bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatial Targeting of Soil Loss Using RUSLE in GIS: the case of Asokore Mampong Municipality, Ghana
Authors: Dumedah Gift , Kyeremanteng Evans , Dari Ema
Published: May 2019

Soil erosion is a serious environmental problem that is associated with societal impacts including flooding, poor water quality, and loss of plant nutrient leading to low agricultural productivity. Soil erosion wears away the top soil and is controlled by the interaction between several factors including rainfall, steepness of slope, length of slope, vegetation cover, and land management practices. This study developed Geographic Information System (GIS) graphical model based on the Revised Universal Soil Loss Equation (RUSLE), to calculate soil loss in the Asokore Mampong Municipality of the Ashanti region, Ghana. The estimated soil loss was examined the spatial patterns of soil loss and intensity per areas, as an important method for proper planning of management measures. The graphical model was developed using the popular open source GIS software, QGIS, ensuring the availability of the model, automation for any specific area, and its execution to the general public. Data sources used include Digital Elevation Model (DEM) derived from ASTER (Advanced Spaceborne Thermal Emission and Reflection Radiometer), soil properties data obtained from the Global Soil Grids, land cover data from the Global Land Cover by National Mapping Organization (GLCNMO), NDVI (normalized difference vegetation index) data from MODIS (MOD13Q1, 16 Day), and rainfall data from GPCC version 7 (Global Precipitation Climatology Centre). Our results show high levels of soil loss (in tons per hectare per year) in the Municipality, with the capability to spatially target mitigation measures leading to cost effective environmental management.
Water Catchment Zone Mapping for Watershed Management in Gesing Sub-Watershed, Purworejo
Authors: Wicaksono Arief , Pertiwi Shandra S , P Ade Febri Sandhini , Widayani Prima
Published: May 2019

Water is a very important resource involved in almost all life processes on earth, especially for human life. The rapid growth of water consumption with a decrease in the quantity and quality of water sources certainly creates problems of water scarcity or even flooding, which already occurs in some areas of Indonesia. In the last decades, some areas in Purworejo District, Indonesia have experienced floods, landslides, and droughts. This condition indicates that there has been a water quantity problem in the watershed in Purworejo. This study tends to focus on water resource management in terms of management planning. The purpose of this research is to create a water catchment zone map with the integration of remote sensing methods and geographic information systems. Identification of potential water catchment considers several parameters, such as soil permeability, rainfall, soil surface type, slope, and groundwater level. The results map consists of five classes of water catchment zone in the Gesing Sub-watershed. The higher classes were found in the upper watershed and the center of the watershed, especially in the valley section of the river. The lower classes, such as in the center of the watershed were considered as suitable areas to protect the water quality. With the mapping of water catchment zone, it is expected that the government can make appropriate policies related to water resources management of each sub-watershed so that in the end the water supply problem-especially in terms of quantity-can be managed and controlled effectively.
Синтез и противосудорожная активность N-замещенных 4-амино-3-нитрокумаринов
Authors: Мокров Григорий Владимирович , Савельев Владимир Леонидович , Воронина Татьяна Александровна , Литвинова Светлана Александровна , Ковалев Иван Георгиевич , Неробкова Любовь Николаевна , Дмитриенко Артем Олегович , Гудашева Татьяна Александровна , Середенин Сергей Борисович
Published: May 2019

Представлены данные о синтезе и противосудорожной активности новых соединений, относящихся к производным кумаринов. Среди изученных соединений наиболее выраженной противосудорожной активностью обладали N-(3-нитрокумарин-4-ил)-4-аминомасляная кислота (1а) в дозах 60 и 80 мг/кг (в тесте МЭШ) и метиловый эфир N-(3,6-динитрокумарин-4-ил)-4-аминомасляной кислоты (1е) в дозах 20 и 40 мг/кг (в тесте антагонизма с коразолом). Полученные результаты свидетельствуют о перспективности дальнейшего развития производных кумаринов в качестве потенциальных противосудорожных средств.
Ингибирование α-амилазы и α-глюкозидазы новыми производными β-аминопропиоамидоксимов
Authors: Каюкова Людмила А. , Узакова А. Б. , Байтурсынова Г. П. , Дюсембаева Г. Т. , Шульгау З. Т. , Гуляев А. Е. , Сергазы Ш. Д.
Published: May 2019

В связи с актуальностью проблемы диабета в мире ведется поиск новых противодиабетических средств. Известно о противодиабетической активности производных амидо-ксимов. Нами проведено in vitro тестирование производных β-аминопропиоамидоксимов – оснований и фармакологически приемлемых солей О-ароил-β-(морфолин-1-ил)пропиоамидоксимов и 5-замещенных фенил-3-β-(пиперидин-1-ил и морфолин-1-ил)этил- 1,2,4-оксадиазолов на противодиабетическую активность по ингибированию ферментов α-амилазы и α-глюкозидазы. Выявлены соединения, обладающие выраженными противодиабетическими свойствами; причем ряд 3,5-дизамещенных 1,2,4-оксадиазолов более активен, чем ряд О-ароил-β-аминопропиоамидоксимов. Полученные данные могут быть использованы в дальнейшей in vivo проверке противодиабетических свойств наиболее перспективных образцов с предварительной оценкой их среднетоксической дозы на животных.
Количественное определение суммы флавоноидов в почках каштана конского обыкновенного
Authors: Куркин Владимир Александрович , Белов Павел Викторович , Рыжов Виталий Михайлович
Published: May 2019

Разработана методика количественного определения суммы флавоноидов в почках каштана конского обыкновенного (Aesculus hippocastanum L.) методом дифференциальной спектрофотометрии при длине волны 422 нм в пересчете на рамноцитрин или 7-O-метилкемпферол (3,5,41-тригидрокси-7-метоксифлавон), который является доминирующим флавоноидом данного сырья. Ошибка единичного определения суммы флавоноидов в почках каштана конского обыкновенного с доверительной вероятностью 95 % составляет ±2,23 %. Содержание суммы флавоноидов в почках каштана конского обыкновенного варьирует от (1,24 ± 0,01) % до (2,31 ± 0,03) %.
Природные глубокие эвтектические растворители как альтернативные экстрагенты для извлечения флоротанинов бурых водорослей
Authors: Облучинская Екатерина Дмитриевна , Даурцева Анна В. , Пожарицкая Ольга Н. , Флисюк Елена Владимировна , Шиков Александр Николаевич
Published: May 2019

