bluuebunny/crossref_metadata_2025 huggingface dataset:
Physiological Changes of Wheat Varieties Under Water Deficit Condition
Authors: Tasmina T , Khan AR , Karim A , Akter N , Islam R
Published: March 2017

The experiment was carried out at the research field of the Department of Agronomy of Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur during November 2014 to March 2015 to assess and evaluate the physiological derivations of wheat varieties under water deficit condition. The experiment was laid out in a split plot design comprising two water regimes (irrigated or control and water stress) in main plot and three wheat varieties (BARI Gom 25, BARI Gom 26 and Sourav) in sub-plot with four replications. Surface irrigation was applied into the irrigated plots in total growing season but it was applied in water stress plots up to 21 days after sowing after that irrigation was stopped in water stress plots. It was revealed that studied parameters were significantly influenced by water regimes, variety and their interaction. The xylem exudation rate, light interception, SPAD value, leaf water potential, relative water content, water retention capacity was higher in irrigated condition where canopy temperature, water uptake capacity, water saturation deficit higher in water stress condition.The wheat var. BARI Gom 26 showed the highest PAR, SPAD value, leaf water potential, relative water content, water retention capacity where BARI Gom 25 exhibit lowest under water deficit condition. On the other hand, BARI Gom 25 showd the highest canopy temperature, water uptake capacity and water saturation deficit in water deficit condition. Therefore, considering the physiological performance and other characters BARI Gom 26 could be considered preferably for water shortage condition followed by Sourav where BARI Gom 25 was susceptible one.Bangladesh Agron. J. 2016 19(2): 105-114
‘The Poor Man's Son’ and the Corruption of Our Moral Sentiments: Commerce, Virtue and Happiness in Adam Smith
Authors: Hill Lisa
Published: March 2017

In order to operate effectively, modern capitalism depends on agents who evince a rather morally undemanding type of moral character; one that is acquisitive, pecuniary, recognition-seeking and merely prudent. Adam Smith is considered to have been the key legitimiser of this archetype.

In this paper I respond to the view that Smith is actually sceptical about the value of material acquisition and explore whether he really believed that the pursuit of tranquillity and virtue—especially beneficence—offers a superior route to happiness than the commercial world of materialist acquisition. I approach these issues partly by considering the roles of beneficence and sympathy in Smith's system and partly by analysing the story of ‘The Poor Man's Son’ related in Book IV of The Theory of Moral Sentiments. As he narrates this story, Smith seems highly critical of the unrelenting drive for worldly success. But what is the real moral of the story? Should people contain their ambition for recognition and material success and pursue tranquillity and virtue instead?

I suggest that Smith's discussion in and around the story of ‘The Poor Man's Son’ points to a significant tension between his personal ideal of happiness and his observations and recommendations as a social scientist.
‘The Man Within’: Adam Smith on Moral Autonomy and Religious Sentiments
Authors: Chen Jeng-Guo S.
Published: March 2017

This essay analyses the ethical importance and religious implications of ‘the man within’ in Adam Smith's moral philosophy. Not introduced until the second edition of Theory of Moral Sentiments, ‘the man within’ appears as the internalization of the impartial spectator. With the invention of the man within, Smith was able to explain how moral agents pursue virtues and behave morally beyond immediate and quotidian concerns with either praises or blames from society. Having complied with the general dictates of the impartial spectator with conscience, humans become morally autonomous individuals whose moral judgements are derived from constant dialogues with the man within in an ethical microcosm within their breasts. The man within possesses a transcendent nature that preempts social judgements. Because of that transcendent nature, Smith also denominated the man within as ‘the substitute of Deity’. This essay also argues that even conscientious and virtuous individuals can be wronged and misjudged by society. To Smith, religious sentiments were most likely generated among the morally autonomous, innocent people. Afflicted with devastating distranquility of the mind caused by misjudgments of society, the innocent can only find comfort in the hope for the afterlife. The essay concludes that Smith's religious view in this particular regard goes hand in hand with his great concern with justice prevailing in his writings of political economy, government and ethics.
Influence of Torrefaction on the Conversion Efficiency of the Gasification Process of Sugarcane Bagasse
Authors: Anukam Anthony , Mamphweli Sampson , Okoh Omobola , Reddy Prashant
Published: March 2017

Sugarcane bagasse was torrefied to improve its quality in terms of properties prior to gasification. Torrefaction was undertaken at 300 °C in an inert atmosphere of N2 at 10 °C·min−1 heating rate. A residence time of 5 min allowed for rapid reaction of the material during torrefaction. Torrefied and untorrefied bagasse were characterized to compare their suitability as feedstocks for gasification. The results showed that torrefied bagasse had lower O–C and H–C atomic ratios of about 0.5 and 0.84 as compared to that of untorrefied bagasse with 0.82 and 1.55, respectively. A calorific value of about 20.29 MJ·kg−1 was also measured for torrefied bagasse, which is around 13% higher than that for untorrefied bagasse with a value of ca. 17.9 MJ·kg−1. This confirms the former as a much more suitable feedstock for gasification than the latter since efficiency of gasification is a function of feedstock calorific value. SEM results also revealed a fibrous structure and pith in the micrographs of both torrefied and untorrefied bagasse, indicating the carbonaceous nature of both materials, with torrefied bagasse exhibiting a more permeable structure with larger surface area, which are among the features that favour gasification. The gasification process of torrefied bagasse relied on computer simulation to establish the impact of torrefaction on gasification efficiency. Optimum efficiency was achieved with torrefied bagasse because of its slightly modified properties. Conversion efficiency of the gasification process of torrefied bagasse increased from 50% to approximately 60% after computer simulation, whereas that of untorrefied bagasse remained constant at 50%, even as the gasification time increased.
Computational Combination of the Optical Properties of Fenestration Layers at High Directional Resolution
Authors: Grobe Lars
Published: March 2017

