bluuebunny/crossref_metadata_2025 huggingface dataset:
The effects of perceived ease of use, electronic word of mouth and content marketing on purchase decision
Authors: Asnawati Asnawati , Nadir Maryam , Wardhani Wirasmi , Setini Made
Published: November 2021

Purchasing decisions on the Traveloka application has experienced a significant decline since the Covid-19 pandemic outbreak. Ticket returns and refunds that occur due to travel restrictions have resulted in a decline in Traveloka's brand image. This study aims to analyze how brand image mediates the effect of perceived ease of use, electronic word of mouth and content marketing towards ticket purchasing decisions on the Traveloka application which was conducted on 130 respondents using the Traveloka application. The research was conducted in June 2021 with data analysis using SmartPLS 3.2.0 software. The results show that perceived ease of use had a negative impact on purchasing decisions, either directly or indirectly through brand image. Electronic word of mouth had a positive impact on purchasing decisions either directly or indirectly through brand image. Content marketing had a negative and significant impact on purchasing decisions, while indirectly through brand image had a positive and significant impact. The role of brand image was very important in increasing the effect of perceived ease of use, electronic word of mouth and content marketing towards purchasing decisions.
Electronic government public value of public institutions in Jordan
Authors: Alhanatleh Hasan , Aboalganam Khaled , Awad Hussain
Published: November 2021

Substantially, the theory of e-government public value (PV-EGOV) has been treated as a hot topic to be explored insightfully. This research comes to be considered as the launching point to empirically evaluate the creation of PV-EGOV in Jordan. The main aim of this research is to investigate the factors affecting the PV-EGOV in the context of Jordan. Information System Success Model (IS success model) was selected to determine the factors affecting the e-government public value in Jordan through the quality factors (system, information, and service) and their role in citizens' intention in use and satisfaction of the e-government. The structural Equation Model (SEM) approach was harnessed to obtain the results. The results indicated that the most critical determinant factor that affected the PV-EGOV was service quality. The current article has theoretical and practical implications for public institutions in Jordan. The future work trends are established in their specific section of this article.
What drives millennials and zillennials continuously using instant messaging? Perspective from Indonesia
Authors: Rahmayanti Putu Laksmita Dewi , Dharmanegara Ida Bagus Agung , Yasa Ni Nyoman Kerti , Sukaatmadja I Putu Gde , Pramudana Komang Agus Satria , Rahanata Gede Bayu , Giantari I Gusti Ayu Ketut , Martaleni Martaleni
Published: November 2021

This study proposes to explore the relationship between perceived risk, subjective norm, perceived value, and continuous usage intention via trust as a mediating variable. This research applied a survey which involved 320 IM users (160 from millennials and 160 from Zillennial) in Indonesia. The literature’s existing scales were used to operationalize the constructs proposed in this study. The analyses were conducted using partial least squares structural equation modeling (PLS-SEM) to test hypotheses. The results of the study show that there are differences in the results of the influence of perceived risk on continuous usage intention in the Millennial and Zillennial generations. The results of the study found that continuous usage intention received negative direct impact from perceived risk, positive direct effect from subjective norm, perceived value, and trust on Millennial. In addition, continuous usage intention received negative and not significant direct impact from perceived risk, positive direct effect from subjective norm, perceived value, and trust on Zillennial. The results are useful for instant messaging management into formulating strategies to retain their users in Indonesia. These findings provided theoretical and managerial contributions as well as future research directions.
The role of social media marketing and brand image on smartphone purchase intention
Authors: Savitri Citra , Hurriyati Ratih , Wibowo Lili Adi , Hendrayati Heny
Published: November 2021

The purpose of this study was to analyze the relationship between Social Media Marketing and Brand Image, Social Media Marketing relationship and Purchase Intention, Brand Image Relationship and Purchase Intention and finally, the relationship between Social Media Marketing and Purchase Intention through Brand Image. The approach in the research used is a quantitative approach using PLS-SEM SmartPLS software as a data processing tool. In this study, the data collection technique was carried out using a questionnaire or online questionnaire which was distributed to 234 respondents of Millennial Smartphone Consumers in Banten Indonesia. Sampling system was accomplished with a snowball sampling method. Based on the results of hypothesis testing, it was found that there was a positive and significant relationship between Brand Image (BRI) and Purchase Intention. There was also a positive and significant relationship between Social Media Marketing and Brand Image. However, there was an insignificant relationship between Social Media Marketing and Brand Image while there was a significant relationship between Social Media Marketing and Purchase Intention through Brand Image as Mediator.
E-HRM practices and sustainable competitive advantage from HR practitioner’s perspective: A mediated moderation analysi
Authors: Shamout Mohamed Dawood , Elayan Malek B. , Rawashdeh Adnan M. , Kurdi Barween Al , Alshurideh Muhammad
Published: November 2021

This paper seeks to investigate the impact of Electronic Human Resource Management (e-HRM) practices on attaining Sustainable Competitive Advantage (SCA) in the context of the Jordanian Industrial Sector (JIS) and identify the mediating role of e-HRM Perceived Usefulness (PU) and e-HRM Perceived Ease of Use (PEOU). Furthermore, it investigates the moderating role of User Satisfaction and e-HRM Continuance Usage Intention. To achieve the paper objectives, a Mediated-Moderation Model was designed. The researchers distributed (750) questionnaires, (615) questionnaires were returned and validated for analysis in HRM and development divisions and based on a Census method with the response rate was about (82%). The ‘Structural Equation Modeling’ (SEM) methodology was used, and for analysis, SPSS and Amos were applied. The results indicated that e-HRM practices had significant influence on SCA. The paper also demonstrated that there was a significant mediate effect of TAM constructs on the relationship between e-HRM practices and SCA. Finally, the findings indicated that the user satisfaction and e-HRM continuance usage intention did not moderate the relationship between e-HRM-PEOU and PU and SCA path.
Short and/or long-term investment choice: Artificial intelligence analysis of the role of both or-ganizational and behavioral determinants
Authors: Hamza Fadhila
Published: November 2021

