bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovation Overview of Nanoparticle-Based Dermatological Products: A Patent Study
Authors: da Costa Lucas A.G. , de Souza Myla L. , de Sousa André Luiz M.D. , Silva Emerson de O. , da Silva Rosali M.F. , Rolim Larissa A. , Rolim-Neto Pedro J.
Published: February 2020

Background:

The health area in its most diverse fields has progressively incorporated nanotechnology
into its products, such as in dermatology. In this sector, nanoparticles are one of the strategies
that allow improvements, both in terms of value-added, as well as the efficacy, safety and stability
of products for cosmetic or therapeutic purposes.

Objective:

To understand the scenario of development and innovation of dermatological products with
nanoparticles, through a patent prospection, evaluating the annual evolution, the main technology investors
countries, the profile of the depositors, besides the uses and purposes of the products.

Methods:

The Espacenet® database was used for consultation, using the search term "nanoparticle and
skin". A total of 285 patents were found, of which 208 were available and 89 were based on the scope.

Results:

There was a progressive evolution in the number of patents after the year 2000, with South
Korea, the United States, China and Japan as the main depositor countries. Private companies and Education
and Research Institutions were the entities with the largest amount of deposits. The cosmetic
purpose was the predominant use compared to the therapeutic one. The most prominent nanoparticles
were polymeric, metallic and lipid, while the therapeutic area presented a larger number of the functionalized
ones.

Conclusion:

The market for dermatological products has been innovating and growing over the years
through the use of nanoparticles, evidencing a prominent development of nanotechnology-based cosmetics.
Countries investing in nanotechnology and major developers of innovative products are highlighted
in this scenario.
Efektivitas small sided games dan interval training terhadap peningkatan daya tahan aerobik pada pemain sepakbola U-17
Authors: Arianto Andi Tri , Setyawan Caly
Published: February 2020

Penelitian ini bertujuan untuk membandingkan pengaruh antara latihan small sided games (SSG) dan interval training (IT) terhadap daya tahan aerobik pemain sepakbola under-17. Sebanyak 24 pemain sepakbola U-17 yang dibagi menjadi 2 grup: grup SSG (n = 12) dan grup IT (n = 12) mengikuti program latihan selama 6 minggu. Instrumen penelitian yang digunakan adalah Yo-Yo Intermitten Recovery Test. ANAVA dua jalur digunakan untuk proses analisis data. Pemain dari kedua grup menunjukkan peningkatan yang sama pada daya tahan aerobik selama periodesasi latihan 6 minggu. Hasil ini menunjukkan bahwa SSG dan IT sama efektif dalam meningkatkan daya tahan aerobik pada pemain sepakbola U-17 (p 0.05). Effect of Small Sided Games and Interval Training on Aerobic Endurance of U-17 Soccer Players AbstractThis study aims to compare the effect of small sided games and interval training on the aerobic endurance of U-17 soccer players. 24 soccer players under 17 attended a 6-week training program divided into 2 groups: SSG group (n = 12) and IT group (n = 12). The research instrument used was Yo-Yo Intermitten Recovery Test. Two-way ANOVA is used for data analysis. Players from both groups showed a similar increase in aerobic endurance during the 6-week training period. These results indicate that SSG and IT are equally effective in developing the aerobic endurance in U-17 soccer players (p 0.05).
PENGARUH INDEPENDENSI, AKUNTABILITAS, DAN OBJEKTIVITAS TERHADAP KUALITAS AUDIT
Authors: Laksita Arin Dea , Sukirno Sukirno
Published: February 2020

Abstrak : Pengaruh Independensi, Akuntabilitas, Dan Objektivitas Terhadap Kualitas Audit. Penelitian ini bertujuan untuk mengetahui: (1)  pengaruh Independensi terhadap Kualitas Audit, (2) pengaruh Akuntabilitas terhadap Kualitas Audit, (3) pengaruh Objektivitas terhadap Kualitas Audit pada, (4) pengaruh Independensi, Akuntabilitas dan Objektivitas terhadap Kualitas Audit. Responden dalam penelitian ini adalah 41 auditor internal yang bekerja pada Inspektorat Provinsi Daerah Istimewa Yogyakarta. Teknik analisis data yang digunakan adalah analisis regresi linear sederhana, regresi linear berganda. Hasil penelitian ini menunjukkan bahwa (1) Terdapat pengaruh positif Independensi terhadap Kualitas Audit, (2) Terdapat pengaruh positif Akuntabilitas terhadap Kualitas Audit, (3) Terdapat pengaruh positif Objektivitas terhadap Kualitas Audit, (4) Terdapat pengaruh positif Independensi, Akuntabilitas, dan Objektivitas terhadap Kualitas Audit. Kata kunci: Independensi, Akuntabilitas, Objektivitas, Kualitas Audit.
Conceptualizing Usability for the eHealth Context: Content Analysis of Usability Problems of eHealth Applications (Preprint)
Authors: Broekhuis Marijke , van Velsen Lex , Peute Linda , Halim Meilani , Hermens Hermie
Published: February 2020

BACKGROUND

Usability tests can be either formative (where the aim is to detect usability problems) or summative (where the aim is to benchmark usability). There are ample formative methods that consider user characteristics and contexts (ie, cognitive walkthroughs, interviews, and verbal protocols). This is especially valuable for eHealth applications, as health conditions can influence user-system interactions. However, most summative usability tests do not consider eHealth-specific factors that could potentially affect the usability of a system. One of the reasons for this is the lack of fine-grained frameworks or models of usability factors that are unique to the eHealth domain.

OBJECTIVE

In this study, we aim to develop an ontology of usability problems, specifically for eHealth applications, with patients as primary end users.

