bluuebunny/crossref_metadata_2025 huggingface dataset:
Functional Anterior Temporal Lobectomy for Temporal Lobe Epilepsy: A Novel, Alternative, and Less Invasive Therapy
Authors: Liu Yong , Ren Yutao , Meng Qiang , Wu Hao , Dong Shan , Li Huanfa , Liu Xiaofang , Li Kuo , Du Changwang , Zhang Hua
Published: November 2022

BACKGROUND:

Anterior temporal lobectomy is the most effective treatment for intractable temporal lobe epilepsy (TLE). However, patients are reluctant to choose this surgery for fear of risks after large frontotemporal craniotomy, and epileptologists likewise have a cautious attitude because of surgical trauma. Functional anterior temporal lobectomy (FATL) is a minimally invasive surgery procedure for addressing the above concerns.

OBJECTIVE:

To report preliminary data on this procedure and its safety and efficacy for treating TLE.

METHODS:

This consecutive case series study was conducted between October 2020 and September 2021. Patients with TLE underwent FATL by minicraniotomy with a diameter of 3 cm. Surgery duration, postoperative complications, and seizure control are described herein. Seizure outcomes were classified using Engel classifications.

RESULTS:

A total of 25 patients undergoing FATL for TLE were enrolled. The median epilepsy duration was 8 years. The median surgery duration was 165 min. The median blood loss was 100 mL. The median postoperative hospital stay was 8 days. No deaths occurred after surgery. Only 1 patient presented with a cerebrospinal fluid disorder that was successfully treated using a ventriculoperitoneal shunt. At the last follow-up, 23 patients (92%) were seizure-free (Engel-Ia), 1 patient remained substantially improved (Engel-II), and 1 patient obtained worthwhile seizure reduction (Engel-III).

CONCLUSION:

Our pilot study suggests that FATL is a viable surgical therapy for TLE. This method has the advantages of minimal invasiveness and high seizure-free rate. A controlled trial is warranted to verify the efficacy and safety of FATL comparing with anterior temporal lobectomy.
Targeting Drosophila Sas6 to mitochondria reveals its high affinity for Gorab
Authors: Kovacs Levente , Fatalska Agnieszka , Glover David M.
Published: November 2022

The ability to relocalize proteins to defined subcellular locations presents a powerful tool to examine protein-protein interactions that can overcome a tendency of non-targeted exogenous proteins to form inaccessible aggregates. Here, we show that a 24-amino-acid sequence from the Drosophila proapoptotic protein Hid's tail anchor (HTA) domain can target exogenous proteins to the mitochondria in Drosophila cells. We use this HTA tag to target the Drosophila centriole cartwheel protein Sas6 to the mitochondria, and show that both exogenous and endogenous Gorab can be co-recruited from the Golgi to the new mitochondrial site. This accords with our previous observation that monomeric Drosophila Gorab binds Sas6 to become centriole associated with a 50-fold greater affinity than dimeric Gorab binds Rab6 to become localized at the Golgi. Strikingly, Drosophila Sas6 can bind both Drosophila Gorab and its human GORAB ortholog, whereas human SAS6 is unable to bind either GORAB or Gorab. We discuss these findings in relation to the evolutionary conservation of Gorab and the divergence of Sas6, possibly reflecting known differences in persistence of the cartwheel in the centriole duplication cycle of fly and human cells.
Early detection of external cervical resorption in posterior teeth: a radiographic, cross-sectional study of an adolescent population
Authors: Suhr Villefrance Julie , Wenzel Ann , Kirkevang Lise-Lotte , Væth Michael , Christensen Jennifer , Matzen Louise Hauge
Published: November 2022

Objectives:

To establish the prevalence and severity of external cervical resorption (ECR) in posterior teeth observed in bitewing (BW) radiographs in an epidemiological study of a 17-year-old patient population from community dentistry. Furthermore, to assess the potential predisposing factors for ECR.

Methods:

Posterior BWs from 5596 patients (2717 females, 2879 males; mean age 17.8 years) were assessed by three observers in order to detect ECR (using Heithersay’s classification system, severity classes 1–4). When ECR was suspected, cone beam CT (CBCT) was offered to verify diagnosis. Prevalence was estimated based on ECR suspected in BWs and finally in CBCT. Possible predisposing factors (orthodontic treatment, trauma, and periodontal disease) were recorded and assessed for association with ECR.

Results:

In 41 patients, ECR was suspected in BWs (suspected prevalence 0.73%). 32 patients accepted CBCT examination, of which eight were verified to have ECR (final prevalence 0.18%). In 24 patients, other disease entities and abnormal tooth morphology, that had mimicked ECR in BWs, excluded ECR in CBCT. ECR severity ranged from class 1–3 in BW and 2–4 in CBCT. All but one case had not been diagnosed by the patient’s community dentist. No statistically significant association between predisposing factors and ECR was identified.

