bluuebunny/crossref_metadata_2025 huggingface dataset:
PENENTUAN GEOMETRI DAN KARAKTERISTIK IKATAN SENYAWA KOMPLEKS NI(II)-DIBUTILDITIOKARBAMAT DENGAN METODE DENSITY FUNCTIONAL THEORY
Authors: Pongajow Nicolin Tirza , Juliandri Juliandri , Hastiawan Iwan
Published: April 2018

AbstrakDensity Functional Theory (DFT) merupakan salah satu metode komputasi yang digunakan untuk perhitungan kimia. Metode ini dapat menyelesaian persamaan Schrödinger secara sederhana karena didasarkan pada densitas elektron. Dalam penelitian ini ditentukan geometri dan karaktersitik ikatan dari senyawa kompleks Ni(II)-dibutilditiokarbamat menggunakan metode DFT dengan fungsi B3LYP, B3PW91 dan BLYP. Basis set yang akan digunakan adalah LANL2DZ dan perangkat lunak Gaussian 03W. Hasil optimasi geometri Ni(II)-dibutilditiokarbamat menunjukkan bentuk struktur yang sama dengan Ni(II)-dietilditiokarbamat sebagai data pembanding, yaitu persegi planar. Keterisian elektron pada ikatan Ni – S adalah 1,8873 elektron, yang merupakan 20,24 % elektron dari Ni dan 79,76 % dari S. Bentuk geometri persergi planar dibuktikan dengan hasil analisis NBO yang menunjukkan hibridisasi Ni(II)-dibutilditiokarbamat adalah d1,05sp2.05. Kata kunci: DFT, dibutilditiokarbamat, geometri, karakteristik ikatan, senyawa kompleks. AbstractDensity Functional Theory (DFT) is one of computational method that used for chemical calculation. This method simplifies the complex solution of Schrödinger equation using electron density. In this study the geometry and bond characterization of Ni(II)-dibutyldithiocarbamat complex compound was determined. The computational method used was Density Functional Theory as applied in B3LYP, B3PW91 and BLYP functions. All calculations were performed at LANL2DZ level of basis set as implemented Gaussian 03W. The theoretical result on geometry showed a similar structure to square-planar Ni(II)-dietyldithiocarbamate. The electronic occupation of Ni–S molecular orbital was 1.8873 electron, which was 20.24% electron contribution from Ni and 79.76% from S. Square-planar geometry proved by NBO analysis result that the hybridization of Ni(II)-dibutyldithiocarbamate was d1,05sp2.05. Keywords: DFT, dibutyldithiocarbamate, geometry, bond characterization, complexes compound.
PROFIL PASIEN KO-INFEKSI TUBERCULOSE-HIV DI RSUD DOK II JAYAPURA Tuberculosis-HIV Co-infection Profile in DOK II Hospital Jayapura
Authors: Sianturi Elfride Irawati , Rusnaeni Rusnaeni
Published: April 2018

AbstrakPapua adalah daerah yang memiliki angka prevalensi HIV-AIDS tertinggi di Indonesia. Infeksi TB adalah infeksi oportunistik terbanyak yang menyerang pasien HIV-AIDS.  Tujuan penelitian ini adalah untuk mengetahui profil pasien koinfeksi TB-HIV yang mendapatkan pengobatan obat anti tuberculosis (OAT) di klinik VCT RSUD Dok II Jayapura selama periode Januari 2011 hingga September 2012. Penelitian ini merupakan penelitian retrospektif deskriptif. Data diambil dari rekam medik, kartu TB 01 dan hasil mikrobiologis pasien koinfeksi TB-HIV yang mengambil OAT di  klinik VCT RSUD Dok II Jayapura. Hasil penelitian menunjukkan bahwa 35 dari 124 pasien adalah pasien default yang mengalami efek samping obat dan tidak memiliki Pengawas Minum Obat (PMO). Efek samping obat TB menjadi kendala selama pengobatan sehingga peranan PMO yang berasal dari keluarga inti mampu membantu pasien menyelesaikan pengobatan TB tersebut. Kata kunci: AIDS, pengawas minum obat (PMO), rifampisin, tuberculosis, AbstractPapua shows the highest prevalency rate of HIV-AIDS in Indonesia and almost 60% people who live with HIV develop tuberculosis (TB), hence TB is the most common opportunistic infection in HIV patients. This study was aimed to know and to describe the profile of TB-HIV co-infection patients among TB patients according to clinical symptoms and the side effects of FDC (Fixed Dose Combination) drugs. Methods used was descriptive study taken from medical record of 124  TB-HIV co-infection patients in Dok II Jayapura hospital, Papua during January  2011 – September 2012. Results showed that 35 of 124 patients indicated side effect of antituberculosis risk default when they did not undergo drug monitoring therapy. The patients should be controlled by his/her family to help them through all the side effects of antituberculose drugs to complete the treatment. Keywords: AIDS, drug monitoring therapy, rifampicin, tuberculosis
PERFORMA DOMBA LOKAL BETINA DEWASA PADA BERBAGAI VARIASI LAMANYA PENGGEMBALAAN DI DAERAH IRIGASI RENTANG KABUPATEN MAJALENGKA
Authors: Somanjaya Rachmat , Heriyadi Denie , Hernaman Iman
Published: April 2018

