bluuebunny/crossref_metadata_2025 huggingface dataset:
The hydration of fast setting spray binder versus (aluminum sulfate) accelerated OPC
Authors: Briendl Lukas G. , Mittermayr Florian , Röck Rudolf , Steindl Florian R. , Sakoparnig Marlene , Juhart Joachim , Iranshahi Fatemeh , Galan Isabel
Published: February 2022

The (early) hydration mechanisms of two different binder systems used for shotcrete were investigated: the so far almost unexplored low sulfate binder (spray binder), used in the field of dry-mix shotcrete; and ordinary Portland cement, accelerated by aluminum sulfate, widely used for wet-mix shotcrete. The basis for the fast setting of the spray binder is the rapid dissolution of C3A and the subsequent formation of flaky CO3-AFm phases. Thereby induced high aluminum concentrations in the pore solution lead to a blockage of alite dissolution during the first hours of hydration. At later stages, higher amounts of portlandite are formed in the dry-mix, compared to the wet-mix system. The lower calcium availability for portlandite formation in the wet-mix system is explained by an enhanced formation of C–A–S–H phases with a higher Ca:Si ratio. Additionally, wet-mix systems show lower porosity and higher compressive strength after 1 d of hydration and beyond.

Graphical abstract
The touch of words : obscure spatial encounters
Authors: Heimonen Kirsi
Published: February 2022

This article addresses the touch of words on corporeality in reading, performing, and writing in an artistic research project. Here, touch refers to forms of listening, perceiving, moving, and writing triggered by Finnish people’s written memories and experiences concerning mental hospitals. The article, which forms part of the outcome of a multidisciplinary research project titled Engraved in the body, is based on the effects on the researcher of reading these written accounts. Through their inexplicable touch, their obscurity, these memories have haunted, fascinated, and driven the artist-researcher to perform and write in a way which, while not ‘knowing’ anything, nevertheless acknowledges the unpredictable affective touch of memories. This has led the writer and performer to experience infinite spatialities in which conscious acts are replaced by the resonance of memories, generating in turn a kind of non-personal corporeality for transmitting something in them that is hidden or inexpressible through traces of their touch on corporeality. Throughout the process of reading these memories, the continuous practice of a somatic movement technique, the Skinner Releasing Technique (SRT), with its poetic vocabulary and notion of the spatiality of corporeality enabled exposure and attunement to the quality of the written memories of others and to the silence beyond them. Alongside SRT, this article draws specifically on the insights of Maurice Blanchot and Jean-Luc Nancy to articulate the lived relation between corporeality, language, and writing.
Auf das richtige Tragen der richtigen Masken kommt es an
Authors:   HyKoMed GmbH, Lünen, Popp Walter , Parohl Nina ,   HyKoMed GmbH, Lünen, Meyer Sabine ,   Kath. St. Paulus GmbH: St. Marien Hospital Lünen
Published: February 2022

Masken (chirurgischer Mund-Nasen-Schutz) werden seit 120 Jahren im Operationssaal (OP) eingesetzt und haben sich bewährt. Vor 20 bis 30 Jahren haben die Krankenhäuser angefangen, FFP(filtering face piece)-Masken zu verwenden, die im gewerblichen Bereich schon länger Standard waren. Sie wurden zunehmend zum Personalschutz bei bestimmten Infektionskrankheiten eingesetzt, zum Beispiel bei der Versorgung von Grippe- oder Tuberkulosekranken. Der Umgang mit den FFP-Masken galt dabei immer als einfach und sicher, eine Maskenauswahl oder Schulung gab es nicht. Die Erfahrungen mit der Corona-Pandemie zeigen, dass dies eine große Fehlannahme war.
Pflegekräfte mit Hautproblemen in der Pandemie
Authors:   Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW), Abt. Arbeitsmedizin, Gefahrstoffe und Gesundheitswissenschaften (AGG), Hamburg, Westermann Claudia , Zielinski Nika ,   Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen (IVDP), Competenzzentrum Epidemiologie und Versorgungsforschung bei Pflegeberufen (CVcare), Universitätsklinikum Hamburg-Eppendorf (UKE), Kleinmüller Olaf ,   Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen (IVDP), Competenzzentrum Epidemiologie und Versorgungsforschung bei Pflegeberufen (CVcare), Universitätsklinikum Hamburg-Eppendorf (UKE), Nienhaus Albert ,   Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen (IVDP), Competenzzentrum Epidemiologie und Versorgungsforschung bei Pflegeberufen (CVcare), Universitätsklinikum Hamburg-Eppendorf (UKE), Altenburg Christiane ,   Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW), Abt. Arbeitsmedizin, Gefahrstoffe und Gesundheitswissenschaften (AGG), Hamburg, Dulon Madeleine ,   Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW), Abt. Arbeitsmedizin, Gefahrstoffe und Gesundheitswissenschaften (AGG), Hamburg
Published: February 2022

