bluuebunny/crossref_metadata_2025 huggingface dataset:
Pesquisa em Cuidado Paliativo no Brasil
Authors: Oliveira Livia Costa de
Published: June 2021

Atualmente, a pesquisa relatada na literatura científica no âmbito do cuidado paliativo no Brasil é demasiadamente limitada. Há um estigma cultural que iguala o cuidado paliativo ao cuidado de fim de vida, associado a imensas lacunas no campo do ensino e pesquisa que precisam ser preenchidas para contrapor a  essa questão. Portanto, é necessário que o desenvolvimento científico seja capaz de responder a aspectos conflitantes de cada um desses momentos, não só relacionados ao cuidado de fim de vida, período em que o  delineamento dos estudos pode ainda envolver questões de natureza ética complexas. Faz-se necessária a condução de pesquisas metodologicamente rigorosas, capazes de fornecer evidências de alta qualidade, propiciando o embasamento para a construção de protocolos capazes de conduzir a melhoria da prática  clínica ao cuidado paliativo, em todas as suas fases, bem como a formulação de políticas de saúde  relacionadas à temática.
ECOLOGICAL FOOTPRINT IN RESEARCHES OF ECOLOGICAL COUNTRY/REGIONAL CONVERGENCE: CRITICAL LITERATIRE REVIEW
Authors: Verstiak Andrii
Published: June 2021

The paper investigates indicators to be used to assessing the ecological convergence of countries/regions. There are numerous empirical studies in the scientific literature on the convergence of environmental and economic indicators, which are considered as the key goal of efforts to reduce emissions in different countries. The convergence of these indicators is the basis of many scientific schools of climate change researches. When countries converge, they can work together to address environmental threats and agree on their emission reduction commitments. To this end, CO2 emissions are used in researches, but a critical analysis of scientific sources has shown that researchers are inclined to use the ecological footprint, which is a complex cumulative indicator. It is noted that the CO2 emission indicator reflects only part of the cumulative effects that result from extensive energy consumption [11]. In addition to CO2 emissions, the use of resources such as forests, soils, oil, gas and mining reserves also has a significant impact on the environment. For example, in developed countries there is a decrease in the number of specific pollutants per unit of output, which has been achieved by technological progress and the implementation of strict environmental legislation; however, wastewater pollution has shifted from nitrogen and sulfur oxides to solid waste, so total waste remains high and waste per capita may even remain stable. The above indicates that specific indicators of negative impact on the environment, including CO2 emissions, need to be supplemented with comprehensive cumulative indicators, which is the purpose of this article. It was found that the indicator of ecological footprint is a more adequate indicator, as it includes a set of variables of environmental pollution. In this regard, it is concluded that the use of ecological footprint in the study of ecological and economic convergence of countries/regions is relevant: based on the results of convergence tests of ecological footprint, country leaders can decide to conduct a common or differentiated environmental and economic policy to decrease environmental pollution.
MODERN BUSINESS METRICS FOR EVALUATION OF EFFICIENCY OF MARKETING MEASURES
Authors: Panchyshyn Taras , Prokopovych-Pavlyuk Iryna
Published: June 2021

The article substantiates the need to use marketing analytics when planning marketing campaigns with the involvement of the maximum possible number of communication channels in a time dimension. The area of research is the search for effective business metrics used to assess the effectiveness of the implementation of marketing activities.
The results of the study showed that at the present stage of development of analytical capabilities, traditional methods of selecting business metrics are changing and depend on the scope of business and the competitive environment, the channels of interaction with customers and their behavior. When choosing the correct metrics, analyst should take into account all the sources of the information, also who will use this data to draw conclusions and make business decisions.
Thus, to analyze the performance of the website, we should determine the number of visits, conversion and retention rates. We can evaluate effectiveness of email campaigns by the proportion of open emails, the number of clicks, and return on investment. In the case of paid advertising analysts should estimate the quantity and cost of clicks, the number and value of potential customers.
For effective management of marketing activities, it is advisable to use the following business metrics: the cost of attracting one consumer, the cost of the consumer throughout his/her life as a consumer of the company's products or services, the average monthly income per consumer and the proportion of users who performed the targeted action.
The primary indicators for calculating business metrics are the company's revenue and expenses. To obtain a reliable value for a business metric, one should take into account all types of expenses associated with product promotion — salaries for specialists in advertising, the cost of photos and videos for advertising posts, designer’s work, payment for writing advertising texts, communication costs, and others.
The sequence of metric selection according to one approach corresponds to the traditional conversion funnel. However, nowadays for the most services a high level of new user engagement does not necessarily mean success. Thus, better sequence of metrics is as follows: retention, activation, referral, revenue, acquisition.
DETERMINACIÓN DE AFLATOXINAS TOTALES (AFs) Y AFB1 EN DULCES TIPO “MAZAPÁN” DE CACAHUATE Y NUEZ COMERCIALIZADOS EN LA ZONA METROPOLITANA DE GUADALAJARA, JALISCO
Authors:   UNIVERSIDAD DE GUADALAJARA, Jiménez-Ortega Luis A , Cuevas-Sánchez Bárbara Y , Patricio Martínez Severiano , Albarrán Rodríguez Esther , González Zamora Luis F. , Reyes Velázquez Waldina P
Published: June 2021

