bluuebunny/crossref_metadata_2025 huggingface dataset:
THAILAND’S HEDGING STRATEGY UNDER THE STRATEGIC COMPETITION BETWEEN CHINA AND THE UNITED STATES
Authors: Feng Yongping , Netkhunakorn Chanattaporn
Published: May 2024

Thailand's foreign policy stance has shifted dramatically since the Prayuth regime staged a coup in 2014. The purpose of this study: 1) Complement and expand on the theoretical meaning of hedging strategy. 2) It can theoretically support Thailand in the face of strategic conflict between China and the United States. 3) Be aware of why Thailand implements a hedging strategy and know the specific performance of Thailand’s hedging strategy. 4) It will aid in the growth of Thailand's connections with the two big countries. 5) This article can provide certain reference for research related to Thailand’s diplomatic strategy. The method of this study adopts content documentary analysis, case analysis method, literature research and historical method.
According to the findings of this study, Thailand has begun to tilt more toward requesting assistance from China in Prayuth goverment. Many researchers are concerned about Thailand's neutrality. However, Thailand has not yet vanished from the United States. Just a few steps removed from the Obama and Trump administrations. Thailand has begun to rebuild its old friendship with America as the Joe Biden era looms. But anyway Thailand cannot choose a side. Because Thailand is a reliable ally on both sides. This has caused the Prayut government to seek cooperation from other organizations and countries, including Japan, India, and ASEAN. Thailand has accelerated the development of economic links with Japan. Accelerate the political development of relations with India. and establishing ties with ASEAN and Southeastern countries in order to find a way for small countries to maintain their own interests as much as possible in the fight between the two superpowers. Although hedging techniques are currently the preferred option for smaller countries, the variables driving this strategy differ. In Thailand, the majority of the factors that influence hedging tactics originate within the country. But all bordering countries are influenced by foreign causes. As a result, Thailand has become another special case of hedging among ASEAN countries.
Civilian Coping Strategies in War
Authors: Middendorf Greta
Published: May 2024

This paper aims to gain further understanding of civilian experiences of war by analyzing a diary written during the siege of Breslau in 1945. This study seeks to address two key issues. Firstly, the current Peace and Conflict Studies literature lacks integration of theories from psychology, which could help gain insights into civilian coping strategies in war. Furthermore, civilian war experiences should be addressed in their historical context. Drawing from Suedfeld et al.’s (1997) adapted Ways of Coping Scale, which derives from Lazarus’ and Folkman’s (1984) theory on psychological stress and coping, a directed, qualitative content analysis explores the coping strategies used by the diarist. The study finds that the diarist mostly employs problem-oriented coping strategies, focusing on altering the threat, consisting of escaping from bombs, analyzing, preparing for, and altering the damage caused by artillery and seeking social support. Emotion-oriented coping, aimed at regulating the emotional response to a threat, mostly shows through denying the threat to maintain sleep and normality, and through distancing oneself from the threat through humor, hope, and a positive attitude. My findings form a base to adapt Suedfeld et al.’s Ways of Coping Scale to better assess civilian coping strategies in war.
Gambaran CT Scan Kepala Sentrasi Orbita pada Pasien Proptosis
Authors: Muse Musdalifah , Marlyanti Nur Rahma  , Raden Selma  , Suliati P. Amir  , Lidya Paulina Christina
Published: May 2024

Proptosis adalah suatu keadaan dimana bola mata menonjol ke depan dan merupakan gejala klinis dari berbagai patologi di dalam maupun diluar ruang orbita. Proptosis dapat dinilai menggunakan pemeriksaan CT Scan kepala sentrasi orbita sekaligus dapat mengetahui etiologi dari proptosis. Tujuan penelitian ini untuk mengetahui gambaran CT Scan kepala sentrasi orbita pada pasien proptosis di RSUP Dr. Wahidin Sudirohusodo periode tahun 2020 - 2022. Desain penelitian ini adalah deskriptif observasional yang menggunakan rekam medik sebagai data sekunder. Teknik pengambilan sampel yaitu menggunakan rumus slovin sehingga diperoleh jumlah sampel sebanyak 36 pasien proptosis pada bulan Agustus – September 2023 bertempat di RSUP Dr. Wahidin Sudirohusodo. Dari 36 penderita proptosis menunjukkan distribusi usia paling tinggi didapatkan pada  ussia  >40 tahun (47,2%) lalu diikuti dengan usia 20-40 tahun  (38,9%) dan yang terendah pada usia <20 tahun (13,9%), berdasakan jenis kelamin proptosis banyak didapatkan pada laki-laki 19 orang (52,8%) dibandingkan perempuan 17 orang (47,2%). berdasarkan etiologi, tumor adalah penyebab terbanyak 26 orang (72,2%) lalu diikuti etiologi vaskular 9 orang (25,0%), dan etiologi other 1 orang (2,78%), dan berdasarkan lateralisasinya proptosis banyak didapatkan pada lateralisasi unilateral 34 orang (94,4%) dibandingkan lateralisasi bilateral 2 orang (5,6%). Pada penelitian ini distribusi proptosis terbanyak yaitu usia >40 tahun, etiologi tumor, jenis kelamin laki-laki dan lateralisasi unilateral.
Prevalensi dan Gambaran Pasien Low Back Pain pada Lansia
Authors: Muzammilia Nadraini  , Imran Safei  , Prema Hapsari Hidayati  , Achmad Haruns Muchsin  , Zulfiyah Surdam
Published: May 2024

