bluuebunny/crossref_metadata_2025 huggingface dataset:
Türkiye’nin Kıyı Şehirlerinde Yürütülen Akıllı Şehir Projelerinin Kıyılarda Dirençlilik Oluşturma Rolünün Değerlendirilmesi
Authors: Kılıç Mehtap
Published: March 2024

Türkiye kıyı bölgelerinin varlığı ile stratejik öneme sahip bir ülke konumundadır. Kıyı bölgelerinde ticari faaliyetlerin, işletmelerin ve turizm faaliyetlerinin aktif olması başta ekonomik yönde olmak üzere birçok avantaj sağlamaktadır. Fakat son dönemlerde iklim değişikliği başta olmak üzere çeşitli nedenlerle afetlerin etkisini arttırması sonucu kıyı bölgeleri birçok sorunla karşı karşıya kalmıştır. Deniz seviyesinin yükselmesi, kıyı erozyonları ve su baskınlarının artması gibi sebeplerle kıyı şehirlerinin dirençliliğini giderek azalmıştır. Dirençliliğin arttırılması amacıyla günümüzde teknolojik gelişmeler ön plana çıkmaktadır. Bu gelişmelerden bazıları; erken uyarı sistemleri kullanılarak olası zararları azaltmak, uzaktan algılama ve coğrafi bilgi sistemlerinin kullanılması ile risk analizleri ve risk haritaları oluşturmak, haberleşme altyapısının güçlendirilmesi ile uyarı sürecini hızlandırmak ve hava tahmin sistemleri ile meteorolojik uyarlar yapmaktır. Bahsi geçen uygulamaların çokça kullanıldığı akıllı şehirlerde özellikle afetlere karşı dirençlilik oluşturmak temel amaçtır. Türkiye’ de de bu doğrultuda çeşitli akıllı şehir projeleri yürütülmektedir. Çalışmanın kapsamı gereği kıyı şehirlerinde yürütülen akıllı şehir projelerinin afet ve acil durumlara yönelik dirençlilik oluşturup oluşturmadığı, Çevre, Şehircilik ve İklim Değişikliği Bakanlığının koordinasyonunda yürütülen projelerin içerik analizi yöntemi ile incelenmesi sonucunda ortaya çıkarılmıştır. Neticede Türkiye’nin kıyı tehlikelerini ele alan projeler üretmekten çok, kıyı bölgelerindeki tehlikeleri ele alan projeler ürettiği sonucuna ulaşılmıştır. Sel, heyelan ve aşırı hava olayları gibi afetlere yönelik erken uyarı sistemlerinin geliştirilmesi, CBS alt yapısı oluşturulması gibi uygulamalar ülkemizde en çok alınan önlemler arasındadır. Bu önlemler kıyı tehlikelerinin de önlenmesinde kullanılıyor olsa da özel olarak bu amaca hizmet eden sensör ağları, uzaktan algılama ve veri analitiği gibi teknolojiler yaygınlaştırılmalı ve kıyılarda akıllı kentsel planlama çözümleri geliştirilmelidir.
30 Ekim 2020 İzmir ve 6 Şubat 2023 Kahramanmaraş Depremlerinin Teknik ve Yönetsel Karşılaştırılması
Authors: Özmen Bülent , Varol Nehir
Published: March 2024

Türkiye’nin sismik riskinin yüksek olması depremlere sık maruz kalmasına neden olmaktadır. Maalesef büyüklüğü 6.5 Mw ve üzerindeki depremler, risk azaltma çalışmalarının yetersizliği nedeniyle can ve mal kaybına yol açmaktadır. Bu çalışmada, 30 Ekim 2020 İzmir ve 6 Şubat 2023 Kahramanmaraş depremleri teknik ve yönetimsel açıdan değerlendirilmiştir. İzmir depreminde 117 vatandaşımız hayatını kaybetmiş, 1034 vatandaşımız yaralanmış, ağır hasarlı ve yıkılan bina sayısı 124 olmuştur. Kahramanmaraş depremlerinde ise 53.597 vatandaşımız hayatını kaybetmiş, 107.213 vatandaşımız yaralanmış ve yıkılan bina sayısı ise 39.000 olmuştur. Teknik açıdan bakıldığında iki depremde de bina yıkımlarının daha çok zemin-bina ilişkisinden kaynaklandığı görülmektedir.

AFAD (Afet ve Acil Durum Yönetimi Başkanlığı) koordinasyonunda, 2022 yılında 81 ilin İl Risk Azaltma Planları (İRAP) tamamlanmış ve Türkiye Afet Risk Azaltma Planı (TARAP) yürürlüğe girmiştir. Bundan sonraki süreçte belirlenen öncelikli eylemler doğrultusunda risk odaklı çalışmaların daha ağırlıklı olarak devam edeceği düşünülmektedir. Deprem sonrası müdahale ve iyileştirme süreçlerinde daha başarılı olarak görülen Türkiye, risk odaklı çalışmalara ve deprem özelinde zemin-bina uyumu gözetilerek yapılaşmaya öncelik vermek durumundadır.
FAKTOR-FAKTOR YANG MEMPENGARUHI PENGETAHUAN MASYARAKAT DI KOTA KUPANG MENGENAI COVID-19
Authors: So’o Rosina Wiwin , Ratu Kristian , Folamauk Conrad Liab Hendricson , Amat Anita Lidesna Shinta
Published: March 2024

