bluuebunny/crossref_metadata_2025 huggingface dataset:
Serological Comparison of Native Antigen ELISAs with Rapid ICT Test Kits for the Diagnosis of Human Alveolar and Cystic Echinococcosis in China
Authors: Yang Shu-Kun , Zhang Wei , Zhu Na , McManus Donald P. , Gray Darren J. , Clements Archie C. A. , Cadavid Restrepo Angela M. , Williams Gail M. , Zhang Ting , Ma Guo-Rong , Yang Yan-Hui , Yang Yu-Rong
Published: February 2024

Background: The aim of this study was to compare the diagnostic performance of native antigen ELISAs and ADAMU-AE/CE commercial ICT test kits in subjects either exposed to Echinococcus infection or with clinically diagnosed alveolar (AE) or cystic (CE) echinococcosis. Methods: A total of 370 subjects with a previous clinical confirmation of CE or AE from northwestern China were recruited. Serum samples were also obtained from 3923 children/teenagers during a community survey. All sera were tested using native antigen ELISAs. The ADAMU-AE/CE test kits were subsequently used for the serology of the 370 clinically confirmed individuals and of 251 children/teenagers that were ELISA antibody-positive for both Echinococcus species but ultrasound-negative during baseline survey. An analysis of the association between the serological tests and ultrasound classification was carried out amongst 89 AE and 164 CE cases. A Kappa consistency analysis was undertaken to compare the diagnostic performance of the native antigen ELISAs and the ADAMU kits and the ultrasound imaging results. The χ² test was also used for a comparison of the different seropositivity rates between the groups. Findings: There was poor consistency (Kappa = 0.26 and 0.28 for AE and CE respectively) between the native antigen ELISAs and the ADAMU kits for the diagnosis of AE and CE among the cases and the surveyed children/teenagers, but a relatively good consistency (Kappa = 0.63) between the ADAMU-AE kit and ultrasound observations for the AE cases. Additionally, of the 251 teenagers co-positive for both AE and CE antibodies by the native antigen ELISAs, only one was found positive by the ADAMU-AE kit, verified as a new AE case on subsequent ultrasound follow-up. The remainder (N = 250) were negative by serology using the ADAMU-AE/CE kits and by ultrasound examination. The two native antigen ELISAs did not discriminate well between cases of clinically diagnosed AE and CE. In contrast, ADAMU-AE and ADAMU-CE commercial ICT test kits readily differentiated cases of AE from CE with specificities of 99% for AE and 100% for CE. Conclusions: The ADAMU-AE/CE kits proved reliable, accurate, and amenable diagnostic tools in the clinical setting for confirmation of suspected AE/CE cases. The native antigen ELISAs tests can provide useful information on the level of human exposure to Echinococcus infection.
Status of Routine Immunization Coverage in the World Health Organization African Region Three Years into the COVID-19 Pandemic
Authors: Mboussou Franck , Kada Sarah , Danovaro-Holliday Maria Carolina , Farham Bridget , Gacic-Dobo Marta , Shearer Jessica C. , Bwaka Ado , Amani Adidja , Ngom Roland , Vuo-Masembe Yolande , Wiysonge Charles Shey , Impouma Benido
Published: February 2024

Data from the WHO and UNICEF Estimates of National Immunization Coverage (WUENIC) 2022 revision were analyzed to assess the status of routine immunization in the WHO African Region disrupted by the COVID-19 pandemic. In 2022, coverage for the first and third doses of the diphtheria–tetanus–pertussis-containing vaccine (DTP1 and DTP3, respectively) and the first dose of the measles-containing vaccine (MCV1) in the region was estimated at 80%, 72% and 69%, respectively (all below the 2019 level). Only 13 of the 47 countries (28%) achieved the global target coverage of 90% or above with DTP3 in 2022. From 2019 to 2022, 28.7 million zero-dose children were recorded (19.0% of the target population). Ten countries in the region accounted for 80.3% of all zero-dose children, including the four most populated countries. Reported administrative coverage greater than WUENIC-reported coverage was found in 19 countries, highlighting routine immunization data quality issues. The WHO African Region has not yet recovered from COVID-19 disruptions to routine immunization. It is critical for governments to ensure that processes are in place to prioritize investments for restoring immunization services, catching up on the vaccination of zero-dose and under-vaccinated children and improving data quality.
Correlating Stability-Indicating Biochemical and Biophysical Characteristics with In Vitro Cell Potency in mRNA LNP Vaccine
Authors: Tong Xin , Raffaele Jessica , Feller Katrina , Dornadula Geethanjali , Devlin James , Boyd David , Loughney John W. , Shanter Jon , Rustandi Richard R.
Published: February 2024

The development of mRNA vaccines has increased rapidly since the COVID-19 pandemic. As one of the critical attributes, understanding mRNA lipid nanoparticle (LNP) stability is critical in the vaccine product development. However, the correlation between LNPs’ physiochemical characteristics and their potency still remains unclear. The lack of regulatory guidance on the specifications for mRNA LNPs is also partially due to this underexplored relationship. In this study, we performed a three-month stability study of heat-stressed mRNA LNP samples. The mRNA LNP samples were analyzed for their mRNA degradation, LNP particle sizes, and mRNA encapsulation efficiency. In vitro cell potency was also evaluated and correlated with these above-mentioned physiochemical characterizations. The mRNA degradation–cell potency correlation data showed two distinct regions, indicating a critical cut-off size limit for mRNA degradation. The same temperature dependence was also observed in the LNP size–cell potency correlation.
MV130 in the Prevention of Recurrent Respiratory Tract Infections: A Retrospective Real-World Study in Children and Adults
Authors: Montalbán-Hernández Karla , Cogollo-García Ana , Girón de Velasco-Sada Patricia , Caballero Raquel , Casanovas Miguel , Subiza José Luis , Conejero Laura
Published: February 2024

