bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between Agility, Health-Related Quality of Life, Depression, and Anthropometric Variables in Physically Active Older Adult Women with Depression
Authors: Galán-Arroyo Carmen , Pereira-Payo Damián , Hernández-Mocholí Miguel A. , Merellano-Navarro Eugenio , Pérez-Gómez Jorge , Rojo-Ramos Jorge , Adsuar José Carmelo
Published: January 2022

Introduction. Depressive disorders are mental disorders that last over time, and seriously affect the lives of the people who suffer from them, diminishing their quality of life, reducing their motor capacity, and incapacitating them in their daily lives. It is a major problem worldwide. Objective. To study the association between agility, health-related quality of life (hrqol), anthropometric status, and depression status in older adult women with depression. Design. Data collected from 685 physically active older women with depression were analyzed. Result. A moderate inverse correlation (r = −0.34) is shown between Time Up & Go (TUG) and EuroQol Five-Dimensional Three-Level Version (EQ-5D-3L). Between TUG and Geriatric Depression Scale (GDS), there is a small direct correlation (r = 0.14) between them. Between TUG and anthropometric data, all observed correlations are significant. Conclusions. There is a significant association between agility, health-related quality of life, depression, and anthropometric data in physically active older women with depression.
The Mediating Role of Vision in the Relationship between Proprioception and Postural Control in Older Adults, as Compared to Teenagers and Younger and Middle-Aged Adults
Authors: Nieto-Guisado Ainhoa , Solana-Tramunt Monica , Marco-Ahulló Adrià , Sevilla-Sánchez Marta , Cabrejas Cristina , Campos-Rius Josep , Morales Jose
Published: January 2022

The aim of this study is to analyze the mediating role of vision in the relationship between conscious lower limb proprioception (dominant knee) and bipedal postural control (with eyes open and closed) in older adults, as compared with teenagers, younger adults and middle-aged adults. Methods: The sample consisted of 119 healthy, physically active participants. Postural control was assessed using the bipedal Romberg test with participants’ eyes open and closed on a force platform. Proprioception was measured through the ability to reposition the knee at 45°, measured with the Goniometer Pro application’s goniometer. Results: The results showed an indirect relationship between proprioception and postural control with closed eyes in all age groups; however, vision did not mediate this relationship. Conclusions: Older adults outperformed only teenagers on the balance test. The group of older adults was the only one that did not display differences with regard to certain variables when the test was done with open or closed eyes. It seems that age does not influence performance on proprioception tests. These findings help us to optimize the design of training programs for older adults and suggest that physical exercise is a protective factor against age-related decline.
The First 1000 Days of Infant
Authors: Brines Juan , Rigourd Virginie , Billeaud Claude
Published: January 2022

The third edition of the Nursing and Pediatrics Congress was held in Paris from 16–19 June 2021, with the aim of contributing the experiences and reflections of relevant health professionals (pediatricians, pediatric surgeons, obstetricians, nurses, midwives, dieticians, and lactation consultants) to the knowledge of the most critical period of human life: its first 1000 days [...]
Low CO2 Levels Are Detrimental for In Vitro Plantlets through Disturbance of Photosynthetic Functionality and Accumulation of Reactive Oxygen Species
Authors: Askari Naser , Aliniaeifard Sasan , Visser Richard G. F.
Published: January 2022

Photosynthesis of plantlets in tissue culture containers is not considered important, compared to photosynthesis of ex vitro plants, due to the exogenous source of carbohydrates present in tissue culture media. However, CO2 starvation can generate a burst of reactive oxygen species (ROS). We examined this phenomenon in tissue culture, since CO2 levels may become very low during the light period. The research was carried out with lily scales, regenerating adventitious bulblets, and with Arabidopsis seedlings. CO2 starvation was achieved by placing a small vial of concentrated KOH solution in the culture container. CO2 removal reduced the growth of regenerated lily bulblets by 33% or 23%, with or without sucrose in the medium, respectively. In Arabidopsis seedlings, CO2 removal decreased growth by 50% or 78% in the presence or absence of sucrose in the medium, respectively. Therefore, the addition of sucrose as a replacement for photosynthesis resulted in only partial recovery of growth. Staining with nitroblue tetrazolium (NBT) showed little to no ROS in ex vitro growing seedlings, while abundant ROS were detected in seedlings grown under in vitro CO2 starvation. Seedlings grown under normal tissue culture conditions (no CO2 withdrawal) showed low levels of ROS. In lily tissue culture, CO2 starvation decreased the maximum quantum efficiency of photosystem II (Fv/Fm) from 0.69 to 0.60, and in Arabidopsis from 0.76 to 0.62. Fv/Fm of ex vitro lily and Arabidopsis seedlings was 0.77 and 0.79, respectively. This is indicative of a disturbance in photosynthesis functionality and the occurrence of in vitro stress under reduced CO2 concentrations. We conclude that poor growth, in the absence of CO2, was partly due to strongly reduced photosynthesis, while the detrimental effects were most likely due to a burst of ROS.
Mitigation of Commercial Food Waste-Related Salinity Stress Using Halotolerant Rhizobacteria in Chinese Cabbage Plants
Authors: Khan Muhammad Aaqil , Kalsoom  , Imran Muhammad , Lubna  , Shaffique Shifa , Kwon Eun-Hae , Kang Sang-Mo , Kim Seong-Heon , Hamayun Muhammad , Lee In-Jung
Published: January 2022

