bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of the increasing use of technology upon marketing in the 21st century
Authors: Dana Carmen Zechia
Published: November 2021

Technology is changing the face of the world today. It is one of the most catalysts for today’s changes in how marketing is done. However, consumers have great and collective power to ‘dictate’ what companies do. We can highlight several of the more apparent impacts of technology on markets and the organizations competing in these markets. While change is challenging, it is also exciting. Organizations that are market-driven and learn how to leverage technologies and other competencies can anticipate promising opportunities for growth and performance.
Preliminary research on testing physical general training and specific of the naval pentathlon team from the Naval Academy "Mircea cel Batran" – seamenship sample
Authors: A Abramiuc
Published: November 2021

As an expression of the degree of development of every driving skill, in this study I applied for objective assessment on physical general training, seven parameters in the disciplines: athletics and swimming, disciplines practiced by military athletes prior to the selection of the national pentathlon team. Tests were applied during experimental stage 1 twice, and the results obtained by the subjects of the two groups were statistically processed. Testing specific physical training included: A. Testing general psychomotor capacity; B. Testing of sensory skills; C. Testing of intellectual skills - concentrated attention, figures – ACC.
Delivery of Gaseous Nitric Oxide to the Extracorporeal Circulation Circuit: Experimental and Clinical Data: a review
Authors: Pichugin Vladimir V. , Bautin A. E. , Domnin S. E. , Ryazanov M. V. , Sandalkin E. V.
Published: November 2021

Introduction. Usually, gaseous nitric oxide (NO) is supplied to the patient by inhalation, adding to the inhaled gas mixture during spontaneous breathing, or supplying it to the inspiratory part of the ventilator. It is believed that the main point of its action is the pulmonary vasculature, where it exhibits an expanding effect, thus improving the oxygenation of arterial blood and reducing the pulmonary artery pressure. However, data from recent experimental clinical studies suggest that the addition of NO directly to the gas mixture supplied to the oxygenator makes it possible to systemically deliver NO into the bloodstream and, thereby, reduce the inflammatory response of the whole body caused by the extracorporeal circuit (cardiopulmonary bypass [CPB] or extracorporeal membrane oxygenation [ECMO]). Materials and methods. The search for publications was carried out in electronic databases PubMed, EMBASE. The last search term was December 30, 2020. The search term included the following words: “nitric oxide” and “artificial circulation” or “ECMO”. Only experimental and clinical randomized controlled blinded studies were selected for inclusion in the review. Results. The article analyzes data from recent studies related to the delivery of gaseous NO to the extracorporeal circuit, among which the issues of both NO delivery into the cardiopulmonary bypass line and the systemic and organ effects of nitric oxide delivered to the circuit are considered. The cardioprotective and anti-inflammatory effects of NO supplied to the extracorporeal circulation are considered in detail, as well as its effect on the lungs and kidneys. Conclusions. Further new randomized trials are needed to determine the place of the technology for supplying gaseous nitric oxide to the line of heart-lung machines or ECMO in modern cardiac surgery.
Modern approaches to the diagnostics, treatment and prevention of severe community-acquired pneumonia in adults: a review
Authors: Avdeev S. N. , Belotserkovskiy Boris Z. , Dehnich A. V. , Zaytsev A. A. , Kozlov R. S. , Protsenko D. N. , Ratchina S. A. , Sinopalnikov A. I. , Yakovlev S. V. , Yaroshetskiy A. I.
Published: November 2021

The article provides an overview of literature on severe community-acquired pneumonia (CAP) and the most recent data on the epidemiology and etiology of CAP, and describes the antibiotic susceptibility of Streptococcus pneumoniae — the leading causative agent of CAP. The article discusses demonstrative diagnostic data and emphasizes the need to determine as early as possible the oxygen saturation of arterial blood using a pulse oximeter, as well as to dynamically measure the concentration of inflammatory markers in blood and carry out a comprehensive microbiological examination. The authors argue for the advantages of computed tomography over conventional x-ray examination and point out the usefulness of ultrasound to diagnose and dynamically assess the condition of lung tissue in the course of treatment. The article also provides up-to-date recommendations for the differential antibiotic treatment of severe CAP patients based on the existence of risk factors making them susceptible to the infection with certain microorganisms, and suggests etiotropic therapy regimens for cases where the causative agent has been identified. It also emphasizes the need for a timely prescription of combined antibiotic therapy with intravenous administration, suggesting the possibility of de-escalation based on microbiological data. A substantial portion of the overview focuses on the respiratory therapy for CAP, outlining a graded algorithm for the treatment of acute respiratory failure based on stage, and describing in detail the most effective and safe invasive and non-invasive respiratory support strategies. The proposed adjuvant therapies include glucocorticosteroids if it is impossible to stabilize hemodynamics by means of adequate hydration and vasopressor support, as well as parenteral anticoagulants to prevent thromboembolic complications. Pneumococcal and influenza vaccines are suggested as CAP prevention strategies for high-risk patients. The publication seeks to highlight the most critical aspects of the draft of the updated clinical recommendations for CAP and encourage their wide discussion across the community of Russian intensive care anesthesiologists and intensivists.
Examining the Discrimination of Binary Scored Test Items with ROC Analysis
Authors: ÇÜM Sait
Published: November 2021

