bluuebunny/crossref_metadata_2025 huggingface dataset:
Спиновый эффект Холла в поликристаллических образцах немагнитных металлов пятого и шестого периодов
Authors: Игнатьев В.К. , Перченко С.В. , Станкевич Д.А.
Published: February 2023

The paper proposed a method to estimate the coefficient of spin Hall effect for polycrystalline samples of pure nonmagnetic metals. The transverse resistivities characterizing the spin Hall effect were calculated for different metals of the 5th and 6th periods. It is shown that the result within a statistical error agrees with the experimental data.
Высокоэффективные GaInP/GaAs-фотопреобразователи лазерной линии 600 nm
Authors: Минтаиров С.А. , Малевская А.В. , Минтаиров М.А. , Нахимович М.В. , Салий Р.А. , Шварц М.З. , Калюжный Н.А.
Published: February 2023

Изготовлены оптимизированные фотопреобразователи на основе гетероструктур GaInP/GaAs, выращенных методом металлоорганической газофазной эпитаксии, для работы с лазерным излучением высокой мощности зелено-красного спектрального диапазона. Для формирования лицевой контактной сетки приборов исследованы контактные системы Au(Ge)/Ni/Au и Pd/Ge/Au. В результате фотопреобразователь лазерной линии с длиной волны 600 nm с Pd/Ge/Au-контактом демонстрировал КПД более 50% вплоть до плотности мощности падающего излучения 30 W/cm2 с максимальным значением 54.4% при 7 W/cm2. Ключевые слова: фотопреобразователь, лазерное излучение, металлоорганическая газофазная эпитаксия (МОСГФЭ), КПД, спектральная чувствительность.
Clinical Outcomes After Viewing Video Education on Danger Signs and Symptoms of Worsening Heart Failure and Self-care Actions
Authors: Albert Nancy , Babcock Carol , Gray-Leyko Anna Maria , Bena James , Morrison Shannon , Sayler Dorothy , Levay Michelle
Published: February 2023

Background

Patients with heart failure (HF) must understand subtle escalation in fatigue, dyspnea, and edema before they are triggered to control worsening status.

Objective

The aim of this paper is to examine if video education of HF danger signs or symptoms recognition and control, developed using symbolic modeling (social cognitive theory), leads to between-group differences in functional status, symptoms, and self-efficacy for managing symptoms at 30-days, all-cause, and HF-related hospitalization, emergency department visits, and death at 30, 90, and 180 days.

Methods

Using a 2-group, randomized controlled, multicenter, single-blind design, patients received video education (VE) plus usual care (UC) or UC alone before hospital discharge. VE patients also had access to content post discharge. Thirty-day functional status, fatigue, dyspnea, and self-efficacy for managing symptoms were assessed using valid, reliable tools. In the analysis, multivariable models were created to compare changes in patient-reported outcomes from baseline to 30-days post discharge and morbidity or mortality outcomes up to 180 days.

Results

Of 369 VE and 377 UC patients enrolled from 7 sites, mean age was 68.0 (SD 12.4) years, and 206 (55.9%) were male. At 30 days, there were no between-group differences in the change in functional status, fatigue, dyspnea, and self-efficacy from baseline. In multivariable analyses, between-group outcomes did not differ at 30 or 90 days. At 180 days, HF-related events and HF-related hospitalization were higher in the video group—odds ratios (95% CI): 1.42 (1.04, 1.94), P=.03; and 1.44 (1.05, 1.97), P=.03, respectively. In time-to-event adjusted analyses, video patients had earlier HF-related hospitalization, compared to UC patients—hazard ratio (95% CI) 1.32 (1.02, 1.72), P=.04.

Conclusions

Video education on recognition and control of danger signs or symptoms paradoxically increased HF-related events and hospitalization and decreased time to first HF-related hospitalization. Increased recognition of subtle HF signs or symptoms via video education is valuable but must be connected to patient or family self-care actions that reduce HF signs or symptoms.

Trial Registration

ClinicalTrials.gov NCT03657459; https://clinicaltrials.gov/ct2/show/NCT03657459

Conflicts of Interest

None declared.
Telenursing and Telemonitoring During and Beyond the COVID-19 Pandemic
Authors: Kamei Tomoko
Published: February 2023

Background

The presenter will be discussing home monitoring–based telenursing for people with chronic conditions. This technology has been implemented in home-care individuals with chronic obstructive pulmonary disease, type 2 diabetes, congestive heart failure, lung cancer, and amyotrophic lateral sclerosis, who are treated at home, including during the COVID-19 pandemic. The pandemic, which began in late 2019, has limited our everyday activities and opportunities to connect with people. Older adults with chronic conditions are most especially affected. While telenursing practice is not so familiar in the Japanese context, the Japan Academy of Home Care (2021) first defined telenursing as “information and communication technologies involving telecommunication provided by nurses.” Furthermore, we are providing seminars for the nurses and expanding their capacity on how to provide efficient telenursing support for people receiving home care.

Objective

This study aims to present effective telenursing practice examples, as well as the challenges surrounding the use of technology in care for older adults with chronic conditions during and beyond the COVID-19 pandemic.

Methods

A fully longitudinal mixed methods design was used to evaluate the physical and emotional fluctuations of people from qualitative and quantitative strands, and we integrated the results and meta-inferences.