The use of commercial food waste in the Korean agricultural industry is increasing due to its capacity to act as an ecofriendly fertilizer. However, the high salt content of food waste can be detrimental to plant health and increase salinity levels in agricultural fields. In the current study, we introduced halotolerant rhizobacteria to neutralize the negative impact of food waste-related salt stress on crop productivity. We isolated halotolerant rhizobacteria from plants at Pohang beach, and screened bacterial isolates for their plant growth-promoting traits and salt stress-mitigating capacity; consequently, the bacterial isolate Bacillus pumilus MAK9 was selected for further investigation. This isolate showed higher salt stress tolerance and produced indole-3-acetic acid along with other organic acids. Furthermore, the inoculation of B. pumilus MAK9 into Chinese cabbage plants alleviated the effects of salt stress and enhanced plant growth parameters, i.e., it increased shoot length (32%), root length (41%), fresh weight (18%), dry weight (35%), and chlorophyll content (13%) compared with such measurements in plants treated with food waste only (control). Moreover, relative to control plants, inoculated plants showed significantly decreased abscisic acid content (2-fold) and increased salicylic acid content (11.70%). Bacillus pumilus MAK9-inoculated Chinese cabbage plants also showed a significant decrease in glutathione (11%), polyphenol oxidase (17%), and superoxide anions (18%), but an increase in catalase (14%), peroxidase (19%), and total protein content (26%) in comparison to the levels in control plants. Inductively coupled plasma mass spectrometry analysis showed that B. pumilus MAK9-inoculated plants had higher calcium (3%), potassium (22%), and phosphorus (15%) levels, whereas sodium content (7%) declined compared with that in control plants. Similarly, increases in glucose (17%), fructose (11%), and sucrose (14%) contents were recorded in B. pumilus MAK9-inoculated plants relative to in control plants. The bacterial isolate MAK9 was confirmed as B. pumilus using 16S rRNA and phylogenetic analysis. In conclusion, the use of commercially powered food waste could be a climate-friendly agricultural practice when rhizobacteria that enhance tolerance to salinity stress are also added to plants.
Pneumonic Plague: Incidence, Transmissibility and Future Risks
Authors: Evans Charles
Published: January 2022

Pneumonic plague outbreaks are relatively infrequent in modern times, but in the early part of the 20th century, they were commonplace including several well-documented epidemics responsible for the deaths of thousands. The transmissibility of this disease seems to be discontinuous since in some outbreaks few transmissions occur, while in others, the progression of the epidemic is explosive. Modern epidemiological studies explain that transmissibility within populations is heterogenous with relatively few subjects likely to be responsible for most transmissions and that ‘super spreading events’, particularly at the start of an outbreak, can lead to a rapid expansion of cases. These findings concur with outbreaks observed in real-world situations. It is often reported that pneumonic plague is rare and not easily transmitted but this view could lead to unnecessary complacency since future risks such as the spontaneous incidence of anti-microbial strains, climate change leading to a disruption of natural cycles within plague foci and use of plague as a bioweapon cannot be discounted. Carers and first responders are vulnerable, particularly in poorer countries where access to medicines and protection equipment may be limited, outbreaks occur in inaccessible areas or where there is a lack of surveillance due to a paucity of funds.
The Combination of Bacillus Thuringiensis and Its Engineered Strain Expressing dsRNA Increases the Toxicity against Plutella Xylostella
Authors: Jiang Ying-Xia , Chen Jin-Zhi , Li Miao-Wen , Zha Ben-Hu , Huang Peng-Rong , Chu Xue-Mei , Chen Jing , Yang Guang
Published: January 2022

RNA interference (RNAi) has been developed and used as an emerging strategy for pest management. Here, an entomopathogen Bacillus thuringiensis (Bt) was used to express the dsRNA for the control of Plutella xylostella. A vector containing a 325-bp fragment of the conserved region of P. xylostella arginine kinase gene (PxAK) flanking in two ends with the promoter Pro3α was developed and transferred into Bt 8010 and BMB171, and consequently engineered Bt strains 8010AKi and BMB171AKi expressing dsRNA of PxAK were developed. The two engineered Bt strains were separately mixed with Bt 8010 in a series of ratios, and then fed to the P. xylostella larvae. We found that 8010:8010AKi of 9:1 and 8010:BMB171AKi of 7:3 caused a higher mortality than Bt 8010. PxAK expression levels in the individuals treated with the mixtures, 8010AKi and BMB171Aki, were lower than that in the control. The intrinsic rate of increase (r) and net reproductive rate (R0) of the population treated with 8010:8010AKi of 9:1 were lower than those of the population treated with Bt 8010 or 8010AKi. We developed a Bt-mediated insect RNAi for the control of P. xylostella and demonstrated a practical approach to integrating the entomopathogen with RNAi technique for the pest management.
Microvascular Experimentation in the Chick Chorioallantoic Membrane as a Model for Screening Angiogenic Agents including from Gene-Modified Cells
Authors: Kennedy Donna C. , Coen Barbara , Wheatley Antony M. , McCullagh Karl J. A.
Published: January 2022

The chick chorioallantoic membrane (CAM) assay model of angiogenesis has been highlighted as a relatively quick, low cost and effective model for the study of pro-angiogenic and anti-angiogenic factors. The chick CAM is a highly vascularised extraembryonic membrane which functions for gas exchange, nutrient exchange and waste removal for the growing chick embryo. It is beneficial as it can function as a treatment screening tool, which bridges the gap between cell based in vitro studies and in vivo animal experimentation. In this review, we explore the benefits and drawbacks of the CAM assay to study microcirculation, by the investigation of each distinct stage of the CAM assay procedure, including cultivation techniques, treatment applications and methods of determining an angiogenic response using this assay. We detail the angiogenic effect of treatments, including drugs, metabolites, genes and cells used in conjunction with the CAM assay, while also highlighting the testing of genetically modified cells. We also present a detailed exploration of the advantages and limitations of different CAM analysis techniques, including visual assessment, histological and molecular analysis along with vascular casting methods and live blood flow observations.
Genome-Wide Association Study Identifies Candidate Genes Related to the Linoleic Acid Content in Soybean Seeds
Authors: Di Qin , Piersanti Angela , Zhang Qi , Miceli Cristina , Li Hui , Liu Xiaoyi
Published: January 2022

