bluuebunny/crossref_metadata_2025 huggingface dataset:
The Amendment to the Constitution of the Russian Federation concerning the Ideals of our Ancestors and Faith in God as the Basis for Sustainable Development of Russia
Authors: Osavelyuk A. M.
Published: October 2023

The paper, based on the analysis of research works of famous modern and pre-revolutionary constitutional scholars, philosophers, as well as the provisions of the Constitution of Russia, current legislation and law enforcement practice, shows the problems of sustainable development of Russia arising from the excessive reliance of mankind on environment and the global intensification of socio-economic development. The author determines new prospects for their resolution implementing the provisions of the Amendment included in the Constitution of the Russian Federation in 2020 and devoted to the ideals of our ancestors and faith in God as the basis of sustainable development, which are based on spiritual and moral values tested in practice by our ancestors during many centuries of the national statehood. Special attention is paid to the examination of the interaction and interrelation between the norms of religion, morality and law in creating a qualitative basis for sustainable development through the unity and social solidarity of the man, state institutions and civil society in ensuring the continuity of the statehood of Russia.
Morphological and molecular features of decidual endometrial cells in miscarriage
Authors: Gusarova Tatiana A. , Nizyaeva Natalia V. , Mikhalev Sergey A. , Tikhonova Natalya B. , Orgadeeva Darya A. , Mikhaleva Liudmila M. , Sharapova Olga V.
Published: October 2023

Decidualization is a dynamic, multistep process that results in the differentiation of elongated endometrial stromal cells into round, epithelioid-like decidual cells in response to increasing progesterone levels. Throughout pregnancy, decidual stromal cells play an important role by creating a tolerant microenvironment, the decidua, to suppress the maternal immune response and prevent rejection of the allogeneic fetus. Decidualization is considered significant not only in the establishment and maintenance of pregnancy, prevention of early losses, and modulation of the immune response but also in the control of the onset of labor, regulation of trophoblast invasion, and embryo selection. Decidual cells have immunomodulatory properties in relation to cells of innate and adaptive immunity. Pregnancy maintenance requires selective elimination of proinflammatory senescent decidual cells by activated uterine natural killer cells. Data on various populations of decidualizing endometrial stromal cells revealed subtypes with different functional characteristics, namely, predecidual, decidual, transitional, and senescent subpopulations. An increase in the number of the latter with a proinflammatory phenotype leads to miscarriages. This paper analyzes the literature data on decidualization and its role in the genesis of miscarriage and highlights the contribution of decidual stromal cells to the microenvironment and their direct or indirect influence on the recruitment, distribution, and function of immune cells, extracellular matrix remodeling, and placenta formation.
Sınava Hazırlanan Öğrencilerde Sınav Kaygısının Beslenme Durumu Üzerine Etkisi
Authors: RASHİDİ Mahruk , KANBUR Bahar Nur , YILDIRIM Gülay
Published: October 2023

Amaç: Bu çalışma sınava hazırlanan öğrencilerin sınav kaygısı ile beslenme alışkanlıkları arasındaki ilişkiyi değerlendirmek amacıyla planlanmıştır.

Yöntem: Tanımlayıcı, kesitsel ve ilişkisel tipte planlanan araştırmanın örneklemini İstanbul’da özel bir kolejde okuyan, lise ve üniversite sınavlarına hazırlanan 166 öğrenci oluşturmuştur. Veriler; Anket Formu, Sınav Kaygı Envanteri, Beslenme Alışkanlıkları Ölçeği kullanılarak toplanmıştır. Verilerin analizinde; tanımlayıcı istatistikler, Mann Whitney U, KruskalWallis H, Student t testi, Oneway Anova testi ve Spearman Korelasyon testleri kullanılmıştır.

Bulgular: Araştırmada kız öğrencilerin erkek öğrencilere, üniversite sınavlarına girecek olan 9.-12. Sınıflarda okuyan öğrencilerin lise sınavlarına girecek 5.-8. Sınıf öğrencilerine göre daha fazla sınav kaygısı yaşadıkları saptanmıştır (p
History of the Hematology Proficiency Exam and the Turkish Experience
Authors: BULDUK Tuba , DEMİR Ahmet Muzaffer , ANDIC Neslihan , SAYNALP Nilgün , AYLI Meltem
Published: October 2023

Objective: The purpose of the present paper was to provide information about the Turkish Society of Hematology Proficiency Exam and to raise awareness about continuing medical education and proficiency certification.

Method: The data of the theoretical proficiency exams organized by the Turkish Society of Hematology since 2010 and the participation of Turkish hematologists in the European Hematology Examinations organized since 2017 were evaluated in the study. The number of hematology assistants and specialists who applied for the exam and the success levels of the participants were investigated.

Results: A total of 10 Hematology Proficiency Written Exams have been administered since 2010 and a total of 108 candidates applied for the exam. A total of 53.7% (58 candidates) of the test takers were female and 46.3% (50 candidates) were male. According to the results of the proficiency exam that has been applied since 2010, almost all of the candidates (99%) were successful in the exam. The proficiency oral/practical exam was held for the first time on 29.04.2023.

