü. Sonuç: Tüm branşlardaki hekimlerin alerji yönetimi ile ilgili tam ve donanımlı olmasını sağlamak için bu konularda meslek içi eğitimin artırılmasının yararlı olacağı çalışmamızın ana sonucudur.
Urgensi Penegakan Hukum E-Commerce di Indonesia: Sebuah Tinjauan Yuridis
Authors: Dianta Dedon
Published: May 2023

Semakin bergejolaknya dunia pada era globalisasi ini atas hadirnya perkembangan ilmu pengetahuan dan teknologi yang membuat dunia sangatlah modern. Hadirnya e-commerce merupakan salah satu dampak dari berkembangnya teknologi dalam dimensi perdagangan. Hadirnya e-commerce ini juga memperluas perdagangan dari yang semula hanya bersistem tatap muka, sekarang menjadi online. Tentunya juga dengan hadirnya e-commerce ini, mengharuskan adanya hukum yang mengatur tentangnya, sebagai kepastian hukum terhadap sistematika e-commerce dengan berbagai macam kelebihan dan kekurangannya. Penelitian ini bertujuan meninjau dan mengetahui terkait dengan hukum e-commerce yang ada di Indonesia beserta dengan regulasi perijinan dalam pendirian usaha e-commerce. Hadirnya penelitian ini, penulis berharap pembaca dapat lebih paham mengenai keadaan hukum positif di Indonesia mengenai e-commerce.
Peran Pemimpin dalam Pencapaian Tujuan Organisasi: Studi Pada DPD Pemuda Panca Marga Provinsi Sulawesi Tenggara
Authors: Hasina Hado , Satyadharma Maudhy
Published: May 2023

Penelitian ini bertujuan untuk melihat mendeksripsikan dan menganalisis (1) gambaran kegiatan PPM Provinsi Sulawesi Tenggara dan, (2) peran pemimpin dalam menunjang terwujudnya tujuan PPM Sultra. Jenis Penelitian ini adalah penelitian deskriptif dengan pendekatan kualitatif. Penelitian dengan metode deskripsi kualitatif ini digunakan agar peneliti bisa menjelaskan lebih mendalam dan menyeluruh mengenai gambaran kasus yang terjadi di lapangan. Penelitian telah dilaksanakan di Kota Kendari pada bulan Oktober - Desember 2022. Hasil penelitian menyimpulkan bahwa (1) Pemuda Panca Marga (PPM) Provinsi Sulawesi Tenggara sudah melaksanakan kegiatan yang dilandaskan pada peran yang harus dimainkan yaitu a)menjaga, melestarikan dan mewariskan jiwa semangat 1945, b) berperan serta secara aktif dalam pembangunan nasional dan c) berperan aktif dalam sistem pertahanan keamanan rakyat semesta (sishankamrata) terkait upaya pembelaan negara, (2) Pemimpin memainkan peranan yang penting dalam organisasi PPM Provinsi Sulawesi Tenggara untuk dapat menjalankan segala peran dan keberhasilan kegiatan yang direncanakan. Hal itu terlihat dari dipenuhinya berbagai ciri pemimpin yang efektif yaitu a)bersifat dan bersikap adil, b) memberi sugesti, c) mendukung tujuan, d)katalisator, e) menciptakan rasa aman, f) sebagai wakil organisasi, g) sumber inspirasi, dan h) bersikap menghargai.
Pengaruh Kompensasi terhadap Kinerja Karyawan PT PKS Utama Agrindomas Kecamatan Pondidaha Kabuparten Konawe
Authors: Zainuddin Muhammad Zabir , Djauhar Asri , Pratama Jhihad Ajhisya
Published: May 2023

Penelitian ini bertujuan untuk mengetahui pengaruh kompensasi terhadap kinerja karyawan PT.PKS Utama Agrindomas Kecamatan Pondidaha Kabupaten konawe. Penarikan sampel menggunakan rumus slovin sehingga diperoleh sampel terbanyak 54 responden. Metode penelitian ini adalah field research (studi lapangan). Teknik pengumpulan data dilakukan dengan angket, observasi, dan wawancara. Data dianalisis dengan menggunakan analisis regresi linear sederhana. Berdasarkan hasil penelitian dan pembahasan di atas maka diperoleh kesimpulan bahwa, kompensasi berpengaruh positif terhadap kinerja karyawan PT.PKS Utama Agrindomas Kecamatan Pondidaha Kabupaten Konawe, dimana pada hasil uji t diketahui bahwa nilai t-hitung sebesar 2.886 >  t-tabel sebesar 2.006.
Employee Performance in Public Services: Study at the Ranomeeto district office, South Konawe Regency
Authors: Haeruddin  , Jawiah St. , Erfain
Published: May 2023

