bluuebunny/crossref_metadata_2025 huggingface dataset:
SUSTAINABLE SUPPLY CHAIN MANAGEMENT IN CONSTRUCTION
Authors: Cataldo Ieva
Published: January 2022

Most of the existing supply chain management methods and systems are being transferred to construction sphere regardless of the specifics of companies in the construction sector. Numerous complex factors such as ecological, social and economic are required for the continuous evaluation in the modern management of construction sector. The provided studies and the research to examine sustainable supply chain management in construction sector from a holistic perspective, concentrating on mostly longterm sustainable decision­making by the construction company rather than being centered only on the supply chain management for construction projects. This paper identifies a list of sustainability indicators for examining the supply chains of construction companies. Those indicators were categorized and assigned to one or a couple groups by reviewing their use in the previous literature agreeing to the reasoning to way better reflect the SSCM principle of their use in construction companies. The use of indicators can help develop strategies for the construction sector for sustainable policy makers and construction company managers.
INTERNATIONAL AND REGIONAL CAPITAL MOBILITY IN LATIN AMERICAN COUNTRIES
Authors: Yersh Valeryia
Published: January 2022

This study examines the role of global, regional and domestic saving for domestic investment financing in the panel of Latin American and Caribbean countries along with its three regional integration blocks, namely SICA, Andean Community and MERCOSUR. Panel regression and rolling-window estimation results reveal that global saving is the main source of domestic investment financing in the region of Latin America and the Caribbean, SICA, Andean Community and MERCOSUR. The role of domestic and regional savings is rather limited, implying that there are weak regional and domestic channels that can funnel domestic and regional savings into investment in the analysed samples. The importance of regional agreement saving is insignificant and decreases over the analysed period except for the Andean Community. The results indicate low financial integration of the member-countries within the three regional trade agreements.
Hypermnesia and Amnesia: Remembering (with) the Body and Post-Conflict Memorials and Architectures
Authors: Borsari Andrea , Leoni Giovanni
Published: January 2022

The article consists of two parts. The first part (§§ 1–2) investigates the indiscriminate and absolute remembering and forgetting of everything, hypermnesia and amnesia as the extreme terms that research has used and uses for the different phenomena of memory, both in individuals and in social and political forms. In the face of these shifts it is thus indispensable to re-establish a critique of the paradoxical effects of memory aids and, at the same time, to seek new forms of remembrance that by mixing an experiential dimension and public sphere refocus the attention on the connection between latency, tension and experiential triggers of involuntary memory and on the ability to break through the fictions of collective memory. On this basis, the second part of the article (§§ 3–4) analyses how the experience of political and racial deportation during World War II drastically changed the idea of memorial architecture. More specifically, the analysis deals with a kind of memorial device that must represent and memorialise persons whose bodies have been deliberately cancelled. The aim is to present and analyse the artistic and architectonic efforts to refer to those forgotten bodies, on the one hand, and on the other hand to point out how for these new kind of memorials the body of the visitor is asked to participate, both physically and emotionally, in this somehow paradoxical search for lost bodies, offering oneself as a substitute.
Entanglements of art and memory activism in Hungary’s illiberal democracy
Authors: Deim Reka
Published: January 2022

This paper explores how art contributes to the articulation of memories that counter the official historical narrative of Hungary’s self-proclaimed political and ideological system, illiberal democracy. Amid deepening polarization between Europe’s post-colonialist and post-socialist countries, the Hungarian government promotes a Christian conservative national identity against the “liberal” values of Western Europe. Systematic appropriation of historical traumas is at the core of such efforts, which largely manifests in removing, erecting and reinstating memorials, as well as in the re-signification of trauma sites. Insufficient civic involvement in rewriting histories generates new ways of resistance, which I demonstrate through the case study of a protest-performance organized by the Living Memorial activist group as a response to the government’s decision to displace the memorial of Imre Nagy in 2018. I seek to understand the dynamics between top-down memory politics, civil resistance and art within the conceptual apparatus of the “memory activism nexus” (Rigney 2018, 2020) and “multidirectional memories” (Rothberg 2009). I argue that artistic memory activism has limited potential to transform the dynamics of memory in a context where a national conservative political force has gradually taken control over historical narratives, triggering inevitably polarizing responses in the society. Although profoundly embedded in local histories, the case-study may offer new ways of negotiating traumatic heritages through the entanglement of art and memory activism.
Memory, art and intergenerational transmission. Artistic practices with young people in memory sites in Argentina
Authors: Tornay Lizel , Alvarez Victoria , Sanchis Fabricio Laino , Paganini Mariana
Published: January 2022

This text analyzes recent experiences with young people from Middle Schools of the city of Buenos Aires (Argentina) in Memory Sites of this city. Our inquiry is interested in the intergenerational transmission referring to the traumatic past around the last military dictatorship established in Argentina between 1976 and 1983. With this interest, two experiences designed through artistic languages are analyzed: the Posters Project from the Memory Park and the use of poetry in the guided visits to the Memory Site at "El Olimpo", former Clandestine Detention Center for Torture and Extermination, both spaces of the city of Buenos Aires.
Constant consensus building: art and conflict in the ESMA museum and site of memory
Authors: Naftal Alejandra
Published: January 2022

This article describes the history, development and social role of the ESMA Museum and Site of Memory, which is located on the grounds of the former clandestine centre for detention, torture and extermination, in the intergenerational transmission of traumatic memories of the Argentinian dictatorship. The project is characterised by the cumulative effort of artistic expression, public debate, conflict and tension. Through the presentation of different artistic installations and plays, the article explains the focal function of art practices in spaces of memory that are strongly linked to a traumatic past, as well as how undertaking these practices can lead to the establishment of consensus.
Taxonomy and phylogeny of the novel rhytidhysteron-like collections in the Greater Mekong Subregion
Authors: Ren Guang-Cong , Wanasinghe Dhanushka N. , Jeewon Rajesh , Monkai Jutamart , Mortimer Peter E. , Hyde Kevin D. , Xu Jian-Chu , Gui Heng
Published: January 2022

