bluuebunny/crossref_metadata_2025 huggingface dataset:
Absorption-Enhanced Ultra-Thin Solar Cells Based on Horizontally Aligned p–i–n Nanowire Arrays
Authors: Yuan Xueguang , Chen Xiaoyu , Yan Xin , Wei Wei , Zhang Yangan , Zhang Xia
Published: June 2020

A horizontally aligned GaAs p–i–n nanowire array solar cell is proposed and studied via coupled three-dimensional optoelectronic simulations. Benefiting from light-concentrating and light-trapping properties, the horizontal nanowire array yields a remarkable efficiency of 10.8% with a radius of 90 nm and a period of 5 radius, more than twice that of its thin-film counterpart with the same thickness. To further enhance the absorption, the nanowire array is placed on a low-refractive-index MgF2 substrate and capsulated in SiO2, which enables multiple reflection and reabsorption of light due to the refractive index difference between air/SiO2 and SiO2/MgF2. The absorption-enhancement structure increases the absorption over a broad wavelength range, resulting in a maximum conversion efficiency of 18%, 3.7 times higher than that of the thin-film counterpart, which is 3 times larger in GaAs material volume. This work may pave the way for the development of ultra-thin high-efficiency solar cells with very low material cost.
Systems Nutrology of Adolescents with Divergence between Measured and Perceived Weight Uncovers a Distinctive Profile Defined by Inverse Relationships of Food Consumption
Authors: Andrade Vanessa M. B. , Santana Mônica L. P. de , Fukutani Kiyoshi F. , Queiroz Artur T. L. , Arriaga Maria B. , Damascena Nadjane F. , Menezes Rodrigo C. , Fernandes Catarina D. , Conceição-Machado Maria Ester P. , Silva Rita de Cássia R. , Andrade Bruno B.
Published: June 2020

Changes in food consumption, physical inactivity, and other lifestyle habits are potential causes of the obesity epidemic. Paradoxically, the media promotes idealization of a leaner body appearance. Under these circumstances, self-perception of weight by adolescents may be affected. Here, we performed a cross-sectional study, between June and December 2009, to evaluate the interaction between anthropometric status, perceived body weight, and food consumption profiles in 1496 adolescents from public schools in Salvador, Brazil. Data on socio-epidemiological information, anthropometric status, and dietary patterns were analyzed using multidimensional statistical approaches adapted from systems biology. There were dissimilarities between anthropometric status and perception of body weight related to sex. Four dietary patterns were identified based on the food intake profile in the study participants. The distinct dietary patterns were not influenced by divergence between measured and perceived weight. Moreover, network analysis revealed that overestimation of body weight was characterized by a selectivity in ingestion of food groups that resulted in appearance of inverse correlations of consumption. Thus, misperception of body weight is associated with inverse correlations of consumption of certain food groups. These findings may aid individualized nutritional interventions in adolescents who overestimate body weight.
Effect of Porcine Placenta Extract Supplement on Skin Condition in Healthy Adult Women: A Randomized, Double-Blind Placebo-Controlled Study
Authors: Nagae Masumi , Nagata Maki , Teramoto Mitsuhiro , Yamakawa Masayuki , Matsuki Takahiro , Ohnuki Koichiro , Shimizu Kuniyoshi
Published: June 2020

Placenta extract has been used as a component of ointments for skin dryness and beautification. However, little is known about the effect of oral intake of placenta extract on skin condition. The current study aimed to clinically explore the effect of oral intake of porcine placenta extract on human skin quality. A randomized controlled double-blind trial was performed on healthy women aged 40–59 years (n = 20), who were randomly assigned to receive either placebo or 200 mg of porcine placenta extract once daily for 4 weeks from 28 January 2019 to 25 February 2019. Skin quality parameters and the Simplified Menopausal Index (SMI) were assessed at baseline and after 4 weeks. After 4 weeks, three parameters of skin quality were significantly improved in the porcine placenta group compared with the placebo group. These results suggest that porcine placenta extract can be used as a health food ingredient to maintain humans’ skin condition in the dry winter season.
Immunomodulatory and Antioxidant Properties of Wheat Gluten Protein Hydrolysates in Human Peripheral Blood Mononuclear Cells
Authors: Cruz-Chamorro Ivan , Álvarez-Sánchez Nuria , Santos-Sánchez Guillermo , Pedroche Justo , Fernández-Pachón María-Soledad , Millán Francisco , Millán-Linares María Carmen , Lardone Patricia Judith , Bejarano Ignacio , Guerrero Juan Miguel , Carrillo-Vico Antonio
Published: June 2020

