bluuebunny/crossref_metadata_2025 huggingface dataset:
Curcumin regulates intracellular calcium release and inhibits oxidative stress parameters, VEGF, and caspase-3/-9 levels in human retinal pigment epithelium cells
Authors: Bardak H , Uğuz AC , Bardak Y
Published: December 2017

In this study, we aimed to observe whether curcumin (cur), a polyphenolic compound derived from the dietary spice turmeric, a yellow substance obtained from the root of the plantCurcuma longa Linn, has any protective effect against blue light irradiation in human retinal pigment epithelium (ARPE-19) cells. For this purpose, we evaluated the intracellular calcium release mechanism, poly ADP ribose polymerase (PARP), procaspase-3/-9 protein expression levels, caspase activation, and reactive oxygen species levels. ARPE-19 cells were divided into four main groups, such as control, cur, blue light, and cur + blue light. Results were evaluated by Kruskal–Wallis and Mann–WhitneyUtests aspost hoctests. The cells in cur and cur + blue light samples were incubated with 20 μM cur. Blue light exposure was performed for 24 h in an incubator. Lipid peroxidation and cytosolic-free Ca2+[Ca2+]iconcentrations were higher in the blue light exposure samples than in the control samples; however, their levels were determined as significantly lower in the cur and cur + blue light exposure samples than in the blue light samples alone. PARP and procaspase-3 levels were significantly higher in blue light samples. Cur administration significantly decreased PARP and procaspase-3 expression levels. Reduced glutathione and glutathione peroxidase values were lower in the blue light exposure samples, although they were higher in the cur and cur + blue light exposure samples. Caspase-3 and -9 activities were lower in the cur samples than in the blue light samples. Moreover, vascular endothelial growth factor (VEGF) levels were significantly higher in the blue light exposure samples. In conclusion, cur strongly induced regulatory effects on oxidative stress, intracellular Ca2+levels, VEGF levels, PARP expression levels, and caspase-3 and -9 values in an experimental oxidative stress model in ARPE-19 cells.
Young Sikhs in a Global World: Negotiating Traditions, Identities and Authorities, edited by Knut A. Jacobsen and Kristina Myrvold
Authors: Nesbitt Elearnor
Published: December 2017

Young Sikhs in a Global World: Negotiating Traditions, Identities and Authorities, edited by Knut A. Jacobsen and Kristina Myrvold, Farnham: Ashgate, 2015. xv + 293 pp., £70.00 (hb). ISBN 978-1-472-45696-0 (hb).
Autologous Stem Cell Transplantation in Elderly Lymphoma Patients in Their 70s: Outcomes and Analysis
Authors: Sun Lova , Li Shuli , El-Jawahri Areej , Armand Philippe , Dey Bimalangshu R. , Fisher David C. , Jacobsen Eric D. , Jacobson Caron A. , LaCasce Ann S. , McAfee Steven L. , Spitzer Thomas R. , Chen Yi-Bin , DeFilipp Zachariah
Published: December 2017

Background

High-dose chemotherapy and autologous stem cell transplantation (ASCT) can offer durable remission in many patients with relapsed or high-risk lymphoma. However, elderly patients are often not considered ASCT candidates based on age alone.

Subjects, Materials, and Methods

A retrospective analysis of patients ≥70 years of age with a diagnosis of Hodgkin or non-Hodgkin lymphoma receiving ASCT between 2000 and 2016 at two partner institutions was performed. Clinical data were extracted from institutional databases and individual medical records. Multivariate analysis was performed to examine the association of clinical variables with transplant outcomes.

Results

One hundred seven patients were identified. Median age at transplant was 72 years (range, 70–79). The most common lymphoma subtype was diffuse large B-cell (n = 63, 59%). Median time to neutrophil and platelet engraftment were 10 and 12 days, respectively. With a median follow-up for survivors of 20 months following ASCT (range, 6 months to 13.1 years), estimates for 2-year progression-free survival and overall survival were 58% (95% confidence interval [CI], 48%–67%) and 65% (95% CI, 55%–74%), respectively. Two-year estimate for relapse was 34% (95% CI, 25%–44%) and nonrelapse mortality (NRM) was 7% (95% CI, 3%–14%). Multivariate analysis showed that more recent date of transplant was associated with lower NRM. The Hematopoietic Cell Transplantation-Comorbidity Index score was not predictive of NRM in this data set (high-risk vs. low-risk, hazard ratio 3.45, p = .065).

Conclusion

Eligibility for ASCT should be an individualized decision, and age should not be an absolute contraindication to ASCT in healthy elderly patients with lymphoma.

Implications for Practice

Although high-dose chemotherapy and autologous stem cell transplantation (ASCT) can offer durable remission in many patients with relapsed or high-risk lymphoma, elderly patients are often not considered candidates due to concern for excess toxicity and mortality. This retrospective study showed favorable transplant outcomes, including survival and toxicity, in a large cohort of lymphoma patients over 70 years of age who underwent ASCT. Eligibility for ASCT should be an individualized decision, and age should not be an absolute contraindication to ASCT in healthy elderly patients with lymphoma.
Massively Parallel Qubit DNA Quantification Using OpenTrons v4
Authors: Huang Suzy
Published: December 2017