Coronavirus Disease (COVID-19) merupakan penyakit yang dapat menular sehingga jumlah kasus terus mengalami peningkatan. Pengobatan yang spesifik untuk COVID-19 belum ditemukan. Oleh karena itu diperlukan berbagai upaya pencegahan. Pengetahuan mengenai COVID-19 diperlukan selama masa pandemi karena berpengaruh pada sikap pencegahan COVID-19. Pengetahuan itu sendiri dipengaruhi oleh berbagai faktor internal maupun eksternal. Tujuan penelitian untuk mengetahui hubungan umur, pendidikan terakhir, dan pekerjaan dengan pengetahuan mengenai COVID-19 pada masyarakat di Kota Kupang. Metode penelitian analitik observasional dengan rancangan cross sectional yang dilakukan pada masyarakat di Kota Kupang yang berusia 17-55 tahun, memiliki akses internet dan mampu menggunakan google form, berdomisili di Kota Kupang. Penelitian dilakukan dengan mengisi kuesioner pengetahuan mengenai COVID-19 yang berisi 15 pertanyaan. Teknik pengambilan sampel yaitu kombinasi  conveninence sampling dan snowball sampling dan total sampel yang memenuhi kriteria inklusi dan eksklusi adalah 275 orang. Penelitian ini dianalisis secara univariat dan bivariat menggunakan uji Contingency Coefficient. Hasil penelitian dari 275 responden, terdapat 138 orang (50,2%), dengan pengetahuan mengenai COVID-19 dalam kategori baik, cukup 114 orang (41,5%) dan pengetahuan kurang 23 orang (8,4%). Hasil analisis bivariat dengan uji Contingency Coefficient didapatkan tidak ada hubungan umur (p=0,258), pendidikan terakhir (p=0,332), pekerjaan (p=0,194) dengan pengetahuan mengenai COVID-19. Kesimpulan penelitian tidak ada hubungan antara usia, pendidikan terakhir, pekerjaan dengan pengetahuan masyarakat di Kota Kupang mengenai COVID-19.
Mask innovations on the eve of high NA EUV lithography
Authors: Philipsen Vicky , Frommhold Andreas , Thakare Devesh , Libeert Guillaume , Lee Inhwan , Franke Joern-Holger , Bekaert Joost , Van Look Lieve , Pellens Nick , De Bisschop Peter , Jonckheere Rik , Kovalevich Tatiana , Wiaux Vincent , Hendrickx Eric
Published: March 2024

We are on the eve of the next big step in lithography technology with the introduction of high numerical aperture EUV. The change from NA 0.33–0.55 in EUV lithography is an increase of 67%, which is the largest jump in the last decades, and puts tight requirements on focus and edge placement. Moreover, the lithography system has changed from fully isomorphic, i.e. same demagnification in all directions, to an anamorphic system, i.e. the demagnification in scan direction has doubled with respect to the slit direction. At imec we are fostering the ecosystem surrounding the lithography tool. In this paper we focus on the imaging and mask innovations supporting the EUV ecosystem, which are categorized into four areas: novel absorber masks, stitching, mask variability, and innovative imaging solutions. The current drivers of IC manufacturers implementing (high NA) EUV lithography (EUVL) are reduction of the EUV exposure dose and decrease in wafer stochastics. We discuss how these four areas have the potential to deliver in EUVL an increase in productivity, an improvement in the process window and a reduction in stochasticity at wafer level.
Optical fiber-based acoustic intensity microphone for high-intensity airborne ultrasound measurement
Authors: Hoshi Takayuki , O-oka Yoshiki
Published: March 2024

The increasing use of airborne ultrasonic waves in daily life, driven by advances in parametric and phased arrays, has led to innovative applications like highly directional speakers, non-contact tactile feedback, 3D acoustic levitation, and medical therapies. These advancements necessitate accurate measurement of high-intensity ultrasonic waves, exceeding the capability of traditional microphones limited to around 160 dB, and highlight the growing importance of measuring the sound field not merely as scalar (sound pressure) but as vector (acoustic intensity) to accommodate future technological developments. This paper introduces an acoustic intensity microphone using optical fibers as probes to overcome these limitations. The proposed method replaces the two ordinary microphones used in the traditional acoustic intensity measurement method with thin optical fibers, minimizing sound field disturbance. Experimental validation and the structure of a practical acoustic intensity microphone are discussed, building upon foundational work presented at USE2023 with added verification and insights.
Suppression of effects of the synchronization error with adaptive down-conversion for underwater acoustic communication
Authors: Deguchi Mitsuyasu , Kida Yukihiro , Watanabe Yoshitaka , Shimura Takuya
Published: March 2024

In underwater acoustic communication, inaccurate synchronization can cause an incorrect estimation of the uniform Doppler shift and degrade the demodulation performance. In this paper, it is mathematically described how the inaccurate synchronization affects the demodulation procedure. Moreover, it is also shown theoretically that adaptive down-conversion, which has been proposed to suppress the effects of the nonuniform Doppler shift, reduces the degradation of the demodulation performance caused by the inaccurate synchronization. Furthermore, the improvement in the demodulation performance by the adaptive down-conversion is evaluated using experimental data. The demodulation results of the addition of intended synchronization errors clearly show that the adaptive down-conversion reduced the effects of the synchronization errors and improved the demodulation performance in the case of inaccurate synchronization.
Formation of one-dimensionally self-aligned Si-QDs and their local electron discharging properties
Authors: Imai Yuki , Makihara Katsunori , Yamamoto Yuji , Wen Wei-Chen , Schubert Markus Andreas , Baek Jongeun , Tsuji Ryoya , Taoka Noriyuki , Ohta Akio , Miyazaki Seiichi
Published: March 2024

Self-aligned Si-quantum-dots (Si-QDs) with an areal density as high as ∼1011 cm−2 have been fabricated on ultrathin SiO2 by using a ∼4.5 nm thick poly-Si on insulator (SOI) substrate, and controlling low-pressure CVD using monosilane (SiH4), and followed by thermal oxidation. By controlling the thermal oxidation processes of Si-QDs and the poly-Si layer, we have successfully demonstrated the vertical alignment of Si-QDs, where the Si-QDs are also used as a shadow mask of the underlying poly-Si layer. We also demonstrated in-plane alignment of the one-dimensionally self-aligned Si-QDs on line-patterned SiO2. In addition, from surface potential measurements by using atomic force microscopy/Kelvin probe force microscopy, we confirmed that the initial surface potential change caused by valence electron extraction from the dots to the tip was stably maintained until ∼120 min, implying the quantum confinement effect at discrete energy levels of the upper and lower-QDs.
The Future of Fashion Retail: Virtual Experiences and E-Commerce Integration
Authors:   School of Computer Science and Engineering, Anhui University of Science and Technology China., Ahmad Sadaf , Yu Zhang  ,   School of Computer Science and Technology, Anhui University of Science and Technology China., Yamin Iqra ,   School of Computer Science and Engineering, Anhui University of Science and Technology China., Ahmad Wafa ,   School of Economics & Management, Harbin Institute of Technology China.
Published: March 2024