This paper shows empirically the impact of organizational and behavioral determinants on the CEO's investment horizon choice, using artificial intelligence explanatory methods. We apply our approach to 100 Saudi firms. We test the effect of three organizational determinants: ownership concentration, board independence, and CEO remuneration system; and three behavioral determinants: myopia, the locus of control and commitment, on the CEO's investment horizon choice. The study’s key finding is that executives' commitment bias is the most important variable in terms of modal value that affects firms' long-term investment choice. We also find a positive and significant relationship between myopia and long-term investment choice, whereas the lowliest determinant of the horizon choice is the locus of control. More generally, these results show that CEOs who are likely to be the most myopic may display long-term behavior with the existence of high cognitive involvement.
Social media as a bridge to e-commerce adoption in Indonesia: A research framework for repurchase intention
Authors: Maskuroh Nihayatul , Fahlevi Mochammad , Irma Dasih , Rita Rita , Rabiah Arbi Siti
Published: November 2021

Consumers today are individuals who fulfill life needs such as shopping using e-commerce. In its fulfillment, consumers can change in terms of purchasing decisions from one e-commerce to another e-commerce. This requires the company to always have a good strategy to compete in a healthy manner in terms of business. To learn about the importance of social media marketing activity, this study will find out how much influence the social media marketing activity received by e-commerce companies has on brand equity, customer relationships and repurchase intention. In addition, the study will learn how much influence brand equity and customer relationship have on an e-commerce company's repurchase intention. In this study, the survey is conducted by distributing questionnaires to respondents online where the research sample has several questions related to the habits and behavior of respondents. This research uses a sample of 210 people who are domiciled in Indonesia. In the research model, the study uses Structural Equation Modeling (SEM) analysis and the software used for this research is IBM SPSS AMOS. The results of the influence of social media marketing activities have the largest positive influence on customer relationships, brand equity is the main and biggest factor that positively and significantly affects repurchase intention in this research model. The accumulated experience and knowledge of consumers about a brand is a factor that can influence consumers to repurchase the same brand. Brand equity not only provides immediate benefits, but also long-term benefits by retaining consumers to continue to repurchase their products. A strong brand will make consumers always remember the brand. The study explains that customer relationships do not have any significant effect on repurchase intention. The main function of customer relationships at first and now is to try to reach their consumers more broadly, especially related to purchases, but this is not proven in repurchases, especially in this study. Customer relationships in the study did not have any significant effect on repurchase intention.
Effect of Personal Characteristics on Social Accounting Initiatives: Evidence from Pakistan
Authors: Saeed Muhammad Shaharyar , Siddiqui Danish Ahmed
Published: November 2021

The research works with two separate but closely connected themes of individual employee behaviour and organisation-wide initiatives that are further broken down into two dimensions of Social Entrepreneurship Profile and Social Accounting (SA). This research study seeks to identify the social entrepreneurship profile that highlights the specific personal characteristics of employees working in an organisation; secondly, it attempts to understand how the broader initiatives that help today’s organisations become more socially responsible. Factors covered in Personal Characteristics included 1. Sociality, 2. Innovativeness, 3. Market-orientation, and 4. The ability of Identifying New Opportunities (INO). Social Accounting Initiatives included Internal Attitude (IA), and Subjective norms (SN), each is classified as1.Pragmatic, 2. Moral, and 3. Cognitive, as well as Perceived Behavioural Control (PBC). For this purpose, A survey was conducted of 75 firms, and their decision-makers 306. were surveyed about their characteristics as well as the social accounting initiatives in their firms, usinga close-ended questionnaire. Total of306 decision-makers was surveyedabout four employees per organisation. Dataset was analyzed using confirmatory factor analysis and structured equation modelling. The results suggested that innovativenessand INO seem to have a positive and significant impact on pragmatic and moralIA. As well as moral SN. Similarly, sociality and innovativeness positively affecting moral IA. Sociality also seems to be affecting moral IA, pragmatic SN, and PBC, however, it has a negative impact on cognitive SN. Market orientation also has a significant positive impact on cognitive IA and SN. Lastly, INO seems to affect Perceived Behavioural Control. Implications and limitations of the study are discussed.
動態競爭：後波特時代的競爭優勢
Authors: 陳明哲 陳明哲
Published: November 2021

《明哲文選》收錄了全球著名策略管理學者陳明哲教授過去三十年來的代表性著作，內容包含學術理論、企業實務以及傳承育人，展現了陳明哲教授在融合東方與西方、學術與實務、專業與人文的多重情境下，所開闢出來一條獨特的學術創業之路。這套文選旨在提供讀者瞭解與運用陳明哲教授「精一」和「雙融」的思想理念、實踐心得乃至系統方法，也期許讀者回歸自己，反思如何在變動的大環境下，找到安身立命之道。

《明哲文選》系列之二《動態競爭：後波特時代的競爭優勢》是整部文選的學術精粹，收錄了陳明哲教授創立的動態競爭理論體系中的15篇學術論文，系統性地呈現動態競爭理論的核心概念和方法，回顧動態競爭理論的發展過程，總結目前的研究發展，展望未來的發展趨勢，對於讀者在理論深化，以及實務應用方面都具有獨特的借鑑意義。
Comparação dos resultados gestacionais entre pacientes com síndrome antifosfolipídica trombótica e gestantes com trombose arterial sem síndrome antifosfolipídica
Authors: Rebelo Priscila Guyt , Lacerda Marcela Ignacchiti , Santos Flávia Cunha dos , Jesús Nilson Ramires de , Jesús Guilherme Ribeiro Ramires de
Published: November 2021

