bluuebunny/crossref_metadata_2025 huggingface dataset:
PERAN PEMIKIRAN FATIMA MERNISSI DALAM MEMAHAMI ISLAM DAN KEMODERNAN DI MAROKO
Authors: Taufik Muhammad
Published: November 2023

Abstract: This article discusses Islam and modernity in a country in North Africa, Morocco. The research question is how is Islam and modernity in Morocco and their relationship to the fate of women in the perspective of Fatima Mernissi? From the results of this study, it was found that between Islam and modernity in Morocco is something that has not meet expectations. According to Mernissi, there is still marginalization of women in the socio-political and religious aspects of life in Morocco. Because it is related to the interpretation of religion, Mernissi said that there is a need for a hermeneutical and socio-historical approach that adapts to the context, Islam for her is always actual in its development, including in this modern era. What is new from this research is that Islam and modernity in Morocco have not gone hand in hand, although times have changed, they are still not in line. While the goal that the author wants to achieve in this paper is to complete the lack of studies that have ever existed about Mernissi's thinking whose emphasis is that modernity should be directly proportional to the fate of women who are equal to men.Keywords: Islam; Modernity; Morocco; Fatima Mernissi; Hermeneutik and Socio Historical Approach; Marginalization of Women Abstrak: Dalam artikel ini, kami menganalisis hubungan antara Islam dan modernitas di Maroko, sebuah negara di Afrika Utara, melalui lensa pemikiran Fatima Mernissi. Kami bertanya bagaimana Islam dan modernitas di Maroko dan hubungannya dengan nasib perempuan dilihat dari perspektif Mernissi. Melalui studi ini, kami menemukan bahwa hubungan antara Islam dan modernitas di Maroko belum sesuai dengan harapan. Menurut Mernissi, masih terdapat marginalisasi perempuan dalam aspek sosial-politik dan agama dalam kehidupan di Maroko. Karena ini terkait dengan interpretasi agama, Mernissi menyatakan bahwa diperlukan pendekatan hermeneutik dan sosio-historis yang sesuai dengan konteks. Menurutnya, Islam selalu relevan dalam perkembangannya, termasuk dalam era modern ini. Hasil baru dari penelitian ini adalah bahwa Islam dan modernitas di Maroko belum berjalan bersama-sama, meskipun zaman telah berubah, mereka masih tidak selaras. Tujuan dari penulis dalam artikel ini adalah untuk menyelesaikan kekurangan studi yang pernah ada tentang pemikiran Mernissi yang menekankan bahwa modernitas harus sebanding dengan nasib perempuan yang sama dengan laki-laki.Kata Kunci: Islam, Modernitas, Maroko, Fatima Mernissi, Pendekatan Hermeneutik dan Sosio-Historis, Marginalisasi Perempuan
URGENSI PEMBATASAN UMUR PERKAWINAN DALAM UNDANG-UNDANG NO 16 TAHUN 2019 TENTANG PERKAWINAN (PERSPEKTIF SADD ADZ-DZARÎ’AH)
Authors: Fadillah Nor
Published: November 2023

Abstract: The marriage constitution in the article 7 No 16 of 2019, “A marriage is only permitted if a man and a woman have reached the age of 19”. The age restriction in marriage is not clearly stated and determined in either Al-Qur’an or Hadis as it is stated in the constitution. So based on this issue, this research tries to examine the correlation of theory Sadd Adz-Dzari’ah on the article 16 of 2019 Marriage Age Restriction. This type of research is a normative legal research based on constitution and analytical approaches, then analyze it qualitatively. Based on the result of this research could be concluded that, the age restriction is not found technically written in the Al-Qur’an and Hadis, however it is said in the Al-Qur’an and Hadis to carry out the marriage when someone reaches the puberty and adequate enough to do so. The marriage which carried out by ignoring the age restriction will bring out some damage toward psychology, social, reproduction health, some risk at giving birth and divorce. The quality of those damages might be included as dzari’ah criteria which most likely (ghalabah dzhon) issue some harms and must be avoided is to restrict the age, age restriction is an important thing in the household life, because it’s one of the supporting factor to achieve the marriage purpose in which to build the sakinah mawaddah warahmah family.Keywords: The Correlation of Age Restriction; Marriage. Abstrak: Undang-Undang Perkawinan pada pasal 7 No 16 Tahun 2019, “Perkawinan hanya diizinkan apabila pria dan wanita sudah mencapai umur 19 tahun”. Pembatasan umur dalam perkawinan ini tidak disebutkan dan ditentukan secara jelas dalam nash, maka dari sinilah penelitian ini berangkat, yakni berusaha untuk mengkaji korelasi teori Sadd Adz-Dzari’ah  terhadap Undang-Undang  No 16 Tahun 2019 tentang pembatasan umur perkawinan, Jenis penelitian ini adalah hukumnormatif dengan pendekatan Undang-Undang dan analitis dan menganalisisnya secara kualitatif. Hasil dari penelitian ini yaitu pembatasan umur dalam perkawinan memang tidak ditemukan secara tertulis dalam Al-Qur’an dan Hadis, akan tetapi dalam Al-Qur’an dan hadis menyebutkan anjuran pernikahan untuk orang yang sudah baligh serta mampuuntuk menikah. Perkawinan yang dilaksanakan dengan mengabaikan pembatasan umur akan melahirkan dampak negatif yaitu dari segi psikologis, sosial, kesehatan reproduksi, resiko ketika melahirkan, dan perceraian. Kualitasdampak negatif tersebut termasuk kriteria  dzari’ah yang kemungkinan besar (ghalabah dzon) akan terjadi dan harusdicegah dengan cara memberikan pembatasan umur, pembatasan umur merupakan hal yang penting karena ia menjadi salah satu faktor yang mendukung tercapainya tujuan dari perkawinan yaitu membangun keluarga sakinah mawaddah warahmah.Kata Kunci: Korelasi Pembatasan Umur; Perkawinan.
PERMAINAN TRADISIONAL BALOGO PADA MASYARAKAT KALIMANTAN SELATAN DALAM KARYA SASTRA
Authors: Normuliati Sri , Urahmah Nida
Published: November 2023

