bluuebunny/crossref_metadata_2025 huggingface dataset:
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG
Authors: Li Qian , Yang Li , Zhang Feng , Liu Jiaxi , Jiang Min , Chen Yannan , Ren Chenchen
Published: November 2022

In brief

Inflammation and abnormal immune response are the key processes in the development of endometriosis (EMs), and m6A modification can regulate the inflammatory response. This study reveals that METTL3-mediated N6-methyladenosine (m6A) modification plays an important role in EMs.

m6A modification is largely involved in the development of different diseases. This study intended to investigate the implication of m6A methylation transferase methyltransferase like 3 (METTL3) in EMs. EMs- and m6A-related mRNAs and long non-coding RNAs were identified through bioinformatics analysis. Next, EM mouse models established by endometrial autotransplantation and mouse endometrial stromal cell (mESC) were prepared and treated with oe-METTL3 or sh-MIR17HG for pinpointing the in vitro and in vivo effects of METTL3 on EMs in relation to MIR17HG through the determination of mESC biological processes as well as estradiol (E2) and related lipoprotein levels. We demonstrated that METTL3 and MIR17HG were downregulated in the EMs mouse model. Overexpression of METTL3 suppressed the proliferation, migration, and invasion of mESCs. In addition, METTL3 enhanced the expression of MIR17HG through m6A modification. Moreover, METTL3 could inhibit the E2 level and alter related lipoprotein levels in EMs mice through the upregulation of MIR17HG. The present study highlighted that the m6A methylation transferase METTL3 prevents EMs progression by upregulating MIR17HG expression.
Lithogeochemistry of black shales of the Phanerozoic of the Western Ukraine ‒ unconventional hydrocarbon reservoirs
Authors: Popp Ihor , Moroz Petro , Shapovalov Mykhaylo
Published: November 2022

The purpose of this work is to compare the lithological, geochemical and mineralogical features of carbonaceous clayey and siliceous-clay rocks of Cretaceous-Paleogene flysch of the Ukrainian Carpathians and Lower Silurian of the Volyn-Podillya edge of the East European Platform and to determine the factors that contributed to the formation of zones of “unconventional reservoirs” in these sedimentary strata of cracked and mixed types. Data from the lithology, geochemistry and mineralogy of bituminous siliceous-clay rocks and siliceous rocks of Lower Cretaceous and Oligocene of the Carpathians and black argillites of Lower Silurian of the Volyn-Podillya edge of the East European Platform are presented. Sedimentogenesis of Lower Cretaceous and Oligocene bituminous deposits of the Carpathians and Lower Silurian deposits of Volyn-Podillya took place in anoxic conditions (phases of oceanic anoxic events: OAE-1 (Barrem–Albian), OAE-4 (Oligocene) and at the border of Ordovician and Silurian. Paleoceanographic conditions of their sedimentation differed significantly. The first are deep-sea formations at the foot of the continental slope of the Carpathian segment of the Tethys Ocean, the second were accumulated in the warm shallow sea on the eastern shelf of the West European Sea Basin. The layered texture of carbonaceous deposits, as well as the catagenetic transformation of rock-forming clay and siliceous minerals and their hydrophobization, played a significant role in the formation of the filtration capacity properties of “unconventional reservoirs”. In Cretaceous-Paleogene flysch deposits of the Carpathians, “unconventional reservoirs” are usually terrigenous-clay or siliceous-clay rocks with shale and layered texture or compacted sandstones localized in conventional oil, gas or condensate deposits. Lower Silurian clay deposits of Volyn-Podillya are promising for the search for “shale gas”.
Chronic Iron Deficiency and Cognitive Function in Early Childhood
Authors: Gingoyon Argie , Borkhoff Cornelia M. , Koroshegyi Christine , Mamak Eva , Birken Catherine S. , Maguire Jonathon L. , Fehlings Darcy , Macarthur Colin , Parkin Patricia C.
Published: November 2022

BACKGROUND AND OBJECTIVES

A landmark longitudinal study, conducted in Costa Rica in the 1980s, found that children with chronic iron deficiency compared with good iron status in infancy had 8 to 9 points lower cognitive scores, up to 19 years of age. Our objective was to examine this association in a contemporary, high-resource setting.

METHODS

This was a prospective observational study of children aged 12 to 40 months screened with hemoglobin and serum ferritin. All parents received diet advice; children received oral iron according to iron status. After 4 months, children were grouped as: chronic iron deficiency (iron deficiency anemia at baseline or persistent nonanemic iron deficiency) or iron sufficiency (IS) (IS at baseline or resolved nonanemic iron deficiency). Outcomes measured at 4 and 12 months included the Early Learning Composite (from the Mullen Scales of Early Learning) and serum ferritin.

RESULTS

Of 1478 children screened, 116 were included (41 chronic, 75 sufficient). Using multivariable analyses, the mean between-group differences in the Early Learning Composite at 4 months was −6.4 points (95% confidence interval [CI]: −12.4 to −0.3, P = .04) and at 12 months was −7.4 points (95% CI: −14.0 to −0.8, P = .03). The mean between-group differences in serum ferritin at 4 months was 14.3 μg/L (95% CI: 1.3–27.4, P = .03) and was not significantly different at 12 months.

