bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Organizational Commitment and Work Discipline on Employee Performance Using Work Environment as an Intervening Variable at PT. YKT Gear Indonesia During the Covid-19 Pandemic
Authors: Apriani Pipin Eka , Masydzulhak Djamil
Published: September 2023

The purpose of this study is to analyze the effect of organizational commitment, work discipline and work environment on performance and formulate strategies to improve performance during the Covid-19 pandemic by taking case studies at PT. YKT Gear Indonesia. a quantitative descriptive research design was used by the authors in 260 participants made up the sample of 160 respondents for survey. The Partial Least Squares approach is an analysis technique (PLS), Research results prove that (1) Organizational Commitment influences the work environment positively and significantly (2) Workplace environment is significantly and favorably affected by work discipline (3) Organizational commitment influences employee performance positively and significantly (4) Employee performance is positively and significantly impacted by work discipline. (5) Employee performance is positively and significantly influenced by the work environment (6) Organizational Commitment has a positively and significantly effect on employee performance through the work environment as an intervening variable (7) Employee performance is positively and significantly influenced by work discipline through the work environment. Suggestions and input for PT. YKT Gear Indonesia to be committed and paying attention to the workplace environment to encourage more discipline among staff, and can carry out their duties and obligations properly.
The Effect of Product Innovation on Customer Loyalty (Survey of Samsung Phone Users in Indonesia)
Authors: Supriatna Pepen Supriatna , Agus Rahayu  , Puspo Dewi Dirgantari
Published: September 2023

In the digital era, Samsung is a brand that dominates smartphones. This South Korean brand is the number one Android phone manufacturer recognized for its capabilities globally. Even though Samsung has the highest market share, Samsung's market share has decreased. The low customer loyalty is allegedly the main cause of the decline in Samsung's market share. This paper aims to determine product innovation's effect on customer loyalty for Samsung cellphone customers in Indonesia. The research method in this scientific work is carried out quantitatively. The sampling technique used was nonprobability, with purposive sampling as the sampling technique. Meanwhile, the number of respondents was 100 people who live in Indonesia and are Samsung cell phone customers. While the data analysis technique used is simple linear regression analysis. The results of this study reveal a positive influence of product innovation on customer loyalty for Samsung cellphone customers in Indonesia.
The Effect of Benefits, Convenience, Risk, Income on Purchase Decisions Using Shopee Paylater
Authors: Aprianto Jimmy Daniel , Hadibrata Baruna
Published: September 2023

A new digital payment system was developed as a result of the rapid development of technology and the internet in Indonesia. Financial technology (fintech) is one of the technological advances in the increasingly widespread Indonesian financial sector. The research was conducted with the aim of analyzing the relationship between perceived benefits, perceived convenience, risk, and income on purchasing decisions using a shopee paylater. The research model uses a causal research design. The population in this study are all customers who use the Shopee Paylater application in DKI Jakarta whose exact location is unknown. The technique used in selecting the sample is purposive sampling. By determining the criteria data, characteristics, and appropriate characteristics. The minimum number of samples in this study is 135 respondents. Researchers used IBM SPSS Statistics 26 software to analyze descriptive characteristics and SmartPLS 3.3 software to measure research data using the Partial Least Square (PLS) method. The results show that benefits and convenience have a positive and significant effect on purchasing decisions. However, risk and income have a positive but not significant effect on purchasing decisions
Determination of Management Decision Quality: Integration, Effectiveness, Development of Management Information Systems
Authors: Wulandari Sri , Hapzi Ali
Published: September 2023

The Influence of Integration, Effectiveness and Development on the Quality of Management Decisions is a scientific article in a literature study that aims to build a research hypothesis on the influence of variables to be used in further research, within the scope of Executive Support Systems For Business. The method of writing this article is the library research method, which is sourced from online media such as Google Scholar, Mendeley and other academic online media. The results of this article are that: 1) Integration has an effect on the Quality of Management Decisions; 2) Effectiveness influences the Quality of Management Decisions; and 3) Development influences the Quality of Management Decisions.
Good Corporate Governance: Transparency, Accountability, Responsibility, Independency dan Fairness (Literature Review)
Authors: Karsono Bambang
Published: September 2023

Literature Review Articles of Good Corporate Governance (GCG): Transparency, Accountability, Responsiblity, Independency and Fairness is a scientific articles literature review. The purposes of writing this article is to build a hyphotesis of influence or role between variables which will be used in further research, within the scope of Human Resource Management and Leadership. Article Writing Method is library research, sourced by online media such as Google Scholar, Mendeley and other academic online media. The results of this article are: 1) Transparency plays a role in making GCG; 2) Accountability plays a role in realizing GCG; 3) Responsibility plays a role in making GCG; 4) Independency plays a role in making GCG happen; and 5) Fairness plays a role in realizing GCG. Other factors that affect GCG including participatory, inclusive, and follow the rules.
The Performance of PT TA Assets Indonesia Employees is Influenced By The Provision of Salaries Through Job Satisfaction
Authors: Silitonga Eddy Sanusi
Published: September 2023