Introdução: Durante a gravidez, as mulheres têm aumentado de quatro a cinco vezes o risco de trombose, em comparação com quando não estão grávidas. Oitenta por cento de tromboses na gravidez ocorrem nas veias e aproximadamente 20% nas artérias, sendo estas incomuns na gravidez, mas passíveis de ter consequências devastadoras. Entre as pacientes que apresentam trombose arterial e/ou venosa recorrentes, recomenda-se a pesquisa de anticorpos antifosfolípides (aPL) como anticorpo anticardiolipina, anticoagulante lúpico, antibeta2-glicoproteína I para o diagnóstico da síndrome antifosfolipídeo (SAF). Objetivo: Comparar os resultados gestacionais de pacientes que apresentaram trombose arterial sem aPL com pacientes com SAF com história de trombose arterial. Materiais e métodos: Estudo de coorte com gestantes acompanhadas em um pré-natal de alto risco que apresentaram trombose arterial. As pacientes foram divididas em dois grupos: o primeiro consistiu em gestantes que apresentaram trombose arterial com pesquisa para SAF negativa; e o segundo em pacientes com SAF. A coleta de dados foi feita nos prontuários, por meio de um questionário redigido pelos próprios autores. Resultados e conclusão: Vinte e nove pacientes com trombose arterial foram incluídas no presente estudo, das quais 15 com história de trombose, 14 com aPL positivo, confirmando o diagnóstico de SAF (grupo 1), e 15 com aPL negativos (grupo 2). O grupo 1 tinha história obstétrica desfavorável em comparação com o grupo 2 (passado de um natimorto e 13 abortos e na gestação atual um óbito fetal versus ausência de óbitos fetais e nove abortos no grupo 2). Pacientes com trombose e aPL positivo (grupo 1) apresentaram com maior frequência na gestação atual crescimento intrauterino restrito (8x5, p=0,11), parto prematuro (5x1, p=0,03), oligodramnia (3x0, p=0,04), pré-eclâmpsia (6x2, p=0,04) e síndrome HELLP (1x0, p=NA). O peso médio do nascimento (2542±677 versus 3050±496, p=0,02) e a idade gestacional (37,02±3,9 versus 38,32±1,39, p=0,25) no parto foram significativamente menores no grupo 2. Conclusão: A presença de aPL em pacientes com história de trombose arterial está associada a piores resultados gestacionais, incluindo maior incidência de pré-eclâmpsia, parto prematuro e menor peso ao nascer, enquanto a história de trombose arterial com pesquisa para aPL negativa apresentou resultados gestacionais favoráveis. Nosso estudo sugere que a investigação para SAF é fundamental para o acompanhamento adequado de gestante com história de trombose vascular.
Diagnóstico clínico e ultrassonográfico de uma gestação ectópica abdominal: relato de caso
Authors: Vilhena Thyene de , Corrêa Kamilla Fernanda Babilônia , Esperidiao Alba Larissa dos Santos , Guiotti Isabela Furtado , Veiga Sabrina Carpanez
Published: November 2021

Introdução: Uma gravidez extrauterina é denominada de ectópica. A gestação ectópica abdominal caracteriza-se por uma implantação na cavidade peritoneal. É um evento raro, com incidência de 1,4% das gestações ectópicas e um a cada 10 mil nascimentos. Seus fatores de risco são dano tubário prévio, doença inflamatória pélvica, endometriose, reprodução assistida e multiparidade. A sua compreensão é de grande importância, visto que ela é a principal causa de mortalidade materna no primeiro trimestre, responsável por 4-10% de todas as mortes relacionadas à gravidez. Relato de caso: E.A.L., 36 anos, G2P0E1, com idade gestacional (IG) de nove semanas e seis dias pela data da última menstruação, foi atendida em pronto atendimento no dia 8 de abril de 2021 com queixa de dor em fossa ilíaca esquerda, sem sangramento ou outro sintoma. Relatava passado de gestação ectópica, dois anos antes, de localização em tuba uterina esquerda, quando foi submetida a salpingectomia à esquerda. Em seu primeiro ultrassom, com IG de cinco semanas, não foram revelados sinais de gestação intrauterina. Ao exame físico, a paciente apresentava dor discreta à palpação abdominal de fossa ilíaca esquerda e toque vaginal bimanual não doloroso. Apesar do exame, no momento, não ser rico para gestação ectópica e a dor se localizar no mesmo local da gestação ectópica anterior, optou-se por solicitar um ultrassom endovaginal por causa dos fatores de risco e da não visualização de saco gestacional com IG de cinco semanas. A ultrassonografia mostrou a presença de saco gestacional em hipocôndrio esquerdo, medindo 28,5 mm e contendo embrião de 24,7 mm, com batimentos cardíacos presentes e pequena quantidade de líquido livre na pelve. A paciente manifestou o desejo de procurar outro serviço apesar das orientações dos riscos do deslocamento e da evasão. Foi submetida a laparotomia em 9 de abril de 2021, em outro hospital. Conclusão: Em razão da localização variável no abdômen, a gravidez abdominal está associada a uma ampla gama de sinais e sintomas. Assim, um alto índice de suspeita, considerando-se os fatores de risco de cada paciente, é importante para se fazer o diagnóstico. A clínica de uma gestação ectópica abdominal nem sempre é clássica. O sangramento vaginal, por exemplo, é menos frequente, mas em alguns casos também pode estar presente. Percebe-se que uma avaliação global da paciente se faz necessária. As gravidezes abdominais na maioria dos casos são interrompidas, pois o potencial de parto de um bebê saudável é baixo e o risco de complicações maternas é alto. Diante disso, o diagnóstico precoce reduz complicações e permite o sucesso terapêutico.
Esteatose hepática aguda na gestação: um relato de caso
Authors: Moreira Paullini Silva , Deus Suelen Peixoto Marinho de , Laranjeira Claudia Lourdes Soares , Brandão Lorena Ventura , Faria Melina Cançado Araújo
Published: November 2021