CONCLUSIONS

Children with chronic iron deficiency, compared with children with IS, demonstrated improved iron status, but cognitive scores 6 to 7 points lower 4 and 12 months after intervention. Future research may examine outcomes of a screening strategy on the basis of early detection of iron deficiency using serum ferritin.
The Role of Renal Artery Embolisation in the Management of Blunt Renal Injuries: A Review
Authors: Ho Rosemary Denning , Shrivastava Vivek , Mokhtari Amir , Lakshminarayan Raghuram
Published: November 2022

Renal injuries are the most common urinary tract injury secondary to external abdominal trauma. They are caused by blunt, penetrating and iatrogenic mechanisms. Despite the high number of blunt renal injuries, little evidence is available to guide management, especially with the evolution of embolisation as a minimally invasive treatment. Consequently, clinical practice is driven by results of observational studies and anecdote. We have reviewed the current trends in practice when using renal artery embolisation in the management of blunt renal injuries. Three key principles are highlighted. First, high-grade blunt renal injuries can be successfully managed with embolisation. Second, embolisation should be considered when there is radiological evidence of active contrast extravasation, pseudoaneurysm or arteriovenous fistula. Third, embolisation can be used to manage blunt renal injuries in haemodynamically unstable patients. Beyond this, evidence regarding optimal technique, CT indications, clinical status, comorbidities and complications are inconclusive. We discuss the implications for clinical practice and how these findings should define the agenda for future clinical research.
Winograd schemata and other datasets for anaphora resolution in Hungarian
Authors: Vadász Noémi , Ligeti-Nagy Noémi
Published: November 2022

The Winograd Schema Challenge (WSC, proposed by Levesque, Davis & Morgenstern 2012) is considered to be the novel Turing Test to examine machine intelligence. Winograd schema questions require the resolution of anaphora with the help of world knowledge and commonsense reasoning. Anaphora resolution is itself an important and difficult issue in natural language processing, therefore, many other datasets have been created to address this issue. In this paper we look into the Winograd schemata and other Winograd-like datasets and the translations of the schemata to other languages, such as Chinese, French and Portuguese. We present the Hungarian translation of the original Winograd schemata and a parallel corpus of all the translations of the schemata currently available. We also adapted some other anaphora resolution datasets to Hungarian. We aim to discuss the challenges we faced during the translation/adaption process.
Integración de herramientas para la evaluación de indicadores de publicaciones científicas
Authors: González-Sanabria Juan-Sebastián , Verdú-Pérez Elena , Blanco-Valencia Xiomara-Patricia , Herrera-Melo Camila-Andrea , Serna-Vargas Julián-Camilo
Published: November 2022

Cada vez son más las herramientas tecnológicas que surgen cada día para ayudar en la gestión de los procesos editoriales que lleva una revista científica, desde el envío de un trabajo hasta su publicación y seguimiento de citas. Sin embargo, dado este incremento de opciones se vuelve más complejo para los responsables hacer un adecuado seguimiento y validación de los procesos, pues la información se encuentra más dispersa y en varias oportunidades carecen de interoperabilidad entre ellas. En el presente trabajo se propone una arquitectura de integración de las diferentes herramientas mínimas necesarias para el flujo editorial, haciendo una comparación analítica y técnica, que permita obtener done se presenta la mejor integración de estas, lo que permita simplificar en una única plataforma toda la información requerida. Como resultado se presenta un primer prototipo de plataforma aplicando la arquitectura definida, obteniendo resultados favorables para el seguimiento y validación de los trabajos e indicadores de las revistas.
Az Arktisz mint a magyar biztonságpolitika új kitörési pontja?
Authors: Molnár Dóra , Szalkai Patrik
Published: November 2022

A tanulmányban a szerzők arra a kérdésre keresik a választ, hogy Magyarországarktiszi érdekeltségének van-e, illetve lehet-e alapja. Ehhez segítségül hívják egyrészta hatályos stratégiai dokumentumokban foglaltakat, amelyekben már most is vanhomályos utalás az arktiszi érdekek artikulációjára, másrészt pedig – bemutatva a bilaterálisegyüttműködések fő szereplőit és területeit – feltárják a magyar jelenlétet.Mindez jó alap lehet a következő évtized(ek) továbblépéséhez, amelyhez megfelelőeszköz lehet a regionális szervezetekben – és mindenekelőtt az Arktiszi Tanácsban –való magyar megfigyelői státusz elnyerése.
Posztmodern elrettentés
Authors: Várdai Mihail Istvanovics
Published: November 2022

A hidegháború lezárását követően, a nagyhatalmak nukleáris szembenállása, a különbözőleszerelési, fegyverzet-ellenőrzési és foganatosított bizalom- és biztonságerősítőintézkedései következtében mérséklődött. Ez az eseménysor egybeesik azzal az ugrásszerűtechnikai fejlődéssel, aminek köszönhetően olyan új fegyverrendszerek jelentekmeg, amelyek bizonyos jellegű bevetésének következtében akár úgynevezett lefejezőcsapást is lehet mérni. Ez a technikai fejlődés a 21. században felgyorsult, és korábbanelképzelhetetlen fegyverrendszerek jelentek meg. Az elrettentés ennek a technikai fejlődésnekkövetkeztében átalakulóban van, viszont az alapelvek ennek ellenére nemváltoztak. A nukleáris fegyverek elrettentési potenciálja továbbra is jelentős, viszonta forradalmi technológiák elérhetősége következtében bizonyos új fegyverrendszerekproliferációja a nemzetközi biztonsági környezetre jelentős hatásokkal bírhat. A forradalmitechnológiák rendelkezésre állnak mind az állami, mind a nem állami szereplőkrészére és ezek katonai célú alkalmazása következtében új szereplők jelentek meg.
Társadalmi megosztottság és a politikai pártok az Egyesült Államokban
Authors: Matus János
Published: November 2022