Soybean (Glycine max (L.) Merrill) oil is a complex mixture of five fatty acids (palmitic, stearic, oleic, linoleic, and linolenic). The high content of linoleic acid (LA) contributes to the oil having poor oxidative stability. Therefore, soybean seed with a lower LA content is desirable. To investigate the genetic architecture of LA, we performed a genome-wide association study (GWAS) using 510 soybean cultivars collected from China. The phenotypic identification results showed that the content of LA varied from 36.22% to 72.18%. The GWAS analysis showed that there were 37 genes related to oleic acid content, with a contribution rate of 7%. The candidate gene Glyma.04G116500.1 (GmWRI14) on chromosome 4 was detected in three consecutive years. The GmWRI14 showed a negative correlation with the LA content and the correlation coefficient was −0.912. To test whether GmWRI14 can lead to a lower LA content in soybean, we introduced GmWRI14 into the soybean genome. Matrix-assisted laser desorption/ionization time-of-flight imaging mass spectrometry (MALDI-TOF IMS) showed that the overexpression of GmWRI14 leads to a lower LA content in soybean seeds. Meanwhile, RNA-seq verified that GmWRI14-overexpressed soybean lines showed a lower accumulation of GmFAD2-1A and GmFAD2-1B than control lines. Our results indicate that the down-regulation of the FAD2 gene triggered by the transcription factor GmWRI14 is the underlying mechanism reducing the LA level of seed. Our results provide novel insights into the genetic architecture of LA and pinpoint potential candidate genes for further in-depth studies.
Studies of the Formation and Stability of Ezetimibe-Cyclodextrin Inclusion Complexes
Authors: Biernacka Marta , Ilyich Tatsiana , Zavodnik Ilya , Pałecz Bartłomiej , Stepniak Artur
Published: January 2022

In the presented studies, the interactions between ezetimibe (EZE) and selected cyclodextrins were investigated. α-Cyclodextrin (αCD), β-cyclodextrin (βCD) and its modified derivatives, hydroxypropyl-β-cyclodextrin (HPβCD) and sulfobutylether-β-cyclodextrin (SBEβCD), were selected for the research. Measurements were carried out using calorimetric and spectroscopic methods. Additionally, the Hirshfeld surface and biochemical analysis were achieved. As a result of the study, the inclusion complexes with 1:1 stoichiometry were obtained. The most stable are the complexes of β-cyclodextrin and its derivatives. The comparison of βCD with its derivatives shows that the modifications have an affect on the formation of more durable and stable complexes.
Dental Mesenchymal Stem Cell Secretome: An Intriguing Approach for Neuroprotection and Neuroregeneration
Authors: Gugliandolo Agnese , Mazzon Emanuela
Published: January 2022

Mesenchymal stem cells (MSCs) are known for their beneficial effects and regenerative potential. In particular, dental-derived MSCs have the advantage of easier accessibility and a non-invasive isolation method. Moreover, thanks to their neural crest origin, dental MSCs seem to have a more prominent neuroregenerative potential. Indeed, in basal conditions they also express neuronal markers. However, it is now well known that the beneficial actions of MSCs depend, at least in part, on their secretome, referring to all the bioactive molecules released in the conditioned medium (CM) or in extracellular vesicles (EVs). In this review we focus on the applications of the secretome derived from dental MSCs for neuroregeneration and neuroprotection. The secretomes of different dental MSCs have been tested for their effects for neuroregenerative purposes, and the secretomes of dental pulp stem cells and stem cells from human exfoliated deciduous teeth are the most studied. Both the CM and EVs obtained from dental MSCs showed that they are able to promote neurite outgrowth and neuroprotective effects. Interestingly, dental-derived MSC secretome showed stronger neuroregenerative and neuroprotective effects compared to that obtained from other MSC sources. For these reasons, the secretome obtained from dental MSCs may represent a promising approach for neuroprotective treatments.
Translational Study of Copy Number Variations in Schizophrenia
Authors: Cheng Min-Chih , Chien Wei-Hsien , Huang Yu-Shu , Fang Ting-Hsuan , Chen Chia-Hsiang
Published: January 2022

Rare copy number variations (CNVs) are part of the genetics of schizophrenia; they are highly heterogeneous and personalized. The CNV Analysis Group of the Psychiatric Genomic Consortium (PGC) conducted a large-scale analysis and discovered that recurrent CNVs at eight genetic loci were pathogenic to schizophrenia, including 1q21.1, 2p16.3 (NRXN1), 3q29, 7q11.23, 15q13.3, distal 16p11.2, proximal 16p11.2, and 22q11.2. We adopted a two-stage strategy to translate this knowledge into clinical psychiatric practice. As a screening test, we first developed a real-time quantitative PCR (RT-qPCR) panel that simultaneously detected these pathogenic CNVs. Then, we tested the utility of this screening panel by investigating a sample of 557 patients with schizophrenia. Chromosomal microarray analysis (CMA) was used to confirm positive cases from the screening test. We detected and confirmed thirteen patients who carried CNVs at these hot loci, including two patients at 1q21.1, one patient at 7q11.2, three patients at 15q13.3, two patients at 16p11.2, and five patients at 22q11.2. The detection rate in this sample was 2.3%, and the concordance rate between the RT-qPCR test panel and CMA was 100%. Our results suggest that a two-stage approach is cost-effective and reliable in achieving etiological diagnosis for some patients with schizophrenia and improving the understanding of schizophrenia genetics.
Vypal2: A Versatile Peptide Ligase for Precision Tailoring of Proteins
Authors: Zhang Dingpeng , Wang Zhen , Hu Side , Lescar Julien , Tam James P. , Liu Chuan-Fa
Published: January 2022