Der folgende Beitrag beschreibt eine Studie zur Häufigkeit von Hautirritationen durch das Verwenden von persönlicher Schutzausrüstung während der Covid-19-Pandemie in Deutschland. Wie belastet ist das Pflegepersonal? Welche Empfehlungen zur Prävention werden diskutiert?
Wie beurteilen BGW-Präventionsberatende den Umgang mit Desinfektionsmitteln in Praxen, Kitas und Friseursalons?
Authors:   Freiburger Forschungsstelle Arbeits- und Sozialmedizin (FFAS), Freiburg, Michaelis Martina , Stößel Ulrich ,   Freiburger Forschungsstelle Arbeits- und Sozialmedizin (FFAS), Freiburg, Gerding Johannes ,   Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW), Köln, Nienhaus Albert ,   Competenzzentrum Epidemiologie und Versorgungsforschung bei Pflegeberufen (CVcare), Universitätsklinikum Hamburg-Eppendorf
Published: February 2022

Wie wird der Arbeits- und Infektionsschutz in Bezug auf Desinfektionsmittel seit Beginn der Covid-19-Pandemie gelebt? Im folgenden Beitrag wird über die Erfahrungen von sechs Präventionsberatenden der Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege (BGW) bei ihren Besuchen von Kleinst- und Kleinbetrieben verschiedener Branchen berichtet. Die Erfahrungen wurden in leitfadengestützten narrativen Interviews zusammengetragen.
A precise gene delivery approach for human induced pluripotent stem cells using Cas9 RNP and recombinant AAV6 vectors v1
Authors: Chupradit Koollawat , not provided nontaphat.tho , Tayapiwatana Chatchai , not provided methichit.wat
Published: February 2022

Genome editing in human induced pluripotent stem cells (hiPSCs) offers a potential tool for studying gene functions in disease models and correcting genetic mutations for cell-based therapy. Precise transgene insertion in hiPSCs represents a significant challenge. In the past decade, viral transduction has been widely used due to its high transduction efficiency; however, it can result in random transgene integration and variable transgene copy numbers. Non-viral-based strategies are generally safer but limited by their low transfection efficiency in hiPSCs. Recently, genome engineering using adeno-associated virus (AAV) vectors has emerged as a promising gene delivery approach due to AAVs’ low immunogenicity, toxicity, and ability to infect a broad range of cells. The following protocol describes the workflow for genome editing in hiPSCs using CRISPR/Cas9 ribonucleoproteins (RNPs) combined with the recombinant AAV serotype 6 (AAV6) donor vectors to introduce a gene of interest (GOI) fused with mCherry fluorescent reporter gene into the AAVS1 safe harbor site. This approach leads to efficient transgene insertion and is applicable to precise genome editing of hiPSCs or other types of stem cells for research purposes.
Untargeted Top-down Proteomics byLC-MS/MS on Eclipse v1
Authors: Drown Bryon , Camarillo Jeannie , Melani Rafael , Kelleher Neil
Published: February 2022

Describes the LC-MS/MS data acquisition procedure for top-down proteomics samples using the Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
Tropical Soil Bacterial Diversity in Sabah, Malaysia
Authors: Chin Lai Mun , Clemente Michael Wong Vui Ling
Published: February 2022

Bacteria are an essential biological component of soil function that plays fundamental roles in biogeochemical cycling, soil quality improvement, habitat-shaping, and ecosystem conservation. It is therefore important to have a good record of soil bacteria in the tropics in order to monitor future changes that may occur due to global warming and other factors. However, extremely limited data are available on the diversity of bacteria in soils in some tropical Borneo regions such as Sabah, Malaysia. This research, therefore, was undertaken to determine the bacterial diversity of soils from various locations in Sabah, Malaysia. Ten soil samples (n=10) were collected around Sabah. 16S rDNA of bacterial DNA extracted from soils were amplified and analysed using the Denaturing Gradient Gel Electrophoresis (DGGE). A total of 100 dominant and well-defined DNA fragments observed in the DGGE gel were extracted, sequenced, and aligned. The results indicated that 93 different bacterial operational taxonomic units (OTUs) representing bacteria from 8 different phyla were present. The most abundant phyla in the analysed Sabah soils were Proteobacteria followed by Acidobacteria, Firmicutes, Actinobacteria, Planctomycetes, Verrucomicrobia, Chloroflexi, and Bacteroidetes. The examined soils of Sabah and Peninsular Malaysia had similar dominant phyla in general, except that the most dominant phylum in Peninsular Malaysia soils is the Acidobacteria instead of Proteobacteria. These baseline data generated from this work are important and can be used to track bacterial diversity shifts due to soil or environmental changes in the future.
Green Synthesis of Nickle Oxide Nanoparticles for Adsorption of Dyes
Authors: Rashid Israa Muzahem , Salman Sami Dawod , Mohammed Alaa Kareem , Mahdi Yasmin Salih
Published: February 2022