During our survey into the diversity of woody litter fungi across the Greater Mekong Subregion, three rhytidhysteron-like taxa were collected from dead woody twigs in China and Thailand. These were further investigated based on morphological observations and multi-gene phylogenetic analyses of a combined DNA data matrix containing SSU, LSU, ITS, and tef1-α sequence data. A new species of Rhytidhysteron, R. xiaokongense sp. nov. is introduced with its asexual morph, and it is characterized by semi-immersed, subglobose to ampulliform conidiomata, dark brown, oblong to ellipsoidal, 1-septate, conidia, which are granular in appearance when mature. In addition to the new species, two new records from Thailand are reported viz. Rhytidhysteron tectonae on woody litter of Betula sp. (Betulaceae) and Fabaceae sp. and Rhytidhysteron neorufulum on woody litter of Tectona grandis (Lamiaceae). Morphological descriptions, illustrations, taxonomic notes and phylogenetic analyses are provided for all entries.
Three new Xylaria species (Xylariaceae, Xylariales) on fallen leaves from Hainan Tropical Rainforest National Park
Authors: Pan Xiao-Yan , Song Zi-Kun , Qu Zhi , Liu Tie-Dong , Ma Hai-Xia
Published: January 2022

Three new species of Xylaria on fallen leaves in Hainan Province of China are described and illustrated, based on morphological and molecular evidence. Xylaria hedyosmicola is found on fallen leaves of Hedyosmum orientale and featured by thread-like stromata with a long sterile filiform apex. Phylogenetically, X. hedyosmicola is closely related to an undescribed Xylaria sp. from Hawaii Island, USA and morphologically similar to X. vagans. Xylaria lindericola is found on fallen leaves of Lindera robusta and characterised by its subglobose stromata and a long filiform stipe. It is phylogenetically closely related to X. sicula f. major. Xylaria polysporicola is found on fallen leaves of Polyspora hainanensis, it is distinguished by upright or prostrate stromata and ascospores sometimes with a slimy sheath or non-cellular appendages. Xylaria polysporicola is phylogenetically closely related to X. amphithele and X. ficicola. An identification key to the ten species on fallen leaves in China is given.
The current status and outcomes of in-hospital P2Y12 receptor inhibitor switching in Korean patients with acute myocardial infarction
Authors: Park Keun-Ho , Jeong Myung Ho , Kim Hyun Kuk , Ki Young-Jae , Kim Sung Soo , Ahn Youngkeun , Kook Hyun Yi , Kim Hyo-Soo , Gwon Hyeon Cheol , Seung Ki Bae , Rha Seung Woon , Chae Shung Chull , Kim Chong Jin , Cha Kwang Soo , Park Jong Seon , Yoon Jung Han , Chae Jei Keon , Joo Seung Jae , Choi Dong-Joo , Hur Seung Ho , Seong In Whan , Cho Myeong Chan , Kim Doo Il , Oh Seok Kyu , Ahn Tae Hoon , Hwang Jin Yong ,   on behalf of the KAMIR-NIH registry investigators
Published: January 2022

Background/Aims: While switching strategies of P2Y12 receptor inhibitors (RIs) have sometimes been used in acute myocardial infarction (AMI) patients, the current status of in-hospital P2Y12RI switching remains unknown.Methods: Overall, 8,476 AMI patients who underwent successful revascularization from Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) were divided according to in-hospital P2Y12RI strategies, and net adverse cardiovascular events (NACEs), defined as a composite of cardiac death, non-fatal myocardial infarction (MI), stroke, or thrombolysis in myocardial infarction (TIMI) major bleeding during hospitalization were compared.Results: Patients with in-hospital P2Y12RI switching accounted for 16.5%, of which 867 patients were switched from clopidogrel to potent P2Y12RI (C-P) and 532 patients from potent P2Y12RI to clopidogrel (P-C). There were no differences in NACEs among the unchanged clopidogrel, the unchanged potent P2Y12RIs, and the P2Y12RI switching groups. However, compared to the unchanged clopidogrel group, the C-P group had a higher incidence of non-fatal MI, and the P-C group had a higher incidence of TIMI major bleeding. In clinical events of in-hospital P2Y12RI switching, 90.9% of non-fatal MI occurred during pre-switching clopidogrel administration, 60.7% of TIMI major bleeding was related to pre-switching P2Y12RIs, and 71.4% of TIMI major bleeding was related to potent P2Y12RIs. Only 21.6% of the P2Y12RI switching group switched to P2Y12RIs after a loading dose (LD); however, there were no differences in clinical events between patients with and without LD.Conclusions: In-hospital P2Y12RI switching occurred occasionally, but had relatively similar clinical outcomes compared to unchanged P2Y12RIs in Korean AMI patients. Non-fatal MI and bleeding appeared to be mainly related to pre-switching P2Y12RIs.
Version française du Postpartum Bonding Questionnaire
Authors: Demanche Aude , Michel Lise , Chabbert Margaux , Wendland Jaqueline
Published: January 2022

