bluuebunny/crossref_metadata_2025 huggingface dataset:
Considering Type 1 Diabetes as a Form of Accelerated Muscle Aging
Authors: Monaco Cynthia M. F. , Gingrich Molly A. , Hawke Thomas J.
Published: February 2019

Recent evidence reveals impairments to skeletal muscle health in adolescent/young adults with type 1 diabetes (T1D). Interestingly, the observed changes in T1D are not unlike aged muscle, particularly, the alterations to mitochondria. Thus, we put forth the novel hypothesis that T1D may be considered a condition of accelerated muscle aging and that, similar to aging, mitochondrial dysfunction is a primary contributor to this complication.
Quality Overprovision in Cable Television Markets
Authors: Crawford Gregory S. , Shcherbakov Oleksandr , Shum Matthew
Published: February 2019

We measure the welfare distortions from endogenous quality choice in imperfectly competitive markets. For US cable television markets between 1997–2006, prices are 33 percent to 74 percent higher and qualities 23 percent to 55 percent higher than socially optimal. Such quality overprovision contradicts classic results in the literature and our analysis shows that it results from the presence of competition from high-end satellite TV providers: without the competitive pressure from satellite companies, cable TV monopolists would instead engage in quality degradation. For welfare, quality overprovision implies cable customers would prefer smaller, lower-quality cable bundles at a lower price, amounting to a twofold increase in consumer surplus for the average consumer. (JEL L13, L15, L82)
Does Household Finance Matter? Small Financial Errors with Large Social Costs
Authors: Bhamra Harjoat S. , Uppal Raman
Published: February 2019

Households with familiarity biases tilt their portfolios toward a few risky assets. The resulting mean-variance loss from portfolio underdiversification is equivalent to only a modest reduction of about 1  percent per year in a household’s portfolio return. However, once we consider also the effect of familiarity biases on the asset- allocation and intertemporal consumption-savings decisions, the welfare loss is multiplied by a factor of four. In  general equilibrium, the suboptimal decisions of households distort also aggregate growth, amplifying further the overall social welfare loss. Our findings demonstrate that financial markets are not a mere sideshow to the real economy and that improving the financial decisions of households can lead to large benefits, not just for individual households, but also for society. (JEL D14, D91, E21, E44, G11, G41)
Familiarity Does Not Breed Contempt: Generosity, Discrimination, and Diversity in Delhi Schools
Authors: Rao Gautam
Published: February 2019

I exploit a natural experiment in Indian schools to study how being integrated with poor students affects the social behaviors and academic outcomes of rich students. Using administrative data, lab and field experiments to measure outcomes, I find that having poor classmates makes rich students (i) more prosocial, generous, and egalitarian; and (ii) less likely to discriminate against poor students, and more willing to socialize with them. These effects are driven by personal interactions between rich and poor students. In contrast, I find mixed but overall modest impacts on rich students’ academic achievement. (JEL C90, D31, I21, I24, O15, Z13)
Shear wave elastography for the diagnosis of small (≤2 cm) breast lesions: added value and factors associated with false results
Authors: Choi Hye Young , Seo Mirinae , Sohn Yu-Mee , Hwang Ji Hye , Song Eun Jee , Min Sun Young , Kang Hye Jin , Han Dong Yoon
Published: February 2019

Objective:

We compared the diagnostic performance of B-mode ultrasound, shear wave elastography (SWE), and combined B-mode ultrasound and SWE in small breast lesions (≤ 2 cm), and evaluated the factors associated with false SWE results.

Methods:

A total of 428 small breast lesions (≤ 2 cm) of 415 consecutive patients between August 2013 and February 2017 were included. The diagnostic performance of each set was evaluated using the area under the receiver operating characteristic curve (AUC) analysis. Histologic diagnosis was used as reference standard. Multivariate logistic regression analyses identified the factors associated with false SWE results.

Results:

Of 428 lesions, 142 (33.2%) were malignant and 286 (66.8%) were benign. The AUC of the combined modality was higher than that of B-mode ultrasound (0.792 vs 0.572, p < 0.001) and that of SWE was higher than that of B-mode ultrasound (0.718 vs 0.572, p < 0.001). Multivariate analysis showed that the smaller lesion size and in situ cancer were associated with false negative, and patient’s age, high-risk lesion, shorter distance from the skin or chest wall, and deeper breast thickness were associated with false positive (all p < 0.05).

Conclusions:

The addition of SWE to B-mode ultrasound could improve the diagnostic performance in ≤ 2 cm lesions. However, ultrasound lesion size, pathology, and lesion location are likely to affect the SWE value and result in false results.

