bluuebunny/crossref_metadata_2025 huggingface dataset:
Problems of interethnic relations and their reflection in the course of history
Authors: Fazliev Aivaz Minnegosmanovich , Brodovskaya Lyudmila Nikolaevna , Buravleva Vera Viktorovna , Galimzyanova Liliya Rifhatovna
Published: December 2020

The basis of the concept of humanitarization in education lies in the orientation of education towards solving problems in the field of modern civilization and culture. The problem of comprehensive consideration of the ethnic dimension of Russian society is among the fundamental problems that determine the strategy for the development of national education. The humanitarization in education is seen in the fact that through the sphere of education, a person can feel his or her ethnic, cultural, and historical uniqueness simultaneously with the realization of their belonging to world history. The concept of the humanitarization in education serves as the basis for building a multicultural educational environment, in the conditions of which the formation of multicultural thinking takes place, reflecting globalist trends. The paper analyses the functions of multicultural education: philosophical and cultural, ethical and humanistic, educational and reflexive, personal and developing in the context of the author's concept of humanitarization.
The artistic embodiment of the image of kazan in the works of modern russian and tatar poets
Authors: Galimullina Alfia Foatovna , Skvortsov Artem Eduardovich , Nurgali Kadisha Rustembekovna , Ibragimov Marsel Ildarovich
Published: December 2020

The article defines the functional role of key images, mythologemes and the means of artistic expression in the work of Russian and Tatar poets, which makes it possible to create an artistic image of. Kazan is also a legendary city with its own heroic past, it is also a cultural center, a university city, Kazan is also a city of meetings, and a city of spiritual communication. Renat Kharis metaphorically called "Kazan is a book" in the poem "Amirkhan Yeniki". This definition of the Tatar poet contains all aspects of the theme of Kazan image artistic embodiment because it fancifully combines images of poets of different times, melodies of composers, historical figures, legendary and mythological images (Shurale, nixie, etc.). The study results reflected in the article open up the prospects for the study of other universals in the poetry of the authors and other modern poets and can also be used for further study of local urban texts of Russian, Tatar and foreign literature.
Arbitration agreements in the foreign economic activity of russian companies
Authors: Lukin Yuri Mikhailovich , Vasiliev Arthur Robertovich , Shakiryanov Rafail Valievich
Published: December 2020

The article assesses the potential risks associated with the problem of recognizing the arbitration clause as inconsistent or invalid. The main scientific research method used in this article is the comparative legal method, which makes it possible to most accurately determine the common and different features in the approaches of different jurisdictions. This article discusses the main conditions and essential circumstances requiring attention when working with contracts in the foreign economic activity in terms of validity of the arbitration agreements. In order to achieve the goal set in the article, we analyzed: the legislation of the Russian Federation on international commercial arbitration, the UNISTRAL rules, the Convention on the Recognition and Enforcement of Foreign Arbitral Awards (1958), the international arbitration rules, the judicial practice related to the recognition and enforcement of arbitral awards. As a result of analysis, the article provides provisions aimed at increasing the efficiency of conclusion of such arbitration clauses in the foreign economic activity of Russian companies.
Three-in –One Live-In Program: Building University Students’ Soft Skills
Authors: Hartanto Yenny
Published: December 2020

This study aimed to answer the following questions: “what are the dominant soft-skills owned by the students of Business English study program”; “what are the most difficult soft-skills for the students during the implementation of three-in-one live-in program?”. This study used a qualitative descriptive survey approach. Moreover, the data analysis used content analysis techniques. Source of data of this study were 21 university students whose majoring in Business English study program from batch 2016 1nd 2017. The findings were that dominant soft skills was adaptation (average score was 3.9), while discipline and communication were the two most difficult soft-skills. (average score was 3.7 for each). This paper contributes to the implementation of soft skills within the higher education program called 3-in-1 live-in by directly involving students and the lecturers in the field continually.
Badiou’s Platonic gesture and the self-determination of philosophy
Authors: Chernyak Natalia A.
Published: December 2020

The article analyzes the philosophical concept of A. Badiou: the problem of reactualization of the Platonic gesture, i. e., the constitution of philosophy as an independent universal doctrine based on the harmonious unity of scientific ideas, art, politics and love. The attempt to construct a new ontology on mathematical grounds (“math”) is evaluated.
HOW TO EXPLAIN THAT CHANGES IN ELDERLIES
DEPRESSION LEVEL ARE UNIFORMLY DISTRIBUTED
Authors: Acosta Griselda , Smith Eric D. , Kreinovich Vladik
Published: December 2020

Changes in the elderlies depression level result from a large number of small independent factors. Such situations are ubiquitous in applications. In most such cases, due to the Central Limit Theorem, the corresponding distribution is close to Gaussian. For the changes in the elderlies depression level, however, the empirical distribution is far from Gaussian: it is uniform. In this paper, we provide a possible explanation for the emergence of the uniform distribution.
AUTOISOMETRIES AND AUTOSIMILARITIES OF LIE ALGEBRA 𝒜(1) ⊕ ℛ2
Authors: Podoksenov M. N. , Chernykh V. V.
Published: December 2020

We consider four-dimensional Lie algebra 𝒜(1) ⊕ ℛ2

endowed with

Lorentzian scalar product. We find all the one-parameter groups of isometries and

similarities, which are simultaneously automorphisms of Lie algebra, and also we find

the conditions of existence of such one-parameter group. Conditions of existence are

associated with the location of ideals with respect to isotropic cone.
ESSENTIAL SPECTRA OF ORDINARY DIFFERENTIAL OPERATORS II.
STABILITY OF SPECTRA
Authors: Erovenko V. A.
Published: December 2020

The article contains precise formulas for finding of the essential spectra

that are revolted with asymptotically constants on infinity in coefficients with use of

rather compact and rather small indignations on infinity in Lebesgue spaces of 𝐿

𝑝

.