Las aflatoxinas (AFs) son micotoxinas asociadas con diversos trastornos en la salud humana, destacando efectos de inmunosupresión, mutagénicos, cancerígenos y teratogénicos. La contaminación de alimentos con AFs está ampliamente documentada a nivel mundial, los reportes indican altos niveles en cereales, frutos secos y cacahuate. El propósito del estudio fue detectar la presencia de AFs totales y AFB1 en 66 muestras de dulces tipo “mazapán” de diferentes marcas y lotes, 54 correspondieron al dulce de cacahuate y 12 muestras a los dulces de almendras y nuez. Las técnicas analíticas utilizadas fueron: Cromatografía de inmunoafinidad e Inmunoensayo enzimático (ELISA). Los resultados mostraron contaminación con AFs en el 100% de las muestras del “mazapán” de cacahuate y nuez, la mayor concentración se observó en el dulce a base de cacahuate (9.25 mg/kg) diferente estadísticamente (P< 0.05) al nivel promedio del dulce de nuez (1.17 mg/kg). Los niveles promedio de AFB1 detectados en las muestras de 2 marcas de “mazapán” de cacahuate (niveles promedio: 19.8 mg/kg -144.17 mg/kg) superaron el límite establecido por la legislación internacional para los países exportadores de productos alimenticios a base de cacahuate (15 mg/kg). En México no existe reglamentación que establezca el límite máximo permitido para AFs y AFB1 en cacahuate, frutos secos y productos derivados por lo que es necesario la revisión de la Normatividad para reducir el riesgo de exposición en la población.
TRABAJO INTERCENTROS PARA LA DEFINICIÓN DE LA NUEVA ESTRUCTURA CURRICULAR DEL PLAN DE ESTUDIOS DE LA LICENCIATURA EN BIOLOGÍA: UNA VISIÓN POR COMPETENCIAS
Authors:   UNIVERSIDAD DE GUADALAJARA, Quiroz Rocha Georgina Adriana , Kelly Gutiérrez Liza Danielle , Amparán Salido Rosio Teresita , Domínguez Arias Rosa María , López López Cinthya Araceli , Medina Rosas Pedro , Muñoz Urias Alejandro , Gudiño Cabrera Graciela
Published: June 2021

This document offers an approach to the collegiate work carried out for the curricular restructuring of the Undergraduate Educational Program for the Bachelor of Biology at the University of Guadalajara. It presents the main elements of analysis and curricular definition that gave structure to the opinion proposal that is currently in force. Finally, it provides some reflections on the challenges involved in collegiate work between curricular committees called “inter-centers”.
Passive design strategies for medium-format retail buildings in Toronto toward NZE
Using Ecotect® Analysis 2011, with a case-study of a retail building in Toronto, ON
Authors: Shukor Issam A.
Published: June 2021

This paper studied passive design strategies available for medium-format retail buildings in Toronto. An existing retail building, designed by the researcher and built in 2014, was chosen as a case study. A framework of four models to show incremental improvements was created and multiple passive design strategies were applied to each model.
The framework targeted four energy goals. Each goal represented a level of higher efficiency using Energy Use Intensity (EUI). Each of the four design models was simulated using Ecotect® and all results documented and analyzed. At the end of last model’s analysis, an architectural design project to exhibit design strategies was created.
There are perhaps two significant points that the study has achieved. First point was the identification of key passive strategies that can be implemented in retail buildings in Toronto. The second was the methodology by which incremental improvements with pre-set energy targets can be followed with validated results.
Adaptive Methods For Stochastic Simulation Of Biochemical Systems
Authors: Teslya Alexandra
Published: June 2021

Computational and Systems Biology are recently experiencing a rapid development. Mathematical modeling is a key tool in analyzing critical biological processes in cells and living organisms. In particular, stochastic models are essential to accurately describe the biochemical processes in the cell. However, stochastic models are computationally much more challenging than the traditional deterministic models. Also, the sheer scale of biological processes makes efficiency of the simulation a key issue. In this thesis we study the numerical solution of a continuous stochastic model of biochemical systems, the Chemical Langevin Equation.

We propose an adaptive step-size method for the Euler-Maruyama scheme applied to small noise problems. The adaptive technique is p-mean convergent and computes simultaneously all the trajectories, using the same time-step on all trajectories. Our adaptive algorithm is tested on several examples arising in applications and shown to perform much better than the fixed step-size schemes.
A Content Analysis of Child Care Advocacy Messages Communicated by the Child Care Advocacy Association of Canada from 2005-2010
Authors: Summers Bernadette
Published: June 2021

