bluuebunny/crossref_metadata_2025 huggingface dataset:
Morphological and Physiological Responses of Two Penstemon Species to Saline Water Irrigation
Authors: Nepal Prakriti , Wang Zirui , Carnahan McKenna , Maughan Wes , Hershkowitz Julie , Sun Youping , Paudel Asmita , Forsyth Kyle , Volesky Nick , Devkota Ananta Raj , Chen Ji Jhong
Published: April 2024

Penstemon, with more than 250 species native to North America, holds significant aesthetic and ecological value in Utah, supporting diverse pollinators. Despite their significance, the survival of penstemon is threatened by challenges such as habitat loss, climate change, and Utah’s naturally high soil salinity. To address these challenges and understand their adaptability, this study evaluated the salt tolerance of two penstemon species [Penstemon davidsonii (Davidson’s penstemon) and Penstemon heterophyllus (foothill penstemon)] under controlled greenhouse conditions. The aim was to develop baseline information for nursery production and landscape use that utilize reclaimed water for irrigation. Plants were irrigated weekly with a nutrient solution at an electrical conductivity (EC) of 1.0 dS·m−1 as control or a saline solution at an EC of 2.5, 5.0, 7.5, or 10.0 dS·m−1 for 8 weeks. Half of the plants were harvested after four irrigation events, and the remaining plants were harvested after eight irrigation events. At harvest, visual rating (0 = dead and 5 = excellent without foliage salt damage), plant width, number of shoots, leaf area, shoot dry weight, leaf greenness [Soil Plant Analysis Development (SPAD)], stomatal conductance, and canopy temperature were collected to assess the impact of salinity stress. In both species, salt damage was dependent on the salinity levels and length of exposure. After four irrigation events, both species exhibited foliage damage that increased in severity with rising EC. The most severe damage was observed in plants receiving saline solution at an EC of 10.0 dS·m−1. After eight irrigation events, P. davidsonii exposed to a saline solution with an EC of 10.0 dS·m−1 received a visual rating of 0, whereas P. heterophyllus had a visual rating of 0.4. Both species exhibited salinity-induced effects, with variations observed in the specific parameters and the degree of response. Penstemon davidsonii exhibited significant salinity stress, as indicated by reduced leaf area, shoot dry weight, SPAD reading, and stomatal conductance with increasing EC of the saline solution. In addition, in both species, at both harvests, canopy temperatures increased either linearly or quadratically by 8% to 36% as the EC levels of the saline solution increased. These results indicate that P. davidsonii was more sensitive to salinity stress than P. heterophyllus.
The Vanishing Hamartia and the Destiny of Struggle in Modern Tragedy: Riders to the Sea
Authors:   British And American Language And Literature Association Of Korea, Kim Min
Published: April 2024

This paper analyzes the specific characteristics of classical tragedies and the essence of tragedy in modern drama, mainly focusing on John Millington Synge’s Riders to the Sea. Arthur Miller defined the possibility of modern tragedy as the tragic experience of the common man in relationship to the environment. However, in the modern era, the environment is often represented or segmented by capitalism, leading to the misconception that modern tragedy may be succinctly defined by the struggles of ordinary people facing continuous situational hardships in pursuit of their dreams. In contrast, Synge’s tragic drama Riders to the Sea (first performed in 1904), which this paper observes, is grounded in an isolated natural setting while still remaining connected with the realm of the divine or the universe. Focusing on the phase of vanishing hamartia, the escape from guilt of the subjects, and the expansion of the concept of necessity from outer to their inner sphere, this paper argues how classic tragic essence is also manifested in modern plays, provoking profound thoughts among the audience and elevating their souls through elegant suffering and intellectual clarification in its own way. In its characteristic of stillness, where the conclusion is drawn out over an entire lifetime of struggle and disguised to obscure emotional suffering beneath a veneer of pessimism or idealism, the modern tragic drama establishes its own tragic genre with catharsis and magnitude. This contributes to a deeper level of meaningful understanding in the lives of all ordinary people in the contemporary world.
Intersections of Identity: Race, Legacy, and Belonging, within Caryl Phillips’s Historical Narrative “Dr Johnson’s Watch” as Part of Three English Lives
Authors:   British And American Language And Literature Association Of Korea, Lee Seogkwang
Published: April 2024

This essay examines Caryl Phillips’s portrayal of the historical figure Francis Barber. This formerly enslaved person rose to become the companion and heir of Samuel Johnson, the renowned lexicographer and writer. Phillips’s narrative, ‘Dr. Johnson's Watch,’ encapsulates two pivotal episodes from Barber’s life: his poignant attendance at Johnson's funeral in Westminster Abbey and his encounter with an unnamed narrator years later in Lichfield. Through these episodes, Phillips delves into profound themes of race, identity, belonging, and legacy against the backdrop of eighteenth-century England, a society entrenched in slavery and colonialism. The essay offers a nuanced literary analysis of the complex relationship between Johnson and Barber, both of whom existed as outsiders within their own contexts. It prompts reflection on the representation and agency of black individuals in history and literature, grappling with the challenges and opportunities they confronted in a largely hostile and indifferent society. At its thematic core lies Johnson’s watch, symbolising the enduring connections between individuals of diverse backgrounds and underscoring the legacy of figures like Johnson in advocating against the injustices of slavery. Through Phillips's narrative, the essay elucidates the intricate dynamics of race, power, and belonging in English society, shedding light on the struggles faced by immigrants and marginalized individuals during this tumultuous period. Ultimately, ‘Dr. Johnson’s Watch’ serves as a powerful testament to the humanity and dignity of Barber and other foreigners, inviting readers to contemplate the enduring impact of historical figures in advocating for justice and equality.
Prediction of enzyme action for extraction of antimicrobial substances from Sus scrofa and Bos taurus
Authors: Polishchuk E. K. , Kotenkova E. A.
Published: April 2024

