bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH KECERDASAN EMOSIONAL DAN PERILAKU BELAJAR PADA TINGKAT PEMAHAMAN AKUNTANSI PADA MAHASISWA AKUNTANSI FEB UWKS
Authors: Agustin Tyssa Amelia Vega , Wany Eva , Prayitno Budi
Published: May 2024

The contemporary work environment underscores the necessity of competition among individuals to enhance skills and expertise in specific fields. Therefore, this study aims to investigate the improvement in skills and expertise, particularly in the context of students' comprehension of accounting. The research focuses on accounting students in the Faculty of Economics and Business at Wijaya Kusuma University Surabaya (UWKS). Employing an associative and quantitative approach, the study utilizes an online questionnaire as the primary instrument for data collection from respondents. The research population includes 51 students, with a sample size of 51 individuals, and 36 respondents provided responses. Classical assumption tests, such as normality, multicollinearity, and heteroskedasticity tests, were applied, along with multiple linear regression for quantitative data analysis. Hypothesis testing involved partial t-tests, simultaneous F-tests, and coefficient of determination assessments. The analysis revealed that emotional intelligence and learning behavior variables each had a positive partial effect. Simultaneously, both significantly influenced students' comprehension levels, as evidenced by a significant F-value (33.338) and a Sig. value lower than 0.05. Thus, both partially and simultaneously, this research demonstrates that emotional intelligence and student learning behavior significantly impact the comprehension levels of students at the Faculty of Economics and Business (FEB) at UWKS.
PENGARUH KINERJA KEUANGAN TERHADAP HARGA SAHAM PADA PERUSAHAAN HEALTHCARE YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Afrida Fenny
Published: May 2024

This research aims to examine the influence of financial performance, measured by Return On Assets (ROA), Net Profit Margin (NPM), and Debt to Equity Ratio (DER), on the stock prices of Healthcare companies listed on the Indonesia Stock Exchange during the period 2021-2022. The study employs purposive sampling as the method and adopts a quantitative approach, utilizing secondary data. The results of the research, analyzed through multiple linear regression, indicate that ROA, NPM, and DER do not have a significant impact on stock prices for Healthcare companies listed on the Indonesia Stock Exchange during the period 2021-2022.
PENTINGNYA EKSPOSUR PERUSAHAAN SEKTOR ENERGI UNTUK MENEMPUH PENGUNGKAPAN EMISI KARBON
Authors: Khotimah Siti , Sari Shinta Permata
Published: May 2024

Carbon emission disclosure is one of the important components in the disclosure made  by a company. Its disclosure is required to assess the company's responsibility to the environment that will increase the value and reputation of the company. This study aims to examine the effect of media exposure, ISO 14001 certification, environmental performance, and auditor credibility on carbon emission disclosure. The population in   this study are companies listed on the Indonesia Stock Exchange in 2018-2022. The sample in this study are energy sector companies listed on the Indonesia Stock Exchange in 2018-2022 which are taken using purposive sampling technique and obtained 19 samples with 95 observations. The type of data used is secondary data. This research uses multiple linear regression analysis methods to analyse the hypothesis. Based on the results of regression analysis with a significance level of 5%, this study concludes that ISO 14001 certification and environmental performance have effect on carbon emission disclosure, while media exposure and auditor credibility have no significant effect on carbon emission disclosure.
THE PERCEPTIONS OF ISLAMIC BOARDING SCHOOL GUARDIANS, ACCOUNTING STUDENTS, AND NON-ACCOUNTING STUDENTS ON THE ETHICS OF PREPARING FINANCIAL STATEMENTS BASIS DE PSAK 112 (CASE STUDY OF ISLAMIC SCHOOLS IN PEKALONGAN)
Authors: Pribadi Tegar Hary
Published: May 2024

This research aims to examine the ethics of financial reporting based on PSAK 112 in the context of Islamic boarding schools (pondok pesantren) in Pekalongan. The ethical aspects considered include earnings management, misstatement, disclosure, cost and benefit, and responsibility in financial reporting. The study is conducted directly within the environment of Islamic boarding schools in both the city and regency of Pekalongan. The respondents include 113 caretakers of Islamic boarding schools, 70 accounting students, and 73 non-accounting students. The analytical tool applied for hypothesis testing (H1, H2, H3, and H4) is ANOVA. The findings of this research reveal that there is no significant differentiation in the perception of ethical practices in financial reporting among caretakers of Islamic boarding schools, accounting students, and non-accounting students. However, there is differentiation in the perception regarding misstatement and responsibility in the presentation of financial statements. Moreover, there is differentiation in the perception of complying with Law No. 18 of 2019 concerning Islamic Boarding Schools (Ponpes). Additionally, there is differentiation in the understanding of the PSAK Accounting Standards for Islamic Boarding Schools among the caretakers, accounting students, and non-accounting students.
TECNOLOGIA, BNCC E ENSINO MÉDIO: O USO DE FERRAMENTAS TECNOLÓGICAS NO ENSINO DE LITERATURA
Authors: Silva Lucas Almeida
Published: May 2024