Complex fenestration systems typically comprise co-planar, clear and scattering layers. As there are many ways to combine layers in fenestration systems, a common approach in building simulation is to store optical properties separate for each layer. System properties are then computed employing a fast matrix formalism, often based on a directional basis devised by JHKlems comprising 145 incident and 145 outgoing directions. While this low directional resolution is found sufficient to predict illuminance and solar gains, it is too coarse to replicate the effects of directionality in the generation of imagery. For increased accuracy, a modification of the matrix formalism is proposed. The tensor-tree format of RADIANCE, employing an algorithm subdividing the hemisphere at variable resolutions, replaces the directional basis. The utilization of the tensor-tree with interfaces to simulation software allows sharing and re-use of data. The light scattering properties of two exemplary fenestration systems as computed employing the matrix formalism at variable resolution show good accordance with the results of ray-tracing. Computation times are reduced to 0.4% to 2.5% compared to ray-tracing through co-planar layers. Imagery computed employing the method illustrates the effect of directional resolution. The method is supposed to foster research in the field of daylighting, as well as applications in planning and design.
A Settlers’ Guide: Designing for Resilience in the Hinterlands
Authors: Bryant Martin , Allan Penny , Kebbell Sam
Published: March 2017

There has often been a mutually beneficial relationship between cities and their rural hinterlands. The Kapiti region outside the city of Wellington in New Zealand is a prime example: it once provided Wellington’s food, water and cultural diversity for both Māori and European settlers. However, productivity-driven agriculture and extensive dormitory-suburbanization have affected significant parts of this once-abundant hinterland. Food production is becoming more mono-cultural, water quality is degrading, ecosystems’ biodiversity is disappearing, provincial town centres are shrinking, emigrating youth are leaving unbalanced demographics, Māori are increasingly disassociating their culture from their traditional lands and natural disasters are causing more impact—all of which is making Kapiti less resilient, and severing the once-healthy city-hinterland relationship. Our work on future settlement opportunities in Kapiti proposes alternatives, using experimental design-led research methods to develop speculative architectural and landscape architectural schemes. The schemes are framed by some of the spatial attributes of resilience: diversity, complexity, redundancy, interconnectivity and adaptability. Collectively, the work reveals design strategies that have a potential to rebuild hinterlands’ culture, town centres, housing, agriculture, community and ecosystems and to recalibrate the broader relationship between hinterlands and metropolitan systems.
Bioclimatic Analysis in Pre‐Design Stage of Passive House in Indonesia
Authors: Santy  , Matsumoto Hiroshi , Tsuzuki Kazuyo , Susanti Lusi
Published: March 2017

The objective of this study is to investigate the climate characteristics of Indonesian regions using an Olgyay Bioclimatic chart, a Givoni–Milne Bioclimatic chart and a Mahoney Table as the pre‐design stage in the development of a passive house design standard for residential house construction in Indonesia. Jakarta was the city chosen for deep analysis, because it represents most of the Indonesian regions in terms of temperature and relative humidity. The Olgyay Bioclimatic chart showed that the climate needs a high wind velocity to counteract the vapor pressure and shading in order to reduce solar gain entering the building. The Givoni–Milne Bioclimatic chart proposed natural ventilation and shading devices, while the Mahoney Table recommends open spaces for protection against hot wind, rooms single‐banked and permanent provision for air movement. The composite size of the opening at body height is better to allow the wind to counter the high levels of humidity and temperature. Heavy walls and roofs are suggested, as well as the provision of protection devices for the high amount of rainfall. Energy simulation was also done to investigate the effectiveness of the passive strategy proposed by the bioclimatic analysis. These results give a contribution as the indispensable basis for the development of a passive house standard in Indonesia.
Ozone Resistance, Water Permeability, and Concrete Adhesion of Metallic Films Sprayed on a Concrete Structure for Advanced Water Purification
Authors: Park Jin-Ho , Singh Jitendra , Lee Han-Seung
Published: March 2017

We evaluated the applicability of metal spray coating as a waterproofing/corrosion protection method for a concrete structure used for water purification. We carried out an ozone resistance test on four metal sprays and evaluated the water permeability and bond strength of the metals with superior ozone resistance, depending on the surface treatment method. In the ozone resistance test, four metal sprays and an existing ozone-proof paint were considered. In the experiment on the water permeability and bond strength depending on the surface treatment method, the methods of no treatment, surface polishing, and two types of pore sealing agents were considered. The results showed that the sprayed titanium had the best ozone resistance. Applying a pore sealing agent provided the best adhesion performance, of about 3.2 MPa. Applying a pore sealing agent also provided the best waterproofing performance. Scanning electron microscope analysis showed that applying a pore sealing agent resulted in an excellent waterproofing performance because a coating film formed on top of the metal spray coating. Thus, when using a metal spray as waterproofing/corrosion protection for a water treatment concrete structure, applying a pore sealing agent on top of a film formed by spraying titanium was concluded to be the most appropriate method.
Formulation of Exergy Cost Analysis to Graph-Based Thermal Network Models
Authors: Coss Stefano , Guelpa Elisa , Letournel Etienne , Le-Corre Olivier , Verda Vittorio
Published: March 2017

