bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular detection and genetic variability of Ehrlichia canis in pet dogs in Xinjiang, China
Authors: Mengfan Qiao , Lixia Wang , Ying Lei , Yan Ren , Kuojun Cai , Jinsheng Zhang , Zaichao Zhang , Weiwei Yu , Yelong Peng , Xuepeng Cai , Chongyang Li , Jun Qiao , Qingling Meng
Published: May 2020

Background and Aim: As a tick-borne zoonotic pathogen, Ehrlichia canis has already posed a threat to public health and safety. This study aimed to clarify the prevalence and molecular characteristics of E. canis in pet dogs in Xinjiang, China.

Materials and Methods: A total of 297 blood samples of pet dogs and 709 skin ticks (Rhipicephalus sanguineus sensu lato) were subjected to molecular detection using PCR for E. canis 16S rRNA gene, and then, positive samples were amplified, sequenced, and phylogenetically analyzed for E. canis gp36 gene.

Results: The PCR detection showed that the positive rate of PCR was 12.12% (36/297) in blood samples and 15.23% (108/709) in tick samples, respectively. Based on the phylogenetic analysis of E. canis gp36 protein, these E. canis strains in different geographical regions of the world can be divided into Genogroup I and Genogroup II. Among them, the Xinjiang epidemic strain XJ-6 and 533, 36, 1055, Kasur1, and Jake strains were clustered into subgroup 1.1 of Genogroup I, while the XJ-2, XJ-21, and XJ-35 strains and the TWN1, TWN4, CM180, and CM196 strains were closely related and belonged to subgroup 2.2 of Genogroup II, displaying high genetic diversity.

Conclusion: This is the first study focusing on the molecular epidemiology of E. canis infection in pet dogs, which revealed that E. canis infection had been occurred in Xinjiang, China. More importantly, this study confirmed that the substantial variability in immunoreactive protein gp36 from E. canis strains circulating in pet dogs.
Szövegértésre és szövegfeldolgozásra épülő képességfejlesztés megvalósítása online tanulási környezetben
Authors: Habók Anita , Magyar Andrea
Published: May 2020

A felső tagozatos általános iskolások olvasási szokásait a papíralappal szemben egyre inkább meghatározza az online környezet. Felső tagozattól kezdve megnövekszik a tantárgyak száma, ezzel együtt a tantárgyakhoz kapcsolódó szövegek mennyisége is emelkedik az alsó tagozathoz képest. Míg a szövegek egy részével papíralapon találkoznak a tanulók, a másik részét digitális formában olvassák. Ez az újfajta tanulási környezet szükségessé teszi, hogy a tanulók olvasási stratégiáikat az online helyzetekben is gyakorolják, valamint új stratégiákat sajátítsanak el. A tanulmányunkban bemutatott fejlesztő program felső tagozatos tanulóknak tanít szövegértéshez és szövegfeldolgozáshoz kapcsolódó tanulási stratégiákat, továbbá lehetővé teszi a stratégiák gyakorlását. A fejlesztő program tantárgyfüggetlen tartalomra épülve valósítja meg a tanulást. Az eredmények azt mutatták, hogy a program osztálytermi környezetben alkalmazható, továbbá egyéni tanulás keretében is megoldhatóak a feladatok. A tanulók eredményei arra hívták fel a figyelmünket, hogy az együttműködés okozott legnagyobb nehézséget a feladatok megoldása során. Az eredmény azt jelzi, hogy ilyen típusú feladatok intenzívebb gyakorlására lenne szükség. A tanároktól kapott visszajelzések segítik a program jövőbeli továbbfejlesztését. Arra mutattak rá az észrevételek, hogy a tanulók számára az eddigieknél részletesebb, differenciáltabb magyarázatokra és segítségnyújtásra van szükség. A különféle tanulási stílusok alapján pedig a szemléltetés mellett a feladatok felolvasása és szóbeli magyarázata is támogatóbb környezetet teremtene. Mivel programunk tanulóbarát környezet kialakítását tűzte ki célul, mely a tanulók számára egyben motivációt is jelent, ezért a tanulói eredmények részletesebb dokumentálását is tervezzük megvalósítani.
Experimental investigation of new optical antenna designs found by a genetic algorithm
Authors: Feichtner Thorsten , Selig Oleg , Kiunke Markus , Hecht Bert
Published: May 2020

Most currently studied optical antenna geometries are based on radio wave antenna designs. However, material properties at optical frequency largely differ from the perfect metal case at radio frequencies. Recently, evolutionary algorithms (EA) [1] were used in the field of Plasmonics to find novel geometries however with strongly limited configuration space [2].

We developed an EA capable of handling complex multiparticle geometries. In a first application we optimized near-field intensity enhancement produced by antenna structures in a single point [3]. We found a novel geometry, i.e. a nano antenna/split-ring hybrid antenna for which the near-field intensity enhancement is strongly increased. Yet these structures are not suitable for experimental realization.

