bluuebunny/crossref_metadata_2025 huggingface dataset:
First record of the dinoflagellate Prorocentrum panamense (Prorocentrales, dinophyceae) in the Mexican Pacific from the Archipiélago de Revillagigedo
Authors: Gárate Lizárraga Ismael , González -Armas Rogelio
Published: January 2021

The dinoflagellate Prorocentrum panamense is reported for the first time on the Pacific coast of Mexico. Ten cells of P. panamense were found in network samples from surface waters in three islands of the Revillagigedo Archipelago where samples were collected in March 2017. The sampling sites They had a depth of approximately 60-70 m and the surface temperature of the water was between 21 and 23 ºC.
Synonymy of Dinoflagellates with basket-like endoskeletons: Monaster, Amphilothus and Achradina (Amphilothales, Dinophyceae)
Authors: Gomez Fernando
Published: January 2021

The basket-like skeleton-bearing dinoflagellates have been divided into three genera: the little-known Monaster as having a skeleton with longitudinal ribs in the epitheca, Amphilothus with a dense and geometric skeletal tessellation in the epitheca, and Achradina with characteristics intermediate between the other two genera. Cells of different sizes and morphologies corresponding to these genera co-occurred within the same samples from the Mediterranean Sea and South Atlantic Ocean. During cell division, a bigger daughter cell kept the endoskeleton, while the smaller daughter cell formed a new skeleton, beginning with the formation of the hypotheca. The different degree of maturation of the skeleton explained the great intraspecific variability in skeletal morphology. These forms share a distinctive crest-like apical structure with several internal radiating slits. These evidences indicate that the genus Monaster corresponds to immature cells with incomplete developed endoskeleton in the epitheca; Amphilothus corresponds to the mature cells with more developed epithecal endoskeleton, while Achradina shows intermediate morphologies and it is the most common form in the plankton samples. The genera Achradina, Amphilothus and Monaster correspond to a single species, with the name Monaster rete having priority.
Підвищення ефективності роботи зерноочисної техніки від шкідливого впливу дисперсного пилу
Authors: Гаек Е.
Published: January 2021

Розглянуто способи підвищення ефективності працездатності зерноочисної техніки в сільськогосподарському виробництві.Метою роботи є підвищення ефективності та працездатності техніки для збирання та обробки зернових культур шляхом комплектування систем очищення: електро-статичним фільтром дизельного палива, використання ротаційного циклону від шкідливого впливу дисперсних частинок.Збільшення довговічності та продуктивності зернозбиральної техніки та зерноочисних машин є однією з найважливіших проблем сучасного розвитку у галузі, тому що простої техніки під час збирання та переробки зернової продукції пов'язано з великими економічними втратами. Технічними аспектами її рішення є поряд з конструкторськими розробками, що забезпечують необхідне підвищення працездатності техніки, поліпшення якості отриманого зернового матеріалу та паливо мастильних матеріалів. Для досягнення поставленої мети пропонуються способів очищення від твердих дисперсних часток. З існуючих засобів очистки, що підвищують працездатність сільськогосподарської зерноочисної техніки, необхідно вибрати оптимальні, що дають при мінімальних витратах максимальний ефект в експлуатаційних умовах сучасного АПВ.У статті представлені способи різного принципу дії з системами доочищення для зерноочисних сепараторів та застосування фільтрів очищення дизельного палива, що використовують неоднорідне електричне поле.За результатами виробничими випробуваннями ротаційного циклону отримано ефективність процесу очищення зернових сумішей від дисперсних частинок пилу на 30…35 %, та збільшення продуктивності пересувних зернових сепараторів на 20…23,2 %. Застосуванням розробленої системи очищення і підготовки дизельного палива показали можливість збільшення ресурсу фільтрів тонкого очищення в 5 разів при одночасному збільшенні ресурсу плунжерних пар ТНВД в 2 рази.
The concept of improving the system of innovation law
Authors: Bryntsev Vasyl
Published: January 2021

Problem setting. The analysis of the state of implementation of innovation law in Ukraine shows the problems caused by the lack of consolidation of the innovation law system at the legislative level, imperfect coordination of efforts of state bodies involved in this area, ineffectiveness of the system of control over law enforcement, and inconsistency in disclosing basic concepts of innovation law. The generalization of the research results testifies to the increased interest in identifying shortcomings and problems of formation and improvement of the innovation law system not only in Ukraine but also among scientists of the Republic of Azerbaijan, the Republic of Belarus, the Republic of Armenia, the Republic of Moldova and other countries.
The purpose of the article. In addition, pay attention to the lack of efficiency of certain provisions of the information base, which is designed to provide an innovative model of economic development of Ukraine.
Presentation of the main research material. Based on a comparative analysis of the basic norms of innovation law of the CIS and Ukraine and the most common positions of Ukrainian scientists on ways to eliminate existing shortcomings, four areas of improving the national legal system in accordance with European standards.
Conclusions and suggestions. In order to give the status of formality and obligation to implement by all law enforcement agencies “recommendations and conclusions” of scientific and practical conferences on innovation, embodied in the Concept of reforming innovation law “with its approval by the Resolution of the Presidium of the Academy of Legal Sciences of Ukraine. authorities and complete the work on the systematization of innovation law of Ukraine by adopting the Innovation Code.
Website WEBSITE APLIKASI ADMISNISTRASI PERIZINAN APOTIK DINAS KESEHATAN BANGKA SELATAN
Authors: Marini Marini
Published: January 2021

