bluuebunny/crossref_metadata_2025 huggingface dataset:
Virtual Reality as Treatment Method for Knee Osteoarthritis - Short Review
Authors: Vrushali Dod  , Pratik Phansopkar
Published: November 2022

Virtual reality is computer-generated technology for therapeutic uses and rapidly growing in popularity. This review focused on the outcomes of the study show that virtual reality as treatment approach is a safe and acceptable therapy providing participants with satisfaction and motivation to exercise. Therapists are using VR to help people rehabilitate from osteoarthritis, strokes and injuries. The efficiency of Virtual Reality treatment was observed in patient with OA knee and many other diseases. Virtual reality approach Physical rehabilitation focuses on pain treatment, gait re-education, body balance improvement, increased mobility, and muscular strength development. Because of VR and modern technology, this activity should be done quickly and safely under the supervision of the therapist. Virtual reality is cost-effective of VR headsets and the expansion of Virtual reality apps. Using virtual reality to create fascinating and demanding settings can help you active and interested in your rehab.
Robotics in Lower limb Amputate to improve functional activity
Authors: Amisha Prakash Zade  , Priyanka Telang
Published: November 2022

Phantom limb pain (PLP) is defined as pain experienced by a bodily part that is no longer existent. Stump pain is pain felt in the severed limb's remaining component, whereas phantom sensations are nonpainful sensations felt in a bodily part that no longer exists. People with bilateral limb amputation did not have a higher rate of phantom pain or feeling than those with single limb amputation. There has been a link discovered between the PLP and residual limb pain. Preamputation pain has also been linked to an increased likelihood of getting PLP.
Matrix Rhythm Therapy For Shoulder Joint and Leprosy – A Review Article
Authors: Taj Afreen Sheikh  , Priyanka Telang
Published: November 2022

The Matrix Rhythm concept is founded on the premise that all cellular actions, whether preventive, therapeutic, regenerative, or destructive, operate largely through the cell's environment. The frequency of pulsation in muscle cells is 8-12 Hertz. Outside of the 8-12 Hertz range, muscle pulsation frequency is linked to aches, muscle tension, and other health issues. Variations in pulse frequency and the logistics of the life process at the cellular level are linked to changes in muscle flexibility and plasticity. Specific vibrations in skeletal muscles and the nervous system are activated and rebalanced by the MRT. The MRT generates an oscillating rhythm that increases lymphatic venous perfusion of the extracellular space, in which the anti-edematous benefits occur. We reviewed the Matrix Rhythm Therapy procedures in treating various pathological disorders in this research.Matrix rhythm therapy is useful in treating complaints such as enhancing Range of motion, increase in muscle strength and lowering in pain, according to the result of this research. In terms of physical health, functional outcomes, and satisfaction, matrix rhythm therapy delivers long- term benefits for those with frozen shoulder and leprosy.
Robotic devices and systems in physiotherapy- A review
Authors: Rajas Mudey  , Vishnu Vardhan
Published: November 2022

Robotics is a term which is used for the combination of multiple terms such as engineering, technology, rehab etc. Even, the term artificial intelligence has proved to be useful in taking robotics ahead. Walking ability is linked to a variety of daily duties, whilst immobility can considerably reduce the standard of living of those suffering from locomotory illnesses. Researchers from all over the world are working to enhance or develop medicines and gadgets that may aid those individuals.By assisting therapists in delivering ongoing instruction over a long period of time and gathering data to monitor improvement robotics-assisted rehabilitation technology has the potential to improve the efficacy and availability of therapy.This review research summarizes the effort that has gone into the implementation and evolution of robotic systems for rehabilitation.Home-based rehabilitation devices, which make use of readily available state-of-the-art technology, are offered as a long-term solution to the current situation.In order to effectively enroll in this therapy for research reasons, efforts are made to discover the appropriate form of treatment, the amount and quantity of training technique, and the patient's features. Robotic therapy should be considered as a therapeutic tool that may be utilized to provide a more complex, controlled multimodal stimulation to the patient, as well as to affect the development of neural pathways through movement. In order to effectively enroll in this therapy for research reasons, efforts are made to discover the appropriate treatment, the length and quantity of training technique, and the patient's features.
Advancement of biomolecular engineering in Parkinson disease
Authors: Vaishnavi Wagh  , Ragini Dadgal
Published: November 2022

