bluuebunny/crossref_metadata_2025 huggingface dataset:
Two-Dimensional Modelling of the Mixing Patterns in a Tropical Semiarid Reservoir
Authors: Rocha Sofia Midauar Gondim , da Silva João Victor Barros , Lemos Wictor Edney Dajtenko , de Souza Filho Francisco de Assis , Lima Neto Iran Eduardo
Published: December 2022

Tropical semi-arid regions suffer with recurrent droughts and uncertain water availability, but a few research studies have been conducted to further understand those complexities and their relationships with reservoir hydrodynamics. This study assessed the hydrodynamic processes of a multiple-use reservoir located in the Brazilian semiarid region. The aim was to apply the CE-QUAL-W2 model to understand the lake’s thermal structure and its variabilities in time and space by using the Richardson’s number (Ri) as a reference. Meteorological patterns were also investigated. Results show that: (1) no significant changes were found by analysing the spatial variabilities of stratification; (2) seasonal changes were relevant as more robust stratification stability was observed in the wet period when water availability may be impacted by poor water quality; (3) from meteorological evaluations, rainfall showed a strong coefficient of determination with Ri (r² of 0.77); and (4) a threshold value of 60 mm in monthly precipitation was found as an indication of a stable stratification in the water column. Wind speed and water level partly influenced Ri’s variabilities, while low impact was noted for air temperature and inflow. These results can promote an improvement in water-resources management by linking rainfall regime and reservoir hydrodynamics.
Does Agricultural Intensification Enhance Rural Wellbeing? A Structural Model Assessment at the Sub-Communal Level: A Case Study in Tunisia
Authors: Mhadhbi Fatma , Napoléone Claude
Published: December 2022

We examined the impact of agricultural intensification on the wellbeing of rural communities in a developing country on a sub-communal scale. To measure the interactions within this complex causal relationship, a statistical approach was applied, using partial least squares path modeling (PLS-PM) in its formative structure. Using PLS-PM to simultaneously relate the measured variables (manifest variables) and conceptual variables (latent variables), while incorporating other variables, such as the bioclimate and demography, we characterized the spatial structure of the links between intensive agriculture and wellbeing. The aim was to facilitate government intervention aiming to improve the wellbeing of rural households, while avoiding cumbersome and costly surveys when the scope of public action is extended to a region or a country. Our findings show that the generalization of the productivist system is not always appropriate in developing countries. In our case study, employment in the secondary and tertiary sectors is insufficient to accommodate the rural exodus. In such situations, agricultural intensification leads to poverty and migration to the areas of production and increases disparities in social wellbeing in rural areas.
Information Sharing Game and Value Analysis for the Following Enterprise Applications of Blockchain Technology
Authors: Luo Haiyan , Pan Junlin
Published: December 2022

To address the question of whether small and medium-sized enterprises (SMEs) should follow benchmark companies in establishing a blockchain-based information sharing platform, a two-tier supply chain decision-making problem dominated by retailers and containing two manufacturers of unequal status is analyzed, including the impact on the utility and social welfare of different game players in the supply chain and the supply chain as a whole, taking into account the fact that consumers are sensitive to both price and quality. For this purpose, traditional cooperation models, short-term and long-term models based on blockchain technology for information sharing were constructed and solved, respectively. The findings suggest that in the short term, the establishment of a blockchain technology-based information sharing platform will widen the status gap between manufacturers, making the strong stronger and the weak weaker, with retailers’ profits and social welfare suffering and no change in consumer surplus. In the long term, the quality improvement effect of information sharing will narrow the gap between manufacturers and increase members’ profits, with retailers and the entire supply chain experiencing a significant increase in profits after a short period of time, as well as an increase in consumer surplus and social welfare. In addition, when consumer price sensitivity and quality sensitivity are high, the establishment of a blockchain technology-based information sharing platform is beneficial for the stronger manufacturers, detrimental to the weaker manufacturers, and beneficial for the supply chain in the long term; otherwise, the absence of a blockchain technology-based information sharing platform is beneficial for the weaker manufacturers and the supply chain.
Exploring the Urban Form and Compactness: A Case Study of Multan, Pakistan
Authors: Nadeem Muhammad , Khaliq Nayab , Akhtar Naseem , Al-Rashid Muhammad Ahmad , Asim Muhammad , Codur Merve Kayaci , Mustafaraj Enea , Codur Muhammed Yasin , Baig Farrukh
Published: December 2022