Pegawai Kantor Camat Ranomeeto Kabupaten Konawe Selatan merupakan salah satu unsur penentu jalan roda penyelenggaran pelayanan publik, dalam  pemerintahan kecamatan. Oleh karena itu, pegawai dalam hal ini sebagai birokrat pemerintah  dituntut  untuk  selalu  menunjukkan  kinerja  baik. Penelitian ini bertujuan  untuk  mengetahui  kinerja  pegawai  dalam  pelayanan  publik. Metode Penelitian dengan menggunakan pendekatan deskriptif kualitatif, teknik analisa data menggunakan model interaktif, teknik pengumpulan data melalui observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa kinerja pegawai pada Kantor Camat Ranomeeto Kabupaten Konawe Selatan dalam penyelenggaraan pelayanan publik telah mencapai kinerja pegawai yang baik.
Prevalence of Hemiplegic Shoulder Pain in Iran: A Systematic Review and Meta-analysis
Authors: Rahmatian Aryoobarzan , Bastani Elham , Shokri Fariba , Karbasfrushan Ali
Published: May 2023

Context: Hemiplegic shoulder pain (HSP) is one of the complications of a stroke. Objectives: This study aimed to determine shoulder pain prevalence in cerebrovascular accident (CVA) patients. Methods: This meta-analysis study searched English and Persian descriptive or descriptive-analytical full-text studies on CVA patients. The search was carried out in all databases by two researchers using keywords such as stroke, pain, CVA, hemiplegic, and shoulder pain. Data analysis was done with the software CMA3. Results: In the initial search, 109 articles were found, and finally, the data from four articles were analyzed. The prevalence of HSP was 23% (confidence interval (CI) = 10.3% - 43.5%). Conclusions: Considering the HSP prevalence (28.1%) among CVA patients, it is necessary to carry out rehabilitation interventions to prevent such pain in these patients. It is also suggested that rehabilitation interventions be included in the patient education of the healthcare system.
Epidemiological, Clinical and Imaging Features of 2019 Novel Coronavirus Diseases (COVID-19) in Southwestern Iran: A Descriptive Study
Authors: Dastoorpoor Maryam , Borsi Seyed Hamid , Khodadadi Narges , Hanafi Mohammad Ghasem , Ahmadzadeh Susan , Zarei Javad
Published: May 2023

Background: Pulmonary Manifestations and damage are one of the most serious problems in COVID-19 patients. Objectives: This study aimed to describe the epidemiological, clinical, and imaging characteristics of patients infected with this virus in the first wave of the COVID-19 epidemic. Methods: By census approach, data were collected from two coronavirus referral hospitals in Ahvaz, the capital of Khuzestan province (southwestern Iran), from June to August 2020. Using a researcher-made checklist, study data were collected: including epidemiological information, signs and symptoms, abnormal chest X-ray and CT-scan findings, underlying conditions and comorbidity, and patient treatment outcome. Results: This study included 375 approved COVID-19 patients with a mean age of 55.5 ± 18.6 years (50.9% male and 49.1% female). The most common underlying diseases included diabetes (23.2%) and cardiovascular diseases (21.9%). Cough (62.4 percent), shortness of breath (57.1 percent), and fever (48.8 percent) were the most frequent symptoms at the start of the disease. In radiographic evaluations, the most prevalent pulmonary involvement manifestations were ground-glass opacity (67.5 percent) and consolidation (81.1 percent) (47.5 percent). The majority of patients (86.9%) had both lungs compromised, with the lower lobes having the highest involvement (61.1 percent). In addition, 45.6 percent of individuals had subpleural involvement. Posterobasal engagement was the most common type of involvement (35.5 percent). Conclusions: In general, the most common clinical and radiological symptoms of this study included cough, shortness of breath, fever, ground-glass opacity, Consolidation and crazy-paving changes, which are consistent with the results of patients with SARS-COV-2 in other parts of the world.
Targeted Solid Lipid Nanoparticles Formulation for Colon Cancer Treatment and Cytotoxicity Assessment Using HT29 Cell Line
Authors: Moghimipour Eskandar , Abedini Maryam , Handali Somayeh
Published: May 2023