The study of antimicrobial compounds of animal origin, particularly antimicrobial peptides (AMPs), is a current research topic. However, extracting endogenous AMPs is a challenging process and requires the application of targeted enzymatic processing principles based on knowledge of the structure of prepropeptide molecules — precursors of AMPs. In this study, a search was conducted for antimicrobial peptides present in Sus scrofa and Bos taurus organisms, as well as their precursors, using The Antimicrobial Peptide Database and UniProtKB databases. In the amino acid sequences of prepropeptides, the sequences of the mature peptides were found, and cleavage sites for trypsin, bacterial collagenase (type I), and neutrophil elastase were determined. As a result of the search for antimicrobial compounds in The Antimicrobial Peptide Database, 18 antimicrobial peptides from Sus scrofa and 40 antimicrobial peptides from Bos taurus were identified. Based on the results of determining cleavage sites in AMP precursors, enzymes were ranked from less preferred to more preferred for AMP release as follows: bacterial collagenase (type I) ≤ trypsin < neutrophil elastase. This order is justified not only by the number of suitable cleavage sites and their accuracy but also by the action of enzymes within mature AMPs: it is important to consider that enzymes can “cut” the peptides themselves, thereby reducing their antimicrobial activity. The bioinformatics analysis conducted is applicable for both primary screening of raw material potential and determining of suitable enzymes for extracting antimicrobial compounds from Sus scrofa and Bos taurus organisms.
lexible sensors for food monitoring. Part II: Applications
Authors: Luo D. , Nikitina M. A. , Xiao X.
Published: April 2024

Monitoring and maintaining food quality, safety, and authenticity are the most important concerns in the food industry. The cutting-edge flexible sensors for food monitoring precisely satisfy the needs of acquiring information on multiple parameters in a small space, they provide for the more reasonable layout, get data on the mechanical deformations, and can be conformably attached to arbitrarily curved surfaces. The flexible sensing materials with a large area of specific surface, that ensure high mobility and density of the media, feature dense active sites, outstanding adjustability and high processing capacities, such as two-dimensional carbon nanomaterials, conductive polymers, and nano-hybrid materials; those materials have further improved the sensitivity, stability and selectivity of the flexible sensors’ perception. This article attempts to critically review the present state-of-arts developments in relation to the materials, manufacturing techniques and sensing mechanisms of the devices, as well as the applications of the electrically-transduced flexible sensors. Moreover, this article elaborates on the transduction mechanisms of the several typical transducers, with a focus on the physics behind, including the modulation of the doping level, Schottky barrier, and interfacial layer that typically cause changes in conductivity, functionality and permittivity. We also highlight the benefits and the technical challenges along with the appropriate solutions provided by the presented flexible sensors, and we also consider the potential strategies that allow overcoming limitations in power consumption, quantitatively assess the trade-offs in maintaining the quality and marketability, to optimize wireless communication and explore new sensing patterns.
Måleegenskaper ved den norske versjonen av Mood and Feelings Questionnaire- Humøret Ditt (MFQ)
Authors: Richter Jörg , Sund Anne Mari
Published: April 2024

Beskrivelse: Humøret Ditt er et selvutfyllingsskjema som måler barns og unges (8-18 år) depressive symptomer i henhold til DSM-III-R (DSM-IV). Spørreskjemaet har 34 spørsmål med tre svaralternativer. De unge blir spurt om hva vedkommende har følt eller tenkt i løpet av de siste to ukene. Testskår er beregnet ved å summere enkeltskårer. Kompetansekrav for bruk av Humøret Ditt inkluderer generell opplæring i testbruk, samt yrkesstatus som psykolog, lege, annet helsepersonell med utdanning på mastergradsnivå, spesialpedagog eller pedagog med mastergrad.
Litteratursøk: Vårt systematiske litteratursøk etter dokumentasjon for de psykometriske egenskapene til MFQ identifiserte 30 referanser fra norske studier: tre artikler stammet fra prosjektet Norwegian Universal Preventive Program for Social Anxiety (NUPP-SA), 20 var basert på studien ‘Ungdom og psykisk helse’ ved NTNU i Trondheim, og sju var basert på den korte versjonen av Humøret Ditt.
Psykometri: Det er ikke rapportert normer i de inkluderte artiklene, men normer for aldersgruppen 13–15 år kan fås fra oversetteren bak den norske versjonen av MFQ, Anne Mari Sund (NTNU). Intern konsistens og test-retest reliabilitet er rapportert som meget god. Konvergerende validitet er rapportert som god ved en høy korrelasjon mellom MFQ-skårer og skårer på Beck Depression Inventory (BDI), med relevante skalaer angst-depresjons syndrom, med internaliserende symptomer, og med aggressive symptomskala fra Youth Self Report. God diskriminerende validitet er vist ved lav korrelasjon med sosial ønskelighetsskala (YSR).
Konklusjon: Det foreligger god dokumentasjon på psykometriske egenskaper som begrepsvaliditet, konvergerende validitet og reliabilitet for Humøret Ditt, men bare for aldersspektrum 13-15 år og fra et begrenset område i Norge. Derfor kan det anbefales å bruke MFQ blant norske 13-15 år gamle ungdommer i forskning, både i epidemiologiske studier og studier av kliniske utvalg.
Måleegenskaper ved den norske versjonen av The Leyton Obsessional Inventory Child Version (LOI-CV)
Authors: Skarphedinsson Gudmundur , Valderhaug Robert
Published: April 2024

