bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrated Value Engineering and Life Cycle Cost Modeling for HVAC System Selection
Authors: Al-Ghamdi Mohammed A. , Al-Gahtani Khalid S.
Published: February 2022

Selecting a suitable heating, ventilation, and air-conditioning (HVAC) system is critical, because it impacts a building’s life cycle cost (LCC). Several factors affect the selection decision, such as quality, buildability, internal and external building appearance, HVAC size and weight, and LCC. These criteria are difficult to measure, as they are not based on agreed measurement units. Another challenging factor in the selection process is assessing the building’s function/performance and determining its HVAC needs. Currently, the decision depends mostly on expert knowledge, and there is no agreed-upon systematic method to follow. This paper aims to develop a systematic model for selecting HVAC systems based on the value engineering (VE) concept. The model identified fourteen criteria based on an agreed standard test for objective criteria and a typical evaluation for subjective criteria. These HVAC criteria were assessed using a combination of the AHP, pairwise, function analysis system (FAST), and Monte Carlo techniques. As a result, a complete model was developed to enhance the selection process, programmed within the building information modeling (BIM) environment platform. Several HVAC experts were interviewed and more than twenty expert opinions were collected to validate the model. In addition, a case study building in Riyadh, Saudi Arabia, was implemented using the programmed HVAC selection model for validation purposes. The programmed model can significantly facilitate the selection process for designers.
Direct and Indirect Effects of Social Support and School Social Capital on the Academic Success of 11–19-Year-Old Students Using Distance Learning
Authors: Mieziene Brigita , Emeljanovas Arunas , Jusiene Roma , Breidokiene Rima , Girdzijauskiene Sigita , Sabaliauskas Stanislav , Buzaityte-Kasalyniene Jolita , Budiene Virginija , Eiliakaite Indre , Speicyte-Ruschhoff Erika , Babkovskiene Edita , Zvirdauskas Dainius , Kawachi Ichiro
Published: February 2022

In the context of current changes in the education process due to the pandemic, the main aims of this study were to highlight social capital factors within the school community that are associated with better students’ outcomes in the context of distance learning. This study was a cross-sectional population-based study. The research sample consisted of 1483 students, whose ages varied from 11 to 19 years old (56.9% were girls). Academic success in this study was measured in terms of average grade and students’ perception of their learning process or outcomes by six single items. A Five-item WHO-5 questionnaire was used to measure students’ psychological well-being. Social capital was measured in terms of relationship, trust, reciprocity, and communication within different social contexts in the school community in total by 16 items. School social capital and social support scales were developed from these items. Students’ gender and age were also taken into consideration. The research results show that although social capital from parents and peers also matters, the relationship with teachers emerges as the main and the most important resource in supporting positive attitudes and outcomes in to learning (std.β varied from 0.116 to 0.439). The results also show that higher psychological wellbeing is associated with higher perceived school social capital (std.β 0.260) and social support (std.β 0.326) and mediates the effects of the latter two for better academic success outcomes. The findings also highlight the importance of close and trusting social ties, especially between students and their teachers as well as parents for better learning outcomes in times of crises and in the context of distance learning. The study results prove that social support and social capital at school are essential factors for sustainable psychological development. The results presumably support the idea that the school is sustainable if it is developing as an ecosystem not solely aimed at academic outcomes. The results of the current study may aid policymakers and practitioners in developing interventions, policies and practices that focus resources where they will have the greatest benefit.
Exploration of the Structural Asymmetry Induced by the Intrinsic Flexibility of HIV-2 Protease
Authors: Badel Anne , Breuil Laëtitia , Laville Pierre , Regad Leslie
Published: February 2022

HIV-2 protease (PR2) is a homodimer targeted by drugs in the treatment of HIV-2 infections. This dimer is often considered symmetric. However, exploration of crystallographic structures showed that the two chains of PR2 exhibit different conformations. This study presents the first analysis of the structural asymmetry of PR2 induced by its intrinsic flexibility. We followed the structural asymmetry of PR2 throughout a molecular dynamics (MD) simulation of 1 microsecond. To do so, we quantified the global and local structural asymmetries of 1001 structures extracted from the MD simulation using the root mean square deviation (RMSD) between the two chains in each structure. We then analyzed the links between global and local asymmetry and PR2 flexibility. Our results showed that the global asymmetry of PR2 evolves over time and that it is not explained by the asymmetry of only one region of PR2. We noted that the most flexible regions of PR2 are the most asymmetric regions, revealing that the structural asymmetry of a region is induced by its intrinsic flexibility. Using multivariate analysis methods, we identified six asymmetric profiles varying from structures exhibiting weak asymmetry to structures with extreme asymmetry in at least eight different regions. The analysis of transitions between the different profiles in the MD simulation showed that two consecutive structures often exhibit similar asymmetric profiles, revealing small deformations. To conclude, this study provides insights which help to better understand PR2’s structure, dynamics, and deformations.
Improving Functional Connectivity in Developmental Dyslexia through Combined Neurofeedback and Visual Training
Authors: Taskov Tihomir , Dushanova Juliana
Published: February 2022

