bluuebunny/crossref_metadata_2025 huggingface dataset:
Mineral Composition, Phytochemicals and Anti-microbial Activity of Coconut Water (Cocos nucieferal) on Candida albicans and Lactobacillus acidophilus
Authors:   Department of General Studies, Federal College of Animal Health and Production Technology, Vom, Plateau State Nigeria., Otor Dorathy , Otor Matthew ,   Biochemistry Division, National Veterinary Research Institute Vom, Plateau State Nigeria, Okafor Nonye , Darlington Kate ,   Research and Development, National Veterinary Research Institute Vom, Plateau State Nigeria., Adima OS ,   Plant and Laboratory Equipment Maintenance Division, National Veterinary Research Institute Vom, Plateau State Nigeria.
Published: July 2021

The phytochemicals and anti-microbial activity of coconut water on Candida albicans and Lactobacillus acidophilus and also its mineral composition were investigated for its medicinal potential. The study revealed the presence of Pb, Cu, Zn, Cd, Fe, Ca, Na, K, Mg and Mn. The concentration of the elements in ppm were as follows Pb (0.058), Cu (0.012), Zn (0.202), Cd (0.028), Fe (0.109), Ca (0.368), Na (1.300), K (1.740), Mg (0.947), Mn (0.229). Saponins, alkaloids, steroids, cardiac glycosides and carbohydrates were the phytochemicals detected. The coconut water was tested against Candida albicans and Lactobacillus acidophilus using Agar well diffusion method. Inhibitory zone diameter ranges from 13-25 mm. The results showed a concentration-dependent antimicrobial activity against the tested organisms. Inhibitory activity exhibited by coconut water against these micro-organisms is an indication of the presence of bioactive compounds which can be identified, isolated and incorporated into modern oral care systems for controlling dental caries. Keywords: Coconut water, phytochemicals, Candida albican, Lactobacillus acidophilus
Diversidad faunística y potenciales agentes tafonómicos en el Chaco árido (Córdoba, Argentina): una aproximación preliminar con cámaras trampa
Authors: Weihmüller María Paula , Costa Thiago , Castro Lucila Belén , Barri Fernando Rafael
Published: July 2021

El objetivo de este trabajo consistió en identificar las principales especies animales que actúan sobre carcasas de ungulados de gran porte en un área cercana al extremo austral de las Salinas Grandes de Córdoba y su potencial como agentes tafonómicos, considerando variables ecológicas como etología, competencia y posición en la cadena trófica. Con este fin, se realizaron tres monitoreos con cámaras trampa sobre carcasas de Bos taurus y Lama guanicoe. Además, se efectuaron observaciones preliminares sobre desarticulación, dispersión y trazas generadas por distintos agentes tafonómicos sobre las carcasas, a fin de contribuir a nuestro entendimiento sobre los procesos naturales de formación de conjuntos zooarqueológicos en la región. Los monitoreos permitieron registrar 5870 animales en 194 días entre noviembre de 2017 y mayo de 2019. Aves (77,13%) y mamíferos (22,84%) fueron las clases mejor representadas. Entre las aves, se destacan Coragyps atratus, Caracara plancus, Vultur gryphus y Milvago chimango, mientras que entre los mamíferos destaca Lycalopex griseus y las especies exóticas Sus scrofa y Canis lupus familiaris. Se observaron diferencias entre los ensambles faunísticos registrados en cada monitoreo en función del tiempo transcurrido desde la muerte de los animales y de su ubicación espacial.
PENGARUH EKUITAS MEREK DAN PERILAKU KONSUMEN TERHADAP KEPUTUSAN PEMBELIAN ULANG PRODUK MINYAK GORENG PADA MASA PANDEMI COVID-19
Authors: Fadhli Khotim , Dwi Aprilia Elsa , Angga Putra Ino
Published: July 2021

This study aims to determine the effect of brand equity and consumer behavior on repeat purchases. This type of research uses quantitative research. The data collected in this study used questionnaires or submitted written questions to collect data from respondents with a total of 79 respondents. Respondents were taken from the customers of the Mitra Swalayan Jombang store. The data were processed using multiple linear regression analysis using the SPSS version 26 computer program. This study showed positive and significant results from the influence of brand equity variables (X1) and consumer behavior (X2) on the repurchase variable (Y). Brand equity against repurchase is a component that must exist. Because brand equity will make the product attractive to consumers and people are looking for to consume again. Consumer behavior towards repurchase is something that must be known by a marketer in order to understand how consumers make decisions or choose the goods to be purchased. Based on the results of this study, several conclusions can be drawn, that brand equity and consumer behavior variables affect repeat purchases at Mitra Swalayan Jombang.
Modeling the Choice of the Innovation and Investment Strategy for the Implementation of Modernization Potential
Authors: Vovk Olha , Kravchenko Maryna , Popelo Olha , Tulchynska Svitlana , Derhaliuk Marta
Published: July 2021