Objetivo: Revisar o diagnóstico e o tratamento da esteatose hepática aguda da gestação (EHAG). Relato de caso: Paciente do sexo feminino, 30 anos, primigesta na 36ª semana de gestação, pré-natal de risco habitual, foi admitida com relato de icterícia, dor abdominal difusa e náuseas. Negava febre, colúria, acolia fecal ou prurido. Sem alterações no apetite. Movimentação fetal presente. Sem perdas vaginais. Ao exame da admissão, apresentava-se estável hemodinamicamente, normotensa, ictérica 3+/4+ e afebril. Batimentos cadíacos fetais de 145 bpm, dinâmica uterina ausente e tônus uterino normal. Os exames iniciais mostraram alteração na função hepática (FA 560 / GGT 206), hiperbilirrubinemia com predomínio de bilirrubina direta (BD) (bilirrubina total 10 / BD 6,21), RNI 2,13, tempo de tromboplastina parcial ativado (TTPa 52,4 / controle 27) e plaquetas de 135.000. Foi hospitalizada e indicou-se a interrupção da gestação, questionando-se EHAG. O parto não teve intercorrências e o recém-nascido foi encaminhado para o alojamento conjunto. Resultados: A paciente evoluiu com piora dos exames laboratoriais e hipoglicemia e foi encaminhada ao centro de terapia intensiva (CTI), onde permaneceu por quatro dias. Recebeu alta do CTI e manteve boa estabilidade hemodinâmica. A alta hospitalar ocorreu no 8º dia pós-parto e a paciente manteve o acompanhamento ambulatorial com equipe da clínica médica e da obstetrícia. Conclusão: A EHAG é um diagnóstico de exclusão, e sua identificação e tratamento precoces são essenciais para melhorar a sobrevida da paciente e do feto.
Gestação ectópica: dez semanas
Authors: Santos Isabella Soares da Costa dos , Oliveira Ligia Cardoso de
Published: November 2021

Introdução: O desenvolvimento subsequente e a implantação do embrião fora do revestimento uterino são definidos como gravidez ectópica, que tem uma ampla variedade de apresentações, por exemplo, de hemoperitônio agudo a gravidez ectópica crônica. O caso apresentado é um exemplo incomum de gravidez ectópica com grande hematosalpinge e sintomas clássicos. Relato de caso: Paciente M.D.S.U.F., 39 anos de idade, G4/P3 (2PN+1PC), procurou maternidade em razão de dor abdominal súbita e sinais de instabilidade hemodinâmica. Ao exame físico, abdome distendido, extremamente doloroso, com sinais de peritonite. Trouxe gonadrotofina coriônica humana beta (beta-HCG) qualitativo positivo externo. A idade gestacional pela última menstruação correspondia a 10 semanas e 2 dias. Foi submetida a laparatomia exploratória de urgência, que evidenciou grande quantidade de líquido hemorrágico no abdome, gravidez ectópica à direita com presença de ruptura extensa de trompa direita em sua porção ístmica, com feto de cerca de 10 cm, aparentemente do sexo masculino, e massa placentária aderida a ovário ipsilateral, tuba uterina esquerda dilatada e endurecida, demais estruturas pélvicas sem anormalidade. Após drenagem do líquido hemorrágico, foram realizadas salpingectomia com ooferectomia à direita e retirada de feto e placenta. Foram foi transfundidos 400 mL de concetrado de hemácia, com melhora do sangramento. A placenta foi encaminhada ao histopatológico e a paciente à terapia intensiva. Conclusão: Até 2% das gestações podem ser gravidezes ectópicas. A prevalência desse tipo de gravidez chega a 18% com as mulheres que se apresentam ao pronto-socorro com dor abdominal e sangramento vaginal no primeiro trimestre ou ambos. Apesar das melhorias no diagnóstico e no tratamento, a ruptura da gravidez ectópica continua a ter morbidade e mortalidade significativas. As gravidezes ectópicas rotas, de 2011 a 2013, foram responsáveis por 2,7% de todas as mortes relacionadas à gravidez e, além disso, são a principal causa de mortalidade relacionada à hemorragia. Casos de gestações ectópicas abdominais grandes foram publicados anteriormente. No entanto, a literatura é limitada sobre gestações ectópicas tubárias grandes. A detecção precoce da gravidez ectópica é essencial para a redução da morbimortalidade materna. A ultrassonografia é uma ferramenta crucial, pois pode diminuir o tempo para o diagnóstico e direcionar o atendimento ao paciente, especialmente em condições de risco de vida. Ela pode detectar a ruptura da gravidez ectópica e o sangramento intra-abdominal em curso, o que pode ser um sinal de necessidade de intervenção cirúrgica. Este relato é importante porque não existem muitas publicações detalhando uma gravidez tubária com mais de 10 semanas, como visto aqui. Além disso, a ruptura da gravidez ectópica pode causar sangramento intraperitoneal e choque hemorrágico, sendo necessário detecção precoce da gravidez ectópica para o controle da morbimortalidade materna.
Effect of hot climate of Saudi Arabia on physical and mechanical properties of single use polypropylene packaging films
Authors: Gopanna Aravinthan , Thomas Selvin P. , Rajan Krishna Prasad
Published: November 2021

