bluuebunny/crossref_metadata_2025 huggingface dataset:
The ovarian reserve as target of insulin/IGF and ROS in metabolic disorder-dependent ovarian dysfunctions
Authors: Dri Maria , Klinger Francesca Gioia , De Felici Massimo
Published: August 2021

It is known for a long time that metabolic disorders can cause ovarian dysfunctions and affect a woman’s fertility either by direct targeting follicular cells and/or the oocytes or by indirect interference with the pituitary-hypothalamic axis, resulting in dysfunctional oogenesis. Such disorders may also influence the efficiency of the embryo implantation and the quality of the embryo with permanent effects on the fertility and health of the offspring. Thanks to the expanding knowledge on the molecular mechanisms governing oogenesis and folliculogenesis in mammals, we are beginning to understand how such disorders can negatively affect this process and consequently fertility in women. In the present review, we point out and discuss how the disturbance of insulin/IGF-dependent signalling and increased reactive oxygen species (ROS) level in the ovary typically associated to metabolic disorders such as type II diabetes and obesity can dysregulate the dynamics of the ovarian reserve and/or impair the survival and competence of the oocytes.

Lay summary

In women, a progressive decline and depletion of the primary ovary reserve, which represents the reserve of immature eggs, are a challenging condition in the field of reproductive medicine. This decline, occurring physiological with age, is the main determinant of the age at the onset of menopause. Concomitant with the reduction in their number, the quality of the eggs also decreases with age. Metabolic disorders such as diabetes and obesity can cause ovarian dysfunctions and affect a woman’s fertility mainly by direct targeting the egg stockpile or by indirect interference with the production of reproductive hormones. Here, we report up-to-date data and discuss results about how disturbance of insulin-dependent signalling and increased oxidative stress in the ovary, usually associated to metabolic disorders, can dysregulate the dynamics of the primary ovary reserve and/or impair the survival and quality of the eggs.
TEORIA DO NÚCLEO DO EU DE ROJAS-BERMÚDEZ E SUA CORRELAÇÃO COM O IMAGODRAMA
Authors: Guimarães Leonídia Alfredo
Published: August 2021

O objetivo deste artigo é apresentar uma leitura teórica da Núcleo do Eu, mais próxima à teoria da Matriz de Identidade de J. L. Moreno, desenvolvendo com maior profundidade o conceito de Eu incipiente de Rojas-Bermúdez. Associo essa vivência egoica às relações estabelecidas entre o bebê e seu núcleo familiar, logo após o reconhecimento de um Eu minimamente estável, em condições neuropsicológicas para vincular-se às imagos materna, paterna e fraterna. De acordo com essa leitura, o Núcleo do Eu completa sua estruturação aos 4 anos de idade, em conformidade com a Escola Rojas Bermúdez, após realizar-se o processo de síntese dessa matriz nuclear, de onde emerge o Eu Natural e posteriormente, o Eu Social, como produto da triangulação e circularização de papéis. A técnica de construção de imagens é o método que fundamenta a teoria em questão.
Ukraine and the Challenges of Post-Totalitarian Transit (1990-2019)
Authors:   Institute of History of Ukraine NASU, Holovko Volodymyr , Yakubova Larysa ,   Institute of History of Ukraine NASU
Published: August 2021

The key problems of nation- and state-building are revealed in the concept of the chronotope of the Ukrainian “long twentieth century,” which is a hybrid projection of the “long nineteenth century.” An essential feature of this stage in the history of Ukraine and Ukrainians is the realization of the intentions of socioeconomic, ethnocultural and political emancipation: in fact, the end of the Ukrainian revolution, which began in the context of World War I and the destruction of the colonial system. The third book tells about the contradictions of post-Soviet transit. The three modern revolutions, the development of “oligarchic republics,” the subjectivization of Ukraine in the world through self-awareness of the European choice are visible manifestations of the final stage of the century-old Ukrainian revolution and anti-colonial liberation war. The essential transformations of the Ukrainian project are understood in the broad optics of post-totalitarian transit, the successful completion of which now rules for the national idea of Ukraine. For a wide audience.
La salud mental durante la pandemia por COVID-19
Authors: Rodríguez-Gama Álvaro
Published: August 2021

La COVID-19 es una enfermedad infecciosa causada por el nuevo coronavirus SARS-CoV-2 y que desde su aparición en diciembre de 2019 ha tenido un impacto mundial al infectar a millones de personas y causar miles de muertes; esta entidad también ha dejado una gran cantidad de secuelas, tanto físicas como mentales, en las personas que han sobrevivido a sus fases graves.1,2 En la actualidad, Colombia es uno de los países que más se ha visto afectado por este cataclismo pandémico.
Publicación de los trabajos presentados en las ediciones 2016 y 2018 del Evento Científico Estudiantil Nacional de Medicina Interna - MEDINTÁVILA
Authors: Corrales-Reyes Ibraín Enrique , Hernández-García Frank , Pérez-García Enrique Rolando , Sorí-Peña Juan Antonio , Góngora-Gómez Onelis , Mejía Christian Richard
Published: August 2021

