bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Nilai-Nilai Huma Betang Dalam Menciptakan Sekolah Ekoliterasi
Authors: Sihotang Sesilia Stefania , Karliani Eli
Published: June 2024

Nilai Huma Betang adalah warisan budaya Dayak yang mengedepankan kebersamaan, kearifan lokal, dan keberlanjutan lingkungan. Penelitian ini bertujuan untuk menganalisis implementasi nilai Huma Betang dalam menciptakan sekolah ekoliterasi di SD Negeri 2 Petuk Ketimpun pada siswa kelas awal. Metode penelitian yang digunakan adalah studi kasus dengan pendekatan kualitatif. Data dikumpulkan melalui observasi, wawancara, dan studi dokumentasi. Informan adalah guru, dan kepala sekolah serta siswa pada kelas awal. Hasil penelitian menunjukkan bahwa implementasi nilai Huma Betang telah memberikan kontribusi signifikan dalam menciptakan sekolah ekoliterasi di SD Negeri 2 Petuk Ketimpun. Hal ini terlihat dari upaya sekolah dalam memadukan kurikulum formal dengan pendekatan lokal yang berbasis kearifan lokal, seperti pembelajaran di alam terbuka, penggunaan sumber daya lokal sebagai media pembelajaran, dan pengenalan budaya lokal kepada siswa. Selain itu, nilai-nilai seperti gotong royong, kebersamaan, dan rasa tanggung jawab terhadap lingkungan juga ditanamkan melalui berbagai kegiatan ekstrakurikuler dan program sosial di sekolah. Dengan demikian, implementasi nilai Huma Betang tidak hanya memperkaya pengalaman belajar siswa tetapi juga membantu dalam membentuk sikap dan perilaku ekoliterasi yang berkelanjutan. Penelitian ini memberikan kontribusi penting dalam memperkuat hubungan antara pendidikan formal dan kearifan lokal serta menunjukkan relevansi nilai-nilai budaya dalam konteks pendidikan ekoliterasi. Implikasi praktis dari penelitian ini adalah pentingnya integrasi nilai-nilai budaya lokal dalam pengembangan kurikulum sekolah untuk menciptakan generasi yang peduli dan bertanggung jawab terhadap lingkungan.
The current economics and throughput of single cell proteomics by liquid chromatography mass spectrometry
Authors: Smythers Amanda , Orsburn Benjamin
Published: June 2024

Single cell proteomics by mass spectrometry (SCP) is an emerging field of study that has captured the interest and imagination of biologists in a wide array of disciplines. In the pursuit of this new field a dizzying array of technologies and techniques have demonstrated the ability to quantify hundreds to a few thousand proteins in single mammalian cells of typical size. One striking characteristic of these methods is the wide range of relative costs associated with the analysis of each single cell. We have attempted to estimate the cost per cell across 17 different studies based on quotes we have obtained for hardware, reagents and instrument support plans in relation to number of cells that can be analyzed per day. Before including labor or facilities, we find that the cost to analyze a single mammalian cell of typical size can range from less than <$2 per cell to over $50 per cell. The increase in cost appears directly related to the decrease in relative throughput as measured in theoretical maximum number of cells analyzed per day. Perhaps the most surprising observation is that the average number of single cells analyzed across these studies appears to decrease each year. This is striking when compared to the emergence of single cell RNA sequencing where throughput increased, and cost/cell decreased exponentially over the first 7 years of the field’s emergence. While we have made many assumptions to obtain these estimates, we hope that these will be informative for scientists interested in obtaining SCP data and for mass spectrometrists who are considering entering this new field. We have provided a spreadsheet with a simple calculator in the supplemental data to allow others to adjust our calculations based on other variables and new methods which will inevitably be described in the future.
Non-Markovian Dynamic Models Identify Non-Canonical KRAS-VHL Encounter Complex Conformations for Novel PROTAC Design
Authors: Qiu Yunrui , Wiewiora Rafal P. , Izaguirre Jesus A. , Xu Huafeng , Sherman Woody , Tang Weiping , Huang Xuhui
Published: June 2024

Targeted protein degradation (TPD) is emerging as a promising therapeutic approach for cancer and other diseases, with an increasing number of programs demonstrating its efficacy in human clinical trials. One notable method for TPD is Proteolysis Targeting Chimeras (PROTACs, or heterobifunctional degraders) that selectively degrade a protein of interest (POI) through E3-ligase induced ubiquitination followed by proteasomal degradation. PROTACs utilize a warhead-linker-ligand architecture to bring the POI (bound to the warhead) and the E3 ligase (bound to the ligand) into close proximity. The resulting non-native protein-protein interactions (PPIs) formed between the POI and E3 ligase lead to the formation of a stable POI-degrader-ligase ternary complex, enhancing cooperativity for TPD. A significant challenge in PROTAC design is the time-consuming and resource-intensive screening of the degrader linkers to induce favorable non-native PPIs between POI and E3 ligase. In this work, we present a physics-based computational protocol to systematically predict non-canonical and metastable PPI interfaces between an E3 ligase and a given POI, aiding in the design of linkers to stabilize the PROTAC ternary complex and enhance degradation. In our protocol, we build the non-Markovian dynamic model using the Integrative Generalized Master Equation (IGME) method from approximately 1.5 millisecond all-atom molecular dynamics (MD) simulations of linker-less encounter complex, to systematically explore the inherent PPIs between the oncogene homologue (KRAS) protein and the von Hippel-Lindau (VHL) E3 ligase. Our IGME model successfully revealed six metastable states each containing a different PPI interface. We selected three of these metastable states containing promising PPIs for linker design. Our selection criterion included the thermodynamic and kinetic stabilities of these PPIs and the accessibility of the linker to the solvent-exposed sites on the warheads and the E3 ligand. One of our selected PPIs closely matches a recent co-crystal PPI interface structure induced by an experimentally designed PROTAC with potent degradation efficacy. We anticipate that our IGME approach has significant potential for widespread application in predicting metastable POI-ligase encounter complex interfaces that can enable subsequent rational design of novel PROTACs.
Au(I)-catalysis Enables Regioselective Hydrogen Isotope Labeling of Indoles
Authors: Milcendeau Pierre , Colonna Pierre , Ramdani Mohammed , Garcia Argote Sebastien , Glinsky-Olivier Nicolas , Pieters Grégory , GUINCHARD Xavier
Published: June 2024

