bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-medication for anxiety symptoms in the context of COVID-19, in users who go to a drugstore in Los Olivos, Lima in 2021
Authors: Esteves Pairazaman Ambrocio Teodoro , Ñañez del Pino Daniel , Ibarra Fretell Walter Gregorio , Arbieto Mamani Oscar , Pozo Enciso Rosmery Sabina , Esteves Cardenas Veronica Liset , VALVERDE FLORES YSABEL , ARIAS ANCHIHUAY ELISABET FIORELA , MANRIQUE CARHUAS PABLO RAFAEL
Published: September 2022

Background: Self-medication is a non-responsible act and leads to the inappropriate use of medications, causing low effectiveness and insecurity in treatments. The aim of this study is to determine the relationship between self-medication and anxiety symptoms in the context of coronavirus disease 2019 (COVID-19), in users attending a pharmacy in Los Olivos, Lima in 2021.

Methods: The research method was deductive, basic and with a quantitative approach; the design used was non-experimental, descriptive, correlational, cross-sectional, and prospective. Spearman's Rho analysis was performed to validate the hypothesis.

Results: 384 users were evaluated, finding 93.5% aged 18-59 years, of whom 53.4% were female, 42.7% had completed high school, 57.8% were single and 51.6% presented physical symptoms, predominantly muscular tension accompanied by pain, 60.7% presented behavioral symptoms, highlighting unusual sadness in the face of COVID-19 and 70.1% presented cognitive symptoms with greater frequency of concern about contracting COVID-19. In addition, the greater the symptoms of anxiety, the higher the self-medication increased from 9.0% to 21.1%. A similar case was evidenced in self-medication on their own initiative where the increase was from 7.5% to 33.3%; likewise, self-medication without medical prescription increased from 15.8% to 47.7%, and the consumption of anxiolytics or antidepressants increased from 0.8% to 26.3% caused by the symptoms of anxiety.

Conclusion: It was determined that there is a moderate relationship between self-medication and anxiety symptoms in the context of COVID-19, in users who go to a drugstore in Los Olivos, Lima in 2021.
Highlights of the 1st Ecuadorian-Venezuelan Symposium of Young Researchers in Bioinformatics (1SEVJIB)
Authors: Ayala-Ruano Sebastian , Hernandez Fernando , Ortega Arantxa , Infante Deliana , Carrascal Daniela , Sánchez-Luquez Karen , Puche-Quiñonez Rafael
Published: September 2022

The COVID-19 pandemic profoundly changed how scientific conferences are

organized, fostering virtual meetings. These online events have allowed students

and researchers to overcome geographical, administrative and economic barriers to

attend and organize high-quality international symposiums. Moreover, these virtual

conferences have contributed to the creation of inclusive activities that strengthen

scientific communities. Here, we summarize the main activities and learnings from

the 1st Ecuadorian-Venezuelan Symposium of Young Bioinformatics Researchers

(1SEVJIB), organized by the Ecuadorian and Venezuelan ISCB-SC Regional

Student Groups (RSGs). This symposium aimed to provide an opportunity for

undergraduate and postgraduate students from Ecuador, Venezuela, and other Latin

American countries to share their Bioinformatics research. The 1SEVJIB was the first

bi-national conference organized by two RSGs from Latin America (LatAm). This

symposium was a two-day virtual meeting with five activities: 1) oral student

presentations, 2) poster session, 3) keynote lectures, 4) workshop, and 5) round

table. This conference promoted the scientific exchange and cooperation networks

between young Bioinformatics researchers and students from Ecuador, Venezuela,

and LatAm, giving them opportunities to boost their scientific careers.
Mobilefuge: A low-cost, portable, open source, 3D-printed centrifuge that can be powered by a mobile phone
Authors: Bhupathi Mohini , Devarapu Ganga Chinna Rao
Published: September 2022

Background: A centrifuge is an essential piece of equipment for several biology and diagnostic applications such as pelleting cells and purifying nucleic acids, etc. In recent years, there has been an increasing interest for low-cost centrifuges that are alternatives to the commercially available centrifuges. In this article, we present a low-cost, open-source, 3D printed centrifuge (mobilefuge) that is portable, robust, stable, safe, easy to build and operate.

Methods: The mobilefuge was designed such that it doesn't require soldering or programming skills and can be built without any specialised equipment yet practical enough for high throughput use. More importantly, the mobilefuge can be powered from widely available 5V USB ports, including mobile phones and associated power supplies. This allows the mobilefuge to be used even in off-grid and resource limited settings.

Results: Performance of the mobilefuge is demonstrated by separating silica particles are from a suspension consisting of water and “glassmilk”. This separation process is one of the crucial steps in nucleic-acid amplification assays for reliable, low-cost diagnostic applications such as SARS-CoV2.

Conclusions: We believe that beyond the nucleic-acid assays, the mobilefuge can have several applications as a microcentrifuge in the field of biomedical research and diagnostics.
Integrated Backup Rolling Stock Allocation and Timetable Rescheduling with Uncertain Time-Variant Passenger Demand Under Disruptive Events
Authors: Yin Jiateng , Yang Lixing , D’Ariano Andrea , Tang Tao , Gao Ziyou
Published: September 2022

Railway traffic management focuses on regulating train movements and delivering improved service quality to passengers; however, such efforts are subject to many uncertainties in terms of disruptions and passenger demand on a rail transit line. In contrast to most existing studies, which focus on the rescheduling of passenger timetables in a deterministic framework, this study proposes a two-stage stochastic optimization model for allocating backup rolling stocks (BRS) to storage lines to reschedule the timetable and serve passengers delayed by disruptions. The first stage is an assignment problem to determine the optimal plan for the allocation of BRS to storage lines to achieve a good trade-off between the investment cost for the BRS and the expected travel time of delayed passengers across different stochastic scenarios. The second stage is explicitly formulated as a network flow model to optimize the timetable of the delayed trains on the tracks and the BRS from the storage lines such that the passenger travel time is minimized under each stochastic scenario. To improve the efficiency of convergence, we develop an improved L-shaped method with several accelerating techniques. Among these, we show that the classical integer L-shaped cut can be tightened given the property of the second-stage problem, which can also be generalized to other two-stage integer stochastic programs. Real-world case studies based on historical data from the Beijing metro verify the effectiveness of the proposed approach in reducing the travel time for passengers.