A presente pesquisa teve por objetivo identificar em que medida o uso de mídias digitais pode auxiliar o processo de ensino-aprendizagem de alunos do Ensino Médio na disciplina de Literatura. Tal estudo justifica-se pelo fator intrínseco que a Literatura e a Tecnologia apresentam ao desenvolvimento de competências e habilidades voltadas ao campo Linguagens, Códigos e suas Tecnologias, previstas na BNCC (2018). Como metodologia, foram aplicadas ferramentas quali-quantitativas: 1) questionário voltado a professores que atuam na disciplina de Literatura, no Ensino Médio, e 2) entrevista com um grupo de alunos da 1ª série do Ensino Médio na Sphere International School, em São José dos Campos, São Paulo, a respeito da importância do uso de Tecnologias no estudo de Literatura. Como resultado, pôde-se observar que professores e alunos consideram o uso de diferentes tecnologias como parte essencial de atividades mais significativas e dinâmicas no contexto do ensino de Literatura.
ARTRITE REUMATOIDE EM VÍDEOS PERCEPÇÃO DE ESTUDANTES DE SAÚDE ANTES E APÓS A EXIBIÇÃO DE VÍDEOS SOBRE A DOENÇA
Authors: Neco Heytor Victor Pereira da Costa , Barreto Sandra Patrícia Ferreira , Santana Monally Alves de
Published: May 2024

A artrite reumatoide é uma doença de etiologia desconhecida, afetando cerca de 1 a 2% da população, principalmente mulheres e tem como característica principal o processo inflamatório. Esse processo acomete as articulações, podendo resultar em danos permanentes e incapacitantes. Os pacientes com artrite reumatoide (AR) precisam ser monitorados, portanto devem contar com profissionais bem capacitados, sendo assim, é de grande relevância que graduandos dos cursos de saúde detenham conhecimento a cerca dessa enfermidade e como realizar seu correto manejo. Diante disso, essa pesquisa teve como objetivo avaliar o conhecimento dos estudantes dos cursos de saúde de um centro universitário em Recife – PE sobre a importância da nutrição aplicada ao manejo da artrite reumatoide. Tratou-se de uma pesquisa descritiva, com abordagem quantitativa e qualitativa, de caráter transversal, por meio do levantamento de dados de uma amostra composta por noventa (90) estudantes dos cursos de saúde. A coleta de dados foi realizada de forma presencial por meio de aplicação de dois formulários: pré-exibição de três vídeos curtos e pós-exibição dos vídeos. Após análise dos dados, observou-se que a maioria dos estudantes (60%) não detinham conhecimento a respeito do diagnóstico da artrite reumatoide e 68,89% dos estudantes desconheciam seu manejo, aspecto de grande relevância no curso dessa doença e seu prognóstico. Os resultados desse projeto possibilitaram sensibilizar os estudantes a respeito da importância da nutrição aplicada ao manejo da artrite reumatoide, por meio da apresentação dos vídeos, aumentando o conhecimento dos estudantes, ajudando na prevenção da doença e atuando como propagadores do conhecimento.
A IMPORTÂNCIA DA BRINCADEIRA E O PAPEL DAS NOVAS TECNOLOGIAS DIGITAIS PARA A APRENDIZAGEM INFANTIL
Authors: Câmara Tânia Cecília , Arantes Sheila da Silva Ferreira , Legey Ana Paula
Published: May 2024

O brincar é um ato humano que permite a vivência de situações lúdicas que ajudam no desenvolvimento de suas potencialidades criativas e imaginativas. Observa-se que as formas de brincar foram se transformando com o passar do tempo e as brincadeiras na atualidade estão associadas com o uso da tecnologia. O objetivo do presente artigo é mostrar a importância da brincadeira para a aprendizagem infantil e como o surgimento das novas tecnologias mudaram o brincar na atualidade. A metodologia utilizada foi a revisão de literatura com a consulta à livros, artigos, documentos e normas encontrados em bases de dados e bibliotecas digitais. O material selecionado contou com a inclusão de artigos em português, publicados entre 2018 e 2023, em revistas e periódicos da área da educação. A análise de conteúdo mostrou os subtemas principais para a compreensão do tema, que foram: o brincar aliado ao uso das novas tecnologias digitais; o desafio para ensinar as novas gerações e a necessidade da formação docente para tal cenário. A abordagem ofereceu a compreensão das mudanças ocorridas na sociedade impulsionadas pelos avanços tecnológicos, o que demanda a preocupação das escolas com propostas de práticas educativas que possam contribuir de forma positiva para o desenvolvimento infantil. Conclui-se que o uso das novas tecnologias podem tornar as aulas divertidas, prazerosas e significativas.
Post-traumatic stress disorder and how it affects memory
Authors: Melo Ágda Rayane Gomes de Moura , Olegário Aísha Laryssa Nascimento , Santos Géssica Manuelle Ferreira dos , Silva Girleide Estevam Lopes da , Conceição Inajara Marques de , Medeiros Jamile Quésia Félix de , Santos Maria Eduarda do Nascimento , Oliveira Maria Juliana de , Oliveira Rayssa Jenefer Silva de , Nascimento Richerlaine Gregório da Silva , Rodrigues Thamires Soares da Silva , Felix Pierre Teodosio
Published: May 2024