Low back pain (LBP) merupakan penyakit muskuloskeletal yang disebabkan oleh ergonomi yang buruk dan sering ditemukan pada seseorang dengan lanjut usia (lansia). Seiring bertambahnya usia, kekuatan otot akan semakin berkurang akibat kerusakan jaringan tubuh, terlebih akibat beberapa faktor risiko, seperti faktor usia, jenis kelamin, Indeks Massa Tubuh (IMT), gangguan psikologi, adanya penyakit komorbid, dan aktivitas sehari-hari seperti posisi serta masa kerja. Tujuan penelitian ini adalah untuk mengetahui prevalensi dan gambaran pasien LBP pada lansia di RSUD Sinjai Tahun 2022. Penelitian ini merupakan penelitian deskriptif dengan pendekatan retrospektif berdasarkan data sekunder rekam medis di RSUD Sinjai Tahun 2022. Hasil dari penelitian ini didapatkan pasien LBP pada lansia di RSUD Sinjai berdasarkan usia paling banyak adalah kelompok usia 60-75 tahun (elderly/lanjut usia) sebanyak 44 pasien, jenis kelamin perempuan sebanyak 32 pasien, pekerjaan ibu rumah tangga (IRT) sebanyak 13 pasien, nyeri akut sebanyak 37 pasien, nyeri menjalar sebanyak 28 pasien, nyeri mengganggu sebanyak 36 pasien, tidak memiliki komorbid sebanyak 34 pasien, disebabkan oleh Hernia Nukleus Pulposus (HNP) sebanyak 14 pasien, tidak merokok sebanyak 41 pasien, tidak menggunakan alat bantu sebanyak 49 pasien, dan mengalami gangguan fungsi tubuh sebanyak 20 pasien. Sehingga dapat disimpulkan bahwa prevalensi pasien LBP pada lansia di RSUD Sinjai yaitu sebanyak 52 pasien, dengan distribusi terbanyak didapatkan pada kelompok usia 60-75 tahun (elderly/lanjut usia), jenis kelamin perempuan, pekerjaan IRT, mengalami nyeri akut, nyeri menjalar, nyeri mengganggu, tidak memiliki komorbid, disebabkan oleh HNP, tidak merokok, tidak menggunakan alat bantu, dan mengalami gangguan fungsi tubuh.
Karakteristik Penderita Ulkus Kaki Diabetik
Authors: Nurlana Zamaun  , Indah Lestari Daeng Kanang  , Muhammad Imran  , Darariani Iskandar  , Erick Gamaliel Amba
Published: May 2024

Diabetes Melitus (DM) adalah suatu kelompok metabolik yang ditandai dengan peningkatan kadar glukosa darah yang melebihi normal. Komplikasi DM yang paling umum terjadi adalah Ulkus Kaki Diabetik (UKD). Prediksi International Diabetis Federation (IDF) jumlah penderita DM tipe 2 di Indonesia terus meningkat. Penelitian ini bertujuan untuk mengetahui karakteristik penderita UKD di Rumah Sakit Ibnu Sina Makassar Tahun 2018 - 2022. Jenis penelitian yang dilakukan adalah penelitian observasional dengan data sekunder yang bersumber dari data rekam medis. Populasinya adalah semua pasien UKD yang terdata di Rumah Sakit Ibnu Sina Makassar sehingga sampel penelitian ini diperoleh dengan metode total sampling, yaitu seluruh populasi penelitian ini berjumlah 34 pasien. Sampel disesuaikan dengan kriteria inklusi dan ekslusi. Hasil pada penelitian ini didapatkan prevalensi UKD bedasarkan klasifikasi Meggit – Wagner paling banyak pada derajat 3 dengan jumlah 18 kasus (52,9%), usia penderita UKD paling banyak pada usia 45 – 59 tahun 20 kasus (58,8%), jenis kelamin terbanyak adalah perempuan 19 orang (55,9%), Indeks Massa Tubuh (IMT) tersering dengan IMT normal sebanyak 24 orang (70,1%), jenis pengobatan yang paling banyak digunakan adalah insulin dengan jumlah 33 orang (97,1%), lama menderita DM yaitu >5 tahun sebanyak 18 orang (54,5%), Gula Darah Sewaktu (GDS) 300 - ≤400 sebanyak 11 kaus (32,3%), dan kadar HbA1c yang tidak terkontrol >7% sebanyak 34 kasus (100%). Ulkus kaki diabetik paling banyak didapatkan dengan derajat 3, usia 45 – 59, jenis kelamin perempuan, IMT normal, jenis pengobatan insulin, lama DM lebih dari 5 tahun, GDS 300 - ≤400 dan HbA1c >7% tidak terkontrol.
Gambaran Tingkat Pengetahuan Tentang Resusitasi Jantung Paru Mahasiswa Teknik Pencinta Alam
Authors: Latif Elfatri , Fendy Dwimartyono  , Alamsyah Ambo A.H  , Wirawan Harahap  , Kartika Handayani
Published: May 2024

Kejadian Henti napas dan henti jantung merupakan bentuk kegawatdaruratan yang harus mendapatkan penanganan yang tepat dan segera dari medis atau masyarakat umum yang terlatih. Henti Jantung dapat dipulihkan jika tertangani segera dengan Resusitasi Jantung Paru (RJP) dan defibrilasi untuk mengembalikan denyut jantung normal dimana RJP dapat dilakukan oleh siapa saja mulai dari orang awam sampai dokter, dimana saja, kapan saja dan tanpa mempergunakan alat dapat diterapkan pada keadaan darurat. Penelitian ini bertujuan untuk mengetahui gambaran tingkat pengetahuan tentang RJP pada mahasiswa Teknik Pencinta Alam Universitas Muslim Indonesia (UMI). Jenis penelitian ini adalah dekspriptif dengan desain cross sectional. Jumlah sampel yang digunakan pada penelitian ini berjumlah 109 orang mahasiswa. Pada penelitian ini didapatkan tingkat pengetahuan dari 109 sampel tertinggi didapatkan 81 (74,3%) berpengetahuan baik, terendah 3 (2,75% dengan pengetahuan kurang. Berdasarkan jenis kelamin pengetahuan laki-laki dari jumlah 72 orang sebanyak 54 (75%) dengan pengetahuan baik dan perempuan dengan jumlah 37 orang sebanyak 27(73%) berpengetahuan baik. Berdasarkan sumber informasi tertinggi didapatkan melalui saudara/keluarga/teman sebanyak 43 (39,45%) dan terendah melalui media elektornik yaitu 7 (6,42%). Berdasarkan riwayat pengalaman tertinggi ditemukan sebanyak 70 (64,22%) tidak ada pengalaman, 29 (26,61%) dengan riwayat pengalaman henti napas dan henti jantung dan terendah sebanyak 20 (9,17%) dengan riwayat pengalaman henti napas. Mahasiswa Teknik Pencinta Alam UMI memiliki tingkat pengetahuan yang baik mengenai RJP baik yang memiliki pengalaman maupun tidak.
Pengaruh Dangke pada Perubahan Neutrofil to Lymphocyte Ratio Tikus Putih Obesitas
Authors: Alya Muthia Nur Amari Natsar  , Asrini Safitri  , Rezky Pratiwi L Basri  , Sri Julyani  , Irna Diyana Kartika Kamaluddin
Published: May 2024