Since modernization challenges of microeconomic systems are implemented through strategic management of the modernization potential development of enterprises, the rationale for choosing an exclusive innovation and investment strategy is proposed. An algorithm for making managerial decisions based on the model of "preferences in the implementation of investment and innovation strategies" ("PIIIS") is built. The model is based on the concept of strategic management, economic and mathematical hierarchy of potential levels of cognitive judgment, optimization of resources on demand and the structure of innovation and investment strategies. This allows to ensure the efficiency and resource conservation of individual innovation and investment strategies in modernization potential of the enterprise. The sequence of establishing preferences of innovation and investment strategies for activating modernization potential of microeconomic systems is proposed. To model the process of granting preferences to innovation and investment strategies, a system of coefficients based on the potential profile level using cognitive judgments is substantiated. Resource-providing, accumulating, implementation and resulting levels of the modernization potential development are singled out. According to the profile levers, target tasks and alternatives of preferences of innovation and investment strategies for the modernization potential development are identified. Decomposition of tasks of granting preferences to innovation and investment strategies to intensify modernization potential of microeconomic systems is substantiated. It is proposed to use mathematical tools for the analysis of hierarchies, based on mathematical and cognitive judgments based on the T. Saaty model. Application of the Pareto model for the distribution of the coefficients influence in the effectiveness of the components analysis of the potential profile is presented. The choice of innovation and investment strategies for the modernization potential development for enterprises in the infrastructure sector of Ukraine is analyzed and determined.
Legal support for the activities of agricultural transnational corporations in Ukraine
Authors: Shulga Mykhaylo V. , Korniyenko Ganna S. , Yakoviyk Ivan V.
Published: July 2021

Agricultural transnational corporations have always expressed interest in Ukraine as a state with a strong natural potential and good and reliable prospects for agribusiness. Under the influence of factors such as climate change, an unprecedented increase in the world's population and, as a result, a high demand for agricultural products, this interest will increase, and the role of agricultural transnational corporations will grow every year. Therefore, one of the most urgent research and practical problems that lawyers will have to solve is the definition of the key term “agricultural transnational corporations” and the identification of their features. This will allow the Ukrainian legislator to regulate complex and multidimensional relations with their participation in the agricultural sector as accurately as possible and, in particular, govern relations concerning the activities of these subjects of agricultural business, and eliminate gaps in the current legal regulation. Considering this, the purpose of this study was to attempt establishing the essence of agricultural transnational corporations as a legal phenomenon based on an in-depth analysis and to define this term, classify these corporations on certain grounds and establish the specific features of their activities. The study was conducted considering the existing legal support of these participants in agribusiness relations. Research methods included a set of philosophical, general scientific, and special legal methods. The synergetic research method was the fundamental method of understanding the legal support of agricultural transnational corporations. It was proved that an agricultural transnational corporation is a complex entity that engages in agricultural activities in two or more countries, is managed and controlled from a single centre and comprises a parent company, subsidiaries, branches, and departments. The study analysed positive and negative aspects of the activities of agricultural transnational corporations. It was established out that the following agricultural transnational corporations act in Ukraine: in the field of crop production, animal husbandry, processing, servicing agricultural producers, and with mixed activities (simultaneously engaged in both crop production and animal husbandry). It was emphasised that the agricultural chain of a transnational corporation can cover different countries
Rule of law and state of exception: the genesis of the problem
Authors: Maksymov Sergiy I. , Satokhina Natalia I.
Published: July 2021

The purpose of this study was to clarify the correlation between the concepts of the rule of law and the state of exception in the context of the question of the nature of law and its correlation with force. The relevance of the study is explained by the need to reinterpret the idea of the rule of law and its boundaries in the context of modern challenges, in particular in the context of a pandemic. The study is of an interdisciplinary nature, which lies in combining legal, philosophical legal, and historical-philosophical perspectives using methods of philosophical legal reflection, comparison, analysis and synthesis, and historical-philosophical reconstruction. The correlation between the rule of law and the state of exception was clarified in three steps. First, the fundamental idea of the rule of law was explicated, which unites its numerous interpretations: law was considered as the antithesis of the arbitrariness of the powerful. Accordingly, the rule of law turned out to be a requirement immanent to any legal system. At the same time, the internal limitation of the rule of law associated with the statutory nature of the latter was emphasised, which inevitably necessitates striking a balance between the rule of law and justice, and the radicalisation of which brings to life the idea of a state of exception. The second part of this study contains a critical analysis of the theory of the state of exception, which, in contrast to the idea of the rule of law, identifies law and force, and ultimately denies law as such, normalising lawlessness. Finally, in the third step, three approaches to the correlation between the rule of law and the state of exception were analysed: 1) the priority of the state of exception, 2) a weak version of the priority of the rule of law, and 3) a strong version of the priority of the rule of law. It was concluded that the fundamental opposition between the rule of law and the state of exception renders their consistent combination impossible, and the corresponding attempts always turn out to be a compromise not favouring the former. However, according to the authors of this study, it is necessary to recognise the limitations of the law itself, without abandoning the discourse of the rule of law and the fundamental grounds for it
ORTAOKUL MATEMATİK ÖĞRETMEN ADAYLARININ SENARYO TEMELLİ ÖĞRENME HAKKINDAKİ GÖRÜŞLERİ
Authors: ERCAN Selami , PATAN Özge
Published: July 2021

