bluuebunny/crossref_metadata_2025 huggingface dataset:
Identity Restoration Project in Novaya Drama: Focusing on Representation of Narrative Self in I. Vyrypaev’s drama
Authors:   Institute for Russian and Altaic Studies, CBNU, Yoon Seo Hyun
Published: September 2023

This study aims to analyze the narrative structure and the narrator-character's feature of Ivan Vyrypaev's drama as a part of a wide-ranging attempt to explain characteristics of Novaya drama, which has at its core the problem of the construction of the narrative self and the restoration of identity.
Vyrypaev's early plays, including , , and , represent the mental wanderings of modern people through the provocative subjects, intermittent scene changes, and the narrator-character's fast rap-text. These works reveal the situation of mental wandering and existential crisis of modern people who are allowed all pleasures. In his later works, in the case of , , , , and , the composition of the characters, the subject matter, and the situation begin to take on an ordinary, usual feature, while at the same time, relationships with others and their inability to communicate are presented as main topics. And finally the narrator-characters of Vyrypaev’s recent works, , , and  are composed of characters such as interviewers, interviewees, and conference attendees, so that the theater is presented as a place for contemporary encounters that includes the audience. Vyrypaev’s insight that modern audiences come to the theater not to see Shakespeare’s Hamlet, but to listen to the stories of their contemporary writers and actors awakens the perception of the essence of the theatre that should not be forgotten in the feast of various media.
The Role of Environmental Legal Instruments and Government Policies in Realizing Sustainable Development in Indonesia
Authors: Pelengkahu Muhammad Rahjay , Satria Najib
Published: September 2023

The increasing human needs have encouraged massive development in various countries, both developing and developed countries. in its progress, a development that is often carried out intersects with the environment. Also, various cases of pollution and environmental destruction due to development have been rampant. Therefore, a new paradigm in development is needed, which is contained in the concept of sustainable development. However, this requires the role of environmental law and government policies so that the goals of sustainable development can be realized. Sustainable development has the aim of balancing economic interests and environmental conservation so that the current development does not have a negative impact on future generations of humans. In general, the government has three types of policies in the environmental sector, namely, policies that are preemptive, preventive, and proactive. The writing of this law refers to a qualitative approach with a qualitative descriptive type of research. Through this research method, it is hoped that this legal writing will explain the role of law and government policy in realizing sustainable development in Indonesia. research results show The goal of sustainable development is to realize the development and utilization of natural resources to improve the quality of human life, without compromising the welfare of future human generations.
Uji Toksisitas Subkronik Ekstrak Etanol Daun Sungkai (Paronema canescens Jack.) Terhadap Tikus Putih Rattus noverticus (Wistar strain)
Authors: Muharni Muharni , Ferlinahayati Ferlinahayati , Fitrya Fitrya , Eliza Eliza , Yohandini Heni , Cenora Cindy
Published: September 2023

Tumbuhan sungkai (Paronema canescens Jack)  merupakan salah satu tumbuhan obat tradisional yang telah digunakan  untuk pengobatan berbagai penyakit.  Penggunaan suatu tumbuhan obat harus teruji keamanannya, terutama untuk penggunaan jangka panjang.  Pada penelitian ini telah dilakukan uji  toksisitas subkronis ekstrak etanol  daun P. canescens menggunakan  30 ekor tikus  putih jantan Rattus noverticus (Wistar strain), Penelitian ini menggunakan 5 kelompok hewan terdiri dari kelompok kontrol, kelompok perlakuan dosis 100, 200, 400, dan 800 mg/kg berat badan (bb) . Percobaan  dilakukan selama 28 hari. Parameter yang diamati meliputi hematologi darah, biokimia darah, makroskopik organ, berat organ relatif dan histopatologi organ hati dan ginjal. Hasil pengukuran menunjukkan  tidak terdapat perbedaan yang signifikan (p>0.05) antara kelompok kontrol dengan kelompok perlakuan untuk semua parameter hematologi maupun biokimia darah.  Analisa histopatologi juga menunjukkan tidak terdapat gejala kerusakan pada organ hati dan ginjal.  Hal ini mengindikasikan ekstrak daun sungkai tidak memberikan efek toksik pada hewan uji.
Efek Samping Obat Gefitinib pada Pasien Kanker Paru dengan Epidermal Growth Factor Receptor (EGFR) Mutasi Positif
Authors: Parwatininghati Ni Putu , Rahmawati Fita , Sajinadiyasa I Gede Ketut
Published: September 2023

Deteksi mutasi Epidermal Growth Factor Receptor (EGFR) pada pasien kanker paru akan membantu dalam pemilihan targeted therapy yaitu gefitinib. Studi mengenai evaluasi profil keamanan gefitinib di Indonesia sangat terbatas sehingga penelitian ini bertujuan untuk mengetahui efek samping obat hematologi dan non hematologi dari gefitinib pada pasien kanker paru dengan EGFR mutasi positif. Rancangan penelitian adalah observasional cross sectional. Data sekunder diambil melalui rekam medis tahun 2020 sampai 2022 pada 44 pasien. Probabilitas efek samping obat diukur dengan Naranjo Adverse Drug Reaction Probability Scale dan tingkat keparahan efek samping obat dinilai menggunakan Common Terminology Criteria for Adverse Events (CTCAE). Hasil penelitian menunjukkan efek samping hematologi yang paling sering muncul adalah anemia grade 1 pada 18 pasien (40.91%). Pada efek samping non hematologi, rash grade 2 mendominasi pada 20 pasien (45.46%), 14 pasien (31.82%) mengalami peningkatan serum transaminase grade 1, diare grade 1 terjadi pada 5 pasien (11.36%) dan mual muntah grade 2 dialami oleh 3 pasien (6.82%). Total 36 pasien (81.82%) mengalami efek samping dengan 19 kejadian termasuk kategori possible dan 17 kejadian termasuk kategori probable. Efek samping yang muncul bersifat ringan, dapat ditangani dan tidak kumulatif. Tidak didapatkan penyesuaian dosis atau penghentian penggunaan obat yang disebabkan oleh efek samping obat.
Pelatihan Penyusunan Laporan Keuangan BUMDes Bintang Muda Mandiri, Desa Sialang Kubang, Kecamatan Perhentian Raja, Kampar, Riau
Authors: Komalasari Sanda Patrisia , Oktavia Fitriyeni , Albar Berri Brilliant , Amsal Ares Albirru
Published: September 2023