Sustainable development has become an immense challenge, one further complicated by rapid population growth in developing countries. Therefore, analyzing the existing compactness of urban areas is essential for guiding future urban development. Most of the previous research on urban compactness has been conducted in developed countries, whereas limited research has been conducted on urban compactness in developing countries. This study fills this research gap and contributes to the current body of knowledge by offering empirical evidence of compactness measurement based on the existing urban form using Multan city as its context. Multan is a metropolitan city in the growing phase, so measuring its compactness for the promotion of sustainable development is crucial. For this research study, various indicators are adopted from the literature, such as land cover changes, density, land use, road network, congestion index, walkability index, and shape performance index, in order to evaluate compactness. The above-mentioned indicators were analyzed using ArcMap and ERDAS IMAGINE software. This study concludes that Multan city presently lies between compactness and dispersion. To achieve full compactness, highly dense vertical development with a better public transport network should be encouraged. In addition, the prevailing building regulations should be revised to increase the floor area ratio, and incentives should be devised for developers to promote vertical infill development. Moreover, there is an emerging need to formulate and implement compact city policies. By retaining the compact character of Multan city, sustainable development will be promoted. Ultimately, this research study would be a valuable resource for urban planners, decision-makers, and relevant authorities in proposing future compactness policies for sustainable development. This research can be applied to other cities with similar demographic characteristics, population, area, geographical conditions, and structure to that of Multan.
Intuitionistic Fuzzy Rough Aczel-Alsina Average Aggregation Operators and Their Applications in Medical Diagnoses
Authors: Ahmmad Jabbar , Mahmood Tahir , Mehmood Nayyar , Urawong Khamika , Chinram Ronnason
Published: December 2022

Managing ambiguous and asymmetric types of information is a very challenging task under the consideration of classical data. Furthermore, Aczel-Alsina aggregation operators are the new developments in fuzzy sets theory. However, when decision-makers need to use these structures in fuzzy rough structures, these operators fail to deal with such types of values, as fuzzy rough structures use lower and upper approximation spaces. Thus, an encasement of an intuitionistic fuzzy set has a chance of data loss, whereas an intuitionistic fuzzy rough set can resolve the problem of data loss. Motivated by the notion of intuitionistic fuzzy rough sets and new aggregation operators i.e., intuitionistic fuzzy Aczel-Alsina operators, this paper firstly initiates some basic Aczel-Alsina operational rules for intuitionistic fuzzy rough numbers. Secondly, based on these newly defined operational rules, we have developed some new aggregation operators, such as intuitionistic fuzzy rough Aczel-Alsina weighted average (IFRAAWA), intuitionistic fuzzy rough Aczel-Alsina ordered weighted average (IFRAAOWA), and intuitionistic fuzzy rough Aczel-Alsina hybrid average (IFRAAHA) aggregation operators. Moreover, the properties of these aggregation operators have been initiated. These operators can help in evaluating awkward and asymmetric information in real-life problems. The use of aggregation operators in medical diagnosis and MADM is an efficient method that can help in healthcare and decision-making applications. To present an effective use of these developed operators in medical diagnosis and the selection of the best next-generation firewall, we have established an algorithm along with a numerical example to provide authenticity and clarity to the established work. Furthermore, a comparative analysis of the introduced work shows the superiority of the introduced approach.
Estimation of the Friction Behaviour of Rubber on Wet Rough Road, and Its Application to Tyre Wet Skid Resistance, Using Numerical Simulation
Authors: Zhang Lingxin , Wang Rongqian , Zhou Haichao , Wang Guolin
Published: December 2022