The green synthesis of nickel oxide nanoparticles (NiO-NP) was investigated using Ni(NO3)2 as a precursor, olive tree leaves as a reducing agent, and D-sorbitol as a capping agent. The structural, optical, and morphology of the synthesized NiO-NP have been characterized using ultraviolet–visible spectroscopy (UV-Vis), X-ray crystallography (XRD) pattern, Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM) analysis. The SEM analysis showed that the nanoparticles have a spherical shape and highly crystalline as well as highly agglomerated and appear as cluster of nanoparticles with a size range of (30 to 65 nm). The Scherrer relation has been used to estimate the crystallite size of NiO-NP which has been found about 42 nm. The NiO-NPs have subsequently used as adsorbents for adsorption of two types of dyes; methylene blue (MB) as cation dye and methyl orange (MO) as anion dye. The removal efficiency of dyes from contaminated water was investigated during various key parameters at room temperature; initial dye concentration (Co), pH, contact time (t), agitation speed, and adsorbent dosage. The maximum removal of MB dye was found to be 96% (Co=25 mg/l, pH=10, contact time=100 min, agitation speed=300 rpm and adsorbent dosage=6 g/l), while for MO the maximum removal reached 88% at (Co=20 mg/L, pH=2, contact time=160 min, agitation speed=300 rpm and adsorbent dosage=6 g/L). The experimental adsorption data were found to well obey Freundlich isotherm. The kinetic investigation showed that the adsorption process for both dyes followed a pseudo-second-order model with rate constants 0.0109 and 0.0079 (mg/g min) for MB and MO, respectively.
Impact Behaviour of Aluminum Particles upon Aluminum, Magnesium, and Titanium Substrates using High Pressure and Low-Pressure Cold Spray
Authors: Manap Abreeza , Mahalingam Savisha , Yusof Siti Nurul Akmal , Afandi Nurfanizan , Abdullah Huda
Published: February 2022

This study is focused on the impact and residual stress behaviour of aluminum component repair using aluminum powder via two different types of cold spray processes; high pressure cold spray (HPCS) and low-pressure cold spray (LPCS). It has been carried out via smoothed particle hydrodynamics simulations, comparing aluminum substrate with other lightweight materials such as titanium and magnesium. The obtained results have shown that the impact behaviour is influenced by velocity, porosity, deformation behaviour, flattening ratio, total energy and maximum temperature. The aluminum particles impacting on aluminum substrates using LPCS is slightly deformed, with the smallest flattening ratio leading to less pore formation between the particles. This has subsequently resulted in good coating quality. Furthermore, HPCS has contributed greatly to the deposition of particles on the heavier and harder substrate, such as titanium substrate. Thus, the overall result indicates that LPCS is better for repairing aluminum component compared to HPCS.
Criminal Law Signs of a Criminal Community (Criminal Organization) and their Correlation with the Signs other Forms of Complicity
Authors: Demchuk S. D.
Published: February 2022

The paper, based on the interrelated provisions of Art. 35 and Art. 210 of the Criminal Code of the Russian Federation, examines the criteria for distinguishing such a form of complicity as a criminal community (criminal organization). The study has taken into account the diversity of points of view of domestic scientists who covered the problematic issues of the content and qualification of organized criminal activity. In the context of the Decree of the Plenum of the Supreme Court of the Russian Federation of June 10, 2010 No. 12 “On judicial practice in considering criminal cases on the organization of a criminal community (criminal organization) or participation in it” and a number of court decisions, the author determines the most typical features of this criminal association. Based on the analysis of the stages of constructing a criminal community (criminal organization), there is a low probability of qualifying the interrupted creation of this form of complicity as an unconsummated crime. The main practical difficulty lies in establishing and proving its integral criminal-legal aspects (signs) at all stages of formation. This applies, firstly, to the evaluation sign of the stability of a group of persons (their consolidation), which is the basic characteristic of organized complicity. Secondly, a unified leadership of two or more organized groups or the presence in such a group of separate units that carry out their activities as part of a criminal community (criminal organization) is mandatory. Therefore, characterization of roles of its organizers and participants is possible only if the management hierarchy of the consolidated association of accomplices included in the structural divisions is proved, which, in turn, is associated with their activities to achieve the goals provided for in Part 4 of Art. 35 of the Criminal Code of the Russian Federation. Consequently, bringing the perpetrators to criminal liability under Parts 1 and 2 of Art. 210 of the Criminal Code of the Russian Federation is actually due to the proof of the preparation or commission of planned crimes by them as members of these groups.
Russian Legislation Development Prospects in the Field of Protection of Citizens’ Rights in Processing of Genetic Information (Private Law Outlook)
Authors: Boltanova E. S. , Imekova M. P.
Published: February 2022

The European Union countries tend to ensure the protection of citizens’ rights when processing genetic information in such areas as healthcare, science, labor and insurance. In Russia, such protection of citizens’ rights is provided exclusively for the prevention, disclosure and investigation of crimes.

The results of the study show that genetic information is an element of objects of various constitutional human and civil rights (for example, the right to health, the right to privacy, personal dignity, etc.). Consequently, it can be the object of a complex of legal relations of various areas of law: constitutional, civil, labor, etc. In this regard, it is concluded that the protection of the rights of citizens in Russia in processing of genetic information in such areas as healthcare, science, labor and insurance should have a complex (intersectoral) character. At the same time, there is no need to adopt a general law that would ensure the appropriate protection of citizens’ rights in all these spheres of society. It is enough to make point changes to the laws regulating public relations on processing of genetic information within a particular sphere. The Federal Law «On Personal Data» should definitely take a central place among such laws. Its norms are of «cross-cutting» character and are subject to application to all public relations, one way or another related to the processing of genetic information.