This innovative research integrates methodologies from two distinct studies to advance our comprehension of immersive virtual experiences within the realms of fashion and e-commerce. By amalgamating insights from both methodologies, this refined approach introduces novel components, including a virtual shopping environment, post-VR shopping behavior analysis, biometric data collection, extended interviews, longitudinal study design, and control group implementation. Participants engaged in 360-degree VR fashion shows and virtual shopping experiences using the Oculus Quest 2, while their physiological responses were meticulously monitored. Following the VR encounters, participants navigated a virtual store, and their subsequent shopping behavior was methodically tracked. Extended interviews delved into enduring effects, while a longitudinal study examined the evolution of attitudes over a three-month period. The inclusion of a control group ensured the robustness of causal inferences. This sophisticated methodology promises a comprehensive exploration of the intricate interplay between immersive virtual encounters and consumer behaviors, providing nuanced insights into the evolving landscape of virtual consumption. By embracing cutting-edge elements such as biometric data and virtual shopping environments, this research aims to unravel the multifaceted effects of immersive virtual experiences, contributing to a deeper understanding of consumer interactions with virtual environments and shaping the future trajectory of fashion and e-commerce.
Implementasi Metode Kruskal dan Open Street Map Pada Pencarian Lokasi Anjungan Tunai Mandiri (ATM) Kota Bengkulu
Authors: MKom Kirman, , Feri Kurniawan
Published: March 2024

Salah satu fasilitas umum yang paling sering dicari oleh masyarakat adalah mesin ATM (Anjungan Tunai Mandiri). Mesin ATM adalah suatu alat el-ektronik yang dapat melayani nasabah dalam proses transaksi uang seperti penarikan uang tunai, cek saldo, dan transfer uang ke rekening orang lain. Berdasarkan hal tersebut, maka masyarakat memerlukan suatu aplikasi pen-carian lokasi ATM terdekat. Hal ini tentunya dapat meningkatkan efektivitas penggunaan waktu oleh masyarakat, sehingga masyarakat dapat mengatur waktunya untuk melakukan kegiatan lainnya. Berdasarkan masalah dan tujuan penelitian yang dilakukan maka dapat di-tarik kesimpulan sistem pencarian jarak ATM berdasarkan metode Kruskal dan Open Street Map (OSM) dapat berjalan dengan baik, dan memiliki ting-kat keberhasilan yang didapatkan dari pendapat reseponden sebesar 92% tingkat keberhasilan.
Video Processing Approaches: A Review
Authors: Akewar Mayur
Published: March 2024

Video processing is a fundamental task in computer vision and multimedia
analysis, encompassing various techniques for capturing, analyzing, and
manipulating video data. In this paper, we conduct a comprehensive
review of video processing approaches, covering topics such as video
enhancement and video content detection. We examine the evolution of
video processing techniques, discuss their applications across different
domains, and highlight current challenges and future research
directions.
Adherence to Infection Prevention Practice Standard Protocol and Associated Factors Among Healthcare Workers
Authors: Babore Getachew Ossabo , Eyesu Yaregal , Mengistu Daniel , Foga Sisay , Heliso Asnakech Zekiwos , Ashine Taye Mezgebu
Published: March 2024

Introduction

Healthcare-associated infection affects more than 100 million patients annually. Healthcare workers’ poor adherence to standard infection prevention and control procedures can result in many negative consequences, ranging from disability to death.

Methods

A facility-based, cross-sectional study was conducted in June 2021 among 379 healthcare workers selected using a stratified random sampling technique. All types of healthcare providers except pharmacy professionals were included in the study. Standardization and validation of the study tool were performed ahead of data collection. Multivariable regression was used to assess the variables associated with adherence.

Results

The study found that 60.2% of healthcare workers (95% CI, 55.1–65.2) had good adherence to infection prevention practices, and 68.7% and good knowledge of infection prevention practices. Training on infection prevention methods (adjusted odds ratio [AOR] = 1.68; 95% CI, 1.04–2.72), availability of water supply at hand washing station (AOR = 2.90; 95% CI, 1.62–5.31), and attitude toward infection prevention (AOR = 2.64; 95% CI, 1.65–4.24) were identified as predictors of adherence to infection prevention and control procedures.

Conclusion

More than half of the participants had good adherence to infection prevention guideline practices. In-service infection prevention training, a consistent water supply at the hand washing station, and a positive attitude of participants were associated with good adherence to infection prevention practices.
Effect of Mckenzie Exercise to Increase Craniovertebral Angle in Forward Head Posture of Adolescent
Authors: Laksmi Raras Hestina , Nur Hidayati Nitaya Putri , Ratmawati Yuliana
Published: March 2024

BACKGROUND : adolescents with low physical activity and smartphone addiction has been indicated to reduced the craniovertebral angle, there by causing a forward head posture and increasing scapular dyskinesis, characterized by a craniovertebral angle (CVA) less than 50o. McKenzie is one of exercise that can helm correct posture in forward head posture
AIMS : to determine the effect of the McKenzie exercise on increasing the craniovertebral angle in the forward head posture of adolescents.
METHOD : students of MAN 1 Surakarta (Islamic Boarding School) with advanced head posture, aged 14-17 years using a simple random sampling technique divided into group I as the intervention group (n=16) and group II as the control group (n=14). Group I was given treatment of McKenzie exercise 3 times a week for 4 weeks, and the control group was not given any treatment. The Craniovertebral angle were assessed using photo analysis with Image-J application.
RESULT : The results of the study indicate that the characteristics of respondents according to age are mostly 16 years old. The mean NDI score in the intervention group was 23,63 and the mean NDI score in the control group was 24,60. The results of statistical test using independent samples test showed that there was a significant difference during the intervention and the control group (p=0,000)
CONCLUSION : McKenzie's exercise can affect to increasing the craniovertebral angle in the forward head posture of adolescents.
Effectiveness of Kelly Plication Method on Clinical Improvement in Stress Urinary Incontinence Patients
Authors: Notohatmodjo Puspitasari , Pramono Besari Adi , Mulyantoro Inu , Kristanto Herman , Purnaningtyas Dewi Astri , Mochtar Arufiadi Anityo , Mulyantoro Erwinanto
Published: March 2024