Tyre wet skid resistance greatly affects vehicle safety, and it is dependent on the frictional behaviour at the tyre–road interface; however, the currently available numerical models, using the finite element method, either neglect the road roughness or obtain the rightness using expensive computed tomography scans, rendering them inefficient and complex. This study aims to present an estimation method of rubber slides on a rough road, to study tyre wet skid resistance. A three-dimensional rough road model was established, using the harmonic superposition method; the sealing effect of the water film on a wet road was modelled in terms of the pseudo-hydrodynamic bearing effect; the contact pressure, hysteresis friction, and water film hydrodynamic lift force were calculated. Subsequently, a friction model was established that accounted for the road surface morphology, tyre properties, sliding speed, and contact pressure. The accuracy of the friction model was experimentally validated, using the published experimental results. The friction model was then adopted, to conduct a study of the wet skid resistance of a 205/55R16 tyre with two different tread patterns. The simulation results were consistent with the experimental results of braking distance on a wet road. Finally, the effects of road roughness, tread rubber, load, and inflation pressure on wet skid resistance were carried out and analysed. The works in this paper have important significance and practical value for the development of high-performance tyres.
Co-Opetition Strategy for Remanufacturing the Closed-Loop Supply Chain Considering the Design for Remanufacturing
Authors: Su Jiafu , Zhang Fengting , Hu Hongyuan , Jian Jie , Wang Dan
Published: December 2022

The co-opetition strategy between manufacturers and remanufacturers is a key problem of the closed-loop supply chain, especially for the manufacturers often facing decision-making dilemmas when undertaking the environmental responsibilities of the design for remanufacturing (DfRem). Since DfRem is thought to be advantageous for recycling and remanufacturing, it will lower the production costs for remanufacturers but raise them for manufacturers. On the other hand, manufacturers cannot abandon the DfRem because of environmental responsibilities. This work thus formulates three two-period game models of the competition model with patent protection, the competition model without patent protection, and the cooperation model, which consists of a manufacturer and a remanufacturer, to investigate the decision of the manufacturer and remanufacturer co-opetition strategies. The price, the level of DfRem, the recovery rate, the profit, and other factors are compared across the three models using reverse induction and numerical simulation. In addition, we analyzed the influence of different equilibrium solutions on customer willingness to pay for remanufactured products. We find that cooperation not only contributes to the improvement of DfRem but is also the best choice to ensure the stable development of the supply chain system. Manufacturers, in particular, prefer to work together wherever feasible and actively pursue collaboration rather than advocating for patent protection to fend against remanufacturers, even when they have patent rights.
Health Spending Patterns and COVID-19 Crisis in European Union: A Cross-Country Analysis
Authors: Marginean Silvia , Orastean Ramona
Published: December 2022

The COVID-19 virus outbreak generated new questions about the health policy all over the world. Last several years’ evolutions proved that short-term financing solutions could help health systems to deal with shocks, but the research regarding the relationship between the ability to react to unexpected events such as pandemics and steady long-term health policies is limited. The purpose of this paper is to study if EU countries that were consistent in financing national health systems were more prepared to deal with the pandemic shock. Using Current Health Expenditures for 2000–2019, a K-means cluster analysis was conducted, and the 27 EU countries were classified into three groups: high, medium, and low health spenders, with 10, 7, and 10 countries per group, respectively. one-way ANOVA (analysis of variance with one dependent variable) was carried out to identify if there are significant differences between the three groups during the COVID-19 pandemic regarding the general level of preparedness (measured by the Global Health Security Index), impact (measured by excess mortality), and digitalisation as a key factor in implementing successful health and economic policies (measured by the Digital Economy and Society Index). The conclusion was that health systems of the countries from the high health spenders cluster performed better for all three dimensions, followed by medium and low health spenders, showing that better financing could increase the performance and the resilience to future shocks of the health systems.
Aflatoxin B1 Exposure in Sheep: Insights into Hepatotoxicity Based on Oxidative Stress, Inflammatory Injury, Apoptosis, and Gut Microbiota Analysis
Authors: Sui Yuzhen , Lu Ying , Zuo Shoujun , Wang Haidong , Bian Xiaokun , Chen Guizhen , Huang Shucheng , Dai Hongyu , Liu Fang , Dong Haiju
Published: December 2022