The last two decades have seen an increasing demand for new protein-modification methods from the biotech industry and biomedical research communities. Owing to their mild aqueous reaction conditions, enzymatic methods based on the use of peptide ligases are particularly desirable. In this regard, the recently discovered peptidyl Asx-specific ligases (PALs) have emerged as powerful biotechnological tools in recent years. However, as a new class of peptide ligases, their scope and application remain underexplored. Herein, we report the use of a new PAL, VyPAL2, for a diverse range of protein modifications. We successfully showed that VyPAL2 was an efficient biocatalyst for protein labelling, inter-protein ligation, and protein cyclization. The labelled or cyclized protein ligands remained functionally active in binding to their target receptors. We also demonstrated on-cell labelling of protein ligands pre-bound to cellular receptors and cell-surface engineering via modifying a covalently anchored peptide substrate pre-installed on cell-surface glycans. Together, these examples firmly establish Asx-specific ligases, such as VyPAL2, as the biocatalysts of the future for site-specific protein modification, with a myriad of applications in basic research and drug discovery.
Mengisahkan Ziarah Eksodus Melalui Eskterior Bangunan Gereja
Authors: Rachman Rasid
Published: January 2022

The exterior of Church building is the clearest face of the community of its members because it is openly showed by anybody. It is not only evidence of the very art and historical heritage but also a content of theological narrative and re-narrative of Church role in the world. This writing will show that there is a theological narrative behind the Church building. In this writing, that theological narrative is limited to the story of the journey and the sojourn of the Israel people in the wilderness to the promised land. From the exodus narrative, I renarrate the role of the Church in the context where it lives. This writing used the theory of bottom with three elements, namely: concept, category, and proposition. The early concept is the exodus narrative according to the Bible. Catching the category, this exodus concept will be anriched by the blended with the narrative of some Church buildings in Indonesia, theology of the Old Testament and liturgy, the anthropology of culture, and the philosophy of architecture. The result of this research is renarrative of the living Church buildings. The proposition is an offer on an interrelation between Biblical narrative, a historical roll of the Church building, and the renarrative or the storytelling renewal, with the present of Church mission. Eksterior bangunan gereja adalah wajah paling jelas persekutuan anggotanya, sebab terlihat secara terbuka oleh siapa pun. Ia bukan hanya bukti mahakarya seni arsitektur dan peninggalan sejarah, tetapi juga berisi narasi teologis dan merenarasikan peran gereja di dunia. Tulisan ini ingin memperlihatkan bahwa ada narasi teologi di balik eksterior bangunan gereja. Dalam tulisan ini, narasi teologi tersebut dibatasi pada kisah perjalanan dan persinggahan umat Israel di padang gurun menuju tanah perjanjian. Dari narasi eksodus tersebut, saya merenarasikan peran gereja di dalam konteksnya.Tulisan ini menggunakan teori dari bawah dengan tiga unsur, yaitu: konsep, kategori, dan proposisi. Konsep awal adalah narasi eksodus sebagaimana kesaksian Alkitab. Untuk mencapai kategori, konsep eksodus ini akan diperkaya dengan memadukan narasi beberapa bangunan gereja di Indonesia, teologi Perjanjian Lama dan liturgi, antropologi budaya, dan filsafat arsitektur. Hasil penelitian adalah renarasi bangunan gereja yang hidup. Proposisi berupa tawaran akan hubungan-hubungan antara narasi Alkitab, guliran historis bangunan gereja berdiri, dan renarasi atau pembaruan penceritaan, dengan misi gereja kini.
Continuing the Paul Mission for the Gentiles in the New Era
Authors: Sampe Naomi , Masuang Perdi , Lembang Gantina Banne , Sara Rinus Menok , Toding Karel Sanda
Published: January 2022

The research in this paper seeks to find some thought as a product of research that examines the important role of Paul's mission in the early church planting. In addition, this article will examine the pattern of Paul's mission so that church growth is very sporadic. The purpose of this research is to show that Paul's success strategy in mission is very worthy and interesting to be researched and studied, so that it becomes a cornerstone for the church today to continue Paul's mission pattern. Methodology in this research is going to use the theory of Francis Watson which based on the freedom of Paul mission, and also it want to take advantage based on the theory of Terence L. Donaldson that stated the universalism of Paul mission. This research shows that through God's help, Paul succeeded in establishing Gentiles churches. The churches today may learn that the preaching of the Gospel to the new generation today has its own challenges, because the different context. Another thing that today's church needs to learn is that Paul's passion and strategy in his mission has enabled him to build churches for other nations in various places for the glory of Christ.Penelitian dalam tulisan ini hendak berupaya menemukan beberapa refleksi sebagai hasil riset yang meneliti tentang peran penting misi Paulus terhadap perintisan gereja perdana. Selain itu, risalah ini hendak meneliti bagaimana pola misi Paulus sehingga pertumbuhan gereja sangat sporadis. Tujuan penelitian ini adalah hendak menunjukkan bahwa strategi keberhasilan Paulus dalam misi sangat layak dan menarik untuk diteliti dan dipelajari, agar menjadi batu penjuru bagi gereja masa kini untuk melanjutkan pola misi Paulus. Teologi misi Paulus yang berkaitan dengan pekerjaan misionaris yang dia layani saat itu. Tulisan ini mencoba menggunakan perspektif Francis Watson tentang kebebasan misi rasul Paulus. Selain itu juga didasarkan pada teori Terence L. Donaldson yang menyatakan tentang universalisme dari misi Paulus. Metodologi dalam penelitian ini akan menggunakan teori Francis Watson yang didasarkan pada kebebasan misi Paulus, serta ingin memanfaatkan teori Terence L. Donaldson yang menyatakan universalisme misi Paulus. Penelitian ini memperlihatkan bahwa melalui pertolongan Tuhan, Paulus berhasil mendirikan gereja-gereja non-Yahudi. Manfaat bagi gereja masa kini adalah bahwa Pemberitaan Injil bagi generasi era baru saat ini memiliki tantangan tersendiri karena konteksnya tidak sama lagi dengan era Paulus. Hal lain yang perlu dikaji oleh gereja era masa kini adalah semangat dan strategi Paulus dalam misinya, telah memampukannya membangun gereja-gereja bagi bangsa-bangsa lain untuk kemuliaan Kristus.
Bimbingan Karir Berbasis Konsep Manusia Toraja di Era Revolusi Industri 4.0
Authors: Titting Herman , Feriyanto Feriyanto
Published: January 2022