Respiratory tract infections (RTIs) are among the most common and important problems in clinical medicine, making antibiotics the gold standard therapeutic option regardless of their frequent viral etiology. Their excessive and inappropriate use contributes to the rapid rise of antibiotic resistance and underscores the need for alternative strategies, especially when dealing with recurrent RTIs. Prevention is the ideal alternative, but specific vaccines targeting a wide range of respiratory pathogens are scarce. MV130 is a sublingual bacterial vaccine that induces trained immunity and provides non-specific protection against respiratory pathogens in various clinical settings according to the concept of TIbV (Trained Immunity-based Vaccine). A retrospective real-world study (RWS) was conducted to evaluate the annual incidence of RTIs and the consumption of antibiotics before and after the administration of MV130, using data sourced from the medical records of 599 patients (186 children and 413 adults) who suffered from recurrent RTIs. The median number of infectious episodes in children was significantly reduced by more than 70% from 5 episodes (interquartile range (IQR) 4.0–6.0) to 1 (IQR, 0.0–2.0) (p < 0.001) after MV130. Similarly, in adults, the median number of episodes before MV130 immunization was 5 (IQR, 4.0–6.0), which dropped by more than 80% to 1 (IQR, 0.0–1.0) during the year following MV130 immunization (p < 0.001). The median number of antibiotic courses also significantly decreased for both children and adults by over 80% (p < 0.001). This RWS showed that MV130 is an effective strategy for the prevention of respiratory infections and the reduction of associated antibiotic consumption.
Experiences of Parents of Trans and Non-Binary Children Living in the Region of Quebec
Authors: Ladry Naomie-Jade , Pullen Sansfaçon Annie , Dyer Jennifer
Published: February 2024

The coming out process differs for everyone, and parents may experience difficulties such as external stress, ostracism and finding local services. Access to resources is, therefore, fundamental, and parents need support in accompanying their children. Methods: This research was carried out in two waves. Firstly, data collection began with parents of TNB children living in the Gaspésie, Bas-Saint-Laurent and Îles-de-la-Madeleine regions, who participated in five group meetings. Secondly, nine in-depth interviews were conducted with parents living in the province of Quebec, outside major urban centres. Results: This article presents the synergy between the two waves of data collection. The results show that parents report various experiences of vulnerability in the process of accepting their children’s gender identity. Despite this, the families we met provided their children with unconditional support to help them navigate various service structures. Conclusions: Although parents of TNB children living in regional areas face similar difficulties to their urban peers, the lack of resources and access to services limits their options, contributing to their isolation. As a result, these parents must employ strategies to initiate change and improve their conditions.
Trophic position and niche overlap of an Asian weatherfish (Misgurnus bipartitus), western tubenose goby (Proterorhinus semilunaris) and native benthic fish species
Authors: Lemmers Pim , Olde Wolbers Robin , van der Velde Gerard , Leuven Rob S. E. W.
Published: February 2024

Co-occurring and morphologically similar species have adapted to differential niches to minimize competition. An invasive alien species can occupy an ‘empty niche’ in introduced ranges. Alternatively, the invader may occupy an overlapping niche and compete with native species to a certain degree. In a Western European lowland brook with high nutrient loads, we studied a benthic community of five fish species, including two alien species: an Asian weatherfish (Misgurnus bipartitus) and the western tubenose goby (Proterorhinus semilunaris). The native species concerned stone loach (Barbatula barbatula), spined loach (Cobitis taenia), and gudgeon (Gobio gobio). Because of the unknown effects of the invaders on native benthic fish species, the trophic position, isotopic niche overlap, and potential food competition among these species were identified using nitrogen and carbon stable isotopes. The trophic levels of the five fish species indicated that they are secondary consumers. The body size of native fish species correlated significantly negatively with their δ15N (‰) signature, in contrast with the invaders indicating that the latter are generalists. Significant isotopic niche overlap was observed among all benthic species. The degree of niche overlap of M. bipartitus was the highest with G. gobio (91.8%). Proterorhinus semilunaris showed the highest degree of niche overlap with B. barbatula (91.2%). It was notable that the observed niche overlap between the native B. barbatula and C. taenia was high (99.2%). Overlap between M. bipartitus and P. semilunaris was low (8.9%), indicating little resource competition between these alien species. Native species showed wider isotopic niches than the invaders. Bayesian mixing models revealed that native and alien species slightly differ in their main diet. The results suggest that the invaders are plastic in their resource use, leading to niche differentiation and promoting the co-existence of benthic fish species.
Features of investigative actions when investigating crimes related to land damage
Authors:   Department of Public Law, Federal State Educational Institution of Higher Education ", Blankov A. S. ,   State University of Land Management",   , Moscow, Vinogradova O. B. ,   Department of Public Law, Federal State Educational Institution of Higher Education "State University of Land Management", Moscow, Orlova Yu. R. ,   Department of Public Law, Federal State Educational Institution of Higher Education "State University of Land Management", Moscow
Published: February 2024

