bluuebunny/crossref_metadata_2025 huggingface dataset:
Phenotypic Changes in T and NK Cells Induced by Sputnik V Vaccination
Authors: Boyko Anna A. , Ustiuzhanina Maria O. , Vavilova Julia D. , Streltsova Maria A. , Kust Sofya A. , Siniavin Andrei E. , Astrakhantseva Irina V. , Drutskaya Marina S. , Kovalenko Elena I.
Published: June 2023

A highly effective humoral immune response induced by the Sputnik V vaccine was demonstrated in independent studies, as well as in large-scale post-vaccination follow-up studies. However, the shifts in the cell-mediated immunity induced by Sputnik V vaccination are still under investigation. This study was aimed at estimating the impact of Sputnik V on activating and inhibitory receptors, activation and proliferative senescence markers in NK and T lymphocytes. The effects of Sputnik V were evaluated by the comparison of PBMC samples prior to vaccination, and then three days and three weeks following the second (boost) dose. The prime-boost format of Sputnik V vaccination induced a contraction in the T cell fraction of senescent CD57+ cells and a decrease in HLA-DR-expressing T cells. The proportion of NKG2A+ T cells was down-regulated after vaccination, whereas the PD-1 level was not affected significantly. A temporal increase in activation levels of NK cells and NKT-like cells was recorded, dependent on whether the individuals had COVID-19 prior to vaccination. A short-term elevation of the activating NKG2D and CD16 was observed in NK cells. Overall, the findings of the study are in favor of the Sputnik V vaccine not provoking a dramatic phenotypic rearrangement in T and NK cells, although it induces their slight temporal non-specific activation.
Symptom-Specific Hospital Contacts in 12–18-Year-Olds Vaccinated against COVID-19: A Danish Register-Based Cohort Study
Authors: Berg Selina Kikkenborg , Wallach-Kildemoes Helle , Rasmussen Line Ryberg , Nygaard Ulrikka , Birk Nina Marie , Bundgaard Henning , Ersbøll Annette Kjær , Thygesen Lau Caspar , Nielsen Susanne Dam , Christensen Anne Vinggaard
Published: June 2023

In this register-based real-life cohort study, changes in symptom-specific hospital contacts among 12–18-year-olds following two doses of the BNT162b2 COVID-19 vaccine compared to unvaccinated peers were investigated. Using national register data, vaccinated and unvaccinated adolescents were sex and age-matched each week during the inclusion period from May to September 2021. Symptom-specific hospital contacts covering ICD-10 R diagnoses were assessed before first the vaccine dose and after the second vaccine dose. Taking previous rates of symptom-specific hospital contacts into account, differences between vaccinated and unvaccinated adolescents were found. For some hospital contacts, higher rates were seen among the vaccinated, and for others, higher rates were seen among the unvaccinated. Unspecific cognition symptoms may be important to monitor in vaccinated girls, and likewise for throat and chest pain in vaccinated boys within the first months post-vaccination. In perspective, symptom-specific hospital contacts after vaccination against COVID-19 must be assessed by taking the risk of infection and symptoms following COVID-19 infection into account.
Mammary Glands of Women, Female Dogs and Female Rats: Similarities and Differences to Be Considered in Breast Cancer Research
Authors: Ferreira Tiago , Gama Adelina , Seixas Fernanda , Faustino-Rocha Ana I. , Lopes Carlos , Gaspar Vítor M. , Mano João F. , Medeiros Rui , Oliveira Paula A.
Published: May 2023

Breast cancer is one of the most common and well-known types of cancer among women worldwide and is the most frequent neoplasm in intact female dogs. Female dogs are considered attractive models or studying spontaneous breast cancer, whereas female rats are currently the most widely used animal models for breast cancer research in the laboratory context. Both female dogs and female rats have contributed to the advancement of scientific knowledge in this field, and, in a “One Health” approach, they have allowed broad understanding of specific biopathological pathways, influence of environmental factors and screening/discovery of candidate therapies. This review aims to clearly showcase the similarities and differences among woman, female dog and female rat concerning to anatomical, physiological and histological features of the mammary gland and breast/mammary cancer epidemiology, in order to better portray breast tumorigenesis, and to ensure appropriate conclusions and extrapolation of results among species. We also discuss the major aspects that stand out in these species. The mammary glands of female dogs and women share structural similarities, especially with respect to the lactiferous ducts and lymphatic drainage. In contrast, female rats have only one lactiferous duct per nipple. A comprehensive comparison between humans and dogs is given a special focus, as these species share several aspects in terms of breast/mammary cancer epidemiology, such as age of onset, hormonal etiology, risk factors, and the clinical course of the disease. Holistically, it is clear that each species has advantages and limitations that researchers must consider during the development of experimental designs and data analysis.
Rottlerin-Liposome Inhibits the Endocytosis of Feline Coronavirus Infection
Authors: Choi Jong-Chul , Jung Sung-Won , Choi In-Yeong , Kang Yeong-Lim , Lee Dong-Hun , Lee Sang-Won , Park Seung-Yong , Song Chang-Seon , Choi In-Soo , Lee Joong-Bok , Oh Changin
Published: May 2023