Le but de cette étude était d’examiner les qualités psychométriques de la version française du Postpartum Bonding Questionnaire et de valider cet outil pour la population française. Dans ce but, deux études successives ont été réalisées sur un total de 1 637 mères recrutées en maternité et sur des forums de parentalité en ligne. La structure factorielle, la consistance interne, la fiabilité test-retest, la sensibilité, la spécificité ainsi que la validité convergente avec les symptômes de dépression (EPDS), d’anxiété-état (STAI-Y-A) et les scores de bonding évalués avec l’échelle MIBS ont été étudiés. La structure originale à quatre facteurs n’a pas été retrouvée. Une nouvelle organisation à une dimension, composée de 22 items, est apparue. Les analyses ont montré des qualités psychométriques satisfaisantes. Le PBQ apparaît comme un outil valide et fiable pour dépister les troubles précoces du lien mère-enfant dans la population française.
L’Élysée, lieu de décision
Authors: Mignon Emmanuelle
Published: January 2022

Depuis 1958, le président de la République exerce un rôle central dans la conduite des affaires de l’État, et toutes les réformes constitutionnelles intervenues n’ont fait qu’accroître cette emprise. Or, paradoxalement, loin de se moderniser et de se professionnaliser, comme ce fut le cas du processus décisionnel du gouvernement à partir de la Première Guerre mondiale, celui de l’Élysée est resté informel et désordonné. Si la souplesse et la rapidité sont une contrepartie avantageuse de cette inorganisation, les inconvénients nous semblent l’emporter.
Les archives de l’Élysée
Authors: Touzeau-Mouflard Line
Published: January 2022

Le droit d’accès aux archives est garanti constitutionnellement. Les archives de l’Élysée devraient voir leur régime aligné sur les archives publiques, leur accessibilité assurant l’exercice d’un droit à l’information et d’un contrôle citoyen. L’article expose le régime dérogatoire des archives des anciens présidents, à qui est concédé le pouvoir de décider de l’ouverture ou de la fermeture de ce qui constitue, pour un temps, « leurs » archives.
Le problème du schématisme transcendantal : son rôle dans l’évolution de la théorie kantienne des facultés
Authors: Beydoun Zaki
Published: January 2022

Le problème du schématisme transcendantal est le moment de la Critique de la raison pure où la question de la signification des catégories pousse Kant à remettre en question l’indépendance de l’imagination productive et de l’intuition à l’égard de l’entendement, position que la première rédaction de la Déduction transcendantale partageait encore avec « L’esthétique transcendantale » et la Dissertation de 1770 . Ce revirement devient plus explicite et résolu dans la seconde rédaction de la Déduction transcendantale, sans que l’imagination productive, la faculté des intuitions pures, se trouve pour autant réduite à une fonction de l’entendement : si « la synthèse transcendantale de l’imagination » est « un effet de l’entendement sur la sensibilité » selon cette rédaction ( KRV , B 152), c’est parce qu’elle résulte de la détermination a priori , par ce dernier, de certaines activités représentatives pré-conceptuelles dont Kant reconnaît la présence dans la sensibilité animale.
Racial Differences in Orthopedic Trauma Surgery
Authors: Suneja Nishant , Kong Ryan M. , Tiburzi Hallie A. , Shah Neil V. , von Keudell Arvind G. , Harris Mitchel B. , Saleh Ahmed
Published: January 2022

Racial discrepancies among patients in the United States undergoing orthopedic trauma surgery have not been investigated. Issues relating to socioeconomic status and access to care have played a role in the health outcomes of racial groups. In orthopedic surgery, recent joint arthroplasty literature has shown significant racial differences in the use of elective joint arthroplasty. Furthermore, studies also suggest increased rates of early complication in racial minority groups. In general, little information exists on the postoperative outcomes of racial minority groups in orthopedic surgery. We retrospectively queried the National Surgical Quality Improvement Program database to identify patients undergoing orthopedic trauma surgery between 2008 and 2016. Patients of all ages who underwent orthopedic trauma surgery were identified using
Current Procedural Terminology
codes. Patients classified as either Black or White were included in the study. Demographic data, comorbidities, and basic surgical data were compared between the groups. Adverse outcomes in the initial 30 days postoperative were also examined. Higher frequencies of deep wound infection (0.5% vs 0.3%,
P
=.002) were noted among Black patients, with decreased mortality (0.3% vs 0.6%,
P
=.004) and postoperative transfusion (2.7% vs 3.8%,
P
<.001) rates, compared with White patients. Clear differences exist in the demographic, surgical, and outcome data between Black and White patients undergoing orthopedic trauma surgery. More epidemiological studies are required to further investigate racial differences in orthopedic trauma surgery. [
Orthopedics
. 2022;45(2):71–76.]
Glomus Tumors of the Distal Phalanx: A Retrospective Review of Clinical Diagnosis and Treatment
Authors: Ge Jianhua , Zhang Dechou , Xue Zhaolong , Lu MengJie , Yin Yiran , Lu Xiaobo
Published: January 2022

Glomus tumors (GTs) are rare and typically occur in distal digital bones, with a majority of cases comprising benign vascular tumors. The current study retrospectively reviewed 10 cases of GTs treated by the authors between January 2009 and December 2016. In 9 cases, the GTs were subungual; 1 case was periungual. The affected fingers included 2 thumbs, 3 index fingers, 3 middle fingers, and 2 little fingers. The GTs showed characteristic signs and symptoms. All patients underwent tumor excision. Pathological examination found a thin layer of fibrous membrane surrounding the excised tumor body, which contained small vessels surrounded by multilayered tumor cells. No recurrence was seen during follow-up. The results of this study suggested the following: (1) whole tumor excision is key to preventing GT recurrence; and (2) in case of considerable phalangeal cortex erosion, K-wire fixation followed by autogenous bone grafting can produce satisfactory outcomes, although accurate evidence-based indications for this management need to be established. [
Orthopedics
. 2022;45(2):e101–e106.]
Comparison of Lesser Toe Proximal Interphalangeal Joint Arthrodesis Versus Resection Arthroplasty: A Randomized Controlled Study
Authors: Scheidt Sebastian , Nowak Victoria , Mittag Falk , Götze Marco , Wülker Nikolaus , Hofmann Ulf Krister
Published: January 2022

