bluuebunny/crossref_metadata_2025 huggingface dataset:
Imperatives of relationship in a workplace
Authors: Tanimu Kenneth
Published: July 2024

There exists limited paper directly highlighting the relationship between value preference and its association with people's expectations from the workplace. Studying personal value preference is important because a substantial body of papers indicate that a specific pattern of value orientations predicts views and hence, it may predict behaviour in the workplace. The value of relationship in a workplace is a strong weapon in any organisation and cannot be underestimated. The relationship of workers in an organisation is core to the survival and growth of such an organisation. Every organisation is concerned with being effective, especially now in a difficult economic environment and in the face of fierce world competition. Secretary should not joke with organization effectiveness because the attainment survival and future of the organization depends on the role the secretary plays in the organization. It is important to allow employees the opportunity to build quality relationships with their co-workers. This will lead to better work, improves Morale, increase engagement and lead to greater satisfaction at work.
Good relationship in workplace as a means of achieving organizational objectives
Authors: Leka Cephas N. , Arikwandu Sympathy , Ozomenam Nwanneka
Published: July 2024

On daily basis the world is becoming a global village through technological advancement. Notwithstanding, the issue of human involvement and participation in workplace can only be minimized but not eliminated. This paper would examine the need for good relationship among workers in workplace in order to achieve the aims and objectives of setting up an organization. It would look at what Human and Public Relationships are; how to relate with superiors, peers, subordinates and clients. Based on findings and conclusions, recommendations were made to solve possible problems or challenges found. Amongst these are, that organizations should always draw the attention of staff on the need to maintain cordial relationships among themselves and with visitors, that employees should avoid being the “black sheep” in the organization.
Competencies required by a professional secretary for effective work in an organization
Authors: John Celestina Dibbari , Udonyah Imoh , Maiyak Mafintin
Published: July 2024

The effectiveness of a professional secretary in an organization cannot be over emphasized. A professional secretary co-ordinates the daily routine and activities of an office, also organizes office schedules and paper work. This paper examines ways in which a professional secretary can bring about the basic skills, thinking skills and personal skills required in a modern office. The paper suggests that a professional secretary should go further for training, this will go a long way to increase competencies. Therefore, a professional secretary should be aligned with modern day realities in their working place which will make them to be competence in their daily works.
Alternative sources of funding ICT resources for OTM programme in polytechnics in Osun state
Authors: Folorunso Isaac Oluwole , Oludele Yemisi L.
Published: July 2024

This study sought for possible alternative sources of funding of ICT resources for OTM programme in polytechnics in Osun State. Research question was raised and self developed questionnaire with 17-item was distributed to 26 respondents in the two selected Polytechnics in Osun State. Frequency and mean methods were used in analyzing the data. Findings from the study reveal that government and managements of institutions alone cannot adequately provide ICT resources needed to effectively deliver the contents of OTM curriculum. For the students to acquire necessary skills, as well as to achieve the aims and objectives of introducing the new curriculum, alumni associations, corporate organizations, wealthy individuals and indeed every stakeholders' assistance are urgently needed to fund OTM programme.
Pengaruh Tugas Kesehatan Keluarga dalam Pencegahan Risiko Jatuh terhadap Kejadian Jatuh pada Lansia
Authors: Yuliyanti Tutik , Dermawan Deden , Rahayuningsih Tutik
Published: July 2024

Dalam melaksanakan program pencegahan risiko jatuh bagi anggota keluarga yang berusia lanjut, tugas kesehatan keluarga meliputi kemampuan mengenal risiko jatuh, mengambil keputusan dalam pencegahan risiko jatuh, merawat anggotanya yang sakit atau yang memerlukan bantuan, memodifikasi lingkungan rumah untuk mencegah risiko jatuh dan memanfaatkan fasilitas kesehatan. Tujuan penelitian ini adalah menganalisis pengaruh tugas kesehatan keluarga dalam pencegahan risiko jatuh terhadap kejadian jatuh pada lansia. Desain penelitian ini adalah deskriptif analitik pendekatan cross sectional dengan analisis data regresi linear sederhana. Teknik pengambilan sampel adalah purposive sampling, yaitu sebanyak 154 keluarga dengan alat ukur dengan kuesioner. Hasil penelitian didapatkan: ada pengaruh signifikan antara tugas kesehatan keluarga dalam pencegahan risiko jatuh terhadap kejadian jatuh pada lansia. Setiap peningkatan 1 skor tugas kesehatan keluarga dalam pencegahan risiko jatuh akan mencegah kejadian jatuh pada lansia sebesar 0.655. Variabel tugas kesehatan keluarga dalam pencegahan risiko jatuh  mampu menjelaskan 10,5% dari faktor risiko jatuh pada lansia, sedangkan sisanya dijelaskan oleh variabel lain. Simpulan: tugas kesehatan keluarga dalam pencegahan risiko jatuh mempengaruhi kejadian jatuh pada lansia. Saran: diharapkan perlu edukasi pelaksanaan tugas kesehatan keluarga terkait program pencegahan risiko jatuh pada lansia.
Kadar Timbal (Pb) dalam Darah Sukarelawan Pengatur Lalu Lintas (Supeltas) di Kota Surakarta Ditinjau dari Usia, Lama Kerja dan Kebiasaan Merokok
Authors: Prabandari Anggraeni Sih , Sari Ajeng Novita , Pramonodjati Fredericus , Wulandari Tata
Published: July 2024

