bluuebunny/crossref_metadata_2025 huggingface dataset:
Out of the Blue Acute May-Thurner Syndrome
Authors: Agarwal Siddharth
Published: January 2021

May-Thurner syndrome (MTS) is defined as extrinsic ilio-femoral venous compression by the aorto-iliac arterial system against vertebral bodies and has been associated with many abnormalities involving the arterial system as well as bony structures around the ilio-caval region. We present an unusual case of a patient who came with phlegmasia cerulea dolens in the setting of acute onset MTS after chiropractic vertebral manipulation and was treated with a multimodal interventional approach, combining pharmaco-mechanical catheter directed thrombectomy along with venoplasty with stenting and subsequent post-procedure anticoagulation and antiplatelet prophylaxis.
Cerebral abscess caused by Streptococcus agalactiae, an unusual presentation
Authors: Fuentes Angelica
Published: January 2021

During the first three months of life, Group B streptococcus or Agalactiae (GBS) can cause meningitis and be associated with cerebrovascular accidents resulting from sepsis and infection of the central nervous system. This article presents the unusual case of a female infant who was afflicted with GBS, meningitis, sepsis complicated by septic shock, ischemic lesions secondary to inflammatory vasculitis and a cerebral abscess accompanied by epileptic seizures with a hypsarrythmia electroencephalographic pattern. A long-term NICU stay with antibiotic management, inotropic support and antiepileptic treatment succeeded in resolving the acute stage of the illness. Out-patient follow-up revealed increased muscle-tone, but delayed neurological development. While this improved significantly with integral rehabilitative therapy, a slight delay still remained. Neuroimaging follow-up at 18 months found malacia-area and core retractions in the left caudate nucleus.
Persepsi Dan Pengambilan Keputusan Milenial Terhadap Instumen Investasi Masa Depan : Studi Literatur
Authors: Rahadi Dedi Rianto , Stevanus Yosua
Published: January 2021

Penelitian ini bertujuan untuk mengetahui persepsi dan pengambilan keputusan yang diambil oleh kaum milenial dalam memilih instrument-intrumen yang digunakan dalam investasi  untuk merencnakan keuangan di masa mendatang dan memberikan pemahaman serta penjelasan mengenai Instumen atau bentuk-bentuk dari investasi  Saat ini yang lebih praktis untuk digunakan. teknologi dan pemikiran manusia semakin maju seiring dengan perkembangan zaman yang cepat dan dinamis banyak instumen investasi baru yang bermunculan yang lebih modern dan mengadopsi media digital pada penelitian ini menggunakan metode studi literatur Kualitatif dengan wawancara. Metode literatur yang berasal dari berbagai sumber seperti : buku, jurnal dan website, dari penelitian mendapatkan hasil bahwa banyak kaum milenial yang berinvestasi dengan media yang memiliki resiko yang rendah seperti : Emas, deposito, properti dan reksadana berikut ini presentase yang didapat dari penelitian menggunakan studi literatur kualitatif hasil dari responden yang diwawancarakan memiliki investasi berupa  deposito sebesar 35 %, property 30%, reksadana 20%, dan saham sebesar 15%.
Pengaruh Perencanaan Sumber Daya Manusia, Rekrutmen dan Penempatan Terhadap Kinerja Karyawan Kantor Perwakilan Bank Indonesia Provinsi Bengkulu
Authors: Saputra Heru , Soleh Ahmad , Gayatri Ida Ayu Made Er Meytha
Published: January 2021

Peningkatan kinerja karyawan dapat dilakukan melalui perencanaan sumber daya manusia, rekrutmen serta penempatan karyawan yang sesuai dengan pendidikan dan keterampilan. Tujuan penelitian ini adalah untuk menganalisis pengaruh perencanaan sumber daya manusia, rekrutmen dan penempatan terhadap kinerja karyawan Kantor Perwakilan Bank Indonesia Provinsi Bengkulu. Metode pengumpulan data dengan membagikan kuesioner kepada 48 karyawan. Analisis data yang digunakan adalah analisis kuantitatif, dengan metode regresi linier berganda, uji determinasi, uji t dan uji F. Hasil penelitian menunjukkan bahwa perencanaan sumber daya manusia, rekrutmen dan penempatan berpengaruh positif dan signifikan secara parsial dan simultan terhadap kinerja karyawan Kantor Perwakilan Bank Indonesia Provinsi Bengkulu.
Penempatan Ulang Material dan Perancangan Sistem Informasi Pengambilan Material Return Berbasis Web di Gudang PT ABC Unit Pembangkit X
Authors: Pratama Ibnu Lukman , Sugito Bambang , Salsabila Laili
Published: January 2021