This research project used a content analysis to examine advocacy messages in documents released by a social movement organization, the Child Care Advocacy Association of Canada, from2005-2010. Of particular interest were advocacy messages that focused on national childcare system issues (accessibility, affordability, quality, universality, publicly funded, delivery, governance, ECEC staffing issues and market approach)and policy frames (child development, equity for disadvantaged groups, poverty reduction, labour force participation, business case-human capital and rights of children, women and families) used to justify the need for system changes. Findings indicate that CCAAC's advocacy messages remained consistent from 2005-2010 with slight increases in 2005, 2008, and 2009 when the political climate at the federal level offered opportunities for CCAAC to play up certain messages to their audiences.
Plane wave ultrasound imaging using synthetic aperture image reconstruction techniques
Authors: Yang Dae-Myoung (Danny)
Published: June 2021

Ultrasound imaging based on transmitting plane waves (PW) enables ultrafast imaging. Coherent PW compounding ultrasound imaging can reach the image quality of optimal multifocus image. In the image reconstruction, it was assumed that an infinite extent PWs was emitted. In this thesis, we propose a new image reconstruction algorithm – Synthetic-aperture plane-wave (SAPW) imaging – without using this assumption. The SAPW imaging was compared with the PWs imaging in numerical simulations and experimental measurements. The measured RF data in PW imaging was first decoded in the frequency domain using a pseudoinverse algorithm to estimate the RF data Then, SAPW RF data were used to reconstruct images through the standard synthetic transit aperture (STA) method. Main improvements in the image quality of the SAPW imaging in comparison with the PWs imaging are increases in the depth of penetration and the field of view when contrast-to-noise ratio (CNR) was used as a quantitative metric.
Pendekatan Regresi Logistik Pada Perataan Laba
Authors: Octisari Sully Kemala , Wijaya Minadi , Baroroh Aisyah Ayu
Published: June 2021

Earnings management is one of the management actions for engineering company performance. The act of engineering profit can be said to be legal by some parties. There are many ways to do earnings management, one of which is income smoothing. This researcher aims to analyze the profitability of income smoothing in the metal industry and the like in 2011-2018. In this study using logistic regression using a dummy. The results of this study indicate that profitability and firm size do not have a significant effect on income smoothing, while financial leverage has a significant effect on income smoothing. The implication of this research is that 1) the company's efforts to attract investors do not have to focus only on profitability and company size 2) the company must pay attention to the ratio between the company's liabilities and the company's assets.
Neural Network Facial Authentication for Public Electric Vehicle Charging Station
Authors: Abdul Haris Muhamad Amin Husni , Lim Sin Liang
Published: June 2021

This study is to investigate and compare the facial recognition accuracy performance of Dlib ResNet against a K-Nearest Neighbour (KNN) classifier. Particularly when used against a dataset from an Asian ethnicity as Dlib ResNet was reported to have an accuracy deficiency when it comes to Asian faces. The comparisons are both implemented on the facial vectors extracted using the Histogram of Oriented Gradients (HOG) method and use the same dataset for a fair comparison. Authentication of a user by facial recognition in an electric vehicle (EV) charging station demonstrates a practical use case for such an authentication system.
PROTECTION OF SELF-DEVELOPMENT RIGHT FOR CONVICTED CRIMINALS IN THE ENVIRONMENT OF CLASS IIA CORRECTIONAL INSTITUTIONS OF BENGKULU
Authors: Wins Henny , Adyan Antory Royan , Hatrik Hamzah
Published: June 2021

The correctional institutions developing nowadays adopts a penal system that is more educating and fostering. Formerly, correctional institutions adhered to a prison system that was more of a punishment for crimes committed by the criminals. In general, fostering the prisoners aims to make prisoners to be fully human through the strengthening of faith (mental endurance) as well as to foster the prisoners to be able to integrate naturally in prison and in a wider life (community) after serving their convictions. This study on the protection of self-development right for convicted criminals in the environment of class IIA correctional institutions of Bengkulu was an empirical legal research that aimed to find out and to analyze the implementation of protection of self-development right for prisoners as well as to find out and to analyze the obstacles faced in implementing the protection of self-development right for prisoners in the environment of class IIA correctional institutions of Bengkulu. Data sources of this research were primary and secondary data. Data collection methods applied in this study were interviews and documentation. The data processing method used was descriptive qualitative. From the results of the study, it was revealed that: 1) the implementation of the fulfillment of juvenile prisoners’ right to obtain education at the class IIA correctional institutions of Bengkulu had not been fully fulfilled. To fulfill the educational process, there are Program Kejar (Kelompok Belajar/Study Group) of Package A (equivalent to elementary school), Package B (equivalent to junior high school), and Package C (equivalent to high school) as a series of processes for fulfilling the right for education for juvenile prisoners. But the program had not run optimally according to standards set by the government. Most of the juvenile prisoners make self-taught learning; 2) in the implementation of the education process in prisons, there were several factors that become obstacles in its implementation. These factors included the lack of partners to carry out the process of fulfilling the right for education, the facilities available in correctional institutions were inadequate, the limited teaching staffs provided by the local Education Department, lack of supervision on juvenile prisoners if they were pursuing education outside correctional institutions, as well as minimal budget allocations for educational purpose in correctional institutions.
JURIDICAL REVIEW OF THE FACILITATION OF COMMUNITY PLANTATION DEVELOPMENT BY PLANTATION COMPANIES
Authors: Marwassari Lestariana , Yamani M. , Kontesa Emelia
Published: June 2021