Background: Several pharmacological effects have been attributed to thymol. However, limitations such as low solubility in water, low bioavailability, and high volatility have limited its use. Objectives: The present study aimed to prepare and characterize thymol-loaded solid lipid nanoparticles (SLNs) to improve the efficacy of thymol. Methods: Thymol-loaded SLNs were characterized by atomic force microscopy (AFM), differential scanning calorimetry (DSC), and Fourier transformed infrared spectroscopy (FT-IR). Cytotoxicity study and hemolysis assay were also performed. Results: The in vitro drug release showed a sustained manner. Also, SLNs loaded with thymol showed higher cytotoxicity than free thymol, and the hemolysis results indicated the blood biocompatibility of SLNs. Conclusions: As nanocarriers, SLNs can open a new avenue for improving the efficacy of thymol in cancer treatment.
DÜNYADA VE TÜRKİYE’DE KULLANILAN GEÇİCİ AFET KONUTLARININ KARŞILAŞTIRMALI ANALİZİ VE MODEL ÖNERİSİ
Authors: ABANOZ Fatma Berfin , VURAL Nilhan
Published: May 2023

Doğal afetler, uzun yıllardır toplumları pek çok farklı yönde etkilemektedir. Özellikle son yıllarda yaşanan iklim değişiklikleri ve doğal kaynakların tüketiminin bilinçsizce artması, beraberinde doğal afetlerin şiddetlenmesi ve daha sık meydana gelmesine neden olmuştur. İnsanların doğal afetler nedeniyle kendilerini güvende hissettikleri evlerini ve yaşam alanlarını kaybetmesi, hem yaşadıkları olumsuzlukların etkisini artırmakta hem de doğal afet sonrasında normal yaşamlarına dönme süresini uzatmaktadır. Bu kapsamda, doğal afetlerden sonra kullanılan geçici barınma alanları ve bu alanlara konumlandırılan geçici barınma birimlerinin tasarımı ve uygulaması önemli olmaktadır. Geçici barınma birimleri, doğal afetlerden sonra kalıcı konutlar kurulana kadar geçen süre boyunca hizmet veren, afetzedelerin fiziksel ve psikolojik ihtiyaçlarını karşılayabilen temel konut yapılarıdır. Çalışmada, literatüre geçmiş ve doğal afetler meydana geldikten sonraki aşamada ilk olarak kullanılan birimler arasında sayılan standart çadır, konteyner, kâğıt tüp geçici birim, poliüretan iglo ve geçici römork yapıları, strüktür, performans ve kullanım özellikleri başlıklarında analiz edilmiştir. Analizlerin değerlendirilmesi sonucunda, örneklem alanı olarak seçilen Doğu Karadeniz Bölgesi’nde doğal afetlerden sonra kullanılmak üzere yeni bir geçici afet konutu model önerisi getirilmiştir. Yapılan çalışma ile afetlerden sonra kullanılan geçici barınma birimlerinin tasarım ve sürdürülebilirlik potansiyellerinin geliştirilmesi ve geçici barınma yapılarına yönelik yapılacak çalışmalara temel oluşturması hedeflenmektedir.
Dự báo thời hạn bảo quản thuốc phóng pyrocxilin trong điều kiện bao gói kín bằng phương pháp thử nghiệm gia tốc
Authors: Ha Huu Son
Published: May 2023

Standard OCT B 84-2433-90 (Russia) prescribed acceleration method to predict preservation time and using time of pyroxylin propellants. This paper introduces the result of application of the standard to some pyroxylin mark 7/14 in Vietnam conditions based on the decline content of Diphenylamine (DPA). The preservation time was calculated quite reliably.
Sự ức chế ăn mòn thép CT3 trong môi trường axít HCl 2M của 2-[4- hydroxy-3-methoxybenzyliden]-N- phenylhydrazin cacbothioamit
Authors: Nguyen Trong Dan
Published: May 2023