History: Accepted by Pascal Van Hentenryck, Area Editor for Computational Modeling: Methods & Analysis.

Funding: This research was supported by the National Natural Science Foundation of China [Grants 71621001, 71825004, and 71901016].

Supplemental Material: The software that supports the findings of this study is available within the paper and its Supplementary Information [ https://pubsonline.informs.org/doi/suppl/10.1287/ijoc.2022.1233 ] or is available from the IJOC GitHub software repository ( https://github.com/INFORMSJoC ) at [ http://dx.doi.org/10.5281/zenodo.6892548 ].
3D Events with Stereoscopy with a single Dynamic Vision System
Authors: Ilani Raviv , Reich Adi , Schindelhaim Moshik , Stern Adrian
Published: September 2022

Considering the cost of a single event-based camera, classical 3D imaging approaches using two or more synchronized cameras may be cost-prohibitive. This work explores 3D imaging using a single stationary camera and a stereoscopic lens setup.
A 100 volume/s light-sheet microscope applied to 3D motion measurement of freely swimming cells
Authors: Arai Kazuki , Oku Hiromasa
Published: September 2022

We report a high-speed light-sheet microscope composed of TAG lens and galvanometer mirror, which was applied to 3D motion measurement of Chlamydomonas at 111 Hz.
A Varifocal Camera System for Light Field Display Calibration
Authors: Lu Yanzhao , Wang Xuan , Hua Hong
Published: September 2022

This paper presents the design and characterization of a varifocal camera system that is specially developed for head-mounted light field display calibration.
High-Resolution Integral Imaging 3D Display System Based on Compound Lens Array
Authors: Wang Tong-Yu , Li Wei-Ze , Zhang Han-Le , Wang Qiong-Hua , Xing Yan
Published: September 2022

We propose a high-resolution integral imaging 3D display system based on compound lens array. The experimental results demonstrate that high-resolution 3D images can be reconstructed within the viewing area.
Single-pixel fluorescence microscopy with optical sectioning
Authors: Ordóñez Luis , Ipus Erick , Lenz Armin J. M. , Lancis Jesús , Tajahuerce Enrique
Published: September 2022

We present a single-pixel microscope with optical sectioning by combining two structured illumination methods: structured illumination microscopy (SIM) and single-pixel imaging (SPI). Experimental results are shown for the application in 3D fluorescence microscopy by scanning different axial planes.
Common-path Incoherent Digital Holography Using Polarizing Optical Elements
Authors: Nishimura Masaya , Quan Xiangyu , Matoba Osamu
Published: September 2022

A novel off-axis incoherent digital holographic microscopy using polarization gratings and a geometric phase lens is proposed. The polarization gratings and geometric phase lens works to the left and right handed circular polarized light differently. The preliminary experiment result using a micro-fluorescence bead is presented.
The Lightfield Eyepiece: an Add-on for 3D Microscopy
Authors: Incardona Nicolo , Tolosa Angel , Scrofani Gabriele , Martinez-Corral Manuel , Saavedra Genaro
Published: September 2022

Fourier lightfield microscopy is an emerging technique for real-time acquisition of three-dimensional microscopic samples. Here, we present the lightfield eyepiece, an add-on device capable of converting any conventional microscope to a Fourier lightfield microscope.
Monte-Carlo based analysis of polarimetric calibration of liquid crystal devices
Authors: Márquez Andrés , Sánchez-Montes Adriana R. , Francés Jorge , Puerto Daniel , Calzado Eva , Gallego Sergi , Pascual Inmaculada , Beléndez Augusto
Published: September 2022

An advanced polarimetric model for liquid crystal devices is presented and the sources of uncertainty to determine the values of its parameters are evaluated using a Monte-Carlo approach.
Multi-view Sensing for Snapshot Pattern Recognition, Polarimetric and Phase Quantitative Microscopy
Authors: Fernández Ariel
Published: September 2022

By exploiting the redundancy derived from multi-view sensing of a sample, image capture with different pupil masks under a lenslet array allows for snapshot pattern recognition, Stokes parameters retrieval as well as phase quantitative microscopy.
Generation of Double Focal Spots by Focusing Azimuthally Polarized Double Ring Shaped Beam with Annular Classical Axicon
Authors: Alkelly Abdu A. , Loqman Ibrahim G. H. , Al-Ahsab Hassan T.
Published: September 2022

Double focal spots have been generated in the focal region of annular axicon by focusing azimuthally polarized double-ring-shaped (APDRS) beam. Our results indicate that the properties of twin spots are affected by axicon and beam parameters.
Upgrading Interferometric Focal Length Measurement Techniques with Adaptive Optics
Authors: Imeri Arjent , Reza Syed Azer
Published: September 2022

In this paper, we attempt to automate, compactify, and forego bulk optical motion in existing ruling-based, double frequency-based, and Twyman-Green interferometer-based interferometric focal length measurement techniques via an addition of an adaptive optics element.
Multi-Species Sensing Using CEAS and DNN in Shock Tube Kinetics
Authors: Mhanna Mhanna , Sy Mohamed , Elkhazraji Ali , Farooq Aamir
Published: September 2022