Here we show the results of an adapted EA which uses primitive elements that are compatible with an experimental fabrication step using FIB. The performance of the realized structures is characterized by means of confocal two-photon-photoluminescence-(2PPL)-microscopy. We find that the hierarchy of performances found in individuals taken from sequential generations of the EA can be reproduced in fabricated structures.
Determinants of demand for banking facilities a practical study of a sample of beneficiaries in DHI QAR governorate
Authors: Chetheer Mazaal Wafaa
Published: May 2020

Banking facilities are a very important function, as banking departments are concerned about the most important aspects of the recruitment of their funds and the main source of their revenues, The banks have been and continue to act as a financial intermediary between the audience of depositors and investors, they collect savings and guide them to different areas of investment, So we find it interested in the development of credit policies that take into account the achievement of the objectives of the bank and satisfy the requirements of customers and banking laws and legislation, From here, the research highlighted the most important factors affecting the demand for these facilities by applying to a sample of beneficiaries in Dhi Qar Governorate through the distribution of a questionnaire form designed for that purpose, The results of the study showed that the most important of these factors is the high interest rates and discount, which is an obstacle in the request for banking facilities, In light of these recommendations, the most important of which was the need to reconsider the interest rates and discount to encourage customers to request banking facilities and commensurate with the prevailing economic situation and investment opportunities available.Â Â
DAYA TARIK MENJAMURNYA RESTORAN KOREA DI YOGYAKARTA
Authors: Hasanah Ummul - , Rencidiptya Theresia Avila
Published: May 2020

Korean restaurants in Yogyakarta are flourishing in the past ten years.  A lot of Korean restaurants, either in small or big scale, are not only attracting people living in Yogyakarta but also attracting the tourists coming to Yogyakarta. This paper is the result of quantitative and qualitative research with the research object students of Diploma Korean Language Program, Vocational College, Gadjah Mada University. The respondents were selested because those students are millenial generation who follow the fast growing of Korean restaurants in Yogyakarta while at the same time the main customers of those restaurants. As result of the research, the reasons why Korean restaurats exist in Yogyakarta because they need to expand their market outside of Korea and many people are interested coming to Korean restaurants because it is the easiest way to taste Korean cuisine as part of Korean culture without coming to South Korea. Moreover, the difficulties experienced by customers when eating in Korean restaurants are questioning whether the food or drink served is halal (because pork and alcohol are the common dishes in Korea) and the price which is more expensive than the price of Indonesian local foods .Tulisan ini membahas mengenai fenomena menjamurnya berbagai restoran Korea di Yogyakarta dalam kurun waktu sepuluh tahun terakhir.  Berbagai restoran Korea, baik dalam skala kecil maupun besar tersebut tidak hanya menarik bagi warga yang tinggal di Yogyakarta tetapi juga turis yang datang ke Yogyakarta. Tulisan ini merupakan hasil penelitian kuantitatif dan kualitatif dengan objek penelitian mahasiswa Prodi D3 Bahasa Korea, Sekolah Vokasi, Universitas Gadjah Mada. Objek tersebut dipilih karena mereka merupakan generasi millenial yang mengikuti perkembangan pesat tumbuhnya restoran Korea di Yogyakarta sekaligus penikmat utama dari restoran-restoran tersebut. Tulisan ini juga membahas mengapa restoran Korea tersebut banyak muncul di Yogyakarta dan mengapa banyak orang tertarik untuk pergi ke restoran Korea di Yogyakarta. Selain itu juga dibahas mengenai hambatan saat berkunjung ke restoran Korea, diantaranya adalah makanan yang disajikan belum tentu halal (karena daging babi dan alkohol adalah menu yang sangat wajar di makanan Korea) dan harga yang lebih mahal dari makanan Indonesia.
A RAINBOW ON THE TABLE: Historical Study Of Culinary Diversity In Solo
Authors: Priyatmoko Heri
Published: May 2020

This research attempts to understand the history of culinary diversity in Solo as a symbol of cultural harmony, as well as a regional economic power. The purpose of this research is motivated by the fact that Solo is known as a “radical city” and a city of conflict at national level. This study is expected to give a more comprehensive understanding of portrait of ethnic harmony which is reflected in the culinary cultures in order to lessenthe negative image of Solo. The method used is historical method, including heuristics (gathering of sources), source criticism, analysis/interpretation and writing. The researcher dedicated most time and energy to do library and document research and conduct some interview with the culinary businessmen. The researcher applies the acculturation theory in order to understand the process of culinary diversity occurrence. The result shows that the diversity of culinary of Solo is created as a result of intensive inter-cultural association and is supported by the creativity of local communities in addressing a challenge that led to the creation of new types of food. The existence of Javanese, European, Chinese, and Arabic communities in the past is accounted for the diversity of food on the table, which becomes a symbol of social harmony. From tourism perspective, the character of the people who have hobby of eating out and the availability of various types of culinary strengthen the image of Solo City as “keplek ilat” (mouthwatering) city. This fact in turn becomes the economic power of Solo City.
Plastics that made history - the contribution of conservation science for the history of the Portuguese Plastics Industry
Authors: de Sá Susana França , da Cruz Sara Marques , Callapez Maria Elvira , Carvalho Vânia
Published: May 2020

The plastic objects from our cultural heritage are material testimonies of our history, technology and industry. Still, in Portugal, there is no museum of plastics, and the collections are spread through private collectors and industries. The research project, 'The Triumph of Bakelite - Contributions to a History of Plastics in Portugal', aims at creating this museum. To this end, the research work gave rise to the exhibition, 'Plasticity - A History of Plastics in Portugal', in Museu de Leiria in 2019. This study focuses on the contribution of conservation science for the writing of this history and preparation of ca. 150 historical plastic objects for display. Bakelite, melamine, polyethylene, polypropylene, polystyrene and plasticized polyvinyl chloride are just a few examples of the polymers identified by infrared spectroscopy. This identification was crucial to tell the history of the plastics industry in Portugal. Both the spectra and characteristic absorption bands of each polymer are presented.
Clothing problems and expectations of pregnant women
Authors: Arga Şahinoğlu Meyrem , Buluş Hande Ecem
Published: May 2020

Pregnancy period is an important and special process due to the physiological, psychological, social changes that occur before and after birth and the change in body appearance.  In this process, it is very important for pregnant women to look beautiful in clothes and feel comfortable. Accordingly, it is aimed to determine the preferences, problems and expectations of pregnant women regarding pregnant clothes.

