bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetics Contributes to Concomitant Pathology and Clinical Presentation in Dementia with Lewy Bodies
Authors: van der Lee Sven J. , van Steenoven Inger , van de Beek Marleen , Tesi Niccolò , Jansen Iris E. , van Schoor Natasja M. , Reinders Marcel J.T. , Huisman Martijn , Scheltens Philip , Teunissen Charlotte E. , Holstege Henne , van der Flier Wiesje M. , Lemstra Afina W.
Published: July 2021

Background: Dementia with Lewy bodies (DLB) is a complex, progressive neurodegenerative disease with considerable phenotypic, pathological, and genetic heterogeneity. Objective: We tested if genetic variants in part explain the heterogeneity in DLB. Methods: We tested the effects of variants previously associated with DLB (near APOE, GBA, and SNCA) and polygenic risk scores for Alzheimer’s disease (AD-PRS) and Parkinson’s disease (PD-PRS). We studied 190 probable DLB patients from the Alzheimer’s dementia cohort and compared them to 2,552 control subjects. The p-tau/Aβ1–42 ratio in cerebrospinal fluid was used as in vivo proxy to separate DLB cases into DLB with concomitant AD pathology (DLB-AD) or DLB without AD (DLB-pure). We studied the clinical measures age, Mini-Mental State Examination (MMSE), and the presence of core symptoms at diagnosis and disease duration. Results: We found that all studied genetic factors significantly associated with DLB risk (all-DLB). Second, we stratified the DLB patients by the presence of concomitant AD pathology and found that APOE ɛ4 and the AD-PRS associated specifically with DLB-AD, but less with DLB-pure. In addition, the GBA p.E365K variant showed strong associated with DLB-pure and less with DLB-AD. Last, we studied the clinical measures and found that APOE ɛ4 associated with reduced MMSE, higher odds to have fluctuations and a shorter disease duration. In addition, the GBA p.E365K variant reduced the age at onset by 5.7 years, but the other variants and the PRS did not associate with clinical features. Conclusion: These finding increase our understanding of the pathological and clinical heterogeneity in DLB.
Influence of Privacy Fatigue of Social Media Users on Their Privacy Protection Disengagement Behaviour—A PSM based Analysis
Authors: Zhang Xiaojuan , Tian Xinluan , Han Yuxin
Published: July 2021

This paper aims to examine the net effect of privacy fatigue of social media users on privacy protection disengagement behaviour, which is helpful to address the users’ privacy issue in the new stage of social media digitalization. Applying the Propensity Score Matching (PSM) methodology, the authors conduct the data analysis of 1,734 samples of social media users and eliminates the selectivity error caused by individual characteristic variables so as to improve the prediction accuracy of variable causality. Their research not only validates the causal relationship between privacy fatigue and privacy protection disengagement, proving that privacy fatigue can directly lead to privacy protection disengagement behaviour but also reveals that the individual characteristic variables have heterogeneous effects on the influence of privacy fatigue on protection disengagement behaviour.
Interpolation functions of interval type-2 fuzzy systems
Authors: Zhao Shan , Li Zhao
Published: July 2021

The interpolation functions of interval type-2 fuzzy systems and their universal approximation are investigated in this paper. Two types of fuzzification methods are designed to construct the antecedents and consequents of the type-2 inference rules. Then the properties of the fuzzy operator and the type-reduction algorithm are used to integrate all parts of the fuzzy system. Interpolation functions of interval type-2 fuzzy systems, which are proved to be universal approximators, are obtained based on three models, namely single input and single output, double inputs and single output, and multiple inputs and single output. The proposed approach is applied to approximate experiments of dynamic systems so as to evaluate the system performance. The system parameters are optimized by the QPSO algorithm. Experimental results for several data sets are given to show the approximation performances of the proposed interpolation functions are better than those of the interpolation function of the classical type-1 fuzzy system.
Neutrosophic three-way concept lattice and its application in conflict analysis
Authors: Yang Han , Qin Keyun
Published: July 2021

The theory of three-way concept analysis has been developed into an effective tool for data analysis and knowledge discovery. In this paper, we propose neutrosophic three-way concept lattice by combining neutrosophic set with three-way concept analysis and present an approach for conflict analysis by using neutrosophic three-way concept lattice. Firstly, we propose the notion of neutrosophic formal context, in which the relationships between objects and attributes are expressed by neutrosophic numbers. Three pairs of concept derivation operators are proposed. The basic properties of object-induced and attribute-induced neutrosophic three-way concept lattices are examined. Secondly, we divide the neutrosophic formal context into three classical formal contexts and propose the notions of the candidate neutrosophic three-way concepts and the redundant neutrosophic three-way concepts. Two approaches of constructing object-induced (attribute-induced) neutrosophic three-way concept lattices are presented by using candidate, redundant and original neutrosophic three-way concepts respectively. Finally, we apply the neutrosophic formal concept analysis to the conflict analysis and put forward the corresponding optimal strategy and the calculation method of the alliance.
Deep spatio-temporal emotion analysis of geo-tagged tweets for predicting location based communal emotion during COVID-19 Lock-down
Authors: Amsaprabhaa M. , Nancy Jane Y. , Khanna Nehemiah H.
Published: July 2021