Penelitian mengenai “Performa Domba Lokal Betina Dewasa pada Berbagai Variasi Lamanya Penggembalaan di Daerah Irigasi Rentang Kabupaten Majalengka”, telah dilaksanakan sejak Tanggal 25 Maret sampai 30 Juli 2015. Penelitian ini bertujuan untuk mengukur lamanya waktu penggembalaan optimum terhadap performa domba lokal betina dewasa yang digembalakan di Daerah Irigasi Rentang Kecamatan Jatitujuh Kabupaten Majalengka. Sampel Domba Lokal betina dewasa dalam penelitian ini adalah sebanyak 62 ekor yang tersebar pada variasi penggembalaan <4 jam 19 ekor, 4-6 jam 21 ekor, dan >6 jam 22 ekor. Metode penelitian yang digunakan adalah survey dan observasi. Data yang diperoleh dianalisis secara deskriptif, untuk mengetahui perbedaan rata-rata performa domba diuji dengan Analisys of Varian (Anova one way) serta dilanjutkan dengan uji jarak berganda Duncan. Hasil penelitian menunjukan bahwa penggembalaan >6 jam merupakan lama penggembalaan yang optimum, dibuktikan dengan performa induk secara keseluruhan lebih baik dari lama penggembalaan <4 jam dan 4 – 6 jam. Kata Kunci      :           Domba Lokal, Lama Penggembalaan, Performa Produksi, dan Potensi Hijauan
Effective anti-adhesives of uropathogenic Escherichia coli
Authors: Ribić Rosana , Meštrović Tomislav , Neuberg Marijana , Kozina Goran
Published: April 2018

Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most common infectious diseases in humans. Due to their frequent occurrence in the community and nosocomial settings, as well as the development of resistance to the commonly prescribed antimicrobial agents, an enormous financial burden is placed on healthcare systems around the world. Therefore, novel approaches to the prevention and treatment of UTIs are needed. Although UPEC may harbour a plethora of virulence factors, type I fimbriae and P pili are two of the most studied adhesive organelles, since the attachment to host cells in the urinary tract is a crucial step towards infection. Design of receptor analogues that competitively bind to UPEC surface adhesins placed at the top of pili organelles led to the development of anti-adhesive drugs that are increasingly recognized as important and promising alternatives to antibiotic treatment of UTIs.
Anti-inflammatory potential of Lactobacillus plantarum LS/07 in acute colitis in rats
Authors: Emília Hijová , Izabela Bertková , Jana Štofilová , Ladislav Strojný , Anna Chmelárová , Alojz Bomba
Published: April 2018

To evaluate the efficiency of the probiotic strain Lactobacillus plantarum LS/07 in dextran sulphate sodium (DSS) induced acute colitis selected biochemical (activity of β-glucuronidase), microbiological (counts of lactobacilli and coliforms), and immunological (IL-6, IL-8, IL-13, NF-κB, MPO) parameters were assessed. Sprague-Dawley rats were divided into groups: Control, Acute colitis, and Probiotic. Acute colitis was induced using 5% DSS in drinking water for 7d. DSS induced an inflammatory process in the colonic tissue, increased the activity of β-glucuronidase (p<0.001), increased the counts of coliform bacteria and decreased lactobacilli counts (p<0.05), and activated the production of the measured parameters (NF-κB, MPO, IL-6, IL-8) except of IL-13. Lactobacillus plantarum LS/07 in the diet alleviated the DSS induced inflammatory process by inhibiting the production of IL-6, IL-8, the activities of NF-κB and MPO, and stimulated the production of IL-13. The probiotic reduced the activity of β-glucuronidase (p<0.05), increased lactobacilli counts and decreased coliform bacteria. These results indicate that dietary intake of Lactobacillus plantarum LS/07 suppressed the expression of markers playing an important role in the inflammatory process. We conclude that the anti-inflammatory properties of Lactobacillus plantarum LS/07 makes its suitable for the prevention or treatment of colitis.
Association of the A Allele of the TNF-Alpha-308 G/A Gene Polymorphism with Radiographic Progression in Rheumatoid Arthritis
Authors: Stojanović Sonja , Stamenković Bojana , Nedović Jovan , Jevtović-Stoimenov Tatjana , Pavlović Dušica
Published: April 2018

To examine whether the presence of the rare A allele of the TNF-Alpha-308 G/A gene polymorphism is associated with erosive arthritis and rapid radiological progression of the disease.

The examined group included 131 patients with early RA. Using the PCR-RFLP method, the TNF-Alpha-308 G/A gene polymorphism was determined for all patients. In relation to the presence of the A allele of the examined polymorphism, the patients were divided into two subgroups: subgroup A (G/A and A/A genotypes) and subgroup G (G/G genotype). Based on the presence of the destructive changes in joints found in the initial radiographs, the findings were classified as erosive and non-erosive RA. Radiological progression was assessed on the basis of the annual change in the Larsen score – LS (0-200).

Group A comprised 62 (47.33%) patients, while group G comprised 69 (52.67%) patients. The presence of cysts and erosions in subgroups A and G was compared before the start of the methotrexate therapy. It was determined that erosions (erosive RA) were statistically significantly more frequent in group A (83.87% of patients) in comparison with group G (44.93% of patients), p < 0,001. Group A patients had a higher value of the Larsen score in relation to the group G both before and after methotrexate was administered for a year (before therapy, LS in group A: 48.58 ± 20.54; in group G 20.73 ± 12.31; p < 0.01; after MTX therapy, LS in group A: 58.32 ± 22.25; in group G 25.35 ± 14.57; p < 0.001). The average value of the annual LS change in group A was statistically significantly greater than the change in group G patients (9.98 ± 4.95 to 5.23 ± 2.72) (p < 0.05).