METHODS

We analyzed 8 data sets containing the results of 8 formative usability tests for eHealth applications. These data sets contained 400 usability problems that could be used for analysis. Both inductive and deductive coding were used to create an ontology from 6 data sets, and 2 data sets were used to validate the framework by assessing the intercoder agreement.

RESULTS

We identified 8 main categories of usability factors, including basic system performance, task-technology fit, accessibility, interface design, navigation and structure, information and terminology, guidance and support, and satisfaction. These 8 categories contained a total of 21 factors: 14 general usability factors and 7 eHealth-specific factors. Cohen κ was calculated for 2 data sets on both the category and factor levels, and all Cohen κ values were between 0.62 and 0.67, which is acceptable. Descriptive analysis revealed that approximately 69.5% (278/400) of the usability problems can be considered as general usability factors and 30.5% (122/400) as eHealth-specific usability factors.

CONCLUSIONS

Our ontology provides a detailed overview of the usability factors for eHealth applications. Current usability benchmarking instruments include only a subset of the factors that emerged from our study and are therefore not fully suited for summative evaluations of eHealth applications. Our findings support the development of new usability benchmarking tools for the eHealth domain.
Developing a Theory-Driven Serious Game to Promote Prescription Opioid Safety Among Adolescents: Mixed Methods Study (Preprint)
Authors: Abraham Olufunmilola , Thakur Tanvee , Brown Randall
Published: February 2020

BACKGROUND

Adolescents in North America are severely affected by the opioid crisis, yet there are limited educational resources for educating teens about prescription opioid safety and misuse. Empirical literature lacks evidence regarding teen education about prescription opioid safety through serious games and lacks conceptual models and frameworks to guide the process of game development for this purpose.

OBJECTIVE

This study aims to conceptualize and design a serious game prototype to teach teens about prescription opioid safety and propose a conceptual framework for developing a serious game to educate youth about safe and responsible use of prescription opioids.

METHODS

The initial steps of the project comprised of the formulation of an integrated conceptual framework that included factors from health behavior models and game development models. This was followed by the formal process of serious game development, which resulted in a game prototype. The assessment of the game prototype was done through group discussions, individual interviews, and questionnaires with adolescents following gameplay. Field notes were used to keep track of the responses from the group discussions. Content and thematic analyses were used to analyze field notes and responses to the open-ended questionnaire, which were then used to refine the game prototype.

RESULTS

A total of 10 playtests with over 319 adolescents and emerging young adults (AYAs) in community settings such as middle schools, high schools, and colleges were conducted by the project team between March and June 2019. The AYAs provided feedback on the initial game prototype using questionnaires administered through Qualtrics or in-person on paper. Preliminary feedback suggested that the teens found the game objectives, outcomes, and design appealing. Overall, the game was perceived as realistic, and learning outcomes seemed achievable. Suggestions for improvement included the need for additional direction on gameplay, clearer instructions, concise dialog, and reduced technical problems in the gameplay.

CONCLUSIONS

We propose a conceptual framework for developing a serious game prototype to educate youth about prescription opioid safety. The project used a theory-driven conceptual framework for the development of a serious game targeting the prevention of adolescent opioid misuse and garnered preliminary feedback on the game to improve the quality of gameplay and the prototype. Feedback through informal assessments in community settings suggests that the youth and their families are interested in a game-based approach to learn about prescription opioid safety in homes and schools. The next steps include modifications to the game prototype based on feedback from the community, integration of learning analytics to track the in-game behaviors of players, and formal testing of the final prototype.
Virtual Reality Meditation Among Youth Experiencing Homelessness: Pilot Randomized Controlled Trial of Feasibility (Preprint)
Authors: Chavez Laura Johnson , Kelleher Kelly , Slesnick Natasha , Holowacz Eugene , Luthy Ellison , Moore Laura , Ford Jodi
Published: February 2020

BACKGROUND

Homelessness among youth is devastating, with high rates of substance use disorders and mental health comorbidity. Mindfulness-based interventions that include meditation and mindfulness skills training reduce stress and symptoms of anxiety or depression. However, engaging high-risk youth in interventions is challenging. Virtual reality is a more flexible platform for delivering meditation and may be appealing to youth.

OBJECTIVE

The study objectives were to evaluate the feasibility of delivering virtual reality meditation and of collecting outcome measures, including anxiety and physiologic stress.

METHODS

A sample of 30 youth experiencing homelessness was enrolled in the study. Youth were randomized to receive 10 minutes of one of three interventions: (1) virtual reality meditation, (2) audio meditation (through a web-based platform), or (3) virtual reality imagery of historical pictures and text. Subjects who consented to the study attended two research visits. The first visit collected survey measures of demographics, mental health, and substance use, and oriented subjects to the intervention platforms. The second visit (1-3 days later) delivered the intervention and collected pre and post outcome measures of anxiety and physiologic stress (salivary cortisol). Changes in anxiety and cortisol at the second visit were compared across groups using a linear regression model in which the primary analysis compared virtual reality meditation to audio meditation and secondary analyses compared virtual reality meditation to virtual reality imagery.

RESULTS

Anxiety scores decreased in all groups, with a larger reduction among the virtual reality meditation group (difference=10.8) compared to the web-based meditation or virtual reality images groups (difference=5.8 and 5.0, respectively). After controlling for baseline values, there were no significant group differences in changes in anxiety scores or cortisol levels. In comparing virtual reality meditation and audio meditation, the effect size for anxiety was moderate (Cohen d=0.58) while the effect size for cortisol was small (Cohen d=0.08).

