bluuebunny/crossref_metadata_2025 huggingface dataset:
Short-Term Prognostic Value of the Culprit-SYNTAX Score in Patients with Acute Myocardial Infarction
Authors: Peker Tezcan , Boyraz Bedrettin
Published: June 2023

Background: The SYNergy between Percutaneous Coronary Intervention with TAXus and Cardiac Surgery (SYNTAX) score is a scoring system that helps to decide on surgery or percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (MI), and studies are showing the prognostic value of this scoring system in both AMI and coronary artery disease patients undergoing PCI. In acute coronary syndrome (ACS) patients, the infarct-related artery and the complexity of the lesions are also important in terms of mortality and morbidity. Our study aimed to determine the prognostic value of the culprit vessel’s SYNTAX score (cul-SS) in patients presenting with MI. Methods: In our study, 1284 patients presenting with MI were analyzed retrospectively. The SYNTAX scores and cul-SS of the patients were calculated. In-hospital and 30-day deaths and major complications were accepted as primary outcomes. The SYNTAX scores and cul-SS were compared in terms of predicting primary outcomes. Conclusions: Major complications were observed in 36 (2.8%) patients, death in 42 (3.3%) patients, and stent thrombosis in 24 (1.9%) patients. The area under the curves for SYNTAX and cul-SS for predicting primary outcomes is 0.64 and 0.68 (p = 0.026), respectively. Cul-SS was as successful as the SYNTAX score in predicting stent thrombosis and was superior in predicting short-term death and major complications.
Exploring the Diversity of Visceral, Subcutaneous and Perivascular Adipose Tissue in a Vascular Surgery Population
Authors: Ferreira Joana , Afonso Julieta , Carneiro Alexandre Lima , Vila Isabel , Cunha Cristina , Roque Susana , Silva Cristina , Mesquita Amílcar , Cotter Jorge , Correia-Neves Margarida , Mansilha Armando , Longatto-Filho Adhemar , Cunha Pedro
Published: June 2023

The prevalence of obesity has doubled, with a concomitant increase in cardiovascular disease. This study aimed to compare the characteristics of visceral, subcutaneous and peri-aortic adipose tissue determined with computed tomography (CT) scans and to correlate them with cardiovascular risk factors, anthropometric measures and medication. An observational and prospective study was conducted, and 177 subjects were included. Peri-aortic adipose tissue had the highest density, while the subcutaneous adipose tissue had the lowest. The density of subcutaneous adipose tissue differs from the density of visceral (p = 0.00) and peri-aortic adipose tissue (p = 0.00). Smokers/ex-smokers had a lower area (p = 0.00) and density (p = 0.02) of subcutaneous adipose tissue. Multiple linear regression analysis showed that sex was a predictor of subcutaneous adipose tissue area (β = −0.27, t = −3.12, p = 0.00) but smoking habits were not. After controlling for sex, we found that the association between smokers/ex-smokers and area of subcutaneous adipose tissue was lost, but the association with density persisted. Patients with hypertension had a higher visceral adipose tissue area, and this relationship was maintained even after adjusting for gender. Peri-aortic adipose tissue is similar to visceral and distinct from subcutaneous adipose tissue. Cardiovascular risk factors have different influences in distinct adipose compartments.
Hysteroscopic Findings and Operative Treatment: All at Once?
Authors: D’Urso Valentina , Gulino Ferdinando Antonio , Incognito Giosuè Giordano , Cimino Monia , Dilisi Valentina , Di Stefano Alessandra , Gulisano Marianna , Cannone Francesco , Capriglione Stella , Palumbo Marco
Published: June 2023

Hysteroscopy is considered not only a diagnostic instrument but also a therapeutic tool for many uterine pathologies. In the early 1990s, advances in technology and techniques made hysteroscopy less painful and invasive, allowing to increase in the number of gynecological procedures performed in an ambulatory setting without significant patient discomfort and with potentially significant cost savings. This is the so-called “office hysteroscopy” or “see-and-treat hysteroscopy”, whose spread has permitted the decrease of the number of procedures performed in the operating room with the benefit of obviating the need for anesthesia and dilatation of the cervical canal.
Post-Traumatic Headache: A Review of Prevalence, Clinical Features, Risk Factors, and Treatment Strategies
Authors: Mavroudis Ioannis , Ciobica Alin , Luca Alina Costina , Balmus Ioana-Miruna
Published: June 2023

Post-traumatic headache (PTH) is a common and debilitating consequence of mild traumatic brain injury (mTBI) that can occur over one year after the head impact event. Thus, better understanding of the underlying pathophysiology and risk factors could facilitate early identification and management of PTH. There are several factors that could influence the reporting of PTH prevalence, including the definition of concussion and PTH. The main risk factors for PTHs include a history of migraines or headaches, female gender, younger age, greater severity of the head injury, and co-occurring psychological symptoms, such as anxiety and depression. PTH clinical profiles vary based on onset, duration, and severity: tension-type headache, migraine headaches, cervicogenic headache, occipital neuralgia, and new daily persistent headache. Pharmacological treatments often consist of analgesics and non-steroidal anti-inflammatory drugs, tricyclic antidepressants, or antiepileptic medication. Cognitive behavioral therapy, relaxation techniques, biofeedback, and physical therapy could also be used for PTH treatment. Our work highlighted the need for more rigorous studies to better describe the importance of identifying risk factors and patient-centered treatments and to evaluate the effectiveness of the existing treatment options. Clinicians should consider a multidisciplinary approach to managing PTH, including pharmacotherapy, cognitive behavioral therapy, and lifestyle changes.
Management of Adrenal Cortical Adenomas: Assessment of Bone Status in Patients with (Non-Functioning) Adrenal Incidentalomas
Authors: Trandafir Alexandra-Ioana , Stanciu Mihaela , Albu Simona Elena , Stoian Vasile Razvan , Ciofu Irina , Persu Cristian , Nistor Claudiu , Carsote Mara
Published: June 2023