Природные глубокие эвтектические растворители (ПГЭР) являются перспективными «зелеными» растворителями для экстракции биологически активных веществ из растительного сырья. Это первое исследование, в котором ПГЭР использованы для извлечения флоротанинов из бурых водорослей Fucus vesiculosus L. и Ascophyllum nodosum (L.) Le Jolis. На основе холина хлорида, молочной кислоты, бетаина и глюкозы с различными молярными соотношениями 10 ПГЭР применены для оценки эффективности экстракции полифенолов. Изучено влияние воды в составе водных растворов ПГЭР на извлечение флоротанинов при экстракции. Водоросли экстрагировали методом мацерации в течение 120 мин при 50 °C, соотношение сырье : экстрагент было 1:5. Количественное содержание флоротанинов определяли спектрофотометрически по методу Фолина — Чокальтеу. Максимальное извлечение флоротанинов (60 – 72 %) было достигнуто с использованием 50 – 70 % водных растворов ПГЭР на основе холина хлорида с добавлением молочной или яблочной кислоты, а также яблочной кислоты и бетаина. ПЭГР по эффективности были сравнимы с ацетоном и этанолом.
Pelibatan Orang Tua melalui Kegiatan Ngamen bareng di TK Nurul Amanah Cianjur
Authors: Saidah Ida
Published: May 2019

Penelitian bertujuan  meningkatkan  perhatian orang tua, sekolah, dan lingkungan terhadap perkembangan anak, melalui kegiatan ngamen bareng  diharapkan antara  pendidikan dirumah dan pendidikan di TK tidak terputus, Jenis penelitian  yang dipergunakan adalah penelitian dengan metode survey. Survey pelibatan orang tua dalam kegiatan ngamen bareng  dilakukan  terhadap orang tua murid dan lingkungan, terhadap  perencanaan program kegiatan  ngamen bareng  itu sendiri dan perkembangan anak   di TK Nurul Amanah yang secara langsung terdampak oleh kegiatan  ngamen bareng. Jenis data dan analisis menggunakan penelitian analisis data kualitatif (deskriptif) , yaitu  data dalam bentuk kata, kalimat, dan gambar. Metode penelitian dengan tehnik observasi, wawancara, dan dokumentasi. Hasil penelitian  menunjukkan keterlibatan orang tua murid berada pada tingkat yang baik, keluarga secara aktif terlibat secara langsung , merupakan program unggulan TK Nurul Amanah , disusun secara sistematis, berorientasi pada perkembangan aspek seni dan aspek perkembangan fisik motorik anak.
Analisis Perilaku Home Service Orang Tua terhadap Perkembangan Kemandirian dan Tanggung Jawab Anak
Authors: Gusmaniarti Gusmaniarti , Suweleh Wardah
Published: May 2019

Penelitian ini  memfokuskan pada analisa perilaku orang tua terhadap anak dengan menggunakan metode problem-based di sebuah Lembaga TK Insan cendekia Grabagan tulangan. Perilaku  home service yang berlebihan di lakukan orang tua sangat mempengaruhi perkembangan perilaku mandiri dan tanggungjawab anak.yang terlihat jelas di lingkungan sekolah. Tahapan pengamatan yang lakukan peneliti melibatkan pengembangan materi, validasi ahli dan pengujian lapangan berbasis karakter anak. Metode pengumpulan data menggunakan observasi, wawancara, dokumentasi dan kuesioner.  Hasil penelitian  menggambarkan bahwa  dari 50 siswa paud yang ber umur 5 sampai 6 tahun 80% persen kegiatan kesiapan berangkat sekolah di layani oleh orang tua,90% kegiatan merapikan kamar secara sederhana di lakukan orang tua, 60% aktifitas merapikan permainan di rumah dilakukan orang tua. Data analisis di lakukan secara kualitatif deskriptif.
Social Resonance: Acoustic Information about Upper Limb Movement in Voicing
Authors: Pouw Wim , Paxton Alexandra , Harrison Steven A. , Dixon James A.
Published: May 2019

We show that upper limb movement affects voice acoustics in a way that allows listeners to synchronize to those movements. In this pre-registered motion-tracking study (within-subjects, N = 30), participants listened to vocalizers producing a steady-state phonation while moving the upper limb with a wrist versus an arm motion at different tempos. Listeners were asked to synchronize their own wrist or arm movement with what they perceived in the voice acoustics to be the movement of the vocalizer. Previous research has shown that higher physical impetus gestures can directly affect lower vocal tract activity, leading to peaks in the fundamental frequency (F0; perceived as pitch) and intensity. Here we show that listeners can attune to acoustic information so as to synchronize both in frequency and in phasing with the vocalizer, even with very subtle movements. We interpret the current results in support of a possible ecological psychological approach to speech prosody.
Is Latent Syphilis New Normal among Clinical Presentations of Syphilis? Study from a Tertiary Care Institute
Authors: Padhiyar Jignaben Krunal , Patel Nayankumar Harshadkumar , Buch Jeta , Patel Bhagirath , Chhibber Aseem
Published: May 2019

Introduction: Clinical presentation of syphilis varies widely according to stage of syphilis. Latent syphilis pose special challenge for diagnosis as patient is usually asymptomatic and still infectious.

Material and Methods: Retrospective analysis of Rapid plasma reagin (RPR) positive patients over two years duration from tertiary care institute was carried out.

Results: A total of 32 RPR positive patients were analyzed. Eleven (34.37%) patients had clinical features suggestive of Syphilis, rest 21 (65.63%) patients were found to be positive by RPR without any clinical signs and symptoms. Seven patients (21.8%) had genital ulcerative diseases at the time of presentation.