The widespread fungal toxin Aflatoxin B1 (AFB1) is an inevitable pollutant affecting the health of humans, poultry, and livestock. Although studies indicate that AFB1 is hepatotoxic, there are few studies on AFB1-induced hepatotoxicity in sheep. Thus, this study examined how AFB1 affected sheep liver function 24 h after the animals received 1 mg/kg bw of AFB1 orally (dissolved in 20 mL, 4% v/v ethanol). The acute AFB1 poisoning caused histopathological injuries to the liver and increased total bilirubin (TBIL) and alkaline phosphatase (AKP) levels. AFB1 also markedly elevated the levels of the pro-inflammatory cytokines TNF-α and IL-6 while considerably reducing the expression of antioxidation-related genes (SOD-1 and SOD-2) and the anti-inflammatory gene IL-10 in the liver. Additionally, it caused apoptosis by dramatically altering the expression of genes associated with apoptosis including Bax, Caspase-3, and Bcl-2/Bax. Notably, AFB1 exposure altered the gut microbiota composition, mainly manifested by BF311 spp. and Alistipes spp. abundance, which are associated with liver injury. In conclusion, AFB1 can cause liver injury and liver dysfunction in sheep via oxidative stress, inflammation, apoptosis, and gut-microbiota disturbance.
Biology and Ultrastructural Characterization of Grapevine Badnavirus 1 and Grapevine Virus G
Authors: Jagunić Martin , De Stradis Angelo , Preiner Darko , La Notte Pierfederico , Al Rwahnih Maher , Almeida Rodrigo P. P. , Vončina Darko
Published: December 2022

The biological characteristics of grapevine viruses, such as their transmission and host range, are important for the adoption of successful prophylaxis strategies. The aim of this study was to investigate the traits of two newly described grapevine viruses widely distributed in Croatia, grapevine badnavirus 1 (GBV-1) and grapevine virus G (GVG). The vine mealybug (Planoccocus ficus) proved to be a vector of GBV-1 and GVG capable of vine-to-vine transmission with overall experimental transmission rates of 61% and 14.6%, respectively. Transmission was also demonstrated by grafting, with an overall transmission rate of 53.8% for GBV-1 and 100% for GVG, as well as by green grafting using the T-budding technique. Symptoms of GBV-1 and GVG were not observed on the woody cylinders of the indicators LN 33, Kober 5BB, 110 Richter and cvs. Chardonnay and Cabernet Sauvignon. Seed transmission and mechanical transmission were not confirmed. Electron microscopy revealed accumulation of GBV-1 particles and viroplasms in the cytoplasm, but no alternations of the cell structure. Infection with GVG revealed the proliferation of tonoplast-associated vesicles inside phloem cells and cell wall thickening.
Using Blood Transcriptome Analysis to Determine the Changes in Immunity and Metabolism of Giant Pandas with Age
Authors: Liu Song , Li Caiwu , Yan Wenjun , Jin Senlong , Wang Kailu , Wang Chengdong , Gong Huiling , Wu Honglin , Fu Xue , Deng Linhua , Lei Changwei , He Ming , Wang Hongning , Cheng Yanxi , Wang Qian , Lin Shanshan , Huang Yan , Li Desheng , Yang Xin
Published: December 2022

A low reproductive rate coupled with human activities has endangered the giant panda, a species endemic to southwest China. Although giant pandas feed almost exclusively on bamboo, they retain carnivorous traits and suffer from carnivorous diseases. Additionally, their immune system is susceptible to aging, resulting in a reduced ability to respond to diseases. This study aimed to determine the genes and pathways expressed differentially with age in blood tissues. The differentially expressed genes in different age groups of giant pandas were identified by RNA-seq. The elderly giant pandas had many differentially expressed genes compared with the young group (3 years old), including 548 upregulated genes and 401 downregulated genes. Further, functional enrichment revealed that innate immune upregulation and adaptive immune downregulation were observed in the elderly giant pandas compared with the young giant pandas. Meanwhile, the immune genes in the elderly giant pandas changed considerably, including genes involved in innate immunity and adaptive immunity such as PLSCR1, CLEC7A, CCL5, CCR9, and EPAS1. Time series analysis found that giant pandas store glycogen by prioritizing fat metabolism at age 11, verifying changes in the immune system. The results reported in this study will provide a foundation for further research on disease prevention and the energy metabolism of giant pandas.
Microplastics in Freshwater: A Focus on the Russian Inland Waters
Authors: Frank Yulia , Ershova Alexandra , Batasheva Svetlana , Vorobiev Egor , Rakhmatullina Svetlana , Vorobiev Danil , Fakhrullin Rawil
Published: December 2022