Web site aplikasi administrasi perizinan apotik merupakan kegiatan proses bisnis yang dilakukan secara elektronik mengenai dokumentasinya.adapun teknik yang dilakukan dalam untuk melakukan survei informasinya melalui internet secara web page yang dapat digunakan web browser menggunakanPhp Admin..Adapun masalah yang sering terjadi didalam kepengurusan pengajuan administrasi perizinan sering sekali mengalami kendala terutam dalam pengecekan data sering mengalami kesalahan dan pencarian datanya sangat lama.Dengan adanya website aplikasi administrasi perizinan apotik ini maka dalam proses pengajuan, menginput data bisa cepat dilakukan dan mudah. Model pengembangan perangkat lunak menggunakan model FAST yang terdiri dari ruang lingkup, analisis, desain. Metode yang digunakan untuk mengembangkan model perangkat lunak adalah model UML untuk tool pengembagan sistem. Databasenya menggunakan MySql. Dalam implementasi aplikasi administrasi perizinan ini diharapkan supaya dalam pencarian datanya lebih cepat, dalam segi waktu lebih efektif dan efisien serta penyajian laporan nya lebih cepat.
Pengaruh Peran Suami Terhadap Tingkat Kecemasan Ibu Hamil Dalam Menghadapi Proses Persalinan Di Puskesmas Harapan Raya Pekanbaru
Authors: Isnaniar Isnaniar , Norlita Wiwik , Gusrita Salmi
Published: January 2021

Labor is the final process of pregnancy that the mother and family have gone through during three trimester periods. When the labor process begins, the mother's role is to give birth to her baby, while the role of the health worker is to monitor childbirth to detect complications early and with the family to provide assistance and support for maternity mothers. The purpose of this study was to provide an effect on the role of the husband on the level of anxiety of pregnant women in dealing with the delivery process at the Harapan raya puskesmas. The research design used in this study was a quantitative descriptive method, at the Harapan Raya Puskesmas Pekanbaru. The population in this study amounted to 40 pregnant women in Harapan Raya Puskesmas Pekanbaru with a sample size of 33 respondents using the Accidental Sampling method. Data collection techniques using questionnaires and data analysis used were univariate and bivariate. Data collection was obtained using a questionnaire, then analyzed using the chi-square test. The results showed a significant influence between the role of the husband with the anxiety level of pregnant women in dealing with the delivery process with a value of p = 0.001. The conclusion is the influence of the role of the husband on the level of anxiety of pregnant women in dealing with the percentage of labor in the Harapan Raya Health Center Pekanbaru there is an influence between the role of your husband and the level of anxiety of pregnant women.hopefully the third trimester pregnant women can pay moor attention to their condition both phisically phisiologically and ask the husband to always provide suppore and particapate in taking care of the pragnancy as walk as in preparing the pragnancy.
Rencana Pengembangan Jenjang Karir Perawat Klinis Di Rumah Sakit Umum Daerah Kota Dumai
Authors: Efendi Muhammad Rizul , Elfindri  , Yunita Jasrida
Published: January 2021

Professional nurse career development in the form of career paths is a system to improve performance and professionalism, in accordance with the field of work through enhancing competencies that produce professional performance. The aim of this research was to find out the development plan for clinical nurse careers at Dumai Regional General Hospital. The research used is qualitative method. This research was conducted in August 2018. Data analysis was carried out in the form of data appearance, data verification, and matrix formation. The informants in this study amounted to 16 people who were taken based on purposive sampling.The research results obtained important themes namely; Human Resources (HR), Costs and Internship Processes are still a problem in efforts to develop clinical nurse careers. The research results obtained important themes namely; the comparison of the number of clinical assessors and nurses is not ideal, there are regulations about the number of clinical nurses who can participate in the credential process, many clinical nurses who work not according to their competence due to the impact of the length of credential process waiting time, lack of motivation of clinical nurses in following the credential process, not yet the issuance of the prescription decree, the absence of incentives for the preceptor, the lack of formulation of an increase in career level services, and the Internship process not yet implemented in the credential process.  

Keyword- Career, Clinical Nurse
Penentuan Senyawa Dan Pemodelan Suhu Pada Saat Pemanasan Batu Kapur Untuk Mendapatkan CaO Murni Dari Batu Kapur Papua
Authors: Sinaga Egosrivajawaty , Ngaderman Hubertus
Published: January 2021

ABSTRACT

Determination of compounds and temperature modeling during heating of limestone have been carried out to obtain pure CaO from Papua limestone. . The purpose of this research is to determine the compounds, morphology and characteristics of each element and molecule present in limestone from Papua and to simply model the optimum temperature to obtain CaO. From the results of XRF testing, there is one main element that contains the most chemical elements in the limestone sample from black soil (sample 1) and perumnas three (sample 2), namely Ca (calcium) with weight percent 99.57 and 99.69. XRD results are also supported from characterization with EDS where the dominant elements of sample 1 are O, Ca and Mg in sample 2 dominant elements Ca, O and C. Then based on SEM analysis, the morphology of CaMg (CO3) 2, Ca (Co3) and MgCa ( Co3) resembles a cube but the particle size is uneven and irregular due to impurities. The temperature obtained based on the results of this calculation is 12800C.
Setting Strategic Priorities of Floss Marketing Mix in SME “Raja Abon Makmur Lestari”, Pangkalpinang
Authors: Yulia Yulia , Bahtera Novyandra Ilham , Purwasih Rati
Published: January 2021