Beskrivelse: Leyton Obsessional Inventory for Children (LOI-CV) er et spørreskjema for å kartlegge symptomer på tvangslidelse (OCD) hos barn og ungdom. Spørreskjemaet inneholder 20 testledd. Barnet eller ungdommen skal først angi om symptomet er til stede eller ikke tilstede. Dersom symptomet er tilstede skal de vurdere alvorlighetsgraden på en skala fra 1 til 3. Spørreskjemaet er utarbeidet av Carol Zaremba Berg og hennes kolleger, og det ble først publisert i 1988. Originalversjonen har vist god indre konsistens for alle barn og god test-retest stabilitet for aldersgruppen 11-16 år. Eldre studier viste god kriterievaliditet men nye studier har vist dårligere kriterievaliditet som kan indikere svak diagnostisk nøyaktighet. Den norske versjonen er oversatt av Knut Gundersen, Lars T. Jørgensen og Luke Moynahan. Den kan fritt benyttes av bokens eier, men det er ikke spesifisert kompetansekrav til de som skal anvende testen.
Litteratursøk: Det finnes en dansk studie hvor LOI-CV er brukt, og som rapporter skårer på LOI-CV hos 1032 barn og unge i alderen 11-17 år valgt ut fra en normalbefolkning.
Psykometri: Det foreligger ingen dokumentasjon av måleegenskapene hverken ved den norske, danske eller svenske versjonen av testen.
Konklusjon: Vårt litteratursøk viste at det ikke foreligger noen dokumentasjon av måleegenskapene ved den norske versjonen. Vi anbefaler brukere av den norske versjonen å være svært forsiktige i bruk og tolkning av LOI-CV.
Måleegenskaper ved den norske versjonen av Strengths and Difficulties Questionnaire, lærerrapport (SDQ-T)
Authors: Kornør Hege , Heyerdahl Sonja
Published: April 2024

Beskrivelse: Strengths and Difficulties Questionnaire (SDQ) er et sett spørreskjema for utfylling av foreldre, lærere og barn. SDQ ble opprinnelig utgitt på engelsk av Robert Goodman i 1997. I 1999 kom de norske versjonene, basert på en oversettelse og tilbakeoversettelse ved Einar Heiervang og kolleger. Robert Goodman eier rettighetene til testen. Lærerversjonen (SDQ-T) har 25 ledd fordelt på fem delskalaer. Det er et skjema som skal fylles ut av lærere for å kartlegge psykiske helse, vennerelasjoner og prososial atferd hos barn i alderen 4-17 år. Det tar noen få minutter å fylle ut. Forskere, klinikere og pedagoger kan administrere og tolke SDQ-T. Litteratursøk: Våre systematiske søk etter dokumentasjon for måleegenskapene ved den norske versjonen av SDQ-T førte til 252 treff, hvorav 22 publikasjoner fra ni studier ble inkludert. I alt 18 av publikasjonene rapporterte fra store befolkningsstudier i Bergen, Trondheim, Bodø, Østfold og Oslo-området. Psykometri: De store befolkningsstudiene bidro med regionale normdata for aldersgruppene 4 år og 7-9 år. I to av studiene undersøkte forskerne faktorstrukturen til SDQ-T, og tre studier rapporterte verdier for diagnostisk nøyaktighet. Gruppesammenlikninger mellom subgrupper og kontrollgrupper belyste også validiteten ved instrumentet, spesielt resultater for ulike diagnostiske grupper. Vi fant mål på indre konsistens (Cronbachs alfa) fra sju studier. Konklusjon: SDQ-T har regionale normdata, men bare for barn under 9 år, og nasjonale data mangler. Forventede gruppeforskjeller og konfirmatoriske faktoranalyser støtter opp under instrumentets begrepsvaliditet. Skalaene har gjennomgående tilfredsstillende til god indre konsistens. Evnen til å fange opp barn med en psykiatrisk diagnose synes å være ganske god. Likevel er ikke den diagnostiske nøyaktighet så god at SDQ-T kan anbefales som universelt screening-instrument. Den norske versjonen av SDQ-T kan være egnet til å screene for psykiatriske diagnoser i selekterte utvalg med risiko for psykiske helseproblemer.
Måleegenskaper ved den norske foreldreversjonen av Behavior Rating Inventory of Executive Function (BRIEF)
Authors: Sørensen Lin , Hysing Mari
Published: April 2024

Beskrivelse: Behavior Rating Inventory of Executive Function (BRIEF) er et foreldreutfylt spørreskjema for barn i alderen 5-18 år. Det brukes som mål på overordnete kognitive kontrollfunksjoner i hverdagen, betegnet som eksekutive funksjoner. Det er utviklet av Gioia, Isquith, Guy, & Kenworthy (2000) og oversatt til norsk av Nicholas og Hermansen (2004), og senere revidert av Fallmyr, Ekerholt og Nicholas (2007). Man må ha lisens fra rettighetshaver PAR, inc. for å kjøpe og bruke BRIEF.
Litteratursøk: Seks norske artikler inneholdt relevant psykometrisk informasjon og ble inkludert i vurderingen.
Psykometri: Det eksisterer ikke norske normer. Det er støtte for bruk av amerikanske normer da disse normene lå innenfor for 95 % konfidensintervallet for skårene i et norsk utvalg. Validiteten til instrumentet er støttet av at det er signifikante forskjeller mellom barn i kliniske grupper, og mer spesifikt ADHD fra jevnaldrende. Det er også vist god begrepsvaliditet da BRIEF er moderat til høyt korrelert med andre sammenlignbare spørreskjemamål. Det er en lav til moderat sammenheng med eksekutive funksjonstester.
Konklusjon: De psykometriske egenskapene er undersøkt i til sammen seks norske artikler. Det eksisterer ikke norske normer, men den eksisterende litteraturen viser at den norske versjonen har gode psykometriske egenskaper.
Genetic structure and molecular analysis of the species of the genus Artemisia L. (Asteraceae) distributed in Azerbaijan
Authors: Sadıgova Narmin , Suleymanova Zarifa , Ojaghi Javid , İbadullayeva Sayyara , Mammadov Alamdar
Published: April 2024