Post-traumatic stress disorder (PTSD) generates different debates about its impacts on memory. Stress is linked to the production of cortisol, which has the function of keeping our body in "alert", thus generating fight or flight behaviors, but with human evolution, these innate survival behaviors have been poorly adapted to the present day, thus causing in the long term the development of mental disorders such as PTSD causing memory impairment. The objective of this article was to convey the damage caused by PTSD in memory, the discussions regarding contemporary interpretations of trauma, the evolution of the understanding of trauma over time, in addition to pointing out the differences between Brazilian and foreign articles. In order to develop this study, a literature review was used to address the aforementioned themes.
Effects of early mobilization in critically ill patients in intensive care units: an integrative review of the literature
Authors: Souza Carolina Beatriz de Oliveira , Silva Junio de Lira , Santos Lucas José dos , Silva Alisson Gil Dias , França Rubens Guilherme Pereira de , Santos Filho José Luís dos , Silva Luan Renato Santana da , Melo Palloma Emanuelle Dornelas de , Monteiro Bruna Rafaela Dornellas de Andrade Lima
Published: May 2024

Introduction: Mechanical ventilation is a procedure essentially used in intensive care units (ICUs) to provide respiratory support to patients with acute respiratory failure. Although it is a vital intervention, prolonged mechanical ventilation time can lead to significant complications, such as muscle weakness, atrophy, respiratory dysfunction, and increased length of ICU stay. Methodology: Data collection took place through the Coordination for the Improvement of Higher Education Personnel (CAPES), Google Scholar, Scielo, PubMed and BIREME, through bibliographic research of articles published in the period from 2017 to 2022. Findings: The sample consisted of 133 articles, of which 122 were pre-selected, 86 excluded, totaling 05 articles for the final sample. Final Thoughts: Through this study, it was possible to conclude that ICU-acquired muscle weakness is a frequent complication that can happen to several patients admitted to the Intensive Care Unit , which can impair the area of muscle mass and strength, causing various problems related to prolonged hospitalization time, mechanical ventilation and neuromuscular blockers.
O USO DE JOGOS ONLINE NO ENSINO DE CIÊNCIAS
Authors: Santana Dayana Aléxia Oliveira , Oliveira Sérgio Renato , Almeida Karina Carvalho de , Costa Franciellen Morais
Published: May 2024

RESUMO
Os jogos virtuais são criados com suas regras, com cores chamativas, músicas e acompanhando as visões
de mercado, tudo para chamar atenção do público alvo em que será utilizado, despertando fascínio e desejo, assim como, é uma opção dos docentes chamarem a atenção dos estudantes e explicar os conteúdos de uma maneira mais lúdica. É válido pensar que os jogos podem auxiliar alunos com TDAH (Transtorno do Déficit de Atenção com Hiperatividade). Objetivou-se realizar uma revisão sistemática de artigos com o intuito de analisar como os jogos são aceitos em sala de aula, de forma positiva ou negativa, e como estes os jogos podem contribuir no ensino. Essa pesquisa abrangeu quatro bases de dados: Google Acadêmico, SciELO, Scorpus e Web of Science. Os artigos analisados para o desenvolvimento do trabalho foram estabelecidos no período de 2018 a 2023. É possível afirmar que a maioria dos alunos tem resultados po?sitivos nas provas quando utilizam os jogos online como ferramenta educativa e de fixação das matérias, o que proporciona um ensino mais qualitativo e proveitoso.
Palavras-chave: Ludicidade, Tecnologias Digitais, Recursos Digitais.
EDUCAÇÃO CONTEMPORÂNEA: DESAFIOS E PERSPECTIVAS
Authors: Silva Ângela Cristina Rodrigues da , Costa Rozalina Cássia de Andrade Ruas , Cardoso Filho Otávio
Published: May 2024

RESUMO
A educação contemporânea enfrenta uma série de desafios que demandam uma reflexão crítica por parte dos educadores. Neste contexto, a partir de uma revisão de literatura, este texto tem como objetivo discutir questões chave enfrentadas pelos educadores no contexto atual. Destacam-se a necessidade premente de desenvolver habilidades do século XXI entre os alunos, a importância da promoção da inclusão e di?versidade, e a adaptação aos novos modelos de aprendizagem. Através de uma análise de diversos estudos e abordagens, busca-se fornecer insights e orientações para os educadores enfrentarem esses desafios de
forma eficaz e construtiva, promovendo uma educação mais relevante e inclusiva para todos os alunos.
Palavras-chave: Produção do conhecimento. Ensino aprendizagem. Políticas públicas.
6 Histórias para descobrir
Authors: Tavares Vanessa dos Santos , Barreto Jessé
Published: May 2024

Este eBook foi produzido por pessoas que sonham com uma educação transformadora e justa para
as muitas infâncias, com a colaboração de mães, pais, professoras/es, nutricionistas e psicólogas/os.

Nosso público-alvo são crianças da Educação Infantil e dos anos iniciais do Ensino Fun-
damental e, por meio da ludicidade contida na literatura infantil, nas histórias e nas ima-
gens, tratamos das temáticas como amizade, cooperação, diversidade, educação alimen-
tar, educação especial inclusiva, imaginação, respeito, superação de medos e tolerância.

As narrativas tecem histórias contadas às crianças por adultos que trazem emoções, ênfa-
ses, entonações, medos, risadas, sustos, além do mundo fantástico que conformam com o conte-
údo da narrativa. As histórias ilustram representações de mundo que povoa o imaginário infantil.

Este livro apresenta 6 histórias que possibilitam aventuras incríveis. Te convidamos a viajar por essas
belas e maravilhosas narrativas!!! Vamos viajar pelas leituras???