Conclusion: Proficiency exams are essential to provide an ideal level and standardization in hematology education. When compared to the European Hematology Examination, participation in the proficiency exam is lower than expected in our country. Hematologists should be encouraged to participate in the Hematology Proficiency Exam organized by the Hematology Medical Specialization Qualification Commission (HEM-TUYEK). Hematologists must also be supported to have a certificate of competence, which is an indicator of professionalism and continuous medical education.
Validación de una metodología analítica para la cuantificación de la ciprofloxacina en huevos de gallinas mediante HPLC
Authors: Benítez-Villalba Julio César , Barrios Martiniano , Benítez-Peña Mercedes
Published: October 2023

La ciprofloxacina es un antibiótico del grupo de las fluoroquinolonas utilizadas en medicina humana y veterinaria. Este compuesto posee unas características que hacen que la resistencia de las bacterias a las mismas sea reducida, sin embargo, el amplio uso que ello se utiliza en veterinaria puede propiciar que los residuos de los mismos se incorporen en la cadena alimentaria. Por estas razones, el uso de la mayoría de los antibióticos está regulado por diferentes organismos tanto nacionales como internacionales. En este trabajo de investigación se ha desarrollado y validado una metodología analítica para la determinación y cuantificación de este antibiótico en huevos de gallina que son comercializados en la Gran Asunción. Se ha utilizado la cromatografía de líquidos de alta resolución HPLC- FLD, previamente extracción del analito a partir de la técnica de extracción líquido- líquido. Como columna cromatográfica se utilizó Zorbax C18 (250 mm x 4.5cmm x 5 µm) a una temperatura de 30°C. La detección se realizó con fluorescencia a longitudes de onda de 294 nm (excitación) 500 nm (emisión), empleando una fase móvil de Acetonitrilo: Agua ácido cítrico 50 mM, trietilamina pH 4 (10:90) en modo isocrático. El método analítico ha demostrado ser altamente sensible, con límite de detección inferior a 0,18 µg.g-1. Los resultados comprueban la presencia de este contaminante a concentraciones entre 40.34 y 46.09 µg/Huevo. Los datos obtenidos servirán para sentar un precedente y generar datos de información científica y estadísticamente validadas, que podrá ser útil para dar a conocer a la comunidad científica.
Sonidos sísmicos en Paraguay
Authors: Caballero Alcides , Gadea Moisés , Fugarazzo Rafael , Figueres Vincent
Published: October 2023

Por medio de datos macrosísmicos y de sismicidad histórica, se reporta la ocurrencia de sonidos sísmicos en Paraguay. Estos registros audibles precedieron o acompañaron a los sismos locales según testimonios de pobladores cercanos a los lugares epicentrales.
A new genus record for the flora of Türkiye: Sida L. (Malvaceae)
Authors: Tünk Selin , Koca Aslı , Uygur Sibel , Uygur Feyzullah Nezihi
Published: October 2023

The genus Sida (Malvaceae) is added to Flora of Türkiye firstly here in as a new record genus. The alien weed species Sida spinosa L. was collected from Adana province. The species description supported by detailed photographs is given as well as a scientific name in Turkish for this species was suggested.
Sharing in Their Daily Routines, Joys and Sorrows: Notes from Zambia
Authors: Mrowca Natalia
Published: October 2023

This article is a subjective account of a three-month stay in northern Zambia to carry out research and do volunteer assistance. Written from the perspective of a Polish student of Applied Anthropology, the text shows a gradual change in the Author’s perception of the surrounding new reality, the difficulty of avoiding culture shock, and facing cultural obstacles that, despite preparation, are difficult to be ready for. The main objective, however, is to try to enter the local environment, understand the behaviour, beliefs of Zambians and establish a relationship with the locals. By conducting research on Zambian culture and research on the human flourishing of social life leads, observations are enriched by real conversations with Zambians who open up to the interviewee and enter into a cross-cultural dialogue.
The role of connective tissue metabolism disorders in the genesis of stress urinary incontinence in premenopausal women
Authors: Beniuk V.O. , Puchko M.S. , Drupp Y.H. , Nykoniuk T.R. , Oleshko V.F. , Momot A.A. , Kovaliuk T.V.
Published: October 2023

Research objectives: to study the pathogenetic links in the development of stress urinary incontinence (SUI) by determining the state of connective tissue (CT), concentrations of trace elements, vitamins and estradiol in premenopausal women.Materials and methods. 189 women aged 45–55 years with SUI were examined. In addition to general clinical examination, concentrations of Total PІNP (type I collagen synthesis marker) and Total PІІІNP (type III collagen synthesis marker) and CT resorption marker Pyriliks-D, ionized magnesium, ionized calcium, total calcium, vitamins D and C, estradiol were studied in the blood serum in order to determine the state of fibrous CT.Results. In the structure of somatic morbidity were conditions defined as phenotypic manifestations of CT undifferentiated dysplasia. A decrease of the Total PІNP by 24.9% was found against the background of an increased Total PІІІNP by 46.7% and an increased Pyriliks-D by 54.1%. Women with SUI were characterized by a significant decrease in the average value of Mg2+ by an average of 16.7%, as well as a significant increase in the average value of Ca2+ by 5.3% and total Ca by 3.9%. The vitamin balance study shows a significant decrease of vitamin D by 40.6% and vitamin C by 37.0%. Estradiol concentration was at the minimum values of the physiological norm.Conclusions. Women in premenopausal age with SUI are characterized by a violation of the CT synthesis and resorption, which are realized by reducing the formation of the Total PІNP against the background of intensification of the Total PІІІNP and Pyriliks-D synthesis, combined with a disbalance of vitamins and trace elements. These features are highly likely to be considered as predictors of the SUI development in women of premenopausal age
ПРАКТИЧНЕ ВИКОРИСТАННЯ МОДЕЛІ ОЦІНКИ ЗМІНИ ПАРАМЕТРІВ ОПТОВОЛОКОННОГО СЕРЕДОВИЩА ПЕРЕДАЧІ ДАНИХ
Authors: Погребняк Людмила , Романенко Марія , Болотюк Юлія
Published: October 2023