These formulas are new analogs of the classical theorem of Weyl.
ON A SINGULARITY OF THE CAUCHY INTEGRAL OVER A CLOSED CONTOUR
Authors: Gorelov D. N.
Published: December 2020

A study is made of the parametric singularity of the Cauchy integral that arises when the sides of a closed loop come together. Formulas are obtained that relate the values of the Cauchy integral on different sides of an extremely narrow contour
About the Stokes law applicability
Authors: Nasyrov V. V. , Nasyrova M. G.
Published: December 2020

We find the correction coefficient for the Stokes law that permit to use this formula in case of a spherical body in a tube with the glycerol. An interpolation formula for the correction coefficient for a motion with low-Reynolds-number is obtained.
Localization and finding solutions of trinomial algebraic equations
Authors: Trubnikov Yu. V. , Chernyavsky M. M.
Published: December 2020

The article proposes a new simple method for localizing and determining the number of real solutions for an arbitrary trinomial algebraic equation with real coefficients. In detail, with illustrations, an analysis is made of all types of equations under study. For each type, conditions for the existence of multiple roots are obtained and exact analytical formulas for calculating them are given. For trinomial equations with a multiple root, it is shown that all other roots can be expressed through a multiple with the required accuracy.
Algorithm for recognizing text commands for constructing an arbitrary form of data input
Authors: Tumentcev E. A. , Meleshenko T. V.
Published: December 2020

The article proposes a solution to the problem of processing requests recorded in Russian to building data entry forms. Lexeme and syntactic analyzes stages request with examples are described. In the end of article, there is link to working project and repository with source code in Kotlin language.
Comparative analysis of stability criteria for polynomials
Authors: Chernyavsky M. M.
Published: December 2020

The article provides a comparative analysis of two stability criteria for polynomials. They do not require obtaining any information about the roots, but allow us to judge stability directly by the coefficients of the polynomial. On specific numerical examples, the features of their application are considered. The article also provides symbolic expressions of the relationship between the coefficients of sixth and fourth degree polynomials for cases where there is a linear or definite nonlinear relationship between the roots of these polynomials. In these cases, an algebraic equation of the sixth degree can be solved in radicals.
Teaching foreign languages: modern problems & their solutions (the second international conference to commemorate E.N. Solovova as a way to reflect current trends in secondary and higher education)
Authors: Konobeev A. V. , Khitrova I. V.
Published: December 2020

.
Transformation of the Latino image in Western culture (based on the analysis of American mass media)
Authors: Golousova E. S.
Published: December 2020

With rapid development of Latino communities and their members’s active involvement in the US social and political life the attitudes toward Latinos (Hispanics) have changed, both from the outside and the inside. The Latino people themselves came to realize their self-identification and, consecutively, the portrayal of Latinos in the media has been altered. In this paper the author argues, that the range of Latino stereotypes has become wider today and that the model that used to work decades ago in picturing Latino migrants is no longer relevant. Thus, the main goal of the study is to mark out and describe the changes that have occurred in the US media regarding the images of ‘Latinos’ (/Latinas). Comparative analysis is the key method in addition to the content analysis of media publications. The empirical basis consists of 80 publications, including digital media footage, published in 2016-2020 (both in English and Spanish languages) – such as the New York Times, The Time, The Washington Post, El Opinion, etc. These newspapers and magazines are considered to be highly influential as they set the agenda, shape the opinion and affect public consciousness. The material of the study also comprises 20 TV episodes related to the coverage of Hispanic issues in the USA. Having analyzed the media content related to the Latino issue (mainstream media, online sources, TV footage), the author comes to a conclusion that the number of roles that are attributed to the Latinos/Latinas has increased significantly and the today’s narrative to a larger degree is aligned with the changes occurring in real life of the Latino community.
Die psychiatrische Begutachtung von Kindern mit «abnormen Reaktionen» in der Zürcher Kinderbeobachtungs station Brüschhalde 1957 bis 1972
Authors: Galle Sara , Neuhaus Emmanuel , Künzle Lena , Lis Daniel , Ritzmann Iris
Published: December 2020

Der Beitrag setzt sich mit der psychiatrischen Beurteilung der Persönlichkeit im Zusammenhang mit der Fremdplatzierung von Kindern auseinander. Im Zentrum steht die Begutachtung zweier Kinder, die 1957 beziehungsweise 1972 von ihren Vormunden in die kinderpsychiatrische Beobachtungsstation Brüschhalde im Kanton Zürich eingewiesen wurden. Die Autorinnen und Autoren zeigen auf, wie Persönlichkeit im stationären Kontext konzeptualisiert, erfasst und bewertet wurde. Bei den beiden ausserehelich geborenen Kindern diagnostizierten die begutachtenden Ärztinnen und Ärzte, wie bei den meisten Kindern in der Brüschhalde zu jener Zeit, «abnorme», genauer «neurotische Reaktionen», die durch «ungünstige Milieuverhältnisse» ausgelöst worden waren und zu Entwicklungsstörungen führten.