Parkinson's Condition (PD) is the second most common degenerative neurological disease, affecting 10 million people globally. Nigrostriatal degeneration is linked to decreased motor and non-motor functioning in this chronic illness. Resting tremor, stiffness, akinesia (or bradykinesia), and postural instability are the four cardinal symptoms of Parkinson's disease. Because the symptoms of Parkinson's disease are similar to those of other age-related disorders like SWEDD (scans without evidence of dopaminergic deficit), essential tremors, and Parkinson's disease, early diagnosis is difficult. A synucleinopathy is Parkinson's disease (PD) with Lewy Bodies (DLB).Although both genetic and environmental variables are assumed to play a role in Parkinson's disease (PD), there was no direct evidence to support either as a causal component until recently. Six distinct genes have been discovered as producing familial PD in the last eight years. They back up the idea that similar pathogenetic pathways exist across the spectrum of Parkinson's disease etiologies. Mutations in α-synuclein, parkin, UCHL1, DJ1, PINK1, and LRRK2 cause.Parkinson's disease, which is inherited in a Mendelian form. Overexpression of α- synuclein and parkin causes mitochondrial issues, but DJ1 and PINK1 are mitochondrial proteins. These same proteins regulate proteasomal function and play a role in the oxidative stress response.Doped carbon nanotubes, especially phosphorus-doped carbon nanotubes, can efficiently prevent the formation of α- synuclein amyloid, suggesting that they could be utilized to treat Parkinson's disease. More in vitro and clinical research is, however, necessary. As previously stated, αsynuclein could be a therapeutic target for Parkinson's disease and other synucleinopathies. The most promising option would be small chemicals that may modify the structure of protofibrillar forms of α-synuclein and render them nonpathogenic. Given the pathogenic consequences of αsynuclein's feed-forward amplification loops, a range of therapeutic options will almost certainly be required.
Development and validated spectrophotometric method for the determination of Ceftriaxone in pharmaceutical preparations
Authors: Mohammed Khalid Qahtan  , AN Alshirifi
Published: November 2022

The study involves the development of a simple, rapid, selective, and low-cost spectrophotometric method for the determination of ceftriaxone as pure and in its pharmaceutical preparations. The ceftriaxone (CF) was diazotized by sodium nitrite NaNO2 solution in the presence of hydrochloride acid HCl in the ice bath at range of 0 to 5 ºC to form diazonium salt, and then coupled with 4,5-diphenylimidazole reagent (4,5-DPI) in a basic solution of sodium hydroxide solution to form a purple color water–soluble azo dye as a result, that has a maximum absorption λmax at 550 nm opposite reagent blank, in the optimum conditions. The linearity of the process obeyed Beers law in the concentration range of 10 to 100 μg/mL at a correlation coefficient R2 of 0.9973. The molar absorptivity was 3772.08 L/mol.cm. The detection limit and quantification limits were 4.9425 and 16.475 μg/mL, respectively. Relative error and precision were determined to be 2.8% and 1.44%, respectively. The resulting stoichiometry of the AZO dye (drug: reagent) formed was found 1:1.
Association between SNPs(rs1058587 and rs1054564) in GDF15 Gene and Development of Prostate Diseases
Authors: Anwar Hameed Darwish  , Rawaa AlChalabi  , Faisal Harith
Published: November 2022

The prostate is a gland that covers the necks of the bladder in men and aids in ejaculation during sexual activity as well as the storage of some seminal fluid. The three most prevalent conditions affecting prostates are inflammation, benign enlargement, and prostate cancer.180 participants were enlisted to detect two SNPs (rs1058587 and rs1054564) by using the tetra-arm approach in the promoter of the GDF15 gene, then estimate the serum level of GDF15 protein by sandwich ELISA to investigate its relationship with disease severity. Variation of frequency distributions of genotypes and alleles among groups showed a positive association with the serum level of GDF15 protein as a relative risk factor. The study reflects a relationship between the variation in the expression of the two SNPs in the promoter and the serum level of protein, thus it can be considered as an indicator to measure the progression of prostates disease.
The effect serum iron, vitamin B12 and ferritin levels in adult patients infected with Helicobacter pylori
Authors: Nesreen Ahmed Nasser  , Zainab Sadeq Yuosif  , Rana Warid Maya
Published: November 2022

Objective : This study aimed to investigate the relationship between hematological parameters, serum iron, and vitamin B12 levels in adult hospitalized Palestinian patients infected with Helicobacter pylori.Methods : The collected the data, prospectively, all H.Pylori cases admitted in lab private during the study period between April 2022 and August 2022. During the five months , (30) cases with H.pylori and (30) control . patients had H.pylori positive. laboratory analysis of inflammatory indices and organ function was accomplished for the sum total of cases and controlsRESULT : The results in this research showed that there is a highly significant between stomach germs(H. pylori), iron, ferritin and vitamin B12, and there is non-significant with vitamin D.
Evaluation of dental implants failure rate in medically compromised patients: A randomized case control study
Authors: Santosh Kumar S Mathpati  , Vijayalaxmi M Halli  , Anshu Gupta  , Madhvika Patidar  , Prerna Raje Batham  , Jeethu John Jerry
Published: November 2022

Aim: The present research was done to evaluate dental implant failure in medically compromised patients compared to control group.Materials and Method: This randomized control study comprised of 50 medically compromised patients of both genders who underwent dental implants 7 years ago (Group I). Equal number of healthy subjects was taken as control (Group II). Amount of bone loss around the implant over 1mm of bone loss in the first year and over 0.3 mm bone loss every subsequent year were considered as failures.Results: The most commonly seen medically compromised patients were diabetes (20) with 24 dental implants followed by Hypothyroidism (12) with 12 implants, osteoporosis (8) with 15 dental implants, organ transplant (7) with 8 dental implants and CVD (3) with 3 dental implants. There was statistically significant difference (p< 0.05). The implant failure was 15 (30%) in group I, and 3 (6%) in group II. At first year, in group I, mean bone loss around implant was 1.18 mm and 0.4 mm in group II. Up to 5 years, in group I, mean bone loss around implant was 2.8 mm and 1.3 mm in group II.Conclusion: Among medically compromised conditions, higher failure rate was found in diabetes.
BATTERY MANAGEMENT IN ELECTRICAL VEHICLES USING MACHINE LEARNING TECHNIQUES
Authors: V Sravan Kumar  , A. Yasmine Begum  , Md Moniruzzaman  , K.V.Daya Sagar  , L Malleswara Rao  , Santhosh P.
Published: November 2022