Conclusions:

ECR had low prevalence in this adolescent population, as observed in both BWs and CBCT. Still, early detection of ECR is important for treatment prognosis, and attention should be paid to this disease entity when assessing BWs obtained for other diagnostic purposes. CBCT may subsequently aid in verifying the disease.
Οφθαλμολογικές διαταραχές σε ασθενείς με πολλαπλή σκλήρυνση
Authors: Μητώνα Ελένη
Published: November 2022

Η πολλαπλή σκλήρυνση είναι μια χρόνια νόσος του κεντρικού νευρικού συστήματος (ΚΝΣ), άγνωστης αιτιολογίας, στην οποία συμβαίνει απώλεια νευρολογικών λειτουργιών λόγω αυτοάνοσης απομυελίνωσης. Παρουσιάζει αρκετές κλινικές εκδηλώσεις που σχετίζονται με βλάβες του εγκεφαλικού στελέχους, όπως διαταραχές των κινητικών και αισθητηριακών λειτουργιών, γνωστικές, οπτικές ,ουρογεννητικές και ψυχικές διαταραχές. Οι περίοδοι ύφεσης και επιδείνωσης μπορεί να εναλλάσσονται.Σκοπός της παρούσας διατριβής ήταν η διερεύνηση των οφθαλμολογικών διαταραχών ασθενών με πολλαπλή σκλήρυνση, μέσα από μια ανασκόπηση μελετών αλλά και στατιστική ανάλυση δεδομένων ασθενών του πανεπιστημιακού νοσοκομείου Ιωαννίνων. Από την ποσοτική έρευνα βρέθηκε πως από 149 ασθενείς με πολλαπλή σκλήρυνση, οι 42( 28,2% ) είχαν διπλωπία και εξ αυτών οι 17 την εμφάνισαν από την έναρξη της νόσου .Επίσης 24 ασθενείς (16,1%) είχαν οπτική νευρίτιδα και εξ αυτών οι 12 την εμφάνισαν στη έναρξη της νόσου. Στην κλίμακα Expanded Disability Status Scale το 89, 9% είχε σκορ έως και 4,που δείχνει νευρολογικές δυσλειτουργίες, το 5, 4% είχε σκορ 4-6 που δείχνει σημαντικές δυσλειτουργίες στη βάδιση και το υπόλοιπο 4,7% είχε σκορ πάνω από 6, που δείχνει αναπηρίες λόγω της σκλήρυνσης. Τέλος, από τα αποτελέσματα στην Οπτική Τομογραφία η οποία πραγματοποιήθηκε σε λίγα περιστατικά, φάνηκε πως 2 ασθενείς είχαν ΑΡ.97μm/ΔΕ 99μm, άλλοι δύο είχαν λέπτυνση στοιβάδας και ένας ασθενής είχε αύξηση πάχους νευροαρτηριακής στοιβάδας ΔΕ, ΑΡ κ.φ, άλλος ένα είχε φυσιολογικά τα του κεντρικού βοθρίου αλλά παρουσιάζεται προχωρημένη ατροφική αλλοίωση του οπτικού νεύρου ΔΟ λόγω της MS χωρίς παθολογικά ευρήματα εκ της ωχράς και ακόμα ένας είχε λέπτυνση ΔΕ οφθαλμού πάχους ινών, ενώ σε έναν ακόμα ζητήθηκε OCT. Στο υπόλοιπο 94, 6% δεν πραγματοποιήθηκε OCT. Η μετανάλυση εξέτασε τις παραμέτρους OCT σε ασθενείς με πολλαπλή σκλήρυνση και υγιή άτομα. Η εκτιμώμενη απώλεια RNFL σε ασθενείς με πολλαπλή σκλήρυνση χωρίς οπτική νευρίτιδα σε σύγκριση με τους μάρτυρες ήταν χαμηλότερη από αυτή που ακολούθησε MSON. Μεγαλύτερη λέπτυνση του αμφιβληστροειδούς παρατηρήθηκε στα μάτια ασθενών με προηγούμενο ιστορικό ΟΝ από ό,τι σε αυτά των μαρτύρων. Επιπλέον, οι μετρήσεις οπτικής οξύτητας βρέθηκαν να είναι σε μεγάλο βαθμό ανάλογες με τις τιμές πάχους RNFL. Συμπεραίνεται, λοιπόν, πως οι μετρήσεις του πάχους της RNFL και του όγκου της ωχράς κηλίδας (MV) ενδέχεται να είναι σε θέση να αποκαλύψουν πληροφορίες σχετικά με την απώλεια νευρα-αξόνων της οπτικής οδού και την αραίωση των νευρωνικών κυττάρων, ανεξάρτητα από το ιστορικό ΟΝ. Η λέπτυνση της RNFL θα μπορούσε να χρησιμοποιηθεί ως πιθανός δείκτης έκβασης της νόσου. Επιπλέον, το RNFL μπορεί να παρέχει συμπληρωματικές πληροφορίες σε σχέση με την όραση των ασθενών με πολλαπλή σκλήρυνση.Λέξεις-κλειδιά: Σκλήρυνση κατά πλάκας, Τομογραφία Οπτικής Συνοχής, Απώλεια RNFL
Συγκρότηση ενός μοντέλου σχεδιασμού και διαχείρισης αποτελεσματικών ανταμοιβών με στόχο τη βελτίωση της απόδοσης του ανθρώπινου δυναμικού των ελληνικών ξενοδοχειακών επιχειρήσεων
Authors: Πνευματικούδη Κυριακή
Published: November 2022

Η διδακτορική διατριβή ασχολείται με τη διαχείριση ανταμοιβών και τη σχέση τους με την απόδοση του ανθρώπινου δυναμικού στις ξενοδοχειακές επιχειρήσεις. Ειδικότερα, ταξινομεί και παρουσιάζει τη διεθνή επιστημονική αρθρογραφία και έρευνα για τις ανταμοιβές ανθρώπινου δυναμικού και τους δείκτες μέτρησης της ξενοδοχειακής απόδοσης. Συγκροτεί ένα ολοκληρωμένο μοντέλο διαχείρισης αποτελεσματικών ανταμοιβών για τη βελτίωση της απόδοσης του ανθρώπινου δυναμικού στα ξενοδοχεία, λαμβάνοντας υπόψη πληθώρα δημογραφικών και εργασιακών χαρακτηριστικών. Τέλος, η διατριβή παρουσιάζει τα αποτελέσματα εμπειρικής έρευνας σχετικά με τον τρόπο με τον οποίο ανταμείβεται το ανθρώπινο δυναμικό και την επίδραση των ανταμοιβών στην απόδοση του ανθρώπινου δυναμικού στα ελληνικά ξενοδοχεία υψηλών κατηγοριών. Σύμφωνα με τα αποτελέσματα της έρευνας πέρα από την παροχή ενδιαφέροντος αντικειμένου εργασίας, δεν υπάρχουν άλλες ανταμοιβές που να επιδρούν στην απόδοση στο σύνολο των εργαζομένων, αλλά συγκεκριμένες πρακτικές ανταμοιβής επηρεάζουν την απόδοση σε συγκεκριμένες περιπτώσεις δημογραφικών και εργασιακών χαρακτηριστικών του ανθρώπινου δυναμικού των ξενοδοχείων.
Burden of disease in Colombian Orinoquia, 2017
Authors: Gutiérrez-Lesmes Oscar , Grisales-Romero Hugo
Published: November 2022