The gold(I)-catalyzed hydrogen isotope exchange reaction on indoles and related heterocycles is described, under mild conditions and low catalyst loadings, using CD3OD and D2O as readily available deuterium sources. C3-unsubstituted indoles are labeled at the C3 position with an exquisite regioselectivity, while C3-substituted indoles are labeled at the C2 position. The reaction tolerates a number of chemical functions including amines, alcohols, aldehydes, in addition to the most classical functional groups. This method has been applied to the deuterium label-ing of densely functionalized bioactive compounds and to the synthesis of a tritiated analogue of pindolol using tritiated water as isotopic source. Mechanistic study revealed the involvement of aurated indole as key intermediates.
Chromophore Optimization in Organometallic Au(III) Cys Arylation of Peptides and Proteins for 266 nm Photoactivation
Authors: Silzel Jacob , Chen Chengwei , Sanchez-Marsetti Colomba , Farias Phillip , Carta Veronica , Harman W. Hill , Julian Ryan
Published: June 2024

Cysteine is the most reactive naturally occurring amino acid due to the presence of a free thiol, presenting a tantalizing handle for covalent modification of peptides/proteins. Although many mass spectrometry experiments could benefit from site-specific modification of Cys, the utility of direct arylation has not been thoroughly explored. Recently, Spokoyny and coworkers reported a Au(III) organometallic reagent that robustly arylates Cys and tolerates a wide variety of solvents and conditions. Given the chromophoric nature of aryl groups and the known susceptibility of carbon-sulfur bonds to photodissociation, we set out to identify an aryl group that could efficiently cleave Cys carbon-sulfur bonds at 266 nm. A streamlined workflow was developed to facilitate rapid examination of a large number of aryls with minimal sample using a simple test peptide, RAAACGVLK. We were able to identify several aryl groups that yield abundant homolytic photodissociation of the adjacent Cys carbon-sulfur bonds with short activation times (<10 ms). In addition, we characterized the radical products created by photodissociation by subjecting the product ions to further collisional activation. Finally, we tested Cys arylation with human hemoglobin, identified reaction conditions that facilitate efficient modification of intact proteins, and evaluated the photochemistry and activation of these large radical ions.
Embedded Many-Body Green's Function Methods for Electronic Excitations in Complex Molecular Systems
Authors: Tirimbo Gianluca , Sundaram Vivek , Baumeier Björn
Published: June 2024

Many-body Green's function theory in the GW approximation with the Bethe--Salpeter equation (BSE) provides a powerful framework for the first-principles calculations of single-particle and electron-hole excitations in perfect crystals and molecules alike. Application to complex molecular systems, e.g., solvated dyes, molecular aggregates, thin films, interfaces, or macromolecules, is particularly challenging as they contain a prohibitively large number of atoms. Exploiting the often localized nature of excitation in such disordered systems, several methods have recently been developed in which GW-BSE is applied to a smaller, tractable region of interest that is embedded into an environment described with a lower-level method. Here, we review the various strategies proposed for such embedded many-body Green's functions approaches, including quantum-quantum and quantum-classical embeddings, and focus in particular on how they include environment screening effects either intrinsically in the screened Coulomb interaction in the GW and BSE steps or via extrinsic electrostatic couplings.
Ion- Exchange of Zeolitic Brønsted Acid Sites with Metal Cations Influences the Hydrocarbon Pools (HCP) during Tandem CO2 Hydrogenation
Authors: Mahnaz Fatima , Dharmalingam Balaji C. , Mangalindan Jasan Robey , Vito Jenna , Varghese Jithin John , Shetty Manish
Published: June 2024

