bluuebunny/crossref_metadata_2025 huggingface dataset:
Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China
Authors: Xing Xiu-Ya , Wang Xin-Yi , Fang Xi , Xu Jing-Qiao , Chen Ye-Ji , Xu Wei , Wang Hua-Dong , Liu Zhi-Rong , Tao Sha-Sha
Published: October 2022

Objective

To investigate the status of glycemic control and analyze its influencing factors in patients with type 2 diabetes (T2D) in Anhui, China.

Methods

1,715 T2D patients aged 18–75 years old were selected from 4 counties or districts in Anhui Province in 2018, using a convenience sampling method. All patients have undergone a questionnaire survey, physical examination, and a glycosylated hemoglobin (HbA1c) test. According to the 2022 American Diabetes Association criteria, HbA1c was used to evaluate the glycemic control status of patients, and HbA1c < 7.0% was defined as good glycemic control. The influencing factors of glycemic control were analyzed by multivariate unconditional logistic regression.

Results

The prevalence of good glycemic control among people with T2D in the Anhui Province was low (22.97%). On univariate analysis, gender, education level, occupation, region, smoking, drinking, waist circumference and disease duration (all P < 0.05) were significantly associated with glycemic control. The factors associated with pool glycemic control were female gender [OR = 0.67, 95%CI (0.52, 0.86), P = 0.001], higher level of education [OR = 0.47, 95%CI (0.27, 0.83), P = 0.001], living in rural areas [OR = 1.77, 95%CI (1.39, 2.26), P < 0.001], central obesity [OR = 1.58, 95%CI (1.19, 2.09), P = 0.001] and longer duration of disease [OR = 2.66, 95%CI (1.91, 3.69), P < 0.001].

Conclusions

The prevalence of good glycemic control in people with T2D in Anhui Province was relatively low, and gender, region, education level, central obesity and course of the disease were influencing factors. The publicity and education on the importance of glycemic control should be further strengthened in T2D patients, and targeted intervention measures should be carried out for risk groups.
COVID-19 vaccination hesitancy and willingness among pregnant women in Italy
Authors: Miraglia del Giudice Grazia , Folcarelli Lucio , Napoli Annalisa , Corea Francesco , Angelillo Italo Francesco ,   The Collaborative Working Group
Published: October 2022

Background

Pregnant women, especially those with comorbidities, compared to those non-pregnant, have higher risk of developing a severe form of COVID-19. However, COVID-19 vaccine uptake is very low among them.

Methods

An anonymous questionnaire was administered to randomly selected women 18 years of age that were currently pregnant or had just given birth between September 2021 and May 2022 in the geographic area of Naples. Vaccine hesitancy was assessed using the vaccine hesitancy scale (VHS).

Results

A total of 385 women participated. Women who had not been infected by SARS-CoV-2 and who needed information about vaccination against COVID-19 had a higher perceived risk of being infected with SARS-CoV-2. More than half (54.3%) of the women were very afraid of the potential side effects of the COVID-19 vaccination on the fetus. There was higher concern of the side effects of the vaccine on the fetus among those who did not have a graduate degree, those with high-risk pregnancy, those who had not been infected by SARS-CoV-2, those who were more concerned that they could be infected by SARS-CoV-2, those who did not know that this vaccination was recommended for them, and those trusting mass media/internet/social networks for information. Only 21.3% were vaccinated when pregnant, mostly women with a university degree, those who had been infected by SARS-CoV-2 before pregnancy, those who did not need information, and those who acquired information about the vaccination from gynecologists. Almost three-quarters (71.9%) were willing to receive the vaccination and those more likely were those with a university degree, those who have had at least one relative/cohabitant partner/friend who had been infected by SARS-CoV-2, those who were more concerned that they could be infected by SARS-CoV-2, and those who were not extremely concerned of the side effects of the vaccine on the fetus. A total of 86.4% were highly hesitant. Highly hesitant were respondents who did not get a graduate degree, those less concerned that they could be infected by SARS-CoV-2, and those trusting mass media/internet/social networks for information.

Conclusion

Public health efforts and education campaigns for pregnant women are needed for changing their perception patterns and for supporting gynecologists in promoting the uptake of this vaccination.
No-code robotic programming for agile production: A new markerless-approach for multimodal natural interaction in a human-robot collaboration context
Authors: Halim Jayanto , Eichler Paul , Krusche Sebastian , Bdiwi Mohamad , Ihlenfeldt Steffen
Published: October 2022

Industrial robots and cobots are widely deployed in most industrial sectors. However, robotic programming still needs a lot of time and effort in small batch sizes, and it demands specific expertise and special training, especially when various robotic platforms are required. Actual low-code or no-code robotic programming solutions are exorbitant and meager. This work proposes a novel approach for no-code robotic programming for end-users with adequate or no expertise in industrial robotic. The proposed method ensures intuitive and fast robotic programming by utilizing a finite state machine with three layers of natural interactions based on hand gesture, finger gesture, and voice recognition. The implemented system combines intelligent computer vision and voice control capabilities. Using a vision system, the human could transfer spatial information of a 3D point, lines, and trajectories using hand and finger gestures. The voice recognition system will assist the user in parametrizing robot parameters and interacting with the robot’s state machine. Furthermore, the proposed method will be validated and compared with state-of-the-art “Hand-Guiding” cobot devices within real-world experiments. The results obtained are auspicious, and indicate the capability of this novel approach for real-world deployment in an industrial context.
Revisiting the measure of development: A critique of sustainametrics
Authors: Okui Go , Takeda Shutaro
Published: October 2022