The government regulates the facilitation of community plantation development as much as 20% of the area of rights by plantation companies. This provision which is the obligation of the company was still not regulated in a clear and firm legal arrangement so that it created multiple interpretations in its application. Based on this matter, the writer was motivated to analyze the legal arrangements for the facilitation of community plantation development by plantation companies and the obstacles encountered in the implementation. The plantation company which was the focus of the research was PT. Pamor Ganda with Business Right (known as HGU in Indonesia abbreviation) Number 16/1989 by studying the HGU extension document. This was a normative research with a statutory approach. The method of analysis performed was content analysis, then the interpretation was carried out to understand the conclusions. The results showed that legal arrangements in the land sector, Micro, Small, Medium Enterprises (MSMEs), and plantations had not been able to solve the problems that exist in the implementation of facilitation of community plantation development by plantation companies. The company's obstacle was that the plasma farmers' plantation area around the companies’ plantation area had not been able to meet the 20% area requirement. While PT. Pamor Ganda had fulfilled its obligation to facilitate community plantation development by releasing its 114 hectare of HGU area.
KECEPATAN EFEKTIF MEMBACA TEKS NONFIKSI SISWA KELAS VIII SMP NEGERI 3 KOTA BENGKULU
Authors: Khairunnisa Hafiza , Ariesta Ria , Purwadi Agus Joko
Published: June 2021

Tujuan dari penelitian ini mendeskripsikan kecepatan efektif membaca teks nonfiksi siswa kelas VIII SMP Negeri 3 Kota Bengkulu. Jenis penelitian adalah kuantitatif dengan menggunakan metode deskriptif. Sampel penelitian berjumlah 32 orang yaitu siswa kelas VIII SMP Negeri 3 Kota Bengkulu. Penentuan sampel pada penelitian ini menggunakan purposive sampling, dan instrumen penelitian yang digunakan adalah instrument tes. Validitas dan reabilitas diakukan dengan cara validitas isi. Teknik pengumpulan data yang digunakan adalah teknik analisis statistik deskriptif. Berdasarkan deskripsi penelitian dapat disimpulkan bahwa hasil tes kecepatan efektif membaca teks nonfiksi siswa kelas VIII SMP Negeri 3 Kota Bengkulu termasuk ke dalam kategori sedang, dan rata-rata hasil tes kecepatan efektif membaca teks nonfiksi siswa kelas VIII SMP Negeri 3 Kota Bengkulu menunjukkan hasil kecepatan efektif membaca dengan skor tertinggi yang dicapai oleh responden dengan persentase pemahaman 79% dan rata-rata waktu yang digunakan adalah 1.89 menit. Data tersebut merupakan hasil tes responden siswa sebanyak 32 orang.
THE PORTRAYAL OF FEMALE CHARACTER IN “LADY ELEANORE’S MANTLE” BY NATHANIEL HAWTHORNE
Authors: Ramadhani Putri
Published: June 2021

This research concern with the analysis of female character in Lady Eleanore’s Mantle by Nathaniel Hawthorne. The purpose of the research is to describe the female character of Lady Eleanore’s Mantle by Nathaniel Hawthorne short stories by analyzing the main female characters to the development of the plot. This research using two methods, which are qualitative and descriptive. The problem of research is want to desribe the portrayal of female character in Lady Eleanore’s Mantle. The woman is a beautiful, rich, and has high position in her community. Always get more attention and special treatment from other people and make her became to an arrogant girl. At the end, the woman get punishment and died tragically
ILMIZI model in environmental learning during COVID-19: Improving students’ attitudes in University
Authors: Ichsan Ilmi Zajuli , Purwanto Agung , Rahmayanti Henita , Koc Isil , Turan Merve , Gomes Paulo Weslem , Rahman Md. Mehadi , Auliandari Lia , Adlini Miza Nina , Permana Irvan , Adri Helmia Tasti
Published: June 2021

Environmental education amid Coronavirus Disease 2019 (COVID-19) pandemic requires innovation. The pandemic situation need to improving student attitudes in maintaining the environment need an improvement by conducting various innovations and one of them is ILMIZI learning model utilization. The research aim was to improve student attitudes with the ILMIZI model. The research method is experimental without a control class. Samples involved in the research consist of 61 students with a treatment of environmental learning using the ILMIZI model. The Instrument used in this research was the attitude instrument with a scale of 1-5. The research results suggest that t-value (.231) > t-statistic (1.67) indicating that the ILMIZI model is not yet effective in improving the students’ attitudes in maintaining the environment. The pretest score (83.80) and post-test score (83.62) are not significantly different. The conclusion drawn from the research is that the ILMIZI model has not effective in improving student attitudes in maintaining the environment during COVID-19.
Botanical application: Android-based learning media to enhance interest in learning plant material
Authors: Aldya Riantina Fitra , Arifendi Rio Febrianto
Published: June 2021