This study examined the effects of combined neurofeedback (NF) and visual training (VT) on children with developmental dyslexia (DD). Although NF is the first noninvasive approach to support neurological disorders, the mechanisms of its effects on the brain functional connectivity are still unclear. A key question is whether the functional connectivities of the EEG frequency networks change after the combined NF–VT training of DD children (postD). NF sessions of voluntary α/θ rhythm control were applied in a low-spatial-frequency (LSF) illusion contrast discrimination, which provides feedback with visual cues to improve the brain signals and cognitive abilities in DD children. The measures of connectivity, which are defined by small-world propensity, were sensitive to the properties of the brain electrical oscillations in the quantitative EEG-NF training. In the high-contrast LSF illusion, the z-NF reduced the α/θ scores in the frontal areas, and in the right ventral temporal, occipital–temporal, and middle occipital areas in the postD (vs. the preD) because of their suppression in the local hub θ-network and the altered global characteristics of the functional θ-frequency network. In the low-contrast condition, the z-NF stimulated increases in the α/θ scores, which induced hubs in the left-side α-frequency network of the postD, and changes in the global characteristics of the functional α-frequency network. Because of the anterior, superior, and middle temporal deficits affecting the ventral and occipital–temporal pathways, the z-NF–VT compensated for the more ventral brain regions, mainly in the left hemispheres of the postD group in the low-contrast LSF illusion. Compared to pretraining, the NF–VT increased the segregation of the α, β (low-contrast), and θ networks (high-contrast), as well as the γ2-network integration (both contrasts) after the termination of the training of the children with developmental dyslexia. The remediation compensated more for the dorsal (prefrontal, premotor, occipital–parietal connectivities) dysfunction of the θ network in the developmental dyslexia in the high-contrast LSF illusion. Our findings provide neurobehavioral evidence for the exquisite brain functional plasticity and direct effect of NF–VT on cognitive disabilities in DD children.
Symmetric Image Encryption Algorithm Based on a New Product Trigonometric Chaotic Map
Authors: Lu Qing , Yu Linlan , Zhu Congxu
Published: February 2022

In the present work, a neotype chaotic product trigonometric map (PTM) system is proposed. We demonstrate the chaotic characteristics of a PTM system by using a series of complexity criteria, such as bifurcation diagrams, Lyapunov exponents, approximate entropy, permutation entropy, time-series diagrams, cobweb graphs, and NIST tests. It is proved that the PTM system has a wider chaotic parameter interval and more complex chaotic performance than the existing sine map system. In addition, a novel PTM based symmetric image encryption scheme is proposed, in which the key is related to the hash value of the image. The algorithm realizes the encryption strategy of one-graph-one-key, which can resist plaintext attack. A two-dimensional coordinate traversal matrix for image scrambling and a one-dimensional integer traversal sequence for image pixel value transformation encryption are generated by the pseudo-random integer generator (PRING). Security analysis and various simulation test results show that the proposed image encryption scheme has good cryptographic performance and high time efficiency.
A Novel Recombinant FAdV-4 Virus with Fiber of FAdV-8b Provides Efficient Protection against Both FAdV-4 and FAdV-8b
Authors: Lu Hao , Xie Quan , Zhang Wei , Zhang Jianjun , Wang Weikang , Lian Mingjun , Zhao Zhehong , Ren Dan , Xie Songhua , Lin Yun , Li Tuofan , Mu Yaru , Wan Zhimin , Shao Hongxia , Qin Aijian , Ye Jianqiang
Published: February 2022

Since 2015, the outbreaks of hydropericardium-hepatitis syndrome (HHS) and inclusion body hepatitis (IBH) caused by the highly pathogenic serotype 4 fowl adenovirus (FAdV-4) and serotype 8 fowl adenovirus (FAdV-8), respectively, have caused huge economic losses to the poultry industry. Although several vaccines have been developed to control HHS or IBH, a recombinant genetic engineering vaccine against both FAdV-4 and FAdV-8 has not been reported. In this study, recombinant FAdV-4 expressing the fiber of FAdV-8b, designated as FA4-F8b, expressing fiber of FAdV-8b was generated by the CRISPR-Cas9 and homologous recombinant techniques. Infection studies in vitro and in vivo revealed that the FA4-F8b replicated efficiently in LMH cells and was also highly pathogenic to 2-week-old SPF chickens. Moreover, the inoculation of inactivated the FA4-F8b in chickens could not only induce highly neutralizing antibodies, but also provide efficient protection against both FAdV-4 and FAdV-8b. All these demonstrate that the inactivated recombinant FA4-F8b generated here can act as a vaccine candidate to control HHS and IBH, and FAdV-4 can be an efficient vaccine vector to deliver foreign antigens.
What Drives the Value of a Shigella Vaccine?
Authors: Hausdorff William P. , Scheele Suzanne , Giersing Birgitte K.
Published: February 2022

The development and licensure of a safe and highly efficacious Shigella vaccine has been a priority in international public health circles for decades and would represent a great scientific achievement. Nonetheless, in the context of increasingly crowded and costly childhood immunization programs, and with a myriad of other new and improved vaccines currently or soon on the market, there is no guarantee that even a highly effective Shigella vaccine would become a priority for adoption and introduction by the low- and middle-income countries that could benefit from it the most. We discuss here some of the major determinants and questions regarding the introduction of Shigella vaccines and the importance of developing a succinct, compelling public health value proposition.
Autochthonous Outbreak of SARS-CoV-2 Omicron Variant in Booster-Vaccinated (3 Doses) Healthcare Workers in Southern Italy: Just the Tip of the Iceberg?
Authors: Loconsole Daniela , Bisceglia Lucia , Centrone Francesca , Sallustio Anna , Accogli Marisa , Dalfino Lidia , Brienza Nicola , Chironna Maria
Published: February 2022

