bluuebunny/crossref_metadata_2025 huggingface dataset:
Mouthwash Preparation Using Stevia and Neem Based Silver Nanoparticles and Its Cytotoxic Activity
Authors: Palanivel Nandini , Priyadharshini R , Rajeshkumar S , Sinduja Palati
Published: February 2023

Introduction: Azadirachta indica (Neem) may be a rapid-growing plant even in severe drought which shed most of its
leaves. The branches are wide and spreading. In this present investigation, we have prepared mouthwash using Stevia and
Neem-based silver nanoparticles.
Materials And Methods: Azadirachta indica and Stevia rebaudiana plant powder form was taken. 1g of Neem and Stevia
extract powder mixed with 100ml of distilled water and then it was boiled, cooled and filtered with filtered paper and
allowed to settle and the extract mixture was found to be 50ml and filtered.
Results And Discussion :The plant had exhibited a potent cytotoxic effect at higher concentrations. Extracellular synthesis
of silver nanoparticles using Neem and Stevia was primarily identified by visual identification; the appearance of silver
and whitish colour in reaction mixture indicates nanoparticles.
Conclusion :The present study revealed that the silver nanoparticles can be synthesised in a simple eco-friendly method
using Neem and Stevia .
Synergistic Activity of Moringa Oleifera and Thyme Vulgaris Essential Oil Against Streptococcus Mutans: An Observational Study
Authors: Karunakaran Sadhana , Sinduja Palati , Priyadharshini R , Ganesh P
Published: February 2023

Background: Dental caries still remain a highly prevalent disease among all age groups especially children. It is caused
due to repetitive and/or prolonged demineralization of tooth enamel caused by exposure to low pH from organic acids
produced by acidogenic oral bacteria during fermentation of dietary carbohydrates. Streptococcus mutans is a facultative
anaerobic , gram positive cocci commonly found in the human oral cavity which plays an important role in causing dental
caries. Moringa oleifera Lam. (drumstick tree) is a Moringaceae family member which possesses a variety of advantageous
biological properties, such as immunomodulatory, anticancer, antiulcer and antimicrobial properties. Thymus vulgaris is
a pleasant smelling perennial shrub which has a direct influence on many bacteria species. The use of combinations of
these two EOs and their components are thus a new approach to increase the antimicrobial efficacy of EOs , taking
advantage of their synergistic and additive effects.
Materials and methods: The broth microdilution method was used to determine the minimum inhibitory concentration(MIC)
of the essential oils. The MIC of Moringa, Thyme and combination of the both essential oils against S.mutans which were
used in the assay were assessed at a different concentration level.
Results: The antimicrobial activity of M.oleifera, T.vulgaris and combination of both the essential oils was proven with the
MIC value of 2.5%v/v, 0.03906% and 0.03906% respectively.
Conclusion: The combination of Moringa oleifera and Thymus vulgaris essential oil can be used as a good antimicrobial
agent to treat various Streptococci borne oral infections. Further incorporation of this oil into the drug formulations is
also recommended to treat S.mutans borne oral as well as systemic infections.
Anti-Inflammatory Activity and Antimicrobial Activity Against Common Oral Pathogens of Cyanthillium Cinereum - An Invitro Study
Authors: Suresh Sushanthi , Leelavathi L , Rajeshkumar S , Indiran Meignana , Priyadarshini Jayaseelan
Published: February 2023

Background: Cyanthillium cinereum known as Poovamkurunilla in Tamil is one among the traditional medicinal plants
which has proven properties.
Aim: Hence, this study is aimed to evaluate the antimicrobial and anti-inflammatory properties of Cyanthillium cinereum
in two groups.
Methodology: The oral pathogens such as Streptococcus mutans, Staphylococcus aureus and Enterococcus faecalis and C.
albicans were used to assess the antimicrobial efficacy of Cyanthillium cinereum in two groups(Group 1 - Aqueous extract
of C.Cinereum leaves; Group 2 – C.Cinereum whole plant using agar well diffusion method at various concentrations that
ranges from 25 µL, 50 µL and 100 µL. Anti-inflammatory activity was evaluated using protein denaturation assay. Statistical
analysis was performed using SPSS version 23. Independent t test and One-way ANOVA were used for measure between
group analysis and Repeated measures ANOVA were used for measure within group analysis.
Results: Increasing the concentration increases the response too against oral microbes. Group 1 shows better antimicrobial
properties than group 2. Statistically significant differences were found on all concentrations taken into consideration.
Whereas both the groups show equal anti-inflammatory activity when compared with diclofenac. Statistically significant
difference was found on all comparisons except Group 1 versus Group 2 in all the concentrations (p=0.358).
Conclusion: The study revealed that C.Cinereum leaves exhibit strong antimicrobial activity against oral microbes except
Candida albicans. Both Group 1 and Group 2 exhibit better anti-inflammatory activity than standard values. Further it has
to be tested for its cytotoxicity and antioxidant activity for future usage of Cyanthillium cinereum in applications in the
pharmaceutical industry.
Assessment of the characterization antimicrobial and green synthesis of magnesium oxide nanoparticles using Psydium guajava - in-vitro analysi
Authors: Rajalakshmi S , Subhasree R , Easwaramoorthy Rajalakshmanan , Nesappan Thiyaneswaran
Published: February 2023