In addition, there is a sphere of social life in Russia that is directly related to the processing of genetic information, but is not subject to legislative regulation. This is scientific research that uses biological samples of human origin. The authors of the paper, by analogy with the legislation of the European Union, propose to adopt a new Federal Law «On research of biological samples of human origin».
Implementation of a Process Approach to the Quality of Expert Legal Assistance in the face of Digitalization
Authors: Gavrilov S. N.
Published: February 2022

Digital transformation of legal profession and advocacy involves finding, selecting, and developing approaches that ensure the translation of data about objects, connections, and processes of the real (analog) world related to the relevant subject area into a virtual (digital) format. Therefore, it is very important that the description of the properties of objects, connections and processes subject to digitalization should be machine-readable, and the «pre-digital» (analog) image of such should fit into the paradigm of information technology (Information Technology, IT) for the subsequent transformation of this image into digital form.

The digital transformation of legal profession and advocacy is not an end in itself. The key issue is the quality of expert legal assistance. The issue of the quality of expert legal assistance must be addressed on a systematic basis, taking into account such quality management functions as quality planning, quality assurance, quality control, and quality improvement. The development of the topic of quality (proper quality) of expert legal assistance involves the formation of a certain theoretical model on an appropriate methodological basis, followed by its implementation in the regulatory (regulatory) framework of the ecosystem of advocacy and implementation in corporate practice. The author offers one of these models. The model is based on the so-called process approach. The paper describes the essence of the process approach, the process model of the quality of the expert legal assistance itself and gives a general description of its elements. The process model allows you to look at the provision of expert legal assistance through the prism of the process approach used in IT: it makes it possible to plan the provision, provide and analyze the results of the rendered expert legal assistance in the paradigm of this approach. The author notes the high analytical potential of the process model of the quality of qualified legal aid and its practical usefulness.
Bactericidal properties of urine against BK. Pr. Med. 932, 19
Authors: Kramov N.
Published: February 2022

Courmont, Gardre, examining the urine of TBK patients and healthy people for its bactericidal properties, came to the following conclusions: the urine of non-TB patients does not possess bactericidal properties against VC in cultures; on the contrary, the urine of TBK patients is bactericidal. But that the property of urine is weaker than the bactericidal action of pleural effusions and blood serum. It can be assumed that the bactericidal activity of the urine of TBK patients comes from that of the blood serum.
Tooth decay during radical surgery of the maxillary cavities., D-r Hall e (Arch. F. Ohr., Nas und Kehlkopfheilkunde. B. 126. H. 3 / 4.1930. Oktober)
Authors: Viktorova E. S.
Published: February 2022

The author recommends the method developed by him for penetration into the Highmore cavity from the side of the nasal passage instead of the usual opening it (according to the method of Caldwell-Luc'a, Denker'a) 'in which it is necessary to remove a lot of healthy bone with damage to the vessels and alveolar nerves of the upper jaw, after which patients suffer from toothaches for more or less a long time; for this purpose, a hole is made in the lateral wall of the lower nasal passage, through which the cavity becomes accessible for viewing, and, if necessary, for surgical interventions.
About skin wear in flax spinners
Authors: Potashnik M. B.
Published: February 2022

According to the reports of the insurance office for a number of years, the incidence of skin and subcutaneous tissue accounted for a significant percentage of the total number of days of disability among workers at the Lenin Flax Mill.
Regarding the calcium content in the blood of glaucomatous patients
Authors: Nechkina-Brodovskaya K. V.
Published: February 2022

The work of Chiari and Januschке establishes the inhibitory effect of calcium salts on transudation and exudation. These researchers proved by their experiments that the extremely severe oedema of the connective membrane of the rabbit's eye caused by mustard oil or Auburn quickly disappears if the animal is injected subcutaneously or intravenously with a few cubes of calcium salt solution. Similarly, in dogs poisoned with sodium iodide or thiosinamine, the onset of profuse pleural exudate, pulmonary edema and hydropericardium can be prevented by application of calcium salts. This is also confirmed by other authors (Leo, Levy, Heubner, Rona, etc.).
Blood neutrophils and changes in their functional activity in case of shockogenic injuries
Authors: Sabitova A. M.
Published: February 2022

Phagocytic reactions occupy one of the central places in the regulation of homeostasis and play an important role in the formation of pathological processes. Of particular importance among the latter is shock, which develops with powerful aggressive effects on the body and is accompanied by significant structural and functional changes that cover all systems, including phagocytic ones. By origin and structural and functional features, all phagocytic cells are divided into microphages (neutrophils) and macrophages (alveolar, Kupffer cells, monocytes, etc.).
Joachim Romanovich Petrov (1893-1970)
Authors: Badyugin I. S.
Published: February 2022

On December 23-24, 1993, a scientific conference was held at the St. Petersburg Military Medical Academy (VMedA): "Actual problems of the pathophysiology of extreme conditions", dedicated to the 100th anniversary of the birth of Academician of the USSR Academy of Medical Sciences, Major General of Medical Service I.R. Petrov, Head of the Department of Pathological Physiology of the Medical Academy of Medical Sciences (1939-1963), Professor-Consultant of the Military Medical Academy (1963-1968), Chairman of the All-Union Society of Pathophysiologists (1960-1968), Honorary Chairman of this Society (1968-1970).
Stovarsolan treatment for syphilis in children
Authors: Batunin M. P.
Published: February 2022