Introducción. Muchas de las investigaciones desarrolladas por estudiantes y presentadas en eventos científicos no se publican en revistas científicas.
Objetivo. Caracterizar los trabajos presentados en las ediciones 2016 y 2018 del Evento Científico Estudiantil Nacional de Medicina Interna (MEDINTÁVILA) y los publicados en revistas científicas, así como identificar los factores asociados a su publicación.
Materiales y métodos. Estudio transversal analítico. Mediante una estrategia de búsqueda realizada en abril de 2020 en Google Académico, se constató si los trabajos presentados en 2016 y 2018 en el evento habían sido publicados, en inglés o español, en revistas científicas. Se realizaron análisis bivariados para determinar si hubo características de los trabajos asociadas con su publicación, calculándose razones de prevalencia, junto con sus respectivos intervalos de confianza al 95% y valores p mediante modelos lineales generalizados (familia Poisson, función de enlace log) en los que se usó como clúster a cada universidad que presentó la investigación. Se consideró un nivel de significancia de p≤0.05.
Resultados. De los 335 trabajos analizados, 180 (53.73%) correspondieron a la edición de 2016. Respecto a la tipología y temática, 190 (56.72%) fueron clasificados bajo la categoría temas libres y 170 (50.75%) abordaron enfermedades crónicas. Se publicaron 24 (7.16%) trabajos, de los cuales solo nueve fueron citados, y en 19 (79.17%) hubo cambios de autores. No se identificaron factores asociados a la publicación de los trabajos en el análisis bivariado.
Conclusión. La publicación en revistas científicas de los trabajos presentados en ambas ediciones del MEDINTÁVILA es muy baja, por lo que es necesario que las universidades cubanas brinden más apoyo en investigación a los estudiantes de ciencias médicas, ya que esto podría aumentar las probabilidades de publicación de sus trabajos.
Lei de Diretrizes e Bases da Educação Nacional
Authors: Colomby Renato Koch , Gemelli Catia Eli , Oltramari Andrea Poleto
Published: August 2021

Compreendida como um marco regulatório da educação escolar, a Lei de Diretrizes e Bases da Educação Nacional (LDB) também pode ser fonte de interesse e reflexão para diversas outras áreas, como as que se dedicam às relações de trabalho. Pelo seu caráter inerente à atividade humana e às relações sociais, educação e trabalho são dimensões indissociáveis que se constituem historicamente, acompanhando as transformações econômicas, políticas e sociais. Dessa forma, este ensaio discute as aproximações entre os campos de estudos de educação e trabalho e reflete como a LDB também pode ser fonte de interesse para as pesquisas no campo das relações de trabalho.
Filosofia para crianças - avanços e desafios atuais: uma revisão sistemática de literatura
Authors: Faria de Souza Mayara
Published: August 2021

O programa Filosofia para Crianças (FpC) é uma proposta educacional desenvolvida por Matthew Lipman e Ann Shapp (1990), a qual tem como finalidade principal desenvolver nas crianças a capacidade de pensarem por si mesmas. Nesse contexto, foi conduzida uma revisão sistemática de literatura com foco no âmbito do programa FpC no Ensino Fundamental anos iniciais, com o objetivo de descrever os principais avanços e desafios atuais nessa área. A busca compreendeu o período de 2018 a 2020, sendo que, de 153 artigos retornados, 26 estudos compuseram esta revisão. Os resultados revelaram que os principais avanços são a importância das comunidades de investigação, a relevância do trabalho com FpC ainda nos primeiros anos de escolarização e a necessidade de uma condução eficiente no processo de elaboração dos questionamentos para as sessões do programa FpC. Os desafios compreendem sobretudo a figura do professor, e os obstáculos enfrentados por eles na aplicação do programa FpC.
Mechanical characterization and numerical modeling of laser-sintered TPE lattice structures
Authors: Kummert Christina , Schmid Hans-Joachim , Risse Lena , Kullmer Gunter
Published: August 2021

Additive Manufacturing provides the opportunity to produce tailored and complex structures economically. The use of lattice structures in combination with a thermoplastic elastomer enables the generation of structures with configurable properties by varying the cell parameters. Since there is only little knowledge about the producibility of lattice structures made of TPE in the laser sintering process and the resulting mechanical properties, different kinds of lattice structures are investigated within this work. The cell type, cell size and strut thickness of these structures are varied and analyzed. Within the experimental characterization of Dodecahedron-cell static and cyclic compression tests of sandwich structures are focused. The material exhibits hyperelastic and plastic properties and also the Mullins-Effect. For the later design of real TPE structures, the use of numerical methods helps to reduce time and costs. The preceding experimental investigations are used to develop a concept for the numerical modeling of TPE lattice structures.

Graphic abstract
Brasil na primeira página: uma análise da cobertura dos sites dos principais jornais da América do Sul sobre a eleição de Jair Bolsonaro em 2018
Authors: Ritter Eduardo
Published: August 2021

A eleição de Jair Bolsonaro para a presidência do Brasil em 2018 repercutiu no mundo inteiro. Importantes veículos, como The Economist e The New York Times, dedicaram um espaço nobre para o acontecimento político. Neste artigo, no entanto, o foco está na cobertura feita pelos sites dos principais jornais da América do Sul que falam língua espanhola logo após o anúncio do resultado do pleito. Para tanto, foram selecionados nove jornais de diferentes países que tiveram seus textos analisados através da Análise de Conteúdo, de Bardin (2011). Observou-se que, apesar da variedade de temas que se relacionam ao contexto, a Jair Bolsonaro e ao Partido do Trabalhadores, os textos tiveram mais semelhança do que diferenças na maneira como trataram o assunto, mostrando que o sul da América Latina – mesmo sem muito diálogo entre seus povos – seguem caminhos relativamente semelhantes, inclusive, no jornalismo.
O tribunal midiático e a construção do desengajamento moral pelo programa policial Patrulha da Cidade
Authors: Meirinho Daniel , Carvalho Denise
Published: August 2021