Our aim is to analyse the bone profile in adults with (non-functioning) adrenal incidentalomas (AIs), specifically addressing the impact of autonomous cortisol secretion (ACS). This narrative review, based on a PubMed search from inception to February 2023 (case reports, non-ACS, and other secondary causes of osteoporosis were excluded), included 40 original studies, a total of 3046 patients with female prevalence (female:male ratio of 1921:1125), aged between 20.5 and 95.5 years old. This three decade-based analysis showed that 37 studies provided dual-energy X-ray absorptiometry (DXA) information; another five studies reports results on bone micro-architecture, including trabecular bone score (TBS), spinal deformity index, and high-resolution peripheral quantitative computed tomography; 20 cohorts included data on bone turnover markers (BTMs), while four longitudinal studies followed subjects between 1 and 10.5 years old (surgical versus non-adrenalectomy arms). Post-dexamethasone suppression test (DST) cortisol was inversely associated with bone mineral density (BMD). TBS predicted incidental vertebral fractures (VFx) regardless of BMD, being associated with post-DST cortisol independently of age and BMD. Low BTMs were identified in ACS, but not all studies agreed. An increased prevalence of ACS-related osteoporosis was confirmed in most studies (highest prevalence of 87.5%), as well as of VFx, including in pre-menopause (42.5%), post-menopause (78.6%), and male patients (72.7%) depending on the study, with a 10-fold increased incidental VFx risk up to a 12-fold increased risk after a 2-year follow-up. No specific medication against osteoporosis is indicated in ACS, but adrenalectomy (according to four studies) should be part of the long-term strategy. This bone profile case sample-based study (to our knowledge, one of the largest of its kind) showed that AIs, including the subgroup designated as having ACS, embraces a large panel of osseous complications. The level of evidence remains far from generous; there are still no homogenous results defining ACS and identifying skeletal involvement, which might be a consequence of different investigation clusters underling adrenal and bone assessments over time. However, bone status evaluations and associated therapy decisions remain an essential element of the management of adults with AIs-ACS.
Comparative Investigation of Anti-Inflammatory Effect of Platelet-Rich Fibrin after Mandibular Wisdom Tooth Surgery: A Randomized Controlled Study
Authors: Tanan Karaca Gamze , Duygu Gonca , Er Nilay , Ozgun Eray
Published: June 2023

This study evaluated the anti-inflammatory effect of platelet-rich fibrin (PRF) applied to the extraction socket after impacted mandibular third molar surgery with subjective and objective parameters. Forty-eight patients with impacted wisdom teeth in bilateral and similar positions were included in the study. The control group was formed with the standard surgery and the PRF group was formed with local PRF application in addition to standard procedure (n = 96). The anti-inflammatory activity of PRF on postoperative 2nd and 7th days was evaluated subjectively by clinical parameters and objectively by biochemical parameters. Postoperative 2nd- and 7th-day follow-up data of pain, edema, and trismus in the PRF group were found to be statistically significantly lower. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were found to be statistically significantly lower in the PRF group than the control in the postoperative 2nd-day follow-up period (p < 0.001). There was no statistically significant difference in interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-α) parameters when the PRF group and the control group were compared in both follow-up periods (p > 0.05). The study has demonstrated the effectiveness of locally applied PRF after ITM surgery via clinical parameters and objective data. The quantitative analysis of CRP and ERS can be an effective parameter in determining the amount of inflammation after ITM surgery.
A Modified Single-Armed Suture Technique for Traumatic Cyclodialysis Cleft with Vitreoretinal Injury
Authors: Zhang Xueyong , Wang Nan , Zheng Guoli , Liu Die , Zhang Quyan , Lei Wenbo , Xia Xiaobo , Xiong Siqi
Published: June 2023

Our aim was to assess the therapeutic efficacy of a modified single-arm suture technique on traumatic cyclodialysis cleft with vitreoretinal injury. The procedure involved fixing a detached ciliary body using a single-armed 10-0 polypropylene suture under the assistance of a 29-gauge needle. Patients with a traumatic cyclodialysis cleft combined with an anterior and posterior segment injury who underwent modified internal cyclopexy together with vitreoretinal surgery were enrolled in this study. Ultrasound biomicroscopy (UBM) was used to diagnose and evaluate the cyclodialysis and anterior segment injury. B-scan ultrasonography was performed to assess the condition of the vitreous, retina and choroid. The surgical time and successful rate for repairing the cyclodialysis cleft were recorded. Preoperative and postoperative best-corrected visual acuity (BCVA), and intraocular pressure (IOP) were documented for assessment. The study included 20 eyes. The extent of the cyclodialysis cleft was from 30° to 360°. Besides a traumatic cyclodialysis cleft, the included cases also combined this with vitreous hemorrhages, retinal detachment, macular holes, choroid avulsion, and suprachoroidal hemorrhage. All the clefts were anatomically closed in one surgery. The average surgical time for fixing the cyclodialysis cleft was 2.68 ± 0.54 min/30° cleft. A significant improvement in LogMAR BCVA was observed from 2.94 ± 0.93 preoperatively to 1.81 ± 1.11 at the 6-month follow-up. IOP was elevated from 10.90 ± 6.18 mmHg preoperatively to 14.45 ± 2.35 mmHg at the 6-month follow-up. The modified single-armed suture technique was proved to be an effective method to fix the traumatic cyclodialysis cleft, which could facilitate the use of the procedure to repair chorioretinal disorders. It improved the BCVA and maintained the IOP with less postoperative complications.
Comparison of Grip Strength Measurements by Widely Used Three Dynamometers in Outpatients Aged 60 Years and Over
Authors: Savas Sumru , Kilavuz Asli , Kayhan Koçak Fatma Özge , Cavdar Sibel
Published: June 2023