Obesitas dikaitkan dengan peradangan.  Penelitian sebelumnya telah menemukan bahwa obesitas ditentukan oleh Indeks Massa Tubuh (IMT) dan Lingkar Pinggang (LP) dikaitkan dengan peradangan. Dangke mengandung Bakteri Asam Laktat Indigenos. Keberadaan bakteri asam laktat dalam produk fermentasi memiliki manfaat yang sangat positif bagi kesehatan. Fungsi getah papaya yang digunakan pada pembuatan dangke, memiliki kemampuan sebagai bahan antibakteri dan anti-inflamasi. Untuk Menganalisis pengaruh dangke pada perubahan kadar NLR pada tikus putih obesitas. Penelitian experimental murni dengan desain yaitu Pre-Post Randomized Clinical Trial Desain. Experimen ini dilakukan dengan tujuan untuk melihat perlakuan sebelum dan sesudah diberikan dangke pada kadar NLR tikus Obesitas. Analisis data dengan menggunakan uji independent T-test/Mann-whitney test dengan nilai <0,05. Perbedaan rata-rata kadar NLR kelompok Intervensi dan kontrol didapatkan nilai-p sebesar 0,94 yang artinya tidak ada hubungan kontrol dan intervensi terhadap kadar NLR. Perubahan rata-rata kadar NLR pada kelompok kontrol nilai-p sebesar 0,61 yang artinya tidak ada perubahan kadar NLR yang signifikan pada test 1 dan test 2. Perubahan rata-rata kadar NLR pada kelompok intervensi sebelum dan sesudah diberikan intervensi nilai-p sebesar 0,07 yang artinya tidak ada perubahan kadar NLR yang signifikan pada kelompok intervensi. Tidak ada pengaruh yang signifikan, kadar NLR pada kelompok kontrol dan kelompok intervensi, terhadap pemberian dangke.
FEA of stress-strain state and vibrations of a three-layer plate
Authors: Lavrenko Iaroslav , Sushchenko Maksym
Published: May 2024

Solar panels are considered as three-layer plates with a thick, rigid outer layer and a thin, soft inner layer. The model for anti-sandwich plates was used to describe the mechanical behavior of the plates in the example of a solar panel. The literature review includes scientific articles describing models for analytical and numerical calculations of three-layer plates. During the scientific study of the mechanical behavior of the solar plate under the influence of external factors, the finite element analysis method for multilayer plates was used. The shell elements were used to calculate and model the natural waveforms of three-layer plates. The paper presents scientific research under static loading under various conditions of influence, analyzes the natural frequencies, and vibration forms, and investigates the stress-strain state depending on the vibration frequencies of the three-layer plate. As part of the scientific work, a mechanical model of a thin solar panel was studied using finite element analysis in the ANSYS program, taking into account various temperature conditions and comparing the results with existing studies.
Starfsumhverfi og helstu aðferðir íslenskra verkefnastjóra
Authors: Ingason Helgi , Grétarsson Jón
Published: May 2024

Í rannsókn þessari er leitast við að bregða ljósi á starfsumhverfi verkefnastjóra á Íslandi auk þess að skapa yfirlit yfir helstu aðferðir sem verkefnastjórar á Íslandi nota. Gagna var aflað með því að senda út könnun á stóran hóp fólks sem hlotið hefur alþjóðlega vottun í verkefnastjórnun á vegum Verkefnastjórnunarfélags Íslands. Í ljós kom að flestir þeirra starfa hjá fyrirtækjum sem teljast stór á íslenskan mælikvarða og þeir stýra verkefnum sem eru á annað hundrað milljónir að fjárhagslegu umfangi og taka að jafnaði ár eða styttri tíma. Ennfremur kemur í ljós að umboð þessara verkefnastjóra til ákvarðana í þeim verkefnum sem þeir stjórna er takmarkað. Umboð karlkyns verkefnastjóra er þó sterkara en umboð kvenkyns verkefnastjóra, starfsreynsla þeirra er lengri og fjárhagslegt umfang verkefna sem þeir stýra er meira. Algengustu aðferðir verkefnastjórans samkvæmt þessari könnun eru verk- og tímaáætlun, kostnaðaráætlun, ræsfundur, áhættugreining, verklýsing, formleg lúkning verkefnis og þarfagreining. Dæmi um aðferðir sem þátttakendur telja að myndu hafa jákvæð áhrif á niðurstöðu verkefnis ef notkun á þeim væri aukin eru skýr afmörkun og umfang verkefnis, samskiptaáætlun og skipurit, kostnaðaráætlanir, mannleg samskipta- og leiðtogahæfni, hluttekning og virk hlustun, þarfagreining, hagsmunaaðilagreining, verk- og tímaáætlunarhugbúnaður og ýmis verkefnastjórnunarkerfi. Litlar breytingar hafa orðið á þessari upptalningu frá sambærilegri könnun árið 2012.
تأثير تمرينات المرونة لتأهيل المصابين بالتحدب الظهري للبنين
Authors: Prof. Dr. Basil Abdel Sattar Ahmed  , Kadhem Yasser Kadhem
Published: May 2024