This financial report training activity aims to improve the quality of Bintang Muda Mandiri BUMDes financial reporting. Training in preparing financial reports is necessary because, based on the observations made, many accounts still need to be by the transactions. In addition, the format of the report also still needs improvement. Observations of the existing financial reports and interviews regarding the accounts in the financial statements were first carried out. The training content was compiled, and the training was carried out. This activity was attended by BUMDes employees, especially those who have an interest in financial reporting. Mistakes found during observations were corrected to achieve the appropriate financial statements. The financial statements to be prepared consist of an income statement, a statement of changes in equity, and a statement of financial position. This community service activity results in an increase in the quality of the Bintang Muda Mandiri BUMDes financial reports.
Sosialisasi Pengelolaan Teaching Farm Pembibitan Kakao Unggul pada Kelompok Tani Kakao se-Kota Padang
Authors: Obel Obel , Martinsyah Rachmad Hersi , Armansyah Armansyah , Sitepu Meisilva Erona , Busniah Munzir , Yanti Yulmira , Lina Eka Candra , Ramadhan Nugraha
Published: September 2023

Cocoa is a plantation commodity that is essential to the Indonesian economy. There are still many problems in cocoa cultivation found in the field, such as using poor-quality seedlings. One of the ways to do this is by taking preventive action by providing immunity induction from the seedling stage. Immunity induction can be done by utilizing Rhizobacteria, arbuscular mycorrhizal fungi, Entomopathogenic fungi, and vegetable pesticides. The Faculty of Agriculture of Universitas Andalas collaborated with the entrepreneurs through a Ministry of Education and Culture program, Matching Fund 2022, to make an innovation, namely the Teaching Farm for superior cocoa nurseries. This activity aims to socialize the cocoa nursery teaching farm in the hope of helping farmers prepare high-quality and sustainable cocoa seeds. This community service activity has been carried out at the Padang City Agriculture Office. The conclusions of this activity include: a) The community service program made by the Teaching Farm Team of Universitas Andalas is by the needs of the farmer group; the farmer group is satisfied and feels this service activity was helpful for the development of the Cocoa farmer group in the future, b) enrichment of understanding of farmer group members regarding biofertilizers and vegetable pesticides.
Sosialisasi dan Demonstrasi Pemberian Vitamin B Kompleks untuk Kambing di Peternakan Ashar Farm Kota Payakumbuh
Authors: Fajrona Kadran , Ferawati Ferawati , Suhartati Linda , Suharto El Latifa Sri
Published: September 2023

Ashar Farm is a goat farming business in Balai Cacang Village, North Payakumbuh District, Payakumbuh City, West Sumatra, Indonesia. It was established in 2020 with a starting population of 30 goats. An intensive maintenance system has been applied. The condition of the farm is currently experiencing a population decline; as many as 17 goats are kept. The population decline is due to a lack of appetite for livestock, resulting in death. So far, the farmer provides only forage without adding appetite-enhancing supplements such as vitamin B complex as animal feeding. It assumes that there needs to be more nutrition for the goats. On the other hand, a Vitamin B complex can increase livestock productivity—the community engagement activity aimed to provide knowledge and skills of breeders about administering Vitamin B complex. The method of this activity was carried out by socialization and demonstrations using the Vitamin B complex as an additive in feed. As a result of this activity, Ashar Farm farmers gain new knowledge to overcome the lack of appetite for livestock and how to inject vitamin B complex into the goats so that their livestock business can be more productive.
Setembro amarelo e prevenção ao suicídio
Authors: Silva Filho Humberto Corrêa da , Agostinho Fabiano Rosa , Meleiro Alexandrina
Published: September 2023

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Transgêneros
Authors: Abdo Carmita Helena Najjar , Spizzirri Giancarlo , Silva Antonio Medeiros Peregrino da
Published: September 2023

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50 Anos da ABP e dia do psiquiatra
Authors: Psiquiatria Associação Brasileira de
Published: September 2023

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The Image of a Fountain in the Selected Lyrics of Pernette du Guillét and Maurice Scève
Authors: Prikhod'ko Kseniya Olegovna
Published: September 2023