For sustainametrics to gain a firm ground as an effective concept, the meaning of development shall be revisited first without depending on any statistical measurement. The word “development” originally meant the act of disclosure or opening a cover to disclose what is inside. Martin Heidegger (1889–1976) analyzed the significance of alētheuein, or “to bring the world out of its hidden and covered state and into ours,” and explicates that the alētheia under the condition of modern technology is dominated by a mode of revealing that is destructive to the earthly beings. Here, the danger inherent in the essence of technology, i.e., enframing [Ge-stell], renders human beings incapable of encountering the essence of beings as they are challenged and demanded to frame everything they encounter, including themselves, as mere variables. In contrast to Heidegger's thinking as releasement [Gelassenheit], Hannah Arendt's (1906–1975) conception of disclosure is closely tied to action. Following Heidegger's and Arendt's threads of thought, the authors conclude that any measures of development must be fundamentally grounded in disclosure through speech and action in the public realm. In this respect, the experts on the sustainametrics shall inspire fellow citizens to join the discourse by taking the risk of acting and speaking in public, disclosing who they are and what it is really meant for us. The course of development must ultimately be grounded in such an act of disclosure, only through which we may find something worth sustaining in our future development, and sustainametrics is no exception.
We don't want your water: Broadening community understandings of and engagement in flood risk and mitigation
Authors: Skilton Liz , Osland Anna C. , Willis Emma , Habib Emad H. , Barnes Stephen R. , ElSaadani Mohamed , Miles Brian , Do Trung Quang
Published: October 2022

Many communities across the USA and globally lack full understanding of the flood risk that may adversely impact them. This information deficit can lead to increased risk of flooding and a lack of engagement in mitigation efforts. Climatic changes, development, and other factors have expedited changes to flood risk. Due to these changes, communities will have an increased need to communicate with a variety of stakeholders about flood risk and mitigation. Lafayette Parish, Louisiana, USA, having recently experienced a major flood event (the 2016 Louisiana Floods), is representative of other communities experiencing changes to flood impacts. Using focus groups, this study delves into better understanding the disconnect between individual and community perceptions of flood risks, and how emerging hydroinformatics tools can bridge these gaps. Using qualitative analysis, this study evaluated the resources individuals use to learn about flooding, how definitions of community impact flood mitigation efforts, how individuals define flooding and its causes, and where gaps in knowledge exist about flood mitigation efforts. This research demonstrates that individuals conceive of flooding in relationship to themselves and their immediate circle first. The study revealed division within the community in how individuals think about the causes of flooding and the potential solutions for reducing flood risk. Based on these results, we argue that helping individuals reconceive how they think about flooding may help them better appreciate the flood mitigation efforts needed at individual, community, and regional levels. Additionally, we suggest that reducing gaps in knowledge about mitigation strategies and broadening how individuals conceive of their community may deepen their understanding of flood impacts and what their community can do to address potential challenges.
Perioperative changes in cardiac biomarkers in juvenile cats during neutering
Authors: Konishi Keisuke , Sakamoto Mei , Satake Chikara , Isaka Mitsuhiro , Okazaki Seiji , Kono Shota , Nakamura Takayuki , Tashiro Hideki , Ushigusa Takahiro
Published: October 2022

Perioperative myocardial injury (PMI) is commonly caused by myocardial ischemia that develops during or after non-cardiac surgery. It occurs in 17.9% of human patients after non-cardiac surgery due to elevated high-sensitive perioperation cardiac troponin. However, PMI has not been demonstrated in cats. To investigate its occurrence, this study aimed to analyze the perioperative changes in cardiac biomarkers and clinical data, including measurement of vital signs, echocardiography, blood pressure, electrocardiogram, X-ray, and anesthetic profile, in 30 juvenile cats under neutering surgery. All cats had increased high-sensitive cardiac troponin I (hs-cTnI) postsurgery compared with presurgery. In particular, 48% of cats (14/29) showed elevated hs-cTnI over a reference range after surgery. In all groups, hs-cTnI and systolic arterial blood pressure (SAP) were significantly higher at 0 h and 18 h postoperation than at preoperation. A significant positive correlation was found between hs-cTnI and SAP at 18 h postoperation. Atrial natriuretic peptides, heart rate, and left ventricular wall thickness were markedly higher at 0 h postoperation than at preoperation; however, respiratory rate and body temperature were significantly lower at 0 h postoperation than at preoperation. Anesthetic time and hs-cTnI were significantly higher at 18 h postoperation in females than in males. Significant positive correlations were observed between hs-cTnI and anesthetic time at 18 h postoperation in females. These results indicate that postoperative hs-cTnI level can greatly increase in juvenile cats and hs-cTnI measurement at perioperation is potentially beneficial for early detection and evaluation of the presence of PMI.
Congenital malformations in brachycephalic dogs: A retrospective study
Authors: Estevam Marina Vilela , Beretta Samara , Smargiassi Nathalia F. , Apparício Maricy , Toniollo Gilson Helio , Pereira Gener T.
Published: October 2022

