bluuebunny/crossref_metadata_2025 huggingface dataset:
El comercio veneciano de material impreso y papelería con España: los pedidos de Josep Bro, librero de Girona, a la casa Remondini (1764-1775)
Authors: Antón Pelayo Javier
Published: September 2017

En la primera mitad del siglo XVIII los libreros españoles abastecieron sus tiendas con obras provehidas por libreros flamencos, franceses y suizos. Después de mediados de siglo, y sobre todo durante los años sesenta y setenta del siglo XVIII, un número notable de libreros y comerciantes, asentados mayormente en ciudades mediterráneas, establecieron relaciones con impresores de la república de Venecia. Entre los impresores venecianos destacó la casa Remondini, la cual consiguió introducir en la Península Ibérica libros, estampas y papeles pintados con notable éxito. En este artículo se analiza la relación comercial entre Josep Bro, librero de Girona, y la casa Remondini, un ejemplo paradigmático de la naturaleza de estos vínculos.
La desautomatización de las unidades fraseológicas en los titulares deportivos
Authors: Guerrero Salazar Susana
Published: September 2017

El artículo analiza la desautomatización de las unidades fraseológicas en los titulares de las portadas de los principales diarios deportivos españoles. Se sigue un enfoque pragmático, ya que la desautomatización de las UF funciona en los titulares como un procedimiento de intensificación lingüística. La desautomatización puede ser exclusivamente semántica, debido fundamentalmente a la intertextualidad, es decir, al cambio de significado que se genera cuando la forma canónica, procedente de otros discursos (sobre todo el cinematográfico y televisivo, el publicitario, el musical, el militar, el religioso, el político y el histórico), se inserta en la portada de un diario deportivo. No obstante, lo usual es que la desautomatización semántica se combine con uno o varios tipos de modificación formal, como pueden ser la sustitución, la adición, la supresión, la fusión o el cambio de modalidad oracional.
Cancioneiro da Ajuda, cantigas 180-183
Authors: Barberini Fabio
Published: September 2017

Le cantigas A180-A182 sono tràdite dal solo canzoniere da Ajuda in uno dei 7 fogli rinvenuti nella Biblioteca Municipal di Evora. L’attribuzione dei testi sarebbe, almeno in linea di principio, contesa tra Gonçal’Eanes do Vinhal e Johan Perez d’Avoim, ma la maggior parte degli studiosi inclina verso il secondo trovatore. Questo contributo presenta l’edizione critica dei 4 componimenti (con una nuova ipotesi testuale per A180, trasmessa dall’unico testimone in forma gravemente mutilata) e propone un riesame della questione attributiva. Se dal punto di vista lessicale e retorico non emergono elementi che permettano di sciogliere il nodo attributivo, la scarsa originalità metrica delle cantigas A180-A183 permette invece di orientare (ancorché non risolvere) l’attribuzione a favore di Johan Perez de Avoim
NEUROTEISĖ: KELETAS FUNDAMENTALIŲ ĮŽVALGŲ APIE TEISMINIŲ SPRENDIMŲ PRIĖMIMĄ
Authors: Valančienė Dovilė
Published: September 2017

Straipsnyje konceptualiai apžvelgiamas dviejų disciplinų – neuromokslo ir teisės dialogas, nagrinėjama keletas fundamentalių neuromokslo įžvalgų apie sprendimų priėmimą ir teismų sprendimų priėmimą bei siekiama atsakyti į klausimą, kaip būtų galima pagerinti teismų sprendimų priėmimą.
Disparities in the Intensity of End-of-Life Care for Children With Cancer
Authors: Johnston Emily E. , Alvarez Elysia , Saynina Olga , Sanders Lee , Bhatia Smita , Chamberlain Lisa J.
Published: September 2017

BACKGROUND:

Many adult patients with cancer who know they are dying choose less intense care; additionally, high-intensity care is associated with worse caregiver outcomes. Little is known about intensity of end-of-life care in children with cancer.

METHODS:

By using the California Office of Statewide Health Planning and Development administrative database, we performed a population-based analysis of patients with cancer aged 0 to 21 who died between 2000 and 2011. Rates of and sociodemographic and clinical factors associated with previously-defined end-of-life intensity indicators were determined. The intensity indicators included an intense medical intervention (cardiopulmonary resuscitation, intubation, ICU admission, or hemodialysis) within 30 days of death, intravenous chemotherapy within 14 days of death, and hospital death.

RESULTS:

The 3732 patients were 34% non-Hispanic white, and 41% had hematologic malignancies. The most prevalent intensity indicators were hospital death (63%) and ICU admission (20%). Sixty-five percent had ≥1 intensity indicator, 23% ≥2, and 22% ≥1 intense medical intervention. There was a bimodal association between age and intensity: ages <5 years and 15 to 21 years was associated with intense care. Patients with hematologic malignancies were more likely to have high-intensity end-of-life care, as were patients from underrepresented minorities, those who lived closer to the hospital, those who received care at a nonspecialty center (neither Children’s Oncology Group nor National Cancer Institute Designated Cancer Center), and those receiving care after 2008.

