bluuebunny/crossref_metadata_2025 huggingface dataset:
Minimum-time lane changing problem of vehicle handling inverse dynamics based on adaptive mesh refinement and collocation optimization method
Authors: Liu Yingjie , Cui Dawei , Peng Wen
Published: August 2023

In order to solve the problems of multiple constraints, many different calculations of nonlinear equations which lead to major errors in the process of vehicle lane changing with minimum time, an adaptive mesh refinement and collocation optimization method is proposed. Firstly, the problem of vehicle lane changing with minimum time has been divided into nonlinear programming problems in different grids. The Lagrange interpolation polynomial was used to approximate the solution of the optimization problem in the grid, and the absolute and relative errors were resolved. Then, a mesh was determined for the unsmooth part according to the curvature of the trajectory, and the location and number of meshes were further determined according to the relationship between the maximum relative error and the allowable error. At the same time, the solution accuracy was improved by adding an adaptive calculation to the smooth interval which does not meet the tolerance error. Finally, the simulation example of comparison with the traditional optimization method was proposed. The results showed that the algorithm presented in the paper had a higher solution efficiency under the same calculation accuracy.
Drinking water quality management progress in Ontario, two decades after Walkerton
Authors: Fuller Megan , Wells Emma , Furatian Laith , Douglas Ian , Lane Kaycie
Published: August 2023

Following the waterborne disease outbreak in Walkerton, Ontario, the province made significant efforts to implement recommendations of the public inquiry that resulted. As Ontario reformed its drinking water sector, other jurisdictions were advancing risk-based quality management frameworks for drinking water, including the World Health Organization (WHO) through its water safety plan (WSP) framework. Two decades after the Walkerton tragedy, this paper seeks to: (i) evaluate alignment of Ontario's Drinking Water Quality Management Standard (DWQMS) with the WSP framework (ii) review readily available data for evidence that Ontario's DWQMS implementation has improved drinking water safety and promoted a preventive approach through risk-based quality management. Our study found strong alignment between the Ontario DWQMS and WSP frameworks, with supporting programmes and risk assessment procedures present. Analysis of available regulatory data revealed abundant reporting of water quality and adverse incidents in municipal water systems. However, performance data were publicly available, the use of percentage scores for water quality testing obscures the details of system performance and water safety. Reports describing the DWQMS plan and audit results were difficult to obtain and not standardized. There is a need to develop mechanisms to ensure continual improvement of the DWQMS.
Hybrid model for daily streamflow and phosphorus load prediction
Authors: Lee DoYeon , Shin Jihoon , Kim TaeHo , Lee Sangchul , Kim Dongho , Park Yeonjeong , Cha YoonKyung
Published: August 2023

Environmental factors, such as climate change and land use changes, affect water quality drastically. To consider these, various predictive models, both process-based and data-driven, have been used. However, each model has distinct limitations. In this study, a hybrid model combining the soil and water assessment tool and the reverse time attention mechanism (SWAT–RETAIN) was proposed for predicting daily streamflow and total phosphorus (TP) load of a watershed. SWAT–RETAIN was applied to Hwangryong River, South Korea. The hybrid model uses the SWAT output as input data for the RETAIN. Spatial, meteorological, and hydrological data were collected to develop the SWAT to generate high temporal resolution data. RETAIN facilitated effective simultaneous prediction. The SWAT–RETAIN exhibited high accuracy in predicting streamflow (Nash–Sutcliffe efficiency (NSE): 0.45, root mean square error (RMSE): 27.74, percent bias (PBIAS): 22.63 for test sets), and TP load (NSE: 0.50, RMSE: 423.93, PBIAS: 22.09 for test sets). This result was evident in the performance evaluation using flow duration and load duration curves. The SWAT–RETAIN provides enhanced temporal resolution and performance, enabling the simultaneous prediction of multiple variables. It can be applied to predict various water quality variables in larger watersheds.
EL CONTROL NATURAL DE Stenoma catenifer WALSIMGHAM EN EL CULTIVO DEL PALTO Persea americana MILL. EN CHANCHAMAYO, PERÚ
Authors: Arellano Cruz Germán , Vergara Cobian Clorinda
Published: August 2023

El cultivo del palto (Persea americana Mill.) tuvo mucha importancia en Chanchamayo y Satipo hasta 1982, aportando el 47% de la producción nacional, y fue afectado por "podredumbre radicular" causada por el hongo Phytophthora cinnamomi Rands. Sobre la base de las evaluaciones realizadas entre los años 1983 y 1987 por los autores, se ha elaborado el presente trabajo actualizando la información al presente en la zona. El objetivo es demostrar que el “barrenador del fruto del palto” Stenoma catenifer Walsimgham se mantuvo como plaga potencial debido a la existencia de un control natural por parasitoides nativos. El método fue registro de la abundancia, importancia, daños, hospedadores alternos y enemigos naturales asociados; basado en recolecciones periódicas mensuales de insectos en las plantaciones de palto y en la vegetación herbácea del cultivo y crianza en laboratorio, registrando las especies plaga e insectos controladores naturales. Se concluye que esta plaga S. catenifer presentó diferentes grados de preferencia por frutos según los cultivares evaluados y dos especies de parasitoides que alternaron sus abundancias durante la campaña. Estos parasitoides mantuvieron un control biológico de ± 70% en los frutos de palto, y los agricultores no se vieron afectados económicamente. Por ello, se podría considerar a esta especie como plaga potencial.
Pre-clinical Evidence-based Neuroprotective Potential of Naringin against
Alzheimer’s Disease-like Pathology: A Comprehensive Review
Authors: Singh Ashini , Kumar Singh Niraj
Published: August 2023