Background:Population health diagnoses are a fundamental tool to guide health policies and programs, and consequently, public health requirements. In this perspective, the burden of disease in inhabitants of Colombian Orinoquia is quantified for the first time.

Methods:A descriptive population-based study that was based on secondary sources was carried out, which aimed at measuring the burden of the disease in the Colombian region of Orinoquia, using the simplified synthetic indicator of disability-adjusted life years (DALYs) of the global health estimation methodology. We used mortality records from the National Administrative Department of Statistics (DANE) and service provision records from the Ministry of Health and Social Protection of Colombia, both records from the year 2017, available on the Integrated Social Protection Information System.

Results:288,740.2 DALYs occurred (95% UI 210,714.6-382,948.8), with higher reports for men (59%); group of non-communicable diseases accounted for 62.3% of DALY (179,993.6, 95% UI, 115,030.2-268,405.0), followed by external cause injuries group which contributed 24.6% (71,000.0, 95% UI, 25,638.1-134,013.1), and group of communicable, maternal, neonatal, and nutritional disorders which contributed 13.1% (37,746.0, 95% UI, 28,048.0-50,239.7). Interpersonal violence was the primary cause specific of DALYs with 9.8% of the burden, (28,290.0, 95% UI, 7,365.1-64,208.1).

Conclusions:Most DALYs in Orinoquia are produced by non-communicable diseases (NCD), largely caused by neoplasms and cardiovascular disease, which increased with age. However, when considered by specific cause of illness or injury, interpersonal violence is indicated as the main cause of DALYs, affecting mainly young men, possibly as an expression of social inequality, substance use, criminality, and insecurity. It is important to highlight that this region has been recognized as an area of armed conflict, drug trafficking, and poverty.
Machine learning algorithms: their applications in plant omics and agronomic traits’ improvement
Authors: Isewon Itunuoluwa , Apata Oluwabukola , Oluwamuyiwa Fesobi , Aromolaran Olufemi , Oyelade Jelili
Published: November 2022

Agronomic traits of plants especially those of economic or aesthetic importance are threatened by climatic and environmental factors such as climate change, biotic, and abiotic stresses. These threats are now being mitigated through the analyses of omics data like genomics, transcriptomics, proteomics, metabolomics, and phenomics. The emergence of high-throughput omics technology has led to an avalanche of plant omics data. Plant research demands novel analytical paradigms to extract and harness large plant omics data for plant improvement effectively and efficiently. Machine learning algorithms are well-suited analytical and computational approaches for the integrative analysis of large unstructured, heterogeneous datasets. This study presents an overview of omics approaches to improve plant agronomic traits and crucial curated plant genomic data sources. Furthermore, we summarize machine learning algorithms and software tools/programming packages used in plant omics research. Lastly, we discuss advancements in machine learning algorithms' applications in improving agronomic traits of economically important plants. Extensive application of machine learning would advance plant omics studies. These advancements would consequently help agricultural scientists improve economically important plants’ quality, yield, and tolerance against abiotic and biotic stresses and other plant health-threatening issues.
Cookies rich in iron (Fe), folic acid, cobalamin (vitamin B12), and antioxidants: a novel functional food potential for adolescent with anemia
Authors: Bolang Alexander Sam Leonard , Rizal Mochammad , Nurkolis Fahrul , Mayulu Nelly , Taslim Nurpudji Astuti , Radu Son , Samtiya Mrinal , Assa Youla Annatje , Herlambang Hendra Agung , Pondagitan Alpinia Shinta , Vivo Christopherous Diva
Published: November 2022

Background: Anemia is a global public health problem, including Indonesia with 32% of adolescents are anemic. This study aims to process porang flour, moringa leaves, and tempe into cookies that are high in iron (Fe), folic acid, cobalamin (vitamin B12), and antioxidants as potential functional food snacks for adolescents with anemia.

Methods: This study is experimental with a completely randomized trial design (CRD) with three treatments and replications. There are three comparison formulations of a combination of porang, moringa leaves, and black soybean-based tempe; respectively F1 (91:3:3:3)%, F2 (85:3:6:6)%, and F3 (77:3:10:10)%. The cookie sample was then analyzed for water content, ash, iron, folic acid, cobalt, and antioxidant activity. The differences between the samples were analyzed based on the activity of antioxidants, iron, folic acid, and vitamin B12 (cobalamin) in data obtained from triplicates using multivariate ANOVA analysis.

Results: The results of the ash and water content tests of all three cookie formulations showed values in accordance with the Indonesian National Standard (SNI) for cookie products. F3 has significantly higher iron, folic acid, and cobalt levels than F1 and F2 (p<0.05). Antioxidant activity is highest in F3, but there is no statistical difference between F2 and F3 (p>0.05).