Raja Abon Makmur Lestari (RAML) is a home industry that produces a various types of flosses both from animal and vegetable. In terms of marketing, the owner faces obstacle such as the fluctuated sales, lack of manpower, unachieved targeted turnover, as well as the high competitiveness in the industry. Thus, the marketing strategic is required to solve the issue. Marketing mix is one of the ways as the marketing strategic to create purchasing decision on the consumers. Case study was used as the approach of the study. The owner and the consumer were the respondent of the study. Quantitative strategic planning matrix (QSPM) was used as a data analysis method. It was used to determine marketing strategic priority based on the internal decision. The descriptive analysis was also used to evaluate the marketing mix. The study found that the marketing mix priority was put in order: promotion, product, place, and price. Furthermore, the priority of sub promotion mix was direct marketing, public relation, mass media and social media. The study was beneficial for the RAML to determine future marketing strategic so that the goals setting will be achieved effectively and efficiently.
Investigation of bending of an elastically supported beam taking into account the inhomogeneity of the base
Authors: Минаева Надежда Витальевна , Сабынин Денис Викторович , Шашкин Александр Иванович
Published: January 2021

Рассмотрен изгиб шарнирно закрепленной балки на упругом основании. Начальный прогиб и неоднородность жесткости основания заданы с точность до малых параметров. Получено условие, определяющее границу области сходимости метода малого параметра. Найдена функция, характеризующая прогиб, с точностью до величин четвертого порядка малости. Проанализирован случай, когда малые параметры являются случайными величинами.

The bending of a pivotally fixed beam on an elastic base is considered. The initial deflection and inhomogeneity of the base stiffness are set up to small parameters. A condition is obtained that defines the boundary of the convergence region of the small parameter method. A function describing the deflection is found up to the fourth order of smallness. The case when small parameters are random variables is analyzed.
5.6. OPTIMIZATION OF THE EXPENDITURE PART OF THE BUDGET OF PROFESSIONAL CLUBS AS A MECHANISM FOR INCREASING THE PROFITABILITY OF THE SPORTS INDUSTRY
Authors: Литвишко О.В. , Губарев Р.В.
Published: January 2021

Заработная плата, выплачиваемая субъектами футбольной индустрии своим работникам, поглощает очень большую долю их доходов, что оказывает существенное воздействие на итоговый финансовый результат клубов. Таким образом, контроль заработной платы является ключом к устойчивому финансовому здоровью клубов. В данной статье рассмотрены основные тенденции в области зарплат в отечественной футбольной отрасли в сравнении с европейскими лигами, выявлены отклонения данного показателя от среднерыночных и рекомендуемых значений, определен алгоритм оптимизации данного показателя. Управление затратами спортивного клуба на основе операционного анализа позволит повысить финансовые показатели и улучшить положение в отрасли за счет снижения издержек и увеличения рентабельности производимого продукта (спортивного зрелища). Гибкая финансовая политика спортивного клуба, учитывающая влияние различных факторов на итоговый результат, позволит им сэкономить финансовые ресурсы, а также снизить издержки финансирования, тем самым повысив рентабельность и уровень их соответствия критериям Союза европейских футбольных ассоциаций (УЕФА) в части финансовой честной игры.

The wages paid by football industry entities to their employees absorb a very large percentage of their income, which has a significant impact on the final financial result of clubs. Wage control is therefore key to the clubs ' sustainable financial health. This article examines the main trends in the field of salaries in the domestic football industry in comparison with European leagues, identifies deviations of this indicator from the average market and recommended values, and defines an algorithm for optimizing this indicator. Cost management of a sports club based on operational analysis will improve financial performance and improve the position in the industry by reducing costs and increasing the profitability of the product (sports spectacle). A flexible financial policy of a sports club that takes into account the impact of various factors on the final result will allow them to save financial resources, as well as reduce financing costs, thereby increasing their profitability and their level of compliance with the UEFA criteria for financial fair play.
8.6. THE SCIENTIFIC RELEVANCE OF REGIONAL COOPERATION IN RUSSIA IN PARADIPLOMACY
Authors: Островская Н.В. , Бурова А.Ю.
Published: January 2021

Наиболее распространенной формой межрегионального трансграничного участия стран в мировой экономике является парадипломатия, сочетающая в себе использование инструментов мягкой и жесткой силы. Проектное управление в региональных органах власти способствует эффективному использованию парадипломатии в регионах Российской Федерации.