Das Persönlichkeitskonzept der Kinderpsychiatrie stellte ein Entwicklungskonzept dar, das nicht nur die individuelle Entfaltung, sondern auch die gesellschaftliche Assimilation zum Ziel hatte. Die wichtigste Voraussetzung für eine «normale» Persönlichkeitsentwicklung des Kindes war und blieb ein «geordnetes, harmonisches Familienleben». Massgeblich für die Fremdplatzierung war nicht die Diagnose, sondern die familiäre Konstellation und die Persönlichkeit der Eltern, insbesondere der Mütter.
Pemphigus vulgaris: a rare auto-immune skin disease
Authors: Pet Nikhil Chandra Hanumanth Rao , Govula Sindhuja , Racherla Shweta , Raju Kodipelly Ramana
Published: December 2020

Background:

Pemphigus vulgaris (PV) is a rare autoimmune chronic blistering skin disease of type II hypersensitivity reaction.

Case Presentation:

The authors present a case of a 42-year-old male with the chief complaint of crusted plaques on face, chest, and scalp for 3 months associated with itching. On investigation, direct immunofluorescence showed immunoglobulin G antibodies. The patient was prescribed antibiotics, anti-inflammatory agents etc., but they did not show any efect. So, the physicians opted for pulse therapy.

Conclusion:

PV is a rare chronic ulceration of the mucosa where crusted plaques and blisters are seen. This condition can be efectively resolved using glucocorticoids and immunosuppressant. If untreated, this may lead to the death of the patient.
KARAKTERISTIK KLINIS PASIEN KEJANG DEMAM YANG DIRAWAT DI RUMAH SAKIT BAPTIS BATU
Authors: Susanti Yurika Elizabeth , Wahyudi Teguh
Published: December 2020

Pendahuluan: Kejang demam adalah jenis kejang tersering yang ditemukan pada pasien anak. Kejang demam dialami pada anak usia 6 bulan – 5 tahun disertai dengan peningkatan suhu tubuh. Penelitian ini bertujuan untuk menggambarkan karakteristik demografis dan klinis kejang demam pada anak. 

Metode: Desain penelitian adalah potong lintang, dilakukan pada 41 pasien kejang demam yang dirawat inap di Rumah Sakit Baptis Batu periode Januari 2017 – Oktober 2018. Data rekam medis dikumpulkan dan karakteristik klinik pasien digambarkan dalam bentuk tabel.

Hasil: Kejang demam lebih banyak diderita oleh anak laki-laki (61%), sebagian besar berusia 1 sampai 2 tahun (46,3%). Kejang umum (97,6%) merupakan jenis kejang yang sering ditemukan dengan durasi <15 menit (95,1%). Pasien kejang demam lebih banyak yang mengalami satu kali episode kejang (73,2%) dengan jenis kejang demam sederhana (70,7%). Suhu tubuh anak-anak mencapai ≥38⁰C (68,3%) dengan jumlah leukosit yang normal (63,4%).

Simpulan: Demam pada anak dengan usia <2 tahun, terutama dengan jenis kelamin laki-laki berpotensi menimbulkan kejang demam.
Tear replacement therapy for newly diagnosed glaucoma
Authors:   JSCB FGBUZ UOMTS FMBA of Russia, Astrakhan, Ramazanova L.S. , Yazykova E.Y. ,   JSCB FGBUZ UOMTS FMBA of Russia, Astrakhan, Napylova O.A. ,   JSCB FGBUZ UOMTS FMBA of Russia, Astrakhan, Shamratov R.Z. ,   JSCB FGBUZ UOMTS FMBA of Russia, Astrakhan
Published: December 2020