Conclusions: The combination of porang's tubers, moringa leaves, and tempe made from black soybeans, especially F3, has the potential to be used as a functional cookie processed product source of iron (Fe), folic acid, cobalamin, and antioxidants for adolescent anemia.
Long-term management of Graves disease: a narrative review
Authors: Kim Hyo-Jeong
Published: November 2022

Graves disease (GD) is the most common cause of hyperthyroidism, accounting for more than 90% of cases in Korea. Patients with GD are treated with any of the following: antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, or thyroidectomy. Most patients begin treatment with ATDs, and clinical guidelines suggest that the appropriate treatment period is 12 to 18 months. While RAI treatment and surgery manage thyrotoxicosis by destroying or removing thyroid tissue, ATDs control thyrotoxicosis by inhibiting thyroid hormone synthesis and preserving the thyroid gland. Although ATDs efficiently control thyrotoxicosis symptoms, they do not correct the main etiology of GD; therefore, frequent relapses can follow. Recently, a large amount of data has been collected on long-term ATDs for GD, and low-dose methimazole (MMZ) is expected to be a good option for remission. For the long-term management of recurrent GD, it is important to induce remission by evaluating the patient’s drug response, stopping ATDs at an appropriate time, and actively switching to surgery or RAI therapy, if indicated. Continuing drug treatment for an extended time is now encouraged in patients with a high possibility of remission with low-dose MMZ. It is also important to pay attention to the quality of life of the patients. This review aimed to summarize the appropriate treatment methods and timing of treatment transition in patients who relapsed several times while receiving treatment for GD.
Occupational allergic respiratory diseases - occupational asthma
Authors: Kopiec Dominika , Kuzioła Karolina
Published: November 2022

Introduction and objective: Occupational diseases, most often caused by allergens or irritants in the workplace, lead to a deterioration in the quality of life of employees and, in some cases, the inability to continue working in a specific position.It is important to prevent respiratory diseases, which will allow for earlier detection of changes and appropriate treatment. The aim of the study is to present the knowledge about occupational asthma on the basis of available scientific data, and to indicate appropriate preventive measures to reduce the incidence of this disease entity.

Review methods:While writing the thesis, a database was used, ie Pubmed and Google Scholar.

Brief description of the stage of knowledge: The group of the most common obstructive pulmonary diseases is bronchial asthma. This disease affects over a dozen percent of the population of civilized countries, and it affects various age groups and various social strata. Bronchial asthma can be mild, severe, and even fatal [1]. Occupational asthma is caused by inhaling antigens, which are abundant in the working environment of farmers, bakers and millers, including protozoa and airborne fungi.

Summary: Allergic respiratory diseases are a significant problem in the work environment. In addition, an increase in these diseases has been observed in recent years. It is related to the improvement of diagnostic methods, as well as their more frequent occurrence [2]. The frequency and type of allergy occurrence depends on many factors. These factors include genetics, exposure to aeroallergens, and the type of work performed. Certain professions are associated with a particularly high risk of allergic respiratory disease. Such occupations include a baker, miller, and employees in the transport industry [3].
Traditional and academic medicine – around the WHO strategy
Authors: Wrześniewska-Wal Iwona
Published: November 2022

The aim of the work is to show the strategy of the World Health Organization (WHO) according to which various ways of improving health are currently being sought, including knowledge, skills and practices based on theories, beliefs and experiences indigenous to various cultures. The problem is significant because out of 194 WHO member states, 170 reported the use of these practices by patients, but only 124 of them have adequate legal regulations. However, for patients, in addition to the law, evidence, data and scientific analysis are needed that these practices are effective and safe. And the doctor who provides health services is obliged to apply current medical knowledge and relies on objective criteria. Otherwise, they are exposed to the charge of infringement of the rules of conduct and sanctions. The article shows the direction of WHO's activities regarding the use of traditional medicine.
Supplemental information for "Evaluating the Hydrologic and Water Quality Impacts of the Revised SCS CN Method and Its Implications on Decision-Making"
Authors: Weikel Jamie , Karki Ritesh , Cibin Raj
Published: November 2022

Supplementary information showing the original and revised curve number, watershed characteristics of the study watershed, and code revisions for representing the revised curve number method in Soil and Water Assessment Tool (SWAT).
Hydrogeophysical Characterization of Swine Effluent Amended Soils in Mantled Karst
Authors: Fields Jon , Halihan Todd , Vilcaez Javier , Sharpley Andrew N. , Daniels Mike
Published: November 2022

Highlights

Animal effluents can be detected in soils after minimal applications using non-intrusive characterization techniques.

Swine effluent in soil produces measurable electrical signatures in the absence of chemical signatures.

Electrical resistivity imaging can determine soil thickness and identify rapid transport pathways in the subsurface.

Dietary additives may be good proxies to detect swine effluent in soils.

Abstract. Land application of animal manures is useful for increasing many beneficial properties of soil that include fertility, productivity, and overall soil health, but can pose risks to water quality if not properly applied, especially in karstic formations. A study was carried out to assess the use of electrical resistivity and soil sampling to better characterize the transport of applied swine effluent within a mantled karst system and to assess the potential for rapid transport of swine effluent represented by Zn and other metals commonly found in effluent. This hydrogeophysical investigation was conducted at three sites, all permanent pastures, along Big Creek near Mount Judea, AR, USA, that are underlain by the Boone Limestone formation that is home to the Buffalo National River. To determine if surface electrical geophysics could be utilized to monitor the applied swine effluent within a mantled karst riparian system, this study measured the bulk electrical properties of the subsurface, characterized soil properties at the surface, and used reactive transport modeling. Electrical resistivity imaging (ERI) showed soils at sites with applied effluent were more electrically conductive than a background site. A comparison of ERI and soil sampling bulk datasets demonstrated strong trends between bulk resistivity and fluid conductance. These results enabled a more accurate definition of soil characteristics, the epikarst zone, and bedrock, along with anticipated subsurface chemical transport. Keywords: Electrical Resistivity Imaging, Epikarst detection, Soil characterization, Swine Effluent.
Rare Case of Non-tuberculous Mycobacterial Infection following Repair of Pectoralis Major Avulsion: Case Report and Review of Literature
Authors: Kulkarni Siddhesh , Menon Aditya , Rodrigues Camilla , Soman Rajeev , Agashe Vikas M
Published: November 2022

