bluuebunny/crossref_metadata_2025 huggingface dataset:
An Analysis of Sharia and Conventional Shares’ System at Indonesia Stock Exchange
Authors: Hersugondo Hersugondo , Sadiyah Cholimatul , Handriani Eka , Subagyo Herry , Astuti Sih Darmi
Published: August 2021

There are lots of alternative investing. It is started from investment real assets, securities, from conventional and manifold sharia. Islamic Capital market and conventional have some type securities which have different risk level of risks. A stock is one of securities among other securities that have the high level of risk. One of the risks that exists in the stock is fluctuations price, it is commonly called as volatility. The aim of this research is to identifiy the risk of sharia stock and conventional stock in Indonesia Stock Exchange (BEI) by using Jakarta Islamic Indekx (JII) and LQ45 Indeks variabels. In our research, we use time series started on 1 January 2015 to 10 October 2016 from yahoo finance with ARCH/GARCH and EGARCH models processed by Eview 8. Based on research finding with GARCH and EGARCH, this research tends to EGARCH. The fist finding shows that volatility stock JII lower, 0,075 than LQ45 0,0316. If volatility is higher, it means the stability degree lower. Both of those stocks are dominated by bad news and good news. Between JII and LQ45, the news respon is higher on LQ45. It means the volatility risk impact higher on LQ45. The third finding is the JII forecasting results through EGARCH has refrection proportion JII has smaller 0,194 than LQ45 0,678. It means that JII volatility is lower than LQ45.
Strategi Pengembangan LKMS-BMT Maslahah Sidogiri Pasuruan (Studi Analisis Pendekatan Interpretatif Struktural Modeling) (Strategy of LKMS-BMT Development Maslahah Sidogiri Pasuruan (Analysis Study of Structural Modeling Interpretative Approach))
Authors: Parmujianto Parmujianto
Published: August 2021

BMT (BMTM) is one of the LKMS that provides Sharia-based financial services. BMTM has not made specific identifications related to the behavior of the target audience which could potentially be a challenge in the future. This study uses a qualitative approach, namely descriptive analysis and Interpretative Structural Modeling (ISM). The results showed that consumer behavior in BMTM is positive in the utilization of BMTM products. Understanding and positive attitude towards BMTM products is based on the motives of daily necessities and business development. The efforts of BMT in building consumer loyalty to BMT by bringing services closer to the community, increasing the ratio of supervisors and discipline of supervision and developing several products according to community needs, as well as strengthening human resources.
Pengaruh Financial Technology Terhadap Perbankan Syariah: Pendekatan ANP-BOCR (The Influence of Financial Technology on Islamic Banking: ANP-BOCR Approach)
Authors: Muhammad Helmi , Sari Niki Puspita
Published: August 2021

The objective of this study was to examine the influence of financial technology (FinTech) on Islamic banking from the aspects of benefit, opportunity, cost and risk (BOCR). The research data were obtained through in-depth interviews and questionnaires from respondents which consisted of experts from academia, FinTech practicioners, Islamic banking practitioners and financial services authorities who were chosen by purposive sampling. The data analysis method of this research was Analytical Network Process (ANP) with the BOCR network structure approach. The results show that based on the priority aspects of the respondents' answers, rapid development of the FinTech industry provides positive opportunities for Islamic banking to implement strategic cooperation with the FinTech industry as a customer-oriented integral part.
The Role of Sharia Banks as Nazhir Partners in the Management of CWLS Retail SWR001 Investment Products
Authors: Dian Lailatullailia  , Setiyowati Arin , Wahab Abdul
Published: August 2021

Islamic social finance, one of which waqf should have a position and role that can synergize to contribute economically, considering Indonesia has the largest Muslim population in the world. The issue that the potential waqf assets of 2000 trillion with about 51,155.57 ha of waqf land that exists today has not been a productive asset that serves as a source of income in developing the people's economy. While the potential of cash waqf that reaches Rp 180 trillion (BWI) but collected around 391 billion. Therefore, needs the innovation of social finance-based investment scheme with the support of professionalization in its management (in this case nadzir board), one of which is LKS-PWU, especially Sharia Banking. Through State Sukuk instruments in the form of CWLS retail SWR001 products, the government and BWI involve Sharia Banking as Nazhir partners and distribution partners. This study aims to explain the role of sharia banking as nazhir partners in the management of Cash Waqf Linked Sukuk (CWLS) retail SWR001 investment products in the perspective of the basic principles of waqf. This research was conducted by qualitative research method, Library Research approach. Validity of data with source triangulation. The data analysis technique in this study is to use discourse analysis. The results showed that Policy, management and technical processes conducted by Sharia Banking in the management of CWLS Retail SWR001 both in terms of nazhir criteria, the process of collecting and distributing waqf funds is compatibility with the provisions of the Basic Principles of Waqf (PPW) at points 13, 15 and 17 in order to realize good governance for nazhir(Good Nazhir Governance). Keywords: Islamic Bank, Cash Waqf, CWLS Retail SWR001, Waqf Core Priciples (WCP), Good Nazhir Governance
Pre-Jurassic Formation Lithological Composition and Reservoir Characteristic Variation Analysis. Core and Field Tests Analysis in Frolovsky and Shaimsky Petroliferous Regions
Authors: Zadorozhnyaya Irina
Published: August 2021

Analysis of the lithology of rocks of the pre-Jurassic complex and changes in the reservoir properties of rocks is one of the most important and difficult tasks for the formation of a petrophysical model for the interpretation of well logging data. Despite the long history of geological and geophysical study of deposits of the pre-Jurassic complex, a number of issues related to the reflection in the geophysical parameters of rocks and characteristics of reservoir properties have been studied insufficiently. This is due to the high variability of the lithological composition, textural and structural heterogeneity of the volcanic-sedimentary strata of the Turin Group.