Pregnant women living in Ankara province are the population of the research using screening method; the sample consists of 247 pregnant women selected by the purposive sampling method.  A questionnaire was prepared to collect data in the research. The data obtained as a result of the survey were analyzed using statistical methods and interpreted over tables. As a result of the research; pregnant women are expensive when purchasing maternity clothes and are not suitable for the body; while using maternity clothes, it is concluded that the colors of the fabrics fade and whether the clothes can be worn comfortably or not.

​Extended English summary is in the end of Full Text PDF (TURKISH) file.

Özet

Hamilelik dönemi, doğum öncesinde ve sonrasında yaşanan fizyolojik, psikolojik, sosyal değişimler ve vücut görüntüsünde yaşanan değişiklik nedeniyle önemli ve özel bir süreçtir. Hamile kadınların bu süreçte giysilerin içinde güzel görünmek ve kendilerini rahat hissetmeleri oldukça önemli olmaktadır. Bu doğrultuda hamile kadınların hamile giysilerine ilişkin tercihleri, sorunları ve beklentilerinin belirlenmesi amaçlanmaktadır.

Tarama yönteminin kullanıldığı araştırmanın evrenini, Ankara ilinde yaşayan hamile kadınlar; örneklemini ise amaçlı örnekleme yöntemi ile seçilen 247 hamile kadın oluşturmaktadır. Araştırmada veri toplamak amacıyla anket hazırlanmıştır. Anket sonucunda elde edilen veriler istatistiksel yöntemlerden faydalanılarak analiz edilmiş ve tablolar üzerinden yorumlanmıştır. Araştırma sonucunda; hamile kadınların, hamile giysisi satın alırken pahalı olması ve vücuda uygun giysi olmaması; hamile giysisi kullanırken ise, kumaşların renklerinin solması ve giysilerin rahat giyilip çıkarılmaması konularında sorun yaşadıkları sonucuna ulaşılmıştır.
Melanoma Incidence in Czech Republic, the Relation between Histology, Body Site of Melanoma, and Duration of Lesions
Authors: Čelakovská Jarmila , Bukač Josef , Čáková Lenka , Šimková Marie , Jandová Eva
Published: May 2020

Aim: To evaluate the occurrence of melanoma in the period 1996–2017 in East Bohemia region in the Czech Republic. Method: We studied the incidence of melanoma and the age of diagnosis (adjusted calculation) and the parameters such as histology, body site of lesions, the length of the duration of lesions in 2810 patients. Results and conclusion: No change in the occurrence of melanoma and in age of melanoma during this period was found. The difference between men and women was not confirmed in histology, but the difference between men and women was confirmed in the body site of lesion and in the length of duration of lesion. No relation between the length of duration of lesions from which melanoma had originated and its histology was confirmed. The relation was confirmed between histology and body site of melanoma. The relation between the body site and the length of duration of previous lesions was confirmed also. The increasing occurrence of melanoma on the trunk according to the duration of the previous lesions was confirmed.
Long-term intervention of taurocholic acid over-expressing in cholestatic liver disease inhibits the growth of hepatoma cells
Authors: Zhang Xiujuan , Nan De , Zha Chunting , He Gaohong , Zhang Wenjun , Duan Zhijun
Published: May 2020

Bile acids usually build up in patients with cholestatic liver disease. It was found that the concentration of taurocholic acid (TCA), one of the taurine conjugates of primary bile acids in serum, was elevated the most. While the role played by TCA in the disease is unclear, there is concern whether TCA contributes to the development of hepatocarcinoma from cholestasis. In the present study, the cell viability, flow cytometry, real-time polymerase chain reaction, intracellular ROS measurement, and intracellular Ca2+ measurement were used to investigate the effects of TCA on THLE-2 and HepG2 cells. The results showed that TCA is capable of inhibiting HepG2 cell growth whereas it has relatively little or no impact on that of THLE-2 cells until later stages of 16-day treatment. The growth inhibition is a result of cell apoptosis induced by the increase of Ca2+ and ROS level, and also associated with the increased expression of c-Myc, CEBPÎ±, TNF-Î±, ICAM-1, VCAM-1, CXCL-2, Egr-1. HepG2 growth inhibition could contribute to the research on the treatment methods of patients already with hepatocarcinoma.
Effect of astragaloside IV on cognitive dysfunction in rats with cerebrally infarcted via TGF-Î² / Smad signaling pathway
Authors: Li Li , Guo Yanling , Zhao Yan'an , Wei Jiahong , Jin Yuanyuan
Published: May 2020