In this study, the phylogenetic relationships and genetic structure of 10 collected genotypes of Artemisia szowitziana (Besser) Grossh and Artemisia fragrans Willd. species from different regions of Azerbaijan were investigated using RAPD primers. A total of 94 amplicons were amplified using selected RAPD primers. Among them 3 band with OPA-02 primers and 12 band with OPW-17 primers were amplified. The highest polymorphism among the investigated RAPD markers was 100, 90.91 and 90%, which has been obtained by OPW-17, OPT-19, and OPT-20 primers, respectively. However, the calculated average value of polymorphism was as high as 72.79% based on 10 different RAPD markers. The average PIC (Polymorphism Information Content) value (0.864) has indicated the rich genetic diversity among the studied samples. The cluster analyses by using Jaccard similarity index and UPGMA method classified all Artemisia L. samples into 6 major groups. Principal Component Analysis (PCA) justified 74.22% of the total variance. Based on the results obtained, it has been observed that there is a wide range of diversity in the molecular level between the population of Artemisia szowitziana (1-2 and 4-6 samples) and Artemisia fragrans (3, 5, 7 and 8, 9, 10 samples) and between population of the Artemisia species in Azerbaijan.
“Pai Dulu, Yuk!”: Meninjau Inkulturasi Budaya Tionghoa—Jibbok, Maisong, Sangseng, Cengbeng dalam Kekristenan di Indonesia Kaitannya dengan Model Teologi Kontekstual Menurut Bevans dan Klasifikasi Terkait Christ and Culture Menurut Niebuhr
Authors: Chang Carmela , Listijabudi Daniel Kurniawan
Published: April 2024

AbstractNow, Contextual Theology has become a “primary need” for humanity as an effort to understand their faith (in this case, the Christian faith) from the context of a particular era. Stephen B. Bevans, an American theologian, wrote models of contextual theology, one of which is the translation model. In addition, Niebuhr’s ideas of Christ and Culture have also contributed to religious and cultural practices in Indonesia. In reality, contextual theology is not that easy to apply in people’s daily lives. There are many differences, and if applied, the applications vary. A true story of a series of funerals in Chinese culture related to Jibbok, Maisong, Sangseng, Cengbeng, which are inculturated with the characteristics and liturgy of Christianity. What wasthe beginning of this? Why did the church end up “absorbing” such cultural practices? It is true that many Chinese crossbreed people in Indonesia embrace Christianity and thus implement Christian liturgy to Chinese culture which may or may not be in line with Christian values. However, which one comes first? Culture or religion?
Abstrak Kini, Teologi Kontekstual menjadi “kebutuhan primer” umat manusia sebagai upaya memahami iman mereka (dalam hal ini iman Kristen) dari konteks zaman tertentu. Stephen B. Bevans, seorang teolog Amerika, menuliskan model-model teologi kontekstual, salah satunya adalah model terjemahan. Selain itu, gagasan Niebuhr mengenai Christ and Culture juga turut memberi kontribusi terhadap praktik-praktik beragama dan berbudaya di Indonesia. Kenyataannya, berkontekstual tidak semudah itu diterapkan dalam kehidupan keseharian umat. Banyak perbedaan, dan jika diterapkan, penerapannya berbeda-beda. Sebuah kisah nyata dari rangkaian ritual kedukaan dalam budaya Tionghoa terkait Jibbok, Maisong, Sangseng, Cengbeng, yang terinkulturasi dengan karakteristik juga liturgi dalam Kekristenan. Apa yang menjadi awal terjadinya hal tersebut? Mengapa pada akhirnya gereja bisa “menyerap” praktik-praktik kebudayaan yangdemikian? Memang benar adanya bahwa banyak orang Tionghoa peranakan di Indonesia yang menganut agama Kristen sehingga menerapkan liturgi Kristen pada budaya Tionghoa yang mungkin bertentangan ataupun tidak sesuai dengan nilai-nilai Kekristenan. Kendati demikian, manakah yang lebih dulu hadir?Budaya atau agama?
Kasih Kristus dan Filantropi Kristen pada Kegiatan Sega Mubeng di Pastoran Gereja Santo Antonius Padua Kotabaru Yogyakarta
Authors: Rofi'ah Zulfatur , Rizal Abdullah Muslich Rizal Maulana
Published: April 2024

AbstractThis descriptive qualitative research aimed to determine the activities of sega mubeng at the Saint Anthony of Padua Catholic Church Presbytery, Kotabaru, Yogyakarta, as a form of Christ’s love and Christian philanthropy. Accordingly, this research collected data through interviews, field observations, and documentation. This study concluded that the goodness taught to the love of Christ in the form of loving and caring for one another by distributing rice boxes was realized in sega mubeng. In addition, sega mubeng also stands as the practice of Christian philanthropy in the form of Charity, referring to unconditional love through welfare for the recipients of rice boxes.
AbstrakPenelitian ini bertujuan untuk mengetahui kegiatan sega mubeng di Pastoran Gereja Santo Antonius Padua Kotabaru Yogyakarta sebagai bentuk kasih Kristus dan filantropi Kristen. Metode penelitian yang digunakan ialah kualitatif deskriptif. Teknik pengumpulan data penelitian ini melalui wawancara, observasi lapangan dan dokumentasi. Hasil dari penelitian ini menunjukkan bahwasanya kebaikan-kebaikan yang diajarkan pada kasih Kristus berupa saling mengasihi dan menyayangi dengan cara membagikan nasi bungkus yang terealisasikan dalam kegiatan ini, terutama motif daripada perasaan para relawan ketika membagikan nasi bungkus kepada kelompok sasaran. Selain itu, kegiatan sega mubeng merupakan bentuk filantropi Kristen yang berupa charity yaitu cinta tak bersyarat dengan cara menyejahterakan kelompok sasaran dengan memberikan nasi bungkus kepada mereka.
“Akulah, Ibu Sang Raja!”: Posttraumatic Growth Penyintas Berdaya
Authors: Hauw Andreas
Published: April 2024

