bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Monolithic and Sandwich Panels Subjected To Non-Uniform Thickness-Wise Boundary Conditions
Authors: Vescovini Riccardo , Dozio Lorenzo
Published: November 2018

The analysis of monolithic and sandwich plates is illustrated for those cases where the boundary conditions are not uniform along the thickness direction, and run at a given position along the thickness direction. For instance, a sandwich plate constrained at the bottom or top face can be considered. The approach relies upon a sublaminate formulation,which is applied here in the context of a Ritz-based approach. Due to the possibility of dividing the structure into smaller portions, viz. the sublaminates, the constraints can be applied at any given location, providing a high degree of flexibility in modeling the boundary conditions. Penalty functions and Lagrange multipliers are introduced for this scope. Results are presented for free-vibration and bending problems. The close matching with highly refined finite element analyses reveals the accuracy of the proposed formulation in determining the vibration frequencies, as well as the internal stress distribution. Reference results are provided for future benchmarking purposes.
Triple Consciousness: The Reimagination of Black Female Identities in Contemporary American Culture
Authors: Welang Nahum
Published: November 2018

My article underscores the intermediate existence of black American women between race and gender by stressing the role white patriarchy and black hypermasculinity play in the marginalisation of black female voices and the prioritisation of white women’s interests within and beyond mainstream feminist spaces. In order to legitimise this intermediate existence of black women, my article develops the triple consciousness theory (TCT). Inspired by W.E.B. Du Bois’ concept of double consciousness, TCT argues that black women view themselves through three lenses and not two: America, blackness and womanhood. Black feminists, TCT affirms, are able to reimagine misguided narratives of black womanhood in contemporary American culture by unpacking the complexity of this threefold consciousness. In Bad Feminist, Roxane Gay strives for the inclusion of pluralist voices in the mainstream feminist movement and in Lemonade, Beyonce uses Afrofuturist tropes, reappropriation and gothic imagery to exorcise the generational pain of betrayal by black men and white women. With Insecure, Issa Rae radicalises feminist theory by critiquing archetypes attached to black womanhood and in Marvel’s Black Panther, not only do black women possess the unprecedented agency to shape their own identities on their own terms, there is also an existential reconnection with their past.
The Politics of Unification in a Fragmented World: Metapopulism and the Precariat
Authors: Hauser Michael
Published: November 2018

Neoliberal capitalism intensified the social fragmentation, which resulted in the upswing of heterogeneous communities without a unifying meta-language that was liberal universalism of citizenship. Our society shows “paralogical” traits and paralogy reverberates in the new populist policy I call metapopulism (Trump, Putin, etc.)-witness their inconsistencies. Metapopulism establishes unifying principles as a substitute of liberal universalism. These are allegory and the Real. An allegorical signifier (“patriotism” etc.), which is separated from the signified (the meaning), is a common representation of heterogeneous communities and simultaneously maintains their paralogy. The Real appears as the signifier that is excluded from “correct” liberal discourse and promises to enhance the experience of a system’s failures by attributing a social meaning to it (sublimation). These principles work on the condition that their promises are permanently thwarted and deferred, which is their spectrality. However, another type of unification may be feasible. It is a unifying discourse and practise that is grounded in a specific position of the “precariat” as the hegemonical class as formed by neoliberal capitalism (the Lukacsian concept). Here, a unification is borne by the praxis of sublimation.
The strong Fatou property of risk measures
Authors: Chen Shengzhong , Gao Niushan , Xanthos Foivos
Published: November 2018

In this paper, we explore several Fatou-type properties of risk measures. The paper continues to reveal that the strong Fatou property,whichwas introduced in [19], seems to be most suitable to ensure nice dual representations of risk measures. Our main result asserts that every quasiconvex law-invariant functional on a rearrangement invariant space X with the strong Fatou property is (X, L1) lower semicontinuous and that the converse is true on a wide range of rearrangement invariant spaces. We also study inf-convolutions of law-invariant or surplus-invariant risk measures that preserve the (strong) Fatou property.
Complex method for calculating total serum calcium concentration
Authors: Eremenko Natalia N. , Shikh Eugenia V. , Serebrova Svetlana Y.
Published: November 2018

Background

Calcium drugs are analogs of endogenous substances. The baseline concentration of endogenous substances in the body and homeostasis mechanisms of regulation make the bioavailability and bioequivalence (BE) evaluation of these drugs very difficult. The aim of the study was to assess the pharmacokinetic parameters of calcium in the studies of comparative bioavailability combined with the assessment of homeostatic regulation mechanisms.

Methods

The study included 42 healthy male volunteers. We studied the composition of 1000 and 1200 mg of calcium, and 800 and 1000 IU of cholecalciferol. Blood sampling was carried out at 8 a.m. and 0.5, 1, 2, 3, 4, 6, 8 h after administering the drugs. Calcium pharmacokinetic parameters were measured: the area under the curve (AUC) “concentration-time”, and maximum concentration (Cmax) in volunteers. The excretion of calcium in urine in terms of creatinine clearance and parathyroid hormone (PTH) levels was assessed. The maximum excretion of calcium was converted to creatinine (calcium/creatinine). Enzyme-linked immunosorbent assay (ELISA) was used to determine the PTH and the o-cresolphthalein method to quantitatively measure the total calcium serum and urine.

Results

Results indicated that both the AUC and the excretion of calcium are comparable, and the differences are not statistically significant, p>0.05 (the ratio of calcium and creatinine in the urine maintained within physiological levels). The comparable dynamics of PTH concentration is an indirect measure of the amount of absorbed calcium.