Professor Jessé Barreto
ANÁLISE DO POTENCIAL DE CANTINAS E RESTAURANTES DE ESCOLAS PARTICULARES DO PLANO PILOTO EM BRASÍLIA COMO CIRCUITO CURTO DE COMERCIALIZAÇÃO DE PRODUTOS DA AGRICULTURA FAMILIAR
Authors: Bie Aloisio Alves , Nogueira Solange da Costa
Published: May 2024

Os padrões de consumo de alimentos foram drasticamente alterados nas últimas décadas, com o predomínio de alimentos processados, produzidos em complexos agroindustriais longe dos locais de consumo. Este distanciamento dos centros de produção e consumo requer uma logística sofisticada para vencer grandes distâncias em tempos exíguos. É o que a literatura especializada denomina de circuitos longos de comercialização, fundados sobretudo no modelo agroalimentar industrial. Excluídos desse ambiente impessoal, altamente exigente em grande escala de produção, os agricultores familiares começam a
buscar uma ligação direta entre produtor e o consumidor, emergindo o conceito de circuitos curtos de comercialização. Nessa perspectiva, podem ganhar visibilidade ambientes de comercialização antes inexplorados pelos agricultores familiares, como é o
caso dos estabelecimentos alimentares da rede particular de ensino, que podem se tornar grandes aliados na promoção da alimentação saudável de crianças e adolescentes. Este trabalho apresenta um resumo expandido de pesquisa realizada em estabelecimentos de
ensino particulares no Plano Piloto de Brasília, DF, avaliando o potencial destes como
mercado para produtos hortifrútis da agricultura familiar
EFFECT OF NITRO COMPOUNDS ON in vitro RUMINAL METHANE, CARBON DIOXIDE, HYDROGEN AND DRY MATTER DEGRADABILITY
Authors: Ochoa-García Pedro Antonio , Anderson Robin C. , Rodríguez-Almeida Felipe Alonso , Maynez-Pérez Adrián Omar , Felix-Portillo Monserrath , Muro-Reyes Alberto , Bozić Aleksandar K. , Arevalos-Sánchez Martha María , Vargas-Bello-Pérez Einar , Corral-Luna Agustín
Published: May 2024

This study determined the in vitro effects of ethyl nitroacetate (ENA), ethyl 2-nitropropionate (E-2-NPP) and 3-nitropropionic acid (NPA) on ruminal production of CH4, H2, volatile fatty acids (VFAs) and in vitro dry matter disappearance of ground alfalfa. In vitro incubations were carried out over 24-h succeeding days (3 batches). Total gas and methane production decreased with all nitro compounds (P 0.05) in all the batches. Total production of VFAs was reduced by ENA and E-2-NPP (P 0.05), but not by NPA. DM disappearance was similar between treatments but decreased across batches. Further studies should be aimed at understanding the impact of NPA on ruminal metabolism, as well as its effect on in vivo models.
Formulation of colloidal astringent solution using green tea and neem oil
Authors: Samata Biswas  , N. N. Bala  , Sanjiban Utpal Sarkar  , Madhurina Dutta
Published: May 2024

This thesis explores the formulation of a novel colloidal astringent solution utilizing the synergistic properties of green tea and neem oil in skincare applications. Astringents play a crucial role in skincare, offering benefits such as pore tightening, oil control, and skin texture refinement. Green tea and neem oil, renowned for their antioxidant, anti-inflammatory, and antimicrobial properties, present promising ingredients for enhancing skin health. The study begins with a comprehensive literature review, examining previous research on astringents, green tea, and neem oil. This review elucidates the individual properties and skincare benefits of these ingredients, providing a foundation for their integration into a colloidal solution. Relevant formulation techniques for colloidal solutions and astringents are also reviewed, informing the experimental approach. Experimental design focuses on formulating a colloidal astringent solution using green tea extract and neem oil, with the aim of harnessing their collective potency. Physicochemical properties of the solution, including pH, viscosity, particle size, and stability, are characterized to evaluate its suitability for skincare applications. Stability studies over time provide insights into the shelf-life and efficacy of the formulation. Results demonstrate the successful formulation of a colloidal astringent solution with optimized properties, showcasing the potential synergy between green tea and neem oil. Analysis of experimental findings highlights the formulation's efficacy in addressing common skincare concerns, such as pore refinement, oil control, and inflammation reduction. The study contributes to the growing body of knowledge in natural skincare formulations, offering insights into the development of innovative products that marry tradition with modern science. In conclusion, the formulation of a colloidal astringent solution using green tea and neem oil represents a promising approach to skincare, leveraging the therapeutic benefits of natural ingredients. Future research may explore clinical applications and further optimization of the formulation to maximize its efficacy and safety in diverse skincare routines.
Formulation and evaluation of Dorzolamide hydrochloride microsponges loaded in situ gel for ocular administration
Authors: Grace Rathnam  , G. Sangeetha
Published: May 2024

Due to the unique structure of the eye, which inhibits the entry of drug molecules into the desired site, the ophthalmic delivery of the drug has been one of the most challenging tasks for a pharmaceutical scientist. For this reason, in this investigation a novel microsponge for an anti-glaucoma drug, Dorzolamide hydrochloride, was formulated as in situ gel for ocular administration with an aim to improve its therapeutic efficacy and reduce the systemic adverse effects. The microsponges were prepared by the quasi emulsion solvent diffusion method and was incorporated into 20% pluronic F-127 which led to consistent in situ gel at 35°C. They were evaluated for physicochemical properties like pH, gelling capacity, gelation time, rheological properties and release profile and ocular irritancy test. The prepared Dorzolamide hydrochloride microsponges showed high entrapment efficiency of 85% and mean particle size of 2 μm with polydispersity index (PDI) of 0.77 which are ideal for ocular delivery. These microsponges is formulated into in situ gel which showed higher therapeutic efficacy compared to free drug in gel. It was found to be non-irritant to the rabbit’s eye. These results confirms that Dorzolamide hydrochloride microsponges in situ gels have promising features, benefits and advantages for a novel ophthalmic drug delivery to treat glaucoma.
GARLIC: Nature's potent antifungal and antibacterial ally - cream formulation and evaluation
Authors: Pranali Kunteshwar Rabade  , Rajesh Z. Mujariya  , Manjeet Singh
Published: May 2024