In this study, it was claimed that ROC analysis, which is used to determine to what extent medical diagnosis tests can be differentiated between patients and non-patients, can also be used to examine the discrimination of binary scored items in cognitive tests. In order to obtain various evidence for this claim, the 2x2 contingency table used in the ROC analysis was adapted in accordance with the logic of item discrimination. It was suggested in the article that the areas under the ROC curves (AUC) obtained by using the sensitivity and specificity values calculated with the adapted contingency table can be considered as a measure of item discrimination. The results of the statistical analyses made on the simulation data showed that the AUC values were positively and highly correlated with the D, 𝑟bis and a parameter values of the items, and the AUC values from different sized samples were consistent. Additionally, ROC analysis was more stable against range narrowing than other methods. In this respect, it was concluded that very large groups were not needed to examine item discrimination with the proposed method.
Strategy for the Implementation of Credit Cooperation Management System Based Online Application to Increase the Income of Cooperative and Members
Authors: Sudjatmoko Agung , Rahmana Febrizal , Farmania Aini
Published: November 2021

The application of business management systems and cooperative organizations faces the challenges of the development of business dynamics due to the development of science and technology. The use of information technology in all business actors is a form of adaptation to anticipate business development that aims to increase competitiveness and win competition. Cooperative is a business that still has obstacles in optimizing the use of IT to manage businesses in providing services to members. Therefore, through the use of the cooperative organization's business identification methods, the analysis of the guidelines for the use of cooperative online systems, training and outreach, and evaluating the implementation of activities. In this case, the community service activities can provide results that have an impact on optimizing the online cooperative system in improving services and incomes of members and cooperatives.
Virtual Face to Face Meeting for Non-Technical Personnel
Authors: Budijono Santoso , Tanutama Lukas
Published: November 2021

Covid-19 has impacted profoundly the business environment. Information and Communication Technology (ICT) becomes not only the major platform but also sustains the existence and running most business. Retail business becomes more dependent on technology. Small Business Enterprises (SME) have to jump and become savvy in ICT. The SME supply chain and marketing environment are moving toward ICT based platforms. On the other side the penetration of social media tool especially smartphone is widely spread. It can be safely assumed that every job holder whether entrepreneur, employee, or professionals or craftspeople is familiar with smartphones. The gap that must be bridged is using smartphone for business purposes. One of the business requirements that are not easy to replace is face to face communications. As Internet is ubiquitous and smartphones can easily access the Internet, there are numerous application that can resides both in computers and smartphones. The application that is closely similar to face to face meeting is known as Video Conference call. With this application it is possible to perform business briefing any time and anywhere provided there is Internet access. As business communication is not limited to technically savvy parties, a supportive system must be selected and introduced to them. We select Zoom as the application and develop a simple training syllabus. The syllabus has been implemented to a retail chain.
Penulisan Esai Akademik dan Strategi untuk Lolos Konferensi Internasional
Authors: Nadelia Febrina , Indrawati Desi , Perdani Yella Dezas
Published: November 2021

Academic writing activities for students are to convey ideas, arguments, and be involved in scientific activities. In academic writing, it is always classified by evidence-based arguments, correct word choice, logic, and structure. Although it is sometimes considered wordy, proper academic writing is one that informs, analyzes, and engages readers directly and critically. Moreover, knowing the stages of academic writing and how to write correctly is also needed in writing essays and motivation letters to pass international conferences selection. Every international conference usually demands conference applicants to prepare their essays and motivation letters comprehensively. Therefore, if students are interested in participating in international conferences, they should try to make interesting essays and motivation letters, both in terms of titles, innovations, and solutions that give new colors in the fields they participate. The purpose of this service through the webinar on academic essay writing and strategies for passing the international conference selection is to provide education and knowledge of writing and scientific thinking skills for students and to motivate and expand their insights to participate actively in international conferences by preparing their essays and motivation letters as the requirements for participating in international conferences. Participants who took part in this webinar were 61 students from Bina Nusantara University Bandung Campus, Pasundan University, UNIBI Bandung, and STIEPAR YAPARI Bandung. There are several series of events held in this webinar. The results of this service showed optimism and positive responses from the participants to make proper and structured writing and encourage their urge to participate actively in international conferences with the initial stages of writing essays and motivation letters.
Roteamento de Veículo Guiado Autonomamente para armazéns inteligentes
Authors: Lima Wesley Marques , Rocha Honovan Paz
Published: November 2021

A área de logı́stica, presente em grande parte da indústria, comércio e serviços, é uma das que mais necessitam de investimento em tecnologia para otimização de recursos, de maneira que o produto ou serviço final da empresa se mantenha no mercado de maneira estável e mais competitiva. Com o intuito de aperfeiçoar a logı́stica vários trabalhos da literatura trazem estudos com Veı́culos Guiados Autonomamente (Automated Guided Vehicles-AGVs) com a intenção de tornar autônomo o transporte interno de mercadorias e consequentemente mais eficiente. Um dos desafios dos AGVs é a roteirização, que é a busca por caminhos mı́nimos entre um estado inicial e os objetivos. Com o objetivo de estudar e solucionar este problema, o presente trabalho busca modelar computacionalmente um projeto real de armazém inteligente e implementa 3 algoritmos, Busca de Custo Uniforme, A* e Colônia de formigas, que são aplicados ao modelo representado através de um grafo. Eles são implementados para várias instâncias do problema, e em seguida seus resultados são avaliados e comparados.
Estrategias terapéuticas para Helicobacter pylori en Colombia
Authors: Zuluaga Arbelaez Nicolás , Sierra-Vargas Elsy Cristina , Guevara-Casallas Luis Gonzalo , Pérez-Viana Santiago
Published: November 2021