Two types of single use plastic films were used to study the effect of hot climate conditions of Saudi Arabia during a six-month experiment. The objective of the study is to understand the degradation behavior of the single use packaging films under direct sunlight exposure with variation in humidity. The films were kept on a specially designed experimental setup. The films were analyzed every month with respect to morphology, spectroscopy, thermal and mechanical properties. The microscopic images showed initiation of cracks on the exterior of films. Mechanical properties such as tensile strength and tensile modulus were measured and a decrease of 17 and 7% from the virgin material was noticed. The thermal and flammability properties also showed a decrease which confirmed the ageing of the films due to the climatic conditions. The water contact angle showed 20% decrease which indicated the effect of the weathering conditions to make the films less hydrophobic. The degraded packaging films after the exposure could be used as recycling component for the preparation of reusable single use plastic compounds.
Dört Yaşlı Erkek Bir Kedide Nekrotik Glossitis Olgusu
Authors: HATİPOĞLU Fatih , TAŞ Abuzer , ŞEN İsmail , AİTMYRZA KYZY Aiperi , ABDIMANAP UULU Nur
Published: November 2021

Dört yaşlı erkek melez bir kedide dilin dorsalinden alınan bir kitlede nekrotik glossitis olgusu tanımlandı. Yaklaşık 1.5 sene önce dilde bir kitle nedeniyle operasyon yapıldığı bildirildi. 1 ay öncesinde ise kedinin yemek yerken ağızdan fazla miktarda salya ve bazen de kan geldiğinin gözlenmesi üzerine hayvan sahibi tarafından dilde bir kitle oluşumu fark edilmiş ve kedinin muayenesi Kırgızistan-Türkiye Manas Üniversitesi Veteriner Fakültesi Kliniğinde yapılmıştır. Yapılan muayenede, gıda alımını ve yutkunmayı kısmen engelleyecek şekilde dilin kaudal bölgesinde ve dorsal yüzeyinden taşkın görünümde bir kitle gözlendi ve bu kitlenin operasyonla alınmasına karar verildi. Kitle sağlam doku aleyhine elektrokoter ile ekstirpe edildi. Alınan kitle Patoloji Laboratuvarına gönderildi. Kitle, 1,2x1,5x2 cm ebatlarında ve sert kıvamdaydı. Kitlenin yüzeyinde yer yer eroziv-ülseratif alanlar gözlendi. Kesit yüzünde ise 2-3 mm çapında sarımsı-gri renkte odaklar dikkati çekti. Mikroskobik incelemelerde; epitel hücrelerindeki dejenerasyon, nekroz ve deskuamasyon sonucu oluşan erozyon ve ülserler gözlendi. Bu alanlarda propriyada çoğunluğu nörtofil granülositlerden oluşan yangısel hücreler ile bağ doku artışları dikkati çekti. Dil kasları arasına serpilmiş olarak farklı büyüklüklerde pembe renkte nekrotik odaklar ile bu odakların çevresinde yangı hücrelerinden oluşan bir kuşak ve bağ doku artışları gözlendi. Sunulan olguda, tümör şüphesiyle alınan kitlede nekrozlarla birlikte gözlenen değişiklikler sonucunda nekrotik glossitis tanısı konmuştur. Ülserli ve kanamalı görünümde olan kitleler genellikle tümöral oluşumlar olarak yorumlanır. Ancak bu olguda da görüldüğü gibi tümör olarak değerlendirilen benzer görünümdeki kitlelerde nekrotik- yangısel değişikliklerin de dikkate alınması gerektiği kanısına varılmıştır. Benzeri durumlar için klinisyenlerin konuya dikkatini çekmek ve veteriner hekimliğe katkı sağlanması amacıyla olgunun sunulması uygun bulunmuştur.
A formação de futuros professores de ciência: prática de ensino para desenvolver o pensamento crítico
Authors: Sepini Ricardo Pereira , Maciel Maria Delourdes , Alonso Ángel Vázquez
Published: November 2021

Este trabalho apresenta os resultados de uma investigação realizada com graduandos do curso de Ciências Biológicas (Licenciatura) da Universidade Federal de São João del-Rei / Brasil. Como metodologia, ajustou-se a um desenho de pré-teste e pós-teste com os grupos controle e experimental e uma intervenção didática com o grupo experimental. Como instrumentos utilizamos questões do “Cuestionario de opiniones sobre ciencia, tecnología y sociedade” na avaliação pré e pós-teste e na intervenção didática a disciplina prática de ensino de ciências. Os resultados apresentaram diferencias não significativas estatisticamente e algumas possíveis contribuições do pensamento crítico para melhorar a formação de professores são discutidas.
Gestão do conhecimento: percepção dos discentes em relação ao ensino de conteúdo contábil
Authors: Rodrigues Barroso Daniel Berg , De Araújo Mimo Ronei , Costa Matos Gleimiria , Dos Santos Arenas Marlene Valério , Rios De Almeida Vanessa Fernanda
Published: November 2021

Esta pesquisa tem como objetivo verificar o nível de compreensão dos discentes dos cursos de Administração e Ciências Econômicas da Fundação Universidade Federal de Rondônia (UNIR) em relação ao conteúdo contábil ensinado no decorrer desses cursos. A pesquisa é classificada como: quantitativa e qualitativa quanto a abordagem do problema e descritiva quanto ao objetivo. Em relação aos procedimentos técnicos utilizados classifica-se como levantamento aplicado por meio de um questionário, aos discentes matriculados no sexto e sétimo período do curso de Administração, e os discentes do quinto e sexto período do curso de Ciências Econômicas. O resultado da pesquisa indica que a maioria dos discentes concordam com a importância dos conteúdos ministrados para sua formação e futuro profissional. A importância das disciplinas de conteúdo contábil e a capacidade de síntese e clareza também foram pontos relevantes. Em relação as questões abertas percebem-se que os discentes deram uma maior importância na assimilação do conteúdo.
Produção de uma cartilha educativa sobre a prevenção e controle da hipertensão arterial
Authors: Arruda Alcínia Braga de Lima , Oliveira Hoberlania Vieira Alves , Maia Adriano Evangelista , Maia Isabelle de Fátima Vieira Camelo , Sousa Emanuela Kelly Silva , Sousa Josyelle Moreira , Sousa Arthur Chagas , Gonzaga Luis Ednilson Maciel
Published: November 2021

