bluuebunny/crossref_metadata_2025 huggingface dataset:
A Scoping Review on GIS Technologies Applied to Farmed Fish Health Management
Authors: Dorotea Tiziano , Riuzzi Giorgia , Franzago Eleonora , Posen Paulette , Tavornpanich Saraya , Di Lorenzo Alessio , Ferroni Laura , Martelli Walter , Mazzucato Matteo , Soccio Grazia , Segato Severino , Ferrè Nicola
Published: November 2023

Finfish aquaculture, one of the fastest growing intensive sectors worldwide, is threatened by numerous transmissible diseases that may have devastating impacts on its economic sustainability. This review (2010–2022) used a PRISMA extension for scoping reviews and a text mining approach to explore the extent to which geographical information systems (GIS) are used in farmed fish health management and to unveil the main GIS technologies, databases, and functions used to update the spatiotemporal data underpinning risk and predictive models in aquatic surveillance programmes. After filtering for eligibility criteria, the literature search provided 54 records, highlighting the limited use of GIS technologies for disease prevention and control, as well as the prevalence of GIS application in marine salmonid farming, especially for viruses and parasitic diseases typically associated with these species. The text mining generated five main research areas, underlining a limited range of investigated species, rearing environments, and diseases, as well as highlighting the lack of GIS-based methodologies at the core of such publications. This scoping review provides a source of information for future more detailed literature analyses and outcomes to support the development of geospatial disease spread models and expand in-field GIS technologies for the prevention and mitigation of fish disease epidemics.
Cattle Body Detection Based on YOLOv5-EMA for Precision Livestock Farming
Authors: Hao Wangli , Ren Chao , Han Meng , Zhang Li , Li Fuzhong , Liu Zhenyu
Published: November 2023

Accurate cattle body detection is crucial for precision livestock farming. However, traditional cattle body detection methods rely on manual observation, which is both time-consuming and labor-intensive. Moreover, computer-vision-based methods suffer prolonged training times and training difficulties. To address these issues, this paper proposes a novel YOLOv5-EMA model for accurate cattle body detection. By incorporating the Efficient Multi-Scale Attention (EMA) module into the backbone of YOLO series detection models, the performance of detecting smaller targets, such as heads and legs, has been significantly improved. The Efficient Multi-Scale Attention (EMA) module utilizes the large receptive fields of parallel sub-networks to gather multi-scale spatial information and establishes mutual dependencies between different spatial positions, enabling cross-spatial learning. This enhancement empowers the model to gather and integrate more comprehensive feature information, thereby improving the effectiveness of cattle body detection. The experimental results confirm the good performance of the YOLOv5-EMA model, showcasing promising results across all quantitative evaluation metrics, qualitative detection findings, and visualized Grad-CAM heatmaps. To be specific, the YOLOv5-EMA model achieves an average precision (mAP@0.5) of 95.1% in cattle body detection, 94.8% in individual cattle detection, 94.8% in leg detection, and 95.5% in head detection. Moreover, this model facilitates the efficient and precise detection of individual cattle and essential body parts in complex scenarios, especially when dealing with small targets and occlusions, significantly advancing the field of precision livestock farming.
Dimensional Transitions in Turbulence: The Effects of Rotation and Stratification
Authors: Boffetta Guido
Published: November 2023

The transition from two-dimensional to three-dimensional turbulence is a fascinating problem which finds applications in the study of geophysical flows. This paper briefly reviews the research in this field with emphasis on the role of rotation and stratification, two important ingredients of geophysical flows at large scales. By means of direct numerical simulations of the Navier–Stokes equations, the conditions for the emergence of a split cascade, with a simultaneous cascade of energy to both the large and the small scales, are discussed.
Numerical Model of Filtration Efficiency Based on Fractal Characteristics of Particulate Matter and Particle Filter
Authors: Liu Yiqing , Wang Hao , Yu Haisheng
Published: November 2023

Fractal theory was used to characterize particles and particle trapping parameters to accurately predict the particle filtration process inside a gasoline engine particle filter (GPF). The particles were fractal aggregates, and the fractal dimension (Df) was introduced to redefine the particle size. The porous medium inside the particle filter was a solid phase fractal. The pore tortuosity fractal dimension (Dt) and the pore area fractal dimension (Da) were introduced to define the fiber length of the trap. The Brownian diffusion coefficient and permeability were modified. A new fractal numerical model of GPF filtration efficiency was proposed based on the classical filtration theory. The results show that the fractal expansion model of filtration efficiency has good applicability. The influence of GPF structural parameters on filtration efficiency and pressure drop was analyzed. In this study, two performance metrics, trapping efficiency and pressure drop, were considered by fractal expansion filtration modeling. It is possible to increase or decrease filtration efficiency by adjusting the porosity and pore diameter.
Modeling Silicon-Dominant Anodes: Parametrization, Discussion, and Validation of a Newman-Type Model
Authors: Durdel Axel , Friedrich Sven , Hüsken Lukas , Jossen Andreas
Published: November 2023

Silicon is a promising anode material and can already be found in commercially available lithium-ion cells. Reliable modeling and simulations of new active materials for lithium-ion batteries are becoming more and more important, especially regarding cost-efficient cell design. Because literature lacks an electrochemical model for silicon-dominant electrodes, this work aims to close the gap. To this end, a Newman p2D model for a lithium-ion cell with a silicon-dominant anode and a nickel-cobalt-aluminum-oxide cathode is parametrized. The micrometer silicon particles are partially lithiated to 1200 mAh gSi−1. The parametrization is based on values from the electrode manufacturing process, measured values using lab cells, and literature data. Charge and discharge tests at six different C-rates up to 2C serve as validation data, showing a root-mean-squared error of about 21 mV and a deviation in discharge capacity of about 1.3%, both during a 1 C constant current discharge. Overall, a validated parametrization for a silicon-dominant anode is presented, which, to the best of our knowledge, is not yet available in literature. For future work, more in-depth studies should investigate the material parameters for silicon to expand the data available in the literature and facilitate further simulation work.
Renewal of Scope for Biomass
Authors: Rosendahl Lasse
Published: November 2023