BACKGROUND: Patients with pelvic organ prolapse (POP) usually present with POP, but stress urinary incontinence (SUI) is also found during history taking and physical examination. As a result, the complaint of SUI is persistent despite POP surgery. Therefore, SUI found along with POP and undergoing surgery can be performed Kelly plication method.
OBJECTIVES: To examine the effectiveness of Kelly's plication method on clinical changes and quality of life of patients suffering from SUI.
METHODS: A single cohort prospective one-group pretest-posttest design conducted at RSUP Dr. Kariadi Teaching Hospital Semarang involving 31 research subjects. All subjects were measured preoperative IIQ-7 questionnaire and pad test. Then, all subjects will undergo Kelly method surgery. Postoperative evaluation will be conducted 3 months later, including measurement of the IIQ-7 questionnaire and pad test. All data will be analyzed with univariate and bivariate analysis using paired t-test and Wilcoxon test.
RESULTS:  The effectiveness rate of Kelly's plication method was 58.06% in this study. Most of the subjects were aged 50-59 (38.7%) years and had experienced menopause (87.1%). Correlation analysis of baseline data on the degree of preoperative SUI showed that the degree of POP correlated SUI. The Pad test and IIQ-7 questionnaire test showed a significant decrease in postoperative measurements in the treatment group (p: <0.001 & p: <0.001).
CONCLUSIONS: Kelly's plication method is effective in treating SUI.
Pregnancy Associated Plasma Protein-A (PAPP-A) as a Marker to Distinguish Normotensive with Early 2nd Trimester and Late 3rd Trimester Onset of Preeclampsia
Authors: Simangunsong Ragam Pesona , Kristanto Herman , Iskandar Mirza , Thaufik Syarief , Pramono Besari Adi , Mochtar Arufiadi Anityo
Published: March 2024

Introduction: Preeclampsia is a hypertensive condition that occurs after 20 weeks of gestation accompanied by target organ damage. Complications of preeclampsia can cause intrauterine fetal growth retardation, and placental hypoperfusion, even in the most serious situations, namely termination of pregnancy and death of the fetus and/or mother. Pregnancy-associated plasma protein-A (PAPP-A) is a high molecular weight glycoprotein that is produced in the placenta and secreted into the maternal bloodstream. However, based on several studies that have been conducted, there is uncertainty in the results of assessing PAPP-A levels obtained in pregnant women in the second and third trimesters.
Aim: Proving differences in PAPP-A levels in the second and third trimesters in the incidence of early-onset preeclampsia and normotensive pregnancy.
Methods: An analytic observational study with a cross-sectional approach was carried out in the delivery room of RSUP Dr. Kariadi Semarang, Halmahera Health Center, Ngesrep Health Center, Bulu Health Center, and private midwife practice in Semarang City. The subjects of the study were six 2nd-trimester preeclampsia patients, fourteen 3rd-trimester preeclampsia patients, and twenty normotensive pregnancy patients who met the inclusion and exclusion criteria. Data were analyzed using Mann Whitney with a significance of p<0.05
Results: There was a significant difference in PAPP-A levels (p<0.001) between the preeclampsia and normotensive pregnancy groups, whereas PAPP-A levels were higher in the preeclampsia group. There were significant differences in PAPP-A levels (p<0.001) between the 2nd-trimester preeclampsia, 3rd-trimester preeclampsia, and normotensive pregnancies, where the highest PAPP-A levels were found in the 2nd-trimester preeclampsia group.
Conclusion: There was a significant difference in PAPP-A levels between the second and third trimesters of early-onset preeclampsia compared to normotensive pregnancies, where PAPP-A levels were higher in the second and third trimesters of early-onset preeclampsia. Elevated PAPP-A levels in the second and third trimesters are associated with an increased risk of early-onset preeclampsia.
PROFILE AND CLINICAL OUTCOMES OF DRUG THERAPY FOR SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS IN YOGYAKARTA HEALTH SERVICES
Authors: Adnan Adnan , Nur Afriani Vivi Alna
Published: March 2024

Lupus Eritematosus Sistemik (SLE) adalah kelainan autoimun yang menyebabkan peradangan kronis. Penyebab SLE adalah jaringan sehat yang diserang oleh sistem imun tubuh. Gejala pada SLE bermacam-macam karena didasarkan pada organ yang diserang oleh autoantibodi tubuh. Penelitian ini bertujuan untuk mengetahui profil pengobatan dan hasil klinis pada pasien SLE. Jenis penelitian yang digunakan adalah observasional deskriptif, dengan menggunakan data retrospektif dari rekam medis pasien SLE rawat jalan dan rawat inap di RS Panti Rapih Yogyakarta. Profil data pengobatan dan hasil klinis diterapkan secara deskriptif. Pasien SLE berjumlah 20 orang, 18 perempuan (90%) dan dua laki-laki (10%). Usia 20-59 tahun 19 pasien (95%), ≥ 60 tahun 1 pasien (5%). Penyakit penyertanya adalah gangguan ginjal sebanyak 10 pasien (50%) dan gangguan pernafasan sebanyak 8 pasien (40%). Terapi obat SLE yang diterima adalah kortikosteroid sebanyak 15 orang (75%), imunosupresan sebanyak 12 orang (60%), NSAID sebanyak 10 orang (50%), dan obat antimalaria sebanyak lima orang (25%). Pasien mengalami penurunan skala nyeri sebanyak tujuh orang (35%), gejala remisi dan keluhan 5 (25%), penurunan nyeri dan remisi 4 (20%), dan tidak ada hasil klinis 4 (20%). Berdasarkan usia, yang paling dominan adalah usia dewasa (20-59 tahun), dan perempuan paling banyak menderita SLE; penyakit penyerta terbanyak adalah gangguan ginjal, dan obat yang paling banyak diterima pasien SLE adalah kortikosteroid. Hasil pencapaian klinis adalah pengurangan rasa sakit dan remisi.
KARAKTERISASI SIMPLISIA DAN UJI ANTIBAKTERI BUAH SAWO MUDA (Manilkara zapota L) TERHADAP PERTUMBUHAN BAKTERI STAPHYLOCOCCUS AUREUS
Authors: Khasanah Heti rais , Pudiarifanti Nadia
Published: March 2024