Due to the COVID-19 pandemic, countries across the globe has enforced lockdown restrictions that influence the people’s socio-economic lifecycle. The objective of this paper is to predict the communal emotion of people from different locations during the COVID-19 lockdown. The proposed work aims in developing a deep spatio-temporal analysis framework of geo-tagged tweets to predict the emotions of different topics based on location. An optimized Latent Dirichlet Allocation (LDA) approach is presented for finding the optimal hyper-parameters using grid search. A multi-class emotion classification model is then built via a Recurrent Neural Network (RNN) to predict emotions for each topic based on locations. The proposed work is experimented with the twitter streaming API dataset. The experimental results prove that the presented LDA model-using grid search along with the RNN model for emotion classification outperforms the other state of art methods with an improved accuracy of 94.6%.
A novel hybrid deep learning model for taxi demand forecasting based on decomposition of time series and fusion of text data
Authors: Zhu Kun , Zhang Shuai , Zhang Wenyu , Zhang Zhiqiang
Published: July 2021

Accurate taxi demand forecasting is significant to estimate the change of demand to further make informed decisions. Although deep learning methods have been widely applied for taxi demand forecasting, they neglect the complexity of taxi demand data and the impact of event occurrences, making it hard to effectively model the taxi demand in highly dynamic areas (e.g., areas with frequent event occurrences). Therefore, to achieve accurate and stable taxi demand forecasting in highly dynamic areas, a novel hybrid deep learning model is proposed in this study. First, to reduce the complexity of taxi demand time series, the seasonal-trend decomposition procedures based on loess is employed to decompose the time series into three simpler components (i.e., seasonal, trend, and remainder components). Then, different forecasting methods are adopted to handle different components to obtain robust forecasting results. Moreover, considering the instability and nonlinearity of the remainder component, this study proposed to fuse the event features (in particular, text data) to capture the unusual fluctuation patterns of remainder component and solve its extreme value problem. Finally, genetic algorithm is applied to determine the optimal weights for integrating the forecasting results of three components to obtain the final taxi demand. The experimental results demonstrate the better accuracy and reliability of the proposed model compared with other baseline forecasting models.
A novel grey model of impulse delay and its application in forecasting stock price
Authors: Duan Huiming , Huang Jiangbo , Wang Siqi , He Chenglin
Published: July 2021

The stock market is an important embodiment of a national economy and financial activities and has an important impact on a country, enterprises and individuals. Stock forecasting can allow investment institutions and investors to understand the trend of the stock market in advance, which is a challenging and meaningful study. First, through the impulse phenomenon of the stock market, this paper discusses the problem of stock price prediction with delay, and the impulse delay differential equation is established. Second, according to the difference between the differential and the difference, the nonlinear delay grey prediction model is established. Next, the model parameters are estimated and the solving steps are obtained. The nonlinear parameters and delay time are optimized by the particle swarm optimization algorithm. Finally, the new model is applied to the prediction of the Shanghai stock market and the Shenzhen stock market closing indexes; the results show that the new model can effectively predict stock prices, which is much better than the existing four grey models and a time series model.
New definition of MV-semimodules
Authors: Goraghani Simin Saidi , Ali Borzooei Rajab , Ahn Sun Shin
Published: July 2021

In recent years, A. Di Nola et al. studied the notions of MV-semiring and semimodules and investigated related results [9, 10, 12, 26]. Now in this paper, by using an MV-semiring and an MV-algebra, we introduce the new definition of MV-semimodule, study basic properties and find some examples. Then we study A-ideals on MV-semimodules and Q-ideals on MV-semirings, and by using them, we study the quotient structures of MV-semimodule. Finally, we present the notions of prime A-ideal, torsion free MV-semimodule and annihilator on MV-semimodule and we study the relations among them.
Mercury(II) chloride nonoccurrence in nature: A molecular-level investigation
Authors: Mousavi Aliyar
Published: July 2021

Prepared by Chinese alchemists in the first millennium A.D., mercury(II) chloride (HgCl2) has been known since the Middle Ages. However, as it has never been found in mercury mines, its nonoccurrence in nature appears to be a basic assumption. Electrochemical principles were applied to show that the secondary mineral calomel in mercury mines is partly converted to HgCl2 in a multistep natural process. This showed how HgCl2 does occur naturally, providing a theoretical basis for the detection and quantification of solid HgCl2 as a mineral in mercury mines.
Preparation of (mono)sulfonates: Suitable precursors for unnatural sulfonolipids
Authors: Ioannou Panayiotis V. , Tsivgoulis Gerasimos M.
Published: July 2021

Aiming at the preparation of the novel unnatural, non-isosteric sulfonolipids bearing one, two and three acyl groups 8, 9 and 10, their precursors hydroxyl-containing sulfonates have been prepared from a variety of hydroxyl-containing halogenides and epoxides using the Strecker reaction. Thus, the sulfonates 16 and 22 were prepared pure, while the sulfonate 27 could only be prepared as a by-product using 1,4-dibromo-2,3-butanediol 26 and in low yields. For these reactions, probable pathways leading to the isolated or spectroscopically identified products are proposed. Conclusions about the relative nucleophilicity of SO32- compared to AsO33 - (as well as HO- which is present in their aqueous solutions) were drawn based on the yields of the corresponding arsonic acids and sodium sulfonates. The IR (KBr) and 1H NMR (D2O) spectra of sulfonates (and in some cases of their sulfonic acids) are analyzed and discussed.
Asymmetric phthalocyanine compounds in the structure D-π-A containing cyano groups: Design, synthesis and dye-sensitized solar cell applications
Authors: Karadoğan Betül , Erden İbrahim , Berber Savaş
Published: July 2021