Salah satu gudang di PT ABC UP X adalah Gudang Material Return. Material return adalah material yang dikembalikan ke gudang karena kelebihan atau sisa pemakaian dalam melaksanakan suatu pekerjaan atau hasil pembongkaran (bekas pakai). Tujuan dari penelitian ini adalah mengoptimalkan barang yang berada di gudang material return melalui aplikasi berbasis web dan mengajukan rancangan desain penempatan material yang lebih efisien. Hasilnya, dalam menentukan prioritas penempatan material, didapati bahwa material mekanik memiliki prioritas tertinggi dibandingkan material instrumentasi (prioritas nomor 2), material listrik (nomor 3) dan material umum. Selain itu berdasarkan dari ukuran material, material berukuran kecil memiliki frekuensi pengeluaran dan penerimaan lebih besar daripada material berukuran besar sehingga material berukuran besar dapat diletakkan jauh dari pintu gudang. Jika material ditata berdasarkan prioritas penempatan material dan ukuran material, maka terjadi prosentase penurunan jarak sebesar 17%. Allowance dalam gudang tersebut minimal 4 meter. Untuk perancangan sistem informasi pegudangan memiliki 4 sistem yaitu admin, user, spv, dan pegawai umum. Setiap sistem memiliki menu yang berbeda. Saran dalam penelitian ini adalah diperlukan prosedur lebih lanjut untuk dilakukan pengecekan material yang jarang terpakai dan pengembangan aplikasi supaya dapat digunakan dalam berbagai aktivitas pergudangan.
The Effect of Competency, Motivation of Work Training on the Work Achievement of Employees Classification Indonesia Bureau of Batam Branch
Authors: Yanti Sri , Haluddin Rusdin , Rumengan Jemmy , Maniah Maniah
Published: January 2021

In this study, the aim of this research is to determine the effect of competence on the work performance of employees of the Batam branch of the Indonesian classification Bureau, to determine the effect of motivation on employee performance of the Batam branch of the Indonesian classification bureau, to determine the effect of training on employee performance at the Batam branch of the Indonesian classification Bureau, to determine the effect of competence , Motivation and training on employee work performance of the Batam branch of the Indonesian classification bureau. The sample of the study amounted to 36 people, this study obtained the results Y = 7.582+ 0.036x1 + 0.414x2 + 0.293x3 + e. With a R2 value of 0.625 (62.5%). The competency variable has a positive and insignificant effect on work performance of 0.036, a significant level of 0.829 is greater than 0.05, the hypothesis Ho is rejected and Ha is accepted, the conclusion of the hypothesis is rejected, motivation has a significant effect on work performance by 0.414, the significant level is 0.001 less than 0.05. , the hypothesis Ha is accepted and Ho is rejected, the conclusion of the hypothesis is accepted. Training has a significant effect on work performance of 0.293 with a significant level of 0.033 smaller than 0.05 hypothesis Ha is accepted and Ho is rejected, the conclusion of the hypothesis is accepted. Competence, motivation and training have an effect on employee work performance. Simultaneous Test (F test) is 17.809 with a significant value of 0.000 where the value is less than 0.05. The hypothesis Ho is rejected and Ha is accepted.
Kepuasan Konsumen Tidak Selalu Linear dengan Loyalitas Konsumen: Analisis pada Restaurant Cepat Saji di Indonesia
Authors: Djayapranata Grace Felicia
Published: January 2021

Kepuasan dan loyalitas seringkali menjadi perhatian praktisi dan akademisi. Bahkan tidak jarang banyak yang menganggap bahwa konsumen yang puas pasti juga loyal dengan perusahaan sehingga  perusahaan berusaha menargetkan kepuasan konsumen sebagai tujuan perusahaan. Beberapa perusahaan bahkan masih menggunakan jargon “konsumen adalah raja” yang mana pandangan ini menganggap bahwa konsumen berada di tempat tertinggi yang mana keinginan dan kebutuhan konsumen harus selalu dipenuhi agar konsumen merasa puas dan diharapkan dengan adanya kepuasan yang didapatkan, konsumen dapat loyal dengan perusahaan yang ditandai dengan pembelian kembali. Sedangkan loyalitas seringkali merupakan kunci untuk meningkatkan dan mempertahankan pangsa pasar. Dengan adanya pelanggan yang setia, maka keberlangsungan perusahaan di masa yang akan datang dapat terjamin. Memang benar bahwa kepuasan seringkali berpengaruh pada loyalitas. Namun hal ini tidak selalu demikian. Terdapat batasan antara kepuasan dengan loyalitas. Menurut Bennett dan Tiele 2004 kepuasan tidak selalu berdampak pada loyalitas, namun hal ini tergantung dari situasi dan konteksnya. Oleh karena itu, tujuan penelitian ini adalah mengetahui apakah kepuasan konsumen selalu linier dengan loyalitas konsumen. Penelitian ini merupakan penelitian deskriptif dengan menggunakan 172 responden dan dilakukan pada konteks restoran cepat saji di Indonesia. Hasil dari penelitian ini adalah kepuasan konsumen tidak selalu linier dengan loyalitas konsumen.
PRESERVATION AND MODELLING FORM OF KUTAI ORIGINAL HOUSE TO MAINTAIN TRADITIONAL ARCHITECTURE
Authors: Putra Hatta Musthafa Aham , Thamrin Nur Husniah
Published: January 2021