تهتم الدول المتقدمة في العالم اهتماما واسعا بجميع أفراد شعبها بمختلف اعمارهم وتعمل على توفير الرعاية الصحية لهم حيث تقدم جميع الخدمات لمواطنيها وهي مدركة تماما أن كل ذلك سوف يرتد إليها أضعافا مضاعفة. ويعد المستوى الصحي والبدني للشعب أحد اهمم قايس التقدم والرقي لكل شعب، فالشعب الذي تعلو وجوه أفراده البسمات وتمتاز أجسامهم بالقوة والصحة هو الشعب الذي ينتظره المستقبل المشرق المزدهر، تهدف تمارين الإطالة أو تمارين المرونة والمطاطية إلى زيادة مطاطية العضلة ومرونة المفاصل، وخاصةً في حالات قصر العضلات أو الالتصاق الذي يعيق حركة الجزء المصاب، كذلك حالات تيبس المفاصل عند الالتئامان غير الصحيحة بعد الإصابات المفصلية، اذ يعد التحدب الظهري المصاحب من التشوهات الشائعة التي تصيب العمود الفقري بمرحلة مبكرة من مراحل العمر. لذا يمكن تعريف التحدب الظهري على انه "الوصف المبالغ للانحناء السهمي الموجود في المنطقة الصدرية من العمود الفقري، وهذه مشكلة تصيب الاشخاص في وقت مبكر من العمر ما بين (16-18)سنة، لذلك ارتائ الباحثان الخوض في هذه المشكلة وتصميم تمرينات تؤهل هذه الاصابة قدر المستطاع،  لذلك اعتمد الباحثان المنهج التجريبي للعينة ضمن تصميم  المجموعة الواحدة، وقد تم إجراء التجربة الاستطلاعية في مستشفى الخالص العام/ قسم العلاج الطبيعي على (1) من المصابين خارج عينة البحث للتأكد من قدرة على اداء التمارين في الرياضة العلاجية والتعرف على قدرة فريق العمل المساعد، وبعد الحصول على النتائج قام الباحثان بمعالجتها عن طريق استخدام الحقيبة الاحصائية spss وبعد تحليل النتائج توصل الباحثان إلى استنتاجات أهمها ، فاعلية تمرينات المرونة في تأهيل اصابة التحدب الظهري.
Diversifierade dåtider
Authors: Ramadani Åslund Albin , Fredriksson Daniel
Published: May 2024

Utifrån begreppet kronotop så analyseras Garmarnas och Hedningarnas strategiska bruk av semiotiska resurser. Banden brukar dessa resurser för att knyta an till en dåtid samtidigt som de distansierar sig från den: på så sätt skapar de unika världar utifrån bruket av den folkmusikaliska traditionen.
Kombinasi Metode Entropy dan Simple Additive Weighting (SAW) dalam Pemilihan Dosen Pembimbing Skripsi
Authors: Nisa Halimatun , Aulia Fitrahuda , Rayhan Annisa
Published: May 2024

In the preparation of the thesis, students need a supervisor as a place of consultation in completing the thesis. The supervisor should be a person who mastered the field in accordance with the topic of student thesis, so that the guidance process can run optimally. Thesis is one of the graduation requirements to obtain a bachelor's degree. Generally, the selection of thesis supervisors is decided by the study program through a meeting of lecturers to determine which lecturers are in accordance with the title and description of the students who took the thesis course. To solve this problem, a solution is needed that can take into account the specifications of lecturer expertise that suits the needs of students. The Entropy method is an alternative to solve this problem. This method was chosen because it is able to select the best alternatives from a number of alternatives, in this case the intended alternative is to be a supervisor and examiner based on the specified criteria. Research is carried out by looking for the weight value for each attribute, then a casting process is carried out that will determine the optimal alternative, namely the four lecturers whose specification values are highest.Keyword: Decision Support System, Entropy, Thesis
Perancangan Pembangkit Listrik Tenaga Surya Dengan Sudut Panel Optimal Sebagai Sumber Energi Listrik Pada Area Keramba Jaring Apung Padang Cermin
Authors: Nugroho Bagus Agung , Setyawan F.X Arinto , Yudamson Afri
Published: May 2024

Indonesia's seas hold abundant natural resources and are a highly desirable location for marine fish farming, especially among fishermen. One of the most common methods used in this activity is the use of floating net cages. However, an obstacle faced by fishermen is limited access to electrical energy at the cage sites which are generally far from settlements. This research aims to design a Solar Power Plant (PLTS) in order to meet the electrical energy needs of fishermen in the floating net cage area. The focus of the research is on the design and assembly of the PLTS system with an emphasis on setting the optimal panel angle. The panel angle is calculated based on the amount of radiation received by the inclined plane surface, utilizing geographic location data obtained from NASA SSE. The results show that the proposed solar power plant design can meet the electrical energy demand in the floating net cage area. In practical implementation, the daily energy requirement of 481 Wh for lighting and automatic feeding devices can be met by using a 100 Wp solar PV system, with a battery storage capacity of 46 Ah. Furthermore, the determination of the optimal tilt angle, based on radiation and geographical factors at the location of floating net cages, is about 6 degrees, with a radiation value of 57.38848 kWh per year at the location of Padang Cermin, Durian District.
Analisis Perbaikan Peralatan Pada Sistem Server Atis Pylot Berupa Broadcast Data Cuaca Yang Tidak Diterima Oleh Pesawat
Authors: Rahmadani Eldo Tri Rahmadani , Wildan Muh , Azka Muizuddin
Published: May 2024

Berdasarkan Undang-Undang Nomor 1 Tahun 2009 Tentang Penerbangan dan Peraturan Menteri Perhubungan Republik Indonesia Nomor 57 Tahun 2011 Tentang Peraturan Keselamatan Penerbangan Sipil Part 171 (Civil Aviation Safety Regulation Part 171) tentang Penyelenggara Jasa Telekomunikasi Penerbangan (Aeronautical Telecommunication Service Provider) ) sebagaimana telah diubah terakhir dengan Peraturan Menteri Perhubungan Nomor PM 38 Tahun 2014 yang menyatakan bahwa jasa komunikasi penerbangan terdiri atas jasa siaran penerbangan, jasa penerbangan tetap, dan jasa penerbangan bergerak yang menunjang pelayanan lalu lintas penerbangan serta sistem lain yang mengolah atau menampilkan penerbangan. data panduan lalu lintas dan kondisi cuaca pada penerbangan. ATIS (Automatic Terminal Information Service) merupakan alat yang digunakan untuk memberikan informasi seperti cuaca, landasan aktif, dan informasi lain yang dibutuhkan pilot pada saat lepas landas atau mendaratkan pesawat. Informasi ini disiarkan dan dikirimkan setiap saat untuk mengurangi kesibukan komunikasi di radio penerbangan. Manurung, AP, Saragih, Y., & Adzilla, WN (2021). Dalam pelaksanaan kegiatan On the Job Training (OJT) yang kedua di LPPNPI Cabang Palembang terdapat beberapa permasalahan yang peneliti hadapi, salah satunya permasalahan yang dikemukakan peneliti yaitu pesawat tidak menerima siaran informasi cuaca dari peralatan ATIS karena sistem server PC mengalami kesalahan. Metode yang diterapkan dalam penelitian ini adalah kualitatif, dengan fokus pada studi kasus yang mencakup kegiatan proses penelitian. Tujuan utama dari penelitian ini adalah untuk menganalisis langkah-langkah yang dilakukan pada saat perbaikan peralatan ATIS, sehingga peralatan tersebut dapat memberikan informasi siaran cuaca kepada pilot secara normal kembali.
A theoretical study of the regioselectivity of the reaction of six-membered and five-membered nitrones with a series of substituted alkenes
Authors: Messaoudı Boulanouar
Published: May 2024