Rottlerin (R) is a natural extract from Mallotus philippensis with antiviral properties. Feline infectious peritonitis (FIP) is a fatal disease caused by feline coronavirus (FCoV) that is characterized by systemic granulomatous inflammation and high mortality. We investigated the antiviral effect of liposome-loaded R, i.e., rottlerin-liposome (RL), against FCoV. We demonstrated that RL inhibited FCoV replication in a dose-dependent manner, not only in the early endocytosis stage but also in the late stage of replication. RL resolved the low solubility issue of rottlerin and improved its inhibition efficacy at the cellular level. Based on these findings, we suggest that RL is worth further investigation as a potential treatment for FCoV.
Evaluation of a Porcine Endogenous Reference Gene (Internal Sample Control) in a Porcine Reproductive and Respiratory Syndrome Virus RT-qPCR
Authors: Munguía-Ramírez Berenice , Armenta-Leyva Betsy , Henao-Díaz Alexandra , Ye Fangshu , Baum David H. , Giménez-Lirola Luis G. , Zimmerman Jeffrey J.
Published: May 2023

Endogenous reference genes are used in gene-expression studies to “normalize” the results and, increasingly, as internal sample controls (ISC) in diagnostic quantitative polymerase chain reaction (qPCR). Three studies were conducted to evaluate the performance of a porcine-specific ISC in a commercial porcine reproductive and respiratory syndrome virus (PRRSV) reverse transcription-qPCR. Study 1 evaluated the species specificity of the ISC by testing serum from seven non-porcine domestic species (n = 34). In Study 2, the constancy of ISC detection over time (≥42 days) was assessed in oral fluid (n = 130), serum (n = 215), and feces (n = 132) collected from individual pigs of known PRRSV status. In Study 3, serum (n = 150), oral fluid (n = 150), and fecal samples (n = 75 feces, 75 fecal swabs) from commercial herds were used to establish ISC reference limits. Study 1 showed that the ISC was porcine-specific, i.e., all samples from non-porcine species were ISC negative (n = 34). In Study 2, the ISC was detected in all oral fluid, serum, and fecal samples, but differed in concentration between specimens (p < 0.05; mixed-effects regression model). The results of Study 3 were used to establish ISC reference limits for the 5th, 2.5th and 1.25th percentiles. Overall, the ISC response was consistent to the point that failure in detection is sufficient justification for re-testing and/or re-sampling.
Stormwater Harvesting Potential for Local Reuse in an Urban Growth Area: A Case Study of Melton Growth Area in the West of Melbourne
Authors: Sharma Ashok K. , Sanciolo Peter , Behroozi Amir , Navaratna Dimuth , Muthukumaran Shobha
Published: June 2023

Integrated urban water management approaches (IUWM) are implemented to address challenges from increases in water demand as a result of population growth and the impact of climate change. IUWM aims to utilize all water resources (stormwater, wastewater, and rainwater) based on fit-for-purpose concepts. Here, a local water utility in Melbourne’s Melton growth area explored the availability of stormwater as an alternative water resource for water service planning for a proposed residential development in an existing greenfield area of 13,890 hectares for 160,000 new houses by 2040. A methodology was developed for assessing the stormwater quantity and quality under land use change and different climatic conditions considering the availability of stormwater from the proposed urban development. The modelling results indicated that the amount of annual stormwater generated in the region increased by nearly four times to 32 GL/year under the 2040 full urban land use with high climate change. The provision of constructed wetlands in proposed development blocks was found to be efficient at removing TSS, TP, and TN, and able to retain over 90% of TSS, 77% of TP, and 52% of TN in all scenarios. Harvested stormwater, if treated to potable standards, can meet nearly 40% of water requirements for residential area needs.
Impact of Snowmelt Conditions on the Isotopic Composition of the Surface Waters of the Upper Ob River during the Flood Period
Authors: Papina Tatyana , Eirikh Alla , Kotovshchikov Anton , Noskova Tatiana
Published: June 2023

For many of the Siberian rivers, and the Upper Ob in particular, 70–80% of the volume of the annual water runoff is formed during the spring flood. Thus, factors influencing the formation of water runoff during the spring flood are paramount. We explain changes in the isotopic composition of the Upper Ob surface waters by changing different components’ contribution to the runoff water discharge over the spring flood period. We suggest estimating the time of meltwater flow from the Upper Ob watershed to the outlet section using the difference between the date of the complete melting of the snow cover in the catchment area and the date of the maximum light isotope composition of water in the outlet section. We show that a sharp short-term weighting of the isotopic composition of water in the river at the end of the first phase of the flood may be associated with the influx of autumn soil moisture, displaced from the soils by snowmelt waters.
Using Age Tracers to Estimate Ecological Rates in a Phytoplankton Model
Authors: Gross Edward , Holleman Rusty , Kimmerer Wim , Munger Sophie , Burdick Scott , Durand John
Published: June 2023

The phytoplankton distribution in estuaries is influenced by multiple spatially variable growth and loss processes. As phytoplankton are transported by tidal and net flows, they are exposed to changing conditions of turbidity, depth, temperature, stratification, and grazing. Understanding the factors influencing the observed phytoplankton distribution patterns will allow better-informed restoration and water management efforts. We developed a Lagrangian approach driven by three-dimensional hydrodynamic model results and a simple representation of the production and losses of phytoplankton, allowing a highly efficient closed-form solution for phytoplankton biomass. Our analysis used continuous observations of chlorophyll concentration at four stations and a near-synoptic chlorophyll dataset collected underway from a boat in the channels of Suisun Marsh in the San Francisco Estuary. We divided the study region into four compartments defined by the water depth and location. For each observation location, hydrodynamic model simulations calculated the time that water parcels spent in each of these compartments and the mean depth encountered by water parcels in those compartments. Then, using that information and continuous monitoring data, we inferred compartment-specific grazing rates and two additional ecological parameters. The underway chlorophyll dataset was used for model validation. The model predicted patterns of observed spatial and tidal variability in chlorophyll in Suisun Marsh. The modeling indicated that the chlorophyll concentration at a point in space in time depends largely on the relative exposure to shallow areas, with positive net productivity and deep areas having negative net productivity.
Water Use Efficiency in Young Citrus Trees on Metalized UV Reflective Mulch Compared to Bare Ground
Authors: Ghoveisi Hossein , Kadyampakeni Davie Mayeso , Qureshi Jawwad , Diepenbrock Lauren
Published: June 2023