Neurodegenerative disorders (NDs) are a group of progressive, chronic, and disabling
disorders that are highly prevalent and the incidence is on a constant rise globally. Alzheimer’s
disease (AD), one of the most common neurodegenerative disorders is hallmarked by cognitive
impairment, amyloid-β (Aβ) deposition, hyperphosphorylation of tau protein, cholinergic dysfunction,
mitochondrial toxicity, and neurodegeneration. Available therapeutic agents only provide
symptomatic relief and their use are limited due to serious side effects. Recent research has recognized
flavonoids as potential multi-target biomolecules that can reduce the pathogenesis of AD.
Naringin, a natural citrus flavonoid has been traditionally used to treat various NDs including AD,
and has gained special attention because exhibits a neuroprotective effect by affecting numerous
signaling pathways with minimum adverse effects. Naringin reduces deposition of Aβ, hyperphosphorylation
of tau protein, cholinergic dysfunction, oxidative stress burden, mitochondrial toxicity,
the activity of glutamate receptors, and apoptosis of the neuronal cells. Additionally, it reduces the
expression of phosphorylated-P38/P38 and the NF-κB signaling pathway, showing that a wide
range of molecular targets is involved in naringin's neuroprotective action. The present study describes
the possible pharmacological targets, signaling pathways, and molecular mechanisms of
naringin involved in neuroprotection against AD-like pathology. Based on the above pre-clinical
reports it can be concluded that naringin could be an alternative therapeutic agent for the management
of AD-like manifestation. Thus, there is a strong recommendation to perform more preclinical
and clinical studies to develop naringin as a novel molecule that could be a multi-target drug to
counteract AD.
Development of Oral Bio-banks Past, Present and Future; Challenges and
Opportunities
Authors: Hiremath Gangadhar Baniekal , Omkarbabu Kondragunta , Kokate Madhavi Hemant , Venkidasamy Baskar , Krishnan Murugesan , Murugaiyan Arun
Published: August 2023

Biobank involves collecting, processing, storing, and organizing biosamples, along with
relevant personal and health information such as medical history, family records, genetics data, and
lifestyle details, for medical research and clinical care. Oral biobanking is a recently evolved field
alongside the rising of precision medicine due to recent research findings in oral oncology and other
oral complaints, namely caries and periodontal disease. The common samples in oral biobanks are matured
and primary teeth, dental pulp cells, oral biopsies, oral rinses, saliva, and swabs from the buccal
region. Moreover, biobank should not conceive of as a static collection of samples and data but as a
dynamic resource for developing novel techniques that meet current scientific demands through international
networking. However, the major bottlenecks associated with oral biobanks are privacy, processing
of samples, normalization of data, extended durability of interest markers of banked samples,
and financial sustainability of biobanks. Thus in this correspondence, we argue that an alternative approach
is urgently needed to protect the interests of many stakeholders.
Selenium, Selenoproteins and 10-year Cardiovascular Risk: Results from
the ATTICA Study
Authors: Detopoulou Paraskevi , Letsiou Sophia , Nomikos Tzortzis , Karagiannis Alexandros , Pergantis Spiros A. , Pitsavos Christos , Panagiotakos Demosthenes B. , Antonopoulou Smaragdi
Published: August 2023

Background:

Selenium (Se) is an essential trace element that is involved in several pathophysiological
functions. The relationship of Se with cardiovascular disease remains inconclusive, especially
regarding the role of different selenospecies.

Objective:

The present study assessed the levels of Se distribution in plasma selenoproteins, namely
glutathione peroxidase 3 (GPx3), selenoprotein P (SelP) and selenoalbumin (SeAlb) and total Se in
selenoproteins in relation to 10-year cardiovascular risk in the ATTICA prospective study.

Methods:

A sub-sample from the ATTICA Study’s database, consisting of 278 subjects (114 women
and 164 men) with data on Se and selenoproteins levels, was considered. SeGPx3, SelP, and SeAlb in
human plasma were simultaneously determined by high-performance liquid chromatography (HPLC)
coupled with inductively coupled plasma mass spectrometry (ICP-MS) at baseline. The duration of the
follow-up was 8.74 ±2.36 years (mean± standard deviation) and cardiovascular outcomes were recorded.
Cox proportional hazards models were applied with total Se or selenoprotein Se as independent variables
adjusted for several covariates.

Results:

Total Se in selenoproteins was positively related to 10-year relative risk of cardiovascular disease
(Hazard Ratios of 3rd vs 2nd tertile 10.02, 95% CI:1.15, 92.34). Subjects with high Se but low
SeGPx3, as identified by discordant percentiles in the distribution of SeGPx3 and Se, had a higher cardiovascular
risk.