The popularity of brachycephalic dogs has increased in recent years due to their docile temperament and peculiar features. The historical inbreeding and consequent lack of genetic diversity involved in the development of these breeds led to an increase in the manifestation of deleterious genes that may lead to malformations. In addition, there are serious health issues intrinsic to the conformation, mainly attributed to these extreme characteristics. Therefore, this retrospective study aimed to observe the frequency of malformations in brachycephalic dogs compared to the pure and mixed breeds (MB). The medical records of pregnant bitches admitted at the Service of Obstetrics and Animal Reproduction (SORA) from January 2017 to December 2021 were retrieved from the hospital's computer system and analyzed one by one. Seven hundred sixty-eight neonates born from 168 litters were included in this study. Of these litters, 72.6% (122/168) were brachycephalic. Malformations were found in 52 puppies, with an incidence of 6.77% (52/768). Of the 32 litters that produced malformed puppies, 28 were brachycephalic (87.5%). In total, 23 types of malformations were registered, the most common being cleft palate (1.30%) and anasarca (1.17%). Ten of the puppies (10/52; 19.23%) presented two or more associated malformations. Bitches above 7 years were more prone to present malformed puppies in their litters. Brachycephalic breeds were 3.03 times more likely to present malformed neonates when compared to other breeds; the odds ratio increased to 5.07 when modern brachycephalic was compared to ancestral brachycephalic. Regarding the mode of delivery, elective cesarean sections accounted for 66.6% of births while 19.64% were eutocic vaginal deliveries, and 13.69% were dystocic. The presence of malformed puppies in a litter causes suffering for the owner, the bitch and for the puppy itself, therefore, the veterinarian plays a key role in this scenario. Knowledge about congenital abnormalities, their causes, diagnosis, and approach is essential to reduce the incidence of malformations and improve the quality of life of these animals.
Diet of the Exotic Mosquitofish, Gambusia holbrooki, in an Australian Lake and Potential for Competition with Indigenous Fish Species
Authors:   Centre for Catchment and In-Stream Research Griffith Uniue,·sity, Nathan Queensland 4111, Australia, ARTHINGTON A.H. , MARSHALL C.J.
Published: October 2022

The exotic mosquitofish, Gambusia holbmoki Girard, has become established in fresh­water systems on sand islands of high conservation significance off the coast of southeast­ern Queensland, Australia. These freshwater systems support indigenous fish species with very restricted distributions and the mosquitofish has been listed as a threat to at least three rare species. This paper records the diet of G. holbrooki in an oligotrophic dune lake and explores the potential for competition for food between the mosquitofish, the Ornate Rainbowfish, Rhadinocenlnts ornatus (Melanotaeniidae), and the Firetail Gudgeon, H.ypseleotris galii (Eleotrididae). There was a high degree of similarity in mean population diets of R. ornatus and G. holbrooki (overlap index=0.83), moderate dietary overlap be­tween G. holbrooki and H. galii (overlap index=0.49) and low dietary overlap between R. omalu.s and H. galii (overlap index=0.18). In some months, the mosquitofish switched to feeding on aquatic invertebrates normally consumed by gudgeons, and levels of dietary overlap between these species increased markedly. The capacity of G. holbrooki to feed opportunistically on a wide variety of aquatic prey, confirmed again in this study, could ex­ert a significant pressure on small populations of both indigenous fishes. Of the two spe­cies studied here, the restricted Ornate Rainbowfish appears to be particularly vulnerable to the effects of dietary interactions with the mosquitofish.
A Preliminary Study on Nile Tilapia (Oreochromis niloticus) Polyculture with Common Carp (Cyprinus carpio) Fed with Duckweed (Spirodela) in Nepal
Authors: SHRESTHA M.K. , BHUJEL R.C.
Published: October 2022

Mixed-sex Nile tilapia (Oreochromis niloticus) and common carp (Cyprinus carpio) were cultured in four cement ponds of 72 m2 at 1:1 ratio with a stocking density of 1 fish· m·2 during summer in subtropical Nepal. Fish were fed with locally collected duckweed (Spirodela sp.) during 108 days of experimental period. Nile tilapia grew from 39.6±3.7 g at stocking to 145±5.2 g at harvesting with a survival rate of 90±4 %. Common carp grew from an initial 2.8±0.G g to final 63.2±2.4 g with 97±1 % survival rate. The ex­trapolated annual yield of stocked fish ranger.! from 2.3 - 2.9 t•ha·1 with a mean of 2.5 ±0.1 t·ha·1. Tilapia offsprings produced during the experimental period was 1690:±261 fish per pond with an average size of 7.2±1.6 g. Weight of tilapia recruits obtained was two times more than that of the net yield of originally stocked fish. The common carp did not control tilapia recruitments.
Virus Isolation from Epizootic Ulcerative Syndrome-Diseased Fishes
Authors: KANCHANAKHAN S.
Published: October 2022

Epizootic Ulcerative Syndrome (EUS) is a seasonal and widely spread ulcerative condition of fresh and brackishwater fishes in Asia caused by a complex of etiological agents. Viral agents have been found to be associated with EUS, but their role in the complex etiology still has to be identified. Further virological examinations were, therefore, conducted in this study. Twenty viral isolations were achieved from three epizootics in Thai­land. In the 1993-1994 epizootic, nine rhabdoviruses were successfully isolated from EUS snakehead (Channa striata) and three-spot gourami (Trichogaster trichopterus). Another nine rhabdoviruses were also isolated from 11 tissue extracts from affected snakeheads col­lected in the 1995-1996 outbreak. Two other viral isolates were obtained from affected gi­ant gourami (Osphronemus goummy) and climbing perch (Anabas testudineus) in the 1996- 1997 outbreak. These viruses were isolated only from samples collected during the early period of the outbreaks. The tissue samples collected from moribund fish, processed and inoculated on to cell culture within a few days gave the best virus isolation results. Virus isolation from the samples collected after the early period of the EDS from Thailand and Pakistan gave no cytopathic effect on the host cells. In this study, BF-2 cells seemed to be the best cell line for viral isolation followed by SSN-1 and HCK lines, while no virus could be obtained using the EPC and BB lines. Th£: results of this study suggest that the vi­ruses, especially 1;habdovirus, are readily isolated from diseased fishes during the early period of an outbreak, and that they may have a significant role in a complex of etiological agents of EUS.
Establishment of Cell Lines from Catfish (Clarias batrachus) and Snakeheads (Ophicephalus striatus)
Authors: LIO-PO G.D.
Published: October 2022