We demonstrate that the exchange of zeolitic Brønsted acid sites (BAS) with cations from metal-oxides plays a pivotal role in the propagation of hydrocarbon pools (HCP) during CO2 hydrogenation. We estimated the likelihood of cationic species migration from different oxides-In2O3, ZnZrOx, Cr2O3 and their exchange with BAS by computing metal vacancy formation energies. Accordingly, we integrated metal-oxides and SAPO-34 at nanoscale proximity (~1400 nm), to probe the propensity of the cations to exchange with BAS. To assess the influence of ion-exchange on HCP, we measured propylene-to-ethylene (indicates relative propagation of olefin-to-aromatic cycles) and paraffin-to-olefins ratios, which revealed that Inδ+ species inhibited HCP propagation, Znδ+ species enhanced hydrogen transfer, and Crδ+ species did not influence HCP. Combining reactivity data with ammonia temperature programmed desorption, occluded hydrocarbon analysis, 13C solid-state nuclear magnetic resonance (ssNMR) and X-ray photoelectron spectroscopy analysis (XPS), we provide insights into the influence of ion-exchanged species on HCP for rational integration of bifunctional catalysts.
Pulsed-Bed Column Adsorption for Triclosan Removal Using Macadamia Nut Shell Activated Carbon
Authors: Yimrattanabovorn Jareeya , Phalaiphai Mananya , Nawong Siriwan
Published: June 2024

Triclosan (TCS), a common antibacterial agent found in numerous personal care products, has been detected in wastewater and surface water and is now of significant environmental concern due to its health impacts. To mitigate this issue, various treatment methods have been explored. This study investigated the efficacy of Macadamia nut shell activated carbon (MAC) as an economical adsorbent for triclosan removal. A pulsed-bed column adsorption technique was applied to enhance adsorption capacity and prolong the operational lifespan of the column. Batch experiments were conducted to explore various parameters and adsorption capacity. Column experiments were carried out to investigate breakthrough curves and various associated parameters. In batch experiments, MAC exhibited a high TCS adsorption capacity of 119.05 mg/g, and optimal adsorption conditions were determined. Adsorption kinetics followed the pseudo-second-order model, and equilibrium data were well-fitted by both the Langmuir and Freundlich isotherm models. A pulsed-bed column adsorption showed superior performance compared to a fixed-bed column under specific conditions (flow rate: 10 mL/min, TCS initial concentration: 60 mg/L, bed column height: 10 cm) and removal bed height of only 6 cm, successfully enhancing TCS adsorption capacity to 53.40 mg/g and extending the operational lifespan of the column to 5,280 minutes. Adapting pulsed-bed columns for TCS removal from wastewater in the personal care product industry led to the extension of column life with increased adsorption capacity and minimized the use of adsorbents as a practical and environmentally friendly method. Doi: 10.28991/CEJ-2024-010-05-019 Full Text: PDF
Hidalgo: desafíos del desarrollo
Authors: Gaona Rivera Elías , Vázquez Rojas Angélica María , Rodríguez Juárez Eduardo
Published: June 2024

El estado de Hidalgo es una región de grandes contrastes, pues en él coexisten zonas marginadas y pobres con gran rezago social en: educación, salud, servicios básicos y espacios en la vivienda; tales son los casos de los municipios de: Xochiatipan, Yahualica, Tepehuacán de Guerrero, Huehuetla y Tianguistengo, donde su población vive en extrema pobreza. Por otro lado, tenemos a municipios con índice de desarrollo humano muy alto: Mineral de la Reforma, Pachuca de Soto, Mineral del Monte, Tizayuca y Tepeapulco, los cuales tienen un elevado nivel de vida en comparación con los municipios señalados más arriba, dado que su índice de desarrollo humano supera al promedio estatal y al nacional, cuyos índices son: 0.723 y 0.743, respectivamente.
La Investigación Social en México, 2012. Tomo I
Authors: Serrano Aviles Tomas
Published: June 2024

Las sociedades autodefinidas como modernas han planteado como fin teleológico una serie de metas de corte político, económico y social con la finalidad de construir paradisiacos estadios de armoniosa convivencia social. En este ejercicio, que el proceso de la Ilustración inauguró, se privilegiaron una serie de condiciones unívocas del ser moderno: Hombre, blanco, heterosexual, occidental, con capacidades físicas promedio, capaz de trabajar, sano y autoresponsable de su devenir; construyendo con ello márgenes precisos de adscripción y selección.
Studying the Place of Transcendental Ideals and Human Instincts in Modern Psychology: An Insight into the Alternative Discourse of Mohammad Rafi-ud-Din
Authors: Shaukat Muhammad Awais , Ahmad Humaira
Published: June 2024

The integration of psychological and natural sciences is an ongoing process that aims to understand the human mind in the context of the natural world. Rafi-ud-Din has made significant contributions to this field with his concept of human nature and psychology. He argues that the urge for ideals is the real, ultimate, and sole dynamic power of human actions, and that it finds its roots not in instincts but in something transcendental and metaphysical. He describes man as a spiritual and moral self that has innate knowledge of good and evil, and builds his own discourse to describe human nature in the light of the Qur’ān. He also addresses the influential theories of Marx, Freud, Adler, and MacDougall at length and critiques the ideas that view human nature as primarily driven by instincts, arguing that this view reduces man to the status of a social animal and ignores the spiritual and moral dimension of human existence. His alternative discourse on the role of instincts in human psychology and the place of transcendent ideals in understanding man offers a unique perspective on this topic, and his work is an important contribution to the ongoing debate on the integration of psychological and natural sciences. This paper aims to study the ideas and approaches of Rafi-ud-Din about Human Nature and his efforts to refute the thoughts of modern thinkers.
Effectiveness of SMOTE-ENN to Reduce Complexity in Classification Model
Authors: Riantika Ines , Sartono Bagus , Anwar Notodiputro Khairil
Published: June 2024