This paper introduces results of synthesis of a new corrosion inhibitor named 2- [4-hydroxy-3-methoxybenzyliden]-n-phenylhydrazincarbothioamide (HMBP). Its corrosion inhibition efficiency for mild steel CT3 in solution HCl 2M were determined by weight loss method, potentiodynamic polarization and electrochemical impedance spectroscopy. All three methods proved that the corrosion inhibitor is high effective to protect mild steel in 2M hydrochloride solution.
Kết quả ứng dụng chế phẩm peptit điều hoà sinh học hỗ trợ điều trị nâng cao sức khoẻ cho nạn nhân chất độc Da cam/Dioxin bị suy giảm miễn dịch
Authors: Hoang Van Huan , Pham Khac Linh , Nguyen Nhu Nghia
Published: May 2023

The article provides some results of researching in supporting the treatment and rehabilitation for verterans who get immune deficiency because of exposing to Agent Orange by the peptides bioregulator produced by Russia Federation. The research shows that the good result of peptides bioregulator application occupies 70%, the goodish one account for 30% and there is complete no negative result. The peptides bioregulator products effect to immune system to increase the immune indexes: IgG, IgM, CD3, CD4 and CD8. The peptides bioregulator products assist veterans treat and improve their health and raise immune ability up without any side effect.
Thành phần khu hệ chó nhà tại tỉnh Hà Giang – Việt Nam
Authors: Bui Xuan Phuong , Trinh Quoc Khanh , Dinh The Dung , Tran Huu Coi , Nguyen Tien Tung
Published: May 2023

The domestic dog fauna in Hagiang province of Vietnam was investigated. It is found that Ha giang domestic dogs are in high proportion and consist of 8 types, among which the H’mong dogs with shortail as a Vietnamese national breed were discovered. The Vietnamese domestic dogs are distributed mainly in high moutains while the group of hybrid and exotic domestic dogs are found mainly in low moutains. The result of the observation shows that the ratio of the male domestic dogs in the young stage is high, but in the adult stage it is low. The breeding method of domestic dogs in Ha giang province is mainly natural, so it is difficult to control the breeding process and veterinary work.
Ảnh hưởng của selen hữu cơ lên sinh trưởng, tỷ lệ sống, thành phần sinh hoá và khả năng miễn dịch của cá Chẽm Lates Calcarifer (Bloch 1790)
Authors: Tran Duc Dien , Tran Minh Sang , Le Minh Hoang
Published: May 2023

To determine the appropriate content of organic selenium in food which can improve biochemical and immune ability of Asian seabass (Lates calcarifer Bloch 1790), a number of fish fry fed in different diets containing Sel-plex supplement concentrations of 0.0 (control), 0.3, 0.5, 0.7 g/kg respectively for 50 days are studied. The research results show that the organic selenium supplementation of 0.5 g Sel-plex/ kg (5.54 mg Se/ kg) proves to be the most appropriate and can improve growth rate, reduce the moisture in the muscles, increase crude protein content, total blood cells THC and resistance to Vibrio parahaemolyticus density of 106 cfu/ml.
Xác định tính ăn mòn khí quyển tại các Trạm Thử nghiệm khí hậu của Trung tâm Nhiệt đới Việt – Nga
Authors: Karpov V.A , Ivonhin V.N. , Chu Minh Tien , Mikhailova O.L. , Covaltruc Iu.L. , Philitrev N.L. , Nguyen Quang Tan
Published: May 2023

This paper presents the the methods to determine the atmospheric corrosiveness by new ISO 9223-2012 standard using the meteorological-environmental parameters or corrosion rate of standard metal samples in 1 year. The meteorological- environmental data of the climatic testing stations of Russian - Vietnamese tropical center and their corrosivenessare are given. In addition the corrosion rate of metal samples in these stations is determined. The meteorological-environmental data and corrosion rate of standard metal samples can predict the lifetime and capacity of metallic details and techniques made of the experimental metalls.
Nghiên cứu quy trình tổng hợp γ-polyoxymetylen
Authors: Bui Thi Hong Phuong , Vuong Van Truong
Published: May 2023