Results

The patients showed a continuous change over time in terms of their physical and psychological status. Living with symptoms, the patients were constantly reminded of the reality of their disease and the activity limitations the pandemic brought. At times, they were able to find hope for the future by actively controlling and managing their disease, maintaining their health and physical function, and realizing that they could live a normal life. On the other hand, they experienced a loss of activity, a decline in physical function, and anxiety about the future, brought about by the pandemic. Thus, people who receive telenursing are on a dynamic disease trajectory that vacillates between hope and despair, and telenursing can help them.

Conclusions

Performing telemonitoring and telerehabilitation of older adults throughout the pandemic, as well as adapting to their physical and emotional fluctuations, will improve their quality of life.

Conflicts of Interest

None declared.
Automated Classification of Lay Health Articles Using Natural Language Processing: A Case Study on Pregnancy Health and Postpartum Depression (Preprint)
Authors: Patra Braja Gopal , Sun Zhaoyi , Cheng Zilin , Reddy Jagadeesh Kumar Praneet Kasi , Altammami Abdullah , Liu Yiyang , Joly Rochelle , Jedlicka Caroline , Delgado Diana , Pathak Jyotishman , Peng Yifan , Zhang Yiye
Published: February 2023

BACKGROUND

Creating credible and engaging health communication materials is knowledge- and labor-intensive.

OBJECTIVE

We propose a low-cost alternative by classifying lay health articles by relevance and topic using natural language processing (NLP).

METHODS

With postpartum depression as a case study, we conducted a manual review of online lay articles to classify articles on their relevance to pregnancy and topics. To scale the classification process on relevance and topics, we built models using Bidirectional Encoder Representations from Transformers (BERT), Generative Pre-trained Transformer model (ChatGPT), and Random Forest.

RESULTS

The gold standard corpus included 392 articles. A BERT-based model performed best (F1= 0.974) in an end-to-end classification of relevance and topics. In a two-step approach, given articles already classified as related to pregnancy, ChatGPT was best (F1 = 0.972) in classifying topics.

CONCLUSIONS

With NLP, we may repurpose lay reading materials as low-cost and easily accessible health education and communication sources.
What do we know about Health Literacy research during COVID-19: a bibliometric review (Preprint)
Authors: Lv Hewu
Published: February 2023

BACKGROUND

Health literacy is playing an important role during the COVID-19 pandemic. Health literacy have recently become popular research themes. However, there are no published bibliometric reports that have analyzed the corresponding scientific literature in relation to the application of these technologies in medicine. However, there are no published bibliometric reports analyzing the scientific literature on health literacy related to COVID-19.

OBJECTIVE

We used a bibliometric approach to identify and analyze the scientific literature on health literacy during COVID-19, revealing the country, author, journal, disciplinary, keywords and highly cited documents of health literacy research. We further aimed to capture and describe the most themes and future research frontiers in health literacy research.

METHODS

The Web of Science Core Collection (WoSSC) dataset was searched to identify relevant papers on health literacy during COVID-19. Presents a systematic mapping of the health literacy research during COVID-19 period using VOSviewer and CiteSpace. Bibliometric visualisation based on co-word analysis, a method sensitive to the configuration of health literacy networks of knowledge, is employed to create a semantic topography during COVID-19 period literature.

RESULTS

The analysis was based on data from 579 peer-reviewed publications written in English between 2020 and 2022 (retrieved on January 11, 2023). Major research themes were strong associations with vaccine hesitancy, social media information veracity, COVID-19 prevention management, and public mental health. Dealing with the relationship between health literacy and COVID-19 vaccine hesitation is the future research frontier in this field. We have made statistics on the country, author, journal, disciplinary, keywords and highly cited documents of health literacy research.

CONCLUSIONS

The bibliometric analysis conducted clearly reveals the themes and frontiers of research on health literacy during COVID-19. It is important to improve the e-health literacy of the public so that they can properly use social media to distinguish true from false information about COVID-19, the government can improve the efficiency of epidemic management and ensure the effective prevention of mental health problems caused by COVID-19.
“Writing for Healing” Pembuatan Website, Buku, dan Video Edukatif dan Inspiratif untuk Pencegahan, Pengurangan Penularan serta Kecemasan terkait COVID-19
Authors: Vardhani Nabilla Kusuma , Handayani Andri , Nugraha Cisya Dewantara , Ambarwati Dewi Cahya , Yuanti Erlin Estiana , Makhasi Ghifari Yuristiadhi Masyhari , Nugraheni Nur Endah , Nuraniwati Tri , Santoso Dian Budi , Pratiwi Rita Dian , Huda Irkham , Putra Jimmy Trio
Published: February 2023

COVID-19 pandemic has an impact on people's lives in all sectors. Adaptation to go through difficult times is needed so that all parties can survive and find solutions to various difficulties experienced. One way that can be done is by motivating others through writing activities. Karen A. Baikie and Kay Wilhelm (2005) found that writing about traumatic, stressful, and emotional events has an impact on improving physical and psychological health in both clinical and non-clinical populations. Besides, miksilva.com also writes that writing can also heal writers and readers from life pressures and feelings of anxiety. This community service focuses on creating educational and inspiring websites, books, and videos to prevent and reduce transmission and anxiety related to COVID-19. The team took the theme "Writing for Healing" (WFH) to create websites and books. On the website, there are menus for Home, About, Story, and Videos. The video produced contains education about COVID-19. From this activity, there were 65 articles collected up to June 14, 2020. The authors came from various cities and regions, including Yogyakarta, Surabaya, Cirebon, Bengkulu, Bogor, South Kalimantan, North Jakarta, Jember, Purbalingga, Lumajang, Tangerang, Bali, Sampang, Batam, Makassar, South Jakarta, etc. These writings were published on the website wfh.sv.ugm.ac.id, and 33 of the best writings were made into a book published by BPP UGM. As for the video, the team has made two videos entitled 'Apa Itu Kenormalan Baru' and 'Stay Happy, Berkawan dengan Pandemi'. The impact given from this program can be seen from the number of writers, readers, website visitors, and video viewers that have been broadcasted on the website and YouTube.
Evaluating the Potential of Brown Sugar Product as An Effort to Increase the Economic Welfare of Coconut Farmers in Sidorejo Village, Kapenewon Lendah, Kabupaten Kulon Progo
Authors: Pramuditya Fani , Wardhana Leo Indra , Akbar Saiqa Ilham , Satrianto Elton Buyung
Published: February 2023