O artigo tenta compreender a percepção geral de um grupo de telespectadores sobre o programa policial Patrulha da Cidade, no Rio Grande do Norte, bem como a construção dos seus posicionamentos em torno da violência, segurança pública, justiça e direitos humanos. O objetivo busca refletir sobre os estímulos que levam os indivíduos a reproduzirem discursos de intolerância direcionados aos sujeitos que ameaçam a ordem social num tribunal midiático criado pelo programa, a partir do aporte teórico do desengajamento moral. A partir de entrevistas semiestruturadas esta pesquisa analisa as cumplicidades na construção do discurso moral da audiência a partir dos modos de endereçamento do programa.
A vanguarda está no rádio: cultura e engajamento na São Paulo da virada 70/80
Authors: Vicente Eduardo
Published: August 2021

A intenção desse artigo é refletir sobre o momento de efervescência cultural e abertura política que teve lugar no país na virada das décadas de 1970/1980. Ele é visto a partir da cidade de São Paulo e numa perspectiva que busca privilegiar o papel das emissoras de rádio nas estratégias de atuação de produtores independentes, especialmente daqueles vinculados às áreas de música popular e teatro. Assim, pretendemos tanto chamar a atenção para esse importante momento da história recente do país quanto destacar o papel então ocupado pelo rádio, buscando refletir sobre as possibilidades e limites da produção cultural independente num cenário de forte concentração econômica dos meios de difusão.
Authoring Ethnicized Subjects: Rigoberta Menchú and the Performative Production of the Subaltern Self
Authors: Arias Arturo
Published: August 2021

The debate over Rigoberta Menchú's testimonio has centered on whether or not Menchú told the “truth” regarding details of her personal life. According to her critics, her “lies” discredit her testimony and reduce the moral authority of leftist intellectuals who teach testimonial texts. This focus on verifiable facts ignores the literary value of testimonios in general and the importance of Menchú's testimony in particular in a discursive war tied to cold war politics. This essay explores the problematics of truth, the nature of testimonio as a genre, and the relation between political solidarity and subaltern narrative. It also examines the function of Menchú's testimonio as a discourse on ethnicity and considers the relation among the anthropologist, the subaltern subject, and truth. The conclusion deals with the need to rethink the concept of identity, with the desires and fantasies of subjective transformation, and with the notion of identity politics.
Collaboration and Concepts of Authorship
Authors: Carringer Robert L.
Published: August 2021

It was not long ago that one prefecture of french culture was reinventing the idea of authorship while another one was trying to kill it off. The New Wave movement and post-structuralism, fundamental opposites in almost every respect, emerged at the same cultural moment. Roland Barthcs's Writing Degree Zero (1953) and François Truffaut's seminal essay in Cahiers du cinéma that instated auteur criticism (the first phase of the New Wave) appeared less than a year apart; the appearance of Michel Foucault's Madness and Civilization (1961) coincided with the triumph of New Wave filmmaking; and in the interval between 1966 and 1970, which saw the publication of The Order of Things, Of Grammatology, and S/Z, Jean-Luc Godard, the most iconoclastic of the New Wave critic-directors, released fourteen feature films, including four masterworks. In its classic phase poststructuralism was fixated on the written word, involved disciplined thought inflected by mainstream Continental philosophy, took on itself the burden of refashioning modern European history along Marxist lines, and could be uncompromisingly rectitudinous. The New Wave spoke the language of images, involved a loose and—except for its radical stylistics—rather tame avant-gardism, valued an aleatory, free-form aesthetic over political commitment, assailed mainstream French culture, and championed alternative forms of cultural production such as American popular movies. Yet the teleologies were similar: to inscribe a unique place in the history of authorship. To supplant the biographical author from the textual site, one of the primary motives of poststructuralism, was to make the collective space available for a higher entity, the philosopher-critic who is the author not of individual texts but of textuality, the social meaning of texts. In the same way, in claiming the textual site for a film author—a radical conception for the time—the auteur critics scripted a role for themselves that they would subsequently occupy as film directors.
Developments in Foreign Approval Buying
Authors: Cohen Martin
Published: August 2021

“You claim to be entirely able to do your book selection with only a few suggestions from us here and there—how can that be'?” Thus Professor X to Librarian Y, all over North America. Well, granted, we librarians are proud of the subject know-how that we've acquired, some by earning higher degrees in the subject, others by just having learned our way around the literature of the subject after years in the trenches. We have to admit, though, that approval-plan buying has made a big difference: the vendor allows you to see the book before you decide whether or not to add it to the collection. (People do this when they buy a car or a cabbage; why not a book?) Approval-plan buying is a great deal more reliable than the reading of blurbs, which are all too often deliberately uninformative, or than waiting for reviews before ordering, which takes too long. However, since debate springs up from time to time about whether libraries with straitened budgets can afford approval plans (a red herring, in my view), I thought I'd speak up in defense of them, especially in my area, foreign language book selection.
Collaboration and Concepts of Authorship
Authors: Inge M. Thomas
Published: August 2021