Grip strength (GS) is widely used in various fields such as sports, rehabilitation, and geriatrics to assess muscle strength, and to diagnose sarcopenia and frailty in older adults. There is a potential for measurement differences among different dynamometers available, and studies comparing GS measurements by variable tools have conflicting results. The two most frequently used dynamometers are the Jamar hydraulic (Jamar) and spring-type hand grip dynamometers, and Jamar has not been compared to Jamar PLUS+ Digital (Jamar+) dynamometer in older adults. So, we aimed to assess GS measurements with the Jamar as the reference standard against Jamar+, and spring-type Takei T.KK. 5401 (Takei) digital dynamometers. One hundred and ten outpatients aged >60 years were included. Inter-instrumental reliability was determined. The differences between dynamometers were evaluated by Bland–Altman plots and measurement error. The measurements with Jamar+, and Takei dynamometers were reliable and valid regarding the Jamar dynamometer. Takei and Jamar+ dynamometers overestimated GS over the Jamar dynamometer. Though the differences in the measured values might be disregarded in clinical practice, individuals defined to have low GS varied by the use of different dynamometers. Grip strength better be measured by the same dynamometer in serial measurements of older individuals.
Fatigue Perception in Adolescents with Obesity and Their Caregivers
Authors: Guerrini Usubini Anna , Bottacchi Michela , Bondesan Adele , Marazzi Nicoletta , Castelnuovo Gianluca , Sartorio Alessandro
Published: June 2023

Although fatigue is a frequently occurring symptom in young patients with obesity, relatively few studies have assessed their perception of fatigue and its impact on their quality of life so far. Comparisons between the reports of fatigue in children/adolescents with obesity and their parents were assessed using the Pediatric Quality of Life Inventory-Multidimensional Fatigue Scale (PedsQL-MFS). One hundred Italian children/adolescents (36 males; 64 females), aged between 11 and 17 (mean age = 15.3; SD = 1.61) with severe obesity [mean Body Mass Index (BMI: kg/m2) = 38; SD = 5.48] and their caregivers were enrolled. Perception of fatigue did not change by sex and rates of obesity in adolescents, while there was a difference (p = 0.040) in parents’ reports of cognitive fatigue between parents of children/adolescents of Group 1 (BMI SDS 2–2.99) and Group 2 (BMI SDS > 3), with a higher perception of fatigue in parents of the less heavy obese children. Significant differences in reports of general fatigue subscale were found between children/adolescents and their parents, being higher in their parents than in the young subjects with obesity (p < 0.001). Significant moderate correlations between all the subscales of PedsQL-MFS for children and parents were found with Pearson’s coefficients ranging from 0.529 to 0.571 (p < 0.001). The perception of fatigue measured with the PedsQL-MFS was comparable between obese children and their parents, thus indicating that this symptom is not hidden by children and is clearly perceived by their parents.
Artificial Neural Networks and the Actiotope Model of Giftedness—Clever Solutions from Complex Environments
Authors: Phillipson Shane N. , Han Cindy Di , Lee Vincent C. S.
Published: June 2023

Since its inception, the Actiotope Model of Giftedness (AMG) has provided researchers with a useful model to explain the development of exceptionality. Rather than a focus on the individual, the model postulates that exceptionality is the outcome of a system that includes complex interactions between an individual’s current level of talent and their internal and external environment. To date, however, the statistical techniques that have been used to investigate the model, including linear regression and structural equation modeling, are unable to fully operationalize the systemic nature of these interactions. In order to fully realize the predictive potential and application of the AMG, we outline the use of artificial neural networks (ANNs) to model the complex interactions and suggest that such networks can provide additional insights into the development of exceptionality. In addition to supporting continued research into the AMG, the use of ANNs has the potential to provide educators with evidence-based strategies to support student learning at both an individual and whole-school level.
Comprehensive Evaluation of Marine Ship Fires Risk Based on Fuzzy Broad Learning System
Authors: Zhang Chuang , Zhang Xiaofan , Liu Songtao , Guo Muzhuang
Published: June 2023