The goal of this study was to compare operative outcomes after lesser toe deformity correction with either proximal interphalangeal (PIP) joint arthrodesis or PIP joint resection arthroplasty. A prospective randomized controlled trial was performed with 37 patients (48 toes) operated on with one of these two procedures. Evaluation of the numeric rating scale score, the American Orthopedic Foot and Ankle Society score, osseous consolidation, and clinical outcome was performed preoperatively and at 6 weeks and 6 months postoperatively. Both study groups showed significant improvement at 6 months postoperatively. Although osseous consolidation was significantly higher for the arthrodesis group (
P
=.001), this difference did not affect clinical outcomes, and at 6 months postoperatively, pain on the numeric rating scale was 0 (range, 0–7) for the arthroplasty group and 0 (range, 0–5) for the arthrodesis group (
P
=.669). The American Orthopedic Foot and Ankle Society score was 83 (range, 39–95) and 80 (range, 59–95), respectively (
P
=.879). No difference was observed for signs of inflammation or axis correction. Even a direct comparison of toes with radiologically osseous fusion (n=16) with those without fusion (n=32) did not show any clinical differences. This randomized controlled study showed no clinical differences in outcome between PIP joint arthrodesis and PIP joint resection arthroplasty for correction of lesser toe deformities, with good to excellent outcomes for both groups. [
Orthopedics
. 2022;45(2):86–90.]
Recommendation of Surgery and Other Interventions Is Associated With Increased Patient Satisfaction With Orthopedic Outpatient Visits
Authors: Stephens Andrew R. , Steadman Jesse N. , Kazmers Nikolas H.
Published: January 2022

The primary goal of our study was to determine whether satisfaction with orthopedic surgery outpatient visits is affected by a recommendation for surgery compared with a recommendation for nonoperative treatment, as measured by the Press Ganey Outpatient Medical Practice Survey (PGOMPS). Secondarily, we evaluated the effect of offering an injection, therapy, or any intervention (surgery, injection, therapy, immobilization, aspiration, or radiation therapy) on PGOMPS scores. To investigate this relationship, we reviewed new orthopedic outpatient visits at a tertiary academic center during a single year (2018). Patient satisfaction was defined as a PGOMPS score greater than the 33rd percentile. Univariate and multivariate binary logistic regression was conducted to determine the effect of a surgical recommendation and the effect of recommending an injection, therapy, or any intervention on the PGOMPS total score and provider subscore. Of the 1217 included patients, multivariate analysis showed that a surgical recommendation was significantly and independently associated with satisfaction on the PGOMPS total score and provider subscore. Multivariate analysis also showed that being offered an injection, therapy, or any intervention was significantly associated with higher PGOMPS total scores compared with not being offered those interventions. Patients who were offered surgery or other interventions were significantly more likely to be satisfied with their encounter and the surgeon. Patients who were offered surgery were significantly more likely to be satisfied with their encounter and the surgeon than those who were not offered surgery. Additionally, patients who were offered any intervention were significantly more likely to be satisfied with their encounter than those who were not offered an intervention. [
Orthopedics
. 2022;45(3):187–191.]
Comparison of the Cost-Effectiveness of SMILE, FS-LASIK, and PRK for Myopia in a Private Eye Center in Spain
Authors: Balgos Marie Joan Therese D. , Piñero David P. , Canto-Cerdan Mario , Alió del Barrio Jorge L. , Alió Jorge L.
Published: January 2022

PURPOSE:

To describe and compare the cost-effectiveness of small incision lenticule extraction (SMILE), femtosecond laser–assisted in situ keratomileusis (FS-LASIK), and photorefractive keratectomy (PRK) for treating myopia and myopic astigmatism in a private eye center.

METHODS:

The perspectives for this cost-effectiveness analysis were for the payer and the health care sector. For the payer's perspective, a decision tree model was made, with a time period of 30 years, and the average weighted utility values and quality-adjusted life years (QALY) were computed for each procedure. The average weighted costs were derived for each procedure and divided by the QALY to obtain the incremental cost-effectiveness ratios (ICER). For the health care sector's perspective, the direct and indirect costs of acquiring the equipment and maintaining the facilities—including consumables and personnel salaries—were obtained to compute the minimum number of patients treated per year.

RESULTS:

The weighted utility values were 0.8 for SMILE and PRK and 0.77 for FS-LASIK. The weighted QALYs were 24 for SMILE and PRK, and 23.1 for FS-LASIK. The average weighted costs were 335.45, 443, and 346.96€, respectively. The resulting incremental cost-effectiveness ratios were 13.98 €/QALY for SMILE, 18.46 €/QALY for PRK, and 15.02 €/QALY for FS-LASIK. There was a negative correlation between the ICER and the time (in years) after the surgery. To achieve a profit, the minimum number of patients treated per year is 155 for SMILE, 136 for PRK, and 155 for FS-LASIK.

CONCLUSIONS:

Laser corneal refractive surgery is cost-effective for a person desirous of refractive correction for myopia. SMILE had the lowest ICER, followed by FS-LASIK and PRK. This trend was noted at all time periods. The cost of investing in laser refractive surgery facilities is outweighed by the potential income in high-volume eye centers.