The purpose of this study was to analyze and determine the positive and significant effect of salary on employee performance through job satisfaction as an intervening variable at PT. TA Asset Indonesia. The subjects in this study were all employees of PT. TA Asset Indonesia using a quantitative approach method. Meanwhile, to analyze the pattern of relationships between variables in this study using path analysis with the aim of knowing the direct or indirect effect of a set of independent variables on the dependent variable. The results of this study state that there is a direct influence between salary on employee performance at PT. TA Asset Indonesia with going through job satisfaction.
Executive Support System For Business and Employee Performance: Analysis Of The Ease of Use Of Information System, User Satisfaction and Transformational Leadership
Authors: Parulian Ronald , Hapzi Ali  , Ni Nyoman Sawitri
Published: September 2023

This article aims to examine the relationship between various variables in order to identify potential solutions. The research method used is qualitative, involving the analysis of published journals. Out of the five factors reviewed, three are independent variables, namely the ease of use of information systems, user satisfaction with information systems, and transformational leadership. The executive support system for business is considered the intervening variable, while employee performance is the dependent variable. The analysis of twenty published journals concludes that the independent variables have a positive and significant impact on employee performance. The literature review suggests that businesses should take all factors into account to improve employee performance.
Keywords: Ease of Use of Information System, User Satisfaction, Transformational Leadership, Executive Support System for Business, Employee Performance
The Influence of Visionary Leadership, Organizational Culture, and Work Discipline on Employee Performance at SMP Negeri 1 Kedungwaringin
Authors: Mulyadin Aji , Hersona Sonny , Hartelina Hartelina
Published: September 2023

This study has purpose in determining the correlation between visionary leadership, organizational culture, and work discipline in influencing the performance of employees at SMPN 1 Kedungwaringin Bekasi Regency. This research method applies empirical quantitative research through verifiative descriptive approach. The population and sample used amounted to 64 respondents consisting of 59 teachers and 5 education staff. The results of this research indicate that visionary leadership, organizational culture, and work discipline had significantly positive effect on the performance of employee. In addition, vision leadership, organizational culture, as well as work discipline also had simultaneous effect on the performance.
Analysis of Fashion Value Chain Sustainability to Strengthen Added Value Through Entertainment Activities (Fashion Shows) syarifapd
Authors: Priani Dewi Syarifa , Sugeng Santoso
Published: September 2023

Fashion is a secondary human need that can change according to the times or someone's wishes which can be seen from language, habits to how to dress. The production of fashion products is inseparable from various value chain activities. The value chain is a collection of activities carried out by each company to design, manufacture, market, deliver, and support its product. The fashion value chain consists of design, production, marketing and distribution activities. Fashion is also a product of the creative economy which is a mainstay in the country. The potential for various fashion products in Indonesia is enormous, so it is necessary to develop various fashion products in Indonesia to strengthen their added value. This research is a quantitative study using MDS-RAPFISH analysis with a case study in Nganjuk Regency. The results of this study show that the sustainability status of the value chain in design activities, production processes and marketing shows a fairly good sustainability status. Meanwhile, the dimensions of distribution and entertainment activities show good sustainability. And the overall results of the MDS-RAPFISH show indications of improvement, except for the dimensions of marketing and entertainment activities.
The Influence of Organizational Culture and Work Environment on Employee Engagement Through Employee Resilience as Intervening Variable (Study on Strategic Management and Governance-Bank Indonesia)
Authors: Lombongadil Febrianty , Masydzulhak Djamil
Published: September 2023

The purpose of this study was to examine the influence of organizational culture and work environment through employee resilience as an intervening variable on employee engagement at Strategic Management and Governance Department - Bank Indonesia. The quantitative descriptive research design with 92 participants as sample of the study. This study used Partial Least Square (PLS) which is a covariance-based SEM  as an analysis tool. The result of this study showed that (1) organizational culture influences employee engagement positively and significantly (2) organizational culture has a positive and significant effect on employee resilience, (3) work environment influences employee engagement positively but not significantly (4) work environment influences employee resilience positively and significantly (5) Employee resilience has positive and significant effect on employee engagement (6) Employee engagement is positively and significantly influenced by organizational culture through employee resilience (7) Employee engagement is positively and significantly influenced by the work environment through employee resilience. The implementation of organizational culture and the work environment’s condition at Bank Indonesia must be improved. These variables also affect the level of employee engagement. The higher level of employee engagement will help the employee to complete the duties and obligations optimally and properly.
Recognizing Consumer Behavior from the Perspective of Continuance Intention Theory: A proposed framework
Authors: Reano Pandrika Parikesit Raphael , Permana Dudi
Published: September 2023

In recent decades, the level of internet usage, especially in Indonesia, has shown significant growth. This encourages the growth of the use of various applications, one of which is an online transportation application. GoRide service on the Gojek application is one of the applications that is often used. This study will examine the influence of perceived usefulness, satisfaction, attitude variables on the continuance intention of GoRide users on the Gojek application. The population of this study is all Gojek application users in the last three months in the Jabodetabek area with the sampling technique used is non-probability sampling with a minimum sample number of 170 respondents.  Furthermore, this research will use SEM PLS 4 in the data analysis process. The results of this research are in the form of a proposed framework that will be continued as empirical research.
ANALISIS RISIKO KREDIT, RISIKO PASAR DAN RISIKO LIKUIDITAS PADA BANK UMUM BUMN
Authors: Indrawan Ida Bagus Agung , Rikumahu Brady
Published: September 2023