The Omicron variant of concern (VOC), first detected in Italy at the end of November 2021, has since spread rapidly, despite high vaccine coverage in the Italian population, especially in healthcare workers (HCWs). This study describes an outbreak of SARS-CoV-2 Omicron infection in 15 booster-vaccinated HCWs. On 16 December 2021, two HCWs working in the same ward were infected with SARS-CoV-2. The Omicron VOC was suspected due to S gene target failure on molecular testing. Further investigation revealed that 15 (65%) of 23 HCWs attending a social gathering on 13 December were infected with Omicron, as shown by whole-genome sequencing, with a phylogenetic tree suggesting a common source of exposure. Five of these HCWs experienced mild symptoms. A patient with multiple chronic conditions hospitalized in the same ward was also infected by one of the HCWs involved in the outbreak. Despite being booster vaccinated, this patient required ICU treatment. Ten subjects achieved negativity in 10–19 days. The outbreak in booster-vaccinated subjects confirms the high transmissibility and immune evasion of the Omicron VOC. More stringent non-pharmaceutical interventions, administration of booster doses, and genomic surveillance are crucial long-term strategies to mitigate the consequences of the spread of the Omicron VOC.
Propensity-Score-Matched Evaluation of Adverse Events Affecting Recovery after COVID-19 Vaccination: On Adenovirus and mRNA Vaccines
Authors: Son Chang-Sik , Jin Sang-Hyeon , Kang Won-Seok
Published: February 2022

This study aimed to observe adverse events following immunisation (AEFIs) that affected recovery within two weeks after COVID-19 vaccination and investigate their risks in propensity-score-matched populations. Data were collected from 447,346 reports from the VAERS between 1 January 2021 and 31 July 2021. Propensity-score-matched populations were constructed by adjusting for demographic characteristics and 11 underlying diseases in eligible subjects who received 1 of 3 COVID-19 vaccines: 19,462 Ad26.COV2.S, 120,580 mRNA-1273, and 100,752 BNT162b2. We observed that 88 suspected AEFIs (22 in Ad26.COV2.S, 62 in mRNA-1273, and 54 in BNT162b2) were associated with an increased risk of delayed recovery within 2 weeks after COVID-19 vaccinations. Nervous system, musculoskeletal and connective tissue, gastrointestinal, skin, and subcutaneous tissue disorders were the most common AEFIs after COVID-19 vaccination. Interestingly, four local and systemic reactions affected recovery in different vaccine recipients during our study period: asthenic conditions and febrile disorders in Ad26.COV2.S and mRNA-1273; general signs and symptoms in mRNA-1273 and BNT162b2; injection site reactions in Ad26.COV2.S and BNT162b2. Although it is necessary to confirm a causal relationship with COVID-19 vaccinations, some symptoms, including paralysis, allergic disorders, breathing abnormalities, and visual impairment, may hinder the recovery of these recipients.
Modelling SARS-CoV-2 Binding Antibody Waning 8 Months after BNT162b2 Vaccination
Authors: Hatzakis Angelos , Karabinis Andreas , Roussos Sotirios , Pantazis Nikos , Degiannis Dimitrios , Chaidaroglou Antigoni , Petsios Konstantinos , Pavlopoulou Ioanna , Tsiodras Sotirios , Paraskevis Dimitrios , Sypsa Vana , Psichogiou Mina
Published: February 2022

Several lines of evidence suggest that binding SARS-CoV-2 antibodies such as anti-SARS-CoV-2 RBD IgG (anti-RBD) and neutralising antibodies (NA) are correlates of protection against SARS-CoV-2, and the correlation of anti-RBD and NA is very high. The effectiveness (VE) of BNT162b2 in preventing SARS-CoV-2 infection wanes over time, and this reduction is mainly associated with waning immunity, suggesting that the kinetics of antibodies reduction might be of interest to predict VE. In a study of 97 health care workers (HCWs) vaccinated with the BNT162b2 vaccine, we assessed the kinetics of anti-RBD 30–250 days after vaccination using 388 individually matched plasma samples. Anti-RBD levels declined by 85%, 92%, and 95% at the 4th, 6th, and 8th month from the peak, respectively. The kinetics were estimated using the trajectories of anti-RBD by various models. The restricted cubic splines model had a better fit to the observed data. The trajectories of anti-RBD declines were statistically significantly lower for risk factors of severe COVID-19 and the absence of vaccination side effects. Moreover, previous SARS-CoV-2 infection was associated with divergent trajectories consistent with a slower anti-RBD decline over time. These results suggest that anti-RBD may serve as a harbinger for vaccine effectiveness (VE), and it should be explored as a predictor of breakthrough infections and VE.
Nitrogen Transport/Deposition from Paddy Ecosystem and Potential Pollution Risk Period in Southwest China
Authors: Guo Shufang , Yan Tiezhu , Zhai Limei , Yen Haw , Liu Jian , Li Wenchao , Liu Hongbin
Published: February 2022

Nitrogen (N) losses through runoff from cropland and atmospheric deposition contributed by agricultural NH3 volatilization are important contributors to lake eutrophication and receive wide attention. Studies on the N runoff and atmospheric N deposition from the paddy ecosystem and how the agriculture-derived N deposition was related to NH3 volatilization were conducted in the paddy ecosystem in the Erhai Lake Watershed in southwest China. The critical period (CP) with a relatively high total N (TN) and NH4+-N deposition occurred in the fertilization period and continued one week after the completion of fertilizer application, and the CP period for N loss through surface runoff was one week longer than that for deposition. Especially, the mean depositions of NH4+-N in the CP period were substantially higher than those in the subsequent period (p < 0.01). Moreover, agriculture-derived NH4+ contributed more than 54% of the total NH4+-N deposition in the CP period, being positively related to NH3 volatilization from cropland soil (p < 0.05). The N concentrations were higher in the outlet water of ditches and runoff in May than in other months due to fertilization and irrigation. Therefore, to reduce the agricultural N losses and improve lake water quality, it is important to both reduce agricultural NH4+-N deposition from NH3 volatilization and intercept water flow from the paddy fields into drainage ditches during the CP.
Identification of Groundwater Radon Precursory Anomalies by Critical Slowing down Theory: A Case Study in Yunnan Region, Southwest China
Authors: Qiao Zhiyuan , Wang Guangcai , Fu Hong , Hu Xiaojing
Published: February 2022