At present, the sediments of the pre-Jurassic complex are being actively studied - a representative core is purposefully selected, which is studied using an SCAL, including special methods, modern precision electrical, radioactive and acoustic studies are included in the complex of geophysical studies. The results of new studies are a good information base for refining the petrophysical model of an extraordinary object of study.

The aim of this work was to analyze the lithology and reservoir properties of rocks, as well as to identify and classify the main groups of rocks that are possible reservoirs in the sediments of the pre-Jurassic complex within the Frolovsky and Shaimsky petroliferous regions.
Consideration of the Influence of Carbonate Cement on the Accuracy of Prediction of Well Start-Up Flow Rates in Deep Reservoirs of the West Siberian Oil and Gas Basin on the Example of Reservoir U1 Formation
Authors: Mikhaylov Sergey Petrovich , Shtyrlyaeva Anastasia Andreevna
Published: August 2021

Oil reservoirs are often affected by tectonic processes throughout their lifetime. Tectonic processes contribute to the impact on the formation of a number of mechanical and chemical factors. These factors change the composition and structure of the reservoir and this affects the reservoir properties of the reservoir. Deep-seated reservoirs experience a longer and more intense impact of tectonic processes. A more detailed study of the composition and properties of reservoirs for an accurate forecast of reservoir properties and their productivity potential is due to this.

Standard log interpretation methods have been developed based on shallow strata. These methods do not allow taking into account secondary changes in the reservoir and make the calculations of the starting flow rates of wells reliable.

J1 stratum West Wing on Nizhnevartovsky set is a prime example of this.
Diffraction of Partial Temporal Coherence Beam From Multi Slits
Authors: Koushki Ehsan , ALAVI ALi
Published: August 2021

We have generalized the notion of Franhoufer diffraction of temporal coherent light from a single slit to the case of arbitrary n -slits. A general numerical method has been developed for the simulation of the diffraction pattern of multi-slits which is also used to study the effects of coherence length on the diffraction pattern. The diffraction pattern is investigated for different values of recently introduced parameter “decoherence parameter”. It is shown that for multi-slits, the temporal decoherence effects appear for . The results of our study reproduce the previous studies for perfect temporal case, when coherence length tends to infinity.
MEQA-RPL: A Mobility Energy and Queue Aware Routing Protocol for Mobile Nodes in Internet of Things
Authors: cyriac robin , MA Saleem Durai
Published: August 2021

Increase in mobile nodes has brought new challenges to IoT’s routing protocol-RPL. Mobile nodes (MN) bring new possibilities as well as challenges to the network. MN creates frequent route disruption, energy loss and increases end-to-end delay in the network. This could be solved by improving RPL to react faster to route failures through route prediction, while keeping energy expenditure for this process in reasonable limits. In this context a new Mobility Energy and Queue Aware-RPL (MEQA-RPL) is proposed that have the capability to sense route failure and to identify proactively the next possible route before the current route fails. While identifying the next route, MEQA-RPL employs constraint check on energy and queue availability to guarantee QoS for MN and better lifetime for the network. When compared to RPL with mobility support our model reduce average signaling cost by 31%, handover delay by 32% and improve packet delivery ratio by 17%. We run simulations with multiple mobile nodes which have also shown promising results on aforementioned parameters.
Functional Characterization of Lycopene Epsilon-Cyclase Genes in Nicotiana Tabacum
Authors: Song Weina , Wei Fang , Gao Shuwen , Dong Chen , Hao Jianfeng , Jin Lifeng , Li Feng , Wei Pan , Guo Jinggong , Wang Ran
Published: August 2021

Background:Lycopene epsilon-cyclase (ε-LCY) is a key enzyme in the carotenoid biosynthetic pathway (CBP) of higher plants. In previous work, we cloned two Ntε-LCY genes from allotetraploid tobacco (Nicotiana tabacum), Ntε-LCY2 and Ntε-LCY1, and demonstrated the overall effect of Ntε-LCY genes on carotenoid biosynthesis and stress resistance. However, their genetic and functional characteristics require further research in polyploid plants.Results: Here, we used CRISPR/Cas9 to obtain Ntε-LCY2 and Ntε-LCY1 mutants in allotetraploid N.tabacum K326. Ntε-LCY2 and Ntε-LCY1 had similar promoter cis-acting elements, including light-responsive elements. The Ntε-LCY genes were expressed in roots, stems, leaves, flowers, and young fruit, and their highest expression levels were found in leaves. Ntε-LCY2 and Ntε-LCY1 genes responded differently to normal light and high light stress. Both the Ntε-LCY2 and the Ntε-LCY1 mutants had a more rapid leaf growth rate, especially ntε-lcy2-1. The expression levels of CBP genes were increased in the ntε-lcy mutants, and their total carotenoid content was higher. Under both normal light and high light stress, the ntε-lcy mutants had higher photosynthetic capacities and heat dissipation levels than the wild type, and this was especially true of ntε-lcy2-1. The reactive oxygen species content was lower in leaves of the ntε-lcy mutants.Conclusion: In summary, the expression patterns and biological functions of the Ntε-LCY genes Ntε-LCY1 and Ntε-LCY2 differed in several respects. The mutation of Ntε-LCY2 was associated with a greater increase in the content of chlorophyll and various carotenoid components, and it enhanced the stress resistance of tobacco plants under high light.
It’s what you do, Not the way that you do it – Online Versus Face to Face Small Group Teaching in First Year Medicine.
Authors: Torda Adrienne , Shulruf Boaz
Published: August 2021