[
J Refract Surg
. 2022;38(1):21–26.]
Epithelial Basement Membrane Regeneration After PRK-Induced Epithelial-Stromal Injury in Rabbits: Fibrotic Versus Non-fibrotic Corneal Healing
Authors: de Oliveira Rodrigo Carlos , Sampaio Lycia Pedral , Shiju Thomas Michael , Santhiago Marcony R. , Wilson Steven E.
Published: January 2022

PURPOSE:

To study epithelial basement membrane (EBM) regeneration in non-fibrotic and fibrotic corneas after photorefractive keratectomy (PRK).

METHODS:

Rabbits (120 total) had either epithelial scrape alone, −4.50 diopters (D) PRK, −9.00 D PRK, or no surgery. Immunohistochemistry was performed on cryofixed corneas at time points from unwounded to 8 weeks (four corneas at each time point in each group). Multiplex immunohistochemistry was performed for EBM components, including collagen type IV, laminin beta-3, laminin alpha-5, perlecan, and nidogen-1. Stromal cellular composition was studied by triplex immunohistochemistry for keratocan, vimentin, and alpha-smooth muscle actin (SMA).

RESULTS:

PRK-injured EBM significantly regenerated by 4 days after surgery. However, early TGF-beta–regulating perlecan incorporation into the nascent EBM declined 4 to 7 days after surgery in fibrotic corneas. Non-fibrotic corneas that had fully regenerated EBM (with all five components incorporated into the EBM) were transparent and had few SMA-positive myofibroblasts in the stroma. Conversely, corneas with defective nascent EBM that lacked perlecan developed many anterior stromal myofibroblasts and fibrosis at 3 to 4 weeks after surgery and had large amounts of collagen type IV in the nascent EBM and anterior stroma. Myofibroblasts synthesized perlecan but were incompetent to incorporate the heparin sulfate proteoglycan into the nascent EBM. Corneal transparency was restored over several months even in fibrotic corneas, and this was associated with a return of EBM perlecan, myofibroblast disappearance, and reabsorption of disordered extracellular matrix.

CONCLUSIONS:

Defective incorporation of perlecan into the regenerating EBM by subepithelial myofibroblasts, and likely their precursor cells, underlies the development and persistence of stromal fibrosis after PRK corneal injury.

[
J Refract Surg
. 2022;38(1):50–60.]
Recurrence and Visual Outcomes of Phototherapeutic Keratectomy in Lattice Corneal Dystrophy: A Cohort Study
Authors: Sauvageot Paola , Julio Gemma , Bolaños Jennifer V. , Carrera Marta , de Toledo Juan Álvarez , Barraquer Rafael Ignacio
Published: January 2022

PURPOSE:

To evaluate recurrence and visual outcomes of phototherapeutic keratectomy (PTK) in lattice corneal dystrophy.

METHODS:

Kaplan-Meier survival analyses were retrospectively performed. Recurrence was defined as central biomicroscopic findings of recurrence with decreased visual acuity: loss of at least two lines or visual acuity ≤ 20/40) at any time during the follow-up.

RESULTS:

Twenty-two virgin eyes and 10 with previous keratoplasty (20 patients; 13 women and 7 men) were studied during a mean of 4.7 ± 3.5 years (range: 11 months to 18 years). One and 5 years after the first PTK (PTK1), 1 of 32 and 12 of 32 eyes, respectively, recurred. The cumulative probabilities of recurrence were 3%, 48%, and 89% in the whole sample at 1, 5, and 10 years, respectively. All cases in the virgin group and 8 eyes in the previous keratoplasty group improved their visual acuity. There were no significant differences in recurrence probability between groups (log-rank test;
P
= .86). A second PTK (PTK2) was performed in 15 of 32 eyes, with 6 postoperative recurrences recorded. The cumulative probabilities of recurrence in the whole sample were 18%, 30%, and 44% at 1, 3, and 5 years, respectively. Visual acuity improved in 11 of 13 eyes in the virgin group and 2 of 2 eyes in the previous keratoplasty group. Recurrence probability after PTK1 and PTK2 was similar in the whole sample (log-rank test;
P
= .637). Persistent graft edema after PTK1 in one eye was the only complication found.

CONCLUSIONS:

PTK can be an effective, safe, and repeatable treatment to delay keratoplasty in symptomatic lattice corneal dystrophy.

[
J Refract Surg
. 2022;38(1):43–49.]
Visual Acuity, Wavefront Aberrations, and Defocus Curves With an Enhanced Monofocal and a Monofocal Intraocular Lens: A Prospective, Randomized Study
Authors: Nanavaty Mayank A. , Ashena Zahra , Gallagher Sean , Borkum Steven , Frattaroli Paul , Barbon Emma
Published: January 2022

PURPOSE:

To compare uniocular and binocular visual acuity, wavefront aberrations, and defocus curves using the TECNIS Eyhance (Johnson & Johnson) and RayOne (Rayner) intraocular lenses (IOLs).

METHODS:

In this prospective, randomized, comparative study, 50 patients (100 eyes) were randomized to receive the same IOL bilaterally (
ClinicalTrials.gov
Identifier: NCT04175951). Follow-up visits were at 1 and 3 to 9 months postoperatively. Primary outcome measures were uncorrected distance (UDVA) and uncorrected intermediate (UIVA) visual acuity (logMAR) at 66 cm. Secondary outcome measures were corrected distance (CDVA) and distance-corrected intermediate (DCIVA) visual acuity at 66 cm, manifest refraction, spherical (Z
4
0
) and vertical coma (Z
3
−1
) aberrations (total, internal eye, and corneal) at normal pupil size, defocus curves, and Catquest 9SF and Glare and Halos questionnaire on Likert scale (1 = no glare and halos and 4 = continuous).

