bluuebunny/crossref_metadata_2025 huggingface dataset:
Acute-on-Chronic Liver Failure: Diagnóstico al Transplante Hepático
Authors: Cronst Jane , Pinto Marcelo de Abreu , Prediger Lucas , Silva Rafaela Kathrine , Arruda Soraia , Chedid Marcio Fernandes
Published: October 2022

Resumen:Introducción: Pacientes en acute on chronic liver failure (ACLF)presentan características distintas de aquellas presentadas por pacientes hepatopatas no ACLF. El grado de ACLF impacta en el desenlace con o sin el transplante, habiendo divergencias en la literatura principalmente en lo que se refiere al pronóstico postransplante. Objetivos: Revisar los diferentes aspectos de los pacientes en ACLF, abarcando los conceptos del síndrome adoptados por diversas instituciones, el tratamiento de las complicaciones, y describir el conocimiento acerca de los desenlaces con o sin transplante de los portadores del síndrome reportados en la literatura. Métodos: Fueron incluidos 22 artículos encontrados en la búsqueda de bases de datos PubMed, Medline y Biblioteca Electrónica Científica Online (SciELO) con los descriptores “ACLF definitions” y “Liver transplantation ACLF”. Los conceptos y datos apuntados en los textos seleccionados fueron comparados y utilizados como base para redactar este artículo. Resultados: Existen algunas diferencias en la definición del síndrome, variando especialmente entre los países del Occidente y los del Oriente. Pacientes esperando transplante hepático en ACLFpresentan características distintas de aquellas presentadas por pacientes no ACLF. El grado de ACLF también impacta en el desenlace con o sin el transplante, habiendo divergencias en la literatura principalmente en lo que se refiere al pronóstico postransplante de los pacientes en ACLF 3, con tendencia cada vez mayor en la indicación del transplante incluso para estos pacientes. Conclusiones: Los desenlaces varían entre pacientes en ACLF de acuerdo con el grado de la enfermedad. El transplante hepático ha sido más frecuentemente indicado en ACLF 3, habiendo el tiempo de espera impactado los resultados. Son necesarios más estudios para definir cuáles subgrupos de pacientes se benefician más del transplante hepático.
Acute-on-Chronic Liver Failure: Diagnóstico ao Transplante Hepático
Authors: Cronst Jane , Pinto Marcelo de Abreu , Prediger Lucas , Silva Rafaela Kathrine , Arruda Soraia , Chedid Marcio Fernandes
Published: October 2022

Introdução: Pacientes em acute on chronic liver failure (ACLF) apresentam características distintas daquelas apresentadas por pacientes hepatopatas não ACLF. O grau de ACLF impacta no desfecho com ou sem o transplante, havendo divergências na literatura principalmente no que tange ao prognóstico pós-transplante. Objetivos: Revisar os diferentes aspectos dos pacientes em ACLF, abrangendo os conceitos da síndrome adotados por diversas instituições, o tratamento das complicações, e descrever o conhecimento acerca dos desfechos com ou sem transplante dos portadores da síndrome reportados na literatura. Métodos: Foram incluídos 22 artigos encontrados na busca de bases de dados PubMed, Medline e Biblioteca Eletrônica Científica Online (SciELO) com os descritores “ACLF definitions” e “Liver transplantation ACLF”. Os conceitos e dados apontados nos textos selecionados foram comparados e utilizados como base para redigir este artigo. Resultados: Existem algumas diferenças na definição da síndrome, variando especialmente entre os países do Ocidente e os do Oriente. Pacientes aguardando transplante hepático em ACLF apresentam características distintas daquelas apresentadas por pacientes não ACLF. O grau de ACLF também impacta no desfecho com ou sem o transplante, havendo divergências na literatura principalmente no que tange ao prognóstico pós-transplante dos pacientes em ACLF 3, com tendência cada vez maior na indicação do transplante mesmo para esses pacientes. Conclusões: Os desfechos variam entre pacientes em ACLF de acordo com o grau da doença. O transplante hepático tem sido mais frequentemente indicado em ACLF 3, tendo o tempo de espera impactado os resultados. São necessários mais estudos para definir quais subgrupos de pacientes se beneficiam mais do transplante hepático.
SIMULASI UJI PAPARAN SINAR-X MOBILE PADA PEMERIKSAAN RONTGEN DADA DI RSUP FATMAWATI
Authors:   Rumah Sakit Umum Pusat Fatmawati, Jakarta, Indonesia, Mubarok Sayid , Hervin Dwy
Published: October 2022

SIMULATION OF MOBILE X-RAY EXPOSURE TEST ON CHEST X-RAY EXAMINATION AT FATMAWATI HOSPITAL. Chest X-ray examinations using mobile X-rays are increasing, especially due to the Covid-19 pandemic as an early detection as well as for patient monitoring needs. Radiation safety aspects in chest X-ray examinations using mobile X-rays need to be studied considering that they are generally used in patient inpatient rooms. This study aims to simulate the amount of scattered radiation from a chest X-ray examination using a mobile X-ray to assess the level of radiation safety and the required radiation protection equipment. First, the primary radiation dose was measured to assess the estimated dose received by the patient, then the scattering radiation was measured (maximum dose rate and accumulated dose) using 20 cm PMMA phantom scattering media in various directions at a distance of 1, 2, 3 and 4 m. and with variations without radiation shielding, with 0.5 mm Pb apron radiation protection and with 2 mm Pb mobile shielding. The result of the primary radiation dose is 0.145 ± 0.003 mGy, which is still below the DRL value. While the dose rate analysis results show that up to a distance of 4 m the dose rate value still exceeds the radiation safe limit, a radiation protection is needed in the form of a 0.5 mm Pb apron with a distance of more than 2 m in order to obtain a safe dose rate for the general public. The results of the analysis of the accumulation of scattered doses, the safe distance without using radiation shields is more than equal to 2 m. It is recommended that the patient and staff distance from the mobile X-ray radiation source is at least 2 m and use a radiation protection such as Pb apron or mobile shielding. Keywords: Radiation exposure, Radiation scatter, Dose Rate
PEMANFAATAN TIMBAL BEKAS PADA ALAT POTEKSI RADIASI APR SEBAGAI UPAYA PENERAPAN PROTEKSI RADIASI
Authors:   Rumah Sakit Pelni Jakarta, Kota Jakarta Barat, Indonesia, Ardiyanti Desmalia Putri , Simarmata Tigor Ignasius ,   Rumah Sakit Premier Jatinegara, Jakarta, Indonesia, Saragih Jhon Hadearon ,   Mayapada Hospital Tangerang, Indonesia
Published: October 2022

