bluuebunny/crossref_metadata_2025 huggingface dataset:
Literature Review: The Description of the Stunting Memory Program Evaluation as an Effort to Optimize the Decline in the Stunting Incidence in the Pandemic Covid-19 Era
Authors: Nurahadiyatika Faraiesa , Himmawan M Fikri
Published: December 2022

Background: Stunting is included in the category of chronic nutritional problems in children which is currently a top priority for nutritional problems in Indonesia. The condition of stunting can be described through the nutritional status of under-five during the growth and early development period of life caused by a lack of child nutrition at the age of the golden period or the 1000 HPK period (the first 1000 days of life). The prevalence of stunting in Indonesia reached 24.4% in 2021, which has decreased from 2018, which was 30.8%, this figure is high when compared to the world's stunting prevalence of (21.7%). The stunting prevention and control program (children born shortly) during the Covid-19 pandemic still needs to be reviewed and re-evaluated to optimize efforts to reduce the incidence of stunting.
Objective: Knowing the description of the evaluation of the stunting prevention program as an effort to optimize the reduction in the incidence of stunting in the Covid-19 Pandemic era.
Discussion: This journal article was written with inclusion criteria related to the stunting prevention program from 2021 to 2022 during the Covid-19 pandemic. The focus of the stunting prevention program led to the selection of ten journal articles for review in the writing of this journal article. According to the findings of the literature review, the evaluation of stunting prevention programs during the Covid-19 pandemic was quite good when implemented offline. Directly implemented programs effectively increase understanding of the intended research objectives. The results obtained through the stunting prevention program are aimed at research objectives, namely, the aim is to understand and understand the dangers of stunting in children, how to treat and prevent stunting in children, and how to prepare solid complementary food or healthy complementary food for stunted children.
Conclusion: The health coaching approach to stunting targets uses various educational media and the provision of MP-ASI and PMT, which has been extensively researched, and is considered very effective in increasing public awareness paying attention to health, especially fulfilling nutrition during the Covid-19 pandemic, so that efforts to reduce the incidence rate of stunting can be optimized.
Resenha do livro Música, cultura e sociedade
Authors: Pomar Nira
Published: December 2022

Organizado por André Egg e publicado em 2016 pela editora CRV, o livro Música, cultura e sociedade: dilemas do moderno é uma obra para consulta temática, destinada a estudantes e pesquisadores que buscam se atualizar em relação às pesquisas que vêm sendo realizadas na área da Música. Reúne onze textos, de onze autores e autoras diferentes, que tratam, de maneira geral, das relações de produção e veiculação de música, do século XIX ao século XXI, utilizando os meios de comunicação disponíveis em cada época. Com um olhar crítico, a presente resenha busca destacar os pontos principais de cada um dos textos, que estão divididos em duas partes: Modernismo, instituições, crítica musical e musicologia, composta por cinco textos, e Meios de comunicação, identidades e música brasileira, que reúne outros seis textos.
Intelligent feature extraction, data fusion and detection of concrete bridge cracks: current development and challenges
Authors: Wang Di , Yang Simon X.
Published: December 2022

As a common appearance defect of concrete bridges, cracks are important indices for bridge structure health assessment. Although there has been much research on crack identification, research on the evolution mechanism of bridge cracks is still far from practical applications. In this paper, the state-of-the-art research on intelligent theories and methodologies for intelligent feature extraction, data fusion and crack detection based on data-driven approaches is comprehensively reviewed. The research is discussed from three aspects: the feature extraction level of the multimodal parameters of bridge cracks, the description level and the diagnosis level of the bridge crack damage states. We focus on previous research concerning the quantitative characterization problems of multimodal parameters of bridge cracks and their implementation in crack identification, while highlighting some of their major drawbacks. In addition, the current challenges and potential future research directions are discussed.
The TNNI3 p.R186Q mutation is responsible for hypertrophic cardiomyopathy via promoting FASN-stimulated abnormal fatty acid metabolism
Authors: Guo Linjuan , Su Yuhao , Chen Chen , Zhou Qiongqiong , Shen Yang , Jiang Zhenhong , Yan Xia , Li Xiaoqing , Zhuo Wen , Peng Xiaogang , Wan Rong , Hong Kui
Published: December 2022

Introduction: The TNNI3 gene encodes the protein of cardiac troponin I (cTnI), which is an inhibitory subunit of sarcomeres. Mutations in this gene account for 3% of hypertrophic cardiomyopathy (HCM) and the molecular mechanism is complex. Recently, lipid metabolism has been revealed to be involved in HCM. Aim: The purpose of this work is to identify whether the pathological mechanism of the hotspot mutation TNNI3 p.R186Q in HCM is related to abnormal lipid metabolism. Methods and Results: A knock-in (KI) mouse model carrying the Tnni3 p.R186Q homozygous mutation (Tnni3R186Q/R186Q) was novelty generated by CRISPR/Cas9 technology and successfully constructed a typical phenotype of cardiac-myopathy. Likewise, neonatal rat cardiomyocytes (NRCMs) transfected with a mutant plasmid with the TNNI3 p.R186Q mutation showed the same phenomenon. In-depth experiments on related functions and molecular mechanisms were conducted, and Tnni3R186Q/R186Q mice exhibited abnormal fatty acid metabolism, which was induced by the activation of epidermal growth factor receptor (EGFR)-dependent high expression of fatty acid synthase (FASN) in vivo and in vitro. Specifically, the direct binding of EGFR and cTnI was destroyed by TNNI3 p.R186Q mutation, as observed through bioinformatics, Co-IP and GST-pull down analysis. Conclusion: In the present study, we successfully engineered Tnni3R186Q/R186Q mice with the typical phenotype of myocardial hypertrophy. We demonstrated that the TNNI3 p.R186Q mutation could induce HCM by the dissociation of EGFR and cTnI, which further led to EGFR-dependent increased expression of FASN and abnormal lipid metabolism.
Targeting neutrophil serine proteinases in alpha-1 antitrypsin deficiency
Authors: Chen Celine H. , Stockley Robert A.
Published: December 2022