This paper presents the results of preparation of γ-polyoxymethylene (γ-POM) of formaldehyde , which will be used as a components of missile propellants. The average molecular weight of the resulted product γ-POM is 3325 carbon units. The structure of the product is confirmed and its quality complies with the Russian standard TY-84-841-79.
Ảnh hưởng của mật độ ương nuôi đến sự tăng trưởng, tỷ lệ sống của ấu trùng bám bào ngư vành tai (Haliotis asinina Linaeus, 1758)
Authors: Dinh Thi Hai Yen
Published: May 2023

In this study Abalone (Haliotis asinina) spat stage larvae were reared in three different densities: 100, 200 and 300 larvae/stick (equivalent to 1 - 5 units/ml). Food use was Navicula sp. After 30 days of experiment, the results showed that the densities of 100 and 200 spat stage larvae/stick had high growth and survival rate (no statistical difference). The length of the shell size is about 3.27 mm and 3.35 mm having the survival rate is 62.0% and 68.1%, respectively. At that time, with the density of 300 spat stage larvae/stick the length of the shell size is about 2.65 mm and the survival rate is 40.9%.
Thử nghiệm anot magnetite trong hệ thống bảo vệ điện hóa chống ăn mòn vỏ thép tàu biển
Authors: Nguyen Trong Hiep , Nguyen Hong Du , Luu Phuong Minh
Published: May 2023

The paper presents the testing results of magnetite anode used in the impressed current cathodic protection system to prevent corrosion of steel hull in the seawater at Nha Trang bay. Testing results for steel hull with an submerged area of ~ 300 m2 in seawater showed that anodic current reached 0.7 ÷ 1.5 A, the largest anodic current density reached ~ 764 A/m2, the voltage shift of hull is from -156 mV to -259 mV. The voltage of the hull compared to Ag/AgCl reference electrode meets cathodic protection standards in the seawater.
Tạo màng phủ silica lai vô cơ – hữu cơ trên nền hợp kim nhôm
Authors: Ha Huu Son , Nguyen Van Vinh , Nguyen Thi Yen , Nguyen Duc Hung
Published: May 2023

In this work, the hybrid silica coatings on the aluminum alloy have been produced by two methods: dip-coating and electrophoretic deposition. The protective behavior against corrosion of the produced films was studied through polarization curves measurements in aggressive media (3,5% NaCl solution). The corrosion resistance of coatings produced by dipping is much lower than by electrophoretic deposition. The composition and morphology of coatings were also investigated at different heat treating temperatures. The results showed that the heat treatment of the ormosil coatings after electrophoretic deposition is necessary at the temperature not higher than 400oC.
Quan trắc dl-PCB theo mùa bằng thiết bị lấy mẫu không khí thụ động với phin lọc PUF
Authors: Trinh Khac Sau , Nguyen Thi Thu , Nguyen Thi Dung
Published: May 2023

We have carried out seasonal monitoring of twelve congeners of dioxin like-PCB (dl-PCB) in urban ambient air in Hanoi using passive air sampler with polyurethane foam (PUF) filter. 13C-labeled dl-PCB surrogate standards have been added on the PUF filters at the beginning of sampling to evaluate the efficiency of dl-PCB retention during the monitoring period. Most of 13C-labeled dl-PCBs are stable and well maintained on the PUF filters in all seasons. In general, the efficiency of their retention ranged from 27.2% to 190%. The concentration of native dl-PCB congeners, which found on PUF filters with or without 13C-labeled dl-PCBs in different seasons have a coefficient of variance ≤ 35%. It means that this sampling method has good replication. Profile of dl-PCBs in ambient air in the study area has been determinated. PCB#118 always has the highest concentration from 15.3 to 62.4 pg/filter/day. Total TEQdl-PCBs highest is 0.063 pg/filter/day in winter of 2013. The results indicated that seasonal monitoring of dl-PCBs may be carried out by using passive air sampler with PUF filter in the tropical climate in Northern Vietnam.
Hiệu quả điều trị trẻ tự kỷ bằng phương pháp oxy cao áp
Authors: Nguyen Phuong Nam , Do Thi Bich Ha , Cao Trung Thanh , Tran Duc Huynh
Published: May 2023