Balikpapan Botanical Garden School has a very supportive learning environment, especially in studying plant material, but there are still many students who show low interest in learning so that an application in the form of android application to foster student interest in learning related to plants. This research aims to determine the feasibility of the botanical application as the further development of a flash application with the same theme to enhance interest in learning plant material. This research is used Research and Development (R&D) with ADDIE model which includes the analysis, design, development, implementation, and evaluation stage. The data were collected using a questionnaire to measure students’ learning referring to Mitchell's theory with 25 questions. The result showed that the botanical application is feasible to use with a score of 3,86 (feasible) and 4,16 (very feasible) according to media and material experts, and also a score of 4,47 (very feasible) according to the students. It also can enhance interest in learning plant material at the significance level of 0.002<0.05 with 46,6% of students reach the high criterion and the other 53,3% reach the moderate criterion of interest. This android-based of botanical application turns out to be able to enhance interest in learning about plant material due to learners' option to choose learning content depending on their interest.
PERSONALIZED MEDICINE: REDEFINING CANCER TREATMENT USING MACHINE LEARNING
Authors: Kumar Akash , Santhosh Kandibanda Sai
Published: June 2021

We are proposing a novel model for
Classify the given genetic variations/mutations based
on evidence from text-based clinical literature. Our
model helps Molecular pathologists to classify the
cancer tumor variations into 9 classes. As before
molecular pathologists have to manually study all the
variations which took a lot of time and effort. To
solve this problem we are making a machine learning
model and training it on more than 4k data points
which is provided by the cancer organization of
America for research and development purposes and
achieve 97% accuracy by applying the optimal
machine learning algorithm.
A REVIEW ON RENEWABLE ENERGY INTEGRATION FOR ELECTRIC VEHICLES
Authors: Parmar Shubham , Patel Mihir
Published: June 2021

Electric vehicles (EVs) or renewable energy
(RE) sources provide the potential to significantly reduce
emissions of carbon as of the economy's transport & power
generation sectors. There can be a range of impacts and
benefits to the mass adoption of EVs, with the ability to aid
in integrating renewable energy into current electricity
grids. Present literature on EVs, power grid as well as the
integration of RE is reviewed in this paper. Literature’s
main methods and assumptions are deliberated. Economic,
environmental & the grid effects of EVs are studied.
Several research studies have been conducted on the
ability of EVs to integrate Res. literature indicates that
excess RE generated on a power grid can be reduced
significantly. In the Vehicle to grid (V2G) idea the Plug-in
electric vehicle (PEVs) can be performed as the load or as
the distribution energy source. By using the V2G idea the
performance of the electricity grid will increases. The
efficiency, stability & reliability will increase.
Comparative Analysis of Constructive, Clinical and Biomechanical Features of Screw, Bone and Combined Dental Implant Chuiko-Alymbaev
Authors: Erkimbekov I. , Zholdoshev Ch. , Kulnazarov A. , Abdymomunov A.
Published: June 2021

Abstract. This work is devoted to a comparative analysis in the context of the structural, clinical and biomechanical features of three types of dental implants: screw, bone and combined (Chuiko-Alymbaeva). A description of the strengths and weaknesses of each type of implant.
‘Terres vaines et vagues’: Ecocriticism and Breton Wastelands in Visual and Literary Representation
Authors: Coughlin Maura
Published: June 2021

Despite their long histories as a culturally valuable commons and sites of biodiversity, the Breton landes were frequently depicted by nineteenth-century authors, travellers and administrators as wild, unproductive wastelands. While the architects of France's ‘interior colonization’ identified such areas as an ugly, infertile expanse to be cleared and put to use, many visual artists were producing a compelling counter-narrative, representing the landes and zones humides as places of beauty and reverie. This article examines the work of artists such as François Blin, Camille Bernier, Alexandre Ségé and Henri Rivière from an ecocritical perspective, arguing that their work contributed to a discourse of preservation by encouraging new ways of seeing the land, not for its extractive utility but as a space of unexpected splendour and enchantment. Far from a regressive form of nostalgia, these images encourage a unique ‘dwelling perspective’ which uses aesthetic beauty to reveal the area's ecological potential and to articulate a call for responsible environmental stewardship.
Évolution du phénomène de traduction dans le domaine littéraire de langue bretonne
Authors: Blanchard Nelly
Published: June 2021

Arguing that the concept of littérature-monde conceals unequal relations between literary cultures, this article examines the socio-economic contexts of literary translation from and into Breton from the fifteenth to the twenty-first century. The value of translation across the corpus of 1025 texts lies primarily in creating intercultural relationships and promoting cultural diversity. Translation into Breton represents a vital defence of a language with dwindling speaker numbers: in the late 1970s it increases dramatically, with littérature de jeunesse spearheading a change in state policy allowing regional languages to be taught in schools. Yet translation can also reinforce an existing power imbalance, highlighting the central role played by French in the linguistic and literary construction of Breton society. Poetry, songs and contes translated from Breton often perpetuate stereotypes of a bardic, oral culture, while nationalist writers reject self-translation into French as capitulation before the dominant culture. Since the 1980s, many have chosen to bypass French by translating into languages such as Welsh, Scottish, Irish or Catalan, creating a network of minority literatures. Since the market for Breton translation is so small, however, such texts serve as valuable identity markers, a symbolic, affective force articulating a quest for socio-political legitimacy via literature.
Performing Identities, Displacing Homelands: Transnational Poetics in the Theatre of Paol Keineg
Authors: de Saussure Annie
Published: June 2021