Alpha-1 antitrypsin (AAT) is the most abundant irreversible serine proteinase inhibitor in the circulation and plays a major role in protecting lung tissue against destruction from neutrophil serine proteinases. Genetic mutation of AAT leads to reduced circulating levels and AAT deficiency (AATD) which is associated with an increased risk of developing emphysema. This observation suggests that the balance between AAT and neutrophil serine proteinase is crucial in maintaining tissue homoeostasis. In AATD, the overexuberant proteinase activity resulting from inadequate AAT control creates a self-perpetuating inflammatory cycle, driving progressive tissue injury. Re-establishing this physiological balance is therefore critical for preserving lung architecture, function, and abrogating disease progression. Several avenues within this pathophysiological pathway are being explored. This chapter addresses the pathophysiological process, current treatments targeting the pathway, and alternative approaches within the pathway that can potentially mitigate proteinase imbalance.
Analysis and Simulation of BER Performance of Chaotic Underwater Wireless Optical Communication Systems
Authors:   JSC Yuzhmorgeologia, Bender O. V. ,   JSC Yuzhmorgeologia, Tarasenko A. A. ,   JSC Yuzhmorgeologia, Samonova Ch. V. ,   JSC Yuzhmorgeologia, Semernik I. V.
Published: December 2022

It is shown that modulation methods based on the phenomenon of dynamic chaos and correlation processing can improve the noise immunity of underwater wireless communication systems. This provides the possibility of signal recovery at negative values of the signal-to-noise
TRABALHO DE MOTOBOYS INFORMAIS E OS RISCOS À SAÚDE DURANTE A PANDEMIA DE COVID-19
Authors: Calabrez Nicole , Baracho de Alencar Maria do Carmo
Published: December 2022

O objetivo deste estudo foi o de compreender os modos de organização e as condições de trabalho de motoboys informais de aplicativos, durante a pandemia de COVID-19. Métodos: Seleção de motoboys de aplicativos através de redes sociais, obtenção de dados pessoais, de trabalho e saúde, e realização de entrevistas via Google Meet para análise de conteúdo temática. Resultados: De 13 sujeitos, a maioria do sexo masculino (12), a maioria (9)  referiu a ocorrência de sintomas similares aos da Covid-19, porém sem buscar atendimento médico e diagnóstico no período, além da necessidade de todos de terem que trabalhar para garantir o sustento da família. E destes, participaram das entrevistas 5 motoboys de ambos os sexos. Surgiram nas entrevistas: pouco reconhecimento pelo trabalho, sentimentos de revolta, indignidade e descaso diante das empresas-aplicativos, além do medo e preocupação relacionados à COVID-19,  vulnerabilidade e os riscos à saúde e segurança, indicando precariedade no trabalho. Conclusão: São necessárias intervenções e melhorias das condições de trabalho, além de garantias de direitos trabalhistas.
MULHERES E O TRABALHO TERCEIRIZADO DE HIGIENIZAÇÃO E LIMPEZA NA PANDEMIA DE COVID-19
Authors: De Siqueira Brahm Maitê , Acosta de Medeiros Mara Rosange
Published: December 2022

O presente artigo tem como objetivo analisar qual o impacto da pandemia de COVID-19 na saúde mental de trabalhadoras terceirizadas em contratos de higienização e limpeza em instituições federais de ensino (IFES) no estado do Rio Grande do Sul. Esse tipo de atividade laboral é atravessado pela precarização das relações de trabalho, o que expõe as trabalhadoras a diversas desigualdades. Para tanto, se faz uso da técnica de métodos mistos, incorporando duas etapas de coleta de dados, uma quantitativa via Google Formulários e outra qualitativa com entrevistas em profundidade via chamada de voz. Os dados apresentam uma piora na saúde mental e física das trabalhadoras de limpeza terceirizadas durante a pandemia. Também permitiram averiguar o aumento na intensidade da jornada de trabalho e o impacto da invisibilização na realidade laboral das trabalhadoras.  Conclui-se que existem interesses na manutenção do trabalho feminino terceirizado, mesmo durante a pandemia de COVID-19, visto que há lucratividade para o Estado e para as empresas terceirizadas. Isso acarreta condições precarizadas e invisibilizadas de trabalho feminino na área de limpeza, ampliando os malefícios sobre a saúde das mulheres.
SINTOMATOLOGIA DE STRESS EM POLICIAIS DA REGIÃO SUL DE MOÇAMBIQUE DURANTE A PANDEMIA DA COVID-19
Authors: Mucavele Bênson Nilton Xai-Xai , Abacar Mussa , Aliante Gildo
Published: December 2022