Measurement of DNA can be done using two broad methods (Spectrophotometric or Fluorometric). Qubit is a fluorometric method and uses a double stranded DNA specific dye. Therefore the sensitivity is higher and impurities like RNA or nucleotides in the sample will not affect thequantification as it would in spectrophotometric methods like a Nanodrop.The Qubit is first calibrated using two standards. To make a measurement,199ul of buffer +1ul of dye + 1ul of sample is added to a qubit tube, which is inserted into the instrument.Here, we use OpenTrons to prepare samples for qubit measurement.It also saves time byrequiring only one initial calibration for each container. It uses p1000 to distribute master mix and p10 to distribute unique samples.
Targeted ballet program mitigates ataxia and improves balance in females with mild-to-moderate multiple sclerosis v1
Authors: M. Scheidler Andrew , Kinnett-Hopkins Dominique , C. Learmonth Yvonne , Motl Robert , Lopez-Ortiz Citlali
Published: December 2017

Experimental procedural checklist. Detailed description of sample exercises with images. Example class outline for the TBP that includes chair, barre, and across the floor exercises.
A biografia em sua dimensão argumentativa: o fazer-fazer
Authors: Abreu-Aoki Raquel Lima de
Published: December 2017

O Estado Novo foi fértil na reprodução de textos contendo apologias ao regime e ao estadista Getúlio Vargas. Tal estratégia visava a difusão dos valores e ideais estadonovistas. Dentre esses materiais, selecionamos a biografia Getúlio Vargas para crianças, de autoria de Alfredo Barroso, com o objetivo de analisarmos a construção das imagens de Vargas e compreendermos o ideário daquela conjuntura. Ancoramo-nos na teoria Semiolinguística de Patrick Charaudeau, que nos ajudou a compreender: as instâncias de produção do discurso; os parceiros da troca linguageira e seus estatutos; a finalidade do ato comunicativo e as circunstâncias materiais nas quais se realiza o ato linguageiro. 
Resenha de Renaissances de la Rhétorique. Perelman aujourd’hui, de Angenot, Bernier & Côté
Authors: Lima Helcira Maria Rodrigues de
Published: December 2017

Trata-se da resenha da obra Renaissances de la rhétorique. Perelman aujourd’hui, organizada por Marc Angenot, Marc André Bernier e Marcel Côté. Tal publicação é fruto de reflexões empreendidas por pesquisadores de diferentes universidades acerca da obra de Perelman, no Colóquio realizado na Universidade de Quebec em Trois-Rivières, em 2012. O livro é constituído de cinco capítulos, sendo quatro destes compostos de dois textos e um deles de três, além de um prefácio e um posfácio, em um total de 13 textos. A partir de diferentes lugares de enunciação, os autores atestam a importância da herança perelmaniana dando ênfase a noções-chave que perpassaram as reflexões do filósofo e se assentaram, em especial, no Tratado da Argumentação: a Nova retórica, livro que constitui o ponto de partida para os debates.
Научно-методические подходы к формированию системно-интуитивного мышления студентов-юристов колледжа на занятиях иностранного языка
Authors: Картакаева Эльмира Анваровна
Published: December 2017

В статье рассмотрены вопросы формирования личности, обладающей системно-интуитивным мышлением, на занятиях иностранного языка студентов среднего профессионального образования юридического направления. Сделаны выводы о методах, способствующих положительной динамике развития системно-интуитивного мышления студентов.
Evaluation of associated risk factors of near miss obstetrics cases at B.P. Koirala Institute of Health Sciences, Dharan, Nepal
Authors: Khadka Madan , Uprety Dhruba Kumar , Rai Rubina
Published: December 2017

Background: In 2011, around 273,465 women died worldwide during pregnancy, childbirth or within 42 days after childbirth. Near-miss is recognized as the predictor of level of care and maternal death. The objective of the study was to evaluate the associated risk factors of near miss obstetric cases.Methods: A prospective observational study was done from August 1, 2014 to July 30, 2015 in Department of Obstetrics and Gynecology at BPKIHS hospital, tertiary care hospital in Eastern Nepal, Dharan. Case eligible by 5 factor scoring system and WHO near miss criteria were evaluated. Risk factors included severe hemorrhage, hypertensive disorders, complication of abortion, ruptured uterus, medical/surgical condition and sepsis.Results: A total of 9,727 delivery were attended during the study period from August 2014 to July 2014. There were 6307 (71.5%) vaginal delivery and 2777 (28.5%) caesarean section and 181 perinatal death with total of 9,546 livebirth. 162 near miss and 16 maternal death occurred during the study. Maternal near miss rate of 16.6 per 1000 live birth, Women with life-threatening conditions of 172, Severe maternal outcome ratio of 18.64, Maternal near-miss: mortality ratio: 10.1:1, Mortality index: 8.98%. Risk factors were obstetric hemorrhage 27.8%, abortion/ectopic 27.2%, eclampsia 16%, medical/surgical condition 14.8%, sepsis 13.6%, severe preeclamsia 11.1%, ruptured uterus 3.1%, and molar pregnancy 1.9% and cardiovascular and coagulation dysfunction as a major life-threatening condition and sepsis (25%) was the major cause of mortality.Conclusions: Haemorrhage and hypertensive disorders are the leading causes of near miss event. Evaluation of associated risk factor can be potential tool for reduction of maternal morbity and mortality.
Managing bile duct injuries sustained during cholecystectomies
Authors: Srivastava Vijay Prakash , Agarwal Shwetank , Agarwal Ajai , Sharan Jagadamba
Published: December 2017