In this study, we use the critical slowing down (CSD) theory to identify the precursory anomalies of groundwater radon based on the 1000-day continuous data from 8 monitoring stations in Yunnan Province, China during the seismically active period of 1993–1996. The low-frequency and high-frequency information were extracted from raw groundwater radon data to calculate their one-step lag autocorrelation (AR-1) and variance, respectively, in order to identify the precursory anomalies. The results show that the anomaly characteristics can be divided into three categories: sudden jump anomalies, persistent anomalies, and fluctuation anomalies. The highest average seismic recognition rate is 72.78%, based on the high-frequency information’s autocorrelation, while the lowest is 45.08%, based on the low-frequency information’s variance. The crustal activity and the change in hydrogeological conditions are possibly the main factors influencing groundwater radon anomalies in the selected period in the study area. There is a positive correlation between the anomaly occurrence time and epicentral distance when epicentral distance is less than 300 km, which may be related to the seismogenic modes and hydrogeological conditions. This study provides a reference for identifying groundwater radon anomalies before earthquakes by mathematical methods.
A Study on Darcy versus Forchheimer Models for Flow through Heterogeneous Landfills including Macropores
Authors: Winter Roman , Valsamidou Archontoula , Class Holger , Flemisch Bernd
Published: February 2022

Flow through heterogeneous landfills that include macropores may occur under Reynolds numbers higher than those where Darcy’s law is valid. Extensions, such as a Forchheimer approach, may be required to include inertial effects. Our aim is developing predictive models for such landfills that are built from the low-level radioactive waste and debris of dismantled nuclear power plants. It consists of different materials, which after crushing result in a spatially heterogeneous distribution of porous-media properties in the landfills. Rain events or leakage, for example, may wash out radionuclides and transport them with the water flow. We investigate here the water flow and consider an inclusion of macropores. To deal with possibly high velocities, we choose the Forchheimer model and, taking different Forchheimer coefficients into account, compare it to the Darcy model. The focal points of the study are (i) the influence of the macropores on the flow field and (ii) the impact of the choice of the Forchheimer coefficient both on the solution and the computational effort. The results show that dependent on their size, macropores can dominate the flow field. Furthermore, Forchheimer coefficients introducing more inertial effects are associated with considerably higher runtimes.
Removal of Nutrients and Pesticides from Agricultural Runoff Using Microalgae and Cyanobacteria
Authors: Castellanos-Estupiñan Miguel , Carrillo-Botello Astrid , Rozo-Granados Linell , Becerra-Moreno Dorance , García-Martínez Janet , Urbina-Suarez Néstor , López-Barrera Germán , Barajas-Solano Andrés , Bryan Samantha , Zuorro Antonio
Published: February 2022

The use of pesticides in agriculture has ensured the production of different crops. However, pesticides have become an emerging public health problem for Latin American countries due to their excessive use, inadequate application, toxic characteristics, and minimal residue control. The current project evaluates the ability of two strains of algae (Chlorella and Scenedesmus sp.) and one cyanobacteria (Hapalosyphon sp.) to remove excess pesticides and other nutrients present in runoff water from rice production. Different concentrations of wastewater and carbon sources (Na2CO3 and NaHCO3) were evaluated. According to the results, all three strains can be grown in wastewater without dilution (100%), with a biomass concentration comparable to a synthetic medium. All three strains significantly reduced the concentration of NO3 and PO4 (95 and 85%, respectively), with no difference between Na2CO3 or NaHCO3. Finally, Chlorella sp. obtained the highest removal efficiency of the pesticide (Chlorpyrifos), followed by Scenedesmus and Hapalosyphon sp. (100, 75, and 50%, respectively). This work shows that it is possible to use this type of waste as an alternative source of nutrients to obtain biomass and metabolites of interest, such as lipids and carbohydrates, to produce biofuels.
FORMATION OF URBAN ENVIRONMENT AND CITY BRAND BASED ON CITIZEN OPINIONS
Authors: Gorgorova Yu.
Published: February 2022

The development and functioning of the city brand depends on the support and approval of citizens at different levels. For example, participation in the formation of the urban environment of activists, attraction of the creative class or understanding of the processes in the city, its ordinary residents. Experience shows when the opinion of citizens is taken into account when forming a city brand, the residents are more attentive to the created environment, identify themselves with the city and feel a sense of pride in their city. Ignoring the opinion of citizens leads to protest art, vandalism, discontent and irritation of people. The author lists the questions to ask citizens during the survey and explains how the answers to these questions can influence the formation of the urban environment, built on the city's brand
Sarcoma de Ewing en Pelvis Pediátrica
Authors: Jiménez Soto Daniela
Published: February 2022

El sarcoma de Ewing en pelvis pediátrica se vuelve todo un enigma, en relación a su manejo interdiciplinar. Es uno de los tumores más complejos de tratar y con un pronóstico reservado en muchos de los casos.