Este estudo investigou a sintomatologia de stress em 100 agentes da polícia durante a pandemia da Covid-19. Do ponto de vista metodológico, esta investigação, de cariz descritivo, situa-se no enfoque quantitativo. Foram aplicados de forma individual, dois instrumentos distintos: Inventário de Sintomas de Stress para Adultos de Lipp e questionário de dados sociodemográficos e laborais. A análise descritiva dos dados, realizada com auxílio do Software Statistical Package for the Social Sciences, indicou a predominância de sintomas de stress físicos como psicológicos, sobretudo os da fase de resistência. Estes achados reforçam a necessidade de desenho e implementação de políticas institucionais de atenção à saúde do trabalhador centradas no diagnóstico, orientação e controle do stress no trabalho.
PANDEMIA E TRABALHO
Authors: Etges da Rosa Sarah Fernanda , Eduardes Klafke Teresinha
Published: December 2022

O artigo objetiva explorar a relação entre a pandemia, o trabalho e a saúde mental a partir do contexto familiar de oito famílias moradoras de uma cidade do interior do Rio Grande do Sul. A metodologia foi pautada na entrevista semiestruturada e na análise de conteúdo. Ao todo foram entrevistadas nove pessoas, um pai, seis mães e um casal. Os resultados apontaram para o aumento da precariedade e insegurança laboral e pessoal, e para a intensificação das perdas financeiras. O teletrabalho demonstrou a contradição entre os diferentes papéis desenvolvidos pelos responsáveis, a inadequação do espaço doméstico e a sobrecarga dos sujeitos, com as mulheres e as mães sendo as mais afetadas. Além disso, a concepção de entretenimento se modificou, com o trabalho ganhando novas nuances e destaque nesse âmbito, se tornando sinônimo de socialização, distração e normalidade. Quem conseguiu manter atividades laborais precisou se reinventar e, não obstante, manter a qualidade da performance, sustentar a renda e o bem-estar profissional e pessoal. Desse modo, os sentimentos de isolamento, exaustão, ansiedade, estresse e desgaste emocional aumentaram.
Integrating UAS Photogrammetry and Digital Image Correlation for Monitoring of Large Landslides
Authors: Mugnai Francesco , Masiero Andrea , Angelini Riccardo , Cortesi Irene
Published: December 2022

This paper shows the results of applying high-resolution Unmanned Aircraft System (UAS) photogrammetric surveying on a large landslide. A real case study, where permanently installing GCPs could be complex, where natural shaped and formed land pose severe limitations in deploying ground targets with optimal geometric configuration. We analysed performances in terms of survey accuracy obtained by performing photogrammetric surveys through the Zenmuse P1 DJI optical camera and Phantom 4 Pro 2. In combination with DJI Matrice 300 UAS, the P1 camera allows direct georeferencing through GNSS observations in RTK mode. Photogrammetric surveys, performed through different georeferencing methods, have been compared. Several targets have been permanently installed on the ground over the maximum vegetation height to guarantee long-lasting reference over the years in the area, which is characterised by a diffuse short vegetation coverage. Multitemporal UAS surveys have been then compared using Digital Image Correlation (DIC) algorithms, and deformation maps have been produced. Afterwards, DIC results were compared with observations made by the GNSS ground-based permanent receivers resulting in a standard deviation of 0,077 m. Through results analysis, good accordance between ground-based GNSS observations and DIC analysis on the photogrammetric surveys have been identified for the same time span. To conclude, this type of landslide presents a moderate deformation speed; in such a case, effective deformations monitoring could be achieved using pseudo-direct georeferencing, which permitted a 0.24 m accuracy on the whole tested area.
Designing a Renewable and Sustainable Phosphorus Fertilizer Supply Chain Network using an Ensemble Knowledge-based Heuristic-Metaheuristic Algorithm
Authors: Shokouhifar Mohammad , Sohrabi Mahnaz , Rabbani Motahareh , Molana Mohammad , Werner Frank
Published: December 2022

Phosphorus (P) is the most important substance in inorganic fertilizers used in agriculture industry. In this study, a multi-product and multi-objective model is presented considering economic and environmental concerns to design a renewable and sustainable P-fertilizer supply chain management (PFSCM). To handle complexities of the proposed model, an ensemble knowledge-based three-stage heuristic-metaheuristic algorithm utilizing heuristic information available in the model, whale optimization algorithm, and variable neighborhood search (named H-WOA-VNS) is proposed. At first, a problem-dependent heuristic is designed to generate a set of near-optimal feasible solutions. These solutions are fed into a population-based whale optimization algorithm which benefits from both exploration and exploitation strategies. Finally, a single-solution metaheuristic based on variable neighborhood search is applied to further improve the quality of the solution using local search operators. The objective function of the algorithm is formulated as a weighted average function to minimize total economic cost, while increasing crop yield and P use efficiency. Experimental results over five synthetic datasets and a real case study of the P-fertilizer supply chain confirm the superiority of the proposed method against the state-of-the-art techniques. The results demonstrate that the proposed method performs well in optimizing both the economic cost and environmental issues.
Strategies and Challenge of Thick Electrodes for Energy Storage: A Review
Authors: Zheng Junsheng , Xing Guangguang , Jin Liming , Lu Yanyan , Qin Nan , Gao Shansong , Zheng Jim P
Published: December 2022