CONCLUSIONS:

Nearly two-thirds of children who died of cancer experienced intense end-of-life care. Further research needs to determine if these rates and disparities are consistent with patient and/or family goals.
Influence of oral application of Enterococcus faecium AL41 on TGF-β4 and IL-17 expression and immunocompetent cell distribution in chickens challenged with Campylobacter jejuni
Authors: Letnická Alica , Karaffová Viera , Levkut Mikuláš , Revajová Viera , Herich Róbert
Published: September 2017

Campylobacteriosis is mainly caused by infection with Campylobacter jejuni following consumption or handling of Campylobacter-contaminated poultry meat. The aim of this study was to investigate the effect of probiotic Enterococcus faecium AL41 on TGF-β4 and IL-17 expression and on immunocompetent cell distribution after C. jejuni infection in broiler chicken, as a second part of the previous study of Karaffová et al. (2017). Accordingly, day-old chicks were randomly divided into four experimental groups of 10 chicks each (n = 10): control (C), E. faecium AL41 (EFAL41), C. jejuni CCM6191 (CJ), and combined E. faecium AL41 + C. jejuni CCM6191 (EFAL41 + CJ). Samples from the caecum were collected on days 4 and 7 post Campylobacter infection (dpi), for the isolation of mRNA of TGF-β4, IL-17 and for immunohistochemistry. The relative mRNA expression of TGF-β4 was upregulated in the combined (EFAL41 + CJ) group compared to other groups during both samplings, but the expression of IL-17 was downregulated. Similarly, the highest density of CD3+ was detected in the combined group at 7 dpi, but the number of IgA+ cells was increased in both groups with EFAL41. It was concluded that the EFAL41 probiotic E. faecium strain can modulate the expression of selected cytokines (upregulation of TGF-β4 but downregulation of IL-17 relative expression), and activate IgA-producing cells in the caeca of chicks infected with C. jejuni CCM6191.
Preliminary results on the interactive effects of deoxynivalenol, zearalenone and fumonisin B1 on porcine lymphocytes
Authors: Kachlek Mariam , Szabó-Fodor Judit , Blochné Bodnár Zsófia , Horvatovich Katalin , Kovács Melinda
Published: September 2017

Fusarium mycotoxins, such as fumonisin B1 (FB1), deoxynivalenol (DON) and zearalenone (ZEN), frequently co-occur in feed raw materials and their presence is ubiquitous. The aims of this study were to determine the concentration that inhibits cell viability by 50% (IC50 values) for each mycotoxin (after 24, 48 and 72 h) and to investigate their combined effects in binary (DON + ZEN: DZ, DON + FB1: DF, FB1 + ZEN: FZ) and ternary (DFZ) mixtures using cyto- and genotoxicity on porcine lymphocytes as endpoints. The potency of cytotoxicity of the three toxins in an increasing order was FB1 < ZEN < DON. The range of IC values depending on the period of exposure was 0.31–0.42 μg/ml and 16.6– 22.9 μg/ml for DON and ZEN, respectively, and 101.15 μg/ml for FB1 (50% viability was reached only after 72 h). The main interaction observed was antagonism regarding cytotoxicity. Lower and higher sets of concentrations were used for the genotoxicity (comet assay) experiments. When lower concentrations were used, antagonism was again the main interaction observed. However, at higher concentrations an antagonism was confirmed only for DFZ, whereas for DZ and FZ a synergism was observed. Interactions of DF were inconsistent in different exposure periods in both series of experiments. Further studies with additional endpoints should be performed (e.g. DNA fragmentation, protein synthesis) in order to elucidate the mechanisms underlying the interactions observed.
Expression of iNOS, COX-2 and VEGF in canine mammary tumours and non-neoplastic mammary glands: Association with clinicopathological features and tumour grade
Authors: Anadol Elvan , Yar Saglam Atiye Seda , Gultiken Nilgun , Karakas Kubra , Alcigir Eray , Alkan Hasan , Kanca Halit
Published: September 2017

The aim of the present study was to investigate the relationship between the expression of iNOS, COX-2 and VEGF mRNA levels and malignancy degree in canine malignant mammary tumours. Thirty-five bitches presented with the complaint of mammary masses, aged 6–10 years and representing different breeds, were used. The expressions of iNOS, COX-2 and VEGF mRNA levels were significantly higher in both benign and malignant tumours than in the adjacent nonneoplastic mammary glands (P < 0.05). The iNOS, COX-2 and VEGF mRNA expression levels of grade 2 tumours were higher than those of grade 1 tumours; however, the highest expression levels were detected in grade 3 tumours. Thus, increased iNOS, COX-2 and VEGF gene mRNA levels were found to be related with the histological grade of malignancy in dogs with mammary tumours.
Are higher blood flow restriction pressures more beneficial when lower loads are used?
Authors: Dankel SJ , Jessee MB , Buckner SL , Mouser JG , Mattocks KT , Loenneke JP
Published: September 2017

The application of blood flow restriction during low-load resistance exercise has been shown to induce muscle growth with high or low restriction pressures, however, loads lower than 20% one-repetition maximum (1RM) remain unexplored. Fourteen trained individuals completed six elbow flexion protocols involving three different loads (10%, 15%, and 20% 1RM) each of which was performed with either a low (40% arterial occlusion) or high (80% arterial occlusion) pressure. Pre- and post-measurements of surface electromyography (sEMG), isometric torque, and muscle thickness were analyzed. An interaction was present for torque (p < 0.001) and muscle thickness (p < 0.001) illustrating that all increases in pressure and/or load resulted in a greater fatigue and muscle thickness. There was no interaction for sEMG (p = 0.832); however, there were main effects of condition (p = 0.002) and time (p = 0.019) illustrating greater sEMG in the 20% 1RM conditions. Higher blood flow restriction pressures may be more beneficial for muscle growth when very low loads are used.
Cilostazol enhances atorvastatin-induced vasodilation of female rat aorta during aging
Authors: Nurullahoğlu-Atalık KE , Kutlu S , Solak H , Koca R Özen
Published: September 2017