El amplio espectro de enfermedades causadas por la infección Helicobacter pylori obliga a un diagnóstico oportuno y dar un tratamiento altamente eficaz, reduciendo el riesgo de morbilidad y aumentando la probabilidad de erradicación. Son varias las terapias que tienen respaldo en la literatura, por lo que se deben conocer sus ventajas y limitaciones, incluyendo las resistencias bacterianas locales y seleccionar la mejor opción. Este artículo revisa los esquemas de tratamiento más utilizados y ofrece pautas para el manejo y seguimiento del paciente con infección por Helicobacter pylori en Colombia.
Disección coronaria espontánea
Authors: Lopera-Mejía Laura , Velásquez-Ospina Juanita , Franco-Zapata Alejandra , Zuluaga-Martínez Melisa , Duque Ramírez Mauricio
Published: November 2021

La disección coronaria espontánea es la separación de capas de la pared de una arteria coronaria epicárdica secundaria a hemorragia intramural, con o sin desgarro de la íntima, no asociada con aterosclerosis, traumatismo o iatrogenia. Esta enfermedad ha emergido como causa de síndrome coronario agudo e infarto agudo de miocardio en personas jóvenes, principalmente mujeres, cuya prevalencia de factores de riesgo cardiovasculares es menor en comparación con el síndrome coronario agudo por aterosclerosis. Su diagnóstico se hace con síntomas clínicos, exclusión de causas secundarias, arteriografía coronaria y a veces, con la ayuda de imágenes intra o extravasculares. En la mayoría de los casos el manejo es conservador, con algunas excepciones en donde se requiere intervención percutánea o quirúrgica. Se presenta el caso de un paciente masculino de mediana edad con disección coronaria espontánea, quien se presentó con un infarto agudo de miocardio con elevación del segmento ST.
Lembitu: A medieval warlord in Estonian culture
Authors:   University of Tartu, Selart Anti ,   St. Petersburg State University
Published: November 2021

The 13th century was undoubtedly a period of upheaval in Baltic history. From the traditional «Estonian» point of view, between 1208 and 1227 ancient Estonians heroically defended their political and personal freedom and native religion, but unfortunately they had to surrender to German invaders and the Catholic Church. This interpretation was adopted by the Estonian audience by the end of the 19th century. However, there were not many individual historical heroes to find in medieval history who could fit the national narrative. The 13th-century sources mention very few Estonians by their names. There is one exception: Lembitu, the leader of Sakala province. In 1217 he was killed in battle; his head was cut off and taken away by crusaders. Numerous artistic presentations popularised the person of Lembitu in the 19th and 20th century and shaped the public image of Lembitu as a king-like leader of the resistance in the name of freedom and independence. At the same time, in the early 2000s parallelly an ironic or critical attitude towards traditional presentations of the medieval warlord developed. A new turn in the presentations of Lembitu in Estonian media happened in the 2010s. The topic then became connected to the question of the fate of the skull of the medieval warlord. In Estonia in the 1960s, a report began to circulate that somewhere in Poland the head of Lembitu still existed. The Estonian Ministry of Culture initiated in 2014 contact between the Estonian and Polish ministries of culture, which resulted in some investigations in Polish museums with the aim of locating the artefact. The initiative was renewed in 2017, and in 2018–2019 the Estonian Ministry of Culture funded the research of the sources of Estonian history in Poland. Although the aim of the research in Poland was defined broadly and had real scholarly results, for the media and public audience it was definitely the project «searching for the skull of Lembitu». The public need for a historical hero, local patriotism combined with tourism marketing, and at least during the last decades the playful handling of history or historical stereotypes shape in combination the presentations of Lembitu in Estonian media and culture today.
Reserve Hortyca and its place in historical memory
Authors:   Institute of History of Ukraine, National Academy of Sciences of Ukraine, Kasianov Georgiy Vladimirovich , Tairova-Yakovleva Tatiana Gennadyevna ,   St. Petersburg State University
Published: November 2021