Primary cell cultures from catfish (Clarias batrachus) and snakeheads (Ophicephalus striatus) were prepared from whole fry and fingerling organ tissues of the brain, fins, gonad, heart, kidney, liver, skin and spleen. Four methods were tried: method A wherein explants were placed onto the surface of 25-cm2 Primaria flasks (Falcon), allowed to attach for an hour before addition of Leibovitz medium (L-15) supplemented with 15% fetal bovine serum (FBS)(Ll5-15); Method B wherein explants were inoculated into 25-cm2 Primaria flasks (Falcon) already containing L15-15; Method C which required forcing minced organ sections through a stainless steel sieve with the aid of a syringe plunger into a petri dish containing LI5-15 medium; and Method D wherein immersed sections of minced tissues to 0.5% trypsin-EDTA slowly agitated using a magnetic stirrer for one hour at 25 °C. Method B was most effective in the establishment of cell cultures from both fish species. Passage numbers of the cells are to date catfish gonad (CFG) P-56, catfish heart (CFH) P-51, catfish kidney (CFK) P-7, catfish liver (CFL) P-8, catfish spleen (CFS) P-54, snakehead gonad (SHG) P-26, snakehead heart (SHH) P-22, snakehead kidney (SHK) P-19, snakehead liver (SHL) P-49 and snakehead spleen (SHS) P-76. Attempts to derive primary cell cultures from organ tissues of the brain, fins, skin and whole fry were unsuccessful. Established cells were fibroblastic. The cells grew rapidly and became confluent 24 h after seeding at 20 and 25 °C. Both SHS and CFS were susceptible to a virus iso­lated from EUS-affected fish in the Philippines. The cells were best maintained at 20 °C and stored in liquid nitrogen or -70 °C.
Comparative Study of Experimental Mycobacteriosis Between Snakehead Fish (Chana striata) and Frog (Rana tigrina)
Authors: PHANWICHIEN K.
Published: October 2022

In many of the culture areas in Thailand, snakehead fish suffer mortality from septicemic mycobacterium infections (Chinabut et. al., 1990). The contaminated drainage from fish farms may spread into the environment and potentially cause problems to frog hatcheries and growout farms. A total of 80 fish and 160 frogs were intramuscularly injected with a pure cultured virulent strain of M. marinum, isolated from the kidney of a diseased snakehead fish with clinical signs of mycobacteriosis. The inoculated animals were observed daily for the appearance of clinical signs of infection and were sacrificed routinely for the pathological study. After 15 days of injection, the infected fish showed emaciation, lack of coordination, erosion of fins, scale loss and severe ulceration, whereas the infected frogs did not ·show any gross pathological lesions throughout the experiment. Gray-white miliary tubercles were observed in the spleen, kidney and liver of the infected fish whereas these tubercles were never found in any organs of infected frogs. Histologically, the granulomatous inflammation was observed both in fish and frogs. Granulomas found in the visceral organs, dermis and injected areas of fish and in the injected areas of frogs revealed the composition of epithelioid and phagocytic cells surrounded by whorls of fibroblastic cells. Central caseous necrosis was observed only in fish granulomas. Two different cell types were noticed in frog skin in the early period of the experiment. The dark elongated nuclear cells resembling mammalian Langerhans cells were observed in the suprahasal epidermis, and the stellate shaped dendritic cells were observed both in the dermis and hypodermis. Both cell types are reported with reference to delayed-hypersensitivity in humans.
Impact of Oxytetracycline on Rana tigrina
Authors: SOMSIRl T.
Published: October 2022

Oxytetracyeline (OTC) is a popular antimicrobial agent for the prevention and treatment of bacterial diseases of cultured frogs (&ma tigrina) in Thailand. Doses used are similar to those recommended for fish. Tadpoles ages 5, 15 and 25 days were fed with 1, 3, 5 gram OTC/kilogram of feed, or bathed with OTC at a concentration of 10, 20 or 30 ppm for five days. Residues of the drug were eliminated from 5 and 15 day old tadpoles three days post treatment, but 25 day old tadpoles needed four days to eliminate OTC. Frogs weighing 120 g were treated once with OTC by natural or forced feeding at doses of 1, 3 or 5 g/kg of feed or were injected with OTC at 10 or 50 mg/kg body weight, OTC were measured m the serum and various internal organs. Elimination of OTC from the tissues of frogs treated by injection waa longer than that of OTC fed frogs. Histological studies revealed that tadpoles and frogs treated with OTC showed microvesicular fatty change and necrosis in the liver and kidneys. Mucosa of the intestinal tract in the injected group exhibited focal hyaline degeneration. These results indicate that long term OTC treatment has .an effect on the histology of tadpoles and frogs.
Speaker Naming in Arabic TV Programs
Authors: Bellagha Mohamed Lazhar , Zrigui Mounir
Published: October 2022