Abstract: The traditional house of Kutai is one of the traditional houses located in the region of Kutai Kartanegara, East Borneo, which is currently almost extinct in population. Various houses have adapted to changes in physical shape due to the impact of technology and the needs of their residents. If this problem is not immediately concerned, there is a tendency to be more difficult to recognize the characteristics and character of the Kutai traditional house. The architectural character of the Kutai traditional house including to the structure and construction system used, building materials, cultural ornaments attached to the outside and inside of the building, and the colors. This research is directed to get the formulation of the architectural character of the Kutai traditional house. It is urgent to conserve the Kutai House‘s identity in the future, by considering to preserve the existence and the uniqueness of these traditional building. Keyword: Kutai Architecture, Kutai House, Kutai Traditional House Abstrak: Rumah adat Kutai merupakan salah satu rumah adat yang berlokasi di wilayah Kutai Kartanegara, Kalimantan Timur, yang saat ini telah hampir punah populasinya. Berbagai rumah telah beradaptasi dengan perubahan bentuk fisik dikarenakan dampak teknologi dan kebutuhan penghuninya. Apabila hal ini tidak segera diperhatikan, ada kecenderungan akan lebih sulit mengenali ciri khas dan karakter rumah adat Kutai tersebut. Karakter arsitektur tersebut berupa ruang-ruang pada bangunan rumah adat Kutai, sistem struktur dan konstruksi yang digunakan, material bangunan, ornamen budaya yang melekat pada luar maupun dalam bangunan, hingga warna-warna. Penelitian ini difokuskan untuk mendapatkan rumusan karakter bentuk dari rumah tradisional Kutai. Hal penting yang menjadi tujuan dari penelitian ini adalah untuk menjaga keberadaan dan keunikan dari bangunan Rumah Tradisional Kutai.Kata Kunci: Arsitektur Kutai, Rumah Kutai, Rumah Tradisional Kutai
KLASIFIKASI KEKUMUHAN DAN KONSEP PENANGANAN PERMUKIMAN KUMUH PERKOTAAN (Studi Kasus : Permukiman Lampu Satu, Merauke)
Authors: Joenso Reivandy Christal , Sari Suzanna Ratih
Published: January 2021

Abstract: Lampu Satu settlement is one of 12 slum areas in Merauke Regency. Based on the verification results, Lampu Satu slum settlement is the largest, which is 43.67 hectares or 39.44% of the total area of Merauke Regency slum areas. The purpose of this study is to determine the classification and concept of treatment slum settlements in the Merauke One Light settlement. The analytical method used is descriptive quantitative analysis of the characteristics of the Merauke Lampu Satu slums and measurement of the survey results based on the Minister of Public Works and Housing No. 2 of 2016 to determine the classification of slums and to analyze the concept of handling. The final results obtained in this study are the classification of Lampu Satu slums at a moderate level of slums. The concept of treatment that can be done is prevention with the socialization of licensing procedures, healthy living behaviors, waste management, fire disasters, as well as socialization of regional spatial plans. While the improvement of the quality of settlements is carried out on infrastructure and facilities that are still not by applicable standards and criteria as well as by conducting a resettlement program in settlements located in coastal zones.Keyword: classification; slums; concept of treatmentAbstrak: Permukiman Lampu Satu merupakan salah satu dari 12 lokasi kawasan permukiman kumuh pada Kabupaten Merauke. Berdasarkan hasil verifikasi, permukiman kumuh Lampu Satu merupakan yang terluas yaitu 43,67 hektare atau 39,44% dari total luas kawasan permukiman kumuh Kabupaten Merauke. Tujuan penelitian ini yaitu untuk menentukan klasifikasi kekumuhan dan merumuskan konsep penanganan permukiman kumuh pada permukiman Lampu Satu Merauke. Metode analisis yang digunakan adalah analisis kuantitatif deskriptif terhadap karakteristik permukiman kumuh Lampu Satu Merauke serta pengukuran terhadap hasil survei berdasarkan Peraturan Menteri Pekerjaan Umum dan Perumahan Rakyat Nomor 2 Tahun 2016 untuk menentukan klasifikasi permukiman kumuh dan untuk menganalisis konsep penanganan. Hasil akhir yang diperoleh dalam penelitian ini yaitu klasifikasi permukiman kumuh Lampu Satu pada tingkat kekumuhan sedang.  Konsep penanganan yang dapat dilakukan adalah pencegahan dengan sosialisasi terhadap prosedur perizinan, perilaku hidup sehat, pengelolaan sampah, bencana kebakaran, serta sosialisasi tentang rencana tata ruang kawasan. Sedangkan peningkatan kualitas permukiman dilakukan pada prasarana dan sarana yang masih belum sesuai standar dan kriteria yang berlaku serta dengan melakukan program permukiman kembali (resettlement) pada permukiman yang berada pada kawasan sempadan pantai.Kata Kunci: klasifikasi; permukiman kumuh; konsep penanganan
RELASI JEJARING AKTOR MASYARAKAT SUKU BUGIS SOPPENG DALAM TRADISI MENDIRIKAN RUMAH (MAPPATETTONG BOLA)
Authors: Hatta Asta Juliarman , Ekomadyo Agus S.
Published: January 2021

Every process and stage in phase of constructing of Indonesia’s vernacular architecture is required the role and contribution of individual or several actors so that procession of house construction can be built due to purposes. According to traditions and beliefs of the Bugis community, there are several actors who have different roles and responsibilities during the process of establishing a Buginese-house. This research aims to explore the influence of the actors’ role who are involved in the process of constructing a traditional Bugis house. Correlation and impact of one actor's involvement with other actors will be reviewed based on the perspective of the Actor Network Theory (ANT) by using descriptive qualitative method.  The results revealed that there are 4 stages in the process of building Buginese-house namely the process of constructing a house frame (Mattibang Bola), the process of marking the center of the house (possi bola), the ritual of reading thanksgiving prayer (barzanji), and the process of establishing a house frame (Mappatettong Bola). Founded, Sanro Bola and Panre Bola, namely traditional leaders who have a mandate in the tradition of building houses, are actors who act as controlling actors and are very influential in maintaining the stability of a network in the process of building Buginese-house. Learning from the tradition of building a Buginese-house, the existence of traditional leaders is important, because it has a tradition-based on knowledge base, and this has become a mandate in regulating other actors in working.
TIPOLOGI RUMAH VERNAKULAR BERDASARKAN SISTEM FISIK DI KAMPUNG BANDAR PEKANBARU, RIAU
Authors: Annisa Laili Dwi , Suprapti Atiek , Pandelaki Edward Edrianto
Published: January 2021