Conclusions:

The differentiated effects of circulating selenoproteins on cardiovascular disease risk in the
present study, suggest the importance of redox regulation by specific selenoproteins.
Review on Pyrazole Hybrids as Anti-microbial Agents
Authors: Goel Tanvi , Jain Naman , Bansode Deepali
Published: August 2023

A five-membered heteroaromatic ring with two nitrogen atoms, pyrazole, is of immense
significance. Pyrazole and its derivatives are well-known nitrogen-containing heterocyclic compounds
that are significant in medicinal chemistry and have a variety of biological properties, according to a
thorough analysis of this class of heterocyclic lead. This article summarises some biologically active,
potent pyrazole hybrids and their structure-activity relationship for antimicrobial activity published by
various researchers across the world. It is divided into two sections. The first part summarizes recent
developments in pyrazole derivatives for various biological activities, such as anti-Alzheimer’s, antioxidant,
anticancer, anti-inflammatory, and antiviral, while the second section focuses on a detailed
substitution analysis of pyrazole with its hybrid, which is the structure-activity relationship needed for
antimicrobial activity. The presence of pharmacological potential of pyrazole moiety has been demonstrated
by the role of a nucleus in pharmacological agents from different therapeutic groups, such as
the potent anti-inflammatory agent celecoxib, anti-obesity drug rimonabant, analgesic diphenamizole,
H2-receptor agonist betazole, and antidepressant agent fezolamide. The design of new pyrazole derivatives
has become an interesting research area due to their versatile nature and biological significance.
Moreover, it has been observed that pyrazole in combination with another moiety has a strong potent
antimicrobial effect.
In vitro and In silico Antibacterial Evaluation of N-Methyl-2-phenylmaleimides
Authors: Fourie Carla , Bezuidenhout Johannes Jacobus , Petzer Anél , Petzer Jacobus Petrus , Cloete Theunis Theodorus
Published: August 2023

Background:

Novel antibiotics are needed to stem the rise of antimicrobial resistance. N-Methyl-2-phenylmaleimide (NMP) compounds previously synthesised by our research group are structural analogues of 2,3,5-substituted perhydropyrrolo[3,4-d]isoxazole-4,6-diones found by others to have antibacterial activity.

Objectives:

This study aims to explain the significance of NMPs and their antibacterial activity. The antibacterial activity of the NMPs was determined against Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa. The partition coefficient of the NMPs and a pharmacophore model were used to explain their antibacterial activity.

Methods:

The Kirby Bauer Disc diffusion method was used to screen the NMPs for activity, while the broth microdilution method was used to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the active NMPs. Using the in vitro antibacterial activity of 2,3,5-substituted perhydropyrrolo[3,4-d]isoxazole-4,6-diones, a common feature pharmacophore model was constructed and validated. The rank score, fit value, enrichment factor (EF20%), and receiver operating characteristic area under the curve (ROC-AUC) were used as validation metrics.

Results:

The NMPs were only active against S. aureus, with compound 3 (4 µg/ml) being the most active. The majority of NMPs were bacteriostatic. A common feature pharmacophore model was validated (rank score: 120.5; fit value: 4; EF20%: 4.3; ROC-AUC: 0.9 ± 0.03) and showed that three hydrogen bond acceptors and a ring aromatic region are important for activity. Comparing the partition coefficient of the NMPs to their MIC a statistically significant correlation was found.

Conclusion:

NMPs can be used as lead compounds in future studies. The validated pharmacophore model and partition coefficient can be used to develop more active compounds.
Interplay of miRNA-TF-Gene Through a Novel Six-node Feed-forward
Loop Identified Inflammatory Genes as Key Regulators in Type-2 Diabetes
Authors: Bhat Gayathri Shama , Keshav Tarakad Ranganatha , Hariharapura Raghu Chandrashekar , Fayaz Shaik Mahammad Abdul
Published: August 2023

Background:

Intricacy in the pathological processes of type 2 diabetes (T2D) invites a need
to understand gene regulation at the systems level. However, deciphering the complex gene modulation
requires regulatory network construction,

Objective:

The study aims to construct a six-node feed-forward loop (FFL) to analyze all the diverse
inter- and intra- interactions between microRNAs (miRNA) and transcription factors (TF) involved in
gene regulation.

Methods:

The study included 644 genes, 64 TF, and 448 miRNA. A cumulative hypergeometric test
was employed to identify the significant miRNA-miRNA and miRNA-TF interaction pairs. In addition,
experimentally proven TF-TF pairs were incorporated for the first time in the regulatory network to
discern gene regulation. The networks were analyzed to identify crucial genes involved in T2D.
Following this, gene ontology was predicted to recognize the biological function that is crucial in T2D.

Results:

In T2D, the lowest gene regulation for a composite FFL occurs through a four-node FFL
variant1 (TF- miRNA-miRNA-Gene, n=14) and the highest regulation via a five-node FFL variant2
(TF-TF-miRNA-Gene, n=353). However, the maximum gene regulation occurs via six-node miRNA
FFL (miRNA-miRNA-TF-TF-gene-gene, n=23987). Subnetworks derived from the six-node miRNATF-
gene regulatory networks identified interactions among TP53 and NFkB, hsa-miR-125-5p and hsamiR-
155-5p.