Cerebral infarction is an acute cerebrovascular disease caused by abnormal blood circulation in the brain. In the present study, we investigate the effect of astragaloside IV on cognitive dysfunction in cerebrally infarcted rats via transforming growth factor-Î² (TGF-Î²) / Smad signaling pathway. For this purpose, 45 rats were divided into three groups including astragaloside, model, and control. 30 of 45 healthy adult male SD rats were randomly selected to establish an acute cerebral infarction model. 15 modeled rats were enrolled as a model and astragaloside group, and another 15 rats as a blank control group. The rats in the astragaloside group were fed with astragaloside IV according to 1.08 g/kg body weight, and those in the blank group and model group were given matching normal saline. The levels of TGF-Î², Smad1, Smad3 and Smad7 of TGF-Î²/Smad signaling transduction pathway at T0 (week 0), T1 (week 3) and T2 (week 6) were determined by enzyme-linked immunosorbent assay (ELISA). The modified neurological severity score (mNSS) was used to evaluate the improvement of cognitive dysfunction in rats. The mNSS of rats with cerebral infarction in the astragaloside group was lower than that in the control group and model group (P< 0.05). While the levels of TGF-Î², Smad1, Smad3 and Smad7 in the astragaloside group were higher than those in the control group and model group (P< 0.05). Astragaloside IV plays an important role in improving cognitive dysfunction in rats with cerebral infarction while affecting the levels of TGF-Î², Smad1, Smad3 and Smad7 and activating TGF-Î² / Smad signaling pathway.
Effects of dexmedetomidine pretreatment on rats with sepsis-induced acute kidney injury and miR-146a expression
Authors: Ni Jinping , He Jiang , Kang Li , Zhong Zhidong , Wang Liren , Yin Shuzhou
Published: May 2020

The current research aimed to study the effects of dexmedetomidine (DEX) pretreatment on rats with sepsis-induced acute kidney injury (SAKI) and miR-146a expression. The model of SAKI was established through the tail vein injection of lipopolysaccharide (LSP). We used an automatic biochemical analyzer to detect serum urea nitrogen (BUN) and creatinine (Cre) levels. The expression levels of urine KIM-1 and NGAL and serum IL-1Î² and IL-6 were analyzed by enzyme-linked immunosorbent assay (ELISA). The content and activity of superoxide dismutase (SOD) were detected by the xanthine oxidase method. The content of malondialdehyde (MDA) was determined by the thiobarbituric acid (TBA) method. Reactive oxygen species (ROS) was detected by fluorescent probe DCFH-DA. Catalase (CAT) was detected by potassium permanganate titration. The expression level of miR-146a in the renal tissue and serum was detected by RT-PCR. The expression levels of Nrf2 and HO-1 proteins were detected by Western blot. Compared with those in the model group, rats in the DEX group had significantly lower expression levels of serum BUN, Cre, IL-1Î², and IL-6, and oxidant markers MDA and ROS, but significantly higher expression levels of miR-146a and antioxidant markers SOD and CAT. DEX pretreatment could improve the kidney morphology, injury severity, and Nrf2 and HO-1 proteins of rats with SAKI. In conclusion, DEX can improve oxidative stress and inflammatory responses in rats with SAKI, reduce the severity of the renal injury, and up-regulate the expression level of miR-146a.
Expression of MACC1 protein in gastric cancer and its effect on proliferation and invasion of gastric cancer cells
Authors: Zheng Gang , You Changjiang , Qiu Zhidong , Zheng Xiannian
Published: May 2020

To detect the expression of metastasis-associated colon cancer gene 1 (MACC1) protein in gastric cancer tissues, and analyze its relationship with clinicopathological parameters of gastric cancer and its effect on proliferation and invasion of gastric cancer cells. Methods: 71 patients with gastric cancer in Fifth Hospital in Wuhan from June 2014 to March 2018 were selected as research subjects. Western blot was used to detect the expression of MACC1 in gastric cancer tissue and normal gastric mucosa tissue, and gastric cancer cell SGC7901 was transfected. Transfection group (transfected with MACC1-siRNA), negative control group (transfected with siRNA-NC) and blank control group (untreated cells) were set up. After transfection, the expressions of MACC1 protein and mRNA in the 3 groups were detected by Western blot and qRT-PCR methods, the cell proliferation was detected by MTT method, and the invasion ability of cells in vitro was detected by Transwell chamber. Results: The expression of MACC1 protein in gastric cancer tissue was higher than the control group (P< 0.05). The expression of MACC1 protein in gastric cancer was related to the differentiation degree, infiltration depth, lymph node metastasis and different stages of gastric cancer (P< 0.05). After transfection, the expressions of MACC1 protein and mRNA in the transfection group was significantly lower than the negative control group and blank group (P< 0.05). There was no significant difference in cell viability between the blank group and negative control group at each time point (P> 0.05). Conclusion: MACC1 was highly expressed in gastric cancer tissues. The expression of MACC1 was related to the differentiation degree, infiltration depth, lymph node metastasis and staging of gastric cancer. Down-regulation of MACC1 could inhibit the proliferation and invasion of gastric cancer cells. This study provided a certain biological basis for early clinical prediction, diagnosis and treatment of gastric cancer.
Cell-free DNA as a biomarker for colorectal cancer: a retrospective analysis in patients before and after surgery
Authors: Zhong Yubing , Zhou Qing , Zhang Yun , Zhou Sujun , Zhang Guoqiang , Jiang Chao , Zhang Zheng , Zhang Xifen , Xu Juan , Jin Chen , Cao Lifen , Chen Lingxiang
Published: May 2020