RESULTS:

Uniocular UDVA (
P
= .02), UIVA (
P
= .02), and binocular UIVA (
P
< .01) and uniocular (
P
= .01) and binocular (
P
< .01) DCIVA were better with the TECNIS Eyhance IOL at 3 to 9 months. At 3 to 9 months, both uniocular and binocular defocus curves were significantly broader with the TECNIS Eyhance IOL between −0.50 and −3.00 diopters (D). For total and internal eye, there was a statistically but clinically insignificant difference in Z
4
0
with the TECNIS Eyhance IOL. Rasch scores improved (TECNIS Eyhance: 2.04 ± 1.34 to 2.91 ± 0.81 and RayOne:1.61 ± 1.35 to 2.97 ± 0.16) at 3 to 9 months. Refraction, Z
3
−1
, glare, and halos were not different.

CONCLUSIONS:

The TECNIS Eyhance IOL provided better DCIVA and broader defocus curves than the RayOne IOL. There was no difference in CDVA or patient-reported outcomes. Although there were some differences in aberrations when measured with normal pupil size, they were not clinically significant.

[
J Refract Surg
. 2022;38(1):10–20.]
Laboratory and Clinical Experience With a Diffractive Trifocal Intraocular Lens Sutured to an Artificial Iris
Authors: Mayer Christian S. , Son Hyeck-Soo , Łabuz Grzegorz , Baur Isabella D. , Yildirim Timur M. , Auffarth Gerd U. , Khoramnia Ramin
Published: January 2022

PURPOSE:

To determine in vitro, using a translational research approach before realizing the procedure in a patient with iatrogenic aphakia and partial aniridia, whether suturing a trifocal intraocular lens (IOL) to an artificial iris degrades the IOL's optical quality.

METHODS:

Optical quality was analyzed by measuring the modulation transfer function (MTF) at a 3-mm aperture and at 50 and 100 lp/mm spatial frequencies. The FineVision Pod F GF IOL (PhysIOL) was assessed in two powers: two +20.00 diopters (D) (20A and 20B IOLs) and two +30.00 D (30A and 30B IOLs). The IOLs' decentration in relation to the artificial iris's center was evaluated. The laboratory results provided empirical evidence in the informed consent for surgical intervention in a patient with iatrogenic aphakia and iris defect in one eye. Clinical results were measured using the parameter of corrected distance visual acuity plus a patient self-assessment of the cosmetic appearance of the operated eye.

RESULTS:

The 20A and 20B IOLs demonstrated a mean MTF reduction of up to 1.1%, whereas the 30A and 30B IOLs showed a decrease of up to 5.2% for both spatial frequencies. All lenses showed good centration levels. In the clinical case, the patient showed corrected distance visual acuity, distance-corrected near visual acuity, and distance-corrected intermediate visual acuity of 0.20, 0.20, and 0.22 logMAR, respectively. The patient was satisfied with the cosmetic outcome.

CONCLUSIONS:

There was merely a slight reduction in trifocal IOL optical quality after it was sutured to an artificial iris. Clinically, the combined implantation of the artificial iris and FineVision IOL provided good functional and cosmetic outcomes.

[
J Refract Surg
. 2022;38(1):61–68.]
A review of fuel additives' effects and predictions on internal combustion engine performance and emissions
Authors: Daud Sarbani , Hamidi Mohd Adnin , Mamat Rizalman
Published: January 2022

In recent years, there has been an increasing interest in additives for fuel research in the field of internal-combustion engines. Many studies have been conducted to improve the performance and emissions of the engine. Many kinds of additives in the form of solids, liquids, and gases have been used. The objective of this review is to examine the effects of having additives on the performance and emissions of an internal combustion engine. Additives such as alcohol, hydrogen, and metal oxides are proven to be successful in improving performance or reducing emissions. Results from selected papers are discussed and summarised in a table. With the new developments in nanotechnology, many researchers have shown an increased interest in carbon-based nanoparticles such as multi-walled carbon nanotubes (MWCNT) and single-walled carbon nanotubes (SWCNT). Lately, with the discovery of graphene production techniques, graphene nanoplatelets (GNP) have also been applied as fuel additives. In addition to understanding the effects of the additives on the engine performance and emissions, researchers extended the research to predict the outcome of the performance and emissions. The experiments involving the predictions efforts are summarised in a table. From the summary, it is found that the prediction of the GNP as fuel additive effects to the performance and emissions has not yet been explored. This gap is an opportunity for researchers to explore further.
Modeling student engagement using optimal control theory
Authors: Lewis Debra
Published: January 2022

Student engagement in learning a prescribed body of knowledge can be modeled using optimal control theory, with a scalar state variable representing mastery, or self-perceived mastery, of the material and control representing the instantaneous cognitive effort devoted to the learning task. The relevant costs include emotional and external penalties for incomplete mastery, reduced availability of cognitive resources for other activities, and psychological stresses related to engagement with the learning task. Application of Pontryagin's maximum principle to some simple models of engagement yields solutions of the synthesis problem mimicking familiar behaviors including avoidance, procrastination, and increasing commitment in response to increasing mastery.
Complex intuitionistic fuzzy soft SWARA - COPRAS approach: An application of ERP software selection
Authors: Garg Harish ,   School of Mathematics, Thapar Institute of Engineering & Technology, Deemed University Patiala -147004, Punjab, India, Vimala J. , Rajareega S. , Preethi D. , Perez-Dominguez Luis ,   Department of Mathematics, Alagappa University, Karaikudi, Tamilnadu, India,   Departamento de Ingenieria Industrial y Manufactura, Universidad Autonoma de Ciudad Juarez, Juarez, Mexico
Published: January 2022