Abstract: This study aims to describe the traditional game of the people of South Kalimantan called balogo in literary works. This study uses qualitative research with descriptive methods. The data collected are in the form of words, phrases, sentences, dialogues of the characters and paragraphs related to the depiction of the traditional balogo game. After the data is collected, the data will be analyzed using descriptive methods. In the analysis process, the research data obtained will be described in detail. After the data analysis process, the last activity is to provide conclusions on research results. From the research that has been done, obtained research results about: (1) The shape of the logo in the form of an animal or other shapes such as the shape of a kite, (2) The interaction of the characters in playing balogo related to the process of playing the logo, (3) Messages from balogo game to be careful when hitting the logo so that the logo that is hit does not enter other people's pages, and (4) The existence of the balogo game for children divides the story into two groups, namely the East Antasan children's group who plays the logo and the children's group Western Antasan who is not interested in playing logoKeywords: Traditional Games; Balogo; Literary Works. Abstrak: Penelitian ini bertujuan untuk menggambarkan permainan tradisional masyarakat Kalimantan Selatan yang bernama balogo dalam karya sastra. Penelitian ini menggunakan penelitian kualitatif dengan metode deskriptif. Data-data yang dikumpulkan berupa kata-kata, frasa, kalimat, dialog para tokoh dan paragraf yang berhubungan dengan penggambaran permainan tradisional balogo. Setelah data terkumpul, data akan dianalisis dengan menggunakan metode deskriptif. Pada proses analisis, data penelitian yang didapatkan akan dideskripsikan secara detail. Setelah proses analisis data, kegiatan terakhir adalah memberikan kesimpulan terhadap hasil penelitian. Dari Penelitian yang telah dilakukan, diperoleh hasil penelitian tentang: (1) Bentuk logo yang berbentuk binatang atau bentuk-bentuk lainnya seperti bentuk layang-layang, (2) Interaksi para tokoh dalam bermain balogo yang berkaitan dengan proses bermain logo, (3) Pesan dari permainan balogo agar berhati-hati dalam memukul logo agar logo yang dipukul tidak masuk halaman orang lain, dan (4) Eksistensi permainan balogo bagi anak-anak bagi dalam cerita yang terbagi menjadi dua kelompok, yaitu kelompok anak Antasan Timur yang memainkan logo dan kelompok anak Antasan Barat yang tidak tertarik bermain logo.Kata Kunci: Permainan Tradisional; Balogo; Karya Sastra.
Etiology of rhizome rot of asparagus (Asparagus officinalis) in Atenco, Mexico State
Authors: Gonzalez-Cruces Juan Agustin , Sandoval-Islas José Sergio , Nava-Díaz Cristian , Sandoval- Sánchez Maricarmen
Published: November 2023

The objective of this research was to identify the causal agent of asparagus rhizome rot, as well as evaluate different inoculation methods and the severity of the isolates. Sampling was carried out in five producing plots Atenco, Edo. from Mexico. Five isolates of Fusarium spp. were selected. (one per plot) to perform pathogenicity tests. Three isolates were selected for their colonization characteristics for severity tests with different inoculation methods: Immersion for 12 h, immersion for 30 min and inoculation by contact with absorbent paper soaked in 1 mL of inoculum. Concentrations of 1x106 conidia mL-1 were used. 10 rhizomes were used per treatment and 10 rhizomes without inoculation. To determine the severity, photographs (in GIMP®) of the rhizome were analyzed seven days after inoculation. The isolates were molecularly identified with ITS4/ITS5, EF688/EF1521 and TUBT1/BT2B. Fusarium prolifetatum was morphologically and molecularly identified in the three isolates. The P3DR isolate was the most severe (14.6%), followed by P5DR (13.9%) and P1SIR (11.6%). The most effective inoculation method was immersion for 30 min. They were registered in the NCBI Gene Bank with accessions ON738484 (P3DR), ON973801 (P5DR) and ON738483 (P1SIR). This is the first report of F. prolifetatum in the Edo. from Mexico.
Optimizing Pre-emergence Herbicide Oxyfluorfen Dose based on Its Sorption and Desorption for Effective Weed Management under Different Soil Types
Authors: Selvakumar S. , Chakravarthy K. Shoban , Baskar P. , Sangeetha C.
Published: November 2023