Bank berfungsi sebagai intermediasi menghubungkan pihak yang mempunyai dana dengan pihak yang membutuhkan dana. Bank dalam menjalankan tugasnya mengelola banyak risiko, dengan risiko kredit, risiko pasar dan risiko likuiditas menjadi titik fokus penelitian. Studi ini mempelajari dan mengantisipasi risiko kredit, risiko pasar, dan risiko likuiditas dimasa mendatang pada empat bank umum BUMN yang tercatat di Bursa Efek Indonesia tahun 2010 hingga 2021 dengan menggunakan model ARIMA (Autoregressive Integrated Moving Average). Dapat disimpulan pada penelitian ini menunjukkan hasil yang beragam. Tidak sepenuhnya risiko pada perbankan dapat diprediksi dengan menggunakan ARIMA, karena ditemukan sebagian dari risikonya tidak dapat diprediksi dengan ARIMA.
Engineering Activity in the Context of Humanitarian Thinking
Authors: Sheinbaum V. S.
Published: September 2023

With the release of a package of state-level regulatory documents during the perestroika years, which set a new vector for the development of domestic education and, among other things, set the task of enriching the ideological, theoretical, humanitarian content of higher education, the reform of the country’s higher education began, which continues in waves to this day. The powerful flow of articles, reports, dissertations devoted to the humanization and humanitarization of engineering education, which has gushed since that time, does not weaken. The experiment has shown that artificial intelligence ChatGPT-4 generally gives an adequate idea of the current issues in this area of engineering pedagogy. In the article, for the first time, this task is projected on the formation of students’ engineering thinking of a humanitarian orientation, which is necessary to ensure their effectiveness in the labor market in especially cardinal changes in technology and the organization of engineering activities, used with an exponentially growing scale of the use of artificial intelligence and robotics in it. The idea is being developed that engineering thinking is inherently inseparable from the humanitarian one, which sets its direction, and the idea put forward by P.G. Shchedrovitsky’s hypothesis about programming as a dominant way of thinking of an engineer in an emerging new technological formation, which is based on goal setting with the subsequent design of an “activity tree” as a projection of a tree of goals. The purpose of the article is to substantiate the regularity of the organic strengthening of the humanitarian focus of engineering thinking in the course of the ongoing industrial revolution and the need to focus engineering pedagogy on this trend, based on the author’s proposed refinements of ontologically established ideas about engineering activities.
Instrumentalidade do processo e a dispensa de conciliação e instrução nos Juizados Especiais Cíveis
Authors: Ribas Daniel Stefani , Barros Mouro Vitória
Published: September 2023

O presente artigo tem como fito a possibilidade da dispensa de determinados atos processuais nos Juizados Especiais, partindo da concepção da instrumentalidade do processo de Cândido Rangel Dinamarco. A realização desse estudo está fundamentada em pesquisa bibliográfica, documental e jurisprudencial. Dentre as principais conclusões, está a possibilidade de mudanças nos procedimentos dos Juizados Especiais Cíveis para que ocorra uma maior celeridade. Por fim, conclui-se que a dispensa tanto da conciliação e da audiência de instrução nos Juizados Especiais é um caminho para um processo democrático que valoriza os direitos fundamentais, e o efetivo contraditório não sendo uma mera sensação de autocomposição como hoje.
Educação inclusiva
Authors: Neder Erika
Published: September 2023

A educação inclusiva é um conceito que busca garantir o acesso e a participação de todas as pessoas na escola e no processo de aprendizagem, independentemente de suas diferenças e limitações. A inclusão pressupõe que todas as pessoas têm capacidades, habilidades e talentos diferentes, e que essas diferenças devem ser respeitadas e valorizadas. A diversidade é uma característica fundamental da sociedade contemporânea, e a educação inclusiva valoriza essa diversidade, promovendo o respeito e a priorização das diferenças. As adaptações e recursos didáticos são fundamentais para garantir que todos os alunos tenham acesso ao conhecimento e às oportunidades de aprendizagem, independentemente de suas diferenças. O ensino colaborativo e a avaliação inclusiva são práticas pedagógicas que favorecem a inclusão e a aprendizagem de todos os alunos. A importância da educação inclusiva reside na possibilidade de criar um ambiente de aprendizagem mais rico e inclusivo, que reconhece e valoriza a diversidade e promove a igualdade de oportunidades para todos os alunos. Dessa forma, o estudo pretende demostrar a importância da educação inclusiva para o desenvolvimento humano, utilizando o filtro da teoria das capacidades de Nussbaum, e para isso, utiliza metodologia bibliográfica com revisão de literatura e documental por apresentar legislações sobre o tema.
The Case for Conscious Experience Being in Individual Neurons
Authors: Edwards Jonathan , Somov Pavel G
Published: September 2023

The idea that individual nerve cells might have conscious experiences has been around ever since cells were identified in the seventeenth century, but in the era of modern neuroscience the case for individual human neuronal experience has received little attention. A series of arguments will be presented suggesting that all the human conscious experiences that we talk about are events in individual neurons, not global to the brain or organism. We conclude that cellular consciousness is the only plausible way to explain ‘our’ experiences within current physics and biology, however implausible it might at first seem. This implies that our experiences are multiple in space as well as time, consistent with the neuroscience watchword that there is ‘no single place where everything comes together in the brain’. The central argument is that events of experience must involve rich integration of information and individual neurons are the only places in brains where integration of information occurs. Any more global ‘binding’ is neither required nor physically possible. The detailed nature of events of integration of signals in a neuron’s dendrites remains uncertain but recent developments provide some candidates.
The Impact of Macroprudential and Monetary Policies Instruments on the Private Credit Growth in the Arab Banking Sector
Authors: Obeid Rami
Published: September 2023