The development of the city of Pekanbaru originally came from a small hamlet on the edge of the Siak river. The development of Senapelan (Kampung Bandar now) is very closely related to the development of the Sri Indrapura Siak Kingdom which brought Malay culture and architecture to Bandar Village. To learn the characteristics of an architectural building one of them can be known by studying the typology of the building. Likewise with the characteristics of houses in a settlement, this can be known by examining the typology of the houses. The purpose of this study was to determine the typology of vernacular houses based on physical elements in Kampung Bandar Pekanbaru. The typology of this house will be discussed descriptively with qualitative methods. In this study, a strategy to determine the typology of vernacular houses uses physical system parameters that will discuss typologies based on the character of the material, typologies based on space constraints and typologies based on the structure of the house. The results of the study are expected to be a foundation for maintaining and preserving vernacular houses with Malay architecture in Pekanbaru. It also can be an input for the government to be able to develop the Bandar village area by continuing to emphasize the character of Malay architecture and advanced steps such as conservation so that it can be a positive impact on the city of Pekanbaru.
How research reproducibility challenges librarians’ skill sets. A French librarian’s perspective
Authors: Granger Sabrina
Published: January 2021

Reproducible research requires to dive into a wide range of subjects (e.g.: statistics, study design, scientific computing) that are quite far from French librarians practices and/or initial training. Librarians do have a technical expertise, but horror stories pinpoint that even seasoned experts seem to lose track. In such context, what could be the added value of librarians?
THE APPLICATION OF TECHNOLOGY IN MUSEUMS
Authors:   Universitas Prasetiya Mulya, Indonesia, Suroto Peni Zulandari , Dewantara Made Handijaya ,   Universitas Prasetiya Mulya, Indonesia, Wiradarmo Aulia Ardista ,   Universitas Prasetiya Mulya, Indonesia
Published: January 2021

Alongside with collections in form of historical objects, as well as objects related to human culture, museums have taken an important role in providing education, especially for tourists who visiting a destination. However, at its conditions who have lack of innovation, has implications for declining number in interest of tourists to come and dig deeper into the collections in museum. This research set an objective to answer how could technology applied in museum. Research has been done through Focus Group Discussion (FGD) and depth observation conducted on January 2020, in Jakarta. Nine informants/participants involved during FGD, including 5 museums (public and private), 2 technology providers, and 1 museum users community. Research indicates that strong cooperation between museums and technology providers has been elaborated, in particular in several museums in Jakarta. Augmented Reality and Virtual Reality are two most applications applied. Meanwhile, museums have established several platforms for security and data collection purposes. Both parties will try to add more platforms through video mapping application, projection mapping, virtual tour, and internet of things (IoT) operations. Process of increasing experience and immersion encounters obstacles, to provide additional experience to visitors, so that all five senses that exist in visitors, can enjoy all museum collection. Technology could embrace interaction and immersion to add more experience value on visitors. Thus, tourism industry would be more attractive with the presences of museums.
DESTINATION MARKETING TO IMPROVE DOMESTIC TOURISTS’ RETURN INTENTION
Authors:   President University, Indonesia, Rahmiati Filda
Published: January 2021

Purpose: This study aims to analyze tourist return intention through destination attribute (attraction, accessibility, and amenities), promotion, and destination image mediated by tourist satisfaction. Research methods: The research method used in this research is a quantitative research. This study used 410 respondents who were domestic tourists who had visited Borobudur Temple using purposive sampling. The Partial Least Square-Structural Equation Model (PLS-SEM) used to test hypotheses. Results and discussions: The results of this study indicate that all hypotheses are accepted, that the attributes of the destination (attraction, accessibility, and amenities), promotion, and destination image significantly influence on tourist return intention mediated by tourist satisfaction. Conclusion: It is necessary to improve the quality of destination attributes at Borobudur Temple, promoting not only international tourists but also domestic tourists. It is also important to provide innovations that are expected to attract domestic tourists to make revisit when there are new things for them to experience
Evaluation of ferric carboxymaltose treatment efficacy in women with postpartum iron deficiency anemia
Authors: TEKİN Mustafa , UZUN Navdar Doğuş , UZUN Fulya
Published: January 2021

Aim: Anemia due to iron deficiency is a commonly seen problem among Turkish women. Especially among the pregnant women and particularyly postpartum period its rate increases. In this study, we aimed to evaluate the efficacy of intravenous ferric carbomaltose administration in anemic women in postpartum period. Materials and Methods: The hemoglobin (Hb) and hematocrit (Htc) values of 64 patients who received intravenous ferric carboxymaltose treatment between January 1, 2020 and July 1, 2020 in Mardin State Hospital, Gynecology and Obstetrics Clinic were retrospectively evaluated. Patients who received intravenous iron carbomaltose treatment for postpartum iron deficiency anemia were compared after treatment. The length of stay in the hospital and whether the patient priorly received an erythrocyte suspension were evaluated.8 Results: The population that was given intravenous (iv) ferric carbomaltose mostly due to anemia post-cesarean and normal delivery (NSD) was included in the study Pregnancy week and hospitalization duration means were significantly higher in the C/S group (p
The cultural attitudes of nurses and the analysis of the interactive relation between the nurse and the patient
Authors: ÖZEN Arife , KAHRAMAN Selma
Published: January 2021