Radiation protection is an action taken to reduce the damaging effects of radiation caused by radiation exposure. Many APRs are damaged or unfit for use where APR is used every day and for a long duration of inspection, due to various factors, including storage methods and incorrect procedures for using APR. The purpose of this research is to utilize Pb which is not suitable for use for repairs as a step to limit and optimize radiation protection for radiation workers and patients and to ensure its suitability from damage. This type of research is qualitative by using the Lead Laminated technique. The study used samples, namely Thyroid Shield with a thickness of 0.5 mm Pb and other supporting tools in the form of AIbon glue as an adhesive as well as handscoons, N95 masks, and aprons as personal protective equipment. Methods of collecting data were observation, documentation, and testing of the thyroid shield. The thyroid shield test was carried out using the MSCT Optima 660 64 slices and DR Y-Sio Max modalities. The data collection process was carried out in 3 stages, namely pre-repair, after post-repair, and after observation within 2 months. Based on the observations in Table 2, it was obtained that the previous cracks were well covered and there were no cracks either in the old location or in the new location. The results of the observations showed promising results in repairing the radiation protection device (APR) on the thyroid shield sample using the lead laminated technique. The image results show that there is no crack after repairing the thyroid shield. However, there are pieces of Pb from the repair that are loose from the thyroid shield, which could be due to uneven gluing and less drying during the repair process. Keywords: repair, radiation protection device, thyroid shield
UJI KUALITAS APRON UNTUK OPTIMISASI PROTEKSI RADIASI BAGI PASIEN DI RUANGAN RADIOLOGI DIAGNOSTIK DAN INTERVENSIONAL
Authors:   Rumah Sakit Sentra Medika, Bogor, Indonesia, Alzufri Habib Syeh , Nurmiati Dede
Published: October 2022

APRON QUALITY TEST FOR OPTIMIZATION OF RADIATION PROTECTION FOR PATIENTS IN RADIOLOGY OF DIAGNOSTIC AND INTERVENTIONAL. Apron is a body protective device that can reduce the dose of scattered radiation exposure from x-ray beams, but in the use of an apron it is often neglected because of impracticality and improper laying procedures that cause damage to the lead rubber plate (Pb) inside so that the function of apron in protecting radiation is not optimal and most likely to get high dose from scattered radiation. This test aims to ensure that radiation protection equipment can provide optimal protection. The apron quality test methods analyzed were visual, tactile and fluoroscopy. In addition, the analysis of the quality of the apron is evaluated by looking at the level of damage and reviewing the graph of the relationship between area of defect and equivalent dose. The results of the radiation dose measurement based on the irradiation process on the apron in the radiology room there was 1 damaged apron of 3 aprons, while in the ESWL room there were 1 apron and in the cathlab room there were 4 aprons still in good condition. Based on the level of damage to the apron in the radiology room, there were several types of damage, namely absent lead type = 1.75 mSv, Crack type = 0.67 mSv and stiching type = 0.47 mSv. The results of the graph between the dose equivalent to the area of defect obtained a linear relationship, meaning that the more extensive the damage to an apron, the greater the radiation dose received by the patient and the patient's companion. Therefore, for the apron that is not feasible, based on the dose and area, it is better to replace the apron so that providing optimal protection and prevent unnecessary exposure. Keywords: Optimization, Radiation protection, Equivalent dose, Defect
KUALITAS CITRA SIDIK TULANG DENGAN PEMBERIAN DOSIS RADIOFARMAKA 99mTc-MDP BERDASARKAN BERAT BADAN DI INSTALASI KEDOKTERAN NUKLIR RS HASAN SADIKIN BANDUNG
Authors:   Instalasi Kedokteran Nuklir dan Pencitraan Molekular RSUP dr Hasan Sadikin Bandung, Indonesia, Shintawati Rini , Kartamihadja A. Hussein S.
Published: October 2022

A bone scan procedure using radiopharmaceutical 99mTc-MDP (Methylenediphosphonate) is an examination to help establish diagnostics in detecting metastases (spread) of cancer cells to bone. The dose given in this examination was according to the instructions from the Europe Association of Nuclear Medicine (EANM), the average dose given was 500MBq and also based on the guidelines in the attachment to the Regulation of the Head of Bapeten No. 17 of 2012 was 700 MBq. Justification for giving this dose will undoubtedly affect the acceptance of the exposure dose by the patient himself. On the other hand, giving a minimal dose sometimes creates doubts and concerns about the final result or poor image quality. Fulfillment of this image quality can be seen or calculated using ratio assessment. The results of this ratio assessment will show good image quality if it meets the target to background ratio results, which is the accumulation in the primary and background objects > from 5:1. The result of the intensity ratio is obtained from the ROI (Region of Interest) in the lumbar spine divided by ROI (Region of Interest) in the non-bone (abdominal area), which is considered the background. Giving a low dose is expected so that the exposure dose is small, but the picture results are still fulfilled. Carried out the research by providing a dose of Bone scan examination based on the patient's body weight of 10 MBq/kg, then calculating the Target Background to Ratio on the results of scans in the lumbar region 1-5. Development of the research obtained the number of patients as many as 51 patients with three people removed from the study so that the number of patients who took data was 48 patients consisting of 38 women and ten men. The results of the calculation included 33 patients who met the ratio results (>5), while 15 patients still did not meet the image quality criteria (<5). The Conclusion of the ratio that meets the value >5 is 69%, and those who do not meet the requirements are 31%. Keywords: Bone Scan, Ratio Results, 99mTc MDP
ESTIMASI DAN AUDIT DOSIS RADIASI PASIEN PADA PEMERIKSAAN RADIOGRAFI KONVENSIONAL TORAKS PA DENGAN TEKNIK HIGH KVP
Authors:   Departement Radiology, MRCCC Siloam Hospitals Semanggi, Jakarta, Indonesia, Raharja Hanendya Disha Randy , Supit Nina ISH , Haposan Ucok Noptua
Published: October 2022

