bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Disadvantaged Socioeconomic and Demographic Status on Overall Survival in Patients with Kaposi Sarcoma
Authors: Swedek Michelle , Zand Kamron , Silberstein Peter , Vardell Victoria
Published: September 2023

BACKGROUND: Kaposi sarcoma (KS) is a cutaneous and mucous membrane tumor caused by human/Kaposi sarcoma herpesvirus 8 (HHV-8), typically seen in immunocompromised patients, including those with HIV/AIDS. Patients from traditionally underserved and underrepresented (URM) populations have disparate survival outcomes across malignancies, however the effects of socioeconomic and demographic factors on survival have not been described on a large scale in KS.

METHODS: KS patients diagnosed from 2004-2017 were identified in the National Cancer Database (NCDB). Overall survival (OS) was analyzed using Kaplan Meier and adjusted Cox regression methods, and repeated in a propensity score matched cohort, where White patients were matched to Black patients 1:1 for demographic factors and comorbidities.

RESULTS: For the 4,034 identified patients, advanced age, Black race, HIV-positive status, and Charlson-Deyo score ≥1 were independently associated with decreased OS. Survival benefit was seen with Spanish/Hispanic ethnicity, private insurance, residence in areas of high educational attainment, and treatment at academic centers. Black patients had median survival of 99 months (95% confidence interval [CI] 73-124 months) compared to White patients (140 months, 95% CI 122-158 months) (p<0.001). Following propensity score matching, Black patients continued to have poorer OS compared to White patients (119 months versus 136 months, p=0.045).

CONCLUSION: We describe the impact of socioeconomic factors and race on survival in KS, finding significantly reduced survival in Black patients, which persisted after controlling for covariates. These results highlight the need for directed efforts promoting equitable outcomes for underrepresented minorities.
Self-regulation Perceptions of Dental Students
Authors: Hernandez Alleiah Madlangbayan , Pacaldo Ma. Lourdes Hamoy , Colina Trinette Chang , Aliola Nica Angela Forcadela , Blin Alexandria Ma. Louise Bincal , Coligado Justine Marice Montesines , Del Rio Adrian Philip Gamit , Magdaong Hiramia Nikka Janela , Cruz Rull Leah Anne Dela , Congzon Songco Karan Ferizz
Published: September 2023

Objective

Self-regulation refers to individuals’ capacity to govern and oversee their thoughts and actions, enabling them to adjust and react suitably to various things. This skill is important to be a lifelong learner. Dentistry is one profession where self-regulation can differentiate one from being called a “five-star doctor.” This study aims to evaluate the perceptions of self-regulation of students in a Philippine dental university.

Material and Methods

The research employed a descriptive cross-sectional research design using survey questionnaires. The Self-Regulation Formative Questionnaire (SRFQ) by Gaumer Erikson & Noonan (2018) consists of 22 items with four components: plan (5 items), monitor (6 items), control (6 items), and reflect (5 items). Participants’ responses were evaluated using a 5-point Likert scale. Twenty dental students from the same university were selected to answer the questionnaire as a pilot test. Subsequently, the questionnaire’s reliability was assessed, yielding a Cronbach's coefficient alpha value of 0.918.

Results

A total of 338 dental students (18% response rate) across the different year levels answered. Plan (75%) had the lowest percentage among the four components, and Reflect (82%) had the highest percentage. Overall, the students had good self-regulation (78.5%).

Conclusions

Dental students at the university have good self-regulation perceptions. Future studies can look into increasing the sample size and having respondents from other dental universities. Semi-structured interviews can also be done to understand the students’ responses better. Likewise, promoting self-regulation among students should be emphasized.
Emotional intelligence in neurosurgery: Mitigating burnout and enhancing performance
Authors: Alan Albert , Ennabe Michelle , Joshi Neil , Weinand Martin
Published: September 2023

Background:

This study underscores the high burnout rates among physicians, particularly surgical residents, attributing it to the demanding health-care ecosystem. It highlights the negative impacts of burnout, such as medical errors and increased health-care costs, while exploring the potential mitigating role of emotional intelligence (EI) and mindfulness. The research aimed to analyze the existing literature on EI in neurosurgery, focusing on its relationship with physician burnout and its potential role in healthcare leadership and residency training programs.

Methods:

A comprehensive literature review was conducted using multiple databases, including PubMed, OVID Embase, and OVID Medline, using the keywords “Emotional Intelligence” and “neurosurgery.” The search duration spanned from each database’s inception to June 2023.

Results:

The review highlighted various studies emphasizing the importance of integrating EI and mindfulness training into medical education and leadership, suggesting that a balance between technical competencies and interpersonal skills are critical. It identified personal integrity, effective communication, professional ethics, pursuit of excellence, relationship building, and critical thinking as key competencies for health-care leadership.

Conclusion:

EI and a growth mindset play a critical role in managing burnout, enhancing job satisfaction and performance, and promoting effective healthcare leadership. The review, however, acknowledges certain limitations such as small sample sizes, single-institution experiences, potential biases, and inconsistencies in burnout parameters and EI measurement tools. Despite these, it points toward potential areas for future investigation and highlights the importance of standardized EI measurement tools and robust quantitative assessment methods.
Cervicomedullary junction mature teratoma with pulmonary differentiation and diastematomyelia in an adult – A rare case
Authors: Peeters Sophie M. , Uhr Lauren , Chivukula Srinivas , McBride Duncan , Everson Richard , Duong Duc , Yang Isaac , Cornford Marcia , Mlikotic Anton , Yong William , Kim Won
Published: September 2023

Background:

Intradural extramedullary teratomas in the cervical or cervicomedullary region are rare in adults.