Background: Adsorption and subsequent release of pre-emergence herbicide into the soil solution decides the herbicide availability to kill the weeds. Herbicides applied on clay or organic rich soil type, absorb more results in lowering its availability in soil solution become sub lethal to kill the weeds, whereas sandy soil adsorb less and desorb more, sometime it increases the herbicide concentration to toxic level to crop. Effective weed control could be achieved by studying the variability of soil and deciding the dose based on the sorption and desorption properties of the soil. Methods: With this information on the background a laboratory experiment was conducted at the Department of Agronomy, Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai, India during 2021 to study the optimum level of oxyflourfen concentration in soil solution required to kill the weeds effectively. The study on sorption and desorption was carried out with pre-emergence herbicide oxyflourfen with five different concentrations in five different soil types. Result: The highest sorption of 98.53 per cent was observed with clayey soils followed by sandy clay loam soils with high organic matter content (96.97 per cent). The lowest sorption (77.96 per cent) was recorded with sandy loam soils. The highest desorption of 57.44 per cent was recorded with sandy loam soil and the lowest desorption percentage (13.18 per cent) was obtained with sandy clay loam soil with higher organic matter. Based on the analytical results of sorption and desorption, oxyflourfen dose was optimized as 0.53 kg ha-1 for sandy clay loam soils with high organic matter, 0.34 kg ha-1 for clay soil, 0.29 kg ha-1 for sandy clay, 0.21 kg ha-1 for sandy clay loam soil and 0.12 kg ha-1 for sandy loam soils. In conclusion, the clay soil required more quantity of oxyflourfen compared to other types of soil for effective management of weeds under irrigated condition.
Diversity and Relative Abundance of Insect Pollinators on Pigeon Pea (Cajanus cajan L.) in Gajapati District of Odisha
Authors: Padhy Deepayan , Satapathy Chitta Ranjan , Borkataki Shimantini , Shankar Tanmoy , Ray Soumik
Published: November 2023

Background: Many cross pollinated flowering plants rely on pollinators for reproduction and survival. The pigeon pea (arhar), Cajanus cajan L., is the India’s most important pulse crop. It attracts pollinators because to its cross pollination nature, possible nectar and pollen source, attractive colour and scent of the seeds and timing of blossoming. As a result, a complete research of pigeon pea insect pollinator fauna shall be used to conserve those fauna for increasing pigeon pea pollination effectiveness. Methods: Diversity of different pollinating agents associated with the crop pigeon pea by observing their abundance, diversity, percentage contribution, dominance status and diversity following the statistical diversity indexes were recorded during Kharif, 2021-22 in the state of Odisha where the insect pollinators’ fauna was recorded through fixed plot survey. Result: Megachille lanata (Fabricius) was found to be the most dominant pollinator throughout the flowering period among seven different pollinators of order Hymenoptera. M. lanata and Megachille disjuncta (Fabricius) shown higher foraging activity i.e. 6.02 bees/5 min/m2 and 4.25 bees/5 min/m2 respectively. Subdominant class represented maximum species among different dominant status classes exhibited. Very less diversity was observed throughout the season but still more diversity has been observed at mid flowering stags during 10:00-11:00 AM..
PARAMETRIC ANALYSIS OF NATURAL AIR EXCHANGE IN MULTI-APARTMENT RESIDENTIAL BUILDINGS
Authors: Deshko Valerii , Bilous Inna , Hetmanchuk Hanna
Published: November 2023

Most multi-apartment residential buildings built in the 20th century in Central and Eastern Europe do not meet modern energy efficiency requirements. The main part of the thermal energy consumed by buildings is used to heat the supply air from outside, which is the largest share in the energy balance of buildings. The purpose of this research is a parametric analysis of influencing factors on the frequency of air exchange in the room and an experimental study of the concentration of CO2 in a typical apartment. The object of the study is a one-room apartment in a family-type dormitory in the city of Kyiv. The dormitory has ducted natural ventilation. In the work, experimental measurements of the concentration of carbon dioxide were carried out in the premises of the living room, kitchen, corridor of the apartment and in the ventilation channel in the summer period. The indicator gas method was used to measure the air exchange rate. During air infiltration, the average rate of air exchange in the absence of people in the apartment in the living room was 2.41 h-1, in the corridor - 2.34 h-1, in the kitchen - 0.57 h-1. Under exfiltration conditions, the average values were lower: living room – 0.24 h-1, corridor – 0.94 h-1, kitchen – 0.52 h-1. The dependence between wind directions and the phenomena of infiltration and exfiltration in the premises of the apartment was recorded. As a result of the research, it was established that the most influential parameter of the change in the concentration of CO2 in the room is the release from people's breath. It follows from the simulation results that to ensure the regulatory level of CO2 concentration is not higher 1500 ppm, it is necessary to observe the air exchange in the considered room not lower than the level of 1.51 h-1 for conditions when 2 people are constantly in the room That is, the mass balance of CO2, which takes into account the number of inhabitants, can be an attractive alternative method for predicting the intensity of ventilation of a building.
Ukraine: The Scale and Problems of Migration
Authors: Komarovskiy V.
Published: November 2023

The problem of migration flows regulation as the main form of interaction between donor and recipient countries is becoming increasingly important in the context of the growing confrontation between globalism and multipolarity, the growth of the accompanying conflict and uncertainty. The growth in the volume of cross-border migration, the increase in the heterogeneity of its flows significantly increase the urgency of an in-depth analysis of migration flows. Ukraine is an important player in the labor force export market. In 2022 it also became a large-scale source of refugees. The correlation and mixing of these flows in the specific conditions of military-political confrontation is a real problem at the present stage of development. All this determines the practical significance of the proposed analysis.
Digital and Media Education of Adult Educators
Authors: Ratiu Mariana , Pele Alexandru Viorel , Bradea Adela , Pop Claudia Florina
Published: November 2023

