bluuebunny/crossref_metadata_2025 huggingface dataset:
Stimulating Methane Production from Poultry Manure Digest with Sewage Sludge and Organic Waste by Thermal Pretreatment and Adding Iron or Sodium Hydroxide
Authors: Jasińska Anna , Grosser Anna , Meers Erik , Piłyp Dagmara
Published: May 2024

The European Union’s energy policy favors increasing the share of renewable energy in total energy production. In this context, the co-digestion of various waste streams seems an interesting option. This study aimed to determine the effect of selected pretreatment methods on the efficiency and kinetics of the co-digestion process of poultry manure with sewage sludge and organic waste. This research was carried out in four stages: (1) the selection of the third component of the co-digestion mixture; (2) the determination of the most favorable inoculum-to-substrate ratio for the co-digestion mixture; (3) the selection of the most favorable pretreatment parameters based on changes in volatile fatty acids, ammonium nitrogen, extracellular polymers substances (EPS) and non-purgeable organic carbon (NPOC); and (4) the evaluation of anaerobic co-digestion based on the result of the BMP tests and kinetic studies. All the pretreatment methods increased the degree of organic matter liquefaction as measured by the NPOC changes. Waste with a high fat content showed the highest methane potential. The addition of grease trap sludge to feedstock increased methane yield from 320 mL/g VSadd to 340 mL/g VSadd. An optimal inoculum-to-substrate ratio was 2. The pretreatment methods, especially the thermochemical one with NaOH, increased the liquefaction of organic matter and the methane yield, which increased from 340 mL/g VSadd to 501 mL/g VSadd (trial with 4.5 g/L NaoH).
Advanced Levelized Cost Evaluation Method for Electric Vehicle Stations Concurrently Producing Electricity and Hydrogen
Authors: Tahir Mustafa , Hu Sideng , Zhu Haoqi
Published: May 2024

This study develops a new method to evaluate the economic viability of co-generation electric vehicle stations that concurrently generate electricity and hydrogen for charging battery electric vehicles and refueling hydrogen vehicles. The approach uniquely differentiates the costs associated with various energy outputs in co-generation stations and includes often-overlooked peripheral devices critical for accurate evaluation of the levelized cost of electricity (LCOE) and hydrogen (LCOH). The method was tested across three design configurations: two featuring single storage options (battery and fuel cell, respectively) and a third using hybrid storage employing both. Each configuration was modeled, simulated, and optimized using HOMER Pro 3.14.2 to determine the most optimal sizing solution. Then, based on the optimal sizing of each design, LCOE and LCOH were evaluated using the proposed method in this study. The analysis revealed that excluding often-overlooked peripheral devices could lead to a 27.7% error in LCOH evaluation, while the impact on LCOE was less than 1%. Among different configurations, the design with hybrid storage proved economically superior, achieving a total levelized cost of energy (TLCOE) for the entire system of USD 0.113/kWh, with the LCOE at USD 0.025/kWh and LCOH at USD 0.088/kWh (or USD 3.46/kg). Comparative analysis with state-of-the-art studies confirmed the accuracy of the proposed method. This study provides a more precise and holistic approach that can be leveraged for the feasibility analysis of electric vehicle stations globally, enhancing strategic decision-making in sustainable energy planning.
Integrative ATAC-seq and RNA-seq Analysis of the Longissimus Dorsi Muscle of Gannan Yak and Jeryak
Authors: Zhao Zhidong , Guo Dashan , Wei Yali , Li Jingsheng , Jia Xue , Niu Yanmei , Liu Zhanxin , Bai Yanbin , Chen Zongchang , Shi Bingang , Zhang Xiaolan , Hu Jiang , Wang Jiqing , Liu Xiu , Li Shaobin
Published: May 2024

Jeryak is the F1 generation of the cross between Gannan yak and Jersey cattle, which has the advantages of fast growth and high adaptability. The growth and development of skeletal muscle is closely linked to meat production and the quality of meat. However, the molecular regulatory mechanisms of muscle growth differences between Gannan yak and Jeryak analyzed from the perspective of chromatin opening have not been reported. In this study, ATAC-seq was used to analyze the difference of chromatin openness in longissimus muscle of Gannan yak and Jeryak. It was found that chromatin accessibility was more enriched in Jeryak compared to Gannan yak, especially in the range of the transcription start site (TSS) ± 2 kb. GO and KEGG enrichment analysis indicate that differential peak-associated genes are involved in the negative regulation of muscle adaptation and the Hippo signaling pathway. Integration analysis of ATAC-seq and RNA-seq revealed overlapping genes were significantly enriched during skeletal muscle cell differentiation and muscle organ morphogenesis. At the same time, we screened FOXO1, ZBED6, CRY2 and CFL2 for possible involvement in skeletal muscle development, constructed a genes and transcription factors network map, and found that some transcription factors (TFs), including YY1, KLF4, KLF5 and Bach1, were involved in skeletal muscle development. Overall, we have gained a comprehensive understanding of the key factors that impact skeletal muscle development in various breeds of cattle, providing new insights for future analysis of the molecular regulatory mechanisms involved in muscle growth and development.
Optimizing Antimicrobial Peptide Design: Integration of Cell-Penetrating Peptides, Amyloidogenic Fragments, and Amino Acid Residue Modifications
Authors: Kravchenko Sergey V. , Domnin Pavel A. , Grishin Sergei Y. , Zakhareva Alena P. , Zakharova Anastasiia A. , Mustaeva Leila G. , Gorbunova Elena Y. , Kobyakova Margarita I. , Surin Alexey K. , Poshvina Darya V. , Fadeev Roman S. , Azev Viacheslav N. , Ostroumova Olga S. , Ermolaeva Svetlana A. , Galzitskaya Oxana V.
Published: May 2024