Bu araştırmanın amacı ortaokul matematik öğretmeni adaylarının senaryo temelli öğrenme (STÖ) hakkındaki görüşlerini belirlemektir. Bu çalışma nitel bir çalışma olarak tasarlanmış ve katılımcıları da 2018-2019 eğitim-öğretim yılının güz döneminde, bir devlet üniversitesinin ilköğretim matematik öğretmenliği bölümünde son sınıfta öğrenim gören beş matematik öğretmen adayıdır. Araştırmaya on iki katılımcı ile başlanmış, süreç sonunda senaryoların uygulanması için uygun şartlara sahip beş öğretmen adayı ile araştırma tamamlanmıştır. Araştırma sürecinde öğretmen adayları ile toplu ve bireysel oturumlar gerçekleştirilmiştir. Öğretmen adayları ile süreç öncesinde görüşülmüş, daha sonra STÖ hakkında bilgilendirme semineri verilmiştir. Senaryo yazma sürecinden geçen adaylarla uygulama öncesinde ve sonrasında görüşmeler yapılmıştır. Yapılandırılmış ve yarı yapılandırılmış görüşme protokolleri ile adayların görüşleri yazılı ve sözlü olarak alınmış, sözlü görüşmeler ses ise kaydı ile muhafaza edilmiştir. Toplanan bu veriler içerik analiziyle analiz edilmiş ve bu yapılırken informal gözlemlerden de yararlanılmıştır. Analiz sonucunda süreç başında öğretmen adaylarının STÖ hakkında herhangi bir bilgiye sahip olmadığı, fakat ‘senaryo’ ve ‘öğrenme’ kelimelerinden yola çıkarak yorumda bulunabildikleri görülmüştür. Ayrıca katılımcılar STÖ’de kullanılacak senaryoların; kazanıma uygun olma, kavram yanılgısına neden olmama, öğrenci seviyesine uygun olma, anlaşılır bir dile sahip olma, eğlenceli olma, günlük yaşamla ilişkili olma, öğrencinin dikkatini çekme, vb. gibi özelliklere sahip olması gerektiğini belirtmişlerdir. Ancak, uygulama esnasında sınıfı yönetmede ve hedeflere ulaşmada sorunlar yaşadıklarını belirtmişlerdir. Öğretmen adaylarının çoğunluğunun; öğrencilerin anlamalarını kolaylaştırma, empati yeteneğini kazandırma, matematik dersini günlük yaşamla ilişkilendirme, konuşma yeteneklerini geliştirme, sorumluluk kazanma, ve kavramları somutlaştırma beklentilerinin karşılanmamasına karşın, hepsi meslek hayatlarında STÖ uygulamaları kullanmak istediklerini ifade etmişlerdir.
La respuesta de prevención como política de salud pública del Estado peruano en el caso de propagación internacional de enfermedades. Un análisis a propósito del COVID-19
Authors:   Universidad Privada Norbert Wiener, Morales Cauti Guisseppi Paul , Camones Alcazar Adriana Abril ,   Universidad Privada Norbert Wiener
Published: July 2021

En la presente investigación se analiza el desarrollo de las políticas públicas a cargo del Estado peruano en materia de prevención de propagación internacional de enfermedades a propósito de la pandemia provocada por el COVID-19. La estrategia de análisis parte de la revisión sistemática de las disposiciones normativas dada por la Organización Mundial de la Salud -especialmente las dictadas mediante el Reglamento Sanitario Internacional-, la Organización panamericana de la Salud y las entidades del Estado peruano encargadas de desarrollar e implementar las políticas públicas de respuesta de prevención y control de la propagación del virus SARS-CoV-2 (COVID-19). Se obtuvo como resultado que el Estado peruano no diseñó ni implementó las políticas públicas como respuesta de prevención en el caso de propagación internacional de enfermedades, conforme lo había exigido la Organización Mundial de la Salud y la Organización Panamericana de la Salud, en documentos oficiales de cumplimiento obligatorio para el Estado peruano. Esta situación ha generado consecuencias negativas posteriores en el contexto de la propagación internacional de la enfermedad del COVID -19 provocando la muerte de ciudadanos peruanos que pudieron evitarse; a tal punto que el Perú es el país con mayor mortalidad en el mundo en el contexto de esta pandemia.
COMPLEMENTARY FEEDING – A SHORT REVIEW OF SEVERAL CORRECT PRINCIPLES OF LONG-TERM HEALTH
Authors:   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Florescu Laura , Temneanu Oana-Raluca ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Mindru Dana-Elena ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Nicolai Nistor ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

Nutrition epitomizes the whole range of physiological processes of absorption and decomposition of food in the body, as required for growth and development. The debates on the feeding trends are topical, a large number of scientific boards and international committees fully concentrate on the impact of correct feeding on growth and harmonious development, starting even from intrauterine life. The progressive introduction of half solid and solid food in the infant’s diet after 4-6 months, gradually replacing the milk meals previously administered is known as diversified (complementary) feeding. The latest recommendations of the ESPGHAN Committee (European Society for Pediatric Gastroenterology, Hepatology and Nutrition) regarding the moment of switching from an exclusively milk diet to a diet which includes other foods is included in the period of time between week 17 and 26. The compliance and the collaboration of the family with the doctors are of paramount importance. Considering the present day open access to a lot of information, sometimes without any scientific basis, we believe it is opportune to review briefly the main aspects of the complementary feeding according to the recommendations in the field.
DIAGNOSIS DIFFICULTIES IN INFANT’S HYPOGLYCEMIA
Authors:   1st Pediatric Clinic, University of Medicine and Pharmacy, Targu-Mures, Grama Alina , Marginean Oana ,   1st Pediatric Clinic, University of Medicine and Pharmacy, Targu-Mures, Velea Iulian ,   1st Pediatric Clinic, University of Medicine and Pharmacy, Timisoara, Paul Corina ,   1st Pediatric Clinic, University of Medicine and Pharmacy, Timisoara, Chincesan Mihaela ,   1st Pediatric Clinic, University of Medicine and Pharmacy, Targu-Mures, Melit Lorena Elena ,   1st Pediatric Clinic, University of Medicine and Pharmacy, Targu-Mures
Published: July 2021