In past years, lithium-ion batteries (LIBs) can be found in every aspect of life, and batteries, as energy storage systems (ESSs), need to offer electric vehicles (EVs) more competition to be accepted in markets for automobiles. Thick electrode design could reduce the use of non-active materials in batteries that its energy density would be improved and its cost would be cut. However, thick electrodes are limited by their weak mechanical stability and poor electrochemical performance, these limitations could be classified as the critical cracking thickness (CCT) and the limited penetration depth (LPD). The understanding of the CCT and the LPD have been proposed and the recent works on breaking the CCT and improving the LPD are listed in this article. By comprising these attempts, some thick electrodes could not offer higher mass loading or higher accessible areal capacity that would defeat the purpose.
Implementation of Antimicrobial Stewardship in a District Hospital in the Ashanti Region of Ghana Using a Health Partnership Model
Authors: Amponsah Obed Kwabena Offe , Courtenay Aaron J. , Abuelhana Ahmed , Ayisi-Boateng Nana Kwame , Opoku Douglas Anning , Blay Lawrence Kobbina , Abruquah Nana Akua , Osafo Annabella Bensusan , Danquah Charlotte Boachie , Tawiah Phyllis , Opare-Addo Mercy Naa Aduele , Owusu-Ofori Alex , Buabeng Kwame Ohene
Published: December 2022

Commonwealth Partnerships for Antimicrobial Stewardship (AMS) uses a health partnership model to establish AMS in Commonwealth countries. The University Hospital of Kwame Nkrumah University of Science and Technology in partnership with Ulster University, in Northern Ireland undertook an AMS project from November 2021 to May 2022. We report on the implementation and its effect on antibiotic use and infections management at the University Hospital. The Global-Point Prevalence Survey (PPS) protocol was used to assess antibiotics use at the hospital at the beginning, midpoint and end of the project. Feedback on each PPS was given to staff to inform behaviour change and improve antibiotic prescribing. Antibiotic use reduced from 65% at baseline to 59.7% at the end of the project. The rate of health-associated infections also reduced from 17.5% at baseline to 6.5%. In addition, the use of antibiotics belonging to the WHO Access group at the hospital was 40% initially but increased to 50% at the project endpoint. Culture and antibiotic susceptibility requests increased from the beginning of the project from 111 total requests to 330 requests over 7 months. The AMS model implemented improved antibiotic use as well as requests for culture and susceptibility test which must be sustained.
P21 Overexpression Promotes Cell Death and Induces Senescence in Human Glioblastoma
Authors: Mansour Moustafa A. , Rahman Masum , Ayad Ahmed A. , Warrington Arthur E , Burns Terry C.
Published: December 2022

High-grade gliomas are the most common and aggressive adult primary brain tumors with a median survival of only 12-15 months. Current standard therapy consists of maximal safe surgical resection followed by DNA-damaging agents, such as irradiation and chemotherapy that can delay but not prevent inevitable recurrence. Some have interpreted glioma recurrence as evidence of glioma stem cells which persist in a relatively quiescent state after irradiation and chemotherapy, before the ultimate cell cycle re-entry and glioma recurrence. Conversely, latent cancer cells with a therapy-induced senescent phenotype have been shown to escape senescence, giving rise to more aggressive stem-like tumor cells than those present in the original tumor. Therefore, approaches are needed to either eliminate or keep these glioma-initiating cells in a senescent state for a longer time to prolong survival. In our current study, we demonstrate that the radiation-induced cell cycle inhibitor P21 can provide a powerful route to induce cell death in short-term explants of PDXs derived from three molecularly diverse human gliomas. Additionally, cells not killed by P21 overexpression were maintained in a stable senescent state for longer than control cells. Collectively, these data suggest that P21 activation may provide an attractive therapeutic target to improve therapeutic outcomes.
Behind the Curtain: In silico and in vitro Experiments Brought to Light New Insights Into the Anticryptococcal Action of Synthetic Peptides
Authors: Aguiar Tawanny K. B. , Neto Nilton A. S. , Silva Romério R.S. , Freitas Cleverson D. T. , Mesquita Felipe Pantoja , Alencar Luciana Magalhães Rebelo , Santos-Oliveira Ralph , Goldman Gustavo H. , Souza Pedro Filho Noronha
Published: December 2022

Cryptococcus neoformans threaten the health, causing cryptococcal meningitis and pneumonia, especially in immunosuppressed patients, which can be fatal. Recently, our research group evaluated and studied the mechanisms of action of four synthetic peptides (SP) against C. neoformans. Here, in silico and in vitro analyses help deepen understanding of peptides' mechanisms of action. The interaction of the peptides with a membrane receptor was analyzed by docking analysis, in addition to ROS overproduction and the modulation of redox metabolism, inhibition of ergosterol biosynthesis, and release of cytochrome c. Out of four, three peptides interacted with membrane receptor PHO36 altering its structure and function and leading to a higher accumulation of O₂- and H2O2. C. neoformans cells treated with SP presented a reduction in the activity of antioxidant enzymes, corroborating ROS accumulation. However, in the presence of the antioxidant ascorbic acid, some peptides could not induce this oxidative stress and have the activity against C. neoformans affected. Curiously, two of these SPs still maintained the activity against C. neoformans and even induced the membrane pore formation as revealed by propidium iodide uptake assay, revealing their mechanism of action is ROS-independent. Additionally, SPs inhibited the biosynthesis of ergosterol, which corroborates the pore formation on the membrane of C. neoformans cells, inhibited the lactate dehydrogenase activity affecting the cell metabolism, and induced the release of Cyt c from the mitochondria inducing death by apoptosis in the cryptococcal cells. Our findings strongly suggest that SPs act by multiple mechanisms, making it difficult for C. neoformans to acquire resistance highlighting the potential of SPs as alternative molecules in treating infections caused by C. neoformans.
Klein-Gordon, Dirac and Schrodinger Equations, Matter and Wave Function Collapses, Photon Momenta and the Gamma Ray Burst based on the 4-D Euclidean Space
Authors: Hwang Jae-Kwang
Published: December 2022