The presence of the A allele of the TNF-Alpha-308 G/A gene polymorphism is associated with the occurrence of early erosive joint changes and more rapid radiological progression of the disease.
Spectroscopic Characterization of Cobalt (II) Complexes with Reduced Low-Molar Dextran Derivatives
Authors: Mitić Žarko , Nikolić Goran M. , Cakić Milorad , Mitić Sanja , Nikolić Goran S. , Najman Stevo
Published: April 2018

The formation of Co(II) ion complexes with reduced low-molar dextran (RLMD, Mw 5000 g/mol) was studied at the pH range from 7.0 to 13.5. The cobalt content in synthesized Co(II)-RLMD complexes was ~3–12% (AAS) and it generally increases with pH. Co(II)-RLMD complexes were characterized by UV-Vis spectrophotometry and FTIR spectroscopy. UV-Vis data for synthesized complexes indicate tetragonally distorted Oh coordination of Co(II) ions with O atoms from ligand. The presence of IR bands at 765 cm−1 and 910 cm−1 in Co(II)-RLMD complexes indicates the existence of α-(1→6)O-glycosidic bonds. The similarities in the γ(C–H) range of the IR spectra indicate that there is no difference in the conformation of the glucopyranose units in RLMD and Co(II)-RLMD complexes. The occurrence of water molecules in Co(II)-RLMD complexes was confirmed by FTIR spectroscopy of deuterated samples.
Problems with the Administration of Antipsychotic Drugs in Depot Formulations in the Treatment of Schizophrenia
Authors: Ranković Anica , Janković Slobodan
Published: April 2018

The aim of this study was to investigate problems with the administration of antipsychotic long-acting injections (LAIs) in patients with schizophrenia. Besides many benefits, long-acting injections have been associated with a number of complications at the site of the injection.

The qualitative study included four medical workers and five patients who had been treated with fluphenazine, haloperidol, risperidone given in the form of a long-acting depot injection. The data were collected by direct observation, analysis of the history of the disease and used semi-structured interview.

Interviews completed by patients, psychiatrists and nurses were analyzed and condensed into nine key categories: Competence and training of the medical workers, Sites and technique, Registration of complications, Care of patients and privacy, Availability and evidence, Duration and frequency of treatment, Burden for the patients, The choice of formulation therapy, and Sense of stigma.

Monitoring of side-effects of LAIs was not extensive and doctors did not write adverse effects. The nurses who administered the injections were competent. Not enough attention is paid to the choice of the needle diameter and the patient was not given a choice to decide on the sites of the administraton of injection. Three out of five patients did not feel any changes at the injection site, but another patient had severe pain, redness, and induration.

The exchange of information, a possibility of choosing the site of administration, and monitoring of the effects of treatment are all positive strategies that doctors and nurses can use to help patients in the compliance to the treatment with antipsychotic long-acting injections.
Comparative Enantioseparation of Amlodipine by HPLC and Capillary Electrophoresis
Authors: Cârje Anca Gabriela , Balint Alina , Muntean Daniela-Lucia , Hancu Gabriel , Ion Valentin , Imre Silvia
Published: April 2018

Objective: The purpose of this study was to separate the enantiomers of amlodipine by High Performance Liquid Chromatography (HPLC) using ovomucoid (OVM) as chiral selector, respectively by Capillary Electrophoresis (CE) using cyclodextrines and to evaluate the analytical performance of the both proposed methods.

Material and methods: HPLC enantioseparation of amlodipine was performed on an HPLC Agilent Technologies 1100 series using as chiral stationary phase an Ultron ES OVM, 150x4.6 mm column with ovomucoid as chiral selector. The stereoselective CE analysis of amlodipine was achieved on Agilent Technologies 7100 CE using uncoated fused-silica capillaries 48 cm x 50 mm and different type of cyclodextrins as chiral selectors.

Results: A mobile phase consisting of 80% Na2HPO4 10 mM at a pH level of 5.0 and 20% ACN, isocratic elution at a flow of 1 ml/min turned to be the optimal experimental conditions for HPLC analysis (R=5.51; α=1.71) with retention times shorter than 10 minutes for the two isomers, tR (S-AML) = 4.63 (min); tR (R-AML) = 5.54 (min). The migration times for amlodipine enantiomers were tm (S-AML) = 8.15 (min) and tm (R-AML)= 8.45 (min) and the optimum CE conditions have proven to be a buffer solution containing 25 mM H3PO4 at pH 3.0 and 20 mM α-CD as chiral selector and a capillary temperature set at 15°C (R=1.51; α=1.03).

Conclusion: The analytical performances of the chromatographic method using OVM as chiral selector are superior to the electrophoretic analysis method but the CE method is more economical and may represent an alternative to the HPLC chromatographic separation.
Mediators of Inflammation as a Link Between Diabetes Mellitus and Periodontal Breakdown
Authors: Monea Adriana , Eremie Lia Yero , Bukhari Csilla , Beresescu Gabriela , Biris Carmen
Published: April 2018

Our objective was to investigate immunological changes that occur in saliva of subjects with type 2 diabetes mellitus (T2DM) without signs of periodontal disease and to establish if salivary inflammatory cytokines are a possible link between diabetes mellitus and periodontal breakdown.

Material and methods. Twenty T2DM subjects with no periodontal disease and twenty healthy controls were registered for the present study. TNF-α and IL-6 level from saliva and serum were measured. Periodontal tissue samples were histologically examined.

Results: TNF-α and IL-6 levels were higher in T2DM subjects compared to controls, with an extremely significant difference in saliva (p<0.001). Significant inflammation, affecting both epithelial and connective tissues was present in periodontal biopsies.

Conclusions: The subjects showed an increased TNF-α and IL-6 levels, both in serum and -mostly in -saliva of diabetics without signs of periodontal disease, confirming the hypothesis of immunological implication, as a correlation between periodontal disease incidence and diabetes mellitus. Histologic alterations, suggesting a local inflammatory state, were present in periodontal tissue of diabetics, confirming the above hypothesis. The study reveals that saliva analysis is a quite efficient method in testing the periodontal breakdown progression in the subjects with T2DM.
The Kinetics of the Oxidation of Lysine by μ-Peroxo-Bridged Binuclear Cobalt (III) Complex of Succinimide in Aqueous Hydrochloric Acid Medium
Authors: Adetoro Ahmed , Idris Suleiman O. , Onu Ameh D. , Okibe Friday G.
Published: April 2018