Electric vehicle (EV) manufacturers are increasing production in order to keep up with the fast growing demand from customers. To meet the ever-increasing demand for electric vehicles (EVs), both well enough and up-and-coming manufacturers of automobiles will need to immediately boost their production of EVs while simultaneously lowering their prices in order to compete. However, the production of electric vehicles comes with its own set of challenges for automotive manufacturers who are looking to survive in the years to come. By generating digital twins of both their products and their production processes, businesses have the ability to virtually develop and test complete assembly processes as well as entire facilities. This speeds up the process of transitioning to high-volume production without compromising the product's quality. Battery management is one of the most challenging components of driving electric vehicles (EV). Batteries and the amounts of energy that they can store were the focus of this research. Researchers make use of a technique that is referred to as "machine learning" in order to monitor and improve the management of electric car batteries.One of the most challenging factors in Electrical Vehicles (EV) is battery management. This research paper discussed the effective use of battery management and it's capacity. Researchers uses a Machine learning technique to monitor and improve the level of managing techniques in EV's batteries.
Comparison of the Adhesion Rate of Implant Cemented Coatings with 3 Types of Glass Ionomer Cement, Zinc Phosphate and Resin on Blinds Made of Adhesive Composite after Thermal Stress
Authors: Abbas Rezapour  , Nadieh Qaderi  , Shaghayegh Golalipour  , Seyed Masoud Sajedi  , Soheil Hariri
Published: November 2022

One of the treatment methods in the field of dental prostheses is placing veneers on severely damaged root treated teeth. The holding power of the veneer is one of the important success factors in such treatments, especially when the teeth have short crowns. One of the factors that can affect the strength of the coating on such teeth is cement. In this interventional laboratory study, silver cast alloy coatings were made on 14 identical dies made of Core Max II, and the dies were randomly divided into 3 groups of 10, and in each group, the coatings were made on the die made of Core Max II was cemented with one of zinc phosphate cement (Harward), glass ionomer (Fugi GC) and Panavia (Kurary) F. Based on quantitative analysis, there was a significant difference between three glass ionomer cements, zinc phosphate and Panavia F in terms of setting. An ideal cement should have good mechanical properties to resist functional forces, adhere well to the underlying surface of the coating, and have high stress tolerance. In addition to cement, the type of blind building material and the physical and chemical relationship between adhesive cement and blind building material are also very important.
A Novel Technique to Restore a Large Maxillary Defect- A Case Report
Authors: Surabhi Duggal  , Shailesh Jain  , Prashanti Wahengbam  , Anu Sharma  , Maitreyi Ranjan  , Sahba Hassan
Published: November 2022

The causes of maxillary defects can be congenital or acquired in nature and management of these defects often require surgical removal of a part or almost the whole of the maxilla. This may result in establishment of oro-antral communication which ultimately hampers the daily routine activities of the patients such as speaking, swallowing, sneezing and coughing. Improvement of the defects with obturator prosthesis has been found to be beneficial to the patients. However, one of the main obstacles in restoring a large defect is the heaviness of the prosthesis which makes it non-retentive. To conquer these difficulties, diverse techniques are used to build up hollow bulb obturators. Here we report a case of large maxillary defect in a 75 year old male with Class I Aramany’s defect which was restored by a provisional obturator designed in the shape of a close hollow bulb using a clear and streamlined method for fabrication.
EVALUATING THE HATCH-WAXMAN AMENDMENT’S INFLUENCE ON FDA'S GENERIC MEDICATION APPROVAL PROCESS
Authors: Subhadarshini Bhagyashree  , R Kamaraj
Published: November 2022

Generics are drugs marketed by their chemical names, not brand names or chemical compositions. Generic drugs are less expensive. The United States Food and Drug Administration (USFDA) allows generic drugs when patents expire or owners renounce their rights. Competition lowers drug prices once generics are accessible. The Food and Drug Administration monitors the drug business. The Senate confirms the Food and Drug Administration Commissioner's nomination. Food and medications are controlled less than lasers, cell phones, and condoms. The Food & Drug Administration designated 1938–1962 medications as "pioneer goods. Kefauver-Harris requires all drug firms to submit accelerated applications (Abbreviated New Drug Application). Medicaid and Medicare modifications to the Social Security Act popularised generic medications. The 1984 law accelerated the launch of generic pharmaceuticals law and boosted generic drug introduction. The 1992 Generic Medication Enforcement Act combats fraud and misuse. The 1984 law accelerated the launch of generic pharmaceuticals.
Characterization of a Polymorphism in the Stimulatory Region of the TNF Gene in Type 2 Diabetic Patients in Iraq
Authors: Huda B. Hussein  , Ahmed D. Jabbar
Published: November 2022