Automatic speaker identification is the problem of identifying speakers by their real identities. Previous approaches use textual information as a source of naming, try to associate names to neighbouring speaker segments using linguistic rules. However, these approaches have a few limitations that hinder their application on spoken text. Deep learning approaches for natural language processing have recently reached state-of-the-art results. However, deep learning requires a lot of annotated data which is difficult to obtain in the case of speaker identification task. In this paper, we present two contributions towards integrating deep learning for identifying speakers in news broadcasts: first we realise a dataset in which the names of mentioned speakers are related to the previous, next, current or other speaker turns. Moreover, we present our approach to solve the problem of speaker identification using information obtained from the transcription. We use a Long-term Recurrent Convolutional Network for name assignment and integer linear programming for name propagation into the different segments. We evaluate our model on both assignment and propagation tasks on the test part of the Arabic multi-genre broadcast dataset which consists of 17 TV programs from Aljazeera. The performance is analysed using the evaluation metrics, such as Estimated Global Error Rate (EGER) and Diarization Error Rate (DER). The outcome of the proposed method ensures better performance by achieving the lower EGER of 32.3% and DER of 8.3%.
Hybrid User Acceptance Test Procedure to Improve the Software Quality
Authors: Sowri Raja Pillai Natarajan , Rani Hemamalini Ranganathan
Published: October 2022

Fast-growing software needs result in the rise of quality software in technical and time challenges in software development and the impact the cost and scarcity of resources addressed by the companies. Thus, this research focuses on optimal implementation of the User Acceptance Testing (UAT) and the process generation integration. The Software Development Life Cycle (SDLC) was adapted to develop software and introduce the UAT process right from the initial phase of the software development. Additionally, it is devised to maximise time reduction by implementing the client testing in all the three processes. A High Capability to Detect (HCD) procedure has been incorporated in the problem formulation that has optimally identified sensitive bugs. A Modified Reuse of Code (MRC) is proposed for a feasible time-saving solution. The proposed UAT will provide an optimal solution in the software testing phases implemented earlier than black-box testing. The proposed UAT has significantly better production time, development cost, and software quality in comparison to other traditional UATs. The study's findings were corroborated by the output data from the UAT cases. The UAT ensures the quality of the product in the early phase of the development and implementation of the projects. This will minimise the risk during and post-implementation of bugs and achieve the target audience’s needs.
Analysis of Video Steganography in Military Applications on Cloud
Authors: Ramamoorthy Umadevi , Loganathan Aruna
Published: October 2022

The analysis of secure video file transfer with military application for video steganography on cloud computing is essential role. Video steganography is the process of hiding the secret data which is presented in the video and it is based on the reversible and irreversible schemes. The reversible scheme has the capability to insert the secret data into a video and then recover the video without any failure of information when the secret data is extracted. Irreversible methods on video steganography often deal with sensitive information, making embedded payload an important concern in the design of these data hiding systems. In video steganography, irreversible contrast mapping is considered for extracting the secret data during the process of hiding the data. During this extraction process, high quality data hiding is carried in video steganography. The analysis consequences of the proposed method Video Steganography Cloud Security (VSCS) shows that the structure for secure communication and augments the confidentiality and security in cloud. This result of the proposed method shows the better security level.
Materias primas líticas y tecnología en la costa oeste del golfo San Matías y su interior inmediato (Provincia de Río Negro, Argentina). Un estudio comparativo
Authors: Alberti Jimena
Published: October 2022

En este trabajo se presentan los resultados de los primeros análisis de la muestra artefactual recuperada en contextos de superficie en el área Paredón de los Grabados (provincia de Río Negro, Argentina). Se estudiaron las materias primas y se relevaron distintos indicadores para dar cuenta de la variabilidad tecnológica del conjunto. A su vez, se realizó una breve comparación con los conjuntos de artefactos de la costa oeste del golfo San Matías, en la mencionada provincia. Los resultados indican que en el interior del continente los conjuntos presentan una mayor proporción de instrumentos, estadios de talla más avanzados, predominan los filos simples y fueron utilizadas principalmente rocas de calidad excelente y muy buena para la talla. La muestra general indicaría un equipamiento del espacio a través del abandono de instrumentos con potencial de uso, a diferencia de lo que sucede en la costa en donde esto se habría dado a través de los núcleos y en donde los conjuntos presentan mayor variabilidad respecto de la calidad de las rocas utilizadas, observándose también estadios iniciales de talla. Finalmente, no ha sido posible establecer, a partir del análisis lítico, una relación clara entre la costa y el interior.
Variational optimality condition in control of hyperbolic systems with boundary delay parameters
Authors: Arguchintsev Alexander , Poplevko Vasilisa , Sinitsyn Alexander
Published: October 2022

An optimal control problem of a first-order hyperbolic system is studied, in which a boundary condition at one of the ends is determined from a controlled system of ordinary differential equations with constant state lag. Control functions are bounded and measurable functions. The system of ordinary differential equations at the boundary is linear in state. However the matrix of coefficients depends on control functions. Therefore, the optimality condition of Pontryagin’s maximum principle type in this problem is a necessary, but not a sufficient optimality condition. In this paper, the problem is reduced to an optimal control problem of a special system of ordinary differential equations. The proposed approach is based on the use of an exact formula of the cost functional increment. The reduced problem can be solved using a wide range of effective methods used for optimization problems in systems of ordinary differential equations. Problems of this kind arise when modeling thermal separation processes, suppression of mechanical
vibrations in drilling, wave processes and population dynamics.
Parameters estimation of multi-sinusoidal signal in finite-time
Authors: Khac Tung Nguyen , Vlasov Sergey M. , Pyrkin Anton A.
Published: October 2022