Conclusions

The study demonstrates that, along with the standard way of calculating the area under the curve “concentration-time” (total calcium in serum), it is important to assess the calcium excretion in urine in terms of creatinine excretion, as well as focusing on the changes in the PTH levels in volunteers, which could be considered as a marker of the calcium level in the blood.
Estimating Case-Fatality Reduction from Randomized Screening Trials
Authors: Saha Sudipta , Liu Zhihui (Amy) , Saarela Olli
Published: November 2018

In randomized cancer screening trials where asymptomatic individuals are assigned to undergo a regimen of screening examinations or standard care, the primary objective typically is to estimate the effect of screening assignment on cancer-specific mortality by carrying out an ’intention-to-screen’ analysis. However, most of the participants in the trial will be cancer-free; only those developing a genuine cancer that is screening-detectable can potentially benefit from screening induced early treatments. Here we consider measuring the effect of early treatments in this partially latent subpopulation in terms of reduction in case fatality. To formalize the estimands and identifying assumptions in a causal modeling framework, we first define two measures, namely proportional and absolute case-fatality reduction, using potential outcomes notation. We re-derive an earlier proposed estimator for the former, and propose a new estimator for the latter motivated by the instrumental variable approach. The methods are illustrated using data from the US National Lung Screening Trial, with specific attention to estimation in the presence of censoring and competing risks.
Stressors and Stress Responses in Cystic Fibrosis
Authors: Bebok Zsuzsa , Fu Lianwu
Published: November 2018

Cystic fibrosis (CF) is a life-shortening, genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). The primary cause of CF is reduced CFTR-mediated chloride and bicarbonate transport, due to mutations in CFTR. However, inflammation and persistent infections influence clinical outcome. Cellular stress response pathways, such as the unfolded protein response (UPR) and the integrated stress response (ISR), referred to here as cellular stress response pathways (SRPs), contribute to the pathology of human disorders. Multiple studies have indicated activation of SRPs in CF tissues. We review our present understanding of how SRPs are activated in CF and their contribution to pathology. We conclude that reduced CFTR function in CF organs establishes a tissue environment in which internal or external insults activate SRPs. SRPs contribute to CF pathogenesis by reducing CFTR expression, enhancing inflammation with consequent tissue remodeling. Understanding the contribution of SRPs to CF pathogenesis is crucial even in the era of CFTR “modulators” that are designed to potentiate, correct or amplify CFTR function, since there is an urgent need for supportive treatments. Importantly, CF patients with established pathology could benefit from the targeted use of drugs that modulate SRPs to reduce the symptoms.
Rational design of an improved photo-activatable intein for the production of head-to-tail cyclized peptides
Authors: Böcker Jana K. , Dörner Wolfgang , Mootz Henning D.
Published: November 2018

Head-to-tail cyclization of genetically encoded peptides and proteins can be achieved with the split intein circular ligation of peptides and proteins (SICLOPPS) method by inserting the desired polypeptide between the C- and N-terminal fragments of a split intein. To prevent the intramolecular protein splicing reaction from spontaneously occurring upon folding of the intein domain, we have previously rendered this process light-dependent in a photo-controllable variant of the M86 intein, using genetically encoded ortho-nitrobenzyltyrosine at a structurally important position. Here, we report improvements on this photo-intein with regard to expression yields and rate of cyclic peptide formation. The temporally defined photo-activation of the purified stable intein precursor enabled a kinetic analysis that identified the final resolution of the branched intermediate as the rate-determining individual reaction of the three steps catalyzed by the intein. With this knowledge, we prepared an R143H mutant with a block F histidine residue. This histidine is conserved in most inteins and helps catalyze the third step of succinimide formation. The engineered intein formed the cyclic peptide product up to 3-fold faster within the first 15 min after irradiation, underlining the potential of protein splicing pathway engineering. The broader utility of the intein was also shown by formation of the 14-mer sunflower trypsin inhibitor 1.
A theoretical framework for using humor to reduce the effects of chronic stress on cognitive function in older adults: An integration of findings and methods from diverse areas of psychology
Authors: Mallya Sasha , Reed Maureen , Yang Lixia
Published: November 2018

This paper synthesizes the literature on cognitive aging, emotion regulation, and humor, to provide a theoretical framework for the utility of humor in promoting successful cognitive aging. Many older adults experience some degree of cognitive decline, which is associated with reductions in functional status, independence, and overall quality of life. These losses can result in considerable stress that is chronic in nature. The following discussion proposes humor as a technique that older adults may use to reduce stress and protect cognitive abilities. Humor here is described as a form of cognitive reappraisal, allowing older adults to reappraise daily stressors. Further, it is speculated that humor’s protective value is in the reduction of chronic activation of the physiological stress response systems, which in turn may protect functional integrity of the hippocampus and prefrontal cortex. Because older adults appear to have difficulty solving more complex jokes, we propose that low complexity, self-enhancing humor may be the most useful form of humor for older adults.
Neurotransmittergesteuerte Rezeptoren in neuem Licht: Optische Methoden zur Kontrolle physiologischer Funktion
Authors: Reiner Andreas
Published: November 2018