Kinetics of oxidation of Lysine (Lys) and mechanisms by μ-peroxo bis[bis(ethylenediamine)succinimidato-dicobalt(III)]dinitratedihydrate; [LCo(μ-O2)CoL](NO3)2.2H2O (L = suc(en)2), hereafter the complex, was investigated at 420 nm wavelength of maximum absorption of the complex under the conditions hydrogen ions concentration = 1.8 × 10−2 mol dm−3, temperature = 24 ± 1 °C, [LCo(μ-O2)CoL2+] = 1.4 × 10−4 mol dm−3 and ionic strength = 0.5 mol dm−3. First order in [LCo(μ-O2)CoL2+] and [Lys] were obtained but inverse first order in [H+]. The proposed overall rate equation is as shown:

Rate
=
(

k
1

k
2

+

K
1

k
3

k
4

1

[

H
+

]

)
[
LCo
(
μ

O
2

)

CoL

2
+

]
[
Lys
]

$$Rate = ({{k_1 } \over {k_2 }} + {{K_1 k_3 } \over {k_4 }}{1 \over {[H^ + ]}})[LCo(\mu O_2 )CoL^{2 + } ][Lys]$$

Rate of the reaction decreases when hydrogen ions concentration increase and exhibited converse effect with increase in concentration of ionic strength from 0.1 – 1.3 mol dm−3. Added cations and anions affected the reaction rate and the Michaelis-Menten plot passed through the origin indicating no absence of intermediate complex in the electron transfer processes. Putting all the results obtained together, the most probable reaction mechanism is in favour of outer-sphere and an appropriate rate law is established using steady state approximation.
Allelopathic Effect of Dodder on Different Varieties of Lucerne and Bird’s Foot-Trefoil
Authors: Valcheva Ekaterina , Popov Vladislav , Zorovski Plamen , Golubinova Irena , Marinov-Serafimov Plamen , Velcheva Iliana , Petrova Slaveya
Published: April 2018

The aim of this study was to evaluate the allelopathic effect of cold aqueous extracts, both fresh and dry biomass of dodder (Cuscuta epithymum L.) on lucerne (Medicago sativa L.) and bird’s foot-trefoil (Lotus corniculatus L.). Four different varieties of lucerne “Pleven 6”, “Dara”, “Roly”, “Multifoliolate”) and bird’s foot-trefoil (“Gran San Gabriele”, “Leo”, “Local population 1”, “Local population 2”) were studied in order to find some varieties with allelopathic tolerance. Ex-situ experiment was carried out as follows: 100 seeds of each variety were put in Petri dishes between filter paper, both cold extracts of parasitic weed biomass were pipetted at a ratio of 1:20 as against the seed mass and then were placed in a thermostat-operated device at a temperature of 22 ± 2°С. Distilled water was used as a control. Percentage inhibition, Index of tolerance and Index of plant development were calculated for assessment of the allelopathic effect of dodder on the early seedling growth, biomass synthesis and initial development of experimental varieties. As a whole, dry weed biomass was found as more toxic for the tested plants than the fresh one. Medicago sativa var. multifoliolate and Lotus corniculatus var. Local population 1 and Local population 2 showed a significant tolerance to the allelopathic influence of Cuscuta epithymum in all studied concentrations of aqueous extract of fresh weed biomass (25, 50 and 100 g l−1) and medium tolerance to aqueous extract of dry weed biomass (concentrations of 25 and 50 g l−1).
The Impact of Organic Agriculture on Biodiversity Conservation and Milk Quality for Traditional Cheese Production
Authors: Popović-Vranješ Anka , Paskaš Snežana , Becskei Zsolt , Jevtić Marija , Krstović Saša
Published: April 2018

Organic farming represents agricultural practice that could contribute to the preservation of biological diversity and breeding of cows with the most desired milk quality attributes. Milk composition could vary widely according to genetic diversity of the animals and different feeding systems. These are related to higher dry matter content, fat, protein and a more favorable ratio of the saturated/unsaturated fatty acids, which is important in traditional cheese production. Standard chemical analyzes were performed and this paper shows the differences in the chemical properties and the fatty acid profile of milk, depending on the different breeds and breeding methods of animals. Simmental milk (indoors) was most abundant in dry matter and fat (13.01 and 4.30%, respectively) while protein and casein level was the highest in the Busha milk (3.67 and 2.63%, respectively). Holstein Friesian milk (organic) possessed a more constant composition and, together with Busha appropriate hygienic quality of milk (low level of somatic cells and total bacteria count). Also, milk from Holstein Friesian cows (organic) was disposed with better nutritional quality and more desirable fatty acid profile (SFA (63.40%), MUFA (30.79%) and PUFA (5.72 %)). On the other hand, Holstein Friesian (conventional) milk contained SFA (67.45%), MUFA (29.27%) and PUFA (3.28%) while Simmental (indoors) higher values of SFA (71.21%) and less MUFA (25.39%) and PUFA (3.40%). There are various ways to preserve biodiversity and the application of organic production standards in the traditional cheese production contributes to obtaining safer, quality products which are more recognizable on the market.
Green Barley as an Ingredient in Pasta: Antioxidant Activity and Sensory Characteristics Evaluation
Authors: Ivanišová Eva , Košec Martin , Brindza Ján , Grygorieva Olga , Tokár Marián
Published: April 2018

The aims of the present study was to determine antioxidant activity, sensory properties as well as total polyphenol, flavonoid and chlorophyll content of raw and cooked pasta enriched by 1%, 3% and 5% addition of green barley powder. Results of antioxidant activity showed that increase of green barley addition increase antioxidant activity of pasta. The values in raw pasta obtained by DPPH ranged from 1.17 (control) to 1.81 (5% addition) mg TEAC/g DM, after cooking values ranged from 0.82 (control) to 1.59 (5% addition) mg TEAC/g DM. Similar tendency was signed by molybdenum reducing antioxidant power method. In enriched pasta was also found higher content of total polyphenol (0.19 in control raw sample and 1.81 mg GAE/g DM in pasta with 5 % of green barley addition; values of cooked pasta ranged from 0.10 in control sample to 0.73 mg GAE/g DM in pasta with 5 % of green barley addition) as well as total flavonoid content (results of raw pasta were from 0.00 in control sample to 0.41 mg QE/g DM in pasta with 5% of green barley addition; values of cooked pasta were from 0.00 in control sample to 0.29 mg QE/g DM in variant with 5% green barley). Green barley also enriched pasta for chlorophyll with the best results in 5% addition. From prepared variants of enriched pasta the best overall acceptability was sign in 3% of green barley addition. Pastas enriched with plant-derived bioactive compounds such as green barley may confer health benefits to consumers.
Improvements of doubled haploid production protocol for white cabbage (Brassica oleracea var. capitata L.)
Authors: Pilih Katarina Rudolf , Potokar Urška Karolina , Bohanec Borut
Published: April 2018