CONCLUSIONS

Preliminary results suggest that virtual reality meditation has a moderate benefit for anxiety but not physiologic stress. Future research is needed to confirm these results in a larger sample and to investigate whether the effects are sustained or increase with repeated use of virtual reality mediation. Virtual reality meditation appears feasible to deliver among homeless youth and merits further study.

CLINICALTRIAL

ClinicalTrials.gov NCT04004520; https://clinicaltrials.gov/ct2/show/NCT04004520
Studi Farmakoepidemiologi Vitamin Penambah Darah pada Ibu Hamil di Kecamatan Jatinangor
Authors: Amanah Irma Rismayanti , Amanah Irma Rismayanti
Published: February 2020

Introduction: The prevalence of iron deficiency anemia in pregnant women in the world according to WHO ranges from 35-37%, similarly found in pregnant women in Indonesia, Riskesdas in 2013 reported a prevalence of 37.1%. Although the treatment of iron deficiency anemia for pregnant women has been entered into ANC treatment, the prevalence has not given the expected thing. However, in Sumedang District, the prevalence of anemia in pregnant women in 2016 lower, 9.69%, pharmacoepidemiological data related to the use of blood boosting vitamins in Jatinangor is still limited. this research was conducted in Jatinangor as target area of Universitas Padjadjaran.Objective: To know the blood Enhancer supplement consumption practices on pregnant women in Jatinangor.Methods: A cross-sectional study was carried out in July-August 2018 with pregnant women in Jatinangor, based on the formula large sample descriptive, sampling conducted in 12 villages and subjects were selected consecutively. Data analysis was carried out descriptively interview data using a closed questionnaire.Results: within research recorded 532 pregnant woman, 110 pregnant women are eligible to participate. It was found 96 pregnant women taking blood boosting vitamins, 69 Taking folicacid, 27 taking irontablets, 15 consuming B12, 2 consuming B6. It was found who did not take vitamins, 14 pregnant women for several reasons, 8 people felt healthy, 3 people felt the complaints were mild so it does not require vitamins, 4 others were afraid of the side effects.Conclusion: Most of the respondents already know how to consume suplments
Gambaran Aktivitas Perawat tentang Penatalaksanaan Masalah Pk: Peningkatan Tekanan Intrakranial
Authors: Umam Khotibul , Susanto Joko
Published: February 2020

Latar Belakang: Standar Asuhan Keperawatan (SAK) dan standar prosedur operasional (SOP) merupakan pedoman bagi perawat dalam memberikan asuhan keperawatan yang bermutu. Saat ini RSUD dr. Soegiri Lamongan belum mempunyai SAK tentang pasien dengan peningkatan tekanan intrakranial, evaluasi SAK yang dijadwalkan pelaksanaanya setiap tahun saat ini tidak berjalan.Tujuan: Mengetahui gambaran aktivitas perawat pada penatalaksanaan masalah kolaborasi (PK): peningkatan TIK di RSUD dr. Soegiri LamonganMetode: Penelitian deskriptif observasional dilakukan terhadap 39 pasien PK: peningkatan TIK yang dirawat di ruang Dahlia 3 RSUD dr. Soegiri Lamongan. Pengamatan dilakukan selama 3 kali 24 jam perawatan dengan menggunakan lembar observasi berupa ceklist aktivitas perawat kemudian hasilnya dibuat proporsi. Penelitian dilakukan pada bulan November sampai dengan Desember 2018Hasil: Analisis data menunjukkan bahwa pelaksanaan aktivitas perawat pada penatalaksanaan masalah kolaborasi PK: peningkatan TIK terhadap 39 responden pasien dengan PK: peningkatan TIK terdapat 991 aktivitas yang seharusnya dilakukan (sesuai kondisi pasien), sebanyak 382 aktivitas (38,6%) dilakukan sesuai dengan standar, 456 aktivitasa (46%) dilakukan tetapi tidak sesuai dengan standar, dan sebanyak 153 aktivitas (15,4%) tidak dilakukan aktivitas oleh perawat. Terdapat 2 aktivitas yang tidak dilakukan sama sekali (100%) yaitu pemantauan urine output dan penghitungan balance cairan. Terdapat 1 aktivitas yang tidak dilakukan lebih dari 75% yaitu penghitungan tekanan rata-rata arteri (MAP)Kesimpulan: Secara umum pelaksanaan aktivitas perawat termasuk dalam kategori baik, akan tetapi kalau dilihat secara kuantitas pelaksanaan aktivitas perawat termasuk dalam kategori kurang. Masih ada aktivitas yang tidak dilakukan 100%, yaitu pemantauan urine output dan penghitungan balance cairan. Terdapat aktivitas yang tidak dilakukan lebih dari 75%, yaitu penghitungan MAP.
CAR-T therapy and historical trends in effectiveness and cost–effectiveness of oncology treatments
Authors: Baumgardner James R , Brauer Michelle S , Zhang Jie , Hao Yanni , Liu Zhimei , Lakdawalla Darius N
Published: February 2020