Introduction. Hypoglycemia with its diverse causes is frequently encountered in the pediatrics pathology, beginning with the neonatal period and until the adolescent one. Through its consequences, both, the early (seizures, coma) and the late ones (neurological impairment), hypoglycemia must be identified, prevented, avoided and treated. Objectives. To present the clinical evolution of a female patient with severe, symptomatic hypoglycemia even since the neonatal period. Since birth, the value of glycaemia presents a fluctuant dynamic, and the isolated decrease of glycaemia does not necessary represent a pathological situation, but can be a symptom of an underlying disorder. Material and method. The patient is admitted in our clinic at the age of newborn in order to establish the etiology and treatment of hypoglycemia. We achieved the biologic and hormonal profile, we performed metabolic blood determinations and genetic tests. Results. We established the diagnosis of severe persistent hypoglycemia. The burden of the results interpretation was represented by the prolonged evolution of the disease, the small age and the family’s low compliance. Conclusions. Persistent hypoglycemia has multiple causes. The management of an infant with severe hypoglycemia can be difficult and it imposes a complex approach.
TYPE 2 GAUCHER DISEASE: ONSET AND EVOLUTION – CASE REPORT
Authors:   1st Pediatric Clinic, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Streanga Violeta , Jitareanu Cristina ,   1st Pediatric Clinic, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Ciomaga Irina M. ,   1st Pediatric Clinic, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Mihaila Doina ,   Department of Pathological Anatomy, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Nistor Nicolai ,   1st Pediatric Clinic, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

Gaucher disease is the most common lysosomal storage disorder, with autosomal recessive transmission. The disease is due to glucocerebrosidase enzyme deficiency, resulting in accumulation of glucocerebroside in all organs. The diagnosis is established by measuring enzyme activity. Among the clinical forms, type 2 is the rarest and has the most dismal prognosis. We present the case of an infant found at 5 months of age with neurological symptoms and his subsequent evolution with massive hepatosplenomegaly, being diagnosed with type 2 Gaucher disease.
NEURONAL MIGRATION DISORDER – A CLINICAL CASE
Authors:   “Alfred Rusescu” Institute for Mother and Child Care, Bucharest, Voicila Carmen , Cabat Anca ,   “Alfred Rusescu” Institute for Mother and Child Care, Bucharest, Ioan Raluca Gabriela ,   “Alfred Rusescu” Institute for Mother and Child Care, Bucharest
Published: July 2021

The authors present the case of a newborn transferred to the Neonatology Section of IOMC Polizu, 43 hours after birth suffering from syndrome of neonatal respiratory distress and suspicion of maternal – fetal infection, extensively investigated during hospitalization for persistency of muscle tone disorder which could not be explained by asphyxia at birth, diagnosed after MRI with right periventricular heterotopia associated with left temporal porencephalic cyst and schizencephaly on the same side.
ALIMENTAŢIA DIVERSIFICATĂ – SCURTĂ TRECERE ÎN REVISTĂ A UNOR PRINCIPII CORECTE PENTRU O SĂNĂTATE PE TERMEN LUNG
Authors:   Universitatea de Medicinǎ şi Farmacie „Gr. T. Popa“, Iaşi, Florescu Laura , Temneanu Oana-Raluca ,   Universitatea de Medicinǎ şi Farmacie „Gr. T. Popa“, Iaşi, Mîndru Dana-Elena ,   Universitatea de Medicinǎ şi Farmacie „Gr. T. Popa“, Iaşi, Nicolai Nistor ,   Universitatea de Medicinǎ şi Farmacie „Gr. T. Popa“, Iaşi
Published: July 2021

Nutriţia reprezintă totalitatea proceselor fiziologice de asimilare şi degradare a alimentelor care au loc într-un organism, necesare creşterii şi dezvoltării. Se menţin de actualitate discuţiile asupra tendinţelor în alimentaţie, numeroase societăţi ştiinţifice şi comitete internaţionale dedicându-şi atenţia asupra impactului pe care alimentaţia corectă o are asupra creşterii şi dezvoltării armonioase, începând încă din viaţa intrauterină. Introducerea progresivă în alimentaţia sugarului, după vârsta de 4-6 luni, a alimentelor semisolide şi solide, ce înlocuiesc treptat prânzurile de lapte administrate anterior este cunoscută sub denumirea de alimentaţie diversificată (complementară). Ultimele recomandări ale Comitetului ESPGHAN (European Society for Pediatric Gastroenterology, Hepatology and Nutrition) privind momentul trecerii de la o alimentaţie exclusiv lactată la una care să conţină şi alte alimente sunt pentru intervalul de vârstă cuprins între săptămânile 17-26. O importanţă primordială o are complianţa şi colaborarea familiei cu medicii. Având în vedere posibilitatea actuală de a accesa numeroase informaţii, uneori fără o bază ştiinţifică, am considerat oportună o scurtă trecere în revistă a principalelor aspecte ale unei alimentaţii diversificate conform recomandărilor de specialitate.
DEBUT ŞI EVOLUŢIE ÎNTR-UN CAZ DE BOALĂ GAUCHER TIP 2
Authors:   Clinica I Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ştreangă Violeta , Jităreanu Cristina ,   Clinica I Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ciomaga Irina M. ,   Clinica I Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Mihăilă Doina ,   Serviciul de Anatomie Patologică, Spitalul de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Nistor Nicolai ,   Clinica I Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: July 2021