Conclusion: Our study reports rise in incidence of latent syphilis.
ZnO-modified SnO flower-like microstructures with enhanced photocatalytic performance
Authors: Liang Baoyan , Sun Changhong , Han Danhui , Zhang Yanli , Zhang Wangxi , Zhang Ruijie , Liu Ying
Published: May 2019

A flower-like SnO/ZnO heterojunction photocatalyst with high catalytic activity was synthesized by a simple ultrasonic reaction method. Results show that the SnO/ZnO composites consist of SnO, SnO2, and ZnO. The flower-like structure is made of many SnO nanosheets with a thickness of approximately 20 nm and length of 1–2 μm. A tight interface combination of SnO, SnO2, and ZnO clearly improves the photoactivity of SnO. The photocatalytic performance of the SnO/ZnO composite is much higher than that of ZnO raw materials and SnO sample. The degradation rate of the methyl orange of the SnO/ZnO composite is 99% within 60 min under visible-light irradiation.
Uma discussão analítico-comportamental sobre o autor de violência sexual infantojuvenil
Authors: Moura Cynthia Borges de , Gallo Alex Eduardo , Lima Ariadne Cristina Suzuki de
Published: May 2019

O objetivo do presente trabalho é discutir o comportamento do autor de violência sexual a partir dospressupostos da Análise do Comportamento, bem como as possíveis contribuições dessa perspectiva para acompreensão desse fenômeno. Entender o abuso sexual infantojuvenil, como qualquer outro comportamentohumano, significa compreender sua determinação filogenética, ontogenética e cultural, modelo que recebe onome de seleção por consequências. Nesse modelo, os comportamentos não são “causados” por eventos únicose necessários, mas são selecionados por suas consequências. Identificar quais contingências relacionam-se aocomportamento em questão – entre elas, as características em comum entre abusadores e as variáveis culturaisrelacionadas ao abuso – pode possibilitar o desenvolvimento de estratégias mais seguras de prevenção doscasos de abuso e de intervenção com o perpetrador.
Constructing a gene optimization program based on the ant colony optimization algorithm for Escherichia coli
Authors: Vo Nam Tri , Le Loc Dang , Huynh Viet Quoc , Tran Thuoc Linh , Nguyen Hoang Duc
Published: May 2019

In recombinant protein production, transferring a wild type gene of one organism into another expression host sometime resulted in a low gene expression due to incompatibility between the gene and the expression system. In that case, the target gene needed to be optimized to be more compatible with the expression system through gene optimization process in which nucleotide composition of original gene would be replaced by synonym codons while retaining the protein sequence. In existing gene optimization programs, many optimization algorithms have been applied, such as Genetic Algorithm or Sliding Window, to search for the optimized gene sequence. In this research, we applied the Ant Colony Optimization (ACO) algorithm to construct a gene optimization program. The results showed that the gene after optimization has been improved in codon usage, GC content and reduced the occurrence of factors reducing transcription and translation efficiencies such as polycodon, polynucleotide, repeated sequence, and Shine - Dalgarno sequence. Comparing with some current programs using a gene encoding for human insulin also proved the efficiency in the gene optimization this program. These results have demonstrated the capabilities of applying ACO algorithm in the gene optimization problem.
The Effect of the Targeted Recombinant Toxin DARPin-PE40 on the Dynamics of HER2-Positive Tumor Growth
Authors: Sokolova E. A. , Proshkina G. M. , Kutova O. M. , Balalaeva I. V. , Deyev S. M.
Published: May 2019

The development of targeted toxins based on non-immunoglobulin targeting molecules appears to be one of the most advanced approaches in the targeted therapy of malignant tumors with a high expression of the HER2 receptor. Earlier, we showed that the targeted toxin DARPin-PE40 consisting of the HER2-specific non-immunoglobulin polypeptide (the targeting module) and a fragment of Pseudomonas exotoxin A (the toxic module) exhibits an antitumor effect in vivo against the HER2-positive adenocarcinoma xenograft. In this work, an in-depth analysis of the effect of DARPin-PE40 on the growth dynamics of experimental xenograft tumors was carried out. DARPin-PE40 was shown to inhibit tumor growth at a dose of 25 and 50 g/animal and to cause tumor node reduction at a dose of 80 g/animal, followed by growth resumption at the end of therapy. An evaluation of the tumor growth dynamics revealed statistically significant differences in tumor volume in mice in the experimental groups compared to the control group. The results testify to the potential of using the created targeted toxin as an agent for the targeted therapy of HER2-overexpressing tumors.
Virus-Vectored Ebola Vaccines
Authors: Dolzhikova I. V. , Tokarskaya E. A. , Dzharullaeva A. S. , Tukhvatulin A. I. , Shcheblyakov D. V. , Voronina O. L. , Syromyatnikova S. I. , Borisevich S. V. , Pantyukhov V. B. , Babira V. F. , Kolobukhina L. V. , Naroditsky B. S. , Logunov D. Y. , Gintsburg A. L.
Published: May 2019

The Ebola virus disease (EVD) is one of the most dangerous infections affecting humans and animals. The first EVD outbreaks occurred in 1976 in Sudan and Zaire. Since then, more than 20 outbreaks have occurred; the largest of which (2014-2016) evolved into an epidemic in West Africa and claimed the lives of more than 11,000 people. Although vaccination is the most effective way to prevent epidemics, there was no licensed vaccine for EVD at the beginning of the latest outbreak. The development of the first vaccines for EVD started in 1980 and has come a long technological way, from inactivated to genetically engineered vaccines based on recombinant viral vectors. This review focuses on virus-vectored Ebola vaccines that have demonstrated the greatest efficacy in preclinical trials and are currently under different phases of clinical trial. Particular attention is paid to the mechanisms of immune response development, which are important for protection from EVD, and the key vaccine parameters necessary for inducing long-term protective immunity against EVD.
Immunogenicity of Different Forms of Middle East Respiratory Syndrome S Glycoprotein
Authors: Ozharovskaia T. A. , Zubkova O. V. , Dolzhikova I. V. , Gromova A. S. , Grousova D. M. , Tukhvatulin A. I. , Popova O. , Shcheblyakov D. V. , Scherbinin D. N. , Dzharullaeva A. S. , Erokhova A. S. , Shmarov M. M. , Loginova S. Y. , Borisevich S. V. , Naroditsky B. S. , Logunov D. Y. , Gintsburg A. L.
Published: May 2019

The Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 during the first Middle East respiratory syndrome (MERS) outbreaks. MERS-CoV causes an acute lower-respiratory infection in humans, with a fatality rate of ~35.5%. Currently, there are no registered vaccines or means of therapeutic protection against MERS in the world. The MERS-CoV S glycoprotein plays the most important role in the viral life cycle (virus internalization). The S protein is an immunodominant antigen and the main target for neutralizing antibodies. In the present study, the immunogenicities of five different forms of the MERS-CoV S glycoprotein were compared: the full-length S glycoprotein, the full-length S glycoprotein with the transmembrane domain of the G glycoprotein of VSV (S-G), the receptor-binding domain (RBD) of the S glycoprotein, the membrane-fused RBD (the RBD fused with the transmembrane domain of the VSV G glycoprotein (RBD-G)), and the RBD fused with Fc of human IgG1 (RBD-Fc). Recombinant vectors based on human adenoviruses type 5 (rAd5) were used as delivery vehicles. Vaccination with all of the developed rAd5 vectors elicited a balanced Th1/Th2 response in mice. The most robust humoral immune response was induced after the animal had been vaccinated with the membrane-fused RBD (rAd5-RBD-G). Only immunization with membrane forms of the glycoprotein (rAd5-S, rAd5-S-G, and rAd5-RBD-G) elicited neutralizing antibodies among all vaccinated animals. The most significant cellular immune response was induced after vaccination of the animals with the full-length S (rAd5-S). These investigations suggest that the full-length S and the membrane form of the RBD (RBD-G) are the most promising vaccine candidates among all the studied forms of S glycoprotein.
Adaptation of the Newcastle Disease Virus to Cell Cultures for Enhancing Its Oncolytic Properties
Authors: Yurchenko K. S. , Jing Yi. , Shestopalov A. M.
Published: May 2019

This study focuses on the adaptation of natural Newcastle disease virus (NDV) strains isolated from wild birds to human tumor cells. Many candidates for virotherapy are viruses pathogenic for human. During recombination of genetic material, there always exists a risk of getting a virus with an unstable genome. This problem can be solved by using natural apathogenic viruses as oncolytic agents. The Newcastle disease virus is the causative agent of contagious avian diseases. Its natural strains exhibit an antitumor effect and are considered safe for humans. As shown in earlier studies, the oncolytic properties of natural strains can be enhanced during adaptation to cell cultures, without interference in the virus genome. This study demonstrates that serial passaging increases the viral infectious titer in cancer cells. Moreover, the viability of tumor cells decreases post-infection when Newcastle disease virus strains are adapted to these cell cultures. The findings of this study complement the well-known data on the adaptation of the Newcastle disease virus to human cancer cells. Hence, it is possible to obtain a NDV strain with a more pronounced oncolytic potential during adaptation. This should be taken into account when choosing a strategy for designing anticancer drugs based on this virus.
Perilaku Efektif Guru dalam Melaksanakan Kegiatan Pembelajaran Individu secara Klasikal
Authors: Mustain M
Published: May 2019

Effective classroom teachers don't have many problems, while ineffective classroom teachers are characterized by continuous disruption and chaos. By observing classroom teachers who are effective and ineffective. A good teacher is a teacher who in his PBM is able to inspiring teaching students, he is able to turn on great ideas, great desires for his students, able to develop creative and innovative traits. Based on the focus of the study, this study aims to describe the Effective Behavior of Teachers in Implementing Individual Learning Activities in a classical manner. The teacher's approach is the process, method or action that is approached by a teacher to students to create an effective and efficient learning process, in teaching, the teacher must be clever in using a wise and wise approach, the teacher's view of students will determine attitudes and actions. For teachers, the ability to apply the principles of learning in the learning process will help improve the effectiveness of learning management which in the end can be achieved with the learning objectives formulated.
The Application of Science Concepts in Management Research Reports Based on Scientific Truth
Authors: Hady Hamdy , Henderi Henderi , Putri Dian Mustika
Published: May 2019

The management activity of research report writing requires sufficient knowledge in its preparation. A researcher must learn about the management of understanding scientific concepts, as well as management of research reports that are based on scientific truth. In this study, 1 (one) method was used, namely a literature study of 10 (ten) to support the understanding of scientific concepts according to experts. The concept is a general idea that represents perceived understanding on the basis of reason and logic by someone who then forms a meaning deductively or inductively. Whereas knowledge is what is known or the results of work know. Then scientific truth is related to the quality of knowledge, where every knowledge possessed is viewed from the type of knowledge that is built. Thus scientific truth is an important point in scientific reporting, as the basic foundation of accurate management of report writing and must be displayed in every corner of the report. It is hoped that this research can assist researchers in compiling research reports.

Keywords: Management, Science, Scientific Truth, Research Reports.
Pembuatan Video Profil Sekolah Menengah Atas Negeri 7 Kota Tangerang Selatan Berbasis Audio Visual Sebagai Media Informasi dan Promosi
Authors: Martono Martono , Triyono Triyono , Septiani Roesmita Anggis
Published: May 2019

Media promosi merupakan suatu alat atau sarana untuk memperkenalkan dan menawarkan suatu produk atau jasa atau image atau perusahaan ataupun yang lain agar dapat dengan mudah diketahui oleh masyarakat lebih luas . Dahulu sebelum ada teknologi canggih seperti sekarang ini, media promosi dilakukan dengan cara dari mulut ke mulut. Lalu mulai muncul media promosi berupa surat kabar, radio, majalah, poster, banner dan lain sebagainya. Media-media ini cukup efektif sebagai media promosi tetapi media-media ini tentu punya kelebihan dan kekurangannya masing-masing. Semakin berkembangnya teknologi berkembang juga media promosi yang semakin kreatif, semakin menarik, dan semakin inovatif, diantaranya yaitu media promosi dalam bentuk video profil berbasis multimedia ini. Sekolah Menengah Atas Negeri 7 Kota Tangsel salah satu instansi pemerintahan yang bergerak di bidang pendidikan belum memiliki sarana untuk memberikan gambaran keadaan sekolah kepada masyarakat. Diharapkan dengan dibuatnya video profil ini masyarakat lebih dengan mudah mendapatkan semua informasi dan memiliki gambaran mengenai keadaan sekolah. Tujuan dibuatnya penelitian ini adalah untuk membantu pihak sekolah bagaimana caranya mempromosikan dan memberikan informasi keadaan sekolah kepada masyarakat luas tetapi dengan cara yang lebih kreatif dan tetap efektif mengenai sasaran dengan biaya yang tidak mahal. Penelitian ini menggunakan metode pendataan yaitu observasi dan wawancara. Metedologi pendekatan masalah meliputi definisi masalah, analisa kebutuhan, perencanaan, pembuatan video profile, editing video, uji coba. Penelitian ini tentu saja sangat bermanfaat untuk pihak sekolah selain itu bermanfaat sebagai dokumentasi tentang sekolah. Kata kunci : Media Promosi,Video Profile , Audio Visual
Prototipe Monitoring Kualitas Udara Ruangan Berbasis Awan Adafruit SGP30 Air Quality Sensor
Authors: Kusumah Hendra , Handayani Indri , Susilo Prabowo
Published: May 2019