O objetivo deste trabalho foi descrever à elaboração de uma cartilha educativa para idosas. Trata-se de um estudo descritivo, do tipo relato de experiência, realizado nos meses de julho a agosto de 2021, o qual descreve o processo da produção do material educativo. A cartilha foi confeccionada acompanhando as seguintes etapas: definição do tema da cartilha, levantamento bibliográfico do assunto e a montagem da cartilha propriamente dita. Desse modo, foi possível colocar nesta cartilha informações importantes que permitem o reconhecimento da hipertensão arterial, seus sintomas, prevenção e controle. O resultado foi uma cartilha intitulada de “Prevenção e Controle da Hipertensão Arterial”, composta por um total de 16 páginas, com a parte externa representada por elementos pré-textuais como a capa, elaboração (identificação do autor do trabalho) e sumário; por elementos textuais representados pelo conteúdo, seguida pelos elementos pós-textuais, compostos pelas referências e por uma página de anotações do controle das medidas da pressão arterial da idosa. Na confecção da cartilha utilizou-se todas as sugestões sugeridas pela literatura especializada, conseguindo elaborar uma ferramenta didática simples e de fácil entendimento.
FORMULATION AND EVALUATION OF NATEGLINIDE NANOSPONGES
Authors: Bakliwal A. A , Jat D. S. , Talele S. G. , Jadhav A. G. ,   Sandip Institute of Pharmaceutical Science, Mahiravani, Nashik - 422 213. Maharashtra, India.
Published: November 2021

The objective of the present study was to produce extended release nateglinide nanosponges for oral delivery. Preparation of nanosponges leads to solubility enhancement. Nateglinide is a BCS Class II drug, having low solubility. So, to increase the solubility of nateglinide it is formulated into nanosponges. Nanosponges using ethyl cellulose as a polymer and dichloromethane as a cross-linker were prepared successfully by ultra-sound assisted synthesis method. The effects of different drug: placebo ratios on the physical characteristics of the nanosponges as well as the drug content and in vitro drug release of the nanosponges were investigated. Particle size analysis and surface morphology of nanosponges were performed. The scanning and transmission electron microscopy of nanosponges showed that they were spongy in nature. The particle size was found to be in the range 46.37 - 97.23 nm out of which particle size of the optimized formulation was 51.79 nm and the drug content was found to 79.43 %. The optimized nanosponge formulations were selected for preparing nanosponge tablets for extended drug delivery by oral route. These tablets were prepared using xanthan gum and PVP K-30 and were evaluated by pre-compression and post-compression parameters. The nateglinide nanosponges tablet formulation were studied for different parameters using Design Expert Software. All formulations were evaluated for in vitro drug release analyzed according to various release kinetic models and it was found that it follows zero order release kinetics.
COGNITIVE ENHANCING ACTIVITY OF VITIS VINIFERA LINN IN RATS WITH EXPERIMENTALLY INDUCED AMNESIA AND ITS INFLUENCE ON CHOLINERGIC SYSTEM OF BRAIN
Authors: Patil K. S , Hadaginal R. V , Wadekar R. R ,   Department of Pharmacognosy and Phytochemistry, KLE College of Pharmacy, Kaher, Belagavi - 590 010, Karnataka, India b) Department of Pharmacognosy and Phytochemistry, Sinhgad Institute of Pharmaceutical Sciences, Lonavala - 410 401, Pune, Maharashtra, India.
Published: November 2021

The present study investigates the effect of ethanolic Vitis vinifera fruit extract on cognitive function in scopolamine, and electroshock induced amnesia in rats. To explore the potential effect, V. vinifera extract was screened by administrating dose (200 mg/kg) for 7 days using scopolamine-induced amnesia model. Cognition parameters were assessed using elevated plus maze and passive avoidance task method with Mentat as standard by using parameters of step down and transfer latency. Acetylcholinesterases enzyme level from brain homogenate was estimated on 7th day. V. vinifera extract (200 mg/kg) showed increase in escape latency (p<0.001) and time spent in target quadrant (p<0.05) while decrease in transfer latency (p<0.001) was observed in scopolamine induced amnesia. Further, pretreatment with V. vinifera (200 mg/kg) significantly reversed the behavioral impairment in scopolamine and electroconvulsive shock induced amnesia. Thus, that ethanolic fruit extract of V. vinifera possesses cognition enhancing property in scopolamine and electroshock induced amnesia models.
RP-HPLC AND HPTLC STABILITY INDICATING ASSAY METHODS FOR IVERMECTIN IN BULK AND TABLET DOSAGE FORM
Authors: Wani G. P , Jadhav S. B ,   Department of Quality Assurance Techniques, Modern College of Pharmacy, Pune - 411044, Maharashtra, India.
Published: November 2021

Simple, rapid, precise, accurate RP-HPLC and HPTLC methods have been developed and validated for ivermectin in bulk and its marketed formulation. RP-HPLC method for drug was achieved on Grace C18 (250 mm X 4.6 ID, Particle size; 5 μ) column using mobile phase acetonitrile: 10 mM phosphate buffer (95:05 v/v) pH adjusted to 3 with o-phosphoric acid. Detection of drug was done at 245 nm. The retention time was found to be 5.83 min. HPTLC method for ivermectin was accomplished on a precoated silica gel aluminium plate 60F-254 (CAMAG Linomat 5), using toluene: methanol: glacial acetic acid (8:2:0.1 v/v/v) as a mobile phase. The densitometric scanning was performed at 245 nm which showed Rf 0.46 for ivermectin. The stress testing of the drug individually was carried out under acidic, alkaline, oxidation, photo-stability and thermal degradation conditions. The proposed methods were successfully applied for the determination of drug in bulk and its marketed formulation.
SELF-SUFFICIENCY IN MANUFACTURE OF APIS AND INTERMEDIATES IS A NECESSITY FOR THE INDIAN PHARMACEUTICAL INDUSTRY
Authors:   Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai., Joshi Shreerang
Published: November 2021