Aim: To assess the characterization, antimicrobial activity of green synthesised magnesium oxide nanoparticles using
Psydium guajava leaves.
Materials And Methods: Psydium guajava leaves were dried and ground, of which 2 g of the powder was used for the
study.the powder was then dissolved in 100ml of distilled water. 1 mg of magnesium chloride salt was dissolved in 20 ml
of distilled water. Both the solutions were mixed and subjected to centrifuge. After the preparation of the nanoparticle,
it was subjected for further investigation like SEM analysis, EDAX, UV-VIs, cytotoxicity and anti microbial tests. The
cytotoxicity was investigated using a brine shrimps bioassay.The number of surviving naupli cells were manually counted
under dissection microscope. The antibacterial activity was examined against four bacterial strains- E.coli,
E.fecalis,S.aureus,P.aurogenosa by agar well diffusion method .The inoculated plates were incubated overnight (for about
24 hours at 37 degree celsius) and the inhibition zone around the nanoparticle solution was calculated. The antimicrobial
tests were carried against standard antibiotic and the results were tabulated.
Results: SEM analysis showed a particle size of 70 nm and the UV -Visible spectroscopy showed a peak at 320nm confirming
the presence of magnesium oxide nanoparticles that is prepared using Psydium guajava. Cytotoxicty tests revealed that
83% of the brine shrimp cells survived .The anti microbial tests revealed that the nanoparticle was effective against two
micro-organisms -S.aureus and E.fecalis and their zone of inhibition was nearly equal to that of standard antibiotic against
which the organisms were incubated.
Conclusion: Psydium guajava synthesized magnesium nanoparticles were found to have good cytotoxicity and acceptable
anti-microbial activity especially against two most commonly harbouring micro-organism(S.aureus and E.faecalis) .Hence
they can be extended for use in soft tissue healing.
Main mites associated with dermatopathies present in dogs and other members of the Canidae family
Authors: Thomson Pamela , o Nicole , ez Andrea
Published: February 2023

Dermatological diseases of parasitic origin are one of the most frequent in the clinical practice of dogs and cats. Mites such as Sarcoptes scabiei, Otodectes cynotis, Demodex canis, and Cheyletiella spp., they commonly affect domestic dogs. However, the impact generated by these mites on populations of wildlife animals and the mechanisms involved in their epidemiological dynamics are still not clear. In recent decades, the migration of populations and their interaction with domestic environments and vice versa have generated a worrying threat due to the transmission of some of these ectoparasites. Some reports have suggested that sarcoptic mange represents an emerging threat to wildlife. given the outbreaks of greater magnitude and geographical extension.

The objective of this review is to contribute to the state of the art of the main mites that cause dermatopathies in members of the Canis Lupus Familiaris family and other members of the Canidae family. For this, a systematic search was carried out in the embase and pubmed databases.

Infections caused by mites, mainly scabies, continue to be diseases with a worldwide distribution, affecting mammals and humans. Although they are long-standing diseases, the effects that are generated in wild canids are still unknown. A comprehensive evaluation is required to generate guidelines in favor of the conservation of some species of foxes and wolves present in the different regions of the world.
Long-term histological effects of high-dose prednisolone administration on the mitral valve in normal Beagle dogs
Authors: Tanaka Sachiyo , Suzuki Shuji , Shimura Misaki , Kawana Asaka , Tanaka Aki , Soeta Satoshi , Hara Yasushi
Published: February 2023

Background: In recent years, left ventricular hypertrophy and cardiac dysfunction have been reported in human and canine patients with hypercortisolism (HAC) and in dogs treated experimentally with high-dose prednisolone. However, to our knowledge, there have been no reports on the effects of hyperglucocorticism (HGC) on the mitral valve (MV).
Aim: This study aimed to compare the MV in dogs treated with high-dose prednisolone with that in healthy dogs to investigate the effects of HGC on the MV.
Methods: We investigated the effects of HGC on the MV by comparing samples obtained from high-dose glucocorticoid-treated (P) and healthy (C) dogs. The P group included healthy Beagle dogs (n = 6) treated with prednisolone (2 mg/kg, bid, po) for 84 days and the C group included healthy Beagle dogs (n = 6) euthanized for unrelated reasons. The anterior and posterior mitral leaflets (AML and PML, respectively) from both groups were harvested and stained with hematoxylin–eosin, Alcian blue, and Masson trichome. Additionally, adiponectin (ADN) and glucocorticoid receptor immunohistochemistry were performed. Histological evaluation was performed in the atrialis, spongiosa, fibrosa, and all layers of the proximal, middle, and distal regions of the AML and PML.
Results: The proportion of the spongiosa layer thickness to the total thickness was higher in the P than in the C group (proximal and middle AML). However, the proportion of the fibrosa layer thickness to the total thickness was lower in the P than in the C group (middle PML). Areas of acidic sulfated mucosubstance deposition were smaller in the fibrosa layer and all layers (middle AML), while those of collagen deposition were smaller in the spongiosa and total layers (proximal and middle AML), in the P than in the C group. Additionally, ADN expression in the spongiosa layer was higher in the P than in the C group (middle AML).
Conclusion: These findings suggest that long-term administration of synthetic glucocorticoids induces histological changes in the MV. These changes may lead to MV dysfunction in dogs with HGC.
Electric autonomous tractors in Swedish agriculture : A systems analysis of economic, environmental and performance effects
Authors: Lagnelöv Oscar
Published: February 2023