Timbal (Pb) dapat masuk ke dalam darah melalui inhalasi. Sukarelawan pengatur lalu lintas (supeltas) merupakan kelompok berisiko tinggi terhadap paparan Pb karena sering menghirup asap kendaraan bermotor yang mengandung Pb. Selain risiko pekerjaan, tingginya konsentrasi Pb darah dapat dipengaruhi oleh umur, durasi paparan dan kebiasaan merokok. Penelitian ini bertujuan untuk mengetahui kadar timbal dalam darah supeltas berdasarkan usia, masa kerja dan kebiasaan merokok. Jenis penelitian adalah deskriptif analitik dengan desain cross sectional. Jumlah sampel sebanyak 16 orang, berjenis kelamin laki-laki. Spesimen pemeriksaan berupa darah vena yang ditambahkan antikoagulan EDTA. Kadar Pb dalam darah dianalisa Flame Atomic Absorption Spectrophotometer (FAAS). Uji Spearman digunakan untuk mengetahui kekuatan pengaruh usia, lama kerja dan kebiasaan merokok terhadap kadar Pb. Rerata kadar Pb dalam darah supeltas yaitu 117,45 µg/dL. Kadar terendah terdapat pada sampel P10 dan P5 yaitu 3,7 µg/dL sedangkan kadar tertinggi pada P16 sebesar 668,7 µg/dL. Terdapat 75% (12/16) supeltas memiliki kadar Pb di atas normal. Hasil analisis Spearman menunjukkan tidak terdapat hubungan yang signifikan antara kadar timbal dalam darah dengan usia (p-value = 0,507> 0,05), masa kerja (p-value = 0,976>0,05) dan kebiasaan merokok (p-value = 0,543>0,05).
Tingkat Kepuasan Pasien BPJS Rujuk Balik pada Pelayanan Kefarmasian di Apotek Kimia Farma Slamet Riyadi Sukoharjo
Authors: Nisa Qoyyimatun , Hartono H
Published: July 2024

Pharmaceutical care dan kepuasan pasien merupakan orientasi pelayanan kefarmasian yang harus dilakukan oleh apotek. Untuk menjamin mutu pelayanan kefarmasian di Apotek, maka perlu dilakukan evaluasi mutu pelayananan kefarmasian secara terus menerus. Apotek Kimia Farma Slamet Riyadi Sukoharjo merupakan apotek Program Rujuk Balik bekerjasama dengan BPJS Kesehatan dari tahun 2019 sampai sekarang. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pasien BPJS Rujuk Balik pada pelayanan kefarmasian di apotek Kimia Farma Slamet Riyadi Sukoharjo sebagai bahan evaluasi diri guna peningkatan mutu pelayanan kepada pasien. Penelitian ini merupakan penelitian diskriptif yang dilakukan melalui survey observasional tingkat kepuasan model Servqual. Teknik pengambilan sampel dilakukan dengan teknik purposive sampling dengan kriteria inklusi. Analisa hasil dilakukan dengan  perhitungan skor tingkat kepuasan pasien diperoleh dari hasil jawaban pasien menggunakan skala likert. Hasil penelitian tingkat kepuasan pasien BPJS Rujuk Balik yang ada di Apotek Kimia Farma Slamet Riyadi Sukoharjo pada dimensi berwujud dengan skor 90% (sangat puas), dimensi kehandalan 86 % (sangat puas), dimensi daya tanggap 86 % (sangat puas), dimensi jaminan 82 % (sangat puas) dan dimensi empati 87 % (sangat puas). Berdasarkan kelima dimensi kepuasan, dapat disimpulkan bahwa pelayanan kefarmasian BPJS Rujuk Balik di Apotek Kimia Farma Slamet Riyadi Sukoharjo pasien merasa sangat puas dengan persentase sebesar 86%.
An efficient method for extracting pure DNA from the oil seed crop Sesamum indicum L.
Authors: Shah Anshuman , Mishra Pragya , Gadol Nitin , Jain Neha , Kumar Rajeev , Kalia Sanjay , Singh Nagendra Kumar , Rai Vandna
Published: July 2024

Sesame (Sesamum indicum L.) is a vital oil seed crop highly rich in sesamin, sesamolin, and tocopherols, which are some of its nutrient and antioxidant components. Sesame is rich in genetic resources with vast germplasm, tolerance to various biotic and abiotic stresses, and quality-related traits. Therefore, a comprehensive study on searching important genes/quantitative trait loci (QTLs) is needed to get better oil from the plant. Pure DNA is the prerequisite to perform various molecular-level functions, including gene amplification, genomewide association studies, and other molecular breeding applications used in crop improvement. However, it also has high polysaccharides and secondary metabolites that interfere with DNA extraction, and precise quantification of DNA is essential for DNA-related biological functions. Several DNA extraction methods, such as cetyl-tetra methyl ammonium bromide (CTAB), sodium dodecyl sulphate (SDS), and commercially available kits, are present and used in molecular biology applications. Due to the complexity and interference of polysaccharides and polyphenols, the available methods required numerous modifications in the protocol to get pure and intact DNA. This study illustrates several modifications to get the pure DNA using the CTAB-based method with the additional step of adding a high salt concentration, which results in a better quantity and quality of DNA extracted from sesame leaves and root tissue. The lysis buffer and cold storage to efficiently eliminate the polysaccharide components were found to be limiting factors affecting DNA yield; therefore, buffer composition, along with storage duration, was modified in the present study. This method worked well to get good quality and quantity of DNA and will help researchers conduct next-generation sequencing and other genetic investigations directly associated with high-quality DNA in the oilseed crop.
GC-MS and in silico analyses revealed the potential inhibitory activity of compounds isolated from Ciplukan herb (Physalis angulata L.) targeting GLUT-4 receptors
Authors: Rakhmawati Rita , Wahyudi Setyanto Tri , Wahyuningsih Mae Sri Hartati , Mustofa Mustofa , Sadewa Ahmad Hamim
Published: July 2024