The experimentally observed regioselectivity of a series of alkenes reactions with some nitrones has been thoroughly investigated theoretically using density functional theory (DFT) B3lyp/6-31G(d) level of theory. Both Fukui and Parr indices have been calculated to explain and show the most reactive sites. The electrostatic surface potential has also been studied and analyzed in order to show the positive and negative regions responsible of the possible interaction between the two studied reactants. The theoretical results are in good agreement with the experimental findings.
In-silico design, molecular docking, molecular dynamic simulations, Molecular mechanics with generalised Born and surface area solvation study, and pharmacokinetic prediction of novel diclofenac as anti-inflammatory compounds
Authors: Mohammed Mazen , Amjed Adnan Abdulmohaimen
Published: May 2024

The prostaglandins inside inflamed tissues are produced by cyclooxygenase-2 (COX-2), making it an important target for improving anti-inflammatory medications over a long period. Adverse effects have been related to the traditional usage of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of inflammation, mainly centered around gastrointestinal (GI) complications. The current research involves the creation of a virtual library of innovative molecules showing similar drug properties via a structure-based drug design. A library that includes five novel derivatives of Diclofenac was designed. Subsequently, molecular docking through the Glide module and determining the binding free energy implementing the Prime-MMGBSA module by the Schrödinger software package was used to identify compounds that showed marked specificity towards the COX-2 isoform. In addition, the ligands are subject to evaluation of their drug-like properties and ADMET (absorption, distribution, metabolism, excretion, and toxicity) characteristics using the QikProp module. Finally, molecular dynamics simulation has been calculated for the best molecule. The docking results indicated that all compounds own a predictive capability for specific binding to the COX-2 enzyme compared to the standard drug with a docking score range from -10.07 to -10.66 Kcal/mole, thus potentially overcoming the limitations imposed previously by the drugs currently used in clinical use. The ADMET analysis of the virtually active compounds demonstrated an acceptable drug-like profile and desirable pharmacokinetics properties. MM/GBSA calculation revealed that all the suggested compounds exhibited favorable free binding energies (-49.150 to - 60.185 Kcal/mole), indicating their strong potential to fit well into the COX-2 receptor. Finally, the MD simulation study revealed that compound 1 had perfect alignment with COX-2 receptor. The findings indicated that the compounds possess a predictive capability for specific binding to the COX-2 enzyme, thus potentially surmounting the restrictions imposed by the drugs currently employed in clinical use.
Desing and In Silico Validation of Vitamin B5 and Its Derivatives As A Potential Target Against Cyclophilin A (CyPA)
Authors: Tabassum S Jamal Sayeedha , Predhanekar Mohamed Imran , T. K. Shabeer , Kubaib Attar , Meeran I Salım
Published: May 2024

The title molecule (N-(2,4-dihydroxy-3,3-dimethylbutyryl)b-alanine), DDBBA and its derivatives were selected for theoretical investigations viz geometry optimization, ADME profiling, binding affinity using quantum-mechanical calculations and modelling simulation tools. Geometry optimization by Gaussian 09 program revealed the stability and electrophilic nature of the investigated molecules. In order to depict the charge density distributions that may be related to biological activity, the contour maps of HOMO-LUMO as well as the associated chemical descriptors such as chemical potential (µ), electronegativity (χ), electrophilicity (ω), hardness (η) and softness (σ) were explored. Utilizing molecular docking, the antiviral, antibacterial, and anticancer activities was examined. The docked molecules showed strong propensity for binding to 2HQ6 cancer protein active sites. Vit B5-CH=CF2 and VitB5-CCl3 showed lowest binding energies (-5.861 and -5.478 kcal/mol) and low inhibition constant values (1.43 M). Studies on the (NBO) natural bond orbital, the Mulliken population, and the Fukui function were all analyzed. Further, the interactions between the derivatives and other molecules were studied using Hirshfeld surface analysis.
Theoretical Study of Khellin Derivatives as Corrosion Inhibitors Based on Density Functional Theory (DFT)
Authors: Marni Lidia Gusfi , Emriadi Emriadi , Imelda Imelda , Darajat Syukri , Khoiriah Khoiriah
Published: May 2024

Theoretical studies of Khellin in the presence of electron donor and electron with-drawing groups as a corrosion inhibitor are investigated using the B3LYP/6-31G (d, p) theory level with Gaussian software. This research focuses on the correlation between corrosion inhibition efficiency (EI%) and quantum chemical parameters such as EHOMO (Highest Occupied Molecular Orbital Energy), ELUMO (Lowest Unoccupied Molecular Orbital Energy), energy gap (∆E), dipole moment (µ), absolute hardness (η), absolute softness (σ), the absolute electronegativity (χ), the fractions of electrons transferred from the inhibitor molecule to the metallic atom (∆N), the electrophilicity index (ω), total energy (ET) and theoretical corrosion inhibition efficiency (EI %). The generated results show that the electron-donating groups increase the corrosion inhibition efficiency of Khellin in the sequence -NH2> -SH> -H> -NCH2> -NO2. The highest corrosion inhibition efficiency obtained about 98.40% proves that NH2-Khellin is the best corrosion inhibitor of iron.
Levantamento epidemiológico dos fatores de risco para o desenvolvimento de Diabetes Mellitus tipo 2 em estudantes da UFDPAR e sua correlação com as políticas de isolamento durante a pandemia da COVID-19
Authors: Correia Rafael Santos , Correia Thamiris Santos , Cruz Victor Trindade da , Lima João Cesar Fernandes , Santos Karina Rodrigues dos , Sousa Junior Severino Cavalcante de
Published: May 2024