This article is dedicated to the place of the Hortyca reserve in the Cossack myth and the historical memory of Ukraine. The Cossack myth at different stages of its formation, in its post-Soviet-populist version, was successfully integrated into the state policy of memory of independent Ukraine. The article reveals the stages and the historical context of the creation of the Hortyca reserve, shows the lack of a historical base for the «reconstruction» of the Zaporizhisn Sich. Nevertheless, the Cossack movement and the Cossack theme gain an important place in the historical politics of the presidents. The Cossack movement also became participants and organizers of public commemorative actions associated with significant events in Cossack history. The events of the Maidan 2013–2014 added new colors to the Cossack myth. The use of the Hortyca complex for the formation of an artificial place of memory associated with the Zaporizhzhya Sich and the Cossacks is studies. It is shown that there was no historical or archaeological basis for the formation of the memorial on Bolshaya Hortyca. Nevertheless, since the time of N. Yavornitsky, a number of stages in the creation of such a place of memory can be traced. In particular, P. Shelest’s decisions on perpetuating the memory of the Zaporozhian Cossacks. In 1965 was made a decision to create a historical and cultural reserve «Hortyca». One of the key places is the grave of the ataman I. Sirko. The exhumation and further investigation of Sirko’s remains became the subject of a war of memory. Only in 2000, the skull of the legendary chieftain was buried. The reserve itself remained the subject of speculation and manipulation of the Cossack myth, since would not be based on either historical or archaeological data, but it was based on the idea of recreating a certain generalized image. As a result, the complex «Hortyca’s Sich» turned out to be a generalized image of Cossack fortifications with an attempt to reproduce the structure of all eight Cossack sections that existed in the 17th–18th centuries. The complex is actively used by reenactors and folklorists.
Formulation of gude bean flour (Cajanus cajan), with kratok bean (Phaseolus lunatus) and red bean (Phaseolus vulgaris) in making of functional snack bar
Authors: Widnyani Ida Ayu Putu Ary , Rabani RS I Gusti Agung Yogi
Published: November 2021

Snack bar is a snack that is consumed between meals. Snack bars are usually made from nuts, cereals, and dried fruit. Snack bars are made to meet nutritional intake and overcome hunger amid busy activities. Snack bar products made from local raw materials need to be developed considering the many sources of food that have functional benefits. Samples were tested for carbohydrate, protein, fat, moisture content, and ash content. The results obtained were then statistically analyzed using a completely randomized design analysis. The study used 7 treatments and 3 replications so that the researcher had 21 experimental units. The comparison treatment of gude bean flour with red beans and kratok beans on snack bar products has a carbohydrate content of 41.826 – 45.310%, protein 13,234 – 33,869%, fat 10.046 – 10.796%, ash content 0.704 – 1.343%, and water content 6.344 – 6.819%.
Topical Probiotics for Women’s Urogenital Health: Selection of an Oil-based Carrier
Authors:   Canadian Centre for Human Microbiome and Probiotics, Lawson Health Research Institute, London, Ontario, Canada, Puebla-Barragan Scarlett ,   Departments of Microbiology and Immunology, and Surgery, Western University, London, Ontario, Canada, Lamb Britney ,   Canadian Centre for Human Microbiome and Probiotics, Lawson Health Research Institute, London, Ontario, Canada,   Departments of Microbiology and Immunology, and Surgery, Western University, London, Ontario, Canada, Jafelice Serenah ,   Canadian Centre for Human Microbiome and Probiotics, Lawson Health Research Institute, London, Ontario, Canada,   Departments of Microbiology and Immunology, and Surgery, Western University, London, Ontario, Canada, Reid Gregor ,   Canadian Centre for Human Microbiome and Probiotics, Lawson Health Research Institute, London, Ontario, Canada,   Departments of Microbiology and Immunology, and Surgery, Western University, London, Ontario, Canada
Published: November 2021

Vaginal care products are widely used by women to relieve discomfort such as pain, itching and malodour, all of which are commonly caused by conditions resulting from microbiota dysbiosis. Previous studies showed that probiotic strains Lacticaseibacillus (formerly Lactobacillus) rhamnosus GR-1 (LGR-1) and Limosilactobacillus (formerly Lactobacillus) reuteri RC-14 (LRC-14), can aid in restoring homeostasis in the vaginal microbiome when taken orally. A topical product containing these strains could be of value for reducing malodour and improving quality of life. However, the formulation of such a product is a challenge, given that its ingredients must maintain shelf-life viability by excluding moisture. Here, we tested petroleum jelly, mineral oil, coconut oil, and olive oil for how well they maintained the viability of freeze-dried probiotic strains over a six-month timeframe. None of the oils caused excessive loss of bacterial viability, with petroleum jelly and coconut oil showing the most promise. Based on existing knowledge of these oils on the female genitalia, coconut oil and petroleum jelly could be suitable probiotic carriers for clinical testing.
Obstacle Detection Based on 3D Lidar Euclidean Clustering
Authors: Jinming Chen
Published: November 2021

Environment perception is the basis of unmanned driving and obstacle detection is an important research area of environment perception technology. In order to quickly and accurately identify the obstacles in the direction of vehicle travel and obtain their location information, combined with the PCL (Point Cloud Library) function module, this paper designed a euclidean distance based Point Cloud clustering obstacle detection algorithm. Environmental information was obtained by 3D lidar, and ROI extraction, voxel filtering sampling, outlier point filtering, ground point cloud segmentation, Euclide clustering and other processing were carried out to achieve a complete PCL based 3D point cloud obstacle detection method. The experimental results show that the vehicle can effectively identify the obstacles in the area and obtain their location information.
Learner’s perception of task difficulties in technology-mediated task-based language teaching
Authors: Butarbutar Ranta
Published: November 2021