Цель. Оценка эффективности слезозаместительной терапии у пациентов с впервые выявленной первичной глаукомой. Материал и методы. В исследование было включено 20 пациентов с впервые выявленной ПОУГ I-II стадии, которым в качестве монотерапии были назначены простагландины или неселективные β-адреноблокаторы. Из них 12 мужчин и 8 женщин в возрасте от 60 до 70 лет. 30% пациентов имели сопутствующую глазную патологию (катаракта, хронические заболевания век и глазной поверхности), 50% – патологию системного характера (эндокринные заболевания, артериальная гипертензия, менопауза) с постоянной заместительной терапией, у 20% в анамнезе различного рода хирургические и лазерные операции глаз (ФЭК с ИОЛ, фокальная лазеркоагуляция сетчатки). После первичного обследования пациенты были разделены на 2 группы. Первой группе пациентов на ряду с гипотензивным препаратом был назначен лубрикант, восстанавливающий недостаток липидного и муцинового слоя по 1 капле 3 раза в день. Вторая группа пациентов не использовала слезозаменители. Результаты. Стандартное офтальмологическое обследование, позволило выявить синдром «сухого глаза» (ССГ) легкой степени. У 27% (5 чел.) ССГ был обусловлен хроническими заболеваниями придаточного аппарата глаза, дисфункцией мейбомиевых желез и у 73% (15 чел.) смешанного генеза (эндокринная патология, артериальная гипертензия , системный прием β-адреноблокаторов, гормональная заместительная терапия). Через 1 месяц на контрольном осмотре у всех пациентов 1-й группы, получавших слезозаменитель, уменьшились жалобы на чувство дискомфорта, жжения, затуманивания зрения в сравнении с группой, не получавшей слезозаменитель. Через 3 месяца субъективные жалобы у пациентов 1 группы практически отсутствовали, в то время как у пациентов 2-й группы отмечалось повышение степени выраженности жалоб. Выводы. Слезозаместительная терапия улучшает качество жизни пациентов, способствует приверженности лечению глаукомы, так как купирует жалобы и предотвращает осложнения, связанные с синдромом ССГ. Синдромом сухого глаза у пациентов с глаукомой индуцирован как входящими в состав гипотензивных капель консервантами, обладающими токсическим действием [4], так и наличием сопутствующей патологии глазного и системного характера. Ранее перенесенные хирургические операции переднего отрезка глаза предполагают нарушение стабильности слезной пленки.
On the issue of the accuracy of determining individually tolerated intraocular pressure in patients with primary open-angle glaucoma
Authors:   Volgograd branch of the NMITs IRTC Eye Microsurgery named after acad. S.N. Fedorov ", Balalin S.V. ,   Ministry of Health of the Russian Federation, Sargsyan A.S. ,   Volgograd branch of the NMITs IRTC Eye Microsurgery named after acad. S.N. Fedorov "Ministry of Health of the Russian Federation
Published: December 2020

Для достижения стабилизации глаукомного процесса у больных первичной открытоугольной глаукомой важно проводить патогенетически ориентированное лечение: снижение внутриглазного давления до индивидуально переносимого уровня или до «давления цели», уменьшение ишемии в структурах глаза, коррекция нарушенного метаболизма, использование цито- и нейропротекторов, лечение сопутствующих заболеваний [1]. Существуют различные методики определения индивидуально переносимого ВГД. Известна методика как 20-30-40% снижение от исходного уровня внутриглазного давления.
MODELING OF TURBULENT FLOWS IN MICROJET BURNERS BY USING CYLINDRICAL FLAME STABILIZERS WITH RECTANGULAR NICHE CAVITIES
Authors:   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine, Fialko Nataliia , Polozenko Nina ,   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine, Kutnyak Olha ,   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine, Tymoshchenko Oleksandra ,   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine, Klishch Andriy ,   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine, Regragui Aboubakr ,   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine, Hanzha Mark ,   Institute of Technical Thermophysics of the National Academy of Sciences of Ukraine
Published: December 2020

The results of computer modeling of the aerodynamics of burners with cylindrical flame stabilizers are presented. The data of a comparative analysis characteristics of current in the presence and absence of niche cavities on the side surfaces of the stabilizers are fetched.
MAIN ASPECTS OF APPLICATION OF LATENT-STRUCTURAL ANALYSIS DURING DESIGN TESTS
Authors:   Institute of Pharmacy Professionals Qualification Improvement Kharkiv National University of Pharmacy, Bahan Svitlana , Musyka Tamara ,   Institute of Pharmacy Professionals Qualification Improvement Kharkiv National University of Pharmacy
Published: December 2020

The paper proposes an approach to optimizing the design of tests during the study of pharmaceutical disciplines using latent-structural analysis, which allows to assess the validity and analysis of testing for testing.
STARTUPS IN THE IT FIELD. THEIR SIGNS AND STAGES, UKRAINIAN AND FOREIGN EXPERIENCE
Authors:   Banking University, Yarema Oleg , Tarasenko Pavlo ,   Banking University
Published: December 2020

The term "startup" was first used in Forbes magazines in August 1976 and Business Week in September 1977 to refer to companies with a brief history. The concept took hold in the 1990s and spread during the dot-com boom. The term "startup" has recently gained popularity, but it is often misunderstood and misinterpreted. Thousands of businesses are opened every year around the world, and only some of them are startups.
IMPROVEMENT OF INNOVATIVE ACTIVITY OF THE ENTERPRISE
Authors:   Sumy National Agrarian University, Stoyanets Nataliya , Aboyi Mathias Onuh ,   Sumy National Agrarian University
Published: December 2020

The article defines that for the successful implementation of an innovative project and the introduction of a new product into production it is necessary to use advanced technologies and modern software, which is an integral part of successful innovation by taking into account the life cycle of innovations. It is proposed to consider the general potential of the enterprise through its main components, namely: production and technological, scientific and technical, financial and economic, personnel and actual innovation potential. Base for the introduction of technological innovations LLC "ALLIANCE- PARTNER", which provides a wide range of support and consulting services, services in the employment market, tourism, insurance, translation and more. To form a model of innovative development of the enterprise, it is advisable to establish the following key aspects: the system of value creation through the model of cooperation with partners and suppliers; creating a value chain; technological platform; infrastructure, determine the cost of supply, the cost of activities for customers and for the enterprise as a whole. The system of factors of influence on formation of model of strategic innovative development of the enterprise is offered. The expediency of the cost of the complex of technological equipment, which is 6800.0 thousand UAH, is economically calculated. Given the fact that the company plans to receive funds under the program of socio-economic development of Sumy region, the evaluation of the effectiveness of the innovation project, the purchase of technological equipment, it is determined that the payback period of the project is 3 years 10 months. In terms of net present value (NPV), the project under study is profitable. The project profitability index (PI) meets the requirements for a positive decision on project implementation> 1.0. The internal rate of return of the project (IRR) also has a positive value of 22% because it exceeds the discount rate.
THE IMPACT OF DECENTRALIZATION ON THE DEVELOPMENT OF ENTREPRENEURSHIP IN UKRAINE
Authors:   University of Customs and Finance, Mishchenko Lyudmyla , Mishchenko Dmytro ,   University of Customs and Finance
Published: December 2020