Peptides from several plant food proteins not only maintain the nutritional values of the original protein and decrease the environmental impact of animal agriculture, but also exert biological activities with significant health-beneficial effects. Wheat is the most important food grain source in the world. However, negative attention on wheat-based products has arose due to the role of gluten in celiac disease. A controlled enzymatic hydrolysis could reduce the antigenicity of wheat gluten protein hydrolysates (WGPHs). Therefore, the aims of the present study were to evaluate the effects of the in vitro administration of Alcalase-generated WGPHs on the immunological and antioxidant responses of human peripheral blood mononuclear cells (PBMCs) from 39 healthy subjects. WGPH treatment reduced cell proliferation and the production of the Type 1 T helper (Th1) and Th17 pro-inflammatory cytokines IFN-γ and IL-17, respectively. WPGHs also improved the cellular anti-inflammatory microenvironment, increasing Th2/Th1 and Th2/Th17 balances. Additionally, WGPHs improved global antioxidant capacity, increased levels of the reduced form of glutathione and reduced nitric oxide production. These findings, not previously reported, highlight the beneficial capacity of these vegetable protein hydrolysates, which might represent an effective alternative in functional food generation.
The Effect of Three Mediterranean Diets on Remnant Cholesterol and Non-Alcoholic Fatty Liver Disease: A Secondary Analysis
Authors: Campanella Angelo , Iacovazzi Palma A. , Misciagna Giovanni , Bonfiglio Caterina , Mirizzi Antonella , Franco Isabella , Bianco Antonella , Sorino Paolo , Caruso Maria G. , Cisternino Anna M. , Buongiorno Claudia , Liuzzi Rosalba , Osella Alberto R.
Published: June 2020

Background: Elevated fasting remnant cholesterol (REM-C) levels have been associated with an increased cardiovascular risk in patients with metabolic syndrome (Mets) and Non-Alcoholic Fatty Liver Disease (NAFLD). We aimed to estimate the effect of different diets on REM-C levels in patients with MetS, as well as the association between NAFLD and REM-C. Methods: This is a secondary analysis of the MEDIDIET study, a parallel-arm Randomized Clinical Trial (RCT). We examined 237 people with MetS who underwent Liver Ultrasound (LUS) to assess the NAFLD score at baseline, 3-, and 6-months follow-up. Subjects were randomly assigned to the Mediterranean diet (MD), Low Glycemic Index diet (LGID), or Low Glycemic Index Mediterranean diet (LGIMD). REM-C was calculated as [total cholesterol–low density lipoprotein cholesterol (LDL-C)–high density lipoprotein cholesterol (HDL-C)]. Results: REM-C levels were higher in subjects with moderate or severe NAFLD than in mild or absent ones. All diets had a direct effect in lowering the levels of REM-C after 3 and 6 months of intervention. In adherents subjects, this effect was stronger among LGIMD as compared to the control group. There was also a significant increase in REM-C levels among Severe NAFLD subjects at 3 months and a decrease at 6 months. Conclusions: fasting REM-C level is independently associated with the grade of severity of NAFLD. LGIMD adherence directly reduced the fasting REM-C in patients with MetS.
Health Benefits of Lactic Acid Bacteria (LAB) Fermentates
Authors: Mathur Harsh , Beresford Tom P. , Cotter Paul D.
Published: June 2020

Consuming fermented foods has been reported to result in improvements in a range of health parameters. These positive effects can be exerted by a combination of the live microorganisms that the fermented foods contain, as well as the bioactive components released into the foods as by-products of the fermentation process. In many instances, and particularly in dairy fermented foods, the microorganisms involved in the fermentation process belong to the lactic acid group of bacteria (LAB). An alternative approach to making some of the health benefits that have been attributed to fermented foods available is through the production of ‘fermentates’. The term ‘fermentate’ generally relates to a powdered preparation, derived from a fermented product and which can contain the fermenting microorganisms, components of these microorganisms, culture supernatants, fermented substrates, and a range of metabolites and bioactive components with potential health benefits. Here, we provide a brief overview of a selection of in vitro and in vivo studies and patents exclusively reporting the health benefits of LAB ‘fermentates’. Typically, in such studies, the potential health benefits have been attributed to the bioactive metabolites present in the crude fermentates and/or culture supernatants rather than the direct effects of the LAB strain(s) involved.
Targeted Nutrition in Chronic Disease
Authors: Bergman Peter , Brighenti Susanna
Published: June 2020

Today, chronic disease is a major public health problem around the world that is rapidly increasing with a growing and aging population [...]
Seneca Valley Virus 3Cpro Cleaves PABPC1 to Promote Viral Replication
Authors: Xue Qiao , Liu Huisheng , Zhu Zixiang , Xue Zhaoning , Liu Xiangtao , Zheng Haixue
Published: June 2020

Seneca Valley Virus (SVV) is an oncolytic virus of the Picornaviridae family, which has emerged in recent years. The impact of SVV on host cell translation remains unknown. Here, we showed, for the first time, that SVV infection cleaved poly(A) binding protein cytoplasmic 1 (PABPC1). In SVV-infected cells, 50 kDa of the N terminal cleaved band and 25 kDa of the C terminal cleaved band of PABPC1 were detected. Further study showed that the viral protease, 3Cpro induced the cleavage of PABPC1 by its protease activity. The SVV strains with inactive point mutants of 3Cpro (H48A, C160A or H48A/C160A) can not be rescued by reverse genetics, suggesting that sites 48 and 160 of 3Cpro were essential for SVV replication. SVV 3Cpro induced the cleavage of PABPC1 at residue 437. A detailed data analysis showed that SVV infection and the overexpression of 3Cpro decreased the protein synthesis rates. The protease activity of 3Cpro was essential for inhibiting the protein synthesis. Our results also indicated that PABPC1 inhibited SVV replication. These data reveal a novel antagonistic mechanism and pathogenesis mediated by SVV and highlight the importance of 3Cpro on SVV replication.
Pharmacological Treatments for Patients with Treatment-Resistant Depression
Authors: Ruberto Valerie L. , Jha Manish K. , Murrough James W.
Published: June 2020