The article examines various types of crimes associated with violation of environmental norms, destruction of vegetation, or improper use of land resources. The authors analyze the challenges that arise during the investigation process, and offer practical recommendations for optimizing related activities. The study is based on the analysis of court practices, existing legislation, and expert opinions.
Visualising the South English Legendaries: Dataset (2024)
Authors: Taylor Tristan B , Dase Kyle
Published: February 2024

The South English Legendaries are collections of thirteenth-century sanctorale and temporale that circulated widely between the thirteenth and sixteenth centuries. These collections have a complex textual history, and scholars have spent the last century attempting to develop a textual history for the collections that explain the variations found in both the collocation and mouvance. Manfred Görlach, in his 1974 publication, The Textual Development of the South English Legendary, provides the foundations for much of our understanding of the relationships between the different manuscript witnesses. In this work, he provides several different visualisations of the collection, including a stemma, maps of the geographical and dialectic, and tables of legend arrangements. This dataset, built on Görlach’s seminal work, amends errors of omission and commission by adding newly discovered manuscripts now catalogued on the Digital Index of Medieval Verse. This dataset can be manipulated in software like Gephi to visualise the networks that emerge from the relationships between the different legends and their corresponding manuscripts. This dataset is part of an ongoing “Un-editing the South English Legendaries” project, which will produce a digital variorum of the SEL.
A Social Network Analysis of Hemodialysis Clinics: Attitudes Toward Living Donor Kidney Transplant among Influential Patients
Authors: Calvelli Hannah , Gardiner Heather , Gadegbeku Crystal , Reese Peter , Obradovic Zoran , Fink Edward , Gillespie Avrum
Published: February 2024

Key Points

Hemodialysis clinic social networks spread attitudes and behaviors toward kidney transplants.

Identifying and characterizing influential patients is a first step in future hemodialysis clinic social network interventions to promote kidney transplantation.

Background

Hemodialysis clinics help develop patient social networks that may spread kidney transplant (KT) attitudes and behaviors. Identifying influential social network members is an important first step to increase KT rates. We mapped the social networks of two hemodialysis facilities to identify which patients were influential using in-degree centrality as a proxy for popularity and influence.

Methods

In this cross-sectional study, we performed a sociocentric social network analysis of patients on hemodialysis in two geographically and demographically different hemodialysis facilities. Statistical and social network analyses were performed using R statistical software.

Results

More patients at facility 1 (N=71) were waitlisted/evaluating living donor KT (50.7% versus 20.0%, P = 0.021), considered KT as very important (70.4% versus 45.0%, P = 0.019), and knew people who received a successful KT (1.0 versus 0.0, P = 0.003). Variables predicting relationship formation at facility 1 were the same shift (β=1.87, 95% confidence interval [CI] [1.19 to 2.55]; P < 0.0001), same sex (β=0.51, 95% CI [0.01 to 1.00]; P = 0.045), younger age (β=−0.03, 95% CI [−0.05 to −0.01]; P = 0.004), different lengths of time on hemodialysis (β=−0.49, 95% CI [−0.86 to −0.12]; P = 0.009), and knowing more people who received a successful KT (β=0.12, 95% CI [0.03 to 0.21]; P = 0.009). Predictive variables at facility 2 (N=40) were the same race (β=2.52, 95% CI [0.39 to 4.65]; P = 0.021) and knowing fewer people with successful KT (β=−0.92, 95% CI [−1.82 to −0.02]; P = 0.045). In-degree centrality was higher at facility 1 (1.1±1.2) compared with facility 2 (0.6±0.9).

Conclusions

Social networks differed between the hemodialysis clinics in structure and prevalent transplant attitudes. Influential patients at facility 1 (measured by in-degree centrality) had positive attitudes toward KT, whereas influential patients at facility 2 had negative attitudes.
Reconceptualizing Job Satisfaction in Trinidad and Tobago
Authors: Young Andrew Christopher
Published: February 2024

The current research explores the latent drivers of job satisfaction in Trinidad and Tobago. The aim is to determine the construct validity of the Hackman Oldham (1975) Job Characteristics Model (JCM) to measure job satisfaction. Data was collected from employees using the cross-sectional research method and conveniently sampled from twelve (12) service institutions.The twelve (12) service institutions span three sectors: information and communications technology (ICT), tertiary education, and public utilities. These three (3) sectors were chosen because they represent the three most significant sectors in the Trinidad and Tobago economy and three (3) different levels of industry. Using three (3) different sectors in research enhances generaliz ability by providing a more diverse sample, reducing the risk of bias, and increasing the likelihood that findings can be applied to a broader range of contexts or populations. The service institutions include TSTT, FLOW, and DIGICEL (Information and Communications Technology). UTT, UWI, SBCS, ALJ-GSB, SAMS-TT, and CTS-CBS (Leaders in Tertiary Education). WASA, T&TEC, and PTSC (Public Utilities).
Optimizing Returns: A Holistic Financial Model for Off-Grid Glamping Ventures
Authors: Whitfield Richard , Juffermans Leon , Dean Paul , Noordzy Gert
Published: February 2024