At the present time there is already a number of works, both laboratory and clinical-experimental, partly appeared in the press, partly reported at congresses and meetings of scientific societies - works performed with stovarsolan Aniltrest, and characterizing preventive and therapeutic value of this drug. Indications for its use are all forms of syphilis, contraindications - decompensated heart defects, nephritis of non-syphilitic origin, serious disorders of the gastrointestinal tract, far advanced pulmonary tbc, severe general exhaustion if not directly caused by syphilis, finally, organic (non-syphilitic) sufferings of the eye and auditory nerves.
Treatment of gonorrhoids with lysovakina. Gershkovich and Shapiro (Ven. and Derm., 1928, No. 1)
Authors: Yasnitsky N.
Published: February 2022

Gershkovich and Shapiro recommend the treatment of gonorrhoids with lysovakina. It is known that Emmerich and Lw showed by their studies that a special substance, pyocyanase, capable not only of stopping the growth of this bacillus but also of causing lysis of other microbes, is formed in a 3-4-week-old broth culture of Pseudomonas bacillus. These studies initiated attempts to use pyocyanase for therapeutic purposes in a number of infectious diseases, including gonorrhea. The authors set out to test the therapeutic value of the lysovaccine in the treatment of gonorrheal diseases.
Experiments with myosalvarsan. Planner (Wien. klin. Woch., 1927, No. 48)
Authors: Weinstein A.
Published: February 2022

The author subjected to a clinical trial a new preparation of salvarsan for intramuscular administration recently released by Rolle, Myosalvarsan. The drug is administered intramuscularly in the sciatic area, the dosage is the same as for neosalvarsan. Thirty-one patients of various ages and stages of syphilis, including some patients with congenital syphilis, were treated with this drug.
On conservative surgery in acute purulent osteomyelitis
Authors: Ratner Yu. A.
Published: February 2022

The nature and size of surgical intervention in severe surgical patients are determined primarily by the patient's general condition and the reserve of his vitality. Acute osteomyelitis belongs to the number of severe sufferings, affecting most often the growing children's body, and is rightly called a typhoid of bones. In the clinical picture of this disease, sometimes even before the appearance of local symptoms, severe septic conditions come to the fore. Particularly severe is often acute multiple osteomyelitis. In most cases it is a generalized septic disease with one or more deep metastases and circulating infection in the blood.
Etiology of endemic goiter. Huguenin (Presse med., 1928, No. 28)
Authors: Znamensky M.
Published: February 2022

Goiter develops due to exaggerated physiological growth processes depending on various factors, - here the influence of sex (predominance of females 5:1-3), stages of sexual life (maturation, pregnancy, childbirth), heredity (to the 4th generation) and, finally, the "water" factor affects. It has been proven experimentally that deficiency of salts and, in particular, of iodine does not play a role in goiter etiology.
Malaria treatment
Authors: Sherman S. I.
Published: February 2022

At present, quinine, salvarsan, methylene blue, iodine are mainly used for treatment of malaria, and recently there have been reports of magic action of plasmoquine and plasmoquinine. Each of these remedies is used by different authors in different doses and modifications, and each writes about the advantage of his own way of using one or another drug.
Stovarsol in poorly developing infants. Tezner (Mon. f. Kindheil., Bd. 34, H. 1)
Authors: Makarov Y.
Published: February 2022

The author was convinced that giving it in an amount of 1/2 to 2 tablets a day (up to 25 tablets in 3 weeks) could cause weight gain in hypotrophics, who, although receiving sufficient food, did not gain weight. Interested in the cause of weight gain in his experiments, the author investigated the basic metabolism when given stovarsol, as well as the excretion of water and salts, and, finding no explanation in either experiment, suggested a decrease in perspiratio insensibilis as the cause of weight gain.
On the possibility of treating edema by the method of "dry" immersion
Authors: Yunusov M. A. , Vinokhodova T. V. , Gerasimov G. A.
Published: February 2022

The results of the use of therapeutic "dry" immersion (LSI) in the complex therapy of 10 patients with refractory edematous syndrome of various etiologies are presented, and the effect of the method on some indicators of central hemodynamics is studied. It has been established that LSI sessions lasting from 2 to 6 hours potentiate the action of diuretic drugs and help compensate for the condition of patients. LSI session has a positive effect on central hemodynamic parameters.
Spinal anesthesia. J. Ducuing (Presse méd., 1927, No. 77)
Authors: Znamensky M.
Published: February 2022

Since 1908 the author has performed 6000 lumbar anesthesias. On the basis of his experience he establishes the following contraindications to the latter: 1) age under 15 and over 70 years old; 2) short-term operations, or those which can be done under local anesthesia; 3) former or present nervous system disorders; 4) low blood pressure (from this point of view spinal anesthesia is contraindicated in bleeding, general peritonitis, shock and infections). The author also does not use it in breast surgeries.
Treatment of uterine bleeding with diuretics. R. Wermer (Zentr. f. Gyn., 1928, No. 11)
Authors: Zabolotskaya E.
Published: February 2022