A nemzetközi biztonság problémáinak megértését az orosz–ukrán háború új megvilágításbahelyezte. Nyilvánvalóvá vált, hogy egy állam – a nemzetközi rendszerben tanúsított– magatartását a belső politikai, gazdasági és társadalmi folyamatok, továbbáa döntéshozókra gyakorolt hatások erőteljesen befolyásolják. Az is belátható, hogy a fokozódóbelső pártküzdelmek összefüggésbe hozhatók a nemzetközi biztonsággal. Ebbőlfakadóan célszerűnek tartjuk – különösen a nemzetközi stabilitást befolyásoló nagyhatalmakesetében – külpolitikájukra hatást gyakorló belpolitikai folyamatok elemzését.Ez a tanulmány a fenti gondolat jegyében az Egyesült Államok belpolitikai folyamataitteszi vizsgálat tárgyává. Elemzi a két meghatározó politikai párt stratégiájának változásaités azok támogatottságát a közvéleményben. Végül rámutat a dilemmára, amely a két pártbelső átalakulása, a generációváltás és a szavazói magatartás bizonytalanságai miatt azEgyesült Államok kül- és biztonságpolitikai magatartásának a megítélésében keletkezhet.
Rotación de personal en una empresa procesadora de alimentos: tasa de rotación y motivos
Authors: Hernández Hernández Rafael Ángel , Durán-Rojas Elvira
Published: November 2022

Objetivo: Esta investigación tuvo como finalidad analizar los motivos que incidieron en la rotación del personal en una empresa de alimentos colombiana para la mejora en el reclutamiento y retención de los empleados. Método: Se desarrolló un estudio descriptivo, longitudinal, retrospectivo y transversal de enfoque mixto, donde para la recopilación de la información se aplicaron las técnicas de la entrevista semiestructurada y la encuesta. Resultados: se encontró que los motivos de mayor influencia en la rotación de personal según la empresa corresponden al tipo de vinculación laboral y al cargo; y según los desvinculados a la carga de trabajo, salario, horarios laborales, desmotivación, insatisfacción y oportunidad de ascenso. Conclusiones: Se constituye la satisfacción y el tipo de contratación como aquellas dimensiones a tener en cuenta para minimizar la rotación de personal y generar un mejor bienestar.
Riesgo de consumo de sustancias psicoactivas y su relación con el uso problemático de videojuegos y redes sociales en estudiantes universitarios
Authors: Mejia Lobo Mauricio , González-Cortés Jorge-Hernán , Rincón-Barreto Dubis-Marcela
Published: November 2022

Introducción: El nivel de riesgo de consumo se establece a partir de la exposición que tiene una persona a ciertos factores de riesgo o características individuales, familiares o sociales, que posibilitan o aumentan el consumo de sustancias psicoactivas (SPA).
Objetivo: Este estudio tuvo como propósito relacionar el nivel de riesgo de consumo de SPA con el uso problemático de videojuegos y redes sociales, a fin de establecer su posible papel como factores de riesgo de tipo social.
Método: Se realizó un estudio de tipo cuantitativo con un diseño no experimental transversal de alcance descriptivo correlacional con la participación de 736 estudiantes. Se emplearon como instrumentos de recolección de datos el cuestionario sociodemográfico, prueba de tamizaje ASSIST 3,1, cuestionario de adicción a redes sociales – ARS y el cuestionario de Experiencias Relacionadas con los Videojuegos – CERV.
Resultados: Algunos resultados sugieren mayor exposición al consumo de sustancias alcohólicas, derivados del tabaco, del cannabis y mayores niveles en el uso problemático de redes sociales y videojuegos.
Conclusiones: A partir de lo hallado, las evidencias apuntan a que el aumento de riesgo no depende de la tipología familiar, al contrario de lo que pasa con el sexo, a su vez el consumo de tabaco, alcohol, cocaína, inhalantes, sedantes y opiáceos dependen de variaciones.
Forest restoration and Sustainable of Soil Water Resources and High-quality sustainable management
Authors: Zhongsheng Guo
Published: November 2022

Along with economic development and an increase in population, there is an increasing demand for goods such as timber, food, medicine, and so on, and ecological services such as fresh water and the environment. Because goods and service produced by the original forest cannot meet the increasing need of people, so most of the original forest has become farmland, plantation, and grass, and a lot of exotic plants was introduced to produce special products and service. As introduced plants grow, vegetation decline and crop failure happen in dry years or resource waste in wet years. In order to solve these problems, Years of theoretical research and investigation in fixed positions have shown that there is a soil water resources use limit by plants and the soil water vegetation carrying capacity in the process of vegetation restoration. When the soil water resources in the range of the maximum infiltration depth are equal to soil water resources use limit by plants, the plant water relation enters the key period of plant water relation regulation. If existing plant density is more than the soil water vegetation carrying capacity in the key period of plant water relation regulation, the plant water relation has to be regulated on the soil water vegetation carrying capacity to get maximal yield and service and realize high-quality sustainable management of forest vegetation in a water shortage area.
Bacteriological pattern of urinary tract infection in men with symptomatic benign prostatic hyperplasia at a tertiary hospital in Nigeria
Authors: Ngwu PE , Ihedoro IE , Kalu EI
Published: November 2022