The most common form of inter-regional cross-border participation of the countries of the world is para-diplomacy, which combines the use of tools of “soft” and “hard” power. Project management in the regional authorities contributes to the effective use of para-diplomacy in the regions of Russia.
2.1. Reforming the Chinese accounting system in the context of the country's economic development: 40 years of scientific discourse
Authors: Амурская М.А.
Published: January 2021

Данное теоретическое исследование представляет особую научную значимость для российской экономической мысли и направлено на анализ научно-практической литературы Китайской Народной Республики, который сопровождал и оказывал влияние на процессы реформирования китайской учетной системы согласно новым экономическим преобразованиям, которые происходят в стране с 1978 г. Анализ теоретического дискурса представлен в виде двух этапов. Первый этап (1979-1999) представлен в основном теоретическими изысканиями китайских исследователей о природе и функциях новой системы национального бухгалтерского учета и аудита в целом и различных его отраслей, призванных надлежащим образом отражать новые экономические реалии и хозяйственные инструменты. Второй этап (1999 – по настоящее время) связан с активным включением Китая в мировые экономические процессы, в результате которых возникла необходимость перехода национальной системы бухгалтерского учета на международные стандарты

This theoretical research has a particular scientific importance for Russian economic thought and is aimed at analyzing the practical literature of the PRC, which has accompanied and influenced the processes of reforming the Chinese accounting system according to new economic transformations since 1978. The analysis of theoretical discourse is presented in two stages. The first stage (1979–1999) is represented mainly by theoretical research by Chinese researchers about the nature and functions of the new system of national accounting and auditing in general and its various branches, designed to reflect the new economic realities and instruments. The second stage (1999 – present) is associated with the active inclusion of China in the world economic processes, as a result of which was the need for the transition of the national accounting system to international standards (IFRS).
7.5. TRANSFORMATION OF THE COMMUNICATION SYSTEM FOR SMALL BUSINESS PERSONNEL MANAGEMENT IN THE CONTEXT OF DIGITALIZATION OF THE ECONOMY
Authors: Латышев Д.В. , Латышева М.А. , Шохнех А.В.
Published: January 2021

Цифровизация экономики становится ключевым фактором трансформации коммуникативной системы управления персоналом на предприятиях малого бизнеса. Предприниматель вынужден разрабатывать стратегии дальнейшего развития с учетом процесса цифровизации экономики. Создание оптимальной коммуникативной модели позволит обеспечить эффективную работу с внешней и внутренней средой фирмы. На первый план выходят проблемы цифровой стратификации и определения ниши дальнейшего существования бизнеса, оптимальное соотношение затрат и выгод от цифровизации бизнеса, формирование готовности к новому укладу управления, производства и маркетинга.

The digitalization of the economy is becoming a key factor in the transformation of the communication system of personnel management in small businesses. The entrepreneur is forced to develop strategies for further development, taking into account the process of digitalization of the economy. Creation of an optimal communication model will ensure effective work with the external and internal environment of the company. There are the problems coming to the fore: problems of digital stratification and determining a niche for the further existence of a business, the optimal ratio of costs and benefits from business digitalization, formation of readiness for a new structure of management, production and marketing.
7.3. COMPETITIVENESS ESTIMATING OF THE OF RUSSIAN HELICOPTER INDUSTRY
Authors: Карпов А.Е. , Клочков В.В.
Published: January 2021

В статье на примере вертолетостроения рассматривается ключевая проблема стратегического планирования развития наукоемких отраслей промышленности – проблема объективного формирования требований рынка к перспективной продукции. На основе упрощенной экономико-математичес­кой модели прорывного преимущества изделий строятся формальные критерии конкурентоспособности и определяются требования к технико-экономическим характеристикам продукции отечественного производства на рынках вертолетной техники относительно ведущих зарубежных аналогов.

The article considers the key problem of strategic planning for the knowledge-intensive industries development – the problem of objective market requirements for perspective products evaluation, using the example of helicopter industry. Using a simplified economic-mathematical model of breakthrough products advantage, formal competitiveness criteria are built and the requirements in helicopter markets for characteristics of Russian products relative to the leading foreign products are determined.
EXPLORING CREATIVITY THROUGH ARTISTS’ REFLECTIONS
Authors: Daniel Ryan
Published: January 2021

The concept of creativity has been theorized and debated for millennia, dating back to the Greek
philosopher Plato, who referred to “divine madness” in poets. Debates continue as to whether creativity is a gift or talent,
a product of the genius gene, a side effect of mental health conditions, or if it is learned and nurtured through the
environments and societies in which an individual grows and develops. While there is a wealth of research that sets out
to define the concept of creativity, and numerous theoretical models have emerged since the early part of the 20th century,
little of that involves artists reflecting on the concept. In order to explore this area, this study surveyed 314 artists
from a range of countries, using an online survey, which invited them to reflect on creativity as a concept and how they
understand it within their artistic practice. The findings reveal that creativity is a complex term and there is a range of
understandings demonstrated by those who practice art-making. Questions for key stakeholders in education and policy are also
raised, in terms of the role and place of artistic creativity in society.
Start-up of a Research Project on Activities of Solar-type Stars Based on the LAMOST Sky Survey
Authors: He Han , Zhang Haotong , Wang Song , Yang Shuhong , Zhang Jun
Published: January 2021

A research project on the activities of solar-type stars based on the LAMOST sky survey was initiated recently. We describe the data processing workflow of the project and perspective on scientific yields.
Three new species of the segmented spider genus Qiongthela (Mesothelae, Liphistiidae) from Hainan Island, China
Authors: Yu Li , Liu Fengxiang , Zhang Zengtao , Li Daiqin , Xu Xin
Published: January 2021

We report three new species of the segmented trapdoor spider genus Qiongthela Xu & Kuntner, 2015 collected from Hainan Island, China based on morphological characters: Q. dongfangsp. nov. (♂♀), Q. nankaisp. nov. (♂♀), Q. yalinsp. nov. (♂♀). We also provide the GenBank accession codes of the DNA barcode gene, cytochrome c oxidase subunit I (COI), of the type specimens of all three new species to aid future identification.
Narrative Advertising in Destination Branding
Authors: Oralkan Ayca
Published: January 2021