This study aims to give innovation and value added to the brown sugar produced by the community in Sidorejo Village. The purpose is to provide a better income for the coconut farmer  as well as to optimize the roles of BUMDES Binangun Dadi Maju as an economic catalyst. This project was conducted in Desa Sidorejo, Kapenemon Lendah, Kabupaten Kulon Progo, Daerah Istimewa Yogyakarta. There are three stages applied in this program i.e.: preparation, application and evaluation. Recommendations and guidance were given to the farmer and BUMDES to develop the brown sugar product and to produce the liquid brown sugar product. The new product development is still under evaluation for the commercial purpose.
Developing a Clinical Counselor Identity: An Interview with Courtnee Reis, MS, LPCC
Authors: Stewart Daniel
Published: February 2023

The role and function of a professional clinical counselor require a breadth of knowledge and skill. But it is more than just knowing a theory or how to implement an intervention; clinical counselors need to develop a counselor identity that is centered on cultural sensitivity, cultural humility, and social justice. Regardless of the types of services clinical counselors are offering, whether it’s individual counseling, group counseling, art therapy, or psychosocial evaluations, who we are as a profession needs to be expressed in every aspect of our work. The guiding principle of ethical practice should be the platform on which our identity as counselors is built upon. I had the opportunity to interview Courtnee Reis, a Licensed Professional Clinical Counselor in California who provides services to clients from diverse backgrounds drawing upon post-modern narrative therapy and strengths-based practices. Her work demonstrates the ever-growing need to provide competent and ethical services while holding space for each of our clients to live a meaningful, productive, and beneficial life. The following is an account of our interview.
Gilaki: From Language Regimes into Minoritizing
Authors: Roodsari Sedighe Zamani
Published: February 2023

The effects of language contact depend on many different factors, such as language prestige, government and community support, people’s preference, linguistic proximity of the languages, among other things. As such, while there are some broad potentially predictable outcomes in situations of language contact, it is important to analyze each language contact situation in its own context. The aim of this study is to examine the maintenance and social function of Gilaki in the city of Lahijan located in the province Gilan, Iran. This study also poses the question whether Gilaki is at risk of becoming an endangered language. The participants (N=395), students at a language center and their families, completed a questionnaire with 36 questions. The participants were grouped according to gender, age, educational background, occupation, and spouse’s mother tongue based on a self-reported data collection style. The questionnaire, inspired by Parasher’s model (1980), examined the participants’ language use and preference in six social domains of family, friendship, neighborhood, transaction, education, and administration. The findings show statistically significant differences in the participants’ preference toward Persian in all six social domains. This study contributes to the body of work in language contact of lesser analyzed languages and sheds light on the trajectory of minoritized languages.
IN VITRO ANTI-DIABETIC ACTIVITY PUNICA GRANATUM LINN LEAF EXTRACT
Authors: PALANISAMY VAIJAYANTHIMALA , A MUTHUMANIKANDAN , BALAKRISHNAN SANGAMESWARAN
Published: February 2023

Objective: The present investigation deals with the study of in vitro anti-diabetic activity by inhibition of intestinal absorption of glucose by alpha-amylase method. Punica granatum L plant is a fruit-bearing deciduous shrub. It is used in the treatment of pneumonia as a bitter tonic also used in the treatment of flu, mouth and lip infection, antifungal, and immunosuppressant which used to treat heart disorders, stomach disorders, dental care, anemia, osteoarthritis, and anti-diabetic.
The intestinal digestive enzymes such as alpha-glucosidase and alpha-amylase have played a vital role in carbohydrate digestion that these can be an important approach in managing of blood glucose.
Methods: The air-dried powder of P. granatum Linn (leaf part) was extracted using a Soxhlet apparatus with ethanol extract of Psidium guajava (EEPG) and water aqueous extract of P. granatum (AEPG) as solvent. The extracts were concentrated under reduced pressure. The activities were carried out using the following concentration (10, 20, 30, 40, and 50 μg/mL) and compared with Acarbose as standard drug. It has significant in vitro anti-diabetic in alpha-amylase method.
Results: The extract of P. granatum possessed significant anti-diabetic property in EEPG than compared to AEPG.
Conclusion: Activity may be due to the presence of chemical profile such as glycosides, flavonoids, and terpenoids. The results of the study have suggested in the use of P. granatum Linn. as a potent anti-diabetic in several applications.
AN EXTENSIVE REVIEW ON MEDICINAL PLANTS IN THE SPECIAL CONTEXT OF ECONOMIC IMPORTANCE
Authors: NATH RAJAT , KITYANIA SIBASHISH , NATH DEEPA , TALKUDAR ANUPAM DAS , SARMA GADAPANI
Published: February 2023