Statins have cholesterol-independent effects including an increased vascular nitric oxide activity and are commonly used by patients with cardiovascular disease. Such patients frequently have cardiovascular diseases, which may be treated with cilostazol, a platelet aggregation inhibitor. This study was designed to investigate whether combined use of cilostazol would increase the inhibitory effect of statin on vascular smooth muscle and how maturation would affect these responses. Female Wistar rats, aged 3–4 months (young) and 14–15 months (adult), were sacrificed by cervical dislocation and the thoracic aorta was dissected and cut into 3- to 4-mm-long rings. The rings were mounted under a resting tension of 1 g in a 20-ml organ bath filled with Krebs–Henseleit solution. Rings were precontracted with phenylephrine (10−6 M), and the presence of endothelium was confirmed with acetylcholine (10−6 M). Then, the concentration–response curves were obtained for atorvastatin alone (10−10 to 3 × 10−4 M; control) and in the presence of cilostazol (10−6 M) in young and adult rat aortas. This experimental protocol was also carried out in aorta rings, which had been pretreated with NG-nitro-l-arginine methyl ester (l-NAME, 10−4 M). Atorvastatin induced concentration-dependent relaxations in young and adult rat thoracic aorta rings precontracted with phenylephrine. The pIC50 value of atorvastatin was significantly decreased in adult rat aortas. In addition, pretreatment of aortas with cilostazol enhanced the potency of atorvastatin in both young and adult aortas. Incubation with l-NAME did not completely eliminate the relaxations to atorvastatin in the presence of cilostazol. These results suggest that combined application of cilostazol with atorvastatin was significantly more potent than atorvastatin alone. Combined drug therapy may be efficacious in delaying the occurrence of cardiovascular events.
PEMILIHAN JENIS TANAMAN AIR SEBAGAI NAUNGAN PADA PENDEDERAN IKAN GABUS (Channa striata)
Authors: Sirodiana Sirodiana , Irawan Deni
Published: September 2017

Ikan gabus merupakan ikan predator yang aktif pada malam hari dan senang bersembunyi. Untuk mengembangkan budidaya ikan gabus pada kolam terkontrol, perlu mempelajari kebiasaan hidupnya di alam, salah satunya penggunaan naungan/shelter. Tujuan dari kegiatan ini adalah mengetahui jenis tanaman air terbaik untuk dijadikan naungan pada pendederan ikan gabus. Kolam yang digunakan berukuran 2 m x 4 m x 1 m. Kedalaman air pada tiap-tiap kolam 50 cm. Benih gabus yang digunakan pada saat awal penebaran berukuran bobot 3,30 ± 0,98 g dan panjang 7,13 ± 1,02 cm. Padat tebar pada tiap-tiap kolam sebanyak 100 ekor/kolam. Jumlah presentasi naungan sebanyak 50% dari jumlah luasan permukaan air. Tanaman air yang digunakan sebagai perlakuan adalah: A) kayu apu, B) eceng gondok, dan C) eceng sawah. Hasil pengamatan menunjukkan sintasan dan pertumbuhan terbaik diperoleh pada kolam yang menggunakan naungan dari jenis eceng sawah. Sehingga disarankan untuk pendederan ikan gabus menggunakan naungan dari jenis eceng sawah.
PEMANTAUAN KUALITAS AIR BOT (BAHAN ORGANIK TOTAL) DAN TAN (TOTAL AMONIAK NITROGEN) DALAM OPTIMALISASI TEKNOLOGI YUMINA-BUMINA
Authors: Mustika Indrayana , Rahmayani Rani
Published: September 2017

Yumina-bumina adalah teknik budidaya yang memadukan antara sayuran (yu) dengan ikan (mina), dan buah-buahan (bu) dengan ikan (mina). Parameter kualitas air yang penting sistem yumina-bumina antara lain adalah BOT (bahan organik total) dan TAN (total amoniak nitrogen). Jika nilai parameter-parameter tersebut melampaui batas, dapat membahayakan kehidupan ikan yang dipelihara. Kegiatan ini bertujuan untuk memantau kualitas air pada parameter BOT dan TAN dalam kegiatan optimalisasi sistem yumina-bumina dengan unit proses pengendapan dan biofiltrasi yang berbeda yang dilakukan melalui sampling setiap dua minggu sekali selama delapan minggu. Hasil pengukuran tersebut menunjukkan bahwa nilai kadar BOT pada unit yumina-bumina yang memiliki satu buah bak pengendapan (unit A), satu buah bak pengendapan dan satu buah bak biofilter (unit B), serta dua buah bak pengendapan dan satu buah bak biofilter (unit C) mengalami kenaikan yang pada sampling keempat, sedangkan kadar TAN cenderung mengalami penurunan. Nilai kadar BOT dan TAN pada unit A cenderung lebih besar daripada unit B dan C, sedangkan unit C memiliki kadar BOT dan TAN yang terendah. Dengan demikian, kualitas air parameter BOT dan TAN pada unit yumina-bumina yang memiliki dua buah bak pengendapan dan satu buah bak biofilter lebih baik daripada unit yumina-bumina yang memiliki satu buah bak pengendapan dan satu buah bak biofilter maupun unit yumina-bumina yang hanya memiliki satu buah bak pengendapan.
SCREENING PRIMER PADA ANALISA RAPD GENETIK IKAN UCENG (Nemachilus sp.) POPULASI TEMANGGUNG, PURWOKERTO, CIJERUK, DAN CIAMPEA
Authors: Sundari Sri , Priadi Bambang
Published: September 2017