Background: Medical science is a blend of Art and Science. Technology evolved conceived presumably to improve the medical science. Increasing incidence of bile duct injury during laparoscopic cholecystectomies proved otherwise. Multiple factors e.g. cognitive psychology, laparoscopic environment and no proper algorithms to manage, factor may be responsible for these results. To understand properly the mystique, we under took this study.Methods: This study was conducted on 200 cases which underwent laparoscopic cholecystectomies. 12 cases developed bile duct injury during laparoscopic cholecystectomies and 10 cases of bile duct injury sustained through open cholecystectomies were studied in detail results noted and analyzed.Results: All these cases 12/200 laparoscopic cholecystectomy, 10/200 open cholecystectomies were followed up, sign and symptoms noted, USG studies, ERCP stenting, sphincterotomy studies reviewed and sequence of management underlined.Conclusions: Early realisation of bile duct injuries remains the hall mark of she success. Even in cases detected late, conservative procedure and stenting with or without sphincterotomy given relief in number of cases. Finally, if surgery is contemplated Roux-Y-biliary enteric procedure gives much better results.
Peptic ulcer perforation in young Indians the causation and the trend
Authors: Sabhnani Geeta , Sindhu Akula Nyna
Published: December 2017

Background: Peptic ulcer perforation is the commonest surgical emergencies in India. Recent emergency surgical procedures show an increasing trend in peptic ulcer perforation surgery in young adults. This study is carried out with an aim to understand the trend, causation and complications of peptic ulcer perforation in young Indians.Methods: A prospective observational study of young adult Indian patients operated for emergency peptic ulcer perforation for a 3 years period from January 2014 to January 2017 was carried out. The incidence, causative factors and the complications were analyzed.Results: In study of 150 patients, maximum incidence of 42.85% was seen in age group of 21 to 30 years that is young adults. 80% of them were males. 59% patients had blood group O. Association with smoking and alcoholism was seen in about 64% and 66.6% respectively. In about 13.33% there was an association seen with history of NSAID / steroid ingestion / treatment with proton pump inhibitors or H2antagonists.The duodenal perforation was found in 84.66%. In 90% the perforation was less than 1cm.Wound infection was the commonest complication among all patients. Mortality was seen in 3.33%.Conclusions: Peptic ulcer perforation shows increasing incidence in young adult males. The increased incidence shows association to smoking, alcoholism, irregular food habits, use of NSAIDS/steroids and overall stressed lifestyle.
Role of dilatation of intramural ureter in patients with lower urinary tract symptoms (LUTS) in UVJ and pre UVJ calculus: an observational study
Authors: Krishnappa Narasimhaiah , Khan Asif , Sakranaik Saraswathi
Published: December 2017

Background: Various literature sources describe three narrowest anatomic spots in the ureter as the most potential points for ureteric calculi to form and these are: the pelvi-ureteric junction (PUJ), the point where the ureters cross over the iliac vessels and the ureterovesical junction (UVJ).Methods: This study included patients who presented with symptomatic obstructing ureteric calculi and who required uretero renoscopic lithotripsy (URSL). The procedure was selected according to stone size, location and degree of impaction.Results: Of the total of 100 patients, 43 were females and 57 were males. 69 patients had Lower Urinary Tract Symptoms and 31 patients had no Lower Urinary Tract Symptoms with the calculi. The age of the patients ranged from 17 years to 65 years and the stone size ranged from 7mm to 15mm. Lower ureteric calculi with LUTS are good indicators.Conclusions: We can approach lower ureteric calculi without use of dilators or 6/7.5ureteroscope in patients with LUTS.
Outcome of laparoscopic total extraperitoneal approach with direct dissection and mesh hernioplasty in the treatment of inguinal hernias
Authors: Hisham Yousef , Ranjith Mannarakkal , Nabeel Thommil Padinjarenalakath , Sidhic Kummankandath Abbas
Published: December 2017

Background: Laparoscopic inguinal hernia repair has become increasingly popular as an alternative to open surgery. Aim: To evaluate total extraperitoneal repair with direct telescopic dissection and mesh hernioplasty for inguinal hernias.Methods: This study was conducted at General Surgery department the period of 1 year on 30 patients having inguinal hernia.Results: This prospective study included 30 adult patients with primary unilateral inguinal hernia, all of them were males. Age of study patients ranged from 22 to 64 years old. Intraoperatively, 6 patients were presented to have direct inguinal hernia (20%) while 21 patients had indirect inguinal hernia (70%). In 3 patients, combined direct and indirect hernia defects were present (10%). Mean operative time was 99.30±25.13 min. Mean time for analgesia was 3.62±1.57 days. Hospital stay mean was 1.43±0.62 days. The mean time until return to work was 14.1±3.13 days, the mean time of follow up was 7.1±2.2 months. Intra operatively 5 (15%) and post operatively 8 (26.6%)complications were observed.Conclusions: Laparoscopic TEP repair is an excellent alternative to open preperitoneal repair of inguinal hernia. Complication rate was average with other studies while there was no hernia recurrence during the period of follow up.
Role of scoring system in prediction of difficult laparoscopic cholecystectomy
Authors: Rhezhii Delie , Goyal Vikas , Nagpal Nitin , Nemma Shobhit Kumar , Gupta Monica
Published: December 2017