Introduction/Background: Benign Prostatic Hyperplasia (BPH) is characterized by narrowing of the prostatic urethra with resultant difficulty in passing urine, stasis, and a predisposition to urinary tract infection. The objective of this study is to identify the prevalence of urinary tract infections, common organisms isolated, their antimicrobial sensitivity pattern, and the relationship of co-morbidities with urinary tract infection in this population. Materials and methods: All patients who presented to our urology team with bladder outlet obstruction secondary to benign prostatic hyperplasia between January 2020 and January 2021 were included. Information on age, occupation, co-morbid conditions, urine microscopy, culture, and sensitivity patterns were obtained and analyzed using SPSS version 25. Midstream urine samples were collected from 172 BPH patients. Microscopy, culture, and antibiotic susceptibility tests were carried out. Results: From our study, the prevalence of bacteriuria was 67.9% with the 65-74 and 45-54 age groups having the highest and the least prevalence of bacteriuria (88.9% and 33.3% respectively). The most common organisms cultured from their urine were Pseudomonas (17.9%), E. coli (14.3%), Coliforms (10.7%), and Klebsiella (10.7%). Sensitivity patterns of these microorganisms revealed the highest sensitivity to the fluoroquinolones (25.9%) followed by Nitrofurantoin (14.8%) and Ceftriaxone and Cefoxitin (7.4%). The least sensitivity was to Augmentin and Gentamycin. Conclusion: Bacteriuria is common in patients with BPH. Pseudomonas spp was the commonest isolated organism in our study and most isolated organisms were susceptible to the fluoroquinolones.
A Survey on Intrabody Communication Modeling Methods
Authors:   National Research University Higher School of Economics (HSE), Moscow, Russian Federation, Khromov I. A. , Voskov L. S. ,   National Research University Higher School of Economics (HSE), Moscow, Russian Federation
Published: November 2022

Wireless body area network (WBAN) provides energy-efficient data transfer between wearable devices. Traditional WBAN consists of large and high-power consumption devices. Intrabody communication (IBC) is one of the technologies used by WBAN. IBC transmits data within the human body, consisting of different tissues. When developing devices for WBAN, modeling is necessary due to the signal transmission within complex layer structures. In this paper, a comprehensive IBC modeling overview has been introduced. Our investigation collected, classified and evaluated modeling methods for various body tissues. The WBAN development and modeling problems, and the main requirements for their design are considered.
Planning and the High-Rise Neighbourhood: Debates on Vertical Cities
Authors: Webb Brian , White James T.
Published: November 2022

This editorial introduces the thematic issue on “Vertical Cities: The Development of High-Rise Neighbourhoods.” It outlines the lack of understanding about high-rise development in cities around the world and argues for a continued need to further interrogate concepts of verticality beyond single towers and towards a finer grain examination of high-rise neighbourhoods. The editorial introduces four interconnected themes that begin to address this phenomenon—socio-demographic challenges, planning discourses, high-rise legacies, and alternative conceptions of verticality—and highlights how the various articles in this thematic issue explore these critical areas of enquiry. It concludes with a call for future research to delve deeper into the planning challenges presented by high-rise neighbourhoods in the 21st-century city and, critically, the contribution that high-rise urban form makes to urban sustainability.
EXPERIENCE OF ISOTOPE TECHNOLOGIES APPLICATION TO STUDY CHANGES IN DEEP-WATER POTABLE AQUIFERS STATE WITHIN KYIV IN CONDITIONS OF LONG-TERM OPERATION
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Koshliakov О. , Koshliakova Т. ,   M.P. Semenenko Institute of Geochemistry, Mineralogy and Ore Formation of the NAS of Ukraine, Kyiv, Ukraine, Dyniak О. ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Koshliakova І. ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: November 2022

The presented research is devoted to study and establishment of the spatiotemporal change of tritium content in groundwater of CenomanianCallovian groundwater complex in Kyiv and the causes of these changes in order to identify water exchange features and hydraulic interaction between shallow and deep aquifers, as well as between groundwater and surface waters. Due to the excessive use of groundwater, depressive surfaces of hydrodynamic pressures have formed, aquifers are transforming from pressure head to pressureless, and there is a danger of downward filtration and contamination of potable groundwater. Also, one of the effects of these depressions formation is deterioration of water quality. However, to study the conditions of the qualitative composition formation of deep potable aquifers and to identify the causes of changes in groundwater status is a difficult and responsible task at the same time. Methods of isotopic hydrogeology are among the main scientific methods used to track the peculiarities of groundwater movement and assess their age. The new data obtained by isotopic methods help to control water resources and allow to make such decisions that will bring socio-economic benefits. The obtained data of tritium content in groundwater of Cenomanian-Callovian groundwater complex, clearly presented in the form of maps, allow to make informed decisions on sustainable resource management, and regular monitoring of chemical and isotopic composition of groundwater reveals mechanisms of recharge and sources of pollution, which were not taken into account before. The results obtained by the authors through statistical and spatial analysis of tritium content in groundwater during 2014-2017, indicate that currently within the territory of Kyiv there is a positive trend towards a slow gradual return of Cenomanian-Callovian groundwater complex to its natural state.
Predictions of the 1997 strong earthquakes in Jiashi, Xinjiang, China
Authors: Zhang Guomin , Zhu Lingren , Song Xiaodong , Li Zhixiong , Yang Maling , Su Naiqin , Chen Xuezhong
Published: November 2022