Information from exergy cost analysis can be effectively used in the design and management of modern district heating networks (DHNs) since it allows to properly account for the irreversibilities in energy conversion and distribution. Nevertheless, this requires the development of suitable graph-based approaches that are able to effectively consider the network topology and the variations of the physical properties of the heating fluid on a time-dependent basis. In this work, a formulation of exergetic costs suitable for large graph-based networks is proposed, which is consistent with the principles of exergetic costing. In particular, the approach is more compact in comparison to straightforward approaches of exergetic cost formulation available in the literature, especially when applied to fluid networks. Moreover, the proposed formulation is specifically considering transient operating conditions, which is a crucial feature and a necessity for the analysis of future DHNs. Results show that transient effects of the thermodynamic behavior are not negligible for exergy cost analysis, while this work offers a coherent approach to quantify them.
Reliability Assessment of Power Generation Systems Using Intelligent Search Based on Disparity Theory
Authors: Ali Kadhem Athraa , Abdul Wahab Noor , Aris Ishak , Jasni Jasronita , Abdalla Ahmed
Published: March 2017

The reliability of the generating system adequacy is evaluated based on the ability of the system to satisfy the load demand. In this paper, a novel optimization technique named the disparity evolution genetic algorithm (DEGA) is proposed for reliability assessment of power generation. Disparity evolution is used to enhance the performance of the probability of mutation in a genetic algorithm (GA) by incorporating features from the paradigm into the disparity theory. The DEGA is based on metaheuristic searching for the truncated sampling of state-space for the reliability assessment of power generation system adequacy. Two reliability test systems (IEEE-RTS-79 and (IEEE-RTS-96) are used to demonstrate the effectiveness of the proposed algorithm. The simulation result shows the DEGA can generate a larger variety of the individuals in an early stage of the next population generation. It is also able to estimate the reliability indices accurately.
Indoor Air Quality Assessment and Study of Different VOC Contributions within a School in Taranto City, South of Italy
Authors: Marzocca Annalisa , Di Gilio Alessia , Farella Genoveffa , Giua Roberto , De Gennaro Gianluigi
Published: March 2017

Children spend a large amount of time in school environments and when Indoor Air Quality (IAQ) is poor, comfort, productivity and learning performances may be affected. The aim of the present study is to characterize IAQ in a primary school located in Taranto city (south of Italy). Because of the proximity of a large industrial complex to the urban settlement, this district is one of the areas identified as being at high environmental risk in Italy. The study carried out simultaneous monitoring of indoor and outdoor Volatile Organic Compounds (VOC) concentrations and assessed different pollutants’ contributions on the IAQ of the investigated site. A screening study of VOC and determination of Benzene, Toluene, Ethylbenzene, Xylenes (BTEX), sampled with Radiello® diffusive samplers suitable for thermal desorption, were carried out in three classrooms, in the corridor and in the yard of the school building. Simultaneously, Total VOC (TVOC) concentration was measured by means of real-time monitoring, in order to study the activation of sources during the monitored days. The analysis results showed a prevalent indoor contribution for all VOC except for BTEX which presented similar concentrations in indoor and outdoor air. Among the determined VOC, Terpenes and 2-butohxyethanol were shown to be an indoor source, the latter being the indoor pollutant with the highest concentration.
Partitioning Forest‐Floor Respiration into Source Based Emissions in a Boreal Forested Bog: Responses to Experimental Drought
Authors: Munir Tariq , Khadka Bhupesh , Xu Bin , Strack Maria
Published: March 2017

Northern peatlands store globally significant amounts of soil carbon that could be released to the atmosphere under drier conditions induced by climate change. We measured forest floor respiration (RFF) at hummocks and hollows in a treed boreal bog in Alberta, Canada and partitioned the flux into aboveground forest floor autotrophic, belowground forest floor autotrophic, belowground tree respiration, and heterotrophic respiration using a series of clipping and trenching experiments. These fluxes were compared to those measured at sites within the same bog where water‐table (WT) was drawn down for 2 and 12 years. Experimental WT drawdown significantly increased RFF with greater increases at hummocks than hollows. Greater RFF was largely driven by increased autotrophic respiration driven by increased growth of trees and shrubs in response to drier conditions; heterotrophic respiration accounted for a declining proportion of RFF with time since drainage. Heterotrophic respiration was increased at hollows, suggesting that soil carbon may be lost from these sites in response to climate change induced drying. Overall, although WT drawdown increased RFF, the substantial contribution of autotrophic respiration to RFF suggests that peat carbon stocks are unlikely to be rapidly destabilized by drying conditions.
Glass and Process Development for the Next Generation of Optical Fibers: A Review
Authors: Ballato John , Ebendorff-Heidepriem Heike , Zhao Jiangbo , Petit Laeticia , Troles Johann
Published: March 2017

Applications involving optical fibers have grown considerably in recent years with intense levels of research having been focused on the development of not only new generations of optical fiber materials and designs, but also on new processes for their preparation. In this paper, we review the latest developments in advanced materials for optical fibers ranging from silica, to semi-conductors, to particle-containing glasses, to chalcogenides and also in process-related innovations.
Sitting Time, Physical Activity and Sleep by Work Type and Pattern—The Australian Longitudinal Study on Women’s Health
Authors: Clark Bronwyn , Kolbe-Alexander Tracy , Duncan Mitch , Brown Wendy
Published: March 2017