AbstractThe argument of this paper is that Bathsheba, in the stories of 2 Samuel 11-12 and 1 Kings 1:1-2:25, when read in narrative criticism emerge as an empowered survivor of sexual violence. The prophet Nathan,who became Bathsheba’s confidant, contributed to Bathsheba regaining her honor that was lost due to David’s rape. From a trauma studies perspective, Bathsheba experienced posttraumatic growth (PTG), whichis the ability to overcome post-traumatic syndrome disorder (PTSD). This paper is useful in illustrating the narrative’s strategic tactics to get out of a helpless situation. The courageous attitude in expressing bitterexperiences, good relationships with the environment, appreciation of life, the opening of new opportunities, and connection with God are factors of Bathsheba’s PTG.
AbstrakArgumentasi tulisan ini adalah Batsyeba dalam kisah 2 Samuel 11-12 dan 1 Raja-raja 1:1-2:25, yang dibaca dalam kritik narasi (narrative criticism), akan tampil sebagai penyintas kekerasan seksual yang berdaya. NabiNatan, yang menjadi lingkungan terdekat Batsyeba, berkontribusi bagi Batsyeba untuk mendapatkan kembali kehormatan yang pernah hilang darinya karena rudapaksa Daud. Dalam kacamata studi trauma, Batsyeba mengalami posttraumatic growth (PTG), yaitu kemampuan mengatasi posttraumatic syndrome disorder (PTSD). Tulisan ini bermanfaat dalam menggambarkan taktik strategis narasi untuk keluar dari situasi tak berdaya. Sikap berani dalam mengungkapkan pengalaman pahit, relasi baik dengan lingkungan, penghargaan terhadap hidup, terbukanya kesempatan baru dan hubungan dengan Allah menjadi faktor PTG Batsyeba.
Ruang Nir-Kata bagi Luka yang Terpendam: Suara Laki-Laki Penyintas Kekerasan Seksual sebagai Sumber Berteologi Trauma
Authors: Sariri Meilina Simon , Rahyuni Daud Pori  , Kevin Daniel Simorangkir
Published: April 2024

AbstractThis paper offers a wordless space as a term for the wounded space for male survivors of sexual violence. Wordless space is offered as a perspective on trauma theology from the perspective of male survivors ofsexual violence. This perspective departs from the data on sexual violence against men, which is quite high but still lacks attention from various parties. The assumption that men are the perpetrators of sexual violence, social constructions of masculinity and certain theological thinking have resulted in male survivors of sexual violence suppressing the voice of their wounds and limiting the space for the voice of their wounds. The thoughts of Annie Rogers, Cathy Caruth, and Shelly Rambo, in relation to trauma, are used to look at the traumatic experiences of male survivors of sexual violence as well as the basis for wordless space as a perspective in trauma theology.
AbstrakTulisan ini menawarkan ruang nir-kata sebagai sebutan bagi ruang luka bagi laki-laki penyintas kekerasan seksual. Ruang nir-kata ditawarkan sebagai perspektif berteologi trauma dari sudut pandang laki-laki penyintas kekerasan seksual. Perspektif ini berangkat dari data kekerasan seksual pada laki-laki berada pada angka yang cukup tinggi namun masih kurang mendapatkan perhatian dari berbagai pihak. Anggapan tentang laki-laki adalah pelaku kekerasan seksual, konstruksi sosial tentang maskulinitas, dan pemikiran teologi tertentu telah mengakibatkan laki-laki penyintas kekerasan seksual memendam suara luka merekadan membatasi ruang bagi suara luka tersebut. Pemikiran dari Annie Rogers, Cathy Caruth, dan Shelly Rambo, dalam kaitannya dengan trauma, dipakai untuk melihat pengalaman traumatis laki-laki penyintas kekerasan seksual sekaligus landasan bagi ruang nir-kata sebagai perspektif dalam berteologi trauma.
Modern radiation-hygienic state of the territories of the Globus-4 and Gorizont-1 peaceful nuclear explosions in the Komi Republic
Authors: Biblin A. M. , Varfolomeeva K. V. , Sednev K. A. , Ivanov S. A. , Repin V. S. , Georgieva A. G.
Published: April 2024

The article presents results of a study of the radiation environment on territories adjacent to the sites of the “Globus-4” and “Gorizont-1” peaceful nuclear explosions in the Komi Republic. Field survey was carried out in July 2021. The work provides an assessment of the radiation situation in terms of the main indicators: ambient dose equivalent rate, the content of anthropogenic radionuclides in soil, tritium in the water of water bodies and drinking water supply sources in the settlements nearest to the sites of the peaceful nuclear explosions. The values of gamma radiation ambient dose equivalent rate in all the surveyed territories are at the level of fluctuations of natural regional radiation background and amounted to 0.03 – 0.07 µSv/h in the territory of peaceful nuclear explosion “Globus-4”, 0.01 – 0.05 µSv/h in the territory of “Gorizont-1”. No contaminated soil areas with anthropogenicradionuclides were detected. Tritium activity concentration in water samples does not exceed 5 Bq/kg, which is typical for global levels of this radionuclide in water bodies. The study has shown that the radiation situation in the territory of peaceful nuclear explosions “Globus-4” and “Gorizont-1” meets the requirements of SanPiN 2.6.1.2819-10 “Ensuring radiation safety of the population living in the areas of (1965 – 1988) nuclear explosions for peaceful aims” and currently poses no threat to public health. A conservative dose estimate of additional anthropogenic exposure of individuals from the population from tritium intake with water from centralised water supply sources was 0.065 µSv/year. Longterm radiation safety of the researched territories requires organisation of radiation monitoring, determination of protected zone boundaries and installation of readable information signs warning about radiation hazard and prohibition of economic activities.
Tendência temporal e distribuição espacial das taxas das vias de parto, segundo características maternas no Brasil, entre 2011 e 2020
Authors: Prates Leticia Furlan de Lima , Da Silva Maria Luiza Melo , Moroskoski Márcia , De Oliveira Natan Nascimento , Silva Marcela de Andrade Pereira , Melo Emiliana Cristina , De Oliveira Rosana Rosseto
Published: April 2024