Ship fires exhibit the main characteristics of a high possibility of occurrence, large load, fast spreading, high difficulty in extinguishing, and serious losses. Therefore, once a fire occurs, it will cause huge loss in terms of economic and personnel safety. Firstly, a ship fire risk evaluation indicator system was constructed based on the causes and severity of the fires. Secondly, a comprehensive evaluation method for the fuzzy broad learning system (FBLS) was proposed. The fuzzy system was used to implement feature mapping on the input data, and the extracted fuzzy features were further input into the BLS enhancement layer. A fuzzy broad learning neural network structure was constructed by combining fuzzy features, feature nodes, and enhancement nodes. The method was applied to the field of risk assessment for the first time, and is a reference for subsequent studies. Finally, the risk levels of ship fires were classified and compared with evaluation methods such as fuzzy support vector machine (FSVM) and Fuzzy BP neural network (FBPNN) to demonstrate effectiveness and accuracy. The proposed FBLS method was used to predict actual cases, and the results showed consistency with the level determined by the accident investigation report published by the Maritime Bureau Administration.
Prediction of Added Resistance of Container Ships in Regular Head Waves Using an Artificial Neural Network
Authors: Martić Ivana , Degiuli Nastia , Grlj Carlo Giorgio
Published: June 2023

In this paper, an artificial neural network was used to predict the added resistance coefficient for container ships in regular head waves for various speeds. The data used for training the neural network were gathered based on performed numerical calculations using the Boundary Integral Element Method for various hull forms of container ships. The numerically obtained results were validated against the available experimental data for three benchmark container ships. The data were divided into three classes based on the ship length, and the expressions for the prediction of the added resistance coefficient for each container ship class were provided. The performance and generalization properties of the neural network were evaluated based on the normalized value of the root mean square error. The model enables reliable prediction of the added resistance coefficient within the preliminary design stage of a ship based on the ship characteristics and speed.
Species Diversity of Helvella lacunosa Clade (Pezizales, Ascomycota) in China and Description of Sixteen New Species
Authors: Wang Xin-Cun , Zhuang Wen-Ying , Zhao Rui-Lin
Published: June 2023

Helvella lacunosa and its allies are widely distributed in the Northern Hemisphere and perform important functions in ecosystems. A comprehensive study on 101 collections of Helvella lacunosa, including those deposited in four Chinese fungaria or collected recently from 10 provinces, was conducted based on morphological and molecular characteristics. Phylogenies of “Helvella lacunosa clade” inferred from Hsp90, ITS, LSU, and TEF were reconstructed with 49 lineages recognized, of which 25 lineages occurred in China, and each represented an individual species. Sixteen new species were determined with detailed descriptions and illustrations. Two new Chinese records were reported. Species concepts and their distinctions in macro- and micro-features were discussed.
Unveiling the Morphostructural Plasticity of Zoonotic Sporotrichosis Fungal Strains: Possible Implications for Sporothrix brasiliensis Virulence and Pathogenicity
Authors: Corrêa-Junior Dario , Bastos de Andrade Iara , Alves Vinicius , Avellar-Moura Igor , Brito de Souza Rabello Vanessa , Valdez Alessandro Fernandes , Nimrichter Leonardo , Zancopé-Oliveira Rosely Maria , Ribeiro de Sousa Araújo Glauber , Almeida-Paes Rodrigo , Frases Susana
Published: June 2023

Sporotrichosis is a fungal infection caused by Sporothrix species, with Sporothrix brasiliensis as a prevalent pathogen in Latin America. Despite its clinical importance, the virulence factors of S. brasiliensis and their impact on the pathogenesis of sporotrichosis are still poorly understood. This study evaluated the morphostructural plasticity of S. brasiliensis, a fungus that causes sporotrichosis. Three cell surface characteristics, namely cell surface hydrophobicity, Zeta potential, and conductance, were assessed. Biofilm formation was also analyzed, with measurements taken for biomass, extracellular matrix, and metabolic activity. In addition, other potential and poorly studied characteristics correlated with virulence such as lipid bodies, chitin, and cell size were evaluated. The results revealed that the major phenotsypic features associated with fungal virulence in the studied S. brasiliensis strains were chitin, lipid bodies, and conductance. The dendrogram clustered the strains based on their overall similarity in the production of these factors. Correlation analyses showed that hydrophobicity was strongly linked to the production of biomass and extracellular matrix, while there was a weaker association between Zeta potential and size, and lipid bodies and chitin. This study provides valuable insights into the virulence factors of S. brasiliensis and their potential role in the pathogenesis of sporotrichosis.
Current Cardioprotective Strategies for the Prevention of Radiation-Induced Cardiotoxicity in Left-Sided Breast Cancer Patients
Authors: Nikovia Vasiliki , Chinis Evangelos , Gkantaifi Areti , Marketou Maria , Mazonakis Michalis , Charalampakis Nikolaos , Mavroudis Dimitrios , Orfanidou Kornilia Vasiliki , Varveris Antonios , Antoniadis Chrysostomos , Tolia Maria
Published: June 2023