BackgroundMajor disruptions imposed on medical education by the COVID-19 pandemic and the rapid shift to online teaching in medical programs, necessitated need for evaluation of this format. In this study we directly compared knowledge outcomes, social outcomes, and wellbeing of first year student small group teaching in either face to face (f2f) or online format.MethodsAt the end of the first course of our medical program, students were invited to participate in an online questionnaire with 10 quantitative items and 1 qualitative item. These were analysed using Factor Analysis Pattern Matrix and linear regression to group items and assess relatedness. Qualitative responses were thematized using Qualtrics software (Qualtrics, Provo, UT, USA). Summative assessment results were compared, both between current cohorts to historical cohorts.ResultsFrom a cohort of 298 students there was a 77% response rate. Overall, there were no differences in knowledge gains, either between groups or when compared to historical cohorts. Questionnaire items fell reliably into groups that related to either learning outcomes, social outcomes, or wellbeing. Independent T tests showed that format for teaching (online versus f2f) had an impact on social outcomes but no direct impact on learning outcomes. Linear regression revealed that the social outcomes have a direct impact on wellbeing and almost the double the impact on learning outcomes than mode of learning ie. F2f or online (β=.448 and β=.232 respectively). ConclusionIn this study, we were able to show with statistical strength that social outcomes for students such as engaging with peers and facilitator, contributing to the group, and making friends have a direct impact on wellbeing and indirectly impact learning outcomes (such as motivation, satisfaction, integration of knowledge). In a rapidly changing educational landscape, it is vital that these aspects are a focus of design and delivery of medical education. The data from this study supports the notion that activity design and the expertise of the teacher in facilitating the small group activities, is more important than the mode of educational delivery itself.
Home Environment and Noise Annoyance in a National Sample of Multi-Family Buildings in Sweden- Associations with Stress-Related Symptoms
Authors: Wang Juan , Norbäck Dan
Published: August 2021

Background: Poor acoustic condition at home can have negative health impact. The aim was to investigate home environment factors and stress symptoms associated with noise annoyance. Methods: All adults (≥18 y) registered in selected apartments in Sweden were invited to participate in a questionnaire survey including medical questions and personal factors. Totally 5775 adults participated (response rate 46%). Information on home environment was obtained through an indoor environment questionnaire. Two-level logistic regression models (individual, municipality) were performed to estimate associations.Results: Totally 11.2% reported any frequent noise at home. Voice/radio/TV/music/similar sounds from neighbours (13.2%) and scraping sound/footsteps/thumping from neighbours (16.5%) and road traffic (16.1%). Younger participants reported more noise annoyance and more stress-related symptoms. Females were more sensitive to noise from neighbours and traffic noise causing severe effects. Noise annoyance was related to tiredness, headache and difficulty concentrating (OR=1.70-8.19), and noise annoyance from many sources was related to a higher risk of symptoms. A warmer climate (OR=1.30), buildings constructed from 1961-1985 (OR=1.50-1.85), renting (OR=1.83) and living alone (OR=1.42) were related to more noise annoyance. A warmer climate (OR=1.95), higher municipality population density (OR=1.24), a longer living time (OR=1.34), construction year (1961-1975) (OR=2.42), renting (OR=1.80-2.32), living above ground floor (OR=1.45) and having a bathroom fan (OR=1.84) were associated with increased noise annoyance from neighbours. Factors associated with increased noise annoyance from installations or ventilation/fans/heat pumps included a warmer climate, higher municipality population density, construction year (1961-1995), renting and any mechanical ventilation. Higher municipality population density, construction year (especially 1961-1985) and renting were associated with more noise annoyance from traffic (OR=1.77-3.92). Renting (OR=1.73) and living above ground floor (OR=1.60) were related to more severe traffic noise effects.Conclusions: The present study shows that noise annoyance may cause stress-related symptoms. Younger age, female gender, living alone, a longer living time, a warmer climate, higher municipality population density and building factors (renting, construction period 1961-1975, living above ground floor and mechanical ventilation system) were related to more noise annoyance.
ScLRTC: Imputation for Single-Cell RNA-Seq Data Via Low-Rank Tensor Completion
Authors: Li Zhong , Pan Xiutao , Qin Shengwei , Yu Minzhe , Hu Hang
Published: August 2021