The current study aims to analyze the distribution of the TNF-α gene and TNF-β polymorphism (-308G/A) in type 2 diabetes mellitus (T2DM) patients. According to world health organization the prevalence of diabetes is rising exponentially. Tumor necrosis factor alpha and beta are members of the tumor necrosis factor (TNF) super-family considered as pro inflammatory cytokine which play major role in DM pathogenesis. single nucleotide polymorphism reported to have associated with type 2 DM. Frequency of TNF-a G308A polymorphism was determine in different ethnic groups and was found variable highly. Few studies recorded appositive association between DM and TNF-α polymorphism; including meta-analysis failed to find such association. Our finding revealed that the TNF-α gene polymorphism (-308G/A) had 38 (12.50%) of G/G genotype, 44 (45.83%) of G/A genotype and 40 (41.67%) A/A genotype showed in this population. This preliminary result indicated that G/A genotype was a common in the TNF-α gene polymorphism (-308G/A) in T2DM patients while healthy control group does not exhibit AA and GA genotype.
Study the X-ray attenuation for a voltage range (20-35)Kv for copper-based smart alloys by adding silver and micro-particles
Authors: Mahmood Abrahim Mahmed  , Fareed Majeed Mohammed  , Raed Najeeb Razooqi
Published: November 2022

In this paper, the attenuation coefficients of X-rays for a range of voltages (20-35) kV were studied for copper-based alloys (Cu + 0.05 AL + 0.03 Ti) according to the order (A1,A2,A3,A4,A5),by adding percentages of silver (X=1,2,3,4,5)% with two particle sizes (Nano) and (Micro) to the alloy ( Cu92-x +5%Al +3%Ti+ Ag x) according to the orders (B1,B2,B3,B4,B5) and (C1,C2,C3,C4,C5) All alloys were sintered at (9000C) for a period of (4) hours.The results showed a direct relationship between the attenuation coefficient and the compression pressure. At the operating voltage (20Kv), the linear attenuation was increased (53.6%) and the mass attenuation was (53.8%), the hardness increased by (45%) and the porosity decreased by (18%) when comparing the results of Alloy (A1). with (A5), respectively, and it was also found that the relationship is direct between the attenuation coefficient and the percentages of silver addition, as it was noticed that the linear and mass attenuation coefficients increased by (34.5%) (34%) when comparing the results of (B1) with (B5), respectively, and the increase is By (33.9%) (33.5%) when comparing the results of (C1) alloys with (C5), the hardness has increased by (33.4%) (32.2%) when comparing the average values of alloy results from (B1) to (B5) and alloys from ( C1) to (C5) and the porosity decreased by (37.6%) (31%), respectively. The attenuation coefficient is inversely proportional to the operating voltage, as it decreased by (20%) when comparing the results of voltages (20Kv) with (35Kv) for alloy (B5) and decreased by (26.4%) for alloy (C5).
A THOROUGH ANALYSIS OF THE STATE OF VIOLENCE IN CONTRADICTION OF WOMEN’S IN MAJOR DISTRICTS OF KARNATAKA
Authors: Pohane Deepali Dnyaeshwar  , Jyoti Rajpoot
Published: November 2022

When it comes to human rights violations, violence against women is a major problem. In the last two decades, violence against women has become the world's most serious scourge. Despite the government's taking all necessary steps, daily violence is increasing. Domestic violence is a global issue that cuts across cultures, religions, classes, and countries. Despite its widespread occurrence, such violence has long been perceived as an inescapable matter of legal or political concern. Because of the cultural creation of public-private divides, domestic abuse against women is hidden. Women's violence has a variety of harmful repercussions. Lower socioeconomic status, dysfunctional families, and gender inequality are all instances. It causes estrangement and separation from couples, divorce, physical health problems, and emotional and psychological health problems in women's daily lives. Education and job for women help to reduce violence against women to a larger extent. Mass awareness campaigns organized by women activists and non-governmental organizations (NGOs) are critical in reducing violence against women.
Laboratory Errors In Pathology And Troubleshooting Methods
Authors: Sandra Sagar  , Karthikeyan Ramalingam  , Pratibha Ramani
Published: November 2022

Pathologists play an important role in the final diagnosis for the patient and help the clinician in appropriate treatment planning. Both clinicians and pathologists have a crucial role in the laboratory process and it should be monitored properly for accurate and timely reporting.There are many steps in the laboratory process, where errors can occur which can affect the final diagnosis and prognosis for the patient. Errors can be major or minor but it eventually affects the patient's outcome. The laboratory process is broadly classified into three categories- pre-analytic, analytic and post-analytic phases. The errors that could frequently occur in each phase and the troubleshooting methods are broadly discussed in this article. Errors that have occurred should be investigated properly by identifying the main source of error and preventive action should be taken to avoid it in the future.
Role of Hyaluronic acid in various diseases with special emphasis on Periodontal inflammation - A review
Authors: Ahmed Elhassan  , Karthikeyan Ramalingam  , Syed Wali Peeran  , Rajendran Ganesh
Published: November 2022