In the pursuit of effective and safe treatments for infectious diseases, herbal remedies have garnered significant attention due to their diverse phytochemical composition and potential therapeutic properties. This study aimed to explore the phytochemical profile and evaluate the antibacterial and antifungal properties of herbal garlic extracts. Traditional natural products continue to be sought after for their bioactive compounds, which offer promising avenues for therapeutic intervention in both human and veterinary medicine. Our investigation not only sheds light on the regional variation of stomach disease occurrence, highlighting the role of dietary factors, but also underscores the importance of herbal preparations in medicinal practice. By combining various plant classes, herbal formulations can exert localized effects upon application, penetrating the skin or mucous membranes to target underlying conditions. The effectiveness of these combined medications may lie in their synergistic mechanisms, offering a comprehensive therapeutic approach. This research contributes valuable insights into the potential of herbal remedies as adjuncts or alternatives to conventional treatments, paving the way for further exploration in infectious disease management and prevention strategies.
Generativität und Identität
Authors: Preuss Wilhelm F.
Published: May 2024

Ausgehend von gesellschaftlichen Veränderungen, die zur geschlechtlichen Diversität vor allem bei Jugendlichen beigetragen haben könnten, beschäftige ich mich rückschauend damit, wie sich meine Sichtweisen und Einstellungen als Sexualund Trans*Gender-Therapeut in den vergangenen 30 Jahren verändert haben. Dazu betrachte ich den Wandel der Geschlechterordnung vor dem Hintergrund rasanter gesellschaftlicher und globaler Veränderungen einerseits und intrapsychische Aspekte der psychosexuellen Identitätsbildung andererseits. Ich orientiere ich mich am Konzept der konstitutionellen Bisexualität und an E. H. Eriksons Entwicklungstheorie.
Climate change research, capacity building and communication on climate extremes over South Asia
Authors: Ali Shaukat , Reboita Michelle Simões , Kiani Rida S. , Goheer Muhammad Arif , Saeed Alia , Muhammad Sher , Khan Firdos , Rahman Md Mizanur , Shreshta Madan L. , Dan Li , A Bhutta Zulfiqar
Published: May 2024

Climate change is a global issue that significantly impacts various regions, including South Asia, which is particularly vulnerable to climate extremes. Extensive research is required to address the complex interplay between climate change and extreme weather events in South Asia (Bangladesh, Nepal and Pakistan). This study presents a case study of an Asia-Pacific Network for Global Change Research (APN) project focusing on climate change research, capacity buildingand science-to-policy communication on climate extremes in South Asia. Climate change research emphasises the importance of research to understand the changing patterns and impacts of climate extremes in the region. It underscores the need for robust scientific methodologies, data collectionand analysis to generate reliable evidence for policymakers and stakeholders. The capacity building efforts involve training programmes, workshopsand knowledge-sharing platforms, which are critical to enhancing the capabilities of local researchers, institutionsand communities in conducting climate change research and developing adaptation and mitigation strategies. The science communication includes disseminating the study’s findings to stakeholders, including policymakers, researchers, communities, mediaand civil society organisations. Overall, collaborative efforts between South Asian countries are important for climate change research, capacity buildingand science-to-policy communication to build resilience and mitigate the impacts of climate change.
Identification and genotyping of Chikungunya virus using reverse transcription polymerase chain reaction and restriction fragment length polymorphism methods
Authors: Netesova N. A. , Abdurashitov M. A. , Samartseva T. G. , Klimovich O. V. , Oksanich A. S. , Otrashevskaia Е. V. , Ignatyev G. M.
Published: May 2024

INTRODUCTION. Chikungunya virus (CHIKV) genotyping involves sequencing fractions of genes encoding E1, E2, and nsP1 proteins or the entire genome of the virus. Available reagent kits or polymerase chain reaction protocols cannot be used for CHIKV genotyping, and nucleic acid sequencing requires expensive equipment and materials, which are not always available. Therefore, it seems promising to use a simpler and more cost-effective restriction fragment length polymorphism (RFLP) method, which has not previously been used for CHIKV genotyping.

AIM. This study aimed to investigate the possibility of using reverse transcription polymerase chain reaction (RT-PCR) and RFLP for CHIKV identification and genotyping.

MATERIALS AND METHODS. The experimental study used RNA from CHIKV strains of four genotypes, including the Asian, West African (WAf), and East/Central/South African (ECSA) genotypes, and the Indian Ocean Lineage of the ECSA genotype (ECSA-IOL). The study used RT-PCR followed by DNA restriction and restriction fragment length analysis.

RESULTS. The nsP2 gene fragment of 648 bp in length (positions 3806 to 4453) contains recognition sites for the restriction endonucleases PspEI, PvuII, and DraI. The presence or absence of these sites generates a different combination specific to each of the four CHIKV genotypes. The authors designed primers for amplification of the selected gene region and performed RTPCR and RFLP.