The escalating threat of multidrug-resistant pathogens necessitates innovative approaches to combat infectious diseases. In this study, we examined peptides R23FS*, V31KS*, and R44KS*, which were engineered to include an amyloidogenic fragment sourced from the S1 protein of S. aureus, along with one or two cell-penetrating peptide (CPP) components. We assessed the antimicrobial efficacy of these peptides in a liquid medium against various strains of both Gram-positive bacteria, including S. aureus (209P and 129B strains), MRSA (SA 180 and ATCC 43300 strains), and B. cereus (strain IP 5832), and Gram-negative bacteria such as P. aeruginosa (ATCC 28753 and 2943 strains) and E. coli (MG1655 and K12 strains). Peptides R23FS*, V31KS*, and R44KS* exhibited antimicrobial activity comparable to gentamicin and meropenem against all tested bacteria at concentrations ranging from 24 to 48 μM. The peptides showed a stronger antimicrobial effect against B. cereus. Notably, peptide R44KS* displayed high efficacy compared to peptides R23FS* and V31KS*, particularly evident at lower concentrations, resulting in significant inhibition of bacterial growth. Furthermore, modified peptides V31KS* and R44KS* demonstrated enhanced inhibitory effects on bacterial growth across different strains compared to their unmodified counterparts V31KS and R44KS. These results highlight the potential of integrating cell-penetrating peptides, amyloidogenic fragments, and amino acid residue modifications to advance the innovation in the field of antimicrobial peptides, thereby increasing their effectiveness against a broad spectrum of pathogens.
Genome-Wide Identification and Characterization of miRNAs and Natural Antisense Transcripts Show the Complexity of Gene Regulatory Networks for Secondary Metabolism in Aristolochia contorta
Authors: Liang Wenjing , Xu Yayun , Cui Xinyun , Li Caili , Lu Shanfa
Published: May 2024

Aristolochia contorta Bunge is an academically and medicinally important plant species. It belongs to the magnoliids, with an uncertain phylogenetic position, and is one of the few plant species lacking a whole-genome duplication (WGD) event after the angiosperm-wide WGD. A. contorta has been an important traditional Chinese medicine material. Since it contains aristolochic acids (AAs), chemical compounds with nephrotoxity and carcinogenicity, the utilization of this plant has attracted widespread attention. Great efforts are being made to increase its bioactive compounds and reduce or completely remove toxic compounds. MicroRNAs (miRNAs) and natural antisense transcripts (NATs) are two classes of regulators potentially involved in metabolism regulation. Here, we report the identification and characterization of 223 miRNAs and 363 miRNA targets. The identified miRNAs include 51 known miRNAs belonging to 20 families and 172 novel miRNAs belonging to 107 families. A negative correlation between the expression of miRNAs and their targets was observed. In addition, we identified 441 A. contorta NATs and 560 NAT-sense transcript (ST) pairs, of which 12 NATs were targets of 13 miRNAs, forming 18 miRNA-NAT-ST modules. Various miRNAs and NATs potentially regulated secondary metabolism through the modes of miRNA-target gene–enzyme genes, NAT-STs, and NAT-miRNA-target gene–enzyme genes, suggesting the complexity of gene regulatory networks in A. contorta. The results lay a solid foundation for further manipulating the production of its bioactive and toxic compounds.
NPC Intracellular Cholesterol Transporter 1 Regulates Ovarian Maturation and Molting in Female Macrobrachium nipponense
Authors: Jiang Sufei , Zhang Wenyi , Xiong Yiwei , Zhang Mengying , Yuan Huwei , Niu Yunpeng , Qiao Hui , Fu Hongtuo
Published: May 2024

NPC intracellular cholesterol transporter 1 (NPC1) plays an important role in sterol metabolism and transport processes and has been studied in many vertebrates and some insects, but rarely in crustaceans. In this study, we characterized NPC1 from Macrobrachium nipponense (Mn-NPC1) and evaluated its functions. Its total cDNA length was 4283 bp, encoding for 1344 amino acids. It contained three conserved domains typical of the NPC family (NPC1_N, SSD, and PTC). In contrast to its role in insects, Mn-NPC1 was mainly expressed in the adult female hepatopancreas, with moderate expression in the ovary and heart. No expression was found in the embryo (stages CS–ZS) and only weak expression in the larval stages from hatching to the post-larval stage (L1–PL15). Mn-NPC1 expression was positively correlated with ovarian maturation. In situ hybridization showed that it was mainly located in the cytoplasmic membrane and nucleus of oocytes. A 25-day RNA interference experiment was employed to illustrate the Mn-NPC1 function in ovary maturation. Experimental knockdown of Mn-NPC1 using dsRNA resulted in a marked reduction in the gonadosomatic index and ecdysone content of M. nipponense females. The experimental group showed a significant delay in ovarian maturation and a reduction in the frequency of molting. These results expand our understanding of NPC1 in crustaceans and of the regulatory mechanism of ovarian maturation in M. nipponense.
Endophytic Fungi from the Four Staple Crops and Their Secondary Metabolites
Authors: Fan Yinzhong , Shi Baobao
Published: May 2024