Use of battery-electric vehicles has become common in different sectors, as a measure to reduce greenhouse gas emissions. Driveline electrification in agricultural machinery could reduce emissions and increase driveline efficiency, but implementation has been hindered by the low energy-carrying capacity of batteries compared with conventional fuels. Combining battery-electric drivelines and autonomous operation would provide important synergies by mitigating or eliminating many of negative aspects of electrification, while retaining the benefits from both systems. This thesis evaluated the potential and analysed the intricate workings of a battery-based autonomous electric vehicle system by applying systems analysis, economic analysis and life cycle assessment, through simulations and modelling. The vehicle system was evaluated on a theoretical Swedish grain farm of 200 ha using a conventional cropping system. Soil compaction, battery ageing, queueing dynamics, field trafficability, energy storage and weather effects were all included in simulations. This allowed comparison of performance, cost and environmental impacts for a conventional fieldwork tractor and a system with several smaller autonomous battery-electric tractors. The evaluation showed that the autonomous electric tractors were able to match or exceed the daily work rate of the conventional tractor, while reducing energy use (by 47-75%), lowering annual costs (by 32-37%) and reducing soil compaction. The environmental impact was generally also lower, with up to a 74% reduction in greenhouse gas emissions over the system’s life cycle. These results indicate great potential for autonomous electric tractors in future agricultural fieldwork, as combining the electric driveline and autonomous technologies allowed the benefits from both to be used to greater effect than either by itself.
The Impact of Income Inequality on Health of Chinese Residents — Decomposition Based on Individual Effect and Macro Effect
Authors: Wang Songtao , Luo Minqian , Li Bin
Published: February 2023

This paper reviews the mechanism of income inequality affecting residents' health, and proposes a new measurement method to decompose the micro mechanism and macro effect of income inequality affecting residents' health. Based on the provincial data onto 1990, 2000 and 2010, an empirical analysis using the multi-period mixed cross-sectional data (Pool Data) model shows that income inequality has a significant negative impact on health in China. The method constructed in this paper is used to decompose the contribution rate of macro effect and individual effect. The results show that the negative impact of macro effect accounts for 27.7%, while the impact of micro effect accounts for 72.3%. With the continuous improvement on GDP per capital in China, the impact of macro effect of income gaps between life expectancy is getting smaller and smaller. The macro effect contribution rate decreases year by year. Therefore, on the one hand, it is necessary to reduce income inequality, but also to take targeted measures to reduce the negative impact of income inequality on individual health.
Technologies in the Pharmaceutical Industries and Medical Health Care
Authors: J Yuktha H , Kulkarni Gururaj S , Shetty Athmaja , Paarakh Padmaa M
Published: February 2023

This review aims to illustrate upcoming technological developments in the pharmaceutical industries and healthcare facilities may look in the near future. In order to achieve this, we examine recent technologies and advanced medical developments in healthcare as well as in the pharma industries. Such as Artificial intelligence which provides an understanding between process parameters and different formulations. Blockchain is a sophisticated database that stores data in a way that makes it impossible to alter or hack the system. Clouding Technology enhances the drug discovery process. In the Future hospitals will need room for scanning and 3D printing since they can create virtually anything, including medical devices and human body components, and also produce drugs for every individual. Robotics is widely used in surgery as well as in chemical handling in laboratories. IT (Information Technology) is a database that helps in gathering information in surgery departments, hospitals, labs, and clinics. Our geriatric populations' quality of life can be maintained with the aid of new, technologies and innovations in health care. To overcome these obstacles, medical technology, as well as pharma industries, as well as pharma industries must unite and promote, high-quality methods while incorporating them into many related fields.
Creating an Animal Identifier Model by Deep Learning
Authors: Aziz Md. Naeem
Published: February 2023

This paper attempts to make a YOLOv3 model which can detect and identify animals. YOLOv3 is a deep-learning technique for object identification. Suppose, there’re many animals in a place. When the picture of the animals are converted as picture data and then, if the researcher input that picture data in the research model and searches for a cat from that picture data and if there’s a cat in that picture data then the research model, the YOLOv3 model can identify and identify the cat from that picture data easily. The research model, the YOLOv3 model will do the same for other animals too. So, the researcher makes a model which can identify animals and show which animal it is by using a deep-learning algorithm called YOLOv3.
The Connected Geodetic Global Domination Number of
a Graph
Authors: Xaviour X. Lenin , Chellathurai S. Robinson
Published: February 2023

A set S of vertices in a connected graph {G=(V,E)} is called a geodetic set if
every vertex not in S lies on a shortest path between two vertices from S. A set D of vertices in G is called a dominating set of G if every vertex not in D has at least one neighbour in D. A geodetic dominating set S is both a geodetic and a dominating set. A set S is called a geodetic global dominating set of G if S is both geodetic and global dominating set of G. The geodetic global domination number (geodetic domination number) is the minimum cardinality of a geodetic global dominating set (geodetic dominating set) in G. In this paper we introduced and investigate the connected geodetic global domination number of certain graphs and some of the general properties are studied.
A Review on Iot Enabling Technologies and Back-End Data-Sharing Model
Authors: Reddy Anumandla Mounika
Published: February 2023

The Internet of Things (IoT) is an important topic in the modern technology industry, policy, and additionally layout cycles and additionally has wound up being headline updates in both the customized media as well as the popular media. This innovation is established in a wide range of online products, systems, along with sensing units, which take advantage of advancements in finding out electrical power, digital units miniaturization, and also system linkups to provide brand-new abilities not earlier possible. A riches of seminars, data, and also newspaper articles cover and likewise doubt the achievable effect of the "IoT makeover"-- coming from new market choices and also solution types to fears about security, privacy, as well as specialized interoperability.
Verdier, holdninger og kompetanseutvikling i et utdanningsperspektiv
Authors: Jermstad Linn´ea K. , Myklebust Marit , Toppe Anne Lene B. , Vesteraas Renate C.J. , Ryland Lill Krestin , Holovchuk Svitlana , Meyer Grete Skjeggestad , Oppedal Kjell , Furnes Gila Hammer , Jokstad Gunnvi Sæle , Landro Torgeir , Omland Solveig , Dahlstrøm Hilde Kristin , Norheim Bård , Sæle Ove Olsen , Dahle Margunn Serigstad , Skattør Tone Helene , Andersland Inge , Sæverot Ane Malene , Andvik Erik , Kjelsvik Bjørghild , Flatås Robert Mjelde , Johannessen Baard , Kaldahl Anne-Grete , Skotheim Torhild , Schön Eldbjørg , Småland Erik G. , Økland Øyvind
Published: February 2023