Ikan uceng termasuk ikan yang memiliki nilai ekonomi yang cukup tinggi di beberapa daerah di Indonesia. Dalam rangka pelestarian dan pengembangan budidaya ikan uceng maka dilakukan evaluasi keragaman genetik. Kegiatan ini bertujuan untuk mendapatkan primer yang tepat untuk analisis Random Amplified Polymorphic DNA (RAPD) genetik ikan uceng sebagai dasar untuk analisis keragaman genetik ikan uceng. Dalam penelitian ini primer yang digunakan adalah primer OPA-01—10. Sampel yang digunakan adalah sirip ikan uceng yang berasal dari Temanggung, Purwokerto, Cijeruk, dan Ciampea. Berdasarkan hasil screening terhadap 10 jenis primer, maka didapatkan primer OPA-08 yang dapat mengamplifikasi DNA ikan uceng dengan jumlah fragmen antara 5-16 dan ukuran band/pita DNA 220-3.000 bp.
Reservoirs optimization with dynamic programming
Authors: Phuong Phan Thi Thu , Han Dao Thi Ngoc , Lai Hoang Van , Tri Bui Minh
Published: September 2017

Differential Evolution (DE) and Dynamic Programming (DP) are important optimal methods in reservoir regulation. In the previous work [1], we presented the outline of DE, and applied it into Pleikrong reservoir, a big one in the Highland of Vietnam for dry season of 2010 year. Continuing from that, in this work, we present the outline of DP and then again, apply it to Pleikrong reservoir; and also apply it to Ialy, the biggest reservoir in Sesan cascade in the Highland of Vietnam; to reach optimal regulation for the maximum power production in the dry season of two years: 2010 and 2012. The results getting from DP are compared to the results by using DE. The results by these two methods have the same trend of releases which is storing the water at the beginning and significantly releasing at the end of the calculation time.
Numerical and experimental studies for crack detection of a beam-like structure using element stiffness index distribution method
Authors: Khoa Nguyen Viet , Nguyen Quang Van , Kien Nguyen Dinh , Mai Cao Van , Thao Dao Thi Bich
Published: September 2017

In this paper, numerical and experimental studies for crack detection of structures using "element stiffness index distribution" are presented. The element stiffness index distribution is defined as a vector of norms of sub-matrices corresponding to element stiffness matrices calculated from the reconstructed global stiffness matrix of the beam. When there is a crack at an element, the element stiffness index of that element will be changed. By inspecting the change in the element stiffness index distribution, the crack can be detected. A significant peak in the element stiffness index distribution is the indicator of the crack existence. The crack location is determined by the location of the peak and the crack depth can be determined from the height of the peak. The global stiffness matrix is calculated from the measured frequency response functions instead of mode shapes to avoid limitations of the mode shape-based methods for crack detection. Numerical simulation results for the cases of beam-like structures are provided. The experiment is carried out to justify the efficiency of the proposed method.
The Decline in Lending to Lower-Income Borrowers by the Biggest Banks
Authors: Bhutta Neil , Laufer Steven , Ringo Daniel R.
Published: September 2017

Data collected under the Home Mortgage Disclosure Act (HMDA) reveal that the largest banks have significantly reduced their share of mortgage lending to low- and moderate-income (LMI) households in recent years.
Are Rising Home Values Restraining Homebuying for Lower-Income Families?
Authors: Bhutta Neil , Laufer Steven , Ringo Daniel R.
Published: September 2017

Since bottoming out in 2012, house prices in the U.S. have recovered rapidly. According to Zillow, the median home value has been growing about 6 percent per year. While incomes have also been recovering, they have not quite kept pace with home prices. This note uses data reported under the Home Mortgage Disclosure Act (HMDA), along with income data from the ACS, and house price data from Zillow, to explore whether families in such areas, particularly lower-income families, are being priced out of homeownership as a result.
Compromised Agency: The Case of BabyLegs
Authors: Liboiron Max
Published: September 2017

The concept of agency is ubiquitous in STS, particularly regarding cases of alternative ways of knowing and doing science such as civic, citizen, and feminist sciences, among others. Yet the focus on agency often glosses over the constraints placed on agents, particularly within asymmetrical power relations. This article follows the case of BabyLegs, a do-it-yourself monitoring tool for marine microplastic pollution, and the attempt to keep the technology open source within an intellectual property (IP) system set up to privatize it. The tactics used to design BabyLegs as a feminine, silly, doll-tool to discredit the device in the eyes of an IP system that valued traditional gender roles lead to the eventual success of keeping the device open source. Yet, those same tactics also reinforced and reproduced the structures of power and essentialism they were designed to resist. I characterize this technological ambivalence as compromise, and argue that all agency exercised within asymmetrical power relations is compromised. This is not to say resistance is futile, but that agency is never pure, and this recognition lets us be more intentional in how we might compromise as practitioners of diverse scientific knowledges.
Participatory Air Monitoring in the Midst of Uncertainty: Residents’ Experiences with the Speck Sensor
Authors: Matz Jacob Robert , Wylie Sara , Kriesky Jill
Published: September 2017

How do participants engage in at-home air monitoring in the midst of uncertain exposures to airborne emissions associated with unconventional natural gas development (UNGD) activities? We investigate residents’ experiences with the “Speck” particulate matter sensor with an emerging environmental health resource center called the Southwest Pennsylvania Environmental Health Project (EHP).  In response to the gaps in knowledge about the health impacts of UNGD and the growth citizen science tools, participatory environmental monitoring (PEM) projects have taken off in shale gas communities. Using interview and survey data from residents, advocates, and activists we show that residents use the Speck as: 1) “environmental health thermometers” to make real time decisions based on readings; 2) real-time tools of exposure-validation to immediately validate or invalidate suspicions of exposure; 3) “epistemic objects” or tools manipulated in exploratory ways to understand their efficacy in monitoring UNGD; and 4) passively by those who chose to rarely interact with the monitors and rather waited for overall analysis of results.  While PEM’s have been critiqued for potentially passing the burden of monitoring onto communities, our research shows PEM, when connected with research and public health organizations like EHP, can both empower individuals by increasing their perceived and actual agency and build collective knowledge by producing novel scientific findings. The modes of participation identified here each imply individual and community-level outcomes. When connected with an organization like EHP, Speck monitoring enabled participating individual the latitude to develop their own research and make immediate use of the data, while also creating data useful for aggregated scientific analyses that provoke new questions about the health risks associated with UNGD.
Living with Oil and Gas and Practicing Community Conducted Science
Authors: Thomas Deborah
Published: September 2017