Biomass was started in 2021 with the aim of providing an open access platform for scientific communications within the field of biomass and its uses [...]
BZD9L1 Differentially Regulates Sirtuins in Liver-Derived Cells by Inducing Reactive Oxygen Species
Authors: Lee Yeuan Ting , Tan Yi Jer , Oon Chern Ein
Published: November 2023

Growing evidence has highlighted that mitochondrial dysfunction contributes to drug-induced toxicities and leads to drug attrition and post-market withdrawals. The acetylation or deacetylation of mitochondrial proteins can affect mitochondrial functions as the cells adapt to various cellular stresses and other metabolic challenges. SIRTs act as critical deacetylases in modulating mitochondrial function in response to drug toxicity, oxidative stress, reactive oxygen species (ROS), and energy metabolism. We previously showed that a recently characterised SIRT inhibitor (BZD9L1) is non-toxic in rodents in a short-term toxicity evaluation. However, the impact of BZD9L1 on mitochondrial function is unknown. This work aims to determine the effects of BZD9L1 on mitochondrial function in human normal liver and kidney-derived cell lines using the Agilent Seahorse Cell Mito Stress Test to complement our short-term toxicity evaluations in vivo. The Mito Stress assay revealed that BZD9L1 could potentially trigger oxidative stress by inducing ROS, which promotes proton leak and reduces coupling efficiency in liver-derived THLE cells. However, the same was not observed in human kidney-derived HEK293 cells. Interestingly, BZD9L1 had no impact on SIRT3 protein expression in both cell lines but affected SOD2 and its acetylated form at 72 h in THLE cells, indicating that BZD9L1 exerted its effect through SIRT3 activity rather than protein expression. In contrast, BZD9L1 reduced SIRT1 protein expression and impacted the p53 protein differently in both cell lines. Although BZD9L1 did not affect the spare respiratory capacity in vitro, these findings call for further validation of mitochondrial function through assessment of other mitochondrial parameters to evaluate the safety of BZD9L1.
Intracellular Major Histocompatibility Complex Class II and C-X-C Motif Chemokine Ligand 10-Expressing Neutrophils Indicate the State of Anti-Tumor Activity Induced by Bacillus Calmette–Guérin
Authors: Takeda Yuji , Kato Tomoyuki , Sabrina Saima , Naito Sei , Ito Hiromi , Emi Naoto , Kuboki Yuya , Takai Yuki , Fukuhara Hiroki , Ushijima Masaki , Narisawa Takafumi , Yagi Mayu , Kanno Hidenori , Sakurai Toshihiko , Nishida Hayato , Araki Akemi , Shimotai Yoshitaka , Nagashima Mikako , Nouchi Yusuke , Saitoh Shinichi , Nara Hidetoshi , Tsuchiya Norihiko , Asao Hironobu
Published: November 2023

(1) Background: Inflammatory responses induce the formation of both anti-tumor and pro-tumor neutrophils known as myeloid-derived suppressor cells (MDSCs). Intermittent intravesical infusion of Bacillus Calmette–Guérin (BCG) is an established cancer immunotherapy for non-muscle-invasive bladder cancer (NMIBC). However, the types of neutrophils induced via the inflammatory response to both tumor-bearing and BCG remain unclear. (2) Methods: We therefore analyzed neutrophil dynamics in the peripheral blood and urine of patients with NMIBC who received BCG therapy. Further, we analyzed the effects of BCG in a mouse intraperitoneal tumor model. (3) Results: BCG therapy induced the formation of CXCL10 and MHC class II-positive neutrophils in the urine of patients with NMIBC but did not induce MDSC formation. CXCL10- and MHC class II-expressing neutrophils were detected in peritoneal exudate cells formed after BCG administration. Partial neutrophil depletion using an anti-Ly6G antibody suppressed the upregulation of CXCL10 and MHC class II in neutrophils and reversed the anti-tumor activity of BCG in mouse models. (4) Conclusions: These results indicated that intracellular MHC class II- and CXCL10-expressing neutrophils indicate the state of anti-tumor activity induced via BCG. The status of neutrophils in mixed inflammation of immunosuppressive and anti-tumor responses may therefore be useful for evaluating immunological systemic conditions.
Associations between Single Nucleotide Polymorphisms from the Genes of Chemokines and the CXCR2 Chemokine Receptor and an Increased Risk of Endometrial Cancer
Authors: Wujcicka Wioletta , Zając Agnieszka , Szyłło Krzysztof , Romanowicz Hanna , Smolarz Beata , Stachowiak Grzegorz
Published: November 2023