Background: Breast cancer (BC) is the most common malignancy in females, accounting for the majority of cancer-related deaths worldwide. There is well-established understanding about the effective role of radiotherapy (RT) in BC therapeutic strategies, offering a better local–regional control, prolonged survival, and improved quality of life for patients. However, it has been proven that conventional RT modalities, especially in left-sided BC cases, are unable to avoid the administration of high RT doses to the heart, thus resulting in cardiotoxicity and promoting long-term cardiovascular diseases (CVD). Recent radiotherapeutic techniques, characterized by dosimetric dose restrictions, target volume revision/modifications, an increased awareness of risk factors, and consistent follow-ups, have created an advantageous context for a significant decrease inpost-RT CVD incidence. Aim: This review presents the fundamental role of current cardioprotective strategies in the prevention of cardiotoxic effects in left-BCRT. Material and Methods: A literature search was conducted up to January 2023 using the Cochrane Central Register of Controlled Trials and PubMed Central databases. Our review refers to new radiotherapeutic techniques carried out on patients after BC surgery. Specifically, a dose evaluation of the heart and left anterior descending coronary artery (LADCA) was pointed out for all the included studies, depending on the implemented RT modality, bed positioning, and internal mammary lymph nodes radiation. Results: Several studies reporting improved heart sparing with new RT techniques in BC patients were searched. In addition to the RT modality, which definitely determines the feasibility of achieving lower doses for the organs at risk (OARs), better target coverage, dose conformity and homogeneity, and the patient’s position, characteristics, and anatomy may also affect the evaluated RT dose to the whole heart and its substructures. Conclusions: Modern BC RT techniques seem to enable the administration of lower doses to the OARs without compromising on the target coverage. The analysis of several anatomical parameters and the assessment of cardiac biomarkers potentiate the protective effect of these new irradiation modalities, providing a holistic approach to the radiation-associated risks of cardiac disease for BC patients. Despite technological advances, an inevitable cardiac radiation risk still exists, while adverse cardiac events may be observed even many years after RT. Studies with longer follow-ups are required in order to determine the effectiveness of modern breast RT techniques.
Eco-Efficiency of the Urban Agglomerations: Spatiotemporal Characteristics and Determinations
Authors: Xue Shuting , Wang Chao , Zhang Shibin , Weng Chuyao , Zhang Yuxi
Published: June 2023

Attaining optimal eco-efficiency is of paramount importance in promoting the sustainable and harmonious development of the economy and environment within urban agglomerations. Firstly, this paper utilizes the Super-SBM model with undesirable output to measure the eco-efficiency (EE) of 64 cities in the Beijing–Tianjin–Hebei metropolitan region (BTHMR), the Yangtze River Delta (YRD), the Pearl River Delta (PRD), and the Chengdu–Chongqing Economic Zone (CCEZ) from 2006 to 2019. Secondly, this study puts forth a novel and comprehensive index system aimed at evaluating the urbanization efficiency and sheds light on the spatiotemporal changes in EE and urbanization efficiency. Finally, the STIRPAT model is used to examine the influencing factors of EE and to investigate the correlation between EE and urbanization efficiency. The study found that the overall EE of the four typical urban agglomerations is high, but the trend varies with a decrease of about 12.9% from 2006 to 2019. The mean EE is in the order of CCEZ > PRD > BTHMR > YRD, with mean values of 0.941, 0.909, 0.842, and 0.732, respectively. The level of science and technology and the urbanization efficiency have a significant positive impact on EE, while population, industrial structure, FDI, and greening level have an inhibitory effect on urban eco-efficiency. Based on the results, policy suggestions such as paying attention to regional heterogeneity and giving full play to the government’s macro-regulatory role in shaping the economic and industrial structure are proposed to serve as a guide for the coordinated development of urban agglomerations under the Dual Carbon Target.
Building a Community’s Adaptive Capacity for Post-Mining Plans Based on Important Performance Analysis: Case Study from Indonesia
Authors: Sutrisno Agung Dwi , Chen Yun-Ju , Suryawan I Wayan Koko , Lee Chun-Hung
Published: June 2023

Preparing communities around mines to face the impacts of mine closures is crucial in order to reduce disruptions to their livelihoods. Building the adaptive capacity of these communities will alleviate the burden on governments or mining companies in the future. Unfortunately, adaptive capacity has not yet been integrated into post-mining planning policies. This research aims to develop an adaptive capacity framework for post-mining planning in local communities, focusing on a case study conducted in Indonesia. We developed this framework using the Importance Performance Analysis (IPA) method. The findings indicate that the adaptive capacity framework provides a comprehensive approach to building the capacity to adapt and thrive in post-mining situations. This highlights the importance of continuing to disseminate post-mining plan information, prioritizing access to capital and former mine sites, fostering collaboration, and creating job opportunities. Simultaneously, efforts to increase skills should be reduced, and reallocation of efforts towards community institution building, establishing information centers, and improving community bonds should be prioritized in more important fields and programs. By adopting this framework, communities around mines in Indonesia are expected to enhance their resilience and ability to effectively respond to changing circumstances.
Current Perspectives and Future Directions in Lung Transplantation
Authors: Verzelloni Sef Alessandra , Sef Davorin , Trkulja Vladimir , Marczin Nandor
Published: June 2023

This Special Issue of Life features compelling original research and reviews related to current trends in lung transplantation (LTx) [...]
Histological, Laboratorial, and Clinical Benefits of an Optimized Maintenance Strategy of a Potential Organ Donor—A Rabbit Experimental Model
Authors: Tannous Luana Alves , Westphal Glauco Adrieno , Ioshii Sergio Ossamu , de Lima Alves Guilherme Naves , Pigatto Raul Nishi , Pinto Rafael Luiz , de Carvalho Katherine Athayde Teixeira , Francisco Júlio Cesar , Guarita-Souza Luiz César
Published: June 2023