Dear Reader, Active Pharmaceutical Ingredients (APIs) are key raw materials to produce pharmaceutical finished dosage forms like tablets, capsules, syrups, ointments etc. Swift growth in new innovations is prodding the interest for generic active pharmaceutical ingredients manufacturers worldwide with the expanded import of key starting materials (KSMs) and building blocks from the emerging markets. The focus of Indian pharmaceutical industry in last two decades has moved towards finished formulations, ignoring in-house manufacture of APIs to a considerable extent.
Urgence et opportunité: Confronter les crises liées à la santé, au climat et à la biodiversité en développant la reconnaissance et la protection des droits fonciers et des moyens de subsistance des peuples autochtones et des communautés locales
Authors:   Rights and Resources Initiative
Published: November 2021

Les opportunités pour un tel changement n’ont jamais été aussi claires et urgentes. En améliorant la collaboration avec les organisations autochtones et la société civile ainsi que leurs alliés, les gouvernements, le secteur privé et la communauté internationale pourraient débloquer le changement d’ampleur dont on a urgemment besoin. Alors que les gouvernements prennent des mesures pour relancer leurs économies suite à la pandémie de Covid-19, nombre d’entre eux reviennent sur les protections sociales et environnementales en place, tout en subventionnant les industries et les infrastructures, mettant en péril les droits et les moyens de subsistance des populations locales ainsi que les terres et les forêts qu’elles gèrent, ce qui rend les actions en faveur de la garantie de leurs droits d’autant plus essentielles et pressantes. Garantir les droits des populations locales et des femmes en particulier, et faire de leur rôle dans le développement durable une priorité représentent un des moyens les plus sûrs pour éradiquer la pauvreté, renforcer l’équité et apporter à tous une prospérité résiliente aux changements climatiques.
L’importance des territoires communautaires dans 24 pays pour le climat mondial
Authors:   Rights and Resources Initiative,   Woodwell Climate Research Center,   Rainforest Foundation US
Published: November 2021

Cette recherche rappelle opportunément l’importance mondiale des terres et territoires détenus par les communautés, leur importance pour la protection, la restauration et l’utilisation durable des forêts tropicales à travers le monde, ainsi que les lacunes critiques dans l’architecture du développement international qui ont jusqu’à présent sapé les progrès vers la reconnaissance légale de ces terres et territoires. Nos conclusions indiquent que les peuples autochtones, les peuples afro-descendants et les communautés locales détiennent et utilisent de manière coutumière au moins 958 millions d’hectares (mha) de terres dans les 24 pays examinés, mais qu’ils ont des droits légalement reconnus sur moins de la moitié de cette superficie (447 mha). On estime que leurs terres stockent au moins 253,5 gigatonnes de carbone (GtC), jouant ainsi un rôle vital dans le maintien des puits et réservoirs de gaz à effet de serre d’importance mondiale. Cependant, la majorité de ce carbone (52 %, soit 130,6 GtC) est stockée sur des terres et des territoires détenus par les communautés et qui n’ont pas encore été légalement reconnus.
Psychogene niet-epileptische aanvallen: verschillen in semiologie, maar ook in etiologie?
Authors: Dietze Christoph , Schelhaas Jurgen
Published: November 2021

In deze rubriek wordt het fenomeen ‘psychogene nietepileptische aanvallen’ (PNEA) belicht vanuit twee verschillende perspectieven. Er is een bijdrage over een diagnostiek programma dat bedoeld is om snel tot een adequate diagnose te komen, omdat het vroeg stellen van de diagnose de kans op een gunstige prognose verhoogt. In een tweede bijdrage gaat het om de kenmerken van PNEA bij patiënten met een verstandelijke beperking. In beide bijdragen staat de etiologie van PNEA ter discussie.
Epilepsie en het hart: hoe kunnen we SUDEP beter begrijpen en voorkomen?
Authors: Thijs Roland
Published: November 2021

Op 16 oktober 2019 promoveerde Marije van der Lende aan de Universiteit Leiden op haar proefschrift getiteld ‘Epilepsy and cardiac arrhythmias: understanding and preventing SUDEP’1. Van der Lende toont aan dat screening naar postictale ritmestoornissen bij hoog risico-groepen niet effectief is, maar dat het optimaliseren van het nachtelijk toezicht wel een effectief middel is om de kans op overlijden te verminderen.
O FARMACÊUTICO E SUA IMPORTÂNCIA NA ATENÇÃO BÁSICA DURANTE A EDUCAÇÃO EM SAÚDE: REVISÃO LITERÁRIA
Authors: Moura de Sousa Cássio
Published: November 2021