Hyaluronic acid is a naturally occurring polysaccharide of extracellular matrix of connective tissues, synovial fluid, and other body tissues. It has an important role in regulating interactions intra and extracellularly between different growth factors, in addition to regulating osmotic pressure, maintaining tissue volume and lubrication.Periodontitis is an multifactorial inflammatory disease that affects teeth supporting structures which results in teeth loss. It is considered a wide world cause of teeth loss in adults. In addition to its local effect, teeth loss, it can have systemic impacts on many systemic organs. Although its main cause is bacteria, exaggerated host response and risk factors such as smoking, diabetes mellitus, HIV/AIDS, family history, and certain medications increase the disease progress.Hence teeth supporting structures are connective tissues and hyaluronic acid is a main component of connective tissues, a correlation of both in health and disease is explained in this article
A Retrospective Evaluation of Centric Relation Techniques Used in Different Edentulous Conditions for A Temporary Partial Denture Fabrication
Authors: M.Sai Teja Reddy  , L.Keerthi Sasanka  , Dhanraj Ganapathy
Published: November 2022

The aim of this study was to retrospectively evaluate the commonly used technique for recording centric relation in temporary partial denture cases among dental students. A total of 820 data entries were taken, duplicate and missing entries were omitted. So a total of 665 entries were evaluated. The data was collected from patient records in Saveetha Dental College, over a period of one year. The evaluation was based on the technique used by the dental students, to record centric relation for temporary partial denture cases. The results of the study were subjected to statistical analysis. Data analysis was done using SPSS software version 23.0.Chi-square test and frequency evaluation was done to evaluate the most frequently used method to record centric relation. It was found that about 93.08% of the dental students have used the pressure method and 6.92% of them have used the pressure less method.(P value = .001) and found to be statistically significant. The present study concluded that most of the dental students preferred the pressure method to record Centric Relation while fabricating a temporary partial denture.
Assessment Of Knowledge, Attitude and Practice Survey on Does Time Pressure Impact on Dentist Diagnosis in Complete Denture.
Authors: Neppala Gowtham  , Subhasree.R  , Dhanraj Ganapathy
Published: November 2022

Introduction: Dentistry is considered one of the hectic and stressful professions. Work-related stress has been linked to the development of mental health difficulties among dentists, including depression and a higher risk of burnout. Beginning in dental school and postgraduate training, dental professionals face a variety of stressors that might persist or worsen throughout their careers. Dealing with tough and demanding patients, running behind schedule and time demands are the most commonly mentioned stressors, followed by staff concerns and pressures from third parties.Materials and Methods: In May 2020, a cross-sectional survey was undertaken throughout dentistry colleges in southern India. It was decided to create a questionnaire with 27 questions. Through electronic media, this questionnaire is distributed to prosthodontic postgraduate students, prosthodontists, interns, general practitioners, and postgraduates from other departments. Results : In this survey, the response rate of the participants was satisfactory. Regarding the diagnosis of complete dentures, the majority of the participants had high knowledge (65%), attitude (78.30%), and practice (73.72%). A total of 155 dentists answered to the survey, which was sent out to 200 dentists. It yields a 95 percent response rate.Conclusion: Within the limitations of the investigation, this cross-sectional descriptive study found that prosthodontists had extensive knowledge and awareness of treatment planning and diagnosis of complete dentures under time constraints, but ordinary dentists have insufficient understanding.
Awareness Of Medicinal Effects of Tamarindus Indica Among Dental Students
Authors: Vatika Agarwal  , Dhanraj Ganapathy
Published: November 2022

Introduction: Tamarindus indica L also recognized as Tamarind is a common plant species in the Indian subcontinent. Tamarind derivatives are widely used in Asia, african and south american nations as medical treatments. In ancient indian medicine and african traditional medicine ,tamarind ingredients, seeds, fruits , and leaves have been commonly used.Aim : The study aimed to assess knowledge amongst dental students of the medicinal effects of Tamarindus indica.Materials and method: A cross-sectional analysis with a self-administered questionnaire was performed, with Ten questions distributed among 100 dental students. In medical applications, the questionnaire measured understanding of Tamarindus indica treatment, its anti inflammatory properties, anti-lipedemic properties, anti-pyretic activity, and its phytocompound action mechanism. We reported and evaluated the responses.Results: 21% of the respondents were aware of the medicinal applications of Tamarindus indica therapy.15% were aware of the anti inflammatory of Tamarindus indica therapy. 13% were aware of the anti lipedemic activity of Tamarindus indica therapy.10% were aware of the anti pyretic activity of Tamarindus indica therapy.8% were aware of the mechanism of action of phytocompounds of Tamarindus indica therapy.Conclusion: There is limited awareness amongst dental students about the use of Tamarindus indica therapy in medicinal applications. Increased awareness campaigns and dental education initiatives coupled with increased value for curriculum changes will further improve knowledge and understanding of Tamarindus indica therapy.
Current Trends in Bone Grafts - A Review
Authors: Harini Sri  , Dhanraj Ganapathy  , Suresh Venugopalan  , Madhura Deshmukh
Published: November 2022