Protocols leading to the development of doubled haploid (DH) lines by microspore culture are widely used in white cabbage (Brassica oleracea var. capitata L.), but efficiency varies according to the cultivar and induction procedure. Forty different genotypes consisting of F1 cultivars and their crosses with responsive doubled haploid lines were tested to evaluate the androgenic response. In total, 20,032 embryos were produced. On average, the haploid induction response of F1 cultivars was 7.0 embryos/Petri dish, but the average of these hybrids crossed to responsive DH lines was 26.6 embryos/Petri dish. In seven reciprocal crosses, a difference was observed in just one, meaning that the maternal effect probably has a minor influence on haploid embryogenesis in cabbage. Addition of 0.02% activated charcoal (AC) to the induction media increased embryo formation in several low-responsive genotypes, but its effect on embryo formation of high-responsive genotypes was predominantly negative, although larger embryos were formed on media containing AC than without AC. Further development into plantlets was tested by two procedures. Formed embryos were either transferred directly to regeneration medium or treated with abscisic acid and desiccated for 4 weeks. Regrowth and further development reached on average 15.5 and 57.6%, for the first and second procedures, respectively. Plantlets developed by direct transfer often exhibited abnormal development or hyperhydricity, unlike the desiccated embryos. Spontaneous diploidisation of embryos reached 42.5% in total and was not affected by AC added to the induction media.
Dilated Cardiomiopathy - Anatomic-Clinical Study
Authors: Ovidiu Tica , Anca Tica Otilia , Larisa Rosan , Madalina Vidican , Elena Rosca , Vlad Pantea , Ioana Ignat Romanul , Anca Sandor-Huniadi , Mircea Sandor , Cosmin Vesa , Katalin Babes , Mircea-Ioachim Popescu
Published: April 2018

Introduction. Dilated cardiomyopathy (DCM) is characterized by global cardiac dilation associated with left ventricular (LV) systolic dysfunction without valvar substrate or ischemic heart disease. Diagnosis of idiopathic DCM can only be sustained after excluding other nongenetic causes.

Methods. This study was performed on a cohort of 256 patients who died in Emergency County Hospital of Oradea and had diagnosis of DCM; the study was performed on a period of 2 years, from January 2014 until the end of December 2015. These patients were differentiated according to social criteria, background, department of admission, number of autopsies and co-morbidities.

Results and Discussion. Diagnosis of DCM was more common in male patients up to the age of 70; after this age the tendency is towards equalization. In patients aged 61-80 years, DCM played a major role in tanatogenesis. Existing clinical trials have shown that patients with idiopathic DCM have a lower mortality than patients with cardiac ischemic disease.

Conclusions. Despite the possibility of diagnosis with increased sensitivity and the large number of therapeutic options, multicentre studies and registries are needed to improve the life expectancy of these patients.
Mist-Netting of Migrating Bee-Eaters Positively Influences Honey Bee Colony Performance
Authors: Łangowska Aleksandra , Yosef Reuven , Skórka Piotr , Tryjanowski Piotr
Published: April 2018

Bee-eaters (Meropidae) are considered agricultural pests and their presence provokes conflicts with beekeepers and farmers who rely on the pollination services of honey bees. This problem is often deal with through the mass killing of the birds, even though the quantitative evidence on the impact of bee-eaters on honey bee colonies is scarce. The current paper reports the performance of honey bee colonies protected with mist nets from migrating flocks of European bee-eaters Merops apiaster in Israel. In the study the weight gains of bee hives surrounded by mist nets were 6.44 times higher than that of unprotected hives (26.4 kg vs. 4.1 kg). The results confirmed that bee-eaters locally pose a problem to apiaries and potentially to the crops that require pollination. Mist- netting appeared to be an effective mitigation method for alleviating conflicts between beekeepers and bee-eaters. However, the study also showed that bees were able to differentiate between their main predator and other avian species trapped in mist nets and stung only bee-eaters. Moreover, the bees were targeting the most vulnerable body parts of birds which resulted in some bird fatalities. Therefore, due to accidental mortal- ity of birds, mist-netting is recommended only on the migratory routes in cases when bee hives cannot be moved to other areas.
Spatial Rack Drives Pitch Configurations: Essence and Content
Authors: Abadjieva Emilia , Abadjiev Valentin , Naganawa Akihiro
Published: April 2018

The practical realization of all types of mechanical motions converters is preceded by solving the task of their kinematic synthesis. In this way, the determination of the optimal values of the constant geometrical parameters of the chosen structure of the created mechanical system is achieved. The searched result is a guarantee of the preliminary defined kinematic characteristics of the synthesized transmission and in the first place, to guarantee the law of motions transformation. The kinematic synthesis of mechanical transmissions is based on adequate mathematical modelling of the process of motions transformation and on the object, realizing this transformation. Basic primitives of the mathematical models for synthesis upon a pitch contact point are geometric and kinematic pitch configurations. Their dimensions and mutual position in space are the input parameters for the processes of design and elaboration of the synthesized mechanical device. The study presented here is a brief review of the theory of pitch configurations. It is an independent scientific branch of the spatial gearing theory (theory of hyperboloid gears). On this basis, the essence and content of the corresponding primitives, applicable to the synthesis of spatial rack drives, are defined.
Experimental Characterization of the Energy Absorption of Functionally Graded Foam Filled Tubes Under Axial Crushing Loads
Authors: Ebrahimi Saeed , Vahdatazad Nader , Liaghat Gholamhossein
Published: April 2018