Introduction: Non-tuberculous mycobacteria (NTM) infections of the musculoskeletal system are commonly missed due to their rarity and the absence of systemic symptoms. Here, we present a rare case of NTM infection following repair of an avulsed pectoralis major tendon in an immunocompetent host managed by a multi-disciplinary team specializing in musculoskeletal infections. Case Report: A 23-year-old male patient presented with discharging sinus in the right axilla for 6 months. He sustained the right pectoralis major muscle avulsion following an accident which was surgically repaired using FiberWire® and endo buttons. He developed a discharging sinus 4-month post-surgery. He presented with persistent infection in spite of empirical antibiotics elsewhere. Radiographs and MRI sonogram showed intra-medullar endo buttons in the proximal humerus with marginal pus collection in the axillary region with minimal medial extension into pectoralis major and minor muscles along the superior aspect. A detailed plan was made with inputs from a multidisciplinary bone infection team. Wound was radically debrided, implants and sutures removed, humerus scraped, and tissues sent for microbiology and histopathology. Extended incubation of deep tissue culture as suggested by ID specialists grew Rapidly growing mycobacteria, a type of NTM 3 weeks after surgery. Patient was started on intravenous amikacin along with oral clarithromycin and linezolid based on antibiotic susceptibility. Wound discharge persisted for almost 5-week post-surgery and stopped 2 weeks after initiation of appropriate antibiotics. Amikacin was given for 1 month and oral antibiotics were continued for 6 months. The pectoralis major function was unaffected after surgery and patient returned to normal activities 3 months after debridement. Patient has an infection free follow-up of 4 years. Conclusion: This case outlines the importance of having a high degree of suspicion for the diagnosing orthopedic NTM infections. In addition, it showcases the advantages of having good communication between surgeons, infectious disease specialist, and microbiologist for achieving good functional outcomes.
Novel Technique for the Management of Fibrous Dysplasia of Radius Shaft with Fibular Strut Autograft without Internal Fixation: A Case Report
Authors: Patankar Hemant , Gupta Devanshu , Memon Zaid , Memon Fayaz
Published: November 2022

Introduction: Fibrous dysplasia (FD) is a developmental disorder in which the normal bone arrow is distorted and replaced by dense fibrous stroma containing a disorganized matrix. The disorder can be localized to a single bone or affect multiple bones. Although any bone can be affected, the bones of the upper extremity are the rare site of involvement. The disease process results in deformity of the bones and is often complicated by pathological fractures. Case Report: Here, we present a case of a 14-year-old girl, who presented with FD of the radius bone with the progressive deformity with terminal restriction of supination and pronation. Radiographs showed revealed an expansile lytic lesion with ground glass appearance involving the proximal meta-diaphysis of the right radius, with its resultant bowin. Using Henry’s approach, we treated with an innovative surgical approach envisioned with the non-vascularized cortical fibular bone graft without an internal fixation. Conclusion: For the management of FD of radius bone, non-vascularized cortical fibular bone grafting provided if tightly fitted gives good radiological and functional outcome without any recurrence with complete osseointegration.
A Reminder for Chronic Ankle Pain: Case Report of Talar Osteoid Osteoma with Late Diagnosis
Authors: Vahabi Arman , Özbek Rıza Berker , Taşkıran Emin
Published: November 2022

Background: Talus osteoid osteomas are often overlooked. This pathology, which can cause chronic ankle pain, should be kept in mind when evaluating differential diagnoses. Case Report: A 21-year-old female applied to our clinic with chronic ankle pain diagnosed as talus OCD. The patient’s pain was refractory to non-operative treatments. The detection of talar osteoid osteoma is delayed due to atypical radiologic findings and coexistent osteochondral lesion of talus. The patient is treated with ankle arthroscopy with excellent results. Conclusion: Chronic ankle pain causes severe functional limitations. Dealing with such cases especially in the young population, one should consider that atypical radiologic signs could have further meaning. When radiology fails to describe the lesion, ankle arthroscopy could be a good option, both for diagnosis and treatment.
Biblioteques patrimonials a Catalunya (2020-2021)
Authors: Caballer Albareda Gemma , Moré Laura , Muxella Imma , Nicolau Payàs Anna
Published: November 2022

En aquesta edició de l’Anuari analitzem el paper que han tingut les biblioteques i centres patrimonials durant la pandèmia de la COVID-19 que, encara amb més força que en períodes anteriors, ha situat les persones en el centre d’atenció. L’anàlisi de les accions que es van dur a terme permet afirmar que han estat molt actives i han engegat múltiples projectes que han fet possible l’accés a les seves col·leccions i que han augmentat la seva presència a Internet. D’una banda, s’ha pogut constatar la renovació dels seus llocs web, que han afavorit l’accés a les biblioteques digitals i, de l’altra, la creació i difusió de continguts nous i el suport a la publicació de diferents materials, des d’articles científics fins a documentals o altres productes audiovisuals. Finalment, la presència a les xarxes socials i els projectes transversals han crescut durant aquest període i es presenten com a línies que es consoliden.
Un modelo pre-westfaliano de soberanía confederal: el “Concierto Político” vasco
Authors: Zubiaga Garate Mario
Published: November 2022