While Breton literature has often been viewed as either nationalist or nostalgic, Paol Keineg offers alternative expressions of Breton consciousness. From his first published work, Le Poème du pays qui a faim (1967), inspired by Aimé Césaire, Keineg inscribes Breton literature in transnational paradigms while resisting essentialist and nationalist discourses through literary strategies of displacement. This article compares two protagonists in Keineg's theatre. First, I describe the decolonial context of Keineg's first play Le Printemps des bonnets rouges (1972), written with Jean-Marie Serreau and modelled on Césaire's theatre of négritude, before analysing the poetic displacements of the play's Breton hero Sebastian Ar Balp. I then explore how Keineg's depiction of Irish nationalist Sir Roger Casement in Terre lointaine (2004) highlights his contradictions and ambiguities, and deploys ghosts, or spectres in the Derridean sense, which allow for multiple histories, geographies, and identities to overlap, further inscribing them in transnational paradigms.
Empirical and long-term therapy for endometriosis-associated pelvic pain
Authors: Kuznetsova I. V.
Published: June 2021

Endometriosis is a common disease, the diagnosis and treatment of which is still a matter of debate. One of the main symptoms of endometriosis -pelvic pain is a particular problem due to the difficulties in identifying the cause and the lack of sufficient effect from surgical and medical treatment. The literature review presents current data on the prevalence, clinical characteristics and methods of individualized therapy in patients with pelvic pain established or presumably associated with endometriosis.
LEGAL REGULATION ON THE CREATION AND FUNCTIONING OF INNOVATION CLUSTERS IN UKRAINE
Authors: Христина Іваницька
Published: June 2021

The article reviews the regulatory framework on the basis of which the creation and functioning of innovation clusters as an association of objects of innovative infrastructure of Ukraine.During the research, the author concludes that it is advisable to classify the regulatory regulation of the activity of innovation clusters in Ukraine into two categories: general and special. The general regulatory framework is aimed at creating elements of innovation clusters as legal entities; special aimed at regulating issues of innovation and intellectual property.At the same time, the basic principles of creation and functioning of the legal framework governing the issues of innovation clusters are highlighted: systematicity, accessibility and legality.In the article it is stated that legislative regulation, covering the issues of the functioning of the innovation clusters is incomplete and fragmented, which in turn impedes the full, strategic and cost-effective development of innovation clusters. Hence, the author advices to propose the legislator to regulate the investigated issue at the level of a separate legal act.Besides proper legislative framework, the author pays attention to the necessity of the attraction of budgetary and extra-budgetary funding, including facilitating the participation of clusters in competitions and events conducted by state and regional development institutes, state authorities and local self-government bodies. It is also obvious that there is a need of facilitating the promotion and sale of innovative products of cluster participants in the domestic and world markets; implementation of projects of cluster participants with involvement of state and regional development institutes.At the end of the research the author generates the basic directions of improvement of the policy of legal regulation of the cluster innovation system of Ukraine, proposes concrete measures in the direction of its improvement and modernization.
The concept infringement of subjective copyright: a theoretical aspect
Authors: Shtefan Olena
Published: June 2021

Shtefan O. The concept infringement of subjective copyright: a theoreticalaspect. The article examines the problem of protection of subjective copyright at the doctrinal level. The source base analyzed in the article revealed the lack of a unified approach to the definition of copyright infringement, the criteria for classifying infringements and their characteristics. The author 's approach to the solution of the outlined problem is offered in the article.In particular, the proposed following definition of copyright infringement is a culpable, unlawful, punishable act (action or omission) that harms or infringes on the personal non-property and / or property rights of the copyright holders for which the legal liability arises. The basis of protection of rights is called by civil law “non-recognition of rights". Summarizing the existing definitions of this term in the doctrine, the author proposes to understand the non-recognition of rights as a passive denial of a person's copyright to a work, which does not directly harm the subjective right of the copyright subject, but creates uncertainty in the legal status of the holder. including in its relations with third parties regarding the use of the object of copyright.In the article, the author, based on the analysis of case law, examines the misuse of the work, as any use of copyright both within the contract and outside the contract, which violates the property rights and personal non-property rights of copyright subjects. The most common are non-contractual copyright infringements related to the illegal use of works. Such violations include, in particular: posting works on the Internet sites forfree (paid or free) access without the permission of the relevant subject, presentation of works in cafes, bars, restaurants for a fee or without them (without royalty payment), work or part of it in the memory of a mobile phone for a fee or without such, etc. The article concludes that, as a rule, intangible copyrights are infringed at the same time as property rights, is a derivative of infringement of property copyrights related to the useof the work. Therefore, copyright infringement is complex. The article concludes that copyright infringement is complex.Key words: copyright, infringement, classification of infringements, signs of infringement, infringement of subjective copyright.
Voice parade parameters: Investigating the effect of parade size and voice sample duration on earwitness identification accuracy.
Authors: Paver Alice , Smith Harriet M. J. , Pautz Nikolas , McDougall Kirsty , Mueller-Johnson Katrin , Nolan Francis
Published: June 2021