Conclusion:

The core regulation occurs through TP53, NFkB, hsa-miR-125-5p, and hsa-miR-155-5p
FFL implicating the association of inflammation in the pathogenesis of T2D, which occurs majorly via
six-node miRNA FFL. Thus regulatory network provides broader insights into the pathogenesis of T2D
and can be extended to study the inflammatory mechanisms in various infections.
Rheology Assessment of Mortar Materials for Additive Manufacturing
Authors: Pedrosa Ana , Gaspar Florindo
Published: August 2023

This review article discusses the relevant rheological tests to evaluate the properties of
compositions applied to the 3D printing of concrete (3DCP). These materials must rapidly develop
rigidity and resistance, avoiding the collapse of the printed structure, with suitable buildability
and other state properties, such as extrudability. A good balance must be maintained between
properties and rheological parameters, such as yield stress and viscosity. Cohesion, Young's
modulus, and thixotropy are also among the parameters used in these evaluations. The rheological
tests addressed are the rheometer, direct shear test, uniaxial unconfined compression test, and
penetration test. Their limitations must be taken into account to obtain accurate values of the rheological
parameters. It was found that the most used test is the rheometer, and the test that needs
to be further studied is the penetration test. Hence, it is recommended to search for a more expeditious
method related to the rheological assessment to facilitate obtaining the associated parameters
in a simple way.
Mucormycosis: A Serious Catastrophe Involving COVID-19 Patients
Authors: Dangi Neha , Mehendiratta Himanshu , Sharma Shikha
Published: August 2023

With the global pandemic, COVID-19, spurred on by the "Severe Acute Respiratory Syndrome
Corona Virus-2 (SARS-CoV-2)," India has been greatly impacted. With a rare fungus known as Mucormycosis,
the second wave of COVID-19 significantly impacted the Indian population after the initial
phase. Mucormycosis is also known as "black fungus" because of the necrosis of infected skin tissue,
which causes it to become black. It is caused by Mucoromycetes, members of the Zygomycetes order and
the Mucorales class. COVID-19's effects on various comorbid ailments, such as diabetes, heart problems,
and immune-compromised states, range from mild to severe to life-threatening. Mucormycosis moulds
are more likely to affect patients who have hyperglycemia, ketoacidosis, solid organ or bone marrow
transplantation, liver cirrhosis, or neutropenia. To eliminate Mucormycosis, four primary variables must
be addressed: early diagnosis, eradication of predisposing factors, prompt antifungal treatment with surgical
removal of all diseased tissues, and adjuvant therapies. Here, the present review discusses the clinical
aetiology, symptoms, diagnosis, and therapy for black fungus. The study leads to the conclusion that the
use of immunosuppressant medication to combat COVID-19 also elevates the possibility of being infected
with mucormycotic.
Evaluation of Project Work in a Public Service Building in East Java
Authors:   Universitas Brawijaya, Kurniawan Andhika Dwi , Rachmansyah Arief ,   Universitas Brawijaya, Devia Yatnanta Padma ,   Universitas Brawijaya
Published: August 2023

In the process of implementing a project, few people find projects that go according to plan. In general, there are projects that are behind schedule, both in terms of time and schedule, but there are also projects that experience acceleration from the originally planned schedule. Project delay is a problem that arises as a result of unplanned construction implementation. Damage to the state due to additional costs and delays is one of the impacts of project delays. The purpose of this research is to track project implementation, identify factors that cause delays, calculate the cost of delays that occur, find root causes and suggest alternative solutions that can be used to anticipate project delays. Monitoring and evaluating delays require an approach that includes the use of Microsoft Project Tracking, Fishbone Charts, and Root Cause Analysis. Alternative methods are used to track performance and analyze delays in public service building projects. The results showed a lack of understanding of human resources in terms of planning/evaluating existing plans, lack of training programs related to the field of work being handled, and poor schedule planning causing a lack of lightning rods, installation in the main building, lighting in changing rooms, grounding systems, central duct/airline, less power cables than needed and original water source using PAM water converted into deep pumping wells.
Measuring Resilience of a Tourism Village Against Flash Flood Disaster
Authors: Usman Fadly , Hariyani Septiana , Kurniawan Eddi , Sari Indah
Published: August 2023

One of the most popular tourist destinations in East Java is Batu City, which had been visited by 2.4 million tourists in 2021 during the pandemic, regardless of the fact that 7.2 million tourists normally have visited the city annually before the outbreak. Flash floods that struck Batu City in November 2021 resulted in significant damage and losses which affected several tourism villages. The preparedness of Batu City for potential natural catastrophes was identified throughout this study. It is essential to think of both technological and non-technical ways as preventive measures before a tragedy arises, given how eager travelers are to visit Batu City. Several city-scale analyses are conducted, notably by doing spatial analysis with the use of GIS technology in order to understand land use and probable flow routes. A livelihood asset analysis was used as a methodological and indicator assessment of disaster preparedness in one of the Resilient Village (Destana). The findings indicate that land conversion in production and protected forest areas change into agricultural areas is one factor that triggers flash floods. After a ten-year decline, only 20% of the forest stands are left in hilly and steep terrain, with the rest being farmland and human settlements. Meanwhile, an assessment of the community preparedness in the Tourism Village reveals that the community has a strong capability in terms of financial, social, and natural capital.
Application of artificial intelligence technologies in HR management
Authors: Okladnikova S. V. , Pankrashov A. S.
Published: August 2023