The actualization of the results of financial decentralization in Ukraine as part of the reform of decentralization of power and the development of proposals for its improvement is explained by the fact that a clear division of functions, powers and financial resources between national and regional levels is the basis for the well-being of our citizens. opportunities for its sustainable socio- economic development on a democratic basis. It is noted that financial decentralization is a process of giving authority to mobilize revenues and expenditures of local governments in order to increase the effectiveness of the implementation of these powers and better management of community budgets. It is established that unlike traditional entrepreneurship, which focuses on profit generation, the purpose of social entrepreneurship is to create and accumulate social capital. Abroad, social enterprises operate successfully in the fields of education, the environment, human rights, poverty reduction and health care, and their development and dissemination is one way to improve the living conditions of citizens. A similar mission is entrusted to local governments, which allows us to consider the revival of social entrepreneurship as an important element in improving self-government policy. It is determined that in modern conditions social entrepreneurship is one of the tools to ensure the ability of the local community to provide its members with an appropriate level of education, culture, health, housing and communal services, social protection, etc., as well as plan and implement programs efficient use of available natural and human resources, investment and infrastructural support of territorial communities. Due to financial decentralization, local governments have received additional resources that can be used to create economic incentives to promote social entrepreneurship in small and medium-sized businesses at the community level.
THEORETICAL PRINCIPLES OF FORECASTING THE COST OF A SOFTWARE PRODUCT
Authors:   Professional College of Engineering and Management of NAU, Rodionov Pavlo , Ploskonos Anna ,   Professional College of Engineering and Management of NAU, Gavrutenko Lesya ,   Professional College of Engineering and Management of NAU
Published: December 2020

The paper analyzes the factors that affect the amount of effort required to create a mobile application and its cost. It is established that the main factors of influence are the design of the application, its functionality, the type of mobile platform, the availability and level of testing and support, as well as the individual characteristics of the developer. Based on the analysis of information sources, the main methods and approaches to forecasting the cost of software products are identified, which include the COCOMO model, Price-to-win method, expert evaluation, algorithmic methods and the method of analogies. It is proposed to consider the method of analogies as a tool that allows you to make predictions about the cost of resources required for the successful implementation of IT projects based on the experience of similar projects. It is proved that the advantages of this method are the simplicity of its implementation and the clarity of the results obtained, which follows from the practical orientation of this tool. Among the limitations of the method of analogy is the mandatory need for reliable data relating to similar projects, as well as the difficulty of taking into account unspecified indicators. Taking into account the mentioned limitations of the method of analogies and on the basis of the analysis of scientific sources the possible directions of its optimization are determined. Thus, among the ways to improve the effectiveness of this method are those aimed at optimizing the project selection process, the data for which are used as a basis for forecasting. Attempts to improve the method of analogies by including parameters that were previously ignored by this technique seem promising. This in turn can lead to an expansion of the scope of the method of analogies and increase the accuracy of forecasts. As prospects for further research, the need to continue research in the field of optimization of the method of analogies with the subsequent practical verification of theoretical positions on the data of real projects.
FEATURES OF APPROACHES TO ASSESSING ECONOMIC SECURITY OF REGIONS
Authors:   Dolishniy Institute of Regional Research of NAS of Ukraine, Tymchyshyn Yuliya
Published: December 2020

Approaches to assessing the economic security of the region used in a particular interweaving are analyzed, in which the basis is often a functional (or complex) approach, which involves the allocation of functional areas (components or aspects) of economic security, each of which reflects a particular aspect of the region's economic system. The basic rules of formation of the set of primary indicators for assessing the economic security of the region are considered: limited number of primary indicators of the model, quantitative (or quasi- quantitative) nature of indicators, information capacity of the indicator, determining the value of the indicator by direct measurement or direct algorithms. An indicator approach is highlighted, through which the economic security of the region is assessed by comparing (absolute or relative) the actual values of indicators with their indicators and the appropriate treatment of the identified deviations. The indicator approach looks very attractive when describing the sequence of techniques, procedures, calculation operations and algorithms used. The main problematic issues in the use of indicator approach are formulated: plurality of sets of indicators, unambiguous limit or threshold values of indicators, lack of rules for selection of indicators, limited application of a systematic approach in forming a set of indicators, setting values of indicators. The use of interval indicators of economic security of the region is revealed, which provide an opportunity to identify some dangerous zone, within which its state is gradually changing; The economic security of the region may be in this danger zone for some time, the duration of which depends on the influence of a number of factors. It is noted that in determining the number of indices for assessing the economic security of the region, two approaches are possible: a small number of indices, each of which evaluates a significant number of aspects of economic security of the region; a significant number of indices, each of which assesses a small number of aspects of the region's economic security.
THE INTERNET IN A CIVIL SERVANT`S LIFE
Authors:   Sumy State University, Telizhenko Liudmyla , Murach Dmytro ,   Sumy State University
Published: December 2020