Background: With single-cell RNA sequencing (scRNA-seq) methods, gene expression patterns at the single-cell resolution can be revealed. But as impacted by current technical defects, dropout events in scRNA-seq lead to missing data and noise in the gene-cell expression matrix and adversely affect downstream analyses. Accordingly, the true gene expression level should be recovered before the downstream analysis is carried out. Results: In this paper, a novel low-rank tensor completion-based method, termed as scLRTC, is proposed to impute the dropout entries of a given scRNA-seq expression. It initially exploits the similarity of single cells to build a third-order low-rank tensor and employs the tensor decomposition to denoise the data. Subsequently, it reconstructs the cell expression by adopting the low-rank tensor completion algorithm, which can restore the gene-to-gene and cell-to-cell correlations. ScLRTC is compared with other state-of-the-art methods on simulated datasets and real scRNA-seq datasets with different data sizes. Specific to simulated datasets, scLRTC outperforms other methods in imputing the dropouts closest to the original expression values, which is assessed by both the sum of squared error (SSE) and Pearson correlation coefficient (PCC). In terms of real datasets, scLRTC achieves the most accurate cell classification results in spite of the choice of different clustering methods (e.g., SC3 or t-SNE followed by K-means), which is evaluated by using adjusted rand index (ARI) and normalized mutual information (NMI). Lastly, scLRTC is demonstrated to be also effective in cell visualization and in inferring cell lineage trajectories.Conclusions: a novel low-rank tensor completion-based method scLRTC gave imputation results better than the state-of-the-art tools. Source code of scLRTC can be accessed at https://github.com/jianghuaijie/scLRTC.
Spill-overs and trade-offs for increasing livestock productivity
Authors: Acosta Alejandro , Cicowiez Martin
Published: August 2021

The overarching goal of the United Nations Food Systems Summit is to catalyze action for the transformations needed in food systems to accelerate the progress toward sustainable development goals (SDG). However, given the complexity of these interactions, gains in one area may determine losses in others. Using the Livestock Policy Simulation Model (LPSM), we assessed the effect of enhancing the productivity in the Ethiopian livestock sector by 2030. We show that an increase in productivity has several positive effects on GDP, employment generation, household consumption, and poverty reduction; however, these benefits might come at an environmental cost associated with a total increase in greenhouse gas emissions. Our results have important policy implications, showing that the achievement of some SDG targets could conflict with the accomplishment of others. The analysis illustrates the capacity of LPSM to integrate economic, social, and environmental dimensions while quantifying spillovers and trade-offs.
Research on Characteristic Recognition and Dangerous Prevention While Mining through Collapse Column of Pansan Minefield,China
Authors: Xu Haitao , yang hui , Sun Wenbin , Kong Lingjun , Zhang Peng
Published: August 2021

In order to find out the characteristics of geological isomer exposed in the mining process of 12318 working face in Pansan Mine and grasp its influence law on subsequent coal seams mining, the isomer was firstly determined as the collapse column by means of 3D seismic, transient electromagnetic detection, SYT detection and other methods, and its development characteristics, conductivity and water enrichment were identified.Then FLAC3D numerical simulation software was used to analyze the characteristics of vertical stress and plastic failure zone in different coal seams during mining.Finally, by comparing the ultimate failure depth of floor and the thickness of waterproof layer in the process of each coal seam directly pushing through the collapse column, the risk of water inrush and the prevention are analyzed.The results show that the exposed geological isomer is characterized by weak water-rich collapse column.Under the influence of the mining of the previous coal seam and the activation of the collapse column, the subsequent coal seam is in the low stress area before mining, which increases the floor failure and causes the activation of the collapse column more easily during mining.Coal 5# and 4# can be directly pushed through the collapse column, and coal pillar of sufficient width should be left for coal 1# to prevent the collapse column from activating water inrush.
Na+/H+-Exchanger Family As Novel Prognostic Biomarkers In Colorectal Cancer
Authors: Zhou Xin , Jiang Manman , Liu Zhihong , Xu Mengmeng , Chen Nannan , Wu Ziyu , Gu Changji , Chin Eugene , Yang Xiaodong
Published: August 2021

Background: The acidic characteristics of the tumor microenvironment (TME) are attributed to cancer cells’ needs of metabolism that produce a large amount of H+. In order not to affect its own life activities, it needs to release H+ into the intercellular space through an efficient Na+/H+ exchanger. On account of the intestine whose physiological function is highly dependent on intestinal pH value, NHE family members may play a critical role in the occurrence and development of colorectal cancer (CRC).Methods: TCGA, GEPIA2, ONCOMINE, UALCAN, STRING, TIMER, Cytoscape, TargetScan, ENCORI, LncBase v.2, DNMIVD, HPA and CellMinerTM databases were used in our study.Results: The mRNA expression of SLC9A1, SLC9A2, SLC9A3 and SLC9A9 were evidently lower in COAD compared to normal samples, however, mRNA expression of SLC9A5, SLC9A8 and SLC9B2 were higher. Besides, mRNA expression of NHE family were extremely associated with clinicopathological features, tumor immune microenvironment and stemness score, DNA methylation and patient prognosis in COAD. Moreover, we conjectured that NHE family may play a role through MAPK or ErbB signaling pathway according to the results of GO/KEGG enrichment analysis. At last, we found that NHE family members were key factors of various kinds of cancers.Conclusion: Our study indicated that NHE family was new diagnostic and therapeutic targets for CRC, which could have important significance for the clinical treatment of CRC.
Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severity
Authors: Zhang Wuji , Chua Brendon , Selva Kevin , Kedzierski Lukasz , Ashhurst Thomas , Haycroft Ebene , Shoffner Suzanne , Hensen Luca , Boyd David , James Fiona , Mouhtouris Effie , Kwong Jason , Chua Kyra , Drewett George , Copaescu Ana , Dobson Julie , Rowntree Louise , Habel Jennifer , Allen Lilith , Koay Hui-Fern , Neil Jessica , Gartner Matthew , Lee Christina , Andersson Patiyan , Seemann Torsten , Sherry Norelle , Amanat Fatima , Krammer Florian , Londrigan Sarah , Wakim Linda , King Nicholas , Godfrey Dale , Mackay Laura , Thomas Paul , Nicholson Suellen , Arnold Kelly , Chung Amy , Holmes Natasha , Smibert Olivia , Trubiano Jason , Gordon Claire , Nguyen Thi , Kedzierska Katherine
Published: August 2021