Research about estimation and dose audit of patients' radiation on examination about thorax PA conventional radiography with high kV technique has been conducted in MRCCC Siloam Hospitals Semanggi. The research has been done on 305 patients aged around 15 years old who got thorax examinations. They consist of 129 male patients and 176 female patients. The characteristics of patients' age are between 18-86 years old, and their average age is 44.2 years old. Their weight range is between 38-120 kg, and their average weight is 66.8 kg. The thorax PA conventional radiography examination uses kVp 125, and the content of mAs is 0.5-1.4 mAs, with an average of 0.8 mAs. The dosage of patients with INAK and ESAK are counted from the outcome similarity graph of the radiation from the X-ray craft. Data analysis shows a linear increase of INAK and ESAK with a linear correlation consecutive of 0.9969 and 1 toward the rise in mAs. The higher the mAs, the higher the patient's dose of radiation also becomes bigger because mAs represent the quantity of radiation so that the amount of photons produced by the X-ray tube becomes bigger. The research result shows that the average increase of INAK and ESAK consecutive is 0.11 mGy and 0.15 mGy, with a typical value of INAK at 0.1 mGy and ESAK at 0.14 mGy. The average ESAK on the research is compared with some reference data, and the result of ESAK in MRCCC Siloam Hospitals Semanggi is under some reference data. The dose audit is the establishment of typical value, and it is compared with national DRL based on the regulation of the head of BAPETEN about stipulation of Indonesia Diagnostic Reference Level Value no. 1211/K/V/2021 on thorax PA examination. The examination of thorax PA about INAK and ESAK national DRL consecutive is 0.3 mGy and 0.4 mGy. Therefore, the result of the dose audit about establishing typical value on the study about thorax PA conventional radiography in MRCCCC Siloam Hospitals Semanggi is under national DRL. The follow-up of the dose audit is to keep the examination protocol and evaluate typical values periodically. The high kVp technique on the conventional radiography examination can reduce the patient's radiation dose. Keywords: Radiation Dose, Conventional Radiography, Thorax PA. High kVp Technique, Diagnostic Reference Levels
PEMANTAUAN DOSIS LENSA MATA HP(3) STAF CATHLAB MENGGUNAKAN SOCA DOSIMETER
Authors:   Jurusan Fisika FMIPA Universitas Brawijaya, Malang, Indonesia, Desinta Rosa , Latifah Risalatul ,   Jurusan Fisika FMIPA Universitas Brawijaya, Malang, Indonesia, Santoso Rio Imam ,   Fisikawan Medik, RS Pusat Jantung dan Pembuluh Darah Terpadu Nasional Harapan Kita, Jakarta, Indonesia, Bunawas Bunawas ,   NuklindoLab – Koperasi JKRL, Tangerang Selatan, Indonesia
Published: October 2022

MONITORING OF EYE LENS DOSE HP(3) CATHLAB STAFF USING SOCA DOSIMETER. The International Commission on Radiological Protection (ICRP) reduced the cataract threshold dose from 2‒5 Gy to 0.5 Gy, followed by a decrease in the dose limit value (NBD) of the radiation worker's eye lens to 20 mSv/year. Cathlab staff is one of the workers vulnerable to receiving high doses of eye lenses because they work near radiation sources, so staff's eye lens doses need to be monitored. Monitoring is carried out to analyze the dose of eye lenses received by workers and ensure workers are well protected. Eye lens measurement is carried out at Hp(3) or a depth of 3 mm because the lens is sensitive to radiation. Monitoring was carried out for one week on 14 staff (doctors, nurses, and radiographers) and four procedures with an eyepiece dosimeter (SOCA Dosimeter). The eye lens dose obtained for a week ranged from 0.108 – 1.642 mSv, and monitoring per procedure was 0.033 – 0.393 mSv. The annual dose received by workers is based on estimates mostly exceeding the NBD, so tracking with an eye lens dosimeter needs to be done, and eye protection equipment needs to be used to reduce the eye lens dose received. Keywords: Cathlab staff, eye lens dose Hp(3), SOCA dosimeter
Plantas útiles de la familia Amaranthaceae en el estado de Aguascalientes, México
Authors: Sandoval Ortega Manuel Higinio , Siqueiros Delgado Maria Elena
Published: October 2022

La familia Amaranthaceae tiene una distribución geográfica cosmopolita, sus especies habitan ambientes áridos, hábitats salinos y áreas perturbadas. Debido al considerable número de especies de esta familia localizadas en el estado de Aguascalientes, es posible que algunas de ellas tengan un uso y sean comercializadas. Con el objetivo de determinar cuántas especies de la familia Amaranthaceae son utilizadas en Aguascalientes y cuáles se comercializan, se visitaron mercados y se realizaron entrevistas a 26 informantes de 13 poblados del estado, la información obtenida fue complementada con datos obtenidos de bibliografía especializada para conocer usos potenciales. Solo 11 de las 29 especies reportadas en Aguascalientes son utilizadas, principalmente como comestibles y medicinales, y únicamente siete son comercializadas. Se identificaron también cuatro especies con algún uso potencial, dando un total de 15 que pueden ser utilizadas y que representan más del 50 % de las especies de la familia Amaranthaceae presentes en el estado.