Significant relationships with endometrial cancer were demonstrated, both for CCL2, CCL5, and CXCL8 chemokines and for the chemokine receptor CXCR2. The reported case-control study of genetic associations was designed to establish the role of selected single nucleotide polymorphisms (SNPs) of the CCL2, CCL5, CXCL8, and CXCR2 genes in the onset and progression of endometrial cancer. This study was conducted on 282 women, including 132 (46.8%) patients with endometrial cancer and 150 (53.2%) non-cancerous controls. The genotypes for CCL2 rs4586, CCL5 rs2107538 and rs2280789, CXCL8 rs2227532 and −738 T>A, and CXCR2 rs1126580 were determined, using PCR-RFLP assays. The AA homozygotes in CCL5 rs2107538 were associated with more than a quadruple risk of endometrial cancer (p ≤ 0.050). The GA heterozygotes in the CXCR2 SNP were associated with approximately threefold higher cancer risk (p ≤ 0.001). That association also remained significant after certain adjustments, carried out for age, diabetes mellitus, arterial hypertension, or endometrial thickness above 5 mm (p ≤ 0.050). The A-A haplotypes for the CCL5 polymorphisms and T-A-A haplotypes for the CCL2 and CCL5 SNPs were associated with about a twofold risk of endometrial cancer (p ≤ 0.050). In conclusion, CCL2 rs4586, CCL5 rs2107538 and rs2280789, and CXCR2 rs1126580 demonstrated significant associations with an increased risk of endometrial cancer.
Treatment Outcomes and Risk Factors for Incomplete Treatment after Definitive Chemoradiotherapy for Non-Resectable or Metastatic Esophageal Cancer
Authors: Pai Chu-Pin , Chien Ling-I , Huang Chien-Sheng , Hsu Han-Shui , Hsu Po-Kuei
Published: November 2023

Among patients with unresectable or metastatic esophageal cancer who receive definitive chemotherapy or chemoradiotherapy, the rates of treatment-related adverse events and incomplete treatment remain high. We conducted this study to investigate survival after definitive treatments and identify predicting factors for incomplete treatment. The data of patients who received definitive chemotherapy or chemoradiotherapy for esophageal cancer were retrospectively examined. The patients were assigned to Group 1: incomplete definitive treatment; Group 2: complete definitive treatment; or Group 3: complete definitive treatment with additional salvage surgery. The data of 273 patients (90, 166, and 17 in Groups 1, 2, and 3, respectively) were analyzed. In the survival analysis, the median overall survival of Groups 1, 2, and 3 were 2.6, 10.3, and 29.5 months, respectively. A significant difference in 3-year overall survival was observed among the groups (2.2%, 12.4%, and 48.5%, p < 0.001). In multivariable analysis, the independent risk factors for incomplete definitive treatment included poor performance score (hazard ratio (HR): 5.23, p = 0.001), bone metastasis (HR: 2.18, p = 0.024), airway invasion (HR: 2.90, p = 0.001), and liver cirrhosis (HR: 3.20, p = 0.026). Incomplete definitive treatment is associated with a far worse prognosis. Poor performance, bone metastasis, airway invasion, and liver cirrhosis are risk factors for incomplete treatment.
Self-Renewal Inhibition in Breast Cancer Stem Cells: Moonlight Role of PEDF in Breast Cancer
Authors: Gil-Gas Carmen , Sánchez-Díez Marta , Honrubia-Gómez Paloma , Sánchez-Sánchez Jose Luis , Alvarez-Simón Carmen B. , Sabater Sebastia , Sánchez-Sánchez Francisco , Ramírez-Castillejo Carmen
Published: November 2023

Breast cancer is the leading cause of death among females in developed countries. Although the implementation of screening tests and the development of new therapies have increased the probability of remission, relapse rates remain high. Numerous studies have indicated the connection between cancer-initiating cells and slow cellular cycle cells, identified by their capacity to retain long labeling (LT+). In this study, we perform new assays showing how stem cell self-renewal modulating proteins, such as PEDF, can modify the properties, percentage of biomarker-expressing cells, and carcinogenicity of cancer stem cells. The PEDF signaling pathway could be a useful tool for controlling cancer stem cells’ self-renewal and therefore control patient relapse, as PEDF enhances resistance in breast cancer patient cells’ in vitro culture. We have designed a peptide consisting of the C-terminal part of this protein, which acts by blocking endogenous PEDF in cell culture assays. We demonstrate that it is possible to interfere with the self-renewal capacity of cancer stem cells, induce anoikis in vivo, and reduce resistance against docetaxel treatment in cancer patient cells in in vitro culture. We have also demonstrated that this modified PEDF protein produces a significant decrease in the percentage of expressed cancer stem cell markers.
ASPP2 Is Phosphorylated by CDK1 during Mitosis and Required for Pancreatic Cancer Cell Proliferation
Authors: Xiao Yi , Chen Yuanhong , Chen Jianan , Dong Jixin
Published: November 2023

(1) Background: pancreatic cancer is highly lethal. The role of apoptosis-stimulating protein of p53-2 (ASPP2) in this lethal disease remains unclear. This protein belongs to the ASPP family of p53 interacting proteins. Previous studies in this lab used phosphate-binding tag (Phos-tag) sodium dodecyl sulfate (SDS) polyacrylamide gels and identified a motility upshift of the ASPP family of proteins during mitosis. (2) Purpose: this study expands on previous findings to identify the detailed phosphorylation regulation of ASPP2 during mitosis, as well as the function of ASPP2 in pancreatic cancer. (3) Methods: the Phos-tag technique was used to investigate the phosphorylation mechanism of ASPP2 during mitosis. Phospho-specific antibodies were generated to validate the phosphorylation of ASPP2, and ASPP2-inducible expression cell lines were established to determine the role of ASPP2 in pancreatic cancer. RNA sequencing (RNA-Seq) was used to uncover the downstream targets of ASPP2. (4) Results: results demonstrate that ASPP2 is phosphorylated during mitosis by cyclin-dependent kinase 1 (CDK1) at sites S562 and S704. In vitro and in vivo results show that ASPP2 is required for pancreatic cancer growth. Furthermore, the expressions of yes-associated protein (YAP)-related genes are found to be dramatically altered by ASPP2 depletion. Together, these findings reveal the phosphorylation mechanism of ASPP2 during mitosis. Collectively, results strongly indicate that ASPP2 is a potential target for abating tumor cell growth in pancreatic cancer.
High-Lead Glazed Ceramic Production in Western Iberia (Gharb al-Andalus) between the 10th and Mid-13th Centuries: An Approach from the City of Évora (Portugal)
Authors: Camara Carlos Andrés , Gonçalves María José , Mirão José Antonio Paulo , Martínez Susana Gómez , Beltrame Massimo
Published: November 2023