Although the respiratory tract is the primary site of SARS-CoV-2 infection and the ensuing immunopathology, respiratory immune responses are understudied and urgently needed to understand mechanisms underlying COVID-19 disease pathogenesis. We collected paired longitudinal blood and respiratory tract samples (endotracheal aspirate, sputum or pleural fluid) from hospitalized COVID-19 patients and non-COVID-19 controls. Cellular, humoral and cytokine responses were analysed and correlated with clinical data. SARS-CoV-2-specific IgM, IgG and IgA antibodies were detected using ELISA and multiplex assay in both the respiratory tract and blood of COVID-19 patients, although a higher receptor binding domain (RBD)-specific IgM and IgG seroconversion level was found in respiratory specimens. SARS-CoV-2 neutralization activity in respiratory samples was detected only when high levels of RBD-specific antibodies were present. Strikingly, cytokine/chemokine levels and profiles greatly differed between respiratory samples and plasma, indicating that inflammation needs to be assessed in respiratory specimens for the accurate assessment of SARS-CoV-2 immunopathology. Diverse immune cell subsets were detected in respiratory samples, albeit dominated by neutrophils. Importantly, we also showed that dexamethasone and/or remdesivir treatment did not affect humoral responses in blood of COVID-19 patients. Overall, our study unveils stark differences in innate and adaptive immune responses between respiratory samples and blood and provides important insights into effect of drug therapy on immune responses in COVID-19 patients.
Perception of Undergraduates and Postgraduates pertaining online Learning during the COVID-19 Pandemic: a Cross-sectional Study amongst Sudanese Health Professional Students
Authors: Fadl Hiba Awadelkareem Osman , Hamza Abdelrahman Hamza  Abdelmoneim , Eissa Mahir Eissa  Mohamed , Osman Hadeel Idris Adam , Ali Hiba Ali Ibrahim , Mohamed Noha Abdalla Yousif
Published: August 2021

Background: The novel coronavirus (COVID-19) pandemic has impacted all aspects of life including educational services due to partial and complete lockdown. In Sudan, education is based on the traditional method of learning (face-to-face lectures) in a classroom. However, the sudden outbreak of COVID-19 made some educational institutes especially Universities and colleges resort to online learning. This study aimed to assess the Perception of Health professional students included under and postgraduates concerning the possible application of online learning during the COVID-19 pandemic in Sudan 2020.Methods: A Cross-Sectional study was conducted amongst Sudanese Health professional Students, included Undergraduates and postgraduates. A convenient sample collection method was used via a self-administrated online structured questionnaire of nineteen questions, which were validated by a medical education expert. The perception was assessed and data were analyzed using a statistical package for social science (SPSS).Results: A total of 133 Health Professional students responded to the web questionnaire.97 (73%) were undergraduates and 36(27%) were postgraduates. Among undergraduates, 58(59.8%) were expressing positive perception, while 39(40.2%) had a negative perception. Whereas 24 (66.7%) of Postgraduates had positive perceptions and 12(33.3%) of them expressed a negative perception about online learning.Conclusions: Postgraduate health professionals are more familiar and stating a higher level of perception compared to the undergraduates, furthermore, several students already were exposed to hybrid online learning during the current COVID-19 Pandemic. Several obstacles to the implementation of online learning in Sudan were noticed by the participating students in this study, which must be appropriately managed for the successful implantation of this mode of learning.
How (Dis)trust in Scientific Information Links Political Ideology and Reactions Toward the Coronavirus Pandemic: Associations in the U.S. and Globally
Authors: McLamore Quinnehtukqut , Syropoulos Stylianos , Leidner Bernhard , Hirschberger Gilad , Young Kevin , Zein Rizqy , Baumert Anna , Bilewicz Michal , Bilgen Arda , Bezouw Maarten van , Chatard Armand , Chekroun Peggy , Chinchilla Juana , Choi Hoon-Seok , Euh Hyun , Gomez Angel , Kardos Peter , Khoo Ying Hooi , Li Mengyao , Légal Jean-Baptiste , Loughnan Steve , Mari Silvia , Tan-Mansukhani Roseann , Muldoon Orla , Noor Masi , Paladino Maria Paola , Petrović Nebojša , Selvanathan Hema Preya , Uluğ Özden , Wohl Michael , Yeung Wai Lan Victoria
Published: August 2021

U.S.-based research suggests conservatism is linked with less concern about contracting coronavirus and less preventative behaviors to avoid infection. Here, we investigate whether these tendencies are partly attributable to distrust in scientific information, and evaluate whether they generalize outside the U.S., using public data and recruited representative samples across four studies (Ntotal=37,790). In Studies 1–3, we examine these relationships in the U.S., yielding converging evidence for a sequential indirect effect of conservatism on compliance through scientific (dis)trust and infection concern. In Study 4, we compare these relationships across 19 distinct countries, finding that they are strongest in North America, extend to support for lockdown restrictions, and that the indirect effects do not fully appear in any other country in our sample other than Indonesia. These effects suggest that rather than a general distrust in science, whether or not conservatism predicts coronavirus outcomes depends upon national contexts.
Assimilation of Zinc Metal Ion With Hydroxyapatite for Impedance Studies
Authors: K POOVENDRAN , Wilson K.S. Joseph
Published: August 2021