A precise estimation of plant water use is crucial for efficient irrigation management and understanding of plant–water interactions. Metalized-polyethylene mulch as a ground cover, combined with irrigation management, can improve water and fertilizer use, efficiency growth, and yield of young citrus trees, compared to bare ground. Thus, a study was undertaken to (i) compare daily water use, using the stem heat balance (SHB) method on ≤4-year-old citrus trees using three irrigation methods, and (ii) to determine soil moisture content, as well as total available soil water (TASW) in the irrigated zone. Three irrigation methods, regulated deficit irrigation (RDI), conventional drip irrigation (CD), and microsprinkler irrigation (MS), were applied on two sandy soils in central and southwest Florida with treatments further split between trees grown on 2.4 m mulched beds (M) and bare ground (NM) to form a factorial design. Measurements included sap flow, canopy size, leaf area index (LAI) and soil moisture. The result of this study shows greater values for the trunk cross-sectional area, canopy volume and LAI for both mulch treatments, in comparison to bare ground treatments. The sap flow data suggest that RDI resulted in higher water use than both CD and MS. The hourly sap flow was 120, 99 and 163% greater in M-RDI than M-CD, NM-CD and NM-MS, respectively. Mulched ground cover showed a higher soil moisture average at all soil layers (8-, 15- and 45-cm depth). For instance, the mulched ground cover showed higher soil moisture (37%) at a 15 cm depth at the Entisol site, followed by 30% at a 45 cm depth and 25.3% at depth 45 cm for the Spodosol site. The TASW values varied between 100 to 136% for both mulch and bare ground treatments. The irrigation systems used showed water contents close to field capacity, indicating that water was not limiting despite the different irrigation schedules. The high-water uptake is ascribed to frequent irrigation applications and pulses, and improved water distribution in the irrigated zone as a result of the mulch. These findings demonstrate the potential of metalized-polyethylene mulch and regulated drip irrigation to enhance water use efficiency.
Gasification of Waste Machine Oil by the Ultra-Superheated Mixture of Steam and Carbon Dioxide
Authors: Frolov Sergey M. , Silantiev Anton S. , Sadykov Ilias A. , Smetanyuk Viktor A. , Frolov Fedor S. , Hasiak Jaroslav K. , Vorob’ev Alexey B. , Inozemtsev Alexey V. , Inozemtsev Jaroslav O.
Published: June 2023

Reported in the article is further progress in the development of the novel pulsed detonation gun (PDG) technology for the conversion of organic wastes into syngas in a two-component gasifying agent (GA) containing ultra-superheated steam and carbon dioxide obtained by pulsed detonations of a natural gas–oxygen mixture at a frequency of 1 Hz. Experimental studies were carried out on a waste converter with a 40 dm3 flow reactor and two PDGs with a total volume of 2.4 or 3.2 dm3, which is approximately a factor of 6 and 4.5 less than in previous studies, respectively. The objective of the research was to find the design and operation parameters of the waste converter that provide a minimum amount of CO2 in the gasification products. Waste machine oil was used as a feedstock. It is shown that, compared with the earlier experiments with a higher average temperature of the reactor wall and with a PDG of a much larger volume, the contents of H2, CO, CH4, and CO2 in the syngas remained virtually unchanged, whereas the efficiency of the gasification process increased significantly: the use of 1 g of natural gas made it possible to gasify up to 4 g of the feedstock. It is also shown that the determining role in the gasification process of liquid feedstock is played by the feedstock residence time in the PDG rather than in the reactor. The minimum ratio between the flow rates of the GA and liquid feedstock, the minimum ratio between the flow rates of combustible gas and liquid feedstock, as well as the actual GA consumption in the gasification process are determined experimentally.
'Breaking the cycle': a qualitative study exploring general practitioners’ views of infant mental health
Authors: De Natale Anna , Hall Sophie , McFadyen Anne , Minnis Helen , Blane David N
Published: June 2023

Background

Infants living in areas of socioeconomic deprivation are more likely to have adverse childhood experiences (ACEs), which are associated with infant mental health (IMH) problems and poor physical and mental health outcomes throughout the life course. As part of the development of IMH services in Scotland, studies are being conducted to explore various stakeholders’ perspectives.

Aim

To understand the views and experiences of GPs working in socioeconomically deprived areas in relation to IMH.

Design & setting

Qualitative study with GPs working in deprived urban communities in Scotland, UK.

Method

Semi-structured interviews were conducted with 12 GPs from 11 practices. Transcribed interviews were thematically analysed, following the Braun and Clarke framework, using NVivo (version 12) software.

Results

The following three overarching themes are presented: (1) Deep End GPs’ inherent understanding of IMH, owing to their placement in deprived communities and their under-recognised role in current IMH provision; (2) Factors influencing how communities might perceive IMH, including the potential associations of IMH with parental blame or judgement in areas of socioeconomic deprivation; and (3) Using previous experience to visualise future IMH service delivery, particularly improving on current shortcomings of connectivity and accessibility of services, to develop successful new services.