Aim:
This study examines how chimeric antigen receptor T-cell (CAR-T) therapy’s incremental effectiveness and cost–effectiveness profile fits into the recent history of anticancer treatments.
Materials & methods:
We conducted graphical and multivariable analyses using data from the Cost–Effectiveness Analysis Registry of the Tufts Medical Center and the Institute for Clinical and Economic Review’s analysis of CAR-T therapies. We collected additional information including the US FDA approval years for pharmacologic innovations.
Results:
CAR-T provided 5.03 (95% CI: 3.88–6.18) more incremental quality-adjusted life-years than the average pharmaceutical intervention and 4.61 (95% CI: 1.67–7.56) more than the average nonpharmaceutical intervention, while retaining similar cost–effectiveness. There was evidence of worsening cost–effectiveness by approval year for pharmaceutical interventions.
Limitations:
Analysis is limited to anticancer treatments studied in cost–utility analyses, estimated to cover approximately 60% of FDA-approved antineoplastic agents.
Conclusion:
CAR-T therapy breaks a pattern of stagnant efficacy growth in pharmaceutical innovation and demonstrates significantly greater incremental effectiveness and similar cost–effectiveness to prior innovations.
Nonindependence of patient data in the clinical practice research datalink: a case study in atrial fibrillation patients
Authors: Sammon Cormac J , Leahy Thomas P , Ramagopalan Sreeram
Published: February 2020

Aim:
The impact of different strategies to handle patients with data recorded under multiple Clinical Practice Research Datalink (CPRD) identifiers (IDs) is unknown.
Patients and methods:
Six approaches to handling patients appearing under multiple CPRD IDs were defined. The impact of the approaches was illustrated using a case study describing the clinical characteristics of a population of nonvalvular atrial fibrillation patients.
Results:
5.6% of patients had more than one CPRD ID. Across all six approaches implemented, no material difference in the characteristics of nonvalvular atrial fibrillation patients were observed.
Conclusion:
While strategies which longitudinally append patient registration periods under different CPRD IDs maintain independence while using all available data, their implementation had little impact on the results of our case study.
Diagnóstico sobre competencias en investigación de estudiantes de Enfermería
Authors: Alonso Trujillo Javier , Cuevas Guajardo Leticia , Alonso Ricardez Abraham
Published: February 2020

Introducción. Las competencias investigativas incluyen valores y actitudes, habilidades cognitivas y habilidades procedimentales. El docente debe ser facilitador del aprendizaje. Objetivo. Analizar las principales competencias en investigación cuantitativa que, durante seis foros de difusión científica, desarrollaron estudiantes de Enfermería, en una institución de educación superior en México. Metodología. Estudio observacional, transversal, prospectivo y analítico. Unidades de información; resúmenes integrados a las memorias de foros de investigación. Muestra. 198 resúmenes de trabajos de investigación incluidos en las memorias de los foros XVII a XXII. Resultados. La competencia para trabajar en equipo está bien desarrollada en los estudiantes, pues en la mayoría de los casos los equipos se integran por 3, 4 o 5 estudiantes. 47% de los trabajos sintetizaron bien su estudio. El 61.1% de los trabajos usó software especializado. El 68.7% con enfoque cuantitativo, 31.3% cualitativos, 89.9% sin intervención, 40.4% tamaños de muestra mayor a 30 unidades de estudio, 89.4% muestreos no probabilísticos, 20.2% aplicó pruebas de hipótesis, 15.7% interpretó correctamente el valor “p” y 88.9% fue coherente objetivo, resultados y conclusiones. Conclusiones. Predomina el trabajo en equipo, las habilidades cognitivas son deficientes y las habilidades procedimentales, relacionadas con la metodología y el manejo de software especializado, es apenas suficiente. Se observó una tendencia hacia el uso de diseños sencillos, sin intervenciones, con escases de procedimientos que permitan la inferencia estadística, omisión de pruebas de hipótesis e interpretaciones incorrectas de conceptos estadísticos importantes para el análisis de datos.
Servicio social foráneo: Vivencias de pasantes de enfermería en el cuidado obstétrico
Authors: Bernal Becerril Martha Lilia , Godínez Rodríguez María De los Ángeles
Published: February 2020

El servicio social universitario como actividad académica formativa, fortalece habilidades, conocimientos, actitudes y aptitudes desarrolladas en los estudios profesionales. Como lo señala Gadamer, el concepto “formativo” significa la cultura que posee una persona como resultado de su formación en los contenidos de la tradición de su entorno. Se refiere tanto al proceso por el que se adquiere la cultura como al patrimonio personal, es decir, al conjunto de sus experiencias de aprendizaje. Se trata de una actitud espiritual que procede del conocimiento y el sentimiento de toda la vida espiritual y ética y que fluye armónicamente en la sensibilidad y el carácter1. Así, la experiencia que representa el servicio social dejará en los egresados mayores y mejores destrezas y conocimientos que determinaran la práctica profesional; muestra ese arraigo que logra obtener el alumno o alumna en el cual con el paso del tiempo va existir una reconciliación con el conocimiento de sí mismo (que observa y siente que va adquiriendo nuevas habilidades) en el ser otro (al adaptarse a los fenómenos que se le van presentando).

El servicio social es un tiempo que implica experiencias personales positivas y negativas que determinan, en muchos casos, la evolución profesional rodeada de aciertos, errores, dudas y también satisfacciones, y si se realiza en comunidades con alta vulnerabilidad en la atención del cuidado a la salud materna puede ser de mayor complejidad. Objetivo: explorar la vivencia de los pasantes de servicio social foráneo en el cuidado obstétrico. Método estudio cualitativo, con aproximación fenomenológica. La recolección de la información fue a través de entrevistas semiestructuradas a pasantes de licenciatura en enfermería y obstetricia que realizaron servicio social en estados de la República Mexicana como Hidalgo y Tlaxcala, dedicándose a la atención de la salud materna. Selección intencional de participantes hasta alcanzar saturación teórica de la información. El procesamiento de la información se realizó por medio de análisis temático. Resultados parciales del estudio  Significado del cuidado obstétrico en pasantes de enfermería. Categoría: Cuidado Integral de Enfermería en la Atención Obstétrica. Subcategorías: a) Cuidado integral: marcando la diferencia b) Confianza por el cuidado otorgado y c) Un antes y un después. Conclusión: el servicio social potencializa la formación profesional iniciada en las aulas, propicia satisfacción personal y profesional al ser reconocida la labor desempeñada en el cuidado integral y la contribución social para mantener mejores condiciones de la salud materna.
Estado cognitivo y funcionalidad para las actividades básicas en el adulto mayor institucionalizado
Authors: Flores Silva Alejandra Susana , Fierros Flores Ahtziri , Gallegos Novela Vanessa Edelmira , Magdaleno Ordaz Giselle , Velasco Rodríguez Raymundo , Pérez Hernández María Gicela
Published: February 2020