Due to its potential economic return, tourism-related initiatives, including governments, are increasingly focusing on the tourism destination market. It is critical to use efficient marketing methods to enhance travel motivation—especially under the global crises like a pandemic—by encouraging positive consumer impressions of tourism destinations. The main purpose of tourism marketing is to develop a destination image that can enable a sustainable demand for visits through interaction with consumer expectations. One of the most effective marketing methods is to compile stories, which have become a traditional method throughout human history. Narratives use stories to convey various options on behalf of the destination experience in order to build an optimum perception of persuasion. Any destination can have a unique historical culture and original characteristics to be the source materials for effective narrative advertising. These stories should trigger their intention to visit by attracting the attention of potential tourists, and even convince them to visit these destinations.
Corporate Social Responsibility and COVID-19 Pandemic Crisis
Authors: Gigauri Iza
Published: January 2021

The paper aims to clarify the implications of COVID-19 on corporate social responsibility (CSR). The research outlines an important role of CSR during the crisis and examines the pandemic impact on CSR practice of a company. The paper attempts to address the gap in the literature by considering CSR as a response strategy to uncertainties, pandemics, and crises. The study proposes how to adapt to the new normal applying CSR and examines the role of CSR in navigating through ambiguities. The paper analyzes the response to the pandemic crisis in terms of CSR and investigates the CSR approach of companies in Georgia. A semi-structured interview method was applied to collect primary data from companies implementing CSR activities. The novelty of the research results highlights the significance of strategic CSR practice during the pandemic to overcome challenges countries and societies are facing around the world. It contributes to the field of CSR management in times of pandemic and suggests future studies in this area.
Strategies for the Knowledge Management in Value Co-Creation of Industrial Services
Authors: Bonamigo Andrei , Frech Camila Guimarães , Corrêa Nathalia
Published: January 2021

During the value co-creation process, organizations share several resources with their partners, including knowledge. This intangible resource is essential for innovations development, which ensures companies' competitiveness. However, the knowledge transfer across organizational boundaries exposes companies to some risks. Thus, this study aims to examine which KM strategies for value co-creation in industrial services have been presented in the literature. To achieve this goal, first, the authors carried out a systematic literature review (SRL). Then, the resulting portfolio was analyzed following the content analysis proposed by Bardin. From this analysis, it was feasible to identify four KM strategies for value co-creation in industrial services. Among them, adoption of information systems showed a higher frequency. Based on these study findings, it is possible to broaden the knowledge of factors that influence KM in value co-creation and offer advice to managers on how to manage the knowledge shared among firms that jointly create value.
Effect of Pulse Current Electrodeposition on Structural, Mechanical and Corrosion Resistance Properties of Ni- TiO2 Nanocomposite Coatings
Authors: Siad Shahnaz , Marmi Saida , Chala Abdelouahad , Mekkaoui Ameur
Published: January 2021

Ni-TiO2 nanocomposite coatings were fabricated on mild steel surface by pulsed direct current (PC) electrodeposition. This process was carried out in pulsed current at (1, 10, 50) Hz and a duty cycle (25%, 50%, 75%) respectively, at a minimum current density of 0 & high current density of 4 A/dm2. In this work the properties of nanocomposite films were investigated using scanning electron microscopy (SEM), Vickers microhardness measurements and Tafel polarization tests. The composition of the electrodeposits was analyzed by energy dispersive X-ray analysis (EDX). It was found that the coated surface contained at maximum 16.30 % Ti and 35.48 % O. XRD studies revealed [111] preferred orientation. Hardness increased from 560.4 Hv for Ni-TiO2 (F=10 Hz, DC=75 %) nanocomposite coating to 645.7 Hv for Ni-TiO2 (F=10 Hz, DC=25 %) nanocomposite coating. The corrosion resistance of Ni-TiO2 coatings was evaluated by potentiodynamic polarization studies in 3.5 % NaCl solutions. The Pulsed current offer composite coatings with uniform surface, high microhardness and enhanced corrosion resistance significantly for F=10Hz and DC=25 %.
Long-Term Influence of Concussion on Cardio-Autonomic Function in Adolescent Hockey Players
Authors: Memmini Allyssa K. , La Fountaine Michael F. , Broglio Steven P. , Moore Robert D.
Published: January 2021

Context

Concussion may negatively influence cardiovascular function and the autonomic nervous system, defined by alteration in heart rate variability (HRV). Differences in HRV most commonly emerge during a physical challenge, such as the final steps of the return-to-sport progression.

Objective

To assess the effect of concussion history on aspects of cardio-autonomic function during recovery from a bout of submaximal exercise in adolescent male hockey athletes.

Design

Case-control study.

Setting

Research laboratory.

Patients or Other Participants

Thirty-three male athletes participating in Midget-AAA hockey were divided into those with (n = 15; age = 16 ± 1 years, height = 1.78 ± 0.06 m, mass = 73.9 ± 7.4 kg, 10.5 ± 1.6 years of sport experience, 25.2 ± 18.3 months since last injury) or without (n = 18; age = 16 ± 1 years, height = 1.78 ± 0.05 m, mass = 74.8 ± 7.6 kg, 10.6 ± 1.9 years of sport experience) a concussion history. Those with a concussion history were binned on total count: 1 concussion or 2 or more concussions.