The article is dedicated to the analysis of negative aspects of the use of social media in civil service and the substantiation of the necessity of legal regulation of civil servants’ conduct in the web space. It is mentioned that the Internet virtual space has become another new place of life of a contemporary human and a civil servant as well. Like in physical and social space, a human is able to act, be active, influence the situation and other people while equally depending on their reverse influence. This requires greater responsibility from civil servants for the content of their posts and the information shared by them on social media as well as understanding that contacts established there shall still obey the law and the rules of virtual life. Emphasis is put upon the necessity of civil servants’ considering of the specific nature of social media that can constitute certain dangers. It becomes possible to invade their professional and private life, their personal data; they may be blackmailed, put under political pressure and so forth. Focus is placed on the absence of proper regulation of civil servants’ ethical conduct in the web space by the state. At the same time, the article shows international experience in the matter of regulation of a civil servant’s socialization in the web space. The authors examine foreign legislative acts regulating the particular question of the interaction of a civil servant’s real and virtual life. This leads to the conclusion about the advisability of the introduction of special recommendations or an ethical code which would regulate the rules of conducting civil servants’ web life. It is also emphasized that the implementation of the corresponding rules of British legislation into Ukraine would become a significant step to resolving civil servants’ web problems.
Melt Polycondensation for the Synthesis of Polyester Amides using Kneader Reactor Technology
Authors: Blanchard Lucien , Rader Chris , Vanoli Ennio , Marti Roger
Published: December 2020

In this work, we discuss the process development and scale-up of the melt polycondensation of polyester amides from a laboratory scale to kg-scale in a kneader reactor. We identified and optimized the most important critical parameters and produced kg-quantities of polyester amides
with Mn up to 25'000 g/mol and reproducible thermal and mechanical properties. The special kneader reactor allows safe and efficient scale-up of polymerisation reactions at high temperature and viscous melts due to good mixing and efficient mass transfer.
Neuroimaging with Radiopharmaceuticals Targeting the Glutamatergic System
Authors: Mu Linjing , Krämer Stefanie D. , Ahmed Hazem , Gruber Stefan , Geistlich Susanne , Schibli Roger , Ametamey Simon M.
Published: December 2020

Radiopharmacy at ETH has worked on the development of novel PET tracers for neuro-, cardiac- and tumor imaging for many years. In this paper, our efforts on targeting the glutamatergic system of the metabotropic glutamate receptor subtype 5 (mGluR5) and the ionotropic N-methyl-D-aspartate
(NMDA) receptor are summarized. We briefly described the principles of positron emission tomography (PET) tracer development for the central nervous system (CNS) and the radiolabeling methods used in our laboratory. To assess the radioligands, results of in vitro autoradiography, biodistribution,
and metabolite studies as well as PET imaging data are discussed. Furthermore, key PET parameters for kinetic modeling and quantification methods are provided. Two mGluR5 PET tracers, [11C]ABP688 and [18F]PSS232, were translated in our GMP labs and evaluated in human
subjects. The newly developed GluN2B PET tracer [11C]Me-NB1 is currently being investigated in a first-in-human PET study and several F-18 labeled tracers are being evaluated in non-human primates in which the first-in-class will be translated for human studies.
The Metamorphosis of Radionuclide Production and Development at Paul Scherrer Institute
Authors: Grundler P. V. , Eichler R. , Talip Z. , Schubiger P. A. , Schibli R. , Van der Meulen N. P.
Published: December 2020

Radionuclide production and development has a long history at the Paul Scherrer Institute (PSI) and dates back to the founding times of its forerunner institutions: the Federal Institute for Reactor Research and the Swiss Institute for Nuclear Research. The facilities used for this
purpose have evolved substantially over the last five decades. Many radiometals in use today, as radiopharmaceuticals, are for the diagnosis and treatment of disease, with the most popular means of detection being Positron Emission Tomography. These positron emitters are easily produced at
low proton energies using medical cyclotrons, however, developments at these facilities are lacking. Currently, the fixed 72 MeV proton beam at PSI is degraded at IP2 irradiation station to provide the desired energy to irradiate targets to produce the likes of 44Sc, 43Sc
and 64Cu as a proof of principle, which are of great interest to the nuclear medicine community. This development work can then be implemented at facilities containing medical cyclotrons. A history of the development of radionuclides at PSI, along with current development and projects
with partner institutions, is described.
Radioanalytics – An Indispensable Tool for Radiological and Nuclear Safety
Authors: Schumann Dorothea , Heule Martin
Published: December 2020

The exact knowledge on the inventory of a radioactive sample is a precondition to act appropriately in terms of nuclear safety. Radioanalytical methods aimed to determine the radionuclide content of activated material play therefore a central role regarding safe operation of nuclear
installations, protection of personnel, inhabitants and environment as well as for the design and construction of new facilities. The article gives an overview on the broad variety of analysis and measurement methods, describes necessary chemical separation procedures and explains the impact
for nuclear safety assessment in the field of radioanalytics at the Paul Scherrer Institut Villigen, Switzerland. It addresses both the safe routine operation of nuclear installations, which can be a challenge to our radiometric capabilities and refers to selected radioanalytical research
projects.
TorsionNet: A Deep Neural Network to Rapidly Predict Small Molecule Torsion Energy Profiles with the Accuracy of Quantum Mechanics
Authors: Rai Brajesh , Sresht Vishnu , Yang Qingyi , Unwalla Rayomond J. , Tu Meihua , Mathiowetz Alan M. , Bakken Gregory A.
Published: December 2020