Fifty children with autism, 43 boys and 7 girls, aged from 2 to 10 (mean 4.9 ± 2), underwent 40 hyperbaric sessions of 60 minutes duration for each at 1.5 atmospheres and 100% oxygen. Outcome measures after 40 sessions were changed compared to pre-treatment scores and post-treatment scores for each child using the Autism Treatment Evaluation Checklist (ATEC). After 40 hyperbaric sessions, statistically significant improvements were observed on the ATEC scores (p < 0.001). The average improvement in all children were on the ATEC total score 21.8% (p < 0.001), speech/language/communication 15.8% (p < 0.001), sociability 21.9% (p < 0.001), sense/cognitive awareness 15.9% (p < 0.001), and health/physical fitness/behavior 31.6% (p < 0.001).
Đặc điểm phân bố và môi trường sống của loài Sâm đất (Phascolosoma arcuatum, Gray 1828) tại rừng ngập mặn Cần Giờ
Authors: Le Thi Hong Tham , Phan Xuan Thinh , Nguyen Tuan Anh , Truong Ba Hai , Truong Trong Hung
Published: May 2023

The results of the study on the distribution and environmental characteristics of Peanut Worms (Phascolosoma arcuatum, Gray 1828) in Can Gio mangrove forest show that: Peanut Worms live in the areas which have flood level < 1m, flood time < 30%, the topography from 0.8m to 1.7m and in the depth from 10 cm to 30 cm. They live in the soil from silty clay loam to clay which is quite porous, high humid, from acidic to neutral, organic-rich, heavy salty and less aluminous. The average density of the Peanut Worms is 7.44 individual/m2. Peanut Worms density in mixed mangrove forest is higher than that in planting Rhizophora apiculata forest and depends on the compartments. It is forecasted that the distribution area of Peanut Worms in Can Gio mangrove forest is about 24,323 ha and the caches of Peanut Worms are about from 285,600 kg to 535,500 kg/year.
Ảnh hưởng của thức ăn, chế độ cho ăn lên sinh trưởng và tỷ lệ sống của tu hài (lutraria rhynchaena jonas, 1844) giai đoạn xuống đáy đến kích cỡ 5mm
Authors: Phan Thi Thuong Huyen , Ngo Anh Tuan , Phung Bay , Nevejan Nancy , Huynh Duc Tam
Published: May 2023

This report presents the results of two studies on the effects of different algae species foods and food diets on the growth and survival rate of otter clam from the spat stage to 5mm- seed stage. The 5 algae species used to feed otter clam were Isochrysis galbana, Dicrateria sp, Chaetoceros calcitrans, Skeletonema costatum, Tetraselmis chuii. They were combined into four different trials, among them Tetraselmis chuii is used in all trials. The 36 day-trial result shows that the size and survival rate of otter clam in the trial done with Isochrysis galbana + Chaetoceros calcitrans + Tetraselmis chuii are the best (5.238 ± 2,22μm, 50,1 ± 1,46%). The otter clam spat was fed with four different food diets including (35.000; 40.000; 45.000; 50.000 cells/mL/day); (70.000; 80.000; 90.000; 100.000 cells/mL/day); (105.000; 120.000; 135.000; 150.000 cells/mL/day); (140.000; 160.000; 180.000; 200.000 cells/mL/day) at day periods respectively 1-7; 8-14; 15- 21; 22-5mm-seed. As a result, in the diet of 105.000; 120.000; 135.000; 150.000 cells/mL/da at 1-7; 8-14; 15-21; 22-36 days respectively, the size and survival rate of otter clam spat are the best (5.757± 5,7 μm, 51,1± 0,43%).
Nghiên cứu chuyển hóa zerumbone oxit với một số axit hydrazid thơm
Authors: Vuong Van Truong , Pham Duy Nam , Trinh Thi Thuy Lien , Pham Thi Duyen , Nguyen Dang Dat
Published: May 2023