Case Description:

We report a symptomatic, mature teratoma at the cervicomedullary junction in a 52-year-old Hispanic female who also has a type I diastematomyelia in the thoracolumbar spine. The patient underwent surgical resection of the lesion with the resolution of presenting symptoms. Histopathology of the lesion revealed a mature cystic teratoma with pulmonary differentiation.

Conclusion:

We discuss the case along with a review of pertinent literature and considerations with regard to the diagnosis, etiology, prognosis, and management of this unusual pathology.
The Investigation of the Effect of 8-Week Walking Football Activity on Life Satisfaction and Heart Rate Variability in Elderly Men
Authors: ERDOĞAN YÜCE Ülküm , SAYGIN Özcan
Published: September 2023

The aim of the study was to examine the effect of walking football applied to elderly male sedentary individuals on life satisfaction and heart rate variability. 22 male volunteers whose physical activity level was determined by International Physical Activity Questionnaire (IPAQ) were included to this study. Volunteers were divided into 11 exercise groups and 11 control groups by random sampling. While the control group had no activity participation, the exercise group performed a 20-minute warm-up, they played 60 minutes of walking football, and they performed a 10-minute cool down. This was done 2 days a week across an 8-week period. In the study, the Life Satisfaction Scale (LSS) was used in the exercise and control groups, Heart Rate (HR), Heart Rate Variability (HRV), heart-mind coherence, maximum heart-mind coherence measurements were applied with the Heartmath-Inner Balance device. “Paired t test” was used for analyzing pretest-posttest differences in variables while "Independent t test" was used for analyzing differences between the groups. Findings show that there was a significant difference between the exercise group’s HRV, heart-mind coherence, maximum heart-mind coherence, and pre-post test measurements of the LSS results (p<0.05), although there was no significant difference in the HR variable (p>0.05). No significant difference was found between the pre-test and post-tests mean comparison of all variables of the control group (p>0.05). According to the results, it can be concluded that walking football has a positive effect on life satisfaction, HRV, heart-mind coherence, and maximum heart-mind coherence in older adults.
Cu-catalyzed Asymmetric Alkylation for Chiral Unnatural α-Substituted α-Amino Acids of Phallotoxins
Authors: Liu Guodu , Fan Lin , Li Jiashan , Yan Xinlong , Li Zongwei , Wang Yang , Pan Le
Published: September 2023

Asymmetric alkylation is one of the most important methods for synthesizing chiral unnatural α-substituted α-amino acids. Herein, We reported an asymmetric alkylation of tert-butyl glycinate Schiff base catalyzed by copper/(4S,2R)-tBu-Phosferrox catalysts. This catalyst shows high catalytic performance in the asymmetric alkylation at 1 mol % catalyst loading, giving the products with up to 95% yield and >99% ee. This method was successfully applied to synthesize a series of phallotoxins chiral unnatural α-substituted α-amino acids and the key intermediate, such as α-AAs-7 (4,5-OH-Leu) derivatives.
A machine learning framework for remaining useful lifetime prediction of li-ion batteries using diverse neural networks
Authors: Lee Junghwan , Sun Huanli , Liu Yongshan , Li Xue
Published: September 2023

Accurate prediction of the remaining useful life (RUL) of li-ion batteries (LIBs) is essential for enhancing the operational efficiency and safety of LIB-powered applications. It also facilitates improvements in the cell design process and the evolution of fast charging methodologies, thereby minimizing cycle testing time. While artificial neural networks (ANNs) have emerged as promising tools for this task, identifying the optimal architecture across diverse datasets and optimization strategies is non-trivial. To address this challenge, a machine learning framework is developed for a systematic evaluation of diverse ANN architectures. Utilizing just 30% of the training dataset from 124 li-ion batteries cycled under various charging policies, hyperparameter optimization is conducted within this framework. This ensures that each model is evaluated at its optimal configuration, facilitating a balanced comparison for RUL prediction tasks. Furthermore, the study examines the influence of varied cycle windows on model efficacy. Employing a stratified partitioning method highlights the importance of uniform dataset representation across different subsets. Notably, the top-performing model, using cycle-by-cycle features from just 40 cycles, achieves a mean absolute percentage error of 10.7%.
Sampling real-time atomic dynamics in metal nanoparticles by combining experiments, simulations, and machine learning
Authors: Cioni Matteo , Delle Piane Massimo , Polino Daniela , Rapetti Daniele , Crippa Martina , Arslan Irmak Ece , Van Aert Sandra , Bals Sara , Pavan Giovanni Maria
Published: September 2023