This paper deals with the energy absorption characterization of functionally graded foam (FGF) filled tubes under axial crushing loads by experimental method. The FGF tubes are filled axially by gradient layers of polyurethane foams with different densities. The mechanical properties of the polyurethane foams are firstly obtained from axial compressive tests. Then, the quasi-static compressive tests are carried out for empty tubes, uniform foam filled tubes and FGF filled tubes. Before to present the experimental test results, a nonlinear FEM simulation of the FGF filled tube is carried out in ABAQUS software to gain more insight into the crush deformation patterns, as well as the energy absorption capability of the FGF filled tube. A good agreement between the experimental and simulation results is observed. Finally, the results of experimental test show that an FGF filled tube has excellent energy absorption capacity compared to the ordinary uniform foam-filled tube with the same weight.
Evolution of the dicalcium phosphate-dihydrate (DCPD) coating created by large amplitude sinusoidal voltammetry (LASV) on corrosion resistance of the ZW3 magnesium alloy in chloride containing environment
Authors: Kajánek D. , Hadzima B. , Pastorek F. , Jacková M. Neslušan
Published: April 2018

The contribution is focused on the preparation of coating based on the dicalcium phosphate-dihydrate (DCPD) on the surface of ZW3 magnesium alloy. For the preparation of the coating a cathodic electrodeposition technique called Large Amplitude Sinusoidal Voltammetry (LASV) was used. The DCPD layer was prepared at the temperature of 22 ± 2 °C in electrolyte composed of 0.1M Ca(NO3).4H2O, 0.06 M NH4H2PO4 and H2O2. Electrochemical characteristics were evaluated by electrochemical impedance spectroscopy (EIS) in 0.1M NaCl solution. The obtained data in form of Nyquist plots were analysed by the equivalent circuit method. It is clear from the measured values of polarization resistance Rp that dicalcium phosphate-dihydrate (DCPD) layer prepared by LASV electro-deposition technique improved corrosion resistance of ZW3 alloy in the chosen environment.
Visibility and perception analysis of city monuments: The case of Bratislava city centre (Slovakia)
Authors: Oťaheľ Ján , Ira Vladimír , Hlavatá Zuzana , Pazúr Róbert
Published: April 2018

City monuments attract tourists, especially at places with efficient viewpoints. The conditions of visibility of eight historical monuments in the city of Bratislava were evaluated using GIS on a 3D landscape, employing the criteria of distance, impressiveness, size and the number of visible monuments. The visual quality of 15 selected viewpoints was verified by surveying more than 300 respondents about their views of the monuments from similar locations. These approaches allow us to assess the conformity of visual quality analysis conducted in objective and subjective ways. The most attractive viewpoints ranked by observers were remote from the historic town and provided views of several monuments, as well as a comprehensive panoramic view of the centre of Bratislava. The approaches to assessing visual quality analysis presented in this study represent a comprehensive way of defining and verifying which places are the best for effective sightseeing of a city’s monuments.
Correction of Navigational Information Supplied to Biomimetic Autonomous Underwater Vehicle
Authors: Praczyk Tomasz
Published: April 2018

In order to autonomously transfer from one point of the environment to the other, Autonomous Underwater Vehicles (AUV) need a navigational system. While navigating underwater the vehicles usually use a dead reckoning method which calculates vehicle movement on the basis of the information about velocity (sometimes also acceleration) and course (heading) provided by on-board devicesl ike Doppler Velocity Logs and Fibre Optical Gyroscopes. Due to inaccuracies of the devices and the influence of environmental forces, the position generated by the dead reckoning navigational system (DRNS) is not free from errors, moreover the errors grow exponentially in time. The problem becomes even more serious when we deal with small AUVs which do not have any speedometer on board and whose course measurement device is inaccurate. To improve indications of the DRNS the vehicle can emerge onto the surface from time to time, record its GPS position, and measure position error which can be further used to estimate environmental influence and inaccuracies caused by mechanisms of the vehicle. This paper reports simulation tests which were performed to determine the most effective method for correction of DRNS designed for a real Biomimetic AUV.
The Effect of Numerical 2D and 3D Fem Element Modelling on Strain and Stress Distributions at Laser Weld Notches in Steel Sandwich Type Panels
Authors: Niklas Karol , Kozak Janusz
Published: April 2018

Like other means of transport, merchant ships face the problem of increasing requirements concerning the environment protection, which, among other issues, implies the reduction of fuel consumption by the ship. Here, the conventional approach which consists in making use of higher strength steels to decrease the mass of the ship hull can be complemented by the use of new steel structures of sandwich panel type. However, the lack of knowledge and experience concerning, among other issues, fatigue strength assessment of thin-walled sandwich structures makes their use limited. Untypical welds imply the need for individual approach to the fatigue analysis. The article presents the effect of numerical FEM modelling with the aid of two-dimensional (2D) and three-dimensional (3D) elements on the results of strain and stress distributions in the areas of toe and root notches of the analysed laser weld. The presented results of computer simulation reveal that modelling of strain and stress states in 2D (instead of full 3D) affects only the results in close vicinity of the notch, and the observed differences rapidly disappear at a distance of 0.05 mm from the bottom of the notch. The obtained results confirm the possibility of use of numerically effective 2D strain and stress state models for analysing the fatigue strength of laser weld according to local approach.
Phenolic Compounds in Wetland Macrophytes
Authors: Březinová T. Dvořáková , Vymazal J.
Published: April 2018