The escalating prevalence of diabetes mellitus (DM), a major global health threat and one of the top 10 causes of mortality, is a worrying trend. Prolonged hyperglycemia in people with diabetes triggers oxidative stress, leading to accelerated tissue damage, increased levels of free radicals, and the onset of complications. Our initial exploration of Physalis angulata L, using bioassay-guided isolation and C2C12 insulin resistance monitoring, revealed the compound’s ability to increase cellular glucose uptake. Consequently, there is an urgent need for further drug discovery efforts aimed at deciphering the mechanism of action of compounds targeting GLUT4 receptors in silico. The focus of this study was to predict the mechanism of action of compounds against the AS160 protein to facilitate GLUT4 translocation to the cell surface. Using GC-MS analysis and molecular docking via Autodock Vina, a mixture of blind and targeted docking approaches, isolated compounds were identified. Notably, this study marks the first identification, to the best of our knowledge, of campesterol and stigmasterol in P. angulata L herbs by GC-MS analysis. Through in silico simulations, campesterol and stigmasterol show promising potential in the treatment of type 2 diabetes by targeting the glucose transporter GLUT4 via facilitating GLUT4 translocation. Given their favorable pharmacokinetic properties, these phytoconstituents are potential hypoglycemic agents.
Running into differences
Authors: Psarou Eleni , Patel Shivangi , Schölvinck Marieke
Published: July 2024

Body movement does not significantly increase neuronal activity in the primary visual cortex of marmosets, in contrast to the effects observed in mice.
Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K
Authors: Zheng Lirong , Zhou Bingxin , Wu Banghao , Tan Yang , Huang Juan , Tyagi Madhusudan , Sakai Victoria García , Yamada Takeshi , O’Neill Hugh , Zhang Qiu , Hong Liang
Published: July 2024

The protein dynamical transition at ∼ 200 K, where the biomolecule transforms from a harmonic, non-functional form to an anharmonic, functional state, has been thought to be slaved to the thermal activation of dynamics in its surface hydration water. Here, by selectively probing the dynamics of protein and hydration water using elastic neutron scattering and isotopic labelling, we found that the onset of anharmonicity in the two components around 200 K are decoupled. The one in protein is an intrinsic transition, whose characteristic temperature is independent of the instrumental resolution time, but varies with the biomolecular structure and the amount of hydration, while the one of water is merely a resolution effect.
Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells
Authors: Zhu Yuqing , Cho Kevin , Lacin Haluk , Zhu Yi , DiPaola Jose T , Wilson Beth A , Patti Gary J , Skeath James B
Published: July 2024

Dihydroceramide desaturases convert dihydroceramides to ceramides, the precursors of all complex sphingolipids. Reduction of DEGS1 dihydroceramide desaturase function causes pediatric neurodegenerative disorder hypomyelinating leukodystrophy-18 (HLD-18). We discovered that
infertile crescent (ifc)
, the
Drosophila DEGS1
homolog, is expressed primarily in glial cells to promote CNS development by guarding against neurodegeneration. Loss of
ifc
causes massive dihydroceramide accumulation and severe morphological defects in cortex glia, including endoplasmic reticulum (ER) expansion, failure of neuronal ensheathment, and lipid droplet depletion. RNAi knockdown of the upstream ceramide synthase
schlank
in glia of
ifc
mutants rescues ER expansion, suggesting dihydroceramide accumulation in the ER drives this phenotype. RNAi knockdown of
ifc
in glia but not neurons drives neuronal cell death, suggesting that
ifc
function in glia promotes neuronal survival. Our work identifies glia as the primary site of disease progression in HLD-18 and may inform on juvenile forms of ALS, which also feature elevated dihydroceramide levels.
Mucormicosis: un dulce enemigo, serie de casos
Authors: Manrique-Castaño Santiago , Velásquez-Trujillo Luis Armando , Ángel Correa Mariana , Bravo José Humberto , Matta Cortes Lorena
Published: July 2024

La mucormicosis es una infección fúngica poco frecuente causada por hongos del orden Mucorales, la cual se presenta en individuos inmunocomprometidos o con pérdida de la integridad de la barrera de piel o mucosas.Se reportan cuatro casos de mucormicosis rinocerebral atendidos en un hospital de tercer nivel de Cali (Colombia) durante un periodo de tres años. Los cuatro pacientes presentaron diferentes cuadros clínicos y tiempos de evolución. Todos tenían diagnóstico de diabetes mellitus de tipo 2, de novo o previo, con una hemoglobina glucosilada de ingreso mayor del 10 % y en todos se descartaron otras enfermedades que explicaran su compromiso inmunitario. La mucormicosis se diagnosticó por la visualización directa de hifas hialinas sincitiales (coenocytic) en las biopsias tomadas.El pilar del tratamiento fue la anfotericina B liposómica junto con el desbridamiento quirúrgico. Dos pacientes presentaron coinfección bacteriana. De los cuatro, uno firmó su egreso voluntario sin completar el tratamiento y otro falleció. Los dos pacientes restantes han asistido a los controles y han mostrado una adecuada evolución.
Aproximación ecológica a las características y factores determinantes de la violencia sexual contra adolescentes en Perú
Authors: Enríquez Yordanis , Cahui Claudia Rebeca , Díaz Giovani Martín
Published: July 2024