A voice parade enables collection of earwitness identification evidence, but the current procedure is costly and time-consuming. Hence, this study investigates whether the number of foils or duration of samples could safely be reduced. Listeners attempted to recognize a voice amongst same-accented foils in target-absent or target-present parades (constructed as per Home Office guidelines, 2003). Six male English speakers were chosen as targets; three SSBE, and one each from York, Bradford and Wakefield. Listeners were exposed to one target for 60s, before hearing a parade of nine voices (Experiment 1) or six voices (Experiment 2) in either 15s, 30s or 60s samples. Overall performance was low, but higher in target-present versus target-absent. Performance also varied by target-speaker. Results suggest samples can safely be reduced from 60s to between 15s and 30s, but parade size should remain at nine-person.
Effects of Climate Change on Weeds and Invasive Alien Plants in Sri Lankan Agro-Ecosystems: Policy and Management Implications
Authors: Marambe Buddhi , Wijesundara Siril
Published: June 2021

Changes in the climate have worsen the problems caused by weeds and invasive alien plants (IAPs) in agro-ecosystems at global scale resulting from their changes in the range and population densities. Over the past six decades, Sri Lanka has experienced a slow but steady increase in annual environmental temperature by 0.01–0.03°C. Increasing extreme events of rainfall, wetter wet seasons, and drier dry seasons are some of the characteristic features of the changes in the climate observed in Sri Lanka over the years. The Ministry of Environment (MOE) in Sri Lanka has established a National Invasive Species Specialist Group (NISSG) in 2012 and adopted the National Policy on Invasive Alien Species (IAS) in Sri Lanka, Strategies and Action Plan in 2016. Further, the MOE has developed and adopted protocols to assess the risk of IAS at pre- and post-entry level to the country while incorporating climate change concerns. Periodic risk assessments have being carried out to prioritize actions against IAS in Sri Lanka. The Ministry of Agriculture as adopted a National Weed Strategy (NWS) and has identified the Weeds of National Significance (WONS) under different priority crops. A study done in 2014 has clearly shown that weed control costs in agricultural lands in several district of Sri Lanka were nearly doubled during the years that experiencedEl NiñoSouthern Oscillation (ENSO). Further, studies have clearly indicated that IAPs also survive, expand and impact the continuously disturbed environments in agro-ecosystems.Panicum trichocladum, a species listed as a potential invasive based on the risk assessment done in 2016, has shown an increase in its population density and distribution in Sri Lanka during the last 2–3 years. However, weeds and IAPs in agro-ecosystems have drawn less attention of policy makers, scientists, and practitioners in relation to impact of climate change in island ecosystems. This paper focuses on the scientific evidence reported in agro-ecosystems in Sri Lanka on climate-related impacts on agriculturally important weeds and IAPs, and the efforts made to manage their introduction and spread across the country.
Suitability of Legacy Subsurface Data for Nascent Geoenergy Activities Onshore United Kingdom
Authors: Ireland Mark T. , Brown Rachel , Wilson Miles P. , Stretesky Paul B. , Kingdon Andrew , Davies Richard J.
Published: June 2021

The decarbonization of energy systems to achieve net zero carbon emissions will likely see the rapid development of carbon capture and storage, energy storage in the subsurface and geothermal energy projects. Subsurface data, in particular seismic reflection surveys and borehole data are vital for geoscientists and engineers to carry out comprehensive assessments of both the opportunities and risks for these developments. Their cost of acquisition means that such legacy data are commonly the only mechanism for site selection so biased data distribution must be accommodated. Here, legacy subsurface data from United Kingdom onshore hydrocarbon and coal exploration in the United Kingdom are collated and reviewed for their suitability for geoenergy activities. We provide a description of the spatial coverage and a chronology of the acquisition of key seismic reflection and borehole data, as well as examine data resolution and limitations. We discuss the implications of spatial variability in subsurface datasets and the associated subsurface uncertainty as this is vitally important to understanding the suitability of data for decision making. We examine societal aspects of data uncertainty and discuss that when the same data are used to communicate subsurface uncertainty and risk, the source of the data should also be considered, especially where data are not easily publicly accessible. Understanding the provenance and quality criteria of data are vitally important for future geoenergy activities and public confidence in subsurface activities. Finally, we ask should there be minimum data collection criterion, such as resolution requirements, ahead of subsurface activities with potentially significant impacts to the environment, economy, and society?
Evolution of Seismicity During a Stalled Episode of Reawakening at Cayambe Volcano, Ecuador
Authors: Butcher S. , Bell A. F. , Hernandez S. , Ruiz M.
Published: June 2021