Advances in knowledge:

Despite the diagnostic usefulness of SWE in small breast lesions (≤ 2 cm), ultrasound lesion size, pathology, and lesion location were associated with false results.
Gestão e saúde em simbiose
Authors: Tonelli Maria José , Wilner Adriana
Published: February 2019

Nessa primeira edição de 2019, queremos agradecer nossos autores e leitores pela frutífera parceria no ano que passou. Esperamos continuar com o apoio de todos no ciclo que se inicia.Ao celebrar a entrada de um novo ano, pedimos sempre “saúde para dar e vender”. Ésobre esse tema que versam os artigos do Caderno Especial desta edição. Não temos muitoa comemorar, infelizmente. A definição da Organização Mundial da Saúde (OMS) dizque “saúde é um estado de completo bem-estar físico, mental e social”. Parece que estamoslonge de alcançar o que essa definição nos propõe. Para que esse ideal seja alcançado, a saúde precisa cada vez mais da gestão, assim como vice-versa.
O déficit, a dívida e os custos dos serviços públicos
Authors: Sandroni Paulo
Published: February 2019

Serviços públicos não apresentam economias de escala: quanto mais se produz, mais aumentam os custos das unidades adicionais produzidas.
Epidiolex as adjunct therapy for treatment of refractory epilepsy: a comprehensive review with a focus on adverse effects
Authors: Sekar Krithiga , Pack Alison
Published: February 2019

Medically refractory epilepsy remains an area of intense clinical and scientific interest since a significant porportion of patients continue to suffer from debilitating seizures despite available therapies. In this setting, recent studies have focused on assessing the benefits of cannabidiol (CBD)-enriched cannabis, a plant based product without psychoactive properties which has been shown to decrease seizure frequency in animal models. More recently, several randomized controlled and open label trials have studied the effects of Epidiolex, a 99% pure oral CBD extract, on patients with refractory epilepsy. This in turn has led to the FDA approval of and more recently, to the Drug Enforcement Administration’s placement of Epidiolex into schedule V of the Controlled Substances Act (CSA). In this review, we summarize the major findings of several recent large-scale studies using this product with a focus on its adverse effects.
Characteristics of successful integrated family planning and maternal and child health services: Findings from a mixed-method, descriptive evaluation
Authors: Pfitzer Anne , Maly Christina , Tappis Hannah , Kabue Mark , Mackenzie Devon , Healy Sadie , Srivastava Vineet , Ndirangu Gathari
Published: February 2019

Background: Most postpartum women in low- and middle-income countries want to delay or avoid future pregnancies but are not using modern contraception. One promising strategy for increasing the use of postpartum family planning (PPFP) is integration with maternal, newborn and child health (MNCH) services. However, there is limited evidence on effective service integration strategies. We examine facilitators of and barriers to effective PPFP integration in MNCH services in Kenya and India.  

Methods: We conducted a cross-sectional, mixed-method study in two counties in Kenya and two states in India. Data collection included surveying 215 MNCH clients and surveying or interviewing 82 health care providers and managers in 15 health facilities across the four sites. We analyzed data from each country separately. First, we analyzed quantitative data to assess the extent to which PPFP was integrated within MNCH services at each facility. Then we analyzed qualitative data and synthesized findings from both data sources to identify characteristics of well and poorly integrated facilities.

Results: PPFP integration success varied by service delivery area, health facility, and country. Issues influencing the extent of integration included availability of physical space for PPFP services, health workforce composition and capacity, family planning commodities availability, duration and nature of support provided.

Conclusions: Although integration level varied between health facilities, factors enabling and hindering PPFP integration were similar in India and Kenya. Better measures are needed to verify whether services are integrated as prescribed by national policies.
Assessing drug target suitability using TargetMine
Authors: Chen Yi-An , Yogo Erika , Kurihara Naoko , Ohno Tomoshige , Higuchi Chihiro , Rokushima Masatomo , Mizuguchi Kenji
Published: February 2019

In selecting drug target candidates for pharmaceutical research, the linkage to disease and the tractability of the target are two important factors that can ultimately determine the drug efficacy. Several existing resources can provide gene-disease associations, but determining whether such a list of genes are attractive drug targets often requires further information gathering and analysis. In addition, few resources provide the information required to evaluate the tractability of a target. To address these issues, we have updated TargetMine, a data warehouse for assisting target prioritization, by integrating new data sources for gene-disease associations and enhancing functionalities for target assessment. As a data mining platform that integrates a variety of data sources, including protein structures and chemical compounds, TargetMine now offers a powerful and flexible interface for constructing queries to check genetic evidence, tractability and other relevant features for the candidate genes. We demonstrate these features by using several specific examples.
CONCEPTUAL VIEWS IN KYRGYZ LITERATURE ON THE ARTISTIC INTEGRATION OF HISTORICAL REALITY AND THE DEFINITION OF ITS ROLE
Authors: Эшмамбетова Нурай , Eshmambetova Nuray
Published: February 2019

The artistic integration of historical reality in literary works. In particular, the author identifies little-studied issues in the field of Kyrgyz literary criticism related to the definition of the current aesthetic spiritual sociopolitical guidelines in the literary analysis of historical works
Establishing a structured plan to provide high-quality end-of-life care in community settings
Authors: Ramplin Charlotte
Published: February 2019

The purpose of this project was to explore how registered community nurses experienced providing holistic end-of-life care and how having a structured end-of-life care pathway plan would help develop their knowledge and skills, particularly in respect of communication and their ability and confidence in providing evidence-based compassionate care. For some practitioners there exists a lack of confidence surrounding end of life care, which can result in nurses' reluctance to become involved and avoid engaging in those ‘difficult conversations’. Following implementation, early reviews from practice suggest that incorporating the 19 steps of the plan into the delivery of community-based care at end of life has enhanced practice and patient experience.
‘Grassroots dentistry’
Authors: Ellwood Fiona , Reading Sally
Published: February 2019

Dental nurse Fiona Ellwood and dental therapist and hygienist Sally Reading join Dentaid
Roadblock ahead?
Authors: Bissett Julie
Published: February 2019

What's stopping you developing your career? Julie Bissett explores the unexpected barriers to seeking new avenues
Smoking and behaviour change
Authors: Middleton Anna
Published: February 2019

Ex-smoker and dental hygienist Anna Middleton shares some invaluable insights into kicking the habit
Sensory-motor impairments of ipsilesional extremities and its impact on activity limitations following stroke
Authors: Savant Divyarani , Telang Vimal
Published: February 2019

Background/Aims

Stroke can result in various motor and sensory impairments on contralesional as well as ipsilesional limbs. This study examined the impact on activity limitations as a result of sensory and motor impairments of ipsilesional limbs following stroke.