This paper exposes the initial part of a research consisting in a need analysis carried out by the Romanian partner in the Erasmus+ "Media Education for Aware Adults" project, regarding digital competences and media education of adult educators or trainers. After a short introduction on the subject, in the paper are presented the main findings of the desk research, and two focus group sessions, first one for identifying the necessary digital competences of adult educators, and second one for identifying the elements that educators need in order to adequately support adults in their learning process, especially in relation to the digital environment. The results of the initial research will lead to the development of the main intellectual outputs, namely the digital competences framework, handbook, online platform and training material on digital and media education. In their development will be taken into account, on the one hand, the needs identified in the initial research, and, on the other hand, the need for a sustainable approach to all activities, resources and outputs produced, as well as education itself, this goal being assumed through the project.
Vulnerability and Inner Areas in Italy. “Should Young Stay or Should Young Go”?
Authors: Grignoli Daniela , D’Ambrosio Mariangela , Boriati Danilo
Published: November 2023

The essay focuses, from a sociological perspective, on the phenomenon of depopulation of Inner Areas in Italy. In this areas, younger generations, live a great inequality that exposed them to risk of social vulnerability. So, on the one hand, the desire to leave their community is growing among younger, on the other hand, the desire to deal with extreme adverse conditions is falling down. The research aims to explore the depopulation phenomenon in the context of Southern Italy, considering it as an emerging social vulnerability that impacts very deeply onto the sustainability of a social, economic and community systems such as the Molise region one. The following paper therefore presents an empirical web-survey conducted in the Molise region. The methodology used is Quantitative, and the research design is Exploratory. The essay underlines how proximity welfare can act as a flywheel to counter the depopulation Inner Areas of Italy enacted by the younger generations.
Influence of Fluvial Discharges and Tides on the Salt Wedge Position of a Microtidal Estuary: Magdalena River
Authors: Cordero-Acosta Jhonathan , Otero Díaz Luis J , Higgins Álvarez Aldemar E
Published: November 2023

The linkage between the salt wedge, tidal patterns, and the Magdalena River discharge is established by assessing the ensuing parameters: stratification (ϵ), buoyancy frequency (β), potential energy anomaly (φ), Richardson number (RL), and bottom turbulent energy production (P). The salinity, temperature, density, and water velocity data utilized were derived from MOHID 3D, a previously tailored and validated model for the Magdalena River Estuary. To grasp the dynamics of the river, a flow regime analysis was conducted during both wet and dry climatic seasons of the Colombian Caribbean. The utilization of this model aimed to delineate the estuary's spatial reach, considering flow rates spanning from 2000 to 6500 m³/s across two tidal cycles. This approach facilitates the prediction of the position, stability, and stratification degree of the salt front. Among the conclusions drawn, it is highlighted that: 1. The river flow serves as the principal conditioning agent for the system, inducing a strong estuary response to weather stations; 2. The extent of wedge intrusion and the river discharge exhibit a non-linear, inversely correlation; 3. Tidal waves cause differences of up to 1000 m in the horizontal extent of the wedge; 4. Widespread channel erosion occurs during the rainy season when the salt intrusion does not exceed 2 km; 5. Flocculation processes intensify during the transition between dry and wet seasons; 6. The stability of the salt layering and the consolidation of the FSI-TMZ are contingent upon the geometric attributes of the channel.
1-(2,5-Dimethoxy-4-nitrophenyl)piperidine and 1-(2,5-dimethoxy-4-nitrophenyl)pyrroridine
Authors: Syeda Tanjia M. , Al-Shaidi Muadh R. , Basri Ibtihal , Merzouk Mahboub , Aldabbagh Fawaz
Published: November 2023

Treatment of the non-purified mixture of dinitro isomers obtained from the nitration of 1,4-dimethoxybenzene with piperidine, led to the isolation of novel but minor adduct, 1-(2,5-dimethoxy-4-nitrophenyl)piperidine (2b) in 15% yield. Yields of nucleophilic aromatic substitution adducts are high when using purified 1,4-dimethoxy-2,5-dinitrobenzene (1b) with piperidine and pyrrolidine to give 2b and 1-(2,5-dimethoxy-4-nitrophenyl)pyrrolidine (3b) in 76% and 82%, respectively.
“I Genuinely Believe This Is the Most Stigmatised Group within the Social Care Sector.” Health and Social Care Professionals Experiences of Dealing with People with Alcohol Related Brain Damage: A Qualitative Interview Study
Authors: Kruithof Peter Johan , McGovern William , Haighton Catherine
Published: November 2023