The atomic dynamics of metal nanoparticles (NPs), prominent already at low temperatures, is crucial for their properties but also challenging to elucidate. Recent advances in experimental approaches may provide atomically resolved snapshots of the structure of NPs in relevant regimes, but limitations in experimental data acquisition hinder the reconstruction of the atomic dynamics present within them. Molecular simulations -- typically starting from ideal/perfect NP structures -- allow tracking the motion of atoms over time, but suffer from limited sampling and provide results that, being dependent on the initial (putative) structure, are often only indicative. Here, combining state-of-the-art experimental and computational approaches, we demonstrate how it is possible to tackle the inherent limitations of both methods and resolve the atomistic dynamics present in metal NPs under realistic conditions. Annular dark-field scanning transmission electron microscopy (ADF-STEM) enables the acquisition of a time series of ten high-resolution images of an Au NP. Each image is taken at intervals of 0.6 seconds, providing data on a second timescale during the experimental sampling. These are used to reconstruct atomistic 3D structures of the real NP that are then used as starting configurations for ten independent molecular dynamics (MD) simulations. Unsupervised machine learning analysis of the data extracted from the MD trajectories using advanced structural and dynamical descriptors allows tracking and resolving the real-time atomic dynamics present within the NP under relevant conditions. This provides new perspectives into the realistic atomic dynamics within such NPs. We expect that such integrated experimental/computational approaches will become fundamental in various fields where the dynamics of NPs plays a key role, from catalysis to, e.g., nanoelectronics and biomedicine.
Femtosecond core-level spectroscopy reveals signatures of transient excited states in the photodissociation of Fe(CO)5
Authors: Tross Jan , Arias-Martinez Juan , Carter-Fenk Kevin , Cole-Filipiak Neil , Schrader Paul , McCaslin Laura , Head-Gordon Martin , Ramasesha Krupa
Published: September 2023

Excitation of iron pentacarbonyl (IP), a prototypical photocatalyst, at 266 nm causes sequential loss of two CO ligands in the gas phase, creating catalytically active, unsaturated iron carbonyls. Thus far, the electronic states involved in the dissociation have eluded experimental observation, hindering a comprehensive understanding of IP photochemistry. Using femtosecond extreme ultraviolet transient absorption spectroscopy near the Fe M2,3-edge, we present the first spectroscopic characterization of valence electronic dynamics during IP photodissociation. Informed by electronic structure calculations, we uncover the spectroscopic signatures of the intertwined structural and electronic evolution among the manifold of metal-centered excited states during first CO loss from IP on a 100-fs timescale. Furthermore, spectroscopic signals associated with the formation of Fe(CO)4 on its lowest singlet excited state and in structures fluctuating between C2v and C3v geometries, and its subsequent picosecond dissociation to Fe(CO)3 in the Cs geometry, are corroborated using quantum chemistry calculations.
Halogen Bonding and Mechanochemistry Combined: Synthesis, Characterization, and Application of N-Iodosaccharin Pyridine Complexes
Authors: Schumacher Christian , Truong Khai-Nghi , Ward Jas S. , Rajala Anssi , Lassila Elias , Bolm Carsten , Rissanen Kari
Published: September 2023

Halogen-bonded complexes are utilized across a myriad of synthetic chemistry fields, with halogen(I) complexes such as Barluenga’s reagent ubiquitous with respect to halogenation reactions. Especially the preparation of Barluenga’s reagent requieres the use of heavy metal salts and vast amounts of chlorinated solvents. In line with a more modern, environmentally-conscious ethos, halogen bonded adducts and a halogen(I) complex similar to Barluenga’s reagent based on N-iodosaccharin were prepared by mechanochemical processes for the first time. The general absence of solvents or the use of vanishingly small amounts of ethyl acetate in a liquid-assisted grinding approach during the mechanochemical preparations, enabled the homoleptic [(DMAP)–I–(DMAP)]+ iodine(I) complex to be synthesized. The as prepared mechanochemically materials were used in the iodination of antipyrine, demonstrating their potential use as surrogates for for Barluenga’s reagent in both solution and solid-state synthesis.
Strain-promoted cycloadditions in lipid bilayers triggered by liposome fusion
Authors: Jumeaux Coline , Spicer Christopher , Charchar Patrick , Howes Philip , Holme Margaret , Ma Li , Rose Nicholas , Rashid Harunur , Yarovsky Irene , Stevens Molly
Published: September 2023

Due to the variety of roles served by the cell membrane, its composition and structure are complex, making it difficult to study. Bioorthogonal reactions, such as the strain promoted azide–alkyne cycloaddition (SPAAC), are powerful tools for exploring the function of biomolecules in their native environment but have been largely unexplored within the context of lipid bilayers. Here, we developed a new approach to study the SPAAC reaction in liposomal membranes using azide- and strained alkyne-functionalized Förster resonance energy transfer (FRET) dye pairs. This study represents the first characterization of the SPAAC reaction between diffusing molecules inside liposomal membranes. Potential applications of this work include in situ bioorthogonal labeling of membrane proteins, improved understanding of membrane dynamics and fluidity, and the generation of new probes for biosensing assays.
The German Peasants' War, edited and trans. by T. Scott and B. Scribner - The Radical Reformation, edited and trans. by M. G. Baylor - The German Peasants' War and Anabaptist Community of Goods, by J. M. Stayer
Authors: Beish Clayton E.
Published: September 2023

The author in this one submission offers a review of three different books, which all seek to discuss the German Peasants' War of 1524-1525.
1. The German Peasants' War: A History in Documents. Eds. and trans. Tom Scott and Bob Scribner. New Jersey and London: Humanities  Press International, Inc., 1991. ISBN 0-391-03681-5. Pp. xvii+355.
2. The Radical Reformation. Ed. and trans. Michael G. Baylor. Cambridge: Cambridge University Press, 1991. ISBN 0-521-37073-6. Pp. xxxvii+295.
3. The German Peasants' War and Anabaptist Community of Goods. By James M. Stayer. Montreal: McGill-Queens University Press, 1991. ISBN 0-7735-0842-2. Pp. x+227.
Thomas Berry
Authors: Dalton Anne Marie
Published: September 2023