Deborah Thomas is an activist, citizen scientist and Wyoming resident. In this paper she describes experiences gleaned from local efforts to effect positive change and resistance to shale gas development in her own community. Meeting the challenges of development requires collaboration among community members, including farmers, rural residents, city dwellers, non-profits, doctors, scientists, and academics.   Creation of and access to scientific information are crucial.
Pastoral Care for the Sick and the Dying
Authors: Surozhskij A.
Published: September 2017

Metropolitan Anthony of Sourozh (nee Andrey Borisovich Bloom, 19.06.1914— 04.08.2003) was the Head of the Russian Orthodox Church in Great Britain and Ire- land from 1957 till 2003, from 1966 till 1974 he also served as the Patriarchal Exarch in Western Europe. Honoris Causa Doctor of Divinity of Aberdeen and Cambridge Universities, Hon. DD of Moscow and Kiev Spiritual Academies for theological and missionary work. His word, broadcast by the BBC and spread by means of Samizdat was greatly valued by the believers in the USSR. His books on prayer and spirituality have been translated in many languages worldwide. From 1991 his texts are being widely published in Russia.
Dietrich Bonhoeffer’s “Religionless Christianity”: Secular and Divine
Authors: Nyrkov A.
Published: September 2017

Dietrich Bonhoeffer’s “Religionless Christianity” brought its author a scandal- ous reputation. Bonhoeffer’s name is associated with serious changes in the life of Western society in the second half of the twentieth century. Pastor Bonhoeffer was not afraid to go far in his statements. One of the most famous his ecclesiasti- cal and social insights associated with the “religionless Christianity” project, the principal features of which are discussed in the article. The main conclusion is that the “religionless Christianity” project, conceived by the author for the extensive missionary purpose is ultimately proving to be self-destructive factor. This article is the continuation of “Religion and the Human in Dietrich Bonhoeffer’s Religion- less Christianity” [Нырков 2014].
Function of Faith in the daseinsanalytical Psychotherapy
Authors: Lyzlov A.V.
Published: September 2017

The article briefly presents the history of daseinsanalysis as a direction of psychotherapy. Two fundamentally different approaches within the framework of daseinsanalysis are compared: 1) the initial for daseinsanalytical psychotherapy approach by M. Boss, and 2) the later approach by A. Holzhey-Kunz. The aim of the article is to demonstrate that the basis of differences between these two approaches lies in the factor of faith, understood in accordance with the philosophy of Kierkegaard, a very important author for the thought of Heidegger and for understanding of daseinsana- lytical psychotherapy. Two a/n approaches are systematically set out so that a reader can make the acquaintance of them.
The Phenomenology of Intersubjective Relationships in the Person’s Life-World
Authors: Fedoseeva A.M. , Pirlik G.P.
Published: September 2017

Current article presents results of a qualitative research dedicated to the phenomenology of intersubjective relationships in person’s infantile, realistic, value life-worlds. The characteristics of the anthropological image of the Other as well as the basic attitudes that define relationship between the subjects life-world and the Other are described.
Extraction and Purification of Fucoxanthin from Sargassum sp. as Anti-acne
Authors: Renhoran Mawaddah , Noviendri Dedi , Setyaningsih Iriani , Uju U.
Published: September 2017

Fucoxanthin is a pigment of a carotenoid group in brown seaweed. Fucoxanthin has high biological activity, therefore, it is suitable for the antibacterial activity. Acne is a disease caused by bacterial activity. The purposes of this study were to obtain fucoxanthin active compounds of Sargassum sp. and to determine antibacterial activity of crude extract and fucoxanthin active fraction as anti-acne compounds at bacteria causing acne. Extraction of fucoxanthin used maceration method and its purification was carried out by silica gel column method. Antibacterial activity test used disk diffusion method.  The yield of crude extraction and yield of active fraction of Sargassum sp. were 0.54% and 0.13% respectively. Fucoxanthin active fraction was identified at 0.53 Rf value. The total content of fucoxanthin was 0.47 mg/g. The functional groups of fucoxanthin active fraction consisted of alcohols, alkanes, methyl, alkenes, esters and aromatic alkenes. Fucoxanthin active fraction had anti-acne activity at 125, 250, 500 and 1,000 ug/disk against of Propionibacterium acnes and at 500 and 1,000 ug/disk against of Staphylococcus aureus.
AVALIAÇÃO DO CONSUMO DE COMBUSTÍVEL DE UM CONJUNTO MOTOMECANIZADO NO MANEJO DE PLANTAS DANINHAS NA CULTURA DA ACEROLA (Malpighia Ermaginata) EM CULTIVO ORGÂNICO
Authors: Santos L. F. A. , Batistas C. D. , Vieira A. D. , Fernandes F. R. B. , Albiero D.
Published: September 2017