Data from the Australian Longitudinal Study on Women’s Health were used to examine how work was associated with time spent sleeping, sitting and in physical activity (PA), in working women. Young (31–36 years; 2009) and mid-aged (59–64 years; 2010) women reported sleep (categorised as shorter ≤6 h/day and longer ≥8 h/day) and sitting time (work, transport, television, non-work computer, and other; summed for total sitting time) on the most recent work and non-work day; and moderate and vigorous PA (categorised as meeting/not meeting guidelines) in the previous week. Participants reported occupation (manager/professional; clerical/sales; trades/transport/labourer), work hours (part-time; full-time) and work pattern (shift/night; not shift/night). The odds of shorter sleep on work days was higher in both cohorts for women who worked shift or night hours. Longer sitting time on work days, made up primarily of sitting for work, was found for managers/professionals, clerical/sales and full-time workers. In the young cohort, clerical/sales workers and in the mid-aged cohort, full-time workers were less likely to meet PA guidelines. These results suggest multiple behaviour interventions tailored to work patterns and occupational category may be useful to improve the sleep, sitting and activity of working women.
d-Amino Acid Position Influences the Anticancer Activity of Galaxamide Analogs: An Apoptotic Mechanism Study
Authors: Bai Defa , Yu Siming , Zhong Shenghui , Zhao Bingxin , Qiu Shaoling , Chen Jianwei , Lunagariya Jignesh , Liao Xiaojian , Xu Shihai
Published: March 2017

Galaxamide, an extract from Galaxaura filamentosa, is a cyclic pentapeptide containing five l-leucines. Due to the particular cyclic structure and the excellent anticancer activity, synthesis of Galaxamide and its analogs and their subsequent bio-applications have attracted great attention. In the present work, we synthesized six Galaxamide analogs by replacing one of the l-leucines with phenylalanine and varying the d-amino acid position. The anticancer effect of the synthesized Galaxamide analogs was tested against four in vitro human cancer cell lines, human hepatocellular cells (HepG2), human breast cancer cell (MCF-7), human breast adenocarcinoma cells (MDA-MB-435) and a human cervical carcinoma cell line (Hela). Results showed that Galaxamide analogs with different d-amino acid positions displayed distinct anticancer potential. The Galaxamide analog containing d-amino acid at position 5 (Analog-6) presented the strongest anticancer activity. The mechanism study revealed that Analog-6 could cause the early apoptosis of HepG2 cells by inhibiting their growth in the sub-G1 stage of the cell cycle and induce the chromatin condensation and fragmentation, which can be seen as 68% of HepG2 cells inhibited in the sub-G1 stage. Moreover, a mitochondria-mediated pathway was found to be involved in the apoptotic process of Analog-6 on HepG2 cells.
Bimolecular Rate Constants for FAD-Dependent Glucose Dehydrogenase from Aspergillus terreus and Organic Electron Acceptors
Authors: Tsuruoka Nozomu , Sadakane Takuya , Hayashi Rika , Tsujimura Seiya
Published: March 2017

The flavin adenine dinucleotide-dependent glucose dehydrogenase (FAD-GDH) from Aspergillus species require suitable redox mediators to transfer electrons from the enzyme to the electrode surface for the application of bioelectrical devices. Although several mediators for FAD-GDH are already in use, they are still far from optimum in view of potential, kinetics, sustainability, and cost-effectiveness. Herein, we investigated the efficiency of various phenothiazines and quinones in the electrochemical oxidation of FAD-GDH from Aspergillus terreus. At pH 7.0, the logarithm of the bimolecular oxidation rate constants appeared to depend on the redox potentials of all the mediators tested. Notably, the rate constant of each molecule for FAD-GDH was approximately 2.5 orders of magnitude higher than that for glucose oxidase from Aspergillus sp. The results suggest that the electron transfer kinetics is mainly determined by the formal potential of the mediator, the driving force of electron transfer, and the electron transfer distance between the redox active site of the mediator and the FAD, affected by the steric or chemical interactions. Higher k2 values were found for ortho-quinones than for para-quinones in the reactions with FAD-GDH and glucose oxidase, which was likely due to less steric hindrance in the active site in the case of the ortho-quinones.
In-Depth Lipidomic Analysis of Molecular Species of Triacylglycerides, Diacylglycerides, Glycerophospholipids, and Sphingolipids of Buttermilk by GC-MS/FID, HPLC-ELSD, and UPLC-QToF-MS
Authors: Castro-Gómez Pilar , Montero Olimpio , Fontecha Javier
Published: March 2017