DOI: https://doi.org/10.54167/tch.v13i1.324
FLOATING TOURISM DESIGN WITH ECOTURISM ARCHITECTURAL APPROACH PERANCANGAN WISATA APUNG DENGAN PENDEKATAN ARSITEKTUR EKOTURISME
Authors: Vikriyanto Agus , Mandaka Mutiawati , Susanti Anityas Dian
Published: October 2022

Indonesia merupakan salah satu negara yang mengarah ke perkembangan industri yang menghasilkan pertumbuhan perekonomian yang cepat dalam menyediakan lapangan pekerjaan, standar peningkatan penghasilan standar hidup serta menstimulasi sektor-sektor produktivitas lainya. Selain itu negara Indonesia juga memiliki potensi dalam perkembangan pada sektor pariwisata. Banyak potensi dalam pariwisata, salah satunya keragaman keindahan alam, budaya setempat maupun agama yang dapat di jadikan modal untuk meningkatkan kesejahteraan dan kemakmuran rakyat Indonesia. Kekayaan alam dan budaya yang ada di Indonesia juga harus di lestarikan agar kebudayaan atau alam di Indonesia di kenal oleh manca negara, salah satunya ialah wisata kampong apung. Perkembangan wisata apung di Indonesia sangat kurang, padahal wisata ini dapat di manfaatkan untuk perekonomian dan sekaligus dapat memasukan potensi budaya setempat serta melestarikan alam dan budaya agar tidak hilang. Adapun tujuan perancangan ini nantinya akan menjadi pusat wisata apung di Jawa Tengah untuk membantu perekonomian masyarakat setempat. Pendekatan arsitektur ecotourism diangkat sebagai respon terhadap tapak di sekitar waduk Rowo Jombor.
Rekonstruksi Kristologi Logos Menjawab Tantangan Dekonstruksi Terma Logosentrisme dalam Tinjauan Biblika
Authors: Belay Yosep
Published: October 2022

The concept of logos in the Christian faith does not only refer to theological ideas but also touches on the issue of the Christian worldview which as a whole refers to Christ as its centrality. The concept is suspected of being a form of logocentrism (grand narrative) that forms polarization and negation of the external world. Through deconstruction readings, contemporary cultural critics criticize Christian logocentrism. The purpose of reading deconstruction is to change the general understanding, both in philosophy, science, and Christian theology strategies regarding logos with two critical approaches. First, criticizing semantics in terms of logos and second, criticizing the politics of the text through which ideology is constructed and has implications for socio-cultural subordination. This article analyzes and reconstructs logos theology and christology in an attempt to address the challenges of deconstruction. The method used by the writer is descriptive analysis and literature review. The results showed that the concept of Christian logos theology was different from Greek philosophy. In relation to the theory of deconstruction, the bivalence system which is the pattern of the semantic system of logos theology provides strict limits on the meaning system so that the assumptions of deconstruction criticism are irrelevant. Meanwhile, the logos christology approach in biblical studies provides answers to the issue of logocentrism in both theological, literary and Christian epistemological contexts.Â Abstrak Konsep logos dalam iman Kristen tidak hanya mengacu pada gagasan teologis namun juga menyinggung persoalan wawasan dunia Kristen yang secara keseluruan merujuk pada Kristus sebagai sentralitasnya. Konsep tersebut dicurigai sebagai bentuk logosentrisme (narasi besar) yang membentuk polarisasi dan negasi terhadap dunia eksternal. Melalui pembacaan dekonstruksi, kritikus budaya kontemporer mengkritisi logosentrisme Kristen. Tujuan pembacaan dekonstruksi untuk merombak pemahaman umum, baik dalam strategi filsafat, sains, maupun teologi Kristen mengenai logos dengan dua pendekatan kritis. Pertama, mengkritisi semantik pada terma logos dan kedua, mengkritisi politik teks yang melaluinya ideologi dikonstruksikan dan berimplikasi terhadap subordinasi sosial budaya. Artikel ini menganalisis dan merekonstruksi ulang teologi dan kristologi logos dalam usaha untuk menjawab tantangan dekonstruksi. Metode yang dugunakan penulis deskriptif analisis dan kajian literatur. Hasil penelitian menunjukkan konsep teologi logos Kristen berbeda dengan filsafat Yunani. Dalam kaitannya dengan teori dekonstruksi, sistem bivalensi yang menjadi pola sistem semantik teologi logos memberikan batasan tegas pada sistem makna sehingga asumsi kritik dekonstruksi tidak relevan. Sementara pendekatan kristologi logos dalam kajian biblika memberikan jawaban terhadap isu logosentrisme baik dalam konteks teologis, sastra maupun epistemologi Kristen.Â Kata Kunci: Kristologi. Logos, Logosentrisme, Dekonstruksi.
POLITIK HUKUM PIDANA TENTANG PENGATURAN TINDAK PIDANA DI INDONESIA DALAM KASUS NARKOTIKA
Authors: Koswara Andri
Published: October 2022

This study was conducted with the aim of being able to analyze legal politics in regulating illegal drugs and narcotics in Indonesia. This research will be carried out using a normative legal approach and will focus on an inventory of positive law, legal findings in cases in concreto, legal comparisons, legal principles and doctrines, legal history, and legal systematics. The data in this study came from various primary and secondary legal data. The primary legal data in this article comes from various laws and regulations that are still relevant to the subject of discussion, such as Law Number 35 of 2009 concerning Narcotics. The secondary legal data is in the form of various understandings of law in primary data. The results of this study found that narcotics legal politics is the core of the formation of a legal system that contains laws and regulations that will regulate various criminal acts. In Articles 111 and 112, there is a fairly severe prison sentence, in which imprisonment for a minimum of 4 years and a maximum of 20 years, up to the death penalty.
ANALISIS PENGARUH DANA ALOKASI UMUM DAN DANA ALOKASI KHUSUS TERHADAP TINGKAT PERTUMBUHAN EKONOMI DI KABUPATEN SIMEULUE
Authors: Murdaya Jojo , Syahril
Published: October 2022