Simultaneous multi-species sensing in shock tube experiments are performed using a single laser source. A tunable DFB-ICL emitting near 3.3 µm, off-axis CEAS, and DNN enabled sensitive and selective measurements of target species.
Nanotemplates for humidity sensing layers made by two-photon-polymersation printing
Authors: Cesnik Stefan , Rodríguez Gabriel Hernández , Coclite Anna Maria , Bergmann Alexander
Published: September 2022

Nanotemplates were directly fabricated with a two-photon-polymerisation 3D printer. Afterwards, the templates were coated with a humidity responsive hydrogel using initiated chemical vapor deposition. Finally, the humidity response of the nanostructures was successfully measured.
Magnetic modulation of IR properties of rod-slit complementary spintronic metasurfaces in presence of a molecular vibration
Authors: Bergamini Luca , Armelles Gaspar , Cebollada Alfonso , Gonzales M. Ujue , Alvaro Raquel , Torne Lorena , Zabala Nerea , Aizpurua Javier
Published: September 2022

We show that the magnetic-modulation of the optical response induced by an external magnetic field in giant-magneto-resistance rod-slit arrays is more sensitive to the presence of a molecular vibration than the direct optical response.
Low-Coherence Diode Laser Array Light Source for High-Speed Imaging
Authors: Crabtree Christopher Q. , Albertson Robert J. , Noftz Mark E. , Slipchenko Mikhail N. , Jewell Joseph S. , Meyer Terrence R.
Published: September 2022

High-Speed shadowgraph imaging requires pulsed, intense, and low coherence light radiation to achieve high signal-to-noise ratio. This summary details the development of a laser diode array light source, and its use for shock wave visualization.
Mirror Overlay Imaging System for High Magnification with Large FOV
Authors: Sugahara Shun , Hayashi Yusuke , Fujiyoshi Hironobu
Published: September 2022

A novel optical system for high magnification with large FOV is proposed that overlays images using mirrors arranged to the sides of the image sensor, and that reconstructs a large FOV image by using DNN.
Stress Fields Extraction in Multi-Polarized Photoelasticity Images Using Deep Convolutional Neural Networks
Authors: Naranjo Diego Eusse , Briñez-De León Juan C. , Restrepo-Martínez Alejandro
Published: September 2022

Digital photoelasticity requires demodulating stress fields, wrapped into color fringe patterns. As an alternative to traditional methods, deep convolutional neural networks are trained to recover stress maps from isochromatic images related to different orientations of a polarized camera, reaching high precision in different analytical models.
3-D Localization of Micromanipulators Using Microscopy for Autonomous Visual Servoing
Authors: Mei Ryan , Panitch William , Waller Laura
Published: September 2022

We rapidly determine the 3-D position of a glass-pipette micromanipulator using color-coded illumination and optical microscopy, and demonstrate its potential for autonomous visual servoing and multi-manipulator systems for highly parallelized cell manipulation.
Digital stitching holographic microscopy for precise tribology measurement
Authors: Mach Marek , Stašík Marek , Kaván František
Published: September 2022

Digital stitching holographic microscopy is a promising method for extensive surface area inspection. It offers high lateral and axial resolution and large area imaging, making it suitable for evaluating tribologic tests.
Motion Picture Recording of Propagation of a Light Pulse by Digital Light-in-flight Recording by Holography Using a Biological Specimen as a Diffuser
Authors: Tsuji Asuka , Inoue Tomoyoshi , Nishio Kenzo , Kubota Toshihiro , Matoba Osamu , Awatsuji Yasuhiro
Published: September 2022

We propose digital light-in-flight recording by holography that uses a biological specimen as a diffuser. By the proposed method, we successfully recorded a motion picture of light pulse propagating through a slice of pork.
Using a Modulated Quantum Cascade Laser for Photoacoustic Spectra Recording of Exhaled Acetone and Main Breath Components
Authors: Pangerl Jonas , Wittmann Elisabeth , Weigl Stefan , Müller Max , Bierl Rudolf , Matysik Frank-Michael
Published: September 2022

Photoacoustic spectra of main breath components together with acetone are presented demonstrating spectral linearity towards different concentrations and compositions. The acetone 3σ detection limit at 1209 cm
−
1 is 0.28 ppbV.
Near-infrared polarization-based optical system for delineating healthy and fibrotic heart tissues
Authors: Twinkle  , Kamal Arif Mohd. , Pandya Hardik J.
Published: September 2022

A near-infrared (NIR) linear polarization-based optical system is designed and developed for distinguishing between healthy and fibrotic heart tissues by quantifying the degree of linear polarization (DOLP) of the left ventricle (LV) and right ventricle (RV) tissues.
Plasmonic Sensors for Pathogen Detection
Authors: Tay Li-Lin , Huang Ping-Ji , Chau Lai-Kwan
Published: September 2022

Plasmonic surface enhanced Raman scattering (SERS) probes were synthesized with different Raman reporter molecules and conjugated with pathogen specific antibodies to provide a rapid screening platform for the detection of pathogenic bacterium, S. aureus and S. Typhimurium.
Physics-based model of imaging of biometrics data through atmospheric turbulence
Authors: Korotkova O. , Raveh D. , Bastian K. O. , Voelz D. , Narayanswamy R. , Smith A. , King M.
Published: September 2022

Physics-based modeling and a computer simulation of the modulation transfer functions of the near-ground atmospheric channel is developed for imaging human biometrics data over a sub-kilometer range along horizontal and slant paths.
Enhanced Pyramid Wavefront Sensor via End-to-End trained diffractive optical layer
Authors: Guzmán Felipe , Bacca Jorge , Tapia Jorge , Weinberger Camilo , Arguello Henry , Vera Esteban
Published: September 2022