This research aims to review human concept-based career guidance in the Context of Toraja to help students in the era of the industrial revolution 4.0. The importance of this research is based on the background of the lack of student-oriented career guidance based on human concepts in its culture. The data is obtained using qualitative methods through literature studies, field observations, and interviews. The data was analyzed with a descriptive qualitative approach with steps according to Creswell, so that it found themes of career guidance based on human concepts in a particular culture. This study concludes that career guidance is very appropriate to be based on human concepts, such as the concept of lolo tau in the context of Toraja to prepare students for the industrial revolution 4.0.
Tujuan dari penelitian ini adalah untuk mengkaji bimbingan karir berbasis konsep manusia dalam konteks Toraja untuk membantu siswa di era revolusi industri 4.0. Pentingnya penelitian ini didasarkan pada latarbelakang kurangnya bimbingan karir yang berorientasi pada siswa berdasarkan konsep manusia dalam budayanya. Data diperoleh dengan menggunakan metode kualitatif melalui studi literatur, pengamatan lapangan dan wawancara. Data dianalisis dengan pendekatan kualitatif deskriptif dengan langkah-langkah menurut Creswell, sehingga ditemukan tema-tema bimbingan karir berbasis konsep manusia pada budaya tertentu. Kesimpulan dari penelitian ini adalah bimbingan karir sangatlah tepat untuk dapat didasarkan pada konsep manusia, seperti konsep lolo tau dalam konteks Toraja untuk mempersiapkan siswa menghadapi revolusi industri 4.0.
Dilema Kepemimpinan Kristen, Tuhan atau atasan?
Authors: Sanderan Rannu
Published: January 2022

This paper aims to examine and describe the nature of dedicated Christian leadership and to explore the essential elements of servanthood leadership. To serve is one of the most basic substances of Jesus' work. The problem of Christian leadership today is when leaders lose the character of Christ and are trapped in manipulating the name of Christianity or the church for the sake of his/her power. Methodically, this research refers to the leadership patterns of figures in the Old and New Testaments, with the support of literature studies that discuss Christian leadership discourse.

 Jesus displaying his leadership as a critique towards the misgovern leader who can only tells order, same as the authoritarian leadership, those who reigning over the official or government employee by own wish or merely by his/her desire. If so, it means that the leader's character humiliates even corrupts his/her own leadership. In all conscience, the leader is a minister to his/her follower's needs; to serve with love, humility, and forgiveness. The result of this study emphasizes that Christian leaders who want to grow up should simply be like Jesus, great leaders originally ought to serve others first, thus in plain reality, the core of his/her leadership will be visible in greatness.

 

Tulisan ini hendak mengkaji dan menguraikan hakikat kepemimpinan Kristen yang mengabdi, dan mencari tahu unsur esensial dari kepemimpinan yang mengabdi. Mengabdi/melayani adalah sebuah unsur yang sangat mendasar dalam kepemimpinan Yesus. Problem kepemimpinan Kristen masa kini adalah ketika pemimpin kehilangan karakter Kristus, dan justru terjebak mengatasnamakan kekristenan dan gereja untuk kepentingan kekuasaan. Secara metodik, penelitian ini merujuk pola kepemimpinan tokoh dalam Perjanjian Lama dan Perjanjian Baru, dengan dukungan studi kepustakaan yang membahas wacana kepemimpinan Kristen. Yesus memberikan kritik pada kepemimpinan yang bersifat memerintah pengikut, menempatkan pimpinan sebagai bos yang harus selalu diikuti perkataan dan kehendaknya dan tidak memberikan teladan benar. Karakter pemimpin yang demikian merusak dan merendahkan wibawa eksistensi dari kepemimpinan. Seorang pemimpin adalah pelayan bagi pengikutnya. Melayani dgn kasih dan pengampunan. Hasil pengkajian ini menandaskan bahwa seharusnya pemimpin Kristen yang mau besar, mula-mula harus melayani orang lain, dan bahwa kenyataan yg sederhana ini merupakan inti kebesaran-Nya sebagai seorang pemimpin
Analisis Pengaruh Pendidikan Keluarga dan Lingkungan Sosial Terbentuknya Identitas LGBT
Authors: Barutu Parsaoran , Hendriks Alvyn Cesarianto , Hutagalung Stimson , Ferinia Rolyana
Published: January 2022

Fenomena jumlah LGBT di kota Batam sangat mencengangkan. LGBT adalah sebuah penyimpangan sexual yang dapat merusak generasi remaja dan merusak Gereja sebagai tubuh Kristus. Perlu pencegahan yang serius secara terpadu sehingga fenomena ini dapat ditekan. Oleh sebab itu penelitian ini bertujuan ialah  menemukan  dan  mengkaji pendidikan keluarga dan lingkungan sosial  yang berperan untuk mencegah maraknya orientasi seks LGBT ditengah masyarakat sosial serta menghubungkannya dengan dasar Alkitab dari 1 Korintus 15:33: Janganlah kamu sesat: Pergaulan yang buruk merusakkan kebiasaan yang baik. Penelitian ini menggunakan metode kualiatif yang sifatnya deskriptif dengan melakukan wawancara mendalam dari ahli yang ditentukan sebagai informan dengan menggunakan pendekatan studi pustaka dan Alkitab. Hasil dari penelitian ini menunjukan bahwa orientasi seks LGBT disebabkan kurangnya dijalankannya fungsi pendidikan keluarga dan pengaruh lingkungan sosial yang tidak baik.