Appropriate diagnosis, treatment and care contributes to better service engagement, improvements to wellbeing, cost savings, reductions in morbidity and mortality for people with Alcohol Related Brain Damage. In the North-East of England large amounts of alcohol are consumed, reflected in the number of alcohol-related deaths in the region. However, the pathway for people with Alcohol Related Brain Damage to receipt of diagnosis, treatment and care is unknown and could be unwittingly influenced by stigma. Qualitative in-depth semi-structured interviews were completed with 25 health and social care professionals from organisations involved with people with Alcohol Related Brain Damage recruited via snowball-sampling. Interviews were recorded, transcribed verbatim, coded, and analysed. People with Alcohol Related Brain Damage were stigmatised both by society and professionals which inhibited entry into services therefore Alcohol Related Brain Damage remained underdiagnosed and misdiagnosed. There was no dedicated service but silos with revolving doors and underfunded generic care with long waiting lists typically excluding those with alcohol or neurological problems. Professionals need to be challenged on the assumption that Alcohol Related Brain Damage is self-inflicted via training aimed at challenging unconscious bias. Reducing stigmatising processes associated with Alcohol Related Brain Damage could counteract professionals’ reluctance to provide care.
Discrete-Analog Low-Pass Filter Using Switched Capacitors With Resistive Pole Frequency Control
Authors: Butyrlagin Nikolay , Titov Alexey , Denisenko Daria , Ivanov Yuri
Published: November 2023

We offered the circuit of a discrete analog filter (DAF) low frequencies of second-order on switchable capacitors, which differs from the known ones in that three capacitors with one terminal are connected to a common bus, and the frequency of the DAF pole depends not only on the ratio of the capacitances of the frequency-setting capacitors, but also on the ratio of resistances two additional resistors in the feedback. This allows at constant values ​​of the capacitances and a fixed switching frequency of electronic switches, control the pole frequency by changing the resistance ratio of additional resistors. Computer simulation of the developed circuit was performed in the Micro-Cap environment. It has been established that the DAF has a transmission coefficient close to minus one at very low frequencies and a transmission coefficient close to zero at higher frequencies.
2D Graphene Structures for Safe Explosion Works Produced by Self-Propagation High Temperatures Synthesis
Authors: Voznyakovskii Alexander P. , Il’yushin Mikhail A. Alekseevich , Vozniakovskii Alexey A. , Shugalei Irina , Savenkov Georgy G.
Published: November 2023

Carbonization of a biopolymer (lignin) in self-propagating high-temperature synthesis (SHS) led to the production of 2D graphene structures. With the help of modern analytical methods (Raman spectroscopy, X-ray diffraction) and electron microscopy, the resulting product was confirmed to have a few-layer 2D graphene structure. The predicted photovoltaic properties of the resulting few-layer graphene were implemented for laser ignition of a model pyrotechnic composition based on porous silicon. A phenomenological model of the formation mechanism of 2D graphene structures under the conditions of the SHS process is proposed.
LGR5+ Intestinal Stem Cells Display Sex Dependent Radiosensitivity
Authors: Zitter Ryan C. , Chugh Rishi Man , Bhanja Payel , Saha Subhrajit
Published: November 2023

Radiosensitivity, the susceptibility of cells to ionizing radiation, plays a critical role in understanding the effects of radiation therapy and exposure on tissue health and regeneration. Identifying characteristics that predict how a patient may respond to radiotherapy enables clinicians to maximize the therapeutic window. Limited clinical data suggested a difference in male and female radiotherapy outcomes. Radiotherapy for gastrointestinal malignancy is still a challenge due to intestinal sensitivity to radiation toxicity. In this manuscript we demonstrated sex specific differences in intestinal epithelial radiosensitivity. In mice model of abdominal irradiation, we observed significant increase in oxidative stress and injury in male compared to female. Lgr5+ve intestinal stem cells from male mice showed higher sensitivity to radiation induced toxicity. However, sex specific differences in intestinal radiosensitivity are not dependent on sex hormone as we demonstrated similar sex specific radiosensitivity differences in pediatric mice. In ex-vivo study we found that human patient derived intestinal organoid (PID) derived from male showed higher sensitivity to irradiation compared to female as evident from loss of budding crypt, organoid size, and membrane integrity. Transcriptomic analysis of human Lgr5+ intestinal stem cells suggested radiation induced upregulation of mitochondrial oxidative metabolism in male compared to female possible mechanism for radiosensitivity differences.
Influence of Low-Pressure Plasma Treatments on the Lap-Shear Strength of Laser Joined AISI 304 Hybrids with Polypropylene and Polyamide 6.6
Authors: Tillmann Wolfgang , Wojarski Lukas , Hopmann Christian , Fatherazi Patricia , Timmer Christian
Published: November 2023

This paper investigates if the polar groups induced by a plasma treatment can increase the lap shear strength of laser joined metal and plastic hybrids. Optimal laser joining parameters for cold-rolled AISI304 – Polyamide 6.6 and sandblasted AISI304 - Polypropylene hybrids are developed. The OWRK-method was utilized to identify the change in surface free energy of a low-pressure plasma treatment. Plasma treated samples were joined and tested. The fractured surfaces were investigated via light microscopy and SEM. The arithmetic means of the plasma treated hybrids lap shear strength with polyamide 6.6 varied slightly but all measured values were within the range of the untreated samples. The lap shear strengths of the polypropylene hybrids were significantly reduced. This was attributed to an overaging and the development of low molecular weight oxidized materials which lead to a weak boundary layer. No correlation between surface free energy and the lap shear strength could be found.
Assessment of the Physical Activity of Children with Asthma Bronchiale
Authors: Balatoni Ildikó , Kiss Tímea , Balla György , Papp Ágnes , Csernoch László
Published: November 2023