We propose to design an optical preconditioner using an End-to-End approach to improve the linear response of the pyramid wavefront sensor. Simulation results show a notorious improvement at different turbulence profiles.
Reconstructing Turbulent Wavefronts from Plenoptic Data Measured by a Plenoptic Wavefront Sensor
Authors: Lin Di , Watnik Abbie T.
Published: September 2022

We present a novel wavefront reconstructor adapted for measurements of turbulent wavefronts taken by a plenoptic wavefront sensor. Intensity peaks from each lenslet sub-image of the overall plenoptic image are registered and consolidated based on their respective intensities to synthesize the measured wavefront. We demonstrate our algorithm by applying it to synthetic plenoptic data generated from computer simulations of a plenoptic wavefront sensor and reconstructing a turbulent wavefront.
Modelling spherical aberration detection in an analog holographic wavefront sensor
Authors: Branigan Emma , Martin Suzanne , Sheehan Matthew , Murphy Kevin
Published: September 2022

The analog holographic wavefront sensor (AHWFS) is a simple and robust solution to wavefront sensing in turbulent environments. Here, the ability of a photopolymer-based AHWFS to detect refractively generated spherical aberration is modelled and verified.
Deep learning wavefront reconstruction for collimated beams with experimental data
Authors: González-Gutiérrez Carlos , Bharmal Nazim Ali , Muro Jorge Rodríguez , de Cos Juez Francisco Javier
Published: September 2022

A broad collimated laser beam and a pair of cameras combined with deep learning, helps to characterize atmospheric effects when observing distant objects with a telescope or the possible effects in ground communications.
Efficient and versatile sensorless aberration correction for adaptive microscopy
Authors: Hu Qi , Booth Martin J.
Published: September 2022

We proposed a machine learning assisted adaptive optics method with high photon-efficiency and versatility. The method was used on a range of microscope modalities for fast aberration correction when imaging various samples with complex structures.
Gigahertz Frame Rate Imaging via Grating Based Single-Shot Ptychography
Authors: Barolak Jonathan , Goldberger David , Ivanic Bojana , Durfee Charles , Adams Daniel
Published: September 2022

We present, for the first time to our knowledge, gigahertz frame rate, simultaneous phase and amplitude imaging on a slow detector via beam sampling single-shot ptychography. Experimental realization of the technique is demonstrated by reconstructing an SEM grid from 4 temporally separated pulse-beams.
Measurement Scheme for Convex Freeform Objects using Multiwavelength Digital Holography
Authors: Kaván František , Psota Pavel , Mach Marek , Stašík Marek
Published: September 2022

Freeform optics are quickly gaining importance in optics, but measurement methods lag behind. In this research we propose new measurement system designed especially for convex freeform objects using multiwavelength digital holography.
Non-priori coherent diffraction imaging with structured phase modulations
Authors: Li Rujia , Yang Feng , Cao Liangcai
Published: September 2022

The alternative structured phase modulation method is introduced to the coherent diffraction imaging. The phase of the object and slowly varying background can be measured robustly without a priori information.
Transmission of Photons Through an Adult Human Head
Authors: Radford Jack , Nerenberg Samuel , Faccio Daniele
Published: September 2022

We report the detection of near-IR photons diametrically transmitted through the entire adult human head from which optical coefficients are estimated. This approach could lead to applications in stroke detection and brain activity monitoring.
Adaptive single-pixel imaging through turbid media
Authors: Ipus Erick , Lenz Armin J. M. , Lancis Jesús , Paniagua-Diaz Alba M. , Artal Pablo , Tajahuerce Enrique
Published: September 2022

We present a system for imaging objects through non-homogeneous scattering media that works in an adaptive way by combining diffuse optical imaging (DOI) and single-pixel imaging (SPI) techniques. The experimental results are shown.
Easy and Flexible Calibration Approach for Deflectometry-based VR Eye-Tracking systems
Authors: Wang Jiazhang , Xu Bingjie , Cossairt Oliver , Willomitzer Florian
Published: September 2022

We present an easy and flexible calibration approach for small field of view Deflectometry systems to be used in VR headsets. Our method replaces all required calibration targets and mirrors with a small (phone) screen to perform intrinsic and extrinsic camera calibration as well as extrinsic calibration of the whole setup.
Learning a Split-and-synthesis Network for hybrid uniform and structured illumination-based phase retrieval
Authors: Wu Xiaofeng , Wu Ziling , Zhu Yunhui
Published: September 2022

Deep learning is widely used for quantitative phase imaging (QPI), but is prone to cause spatial frequency bias in the reconstruction. In this paper, we propose a split-and-synthesis framework, which consists of two-stages training and takes the phase samples based on uniform illumination and structured illumination from transport of intensity equation (TIE) as inputs. We show that our framework is efficient to calibrate the spatial frequency bias for accurate phase retrieval.
Probabilistic Regularization for End-to-End Optimization in Compressive Imaging
Authors: Jacome Roman , Hernandez-Rojas Alejandra , Arguello Henry
Published: September 2022

This paper proposes a probabilistic regularization for joint optimization of optical coding and recovery for compressive imaging. We regularize the probability distribution of the compressive measurement to improve the decoder network performance.
Experimental Demonstration of Lightsheets with Customized Properties in Simple Media
Authors: Aborahama Yousuf , Mojahedi Mo
Published: September 2022

Using ideas from the calculus of variation, we design and experimentally realize light sheets that exhibit some exotic properties, such as twisting and bending while propagating in a simple medium.
Deep Learning-Based Joint Reconstruction and System Optimization for Single-Shot Compressive Spectral Imaging
Authors: Gundogan Utku , Oktem Figen S.
Published: September 2022