Over a third of patients with major depressive disorder (MDD) do not have an adequate response to first-line antidepressant treatments, i.e., they have treatment-resistant depression (TRD). These patients tend to have a more severe course of illness and are at an increased risk of suicide. Next step treatment options for patients with TRD, include switching to a different antidepressant, combining more than one antidepressant, or augmenting an antidepressant with another (non-antidepressant) medication. It is unclear which of these treatment approaches should be applied to a given patient, and in what order. Due to this ambiguity, comparing antidepressants and augmentation agents on the basis of their efficacy, tolerability, and speed of symptom relief would be beneficial for clinicians. To accomplish this, a systematic search was conducted following PRISMA guidelines. Only randomized controlled trials were included in this qualitative synthesis, resulting in 66 articles. This review identified several effective pharmaco-therapeutic strategies that are currently available for patients with TRD. Ketamine and esketamine appear to be effective for the treatment of TRD. Augmentation with certain second generation antipsychotics, such as quetiapine or aripiprazole is likewise effective, and may be preferred over switching to antidepressant monotherapy. While the combination of olanzapine and fluoxetine was one of the first pharmacotherapy approved for TRD, and its use may be limited by metabolic side-effects. Other effective strategies include augmentation with lithium, liothyronine (T3), lamotrigine, or combination of antidepressants including bupropion, tricyclics, or mirtazapine. There is insufficient research to demonstrate the efficacy of ziprasidone or levothyroxine (T4). A shared decision-making approach is recommended to guide treatment selection to address each patient’s individual needs.
Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1α
Authors: O’Dwyer Joanne , Cullen Megan , Fattah Sarinj , Murphy Robert , Stefanovic Smiljana , Kovarova Lenka , Pravda Martin , Velebny Vladimir , Heise Andreas , Duffy Garry P. , Cryan Sally Ann
Published: June 2020

Stromal-Derived Factor 1α (SDF) is an angiogenic, chemotactic protein with significant potential for applications in a range of clinical areas, including wound healing, myocardial infarction and orthopaedic regenerative approaches. The 26-min in vivo half-life of SDF, however, has limited its clinical translation to date. In this study, we investigate the use of star-shaped or linear poly(glutamic acid) (PGA) polypeptides to produce PGA–SDF nanoparticles, which can be incorporated into a tyramine-modified hyaluronic acid hydrogel (HA–TA) to facilitate sustained localised delivery of SDF. The physicochemical properties and biocompatibility of the PGA–SDF nanoparticle formulations were extensively characterised prior to incorporation into a HA–TA hydrogel. The biological activity of the SDF released from the nano-in-gel system was determined on Matrigel®, scratch and Transwell® migration assays. Both star-shaped and linear PGA facilitated SDF nanoparticle formation with particle sizes from 255–305 nm and almost complete SDF complexation. Star-PGA–SDF demonstrated superior biocompatibility and was incorporated into a HA–TA gel, which facilitated sustained SDF release for up to 35 days in vitro. Released SDF significantly improved gap closure on a scratch assay, produced a 2.8-fold increase in HUVEC Transwell® migration and a 1.5-fold increase in total tubule length on a Matrigel® assay at 12 h compared to untreated cells. Overall, we present a novel platform system for the sustained delivery of bioactive SDF from a nano-in-gel system which could be adapted for a range of biomedical applications.
Polysaccharide and Protein Films with Antimicrobial/Antioxidant Activity in the Food Industry: A Review
Authors: Jamróz Ewelina , Kopel Pavel
Published: June 2020

From an economic point of view, the spoilage of food products during processing and distribution has a negative impact on the food industry. Lipid oxidation and deterioration caused by the growth of microorganisms are the main problems during storage of food products. In order to reduce losses and extend the shelf-life of food products, the food industry has designed active packaging as an alternative to the traditional type. In the review, the benefits of active packaging materials containing biopolymers (polysaccharides and/or proteins) and active compounds (plant extracts, essential oils, nanofillers, etc.) are highlighted. The antioxidant and antimicrobial activity of this type of film has also been highlighted. In addition, the impact of active packaging on the quality and durability of food products during storage has been described.
Differential Biodegradation Kinetics of Collagen Membranes for Bone Regeneration
Authors: Toledano Manuel , Asady Samara , Toledano-Osorio Manuel , García-Godoy Franklin , Serrera-Figallo María-Angeles , Benítez-García José A. , Osorio Raquel
Published: June 2020