На сьогодні, для передачі інформації між складовими мереж на основі засобів з вбудованим програмним забезпеченням використовується декілька фізичних середовищ, а саме: радіоканал, оптоволоконні та проводові лінії. В роботі розглядається можливість зміни основних параметрів оптоволоконної лінії від часу експлуатації. При цьому вважається що умови експлуатації цих ліній відповідають умовам встановленим виробниками. У процесі експлуатації, оптоволоконні лінії передачі інформації піддаються різним зовнішнім впливам (нагрів, охолодження, сонячна радіація, механічне та електричне навантаження). Допустима ступінь цих впливів визначається технічною та експлуатаційною документацією і залежать від конструкції оптоволоконних виробів, кліматичного виконання, способу, монтажу та прокладки. Параметрами, які використовуються для оцінки, можуть бути: експлуатаційні (вимірюються штатними приладами без виведення обладнання з експлуатації); параметри технічного стану (вимірюються зовнішнім устаткуванням із зупинкою обладнання, частковим або повним розбиранням). На основі проведеного аналізу існуючих методів оцінки зміни основних параметрів оптоволоконних ліній у часі, поглиблено розглядається один із методів для вирішення завдань технічної діагностики мереж із вбудованим програмним забезпеченням. У своїх працях автори розглядають безконтактний індукційний метод технічної діагностики для об'єкта контролю у вигляді програмно-апаратного комплексу на основі енерго-часового параметра діагностування. Даний параметр дозволяє, без втручання у роботу системи, вимірювати та кількісно оцінювати внутрішні фізико-хімічні процеси старіння складових частин об'єкта контролю. Запропоновані підходи можна застосовувати, у тому числі, для контролю фізичної цілісності об’єкта контролю.
СИНТЕЗ МОДЕЛІ СОЦІАЛЬНИХ САНКЦІЙ ДЛЯ ЗАБЕЗПЕЧЕННЯ СТІЙКОСТІ ВІРТУАЛЬНИХ СПІЛЬНОТ У СОЦІАЛЬНИХ МЕРЕЖАХ В УМОВАХ АНТАГОНІСТИЧНОГО СЕРЕДОВИЩА
Authors: Євсеєв Сергій , Тимонін Юрій , Веретюк Сергій , Войтко Тетяна , Оленюк Дмитро
Published: October 2023

Швидка інтеграція віртуальних комунікацій у суспільне життя актуалізує потребу у створенні безпечного й комфортного середовища для комунікації користувачів віртуальних спільнот. Метою дослідження є підвищення рівня інформаційної безпеки соціальних віртуальних груп шляхом обґрунтування та формалізації особливостей застосування інструментів соціального контролю для управління динамікою віртуальної спільноти в інформаційному просторі. На основі моделей Моно та популяційної динаміки формалізовано процес еволюції віртуальної спільноти в умовах антагоністичного середовища, а також функціонал управління та забезпечення стійкістю віртуальної спільноти в соціальних інтернет-сервісах. Параметрами моделі визначено вплив частки деструктивних публікацій, які становлять загрозу інформаційній безпеці соціальній спільноті; глибина комунікації акторів досліджуваної спільноти з учасниками антагоністичної спільноти; показники якості контенту. У дослідженні набули подальшого розвитку компоненти соціального контролю в соціальних інтернет-сервісах та класифікація порушників інформаційної безпеки.
VOCABULARY OF THE MIDDLE BUG AREA DIALECTS IN THE DIALECT DICTIONARY
Authors: Polishchuk S. S.
Published: October 2023

The article presents a fragment of the “Dictionary of the dialects of the Middle Bug area”. The object of the study is agricultural vocabulary documented in the dialects of the Middle Bug area. The subject of the study is the organization of this lexical layer in the dialect dictionary. The sources of the factual material are audio recordings of vernacular speech with a total duration of 205 hours 54 min. 13 s., made in 74 settlements of the Middle Bug area during the period of 2014–2016.
The article uses general scientific methods of research: analysis, synthesis and observation, which made it possible to identify and systematize the dialect material; the descriptive method was used in the analysis of vernacular speech. Special linguistic research methods: questionnaires and interviews contributed to the documenting of dialect speech, contextual and interpretive analysis allowed to identify transformations of the semantic scope of lexemes functioning in the speech of speakers of the MiddleBug dialects, linguogeographical method made it possible to illustrate the areology of the documented names.
The article describes the structure of a dictionary entry and presents a fragment of the “Dictionary of the dialects of the Middle Bug area”. The register lexemes are marked with letter abbreviations of the names of the examined settlements and with the references to the “Etymological Dictionary of the Ukrainian Language” (1982–2012), the “Eleven-volume Dictionary of the Ukrainian Language” (1970–1980), the “Dictionary of the Ukrainian Language edited by B. D. Hrinchenko” (1907), and the “Dictionary of Ukrainian Dialects of Odesa Region” edited by O. I. Bondar (2011) if the respective word is documented as a dialectism in the above lexicographic sources.
In order to reveal the semantics of a register word and describe in more detail the specifics of the Middle Bug area dialects, sentences and microtexts of dialect speech with the obligatory indication of the settlement where they were recorded have been added. The peculiarities of pronunciation are reflected and illustrative material is presented using the general phonetic transcription for recording Ukrainian literary and dialect speech, which is proposed in the first volume of the “Atlas of the Ukrainian Language”.
The analyzed lexical material emphasizes the originality of the Middle Bug area dialects, as evidenced by pronounced lexical, phonetic and, less often, accentual and grammatical variants of dialect names.
LINGVO-SEMANTIC PALETTE OF THE CONCEPT OF FATE IN THE SLOBOZHANSKY AND BOYKIVSKY DIALECT DISCOURSE
Authors: Minyailo R. V. , Heidel A. M.
Published: October 2023