Berbagai macam tumbuhan yang terdapat di Indonesia banyak dimanfaatkan oleh masyarakat untuk menyembuhkan berbagai macam penyakit. Obat tradisional yang sudah digunakan sejak bertahun tahun dinilai lebih aman daripada obat kimia karena efek samping obat trdisional yang relatif lebih sedikit jika digunakan secara tepat. Salah satu tanaman yang telah digunakan buah sawo (Manilkara zapota L) yang digunakan secara alami untuk pengobatan diare dimasyarakat, selain itu juga msyarakat menggunakan untuk mnegtasai penyakit tifus. Penelitian ini dilakukan untuk mengetahui karakterisasi dan uji aktivitas antibakteri buah sawo muda terhadap pertumbuhan bakteri Staphylococus aureus. Metode pembuatan extrak dengan cara maserasi dengan alkohol 70% dan pengujian aktivitas antibakteri dengan menggunakan difusi agar. Pembuatan exstrak dengan cara maserasi dengan alkohol 70% dan pengujian aktivitas antibakteri dengan menggunakan difusi agar. Dari hasil penelitian ini didapatkan  bahwa ada beberapa karakterisasi tidak sesuai persyaratan yang telah ditentukan seperti kadar air, dimana pada penelitian ini kadar air yang diperoleh lebih tinggi dari persyaratan yang telah ditetapkan Hasil pengujian sekrining fitokimia pada buah sawo muda positif  senyawa flavonoid, tanin dan triterpenoid. Pengujian aktivitas antibakteri dengan berbagai konsentrasi diperoleh zona hambat kuat dan sedang. Aktivitas antibakteri yang paling tinggi terdapat pada konsentrasi 80%.
POTENSI KRIM EKSTRAK ETANOL DAUN MENGKUDU (Morinda citrifolia L.) TERHADAP Staphylococcus aureus
Authors: Zaky Mohammad , Junaidin Junaidin , Yulyianti Riandani
Published: March 2024

Daun Mengkudu (Morinda citrifolia L.) merupakan tanaman yang memiliki kandungan senyawa alkaloid, flavonoid, tanin, saponin dan terpenoid yang berfungsi sebagai antibakteri. Ekstrak daun mengkudu telah diketahui memiliki aktivitas antibakteri Staphylococcus aureus namun pengujiannya dalam bentuk sediaan krim belum pernah dilakukan. Tujuan penelitian ini untuk melihat aktivitas antibakteri ekstrak etanol 96% daun mengkudu (Morinda citrifolia L.) terhadap bakteri Staphylococcus aureus dalam bentuk sediaan krim. Metode yang dipakai yaitu metode difusi sumuran. Bahan aktif yang dipakai adalah ekstrak etanol 96% daun mengkudu dengan variasi F0, F1 25%, F2 50% dan F3 75%. Hasil penelitian membuktikan bahwa daun mengkudu dapat diformulasikan dalam bentuk sediaan krim dengan sifat mutu yang baik. Hasil pengujian organoleptik krim berbentuk semisolid berwarna hijau dengan bau khas daun mengkudu,rasa pahit dan homogen. Krim mempunyai pH 6,1 – 6,6 yang aman bagi kulit, daya sebar memenuhi syarat (5-7 cm), ,viskositas memenuhi syarat (2000-50000 cPs) dan tipe krim M/A. Hasil pengujian aktivitas antibakteri Staphylococcus aureus menunjukkan bahwa formula ke 3 menunjukkan aktivitas aktibakteri yang paling kuat dibanding formula lain dengan diameter daya hambat sebesar 3,73 mm. Dari hasil percobaan menunjukkan bahwa ekstrak daun mengkudu memiliki aktivitas antibakteri Staphylococcus aureus pada sediaan krim dengan sifat mutu fisik yang baik.
Pengembangan Formula Sabun Cair Anti Keputihan dari Ekstrak Daun Alamanda (Allamanda cathartica L.) dan Uji Aktivitasnya terhadap Candida albicans
Authors: Solihah Amalia , Yulianti Rika , Trisna Wulandari Winda , Indra Indra
Published: March 2024

This study aimed to formulate an anti-leucorrhoea liquid soap containing Allamanda cathartica L. leaf extract and to test its activity against Candida albicans. The maceration method was used to extract Allamanda cathartica L. leaves using 96% ethanol. The extract was used as a replacement for synthetic active ingredients in the anti-leucorrhoea liquid soap. After testing for minimum inhibitory concentration, the Allamanda cathartica L. leaf extract was formulated into formulas I, II, and III. The results of the organoleptic evaluation, pH, viscosity, foam stability, and microbial contamination showed that all three formulas met the predetermined requirements. The antifungal activity test on the preparation with 20% Allamanda cathartica L. leaf extract concentration showed the best results in formula III, with a inhibition diameter of 18.36 ± 0.38 mm against Candida albicans. The results of hedonic testing using the Kolmogorov-Smirnov analysis showed that overall, the panelists rated the shape, fragrance, and astringent impression positively, while on the parameter of foaminess, the panelists gave a negative rating. Keywords: anti-leucorrhoea liquid soap, Allamanda cathartica L. leaf extract, Candida albicans, antifungal activity.
POTENSI ANTIOKSIDAN SEDIAAN KRIM EKSTRAK ETANOL DAUN KLAPA SAWIT (Elaeis guineensis Jack.) DENGAN METODE DPPH (1,1-diphenyl-2-picrylhydrazyl)
Authors: Patimah Raudatul , Idawati Idawati , Ahdyani Risa , Indah Lestari Yulianita Pratiwi
Published: March 2024

Daun kelapa sawit (Elaeis guineensis Jack.) mengandung senyawa flavonoid yang merupakan golongan terbesar dari senyawa fenol yang berkhasiat sebagai antioksidan untuk melindungi tubuh dari pengaruh buruk yang dapat menyebabkan kerusakan kulit yang diakibatkan oleh radikal bebas. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi ekstrak etanol daun kelapa sawit terhadap potensi antioksidan pada sediaan krim ekstrak etanol daun kelapa sawit tipe m/a. Daun kelapa sawit diesktraksi dengan metode maserasi menggunakan pelarut etanol 96% menghasilkan ekstrak kental. Ekstrak etanol daun kelapa sawit dibuat dalam bentuk sediaan krim dengan variasi konsentrasi ekstrak etanol daun kelapa sawit yaitu FI (0,5%), FII (1%), dan FIII (1,5%). Sediaan krim dilakukan uji aktivitas antioksidan menggunakan metode DPPH dengan menghitung nilai IC50 dan AAI. Hasil pengujian aktivitas antioksidan dengan rata-rata nilai IC50 dan AAI yang diperoleh pada krim FI, FII, dan FIII berturut-turut yaitu 143,690 ppm dan 1,253; 115,754 ppm dan 1,555; dan 97,317 ppm dan 1,850. Formula krim terbaik yang memiliki potensi antioksidan yang kuat yaitu formula 3 dengan konsentrasi ekstrak etanol daun kelapa sawit sebesar 1,5%.
PEMANFAATAN LIMBAH BATANG POHON PISANG UNTUK PRODUKSI ASAM LAKTAT SECARA FERMENTASI DENGAN VARIASI KONSENTRASI INOKULUM Lactobacillus acidophilus
Authors: Abna Inherni Marti , Fauzi Eka , Harizal Harizal
Published: March 2024