Con la entrada en crisis del modelo westfaliano, surgen dos tendencias contrapuestas en la concepción de la soberanía. Por un lado, se exacerban las dimensiones más duras de la soberanía estatal, pero, por otro, parecen adquirir carta de naturaleza modelos políticos pre-westfalianos de soberanía que pueden responder de forma adecuada a las demandas democráticas de las comunidades sub-estatales. Nos referimos a las fórmulas políticas que dieron cauce a modelos segmentarios de soberanía compuesta o fragmentada, modelos que en determinados lugares impidieron el pleno desarrollo de los dogmas westfalianos relativos a la unidad y supremacía del poder soberano del Estado. Modelos que no por casualidad entroncan con las fórmulas más avanzadas del federalismo. En concreto, en el caso español, las propuestas de reforma estatutaria planteadas recientemente por el soberanismo vasco recuperan el viejo (con)federalismo basado en los derechos históricos, conjugándolo con las más modernas concepciones federales y democráticas de la soberanía basadas en el derecho a decidir.
The chronology and rotational kinematics in the South-Eastern Jaca Basin (Southern Pyrenees): Las Bellostas section
Authors: Pueyo Emilio Luis , Rodríguez-Pintó Adriana , Serra-Kiel Josep , Barnolas Antonio
Published: November 2022

Despite the large number of magnetostratigraphic studies in the South Pyrenean Basin aiming to calibrate the basin chronostratigraphy and the biostratigraphic scales, the South Eastern Jaca Basin remains unexplored from this perspective, and its relation with the Ainsa Basin is not fully understood. In this work we contribute with new magnetostratigraphic data from the 950m thick Las Bellostas section, located in the northern hinge of the Balzes anticline. Well-proven primary signal (positive fold test and two pseudo-antiparallel polarities) supported by numerous primary data in the surroundings allow us building a reliable local polarity sequence of eight magnetozones (from R1 to N4). Additionally, seven new biostratigraphic samples (Nummulites and Assilina) in the lower part of the section (marine environment) allows tightening the section to the Geomagnetic Polarity Time Scale (GPTS) and proposing a refined age model for the southeastern Jaca Basin. The section starts in the Boltaña Fm., of Cuisian age (Shallow Benthic Zone, SBZ11), is followed by a sedimentary gap from C22n to C20n as witnessed by biostratigraphic data (SBZ11 underneath the hiatus and SBZ16 just atop). The deltaic Sobrarbe Fm. can be tracked until the C19n (Late Lutetian). From this point (200m) until the top of the section (950m), at least, the entire C18n chron can be recognized within the molassic Campodarbe Fm. (C18n.2n-C18n.1r and C18n.1n) (Bartonian) equivalent to the West to the prodeltaic Arguis marls Fm. The Middle Cusian (SBZ11) to Middle Lutetian (SBZ15) stratigraphic hiatus is, in part, enhanced by the structural position at the hinge of the Balzes anticline. These new chronostratigraphic constraints help refining the W-E and N-S stratigraphic relationships in the eastern Jaca Basin and in the Ainsa Basin. This section also allows us to accurately refine the kinematics of the rotational activity in the eastern External Sierras. The important difference in magnetic declination along the section and neighboring paleomagnetic data from the Balzes anticline (from ≈70º clockwise at the base of the stratigraphic section to non-significant at the top) together with the new age model for the Eastern Jaca Basin help characterizing the rotational activity of the Balzes thrust sheet. The rotation took place between chrons C20r (Middle Lutetian; 45Ma) and C17 (Lower Priabonian 37-38Ma) in agreement to nearby structures (Boltaña, Picodel Aguila anticlines) but clearly diachronic to western ones (Santo Domingo anticline). Besides, the rotational activity seems to follow a linear and continuous pattern (velocity 9-11º/Ma, R: 0.83-0.96) in contrast to closer structures that show two distinct rotational velocities (i.e. Boltaña). These new data still let open the debate on the rotational kinematics along the South Pyrenean basal thrust.
Coronavirus y puerperio: la matrona vuelve a casa
Authors: Ferrer-Romero Emilio , Sánchez-Larrosa Ana Isabel
Published: November 2022

Introducción. La pandemia por Covid-19 ha supuesto una reestructuración de los servicios sanitarios a nivel mundial. En el caso de las matronas en Cataluña, ha requerido que estas vuelvan a realizar puerperios a domicilio de manera sistemática, debido a la imposición de altas hospitalarias precoces en el posparto para evitar contagios por el virus. Objetivos. La siguiente investigación analiza las prácticas asistenciales, emociones y discursos de una matrona que realizó visitas posparto a domicilio en la provincia de Barcelona durante los meses de abril del 2020 a mayo de 2021. También se exploran las relaciones que la matrona establece con la mujer puérpera y su familia en medio de unas medidas de control extraordinarias. Material y métodos. Investigación cualitativa con un enfoque y métodos etnográficos mediante un estudio de caso. Se realizaron 10 entrevistas semiestructuradas de forma virtual a una misma matrona. Resultados y conclusiones. Como principales resultados se extraen la satisfacción de las mujeres y la matrona por las prácticas asistenciales de la visita en el domicilio, a pesar del miedo, que es una emoción continua en el discurso de ésta. Se muestra la complejidad de las intervenciones de la matrona en un contexto de pandemia y se justifica la necesidad de restablecer los puerperios precoces en el domicilio por los beneficios bio-psico-sociales que comportan a la madre y al bebé más allá de la época Covid-19.
Polarization dehazing method based on separating and iterative optimizing airlight from the frequency domain for different concentrations of haze
Authors: Sun Rui , Liao Tanbin , Fan Zhiguo , Zhang Xudong , Wang Changxiang
Published: November 2022