Boala Gaucher este cea mai frecventă maladie lizozomală, cu transmitere autosomal recesivă. Boala se datorează deficitului enzimei glucocerebrozidază, rezultând în acumularea de glucocerebrozide în toate organele. Diagnosticul se stabileşte prin măsurarea activităţii enzimei. Dintre formele clinice, tipul 2 este cel mai rar şi are prognosticul cel mai sumbru. Prezentăm cazul unui sugar depistat la vârsta de 5 luni cu simptome neurologice şi evoluţia lui ulterioară cu hepatosplenomegalie masivă, fiind diagnosticat cu tipul 2 de boală Gaucher.
MUNCHAUSEN SYNDROME BY PROXY – A REAL PEDIATRIC PROBLEM?
Authors:   Pediatric Clinic, “Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest, Pacurar Daniela , Runcan Maria ,   Pediatric Clinic, “Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest, Popescu Anca ,   Pediatric Clinic, “Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest, Lesanu Gabriela ,   Pediatric Clinic, “Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest, Oraseanu Dumitru ,   Pediatric Clinic, “Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest
Published: July 2021

Munchausen syndrome and Munchausen by proxy syndrome belong belong to a group of disease called “factitious disorder” and are severe mental disorders having the “end” position for a healthy person to become patient, respectively to “create” a disease to another person, asking or requiring medical intervention for him/her. Munchausen syndrome by proxy is rare, but it is difficult to be recognized and confirmed, is a form of abuse, particularly against children, potentially lethal, often misunderstood. Many methods are used by adults counterfeiters to induce a false child’s condition: poisoning, injury, producing bleeding, infection. Complaints exposed by the mothers as belonging to the child are not for a personal benefit, but are justified by a desire to be a “hero” mothers and to play the role of the people most attached and thoughtful of their child. Diagnosis should include evaluation of the child, parents and family and is based on suggestive elements: child with multiple health problems that do not respond to treatment or recur under proper therapy, laboratory investigations discrepancies, child’s signs and symptoms disappear in the absence of the parent. The false disease of the child, intentionally distorted described by adult, do not really affect him/her, but the diagnostic process and medical treatment can cause pain and discomfort. Ethical and legal issues associated with MSBP involves healthcare professionals by the medical consequences on the child as a result of false complains described by the parent. Education of patient, family and medical personnel is a very important step in the recognition, prevention and treatment of MSBP.
PECULIARITIES OF DIAGNOSIS AND TREATMENT OF THE ESOPHAGEAL FOREIGN BODIES (COINS) IN CHILDREN – CLINICOSTATISTICAL STUDY
Authors:   National Institute of Neurology and Neurovascular Diseases, Bucharest, Toader Corneliu ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Toader Miorita ,   “Grigore Alexandrescu” Emergency Hospital for Children, Bucharest, Vivisenco Iolanda Cristina ,   “Grigore Alexandrescu” Emergency Hospital for Children, Bucharest,   “Carol Davila” University of Medicine and Pharmacy, Bucharest
Published: July 2021

Objective. The authors performed a clinical and statistical study on cases of esophageal foreign bodies, with particular reference to ingested coins, admitted and treated in the ENT Department of the “Grigore Alexandrescu” Emergency Hospital for Children, between 01.01.2006 – 01.08.2007. Method and materials. A retrospective study, involving the interpretation and corroboration of the clinical and paraclinical findings of each case study. Results. Of all cases of foreign bodies, coins held the highest percentage; the average length of stay in hospital was 2 days; there were no cases of major complications (esophageal perforation, bleeding by intercepting a large vessel, mediastinitis); were also recorded particular cases that required special attention. Conclusion. All cases were approached and resolved by rigid endoscopy; shortening the time elapsed before presenting to ENT specialist facilitates the therapeutic approach, dramatically lowering the risk of complications; X-ray examination, although essential, can sometimes provide incomplete information, the diagnosis certainty being ensured only by endoscopy.
CONCOMITANT INGESTION OF ETHYLENE GLYCOL AND ETHANOL: A DIAGNOSIS TRAP?
Authors:   Pediatric Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Frasinariu Otilia-Elena ,   “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Rugina Aniela ,   Pediatric Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi,   “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Jitareanu Cristina ,   “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Russu Radu ,   “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Nistor Nicolai ,   Pediatric Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi,   “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Streanga Violeta ,   Pediatric Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi,   “Sf. Maria” Emergency Clinical Hospital for Children, Iasi
Published: July 2021