Glamping is becoming increasingly popular and may yield better financial returns than traditional hotel developments in some situations, especially in unspoiled locations which are inaccessible for traditional hotel/resort construction because it disturbs the site too much. This paper presents a detailed financial model for analysing the performance of glamping properties to inform decision-making about investing in them.
It focuses particularly on properties that are “off the beaten track” for singles, couples, small families and others who want to “unwind” and “commune with nature” in relatively isolated off-grid locations, such as nature reserves, vineyard/wineries, golf resorts or wellness and spa hideaways. In the authors’ view, glamping is particularly well suited to this kind of hotel.
In the normal way, the financial model summarizes the development of these properties in detail and itemizes the specific capital investments needed to establish an off-grid glamping property, in contrast to a similar traditional grid-connected hotel.
Group B Streptococcus as a Cause of Intrauterine Infections
Authors: Логинова О.П. , Шевченко Н.И.
Published: February 2024

Стрептококк группы В является значимым агентом в этиологии внутриутробной инфекции среди новорожденных детей. Расширение диагностических возможностей, появление и увеличение количества резистентных штаммов возбудителей требует осуществления постоянного мониторинга резистентности стрептококка группы В, что позволит усовершенствовать терапевтические подходы и предупредить неблагоприятные последствия.

Group B Streptococcus is a significant agent in the etiology of intrauterine infection among newborns. The expansion of diagnostic capabilities, the emergence and increase in the number of resistant strains of pathogens requires constant monitoring of the resistance of group B streptococcus, which will improve therapeutic approaches and prevent adverse consequences.
Traversing the Digital Era: The Amazing Evolution of Pen and Paper to Screens and Keyboards
Authors: Eslit Edgar R.
Published: February 2024

In this research article, the researcher delves into the ebb and flow of human ingenuity as the paper traces the evolution of writing from papyrus to pixels.  Discover how humble instruments like quill pens and typewriters have propelled human into the digital frontier, forever reshaping the art of expression in the modern age. This article examines the evolution of writing tools from traditional pen and paper to digital writing in the modern age. It explores the development of writing materials such as papyrus, parchment, and paper, as well as the invention of writing tools including quill pens, fountain pens, and typewriters. The rise of digital writing tools, including word processing software and smartphones, is also discussed, along with their benefits such as increased efficiency and productivity, enhanced collaboration and sharing capabilities, and greater accessibility and flexibility. However, the article also highlights the challenges of writing in the digital age, including the impact of digital distractions on writing focus and quality, the issue of online plagiarism and copyright infringement, and the potential loss of traditional writing skills. The article concludes with recommendations for educators, school administrators, students, and researchers to strike a balance between digital and traditional writing practices, to embrace digital writing tools while preserving traditional writing skills, and to understand the importance of the evolution of writing. The theoretical frameworks of Social Construction of Technology (SCOT) Theory, Media Ecology Theory, and Activity Theory are also discussed in relation to the evolution of writing tools. Overall, this article provides valuable insights into the history, benefits, and challenges of writing in the digital age, as well as suggestions for navigating the future of writing and its tools.
Investigating The Influence of Teacher Aggression on Student Academic Motivation in Province of Sindh, Pakistan
Authors: Ahmed Maroof , Soomro Aizaz Ali , Haleema Haleema
Published: February 2024

The present study aimed to explore the impact of teacher aggressive behaviors on student academic motivation in Sindh, one of the provinces in Pakistan. A descriptive survey research design was employed, utilizing a sample of 120 public school teachers (70 female and 50 male). Data was collected using a researcher-developed instrument called the "Teachers Aggressive Behavior Survey" (TABS). The research questions were answered using descriptive statistics, including means and standard deviations, and the hypothesis was tested using t-test statistics at a significance level of 0.05. The results indicated that teachers exhibit various forms of aggressive behaviors that negatively impact student participation in academic activities. It is recommended that school administrators take steps to raise awareness among teachers about the detrimental effects of aggressive behaviors on student academic motivation.
Respon Pemberian Pupuk Petroganik Terhadap Pertumbuhan Dan Produksi Beberapa Varietas Tanaman Mentimun (Cucumis sativus l.) Di Desa Besar II Terjun Serdang Bedagai
Authors: Andini Anggi , Samah Eri , Mufriah Dini
Published: February 2024

In this research, we wanted to see the response of applying petroganic fertilizer to the growth and production of several varieties of cucumber (Cucumis sativus L.) in Besar II village, Terjun Serdang Bedagai. The study was conducted by a factorial Randomized Block Design (RBD), with two factors namely: Petroganic Fertilizer Factor (P) with 4 levels, namely: P0= 0 kg/plot (Control), P1= 0.5 tons/ha (50 gram/plot), P2= 1 ton/ha (100 gram/plot) (recommended dose), P3= 1.5 ton/ha (150 gram/plot), Cucumber Variety Factor (V) with 2 levels, namely V1= Harmoni Plus, V2= Monas F1. The growth of cucumber plants due to petroganic fertilizers showed a significant effect on plant height, stem diameter at plant ages 15, 30 and 45 days after planting, fruit length at 45 and 50 days after planting, fruit weight at 40, 45 and 50 days after planting. Petroganic fertilizer had no significant effect on fruit length 40 days after planting. The best petroganic fertilizer treatment is P3 which is 150 gram/plot. The growth of cucumber plants due to the variety treatment showed no significant effect on all parameters, namely plant height and stem diameter at the age of 15, 30 and 45 days after planting and fruit length and fruit weight at 40, 45 and 50 days after planting. The best variety treatment was V2, namely the Monas F1 variety. The interaction between the petroganic fertilizer treatment and the variety treatment had no significant effect on all observed parameters.
Induksi Tunas Beberapa Varietas Nilam (Pogostemon cablin Benth.) dan Konsentrasi BAP Secara In Vitro Shoot Induction of Several Varieties of Patchouli (Pogostemon cablin Benth.) and Concentration of BAP In Vitro
Authors: Amalia Firda , Basyah Bakhtiar , Kesumawati Elly
Published: February 2024