We develop a joint reconstruction and system optimization method for snapshot spectral imaging with diffractive lenses. The method learns the diffractive lens design parameters jointly with a 3D deep prior in an unrolled reconstruction. Results illustrate the significance of jointly optimizing the prior and design parameters.
Unlocking Unprecedented Potential of Nanostructured Optical Elements by Advanced Nanolithography
Authors: Döring F. , Kubec A. , Sander F. , Döring C. , Erjawetz J.
Published: September 2022

Diffractive optical elements overcome the limitations of refractive lenses and provide unique functionalities in many applications from infrared to X-ray wavelengths. We present the latest highlights in the nanofabrication and application of diffractive optics.
Automated multicolour mesoscopic imaging for the 3-dimensional reconstruction of fluorescent biomarker distribution in large tissue specimens
Authors: Foo WanLing , Wiede Alexander , Bierwirth Sebastian , Heintzmann Rainer , Press Adrian T. , Hauswald Walter
Published: September 2022

We established an in-house built episcopic imaging add-on on a cryo-microtome to perform imaging during serial sectioning. This RGB and fluorescent mesoscope can provide sequential block-face and 3-dimensional anatomical images with high resolution and large field-of-view.
In-plant prototype density scanner using a real-time sub-THz imaging camera
Authors: Gehloff Maik , Reid Matthew , Hartley Ian D. , Price Brad D. , Mucchi Luca
Published: September 2022

A real-time THz sensor was installed in a MDF plant and found to measure density in the industrial plant setting at full plant operating speed with accuracy and precision comparable to lab-based X-ray measurement.
Comparison of Numerical Spectral Alignment Methods in Dual-spectrometer SD-OCT System
Authors: Miao Yusi , Song Jun , Ju Myeong Jin
Published: September 2022

To correctly implement the dual-spectrometer SD-OCT, two numerical calibration methods are demonstrated that effectively compensate for the spectral misalignment between spectrometers. Significant improvements in the image contrast are observed through retinal imaging after spectral calibration.
Modeling a Structured Light System with Open-Source Software
Authors: Quintero Fernando J. , Vargas Raúl , Romero Lenny A. , Marrugo Andrés G.
Published: September 2022

We propose modeling a structured light system with open-source computer graphics software to perform experimental verifications independently of the physical system. Encouraging experimental results show the capabilities of the digital twin.
QCL-based Cavity-Enhanced Absorption Spectroscopy of N2O at 4.5 μm
Authors: Yang Min , Wang Zhen , Nie Qinxue , Ren Wei
Published: September 2022

We present a cavity-enhanced absorption sensor for ambient N2O detection. The Pound-Drever-Hall technique was implemented to lock a quantum cascade laser to a high-finesse cavity by directly modulating the laser injection current.
Cool mid-IR Absorption Spectroscopy of cold Molecules
Authors: Nataraj Akshay , Gianella Michele , Tuzson Béla , Li Gang , Ebert Volker , Faist Jérôme , Emmenegger Lukas
Published: September 2022

We present a QCL based absorption spectroscopy setup with a Stirling cooled circular multipass absorption cell at 150 K. We report the first high-precision measurements of clumped 12C18O2 and 12C17O18O, and of site-specific propane isotopomers.
Generative Adversarial Networks for Cell Segmentation in Human Corneal Endothelium
Authors: Mendoza Kevin D. , Sierra Juan S. , Tello Alejandro , Galvis Virgilio , Romero Lenny A. , Marrugo Andrés G.
Published: September 2022

We generate synthetic images with a generative adversarial network (GAN) model trained with image patches from specular microscopy corneal endothelial cells. Preliminary results show it may be a suitable approach for reliable cell segmentation.
Parallelized 16-gigapixel microscopy for rapid imaging of multiple whole slides
Authors: Kim Kanghyun , Zhou Kevin C. , Harfouche Mark , Horstmeyer Roarke
Published: September 2022

We present a new multi-camera array microscope (MCAM) that can capture images at single micrometer resolution over 54 cm2 fields of view, which contain up to 16 gigapixels, and associated software for seamless viewing and analysis.
A Miniaturized Illumination Unit for Airy Light-Sheet Microscopy using 3D-printed Freeform Optics
Authors: Taege Yanis , Schulz Sophia Laura , Messerschmidt Bernhard , Eggeling Christian , Ataman Çağlar
Published: September 2022

Intended for Airy light-sheet microscopy, we design and implement a miniaturized illumination unit only 25 mm in length, which incorporates a 3D-printed refractive cubic phase mask.
Design of a Tapered Few-Mode Fiber based Broadband Mode Coupler for Multimode OCT
Authors: Hu Dora Juan Juan , Liu Linbo , Dong Hui , Zhang Hailiang
Published: September 2022

This paper presents a design and simulation study of a tapered few-mode fiber based broadband mode coupler for multimode optical coherence tomography in the O-band for better signal collection efficiency and improved penetration depth.
Improved Spectral Purity of Burst-Mode Laser for Filtered Rayleigh Scattering Applications
Authors: Braun Amanda M. , Slipchenko Mikhail N. , Meyer Terrence R. , Danehy Paul M. , Roy Sukesh
Published: September 2022

High spectral purity of the laser source in Filtered Rayleigh Scattering (FRS) is necessary to remove stray scattering. In this study, the spectral purity of a burst-mode laser was improved to 0.9999987 using an etalon
CO2 energy distributions in a nonequilibrium discharge using fs/ps CARS
Authors: Thompson Ryan J. , Dedic Chloe E.
Published: September 2022