Endophytic fungi are present in every plant, and crops are no exception. There are more than 50,000 edible plant species on the planet, but only 15 crops provide 90 percent of the global energy intake, and “the big four”—wheat, rice, maize and potato—are staples for about 5 billion people. Not only do the four staple crops contribute to global food security, but the endophytic fungi within their plant tissues are complex ecosystems that have been under scrutiny. This review presents an outline of the endophytic fungi and their secondary metabolites in four staple crops: wheat, rice, maize and potato. A total of 292 endophytic fungi were identified from the four major crops, with wheat having the highest number of 157 endophytic fungi. Potato endophytic fungi had the highest number of secondary metabolites, totaling 204 compounds, compared with only 23 secondary metabolites from the other three crops containing endophytic fungi. Some of the compounds are those with specific structural and pharmacological activities, which may be beneficial to agrochemistry and medicinal chemistry.
Long-Term Pharmacokinetic Follow-Up of Abiraterone Acetate in Patients with Metastatic Castration-Resistant Prostate Cancer
Authors: Chamorey Emmanuel , Pujalte-Martin Marc , Ferrero Jean-Marc , Mahammedi Hakim , Gravis Gwenaelle , Roubaud Guilhem , Beuzeboc Philippe , Largillier Remy , Borchiellini Delphine , Linassier Claude , Bouges Hélène , Etienne-Grimaldi Marie-Christine , Schiappa Renaud , Gal Jocelyn , Milano Gérard
Published: May 2024

This ABIGENE pharmacokinetic (PK) study sought mainly to characterize the unchanged drug PK during long-term abiraterone acetate (AA) administration in advanced prostate cancer patients (81 patients). It was observed that individual AA concentrations remained constant over treatment time, with no noticeable changes during repeated long-term drug administration for up to 120 days. There was no correlation between AA concentrations and survival outcomes. However, a significant association between higher AA concentrations and better clinical benefit was observed (p = 0.041). The safety data did not correlate with the AA PK data. A significant positive correlation (r = 0.40, p < 0.001) was observed between mean AA concentration and patient age: the older the patient, the higher the AA concentration. Patient age was found to impact steady-state AA concentration: the older the patient, the higher the mean AA concentration. Altogether, these data may help to guide future research and clinical trials in order to maximize the benefits of AA metastatic castration-resistant prostate cancer patients.
A Humanized CB1R Yeast Biosensor Enables Facile Screening of Cannabinoid Compounds
Authors: Mulvihill Colleen J. , Lutgens Joshua D. , Gollihar Jimmy D. , Bachanová Petra , Tramont Caitlin , Marcotte Edward M. , Ellington Andrew D. , Gardner Elizabeth C.
Published: May 2024

Yeast expression of human G-protein-coupled receptors (GPCRs) can be used as a biosensor platform for the detection of pharmaceuticals. Cannabinoid receptor type 1 (CB1R) is of particular interest, given the cornucopia of natural and synthetic cannabinoids being explored as therapeutics. We show for the first time that engineering the N-terminus of CB1R allows for efficient signal transduction in yeast, and that engineering the sterol composition of the yeast membrane modulates its performance. Using an engineered cannabinoid biosensor, we demonstrate that large libraries of synthetic cannabinoids and terpenes can be quickly screened to elucidate known and novel structure–activity relationships. The biosensor strains offer a ready platform for evaluating the activity of new synthetic cannabinoids, monitoring drugs of abuse, and developing therapeutic molecules.
Mesenchymal Stromal Cell-Based Products: Challenges and Clinical Therapeutic Options
Authors: Mello Debora B. , Mesquita Fernanda Cristina Paccola , Silva dos Santos Danúbia , Asensi Karina Dutra , Dias Marlon Lemos , Campos de Carvalho Antonio Carlos , Goldenberg Regina Coeli dos Santos , Kasai-Brunswick Tais Hanae
Published: May 2024

Mesenchymal stromal cell (MSC)-based advanced therapy medicinal products (ATMPs) are being tried in a vast range of clinical applications. These cells can be isolated from different donor tissues by using several methods, or they can even be derived from induced pluripotent stem cells or embryonic stem cells. However, ATMP heterogeneity may impact product identity and potency, and, consequently, clinical trial outcomes. In this review, we discuss these topics and the need to establish minimal criteria regarding the manufacturing of MSCs so that these innovative therapeutics may be better positioned to contribute to the advancement of regenerative medicine.
Employing Genomic Tools to Explore the Molecular Mechanisms behind the Enhancement of Plant Growth and Stress Resilience Facilitated by a Burkholderia Rhizobacterial Strain
Authors: Chang Yueh-Long , Chang Yu-Cheng , Kurniawan Andi , Chang Po-Chun , Liou Ting-Yu , Wang Wen-Der , Chuang Huey-wen
Published: May 2024