The article is dedicated to the image of a fountain – or a spring – in the lyrics of the poets of the Lyon School Pernette du Guillet and Maurice Scève. A clear spring as a symbol of love became widely known thanks to “The Romance of the Rose”, a French allegorical poem of the 13th century. The article provides a comparative analysis of selected lyrics by Pernette du Guillet and Maurice Scève, mostly from poetry collections “Rymes” and “Délie”. The purpose of the study is to compare the artistic motifs and imagery built by the poets around a fountain, which is a significant topos of courtly poetry. For this purpose, detailed comparative analysis of the lyrics of Maurice Scève, the head of the Lyon School of Poets, and Pernette du Guillet, his student, is carried with the help of poems with the image of a fountain. The novelty of the study is attributed to the fact that the lyrics of Pernette du Guillet with its problems and interpretation are practically unexplored in Russian literary studies. “Délie” by Scève is analyzed and interpreted in the dissertation of V.P. Avdonin dated 2013. The lyrics of Lyon poets' and the comparison of the concepts of love philosophy are topical themes in Russian literary studies. A fountain has several guises in the studied poems. The first is the healing from the fire of pernicious passion that can be found in its waters. While the water does save the lyrical heroine of Pernetta from the flames (as can be seen in the elegy plot), Scève pictures inextinguishable flames (continuing to burn even in water). They both – in their own way based on their gender roles – touch upon the motif of a naked lady bathing, which traces back to the myth of Actaeon. The fountain water is a soul mirror and a vessel of divine wisdom, it is an intermediary between a lover and a loved one.
STAJe−: A Supersonic Flight Program STAJe− 1 Payload Design and System Study
Authors: Kunze Jens , Vijay Shelar Sampada , Paull Allan
Published: September 2023

The [Formula: see text] flight program is the latest implementation of a university-based supersonic and hypersonic flight-test program. In the first flight, which is the subject of this study, the focus is on evaluating the suitability of commercial off-the-shelf electronic hardware, additively manufactured internal payload structures, and a long-range communications technique in the challenging environment presented by flight at high supersonic Mach numbers. These items can significantly reduce the cost of a flight experiment, and thus lower the threshold for flight experimentation. The scientific objectives of this flight are to collect pressure and temperature data on the whole trajectory to compare to numerical models, to optically measure the temperature of composite fins mounted on the payload, and to eject the flight module from the rocket assembly and track its location for subsequent recovery. Design calculations for the tracking system are presented alongside experimental results from ground tests demonstrating the suitability of the system. Furthermore, a one-dimensional calculation of the external wall temperatures over the trajectory is presented, which shows that internal systems are sufficiently protected from the harsh environment. Although the materials are shown to be appropriate for the flight, a layer of cork will be added to parts of the payload to further reduce the chance of structural failure. In addition, it is shown that a pneumatic ejection system is suited to overcoming the drag forces on the front of the rocket to initiate separation.
Critical Decay Time Model for Direct Detonation Initiation Energy in Gaseous Mixtures
Authors: Liu Yuen , Xie Qing , Chen Yuxuan , Mével Rémy , Ren Zhuyin
Published: September 2023

A critical decay time (CDT) model is developed to predict the critical energy of direct detonation initiation in gaseous mixtures. It is based on the global initiation criterion that the energy deposit should allow the decaying shock speed to stay in a specific range below the Chapman–Jouguet (CJ) speed at least for a critical decay time. The speed range is estimated with the sub-CJ Zel’dovich–von Neumann–Döring (ZND) simulations. The critical decay time is calculated as the minimum time to reach unity Mach number in the sub-CJ ZND simulations. The lower-speed bound is taken as a characteristic extinction speed below (which means the lower-speed bound) which the direct initiation should fail. This speed is calibrated using one-dimensional simulations for [Formula: see text] mixtures. The calibrated CDT model is then applied to estimate the critical initiation energy with the point-blast theory. The model yields better agreement with experimental data for hydrogen-fueled mixtures such as [Formula: see text] and [Formula: see text] mixtures than the well-known critical decay rate model. For small hydrocarbon-fueled mixtures such as [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] mixtures, the predicted critical energies also agree well with experimental results. The CDT model provides an efficient tool to evaluate the detonability of fuel–oxidizer mixtures, which could be beneficial for ignition initiation in propulsion and power devices such as rotating detonation engines.
Mean Flow Characteristics Downstream of a Vortex Tube Separator Array
Authors: Acharya Adit S. , Lowe K. Todd , Ng Wing F.
Published: September 2023

Vortex tube separator (VTS) arrays are used to filter foreign particles from turboshaft engine intakes. Arrays may consist of hundreds of separators that share a common surrounding plenum, potentially allowing for significant interactions between the devices. However, most VTS studies have been limited to individual separators acting alone. The current study first involves an experimental investigation of the fluid flow emerging from the outlets of a VTS array installed in a wind tunnel. Particle image velocimetry is used to measure the flowfield at planes [Formula: see text], [Formula: see text], and [Formula: see text] downstream of the outlets, where [Formula: see text] is the inlet tube diameter of a separator. The results indicate that the emerging vortices quickly merge into a single vortex with high circumferential velocity concentrated near the edges of the duct, and that a central recirculation zone (CRZ) develops. This is in contrast to the flow from a single VTS, which does not have a clear CRZ. Comparisons to similar combustion swirler flows lead to the hypothesis that VTS arrays may uniquely generate fast-developing CRZs that produce strong axial flow gradients near or even within some VTS outlets. Such gradients will alter the filtration performance of affected VTSs, which is highly sensitive to flow rates. To explain the onset of recirculation that is exclusive to the array configuration, the framework of a momentum integral model has been developed and is presented here. Additionally, computer-aided design files of the experimental geometry along with inlet/outlet boundary conditions are being made available for any future computational validation studies of this complex flowfield.
Hybrid Lattice Boltzmann Approach for Simulation of High-Speed Flows
Authors: Li Wende , Wang Junye , Gopalakrishnan Pradeep , Li Yanbing , Zhang Raoyang , Chen Hudong
Published: September 2023