The negative energy solutions of the Klein-Gordon and Dirac equations have been used to define the antiparticle with the positive energy from the Feynman - Stueckelberg interpretation in the standard model based on the 4-D Minkowski space with the relative time. The negative energy solutions of the Klein-Gordon and Dirac equations are used to define the antiparticles with the negative energy in the present 3-D quantized space model. Note that all the present results are based on the 4-D Euclidean space with the absolute time (t) and relative time (tl). Then the particle with the positive energy and antiparticle with the negative energy have the 4-D P4 = TCP = TcP symmetry. The continuity equations are derived from the Klein-Gordon, Dirac and Schrodinger equations. The Klein-Gordon and Schrodinger equations with the potential barriers are solved. The Klein paradox is explained by using the pair production of the electron with the positive energy and positron with the negative energy under the P4 = TcP symmetry, The effective velocity ( c_eff=√2 " c " ) and effective energy ("Etl =" √2 E ) along the relative time axis (ctl) give the relative time momentum of "ptl"=E_tl/c_eff =(√2 E)/(√2 c)=E/c=p_t=p_x. This indicates that the photons with the energy of E have the constant photon velocity of c and the constant photon momentum of "ptl"=E_tl/c_eff =(√2 E)/(√2 c)=E/c=p_t=p_x. For the negative energy particles, the space momentum directions are opposite to the particle velocity directions because the energy is negative. And the matter collapse to the photons at the very high particle velocity is discussed from the length expansion. It is, for the first time, proposed that the gamma ray burst is originated from the matter collapse to the photons near the black hole. Also, the wave function collapse is explained from the length expansion. The wave function collapse takes place when the measurement makes the particle velocity to be zero. It is concluded that the negative energy solutions of the Klein-Gordon and Dirac equations support the existence of the partner antimatter universe with the negative energy and negative time direction. Our matter universe has the positive energy and the positive time direction.
Cooking PaPa: An Online Application that Helps Remove the Barrier Between Modern Generation and Cooking
Authors: Khan Mohd Tauheed , Nguyen Vuong , Truong Tuan , Hoang Trang , Nguyen Tuan
Published: December 2022

During the pandemic, home-cooked meals have received more attention as people get more time for themselves and their families. It cannot deny that people have more time to prepare meals, and it is safer to cook at home since they can avoid direct contact with people who can potentially F0 or F1. For that particular reason, the number of home cooking has increased rapidly. In the article, the author pointed out that in comparison to the previous time, 42.0 percent of respondents said they cooked more frequently during the lockdown, while just 7.0 percent said they cooked less frequently. The increase in cooking frequency had a more significant impact on women than on men (p<0.05). Those who said they cooked more regularly spent more time preparing meals (78\%) and trying new recipes (73.6\%), as well as spending more time baking (67.1 percent ). In particular, the consumption of “comfort” foods (salty snacks, sweets) showed a significant rise, ranging from (23\%) to (60\%) of respondents who declared snacking more studied.Moreover, articles pointed out that in conjunction with the dramatic reduction in energy expenditure due to the impossibility of going out, this situation could have led to energy imbalance and, thus, weight gain. Noticing the massive rise in home cooking, the search for new recipes, and the need for balance meals, the idea for a cooking app called "Cooking Papa" has been proposed. As far as the research goes, the concept of "cooking" seems close but yet not easy to define. The Oxford English Dictionary defines cooking as “to prepare food by the action of heat. However, limited evidence suggests that people interpret the meaning of cooking quite differently. Moreover, the terms ‘homemade’, ‘convenience,’ ‘proper cooking,’ ‘cook,’ ‘basic ingredients,’ and ‘ready prepared’ are not uniformly understood.
Congruences involving the binomial coefficient and some applications
Authors: Tahmi Nabil , Elkhiri Laid , Derbal Abdallah
Published: December 2022

In this paper, we gave some new identities and super-congruences involving binomial coefficient, and some interesting congruences related to Fibonacci and Lucas sequence.
Ecological niche modeling in a whip spider, Heterophrynus boterorum (Phrynidae), from the Colombian Central Andes
Authors: Vásquez-Palacios Sebastian , Chirivi Joya Daniel Andrés
Published: December 2022

The species Heterophrynus boterorum is endemic to Colombia, and was described in 2013 with just a few specimens. It has morphological variation that may be correlated with environmental conditions, or with isolation processes. We modeled the potential distribution of this species using software Maxent in order to know of other possible occurrence localities and the influence of environmental variables which can condition its presence. Additionally, we contrasted the potential distribution with the National System of Protected Areas of Colombia. The species has a potential distribution in the central region of the Andes in the Cordillera Central and Occidental, which connects all known populations. Precipitation and temperature, especially during the driest season, were the most influential variables in the model, which is coherent regarding the requirements for humidity and climatic stability in Amblypygi. Only one of the known populations is recorded in a protected area, so it is necessary to design better conservation strategies to preserve H. boterorum.
Chinches semiacuáticas (Hemiptera: Heteroptera: Gerromorpha) del Parque Nacional Natural Utría (Chocó, Colombia)
Authors: Martínez Dueñas David Camilo , Morales castaño Irina Tatiana , Galindo Malagón Ximena Alejandra
Published: December 2022