Buttermilk, a byproduct of butter manufacturing, has gained considerable attention due to its high concentration of polar lipids as phospho- and sphingolipids from the milk fat globule membrane (MFGM). These polar lipids (PLs) are essential components of all cellular membranes and exert a variety of indispensable metabolic, neurological, and intracellular signaling processes. Despite its importance, there are few research studies that report a comprehensive characterization of the lipid molecular species of MFGM that could contribute to a better understanding of their putative healthful activities. In this study, procedures such as pressurized liquid extraction of polar and nonpolar lipids and their fractionation by flash chromatography have been carried out. The obtained fractions were submitted to an exhaustive characterization from a lipidomic point of view. The characterization includes new data about the identification and quantification of triacylglycerides (TAG), diacylglycerides (DAG), and phospho- and sphingolipids using different chromatographic techniques. The fatty acid profile was comparable to that of the milk fat but with a highly diverse composition of fatty acids. Molecular species have also been determined by using ultra-high performance liquid chromatography/quadruple-time-of-flight mass spectrometry (UPLC/QToF-MS). The TAG (16:0/16:0/6:0) and TAG (16:0/16:0/8:0) were the predominant saturated TAG species and TAG (14:0/18:1/16:0) and TAG (16:0/16:0/18:1) presented the highest content of monounsaturated TAG species. Furthermore; over 30 molecular species of phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), and phosphatidylinositol (PI) could be identified within PL, with PC (16:0/18:1) being the most abundant species. Whereas C16:0 was found to be the preferred FA in TAGs, it was C18:1 in PLs. Several ganglioside species have also been characterized with d18:1 ceramide moiety and secondary acyl chains ranging from C20:0 to C26:1. This approach could broaden the applications of high-resolution mass spectrometry for a better understanding of the role of MFGM and its functionality.
Phosphorus and Iron Deficiencies Influences Rice Shoot Growth in an Oxygen Dependent Manner: Insight from Upland and Lowland Rice
Authors: Mongon Jenjira , Chaiwong Nanthana , Bouain Nadia , Prom-u-thai Chanakan , Secco David , Rouached Hatem
Published: March 2017

Rice is the main staple crop for one-third of the world population. To maximize yields, large quantities and constant input of fertilizers containing essential nutrients such as phosphorus (P) and iron (Fe) are added. Rice can germinate in both aerobic and anaerobic conditions, but the crosstalk between oxygen (O2) and nutrients such as P and Fe on plant growth remains obscure. The aim of this work was to test whether such interactions exist, and, if so, if they are conserved between up- and lowland rice varieties. To do so, we assessed shoot and root biomass as well as inorganic phosphate (Pi) accumulation in four rice varieties, including two lowland rice varieties Nipponbare and Suphanburi 1 (SPR1) (adapted to non-aerated condition) and two upland rice varieties CMU122 and Sew Mae Jun (SMJ) (adapted to aerated condition) under various conditions of Pi and/or Fe deficiencies, in aerated and non-areated solution. Under these different experimental conditions, our results revealed that the altered shoot biomass in Nipponbare and SPR1 was O2-dependent but to a lesser extent in CMU122 and SMJ cultivars. In this perspective, discovering the biological significance and molecular basis of these mineral elements and O2 signal interaction is needed to fully appreciate the performance of plants to multiple environmental changes.
Custom Array Comparative Genomic Hybridization: the Importance of DNA Quality, an Expert Eye, and Variant Validation
Authors: Lantieri Francesca , Malacarne Michela , Gimelli Stefania , Santamaria Giuseppe , Coviello Domenico , Ceccherini Isabella
Published: March 2017

The presence of false positive and false negative results in the Array Comparative Genomic Hybridization (aCGH) design is poorly addressed in literature reports. We took advantage of a custom aCGH recently carried out to analyze its design performance, the use of several Agilent aberrations detection algorithms, and the presence of false results. Our study provides a confirmation that the high density design does not generate more noise than standard designs and, might reach a good resolution. We noticed a not negligible presence of false negative and false positive results in the imbalances call performed by the Agilent software. The Aberration Detection Method 2 (ADM-2) algorithm with a threshold of 6 performed quite well, and the array design proved to be reliable, provided that some additional filters are applied, such as considering only intervals with average absolute log2ratio above 0.3. We also propose an additional filter that takes into account the proportion of probes with log2ratio exceeding suggestive values for gain or loss. In addition, the quality of samples was confirmed to be a crucial parameter. Finally, this work raises the importance of evaluating the samples profiles by eye and the necessity of validating the imbalances detected.
The Effects of Topology on Throughput Capacity of Large Scale Wireless Networks
Authors: Liu Qiuming , Jiang Xuejing , Qiu Xiaohong
Published: March 2017

In this paper, we jointly consider the inhomogeneity and spatial dimension in large scale wireless networks. We study the effects of topology on the throughput capacity. This problem is inherently difﬁcult since it is complex to handle the interference caused by simultaneous transmission. To solve this problem, we, according to the inhomogeneity of topology, divide the transmission into intra-cluster transmission and inter-cluster transmission. For the intra-cluster transmission, a spheroidal percolation model is constructed. The spheroidal percolation model guarantees a constant rate when a power control strategy is adopted. We also propose a cube percolation mode for the inter-cluster transmission. Different from the spheroidal percolation model, a constant transmission rate can be achieved without power control. For both transmissions, we propose a routing scheme with ﬁve phases. By comparing the achievable rate of each phase, we get the rate bottleneck, which is the throughput capacity of the network.
Bee++: An Object-Oriented, Agent-Based Simulator for Honey Bee Colonies
Authors: Betti Matthew , LeClair Josh , Wahl Lindi , Zamir Mair
Published: March 2017