This study was aimed at investigating the potential of cell-free DNA (cfDNA) as a biomarker for colorectal cancer prognosis. Sixty patients with colorectal cancer who had not undergone surgery were enrolled as study group. Their peripheral blood samples were collected, and peripheral blood of 30 healthy volunteers (control) was collected. The cfDNA concentration and integrity were determined using q-PCR so as to ascertain if cfDNA was associated with clinical presentations of the disease. Then, the specificities and sensitivities of cfDNA, CFA and CA199 were determined with ROC curve. The level and integrity of cfDNA in patients with colorectal cancer before surgery were significantly higher than those in patients with colorectal cancer after surgery, and cfDNA concentration of colorectal cancer patients after surgery was also significantly higher than that in healthy control group. However, the integrity was not significantly different from that of control group. There was a significant correlation between cfDNA concentration and TNM stage, differentiation degree and CEA expression, while cfDNA integrity was significantly correlated with TNM stage and degree of differentiation. Moreover, specificity and sensitivity of cfDNA concentration and integrity were higher than those of CEA and CA199. The TNM stage and cfDNA concentration were independent risk factors for progression-free survival (PFS) in colorectal cancer patients. In conclusion, cfDNA concentration and integrity were more sensitive and specific than traditional tumor markers (CA199, CEA). Thus, changes in cfDNA changes can be effectively used to determine the prognosis of postoperative colorectal cancer patients.
Atypical extraventricular neurocytoma: A case report
Authors: Zhang Peng , Wu Cui-Ying , Qin Jia-Zhen , Xu Ru-Xiang , Bai Miao-Chun , Wang Lu-Ping , Dai Yi-Wu , Li Xue-Zhen
Published: May 2020

Atypical extraventricular neurocytoma (EVN) is a rare condition characterized by diffuse tumor cell hyperplasia, increased neovascularization, increased necrosis, and aggressive characteristics. A case of a 25-year old man who presented with atypical EVN in his left parietal - occipital flaps is reported. Magnetic resonance imaging (MRI) revealed a well-defined globular mass with heterogeneous signals in the left parietal lobe, and mild perilesional edema. After left parietal craniotomy and tumor excision, pathologic examination of the resected tissue revealed that the lesion was localized mainly in the white matter and imbued with tumor cells possessing round hyperchromatic nuclei with perinuclear halos and increased microvascular proliferation. The patient underwent radiotherapy at 21st postoperative day. Over the past 26 months, the patient has been regularly followed up, and so far no neurologic deficits have been observed. The latest MRI showed that the tumor bed was stable with slight peritumoral edema. The results of clinical, histopathological and immunohistochemical examinations indicate that atypical EVN is a rare neoplasm with unique radiographic and pathologic characteristics. It possesses more aggressive properties than typical EVN.
Efficacy of cefotaxime combined with gamma globulins on C-reactive protein and procalcitonin in neonatal sepsis
Authors: Zhang Fan
Published: May 2020

C-reactive protein (CRP) is encoded by CRP or PTX1 gene and procalcitonin (PCT) is produced by the CALC-1 gene induction. Both PCT and CRP are known as valued biomarkers markers in prediction of Serious Bacterial Infections (SBI) in children. This experiment carried out to analyze the efficacy of cefotaxime combined with gamma globulins on neonatal sepsis and the effect on CRP and PCT. For this purpose, a total of 120 sepsis children were selected and randomly divided into observation and control groups. Children in the control group were treated with cefotaxime, while children in the observation group were treated with cefotaxime combined with gamma globulins. The two groups were compared in terms of the relative measures of efficacy, the total effective rate of treatment, the incidence of complications and serum CRP and PCT levels before and after treatment. The clinical measures of the observation group were all lower than those of the control group, and the total effective rate of the treatment was higher than that of the control group, while the incidence of complications was lower than that of the control group. In addition, before treatment, there was no difference in CRP and PCT between the two groups; after treatment, the above measures in the observation group were lower than those in the control group. It is concluded that Cefotaxime combined with gamma globulins in the treatment of neonatal sepsis has significant efficacy and is clinically more effective than cefotaxime monotherapy. This combination can shorten clinical symptom remission time and hospital stay, improve serum CRP and PCT levels and promote the recovery of children, worthy of promotion.
Effect of trimetazidine combined with perindopril on NT-proBNP level in rats with dilated cardiomyopathy
Authors: Lin Jinhai , Zhong Bin , Yan Jinling , Chen Lili
Published: May 2020

This experiment aimed to study the effect of trimetazidine combined with perindopril on NT-proBNP levels in rats with dilated cardiomyopathy (DCM). 40 SD rats were selected and 10 rats were randomly selected to continue to be fed as the blank group. The other 30 rats were injected with adriamycin to establish the DCM rat model. Then they were divided into 3 groups, namely control group (without any drug intervention), trimetazidine group (with trimetazidine single-agent intervention) and combination drug group (with trimetazidine combined with perindopril intervention), with 10 DCM rats in each group. After 4 weeks of intervention, left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD) and left ventricular end-systolic diameter (LVESD) of rats were measured by echocardiography. The changes of plasma brain natriuretic peptide (BNP) level and n-terminal pro-brain natriuretic peptide (NT-proBNP) were detected by ELISA. RT-PCR was used to detect the regulation of angiotensin II type 1 receptor (AT1Rs) and lamin A mRNA expression in rat myocardium. After the intervention, the LVEF%, LVEDD and LVESD measured values of the rats in the combination drug group were significantly better than those in the trimetazidine group and the control group (P< 0.05). The BNP, NT-proBNP and AT1Rs levels of the rats in the combination drug group were significantly lower than those in the trimetazidine group and the control group. The difference was statistically significant (p< 0.05). The lamin A expression of the rats in the combination drug group was significantly higher than that in the trimetazidine group and the control group. The difference was statistically significant (P< 0.05). Compared with trimetazidine single-agent, trimetazidine combined with perindopril can significantly improve the cardiac function of rats with dilated cardiomyopathy, reduce the serum NT-proBNP level and improve the expression of AT1Rs and lamin A in rats.
Effect of calcitriol combined with sevelamer carbonate on serum parathyroid hormone in patients with chronic renal failure
Authors: Zheng Hui , Liu Zhinan
Published: May 2020