The anthropocentrism of modern linguistics and the inexhaustibility of the meanings of human existence convince us of the relevance of conceptual analysis. Therefore, the aim of the study was to investigate the linguistic-semantic content of the general cultural concept of FATE in the mental structures of consciousness of the carriers of distant Slobozhansky and Boykivsky dialects, and the task was to structure these semantic units and the corresponding linguistic (speech) constructions. The objects of the study were narrative texts (narratives) of dialect speakers, where the motive of human fate is traced (directly or indirectly), and the subject of the study are the semantic components of the concept of FATE in the Ukrainian dialect continuum and their verbalization at the lexical, phraseological, syntagmatic, and syntactic levels. The methodology of the study consisted of a continuous selection of linguistic-semantic components of the concept of FATE from the dialectological material recorded in the summer of 2021 and a semantic analysis of the identified speech structures.In the analyzed narratives, the concept of FATE is represented by denominations that belong to the lexico-semantic groups (LSG) «Expressions about the inevitability of fate», «Expressions about the hardship of female fate», «A statement about the need to change one’s destiny», «A statement about the typical fate of a representative of a certain community in a certain historical period». In the LSG «Statements about the inevitability of fate» we single out speech constructions that fit into semantic models (SM) «the bureaucratic apparatus of a totalitarian state moves a person from his native place against his wishes», «the dependence of life’s fate on a typical life model»; in LSG «Statements about the hardships of a woman’s fate» − SM: «a stepmother (mother-in-law, fatherin-law) interferes in the formation of a young woman’s life destiny», «the fatalism of an unsuccessful marriage for a woman»; in LSG «Statements regarding the need to change one’s fate» − SM: «satisfaction with one’s fate (aspiration for a sustainable life)», «active position in changing one’s fate», «active position in changing the fate of one’s children»; in LSG «Statement about the typical fate of a representative of a certain community in a certain historical period» − SM: «lack of work and decent earnings as a negative factor in life’s fate», «habituation of representatives of another ethnic group to the search for a better fate in the worlds».We see a comparative analysis of the linguistic and semantic components of the concept of FATE in Ukrainian spoken and artistic discourses as a research perspective.
Realizacja zasady prawdy w postępowaniu cywilnym a ciężar dowodu i ciężar argumentacji
Authors: Krok Michał
Published: October 2023

The purpose of the paper is to analyze, how rules of the burden of proof and rules of the burden of argumentation justify a thesis, which is found as a true statement by court. Two concepts of the truth discussed in the Polish civil procedure (the objective/material truth and the judicial truth) are compared in connection with the rules of the burden of proof and the burden of argumentation. The rules of burden of proof and the rules of the burden of argumentation are constitutive rules. They state under what conditions a thesis counts as justified. The justification of a decision of applying law based on the rules of the burden of proof or rules of the burden of argumentation is institutional, not substantial.
Prawda materialna w procesie karnym w perspektuwie projektowanych zmian kodeksu postępowania karnego
Authors: Przygucki Paweł
Published: October 2023

The aim of the article is to present how the material truth principle will change according to an amendment to the Polish Criminal Procedure Code, which will come into force on 1st January 2015. The amendment reduces an inquisitorial role that court plays under current regulations by transfering a duty of introducing evidence to litigators. In this article there is an attempt to present possible dangers connected with such regulations. Specifically, the major stress was put onto answering the question how the public prosecution would tackle that issue and how it would influence the material truth principle. The author attempted to show that a dispute about making criminal procedure more contradictorial is in fact a conflict between basic principles of criminal trial, which is the material truth priciple. and effectiveness directive.
The basic biology of erbB-2 and its participation in colorectal cancers
Authors: Stawińska Magdalena , Bryś Magdalena , Krajewska Wanda M.
Published: October 2023

ErbB-2 is one of Tour cell surface growth factor receptors involved in transmission of signals controlling normal cell growth and differentiation. A range of growth factors serve as ligands, but none is specific for the ErbB-2 receptor. Ligand binding to ErbB-1, ErbB-3 and ErbB-4 induces rapid receptor dimerization, with a marked preference for ErbB-2 as a dimer partner. When ErbB-2 is overexpressed multiple ErbB-2 heterodimers are formed and cell signalling is stronger, resulting in enhanced responsiveness to growth factors and malignant growth. This explains why ErbB-2 overexpression is an indicator of poor prognosis in colorectal cancers and may be predictive of response to treatment. ErbB-2 is a highly specific and promising target for new colon cancer treatments.
Sexual selection in the Swallow Hirundo rustica - A review
Authors: Bańbura Jerzy
Published: October 2023

Darwinian theory of sexual selection and its development up to the present state of knowledge are sketched. The most important results of empirical studies on sexual selection in the Swallow Hirundo rustica are reviewed. The Swallow is a socially monogamous, slightly sexually dimorphic avian species. Long tail streamers are considered as sexual ornaments of males. Female preference for long and symmetric male tails has been inferred on both observational and experimental grounds. Experimental elongation of the tail causes short-term benefits and long-term costs in male reproductive performance. Behavioural consequences of sexual selection acting in the Swallow are discussed. An aerodynamic role of male tail streamers is also considered.
Mobil Uygulama Destekli Okul Dışı Öğrenme Ortamı
Authors: TURAN GÜNTEPE Ebru , DURUKAN Ümmü Gülsüm , DÖNMEZ USTA Necla
Published: October 2023