Introducción. La violencia sexual contra los adolescentes es un problema global que afecta a jóvenes de todo el mundo. El modelo ecológico examina sus formas y factores determinantes a través de niveles interconectados.Objetivo. Determinar la frecuencia, las características y los predictores de la violencia sexual contra adolescentes escolarizados en Perú.Materiales y métodos. Se llevó a cabo un estudio transversal en el cual se analizaron de manera secundaria los datos de la Encuesta Nacional de Relaciones Sociales (2019). Una muestra probabilística estratificada incluyó a 1.579 jóvenes de 12 a 17 años de 93 escuelas. Con el cuestionario se evaluó la violencia sexual en la familia y en la escuela. Se estimaron modelos mediante análisis de regresión logística, calculando la razón de momios (odds ratio, OR).Resultados. El 18,68 % (IC95%: 16,80-20,60) sufrió algún tipo de agresión sexual. Además, el 9,75 % (IC95%: 8,28-11,21) informó haber sido tocado en alguna parte del cuerpo y el 1,84 % (IC95%: 1,17-2,50) informó que fue víctima de violación. La edad se identificó como factor de riesgo en el microsistema (OR=1,48) (IC95%: 1,26-1,74), mientras que la edad de la primera violencia sexual actuó como factor protector (OR=0,61) (IC95%: 0,54-0,69). Además, en el macrosistema, la percepción de que la violencia ocurre principalmente fuera del hogar incrementó el riesgo (OR=2,06) (IC95%: 1,01-4,19).Conclusión. Aproximadamente, dos de cada diez encuestados informaron haber experimentado algún tipo de violencia sexual, siendo el acoso verbal y el contacto personal invasivo los más comunes. Ningún nivel del modelo ecológico o factor único puede explicar completamente la violencia sexual contra los adolescentes sin considerar su interconexión ecológica.
Prevalencia de la resistencia a macrólidos y aminoglucósidos en los complejos Mycobacterium avium y M. abscessus y en Mycobacterium chelonae identificados en el Laboratorio Nacional de Referencia de Colombia entre el 2018 y el 2022
Authors: Llerena Claudia , Valbuena Yanely Angélica , Zabaleta Angie Paola , García Angélica Nathalia
Published: July 2024

Introducción. Mycobacterium chelonae y los complejos Mycobacterium avium y M. abscessus, son agentes patógenos emergentes causantes de micobacteriosis. El tratamiento de esta infección depende de la especie y la subespecie identificadas. Los fármacos de elección son los macrólidos y aminoglucósidos, contra los cuales se ha reportado resistencia; por esta razón, el determinar el perfil de sensibilidad le permite al médico tratante comprender mejor el pronóstico y la evolución de estas infecciones.Objetivo. Describir los perfiles de sensibilidad ante macrólidos y aminoglucósidos, de los cultivos identificados como complejo Mycobacterium avium, complejo M. abscessus o especie M. chelonae, en el Laboratorio Nacional de Referencia de Micobacterias durante los años 2018 a 2022.Materiales y métodos. Se llevó a cabo un estudio descriptivo del perfil de sensibilidad a macrólidos y aminoglucósidos, de los cultivos identificados como complejo M. avium, complejo M. abscessus o M. chelonae, mediante la metodología GenoType® NTM-DR.Resultados. Los cultivos del complejo M. avium fueron 159 (47,3 %), de los cuales, 154 (96,9 %) fueron sensibles y 5 (3,1 %) resistentes a los macrólidos; todos fueron sensibles a los aminoglucósidos. Del complejo M. abscessus se estudiaron 125 (37,2 %) cultivos, 68 (54,4 %) resultaron sensibles y 57 (45,6 %) resistentes a los macrólidos; solo un cultivo (0,8 %) fue resistente a los aminoglucósidos. De M. chelonae se analizaron 52 cultivos (15,5 %), todos sensibles a los macrólidos y aminoglucósidos.Conclusiones. En las tres especies de micobacterias estudiadas, la resistencia contra la amikacina fue la menos frecuente. La identificación de las subespecies y los perfiles de sensibilidad permiten instaurar esquemas de tratamiento adecuados, especialmente en las micobacteriosis causadas por M. abscessus.
Short-term microplastic effects on marine meiofauna abundance, diversity and community composition
Authors: de França Flávia J.L. , Moens Tom , da Silva Renan B. , Pessoa Giovanna L. , França Débora A.A. , Dos Santos Giovanni A.P.
Published: July 2024

Background

Due to the copious disposal of plastics, marine ecosystems receive a large part of this waste. Microplastics (MPs) are solid particles smaller than 5 millimeters in size. Among the plastic polymers, polystyrene (PS) is one of the most commonly used and discarded. Due to its density being greater than that of water, it accumulates in marine sediments, potentially affecting benthic communities. This study investigated the ingestion of MP and their effect on the meiofauna community of a sandy beach. Meiofauna are an important trophic link between the basal and higher trophic levels of sedimentary food webs and may therefore be substantially involved in trophic transfer of MP and their associated compounds.

Methods

We incubated microcosms without addition of MP (controls) and treatments contaminated with PS MP (1-µm) in marine sediments at three nominal concentrations (103, 105, 107particles/mL), for nine days, and sampled for meiofauna with collections every three days. At each sampling time, meiofauna were collected, quantified and identified to higher-taxon level, and ingestion of MP was quantified under an epifluorescence microscope.

Results

Except for Tardigrada, all meiofauna taxa (Nematoda, turbellarians, Copepoda, Nauplii, Acari and Gastrotricha) ingested MP. Absorption was strongly dose dependent, being highest at 107 particles/mL, very low at 105 particles/mL and non-demonstrable at 103 particles/mL. Nematodes accumulated MP mainly in the intestine; MP abundance in the intestine increased with increasing incubation time. The total meiofauna density and species richness were significantly lower at the lowest MP concentration, while at the highest concentration these parameters were very similar to the control. In contrast, Shannon-Wiener diversity and evenness were greater in treatments with low MP concentration. However, these results should be interpreted with caution because of the low meiofauna abundances at the lower two MP concentrations.