A Diabetes Mellitus tipo 2 (DM2), é caracterizada pela dificuldade de atuação da insulina produzida pelo pâncreas. O aumento do seu risco está relacionado, principalmente, a hábitos não saudáveis e histórico familiar, que contrastam com o estilo de vida dos universitários, impulsionado pela carga de estudos elevada, estresse e alimentação irregular. Objetivo: Realizar uma análise epidemiológica dos fatores de risco ao desenvolvimento do DM2 em estudantes universitários da UFDPAR, correlacionando hábitos de vida durante a pandemia da COVID-19. Métodos: Estudo transversal quanti-qualitativo, realizado entre setembro de 2020 e junho de 2021 com graduandos da Universidade Federal do Delta do Parnaíba (UFDPar). Resultados: Dos 252 estudantes que participaram da pesquisa, observou-se que o sobrepeso e a obesidade, se fez presente em 25,4% dos alunos, já os sedentários foram maioria com 58,73% casos. Dos fatores de risco não evitáveis, 189 (75%) informaram história familiar de DM2, sendo que 58 (23,01%) em parentes próximos (pais, irmãos ou filhos). Dados que, associados a fatores ambientais, aumentam o risco de adoecimento por doenças crônicas. Com relação aos hábitos de vida durante o período de isolamento, 30% dos alunos passaram a comer mais alimentos industrializados e 58% relataram aumento de peso durante a pandemia, enquanto 32% informaram se alimentar de forma saudável. Conclusão: O sedentarismo, seguido do sobrepeso e alimentação inadequada surgem como os mais importantes fatores de predisposição a DM2 nos próximos 10 anos, agravados no período pandêmico devido aos atravessamentos psicossociais nele adquiridos.
Colestase neonatal: Uma abordagem desafiadora para pediatras diante dos principais diagnósticos diferenciais e tratamentos
Authors: Ferreira Renata Dias , Resende Leonardo Rodrigues
Published: May 2024

Os sinais clínicos da colestase neonatal como icterícia, acolia, colúria são facilmente perceptíveis. Porém, cabe ao pediatra a rápida diferenciação da causa da hiperbilirrubinemia colestática devido ao quadro de urgência pediátrica cujo diagnostico tardio pode ser potencialmente grave e letal. Este estudo objetivou identificar as principais causas de icterícia colestática em recém-nascidos e lactentes e como o pediatra pode realizar uma abordagem diagnostica precoce e iniciar tratamento. Por se tratar de um artigo de revisão integrativa propõe auxiliar de forma prática a abordagem dos principais diagnósticos diferenciais da icterícia colestática e terapêuticas disponíveis. As bases bibliográficas pesquisadas: Cocrhane, Embase, Medline e Pubmed. Os critérios de seleção foram artigos gratuitos na integra entre 2019 e 2024, em português, inglês ou espanhol, e presença de ao menos dois dos descritores. Assim, diante de um RN ictérico com mais de duas semanas de vida o pediatra deve solicitar dosagem de bilirrubinas, pois a colestase é sempre patológica com valores da forma direta superiores a 1,0mg/dl e as causas podem ser extra ou intra-hepática com um quadro desafiador de diagnósticos diferenciais. Na extra-hepática temos a atresia biliar cuja abordagem cirúrgica precoce leva a prognostico mais favorável. Por isso na investigação da colestase neonatal o pediatra precisa partir das doenças mais comuns priorizando as com tratamento cirúrgico devido risco de mortalidade. Sendo indispensável à investigação a realização da anamnese do binômio mãe-lactente, exame físico detalhado, avaliação das características das fezes, exames laboratoriais e de imagens, se necessário, biopsia com histopatológico e encaminhamento para especialista.
ESSENTIAL CHARACTERISTICS OF VOCATIONAL TRAINING IN EDUCATIONAL INSTITUTIONS MINISTRY OF INTERNAL AFFAIRS OF THE REPUBLIC OF BELARUS
Authors: Kriksin Andrej
Published: May 2024

The article examines the process of professional training of cadets studying in departmental educational institutions of the Ministry of Internal Affairs of the Republic of Belarus specializing in operational investigative activities. The key definitions of vocational training are presented from various points of view. The primary requirements for the professional training of future employees of operational units are disclosed. The main tasks of professional training are formulated, the implementation of which in the educational process will contribute to its effectiveness in the process of obtaining education by students. The author's definition of professional training and the main type of professional preparedness is given – service training with its fundamental components: special, tactical, fire, physical, drill, personal and professional safety of employees.
HISTORICAL AND LEGAL TRENDS OF CRIMINAL LIABILITY FOR THE DISORGANIZATION OF THE ACTIVITIES OF INSTITUTIONS THAT ENSURE THE ISOLATION OF CONVICTS (PRISONERS) FROM SOCIETY
Authors: Sych Konstantin
Published: May 2024

In Russia, one of the most common punishments throughout the entire period of existence has been punishments related to imprisonment and isolation from society. In the process of executing these punishments, problems may arise in their implementation. The key problem in this area is the improvement of measures to counter actions that disrupt the activities of correctional institutions. For several decades, Soviet legislation has been changing the concept of criminal liability for actions related to the disorganization of correctional institutions. The article examines the historical and legal trends in the development of criminal liability for violent acts against convicts (prisoners) and staff of institutions providing isolation from society at different historical stages. The work is based on the analysis of scientific literature and legislative acts that establish measures of responsibility for actions related to the disorganization of correctional institutions. The aim of the work was to raise the problem of criminal liability for the disorganization of correctional institutions for scientific discussion.
PENGOLAHAN DAN PENYAJIAN KUDAPAN MAKANAN SEHAT BERGIZI MOCHI UBI UNGU DI GKAI GADING SERPONG
Authors: Irawati Wahyu , Imelda Wuisan Pingkan , Chrismastianto Imanuel Adhitya Wulanata , Parhehean Munthe Ashiong , Laia Clement Khrisman , Manalu Damai Yanti
Published: May 2024