In the present study an archaeometry programme has been developed on a limited number of coarse wares, monochrome, and bichrome glazed ceramics retrieved in the cities of Évora, Mértola, and Silves, located in Western Iberia, Portugal (Gharb al-Andalus during the Islamic period). The goals were to shed light on glazed ceramics provenance, technology, trading, and on the glaze technology applied. For this purpose, a multi-analytical approach was employed to characterize ceramic pastes and glazes using optical microscopy (OM), X-ray diffraction (XRD), X-ray fluorescence (XRF), and a Scanning Electron Microscope coupled to an Energy Dispersive Spectrometer (SEM-EDS). Results evidenced that over the Islamic rule, coarse wares were locally produced at Évora. On the contrary, monochrome and bichrome glazed ceramics were imported from the city of Silves, Mértola, and from unidentified workshops, probably located in southern Iberia. The analysis of decorations evidenced that despite the provenance of the samples, the glaze technology applied was rather uniform over time, depicting a widespread technological transfer in the al-Andalus.
Effects of Smartphone Activities on Postural Balance in Adolescents with Intellectual Disabilities
Authors: Jouira Ghada , Alexe Cristina Ioana , Herlo Julien Narcis , Moraru Cristina Elena , Bogdan Mihaela , Alexe Dan Iulian , Mareș Gabriel , Sahli Sonia
Published: November 2023

Considering the rising prevalence of smartphone usage among adolescents with intellectual disabilities and their frequent motor challenges, understanding its impact on their physical well-being is important. This study aims to investigate the impact of smartphone activities on postural balance in adolescents with intellectual disabilities. Two groups of adolescents participated in the study: an intellectual disability group (IDG) (n = 16) and atypical development group (TDG) (n = 12). Static postural balance, using a stabilometric platform on firm and foam surfaces, and dynamic balance, using the Timed Up-and-Go Test (TUGT), were performed under various conditions, such as playing a game, watching videos, video calls, and listening to music. The center of pressure (CoP) values significantly increased (p < 0.05) during all smartphone activities (except listening to music) compared to the control condition in both groups, with the IDG demonstrated a more pronounced increase (p < 0.05) during playing video games and video calls on the firm surface. TUGT scores significantly increased (p < 0.05) during smartphone activities, with greater changes observed in the IDG (p < 0.05), and significantly decreased (p < 0.01) during listening to music in both groups. Our study suggests that adolescents with intellectual disabilities need special tools and guidance to ensure their safety and well-being when using smartphones.
Editorial for “Asthma and Its Impact in Adolescents” Special Issue
Authors: Dal Negro Roberto W.
Published: November 2023

Bronchial asthma is a chronic disease related to the atopic condition in most cases but also to other factors (such as infectious diseases; social, economic, environmental, and occupational conditions; exposure to biological irritants; and/or chemical aggressions) [...]
The Effect of Saffron Kozanis (Crocus sativus L.) Supplementation on Weight Management, Glycemic Markers and Lipid Profile in Adolescents with Obesity: A Double-Blinded Randomized Placebo-Controlled Trial
Authors: Kotanidou Eleni P. , Tsinopoulou Vasiliki Rengina , Giza Styliani , Ntouma Stergianna , Angeli Chrysanthi , Chatziandreou Michail , Tsopelas Konstantinos , Tseti Ioulia , Galli-Tsinopoulou Assimina
Published: November 2023

Global rates of adolescent obesity have led the World Health Organization to consider the disease a pandemic that needs focus. In search of new anti-obesity agents, Crocus sativus, popularly known as saffron, is a nutraceutical agent, praised for its beneficial effects. The study aimed to investigate the possible effect of Kozanis saffron administration on weight management of obese prediabetic adolescents. Seventy-four obese prediabetic adolescents participated in a double-blind placebo-controlled trial of three arms, randomly assigned to receive either Kozanis saffron (n = 25, 60 mg/day), metformin (n = 25, 1000 mg/day) or a placebo (n = 24), for twelve weeks. Anthropometry, glycemic markers and lipid profiles were investigated at baseline and post-intervention. Saffron supplementation significantly reduced the weight z-score, BMI, BMI z-score and waist circumference (WC) of obese adolescents; however, this reduction was less significant compared to the effect of metformin. Metformin administration offered a significantly more profound improvement in anthropometry compared to saffron administration. Saffron administration also provided significant improvements in weight, weight z-scores, BMI values, BMI z-scores and WCs compared to the placebo. Saffron supplementation failed to change any glycemic marker, but provided a significant reduction in fasting triglyceride levels and also a significant increase in fasting HDL levels. Saffron Kozanis constitutes a promising nutraceutical option for adolescents and children with obesity and prediabetes in need of weight management.
Risk Behaviors among Migrant Adolescents in Italy
Authors: Koumantakis Emanuele , Comoretto Rosanna Irene , Dalmasso Paola , Bersia Michela , Lemma Patrizia , Lazzeri Giacomo , Nardone Paola , Vieno Alessio , Galeotti Tommaso , Berchialla Paola , Charrier Lorena
Published: November 2023