Physical activity is especially important of children's everyday life with chronic disease. The aim of the study was to show whether asthma is a barrier to physical activity in our society. The correlation between the severity of the disease, body mass index, and physical activity were analyzed, and, parents' opinion whether children should participate in active sports was assessed. Physical activity of children with asthma was analyzed by questionnaires and activity-measuring armbands. 93 parents and their children were involved in the survey, while 20 children were wearing the armband. The age of children was 12.6±3.5 years (mean±SD), 69.9% were boys, 30.1% were girls. 93.4% of the respondents participated in physical education program and 56.5% also attended sporting activities on a regular basis. 61.2% of the children had mild, 37.6% moderate, and 1.2% severe asthma. 6.5% of the respondents stated that their illness had been consistently or frequently limiting the performance concerning their school or home duties over the past 4 weeks. Twelve percent of parents felt that physical activity was not appropriate in the context of this disease. We conclude, that fear of the consequences of physical activity depends largely on education which should involve their parents, teachers and coaches.
Relationship Between Perception of Anxiety Symptoms and Quality of Life of Caregivers of Children with Autism Spectrum Disorder in a Reference Center in Amazon
Authors: Da Silva Rayanne Vieira , Gomes Daniela Lopes
Published: November 2023

The relationship between perception of anxiety and quality of life in caregivers of children with autism was verified. To verify quality of life, the Short Form Healthy Survey Item was used; perception of anxiety was assessed using the Beck Anxiety Inventory. 80 caregivers of children with autism participated, with 68.7% of caregivers being mothers. Of the total number of caregivers, 68.8% had a severe level of anxiety. Regarding quality of life, they demonstrated greater impairment in Limitation due to physical aspects, Limitation due to emotional aspects, Vitality and Pain. Caregivers with severe anxiety levels had worse quality of life in the domains of pain (p = 0.012), social aspects (p =< 0.001), limitation due to emotional aspects (p = 0.001) and mental health (p =< 0.001). However, in the functional capacity domain, caregivers with a moderate level of anxiety had a better physical capacity score (p = 0.001). There was a negative correlation between the general anxiety score and the general physical (p = 0.029) and general emotional component of quality of life (p =< 0.001). It was found that caregivers of children with ASD present losses related to psychological factors, quality of life and the lack of social support.
Insecurity and it's Impact on Socio-Economic Development in Oyo State: A Study of Ibarapa North Local Government
Authors: Oluwakemi  Mary Alo
Published: November 2023

The existence of insecurity in a state necessitates immediate government attention and action as it poses a risk to human life and property and impedes socio-economic development. The study aims to evaluate insecurity and its impact on socio-economic development in Oyo state. It will also determine the major causes of insecurity problems and offer data that can help develop effective security strategies and policies. The study population consisted of residents who were randomly selected from the Ibarapa North Local Government Area of Oyo State, Nigeria. The descriptive survey method was adopted and analyzed with the Chi-square technique. According to this research, there is a negative correlation between insecurity and the state's socio-economic development. The study recommends good governance and inclusive government policies to curb insecurity and ensure the state's socio-economic development.
Exploring Seaweed and Glycine Betaine Biostimulants for Enhanced Phenolic Content, Antioxidant Properties and Gene Expression of Vitis vinifera cv. ‘Touriga Franca’ berries
Authors: Monteiro Eliana , De Lorenzis Gabriella , Ricciardi Valentina , Baltazar Miguel , Pereira Sandra , Correia Sofia , Ferreira Helena , Alves Fernando , Cortez Isabel , Gonçalves Berta , Castro Isaura
Published: November 2023

Climate change will pose a challenge for the winemaking sector worldwide, bringing progressively drier and warmer conditions and increasing the frequency and intensity of weather extremes. The short-term adaptation strategy of applying biostimulants through foliar application serves as a crucial measure in mitigating the detrimental effects of environmental stresses on grapevine yield and berry quality. The aim of this study was to evaluate the effect of foliar application of a seaweed based biostimulant (A. nodosum – ANE) and glycine betaine (GB) on berry quality, bioactive compounds, antioxidant activity, and elucidated their action on the secondary metabolism. A trial was installed in a commercial vineyard (cv. ‘Touriga Franca’) in the Cima Corgo (Upper Corgo) sub-region of the Douro Demarcated Region. A total of four foliar sprayings were performed during the growing season: at flowering, pea size, bunch closer, and veraison. There was a positive effect of GB in the berry quality traits. Both ANE and GB increased the synthesis of anthocyanins and other phenolics in berries and influenced the expression of genes related to the synthesis and transport of anthocyanins (CHS, F3H, UFGT, MATE1 and GST). So, they have the potential to act as elicitors of secondary metabolism, leading to improved grape quality, but also sets the foundation for sustainable agricultural practices in the long run.
Assessment of Quercetin Antiemetic Properties: In Vivo and In Silico Investigations on Receptor Binding Affinity and Synergistic Effects
Authors: Chowdhury Raihan , Bhuia Md. Shimul , Rakib Asraful Islam , Hasan Md. Rubel , Coutinho Henrique Douglas Melo , Araújo Isaac Moura , De Menezes Irwin Alencar , Islam Muhammad Torequl
Published: November 2023

Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has demonstrated a diverse range of biological activities. The primary objective of the present study is to assess the potential antiemetic properties of QUA using an in vivo and in silico approach. In this experiment, emesis was induced in 4-day-old chicks by orally administering copper sulfate pentahydrate (CuSO4.5H2O) at a dose of 50 mg/kg (orally). Domperidone (6 mg/kg), ondansetron (5 mg/kg), and hyoscine (21 mg/kg) were treated as positive controls (PCs), and distilled water was employed as a negative control (NC). QUA was administered orally at two distinct doses (25 and 50 mg/kg). Additionally, QUA (50 mg/kg) and PCs were administered separately or in combination to assess their antagonistic or synergistic effects on the chicks. The binding affinity of QUA and referral ligands towards 5HT3, D2, D3, and M1–M5 receptors was estimated, and ligand-receptor interactions were visualized through various computational tools. In vivo findings indicate that QUA (25 and 50 mg/kg) has a significant effect on reducing the number of retches (16.50 ± 4.65 and 10.00 ± 4.19 times) and increasing the chick latency period (59.25 ± 4.75 and 94.25 ± 4.01 seconds), respectively. Additionally, QUA (50 mg/kg) in combination with domperidone and ondansetron exhibited superior antiemetic effects, reducing the number of retches and increasing the onset of emesis-inducing time. Furthermore, it is worth noting that QUA demonstrated the strongest binding affinity towards the D2 receptor with a value of -9.7 kcal/mol through the formation of hydrogen and hydrophobic bonds. In summary, the study found that QUA exhibited antiemetic activity in chicks, potentially by interacting with the D2 receptor pathway.
Hepatocellular Carcinoma Mimicking Focal Nodular Hyperplasia
Authors: Gröger Lisa-Katharina , Hahn Felix , Straub Beate Katharina , Bartsch Fabian , Lang Hauke
Published: November 2023

Backround: FNH is a common benign liver lesion, mostly solitary, and with no evidence of malignant transformation over time. The diagnosis can usually be made by imaging modalities with distinct features in MRI- and CT-scans. Case series: We present a case series of three patients with solitary liver tumors which were highly suspicious to be large FNH, based on radiological features. The patients were sent to our center for second opinion and probable treatment. Indication for resection was given because of nonconclusive radiologic imaging in the first, substantial growth progression in the second and elevated AFP in the third case. Histology revealed well to poor differentiated HCCs. Discussion: FNH tends to show a distinct pattern in imaging modalities, but HCC can mimic FNH. The MRI-scan using hepatotropic contrast agent is the most sensitive imaging modality to diagnose FNH. AFP is usually not elevated in FNH. Asymptomatic FNH does not require surgery but a reliable diagnosis is crucial. In case of an uncertain diagnosis surgery should be offered to patients. Conclusion: In cases with a progression in size, an elevated level of AFP should be suspicious. A second opinion at a center for hepato-biliary surgery with HCC/FNH-experienced radiologists and surgeons is reasonable. Generally, an over-therapy via surgery should be avoided and follow-ups of a newly diagnosed FNH including measurement of AFP are advisable to detect alterations.
Assessing Wetland Ecosystem Services in a Biosphere Reserve in South Africa Through Citizen Science
Authors: Musetsho Khangwelo , Chitakira Munyaradzi
Published: November 2023

Wetland ecosystems provide valuable services to human beings, but they are also among the most threatened ecosystems in the world (1). Sixteen ecosystem services are identified through the South African Water Research Commission's Wet-Health Tool (2). This study sought to establish which of these ecosystem services are highly ranked/rated by the community members living in the Soutpansberg area in South Africa. This area is a strategic water source/watershed. The area is rich in biodiversity and is also experiencing competing administrative jurisdictions: the local traditional leadership and the municipal council. This study also sought to determine the influence of age, education status, employment status, and family income, among other demographic factors, on how people view the importance of services derived from wetlands. It also sought to establish whether people in urban settings view the ecosys-tem services obtained from wetlands similarly to people in rural settings. A literature review was conducted to understand the wetland ecosystem services and how communities benefit from these services. A close-ended questionnaire was used to collect data for the current study, which was circulated among the villagers around the wetlands, particularly those living close to the wetlands. One hundred and sixteen responses from the study were recorded. Food for livestock was ranked the greatest benefit or service derived from the wetlands rated by 82% of the participants, followed by the provision of cultivated foods at 60%, provision of water for human use at 58%, provision of harvestable resources at 42% and erosion control at 38% completes the top 5 ranked ecosystem services in the area. The study concluded that the participants living in rural areas had greater awareness of wetlands' ecosystem services than their urban counterparts.
Dermatophyte Infections Worldwide: Increase in Incidence and Associated Antifungal Resistance
Authors: Kruithoff Caroline , Gamal Ahmed , McCormick Thomas S. , Ghannoum Mahmoud A.
Published: November 2023

The increase in incidence of superficial fungal infections combined with the emergence of antifungal resistance represents both a global health challenge and a considerable economic burden. Recently, dermatophytes, the main culprit causing superficial fungal infections, have started to exhibit antifungal resistance. This can be observed in some of the most common species such as Trichophyton rubrum and Trichophyton mentagrophytes. Importantly, the new subspecies, known as Trichophyton indotineae, has been reported to show high resistance to terbinafine, a first-line treatment for dermatophyte infections. Compounding these issues is the realization that diagnosing the causative infectious agents requires using molecular analysis that goes beyond the conventional macroscopic and microscopic methods. These findings emphasize the importance of conducting antifungal susceptibility testing to select the appropriate antifungal necessary for successful treatment. Implementing these changes may improve clinical practices that combat resistant dermatophyte infections.
Carvacrol Microemulsion vs Nanoemulsion as Novel Pork Minced Meat Active Coatings
Authors: Zaharioudakis Konstantinos , Kollia Eleni , Leontiou Areti Α. , Moschovas Dimitrios , Karydis-Messinis Andreas , Avgeropoulos Apostolos , Zafeiropoulos Nikolaos E. , Ragkava Efthymia , Kehayias George , Proestos Charalampos , Salmas Constantinos E. , Giannakas Aris E.
Published: November 2023