Methods

A cross-sectional study was used to assess 50 adults with stroke (acute: n=6, subacute: n=10, chronic: n=34) and 50 age- and gender-matched typically healthy adults. The Modified Ashworth Scale, the Brunnstrom Approach, Nottingham Sensory Assessment, Star Cancellation Test, Right-Left Orientation Test, Trunk Impairment Scale, Single Leg Stance Test, and the Fugl Mayer Assessment were used to measure outcomes for ipsilesional side impairments. Activity limitations were scored using the Wisconsin Gait Scale and the Motor Assessment Scale.

Results

A comparison of all impairments: tonal, voluntary control, sensation, perception, sitting and standing balance, and coordination of the ipsilesional extremity of persons with hemiparesis with corresponding extremity of typically healthy adults using unpaired t-test, showed significant impairment (P<0.05). Every participant with stroke had at least one impairment on their ipsilesional side, with 8% of participants having only one impairment, 36% had two impairments, 28% had three impairments, 18% had four impairments, 8% had five impairments and 2% had all six impairments on their ipsilesional side. The percentage of participants with stroke presenting with trunk impairment was highest (100%) and that of voluntary control impairment was lowest (24%) on their ipsilesional side. The relationship between identified impairments and activity limitations was calculated using Pearson’s correlation at 0.05 level, which showed a moderate negative correlation with the Wisconsin Gait Scale and a moderate positive correlation with the Motor Assessment Scale.

Conclusions

Ipsilesional impairments present in people with hemiparesis have a significant impact on the activity limitation; hence it is necessary to address ipsilesional impairments along with contralesional impairments.
Femoral morphology asymmetry in hip dysplasia makes radiological leg length measurement inaccurate
Authors: Tamura K. , Takao M. , Hamada H. , Ando W. , Sakai T. , Sugano N.
Published: February 2019

Aims

The aim of this study was to examine whether hips with unilateral osteoarthritis (OA) secondary to developmental dysplasia of the hip (DDH) have significant asymmetry in femoral length, and to determine potential related factors.

Patients and Methods

We enrolled 90 patients (82 female, eight male) with DDH showing unilateral OA changes, and 43 healthy volunteers (26 female, 17 male) as controls. The mean age was 61.8 years (39 to 93) for the DDH groups, and 71.2 years (57 to 84) for the control group. Using a CT-based coordinate measurement system, we evaluated the following vertical distances: top of the greater trochanter to the knee centre (femoral length GT), most medial prominence of the lesser trochanter to the knee centre (femoral length LT), and top of the greater trochanter to the medial prominence of the lesser trochanter (intertrochanteric distance), along with assessments of femoral neck anteversion and neck shaft angle.

Results

The percentages of hips with an absolute difference of > 5 mm in femoral GT and LT lengths were significantly larger in the DDH group (24% for both) compared with those of the control group (2% and 7%, respectively). The femoral length GT of the affected femur was significantly shorter in Crowe I and longer in Crowe IV than that of the unaffected side. The affected-to-unaffected difference of the intertrochanteric distance showed positive correlation with that of the femoral length GT in Crowe I and Crowe II/III, and negative correlation with that of the femoral length LT in the Crowe I and Crowe IV groups.

Conclusion

Hips with unilateral end-stage OA secondary to DDH show significant asymmetry in femoral length between both the greater and lesser trochanter and the knee compared with controls. The intertrochanteric distance was a morphological factor related to femoral-length asymmetry. When undertaking total hip arthroplasty (THA) in the presence of DDH, long leg radiographs or CT measurements should be used to assess true leg-length discrepancy. Cite this article: Bone Joint J 2019;101-B:297–302.
Predictors of mortality in the elderly patient with a fracture of the odontoid process
Authors: Shafafy R. , Valsamis E. M. , Luck J. , Dimock R. , Rampersad S. , Kieffer W. , Morassi G. L. , Elsayed S.
Published: February 2019

Aims

Fracture of the odontoid process (OP) in the elderly is associated with mortality rates similar to those of hip fracture. The aim of this study was to identify variables that predict mortality in patients with a fracture of the OP, and to assess whether established hip fracture scoring systems such as the Nottingham Hip Fracture Score (NHFS) or Sernbo Score might also be used as predictors of mortality in these patients.

Patients and Methods

We conducted a retrospective review of patients aged 65 and over with an acute fracture of the OP from two hospitals. Data collected included demographics, medical history, residence, mobility status, admission blood tests, abbreviated mental test score, presence of other injuries, and head injury. All patients were treated in a semi-rigid cervical orthosis. Univariate and multivariate analysis were undertaken to identify predictors of mortality at 30 days and one year. A total of 82 patients were identified. There were 32 men and 50 women with a mean age of 83.7 years (67 to 100).