Despite efforts among recent critical theorists to remove, banish, or even kill the author, the author remains at the center of general critical attention. It is commonplace now to understand that all texts produced by authors are not the products of individual creators. Rather, they are the result of any number of discourses that take place among the writer, the political and social environments in which the writing occurs, the aesthetic and economic pressures that encourage the process, the psychological and emotional state of the writer, and the reader who is expected to receive or consume the end product when it reaches print. Even if not intended for an audience or the publishing marketplace, a piece of writing cannot escape the numerous influences that produce it. All discourse is socially constructed.
Beyond the Question of Authenticity: Witness and Testimony in the Fragments Controversy
Authors: Bernard-Donals Michael
Published: August 2021

The publication of Binjamin Wilkomirski's Fragments in 1995 and the subsequent controversy over its authenticity can be seen as an object lesson in the vexed relation of history and memory. The book's status as an authentic memoir of the Holocaust has been impeached, yet Fragments may nonetheless be a useful vehicle for memory Cathy Caruth's and Shoshana Felman's work on trauma and on its relation to testimony indicates that testimony bears at best a tenuous relation to the events that form its core, particularly when the events are traumatic. An examination of Wilkomirski's language, read alongside (other) survivor testimony, suggests that Fragments may testify to a disaster other than the Holocaust. This conclusion, however, has controversial implications: that we need to reevaluate seriously how we treat testimony as historical evidence, including testimony of the Holocaust, and that the injunctions attached to Holocaust memory—never forget, never again—may be difficult if not impossible to heed.
A Convenience of Marriage: Collaboration and Interdisciplinarity
Authors: Hutcheon Linda , Hutcheon Michael
Published: August 2021

At the risk of sounding like a parody of a conversation about opera and illness in the 1987 movieMoonstruck, we would like to relate a postperformance dialogue about Richard Wagner's last opera.Parsifal(not Giacomo Puccini'sLa Bohème, as in the film). While descending the same staircase at the Metropolitan Opera in New York as Loretta and Ronny, the film characters played by Cher and Nicholas Cage, a man turned to his wife and said, not “You know, I didn't think she was going to die! I knew she was sick,” but “Do you think audiences today understand that Amfortas had syphilis?” Since this man is a physician, his wife was used to his medical observations, though this time he took her by surprise: “Syphilis? He was wounded by a spear when caught in the arms of the seductress Kundry!” “Yes,” he replied, “but that might just be Wagner's indirect or allegorical way of invoking nineteenth-century obsessive worries about venereal disease. Did you notice that this is a wound (one inflicted in a moment of amatory indiscretion) that won't heal, whose pain is worse at night and is eased only slightly by baths and balsams? To any nineteenth-century audience these symptoms and signals would have meant only one thing: syphilis.” “If that's the case.” his wife suggested, “then people must have written about this and we can find out.” “Not necessarily. People didn't talk openly about this kind of disease; it was secret and shameful, remember. And today, thanks to the discovery of penicillin, we luckily don't have to know about such things anymore,” said he.
Contribution of physical education classes to daily physical activity levels of adolescents
Authors: Sanz-Martin Daniel , Ruiz-Tendero Germán , Fernández-García Emilia
Published: August 2021

Introduction: Although practicing physical activity according to recommendations has health benefits, many studies have reported that the level of participation is lower than recommended. Methods: In this behavioural epidemiological study, we used a correlational design to determine the contribution made by physical education (PE) classes to daily physical activity in a sample of 694 Spanish adolescents. Physical activity levels were determined using the Four by One-Day Physical Activity Questionnaire. Results: 65.1% of adolescents comply with the recommendations on PE school days, compared to 36.6% who do so on the days with no PE class. Moreover, on PE school days, they obtain significantly higher physical activity level scores compared to days with no PE class. Conclusion: The study, therefore, shows the fundamental role of PE in increasing daily physical activity levels. Proposals to improve physical activity levels in these adolescents should be put forward, with educational centres being one of the best settings to achieve this goal.
Stats Entertainment: The Legal and Regulatory Issues Arising from the Data Analytics Movement in Association Football. Part Two: Data Privacy, the Broader Legal Context, and Conclusions of the Legal Aspects of Data Analytics in Football
Authors: Flanagan Christopher A.
Published: August 2021

Data analytics has become a critical part of professional football.  It brings with it a number of challenging legal questions, brought into sharper focus by the reported ‘Project Red Card’ legal action, in which the legality of the systematised use of player performance data has been called into question.  Focussing on the position in English law, this two-part article first considers whether the data produced in football is capable of ownership, whether in its raw format or after manipulation.  Next, the position in respect of data protection law (including FIFA’s Data Protection Regulations) is considered.  Finally, some broader legal issues are considered, including competition law and the regulation of artificial intelligence.Part One of this article set out contextual information on the development of data analytics in football, before examining whether the data produced in football are capable of ownership, either in raw format or after manipulation, taking into account the nature of property and intangible assets, relevant intellectual property laws and non-IP protections.Part Two considers the position in respect of data protection law (including FIFA's Data Protection Regulations).  Finally some broader legal issues are considered, including competition law and the regulation of artificial intelligence.The conclusions of Part One and Part Two together are that the intellectual property rights position is broadly positive for data analysts, with legal protections capable of application in may circumstances.  However, data protection law presents a more complicated problem, with a number of challenging compliance obligations for the analytics community, albeit with scope to exploit player performance data where those obligations are met.
Between cathedral and monastery: Creating balance between a pastor’s personal faith and public role
Authors: Langerman Peter David
Published: August 2021