Denne vitenskapelige antologien presenterer ulike forskningsarbeider som tar for seg verdier, holdninger og kompetanseutvikling i et utdanningsperspektiv. Boken dekker et bredt spekter av fagområder, fra journalistikk og interkulturell kommunikasjon til teologi, pedagogikk og barnehage- og grunnskolelærerutdanning.
Yrkesutøvelse er i dag basert på kunnskap, refleksjon og profesjonsverdier. Disse verdiene har en moralsk karakter og innebærer en forpliktelse til å sette barnet, eleven eller studenten, samt samfunnets interesser foran egne interesser. Samtidig krever samfunnet at kvaliteten i utdanningen forbedres og at studiene forbereder den enkelte på morgendagens krav.
Når verdier enten danner et intensjonsgrunnlag for handling eller skaper retning for handling, vil verdiene bli et fortolkningsgrunnlag i vurderinger av våre profesjonelle handlinger. Disse handlingene og refleksjonene analyseres i antologiens 17 kapitler, skrevet av 30 bidragsytere fra akademia med lang kjennskap til praksisfeltet. Boken gir dermed leserne et dypere innblikk i sammenhengene mellom verdier, yrkesutøvelse og kvalitet i utdanningene, og vil være en viktig ressurs for forskere, undervisere, studenter og andre med interesse for denne tematikken.
Hizkuntzen erabileraren kale-neurketa. Euskal Herria, 2021. Emaitza nagusiak
Authors: ALTUNA ZUMETA OLATZ , IÑARRA ARREGI MAIALEN , BASURTO ARRUTI ASIER , URANGA ARAKISTAIN BELEN
Published: February 2023

Artikulu honetan Euskal Herrian 2021ean eginiko Hizkuntzen erabileraren kale-neurketaren
zortzigarren edizioaren emaitza nagusiak aurkeztuko dira. 1989. urtean abian jarritako ikerketak
hizkuntzen presentzia kuantifikatzen du kalean entzundako elkarrizketa informalak behatuz. Datu-bilketa
zabalak aukera ematen du Euskal Herri mailako, lurraldeetako, eskualdeetako, eta hiriburuetako
emaitzak ezagutzeko; baita adinaren, sexuaren eta haurren presentziaren eragina aztertzeko ere. Euskal
Herriko kaleetako hizkuntza-erabilerari buruz datu enpirikoak eskuratzeaz gain, datu horiek aztertzea
eta interpretatzea da ikerketaren helburua, eta, batez ere, euskararen biziberritze-prozesuari begira bere
ekarpena egin nahi dio hausnarketarako, hizkuntza-politikak erabakitzeko eta hizkuntza-plangintza diseinatzeko
ezagutza-tresnak eskainiz. • Hitz gakoak: Kale-erabilera, euskara, biziberritzea, erabilera,
informala, behaketa, kale-neurketa.
Zer erakusten du adinak kale-erabileran?
Authors: MARTINEZ DE LUNA IÑAKI
Published: February 2023

Euskararen kale-erabiera (EKE) adin-taldeka aztertuz, emaitza deigarri eta joera esanguratsuekin
egiten dugu topo. Halakoak eta beren zergatiak ulertzeko, soziolinguistikak zenbait kontzeptu
eta ikuspegi baliotsu eskaintzen ditu, hala nola hizkuntza-sozializazioa, hizkuntza-identitatea,
gizarte-araua eta abar. Izan ere, hiztun elebidun edo eleaniztunek ez dute ausaz hautatzen unean-unean
erabiliko duten hizkuntza, baizik eta egoera bakoitzeko baldintza sozialen arabera. Horietako batzuk
islatzen dira Euskal Herriko hizkuntzen erabileran. Abiapuntu horretatik abiatuz, saiatzen gara hemen
adin-taldeen EKE maila ezberdinak ulertzen, batetik, eta balizko interpretazioez hausnartzen, bestetik.
• Hitz gakoak: Hizkuntza-sozializazioa, hizkuntza indarberritzea, hizkuntza-transmisioa, identitatea,
gizarte-araua.
Euskararen erresaka etenezina eta Sisifo
Authors: AIERDI URRAZA XABIER
Published: February 2023

Euskararen biziberritze-prozesuan hizkuntzaren ezagutza eta erabilera ari dira garatzen
aldi berean. Ezagutzari dagokionean, espero zena baino gehiago hazi dela esan daiteke, eta erabileraren
alorrean ezin ukatuzkoa da irabazi kualitatiboa, espazio sozialetan, gai espezializatuetan, eta estandarizazio
kulturalean asko hazi baita. Euskal Herriko kaleetan egiten den euskararen erabileraren bilakaerak,
ordea, frustrazioa sortzen du. Baina, arretaz begiratu behar zaie, nahia eta errealitatea baldintzatzen
duten ezaugarriei. Kontuan izan behar dira gizartea eraldatu eta erabilera mugatzen duten gizartearen
ezaugarri soziologikoak; demografikoak (biztanleriaren zahartzea, egiturazko migrazio-mugimenduak,
lurralde desberdinetako euskaldunen dentsitateak), teknologikoak (komunikazio-modu eta produktu
berriak), ekonomikoak eta kulturalak.
Aurrerantzean ere, hizkuntza-politikak diseinatzeko orduan, arretaz aztertu beharko dira honako elementu
hauek: etorkinen integrazioa ziurra ala ahula den, enplegu-munduko berriak zein diren, hezkuntzaren
segregazio potentziala, goranzko mugikortasunaren ahultzea, klase sozialen araberako praktika
linguistikoak eta, euskara tarteko, euskal elite mugatu berri baten arriskua. Horiek guztiak kontuan
izanda, eta sor daitekeen gatazka politikoaren arriskua alboratuz, hartu beharko dira erabakiak, ahalik
eta gizarte kohesionatu zabalenean oinarritutako euskararen biziberritze-plangintza diseinatzeko. •
Hitz gakoak: euskara, immigrazioa, hizkuntza-plangintza, klase soziala.
PROGRAMAS DE MELHORAMENTO GENÉTICO COM ENFOQUE PARTICIPATIVO
Authors: Sanglard Demerson Arruda , Silveira Ana Carolina Ataide , Alves Jefferson Joe Moreira , Gomes Luan Souza de Paula , Teixeira Matheus Henrique , Amorim Phelipe Souza , Batista Flávia Échila Ribeiro
Published: February 2023