Results

Overall mortality was 14.6% at 30 days and 34.1% at one year. Univariate analysis revealed head injury and the NHFS to be significant predictors of mortality at 30 days and one year. Multivariate analysis showed that head injury is an independent predictor of mortality at 30 days and at one year. The NHFS was an independent predictor of mortality at one year. The presence of other spinal injuries was an independent predictor at 30 days. Following survival analysis, an NHFS score greater than 5 stratified patients into a significantly higher risk group at both 30 days and one year.

Conclusion

The NHFS may be used to identify high-risk patients with a fracture of the OP. Head injury increases the risk of mortality in patients with a fracture of the OP. This may help to guide multidisciplinary management and to inform patients. This paper provides evidence to suggest that frailty rather than age alone may be important as a predictor of mortality in elderly patients with a fracture of the odontoid process. Cite this article: Bone Joint J 2019;101-B:253–259.
Are core surgical trainees being trained to operate?
Authors: Hopkins ME , Harris AS , Davids JD , Owens D
Published: February 2019

A national prospective study of tonsil and adenoid surgery between 2004 and 2015.
Results of Salmonella typhi culture in patients with suspected typhoid fever, treated in the Department of Child Health Medical School, Padjadjaran University, Hasan Sadikin General Hospital Bandung
Authors: Sekarwana Nanan , Garna Herry , S. Azhali M.
Published: February 2019

From October to December 1984, examination has been carried out on Salmonella typhi cultures from blood, bone marrow, faeces and urine of 43 patients suffering from suspected typhoid fever treated in the Department of Child Health, Medical Schooll Hasan Sadikin General Hospital, Bandung.It was apparent that among these 43 patients, 51.2% were males and 48.8% females. The greater number of them were more than 5 years old (64.4%). The results of Salmonella typhi cultures were obtained  from 65% of the patients, consisting of 65% positive cultures from bone-marrow and 40% positive cultures from blood that showed a statistically significant difference (p < 0.05).Likewise, the time for matter-sampling for the examinations was based on the culture results, both on blood-culture and that of bone-marrow, statistically a significant was found (p < 0.05), whereas the results of cultures based on previous vaccination history and the administration of chloramphenicol prior to treatment did not differ significantly.It was obviously clear that the results of bone-marrow culture were more successful compared to those from blood culture, so that it should necessarily be emphasized, as to these examinations on culture from each patient with suspected typhoid fever, especially those patients hospitalized during the third week of their illness.
New Perspectives in the Nutrition of Premature and Low Birth Weight Infants
Authors: Wachtel Ursula
Published: February 2019

Everybody in this audience is well aware of the fact that in about the last two decades great advances have been made in fetal and neonatal medicine. Due to the recently gained knowledge in fetal biology as well as in neonatal biochemistry, physiology and pathophysiology a much better understanding of special dietary needs in prematurity and infancy has been achieved. Based on sound scientific background completely new feeding regimens are used today, which have not even been thought of about 20 or 30 years ago and which in turn have considerably contributed to the development of so-called "foods for special dietary purposes."
Toronto’s Smart City: Everyday Life or Google Life?
Authors: Tierney T F
Published: February 2019

In August 2015, Google reorganized its various interests as a conglomerate called Alphabet Inc. Under the new umbrella, Google’s search, data aggregation, and advertising subsidiaries, were joined by Sidewalk Lab and its suite of urban products: high-speed broadband services, Android Pixel2 phone, mobile mapping, autonomous cars, artificial intelligence, smart homes, and all the data captured therein. The City of Toronto’s recent award to Alphabet’s Sidewalk Lab for design services has sparked a heated controversy among urban planners and citizens alike. Toronto’s decision not only signals a different model of professional practice, but it also represents a conceptual shift away from citizen to urban consumer. By engaging a private technology company, one that passively captures data on its customers and then re-sales that data to third parties, Toronto’s smart city points to a significant change in the understanding and practice of contemporary urban planning and design.

Acknowledging the city as a site of disciplinary disruption, this paper introduces Bratton’s stack theory as a way to understand networked urbanism more generally, and Waterfront Toronto specifically. We build on Bratton’s position by closely examining twenty-first century histories and anthropologies related to the Internet, privacy, and the dominance of big data. Our principal concern is with the transformation of personal and environmental data into an economic resource. Seen through that particular lens, we argue that Toronto’s smart city has internalized relations of colonization, whereby the economic objectives of a multinational technology company take on new configurations at a local level of human (and non-human) information extraction – thereby restructuring not only public land, but also everyday life into a zone of unmitigated consumption.
Deep in the Brain: Identity and Authenticity in Pediatric Gender Transition
Authors: Sadjadi Sahar
Published: February 2019