The journey to ordination begins with justification, in which the disciple experiences faith, hope and love in the midst of the Triune God. What follows is a process by which the Christian disciple learns what it means to be conformed to the likeness of Christ, who is prophet, priest, and king. Christ’s on-going ministry has relevance to the church because in Christ’s exaltation and Christ’s spiritual presence in the church, Christ continues to lead the church as king priest and prophet. The church is called to live out the real presence of Christ in its midst and the ordained leader has a significant role to play in helping the church to do this.
African Biblical Interpretation of Matthew 20:1-15 in relation to social justice for workers in Cameroon
Authors: Van Eck Ernest , Ntem Godlove S
Published: August 2021

After the colonial era in the early sixties, the practice of employing and paying workers in Cameroon both in the civil service and in the private sector became very crucial, considering the fact that the situation of unemployment is so endemic to Cameroon as a paradigm for Africa’s unemployment. From an economic perspective, Cameroon has a booming labour force, but this robust manpower has been underutilized due to the provocative unemployment that is experienced in all sectors in the country. As an agrarian economy, the weakness of industrialization in Cameroon does not offer mass employment alternatives. Those who have the privilege to be employed are not satisfied with their remunerations to the extent that they try to use unorthodox means to add to their pay through corruption. This article highlights the desperate nature of Cameroonian workers through the lenses of Matthew 20:1-15. It is a society of unfair distribution of resources and this creates an imbalanced society between the privileged and non-privileged peasantry.
Volkskerk van Afrika en eerwaarde J.J.H. Forbes se teologie van antidiskriminasie, selfhelp en opvoeding
Authors: Katts Donald
Published: August 2021

The Volkskerk van Afrika and Reverend J.J.H. Forbes' theology of anti-discrimination, self-help, and educationThis article wishes to analyse the key elements in the theology of the founder and first minister of the Volkskerk van Afrika, especially as regards anti-discrimination, self-help, and education. In order to understand the theology of Forbes, it is necessary to portray the historical rise of the Volkskerk van Afrika as a Christian Church with special reference to the circumstances surrounding the establishment of the Church in 1922. Thirdly, it is intended to discuss the relevance of the Volkskerk van Afrika for today.
Gövde Borulu Isı Değiştiricilerinde Farklı Tip Şaşırtma Levhalarının Isı ve Akış Analizi
Authors: KARATAŞ Tuğçe , AKSOY İshak Gökhan
Published: August 2021

Gövde – boru tipi ısı değiştirici tasarımları hem analitik yöntemlerle hem de hesaplamalı akışkanlar dinamiği (HAD) yazılımları ile sayısal olarak yapılabilmektedir. Bu çalışmada model olarak küçük boyutlardaki gövde – boru tipi bir ısı değiştirici tasarlanmıştır. Modellemede bir gövde, bir boru geçişli ısı değiştirici kullanılmıştır. Yapılan çalışmada gövde içindeki boruların yüzey sıcaklığı sabit kabul edilmiş, sadece gövde tarafı akış analizi gerçekleştirilerek, ısı taşınım katsayısı ve akış özellikleri incelenmiştir. Farklı şaşırtma levha tipleri, akış hızları, türbülans modelleri, ağ boyutları kullanılarak gövde tarafı basınç düşümleri ve ısı taşınım katsayıları için ANSYS Fluent programında HAD analizleri yapılmıştır. Tek parçalı şaşırtma levhaları için elde edilen sayısal sonuçlar Kern analitik yönteminden elde edilen sonuçlarla karşılaştırılmıştır. Tek parçalı, disk ve halka şeklindeki şaşırtma levhası kullanılan gövde – boru tipi ısı değiştiricisinin ısı taşınım katsayısı ve basınç düşümü incelenmiştir. Ağ yapısının ısı transferine olan etkisi incelenip sıkı ağ yapısının daha iyi sonuçlar verdiği görülmüştür. Türbülans modellerinin karşılaştırılmaları yapılıp daha iyi sonuç veren k-ε türbülans modeli diğer analizlerde kullanılmıştır.
Zeolit Katkısının Antibakteriyel ve Kendi Kendini Temizleyen Harç Özeliklerine Etkisi
Authors: GÜLDAŞ Murat , CANBAZ Mehmet , ORHAN Mehmet
Published: August 2021