Anne Marie Dalton teaches in the Department of Religious Studies, at St. Mary’s University, Halifax, Nova Scotia. A long-time associate of the Holy Cross Centre on Ecology and Spirituality in PortBurnell, Ontario, Professor Dalton recently completed her doctoral dissertation, entitled Thomas Berry’s Religious Ecology in Light of Bernard Lonergan’s Theory of Emergent Possibility, at the Catholic University of America, Washington, D.C. Here, she comments on Thomas Berry’s contribution to the conversation between ecology and religion, as well as Berry’s preceding reflection on the religious implications of the Gaia Theory
Christian Perspectives on Religious Knowledge, edited by C. S. Evans and M. Westphal - Reasoned Faith, edited by E. Stump - Word and Spirit, by R. L. Hall
Authors: Barrigar Chris
Published: September 2023

The author in this one submission offers a review of three different books, which seek to discuss evangelical Christian philosophy and philosophical theology.

1. Christian Perspectives on Religious Knowledge. Ed. C. S. Evans and Merold Westphal. Grand Rapids: Eerdmans, 1993. ISBN 0-8028-0679-1. Pp.221.

2. ReasonedFaith. Ed. Eleanore Stump. Ithaca, N.Y.: Cornell University Press, 1993. ISBN 0-8014-9796-5. Pp. 357.

3. Word and Spirit: A Kierkegaardian Critique of the Modem Age. By R. L. Hall. Bloomington: Indiana Univ. Press, 1993. ISBN 0-253-32752-0. Pp. x+206.
Lonergan and Feminism, edited by C.S.W. Crysdale and Lonergan and Kant: Five Essays on Human Knowledge, by Giovanni B. Sala.
Authors: Kanaris Jim
Published: September 2023

The author in this one submission offers a review of two different books, which seek to discuss Bernard J.F. Lonergan.

1. Lonergan and Feminism. Ed. Cynthia S.W. Crysdale. Toronto: University of Toronto Press, 1994. ISBN 0-8020-7432-4. Pp. xiv+228.

2. Lonergan and Kant: Five Essays on Human Knowledge. By Giovanni B. Sala. Trans. Joseph Spoerl. Ed. RobertM. Doran. Toronto: University of Toronto Press, 1994. ISBN 0-8020-0429-6. Pp. xviii+178.
Protestant Opinion on the World Catechism of the Catholic Church
Authors: Pannenberg Wolfhart , Kanaris Jim
Published: September 2023

This article was originally published as “Eine evangelische Stellungnahme zum Weltkatechismus der katholischen Kirche,” Kerygma und Dogma 41 (1995): 2-12. Translated by Jim Kanaris, McGill University. With permission.
Jesus Between Jews and Christians
Authors: Moltmann Jürgen , Kline Scott
Published: September 2023

This article was originally published as “Jesus zwischen Juden und Christen,” Evangelische Theologie 1 (1995): 49-63. Translated by Scott Kline, McGill University. With permission.
"Fellow Travellers Along the Path"
Authors: Gelfand Jonah
Published: September 2023

In neo-Hasidism—which draws on traditional Hasidism while maintaining its position outside its sociological communities—the centrality of the idealised holy leader is nuanced, or outright rejected. In fact, by exploring its updated leadership models, it becomes clear that reformulating leadership was in fact one of the primary ways in which neo-Hasidism distinguished itself from traditional Hasidism. Whereas Hasidic leaders are traditionally charismatic by virtue of their exceptionalness, neo-Hasidic leaders are understood to be imperfect “fellow travelers along the path” who are charismatic by virtue of their relatability. And yet, despite this divergence, neo-Hasidism attempts to maintain its position within the Hasidic lineage.
DIGITAL TRANSFORMATION MANAGEMENT IN A COMMERCIAL ORGANIZATION: A CONCEPTUAL MODEL AND DIGITALIZATION IN PRACTICE
Authors: Веретёхин А.В.
Published: September 2023

Изучение и реализация цифровых трансформаций является популярным трендом, как в академических исследованиях, так и в деятельности коммерческих организаций. Настоящая работа нацелена на определение концептуальной модели управления цифровыми трансформациями компании на основе накопленного теоретического и практического опыта в диджитализации. Приведенные примеры демонстрируют дифференцированность целей и, соответственно, результатов цифровизации по экономическим отраслям и размерам коммерческих организаций. Полученные данные коррелируют с выводами других исследований. Предложенная модель содержит основные процессы/элементы, составляющие систему управления цифровыми трансформациями компании, и их взаимосвязи/взаимозависимости, учитывает драйверы диджитализации, а также риски, вызовы и угрозы цифровизации. В работе подчеркнуто, что в эффективной системе управления цифровыми трансформациями составляющие ее элементы должны выполняться синхронно и слаженно. Организация такого сложного процесса в значительной мере зависит от умения и навыков руководителей. По мнению автора, представленная в статье информация может помочь коммерческим организациям выстраивать практическое управление своими цифровыми трансформациями обоснованно и корректно.