Bu araştırmada, öğretmen adaylarının mobil uygulama destekli okul dışı öğrenme ortamlarına yönelik dijital materyaller geliştirmeleri ve bu materyallerin uygulanarak değerlendirilmesi amaçlanmaktadır. Özel durum yöntemi ile gerçekleştirilen bu araştırma, 2020-2021 eğitim-öğretim yılı bahar yarıyılında bir devlet üniversitesinin eğitim fakültesinde öğrenim gören 31 öğretmen adayıyla yürütülmüştür. Veri toplama aracı olarak Materyal Değerlendirme, Bilgi Toplama ve Yansıtıcı Yazı Formları kullanılmıştır. Öğretmen adaylarının Materyal Değerlendirme Formu’ndan aldıkları puanlar betimleyici istatistiksel analizle, Bilgi Toplama Formu ve Yansıtıcı Yazı Formu’ndan elde edilen verilerse içerik analizi yöntemiyle analiz edilmiştir. Araştırmada öğretmen adaylarının tamamı mobil destekli okul dışı öğrenme ortamlarına yönelik materyallerin, öğrenenlerin bilgilerini kalıcı hale getirmeye yardımcı olduğunu, onların derse olan ilgilerini ve motivasyonlarını arttırdığını belirtmişlerdir. Ayrıca öğretmen adayları, bu tür mobil destekli uygulamaları kullanarak öğrenenlerin teknoloji kullanım yeterliliklerinin desteklenebileceğini ve teknolojiyi bilinçli kullanabileceğini de vurgulamaktadır. Araştırma sonucunda, okul dışı öğrenme ortamlarında kullanılabilecek teknoloji destekli benzer mobil uygulamaların geliştirilmesi ve bu uygulamalar kullanılarak öğrenme ortamlarının zenginleştirilmesi önerilmektedir.
Okul Dışı Öğrenme Ortamlarının Öğrencilerin Bilimin Doğası Anlayışlarına Etkisi ve Bu Ortamlar Hakkındaki Görüşleri
Authors: TAYŞİ TAFRACI Sevgi , AYDIN Abdullah
Published: October 2023

Bu araştırmada, 6. sınıf fen bilimleri dersi vücudumuzdaki sistemler ve sağlığı ünitesinin öğretiminde okul dışı öğrenme ortamlarıyla yürütülen etkinliklerin öğrencilerin bilimin doğası anlayışlarına etkisinin araştırılması amaçlanmıştır. Diğer bir amaç ise öğrencilerin ilgili ünite konularını öğrenirken derslerinde yararlandıkları okul dışı öğrenme ortamları hakkındaki görüşlerinin alınmasıdır. Bu amaçlar doğrultusunda, 2021-2022 eğitim-öğretim yılının ikinci döneminde Batı Karadeniz Bölgesi’nde bir ilin ilçesinde bulunan bir devlet ortaokulunda öğrenim gören 32 öğrenci araştırmanın çalışma grubunu oluşturmuştur. Araştırmada, nicel ve nitel araştırma yöntemlerinin bir arada kullanıldığı karma araştırma yönteminin bir çeşidi olan sıralı açıklayıcı desen kullanılmıştır. Araştırmanın nicel verileri, Bilimin Doğasını Anlama Ölçeği ile nitel verileri ise, Yarı Yapılandırılmış Görüşme Formu ile toplanmıştır. Verilerin analizi sonucunda, okul dışı öğrenme ortamlarında yapılan etkinliklerle destekli derslerin işlendiği deney grubu öğrencilerinin bilimin doğası anlayışlarında kontrol grubundaki öğrencilere kıyasla istatistiksel olarak anlamlı bir farklılık tespit edilmiştir. Elde edilen nicel verileri desteklemek amacıyla, deney grubundan seçilen sekiz öğrenciye uygulanan yarı yapılandırılmış görüşme formundan elde edilen verilere göre ise, öğrencilerin çoğunluğu birçok konuyu öğrendiklerini, dersi daha eğlenceli bulduklarını, kavramları öğrenirken zorlanmadıklarını ve okul dışı öğrenme ortamlarında bulunmaktan mutlu olduklarını ifade etmişlerdir. Fen bilimleri öğretmenlerine daha çok okul dışı öğrenme ortamlarından yararlanmaları önerilmektedir.
Frequency and importance of herbal use among presurgical patients: A prospective cohort study
Authors: Turan Cıvraz Ayse Zeynep , Candan Sema
Published: October 2023

Aim: Herbal medicine has been used by humankind since ancient times. However, its popularity has increased in the last 20-30 years. In addition to the production, presentation and marketing of herbal medicines, their effects on the body are also very complex. Uncertainty about the effects of these drugs on the body has increased the importance of pre-anesthetic evaluation. To determine the frequency of herbal drug use in patients presenting for preoperative evaluation and to highlight its importance in anesthetic practice.Method: It was designed as a prospective study with observational-analytical character. Patients over 12 years of age presenting to the Anesthesia Outpatient Clinic of our hospital for pre-anesthetic assessment were interviewed about their use of herbal medicines for 2 months. Patients who used herbal medicines were asked about the medicines they used.Results: A total of 2712 patients were evaluated. Of the patients attending the outpatient clinic, 2367 were over 12 years of age. The use of herbal drugs was found to be 1.18% (n=28). Among the patients who used herbal medicines, 53.6% were female and the mean age was 52.18±15.87 years. The most commonly used herbal medicines were black cumin, green tea, ginger, turmeric, cinnamon, and olive leaf.Conclusions: The use of herbal medicines may be much higher than detected in patients presenting for pre-anesthetic examination. As the effects of herbal products are very uncertain, they may interact with anesthetic drugs. They can prolong bleeding time, increase blood pressure and cause heart problems. For these reasons, they should be closely questioned in the pre-anesthetic examination and discontinued before surgery.
Anesthesia in patients with electrical burn: A retrospective study
Authors: Mehel Asuman , Akdeniz Sevda , Gumus Nevzat , Karacuha Surucu Rumeysa , Secgin Serife , Komurcu Ozgur , Suren Mustafa
Published: October 2023