ABSTRACT
This study is carried out to determine the effects of nurses’ cultural approach on the patient care, to reveal the relation between the nurse and the patient, and to determine the factors that affect this relation. This study is a cross-sectional descriptive research. 300 participants of the study were nurses working at a hospital from 8am to 5 pm. Multicultural attitude scale and care oriented nurse-patient interaction scale were used to obtain data that was collected between March and June 2016. To analyse the data, descriptive statistics and independence t-test corelation are used. The attitudes and behaviors of the nurses concerning care oriented nurse-patient interaction are positive (significance is 297.4±56.9, sufficiency is 284.8±60.7, and practicality is 281.3±70.7); however, it is found out that the cultural attitudes of the nurses are not positive. The relation between total sufficiency and practicality points of curing oriented nurse-patient interaction scale and multiculturalism attitude scale are evaluated as positive and medium level (r: 0.248, p<0.05, r:0.302, p<0.05).
Awareness among patients taking oral non-steroidal anti-inflammatory drugs as analgesics: a cross-sectional study
Authors: COŞKUNER İpek , YILMAZ Tarik Eren
Published: January 2021

Aim: Non-steroidal anti-inflammatory drugs (NSAIDs), the most used drugs for pain management, are among the most commonly prescribed drugs both in the world and in Turkey. NSAIDs have a serious side effect profile, and their inappropriate use can result in adverse outcomes, including mortality. This study aimed to determine awareness among patients who presented to a family medicine outpatient clinic who used oral NSAIDs for pain relief.

Material and Method: This was a cross-sectional and descriptive study. The universe of the study consisted of patients aged ≥18 years who presented to the Ankara City Hospital Family Medicine Outpatient Clinic at the end of 2019 for any reason who used at least one type of oral NSAID for pain relief. Data were collected using a questionnaire developed by the researchers. Awareness was measured via a survey concerning knowledge and attitude, and knowledge and attitude scores were calculated for each participant. Significance was determined at a p < 0.05 level.

Results: There were 210 participants. The most used NSAID was diclofenac. The most common reasons for painkiller use were headache and musculoskeletal pain. Participants had poor knowledge of the diseases associated with NSAID use, and the most well-known diseases were stomach ulcer and bleeding and kidney failure. Participants' average knowledge scores were low, and average attitude scores were relatively higher. Women had significantly higher knowledge scores than men. Knowledge and attitude scores were positively associated with education and income status. Painkiller use was positively correlated with age and negatively correlated with attitude scores. Participants with chronic diseases had lower attitude scores than those without chronic diseases. Knowledge and attitude scores were positively correlated.

Conclusion: We conclude that participants lacked knowledge about the general characteristics of and risks associated with NSAIDs, widely used, over-the-counter drugs that are found in almost every home. A more cost-effective, knowledgeable, and rational approach is required for NSAID use.
Outcomes of mTORi-involving minimized immunosuppression protocols in renal transplantation
Authors: DEMİR Mehmet Emin , MERHAMETSİZ Özgür , UYAR Murathan , SEVMİS Murat , AKTAS Sema
Published: January 2021

Amaç
Böbrek alıcılarında sitomegalovirüs (CMV), poliyoma B-K virüs (BKV) ve kalsinörün inhibitörü (KNİ) toksisitesi ve malignite geliştiğinde immünosupresyonu azaltmak gerekir. İmmünosupresyon azaltma protokolleri genellikle standart doz KNİ’nin azaltılması ve bir mTORi eklenmesini içerir. Bu çalışmada standart bir immünsupresyon protokolünden mTORi içeren düşük immünosupresyon protokolüne geçtikten sonra ki greft fonksiyonlarını incelemeyi amaçladık.
Metod
Bu tek-merkezli, retrospektif ve gözlemsel çalışma 2014-2016 yılları arasında yapılmış böbrek nakillerinin sonuçlarını içermektedir. Toplan 322 alıcı incelendi ve bunların 231’i çalışmaya alındı. En az 12 ay mTORi alanlar mTORi kolunda değerlendirildi. CMV ve BKV test sonuçları ve hiç greft biyopsisi olmayan alıcılar çalışma dışı bırakıldı. Geriye kalan alıcılar mTORi içermeyen gurubu oluşturdu. mTORi öncesi ve mTORi sonrası birinci ve üçüncü yıl greft sağkalımları ve fonksiyonları karşılaştırıldı.
Sonuçlar
Toplam 231 alıcı ortalama 5 yıl takip edildi. mTORi kolunda CMV ve BKV pozitifliği daha sıktı (p=0,001). Ayrıca, mTORi kolunda akut rejeksiyon sıklığı daha fazlaydı; p=0,001. Tahmini glomerüler filtrasyon hızı (tGFH) mTORi sonrası birinci ve üçüncü yılda daha azdı (p=0,001). Ancak, mTORi sonrası birinci ve üçüncü yıl greft sağ kalım oranları mTORi kullanmayanlar ile benzerdi (p=0,52 ve p=0,72, sırasıyla).
Sonuç
Böbrek alıcılarında mTORi, genellikle immünsupresyon dozunun azaltılmak zorunda olduğu durumlarda (CMV ve BKV viremisi varlığı, KNİ ilişkili nefrotoksisite gibi) düşük doz KNİ’ler ile birlikte kullanılır. Tüm dezavantajlara rağmen mTORi standart protokollere benzer greft sağkalımı sağlayabilir. Ancak, mTORi kullanımı daha fazla akut rejeksiyon ile ilişkilidir ve tGFH’da azalmayı engelleyemeyebilir.
Awareness of breast cancer patients in Poland about clinical trials as available treatment options
Authors: Bartoszkiewicz Mikołaj , Kufel-Grabowska Joanna , Litwiniuk Maria
Published: January 2021