Human bone is susceptible to damage from infections, fractures, and diseases. They do, however, have an amazing ability to repair themselves after being exposed to such factors, which is accomplished by a dynamic process of remodeling, maturation, differentiation, and regulated resorption. Larger defects, on the other hand, cannot be fully restored because their sizes exceed the capacity of the bones to repair. In such cases, medical intervention is required to stabilize, align, and support the damaged bone region so that lost function is restored. The goal of Bone Tissue Engineering is to incite and promote the natural healing process of bone, which does not occur in critical-sized defects. A biocompatible synthetic bone scaffold must be biodegradable to allow native tissue integration and must mimic the multidimensional hierarchical structure of native bone. Several biomaterials have been studied for their potential as bone scaffold materials, including ceramics, metals, polymers, and composites. Polymers, on the other hand, have emerged as the primary material in bone tissue engineering due to their tunable physiochemical properties, biocompatibility, and controllable biodegradability. This literature review provides insight into current trends in bone graft
Evaluation Of Immediate Bone Level Changes Around Different Implant Systems From Surgical Stage To Prosthetic Stage - A Retrospective Study
Authors: Madhura Deshmukh  , Nabeel Ahmed  , Harini Sri  , Sanjog Agarwal  , Dhanraj Ganapathy
Published: November 2022

This study evaluates the immediate bone level changes around different implant systems from placement to 3 months post - operative radiographically. The assessment of bone loss at the crestal module level of different implant systems relates the findings to the image on a radiograph. The purpose of this study was to evaluate the immediate changes to marginal bone level radiographically around different implant systems. A total of 100 implant radiographs were assessed which were placed in different areas of the jaw. It was found that thread exposure of Straumann roxolid SLActive™ surface implants was least compared to Nobel Biocare™ conical connection / Groovy and Equinox™ implant systems. Thus, radiographs serve as critical parameters to evaluate marginal bone changes surrounding dental implants.
Incorporation Of Ajwain Extract in Provisional Luting Cement for Long Term Inhibition of Bacterial Infiltration
Authors: Madhura Deshmukh  , Subhabrata Maiti  , Rajeshkumar S  , Dhanraj Ganapathy
Published: November 2022

Aim: The focus of this study was to evaluate the antimicrobial properties of Ajwain seeds when incorporated in provisional luting cement.Materials and Methods: A total of 12 samples of provisional cement [TEMP-BOND™] were prepared. Extraction from 5gms weighed Ajwain seeds with 100ml distilled water was done until reduced to 10ml. Minimum Inhibitory Concentration(MIC) was determined using agar diffusion broth method against Streptococcus Mutans and Candida Albicans. Independent t test was conducted to assess the level of significance of difference between mean values. Results: For both Streptococcus Mutans and Candida Albicans , the difference between two methods (Incorporated or Dipped/Coated) showed statistically significant difference (p<0.05) in antimicrobial activity and both the methods are clinically acceptable as it had adequate zone of inhibition.Conclusion: The zones of inhibition in the agar diffusion test showed the antibacterial efficiency of provisional luting cement when incorporated or dipped with ajwain extract is more than the control group and Ajwain can be considered as a promising natural source of antibacterial agent for management of dental secondary caries.
Removable partial denture - Accuracy in digital workflow
Authors: Vatika Agarwal  , Dhanraj Ganapathy  , Subhabrata Maiti  , Sanjog Agarwal
Published: November 2022

This study aimed to compare the fit and accuracy of metal frameworks for removable partial dentures (RPDs) made with conventional and digital fabrication techniques. On a representative model, maxillary RPD metal frameworks (N=5, n=2 each group) were created. A conventional casting of milled RPD patterns (C-M), and a conventional casting of printed RPD patterns (C-P), were all used to create RPDs. By creating replicas with silicone registration material and measuring under a digital microscope, the fit accuracy of RPD frameworks was examined.For the accuracy measurements (m), a total of 11 sites and 29 areas in the RPD metal frameworks were taken into account. Wilcoxon signed rank and the Friedman test were used in the statistical analysis of the data (p 0.05). Prior to finishing and polishing, the fit accuracy of the C-M approach (118 m) was significantly superior (P .001) when compared to other techniques. After finishing and polishing, the C-M approach demonstrated comparable fit accuracy to the C-P. When RPD precision is taken into account, it was observed that digital techniques were efficient and clinically acceptable.
Assessment of Ultrasonography Diagnostic Capacity in Women with Stress Urinary Incontinence with or without Pelvic Prolapse
Authors: Tayebe Jahed Bozorgan  , Elham Keshavarz  , Hoda Etemad Zadeh  , Zahra Salehi
Published: November 2022

Aim: The aim of this study was to assess the diagnostic validity of Ultrasonography in women with Stress Urinary Incontinence (SUI) with or without pelvic prolapse.Method: In this cross-sectional study, women with SUI were enrolled. The first group consisted of 25 patients with vaginal anterior wall prolapse, and the other group included 18 patients without vaginal anterior wall prolapse. After Systemic and genital examinations, the patients underwent the coughing test and Valsalva maneuver. The urinary leakage was examined during coughing. All the patients with positive coughing test underwent transprineal ultrasound. The posterior uretherovesical angle (β angel) as well as the bladder neck funneling were evaluated and recorded at both resting and during Valsalva.Results: In the patients with prolapse, the mean values of β angel were 121.0±25.9 and 137.7±24.5 degrees at the rest and during the Valsalva respectively. In the patients without prolapse, the means of β angel were 124.2 and 142.5 degrees at the rest and during the Valsalva respectively. The sensitivity and specificity of β angel were higher in patients with prolapse. During the Valsalva, β angel >120° and Bladder neck funneling showed higher PPV and NPV in the patients with prolapse than patients without prolapse. At the rest; however, β angel >120° delivered higher PPV and NPV in the patients without prolapse group. At the rest, β angel > 114° rendered the sensitivity and specificity of 80% and 55% respectively. During the Valsalva, β angel >129° revealed the sensitivity and specificity of 80% and 45% respectively.Conclusion: It seems that ultrasound is not appropriate enough to be an alternative diagnostic tool for urodynamic test in detecting SUI.
To Evaluate The Efficacy Of Bioresorbable Seprafilm Membrane In Avoiding Abdominal Adhesions
Authors: Dr.Disha Joshi, Dr.V.V.Kanase, Dr Nimesh Srivastava
Published: November 2022

Aim: To evaluate the efficacy of bioresorbable Seprafilm membrane in avoiding abdominal adhesions.