A sequence of strong earthquakes occurred in Jiashi County, Xinjiang, China (40°N, 77°E, population 280,000) in 1997, after a 10-month quiescence following a Ms 6.9 earthquake on 19 March 1996 in the same area. From 21 January 1997, through 18 October 1997, 15 earthquakes occurred with Ms ≥ 5.0, seven of which with Ms ≥ 6.0. Such sequences of strong earthquakes are rare around the world, but have occurred six times in the land area of China during this century. Of the 15 Ms ≥ 5.0 earthquakes in the Jiashi sequence, eight fell within the predicted 7-day time windows of a total of 8 short-term and imminent-stage predictions, but the initial shocks of the sequence (January 21, Ms 6.4, 6.3) were not predicted. Three of the eight predictions made were not fulfilled, one of which was announced to the public (a false alarm). Four of the remaining five predictions were acted on by local authorities and the public was notified 2.5 h to 4 days before the earthquakes, which caused no deaths. One earthquake (April 11, Ms 6.6) struck 30 min after the prediction was made but before action could be taken by the local authorities, and it caused nine deaths. These predictions were based on composite observations of precursory anomalies in seismicity, electromagnetic fields, and crustal deformation, which were in turn compiled over the past 30 years in a nationwide earthquake monitoring program. Examples of precursory anomalies include: (1) a clear seismicity pattern of “quiescence—intensification—main shock(s)” was observed for the April 6 earthquakes (Ms 6.3, 6.4), which was previously applied to the prediction of the well-known 1975 Haicheng earthquake in Laoning, China; (2) distinct decreases in b-values preceded the earthquakes on March 1 (Ms 6.0) and April 6 (Ms 6.3, 6.4); (3) anomalous variation of geomagnetic vertical component preceded the April 6 earthquakes (Ms 6.3, 6.4); (4) sudden decreases in borehole strain preceded 8 of the earthquakes.
Tectonic setting of the 1971 Sylmar and 1994 Northridge earthquakes in the San Fernando Valley, California
Authors: Tsutsumi Hiroyuki , Yeats Robert S.
Published: November 2022

The San Fernando Valley lies above the north-dipping 1971 Sylmar and south-dipping 1994 Northridge earthquake faults. To understand the tectonic setting of these two earthquakes, we mapped subsurface geology of the San Fernando Valley down to a depth of ∼3 km, using industry oil-well and seismic data. The 1994 Northridge earthquake did not rupture the surface, and the south-dipping aftershock zone terminated against the north-dipping 1971 aftershock zone at a depth of 5-8 km. However, the blind Northridge fault has a near surface geologic expression; fault-propagation folding related to the Northridge fault has preserved a thick forelimb sequence of Plio-Pleistocene Saugus Formation in the Sylmar basin and Merrick syncline, which are located on the hanging wall side of north-dipping reverse faults. The north-dipping Mission Hills, Verdugo, and Northridge Hills reverse faults are interpreted to be potential seismic sources because fault-propagation folds above these faults have tectonic geomorphic expression. These north-dipping reverse faults were initiated during the deposition of the Saugus Formation between 2.3 and 0.5 Ma. and have minimum dip-slip rates of 0.35 to 1.1 mm/yr based on the oldest possible age of the initiation of faulting. The Northridge Hills and Mission Hills faults are interpreted to merge at depth and are located at the updip extension of the 1971 aftershock zone, even though these faults did not rupture during the 1971 earthquake. Surface breaks appeared north of these faults mostly along north-dipping bedding planes and are interpreted as secondary features related to flexural-slip folding rather than a direct extension of the 1971 seismogenic fault. Surface and subsurface geology, together with seismological data of the 1971 and 1994 earthquakes, suggests that the north- and south-dipping deformation zones in the San Fernando Valley are divided into multiple segments separated by northeast-trending structural discontinuities.
Estimating prehistoric earthquake magnitude from point measurements of surface rupture
Authors: Hemphill-Haley Mark A. , Weldon Ray J.
Published: November 2022

We have developed a method for estimating the magnitude of prehistoric earthquakes using displacement data that usually can be collected from paleoseismic investigations. This method is necessary because essentially all current magnitude estimates for prehistoric events rely on determining the total length of coseismic surface rupture, which is rarely measurable, or rely on segmentation scenarios, for which uncertainties cannot be quantified. Although surface rupture length is a better predictor of magnitude than displacement for historic earthquakes, paleoseismic investigations are better at providing measurements of the amount of displacement at a site along a fault. The key to our method is to incorporate the variability in displacement observed in 14 modern events, which allows a formal uncertainty in magnitude to be assigned to prehistoric ruptures. We show how multiple measurements along a preserved fraction of a rupture can be combined to reduce the uncertainty in the estimate of magnitude. Our analysis shows that uncertainty asymptotically approaches the natural variability of ruptures, so 5 to 10 displacement measurements are sufficient to characterize paleomagnitude. We conclude that sampling of scarps with lengths of even 10% of the original rupture can provide magnitude values that reasonably estimate the earthquake. Tests of the method, using randomly sampled data from the 1992 Mw 7.3 Landers and 1954 Ms 6.8 Dixie Valley earthquakes, provide close approximations of the actual magnitudes.
Analisis proximal y contenido de hierro y calcio de Nostoc sphaericum “cushuro” deshidratado procedente de la laguna de Conococha, Catac – Huaraz
Authors: Alegre Coveñas Raúl Eduardo , Ojeda Pereda Margarita Clara , Acuña Leiva Alex Yony
Published: November 2022