Our health-care system would be incomplete without the use of medicinal herbs. In the days before modern medicine, several communities created medical knowledge systems known as “traditional medicine,” “indigenous medicine,” or “folk medicine.” The medicinal properties of plants and plant-based products are widely accepted. There are a variety of medical approaches available across the world, including allopathic, homoeopathic, Ayurvedic, and Chinese. The developed communities each have their own Materia Medica, which compiles thorough data on many plants used as medicines. According to current estimations from the field of botany, there are somewhere between 2,50,000 and 3,50,000 distinct plant species in existence. It is estimated that 35,000 unique species are used to cure a wide range of ailments in diverse places throughout the world. Based on general popularity among all ages, phytopharmaceuticals are an integral part of worldwide business and the global economy. According to a globe news wire study, the global herbal medicine market is estimated to be 550 billion dollars by 2030, up from 83 billion dollars in 2019. China and India lead the global herb market. China exports 120,000 tonnes of herbal remedies annually, followed by India with 32,000 tonnes. Europe is the world’s largest importer of medicinal plants (MP), taking in over 400,000 tonnes annually to fulfill local demand. In this review, we have discussed about the MP and their economic importance in global market.
DEVELOPMENT AND QUALITY EVALUATION OF BIODEGRADABLE EDIBLE CUTLERY: A REPLACEMENT FOR A CONVENTIONAL ONE
Authors: THAGUNNA BISHAL , SHRESTHA GRISHMA , KARKI RACHANA , BARAL KABUL , KAUR JASPREET
Published: February 2023

Objectives: The objectives of this research were to develop a safe, sustainable alternative to plastic cutlery using water, wheat flour, finger millet, rice flour, water, jaggery, oil, and salt in varying amounts.
Methods: Edible cutlery was manufactured using a manual method by putting the dough on a steel spoon and cooking bowl and baking it at 180°C for 40 min and evaluating their proximate analysis, sensory attributes, water absorption capacity, and biodegradable test.
Results: Sample S3 was found to be best in terms of nutrition including moisture, protein, fiber, fat, and ash (4.8, 7.23, 2.3, 3.7, and 1.97%). Carbohydrate content was found higher in S1 compared to S2 and S3 which are 90.43%. Similarly, S1 had the highest overall sensory attributes including color, appearance, texture, flavor, odor, and overall acceptability (7.64, 7.82, 6.91, 7.0, 6.9, and 7.45%) and has a high amount of water absorption capacity (31.59%) compared to S2 and S3.
Conclusions: Biodegradable and edible cutlery would provide a completely new perspective and alternative to the fight against plastic pollution.
EFFECT OF METFORMIN ON HEART RATE VARIABILITY IN NEWLY DIAGNOSED TYPE 2 DIABETES MELLITUS PATIENTS AT A TERTIARY CARE HOSPITAL
Authors: RATHOD KHUSHBU , YADAV PREETI , CHAUDHARI MAYUR , VASAVA ASHVIN , PATEL MRUGANK
Published: February 2023

Objectives: There is a worldwide epidemic of type 2 diabetes mellitus (T2DM). It is associated with cardiovascular autonomic neuropathy. Heart rate variability (HRV) is the gold standard for its measurement. Thus, effect of metformin therapy on HRV was evaluated in newly diagnosed T2DM patients.
Methods: This was a prospective and observational study carried out from January 2020 to September 2021 in the medicine outpatient department of a tertiary care hospital in Gujarat, India. The study included newly diagnosed T2DM patients of both genders aged 18–70 years. Baseline HRV parameters were recorded by performing electrocardiogram for a fixed duration of 5 min. Follow-up was done after 6 months of metformin 500 mg monotherapy. Time domain analysis was done using square root of mean square of successive R-R interval difference (RMSSD) and frequency domain analysis was done using low-frequency/high-frequency (LF/HF) ratio. Paired t-test was used for analysis. p<0.05 was considered statistically significant.
Results: Total 30 patients were included in the study. The average age of participants was 43.5±4.5 years. The highest number of patients were from age group between 41 and 50 years (33.3%). There were more number of females (56.7%) compared to males (43.3%). There was an increase in the RMSSD value after metformin treatment, but it was not statistically significant (p=0.308). In frequency domain analysis, there was no significant improvement in LF, HF, as well as LF/HF ratio (p=0.655).
Conclusion: There was a minor improvement in HRV parameters after 6 months of metformin therapy, but it was not statistically significant. Further studies with larger sample size should be planned with one or more oral hypoglycemics.
A STUDY ON THE OCULAR MANIFESTATIONS OF ROAD TRAFFIC ACCIDENT CASES ATTENDING GOVERNMENT REGIONAL EYE HOSPITAL
Authors: KRISHNA RAJIV
Published: February 2023