In this study, asymmetric zinc phthalocyanine compounds with Donor- π-Anchor (D- π-A) property that enable the movement of electrons in molecular structure in one direction were synthesized. Phthalocyanines were designed to ensure electron mobility within the molecule and to facilitate the transfer of electrons to the TiO2 layer. The synthesized asymmetric zinc phthalocyanines (ZnPc-1 and ZnPc-2) are molecules with three donor biphenyls and one anchor aldehyde group and three acceptor/anchor cyano and one anchor aldehyde group, respectively. The effect of biphenyl and cyano groups on cell efficiency with aldehyde anchor group was investigated. The structure of the synthesized phthalocyanines was characterized by Fourier Transform Infrared Spectrometry (FTIR), Mass Spectrometry (MS), UV-vis, Fluorescence spectroscopy. The experimentally calculated optical band gap values were supported by the values found by Density Functional Theory (DFT) calculations. dye sensitive solar cells were measured and the efficiencies were evaluated with reference to the N719 standard dye. In the solar cell measurements of the designed phthalocyanines, the structure containing the cyano group has been given a higher photovoltaic cell thanks to the higher short circuit photo-current (Jsc). In this way, the highest power conversion efficiency value was achieved among the cyano group molecules.
Synthesis, spectral and thermal characterization, biological activity of a new amino acide ester containing substituted salicylaldimine Schiff base ligand and its Ru(II)bipyridyl complex
Authors: Yörür-Göreci Çiğdem , Altaş-Puntar Nilay , Toraman Abdullah , Demirhan Nebahat
Published: July 2021

The new salicylaldimine, as O,N-bidentate ligand (HL), containing amino acide ester and its Ru(II) complex [Ru(bpy)2(HL)]Cl2 have been prepared. Synthesized compounds have been structurally characterized by IR, 1H NMR, LC-MS, fluorescence spectroscopy, elemental and thermal (TGA-DSC) analyses. The metal to the ligand ratio of the Ru(II) complex was found to be 1:1. Antifungal activities of the ligand and complex have been investigated. The Ru(II) complex have strong antifungal activity than the ligand against Aspergillus niger.
Peruvian Parents Perceptions of Children's Obesity
Authors: Trejo Kathleen M. , Shaw-Ridley Mary
Published: July 2021

Although parents are critical to childhood obesity prevention, little is known about Peruvian parents' perceptions regarding childhood obesity, a country undergoing an emerging obesity epidemic. The study assessed Peruvian parents' perceptions regarding their children's obesity risks and behaviors. The specific objectives were to: (a) assess the knowledge, attitudes, and behaviors of parents regarding nutrition and physical activity of their preschool-aged children, and (b) assess parents’ ability to recognize overweight status in their children. Methods: The cross-sectional study surveyed 202 parents of preschool children (Mean age= 49.4 months, SD = 8.5) in the peri-urban slum communities of Lima, Peru utilizing a modified version of the Behavior and Attitudes Questionnaire for Healthy Habits (BAQ-HH) questionnaire. Children's body mass index (BMI) was compared with parental descriptions of the child's weight. Results: Nearly half (41.3%) of children had exceeded healthy weight (defined as BMI- for-age Z- score >-2 and £1). Parents demonstrated high knowledge, positive behaviors, and concerned attitudes. Parental knowledge and attitude scores predicted parental behavior scores (p=0.004). More than half (56.6%) accurately perceived their child's weight. However, 90.4% of parents of overweight/obese children underestimated their weight. Conclusions: Understanding Peruvian parents' perceptions of their children's obesity risk is essential to planning comprehensive interventions.
PREDICTIVE VALUE OF SERUM PROSTATE SPECIFIC ANTIGEN IN DETECTING BONE METASTASIS IN PROSTATE CANCER
Authors: Danarto Raden , Astuti Indwiani , Haryana Sofia Mubarika
Published: July 2021

Objective: We determine the utility of Prostate Specific Antigen (PSA) for predicting the presence of skeletal metastasis on Bone Scan (BS) in prostate cancer patients. Material & Methods: Retrospective analysis of medical records of 70 consecutive prostate cancer patients subjected to bone scan during the last 2 years was done. 5 cases were excluded due to the following reasons: Serum PSA not available, hormonal or other therapy given prior to serum PSA measurement, and/or Bone Scan, and symptomatic for bone metastasis. In remaining 65 cases, PSA value and bone scan were evaluated. Results: BS was found to be positive in 20/65 (31%) and negative in 45(69%) patients. 24 (37%) had serum PSA > 100 ng/ml, 25 (38.5%) had PSA of 20‐100 ng/ml and only 16 (24.5%) had PSA < 20 ng/ml. Conclusion: Serum PSA < 20 ng/ml have high predictive value in ruling out skeletal metastasis. Our data are in corroboration with results from previous studies that BS should be performed only if PSA > 20 ng/ml. Using this cut‐off, unnecessary investigation can be avoided. Avoiding BS asymptomatic in this group of patients would translate into a significant cost‐saving and reduction in their psychological and physical burden.
RELATION OF TOTAL CHOLESTEROL TO PROSTATE VOLUME AND INTRAVESICAL PROSTATIC PROTRUSION IN BENIGN PROSTATIC HYPERPLASIA PATIENTS
Authors: Made Devi Desyana Arisandi  , Wahyudi Septa Surya , Fatmawati Heni
Published: July 2021