Conclusion

At the highest MP concentration, abundance, taxonomic diversity and community structure of a beach meiofauna community were not significantly affected, suggesting that MP effects on meiofauna are at most subtle. However, lower MP concentrations did cause substantial declines in abundance and diversity, in line with previous studies at the population and community level. While we can only speculate on the underlying mechanism(s) of this counterintuitive response, results suggest that further research is needed to better understand MP effects on marine benthic communities.
Genome-wide analysis of cellulose synthase (CesA) and cellulose synthase-like (Csl) proteins in Cannabis sativa L
Authors: Sipahi Hulya , Haiden Samuel , Berkowitz Gerald
Published: July 2024

The cellulose and hemicellulose components of plant cell walls are synthesized by the cellulose synthase (CESA) and cellulose synthase-like (CSL) gene families and regulated in response to growth, development, and environmental stimuli. In this study, a total of 29 CESA/CSL family members were identified in Cannabis sativa and were grouped into seven subfamilies (CESA, CSLA, CSLB, CSLC, CSLD, CSLE and CSLG) according to phylogenetic relationships. The CESA/CESA proteins of C. sativa were closely related phylogenetically to the members of the subfamily of other species. The CESA/CSL subfamily members of C. sativa have unique gene structures. In addition, the expressions of four CESA and 10 CsCSL genes in flower, leaf, root, and stem organs of cannabis were detected using RT-qPCR. The results showed that CESA and CSL genes are expressed at varying levels in several organs. This detailed knowledge of the structural, evolutionary, and functional properties of cannabis CESA/CSL genes will provide a basis for designing advanced experiments for genetic manipulation of cell wall biogenesis to improve bast fibers and biofuel production.
Immune infiltration and prognosis in gastric cancer: role of NAD+ metabolism-related markers
Authors: Xing Yu , Zhang Zili , Gao Wenqing , Song Weiliang , Li Tong
Published: July 2024

Background

This study endeavored to develop a nicotinamide adenine dinucleotide (NAD+) metabolism-related biomarkers in gastric cancer (GC), which could provide a theoretical foundation for prognosis and therapy of GC patients.

Methods

In this study, differentially expressed genes (DEGs1) between GC and paraneoplastic tissues were overlapped with NAD+ metabolism-related genes (NMRGs) to identify differentially expressed NMRGs (DE-NMRGs). Then, GC patients were divided into high and low score groups by gene set variation analysis (GSVA) algorithm for differential expression analysis to obtain DEGs2, which was overlapped with DEGs1 for identification of intersection genes. These genes were further analyzed using univariate Cox and least absolute shrinkage and selection operator (LASSO) regression analyses to obtain prognostic genes for constructing a risk model. Enrichment and immune infiltration analyses further investigated investigate the different risk groups, and qRT-PCR validated the prognostic genes.

Results

Initially, we identified DE-NMRGs involved in NAD biosynthesis, with seven (DNAJB13, CST2, THPO, CIDEA, ONECUT1, UPK1B and SNCG) showing prognostic significance in GC. Subsequent, a prognostic model was constructed in which the risk score, derived from the expression profiles of these genes, along with gender, emerged as robust independent predictors of patient outcomes in GC. Enrichment analysis linked high-risk patients to synaptic membrane pathways and low-risk to the CMG complex pathway. Tumor immune infiltration analysis revealed correlations between risk scores and immune cell abundance, suggesting a relationship between NAD+ metabolism and immune response in GC. The prognostic significance of our identified genes was validated by qRT-PCR, which confirmed their upregulated expression in GC tissue samples.

Conclusion

In this study, seven NAD+ metabolism-related markers were established, which is of great significance for the development of prognostic molecular biomarkers and clinical prognosis prediction for gastric cancer patients.
Lyrical Perspectives on Lady Bryon’s I Talk Black and Simone Lagrand’s Nous sommes des rivières
Authors: Couvin Sarah
Published: July 2024

The comparative study that I propose through the present article is not only a structured overview – of I Talk Black, written and spoken by the artist Lady Brion, from Maryland, in 2018, and Nous sommes des rivières, written and spoken by the artist Simone Lagrand, from Martinique, in 2014 – but a clear statement on the lyrical situation in the Americas. This paper comprehends various insights on an African-American woman’s musicality and a Franco-Creole-Caribbean woman’s orality. Taken together, these Black women’s pieces of work call for demonstrative freedom and compelling peace. If Brion says that, “This slang is semantic resistance” (I Talk) and Lagrand affirms that, “Il est dit que toutes les rivières descendent à la mer” (Nous sommes) therefore, where do their narratives meet each other? What’s the link between Brion’s “cornbread accent” and Lagrand’s “voyage vers nous-même”? To what extent do the selected authors’ prevailing rhetorical strategies echo one another? I will address how English, French and Creole languages evoke the creative process that nourishes the artists that I have met in person and interviewed in the context of my Ph.D. research on oral literatures such as Slam Poetry and Spoken Word in the Americas.
Tecendo diálogos: uma análise da ética do discurso de Jürgen Habermas nos processos estruturais
Authors: Freitas Leonardo Buissa , Mota Márcia Oliveira Alves da
Published: July 2024