Recently-developed hybrid fs/ps CARS models of CO2 and CO are compared to experimental spectra taken within a flame and nonequilibrium plasma. The sensitivity to nonequilibrium and accuracy of the models are evaluated.
Faraday enhanced dual comb spectroscopy with Fabry-Perot quantum cascade lasers at 8um
Authors: Patrick Link , Wysocki Gerard
Published: September 2022

Faraday rotation measurement is used in conjunction with dual comb spectroscopy with Fabry-Perot quantum cascade lasers at 8 μm. The lasers have a spectral resolution on the order of 10 kHz while the measurement spectrum covers over 80 wavenumbers.
Chirp-probe-pulse femtosecond coherent anti-Stokes Raman scattering for gas-phase temperature measurements: Application to high-pressure kerosene/air combustion
Authors: Legros S. , Caceres M. , Barviau B. , Grisch F.
Published: September 2022

This paper illustrates the use of chirped-probe-pulse fs-CARS thermometry in combination with a high-pressure optical test rig for lean-burn combustor development. Temperature measurements were performed at 1 kHz in kerosene/air combustion at 0.75 MPa.
Fast optical determination of enantiomeric excess using photoelectron elliptical dichroism
Authors: Comby A. , Descamps D. , Petit S. , Blanchet V. , Mairesse Y.
Published: September 2022

We present a solution based on intense laser-matter interaction that is able to determine quickly and accurately the enantiomeric excess (99.8% accuracy in 3 min) for a large set of chiral chemical sample.
Quantitative in-situ Raman spectroscopy for gas and liquid phase catalytic reactions
Authors: Yang Chaobo , Wang Haoyi , Huang Liang , Sarathy S. Mani , Lu Xu , Magnotti Gaetano
Published: September 2022

We demonstrate an application of Raman spectroscopy for in-situ measurements of gas and liquid phase catalytic reactions. After a hybrid fitting and integrating processing, the Raman spectra provide quantitative information of the near-surface region.
Flame Chemiluminescence Sensing and Analysis for Scramjet Control
Authors: Elkowitz Laurie , Goyne Christopher P. , Dedic Chloe E.
Published: September 2022

Optical emission spectroscopy and filtered high-speed imaging of OH*, CH* and C2* chemiluminescence is measured the combustor of a scramjet engine to explore its use as a flight control sensor.
Non-hogel-based computer generated hologram with occlusion processing between the foreground light field and background hologram
Authors: Min Dabin , Min Kyosik , Choi Hee-Jin , Lee Hanul , Park Jae-Hyeung
Published: September 2022

A novel technique is proposed to process the occlusion of a background hologram when synthesizing a front scene hologram from its light field. Unlike conventional techniques which process the occlusion in the light field domain after converting the background hologram to its light field, the proposed technique directly processes the occlusion between different domains, i.e., the background hologram and foreground light field. The key idea is to consider the background hologram as a carrier wave illuminating the front scene when synthesizing the front scene hologram from its light field. The proposed technique is not only computationally efficient as it does not require conversion between the light field and hologram domains but also accurate because all angular information of the background hologram and foreground light field is naturally considered in the occlusion processing. The proposed technique was verified by numerical synthesis and reconstruction.
Phase estimation of an SU(1,1) interferometer with a coherent superposition squeezed vacuum in a realistic case
Authors: Xu Youke , Chang Shoukang , Liu Cunjin , Hu Liyun , Liu Sanqiu
Published: September 2022

The phase sensitivity of SU(1,1) interferometer is investigated using a coherent state and an m-coherent superposition squeezed vacuum states as inputs and the intensity detection. Photon-subtraction, photon-addition and photon superposition are three special cases. Both ideal and realistic cases are considered. It is shown that the coefficient s of coherent superposition can modulate the performance of phase sensitivity, especially in a small squeezing region. Even in the presence of photon losses, the three-kind of non-Gaussian operations can achieve the improvement of measure precision, and the photon addition presents the best robustness compared to the photon subtraction and coherent superposition. For small squeezing, the first-order non-Gaussian operation may be the most preferred in improving phase sensitivity if considering the limitations of experimental conditions. Our results may be helpful for the practical application of quantum information.
Multimode fiber surface plasmon resonance sensor based on a down–up taper
Authors: Jin Bingjie , Wang D. N.
Published: September 2022

A multimode fiber surface plasmon resonance sensor based on a down–up taper for refractive index measurement is proposed and demonstrated. The device is fabricated by splicing two multimode fibers in a heating and pushing process to form an up taper, followed by heating and pulling the fiber adjacent to the up-taper area to form a down taper, and then using a magnetron sputtering technique to deposit a Cr + Ag layer of 50 nm on the surface of the down–up taper. Such a structure effectively increases the taper ratio and hence improves the measurement sensitivity. The experimental results obtained show that in the refractive index range of 1.345–1.375, the refractive index sensitivity achieved is ∼3264.01 nm/RIU. The device has a compact size and its entire length is ∼2.75 mm. Moreover, the robustness of the device is better than that of the previously reported fiber surface plasmon resonance sensors due to its relatively large waist diameter of 40 µm for the down taper. The device is expected to have potential applications in biological and chemical sensing.
Strengthening optical enhancement with AgxAu1−x alloy and Ag/Au heteromaterial sub-micro disk arrays
Authors: Sitpathom Nonthanan , Suwanna Sujin , Pijitrojana Wanchai , Infahsaeng Yingyot , Pongophas Ekkarat , Bavontaweepanya Ruchipas , Deesuwan Tanapat
Published: September 2022