The aim of the present work is to examine the doping outcome of Zn metal ions on hydroxyapatite for different concentrations (0.2, 0.4, 0.6, and 0.8). The samples for the pure and Zn doped HAp are synthesized by wet chemical precipitation method. The properties and the particle size are identified by using XRD. The functional bands of PO, CO and OH are analyzed through FTIR and the surface morphology and particle shapes are studied through SEM. The elemental analysis such as zinc, calcium and phosphates are analyzed by EDAX. All the designed elements are studied and confirm the (Ca+Zn)/PO ratio is nearly 1.67 and no other elements were identified in this study. The morphological particles of needle shape and the nanoscale particle size and shapes are studied by using TEM. The electrical conductivity of the synthesized ZnHAp ceramic is mainly related to width of the channel and the polarizability. The frequency dependence of the electric and dielectric properties was studied by using impedance spectroscopy.
CNS Imaging Characteristics in Fibromyalgia Patients With and Without Peripheral Nerve Involvement
Authors: Aster Hans-Christoph , Evdokimov Dimitar , Braun Alexandra , Üçeyler Nurcan , Kampf Thomas , Pham Mirko , Homola György , Sommer Claudia
Published: August 2021

We tested the hypothesis that reduced skin innervation in fibromyalgia syndrome is associated with specific CNS changes. This prospective case-control study included 43 women diagnosed with fibromyalgia syndrome and 40 healthy controls. We further compared the fibromyalgia subgroups with reduced (n=21) and normal (n=22) skin innervation. Brains were analysed for cortical thickness, for white matter integrity, and for functional connectivity. Compared to controls, cortical thickness was decreased in the left pars opercularis in the fibromyalgia group as a whole, and decreased in the left superior frontal and left rostral middle frontal cortex in the fibromyalgia subgroup with reduced skin innervation. Diffusion tensor imaging revealed a significant increase in fractional anisotropy in the corona radiata, the corpus callosum, cingulum and fornix in patients with fibromyalgia compared to healthy controls. Using resting-state fMRI, the fibromyalgia group as a whole showed functional hypoconnectivity between the right midfrontal gyrus and the posterior cerebellum and the right crus cerebellum, respectively. The subgroup with reduced skin innervation showed hyperconnectivity between the right cuneal cortex and the anterior parahippocampal gyrus, between the left thalamus and the lateral parietal region in the default mode network and hypoconnectivity between the left frontal lobe and the right cerebellum crus 1. Our results suggest that the subgroup of fibromyalgia patients with pronounced pathology in the peripheral nervous system shows distinctly altered morphology, structural and functional connectivity also at the level of the brain. We propose considering these subgroups when conducting clinical trials.
Missed Nursing Care in COVID-19 Patients in Iran
Authors: Hosseini Zeinab , Reisi Leila , Maghari Amir Hossein , Karimollahi Mansoureh
Published: August 2021

ObjectivesNursing care is one of the most important tasks of nursing. Providing safe and high-quality nursing care will improve the patient as soon as possible and reduces the complications of the disease. Due to the corona epidemic in the last year, nurses cannot provide all the necessary care for patients; a series of care is eliminated or delayed or reduced, which is called missed nursing care. So, this study aimed to investigate the missed nursing care and the reasons affecting it in the corona wards in Ardabil.Study designThe research is conducted in a cross-sectional manner. The research included 135 nurses who worked in Ardabil's corona wards.Data collection/extraction methodsThe Missed Nursing Care Questionnaire, was used to collect data. The significance level of statistical tests set at 0.05.Principal findingsMost of whom were women, 135 nurses participated in the study and had a bachelor's degree in nursing. Supportive and necessary care is missed more than other care; According to nurses, the most common reasons for the missed care were emergencies, low staffing, and an increase in the number of patients.ConclusionsAs a result of the findings, being in a fresh and uncertain situation, as well as an increase in the number of patients, has resulted in a loss of nursing care. By controlling these factors, the missed care in the ward can be controlled, and increase the satisfaction of patients and nurses.
Realignment of Ideal Lumbar Lordosis in Correction Surgery: A Novel Predictive Formula
Authors: Chen Kai , Yang Yilin , Wang Heng , Zhou Tianjunke , Zhai Xiao , Yang Changwei , Li Ming
Published: August 2021