Esta proposta visa promover o desenvolvimento de agricultores familiares do município de Montes Claros-MG, a partir do manejo da diversidade genética de milho com enfoque na agrobiodiversidade, levando em conta critérios de sustentabilidade ambiental. No contexto de um agroecossistema funcional, ambientes marginais possuem uma lógica própria no estabelecimento de espécies e que não se repete em um centro de pesquisa. Portanto, esta proposta prevê a execução de estratégias de avaliação, produção e melhoramento participativo em milho visando o desenvolvimento de variedades adaptadas aos ambientes com estresses específicos. Espécies de adubos verdes serão avaliadas em diferentes sistemas com manejo agroecológico, no qual diferentes culturas, incluindo o milho, serão consorciadas ou cultivadas em rotação. Espera-se que as estratégias de execução promovam a multiplicação de polos locais em comunidades rurais do município, incluindo seus distritos, adotando-se o desenvolvimento local sustentável (DLS). O milho será utilizado como espécie indicadora e de referência metodológica durante a execução das ações que compõem o projeto: (i) Diagnósticos locais participativos; (ii) Manejo da diversidade genética do milho e espécies de adubos verdes em sistemas agroecológicos e; (iii) Cursos de capacitação. O desenvolvimento das ações do projeto contribuirá para a agricultura contextualizada ao semiárido mineiro, resultando em oferta de alimentos saudáveis, de baixo custo e maior segurança alimentar.
Analiza wynagrodze inynierw budownictwa na koniec roku 2022
Authors: Kaczorek Krzysztof
Published: February 2023

W niniejszej pracy przeanalizowano prb 5023 inynierw budownictwa pod ktem ich zarobkw w zalenoci od brany, stau pracy, wielkoci miejscowoci oraz czasu pracy. Otrzymane wyniki zostay przedstawione w formie tabelarycznej oraz poddane analizie i krytycznej ocenie. Ponadto porwnano otrzymane dane z danymi pozyskanymi pod koniec 2021 roku, na podstawie czego wycignito wnioski odnonie do zmian pac budowlanej kadry inynierskiej w Polsce. W zwizku z wieloma problemami, z ktrymi zmagaa si brana budowlana w roku 2022 (wysoka inflacja, chaos w sferze podatkowej, wzrost cen energii, wpyw pandemii COVID-19oraz agresji Rosji na Ukrain), po raz pierwszy w badaniu wprowadzono pytanie dotyczce oglnych nastrojw panujcych wrd budowlanej kadry inynierskiej.
IMPLANT-PROSTHETIC REHABILITATION OF EDENTULOUS COMPLICATIONS IN A HOMEOSTATIC CONTEXT
Authors:   University Professor, The Faculty of Dental Medicine, “Grigore T. Popa” Univ. of Medicine and Pharmacy, Iasi, full member in AOSR and ASM, FORNA Norina , AGOP-FORNA Doriana ,   Associate Professor, The Faculty of Dental Medicine, “Grigore T. Popa” Univ. of Medicine and Pharmacy, Iasi, Corresponding member of AOSR, TOPOLICEANU Claudiu ,   Lecturer, The Faculty of Dental Medicine, “Grigore T. Popa” Univ. of Medicine and Pharmacy, Iasi, ROŞOIU Natalia ,   Prof. Emeritus PhD Faculty of Medicine University “Ovidius” Constanta; Academy of Romanian Scientists
Published: February 2023

The degree of patient damage and the severity of local and loco-regional complications influence the way reconstruction is planned and the stages of implant-prosthetic therapy. Pre-operative analysis of the dimensional parameters of the implant sites (height, width, density) can be performed by means of applications using CBCT images or based on software programs specialized in pre-implant analysis and virtual planning of dental implant positioning. Effective management of complications of partial denture requires interdisciplinary collaboration (implantology, prosthodontics, oral surgery, anesthesia-sedation) both in terms of rehabilitation of loco-regional and local complications, reconstruction of implant sites, implant stage and design of future prosthetic work. The implant-prosthetic treatment plan should focus both on reconstruction of the mucosa-bone support and on ensuring the homeostasis of the stomatognathic system in the context of restoring biomechanical and functional conditions through fixed or removable prosthetic restorations with implant support.
A SHORT EDITORIAL VIEW ON THE RELEVANCE OF EXOSOMES IN SOME NEUROPSYCHIATRIC MANIFESTATIONS - MODEL STUDIES
Authors:   Department of Biology, Faculty of Biology, Alexandru Ioan Cuza University, B dul Carol I, no 11, 700506 Iasi, Romania, RARINCA Viorica , NICOARA Mircea ,   Department of Biology, Faculty of Biology, Alexandru Ioan Cuza University, B dul Carol I, no 11, 700506 Iasi, Romania, CIOBICA Alin ,   Department of Biology, Faculty of Biology, Alexandru Ioan Cuza University, B dul Carol I, no 11, 700506 Iasi, Romania; Center of Biomedical Research, Romanian Academy, B dul Carol I, no 8, 700505 Iasi, Romania; Academy of Romanian Scientists, Splaiul Independentei nr. 54, Sector 5, 050094 Bucuresti, Romania, MAVROUDIS Ioannis ,   Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds LS2 9JT, UK
Published: February 2023