Son poco frecuentes, pero cuando se presenta existen pocas estrategias en pacientes pediátricos, en cuanto su manejo, en esta revisión se recopilan los datos más importantes para el diagnóstico, tratamiento y evolución en todos los casos.
Principios básicos del abordaje del dolor.
Authors: Solano Guillén María Jesús , Villalobos Zúñiga Gerardo
Published: February 2022

La Asociación Internacional para el Estudio del Dolor, define el dolor como una experiencia sensorial y emocional desagradable, asociada a un daño tisular real o potencial. A nivel mundial es considerado un problema de salud pública importante, siendo una de las principales causas de atención médica en los centros de salud tanto públicos como privados. Además repercute directamente sobre la calidad de vida de la persona que lo padece, principalmente en los ámbitos laboral, social y económico. El dolor desempeña una función biológica actuando como mecanismo de defensa del organismo. Se estima que aproximadamente un 60% de la población ha presentado dolor al menos una vez en su vida. El dolor puede categorizarse según distintos criterios de acuerdo a las características que presente dentro de las que destacan; el tiempo de duración clasificándolo en agudo o crónico, fisiopatológicamente en nociceptivo o neuropático y por localización en somático o visceral. El proceso neuronal del dolor tiene una alta complejidad y va a depender según cada individuo. Además es fundamental la participación de nocireceptores, que son los receptores encargados de transmitir el estímulo doloroso hasta la médula espinal, posteriormente al tálamo y finalmente al sistema nervioso central, específicamente a la corteza somatosensorial. Existen cuatro fenómenos que participan en el proceso nociceptivo los cuales son: transducción, transmisión, modulación y percepción. Para el manejo del dolor existen diferentes opciones terapéuticas que se pueden dividir en farmacológicas y no farmacológicas. La estrategia no farmacológica de mayor relevancia es la fisioterapia, mientras que las medidas farmacológicas están basadas en la escala analgésica de la OMS.
Obesidad: Mecanismos, fisiopatología y tratamiento integral
Authors: Martinez Sanchez Lina MarÍa , Pérez Sara
Published: February 2022

En el siglo 21, la obesidad constituye un problema de salud pública al presentarse como una enfermedad metabólica adversa y prevalente, que al encontrarse en un ambiente toxico; en el que la comida es barata, sabrosa, ultra procesada y abundante; aumenta a un ritmo acelerado. Aproximadamente el 17% de los niños estadounidenses y 35% de los adultos son obesos y los gastos anuales atribuidos a la obesidad y cuidados relacionados superan los 190.000 millones de dólares, constituyendo así un problema para los sistemas de salud y los recursos destinados a estos, es por esto que la promoción y la prevención cobran importancia, al igual que los tratamientos integrales, en los que se tienen en cuenta todas las esferas del individuo y la naturaleza multifactorial de esta enfermedad, es por esto que el objetivo de la presente revisión es plantear una revisión de los mecanismos, fisiopatología y tratamientos que existen actualmente para el manejo integral de la obesidad, con la finalidad de establecer sus ventajas, desventajas y resaltar su importancia. Para la realización de este se realizó una búsqueda bibliográfica en bases de datos como WoS, Education-Research, Lilacs y Redalyc, mediante la selección de palabras clave como “obesidad”, “sobrepeso” “fisiopatología” “tratamiento”. Tras la identificación de los artículos de interés, se llevo a cabo una lectura critica para seleccionar los que mejor se correlacionaran con el objetivo de la revisión, delimitando así una muestra final.
Perancangan Media Promosi Batik Mimi di Kota Solok dalam Bentuk Audio Visual
Authors: Oktavianus Afif , Iskandar Riki , Afdhal Vernanda Em
Published: February 2022

Perancangan Video Promosi Batik Mimi dilatar belakangi oleh kurangnya pengetahuan masyarakat tentang Batik Mimi. Perancang membutuhkan data-data yang akan membantunya dalam proses mendesain, dimana dilakukan melalui observasi, wawancara, dan studi pustaka. Dari data, dilakukan analisis dengan menggunakan metode analisis data yaitu teori analisis S.W.O.T membahas mengenai Video Promosi dan melihat dari sisi kelemahan yang menjadi motivasi untuk meningkatkan pesan dalam Video Promosi, dan melihat respon dari masyarakat tentang Batik Mimi di Kota Solok.Proses perancangan menghasilkan media utama berupa Video Promosi yang berdurasi 00.02.29 detik yang menampilkan tayangan macam macam batik mimi di Kota Solok, Video Promosi Batik Mimi sebagai media promosi dilengkapi media pendukung seperti Poster, X-Banner, paperbag, Pin, Baju.
CONDICIONANTES DE PRESERVAÇÃO AMBIENTAL : ESTUDO DE CASO DO MUNICÍPIO DE EQUADOR /RN
Authors: Isabel Lausanne Fontgalland Isabel , Sabino de Oliveira Zenon
Published: February 2022

The present work refers to a case study related to the environmental impacts caused by mining and prospecting activities, aiming to describe the transformation impacts of the typical landscape of the Caatinga do Seridó Potiguar Biome, in the municipality of Ecuador, state of Rio Grande From north. In this study, the impact on local biodiversity due to mining and kaolin extraction was studied. The scenic beauty is our focus of study as well as studying ways of mitigation to restore the natural state of the Seridó landscape. As discussions and results, Payment for Environmental Services (PES) is presented as an appropriate form, given the advance in the regulatory frameworks of payment for environmental services projects, as well as the dissemination of knowledge about this instrument.
Avaliação de Solturas em Artroplastias com Dor Crônica
Authors: Gustavo Mota Rios  , Rogério Meira Barros  , Robson Rocha da Silva  , Flávio Robert Santana  , Marcos Almeida Matos
Published: February 2022