A cultura da acerola possui grande importância para a fruticultura do país, principalmente na região Nordeste, onde primeiro a cultura foi estabelecida comercialmente no Brasil pela Universidade Rural de Pernambuco em 1955. O controle de plantas daninhas é de suma importância para o bom desenvolvimento das culturas, em culturas perenes esse controle é em grande parte viável pelo método mecânico, como roçadoras, pois as entre linhas de plantios possuem um espaçamento necessário para o conjunto trator-implemento realizar tal processo, esse método mostra o mais viável, quando comparado com o de controle manual e químico, pois o maquinário consegue tratar uma área superior da atividade realizada manualmente pelo homem e do ponto de vista ambiental, não faz-se o uso de substâncias perigosas ao ambiente como são os herbicidas usados no tratamento químico de plantas daninhas. O presente trabalho objetivou avaliar o consumo de combustível em um conjunto trator-roçadora, com três tipos de roçadoras e quatro diferentes combinações de marcha e rotação, nas entre linhas de plantio em um pomar de produção orgânica de acerola no município de Ubajara no estado do Ceará. Os resultados mostraram que houve diferença significativa nos consumos dos tratamentos testados, o que demonstra a importância desse tipo de testes visando à economia em operações mecanizadas.
Etiology, pathophysiology, diagnosis and management of diabetics’ foot ulcer
Authors: Rosyid Fahrun Nur
Published: September 2017

Diabetic foot ulcers (DFU) is a lesion of all layers of skin, necrosis or gangrene that occurs in the soles of the feet in diabetes mellitus (DM) patients, caused by: (1) causative factor (peripheral neuropathy, high foot plantar pressure and trauma); (2) contributive factors (atherosclerosis and diabetes). The treatments of diabetic ulcers consist of determining and repairing the underlying cause of ulcer, good wound care and prevention of ulcer recurrence. The cause of diabetic ulcers can be determined by deep anamnesis and physical examination. DFU therapy includes necrotomy/debridement, reducing the load/pressure on the offensive area, manage the infection by diagnosing the type of bacteria, providing adequate antibiotics and ulcer treatment using wound dressing clean and moist.
Ankle spanning external fixator with limited internal fixation for distal tibial extra-articular fractures
Authors: Goel Siddharth , Elhence Abhay
Published: September 2017

Background: Fractures of the distal tibia are among the most difficult fractures to treat. The short distal segment presents difficulty in choosing the appropriate fixation method. The greatest challenge lies in the relatively tight soft tissue around the ankle. As a result, it has been a recent interest in treating these fractures with external fixation and limited internal fixation. The external stable fixation methods used are tubular or ring fixators, with or without immobilising the ankle. This minimally invasive nature of the surgery can avoid catastrophic wound complications like dehiscence, implant exposure and infection.Methods: 18 patients with extra-articular distal tibial fractures (AO Type 43A) were treated with the technique of ankle spanning external fixation. Lag screws or K-wires were supplemented for limited internal fixation when required. Fibula was stabilised in all cases. Intra- articular and Compound fractures were excluded. In addition to union at fracture site, ankle pain and motion was noted in each follow-up.Results: The mean follow-up was 25 months. Of the 18 patients included all but one fractures united with an average healing time of 16 to 18 weeks. Ankle pain and motion was graded according to Mazur modified by Teeny and Wiss clinical scoring system. 15 of them had excellent or good results, 2 had fair results. One patient had poor result. Five pin tract infections occurred. 17 patients had no evidence of osteoarthritis after completing follow up of at least 2 years.Conclusions: Distal tibial fractures are complex injuries, not only regarding the bony component, but also in terms of the management of the soft tissue problem. Ankle Spanning External Fixator with Limited Internal fixation is a relatively simple and cost-effective method for treating these fractures, achieving union and also maintaining ankle function.
Fine needle aspiration cytology- an accurate method for diagnosis of cutaneous and subcutaneous metastases
Authors: Rastogi Nupur
Published: September 2017

Background: Cutaneous metastases from carcinoma are relatively uncommon, usually representing late events in the course of internal malignancies and indicate a dismal outcome of patients. Aim of the study was undertaken to evaluate the role of FNAC as a diagnostic tool for diagnosis of cutaneous metastases of various internal malignancies as it is of great value in the early diagnosis.Methods: Study of cutaneous metastases was undertaken for the period from April 2013 to July 2017. Out of over 12000 cytology cases, 25 cases were diagnosed as cutaneous metastases. Fine needle aspiration was done using 22-gauge needle without anaesthesia and smears were air dried and stained with MGG.Results: Out of 25 patients diagnosed with cutaneous metastases on cytology, 11 were males and 14 females with age ranging from 20-75 years. Chest wall was the most common site of metastases. Adenocarcinoma and Non-Hodgkin’s Lymphoma were the most common cytomorphological types observed.Conclusions: FNAC is minimally invasive, safe, rapid and reliable method for the diagnosis of cutaneous metastases.
Comparative evaluation of clonidine versus fentanyl as adjuvants for epidural anaesthesia with 0.75% ropivacaine for day care knee arthroscopy: a double-blind study
Authors: Bansal Manoranjan Kumar , Gupta Kumkum , Masoodi Tahir Ahamad , Singh V. P. , Rastogi Bhawana , Buchh Aqsa
Published: September 2017

Background: Day care knee arthroscopy can be performed with general anesthesia, central neuraxial blockade and peripheral nerve blocks. The adjuvants to local anaesthetic may be used to enhance the duration of analgesia without increasing the duration of motor blockade. The present study compared the clinical efficacy of clonidine with fentanyl as adjuvants to epidural ropivacaine (0.75%) for day care knee arthroscopy.Methods: Sixty adult patients of both gender of ASA physical status I and II scheduled for day care knee arthroscopy under epidural anaesthesia, were randomized into two groups of 30 patients each to receive either 15 ml of 0.75% ropivacaine with 1 ml of clonidine 50 µg (Group RC) or with 1 ml of fentanyl 50 µg (Group RF). Groups were compared for onset and duration of sensory and motor blockade and post-anesthesia discharge score (PADS) as primary end points. Intraoperative hemodynamic changes, time taken to void, total duration of hospital stay and any adverse effects were evaluated as secondary end points.Results: The onset of complete sensory block to T10 (15.4±4.7 versus 17.5±3.8 minutes) and time to achieve complete motor block (23.7±3.3 versus 26.9±1.4 minutes) was earlier in patients of Group RC. Intraoperative hemodynamic changes were comparable. Time to achieve PADS was earlier in patients of Group RF (6.37±1.08 versus 7.11±0.49 hour) with no statistical significant difference. Total duration of hospital stays (7.81±1.31 versus 8.27± 1.18 hour) was also comparable.Conclusions: Clonidine and fentanyl, both can be used as epidural adjuvant to 0.75% ropivacaine for day care knee arthroscopy as they could enhance the duration of analgesia without affecting the hospital stay.
A study of metastatic lesions of lymph nodes by fine needle aspiration cytology
Authors: Meena Pratibha , Mishra Ranu Tiwari
Published: September 2017