Carvacrol is well-documented for its antibacterial and antioxidant effects. However, its high volatility has directed researchers towards nanoencapsulation technology according to bioeconomy and sustainability trends. This study examined and compared carvacrol microemulsion (MC), carvacrol microemulsion busted with chitosan (MMC) and carvacrol nanoemulsions as active coatings on extending minced pork meat shelf-life at 4±1 oC for 9 days, focusing on microbiological, physiochemical, and sensory characteristics. The research involved pre-characterizing droplet sizes, evaluating antioxidant, and determining antibacterial efficacy. The results demonstrated that NC with a 21 nm droplet size exhibited the highest antioxidant and antibacterial activity. All coatings succeed to extend the preservation of fresh minced pork meat in comparison to free carvacrol sample (FC). NC coating showed the highest extension of minced pork meat preservation and maintained meat freshness for 9 days, with a lower TBARs of 0.736 mg MDA/Kg, and effectively reduced mesophilic, lactic acid, and psychrotrophic bacterial counts more significantly 1.2, 2, and 1.3 log respectively as compared to FC. Sensory assessments confirmed the acceptability of NC and MCC coatings. Overall, the carvacrol based nanoemulsion can be considered as novel antioxidant and antimicrobial active coating due to its demonstrated higher efficacy in all the examined tests performed.
Mapping Corporate Social Responsibility in Family Firms: A Bibliometric Review Across Countries
Authors: Citterio Alberto , Locatelli Rossella , Uselli Andrea
Published: November 2023

The field of CSR has witnessed considerable growth and established itself as a significant subject in family business literature. However, despite previous reviews exploring this topic from various angles, there remains a crucial gap in understanding the influence of diverse regulatory frameworks and cultural values on the development of literature production and research streams across different regions. This gap holds particular significance for comprehending the latest advancements in this dynamic field, particularly in emerging economies, where cultural norms play a substantial role in shaping the relationship between family firms and CSR. To bridge this gap, this paper conducts a comprehensive review of empirical studies focusing on sustainability in family firms. These studies are organized based on the country of study, and our review encompasses 232 articles published between 1996 and 2023. Utilizing bibliometric software, we systematically group these articles into three distinct clusters: North American studies, European studies, and Asian studies, adhering strictly to our inclusion criteria.
The Candida Covid Connection: Preexisting Candida Overgrowth and Gut Dysbiosis Drives Long Covid
Authors: Chambers Patrick
Published: November 2023

Long Covid has become a blight, its economic consequences overwhelming. But Long Covid (LC) may represent persistent Covid-19 in those with preexisting Candida overgrowth (CO). The features shared by both are striking. LC may be a growing subset of CO. The altered tryptophan metabolism encountered in LC is driven by IFN-γ in reaction to CO. Females are robust producers of IFN-γ, yet estrogen promotes CO.The consequent decline in serotonin and melatonin triggers the mood swings and sleeplessness respectively in LC. The low serotonin, the primary messenger in the gut brain axis, creates autonomic dysfunction. The CO induced gut dysbiosis and leaky gut initiate an autoimmune path. TNFα seen in both LC and this opportunistic yeast is at the center of the cytokine triad that leads to neurodegeneration. The Western diet, high in carbohydrates, alcohol, and glutamate, is exploited by this commensal turned parasite. Residual SARS CoV2 and Candida generate abundant ROS, inducing mitochondrial dysfunction. Alcohol tastes different for many with LC, because acetaldehyde requires functioning hepatic mitochondria. This article delves into the complex physiology and biochemistry that drive the symptoms of this conspicuous connection. Recent research has revealed innovative approaches that might address this global scourge, including D-mannose for the immune dysfunction and butyrate for the gut dysbiosis created by and seen in both LC and intestinal Candidiasis.
Retinoid Therapy for Neuroblastoma: Historical Overview, Regulatory Challenges, and Prospects
Authors: Makimoto Atsushi , Fujisaki Hiroyuki , Matsumoto Kimikazu , Takahashi Yoshiyuki , Cho Yuko , Morikawa Yoshihiko , Yuza Yuki , Iehara Tomoko , Tajiri Tatsuro
Published: November 2023

Retinoids are vitamin A derivatives and include trans-retinoic acid, isotretinoin, tamibarotene, and bexarotene, all of which are currently available for clinical use. The clinical development of retinoid therapy for neuroblastoma has a history spanning more than four decades. The most promising agent is isotretinoin, which can contribute to improving event-free survival in patients with high-risk neuroblastoma by approximately 10 % when administered over six months as maintenance therapy. Although isotretinoin is regarded as an essential component in the standard clinical management of high-risk neuroblastoma, its use for this purpose in the US and EU is off-label. To promote isotretinoin use in Japan as a treatment for neuroblastoma, our clinical research team is planning to launch an investigator-initiated, registration-directed clinical trial. The present review article discusses the basic science behind retinoid therapy, pre-clinical / clinical evidence on neuroblastoma, the concept of the proposed clinical trial, and prospects for this therapy.