BACKGROUND: Breast cancer is the most common cancer in women in Poland and worldwide. Due to growing morbidity and mortality, patients are looking for new therapeutic options. Clinical trials give cancer patients a chance to access innovative treatment often not available in the national healthcare system. Patient awareness of clinical trials is an essential element for the development of the clinical trials market. OBJECTIVE: The purpose of this survey was to obtain information from breast cancer patients about their knowledge of clinical trials. METHODS: One hundred people were invited to take part in the study, and were recruited into two groups: 50 patients diagnosed with breast cancer less than 40 years of age, and 50 patients with the same disease over 40 years of age. The survey was completed by female patients online. RESULTS: Most of the subjects correctly understood the assumptions of the clinical trial; most often, both groups of subjects obtained information about medical experiments from the Internet. According to the respondents, the most important motivating factor to participate in the clinical trial was the proposed study drug and their current state of health. Patients would more frequently decide to participate in a clinical trial at the time of cancer progression compared to immediately after diagnosis. Commuting to the research center made recruitment of older patients more difficult (40% of older patients versus 16% of younger patients, p = 0.008). CONCLUSION: Patients with breast cancer are aware of clinical trials and decide to participate in them based on the proposed study drug and their current state of health. Progression of the disease is a factor that increases the willingness to participate in clinical trials.
Post-activation performance enhancement of dynamic stretching and heavy load warm-up strategies in elite tennis players
Authors: Moreno-Pérez Victor , Hernández-Davó Jose Luis , Nakamura Fabio , López-Samanes Álvaro , Jiménez-Reyes Pedro , Fernández-Fernández Jaime , Behm David G.
Published: January 2021

OBJECTIVE: The aim of this study was to compare the potential post-activation performance enhancement (PAPE) effects of two different warm-up strategies, involving dynamic stretching (DS) or heavy load leg press (HL) on several key physical qualities in tennis players. METHODS: Twenty-six elite male tennis players (age: 19.22 ± 4.20 years; body mass: 67.37 ± 8.19 kg; height: 1.77 ± 0.07 m) performed both warm-ups, with 48-hours between protocols (DS and HL), performed in a randomized order. Pre- and post-tests included: countermovement jump, 5-m and 10-m sprint, 5-0-5 agility test, and hip extension and flexion range-of-motion which were performed before and after DS and HL warm-up protocols. RESULTS: The DS warm-up led to substantial improvements in 5-m and 10-m sprint, 5-0-5 agility test, countermovement jump, and also to higher hip flexion range-of-motion. The HL warm-up caused impairments in 5-m and 10-m sprints, but improvements in 5-0-5 agility test, countermovement jump and hip extension range-of-motion. Compared to HL, DS warm-up induced possibly to likely positive effects on 5-m and 10-m linear sprint performance, as well as in hip flexion range-of-motion. Nevertheless, no differences in performance improvements in 5-0-5 agility test, countermovement jump and hip extension range-of-motion were found when comparing DS and HL warm-up protocols. CONCLUSION: DS seems to be more effective than HL when performing a short warm-up protocol in elite tennis players.
The effect of sarcopenia in the clinical outcomes following stand-alone lateral lumbar interbody fusion
Authors: Li Hao , Li Jun , Ma Yaojing , Li Fangcai , Xu Zhengkuan , Chen Qixin
Published: January 2021

BACKGROUND: Sarcopenia has been found to affect the postoperative outcomes of lumbar surgery. The effect of sarcopenia on the clinical outcomes in patients who underwent stand-alone lateral lumbar interbody fusion (LLIF) has not yet been examined. OBJECTIVE: To investigate whether sarcopenia affects the Oswestry Disability Index (ODI) and visual analog scale (VAS) score for back pain following single-level stand-alone LLIF. METHODS: Patients who underwent a single level stand-alone LLIF for lumbar diseases were retrospectively investigated. Sarcopenia was defined according to the diagnostic algorithm recommended by the Asian Working Group for Sarcopenia. Patients were divided into the sarcopenia (SP) and non-sarcopenia (NSP) group. Univariate analysis was used to compare with regards to demographics and clinical outcomes. Multivariate logistic regression was performed to elucidate factors predicting poor clinically improvement. RESULTS: Sixty-nine patients were enrolled, with 16 and 53 patients in the SP and NSP group respectively. In the SP group, patients were much older (P= 0.002), their body mass index was significantly lower (P< 0.001), the percent of women was higher (P= 0.042), and the skeletal muscle mass index (SMI) (P< 0.001) and gait speed were much lower (P= 0.005). The postoperative ODI scores were much higher and the improvement rate was much lower (both P< 0.001) in the SP group, whereas VAS scores for back pain showed no difference between the two groups. SMI and gait speed had a moderate and weak correlation with the final ODI score, respectively. Low SMI and low gait speed were independently associated with poor clinical outcomes at the final follow-up. CONCLUSIONS: Sarcopenia impacts the final clinical outcomes of stand-alone LLIF for lumbar diseases. Low SMI and low gait speed were negative impact factors for the clinical improvement after stand-alone LLIF.
Accuracy of the Örebro Musculoskeletal Pain Questionnaire and Work Assessment Triage Tool for selecting interventions in workers with spinal conditions
Authors: Gergelé Eloi , Parent Eric , Gross Douglas P.
Published: January 2021