Conventional propagation of patchouli plants has not met the demand for superior seeds. Propagation of superior seeds in a relatively short time can be done using in vitro culture techniques. This research aims to determine the induction of patchouli shoots of Tapaktuan, Lhokseumawe and Sidikalang varieties with Benzyl Amino Purine (BAP) concentrations in vitro. This research was carried out at the Plant Tissue Culture Laboratory, Faculty of Agriculture, Syiah Kuala University. This research used a Randomized Block Design with a 3x4 factorial pattern consisting of 2 factors. The first factor was patchouli variety which consisted of 3 levels, namely: Tapaktuan, Lhokseumawe, and Sidikalang. The second factor was BAP concentration which consisted of 4 levels, namely: 0 (control), 0.5, 1, and 1.5 mg L-1. The results showed that the percentage of live patchouli explants was 100% in all treatments. The time and percentage of shoot emergence tended to be faster in the Lhokseumawe + BAP 0.5 mgL-1, namely 17.5 days after planting (DAP) and 100%. The number of patchouli explant shoots tended to be high in the Sidikalang + BAP 0.5 mgL-1, namely 12 shoots. The number of patchouli explant leaves tended to be high in the Lhokseumawe + BAP 1 mgL-1, namely 13 sheets. Patchouli explants tended to be taller in the Sidikalang + control, namely 8 cm. The percentage of callus formation tends to be high in the varieties Tapaktuan + BAP 1 mgL-1, Sidikalang + BAP 0.5 mgL-1, Sidikalang + BAP 1 mgL-1, Tapaktuan + BAP 1.5 mgL-1, Sidikalang + BAP 1.5 mgL-1 and Sidikalang + control were above 50% at 4 WAP. The number of patchouli explant roots tended to be high in the Tapaktuan + control, namely 16.50 roots.

Keywords: Aceh Patchouli, BAP, Cytokinin, Explant, Patchouli Shoots
Kepemimpinan dan Akuntabilitas Keuangan di Pemerintah Daerah
Authors: Haya Fran Giska Fadhiya , Abdullah Syukriy
Published: February 2024

This literature discusses about the relation between leadership and accountability in local government. Accountability can develop in a transparent and democratic manner as well as freedom in expressing opinions. Therefore, the government must really realize that government and services cannot be separated from the public. The realization of regional financial accountability will be the basis for better governance and the government can provide financial accountability from public funds managed by local governments in order to gain public trust. Regional financial accountability is the responsibility of local governments related to regional financial management for the welfare of the community openly and honestly through the media in the form of presenting financial reports. Leadership is one of the important aspects of the organization, especially in the scope of local government administration. In the recent period, leadership is required to focus more on how the role of leadership in an organization will have a positive impact on the organization. Local governments face great pressure in the implementation of regional autonomy. There are two important institutions in local government, namely DPRD and regional apparatus based on regional regulations. Accountability to local governments will grow when supported by an accountable work environment. The main element of the environment is leadership
Budaya Organisasi dan Penerapan Akuntansi di Pemerintah Daerah di Aceh
Authors: Shafira Cut Alya , Abdullah Syukriy
Published: February 2024

AbstractThis paper describes the relationship between organizational culture and the application of accounting in local government in Aceh. Aceh has a uniqueness and specificity that has implications for the implementation of government functions, such as: the existence of Islamic law, the acceptance of special autonomy funds and a long history as a great nation. Local governments in Aceh currently carry out public service and governance functions based on Law No. 11 of 2006 concerning the Government of Aceh, which does not apply in other areas. For this reason, several Regional Apparatus Work Units (SKPD) in Aceh do not exist in other provinces in Indonesia.Keywords: budaya organisasi, penerapan akuntansi, UU No. 11 Tahun 2006, satuan kerja perangkat daerah, syari’at Islam.
Tingkat Kepuasan Masyarakat Terhadap Kualitas Pelayanan Publik di Bagian Setdakab Aceh Singkil
Authors: Rahmita Nova , Irmalis Amsal
Published: February 2024

Tingkat kepuasan masyarakat terhadap kualitas pelayanan publik di bagian Setdakab Aceh Singkil adalah suatu hakikat dimana pemerintah Sekretariat Daerah Kabupataen (Setdakab) Aceh Singkil berhak memberikan pelayanan yang baik bagi masyarakat Aceh Singkil sesuai dengan Standar Operasional Pelayanan Publik, agar masyarakat merasakan kepuasan dari pelayanan yang ada di Setdakab Aceh Singkil. Penelitian ini bertujuan untuk mengetahui sejauh mana tingkat kepuasan masyarakat terhadap pelayanan publik., penelitian ini menggunakan metode kualitatif dengan menggunakan pendekatan studi kasus, dimana pengumpulan data menggunakan teknik observasi dan wawancara berupa kata-kata, tulisan atau lisan dari orang-orang atau pelaku yang di amati. Adapun tingkat kepuasan masyarakat terhadap kualitas pelayanan publik di Setdakab Aceh Singkil belum sepenuhnya bagus seperti yang diinginkan masyarakat Aceh Singkil.
Peningkatan Performance Pegawai di Sekretariat Daerah Kabupaten Aceh Selatan Melalui Motivation Dan Work Discipline
Authors: Hasmanidar Hasmanidar
Published: February 2024