Objetivo: analisar a tendência temporal e a distribuição espacial das taxas das vias de parto, segundo as características da mãe brasileira. Método: estudo ecológico, de séries temporais, com distribuição espacial das taxas das vias de parto no Brasil, de 2011 a 2020. Os dados foram selecionados no Sistema de Informações sobre Nascidos Vivos. Para a análise de tendência, o modelo de regressão polinomial foi utilizado. Resultados: foram analisados 29.025.461 nascimentos. Desses, 57,22% foram cesáreas e 42,70% partos vaginais. Houve aumento das taxas de cesárea em todas as regiões brasileiras, exceto no Sudeste, onde foi registrado aumento de partos por via vaginal. Entre as mulheres que tiveram parto vaginal, a maioria era adolescente, com baixa escolaridade, e sem companheiro. A distribuição espacial das taxas de cesáreas indicou concentração de estados com índices elevados dessa via de parto especialmente nas regiões Sul, Sudeste e Centro Oeste. Conclusão: a cesariana é a via de parto predominante de nascimentos no Brasil, com tendência constante e variações entre as regiões e estados. Melhora na formação, educação continuada dos profissionais de saúde e orientação de qualidade para as gestantes e a comunidade são imprescindíveis para garantir qualidade na atenção em saúde durante o período perinatal.
Estudo epidemiológico de crianças e adolescentes acometidas por síndrome respiratória aguda grave na pandemia da covid-19
Authors: Vieira Claudia Cristina Augusto Rodrigues , Reis Adriana Teixeira , De Oliveira Larissa Paiva Alves , Ramos Gabriella Filippini Silva , Tavares Rosangela Cunha Machado , De Mendonça Hugo Santos Lemos
Published: April 2024

Objetivo: Descrever o perfil epidemiológico dos vírus respiratórios e as características clínico-epidemiológicas das crianças e adolescentes hospitalizados com comprometimento respiratório agudo no período da pandemia da covid-19. Metodologia: Trata-se de um estudo transversal descritivo. A população do estudo são crianças e adolescentes de 0 a 18 anos hospitalizadas na unidade de terapia intensiva e enfermaria com comprometimento respiratório agudo, que apresente pelo menos 1 sintoma como febre, mesmo que referida, tosse, dor de garganta, dispneia, saturação de O2 < 95% ou desconforto respiratório, diarreia e vômito no período de março de 2020 a dezembro de 2021. Resultados: No período do estudo foram elegíveis 95 indivíduos, com predomínio do sexo masculino (50,5%) com comorbidades (58,2). O sintoma prevalente foi a dispneia (80%). A internação em unidade de terapia intensiva representou 53,6% e a necessidade de suporte ventilatório não invasivo 40%. O uso de oseltamivir representou 54,7% da amostra e o exame de imagem 28,4% evidenciando infiltrado pulmonar, 98,8% evoluíram com desfecho de cura. O vírus prevalente foi o vírus sincicial respiratório RSV.  Conclusão: A importância do conhecimento da epidemiologia atual sobre vírus respiratórios nesta população contribui para uma prática clínica assertiva e direciona o cuidado ao público-alvo em questão, além de contribuir nas medidas de bloqueio e mitigação dos riscos de desfechos desfavoráveis.
Frequência de lesões HPV induzidas em mulheres atendidas no SUS e sua relação com fatores de risco
Authors: Busnardo Daniela Kist , Cervini Ricardo , Centa Ariana , Locatelli Claudriana
Published: April 2024

Objetivo: investigar a frequência de lesões HPV induzidas em mulheres atendidas pelo Sistema Único de Saúde, do município de Caçador - SC, com alteração na colpocitologia oncótica e sua relação com fatores de risco. Métodos: a amostra foi constituída de exames citopatológicos cérvico-vaginais alterados do município, entre 01/08/2018 e 31/07/2019, associada a análise do prontuário médico. Resultados: a maioria das pacientes têm idade superior a 20 anos, têm filhos, usam método contraceptivo hormonal, tiveram início da atividade sexual aos 16,37 ± 2,64 anos, não foram imunizadas contra HPV e não fazem uso de preservativos. Relacionando com o grau de lesão observa-se um número significativo de pacientes acima dos 30 anos, com filhos, que fazem uso de contraceptivo hormonal e são tabagistas com lesões NICII/III ou carcinoma in situ. Conclusão: a amostra analisada apresenta fatores de risco que favorecem o desenvolvimento do CCU mostrando a necessidade de estratégias de política pública.
A disfunção temporomandibular e a idade predizem a qualidade de vida relacionada à saúde oral em homens e mulheres?
Authors: De Oliveira Rogéria Vicentini , De Oliveira Daniel Vicentini , Nascimento Júnior José Roberto , Massuda Ely Mitie
Published: April 2024

Este estudo teve como objetivo verificar se a disfunção temporomandibular (DTM) e a idade predizem a qualidade de vida relacionada à saúde oral (OHRQoL) em homens e mulheres. Trata-se de uma pesquisa quantitativa, analítica, observacional e transversal. A amostra foi escolhida intencionalmente e por conveniência, composta por 407 adultos de ambos os sexos, residentes em diferentes regiões do Brasil. Foi utilizado um questionário sociodemográfico com questões relacionadas a sexo, idade, escolaridade, renda, entre outras; também foram utilizados o Oral Health Impact Profile (OHIP-14) e o Fonseca Anamnesic Questionnaire. Os dados foram analisados ​​pelos testes Kolmogorov-Smirnov, Levene, bootstrapping, t de Student, d de Cohen, correlação de Pearson e análise de regressão múltipla (p<0,05). As mulheres se perceberam como tendo pior OHRQoL e maior prevalência de DTM. O aumento do escore de DTM está associado à piora da OHRQoL, com maior intensidade entre as mulheres. Para as mulheres, a DTM foi um preditor positivo para todos os domínios e para o escore total da OHRQoL, enquanto a idade apresentou predição significativa e positiva apenas nos domínios limitação funcional (β=0,14), incapacidade física (β=0,17) e escore total (β =0,10). Para os homens, a DTM foi um preditor positivo, enquanto a idade não apresentou predição significativa nos domínios e no escore total da OHRQoL. As mulheres se perceberam como tendo pior OHRQoL e maior DTM. Vale ressaltar que a DTM foi um fator interveniente na OHRQoL tanto de homens quanto de mulheres, e a idade pode potencializar essa influência nas mulheres.
Groundwater flow simulation for artificial recharge: a GIS, remote sensing, and MODFLOW integration
Authors: Nawale Sanchita , Mategaonkar Meenal
Published: April 2024