This study seeks to analyze the effect of general allocation funds and special allocation funds on the level of economic growth in Semeulue Regency. In this study, quantitative research method was employed. Research sample was determined by using a saturated sample, namely to the entire population. The analysis used by the researcher is descriptive statistical analysis using multiple linear regression. From these results, it is concluded that the general allocation fund and the special allocation fund have a significant effect on economic growth. Multiple regression test resulted in constant -10,055, general allocation fund  1.715, and special allocation fund  4.079. The results of hypothesis testing show that general allocation funds has insignificant effect on economic growth in Simeulue Regency, and special funds have a significant effect of 90.10%, while the remaining 9,90% on economic growth influenced by other variables beyond this study.
Blefaritis: Etiologi, Klasifikasi, Diagnosis, dan Tata Laksana
Authors: Fernanda Marcella Dena
Published: October 2022

Blefaritis merupakan kondisi oftalmologis yang ditandai dengan inflamasi pada margo kelopak mata. Secara anatomis, blefaritis dibagi menjadi blefaritis anterior dan posterior. Pilihan terapi blefaritis telah mengalami perkembangan dalam beberapa tahun terakhir. Kompres hangat dan membersihkan kelopak mata masih menjadi regimen pengobatan dasar; penggunaan antibiotik, steroid, dan inhibitor calcineurin menunjukkan efikasi yang baik. Suplementasi dan berbagai prosedur intervensi mungkin dapat dipertimbangkan di masa depan.

Blepharitis is an ophthalmological condition characterized by inflammation of the eyelids. Anatomically, blepharitis is divided into anterior and posterior blepharitis. Therapeutic options for blepharitis have evolved in recent years. Warm compresses and eyelid hygiene are still the basic treatment regimen, but the use of antibiotics, steroids, and calcineurin inhibitors has shown good efficacy. Supplementations and various possible intervention procedures may be considered in the future.
Wanita 75 Tahun dengan Hipertensi Emergensi dan Unstable Angina Pectoris
Authors: Enggarela Asrina
Published: October 2022

Pendahuluan: Hipertensi emergensi adalah peningkatan tekanan darah secara substansial dan dihubungkan dengan adanya Hypertensive Mediated Organ Damage (HMOD) akut. Kondisi ini sering memerlukan intervensi menurunkan tekanan darah segera tetapi hati-hati, biasanya secara intravena. Kasus: Perempuan, 75 tahun, mengeluh tiba-tiba nyeri dada 4 jam sebelum masuk rumah sakit. Nyeri seperti ditindih dan menjalar hingga ke lengan kiri. Keluhan tidak berkurang dengan istirahat, disertai keringat dingin dan sesak napas. Tekanan darah 230/110 mmHg, nadi 122 kali/menit, pernapasan 26 kali/menit, saturasi oksigen 97%. Tidak ada gallop dan murmur pada auskultasi jantung. Pada EKG didapatkan irama sinus takikardia, prolonged QTc, ST depresi lead II, III, aVF, aVL, dan V4-V6. Foto toraks PA menemukan kardiomegali (ventrikel kiri), dan bonkopneumonia. Hasil laboratorium darah didapatkan leukositosis, tanpa peningkatan kadar enzim Troponin I dan CKMB. Pasien didiagnosis hipertensi emergensi dengan unstable angina pectoris. Simpulan: Hipertensi emergensi merupakan salah satu kasus kegawatdaruratan yang memerlukan diagnosis yang cepat dan tepat dan intervensi segera, biasanya dengan terapi intravena serta pengawasan di ICU.

Introduction: A hypertensive emergency is a substantially elevated blood pressure associated with acute Hypertensive Mediated Organ Damage (HMOD). This condition is often life-threatening, requiring immediate but careful intervention to lower blood pressure, usually with intravenous therapy. Case: A 75 year-old female presented with acute-onset chest pain started 4 hours before admission to the hospital. The chest pain was crushing in nature and radiating to the left arm accompanied by cold sweats and shortness of breath, not relieved with rest. Blood pressure was 230/110 mmHg, heart rate was 122 bpm and regular, oxygen saturation was 97%. No heart murmurs on cardiac auscultation. ECG showed tachycardia sinus rhythm, prolonged QTc, ST segment depression in lead II, III, aVF, aVL, and V4-V6. Chest X-ray showed cardiomegaly (left ventricle), and bronchopneumonia. Blood laboratory findings showed elevated white blood cells and normal level of Troponin I and CK-MB. The diagnosis was hypertensive emergency with unstable angina pectoris. Conclusion: Hypertensive emergency requires a fast and accurate diagnosis and immediate intervention, usually with intravenous therapy and ICU monitoring. The choice of drug and blood pressure target depends on the affected target organ and its clinical manifestations.

 
Penerapan Sistem Pengendalian Manajemen Terhadap Kinerja Karyawan pada Pt Nauli Sawit di Kelurahan Bajamas, Kecamatan Sirandorung
Authors: Sihotang Lidia , Putri Cindea Corycha , Amenda Jessy , Belisca Apra , Azhari Intan Putri
Published: October 2022

Latar Belakang : PT. Nauli Sawit adalah perusahaan swasta bergerak dalam bidang perkebunan dan mengelolahan buah kelapa sawit, berlokasi di Kelurahan Bajamas, Kecamatan Sirandorung, Kabupaten Tapanuli Tengah, Provinsi Sumatera Utara.

Tujuan : Penelitian ini bertujuan untuk, menganalisis apakah penerapan  sistem pengendalian manajemen yang diterapkan perusahaan sudah berjalan dengan baik dalam proses penerapan sistem pengendalian manajemen apakah ada kendala yang dialami oleh perusahaan beserta dengan solusi dari kendala?

Metode : Penelitian ini menggunakan metode kualitatif dimana setiap data dikumpulkan melalui wawancara,  observasi dan dokumentasi lalu dianalisis untuk menarik kesimpulan.