Ethylene glycol is one of the most toxic alcohols; it may be accidentally or intentionally consumed as a substitute for ethanol or related to suicidal attempts. Ingestion of ethylene glycol causes a severe metabolic acidosis with increased anion and osmotic gap due to its toxic metabolites, leading to a clinical picture of central nervous system depression, cardiovascular and renal impairment. A 16-year-old boy was admitted with clinical and biological signs of ethylene glycol poisoning after simultaneous ingestion of antifreeze and ethanol. The patient had mild anion gap metabolic acidosis only at the debut, rapidly corrected with one dose of sodium bicarbonate; further evaluation did not reveal acidosis, even if the subsequent evolution included acute renal failure requiring hemodialysis. Due to the absence of a positive history and of a persistent metabolic acidosis, the diagnosis of ethylene glycol poisoning was delayed until it was confirmed by serum toxicological test. Conclusions: concomitant ingestion of ethanol may mask the symptoms of ethylene glycol poisoning; the absence of persistent metabolic acidosis does not rule out the diagnosis.
PRE-PROCEDURAL RECOMMENDATIONS IN PEDIATRIC GASTROINTESTINAL ENDOSCOPY
Authors:   Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Diaconescu Smaranda , Paduraru Gabriela ,   Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Olaru Claudia ,   Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Gimiga Nicoleta ,   Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Soponaru Camelia ,   “Al. I. Cuza”, University, Iasi, Ciubara Anamaria ,   Psychiatry, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Bolat Maria ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Iorga Magdalena ,   Psychology, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

Gastrointestinal endoscopy is one of the most common invasive procedures carried out in pediatric gastroenterology and is not without risk. The range of necessary measures for the purpose of this procedure includes: the accurate assessment of the patient considering the endoscopy-related indications and contraindications, obtaining the informed consent, the psychological preparation of the parents/child, applying some dietary restrictions, and infection prophylaxis. It is also necessary to choose the type of sedation and ensure the constant monitoring during and after the procedure so as to avoid any complications related to the procedure or to the side effects of drugs.
ULCERUL GASTRIC DUPĂ ADMINISTRAREA PE TERMEN SCURT DE ANTIINFLAMATOARE NESTEROIDIENE LA UN COPIL MIC – PREZENTARE DE CAZ
Authors:   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ignat Ancuţa , Păduraru Gabriela ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Marin Angelica Cristina ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ciubară Anamaria ,   Disciplina Psihiatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Lupu Valeriu V. ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Burlea Marin ,   Disciplina Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: July 2021

Agenţii antiinflamatori nesteroidieni (AINS) produc leziuni gastrice prin intermediul a două mecanisme: iritaţia locală şi acţiunea sistemică. Un copil în vârstă de 2 ani şi 10 luni, sex feminin, a primit AINS timp de 2 zile pentru o infecţie acută a tractului respirator superior şi a prezentat vărsături în „zaţ de cafea“ o zi mai târziu. Endoscopia digestivă superioară a evidenţiat o leziune de ulcer gastric. Biopsia gastrică a fost negativă pentru infecţia cu H. pylori, iar pacienta a fost diagnosticată cu ulcer gastric acut indus de consumul de AINS în absenţa altor cauze de ulcer gastric. Ulcerele gastrice se dezvoltă foarte rar după o administrare pe termen scurt de AINS, fapt ce a determinat raportarea acestui caz. Luând în considerare atât riscurile cât şi beneficiile terapiei cu AINS, este indicat ca în cazul fiecărui pacient care trebuie să urmeze un tratament cronic cu medicamente antiinflamatorii să fie căutaţi posibilii factori de risc asociaţi.
CLINICO-DEMOGRAPHIC PATTERNS OF DEPRESSION AND ANXIETY IN CHILDREN AND ADOLESCENTS
Authors:   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Ciubara Anamaria , Chirita Roxana ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Burlea Stefan Lucian ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Ignat Ancuta ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Diaconescu Smaranda ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Untu Ilinca ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Lupu Valeriu V. ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

In both adults and pediatric population, depression is a major disability cause; suicide is the third death cause among children and adolescents. Whereas depression and depression with associated anxiety are among the most common psychiatric pathologies in children and adolescents (with strong impact on their global functionality and with a significant influence on their development process), they are far from studied thoroughly. This study aims to highlight certain demographic and clinical patterns associated to depression of anxiety in children and adolescents, which may represent premises for broader future research and for the consolidation of primary, secondary, and tertiary prevention methods.
GASTRIC ULCER AFTER SHORT-TERM NONSTEROIDAL ANTI-INFLAMMATORY DRUGS ADMINISTRATION IN A SMALL CHILD – CASE REPORT
Authors:   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Ignat Ancuta , Paduraru Gabriela ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Marin Angelica Cristina ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Ciubara Anamaria ,   Psychiatry Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Lupu Valeriu V. ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Burlea Marin ,   Pediatrics Department, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

Nonsteroidal anti-inflammatory agents (NSAIDs) produce gastric lesions through two mechanisms: local irritation and systemic action. A 2 year and 10 months old female received NSAID for acute upper respiratory infection for 2 days and she developed coffee ground vomitus one day later. Upper gastrointestinal endoscopy revealed a gastric ulcer. She was negative for H. pylori infection, and she was diagnosed with NSAID – induced acute gastric ulcer in the absence of other causes of gastric ulcer. Gastric ulcers develop very rarely after a short-term administration of NSAIDs, which prompted us to report this case. Balancing the risk and the benefit of eradication therapy, it is indicated, for every patient who must follow a chronic treatment with anti-inflammatory drugs, to look for possible associated risk factors.
The concept of global public goods in contemporary international relations between Russia and China
Authors: Kononkova Natalia , Bulgakova Yulia , Kuznetsova Natalia , Prokhodtseva Yulia , Ustiuzhanina Maria
Published: July 2021