We present a model and associated simulation package (www.beeplusplus.ca) to capture the natural dynamics of a honey bee colony in a spatially-explicit landscape, with temporally-variable, weather-dependent parameters. The simulation tracks bees of different ages and castes, food stores within the colony, pollen and nectar sources and the spatial position of individual foragers outside the hive. We track explicitly the intake of pesticides in individual bees and their ability to metabolize these toxins, such that the impact of sub-lethal doses of pesticides can be explored. Moreover, pathogen populations (in particular, Nosema apis, Nosema cerenae and Varroa mites) have been included in the model and may be introduced at any time or location. The ability to study interactions among pesticides, climate, biodiversity and pathogens in this predictive framework should prove useful to a wide range of researchers studying honey bee populations. To this end, the simulation package is written in open source, object-oriented code (C++) and can be easily modiﬁed by the user. Here, we demonstrate the use of the model by exploring the effects of sub-lethal pesticide exposure on the ﬂight behaviour of foragers.
The Influence of the Composition of Ru100−xAlx (x = 50, 55, 60, 67) Thin Films on Their Thermal Stability
Authors: Seifert Marietta , Rane Gayatri , Oswald Steffen , Menzel Siegfried , Gemming Thomas
Published: March 2017

RuAl thin films possess a high potential as a high temperature stable metallization for surface acoustic wave devices. During the annealing process of the Ru-Al films, Al 2 O 3 is formed at the surface of the films even under high vacuum conditions, so that the composition of a deposited Ru 50 Al 50 film is shifted to a Ru-rich alloy. To compensate for this effect, the Al content is systematically increased during the deposition of the Ru-Al films. Three Al-rich alloys—Ru 45 Al 55 , Ru 40 Al 60 and Ru 33 Al 67 —were analyzed concerning their behavior after high temperature treatment under high vacuum and air conditions in comparison to the initial Ru 50 Al 50 sample. Although the films’ cross sections show a more homogeneous structure in the case of the Al-rich films, the RuAl phase formation is reduced with increasing Al content.
Laser Cladding of Ultra-Thin Nickel-Based Superalloy Sheets
Authors: Gabriel Tobias , Rommel Daniel , Scherm Florian , Gorywoda Marek , Glatzel Uwe
Published: March 2017

Laser cladding is a well-established process to apply coatings on metals. However, on substrates considerably thinner than 1 mm it is only rarely described in the literature. In this work 200 µm thin sheets of nickel-based superalloy 718 are coated with a powder of a cobalt-based alloy, Co–28Cr–9W–1.5Si, by laser cladding. The process window is very narrow, therefore, a precisely controlled Yb fiber laser was used. To minimize the input of energy into the substrate, lines were deposited by setting single overlapping points. In a design of experiments (DoE) study, the process parameters of laser power, laser spot area, step size, exposure time, and solidification time were varied and optimized by examining the clad width, weld penetration, and alloying depth. The microstructure of the samples was investigated by optical microscope (OM) and scanning electron microscopy (SEM), combined with electron backscatter diffraction (EBSD) and energy dispersive X-ray spectroscopy (EDX). Similarly to laser cladding of thicker substrates, the laser power shows the highest influence on the resulting clad. With a higher laser power, the clad width and alloying depth increase, and with a larger laser spot area the weld penetration decreases. If the process parameters are controlled precisely, laser cladding of such thin sheets is manageable.
Improving Tensile and Compressive Properties of an Extruded AZ91 Rod by the Combined Use of Torsion Deformation and Aging Treatment
Authors: Song Bo , Wang Chunpeng , Guo Ning , Pan Hucheng , Xin Renlong
Published: March 2017

In this study, AZ91 magnesium alloy rods were used to investigate the effects of torsion deformation on microstructure and subsequent aging behavior. Extruded AZ91 rod has a uniform microstructure and typical fiber texture. Torsion deformation can generate a gradient microstructure on the cross-section of the rod. After torsion, from the center to the edge in the cross-section of the rod, both stored dislocations and area fraction of {10-12} twins gradually increase, and the basal pole of the texture tends to rotate in the ED direction. Direct aging usually generates coarse discontinuous precipitates and fine continuous precipitates simultaneously. Both twin structures and dislocations via torsion deformation can be effective microstructures for the nucleation of continuous precipitates during subsequent aging. Thus, aging after torsion can promote continuous precipitation and generate gradient precipitation characteristics. Both aging treatment and torsion deformation can reduce yield asymmetry, and torsion deformation enhances the aging hardening effect by promoting continuous precipitation. Therefore, combined use of torsion deformation and aging treatment can effectively enhance the yield strength and almost eliminate the yield asymmetry of the present extruded AZ91 rod. Finally, the relevant mechanisms are discussed.
Microstructural Evolution in AlMgSi Alloys during Solidification under Electromagnetic Stirring
Authors: Mikolajczak Piotr
Published: March 2017