Kinerja ( performance ) adalah hasil kualitas dan kuantitas kerja yang dicapai oleh seorang pegawai dalam melaksanakan tugasnya sesuai dengan tanggung jawab yang diberikan kepadanya, motivasi (motivation ) dan disiplin kerja (work dicipline ) merupakan faktor penting dalam  meningkatkan kinerja. Penelitian ini dilakukan di Kantor Sekretariat Daerah  yang berlokasi di Jl.T. Ben Mahmud No 11, Tapaktuan Aceh Selatan. Yang bertujuan untuk mengetahui pengaruh motivasi dan disiplin kerja terhadap peningkatan kinerja pegawai di kantor Setdakab baik secara parsial maupun simultan.Untuk mengoptimalkan kinerja pegawai menjadi kajian permasalahan dalam penelitian ini. Hasil penelitian ini diharapkan dapat memberikan tambahan informasi mengenai seberapa besar pengaruh motivasi dan disiplin kerja terhadap peningkatan kinerja pegawai Setdakab Aceh Selatan. Motede pengambilan data menggunakan kuesioner, observasi dan studi kepustakaan sesuai tujuan peneliti, populasi dalam penelitian ini berjumlah 187 pegawai dengan sampel yang telah di tetapkan melalui sampel acak sebanyak 64 pegawai. Dalam penelitian ini peneliti menggunakan metode kuantitatif yang bersifat assosiatif. Pengumpulan data menggunakan angket berupa pertanyaan, sumber data berasal dari data primer yang di peroleh langsung dari para responden. Pengkajian data menggunakan analisis regreasi linear berganda, Uji f dan Uji t. Hasil penelitian ini membuktikan bahwa motivasi dan disiplin kerja secara parsial maupun secara simultan mempunyai pengaruh positif dan signifikan terhadap kinerja pegawai pada Kantor Setdakab Aceh Selatan. Dengan hasil koefisien determinasi mampu menjelaskan bahwa pengaruh motivasi dan disiplin kerja terhadap kinerja pegawai sebesar 46,6% sisanya sebanyak 53,4% didapat dari faktor lain dan tidak diteliti pada model penelitian ini. Kata Kunci: Motivasi, Disiplin Kerja, Kinerja Pegawai
Analisis Dugaan Transaksi Mencurigakan Untuk Kepentingan Ilegal Pada Nasabah Bri Kcp Simpang Tiga Kota Pekanbaru
Authors: Wahyuningsih Endang Sri , Rodiah Siti
Published: February 2024

This study aims to determine the settlement of suspected suspicious transactions related to online gambling at BRI KCP Simpang Tiga. The problem studied is resolving customers suspected of carrying out suspicious transactions. Data were collected by interview and document recording; and analyzed using case study analysis with a qualitative approach. The results of the research show (1) customers provide different information to the bank; (2) customers who are suspected of making suspicious transactions, their account card must be immediately blocked so that irresponsible parties cannot misuse them; (3) if the accounts are not immediately closed or blocked, more people will be deceived; (4) before the account is blocked, the bank must confirm with the customer by visiting; and (5) the customer makes a statement. If something similar happens, the customer cannot open a new account at BRI. To avoid fraud related to online gambling transactions, customers should not easily give their accounts or personal data to others. To avoid being misused by irresponsible parties, customers must maintain data confidentiality, such as not providing usernames, passwords and OTP codes to any party, including family, friends, and the bank.
Penerimaan Teknologi Sistem OSS di DPMPTSP Kabupaten Nagan Raya
Authors: Febrianda Cut Enna
Published: February 2024

Information technology helps make the public service process much faster and more precise. The same service also forces service users to adapt to the computing and information programs offered by the service provider, making it easier for them to receive the services they want. OSS is a solution for licensing service users to get their services without attending the DPMPTSP office. This research wants to see how far service users can adapt to the OSS program and whether they feel comfortable with it. The results of the 73 research samples in this study showed that PU has a beta coefficient more significant than the PEOU variable in predicting attitudes towards using OSS. This means that the information system developed by the government has a high acceptance level because users must prioritize the usefulness of the system that has been developed from the previous system.
Analisis Pelaporan Keuangan Segmen Pada PT. Bayan Resources Tbk
Authors: Harahap Putri Dasti S , Fitriani Atika , Hasibuan Sarifah Aini , Wijaya Melki , Rodiah Siti
Published: February 2024