The rhizobacterial strain BJ3 showed 16S rDNA sequence similarity to species within the Burkholderia genus. Its complete genome sequence revealed a 97% match with Burkholderia contaminans and uncovered gene clusters essential for plant-growth-promoting traits (PGPTs). These clusters include genes responsible for producing indole acetic acid (IAA), osmolytes, non-ribosomal peptides (NRPS), volatile organic compounds (VOCs), siderophores, lipopolysaccharides, hydrolytic enzymes, and spermidine. Additionally, the genome contains genes for nitrogen fixation and phosphate solubilization, as well as a gene encoding 1-aminocyclopropane-1-carboxylate (ACC) deaminase. The treatment with BJ3 enhanced root architecture, boosted vegetative growth, and accelerated early flowering in Arabidopsis. Treated seedlings also showed increased lignin production and antioxidant capabilities, as well as notably increased tolerance to water deficit and high salinity. An RNA-seq transcriptome analysis indicated that BJ3 treatment significantly activated genes related to immunity induction, hormone signaling, and vegetative growth. It specifically activated genes involved in the production of auxin, ethylene, and salicylic acid (SA), as well as genes involved in the synthesis of defense compounds like glucosinolates, camalexin, and terpenoids. The expression of AP2/ERF transcription factors was markedly increased. These findings highlight BJ3’s potential to produce various bioactive metabolites and its ability to activate auxin, ethylene, and SA signaling in Arabidopsis, positioning it as a new Burkholderia strain that could significantly improve plant growth, stress resilience, and immune function.
Durability Analysis of Cold Spray Repairs: Phase I—Effect of Surface Grit Blasting
Authors: Peng Daren , Tang Caixian , Watts Jarrod , Ang Andrew , Raman R. K. Singh , Nicholas Michael , Phan Nam , Jones Rhys
Published: May 2024

This paper presents the results of an extensive investigation into the durability of cold spray repairs to corrosion damage in AA7075-T7351 aluminium alloy specimens where, prior to powder deposition, the surface preparation involved grit blasting. In this context, it is shown that the growth of small naturally occurring cracks in cold spray repairs to simulated corrosion damage can be accurately computed using the Hartman–Schijve crack growth equation in a fashion that is consistent with the requirements delineated in USAF Structures Bulletin EZ-SB-19-01, MIL-STD-1530D, and the US Joint Services Structural Guidelines JSSG2006. The relatively large variation in the da/dN versus ΔK curves associated with low values of da/dN highlights the fact that, before any durability assessment of a cold spray repair to an operational airframe is attempted, it is first necessary to perform a sufficient number of tests so that the worst-case small crack growth curve needed to perform the mandated airworthiness certification analysis can be determined.
Stress and Microstructures Characterization Based on Magnetic Incremental Permeability and Magnetic Barkhausen Noise Techniques
Authors: Sheng Hongwei , Wang Ping , Yang Yuan , Tang Chenglong
Published: May 2024

Both microstructure and stress affect the structure and kinematic properties of magnetic domains. In fact, microstructural and stress variations often coexist. However, the coupling of microstructure and stress on magnetic domains is seldom considered in the evaluation of microstructural characteristics. In this investigation, Magnetic incremental permeability (MIP) and magnetic Barkhausen noise (MBN) techniques are used to study the coupling effect of characteristic microstructure and stress on the reversible and irreversible motions of magnetic domains, and the quantitative relationship between microstructure and magnetic domain characteristics is established. Considering the coupling effect of microstructure and stress on magnetic domains, a patterned characterization method of microstructure and stress is innovatively proposed. Pattern recognition based on the Multi-layer Perceptron (MLP) model is realized for microstructure and stress with an accuracy rate higher than 97%. The results show that the pattern recognition accuracy of magnetic domain features and micro-magnetic features simultaneously as input parameters is higher than that of micro-magnetic features alone as input parameters.
Application of Independent Component Analysis and Nelder–Mead Particle Swarm Optimization Algorithm in Non-Contact Blood Pressure Estimation
Authors: Su Te-Jen , Lin Wei-Hong , Zhuang Qian-Yi , Hung Ya-Chung , Yang Wen-Rong , He Bo-Jun , Wang Shih-Ming
Published: May 2024

In recent years, hypertension has become one of the leading causes of illness and death worldwide. Changes in lifestyle among the population have led to an increasing prevalence of hypertension. This study proposes a non-contact blood pressure estimation method that allows patients to conveniently monitor their blood pressure values. By utilizing a webcam to track facial features and the region of interest (ROI) for obtaining forehead images, independent component analysis (ICA) is employed to eliminate artifact signals. Subsequently, physiological parameters are calculated using the principle of optical wave reflection. The Nelder–Mead (NM) simplex method is combined with the particle swarm optimization (PSO) algorithm to optimize the empirical parameters, thus enhancing computational efficiency and accurately determining the optimal solution for blood pressure estimation. The influences of light intensity and camera distance on the experimental results are also discussed. Furthermore, the measurement time is only 10 s. The superior accuracy and efficiency of the proposed methodology are demonstrated by comparing them with those in other published literature.
Evaluation of Lateral Radar Positioning for Vital Sign Monitoring: An Empirical Study
Authors: Hornig Lars , Szmola Benedek , Pätzold Wiebke , Vox Jan Paul , Wolf Karen Insa
Published: May 2024