The research concentrates on the development of the concept of global public goods in Russia and China, while new economic grounds are emerging, including a shift to digital economy and the COVID-19 pandemic. This concept is analyzed with a special emphasis on joint Russian-Chinese projects. The analysis is supplemented by a classification based on the financing of global public goods. The findings of our research show that the vast majority of global public goods are financed by governments, even though such global threats as pandemics require donations, as well as further actions by all possible investors. According to the results, with the rapid development
of digitalization, most initiatives are aimed at encouraging the spread of digital technologies. The findings of the research suggest implications for figuring out who may have a special interest in the financial aspect of the concept of global public goods.
Motivation and factors affecting motivation among nurses in Ho Chi Minh blood transfusion and hematology hospital in 2020
Authors:   Blood Transfusion and Hematology Hospital, Ho Chi Minh city, Duong Ngoc Phuong Trang , Bui Thi My , Nguyen Duc Thanh
Published: July 2021

The study aimed to describe the motivations of nurses and determine factors influencing motivation of nurses in Ho Chi Ming blood transfusion and hematology hospital in 2020. The research methodology is cross-sectional descriptive study, combining quantitative and qualitative method, sample size is 104 nurses. The results showed that the working motivation among nurses in hospital accounted for 72.1%. The average score of working movitation was at 3.9/5. The factors such as age, marital status, income were found a significantly association with the nurses’ working motivation (p<0.05). Moreover, the factors including working condition, trainin opportunity had a positive effect to the nurses’ working motivation. Otherwise, working assign and working performance assessment were negative effects to working motivation among nurses in hospital. Keywords. Working motivation, nurses, Ho Chi Minh,…..
Time series regression to identifying the relationship between air pollution and health in Vietnam
Authors:   Hanoi University of Public Health, Nguyen Thuy Linh , Le Tu , Nguyen Thi Kim Ngan , Nguyen Thi Bich Lien , Nguyen Thi Trang , Tran Minh Dien
Published: July 2021

Time series has been widely used in environmental epidemiology; especially in identifying the short-term associations between ambient air pollution and health outcomes. For both exposure and outcome, data are available at regular time intervals (daily hospital admissions and pollution levels) to explore short-term associations between them. In this article, we described main steps to conduct time series regression and highlighted some key ideas when applying this technique. A sample data was used to investigate short-term association between PM10 and daily hospital admission among children in Hanoi between 2008 and 2016. This analysis was conducted with R software. Keywords: time series, air pollution, short-term effect
Occupational stress and associated factors among clinical nurses from Hung Vuong and Tu Du hospitals, who are studying bachelor degree, in 2019
Authors: Nguyen Thai Quynh Chi , Le Minh Sang
Published: July 2021

This cross-sectional study using quantitative and quailitative methods conducted among clinical nurses from Hung Vuong and Tu Du hospitals, who are studying bachelor degree at Nguyen Tat Thanh University. The study was implemented from April to August 2019 and aimed at describing occupational stress of clinical nurses and associated factors. Quantitative data (applying Enxpanded Nursing Stress Scale) were collected from 232 nurses and analyzed by SPSS 20.0. Qualitative information from 02 focus group discussions were analyzed by themes. Results showed that occupational stress of clinical nurses was moderate (with total average score of 2.14). The most 3 stressful components were: Facing the patient fatality, Issues related to the patients’ relatives, Workload. Asociated factors included: individual, family, and studying factors. Key words: occupational stress, nursing, working-studying nurse, ENSS
Assessment of food safety conditions of bottled drinking establishments in Can Tho city in 2020
Authors:   Can Tho City Food Safety and Hygiene Department, Than Ngoc Ha , Nguyen Thanh
Published: July 2021

Objectives: The main objectives were the evaluation of food safety conditions, the determination of the rate of microbiological contamination in bottled drinking water at Can Tho city in 2020. Methods: Samples were collected from 116 factories with 58 samples of bottled water during a period of time (from February 2020 to May 2020). Results: The ratio that met the criteria for food safety conditions was 44,0% (51/116). The ratio for microbiological contamination was 39,7% (23/58). Conclusions and recommendations: The ratio that met the criteria for food safety conditions is low and the ratio for microbiological contamination is quite high. From the these results, it can be recommended thatirregular inspection of production facilities which have problems of microorganisms should be applied; and the frequency of periodic inspection should increase (e.g. 2 times/year) for factories where do not maintain food safety conditions according to regulations. Keywords: Bottled drinking water, microbiological contamination, food safety.
Evaluate the results and the advantage and disadvantages of the food safety project performance during 2016 – 2020
Authors:   Hanoi University of Public Health, Luu Quoc Toan , Nguyen Thanh , Bùi Thi Thu , Le Thi Vui , Duong Minh Duc , Bui Thi Tu , Nguyen Thi Kim , Le Bao Chau
Published: July 2021