A lattice Boltzmann approach utilizing hybrid lattices for accurate simulation of high-speed transonic (TS) flows is presented in this study. Single-layer lattice models, such as D3Q19, are computationally efficient with low numerical dissipation, but are limited to simulate weakly compressible flows within subsonic Mach regime. Multilayer lattice models, such as D3Q33, are capable of simulating thermal and high-speed compressible flows in TS Mach regime, but suffer from a higher numerical dissipation and higher computational cost. To take full advantages of these two types of lattices, a simulation domain is divided into two regions, high-subsonic (HS) flow regions to be solved by single-layer lattices and TS flow regions to be solved by multilayer lattices. The interface connecting the HS and TS flow regions are represented by double-sided surfels to realize smooth flow transition and ensure satisfaction of fundamental conservation laws. The hybrid lattice Boltzmann approach is stable and robust, and it allows multiple HS/TS flow regions with arbitrary shapes. Extensive validation studies demonstrate that the proposed approach is capable of obtaining accurate aerodynamic prediction of flows with a wide range of Mach numbers, and preserving the low numerical dissipation advantage of single-layer lattices in aeroacoustic computations.
Resources and performance rates of medical organizations providing medical care in the field of dermatovenereology in the Russian Federation in 2016–2022
Authors: Kubanov Alexey A. , Bogdanova Elena V.
Published: September 2023

The paper describes changes in resources and performance of medical organizations providing medical care in the field of dermatovenereology in 20162022. The dynamics of the main rates of the service was analyzed, and the rates achieved in 2022 were compared with those before the pandemic of a new coronavirus infection. The rates of the provision of the population of the Russian Federation with dermatovenereologists, 24-hour and daytime dermatovenereological beds are presented. The analysis of the volumes of dermatovenereologic medical care dynamics provided in outpatient, inpatient and day hospital conditions was carried out. The dynamics of incidence of sexually transmitted infections is described, contribution of syphilis cases among foreign citizens to syphilis rates is presented. The changes in prevalence and incidence rates of diseases of the skin and subcutaneous tissue, as well as atopic dermatitis, psoriasis, contact dermatitis, other dermatitis, localized scleroderma, and discoid lupus erythematosus are analyzed.
Valorización de la investigación en universidades mexicanas: el caso de los Programas de Estímulos a la Innovación
Authors: Maldonado-Sada María
Published: September 2023

La investigación es un elemento primordial para las políticas globales y el desarrollo económico de una región. El objetivo de este estudio fue presentar un modelo que caracteriza la valorización de la investigación en las universidades de México, tomando en cuenta aquellos factores para propiciarla o incrementarla, con base en la experiencia de investigadores de Instituciones de Educación Superior en Tamaulipas, que participaron en alrededor del 50% de los proyectos aprobados dentro de los Programas de Estímulos a la Innovación (PEI) de sus respectivas universidades. El alcance del presente trabajo es de tipo exploratorio dado el contexto nacional, utilizando una metodología cualitativa y la teoría fundamentada con entrevistas semiestructuradas. Los resultados obtenidos muestran que las universidades públicas de México presentan dos tipos de factores: los que incrementan la valorización, como la intención de la investigación, la motivación del investigador y la relación con la industria; y los que la limitan, como el contexto nacional, las características institucionales y la investigación sin transferir. Se discuten estos hallazgos en el contexto nacional comparando con parámetros internacionales. Se propone para investigaciones futuras, comparar y contrastar los resultados encontrados con el sector industrial y el sector público, para enriquecer el modelo presentado en este estudio.
On the utility of the extracted ion chromatograms for assigning the conjugation sites in bioconjugates synthesized by the maleimide-thiol chemistry
Authors: González Luis Javier , Pousa Satomy , Ramos Pablo E. , Besada Vladimir , Carvalho Paulo , Kurt Louise , Batista Michel , Soares Rodrigo , Leyva Alejandro , Durán Rosario , Murillo Dhayme , Fajardo Abel , Garay Hilda Elisa , Rodríguez-Mallón Alina , Takao Toshifumi
Published: September 2023

Maleimide-thiol chemistry is widely used to synthesize antibody-drug conjugates and conjugate vaccines. The set of MS/MS spectra automatically assigned to proteolytic type 2 peptides with a thiosuccinimide linker and its stabilized products (thiazine and hydrolyzed species), contains valuable information on the conjugation sites. Sample processing before LC-MS/MS analysis transforms the thiosuccinimide linker into its stabilized products. The MS/MS spectra of type 2 peptides must be validated based on objective criteria. The extracted ion chromatogram (XIC) has not been considered previously for this purpose. In the LC-MS/MS analysis, linear peptides eluted in a one-fraction XIC as expected. On the contrary, depending on the analyzed proteolytic digestion, the type 2 peptides with a thiazine linker were detected in 77-100 % of the cases with a two-fraction XIC pattern, probably composed by a mixture of diastereomers. Type 2 peptides with the hydrolyzed thiosuccinimide linker were detected with a mixed-pattern XIC in two, three and four elution fractions in 77 %, 15 % and 8 % of the cases, respectively. The four-fraction XIC pattern is probably composed by the full-chromatographic separation of type 2 peptides cross-linked by two positional isomers of the thiosuccinamic acid linker containing a chiral carbon. Tandem digestions increased the number of type 2 peptides detected with a multiple-fractions XIC pattern. XIC of proteolytic peptides is a relevant source of information considered for data validation. Transcyclization and hydrolysis not only stabilize the thiosuccinimide linker but also permit, together with XIC, a more reliable identification of the conjugation sites by LC-MS/MS analysis.
Two-Dimensional Infrared Spectroscopy of Isolated Molecular Ions
Authors: Ma Zifan , Chen Liangyi , Xu Chuzhi , Fournier Joseph
Published: September 2023