Adolescence is a critical period for engaging in health risk behaviors. Migrant adolescents may face unique challenges due to acculturation stress. This study aims to monitor substance use and problem gambling among migrant adolescents living in Italy. Data from the 2017/18 Health Behavior in School-Aged Children survey in Italy were analyzed. The 18,794 participants included 15-year-olds, categorized as native or migrants, with ethnic backgrounds from Western, Eastern European, or non-Western/non-European countries. Girls had higher smoking rates, while boys exhibited higher prevalence of alcohol-related risk behaviors, cannabis use, and gambling. Boys from Eastern European countries displayed a greater risk of drunkenness (OR: 1.58, 95% CI: 1.06–2.37), particularly in the first generation, while those from Western countries showed a higher risk of multiple substance use (OR: 1.44, 95% CI: 1.05–1.96). Girls from Eastern European and non-Western/non-European countries had a lower risk of alcohol consumption (OR: 0.50, 95% CI: 0.29–0.85; OR: 0.55, 95% CI: 0.33–0.91, respectively). Finally, boys, especially those from Eastern European and non-Western/non-European countries, had a significantly higher risk of problem gambling (OR: 1.83, 95% CI: 1.04–3.22; OR: 2.10, 95% CI: 1.29–3.42, respectively). This disparity was more pronounced in the first generation, possibly due to acculturation challenges and socio-economic factors. Risk behaviors in adolescents are influenced by complex interplays of gender, cultural factors, and migration generation. Preventive strategies should consider these factors to effectively address substance use and gambling in this heterogeneous population.
Electrophoretic Deposition of ZnO-Containing Bioactive Glass Coatings on AISI 316L Stainless Steel for Biomedical Applications
Authors: Heidari Laybidi Farnaz , Bahrami Abbas , Abbasi Mohammad Saeid , Rajabinezhad Mojtaba , Heidari Beni Bahar , Karampoor Mohammad Reza , Mousavi Anijdan S. H.
Published: November 2023

The main objective of this investigation was to study the implications of incorporating zinc oxide nanoparticles into the matrix of a bioactive glass for the bioactivity and structural properties of the deposited coating. ZnO-containing bioactive glass was coated on an AISI 316L stainless steel substrate using the electrophoretic deposition technique. AISI 316L stainless steel is a biomedical grade steel, which is widely used in different biomedical applications. For the electrophoretic deposition, voltages and times were chosen in the range of 15–40 V and 15–120 min, respectively. The microstructure, phase composition, and surface roughness of coated samples were analyzed in this investigation. Moreover, the corrosion behavior and the MTT (mitochondrial activity) of samples were studied. Results showed a uniform distribution of elements such as silicon and calcium, characteristic of bioactive glass 58S5, in the coating as well as the uniform distribution of Zn inside the ZnO-containing samples. The findings showed that the deposited ZnO-containing bioactive glass is a hydrophilic surface with a relatively rough surface texture. The results of the MTT and antibacterial effects showed that the deposited layers have promising cell viability.
Effects and Consequences of an Alkali-Induced Cathodic Environment on Coating Aging
Authors: Pélissier Krystel , Diler Erwan , Dossot Manuel , Carteret Cédric , Vittonato Jean , Castillon François , Fontaine Sylvain , Kerzerho Thierry , Larché Nicolas , Lucas Patrice
Published: November 2023

The use of organic coatings in conjunction with cathodic protection (CP) for buried structures is the usual method for protecting steel against corrosion. When the organic coating loses its protective ability, regardless of the reason, the CP becomes the active protection, leading to a specific local environment. This environment can be characterized by high alkalinity, which can be detrimental for the coated structure, either by weakening the steel–coating interface or by the chemical aging of the coating. Thus, the coating must be compatible with CP and able to sustain aging under an alkaline environment. In this study, the susceptibility to alkaline aging and its consequences in regards to coating performance have been investigated for two commercial coatings used for buried structures—fusion bonded epoxy (FBE) and liquid epoxy (LE)—in free membrane and coated steel configurations. The results showed a clear impact of alkaline aging on the studied LE, leading to a significant reduction in coating resistance and ultimately, failure of the steel–coating interface, whereas the studied FBE remained stable. The presented results relate to a precise formulation of LE and FBE; however, the proposed chemical method appears to be relevant and shows the necessity of considering such specific aging results for coating specifications and improvements.
Tribological Performance and Scuffing Resistance of Cast-Iron Cylinder Liners and Al-Si Alloy Cylinder Liners
Authors: Li Chengdi , Chen Xiao , Liu Hao , Dong Lianjie , Jian Huihua , Wang Jingsi , Du Fengming
Published: November 2023

In order to better determine the applicable working conditions of Al-Si alloy cylinder liners and cast-iron cylinder liners, their tribological performance and scuffing resistance are discussed in this paper. After wear and scuffing tests, it was found that cast-iron cylinder liners had better wear resistance and better scuffing resistance, but poor friction performance. Al-Si alloy cylinder liners had weaker wear resistance and scuffing resistance, but excellent friction performance. The wear mechanism of cast-iron cylinder liners is slight adhesive wear, and they are suitable for traditional fuel engines and turbocharged engines with high load, high power, and high stability. The wear mechanism of Al-Si alloy cylinder liners was a mixture of adhesive wear and abrasive wear, and they are suitable for engines that are lightweight, efficient, and energy-saving, and operate at high speeds.
Pharmacy and Fragrances: Traditional and Current Use of Plants and Their Extracts
Authors: González-Minero Francisco José , Bravo-Díaz Luis , Moreno-Toral Esteban
Published: November 2023