Intervention(s)

All athletes underwent 5 minutes of resting HRV assessment, followed by 20 minutes of aerobic exercise at 60% to 70% of their maximal target heart rate and a 9-minute, postexercise HRV assessment.

Main Outcome Measure(s)

Heart rate variability measures of mean NN interval, root mean square of successive differences, and standard deviation of NN interval (SDNN).

Results

Group demographic characteristics were not different. When the control and concussed groups were compared, group and time main effects for heart rate recovery, root mean square of successive differences, and SDNN (P values < .01), and an interaction effect for SDNN (P < .05) were demonstrated. Recovery trends for each group indicated that a history of 2 or more concussions may negatively affect cardio-autonomic recovery postexercise.

Conclusions

Our findings suggest that those with more than 1 previous concussion may be associated with a greater risk for long-term dysautonomia. Future use of HRV may provide clinicians with objective guidelines for concussion-management and safe return-to-participation protocols.
A Predictive Model Based on Bi-parametric Magnetic Resonance Imaging and Clinical Parameters for Clinically Significant Prostate Cancer in the Korean Population
Authors: Noh Tae Il , Hyun Chang Wan , Kang Ha Eun , Jin Hyun Jung , Tae Jong Hyun , Shim Ji Sung , Kang Sung Gu , Sung Deuk Jae , Cheon Jun , Lee Jeong Gu , Kang Seok Ho
Published: January 2021

Purpose This study aimed to develop and validate a predictive model for the assessment of clinically significant prostate cancer (csPCa) in men, prior to prostate biopsies, based on bi-parametric magnetic resonance imaging (bpMRI) and clinical parameters.Materials and Methods We retrospectively analyzed 300 men with clinical suspicion of prostate cancer (prostate-specific antigen [PSA] ≥ 4.0 ng/mL and/or abnormal findings in a digital rectal examination), who underwent bpMRI-ultrasound fusion transperineal targeted and systematic biopsies in the same session, at a Korean university hospital. Predictive models, based on Prostate Imaging Reporting and Data Systems scores of bpMRI and clinical parameters, were developed to detect csPCa (intermediate/high grade [Gleason score ≥ 3+4]) and compared by analyzing the areas under the curves and decision curves.Results A predictive model defined by the combination of bpMRI and clinical parameters (age, PSA density) showed high discriminatory power (area under the curve, 0.861) and resulted in a significant net benefit on decision curve analysis. Applying a probability threshold of 7.5%, 21.6% of men could avoid unnecessary prostate biopsy, while only 1.0% of significant prostate cancers were missed.Conclusion This predictive model provided a reliable and measurable means of risk stratification of csPCa, with high discriminatory power and great net benefit. It could be a useful tool for clinical decision-making prior to prostate biopsies.
Effectiveness and Safety of Clofarabine Monotherapy or Combination Treatment in Relapsed/Refractory Childhood Acute Lymphoblastic Leukemia: A Pragmatic, Non-interventional Study in Korea
Authors: Choi Jung Yoon , Hong Che Ry , Hong Kyung Taek , Kang Hyoung Jin , Kim Seongkoo , Lee Jae Wook , Jang Pil Sang , Chung Nack-Gyun , Cho Bin , Kim Hyery , Koh Kyung-Nam , Im Ho Joon , Seo Jong Jin , Hahn Seung Min , Han Jung Woo , Lyu Chuhl Joo , Yang Eu Jeen , Lim Young Tak , Yoo Keon Hee , Koo Hong Hoe , Kook Hoon , Jeon In Sang , Cho Hana , Shin Hee Young
Published: January 2021

Purpose Effectiveness and safety of clofarabine (one of the treatment mainstays in pediatric patients with relapsed/refractory acute lymphoblastic leukemia [ALL]) was assessed in Korean pediatric patients with ALL to facilitate conditional coverage with evidence development.Materials and Methods In this multicenter, prospective, observational study, patients receiving clofarabine as mono/combination therapy were followed up every 4-6 weeks for 6 months or until hematopoietic stem cell transplantation (HSCT). Response rates, survival outcomes, and adverse events were assessed.Results Sixty patients (2-26 years old; 65% B-cell ALL, received prior ≥ 2 regimen, 68.3% refractory to previous regimen) were enrolled and treated with at least one dose of clofarabine; of whom 26 (43.3%) completed 6 months of follow-up after the last dose of clofarabine. Fifty-eight patients (96.7%) received clofarabine combination therapy. Overall remission rate (complete remission [CR] or CR without platelet recovery [CRp]) was 45.0% (27/60; 95% confidence interval [CI], 32.4 to 57.6) and the overall response rate (CR, CRp, or partial remission [PR]) was 46.7% (28/60; 95% CI, 34.0 to 59.3), with 11 (18.3%), 16 (26.7%), and one (1.7%) patients achieving CR, CRp, and PR, respectively. The median time to remission was 5.1 weeks (95% CI, 4.7 to 6.1). Median duration of remission was 16.6 weeks (range, 2.0 to 167.6 weeks). Sixteen patients (26.7%) proceeded to HSCT. There were 24 deaths; 14 due to treatment-emergent adverse events.Conclusion Remission with clofarabine was observed in approximately half of the study patients who had overall expected safety profile; however, there was no favorable long-term survival outcome in this study.
Correlation of NUF2 Overexpression with Poorer Patient Survival in Multiple Cancers
Authors: Jiang Xiaodan , Jiang Yan , Luo Senbiao , Sekar Karthik , Koh Clara Kai Ting , Deivasigamani Amudha , Dong Qingzhe , Zhang Niankai , Li Shenling , Hao Fengyun , Goh Brian Kim Poh , Ooi London Lucien , Wang Yu , Hui Kam Man
Published: January 2021