El presente trabajo de investigación, es de diseño no experimental descriptivo simple, se realizó con el propósito de determinar el análisis proximal de proteínas, hierro y calcio en muestra seca de Nostoc sphaericum “cushuro” procedente de la laguna de Conococha, Distrito de Catac, Provincia de Huaraz, Departamento de Ancash. El análisis de resultados se realizó en el programa Excel 2016, a través de los parámetros estadísticos descriptivos como promedio y desviación estándar. Para la determinación del análisis proximal en 100g de Nostoc sphaericum “cushuro” pulverizado, se utilizó el método Kjeldahl, encontrándose un 26.68 ± 0.01% de proteínas, 0.21 ± 0.03% de grasa, 5.77 ± 0.11% de fibra cruda, 11.23 ± 0.42% de humedad, 7.77 ± 0.01% de ceniza, para la determinación de hierro, se utilizó el método colorimétrico basado en reacciones con ortoferantrolina, encontrándose 15.72 ± 2.07 mg/100g de muestra seca y para el calcio se aplicó el método de complexometria por titulación con ácido etilendiamino tetraacético (EDTA), obteniendo como resultado 1224.4mg de Ca/100g de “cushuro” deshidratado. Se concluye que Nostoc sphaericum “cushuro” deshidratado es importante en la alimentación por poseer alto contenido de proteínas, hierro y calcio e indispensable para su uso con el tratamiento de la anemia, desnutrición y osteoporosis.
Responsabilidad social e investigación científica en una universidad privada de Lima, Perú
Authors: Charry Aysanoa Juan Marciano , Salinas Cruz María Ángela , Saberbein Muñoz Carlos , Prado Coronado Viviana
Published: November 2022

El artículo presenta los resultados de la investigación referida al cumplimiento de la responsabilidad social (RS) en a investigación científica (IC) en el país. Asume el paradigma Interpretativo, enfoque Cualitativo, diseño Hermenéutico. La muestra estuvo conformada por cinco estudiantes de Doctorado en una universidad privada de Lima, todos con grado de Magíster e involucrados en la IC. La técnica empleada fue la entrevista y el instrumento una guía de entrevista semi estructurada. El estudio reúne criterios de credibilidad, auditabilidad, transferencia y confirmabilidad de los datos, lo que determina la cientificidad del trabajo. Los resultados determinan que la RS, en términos generales, no se cumple cabalmente en el país, debido principalmente a los intereses capitalistas de las empresas e instituciones y a los fines de lucro, que no va más allá de los intereses económicos, por lo que la población se ve desprotegida en cuanto a su bienestar. La IC en el país como generadora de conocimiento y que busca la beneficiencia de la sociedad, no se está desarrollando a la luz de las necesidades de la sociedad actual; se da un desarrollo mínimo, evidenciándose una formación académica clásica, a ello se suma que los docentes investigadores que contribuyen a la formación de los estudiantes de posgrado no tienen el reconocimiento merecido y perciben remuneraciones bajas. La RS y la IC no se vinculan de manera provechosa ni se evidencia su importancia trascendental para la sociedad. Si bien se vislumbra una cierta relación en la ética, se publican muy poco los resultados de la investigación en revistas especializadas y mayormente estas publicaciones son de menor impacto. Respecto al papel de la universidad, se concluye que hay pasividad en el desarrollo de la IC con RS. La RS planificadas en proyectos sostenibles se reduce en una especie de asistencialismo a la población, a las gestiones específicas y no a la gestión general de contribuir al desarrollo humano de la sociedad. Urge promover planes sostenibles pero que sean realmente dirigidos a mejorar las condiciones de los pobladores.
Impacto Psicológico por la pandemia COVID-19 en los Profesionales de la Salud de la provincia de Cañete-Perú
Authors: Uribe-Hernández Yrene , Ruiz-Tejada José , Meneses-Claudio Brian , Gonzalez-Cordero Nahuel
Published: November 2022

El impacto psicológico es uno de los sucesos más importantes en la salud mental de la población, aunque en los profesionales de la salud, la situación pone en riesgo no solamente su salud mental, sino además de una mala calidad de atención a los pacientes, por lo que su objetivo de investigación es determinar el impacto psicológico por la pandemia COVID – 19 en profesionales de la salud. Es un estudio de enfoque cuantitativo, descriptivo, transversal y no experimental, con una población total de 192 profesionales de la salud, que respondieron una encuesta digital de datos sociodemográficos y el instrumento de recolección de datos Depression, Anxiety and Stress (DASS-21). En los resultados observamos que, 115(59,9%) de los profesionales de la salud tienen un impacto psicológico bajo, 16(8,3%) impacto psicológico medio y 61(31,8%) impacto psicológico alto. En conclusión, se debe tener en cuenta la promoción y prevención de la salud mental en los profesionales de la salud durante la atención en pacientes COVID – 19, puesto a que va a permitir en el profesional mantenerse adecuadamente estable y que pueda disminuir los cuadros de depresión, ansiedad y estrés.
NOTAS REPRODUCTIVAS DE COLACINTILLO COLINEGRO Lesbia victoriae (APODIFORMES: TROCHILIDAE) EN QUITO, ECUADOR
Authors: Narváez Izurieta Rafael Wilson
Published: November 2022

Resumen.- Realicé observaciones directas a siete nidadas de Lesbia victoriae entre 2016 a 2020 en el jardín de mi casa, en Quito. Hice seguimiento a tres nidos uno de los cuales tuvo cinco nidadas consecutivas. Las hembras después del cortejo, construyen los nidos, ponen dos huevos, los pichones nacen desnudos y abrieron los ojos a los 17 días, la hembra queda asentada en el nido entre los 13 - 15 días, incuba entre los 18 - 19 días. Los volantones están listos para volar a los 25 - 27 días y los volantones no presentan dimorfismo sexual. Este estudio presenta información actualizada de la biología reproductiva de Lesbia victoria en un ambiente urbano.