Pendidikan Keluarga, Lingkungan sosial, LGBT, 1 Korintus 15:33
Faktor-faktor yang Mempengaruhi Perilaku Merokok Pada Remaja Putera Kelas XI di SMK Sasabila Kota Jambi
Authors: Liza  , Fitri Aulia  , Erika
Published: January 2022

Dalam setiap kepulan asap rokok terkandung ± 4000 racun kimia berbahaya dan 43 diantaranya bersifat karsinogenik (merangsang tumbuhnya kanker). Penelitian di Amerika Serikat yang melibatkan 6813 pria, menunjukkan hasil bahwa 50% perokok berat meninggal pada usia 47,5 th dan 50% perokok sedang meninggal pada usia 56 tahun.. Adapun tujuan penelitian ini adalah Untuk Mengetahui ada nya hubungan antara perilaku merokok dengan pengaruh orangtua, pengaruh teman dan faktor iklan. Dan desain penelitian yang digunakan adalah survey analitik dengan pendekatan Cross Sectional. Pengambilan sampel di lakukan secara Total Sampling yaitu seluruh populasi dijadikan sampel. Analisa data secara univariat dilakukan untuk mengetahui distribusi frekuensi dan persentase dari variabel perilaku merokok pada remaja putera, pengaruh orangtua, pengaruh teman dan faktor iklan, sedangkan analisis data secara bivariat ini dilakukan untuk mengetahui hubungan antara variabel independen dan variabel dependen di analisis dengan uji statistikChi-Squer dimana α =0,05 dan dengan batas kemaknaan bila p value ≤ 0,05 artinya ada hubungan yang bermakna dan bila p value > 0,05 tidak bermakna. Dari hasil univariat menunjukan responden merokok 12 responden (34,4%) dan tidak merokok 23 responden (65,7%),  pengaruh orangtua yang baik 21 responden (60,0%) dan tidak baik 14 responden (40,0%), pengaruh teman yang baik 16 responden (45,7%) dan yang tidak baik 19 responden (54,3%), responden merokok karena faktor iklan 11 responden (31,4%) dan tidak 24 responden (68,6%), dan hasil bivariat menunjukan pengaruh orangtua baik yaitu 3 responden (13,6%) tidak yaitu 9 responden (69,2%), pengaruh teman baik yaitu 10 responden (62,5%) dan tidak yaitu 2 responden (10,5%), faktor iklan yang ya yaitu 8 responden (72,7%) dan tidak yaitu 4 responden (16,7%). Orangtua harus lebih memperhatikan perkembangan anak, terutama remaja putera terhadap kejadian perilaku merokok pada remaja putera yang semakin memarak terutama dikalangan anak sekolah pertama (SMK).
Penanganan Efek Samping Kontrasepsi Suntik 3 Bulan Pada Akseptor KB Suntik
Authors: Yuhemy Zurizah  , Juni  , Lara Arah Dea
Published: January 2022

Berdasarkan data Badan Pusat Statistik  (BPS) jumlah penduduk Indonesia adalah sebesar 219,2 juta jiwa, dengan rata-rata laju pertumbuhan penduduk sekitar 1,8 persen pertahun. Salah satu cara untuk menekan laju pertumbuhan penduduk adalah melalui program keluarga berencana yaitu menurunkan tingkat kelahiran. Tujuan penelitian ini adalah bagaimana penanganan efek samping kontrasepsi suntik 3 bulan pada akseptor KB Suntik. Desain penelitian yang digunakan adalah penelitian kualitatif dengan pendekatan fenomenologi. Penelitian kualitatif merupakan suatu penelitian yang bersifat eksploratif terhadap suatu gejala atau fenomena yang memberikan gambaranformatif dari keadaan yang menjadi faktor kausatif fenomena tersebut. Fokus penelitian ini didasarkan pada penemuan fakta suatu fenomena berdasarkan perspektif informan. Informan diseleksi menggunakan teknik sampling purposive yaitu informan yang mempunyai karakteristik sesuai dengan tujuan penelitian. Kesimpulan dalam penelitian ini adalah Pada pengetahuan ibu didapatkan 2 tema yaitu tema 1  tentang tujuan ibu dalam penggunaan KB suntik dan tema 2 tentang konsep dasar KB suntik 3 bulan. Informan  mengatakan bahwa tujuan penggunaan KB suntik yaitu untuk mencegah kehamilan dan dua dari keempat informan mengatakan bahwa kb suntik dapat mengatur jarak kehamilan. Pada kategori 1 tema 2, keempat informan mengatakan bahwa lokasi penyuntikan yaitu di bokong. Kemudian untuk kategori 2 informan mengatakan keuntungan  kb suntik 3 bulan yaitu dapat mencegah kehamilan dalam waktu yang cukup lama, aman digunakan untuk ibu yang sedang menyusui, dan efektif.Pada efek samping  kb suntik  3 bulan yang dialami ibu primipara  didapatkan  1 tema yaitu  tema 3 tentang efek samping yang dialami ibu primipara. Informan  mengalami sakit kepala sejak menggunakan kb suntik 3 bulan dan keluar bercak darah sedikit-sedikit, telat mensturasi, dan tidak mengalami mensturasi selam 2 bulan setelah disuntik. Pada tindakan yang dilakukan dalam penanganan efek samping kontrasepsi suntik 3 bulan oleh ibu primipara didapatkan 1 tema yaitu tema 4 tentang penanganan efek samping kb suntik 3bulan. Informan mengatakan bahwa tindakan yang mereka lakukan untuk mengatasi efek samping kb suntik 3 bulan  yaitu  tiduran atau istirahat dan minum bodrek untuk mengatasi sakit kepala, dan informan mengatakan kalau mereka pernah mengganti dengan kb pil karena tidak tahan mengalami efek samping tersebut
Pemanfaatan Instagram sebagai Media Komunikasi Pemasaran dalam Membangun Brand Image
Authors: Wainira Maria A.D. , Liliweri Yohanes K.N. , Mandaru Silvania S.E.
Published: January 2022