Kita biasanya menghabiskan sekitar 70-90% waktu di dalam ruangan. Proyek ini meningkatkan kesadaran tentang betapa pentingnya membuka jendela yang ada diruangan secara berkala dan membiarkan udara segar masuk. Di dalam ruangan sangat berpengaruh suasana kenyamanan dalam melakukan berbagai kegiatan yang kita lakukan. Hampir semua ruangan yang kita kunjungi seperti kantor dan restaurant menggunakan Air Conditioner (AC). Kebanyakan para pengguna AC meninggalkan ruangan keadaan AC yang masih hidup. AC merupakan salah satu barang elektronik yang menggunakan daya watt yang besar dan merupakan barang yang sangat pemborosan energi listrik,sehingga effect yang sangat besar terhadap kenaikan biaya listrik dan pembayaran listrik. Hal ini harus diperhatikan pemilik gedung untuk memonitor kondisi bagian-bagian ruangan, sehingga pemakaian energy listrik pada tiap ruangan agar lebih efisien tanpa mengurangi rasa kenyamanan si pengguna ruangan. Pada penelitian ini dilakukan sebuah rancangan untuk memonitoring yang bertujuan untuk memantw au kondisi dari beberapa ruangan dengan menggunakan partikel dan ubidots. Dari sebuah sistem monitoring berbasis web ini,telah berhasil mengetahui berapa jumlah suhu dan kelembaban suatu ruangan, dan juga keamanan yang terdapat dilihat dari jumlah nilai kadar asap yang terdeteksi oleh SHT31-D Temperature & Humidity Sensor. Sistem memonitoring ini dapat sangat berguna untuk diperumahan,restaurant, atau gedung perkantoran yang memiliki jumlah ruangan yang banyak dengan aktifitas yang tinggi.

 Kata kunci  : Suhu, Kelembaban,  Sensor Gas , Kualitas Udara
The Development of Contextual Text Based Exposition Writing Teaching Materials of Class X Students in State 16 Senior High School, Medan
Authors: Rambe Refiansyah Habibie , Gafari M. Oky Fardian , Solin Mutsyuhito
Published: May 2019

This paper deals with The Development of Contextual Text Based Exposition Writing Teaching Materials of Class X Students in State 16 Senior High School, Medan. The method used in the development of teaching material research is the Borg and Gall models which used to develop a product. The product of the learning module that was developed was a contextual text-based exposition writing material for class X students in state 16 Senior High School, Medan. This research and development refers to the theory of teaching material development proposed by Borg and Gall. The finding shows that Teaching Materials Development of Exposition Text Writing Based on Contextual is the development of teaching materials is needed by students and teachers in the learning process. This is due to improving the quality of learning to be better and more interesting. The use of contextual text-based teaching writing materials is considered more effective than the textbooks used by students. This is evidenced by better student learning outcome that is the use of textbooks (Pretest) 70.68% with sufficient categories while the use of teaching materials for exposition text writing is based on contextual (Posttest) 81.40% with good categories. The effectiveness of teaching material based on the results of the pretest to posttest exposition text writing increased with a difference of 10.72%. Based on this, the product developed has been good and tested in improving students' ability in writing exposition texts in class X students in state 16 Senior High School, Medan.
PERCEPTIONS AND ATTITUDE ON USING SOCIAL MEDIA RESPONSIBLY: TOWARD SOCIAL MEDIA LITERACY IN NURSING EDUCATION
Authors: Oducado Ryan Michael Flores , Sales Mhonica Reyes , Magarzo Aira Joy Piz , Panes Patricia Mae Arboleda , Lapastora Joreem Theus Paniza
Published: May 2019

Background: As future professionals, nursing students are expected to exhibit online professionalism and to be responsible users of social media. However, the rapid sharing of information on social media exposes nursing students to the risk and danger of spreading unprofessional behaviors like breaches of privacy and confidentiality.
Objective: This study looked into the nursing students’ perceptions and attitude toward responsible use of social media.
Methods: A descriptive cross-sectional research design was utilized and participated by 298 nursing students in a College of Nursing in Iloilo City, Philippines. The Responsible Use of Social Media Attitude Scale (RUSMAS) created by the researchers was used to collect the data.
Results: Findings indicated that nursing students widely use social media and that nursing students had good perceptions and had positive attitude toward responsible use of social media. A significant difference was found in the attitude of nursing students when grouped according to year level.
Conclusion: Social media continue to gain interest among nursing students and using it responsibly must be continuously upheld. Academic nursing institutions should develop approaches promoting social media literacy in nursing education.
Sleep Apnoea in Patients With Nocturnal Hypertension – a Multicenter Study in the Czech Republic
Authors: HOBZOVA M. , SONKA K. , PRETL M. , VACLAVIK J. , KRIEGOVA E. , RADVANSKY M. , ZAPLETALOVA J. , PLACKOVA M. , KOLEK V.
Published: May 2019