Digital transformations are a modern trend for both commercial organizations and academic works. This paper aims at defining a conceptual model for management of a company digital transformation, based on the accumulated theoretical and practical experience in digitalization. The given examples demonstrate the differentiation of the goals and, consequently, the results of digitalization by economic sectors and the size of commercial organizations, which correlates with the data of other studies. The proposed model contains the main processes/elements that make up a company's digital transformation management system and their relationships/interdependencies, takes into account the drivers of digitalization, as well as the risks, challenges and threats of digitalization. The paper emphasizes that in an effective digital transformation management system, its constituent elements must be performed synchronously and coherently. The organization of such a complex process depends entirely on the ability and skills of managers. In the author's opinion, the information presented in the article helps commercial organizations to manage their digital transformations in a reasonable and correct way.
FACTORS OF SOCIO-ECONOMIC DIFFERENTIATION OF THE CITIES AND TOWNS IN THE TVER REGION
Authors: Щукина А.С.
Published: September 2023

Актуальность исследования социально-экономических процессов в городах и ПГТ Тверской области, определения степени устойчивости опорного каркаса расселения региона определяется нарастающей асимметрией в их развитии, прежде всего концентрацией населения и экономической активности в региональном центре. Цель исследования – анализ факторов, определяющих неравномерность социально-экономического развития городов и ПГТ Тверской области. Выявлены и проанализированы факторы неравномерного развития городов и ПГТ Тверской области, среди них сжатие экономической базы, неудовлетворенность условиями труда и, как следствие, миграционный отток и сокращение численности населения, Ситуацию усугубляют особенности конфигурации территории области и значительная удаленность большинства городов и ПГТ от регионального центра. Социально-экономическое неблагополучие проявляется в уровне их благоустройства. Дана сравнительная оценка отдельных аспектов качества городской среды – уровня комфортности жилья и состояния улично-дорожной сети.

The relevance of the study of socio-economic processes in cities and urban areas of the Tver region, the determination of the degree of stability of the reference framework for resettlement of the region is determined by the growing asymmetry in their development, primarily the concentration of the population and economic activity in the regional center. Purpose of the study. Analysis of factors determining the unevenness of the socio-economic development of cities and urban areas of the Tver region. Study results. Factors of uneven development of cities and urban areas of the Tver region were identified and analyzed. Among them are the contraction of the economic base, dissatisfaction with working conditions and, as a result, migration outflow and population decline. The situation is aggravated by the peculiarities of the configuration of the region's territory and the significant remoteness of most cities and urban areas from the regional center. Socio-economic disadvantage is manifested in the level of their improvement. A comparative assessment of certain aspects of the quality of the urban environment is given – the level of comfort of housing and the state of the road network.
THE FEATURES OF THE FUNCTIONING OF THE PUBLIC-PRIVATE PARTNERSHIP MECHANISM IN THE RUSSIAN FEDERATION
Authors: Виноградова Е.К. , Толкаченко Г.Л.
Published: September 2023

В настоящее время экономическая система страны проходит через этапы структурных преобразований, направленных на стабилизацию экономического развития, посредством достижения национальных целей, задач и в целом позволяющих формировать новую экономическую модель страны, направленную на улучшение качества жизни людей. Одним из таких механизмов, позволяющих достигать поставленные цели и задачи, является государственно-частное партнерство (ГЧП), в настоящее время успешно реализуемое в ряде европейских и западных стран. Однако в нашей стране его использование не является столь признанным, и на это существуют определенные причины. Цель статьи заключается в определении и раскрытии основополагающего фактора, способствующего формированию и дальнейшему развитию данного механизма в России – созданию институциональной среды ГЧП. Научная новизна заключается в разработке авторской схемы построения системы институциональной среды ГЧП в РФ, включающей формальные и неформальные институты, характеризующие особенности его функционирования.

The economic system of the country goes through the stages of structural transformation, which, first of all, will be aimed at stabilizing economic development, and secondly, at creating conceptually new structural transformations that can achieve national goals, objectives and, in general, form a new economic model of the country. The main goal of this model will be to maximize the satisfaction of a person's unique needs, stabilizing and improving the well-being of the people - improving the quality of life. One mechanism that solves this problem is public-private partnership (PPP). The analysis of journalistic publications made it possible to draw a preliminary conclusion that for the state, and for business, and for the population of our country as a whole, there are factors of attractiveness of using PPP mechanisms, but its institutional environment has not yet been finally formed and there are reasons (features) for this, which are disclosed in this article.
POLITICAL ECONOMY – FROM THE PAST TO THE FUTURE THROUGH THE SCIENTIFIC HERITAGEOF E.V. BOYARSKY
Authors: Смирнов А.В.
Published: September 2023

Цель статьи – ознакомить читателей, в первую очередь современную молодежь, которой предстоит взять груз испытаний в нашей стране и продолжить эстафету созидательных дел старшего поколения, со взглядами основателя кафедры политической экономии Калининского государственного университета, а ныне кафедры экономической теории Тверского государственного университета Ефима Владимировича Боярского. Ефим Владимирович заложил фундамент экономической науки в Тверском крае, особый интерес вызывают его работы, написанные им в эпоху глобальных потрясений нашей Родины в 20–30-е гг. XX-го века. Для поиска решения текущих проблем, стоящих перед нашим обществом, читателям предложено прочувствовать сквозь призму истории процесс формирования смыслов (интеллектуальные конструкции), развивающихся в молодой академической среде 20–30-х гг. XX века, во вновь формирующемся мире и протянуть временную нить длиною в 100 лет от Е.В. Боярского к настоящему времени.