Material and methods: After obtaining approval from the appropriate institutional review board, this research was conducted within the department of General Surgery. Patients who needed a Hartmann procedure for diverticulitis or rectosigmoid blockage were randomly assigned to receive Seprafilm or to act as a control patient.

Results: This research covered 100 patients in total. 50 patients were randomly assigned to receive Seprafilm while the other 50 served as controls. There were no significant variations in medical history or preoperative physical examination. At the midline incision, five patients got three Seprafilm membranes, 35 patients received two membranes, and ten patients received one membrane. In 40 patients, additional surgical operations were performed during the Hartmann procedure. In the Seprafilm group, 8 patients had appendectomy, 6 had surgical decompression of the small intestine, 3 had his peritoneal dialysis catheter removed, and 3 had ovarian cyst resection and partial small intestinal resection for unintentional bowel perforation. In the control group, 8 patients had further appendectomy, 6 patients had splenectomy, 3 patients had suturing for an iatrogenic bladder damage, and 3 patients had partial small bowel resection for a mesentery abscess. The median blood loss in the Seprafilm group was 352mL and 420mL in the control group. Postoperative wound healing was abnormal in 18 of the Seprafilm patients and 14 of the control patients. The time between the original operation and the follow-up surgery was not statistically different across groups. The median interval in the Seprafilm group was 6 months (range 2-17) and 4 months in the control group (range 1–31).

Conclusion: we concluded a decrease in the degree of adhesion development following the application of Seprafilm in Hartmann procedure patients compared to controls.
MUCOROMYCOSIS: A DOUBLE BLOW TO THE COUNTRY AMIDST THE COVID 19 PANDEMIC
Authors: Dr. Ashok Kumar, Dr. Shivani Bansal , Dr. Urvashi Khan
Published: November 2022

INTRODUCTION:

American pathologist R.D. Baker coined the term mucormycosis. Fungal infections are on a rise in the past 2 decades. It is defined as an insidious, broad aseptate ubiquitous fungal infection caused by members of mucorales and zygomcotic species.(1) It is colloquially termed as black fungus, when viewed through microscope it shows dark spherical spores and so the name. Earlier it was also known as zygomycetes, which means primitive fungi with broad, asepta including mucor, rhizopus, absidia and cunninghaemella. It is an opportunistic infection which is widely distributed in nature and predominantly in soil and thrives in dead and decaying substrates. It affects various organs involving the blood vessels causing thrombosis, infarction and necrosis of tissues and organs.  As of 26th May 2021, India had noted approximately 12000 cases of mucor along with the Second wave of COVID 19, due to its fatality; it has become a notifiable disease under epidemic act.(2)
A case Report On ichthyosis Vulgaris
Authors: Rajesh D. Bhoyar  , Sarika Khadse  , Pratiksha Munjewar  , Roshan Umate
Published: November 2022

Introduction: Ichthyosis is a rare skin condition that primarily affects the trunk or extremities, omitting the flexural areas of the body, and is characterized by dry, fish-like scales (Dahl, 2019). There are around 20 different forms of ichthyosis, the most prevalent of which is hereditary ichthyosis Vulgaris, which often manifests in the first year of life.Acquired variants of the skin condition can be brought on by several thyroid-related systemic problems, exposure to H.I.V., or Hodgkin's lymphoma. Numerous drugs, including herbal remedies for calming beverage kava, might potentially cause it.Present medical history: A 15-year female patient registered to the Skin ward (Dermat) with the main complaint of Skin that is dry, itchy, and scaly, especially on the arms all over the body. Skin that is tense, especially after a bath. Following a general check and study, ichthyosis Vulgaris was diagnosed. The most commonly prescribed treatment intervention and its consequences. The doctor interpreted Ichthyosis Vulgaris. Following a thorough examination and inquiry.Conclusion:-The following is the proposed structured symptom-based and evidence-based approach: strategy includes a guide to ichthyosis Vulgaris diagnosis and treatment. Its goal is to increase awareness about the importance of early detection and treatment of this ailment to enhance your quality of life while avoiding potential problems.
Case report on Management and Complication of Peutz Jegher Syndrome
Authors: Seema kolhe  , Pratiksha Munjewar  , Aniket Pathade
Published: November 2022