Native collagen-based membranes are used to guide bone regeneration; but due to their rapid biodegradation, this treatment is often unpredictable. The purpose of this study was to investigate the biodegradability of natural collagen membranes. Three non-cross-linked resorbable collagen barrier membranes were tested: Derma Fina (porcine dermis), Evolution Standard (equine pericardium) and Duo-Teck (equine lyophilized collagen felt). 10 × 10 mm2 pieces of membranes were submitted to three different degradation procedures: (1) hydrolytic degradation in phosphate buffer solution, (2) enzyme resistance, using a 0.25% porcine trypsin solution, and (3) bacterial (Clostridium histolyticum) collagenase resistance test. Weight measurements were performed with an analytic microbalance. Thickness was measured with a digital caliper. Membranes were analyzed at different time-points, up to 21 d of immersion. A stereomicroscope was used to obtain membranes’ images. ANOVA and Student Newman Keuls were used for mean comparisons (p < 0.05), except when analyzing differences between time-points within the same membrane and solution where pair-wise comparisons were applied (p < 0.001). Derma Fina attained the highest resistance to all degradation challenges. Duo-Teck was the most susceptible membrane to degradation, complete degradation occurred as soon as 8 h. The bacterial collagenase solution performed as the most aggressive test as all membranes presented 100% degradation before 21 d.
Unsupervised Satellite Image Time Series Clustering Using Object-Based Approaches and 3D Convolutional Autoencoder
Authors: Kalinicheva Ekaterina , Sublime Jérémie , Trocan Maria
Published: June 2020

Nowadays, satellite image time series (SITS) analysis has become an indispensable part of many research projects as the quantity of freely available remote sensed data increases every day. However, with the growing image resolution, pixel-level SITS analysis approaches have been replaced by more efficient ones leveraging object-based data representations. Unfortunately, the segmentation of a full time series may be a complicated task as some objects undergo important variations from one image to another and can also appear and disappear. In this paper, we propose an algorithm that performs both segmentation and clustering of SITS. It is achieved by using a compressed SITS representation obtained with a multi-view 3D convolutional autoencoder. First, a unique segmentation map is computed for the whole SITS. Then, the extracted spatio-temporal objects are clustered using their encoded descriptors. The proposed approach was evaluated on two real-life datasets and outperformed the state-of-the-art methods.
SI-traceable Spectral Irradiance Radiometric Characterization and Absolute Calibration of the TSIS-1 Spectral Irradiance Monitor (SIM)
Authors: Richard Erik , Harber Dave , Coddington Odele , Drake Ginger , Rutkowski Joel , Triplett Matthew , Pilewskie Peter , Woods Tom
Published: June 2020

The current implementation for continuous, long-term solar spectral irradiance (SSI) monitoring is the Total and Spectral Solar Irradiance Sensor (TSIS-1) Spectral Irradiance Monitor (SIM) that began operations from the International Space Station (ISS) in March 2018 and nominally provides an SSI spectrum every 12 h. Advances in both instrument design and spectral irradiance calibration techniques have resulted in the TSIS-1 SIM achieving higher absolute accuracy than its predecessor instrument in the wavelength range (200–2400 nm). A comprehensive detector-based Spectral Radiometer Facility (SRF) was developed in collaboration with the US National Institute for Standards and Technology (NIST) to ensure the ties to spectral SI standards in power and irradiance. Traceability is achieved via direct laser calibration of a focal plane electrical substitution radiometer (ESR) against a cryogenic radiometer in power and also irradiance responsivity via calibrated apertures. The SIM accuracy definition followed an absolute sensor approach based on a full radiometric measurement equation where component-level performance characterizations and calibrations were quantified with an associated uncertainty error budget and verified by independent measurements for each parameter. Unit-level characterizations were completed over the full operational envelope of external driving factors (e.g., pointing and temperature ranges) and were allowed for the independent parameterization of sub-assembly performance for expected operating conditions. Validation and final instrument end-to-end absolute calibration in the Laboratory for Atmospheric and Space Physics (LASP)-SRF achieved low combined standard uncertainty (uc < 0.25%, k = 1) in spectral irradiance.
Facilitating Inversion of the Error Covariance Models for the Wide-Swath Altimeters
Authors: Yaremchuk Max , D’Addezio Joseph M. , Jacobs Gregg
Published: June 2020

Wide-swath satellite altimeter observations are contaminated by errors caused by the uncertainties in the geometry and orientation of the on-board interferometer. These errors are strongly correlated across the track, while also having similar error structures in the along-track direction. We describe a method for modifying the geometric component of the error covariance matrix which facilitates accuracy in the removal of the respective error modes from the signal and improves computational efficiency of the data assimilation schemes involving wide-swath altimeter observations. The method has been tested using the Surface Water and Ocean Topography simulator. We show substantial computer cost savings in the pseudo-inversion of the respective error covariance matrix. This efficiency improvement comes with a few per cent error in the approximation of the original covariance model simulating uncertainties in the geometry and orientation of the on-board interferometer.
Design and Intensive Experimental Evaluation of an Enhanced Visible Light Communication System for Automotive Applications
Authors: Avătămăniței Sebastian-Andrei , Căilean Alin-Mihai , Done Adrian , Dimian Mihai , Popa Valentin , Prelipceanu Marius
Published: June 2020