The purpose of the article is to familiarize the student community with the views and materials of the founder of the Department of Political Economy (Economic Theory) of TvSU in the era of global upheavals of the 20–30s of the XX century. Disputes about the fate of Russia, its vocation in the world, in our opinion, are not outdated and continue to live in new forms. Misunderstanding of the meanings on the basis of which our country exists leads to sad, sometimes destructive consequences. To understand the state of the current time and possible solutions to the problems facing our society, we examined a similar process using the example of the scientific works of the founder of the Department of Political Economy of TvSU, E.V. Boyarsky, and invited contemporaries to feel how meanings were formed in the newly emerging world in the 20 – 30 s of the XX century in a young academic environment (environment "red professorship") and stretch a temporary thread from it to the present.
TROPHIC STRUCTURE OF MACROMYCETE FUNGI IN THE LIKHOSLAVL MUNICIPAL DISTRICT OF THE TVER REGION
Authors: Курочкин С.А. , Плисова А.С.
Published: September 2023

В данной работе представлены результаты изучения трофических групп у грибов-макромицетов, которые были выявлены авторами на территории в окрестности деревни Барановка Лихославльского муниципального округа Тверской области. Список грибов макромицетов составил 161 вид из 35 семейств. Проведен анализ трофической структуры. Выделено 13 трофических групп. Отмечено доминирование микоризообразователей (46,58%) относительно высокая доля сапротрофов: на подстилке (21,74%), на древесине (19.25%), на гумусе (15.53%).

Here we present the results of a study of trophic groups in macromycete fungi, which were identified in the vicinity of the village of Baranovka, Likhoslavl Municipal District, Tver Region. The list of macromycete fungi includes 161 species from 35 families. Thirteen trophic groups have been identified. The dominance of mycorrhiza-forming organisms (46.58%), a relatively high proportion of saprotrophs was noted with 21.74% on the litter, 19.25% on wood, and 15.53% on humus.
COMPARATIVE ANALYSIS OF METHODS FOR PRODUCING EGG OIL AND ITS FATTY ACID COMPOSITION
Authors: Сандакова С.Л. , Ревякин А.О. , Мотина Н.В.
Published: September 2023

Куриный желток состоит на 31,2% из яичного масла. Показатель жирнокислотного состава этого желтка зависит от сбалансированности и полноценности питания самой курицы. Яичное масло богато омега-3 и омега-6 жирными кислотами, что делает его крайне ценным. Патенты на получение яичного масла в основном описывают методы физического воздействия и химической экстракции. При таком способе получения есть обязательная процедура последующего извлечения из него самого экстрагирующего агента. Масло, полученное такими способами не универсально в применении и дорогостояще. В основе работ по изучению и получению такого масла должны быть возможности его применения. Использование желткового масла в народной медицине Китая касается именно терапии и применение в дерматологии и косметологии. Впервые использование яичного масла было зафиксировано в «Теории лечебных свойств» династии Тан. В древней Китайской медицинской книге, которая в переводе называется «Compendium of material medical» отмечено, что это не яркое и прозрачное экстрагированное масло, а именно горькое, коричневое с черными липидами масло. Оно не содержат холестерина, и обладает чудесной пользой для организма. Поэтому изучение и получение именно темного масла, и разработка перспектив его применения является для нас актуальной задачей.

Chicken yolk consists of 31.2% egg oil. The indicator of the fatty acid composition of this yolk depends on the feeding of the chicken itself; therefore, the quantitative ratio of the qualitative composition of these indicators in different breeds of domestic chicken and broiler crosses is not a stable phenomenon. Egg oil is rich in omega-3 and omega-6 fatty acids and is close to the fatty acid profile of human breast milk, making this raw material extremely valuable. These are mainly methods of physical influence and chemical extraction. All known methods of separating egg oil from egg yolks are based on the extraction of raw or dried egg yolks with a fatdissolving extracting agent, filtering the resulting extract and removing the extracting agent from it. The oil obtained by such methods is not universally applicable and expensive. The work on the study and production of such an oil should be based on its application. The use of yolk oil in Chinese folk medicine concerns precisely therapy and even dermatology and cosmetology. All methods of application are very ancient. It was first recorded in the "Theory of healing properties" of the Tang dynasty. In the ancient Chinese medical, book "Compendium of material medical», it is noted that this is not a bright and transparent extracted oil, but rather a bitter, brown oil with black lipids. They do not contain cholesterol, and have miraculous benefits for the body. Therefore, obtaining just dark oil and the development of prospects for its use is an urgent problem.
Troska jako katalizator oporu. Przypadek pracowników niezrzeszonych
Authors: Gitkiewicz Olga
Published: September 2023

Troska w socjologii, zwłaszcza socjologii pracy, to przede wszystkim badania pracy opiekuńczej. W niniejszym artykule staram się wyjść poza tę perspektywę. Troska jest dla mnie kategorią centralną, definiuję ją jako praktykę i jako relację osób związanych poprzez miejsce pracy, które okazują sobie wsparcie.

W tekście przedstawiam współczesne koncepcje troski, analityczny potencjał tej kategorii oraz definicje użyteczne w badaniu miejsca pracy. Podstawą empiryczną zawartych w tekście rozważań jest analiza wywiadów przeprowadzonych z nieuzwiązkowionymi pracownikami i pracownicami małych i oraz średnich przedsiębiorstw usługowych, które okazują się trudnymi miejscami pracy. W części analitycznej zostaną ukazane praktyki, które identyfikuję jako pracowniczą troskę, i które są ukierunkowane nie tylko na dawanie emocjonalnego wsparcia, ale również na aktywizowanie pracowniczego oporu. Twierdzę tym samym, że troska i opór w miejscu pracy są ze sobą powiązane, a celem artykułu jest wielowymiarowe spojrzenie na ten związek.
Laboratoria walki klas. O stosunkach klasowych w platformach pracy na żądanie
Authors: Mika Bartosz
Published: September 2023

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Budget programmes as a tool for ensuring self-sufficiency of territorial communities and an object of accounting
Authors: Denysovets Y.M.
Published: September 2023

The article analyses the state and sources of formation of local budgets of territorial communities of Ukraine. It is established that the development of territorial communities, despite their significant own potential, largely depends on transfers from the state budget.