Two-dimensional infrared (2D IR) spectroscopy of mass-selected, cryogenically cooled molecular ions is presented. Nonlinear response pathways, encoded in the time-domain photodissociation action response of weakly-bound N2 messenger tags, are isolated using pulse shaping techniques following excitation with four collinear ultrafast IR pulses. 2D IR spectra of Re(CO)3(CH3CN)3+ ions capture off-diagonal cross-peak bleach signals between the asymmetric and symmetric carbonyl stretching transitions which display intensity variations as a function of pump-probe delay time due to coherent coupling between the modes. Well-resolved 2D IR features in the congested fingerprint region of protonated caffeine (C8H10N4O2H+) are also reported. Importantly, intense cross-peak signals are observed at 3 ps waiting time, indicating that tag-loss dynamics are not competing with the measured nonlinear signals. These demonstrations pave the way for more precise studies of molecular interactions and dynamics that are not easily obtainable with current condensed-phase methodologies.
Cool Carriers: Triplet Diffusion Dominates Upconversion Yield
Authors: Sullivan Colette , Kuszynski Jason , Kovalev Alexey , Siegrist Theo , Schaller Richard , Strouse Geoffrey , Nienhaus Lea
Published: September 2023

Perovskites have gained popularity both as the active material in photovoltaics and as bulk triplet sensitizers for solid-state triplet-triplet annihilation upconversion (TTA-UC). Prior to widespread implementation into commercial photovoltaics an in-depth understanding of the environmental influences on device performance is required. To this point, the temperature dependent structure-function properties of TTA-UC within methylammonium formamidinium lead triiodide (MAFA)/rubrene UC devices are explored. A strong temperature dependence of the underlying UC dynamics is observed, where the maximum UC efficiency is achieved at 170 K reflecting the competition between triplet diffusion length, diffusion rate, and triplet-triplet encounter events. A combination of spectroscopic and structural methods and theoretical modelling illustrates that despite the significantly increased carrier lifetime of the perovskite at low temperatures, the TTA-UC dynamics are not governed by the underlying sensitizer properties but rather limited by the underlying triplet diffusion.
The arginine methyltransferase PRMT5 promotes mucosal defense in the intestine
Authors: Hernandez Juan E , Llorente Cristina , Ma Shengyun , Miyamoto Kiana T , Sinha Saptarshi , Steele Scarlet , Xiao Zihui , Lai Ching-Jung , Zuniga Elina I , Ghosh Pradipta , Schnabl Bernd , Huang Wendy Jia Men
Published: September 2023

PRMT5 is a type II arginine methyltransferase abundantly expressed in the colonic epithelium. It is up-regulated in inflammatory bowel disease and colorectal cancer. However, its role in mucosal defense against enteric infection has not been studied. Here, we report thatPrmt5in the murine colon is up-regulated in response toCitrobacter rodentiuminfection. Pathogen clearance in mice with haploinsufficient expression ofPrmt5is significantly delayed compared with wildtype littermate controls. Transcriptomic analyses further reveal that PRMT5 regulates the expression of canonical crypt goblet cell genes involved in mucus production, assembly, and anti-microbial responses via methyltransferase activity–dependent and –independent mechanisms. Together, these findings uncover PRMT5 as a novel regulator of mucosal defense and a potential therapeutic target for treating intestinal diseases.
PERBAIKAN KUALITAS DAYA MENGGUNAKAN OPTIMAL CAPACITOR PLACEMENT (OCP) PADA SISTEM KELISTRIKAN PT. FMC AGRICULTURAL MANUFACTURING
Authors: Sari Navynda Kurnia
Published: September 2023

Kualitas daya dalam sistem tenaga merupakan hal yang sangat penting dan harus diperhatikan untuk menjaga stabilitas dan continuitas sistem tenaga listrik dalam suatu industri. Diantara permasalahan kualitas daya yang timbul salah satunya adalah penurunan nilai faktor daya (power faktor) yang menyebabkan konsumsi daya menjadi berlebih. Seperti pada industri-industri besar pada umumnya. PT. FMC Agricultural Manufacturing juga memiliki permasalahan kualitas daya pada sistem kelistrikannya, disebabkan karena mempunyai banyak motor-motor berkapasitas besar untuk proses produksinya yang dapat menyebabkan rugi-rugi daya semakin meningkat. Untuk mengantisipasi hal tersebut perlu dilakukan pengontrolan daya reaktif salah satunya dapat dilakukan dengan pemasangan kapasitor yang optimal untuk memperbaiki dan meningkatkan faktor daya sehingga dapat memaksimalkan kapasitas penyaluran daya sistem. Pada penelitian ini dibahas studi kasus perbaikan kondisi faktor daya pada sistem kelistrikan PT. FMC Agricultural Manufacturing. Perbaikan faktor daya dilakukan dengan metode Optimal Capacitor Placement (OCP) untuk memperbaiki kondisi faktor daya dan mereduksi rugi-rugi daya pada saluran. Dari hasil penelitian, diketahui lokasi pemasangan kapasitor yang tepat untuk memperbaiki nilai faktor daya pada sistem berdasarkan hasil analisis aliran daya pada software ETAP 12.6.0 yaitu pada bus 3 dengan nilai kompensasi daya reaktif adalah sebesar 91.51 kVAR dan arus 115.06 A.
La Conferencia Arbitral del Ocume de 1935: Los coloniales frente al suministro nacional de madera
Authors: Guerra Juan Carlos
Published: September 2023