The perception of learners can be used for evaluating task-based language teaching development. However, during the technology-mediated task-based language teaching (TBLT), learners faced a few difficulties. Thus, this study aimed to investigate learners’ perceptions of task difficulties in technology-mediated (TBLT). To collect data, the study used a quantitative design with an open-ended questionnaire, and, involved two hundred learners as participants who came from different departments at the university. The results strongly confirmed that incorporating technology into TBLT leads learners to face some difficulties in (1) understanding the meaning of the task, (2) practical instruction in doing tasks, (3) applying new technology to explore profound tasks further, (4) lack of direct lecturer feedback on student tasks, (5) performance assessment, (6) addressing learners’ needs, (7) goal orientation, (8) digital literacy, building knowledge, intellectual, and behavior, and (9) school and curriculum rules. Furthermore, the study preferred some strategies to solve learners' difficulties in TBLT, such as managing teaching materials to become easier and more interesting, referring technology integration to learners’ ability, implementing bring your own device (BYOD), improving classroom assessment, teachers broadening technology-mediated, task-based learning internships, and facilitating learners with compatible technology tools and stable internet connection.
Addressing English language needs of Economic Development students in Indonesian context
Authors: Dewi Mercya Christ Sita , Indriani Lilia
Published: November 2021

The heart of the study is English for Economics purposes as a branch of English for Specific Purposes (ESP). This study is dedicated to addressing the immediate needs of economics students in English language courses. By employing an explanatory survey method, researchers distributed a self-administrated survey and interviewed five first-year students majoring in Economic Development in one of the state universities in Indonesia. In this study, the researchers attempted to analyze Economic Development students’ target situation, present situation, and learning situation in English courses to prepare them to face global competition. The results revealed that most students admitted that English is essential for their future careers. Thus, they expected English courses should include materials related to their discipline and emphasize more authentic activities. Following the discussion, this need analysis can be a consideration in designing English learning materials for economics students.
Investigasi Perancangan Simulasi Antena MIMO 64 Elemen untuk Aplikasi 5G
Authors: Rahayu Yusnita , MZ Saftriansyah
Published: November 2021

Teknologi 5G merupakan teknologi yang digunakan untuk memenuhi kebutuhan layanan berbasis nirkabel berkecepatan tinggi. Frekuensi 28 GHz merupakan salah satu rentang frekuensi yang direkomendasikan oleh Federal Communications Commission (FCC) dalam pengembangan teknologi 5G. Dalam perancangan ini, antena menggunakan patch berbentuk rectangular yang dirancang agar antena dapat bekerja pada frekuensi 28 GHz. Rancangan antena 5G ini menggunakan pencatuan microstrip line dan Teknologi Multiple Input Multiple Output (MIMO). MIMO adalah salah satu teknologi yang mendukung 5G. Antena MIMO ini dirancang menggunakan bahan substrat RT-Duroid 5880 untuk menghasilkan nilai S11 sebesar -45,185 dB dengan gain sebesar 24,22 dBi, dan bandwidth sebesar 840 MHz.
Telemental Health through a Racial Justice and Health Equity Lens
Authors: Carrington Scune , Driskell Jeff
Published: November 2021

Telehealth has become an increasingly popular method of delivery of
health-related services. Under the umbrella of telehealth lies
telemental health (TMH). Although this type of modality has been around
for quite some time, it was not until the arrival of Covid-19 during
2020-2021 that the United States healthcare system began to fully
accept, embrace, and implement TMH. Due to public health restrictions
related to Covid-19, in person therapy and other social services were
prohibited (or restricted) thus relying on TMH. This article discusses
the link between a racial justice lens, minority stress theory, health
equity and identifies barriers/challenges in telemental health that do
not reflect equity in health for racial minorities including Black,
Indigenous, Hispanic, and Latinx communities, and all communities of
color.
A European pharmacotherapeutic agent Roflumilast exploring integrated preclinical and clinical evidences for SARS CoV-2 mediated inflammation to organ damage
Authors: Singh yogendra , Fuloria Neeraj , Fuloria Shivkanya , Subramaniyan Vetriselvan , Almalki Waleed , Al-abbasi Fahad , Kazmi Imran , Rajput Sobhit , Gupta Gaurav
Published: November 2021

COVID-19 has spread globally, affecting almost 160 million individuals.
Elderly and pre-existing patients (such as diabetes, heart disease and
asthma), seems more susceptible to serious illness with COVID-19.
Roflumilast was licensed for usage in the European Union in July 2010 as
a phosphodiesterase-4 (PDE4) inhibitor. Roflumilast has been shown to
decrease bleomycin-induced lung fibrosis, lung hydroxyproline, right
heart thickning in animal prophylactic. The current study reviewed
existing data that the PDE-4 inhibitor protects not just renal tissues
but also other major organ systems after COVID-19 infection by
decreasing immune cell infiltration. These immune-balancing effects of
roflumilast were related with a decrease in oxidative and inflammatory
burden, caspase-3 suppression, and increased PKA/cAMP levels in renal
and other organ tissue.
Impaction caused by a Rare erupted peripheral compound Odontoma
Authors: marya anand , Venugopal Adith
Published: November 2021

Odontomas are common occurrences in the oral cavity and can be
classified as complex or compound. Erupted peripheral compound odontomas
are rare and are present in the extra-osseous soft tissues. In this case
the odontoma led to the impaction of permanent teeth for which removal
of the lesion was advised.
Emergency management plan for paediatric patients with tracheostomies during the COVID-19 pandemic
Authors: Petulla Beckie , Ho Emma , Sov Emma , Soma Marlene
Published: November 2021