A failure to produce classification models with high performance might be caused by the dataset's characteristics, such as the between-class overlapping and the class imbalance. The higher the data complexity, the more complicated it is for the algorithm to find good models.  Combining the issues of class imbalance and overlapping would make the problem more challenging. To deal with this problem, this research implemented a hybrid class-balancing technique named SMOTE-ENN. This technique adds observations to the minority class to balance the class frequencies.  After that, it removes some observations to reduce the degree of overlapping.  The research revealed that SMOTE-ENN succeeds in doing that.  We employed a random forest method to evaluate it. In 28 out of 46 cases we investigated, the new datasets generated by SMOTE-ENN could produce models with higher accuracy.
The exploration of academic staff’s perceptions of the concept of curriculum decolonization in the selected Eastern Cape TVET college
Authors: Ngcobo Philasande , Khoza Samuel Dumazi
Published: June 2024

This study aimed to explore the perceptions of academic staff on the concept of curriculum decolonization in a selected technical and vocational education and training (TVET) college in Eastern Cape Province. South Africa has been confronted with calls for curriculum decolonization and at some point, students all over the country decided to embark on a nationwide protest asking for the decolonization of the curriculum in the institutions of higher learning between 2015 and 2016 through the #feesmustfall movement. The study focused on one Eastern Cape TVET college as an institution of higher learning as a case study. A qualitative approach was adopted, and an interpretive paradigm was employed. There are about eight TVET colleges in Eastern Cape Province offering different courses. The researcher purposively selected two lecturers from each of the five campuses, one assistant director academic and one deputy principal academic to get to a sample size of 12. Critical theory guided this investigation. Data was analysed thematically. The study revealed that some academics do not know what decolonization all is about. There is no formal involvement of lecturers, when it comes to the process of curriculum decolonization at the said TVET college, however, there are engagements on general perspectives about transformation in TVET college sector. The study recommends that TVET colleges should develop a policy on curriculum decolonization. TVET colleges should form a committee that will look at matters of curriculum transformation, which should be inclusive of lecturers, students, managers, and relevant external expects of curriculum transformation.
Framing pre-service teacher preparation in Africa from global STEM education practices
Authors: Mutseekwa Christopher , Dzavo Joseph , Musaniwa Onias , Nshizirungu Gabriel
Published: June 2024

Purpose: This study seeks to review the literature on contemporary science, technology, engineering, and mathematics (STEM) education practices to frame approaches that can be used to prepare STEM pre-service teachers.

Design/methodology: This study used a systematic literature review guided by PRISMA 2020 statement. Following some eligibility criteria 79 studies were selected for synthesis. Data were analysed qualitatively, and Excel spreadsheet was used for the quantitative aspects.

Findings: This synthesis revealed diversity in the conceptualization of STEM education. Despite a lag in global STEM education research, countries such as South Africa and Tanzania have published research areas like STEM education practices, STEM teacher education, and technology adoption for STEM education. The synthesis also showed that aspects of policy, instruction, STEM-teacher professional development, STEM teacher education approaches, student activities, and the nature of support for STEM education are important considerations for developing effective models for framing pre-service teacher preparation.

Originality/value: This study is the original work of the researchers. The study draws from global STEM education practices and assesses the geographical distribution of literature on STEM teacher education practices in African countries to frame a six-point approach that can be used to enhance effective STEM teacher education practices.
UN Peacekeeping Operations Transition in Sierra Leone and Liberia: Analyzing the Grey Zones of the Peacekeeping-Peacebuilding Nexus
Authors: Zaamoun Hind , Sempijja Norman
Published: June 2024

ABSTRACT: This study falls under the scope of the recent debate around UN peacekeeping transitions and exit strategies and highlights a critical gap in understanding the design and conceptualization of these strategies, especially for the long run as post-conflict societies consolidate peace. Using Liberia and Sierra Leone as case studies, the research aims to remedy the empirical gap and shed light on the complexities of framing UN transitions and exit strategies. A central argument posited in this study is that effective management of the entanglement between peacekeeping and peacebuilding is pivotal for enduring success in transition processes. Key contextual elements influencing this management include early planning and initiation of peacebuilding, coordination and integration with local actors, and alignment of benchmarks and needs with all stakeholders before concluding missions. The study applies a social constructivist perspective to examine the different trajectories both Liberia and Sierra Leone have taken in managing their transitions. This article uses qualitative research methods with data drawn from primary and secondary sources .
Innovative approach to develop a thermal management system for a battery electric vehicle
Authors: Pranav Hari Raja Dhamodharan
Published: June 2024

Nowadays all the automotive OEMs were investing huge amount of dollars to develop an innovative technology to handle the thermal management system of their battery electric vehicle (BEV) and hybrid electric vehicle (HEV) . Lots of techniques were used to develop this thermal management system (TMS) by investing huge amount of man hours . In this paper an innovative is handled to understand the available available possible ways to achieve a cost optimized TMS for a HEV and BEV. This is a very basic, but efficient methodology which leads to provide an enhanced system to balance the cost and achieve the customer requirements. The pugh DFSS methodology is used to compare,analyze and evaluate using the simulation techniques. Going forward this proven solution can be implemented in the real time vehicles.
The impact of malnutrition on secondary diabetes and calcific pancreatitis: A comprehensive review
Authors: Ashraf Soliman  , Fawzia Alyafei  , Nada Soliman  , Sohair Elsiddig  , Nada Alaaraj  , Noor Hamed  , Shayma Ahmed
Published: June 2024