Objective: To determine the relationship between total cholesterol, prostate volume, and intravesical prostatic protrusion in patients with benign prostatic hyperplasia. Material & Methods: This study used a cross-sectional method, carried out at the Paru and Bina Sehat Hospital in Jember. The sample in this study was BPH patients who met the inclusion criteria taken through medical record data from October 2019 to January 2020 Results: Samples on this study amounted to 33 patients. In this study, there was a difference between normal and high cholesterol with prostate volume in BPH patients (p = 0.00) and there was a significant relationship between cholesterol and prostate volume with strong correlation strength (p = 0.00 and r = 0.751) while the difference between high and normal cholesterol with IPP obtained insignificant results (p = 0.211) and the correlation between cholesterol and IPP obtained an insignificant relation with weak correlation strength (p = 0.217 and r = 0.221). Conclusion: There is a significant relationship between total cholesterol and prostate volume and a significant difference in prostate volume between normal and high total cholesterol in BPH patients, while there is no significant result between total cholesterol and intravesical prostatic protrusion in BPH patients.
NEEDLE RENAL LIFTING TECHNIQUE IN MANAGEMENT OF COMPLICATED PROXIMAL URETERAL LITHOTRIPSY: A CASE REPORT
Authors: Risan Muhammad , Soeroharjo Indrawarman , Danarto Raden , Yuri Prahara
Published: July 2021

Objective: To described a needle renal lifting technique using an 18-gauge needle to adjunct ureterorenoscopy (URS) in the management of complicated proximal ureteral stones. Case(s) Presentation: A 46 years old man presented with right flank pain for 1 month. This patient was diagnosed with ureteral stone and ureteral kinking that prohibits access to the proximal side of the ureter. Due to difficult access to the proximal ureter, we perform a needle renal lifting technique which is initialized by puncturing the middle renal calyx with 18-gauge needle. Then, the proximal end of the needle was pushed to the caudal direction to move the kidney to the cephalic direction and straighten the kinked ureter. After that procedure, the URS sheat can easily enter the proximal ureter to the stone site. Discussion: The success rate of this procedure is based on the operator skills to access the calyx and perform URS simultaneously. Like a previous technique, needle renal lifting is effective only when the kidney is mobile. Conclusion: The needle renal lifting technique can be used to adjunct URS in the management of complicated ureteral stones which prohibited access to the proximal ureter.
THE EFFECTIVENESS OF TNF-Α INHIBITOR THERAPY IN BLADDER PAIN SYNDROME/INTERSTITIAL CYSTITIS PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Kholis Ahmad , Soetojo  , Djatisoesanto Wahjoe
Published: July 2021

Objective: To evaluate the effectiveness of TNF-α inhibitor therapy in Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC) patients compared to placebo, assessed using Global Response Assessment (GRA). Material & Methods: A systematic review and meta-analysis. Subjects were patients with moderate to severe diagnosis of BPS/IC who were given TNF-α inhibitor versus placebo, with the Global Response Assessment (GRA) (patient-reported self-reported BPS/IC treatment response scale). A systematic literature search was carried out on the English databases PubMed/MEDLINE and Science  Direct, published until September 2020. Data were extracted independently and assessed the bias and quality of each selected article. Results: Initially there were 124 studies. After further selection, 2 RCT studies were included in the criteria for this study. The number of samples obtained was 85 patients. There is 1 study that used 400 mg of certolizumab pegol subcutaneously and 1 study used adalimumab 80 mg subcutaneously and followed by 40 mg subcutaneously for 2 weeks. Both studies had statistically low heterogeneity with I2 = 0% (P = 0.34), so fixed effect statistical model was used to determine the result. Furthermore, there was no significant difference (P = 0.32) between the number of GRA responders from the TNF-α inhibitor and placebo therapy groups, with odds ratio of 1.61 (CI = 0.65-4.00). Conclusion: TNF-α inhibitor therapy did not increase GRA responders when compared to placebo.
Fundamentos para uma Política Nacional de Prevenção e Controle do Câncer
Authors: Kligerman Jacob
Published: July 2021

A execução das diversas políticas de controle de câncer, no mundo, depende consideravelmente do estágio de desenvolvimento de cada país e de suas particularidades territoriais, sócio-culturais e econômicas. O objetivo da política deve referir-se, simultaneamente, às questões relativas à incidência e à mortalidade por câncer. Com o esforço de gerações, desenhou-se para o Brasil uma PNPCC que, atualmente, exige formalização documental para se consolidar, após ser adequadamente apresentada, analisada, melhorada e divulgada nos foros pertinentes (a Comissão Intergestora Tripartite do SUS e o Conselho Nacional de Saúde, para começar).
Periodicidade de Realização do Exame Preventivo do Câncer do Colo do Útero
Authors: Instituto Nacional de Câncer
Published: July 2021

A realização do exame citopatológico de Papanicolaou tem sido reconhecida mundialmente como uma estratégia segura e eficiente para a detecção precoce do câncer do colo do útero na população feminina e tem modificado efetivamente as taxas de incidência e mortalidade por este câncer. A periodicidade trienal de realização do exame, estabelecida pelo Ministério da Saúde do Brasil, em 1988, e recomendada pelo Viva Mulher – Programa Nacional de Controle do Câncer do Colo do Útero e Mama, permanece atual e está em acordo com as recomendações dos principais programas internacionais.
Timolipoma gigante assintomático na infância: relato de caso
Authors: Vicuña Carlos Humberto , Roriz Walter , Torquato Emanuel , Gonçalves Alberto R , Faria Paulo , Toscano Edson
Published: July 2021