Introduction: Most transplanted organs are obtained from brain-dead donors. Inflammation results in a higher rate of rejection. Objectives: The objective of this animal model of brain death (BD) was to evaluate the effect of the progressive institution of volume expansion, norepinephrine, and combined hormone therapy on clinical, laboratory, and histological aspects. Methods: Twenty rabbits were divided: A (control), B (induction of BD + infusion of crystalloid), C (BD + infusion of crystalloid and noradrenaline (NA)), and D (BD + infusion of crystalloid + vasopressin + levothyroxine + methylprednisolone + NA). The animals were monitored for four hours with consecutives analysis of vital signs and blood samples. The organs were evaluated by a pathologist. Results: In Group D, we observed fewer number and lesser volume of infusions (p = 0.032/0.014) when compared with groups B and C. Mean arterial pressure levels were higher in group D when compared with group B (p = 0.008). Group D had better glycemic control when compared with group C (p = 0.016). Sodium values were elevated in group B in relation to groups C and D (p = 0.021). In Group D, the organ perfusion was better. Conclusion: The optimized strategy of management of BD animals is associated with better hemodynamic, glycemic, and natremia control, besides reducing early signs of ischemia.
A Virtual You: Reading Kurahashi Yumiko’s Kurai Tabi through Virtuality
Authors: Beckman Jason M.
Published: June 2023

Within literary criticism, the second-person narrative is frequently read within the conventions of the modern realistic novel, tackling the narratee/protagonist as a narratological problem. Such an approach, however, overlooks a core component of what second-person fiction aims to do: that is, draw the reader into the narrative and experience the world of the text firsthand. Seeking instead to theorize the ways in which second-person narratives involve the reader in the text and invite the act of perspective-taking, I turn to virtual reality, which is deeply invested in the cognitive mechanisms through which a sense of presence is produced and in questions of how the mediated experience of virtual reality can influence human thought and behavior. Examining Kurahashi Yumiko’s Kurai Tabi (1961), one of the earliest examples of the literary form in Japanese literature, I consider how the reader can experience presence during moments in the text, and how the text drives the reader’s identification with the “you” who is the target of the narration. Analyzing the second-person narrative as a virtuality provides a new avenue for understanding the reader’s cognitive engagement and experience of second-person fiction.
Determination of Safety-Oriented Pavement-Friction Performance Ratings at Network Level Using a Hybrid Clustering Algorithm
Authors: Bao Jieyi , Jiang Yi , Li Shuo
Published: June 2023

Pavement friction plays a crucial role in ensuring the safety of road networks. Accurately assessing friction levels is vital for effective pavement maintenance and for the development of management strategies employed by state highway agencies. Traditionally, friction evaluations have been conducted on a case-by-case basis, focusing on specific road sections. However, this approach fails to provide a comprehensive assessment of friction conditions across the entire road network. This paper introduces a hybrid clustering algorithm, namely the combination of density-based spatial clustering of applications with noise (DBSCAN) and Gaussian mixture model (GMM), to perform pavement-friction performance ratings across a statewide road network. A large, safety-oriented dataset is first generated based on the attributes possibly contributing to friction-related crashes. One-, two-, and multi-dimensional clustering analyses are performed to rate pavement friction. After using the Chi-square test, six ratings were identified and validated. These ratings are categorized as (0, 20], (20, 25], (25, 35], (35, 50], (50, 70], and (70, ∞). By effectively capturing the hidden, intricate patterns within the integrated, complex dataset and prioritizing friction-related safety attributes, the hybrid clustering algorithm can produce pavement-friction ratings that align effectively with the current practices of the Indiana Department of Transportation (INDOT) in friction management.
Manufacturing Process, Microstructure and Physico-Mechanical Properties of W-Cr Coatings Reinforced by Cr3C2 Phase Produced on Tool Steel through Laser Processing
Authors: Bartkowski Dariusz , Bartkowska Aneta
Published: June 2023

This paper presents study results of laser processing of W-Cr, WCr/Cr3C2 and Cr3C2 pre-coats applied on steel substrate in the form of paste. For this study, production parameters were selected to obtain the greatest possible durability of final coatings. Laser processing was carried out using a diode laser machine with a rated power of 3 kW. The laser beam scanning speed was constant at 3 m/min, but variable laser beam powers were used: 600 W, 900 W and 1200 W. Multiple laser tracks with 60% overlapping were used. After remelting the pre-coat with a steel substrate, new coatings were obtained. Following the experiment, microstructure, microhardness, wear, corrosion resistance and chemical composition were investigated. It was found that it is possible to produce W-Cr/Cr3C2 coatings through laser processing. These coatings do not have the characteristics of a composite coating; however, increasing the reinforcing phase in the pre-coat positively affects the wear resistance and microhardness. The addition of a reinforcing phase was found to lead to a microhardness of about 750–890 HV01 for 25% and 75% Cr3C2, respectively, in comparison to coating without Cr3C2. The wear resistance of coatings reinforced by chromium carbide improved more than twofold in reference to the W-Cr coating.
Research on Forming Limit Stress Diagram of Advanced High Strength Dual-Phase Steel Sheets
Authors: Cui Hongjian , Li Di , Fu Qiutao , Lu Zipeng , Xu Jiachuan , Jiang Ning
Published: June 2023