This paper aims to establish a current relationship between pharmaceutical sciences andthe development of perfumes and fragrances, which bring significant economic benefits. For this purpose, historical data are used as a starting point, and galenic, chemical and botanical aspects are discussed in a transversal way. Sources such as Web of Science (WOS) and databases such as Scopus, monographs and various web pages (where scientific–technical documents appear) were used. The results and discussion are based on the selection of the 50 plant species most commonly used in high-quality fragrances. Therefore, this publication should be considered an approach to this subject based on an analysis of a representative sample of data. Some characteristics of perfumes (classification according to the concentration of essential oils and combination of plant extracts) are presented beforehand. The main focus of this work is the botanical and chemical analysis of these described plants, pointing out their common name, correct botanical name, geographical place of origin, used part of the plant and main molecules. The most significant families are aromatic: Rutaceae, Lamiaceae (16.7%) and Apiaceae. The most represented genus is Citrus (with seven species or hybrids). However, it should be noted that natural extracts of good quality natural fragrances may be supplemented with chemically synthesized molecules. Of the 50 botanical species selected, 84% of the extracts have their origin in Tropical Asia, the Middle East and the Mediterranean region. This figure generally coincides with the percentage of medicinal plants (or their extracts) admitted by the European Pharmacopoeia. All parts of a plant (depending on which one it is) can be a source of molecules for the elaboration of these products. The most commonly used parts to obtain extracts are flowers and leaves, a biological circumstance that is explained in this work. In this work, 110 molecules have been found that are part of the essences of perfumes and fragrances; the most frequent are linalool, limonene, 1,8-cineole, eugenol and derivatives, geraniol, vanillin and derivatives, β-caryophyllene, p-cymene, and farnesene and derivatives. However, in order to elaborate a quality perfume, many other molecules must be taken into account, according to the creative experience of the perfumer, which is subject to confidentiality, and chemical analysis according to current legislation, which would avoid fraud, allergy and dermatitis problems.
The Effects of Chlorine Doping on the Thermoelectric Properties of Bi2O2Se
Authors: Li Buda , Li Menglu , Qi Hangbo , Zu Xiaotao , Qiao Liang , Xiao Haiyan
Published: November 2023

In this study, we investigate the effects of chlorine doping on the structural, electronic, and thermoelectric properties of Bi2O2Se by employing density functional theory combined with semiclassical Boltzmann transport theory. It is shown that chlorine doping has significant effects on the electronic structure and thermoelectric properties of Bi2O2Se. As chlorine is incorporated into the selenium sites in Bi2O2Se, additional electrons are acquired, thereby inducing metallic properties in chlorine-doped Bi2O2Se. Meanwhile, Cl doping leads to an increase in the electrical conductivity of Bi2O2Se at room temperature by 25 times (from 358.59 S/cm to 9390 S/cm), and the power factor is enhanced by a factor of 2.12 (from 4.04 mW/mK2 to 12.59 mW/mK2). This study demonstrates that chlorine doping is an effective method to modify the physical properties of Bi2O2Se.
Construction of Energetic Complexes Based on LLM-105 and Transition Metal Cations (Ni, Co, Mn, and Cu)
Authors: Xiao Yiyi , Huang Hui , Guo Jinkun , Yan Mi , Wei Liyuan , Liu Yu , Huang Shiliang , Peng Rufang , Jin Bo
Published: November 2023

Energetic complexes represent a crucial research direction for the design and synthesis of novel energetic materials. In this work, 2,6-diamino-3,5-dinitropyrazine-1-oxide (LLM-105), a significant explosive compound with exceptional comprehensive properties, was selected as the ligand for coordinating with various metal ions. Four novel energetic complexes, Ni(C4H3N6O5)2·DMF (1), Co(C4H3N6O5)2·2DMF (2), Mn(C4H3N6O5)3·3/2DMF (3), and Cu3(C4H2N6O5)3·3DMF (4) were successfully synthesized, and their crystal structures were identified by a single-crystal X-ray diffraction technique. The structural analyses illustrated that LLM-105 can form either a mononuclear metal complex after the deprotonation of one amino group or a trinuclear metal complex after the deprotonation of two amino groups. Compound 1 exhibits a planar quadrilateral geometry, while both compounds 2 and 3 display distorted octahedral configurations. Compound 4 has three metal centers and exhibits two coordination configurations of distorted tetragonal pyramid geometry and planar quadrilateral geometry. The detonation performances of compounds 1–4 were also theoretically calculated, revealing their favorable explosive properties. These findings emphasize the diverse coordination modes of LLM-105 and the structural variability and adjustability of its complexes, offering valuable insights for regulating both the structure and performance of the LLM-105 complex as well as researching its deprotonation.
Decapods of the Southern Tip of South America and the Marine Protected Area Namuncurá–Burdwood Bank: A Nearshore–Offshore Comparison
Authors: Di Salvatore Pablo , Albano Mariano J. , Diez Mariano J. , Tapella Federico , Pérez-Barros Patricia , Lovrich Gustavo A.
Published: November 2023