Based on an ethnography of clinical practices around gender-nonconforming and transgender children in the United States, this article explores the cultural and scientific notions of identity that shape this field. It examines the practice of diagnosing true gender identity in the clinic and situates the search for the foundation of identity in the inner depths of the self, and in children as harbingers of authenticity, as part of a broader cultural history. It addresses the scientific substantiation of the faith in innateness (“born this way”) and interiority (“from within”) of identity, as well as their political appeal. This article challenges the often taken-for-granted association of science with materialism—and the distribution of matter-idea along the nature–culture axis—by demonstrating the idealism that drives the siting of identity in the brain. Finally, it questions the assumption that it is the appeal of nature and biology that underlies the cultural attachment to entities such as the gene and the brain as locations for the origin of identity in the contemporary United States. Rather than the nature–culture dyad, this article argues that the internal-external dyad more accurately captures and explains this cultural attachment.
Peluang dan Tantangan Penerapan Cloud Computing (Komputasi Awan) Sebagai Solusi Automasi Kerjasama Antar Perpustakaan
Authors: Christiani Lydia
Published: February 2019

Cloud Computing atau komputasi awan bukanlah sesuatu hal yang baru. Meskipun demikian potensi pemanfaatannya belum sepenuhnya disadari oleh masyarakat luas, terlebih potensinya untuk menjadi sarana automasi kerjasama antar perpustakaan. Ketersediaan vendor infrastruktur, software perpustakaan berbasis web, hingga web browser yang telah populer di kalangan masyarakat merupakan modal awal untuk mengimplementasikan komputasi awan pada berbagai layanan perpustakaan. Meskipun di lain sisi perpustakaan harus menghadapi tantangan seperti pendayagunaan SDM dalam perpustakaan sebagai pengelola sistem perpustakaan itu sendiri, serta investasi dalam pembangunan platform  komputasi awan. Tantangan-tantangan tersebut dapat diatasi dengan membangun kerjasama, baik secara internal dengan sesama perpustakaan, maupun dengan mendorong dukungan pemerintah serta perusahaan-perusahaan dalam bidang teknologi informasi dan komunikasi.
Pengaruh Pemikiran Raymond C Davis tentang Bibliography Instruction terhadap Konsep Literasi Informasi
Authors: Ganggi Roro Isyawati Permata
Published: February 2019

Bibliography instruction pertama kali digagas oleh Raymond C. Davis pada tahun 1881. Sejak dilaksanakan pada tahun 1881 bibliography instruction masih tetap dilakukan, meskipun kemudian diperbaharui dengan konsep yang sesuai dengan perkembangan zaman. Raymond C. Davis sendiri merupakan pustakawan di University of Michigan. Davis dianggap sebagai pionir dalam bibliography instruction  meskipun ia bukanlah orang pertama yang mencetuskan konsep bibliography instruction. Hal ini dikarenakan Davis adalah orang pertama yang melaksanakan bibliography instruction secara formal dan sistematis. Pada perkembangannya muncul banyak istilah terkait bibliography instruction, seperti library instruction, user education, pendidikan pemakai atau library literacy. Gagasan Davis dalam menjalankan bibliography instruction masih digunakan sampai sekarang, hampir semua perpustakaan memberikan pelatihan kepada penggunanya tentang bagaimana cara memanfaatkan sumber daya yang ada di perpustakaan. Perkembangan teknologi informasi khususnya internet membawa pengaruh juga pada pengajaran bibliography instruction. Paul Zurkowski menjadikan konsep instruksi bibliografi sebagai dasar untuk konsep literasi informasi di tahun 1974. Bibliography instruction  oleh Zurkowski dianggap tidak terbatas hanya pengenalan sumber daya di perpustakaan saja, tetapi juga sumber daya informasi di luar perpustakaan. Konsep inilah yang pada akhirnya melahirkan literasi informasi.
Thematic Analysis sebagai Metode Menganalisa Data untuk Penelitian Kualitatif
Authors: Heriyanto Heriyanto
Published: February 2019

Artikel ini berjudul Thematic Analysis sebagai Metode untuk menganalisa Data untuk Penelitian Kualitatif. Tulisan ini bertujuan untuk mendeskripsikan tentang apakah itu thematic analysis sekaligus mengilustrasikan bagaimana metode ini digunakan pada salah satu penelitian kualitatif. Thematic analysis Thematic analysis merupakan salah satu cara untuk menganalisa data dengan tujuan untuk mengidentifikasi pola dan menemukan tema melalui data yang telah dikumpulkan oleh peneliti. Thematic analysis telah digunakan pada beberapa penelitian ilmu-ilmu sosial, termasuk ilmu perpustakaan dan informasi. Artikel ini juga menunjukkan bagaimana thematic analisis ini secara teknis diimplementasikan dalam menganalisa sebuah penelitian yang bertujuan untuk memahami literasi informasi peneliti saat menggunakan open access. Penelitian tersebut menemukan empat tema, yaitu pemahaman tentang open access, institutional repository, publikasi dan diseminasi, dan penelusuran informasi. Selain itu, penelitian ini juga berhasil menemukan hubungan antar masing-masing tema.
Daur Hidup Pengembangan Sistem untuk Otomasi Perpustakaan
Authors: Dewi Athanasia Octaviani Puspita
Published: February 2019

Artikel ini menjelaskan cara mengembangkan sistem otomasi perpustakaan menggunakan siklus hidup pengembangan sistem sesuai dengan Sommervile yang terdiri dari Analisis dan Definisi, Desain Sistem dan Perangkat Lunak, Implementasi dan Pengujian Unit, Integrasi dan Pengujian Sistem, Operasi dan Pemeliharaan. Hal ini diperlukan bagi pustakawan untuk mengetahui bagaimana cara mengembangkan sistem informasi karena sebagian besar pustakawan hanya mahir menggunakan perangkat lunak tetapi belum begitu sensitif terhadap pengembangan perangkat lunak itu sendiri. Harapannya adalah jika pustakawan memahami ini, sistem otomatis akan berjalan maksimal.
Memahami Bagaimana Mahasiswa Melakukan Penelusuran Informasi melalui Academic Databases
Authors: Heriyanto Heriyanto
Published: February 2019