Exosomes are a class of extracellular vesicles derived from cells of endosomal origin and typically have a diameter between 40 to 100 nm, being the smallest type of extracellular vesicle. Although in recent years, the use of exosomes in experimental studies has increased, currently there are few studies that have as a research subject the neurobehavioral changes that exosomes have on model organisms. For this reason, our group is further looking to develop and apply the methodology regarding the neurobehavioral changes that exosomes have on zebrafish (Danio rerio). Thus, we present here a short editorial view on the relevance of exosomes in some neuropsychiatric manifestations-models studies, as wel as some of our future plans in this new area of reearch.
DISTRIBUTION AND ABUNDANCE OF THE MACROZOOPLANKTON COMUNITY IN THE BLACK SEA IN 2021
Authors:   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, Harcotă George Emanuel ,   Faculty of Biology, University of Bucharest, Bucharest, Romania, BIȘINICU Elena ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, TABARCEA Cristina ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, Țoțoiu Aurelia ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, FILIMON Adrian ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, ABAZA Valeria ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, BOICENCO Laura ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania, TIMOFTE Florin ,   Scientific Researcher, National Institute for Marine Research and Development “Grigore Antipa”, Constanța, Romania
Published: February 2023

This paper focuses on the dynamics of four jellyfish species, Aurelia aurita, Beroe ovata, Mnemiopsis leidyi and Pleurobrachia pileus, from the Black Sea. The samples were taken in time of two expeditions in 2021 (May-June and August-September). Aurelia aurita species was dominant in terms of biomass due to its large size, The density of the species Pleurobrachia pileus recorded high values, in the north, but also between the isobaths of 40-80 m. The density of the species Mnemiopsis leidyi was higher in the southern and central area of the Romanian Black Sea. Because jellyfish feed on zooplankton organisms, the eggs and larvae of commercially important fish, high densities of jellyfish can produce direct decreases in the trophic chain by reducing the biomass of zooplankton, and fish eggs and larvae.
STUDY REGARDING INDUSTRIAL ROBOT’S DIGITAL TWIN DESIGN IN CAD-CAM SOFTWARE
Authors:   Faculty of Industrial Engineering and Robotics, University POLITEHNICA of Bucharest, ŞTEFAN Ana-Maria , ANANIA Dorel ,   Faculty of Industrial Engineering and Robotics, University POLITEHNICA of Bucharest
Published: February 2023

New technologies, for digitizing economic entities, specific to the concept of Industry 4.0 cannot be put into practice without the use of numerically controlled equipment. Industrial Robots (IR) represent the equipment through the action programmed in the virtual environment is transferred in the real environment. In this case, the accuracy of the virtual model of a production system is essential. Practically, the "digital twin" of each real equipment, implicitly of RI, must be recreated. This paper aims to present the methodology for implementing IR in a CAD-CAM environments and its use in production system modeling applications. A digital twin IR definition consist in a correct modeling of robot features like architecture, controller, and kinematics.
NEW TECHNOLOGIES FOR THE STUDY AND MONITORING OF LANDSLIDES AFFECTING CRITICAL TRANSPORT INFRASTRUCTURE
Authors:   Fad Smart Technology SRL, CIOCAN Dorin-Cosmin ,   University of Bucharest, Faculty of Geology and Geophysics, Romania, PENEOAŞU Cristian-Ionuţ ,   Fad Smart Technology SRL; University of Bucharest, Faculty of Geology and Geophysics, FILIP Florin ,   Fad Smart Technology SRL; University of Bucharest, Faculty of Geography, Romania, BUDILEANU Marius ,   Fad Smart Technology SRL; University of Bucharest, Faculty of Geology and Geophysics, AVRAM Ovidiu ,   Fad Smart Technology SRL; Geological Institute of Romania, RUSU Emil ,   Fad Smart Technology SRL; Geological Institute of Romania
Published: February 2023

Landslide monitoring is becoming increasingly important for mitigating and eliminating risks to critical infrastructure (roads and highways, railways, waterways, energy transmission networks, etc.).This work aims to present the technique of electrical resistivity tomography (ERT) for the analysis and monitoring of landslides in conjunction with radar satellite data, InSAR (Interferometry for Synthetic Aperture Radar).The ERT and InSAR methods are complemented by the methods of automatic continuous monitoring during the execution and in the exploration of critical structures and infrastructures by introducing the real-time warning component of the events in progress. By applying these modern techniques, it is possible to reduce the geotechnical risk in the design phase, it is possible to reduce the construction and operation costs, but also to avoid losses due to landslides that can short-circuit critical transport infrastructures.
COLORS ANALYSIS AND TECHNOLOGICAL ERRORS IDENTIFIED IN PRINTING OF ROMANIAN POSTAL STAMPS
Authors:   Faculty of Industrial Engineering and Robotics, Robots and Production Systems Department, University POLITEHNICA of Bucharest, Romania, Păunescu Mihai , MaruŞciac Mihai ,   Doctoral School of Faculty of Automatics and Computer Science, Technical University of Cluj-Napoca, Romania, BăLAN Emilia ,   Faculty of Industrial Engineering and Robotics, Robots and Production Systems Department, University POLITEHNICA of Bucharest, Romania
Published: February 2023