Hasil : Berdasarkan hasil analisis dapat disimpulkan bahwa sistem pengendalian manajemen pada PT Nauli Sawit sudah baik karena jelasnya pendelegasian wewenang dan tanggung jawab yang diberikan kepada setiap karyawan sehingga dapat meningkatkan kinerja karyawan dan produktivitas pada perusahaan.

Kesimpulan : Penerapan sistem pengendalian manajemen terhadap kinerja karyawan pada PT Nauli Sawit sudah cukup baik karena adanya pendelegasian wewenang dan tanggung jawab yang diberikan pada tiap manajer sehingga dapat meningkat kinerja karyawan.
EFFECT OF AGOMELATINE AND SERTRALINE ON PATIENTS WITH MAJOR DEPRESSIVE DISORDERS AND CHRONIC KIDNEY DISEASE: A RANDOMIZED CONTROLLED TRIAL
Authors: A-Hamad Saleh-Arong Fadhil , Chokemaitree Nattaphon , Nata Naowanit , Tasanavipas Pamila , Varothai Narittaya , Satirapoj Bancha
Published: October 2022

Background: Depression is highly prevalent and is well known to affect patients with chronic kidney disease (CKD). Agomelatine exerts psychotropic effects upon mood and anxious states. There is limited data on agomelatine treatment among patients with CKD.

Methods: Patients with CKD stage 3-5 with DSM-5-defined major depressive disorder (MDD) were randomly assigned to receive 25 mg/day of agomelatine or sertraline 50 mg/day for eight weeks at Phramongkutklao Hospital. Hamilton Depression Rating Scale (HDRS) score and concerning adverse events were measured at baseline and the end of the study. Efficacy assessment compared the improvements in clinical response and remission between the agomelatine and placebo groups.

Results: Of 53 enrolled patients, 27 were assigned to the agomelatine group and 26 to the sertraline group. The mean age was 64.8±13.4 years. Baseline characteristics were comparable across treatment groups. After eight weeks, agomelatine-treated showed reductions in HDRS score from baseline (-15.6 with 95% CI -18.6 to -12.5). A significant difference was observed in the reduced HDRS scores between agomelatine and sertraline groups (-12.4; 95% CI -18.4 to -6.5). Over the 6-week treatment period, clinical response (55.0 vs. 9.0%, p <0.001) and remission (45.0 vs. 17.4%, p =0.049) improved significantly more with agomelatine than with sertraline. Both agomelatine and sertraline were well-tolerated during the treatment period.

Conclusion: Agomelatine showed superior antidepressant efficacy over sertraline in treating CKD patients with depression after eight weeks, with a good tolerability profile.
Penerapan Poin 2.3 Sustainable Development Goals dalam Program Tanjungsari Agro Culture PT. Pertamina (Persero) DPPU Adi Sumarmo Boyolali Jawa Tengah
Authors: Endiyanto Yoga Prasetya
Published: October 2022

Tulisan ini membahas program Tanjungsari Agro Culture yang merupakan salah satu program pemberdayaan masyarakat dari PT. Pertamina (Persero) DPPU Adi Sumarmo. Program ini selain ingin menciptakan kemandirian di tingkat kelompok, juga ingin mewujudkan poin 2.3 dalam Sustainable Development Goals (SDGs). Hasilnya diketahui bahwa program Tanjungsari Agro Culture belum memenuhi seluruh indikator di dalam poin 2.3. Keengganan kelompok untuk mengkapitalisasi program, hambatan administrasi, hingga hambatan regenerasi menjadi sebab mengapa hingga saat ini program Tanjungsari Agro Culture belum memiliki dampak ekonomi yang signifikan bagi kelompok.
FARG‘ONA VODIYSIDA O‘SADIGAN BIR YILLIK SHUVOQ TARKIBIDAGI ARTEMIZININ MIQDORINI ANIQLASH
Authors: Abdulloyev Obidjon Shaxabidinovich , Asqarov Ibrohimjon Rahmonovich , Abdulloyev Shaxobidin Xasanboyevich , Fozilova Gavharoy Erkinjonovna , Matamirova Sharifa Akramovna
Published: October 2022

Artemisia annua L. o'simligining turli geografik mintaqalardagi vakillarining tarkibi dunyo olimlari tomonidan o'rganilib kelingan. Lekin O'zbekistonda o`sadigan vakillarining kimyoviy tarkibi hali to`liq o`rganilmagan. Mazkur tadqiqotda O'zbekistonda, xususan, Farg'ona vodiysida o`sadigan bir yillik shuvoq o'simligidan artemizininni ajratib olish va miqdorini aniqlash hamda uni IQ va Mass spektrlari taxlili keltirilgan.
Thuis, goed aan het werk!
Authors: Haver Droeze-van Iersel E.
Published: October 2022

Thuis, goed aan het werk!

Door aandacht voor preventie van arbeid gerelateerde klachten bij thuiswerken kan werkgeversaansprakelijkheid worden voorkomen.
Child Life-Facilitated Coping Support With Adult Patients Undergoing Cardiac Surgery: A Pilot Program
Authors: Piazza Julie , Heering Lindsay , Peters Stefanie L. , White Molly , Baker Michaella , Baello Christina , Schwenzer Claudia , Deeb G. Michael
Published: October 2022

Objective

With little empirically known about the translation of child life services into adult patient populations, the purpose of this pilot project was to explore the feasibility of offering non-pharmacological child life support to adult cardiac surgery patients. Specifically, the aims were to explore the practical feasibility of extending and integrating child life care into this adult healthcare service, as well as the preliminary perceptions of adult patients who participated in the pilot program.

Methods

A pilot program was designed to provide child life care to an initial group of 11 adult patients undergoing cardiac surgery at a large academic medical center in the midwestern United States. Patients were randomized into a control condition consisting of standard pre- and post-cardiac surgery care or an intervention condition that involved five coping support interactions with a Certified Child Life Specialist serving as a “comfort coach.” Patient perceptions were gathered via telephone survey at the conclusion of the study, and insights into practical feasibility were gathered from associated study staff, clinical team members, and leadership to understand stakeholder experiences with the program.