Companies that go public on average will definitely have financial reports, because to find out whether the company provides financial statement data tools that describe the company's performance in each period as a tool for making decisions and being accountable to related parties.  This report is made with the aim of making it easier for report users to see the total behind the consolidated figures to the individual components that make up the entity. One of the financial statements is a segment financial report. The segment financial report is a report that provides information data that is important enough to determine the company's performance in the form of profit contributions that grow in various geographic industrial areas. This research was taken from a sample of PT.Bayan Resources Tbk from the period 2018-2022 in accordance with PSAK number 5. PT.Bayan Resources Tbk has 2 segments, namely coal and non-coal segments. Data was collected through literal research techniques. Data analysis is done quantitatively.  The technique used is the Purposive Technique which is tested there is a revenue test, asset test and profit and loss test. The results of this study indicate that the segments at PT Bayan Resources Tbk in the profit and loss and asset tests have not met the 10% test in segment reporting.
Faktor-Faktor yang Mempengaruhi Produk Domestik Bruto (PDB) di Indonesia
Authors: Risma Okta Rabiana , Sari Yunidar Purnama , Ertika Yenny , Shifa Mutiara
Published: February 2024

The purpose of this research is to determine how the influence of money supply, inflation and interest rates on gross domestic product in Indonesia. This research is a quantitative research with multiple linear regression models. The data from 2000 to 2022 with Gross Domestic Product (GDP) as the dependent variable and the Money Supply, Inflation and Interest Rates as independent variables. The results  of this research is partially, the money supply and interest rates have a significant effect on gross domestic product, while inflation is not.  Then, simultaneously (together), the three variables have a significant effect on Gross Domestic Product (GDP).
Flipped classroom in financial accounting: analysis of student perception
Authors: Ciudad Gómez Adelaida
Published: February 2024

In Higher Education and in Financial Accounting, we have designed an educational innovation, within a comprehensive learning approach, through the use of the "flipped classroom" methodology, "blended learning", e-rubrics, collaborative learning and self-assessment / Peer evaluation, guiding us towards a formative and shared evaluation, being implemented in "Financial Accounting III" during the 2020-2021 and 2021-2022 academic years. The purpose of this work is, within a «Design-Based Research» strategy, to explore the perception and satisfaction of the student with the «flipped classroom» methodology and if it differs according to the student's gender, an experience in the classroom where they participated 67 students, with a non-probabilistic sample of 39 students who completed the questionnaire hosted on the Moodle platform, an instrument with a reliability level of α= .940 (Cronbach's Alpha). For the analysis and discussion of the results, measures of central position and dispersion have been used, together with the Mann Whitney U statistic, showing the results a positive perception of the students towards the adopted methodology, without significant differences depending on their gender, a finding that provides support to higher education financial accounting professors interested in using the flipped classroom.
История и юриспруденция мак̣а̄с̣ид
Authors: К АМАЛИ МОХАММАД ХАШИМ
Published: February 2024

Эта статья, которая первоначально была представ-лена в качестве пленарного доклада на симпозиуме«Американского журнала ислама и общества»«Теория и использование мак̣а̄с̣ид аш-шарӣ‘а» в мае2021 года, начинается с рассмотрения Корана и Сун-ны относительно мак̣а̄с̣ид, за ним следует анало-гичный обзор истории мак̣а̄с̣ид и выдающихся авто-ров, внесших вклад в их юриспруденцию, при этомобращается внимание на длительную маргинали-зацию мак̣а̄с̣ид в теории права. Далее рассматри-вается недавнее возрождение мак̣а̄с̣ид во второйполовине XX века, после чего следует примечаниеоб особой привлекательности мак̣а̄с̣ид, прекраще-нии исторического пренебрежения ими и значи-тельном возрождении интереса к ним со сторонысовременных мусульманских ученых. Отношениеус̣ӯл ал-фик̣х к мак̣а̄с̣ид также стало предметомвозобновленного интереса в отношении того, яв-ляется ли оно отношением продолжающегося гос-подства или взаимодополняемости. Затем следуетраздел, посвященный классификации мак̣а̄с̣ид,тому, как они оцениваются и расставляются в по-рядке приоритета относительно друг друга; и обзорметодологических показателей, которые могут по-мочь в оценке и ранжировании мак̣а̄с̣ид и их приме-нении к новым вопросам. Статья завершается опи-санием иджтиха̄да мак̣а̄с̣иди и его применения ксовременным проблемам.
Surgical treatment of the knee joint for chondral defects and a new approach to the role and place of mosaic autochondroplasty
Authors: Kotelnikov Gennadii P. , Kudashev Dmitrii S. , Lartsev Yurii V. , Zuev-Ratnikov Sergei D. , Dolgushkin Dmitrii A. , Asatryan Vardan G. , Shcherbatov Nikita D.
Published: February 2024

The review article presents the analysis of current organ-preserving surgical treatment methods for chondral defects of the knee joint from the standpoint of their pathogenesis. We systematized and provided comparative characteristics of the methods of joint-preserving surgical treatment of patients of this category with a critical analysis of various types of operations used for full-thickness and penetrating hyaline cartilage defects. Mosaic chondroplasty, one of the leading methods of surgical treatment for III- and IV-degrees defects (according to the ICRS classification), was considered in detail. The indications, contraindications and conditions for performing mosaic autoplasty of the articular surfaces of the knee joint were analyzed using the historical retrospective and the results of current research. We outlined several debatable provisions and problems of using the classical version of mosaic chondroplasty in case of destructive-dystrophic genesis of the osteochondral defect. The dogmatic approaches to chondroplasty were raised for discussion, as we consider them requiring critical revision.
The authors presented a detailed description of the developed new methods of mosaic chondroplasty relying on the current understanding of the pathogenesis of the knee osteoarthritis and osteonecrosis, as well as the role of the subchondral bone in the development of both these conditions and associated articular cartilage defects. The surgical instruments developed by the authors for the new methods of chondroplasty were described.
CLINICAL OUTCOMES OF SCLERAL BUCKLING COMBINED WITH PARS PLANA VITRECTOMY FOR RHEGMATOGENOUS RETINAL DETACHMENT
Authors: LUKANDY ANDRY , Sumanti Eugeni
Published: February 2024