Conclusion

GPs in areas of socioeconomic deprivation have a deep understanding of the issues affecting IMH, although do not necessarily relate to the term ‘IMH’. New community-based IMH services are much needed, particularly in deprived areas. However, the pre-existing role of primary care must be recognised, supported, and integrated into new services, alongside training to increase IMH awareness among GPs and other primary healthcare professionals (HCPs).
Étude de la qualité vocale dans le chant lyrique
Authors: Garnier Maëva , Sotiropoulos David , Poitevineau Jacques , Castellengo Michèle , Dubois Danièle , Henrich-Bernardoni Nathalie
Published: May 2023

This paper presents the main steps of a research project. It aims at understanding the notion of voice quality in western operatic singing, in studying what the singing teachers perceive while listening to a given voice, and how they orally express their perception. Trained singers and singing teachers were asked to speak about voice quality, while producing different voice qualities on a given musical sentence or while listening to singing examples. A linguistic analysis was conducted on their speech. It provided with part of the vocabulary related to the notion of voice quality, and helped to understand the underlying concepts. The possible correlates between acoustical parameters and verbal criterions were also explored.
Les stratégies normatives du traducteur à travers l’analyse contrastive d’un discours politique
Authors: Sánchez Cárdenas Beatriz
Published: May 2023

Les travaux de Toury (1980) montrent que toute traduction est une activité soumise à des normes. Sa théorie veut que les traducteurs se soucient moins des normes d 'adéquation que de celles de l' acceptabilité. Ainsi, les codes dominants de la culture d'arrivée sont décisifs dans le texte traduit. Ces deux concepts permettent d'analyser les traductions du discours d'investiture de Barack Obama (Washington 20/01/09) dans deux variantes de l'espagnol : le portoricain et l'ibérique. Ces deux traductions (publiées par le journal portoricain El Nuevo Dia et l'espagnol El Pals) abordées à travers une analyse linguistique comparative, permettent de mesurer leur degré d 'adéquation et d'acceptabilité. En parallèle, elles montrent les mutations de l'espagnol par l'influence de l'anglais.
Efeitos da atividade física sobre desfechos de saúde mental: revisão rápida de revisões sistemáticas
Authors: De Melo Roberta Crevelário , Da Silva Letícia Aparecida Lopes Bezerra , De Araújo Bruna Carolina , Domene Fernando Meirinho , Da Silva Jessica de Lucca , Milhomens Laís de Moura , De Bortoli Maritsa Carla , Toma Tereza Setsuko , Barreto Jorge Otávio Maia
Published: June 2023

Objetivo: Sintetizar as evidências científicas sobre efeitos de AF na saúde mental. Métodos:  Realizou-se uma revisão rápida de revisões sistemáticas (RS) publicadas de 2017 a 2021, por meio de buscas em sete bases eletrônicas da literatura. A avaliação da qualidade metodológica das RS foi realizada com a ferramenta AMSTAR 2. Resultados: Esta revisão aborda os efeitos da AF em pessoas sem diagnóstico de transtornos mentais. Dezesseis RS foram incluídas, sendo classificadas como de confiança baixa e criticamente baixa. Observaram-se benefícios de exercícios aeróbicos, anaeróbicos, terapias complementares e atividades combinadas sobre desfechos clínicos e não-clínicos, em crianças, jovens, adultos e idosos. Eventos adversos relacionados a exercícios aeróbicos foram relatados em uma RS. Conclusões: Os resultados indicam que a AF pode ser benéfica à saúde mental e qualidade de vida de pessoas de todas as faixas etárias. No entanto, é necessário considerar as limitações metodológicas e a heterogeneidade dos estudos quanto a intervenções e populações estudadas.
Organotypic Models for Functional Drug Testing of Human Cancers
Authors: Huang Yu Ling , Dickerson Lindsay K. , Kenerson Heidi , Jiang Xiuyun , Pillarisetty Venu , Tian Qiang , Hood Leroy , Gujral Taranjit S. , Yeung Raymond S.
Published: June 2023

In the era of personalized oncology, there have been accelerated efforts to develop clinically relevant platforms to test drug sensitivities of individual cancers. An ideal assay will serve as a diagnostic companion to inform the oncologist of the various treatments that are sensitive and insensitive, thus improving outcome while minimizing unnecessary toxicities and costs. To date, no such platform exists for clinical use, but promising approaches are on the horizon that take advantage of improved techniques in creating human cancer models that encompass the entire tumor microenvironment, alongside technologies for assessing and analyzing tumor response. This review summarizes a number of current strategies that make use of intact human cancer tissues as organotypic cultures in drug sensitivity testing.
(Global) Democracy: Present and perspectives
Authors: Rossetti Andrés
Published: June 2023

The text investigates the use of the concept of democracy in current times, particularly in its versions that associate it with its implementation in the global sphere. It starts from the question about the possibility of "talking" about democracy in certain conditions and circumstances and its confrontation with the reality. It is from a specific event that was the coup d'état that took place in Bolivia in 2019 -not recognized as such by a large part of the international community and academia- that the author analyzes the possibilities and perspectives of implementing a democratic system at the planetary. From the current reality, with the exceptional Covid-19 pandemic that has conditioned many aspects and with the stable neoliberalism that dominates the planet, the article analyses the conditions to achieve societies -in various fields- with higher levels of participation and equality that are the essential elements to characterize those societies to be considered as democratic.
What judges should a Democratic State have?
Authors: Ribotta Silvina
Published: June 2023