İnşaat sektöründe son yıllarda yapılan çalışmalarda yapıları sağlık açısından daha güvenli hale getirmek için yapı malzemelerine antibakteriyel özellik kazandırılması ve dış mekândaki korunmasız olarak dış etkilere maruz kalan yapı malzemelerine ışık etkisiyle kendi kendini temizleme yeteneği kazandırılması hedeflenmiştir. Bu çalışmada beyaz ve gri çimento ile üretilen harçlara antibakteriyel özellik kazandırmak amacıyla gümüş iyonları içerikli antibakteriyel toz ve antibakteriyel özellikli sıvı mergal, kendi kendini temizleme özelliği kazandırmak için anataz ve rutil fazında titanyum dioksit tozu, iyon değişimini kolaylaştırmak için zeolit farklı oranlarda ilave edilmiştir. Karışımlardan alınan numuneler üzerinde birim ağırlık, ultrases geçiş hızı, eğilme ve basınç dayanımı deneyleri yapılmıştır. İlave edilen katkıların fiziksel ve mekanik özeliklere etkileri belirlenmiştir. İtalyan standartlarına göre kendi kendine temizleme deneyleri ve Amerikan standartlarına göre antibakteriyel etkinlik deneyleri yapılmıştır. Yapılan deneyler sonucunda ilave edilen katkıların harçların fiziksel ve mekanik özeliklerine olumsuz etkileri olmadığı, titanyum dioksit tozunun kendi kendini temizlemede etkili olduğu ve antibakteriyel katkıların ise bakterilere karşı etkili bir şekilde kullanılabileceği görülmüştür.
Harran Ovası Yaygın Toprak Serilerinin Su Tutma Eğrilerinin Belirlenmesi
Authors: ÖZTÜRKMEN Ali Rıza , RAMAZANOĞLU Emrah , ÇAKMAKLI Murat , ÇAKMAKLI Eda
Published: August 2021

Harran Ovası toplam 225 000 hektarlık büyük bir tarımsal potansiyele sahiptir. Bu araştırmada, Harran Ovasında yaygın olan toprak serilerinin su tutma eğrilerinin belirlenmesi amaçlanmıştır. Çalışmadan elde edilen veriler ve tartışmaların ışığı altında, Fatik ve Tektek dağları rezidüleri ve ova topraklarının kil mineralleri bakımından gösterdiği benzerliğe dayanarak, paligorskitin kireç taneleri içinde oluştuğunu ve bunun ayrışma sonucu toprağa karışmakta olduğu söylenebilir. Toprakta suyun tutulma basıncı bitkilerin toprak suyundan faydalanmasını direkt etkilemektedir. Bu çalışmada Harran ovasında Harran, Çekçek, Bellitaş ve İkizce olmak üzere 5 adet toprak profili açılmıştır. Toprak profillerinde yapılan tarla kapasitesi, daimi solma noktası ve yarayışlı su içerikleri analizlerinde toprakların birbirine yakın değerler belirlenmiştir. Toprak profilleri saturasyon yüzdesi ortalama değer olarak Çekçek seri %70,86, Harran 1 serisi %82.19, Harran 2 serisi %81.73, İkizce serisi %65.23 ve Bellitaş serisi 67.43 olarak belirlenmiştir. Harran Ovası topraklarının ağır bünyeli topraklar olduğu ve tarla kapasitesi bakımından ise yüksek olarak belirlenmiştir.
The Effects of Coriandrum sativum L. and Chaerophyllum macropodum Boiss. (Apiaceae) on human plasma angiotensin-converting enzyme (ACE) in vitro
Authors: ÇELİKEZEN Fatih Çağlar , TÜRKOĞLU Vedat , FIRAT Mehmet , BAŞ Zehra
Published: August 2021

Hypertension is a very important problem around the world. The inhibition of the Angiotensin-converting enzyme (ACE, EC.3.4.15.1.) is regarded as fundamental of hypertension treatment. But, synthetic ACE inhibitors have several side effects. For this reason, there are lots of studies to improve green ACE inhibitors. Therefore, this study was designed to determine the potential inhibitory effects of two members of Apiaceae, Coriandrum sativum and Chaerophyllum macropodum, on human plasma ACE. Fort this purpose, water extracts of the plants were used. ACE inhibition activity was detected spectrophotometrically. Both plant extracts showed an inhibitory effect on ACE activity. The obtained results showed that Coriandrum sativum and Chaerophyllum macropodum have inhibitory effects on human plasma ACE with an IC50 value of 0.7 mg/mL and 1.14 mg/mL, respectively. Lineweaver-Burk graph was used to determine the inhibition type. The inhibition types were found as reversible noncompetitive. According to the obtained results, Coriandrum sativum and Chaerophyllum macropodum are valuable functional food with ACE inhibition capacity which may be used to balance blood pressure efficiently.
Pathological syndromes of the biliary tract decompression
Authors: Mejidov Rasul T. , Magomedova Saadat , Mamedova Elmira P. , Abdullaeva Asli Z. , Nasibova Umukusum A.
Published: August 2021

Background: The increased incidence of cholelithiasis and tumoral lesions of the hepatopancreatoduodenal zone leads to an increase in the number of patients with obstructive cholestasis.
Aims: To identify the spectrum of pathological conditions developing after decompression of the biliary tract in obstructive cholestasis and to develop an effective pathogenetically determined algorithm for treating patients.
Methods: The results of the examination and treatment of 216 patients with obstructive cholestasis, who underwent various options for decompression of the biliary tract, were analyzed. Obstructive cholestasis of a tumor genesis was present in 112 (51.8%) patients, benign cholestasis in 104 (48.2%). The main group included 112 patients, the comparison group included 104 patients. A two-stage tactics was applied in 133 (61.6%) cases, 83 patients (38.4%) were operated in one stage. The treatment results were compared for the experimental group (n=112) in which a pathogenetically based algorithm was applied and for the control group (n=104) receiving a standard therapy.
Results: Accelerated decompression syndrome developed in 31 (14.3%) cases, of those 26 in the comparison group, 5 in the main group. Disorders of the water and electrolyte balance occurred in 32 (46.4%) patients with complete external bile diversion. Digestion remodeling syndrome was present in 44 patients from 117 patients with external bile diversion.
Conclusions: It has been shown that the pathogenetically based therapy after biliary decompression significantly reduces the number of complications in the postoperative period.
Validation of Fault Displacements from Dynamic Rupture Simulations against the Observations from the 1992 Landers Earthquake
Authors: Wang Yongfei , Goulet Christine
Published: August 2021