Introduction and Objective: The various types of primary interventions for rhegmatogenous retinal detachment (RRD) include pars plana vitrectomy (PPV), scleral buckling (SB), and combination of both. Intraocular tamponade with silicone oil (SO) or expanding gas. This research was conducted to evaluate the clinical outcomes of SB combined with PPV as a treatment for RRD.
Methods: This research was prospective descriptive study with total sampling for RRD treated by SB combined with PPV from August 2022 to January 2023 in RSUP. Prof. Dr. R.D. Kandou. BCVA, IOP, clinical findings, intraocular tamponade and complications after the surgery were observed.
Results: Most of the patients was male with average age of 28 ± 40 years. RRD was observed in 6 eyes and laterality on right eye. BCVA was 2.5 ± 2 logMAR before the surgery and 2.3 ± 1 logMAR 1 month after the surgery. BCVA  day 1, 1 week, 2 weeks and 1 month showed no significant difference after the surgery compared to baseline (p = 0.317, p = 0.949, p = 0.611, p= 0.611 respectively). Preoperative IOP was 7 ± 11 mmHg and 13.6 ± 10 mmHg 1 month after the surgery. IOP 1 week and 1 month showed significant difference (p = 0.027, p=0.011). IOP day 1, 2 weeks and 1 month showed there was no significant difference after the surgery on day 1 and 2 weeks.
Conclusion: There were several clinical condition seen such as BCVA after the surgery didn’t improve as expected, subconjunctival bleeding was found the most as postoperative complications.
Keyword: Scleral buckling, Pars plana vitrectomy, silicon oil, retinal detachment
THE DIFFERENCE OF PREDICTED AND FINAL REFRACTION USING BU-II AND SRK/T FORMULA IN HIGH MYOPIA PATIENT AT DR. KARIADI HOSPITAL
Authors: Irlinda Riva , Fatimah Dyah Nur Astuti  , A. Kentar Arimadyo Sulakso  , Wisnu Sadasih  , A. Rizal Fanany
Published: February 2024

Introduction: Studies showed 38% refractive errors after intraocular lens (IOL) implantation are caused by deviations in calculation of IOL power. The difference between the formula’s refractive prediction and patient’s final outcome highly increases in cases of high myopia, but needs to be more research on this topic. This study aims to show difference between predicted and final refractive outcomes using Barrett II Universal (BU-II) and SRK/T in patients with high myopia who underwent phacoemulsification and IOL implantation.
Method: This analytical observational study with cross-sectional design was conducted on high myopia patients (axial length ? 26.0 mm) who underwent phacoemulsification and intraocular lens implantation between January 2021 and January 2022 at Dr. Kariadi General Hospital Semarang. Data used in this study consisted of biometric measurements and difference between predicted refractive outcomes using BU-II and SRK/T formulas and final refractive outcomes of patients one month after surgery. Data were analyzed using one-sample T-test, and significance level of p < 0.05 was considered statistically significant.
Results: Thirty-five eyes participated in this study, the mean axial length was (29.33  2.01). BU-II formula has mean difference in refraction prediction with patient's final refraction result closer to zero (1.191.31) than SRK/T formula (1.25  1,12). The difference between two formulas was statistically significant (p < 0.05).
Conclusion: The BU-II formula has lower difference between predicted and final refractive outcomes of high myopia patients after phacoemulsification and IOL implantation than SRK/T formula.
THE EXPRESSION OF ALPHA-SMOOTH MUSCLE ACTIN IN CONTRACTED SOCKET
Authors: Dwiamelia Theresia , Respatika Datu , Darajati Irene Titin , Dibyasakti Banu Aji , Utomo Purjanto Tepo , Supartoto Agus
Published: February 2024

Purpose: A contracted socket is considered a common complication in anophthalmic patients, with the resulting poor fitting of an ocular prosthesis. In severe cases where patients have had multiple previous reconstructive attempts, further socket contraction may result from fibrosis, leading to eventual surgical failure. Alpha-smooth muscle actin (?-SMA) is often used to identify pathologic fibroblasts. It may serve as a reliable marker for myofibroblast cells. The aim of the study was to find ?-SMA protein expression in myofibroblasts derived from orbital socket contracture.
Methods: In this study, we observed five patients with contracted sockets who underwent fornicoplasty and buccal graft surgery from October 2022 to February 2023. Tissue samples were taken from the conjunctival fornix area during the surgery and then examined for ?-SMA expression.
Result: In this study, there were 2 out of 5 (40%) positive ?-SMA expressions with history of recurrent contraction, 2 (40%) negative expressions with no history of recurrent contraction, and 1 result that could not be assessed due to the limited number of samples containing fibroblasts.
Conclusion: ?-SMA levels can be detected in patients with contracted sockets. Patients with a history of recurrently contracted sockets have a tendency to express positive ?-SMA. This may allow for the need for the administration of antimetabolites in patients with recurrent contracted sockets to avoid recurrence of this contracted socket.