Introduction: Malnutrition in low- and middle-income countries significantly impacts the development of secondary diabetes and calcific pancreatitis. Aim and Methods: This review summarizes the prevalence, characteristics, and findings from key studies over the past decade on the link between malnutrition and secondary diabetes, focusing on protein-deficient pancreatic diabetes (PDPD) and fibro-calculous pancreatic diabetes (FCPD). A comprehensive literature search was conducted in PubMed, Scopus, and Google Scholar for articles published between 1995 and 2023. Studies included were peer-reviewed articles focusing on the link between malnutrition and secondary diabetes, conducted in LMICs, and discussing the prevalence, clinical characteristics, and outcomes of PDPD and FCPD. Both observational and interventional studies were considered. Results: The review of studies revealed several key findings: · PDPD is characterized by lower C-peptide levels and varied responses to glibenclamide post-nutritional rehabilitation. · FCPD patients show rapid calcification, diminished exocrine and beta-cell function, and more severe exocrine deficiency compared to PDPD. · Both PDPD and FCPD patients often present with lower BMI and significant renal involvement. · Recent studies indicate improved nutritional status and prognosis of FCPD patients with enhanced medical care. · Insulin-requiring diabetes in Ethiopia is strongly linked with poor education, poverty markers, and childhood malnutrition. · Lean diabetes, linked to childhood malnutrition, is characterized by low-normal BMI, early onset, and rapid beta-cell failure. Discussion: The development of diabetes following early malnutrition can be attributed to several interconnected mechanisms involving metabolic, endocrine, and epigenetic factors. Early nutritional intervention trials are crucial to prevent glucose abnormalities and diabetes later in life. Studies highlight that improving early-life nutrition can enhance beta-cell function, reduce insulin resistance, and mitigate long-term metabolic dysfunction. Lean diabetes, linked to childhood malnutrition, presents unique challenges but can be addressed through targeted nutritional support. Conclusion: The review underscores the significant impact of malnutrition on the development of secondary diabetes and calcific pancreatitis in LMICs. Addressing malnutrition through early nutritional interventions is crucial to mitigate the risk of chronic conditions and improve metabolic health outcomes. Continued research and targeted public health strategies are essential to break the cycle of malnutrition and disease in vulnerable populations.
A Rare Manifestation of Migrated Intrauterine Contraceptive Device: A Case Study Highlighting Symptoms and Ultrasound Detection
Authors: Augustina Badu-Peprah  , Theophilus Kofi Adu-Bredu  , Daniel Asante-Mante  , Kwame Asiedu Danso  , Yaw Boateng Mensah
Published: June 2024

Ultrasonography is a widely used and cost-effective imaging modality, but its effectiveness can be operator dependent. We present the case of a 29-year-old para 3A woman who experienced intermittent low abdominal pains and skin rash following the insertion of a copper-T intrauterine contraceptive device (IUCD). Ultrasound, performed by an experienced operator, was crucial in diagnosing a migrated IUCD with adnexal and skin complications. This case highlights the importance of skilled ultrasound operators in detecting migrated IUCDs and associated complications.
Phage therapy for intracellular MRSA infections and navigating transduction risks
Authors: Aasima Hassan  , Zainab Ibrar  , Neha Kishwar  , Kiran Chaudhary  , Aasma Nasim
Published: June 2024

In response to escalating antibiotic resistance, Methicillin-resistant Staphylococcus aureus (MRSA) infections, especially chronic intracellular cases, pose a persistent challenge. Phage therapy offers a promising alternative, targeting intracellular MRSA effectively. This review explores phage therapy's mechanisms, efficacy, challenges, and future prospects, with a focus on transduction risks. The review details phage therapy's intricate mechanisms against MRSA, highlighting dynamic phage-bacterial interactions within host cells. Evidence and case studies underscore transduction risks, including genetic element transfer and antibiotic resistance acquisition. Studies demonstrating phage therapy's efficacy against intracellular MRSA stress the need for tailored strategies and innovative approaches for enhanced phage access and efficacy within cells. Challenges like phage resistance and cell penetration limitations are examined, with proposed solutions to improve intracellular phage activity. Cutting-edge technologies such as whole-genome sequencing and single-cell analysis are discussed for monitoring and controlling transduction events. Collaboration among researchers, healthcare professionals, and regulators is emphasized to establish robust guidelines and address biosecurity concerns in phage therapy applications.
Concurrence of plants and its representation in Indonesian proverbs
Authors: Wijana I Dewa Putu
Published: June 2024