Maraknya penggunaan media sosial khususunya Instagram sekarang ini, membuat banyak pelaku bisnis di luar sana yang memanfaatkan dan menggunakan Instagram untuk memasarkan produk/brand mereka. Begitupula yang dilakukan oleh Kopi Papa Ganteng. Sebagai sebuah bisnis minuman kopi lokal, brand image yang positif dan kuat sangat diperlukan dan sangat penting bagi Kopi Papa Ganteng karena dapat menjadi hal yang memebedakannya dengan para pesaing atau brand sejenis lainnya. Penelitian ini sendiri bertujuan untuk mengetahui dan mendeskripsikan komunikasi pemasaran Kopi Papa Ganteng dalam membangun brand image melalui pemanfaatan media sosial Instagram. Teori yang digunakan dalam penelitian ini adalah marketing mix theory yang di dalamnya terdapat 4 konsep yaitu product, price, place, dan promotion. Penelitian ini menggunakan metode deskriptif kualitatif, dengan Subjek penelitiannya yaitu akun Instagram @kopipapaganteng dan Pemilik dari Kopi Papa Ganteng. Dimana data penelitian dikumpulkan melalui teknik wawancara, observasi dan juga dokumentasi. Hasil penelitian menunjukan bahwa kegiatan komunikasi pemasaran Kopi Papa Ganteng dalam membangun brang iamge melalui Instagram melibatkan semua elemen bauran pemasaran atau marketing mix yakni product, price, place, dan promotion. Dimana konsep produk, harga, tempat, dan kegiatan promosi yang dilakukan, dapat memberikan citra yang baik bagi Kopi Papa Ganteng. Kemudian dalam melakukan komunikasi pemasaran, Kopi Papa Ganteng memanfaatkan dengan baik fitur-fitur yang ada di Instagram, seperti fitur Instagram story, fitur highlights, fitur unggahan foto atau  video, fitur caption dan hastag.
Strategi Komunikasi Komunitas Film Kupang
Authors: Da Costa Shara M. , Aloysius Liliweri , Andung Petrus A.
Published: January 2022

Film tidak hanya sebagai media hiburan tetapi juga sebagai instrument edukatif, informasif, bahkan persuasif. Beragam macam film kini dapat dikonsumsi dengan mudah, baik film industri komersil maupun film independen. Di Indonesia sendiri, perkembangan film yang dinamis dan sempat mengalami kemerosotan, kini berangsur membaik. Dimulai dari gerakan para pegiat film independen yang tidak ingin film-film Indonesia redup dan mati, akhirnya dapat menunjukan wajah perfilman Indonesia di kancah Internasional. Menariknya, masih banyak daerah di Indonesia yang kekurangan akses film independen, dan Kota Kupang salah satunya. Hadirnya bioskop alternatif ‘Jumat Di Garasi’ oleh Komunitas Film Kupang diharapkan dapat menjawab kebutuhan penonton dan sineas di Kota Kupang. Penelitian ini bertujuan untuk mendeskripsikan strategi komunikasi Komunitas Film Kupang dalam mendorong program ‘Jumat di Garasi’ sebagai Bioskop Alternatif di Kota Kupang. Teori yang digunakan adalah teori AIDDA. Penelitian ini merupakan penelitian kualitatif dengan metode studi kasus dan subjek penelitiannya adalah badan pengurus Jumat di Garasi. Teknik pengumpulan data yang digunakan adalah wawancara mendalam, observasi dan dokumentasi. Teknik analisis data yang digunakan adalah teknik analisis data kualitatif dengan teknik pemeriksaan keabsahan data dilakukan dengan triangulasi sumber dan triangulasi metode. Hasil penelitian ini menunjukkan bahwa strategi komunikasi yang dilakukan Komunitas Film Kupang adalah dengan menentukan khalayak, mengelola pesan, menentukan metode komunikasi dan memilih media komunikasi dengan menggunakan strategi perencanaan, pelaksanaan dan evaluasi. Sementara model komunikasi yang digunakan adalah model komunikasi persuasif, informatif dan edukatif dengan memanfaatkan media sosial sebagai media komunikasi.
Resistencia comunitaria como pedagogía emergente para una Educación Ambiental de la Sustentabilidad: Reflexiones desde Jilotzingo y Temacapulin, México
Authors: Rodríguez Martínez Víctor Hugo , Sánchez Barreto Rafael Fernando
Published: January 2022