In 1935, okoume was the main wood extracted from the Spanish colonies in the Gulf of Guinea. Its commercialization fed the tropical wood flows of the Hamburg market along with a conflict that had been incubating between forest concessionaires in the colony and Spanish plywood and board/lumberindustrialists, concerning limits to the supply of the national market. The conflict became so intense in the first months of 1935 that it forced the mainland colonial administration to convene the Okoume Arbitration Conference. The documentation from the conference is of considerable interest for understanding how a part of the colonial economy was inserted into the mainland economy. It uncovers the logics and strategies that unfolded around the use of a tropical wood as well as the features of the veneer and board sector: a little-known industry linked to colonial realities.
Analysis of spatial variation of soil cover moisture along the front of the sprinkling machine
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Zeyliger A. M. , Zatinatsky S. V. , Ermolaeva O. S. , Kolganov D. A.
Published: September 2023

In order to study the spatial relationships between the distribution of moisture in the 0‑5 cm layer of soil cover and the distribution of local irrigation rates along the pressure front of the sprinkler, a study was carried out, including the measurement of moisture along this front, as well as subsequent data analysis. Moisture measurement was carried out at the soybean sowing site, sprinkling of which was carried out by SM «Kaskad». The analysis of the results included statistical and geostatistical processing of measurement data, as well as analysis of the results of computer modeling of zonal irrigation norms and their comparison with zonal values of humidity. As a result of the analysis, the relationship between the influence of the uneven distribution of local irrigation norms on the formation of spatial patterns of moisture of the surface 0‑5 cm layer of soil cover was revealed. At the same time, it was shown that, despite the revealed correlation between the zonal values of humidity and the zonal values of irrigation norms, there are still a number of factors and conditions that could have a significant impact.
Assessment of the condition of underground engineering structures of the reclamation system using humidity maps obtained from remote sensing data of the earth by the DJI Phantom 4 Multispectra unmanned aerial vehicle
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Kristina Sergeevna K. S.
Published: September 2023

Reclamation system is a complex of engineering structures and devices that ensure the creation of the required water, air, thermal and nutrient regimes of soils. The composition of reclamation systems includes underground pipelines, drains, hydraulic structures that may fail and require repair, but it is impossible to detect a problem area without monitoring the area of the system by antediluvian methods or conducting survey work. The purpose of the work: to justify the use of soil moisture maps obtained by the DJI PHANTOM 4 MULTISPECTRA UAV to identify problem areas of the reclamation network or vice versa absence. Aerial photography was carried out in May 2021 on the treated section of the drainage and humidification network of the Yakhrom floodplain of the Moscow region. As a result of the survey, a digital relief model, an operational humidity map based on the calculated NDWI water index were obtained. The flight altitude of the quadcopter was 180 m above the earth’s surface, the pixel size of the image of the earth’s surface to be 7.9 cm. According to the results of aerial photography on the selected site, the absolute marks of the earth’s surface vary from 134.67 to 135.23. On average, the slope of the earth’s surface of the selected site is 0.002 in the direction from northwest to southeast. There are no pronounced microforms of relief moisture in the surface layer of the soil obtained in the field corresponds to the variety of color areas of the NDWI water indices highlighted on the operational humidity map. In the soil conditions of the studied area, the moisture content of the surface soil layer is logarithmic with the normalized difference water index NDWI. The correlation coefficient is 0.9 ± 0.06, which indicates a very high relationship between the studied indicators. Such a map can be used to identify problem areas of the reclamation network.
Fabrication of ciprofloxacin loaded alginate/cockle shell powder nanobiocomposite bone scaffold
Authors: Wong Huai Li , Santhanam Jacinta , Ng Shiow Fern , Bharatham B Hemabarathy
Published: September 2023

Orthopedic implant infection is one of the most challenging issues in bone tissue engineering industry. Hence, local delivery of antibiotics incorporated into a fabricated bone scaffold possibly provides a more rapid bacteria inhibitory effect. In this study, pure ciprofloxacin loaded alginate/cockle shell powder nanobiocomposite bone scaffolds are fabricated with 5 wt% and 10 wt% ciprofloxacin respectively and tested for drug encapsulation, drug release and antibacterial properties towards common implant infecting bacterial strains (Staphylococcus aureus and Pseudomonas aeruginosa). Results from the studies showed a low drug encapsulation and drug release regardless of the concentration of drugs loaded with no significant differences noted (p<0.05). However, bacterial inhibition studies through direct contact and using eluted samples from drug release studies showed some inhibitory effects towards the growth of both bacterial strains tested. These findings were further justified with microscopy observations on biofilm and bacterial colony formation. Mineralization studies conducted additionally indicated that the scaffolds characteristics was not compromised due to drug loading. Although pure ciprofloxacin may not be the most suitable antibiotic to be incorporated into the nanobiocomposite bone scaffold, the study did provide some insight to the possible use of the scaffold for future drug delivery applications.
Hubungan antara Perceived Organizational Support dengan Readiness for Change pada Dokter Gigi di Bandung dan Cimahi
Authors: Hidayat Marlianti , Andamari Stephanie , Gusriani Gusriani
Published: September 2023