BACKGROUND: Accurate clinical decision support tools may help clinicians select appropriate interventions for patients with spinal conditions. The Örebro Musculoskeletal Pain Questionnaire (ÖMPQ) is a screening questionnaire extensively studied as a predictive tool. The Work Assessment Triage Tool (WATT) is a clinical decision support tool developed to help select interventions for injured workers. OBJECTIVE: To compare the classification accuracy of the ÖMPQ and WATT to clinician recommendations for selecting interventions leading to a successful return to work in patients with spinal conditions. METHODS: A secondary analysis was undertaken of data from injured workers with spinal conditions assessed between 2013 and 2016. We considered it a success if the workers did not receive wage replacement benefits 30 days after assessment. Analysis included positive likelihood ratio (LR+) as an indicator of predictive accuracy. RESULTS: Within the database, 2,872 patients had complete data on the ÖMPQ, WATT, and clinician recommendations. At 30 days, the ÖMPQ was most accurate for identifying treatments that lead to successful outcomes with a LR+= 1.51 (95% Confidence Interval 1.26–1.82) compared to 1.05 (95% Confidence Interval 1.02–1.09) for clinicians, and 0.85 (95% Confidence Interval 0.79–0.91) for the WATT. CONCLUSIONS: All tool recommendations had poor accuracy, however the ÖMPQ demonstrated significantly better results.
An mRNA characterization model predicting survival in patients with invasive breast cancer based on The Cancer Genome Atlas database
Authors: Li Huayao , Gao Chundi , Zhuang Jing , Liu Lijuan , Yang Jing , Liu Cun , Zhou Chao , Feng Fubin , Liu Ruijuan , Sun Changgang
Published: January 2021

BACKGROUND: Invasive breast cancer is a highly heterogeneous tumor, although there have been many prediction methods for invasive breast cancer risk prediction, the prediction effect is not satisfactory. There is an urgent need to develop a more accurate method to predict the prognosis of patients with invasive breast cancer. OBJECTIVE: To identify potential mRNAs and construct risk prediction models for invasive breast cancer based on bioinformatics METHODS: In this study, we investigated the differences in mRNA expression profiles between invasive breast cancer and normal breast samples, and constructed a risk model for the prediction of prognosis of invasive breast cancer with univariate and multivariate Cox analyses. RESULTS: We constructed a risk model comprising 8 mRNAs (PAX7, ZIC2, APOA5, TP53AIP1,MYBPH, USP41, DACT2, and POU3F2) for the prediction of invasive breast cancer prognosis. We used the 8-mRNA risk prediction model to divide 1076 samples into high-risk groups and low-risk groups, the Kaplan-Meier curve showed that the high-risk group was closely related to the poor prognosis of overall survival in patients with invasive breast cancer. The receiver operating characteristic curve revealed an area under the curve of 0.773 for the 8 mRNA model at 3-year overall survival, indicating that this model showed good specificity and sensitivity for prediction of prognosis of invasive breast cancer. CONCLUSIONS: The study provides an effective bioinformatic analysis for the better understanding of the molecular pathogenesis and prognosis risk assessment of invasive breast cancer.
Analysis of the information management system in the manufacturing process of cigarette enterprises using fuzzy AHP
Authors: Gang Song , Xiaoming Wang , Junfeng Wu , Shufang Li , Zhuowen Liu , Wang Xiaodong
Published: January 2021

In view of the production quality management of filter rods in the manufacturing and execution process of cigarette enterprises, this paper analyzes the necessity of implementing the manufacturing execution system (MES) in the production process of filter rods. In this paper, the filter rod quality system of cigarette enterprise based on MES is fully studied, and the constructive information management system demand analysis, cigarette quality control process, system function module design, implementation and test effect are given. This paper utilizes the Fuzzy analytic hierarchy process to find the optimal system for processing the manufacturing of cigarette. The implementation of MSE based filter rod quality information management system for a cigarette enterprise ensures the quality control in the cigarette production process. Through visualization, real-time and dynamic way, the information management of cigarette production is completed, which greatly improves the quality of cigarette enterprise manufacturing process.
Fuzzy trust based collaborative filtering analysis for mobile user preferences
Authors: Tan Chengfang , Cui Lin , Wu Xiaoyin
Published: January 2021

With the rapid development of mobile terminal devices, mobile user activities can be carried out anytime and anywhere through various mobile terminals. The current research on mobile communication network is mainly focused on extracting useful and interesting information for mobile user from massive and disordered information. However, the sparsity of scoring data matrix results in low quality of recommendation algorithm. In order to overcome this drawback, the traditional collaborative filtering algorithm is improved. First, the user-interest matrix and item-feature matrix were obtained by analyzing mobile user behavior and item attributes. Fuzzy trust based model is utilized for collaborative filtering analysis for mobile user preferences. Then, the similarity between different mobile users was calculated by weighted calculation. With this method, mobile user preference can be predicted effectively, making it possible to recommend rational resource and waste less time in extracting resources out of the massive information. Experimental results show that the proposed algorithm reduces the mean absolute error (MAE) and the impact of sparse scoring matrix data compared with the traditional collaborative filtering algorithm, and improves the recommendation effect to a certain extent.
Research and implementation of the customer-oriented modern hotel management system using fuzzy analytic hiererchical process (FAHP)
Authors: Wang Qian , Zhang Bo
Published: January 2021