Penelitian ini bertujuan untuk mengetahui sejauhmana kemampuan mahasiswa semester tiga disalah satu program studi di salah satu universitas di Semarang. Melalui pendekatan kualitatif penelitian ini menggunakan observasi dan wawancara sebagai metode pengumpulan data. Data yang terkumpul dianalisis secara induktif dengan mengkombinasikan hasil observasi dan wawancara. Hasil yang ditemukan dari penelitian ini meliputi pemilihan academic databases, identifikasi tiga platform sebagai media penelusuran, memulai penelusuran, dan menyeleksi artikel.
MENINGKATKAN KEMAMPUAN KANJI MAHASISWA MELALUI MEDIA KARTU HURUF KANJI
Authors: Prasetiani Dyah , Diner Lispridona
Published: February 2019

AbstractJapanese character Kanji is difficult for the students who learn Japanese as a foreign language. Bacause Kanji has stroke order, and also Chinese and Japanese ways of reading. Moreover one character of kanji is presenting one meaning, thus the amount of kanji is massive. The informal interview conduct in some students on Semarang State University, Japanese Department, 2nd semester, reveal that students got problems in memorizing the meaning and also the ways of reading and writing kanji. They often find difficulties while combining two kanji characters become a word (jukugo). Some words they didn’t familiar with will cause any further problems such as they didn’t know how to apply it into the sentence. Actually, the text book they use has reading and writing practice sections which is enough and proper to learn by themselves. But sometimes students need to make they own sentences in order to make their memory of kanji more lasting. Since the students admitted that they lacks of practice making sentences, therefore, we conducted an experiment in a class, using kanji card in order to overcome the student’s problems mentioned above. The result shows that this technique is effective and encourages students to: produce jukugo, produce sentences which using the kanji, students feel fun in learning kanji. But, not quite suitable if we conduct it in a large class.
NILAI SOSIAL BUDAYA JEPANG DALAM PERIBAHASA JEPANG YANG MENGGUNAKAN KONSEP BINATANG
Authors: Trahutami Sriwahyu Istana
Published: February 2019

Proverbs conveying animal concepts can be found in almost languages. They are used to express indirectly the spesker’s meaning. The data of the research are taken from Japanese Proverb Dictionary. This study used referential and inferential methods.The methods were used to determine life values in Japanese society or Japanese culture. This analysis reveals that in Japanese proverbs the animal like dog, cat, frog, snake, raccoon, tanuki, fish etc is often mapped on to human beings to expressing human relationship and to show characteristic of the Japanese people and culture.
PENGGUNAAN PARTIKEL ILOKUSI NE DAN YO DALAM TUTURAN BAHASA JEPANG
Authors: Wiyatasari Reny
Published: February 2019

(Title: Use of Illocutionary Particle in Japanese Language). The purpose of this study is to explain the use of illocutionary particles ne and yo, the pragmatic meaning generated from a speech and how the influence of the existence of each of these particles in a speech. Because ne and yo are pragmatic rather than semantic and this nature only occurs in verbal interactions, this article takes data from data sources, such as Japanese dramas and Japanese short stories. The data was collected using the observation method through recording and note-taking techniques, and then analyzed using contextual method.From the results of data analysis it was found that ne particles are used when  a) request confirmation or ensure information, b) request or seek agreement, c) soften speech, and d) marking the feelings felt by the speaker. While yo particles are used when  : a) confirming the question to get a response or reason, b) marking that information (statement) is something new for the listerner, c) emphasizing or affirming a matter/action intended by the speaker in his speech, d) marking speech means encouraging, e) marking utterances that contain expressions of the feeling of the speaker, and f) marking the urge to take action.
MENINGKATKAN KEMAMPUAN KANJI MELALUI MEDIA KANJI GAME ONLINE
Authors: Prasetiani Dyah
Published: February 2019

(Title: Improving The Capabilities Of Agency Through Media Kanji Game Online) Japanese has several types of letters namely hiragana, katakana, kanji, and romaji. Each letter has its own uniqueness. For foreign learners, kanji is considered the most difficult. The results of interviews on the third semester students who followed the Kanji Shochukyu course showed that students often have difficulty in memorizing kanji, often forget the shape so that they are not able to write kanji correctly, and are often confused between read On and Kun. To overcome student difficulties in memorizing kanji, the author tries to use kanji media online game. The method used is experiment with experiment class and control class. The instrument used is postes. The result of the postes shows that the mean value of the experimental class is 82.5 while the control class is 70.1. Keywords: kanji; game online
JUGUN IANFU : DERITA PEREMPUAN DALAM PUSARAN PERANG
Authors: Suliyati Titik
Published: February 2019