Study design: Retrospective cohort studySummary of Background Data：Restoring the sagittal balance is the significant procedure, which could be evaluated by the relationship of thoracic kyphosis (TK) and lumbar lordosis (LL). Several lumbar lordosis predictive formulas have been proposed. But previous study ignored importance of reciprocal relationship between regional spinal modifications in some ways.Objectives: Realignment of the lumbar lordosis is fundamental in spinal surgery and several formulas have been established to predict the appropriate lumbar lordosis. However, the predictive accuracy of these formulas did not reach their targets. The present study introduced a novel predictive formula for realignment of lumbar lordosis in correction surgery, aiming to predict the individualized ideal lumbar lordosis for different patients.Methods: A total of 311 asymptomatic volunteers were recruited: 220 volunteers for the development of the formula, and the other 91 subjects for validation. General and radiological parameters were evaluated. Correlation analysis between maxLL and other parameters was performed. Multiple regression analysis was conducted to establish the predictive formula using variables related to maxLL. Comparison between predicated maxLL yielded by our formula and other 7 formulas and actual maxLL were conducted to determine the reliability and validity of our predictive formula.Results: MaxLL was correlated with maxTK, SS, PT and PI (all P<0.05). The adjusted multiple regression analysis showed that there were significant associations of maxLL with maxTK and PI (all P<0.001), and the formula was established as follows: maxLL=0.6*maxTK+0.5*PI+3. No significant difference was found between actual maxLL and predicted maxLL yielded by our formula (P=0.408), and our predictive formula has been demonstrated sound reliability and validity. Conclusion: MaxTK and PI were the primary contributors to maxLL, and our novel formula could be safely utilized to predict the ideal lumbar lordosis for patients before surgery.
IL-33 Induces ADAMTS5 Expression and Cell Migration in Glioblastoma Multiforme
Authors: Yildiz Dilara Akcora , Yukselten Yunus , Sunguroglu Merve , Ugur Hasan Caglar , SUNGUROGLU Asuman
Published: August 2021

Glioblastoma multiforme (GBM), characterized by a high rate of proliferation and migration capacity, is an incurable brain tumor in adults. Interleukin-33 (IL-33), a member of the IL-1 cytokine superfamily and a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5), a family of zinc dependent metalloproteinases are known to have an essential roles in GBM migration and invasion. Previous studies have separately revealed elevated expressions of IL-33 and ADAMTS5 in GBM; however, the interaction between IL-33 and ADAMTS5 in GBM pathogenesis has remained unclear. Here, using publically available GlioVis and GEPIA programs, we showed that mRNA expression of IL-33 and ADAMTS5 is significantly high in GBM cells, and a positive correlation between IL-33 and ADAMTS5 was also determined in these cells. In parallel with the mRNA data of IL-33 and ADAMTS5, by Western blot analysis, protein levels were found to be elevated in GBM tissues and increased gradually with the disease progression. Primary GBM cells and low-grade glioma cells were then treated with IL-33 to examine its stimulating effect on ADAMTS5 expression. Exposure to IL-33 raised ADAMTS5 protein levels in a dose-dependent manner. Finally, the wound healing method was performed to confirm the impact of IL-33 on migration in primary GBM cells. IL-33 promoted migration of primary GBM cells three-times higher than untreated GBM cells. Thus, the current study suggests for the first time that IL-33 might have a role in play a part in GBM progression through induction of ADAMTS5 expression and promotion of migration in GBM cells.
Comprehensive Evaluation of Transition Metal Doped Ni3N to Construct High-Efficiency Hydrogen Evolution Catalyst
Authors: Wang Meng , Lv Zepeng , Lv Xuewei , Li Qian , Dang Jie
Published: August 2021

Density functional theory (DFT) calculation indicators (ΔG, densities of state, D-band and bader charge) are commonly used to predict and analyze the hydrogen evolution reaction (HER) activity of catalysts, and most studies discuss only one or few of these indicators’ impact on catalysis, but still no report has comprehensively evaluated the influence of all these indicators on catalytic performance. Herein, foreseen by comprehensive consideration first, we report transition metal doped Ni3N nanosheets combined on Ni foam for utra-efficient alkaline hydrogen evolution. For dual transition metals doped Ni3N, Co,V-Ni3N exhibits remarkable HER performance with a significantly low overpotential of only 10 mV in alkaline electrolyte and 41 mV in alkaline seawater electrolyte at 10 mA cm− 2; while for single transition metal doped Ni3N, V-Ni3N exhibits the best performance with an overpotential of 15 mV and a Tafel slope of 37 mV dec− 1. Our work highlights the importance of comprehensive evaluation of DFT calculation indexes, and opens up a new method for the rational design of efficient and low-cost catalysts.
Mortality Rate of People Exposed To Mustard Gas During Iran-Iraq War in Sardasht, Iran: A 32 Years Retrospective Cohort Study
Authors: Rabiee Mohammad Hasan , Ghanei Mostafa , Amini Hossein , Akhlaghi Aliasghar
Published: August 2021

Background:Mustard gas is one of the most widely used chemical weapons in the past century. However little information exists concerning long-term mortality due to mustard gas exposure. In this study we investigated mortality rate among civilian people exposed to mustard gas during Iran-Iraq war in sardasht in Iran after 32 years.Methods:In this retrospective cohort study, data related to all people exposed to mustard gas in sardasht in 1987 were extracted from the Veterans and Martyr Affair Foundation of Iran up to March 20, 2019. Mortality rate, cumulative mortality and standardized mortality ratio with 95 % confidence interval were calculated to explain mortality in the cohort and compare it with Iranian general population. Cox regression analysis used to indicate factor affected risk of death in the cohort. Results:Out of 1,203 exposed people at the beginning of the period, 148 people died by the end of the study, with an average age of 66.42 at the time of death. Total person-years of the people up to end of the study were 38198.63 and mortality rate was equal to 387 per 100,000 persons-years. Total number of observed deaths was less than expected death and the all-cause standardized mortality ratio (SMR) was 0.680. Cause-specific SMR showed that observed death due to respiratory diseases was higher than expected (SMR: 1.75). The results of univariate and multivariate cox regression analysis showed that increasing age and having severe late complication in lung increase risk of death among people in the cohort. Conclusion:In general, this result indicated that acute exposure to mustard gas, even without wearing protective clothing and masks, will not increase all-cause mortality after 32 years if accompanied by special and ongoing care for those exposed.
Molecular Characterization and Pathogenesis of the Baculovirus Anprnpv Causing Tiger Band Disease in Antheraea Proylei (Oak Tasar Silkworm)
Authors: Khajje Diksha , Devi Sinam Subharani , Jagadish Anupama , Dubey Himanshu , Sivaprasad Vankadara , Terenius Olle , Muthusamy Ponnuvel Kangayam
Published: August 2021