In the modern Democratic States, the people who end up being part of the judiciary as judges at different levels of justice are not representative of the diversity of society. Some people, their interests, and their conceptions of justice are overrepresented, while large societal sectors are underrepresented. This is even worse in societies that are more unequal. Furthermore, the training in human rights that the Schools of Law provide is deficient, both in the internal Law of Human Rights and International Human Rights Law, as well as in the procedures for the application of these in domestic justice and in the perspective of analysis and interpretation of general Law from Human Rights. This inadequate training is not corrected in the selection processes of the judiciary nor in training during the exercise. The article aims, from these analyses, to make visible the inegalitarian biases in the composition of justice administrations, the inadequate training they have in Human Rights, and how this situation affects the reproduction of social injustices. Furthermore, proposes the implementation of specific public policies that could be effective on the strengthening of democracy and the modern Constitutional State.
ANALISIS PERBUATAN OBSTRUCTION OF JUSTICE YANG DILAKUKAN OLEH APARAT KEPOLISIAN DALAM PERKARA PEMBUNUHAN BERENCANA
Authors: Shallom Jeremiah Keren , Hasiyanni Manurung Karina
Published: May 2023

Kasus mengenai Obstruction Of Justice menjadi perbincangan hangat di tengah masyarakat. Kini permasalahan yang menyangkut dengan aparat penegak hukum yakni kepolisian terus menjadi sorotan masyarakat dan membuat masyarakat bertanya-tanya seperti bagaimanakah peranan serta penegakan hukum yang menjadi salah satu delik tindakan terjadinya Obstruction Of Justice di dalam kasus pembunuhan berencana dan bagaimanakah hubungan antara aturan kepolisian terhadap anggota kepolisian lainnya yang turut memeriksa dari perbuatan Obstruction Of Justice dalam perkara pembunuhan berencana ini. Tujuan dari penulisan ini yakni untuk menganalisis serta mengetahui adanya permasalahan penghilangan terhadap alat bukti di dalam kasus pembunuhan berencana yang dilakukan oleh para oknum apa kepolisian yang akhirnya berujung sebagai tindakan Obstruction Of Justice. Hasil penulisan ini menegaskan bahwa perlu adanya ketegasan dalam menerapkan sanksi pidana untuk menjalankan anggota kepolisian yang melakukan Obstruction of Justice dalam pasal pembunuhan berencana.

Kata Kunci: Penghalang Keadilan, Pembunuhan Berencana, Sanksi Pidana
USO DE ANTIDEPRESSIVOS NA INFÂNCIA E ADOLESCÊNCIA
Authors: Alves Gomes Germana , Eduardo Ferreira Francisco , Laurindo Alexandra , Alves Moreira Jéssica
Published: May 2023

RESUMO: Introdução: A depressão é representada por desânimos e tristeza profunda, que atinge a população em qualquer faixa etária, sendo caracterizada por transtorno psiquiátrico, quando acometidos em jovens e crianças são impactados por formas graves, realizando uma consequência negativa no comportamento social, escolar e familiar desse grupo. Objetivos: Analisar o uso de antidepressivos em pacientes da faixa etária infantil e adolescente e seus efeitos colaterais. Metodologia: A presente pesquisa trata-se de uma revisão integrativa; as bibliotecas utilizadas para busca serão: a Biblioteca Virtual em Saúde (BVS), através da base de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS); a Scientific Eletronic Library Online (ScIELO) e o PubMed. A busca realizar-se-á entre os meses de janeiro a maio de 2023, utilizando-se as seguintes palavras-chave: Depressão, Uso de antidepressivos, Saúde mental, Adolescente e Infância. A busca limitar-se-á a estudos em seres humanos, redigidos em português, e que tenham sido publicados nos últimos 10 anos. Resultado e Discussões: Ao todo foram selecionados 12 artigos de revisão, (n= 2 na LILACS, N= 4 BVS e 6 na SCIELO). As publicações caraterizadas como livros, teses, dissertações e TCC foram retiradas. A farmacoterapia é uma parte importante do tratamento da depressão na criança e no adolescente. Ela deve fazer parte de uma estratégia terapêutica mais ampla, pautada em uma exaustiva avaliação psiquiátrica da criança. Conclusão: Na literatura, ainda são poucos os estudos e investigações sobre a eficácia e segurança dos antidepressivos em crianças e adolescentes.

Palavras-Chaves: Depressão; Uso de antidepressivos; Saúde mental; Adolescente; Infância.
Kajian Tafsir Lisan tentang Kata Shift Pemuda "Hijrah" Menurut Ustadz Teuku Hanan Attaki di Instagram
Authors: Ningsih Bunga Surawijaya , Hasanah Iezzatul , Na'im M. Devan Ainun
Published: May 2023

The occurrence of hijrah at the time of Prophet Muhammad is an event that cannot be forgotten in the hearts and hearts of all Muslims. Because this incident has a very high value in the history of the Islamic world. There are also many things that can be used as lessons. This study examines oral interpretation in the media on Instagram with a study on Ustadz Teuku Hanan Attaki (UHA). The main research question is how is UHA's verbal explanation of the word youth hijrah in the Qur'an and also what is the significance of UHA's oral interpretation of the word shift of youth hijrah in the Qur'an on Instagram. This approach uses a descriptive qualitative approach. The results of this study show that UHA in the interpretation of hijrah is to interpret QS. al-Muzzammil (74):10. In some commentaries, in general hijrah means an order to leave something because of displeasure, the command in this verse is accompanied by the sentence hijran jamilan, which means "in a good way" forbidden to work that is lawful, such as avoiding usury. In addition, UHA's oral interpretation of hijrah has a significance that is not in the written interpretation. It means that the oral interpretation of UHA' Hijrah is more acceptable to the audience because the interpretation is clearer at the moment.
Privasi dalam Dunia Digital (Analisis QS. An-Nur (24): 27 Menggunakan Pendekatan Ma’na-Cum-Maghza)
Authors: Fikri Khairul , Firdausiyah Umi Wasilatul
Published: May 2023