Vital sign monitoring is dominated by precise but costly contact-based sensors. Contactless devices such as radars provide a promising alternative. In this article, the effects of lateral radar positions on breathing and heartbeat extraction are evaluated based on a sleep study. A lateral radar position is a radar placement from which multiple human body zones are mapped onto different radar range sections. These body zones can be used to extract breathing and heartbeat motions independently from one another via these different range sections. Radars were positioned above the bed as a conventional approach and on a bedside table as well as at the foot end of the bed as lateral positions. These positions were evaluated based on six nights of sleep collected from healthy volunteers with polysomnography (PSG) as a reference system. For breathing extraction, comparable results were observed for all three radar positions. For heartbeat extraction, a higher level of agreement between the radar foot end position and the PSG was found. An example of the distinction between thoracic and abdominal breathing using a lateral radar position is shown. Lateral radar positions could lead to a more detailed analysis of movements along the body, with the potential for diagnostic applications.
PP-ISEA: An Efficient Algorithm for High-Resolution Three-Dimensional Geometry Reconstruction of Space Targets Using Limited Inverse Synthetic Aperture Radar Images
Authors: Wang Rundong , Zhu Weigang , Li Chenxuan , Zhu Bakun , Pang Hongfeng
Published: May 2024

As the variety of space targets expands, two-dimensional (2D) ISAR images prove insufficient for target recognition, necessitating the extraction of three-dimensional (3D) information. The 3D geometry reconstruction method utilizing energy accumulation of ISAR image sequence (ISEA) facilitates superior reconstruction while circumventing the laborious steps associated with factorization methods. Nevertheless, ISEA’s neglect of valid information necessitates a high quantity of images and elongated operation times. This paper introduces a partitioned parallel 3D reconstruction method utilizing sorted-energy semi-accumulation with ISAR image sequences (PP-ISEA) to address these limitations. The PP-ISEA innovatively incorporates a two-step search pattern—coarse and fine—that enhances search efficiency and conserves computational resources. It introduces a novel objective function ‘sorted-energy semi-accumulation’ to discern genuine scatterers from spurious ones and establishes a redundant point exclusion module. Experiments on the scatterer model and simulated electromagnetic model demonstrate that the PP-ISEA reduces the minimum image requirement from ten to four for high-quality scatterer model reconstruction, thereby offering superior reconstruction quality in less time.
Swing Trend Prediction of Main Guide Bearing in Hydropower Units Based on MFS-DCGNN
Authors: Li Xu , Xu Zhuofei , Guo Pengcheng
Published: May 2024

Hydropower units are the core equipment of hydropower stations, and research on the fault prediction and health management of these units can help improve their safety, stability, and the level of reliable operation and can effectively reduce costs. Therefore, it is necessary to predict the swing trend of these units. Firstly, this study considers the influence of various factors, such as electrical, mechanical, and hydraulic swing factors, on the swing signal of the main guide bearing y-axis. Before swing trend prediction, the multi-index feature selection algorithm is used to obtain suitable state variables, and the low-dimensional effective feature subset is obtained using the Pearson correlation coefficient and distance correlation coefficient algorithms. Secondly, the dilated convolution graph neural network (DCGNN) algorithm, with a dilated convolution graph, is used to predict the swing trend of the main guide bearing. Existing GNN methods rely heavily on predefined graph structures for prediction. The DCGNN algorithm can solve the problem of spatial dependence between variables without defining the graph structure and provides the adjacency matrix of the graph learning layer simulation, avoiding the over-smoothing problem often seen in graph convolutional networks; furthermore, it effectively improves the prediction accuracy. The experimental results showed that, compared with the RNN-GRU, LSTNet, and TAP-LSTM algorithms, the MAEs of the DCGNN algorithm decreased by 6.05%, 6.32%, and 3.04%; the RMSEs decreased by 9.21%, 9.01%, and 2.83%; and the CORR values increased by 0.63%, 1.05%, and 0.37%, respectively. Thus, the prediction accuracy was effectively improved.
The Rape of the Lock d’Alexander Pope par Pierre Vinclair : une retraduction à distance
Authors: Métayer Guillaume
Published: May 2024

Cet article propose une mise en perspective de la dernière retraduction, contemporaine (2019) après un long silence, et publiée dans une revue d’avant-garde en ligne (Catastrophes) par le jeune poète Pierre Vinclair, d’un texte canonique, The Rape of the Lock d’Alexander Pope (1717). S’intéressant notamment à son titre et à l’aspect formel de cette retraduction, il inscrit ce dernier geste dans un panorama précis de l’histoire des traductions en langue française de ce poème clé des relations littéraires franco-anglaises au XVIIIe siècle et, par là, des évolutions socioéconomiques profondes dont les deux rives de la Manche ont été le théâtre, suggérant l’existence d’un moment tardif de la retraduction où celle-ci peut se permettre un équilibre inédit entre fidélité formelle et liberté de ton contemporain.
La compétence technique : la malaimée des concours et examens de traduction ?
Authors: Anckaert Philippe
Published: May 2024