Background: FNAC is rapidly emerging as a useful tool in the diagnosis of metastatic lesion of lymph nodes. FNAC not only confirms or excludes metastasis in a case of a known primary malignancy but, also, in most cases helps to detect occult primary malignancy. Aim of present study was to determine the frequency of metastatic lesions of lymph nodes.Methods: This retrospective study was done of all metastatic lymph node lesions reported on FNAC, in the department of pathology, NSCB medical college, Jabalpur from January 2014 to December 2014 (One Year).Results: Total cases of 400 lymph node aspiration were done, of which 120 cases were clinically suspicious of metastasis. Cytology results were positive for metastasis in 97 cases (80.8%). The most common site of aspiration was cervical lymph nodes (75.2%). Maximum number of cases of metastasis were in 51-60 years age group with male predominance (male:female 2.6:1). The most common metastasis was squamous cell carcinoma seen in 74 cases (76.2%), followed by metastatic mammary carcinoma (10.3%), remaining were adenocarcinoma, undifferentiated carcinoma, malignant melanoma, papillary thyroid carcinoma and transitional cell carcinoma.Conclusions: FNAC is a rapid, safe and cost-effective technique. It gives early and accurate results with minimal invasion and reduces the need for surgical biopsies, thus saves cost and time to reach the final diagnosis. It is therefore concluded that FNAC is a useful tool in diagnosing metastatic lesions of lymph nodes with a good certainty.
A study on malassezia micro flora in the skin of healthy individuals in North Kerala, India
Authors: V. S. Remya , B. Arun , P. M. Sheeba , Kokkayil Pratyusha
Published: September 2017

Background: Malassezia spp are accounted for approximately 60-90% of the total cutaneous fungal micro biota. An enhanced understanding of the distribution of Malassezia spp in healthy individuals is necessary to gain insight to involvement of these species in human skin disorders particularly in pityriasis versicolor. The aim of this study was to assess the Malassezia micro flora of healthy individuals and to identify species variation with different body sites, gender and age groups.Methods: A total of 120 apparently healthy men and 120 women without any skin diseases or who were not treated for Malassezia associated skin diseases were selected for the study. The specimens consisted of scrapings collected from chest, back and neck from each control subject totaling 720 sites.Results: The recovery rate of Malassezia was positive in case of 452 (62.78%) of 720 sites sampled, while the remaining 268 (37.22%) were found to be negative. Recovery rate of Malassezia was highest in chest with 83.33% positive cases, followed by the back with 73.33% and the neck 31.67%. M. globosa was identified as the common species (46.46%) followed by M. furfur (25%) and M. restricta (22.56%). No significant difference was present (P > 0.05) in distribution of species with different body sites, gender and age groups.Conclusions: The overall colonization rate of Malassezia spp in normal healthy individuals found in this study was 62.78%. M. globosa was identified as the common species (46.46%).
Obstructive jaundice due to forgotten biliary stent- a rare case report
Authors: Deolekar Sandesh , Mahapatra Bibekananda , Murali Sridevi , Ali Sheena , Chheda Karna , Khan Naseem
Published: September 2017

There are many studies about the biliary stents, however there is a little information about the long-term complications of forgotten biliary stents except a few case reports. We present a 68-years-old female patient who presented with abdominal pain, vomiting and jaundice. The patient had had a biliary prosthesis inserted 114 months (9.5 years) earlier for treatment of multiple common bile duct calculi, post cholecystectomy done in 1993. Imaging investigations evidenced the presence of obstructive jaundice and the biliary stent with gall stones adherent on its surface. After the failure of an endoscopic extraction attempt, surgical intervention ensured the removal of the stent and the gallstones formed on its surface. This case represents the rarity of such a complication after biliary stenting. At the same time, it emphasizes the need for postoperative follow-up, to avoid this kind of complication.
Scientific and Editorial (S & E) Board
Authors: . .
Published: September 2017

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Cloning and Over-expression of xynB Gene of Bacillus subtilis subsp. spizizenii W23 into Escherichia coli Origami Host Cells
Authors: Wahjudi Mariana , . Catherina , Wangunhardjo Nita Marcelia , Suryadjaja Ernest , Daniel Xavier
Published: September 2017