Equiaxed solidification of AlMgSi alloys with Fe and Mn was studied by electromagnetic stirring to understand the effect of forced flow. The specimens solidified with a low cooling rate, low temperature gradient, and forced convection. Stirring induced by a coil system around the specimens caused a transformation from equiaxed dendritic to rosette morphology with minor dendrites and, occasionally, spheroids. This evolution was quantitatively observed with specific surface Sv. The precipitation sequence of the phases was calculated using the CALPHAD (Computer Coupling of Phase Diagrams and Thermochemistry) technique. Melt flow decreased secondary dendrite arm spacing λ2 in the AlSi5Fe1.0 alloy, while λ2 increased slightly in Mg-containing alloys. The length of detrimental β-Al5FeSi phases decreased only in AlSi5Fe1.0 alloy under stirring, whereas in Mg-containing alloys, changes to the β-Al5FeSi phase were negligible; however, in all specimens, the number density increased. The modification of Mn-rich phases, spacing of eutectics, and Mg2Si phases was analyzed. It was found that the occurrence of Mg2Si phase regions reduced fluid flow in the late stages of solidification and, consequentially, reduced shortening of β-Al5FeSi, diminished secondary arm-ripening caused by forced convection, and supported diffusive ripening. However, the Mg2Si phase was found to have not disturbed stirring in the early stage of solidification, and transformation from dendrites to rosettes was unaffected.
A Strategy for Simultaneous Isolation of Less Polar Ginsenosides, Including a Pair of New 20-Methoxyl Isomers, from Flower Buds of Panax ginseng
Authors: Li Sha-Sha , Li Ke-Ke , Xu Fei , Tao Li , Yang Li , Chen Shu-Xiao , Gong Xiao-Jie
Published: March 2017

The present study was designed to simultaneously isolate the less polar ginsenosides from the flower buds of Panax ginseng (FBPG). Five ginsenosides, including a pair of new 20-methoxyl isomers, were extracted from FBPG and purified through a five-step integrated strategy, by combining ultrasonic extraction, Diaion Hp-20 macroporous resin column enrichment, solid phase extraction (SPE), reversed-phase high-performance liquid chromatography (RP-HPLC) analysis and preparation, and nuclear magnetic resonance (NMR) analysis. The quantification of the five ginsenosides was also discussed by a developed method with validations within acceptable limits. Ginsenoside Rg5 showed content of about 1% in FBPG. The results indicated that FBPG might have many different ginsenosides with diverse chemical structures, and the less polar ginsenosides were also important to the quality control and standardization of FBPG.
AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
Authors: Kim Ju-Hyun , Kwon Soon-Sang , Kong Tae , Cheong Jae , Kim Hee , In Moon , Lee Hye
Published: March 2017

AM-2201 is a synthetic cannabinoid that acts as a potent agonist at cannabinoid receptors and its abuse has increased. However, there are no reports of the inhibitory effect of AM-2201 on human cytochrome P450 (CYP) or uridine 5′-diphospho-glucuronosyltransferase (UGT) enzymes. We evaluated the inhibitory effect of AM-2201 on the activities of eight major human CYPs (1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, and 3A4) and six major human UGTs (1A1, 1A3, 1A4, 1A6, 1A9, and 2B7) enzymes in pooled human liver microsomes using liquid chromatography–tandem mass spectrometry to investigate drug interaction potentials of AM-2201. AM-2201 potently inhibited CYP2C9-catalyzed diclofenac 4′-hydroxylation, CYP3A4-catalyzed midazolam 1′-hydroxylation, UGT1A3-catalyzed chenodeoxycholic acid 24-acyl-glucuronidation, and UGT2B7-catalyzed naloxone 3-glucuronidation with IC50 values of 3.9, 4.0, 4.3, and 10.0 μM, respectively, and showed mechanism-based inhibition of CYP2C8-catalyzed amodiaquine N-deethylation with a Ki value of 2.1 μM. It negligibly inhibited CYP1A2, CYP2A6, CYP2B6, CYP2C19, CYP2D6, UGT1A1, UGT1A4, UGT1A6, and UGT1A9 activities at 50 μM in human liver microsomes. These in vitro results indicate that AM-2201 needs to be examined for potential pharmacokinetic drug interactions in vivo due to its potent inhibition of CYP2C8, CYP2C9, CYP3A4, UGT1A3, and UGT2B7 enzyme activities.
Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Polyunsaturated Fatty Acids in a Dose-Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10—A Randomized Placebo-Controlled Trial
Authors: Lefort Natalie , LeBlanc Rémi , Surette Marc
Published: March 2017

Buglossoides arvensis (Ahiflower) oil is a dietary oil rich in stearidonic acid (20% SDA; 18:4 n-3). The present randomized, double blind, placebo-controlled clinical trial investigated the effects of three Ahiflower oil dosages on omega-3 polyunsaturated fatty acid (PUFA) content of plasma and mononuclear cells (MCs) and of the highest Ahiflower dosage on stimulated cytokine production in blood. Healthy subjects (n = 88) consumed 9.7 mL per day for 28 days of 100% high oleic sunflower oil (HOSO); 30% Ahiflower oil (Ahi) + 70% HOSO; 60% Ahi + 40% HOSO; and 100% Ahi. No clinically significant changes in blood and urine chemistries, blood lipid profiles, hepatic and renal function tests nor hematology were measured. Linear mixed models (repeated measures design) probed for differences in time, and time × treatment interactions. Amongst significant changes, plasma and MC eicosapentaenoic acid (EPA, 20:5 n-3) levels increased from baseline at day 28 in all Ahiflower groups (p < 0.05) and the increase was greater in all Ahiflower groups compared to the HOSO control (time × treatment interactions; p < 0.05). Similar results were obtained for α-linolenic acid (ALA, 18:3 n-3), eicosatetraenoic acid (ETA, 20:4 n-3), and docosapentaenoic acid (DPA, 22:5 n-3) content; but not docosahexaenoic acid (DHA, 22:6 n-3). Production of interleukin-10 (IL-10) was increased in the 100% Ahiflower oil group compared to 100% HOSO group (p < 0.05). IL-10 production was also increased in lipopolysaccharide (LPS)-stimulated M2-differentiated THP-1 macrophage-like cells in the presence of 20:4 n-3 or EPA (p < 0.05). Overall; this indicates that the consumption of Ahiflower oil is associated with an anti-inflammatory phenotype in healthy subjects.
Theranostic Value of Multimers: Lessons Learned from Trimerization of Neurotensin Receptor Ligands and Other Targeting Vectors
Authors: Maschauer Simone , Einsiedel Jürgen , Reich Dominik , Hübner Harald , Gmeiner Peter , Wester Hans-Jürgen , Prante Olaf , Notni Johannes
Published: March 2017