Dans cet article, Philippe Anckaert base sa définition de la compétence technique sur trois ressources de référence : la norme ISO 17100, la description de la sous-compétence instrumentale du modèle théorique du groupe PACTE et le référentiel de compétence de l’EMT. Face à la belle unanimité des ténors de la profession, de la recherche et de l’enseignement quant à l’importance de la compétence technique dans le processus de traduction, l’auteur souligne la quasi-inexistence d’une évaluation spécifique et rigoureuse de cette compétence lors de la sélection de candidat• es traducteur• rices dans la fonction publique. Pour illustrer l’ampleur du phénomène, il analyse et compare les pratiques évaluatives observées cette dernière décennie lors des concours de recrutement organisés par un échantillon représentatif d’organisations publiques belges. L’analyse comprend un volet explicatif des raisons pour lesquelles on renonce souvent à évaluer la compétence technique des traducteur•rices. Elle est assortie d’une série de propositions concrètes de formats d’épreuves susceptibles de garantir une évaluation fidèle et valide de la compétence de traduction intégrant la composante technique ou instrumentale.
أثر تطبيق معايير منهج سيجما ستة في تحسين جَوْدة المراجعة الداخلية في البنوك السودانية: دراسة ميدانية
Authors: عبد العزيز جعفر عثمان الشريف
Published: May 2024

هدف الدراسة: هدفت هذه الدراسة إلى اختبار أثر تطبيق معايير منهج سيجما ستة في تحسين جَوْدة المراجعة الداخلية في البنوك السودانية.تصميم/منهجية/طريقة الدراسة: اعتمدت الدراسة على قائمة استبيان، انطوت على مجموعة من التساؤلات؛ لاستطلاع آراء المستقصى منهم، وتحقيق الهدف من الدراسة.عينة الدراسة وبياناتها: أجريت الدراسة الميدانية على عينة عشوائية مكونة من (175) فردًا من المراجعين الداخليين، وأعضاء لجان المراجعة في البنوك، وموظفي الإدارة العامة للرقابة المصرفية في بنك السودان المركزي.نتائج الدراسة: توصلت الدراسة إلى وجود أثر معنوي إيجابي دالّ إحصائيًّا، بدرجة كبيرة، لتطبيق معايير منهج سيجما ستة على المراجعة الداخلية في البنوك السودانية من حيثُ تحسينُ جَوْدتها؛ وهذا ما يعطي مؤشرًا إيجابيًّا على إمكانية الاستفادة من تطبيق هذه المعايير في المنشآت المختلفة في بيئة الأعمال السودانية.أصالة الدراسة: تُعد الدراسة من الدراسات الأولى التي تناولت قياس أثر تطبيق معايير منهج سيجما ستة في تحسين جَوْدة المراجعة الداخلية في البنوك السودانية.حدود الدراسة وتطبيقاتها: اقتصرت الدراسة على عينة من المراجعين الداخليين، وأعضاء لجان المراجعة الذين يعملون في البنوك السودانية، وعينة من موظفي الإدارة العامة للرقابة المصرفية في بنك السودان المركزي.
Entrepreneurship Education Study: Change Management and Entrepreneurial Dreams
Authors: Aristiyanto Roma
Published: May 2024

This article aims to elucidate the concept of change management within the realm of education and explores how nurturing entrepreneurial dreams in the field of education can serve as a key to fostering innovation in the educational sphere. The research methodology employed in this article is based on an extensive review of pertinent literature and the analysis of relevant scholarly works to identify the role of change management in education and delve into the influence of entrepreneurial dreams on educational innovation. The findings of this study provide a comprehensive understanding of the concept of change management in education and delineate concrete steps that can be taken to cultivate entrepreneurial dreams in the field of education. Emphasis is placed on the importance of identifying necessary changes, change planning, effective communication, skill development, networking, and overcoming resistance to change in the pursuit of educational objectives.
Using Podcasts to Improve Listening Skills in Pharmacy Students
Authors: Desmiyanti
Published: May 2024

Language is a system of communication used by a community or group of people. Listening is an important skill in interacting with others in everyday life. This study aims to see how (1) The theoretical perspective of the use of Podcasts on English (2) The use of Podcasts in English courses to improve Listening Skills in Pharmacy Students. This research is a type of qualitative method through literature study. This method referred to as qualitative literature analysis, involves the review and interpretation of descriptive, interpretative, or qualitative analysis of library materials. The results of this study (1)The theoretical perspective of the use of Podcasts on English, namely based on the research that has been done, students feel the positive impact of using Podcasts in teaching English. Students have a fairly good perception of the use podcasts in improving English listening skills. (2)The use of Podcasts in improving listening skills in pharmacy students that is podcasts are able to increase understanding and absorption of information. Pharmacy students can improve listening skills in the health sector. How to improve listening skills is one of them by listening to podcasts.
keywords: Podcasts, Listening Skills, Pharmacy Students
Modern methods of cognitive functions analysis (literature review, part 1)
Authors: Maslova N.M. , Bulynina O.D.
Published: May 2024

In the field of modern medicine, there is a significant focus on addressing cognitive impairments due to their widespread prevalence and substantial impact on patients' quality of life. The human brain's cognitive functions are closely tied to a wide range of structural and functional characteristics of individual brain regions, as well as the specific interactions between these regions. When individuals engage in cognitive activities, such as solving complex tasks, the efficiency of processing and transmitting information between different brain areas becomes a key consideration. Each of these brain regions is meticulously designed to assess various neuropsychological functions, including memory, language, executive function, abstract thinking, attention, and visuospatial abilities. Recently, healthcare professionals and researchers have been increasingly focusing on pre-dementia (mild and moderate) cognitive impairments. The spectrum of cognitive impairments in the elderly is broad, encompassing not only dementia and Alzheimer's disease but also less severe, moderate cognitive impairments. Assessment tools vary, ranging from those designed to evaluate a single neuropsychological domain to comprehensive neuropsychological testing, which evaluates all neuropsychological domains. This review provides an analysis of the most common modern methods, including classical neuropsychological tests and the use of eye-tracking technology, which offers quantitative assessment and sensitive detection of cognitive impairments in conditions such as dementia, concussion, traumatic brain injuries, autism spectrum disorders, and attention deficit hyperactivity disorder, among others. The review also discusses the advantages and limitations of these methodologies, highlighting the necessity of a comprehensive approach to assessing cognitive functions. This comprehensive approach is crucial for diagnosing both severe and mild cognitive impairments, evaluating brain damage, determining decision-making capacity, and testing for intellectual disabilities.