Este artigo examina os princípios da ética do discurso de Jürgen Habermas e a abertura procedimental nos processos estruturais, destacando a ênfase na ampliação da participação e do diálogo. A análise concentra-se na Câmara Judicial da Lagoa da Conceição, sua criação e pressupostos no processo judicial no interior da Justiça Federal em Santa Catarina. A teoria habermasiana é identificada nos processos estruturais, promovendo espaços de diálogo e entendimento, exemplificados pela mencionada Câmara Judicial, que possibilita maior adesão dos sujeitos processuais. O resultado que se chega é que a criação de tais espaços dá voz a diversos participantes, permitindo a autocompreensão do comando, construído pelos próprios envolvidos. Além disso, busca-se extrair substratos em Habermas para contribuir na discussão sobre o aprofundamento da abertura dialogal nesses contextos.
Carotid Dolichoarteriopathies: A Comprehensive Overview
Authors: Iomini Pablo , Beigelman Ricardo , Ambrosio Giuseppe , Izaguirre Andrés , Milei José
Published: July 2024

Carotid dolichoarteriopathies (CDA) represent a group of morphological abnormalities, with changes in the geometry and tortuosity of the carotid arteries. They were described in 1925 for the first time and were classified in three types according to the angle of torsion, in tortuosity (angle > 90°), coiling (S-shaped curve or loop) and kinking (angle < 90°). The pathophysiology of CDA is controversial and includes congenital mechanisms, genetic factors, connective tissue diseases, acquired mechanisms which can be associated with but not dependent on cardiovascular risk factors, and anomalies of the cervical spine. CDA have been associated with different cardiovascular and cerebrovascular events secondary to hemodynamic abnormalities, thromboembolism and cerebrovascular insufficiency and ischemia. However, the evidence is limited and for some authors they are more of a curiosity than a real predictor of ischemic events. Other studies support the clinical value of the diagnosis and follow-up of CDA and their understanding not only by internists, cardiologists and neurologists, but also by surgeons and otolaryngologists. Several authors proposed different therapeutic strategies to correct CDA, including surgical procedures. However, the indications and management approaches are controversial, and further randomized, multicenter, prospective studies are required to determine the most appropriate course of action. Until then, imaging techniques remain the basis for the etiologic diagnosis of cerebrovascular adverse events when all other causes have been excluded, and close clinical monitoring and follow-up of patients remain key strategies for the prevention of secondary events.
Rapid-Deployment Valves versus Conventional Valves in Aortic Valve Replacement in Intermediate-Risk Patients
Authors: Fortunato Germán A. , D´AngeloG Tomás , Busnelli Guido , Tamara Carlos A. , Sultano Nicolás , Theaux Jacinto , Espector Patricio , Valdecantos Florencia , Posatini Ricardo , Bianco Juan , Rossi Emiliano , Kotowicz Vadim
Published: July 2024

Background: Aortic valve replacement (AVR) in intermediate-risk (IR) patients is particularly challenging when determining the type of prosthesis to use. Rapid-deployment valves (RD-V) are emerging as a potential alternative in this patient population. Objectives: To compare early mortality, postoperative complications, and transvalvular hemodynamic parameters between AVR with conventional valves and RD-V in IR patients. Methods: We conducted a retrospective observational study of consecutive IR patients (STS-Prom score 4-8) undergoing AVR with conventional prostheses and RD-V between 2007 and 2023. Results: A total of 205 patients were included (140 AVR vs. 65 RD-V). Surgical risk was similar between both groups (STS-Prom 5.07 % vs. 5.7 % respectively, p = 0.211). The minimally invasive approach was more common in the RD-V group (32.3% vs. 0.7%, p < 0.001). The cardiopulmonary bypass time and aortic cross-clamp time was significantly shorter in the RD-V group (134.5 vs. 100 min and 104 vs. 73 min, respectively, p < 0.001). There was a trend to lower incidence of pacemaker implantation in the conventional valve group (4.3% vs. 10.8%, p = 0.075). There were no significant differences in postoperative complications, and a strong trend to lower 30-dat mortality with RD-V (0% vs. 5.7% for conventional valves, p = 0.057). The mean postoperative gradient across the prosthesis was significantly lower in the RD-V group (7.90 ± 3.3 mm Hg vs. 12.74 ± 6.07 mm Hg, p < 0.001). There were no differences in the incidence of valve thrombosis or prosthetic endocarditis. Conclusions: Rapid deployment valves demonstrated trend to lower mortality, shorter cardiopulmonary bypass time and aortic cross-clamp time, improved hemodynamic profile, and were easier to implant via a minimally invasive approach.
The Expenditure Rule in the Spanish Organic Law on Budgetary Stability and Financial Sustainability and its Impact on the Autonomous Communities
Authors: Melián-González Arturo ,   Universidad de Las Palmas de Gran Canaria
Published: July 2024

Spanish Autonomous Communities cannot incur a structural deficit, and their debt levels must not exceed the limit set out in the organic law on budgetary stability. This law also includes an expenditure rule that limits their non-financial expenditure. In the last few years, significant differences have been found between the constraints imposed on these regional governments through the budget balance rule and the expenditure rule, which could hinder the internal consistency of the fiscal framework. The present work identifies the reasons for such differences, and examines them for the regional subsector as a whole and for each autonomous community
Exploring the Influence of Financial Literacy on Mobile Financial Service Usage: An Ordered Probit Analysis
Authors: Dong SiQi
Published: July 2024