Abstract: Problems that still often arise in social life today are ethical issues, especially in terms of maintaining privacy, both in the real world and in the virtual world (digital). Starting to lose awareness of asking for permission and waning understanding of the boundaries of privacy has the potential to cause various problems and even criminal acts in the future. So it is important to describe how the Qoran teaches adab isti'dzan (asking permission) to take moral values ​​and practice them in life. Through the ma'na-cum-maghza approach, this paper aims to analyze QS. An-Nur (24): 27 regarding how the Qoran talks about the ethics of asking for permission and its relation to maintaining privacy. This is done in order to prove that the Qoran is still shalih li kulli zaman wa makan (relevant for every time and place) and can be used as a reference in solving contemporary problems. The results of this study indicate that the Qoran through QS. An-Nur (24): 27 not only prohibits entering the house without the permission of the owner, but it can also be understood in the current context that it contains a prohibition not to disturb other people's personal data in the digital world so thatcyber crimecan be avoided.
Evaluation of employees' experiences in the industrial training program in the polytechnic department of Iranian industries
Authors:   Master of Public Administration at Payam Noor Mahdasht University, Iran, Azimi Hossein
Published: May 2023

Purpose: Industrial training is a program that aims to provide supervised training within a particular time frame which can be carried out either in the private sector or in government organizations. Research methodology: The data were analyzed using a statistical package for prediction. Results: It was observed from the view of the lecturers that industrial training improved the student’s skills in formal and informal communication, help to find a research area for their projects, and ability to socialize, and sustain the relationship. In the view of the Employees, we observed that industrial training improved the Employees’ confidence in tackling problems and provides the need for continuous learning. Also, we observed that safety was the major challenge Employees faced during their internship. Limitations: The practical and usable environment for the results of this study is the educational environment. Contribution: We concluded that industrial training help to improve the student’s ability and knowledge after their training program. We recommended that industrial training should be seen as a tool to improve Employees’ abilities.
Evaluation of Wild Almond Genotypes Grown as a Rain-fed Crop in Sulaimani Governorate using RAPD and ISSR Markers
Authors: Mahmood Anwar Mohammed Raouf , Faraj Jamal Mahmood , Sharef Ashtekhwaz Ahmad , Majeed Hoshman Omar , Hamasalih Fakhraddin Mustafa , Tahir Nawroz  Abdul-razzak
Published: June 2023

Almond is considered the most common and essential nut grown in the rainfed area. It has many species wildly distributed in the Iraqi Kurdistan region, which are called Chaqala by local people. To understand and improve the characteristics of the cultivated almonds, a comprehensive study of wild almonds in terms of population structure and genetic diversity is needed to transfer new traits into the domesticated almonds. So, twelve different genotypes were collected and analyzed using random amplified polymorphic DNA (RAPD) and inter-simple sequence repeat (ISSR) markers. The results revealed polymorphic bands for both markers, the mean value of 5.8 for the RAPD marker and 7.8 for the ISSR marker was also documented. The polymorphic information content (PIC) values were obtained for RAPD primes that range between (0.64-0.85) and ISSR primers were also verified between (0.53-0.91), which shows the discriminatory power of these markers. “Jaccard similarity coefficients” were obtained between 0.34 (G11 vs. G12) to 0.77 (G1 vs. G10), and clustered into four groups with a mean similarity (0.65) for ten RADP markers. For ten ISSR markers, 0.35 (G8, G10) to 0.79 (G6 vs. G11) were also observed, which is clustered into a mean similarity (0.65). Structure analysis of RAPD and ISSR showed two major groups. Overall, these outcomes showed the diversity between the studied genotypes and among groups which are highly important for future almond breeding and conservation programs.
EEG Based Biometric Authentication System Using Multivariate FBSE Entropy
Authors: Kamaraju Sai Pranavi , Das Kritiprasanna , Pachori Ram Bilas
Published: May 2023

Data privacy and security are severe concerns in our world today. A broad range of biometrics relies on physiological traits, including fingerprints, iris scans, and facial recognition for authentication. Conventional methods like signatures, passwords can easily be spoofed. We have proposed a framework for biometric identification using electroencephalogram (EEG) signals recorded during signing, as an individual can not replicate another individual's signals. Multivariate variational mode decomposition (MVMD) is applied on EEG signals to extract properly aligned oscillatory modes from multi-channel EEG data. Features are extracted using Fourier-Bessel series expansion-based (FBSE) entropies. We have extended the univariate entropy for multi-channel signals, namely, multivariate FBSE-based entropy (M-FBSE-E). The M-FBSE-E is applied for feature extraction from the EEG signals. Machine learning-based classifiers are utilized to identify the EEG signals corresponding to original and forged signatures. We have collected a database from a reasonable number of participants to validate our proposed model. The proposed method achieved an average accuracy of 93.4$\pm$7.0\% for subject-wise EEG-based biometric identification for the fine K-nearest neighbor (KNN) classifier. The subject-independent EEG-based biometric identifier provides  89.4$\pm$1.9\% average accuracy when cosine KNN classifier is used. Experimental results show the effectiveness of the proposed framework for EEG-based biometric identification.
A new information tool as an enabling technology: application and simulation
Authors: Ciampa Francesca , Musarella Caterina Claudia
Published: May 2023

The research aims at identifying an information tool for design activities through enabling technologies, developed on the interactions between envelope and context. The methodology, articulated according to the phases of analysis, processing, and applicative validation, prefigures a response strategy to the phenomena of environmental and energy crisis with respect to the different scales of action. Considering the effect of climatic phenomena on the envelopes and the contemporary performance requirements they are called to meet, the contribution provides a dynamic data sheet (analysis and evaluation of energy-environmental performance) based on the model drawn up by the European Joint Research Centre, to verify the appropriateness of envelope design.
Enabling technologies to support energy transition in social housing
Authors: Gaspari Jacopo , Antonini Ernesto , Marchi Lia
Published: May 2023