Esta investigación registra las especies de chinches semiacuáticas (Hemiptera: Gerromorpha) de la franja costera del Parque Nacional Natural Utría (Chocó, Colombia). Durante una salida de campo en el mes de febrero de 2019, se recolectaron individuos en diferentes tipos de hábitats: ensenada, manglar, playa y quebrada. En cada hábitat se hicieron recolectas por medio de redes entomológicas acuáticas, con un esfuerzo de muestreo de dos horas/hombre. Se lograron recolectar 192 individuos, donde el 93% fue determinado a especie y el 7% a género. Así, se lograron registrar 11 especies y dos morfoespecies, cuatro especies para la familia Gerridae y siete para la familia Veliidae. Las morfoespecies pertenecen a los géneros Rhagovelia y Microvelia (Veliidae). Se resalta el registro de cuatro especies endémicas para el Chocó biogeográfico que han sido descritas recientemente: Rhagovelia molanoi, Rhagovelia nuqui, Rhagovelia utria y Stridulivelia chocoana. Los resultados de este proyecto estuvieron dentro del Marco de la revisión taxonómica de la familia Hydrometridae para Colombia
Primer registro del género Metadinophysis Nie y Wang (Dinophyceae: Dinophysiales) en áreas costeras del Pacifico colombiano
Authors: Hoyos Acuña Jesús Javier , Quintana Manotas Humberto Luis , Bermúdez Rivas Christian , Castrillón Valencia Fredy Albeiro
Published: December 2022

Se registra por primera vez el género de dinoflagelado Metadinophysis (Dinophyceae: Dinophysales) en la bahía de Buenaventura y el Parque Nacional Natural Uramba- PNN Uramba en Bahía Málaga del Pacífico colombiano central, se analiza su densidad con los cambios de marea. Se registraron células con contorno subtriangular y reniforme en vista ventral, epiteca pequeña. Aleta sulcal izquierda con tres costillas y la derecha muy reducida o ausente, presentando tamaño promedio 43.1 m de longitud total y 25.0 m de ancho total, la densidad del género se analizó bajo cuatro factores, la marea alta y la marea baja en la bahía de Buenaventura y en la bahía de Málaga. Se encontraron diferencias significativas entre la densidad en la marea alta y la marea baja para la bahía de Buenaventura, la diferencia entre la marea alta de la bahía de Málaga y la marea baja de la bahía de Buenaventura. Asimismo, se estableció que la distribución de la densidad no tiene ninguna estructura espacial en ninguno de los eventos mareales. Con el presente estudio se registra por primera vez el género de Metadinophysis en el pacífico colombiano, ampliando su distribución a nivel global.
Wandering Gazes on the Screen: The American Material Environment in James Benning’s Films
Authors: Horányi Péter
Published: December 2022

The experimental filmmaker James Benning has a unique way of approaching American life through a radical film language. My paper addresses the question of how American material culture and design appear in Benning’s early work. A recurring feature is his preference for the depiction of landscapes, buildings, objects, and vehicles over human characters that support viewer identification in mainstream documentaries. In the first half of the paper, I present the main stylistic features of Benning’s body of work within the context of structural film and documentary filmmaking. Then I provide a detailed analysis of three of his early films: 11 × 14 (1977), American Dreams: Lost and Found (1984) and Landscape Suicide (1986). I show how Benning was able to create a film language with structural experimentations, long takes, and wide shots that offers a perceptual experience that goes against mainstream narrative film and documentary traditions. Overall, the aim of this study is to present how Benning’s art provides an epistemological insight into American design and material culture of the 1970s and 1980s.
Space On and Off Screen: The Détournement of Documentary into Video Installation
Authors: Nogueira Patrícia
Published: December 2022

This essay proposes the détournement of the documentary film Displacement (Nogueira 2021) into a video installation, as a process to subvert the sequential documentary account of reality, as well as to interrogate space and movement on and off screen. Instead of editing and presenting the images and sounds in a continuous f low, the setup of the installation fragments the narrative and replaces the sequential format by a projected, sculptural, four-channel experience, composed of a prologue and three acts: (1) the family’s daily activities; (2) disruption of the quotidian routines; (3) the family’s displacement. While the installation projects the prologue onto clear white translucent plastic (like the ones used to cover construction sites) at the entrance to the darkroom, the three acts are projected on the three walls surrounding the audience in the darkroom. The result is an intersection of images and sounds: a juxtaposition and intertextuality of the content to offer an immersive view into family life. It also raises the question of embodiment in video installations, especially the notions of spectatorship, authorship, reality, performance, and, most importantly, what the boundaries of the screen are in the expanded practice of documentary film.
Charge-Sensitive Technique for Deformation Processes’ Study
Authors: Pantsialeyeu K. U. , Mikitsevich U. A. , Svistun A. I. , Vorobey R. I. , Gusev O. K. , Zharin A. L.
Published: December 2022

Surface charge can be used as an information parameter about the change in the state of the material under the action of mechanical stresses. The aim of the work was to develop methods for studying deformation processes in metallic and polymeric materials using a charge-sensitive method.

Experimental studies of deformation processes under tensile, compressive and impact loads were carried out on samples of various materials: aluminum alloy of AMg2 grade, steel of grade 08PS, high-pressure polyethylene of grade 12203-250 and samples of composite materials based on it, F4 polytetrafluoroethylene. As a research method, the analysis of changes in the relative values of the surface electron work function in the case of metals and the surface electrostatic potential in the case of polymers and composite materials is used. A scanning modification of a charge-sensitive probe is used as a measuring instrument.