Phenolics are the most widely distributed class of plant secondary metabolites and higher plants are able to produce several thousand different phenolic compounds. It has been reported that phenolics are more resistant to decomposition due to the negative impact on the microorganisms involved. Therefore, it may be hypothesized that the higher content of phenolics in plant tissue may cause slower decomposition rates and potentially higher carbon sequestration in the soil. The primary goal of this study was to evaluate and compare the content of phenolics in seven common macrophytes in the Czech Republic. Aboveground biomass was sampled in June 2016 at seven different localities and phenolics concentrations determined by spectrophotometric methods according to the Folin-Cioacalteau method ranged from 9.02 to 28.39 g kg−1 dry biomass weight (DW). Several plants were also harvested in August, October and December in order to follow a seasonal pattern. According to the results it seems that surveyed macrophytes vary widely in phenolics concentrations in relation to sampled site, harvesting time, plant species, and plant parts as well.
Organo-Sulphur Garlic Compounds Influence Viability of Mammalian Cells: A Review
Authors: Chmelíková E. , Němeček D. , Dvořáková M. , Heroutová I. , Sedmíková M.
Published: April 2018

Garlic is still in the centre of interest for its therapeutic effects. Currently, attention is focused on physiological effects of organo-sulphur garlic compounds, as alliin, allicin, diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS), and S-allyl cysteine (SAC), particularly on their antioxidant and anticancerogenic effects. SAC has been studied for its ability to decrease the production of reactive oxygen species by modulation of the cell glutathione level together with antioxidative enzyme activity, and by improvement of mitochondrial functions. The main mechanism of DAS, DADS, and DATS is the induction of the internal apoptotic pathway. Garlic compounds have the ability to interfere with the signalling pathways of small gaseous signalling molecules known as gasotransmitters – nitric oxide, hydrogen sulfide, and carbon monoxide. The review presents the effect of garlic compounds on cellular oxidative stress, intrinsic apoptotic and gasotransmitter pathways and compares their effects on tumour and normal mammalian cells.
Ecotoxicity of Wastewater from Medical Facilities: A Review
Authors: Cidlinová A. , Wittlingerová Z. , Zimová M. , Chrobáková T. , Petruželková A.
Published: April 2018

Wastewater from medical facilities contains a wide range of chemicals (in particular pharmaceuticals, disinfectants, heavy metals, contrast media, and radionuclides) and pathogens, therefore it constitutes a risk to the environment and human health. Many micropollutants are not efficiently eliminated during wastewater treatment and contaminate both surface water and groundwater. As we lack information about the long-term effects of low concentrations of micropollutants in the aquatic environment, it is not possible to rule out their adverse effects on aquatic organisms and human health. It is, therefore, necessary to focus on the evaluation of chronic toxicity in particular when assessing the environmental and health risks and to develop standards for the regulation of hazardous substances in wastewater from medical facilities on the basis of collected data. Wastewater from medical facilities is a complex mixture of many compounds that may have synergetic, antagonistic or additive effects on organisms. To evaluate the influence of a wide range of pollutants contained in the effluents from medical facilities on aquatic ecosystems, it is necessary to determine their ecotoxicity.
Analytical Model for Passing Sight Distance Design Criteria of Two-Lane Roads in Sri Lanka
Authors: Mampearachchi W. K. , Masakorala S. R.
Published: April 2018

For a safe overtaking manoeuvre on two-lane highways, drivers need a sufficient sight distance along the roadway, but it depends on the traffic environment. To provide an adequate Passing Sight Distance (PSD), a number of models have been proposed since the initial model introduced by American Association of State Highways and Transport Officials (AASHTO) in 1954. It is a current design practice in Sri Lanka as well, however, not validated for local traffic conditions. This paper will present an alternative PSD model and an evaluation of AASHTO model for national highway design. Experiment was based on GPS data collection. In conclusion, PSD demand was satisfied by AASHTO PSD under mix traffic conditions, but not the safety concerns for speeds greater than 80 km/h, while alternative model successful for all speeds.
HUBUNGAN ANTARA INTELEGENSI KEMAMPUAN MENYIMAK, DAN KEMAMPUAN MEMBACA, DENGAN PRESTASI BELAJAR (STUDI PADA SISWA SMAN DI BANDUNG)
Authors: Adiwiria Pien Supinah
Published: April 2018

Studi ini bertujuan, untuk mengidentifikasi pengaruh intelegensi terhadap kemampuan menyimak dan kemampuan membaca, dan pengaruh intelegensi, kemampuan membaca, dan kemampuan menyimak terhadap prestasi belajar. Studi ini menggunakan sampel sebanyak 112 siswa SMA di kota Bandungf. Studi ini menemukan pengaruh intelegensi terhadap kemampuan menyimak dan kemampuan membaca. Hasil studi ini juga mengindikasikan pengaruh kemampuan membaca terhadap prestasi belajar serta pengaruh kemampuan menyimak terhadap prestasi belajar, juga mengidentifikasi pengaruh gabungan antara intelegensi, kemampuan menyimak, dan kemampuan membaca terhadap prestasi belajar. Studi ini menemukan suatu model sebab akibat dari hubungan intelegensi, kemampuan membaca, dan kemampuan menyimak terhadap prestasi belajar.
PERANAN FOTO DALAM MENINGKATKAN KEMAMPUAN MAHASISWA CALON GURU FISIKA DALAM MEMBUAT MEDIA PEMBELAJARAN FISIKA SEKOLAH MENENGAH YANG KONTEKSTUAL
Authors: Indrawati Indrawati
Published: April 2018