Purpose NUF2 has been implicated in multiple cancers recently, suggesting NUF2 may play a role in the common tumorigenesis process. In this study, we aim to perform comprehensive meta-analysis of NUF2 expression in the cancer types included in the Cancer Genome Atlas (TCGA).Materials and Methods RNA-sequencing data in 31 cancer types in the TCGA data and 11 independent datasets were used to examine NUF2 expression. Silencing NUF2 using targeting shRNAs in hepatocellular carcinoma (HCC) cell lines was used to evaluate NUF2’s role in HCC in vitro and in vivo.Results NUF2 up-regulation is significantly observed in 23 out of the 31 cancer types in the TCGA datasets and validated in 13 major cancer types using 11 independent datasets. NUF2 overexpression was clinically important as high NUF2 was significantly associated with tumor stages in eight different cancers. High NUF2 was also associated with significantly poorer patient overall survival and disease-free survival in eight and six cancers, respectively. We proceeded to validate NUF2 overexpression and its negative association with overall survival at the protein level in an independent cohort of 40 HCC patients. Compared to the non-targeting controls, NUF2 knockdown cells showed significantly reduced ability to grow, migrate into a scratch wound and invade the 8 μm porous membrane in vitro. Moreover, NUF2 knockdown cells also formed significantly smaller tumors than control cells in mouse xenograft assays in vivo.Conclusion NUF2 up-regulation is a common feature of many cancers. The prognostic potential and functional impact of NUF2 up-regulation warrant further studies.
Use of valproate in pregnancy and in women of childbearing age between 2014 and 2018 in Switzerland: a retrospective analysis of Swiss healthcare claims data
Authors: Spoendlin Julia , Blozik Eva , Graber Sereina M. , Rauch Marlene , Marxer Carole A. , Rüegg Stephan , Meier Christoph , Winterfeld Ursula , Panchaud Alice
Published: January 2021

AIMS OF THE STUDY
The prevalence of the use of valproate during pregnancy and by women of childbearing age in Switzerland is not known. We aimed to study the use of antiseizure drugs by these women in Switzerland, with a particular focus on valproate.

METHODS
We conducted a retrospective descriptive study using the healthcare claims database of the Swiss health insurance Helsana (2014–18). We established two separate study populations: (1) a cohort of pregnancies leading to a delivery, and (2) all women of childbearing age (15–45 years) who were insured with Helsana for at least one year during the study period. We identified the dispensation of valproate, lamotrigine, carbamazepine, levetiracetam, topiramate, pregabalin, gabapentin, phenobarbital, and phenytoin (1) between delivery and three months prior to the estimated date of the last menstrual period, and (2) by calendar year. We quantified exposure prevalence of each antiseizure drug as the number of women with ≥1 prescription fill per 10,000 (1) pregnancies, and (2) women by calendar year. Results were weighted for the demographic distribution of the Helsana population relative to the Swiss population.

RESULTS
We identified a weighted pregnancy population of 387,418 pregnancies, with a mean maternal age at delivery of 31.9 years (standard deviation 5.1). Lamotrigine was the most frequently dispensed antiseizure drug during pregnancy (20/10,000), followed by levetiracetam (11/10,000), and pregabalin (3.8/10,000). Valproate was dispensed to 1.9/10,000 women during pregnancy and to 1.3/10,000 women within 90 days prior to the last menstrual period but not during pregnancy. The weighted study population of women aged 15–45 years consisted of 2,781,151 women, of whom 74,080 (270/10,000) were exposed to ≥1 of the evaluated antiseizure drugs. Pregabalin was the most frequently dispensed antiseizure drug (64/10,000), followed by lamotrigine (46/10,000), topiramate (32/10,000), and valproate (25/10,000). The use of valproate decreased from 28/10,000 women in 2014 to 21/10,000 women in 2018.

CONCLUSIONS
The prevalence of exposure to valproate during pregnancy was comparable to Denmark and lower than in other European countries. Despite decreasing exposure prevalence, the use of valproate in women of childbearing age in Switzerland seems higher than the actual clinical need.
An Intelligent Tire Pressure Monitoring System
Authors: S Kirubakaran , C Kamalanathan , Ponnuswamy Dinesh
Published: January 2021

Pressure of tire is measured using Tire Pressure Monitoring System (TPMS) model. By measuring the tire pressure, the fuel can be saved and the vehicle can be controlled in better way. The real of tire pressure can be monitored in real time and if the pressure of the tire goes out of the threshold this system gives alarm and alert the driver to ensure the driver safety, hence the life of the driver can be safeguard and pre-warn the driver and passengers. TPMS consists of an electronic unit that sense the tire pressure displays it to user in a LABVIEW platform. This unit includes a pressure sensor and Data Acquisition System. The output of the pressure sensor is given to the Data Acquisition System. Then the DAQ is interfaced with PC to display the tire pressure in the dashboard using the LABVIEW platform. If the tire pressure crosses safe pressure level a warning is generated
Hybrid Renewable Resource Power Generation using Back to Back Voltage Source Converter with Output Regulation
Authors: K Prabaakaran , R Senthil Kumar , Katta Pradeep , P R Jain Vinith , S Ashok , M Kathiravan
Published: January 2021