The main substantive characteristic of a self-sufficient community is defined and it is proposed to calculate indicators for assessing its status at two levels, which are formed by own revenues and transfers.

The main instrument for creating an effective and efficient mechanism for the use of funds in a community is budget programmes. In order for budget programmes to fulfil their goals and objectives and achieve the expected results, it is important to classify them according to the features that characterise expenditures that address the needs of the community. The study allowed us to identify 10 classification characteristics of budget programmes, which are the key to the scientifically sound development of financial and management accounting in budgetary institutions.

In the context of management accounting, budget programmes should be viewed as centres of responsibility for expenditures and their results. Under such conditions, the main provisions of the programme-targeted method of managing budget funds will be fully used.

However, in order to introduce management accounting of budget programmes, it is necessary to create information screens to display business transactions on the formation of expenses at the expense of budgetary funds. Taking into account the specifics of the chart of accounts in the public sector, the author substantiates the possibility of keeping records of expenses in the context of budget programmes and the formation of their performance indicators on account 16 «Production» or on a new account with a free code 19 «Expenses for the implementation of budget programmes».
Ethical responsibility of professional accountants in the context of supporting sustainable development goals
Authors: Tarasevych H.P. , Chyzhevska L.V.
Published: September 2023

The article discusses the impact of professional accountants’ adherence to fundamental principles of ethics, their impact on supporting sustainable development, and responsibility for violations of ethical principles. The issue of ethical responsibility of professional accountants in the context of supporting the goals of sustainable development is one of the primary tasks and requires a solution. Modern conditions also require an appropriate response to changes in ethical codes of professional accountants in order to meet new challenges. In order to always have up-to-date knowledge and skills in a certain field, it is necessary to constantly monitor all changes that occur in regulatory legislation. Since the accounting profession has a responsibility to act in the public interest, accountants are required to act transparently to ensure proper compliance with both legal and ethical requirements, and to contribute to the sustainable development of both business and society in general. Traditionally, professionalism includes, among other things, commitment to the public interest; a complete set of knowledge supported by a strict education system; independence and professional code of conduct.
ТЕХНІКО-ЕКОНОМІЧНІ ПОКАЗНИКИ ОТРИМАННЯ ЛІГАТУРИ ПРИЦЕНЗІЙНИХ СПЛАВІВ НА ОСНОВІ ТЕХНОГЕНИХ ВІДХОДІВ
Authors: Григор’єв Станіслав Михайлович , Скачков Віктор Олексійович , Бережна Ольга Русланівна , Варченко Дмитро Анатолійович , Гнатишак Руслан Васильович
Published: September 2023

Для розробки шихти і складу Ni – Mo лігатури для виробництва і використання її у прецизійних сплавах досліджено фізико-хімічної властивості вихідних інгредієнтів, в тому числі і техногенних відходів. Розроблено склад лігатури, кількісні і якісні показники шихтових складових та технологічні умови нового легувального і розкислю вального матеріалу для прецизійних сплавів. Вперше в роботі представлені техніко-економічної показники використання техногенних відходів, якої не знаходили місце в металургійній промисловості спеціальних сталей і сплавів якості вторинної сировини. У промислових умовах проведено активний експеримент із зміною параметрів у межах. Зміст елементів у лігатурі змінювалося не більше, мас.%: нікелю 53,0–91,6; молібдену 2,8–18,4; марганцю 1,0–7,8; кремнію 0,3–5,6; заліза 4,3–15,2. Лігатура отримана в електропечі з основним футеруванням із застосуванням відходів сплавів на основі нікелю (прецизійного сплаву 79 НМ); окалини та шліфувального пилу, а також феросиліція ФС65, металевого марганцю МР‑1, технічного закису нікелю та гідрометалургійного молібденового концентрату. По уточненій методиці виконані відповідні розрахунки економічної ефективності утилізації Ni та Mo із техногенних відходів з урахуванням факторів, які набули розвитку в дійсній роботі. З метою досягнення оптимальних показників Ni – Mo з урахуванням комплексного впливу складу шихти на зниження собівартості переділу виплавки лігатури при моделюванні використовували регресійний аналіз. Узагальнюючим методом найменших квадратів на основі результатів промислових випробувань розроблена математична модель залежності економічних показників виплавки лігатури від вмісту легувальних елементів в лігатурі і технологічних показників. Це дозволило оптимізувати основні техніко-економічні залежності показників виробництва і використання Ni – Mo лігатури і значно підвищили їх ефективність.
РОЗРАХУНОК ТА ВИКОРИСТАННЯ КОТЛА-УТИЛІЗАТОРА У ВІТЧИЗНЯНІЙ МЕТАЛУРГІЇ ДЛЯ ПІДВИЩЕННЯ ЕФЕКТИВНОСТІ ПРОЦЕСІВ ТЕПЛОМАСООБМІНУ
Authors: Ільїн Сергій Віталійович , Погребна Юлія Сергіївна , Волков Єгор Володимирович , Карпенко Ганна Володимирівна
Published: September 2023