Reportamos o caso de uma tumoração volumosa localizada no mediastino anterior superior em uma criança do sexo feminino, negra, de 2 anos de idade. A paciente estava assintomática e não apresentava doenças associadas. Foi realizada avaliação pré-operatória usando a tomografia computadorizada e a ressonância nuclear magnética do tórax, que sugeriram o diagnóstico de timolipoma. Este tumor foi tratado cirurgicamente por uma toracotomia bilateral com secção transversa do esterno (incisão à Clamshell). O diagnóstico foi confirmado pela histopatologia. O timolipoma é um tumor raro do mediastino anterior que pode apresentar-se como uma grande massa em um paciente assintomático bem como associado com miastenia gravis, esclerose lateral amiotrófica, aplasia medular, hipogamaglobulinemia e liquen plano, entidades estas presentes principalmente nos adultos.
Emotion Regulation Strategies and Stress in Irish College Students and Chinese International College Students in Ireland
Authors: Sun Yuning , Nolan Conor
Published: July 2021

Little is known about the association between emotion regulation strategies and perceived stress in college students, and in particular the strategies used by international students. Present research examined if differences exist in the use of emotion regulation strategies between Irish college students and Chinese international students, and investigated the relationship between emotion regulation strategies and perceived stress in these two student populations. Chinese students reported more frequent use of cognitive reappraisal and expressive suppression compared to Irish students. There was a significant negative association between the habitual use of cognitive reappraisal and levels of stress in both Irish and Chinese students. There was a significant positive relationship between the habitual use of expressive suppression and levels of stress in Irish college students, but not in Chinese students. The findings highlight the importance of cultural context when investigating the association between emotion regulation strategies and perceived stress in students.
Conoscenza sui modi per prevenire e diffondere le STI tra gli studenti iscritti alle scuole statali nella città di Macapá, Amazônia, Brasile
Authors: Salviano Ana Laura Góes , Santana Giovanna Rocha , Dias Claudio Alberto Gellis de Mattos , Araújo Maria Helena Mendonça de , Oliveira Euzébio de , Dendasck Carla Viana , Santos Bruno Rodrigues dos , Fecury Amanda Alves
Published: July 2021

La sessualità ha iniziato ad essere vista come una portata positiva dell’azione umana, in questo contesto, ha iniziato a valorizzarsi l’educazione sessuale, sollevando discussioni sulla sua importanza. Lo scopo di questo articolo era quello di analizzare le conoscenze sulle forme di contagio e prevenzione delle STI. Questo studio è stato condotto in 03 scuole statali di livello elementare e secondario. Il campione era composto da 287 studenti regolarmente iscritti a queste scuole che coprivano l’8 ° grado / 7 ° grado della scuola elementare fino al 3 ° anno del liceo. I dati su sesso, età, stato civile, istruzione e altri sono stati raccolti in questo studio. La maggior parte dei partecipanti ha già avuto contatti con il termine STI; tuttavia, ha ancora credenze sulle sue forme di trasmissione. È necessario affrontare la sessualità con un aspetto più naturale e positivo della vita umana, fornendo la libera discussione di norme e modelli di comportamento e il dibattito degli atteggiamenti.
A Importância Do Enfermeiro Na Prevenção Do Câncer De Colo Do Útero
Authors: Nascimento Nathália de Souza Santos
Published: July 2021

Trata-se de um estudo sobre a importância do Enfermeiro na prevenção do câncer de colo do útero. O objetivo da pesquisa é discutir a efetividade do enfermeiro na promoção e prevenção do câncer de colo do útero, tendo como objeto de estudo, o Enfermeiro na prevenção. Utilizou-se como metodologia uma pesquisa bibliográfica com abordagem qualitativa, do tipo descritivo e exploratório. O câncer de colo do útero é uma lesão precursora no seu epitélio, mais precisamente na junção escamo colunar (JEC) sendo um grande problema de saúde atingindo toda a população mundial, pois apresenta alto índice de letalidade entre mulheres de várias idades. Pode-se concluir com este estudo, que a ação do enfermeiro como educador é primordial para a diminuição da incidência de mulheres acometidas pelo câncer cérvico-uterino, fazendo com que a mulher não tenha que realizar tratamentos para a cura do câncer, o que pode ser evitado com as atividades educativas e a realização do exame de Papanicolau. Ressalta-se ainda que é essencial inserir o homem e conscientizar a população dos benefícios de se prevenir contra as doenças precursoras como o HPV e o câncer de colo do útero, no sentido de minimizar a incidência da doença.
ВПЛИВ ГАЛУЗЕВО-РЕГІОНАЛЬНОГО АСПЕКТУ НА ПРОСТОРОВЕ ОРГАНІЗУВАННЯ ПІДПРИЄМНИЦЬКОЇ ДІЯЛЬНОСТІ
Authors: Василюк Софія
Published: July 2021