Cayambe Volcano is an ice-capped, 5,790 m high, andesitic-dacitic volcanic complex, located on the equator in the Eastern Cordillera of the Ecuadorian Andes. An eruption at Cayambe would pose considerable hazards to surrounding communities and a nationally significant agricultural industry. Although the only historically documented eruption was in 1785, it remains persistently restless and long-period (LP) seismicity has been consistently observed at the volcano for over 10 years. However, the sparse monitoring network, and complex interactions between the magmatic, hydrothermal, glacial, and tectonic systems, make unrest at Cayambe challenging to interpret. In June 2016 a seismic “crisis” began at Cayambe, as rates of high frequency volcano-tectonic (VT) earthquakes increased to hundreds of events per day, leading to speculation about the possibility of a forthcoming eruption. The crisis began 2 months after the Mw7.8 Pedernales earthquake, which occurred on the coast, 200 km from Cayambe. Here we show that the 2016 seismicity at Cayambe resulted from four distinct source processes. Cross correlation, template matching, and spectral analysis isolate two source regions for VT earthquakes–tectonic events from a regional fault system and more varied VTs from beneath the volcanic cone. The temporal evolution of the LP seismicity, and mean Q value of 9.9, indicate that these events are most likely generated by flow of hydrothermal fluids. These observations are consistent with a model where a new pulse of magma ascent initially stresses regional tectonic faults, and subsequently drives elevated VT seismicity in the edifice. We draw comparisons from models of volcano-tectonic interactions, and speculate that static stress changes from the Pedernales earthquake put Cayambe volcano in an area of dilation, providing a mechanism for magma ascent. Our findings provide a better understanding of “background” seismicity at Cayambe allowing faster characterization of future crises, and a benchmark to measure changes driven by rapid glacial retreat.
Evaluation of Fish Communities in Daya Bay Using Biomass Size Spectrum and ABC Curve
Authors: Xu Shannan , Guo Jianzhong , Liu Yong , Fan Jiangtao , Xiao Yayuan , Xu Youwei , Li Chunhou , Barati Bahram
Published: June 2021

Based on the data collected by four trawl surveys during 2016–2017, we applied biomass size spectrum (BSS) and abundance–biomass comparison (ABC) curve to assess the status of fish communities’ status in Daya Bay, China. Our findings indicated a unimodal pattern and biomass size ranged from −2 to 10 grain levels and the pattern of the Sheldon-type BSS of fish in Daya Bay. Moreover, fishes in the range of four to eight size class were relatively abundant. The highest peak belonged to the two to four grain level (log2 size bins), mainly consisting of Leiognathus brevirostris, Callionymus meridionalis, Callionymus koreanus, Evynnis cardinalis, Trachurus japonicus, and other small fishes. The curves of the BSS in spring and winter were relatively flat and comprised a large curvature. The summer and autumn curves were comparatively steep, and the seasonal curvature was small. The curvatures of the curve were mainly related to a large number of small Evynnis cardinalis and a small number of large-sized Harpadon nehereus and Leiognathus ruconius. In our study, it was observed that the number and the size of the breeding population, trophic levels, migration habits, and other life history characteristics, as well as anthropogenic disturbances (especially overfishing), significantly affected the peak shape, slope, or curvature of the fish BSS, with overfishing being the main factor. The ABC curve exhibited that Daya Bay was in a critical state of disturbance throughout the year. The spring, summer, and autumn were in severe disturbance, while the winter was in moderate disturbance.
IgE Epitopes of the House Dust Mite Allergen Der p 7 Are Mainly Discontinuous and Conformational
Authors: Curin Mirela , Huang Huey-Jy , Garmatiuk Tetiana , Gutfreund Sandra , Resch-Marat Yvonne , Chen Kuan-Wei , Fauland Kerstin , Keller Walter , Zieglmayer Petra , Zieglmayer René , Lemell Patrick , Horak Friedrich , Hemmer Wolfgang , Focke-Tejkl Margarete , Flicker Sabine , Vrtala Susanne , Valenta Rudolf
Published: June 2021

Background

Several studies indicate that Der p 7 is an important and clinically relevant allergen of Dermatophagoides pteronyssinus which should be included in vaccines for treatment of house dust mite (HDM) allergy. Aim of this study was to characterize the IgE epitopes of Der p 7.

Methods

Recombinant Der p 7 was expressed and purified, analyzed for fold by circular dichroism and tested for its allergenic activity by basophil activation. Seven overlapping, surface-exposed peptides (P1–P7) with a length of 27 to 37 amino acids, which spanned the Der p 7 sequence, were synthesized and tested for IgE reactivity and allergenic activity by basophil activation assay. Carrier-bound peptides were studied for their ability to induce allergen-specific IgG antibodies in rabbits. Peptide-specific antibodies were used to inhibit allergic patients` IgE binding to Der p 7 by ELISA for mapping of IgE epitopes.

Results

rDer p 7 showed high allergenic activity comparable with Der p 5, Der p 21, and Der p 23. None of the seven tested peptides showed any IgE reactivity or allergenic activity when tested with HDM- allergic patients indicating lack of sequential IgE epitopes on Der p 7. IgE inhibition experiments using anti-peptide specific IgGs and molecular modeling enabled us to identify discontinuous, conformational IgE epitopes of Der p 7.

Conclusion and Clinical Relevance

IgE epitopes of Der p 7 belong to the conformational and discontinuous type whereas sequential Der p 7 peptides lack IgE reactivity. It should thus be possible to construct hypoallergenic vaccines for Der p 7 based on carrier-bound allergen peptides.