The temperate oak tasar silkworm Antheraea proylei is frequently infested by tiger band disease caused by Antheraea proylei nucleopolyhedro virus (AnprNPV). The disease is characterised by dark tiger-like strips across the body of the silkworm, causing an increased mortality and poor seed cocoon recovery. The study confirms that the spread of the disease is particularly high in autumn seasons pertaining to high temperature and humidity conditions. The virus displays a higher copy number in the fatbody tissue and is also able to spread and multiply in various development stages such as egg, larvae, pupa and moth of infected A. proylei silkworms. To check the cross-infectivity of the virus on the silkworm species Antheraea pernyi, A. frithi and Samiaricini and some other lepidopteran species (Phalera raya, Hablaea peura, Pieris canidiaand P. brassicae), virus inoculum was introduced into early-stage larvae. All the silkworm species died acquiring the infection, whereas inoculation into other lepidopteran pests did not have any impact on their survival, indicating the host range of this virus was limited to the silkworm clade. The virus follows a transovum vertical transmission route where hatched larvae laid by infected mother moths were found to contain virus. The surface of eggs is identified to be the potential source of infection since poorly washed eggs displayed the presence of virus on the outer surface whereas was absent in the inner contents of the surface-washed eggs. Hence, a surface disinfection method with 0.2% sodium hypochlorite has been devised from this study that can prevent the occurrence and spread of this virus. Similarly, a PCR as well as an qRT-PCR method has been developed for detection of the virus during early stages of infection in A. proylei silkworms.
Hypertension associated with unhealthy lifestyle and marked by serum cortisol levels
Authors: Hu Chunsong , Wu Yanqing , Li Juxiang , Wang Menghong , Ge Yuzhi , Tkebuchava Tengiz , Wu Qinghua
Published: August 2021

There are more and more individuals with hypertension due to major risk factors (mRFs) related to unhealthy lifestyle. Here, we report that a new type of hypertension associates with unhealthy lifestyle and marks by serum cortisol levels, which is termed C-type hypertension (CtH). All subjects collected at random at outpatient department between 2012 and 2017, with or without family history of hypertension, with or without unhealthy “environment-sleep-emotion-exercise-diet” intervention [E(e)SEEDi] related mRFs, were screened and measured serum cortisol levels (8:00 AM and 4:00 PM) and blood pressure. Typical cases with CtH have unhealthy E(e)SEEDi related mRFs, such as stay up later or OSA (+++), psychological pressure or bad emotion, lack of physical exercise or sitting for a long time, heavy smoking and/or liquor drinking. Day serum cortisol levels (8:00 AM and 4:00 PM) in this group were significantly elevated (vs control group, P<0.01). Follow-up analysis showed that the outcomes were closely linked to these individuals’ lifestyle and adherence to treatment. In conclusion, this study suggested that there is indeed CtH. Most are young and middle-aged individuals and easy to suffer from major adverse cardiovascular events (MACEs).
Peripheral Lymphocyte Count, Free/Total PSA Ratio, LUTS Predict The Severity of Prostatic Inflammation in BPH Patients
Authors: Wan Shun , Sun Xiao-Hong , Lin Yong-Shuai , Du Fang-Ming , Guo Gong-Jun , Yang Zhi , Mi Jun , Fu Yu-Qiang
Published: August 2021

Objective To study the correlation between peripheral blood lymphocytes, f/t PSA and LUTS symptoms, and prostatic inflammation in BPH patients.Materials and Methods From May 2020 to October 2020, 120 patients (aged 56-85 years) with BPH undergoing elective transurethral resection of the prostate (TURP) were selected. Peripheral blood lymphocyte counts and f/t PSA values were measured preoperatively, and IPSS scores were assessed. Postoperative prostate tissues were sent for pathological examination, and the relationship between peripheral blood lymphocyte count, TPSA, f/t PSA values, relevant clinical laboratory parameters, and relevant LUTS symptoms and the distribution of prostate tissue inflammation was analyzed.Results with the aggravation of prostatic inflammation, IPSS score and TPSA value were lower, while f/t PSA value and lymphocyte count were lower. Multivariate logistic regression analysis of 120 BPH patients showed that age (> = 60) [odds ratio (OR) = 0.29, 95% CI = 0.31-2.10; P = 0.02], IPSS score [OR = 1.24, 95% CI = 1.13-1.37; P < 0.01], TPSA [OR = 1.10, 95% CI = 1.02-1.19; P = 0.02], f/t PSA [OR = 1.03, 95% CI = 0.01-0.15; P = 0.02], and lymphocytes [OR = 1.70, 95% CI = 0.78-3.77; P = 0.04] were related to the formation of prostatic inflammation in BPH patients. Conclusion Peripheral blood lymphocyte count, TPSA, LUTS severity, and f/t PSA ratio can predict the severity of prostatic inflammation, which may be used as diagnostic markers for BPH patients with LUTS symptoms who have prostatitis and promote the development of drug treatment for LUTS symptoms in BPH patients with prostatitis.