Objectives: Road traffic accidents (RTA) are increasing day by day because of rapid increase in India’s population resulting in a greater number of people commuting. Added to this due to busy schedules of both employees and students there is enormous rise in RTA. The aim of the study is to analyze various ocular manifestations of eye injuries due to RTA attending an eye hospital.
Methods: This study is cross-sectional study. 144 patients attending Regional Eye Hospital from January 2022 to June 2022 with various RTA were examined clinically by noting Best corrected visual acuity, Anterior segment, posterior segment examination, and Radiological imaging. Data were analyzed using Microsoft excel 2019 software.
Results: In this study, nearly 50% of subjects were in 16–35 years age group. Two-thirds in the study group were males. People from all walks of lives were involved in RTA. About 35% of the study group were commuting in a two-wheeler. More than 50% of the patients presented between 24 and 72 h after RTA. Majority of patients presented with some visual loss. Almost all the patients presented with some form of eyelids involvement like bruising or edema. Most common anterior segment finding was subconjunctival hemorrhage.
Conclusion: Ocular injuries due to RTA cause significant morbidity in certain individuals. Frequent commuters are more prone for RTA. Strictly abiding traffic rules and wearing protective gears will significantly reduce ocular trauma.
COMPARISON OF EFFICACY OF TAMSULOSIN, ALFUZOSIN, AND SILODOSIN IN THE MANAGEMENT OF BENIGN PROSTATIC HYPERPLASIA
Authors: RETNAYYAN APARNA , SREEDHARAN SYAM , RETHINASWAMY FREDRICK PAUL , NARAYAN NAMPOOTHIRI HARISANKAR KARAKKAATTILLAM , MATHEW BRIGHTY
Published: February 2023

Objectives: This study was done to determine the efficacy of alpha-1 adrenoceptor blockers such as tamsulosin, alfuzosin, and silodosin in patients with the lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) over 6 months by assessing change in international prostate symptom score (IPSS), quality of life scale for urinary symptoms (Bother score), and improvement in peak urine flow rate (Qmax) from baseline. We also tried to identify any adverse drug reactions (ADRs) caused by these drugs.
Methods: A prospective observational study was conducted in 291 patients with LUTS secondary to BPH attending urology outpatient department of a tertiary care center for 1 year. Ninety-seven patients in each group received tamsulosin, alfuzosin, or silodosin once daily. IPSS, Qmax, and the quality of life scale for urinary symptoms by Bother score were assessed at 1st, 3rd, and 6th month of treatment period. ADR was noted and recorded in ADR reporting form.
Results: IPSS, mean bother score, and mean Qmax showed significant improvement from the baseline in each follow-up visit at 1, 3, and 6 months for all the three groups, but maximum was for alfuzosin and was found to be statistically significant (p<0.001). Two patients developed adverse drug reaction during the study; asthenia in tamsulosin group and hypotension in Silodosin group.
Conclusion: Patients on alfuzosin showed maximum improvement in the values of IPSS, Bother score, and Qmax in BPH patients as compared to tamsulosin and silodosin. Alfuzosin would be a better choice in the treatment of LUTS due to BPH.
A CROSS-SECTIONAL STUDY ON THE ASSESSMENT OF KNOWLEDGE AND METHODS PRACTICED IN DISINFECTING AND DISPOSAL OF FACEMASKS AMONG THE GENERAL PUBLIC
Authors: SARJI PAVITHRA S , POOJARY NAGARATHNA , NEKKANTI VINEELA , SRINIVASAN R
Published: February 2023

Objectives: The vast amount of facemasks generated as waste should be disposed of appropriately and responsibly to prevent adverse effects on health and the environment. This study aims to assess the knowledge and methods commonly practiced by the public to disinfect and dispose of used facemasks.
Methods: A cross-sectional study was conducted from June 2021 to December 2021 in the South Part of Karnataka using a face-validated questionnaire. The questionnaire included subject demographic details and methods to disinfect and dispose of masks. The data were recorded and analyzed using Microsoft Excel.
Results: A total of (n=501) participants took part in the study. This study observed that the most commonly practiced method was to wash the masks with specific cleaners (n=259, 53%). We also assessed knowledge regarding the methods of disposal of a mask. The majority of the participants in our study are aware of the correct method for disposal of used masks(n=342, 68.26%), while (n=159, 31.73%) of subjects are not aware of the right facemask disposal method. Subjects who are educated (p=0.008) and regular mask users (p=0.011) are aware of the right method for mask disposal.
Conclusion: Many people are unaware of the correct disposal methods. Hence, Manufacturers and Scientists should identify an effective way to disinfect and dispose of used masks and educate the public to practice the proper method of facemask disposal.
EVALUATION OF MODIFIED NITRITE TEST AS A DIAGNOSTIC TEST IN URINARY TRACT INFECTION OF CHILDREN
Authors: JAIN PUNEET , MALVIA SUNNY , KHAN NIHA
Published: February 2023

Objective: Urinary tract infection (UTI) is common infection in children. Urine culture is the gold standard method for diagnosing urine infection but it takes more than 48 h to give results. The objective is to evaluate the diagnostic ability of modified nitrite test as a rapid diagnostic screening test for diagnosis of UTI in children.
Methods: An observational and cross-sectional study was conducted in a tertiary care hospital in Udaipur over a period of 1 year. Children aged up to 60 months with suspected UTI were enrolled in the study. Children with congenital urogenital anomalies and prior antibiotic treatment were excluded from the study. Urine culture and modified nitrite test was done for every children.
Results: Ninety children with suspected UTI were enrolled in the study. Urine culture was positive in 14 (15.55%) out of 90 urine samples. When modified nitrite test was compared to positive urine culture, true positives were 9 and 1 was false positive. Sensitivity, Specificity, PPV, NPV, and Accuracy was 64.29%, 98.68%, 90%, 93.75%, and 93.33%, respectively.
Conclusion: Sensitivity and specificity of modified nitrite test are good enough as a diagnostic test for detection of UTI. It can be used as a point of care test for rapid screening and identifying the cases.
PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANTIOXIDANT ACTIVITY OF SYZYGIUM JAMBOS FRUIT AND ITS SEED
Authors: DUTTA SUCHANDRA , HALDER SHREYASI , KHALED KAZI LAYLA
Published: February 2023