As the interest toward communication-based vehicle safety applications is increasing, the development of secure wireless communication techniques has become an important research area. In this context, the article addresses issues that are related to the use of the visible light communication (VLC) technology in vehicular applications. Thus, it provides an extensive presentation concerning the main challenges and issues that are associated to vehicular VLC applications and of some of the existing VLC solutions. Moreover, the article presents the aspects related to the design and intensive experimental evaluation of a new automotive VLC system. The experimental evaluation performed in indoor and outdoor conditions shows that the proposed system can achieve communication distances up to 50 m and bit error ratio (BER) lower than 10−6, while being exposed to optical and weather perturbations. This article provides important evidence concerning the snowfall effect on middle to long range outdoor VLC, as the proposed VLC system was also evaluated in snowfall conditions. Accordingly, the experimental evaluation showed that snowfall and heavy gust could increase bit error rate by up to 10,000 times. Even so, this article provides encouraging evidence that VLC systems will soon be able to reliably support V2X communications.
A Weighted Linear Least Squares Location Method of an Acoustic Emission Source without Measuring Wave Velocity
Authors: Zhou Zilong , Rui Yichao , Cai Xin , Cheng Ruishan , Du Xueming , Lu Jianyou
Published: June 2020

The location of an acoustic emission (AE) source is crucial for predicting and controlling potential hazards. In this paper, a novel weighted linear least squares location method for AE sources without measuring wave velocity is proposed. First, the governing equations of each sensor are established according to the sensor coordinates and arrival times. Second, a mean reference equation is established by taking the mean of the squared governing equations. Third, the system of linear equations can be obtained based on the mean reference equation, and their residuals are estimated to obtain their weights. Finally, the AE source coordinate is obtained by weighting the linear equations and inserting the parameter constraint. The AE location method is verified by a pencil lead break experiment, and the results show that the locating accuracy of the proposed method is significantly higher than that of traditional methods. Furthermore, the simulation test proves that the proposed method also has a better performance (location accuracy and stability) than the traditional methods under any given scale of arrival errors.
A Novel Linear Model Based on Code Approximation for GNSS/INS Ultra-Tight Integration System
Authors: Yan Zhe , Chen Xiyuan , Tang Xinhua
Published: June 2020

The superiority of a global navigation satellite system (GNSS)/inertial navigation system (INS) ultra-tight integration navigation system has been widely verified. For those systems with centralized structure based on coherent-accumulation measurements (I/Q), the conversion from I/Q signals to navigation information is implemented by an observation equation. As a result, the model is highly complex and nonlinear, exerting essential influence on system performance. Based on the analysis of previous studies, a novel model and its linearization method are proposed, aiming at the integrity, stability and implicit nonlinear factors. Unlike the one-order precision in the common Jacobian matrix, two-order components are partly reserved in this model, which makes it possible for higher positioning accuracy and better convergence. For the positioning errors caused by ignoring code-loop deviation, a method to approximate code-phase is proposed without introducing new measurements. Consequently, the effect of code error can be significantly reduced, especially when the tracking loops are unstable. In the end, using real-sampled satellite signals, semi-physical experiments are carried out and the effectiveness and superiority of new methods are proved.
Sensitive Detection of C-Reactive Protein by One-Step Method Based on a Waveguide-Mode Sensor
Authors: Ashiba Hiroki , Oyamada Chiaki , Hosokawa Kazuya , Ueno Koji , Fujimaki Makoto
Published: June 2020

One-step biosensing methods enable the quick and simplified detection of biological substances. In this study, we developed a sensitive one-step method on the basis of a waveguide-mode sensor, which is an optical sensor utilizing waveguide-mode resonance and evanescent light. Streptavidin-conjugated and gold-nanoparticle-conjugated antibodies were reacted with a target substance and applied onto a biotinylated sensing plate. The target substance was detected by observing changes in sensor signals caused by binding the immunocomplex to the sensing surface. Performance of the developed one-step method was examined using a C-reactive protein (CRP) as a target substance. A sensor signal corresponding to the concentration of CRP was obtained. The minimal detectable CRP concentration of the developed method was 10 pM. The developed method greatly simplifies quantitative protein detection without reducing sensitivity.
Polymer Optical Fiber-Based Integrated Instrumentation in a Robot-Assisted Rehabilitation Smart Environment: A Proof of Concept
Authors: Leal-Junior Arnaldo , Avellar Leticia , Jaimes Jonathan , Díaz Camilo , dos Santos Wilian , Siqueira Adriano A. G. , Pontes Maria José , Marques Carlos , Frizera Anselmo
Published: June 2020