Pengabdian kepada Masyarakat (PkM) merupakan sarana melaksanakan misi Universitas Pelita Harapan yaitu berkontribusi untuk kemajuan ilmu pengetahuan dan kebudayaan berdasarkan wawasan Kristen Alkitabiah serta berpartisipasi dalam pengembangan individu dan masyarakat bagi kemuliaan Allah. Kegiatan PkM dilaksanakan di Gereja Kristen Alkitab Indonesia jalan Raya Kelapa Dua, Ruko Blitz, Blok A No. 28, Gading Serpong, Tangerang, Banten. Analisis kebutuhan berdasarkan angket menunjukkan bahwa jemaat belum memahami secara utuh bagaimana kudapan sehat dengan harga yang terjangkau. Kondisi ekonomi jemaat yang rendah membuat jemaat lebih memilih mengkonsumsi makanan murah dan tidak sehat tanpa memperhatikan kesehatan tubuh. Tujuan dilaksanakannya PkM adalah untuk 1) memberikan penyuluhan tentang kudapan bergizi, serta 2) melakukan pelatihan membuat mochi ubi ungu. PkM dilaksanakan pada tanggal 2 September 2023, dihadiri oleh 20 orang, disampaikan dengan metode ceramah demonstrasi. Hasil PkM berdasarkan hasil angket evaluasi dapat diketahui bahwa 77% responden menyatakan bahwa materi yang disampaikan sangat jelas, 55,6% setuju bahwa menonton youtube pembuatan mochi yang telah diberikan membantu untuk mempraktikkannya di rumah. Sebanyak 55,6 % sangat setuju bahwa mereka tertarik untuk mempraktikkannya di rumah bahkan ada satu jemaat yang telah mempraktekkannya dan menjual di sekolah. Sebanyak 44,4% responden sangat setuju bahwa pembuatan mochi ubi ungu mudah untuk dilakukan.
Kata kunci: Bergizi; kudapan; mochi; sehat; ubi ungu
Peningkatan Keterampilan Anggota Masyarakat Karang Taruna di Kelurahan Kebon Pala melalui Sosialisasi dan Workshop Desain Mural
Authors: Ulinata  , Dianty Grace Putri , Simatupang Sahala , Lourenza  , Baginda Amadea GL
Published: May 2024

Kegiatan Pengabdian kepada Masyarakat yang dijalankan Program Studi Arsitektur Fakultas Teknik UKI berjudul Green Action 34 Peningkatan Keterampilan Anggota Masyarakat Karang Taruna di Kelurahan Kebon Pala Melalui Sosialisasi dan Workshop Desain Mural. Kegiatan    ini merupakan lanjutan dari Kegiatan Pengabdian kepada Masyarakat sebelumnya yang bertujuan untuk menambah meningkatkan keterampilan anggota masyarakat karang taruna di Kelurahan Kebon Pala dengan memberikan pembekalan materi melalui sosialisasi dan workshop. Metodenya dengan mengundang narasumber untuk memberikan materi kepada para peserta kemudian mengadakan workshop dengan cara mempraktikkan langsung bagaimana mengecat mural dengan memilih lokasi di Kantor Lurah Kebon Pala sebagai pilot project dalam kegiatan ini. Kegiatan Pengabdian kepada Masyarakat ini menyediakan sponsor cat Aviand Brands yang menyiapkan segala alat dan bahan kegiatan Mural di kegiatan mural ini. Peserta akan diberikan dana untuk membeli cat dan kuas agar dapat melakukan kegiatan workshop sehingga hasilnya memuaskan. Hasilnya menunjukkan desain mural dapat diselesaikan dengan baik dan memperoleh hasil yang memuaskan.
Penerapan Disain Alternatif Pengembangan Rumah Adat Suku Dayak Tomun di Kabupaten Lamandau Provinsi Kalimantan Tengah: Penambahan Tempat Mandi-Cuci-dan Kakus (MCK)
Authors: Rilatupa James , Septiady Yophie
Published: May 2024

Suku Dayak Tomun yang tinggal di rumah adat, yang terkait dengan masalah MCK (mandi, cuci, dan kakus). Setelah inventarisasi dilakukan, kemudian dipelajari beberapa aspek, baik aspek potensial maupun aspek yang menghambat, dengan memperhatikan faktor lingkungan, termasuk   keberadaan sumber daya alam sekitarnya. Aspek potensial yang dipelajari adalah kesiapan dan penerimaan suku Dayak Tomun dalam memahami estetika dan kesehatan, terkait dengan kegiatan MCK yang ada di sekitar rumah mereka.  Aspek yang menghambat adalah kurangnya fasilitas maupun pengetahuan mengenai estetika dan kesehatan. Pada penataan denah yang baru perlu melengkapi kelayakan pakai fungsi ruang MCK, sarana sanitasi, sumber air bersih yang jaraknya jauh dari sungai. Usulan pengembangan rancangan rumah adat ini, tentunya mempertimbangkan standar luas serta sirkulasi aktivitas ruang didalam rumah dengan aktivitas di ruang luar menghasilkan pola ruang yang lebih bersifat pribadi, semi publik, dan publik. Penggunaan bahan bangunan non organik (baja dan beton) pada perbaikan rumah adat menjadikan keberadaan fisik bangunannya lebih baik. Sementara itu, dengan adanya tanda dan tata budaya adat yang mengalami penurunan makna, maka hal ini dapat dihindari dengan upaya pelestarian, bila Dinas Perumahan dan Pemukiman, serta Dinas Pariwisata membuat kebijakan atau regulasi untuk mempertahankan rancangan rumah adat agar tetap eksis ditengah pesatnya produk material modern sebagai bahan bangunan.
The Art of Translation: Methods to Deal with the Cultural Connotations of Flower and Plant Names in the Chu Ci
Authors: Yang  Yichen
Published: May 2024

The Chu ci, the earliest anthology of Chinese romantic poetry by Qu Yuan and other poets, contains a large number of flower and plant names which have both referential and symbolic meanings. These meanings are so difficult to identify and determine today as to bring about great trouble in understanding and representing the names in translation. This article briefly explores the double meaning of some flower and plant names in the Li sao, the most important poem in the anthology,
Hedonik Açlık Durumunun Besinlere Karşı Duyulan İstek ve Beslenme Alışkanlıkları ile İlişkisi
Authors: Özçalkap İçöz Rümeysa , Sönmez Aleyna , Atar Aslıhan , Batar Nazlı , Nas Sevil
Published: May 2024