Neurotransmittergesteuerte Rezeptoren sind auf vielfältige Weise an der synaptischen Signalleitung und Modulation beteiligt. Am Beispiel der Glutamatrezeptoren wird schnell deutlich, dass diese Rezeptorfamilien eine enorme Diversität aufweisen und es daher eine große Herausforderung bleibt, die unterschiedlichen Funktionen nah miteinander verwandter Rezeptorsubtypen aufzuklären. Pharmakologische und genetische Methoden werden zunehmend durch optogenetische Ansätze ergänzt, welche es erlauben, das Rezeptorsignaling mit Licht zu manipulieren. Am Beispiel der Glutamatrezeptoren lege ich dar, wie kovalent verankerte photoschaltbare Liganden genutzt werden können, um einzelne Rezeptorsubtypen mit hoher räumlicher und zeitlicher Präzision in ausgewählten Zellen zu kontrollieren. Mit diesen und ähnlichen Techniken eröffnen sich neue, vielversprechende Möglichkeiten, die Funktion bestimmter Rezeptoren im Nervensystem zu untersuchen.
Interartery discordance in fetuses with growth restriction
Authors: Mackeen A. Dhanya , Ross John W. , Betz Alexandria , Feng Wen , Bringman Jay J. , Paglia Michael J.
Published: November 2018

OBJECTIVES: Our objectives were two-fold: 1) to determine the frequency of discordant umbilical artery Doppler systolic to diastolic (S/D) ratios in the individual umbilical arteries of growth-restricted fetuses and 2) to examine the impact of the frequency of discordance on clinical outcomes. METHODS: This was a prospective, observational study of growth-restricted fetuses. Doppler velocimetry was performed weekly and two S/D ratios were obtained for each fetal umbilical artery. Inter-artery discordance was defined as a difference in measurement categories (i.e., normal, elevated, absent, reversed) between the arteries. The number of abnormal measurements per visit was summed to 0-4 out of 4 values. A composite average number of abnormal Doppler measurements was calculated and fetuses were stratified based on degree of average number of abnormalities in increments of 25%: 0-<25%, 25-<50%, 50-<75%, and 75-100% abnormality. RESULTS: Of a total 241 fetuses (1762 visits), 110 (45.6%) had abnormal UAD flow and 189 (66%) demonstrated discordance. Abnormal values were noted in only one artery in 53% (n=151) of visits. Fetuses with any abnormal Doppler testing had smaller birthweights compared to fetuses with consistently normal testing (2485g vs 2623g, p <0.01); birthweight decreased as composite average of abnormal measurements increased (p = 0.03). CONCLUSION: The majority (66%) of fetuses with abnormal testing demonstrated UAD discordance. Up to 53% of fetuses could have been misdiagnosed if only one artery was tested. Fetuses with a higher frequency of Doppler abnormalities had lower birthweights. We propose obtaining two measurements from each umbilical artery in growth-restricted fetuses.
Risk related brain regions detection and individual risk classification with 3D image FPCA
Authors: Chen Ying , Härdle Wolfgang K. , He Qiang , Majer Piotr
Published: November 2018

Understanding how people make decisions from risky choices has attracted increasing attention of researchers in economics, psychology and neuroscience. While economists try to evaluate individual’s risk preference through mathematical modeling, neuroscientists answer the question by exploring the neural activities of the brain. We propose a model-free method, 3-dimensional image functional principal component analysis (3DIF), to provide a connection between active risk related brain region detection and individual’s risk preference. The 3DIF methodology is directly applicable to 3-dimensional image data without artificial vectorization or mapping and simultaneously guarantees the contiguity of risk related brain regions rather than discrete voxels. Simulation study evidences an accurate and reasonable region detection using the 3DIF method. In real data analysis, five important risk related brain regions are detected, including parietal cortex (PC), ventrolateral prefrontal cortex (VLPFC), lateral orbifrontal cortex (lOFC), anterior insula (aINS) and dorsolateral prefrontal cortex (DLPFC), while the alternative methods only identify limited risk related regions. Moreover, the 3DIF method is useful for extraction of subjective specific signature scores that carry explanatory power for individual’s risk attitude. In particular, the 3DIF method perfectly classifies both strongly and weakly risk averse subjects for in-sample analysis. In out-of-sample experiment, it achieves 73 -88  overall accuracy, among which 90 -100  strongly risk averse subjects and 49 -71  weakly risk averse subjects are correctly classified with leave-k-out cross validations.
Die Stundentexte zu Seiten der Nut auf der Innenseite des Deckels des inneren Sarges Milano E 0.9.40147 eines Peftjau(em)auuiaset
Authors: Graefe Erhart
Published: November 2018

Publication of the inner face of the cover of the inner coffin Milano E 0.9.40147 belonging to an untitled . It contains short awakening-texts for the sake of Osiris (e. g., the owner of the coffin) arranged as the 12 hours of day and night. The hours are represented as kneeling goddesses in adoration bearing a sun-disk on their heads for the day or a star for the night. The texts of both sides are of different types, the hours of the day being called “embodiment” of Horus and those of the night “doors”. The composition is the same as on the sarcophagi of the Napatan kings Anlamani and Aspelta. To date the version from the Milano coffin has only been dealt with en passant.
Classifying the Duat
Authors: Zago Silvia
Published: November 2018