Material modification on plasmonic nanostructures is recognized as one of many approaches to increase optical near-field enhancement and resonance wavelength tuning. In this work, with finite-difference time-domain simulation, we showed that closed-hexagonal sub-micro disk arrays of the Ag
x
Au1−x alloy increase electric-field enhancement in the near-infrared spectra at reduced Ag fraction in the alloy, while the arrays of pure Ag does so in the visible spectra. For the enhancement factor in the near-infrared region, the Au array is dominant around the wavelength of 800 nm, whereas the Ag0.74Au0.24 array is slightly stronger at 820 nm. Furthermore, the local confinement in the near-infrared region (800-900 nm) is strengthened by the heteromaterial array of Ag/Au sub-micro disks with alternating rows, which can boost the electric field enhancement at 1.3 and 3.9 times better than those of the pure Au and Ag arrays, respectively. The Ag, Au and Ag/Au plasmonic hexagonal arrays yield the Purcell factors of 2.42 × 105, 1.17 × 104 and 2.72 × 104, respectively, at wavelengths of 695 nm, 828 nm and 795 nm that would be suitable for spontaneous emission rate enhancement in quantum dots.
High-sensitivity frequency comb carrier-envelope-phase metrology in solid state high harmonic generation
Authors: Lesko Daniel M. B. , Chang Kristina F. , Diddams Scott A.
Published: September 2022

Non-perturbative and phase-sensitive light–matter interactions have led to the generation of attosecond pulses of light and the control of electrical currents on the same time scale. Traditionally, probing these effects via high harmonic generation has involved complicated lasers and apparatuses to generate the few-cycle and high peak power pulses needed to obtain and measure spectra that are sensitive to the phase of the light wave. Instead, we show that nonlinear effects dependent on the carrier-envelope phase can be accessed in solid state crystals with simple, low pulse energy frequency combs that we combine with high-sensitivity demodulation techniques to measure harmonic spectral modulations. Central to this advance is the use of a scalable 100 MHz erbium-fiber frequency comb at 1550 nm to produce 12 nJ, 20 fs pulses that are focused to the

T
W

/

c
m

2

level. In a single pass through a 500 µm ZnO crystal, this yields harmonic spectra extending down to 200 nm. With this system, we introduce a technique of carrier-envelope amplitude modulation spectroscopy (CAMS) and use it to characterize the phase-sensitive modulation of the ultraviolet harmonics with an 85 dB signal-to-noise ratio. We further verify the non-perturbative nature of the harmonic generation through polarization gating of the driving pulse to increase the effects of the carrier-envelope phase. This work demonstrates robust and ultra-sensitive methods for generating and characterizing harmonic generation at 100 MHz rates that should provide advantages in the study of attosecond nonlinear processes in solid state systems. Additionally, as a simple and low-noise frequency comb, this broadband source will be useful for precision dual-comb spectroscopy of a range of physical systems across the ultraviolet and visible spectral regions (200–650 nm).
Image-plane scintillation of complex targets in diverse heterogenous turbulent regimes
Authors: Pérez Darío G. , Sepúlveda Marco , Nuñez Leandro
Published: September 2022

We have previously reported [D. G. Perez et al., Imaging Appl. Opt. 2019 (pcAOP), invited talk] that image-plane scintillation index can provide a universal law to extract

C
n
2

—independent of the target shape and light source. Also, we observed

σ
l
2

>
1

on the image plane occurs at any turbulence strength; particularly, as we move from weak to strong optical turbulence the number of pixels with scintillation greater than one increases in the neighborhood of high-contrast regions (edges). As the number of pixels with large scintillation values is observed with higher frequency in targets illuminated with incoherent light, whether wandering plays a mayor influence or not in image-plane scintillation regardless of the turbulent regime is still unknown. In this communication, we have devised a new experiment capable of differentiating the contributions of amplitude and phase to the pixel scintillation. Moreover, structured targets were introduced to distinguish anisotropic regimes, a property that was largely undetected in our original setup.
Techniques to Quantify Ambient Aerosol Optical Properties from Measurements of Extinction and Scattering
Authors: Fiorino Steven , Rinaldi Benjamin , Keefer Kevin , McCrae Jack
Published: September 2022

In this paper we describe methods to obtain bulk aerosol real and imaginary refractive index (RI) components from measurements of scattering and absorption. Results suggest existing databases of aerosol RI may be reasonable first estimates.
Collimated Gaussian Beam Size: Near-Field and Far-Field Approximations
Authors: Andrews Larry , Beason Melissa
Published: September 2022

Spot radius is dependent upon whether the receiver is in the near or far field which becomes significant when considering beam skewness. We compare methods to calculate beam radii, impact on skewness, and suggest an empirical method to transition between regimes.
Optimal Beams and Minimizing Scintillation
Authors: Li Qin , Nair Anjali , Stechmann Samuel N
Published: September 2022

Computation of optical beams which minimize scintillation is a difficult challenge. Here, a computationally feasible method is described, and scintillation-minimizing beams are shown to have very weak intensity. Optimization should consider both scintillation and intensity.
Computation of Optimal Beams in Weak Turbulence
Authors: Li Qin , Nair Anjali , Stechmann Samuel N
Published: September 2022

Finding general beams that maximize intensity leads to eigenvalue problem of a large matrix, with each entry being a multi-dimensional integral. We provide a computational strategy in Fourier space that makes this problem numerically feasible.
Towards Online Monitoring of Radiation Dose with TS-doped PMMA Fibre
Authors: Olusoji Olugbenga J. , Kam Wern , Cheng Xin , Woulfe Peter , Tam Hwa-Yaw , O’Keeffe Sinead
Published: September 2022

Doping of polymethyl-methacrylate (PMMA) polymer optical fibre (POF) with Trans-4-stilbenemethanol (TS) increases the sensitivity to radiation by a factor of over two. The potential of step index TS doped PMMA POF for online radiation monitoring is reported.
Fibre Bragg Grating Optical Fibre Sensors Application for Strain Monitorisation in Pultruded Smart FRP Beams
Authors: Maldonado-Hurtado Daniel , Madrigal Javier , Ruiz Rocío , Crespo Ana Isabel , Sales Salvador
Published: September 2022