The Forming Limit Stress Diagram (FLSD) can accurately describe the forming process of high-strength steel. However, obtaining FLSD is relatively difficult. In order to predict fracture in advanced high-strength dual-phase (DP) steels, limit maximum and limit minimum principal strains of sheet were obtained through multiple sets of test and simulation. Two material parameters, strength coefficient K and hardening exponent n are introduced into the FLSD function which is established by the strain-stress transformation function. The function shows that the k-value determines the value of the maximum principal stress, while the n-value affects the curvature of the curve. Verification of correctness by testing and simulation to within 10% accuracy. This paper explores a new approach to FLSD research based on material properties, which can expand the application scope of FLSD.
Experimental Study on the Physicochemical Properties of Asphalt Modified by Different Anti-Stripping Agents and Their Moisture Susceptibility with Aggregates
Authors: Lu Ziyu , Chen Anqi , Wu Shaopeng , Li Yuanyuan , Zou Yingxue , Zhu Yunsheng , Wang Kaifeng
Published: June 2023

Erosion and the stripping effect of moisture on asphalt mixtures is one of the main reasons for the shortened service life of asphalt pavements. The common mean of preventing asphalt pavements from being damaged by moisture is adding anti-stripping agents (ASAs) to asphalt mixtures. However, the effect regularity and mechanism of anti-stripping agents on the physicochemical properties of asphalt is not exactly defined. This study compared the physical properties of ASA-modified asphalt (AMAs) to determine the optimal dosage and investigated the rheological and adhesion properties. Based on the roller bottle method and water immersion method, the moisture susceptibility of AMAs with three particle sizes was investigated. The results showed that the modification of asphalt using anti-stripping agents was a physical modification. At the optimum dosage of anti-stripping agents (0.3%), the basic physical properties of AMA1 were the most desirable. ASA2 increased the resistance of asphalt for deformation at high temperature by 46%, and AMA3 had the best low-temperature performance. ASAs enhanced the dispersed and polar components in the asphalt binder, improving the adhesion energy of asphalt. AMA3 had the strongest adhesion to the aggregate, with an increase in adhesion work by 2.8 times and a 45% of increase in ER value. This was attributed to ASA3 containing with a large number of metal cations and polar functional groups. It was shown that ASAs provided the most improvement in the anti-stripping performance of asphalt mixtures with 9.5–13.2 mm particles. The amide ASA, phosphate ASA and aliphatic amine ASA improved the water damage resistance of asphalt by 65%, 45% and 78%, respectively. This study can help engineers realize the effects of different types of ASAs on the physicochemical properties of asphalt and select the most suitable type of ASAs according to the service requirements.
Preparation and Micromechanics of Red Sandstone–Phosphogypsum–Cement Composite Cementitious Materials
Authors: Kong Chuiyuan , Zhou Bin , Guo Rongxin , Yan Feng , Wang Rui , Tang Changxi
Published: June 2023

Based on the physical and chemical properties of red sandstone (RS), RS is used to produce composite cementitious materials. The flowability, mechanical strength, and micromechanics of a red sandstone–cement binary cementitious material (RS-OPC) were investigated as functions of the amount of RS replacing the cement (OPC). Additionally, the feasibility of producing red sandstone–phosphogypsum–cement composite materials (RS-PG-OPC) using the phosphogypsum (PG)- enhanced volcanic ash activity of RS was investigated. The products of hydration and microstructures of RS-OPC and RS-PG-OPC were analyzed by XRD, FTIR, TG-DTG, and SEM. RS enhanced the flowability of RS-OPC relative to the unmodified cement slurry but lowered its mechanical strength, according to the experiments. When the quantity of OPC replaced was greater than 25%, the compressive strength after 28 days was substantially reduced, with a maximum reduction of 78.8% (RS-60). The microscopic mechanism of RS-OPC suggested that the active SiO2 in the RS can react with Ca(OH)2 to produce C-S-H but can only utilize small quantities of Ca(OH)2, confirming the low volcanic ash activity of RS. RS was responsible for dilution and filling. The incorporation of 5% PG into RS-PG-OPC slowed the hydration process compared with RS-OPC without PG but also increased the flowability and aided in the later development of the mechanical strength. This was primarily because the addition of PG provided the system with sufficient Ca2+ and SO42− to react with [Al(OH)6]3− to form ettringite (AFt), therefore accelerating the dissolution of Al3+ in RS to generate more AFt and C-(A)-S-H gels. To some extent, this excites the volcanic ash of RS. Therefore, if there is an abundance of waste RS in the region and a lack of other auxiliary cementitious materials, a sufficient quantity of PG and a finely powdered waste RS component can be used to replace cementitious materials prepared with OPC to reduce the mining of raw OPC materials.
Effect of Local Laser Treatment on the Strengthening of Thin-Walled Structures Fabricated from Non-Alloy Steel
Authors: Kapustynskyi Oleksandr , Višniakov Nikolaj
Published: June 2023

This paper describes the development of new metal-processing technologies that enable the control and improvement of the microstructure and properties of metals. This study investigates the impact of one such technology, laser treatment, on the surface of a thin sheet of non-alloy structural steel. This research aims to address a crucial challenge in expanding the industrial applications of thin-sheet steel products by developing a laser processing technology to create structural strengthening ribs, which can significantly influence the overall strength and stiffness of metal components.
Design of Strain-Hardening Natural TRM Composites: Current Challenges and Future Research Paths
Authors: Illampas Rogiros , Oliveira Daniel V. , Lourenço Paulo B.
Published: June 2023