The notion of Duat plays a major role in ancient Egyptian funerary beliefs. Yet, a single definition of this notion is impossible to achieve, as it underwent a process of evolution over thousands of years without ever designating just one unambiguous place at a time. In this context, an approach based on cognitive linguistics and on the significance of the determinatives accompanying the word Duat can be exploited to shed more light on this elusive concept. The focus will be here on the Pyramid Texts and the Coffin Texts as well as the intermediary phase of transmission of the funerary literature during the period between the end of the Old Kingdom and the beginning of the Middle Kingdom.
Address practice as social action: European perspectives. By Catrin Norrby and Camilla Wide (eds.)
Authors: de Oliveira Sandi Michele
Published: November 2018

Address practice as social action: European perspectivesCatrin Norrby and Camilla Wide (eds) (2015)New York: Palgrave Macmillan. Pp. 151 + xiISBN: 978-1-137-52992-3 (eBook)
Investigation of the films based on the uronate polysaccharides by the method of differential scanning calorimetry
Authors: Коndratjuk N. , Pyvovarov Ye. , Stepanova Т. , Matsuk Yu.
Published: November 2018

In this paper, the problem of studying of the films properties on the basis of uronate polysaccharides (sodium alginate and pectin low-esterified amidated), created on the principle of ionotropic gelation with the participation of calcium ions, has being considered. The purpose of the study is to determine the patterns of films formation based on the composition of the uronate polysaccharides, to determine their properties when heated and conditions of destruction or combustion. The thermophysical properties of the films in the temperature range 20–500°C were controlled by the method of differential scanning calorimetry in the dynamic mode. The temperature at which the loss of external and internal moisture is occurring have been determined. The temperatures when films are subjected to destruction have been founded. Thus, the mass loss of samples was noted in the following temperature ranges: 52–100°С and 40–100°С; the maximum moisture loss was noted at 83 and 85°C for specimens with a total concentration of uronate polysaccharides 2% and 3% respectively. Maximum external moisture losses were 6% and 9%; intra-linked moisture – 28.5 and 29% respectively. Complete disintegration of polymers occurs after 300 and 310°C for specimens with a total concentration of uronate polysaccharides 2% and 3% respectively. The investigation of the destraction temperatures of the above systems allows us to predict the principle of heat treatment of semi-finished products contained in films, created on the basis of the reaction of ionotropic gelation of polysaccharides and calcium ions.
Determination of some chemical and quality parameters of changes in turkish Sari Ulak monocultivar extra virgin olive oil during 12 months of storage
Authors: Ghanbari Shend E. , Sivri Ozay D. , Ozkaya M . T. , Ustunelc N. F.
Published: November 2018

In this study Turkish monocultivar extra virgin olive oil (EVOO) “Sarı Ulak” was extracted by using the Mobile Olive Oil Processing Unit (TEM Oliomio 500-2GV, Italy). Changes in minor and major components and quality characteristics, free fatty acid content, peroxide value and UV absorbance value, were surveyed during a year’s storage period. “Sarı Ulak” olive oil samples were classified as EVOO according to the trade standards of the International Olive Council (IOC) based on free fatty acid, peroxide value, K232 and ΔK values up to the eighth month of the storage period. The results have shown that color values of EVOO changed from green to yellow slowly while UV absorbance values changed during storing. Total polyphenol content of extra virgin olive oil decreased from 205.17 ppm to 144.29 ppm during a year’s storage. Luteolin was the most abundant phenolic compound, and its concentration changed from 184.33 ppm to 115.06 ppm. Apigenin concentration was differed from 2.67 to 1.06 ppm during storing. The initial level of α-tocopherol contents was 184.51 ppm, it decreased to 147 ppm at the end of storage time. After 12 months of storing, about 20 % of α-tocopherol content was destroyed. The amounts of phenolic and tocopherol isomers decreased during storage as expected.
Development of technological solutions for flour production with specified quality parameters
Authors: Zhygunov D. , Kovalova V. , Kovalov M. , Donets A.
Published: November 2018

Today, bakery and milling industry is actively developing, as well as other branches of food industry. This is due to the applying of new foreign trends to the technology and range of products of the Ukrainian market. In these conditions, the classic offering of flour is already inadequate. To meet the needs of modern bakeries, milling industry is facing a new challenge: production of flour grades with specified quality parameters.
The article considers the technological and baking properties of flour from all systems of the technological process of a flourmill with a capacity of 300 tons per day. Studies have shown that flour from first-quality systems is whiter by 15–20 units, is by 1.0–1.8% lower in ash, by 1–3% lower in protein, by 2–4% lower in gluten with more elastic properties, has a Falling Number higher by 80–110 s, a water absorption capacity lower by 1–5%, a damaged starch value lower by 1–3 UCD as compared to flour from systems of some other quality. Technological solutions are developed for producing a special flour grade by its selection and mixing from the streams of the 1st break system (B1/B2), 1st reduction system (C1/C2), 2nd sizing system (R2), and 1st vibratory bran finisher system (V1). It has been found that the developed grade of flour – patent superior grade flour – meets the requirements and has high baking performance. It has a gluten content higher by 2%, Falling Number lower by 20 s, and Starch Damage less by 2 UCD, as compared to patent high grade flour. This makes it possible to obtain bread larger in volume by 55 cm3, with smooth, even crust, elastic white crumb, and uniform porosity (80%). According to rheological characteristics determined with a Mixolab device, patent superior grade flour has a higher Water Absorption Index, a higher Viscosity Index, a lower Gluten+ Index, and a lower Amylase Index than patent high grade flour. The developed technological solutions for producing flour with specified quality parameters have been introduced at the flourmill with an equipment package, from the company Alapala (Turkey), with a capacity of 300 tons per day.
Obtaining and characteristic of the magnesium organic forms on the basis of products of bifidobacteria processing and their metabolites
Authors: Kapustian A. , Antipina O. , Budiak R.
Published: November 2018