The objective of study: The research aimed to discrible results and the advantage – disadvantages of the Project 4 - Food Safety that wer under the Health - Population Program during 2016 – 2020. Study design: A cross-sectional, combining quantitative and qualitative study was conducted. Study sites: in 7 provinces / cities, from October 2019 to August 2020. Study subjects: the project activity reports and the staff of the Project 4 - Food Safety. Results: The results showed that 8 indicators of the project have been completed according to the goals, 2 indicators are expected to be completed after the end of the project. In which, 100% of provinces/cities had ISO/IEC 17025 laboratory for food safety and pilot food safety-model markets. The incidence rate of food poisoning ranged from 1.82 to 4.92 per 100,000 people. The main limitations during project implementation were the lack of human resources, funding and overlap in state management assignments for food safety at the local goverment levels. Conclussion: The Project 4 - Food Safety basically achieved the setting targets. Keywords: Food safety, Health – Population programe, food safety management
Assessment of single nucleotide polymorphism RS2596542 of MICA gene among nasopharyngeal cancer patients
Authors:   Hanoi Medical University, Nguyen Phuong Thoa , Vu Hai Linh , Nguyen Van chu , Nguyen Huu Quoc , Nguyen Kim Dong , Luong Viet Hung , Nguyen Thi Tinh , Nguyen Hoang Viet
Published: July 2021

MICA is an antigen that is commonly expressed on cell surface of tumoRS. MICA had a low expression level in normal cells but increased in pathological/cancer cells. The goal of the study was to determine the association of SNP RS2596542 with the risk of nasopharyngeal cancer (NPC). 144 biopsy samples diagnosed with NPC and 135 blood samples from healthy people were collected. Genotypes and alleles of RS2596542 MICA were determined by Realtime PCR genotyping. The genotype rate of MICA at RS2596542 in patients with NPC was 34.72% CC; 44.44% CT and 20.84% TT. The genotype of TT and T allele in the disease group was significantly higher than the control group (p=0.01*; OR=2.47; 95%CI: 1.22-4.97) and (p=0.01*; OR=1.51; 95%CI: 1.07-2.13). The T-allele at SNP RS2596542 of the MICA gene increases the risk of NPC and suggests that this could be used as a biomarker for NPC screening in Viet Nam. Keywords: MICA, RS2596542, nasopharyngeal cancer, NPC, Single Nucleotide Polymorphism, SNPs, Realtime PCR
Disrupting Nursing Education in Light of COVID-19
Authors: Weberg Daniel , Chan Garrett , Dickow Mary
Published: July 2021

Healthcare and health professions education is at the moment of a paradigm shift. The traditions of our institutions, such as in person courses and clinical experiences, are under tremendous strain. The COVID-19 pandemic, and sudden shift to almost fully online coursework, has provided a catalyst for new methods of nursing education for our profession. Crisis creates significant energy and can generate solutions to past barriers. Nursing education continues to be disrupted by the current events that require new thinking and innovation to create the nursing workforce of the future. In this article, we briefly discuss today’s challenges and the pandemic disruption and subsequent call for innovation. We offer evidence to support the path forward and examples of how to layer technology into innovative teaching and learning.
The Significance of the NP Preceptorship Shortage
Authors: McInnis Angie , Schlemmer Tanya , Chapman Barbara
Published: July 2021

Nurse practitioner (NP) students are often unaware of the difficulties they will face finding preceptors. Many graduate programs lack a network of preceptors, forcing students to reach out to anyone who will agree to precept. Nursing and other healthcare provider programs often compete for the same clinical sites and preceptors. In this article, we offer a comparison of clinical education models by provider and briefly discuss current concerns that impact NP students, such as opposition for practice autonomy and the COVID-19 pandemic, as they seek to complete the required clinical hours to graduate. Also included is general information about the NP preceptor, with a description of requirements and responsibilities of the role. Our discussion suggests several philosophical dilemmas of NP preceptorship, including pay for preceptors, and considers expectations for the future.
Rationing Evidence-Based Nursing Practice: Considering a Resource-Based Approach
Authors: Klimek Yingling Jennifer
Published: July 2021

In 2020, the COVID-19 pandemic impacted the United States and the global healthcare system. The lack of agency and national stockpiles of personal protection equipment led to rationing and alteration in best infection prevention practices. The lack of resources forced nurses to make decisions based on resources rather than evidence. This article offers a brief review of the tenants of evidence-based practice, and discusses EBP during the COVID-19 pandemic. Presented is information about the concepts important to a resource-based view, and a potential modification of an EBP model that adds the perspective of resource-based practice to include the actual availability of resources to inform clinical decision-making by nurses and other providers.
A dual Bregman proximal gradient method for relatively-strongly convex optimization
Authors: Liu Jin-Zan , Liu Xin-Wei
Published: July 2021

We consider a convex composite minimization problem, whose objective is the sum of a relatively-strongly convex function and a closed proper convex function. A dual Bregman proximal gradient method is proposed for solving this problem and is shown that the convergence rate of the primal sequence is \begin{document}$ O(\frac{1}{k}) $\end{document}. Moreover, based on the acceleration scheme, we prove that the convergence rate of the primal sequence is \begin{document}$ O(\frac{1}{k^{\gamma}}) $\end{document}, where \begin{document}$ \gamma\in[1,2] $\end{document} is determined by the triangle scaling property of the Bregman distance.