Introducción: El envejecimiento es un proceso fisiológico donde el organismo experimenta cambios de manera constante. Junto a este proceso se observa el deterioro cognitivo y disminución de la funcionalidad en las actividades básicas de la vida diaria (ABVD). Objetivo: Conocer la relación que existe entre el estado cognitivo y la funcionalidad para las actividades básicas de la vida diaria del adulto mayor (AM) institucionalizado. Método: Estudio transversal descriptivo, con participación de 32 adultos mayores de ambos sexos. Previo consentimiento informado, se aplicaron escalas de Mini-Mental de Folstein e Índice de Barthel. Para identificar asociación entre variables se utilizó correlación de Spearman y para identificar asociación entre  género se utilizó Chi-cuadrada. Un valor de P≤ 0.05 fue establecido para identificar diferencias significativas entre ambos grupos.          Resultados: 56.2% (n=18) fueron mujeres y 43.75% (n=14) hombres. Edad promedio fue 80.5 ± 8.97. El Índice de Barthel identificó que solamente 12.5% (n=4) eran independientes en tanto que 87.5% (n=28) presentaba algún grado de dependencia funcional. La escala de Folstein evidenció que 6.2% (n=2) eran normales y el resto (n=30) presentaba algun grado de deterioro cognitivo. No se evidenciaron diferencias significativas con base a género ni para funcionalidad (p=0.45) ni para deterioro cognitivo (p=0.85) respectivamente. La correlación de Spearman evidenció r = 0.66 y p = < 0.0001. Conclusión: Existe asociación del estado cognitivo con la funcionalidad para las ABVD en el AM institucionalizado, determinando que a mayor deterioro cognitivo mayor será su dependencia funcional; El género no tiene influencia sobre dicha asociación.

 
Proceso de enfermería con modelo bifocal aplicado a paciente con alteración hemodinámica
Authors: Barrera Magaña Luis Jonatan , Romero Ojeda Mario
Published: February 2020

Enfermería es una disciplina que necesita la aplicación del método científico, el cual se conjunta en el Proceso de Enfermería (PE), para la solución de problemas enfermeros. El PE consiste en un documento escrito que refleja el rol enfermero, que es estructurado, sistemático, dinámico y cíclico, centrado en la persona, orientado a resultados y basado en la evidencia. El objetivo en este trabajo fue aplicar un PE con modelo bifocal a paciente femenino del servicio de Unidad de cuidados intensivos adultos (UCIA) en el Instituto de Seguridad Social del Estado de México y Municipios (ISSEMYM) Tlalnepantla, con la finalidad de coadyuvar a su pronta recuperación y restablecimiento de salud. Se realizó un PE a paciente femenino el 31 de Octubre del 2017, bajo un modelo bifocal de Carpenito, que permite la conjunción del diagnóstico de Enfermería (empleando la taxonomía NANDA) y el problema interdependiente para resolver el problema de salud de la paciente. La elaboración del plan de cuidados fue la interrelación entre las taxonomías NOC (para encontrar resultados) y NIC (para encontrar intervenciones). Se concluye que el modelo bifocal en el PE permite en primer lugar la colaboración con el personal de salud y en segundo revertir de manera gradual el problema de salud de la paciente, favoreciendo su restablecimiento.
ATIVIDADE ALELOPÁTICA DE EXTRATO AQUOSO DE Eucalyptus grandis Hill ex Maiden SOBRE ALFACE (Lactuca sativa L.) e PICAO-PRETO (Bidens pilosa L.)
Authors: Espinosa Rafael Zorzenoni , Libório Flávia Helena de Moura , Da Silva Luciano Ivano , Zonetti Patricia da Costa , Mannigel Anny Rosi , Felipe Daniele Fernanda , Gonçalves-Zuliani Aline Maria Orbolato , Bido Graciene de Souza
Published: February 2020

Planta invasora de difícil controle, o picão-preto (Bidens pilosa L.) pode ser encontrado em quase todo o Brasil, inclusive nas áreas agrícolas ocupadas com espécies olerícolas, como a alface (Lactuca sativa L.). O controle das plantas invasoras tem sido realizado principalmente pelo uso de herbicidas, promovendo impacto ambiental e risco a saúde humana e animal. Assim, o objetivo deste trabalho foi avaliar o potencial alelopático do extrato aquoso de folhas secas de Eucalyptus grandis Hill ex Maiden sobre a germinação e o crescimento inicial de alface e picão-preto. Foram analisadas quatro concentrações do extrato aquoso (25, 50, 75 e 100%), além da testemunha (0%). O delineamento experimental foi inteiramente casualizado, com três repetições de cada tratamento, constituídas por 50 sementes de alface ou picão-preto distribuídas em gerbox e mantidas em câmara tipo B.O.D com fotoperíodo de 12h a 25ºC por 7 dias. Os resultados obtidos indicaram que Eucalyptus grandis Hill ex Maiden não apresentou potencial alelopático em relação às plântulas de picão-preto e a baixas concentrações pouco influenciou a germinação e o crescimento inicial de plântulas de alface.
PRÁTICA ESCOLAR E AVALIAÇÃO EXTERNA: OLHAR ATENTO ÀS RELAÇÕES QUE SE ESTABELECEM NO INTERIOR DA SALA DE AULA
Authors: Nazareth Henrique Dias Gomes de
Published: February 2020