The author suggests using diuretics for uterine bleeding on the following grounds: it is known from numerous experiments on patients with diabetes insipidus that pituitaryrin reduces diuresis; the posterior pituitary gland, which is the site of pituitaryrin production, plays an important role in regulating the water content in the body - its task is to protect the body from too much water loss; if a large amount of water is extracted from the body, the pituitary gland begins to produce pituitrin intensively to inhibit further water withdrawal.
Loss-Based Performance Assessment and Seismic Network Optimization for Earthquake Early Warning
Authors: Böse Maren , Papadopoulos Athanasios N. , Danciu Laurentiu , Clinton John Francis , Wiemer Stefan
Published: February 2022

The goal of earthquake early warning (EEW) is to issue an alert before the damaging seismic waves of an earthquake hit a given exposure. We develop a framework to evaluate the EEW performance in a loss-based context. We use warning time as a key performance indicator and determine statistics of warning time by loss severity to assess the rate and consistency with which an EEW system can deliver timely alerts. In the second part of this work, we develop a Genetic Algorithm approach to optimize an existing sensor network by proposing sites for new stations to enhance the EEW performance in damaging earthquakes. We demonstrate this framework for Switzerland using 2000 realizations of a 50-yr-long stochastic earthquake catalog, which samples the earthquake rate forecast of the Swiss Hazard Model in space and time. For each of the almost 24k earthquake scenario ruptures (5.0 ≤ M ≤ 7.4), we predict shaking intensities and losses (here, fatalities and injuries) at the largest Swiss cities. We find that the current Swiss Seismic Network could provide positive warning times to the affected sites for about 80% of very damaging earthquakes (≥100 fatalities) and for around 85% of earthquakes with ≥10 fatalities. Warning times of >5 s could be achieved for about 40%–55% of very damaging earthquakes and >10 s for about 35%. For around 50% of events with ≥1 fatality (≥10 injuries), EEW could provide >15 s of warning. The greatest benefit of EEW is expected in Zürich, where the population density and, consequently, absolute long-term expected losses are highest and the warning times for damaging earthquakes are often long (>15 s). Densifying the Swiss Seismic Network with additional stations can increase warning times in selected scenarios by up to 5 s. However, because it is already very dense (7 ± 5 km interstation distance), decreasing data latencies (currently ∼2 s) may be more important.
A global synthesis on pyroentomology and a special focus on ground beetle (Coleoptera: Carabidae) community and functional trait responses to prescribed fire severity
Authors:   , Mason Stephen C. , Gelhaus Jon K
Published: February 2022

In the field of pyroentomology, there is a mix of conflicting positive and negative results on how insect communities respond to fires. Many studies show that fires benefit certain taxa, but in contrast, many other studies show that fires can detriment that same taxa. Thus, I conducted a systematic literature search and meta-analyses for butterflies (Lepidoptera: Rhopalocera), bees (Hymenoptera: Apoidea), and ground beetles (Coleoptera: Carabidae) and report how each taxa's richness and abundance responded to overall fire and 16 different fire and site characteristics (e.g., severity, seasonality). Additionally, I conducted field work in the New Jersey Pinelands to study how different prescribed fire severities impacted surface active ground beetle taxonomic richness, abundance, and community composition, as well as functional richness and functional community composition. The results from the meta-analyses across 100 studies and 445 effects showed that each taxon responded differently between each other from overall fire, and within taxa, their richness and abundance varied from different fire and site characteristics. Furthermore, I did not find any fire and site characteristics that decreased richness across taxa. Surprisingly, I also found that only 7% of pyroentomology studies quantified fire severity. For my ground beetle research in the NJ Pinelands, I collected 447 specimens represented by 18 genera of 23 species and 10 functional trait groups during 2017 and 2018 across our middle and high severity and unburned, control sites. My results showed that high prescribed fire severity decreased ground beetle abundance the first year of the fire, but recovered during the second year. I also found that middle and high prescribed fire severity had no detrimental effects on taxonomic and functional richness. Lastly, I found that both taxonomic and functional community compositions were unique by fire severity treatments and control, by year, and combining treatments and year together. In conclusion, aiming for high prescribed fire severity, at least in the NJ Pinelands, will benefit surface active ground beetles. Most importantly though, methodically quantifying fire severity will provide more accurate results within study, and thus, help solve the conflicting pyroentomology results between studies.
Stable Isotope Analysis of Giant Clam Shells
Authors:   , Gannon Michelle Elizabeth , Velinsky David J.
Published: February 2022