This brief article deals with the concurrence of plants or its parts and its representations in Indonesian proverbs. The data used are mostly extracted from Indonesian proverb books, and ones found in proverbs of other languages. First, the data are classified based on plants or parts of plant possibly concurred. Later, the investigation is directed toward the various possibility the combination might represent. Through careful analysis, it is finally found that the plants or parts of the plants to be combined can be between different plants, parts of the same plants, one plant and its parts, parts and different plants, and parts of different plants. Plants or parts of plants to be combined are perceived as: to have the same quality for representing something hard or impossible to change, something must be committed by both parties, the same destiny to be experienced, or how should someone to behave; the different quality of plants or parts of the plant is used to represent unexpected thing (better or worse) to happen, not easy to give up and always depend on something available, could differentiate between good and bad matters, to use the worse quality things first before the better ones, imbalance competition, ability and sincerity to accept the good and bad aspect of things; one plant or parts of the plant are older (coming out earlier) or younger (coming out later) than the others to represent the difficulties for the older people to change, any occasion follows cause and effect law, the new comers usually should or could not drive out or defeat the natives; and phonological representation to show that sometimes the proverbs are created on the basis of aesthetic achievements instead of merely on metaphorical similarities.
O perfil socioeconômico dos discentes de Licenciaturas na Universidade Federal de Mato Grosso do Sul (UFMS), Campus do Pantanal (CPAN)
Authors: Rückert Fabiano Quadros , Felipe Dartagan Maropo Teixeira de Castro  , Gonçalina Francisca de Oliveira Martta
Published: June 2024

O artigo analisa o perfil socioeconômico de 120 discentes matriculados em cursos de Licenciatura na Universidade Federal de Mato Grosso do Sul (UFMS), no Campus do Pantanal (CPAN). Estes discentes representam uma amostra dos acadêmicos que cursam licenciaturas presenciais, na fronteira oeste do Brasil. O conjunto de participantes da pesquisa é composto por discentes que aceitaram responder um questionário disponibilizado na Plataforma Google Forms, no período entre 01 de agosto e 30 de setembro de 2023. O questionário contemplou aspectos como gênero; raça; faixa etária; situação laboral; composição familiar dos discentes; e também registrou informações sobre a trajetória escolar e as suas expectativas em relação à formação recebida no Ensino Superior. A partir dos dados coletados e com o auxílio de pesquisas que abordam o processo de democratização do Ensino Superior, o artigo busca ampliar o conhecimento existente a respeito dos discentes de Licenciaturas que residem na fronteira Brasil/Bolívia.
Determining the relationship between physical activity and intuitive eating and mindful eating in university students
Authors: Mert Biberoğlu Fatma , Güven Sanem , Yenipınar Zeynep Güler
Published: June 2024

In this study, it was aimed to determine the relationship between physical activity and intuitive eating (IE) and mindful eating (ME) in university students. The “International Physical Activity Short Form”, “Mindful Eating Test (MET)” and “Intuitive Eating Scale (IES)” were applied by questioning the demographic characteristics, anthropometric measurements, health information and nutritional habits of 255 university students studying in Health and Sports sciences. Among the students whose mean age is 20.34±2.06, 86.7% of the students who are in health science are female, and 67.7% of them, who are in sports sciences are male (p<0.05). Students (51.4%) with normal Body Mass Index (BMI) consume three main meals and go on a diet for aesthetic reasons. Eating discipline (ED), emotional eating (EE), and intuitive eating total (IET) scores are higher in females, while control of eating (EC) scores are higher in males (p<0.05). Intuitive eating total score, reliance on hunger and satiety cues (RHSC), unconditional permission to eat (UPE) and EC cores are positively related to BMI. Students who are physically inactive have higher IET score, RHSC, body-food choice congruence, focusing and ED, and those who do adequate physical activity have higher eating control scores (p<0.05). Mindful eating total score and sub-dimensions are positively correlated with the score of all sub-dimensions except UPE, which is one of the sub-dimensions of IE (p<0.05). In addition, as the UPE score increases, the total scores of disinhibitions, ED, focusing, interference, EE, and ME decrease (p<0.05). In conclusion, ME and IE are positively related to each other. It is understood that adequate and balanced nutrition along with being physically active at the same time is quite important for younger individuals to be healthier.
Innovation in the dairy industry: forecasting cow cheese production with machine learning and deep learning models
Authors: Gür Yunus Emre
Published: June 2024

This study focuses on the use of deep learning and machine learning models to forecast cow cheese production in Turkey. In particular, our research utilizes the LSTM (long short-term memory) model to forecast cow cheese production for the next 12 months by extensively utilizing deep learning and machine learning techniques that have not been applied in this field before. In addition to LSTM, models such as GRU (Gated Recurrent Unit), MLP (Multi-Layer Perceptron), SVR (Support Vector Regression), and KNN (K-Nearest Neighbors) were also tested, and their performances were compared using RMSE (Root Mean Square Error), MSE (Mean Squared Error), MAE (Mean Absolute Error), MAPE (Mean Absolute Percentage Error), and (Coefficient of Determination) metrics. The findings revealed that the LSTM model performed significantly better than the other models in terms of RMSE, MSE, MAE, and MAPE values. This result indicates that the LSTM model provides high accuracy and reliability in forecasting cow cheese production. This achievement of the model offers important applications in areas such as supply chain management, inventory optimization, and demand forecasting in the dairy industry.
Relacje między miłością, posiadaniem dzieci a stosowaniem używek
Authors: Samerdak Kamila
Published: June 2024