Polarization technology has been widely used in imaging through a scattering medium. However, the existing polarization dehazing methods are unstable because they require manual selections of polarization correction parameters. In addition, most of them only focus on the spatial domain without utilizing the frequency domain features, so their dehazing performances are insufficient. In this paper, we propose a polarization dehazing method based on separating and iterative optimizing airlight from the frequency domain. By separating the low-frequency sub-bands of polarization images and refining them as the airlight at three states, we calculated the Stokes parameters of airlight and obtained the preliminary dehazed image. We also propose an iterative optimization approach between the high-frequency sub-band of the dehazed image and airlight to effectively improve the dehazing performance. As a by-product, we introduce our real-world polarization datasets collected in different concentrations of haze. Both the qualitative and quantitative experiments show that our method is effective and robust in different concentrations of haze.
Design of a single-mode fiber coupling system based on the modified Gerchberg–Saxton algorithm
Authors: Qiao Jiawei , Shen Jiajia , Jiang Ping , Caiyang Weinan , Yang Huajun
Published: November 2022

The efficiency of a hollow beam received by the Cassegrain antenna
coupling into a single-mode fiber is low, and converting the hollow
beam into a solid beam can remarkably improve the coupling efficiency.
In this paper, shaping diffractive optical elements (DOEs) are
designed through a modified Gerchberg–Saxton algorithm (MGS) with
Fresnel diffraction. Further, the MGS algorithm can be applicable in
the issue of circular symmetric beam shaping. The properties of the
system with/without shaping DOEs are analyzed and compared. According
to the simulation results, in consideration of the energy loss of the
antenna, DOEs, and coupling lens, the total transmission efficiency of
the receiving antenna system at 1550 nm wavelength can reach
77.81%. In addition, the system with shaping DOEs can better adapt for
coupling lenses with different focal lengths, and the variation of the
maximum coupling efficiency of the DOEs shaping system at different
focal lengths studied in this paper is within 2.00%, which is 6.73%
lower than that of the lens shaping system. The research results
provide an idea of reverse design for improving a coupling system,
which can also provide inspiration for other optical system
designs.
Modeling of a ring-core trench-assisted few-mode BDFA for seven-mode signal gain equalization
Authors: Wang Dingchen , Pei Li , Zheng Jingjing , Wang Jianshuai , Xu Wenxuan , Li Jing , Ning Tigang
Published: November 2022

In this paper, a ring-core trench-assisted few-mode bismuth-doped fiber amplifier (BDFA) is simulated on the basis of the three-energy level. The fiber is designed to support four modes of signal group transmission for practical considerations, including LP01, LP11, LP21, and LP31. The results suggest that (1) it is possible to obtain gain equalization of the three signal groups by using the LP21 mode pump independently, where the maximum difference in modal gain (MAX DMG) is about 0.9 dB, except for the LP31 mode signal; (2) by combining the LP01 and LP31 mode pumps, the average gain of the groups increases by 14%, and the MAX DMG decreases by nearly 60% (3.8 to 1.5 dB) compared to the LP01 pump alone; and (3) with the same combination of mode pumps, the ring-core BDFA (1.5 dB) achieves better gain equalization than the single-core BDFA (2.8 dB). The analysis is informative for the future development of a multimode BDFA.
Energy Efficient Coupling-based ITO based Integrated Photonics Modulator
Authors: Patil Chandraman , Dalir Hamed , Wang Hao , Sorger Volker J.
Published: November 2022

Here, a high-speed optical modulator with large bandwidth, robust athermal operation, complementary metal-oxide-semiconductor (CMOS) compatibility, and using the magical critical coupling loss, is presented for photonics integrated systems and computing applications.
Polarization dependence of laser damage growth features on multilayer dielectric mirrors for petawatt-class lasers
Authors: Diop Saaxewer , Chorel Marine , Ollé Alexandre , Roquin Nadja , Lavastre Éric , Gallais Laurent , Bonod Nicolas , Lamaignère Laurent
Published: November 2022

PETAL (Petawatt Aquitaine Laser) is an ultrahigh-power laser dedicated
to academic research that delivers sub-picosecond pulses. One of the
major issues of these facilities is the laser damage on optical
components located at the final stage. Transport mirrors of the PETAL
facility are illuminated under different polarization directions. This
configuration motivates a thorough investigation of the dependency of
the laser damage growth features (thresholds, dynamics, and damage
site morphologies) on the incident polarization. Damage growth
experiments were carried out in s- and
p-polarization at 0.8 ps and 1053 nm on
multilayer dielectric mirrors with a squared top-hat beam. Damage
growth coefficients are determined by measuring the evolution of the
damaged area for both polarizations. In this Letter, we report higher
damage growth threshold in p-polarization together with higher damage initiation
threshold in s-polarization. We also
report faster damage growth dynamics in p-polarization. The damage site morphologies and their
evolution under successive pulses are found to strongly depend on
polarization. A numerical model in 3D was developed to assess
experimental observations. This model shows the relative differences
in damage growth threshold even if it is not able to reproduce the
damage growth rate. Numerical results demonstrate that damage growth
is mainly driven by the electric field distribution which depends on
the polarization.
Optimization of Bragg soliton dynamics for enhanced supercontinuum generation in ultra-silicon-rich-nitride devices [Invited]
Authors: Cao Yanmei , Sohn Byoung-Uk , Choi Ju Won , Sahin Ezgi , Chen George F. R. , Ong Kenny Y. K. , Ng Doris K. T. , Eggleton Benjamin J. , Tan Dawn T. H.
Published: November 2022