O artigo apresenta resultados de investigação realizada em uma escola de ensino fundamental da rede municipal do Rio de Janeiro. A pesquisa aconteceu ao longo de um ano em uma turma de 1º ano do ensino fundamental e visou captar as implicações para as crianças, para a professora e cotidiano da escola advindas dos exames externos. Buscou-se um olhar atento às relações que se estabelecem no interior desta sala de aula, principalmente no que se refere aos impactos das determinações das políticas em curso. O estudo apontou que as ações regulatórias estabelecem pressões para modificar o que significa ser professor. Considerou também que no contexto do Rio de Janeiro, a avaliação em larga escala tem deixado de ser instrumento de acompanhamento global de redes de ensino e orientador de políticas públicas, mas passa a ser considerada capaz de avaliar a aprendizagem de alunos e o trabalho de professores, associada às políticas de responsabilização e bonificação, gerando distorções, tensões e conflitos para os estudantes, profissionais da escola e comprometendo as análises que deveriam ser geradas por processos de avaliação que tem por finalidade a reflexão e tomada de decisões acerca da possíveis mediações didáticas para que as aprendizagens se realizem.
Corpus eletrônico de Documentos Históricos do Sertão
Authors: Carneiro Zenaide De Oliveira Novais , Lacerda Mariana Fagundes de Oliveira
Published: February 2020

Resumo

Este trabalho apresenta o Banco CE-DOHS – Corpus Eletrônico de Documentos Históricos do Sertão, na sua primeira etapa, que abrange o período que vai de 1750 a 2000, caracterizado pelo multilinguismo localizado. O CE-DOHS é a versão eletrônica – com textos editados em linguagem xml – do banco DOHS, do projeto Vozes do Sertão em Dados: história, povos e formação do português brasileiro, com textos em edição semidiplomática, além de amostras orais. A edição eletrônica é feita, no âmbito do CE-DOHS, usando o eDictor, desenvolvido por Paixão de Sousa, Kepler e Faria (2010); trata-se de um editor de textos especialmente voltado ao trabalho filológico e à análise linguística automática. Finalizada a primeira etapa, no ano de 2018, o banco CE-DOHS tem mais de um milhão de palavras, colaborando, de maneira muito significativa, com o Projeto Nacional para a História do Português Brasileiro (PHPB), do qual é parceiro.

Palavras-chave: Português Brasileiro. Banco de Dados. Edições Eletrônicas.

 

Resumen

Este documento presenta el Banco EC-DOHS - Corpus de Documentación Electrónica de Sertão, en su primera etapa, que abarca el período de 1750 a 2000, caracterizado por el multilingüismo localizado. CE-DOHS es la versión electrónica, con textos editados en lenguaje XML, del banco DOHS, del proyecto Vozes do Sertão en Datos: historia, pueblos y formación del portugués brasileño, con textos en edición semidiplomática y muestras orales. La edición electrónica se realiza, en el marco de CE-DOHS, utilizando eDictor, desarrollado por Paixão de Sousa, Kepler y Faria (2010); Es un editor de texto enfocado especialmente en el trabajo filológico y el análisis lingüístico automático. Después de la primera fase, en 2018, el banco CE-DOHS tiene más de un millón de palabras, colaborando de manera muy significativa con el Proyecto Nacional de Historia del Portugués Brasileño (PHPB), del cual es socio.

Palabras clave: Portugués brasileño. Banco de datos. Ediciones electrónicas.
INTERCÂMBIO ACADÊMICO INTERNACIONAL EM ODONTOLOGIA: RELATO DE EXPERIÊNCIA
Authors: Daltro Borges Alves Lisia , Da Costa Hervânia Santana
Published: February 2020

O objetivo deste estudo foi relatar as atividades desenvolvidas e descrever as experiências vivenciadas por uma discente de Odontologia da Universidade Estadual de Feira de Santana, em programa de mobilidade acadêmica internacional, na Universidad del País Vasco, Bilbao – Espanha, de agosto de 2015 à julho de 2016. Neste período foi possível participar de um curso de espanhol, o que conferiu um maior domínio da língua estrangeira, e frequentar  aulas teóricas e práticas de Odontologia do programa acadêmico da Universidade del País Vasco, o que permitiu o contato com novas didáticas e tecnologias. Do mesmo modo, a discente pôde participar e apresentar trabalhos em eventos científicos, possibiitando o contato com pesquisadores internacionais. Realizouestágio no Hospital Universitário de Cruces, onde observou e vivênciou o funcionamento do Sistema Público de Saúde Vasco. A realização do intercâmbio e destas atividades ofereceram oportunidades para o aperfeiçoamento pessoal, profissional e técnico-científico da discente.
It’s All About Access!
Authors: Youssef Gretchen A.
Published: February 2020

Editor’s Note: This article is adapted from a speech Ms. Youssef delivered as President, Health Care & Education of the American Diabetes Association at its 79th Scientific Sessions in San Francisco, CA, on 8 June 2019. A webcast of the speech can be viewed on ADA’s DiabetesPro website at professional.diabetes.org/webcast/president-health-care-education-address%E2%80%94it%E2%80%99s-all-about-access.
Epidemiological Aspects of Clostridium Difficile Infection in the Southeast Region of Romania
Authors: Liliana Baroiu , Miruna Drăgănescu , Manuela Arbune , Alina Iancu , Caterina Dumitru , Anghel Lucreția , Mihaela Cudălbeanu , Magdalena Dumitru Irina , Sorin Rugină
Published: February 2020