Objective. The purpose of the study is to analyze the possibility of using AI technologies to solve problems related to the selection of employees in project teams, based on production indicators and HR metrics of personnel.Method. Based on the fact that in the field of AI, methods mean algorithms by which tasks are solved, the following number of methods related to AI theory were identified: neural networks, fuzzy logic, expert systems, evolutionary modeling, Machine Learning.Result. An example of the use of AI is given in a situation where it is necessary to recruit personnel for a project based on the length of service and the degree of workload (where a scale with values from “highly loaded” to “not loaded” is used for workload). For the described example, an explanation is given that reveals the use of AI technologies (such as question-and-answer systems) in order to form HR metrics and production indicators. Additionally, the process of applying the objective function to obtain a numerical coefficient based on individual metrics or a combination of them is described in order to make a decision corresponding to its value based on the resulting indicator of the function.Conclusion. Within the framework of the conducted research, the historical patterns that led the field of personnel management to transformation and which made the use of AI technologies relevant in this area were considered. Continuous development and implementation of intelligent tools in the practice of project management facilitates HR processes and increases the efficiency of employee management. The use of AI technologies considered in the study will help to successfully monitor the state of both the project and the project team, which will have a positive impact on the productivity and profit of the enterprise.
Statement of the problem modeling the process vacuum microwave drying for determining temperature fields in foamed suspensions
Authors: Tkach V. V. , Magomedov G. O. , Shevtsov A. A.
Published: August 2023

Objective. The aim of the study is to formulate a mathematical model of the process of vacuum microwave drying to determine the temperature fields in foamed suspensions. With the obvious advantages of microwave drying in a vacuum, the possibility of overheating of the dried material is not excluded, which affects its quality. Therefore, the limitation on the temperature of the material during drying must be taken into account in the simulation.Method. The study is based on the methods of simulation computer modeling.Result. The formulation of the modeling problem for determining the temperature fields in foamed suspensions in a wide range of regime parameters is proposed.Conclusion. Increasing the accuracy of simulation results by improving the mathematical description is the basis of modern research in the field of technology and equipment for vacuum microwave drying.
Vibration of a Beam with Concentrated Masses on Elastically Damping Supports
Authors: Kaziev A. M. , Kishit I. I. , Zhinov A. M. , Karchaev K. M. , Berbekov A. A.
Published: August 2023

Objective. The aim of the study is to study the operation of multi-span beams with point masses under the simultaneous action of vector kinematic and force loads. Taking into account the influence of elastic-damping supports.Method. The study is based on the solution of the boundary value problem and modeling.Result. Free transverse vibrations of multi–span beams of constant cross-section (within each j-th span Aj, and Gj) are investigated taking into account elastic-damping discrete supports. Free and forced harmonic vibrations of the beam from vector kinematic and force perturbations are considered. Examples of solutions for various conditions of fixing a three-span beam at different point masses are given.Conclusion. The author’s development can be adapted to the fluctuations of the continuo-discrete rods. This algorithm allows you to determine the natural frequencies and forms of free oscillations. It is also possible to calculate multi-span rods for the simultaneous action of vector kinematic and dynamic loads.
The prototype of the system for the formation of an individual learning path
Authors: Aslanov T. G. , Abidova M. Sh. , Maksudov M. M. , Tagirov H. Yu. , Magomedov M. M.
Published: August 2023

Objective. The purpose of the study is to identify the dependence of the quality of education in a general educational organization on the educational environment.Method. To determine the influence of various factors on the quality of education, an artificial neural network was trained, for which statistical data were previously collected on the participants in the educational process in the ANEO “Knowledge House”.Result. An artificial neural network has been implemented, which makes it possible to identify the dependence of individual elements of the educational environment on the quality of education in a general educational organization. The training of the artificial neural network showed an insignificant error in the assessment on a ten-point scale, which, when converted to a five-point system, was about 0.5 points.Conclusion. The proposed method makes it possible to qualitatively and quantitatively assess the progress of students using an artificial neural network according to data that correlates with the progress of a student in an educational organization.
Development of a computer simulation model of a three-phase asynchronous electric drive using an adjustable transistor reducer
Authors: Eremochkin S. Yu. , Zhukov A. A. , Dorokhov D. V.
Published: August 2023

Objective. The purpose of this work is to study the characteristics of an electric drive using a transistor reducer of an induction motor using computer simulation tools.Method. The study is based on simulation methods.Result. The values of the angular velocity are determined at fixed values of the moment of resistance for constructing a static mechanical characteristic, as well as the values of the efficiency and power factor with increasing active power on the motor shaft. The values of similar quantities for the electric motor, which is powered by a phase-shifting capacitor, are determined. The dependences of the power factor and efficiency on the active power on the motor shaft are determined.Conclusion. The data obtained as a result of computer simulation testify to the effectiveness of the proposed transistor reducer.
Application of modified genetic algorithms for solving evolutionary problems of the theory of schedules
Authors: Zakharov D. S.
Published: August 2023