The Marine Protected Area (MPA) Namuncurá−Burdwood Bank was created in 2013 to protect the benthic community. After five years of multidisciplinary research, it was reorganized, and a second, contiguous MPA Namuncurá−Burdwood Bank II was created. The objectives of this study were to evaluate the decapod assemblages in both the previous and current management zones and to compare them with the neighboring areas of southern South America. The decapod fauna was studied integratively by comparing captured species onboard scientific expeditions with online records. Our study showed that the original design of the MPAN−BB had the lowest decapod species richness. However, the constitution of a larger protected area, including the slope, increased the species richness, with unique records of Campylonotus arntzianus and Lithodes couesi. The MPA could be considered ecologically representative as it shares various species with the nearby areas (the Beagle Channel and the Atlantic). Furthermore, we theorize it could act as a “hub” for decapod species as marine currents provide the Burdwood Bank with new individuals from the west and disperse them northward to the Patagonian Shelf and eastward to the Scotia Arc. This result shows the great value of protecting this area, ensuring the conservation of the decapod fauna of southern South America.
ChatGPT across Arabic Twitter: A Study of Topics, Sentiments, and Sarcasm
Authors: Al-Khalifa Shahad , Alhumaidhi Fatima , Alotaibi Hind , Al-Khalifa Hend S.
Published: November 2023

While ChatGPT has gained global significance and widespread adoption, its exploration within specific cultural contexts, particularly within the Arab world, remains relatively limited. This study investigates the discussions among early Arab users in Arabic tweets related to ChatGPT, focusing on topics, sentiments, and the presence of sarcasm. Data analysis and topic-modeling techniques were employed to examine 34,760 Arabic tweets collected using specific keywords. This study revealed a strong interest within the Arabic-speaking community in ChatGPT technology, with prevalent discussions spanning various topics, including controversies, regional relevance, fake content, and sector-specific dialogues. Despite the enthusiasm, concerns regarding ethical risks and negative implications of ChatGPT’s emergence were highlighted, indicating apprehension toward advanced artificial intelligence (AI) technology in language generation. Region-specific discussions underscored the diverse adoption of AI applications and ChatGPT technology. Sentiment analysis of the tweets demonstrated a predominantly neutral sentiment distribution (92.8%), suggesting a focus on objectivity and factuality over emotional expression. The prevalence of neutral sentiments indicated a preference for evidence-based reasoning and logical arguments, fostering constructive discussions influenced by cultural norms. Sarcasm was found in 4% of the tweets, distributed across various topics but not dominating the conversation. This study’s implications include the need for AI developers to address ethical concerns and the importance of educating users about the technology’s ethical considerations and risks. Policymakers should consider the regional relevance and potential scams, emphasizing the necessity for ethical guidelines and regulations.
Micro-Fibrillated Cellulose in Lignin–Phenol–Formaldehyde Adhesives for Plywood Production
Authors: Ahmed Sheikh Ali , Hosseinpourpia Reza , Adamopoulos Stergios
Published: November 2023

Petrochemical-based phenol–formaldehyde (PF) adhesives are widely used in plywood production. To substitute phenol in the synthesis of PF adhesives, lignin can be added due to its structural similarity to phenol. Moreover, micro-fibrillated cellulose (MFC) can further enhance the bond performance, mechanical properties, and toughness of adhesive systems. Thus, the aim of this study was to evaluate the adhesion performance of lignin–PF (LPF) adhesives reinforced with MFC. In LPF formulations, three levels of MFC (0, 15, and 30 wt% based on the total solid content of adhesives) were added to the homogenous adhesive mixture. Three-layer plywood panels from birch (Betula pendula Roth.) veneers were assembled after hot pressing at 130 °C under two pressing durations, e.g., 60 and 75 s/mm. Tensile shear strength was measured at dry (20 °C and 65% RH) and wet conditions (water soaked at room temperature for 24 h). The results indicated that the addition of lignin reduced the strength of LPF adhesives in both dry and wet conditions compared to the control PF adhesive. However, MFC reinforcement enhanced the shear strength properties of the plywood. Furthermore, a longer pressing time of 75 s/mm slightly increased the shear strength.
Effect of Extraction Methods on Aroma Profile, Antioxidant Activity and Sensory Acceptability of Specialty Coffee Brews
Authors: Lapčíková Barbora , Lapčík Lubomír , Barták Petr , Valenta Tomáš , Dokládalová Kateřina
Published: November 2023

Specialty coffees from various geographical origins were processed using different extraction methods. Four extraction techniques were employed: cold brew (CB), espresso (ES), French press (FR), and aeropress (AE). The potential health benefits of coffee brews were linked to their antioxidant activity, as determined by the DPPH assay, and total polyphenol content (TPC) measured through the Folin–Ciocalteu reducing-capacity assay. The Columbia (C) espresso coffee type (omni-roasting) exhibited the highest antioxidant activity (86.31 ± 0.70) μmol/100 mL, with a TPC value of (44.41 ± 0.35) mg GAE/g. Quantitative analyses of caffeine and chlorogenic acid were conducted using high-performance liquid chromatography (HPLC). The evaluation of coffee aroma profiles involved the application of headspace solid-phase microextraction/gas chromatography–mass spectrometry (HS-SPME/GC-MS) and was complemented by sensory analysis following the Specialty Coffee Association (SCA) standard protocol. The predominant volatile compounds found in all samples included furans, phenols, pyrazines, and terpenes. The EY espresso type (medium dark roasting) had the highest levels of most coffee volatiles. The C cold brew type (omni-roasting) was rated as the preferred coffee in terms of its sensory characteristics and flavour. In summary, ES and CB were found to be more effective extraction methods for the parameters assessed.
Antimicrobial Activity of Essential Oils in Vapor Phase In Vitro and Its Application in Combination with Lactic Acid to Improve Chicken Breast Shelf Life
Authors: Rivera de la Cruz Jovany Fortino , Schelegueda Laura Inés , Delcarlo Sofía Belén , Gliemmo María Fernanda , Campos Carmen Adriana
Published: November 2023