There is a massive and rapid development in the industry and prevailing population inflation due to which the energy demand spikes. The increase in demand dilates the gap between the energy supplied and usage which makes the power quality important to consider, otherwise it causes voltage, current or frequency deviations which has unfavourable consequences in customer’s equipment or result in failure. To overcome this the concept of complementary usage of wind and solar cogeneration system is introduced along with the topology with Neutral Point Clamped inverter which has 3-level output converter that decreases the harmonics and the switching rate, it also features the regulation of the VSC through fuzzy based control scheme in the rotating reference frame of wind-solar cogeneration system with no extra DC/DC conversion stages.
Automatic Anaesthesia Regularization System
Authors: R Rajeshwari , K Sumithra , S Kiruthika , M Anusuya
Published: January 2021

Nowadays, in surgeries, the anaesthesia is delivered manually. During this process, there is a chance to commit minute mistakes which may lead to lethal complications. During anaesthesia drug injection, the doctors should concentrate on the drug dosage, amount of drug, response of vital body parameters. The vital body parameters include temperature, blood pressure, heart rate. The incorrect dosage administration may cause lethal effects. To avoid this, the anaesthetist administers few millilitres of anaesthesia in a regular intervals of time to the patient. Thus ,a microcontroller based automatic anaesthesia regularization system is developed. So that the adequate amount of drug is injected in optimum level, which ensures the patient safety. The drug is delivered depending on the sensors output.
Gesture Controlled Wheelchair
Authors: S Patricia Nancy , S Shanchana , A AllwynGnanadas , nila Udhaya
Published: January 2021

Wheelchairs are widely used by people who suffer from a disability, spinal cord injury, accident, or have difficulty in walking. Wheelchairs are of great use now-a-days to aged persons at home, orphanage and hospitals. This paper aims at presenting a wheelchair which can be used without external assistance. The wheelchair can be controlled by using the hand gestures of the user themselves. The hand gestures are being sensed with the help of the 3-axis accelerometer sensor. The output of this MEMS sensor is being given to the ATMEGA-328 microcontroller chip.
Property Enhancement of Aluminium Alloy 2000 Series Strengthened by Synthetic, Self-Lubricant and Natural Reinforcements
Authors: V Bhuvaneswari , Devarajan Balaji , L Rajeshkumar
Published: January 2021

Wider usage of aluminium alloy composites can be seen in several sectors like automobile, aerospace and marine application. Current article clearly explains the property enhancement of aluminium alloy composites reinforced with natural materials and is compared with synthetic as well as hybrid reinforcements. AA2219 is taken as a base metal and BC, WC, Al2O3, MOS2, Graphite, Sea shell powder (SSP) are taken as reinforcing agents. Stir casting technique is adopted to fabricate a test specimen since it is flexible and easy to cast among remaining casting methods in metal matrix composite. Above mentioned reinforcements are taken with a weight percentage of 1, 2 and 3. For property enhancement evaluation, hardness test is carried out. It is observed from the evaluation, natural reinforcement result in better enhancement than the synthetic reinforcements.
Modulationof The Recirculation Region Within Two Inline Square Rib Due toMagnetohydrodynamic	FlowUsingComputational Fluid Dynamics
Authors: Roy Sayahnya , N Gunasekaran , Barman Krishnendu , Debnath Koustuv , Sinha Prantik
Published: January 2021

This study presents the turbulent flow around two square ribs. The numerical computations performed using k–ε model at Reynolds number (Re) = 60000 to quantify the turbulent transport measures. The magnetic field has been applied by Hartmann number (Ha) to generate the magnetohydrodynamic (MHD) flow. The reduction of recirculation region was observed due to the application of magnetic field in the flow. The weak recirculation has an effect on small vorticity generation, which leads to small turbulent kinetic energy (TKE) and TKE dissipation rate generation in the wake region behind the rib. The induced magnetic field is capable of controlling the vortex structures around the square ribs. Results in decreasing magnitude of turbulence level around and between the spaces of the square ribs. It may be hypothesized that by introducing magnetic field, the unwanted vibrations (due to vortex shedding behind the rib) of fully submerged structures can be controlled.
Storytelling as a Pedagogical Tool in Teaching English Idioms for Engineering Students to Enhance Proficiency
Authors: B Sinduja , vadhana Mathi
Published: January 2021

Language is a powerful weapon which can make or mar a scenario. To update such a language, we need to enlarge the linguistic skills. Teaching is successful, when the appropriate methodology is chosen according to the concept. This paper caters the best pedagogical tool to learn and teach English idioms for L2 learners of engineering students in an efficient way. Storytelling aids the learners to comprehend and remember the idioms easily. Storytelling method for teaching idioms is suitable from kinder garden children to scholars. Basically, learning idioms is not a piece of cake; this is the tenet of students. This paper will break this myth and make L2 learners of English to love English idiom usage willingly.