Advances in robotic systems for rehabilitation purposes have led to the development of specialized robot-assisted rehabilitation clinics. In addition, advantageous features of polymer optical fiber (POF) sensors such as light weight, multiplexing capabilities, electromagnetic field immunity and flexibility have resulted in the widespread use of POF sensors in many areas. Considering this background, this paper presents an integrated POF intensity variation-based sensor system for the instrumentation of different devices. We consider different scenarios for physical rehabilitation, resembling a clinic for robot-assisted rehabilitation. Thus, a multiplexing technique for POF intensity variation-based sensors was applied in which an orthosis for flexion/extension movement, a modular exoskeleton for gait assistance and a treadmill were instrumented with POF angle and force sensors, where all the sensors were integrated in the same POF system. In addition, wearable sensors for gait analysis and physiological parameter monitoring were also proposed and applied in gait exercises. The results show the feasibility of the sensors and methods proposed, where, after the characterization of each sensor, the system was implemented with three volunteers: one for the orthosis on the flexion/extension movements, one for the exoskeleton for gait assistance and the other for the free gait analysis using the proposed wearable POF sensors. To the authors’ best knowledge, this is the first time that optical fiber sensors have been used as a multiplexed and integrated solution for the simultaneous assessment of different robotic devices and rehabilitation protocols, where such an approach results in a compact, fully integrated and low-cost system, which can be readily employed in any clinical environment.
Multipoint Temperature Monitoring of Microwave Thermal Ablation in Bones through Fiber Bragg Grating Sensor Arrays
Authors: De Vita Elena , Zaltieri Martina , De Tommasi Francesca , Massaroni Carlo , Faiella Eliodoro , Zobel Bruno Beomonte , Iadicicco Agostino , Schena Emiliano , Grasso Rosario Francesco , Campopiano Stefania
Published: June 2020

Bones are a frequent site of metastases that cause intolerable cancer-related pain in 90% of patients, making their quality of life poor. In this scenario, being able to treat bone oncology patients by means of minimally invasive techniques can be crucial to avoid surgery-related risks and decrease hospitalization times. The use of microwave ablation (MWA) is gaining broad clinical acceptance to treat bone tumors. It is worth investigating temperature variations in bone tissue undergoing MWA because the clinical outcomes can be inferred from this parameter. Several feasibility studies have been performed, but an experimental analysis of the temperature trends reached into the bone during the MWA has not yet been assessed. In this work, a multi-point temperature study along the bone structure during such treatment is presented. The study has been carried out on ex vivo bovine femur and tibia, subjected to MWA. An overall of 40 measurement points covering a large sensing area was obtained for each configuration. Temperature monitoring was performed by using 40 fiber Bragg grating (FBGs) sensors (four arrays each housing 10 FBGs), inserted into the bones at specific distances to the microwave antenna. As result, the ability of this experimental multi-point monitoring approach in tracking temperature variations within bone tissue during MWA treatments was shown. This study lays the foundations for the design of a novel approach to study the effects of MWA on bone tumors. As consequence, the MWA treatment settings could be optimized in order to maximize the treatment effects of such a promising clinical application, but also customized for the specific tumor and patient.
Analysis of Strategic Directions in Sustainable Hydrogen Investment Decisions
Authors: Zhu Lu , Hu Lanli , Yüksel Serhat , Dinçer Hasan , Karakuş Hüsne , Ubay Gözde Gülseven
Published: June 2020

This study seeks to find the appropriate strategies necessary to make sustainable and effective hydrogen energy investments. Within this scope, nine different criteria are defined regarding social, managerial, and financial factors. A hesitant, interval-valued, intuitionistic fuzzy (IVIF) decision-making trial and evaluation laboratory (DEMATEL) methodology is considered to calculate the degree of importance of the criteria. Additionally, impact relation maps are also generated to visualize the causality relationship between the factors. The findings indicate that the technical dimension has the greatest importance in comparison to managerial and financial factors. Furthermore, it is also concluded that storage and logistics, research and development, and technological infrastructure are the most significant factors to be considered when defining hydrogen energy investment strategies. Hence, before investing in hydrogen energy, necessary actions should be taken to minimize the storage and logistic costs. Among them, building the production site close to the usage area will contribute significantly to this purpose. In this way, possible losses during the transportation of hydrogen can be minimized. Moreover, it is essential to identify the lowest-cost hydrogen storage method by carrying out the necessary research and development activities, thereby increasing the sustainability and effectiveness of hydrogen energy investment projects.
A Geospatial Thinking Multiyear Study
Authors: Carbonell-Carrera Carlos , Saorin Jose , Hess-Medler Stephany
Published: June 2020

In the field of environmental sustainability and landscape management, geospatial thinking is necessary. A good level of geospatial thinking is related to academic success in engineering degrees. It is relevant, therefore, to detect the possible deficiencies that university students may have in tasks related to geospatial thinking. This research presents the results of a 2014‒2019 multiyear study with agricultural engineering students, in which seven geospatial tasks were analyzed. The statistical analysis shows that geospatial tasks related to slope, stream/water flow, visibility, and relief interpretation are the best at predicting the final course mark. The present research provides quantitative data on the efficiency that four technologies have to reinforce geospatial thinking focused on each task. Augmented Reality is an appropriate 3D technology for geospatial tasks related to route search, stream/water flow, and elevation points. SketchUp Make 2017 and Autodesk 123D Make showed their potential to solve tasks related to terrain slope and visibility analysis. Spatial Data Infrastructure has given the best results in geospatial tasks related to the photointerpretation of the relief and with topographic profiles of the terrain. Our findings will help teachers to select the most appropriate geospatial tasks to include in their courses.
Student and Teacher Perceptions of Teaching Personal and Social Responsibility Implementation, Academic Performance and Gender Differences in Secondary Education
Authors: Manzano-Sánchez David , Gómez-Mármol Alberto , Valero-Valenzuela Alfonso
Published: June 2020