This study aimed to observe and analyze the effect of calcitriol combined with sevelamer carbonate on serum parathyroid hormone in patients with chronic renal failure. This study included 180 patients who had been treated for chronic renal failure in our hospital were enrolled as research objects. The patients were randomly divided into two groups: a research group and a control group, each containing 90 cases. The research group was treated with calcitriol combined with sevelamer carbonate, and the control group was treated with calcitriol alone. The therapeutic effects of the two groups were observed and analyzed by SPSS 21. Comparing the levels of blood indexes (Ca, Cr, P, ALP, iPTH, TC, TG, LDL-C, HDL-C) of the two groups showed no significant difference between the two groups, P <0.05. Our results have the effect of different treatment regimens, the improvement effect of various blood indicators in the research group was significantly better than the control group, p<0.05.  We concluded that the combined therapy of calcitriol and sevelamer carbonate in chronic renal failure patients can significantly improve the therapeutic effect, and at the same time actively improve the serum parathyroid hormone level, which is a treatment model that can be popularized and applied.
The role of informal digital learning of English and a high-stakes English test on perceptions of English as an international language
Authors: Lee Ju Seong
Published: May 2020

This study investigated the relationship among informal digital learning of English (IDLE) practice, a high-stakes English test, English productive skills, and perceptions of English as an international language (EIL). Eighty-nine English as a foreign language (EFL) undergraduate students across three South Korean cities participated in the study. The participants submitted their scores in the Test of English for International Communication (TOEIC, South Korea’s most popular high-stakes English test), took English speaking and productive vocabulary-level tests, and completed surveys that measured the frequency of their IDLE activities and EIL perceptions. Results of the hierarchical multiple regression analyses showed that IDLE practice and TOEIC scores were significant predictors of EIL perceptions. The structural equation modelling analysis further revealed that IDLE practice partially mediated the relationship between TOEIC scores and EIL perceptions. This indicates that students with higher TOEIC scores tended to practise IDLE activities more frequently, which enabled them to experience diverse accents and users of English and, in turn, help increase their EIL perceptions. It also suggests that more proficient EFL speakers may not necessarily become competent EIL users. These findings are discussed with consideration of South Korea’s socio-educational contexts, followed by pedagogical implications for English language educators and test developers.
Dyskusja nad tezą o wzroście narcyzmu we współczesnych społeczeństwach
Authors: Barbara Gawda Barbara Gawda
Published: May 2020

The article aims to discuss the thesis on ‘narcissistic epidemic’ that was highlighted in publications from culture and social studies. The different ways of defining of narcissism, different concepts of narcissism, psychological characteristic of people displaying narcissism, and research focused on its description will be analyzed. To illustrate the famous thesis on ‘narcissistic epidemic’ in the modern world the data on the prevalence of narcissistic personality disorder in many countries, including Poland, will be discussed. The documented not too high prevalence of narcissistic personality disorder in high-income countries from the world seems to be stable. It means that the thesis on increasing level of narcissism in capitalist countries was not supported by the research from psychopathology.
Między Chinami a Zachodem. Etos pracy jako przejaw nowej odsłony „zderzenia cywilizacji”?
Authors: Banach Wiesław
Published: May 2020

Wiesław Banach, Między Chinami a Zachodem. Etos pracy jako przejaw nowej odsłony „zderzenia cywilizacji”? [Between China and the West. The ethos of work as a manifestation of new version of the „clash of civilizations”] edited by W. Banach, M.A. Michalski, J. Sójka, „Człowiek i Społeczeństwo” vol. XLVI: Między Chinami a Zachodem. Pytanie o źródła chińskiego sukcesu gospodarczego [Between China and the West. An inquiry into the sources of the Chinese economic miracle], Poznań 2018, pp. 121–143, Adam Mickiewicz University. Faculty of Social Sciences Press. ISSN 0239-3271.The purpose of this article is to compare the Chinese and Western value systems in terms of their suitability for economic development. The author focuses on a very important element of every economic culture which is the work ethos. He understands it as a conviction that only hard and systematic work gives the individual the chance to live in relative prosperity. The ethos of work understood in this way is one of the most basic and common cultural habits. It does not arise spontaneously, that is, in a natural way, but it must be developed and cherished, or cultivated. A comparison of the contemporary Eastern and Western work ethos can be helpful in understanding the causes of China’s economic success and the declining importance of the West. These considerations are carried out in the context of Samuel Huntington’s 25-year-old thesis about the growing importance of cultural factors in the modern world. According to the author of „Clash of civilizations”, such cultural factors as religion, tradition, customs, morality and everything called the system of values are now the source of a deepening global conflict and at the same time increasing economic distance between China and the West.
Czego warto się uczyć w zakresie zarządzania od Dalekiego Wschodu?
Authors: Karczewski Leszek
Published: May 2020