Background: One of the most common reasons for admission to hospital is cholecystectomy and it has a mortality rate of 0.45% to 6%. Many risk factors have been found to be associated laparoscopic cholecystectomy that make it difficult like advance age, male gender, fever, obesity, previous abdominal surgeries, thick gall bladder lining, distention of bladder, presence of gall stones. There have been different scoring systems in literature that determine the risk of conversion to open cholecystectomy. The aim of present study is to determine the role of scoring system in predicting difficult laparoscopic surgery.Methods: The present prospective study was conducted for a period of 1 year in the Department of Surgery at Guru Gobind Singh Medical College, Faridkot, Punjab. The study included all the patients with symptomatic gall stones reporting to the OPD of the hospital. Patients were categorized into two groups after the surgery. Group I included patients who underwent successfully laparoscopic cholecystectomy and group II included those who were converted into an open case. In this study all the entities were provided with a score. Patients with score less than 4 were grouped as difficult. At the end of the study all the data were analyzed to see how scoring system can predict which patients will have easy or difficult laparoscopic cholecystectomy based on postoperative scoring. All the data was recorded in a tabulated form and analyzed using SPSS software.Results: The present prospective analytical study involved 112 subjects; out of these 94 were males and 18 females. The mean age of subjects was 48.2±3.7 years. There were 98 patients in Group I and 8 patients in group II who had didn’t show presence of peri cholecystic fluid. There was 1 patient in Group I and 5 patients in group II who had peri cholecystic fluid on ultrasound. There were 104 subjects with gall was thickness less than 4 mm. There were 95 patients in Group I and 9 patients in group II who had who had who had bladder wall thickness of less than 4 mm.Conclusions: The scoring tool evaluated in our study is useful in evaluating the risk of conversion of laparoscopic cholecystectomy into open cholecystectomy.
A prospective study to determine the role of routine prophylactic oral calcium and vitamin D supplements in prevention of transient hypocalcaemia after total and near total thyroidectomy
Authors: Nair Kiran Sukumaran , Gamalial Jose , P. S. Rajesh
Published: December 2017

Background: Transient hypocalcaemia is a frequent complication after total thyroidectomy, and the symptoms are very distressing for the patients. This study is a prospective cohort study to assess the effectiveness of routine postoperative oral calcium and vitamin D supplementation in post thyroidectomy hypocalcaemia.Methods: 135 patients undergoing near total or total thyroidectomy were divided into two groups, exposed and unexposed, based on post-operative calcium and Vitamin D administration. Both groups were followed up at day 3, at discharge and 2 weeks post operatively for the development of hypocalcaemia.Results: Common age group was 31-40 years in both groups. The mean corrected pre-operative serum calcium was 9.06±0.43mg/dl for the exposed and 9.2±0.62mg/dl for the unexposed group (p = 0.12). The mean corrected calcium levels, on third post op day was 8.9±0.61mg/dl for exposed and 8.5±0.69mg/dl for unexposed group p = 0.001), on day of discharge was 9.2±0.56mg/dl for exposed and 9.0±0.48mg/dl for unexposed group (p = 0.019), and at 2 weeks follow-up was 9.5±0.51mg/dl for exposed and 9.2±0.63mg/dl for unexposed group (p = 0.002). Incidence of clinical symptoms of hypocalcaemia in the exposed group was 5.1% and in the unexposed group was 25.9%. Majority of these patients had transient hypo-calcaemic symptoms in the 48-72hr time period after surgery in both the groups.Conclusions: Routine prophylactic oral calcium and Vitamin D supplementation is effective in preventing transient hypocalcaemia following total or near total thyroidectomy.
Causative factors of deep vein thrombosis of lower limb in Indian population
Authors: Khadilkar Reina , Bhatnagar Shubhi P. , Dave Preet
Published: December 2017

Background: Deep vein thrombosis refers to the formation of an abnormal coagulum within the deep venous system. An accurate diagnosis of DVT is extremely important to prevent potentially fatal acute complications of pulmonary embolism (PE) and long-term complications of post phlebitis syndrome and pulmonary hypertension. There are many causative factors for DVT.Methods: This was a prospective study where 50 cases of DVT were admitted in this centre. Patients were evaluated in terms of causative factors of DVT. These were previous history of DVT, immobility, surgery, smoking, obesity and drugs. Age and gender comparisons were also done. The most common causes were recorded.Results: The most common cause was found to be immobility and post-surgery immobilization which constituted 90 % of the patients in the study. Advanced age and male gender showed a higher incidence of DVT.Conclusions: Early identification of the causes and the risk factors in the development of DVT can reduce the burden of the disease and contribute to its prevention and management.
Follicular variant of ameloblastoma mandible reconstructed with free fibula: a case report
Authors: Kaur Ramandeep , Arora Vipin , Sharma Sonal
Published: December 2017

Ameloblastoma is a tumor of odontogenic epithelium arising from remnants of dental lamina. It is a benign tumor but locally invasive affecting mandible more than maxilla. Ameloblastomas grow into the bone and soft tissues causing facial disfigurement and facial deformities. Treatment is surgical. We present a case report of 60 year old male with swelling in jaw, biopsy revealed ameloblastoma. Anterior segmental mandibulectomy was done and reconstructed with fibular flap which restored both function and aesthetic appearance.
A study to assess the knowledge and practice of initiation of immunisation in mothers of low birth weight Neonatal Intensive Care Unit (NICU) graduates in a tertiary care centre
Authors: Gandhi Prachi Shailesh , Dande Vaidehi
Published: December 2017

Background: Premature and low birth weight (LBW) infants are susceptible to infections including those which are preventable. The coverage of immunization in this subset of babies is poor. The present pilot study was an attempt to identify factors which lead to delay in initiation of immunization in this vulnerable group. The objective of this study was to assess knowledge and practice of initiation of immunization in mothers of low birth weight (<2 Kg) NICU graduates and effect of specific counselling on the practice of immunization. Methods: A prospective pilot study was done between 1st April to 30th June 2016. In the first phase, mothers of LBW and preterm babies were assessed using 2 validated questionnaires on discharge and in High-Risk OPD. In the second phase, a different set of mothers were assessed similarly but counseled specifically by the principal investigator to initiate immunization irrespective of the weight and chronological age. Results were interpreted using the Fischer Exact test, Independent T-test and McNemar.Results: Among 30 babies in the study, 16 (53.33%) were immunized, of which 6 (37.5%) babies had a timely initiation. Birth weight and duration of NICU stay significantly affected the time of initiation of immunization. There was a significant lack of knowledge in mothers of non-immunized babies. When counseled by the primary investigator, 85.8% and 50% of mothers agreed that immunization can be initiated at birth and even if birth weight is less than 2 kg respectively.Conclusions: Immunization initiation was delayed in most of the preterm and low birth weight babies. Post counseling a favorable change was observed in mothers’ knowledge but not practice.
Konsep Life Skills dalam Pembelajaran Bahasa Arab di Madrasah
Authors: Mas'ud Muhammad
Published: December 2017