TorsionNet: A Deep Neural Network to Rapidly Predict Small Molecule Torsion Energy Profiles with the Accuracy of Quantum Mechanics Brajesh K. Rai*,1, Vishnu Sresht1, Qingyi Yang2, Ray Unwalla2, Meihua Tu2, Alan M. Mathiowetz2, and Gregory A. Bakken3 1Simulation and Modeling Sciences and 2Medicine Design, Pfizer Worldwide Research Development and Medical, 610 Main Street, Cambridge, Massachusetts 02139, United States 3Digital, Pfizer, Eastern Point Road, Groton, Connecticut 06340, United States ABSTRACT Fast and accurate assessment of small molecule dihedral energetics is crucial for molecular design and optimization in medicinal chemistry. Yet, accurate prediction of torsion energy profiles remains a challenging task as current molecular mechanics methods are limited by insufficient coverage of druglike chemical space and accurate quantum mechanical (QM) methods are too expensive. To address this limitation, we introduce TorsionNet, a deep neural network (DNN) model specifically developed to predict small molecule torsion energy profiles with QM-level accuracy. We applied active learning to identify nearly 50k fragments (with elements H, C, N, O, F, S, and Cl) that maximized the coverage of our corporate library and leveraged massively parallel cloud computing resources to perform DFT torsion scan of these fragments, generating a training dataset of 1.2 million DFT energies. By training TorsionNet on this dataset, we obtain a model that can rapidly predict the torsion energy profile of typical druglike fragments with DFT-level accuracy. Importantly, our method also provides a direct estimate of the uncertainty in the predicted profiles without any additional calculations. In this report, we show that TorsionNet can reliably identify the preferred dihedral geometries observed in crystal structures. We also present practical applications of TorsionNet that demonstrate how consideration of DNN-based strain energy leads to substantial improvement in existing lead discovery and design workflows. A benchmark dataset (TorsionNet500) comprising 500 chemically diverse fragments with DFT torsion profiles (12k DFT-optimized geometries and energies) has been created and is made freely available.
Evaluación de los niveles de iluminación en empresas de explotación de rocas fosfóricas para la elaboración de productos agroindustriales en el departamento del Huila
Authors: Victoria Bonilla Reinaldo Alfredo , Sandoval Castro Natalia , Gamboa Suárez Ramiro
Published: December 2020

El presente estudio tiene como propósito evaluar los niveles de iluminación en las áreas de trabajo de empresas mineras dedicadas a la explotación de rocas fosfóricas para la elaboración de productos agroindustriales en el departamento del Huila. Para dicho estudio, se realizarán mediciones con un luxómetro, considerando la ubicación del terreno donde se encuentran las fábricas, la luz natural y la artificial. Estas mediciones se ejecutarán con el fin de evaluar las condiciones de iluminación que se encuentran en ese sector para determinar recomendaciones y así conseguir mejores resultados en las instalaciones, atendiendo a criterios de cantidad, calidad de luz y eficiencia energética. Posteriormente, en referencia a la normativa colombiana, estos resultados se analizarán, y con ello se determinará si las empresas cumplen con lo establecido para salvaguardar la seguridad y la salud de sus colaboradores.
IMPLEMENTATION OF THE PRIVATE PUBLIC PARTNERSHIP (PPP) POLICY IN THE SUPPLY OF DRINKING WATER IN TANGERANG DISTRICT
Authors: Setiawan Slamet
Published: December 2020

This study describes the implementation of the Public Private Partnership (KPS) policy between the Tangerang Regency Government and PT. Aetra Air Tangerang in providing drinking water for the people of Tangerang Regency. This study aims to determine how the success of policy implementation using Edward III's theory as a measure of success. The key informant in this study is the Regional Secretary of Tangerang Regency as the person in charge and implementer of the policy. This research was conducted in a descriptive method with a qualitative approach. The data collection techniques in this study are by observation, interviews and desk study or literature study. The results of this study indicate that the implementation of the Public Private Partnership (KPS) policy between the Tangerang Regency Government and PT. Aetra Air Tangerang in the provision of drinking water, has been running quite well, especially in terms of resources, disposition and bureaucratic structure. problems and constraints are found in the communication factor where the transmission, clarity and consistency of policies have encountered many problems and it is necessary to find the most appropriate solution, so that policy implementation can be maximized and achieve policy objectives optimally.
KNOWLEDGE MANAGEMENT DAN PENGARUHNYA DALAM PENGAMBILAN KEPUTUSAN PADA BADAN PEMBENTUKAN PERATURAN DAERAH DEWAN PERWAKILAN RAKYAT DAERAH KABUPATEN TAKALAR
Authors: Said Muh. , Fatmawati Fatmawati , Hakim Lukman
Published: December 2020