Визначено, що важливим питанням сьогодення є економічне районування. Обґрунтовано, що вирішення цілої низки економічних задач тією чи іншою мірою пов'язане з економічним районуванням. Визначені характерні риси економічних територій. Доведено, що при визначенні економічного району правильний підхід буде тоді коли економічні території як такі, а також території ринків праці, вважатимуть своїм центром місто. Визначено, що сильні міста заохочують природній розвиток чинників субурбанізації, а слабші центральні міста мають на неї негативний вплив зі зростанням частки мешканців, що переселяються за межі центрального міста. Доведено, що територіально-галузевий аспект оцінки господарської діяльності дає змогу оптимізувати розміщення галузей національної економіки, яка базується на аналізі потреб країни загалом й окремих регіонів у певних видах продукції, наявності виробничих можливостей, трудових, енергетичних, паливних, сировинних ресурсів.
ПЕРСПЕКТИВИ СТВОРЕННЯ БІОТЕХНОЛОГІЧНОГО КЛАСТЕРА У ЛЬВІВСЬКІЙ ОБЛАСТІ
Authors: Василюк Софія
Published: July 2021

Обґрунтовано, що на сьогодні немає уніфікованого механізму формування того чи іншого типу кластерів, що породжує потребу оцінки перспективності та раціональності створення та ефективного управління кластерами в умовах економіки України. Доведено, що з погляду інвестиційної привабливості Львівщину можна охарактеризувати як регіон з розвиненою транспортною, інженерною та соціальною інфраструктурою, високим рівнем розвитку креативної індустрії та інноваційної активності. Визначено сильні і слабкі сторони створення біотехнологічного кластера у Львівській області. Виокремлено ключові завдання даного кластера. Доведено, що формування біотехнологічного кластеру у Львівській області обумовлено закономірностями галузевого розвитку регіональної економіки і на даному етапі зароджується за умов сприятливого сполучення низки чинників, що відкриває перспективи виходу на зовнішні ринки та сприятливого клімату співпраці між суб’єктами кластера.
УПРАВЛІННЯ ФІНАНСАМИ, ОРІЄНТОВАНЕ НА РЕЗУЛЬТАТ, ЯК ПІДХІД ДО СИНЕРГІЇ ІНСТРУМЕНТІВ ДЕРЖАВНОЇ ПОЛІТИКИ1
Authors: Бухтіарова Аліна , Пахненко Олена , Бєлова Інна
Published: July 2021

У статті узагальнюється міжнародна практика застосування підходів до управління державними фінансами, орієнтованого на результат. Проведена класифікація моделей управління державними фінансами, орієнтованого на результат, за ознаками виду стратегії реформування державного сектору; традицій застосування моделей управління фінансами; та умов інтегрування елементів орієнтованості на результат. Досліджена міжнародна практика впровадження управління державними фінансами, орієнтованого на результат, на прикладі Франції, США, Великобританії та Австралії. Спільними для всіх моделей управління фінансами, орієнтованого на результат, є такі позитивні ефекти: підвищення управлінської гнучкості, автономії державних організацій, а також фінансової гнучкості у досягненні поставлених цілей фінансової політики.
Lay person perceptions of marine carbon dioxide removal (CDR) – Working paper
Authors:   NORCE Norwegian Research Center, Veland Siri , Merk Christine
Published: July 2021

This working paper presents first insights on lay public perceptions of marine carbon dioxide removal (CDR) approaches. In seven focus groups, three in Germany and four in Norway (including one pilot) the researchers asked members of the lay public to share their views of the ocean and the effects of climate change, four CDR approaches, as well as their reflections on responsible research and innovation (RRI) of marine CDR. The four CDR methods were ocean iron fertilization, ocean alkalinity enhancement, artificial upwelling, and blue carbon management through restoration of coastal and marine ecosystems. In addition, respondents were asked to compare the four approaches. Our findings indicate that the public will be very supportive of blue carbon management irrespective of its actual carbon sequestration potential, due in part to the perceived bad state of marine ecosystems worldwide. Participants were skeptical whether any of the CDR approaches could have relevant effect on carbon sequestration and long-term storage; they reasoned about issues such as the ability to scale up treatments in time and space, unforeseen or unforeseeable effects on ecosystems in time and space, and the role of industry in the implementation process. They argued that despite the potential availability of marine CDR, industry and the general public should stop polluting behaviors and practices. Nevertheless, the participants universally agreed that further research on all four CDR methods should be pursued to better understand effects on climate, ecosystems, local communities, and the economy.
Identifikasi Citra Jenis Bunga menggunakan Algoritma KNN dengan Ekstrasi Warna HSV dan Tekstur GLCM
Authors: Salsabila Alifa , Yunita Rika , Rozikin Chaerur
Published: July 2021

Beragamnya jenis bunga yang ada serta memiliki spesies dan kemiripan pada setiap ragamnya, membuat para pecinta tanaman dan pembudi daya sulit untuk membedakan dalam penentuan jenis bunga, diperlukannya waktu yang sangat lama untuk mengetahui jenis bunga jika hanya mengandalkan panca indera saja. Penerapan algoritma K-Nearest Neighbor serta ekstrasi ciri terhadap warna dan tekstur sangat membantu dalam pengolahan citra untuk mengidentifikasi bunga menjadi lebih mudah dan mempersingkat waktu, dengan akurasi terbesar 71% menggunakan nilai K-7, identifikasi bunga berhasil dilakukan.
Comparison of Charge Nurses’ and Registered Nurses’ Perceptions of Management Functions in the Implementation of Supervision in Hospital
Authors: Febriani Nelly , Siregar Tatiana
Published: July 2021