Objective. The article proposes ways to modify genetic algorithms used to automate the process of scheduling.Method. The methods of evolutionary calculations, the theory of schedules, genetic algorithms, the developed software product are used in the work.Result. It is established that the construction of the initial GA population for solving the problem is an extremely important criterion for the convergence of the result. It has been established that the two-stage mutation also allows individuals to be adjusted in the right direction, thereby reducing the time required to perform GA work.Conclusion. Studies show that the developed methods of GA modification can greatly affect the performance of software in the automated scheduling of educational institutions, a scheme of GA operation has been developed, methods of GA modification have been presented and tested.
Telehealth Use During the COVID-19 Pandemic Among Veterans and Nonveterans: Web-Based Survey Study
Authors: Shoemaker Holly E , Thorpe Alistair , Stevens Vanessa , Butler Jorie M , Drews Frank A , Burpo Nicole , Scherer Laura D , Fagerlin Angela
Published: August 2023

Background

In the first year of the COVID-19 pandemic, studies reported delays in health care usage due to safety concerns. Delays in care may result in increased morbidity and mortality from otherwise treatable conditions. Telehealth provides a safe alternative for patients to receive care when other circumstances make in-person care unavailable or unsafe, but information on patient experiences is limited. Understanding which people are more or less likely to use telehealth and their experiences can help tailor outreach efforts to maximize the impact of telehealth.

Objective

This study aims to examine the characteristics of telehealth users and nonusers and their reported experiences among veteran and nonveteran respondents.

Methods

A nationwide web-based survey of current behaviors and health care experiences was conducted in December 2020-March 2021. The survey consisted of 3 waves, and the first wave is assessed here. Respondents included US adults participating in Qualtrics web-based panels. Primary outcomes were self-reported telehealth use and number of telehealth visits. The analysis used a 2-part regression model examining the association between telehealth use and the number of visits with respondent characteristics.

Results

There were 2085 participants in the first wave, and 898 (43.1%) reported using telehealth since the pandemic began. Most veterans who used telehealth reported much or somewhat preferring an in-person visit (336/474, 70.9%), while slightly less than half of nonveterans (189/424, 44.6%) reported this preference. While there was no significant difference between veteran and nonveteran likelihood of using telehealth (odds ratio [OR] 1.33, 95% CI 0.97-1.82), veterans were likely to have more visits when they did use it (incidence rate ratio [IRR] 1.49, 95% CI 1.07-2.07). Individuals were less likely to use telehealth and reported fewer visits if they were 55 years and older (OR 0.39, 95% CI 0.25-0.62 for ages 55-64 years; IRR 0.43, 95% CI 0.28-0.66) or lived in a small city (OR 0.63, 95% CI 0.43-0.92; IRR 0.71, 95% CI 0.51-0.99). Receiving health care partly or primarily at the Veterans Health Administration (VA) was associated with telehealth use (primarily VA: OR 3.25, 95% CI 2.20-4.81; equal mix: OR 2.18, 95% CI 1.40-3.39) and more telehealth visits (primarily VA: IRR 1.5, 95% CI 1.10-2.04; equal mix: IRR 1.57, 95% CI 1.11-2.24).

Conclusions

Telehealth will likely continue to be an important source of health care for patients, especially following situations like the COVID-19 pandemic. Some groups who may benefit from telehealth are still underserved. Telehealth services and outreach should be improved to provide accessible care for all.
Attributes, Quality, and Downloads of Dementia-Related Mobile Apps for Patients With Dementia and Their Caregivers: App Review and Evaluation Study (Preprint)
Authors: Chen Tzu Han , Lee Shin-Da , Ma Wei-Fen
Published: August 2023

BACKGROUND

The adoption of mobile health (mHealth) apps among older adults (>65 years) is rapidly increasing. However, use of such apps has not been fully effective in supporting people with dementia and their caregivers in their daily lives. This is mainly attributed to the heterogeneous quality of mHealth apps, highlighting the need for improved app quality in the development of dementia-related mHealth apps.

OBJECTIVE

The aims of this study were (1) to assess the quality and content of mobile apps for dementia management and (2) to investigate the relationship between app quality and download numbers.

METHODS

We reviewed dementia-related mHealth apps available in the Google Play Store and Apple App Store in Taiwan. The identified mobile apps were stratified according to a random sampling approach and evaluated by five independent reviewers with sufficient training and proficiency in the field of mHealth and the related health care sector. App quality was scored according to the user version of the Mobile Application Rating Scale. A correlation analysis was then performed between the app quality score and number of app downloads.

RESULTS

Among the 17 apps that were evaluated, only one was specifically designed to provide dementia-related education. The mean score for the overall app quality was 3.35 (SD 0.56), with the engagement (mean 3.04, SD 0.82) and information (mean 3.14, SD 0.88) sections of the scale receiving the lowest ratings. Our analyses showed clear differences between the top three– and bottom three–rated apps, particularly in the entertainment and interest subsections of the engagement category where the ratings ranged from 1.4 to 5. The top three apps had a common feature in their interface, which included memory, attention, focus, calculation, and speed-training games, whereas the apps that received lower ratings were found to be deficient in providing adequate information. Although there was a correlation between the number of downloads (5000 or more) and app quality (t15=4.087, P<.001), this may not be a significant determinant of the app’s perceived impact.