Aim: We aimed to share our anesthesia experiences with patients hospitalized for electrical burns and underwent surgical intervention under anesthesia in the burn clinic of our hospital.Method: Data gained from our hospital's patient files and medical information system were retrospectively evaluated. The study included patients diagnosed with electrical burns hospitalized in our burn clinic in 2018-2022.Results: The study involved files of a total of 694 patients. Fifty (7.2%) patients were treated for electrical burns. The required data from 3 of the patients could not be accessed, therefore the study was completed including 47 patients. We found that 22 patients did not need surgical treatment. Twenty-five were given anesthesia for different surgical procedures: 20 of those received general anesthesia, while five underwent neuraxiel anesthesia/regional anesthesia. There were no anesthesia-related complications in any patients in the perioperative period.Conclusions: Anesthesia applications should be carefully planned against possible complications in patients with electrical burns.
PENGEMBANGAN APLIKASI KONSULTASI ONLINE DAN JANJI TEMU DOKTER HEWAN BERBASIS ANDROID
Authors: Azaliarahma Salma Aufa , Martyan Elsa Intania , Rahmadani Afsha , Dirgahayu Raden Teduh
Published: October 2023

Pada tahun 2020 di Indonesia hanya terdapat dua puluh ribu dokter hewan dari tujuh puluh ribu dokter hewan yang dibutuhkan. Hal ini menyebabkan persebaran dokter hewan kurang merata di beberapa daerah di Indonesia. Perkembangan teknologi informasi yang pesat dapat diimplementasikan pada bidang kesehatan hewan peliharaan berupa aplikasi konsultasi kesehatan hewan sebagai wadah bagi pemilik hewan dan dokter hewan untuk dapat saling berkomunikasi secara online. Penelitian ini bertujuan mengembangkan aplikasi konsultasi kesehatan hewan dan janji temu dengan dokter hewan secara online berbasis Android yang dinamakan HiVet!. Pengembangan aplikasi menggunakan metode Lean Software Development (LSD) dengan pengujian aplikasi berupa pengujian black box, system usability scale, serta environtment testing. Dari hasil penelitian, dapat disimpulkan bahwa aplikasi HiVet! sebagai wadah yang menjembatani dokter hewan dan pemilik hewan untuk berkomunikasi secara online dapat memudahkan pemilik hewan dalam mengakses fasilitas kesehatan bagi hewan peliharaannya.
Data Privasi dan Keamanan Siber pada Smart-City: Tinjauan Literatur
Authors: Ilhami Dyah Ayu Suci
Published: October 2023

Perkembangan teknologi yang seiring tahun semakin canggih sehingga membuat digitalisasi menjadi perbincangan utama. Tidak kalah utama, maka dari itu sistem dalam sebuah kabupaten maupun kota juga harus digitalisasikan. Smart-city merupakan suatu gerakan yang digencarkan oleh pemerintah dalam rangka mendigitalisasikan kabupaten dengan tentunya infrastruktur – infrastruktur yang seharusnya sudah dimiliki oleh kabupaten atau kota yang menjadi incaran dalam gerakan smart-city. Namun, dikarenakan rancangan ini masih tahap tahapan awal dari 2017, perlu dipertimbangkan beberapa teknologi agar ketika sebuah kabupaten ataupun kota ingin menjadi smart-city tingkat keamanan, privasi data, dll masih terjamin keamanannya. Terdapat beberapa teknologi yang dapat membantu sistem keamanan dan perlindungan data privasi masyarakat ataupun pemerintah, salah satunya menggunakan teknologi IoT arsitektur. Yang mana penerapan IoT arsitektur dalam negara lain sudah memperlihatkan hasil yang cukup memuaskan, sehingga jika di terapkan pada Indonesia yang sedang gencar-gencarnya membuat menjadi smart-city bisa untuk dicoba. Dalam penelitian sudah dijelaskan bagaimana IoT arsitektur dan blockchain mampu melindungi keamanan dan data privasi dan teknologi apa saja yang mampu menyeimbangkan dengan program atau gerakan smart-city ini.
PERANCANGAN UI/UX DESAIN APLIKASI MOBILE TAMAN SAMPAH DESA CEPOGO DENGAN METODE DESIGN THINKING
Authors: Bimantara Adi Wahyu , Paputungan Irving V
Published: October 2023

Taman Sampah atau TAMPAH, merupakan unit usaha BUMDesa Tumang Desa Cepogo Kabupaten Boyolali Jawa Tengah. Tujuan dari pendirian unit usaha Taman Sampah diantaranya untuk mengatasi masalah sampah di Desa Cepogo, memperbaiki pola kebiasaan membuang sampah masyarakat, dan menjaga kelestarian lingkungan. Dalam implementasinya, masih banyak warga masyarakat Desa Cepogo yang belum mengetahui akan fungsi atau keberadaan unit usaha Taman Sampah tersebut. Dengan demikian dibutuhkan gagasan atau inovasi yang lebih, agar masyarakat dapat mengetahui tujuan akan unit usaha TAMPAH tersebut. Penelitian ini bertujuan untuk mengimplementasikan terkait perancangan user experience pada user interface desain aplikasi mobile Taman Sampah atau TAMPAH dengan metode design thinking. Beberapa tahapan yang dilakukan dengan metode design thinking, meliputi empathize, define, ideate, prototype, dan testing. Dalam penelitian ini, diharapkan dapat membantu masyarakat dalam memberikan inovasi terkait rancangan desain aplikasi TAMPAH yang bertujuan sebagai upaya pengelolaan sampah dan mengurangi sampah yang ada di Desa Cepogo.
Only in Natural Spacetime Does Nature Disclose Her Secrets
Authors: Niemz Markolf H.
Published: October 2023