(Title: Jugun Ianfu: Woman Suffering In War). The formation of the Jugun Ianfu system was motivated by the war in the context of the Japanese military invasion of other countries. The war has made the physical and mental exhaustion of the Japanese army. This condition resulted in the Japanese army carrying out sexual exploitation brutally by carrying out mass rapes in the territories that were colonized by them. Although Japanese occupation in Indonesia was only 3.5 years, the suffering for Jugun Ianfu lasting forever. Even though most Jugun Ianfu has passed away and the relation between Indonesia and Japan is in a good diplomacy, it does not mean that the events experienced by Jugun Ianfu in the past can be forgotten. The history of Jugun Ianfu can provide pictures that position of women in the past was lower than man and there is no law can protect them. Because there is no legal protection, women are helpless when they experience sexual violence. For this reason, in the present, the government should make legal regulations that to protect women from various violence. In addition, the government is expected to provide the widest opportunity for women to get an education so that in the future women can have advanced thoughts.
Characterizations of ideal cluster points
Authors: Leonetti Paolo , Maccheroni Fabio
Published: February 2019

Given an ideal

{\mathcal{I}}

on ω, we prove that a sequence in a topological space
X is

{\mathcal{I}}

-convergent if and only if there exists a “big”

{\mathcal{I}}

-convergent subsequence. Then we study several
properties and show two characterizations of the set of

{\mathcal{I}}

-cluster points as classical cluster points of a
filter on X and as the smallest closed set
containing “almost all” the sequence. As a consequence, we obtain that the
underlying topology τ coincides with the topology generated by the pair

{(\tau,\mathcal{I})}

.
Periodic impulsive fractional differential equations
Authors: Fečkan Michal , Wang Jin Rong
Published: February 2019

This paper deals with the existence of periodic solutions of fractional differential equations with periodic impulses. The first part of the paper is devoted to the uniqueness, existence and asymptotic stability results for periodic solutions of impulsive fractional differential equations with varying lower limits for standard nonlinear cases as well as for cases of weak nonlinearities, equidistant and periodically shifted impulses. We also apply our result to an impulsive fractional Lorenz system. The second part extends the study to periodic impulsive fractional differential equations with fixed lower limit. We show that in general, there are no solutions with long periodic boundary value conditions for the case of bounded nonlinearities.
Integration of arts into second language curriculum from a Kantian perspective
Authors: Wu Manfred Man-fat
Published: February 2019

This paper explores the benefits of incorporating arts in second language (L2) learning from a Kantian approach. From a Kantian perspective, the use of arts in L2 learning enhances learners’ motivation and engagement in their language learning by focusing on learners’ subjective meanings, lowering the burden of cognition of employing categories for reasoning, lowering learners’ instrumentalism in their language learning through a sense of disinterestedness, allowing a free play between imagination and understanding, providing learners with a purposiveness of form which enhances learners’ cognitive capacity, allowing learners to achieve universal assent, and enhancing learners’ morality. The proposed pedagogical suggestions based on the above benefits are emphasizing the subjective meanings of learners, emphasizing the non-reasoning aspect in arts integration in L2 teaching, highlighting the internal rewards of artistic activities learners engaged in the language classroom, using poetry for the enhancement of imagination, using natural beauty and diverse arts forms, using interactivity, and using arts of different cultures and historical eras in L2 teaching.
Remote Sensing-Based Extraction and Analysis of Temporal and Spatial Variations of Winter Wheat Planting Areas in the Henan Province of China
Authors: Zou Jinqiu , Huang Yinlan , Chen Lina , Chen Shi
Published: February 2019

The aim of this study is to assess the winter wheat planting (WWP) area in Henan Province and investigate its temporal and spatial variations by using remote sensing (RS) technology. A spectral angle mapper (SAM) was adopted to identify the WWP area of each district divided by the hierarchical grades of land surface drought index during 2001-2015. The results obtained show the expediency of monitoring the WWP areas at the regional scale via drought regionalization, which provides a goodness-of-fit R2 =0.933, a mean relative error MRE=49,118 ha, and an overall accuracy up to 90.24%. The major WWP areas in Henan Province were located in Zhoukou, Zhumadian, Shangqiu, Nanyang, and Xinxiang prefecture-level cities. Two representative sites are mountainous districts, with rich water resources or high urbanization rate, which have a low probability of WWP. Both sites exhibited a strongly manifested evolution of WWP areas, which could be attributed to extremely cold weather conditions, crop alternation, the popularization of new varieties, and fast expansion of built-up areas. The results of this study are instrumental in the analysis of crop planting variation characteristics, which should be taken into account in the further decision-making process related to the crop planting strategies.
Up-regulation of key glycolysis proteins in cancer development
Authors: Nowak Nicole , Kulma Anna , Gutowicz Jan
Published: February 2019

In rapid proliferating cancer cells, there is a need for fast ATP and lactate production, therefore cancer cells turn off oxidative phosphorylation and turn on the so called "Warburg effect". This regulating the expression of genes involved in glycolysis. According to many studies, glucose transporter 1, which supplies glucose to the cell, is the most abundantly expressed transporter in cancer cells. Hexokinase 2, is one of four hexokinase isoenzymes, is also another highly expressed enzyme in cancer cells and it functions to enhance the glycolytic rate. The up-regulation of these two proteins has been established as an important factor in promoting development and metastasis in many types of cancer. Furthermore, other enzymes involved in glycolysis pathway such as phosphoglucose isomerase and glyceraldehyde 3-phosphate dehydrogenase, exhibit additional functions in promoting tumor growth in a non-glycolytic way. This review demonstrates the pivotal role of GLUT1, HK2, PGI and GAPDH in cancer development. In particular, we look at how the multifunctional proteins, PGI and GAPDH, affect cancer cell survival. We also present various clinical cancer cases in terms of the overexpression of selected proteins, which may be considered as a therapeutic target.
When Humans Met Superbugs: Strategies to Tackle Bacterial Resistances to Antibiotics
Authors: Bravo Alicia , Ruiz-Cruz Sofia , Alkorta Itziar , Espinosa Manuel
Published: February 2019