The aim of this study was to determine how secondary education students and teachers perceive the implementation of the Teaching Personal and Social Responsibility model (TPSR), the relationship between TPSR and marks in physical education (PE), and potential differences with regard to gender. For this purpose, TPSR was implemented for seven months and on completion 121 students (48 girls) aged between 12 and 16 from the first and third grade of secondary education were asked to complete the TPSR perception questionnaire (ECVA-12) to determine their satisfaction with this methodology and the values the model promoted in pupils. Moreover, the participant teachers were also interviewed. Results showed positive student perceptions of the implemented methodology and its promotion of values, and significant differences in academic performance in PE in favor of males. Teachers valued this methodology very positively and considered that it would be useful with any kind of student. This paper suggests the importance of TPSR implementation for all teachers, regardless of their specialism, and considers that there may be potential in engaging other collectives such as families.
A Study on the Effects of Entrepreneurial Orientation and Learning Orientation on Financial Performance: Focusing on Mediating Effects of Market Orientation
Authors: Cho Yun Hee , Lee Joo-Heon
Published: June 2020

The primary purpose of this article was to examine the mediating effects of market orientation on the relationship between entrepreneurial orientation and financial performance. The mediation effects of market orientation on the relationship between learning orientation and financial performance were also investigated. One hundred and seventy-four valid survey questionnaires were collected from Korean entrepreneurs, who were searching for angel investments or business consultants for growth. Our unique research design allowed us to test the mediating effects of the dimensions of market orientation between the dimensions of entrepreneurial orientation and financial performance. The most important research results are as follows. First, the innovative-proactiveness dimension of entrepreneurial orientation has a statistically significant effect on financial performance, but the risk-taking propensity dimension does not significantly affect financial performance. Second, the customer orientation dimension of market orientation fully mediates the relationships between innovative-proactiveness and financial performance. Second, the competitor orientation dimension of market orientation shows a partial mediating effect on the relationship between innovative-proactiveness and financial performance. Third, learning orientation does not significantly affect financial performance. To increase financial performance, growth-seeking entrepreneurs need to improve customer orientation, competitor orientation, and innovative-proactiveness.
Danube Cruise Tourism as a Niche Product—An Overview of the Current Supply and Potential
Authors: Jászberényi Melinda , Miskolczi Márk
Published: June 2020

Tourism in the 21st century is being re-shaped by constant changes in consumer trends. The Danube, Europe’s second-longest river, has rich potential for tourism over its whole course, and river cruises offer superb opportunities to explore. This study aims to provide a comprehensive picture of the most important characteristics of cruise tourism on the Danube. In our research, a literature review (LR) and content analysis (CA) were used to examine trends in the inland waterway cruise sector, which, despite the growing interest in the product, is still not deemed to be a part of mass tourism. Danube cruise tourism relies heavily on alternative (niche) tourism features, which satisfy both cultural and authentic tourism preferences. Currently, many elements of niche tourism are missing from the product supply, but, with a modest addition of such features, the demand for the product could increase and its economic performance in the period following the expected recession would be enhanced.
Traditional Agroforestry Systems and Conservation of Native Plant Diversity of Seasonally Dry Tropical Forests
Authors: Rendón-Sandoval Francisco J. , Casas Alejandro , Moreno-Calles Ana I. , Torres-García Ignacio , García-Frapolli Eduardo
Published: June 2020

Traditional agroforestry systems (TAFS), which integrate crops with wildlife, are important reservoirs of human culture and technical experiences with a high capacity for biodiversity conservation. Our study aimed to evaluate the capacity of TAFS to conserve the floristic diversity of tropical dry forests (TDF) in the Tehuacán-Cuicatlán Valley, Mexico. We compared TAFS and TDF by measuring their forest cover, floristic composition, and structure, in addition to documenting the motivations of people to maintain native vegetation in their agricultural fields. We conducted a restricted randomized sampling of perennial plant species, including nine sites of TAFS and nine of TDF to determine the alpha, beta, and gamma diversity. Furthermore, we conducted semi-structured interviews with peasants who managed the agricultural plots we studied. We also performed workshops with people of the communities where surveys were performed. Our findings show that TAFS can maintain, on average, 68% of the species (95% of them native to the region) and 53% of the abundance of individuals occurring in the adjacent TDF. TAFS harbour 30% (39 species) of plants endemic to Mexico. Total species richness of TDF and TAFS were similar, as well as the effective number of species or communities estimated for the alpha, beta, and gamma diversity, but differed in the abundance of individuals. The high species turnover recorded in TDF (72%) and TAFS (74%) has profound implications for conservation, suggesting that it would be necessary to maintain several sites in order to conserve the regional diversity of native vegetation. Material, non-material, and regulatory contributions were reported to be the reason that peasants take into account maintaining natural vegetation. TAFS associated with TDF in the region (also called “Apancles”) contain an important richness, diversity, and endemism of components of natural ecosystems, as well as provide multiple socio-ecological contributions. These systems could represent a viable alternative to reconcile biological conservation with social well-being.
Simulation of Human Activity Intensity and Its Influence on Mammal Diversity in Sanjiangyuan National Park, China
Authors: Xi Changbai , Chi Yao , Qian Tianlu , Zhang Wenhan , Wang Jiechen
Published: June 2020