Hotel industry, as the pillar industry of the tertiary industry, is developing at a rapid pace under the background of rapid economic growth and strong support for the tourism industry. At the same time, it also faces fierce competition at home and abroad. In the information age, more and more hotels choose informationalized management, in order to reflect the competitive advantage of the enterprise with better services, higher efficiency and lower costs. The current hotel management system has been widely used in all aspects of hotel management, integrating reception, backstage financial processing and material procurement functions in one, which basically meets the needs of the daily management of the hotel. With the advancement of the hotel information process, hotel business data also shows explosive growth. However, these data have not been effectively developed and used. This research proposes Fuzzy based Analytic Hierarchical Process (FAHP), which is utilized for considering user perception to access the making of decision. The business data processing of the management of hotels is limited to simple collection, storage, and statistics. The information obtained is superficial and regular, which cannot meet the current “customer-centered” marketing strategy of the hotel. This topic is based on the conventional hotel management system, using data mining technology to extract useful information from the existing hotel business data to establish customer segmentation model and support the decision layer to analyze the data from multi-angle and multi-level around the decision-making topic, so as to truly realize the “customer-centered” concept, improve hotel service level and improve the core competitiveness of enterprises.
Linguistic interval-valued q-rung orthopair fuzzy TOPSIS method for decision making problem with incomplete weight
Authors: Khan Muhammad Sajjad Ali , Khan Amir Sultan , Khan Israr Ali , Mashwani Wali Khan , Hussain Fawad
Published: January 2021

The aim of this paper is to introduce the notion of linguistic interval-valued q-rung orthopair fuzzy set (LIVq-ROFS) as a generalization of linguistic q-rung orthopair fuzzy set. We develop some basic operations, score and accuracy functions to compare the LIVq-ROF values (LIVq-ROFVs). Based on the proposed operations a series of aggregation techniques to aggregate the LIVq-ROFVs and some of their desirable properties are discussed in detail. Moreover, a TOPSIS method is developed to solve a multi-criteria decision making (MCDM) problem under LIVq-ROFS setting. Furthermore, a MCDM approach is proposed based on the developed operators and TOPSIS method, then a practical decision making example is given in order to explain the proposed method. To illustrate to effectiveness and application of the proposed method a comparative study is also conducted.
A restaurant recommendation approach with the contextual information
Authors: Chen Lei , Xia Meimei
Published: January 2021

Recommender systems can recommend products by analyzing the interests and habits of users. To make more efficient recommendation, the contextual information should be collected in recommendation algorithms. In the restaurant recommendation, the location and the current time of customers should also be considered to facilitate restaurants to find potential customers and give accurate and timely recommendations. However, the existing recommendation approaches often lack the consideration of the influence of time and location. Besides, the data sparsity is an inherent problem in the collaborative filtering algorithm. To address these problems, this paper proposes a recommendation approach which combines the contextual information including time, price and location. Instead of constructing the user-restaurant scoring matrix, the proposed approach clusters price tags and generates the user-price scoring matrix to alleviate the sparsity of data. The experiment on Foursquare dataset shows that the proposed approach has a better performance than traditional ones.
OWA aggregation with dual preferences for basic uncertain information
Authors: Jin LeSheng , Yager Ronald R. , Špirková Jana , Mesiar Radko , Paternain Daniel , Bustince Humberto
Published: January 2021

Basic Uncertain Information (BUI) as a newly introduced concept generalized a wide range of uncertain information. The well-known Ordered Weighted Averaging (OWA) operators can flexibly and effectively model bipolar preferences of decision makers over given real valued input vector. However, there are no extant methods for OWA operators to be carried out over given BUI vectors. Against this background, this study firstly discusses the interval transformation for BUI and elaborately explains the reasonability within it. Then, we propose the corresponding preference aggregations for BUI in two different decisional scenarios, the aggregation for BUI vector without original information influencing and the aggregation for BUI vector with original information influencing after interval transformation. For each decisional scenario, we also discuss two different orderings of preference aggregation, namely, interval-vector and vector-interval orderings, respectively. Hence, we will propose four different aggregation procedures of preference aggregation for BUI vector. Some illustrative examples are provided immediately after the corresponding aggregation procedures.
Big data reliability: A critical review
Authors: Sharma Shalini , Kumar Naresh , Kaswan Kuldeep Singh
Published: January 2021

Big data requires new technologies and tools to process, analyze and interpret the vast amount of high-speed heterogeneous information. A simple mistake in processing software, error in data, and malfunctioning in hardware results in inaccurate analysis, compromised results, and inadequate performance. Thus, measures concerning reliability play an important role in determining the quality of Big data. Literature related to Big data software reliability was critically examined in this paper to investigate: the type of mathematical model developed, the influence of external factors, the type of data sets used, and methods employed to evaluate model parameters while determining the system reliability or component reliability of the software. Since the environmental conditions and input variables differ for each model due to varied platforms it is difficult to analyze which method gives the better prediction using the same set of data. Thus, paper summarizes some of the Big data techniques and common reliability models and compared them based on interdependencies, estimation function, parameter evaluation method, mean value function, etc. Visualization is also included in the study to represent the Big data reliability distribution, classification, analysis, and technical comparison. This study helps in choosing and developing an appropriate model for the reliability prediction of Big data software.