Dokter gigi merupakan salah satu tenaga kesehatan yang rentan terhadap penularan Covid-19 saat melakukan pelayanan kesehatan sehingga ditetapkanlah prosedur pelayanan kesehatan yang baru. Kesiapan dokter gigi untuk berubah menjadi penting untuk membantu terlaksanya prosedur kesehatan baru secara optimal dan berkesinambungan. Salah satu hal yang dapat mendukung kesiapan untuk berubah adalah penghayatan dokter gigi terhadap dukungan dari instansi tempat mereka melakukan pelayanan kesehatan. Tujuan penelitian ini untuk mengetahui hubungan perceived organizational support (POS) dengan readiness for change (RFC) pada dokter gigi dalam melakukan pelayanan kesehatan di era pandemi Covid-19. Metode penelitian yang digunakan adalah uji korelasi dengan Pearson’s Correlation. Alat ukur berupa kuesioner yang disusun oleh peneliti berdasarkan teori POS (Eisenberger, 1986) dan RFC (Holt, et al., 2007). Terdapat 107 dokter gigi dari Bandung (86.9%) dan Cimahi (13.1%) yang ikut berpartisipasi dalam penelitian ini. Hasil penelitian menunjukkan bahwa POS signifikan berhubungan secara positif dengan RFC pada dokter gigi. Dalam penelitian ini, POS juga signifikan berkorelasi secara positif dengan tiga aspek RFC. Organisasi yang dihayati mendukung dapat meningkatkan kesiapan untuk berubah pada dokter gigi dalam melakukan pelayanan kesehatan di era pandemi Covid-19 ini.
Effectiveness of Cognitive Behavior Group Therapy to Reduce Social Anxiety in Stuttering Adults
Authors: Adani Erizza Farizan , Kurniawan Afif
Published: September 2023

Adults seeking treatment for stuttering presented a comorbid diagnosis of social anxiety. The development of social anxiety may be related to negative conditioning experiences from an early age regarding people’s responses when reacting to stuttering such as confusion, interrupting, mocking, distancing, or ignoring stuttering speech. Repeated exposure to negative social reactions causes people who stutter to form beliefs that negative evaluations will occur in all social situations. The high level of social anxiety is more concerning given the data showing that increased anxiety can increase the frequency of stuttering. The purpose of group therapy with Cognitive Behavior Therapy is to reduce social anxiety and negative thoughts related to social anxiety in stuttering adults. The method used is a quantitative method supported by qualitative data from interviews. The results showed a decrease in social anxiety and negative thoughts in the group’s average score after undergoing therapy. In addition, there were changes in behavior, thoughts, and feelings after the session as evidenced from the follow-up interview a month after the end of therapy.
Productive Parenting Model on Adolescent in Bandung
Authors: Theresia Ellen , Edwina O. Irene Prameswari
Published: September 2023

Parents are significant figures for children and have a crucial role to build children's character, especially through parenting. When children become teenagers, parents also need to adjust the parenting given. The parenting focus of the research is productive parenting, which is a parenting pattern with warmth, acceptance, firm and clear control, demands according to the child's age, being responsive and making children the main priority. Purpose of this study is to develop a factor model of productive parenting as a construct, based on the integration of aspects: high parental acceptance and warmth, moderate to high restrictiveness, insistence on mature behavior, high responsiveness, and high positive involvement. Researchers adds parental modeling as an important aspect of productive parenting. Based on 816 participants, our CFA displays all aspects High parental acceptance and Warmth, moderate to high restrictiveness, Insistence on mature behavior (demand), High responsiveness, High positive involvement and Parental modeling, are constructs of productive parenting.
Faktor -faktor yang Memengaruhi Internet Gaming Disorder pada Remaja di Era Teknologi Modern: Literature Review
Authors: Adhyaksa Ida Bagus Danandinatha , Valentina Tience Debora
Published: September 2023

Pada era teknologi modern, perkembangan teknologi memberikan dampak yang besar dalam penggunaannya. Masyarakat dapat mengakses segala jenis informasi dan berita dengan cepat dan mudah. Remaja sangat sering terpapar oleh teknologi dan perkembangannya. Remaja menggunakan internet dalam mengakses informasi secara cepat, media hiburan, dan bermain game online. Perilaku bermain game online yang kompulsif dan tidak dapat diatur dengan sedemikan rupa akan menyebabkan kecanduan pada game online atau yang sering disebut dengan Internet Gaming Disorder. Internet Gaming Disorder merupakan perilaku bermain game secara persisten yang menyebabkan kerusakan pada kegiatan sehari – hari. Tentunya Internet Gaming Disorder perlu dijadikan prioritas dalam pencegahan dan penanganannya oleh remaja. Metode yang digunakan pada artikel ini adalah literature review. Literature Review ini bertujuan untuk melihat faktor – faktor apa saja yang dapat mendukung atau memengaruhi terjadinya Internet Gaming Disorder pada remaja. Kajian literatur secara deskriptif dilakukan pada 10 artikel yang menggunakan penelitian kuantitatif dengan metode sampling yang beragam dan responden remaja. Hasil penelitian literatur menunjukan terdapat faktor – faktor yang memengaruhi internet gaming disorder pada remaja yaitu motif gaming, kecemasan sosial, motivasi dan dukungan sosial, kesepian dan kebutuhan berafiliasi, sensation seeking, pola asuh orangtua, attention problem, tingkat stres, internet escapism, kontrol diri. Kesimpulan pada artikel ini adalah dalam pertumbuhannya, remaja harus mengembangkan self-control pada diri sendiri sehingga dapat mencegah terjadinya internet gaming disorder.
Strengthening Destination Branding Through Local Product Innovation in Watusigar Village, Ngawen, Gunungkidul
Authors: Wiyatiningsih Wiyatiningsih , Seliari Tutun , Stefia Cheryl Marlitta , Hapsari Maria Kinanthi Sakti Ning , Kore Angelica Riwu
Published: September 2023