CONCLUSIONS. The RFLP method can be used for rapid CHIKV identification and genotyping. The method provides results within a few hours and does not require high-tech equipment.
Использование витаминно-минерального препарата in ovo для стимуляции эмбрионального развития, метаболизма, вывода и здоровья молодняка кур яичного направления продуктивности
Authors: Корчемкин Владимир Николаевич , Сулейманов Фархат Исмаилович , Челноков Андрей Алексеевич , Челнокова Марина Игоревна
Published: May 2024

Изучено влияние 0,1 % раствора «Бутофан» in ovo, который вводили на 7-е сутки инкубации через отверстие скорлупы в воздушную камеру яйца для стимуляции эмбрионального развития, метаболизма, вывода и здоровья молодняка кур кросса «Ломанн Браун». Применение витаминно-минерального препарата «Бутофан» in ovo стимулировал рост массы у 20-суточных куриных эмбрионов: тела — на 2,81 г, печени — на 0,209 г, сердца — на 0,048 г, мышечного желудка — на 0,375 г, селезёнки — на 0,007 г, правой доли тимуса — на 0,007 г; повышал уровень метаболизма по выделению углекислоты и поглощению кислорода — соответственно на 2,21 и 1,56 мл/ч по сравнению с контролем (без инъекций). Установлено превосходство препарата «Бутофан» по количеству выведенных цыплят по отношению к контролю, который был достоверно выше на 4,82 %, выводимости яиц — на 4,59 %. Последействие раствора «Бутофан» во время инкубации повышает массу тела суточных цыплят в 1,06 раза и ускоряет обменные процессы на 0,46 ккал/сут., способствует улучшению качества суточного молодняка по шкале «Пасгар», которое превышало на 0,94 балла, что указывает на его высокую результативность использования и длительность эффекта последействия.
Биотипный состав сортов и селекционных линий голозерного овса немчиновской селекции
Authors: Кабашов Александр Дмитриевич , Любимова Анна Валерьевна , Колупаева Анастасия Сергеевна , Власенко Николай Михайлович , Михалин Станислав Евгеньевич , Лейбович Яков Григорьевич , Разумовская Любовь Григорьевна , Филоненко Зинаида Владимировна , Лапаткина Ольга Владимировна
Published: May 2024

Голозерные овсы малоурожайны и мелкосемянны. Селекцию осложняет нестабильность по полноте вышелушивания зерна. Наиболее эффективное направление в селекции голозерного овса — скрещивание с овсом пленчатым. В конкурсном сортоиспытании к 2022 г. изучали биотипный состав 2 сортов и 12 селекционных линий голозерного овса. Элитные растения, полученные в результате скрещиваний, отбирали из 4-го поколения, когда расщепление начинает затухать. Установлена гетерогенность подопытного материала по компонентному составу авенина. Разработаны эталонные спектры проламина представленных сортообразцов. Указаны основные причины и источники засорения, сопутствующие селекционному процессу. Предложено контролировать биотипный состав сортов голозерного овса методом электрофореза.
Продуктивность зимних сортов яблони в интенсивных насаждениях на слаборослом подвое М9
Authors: Хамурзаев Салман Магомедович , Лабазанов Исрапил Израилович
Published: May 2024

Современные требования интенсификации садоводства предполагают усиление работы по созданию и внедрению в производство новых высокопродуктивных сортов плодовых культур (в частности яблони), отвечающих требованиям интенсивных технологий и устойчивых к неблагоприятным воздействиям внешней среды. Решение этой проблемы возможно при интенсификации садоводства, т.е. при применении уплотненных посадок плодовых деревьев; создании и внедрении сортов интенсивного типа: скороплодных, высокоурожайных, с малогабаритными кронами, иммунных и высокоустойчивых, зимостойких, частично и полностью самоплодных с продолжительной лежкостью и хорошими вкусовыми качествами плодов. Опыт по изучению влияния плотности посадки на рост и урожайность яблони был заложен в 2012 г. в Чеченской Республике. Представлены результаты многолетних исследований (2017 – 2022 гг.) и анализ закономерностей роста и развития деревьев яблони в зависимости от схемы размещения. Особенности роста и развития зимних сортов яблони изучали при различных схемах посадки в суперинтенсивном саду.
Peningkatan Karakter Disiplin Anak Usia 5-6 Tahun melalui Media Audio Visual
Authors: Ima Nur Asrima , Sitorus Ahmad Syukri
Published: May 2024

Mengkaji kemampuan pengaturan diri anak sejak dini sangatlah penting karena hal ini menjadi landasan fundamental bagi pencapaian masa depan. Penelitian ini dilatar belakangi oleh rendahnya kedisiplinan pada anak yang seharusnya hal ini harus ditingkatkan sejak anak usia dini dengan mengunakan media audio visual sebagai media pendukung dalam meningkatkan kedisiplinan anak tersebut. Penelitian ini menggunakan metodologi penelitian tindakan kelas. Penelitian ini terutama berfokus pada kelas B yang terdiri dari anak-anak berusia 5 sampai 6 tahun. Tujuan penelitian ini adalah untuk meningkatkan tingkat kedisiplinan anak usia 5-6 tahun melalui pemanfaatan media audiovisual. Penelitian ini mengambil sampel sebanyak 23 anak, terdiri dari 11 laki-laki dan 12 perempuan. Penelitian dilakukan dalam dua siklus penelitian. Perlakuan yang diberikan untuk siklus I dan siklus II perbedaannya pada pembiasaan dan penguatan. Hasil penelitian menunjukkan bahwa pemanfaatan media audio mempunyai pengaruh yang cukup besar terhadap peningkatan kedisiplinan anak.
Pengembangan Kemampuan Membaca Anak Usia 5-6 Tahun Menggunakan Metode Drill
Authors: Nafisa Rahma Sayyida , Fitriani Yulianti , Nuroniah Pepi
Published: May 2024