Przeprowadzone badanie na celu miało sprawdzenie, czy osoby będące w związkach romantycznych mają wysokie poziomy czynników miłości według Sternberga czyli intymność, namiętność i zaangażowanie (Sternberg, 1986). Dodatkowymi czynnikami uwzględnionymi w badaniach są ilość dzieci z obecnym partnerem oraz korzystanie z używek i uzależnienia. Badanie przeprowadzone zostało na polskiej populacji, zróżnicowanej płciowo i dobranej losowo. Wyniki pokazują, że częste spożywanie alkoholu koreluje z niższym poziomem intymności w relacji. Według dokonanej analizy, osoby mające przeszłość z uzależnieniami osiągają niższy wynik namiętności w związkach, osoby często spożywające alkohol osiągają wyniki wyższe. Częste używanie alkoholu oraz uzależnienia znacząco obniżają zaangażowanie w relację. Replikacja tezy Sorokowskiego o wpływie miłości i ilości dzieci potwierdza otrzymane przez niego wyniki – w polskiej populacji występuje istotna zależność między zaangażowaniem, a ilością dzieci posiadaną przez parę.
It’s the Little Things in Life: Enjoyment of Different Types of Personal Projects
Authors: Hill Taylor , Coughlan Emma , Mackinnon Sean P.
Published: June 2024

Many positive psychology interventions aim to improve happiness through engagement in simple and intentional everyday activities that offer intrinsic rewards. Personal projects are personally relevant goal-directed activities that take place over an extended period of time, and are a way to study the intentional pursuit of happiness. This exploratory study identifies the types of projects that people engage in and which project dimensions predict hedonic well-being (enjoyment). Students (N = 327) and community participants completed the Personal Project Analysis in a cross-sectional survey. Two coders thematically coded projects into seven types. We used linear mixed models to identify which project types and dimensions uniquely predict enjoyment. People engaged in various types of activities (7 project types) which were enjoyed to different extents (relationship projects were most enjoyable while household maintenance were least enjoyable) and tend to experience greater enjoyment when projects encourage autonomy, control, likelihood of success, progress, absorption, low difficulty, and low challenge. Knowledge on which activity characteristics are linked to well-being can inform tailored positive psychology programming. Overall, people tend to find activities which are relatively easy and where they make a lot of progress more enjoyable, indicating simple daily activities are one way to intentionally prioritize daily well-being.
The "Naturalistic Free Recall" dataset: four stories, hundreds of participants, and high-fidelity transcriptions
Authors: Raccah Omri , Chen Phoebe , Gureckis Todd Matthew , Poeppel David , Vo Vy
Published: June 2024

The "Naturalistic Free Recall" dataset provides transcribed verbal recollections of four spoken narratives collected from 229 participants. Each participant listened to two stories, varying in duration from approximately 8 to 13 minutes, recorded by different speakers. Subsequently, participants were tasked with verbally recalling the narrative content in as much detail as possible and in the correct order. The dataset includes high-fidelity, time-stamped text transcripts of both the original narratives and participants' recollections. To validate the dataset, we apply a previously published automated method to score memory performance for narrative content. Using this approach, we extend effects traditionally observed in classic list-learning paradigms. The analysis of narrative contents and its verbal recollection presents unique challenges compared to controlled list-learning experiments. To facilitate the use of these rich data by the community, we offer an overview of recent computational methods that can be used to annotate and evaluate key properties of narratives and their recollections. Using advancements in machine learning and natural language processing, these methods can help the community understand the role of event structure, discourse properties, prediction error, high-level semantic features (e.g., idioms, humor), and more.
Visual Memory for Natural Scenes
Authors: Guo Xiaohan (Hannah) , Bainbridge Wilma A.
Published: June 2024

Humans have been exposed to a continuous stream of scenes since the first day of life. Through constant processing and encoding of scenes, the human brain develops scene knowledge that aids current scene understanding and guides future scene memory and decision-making. In this chapter, we will discuss how humans’ scene memories and understandings are shaped by (1) scene-level properties that are intrinsic to a scene or that arise through comparisons, (2) observer-level properties, such as prior knowledge, cognitive states, and ages, and (3) new knowledge generated through the interactions between scene- and observer level information.
Survey Sampling Design in Wave 1 of the Global Flourishing Study
Authors: Padgett R. Noah , Cowden Richard , Chattopadhyay Manas , Han Ying , Honohan John , Ritter Zacc , Srinivasan Rajesh , Johnson Byron R. , VanderWeele Tyler J.
Published: June 2024

The Global Flourishing Study (GFS) is an international collaboration to develop a publicly accessible data resource to promote global research on human flourishing. These data include over 200,000 participants from 22 geographically and culturally diverse countries and one territory designed to be nationally representative of the adult population. The GFS is intended as a longitudinal panel study with recruitment and empanelment for Wave 1 occurring between April 2022 and December 2023. Future waves of data collection will invite participants to complete a survey annually. The annual survey covers a robust set of measures on well-being, health, social, economic, political, religious, spiritual, psychological and demographic variables. The current paper describes the sampling methodology and weighting approaches used to project the samples to be nationally representative. Details are provided on interviewer training and data collection, probability and non-probability samples, creating weights, design effects, and future data collection stages.
Measuring Financial Efficiency of Public Enterprises in Nepal
Authors: Khadka Narayan
Published: June 2024