Housing plays a key role in the world path to energy transition, and retrofitting buildings is a major asset to this end. Unfortunately, despite the supporting measures and incentives promoted in many countries, the renovation rate is still too slow. This is even more complex within some specific assets, such as social housing, which, especially in Italy, depends on the availability of public funds. The study proposes a predictive tool conceived as an enabler in the decision-making process, capable of considering and comparing the performance levels that different retrofitting actions can reach, according to building features, intervention costs, timing, and resource availability. The tool is tested on a social housing case study in Bologna.
Weeds Classification using Convolutional Neural Network Architectures
Authors: Suriya S , A Hema
Published: June 2023

Agriculture is an important sector for both human survival and economic growth. It has to be managed efficiently. This can be done by the use of technology in order to minimize human effort. It can be managed efficiently by following crop management tasks. One such crop management task is the identification and removal of weeds. Weeds are considered to be plants which are not required to be grown with the agricultural crops, because the weeds also utilize the water and nutrients like the agricultural crop and cause impact on the growth of agricultural crops. In order to identify weeds, deep learning technology can be used. The proposed system helps to classify weeds using Convolutional Neural Networks. This system employs models like, ResNet50, MobileNetV2 and InceptionV3, which are used for better classification. The system is evaluated based on these models, and all the three models have resulted in better accuracy.
Double Acceptance Sampling Plan for Odd Generalized Exponential Log-logistic Distribution Based on Truncated Life Test
Authors: D.C.U. Sivakumar , Gadde Srinivasa Rao , K Rosaiah , K Kalyani
Published: June 2023

According to the results of industrial research, product failure time is correlated with fatigue weakness, which is typically produced by repeated stress variations. A double acceptance sampling strategy was presented for shortened life tests where the lifespan of test products follows an odd generalized exponential log-logistic distribution (OGELLD), according to the findings of this study. The minimum sample sizes for the first and second samples are calculated using a producer’s risk of 0.05 to ensure that the actual median life is greater than the specified life at the chosen consumer confidence level. Based on various ratios of genuine median life to stipulated life, we analyzed operational features; we observed that reduced producer risk at the defined level was associated with the lowest median ratios to the specified level. Finally, an illustration is offered to help in the grasp of the suggested framework.
Towards the Adoption of Non-conventional Water Resources (Green and Grey Condensation): The Case of Egypt
Authors: Gnedy Amr Gomaa , Daoud Ahmed Osama , Elmansy Yahya
Published: June 2023

This research evaluates the dependency between air conditioner water and rainwater as a solution to water scarcity in Egypt. A sample from rain and air conditioner water has been collected in Cairo for lab testing. Also, an experiment involving a 1-tonne air conditioner has been conducted to estimate the volume of output water from the air conditioner. Moreover, a study of the meteorological data of El Shorouk City and the potential for water capture and reuse have been estimated. The British University in Egypt (BUE) has been taken as a case study to evaluate the amount of water per year that can be generated if the aforementioned two water sources are used. The lab testing results of rain and air conditioner water indicated that both had a slightly acidic nature with low mineral content. However, both samples meet standards for irrigation of crops and non-potable uses set by the Egyptian Decree of Health Ministry (No. 458) (2007). As for BUE, the amount of water that may be collected from air conditioners and rainfall was estimated at 1523.45 m³ and 8065 m³ per year, respectively. This water may be used for irrigation of green areas, distilled water for soil and concrete labs, or cleaning purposes.
Wartość technologiczna ziarna ozimej pszenicy twardej odmiany Komnata w zależności od sposobu chemicznej ochrony roślin
Authors: Spychaj Radosław , Gil Zygmunt , Chrzanowska-Drożdż Barbara
Published: May 2023

W pracy oceniono wpływ sposobu chemicznej ochrony roślin na właściwości ziarna i mąki ozimej pszenicy twardej odmiany Komnata. W latach 2005–2008 w RZD Pawłowice, należącym do Uniwersytetu Przyrodniczego we Wrocławiu przeprowadzono ścisłe doświadczenie polowe w 4 powtórzeniach, na glebie kompleksu pszennego dobrego, w stanowisku po rzepaku ozimym. W doświadczeniu polowym zastosowano trzy sposoby chemicznej ochrony roślin oraz poziom kontrolny, w którym nie stosowano środków ochrony roślin przeciwko patogenom wywoływanym przez grzyby. Uzyskane ziarno oceniono pod względem cech fizycznych, przemiałowych oraz cech jakościowych mąki, według metodyki obowiązującej w przetwórstwie pszenicy twardej. Uzyskane wyniki badań wykazywały znacznie większy wpływ warunków pogodowych na cechy ziarna i mąki ozimej pszenicy twardej niż sposobu chemicznej ochrony roślin. Ziarno o najkorzystniejszych cechach jakościowych otrzymano w 2006 roku, w którym w lipcu, podczas dojrzewania pszenicy odnotowano bardzo niską sumę opadów (12 mm), a temperatura przekraczała o prawie 5°C średnią wieloletniej z lat 1976–2005. Wartość współczynnika Sielinianova (k) dla tego okresu wyniosła tylko 0,16. Sposób chemicznej ochrony roślin, polegający na zaprawianiu ziarna siewnego i dwukrotnym stosowaniu fungicydów, sprzyjał uzyskaniu ziarna o najlepszych cechach jakościowych za wyjątkiem wartości wskaźnika wielkości cząstki. Wpływ badanego czynnika na cechy przemiałowe ziarna za wyjątkiem wydajności mąki śrutowej i wymielności kaszek był nieistotny, natomiast w odniesieniu do cech jakościowych mąki powodował jedynie obniżenie rozpływalności glutenu.
Zmodyfikowana technika pojedynczego ziarna w hodowli jęczmienia ozimego
Authors: Surma Maria , Adamski Tadeusz , Kuczyńska Anetta , Krystkowiak Karolina , Trzeciak Renata , Mikołajczak Krzysztof , Ogrodowicz Piotr
Published: May 2023