Papers of value such as banknotes, stamps, stocks etc. are typographical products which are executed using special technologies which should ensure their protection against forgery. In order to verify their security elements, a digital comparative instrument has been designed and manufactured. This contains two digital microscopes mounted in parallel which can move simultaneously on the Oz axis and an adjustable and graded support for positioning the samples on the Ox and the Oy axes. The microscopes are calibrated from an optical and spectral standpoint at the beginning of the study based on the imposed tolerances. The visual field of the microscopes is illuminated in a controlled manner according to a standard light source, to properly ensure the correctness and consistency of the measurements. In this article, the experimental devise is used to record and analyze comparatively the colors and dimensions of the Romanian postal stamps to identify the technological printing errors.
NUMERICAL COMPUTATIONS OF THE CAVITY FLOWS USING THE POTENTIAL FLOW THEORY
Authors:   Dept. of Mechanical Engineering, Georgia Southern University, Statesboro, GA 30458, USA, ILIE Marcel , Semenescu Augustin ,   Dept. of Material Sciences, University Politehnica Bucharest, Bucharest, Romania, STROE Gabriela Liliana ,   Department of Aeronautical Systems Engineering and Aeronautical Management ”Nicolae Tipei”, University Politehnica Bucharest, Bucharest, Romania, BERBENTE Sorin ,   Department of Aeronautical Systems Engineering and Aeronautical Management ”Nicolae Tipei”, University Politehnica Bucharest, Bucharest, Romania
Published: February 2023

Computational fluid dynamics of turbulent flows requires large computational resources or are not suitable for the computations of transient flows. Therefore methods such as Reynolds-averaged Navier-Stokes equations are not suitable for the computation of transient flows. The direct numerical simulation provides the most accurate solution, but it is not suitable for high-Reynolds number flows. Large-eddy simulation (LES) approach is computationally less demanding than the DNS but still computationally expensive. Therefore, alternative computational methods must be sought. This research concerns the modelling of inviscid incompressible cavity flow using the potential flow. The numerical methods employed the finite differences approach. The time and space discretization is achieved using second-order schemes. The studies reveal that the finite differences approach is a computationally efficient approach and large computations can be performed on a single computer. The analysis of the flow physics reveals the presence of the recirculation region inside the cavity as well at the corners of the cavity
A COMPUTATIONAL COMBUSTION METHOD FOR TURBULENT PULVERIZED SOLID FUEL USING LES
Authors:   Dept. of Mechanical Engineering, Georgia Southern University, Statesboro, GA 30458, USA, ILIE Marcel , Semenescu Augustin ,   Dept. of Material Sciences, University Politehnica Bucharest, Bucharest, Romania, STROE Gabriela Liliana ,   Department of Aeronautical Systems Engineering and Aeronautical Management ”Nicolae Tipei”, University Politehnica Bucharest, Bucharest, Romania, BERBENTE Sorin ,   Department of Aeronautical Systems Engineering and Aeronautical Management ”Nicolae Tipei”, University Politehnica Bucharest, Bucharest, Romania
Published: February 2023

The solid fuels are still used in many regions of the world and assures the energy production. Nowadays, the mitigation of climate changes require strict regulations regarding the use and efficient combustion of solid fuels such as coal and reduction of the emissions. One way to ensure reduction of the emissions is an efficient combustion, which can be obtained using the pulverized coal. The pulverized coal ensure the good mixing of the fuel and air reactants and thus, it ensures an efficient combustion and minimization of the emissions. Experimental studies of solid fuels combustion are challenging and costly. Therefore, the computational methods offer the advantage of fast and accurate predictions of the flow variables and combustion products. In this study we propose a computational method using the large-eddy simulation (LES) approach along with the flamet combustion model. The study shows that the LES approach along with the flamet model predict very well the flow variables and combustion products. The study reveals an increase of entropy and decrease of density in the combustion region. As the flame moves towards the exit of the combustion the temperature decreases.
COMPUTATIONAL STUDIES OF AEROELASTICITY OF AIRCRAFT ENGINE TURBINE BLADE
Authors:   PhD, Assistant Professor: Dept. of Mechanical Engineering, Georgia Southern University, Statesboro, GA 30458, USA. E-mail: milie@georgiasouthern.edu, ILIE Marcel , SEMENESCU Augustin ,   PhD, Professor, Dept. of Material Sciences, University Politehnica Bucharest, Bucharest, Romania; Associate Member of Academy of Romanian Scientists. E-mail: augustin.semenescu@upb.ro
Published: February 2023

Transient blade loading limits the lifetime of aircraft engine turbine blades. Thus, accurate prediction of the unsteady aerodynamic loading and coupled fluid-structure interactions would improve the life the lifetime of the turbine blades. This study investigates the flutter instability of an axial turbine blade under unsteady aerodynamic loading. The viscous Navier-Stokes equations with the SST-kω turbulence model are employed. The results show that the flutter phenomenon causes unsteady oscillations of the aerodynamic coefficients lift and drag.
SIMULATION OF STRAIN DISTRIBUTIONS FOR PLANE STRAIN TENSILE TEST USING DC05 COLD ROLLED STEEL
Authors:   PhD, Raid Fekhreddine Meknassi, University of Miskolc, Faculty of Mechanical engineering, Miskolc, Hungary, (raidrawda@gmail.com)., MEKNASSI Raid-Fekhreddine , BÉRES József-Gábor ,   Dr, Gábor József Béres, John von Neumann University, GAMF Faculty of Engineering and Computer Science, Kecskemét, Hungary, (beres.gabor@gamf.uni-neumann.hu)., ZSOLT Lukács ,   Dr, Lukács Zsolt University of Miskolc, Faculty of Mechanical engineering, Miskolc, Hungary, (metzsolt@uni-miskolc.hu).
Published: February 2023