This research uses qualitative descriptive approaching method and use study case research type. The data obtained from primary and secondary data sources, which data collection techniques are observation, interview, and documentation. The results of the research stated that in the life skill education design in the Arabic Language Learning at MI NU Tamrinut Thullab Undaan Kudus are: The aspects of life skills that will be developed are integrated and will be a part of the basic competencies that must be pursued accomplished with the achievement skills derived from the substance of the subject matter of Arabic Language Learning which is outlined into Prota, Promes, SK and KD Mapping, Syllabus, and RPP form. Implementation of life skill education in Arabic Language Learning at MI NU Tamrinut Thullab Undaan Kudus; according to the physiological and psychological level of students at the MI, it is emphasized on efforts to develop generic skills such as personal skills and social skills. While the supporting factors in the Life Skill Education implementation in Arabic Language Learning at MI NU Tamrinut Thullab Undaan Lor Undaan Kudus are: (1) Madrasah Religious Program; (2) Self Development Program in Madrasah; (3) Madrasah Cultural Development Program; (4) Most students have been studied at Diniyyah / TPQ. Whereas, the obstacles factors in the life skills education implementation in Arabic Language Learning at MI NU Tamrinut Thullab Undaan Lor Undaan Kudus are: (1) The lack of funds and facilities; (2) Educators are less motivated to be creative and innovative for using and developing learning strategies.
Varicose veins of the small pelvis and pelvic congestion syndrome. A differentiated approach: the choice of method of contraception, treatment, prevention
Authors: А. Н. Григоренко  , А. Б. Гордийчук
Published: December 2017

The article considers the main points that affect the quality of life of women with varicose veins of small pelvis with congestion and without it, in particular the use of hormonal methods of contraception, and also discussed the issues of diagnostics, prevention and treatment of these diseases. Algorithms of clinical tactics for conducting such patients are presented. Particular attention is focused on the features of the appointment of hormonal drugs in this category of women. You can determine the methods of treatment and avoid long-term unreasonable prescription of various medicine (especially hormones that will mask or worsen the course of the disease) if you select groups of women with varicose veins of the small pelvis without congestion and with it (reflux).Varicose veins of the small pelvis and pelvic congestion syndrome are conditions that require an interdisciplinary and differentiated approach. Symptoms of these conditions can be put on a mask of various gynecological, urological, traumatological diseases. Anatomical and physiological features of the structure of the veins and the regulation of their venous tone explain the possibility of forming a venous congestive syndrome in women. This can be due to two reasons: due to the violation of the outflow of venous blood or due to the obstruction of any vein of the ovary, any increase in intravascular pressure not controlled by the venous tone at the level of the pelvis.Varicose veins of the small pelvis and pelvic congestion syndrome remain unexplored until the end. There are no uniform standards for their diagnostics. Varicose veins of the small pelvis and pelvic congestion syndrome are different diseases which requiring an understanding of the mechanisms of their development and consequences. If a pelvic varicose veins are suspected, the first diagnostic test is usually ultrasound. Modern ultrasound technique can evaluate blood flow in various veins. To study the blood flow in the veins, laparoscopy, venography in combination with CT or MRI can also be performed.
Prediction of heavy degree of flow of menopausal disorders for women with hyperproliferative processes of reproductive system using a mathematical model
Authors: Л. І. Бутіна
Published: December 2017

Objective. Prognostication of heavy degree of flow of menopausal disorders in women with hyperproliferative processes of reproductive system.Materials and methods. For the exposure of factors, related to severity of flow of climacteric syndrome (CS) and estimation of degree of their influence on development of heavy degree of flow of menopausal disorders, the method of construction and analysis of multivariable mathematical models was utilized. The results of investigation of 19 indexes from 124 women aged 45 to 79 with menopausal disorders (climacteric syndrome) and with signes of hyperproliferative processes of reproductive system according to the data of ultrasound survey of uterus and the results of histology investigations of uterine mucosal scrapings were used for construction of model.Results of the study. On the basic of analysis of coefficients of logical model of regress the result was determined. Presence in women operation on the appendages of uterus promotes the risk of development of heavy degree of flow of disorders in menopause (p = 0.006) with odds ratio (OR) = 7.6 and the 95% confidence interval (CI) 1.8–32.8. Presence of chronic inflammatory diseases of privy parts (p = 0.004, OR = 27.6, 95% CІ 2.8–269.7), presence of hypermenstrual syndrome (p = 0.009, OR = 7.0, 95% CI 1.6–29.7), presence of diseases of liver and bilious ducts (p = 0.001, OR = 9.9, 95% CI 2.5–40.1), presence of stomach and intestine diseases (p = 0.010, OR = 5.9, 95% CI 1.5– 23.0) promotes the risk of development of heavy degree of flow of menopausal disorders.Conclusions. Presence for women with hyperproliferative processes of the reproductive system an operation on the appendages of uterus, chronic inflammatory diseases of genitals, hypermenstrual syndrome, diseases of liver and bilious ducts, stomach and intestine promotes the risk of development of heavy degree of flow of menopausal disorders.
Interferência da salinidade do mar na composição centesimal da macroalga Caulerpa cupressoides var. flabellata
Authors: Costa Mariana Santana Santos Pereira , Cordeiro Sara Lima , Almeida-Lima Jailma , Costa Leandro Silva , Rocha Hugo Alexandre Oliveira
Published: December 2017