Penelitian ini membahas tentang peranan foto dalamÂ menlngkatkan kemampuan mahasiswa calon guru fisika sekolah menengah dalam membuat media pembelajaran fisika yangÂ kontekstual. Masalah penelitian adalah apakah foto yang memuat gambar kejadian riil tentang hasil aplikasi fisika, peristiwa alam,Â dan sejenisnya dapat difungsikan untuk meningkatkan kemampuanÂ mahasiswa calon guru fisika dalam membuat media pembelajaranÂ Fisika sekolah menengah yang kontekstual? Penelitlan iniÂ menggunakan penelitian tindakan kelas. Setting penelitian adalahÂ pada perkuliahan Media Pembelajaran Fisika di Program Studi Pendidikan Fisika Jurusan PM/PA FKJP Universitas Jember semesterÂ genap tahun 2004/2005. Subyek penelitian adalah mahasiswa yangÂ menempuh mata kuliah Media Pembelajaran saat ltu di program studi yang sama. Teknik pengumpulan data adalah observasi dan alatÂ pengumpulan data berupa catatan lapangan dan daftar cek. DataÂ penelitian dianalisis dengan statistik deskriptif dan dideskripsikanÂ secara kualitatif. Hasil penelitian menunjukkan bahwa Joto dapatÂ digunakan untuk meningkat kan kemampuan mahasiswa dalam membuat media pembelajaran fislka yang kontekstual. PeningkatanÂ kemampuan tersebut berturut-turut untuk aspek kualitas isi dan tujuan, kualitas pembelajaran, dan kualitas teknik ketiga-tiganyaÂ termasuk pada kategori tinggi (baik).
HUBUNGAN KEMAMPUAN PENALARAN DALAM MATEMATIKA DAN MOTIVASI BERPRESTASI TERHADAP PRESTASI BELAJAR MATEMATIKA
Authors: Sappaile Baso Intang
Published: April 2018

Penelitian ini bertujuan untuk mengetahui hubunganÂ kemampuan penalaran dalam matematika dan mativasi berprestasiÂ terhadap prestasi belajar matematika. Masalah dalam penelitian iniÂ adalah apakah kemampuan penalaran dalam matematika danÂ motivasi berprestasi mempunyai hubungan dengan prestasi belajarÂ matematika? Populasi penelitian adalah semua peserta didik kelas I SMU Swasta Kata Makassar. Metade pengambilan sampel yangÂ digunakan adalah stratified cluster random sampling. Sekolah terpilihÂ sebagai sampel adalah SMU Frater Makassar dan SMU Amana Gappa Makassar. Instrumen yang digunakan adalah tes prestasi belajarÂ matematika, tes kemampuan penalaran dalam matematika dan angketÂ motivasi berprestasi. Data yang diperoleh dianalisis dengan memakaiÂ analisis deskriptif dan analisis korelasi. Kesimpulan yang diperoleh adalah (1) kemampuan penalaran dalam matematika mempunyaihubungan positif dengan prestasi belajar matematika, (2) motivasiÂ berprestasi mempunyai hubungan positif dengan prestasi belajarÂ matematika, dan (3) kemampuan penalaran dalam matematika danÂ motivasi berprestasi secara bersama-sama mempunyai hubungan yangÂ signifikan dengan prestasi belajar matematika, dengan koefisienÂ determinasi sebesar 41%.Â
DESAIN DAN PENGEMBANGAN PERANGKAT LUNAK (SOFTWARE) PEMBELAJARAN MATEMATIKA BERBASIS MULTIMEDIA
Authors: Kariadinata Rahayu
Published: April 2018

Perangkat lunak (software) pembelajaran matematika dapatÂ diartikan sebagai bahan ajar matematika yang berbasis teknologiÂ komputer. Penggunaan bahan ajar matematika berbasis komputerÂ sangat memungkinkan untuk mengembangkan kemampuan berpikir.Â Hal ini dikarenakan komputer memiliki kelebihan, diantaranyaÂ komputer memberi fasilitas bagi pengguna untuk mengulang bila Â diperlukan. Salah satu bentuk teknologi komputer yang saat iniÂ banyak digunakan dalam bidang pendidikan, adalah multimedia.Â Elemen-elemen yang terdapat dalam multimedia seperti gambar, grafik,Â warna, animasi, dan video dapat mengoptimalkan peran indera dalamÂ menerima informasi ke dalam sistem memori. Dalam merancang perangkat lunak (software) pembelajaran matematika berbasis mulÂ­timedia terdapat beberapa prinsip yang perlu diperhatikanÂ diantaranya, a) sajian materi harus sesuai dengan kompetensi dasar,Â b) penyajian harus menarik minat siswa, sistematis, mengikuti teoriÂ­-teori belajar, menggunakan bahasa yang tepat, dan memperhatikanÂ tingkat kematangan siswa, c) harus dilengkapi navigasi dan petunjukÂ penggunaannya, dan d) kualitas fisik perangkat lunak harus baik,Â sedangkan pada tahap pengembangan bahan ajar menggunakanÂ model CADMAETD, yaitu concept (konsep), analysis (analisis), deÂ­sign (desain), material collecting (pengumpulan bahan), assembly (pembuatan), evaluation (evaluasi), testing (ujicoba), dan distribuÂ­tion (distribusi).
KARAKTERISTIK DARI PROSES KEPENDIDIKAN YANG BERMAKNA BAGI REVITALISASI PENDIDIKAN MORAL DALAM MENGHADAPI TANTANGAN ZAMAN
Authors: Rijanto Tri
Published: April 2018

Perbuatan korupsi yang dilakukan seseorang ataupunÂ sekelompok orang menunjukkan rendahnya moral bahkan hilangnyaÂ moral individu dan moral bangsa. Ironisnya, korupsi itu terjadi di sekolah, sebagai pusat pembudayaan nilai-nilai moral anak bangsa.Â Rendahnya moral individu dan bangsa menunjukkan gagalnyaÂ pendidikan moral di sekolah. Bangsa yang korup dan moralÂ masyarakatnya rendah akan sulit dalam menghadapi tantanganÂ zaman, yaitu tantangan-tantangan yang lahir dari persoalanÂ­Â persoalan yang dihadapi suatu masyarakat atau suatu bangsa dalamÂ kurun waktu tertentu. Oleh karena itu, diperlukan prosesÂ kependidikan yang bermakna bagi revitalisasi pendidikan moral dalam menghadapi tantangan zaman.