Introduction: Infrequent and characterized by mucocutaneous pigmentations, gastrointestinal polyposis, and an increased risk of malignancy, Peutz-Jeghers syndrome is an autosomal dominant genetic condition. The usual perioral macules and patches that are colored in the buccal mucosa are present in 90% of patients, and numerous but not continuously contiguous lesions, primarily in the gastrointestinal (G.I.) tract, with rarely more than 20 hamartomata's polyps, are the characteristics of Peutz-Jeghers syndrome (P.J.S.). Present complaints and Investigation:-Suddenly felt sick to my stomach and started to puke. Abdominal pain, Black stools, repeated vomiting, weight loss of 5 kg in 15 days, loss of appetite, and Intussusception were discovered during examinations in the upper small bowel. A thorough study of the gastrointestinal tract was conducted. Endoscopically, the enormous polyps of the stomach and duodenum were discovered and biopsied. Resulting of bleeding due to the G.I. polyps, she became anemic. There were polyps. Later removed endoscopically while being sedated, C.T.'s Abdomen and pelvis found multiple mildly enhanced polypoidal lesions notes attached to the pyloric part of stomach and duodenum proximal jejunal loops, similar lesions of Ascending colon, transverse colon, and advice colonoscopy. History: The patient was admitted in 2015 And Operated on 26/12/2015, the year Jejunoileal intussusception. The primary diagnosis, therapeutic intervention, and outcomes: After physical examination and investigation, Hamartomatous polyp (P-J Secondary Intussuseception ) Conclusions: The following primary complaints were the reason for the patient's hospital admission. Upon entry to the hospital, the patient's main complaint was that Peutz Jegher Syndrome was identified as the patient's condition once all investigations were complete. The patient now needs appropriate medical attention and quality nursing care.
Case report on Acute Cardiopulmonary failure with Pneumonitis with Pickwickian syndrome
Authors: Tanay Patil  , Minal Dambare  , Pratiksha Munjewar  , Aniket Pathade
Published: November 2022

INTRODUCTION: The inability of the heart to supply enough blood flow to the body's metabolic tissues is known as heart failure (H.F.). A patient's tolerance for physical activity is described by the N.Y.H.A. Classification of H.F., updated in 1994 to include objective assessments of heart function and disease. The phrase "cardiopulmonary disease" is used in medicine to refer to various dangerous diseases that affect the heart and lungs. Cardiovascular Disease (CVD) and Chronic Obstructive Pulmonary Disease (C.O.P.D.) are the two main cardiopulmonary conditions caused by cigarette use (C.O.P.D.). A severe respiratory infection brings on the lung condition known as pneumonia. The tiny sacs called alveoli that make up a healthy person's lungs are filled with air as they breathe. Pneumonia causes the alveoli to fill with pus and fluid, making breathing challenging and limiting oxygen intake. A metabolic syndrome is a group of risk factors associated with cardiovascular disease morbidity and mortality. It is often referred to as Syndrome X. (CVD). Despite being widespread, it has not received enough attention and occasionally goes unnoticed. As primary care practitioners, we must keep an eye out for these people so that early identification, intervention, and prevention can be put into practice.A Chinese lady with metabolic syndrome is described in the following paragraphs. Present complaint and investigation: on March 28, 2022, a 62-year-old female was hospitalized at A.V.B.R. Hospital with breathing difficulty, lower limb swelling, chest pain, mucus in the throat and lungs, loss of appetite, nausea, and vomiting. Twelve days have passed. Investigation: Haemoglobin is decreased by 10.7gm, WBC count 11,000 per microliter, Total R.B.C. count increased 5.84 million /cell, M.C.H. level Decreased 70fl, MCH IS DECREASE 22.8 pico-gm. Therefore CT report should be interpreted in correlation with clinical &pathological findings. PAST HISTORY: he was admitted eight days before outside the hospital for the same complaints on 26/02/2022. Pneumonia one year back for which she symptoms in 2000 for fibroid he took treatment. After the physical examination and investigation, diagnosed RESPIRATORY ACIDOSIS WITH OBSTRUCTIVE SLEEP APNEA WITH HYPERTENSION. Conclusion: He responded well to all medication and doctor care and made a good recovery.
ASSESS THE SEPARATION ANXIETY AMONG DEAF AND MUTE STUDENTS LIVING AND STUDYING IN SPECIAL SCHOOLS
Authors: Sakshi J. Patil  , Pema Chuki  , Bhushan Petkar  , Gaurav Raut  , Madhuri Shambharkar
Published: November 2022

Background: Research is aimed at studying the separation anxiety among deaf and mute students living and studying in special schools due to the internalized nature of their symptoms, anxiety disorders frequently go undiagnosed in school students. Academic performance and daily activities can be severely harmed by anxiety. Additionally, untreated anxiety over time can lead to behaviors like skipping school and eventually, early school exit. Objectives of the Study:1) Assess the separation anxiety among deaf and mute students with selected demographic variables.2) To associate separation anxiety with specific demographic variables. Materials and Methods: The purpose of this descriptive study and the goal of the research was to assess the anxiety among deaf and mute students living and studying in special schools. Based on inclusion criteria and purposeful convenient sample approaches, 52 students were chosen. The information was gathered in an organized way. Results: The goal of the research was to assess the separation anxiety among deaf and mute students living and studying in special schools. The deaf and mute students represent their separation anxiety in the form of mild separation anxiety, moderate separation anxiety, and severe separation anxiety, and the result was 92.33%, 5.75%, and 1.92% respectively. Conclusion: The researchers did a descriptive research investigation on the topic as part of their undergrad curriculum to assess the separation anxiety among deaf and mute students living and studying in a special school.