Groundwater (GW) emerges as a sustainable resource to meet water demand, yet current GW reservoirs fall short of projected population needs. Artificial GW recharge, bolstered by Geographical Information System (GIS) and Remote Sensing (RS) technologies, stands out as a pivotal solution. Examining Aurangabad district in Maharashtra, India the study uncovers distinct challenges: Aurangabad faces escalating water demand due to population growth, leading to GW over exploitation. Leveraging hydrogeological parameters, rainfall analysis, and GW availability, the study proposes tailored GW recharge techniques. Utilizing MODFLOW simulation, the study explores diverse recharge rates and existing GW availability, showcasing promising results. Integration of stream augmentation, bladder pillow tank methods, and dug well recharge is examined via GIS and RS techniques. Simulation outcomes project significant GW level increases (11.55–23.70 m) with varying recharge rates, effectively meeting region-specific water demand projections. The findings underscore the imperative of sustainable water management practices and technological advancements in addressing water scarcity crises.
Geniposide Attenuates Oxygen-glucose Deprivation/Recovery-induced Retinal Ganglion Cell Injury via Akt/Nrf-2 Signaling Pathway
Authors: Hu Minghai , Chen Dekun , Wu Xiuyu , Ren Guo-Feng
Published: April 2024

Background:

Glaucoma is an eye disease. Its pathological process involves
retinal ischemia-reperfusion (I/R), which causes irreversible blindness in patients. Geniposide
(Gen), a bioactive iridoid glycoside extracted from the fruit of gardenia, exhibits
many biological effects, such as anti-oxidative stress, anti-inflammation, anti-apoptosis,
anti-endoplasmic reticulum stress, and anti-thrombotic effects. However, its therapeutic
potential for the retinal I/R injury remains unclear. This study investigated the protective
effect of Gen against I/R injury by inhibiting abnormal reactive oxygen species (ROS)
and retinal neuron apoptosis.

background:

Glaucoma is a blinding eye disease, and retinal ischemia -reperfusion (I/R) is an important pathological process of glaucoma. Geniposide (Gen), as an important active natural component from Gardenia jasminoides Ellis fruit, which exerts multiple biological activities.

Methods:

We used oxygen-glucose deprivation/reoxygenation (OGD/R) to induce R28
cells to mimic the pathological process of I/R in glaucoma. We conducted CCK-8 analysis
and TUNEL staining to examine cell proliferation and apoptosis in glaucoma. Western
blotting was used to assay the expressions of apoptosis and Akt/Nrf-2 pathway-related
proteins.

Results:

The production of ROS was detected by using the corresponding kit. Cell viability
decreased, whereas TUNEL staining-positive cells and ROS production increased after
the OGD/R injury. The contents of cleaved caspase-3 and Bax/Bcl-2 increased after
the OGD/R injury. Treatment with 200 μM of Gen effectively improved the cell viability
and suppressed cell apoptosis and ROS production. In addition, Gen could significantly
promote the activation of the Akt/Nrf-2 signaling pathway in R28 cells, which was
blocked by the inhibition of Akt/Nrf-2. We in vivo verified the neuroprotective effect of
Gen by establishing an acute high intraocular pressure (aHIOP) model and obtained similar
results to those of the in vitro experimental results.

Conclusion:

Hence, it can be suggested that Gen provides neuroprotection against the
OGD/R-induced injury of R28 cells by activating the Akt/Nrf-2 signaling pathway,
which is beneficial for the clinical treatment of glaucoma.
1,3,4-Oxadiazole Scaffold in Antidiabetic Drug Discovery: An Overview
Authors: Gupta Ojasvi , Chawla Gita , Pradhan Tathagata
Published: April 2024

:

Diabetes mellitus is one of the biggest challenges for the scientific community in the 21st
century. With the increasing number of cases of diabetes and drug-resistant diabetes, there is an urgent
need to develop new potent molecules capable of combating this cruel disease. Medicinal
chemistry concerns the discovery, development, identification, and interpretation of the mode of
action of biologically active compounds at the molecular level. Oxadiazole-based derivatives have
come up as a potential option for antidiabetic drug research. Oxadiazole is a five-membered heterocyclic
organic compound containing two nitrogen atoms and one oxygen atom in its ring. Oxadiazole
hybrids have shown the ability to improve glucose tolerance, enhance insulin sensitivity, and
reduce fasting blood glucose levels. The mechanisms underlying the antidiabetic effects of oxadiazole
involve the modulation of molecular targets such as peroxisome proliferator-activated receptor
gamma (PPARγ), α-glucosidase, α-amylase and GSK-3β which regulate glucose metabolism and
insulin secretion. The present review article describes the chemical structure and properties of
oxadiazoles and highlights the antidiabetic activity through action on different targets. The SAR for
the oxadiazole hybrids has been discussed in this article, which will pave the way for the design and
development of new 1,3,4-oxadiazole derivatives as promising antidiabetic agents in the future. We
expect that this article will provide comprehensive knowledge and current innovation on oxadiazole
derivatives with antidiabetic potential and will fulfil the needs of the scientific community in designing
and developing efficacious antidiabetic agents.
Revolutionizing Oral Cancer Treatment: Immunotherapeutic Approaches
Authors: Islam Md Moidul , Raikwar Sarjana
Published: April 2024

Background:

Immunotherapy is a promising addition to the cancer treatment arsenal, with
the potential to be an effective adjuvant therapy. In the ever-changing landscape of cancer care, it
appears as a potential fourth pillar, supplementing surgery, chemotherapy, and radiation. The key to
effective immunotherapy is cautious patient selection, which is based on a thorough study of the
unique immune makeup of each patient.