Раціональне використання паливно-енергетичних ресурсів, охорона навколишнього середовища відносяться до найважливіших проблем, що стоять перед людством. Високотемпературні процеси здійснюються у технологічних печах (металургійна, хімічна, нафтохімічна та інші галузі промисловості) за надзвичайно низького коефіцієнта використання органічного палива (20–40 %). Як результат ці виробництва викидають гази, температури яких перевищують іноді 1000 °C, токсичні речовини, дрібнодисперсний пил застосовуваної сировини та інші технологічні відходи, які забруднюють довкілля. Тому переробка та експлуатація відходів цих технологічних процесів є важливим завданням, виконання якого можливе на основі використання їх теплоти в котлах-утилізаторах або при спільній організації технологічного та енергетичного процесів в енерготехнологічних агрегатах. В статті представлено розрахунок котла-утилізатора, зведений у таблиці. Вибір оптимальних параметрів обладнання для кращого введення в експлуатацію без порушення технологічного процесу. В цілому дане обладнання має ряд переваг. А саме: простота його виконання, надійність в експлуатації, надійність роботи теплопередаючих елементів та висока ефективність процесів тепломасообміну, відносно малий гідравлічний опір, автономність і т. д. Використання вторинних енергоресурсів будь-яких видів в технологічних процесах пов’язане з підвищенням енергетичної ефективності, поліпшенням показників технологічних процесів і умов навколишнього середовища, тобто в єдиний процес зведені технологія і енергетика. Введення котла-утилізатора може істотно підвищити економічний ефект виробництва. Звільнену і отриману теплову енергію можна використовувати в якості перетворень в механіку, що дозволяє забезпечити автономність джерел енергії котлівутилізаторів.
Investigating the Role of Hippo Signaling Effector Protein YAP1 in the First Lineage Decision in Cattle Embryos
Authors:   , Dempster Kate
Published: September 2023

In vitro embryo production (IVP) has provided insights into early embryogenesis in the murine model, however our current understanding of embryogenesis in the bovine model is less complete. A crucial event in mammalian embryonic development is the first lineage specification, where the trophoblast (TB) and the inner cell mass (ICM) are formed. The formation of these distinct cellular lineages is governed by various cell signaling pathways, foremost among which is the Hippo signaling pathway. The Yes-associated protein 1 (YAP1) is a key effector of Hippo signaling and has been shown to be involved in the regulation of mouse cellular lineage fates. The manipulation of this molecular pathway will provide information on whether Hippo pathway-dependent or Hippo pathway-independent mechanisms are involved in the regulation of YAP1 localization and first lineage specification in cattle.

Currently, there is limited research regarding the role of Hippo signaling in the establishment of polarity in the bovine embryo. We found that upon RHOA inhibition via C3-transferase, polarity factors EZRIN and AMOT exhibit reduced expression at the apical domain. Although it was not determined whether impaired embryo compaction and polarization was associated with YAP1 activity, it is evident that RHOA signaling is required for normal bovine compaction.

This research illustrated that RHOA facilitates YAP1 intracellular distribution in bovine embryos as RHOA inhibition activates the Hippo signaling pathway and shuts down YAP1 activity. In contrast, LATS1/2 inhibition via Lats-ln-1 resulted in unexpected YAP1 expression, hence the exact involvement of LATS1/2 in YAP1 nuclear localisation remains unclear. Furthermore, we concluded that RHOA and thereby YAP1 activity is involved in blastocyst formation as inhibition of RHOA may impair cell properties required for development beyond the morula stage.

Bovine embryos have a longer pre-implantation period than murine embryos, emphasizing that a complex network of mechanisms are involved in the establishment of the first lineages. In this thesis, RHOA inhibition was not linked to the second lineage determination and its role in the first lineage commitment was negligible. We showed that YAP1 modulation via LATS inhibition may impact the localisation and expression of first lineage markers. However, misexpression of 2 lineage markers in LATS1/2 inhibited blastocysts suggests that Lats-ln-1 may have a deleterious effect on bovine embryos.

In summary, we proved that Hippo signaling is involved in cell polarity and blastocyst establishment in the bovine embryo. Due to the complexity of bovine blastocyst formation, it is apparent that an extensive network of effectors and mechanistic pathways must also be involved in lineage determination independent of the Hippo signaling pathway.
Anais do I Simpósio de Pesquisa e Inovação Tecnológica do HU-UFPI/EBSERH
Authors: HU-UFPI Hospital Universitário
Published: September 2023

O I Simpósio de Pesquisa e Inovação Tecnológica do HU-UFPI/EBSERH oportunizou a discussão sobre desenvolvimento científico e tecnológico no âmbito do HU-UFPI e UFPI e assim contribuir para a formação de alunos, residentes e colaboradores nessas temáticas corroborando assim com a visão deste nosocômio que é: "Impulsionar as atividades acadêmicas nas áreas de ensino, pesquisa e extensão, em consonância com as diretrizes institucionais da Universidade Federal do Piauí, apoiado na assistência à saúde pública de média e alta complexidade, de forma sustentável, transparente e inovadora, com elevado padrão de qualidade e máxima abrangência, com o intuito de promover a formação de profissionais com notável saber e excelência técnica no Estado do Piauí". O objetivo geral do evento foi fomentar o desenvolvimento científico e tecnológico permitindo o compartilhamento de experiências desenvolvidas nas mais diversas áreas do conhecimento possibilitando assim o diálogo e a discussão sobre pesquisas institucionais com a comunidade acadêmica.