Macroalgas marinhas são consumidas em grande quantidade em países asiáticos. Contudo, o seu consumo em países ocidentais, como o Brasil, ainda é muito baixo por várias razões. Uma delas é a falta de informações sobre a composição centesimal das macroalgas brasileiras. Este dado é importante para o uso de um alimento em várias atividades relacionadas com as áreas de nutrição humana e ciências dos alimentos. Neste trabalho, objetivou-se analisar a composição química, através do método de composição centesimal, da macroalga verde Caulerpa cupressoides var. flabellata, coletada em duas diferentes praias do litoral do Rio Grande do Norte (Camapum e Búzios). Os dados mostraram que a salinidade da água dessas duas praias é bem distinta: em Búzios é de 33,7 ppm; em Camapum, 40,5 ppm. Apesar disso, a composição centesimal da C. cupressoides não variou com a salinidade. Ainda, foi possível observar uma baixa quantidade de lipídios e uma alta quantidade de proteínas em C. cupressoides, nesse caso, maior até do que aquela encontrada em outras algas comestíveis. Os dados apontam que C. cupressoides poderia ser uma fonte alternativa de baixo custo de proteínas, tanto para uso em nutrição animal, como humana.
Fauna de Euglossina (Hymenoptera: Apidae) de um fragmento de Mata Atlântica do Alto Oeste Potiguar, Rio Grande do Norte
Authors: Guimarães-Brasil Michelle De Oliveira , Brasil Daniel De Freitas , Mahlmann Thiago , Souza Eduardo Alves de
Published: December 2017

As abelhas da subtribo Euglossina encontram-se amplamente distribuídas na região Neotropical, sendo mais diversificadas nas florestas úmidas. Objetivou-se realizar um levantamento das espécies desta subtribo em um fragmento de Mata Atlântica, um remanescente de brejo de altitude, localizado em uma região do Semiárido Brasileiro. O estudo foi conduzido no município de Portalegre, Rio Grande do Norte, entre os meses de fevereiro e agosto de 2015. A coleta de dados foi realizada mensalmente entre às 08h00 e 16h00, com a utilização de armadilhas contendo as essências eucaliptol, eugenol e vanilina. Foram coletados um total de 123 machos, distribuídos em quatro gêneros e seis espécies, sendo elas: Eufriesea danielis (43,09%), Euglossa melanotricha (25,20%), Euglossa cordata (15,45%), Eulaema nigrita (13,82%), Euglossa fimbriata (1,63%) e Exaerete dentata (0,81%). O intervalo entre 08h00 e 10h00 foi o de maior atividade, com 54,4% do total dos machos coletados. A comunidade de abelhas da região estudada apresentou maior preferência pelo eucaliptol, atraindo cinco espécies e 67 indivíduos (53,6%). A espécie Eufriesea danielis é reportada pela primeira vez para a região Nordeste do Brasil, enquanto que Exaerete dentata tem seu primeiro registro para o estado do Rio Grande do Norte.

Euglossina (Hymenoptera: Apidae) fauna of a fragment of the Atlantic Rainforest of the Alto Oeste Potiguar, Rio Grande do Norte, Brazil

Abstract: The bees of the Euglossina subtribe are widely distributed in the Neotropical region, being more diversified in the humid forests. The purpose of this research was to carry out a survey of the species of this subtribe in a fragment of Atlantic Forest, a remnant of altitude swamp, located in a region of the Brazilian Semiarid. The study was conducted in the municipality of Portalegre, Rio Grande do Norte, between February and August 2015. Data collection was performed monthly between 08h00 and 16h00, using traps containing the eucalyptol, eugenol and vanillin essences. A total of 123 males, distributed in four genera and six species were collected, which are: Eufriesea danielis (43.09%), Euglossa melanotricha (25.20%), Euglossa cordata (15.45%), Eulaema nigrita (13.82%), Euglossa fimbriata (1.63%) and Exaerete dentata (0.81%). The interval between 8:00 a.m. and 10:00 was the most active, with 54.4% of the total collected males. The community of the bees studied region showed greater preference for eucalyptol, attracting five species and 67 individuals (53.6%). The species Eufriesea danielis is reported here the first time for the Northeast region of Brazil, while Exaerete dentata has its first record for the state of Rio Grande do Norte.
Efeito das práticas de manejo de plantas daninhas sobre a produção do feijão-caupi
Authors: Oliveira Kelder José Alves de , Pessôa Uriel Calisto Moura , Souza Anielson dos Santos , Pimenta Thiago Alves , Muniz Rafael Vitor da Silveira , Araújo Neto Antônio Gomes de
Published: December 2017

O feijão-caupi destaca-se entre as lavouras anuais na região Nordeste pelo seu potencial produtivo e valor nutricional. Todavia, vem apresentando uma produtividade aquém do seu verdadeiro potencial produtivo, pela severa interferência da comunidade infestante, que podem acarretar em redução no rendimento de grãos em até 90%. Assim, objetivou-se avaliar o efeito de diferentes manejos de plantas daninhas, na cultura do feijão-caupi, identificando a partir dos componentes de produção da cultura, o mais eficiente. O trabalho foi realizado no Centro de Ciências e Tecnologia Agroalimentar da Universidade Federal de Campina Grande, Campus Pombal. O delineamento experimental foi o de blocos casualizados em esquema fatorial 4 x 2, sendo os fatores: duas cultivares (BRS Marataoã e BRS Rouxinol) e quatro manejos das plantas daninhas (mecânico, químico, físico e sem controle), com quatro repetições. Os componentes de produção, constaram de Massa (kg) das vagens, número de grãos por vagem, tamanho (cm) e diâmetro (mm) das vagens, Massa (kg) de mil sementes e produtividade (kg) total de grãos. Houve drástica redução na produtividade das plantas cultivadas no tratamento sem controle, independente do cultivar.
Trends of Breastfeeding in the United Arab Emirates (UAE)
Authors: Taha Zainab
Published: December 2017