Keywords: psychophysiological tests, brain, cognitive disorders, screening test, dementia.
La comunicación visual en las aulas de la UNLP
Authors:   , Calvente Paula Elena
Published: May 2024

La comunicación visual aparece como una disciplina invisible en el trayecto educativo. Puntualmente en el nivel universitario prácticamente no es posible encontrar formación en el tema dentro de las currículas de grado, siendo una herramienta de uso cotidiano en la práctica docente, pero también en otros ámbitos profesionales como presentaciones en congresos, reuniones laborales, etc. La intención de esta tesis es poner de manifiesto el lugar que ocupa la comunicación visual, su uso e implementación y los conocimientos presentes sobre esta disciplina en la educación, principalmente en la formación profesional y su incidencia en la realización de mensajes. Es decir, qué importancia y relevancia tiene la comunicación visual hoy en el ámbito universitario, qué capacitación brinda el sistema educativo de grado a sus estudiantes y docentes, ¿se conocen cuáles son los saberes que acompañan a esta disciplina y los beneficios de su aplicación al poner en juego de forma consciente los elementos de la comunicación visual al armar, en este caso, las pantallas? La propuesta de este trabajo no busca sostener que todos los docentes y futuros egresados de la UNLP deberían ser diseñadores en comunicación visual, ni especialistas en la realización de esquemas complejos o imágenes didácticas, (quehaceres que necesitan de mayores conocimientos de los que planteamos e intentamos abordar en esta tesis), en el sentido que tampoco se busca al enseñarnos a armar textos coherentes, las reglas ortográficas o el análisis sintáctico, que seamos especialistas en disciplinas como la lingüística o la literatura.
State Fulfillment of Indonesian Children’s Civil Rights for Former Members of International Terrorist Organization
Authors: Muhammad Syam Riva'i  , Davilla Prawidya Azaria
Published: May 2024

As the defeated Islamic State of Iraq and Syria (ISIS) raises neglected misfortune for Indonesian children whose parents once participated in the organization. Indonesia's Government's decision to repatriate has not yet been fully executed while circulating threatened punishment by the Government to withdraw the nationality of a person involved in ISIS to make it worse. In contrast, international law safeguards civil rights for children despite their status of unwillingly participating in terrorist organizations. Normative juridical research was conducted by taking statutory and conceptual approaches to examine national regulation of children's civil rights legal protection. The result shows that children's civil rights ex-ISIS remain valid as their indivisible fundamental rights while state compliance is necessary. Redefining children's status as children of terrorist network victims is mentioned in Article 59 (2) (k) of Law No. 35/2014 concerning Children's Protection. With a status as a victim, a particular procedure can be executed to restore and safeguard child civil rights. Ministry of Women Empowerment and Child Protection (Kemen PPPA) coordinates with National Counter Terrorism Agency (BNPT) mandates to exercise legal aid to provide education, counselling, rehabilitation, and social assistance.
Role of Labour Inspector in Preventing and Overcoming Child Labour Exploitation: A Critical Review
Authors: Prawira M. Rizki Yudha , Muhammad Raihan Yulistio
Published: May 2024

The right to decent work is a fundamental human right that applies to everyone without exception, including children. This is clearly stated in several Indonesian laws, such as Law No. 39 of 1999 concerning Human Rights, Law No. 13 of 2003 concerning Manpower, and Law No. 23 of 2002 in conjunction with Law No. 35 of 2014 concerning Children. Although many legal provisions aim to protect children from exploitation in the workplace, the situation still needs improvement due to a lack of effective implementation. The labour inspectorate is responsible for enforcing these laws, but the number of inspectors is limited, and their authority often needs to be fully implemented. As a result, many children are still working in dangerous or exploitative conditions, which is unacceptable. Therefore, it is crucial to strengthen the labour inspectorate's role by increasing the number of implementing personnel and improving their authority's effectiveness to ensure child labours’ protection.
STRATEGIC FRAMEWORK FOR THE DEVELOPMENT OF BIOREGIONS IN LATVIA
Authors: Kaufmane Dace , Proskina Daniela , Proskina Liga
Published: May 2024