CONCLUSIONS

The quality of dementia-related mHealth apps is highly variable. In particular, our results show that the top three quality apps performed well in terms of engagement and information, and they all received more than 5000 downloads. The findings of this study are limited due to the small sample size and possibility of disregarding exceptional occurrences. Publicly available expert ratings of mobile apps could help people with dementia and their caregivers choose a quality mHealth app.
Investigating the Approach of Using Behavior Change Techniques in the Field of Mobile ‎Applications: A Systematic Review‎ (Preprint)
Authors: Kheirdoust Azam , Mazaheri Habibi Mohammad Reza , Emadzadeh Ali , Jafarzadeh Esfehani Ali , Agha Seyyed Esmaeil Amiri Fariba Sadat , Ghaddaripour Kosar , Eslami Saeid
Published: August 2023

BACKGROUND

By using behavior change techniques (BCTs) and by creating awareness and motivation in patients, it is possible to ‎help improve people's health. In recent years, mobile technologies are increasingly used in health care, facilitating ‎adherence ‎to‎ chronic disease management, changing behavior‏,‏‎ and improving people's lifestyles.‎

OBJECTIVE

This systematic review aims to assess more effective behavior change techniques in increasing adherence in the ‎management of chronic diseases, promoting behavior change‏,‏‎ and improving people's lifestyles in the field of ‎mobile applications.‎

METHODS

A systematic review of English-language studies was conducted by searching in the reliable scientific databases ‎PubMed, Scopus, Web of Science, and the Cochrane Library on February 12, 2023. A total of 8042 articles were ‎obtained, 16 of which were relevant to the objectives of the present study.‎

RESULTS

‎10 cases (62.5%) out of 16 reviewed studies investigated App Store or Google Play Android ‎applications, some of which used the MARS tool to evaluate applications.‎‏ ‏Studies on maintenance ‎treatments and lifestyle modification, including diet and physical activity, had a greater share ‎‎(67%). In accordance with the main purpose of this study, all studies pointed to the positive effect ‎of behavior change techniques (100%). Regarding the number of behavior change techniques, at ‎least one technique and a maximum of 53 techniques were mentioned, but none of them mentioned ‎the reason for choosing the desired behavior change technique. In this study, based on the behavior ‎change wheel and its mapping to the BCT taxonomy in the Michie protocol, and citing scientific ‎reasons, two techniques are selected and proposed as the default techniques in the field of mobile ‎applications.‎

CONCLUSIONS

The results of this systematic review show that the use of behavior change techniques in health ‎interventions, especially mobile phone applications plays an effective role in achieving the health ‎of patients. However, little research has been done in this field, and it is necessary to pay more ‎attention to the use of these techniques in mobile applications in future studies.‎
Effect of Different Stabilizers on Spherical Agglomerates of Montelukast Sodium by Quasi Emulsion Solvent Diffusion (QESD)
Authors: J Hasiful Arabi , L Subramanian , M Rajesh , MS Arun Kumar
Published: August 2023

Abstract: The present study was focused on the spherical crystallization of an asthmatic drug, Montelukast Sodium (MLS) using quasi emulsion solvent diffusion (QESD) technique in which distilled water was an external phase and the internal phase consisted of Ethanol which acts as good solvent and Ethyl acetate as a bridging liquid for recrystallization and agglomeration process. Apart from being poorly water soluble, MLS exhibits poor flow and compressibility. The spherical agglomeration was carried out in the presence of different stabilizers like acacia, PEG 4000, sodium lauryl sulphate, span 40 and tween 80. The prepared agglomerates were characterized in terms of production yield, drug content, solubility, in-vitro release profile, Xray diffraction (XRD), and Fourier transform infra red spectroscopy (FT-IR).The optimized spherical agglomerates exhibited excellent physicochemical and micromeritic properties, solubility and dissolution rate when compared with pure drug .The XRD also revealed a characteristic decrease in crystallinity. The dissolution studies demonstrated a marked increase in the dissolution rate. FTIR study reveals there are no chemical changes in prepared recrystallized agglomerates. The considerable improvement in the dissolution rate of MLS from optimized crystal formulation was attributed to the wetting effect of polymers, decreased drug crystallinity, altered surface morphology and micronization. If this process can be scaled-up to manufacturing level, this technology has the potential to provide the directly compressed spherical agglomerates with improving the physicochemical and micromeritic properties
20-Mode Universal Quantum Photonic Processor
Authors: Taballione Caterina , Anguita Malaquias Correa , de Goede Michiel , Venderbosch Pim , Kassenberg Ben , Snijders Henk , Kannan Narasimhan , Vleeshouwers Ward L. , Smith Devin , Epping Jörn P. , van der Meer Reinier , Pinkse Pepijn W. H. , van den Vlekkert Hans , Renema Jelmer J.
Published: August 2023

Integrated photonics is an essential technology for optical quantum computing. Universal, phase-stable, reconfigurable multimode interferometers (quantum photonic processors) enable manipulation of photonic quantum states and are one of the main components of photonic quantum computers in various architectures. In this paper, we report the realization of the largest quantum photonic processor to date. The processor enables arbitrary unitary transformations on its 20 input modes with an amplitude fidelity of FHaar=97.4% and FPerm=99.5% for Haar-random and permutation matrices, respectively, an optical loss of 2.9 dB averaged over all modes, and high-visibility quantum interference with VHOM=98%. The processor is realized in Si3N4 waveguides and is actively cooled by a Peltier element.
“Debaixo de sua real proteção a nossa causa ”: poderes regionais e questões de autonomia na Independência (1820-1823)
Authors: Antônio Edna Maria Matos
Published: August 2023