The xynB gene of Bacillus subtilis subsp. spizizenii W23 is predicted to encode a xylan 1,4-beta-xylosidase. Application of XynB enzymes in industries is wide. Production of this enzyme in its host cells is naturally restricted by repression process. It will give certain beneficial to over-expressed the enzymes in other host-cells under inducing promoter. This study aimed to clone the xynB gene from Bacillus subtilis subsp. spizizenii W23, to pMMB67EH plasmid, and to over-express the xynB gene in Escherichia coli Origami as host cells. The xynB gene was successfully amplified by polymerase chain reaction (PCR) technique using a pair of primers flanking the gene sequence and chromosomal DNA of the W23 strain as a template. The xynB gene inserted in recombinant plasmid was confirmed by PCR detection using primers pair’s specific for xynB gene and for the vector, then continued by restriction analyses.  The result showed that transformants clone 9 and 10 bear the recombinant pMMB-xynB plasmid. The xylanase activity of xynB gene in Escherichia coli Origami clone 10 was detected by sodium-dodecyl-sulfate polyacrylamide gel analyses and with addition of isopropyl-β-D-thio-galactoside (IPTG) as an inducer. The protein seem to be over-expressed as intra- and extra-cellular protein detected on SDS-PAGE gel. Result from xylan degrading activity on Luria-Bertani-xylan-IPTG plate with addition of Congo Red, showed that the cells with pMMB-xynB recombinant plasmid have clear zone around the colonies while the transformant bearing an empty plasmid showed no clear zone. It could be concluded that the xynB gene of Bacillus subtilis subsp.spizizenii W23 has been successfully been cloned on pMMB67EH plasmid and over-expressed in the Escherichia coli Origami cells as intra- and extra-cellular protein, as observed on SDS-PAGE gel analysis. The protein has activity on xylan degradation.
Composting of Corn By-Product using EM4 and Microorganism Azotobacter sp. as Composting Organism
Authors: Hendriani Nuniek , Juliastuti Sri Rachmania , Masetya Hamida Nuur , Saputra Imam Tianto Aditiyas
Published: September 2017

Nowadays the organic compost is very important for farmers because of its environmentally friendly character. However, the production technology of organic compost is not well-known yet for the farmers. This study aimed to utilize corn by-product compost as fertilizer for plants growth. Composting process was accelerated by addition of composting organism called as effective microorganism (EM4) and Azotobacter. Their composition were EM4:Azotobacter 1:1 ; 1:3, EM4 alone, Azotobacter alone and without addition of composting microorganism. The composting process was conducted in a composter for 15 d and mixed three times per day. The process should be carried out under controlled aerobic conditions. The observed parameters were carbon (C), nitrogen (N), phosphor (P), and potassium (K) content. The parameters was measured before and after composting process. The resulted compost were applied to the growing corns, chilis, and tomatoes as fertilizer. The result showed that the best compost was obtained on 3:1 composition of EM4 : Azotobacter. This composition was able to reduce 0.74 % carbon content, and increase 151.46 %, 147.9 %, and 238.42 % of N, P, K content respectively. Moreover this particular compost was able to bring 3.75 mm corn stem and 1.0 mm corn leaf growth per day, lead to harvesting of  two tomatoes and eight chilie
The Directions of Creation of Unique Technologies in Medicine on the Basis of New Generation of Biocompatible Materials and Implants With Shape Memory
Authors: Gunther V.E.
Published: September 2017

The article describes the main directions of creation of unique technologies in medicine on the basis of new generation of biocompatible materials and implants with shape memory effect (SME). Physical and biological fundamentals and principles of creating a new class of biocompatible superelastic TiNi-based materials were drafted. Manufacturing technique of TiNi-based materials with using the induction melting technique, self-extending high-temperature synthesis and powder metallurgy with a certain complex of properties for various fields of medicine have been developed.
Structural Features of TiNi-based Textile Materials and Their Biocompatibility with Cell Culture
Authors: Khodorenko V.N. , Anikeev S.G. , Kokorev O. V. , Mukhamedov M.R. , Topolnitskiy E.B. , Gunther V.E.
Published: September 2017

This study investigates the structural features of TiNi-based textile materials. It is established that woven materials have a regular cellular structure, while knitted mesh materials are characterized by presence of cells with various sizes both in the longitudinal and cross directions. The surface oxide layer of threads has a microporous structure that provides the improved adaptation in organism tissues. It is shown that the fibroblast colonization rate of the knitted mesh implants depends on the cell size and quantity of mesh knots. Smaller cells are quicker colonized. Mesh knots are the centers of the cell cling. The feature of cell interaction with the tread surface of various sizes is analyzed.
Martensite Transformations in the TiNi(Fe,Mo)Ag Alloys After Thermal Cycling
Authors: Baigonakova G.A. , Marchenko E.S. , Kolomiets L.A. , Chernysheva A.L. , Iliushenov V.N. , Gunther V.E.
Published: September 2017

This paper presents the results on influence of thermal cycling on martensite transformations in (TiNiFeMo)Ag alloys with silver additive up to 1.5 at.%. The analysis of temperature dependences of the electrical resistivity allows to determine the characteristic temperatures and construct the diagram of martensite transformations. The thermal cycling leads to the reduce in Ms temperature stabilizing the parent B2 phase in all considered cases of Ag additive. The strongest influence of thermal cycling on the Ms temperature was founded in alloy with 1 at.% Ag. Authors describe the factors leading to a change of the characteristic temperatures of martensite transformations during thermal cycling.
Crystallization Features of Porous TiNi Made by SHS
Authors: Yu. Yu.F. Yasenchuk , Artyuhova N.V. , Almaeva K.V. , Garin A.S. , Novikov V.A. , Gunther V.E.
Published: September 2017

The surface layers and fracture surfaces of porous titanium nickelide obtained by self-propagating high temperature synthesis (SHS) in a flow reactor in an argon atmosphere are studied by SEM and energy dispersive analysis. It is alleged that primary pores 5–15 µ in size and the related granular layer are formed due to segregation and capillary force effect during peritectic crystallization of some porous alloy areas. Coarsening and deformation of pores, as well as migration and growth of granular layers, is caused by reaction gases. Carbon and oxygen impurities present in the reaction gases and the protective atmosphere penetrate into the melt film on the pore surface to form strong and corrosion-resistant nanostructured layers of intermetallic carbides, nitrides and oxides.