Zerumbone was isolated from several plant species of the Zingiberaceae family which have many potential biological activities, such as antiproliferative, antioxidant, anti-inflammatory, and anticancer activities. Due to these biological effects, many scientists have managed to synthesize zerumbone derivatives and evalute their bioactivities. In this paper, we report some results in the synthesis of six new zerumbone derivatives by the condensation of zerumbone oxide with aromatic hydrazides. The structures of these compounds have been confirmed by 1H NMR, 13C NMR and ESI-MS spectroscopic data.
Nghiên cứu ảnh hưởng của một số phụ gia bê tông đến ăn mòn cốt thép trong môi trường nước biển Tiếp theo Nghiên cứu chuyển hóa zerumbone oxit với một số axit hydrazid thơm Trả lời
Authors: Vu Dinh Huy , Bui Ba Xuan , Luu Hoang Tam , Nguyen Ba Tai , Phan Ba Tu
Published: May 2023

In the study natural tests of reinforced concrete samples contained corrosion inhibitors including sodium silicate, urea, thiourea (in the concentrations: 0, 0.05, 0.10, 0.15 and 0.20%) and silica fume (in the volume of 0; 2.5, 5.0, 7.5 and 10%) in the Vietnam tropical sea have been carried out and the effects of depth and their nature and concentration on the corrosion behavior of Pomina and Vina carbon steels embedded in concrete after 01 month of testing were investigated. It is found that the corrosion protection effectiveness (η) of the four inhibitors are η (Thiourea) > η (Urea) > η (Sodium silicate) > η (Silica fume). The steel-reinforced corrosion activity of the sea at the depth of 0.5 m was higher than that at the depth of 1m.
Nghiên cứu điều kiện lao động và một số chỉ số sinh lý của phi công quân sự Việt Nam lái các loại máy bay hiện đại do Liên bang Nga sản xuất
Authors: Pham Xuan Ninh , Tran Thanh Tuan , Le Tien Hai , Nguyen Minh Hai
Published: May 2023

This paper studies the working conditions, physiological parameters of 53 Vietnam military pilots, who flies Russian modern jet aircraft such as MIG-21, SU- 27, SU-30. The results showed that many adverse factors of the labour environment (overload, acceleration, radiation, heat, humidity, noise), the complicated flight tasks and nerve-psychological stress can affect their health during flying period. The microclimatic indexes are higher than the norms and impact directly on the cardiovascular and central nervous system of pilots affecting the functions of organism work capacity and professional health of the pilots.
Nghiên cứu ảnh hưởng của bột nhôm đến một số tính chất của thuốc nổ nhũ tương
Authors: Nguyen Van Tinh , Dam Quang Sang
Published: May 2023

The article studies the effect of aluminum powder (with different content and particle size) on some significant properties of emulsion explosive such as density, water resistance, detonation velocity and heat of explosion. The calculated data and experimental results show that the density, heat of explosion and detonation velocity of the emulsion explosive with aluminum powder as an energy additive which is less than 10% of the content are higher than those without aluminum powder, while its water resistance decreases. It is proved that aluminum powder can be completely used to impove the detonation energy of emulsion explosive with paying attention to its low water resistance when conduct underwater blasting.
Giá trị đóng góp của hệ sinh thái rừng nhiệt đới Nam Cát Tiên đối với khí hậu thông qua giám sát sự trao đổi của các dòng nhiệt lượng và CO2
Authors: Dinh Ba Duy , Avilov V.C , Kuricheva O.A. , Kurbatova J.A. , Le Xuan Son , Dao Thi Thu Huong , Nguyen Thi Chinh , Tran Thi Nhan
Published: May 2023

Monitoring the exchanges of CO2 and energy between terrestrial ecosystems and the atmosphere is one of the approaches with high accuracy to quantify the contribution of tropical rainforest to climate. The results of the study in Nam Cat Tien forest ecosystem from 2012 to 2014 illustrate that this ecosystem plays the role of carbon sinks during 11 months in a years (over 90%) and the average uptake reaches 455,8 gC/m2. In addition, about 74% of the net radiation (155,8 W/m2) that the ecosystem obtainsis transformed into latent heat and about 23% into sensible heat thanks to the ability to restrict surface flow, fix groundwater and remain moisture at the high level.
Nghiên cứu đa dạng sinh học nấm mem nội sinh phân lập trên chuối Tiêu hồng Musa sapientum L. tại khu vực Gia Lâm, Hà Nội
Authors: Chu Thanh Binh , Do Thi Thu Hong , Ngo Cao Cuong
Published: May 2023