This paper discusses the challenges in using natural fibers for the development of textile-reinforced mortar (TRM) composites with pseudo-strain-hardening and multiple cracking behavior. The particular characteristics of natural vegetal fibers are analyzed with reference to data from the literature. It is concluded that the efficient use of these fibers as composite reinforcement requires the development of treatment or impregnation protocols for overcoming durability issues, eliminating crimping effects in tensile response and imparting dimensional stability. Relevant experimental research on the synthesis and performance of natural TRMs is reviewed, showing that the fabrication of such systems is, at present, largely based on empirical rather than engineering design. In order to set a framework regarding the properties that the constituents of natural TRM must meet, a comparative analysis is performed against inorganic matrix composites comprising synthetic, mineral and metallic reinforcement. This highlights the need for selecting matrix materials compatible with natural fibers in terms of stiffness and strength. Furthermore, a rational methodology for the theoretical design of natural TRM composites is proposed. First-order analysis tools based on rule-of-mixtures and fracture mechanics concepts are considered. Based on the findings of this study, paths for future research are discussed.
Topological Avenue for Efficient Decontamination of Large Volumes of Fluids via UVC Irradiation of Packed Metamaterials
Authors: Enaki Nicolae A. , Munteanu Ion , Paslari Tatiana , Turcan Marina , Starodub Elena , Bazgan Sergiu , Podoleanu Diana , Ristoscu Carmen , Anghel Sinziana , Badiceanu Maria , Mihailescu Ion N.
Published: June 2023

Nowadays, metamaterials application enjoys notoriety in fluid decontamination and pathogen annihilation, which are frequently present in polluted fluids (e.g., water, blood, blood plasma, air or other gases). The depollution effect is largely enhanced by UVC irradiation. The novelty of this contribution comes from the significant increase by packing of the total surface of metamaterials in contact with contaminated fluids. Packed metamaterial samples are subjected to UVC irradiation, with expected advantages for implant sterilization and long-term prevention of nosocomial infections over large clinical areas. The novel aspect of the investigation consists of a combination of big and small elements of the metamaterial to optimize the above effects connected with fluids and irradiation. The big elements allow the radiation to penetrate deep inside the fluid, and the small elements optimally disperse this radiation toward deeper regions of the metamaterial. A packing scheme of smaller, in-between large metamaterial spheres and fibres is proposed for promoting enhanced depollution against pathogen agents. It is demonstrated that the total surface of metamaterials in contact with contaminated fluids/surface is significantly increased as a result of packing. This opens, in our opinion, new auspicious perspectives in the construction of novel equipment with high sensibility in the detection and decontamination of microorganisms.
Hybrid Additive and Subtractive Manufacturing Method Using Pulsed Arc Plasma
Authors: Duan Xiaoming , Cui Ruirui , Yang Haiou , Yang Xiaodong
Published: June 2023

In this study, a novel hybrid additive and subtractive manufacturing method using pulsed arc plasma (PAP-HASM) was developed to better integrate additive and subtractive processes. The PAP-HASM process is based on the flexible application of pulsed arc plasma. In this PAP-HASM method, wire arc additive manufacturing using pulsed arc plasma (PAP-WAAM) and dry electrical discharge machining (EDM) milling were used as additive and subtractive techniques, respectively; both are thermal machining processes based on pulsed arc plasma, and both are dry machining techniques requiring no working fluids. The PAP-HASM can be easily realized by only changing the pulsed power supply and tool electrodes. A key technological challenge is that the recast layer on the part surface after dry EDM milling may have a detrimental effect on the component fabricated by PAP-HASM. Here, the hybrid manufacturing method developed in this study was validated with commonly used 316L stainless steel. Preliminary experimental results showed that the PAP-HASM specimens exhibited excellent tensile properties, with an ultimate tensile strength of 539 ± 8 MPa and elongation of 46 ± 4%, which were comparable to the PAP-WAAM specimens. The recast layer on the surface after dry EDM milling has no significant detrimental effect on the mechanical properties of the parts fabricated by PAP-HASM. In addition, compared with components fabricated by PAP-WAAM, those fabricated by PAP-HASM showed significantly better surface roughness.
Perspectives on Thermochemical Recycling of End-of-Life Plastic Wastes to Alternative Fuels
Authors: Nanda Sonil , Sarker Tumpa R. , Kang Kang , Li Dongbing , Dalai Ajay K.
Published: June 2023

Due to its resistance to natural degradation and decomposition, plastic debris perseveres in the environment for centuries. As a lucrative material for packing industries and consumer products, plastics have become one of the major components of municipal solid waste today. The recycling of plastics is becoming difficult due to a lack of resource recovery facilities and a lack of efficient technologies to separate plastics from mixed solid waste streams. This has made oceans the hotspot for the dispersion and accumulation of plastic residues beyond landfills. This article reviews the sources, geographical occurrence, characteristics and recyclability of different types of plastic waste. This article presents a comprehensive summary of promising thermochemical technologies, such as pyrolysis, liquefaction and gasification, for the conversion of single-use plastic wastes to clean fuels. The operating principles, drivers and barriers for plastic-to-fuel technologies via pyrolysis (non-catalytic, catalytic, microwave and plasma), as well as liquefaction and gasification, are thoroughly discussed. Thermochemical co-processing of plastics with other organic waste biomass to produce high-quality fuel and energy products is also elaborated upon. Through this state-of-the-art review, it is suggested that, by investing in the research and development of thermochemical recycling technologies, one of the most pragmatic issues today, i.e., plastics waste management, can be sustainably addressed with a greater worldwide impact.