Tanaman pisang merupakan tanaman yang banyak ditemukan di Indonesia. Salah satu bagian dari tanaman pisang adalah batang pohonnya. Batang pohon pisang merupakan bagian yang belum dimanfaatkan secara optimal, yang diambil buahnya lalu dibuang atau dikumpulkan pada suatu tempat sebagai limbah dan dibiarkan hingga busuk.  Batang pohon pisang memiliki kandungan gizi yang dapat digunakan sebagai sumber makanan bagi mikroba sehingga berkembang dengan baik. Kandungan gizi yang lengkap dari batang pohon  pisang ini dapat dimanfaatkan sebagai media fermentasi mikroba untuk menghasilkan asam laktat. Asam laktat merupakan hidroksikarboksilat yang memiliki banyak manfaat dalam  bidang industri seperti pangan dan farmasi. Tujuan pada penelitian ini adalah memanfaatkan limbah batang pohon pisang sebagai alternatif substrat dalam memproduksi asam laktat dengan bantuan bakteri Lactobacillus acidophilus secara fermentasi. Penelitian ini menggunakan metoda eksperimen dengan Rancangan Acak Lengkap (RAL) dengan tiga perlakuan dan tiga ulangan. Waktu fermentasi terbaik bagi  Lactobacillus acidophilus dalam memproduksi asam laktat ditentukan berdasarkan kurva pertumbuhan selama 24 jam dengan pengukuran optical density (OD) pada panjang gelombang 600 nm. Fermentasi dilakukan pada suhu 37oC dengan kecepatan agitasi 150 rpm.  Hasil penelitian menunjukan bahwa 20 jam merupakan waktu fermentasi terbaik. Produksi asam laktat oleh Lactobacillus acidophilus dilakukan dengan menggunakan konsentrasi inokulum 10%, 25%, dan 50%. Penentuan kadar asam laktat menggunakan metode spektrofotometri UV-Vis dan penentuan kadar gula menggunakan metode sulfat fenol. Hasil penelitian menunjukkan bahwa 10 % merupakan konsentrasi inokulum terbaik yang menghasilkan asam laktat tertinggi sebesar 2,08 g/L dan  gula media sebesar 1,878 g/L dalam medium fermentasi
PENGARUH MADU HUTAN TERHADAP KADAR GULA DARAH MENCIT PUTIH (Musmuscullus) JANTAN YANG DIINDUKSI ALOKSAN
Authors: Kunaedi Aan , Aprianty Siska , Falya Yuniarti
Published: March 2024

Diabetes is a group of chronic metabolic diseases associated with disorders of carbohydrate, fat and protein metabolism. It is hoped that this research will enable the public and patients suffering from Diabetes Mellitus to use other medicines as alternatives, such as traditional medicines that utilize the natural potential that exists in Indonesia, such as the use of honey, the honey used is taken from the Kuningan area and has not yet been tested for the potential for supportive therapy for DM sufferers. lowers the patient's blood sugar levels. Even though honey contains sugar, people believe that honey can be used as a medicine to lower type 1 and type 2 blood sugar levels, so for this reason it is necessary to scientifically test the potential of honey to reduce blood sugar levels in DM patients. This study aims to determine the effect of honey on the blood sugar levels of male white mice (Mus musculus) induced by alloxan. The research used was an experimental method. The research results show that the difference in antidiabetic effects with the most effectiveness is the positive control (Glibenclamide 0.05%) namely 127.2 mg/dL followed by honey treatment group III (honey 42 mg/20g BW) namely 122.6 mg/dL. Honey has an antidiabetic effect in mice induced by alloxan at a dose of 42mg/20g BW which has the best reducing effect.
TINGKAT PENGETAHUAN KARYAWAN INSTALASI FARMASI RSUD SAYANG CIANJUR TENTANG BEYOND USE DATE (BUD) OBAT
Authors: Koerniawan Erie Satrio , Rosmiati Meiti
Published: March 2024

ABSTRAKMenggunakan obat yang salah dapat menjadi masalah bagi kesehatan tubuh. Obat yang salah merupakan obat yang tidak layak lagi digunakan baik dari stabilitasnya maupun dari fisiknya. Salah satu hal yang menjadi patokan apakah obat tersebut masih layak digunakan atau tidak adalah Expiration Date (ED) atau tanggal kadaluarsa yang merupakan batas waktu penggunaan obat setelah diproduksi oleh pabrik farmasi, sebelum kemasannya dibuka. Dalam dunia kefarmasian, ED obat setelah dibuka disebut Beyond Use Date (BUD). Penelitian ini dilakukan bertujuan untuk mengukur Paradigma Karyawan Instalasi Farmasi RSUD Sayang Cianjur tentang Beyond Use Date obat. Metode yang digunakan dalam penelitian ini adalah metode survey dengan memberikan kuisoner online kepada responden untuk mengisinya. Kuesioner yang diberikan berisi 20 pertanyaan diantaranya 11 pertanyaan untuk pengetahuan BUD berdasarkan aspek kognitif dan 9 pertanyaan lainnya merupakan pengetahuan BUD berdasarkan aspek afektif. Diantara 20 pertanyaan itu terdapat pertanyaan  berdasarkan bentuk sediaan.  Hasilnya yang diperoleh bahwa berdasarkan aspek  kognitif paradigma TTK dan Apoeker tentang BUD masuk dala kategori baik dengan persentase 82,9% dan berdasarkan aspek afektif paradigma TTK dan Apoteker tentang BUD juga masuk dalam kategori baik dngan persentase 89,3%. Untuk paradigma TTK dan Apoteker tentang BUD dalam aspek kognitif dan aspek efektif berdasarkan bentuk sediaan masuk dalam kategori baik dengan rata-rata persentase secara keseluruhan 84,5%. Dengan akumulasi hasil tersebut Paradigma TTK dan Apoteker tentang Beyond Use Date (BUD) obat masuk dalam kategori baik
PENETAPAN KADAR FENOLIK DAN FLAVONOID TOTAL EKSTRAK ETANOL BATANG BAJAKAH TAMPALA (Spatholobus littoralis Hassk.)
Authors: Hidayatullah Muhammad , Rakhmatullah Aditya Noviadi , Perdana Dheny
Published: March 2024