Introduction: Different perceptions in the supervision process, part of the management functions of nurse manager, are at risk and have a bad impact, such as conflicts that will result in lack of motivation, communication barrier, and decreased performance and quality of services in the hospital.
Purpose: The purpose of the study was to compare the perception of the head of the room with the implementing nurse about the role and function of management in the implementation of supervision. Methods: This quantitative study was conducted on a population of 515 nurses, and 81 nurses were used as a sample (71 nurses and 7 room heads) which were selected by accidental sampling. The research tool is in the form of a questionnaire containing management functions in supervision. Data were analyzed using independent t-test.
Results: The results of this research did not show a significant difference between charge nurses’ and registered nurses’ perceptions of the management function in supervision, as indicated by the p-value> 0.025 (95% CI), p-value = 0.990 (planning), p-value = 0.957 (organizing), p-value=0.962 (staffing), p-value=0.508 (directing),
Conclusion: With actuating aspect that obtained p-value = 0.977 and controlling aspect that obtained p-value = 0.790, the conclusion of this research is there was no significant difference between charge nurses’ and registered nurses’ perceptions of management functions in supervision.
TACTIC FULFILLMENTS OF THREE CORRELATIONS FOR PROBLEM-SOLVING MAPS AND ANIMATED PRESENTATIONS TO ASSESS STUDENTS’ STOICHIOMETRY PERFORMANCES
Authors: Su King-Dow
Published: July 2021

This research focuses on students’ tactic assessments of 3 correlations with illustrated 2-step strategic map and animated presentations in stoichiometry. The participants were divided into 2 learning groups: the experimental and the control group by quasi-experimental approach. Most of all, experimental group participants have been contingent on critical performances of thinking capabilities in accordance with tactic fulfillments of 3 correlations helpfully. In contrast with statistic findings of post-tests, experimental group participants get more formulated goals of individual learning in answering 5 algorithmic and conceptual pairs of achievement test items than those of control group participants. Students’ shift of reasoning from model-based to case-based requires them to explore an effective mental cognition and responses for full-fledged performances of problem-solving skills. After tactic fulfillments for 3 study objectives of visualized developments, experimental group participants have upgraded a distinct learning accumulation and project-based feedback at their best learning performances. Key words: problem-solving, stoichiometry, three correlations, tactic fulfillments.
Yeast fungi of the genus Malassezia in dermatological diseases in animals
Authors: Arkhypenko A. , Ushkalov V.
Published: July 2021

The relevance of a comprehensive study of yeast fungi of the genus Malassezia and the development of modern methods for the diagnosis of diseases caused by small domestic animals. Infectious diseases of small domestic animals caused by yeasts have become a high priority in recent years among the problems of veterinary mycology. However, issues of diagnosis, therapy and prevention of yeast infections in small pets remain poorly understood. Difficulties in diagnosing Malassezia infections lead to the fact that in most cases these diseases remain undiagnosed, sick animals do not receive adequate therapy. Therefore, there is a clear need to develop affordable and practical diagnostic algorithms. Depending on the severity and location of the lesion, systemic or local antifungal drugs are used in combination with symptomatic treatment: antihistamines, antipruritic drugs. If necessary, antibiotic therapy is used and in case of using systemic antifungal drugs, hepatoprotectors are prescribed. Malassezia-associated dermatitis in animals is usually a secondary problem due to an underlying skin disease, such as allergic dermatitis (including atopic canine dermatitis and flea dermatitis), recurrent bacterial pyoderma, and endocrine diseases (especially hypothyroidism). The diagnosis of Malassezia-associated dermatitis should be based on a combination of clinical manifestations and microbiological analysis. Treatment is usually selected depending on such factors as: form (localized or generalized), general state of health of the animal, the main primary disease. A review of literature sources on this issue. The characteristics of different species of the genus Malassezia, which are present on the skin of domestic animals and have an etiological significance in the occurrence of diseases of small domestic animals. The localization of yeast fungi on the body of sick animals is described. In Ukraine, these diseases have not been purposefully studied, and the awareness of veterinarians and humane physicians about them remains unsatisfactory.
Key words: yeast, fungi of the genus Malassezia, dermatitis, otitis, infection.
Dynamics of hemostasiological parameters in cows during pregnancy, after birth and in obstetric, gynecological and orthopedic pathology
Authors: Vlasenko S. , Rublenko M. , Yeroshenko O.
Published: July 2021