Mobile financial service, an emerging form of financial services that has developed alongside the internet and mobile devices, are becoming increasingly significant in the global financial market. Financial literacy is crucial for safely and effectively using these services, as it equips individuals with the necessary knowledge and skills to navigate the digital financial landscape, make informed decisions, and manage their finances responsibly. This study explores the link between financial literacy and the use of mobile financial services, aiming to promote financial inclusion and help users benefit from mobile banking technologies.  The results indicate that the impact of objective financial literacy varies significantly across different types of mobile financial services. It boosts the utilization of mobile banking services, with coefficient 0.025 (p<0.01), while simultaneously reducing the frequency of mobile payments and transfers, with coefficients -0.041 and -0.012 respectively (p<0.01). The results also show that subjective financial literacy always positively relate to the use of mobile banking, mobile payments and mobile transfers, with coefficients 0.038, 0.044 and 0.03 respectively (p<0.01). Further, this paper investigates how financial literacy miscalibration affects the use of mobile financial services. The results show that individuals who over-evaluated their financial literacy are more likely to use mobile financial services than individuals who under-evaluated or correct-evaluated their financial literacy. The results serve as decisive evidence for policymakers to enhance consumer financial literacy, thereby improving their use of mobile financial services. Future studies could delve deeper into the underlying reasons for the differential impact of objective financial literacy on various MFS types.
Development of Climate Resilient Genotypes in Desi Chickpea (Cicer arietinum L.)
Authors: Chaudhari Snehal. R. , Kute N. S. , Shinde G. C. , Ubale Sonali. P. , Parmar J. N.
Published: July 2024

For development of climate resilient genotypes of chickpea for yield and yield contributing characters the present study was undertaken at Pulses Improvement Project, MPKV, Rahuri during Rabi season of 2021-22. The twelve genotypes and four check varieties were evaluated under three different environmental conditions. The data was subjected to ANOVA and Eberthart and Russel model. The analysis of pooled variance showed a significant connection among genotypes, environment (Linear) and genotypes x environment (Linear) almost for all characters except for number of seeds per pod.  The genotypes Phule G 181603, Phule G 181609, Phule G 181667, Vijay and Phule Vikrant exhibited average stability for grain yield per plant over all three environments. The varieties Digvijay and Phule Vikram was found below average stable so they could be suitable for poor environment and genotypes Phule G 181102 and Phule G 1210-16-1 showed stability under favorable environments.
Character Association and Path Coefficient Analysis of Morphological Quantitative Traits in Ethiopian Kale (Brassica Carinata A.)
Authors: Asfaw Yenenesh , Birhan Techale , Tabor Getachew
Published: July 2024

The present study was conducted at Debre zeit Agricultural Research Center to determine the extent of association among yield and its related traits of 49 accessions and to assess the direct and indirect effects of yield component traits on leaf yield of Ethiopian Kale. The accession were studied for fourteen quantitative traits using 7 × 7 simple lattice design in 2018 cropping season. The accessions were collected from diverse agro ecological area.  The research findings indicated that leaf yield per plant exhibited positive and significant phenotypic and genotypic association with all factors except for leaf width and leaf petiole thickness. The result revealed that days to first leaf picking, leaf fresh weight per plant, leaf dry matter content and number of leaves per plant were the most important yield components as they exerted positive direct effect on leaf yield as well as positive genotypic and phenotypic association with each other explaining the existence of significant association. This highlighting their importance in improving Ethiopian kale yield.
Effect of Nixtamalization on the Physical Functional and Nutritional Properties of Foxtail Millet Flour
Authors: Mounika V. Naga , Kumari B. Anila , W. Jessie Suneetha , Rani Neela
Published: July 2024

Aims: To investigate the physico-functional and nutritional properties of nixtamalized foxtail millet and compare them with non-nixtamalized millet. Nixtamalization is an ancient processing technique involving the soaking and cooking of grains in an alkaline solution, typically lime water. This process enhances the nutritional profile, flavor, and functional properties of grains, making them more suitable for various culinary applications. Minor millets possess immense nutritional value, comparable to that of wheat, rice, and maize.
Study Design: Experimental design.
Place and Duration of Study: Foxtail millet grain and maize grain were procured from Millet Processing and Incubation Centre (MPIC) PJTSAU, Rajendranagar, Hyderabad and food grade calcium hydroxide chemical was purchased from local market in Hyderabad. This study was concluded during 2023.
Methodology: Maize grain and foxtail millet were nixtamalized and analyzed for physical parameters viz. thousand kernel weight, thousand kernel volume and bulk density. Functional properties of nixtamalized grains such as swelling power, swelling capacity water solubility index, water holding capacity, oil absorption capacity; water absorption capacity and oil retention capacity and nutritional properties like moisture, fat, ash, crude fibre, carbohydrates, protein, energy.
Results: It was found that physical parameters viz. thousand kernel weight, thousand kernel volume and bulk density decreased in nixtamalized maize and foxtail grains. Functional properties of nixtamalized maize and foxtail flours such as swelling power, water solubility index, water holding capacity oil absorption capacity; water absorption capacity and oil retention capacity also increased significantly (p≤0.05) and swelling capacity significantly decreased in nixtamalized maize and foxtail flours. Significant increase (p≤0.05) in moisture NM (34.31%) NF3 (27.51%), ash content NM (49.61%) NF3 (2.37%), carbohydrate content (2.35%) NF3 (2.10%) and fat content NM (35.85%) NF3 (26.30%), crude fibre NM (26. 35%) NF3 (29.22%), energy NM, (3.2%), NF3 (3.56%) in nixtamalized grains was observed while protein value of nixtamalized grains were significantly lower NM (11.76%) NF3 (6.50%) compared to untreated grains.
Genetic Variability Studies for Yield and its Attributing Traits in Rice F4 Mapping Population (Oryza sativa L.)
Authors: G. Niharika , M. B. Kalyani , V. Hemalatha , Rao D. Sanjeeva
Published: July 2024