The problems of identifying the frequency and parameters of multi-sinusoidal signals with constant parameters are considered in finite time. The signal is represented as the output of a linear generator, where the parameters of the sinusoidal signal (amplitude, phase, and frequency) are unknown. The main idea is to apply the Jordan waveform and lag to parameterize the signal and obtain a linear regression model. Unknown parameters are estimated using DREM method. The performance of algorithms considered in the article is illustrated by computer modeling. Our main contribution is to propose a new approach for parameterization of multisinusoidal signals and finite time parameter estimation.
Análisis de la sentencia de unificación del 29 de enero de 2020 de la Sección Tercera del Consejo de Estado que estableció los parámetros de la caducidad en los delitos de lesa humanidad y crímenes de guerra
Authors: Cortés Fajardo María Fernanda , Céspedes Cardona Natalia
Published: October 2022

En el presente artículo se estudia la sentencia de unificación del 29 de enero de 2020 de la Sección Tercera del Consejo de Estado, en la cual se establecieron los parámetros para el cómputo de la caducidad en el medio de control de reparación directa, cuando el daño es causado por delitos de lesa humanidad y crímenes de guerra cometidos por agentes del Estado, reglas que, como se determinará, desconocen la jurisprudencia de la Corte Interamericana de Derechos Humanos, sentencia Caso Órdenes Guerra y Otros vs. Chile. En el artículo se defenderá que adoptar las reglas jurisprudenciales dispuestas en la sentencia de unificación implica una grave violación al derecho de acceso a la administración de justicia para las víctimas de esta clase de delitos, el desconocimiento del principio pro homine e, inclusive, llegar a configurar una revictimización.
PENINGKATAN NILAI OVERALL EQUIPMENT EFFECTIVENESS MESIN STONE CRUSHER DENGAN MENGGUNAKAN PENDEKATAN TOTAL PRODUCTIVE MAINTENANCE (STUDI KASUS PT. BRANTAS ABIPRAYA)
Authors: Shafitri Diva Odilia , Larasati Aisyah , Hajji Apif Miptahul
Published: October 2022

Mesin stone crusher digunakan untuk memproduksi agregat, yang menjadi salah satu bahan utama dalam pembuatan beton. Permasalahan yang saat ini sedang dihadapi perusahaan Abipraya Beton adalah loss time mesin yang besar pada mesin stone crusher dan belum dapat memenuhi kuantitas dan kualitas yang diharapkan oleh perusahaan. Permasalahan tersebut menjadi fokus penelitian dalam meningkatkan efektivitas mesin stone crusher dengan pendekatan Total Productive Maintenance (TPM). Langkah yang dilakukan dalam menerapkan TPM adalah dengan menghitung nilai Overall Equipment Effectiveness (OEE) dan mengetahui faktor-faktor yang mempengaruhi nilai OEE dengan menghitung six big losses. Setelah itu, melakukan analisa dengan menggunakan diagram pareto, diagram fishbone, dan Failure Mode and Effect Analysis (FMEA), sehingga dapat diusulkan perbaikan dan strategi pemeliharaan. Hasil pengolahan data pada periode Agustus 2018-Agustus 2019, mesin stone crusher memiliki nilai OEE yang masih berada di bawah standar dunia yang dirumuskan oleh JIPM, yaitu sebesar 67%. Nilai tersebut menunjukkan bahwa ada ruang yang besar untuk dilakukannya peningkatan efektivitas. Faktor terbesar yang mempengaruhi rendahnya nilai OEE adalah idling and minor stoppages (52,55%), reduced speed (26,68%), dan equipment failure (16,61%). Rekomendasi perbaikan yang diusulkan adalah perusahaan dapat menyediakan check sheet untuk kegiatan pemeliharaan rutin pada mesin stone crusher, melakukan pengecekan stok cadangan untuk komponen dan bahan bakar genset, memberikan pelatihan secara berkala kepada pekerja untuk meningkatkan kemampuan dan keterampilannya dalam hal mengoperasikan dan memelihara mesin stone crusher, dan menghimbau seluruh karyawan untuk berperan aktif dalam menerapkan metode TPM. Dengan penerapan TPM dan rekomendasi perbaikan maka nilai OEE mesin stone crusher tahun 2021 diharapkan dapat meningkat menjadi 86%.
ANALISIS KAPABILITAS PROSES MESIN FILLING UNTUK PENGENDALIAN KUALITAS PADA PRODUK SIRUP OBAT BATUK DI INDUSTRI FARMASI
Authors: Mukhamad Arif
Published: October 2022

Abstrak

PT ABC adalah salah satu perusahaan swasta milik perseorangan yang bergerak dibidang industri farmasi. Salah satu produk obat yang di produksi adalah sirup obat batuk merk XYZ. Masalah yang terjadi dalam penelitian ini adalah adanya pemborosan produksi disebabkan oleh ketidakstabilan volume produk khususnya produksi sirup obat batuk XYZ. Penelitian ini bertujuan untuk menganalisa nilai kapabilitas proses yang dihasilkan dari mesin filling produksi sirup obat batuk terutama parameter volume dan mengetahui faktor-faktor penyebab terjadinya ketidaksesuaian dalam produk. Beberapa metode yang digunakan dalam penelitian ini antara lain peta kendali, kapabilitas proses dan Fishbone. Hasil penelitian ini menunjukan volume produk obat batuk sirup dari hasil filling sirup dari produksi obat batuk di industri farmasi didapatkan indeks Cp rata-rata sekitar 0.45 dan Cpk rata-rata 0.45. Sehingga dapat disimpulkan bahwa proses belum memiliki kapabilitas yang baik.