This paper investigates the potential impact of the macroprudential instruments, namely debt-to-income (DTI) ratios, the loan-to-value (LTV) on controlling the private credit growth in the Arab banking system, and we also attempt to examine the effects of the monetary policy instruments on private credit growth by using Generalized Method of Moments (GMM) technique. We measure the effect of loosening or tightening these instruments on the growth of the private credit using a sample covers ten Arab countries based on quarterly data for the period (2014-2019). The results reveal that the macroprudential policy tools have the power to control the private credit growth, as the effects of tightening the DTI and the LTV ratios appear directly after one quarter, while the change of the monetary policy tools and the required reserve ratio have a negative impact on the private credit growth, and their effects appear after two quarters and one quarter respectively. Finally, the results show that there is no evidence of significant impact of the economic variables on credit growth.
Road Tolling and Domestic Revenue Mobilisation in Zimbabwe
Authors: Chilunjika Alouis , Uwizeyimana Dominique E. , Chilunjika Sharon R. T.
Published: September 2023

The study analyses the effectiveness of road tolling-systems as an instrument for mobilising domestic revenue in Zimbabwe. The study assessed the effectiveness of road-tolling systems in mobilising revenue to recoup the costs of building, operating and maintaining road infrastructure. Revenue performance was rated using the internal and external dimensions of toll revenue, which revolve around activities such as toll revenue collection, administration (remittance) as well as the Zimbabwe National Road Administration’s (ZINARA’s) distribution and usage of the toll revenue. By way of mixed methods research design, the study conceptualised and contextualised the theory, models, technologies and practices of toll revenue collection in Zimbabwe. The study found that the Zimbabwean road tolling model as a hybrid conventional tolling model is a progressive, effective and reliable tool to raise revenue for constructing road infrastructure and related road-related capital investments in Zimbabwe and that the internal toll revenue performance is up-to-date with reduced toll revenue leakages and increased toll revenue yield. However, the study found that there is no meaningful investment on the road network and related highway infrastructure thus making the performance of external toll revenue questionable. The study recommended the strengthening of toll revenue collection, management, remittance and toll fees usage.
Prevalence of arrhythmias in elderly inpatients at department of cardiology of Thong Nhat Hospital
Authors:   Pham Ngoc Thach Univesity of Medicine, Ho Chi Minh City, Vietnam, Ho Dung Si , Trần Bách Quang ,   School of Medicine, Vietnam National University Ho Chi Minh City, Vietnam, Mai Hữu Bá Gia ,   School of Medicine, Vietnam National University Ho Chi Minh City, Vietnam, Đỗ Phúc Thị Mỹ ,   School of Medicine, Vietnam National University Ho Chi Minh City, Vietnam, Lê Phương ,   School of Medicine, Vietnam National University Ho Chi Minh City, Vietnam, Trần Trinh Bảo ,   School of Medicine, Vietnam National University Ho Chi Minh City, Vietnam, Nguyen Cong Duc ,   Thong Nhat Hospital, Ho Chi Minh City, Vietnam
Published: September 2023

Background: Arrhythmia is becoming an important condition of the elderly with high prevalence and frequency with increasing age. Objectives: To definite prevalence of arrhythmias in elderly inpatients treated at the Department of Cardiology of Thong Nhat Hospital - Ho Chi Minh City from January 2016 to December 2016 and the relationship between arrhythmias and some associated diseases. Methods: Retrospective study incorporating a descriptive cross-sectional study, performing a full read-back of the routine ECG on 1024 patients treated at the Department of Cardiology of Thong Nhat Hospital. Results: The rate of arrhythmias in the age 60 years and more is 51%. Arrhythmias include atrial arrhythmias (30.6%), conduction disorders (22.3%) and ventricular arrhythmias (6.6%). Atrial fibrillation accounts for 10.7%. Conclusions: Arrhythmias are frequent in the elderly and equal between men and wonmen. Atrial fibrillation is the most common arrhythmia in the elderly and gradually increases in men after age of 60. There is no difference in the prevalence of arrhythmias among the elderly and younger people.
Development and validation of a HPLC method for simultaneous quantitative determination of adapalene and benzoyl peroxide in gel products
Authors:   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam, Nguyen Van-Ha , Pham Toan-Quyen ,   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam, Nguyen Thi-Bao-Anh ,   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam, Bui Thi-Phuong ,   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam, Thai Thuy-Trinh ,   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam, Pham Nhu-Quynh ,   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam, Ly Le-Duy ,   School of Medicine, Vietnam NationalUniversity, Ho Chi Minh City, Vietnam, Le Minh-Tri ,   School of Medicine, Vietnam National University, Ho Chi Minh City, Vietnam
Published: September 2023