Bragg-soliton dynamics in a 2-stage ultra-silicon-rich-nitride (USRN) chip-based device, consisting of a cladding-apodized modulated Bragg grating (CMBG) stage and a USRN channel waveguide stage, is studied and optimized for enhanced supercontinuum generation. We observe that the enhancement is strongly dependent on the Bragg-soliton effect temporal compression developing in the CMBG stage, which is linked to both device and input pulse parameters. With the optimal parameter combination, a supercontinuum spanning 610 nm at the −30 dB level is experimentally demonstrated in the 2-stage USRN device, representing a 5× enhancement compared to that in a reference waveguide. Good agreement is obtained between the experimentally measured supercontinuum and simulations based on the generalized nonlinear Schrödinger equation and is consistent with design rules based on Bragg soliton compression. This device provides an encouraging path to generate supercontinuum in compact chip-based platforms, which does not need ultrashort, femtosecond scale pulses, greatly relaxing the pulse width and pulse power requirement.
Inter-annual variations of vegetation dynamics to climate change in Ordos, Inner Mongolia, China
Authors: Jia Xiru , You Guangyong , McKenzie Shawn , Zou Changxin , Gao Jixi , Wang Anlan
Published: November 2022

To reveal the characteristics of climate change and the controlling factors for vegetation dynamics in the Ordos, Inner Mongolia, China, 34 years (1982–2015) of regional climate variables and vegetation dynamics were investigated. The results show that: Annual mean air temperature (TMP) significantly increased with a linear slope of 0.473°C/10yr. Annual precipitation (PRE) had a non-significant positive trend nearly 5 times lower than the trend of potential evapotranspiration (PET). The average Normalized Difference Vegetation Index (NDVI) computed for the region was found to show a significant positive trend (6.131×10−4/yr). However, all climate variables displayed non-significant correlations with NDVI at annual scale. The reduction of desert and the increase of grassland over the past decades were accountable for the increased NDVI. Principal components analysis revealed that the regional climate change can be characterized as changes in temperature, humidity and the availability of radiant energy. Based on principal components regression coefficients, NDVI was mostly sensitive to humidity component, followed by growing season warmth (WMI). Spatially, 93.1% of the pixels displayed positive trend and 61.8% of the pixels displayed significant change over the past decades. Both principal regression analysis and partial correlation analysis revealed that NDVI in eastern part of Ordos was sensitive to TMP, whereas, NDVI in southern and western areas of Ordos displayed the high sensitivity to combined effects of PRE and cloud coverage (CLD). Partial correlation analyses also revealed that TMX was a surrogate for aridity, TMN was a representative of humidity, and temperature variations below the threshold of 5°C (CDI) were less important than WMI. We conclude that regional climate change can be characterized by warming and increased aridity. The significant positive trend of regional NDVI and the non-significant correlations between NDVI and climate variables at annual scale suggests the hidden role of the human activities.
Drinking and swimming around waterways: The role of alcohol, sensation-seeking, peer influence and risk in young people
Authors: Leavy J. E. , Della Bona M. , Abercromby M. , Crawford G.
Published: November 2022

The role of individual and sociocultural factors contributing to drowning risk for young adults is complex and poorly understood. This study examined the relationship between behaviour in and around waterways and: 1) alcohol consumption; 2) resistance to peer influence; 3) sensation-seeking; 4) perception of risk among people aged 15–24 in Western Australia. A cross-sectional online survey was conducted at three time-points with a convenience sample. Predictor variables included: Alcohol Use Disorder Identification Test Consumption (AUDIT_C); Resistance to Peer Influence; Brief Sensation Seeking scale; Benthin’s Perception of risk. Pearson chi-squared tests determined the association between demographic and predictor variables. Logistic regression explored influence of potential predictor variables on behaviour in and around water. The final sample (n = 730) participants, consisted of females (n = 537, 74.5%), metropolitan dwelling (n = 616, 84.4%), and attended university (n = 410, 56.9%). Significant associations were found for those who swum after drinking alcohol compared with those that had not by age, gender, education. For every 1-unit increase in AUDIT-C participants were 60% more likely to swim after drinking (OR 95% CI 1.60 1.44–1.78). Participants who considered an adverse event serious were 15% less likely to have swum after drinking alcohol (OR 0.85 95% CI 0.73–0.99). The complex relationship between social participation in activities in and around waterways, higher drowning rates, propensity for risk, and the meaning young adults attach to risk locations and practices present unique challenges for drowning prevention research. Findings should be used to improve the awareness and education components of future youth water safety strategies in high-income settings.
Fractional transit compartment model for describing drug delayed response to tumors using Mittag-Leffler distribution on age-structured PKPD model
Authors: Byun Jong Hyuk , Roh Yunil , Yoon In-Soo , Kim Kwang Su , Jung Il Hyo
Published: November 2022

The response of a cell population is often delayed relative to drug injection, and individual cells in a population of cells have a specific age distribution. The application of transit compartment models (TCMs) is a common approach for describing this delay. In this paper, we propose a TCM in which damaged cells caused by a drug are given by a single fractional derivative equation. This model describes the delay as a single equation composed of fractional and ordinary derivatives, instead of a system of ODEs expressed in multiple compartments, applicable to the use of the PK concentration in the model. This model tunes the number of compartments in the existing model and expresses the delay in detail by estimating an appropriate fractional order. We perform model robustness, sensitivity analysis, and change of parameters based on the amount of data. Additionally, we resolve the difficulty in parameter estimation and model simulation using a semigroup property, consisting of a system with a mixture of fractional and ordinary derivatives. This model provides an alternative way to express the delays by estimating an appropriate fractional order without determining the pre-specified number of compartments.