The effect of essential oils (EOs) incorporated in their vapor phase combined with lactic acid immersion pretreatment was studied on fresh refrigerated chicken breast shelf life. Among the several EOs assayed, the in vitro results obtained from the vapor diffusion test allowed mustard, oregano, and garlic EOs to be selected due to their higher antimicrobial activity. In addition, it was possible to determine the EO minimum inhibitory concentrations against Pseudomonas aeruginosa and Escherichia coli and to identify EO binary mixtures showing synergistic or additive effects. Based on the obtained results, a ternary mixture constituted by 0.073, 0.292, and 0.146 µL/mL of headspace of mustard, oregano, and garlic, respectively, was proposed for its application to chicken breasts. The ternary mixture inhibitory action was confirmed in vitro against P. aeruginosa and E. coli. Furthermore, the presence of numerous compounds with recognized antimicrobial and antioxidant activity was found in its volatile phase through gas chromatography. When applying an EO mixture in its vapor phase in combination with 1.0% v/v of lactic acid immersion pretreatment on refrigerated chicken breast, a decrease in mesophilic microorganisms’ growth rate as well as in lipid oxidation was observed. Moreover, in a preliminary sensory test, the treated chicken breast was found to be acceptable to consumers and showed no significant differences compared to untreated chicken. In conclusion, the combined use of lactic acid immersion and EOs in their vapor phase was an effective alternative to increase chicken breast shelf life.
The Effect of Germination and Fermentation on the Physicochemical, Nutritional, and Functional Quality Attributes of Samh Seeds
Authors: Mohammed Belal M. , Mohamed Ahmed Isam A. , Alshammari Ghedeir M. , Qasem Akram A. , Yagoub Abu ElGasim A. , Ahmed Mohammed Asif , Abdo Abdullah A. A. , Yahya Mohammed Abdo
Published: November 2023

This study investigated the effects of fermentation and germination on the physicochemical, nutritional, functional, and bioactive quality attributes of samh seeds. Regardless of the processing treatment, samh seeds were found to be a rich source of phenolic compounds, namely gallic acid (79.6–96.36 mg/100 g DW), catechol (56.34–77.34 mg/100 g DW), and catechin (49.15–84.93 mg/100 g DW), and they possessed high DPPH antiradical activity (65.27–78.39%). They also contained high protein content (19.29–20.41%), essential amino acids content (39.07–44.16% of total amino acids), and unsaturated fatty acid content (81.95–83.46% of total fatty acids) and a low glycemic index (39.61–41.43). Fermentation and germination increased L*, b*, foaming capacity, oil absorption capacity (OAC), water absorption capacity (WAC), swelling power, microbial counts, antioxidant activity, total flavonoid content (TFC), total phenolic content (TPC), in vitro protein digestibility, protein efficiency ratio, and total essential amino acids and reduced water solubility, emulsion stability, tannin, and phytate contents compared to raw samh seeds (p < 0.05). The highest levels of pH, ash, carbohydrate, fiber, and glycemic index were observed in raw samh seeds, and both germination and fermentation processes reduced these attributes to various degrees (p < 0.05). Germination increased the redness (a*), moisture content, essential and non-essential amino acids, potassium, zinc, phosphorous, stearic acid, and oleic and unsaturated fatty acids and reduced total solids, fat content, iron, zinc, calcium, magnesium, sodium, palmitic acid, and total saturated fatty acids of the samh seeds compared to the raw ones. Fermentation increased the total solid, acidity, fat, protein, calcium, magnesium, sodium, phosphorous, iron, zinc, palmitic acid, and total saturated fatty acids and reduced the a* value, moisture, non-essential amino acids, and total unsaturated fatty acids of the samh seeds compared to the raw ones. In conclusion, samh seeds are a rich source of nutrients that could generally be enhanced by germination and fermentation processes. The reported information facilitates strategies towards the application of these underutilized seeds in foods.
Bioactive Ingredients for Safe and Health-Promoting Functional Foods
Authors: Vanin Fernanda Maria , de Carvalho Rosemary Aparecida , Dos Santos Garcia Vitor Augusto , Yoshida Cristiana Maria Pedroso
Published: November 2023

A full ingredient or a portion of food utilized as food for specific therapeutic purposes is referred to as a functional food [...]
Genetic Interactions in Various Environmental Conditions in Caenorhabditis elegans
Authors: Toch Katarzyna , Buczek Mateusz , Labocha Marta K.
Published: November 2023

Although it is well known that epistasis plays an important role in many evolutionary processes (e.g., speciation, evolution of sex), our knowledge on the frequency and prevalent sign of epistatic interactions is mainly limited to unicellular organisms or cell cultures of multicellular organisms. This is even more pronounced in regard to how the environment can influence genetic interactions. To broaden our knowledge in that respect we studied gene–gene interactions in a whole multicellular organism, Caenorhabditis elegans. We screened over one thousand gene interactions, each one in standard laboratory conditions, and under three different stressors: heat shock, oxidative stress, and genotoxic stress. Depending on the condition, between 7% and 22% of gene pairs showed significant genetic interactions and an overall sign of epistasis changed depending on the condition. Sign epistasis was quite common, but reciprocal sign epistasis was extremally rare. One interaction was common to all conditions, whereas 78% of interactions were specific to only one environment. Although epistatic interactions are quite common, their impact on evolutionary processes will strongly depend on environmental factors.