O objetivo deste artigo é apresentar um algoritmo de investigação de soltura séptica ou asséptica em pacientes com dor crônica em artroplastias, focando nos princípios e guias de conduta mais atualizados da literatura ortopédica. A investigação de soltura em artroplastia deve ser baseada na avaliação clínica, mas deve incluir outros aspectos igualmente importantes. Características tais como presença de fístula, culturas positivas, VHS maior que 30mm, PCR maior que 10mg/L, e leucocitose com neutrofilia nos líquidos ou secreções de punção devem ser considerados para o diagnóstico de soltura séptica. Radiografia simples, cintilografia, tomografia e ressonância magnética são úteis para avaliação de solturas. Ressonância magnética oferece melhor capacidade de diferenciaçãoentre soltura séptica ou asséptica, especialmente quando utilizada a tecnologia MAVRIC (Multiacquisition with variable resonance image combination) que tem maior capacidade de supressão de artefatos metálicos. Nestes casos, por exemplo, são melhor definidas zonas de osteólise para casos assépticos ou de sinovite lamelada para casos de infecção.
Câncer da Vesícula Biliar - Relato de Casos
Authors: Marcos Dantas Moraes Freire  , Luis Fernando Pinto Johnson  , Mateus Dantas Moraes Freire  , Maria Luiza Silva Casé  , Lucas Torres Pires  , André Luis de Godoy  , André Ney Menezes Freire
Published: February 2022

O câncer da vesícula biliar é uma doença que representa um grande desafio para médicos clínicos e cirurgiões, por possuir características especiais: alta capacidade de disseminação, invasão por contiguidade e continuidade, crescimento rápido e agressivo, além de apresentação clínica insidiosa, geralmente apresentando sintomas quando o quadro já está avançado. Apresentamos dois casos com desfechos completamente diferentes: um do Hospital Santa Izabel e outro do hospital especializado em câncer A.C. Camargo de São Paulo. Discutimos ainda o tratamento atual e as possíveis intervenções que podem ser traçadas no futuro para o aprimoramento no diagnóstico e na terapêutica dessa grave doença.
Esquistossomose Pseudotumoral Mimetizando Recidiva de Câncer de Pênis: Um Relato de Caso e Revisão de Literatura
Authors: Luiz Eduardo Café Cardoso Pinto  , Benedita Débora Aguiar  , Bruno Suffredini Figueiredo  , Jailton Campos Araújo  , Marclei Pereira de Oliveira  , Merson Silva de Almeida  , Thiago Aragão Silva Trabuco
Published: February 2022

A esquistossomose é uma doença parasitária crônica, considerada um problema de saúde pública mundial, principalmente nos países em desenvolvimento, situados em áreas tropicais e subtropicais. O carcinoma de pênis é um cancer agressivo, caracterizado por ser invasivo e de disseminação metastática precoce, ocorrendo principalmente nos países em desenvolvimento, como o Brasil. Relato de caso de paciente de 48 anos com diagnóstico de carcinoma espinocelular de pênis, estágio clínico IIIA, submetido a penectomia parcial. No seguimento, foi submetido a linfadenectomia retroperitoneal e pélvica, tendo como resultado linfonodos pélvicos comprometidos, sendo encaminhado para quimioterapia adjuvante. Durante seguimento, PET-TC evidenciou linfonodomegalias discretamente hipermetabólicas em cadeias retroperitoneais de asspecto suspeito para acometimento neoplásico. A nova linfadenectomia retroperitoneal resultou em anatomopatológico de linfadenite granulomatosa associada a ovos de Schistossoma mansoni. A associação de câncer de pênis e esquistossomose é rara. Ambas são doenças que afetam mais preponderantemente países em desenvolvimento. O caso relatado demonstra a necessidade de se considerar a esquistossomose no diagnóstico diferencial de tumorações linfonodais ao exame de imagem, uma vez que o Brasil está entre os países de maior prevalência da doença.
Description of Dental and Oral Health Maintenance Behavior of Elementary School Students
Authors: Katili Laurencia , Anindita Pritartha S. , Juliatri Juliatri
Published: February 2022

Abstract: The 2018 Basic Health Research (Riskesdas) stated that the prevalence of students with dental and oral problems in North Sulawesi showed a fairly high number, which was 66.5%. In children, behavioral factors that ignore dental and oral hygiene could affect the development of dental and oral health. Behavior can be measured by  using three domains, namely knowledge, attitudes, and actions. This study aimed to obtain the description of dental and oral health maintenance behavior of elementary school students. This was a descriptive study with a cross sectional design. Population of this study were students at the elementary school SDN 1 Bulawan East Bolaang Mongondow, North Sulawesi, Indonesia. Meanwhile, samples were students of grades 5-6 totaling 44 children obtained by using total sampling method. Data were collected by using an online oral health maintenance behavior questionnaire via googleform. The results showed that the measurement scores were as follows: category of knowledge was 405; category of attitude was 394, category of action was 396, with a total score of 1195. In conclusion, the behavior of dental and oral health maintenance of students at SDN 1 Bulawan is classified as good.Keywords: behavior; dental and oral health maintenance Abstrak: Riset Kesehatan Dasar (Riskesdas) 2018 menyebutkan bahwa prevalensi siswa yang bermasalah gigi dan mulut di Sulawesi Utara menunjukkan angka yang cukup tinggi yaitu sebesar 66,5%. Pada anak faktor perilaku mengabaikan kebersihan gigi dan mulut berpengaruh terhadap perkembangan kesehatan gigi dan mulut. Perilaku dapat diukur dengan tiga domain yaitu pengetahuan, sikap, dan tindakan. Penelitian ini bertujuan untuk mendapatkan gambaran perilaku pemeliharaan kesehatan gigi dan mulut siswa sekolah dasar. Jenis penelitian ialah deskriptif dengan desain potong lintang. Populasi penelitian ini yaitu siswa di SDN 1 Bulawan, Bolaang Mongondow Timur, Sulawesi Utara. Sampel penelitian yaitu anak SDN kelas 5-6 berjumlah 44 orang. Teknik pengambilan sampel yang digunakan metode total sampling. Pengumpulan data menggunakan kuesioner perilaku pemeliharaan kesehatan gigi dan mulut secara online melalui googleform. Hasil penelitian mendapatkan bahwa skor hasil pengukuran kategori pengetahuan sebesar 405, kategori sikap 394, kategori tindakan 396, dengan skor total 1195. Simpulan penelitian ini ialah gambaran perilaku pemeliharaan kesehatan gigi dan mulut siswa SDN 1 Bulawan tergolong baik.Kata kunci: perilaku; pemeliharaan kesehatan gigi dan mulut
HUBUNGAN SELF CARE DENGAN KOMPLIKASI DIABETES MELITUS PADA PASIEN DENGAN DIABETES MELITUS TIPE 2 DI KLINIK HUSADA SARIO MANADO
Authors: Sasombo Antania , Katuuk Mario Esau , Bidjuni Hendro
Published: February 2022