The rapid pace of development in western China has brought about inevitable concerns for environmental conditions and their management. The Sanjiangyuan National Park strives to address concerns for sustainable water resources management and biodiversity management, especially for the protection of endangered flora and fauna. In this study, a machine learning model (MaxEnt) was used to predict the human activity intensity and its effects on species in Sanjiangyuan protected by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). The model used human settlements as input and datasets such as terrain factors, climate, and artificial structures as environmental factors. The results showed that human activity intensity was significantly different between the East and the West. The area with the highest human activity intensity was Yushu County in the south area, and Xinghai-Zeku County in the east. By comparing the mammal richness with human activity intensity, we found human–wildlife coexistence in Sanjiangyuan. A detailed analysis on the CITES protected species showed that many important species, such as snow leopards, red pandas, and small Indian civets, occupied areas with high human activity intensity. The national park protects 3/4 CITES species with 1/3 in the area of the Sanjiangyuan region, owing to the relatively low human activity intensity.
“May the Smoke Keep Coming Out the Fireplace”: Moral Connections between Rural Tourism and Socio-Ecological Resilience in the EUME Region, Galicia
Authors: Álvarez Bibiana Martínez , Cortes-Vazquez Jose A.
Published: June 2020

For several decades, tourism has been considered an important instrument for the sustainable development of rural areas. However, a great deal of scholarship has cast a doubt on the actual economic and ecological impacts of many of these initiatives. Acknowledging these critiques, we argue in this paper that a more accurate examination of the implication of rural development projects based on tourism should not merely look at the number of overnight stays or the income generated, but also at the multiple, subtle and complex implications of tourism for socio-ecological resilience. In order to do this, we argue, it is crucial to pay attention to the moral values underpinning tourism practices. Through an ethnographic analysis of the material, symbolic and experiential transformations brought about by a number of tourism initiatives in a rural region in Galicia, our goal is to discuss the complex connections between the promotion of this new activity, the diversification of the local economy, and the social reproduction of local communities and their specific forms of human-environment engagements.
A Weighted and Directed Perspective of Global Stock Market Connectedness: A Variance Decomposition and GERGM Framework
Authors: Zhang Yizhuo , Chen Rui , Ma Ding
Published: June 2020

The financial penetration accelerated by economic globalization and financial liberalization has inevitably induced market co-movement and the rising likelihood of cross-market risk contagion. An in-depth analysis concerning the carrier of risk contagion, i.e., market connectedness network, is of great significance for risk management. This study aims to establish a holistic framework to shed light on the topological dynamics and the evolving channels of connectedness network among 24 major stock markets in two aspects; namely, a dynamic perspective juxtaposing crisis and non-crisis periods, and a contrasting perspective between risk absorption and risk spillover. To this end, a methodological framework of the generalized variance decomposition and generalized exponential random graph models (GERGM) is constructed, in which the former method formulates the asymmetric causal relationships of stock return volatility among countries and regions into weighted and directed networks, and the latter method simulates and models the varying attributes of different contagion channels in the formation of tie directions and weights. The results indicate that the global stock market network reflects typical event-driven and time-varying characteristics. Countries and regions that rely heavily on foreign direct investment (FDI) are more likely to absorb risks, especially during the post-crisis recovery period, while countries and regions with higher foreign portfolio holdings are more inclined to risk spillover, especially during the subprime crisis. Geographical proximity and bilateral trade volume amplify risk contagion, whereas foreign exchange reserve holding improves robustness. This holistic framework allows the identification of the direction and intensity of risk contagion and the clarification of priority of risk transmission channels in different stages, thus reducing the uncertainty of risk management and providing insights into the macro-prudential managements toward sustainable economic development.
Postharvest Management of Grains in Haiti and Gender Roles
Authors: Quellhorst Hannah E. , Njoroge Anastasia , Venort Taisha , Baributsa Dieudonne
Published: June 2020

Food security is a continuing challenge in Haiti. The demand for food far exceeds local supply. As a result, Haiti imports nearly 50% of its national food needs. Postharvest management is an often neglected link in the grain value chain that has potential to improve food availability. We interviewed 214 farmers in three departments in July–August 2017 to assess postharvest handling and storage of grains and gender roles in Haiti. Results showed that among the respondents: 64% were male; 55% were over the age of 40 years; and about half had attended secondary school. Maize and beans were the most grown and stored crops. The average production for maize and beans was 288 kg and 88 kg, respectively. About 75% of the respondents stored less than 100 kg of either crop. Rodents and insects were the main causes of loss during storage. Farmers who produced more grain, stored longer, and experienced losses during drying and seed storage were more likely to use insecticides on stored products. Postharvest management practices were gendered at the lower end of the value chain; where women played a key role in marketing the grain. Addressing postharvest management challenges, through targeted interventions, to increase food availability while investing in maize and bean production can improve food security in Haiti.