The possibility of obtaining bioavailable mixed ligand chelate complexes of Magnesium has been considered. As bioligands, it is proposed to use the metabolites and products of enzymatic hydrolysis of the peptidoglycans of the cell walls of Bifidobacterium bifidum AC-1670. As ligands, fragments of peptidoglycans of cell walls of bifidobacteria, which have their own immunotropic effects, were used. Destruction of bacterial cells was done by ultrasound treatment with subsequent enzymatic hydrolysis with papain. It was found that the highest content of potential ligands for chelation was obtained by ultrasound treatment at a frequency of 35 kg for 600 seconds with subsequent enzymatic hydrolisys, which lasted for 180 minutes at a ratio of the enzyme: substrate 1:1. In this case, the accumulation of amino acids in the hydrolyzate was 11.35 mg/cm3, low molecular weight peptides - 7.54 mg/cm3. The liquid phase of the product of the disintegration of the bacterial mass is investigated for the presence of metabolites that can participate in the formation of chelating magnesium complexes. Qualitative composition and quantitative content of organic acids are determined. It is established that in the product of disinfection of bifidobacteria the following acids are present: acetic (445.5 mg/dm3), lactic (284.6 mg/dm3), benzoic (1.3 mg/dm3). It has been established that the obtained mixed ligand systems are effective chelating agents and bind magnesium in an amount of 14 mg/cm3. The method of IR spectroscopy has proved that this system is formed with the participation of polydentant ligands. Determination of the pH stability of the complex showed that in the range of pH values 4–7, the chelate system is stable, at pH 2 only 10% of the complex is stored, at a pH of 9 – 60%. The thermostability of the complex was investigated by the method of differential scanning calorimetry. It was established that the complex is stable in the temperature range of 20-122 ° С, and therefore can be used as a physiologically functional ingredient in the health foods, the technology of which involves high-temperature processing.
GENE POLYMORPHISM ANALYSIS OF CHEMOKINES, CHEMOKINE RECEPTORS, ACUTE PHASE PROTEINS, AND CD14 IN FEMALE OBESITY DEVELOPMENT
Authors: Kochetova O. V. , Akhmadishina L. Z. , Korytina G. F. , Victorova Т. V.
Published: November 2018

In the present study, we have investigated frequency of genotypes and functional alleles of genes encoding chemokines (CXCL12 rs1801157, CCL2 rs1024611), chemokine receptors (CCR5 del32, CX3CR1 rs3732378), acute phase proteins SAA rs1136743, and CD14 rs2569190 polymorphisms among Tatar obese or overweight women from the Republic of Bashkortostan.

The group of patients comprised unrelated women with obesity (BMI ≥ 30 kg/m2, n = 225), females with overweight (BMI 25.0-29.9 kg/m2, n = 184), and control group of women (n = 327) BMI < 25.0 kg/m2. Genotyping was performed by PCR-RFLP analysis. Patients and controls differed in such parameters as body weight (p = 0.00001), BMI level (p = 0.001) and fasting glucose level (p = 0.0001).

An association was revealed between obesity andAG-AAgenotypes (p = 0.007) andAallele (p = 0.003) of polymorphic locus rs3732378 ofCXCR1gene, as well asTTgenotype (p = 0.027) andTallele (p = 0.021) of polymorphic locus rs1136743 ofSAAgene. It has been shown that theAAgenotype of polymorphic locus rs3732378 of theCX3CR1gene is associated with increased body weight (p = 0.002) and elevated BMI (p = 0.018); theGGgenotype of polymorphic locus rs1024611 of theCCL2gene is associated with elevated fasting glucose level (p = 0.001).

As based on clinical and genetic data and using logistic regression, some statistically significant differences were revealed, which allow to predict development of obesity in Tatar women.
Ministros-técnicos e ministros-políticos nos governos do PSDB e do PT
Authors: Codato Adriano , Franz Paulo
Published: November 2018

Resumo Estudos sobre recrutamento ministerial têm identificado a presença tanto de políticos profissionais quanto de técnicos no gabinete ministerial brasileiro. Todavia, análises de carreira têm se restringido apenas aos técnicos, enquanto estudos sobre ministros políticos focam majoritariamente o critério partidário de recrutamento. Este artigo possui dois objetivos: demonstrar empiricamente as diferenças e semelhanças entre as carreiras dos ministros políticos e dos não políticos (“técnicos”) durante os governos do Partido da Social Democracia Brasileira (PSDB) e do Partido dos Trabalhadores (PT), entre 1995 e 2014; e explorar os principais aspectos relativos à profissionalização dos ministros políticos, a partir de suas experiências em cargos eletivos e de alto escalão de governos estaduais e municipais. Os resultados indicam que tanto políticos como não políticos possuem larga experiência profissional, inclusive administrativa, embora os não políticos possuam maior afinidade com a área ministerial para a qual foram nomeados. Por sua vez, ministros filiados ao partido do presidente possuem maior afinidade com a área de jurisdição ministerial quando comparados com os ministros filiados a partidos da base aliada. A despeito dessas nuanças, não foram constatadas diferenças significativas entre os governos peessedebistas e petistas quanto à expertise dos seus ministros.
Public investment, competitiveness and development: a study into Brazilian tourism destinations
Authors: Vieira Daniel Pires , Hoffmann Valmir Emil , Alberton Anete
Published: November 2018