Objective: This study was designed to investigate the phytochemical screening of different solvent extracts, total phenolic, and flavonoid content and 13 different methods of in vitro antioxidant activity of Syzygium jambos fruit and its seed.
Methods: The antioxidant activity of the methanolic extract of S. jambos fruit and its seed was carried out by 2,2-diphenyl-1-picrylhydrazyl, ABTS radical scavenging activity, site-specific and non-site-specific hydroxyl radical scavenging activity, superoxide radical scavenging, nitric oxide radical scavenging, potassium ferricyanide reducing assay, ferric thiocyanate, total antioxidant capacity, hydrogen peroxide radical scavenging, thiobarbituric acid reactive substances, ferric reducing antioxidant power, and cupric reducing antioxidant Cusing standard procedures.
Results: The preliminary phytochemical screening has revealed the presence of phenolics, flavonoids, alkaloids, tannin, saponin, and carbohydratesexcept for steroids and terpenoids. The total phenolic content and flavonoid content of S. jambos fruit and its seed was found to be (S. jambos fruit – 127.61 mg of GAE/100 g, S. jambos seed – 217.34 mg of GAE/100 g) and (S. jambos fruit – 8.64 mg of QE/100 g, S. jambos seed – 15.97 mg of QE/100 g), respectively. The fruit and its seed also showed significantly strong antioxidant activity in different in vitro methods.
Conclusion: The Syzygium jambos fruit and its seed have anadequate quantity of phytochemicals that act as an antioxidant and scavenge free radicals efficiently. Hence, the fruit and its seed may be considered as effective in the prevention and treatment of oxidative stress-induced diseases such as diabetes, cardiovascular diseases, cancer, arthritis, gout, neurodegenerative diseases, and respiratory tract infections.
INCIDENCE AND RISK FACTORS FOR DRY EYE DISEASE IN A TERTIARY HOSPITAL IN NORTH CENTRAL INDIA
Authors: MANOJ GOVILA , MOHAN VERMA KAMAL , NEYAZ HASAN SYED , RAM MILAN PRASOT
Published: February 2023

Objectives: Dry eye disease (DED is a severe tear insufficiency condition that affects millions of people worldwide. Dry eye refers to conditions of the tear film brought on by decreased tear production and/or excessive tear evaporation. The study’s objective was to compile data on the incidence of DED and associated risk factors.
Methods: The government hospital of Uttar Pradesh (India) served as the study’s site for this cross-sectional and observational study. Clinical observation and the ocular surface disease index survey were used to assess the aim of the study.
Results: Patients were screened in total, 652. The incidence of DED was reported in 267 (40.9%) individuals. There were 130 DED patients (48.7%) above the age of 40, followed by those between the ages of 21 and 40 (47.2%). Both genders were equally impacted, with men (50.2%) and women (49.2%). Out of 267 DED patients, 128 (47.9%) had a desk job with a computer. Among the patients, 57 (21.3%) had mild DED, 74 (27.7%) had moderate DED, and 136 (50.9%) had severe DED. The severe DED also showed independent association between the desk job with a computer (Odds Ratio [OR]; 2.782, 95% confidence interval [CI]: 1.694–4.568, p<0.001), cigarette smoking (OR; 1.849, 95% CI: 1.135–3.014, p=0.014), and use of contact lens (OR; 1.972, 95% CI: 1.206–3.223, p=0.007).
Conclusion: The frequency of DED is high in Uttar Pradesh. The illness is particularly prevalent in older people, computer-using desk workers, smokers, and contact lens wearers.
PRESCRIBING PATTERN OF NUTRACEUTICALS IN ONCOLOGY: AN OBSERVATIONAL STUDY
Authors: KHAJURIA KANIKA , GUPTA SEEMA , SHARMA RAHUL , KHAJURIA VIJAY
Published: February 2023

Introduction: Nutraceuticals are products found in foods and fruits that are also used as medicines other than being used for nutrition. They provide physiological benefits and protection against chronic diseases. They include minerals, vitamins, amino acids, essential fatty acids, and medicinal herbs or other dietary substances used as supplements, for example, polyphenols, quercetin, co-enzyme Q, and genistein are in use due to their chemopreventive potential.
Aim of Study: The aim of this study was to examine the prescribing pattern of nutraceuticals in cancer patients.
Methods: The present cross-sectional and observational study was conducted in the outpatient department (OPD) of Oncology of GMC Jammu after getting approval from the Institutional Ethics Committee. Patients of either gender and diagnosed with carcinoma attending oncology OPD were included in the study. Fifty prescription slips were evaluated for the prescribing pattern of nutraceuticals. The data were analyzed in percentages.
Results: Most of the patients were prescribed more than one nutraceutical. Most commonly prescribed nutraceuticals were vitamins (44%) which included vitamin A, B complex, C, and D followed by minerals (36%), essential amino acids (12%), beta-carotene (8%), coenzyme Q (6%), lycopene (6%), curcumin (4%), and wheatgrass (2%).
Conclusion: Nutraceuticals are being increasingly prescribed to cancer patients. In our study, vitamins were the most commonly prescribed nutraceuticals. Most of them have antioxidant potential. Nutraceutical use may increase in the future due to their safety and therapeutic effects.
CECT IN THE ADRENOCORTICAL CARCINOMAS: RECOGNIZING THE TYPICAL MORPHOLOGICAL FEATURES
Authors: KRITIKAL  , SHARMA RAJARAM , LODHA SAMBHAV , THAKKAR HEMANGINI , BADHE PADMA
Published: February 2023