Not Available.
An Analysis of the Determinants of Inflation in Nepal
Authors: Khatiwada Yuba Raj
Published: June 2024

Not Available.
Nutritional Disparities in Urban Aging: Ethnicity as culprit for Malnutrition in Ratnanagar Municipality
Authors: Subedi Sunita , Malla Ashesh , Giri Bibek , Adhikari Kishor , Subedi Shankar Nand , Sigdel Ramesh
Published: June 2024

INTRODUCTION: Nutritional disparities in urban aging have emerged as a critical concern globally. As the aging population grows and urbanization accelerates, understanding the drivers of malnutrition among older adults in urban areas, especially across diverse ethnic groups becomes increasingly urgent. The study addresses the critical concern of malnutrition among older adults in urban areas, focusing on the influence of ethnicity on nutritional disparities.
MATERIALS AND METHODS: An analytical cross- sectional study was conducted among 341 elderly people aged above 60 years from March 2023 to August 2023 in Ratnanagar municipality of Chitwan. A systematic random sampling technique was employed to select participants from each ward. Face to face interview technique and anthropometric assessment was used in collecting data using semi-structured questionnaire comprising socio-demographic characteristics including ethnicity, life-style factors, dietary factors, functional status and nutritional status. Data analysis was performed using the Statistical Program for Social Sciences version 26.
RESULTS: The mean age of the participants was 69.86 years (SD = 7.72), with a range from 61 to 99 years. Of 317 participating elderly people, the prevalence of malnutrition and risk of malnutrition was 27.44% and 55.84% respectively. Dalit (50% malnourished, 50% at risk); Janajatis (31.50% malnourished, 57.48% at risk); Madeshi (33.33% malnourished, 50% at risk) and Muslim (20% malnourished, 60% at risk) respondents, categorized as disadvantaged, showed higher proportions of malnutrition or at-risk status; while Brahmin/Chhetri respondents considered advantaged, exhibited comparatively lesser proportion of malnutrition [1.79 (95% CI: 1.06-3.03)]. Likewise, disadvantaged ethnic group exhibited a significant AOR of 1.46 (95% CI: 1.05-2.89) for being at risk, compared to advantaged group.
CONCLUSIONS: There were significant disparities in nutritional status among older adults in Ratnanagar Municipality, with disadvantaged ethnic groups being particularly vulnerable to malnutrition. The findings of this study have important implications for public health policy and practice in Nepal.
STUDY SOME TAXONOMIC ASPECTS OF THE TWO SPECIES Limonium meyeri (Boiss.) Kuntze AND Limonium thouinii (Viv.) Kuntze, IN IRAQ
Authors: AL-Amery Shaemaa Muhi Hasson , Al-Qaraawi Hanan Ahmed Hadi , Abu-Serag Nidaa Adnan , Jassim Yazi Abdullah
Published: June 2024

The research aims to separate two species of the genus Limonium (Limonium meyeri and Limonium tuinii) using some Morphological and anatomical characters as taxonomic evidence. The current research included the study of the micro-characteristics of pollen grains and some anatomical characteristics of the stem and leaf using the light and Scanning electron microscope for separation of the species. The attributes of pollen grains (the size of the pollen, the germinating aperture width, and the surface ornamentation). The average length of the polar axis in the polar view reached 45 µm in L. meyeri and 35 µm in L. thouinii. In addition to the variation in the width of the germination aperture width, which was 17.5 µm in L. meyeri and 7.5 µm in L. thouinii. as well as the variations in the characteristics of the epidermal cells and the cross-section of the stems, are of good taxonomic importance to separate the two species. The research confirmed that the micro-characteristics of pollen grains and the anatomical characteristics are of complementary taxonomic importance to the morphological traits in separating genera and species.
Keywords: Plumbaginaceae; pollen grains; anatomy of the stem.
 
Aspectos taxonômicos das espécies vegetais Limonium meyeri (Boiss.) Kuntze e Limonium tuinii (Viv.) Kuntze, no Iraque
 
RESUMO: Esta pesquisa objetivou separar duas espécies do gênero Limonium (Limonium meyeri e Limonium tuinii) utilizando alguns caracteres morfológicos e anatômicos como evidência taxonômica. A presente pesquisa incluiu o estudo das micro características dos grãos de pólen e algumas características anatômicas do caule e da folha utilizando o microscópio óptico e eletrônico de varredura para separação das espécies. Os atributos dos grãos de pólen (tamanho do pólen, largura da abertura de germinação e ornamentação da superfície). O comprimento médio do eixo polar na visão polar atingiu 45 µm em L. meyeri e 35 µm em L. tuinii. Além da variação na largura da abertura de germinação, que foi de 17,5 µm em L. meyeri e 7,5 µm em L. tuinii. As variações nas características das células epidérmicas e na secção transversal dos caules, foram importantes caracteres taxonômicos para separar as duas espécies. A pesquisa confirmou que as micro características dos grãos de pólen e as características anatômicas são de importância taxonômica complementar às características morfológicas na separação de gêneros e espécies.
Palavras-chave: Plumbaginaceae; grãos de pólen; anatomia do caule.