Neurotensin receptor 1 (NTS1) is overexpressed on a variety of cancer entities; for example, prostate cancer, ductal pancreatic adenocarcinoma, and breast cancer. Therefore, it represents an interesting target for the diagnosis of these cancers types by positron emission tomography (PET) [...]
Mapping Rice Fields in Urban Shanghai, Southeast China, Using Sentinel-1A and Landsat 8 Datasets
Authors: Mansaray Lamin , Huang Weijiao , Zhang Dongdong , Huang Jingfeng , Li Jun
Published: March 2017

Sentinel-1A and Landsat 8 images have been combined in this study to map rice fields in urban Shanghai, southeast China, during the 2015 growing season. Rice grown in paddies in this area is characterized by wide inter-field variability in addition to being fragmented by other landuses. Improving rice classification accuracy requires the use of multi-source and multi-temporal high resolution data for operational purposes. In this regard, we first exploited the temporal backscatter of rice fields and background land-cover types at the vertical transmitted and vertical received (VV) and vertical transmitted and horizontal received (VH) polarizations of Sentinel-1A. We observed that the temporal backscatter of rice increased sharply at the early stages of growth, as opposed to the relatively uniform temporal backscatter of the other land-cover classes. However, the increase in rice backscatter is more sustained at the VH polarization, and two-class separability measures further indicated the superiority of VH over VV in discriminating rice fields. We have therefore combined the temporal VH images of Sentinel-1A with the normalized difference vegetation index (NDVI) and the modified normalized difference water index (MNDWI) derived from a single-date cloud-free Landsat 8 image. The integration of these optical indices with temporal backscatter eliminated all commission errors in the Rice class and increased overall accuracy by 5.3%, demonstrating the complimentary role of optical indices to microwave data in mapping rice fields in subtropical and urban landscapes such as Shanghai.
A Physical Activity Reference Data-Set Recorded from Older Adults Using Body-Worn Inertial Sensors and Video Technology—The ADAPT Study Data-Set
Authors: Bourke Alan , Ihlen Espen , Bergquist Ronny , Wik Per , Vereijken Beatrix , Helbostad Jorunn
Published: March 2017

Physical activity monitoring algorithms are often developed using conditions that do not represent real-life activities, not developed using the target population, or not labelled to a high enough resolution to capture the true detail of human movement. We have designed a semi-structured supervised laboratory-based activity protocol and an unsupervised free-living activity protocol and recorded 20 older adults performing both protocols while wearing up to 12 body-worn sensors. Subjects’ movements were recorded using synchronised cameras (≥25 fps), both deployed in a laboratory environment to capture the in-lab portion of the protocol and a body-worn camera for out-of-lab activities. Video labelling of the subjects’ movements was performed by five raters using 11 different category labels. The overall level of agreement was high (percentage of agreement >90.05%, and Cohen’s Kappa, corrected kappa, Krippendorff’s alpha and Fleiss’ kappa >0.86). A total of 43.92 h of activities were recorded, including 9.52 h of in-lab and 34.41 h of out-of-lab activities. A total of 88.37% and 152.01% of planned transitions were recorded during the in-lab and out-of-lab scenarios, respectively. This study has produced the most detailed dataset to date of inertial sensor data, synchronised with high frame-rate (≥25 fps) video labelled data recorded in a free-living environment from older adults living independently. This dataset is suitable for validation of existing activity classification systems and development of new activity classification algorithms.
An Optically Pumped Magnetometer Working in the Light-Shift Dispersed Mz Mode
Authors: Schultze Volkmar , Schillig Bastian , IJsselsteijn Rob , Scholtes Theo , Woetzel Stefan , Stolz Ronny
Published: March 2017

We present an optically pumped magnetometer working in a new operational mode—the light-shift dispersed Mz (LSD-Mz) mode. It is realized combining various features; (1) high power off-resonant optical pumping; (2) Mz configuration, where pumping light and magnetic field of interest are oriented parallel to each other; (3) use of small alkali metal vapor cells of identical properties in integrated array structures, where two such cells are pumped by circularly polarized light of opposite helicity; and (4) subtraction of the Mz signals of these two cells. The LSD-Mz magnetometer’s performance depends on the inherent and very complex interplay of input parameters. In order to find the configuration of optimal magnetometer resolution, a sensitivity analysis of the input parameters by means of Latin Hypercube Sampling was carried out. The resulting datasets of the multi-dimensional parameter space exploration were assessed by a subsequent physically reasonable interpretation. Finally, the best shot-noise limited magnetic field resolution was determined within that parameter space. As the result, using two 50 mm3 integrated vapor cells a magnetic ﬁeld resolution below 10 fT/√Hz at Earth’s magnetic ﬁeld strength is possible.