Material prediction behavior in the sheet metal forming operations is one of the critical fields of this process, especially for the industry and sheet metal forming processes in more precisely. Knowing the material behavior is a must to ensure the accuracy during the prediction for the best final size and shape. In this work we made a numerical investigation using a finite element software ABAQUS, of a plane strain tensile test for a DC05 cold rolled steel with different specimen geometry, to investigate the effect of different geometries on the strain distributions.
Forensic Science or Forensic Sciences? Conceptual analysis
Authors: Rodrigues Caio Henrique Pinke , Amaral Maria Eduarda Azambuja , Mariotto Lívia Salviano , Castro Jade Simões , Mascarelli Marina Enriquetto , Velho Jesus Antônio , Bruni Aline Thais
Published: February 2023

Science and justice need to interact to solve different situations. This interaction, however, needs to occur efficiently to avoid generating even more doubts. Scientific evaluation in the legal context must be understood and achieve its purpose. For this, much has been discussed about the nature and purpose of forensic scientific assessment. In this work, the aim was to evaluate what forensic science is and what is the conceptual alignment of this area of knowledge concerning national and international scenarios. We performed a bibliographic review on the subject to understand the fundamental aspects of this theme. Conceptual studies on forensic science are practically non-existent in the national literature. Forensic science was contextualized in its multi, inter, and transdisciplinary aspects. The quantitative results of the bibliographic review showed the urgent need for developing the theme in the national scenario and its alignment with the world understanding. Historical aspects of the development of forensic science were used in the discussion about the conceptualization of the term. Yet, internationally there are constant efforts to define the purpose and scope of forensic science. The Sydney Declaration was recently launched as a guiding document. We concluded that discussion about the concept of forensic science must be constant to improve it at the national level and to align it with international thinking. Hopefully, this work will encourage the discussion of the topic, strengthening the development of forensic science and reinforcing its importance for the administration of justice.
Validation and the Reliability of the ACIC Questionnaire in the Primary Health Care Setting
Authors: Pilipovic-Broceta Natasa , Vasiljevic Nadja , Todorovic Nevena , Racic Maja
Published: February 2023

Objective. The aim of this study was to carry out the cultural adaptation and validation of the Assessment of Chronic Illness Care questionnaire (ACIC) in the Republika Srpska, Bosnia and Herzegovina.

Methods. A validation study was conducted in two randomly selected primary health care centers in the Republika Srpska, Bosnia and Herzegovina, during March and April 2016. The study participants were all physicians working in family medicine departments during the study. Translation of the ACIC questionnaire version 3.5 was performed following the guidelines of the World Health Organization. The validity and reliability of the questionnaire were tested with face validity, construct validity, and internal consistency.

Results. The questionnaire was distributed to 66 family physicians. Missing values were negligible, therefore the criteria for factor analysis were met. Exploratory factor analysis confirmed that the questionnaire measured one factor. The Cronbach alpha coefficient (0.970) showed the excellent level of internal consistency of the questionnaire. The intraclass correlation coefficient (0.802) confirmed the good reliability of the questionnaire.

Conclusion. The ACIC questionnaire can be used to assess the quality of chronic care in family medicine practice in Bosnia and Herzegovina. Further research is needed to explore how changes in healthcare care delivery impact changes in the Chronic Care Model domain.
A Hypertrophic Anterior Scalene Muscle and the Passage of a Subclavian Artery Through its Fibres: The Location of Possible Entrapment
Authors: Tsakotos George , Karampelias Vasilios , Chatziandreou Ilenia , Philippou Dimitrios , Totlis Trifon , Piagkou Maria
Published: February 2023

Objective. The presence of cervical ribs, 1st rib anomalies, cervical muscle hypertrophy and repetitive motion are possible aetiologies of subclavian artery (SCA) entrapment and/or compression. Thoracic outlet syndrome of the arterial type may appear with symptoms of hand pain due to the aneurismal part of the compressed SCA. The current cadaveric case describes a hypertrophic right-sided anterior scalene muscle (ASM) and the possible entrapment of the right SCA (RSCA) passing through its fibres. Furthermore, the branching pattern of the entrapped vessel is analysed.

Case Report. A hypertrophic ASM was identified in the right infraclavicular area of a male Greek donated cadaver (70 years of age). The RSCA passed through the ASM belly, and some deeply situated fibres extended posteriorly to the RSCA. The ASM compressed the RSCA against the superior part of the 1st rib.

Conclusion. Knowledge of such variants may be important in the diagnosis of upper limb muscle atrophy or neurosensory loss.
Analysis of siRNA with Denaturing and Non-Denaturing Ion-Pair Reversed-Phase Liquid Chromatography Methods
Authors: Yogendrarajah Pratheeba , Suarez Marina Irene , Verluyten Willy , Dejaegere Evelien , Napoletano Leslie , Boon Jean-Paul , Hellings Mario , Gilar Martin
Published: February 2023

In this paper, we describe denaturing and non-denaturing ion-pair reversed-phase liquid chromatography (RPLC) methods for analyzing small interfering ribonucleic acid (siRNA). Drug formulations consisting of one or two siRNA duplexes were analyzed in non-denaturing conditions at a low column temperature to separate intact duplexes from single-stranded oligonucleotide contaminants and quantify them. In a denaturing method, we used an elevated column temperature to ensure the denaturation of siRNA duplexes into their single-stranded oligonucleotide counterparts. The goal of the denaturing LC method was to investigate the impurities in daughter oligonucleotides in siRNA. A column with chemically modified C18 column hardware showed improvements in analytical performance for nucleic acids compared to a conventional C18 stainless-steel column with the same pore size.