Adapalene (AP) and Benzoyl peroxide (BO) have been used to treat acnes very efficient for many years, especially in gel products. But nowaday, that gel products still don't have in-house standard. And furthermore, the most difficult thing to build in-house standard is to assay simultaneously. The aim of this research is to build a method to assay two of AP and BO simultaneously by HPLC method. Subjects: AP (from India) and BO (from China). Solvents get the quality standard to use in liquid chromatography. Sample: gel product (AP 0.1% and BO 2.5%) prepared at Laboratory of School of Medicine, National University of HCMC. Chromatographic system: HPLC Shimadzu system with column C18 RP (250 x 4.6 mm; 5 mm), injection volumn 20 mL, detector at 270 nm, flow rate 1 mL/min, temperature 30oC, mobile phase with acetonitril - tetrahydrofuran - acid formic 0.1% in water 42 : 32 : 26. Validations: system suitability, specificity, linearity, accuracy, precision adapt to ICH. Results: The HPLC method for simultaneous quantitative determination of adapalene and benzoyl peroxide in gel products was built successfully. The method was achieved all validations term adapt to ICH: system suitability, specificity, linearity, accuracy, precision. Furthermore, that method is used to assay the concentration of two API (AP and BO) in the product (prepared at Laboratory of School of Medicine, National University of HCMC) with result: the concentration of AP is 101.38 0.87% and that of BO is 95.56 0.04 %, get the standard of USP 41.
Role of fluid biomarkers in the early diagnosis of Alzheimer’s disease
Authors:   Department of Biomedical Engineering, School of Medicine, Vietnam National University Ho Chi Minh City (VNU-HCM), Ho Chi Minh City 70000, Vietnam, Vo Giau Van , Nguyen Minh Nam ,   School of Medicine, Vietnam National University HCM city, Vo Toi Van ,   School of Biomedical Engineering, International University, Vietnam National University Ho Chi Minh City (VNU-HCM), Ho Chi Minh City 700000, Vietnam
Published: September 2023

Alzheimer’s disease (AD) is the most common form of dementia in the elderly, which is clinically characterized by the progressive deterioration of memory and other cognitive functions that results in the loss of autonomy and ultimately leading to death. Increasing life expectancy has resulted in AD becomes a global public health concern, especially in developing countries as Vietnam. While there is currently no effective treatment for the disease, early detection of AD is critical to slow disease progression, prevent long-term morbidity and mortality, as well as reducing healthcare spending. The diagnosis of AD currently relies on clinical criteria, including mental status assessment, neurological examination, and brain imaging tests. However, these imaging methods are conclusive only in the advanced stages of disease, whereas AD physiopathology begins several decades before onset of the first symptoms. It is therefore particularly important to identify potential biomarkers that can be used in the early detection of AD aim to evaluate the efficiency of therapeutic agents under testing and to thus accelerate the therapeutic discovery process. The aim of the review was to highlight the current knowledge as well as future perspectives on the role of biomarkers in screening, diagnosis, treatment and follow-up of Alzheimer’s disease.
Investigating the Effects of Four Weeks of Spinal Nerve Ligation After a Period of Combined Training on the Expression of Involved Genes in Calcium Current in Plantaris Muscle of Male Wistar Rats
Authors:   Department of Sports Sciences, Faculty of Literature and Humanities, Vali-e-Asr University, Rafsanjan, Iran., Kazemi Abdolreza , Kerendi Hadi ,   Department of Physical Education and Sports Sciences, Faculty of Literature and Humanities, Lorestan University, Khorramabad, Iran., Naghizadeh Sobhan ,   Department of Sports Sciences, Faculty of Literature and Humanities, Kerman Branch, Islamic Azad University, Kerman, Iran.
Published: September 2023

Aims This study aims to investigate the effect of spinal nerve ligation (SNL) after a period of combined training on the expression of some genes that are involved in the calcium flow in the plantaris muscle of male Wistar rats. Methods & Materials A total of 16 adult male Wistar rats were randomly divided into 2 groups, namely the control-SNL (n=8) and combined training-SNL (n=8). The animals in the training group participated in a training program for 6 weeks. After this period, the protocol of spinal SNL was performed on the research groups for 4 weeks. Finally, the rats were dissected and the plantaris muscle was removed. Real-time polymerase chain reaction was used to measure the mRNA expression of STIM1, ORAI1, and MG29 genes. Findings In the combined training-SNL group, an increase in the expression of STIM1 (P=0.01), ORAI1 (P=0.002), and MG29 (P=0.02) was observed when compared to the control-SNL group. Conclusion The results of the present study showed that SNL reduces the expression of STIM1, ORAI1, and MG29 in the plantaris muscle. Meanwhile, combined training before SNL has a compensatory effect in this regard.
Investigating the Frequency of Delta 32 (∆32) Mutation Related to CCR5 Chemokine Receptor in Patients at Gonabad Health Centers, Iran
Authors:   Infectious Diseases Research Center, Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran., Tehranian Faeze , Nezami Hossein ,   Department of Epidemiology and Biostatics, Student Research Committee, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran., Jafarzadeh Maivan Mohammad Hossein ,   Infectious Diseases Research Center, Student Research Committee, Gonabad University of Medical Sciences, Gonabad, Iran., Akbarzadeh Sani Javad ,   Allameh Bahloul Gonabadi Hospital, Gonabad University of Medical Sciences, Gonabad, Iran., Hajavi Jafar ,   Department of Microbiology, Infectious Diseases Research Center, Faculty of Medicine, Gonabad University of Medical Science, Gonabad, Iran.
Published: September 2023