Giant clams (Tridacninae) are important mollusks in Pacific and Indo-Pacific coral reefs. Like coral, they host a photosymbiotic relationship with zooxanthellae, which provide essential nutrition increasingly through life. Their shells are often isotopically assessed as [delta]18O values are used to reconstruct sea surface temperature. Yet, values of [delta]13C are not frequently reported or discussed but may provide insights to the ambient dissolved inorganic carbon. Additionally, values of [delta]15N and [delta]13C from shell-bound organic material may offer unique perspectives on the dietary shift from filtered particulate material to photosynthate from zooxanthellae. First, values of [delta]13C are compared between the inner (IL) and outer shell layers (OL) of ten Tridacna to gain an understanding of differences within the individual, those living together and across three species. Typically, [delta]13C values do not differ in the IL of contemporaneous specimens while those of the OL do. This suggests the [delta]13C values of the IL represent values closer to ambient DIC and may experience less isotopic fractionation. Next, to apply these results, profiles of [delta]13C values from the IL of ten Tridacna collected between 1857 and 1992 are presented in combination with profiles from literature through time. Since 1841, 13C has become depleted in the IL by approximately 1.5[per mille], reminiscent of that of [delta]13C from atmospheric CO₂ from Mauna Loa Observatory. A positive relationship between both [delta]13C systems suggests Tridacna are a good record of the Suess Effect. Finally, the organic shell matrix is isotopically assessed by decalcification. Bioeroding organisms present in these samples introduced isotopic contamination. It is hypothesized that sequential extraction of organic material would initially remove bioeroding organisms to ultimately reveal isotope values of the giant clam, however there was no significant isotope shift through extraction time. Bioerosion is predicted to be exacerbated by ocean acidification and global climate change, emphasizing the need for enhanced water quality management. This work highlights the untapped potential for environmental assessment and reconstruction utilizing stable isotopes in three parts of the giant clam shell (IL; OL; organic matrix). With enhanced technology and water quality management, these results provide a framework for future studies.
Graves‘ disease in children and adolescents in Iceland
Authors:   Faculty of Medicine, Department of Health Sciences, University of Iceland, Reykjavík, Þórsson Þórbergur Atli , Bjarnason Ragnar ,   Faculty of Medicine, Department of Health Sciences, University of Iceland, Reykjavík, Childrens Hospital Hringurinn, National University Hospital of Iceland, Reykjavík, Jónasdóttir Soffía Guðrún ,   Domus Medica, Reykjavík, Jónsdóttir Berglind ,   Childrens Hospital Hringurinn, National University Hospital of Iceland, Reykjavík
Published: February 2022

INTRODUCTION: Graves‘ disease is an autoimmune disease in which autoantibodies cause an increase in the production of thyroid hormones, and is the most common cause of thyrotoxicosis in children. Symptoms in children are often more obscure than in adults. The aim of the study is to assess the incidence of Graves’ disease in children and adolescents in Iceland over the span of two decades (2001-2021), and furthermore to investigate if the incidence rate has increased, as well as to describe treatment options and disease recurrence. MATERIAL/METHODS: This retrospective descriptive study included all children diagnosed with Graves‘ disease in the years 2001-2021 in Iceland. Information was obtained from the Directorate of Health‘s drug database and from ICD-10 diagnoses at Landspítali – The National University Hospital. RESULTS: In total, 57 children and adolescents were diagnosed with Graves’, the overall incidence rate was 3.5/100,000 person-years. Gender ratio was 1:2.7 (male : female) and the mean age at diagnosis was 13.6 for boys and 13.9 years for girls. Of those 12 individuals currently receiving drug therapy (21.8%), four patients have had disease relapse. Thirteen patients reached an euthyroid state with medication (23.7%), 25 received treatment with radioactive iodine (45.5%) and 5 underwent surgery (9.1%). Boys were more likely to relapse. Disease recurrence was 31.8%. CONCLUSION: The incidence of Graves‘ disease did not increase during the study period. The disease was more common in girls, although the gender ratio was lower than expected. Antithyroid drugs were the first choice in treatment and radioactive iodine was the most common permanent treatment option. Disease recurrence was common. A possible relationship between the duration of the original drug therapy and disease recurrence should be investigated.
Comparative study of hysteroscopy with ultrasonography and its correlation with histopathology in cases of abnormal uterine bleeding in perimenipausal women
Authors: Upadhyay Ayushi , Tyagi Mamta , Gupta Smriti , Bansal Rani , Varma Yamini
Published: February 2022

Background: The aim was to compare the diagnostic efficacy of ultrasonography (USG) and hysteroscopy in detecting uterine abnormalities in abnormal uterine bleeding (AUB) by correlating the results with histopathological examination.Methods: This prospective study was conducted among women attending gynecological OPD of Subharti medical college, Meerut over a period of two years from October 2019 to August 2021. A total of 100 perimenopasual women with AUB attending obstetrics and gynaecology OPD were included in this study. All patients underwent transvaginal scan to note down the endometrial thickness and to rule out uterine and adnexal pathology. All the patients underwent diagnostic hysteroscopy, followed by a biopsy of the endometrium using a curette. The endometrium was sent to the pathologist. Findings of these diagnostic modalities then correlated.Results: Out of 100 women, USG detected that 54 patients (54%) had no pathology and 46 patients (46%) had abnormal findings, out of which maximum patients, 29 patients (63.04%) had endometrial hyperplasia. According to hysteroscopy, 46 patients (46%) had normal hysteroscopic findings while 54 patients (54%) had abnormal findings of which maximum were 18 patients (33.33%) who had endometrial hyperplasia. Histopathology findings revealed that 47 patients (47%) had normal findings and 53 patients (53%) had abnormal findings out of which maximum patients 20 (37.7%) had endometrial hyperplasia. In our study of 100 women with AUB, on USG only 1 patient had endometrial malignancy and the same was reported by hysteroscopy and histopathology.Conclusions: In our study hysteroscopy proved to be highly sensitive and specific considering histopathology as gold standard. Ultrasonography has good sensitivity and specificity but less as compared to hysteroscopy.
Breast location of tuberculosis: a case report and literature review
Authors: Mian Dehi Boston , Loue Vedi Andre Serges , Angoi Aya Virginie , Yao Alexis , Kouyate Mohamed , N' guessan Koffi , Boni Serge
Published: February 2022