Introdução: O farmacêutico com base nas suas práticas clínicas tem a capacidade de ramificar uma série de informações técnicas que estão ligadas com alguns aspectos, tais como: dispensação, prescrição e ingestão dos fármacos. Objetivo: Identificar a importância do farmacêutico clínico na atenção básica durante as ações de educação em saúde. Metodologia: Trata-se de uma revisão bibliográfica, buscando os artigos na base de dados do Google Scholar e Scielo, com foco nos seguintes descritores: farmacêutico clínico; educação em saúde; atenção básica; automedicação. Diante ao contexto apresentado foi elaborado o seguinte questionamento: Qual o impacto da ausência do farmacêutico na equipe multiprofissional que trabalha na atenção básica ao paciente? Resultados e discussões: O serviço farmacêutico oferta uma quantidade significativa de ações que vão adequar uma melhor oferta dos serviços de saúde nos estabelecimentos públicos de atenção primária à saúde. As orientações podendo ser individuais ou grupais, incorpora os aspectos de dispensação e inserção da assistência e atenção farmacêutica. O Farmacêutico reitera-se de condutas e habilidades que o possibilita de promover o uso racional de medicamento nas ações em ações. Considerações finais: Foi perceptível que, as ações de educação em saúde são importantes para disponibilizar o conhecimento para a população, sendo que o farmacêutico clínico tem a habilidade de inserir suas condutas de atenção e assistência farmacêutica promovendo o uso racional do medicamento. Palavras-chave: Assistência farmacêutica; Farmacêutico clínico; Gestão em saúde.
Observed and simulated winter temperature over Gurudongmar area, North Sikkim, India
Authors: ARCHISMAN BARAT , P PARTH SARTHI , SUNNY KUMAR , PRAVEEN KUMAR , ASHUTOSH K SINHA
Published: November 2021

The global warming and its impact on the cryosphere is a matter of serious concern. The Sikkim and the Eastern Himalaya are a canvas of vivid landscapes and of different climate zones. The study of cryosphere needs more attention on long term climatic trends of surface air temperature. The Gurudongmar area is very much important because this area is surrounded by glaciers and as well as cold desert and TsoLhamo Lake nearby. The Gurudongmar lake (located at an altitude of 17,800 ft) has been studied by several researchers in the context of Glacial Lake Outburst Floods (GLOFs) and reported a high risk lake which is being largely affected by global warming and climate change. The present study is aimed to investigate the trend of temperature in recent past and in future time periods over the study area of Sikkim. The observed and model’s simulated gridded temperature data is considered to inkling of rising trend in winter months of December-January-February (DJF) over the study area. An increase in temperature is found for the future time period. This can be linked to the increasing hazard risk and change in local cryosphere environment.
Variability and trends of rainfall using non-parametric approaches: A case study of semi-arid area
Authors: JAYANTA DAS , TAPASH MANDAL , PIU SAHA , SUDIP KUMAR BHATTACHARYA
Published: November 2021

The analysis of variability and trends of rainfall can be used to assist better decision for climate risk and agricultural water management. This study makes an attempt to evaluate the trend and variability of annual, seasonal and monthly rainfall of 19 stations of Ajmer district, Rajasthan based on 44 year’s monthly rainfall data (1973-2016). Non-parametric Mann-Kendall (MK), Modified Mann-Kendall (mMK) and Spearman’s rho (SR) tests were used to achieve if there was an increasing or decreasing trend in the time series and the Sen’s slope (Q) estimator was applied to identify the quantity of the trend. From the results, it was found that annual and monsoon rainfall both showed an increasing trend at three stations, located in the central part and a decreasing trend at two stations, located in the north-western and south-western part of the study area. The magnitude of maximum increasing trends in both annual  and monsoon rainfall was observed at Goela (Q=+10.17 mm/year and+9.50 mm/year) while Jawaja (Q = - 6.76 mm/year and -5.21 mm/year) appeared with the maximum decreasing trends. On a monthly scale February showed an increasing trend at maximum number of stations (seven) and July showed a decreasing trend at maximum number of stations (seven). The information gathered from our study will help in future to estimate hydraulic procedures as well as to make sustainable water resource planning and management in this region.
Diagnostic study of diabatic heating and potential vorticity during a case of cyclogenesis
Authors: M K AL-MUTAIRI , H ABDEL BASSET
Published: November 2021

On 16-17 November, 2015, north and middle regions of Saudi Arabia were hit by a case of cyclogenesisassociated with heavy rainfall. This work presents a diagnostic study of this heavy rainfallcase based on the analysis of diabatic heating and potential vorticity. The synoptic analysis investigate that the important dynamical factors that causes this case are the northward extension of Red Sea Trough, anticyclone over the Arabian Peninsula, a travailing midlatitude upper trough, moisture transport pathways and strong upward motion arising from tropospheric instability. The calculation of diabatic heating by the thermodynamic equation illustrate that the contribution of vertical temperature advection and the adiabatic term are opposite to each other during the period of study. The largest contribution of the horizontal cold advection occurs during the first two days while the largest contribution of the horizontal warm advection occurs during the maximum development days. The dynamics of the studied case are also investigated in terms of isobaric Potential Vorticity. It is found that the location of the low-level Potential Vorticity anomaly and the Potential Vorticity generation estimates coincides with the heating region, which implies that condensation supports a large enough source to explain the existence of the low-level Potential Vorticity anomaly.
Statistical prediction of Sri Lankan rainfall during October to December
Authors: PABODINI KARUNAPALA , CHANGHYUN YOO
Published: November 2021

Sri Lanka receives most rainfall during October to December (OND). Here we construct multiple linear regression models to forecast the OND Sri Lankan rainfall during 1979-2012 for lead times of 1 and 2 months. Correlation analysis was used to examine the relationship between Sri Lankan OND rainfall and global sea surface temperature (SST) anomalies. Three independent predictors were identified through partial least square regression method which includes the southern Atlantic SST tendency, southern Pacific SST tendency and western Pacific and Maritime Continent SST tendency at two different lead times. Three-year-out cross validation concludes that the multiple linear regression models can produce forecast the OND rainfall forecast at correlation coefficient skill of 0.69 and 0.68 for the 1 and 2 month lead times respectively. The physical processes associated with these three predictors show that they contribute to increase in OND rainfall of Sri Lanka.