Special (SR) and general relativity (GR) describe nature subjectively. Mathematically, their equations are correct. Here I show: (1) Physically, both SR and GR have an issue. Spacetime in either theory is not natural, but construed by observers. Rulers and clocks measure proper distance di and proper time τ. They are not aware of coordinate space x1, x2, x3 and coordinate time t in SR. They are also not aware of the xi that an observer uses to parameterize spacetime in GR. Thus, rulers and clocks are not able to measure what is calculated in SR/GR. Still, the Lorentz factor and gravitational time dilation are correct. This is why SR/GR work so well in an observer’s reality. (2) Euclidean relativity (ER) describes nature objectively. In ER, proper space d1, d2, d3 and proper time τ of any (!) object span “natural spacetime”, which is 4D Euclidean space (ES) if we set cτ = d4. All energy is moving through ES at the speed of light c. Each observer’s reality is created by projecting ES orthogonally to his proper space and to his proper time. These axes are reassembled in SR/GR to a non-Euclidean spacetime. But the SO(4) symmetry of ES is not compatible with waves. This is fine because waves are observer-related features: What I deem wave, deems itself matter. We must learn to distinguish between an observer’s reality (with waves) and the master reality (without waves). SR/GR describe an observer’s reality. ER describes the master reality. ER improves our understanding of cosmology and quantum mechanics: It solves the Hubble tension, dark energy, and non-locality.
On the Origin Debate and Plausible Future Endeavours of COVID-19 (Commentary)
Authors: Nandy Debdatta , Chatterjee Bijit , Basu Sankar
Published: October 2023

Globally, we are undergoing compelling changes in virtually every branch of the society and every aspect of our daily lives over the last couple of years due to the COVID-19 pandemic. In the words of Melinda Gates, the famous American Philanthropist, the pandemic has literally “magnified every existing inequality”. There has been much talk and an ongoing debate on the origin of SARS-CoV-2 (or, the novel coronavirus) as to whether have evolved purely naturally or has the contaminating element of human intervention somewhere in its trajectory. Proponents of the pure ‘natural evolution theory’, some of whom are bigshots in the field of virology have seem to take up great effort to stamp their authority right from the very early days of the pandemic on the slow natural evolution of the virus from its ancestrors by several publications in high-profile journals. These well-cited papers however provide rationals that are somewhat contradictory and are backed up with data which maybe argued as far from being complete and/or all-inclusive. As time progressed, alternative theories to that of the pure natural evolution of the virus emerged with strong counter-logics and gradually compiling genomic and epidemiological data along with detailed structural studies of relevant molecular interactions. All said and done, till date, compelling evidences lack on either end of the spectrum making the COVID origin debate still very mucg wide open. Regardless of whether purely natural or human-intervented the damage caused by the virus is unmistakable and has been an alarming concern to medical science lately. To that end, a section of the scientific community is devoting committed efforts using immuno-informatics to design and develop possible multi-epitope combination vaccines to cover a plethora of viral antigens and their plausible future mutations, alongside with the vaccines that are currently available.
Bone Health in the Transgender Population
Authors: Goodrich Ezra , Walcott Quinnlyn , Dallman Johnathan , Crow Hanna , Templeton Kimberly
Published: October 2023

» Transgender women are more susceptible to low bone mineral density (BMD) before initiating gender-affirming hormone therapy (GAHT), and while bone density initially improves with GAHT, it gradually declines while still remaining above baseline. Transgender women older than 50 years have a comparable fracture risk as age-matched cisgender women. Transgender men typically have normal or increased BMD before initiating and while receiving GAHT and are not at increased risk of fractures.

» Transgender youth who receive puberty-blocking medications experience either no change or a slight decrease in BMD that returns to baseline after initiating GAHT.

» It is important to abide by the International Society for Clinical Densitometry guidelines whenever ordering, performing, or reading a BMD scan for a gender-diverse patient.

» There are no specific guidelines concerning vitamin D and calcium supplementation or the use of bisphosphonates in the transgender population, so the current recommendation is to abide by the guidelines for cisgender individuals.
Mineral Scaling Impact on Petrophysical Properties of Reservoir Rock in a Geothermal Field Located in Northwestern Iran
Authors: Zolfagharroshan Mohammad , Khamehchi Ehsan
Published: October 2023

As the usage of geothermal energy as a zero-emission power resource continues to grow in significance, comprehending the interplay between physical and chemical processes within geothermal reservoirs becomes crucial. In this study, a computationally efficient fluid flow and heat transfer model, combined with a fluid chemistry model, is used to simulate fluid circulation and mineral precipitation in reservoir rock, resulting in changes in rock porosity and permeability. A 2D hybrid approach is employed to solve transient mass and momentum conservation equations, coupled with an analytical solution of the energy equation proposed in the literature for geological formations. A marching algorithm is utilized to calculate velocity and temperature fields in the axial direction within the production zone. Mineral scaling is addressed using the outputs of the hybrid model to perform saturation index (SI) and solution/dissolution computations for qualitative and quantitative mineral precipitation modeling. Multiple criteria are considered to assess the likelihood and intensity of fouling issues. The analysis results are used in an empirical model to estimate rock secondary porosity and permeability changes over a 5-year period of heat extraction. The developed simulator is applied to model a site in the Sabalan geothermal field in Iran, and its initial verification is conducted using data from the same site in the literature. The findings in the study for a sensitivity on fluid circulation rate reveal that increasing water circulation flow rate increases precipitation rate and pumping power required. Furthermore, even minor instances of pore blockage can result in notable reductions in permeability. Consequently, ensuring precise control over pressure and temperature during the production phase becomes progressively crucial for both reservoir integrity and production assurance. The proposed framework provides a promising approach for accurate and efficient simulation of geothermal reservoirs to optimize power generation and minimize environmental impact.
Investigating the Design Parameters and Simulation of a Piezo-actuated Vibratory Micro-robot in Hybrid Motion
Authors: Jalili Hadi , salarieh hassan , Vossoughi Gholamreza
Published: October 2023