Aim:

This review article aims to provide a comprehensive understanding of the fundamental principles
of tumor immunity and immunotherapy, with a specific focus on oral squamous cell carcinoma.

Methods:

The review involved a thorough investigation of scientific databases and relevant publications,
including studies conducted up to the present date obtained from PubMed, Science Direct, and
Google Scholar Key. The selected studies underwent careful evaluation for methodological rigor and
the significance of their findings.

Results:

Checkpoint inhibitors, targeted monoclonal antibodies, adoptive cell transfer, cancer vaccines,
biomarkers and prediction tools, and cytokine immunotherapy are all promising treatments for
oral cancer.

Conclusion:

In recent decades, there has been a substantial increase in interest and study in cancer
immunotherapy, indicating a turning point in our approach to cancer treatment. While significant
progress has been made, major hurdles remain across a range of cancers.
Sintering Driven Void Formation in PS@WO3 Core-Shell Composites: A Photodegradation Enhancement Strategy
Authors: Yeh Min Yen , You Ruei Ying , Cheng Po Wen , Hwang Shih-Syuan , Hu Gui-Cheng , Chang Shun Hsyung
Published: April 2024

Background:

Polystyrene nanospheres are used as a substrate for the hydrothermal coating
of tungsten trioxide (WO3) to form a core-shell composite of PS@WO3. The core-shell structure
is used for the next sintering step. This produces porous WO3. The focus of this study is on the role
of porous WO3 in enhancing photocatalytic performance.

Methods:

The hydrothermal method was employed for coating, and the surface morphology, as well
as the structural properties of WO3-coated PS spheres, were systematically investigated using SEM
and XRD analyses. Additionally, the sintering process was introduced to enhance the material by
inducing rupture in the PS sphere core, creating voids that significantly increased the material's surface
area.

Results:

The evaluation of the effect of sintering temperature on photodegradation efficiency highlighted
the crucial role of sintering temperature. Un-sintered and 300°C sintered WO3, both having a
hexagonal crystalline structure, exhibited superior degradation efficiencies compared to samples
sintered at higher temperatures (400°C and 500°C). In particular, the 300°C sintered WO3 outperformed
its un-sintered counterpart despite identical crystalline structures. The performance of the
PS@WO3 composite was assessed to determine the enhanced role of porous WO3. The porous WO3
obtained, in particular by the sintering of the core-shell PS@WO3 composites at 300°C, showed a
remarkable improvement in the degradation efficiency. These composite demonstrated over 95%
efficiency within 10 minutes and achieved near complete (100%) degradation for a further 10
minutes, surpassing the performance of pure WO3. It is important to clarify that while the final product
was predominantly WO3 after the sintering process, the inclusion of PS served a critical purpose
in creating voids during sintering. The PS@WO3 composite structure used as a resource for the preparation
of porous WO3, even with a potentially reduced PS composition, has been found to play a
significant role in influencing the surface area of the material, and consequently the photocatalytic
performance.

Conclusion:

The study has highlighted the importance of crystalline structure and sintering conditions
in optimizing the efficiency of photocatalytic materials. The porous WO3 obtained, in particular
by the sintering of the core-shell PS@WO3 composites at 300°C, showed promising potential for
applications under UV and visible LED light irradiation. These results provide valuable insights for
the development of advanced photocatalytic materials with improved performance, highlighting
WO3 as the key contributor to the observed improvements.
Investigating the Mechanism of Banxia Xiexin Decoction in Treating
Gastritis and Diabetes Mellitus through Network Pharmacology and
Molecular Docking Analysis
Authors: Du Yikuan , Chi Xianhong , Chen Qianwen , Xiao Yue , Ma Zhendong , Wang Zhenjie , Guo Zhuoming , Chen Peng , Chen Zilin , Zhang Mengting , Guo Jinyan , Zhou Yuqi , Yang Chun
Published: April 2024

Background:

Banxia Xiexin decoration (BXD), a complex prescription in Traditional Chinese
Medicine (TCM), clinically acts as a treatment for gastritis and diabetes while its mechanism of
treatment remains unknown.

Objection:

This study aimed to explore the common mechanism of BXD in treating gastritis and
diabetes based on network pharmacology and molecular docking technology.

Methods:

The seven Chinese herbal components and drug targets were collected from the Traditional
Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) for gastritis and
diabetes using GeneCards, DisGeNET, Comparative Toxicogenomics Database (CTD), and Online
Mendelian Inheritance in Man (OMIM) databases. Common drug and disease targets were imported
into the STRING data platform for protein-protein interaction (PPI) analysis, and Cytoscape 3.7.2
software for network topology analysis, and core targets were filtered.

Results:

There were 124 components, 249 targets, 449 targets for gastritis, and 4005 targets for diabetes.
After mapping, 83 BXD targets for gastritis and diabetes were obtained, and the targets with
high correlation were STAT 3, JUN, TNF, IL-6, etc. More relevant targets were involved in the cancer
pathway, AGE-RAGE signaling pathway of diabetic complications, fluid shear stress, and atherosclerosis
pathway.

Conclusion:

This study preliminarily reveals that BXD may play a role in the treatment of gastritis
and diabetes mellitus through multi-components, multi-targets, and multi-pathways, and proposes
some potential "component-target-pathway" hypotheses in light of previous reports.