Objectives: This study was characterization of adrenal masses on computer tomography (CT) using shape, size, and enhancement patterns.
Methods: It is a retrospective study of 86 adrenal masses with morphological differences in the appearance and enhancement patterns (histopathologically proven 36 pheochromocytoma [PCCs], 26 adrenal cortical carcinoma [ACCs], one lymphoma, 22 metastases, and one schwannoma). Two experienced radiologists who were unaware of the histopathological diagnosis reviewed the computed tomography scans, morphological parameters had been noted, along with attenuations measured in Hounsfield units for all the phases of contrast-enhanced computed tomography.
Results: Necrosis had been seen in all the cases of ACCs with a loss of adeniform shape. ACCs were significantly less enhancing in arterial phase and venous phase than PCC; however, no significant difference was seen with lymphomas, metastasis, and schwannoma. 25/33 (75.5%) ACC showed heterogeneous enhancement (due to the presence of necrosis) in the VP.
Conclusion: Heterogenous architecture with a size of more than 5 cm is relatively specific for diagnosing ACC. No specific enhancement pattern could well differentiate ACC from lymphoma, metastases, and schwannoma.
A COMPARATIVE STUDY TO DETERMINE THE EFFECTS OF VARIABLE CONCENTRATIONS AND DIFFERENT ROUTES OF ADMINISTRATION OF LIDOCAINE IN SUPPRESSING COUGH AND ON HEMODYNAMIC RESPONSE DURING EXTUBATION IN PEDIATRIC AGE GROUP: AN OBSERVATIONAL PROSPECTIVE STUDY
Authors: HAFIZ NIDHA , FAYAZ SUMEERA , TALI SHOWKAT HUSSAIN , IRSHAD SHEIKH , IQBAL MALIK ZAFAR
Published: February 2023

Objectives: The objectives of this study were to compare the effects of different concentrations of lidocaine (2% endotracheal [ET] spray; 10% ET spray; and 2% intravenous [IV]) in suppressing cough and on hemodynamic response during extubation in pediatric age groups; an observational prospective study.
Methods: Ninety patients were enrolled for the study and divided into three groups. In Group A, patients were administered (1 mg/kg) of 2% lidocaine ET spray 5 min before extubation; in Group B, patients were administered (1 mg/kg) of 10% lidocaine ET spray 5 min before extubation; and in Group C patients were administered (1 mg/kg) 2% lidocaine IV 3 min before extubation. The three groups were compared for hemodynamic parameters, incidence of cough, breathing pattern, and need for continuous positive airway pressure (CPAP).
Results: There was significant attenuation of hemodynamic parameters and less incidence of cough and labored breathing in patient receiving either 10% ET or 2% IV lidocaine. As compared to 2% ET lidocaine, requirement of CPAP support was less in patients who received 10% lidocaine. Patients who were administered 2% IV lidocaine did not receive any CPAP support postextubation.
Conclusion: As compared to 2% lidocaine spray postextubation, both 10% lidocaine spray and 2% IV lidocaine postextubation have significantly positive effect on suppression of cough and on hemodynamic parameters.
A Review Paper on Replacement of Fine Aggregate, Coarse Aggregate and Cementitious Material in Conventional Concrete: A Critical Review
Authors: Chopade Gunita , Deshpande Dr. Girija , Pawar Prof. Ramatai
Published: February 2023

Abstract: The production of plastic is increasing at a faster rate. It is very difficult to dispose this plastic waste as it creates environmental pollution. Plastic bottles usually take thousands of years to degrade and produce toxic fumes when incinerated. For solving this problem, construction industry can take a step to utilize this plastic waste as a substitute for aggregates. By replacing coarse aggregate as well as fine aggregate with waste plastic known as green innovation. As the years go by, waste plastic increases day by day, since most of the plastic used by human is non-bio-degradable. The idea behind this review is to identify research done by the researchers who uses recyclable material such as plastic obtained mostly from waste plastic that the people had generated around the world by utilisation of waste plastic in becoming of construction materials in order to overcome the environment problem that the society are facing. This paper aim to review the using of waste plastic to replace fine and coarse aggregate and stated the mechanical properties of the concrete. With different percentage replacement of aggregates will affect the different properties such as slump, compressive strength and ultimate strength of the concrete and compare with the control sample in order to find the suitable percentage of the waste plastic to replacement of aggregates for the concrete used. It was found that plastic as replacement for fine and coarse aggregate both have has lower compressive quality of the concrete, almost the same or lower slump test value for ordinary concrete and waste plastic concrete and lower density for the waste plastic concrete compare to the ordinary concrete.
Development of biodiversity enrichment e-module fauna Gembira Loka Zoo for high school students
Authors: Nurandari Bellamerna Dwi Nawangsih , Triatmanto T.
Published: February 2023

The existence of contextual learning resources that are able to accommodate students' enrichment materials independently is still not found too much. The aims of this study were to: 1) examine the diversity of fauna at Gembira Loka Zoo; and 2) developing an e-module for material enrichment on the topic of biodiversity by utilizing the results of research on faunal diversity at Gembira Loka Zoo. This Research and Development (RnD) used three main stages of the 4D model, namely define, design, and develop. The results showed that at Gembira Loka Zoo there were 88 types of fauna, including Class Gnathostomata, Class Amphibia, Reptiles, Aves, and Mammals, then the conservation agency used SEAZA guidelines for the welfare and care of the fauna. The data is then developed into an e-module for the enrichment of fauna biodiversity which has the potential as a learning resource. The e-modules that have been compiled are considered feasible by material experts, media, and educators to be used on the correctness of the concept as well as aspects of content, appearance, graphics, programming, language, and independent learning. The compiled e-modules can also be read and considered attractive by students in the aspects of content, appearance, programming, language, and independent learning. The modules that have been developed through this research are expected to be used for biology enrichment in various schools in Yogyakarta.
Mediating Effect of Cost on the Relationship between Growth Mindset and Student Engagement of College Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Soon-Jung , Yoon Mi-Sun
Published: February 2023