Aims Chemokine receptor type 5 is recognized as the main co-receptor in HIV infection. Many studies have shown that the deletion of 32-base pairs (bp) of both alleles of CCR5 leads to the reduction or elimination of the expression of this gene in immune cells and the natural resistance to HIV infection. This study aims to determine the frequency of delta 32 mutations in healthy people, referring to the health center of Gonabad City, Iran, to focus on finding new treatment methods for the treatment of HIV. Methods & Materials In this descriptive cross-sectional study, after obtaining ethical approval and informed consent, blood samples were collected from 293 healthy people along with ethylenediaminetetraacetic acid anticoagulant. Genomic DNA extraction was carried out by the kit, and the investigation of delta 32 (∆32) mutation of the CCR5 gene was investigated via the polymerase chain reaction method. Findings Our results showed that out of 293 people who referred to the health center, 269 people (91.8%) had a healthy gene without mutation (188 bp), 15 people (5.1%) had heterozygous mutations (188 bp and 156 bp), and 9 people (3.07%) had a homozygous mutation on both alleles of CCR5 (156 bp). Conclusion Based on the results, the homozygous mutation rate of Gonabad Region, Iran, in the studied community is higher compared to similar studies, and more epidemiological and molecular studies are needed for better conclusions.
Acetylcholinesterase Inhibitory Activity of Standardized Cannabinoids-rich Fractions
Authors:   Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Thailand., Suttithumsatid Wiwit , Kara Jiraporn ,   Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Thailand., Lomlim Luelak ,   Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Thailand., Nualsri Charassri ,   Agricultural Innovation and Management Division, Faculty of Natural Resources, Prince of Songkla University, Hat-Yai, Thailand.
Published: September 2023

Background: Since cannabis has been legally allowed for medicinal purposes in many countries, it has become the most interesting issue, particularly in neurologic disorders, such as Alzheimer’s disease (AD). Inhibition of acetylcholinesterase (AChE) is one of the mechanisms for the treatment of AD. Objectives: The present study aimed to establish a method for the preparation of cannabinoid-rich extracts and determine their AChE inhibitory activity. Methods: The cannabinoid-rich extracts were prepared through a green extraction process using microwave-assisted extraction (MAE) followed by hydrophobic column separation. The contents of cannabidiol (CBD) and Δ-9-tetrahydrocannabinol (THC) were determined using high-performance liquid chromatography (HPLC). In vitro AChE inhibitory activity was determined via the photometric method using AChE from Electrophorus electricus. Results: Three cannabinoids-rich fractions were obtained with different concentrations of CBD and THC, namely Fractions I (CBD of 8.1% w/w; THC of 52.2% w/w), II (CBD of 9.2% w/w; THC of 8.0% w/w), and III (CBD 1.3% w/w, THC 33.5% w/w). These cannabinoid-rich extracts exhibited AChE inhibitory activity, with IC50 values of 52.3, 59.8, and 71.2 µg/mL, respectively. Conclusion: This finding suggests that CBD, but not THC, might be an active compound contributing to AChE inhibitory effect.
Representation of urban subalterns in Ettela’at newspa - per(1926-1953): inefficient state and powerless subjects in struggle for survival
Authors:   Ph.D. in Sociology, Department of Sociology, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran., Zakeri Alireza , Fouladiyan Majid ,   Ph.D. in Sociology, Department of Social Sciences, Faculty of Literature and Humanities, Ferdowsi University of Mashhad, Mashhad, Iran., Moghaddam Melika ,   M.A student in sociology, Department of Sociology, Faculty of Social Sciences, University of Tehran, Tehran, Iran.
Published: September 2023

Introduction: The representation of subalterns in written texts is one of the formative factors contributing to the social life. Furthermore, by considering the representations of subalterns in written texts, one can gain insights into the mindset of the authors regarding subalterns and how they approach these groups. Method: Our objective in this paper is first to examine various issues of the "Ettela'at" daily throughout years to uncover the representation of subalterns in a government newspaper and to reconstruct perspective of the national bureaucracy towards them. Second, we aim to depict some of the modes of interaction of subalterns with the government during these years, as far as they have been portrayed in the government newspaper "Ettela'at". Our focus will be on the representation of subalterns in Tehran. Findings: subalterns become visible only during times of crisis and critical situations. They are often collected and returned to their places of origin and sometimes are assigned a temporary job, always subject to inspection. Regarding the government's approach to subalterns, we can talk of the "dialectic of inefficiency". Discussion: In terms of the interaction between urban subalterns and the government, in the absence of basic life necessities such as work and bread, their focus is primarily on survival. They cannot think, let alone reach, beyond the confines of this immediate struggle.
Analisis Faktor-Faktor yang Mempengaruhi Keputusan Konsumen Memilih Warung Kopi Arabika di Kota Meulaboh
Authors: Irawan Risnadi , Kamal Mustafa , Ayunda Hanif Muchdatul , Adib Adib , Akmal Abdiel Khaleil , Marlinda Marlinda , Pandria T. M. Azis
Published: September 2023