AbstractBackground: diabetes mellitus is a metabolic disease characterized by hypoglycemia.Diabetes effects can result in the body's organs if the condition is not managed or controlledproperly. For this reason, it is necessary to do DM self-care which is an independent actionthat must be taken by DM Sufferers in their daily lives to control Blood Glucose. Aim: Thisstudy was aimed to determine corelation between the self-care whit the complications ofpatients with type 2 diabetes mellitus at the Husada Sario Manado Clinic. Methods:Thisresearch is a corrosive cross-sectional study, it’s done to 72 patients with type 2 DiabetesMelitus with research tools from questionnaire and analysis using chi-square. Results: Thisresearch is picking up p-value results. Conclusion: Most of the Diabetes Melitus type 2 at heHusada Sario Manado Clinic has a good self care, with most of the patients havinghypertensive complications. There’s no link between self care and the complications ofDiabetes Melitus on patients with type 2 Diabetes Melitus.Keywords: Diabetes Mellitus type 2, complications of Diabetes Mellitus, Self Care.AbstrakLatar belakang: Diabetes Melitus merupakan penyakit metabolik dengan karakteristikhipeglikemia. Jika diabetes tidak segera dikendalikan atau dikendalikan dengan baik dapatmengakibatkan komplikasi diabetes yang dapat terjadi pada organ-organ tubuh. Untuk itu perludilakukannya Self care DM yang merupakan tindakan mandiri yang harus dilakukan olehpenderita DM dalam kehidupanya sehari-hari untuk mengontrol glukosa darah.Tujuanpenelitian untuk menganalisis hubungan self care dengan komplikasi Diabetes Melitus tipe 2di Klinik Husada Sario Manado. Metode Penelitian ini adalah penelitian cross-sectional yangbersifat deskriptif korelatif, yang dilakukan kepada 72 pasien Diabetes Melitus tipe 2 denganInstrument penelitian yang digunakan yaitu kuesioner dan dianalisis menggunakan Chi Square.Hasil Penelitian di dapati hasil p-value (0,802) > α = (0,05) . Simpulan Sebagian besar pasienDiabetes Melitus tipe 2 di Klinik Husada Sario Manado memiliki self care baik, dengansebagian besar pasien memiliki komplikasi hipertensi. Tidak ada hubungan yang signifikanantara Self Care dengan komplikasi Diabetes Melitus pada pasien dengan Diabetes Melitus tipe2.Kata Kunci : Diabetes Melitus tipe 2, komplikasi Diabetes Melitus, Self Care.
HUBUNGAN DUKUNGAN SOSIAL DAN TINGKAT KECEMASAN PADA KELOMPOK PEKERJA PNS YANG MENGHADAPI MASA PENSIUN DI POIGAR MINAHASA SELATAN
Authors: Ratu Esterlani Waliani , Rompas Sefti , Simak Valen
Published: February 2022

AbstractBackground of this research is Retirement is a time full of challenges because there are changessuch as from actively working to not working, from having a position to staying at home, fromgetting a high income to a lower income. Civil servants experience anxiety when facingretirement. This happens because there is no social support. Aim of this study was to determinethe relationship between social support and anxiety levels in the group of civil servants facingretirement in Poigar Minahasa Selatan. The research method used descriptive research withsamples, in this study there were 50 respondents obtained through total sampling. And using aquestionnaire research instrument and tested using Chi-square. The results of this study showedthat high social support had low anxiety as many as 25 people (100.0%). And low social supporthas high anxiety as many as 25 people (100.0%). The results of the analysis obtained value =0.000 <0.05. High Social Support has Low Anxiety as many as 25 people (100.0%). And lowsocial support has high anxiety as many as 25 people (100.0%). The results of the analysis socialsupport and anxiety levels in the group of civil servants facing retirement in Poigar MinahasaSelatan obtained value = 0.000 <0.05. Conclusion High social support has low anxiety whilelow social support has high anxiety. And there is relationship between social support and anxietylevels in the group of civil servants facing retirement.Keywords: Work; Social Support; Anxiety; RetirementAbstrakLatar Belakang Pensiun merupakan masa yang penuh tantangan karena terjadi perubahanseperti dari aktif bekerja menjadi tidak bekerja, dari memiliki jabatan menjadi diam di rumah,dari mendapat penghasilan tinggi menjadi penghasilan yang lebih rendah. Pegawai negeri sipilmengalami kecemasan ketika menghadapi masa pensiun. Hal ini terjadi karena tidak adadukungan sosial. Tujuan penelitian ini adalah untuk mengetahui hubungan dukungan sosial dantingkat kecemasan pada kelompok pekerja PNS yang menghadapi masa pension di poigarminahasa selatan. Metode penelitian menggunakan penelitian deskriptif dengan Sampel, padapenelitian ini berjumlah 50 responden yang diperoleh melalui total sampling. Dan menggunakaninstrumen penelitian Kuesioner dan di uji menggunakan Chi-square. Hasil penelitian didapatkanDukungan Sosial yang tinggi memiliki Kecemasan Rendah sebanyak 25 orang (50,0%). DanDukungan sosial rendah memiliki Kecemasan yang tinggi sebanyak 25 orang (50,0%). Hasilanalisa dukungan sosial dan tingkat kecemasan pada kelompok pekerja PNS yang menghadapimasa pension di poigar minahasa selatan diperoleh ρ value = 0,000 < 0,05. KesimpulanDukungan Sosial yang tinggi memiliki Kecemasan Rendah sedangkan dukungan sosial rendahmemiliki kecemasan yang tinggi. Dan terdapat hubungan dukungan sosial dan tingkat kecemasanpada kelompok pekerja PNS yang menghadapi masa pensiun.Kata Kunci : Bekerja; Dukungan Sosial; Kecemasan; Pensiun
ANALISIS PENGELOLAAN DANA DESA DALAM PELAKSANAAN PEMBANGUNAN TAHUN ANGGARAN 2020 (STUDI PADA DESA WAMBOULE KABUPATEN BUTON UTARA)
Authors: BB Suriyani , Liwaul Liwaul , Listafila Gita
Published: February 2022