Bajakah Tampala (Spatholobus littoralis Hassk.) merupakan tanaman asli Kalimantan yang berpotensi sebagai obat tradisional. Beberapa penelitian membuktikan bahwa Bajakah Tampala memiliki senyawa metabolit sekunder yakni fenol dan flavonoid yang berperan menghasilkan aktivitas seperti antioksidan, antibakteri, antitrombotik, antivirus, antialergi, antikanker dan antiinflamasi. Tujuan penelitian ini adalah penetapan kadar fenolik total dan flavonoid total dan dari ekstrak etanol 70% batang Bajakah Tampala. Metode ekstraksi yang digunakan adalah maserasi dengan pelarut etanol 70%. Analisis kualitatif senyawa kimia dengan skrining fitokimia fenol dan flavonoid. Penentuan kadar fenolik total dan flavonoid total dilakukan menggunakan Spektrofotometer UV-Vis. Hasil penelitian ini diperoleh rendemen ekstrak etanol 70% batang Bajakah Tampala sebesar 3,25%. Hasil identifikasi senyawa fenol dan flavonoid didapatkan ekstrak etanol 70% batang bajakah Tampala positif mengandung senyawa fenol dan flavonoid. Hasil uji kuantitatif kadar fenol total diperoleh sebesar 11.140 mgGAE/g atau 1.114% dan kadar flavonoid total diperoleh sebesar 32,59 mgQE/g atau 3,259%. Berdasarkan hasil tersebut dapat disimpulkan bahwa kadar fenol total lebih tinggi dibandingkan kadar flavonoid total.
FORMULASI DAN UJI FISIK SEDIAAN LIP BALM KOMBINASI SARI BUAH NAGA MERAH (Selenicereus monacanthus) DAN MINYAK ZAITUN (Oleum olivea)
Authors: Fatwami Esti Febri , Diani Miftah Cahya , Royani Sri
Published: March 2024

Recently, people are more inclined to choose cosmetics with natural ingredients because people believe that natural ingredients will be safe to use than cosmetic products that contain harmful chemicals. This is the main reason for making this lip balm using natural ingredients such as red dragon fruit juice and olive oil as cosmetics that are safe to use and environmentally friendly. The research method was experimental. 150 grams of fresh red dragon fruit juice was used and after the extract was made, the yield was 100 grams. After the preparations were made, physical tests and stability tests were carried out. The organoleptic test results for the lip balm preparations experienced a color change due to oxidation, the homogeneity test obtained homogeneous lip balm preparations, and the pH test for the lip balm preparations for the three formulasitions was in the range of 5-7 both before and after the stability test, the melting temperature test for the preparations before the stability test the results obtained were 65 degrees Celsius and after testing the stability of 60 degrees Celsius, the adhesion test was in the range above 60 seconds after testing the stability of the adhesion increased, the spreadability test was in the range of 5-5.8 and after testing the stability the spreadability increased. Lip balm from red dragon fruit (Selenicereus monacanthus) has been made unstable in color because after 2 weeks of storage the color of the lip balm fades and from the three formulasitions the difference in the concentration of the emulsifier does not affect the smell and color of the lip balm, but only affects the consistency of the preparation lip balms. Keywords: Lip balm, red dragon fruit, olive oil, temperature, smell
Profil Pengetahuan Mahasiswa Baru Terkait Antibiotik: Sebuah Tinjauan Awal Studi Cross Sectional
Authors: Nurlatifah Aulia , Rahmawati Rahmawati , Salasanti Citra Dewi , Hamidah Mida
Published: March 2024

Abstract Knowledge of antibiotic use in new students at the Faculty of Pharmacy is important given their role as future health workers. In this context, a quantitative descriptive study was conducted to measure students' understanding of antibiotic use. Questionnaire was the tool used in this cross sectional study. which contains ten questions. Knowing the level of knowledge of freshmen is the purpose of this study. The respondents involved were active new students at the Faculty of Pharmacy at the time of data collection. The results of this study showed that most students had a good understanding of six of the ten questions asked. Questions number 1, 5, 6, 7, 9, and 10 resulted in good knowledge regarding the use of antibiotics. However, there was sufficient knowledge in questions 2 and 8, indicating the need for a deeper understanding of the function of antibiotics. Furthermore, the unsatisfactory category is related to question number 3, which shows a low level of knowledge on the use of antibiotics. Keywords: Pharmacy students, Knowledge, Antibiotics.  Abstrak Pengetahuan tentang penggunaan antibiotik pada mahasiswa baru di Fakultas Farmasi merupakan hal yang penting mengingat peran mereka sebagai calon tenaga kesehatan. Dalam konteks ini, studi deskriptif kuantitatif dilakukan untuk mengukur pemahaman mahasiswa terhadap penggunaan antibiotik. Kuesioner merupakan alat yang digunakan dalam penelitian ini secara cross sectional. yang berisi sepuluh pertanyaan. Mengetahui Tingkat pengetahuan mahasiswa baru merupakan tujuan dari penelitian ini. Responden yang terlibat adalah mahasiswa baru aktif di Fakultas Farmasi pada saat pengambilan data. Dari hasil penelitian ini memperlihatkan  bahwa dari sebagian besar mahasiswa memiliki pemahaman yang baik terkait enam dari sepuluh pertanyaan yang diajukan. Pertanyaan nomor 1, 5, 6, 7, 9, dan 10 menghasilkan pengetahuan yang baik terkait penggunaan antibiotik. Namun, terdapat pengetahuan yang cukup pada pertanyaan nomor 2 dan 8, menandakan perlunya pemahaman lebih dalam terkait fungsi antibiotik. Selanjutnya kategori yang kurang memuaskan adalah terkait pertanyaan nomor 3, yang menunjukkan tingkat pengetahuan yang rendah terhadap penggunaan antibiotik Kata kunci: Mahasiswa farmasi, Pengetahuan, Antibiotik
S SOSIALISASI PENCEGAHAN DAN PERAWATAN JERAWAT BAGI SISWA SMA NEGERI 1 NAMORAMBE
Authors: Rahmi Sofia -
Published: March 2024