Amaç: Bu çalışmada, üniversite öğrencilerinin besin alımlarının hedonik açlıkla olan ilişkisinin araştırılması amaçlanmıştır.
Gereç ve Yöntemler: Kesitsel, tanımlayıcı tipte olan bu çalışma Şubat- Mayıs 2022 tarihleri arasında bir vakıf üniversitesinin sağlık bilimleri fakültesinde öğrenim gören gönüllü katılımcılar ile yürütülmüştür. Örneklem büyüklüğü G*Power 3.1.9.7 programı ile etki büyüklüğü 0,25 hata oranı 0,05 ve yüzde 95 güçle 197 kişi olarak belirlenmiştir. Çalışmanın örneklemini çalışmaya katılmayı kabul eden 199 öğrenci oluşturmuştur. Katılımcıların demografik bilgileri ve beslenme alışkanlıkları genel bilgi formu ile hedonik açlık durumu ise besin gücü ölçeği (BGÖ) ile çevrimiçi olarak sorgulanmıştır. Beslenme alışkanlıkları BGÖ puanı ile ilişkilendirilmiştir.
Bulgular: Erkek cinsiyette kadın cinsiyetine göre BGÖ puanı daha yüksek bulunmuştur. (p
Gebelerde Toxoplazma Tarayalım mı? Literatür Değerlendirmesi Eşliğinde Beş Yıllık Gözlem
Authors: Gültekin Ceren , Kayabaşı Eda , Yıldırım Esma , Öksüz Şükrü
Published: May 2024

Amaç: Toksoplazmoz, Toksoplazma gondii’ nin neden olduğu, dünyanın her yerinde sorun olmaya devam eden bir hastalıktır. Sağlıklı bir erişkinde asemptomatik seyredebilir. Gebelikte geçirilen enfeksiyon; ölü doğum, fetal abortus veya gelişme geriliğine yol açmaktadır. Hastalık bebekte körlük, sağırlık veya ağır nörolojik sekellere sebep olabilmektedir. Bu çalışmada hastanemizin kadın doğum polikliniklerine başvuran gebelerde T. gondii seroprevalansının retrospektif olarak araştırılması ve literatürün gözden geçirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Çalışmamızda, hastanemizin kadın doğum polikliniklerine Ocak 2015-Aralık 2019 tarihleri arasında başvuran 112 adet gebe kadının anti-Toxoplazma IgG ve anti-Toxoplazma IgM sonuçları retrospektif olarak değerlendirildi.
Bulgular: Laboratuvarımıza 2015 yılında 32 (%29), 2016 yılında 32 (%29), 2017 yılında 23 (%20), 2018 yılında 18 (%16), 2019 yılında 7 (%6) hastadan örnek gönderildiği saptanmıştır. Anti Toksoplazma IgM pozitifliği sadece iki (%2) hastada, anti-Toksoplazma IgG pozitifliği ise 22 (%20) hastada belirlenmiştir. IgM pozitifliği saptanan iki hasta da aynı zamanda IgG pozitifliği de mevcuttu.
Sonuç: TC Sağlık Bakanlığının geniş gebe popülasyonlarında toksoplazmozun taranması ile ilgili yapılacak çalışmaları desteklemesi, çıkacak verilerin diğer çalışmalarla birlikte değerlendirilerek ulusal bir programın oluşmasına öncülük etmesinin gerekli olduğunu, bu program oluşana kadarki süreçte doğru bir taramanın yapılmasının ilgili kurum ve hekimler tarafından uygulanmasının akılcı bir yaklaşım olduğunu düşünmekteyiz.
Slow World Cinemas' Rhizomatic Flux in Carlos Reygadas's Japón
Authors: Chen Hui-Han
Published: May 2024

Adopting Gilles Deleuze and Felix Guattari's formulations of the rhizome, this article will examine a dynamic that lies between the film Japón's (Carlos Reygadas, 2002) vernacular specificities, European modernist aesthetics and cosmopolitan spectatorship. The article aims to reveal that Japón, along with other contemporary slow films from around the world, has the potential to reify a deterritorialising and reterritorialising encounter that rethinks a Eurocentric genealogical reading of world cinema and challenges a capitalist code of filmmaking.
A Deleuzian Dialogue between Leibniz and Ruyer: Monads, Absolute Survey and Life
Authors: Movahedi Hamed
Published: May 2024

In The Fold, Deleuze regards Raymond Ruyer as the most recent of Leibniz's great disciples. This claim is not self-evident, since Ruyer often criticises Leibniz and stresses the divergence of his theory from Leibniz's monadological metaphysics. Therefore, while Ruyer does not seem to regard himself as indebted to Leibniz, and as his psychobiology is not always reconcilable with Leibniz's philosophy, it is necessary to explore what is at stake in Deleuze's recognition of Ruyer as a Leibnizian thinker. This essay foregrounds the tacit intertwining between Leibniz and Ruyer, which can, on the one hand, contribute to Leibniz's scholarship and uncover the contemporaneity of his thought, and on the other hand, expose certain revealing Ruyerian moments in Deleuze's immanent philosophy.
The Utilization of Ternate Oral Tradition for The Identification of Potential Disasters
Authors: Subuh Rahma Do , Rauf Ramis , Maricar Farida , Ulya Afriani
Published: May 2024

Oral traditions, as an integral part of a society's belief system, not only serve as a guide for society in daily life, such as interactions between members of society and other people, and even with nature or the environment, but they also serve as recorders of history and culture, including natural events. This paper aims to describe the oral traditions of Ternate to identify potential natural disasters that hit Ternate City in particular and North Maluku in general. Therefore, the author uses the theory of myth function to embody the main research problem. The approach used in this paper is semiotics, especially in interpreting natural disasters that occurred in the past through codes contained in oral stories or legends. The research results show that the people of Ternate can only explain a few natural events in the past. Then, it is ontologically digested into myth to symbolise the cosmic-mystical realm of thought. Apart from that, the results of this reflection are related to cause-and-effect events, give rise to rules of behaviour, and become local intellectual ideals. However, records of natural phenomena or past events in myths or legends can, in theory, be linked to the truth and thus make cycles of disaster predictable. On the other hand, in a formal educational setting, this legend can be used to teach about mitigation. Legends about the mysterious origins of certain lakes are thought to include aspects of disaster or mitigation in Ternate.
Antara Ritual dan Pengetahuan Lokal: Strategi Mitigasi Erupsi Gunung Gamalama Perspektif Orang Ternate
Authors: Amin Safrudin , Aco Dewi Apriani , Cobobi M. Guntur
Published: May 2024

This research explores the disaster mitigation strategies for the eruption of Mount Gamalama from the perspective of the Ternate community. Using a qualitative ethnographic approach, it reveals how rituals and local knowledge are crucial aspects of mitigation strategy. It was found that the Ternate community integrates traditional rituals with the observation of natural signs as an early warning system. This shows a synergy between spiritual beliefs and practical knowledge in facing disaster risks. The article provides insights into the importance of maintaining local knowledge as part of an effective disaster mitigation strategy.