Technika pojedynczego ziarna (ang. single seed descsent, SSD) jest coraz częściej stosowana do uzyskiwania form homozygotycznych w hodowli zbóż. Stanowi ona modyfikację klasycznego ramszu i polega na losowym wyborze w każdym pokoleniu, począwszy od F2, po 1 ziarnie z rośliny. W pokoleniu F5 lub dalszym zbiera się wszystkie nasiona z rośliny; potomstwo pojedynczej rośliny stanowi linię SSD. Praca przedstawia modyfikację techniki SSD polegającą na połączeniu jej z kulturą in vitro niedojrzałych zarodków. Pozwala to wyeliminować okres spoczynku nasion i tym samym przyspieszyć cykl hodowlany. Wykazano, że stosując zaproponowaną technikę można w ciągu pierwszych trzech lat przyspieszyć cykl hodowli jęczmienia ozimego o 2–3 lata.
Przechowywalność sześciu odmian ziemniaka uprawianych w latach 2007–2009
Authors: Czerko Zbigniew
Published: May 2023

Celem doświadczenia była ocena wielkości strat nowych odmian (Benek, Bellarosa, Ewelina, Meridian, Miłek, Owacja), określenie terminów rozpoczęcia kiełkowania ziemniaków przechowy-wanych w temperaturach 3°C, 5°C i 8°C oraz poszukiwanie wpływu czynników pogodowych w okresie wegetacji na termin rozpoczęcia kiełkowania, ubytków naturalnych i chorób przechowal¬niczych podczas przechowywania. Po przechowywaniu w temperaturach 3°C, 5°C, 8°C określono ubytki naturalne, straty wywołane rozwojem chorób oraz kiełkowaniem. Średnio, ubytki naturalne ziemniaków przechowywanych w temperaturze 3°C i 5°C były na tym samym poziomie (6,1% i 6,4%). Ziemniaki przechowywane w wyższej temperaturze 8°C miały istotnie wyższe ubytki naturalne (7,2%) niż przechowywane w temperaturze 3°C i 5°C. Średnie straty spowodowane rozwojem chorób przechowalniczych wynosiły dla poszczególnych odmian od 0,20% do 1,23% i tylko odmiana Benek miała straty przekraczające 1,0%. Początek kiełkowania zależał od odmiany, temperatury przechowywania i warunków wegetacji. Rozpoczęcie kiełkowania ziemniaków przechowywanych w 8°C zależało od odmiany i nastąpiło w 1 dekadzie grudnia (Meridian) a najpóźniej w 1 dekadzie lutego (Bellarosa). Kiełkowanie ziemniaków przechowywanych w 3oC powodowało opóźnienie rozpoczęcia kiełkowania o 7 dekad w porównaniu do przechowywania w 8°C. Warunki wegetacji miały wpływ na termin rozpoczęcia kiełkowania, ubytki naturalne i choroby podczas przechowywania.
Extremt
Authors: Robertsson Marianne
Published: June 2023

Recension av: Extremt. Etnologiska analyser av kvinnorock, extremsport och Ultimate Fighting 2007. Red. Anna-Maria Ånäs, Lotta Wessberg och Anna-Maria Åström. Åbo: Åbo Akademis förlag 2007 (Etnologi vid Åbo Akademi rapport 12.), 208 s., ill.
Om mediernas makt att invandrargöra
Authors: Illman Ruth
Published: June 2023

Recension av: Ericsson, Urban 2007: Belägrade människor – belägrade rum. Om invandrargöranden och förorter. (Etnolore 30, Skrifter från Etnologiska avdelningen.) Uppsala universitet, Uppsala, 194 s.
Välkommen till paradiset
Authors: Jofs Camilla
Published: June 2023

Recension av: Jennie Dielemans & Shahab Salehi 2008: Välkommen till paradiset. Reportage om turistindustrin. Stockholm: Atlas. 272 s, ill.
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Avsked och återseende
Authors: Niemitalo Pia-Maria
Published: June 2023

Recension av: Hagmark-Cooper, Hanna 2008: Avsked och återseende. Sjömanshustruns liv under 1900-talet. Helsingfors: Svenska litteratursällskapet i Finland, 171 s.
Isorokko vuoden 1918 Urjalassa
Authors: Pirhonen Lotta
Published: June 2023

Vuosina 1918–1919 esiintyi Suomessa poikkeavan korkeaa kuolleisuutta, johon olivat syinä sisällissota, poikkeusoloista johtuva ravinnon puute, monet kulkutautiepidemiat, lääkkeiden ja lääkärien vähyys ja rokotussuojan puutteet. Yksi vakavista ja paljon kuolleisuutta aiheuttavista kulkutaudeista oli isorokko. Tämä katsaus käsittelee isorokkoepidemiaa Pirkanmaalla Urjalassa vuonna 1918. Tarkastelen aihetta kirjallisuuden lisäksi Urjalan vuoden 1918 kunnalliskertomuksen, Tammelan piirilääkärin arkiston ja vuoden 1918 Urjalan Sanomien avulla.