In 1990, the World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) declared a “global goal” for protection, promotion and support of breastfeeding (Innocenti Declaration) (WHO/UNICEF 1990). In 1991 health care authorities in the UAE started to implement breastfeeding promotion and support programs across the country. To date, there are ongoing national efforts and investments in these programs including development and update of policies and strategies.This mini review evaluates the trends of infant and child feeding practices in the UAE over the last few decades to assess the progress attributed to the rollout and implementation of breastfeeding promotion programs.Keywords: Breastfeeding, United Arab Emirates, Nutrition.
TREND ANALYSIS OF RAINFALL, TEMPERATURE AND RUNOFF DATA: A CASE STUDY OF RANGOON WATERSHED IN NEPAL
Authors: Pal Amar Bahadur , Khare Deepak , Mishra Prabhash Kumar , Singh Lakhwinder
Published: December 2017

Purpose: The study has been carried out to investigate and assess the significance of the potential trend of three variables viz. rainfall, temperature and runoff over the Rangoon watershed in Dadeldhura district of Nepal.Methodology: In this study, trend analysis has been carried out on monthly, seasonal and annual basis using the data period between 1979 to 2010 for rainfall and temperature and 1967 to 1996 for runoff. Mann-Kendall test and Sen’s slope estimate test were applied to identify the existing trend direction and Sen’s slope estimator test were used to detect the trend direction and magnitude of change over time.Main findings: The most important findings are, i) There is warming trends over the Rangoon watershed as Mann-Kendall statistic (Z-value) for most of the maximum temperature values are positive, ii) Rainfall and runoff affected by fluctuations every year though the annual rainfall showing a rising trend whereas runoff showing a falling trend. The rainfall seasonal trend analysis indicates that monsoon and post-monsoon period showed a positive rainfall trend with z statistics of +1.93, and +1.12 respectively, whereas pre-monsoon and winter seasons showed a negative trend with z statistics of -1.02, and -0.54 respectively. However, the annual rainfall in the Rangoon watershed showed a positive trend with a z value of +1.70.Importance of this study: This case study has been undertaken to investigate the trends of important climatic variables viz. rainfall, temperature which have a direct impact on the agriculture of the region.Originality / Novelty of study: This is an original research work undertaken under the M. Tech programme during 2016-17 at IIT Roorkee by the scholar Er. Amar Bahadur Pal from Nepal.
MUSGOS COMO BIOINDICADORES DE METAIS PESADOS NO AMBIENTE
Authors: SOUZA Eliane Ferreira de , NOBREGA Michele Aparecida dos Santos , PONTES Montcharles Da Silva
Published: December 2017

Recentemente, inúmeras pesquisas envolvendo degradação ambiental oriunda das poluições atmosférica, terrestre e aquática, tem como foco o uso de animais ou vegetais, que apresentem respostas no sentido de controlar e indicar o nível de deterioração nos ambientes afetados por ações antrópicas. Dentre os organismos indicadores denominados biomonitores, estão os musgos do Filo Bryophyta responsáveis por respostas significativas frente aos impactos gerados pelo descarte indevido de substâncias, que contêm em sua composição metais pesados. Os metais pesados são considerados um dos principais poluentes que afetam os recursos naturais. Geralmente, os mesmos são oriundos de técnicas agrícolas ou mecanismos urbanos que produzem resíduos. Nesta linha, o presente estudo de revisão visa relacionar, principalmente, os efeitos da poluição dos recursos naturais a partir do uso de musgos como bioindicadores de traços metálicos no ambiente.
ANÁLISE DA ABORDAGEM E CONHECIMENTO DO TEMA PARASITOSES CAUSADAS POR PROTOZOÁRIOS EM ESCOLAS PÚBLICAS DO MUNICÍPIO DE SALINAS-MG
Authors: LIMA Nathália Bastos , SANTOS Larissa Mendes
Published: December 2017

As parasitoses são doenças que trazem prejuízos à população e estão presentes em muitas regiões, sendo as ocasionadas por protozoários bem comuns no Norte de Minas Gerais. Este trabalho visa analisar o grau de conhecimento sobre o tema “Parasitoses humanas causadas por protozoários”, nas turmas de terceiro ano do Ensino Médio em escolas públicas do município de Salinas-MG. Para isso foram aplicados questionários sobre as doenças causadas por protozoários, os sintomas, fases clínicas da doença, exemplos de protozoários e mecanismos de transmissão. Além disso, foi aplicado um questionário para os docentes que ministram a disciplina de Biologia para verificar a visão quanto ao ensino do conteúdo Parasitologia e como este é abordado em sala de aula, e por fim analisou-se o livro utilizado pelos docentes, caracterizando o conteúdo das parasitoses causadas por protozoários quanto à linguagem utilizada e atividades propostas. Os resultados indicam que os estudantes precisam adquirir um melhor aprendizado significativo sobre o tema, mostrando a necessidade de se enfatizar alguns pontos. Também foi observado que os docentes mostraram-se preocupados em abordar esse conteúdo apesar de não terem recursos suficientes para isso. O livro didático analisado aborda este conteúdo de forma superficial e não enfatiza pontos importantes como medidas de prevenção e formas de contágio. Com isso foi possível concluir que a educação para saúde deveria ser trabalhada de forma transversal para que os alunos sejam autores de suas próprias mudanças.
Percepciones, conocimientos y actitudes de profesionales de la salud latinoamericanos acerca de la salud bucodental de gestantes
Authors: Corchuelo-Ojeda Jairo , Romero-Velez Eduardo , Gutiérrez-Grajales Aura Cristina
Published: December 2017