Objectives This research aimed to examine the direct and indirect effects of growth mindset and task cost(effort cost, opportunity cost, emotional cost, ego cost) on the student engagement of college students.
Methods For this study, data were collected from 323 students through a self-report questionnaire of research variables from College in Gyeongbuk province. Data in this study were analyzed using SPSS 22.0 and AMOS 23.0 programs. First, after conducting descriptive statistics and correlation analysis between major variables, confirmatory factor analysis was conducted to verify the validity of the measurement model. Second, a structural equation model analysis was conducted to verify the structural relationship between major variables. Third, bootstrapping analysis was performed by setting phantom variables to verify the significance of multi-parallel mediating effects.
Results The research results are as follows. First, the growth mindset was significantly positive in student engagement and effort cost, while negative in emotional cost. Second, effort cost was significantly positive, while emotional cost was significantly negative in student engagement. Third, it was found to have statically partial mediating effects both effort cost and emotional cost in the path between growth mindset and student participation.
Conclusions This study is meaningful in that it provides basic data to suggest effective student engagement in consideration of the positive and negative psychological constructs of college students.
Prevalence and Predictors of Increased and Hazardous Alcohol Consumption in a Cohort of Older South Australian Men during COVID-19 Restrictions
Authors: Nankivell Murray E. , Antwerpen Natasha van , Turnbull Deborah , Gil Tiffany K. , Martin Sean A. , Opozda Melissa J.
Published: February 2023

Background:

Increasing levels of risky alcohol consumption in older men observed in many countries, combined with trends for increased alcohol-related misuse by men during COVID, indicate a need to examine alcohol use by older men during the pandemic.

Aim:

To examine the prevalence and predictors of increased and hazardous alcohol consumption in older South Australian men during COVID-19 restrictions.

Method:

Data collected in the latest (eighth) wave of the Men Androgen Inflammation Lifestyle Environment and Stress (MAILES) cohort study were interrogated. Participants were 746 community-dwelling older men (mean age 69 years) who completed a self-report survey on mental health, coping, COVID-related worries, and alcohol consumption during pandemic restrictions. Alcohol-related items asked about changes to overall consumption (analysed as increased vs. decreased/same) and number of standard drinks per occasion (analysed as <5 drinks [not hazardous consumption] vs. 5+ drinks [hazardous]). Two hierarchical binary logistic regressions were conducted to explore predictors of increased and hazardous alcohol intake.

Results:

Eight percent of men reported increased alcohol intake and nine percent reported hazardous alcohol consumption during COVID-19 restrictions. Being in a younger age group (‘younger old’; OR=0.46, 95%CI=1.03, 2.28), having mild to severe depressive symptoms (OR=1.39, 95%CI=1.10, 5.05), and greater concern about becoming sick with COVID-19 (OR=1.52, 95%CI=1.03, 2.28) were predictive of increased alcohol consumption during restrictions. Younger age group (OR=0.46, 95%CI=0.34, 0.62) and greater concern about becoming sick with COVID-19 (OR=1.67, 95%CI=1.13, 2.51) were also predictive of hazardous alcohol consumption during this time.

Discussion:

Men participating in longitudinal health study follow-ups may be less inclined to engage in unhelpful coping behaviours such as problematic alcohol use. Clinicians should regularly screen older men for risky alcohol consumption; a particular focus on screening ‘younger old’ men, those with more significant concerns around COVID-19, and those with depression symptoms may be warranted.
Advancement of Phage Therapy Approaches in The Battle of Multi-Drug Resistance: A Review
Authors: Kumari Punam , Chakraborty Tamalika , Ghosh Sutripto
Published: February 2023

One of the most significant issues faced by humanity today is antibiotic resistance. Drugs are used in such vast amounts for human health, aquatic life, and agricultural animals that harmful bacteria have developed antibiotic resistance to various antibiotics. Further, the usage of antibiotics is increasing because of situations such as increased infections and chronic diseases that need antimicrobial treatment. Since antimicrobial resistance is rising, it is necessary to take action to help reduce and eliminate infectious diseases and ensure animal and human health. Because of this, many attempts are being made to tackle multi-drugresistant bacteria. Among the many advanced techniques that are occurring, the use of phage therapy is one such emerging procedure. The main aim of this prospective review is to identify the various new phage formulations available as a potential therapeutic intervention to combat multidrug resistance among bacteria and the objective is to identify the various reasons associated with the induction of the phenomenon of "multidrug resistance" among different bacteria, focusing on the use of phage therapy, its advantages as well as disadvantages over antibiotics as a possible therapeutic intervention. Various phage formulations, such as phage cocktails with antibiotics, nanoparticles, phage-delivering hydrogels, and many more, are emerging formulations that have successful results in fighting against multi-drug-resistant bacteria. Commercial phage solutions have helped combat antimicrobial resistance in poultry and livestock farms, improving everyone's health worldwide. As a result, this study shall serve as a source of information and understanding of the concerns mentioned above for the entirety of society and every human community.