Results

According to the feedback gathered, it appears that Certified Child Life Specialists can be clinically and practically integrated into adult cardiac surgery populations without patient care disruption. Additionally, feedback from program participants suggested that child life services were appreciated and seen as a beneficial component of the cardiac surgery experience.

Conclusion

This study suggests that it is both possible and practical to extend non-pharmacological coping support from Certified Child Life Specialists into adult cardiac surgery care, and this appears to be a desirable service from patient and staff perspectives. Future research is needed to evaluate the effects of child life services on specific outcomes in this population specific to anxiety, pain management and overall patient experience and care satisfaction.

Disclosure Statement:

No potential conflict of interest was reported by the author(s).

Funding Statement:

No funding sources were provided by the author(s).
PERFORMANCE ANALYSIS OF MUTUAL FUNDS IN INDIA
Authors: Virparia Vimla
Published: October 2022

Mutual fund industry has experienced a drastic growth within the past twenty years. Increase within the number of schemes with increased mobilization of funds in the past few years provide benefits to the importance of the Indian mutual funds industry. Mutual funds have а number of schemes within it, such as large cap, Mid cap and Small cap funds, which makes it hard for the investors tо сhооse the best sсheme out of so many available options.This Study specifically focused on the performance analysis of mutual fund schemes based on the Large cap, Mid cap and Small cap,which helps investors to take  decision based on risk and  returns in current  time. These mutual funds individually using different tools such as Annual returns, Standard Deviation, Beta, Shаrрe's Rаtiо,Treynоr's Rаtiо, Jensen's Аlрhа Rаtiо.
STUDY ON MAJOR INVESTMENT PREFERENCES OF INDIAN INVESTORS
Authors: Panchal Nilam , Ajmera Ayush
Published: October 2022

The purpose of this study was to analyse the preferences of investors in the Indian share market and other investment options available in the market. Many factors including risk awareness, investment time horizon, mode of trading, objectives of investment, usage of fundamental & technical analysis before investment, sources of information, etc. which affect the investment decisions are analysed through this research. The study is carried out using only the primary data collected by convenience sampling technique through a survey of 204 respondents from different regions of India but majorly from Gujarat State. Parametric and Non-parametric tests are applied to the data using SPSS software to analyse the effects of different variables. The study concluded that income levels and risk involvement highly affect the investment decision of an investor. Also, the usage of fundamental and technical analysis is important before making any investment. Another big conclusion is that returns are the major objective of maximum investors. Fixed deposit is the most preferred investment option according to the respondents.
THE IMPACT OF MICROFINANCE ON THE MSMES SECTOR
Authors: Shah Snehal , Hingu Jinal
Published: October 2022

Finance for micro, small and medium size enterprises (MSME’S) has been a concern for all stakeholders including entrepreneurs, financial institutions and government organisations. (Charan et al., 2016) The key objective of this present study is to identify various challenges faced by MSME’s in sourcing finance. The Micro Finance Institution has been conducting a variety of services to assist the financial and non- financial needs of the MSME's entrepreneurs including credit, saving, leasing, insurance facilities and training programs. This survey was conducted in Ahmedabad and Mehsana covering a wide range of sectors like jewellers, retailers, metal works, textiles, book shop, tailor and small manufacturing units. The researcher has used both primary and secondary data. The primary data were collected with the help of a questionnaire in the Google form. The sample size of this particular study is 34 respondents. This little research exists that examines the role of financial institutions, banks and microfinance institutions, on the growth of micro, small and medium enterprises in Gujarat, especially Ahmedabad and Mehsana. The study found that the main challenges faced by MSME’s in underutilization are lack of financial awareness and lack of the tools to evaluate projects that need to be implemented by MSME’S.
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНДАҒЫ ЖҰМЫССЫЗДЫҚ МӘСЕЛЕСІ ЖӘНЕ ОНЫ ШЕШУ ЖОЛДАРЫ
Authors: Айгуль Естурлиева , Дамира Жеңісхан , Раушан Мусина
Published: October 2022

Мақалада Қазақстанның экономикалық дамуы үшін адам капиталының  маңызы қарастырылды. Қазіргі кезде мемлекеттің дамуында  зияткерлік әлеует пен инновациялар, жұмыс күшінің өнімділігі, кадрларды кәсіби даярлау, олардың ұтқырлығы аясындағы сұрақтар мемлекеттік деңгейде күн тәртібіндегі  маңызды мәселелер екендігі көрсетілді.

Еңбек ресурстарын бөлу схемасы келтірілген. Қазақстандағы еңбек нарығының кейбір мәселелерін ішкі еңбек көші-қонын құруға бағытталған іс-шаралар аясында шешуге болатындығы атап өтілді. 2017-2019 жылдардағы Қазақстанның еңбек нарығының негізгі индикаторларына талдау жүргізілді. Гендерлік бөліністе жұмыспен қамтылғандардың үлесі анықталды. Нәтижесінде әйелдер мен жастар арасында жұмыссыздықтың пайда болу себептері анықталды. Еңбек нарығын дамыту үшін ұсыныстар берілді.

Қазақстанның экономикалық дамуы үшін адами капитал мен зияткерлік әлеует пен инновацияның маңыздылығын көрсету болып табылады.

Қазақстанның еңбек нарығының негізгі индикаторларына талдау жасау,  жұмыспен қамтылғандардың жасы жынысы бойынша үлесін анықту арқылы әйелдер және жастар  арасындағы жұмыссыздықтың орын алу себептері анықтау.

Қазақстандағы еңбек нарығының дамуы кәсіпорындарды сапалы кадрлармен  қамтамасыз етеді, оның ішінде: әйелдер және жастар  арасындағы жұмыссыздықтың себептерін анықтау тақырыптың өзектілігін көрсетеді.