Human activity on the planet has created ecological problems, and it is necessary to find new solutions to the sustainable development of rural areas, thereby affecting the rural areas socially, economically, culturally and environmentally. Sustainable development allows society to increase prosperity, and one of the pillars of prosperity is an attractive living environment. Modern society�s perception tends to change, highly appreciating the need for local economic development. Each country applies a different approach to achieving its sustainable development goals. One of the potential solutions in this context could be the establishment of bioregions. The establishment of bioregions in the European Union is still at the initial stage, and an assessment of the current situation is very urgent. A strategic framework in place at all policy-making levels is essential to ensure the sustainable use and preservation of natural resources and to promote regional cooperation and sustainable development. In Latvia, bioregions are a new concept, which has no specific legal framework. However, the establishment of potential bioregions is largely affected by multilateral agreements between the UN and EU Member States, which are binding on Latvia and aimed at sustainable development, biodiversity and mitigating climate change. The present research employed document analysis to identify bioregion establishment processes and the drivers thereof. The research aims to analyse the strategic policy documents in order to summarize the policy conceptions of sustainable territorial development for the establishment of bioregions. The research was conducted with the support of fundamental and applied research project No. lzp2022/1-0519 Bio-regions as an Integrated Strategy for Sustainable Rural Development in Latvia.
THE CORRESPONDENCE OF THE LAWYER IN ECHR JURISPRUDENCE AND OF THE ROMANIAN CONSTITUTIONAL COURT
Authors: Ni?oiu Lorena Gabriela
Published: May 2024

Correspondence between a lawyer and his client, regardless of its purpose, is protected under article 8 of the Convention, which gives it increased protection in terms of confidentiality. In Romania, the Constitutional Court considers regarding the correspondence between a lawyer and his client, that it contributes essentially to the defense of the client, being an intrinsic element of the fundamental right to defense, enshrined in article 24 of the Constitution. Therefore, the lawyer-client relationship is qualified as a privileged one. The analysis of the Constitutional Court must have as a premise the privileged status of lawyer-client correspondence, which benefits from a specific legal treatment, without putting the sign of equality between this and ordinary correspondence between individuals. Romania must regulate a normative framework capable of providing additional protection for this type of correspondence.
Las voces del territorio: una experiencia de cultura científica en el Tolima
Authors: Tafur Osorio Marly Viviana , Sánchez Rubio Yenny Marcela , Henao Morales Laura Yamile , Mazorco-Salas Julio Eduardo , Chiquillo Valencia Carlos Manuel
Published: May 2024

En esta publicación, el lector se encontrará con los elementos teóricos y de problematización de las categorías de apropiación social del conocimiento, cultura científica, ciencia ciudadana y ciencia, tecnología e innovación. Así mismo, hallará un aparado metodológico con una propuesta de sistematización de experiencias. Finalmente, verá los resultados y las conclusiones que surgen a partir de la experiencia del proyecto CreaCiencia, cuyo propósito es fortalecer la cultura científica en instituciones educativas del departamento del Tolima en Colombia.
Development of an integrative learning model for character education based on islamic values of the koran and hadith in boarding school
Authors: Ginanjar Yogi Elia , Yahya Muhammad , Samana Abdul
Published: May 2024

Purpose: This study aims to develop an integrative learning model to improve student character based on Islamic values sourced from the Qur'an and Hadith. This Research and Development research (research and development) using 4D development techniques (Define, Design, Development, and Disseminate).
Method: The study was conducted at Insan Scholar Madani Serpong High School. Data were obtained through interviews, questionnaires, documentation, and observations. The interview, documentation, and observation instruments were analyzed using descriptive qualitative analysis, whereas the questionnaire instruments were analyzed using independent T test statistical analysis.
Results: The results revealed that 1) the factual conditions of the learning process at Insan Scholar Madani High School before using the integrative learning model of character education based on Islamic values still used conventional learning, and there had been efforts to carry out contextual learning, but it was not effective. After using the integrative learning model, the learning process shows that this model has high benefits for students, a high level of ease of application, attracts students to participate in learning, and motivates students in the learning process. 2) Preparation of the initial design for integrative learning includes several phases: open, causal, hypothetical, and closed. The initial draft development steps included the development of syntax, social systems, response principles, support tools, instructional impacts, and derivative impacts. 3) Model development was validated through three validators: learning model expert validators, character development expert validators, and learning practitioner validators. 4) There was a significant difference in effectiveness between the use of integrative learning methods in the experimental class and conventional models in the control class in improving the character of students' Islamic values at the Insan Scholar Madani High School. Practicality is obtained from the results of evaluations carried out by teachers; this model has very good syntax, can be implemented well, and has very good assessment tools.
The influence of social media on students of second-cycle institutions in Tamale and its implications
Authors: Mohammed Taufic Yabang , Philip Kukura Yirinibe , Labaran Kanita
Published: May 2024

Purpose: This study investigated the influence of social media on students in second-cycle institutions in Tamale. It concentrates on its relationship with academic performance, learning ability, writing skills, and gender disparities in usage patterns.
Methodology/approach: A purposive sample method was employed to select 150 students from secondary schools in Tamale. Data were collected through surveys and interviews using both qualitative and quantitative approaches to explore how social media affects students’ academic experiences.
Results/Findings: Findings from this study indicate that the use of social media has a significant impact on students’ learning abilities, writing skills, and academic performance. A significant number of learners reported becoming distracted with reduced concentration because they spent excessive time on the sites, leading to possible health challenges and a sedentary lifestyle. The results also indicated that gender differences exist in social media usage patterns, among others, which affect school performance.
Limitations: One limitation of this research is that it had a small sample size and may not represent all students found within second-cycle institutions. This further implies that this research is constrained to a particular geographical area, limiting its generalizability.
Contribution: This study contributes to the understanding of how social media influences students in second-cycle institutions, highlighting the need for educators and policymakers to establish guidelines for responsible social media use to enhance academic success and mitigate its negative impacts.