An experiment was conducted at ICAR-IIRR during the wet season of 2023 in a mapping population derived from the cross TI-128 X BPT-5204, along with five checks in an augmented block design with eight blocks. This study revealed that, significant variability was present among the population for all the traits examined. High genotypic coefficient of variation was observed for number of tillers per plant (29.68), number of productive tillers per plant (30.56) and total number of grains per panicle (29.66). High phenotypic coefficient of variation and genotypic coefficient of variation was observed for the trait grain yield per plant. High heritability coupled with high genetic advance as percent of mean was recorded for number of tillers per plant, number of productive tillers per plant, total number of grains per panicle and grain yield per plant showing that these traits are regulated by additive gene effects, making them suitable for selection criteria in rice breeding programs. The traits viz., number of tillers per plant (0.42***), number of productive tillers per plant (0.41***), filled grains per panicle (0.20**), total number of grains per panicle (0.18**) and test weight (0.18**) exhibited significantly positive association with grain yield per plant.
Market Potential and Farmers' Buying Behaviour towards Cumin Seeds in Rajkot District, Gujarat, India
Authors: Olakiya Romit , Lad Yogeshkumar A.
Published: July 2024

The Indian agriculture sector heavily relies on quality seeds for optimal crop productivity. The Indian seed industry plays a crucial role in providing high-quality seeds to farmers. Hybrid seeds are preferred over open-pollinated varieties, and quality seeds not only increase yield but also reduce production costs. The majority of farmers in Rajkot District are middle-aged, with varied education levels and predominantly low incomes. Experienced middle-aged farmers dominate the region, with small and semi-medium landholdings. Different crops are grown across the Kharif, Rabi, and summer seasons, highlighting diverse cropping patterns. The survey in Rajkot District reveals diverse irrigation sources, with various preferences for cumin seed brands among farmers. Factors influencing cumin seed purchases include performance, branding, quality, growth, and price. Retailers' suggestions, demonstrations, and farmers' meetings are the most effective marketing tools. Overall, 61.84% of respondents rated their experience as good, suggesting satisfaction with products and services, but there is room for improvement.
Effect of Plant Growth Regulators on Growth, Yield and Quality of Chilli (Capsicum annuum L.) in cv. Bidhan Chilli-4
Authors: Nirankar  , Mandal Joydip , Parveen Alina , Singh Anil Kumar , Singh Shivam Kumar , Kishor Braj
Published: July 2024

Present experiment entitled “Effect of Plant Growth Regulators on Growth, Yield and Quality of Chilli (Capsicum annuum L.) in cv. Bidhan Chilli-4" was conducted at experimental farm of Horticulture and Post-harvest Technology, Palli Siksha Bhavana, Palli Shikhsha Bhavana Visva Bharati West Bengal during rabi season of 2020. The experiment was laid out in randomized block design (RBD) with three replications and ten treatments. The concentrations of treatments were T1 =NAA 25 ppm, T2 = NAA 50 ppm, T3 = NAA 75 ppm, T4 = GA3 5 ppm, T5 = GA3 15 ppm, T6 = GA3 30 ppm, T7 = CCC 200 ppm), T8= CCC 400 ppm, T9 = CCC 600 ppm and T10 Control. The result of the study revealed that maximum plant height (30.96, 44.40, 54.06 and 67.01cm at 30,60, 90 and 120 DAT respectively), number of branches per plant (8.96, 13.43, 18.00 and 23.53 at 30, 60, 90 and 120 DAT respectively), plant spread (19.50, 30.96, 40. 10 and 54.73 cm at 30, 60, 90 and 120 DAT respectively), flowers per plant ( 400.20), fruits per plant (144.33),  fruit length ( 9.63 cm), breadth of  fruit (1.93 cm ), yield per plant ( 399.43 g), yield per plot ( 98.74 kg/ plot) , yield per hectare (134.53 q/ha), ascorbic Acid (190.76mg/100g), capsaicin ( 0.38 %) capsanthin content (296.109 ASTA Unit), Oleoresin  content  (11.57%)  and minimum days required to 50% flowering (41.68 DAT), were recorded in treatment T3- NAA (75 ppm). Therefore, it is recommended to employ the NAA 75 ppm to chilli growing farmers to enhance growth and maximize yield.
Semidiurnal tidal currents in the deep ocean near the East Pacific Rise between 9° and 10°N
Authors: Liang Xinfeng
Published: June 2014

Spatial and temporal variations of the semidiurnal tidal currents, especially the baroclinic components, in the deep ocean near a segment of the East Pacific Rise (EPR) are examined using observations from a set of current meter moorings. Over the ridge crest, the baroclinic semidiurnal tidal current is dominated by the zonal component and is coherent along the observed ridge segment. In the direction across the ridge crest, the baroclinic semidiurnal tidal current is not coherent and its magnitude decreases away from the ridge crest. Vertically, the baroclinic semidiurnal tidal current covaries in a few hundred meters near the seafloor. Both the semidiurnal kinetic energy (KE) and shear show significant subinertial temporal variations. By comparing with background forcings, the author found that the subinertial variation of the semidiurnal tides over the ridge crest is related to both the spring‐neap cycles and the eddy‐induced low‐frequency flows in the deep ocean, particularly their cross‐ridge components. The observation that the baroclinic tidal currents at the axial stations flowing perpendicularly to the ridge crest suggests that the baroclinic semidiurnal tides at the axial stations are generated locally. It is therefore probable that the subinertial variation of the baroclinic semidiurnal tides near the EPR is due to the eddy‐modulated internal tide generation. Since the mesoscale eddies in the eastern tropical Pacific vary with the state of the climate, the observed eddy‐modulated internal tide generation connects climate change and variability to the physical and biogeochemical dynamics in the deep ocean and implies an unexplored feedback mechanism potentially affecting the climate system.