In this manuscript, we propose an integrated framework based on COmplex PRoportional ASsessment and Step-wise Weight Assessment Ratio Analysis approach within the complex intuitionistic fuzzy soft (CIFS) context. This context is an ideal technique with complex fuzzy foundation that means to denote multi-dimensional data in a concise. In this framework, criteria weights are evaluated by the SWARA technique, and the ranking of alternatives is determined by the COPRAS method using CIFSs. Further, to illustrate the applicability of the presented technique, an empirical case study of ERP software selection problem is taken. A comparative study and sensitivity analysis is presented to verify the strength of the presented methodology.
UHML stability of a class of $ \Delta $-Hilfer FDEs via CRM
Authors: Aderyani Safoura Rezaei ,   School of Mathematics, Iran University of Science and Technology, Narmak, Tehran, Iran, Saadati Reza , O'Regan Donal , Abdeljawad Thabet ,   School of Mathematical and Statistical Sciences, National University of Ireland, Galway, University Road, Galway, Ireland,   Department of Mathematics and Sciences, Prince Sultan University, P. O. Box 66833, 11586 Riyadh, Saudi Arabia,   Department of Medical Research, China Medical University, Taichung 40402, Taiwan
Published: January 2022

We apply CRM based on an alternative FPT to investigate the approximation of a $ \Delta $-Hilfer FDE. In comparison to the Picard method, we show that the CRM has a better error estimate and economic solution.
Development and characterization of ethanol-free spearmint essential oil nanoemulsion for food applications using the low energy technique
Authors: Edris A.E.
Published: January 2022

Different emulsifiable concentrates containing spearmint essential oil (SEO) were made and evaluated for their potential for giving ethanol-free nanoemulsion spontaneously upon dilution into water. Each one of these formulas had its specific composition regarding the type of excipients, surfactants, surfactant/SEO ratio and surfactant concentration. The results of this evaluation indicated that the chemical composition of SEO has a profound effect on the formation and physical stability of the nanoemulsion. The incorporation of excipients such as long chain triglyceride and propylene glycol into the emulsifiable concentrates at only 1.0% can lead to a stable nanoemulsion that resists Ostwald ripening. A particle size measurement showed that the diameter of SEO in the nanoemulsion was 28.2 nm and its nanostructure was maintained for 3 months. The application of a mixture of binary nonionic food-permitted surfactants enhanced the thermal stability of the nanoemulsion at up to 50 ᵒC. The developed ethanol-free SEO nanoemulsion has promising industrial applications in food and beverage flavoring.
Effects of an integrated harvest system on the quality of olive fruit for small producers
Authors: Plasquy E. , Blanco-Roldán G. , Florido M.C. , García J.M.
Published: January 2022

Small producers confront specific challenges when they opt to produce high-quality olive fruit. Limited resources for investing in harvest machinery and manpower are the main reasons for continuing a traditional harvest method that puts the final product and its economic value at risk. This paper discusses the efficiency of an integrated harvest system as a possible solution to these specific challenges. The system is formed by a newly designed manual harvesting device and the use of a cooling room near the olive grove. Both systems were evaluated to assess their feasibility for optimum conditions before processing. The combined effect of the harvesting method and cold storage on the fruit characteristics (incidence of decay, skin color, weight loss, firmness, respiration, and ethylene production) was evaluated on three different varieties (‘Arbequina’, ‘Picual’ and ‘Verdial’) and four different storage times (0, 4, 8, and 14 days). The results indicate that the proposed harvesting method in combination with an appropriate cooling system offers an affordable alternative for obtaining fruit with the best physiological characteristics.
Recovery of Energy and Materials From Small-Scale Tofu Processing Industries in Indonesia
Authors: Sintawardani Neni , Hamidah Umi , Widyarani  , Wulan Diana Rahayuning , Nilawati Dewi
Published: January 2022

Tofu factories are spread across Indonesia as tofu is a cheap source of protein and favorite food for almost all population groups. Most tofu producers are micro/small business owners. In addition to soybeans, clean water is the most important input to produce tofu curd. It will generate a large amount of wastewater and solid waste, which still contains significant amounts of easily biodegradable organic matter. There are often complaints and protests from the public about the pollution in air and water in the area from the discharged waste. Tofu producers know about this, but their limited income and capital force them to ignore the environmental issues. The potential of tofu waste treatment technologies to produce new products or clean materials that can be fed back into the production process is discussed and reviewed to ensure all input materials in the tofu process can be used optimally and efficiently in a closed-loop production process. And it could be implemented easily and economically by the factories.
Engaging Diverse Stakeholders in Interdisciplinary Co-Design Project for Better Service Design
Authors: Nusir Muneer , Tariq Usman , Ahanger Tariq Ahamed
Published: January 2022

The rapid development of information technology (IT) has enabled digital services to evolve continually and support a growing number of internet-enabled devices, along with user diversity. The end-user anticipation within the smart environments, which are internet-enabled, delivery networks and innovative technologies. What tools/methods can support the collaborative design and effectively choreograph the design process with dynamic knowledge between service designers and service users? The cooperative design is recognizable in the design environment with a collection wide-ranged by co-design methods and tools. In-depth interviews uncover contextually appropriate design process requirements from diverse stakeholder groups. A collection of design tools and methods are selected and implemented within a Web-based co-design platform. Uncovered design requirements are subsequently applied in extending the Double Diamond framework prior to operationalization into a design process blueprint with supporting service design tool selection as the main contributions for this paper.
Hepatitis B and Hepatitis C Virus Infection Promote Liver Fibrogenesis through a TGF-β1–Induced OCT4/Nanog Pathway
Authors: Li Wenting , Duan Xiaoqiong , Zhu Chuanlong , Liu Xiao , Jeyarajan Andre J , Xu Min , Tu Zeng , Sheng Qiuju , Chen Dong , Zhu Chuanwu , Shao Tuo , Cheng Zhimeng , Salloum Shadi , Schaefer Esperance A , Kruger Annie J , Holmes Jacinta A , Chung Raymond T , Lin Wenyu
Published: January 2022