The results of experimental studies of materials in a stress-strain state demonstrate the high efficiency of the proposed method. The research methodology makes it possible to detect local changes in the surface potential of the material in the area of deformations, which are not detected on a macroscopic scale using standard methods. The results obtained can serve as a basis for the development of new methods and techniques for studying the mechanical properties of both metals and dielectric materials.
Desarrollo didáctico de la asignatura de Biogeografía dentro del Grado de Geografía y Ordenación del Territorio de la Universidad del País Vasco/Euskal Herriko Unibertsitatea
Authors: Díaz Sanz Mª Cristina , Lozano Valencia Pedro José
Published: December 2022

Los contenidos biogeográficos, al igual que los de otras disciplinas troncales dentro de la Geografía, se configuran como esenciales y generales para todos los grados de Geografía de España. Sin embargo, se ha adolecido de un corpus general o consensuado entre todos aquellos docentes e investigadores que, de una manera u otra trabajan y desarrollan labores pedagógicas relacionadas con la materia. Este artículo pretende poner negro sobre blanco aquellas competencias, objetivos, modalidades docentes/discentes, temáticas y bibliografía que deberían incorporarse y tenerse en cuenta en el desarrollo de la asignatura a partir de un estudio de caso. Basados en la empiría de más de 12 años de impartición de esta y de todas las novedades y tendencias que a nivel de investigación y aplicación a la ordenación del territorio se están dando, se desarrolla un plan integral que, por lo menos en el País Vasco está dando lugar a buenos resultados y a una satisfacción del alumnado relativamente alta.
El aprendizaje del espacio en didáctica de la Geografía: recursos tecnológicos y TPACK para adquirir la competencia espacial
Authors: Gómez Trigueros Isabel María , Yáñez de Aldecoa Cristina
Published: December 2022

Los currículos escolares señalan como pieza clave en la enseñanza de la Geografía, el desarrollo y adquisición de la Competencia Espacial (CE). Junto a ella, la actual Sociedad de la Información y la Comunicación advierte de la necesidad de formar en Competencias Digitales (CD), de manera que se logre alcanzar una ciudadanía responsable y capaz del siglo XXI. El objetivo de esta investigación es analizar las posibilidades didácticas que ofrece la Tecnología de la Información Geográfica Google EarthTM para desarrollar diferentes conceptos y procedimientos geográficos en el alumnado y en el profesorado en formación. La metodología implementada es mixta,y el modelo de enseñanza y aprendizaje utilizado es el Technological Pedagogical Content Knowledge (TPACK). Se analizan los dos instrumentos utilizados: las propuestas didácticas diseñadas y las respuestas a un cuestionario de escala Likert, a lo largo de dos cursos académicos. Algunos de los resultados evidencian que los participantes carecen de tanto de conocimientos relacionados con el paisaje geográfico como de CE, así como una deficiente formación en CD para llevar a cabo la tarea docente.
A federated learning approach to data sharing in a food supply chain
Authors: Gavai Anand , Bouzembrak Yamine , Mu Wenjuan , Martin Frank , Kaliyaperumal Rajaram , Soest Johan van , Choudhury Ananya , Heringa Jaap , Dekker Andre , Marvin Hans
Published: December 2022

Ensuring safe and healthy food is a big challenge due to the complexity of food supply chains and their vulnerability to many internal and external factors. Recent research has shown that Artificial Intelligence (AI) based algorithms, in particularly data driven Bayesian Network (BN) models, are very suitable as a tool to predict future food safety risks and hence allowing food producers to take proper actions to avoid food safety problems to occur. Such models become even more powerful when data can be used from all actors in the supply chain (e.g., farmers, food producers, authorities) but data sharing is hampered by different interests, data security & data privacy. Federated learning (FL) may circumvent these problems as demonstrated in various areas of the life sciences mainly using linear models.
In this research, a federated BN was developed for food fraud to demonstrate the potential of FL for the whole food safety domain. This concept consisted of three geographically different data stations hosting different sets of food fraud data which have been made FAIR (e.g., Findable, Accessible, Interoperable & Reusable). It is demonstrated that a BN model can be trained on the data of different data stations while the data never leaves its data station abiding security and sensitivity requirements and that this BN model performs like the BN model trained on the complete data set pulled into one data station. We demonstrated for the first time the applicability of the federated BN in food safety and anticipate that such concept may support stakeholders in the food supply chain for better decision-making regarding food safety and food fraud control.
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3
Authors: You Abin , Yang Hu , Lai Chunping , Lei Wen , Yang Lu , Lin Jialin , Liu Shuncui , Ding Nan , Ye Feng
Published: December 2022

CMTR1, also called IFN-stimulated gene 95 kDa protein (ISG95), is elevated by viral infection in a variety of cells. However, the function of CMTR1 in colorectal cancer (CRC), especially its role in tumorigenesis and immune regulation, remains unclear. Here, we first identified CMTR1 as a novel oncogene in colorectal cancer. Based on The Cancer Genome Atlas (TCGA) database exploration and human tissue microarray (TMA) analysis, we found that CMTR1 expression was markedly higher in colorectal cancer tissues compared to that in adjacent normal tissues. High CMTR1 was correlated with poor prognosis of colorectal cancer patients. Knockdown (KD) of CMTR1 significantly suppressed cell proliferation and tumorigenicity both in vitro and in vivo, whereas overexpression of CMTR1 exhibited the opposite effects. KEGG analysis revealed that the JAK/STAT signaling pathway was differentially enriched in colorectal cancer cells with CMTR1 KD. Mechanistically, repression of CMTR1 inhibited RNAPII recruitment to the transcription start site (TSS) and repression of STAT3 expression and activation. Furthermore, PD1 blockade immunotherapy was prominently enhanced with CMTR1 KD by increased infiltration of CD8+ T cells into tumor microenvironment. Overall, it appears that CMTR1 plays a key role in regulating tumor cell proliferation and antitumor immunity.
Pathogenic lymphangiogenesis promotes autoimmune valvular carditis
Authors: Osinski Victoria , Yellamilli Amritha , Firulyova Maria , Auger Jennifer , Meier Lee , Faragher Jessica , Marath Aubyn , Voeller Rochus , Zaitsev Konstantin , Binstadt Bryce
Published: December 2022