Objectives: Paediatric patients living with tracheostomies are a
medically vulnerable group. During the COVID-19 pandemic, there may be
apprehension about their susceptibility to SARS-CoV-2 infection with
unknown consequences. Healthcare workers managing this cohort can be
anxious about viral transmission from respiratory secretions and
aerosols emerging from the open airway. Our objective is to share a
systematic approach to minimise incidental mismanagement, avoid
iatrogenic airway injury, reduce aerosolisation and decrease staff
exposure when treating these patients. Methods: A COVID-19 emergency
management plan was created for paediatric patients with tracheostomies
in the event of presentation with unknown, suspected or proven
SARS-CoV-2 infection. Three documents were developed: a generic
tracheostomy management plan detailing troubleshooting measures to
reduce air leak from around the tube; a personalised management plan
with customised recommendations; a guide for tracheostomy tube change
with emphasis on minimising aerosol production. Results: Our plan was
distributed to 31 patients (age range 11 months - 17 years) including 23
(74.2%) with uncuffed tubes and 9 (29%) on long term ventilation.
There have been 10 occasions in which the plan was utilised and
influenced care, including 4 situations where successful troubleshooting
avoided tube manipulation and 6 situations where an uncuffed tube was
safely replaced with a pre-selected cuffed tube to reduce air leak.
Conclusions: A structured approach to emergency presentations during the
COVID-19 pandemic may safeguard paediatric patients from unnecessary
manipulation of their tracheostomy tube and airway trauma, as well as
provide guidance to minimise viral exposure and allow provision of
expeditious care.
Metformin: an old drug with potential therapeutic function in antitumor
Authors: mu wei , Jiang Yunyun , Qu Falin
Published: November 2021

Metformin is one of the first-line and widely-used drugs in patients
with T2DM due to its safety profile, clinical efficacy and cheap cost.
It is clearly that metformin has benefits on lowering hyperglycemia and
diabetes-related complications in clinical use. The classic effect of
metformin is to reduce hepatic glucose production by inhibiting
gluconeogenesis in liver and increase glucose utilization in peripheral
tissues. Metformin targets mitochondrial respiratory chain complex I to
specifically reduce reactive oxygen species generation to protect cells
against oxidative stress-induced cell apoptosis. AMPK complex is a key
factor in the action of metformin; however it is inconclusive that
whether metformin activate AMPK directly or indirectly. In addition,
more and more studies showed that metformin act on gut microbiota to
exert anti-hyperglycemia effect. Emerging evidence showed that metformin
has off-label function on antitumor therapy; however the underlying
mechanism of this property of metformin still remains elusive. Taken
together, in this review we provide a new perspective on metformin and
repurpose its novel and promising application in antitumor therapy.
PENGARUH KORUPSI, KUALITAS PEMBANGUNAN MANUSIA DAN PENANAMAN MODAL ASING (FDI) TERHADAP KEMISKINAN DI ASEAN
Authors: Gumala Fika , Anis Ali
Published: November 2021

This study aims to find out how the effects of corruption, the quality of human development and foreign investment on poverty in ASEAN. The data used is secondary data in the form of a panel of data from 2012 to 2016, with data collection techniques are library studies obtained from relevant institutions and agencies. The variables used are Corruption, Quality of Human Development, Foreign Investment and Poverty. The research methods used are: (1) Pooled Analysis (2) Determination Coefficient (3) T Test (4) Test F. The results of the study show that corruption has a significant positive effect on poverty. This means that increasing corruption tends to lead to increasing poverty. While the quality of human development has a significant negative effect on poverty. That is, the increasing quality of human development tends to cause more poverty. Meanwhile, foreign investment has no influence on poverty. This means that the increasing number of foreign investments cannot reduce poverty.
PENGARUH KORUPSI, DEMOKRASI DAN POLITIK TERHADAP KEMISKINAN DI DELAPAN NEGARA ASEAN DENGAN PERTUMBUHAN EKONOMI SEBAGAI VARIABEL MODERASI
Authors: Yolanda Yolanda
Published: November 2021

This study aims the influence of corruption, democracy and politics on poverty in ASEAN countries with economic growth as a moderating variable. The method used is using the panel regression model. This data uses a combination method between time series data from 2013 - 2016 and a cross section consisting of 8 countries. Data obtained from World Bank annual reports, Transparency International and Freedom House. The results of this study indicate that (1) Corruption Perception Index (CPI) has a significant and negative effect on poverty, meaning that if the CPI increases then poverty will decrease (2) Democracy has no significant and negative effect on poverty. This means that if democracy increases, poverty will decrease (3) Politics has a significant and negative effect on poverty, meaning that if politics increases, poverty will decrease (4) Economic growth has a significant and positive effect on poverty, meaning if economic growth increases then poverty will decline (3) Economic growth unable to moderate the relationship between corruption, democracy and politics towards poverty in 8 ASEAN countries. Economic growth as an interaction variable is a predictor variable (Predictor Moderate Variable), which means that economic growth is only an independent variable.
ANALISIS HUBUNGAN HARGA EMAS, HARGA SAHAM, NILAI TUKAR DAN SUKU BUNGA DI INDONESIA: PENDEKATAN GRANGER CAUSALITY DAN VECTOR ERROR CORRECTION MODEL (VECM)
Authors: Sriwulan Junita , Ariusni Ariusni
Published: November 2021