Coseismic fault displacements in large earthquakes have caused significant damage to structures and lifelines on and near fault lines. Coseismic displacements represent a real threat, especially to distributed infrastructure systems. For infrastructure systems that can not avoid active faults, engineering displacement demands are defined using probabilistic fault-displacement hazard analyses (PFDHA). However, PFDHA models are sparse and poorly constrained partly due to the scarcity of detailed fault-displacement observations. Advancements in dynamic rupture simulation methods make them an attractive approach to address this important issue. Because fault displacements can be simulated for various geologic conditions as constrained by current knowledge about earthquake processes, they can be used to supplement the observation datasets. In addition to providing on-fault displacements, when used with appropriate constitutive models for the bulk medium, they can capture off-fault distributed inelastic deformations as well. For viable extrapolation, simulations must first be validated against data. In this article, we summarize the calibration and validation of the dynamic rupture model against the observations of the well-documented 1992 Landers earthquake. We defined a preferred model that reproduces several first-order fault-displacement metrics such as the on-fault partition of the total displacement, the mean fault-zone width, and the location of the peak displacement. Simulated ground motions consistent with the observations ensure that all physics important to modeling have been properly parameterized. For the extrapolation, we generated a suite of dynamic rupture models to quantify expected fault-displacement metrics, their intercorrelations, and magnitude dependencies, which are in part supported by the Landers and other recent earthquakes. Our validation and extrapolation exercise paves the way for using dynamic rupture modeling to quantitatively address fault-displacement hazard on a broader scale. The results are promising and are expected to be useful to inform PFDHA model development.
Exploring Entrepreneurial Students' Perceptions of Online Mindful Creativity Training
Authors:   , Schmitz Melissa , Lyttle Constance
Published: August 2021

Postsecondary education that supports the development of creativity is a recent and developing phenomenon. This emerging literature required research on effective elements and best implementation practices for creativity education at all levels including institutions of higher education (IHE). Mindful Creativity (MC) is a three-module, asynchronous, online, creativity training program designed to deliver postsecondary instruction on mindfulness, creativity, and applied neuroscience to support creativity development across all IHE disciplines. Each 90-minute MC training module-Mindfulness, Creativity, and Mindful Creativity for Education and Work-is designed to support dispositional mindfulness and creativity by conceptualizing both in neuroscience. This research study utilized a convergent, mixed-methods case study design to examine how postsecondary entrepreneurial students perceived and experienced the impact of a MC training program. Quantitative data related to participants' mindfulness mindsets were collected from the Mindful Attention Awareness Scale (MAAS). Data related to participants'creativity mindsets were collected from the Reisman Diagnostic Creativity Assessment (RDCA). Qualitative data were collected from course assignments, artifacts, and semi-structured interviews. The researcher analyzed quantitative pre- and post-test survey data from the MAAS and the RDCA and conducted additional data analyses after merging the quantitative data with qualitative data to understand the impact of the MC training program. The results demonstrated the effectiveness of utilizing a combination of mindfulness, creativity, and applied neuroscience as elements of creativity training for postsecondary students. Participants reported the MC training program provided a transformational learning experience by supporting mindfulness and creativity in three ways: (a) MC training enhanced self-confidence of creative attributes and the ability to articulate creative strengths, (b) MC training supported a creative mindset and the awareness needed to realize opportunities to improve critical and creative thinking, and (c) MC training supported application of learning that provided a path for sustainable creative growth. These findings support creativity training that includes instruction in mindfulness, creativity, and applied neuroscience as effective elements to support postsecondary students' creativity development.
A Case of Heart Transplantation after Ischaemic Preconditioning
Authors: Micallef Eynaud Steve , Sladden David , Manche Alexander
Published: August 2021

A case of successful heart transplantation from a donor that suffered an out of hospital cardiac arrest lasting approximately one hour is presented. The recipient, a 27-year-old female nurse, was diagnosed with arrhythmogenic right ventricular cardiomyopathy in 2012. The donor was a 24-year-old male who after consuming an unknown quantity of alcohol and cocaine aboard a yacht was found floating face-down in the sea. The patient to be pulseless and CPR commenced after 7 minutes. The length of time that he spent in the sea was unknown. Return of spontaneous circulation (ROSC) occurred after 20 minutes of CPR on site. However, the patient arrested again in the ambulance and CPR was performed until he arrived Hospital, still in cardiac arrest. The patient arrested three more times before achieving a stable circulation. He was transferred to the intensive care unit on high doses of Noradrenaline and Adrenaline to maintain an adequate mean arterial blood pressure. An initial echocardiogram (ECHO) revealed a hypocontractile left ventricle (LV) with an estimated ejection fraction (EF) of 30%.Over the following 3 days the patient’s cardiac function improved. He was  weaned off inotropic support and a repeat ECHO showed a normal LV with an EF of 70%. A brain MRI showed diffuse swelling consistent with global hypoxic injury with wide areas of cortical and basal ganglia infarction. The patient’s parents gave their consent and he was offered for organ transplantation on day 6. The operation was successful, with the recipient making an uneventful recovery. She received immunosuppressive treatment with cyclosporine, prednisolone and azathioprine and experienced one episode of early mild rejection with full resolution. She remains well 8 months later.
Cutaneous Manifestations of Infective Endocarditis
Authors: Cortese Francesca , Di Marino Serena
Published: August 2021