Penelitian ini didasarkan pada hasil pengamatan terhadap kondisi pembelajaran yang memperlihatkan adanya kesulitan yang dialami anak untuk membedakan bentuk-bentuk huruf A-Z. Tujuan dari penelitian ini adalah untuk mengembangkan kemampuan membaca anak menggunakan metode drill. Metode drill dilakukan secara berulang dan sesuai digunakan untuk anak. Penelitian ini menggunakan metode deskriptif kualitatif dengan pengumpulan data diambil melalui observasi, wawancara dan diperkuat dengan dokumentasi yang dilakukan kepada pendidik dan 15 anak kelompok usia 5-6 tahun. Teknik analisis data yang digunakan reduksi data, penyajian data dan verifikasi data. Hasil penelitian berupa peningkatan kemampuan membaca anak yang ditunjukkan dengan tingginya tiga diantara sepuluh indikator penelitian yang dikembangkan yakni pertama anak dapat menyebutkan dan membedakan bentuk lambang huruf A-Z, kedua anak dapat mengucapkan huruf vokal a i u e o tanpa pengulangan, dan ketiga minat membaca anak semakin meningkat. Penelitian ini dapat direkomendasikan sebagai alternatif upaya untuk membantu proses pengembangan kemampuan anak menggunakan metode drill khususnya membaca ataupun kemampuan lainnya.
Delineating neighbourhoods: An urban morphology and multi-dimensional approach
Authors: Govind Anirudh , Poorthuis Ate , Derudder Ben
Published: May 2024

Although neighborhoods are a widely used analytical concept in urban geography, in empirical research, they are often proxied using grids or statistical sectors. The rationales underlying these proxies are often separated from the theoretical considerations of what makes a neighborhood a neighborhood, casting shadows over their relevance and applicability. In this paper, we identify two specific challenges separating empirical operationalizations from theoretical considerations in neighborhood delineations: (1) not incorporating key built environment elements and (2) monodimensional approaches. We address these issues by developing a method that addresses this double challenge by (1) creating morphological basic spatial units (BSUs) and (2) aggregating them using multilayer community detection. We illustrate this method for the case of Leuven, Belgium, by (1) using street blocks as BSUs and (2) focusing on proximity, land use, and daily activity pattern interactions. Ground-truthing these neighborhoods and contrasting results with those derived from grids and statistical sectors, we show that this approach has the ability to better approach the structure of the city. We therefore argue that our approach offers clear advantages over currently used approximations through its flexibility, inherent explanatory power and alignment with theoretical considerations, making a strong case for its adoption in neighborhood delineation exercises.
Imipramine: the influence of its metabolite plasma levels on treatment response?
Authors: Kasanmonadi Roan Yannick Noah , Kamperman Astrid Mariska , Koch B.C.P. , Birkenhager T.K.
Published: May 2024

BackgroundIn therapeutic drug monitoring (TDM) of imipramine treatment, combined plasma levels of imipramine and its metabolite desipramine are usually assessed, often without paying attention to individual plasma levels. Imipramine and desipramine differ in their pharmacokinetic properties. Previous research suggested that high desipramine levels might negatively influence imipramine treatment efficacy in generalized anxiety disorder. We aimed to explore the relationship between separate imipramine and desipramine levels and treatment response in depressed inpatients.MethodsWe conducted a retrospective study involving inpatients with major depression disorder who underwent five-week imipramine treatment. Weekly sum levels were measured with subsequent dose adjustments until reaching adequate levels. We assessed response rates on the 17-item Hamilton Rating Scale for Depression (HDRS17) and compared imipramine and desipramine plasma levels between responders and non-responders using Mann-Whitney U tests.Results/OutcomesAfter five weeks of treatment, non-responders exhibited significantly higher desipramine levels (P = 0.015) and combined plasma levels (P = 0.020) compared to responders. Imipramine levels did not significantly differ between groups. Additionally, higher desipramine levels corresponded to smaller changes on the HDRS17, whereas higher imipramine plasma levels corresponded to greater changes. Plasma levels did not significantly differ between patients with and without concomitant CYP2D6 or CYP2C19 inhibiting medication.Conclusion/InterpretationOur findings suggest that desipramine plasma levels were higher in non-responders to imipramine treatment, implying a potential negative impact on imipramine’s therapeutic effect. In the future, it may prove important to consider metabolite plasma levels alongside combined plasma levels when performing TDM.Declaration of interest/FundingThe authors declare no conflicts of interest and received no specific funding for this research.
What neuroimaging methods can tell us about perceptual development
Authors: Aslin Richard , Bejjanki Vikranth R
Published: May 2024