 

Kata Kunci:  Sirup obat batuk, proses, Cp, Cpk, Fishbone
ATTENUATION OF HEMODYNAMIC RESPONSES DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION: A COMPARATIVE STUDY BETWEEN ORAL GABAPENTIN AND ORAL CLONIDINE.
Authors: Khare Deepak , Anand Tanuja
Published: October 2022

Background and Aims: Various methods have been used to supress pressor response and tachycardia
during laryngoscopy and endotracheal intubation. We compared oral gabapentin and oral clonidine for
surgeries under general anaesthesia. After clearance from IEC, sixty patients receiving general anae Methods: sthesia were
divided into two groups, GROUP C and GROUP G. Group C received tablet Clonidine 200 µg. Group G received capsule
Gabapentin 700 mg. Data was analysed using Student-t test for normal distribution and Mann-Whitney U test when not
normally distributed. Qualitative data (n%) was compared using Chi-square test. Hemodynamic p Result: arameters rise on
laryngoscopy and 1 minute after endotracheal intubation in both the groups. Further hemodynamic parameters dropped below
baseline in both groups subsequently. But as compared to Group C, Group G has less rise in hemodynamic variables.
Conclusion: Gabapentin was more effective and better than clonidine in attenuating hemodynamic response to laryngoscopy
and endotracheal intubation overall
SIRENOMELIA, THE FETAL MERMAID - A RARE CASE REPORT
Authors: Preeti Preeti , Sarbhai Vinita , Dewangan Bhagyashree
Published: October 2022

Sirenomelia or mermaid syndrome is a rare congenital condition. Condition is characterised by fusion of
lower limbs to form one single lower limb and is associated with bilateral renal agenesis, severe
pulmonary hypoplasia, genitourinary abnormalities, anomalies of lumbosacral spine and pelvis, anorectal defect,
gastrointestinal anomalies, single umbilical artery. It affects 1 in 100,000 live births worldwide, with the male to female gender
ratio being 3:1. We report a case of sirenomelia type-III in a multigravida female reported to our hospital at term gestation. Her
medical history was unremarkable, no associated risk factors, no history of drug abuse. No family history of congenital
anomalies. Condition is fatal due to associated visceral anomalies. Prenatal diagnosis is difcult in late second and third
trimester as severe oligohydramnios limits the visualisation of anomalies. Early diagnosis in rst or early second trimester is
recommended when the normal amount of amniotic uid allow detailed sonographic scanning.
COMPARISON OF NTG VS DEXMEDETOMIDINE FOR CONTROL OF HAEMODYNAMIC RESPONSE IN PATIENTS DURING EMERGENCE FROM ANAESTHESIA AND EXTUBATION FOLLOWING LAPAROSCOPY
Authors: Ranjan Nikita , Vennel Jessy , Sathe Deepika , Gala Rajvee , Jain Gayatri
Published: October 2022

Endotracheal intubation as well as extubation are associated with various cardiovascular and airway
responses leading to increase in heart rate (tachycardia), hypertension (HTN), cardiac arrhythmias,
myocardial ischemia (MI), coughing, agitation, bronchospasm, increased bleeding, raised intracranial tension etc.
Pneumoperitoneum creation in laparoscopic surgeries, leads to adverse changes in various systems of human body including
cardiovascular, respiratory and acid base balance system. Various factors which leads to haemodynamic changes in patient
are release of catecholamine, carbon di-oxide absorption, vasopressin release and position of the patient. NTG generate NO
(Nitric oxide) which causes vasodilatation in vascular smooth muscle leading to decrease in blood pressure. It also relaxes the
respiratory tract smooth muscle and hence it is preferred by anaesthesiologist to prevent laryngospasm. Dexmedetomidine is
an 2-adrenoreceptor agonist used to facilitate the extubation after surgeries. Dexmedetomidine used in the intraoperative
period causes decrease in serum catecholamine levels by 90%, which in turn blunts the haemodynamic response to
laryngoscopy, tracheal intubation, pneumo-peritoneum and extubation. So we did the comparative study between IV
dexmedetomidine and IV NTG on hemodynamic response during extubation in laparoscopic surgeries. To study and compare
the effect of intravenous nitro-glycerine (NTG) with dexmedetomidine in patients undergoing laparoscopic surgery and during
recovery in terms of haemodynamic response during tracheal extubation, airway reexes during tracheal extubation by using
extubation quality score, sedation by using Ramsay Sedation Scale & side effects of drug. 60 patients of ASA grade 1 and 2
undergoing laparoscopic surgery were divided into two groups of thirty each. GROUP D (n=30) will receive Dexmedetomidine
infusion at the rate of 0.75 mics/kg over 10 minutes and GROUP N (n=30) will receive NTG infusion at the rate of 2 mics/kg over
10 minutes .patients were assessed on the basis of ramsay sedation scale , extubation quality scale and vas scale every 1, 3, 5,
10 and 15 minutes. When both the groups were compared it was found out there was statistically signicant difference in
dexmedetomidine group as compared to NTG in terms of decrease in HR , BP, SBP , DBP, MAP , extubation quality score ,
ramsay sedation scale, and VAS scale .there was no overall complication in both groups. In conclusion, the Dexmedetomidine
at a dose of 0.75µg/kg body weight as compared to NTG ( 2 µg/kg body weight )when administered as infusion over 10 minutes,
before tracheal extubation attenuates the airway reexes and hemodynamic responses effectively during emergence from
anaesthesia providing smooth extubation. It provide adequate sedation, maintaining patient's arousability and delay the need
for analgesia in the post-operative period.
KNOWLEDGE, ATTITUDE AND PRACTICE OF BREAST SELF-EXAMINATION AND BREAST CANCER AMONG FEMALE HEALTHCARE WORKERS IN SUPERCARE HOSPITAL: A PILOT STUDY
Authors: Idauraile Idauraile , Hrangkhawl Wilson , Lyngdoh Pynhunlin
Published: October 2022