Abstract This paper analyzes the efficiency of federal government funding for destination competitiveness and the relationship among destination competitiveness enhancement and local development. Destination competitiveness models provide the theoretical background. The research is exploratory and descriptive. We mapped the investments from Brazilian Ministry of Tourism in 65 destinations. Destination Competitiveness was measured with information from the Brazilian Competitiveness Model. Data were analyzed with data envelopment analysis and multiple regression analysis. Study findings demonstrate that competitiveness enhancement does not depend on the amount of funding, but on its strategic application according to destination development stage. Besides, competitiveness dimensions Marketing, Monitoring, and Cooperation are major drivers for local development.
Avaliação do desempenho das Unidades Pernambucanas de Atenção Especializada (Upae) tipo II, 2016
Authors: Silva Luciana Bezerra da , Costa Juliana Martins Barbosa da Silva , Duarte Monik Silva
Published: November 2018

RESUMO Avaliou-se o desempenho das Unidades Pernambucanas de Atenção Especializada (Upae) tipo II nos municípios de Caruaru, Garanhuns e Petrolina em 2016. As unidades têm recente implantação na rede de saúde e foram criadas como estratégia para expansão da média complexidade que historicamente se apresenta como um vazio assistencial no Estado. Utilizou-se o modelo Balanced Scorecard (BSC), que adota as perspectivas financeira, de processos internos, de aprendizado e crescimento, e do usuário. Para tanto, elaborou-se o modelo lógico das Upae, adaptou-se ao BSC e gerou-se a matriz de medidas e julgamento. Classificouse o desempenho em excelente (≥75%), satisfatório (74-50%), insatisfatório (49-25%) e crítico (<25%). Identificou-se melhor desempenho na Upae Petrolina (88,2%). Quanto às perspectivas, a do usuário mostrou o maior desempenho (100%), enquanto aprendizado e crescimento apresentou o menor desempenho (65%). Destaca-se que as Upae possuem ferramentas e insumos físicos, humanos e de equipamentos necessários à prestação de serviços aos usuários do Sistema Único de Saúde, necessitando aprimorar alguns indicadores financeiros, de processos internos e aprendizado e crescimento.
Controle social e avaliação de desempenho de sistemas de saúde em tempos de webcontrole
Authors: Carnut Leonardo , Narvai Paulo Capel
Published: November 2018

RESUMO Este ensaio teve como objetivo indagar sobre a forma como, no Brasil, o controle público (‘controle social’) está sendo feito, especialmente na contemporaneidade, quando a internet entra como um elemento a tornar ainda mais complexos os caminhos para o efetivo exercício do controle do desempenho das políticas de saúde. Para tanto, abordam-se as características do desempenho desse tipo de controle público nas ciências administrativas e sua influência nos processos de avaliação em saúde, a complexidade implicada na opção de tomar os ‘sistemas de saúde’ como ‘objetos’ da avaliação de desempenho e, ainda, a capacidade do sujeito contemporâneo de participar desse tipo de ‘controle social’ em sua forma virtual. Uma possibilidade sugerida para esta participação, sem necessariamente se institucionalizar, pode ter como ponto de partida a elaboração da opinião coletiva oriunda da captura e do processamento das percepções individuais disponibilizadas sobre os desempenhos, em todos os sítios eletrônicos na ‘web’.
REVASCULARIZAÇÃO MIOCÁRDICA: REFERÊNCIA E CONTRARREFERÊNCIA DO PACIENTE EM UMA INSTITUIÇÃO HOSPITALAR
Authors: Lanzoni Gabriela Marcellino de Melo , Koerich Cintia , Meirelles Betina Hörner Schlindwein , Erdmann Alacoque Lorenzini , Baggio Maria Aparecida , Higashi Giovana Dorneles Callegaro
Published: November 2018

RESUMO Objetivo: compreender o processo de referência e contrarreferência vivenciado pelo paciente com coronariopatia submetido à cirurgia de revascularização do miocárdio. Métodos: pesquisa qualitativa, ancorada na Teoria Fundamentada nos Dados. O cenário da pesquisa foi uma instituição hospitalar pública, referência em atendimento cardiovascular no Estado de Santa Catarina (Brasil). A coleta de dados ocorreu entre março de 2013 a junho de 2014, por meio de entrevista semiestruturada envolvendo 21 participantes, distribuídos em três grupos amostrais (pacientes, profissionais de saúde e profissionais gestores). Resultados: o processo de referência e contrarreferência aponta o fenômeno “Emergindo a alta complexidade como referência para a pessoa submetida à revascularização miocárdica diante da fragilidade da Atenção Primária à Saúde no acompanhamento e articulação com os demais níveis de atenção no Sistema Único de Saúde”, sustentado por cinco categorias. Conclusão: para que a referência aconteça há necessidade de consolidar o vínculo do paciente com coronariopatia com a atenção primária à saúde, uma vez que este encontra dificuldades no acompanhamento da sua condição na rede pública. Na contrarreferência evidenciou-se a desarticulação entre os serviços de atenção à saúde, a qual afeta o cuidado à pessoa submetida à revascularização miocárdica na manutenção da sua qualidade de vida.
HOW SCAPHOID FRACTURES ARE TREATED IN BRAZIL
Authors: Nacif Gustavo Chaves , Pedro Fernando Moises Jose , Moraes Vinicius Ynoe de , Fernandes Marcela , Bellot João Carlos
Published: November 2018