Palabras claves: anidación, ciudad, eclosión, incubación, nidos, pichones.
NESTING BIOLOGY OF AN ECUADORIAN ENDEMIC HUMMINGBIRD, THE ENDANGERED VIOLET-THROATED METALTAIL Metallura baroni
Authors: Carrasco Ugalde Agustín , Molina Paúl , Pacheco Daniel , Tinoco Boris
Published: November 2022

Violet-throated Metaltail Metallura baroni is a threatened hummingbird species, endemic to the Andes of southern Ecuador. Details about the reproductive biology of this species are largely unknown. In this manuscript, we describe the nest, eggs, and nestlings"™ development based on nine nests found along with the Cuenca-Molleturo-Naranjal road, in Cajas National Park, in 2019. We document a breeding period from March to May, which corresponds to the rainy season. All nests were found in roadside embankments, and were constructed with mosses, small twigs, rootlets, Polylepis sp. (Rosaceae) bark, and Puya sp. (Bromeliaceae) fibers. In all nests, we found two white oval eggs that were exclusively attended by a female across the breeding period. Hatching to fledging period lasted 28-32 days. Nesting at roadsides can be particularly risky due to a high probability of collision with vehicles; thus, an assessment of the breeding success of M. baroni on nests located at roadsides is a research priority for this species. The information provided here increases the knowledge about the natural history of M. baroni.
REGISTRO DE LA AGUJETA PIQUILARGA Limnodromus scolopaceus (SCOLOPACIDAE) DESPUÉS DE 89 AÑOS EN LA LAGUNA DE COLTA
Authors: Arteaga-Chávez William Andrés , Ocaña Edison , Hipo Rolando , Santander Tatiana
Published: November 2022

La Agujeta PiquilargaLimnodromus scolopaceus (Scolopacidae) se reproduce principalmente en el norte de América del Norte y migra hacia el sur de América del Norte y América Central durante el invierno boreal. En Ecuador son muy escasos los registros y se considera un visitante accidental. En esta nota presentamos el segundo registro de L. scolopaceus en la laguna de Colta, provincia de Chimborazo, luego de 89 años. Este registro representa la primera observación de campo en Colta, ya que el registro previo corresponde a un espécimen, y es la segunda vez que se observan varios individuos juntos en Ecuador. Los registros consecutivos en 2018-2020 en otros sitios del Ecuador continental podrían indicar que esta especie actualmente es un visitante más frecuente.
An Efficient and Fast Lightweight-Model with ShuffleNetv2 Based on YOLOv5 for Detection of Hardhat-Wearing
Authors: Cengil Emine , Çınar Ahmet , Yıldırım Muhammed
Published: November 2022

Traumatic brain injuries and collisions from falls and electric shocks are among the leading causes of construction deaths. Helmets play an important role in protecting working people from accidents. However, wearing a hard hat in real life is often not strictly enforced among those who try. Therefore, it is important to check this and ensure that a helmet is worn. Today, the use of artificial intelligence-based object recognition systems has become widespread due to the advantages it provides. In this article, a one-step object detection approach based on deep learning is proposed to detect helmet use and control helmet wearing status. The model is based on the YOLOv5 architecture. In the feature extraction step of the method, ShuffleNetv2, which is a lightweight model for a fast detector, is used. The presented model has been examined on the Hard Hat Workers dataset. The architecture provided a recall value of 0.942 precision 0.91 in the corresponding dataset. The obtained results showed that the recommended model is suitable for use on construction sites to check whether a helmet is fitted.
Anais 14 ° Congresso Internacional da Rede Unida - parte 4
Authors: Editores Saúde em Redes
Published: November 2022

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Anais 14° Congresso Internacional da Rede Unida - parte 6
Authors: Editores Saúde em Redes
Published: November 2022

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Anais 14 ° Congresso Internacional da Rede Unida - parte 12
Authors: Editores Saúde em Redes
Published: November 2022

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“Lugar de mulher é onde ela quiser” : caminhos cartográficos de mulheres na pesquisa em saúde
Authors: Teodoro Farias Quiteria Larissa , Cavalcante Ana Suelen Pedroza , Amaral Vitória Ferreira do , Alencar Olga Maria de , Barreto Marinho Mirna Neyara Alexandre de Sá , Vasconcelos Maristela Inês Osawa , Silva Maria Rocineide Ferreira da
Published: November 2022

Apresentamos nosso percurso cartográfico na pesquisa em saúde, no lugar de fala de mulheres de luta, que buscam espaço em terreno eminentemente masculino. Nosso objetivo é tecer reflexões a partir de nossas experiências em territórios de vida, na pesquisa em saúde e da análise crítica do mundo. A proposição é escapar dos procedimentos metodológicos tradicionais estabelecidos na ciência positivista. Para tanto, nos aventuramos no método cartográfico, que busca explorar as multiplicidades que integram nossas caminhadas. O local desse encontro, é o semiárido nordestino, e a adoção do termo encontro, parte da nossa história enquanto mulheres que vivenciam trajetórias acadêmicas, de origens diferentes. Nossa experiência nos faz refletir que o acesso a graduação e a pós-graduação é diferente não só quanto ao gênero, mas dentro do grupo de mulheres também há uma diferenciação econômica e racial. Apontamos, também que mesmo diante das dificuldades traçamos nosso percurso participando de coletivos que construíram as profissionais que somos hoje. Concluímos que nosso lugar é onde quisermos estar e que para vencer esse mundo de opressão só é possível a partir da sororidade, uma vez que integrar o mundo da ciência é também exercer um papel político, ético e social.
Clinical, epidemiological, and mycological features of patients with candidemia: Experience in two tertiary referral centers in Iran
Authors: Kord Mohammad , Salehi Mohammadreza , Hashemi Seyed Jamal , Abdollahi Alireza , Alijani Neda , Maleki Ayda , Mahmoudi Shahram , Ahmadikia Kazem , Parsameher Nasrin , Moradi Masoud , Abdorahimi Mahsa , Rezaie Sara , Hashemi Fesharaki Shirin Sadat , Abbasi Kiana , Alcazar-Fuoli Laura , Khodavaisy Sadegh
Published: November 2022