Seiring dengan peningkatan pertumbuhan ekonomi pasca bencana gempa dan tsunami aceh tahun 2004 mempengaruhi tingkat pertumbuhan warung kopi di kota Meulaboh. Hal ini juga menjadi pendorong meningkatnya jumlah konsumen dan berbagai karakter serta sejumlah latar belakang konsumen penikmat kopi. Penelitian ini bertujuan untuk mengelompokan konsumen ke dalam beberapa kategori yang didasari faktor-faktor yang mempengaruhi keputusan konsumen dalam memilih warung kopi arabika. Penggunaan teknik analisis multivariate dari Principle Component Analysis (PCA) dalam analisis data penelitian dengan tahapan seperti perhitungan matriks korelasi, analisis faktor dan mengestimasi muatan setiap faktor dengan metode estimasi maksimum. Hasil penelitian menunjukan persentase kelima kelompok konsumen warung kopi arabika di Kota Meulaboh ialah penikmat kopi 17,1%, konsumen umum/konvensional 14,2%, konsumen sosialita 13,4%, konsumen trendi 12,8%, konsumen gaya hidup 12,2%. Dapat disimpulkan bahwa banyak konsumen memilih warung kopi arabika dikarenakan cita rasa dan kualitas dari kopi yang disajikan, kelompok ini termasuk kedalam orang yang mengerti kopi. Selain kelompok penikmat kopi, warung kopi arabika di Kota Meulaboh juga dikunjungi dari 4 kelompok lainnya seperti konsumen umum yang memilih warung kopi arabika dikarenakan rekan kerja, konsumen sosialita karena hubungan sosial, konsumen trendi karena gengsi dan konsumen gaya hidup dengan alasan brand dan status sosial.
A Short Communication: Contamination and Toxicity Pigment Red 53, Rhodamine B, and Sudan III in Indonesian Cosmetics
Authors: Fikri Elanda , Firmansyah Yura Witsqa
Published: September 2023

The high sales of cosmetic products in the world are not directly proportional to the good quality of cosmetic products. The The Food and Drug Administration (BPOM) declared, from October 2021 to August 2022 as many as 1 million pieces of cosmetic products contain Pigment Red 53, Rhodamine B, and Sudan III which are hazardous and prohibited ingredients. This study aims to disseminate information on case reports and toxicity of Pigment Red 53, Rhodamine B, and Sudan III contamination in Indonesian cosmetics. The study used a descriptive method with a case report study design. The study used secondary data, namely a list of cosmetic products containing Pigment Red 53, Rhodamine B, and Sudan III obtained from the website of the Indonesian authorities through the BPOM. Data collection was carried out on 4-5 October 2022. The BPOM declared 16 cosmetic products from 5 incorporated containing Pigment Red 53, Rhodamine B, and Sudan III. Undoubtedly, BPOM reported cases of Pigment Red 53, Rhodamin B, and Sudan III contamination still occurring from October 2021 to August 2022. The existence of these dyes should not be used as a mixture of cosmetics and personal care. In line with dangerous toxicity, these dyes are mutagenic, genotoxic, and carcinogenic. The BPOM must work even harder in its efforts to monitor safe cosmetic products to protect the health of the Indonesian people.
Pengaruh Variasi Temperatur Tempering Terhadap Nilai Kekuatan Tarik dan Kekerasan Baja Karbon Sedang
Authors: Yusuf Ilyas , Nurlaili Nurlaili
Published: September 2023

Penelitian ini bertujuan untuk mengetahui pengaruh variasi temperatur tempering baja karbon sedang terhadap kekuatan tarik dan nilai kekerasan. Baja karbon sedang yang telah dibentuk menjadi spesimen uji dilakukan proses perlakukan panas hingga temperatur 8300C, holding time 60 menit dan di-quenching pada media oli. Spesimen yang telah pada temperatur normalÂ  kemudian dilakukan proses tempering dengan temperatur 3000C, 4500C dan 5500C dan holding time selama 40 menit. Spesimen dilakukan karakterisasi uji tarik dan kekerasan menggunakan metode Rockwell. Material dasar yang diuji komposisi kimia menunjukkan material memiliki kandungan karbon 0,47%. Hasil pengujian didapat spesimen B1 dengan temperatur tempering 4500C memiliki nilai rata-rata kekuatan tarik tertinggi sebesar 125.36 kg/mm2 dan terendah pada sampel C1 dengan temperatur tempering 5500C dengan kekuatan tarik Â 84.31 kg/mm2. Sedangkan dari hasil pengujian kekerasan dihasilkan oleh sampel A1 dengan temperatur tempering 3000C dengan kekerasan 76.9 HRC dan terendah sampel C1, temperatur tempering 5500C, dengan kekerasan 71.1 HRC. Baja karbon sedang yang mengalami proses tempering mengalami penurunan kekuatan tarik dan kekerasan seiring dengan meningkatnya temperatur tempering.
Perencanaan Reservoir Air Bersih di Wilayah Pelayanan IPA Legong PDAM Tirta Asasta Depok
Authors: Azizi Aqil , Emira Delita
Published: September 2023