ABSTRACT Objective: To verify how hand surgeons manage scaphoid fractures and their complications. Methods: Two hundred questionnaires were distributed during the 36th Brazilian Hand Surgery Congress (2016). Results: On suspicion of fracture without radiographic confirmation, 57% of surgeons request a CT or MRI scan, while 43% opt for immobilization and consecutive radiographs. In stable fractures the preference was for treatment with plaster cast. In fractures with no scaphoid waist displacement, 33% opt for percutaneous fixation. In displaced waist or proximal pole fractures, 66% and 99.4%, respectively, opted for surgical treatment. Most surgeons treat waist nonunion with a nonvascularized bone graft. When absorption at the site of nonunion is greater than 4 mm, 50% prefer to use iliac graft and screw fixation. In proximal pole nonunion, the Zaidemberg technique is preferred by 64%. More experienced surgeons are more likely to request tests in occult fractures (63.9% versus 47.6%; p=0.04), and tend to recommend surgery for distal third fractures more frequently (16.4% versus 4.7%; p=0.02). Conclusions: We have provided an overview of treatment preferences for scaphoid fractures. It should be noted that more experienced surgeons are more likely to request additional tests for occult fractures and to recommend surgical treatment of distal third fractures. Level of Evidence IV, Cross-sectional survey.
Análise do líquido cérebro-espinhal de três doenças do sistema nervoso central de cães
Authors: Polidoro Dakir N. , Santos Rosmarini P. , Aiello Graciane , Chaves Rafael O. , Ripplinger Angel , Wrzesinski Mathias R. , Schwab Marcelo L. , Mazzanti Alexandre
Published: November 2018

RESUMO: Foi realizado um estudo retrospectivo do líquido cérebro-espinhal de cães (LCE), atendidos pelo Serviço de Neurologia do Hospital Veterinário da Instituição, de 2004 a 2015, com o objetivo de analisar os resultados de cães com sinais neurológicos, comparar as alterações encontradas em dois locais de colheita no mesmo paciente e verificar se esse exame auxiliou o clínico em reforçar a suspeita clínica das principais doenças do sistema nervoso central. A pleocitose linfocítica esteve presente em 78,3% (29/37) das amostras de cães com cinomose e em 23,2% (10/43) de cães com DDIV. Houve dissociação albuminocitológica (DAC) em 73% (19/26) das amostras de cães com tumores IC e em 64,3% (9/14) de cães com tumores envolvendo a ME. Em cães com DDIV, houve significância estatística (p<0,05) entre o grau de disfunção neurológica e o total de células nucleadas (TCN) e total de proteínas (TP). Em 29 cães, houve a colheita do LCE da cisterna magna e da cisterna lombar e em 12 (41,4%) os resultados foram diferentes entre as duas amostras colhidas do mesmo cão, onde dois (6,9%) apresentaram alteração na amostra colhida cranial à lesão. Pode-se concluir que a pleocitose linfocítica foi a principal alteração encontrada no LCE de cães com cinomose e DDIV e DAC nas neoplasias, IC e ME, cães acometidos pela DDIV apresentaram sinais neurológicos mais severos conforme o TCN e o TP aumentaram e o LCE sofreu alteração, mesmo colhido cranial ao local da lesão e auxiliou o clínico em reforçar a suspeita clínica, mas não confirmou, as principais doenças neurológicas em cães.
Influência do polipirrol e dos níveis de salinidade na formação de biofilme em Aeromonas spp.
Authors: Pires Isabelle Caroline , Freire Naiana B. , Fernandes Antônio W.C. , Souza Renata F.S. , Silva Jr Fernando A.G. , Oliveira Helinando P. , Costa Mateus M.
Published: November 2018

RESUMO: Bactérias do gênero Aeromonas são patógenos altamente disseminados no ambiente aquático, responsáveis por grandes perdas econômicas na piscicultura de diversos países. São micro-organismos oportunistas e sua patogenicidade está ligada a alguns fatores de virulência, como a formação de biofilme. O estresse salino é um dos fatores que favorecem a formação dessas colônias e, consequentemente, o aumento de infecções. Essas infecções quando estão associadas ao biofilme são ainda mais resistentes aos antimicrobianos. Nesse contexto, o polipirrol destaca-se como uma alternativa antimicrobiana por possuir vários atributos terapêuticos e não apresentar toxicidade aos organismos. Dessa forma, o objetivo desse estudo foi avaliar o perfil de susceptibilidade e a capacidade de formação de biofilme dos isolados de Aeromonas spp. associados aos diferentes níveis de salinidade e polipirrol. Determinou-se a atividade antibacteriana dos isolados e ensaios de motilidade foram realizados com bactérias que carreavam o gene fla. Também verificou-se a capacidade do cloreto de sódio e polipirrol em interferir na formação do biofilme. Os resultados foram evidenciados com a microscopia eletrônica de varredura. As concentrações de 2 e 3% de NaCl inibiram a motilidade bacteriana. Na formação do biofilme, 83% dos isolados bacterianos induziram a produção na concentração de 0,25%. O polipirrol causou a morte de todos os isolados testados na concentração de 125μg/mL. Além disso, esse composto diminuiu a motilidade bacteriana nas concentrações de 0,25 a 3%, sendo que em relação à produção de biofilme, não houve interferência. Esses resultados evidenciam que os diferentes níveis de NaCl influenciam na formação do biofilme favorecendo a persistência da infecção. Este estudo também realçou a potencialidade do polipirrol como agente bactericida, sendo uma alternativa eficaz às drogas antimicrobianas para o tratamento das infecções causadas por Aeromonas spp.
Jogo de Física de partículas: Descobrindo o bóson de Higgs
Authors: Souza M. A. M. , Nascimento A. C. S. , Costa D. F. , Ferreira O.
Published: November 2018