This studi aim to indentify and analyze the realtionship between Gold Price, Stock Price, Exchange rate and Interest rate in Indonesia. The type of this research is associative descriptive research. Where the data used is monthly data of time series from January 2014 to December 2019 obtained from Bank of Indonesia (BI) and hargaemas.org. Analysis model uses Granger Block Causality, Vector Error Correction Model (VECM) to see  interaction the long and short term between of variabel, Impluse Response Function (IRF) and Forecast Error Variance Decomposition (FEVD) in looking at the response of variability to the variables to the variables associated with those shown by other endogenous variables. The finding of this study indicate that:(1) There is a one way causality relationship between interest rate and gold price, where only  interest rate affects gold price. (2) In the short run, Shock of stock price, exchange rate and interest rate do not contribute to the variability of gold price in Indonesia, but shock of  exchange rate is only to variability response of gold price on long run. (3) Shock of gold price, exchange rate and interest rate do not contribute to the variability  of stock price in short term but variability of stock price is only based on long term gold price shock. (4) Exchange rate variability is contribute by stock price in the short and long term. But, in the long run shock interest rate also to the varibility of stock price. (5) Variability of interest rate is only contibuted by gold price in the short and long term in Indonesia.
PENGARUH TEKNOLOGI INFORMASI DAN KOMUNIKASI TERHADAP PASAR TENAGA KERJA DAN PERTUMBUHAN EKONOMI DI INDONESIA
Authors: Putri Rahmadani , Idris Idris
Published: November 2021

Abstract : This study discusses the study and analysis of Information and Communication Technology (ICT) on the Labor and Economic Markets in Indonesia. The data used in this study are panel secondary data from 2012 to 2018 with a sample of 34 provinces in Indonesia. Data obtained from related institutions and then analyzed using the simultaneous equation model (simultaneous equation regression model) with the Indirect Least Square (ILS) method to calculate indirect parameters and calculated using the first with the application of the OLS model through the selection of the CEM, FEM and REM model then continued with classic trials. Partial research results show, Information and communication technology has a significant influence on the Labor Market in Indonesia. Furthermore, simultaneous, Information and Communication Technology and Labor Market have a significant influence on the economic conversation in Indonesia Indonesia. However, partially, Information and Communication Technology has a negative influence on the acceleration of the Economy in Indonesia. Based on the results of this research, the steps in the progress of Information and Communication Technology have become one of the studies for governments that need help, in order to increase insight, use, use, and match for policy makers in developing countries specifically Indonesia so that it can be an appropriate intervention to influence per capita economic growth.Keywords: Information and Communication Technology, Labor, Economic Communication, Solow Model and Simultaneous Equation Model
THE USE OF DISCORD APPLICATION IN VIRTUAL ENGLISH LEARNING: AN INVESTIGATION ON STUDENTS’ PERCEPTIONS
Authors: Jannah Evi Isfiatul , Hentasmaka Daning
Published: November 2021

Discord application, a voice and text chat platform usually used for games, social, class, or business groups, started to be used as one of the alternative media in virtual learning. A deeper investigation was conducted to get more information about students’ perception of virtual learning by using Discord application. This study implemented a qualitative research design, especially a case study. The data were collected from tertiary education students who were experienced in virtual English learning by using Discord by distributing an online questionnaire and doing interviews. Based on the results of data analysis, it was found that 89.72% of the students positively perceived the use of Discord application in virtual English learning. Some advantages of virtual learning by using Discord application found in the study were elaborated.
TECHNIQUES IN CONDUCTING ENGLISH READING SKILLS TEST PERFORMED BY INDONESIAN TEACHERS ON ASSESSMENT OF LOCAL EDUCATION STANDARD 2021
Authors: Mayasari Adhe Puspita , Susanti Ani
Published: November 2021

One of the ways to measure the students' English reading comprehension skills is through testing. Despite its significant value, students frequently construct bad tests without considering the main rules in doing English reading comprehension tests. This research concerns to study of techniques in testing English comprehension reading skills performed by teachers in Indonesia on Assessment of Local Education Standard in the year 2021. Assessment of Local Education Standard abbreviated as ASPD in a provincial- standardized test to maintain the quality of learning. Four EFL teachers in Indonesia were chosen based on their teaching experience in high schools. The researcher used document observation and in depth- interview techniques to collect data which were transformed into observation notes and interview transcription. The data were then analyzed qualitatively. Findings from this study shown that there are three main themes regarding the most used techniques performed by the teachers, first, students must be able to analyze the bloom taxonomy theory, second, students must be able to identify the scope of material, and third determining the keywords of the question. From understanding and doing those three themes, teachers believe that these techniques could help and improve student's ability in facing English reading comprehension tests.
An Online Participatory Observation: The Online Depression Community's Discussion on Depression Treatment
Authors: Wu Hsinzhu
Published: November 2021