Background and Purpose: Candidemia is a major cause of morbidity and mortality among patients receiving immunosuppressive therapy and those hospitalized with serious underlying diseases. Here, we investigated the epidemiological, clinical, and mycological features of candidemia in Tehran, Iran.
Materials and Methods: A prospective observational study of all patients diagnosed with candidemia was performed at two referral teaching hospitals in Tehran, Iran, from February to December 2018. Demographic characteristics, underlying diseases, risk factors, clinical symptoms, and laboratory analyses of candidemic patients with positive culture were mined. Candida isolates were molecularly identified by sequencing of the internal transcribed spacer region (ITS1-5.8S-ITS2). The antifungal susceptibility testing for fluconazole, itraconazole, voriconazole, posaconazole, amphotericin B, caspofungin, micafungin, and anidulafunginagainst the isolates was performed using CLSI broth microdilution reference method (M27-A3).
Results: A total of 89 episodes were identified, with an incidence of 2.1 episodes/1000 admissions. The common underling disease were malignancy (46%), renal failure/dialysis (44%), and hypertension (40%). The overall crude mortality was 47%. C. albicans (44%) was the most frequent causative agent, followed by C. glabrata (21%), C. parapsilosis complex (15%), C. tropicalis (11%), and C. lusitaniae (3.5%). All the isolates were susceptible to amphotericin B. The activity of all four azoles was low against non-albicans Candida species, especially C. tropicalis.
Conclusion: The increase in non-albicans Candida species with reduced susceptibility to antifungal drugs might be alarming in high-risk patients. Therefore, accurate knowledge of predisposing factors and epidemiological patterns in candidemia are effective steps for managing and decreasing the mortality rate in candidemia.
Candida auris and COVID-19: A health threatening combination
Authors: Khojasteh Shaghayegh , Jafarzdeh Jalal , Hosseini Seyed Abdollah , Haghani Iman , Turki Habibollah , Aghaei Gharehbolagh Sanaz , Abastabar Mahdi , Mahmoudi Shahram
Published: November 2022

Since its first emergence in December 2019, due to its fast distribution throughout the world, SARS-COV-2 become a global concern. With the extremely increased number of hospitalized patients, this situation provided a potential basis for the transmission of nosocomial infections. Candida auris is a multidrug-resistant pathogen with improved transmission dynamics and resistance traits. During the worldwide spread of COVID-19, cases or outbreaks of C. auris colonization or infection have been reported. Resistance to antifungal drugs has been observed in the causative agents of the majority of such cases. The focus in this review is on COVID-19-associated C. auris infections (case studies/outbreaks) and the pandemic's potential effect on antifungal drug resistance.
Candida species isolated from clinical samples in a tertiary hospital in Honduras: Where is Candida auris?
Authors: Ortiz Bryan , Aguilar Kateryn , Galindo Celeste , Molina Lizzy , Fontecha Gustavo
Published: November 2022

Background and Purpose: Infections by emerging and multiresistant Candida species are becoming more frequent throughout the world. This study aimed to describe Candida species in different wards of a tertiary hospital in Honduras.
Materials and Methods: The prevalence of species within the C. albicans complex was estimated using a molecular approach, and C. auris was investigated using a yeast poolbased DNA extraction method. In total, 328 yeast isolates were identified using phenotypic approaches. For the identification of species within the albicans complex, a molecular approach based on the size polymorphisms of the hpw1 gene was used. In addition, a technique was optimized based on DNA extraction in pools for the rapid identification of C. auris.
Results: A total of 11 species of Candida were identified in the hospital wards. C. albicans showed the highest number of isolates (52.4%). Within the C. albicans complex, C. albicans sensu stricto was the most common, followed by C. dubliniensis. However, C. auris was not found.
Conclusion: Reports on the distribution of Candida species in Honduras are limited; accordingly, the data from this study are of importance for a better understanding of their epidemiology. Moreover, a simple method was offered for the detection of C. auris that could help in its detection in low-resource settings.
A rare case of a nasal cavity fungus ball due to Aspergillus niger
Authors: Köroğlu Emine Nur , Evirgen Şehrazat , Abed Ahmed Badri , Korcan Safiye Elif , Efeoğlu Koca Cansu Gül
Published: November 2022

Background and Purpose: Fungus Ball (FB) is a non-invasive fungal infection caused mainly by Aspergillus species. It can occur after root canal treatments are applied to the teeth adjacent to the maxillary sinus. These balls are commonly seen in the paranasal sinuses and rarely observed in the nasal cavity. This report attempted in to highlight such a rare case of fungal infection which requires accurate observation. Moreover, it highlights the importance of careful microbiological and histopathological examinations that were combined with imaging and can lead to a definitive diagnosis.
Case report: Herein, we report a rare case of a FB found in the vicinity of the nasal cavity of a 73-year-old male patient. Microbiological examination supported by radiographic and histopathological results indicated that the FB is due to Aspergillus niger. Excised surgery was done to the FB area, and the patient was referred to the postoperation room with the proper recommendations. After the wound healed, the total denture was performed as requested by the patient, and his overall oral health was improved.
Conclusion: In this article, we report the first case of a rare FB in the vicinity of the nasal cavity of a 73-year-old male patient. The appropriate investigation is an essential step in the diagnostic process for these infections and requires effective communication and collaboration.