Objetivo: identificar percepciones, actitudes y brechas de conocimientos acerca de la salud bucodental de gestantes entre ginecoobstetras y profesionales de salud latinoamericanos.Materiales y métodos: estudio de corte transversal en especialistas en obstetricia y ginecología, médicos residentes, médicos generales y enfermeras profesionales. Muestreo aleatorio simple con un marco muestral de 680 profesionales de salud. Se calculó un tamaño de muestra de 103 sujetos, con un nivel de confianza del 95 %, un valor de prevalencia de conocimientos del 65 % y una precisión del 10 %. Se aplicó un cuestionario autodiligenciado, especialmente diseñado a partir de estudios previos. Se midieron las características sociodemográficas, los conocimientos, las actitudes y las percepciones. Se aplicó estadística descriptiva.Resultados: se obtuvo un total de 84 encuestas de 103 profesionales seleccionados. Estas correspondieron a: ginecoobstetras (53,6 %), médicos generales (23,8 %), enfermeras profesionales (16,7 %) y estudiantes de posgrado de la especialización en ginecología y obstetricia (6 %). Se dispuso información de profesionales de 13 de los 19 países. El 57,1 % no había recibido capacitación en patologías orales. El 20 % de los encuestados tuvo un nivel alto de conocimientos, y el 25 % tuvo una actitud positiva.Conclusión: se presentan brechas entre los diferentes profesionales encuestados acerca de la salud bucodental de las gestantes. Se recomienda capacitación y trabajo en equipo.
Modelagem E Controle De Um Driver De Leds De Baixa Frequência Baseado No Pré-Regulador Boost
Authors: José Nogueira Fernando , Gomes Resende Lucas Henrique , Moreira Ferraz Ruan , De Oliveira Coelho Fabricio , Salvador da Silva Edmar , Márcio Soares Guilherme , Antônio Carvalho Braga Henrique
Published: December 2017

Este artigo detalha a análise e o projeto de um controlador (ou driver) de LEDs baseado no pré-regulador boost de baixa frequência e sua aplicação em luminárias de iluminação pública. A análise do circuito é revisada, sendo proposto um modelo dinâmico do conversor e metodologias de projeto para o controlador e compensador de malha fechada. Resultados experimentais são mostrados para uma luminária LED de 165 W. Em complementação ao texto, é realizada uma discussão sobre o fenômeno da cintilação (flicker) ocasionado pela corrente de baixa frequência fornecida aos LEDs por esse driver.
A Front-End Bridgeless Power Factor Corrector For Electric Vehicle Battery Chargers
Authors: Carlos Fischer Jefferson , Andressa da Silva Juliana , Rômulo de Novaes Yales , Vidal Garcia Oliveira Sérgio
Published: December 2017

In this paper, a bridgeless power factor corrector converter is suggested for electric vehicle battery chargers. The converter is applicable as a front-end stage for residential charging, i.e. automotive level 1. It is presented a steady state operation analysis for the proposed converter. It operates in current continuous conduction mode controlled by a voltage outer loop and a current inner loop control strategy. Experimental results were performed for a 1 kW prototype, considering 220 V grid voltage, 400 V dc output voltage, 70 kHz switching frequency, and the control system implemented by the UCC28070. The experimental results are satisfactory, which demonstrate a peak efficiency of 98.4% at half load, and features high efficiency from light load to full load. Additionally, the input current THD is less than 5% from half to full load and the power factor is higher than 0.99 from half to full load.
Molecular genetic studies on Nellore and Deccani sheep using microsatellite markers
Authors: Amareswari P. , Gnana Prakash M. , Ekambaram B. , Mahendar M. , Krishna Ch Hari
Published: December 2017

The study was undertaken to understand the genetic architecture of Deccani and Nellore sheep breeds and to assess the genetic distance between the breeds. Allele diversity, genetic variability and population structure in the two breeds were estimated using 30 microsatellite markers. A total of 100 sheep, 50 each from Deccani and Nellore breeds were genotyped. The total number of alleles observed was 254 and 260 in Deccani and Nellore, respectively. The mean expected heterozygosity among the breeds ranged from 0.79 (Deccani) to 0.80 (Nellore) whereas the mean observed heterozygosity levels ranged from 0.77 in Deccani to 0.78 in Nellore sheep. The overall mean inbreeding coefficient was 0.029 in Deccani and 0.031 in Nellore sheep and of the 30 loci studied, 14 loci in Deccani and 16 loci in Nellore sheep showed negative inbreeding coefficient indicating the presence of outbreeding. However, eight loci (BM1314, BM6506, BM8125, ILSTS28, MAF70, MCM140, OarCB226 and OarFCB128) showed positive, mild to moderate inbreeding ranging from 0.007 to 0.25 in Deccani and 0.066 to 0.37 in Nellore sheep studied. The FIS values ranged from -0.372 to 0.74, FST values ranged from 0.001 to 0.172 and FIT values ranged from -0.370 to 0.728 between the Deccani and Nellore sheep breeds studied. The PIC values ranged from 0.498 to 0.886 with a mean of 0.773 in Deccani and from 0.574 to 0.894 with a mean of 0.777 in Nellore breed. The information generated from the present study will be valuable for setting conservation priority of these two breeds.