Kalurahan Watusigar, which declared itself a conservation village, has a strategic location as the main access point for tourists from the north and east to the tourism area in Gunungkidul Regency, offering the opportunity to pioneer a green tourism village. The local community of Kalurahan Watusigar has initiated various initiatives through collaboration with relevant stakeholders. One such collaboration, with the Research and Community Service Institution of Duta Wacana Christian University (LPPM UKDW), is a community service activity aimed at strengthening destination branding through training for local product innovations of eco prints. The selection of eco print products is based on the availability of plants in the Watusigar area that can be used as natural dyes. The objective of this community service activity is to focus on developing the branding of Kalurahan Watusigar as a conservation village and green tourism village through local product innovation using natural materials and marketing strategies in accordance with digital technology. The target audience for this activity is the community members and Karang Taruna members of Kalurahan Watusigar. This community service activity introduces the eco print product ecosystem, which is the value chain of eco print products starting from creation, production, distribution, consumption, and conservation, utilizing action research methods through training, discussions, and workshops. The result of this community service activity is the expansion of knowledge about plants and materials in the environment to be used as environmentally friendly craft products. The eco print product innovation is an essential step in creating a creative economy ecosystem in Kalurahan Watusigar.
Mujeres en la academia: experiencias sobre el SNI y el capitalismo académico
Authors: Gutiérrez Aceves Patricia Esmeralda , Echeverría Echeverría Rebelín
Published: September 2023

El capitalismo académico describe la transformación de las universidades hacia un modelo empresarial. Los efectos que ha traído a las comunidades universitarias son diversos, pero resalta la desigualdad por género. El objetivo es analizar las experiencias compartidas por un grupo de académicas sobre el Sistema Nacional de Investigadores (SNI). Estos son los resultados de un estudio sobre el capitalismo académico en una universidad pública del sur de México, realizado con una metodología fenomenológica y utilizando entrevistas semiestructuradas. En general, las académicas coinciden en que pertenecer al SNI es una importante distinción, la cual representa un alto costo para ellas en términos de la productividad y el tiempo que demanda, además de enfrentar dilemas relacionados con el trabajo de cuidados u otras decisiones vitales, como ser madres o tener pareja. El análisis revela que aún hay mucho por hacer en relación con las políticas educativas en México desde una perspectiva de género.
EDUCATION IN CIVIL ENGINEERING THROUGH JOURNALS PUBLICATIONS: THE RELATION BETWEEN THE PUBLICATION TIME AND ITS REGIONAL RANKINGS
Authors: Emmanuel Oluwasegun V.
Published: September 2023

The fast and quality dissemination of research breakthroughs via journals is essential to the researchers. Hence, this study analyzed the average duration for Civil Engineering journals based on the points allocations in Poland’s Ministry of Science and Higher Education (MEiN) list. A total of 30 journals were randomly selected and grouped based on the regional points allocation. The date of submission to the date of acceptance (SA) and the date of acceptance to the date of publication (SP) were extracted from 3557 articles. Version 26 IBM Statistical Packages for Social Sciences (SPSS) was used to analyze the average duration for the dataset. Multivariate Analysis of Variance (MANOVA) was used for the analysis of the relationship between the points allocation and the Scopus impact factors (IF), Web of Science impact factors (WoS IF), source normalized impact per paper (SNIP), SA, and SP. The results show that the average duration SA and SP for journals with 200, 140, and 100 points within the 5 years are 305.28, 285.25, 317.93 days, respectively, while for journals with 70, 40, and 20 points, the average duration is 180.50, 324.60, 206.41 days. Further analysis shows a statistically significant difference between the Scopus IF, WoS IF, SNIP, and allocated points. They indicate that these journal metrics affect journal categorization.
Guías de manejo de la psoriasis en Colombia: compromiso de todos
Authors: Velásquez Margarita María
Published: September 2023

Tenemos el gusto de presentar las guías de manejo basadas en la evidencia para el manejo de la psoriasis en Colombia, fruto del liderazgo académico del grupo colombiano de psoriasis, ColPsor y Asocolderma, el trabajo dedicado y comprometido del equipo editorial conformado por Ángela Londoño, Carolina Cortés y César González, y un grupo multidisciplinario de autores, entre estos, dermatólogos, re umatólogos y representantes de los pacientes. La fundamentación metodológica estuvo a cargo del Instituto para la Evaluación de la Calidad y Atención en Salud, y la evaluación previa a la publicación, de pares académicos de reconocida trayectoria nacional e internacional. Los aspectos metodológicos y técnicos fueron evaluados y validados de forma independiente, por el Instituto de Evaluación Tecnológica en Salud (IETS).
¿Reconoce esta clave diagnóstica?
Authors: Rodríguez Gerzaín
Published: September 2023

Un campesino de 53 años de edad consultó por presentar una placa verrugosa, prominente en el dorso de la mano derecha, de nueve meses de evolución, que tenía aspecto tumoral. No era dolorosa y comenzaba a presentar focos de ulceración. El paciente notó que aumentaba gradualmente de tamaño.