Leszek Karczewski, Czego warto się uczyć w zakresie zarządzania od Dalekiego Wschodu? [What is worth to learn in management from the Far East?] edited by W. Banach, M.A. Michalski, J. Sójka, „Człowiek i Społeczeństwo” vol. XLVI: Między Chinami a Zachodem. Pytanie o źródłachińskiego sukcesu gospodarczego [Between China and the West. An inquiry into the sources of the Chinese economic miracle], Poznań 2018, pp. 159–174, Adam Mickiewicz University. Faculty of Social Sciences Press. ISSN 0239-3271.The article emphasizes the need of learning from one’s own history mistakes and the success of other countries such as Japan and China. The author presented the current situation of Poland in both skeptical and optimistic perspectives. The transformation of 1989 is indicated as the genesis of current challenges of the country. In the next part of the article there are suggested actions that could be taken after the transformation in the field of state and organization management in order to realize the idea of Poland as the “second Japan”. The last part of the article is devoted to describing what can still be learned from the Far East countries in the field of economy and management.
Prevalence of dyslipidemia in Tibetan monks from Gansu Province, Northwest China
Authors: Fang Yan , Li Xing-hui , Qiao Yan , Wang Nan , Xie Ping , Zhou Gang , Su Peng , Ma Hui-yuan , Song Ji-yang
Published: May 2020

Tibetan monks have a special way of life and food habits, however, little is known about their dyslipidemia. This study aimed to investigate the prevalence of dyslipidemia and risk factors of this population. A cross-sectional study of dyslipidemia was conducted in 876 Tibetan monks and 912 local residents in the same area. All subjects underwent interviews and physical examinations. The total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) of the subjects were analyzed. Compared to local residents, the overall prevalence of dyslipidemia in monks was 29.5%, which was significantly lower (p<0.05). It was increased with higher age and BMI, but reduced with higher educational level (p<0.05). The typical forms of dyslipidemia in monks were elevated TG and low HDL-C, while it was lower HDL-C in residents (p<0.05). Our study demonstrated that monks in Gannan Tibetan autonomous district had a lower prevalence of dyslipidemia. It suggested that the relatively healthy lifestyle and food habits of monks were mainly responsible of the lower prevalence of dyslipidemia.
Retrouver et comprendre les textes perdus des historiens arabes : l’exemple du
Kitāb al-Futūḥ
de ʿĪsā b. Muḥammad b. Sulaymān b. Abī al-Muhāǧir
Authors: Mkacher Anis
Published: May 2020

This paper tries to explore the origin of an Ifrīqiyan historical school active in the middle of the 9th century throughout the unfortunately lost work of the chronicler ʿĪsā b. Muḥammad b. Sulaymān b. Abī l-Muhājir Dīnār. This paper opens with a gathering of all the excerpts of this list work which have been copied by other writers. Apart from the study of the historical importance of those “new” fragments, we’ll try to understand the nature of this work and the strategies of its composition.
Sunnifying ʿAlī: Historiography and Notions of Rebellion in Ibn Kathīr’s
Kitāb al-Bidāya wa-l-nihāya
Authors: Hagler Aaron
Published: May 2020

In the era of the “Sunnī Revival” and the couple of centuries following, scholars engaged in a large historiographical project aimed at rehabilitating the reputation of the Umayyad dynasty and Syria’s role in the early Islamic narrative. One of Ibn Kathīr’s historiographical missions in his history Kitāb al-Bidāya wa-l-nihāya was specifically the defense of the Companions of the Prophet. As such, the narrative of ʿAlī ibn Abī Ṭālib required some manipulation to answer Shīʿī narratives that cast some of the most important Companions (especially those associated with the Umayyads and Syria) in a rebellious light. This article explores the literary-narrative strategies Ibn Kathīr employs to alter the narrative so as to counteract the implications of the pro-ʿAlīd versions of the story he found in his sources, especially al-Ṭabarī’s Taʾrīkh al-Rusul wa-l-mulūk.
The Effect of Reflow Temperature on Time at the End of Gravity Zone (Tgz) of Sn-3.8Ag-0.7Cu Solder Alloy
Authors: Panikar Ramanandan Santhanu , Skanda V. Amogha , Tikale Sanjay , Prabhu K. Narayan
Published: May 2020

The reflow time for solder until the end of the gravity zone (Tgz) is considered to be the optimum reflow time for obtaining high mechanical performance from lead-free solders. In the present work, the effect of reflow time and temperature on Tgz of Sn-3.8Ag-0.7Cu (SAC387) lead-free solder alloy reflowed on the copper substrate has been investigated. The evolution of interfacial microstructure and solder bond shear strength under different reflow temperatures and time was assessed. Solder balls weighing 0.08 ± 0.01 g were reflowed at 260°C, 280°C, and 300°C for reflow times of 30 s, 60 s, 120 s, and 240 s. Times at the end of the gravity zone for SAC387 solder were obtained as 110 ± 5 s, 55 ± 5 s, and 23 ± 3 s for reflow temperatures of 260°C, 280°C and 300°C, respectively. The contact angle for SAC387 solder on the copper substrate at Tgz was found to be 25.5° ± 0.2° for all reflow temperatures. Scanning electron microscopy revealed the formation of a Cu6Sn5 intermetallic compound (IMC) layer at the interface. The IMC layer thickness increased with increase in reflow temperature and time. Maximum solder joint strength was obtained at Tgz reflow times for all reflow temperatures. Microstructures of samples reflowed beyond the gravity zone showed secondary Cu6Sn5 precipitation in the solder bulk. The present investigation reveals a reduction in Tgz reflow time for SAC387 lead-free solder at higher operating reflow temperatures.
TRANSFORMAÇÃO SOCIAL POR MEIO DA EXTENSÃO UNIVERSITÁRIA: O CASO DO PROJETO MURAL CONTÁBIL ITINERANTE
Authors: Silva Bethânia Batista Carneiro da , Santos Josiane Silva Costa dos , Ribeiro Magno Alves
Published: May 2020