Objective: Breast cancer is the leading cause of mortality and morbidity among the females in India. Breast Self-examination (BSE) can play a huge role in early detection and diagnosis thereby signicantly reduce morbidity, and prompt timely treatment. The main aim of the study was to access the Knowledge, attitude and practice of breast self-examination and cancer awareness among the female healthcare workers. Methodology: The cross-sectional pilot study was conducted in Supercare hospital, Shillong and 27 female workers responded to the questioner. The questioners were divided into three categories to access the Knowledge, attitude and practice of BSE and awareness of breast cancer. Results: 22.22% of the participants had very good knowledge of breast cancer and BSE, 74% had good knowledge and 3.7% had average knowledge. 40.51±4.9 is the mean and SD for the knowledge for breast cancer and self-breast awareness. 48% respondents average practice BSE and 11% good and 41% poor practice of BSE was observed. The female healthcare workers attitude towards BSE was overall good. Conclusion: Majority of the respondents are aware of breast cancer but very few practice breast self-examination. It is recommended to educate and train female health worker to act as peer educator who are agent of health care information to the community and the society at large
ELEMENTAL CONCENTRATION OF PACKAGED MEALS (BAKED AND EXTRUDED GOODS MADE USING COMPOSITE CEREAL-PULSE FLOUR) PROCURED AT DEBRE TABOR MARKETPLACES IN ETHIOPIA
Authors: Alemye G. Mekuannent , Rao A.D.P. , Narayana P.V. Lakshmi
Published: October 2022

The elemental analysis of packed food items which is collected in Debre Tabor markets, Ethiopia namely
Pasta, Macaroni, cookies, biscuit, wheat bread, white teff injera, Red teff injera, barley so, barleycorn and
maiz bread samples were carried out using EDX spectrometer. An X-ray beam was used to excite each sample and spectra were
recorded with a high-resolution Si(Li) detector. The data analysis was carried out by software. Trace elements P, K, Na, Cl, Mg,
Ca, Fe, Al and Zn were estimated, and elemental concentrations were determined. To get the exact results of the present study the
analysis repeats three times.
VALGUS INTERTROCHANTERIC OSTEOTOMY USING DYNAMIC HIP SCREW FOR NEGLECTED NON-UNION OF NECK OF FEMUR FRACTURE IN A MIDDLE AGED MALE-A CASE REPORT.
Authors: Belapurkar Kaustubh , Agrawal Pravin
Published: October 2022

Neck of femur fracture is a common orthopaedic problem. The management of the non union of the neck
of femur is challenging because of the biological and the mechanical factors at play. Osteosynthesis is
the modality of choice for the people aged 60 years or less while arthroplasty is the treatment offered for the older age group.
Numerous techniques have been described for the osteosynthesis of the non union of neck of femur. The main principle of all
these methods remains optimization of the biology and mechanics of the fracture to promote fracture union and delay the onset
of hip arthritis. Here we describe a case of a young middle aged male who due to ongoing COVID-19 pandemic and the
imposed lockdowns was not able to receive proper healthcare. He presented to us with 9 months duration of nonunion of right
neck of femur fracture. Radiographs were obtained which revealed a Pauwels type 3 fracture and a Sandhu class 2 nonunion.
MRI studies were done to ascertain the viability of the femoral head. After all the investigations, a decision was taken to attempt
head salvage using a Valgus intertrochanteric Osteotomy. Careful preoperative assessment and calculations were done to
accurately determine the osteotomy wedge, DHS pin insertion angle and the goal Pauwels angle. It was decided to correct the
Pauwels angle to 30° to reduce shear forces at the fracture site and achieve compression at the fracture site. After the surgical
procedure patient was followed up and the fracture as well the osteotomy site showed the signs of union at 24 weeks post
operative. Patient achieved excellent function in his hip. He was able to walk pain and limp free, he could squat, sit crosslegged and perform his day to day activites as well as his ground level activites. His post operative Harris Hip Score was
90.8(excellent) at 24 weeks follow up. We thus conclude that a carefully planned valgus intertrochanteric osteotomy is able to
achieve excellent outcomes in young patients with non union of neck of femur.
BONE MARROW PLASMACYTOSIS- REACTIVE OR MALIGNANT? A DIAGNOSTIC CHALLENGE TO A NOVICE PATHOLOGIST
Authors: Mishra Jyoti , Mittal Salony , Gupta Vatsala
Published: October 2022

Plasmacytosis can be due to both reactive causes as well as monoclonal proliferation. Reactive
plasmacytosis is seen in infections, malignancy, iron deciency, megaloblastic anemia, hemolytic
anemia , liver cirrhosis, Castleman's disease and streptokinase treatment. Plasmacytosis in elderly patient can be a diagnostic
confusion especially in absence of one or more of hypercalcemia, Renal insufciency, anemia and bone lesions (CRAB). We
encountered a similar case of elderly person whose nal diagnosis was made after thorough radiological and pathological
evaluation.