Bacterial resistance to antibiotics poses enormous health and economic burdens to our society, and it is of the essence to explore old and new ways to deal with these problems. Here we review the current status of multi-resistance genes and how they spread among bacteria. We discuss strategies to deal with resistant bacteria, namely the search for new targets and the use of inhibitors of protein-protein interactions, fragment-based methods, or modified antisense RNAs. Finally, we discuss integrated approaches that consider bacterial populations and their niches, as well as the role of global regulators that activate and/or repress the expression of multiple genes in fluctuating environments and, therefore, enable resistant bacteria to colonize new niches. Understanding how the global regulatory circuits work is, probably, the best way to tackle bacterial resistance.
A Simplified One-Dimensional Mathematical Model to Study the Transient Thermal Behavior of an Oxidation Catalyst with Both Low and High Levels of CO Concentration at the Inlet
Authors: Mohapatra Priyabrata , Mittal Mayank
Published: February 2019

In recent years, the permissible limits of engine exhaust emissions are reduced considerably. Hence a quick warm-up and high conversion efficiency of the catalyst system is essential to meet upcoming stringent emission regulations. In the present work, the transient thermal behavior of an oxidation catalyst is studied using a one-dimension mathematical modeling approach with the focus on CO oxidation for dual-fuel engine application. At first, the heat generation due to chemical reactions is considered negligible for studying the warm-up behavior. Upon obtaining a good agreement between predicted warm-up temperature profiles with available literature data, the effect of an electrical heater on the warm-up behavior is investigated. The model is then extended by incorporating heat generation due to CO oxidation. A simplified reaction rate model is considered in order to reduce the computational complexity. It is observed that the simplified model agrees well with the experimental data for both low and high levels of CO concentration at the inlet, typical in dual-fuel technology when an engine is operated under diesel and dual-fuel modes, respectively.
Diagnostic error, quality assurance, and medical malpractice/risk management education in emergency medicine residency training programs
Authors: Lewis Jason J. , Rosen Carlo L. , Grossestreuer Anne V. , Ullman Edward A. , Dubosh Nicole M.
Published: February 2019

Background

Diagnostic errors in emergency medicine (EM) can lead to patient harm as well as potential malpractice claims and quality assurance (QA) reviews. It is therefore essential that these topics are part of the core education of trainees. The methods training programs use to educate residents on these topics are unknown. The goal of this study was to identify the current methods used to teach EM residents about diagnostic errors, QA, and malpractice/risk management and determine the amount of educational teaching time EM programs dedicate to these topics.

Methods

An 11-item questionnaire pertaining to resident education on diagnostic errors, QA, and malpractice was sent through the Council of Emergency Medicine Residency Directors (CORD) listserv. Differences in the proportions of responses by duration of training program were analyzed using chi-squared or Fisher’s exact tests.

Results

Fifty-four percent (91/168) of the EM programs responded. There was no difference in prevalence of formal education on these topics among 3- and 4-year programs. The majority of programs (59.5%) offer fewer than 4 h per year of additional QA education beyond morbidity and mortality rounds; a minority of the programs (18.8%) offer more than 4 h per year of medical malpractice/risk management education.

Conclusions

This needs assessment demonstrated that there is a lack of dedicated educational time devoted to these topics. A more formalized and standard curricular approach with increased time allotment may enhance EM resident education about diagnostic errors, QA, and malpractice/risk management.
Die Fragmentierung der gegenwärtigen Philosophie am Beispiel der Philosophiegeschichte
Authors: Rescher Nicholas
Published: February 2019

It can be argued that we live in a golden age for the history of philosophy: more relevant historiographical works in the field are being published today than ever before. The present paper tries to explain this as an effect of the exponential quantitative and qualitative expansion of philosophy, its subdisciplines and its fields of research since at least the mid-twentieth century. It then explores some of the consequences of these current trends and the challenge they represent for any relevant effort in history of philosophy today.
Was ist eine böse Handlung?
Authors: Goldberg Zachary J.
Published: February 2019

What is the nature of evil action? My thesis is that perpetrators and victims of evil inhabit an asymmetrical relation of power; the strength of the more powerful party lies in its ability to exploit the other’s fundamental vulnerability, and the weaker party is vulnerable precisely insofar as it is directly dependent on the more powerful party for the satisfaction of its fundamental needs. The fundamental vulnerabilities that are exploited correspond to features essential to our humanity (ontological), moral personhood (personal), and individuality (characteristic). These kinds of vulnerabilities are both constituted by and engender fundamental needs and give rise to direct dependencies on others to satisfy or to refrain from interfering with the satisfaction of fundamental needs. The unambiguous exploitation by the more powerful agent on whom the vulnerable directly depend is characteristic of evil action. Although I do not claim that the exploitation of ontological, personal, and characteristic vulnerabilities necessarily results in evil, it does typify it.