Sleep apnoea (SA) is common in patients with hypertension. Nowadays, limited data on the prevalence of SA in nocturnal hypertension (NH) exist. Therefore, we studied the occurrence of SA in Czech patients and its association with 24-h ambulatory blood pressure monitoring (ABPM), breathing disturbances in sleep, anthropometric data, Mallampati score and Epworth sleepiness scale (ESS) using the Apnea Link device. Undiagnosed SA was found in 72.9 % patients (29.3 % mild, 26.6 % moderate, 17.0 % severe) of 188 patients with NH measured by ABPM. The median of the apnoea-hypopnoea index (AHI) was 12.0 (25th-75th percentile 5.0-23.8). Moderate/severe SA (AHI≥15) was associated with BMI, waist circumference, mean night saturation (SpO2), t90, oxygen desaturation index (ODI), ESS (daytime BP only) (p≤0.032), but not ABPM parameters and Mallampati score (p>0.09). A likelihood of moderate/severe SA was enhanced by ODI>14.5 events/h (odds ratio=57.49, 95 % CI=22.79-145.01), t90>6.5 % (8.07, 4.09-15.92), mean night SpO2<93.5 % (3.55, 1.92-6.59), BMI>29.05 kg/m2 (6.22, 3.10-12.49), circum waist>105.5 cm (3.73, 1.57-8.83), but not by any ABPM parameter. In conclusion, a high incidence of SA (72.9 %) was observed in Czech patients with NH. SA severity was associated with body characteristics and oxygenation parameters, but not with ABMP parameters and Mallampati score.
Cellular Differentiation of Non-Transformed Intestinal Epithelial Cells Is Regulated by Lactobacillus rhamnosus and L. casei Strains
Authors: KOLINSKA J. , ZAKOSTELECKA M. , ZEMANOVA Z. , LISA V. , GOLIAS J. , KOZAKOVA H. , DVORAK B.
Published: May 2019

The aim of this study was to characterize an in vitro modulating effect of three commensal Lactobacillus strains on cellular differentiation of non-transformed crypt-like rat small intestinal cell line IEC-18. IEC-18 was grown on extracellular matrix, with or without presence of Lactobacillus strains. Gene expression of IEC-18 bacterial detection system – such as Toll-like receptors TLR-2, TLR-4, signal adapter MyD88, cytoplasmic NOD2 receptor, inflammatory cytokines IL-18, IL-1β, chemokine IL-8 and enzyme caspase-1 – was evaluated using real-time PCR. Expression and localization of TLR-2, TLR-4, IL-18 and caspase-1 proteins was demonstrated by Western blotting and immunofluorescent staining. Secretion of IL-18 to apical and basolateral surfaces was assayed by ELISA. Our results suggested that L. casei LOCK0919 accelerated differentiation of IEC-18 by stimulating TLR-2, TLR-4, MyD88, IL-18, caspase-1 mRNAs and proteins. L. casei LOCK0919 increased expression and transfer of villin and β-catenin from cytoplasm to cell membrane. Presence of L. rhamnosus LOCK0900 resulted in detachment of IEC-18 layer from extracellular matrix leading to induction of IL-1β, of TLR-2 and IL-8 mRNAs and stimulation of MyD88, caspase-1 and cytosolic receptor NOD2 mRNAs. L. rhamnosus LOCK0908 was not recognized by TLR-2 or TLR-4 receptors. Lactobacilli-IEC-18 crosstalk enhanced immune and barrier mucosal functions.
Aldosterone Modulates Blood Homocysteine and Cholesterol in Coronary Artery Disease Patients – a Possible Impact on Atherothrombosis?
Authors: KAROLCZAK K. , KUBALCZYK P. , GLOWACKI R. , PIETRUSZYNSKI R. , WATALA C.
Published: May 2019

Aldosterone plays a key role in maintaining the homeostasis of the whole organism. Under some circumstances, aldosterone can contribute to the progression of cardiovascular diseases, including coronary artery disease. This study demonstrates that aldosterone associates negatively with some lipidogram parameters and positively with the concentration of homocysteine. These associations are characteristic for coronary artery disease and are not present in control subjects. The findings also indicate that in vitro aldosterone stimulates homocysteine production by rat adrenal glands, which may explain the associations observed with coronary artery disease. Moreover, we have found that aldosterone significantly modulates in vitro platelet reactivity to arachidonate and collagen – aldosterone increases the pro-aggregatory action of collagen, but decreases the pro-aggregatory potential of arachidonate. Therefore, the findings of these in vitro and ex vivo experiments indicate the existence of new pathways by which aldosterone modulates lipid- homocysteine- and platelet-dependent atherogenesis.
Red Palm Oil Supplementation Does Not Increase Blood Glucose or Serum Lipids Levels in Wistar Rats With Different Thyroid Status
Authors: RAUCHOVÁ H. , VOKURKOVÁ M. , PAVELKA S. , VANĚČKOVÁ I. , TRIBULOVÁ N. , SOUKUP T.
Published: May 2019

Red palm oil (RPO) is a rich natural source of antioxidant vitamins, namely carotenes, tocopherols and tocotrienols. However, it contains approximately 50 % saturated fatty acids the regular consumption of which could negatively modify lipid profile. The aim of our study was to test whether 7 weeks of RPO supplementation (1 g/kg body weight/day) would affect blood glucose and lipid metabolism in adult male Wistar rats with altered thyroid status. We induced hypothyroidism and hyperthyroidism in rats by oral administration of either methimazole or mixture of thyroid hormones. Different thyroid status (EU – euthyroid, HY – hypothyroid and HT – hyperthyroid) was characterized by different serum thyroid hormones levels (total and free thyroxine and triiodothyronine), changes in the activity of a marker enzyme of thyroid status – liver mitochondrial glycerol-3-phosphate dehydrogenase, and altered absolute and relative heart weights. Fasting blood glucose levels were higher in HT rats in comparison with EU and HY rats, but the changes caused by RPO supplementation were not significant. The achievement of the HY status significantly increased serum levels of total cholesterol, as well as with high-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol: 2.43±0.15, 1.48±0.09, 0.89±0.08 mmol/l, compared to EU: 1.14±0.06, 0.77±0.06, 0.34±0.05 mmol/l and HT: 1.01±0.06, 0.69±0.04, 0.20±0.03 mmol/l, respectively. RPO supplementation did not increase significantly levels of blood lipids but tended to increase glutathione levels in the liver. In conclusion, RPO supplementation did not induce the presumed deterioration of glucose and lipid metabolism in rats with three well-characterized alterations in thyroid status.
Sociolingvistinis informatikos terminų vartojimo tendencijų tyrimas
Authors: Bačiūnaitė Lina , Paškevičiūtė Greta , Mickienė Ilona Sideravičiūtė
Published: May 2019