In this paper, a complete dynamics model of a vibratory micro-robot has been investigated by considering both the dynamics of actuators and jump phenomena. The actuators of this micro-robot are piezo-electric. The main motion mechanism of this micro-robot is based on the principle of the friction drive. But due to the nature of piezo-electric actuators (high frequency), situations sometimes occur where the micro-robot encounters the phenomenon of jumping, and the principle of the friction drive no longer applies. Combining the principle of friction drive with the phenomenon of jumping creates a hybrid dynamic motion, which is called the principle of stick-slip-jump. Modeling and motion simulation based on this principle, adding the dynamic model of piezo-electric actuators, are very complicated, especially when the micro-robot impacts moving substrate. In this research, along with complete modeling of the micro-robot in stick-slip-jump motion and extracting the effective design parameters, the ability to model this complex dynamic for the exact simulation of the micro-robot's behavior has been verified experimentally.
Effects of Partnership Status and Social Determinants of Health on Total Testosterone Levels in a Large Cohort of American Men
Authors: Shyr William , Jun Grace , Davila Jonathan
Published: October 2023

This study aims to investigate the interplay between biological and non-biological factors and their effects on total testosterone (TT) levels in men. This is a retrospective cross-sectional study based on the National Health and Nutrition Examination Survey (NHANES) program designed to investigate the social and biological factors that affect TT levels in adult men in the United States. Data were obtained from the 2011–2016 NHANES survey study. We examined the effect of partnership status, family income-to-poverty ratio (PIR), education, tobacco use, diabetes mellitus (DM), coronary artery disease (CAD), hypercholesterolemia, hypertension, age, and body mass index (BMI) on TT levels. Our final cohort included 7,168 men aged 18 to 79. In the multiple linear regression analysis, cohabitation and being Non-Hispanic Asian had the largest negative effect sizes (-34 [95%CI: -45 - -23] and − 40 [95%CI: -55 - -27]) on TT compared to those of BMI (p < 0.001) and hypercholesterolemia (p < 0.001), but the effect of PIR was not significant. This study suggests that living with a partner is one of the strongest predictors of lower testosterone in men.
Unlocking wide-bandwidth and high-efficiency: topological slow-light structure for electro-optic modulation
Authors: Zhang Yong , Shen Jian , Zhang Lei , Li Jingchi , Feng Chenglong , Jiang Yongheng , Wang Hong-Wei , Li Xingfeng , He Yu , Ji Xingchen , Tian Yonghui , Xiao Xi , Chen Haoshuo , Fontaine Nicolas , Ren Guanghui , Mitchell Arnan , Su Yikai
Published: October 2023

High-speed electro-optic modulators are key components in modern communication networks and various applications that require chip-scale modulation with large bandwidth, high modulation efficiency, and compact footprint. However, fundamental trade-offs make it challenging to achieve these metrics simultaneously, and thus new methodologies must be explored. To this end, we present the first demonstration of a Mach-Zehnder modulator harnessing topological slow-light waveguides and capacitively loaded slow-wave electrodes on silicon-nitride-loaded lithium niobate on an insulator platform. Owing to the slow-light effect in the one-dimensional topological waveguide, the increased light-matter interaction time and group index significantly improve the modulation efficiency. With the 1-mm-length modulation section, a record low half-wave voltage length product Vπ∙L of 0.21 V∙cm is obtained, which is one order of magnitude smaller than that of conventional thin film lithium niobate Mach-Zehnder modulators. Slow-wave electrodes are employed for electro-optic velocity and impedance matching, enabling an unprecedented bandwidth of 110 GHz without roll-off. The achieved bandwidth-efficiency ratio of 524 GHz/V/cm is among the highest reported for all-dielectric and semiconductor modulators. Four- and eight-level pulse amplitude modulation signals of up to 240 and 300 Gbps, respectively, have been generated using the topological modulator. Our topological modulator provides ultra-large bandwidth, ultra-high efficiency, and a compact solution for next-generation electro-optic systems.
The FRESHAIR4Life study: Global implementation research on non-communicable disease prevention targeting adolescents’ exposure to tobacco and air pollution in disadvantaged populations
Authors: Hoffman Charlotte , Versluis Anke , Chirila Sergiu , Kirenga Bruce , Khan Amina , Saeed Saima , Sooronbaev Talant , Tsiligianni Ioanna , Arvind DK , Bauld Linda , Brand Floor van den , Chavannes Niels , Pinnock Hilary , Powell Pippa , Schans Jurjen van der , Siddiqi Kamran , Williams Siân , Kleij Rianne van der
Published: October 2023

In the FRESHAIR4Life study, we aim to reduce the non-communicable disease (NCD) burden by implementing preventive interventions targeting adolescents’ exposure to tobacco use and air pollution (AP). This paper presents the methodology of FRESHAIR4Life and initial rapid review results.
The rapid review showed variable NCD mortality rates related to tobacco use and AP exposure in the five participating countries. Tobacco is the predominant risk factor for NCD-related deaths in the Kyrgyz Republic, Greece, and Romania, whereas AP exposure causes most NCD-related deaths in Pakistan and Uganda. Adolescents’ risk factor exposure, sources of exposure, and trends also differ significantly.
As the next step in FRESHAIR4Life, an in-depth situational analysis will inform the selection, adaptation, and integration of evidence-based interventions into the FRESHAIR4Life prevention package. Subsequently, this package will be implemented, evaluated, and iteratively refined. Throughout the research process, a strong emphasis is on co-creation, capacity building, and comprehensive communication and dissemination.