This study aims to describe the management of village funds in the village of Wamboule, North Buton Regency and to describe the implementation of the development of the village of Wamboule, North Buton Regency. The data analysis method used in this research is descriptive qualitative. This study uses data sourced from primary and secondary data. The results of this study state that the management of village funds in Wamboule village, North Buton Regency can be said to be good based on three indicators, namely planning, implementation and accountability in accordance with the mandate of Government Regulation of the Republic of Indonesia Number 8 of 2016 concerning the second Amendment to Government Regulation of the Republic of Indonesia Number 60 of 2014 concerning Village Funds sourced from the State Budget and Expenditure Revenue. The implementation of the development of the Wamboule village, North Buton Regency in 2020 is going well based on the aspect of development and the use of the budget in accordance with the plan. In the implementation of development, the Wamboule village government always involves the community in both physical and non-physical development.
PENINGKATAN HASIL BELAJAR MENGGIRING BOLA DENGAN METODE INQUIRY
Authors: Yusril Muh.
Published: February 2022

This research aims to find out whether students' learning outcomes of Dribbling Learning In Football Games can be improved by using inquiry method. Instruments used in this research namely dribbling work tests on football games and motivational observation, cooperation and development of football movements.This research is Class Action Research (CAR). As for the subjects in this study are grade VIII 8students that consists of 28 students consisting of 13women and 15 men.The results of the study can be concluded that efforts to improve the results of dribbling learning in football games with inkuiry methods in grade VIII students of SMP Negeri 8 Palopo are characterized by an increase in the average grade of students. The average grade of students in pre-tinence activities was 70.67 with a completion percentage of 42.86%. The condition increased the average grade of students in cycle I by 73.74 and the completion percentage by 60.71%. However, the increase has not yet reached the previously set target. Then after moving on to cycle II the average grade of student football increased again by 80.82 with a completion percentage of 85.71%. This indicates that the previously set target has been reached so that research is stopped in cycle II. The dribbling ability in the game of learner football is increased by being marked by all students completed KKM (Minimum Completion Criteria) which is 75.
Identifikasi Jamur Rhizosfer di Lahan Tanaman Bawang Merah (Allium ascalonicum L.) Bergulma di Desa Bendang Raya Kecamatan Tenggarong
Authors: Akhsan Nik'matuljannah , Sila Surya , Syaifuddin Encik Akhmad , Kurniati Ira
Published: February 2022

Penelitian bertujuan untuk mengetahui jenis jenis jamur rizosfer pada tanaman bawang merah di Desa Bendang Raya Kecamatan Tenggarong. Penelitian ini dilaksanakan pada bulan November 2019 sampai Januari 2020 di Laboratorium Hama Penyakit Tumbuhan Fakultas Pertanian Universitas Mulawarman. Pengambilan sampel tanah rizosfer dilakukan pada lahan yang bergulma terus (tanpa pengendalian gulma), bergulma empat minggu, bergulma tiga minggu, bergulma dua minggu dan bergulma satu minggu. Pengambilan sampel pada kedalaman 0-20 cm. Diambil 12 titik sampel, dikomposit, lalu diambil 1 kg untuk dianalisis di laboratorium. Hasil penelitian ini menunjukkan bahwa kepadatan populasi jamur pada lahan bergulma terus (tanpa pengendalian gulma) adalah 34x103 terdiri dari 4 jenis Jamur yaitu; Penicillium sp.1, Rhizoctonia sp., Gonytrichum sp., Aspergillus sp. pada lahan bergulma empat minggu terdapat 30x103 terdiri dari 3 jenis jamur yaitu Aspergillus sp., Botrytis sp. dan Aureobasidium sp., pada lahan bergulma tiga minggu terdapat 24x103 terdiri dari 3 jenis jamur yaitu Pythium sp., Fusarium sp., dan Aspergillus sp., pada lahan bergulma dua minggu terdapat 23x103 terdiri dari 2 jenis jamur yaitu: Pennicillium sp., Trichoderma sp. dan pada lahan bergulma satu minggu terdapat 10x103 yang terdiri dari 2 jenis Jamur yaitu Trichoderma sp. dan Aspergillus sp.