Clostridium difficile infection (CDI) in Galati county is an very important public health problem, the number of cases per 100 outpatients being in the first 5, nationally. The percentage of community-associated infection in this county is higher than the national and european ones. We performed a prospective observational study on 720 patients admitted between 1.01.2017-31.12.2018 in the Clinical Hospital of Infectious Diseases „St. Cuv. Parascheva“ Galati and we analyzed comparative demographic data, risk factors, disease evolution and prognosis of a batch of 565 (78.47%) patients with healthcare facility associated infection, with a batch of 144 patients (20%) with community-associated infection. The identified type of Clostridium difficile was ribotype 027 in 93.61% of the toxigenic strains studied. The study showed that CDI predominantly affects women in urban areas. Patients with community source are younger, with less comorbidities, have episodes of illness with lower severity and better prognosis both in terms of CDI recurrence and post-CDI death. Patients with a nosocomial source are older, with multiple comorbidities, with greater exposure to antibiotic, proton pump inhibitor and recent abdominal surgery, have severe episodes of the disease and have a poorer prognosis than those with a community source.
On Dr. Stockmann’s Parrhesia: Ibsen’s An Enemy of the People in the Light of Foucault
Authors: Haj’jari Mohammad-Javad , Hooti Noorbakhsh
Published: February 2020

An honest intellectual dutifully standing with truth against lies and treacheries of his society is a parrhesiastic figure in Foucault’s terminology. Foucault takes parrhesia as the fearless and frank speech regarding the truth of something or a situation before truthmongering and public deception and he takes the parrhesiastic as the spokesperson for truth. In this light, Dr. Stockmann in Ibsen’s An Enemy of the People occupies a unique position within Ibsen’s political philosophy. Dutifully criticizing what the majority blindly take for granted from their liar leaders in the name of democracy, Dr. Stockmann fulfills the role of a parrhesiastic figure that stands against socio-political corruption. He enters a parrhesiastic game with both the majority and the officialdom to fulfill his democratic parrhesia as a truthful citizen before the duped community, while covertly preparing for his own philosophic parrhesia or self-care within the conformist community. However, his final failure lies in his confrontation with democracy itself, which wrongly gives the right of speaking even to the liars. This article thus aims at analyzing Ibsen’s play through a Foucauldian perspective regarding the concept of parrhesia and its relation to democracy. It is to reveal Ibsen’s satire on the fake ideology of democracy and highlight the necessity of humanity’s parrhesiastic self-care for the well-being of the self and the others.
Post-Crisis Household Savings Behavior in Romania
Authors: Anghel Dan-Gabriel , Străchinaru Adina-Ionela
Published: February 2020

The recent linear growth trend recorded by net savings in Romania is very intriguing. We thus study household savings behavior using Vector Autoregression and Vector Error Correction models on a sample of post-2007 monthly data. Contrary to common economic theory, we find that real interest rates do not influence the loan and savings behavior of Romanian households in our sample, despite their significant volatility and, even, negative recorded values. The results indicate a change in attitude and in risk perception of Romanian households in the aftermath of the financial crisis in 2008, in the way that has significantly decreased their preference for present consumption in favor of savings. Despite the significant increase in net savings, we also find that they have not significantly contributed to economic growth.
Recent Social Trends Among Romanian Twitter Users
Authors: Florea Alexandru-Răzvan
Published: February 2020

Online Social Networks have become a significant part of our quotidian life. In this paper, we aim to provide a proof of concept of how social media data can be effectively extracted, processed and analyzed with powerful open source tools like R. Moreover, we aim to build a reliable methodology for testing and validating social trends by using social media data. We used API routines to establish the connection between R and Twitter, Deep Learning Models to estimate the demographics of the users, Logistic Regression Models to estimate the predispositions of the users, and Propensity Score Matching to build comparable data sets. After analyzing the Romanian Twitter users, the results of our inquiry show that most of them are relatively young and the percentage of males is significantly higher than the percentage of females. Moreover, our results confirm that facial appearances play an essential role in the popularity of an individual.
Statistical applications of optimization methods and mathematical programming
Authors: Manea Daniela-Ioana , Țiţan Emilia , Șerban Radu R. , Mihai Mihaela
Published: February 2020

Optimization techniques perform an important role in different domains of statistic. Examples of parameter estimation of different distributions, correlation analysis (parametric and nonparametric), regression analysis, optimal allocation of resources in partial research, exploration of response surfaces, design of experiments, efficiency tests, reliability theory, survival analysis are the most known methods of statistical analysis in which we find optimization techniques.