SMA Negeri I Namorambe is a high school located in Deli Serdang district, North Sumatra province. Most  students often sweat and rarely clean their bodies, especially their faces. These students also often eat unhealthy snacks, so  their hormonal conditions, especially growth-related problems, become unstable. As a result, health problems often arise, including acne. Delegates of the Faculty of Pharmacy, Deli Husada  Deli Tua Institute of Medicine and Medistra  Lubuk Pakam Institute of Medicine organized  socialization of acne prevention and treatment for high school students. Through socialization, it is hoped that students can further improve personal hygiene, especially facial hygiene, and maintain a healthy lifestyle in the environment.
SAKU SEHAT MILENIAL : EDUKASI PEMANFAATAN PARE (Momordica charantia L.) DAN BUNGA ROSELLA (Hibiscus sabdariffa L.) DALAM MENGOBATI DIABETES DI MADRASAH ALIYAH SWASTA AL-WASHLIYAH 30 BINJAI
Authors: Syafitri Anggun , Rahmi Sofia , Hayati Silmi , Tamba Agnes Clara , Br Barus Lidia Klorida
Published: March 2024

Diabetes melitus merupakan penyakit gangguan metabolik yang disebabkan oleh gagalnya organ pankreas dalam memproduksi hormon insulin secara memadai. Terapi farmakologi diabetes melitus saat ini masih terbatas pada penggunaan obat-obatan seperti hipoglikemik oral (OHO) dan masyarakat yang menderita diabetes sebagian besar melakukan swamedikasi dengan obat tradisonal yang digunakan bersamaan dengan obat antidiabetes sintesis. Salah satu contoh tanaman yang dapat menurunkan kadar glukosa darah adalah buah pare dan bunga rosella yang memiliki kandungan flavonoid untuk menurunkan glukosa darah dengan cara meningkatkan sensitivitas sel terhadap insulin dan merangsang pelepasan insulin pada sel β pancreas. Tujuan dari kegiatan ini adalah untuk memberikan edukasi kepada siswa  Madrasah Aliyah Swasta Al-Washliyah tentang obat antidiabetes yang berasal dari bahan alam yaitu buah pare dan bunga rosella. Setelah mengikuti kegiatan ini peserta memiliki pengetahuan yang baru tentang cara pengolahan bahan alam seperti buah pare dan bunga rosella sebagai terapi pengobatan diabetes melitus yang aman dan efektif.
Edukasi Penggunaan Obat Simptomatik Dan Antibiotik Terhadap Suatu Penyakit Kepada Siswa SMAS Primbana Medan
Authors: Simorangkir Delisma , Sanjaya Angga
Published: March 2024

This article is an analysis of education regarding the use of symptomatic drugs and antibiotics for a disease for SMAS Primbana Medan students. Education on the use of symptomatic drugs and antibiotics for a disease is an important thing to educate students and the public to provide appropriate information on the good and appropriate use of symptomatic drugs and antibiotics, because of the high number of side effects in the use of symptomatic drugs and antibiotics in the community, one One side effect that occurs when using symptomatic drugs is stomach ulcers and when using antibiotics, namely antibiotic resistance. PKM activities are carried out in three stages, namely the production implementation stage, the evaluation stage and the reporting stage. PKM activities are useful for increasing public health knowledge and standards where students can participate in educating friends, family and the environment about when to use symptomatic drugs and antibiotics and when to stop using them.
EDUCATION ON THE BENEFITS OF LEMONGRASS (cymbopogon citratus) LEAF EXTRACT AS A ANTIBACTERIAL MOUTHWASH
Authors: Fahdi Firdaus , Sari Herviani , Sembiring Bunga Mari
Published: March 2024

Dental and oral health problems are a serious problem. Even though it looks simple, maintaining oral and dental hygiene is important to maintain quality of life. Dental caries is the main cause of dental problems, this occurs due to an individual's lack of knowledge in maintaining the cleanliness of their teeth and mouth. Using lemongrass as an alternative mouthwash is another option in an effort to maintain oral hygiene. This service activity was carried out at Sembiring Deli Tua Hospital targeting participants from children to adults. Activities are carried out in three stages, namely the preparation stage, implementation stage and feedback. After participating in the service activities, it was discovered that there was an increase in participants' understanding and knowledge in maintaining oral and dental hygiene.
Penyuluhan sebagai Upaya Peningkatan Pengetahuan Hipertensi pada Lansia Di Klinik Tiara Medistra Tembung
Authors: Siregar Julahir Hodmatua , Batubara Saiful
Published: March 2024

Hypertension is a disease that is often found in the community, especially in the elderly. This disease can cause complications so it needs to be handled properly.  One way to achieve this goal is by counseling. The purpose of this community service activity is so that the community, especially the elderly, has, understands and maximizes knowledge about hypertension. The method carried out is in the form of two-way counseling using exposure with power points containing hypertension material and questionnaires before and after counseling. The target of this activity is the community/elderly patients at Tiara Medistra Clinic totaling 25 people. The implementation will be carried out on Sunday, June 22, 2023, in the clinic waiting room. After the counseling activity, a questionnaire was carried out which showed an increase in public knowledge about hypertension. The increase in knowledge is expected to make the community, especially the elderly, better able to apply this knowledge to daily life.
EDUKASI PENERAPAN SISTEM INFORMASI MANAJEMEN PUSKESMAS (SIMPUS) DALAM PELAYANAN PUBLIK DI PUSKESMAS DELI TUA
Authors: Sembiring Ripando , Malau Pitto Pratiwi , Surbakti Desmayanti , Sembiring Mega Claudia
Published: March 2024

The research objective of the Implementation of the Community Health Center Management Information System (Simpus) on Patient Satisfaction at the Deli Tua Community Health Center in 2023 is to analyze the influence of health service quality on outpatient patient satisfaction. In the Deli Tua Community Health Center working area, JKN participants use quantitative observation and cross-sectional analytical methods, investigating how and why this phenomenon occurs. Then analyze the dynamics of the correlation of phenomena or risk factors and influence factors from the results of the research carried out. Analysis of the relationship between the implementation of the Community Health Center Management Information System (Simpus) and patient satisfaction with p-value (0.002); compared to 0.05, it can be concluded that Ha is accepted with Ho, which means there is a relationship between the implementation of the Puskesmas management information system and the patient satisfaction of the Deli Tua Health Center, and the decision to study the implementation of the Puskesmas Management Information System (Simpus) has an effect on the patient satisfaction of the Deli Tua Health Center. conclusion on the implementation of information at the Deli Tua Health Center.