Despite advances in diagnosis and treatment, infective endocarditis still shows considerable morbidity and mortality rates. The dermatological examination in patients with suspected infective endocarditis may prove very useful, as it might reveal suggestive abnormalities of this disease, such as Osler’s nodes and Janeway lesions. We report a case of a women with infective endocarditis and the typical cutaneous manifestations. Despite advances in diagnosis and treatment, infective endocarditis still shows considerable morbidity and mortality rates. The dermatological examination in patients with suspected infective endocarditis may prove very useful, as it might reveal suggestive abnormalities of this disease, such as Osler’s nodes and Janeway lesions. We report a case of a women with infective endocarditis and the typical cutaneous manifestations.
Transformaciones de la investigación jurídica y sociojurídica en derecho en tres subregiones andinas de Colombia
Authors: Vásquez Santamaría Jorge Eduardo , Maya Zuluaga Marta Cecilia , Millán Otero Katy Luz
Published: August 2021

Based on the question ¿What transformations are present in legal and socio-legal research in the different territorial scales of Colombia in the 2008-2020 period?, these transformations are evidenced in the Andean region from the study of three subregions: Eje Cafetero, Santanderes, and Tolima Grande. A data hermeneutic was used based on a qualitative documentary study carried out on the information available in previous works and sources from the Ministry of Science, Technology, and Innovation (MinCiencias). The analysis and interpretation of the data made it possible to understand the state of consolidation of the groups, their qualification in code with the official guidelines established in the calls of the Ministry of Science, their production levels, and the thematic approaches that prevail in the three subregions. It was evidenced that in recent years a small number of research groups have been maintained in the subregions, however, growth experiences in Santander, Caldas, and Huila stand out, as well as the consolidation of a trend of work on new topics and products
Reparación del daño desde el enfoque diferencial de género: restablecimiento de derechos sexuales y reproductivos en la jurisdicción contencioso-administrativa
Authors: Pabón Mantilla Ana Patricia , González González María Alejandra , Viteri Aguirre Mary Genith
Published: August 2021

The article presented here encompasses a series of reflections derived from research conducted to ana-lyze measures granted to repair damages with a differential gender perspective; it uses as a reference an emblematic case solved within the Council of State of Colombia. With this objective, a critical review of documentary sources was conducted, to identify the categories of judicial thought that would later serve to analyze the discourse of the text of the sentence. The findings revealed the guiding theoretical and juris-prudential criteria of the Constitutional Court that should guide judicial activity when facing a case where gender matters. The case analyzed marks a milestone in the assessment of damage from a differential gen-der perspective, granting legal recognition to the fact that a negative impact on the sexual and reproductive rights of women generates serious damages in their lives. The conclusions reinforce the need to continue with the training process within the Judicial Branch to achieve transformative decisions that significantly affect the lives of women and girls who resort to the administration of justice in Colombia
La violencia intrafamiliar en el proceso de formación de los menores en Cartagena y sus repercusiones sociales
Authors: Noriega Ruiz Armando José , Noriega Saravia Silvana Sofía
Published: August 2021

This article was based on a documentary research that aims to analyze how domestic violence marks or influences the process of formation and development of the future citizen in order to raise awareness about the importance of preserving levels of respect which must exist within families. This article achieves a high social relevance because the problem that develops in it can occur in families of different social stratum or conditions. In other words, having the knowledge of the existence of this phenomenon is important in the family life of all households, since these behaviors and their effects do not distinguish religion, race, gender or social status. Moreover, the study of these acts allows us to understand even more the victimogenesis of domestic violence and the consequences that unfold from these situations. To this end, we will draw on the studies that exist on this issue at the global and national levels with an accentuated focus on the various reports that have been issued by governmental and non-governmental entities in the Cartagena district.
La confiscación de órganos a la luz del derecho constitucional a la protección de la salud
Authors: Moya Guillem Clara , Rodríguez-Arias David , Morla González Marina , Miguel Beriain Íñigo de , Molina Pérez Alberto , Ortega-Deballon Iván
Published: August 2021

En este trabajo analizamos los argumentos a favor y en contra del que hemos denominado modelo de obtención automática en relación con los órganos de fallecidos. Para ello aportamos datos empíricos que permiten valorar su potencial impacto en las cifras de donación y en la opinión pública. Específicamente, por un lado, examinamos las razones que lo respaldan, haciendo especial referencia a aquellas relativas a la utilidad y la justicia. Por otro lado, estudiamos las manifestaciones que se oponen a este modelo teórico fundadas en la vulneración de intereses pre mortem y post mortem, y en el rechazo que generaría en la población. Por último, a modo de conclusión, subrayamos los aspectos que, a nuestro juicio, deberían regularse exhaustivamente si se implantase. En particular, nos referimos al estatuto jurídico del cuerpo humano, al trato al paciente en la última etapa de su vida, a los incentivos para los profesionales sanitarios y al reconocimiento del derecho a la objeción de conciencia.