Changes in the environment experienced by organizations require organizations to make adjustments to answer all future challenges. The strength that must be possessed by the organization is to realize the concrete concept that becomes a tool to make changes. One of them is knowledge management, because knowledge management is an organizational activity that manages knowledge as an asset, wherein various strategies there is the right distribution of knowledge to the right people in a fast time until they interact with each other from various knowledge and apply it in daily work for performance improvement. Knowledge Management integration in the decision-making process can be interpreted as a structured and systematic process in acquiring, distributing, and utilizing knowledge to support the decision-making process. The position of knowledge management in decision making is between two poles of knowledge, namely tacit knowledge on the one hand and the utilization of explicit knowledge in decision making on the other. Explicit knowledge emphasizes the implicit role of knowledge management in influencing actors involved in decision making. Research design using quantitative methods. The instruments used in this study were questionnaires. The results showed that the implementation of Knowledge management has a positive effect on decision making in the Regional Development Agency of Takalar regency.
Evaluation of different weed management practices in dry direct seeded spring rice at Baniyani, Jhapa, Nepal
Authors: Poudel Rakshya , Marahatta Santosh , Kandel Santosh , Puri Purnima
Published: December 2020

A field experiment was conducted during the spring season of 2020 to evaluate the different weed management practices in dry directed seeded spring rice under Prime Minister Agriculture Modernization Project (PMAMP) super zone at Baniyani, Jhapa. The experiment was laid out in randomized complete block design (RCBD) with seven weed management related treatments and three replications. The treatments consisted of pre-emergence application of Pretilachlor, pre-emergence application of Pendimethalin, pre-emergence application of Pretilachlor fb post-emergence butachlor pre-emergence application of Pendimethalin fb post-emergence Bispyribac Na, Sesbania co-culture along with pre-emergence application of Pendimethalin along with two control treatments (weedy free and weedy check). The rice variety Hardinath-1 was used in the experiment. Data regarding the weed flora, weed density, weed dry weight, growth, yield attributes and yield were recorded and analyzed. The highest number of effective tillers per m2 (371.51) and number of grains per panicle (145.43) were obtained in Pendimethalin treated plot and were statistically as par with Sesbania co-culture + Pendimethalin (363.44 m-2 and 140.54 respectively). Higher and statistically similar grain yield was observed in Sesbania co- culture + Pendimethalin (4870kg ha-1) and Pendimethalin treated plots (4780 kg ha-1). The experiment concluded that there was reduction in yield by 66.78 percent due to presence of weed as compared to weed free. Pre-emergence application of Pendimethalin was most beneficial in terms of gross returns, net returns and B:C ratio compared to other weed management practices and hence was most economical.
Effects of COVID-19 induced pandemic on the production, trade, and income of smallholder vegetable growers in Kathmandu Valley, Nepal
Authors: Gadal Nirmal , Neupane Basanta , Shrestha Rudra B. , Baniya Susan
Published: December 2020

This study assessed the effects of the COVID-19 pandemic on production, trade and income of smallholder vegetables growers in the Kathmandu valley, Nepal. We made a scenario-based situation analysis of pre-COVID (January to March 2020) and COVID-19 pandemic induced lockdown (April to June 2020) situations. The study used a descriptive research design and employed multistage sampling techniques. One hundred forty-five vegetable growers were surveyed and six focus group discussions were carried out between May to July 2020 in the three municipalities- Chandragiri, Mahalaxmi and Changunarayan of Kathmandu, Lalitpur and Bhaktapur districts respectively. The study showed that the income of smallholders' vegetable growers was decreased by 66.1 percent due to an increase in input price (16.9 percent), a decrease in output price (62.67 percent), and low farm productivity (9.3 percent) in comparison with the pre-COVID period. This paper has figured out the impact pathways that caused the income decline of vegetable growers. The primary constraints to smallholder producers were the absence of local aggregators followed by transportation barriers, limited market opening hours, and mobility obstruction and changed consumers' behavior due to lockdown. Majority of the farmers adjusted to the situations by selling their products at lower prices, free distribution to the local inhabitants, and composting and dumping the surpluses. The study concluded that this kind of analysis is necessary to develop resilient supply chains and extend appropriate support to the smallholder farmers who are critical actor to the supply chains.
Evaluation of lures for monitoring the population of thrips and whitefly in the major horticultural crops in Nepal
Authors: Soti Ankit
Published: December 2020

Field experiment was conducted to evaluate the effectiveness of whitefly and thrips lure in yellow stick traps in major horticultural crops in IRD station, Dahachowk & Nala, Nepal. This experiment was carried out from June to September, 2019.   Six major horticultural crops have been selected. In each cropping area yellow sticky traps with whitefly lure, yellow sticky traps with thrips lure and yellow sticky traps only has been setup. Weekly data of insects has been recorded with the help of hand lens.  In yellow sticky traps wide range of insects whitefly, thrips, leaf miner, winged aphids, housefly, fungus gnats, fruit fly, Tuta absoluta whereas, some beneficial insects as bee, wasp, beetle has been monitored. Analysis of variance was carried out as per the procedures given in R-STATC statistical computer package for the paired two T- tests. Thrips lure has shown significant result against thrips whereas whitefly lure doesn’t show any notable effects against whitefly over yellow sticky traps. Further research on such lure will be valuable for the farmers in different agro-climatic locations of the country for validation.