Rheumatic heart disease (RHD) is a major cause of valvular heart disease in developing nations. Endothelial cells (ECs) are considered crucial contributors to RHD, but greater insight into contributing mechanisms is needed. Cdh5-driven EC lineage tracing in the K/B.g7 mouse model of autoimmune valvular carditis revealed new capillary lymphatic vessels that develop from valve surface endothelial cells during the progression of disease. Human rheumatic valves contained similar lymphatics. Unsupervised clustering of mitral valve single-cell RNA sequencing data revealed lymphatic valve ECs (VECs) that express a transcriptional profile distinct from other VEC populations and upregulate genes controlling extracellular matrix composition and fibrosis during disease progression. Finally, inhibiting VEGFR3 prevented expansion of this mitral valve lymphatic network and decreased valve thickening and collagen density. These studies reveal a novel form of postnatal pathogenic lymphangiogenesis that promotes autoimmune valvular carditis.
Aligning Asset Pricing Models and Neural Networks for Predicting Portfolio Returns in Frontier Markets
Authors: Jan Muhammad Naveed , Tahir Muhamma , Shariq Muhammad , Asif Muhammad
Published: December 2022

Forecasting Portfolio returns is a challenging task, and conventional forecasting models have partially succeeded in dealing with the nonlinear and complex nature of Equity Markets. Artificial neural networks are a mathematical modelling approach that are resilient enough to forecast portfolio returns in volatile and nonvolatile markets and act like the human brain to simulate the behaviour of stock prices. This research documents the predictive ability of Artificial Neural Networks (ANN) by using the constructs of Fama and French three-factor and five-factor models. A comprehensive methodology of neural networks is applied to achieve the purpose of forecasting. The methodology includes the declaration of the three layers, the hidden layer neurons for processing, and varying parameters for an effective ANN system. The study employs 48-month rolling windows to calculate and compare forecasting errors among competing asset pricing models. The predictive performance of ANN is measured by mean squared, and the accuracy of ANNs under both the pricing models and the accuracy level is evaluated by the Diebold Mariano test. The significant findings of the study include the identification of the optimum architecture of the ANN under both asset pricing models, the nonappearance of the overfitting phenomenon of the networks, and the investor’s compensation for holding high-risk portfolios.JEL Classification:C45, D53, E37, G11, G17
A geometrical approach to g-digroups
Authors: Gaviria Isaías David Marín , Rodríguez-Nieto José Gregorio , Salazar-Díaz Olga Patricia , Velásquez Raúl
Published: December 2022

Representation group theory plays an important role in group theory, much more in geometry, on which we can determine, in many cases, what kind of geometry or geometries a manifold M supports by knowing a faithful representation of the fundamental group Π1(M) in the group Iso + (M) of preserving-orientations isometries of M. Motivated by this and by the definition of a g-digroup action given in [1], in this paper we present a study of such action by proving some interesting results that are well known in group actions, for example: the orbit stabilizer theorem, the class equation, Burnside’s formula and we relate g-digroup actions with trioids. We introduce the definition of representation of a g-digroup into dialge-bras and a strong connection with g-digroup action, like in the case of group. We present the g-digroups as an invariant of quotient orbifolds.
Structure optimization of guide vane on combustion performance of premixed H 2 /air in micro cavity-combustor
Authors: Kim Insong , Yu Qingbo , Pak Unsong , Thae Wonhyok , Yu Kisong
Published: December 2022

The application of the cavity-combustor in the micro-combustion is one proposal to stabilize the flame and improve the combustion performance. The structure of the guide vane is an important factor of enhancing the effectiveness of the cavity, which is a key part of the cavity-combustor. Based on previous studies on the micro cavity-combustor with guide vanes, numerical analysis was performed on the effects of the shape of the guide vane on the combustion characteristics of the premixed H2/air. The investigation and comparison were conducted for the micro cavity-combustor with slash-shape guide vanes (CCSG) and L-shape guide vanes (CCLG) under different inlet velocities (6–24 m/s) and equivalence ratios (0.6–1.5). The analysis results show that CCSG has better flame stability and combustion performance compared to CCLG. A multi-objective optimization method for the guide vane structure of the combustor was proposed and the optimum parameters were obtained by applying it to the CCSG. The length of the guide vane (L3) and the vertical distance between the guide vane and the wall (S) were used as parameters, and the problem of minimizing the combustion efficiency and total pressure loss in the combustor was set. The relationship between the structural parameters of the guide vanes and the combustion performance in the combustor was modeled using the BP (back propagation) neural network. The validation of optimization was verified through comparative analysis of the original structure (L3 = 0.5 mm, S = 0.15 mm) and the optimum structure (L3 = 0.5324 mm, S = 0.3834 mm).