Meningkatnya jumlah penduduk di kota Depok setiap tahun berdampak kepada meningkatnya kebutuhan akan air bersih. Sebagai perusahaan air minum daerah, PDAM Tirta Asa perlu merencanakan kebutuhan air bersih dan menghitung kapasitas reservoir untuk memenuhi kebutuhan air pelanggan. Tujuan dari penelitian ini adalah untuk menentukan volume efektif reservoir di IPAL Legong sebagai salah satu IPAL dengan kapasitas pengolahan terbesar, memproyeksikan kebutuhan air bersih, dan menghitung volume efektif reservoir untuk periode 20 tahun ke depan. Metode tabulasi digunakan untuk menghitung kondisi eksisting, sedangkan rumus proyeksi digunakan untuk memproyeksikan kebutuhan 20 tahun mendatang. Rumus proyeksi yang digunakan adalah aritmetika, geometri, eksponensial, regresi linear, logaritmik, dan least square yang kemudian akan dipilih yang terbaik untuk perhitungan proyeksi. Metode least square terpilih untuk menghitung proyeksi kebutuhan air domestik, sedangkan logaritmik terpilih untuk kebutuhan air non domestik. Volume efektif reservoir IPA Legong berdasarkan perhitungan metode tabulasi berkapasitas 4.700 m3. IPA Legong saat ini berkapasitas 6700 m3, sehingga kapasitas reservoir masih mampu menampung kebutuhan air pelanggan. Hasil proyeksi untuk 20 tahun ke depan, permintaan air bersih pelanggan adalah 704,64 liter/detik, dan rata-rata kebutuhan air hariannya adalah 826,55 liter/detik. Volume reservoir yang diperlukan adalah 12.854,45 m3, sehingga PDAM perlu menambah kapasitas reservoir sebesar 6200 m3.
Penerapan Metode Overall Equipment Effectiveness Dalam Pengukuran Efektivitas Mesin Press Kennedy Ken-503-9470k di PT. ABC
Authors: Dhuha Syamsi , Wahyudin Wahyudin , Pamungkas Sitorus Sutrisna Sunjaya Stepanus
Published: September 2023

Ketidakmampuan dalam menangani dan merawat mesin dengan baik dapat mengakibatkan penurunan tingkat kinerja dan efektivitasnya, yang berdampak pada kualitas produk yang dihasilkan. PT ABC adalah sebuah perusahaan yang berfokus pada pengadaan suku cadang kendaraan. Objek penelitian adalah mesin Kennedy Ken-503-9040k yang mengalami kendala dalam hal waktu henti yang terlalu lama, sehingga menghambat proses produksi. Tujuan penelitian ini adalah untuk melakukan analisis terhadap efektivitas mesin Kennedy Ken-503-9040k dan menghitung kerugian akibat rendahnya efektivitas mesin tersebut, dengan mengevaluasi hasil analisis Overall Equipment Effectiveness (OEE) yang digunakan sebagai indikator standar mesin Kennedy Ken-503-9040k. Hasil penelitian OEE untuk periode Januari hingga Desember 2022 menunjukkan nilai sebesar 64,59%, sehingga masih di bawah standar global JIPM yang mencapai 85%. Secara keseluruhan, dapat disimpulkan bahwa mesin belum mencapai kriteria World Class. Faktor-faktor yang berkontribusi terhadap rendahnya nilai OEE pada mesin Kennedy Ken-503-9040k meliputi rendahnya kualitas suplai bahan (material), mesin yang sering mengalami gangguan (mesin), keterbatasan tenaga kerja (manusia), ketidakteraturan jadwal maintenance (metode), dan kondisi lingkungan kerja yang tidak nyaman (lingkungan).
Analysis of the Effect of in-Late Angle and Lower Valve Position in the Semi Jet Type Water Pump Installation Against Water Debit
Authors: Kustanto Heri , Wiyono Wiyono , Widodo Lujeng , Adji M. Azzis Purnomo , Yohanes Antoni
Published: September 2023

The problem that often occurs in people who use semi-jet water pumps is that when the installation of the water pump has been completed, it turns out that the water discharge cannot flow as expected and the electricity consumption is quite large. This research is expected to get optimal results, when installing the water pump installation, it is expected to get the largest water discharge by varying the valve location with the in-late angle, so that it will reduce the time to use the water pump. The experimental results with the linear regression method show that optimal conditions are achieved at variation 8 meaning to maximize the water discharge at the semi-jet water pump, namely the location of the valve above with an in-late angle of 450. The results of the comparison between the average value of water discharge for general use conditions are 29 .6 liters/minute with an average value of water discharge under optimal conditions of 34.8 liters/minute, indicating that the value of water discharge under optimal conditions can increase the water discharge by 5.2 liters/minute = (34.8 liters/minute â€“ 29 ,6 liter/minute), so there is an increase of 8.0745 % = { [5,2 / (34,8+29,6)] x 100%}.
Penggunaan Metode Balanced Scorecard untuk Analisis Kinerja Perusahaan
Authors: Purnamasari Indah , Fitriani Risma
Published: September 2023

Seiring dengan adanya perubahan secara terus menerus yang diikuti dengan kompetitifnya dunia bisnis mengharuskan suatu manajemen perusahaan untuk dapat menetapkan strategi yang tepat. Dalam penetapan strategi dibutuhkan penilaian kinerja perusahaan secara komprehensif, maka penelitian ini bertujuan untuk mengetahui kinerja perusahaan yang ditinjau dari empat perspektif yaitu perspektif keuangan, perspektif pelanggan, perspektif proses internal bisnis, serta perspektif pertumbuhan dan pembelajaran. Metode yang digunakan dalam penelitian yaitu metode kualitatif dengan teknik analisis deskriptif karena penelitian ini bertujuan untuk mengungkapkan keadaan pada saat penelitian dilakukan dan tidak untuk membuktikan suatu hipotesis. Dari hasil yang didapatkan bahwa PT. Telkom berdasarkan penilaian kinerja menggunakan metode balanced scorecard berada pada kategori A yang menandakan kinerja perusahaan sangat baik, namun pada perspektif keuangan memiliki nilai yang rendah dibandingkan dengan tiga perspektif lainnya. Dengan demikian perlu dilakukan strategi yang dapat meningkatkan kualitas aspek keuangan perusahaan serta melakukan upaya-upaya untuk perbaikan perusahaan baik secara internal maupun eksternal.