Resumo Neste artigo é proposto a utilização de um jogo didático como complementação metodológica para ensinar Física de altas energias, abordando a temática de Física de Partículas Elementares. A ideia é utilizar estratégias lúdicas e divertidas para ensinar fenômenos estudados no Grande Colisor de Hádrons (LHC), levando os participantes a fazerem novas descobertas didático-científicas, adquirir conhecimento e construírem conceitos que serão utilizados na formulação da teoria do bóson de Higgs e de sua detecção no experimento ATLAS. Embora tais conceitos tenham uma descrição quantitativa extremamente complexa, até certo ponto arraigada a uma análise experimental, é possível torná-la qualitativamente acessível sem precisar recorrer a formulações matemáticas avançadas, conservando, entretanto, seu caráter técnico.
Population fluctuation and food preference of African snail by horticulture crops
Authors: Santos Lindinalva dos , Barbosa-Negrisoli Carla Ruth de Carvalho , Santos Maciel Bispo dos , Negrisoli Junior Aldomário Santo
Published: November 2018

ABSTRACT: The African snail Achatina fulica (Bowdich, 1822), originally from Africa, was introduced in Brazil and since then became an important pest, because of its resistance to abiotic conditions, hermaphroditism, polyphagia and absence of natural enemies. Considered as one of the 100 worst pests in the world, with the record of establishment in almost all Brazilian states, it causes sanitary, ecological and economic losses. In this context, the objective of this study was to determine the population dynamics and food preference of the giant snail in three areas of lettuce, located in Alagoas, Brazil. There was no statistical difference between food preference tests with and without choice among the varieties offered. To the fluctuation of the population of A. fulica, the Pearson correlation coefficients were negative only for temperature, and there was no correlation with precipitation and relative humidity.
Eugenia uniflora L.: potential uses as a bioactive plant
Authors: Moura Gabriela Silva , Oliveira Ivan Júnior de , Bonome Lisandro Tomas da Silva , Franzener Gilmar
Published: November 2018

ABSTRACT: Natural products extracted from plants have always played an important role in the discovery of bioactive substances. This work carried out a review of the literature on the bioactive activities of Eugenia uniflora L. (Surinam cherries), as a potential plant in the various uses, be it medicinal, antimicrobial, antioxidant, insecticide and protective. In the literature, studies were found to confirm the antibacterial activity of E. uniflora leaves extract on Streptococcus, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. The presence of antioxidant compounds as total phenolics, such as anthocyanins and flavonoids, induction in the protection of plants by phytoalexins, as well as insecticidal and anthelmintic effects by the use of the extract of the E. uniflora tree. Although these different potential biotics of E. uniflora have already been reported, further studies are still needed on the use of natural products extracted from E. uniflora for employment for different purposes.
Flowchart of elderly care victms of abuse: an interdisciplinary perspective
Authors: Plassa Bruna Oliveira , Alarcon Miriam Fernanda Sanches , Damaceno Daniela Garcia , Sponchiado Viviane Boacnin Yoneda , Braccialli Luzmarina Aparecida Doretto , Silva Janaina Aparecida Vantin Elias da , Marin Maria José Sanches
Published: November 2018

Abstract Objective: To identify the flows of service for older people, victims of violence in different care services and to analyze the main critical issues. Method: This is a descriptive and exploratory study based on interviews with professionals responsible for: health services; judicial and social care, and with elder abuse victims, in a medium-sized city in the countryside of the state of São Paulo. Data enabled the creation of a flowchart to describe and define the critical issues, according to the model created by Franco and Merhy. Results: The following critical issues were identified: lack of centrality when directing complaints; difficulty to contact 100 hotline; collection of insufficient data on the event; lack of communication among services; victim's withdrawal in the middle of the process; lack of knowledge by the services and the population on social care functions; conflict among services in cases of difficult situations to solve, and lack of intervention by primary health care teams in response to a violence complaint. Conclusions and implications for practice: Critical issues point to the need to enhance interventions from the intersectoral perspective, with the aim to improve older people's quality of health.
Professional nursing identity: a perspective through the brazilian printed media lenses
Authors: Silva Amina Regina , Padilha Maria Itayra , Backes Vânia Marli Schubert , Carvalho Juliana Bonetti de
Published: November 2018

Abstract Objective: To analyze the historical events of the nursing profession presented by the Brazilian print media and that were configured as important in the (re/des) construction of the professional identity, from 1980 to 1986. Method: Qualitative research with a documental historical nature guided by historical investigation process, using 80 articles published in newspapers of great national circulation. Results: They portrayed the nursing struggles and representative entities to improve working conditions, the highlights for intercurrences in the nursing area, as well as the media portrayal of the stereotype of nursing at the time. Conclusion: The stereotypes traced by print media result in a double impact on nursing and its professional identity. On the one hand, it adds visibility to the struggles and gains of the category, and on the other, it generates devaluation by portraits of intercurrences in the exercise of the profession without pertinent contextualization and explanation of the facts that approached and resulted in such an event.