This article uses the online participatory observation method to analyze more than 2,000 posts of the "Sunshine Project Psychological Mutual Assistance Forum" in Mainland China. The research observed the discussion of depression in the online patient community in anonymous forums, including the popularization of medical knowledge about diseases, self-disclosure of patient diagnosis and treatment experience, patient interaction, and patient discussions on controversial issues and rumors of the disease. The results of the study show that the online community of depression patients is both a "web of information" and a "web of mutual help." The patient's health information acquisition mode has changed from vertical reception to horizontal interconnection, which not only enhances patients' scientific understanding of the disease but also allows them to increase their sense of psychological security in their interpersonal interactions. In this new type of risk communication mode, how to establish a new fact-checking mechanism and establish ordinary people's trust in scientific and medical knowledge is a new challenge.
Entrevista a Analía Fernández Rojo. Colecciones bibliográficas especiales: el Catálogo Nacional Unificado de la Biblioteca Nacional “Mariano Moreno”
Authors: Paladino Ángela , Villalba Micaela , Miguel Matías
Published: November 2021

Entrevista a Analía Fernández Rojo. Colecciones bibliográficas especiales: el Catálogo Nacional Unificado de la Biblioteca Nacional “Mariano Moreno”
Нераспространение боевых ракет: правовой аспект
Authors: Тузмухамедов Б. Р.
Published: November 2021

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Бекяшев Камиль Абдулович, Верещетин Владлен Степанович, Игнатенко Геннадий Владимирович, Лукашук Игорь Иванович, Старушенко Глеб Борисович, Тункин Григорий Иванович
Authors: Редакционная статья
Published: November 2021

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Emergency Distance Learning in Austria during COVID-19: Selected Findings and Implications
Authors: Pelikan Elisabeth , Hager Katharina , Holzer Julia , Korlat Selma , Spiel Christiane , Schober Barbara , Lüftenegger Marko
Published: November 2021

Highlights:
(1) Adequate preparation (e.g., providing technical equipment, didactical adaptation of teaching materials, fostering digital literacy in students …) is needed for distance learning to succeed.(2) Disadvantaged students need special support to avert a widening of the educational gap between students from different social backgrounds and with different learning abilities.(3) Distance and online learning should be designed to address the satisfaction of basic psychological needs to promote student well-being and positive learning outcomes.
FOOD SUPPORT FOR THE ANDALAS UNIVERSITY STUDENTS DURING THE FIRST LOCKDOWN DUE TO THE COVID-19 PANDEMIC
Authors: Wellyalina Wellyalina , Hasbulla Hasbullah , Refdi Cesar Welya , Azrifirwan Azrifirwan , Arlius Feri
Published: November 2021

Background:  Distributing Food Supplies for andalas university students that wander in Padang who are affected by the Covid-19 Pandemic is essential.  Methodology: The distribution of basic food packages consisting of rice, eggs, cooking oil, milk and instant noodles has been carried out in 2 stages. This package can feed students for 1 week and help them to survive this difficult time. This program was directly supervised by the Dean of the Faculty of Agricultural Technology, Andalas University and implemented jointly with all members of the Faculty of Agricultural Technology, Andalas University. Conclusion: This activity can increase solidarity with the care of others affected by Covid-19 and also encourage understanding and interest in community empowerment, especially in tackling the spread of coronavirus
DISTRIBUTION OF HAND SOAP WITH THE AROMA OF EUCALYPTUS FOR PEOPLE AFFECTED BY THE COVID-19 PANDEMIC: A COMMUNITY SERVICE REPORT
Authors: Rasdiana Felga Zulfia , Novelina Novelina , Aisman Aisman , Hari Purnama Dini , Nazir Novizar
Published: November 2021

Background: The utilization of liquid hand soap is an alternative to prevent virus transmission in COVID 19 Pandemic. The production of aromatic hand soap and distribution to the public will be an effort to support the prevention of the spread of the corona virus. Methodology: Aromatic hand soap made from eucalyptus is produced and distributed to people in Padang City as an alternative product for people to maintain their personal hygiene. Conclusion: This eucalyptus-flavored handsoap has received a lot of positive feedback. This product can assist people in maintaining their personal hygiene. The public does not like the smell of eucalyptus oil in this hand soap product. The formulation of this product will need to be completed in the future.
The effect of meditation on depression, anxiety, and stress in university students
Authors:   Department of Nursing, Faculty of Health Sciences, Gümüşhane University, Gümüşhane, 29100, Turkey, Doğan Melike Demir , Polat Tuğçe ,   Sivas Numune Hospital, Sivas, 58040, Turkey, Yilmaz Muhammed Mücahit ,   İstanbul Başakşehir Şehir Hospital, İstanbul, 34494, Turkey
Published: November 2021

Purpose: The aim of this study is to determine the effect of meditation on depression, anxiety, and stress levels of university students. Design and Methods: In the study, the data were collected using personal information form and Depression, anxiety, and stress scale. The meditation group performed a 20-minute attention and awareness meditation once a week for 8 weeks. Findings: As a result of the statistical analysis, it was observed that there was no significant difference in the comparison of the anxiety, stress, and depression levels between two groups at the end of 8 weeks. Practice Implications: Consequently, it was determined that meditation was an ineffective approach for reducing the anxiety, stress, and depression levels.