The paper contains a synthetic presentation of the main statistical methods using classical optimization techniques, numerical optimization methods, linear and nonlinear programming, variational calculus techniques. Also, an example of applying the “simplex” algorithm in making a decision to invest an amount on the stock exchange, using a prediction model..
How do Romanian Youths Fare in Their Journey from School to Work?
Authors: Oţoiu Adrian , Țiţan Emilia
Published: February 2020

The paper attempts to present a comprehensive picture of the main characteristics of Romanian university-educated youths in their journey to employment. The persisting demographic decline and significant labor shortages point out to the importance of having an effective transition from school to work (as reflected in several Europe 2020 policy targets) so that youth and young adult cohorts are able to contribute to the Romanian economy to the full extent of their abilities. Analysis of the latest data available reveals that Romanian university graduates’ path to employment often involves a complete switch from study to work. Despite a lack of previous work experience, they enjoy high employment rates, relatively long job tenure that starts on, or shortly after, graduation, and have jobs that match their education. They also tend to be proactive in their job search and over 90% are not willing to change residence in order to start employment. Inactivity patterns that consider both work and education, and early leavers from education show significant fluctuations during the economic cycle. Results indicate the strong and weak areas with respect to labor market integration of youths and young adults, and can provide a starting point for policies to optimize their successful integration. It also points out to potential research areas to address key aspects of transitions from school to work that may clarify unsolved issues and guide effective policy interventions.
Smoking as a bad habit: a behavioral economics perspective
Authors: Ștefăneţ Mădălina-Elena , Grădinaru Simona , Coşer Alexandru , Stancu Stelian
Published: February 2020

Tobacco consumption is a problem of both health and economic interest nowadays. According to recent studies conducted by the European Commission approximate 700,000 deaths per year are caused by smoking. For this reason, the European Commission frequently conducts a survey in order to monitor the attitude towards tobacco addiction. Smoking addiction changes due to different factors such as budget, time or entourage. The evolution in time of these factors and the consumers’ preferences is studied using behavioral economics based on a small group of respondents. Through a survey, over 500 persons were asked to choose their preference for cigarettes characteristics. We employ correspondence analysis using combinations of age, type of cigarette, number of cigarettes smoked per day and nicotine concertation to see the type of responses the consumers’ have according to their habit. Moreover, we made a 5 persons selection from the initial group and we observed their behavior for 9 months period of time. The consumers were asked to classify a set of packages according to their preferences and we applied conjoint analysis in order to determine how or if the initial preferences change. Furthermore, we explain the changes in behavior by taking into account the nowadays global impetus towards a healthier lifestyle. The results provided allow to emphasize the role of a strong analysis for each single target consumer’s behavior as this is one of the main roles of Behavioral Economics.
The Importance of FDI on Stimulating Entrepreneurship – A Regional Study in the Case of Romania
Authors: Tigau Horia
Published: February 2020

The world economy has been developing at a very fast pace for the past few decades, growth which is commonly linked to the development of technology. Innovative ideas become successful when certain individuals decide to face the multiple risks that appear when transforming these ideas in to reality. The vast literature on entrepreneurship has shown that startups are important players in driving the economy on an ascending path. It is no surprise that highly developed countries, such as USA, Israel or Singapore have governmental programs which stimulate startup creation. More recently, the Romanian government has also joined in on spending money to offer entrepreneurs the chance to create successful businesses. Using spatial panel data on the 41 counties of Romania and the capital, Bucharest, on the period 2011-2016, this study highlights some significant dependencies between the survival of startups (for a period of 3 years) and other factors – both internal and external. The analysis shows that the aforementioned survival is clearly and positively impacted by Foreign Direct Investment, the share of fresh businesses in the total business environment and the number of immigrants with a permanent residence in the respective counties. Moreover, there are significant spatial effects occurring between neighboring counties. These results suggest that foreign investors could benefit from bringing their capital in Romania, as startups greatly contribute to the specialization of markets, and moreover, spillover effects present suggest that a smaller number of investment centers can be highly effective in their regions.
The Dynamical Assessment of Inflammatory Biomarkers in Predicting the Outcome of Septic Patients and the Response to Antimicrobial Therapy
Authors: Orfanu Alina , Aramă Victoria , Popescu Cristina , Tilişcan Cătălin , Streinu-Cercel Adrian , Aramă Ştefan Sorin
Published: February 2020

Aims

To evaluate the kinetics of inflammatory biomarkers in septic patients in order to identify the most reliable predictor of unfavorable outcome.

Methods

A prospective analysis of septic patients was performed. Median levels of neutrophil/lymphocyte count ratio, fibrinogen, C-reactive protein and procalcitonin were dynamically assessed and comparatively analyzed.

Results

Seventy-seven patients were included. Descendent kinetic patterns were registered for all biomarkers, except C-reactive protein. At 24 hours, neutrophil/lymphocyte count ratio significantly decreased in 42.85% of cases, procalcitonin in 37.33%, C-reactive protein in 16.12% and fibrinogen in 1.58% of cases. At 72 hours, procalcitonin decreased to one-half in 70% of cases and neutrophil/lymphocyte count ratio in 67.53% of cases.

Conclusions

Neutrophil/lymphocyte count ratio and procalcitonin significantly decreased in the first 72 hours, while C-reactive protein increased in the first 24 hours. The proportions of patients with major decrease of baseline values were higher for neutrophil/lymphocyte count ratio and procalcitonin.
Velocity profiles and turbulence intensities around side-by-side bridge piers under ice-covered flow condition
Authors: Namaee Mohammad Reza , Sui Jueyi
Published: February 2020

Recent studies have shown that the presence of ice cover leads to an intensified local scour pattern in the vicinity of bridge piers. To investigate the local scour pattern in the vicinity of bridge pier under ice-covered flow condition comparing to that under open channel flow condition, it is essential to examine flow field around bridge piers under different flow conditions. In order to do so, after creation of smooth and rough ice covers, three-dimensional timeaveraged velocity components around four pairs of bridge piers were measured using an Acoustic Doppler velocimetry (ADV). The ADV measured velocity profiles describe the difference between the velocity distributions in the vicinity of bridge piers under different covered conditions. Experimental results show that the vertical velocity distribution which represents the strength of downfall velocity is the greatest under rough covered condition which leads to a greater scour depth. Besides, results show that the turbulent intensity increases with pier size regardless of flow cover, which implies that larger scour depth occurs around piers with larger diameter.