Tyrimo tikslas — nustatyti teiktinų ir neteiktinų informatikos terminų dažnumą, jų pasirinkimo priežastis ir galimybes, išsiaiškinti būsimųjų informatikos specialistų kalbinę kompetenciją bei įrodyti, kad būtina skirti daugiau dėmesio ir pastangų formuojant jų profesinės kalbos žodyną. Svarbu pažymėti tai, kad neteiktinus terminų variantus studentai perima iš juos mokančių specialistų. Šio tyrimo objektą sudaro informatikos terminija: teiktini ir neteiktini terminai. Visa tyrimui reikalinga medžiaga buvo surinkta atliekant anketinę apklausą. Anoniminėje anketoje buvo pateikti uždari, atviri ir mišrūs klausimai. Pateikti terminai pasirinkti dėl to, kad jie yra būdingi ne tik informatikų kalbai. Anketos, remiantis sistemine tikimybine atranka, buvo išdalytos Kauno technologijos universiteto studentams, kurie studijuoja informatiką ir dar nėra klausę profesinės kalbos kultūros paskaitų. Tyrimas parodė, kad informatikos specialybės studentai neteiktinus terminų variantus vartoja spontaniškai. Akivaizdu, kad tokie žodžiai lengviau įsigali informatikos specialistų ir studentų kalboje. Kuo greičiau neteiktinas terminas įsigali, tuo sunkiau jį pakeisti teiktinu, ir kuo ilgesnį laiką realija vadinama keliais terminų variantais (ir teiktinais, ir neteiktinais), tuo lengviau įteisinamas teiktinas terminas. Tyrimo rezultatai leidžia daryti prielaidą, kad informatikų ir kalbininkų bendradarbiavimas leistų išvengti dabartinių terminijos klaidų. Neteiktinų terminų įsigalėjimą lemia informacijos stoka, jos neprieinamumas tos srities specialistams. Gana aplaidžiai yra žiūrima į profesinės kalbos kultūros paskaitas, kuriose kaip tik ir turėtų būti išryškinami pagrindiniai terminų kūrimo, vartojimo ir pasirinkimo principai.Raktažodžiai: teiktini terminai, neteiktini terminai, kalbinė kompetencija.
Kaimo pradinių klasių moksleivių sveikatos ir jų ugdytojų sveikatos nuostatos sąsajos
Authors: Puišienė Elena , Ciegienė Rasa
Published: May 2019

Straipsnyje analizuojami kaimo pradinių klasių moksleivių sveikatos ugdymo aplinkos aspektai. Sveikatos ugdymo aplinką sudaro šeima, mokykla, ugdytojas, jo sveikatos nuostata ir sveiko gyvenimo stilius, mokyklos sveikatos priežiūros sistema, kurią reikia orientuoti sveikatos stiprinimo kryptimi, ir kt. Sveikatos ugdymo tikslai — teikti žinių, ugdyti elgesį, įgūdžius ir nuostatas, kurti reikalingą vertybių sistemą. Nuostatą sudaro kognityvinių, emocinių ir veiklos komponentų derinys. Sąmoningą elgseną lemia žmogaus nuostatos, požiūris, vertybinės orientacijos, kurios nėra įgimtos, bet yra išugdomos ir gali kisti ugdymo procese (Jovaiša, 2001). Tyrimo tikslas — nustatyti kaimo pradinių klasių moksleivių sveikatos ir jų ugdytojų sveikatos nuostatos sąsajas. Uždaviniai: 1. Ištirti vaikų sveikatą. 2. Nustatyti ugdytojų sveikatos bendrąją nuostatą ir jos komponentus: kognityvinį, emocinį, bihevioristinį. 3. Išsiaiškinti ugdytojų požiūrį į sveikatą stiprinančius veiksnius. 4. Nustatyti koreliacinius ryšius tarp vaikų sveikatos negatyviosios dalies ir ugdytojų sveikatos nuostatos. Tyrimo metodai: 1. Literatūros šaltinių analizė. 2. Dokumentų analizė. 3. Anketinė apklausa. 4. Matematinė statistika. Tyrimas organizuotas vykdant p. A. Adamkienės fondo inicijuotą projektą „Pagalba kaimo mokykloms“. Tiriamąją imtį sudarė atsitiktiniu būdu parinktose 24 Lietuvos miestelių ir kaimo mokyklose besimokantys 2316 pradinių klasių moksleiviai ir 122 ugdytojai, atsakę į anketos klausimus. Rezultatai rodo, kad daugiausia negatyvios sveikatos kaimo mokyklų pradinių klasių moksleivių yra Tauragės (79,1%), Šiaulių (55,9%), Kauno apskrityse (37,5%). Daugiausia tarp kaimo pradinių klasių moksleivių pasitaiko ydingos laikysenos (29,6%), regos sutrikimų (19,4%) ir širdies sisteminių ūžesių (9,7%) atvejų. Pozityviausia bendroji sveikatos nuostata yra kūno kultūros mokytojų, toliau — mokyklų vadovų, pradinių klasių mokytojų. Statistiškai reikšmingas skirtumas nustatytas tarp kūno kultūros ir pradinių klasių mokytojų grupių vertinimų (p < 0,05). Tarp ugdytojų labiausiai išreikštas kognityvinis sveikatos nuostatos komponentas, t. y. žinių turi pakankamai, o emocinis ir bihevioristinis komponentai išreikšti vienodai, t. y. emocijos ir elgsena, susijusi su sveikata, neadekvati turimoms žinioms. Ugdytojai išskiria tokius pagrindinius sveikatos veiksnius: sveikata — vertybė, mityba, sveiko gyvenimo stilius, o mažiau reikšmingi — sveikatos ugdymasis, sveikatos kontrolė, gydymas, narkotikai, vaistai, veikla, susijusi su sveikata, sveikos aplinkos kūrimas ir fizinis aktyvumas. Esminis koreliacinis ryšys (r = 0,4) nustatytas tarp ugdytojų bendrosios sveikatos nuostatos bei jos bihevioristinio komponento ir mokinių negatyviosios sveikatos. Kaimo pradinėse klasėse ryšys tarp ugdytojų sveikatos nuostatos ir mokinių sveikatos yra menkas todėl, kad vaikų sveiko gyvenimo stiliui ir sveikatai didelės įtakos turi šeima.Raktažodžiai: ugdytojų sveikatos nuostata, pradinių klasių mokinių sveikata.
Paraplegikų gyvenimo kokybė lyties, amžiaus, fizinio aktyvumo, negalios aspektais
Authors: Rakauskienė Eglė , Skučas Kęstutis
Published: May 2019