We successfully embedded optical sensors based on fibre Bragg gratings in a fibre reinforced polymer pultrusion beam for strain monitoring. Tests results showed up to 7500 µstrains transmitted from the test beam to the sensors.
A Microturbine Flow Sensor Created on an Optical Fiber Tip Using Multiphoton Nanomachining Process
Authors: Williams Jeremiah C. , Chandrahalim Hengky , Suelzer Joseph S. , Usechak Nicholas G.
Published: September 2022

We report a microturbine flow sensor built onto the tip of an optical fiber by multiphoton nanomachining process. A dynamic microturbine is engineered to reflect light in response to incident fluid flow.
Plastic Scintillation Fibre Dosimetry for Monitoring of External Beam Radiation Therapy
Authors: Kam W. , Martyn M. , Olusoji O. J. , Woulfe P. , O’Keeffe S.
Published: September 2022

This work presents the feasibility of Kuraray’s plastic scintillator based fibre for monitoring external beam radiation therapy. The sensor was investigated within a clinical linac for different energies, dose rates and field sizes for comparison.
Development of a Wearable Optoelectronic Pressure Sensor Based on the Bending Loss of Plastic Optical Fiber and Polydimethylsiloxane
Authors: Romero Alberto Alonso , Amouzou Koffi , Richard-Denis Andréane , Mac-Thiong Jean-Marc , Petit Yvan , Lina Jean-Marc , Ung Bora
Published: September 2022

We designed and demonstrated a PDMS-based flexible pressure sensor based on plastic optical fibers for measuring pressures up to 3820 mmHg with good repeatability. Its potential applications include wearable sensors for prevention of pressure injuries.
Versatile Superlattice-enhanced Quantum Sensing
Authors: Toa Zi S.D. , Paterova Anna V. , Chekhova Maria V. , Krivitsky Leonid A.
Published: September 2022

Versatile and sensitive quantum sensors are important in various applications. A crystal superlattice is capable of sensitively measure low and high infrared analyte concentration by respectively measuring fringe maximum intensity and visibility in the visible.
Enhanced Dynamic Range of an Interferometric Pindisk Biosensor by Intensity Based Sensing
Authors: Bläsi Johannes , Köpke Markus , Gerken Martina
Published: September 2022

Pindisk arrays are used in multi-pinhole interferometric phase detection setups. Here, we show that the integration of an intensity-based resonance shift measurement into the interferometric pindisk setup increases the dynamic range of the overall system.
Nanostructured Floes on PDMS as a Basis for Strain-Invariant Photonic-Crystal Slabs
Authors: Kraft Fabio A. , Gerken Martina
Published: September 2022

Photonic-crystal slabs processed on PDMS form floes with fractures inbetween. These absorb mechanical strain stabilizing their optical properties. A chromatic-shift-to-strain ratio of 0.62 nm/% strain is observed compared to 3.9 nm/% strain with standard flexible gratings.
A New Detecting Mechanism of Single-Molecule Optoplasmonic Sensors
Authors: Toropov Nikita , Houghton Matthew , Yu Deshui , Vollmer Frank
Published: September 2022

Single-molecule sensors based on the whispering-gallery modes coupled to plasmonic resonant systems are studied. We reveal the changes of the reactive sensing mechanisms under different intensities of modes – anomalous decrease of the resonant mode wavelength.
Two-Dimensional Electronic Spectroscopy reveals liquid like structural dynamics in semiconductor perovskites
Authors: Seiler Helene , Brosseau Patrick , Strandell Dallas , Kambhampati Patanjali
Published: September 2022

Two-Dimensional Electronic (2DE) spectroscopy is performed on bulk nanocrystals of semiconductor perovskites of two different classes. The anti-diagonal linewidths reveal liquid like structural dynamics due to ultrafast polaron formation on the 300 fs timescale.
Multispectral Two-Dimensional Electronic Spectroscopy of the Photosystem II Reaction Center
Authors: Nguyen Hoang H. , Song Yin , Maret Elizabeth L. , Silori Yogita , Ogilvie Jennifer P.
Published: September 2022

We present two-dimensional electronic spectroscopy of the photosystem II reaction center at 77K, exciting the spectrally-congested Qy region and probing multiple spectral regions spanning the visible to the mid-IR to extract broadband charge separation signatures.
Femtosecond UV photochemistry of the biologically relevant L-cysteine disulfide moiety in aqueous solution investigated by time-resolved X-ray absorption spectroscopy
Authors: Ochmann Miguel , Harich Jessica , Ma Rory , Freibert Antonia , Lee Jae Hyuk , Nam Daewoong , Kim Sangsoo , Eom Intae , Kim Minseok , Kim Yujin , Gopannagari Mahusudana , Hong Dae Hye , Kim Tae Kyu , Huse Nils
Published: September 2022

Femtosecond X-ray absorption spectroscopy of the disulfide bridge in L-cystine reveals the thyil radical as the only primary photoproduct which geminately recombines in an ultrafast solvent cage-mediated process, leading to the long-lived perthyil radical.
Revealing the Geometric Phase Effects Around Conical Intersections in Molecules by High-order Harmonic Spectroscopy
Authors: Yuan Guanglu , Jiang Shicheng , Lu Ruifeng , Dorfman Konstantin
Published: September 2022

We theoretically established a multi-potential energy surface model of the molecule under the diabatic representation, and proposed a scheme to probe the geometric phase effect around the conical intersection by using high-order harmonic spectroscopy.