O artigo discute questões de poder regional no contexto das lutas pela independência a partir do exame do processo ocorrido entre as capitanias de Sergipe e Bahia. Pretende-se realçar a dimensão das disputas internas e elaboração de projetos políticos específicos envolvendo vários níveis de autonomias, que revelam conflitos em torno de subalternidade de territórios e articulação entre sociedades e espaços coloniais. Para essa problematização, contextualiza-se o reconhecimento dos poderes regionais, também em sua dimensão interna, para a discussão da Independência e, na sequência, apresenta-se o problema pela perspectiva de planejamento administrativo do período joanino para fins de fortalecimento de poder monárquico. Consultaram-se bibliografia e documentos históricos que expressam as razões, as questões e os dilemas postos às elites regionais entrelaçadas no amplo, profundo e criativo processo de crise do colonialismo português na América de que resultou nossa Independência.
Review of the conference book New outlooks for the scholarly research in corporate governance
Authors: Kostyuk Alexander
Published: August 2023

This review covers the conference book titled “New outlooks for the scholarly research in corporate governance”, edited by Marco Tutino, Valentina Santolamazza, and Alexander Kostyuk (Virtus Interpress, 2023; ISBN: 978-617-7309-23-8). Modern corporate governance is indeed a dynamic and changing set of guidelines, practices, and procedures that are used to steer and manage a company forward. International conference New Outlooks for Scholarly Research in Corporate Governance held online on June 8, 2023, approached in investigating factors that are inherent in today’s discussions of corporate governance deviate
Regulation and challenges of youth employment in the developing country
Authors: Ismajli Naim , Ismajli Meriton , Gashi Adelina
Published: August 2023

The problem of youth unemployment has started to receive attention in a relevant way recently, especially in Europe, where the percentage of unemployment registered for this category of the population is relatively greater than that for the adult population (Perugini & Signorelli, 2010), also being influenced by the last financial crisis (Choudhry et al., 2012). Youth unemployment is a critical social issue because it is linked to a number of aspects of society (Yamamoto, 2011). The purpose of the treatment of this paper is to identify the barriers faced by the young people of Kosovo to enter the labor market. The study uses the quantitative research method, through the use of an online questionnaire, a survey was participated by 496 respondents. The econometric model used in this study is the structural equation model (SEM). The empirical results from the SEM model show that the most important factor is the lack of work experience, which is a barrier to the employment of young people in Kosovo. The results of this paper are important to understand the importance of effectiveness in the design of policies for the elimination of barriers to the employment of young people in Kosovo.
Judicial governance and its role in achieving justice effectiveness
Authors: Kandeel Moustafa Elmetwaly , Alqatawneh Ibrahim Suleiman , Moussa Ahmad Fekry , Jaffal Zeyad Mohammad
Published: August 2023

Using the analytical method, the purpose of this paper is to emphasize some constitutional and legal principles, whose application and implementation will lead to UAE judiciary governance. Six major principles can be summarized as a result of these principles (Khalil, 2022). A few of these principles serve as a foundation for the UAE judicial governance; others serve as a guarantee for judicial governance. Further, the principles of openness of the judiciary, a confrontation between litigants, and appeals against court rulings ensure judicial governance (Alsubaie, 2022). At the end of this paper, a number of results shall be confirmed. The UAE judiciary will definitely preserve the right to litigation as a result of its governance. Additionally, all citizens and residents shall have the right to initiate legal proceedings without discrimination, provided that the following rights are satisfied: the right to legal counsel, the right to confrontation between litigants, and the right to appeal against court rulings.
The new income statement of insurance companies in IFRS 17: First application issues
Authors: Pucci Sabrina , Lupatelli Umberto , Vaccarezza Jacopo
Published: August 2023

The introduction of International Financial Reporting Standards (IFRS) 17 represents for the insurance sector a deep change both in the presentation of the annual statements and in the main ratios that will be analyse to understand the key factors of the insurance business. Some of the major changes regard the economic items and the income statement. This study, that is only a first step analysis, will do a comparison of the different accounting principles framework with the scope to verify and evaluate the main impacts of the new contest on transparency and disclosure for the stakeholders.
Does it make a difference when internalized? Exploring different CSR approaches predicting firm competitiveness
Authors: Sun Tingting
Published: August 2023

Drawing upon signaling and organizational commitment theories, this study clusters unobtrusive corporate social responsibility (CSR) behaviors from the commitment and compliance dimensions to different CSR approaches, and examine how these approaches predict firm competitiveness using secondary data from Chinese public companies. It contributes to the CSR literature by providing empirical evidence that internalized CSR contributes to increasing firm competitiveness. It also contributes to the literature on firm competitiveness by identifying three aspects of core competence — financial, technological and dynamic capabilities — and their corresponding correlations with firm competitiveness, thus integrating both the resource-based view (RBV) and the dynamic capability perspective. The negative correlation discovered between dynamic capability and firm competitiveness challenges the views of the literature and indicates the existence of additional facets and potential boundaries of dynamic capability in the context of strongly collective cultures, such as China.