It is established that the physiological course of the gestational process occurs with the intensification of coagulation processes in the hemostasis system with thrombophilia, which has a two–phase nature – from the first month of pregnancy to the seventh and in the period of 2–3 days to calving with a peak of hypercoagulation by 2–5 that day after birth. The activation of hemostasis components is correlated with a high level of natural anticoagulant protein C and increased fibrinolysis activity through tissue plasminogen activator, which is controlled by a high level of its type I inhibitor. The main hemostasiological criteria are the levels: in phase I – fibrinogen 4,9–6,1 g/l, soluble fibrin about 0,04 g/l, activated partial thromboplastin time 38,1–39,7 s, functionally inactive forms prothrombin 0,88 ± 0,2 mg/ml in the first month of pregnancy; in phase II – fibrinogen 5,1–7,0 g/l, soluble fibrin about 0,01 g/l, functionally inactive forms of prothrombin 0,17 ± 0,05 mg/ml and protein C 72,0 ± 1,4 % after childbirth. In obstetric and gynecological pathology, the hypercoagulable state is aggravated to consumption coagulopathy, which is reflected in high plasma levels of soluble fibrin – 0,064 ± 0,005 g/l, fibrin / fibrinogen cleavage products – 7,5 ± 0,4 μg/ml, functionally inactive forms of prothrombi. – 1,90 ± 0,34 mg/ml and inhibitor of tissue plasminogen activator type I – 45,8 ± 0,9 IU/ml at the lowest level of tissue plasminogen activator – 0,38 ± 0,08 IU/ml (according to the norms 1,1–1,3 IU/ml) and protein C deficiency – <70%. Hypercoagulation in pregnant cows with purulent– necrotic lesions of the extremities is exacerbated by more pronounced hyperfibrinogenemia, an increase in its metabolites by 2,7 times (p<0,05) and a decrease in the activity of F XIII by 1,3 times (p<0,05) and the amount in the blood of proteinase inhibitor α2–M – 1,6 times (p<0,05). At the same time, the hypercoagulation syndrome in cows with obstetric and gynecological pathology due to its comorbidity with orthopedic not only intensifies, which is expressed in an increase in the level of hyperfibrinogenemia by 1,2 times (p<0,05), reduction of general coagulation tests by 1,3–2,1 times (p<0,001) and a decrease in the activity of FXIII in 1,2–1,3 (p<0,05), but is complicated by a decrease in the antiproteinase potential of the blood in 1,6–1,8 times.
Key words: cows, pregnancy, obstetric, gynecological pathology, purulent-necrotic lesions in the area of fingers, hemostasiological indicators.
Vorganjska peć cave site in the context of the Northern Adriatic Neolithic
Authors: Sirovica Filomena , Mihelić Sanjin , Perhoč Zlatko , Philibert Sylvie , Kačar Sonja , Korić Martina
Published: July 2021

Vorganjska peć važno je prapovijesno pećinsko nalazište smješteno na padini brda Organ iznad Batomlja kraj Baške na otoku Krku. Sredinom 20. stoljeća ovo, kao i druga pećinska nalazišta na kvarnerskim otocima, počinje istraživati Vladimir Mirosavljević. Zahvaljujući rezultatima njegovih istraživanja Vorganjska peć, zajedno s Jami na Sredi na otoku Cresu te Velom špiljom na otoku Lošinju, postaje značajan izvor podataka o neolitiku Kvarnera i time neizostavni dio rasprava o tome razdoblju na istočnojadranskoj obali. Kako istraživanja nikad nisu u cijelosti objavljena, revizijsko arheološko iskopavanje provedeno je kao provjera davno prikupljenih podataka o načinima korištenja špilje tijekom prapovijesti. Rezultati istraživanja dali su uvid u stratigrafski slijed intaktnih prapovijesnih arheoloških depozita s nalazima koji pripadaju razdoblju ranoga i srednjega neolitika. Analiza stratifikacije i prikupljenih pokretnih arheoloških nalaza doprinosi širenju uvida u kompleksne mehanizme procesa neolitizacije istočnoga Jadrana te govori o nedvojbenom informativnom i interpretativnom značenju ovoga nalazišta za razmatranja problematike sjevernojadranskoga neolitika
Meningkatkan Keterampilan Servis Atas Dalam Permainan Bola Voli dengan Pendekatan Pembelajaran Drill
Authors: Taslim Zailan
Published: July 2021

This study aims to find out about the ability or skills of class V students of elementary school 132 Rejang Lebong in servicing volleyball can be improved through the learning method of drill. In accordance with these problems, this study uses Classroom Action Researchw hich is carried out in two cycles and in that cycle there are planning, action, observation/reflection, and reflection. The sample/subject of this study were students at elementary school 132 Rejang Lebong, totaling 19 students. In the final test, collect data from cycle 1 and cycle 2 using the service skill test instrument for volleyball. From several inter-cycle test result obtained learning outcomes data from cycle 1 and cycle 2 there has been an increase of between 40% to 90%. Based on the result of data analysis and discussion it can be concluded that the drill and play approach can improve the ability to service volleyball at elementary school 132 Rejang Lebong. It is recommended that sports educators can implement the drill and play approach, as they are proven to able to improve service learning outcomes for volleyball.
LEGAL MODELING AS A METHOD OF CIVIL RESEARCH
Authors: Golubtsov V.G. , Valeev D.Kh.
Published: July 2021

Introduction: the authors of the scientific works on civil law often refer to the use of legal modelling methods as the methodological basis of their work. However, from the text of the work it is not always clear where and for what reasons the above method was used by the researcher. This situation is largely caused by the lack of sufficient knowledge about the essence and possibilities of this scientific cognition method, as well as about the rules, situations and order of its use. Purpose: to reveal the contents and show the perspectives of using the legal modelling method for performing private law researches. Methods: the general scientific cognition methods were mainly used (analysis, synthesis, induction, deduction, comparison, description and others), along with the specific juridical methods (juridical-dogmatic method, legal modelling method and others). Results: the possibility and (in some cases) the necessity to use both the theoretical legal modelling method and the empiric legal modelling method was proved. The essence of two types of legal modelling was explained: of the normative-legal type and of the behavioural type which should be used in dialectical unity and interrelation. Three stages of legal modelling were identified: building a legal model; comparing the constructed model with the actual legal phenomenon; forecasting the prospects for the development of the legal phenomenon on the basis of the constructed model.