20 endophytic yeast strains are isolated from 41 samples of flower, young fruit, old fruit of bananas Musa sapientum L.. The strains are divided into 16 groups based on morphological characteristics. The number of the endophytic yeast having cellulase, protease and amylase activity is 16, 15 and 6 respectively. When the endophytic yeast strains are studied by fingerprinting, they belong to 15 groups with high reliability.
Tuyển chọn các chủng vi khuẩn tiềm năng cho lên men sinh axít lactic
Authors: Vu Xuan Nam , Do Tat Thinh
Published: May 2023

Lactic acid bacteria is used in many areas. In this study, 49 strains of lactic acid bacteria were isolated from the vegestable, fruit, and fermented food. Among them 3 potential homo-fermentative strains were selected and one strains can produce lactic acid with the concentration of 33.9 g/l in the MRS medium containing 40 g/l glucose with the yield of 87% at 37oC.
Nghiên cứu một số yếu tố môi trường trong hầm phẫu tại quần đảo A và ảnh hưởng tới sức khoẻ bộ đội
Authors: Hoang Van Huan , Duong Van Thien , Nguyen Van Chuyen , Tong Duc Minh , Pham Ngoc An
Published: May 2023

The values and average changes of some microclimate factors inside surgery tunnels in the A Islands have been determined: WBGT ranges from 29.5 to 31.7°C, light intensity is below hygiene standards (50.8 to 437.2 lux); O2 and CO2 concentrations change rapidly according to the number of working soldiers and time trial. After 120-minute-test, there appear the signs of thermal and emotional stress affecting the cognitive ability, information-processing ability and short term memory of the soldiers.
Изучение защитных свойств ингибированной пленки на основе ингибитора ифхан-112 в условиях влажного тропического климата
Authors: Ануфриев Н.Г. , Карпов В.А. , Филичев Н.Л. , Фан Ба Ты
Published: May 2023

Polyethylene film made from the basis of a volatile corrosion inhibitor IFKHAN-112 (3.0% and 4.5% by weight) was exposure to a preliminary assessment of its effectiveness of protection against atmospheric corrosion of St3 steel, M1 copper, Ts0 zinc and D16 aluminum alloy. Natural weathering test was conducted on Natural Weather Testing Station Dam Bay over the period of 12 months. The station is located in humid tropical climatic conditions. It was shown that the contact method provided almost complete protection for St3 steel in the period of 6÷12 months, whereas the vapor-phase method - only 6 months. Both methods provided a high protective level for copper and zinc (M1, Ts0) in the period of 6÷12 months. Inhibiting film IFKHAN-112 did not provide full protection for D16 aluminum alloy against the atmospheric corrosion.
Nghiên cứu chế tạo sáp phức hợp dùng trong sản xuất thuốc nổ nhũ tương
Authors: Ha Ngoc Thien , Vuong Van Truong , Nguyen Duc Nghia , Nguyen Tho Truong , Le Khac Dao
Published: May 2023

Compound wax is an important component which plays role as fuel phase, emulsifier in the manufacture of emulsion explosives. In this article, we reported the results of studying on the effects of the content of span-80, paraffin, mineral oil in the compound wax to its emulsifying ability, density and porosity of emulsion explosives. Emulsify explosive produced on the compound wax SVN-01 (20% span-80, 40% paraffin, 25% vaselin and 15% mineral oil) was characterized as high explosive velocity, compressible degree of the lead cylinder. The stability of the explosive in 6 thermal cycles (24 hours at -18oC and 24 hours at +60oC) compared to the control sample of 3 thermal cycles.
Chế tạo và thử nghiệm thỏi nhiên liệu tên lửa rắn sử dụng phụ gia cháy Diethyl Ferrocen do Việt Nam sản xuất
Authors: Nguyen Duc Long , Pham Duy Nam , Vuong Van Truong
Published: May 2023

Diethyl ferrocene is an important additive used in solid missile fuel. It plays role as a burn rate modifier in fuel component. It is not only an excellent catalyst, but also a good plasticizer in producing solid missile fuel. This article showed some results from using diethyl ferrocene Viet Nam in manufacture of solid missile fuel.