Hepatitis B virus (HBV)/hepatitis C virus (HCV) coinfection accelerates liver fibrosis progression compared with HBV or HCV monoinfection. Octamer binding transcription factor 4 (OCT4) and Nanog are direct targets of the profibrogenic TGF-β1 signaling cascade. We leveraged a coculture model to monitor the effects of HBV and HCV coinfection on fibrogenesis in both sodium taurocholate cotransporting polypeptide–transfected Huh7.5.1 hepatoma cells and LX2 hepatic stellate cells (HSCs). We used CRISPR-Cas9 to knock out OCT4 and Nanog to evaluate their effects on HBV-, HCV-, or TGF-β1–induced liver fibrogenesis. HBV/HCV coinfection and HBx, HBV preS2, HCV Core, and HCV NS2/3 overexpression increased TGF-β1 mRNA levels in sodium taurocholate cotransporting polypeptide–Huh7.5.1 cells compared with controls. HBV/HCV coinfection further enhanced profibrogenic gene expression relative to HBV or HCV monoinfection. Coculture of HBV and HCV monoinfected or HBV/HCV coinfected hepatocytes with LX2 cells significantly increased profibrotic gene expression and LX2 cell invasion and migration. OCT4 and Nanog guide RNA independently suppressed HBV-, HCV-, HBV/HCV-, and TGF-β1–induced α-SMA, TIMP-1, and Col1A1 expression and reduced Huh7.5.1, LX2, primary hepatocyte, and primary human HSC migratory capacity. OCT4/Nanog protein expression also correlated positively with fibrosis stage in liver biopsies from patients with chronic HBV or HCV infection. In conclusion, HBV and HCV independently and cooperatively promote liver fibrogenesis through a TGF-β1–induced OCT4/Nanog-dependent pathway.
Long Noncoding RNA HOTAIRM1 Promotes Immunosuppression in Sepsis by Inducing T Cell Exhaustion
Authors: Chen Wankun , Liu Jinlong , Ge Feng , Chen Zhaoyuan , Qu Mengdi , Nan Ke , Gu Jiahui , Jiang Yi , Gao Shenjia , Liao Yun , Wang Chengji , Zhang Hao , Miao Changhong
Published: January 2022

Sepsis is an acute life-threatening disorder associated with multiorgan dysfunction that remains the leading cause of death in intensive care units. As sepsis progresses, it causes prolonged immunosuppression, which results in sustained mortality, morbidity, and susceptibility to secondary infections. Using a mouse model of sepsis, we found that the long noncoding RNA HOTAIRM1 (HOXA transcript antisense RNA myeloid-specific 1) was highly expressed in mice during the late phase of sepsis. The upregulation of HOTAIRM1 was induced by Notch/Hes1 activation and, moreover, was critical for the formation of an immunosuppressive microenvironment. HOTAIRM1 induced T cell exhaustion by increasing the percentage of PD-1+ T cells and regulatory T cells, accompanied by elevated PD-L1. Blockade of either Notch/Hes1 signaling or HOTAIRM1 inhibited T cell exhaustion in late sepsis, having alleviated lung injury and improved survival of mice. Further mechanistic studies identified HOXA1 as a key transcription factor targeted by HOTAIRM1 to regulate PD-L1 expression in lung alveolar epithelial cells. These results implicated that the Notch/Hes1/HOTAIRM1/HOXA1/PD-L1 axis was critical for sepsis-induced immunosuppression and could be a potential target for sepsis therapies.
MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9
Authors: Li Qingwen , Zhang Jiao , Liu Shougang , Zhang Fangfei , Zhuang Jiayi , Chen Yongfeng
Published: January 2022

Psoriasis is a chronic inflammatory skin disease. Although miRNAs are reported to be associated with the pathogenesis of psoriasis, the contribution of individual microRNAs toward psoriasis remains unclear. The miR-17-92 cluster regulates cell growth and immune functions that are associated with psoriasis. miR-17-3p is a member of miR-17-92 cluster; however, its role in dermatological diseases remains unclear. Our study aims at investigating the effects of miR-17-3p and its potential target gene on keratinocytes proliferation and secretion of pro-inflammatory cytokine and their involvement in psoriasis. Initially, we found that miR-17-3p was upregulated in psoriatic skin lesions, and bioinformatic analyses suggested that CTR9 is likely to be a target gene of miR-17-3p. Quantitative reverse-transcriptase PCR and immunohistochemical analysis revealed that CTR9 expression was downregulated in psoriatic lesions. Using dual-luciferase reporter assays, we identified CTR9 as a direct target of miR-17-3p. Further functional experiments demonstrated that miR-17-3p promoted the proliferation and pro-inflammatory cytokine secretion of keratinocytes, whereas CTR9 exerted the opposite effects. Gain-of-function studies confirmed that CTR9 suppression partially accounted for the effects of miR-17-3p in keratinocytes. Furthermore, Western blot revealed that miR-17-3p activates the downstream STAT3 signaling pathway while CTR9 inactivates the STAT3 signaling pathway. Together, these findings indicate that miR-17-3p regulates keratinocyte proliferation and pro-inflammatory cytokine secretion partially by targeting the CTR9, which inactivates the downstream STAT3 protein, implying that miR-17-3p might be a novel therapeutic target for psoriasis.