Projetos de extensão universitária são fundamentais, pois geram o diálogo entre a Universidade e sociedade compartilhando conhecimentos e saberes. Neste sentido, a pesquisa objetiva apresentar como o projeto de extensão Mural Contábil Itinerante vem realizando integração entre a universidade e alunos do ensino médio. Trata-se de uma pesquisa descritiva com abordagem qualitativa de dados. O projeto tem como meta envolver todas as escolas do nível médio do município de Tangará da Serra – MT e região. A equipe envolve professores e acadêmicos (1º à 8º semestre) do curso de ciências contábeis e também acadêmicos da pós-graduação. A apresentação inicial do projeto aconteceu na XIV Semana de Contabilidade – SECIC. Previamente, uma banca selecionou alguns artigos acadêmicos, para confecção de pôsteres. Estas pesquisas foram expostas no evento que divulgou a ideia inicial do projeto. Posteriormente, foram realizadas visitas nas escolas de ensino médio e exposição dos pôsteres elaborados pelos acadêmicos. Alguns artigos foram apresentados retratando a contribuição da pesquisa para a sociedade local. Nos encontros ainda foram abordados os indicadores da Universidade, cursos oferecidos e também sobre a profissão do contador e leque de oportunidades que a mesma possibilita. Além de palestras, realizou-se debates com os estudantes a fim de conhecer a percepção dos mesmos em relação ao ensino superior, sonhos, realidades e planos para alcançar tais metas. Assim, a extensão possibilitou motivar a vida destes jovens e adolescentes ampliando horizontes, no que tange a universidade pública, bem como dos acadêmicos na escrita científica, permitindo enriquecer os saberes destes grupos sociais.
EXTENSÃO E PESQUISA UNIÃO ESSENCIAL NA PROMOÇÃO DA QUALIDADE DE VIDA DE PEQUENOS ANIMAIS
Authors: Lima Camila Moura de , Piñeiro Martha Bravo Cruz , Krug Fernanda Dagmar Martins , Britto Risciela Salardi , Ferraz Alexsander , Nobre Márcia De Oliveira
Published: May 2020

A extensão universitária é de grande importância no âmbito acadêmico, pois promove a geração de novos conhecimentos, surgimento de novas modalidades de pesquisa e a oportunidade de integrar a teoria com a prática. Ademais a interação universidade-comunidade auxilia diálogos entre ambos os lados e contribui para o desenvolvimento de atividades sócio-educativas. Nesse contexto, é de grande relevância realizar ações extensionistas na área de saúde animal, a fim de disseminar informações para a prevenção de enfermidades de pequenos animais e medidas de controle de doenças chamadas zoonoses. Com isso, o projeto de ensino, pesquisa e extensão em clínica médica de pequenos animais da Universidade Federal de Pelotas (ClinPet –UFPel) realizou atividades extensionistas tendo como foco informar aos tutores sobre cuidados com a saúde de animais de companhia e também sobre o controle e prevenção de enfermidades e doenças com potencial zoonótico com a abordagem direta dos tutores assim como flyers, folders e redes sociais on line. Além do atendimento clínico geral, o grupo desenvolveu atendimento específico relacionado a pacientes geriátricos, obesos, feridas cutâneas e doenças do conduto auditivo. A equipe também realiza um programa de guarda responsável com esclarecimento sobre o controle populacional de cães e gatos, cuidados necessários e estimulação da adoção. Conclui-se, que as ações extensionistas realizadas pelo ClinPet são de grande importância, pois possuem uma repercussão importante para a sociedade e auxiliam na prevenção, manejo e controle de enfermidades de pequenos animais.
Extensão Universitária e Pesquisa em Diálogo com a Sociedade
Authors: Michelon Francisca Ferreira
Published: May 2020

Dimensões ou especificidades? Há tanta diferença entre a extensão e a pesquisa universitária? Pelo conteúdo dos textos que formam este número da Expressa Extensão, talvez a conclusão seja que ambas participam de uma mesma circunstância: a formação de um profissional capaz de enxergar na realidade social os problemas que precisam ser enfrentados. Se assim for, apenas quando a ciência é aplicada estará próxima desta relação direta com a sociedade que é, em si, o fundamento, o estilo e o princípio diretor da extensão. No entanto, se a ciência básica é vista como um estágio onde surgem novas teorias, então toda a pesquisa é ciência básica e, portanto, a ciência aplicada é apenas uma consequência ou possibilidade da primeira. Alguns até dirão que a ciência aplicada é a dimensão extensionista da formação do estudante. E, hoje, tudo indica que é consensual que a ciência esteja a favor ou trabalhando para o desenvolvimento, ainda que o próprio conceito de desenvolvimento demande ser esclarecido. Vamos entendê-lo, aqui, como o percurso que ocorre para que a vida das pessoas melhore. Assim, desenvolvimento não é um fim, mas um trajeto.