Breast tuberculosis (TB) is a rare localization of extra-pulmonary TB. We report the first case observed in our daily activities to show the difficulties in the diagnosis and the good evolution in the treatment. In spite of the fact that it is rare, breast TB should not be ignored, especially in a country with high TB endemicity.
Twin pregnancy with a coexisting mole: case report
Authors: V. Divya , Sivakumar Sudha , T. Preetha
Published: February 2022

Twin molar pregnancy with a coexisting live fetus and a hydatidiform mole is a rare form of the gestational trophoblastic disease associated with increased risk of obstetrical complications and poor perinatal outcome. Prenatal diagnosis is essential for couple counselling and follow-up in tertiary care centers. The incidence ranges from 1 in 20,000 to 1 in 1,00,000 pregnancies. Management of such cases is tough because the possibility of fetal survival should be weighed against the risk of complications of molar pregnancy. A case of twin molar pregnancy and a coexisting live fetus diagnosed at 15 weeks using ultrasound is described from obstetrical management to a post molar follow-up.
Efficacy of topical vancomycin application in cardiac surgery to reduce deep sternal wound infection: a randomised control trial at tertiary cardiac care hospital
Authors: Shah Soham J. , Jadhav Uday E.
Published: February 2022

Background: Mediastinitis is lethal complication and a challenge in post cardiac surgery patients. We aim at evaluation of topical vancomycin by applying it at sternal edge in prevention of deep sternal wound infection.Methods: The vancomycin group had local application of vancomycin paste prepared by mixing 1gm of powder in 3 ml of normal saline and stirred until paste was formed. The control group had reinforced closure technique without vancomycin paste application. All cases were followed up for symptoms and signs of sternal wound infection during hospital stay and uptil 1 month.Results: There was increase incidence of wound infection with control group as compared to vancomycin group, there were no wound infection in patients of vancomycin group.Conclusions: Application of topical vancomycin significantly reduces post-sternotomy wound infection and prevents deep mediastinitis.
A comparative study on ultrasound guided percutaneous aspiration versus incision and drainage in the management of small breast abscesses
Authors: Voruganti Mohan R. , Sistu Manoj K. , Gadipudi Hamika C.
Published: February 2022

Background: A breast abscess is either lactational or non-lactational with the former being more common. Lactational breast abscess is more common in younger age and primipara. It occurs mostly during the first 6 weeks of lactation. A non-lactating breast abscess is usually secondary to diabetes, tuberculosis, smoking, or an underlying breast pathology. Traditional treatment of breast abscess is by incision & drainage. It causes a lot of psychological pressure on already stressed lactating mothers. Recent trends for the treatment of small breast abscesses favor minimally invasive procedure using needle aspiration under USG guidance with adjuvant antibiotics. It is now the preferred mode of treatment for small breast abscess over open surgical incision and drainage.Methods: A comparative prospective study of 50 cases of small breast abscesses less than 5cm was done using both surgery and aspiration. 25 cases were studied in each group. Follow up was done and results were tabulated.Results: Aspiration shows better results. It has the advantage of treatment under local anesthesia as a day case. Recovery (92%) is as good as open surgery. Healing is without a scar and does not need painful dressings. The drawbacks are sometimes it needs repeated aspirations and not suitable for large abscesses.Conclusions: Aspiration under ultrasonographic guidance should be first line of treatment for small (<5cm) breast abscesses.
Metastatic melanoma of the gallbladder in a patient with acute cholecystitis: a case report and review of the literature
Authors: Sawyer Emily , Tran Kayla , Kalpakos Lydia , Ratnayake Sujith
Published: February 2022

Melanoma is an aggressive type of cancer that has significant metastatic potential. Most commonly, distant melanoma metastases are identified in the lung, liver and brain. Metastatic melanoma of the gallbladder is extremely rare and is usually associated with widespread gastrointestinal deposits which purports a poor prognosis. Whilst an uncommon site of melanoma metastases, it accounts for 50% of all tumour metastases to the gallbladder. There are a small number of case reports and case series that describe different manifestations of melanoma metastases to the gallbladder. We report the case of a patient who presented with acute cholecystitis on a background of cholelithiasis and underwent a laparoscopic cholecystectomy with histopathology identifying gallbladder metastasis from malignant melanoma.
Transanal excision of anorectal leiomyoma, a rare location pathology: case report and review
Authors: Bustamante Silva Ludwigvan Adriano , Velasco Cabrera José Antonio , Aguilar Barragán Cuauhtémoc , Ruiz Berrones Arianna , Jaimes Durán Edwin Michel , Gallardo Castillo Andrés Manuel , Cazarez Huazano Sinue
Published: February 2022

Gastrointestinal leiomyomas (GILM) are benign tumors truly originated in the smooth muscle of the digestive tract, therefore, they are mesenchymal tumors and can come from the muscularis propria, muscularis mucosae or from the smooth muscle of the blood vessels. These tumors occur more frequently in women and despite being the second most common mesenchymal mural tumor of the digestive tract, anorectal location is very rare, representing less than 0.1% of all anorectal neoplasms. In the present case, we reported a patient with a rectal submucosal leiomyoma that was excised using a transanal approach.