Ante la creciente conflictividad socioambiental en México derivada de megaproyectos infraestructurales, que perciben a la naturaleza como objeto mercantil y cosifican las relaciones armónicas que grupos poblacionales establecen con ella, han surgido cada vez con más fuerza resistencias comunitarias que enfrentan dicha lógica instrumental y mecanicista promovida por el modelo de desarrollo hegemónico. Dichas resistencias están generando sentidos de vida alternos al discurso neoliberal, donde la defensa del territorio y la lucha por mantenerse como colectividades con sus saberes y prácticas ancestrales ancladas a un territorio, promueven una pedagogía emergente que apunta a procesos formativos de la población en una sustentabilidad para la vida. Por lo anterior, los objetivos del presente trabajo son conocer y analizar dos resistencias comunitarias desde la voz de actores sociales clave en ellas, para comprender los aprendizajes que se están generando en sus propios territorios a fin de construir procesos situados de sustentabilidad. Como conclusión anticipada se resalta que, a través de una educación ambiental genuina basada en la resistencia comunitaria, se están forjando seres humanos comprometidos con todas las formas de vida y defensores de ellas, comprometidos con la paz, el respeto, la inclusión, la interculturalidad, en suma, con la edificación de otros mundos posibles y sustentables.
Nicho de artefatos semióticos e externalismo cognitivo
Authors: Atã Pedro , Queiroz João
Published: January 2022

Como fornecer um locus de observação para a noção formal de semiose? Temos sugerido que as noções de nicho e artefato são especialmente capazes de atualizar a tese, formulada por Peirce, de que não se pode pensar sem signos externos, associando-a a novos métodos e resultados empíricos e teóricos. Neste artigo, introduzimos a noção de nicho de artefatos semióticos. Em nossa abordagem, cognição é semiose, ação de signos, em um processo que toma a forma de construção de nichos. Em comparação com a noção corrente de artefato, artefatos semióticos são processos semióticos, signos-em-ação. Nichos de artefatos semióticos são espaços estruturados de condições fundamentais para estabilidade da semiose, como situacionalidade (co-localização) e distribuição temporal entre comunidades de agentes, artefatos, e seus ambientes. Nichos de artefatos semióticos oferecem condições para emergência de hábito e surpresa na semiose/cognição. Esta linha de investigação sugere uma semiótica cognitiva baseada em relações dinâmicas, distribuídas e emergentes.
Numerical analysis of wave propagating in a periodic layered structure
Authors: Fukuchi Takaaki , Mori Naoki , Hayashi Takahiro
Published: January 2022

Controlling sound fields is a key technology for noise removal, acoustic lenses, energy harvesting, etc. This study investigated the control of sound field by a periodic layered structure. At first, we formulated the wave propagation in a periodic layered structure and proved that the wave fields constructed by the periodic boundary conditions are limited to plane wave modes with discretely different propagation directions. Numerical calculations clarified that the desired plane wave mode can be obtained in the transmitted wave through an intermediate thin-plate stacked region in a periodic layered structure, in which Lamb waves travel in each plate at different phase velocities and create phase difference at the exit of the intermediate thin-plate region. Further numerical investigations revealed that tuning frequency and the length of the thin-plate region provides wave field more dominantly with a single wanted plane wave mode.
Room temperature fabrication and post-annealing treatment of amorphous Ga2O3 photodetectors for deep-ultraviolet light detection
Authors: Zhang Tan , Guan Denggao , Liu Ningtao , Zhang Jianguo , Zhang Jinfu , Guo Chenyu , Qiu Mengting , Yuan Qilong , Zhang Wenrui , Ye Jichun
Published: January 2022

This work fabricates deep-ultraviolet (DUV) photodetectors (PDs) with a metal-semiconductor-metal structure based on radio-frequency sputtered amorphous Ga2O3 films at room temperature. The Ga2O3-based PD exhibits a low dark current of 1.41 × 10−11 A, a responsivity of 1.77 A W−1 and a fast rise response time of 114 ms. A series of annealing treatments with different atmospheres have been found effective to reduce the oxygen vacancy concentration, exhibiting a trade-off effect between the responsivity and the response time. These results demonstrate a cost-effective room-temperature approach for fabricating amorphous Ga2O3-based PDs and developing possible post-synthetic methods for tuning the PD performance.
Discretionary loan loss provision in the Moroccan banking sector: The role of governance mechanisms
Authors:   Laboratory of Finance, Audit and Management Research, LAREFAG, ENCG, Abdelmalek Essaadi University, Tetouan, Morocco, El Mokrani Yousra , El Idrissi Issam ,   Laboratory of Finance, Audit and Management Research, LAREFAG, ENCG, Abdelmalek Essaadi University, Tetouan, Morocco, Alami Youssef ,   Laboratory of Finance, Audit and Management Research, LAREFAG, ENCG, Abdelmalek Essaadi University, Tetouan, Morocco
Published: January 2022

Abstract Purpose: The present paper aims to examine the impact of corporate governance mechanisms on earnings management extent in the Moroccan banking sector. Research methodology: This research investigates the relationship between listed banks' governance mechanisms and earnings management in the CSE over the period 2017-2020. This study relies on a two-step quantitative approach, which consists firstly of estimating discretionary loan loss provisions to measure EM, then presenting the association between banks’ governance mechanisms and discretionary loan loss provisions. Results: The findings indicate that board size, gender diversity, audit committee’s independence, and state ownership constraint EM practices among the Moroccan listed banks. While other governance mechanisms, such as institutional ownership and board activity, seem to have no significant effect on restraining managers’ discretionary behavior. Limitations: Many qualitative and quantitative factors could influence discretionary loan loss provisions and not only the used variables in this research. Contribution: This research reveals the need to maintain the vigilant supervision of the regulatory framework to limit these opportunistic practices in the local banking industry. Also, our study has important implications for establishing a new set of governance requirements such as board diversity in Morocco.