Tyrimo tikslas — išanalizuoti ir įvertinti paraplegikų gyvenimo kokybę. Tyrimo objektas — paraplegikų gyvenimo kokybės ypatumai amžiaus, lyties, nugaros smegenų pažeidimo trukmės ir lygio, ﬁ zinio aktyvumo aspektais.Tyrimas atliktas 2005 metų vasarą Monsiškių landšafto terapijos ir reabilitacijos centre bei rekreacijos centre „Bal-džio šilas“. Tiriamąją imtį sudarė 41 paraplegikas: 29 vyrai ir 12 moterų.Apibendrinant tyrimo rezultatus galima teigti, kad jauno amžiaus (21—40 m.) paraplegikų gyvenimo kokybė geresnė už vyresnių (41—60 m.). Įvertinus gyvenimo kokybę pagal nugaros smegenų pažeidimo lygį ir trukmę galima teigti, kad geresnė gyvenimo kokybė tų paraplegikų, kurių nugaros smegenys pažeistos daugiau kaip prieš trejus metus, o turinčių šią negalią mažiau nei trejus metus — prastesnė. Aukšto nugaros smegenų pažeidimo (Th1—Th7) paraplegikų gyvenimo kokybė geresnė už turinčių žemą (Th8—Th12).Tyrimo duomenys rodo, kad ﬁ ziškai aktyvių paraplegikų gyvenimo kokybė geresnė, lyginant su ﬁ ziškai neaktyviais. Įvertinus paraplegikų gyvenimo kokybės komponentų raišką lyties aspektu paaiškėjo, kad kai kuriais atvejais vyrų gyvenimo kokybė geresnė nei moterų. Paraplegikų vyrų daugiau nei moterų yra vedę ir gyvena šeimoje, darbą turi taip pat dažniau vyrai. Dauguma vyrų dirba privačiose įstaigose, moterys — visuomeniniais pagrindais. Kai kurių gyve-nimo kokybės komponentų vyrų ir moterų rodikliai panašūs. Pagrindinis vyrų ir moterų pajamų šaltinis — neįgalumo pašalpa, kuri buvo vertinama kaip nepakankama. Didžioji dalis vyrų ir moterų yra įgiję vidurinį išsilavinimą. Tiek vyrai, tiek moterys gyvenimo kokybę judėjimo automobiliu aspektu vertina teigiamai. Paraplegikai vyrai ir moterys savo praėjusio mėnesio psichoemocinę būseną vertina teigiamai.Raktažodžiai: paraplegikų gyvenimo kokybė, nugaros smegenų pažeidimo trukmė, nugaros smegenų pažeidimo lygis.
Lietuvos slidininkų sprinterių rengimo ir jų parengtumo specifiniai bruožai parengiamuoju laikotarpiu
Authors: Strolia Mantas , Skernevičius Juozas , Milašius Kazys
Published: May 2019

Nuo 2002 metų į žiemos olimpinių žaidynių programą įtraukta slidinėjimo sprinto rungtis, kurios varžybinė veikla trunka 2—4 min. Tokios trukmės darbe reikšmingi yra tiek anaerobinis alaktatinis, tiek glikoltinis, tiek aerobinės energijos gamybos būdai. Anaerobinių ir aerobinių energijos gamybos procesų santykis sudaro po 50%. Todėl iš pagrindų keičiasi slidininkų sprinterių rengimo technologija. Visgi tai reikėtų pagrįsti moksliniais tyrinėjimais. Tyrimo tikslas: atsižvelgiant į sprinto rungties reikšmės padidėjimą, išanalizuoti Lietuvos olimpinės rinktinės slidininkų (vyrų) sprinterių rengimąsi parengiamuoju laikotarpiu ir atskleisti jo speciﬁ nius ypatumus, sportininkų organizmo adaptacijos bruožus. Buvo organizuotas dviejų Lietuvos slidininkų sprinterių veiklos tyrimas. Trenerės parengti pratybų planai aptarti su moksline grupe. Sudaryti konkretūs mezo- ir mikro- ciklai, išsamiai aprašyti kiekvienos dienos pratybų planai, numatytas pratybų poveikio kryptingumas (uždaviniai). Fizinis krūvis registruotas sportininkų dienoraščiuose, trenerio žurnale. Atskirų mezociklų veiksmingumui įvertinti buvo atliekami laboratoriniai tyrimai pagal programą „Vankuveris-2010“. Buvo matuojami ﬁ zinio išsivystymo rodikliai, atlikti vienkartinio raumenų susi-traukimo galingumo (VRSG) (Bosco et al., 1983), laiptinės ergometrijos anaerobinio alaktatinio raumenų galingumo (AARG) ir 10 s maksimalių pastangų veloergometrijos testai. Mišraus anaerobinio alaktatinio ir glikolitinio energijos gamybos galingumui įvertinti taikytas 30 s veloergometrijos testas, glikolitiniam galingumui — 60 s veloergometri-jos testas. Pagal šią diagnostikos programą buvo ištirta 14 slidininkų, iš jų 12 rengėsi įveikti ilguosius nuotoliuos, du — trumpuosius. Nustatyta, kad Lietuvos slidininkų sprinterių rengimo turinys ir metodai iš esmės skiriasi nuo ilgųjų nuotolių slidi-ninkų rengimo. Rengiant slidininkus sprinterius, jų anaerobiniam alaktatiniam galingumui ugdyti skiriama iki 20% laiko. Jau antruoju etapu rengiamos glikolitinį galingumą ir ištvermę ugdančios pratybos salėje, lauke. Ugdant aerobinį pajėgumą, vyrauja ﬁ ziniai krūviai, kurių intensyvumas priartėja prie KIR ir sumažėja ﬁ zinio krūvio, kurio intensyvumas mažesnis už ANS intensyvumą, apimtis. Tirti slidininkai sprinteriai parengiamuoju laikotarpiu pasiekė didelius anaerobinio ir aerobinio pajėgumo rodiklius. Išlieka svarbus uždavinys pasiektą specialųjį ﬁ zinį parengtumą išlaikyti įveikiant varžybų nuotolius.Raktažodžiai: slidinėjimo sprintas, specialus fizinis krūvis, fizinis darbingumas, funkcinis pajėgumas, organizmo adaptacija.