Әйелдер мен жастар арасындағы жұмыссыздықтың себептері анықталды. Еңбек нарығын дамыту және сапалы жұмыспен қамтамасыз ету бағыттары ұсынылды. Ол үшін жұмыс күшінің дамуын болжаудың ұлттық жүйесін құру; жұмыс берушілер қызметкерлердің білімі мен құзыреттеріне қойылатын талаптарды бекітетін ұлттық біліктілік жүйесін дамыту жөніндегі жұмысты жалғастыру; формальды және нәтижелі жұмыспен қамтуға жәрдемдесу; еңбек делдалдығының тиімді моделін құру секілді ұсыныстар келтірілді.
РЕГУЛИРОВАНИЕ РЫНКА БАНКОВСКОГО КРЕДИТОВАНИЯ: ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ
Authors: Рахметова Айбота
Published: October 2022

В данной статье рассмотрены современные тенденции развития отечественного рынка банковского кредитования, как наиболее развитого сегмента финансового рынка Казахстана. В частности, приводится анализ современных тенденций развития рынка кредитования, его основных инструментов, изучены ключевые проблемы и ограничения, существенно снижающие социально-экономические эффекты. В частности, автором изучены проблемы асимметрии интересов во взаимодействии субъектов банковского сектора с юридическими и физическими лицами (недоступность кредитов для субъектов реального сектора экономики и критическая закредитованность населения); неэффективность и непривлекательность финансовых инструментов и другие. В заключении, автором предложены рекомендации по решению выявленных проблем и дальнейшему развитию рынка банковского кредитования с точки зрения обеспечения позитивных макроэкономических эффектов за счет одновременного удовлетворения интересов государства, банков, субъектов реального сектора и населения посредством совершенствования действующего механизма регулирования.
Studi Kelayakan Investasi Proyek Perumahan Melalui Skema Akuisisi Proyek Mangkrak
Authors: Daryanto Daryanto , Zainusyukur Zainusyukur
Published: October 2022

Di Indonesia backlog kepemilikan rumah masih tinggi. Hal ini memunculkan peluang Investasi di bidang pembangunan proyek perumahan. Namun bisnis secara alami tetap mengandung ketidakpastian dan memunculkan perumahan mangkrak. Hal ini tentunya merupakan peluang investasi alternatif bagi investor untuk mengambil alih pembangunan perumahan tersebut. Hasil analisa menyimpulkan bahwa pengambilalihan proyek Bumi SKM Residence, milik PT NYG layak untuk dilakukan dengan syarat pembangunan dan penjualan proyek perumahan harus selesai dalam jangka waktu kurang dari tiga tahun. Faktor-faktor lain yang perlu mendapatkan perhatian diantaranya faktor internal: investor perlu effort untuk merubah kesan atas perumahan lama dan perlu mengurus dan memperbaharui perijinan. Faktor-faktor eksternal yang berpengaruh diantaranya: Proyek memiliki keuntungan dengan adanya morotarium pengeluaran ijin baru di Kab Cianjur, tekanan ekonomi di tahun 2019 dan kebijakan pemerintah terkait perumahan yang kerap berubah setiap tahun.
Potential pharmacological Therapeutics options for COVID-19: Review
Authors:   Department of Pharmaceutical Chemistry, alkhawaldeh ahmad ,   College of Pharmacy, Jerash University, Jordan
Published: October 2022

Unusual pneumonia result from unknown pathogen was emerged in December 2019 in a seafood market of Wuhan city in China. The pathogen was soon identified as a novel coronavirus (2019-nCoV), which is closely related to sever acute respiratory syndrome CoV (SARS-CoV) which has taken the world to the edge of health emergency. On 11th March 2020, COVID-19 was declared a pandemic by the World Health Organization. SARS-CoV-2 belongs to the family of Coronaviridae. Corona virus has been reported to cause similar morbific impacts on the lower respiratory system. Transmits occurs when people breathe in air contaminated by droplets and small airborne particles. Transmission can also occur if sprayed with contaminated fluids, in the eyes, nose or mouth. People remain contagious for up to 20 days, and can spread the virus even if they do not develop any symptoms. Although this disease primarily targets lungs, damages in other organs, such as heart, kidney, liver, and testis, may occur.
A Study on Career Progression of Women during Covid- 19
Authors: A.Manojkumar  , Adhithya.V
Published: October 2022

The COVID-19 pandemic situation is harming the health, social and economic well-being worldwide, and with women at the centre. First and foremost of women are major leading the health response: women structure almost 70% of the health care workforce, exposing them to a greater risk of infection. At an equivalent time, women also are shouldering much of the burden reception, given school and child care facility closures and longstanding gender inequalities in unpaid work. And the women also faced high risks of job and income loss, and face increased risks of violence, and exploitation, abuse or harassment during times of crisis and quarantine. Policy responses must be immediate, which they need to account for women’s concerns. Governments should consider adopting emergency measures to help parents manage work and caring responsibilities, reinforcing and increasing income support measures, expanding support for small businesses and thus the self-employed, and improving measure to assist women victims of violence. Finally, all the rules and policy responses to the crisis must embed a gender lens and account for women’s unique needs, responsibilities and perspectives.
The Influence of Market Orientation, Entrepreneurial Orientation, Knowledge Management and Learning Organization on Performance Mediated by Innovation in Culinary SME’s in Bekasi
Authors: M Fadhli Nursal  , Muhammad Richo Rianto  , Eri Bukhari
Published: October 2022

This study aims to see the effect of innovation mediation that connects market orientation, entrepreneurial orientation, knowledge management and organization learning on the performance of MSMEs in the city of North Bekasi. This study uses a quantitative. The unit of analysis in this study is the Culinary SMEs in North Bekasi. This research was conducted on 231 respondents spread across northern Bekasi and used the SmartPLS 3.3.3 statistical tools. The results of this study further emphasize that innovation can mediate the relationship between market orientation and performance. In addition, entrepreneurial orientation also affects performance mediated by innovation and knowledge management affects performance mediated by innovation but organizational learning has no effect on performance mediated by innovation in UMKM culinery in North Bekasi.