Over the past several decades, behavioral methods suitable for use with human infants have revealed detailed characteristics of perceptual development, but the causal mechanisms that drive these behavioral changes remain elusive. Neuroimaging methods hold the promise of clarifying these causal mechanisms by reducing the hypothesis space of theories for how biological and experiential factors interact as perceptual abilities emerge and become refined during early development. Here we review behavioral milestones in several key areas of perceptual development in infancy and childhood, summarize the potential value-added of neural measures, and highlight the promise of new analytic techniques that can further clarify these causal mechanisms in the future. We also outline patterns of interaction during development that describe how neural and behavioral findings change with age and raise some cautionary notes about how to interpret these interactions.
Ambiguity Detection in Mental Models: Evidence from naturalistic Texts
Authors: Laursen Calvin Christopher , Wiener Jan , Vasilev Martin R. , Slattery Timothy J.
Published: May 2024

Previous research on mental models (e.g., Goodwin & Johnson-Laird, 2005; Rips, 1994; Johnson-Laird, 2001; Rauh et al., 2005) has focused on which, how and why mental models are created by readers, however it is not clear whether people notice if/when there is more than one interpretation (ambiguity), without being prompted. We present a novel naturalistic reading methodology for studying readers’ ability to “detect” if an object/subject order was ambiguous or not. This paper presents a methodology for investigating ambiguity “detection” that uses premises similar to mental models research (e.g., Goodwin & Johnson-Laird, 2005; Nejasmic, Bucher & Knauff, 2015) which were embedded into paragraphs. Our findings are consistent with prior research (e.g., Johnson-Laird, 1994), as we found that participants often fail to detect ambiguity, if the premises are consistent with two viable models. We found that older participants (60+) perform no better or worse compared to younger participants in detecting ambiguity or in their ability to make inferences from mental models. However, consistent with prior research, we found that older participants took significantly longer both to read and to answer. Through the use of paragraph stimuli, this paper replicates prior findings of people’s “blindness” to alternative models and that, although slower, older readers do not differ from younger readers in their ability to construct and make inferences from mental models.
Event segmentation promotes the reorganization of emotional memory
Authors: Laing Patrick , Dunsmoor Joseph E.
Published: May 2024

Event boundaries help structure the content of episodic memories by segmenting continuous experiences into discrete events. Event boundaries may also serve to preserve meaningful information within an event, thereby actively separating important memories from interfering representations imposed by past and future events. Here, we tested the hypothesis that event boundaries organize emotional memory based on changing dynamics as events unfold. We developed a novel threat-reversal learning task whereby participants encoded trial-unique exemplars from two semantic categories across three phases: preconditioning, fear-acquisition, and reversal. Shock contingencies were established for one category during acquisition (CS+) then switched to the other during reversal (CS-). Importantly, reversal was either separated by a perceptible event boundary (experiment 1) or occurred immediately after acquisition, with no perceptible context shift (experiment 2). In a surprise recognition memory test the next day, memory performance tracked the learning contingences from encoding in experiment 1, such that participants selectively recognized more threat-associated CS+ exemplars from before (retroactive) and during acquisition, but this pattern reversed toward CS- exemplars encoded during reversal. By contrast, participants with continuous encoding—without a boundary between conditioning and reversal—exhibited undifferentiated memory for exemplars from both categories encoded before acquisition and following reversal. Further analyses highlight nuanced effects of event boundaries on reversing conditioned fear, updating mnemonic generalization, and emotional biasing of temporal source memory. These findings suggest that event boundaries provide anchor points to organize memory for distinctly meaningful information, thereby adaptively structuring memory based on the content of our experiences.
The ReSearching Identity Podcast Project: Developing a Brief and Inclusive Professional Identity Intervention for Higher Education
Authors: Vietze Jana , Meeuwisse Marieke , de Haan Amaranta , Wolff Rick , de Koning Bjorn
Published: May 2024

In this study, we present the pilot implementation of the ReSearching Identity Podcast Project, an intervention targeting the professional identity development of students with and without marginalized identities in higher education. The objectives were to assess the intervention's acceptability and feasibility, particularly focusing on its use of educational podcasting, and to explore preliminary effects on students' professional identity, including identity centrality and the connectedness with social identities (i.e., cultural and gender identity). We conducted a mixed method pilot study with university students (N=33; 88% female) in the Netherlands. Students completed online surveys before and after the pilot implementation, and students and their teacher participated in follow-up conversations. The results supported the acceptability and feasibility of the ReSearching Identity Podcast Project, with students and teachers appreciating the brevity of the intervention program, opportunities to learn about marginalized experiences of fellow students and professionals, and embeddedness in the curriculum. Also, students reported higher professional identity centrality and overall high connectedness of professional and other social identities after the intervention. We conclude by addressing the limitations, but also potential of the ReSearching Identity Podcast Project to address professional identity development with all students in higher education.
Disability discrimination in hiring: A systematic review
Authors: Schwitter Nicole , Chatzitheochari Stella , Liebe Ulf
Published: May 2024

Despite well-documented disability gaps globally, there is a lack of research using experimental methods to study discrimination in recruitment, which may constitute a major pathway through which the disability employment gap is sustained. In this paper, we review existing evidence on experimental research on disability discrimination in hiring and outline key areas for future research in the field. Our review underlines significant differences in callback rates based on disability status, and variability in effect sizes across different conditions/impairments. We also find that certain conditions/impairments have received more empirical attention than others. Exploring discrimination levels across a wider range of conditions and impairments is necessary to move beyond monolithic understandings of disability as a binary ascriptive status and to discern different causal mechanisms associated with adverse employment outcomes among different impairment/condition groups. We argue that intersectional, theoretically grounded, and cross-national experimental approaches are needed to better understand discrimination in hiring.