The low production costs and useful properties of synthetic polymers have led to their ubiquitous use, from food packaging and household products to high-tech applications in medicine and electronics. Incomplete recycling of plastic materials results in an accumulation of plastic waste, which slowly degrades to produce tiny plastic particles, commonly known as “microplastics” (MPs). MPs can enter water bodies, but only recently the problem of MP pollution of sea and fresh waters has become clearly evident and received considerable attention. This paper critically reviews the accumulated data about the distribution of MPs in the freshwater ecosystems of Russia. The available data on MP abundance in the lakes and river systems of the Russian Federation are analyzed (including the large Lakes Baikal, Ladoga, Onego, Imandra and Teletskoe, and the Volga, Northern Dvina, Ob, and Yenisei Rivers within their tributaries) and compared with the data on freshwater MP contents in other countries. In Russia, the main sources of MP pollution for rivers and lakes are domestic wastewater, containing microfibers of synthetic textiles, fishing tackle, and plastic waste left on shores. Among the MPs detected in the surface waters and bottom sediments, polyethylene (PE), polypropylene (PP), and polyethylene terephthalate (PET) particles predominate. The most common types of MPs in the surface freshwaters are fibers and fragments, with fibers prevailing in the bottom sediments. The reported average MP concentrations in the waters range from 0.007 items/m3 at the mouth of the Northern Dvina River to 11,000 items/m3 in the Altai lakes. However, the estimates obtained in different studies must be compared with great precaution because of significant differences in the methods used for MP quantification. The approaches to further improve the relevance of research into MP pollution of fresh waters are suggested.
On quality of new varieties of rye-wheat bread with an unusual formulation
Authors:   Plekhanov Russian University of Economics, Lomovskikh P.А. , Agapkin А.М. ,   Plekhanov Russian University of Economics
Published: December 2022

It is shown that the new varieties of rye-wheat bread of the original formulation, taken from the retail trade, fully comply with the requirements of the standards in terms of organoleptic indicators (appearance, crumb state, smell, and taste) and physico-chemical indicators (humidity, acidity, and porosity). A detailed study of the chemical composition of the samples in terms of the content of starch, sugars, glucose, fructose, fat, and ash with the use of modern equipment confi rmed their content within the normal range.
On neurological manifestations of Madelung»s disease. Clinical cases
Authors:   Far Eastern State Medical University, Khabarovsk, Zakharycheva T. A. ,   RSBHI Regionаl Clinical Hospital named after professor O. V. Vladimirtsev, Khabarovsk, Zhilina M. A. ,   FRHI Medical and Sanitary Unit of the Ministry of Internal Affairs of the Russian Federation for the Khabarovsk Region, Khabarovsk, Shirokova A. S. ,   Far Eastern State Medical University, Khabarovsk, Volynchikova N. V. ,   RSBHI Regionаl Clinical Hospital named after professor O. V. Vladimirtsev, Khabarovsk, Senchikovа I. N. ,   FRHI Medical and Sanitary Unit of the Ministry of Internal Affairs of the Russian Federation for the Khabarovsk Region, Khabarovsk, Vorobievа S. M. ,   FRHI Medical and Sanitary Unit of the Ministry of Internal Affairs of the Russian Federation for the Khabarovsk Region, Khabarovsk, Kunaeva V. A. ,   FRHI Medical and Sanitary Unit of the Ministry of Internal Affairs of the Russian Federation for the Khabarovsk Region, Khabarovsk
Published: December 2022

familial case of Madelung»s disease, a rare disease with an autosomal dominant inheritance type, is presented. The disease debuts in the fifth decade of life, manifests by lipid metabolism disorders in combination with polymorphic comorbid disorders, and has gender-specific clinical differences.
The role of angiogenic factors eNOS / VEGF in the treatment of anaplastic glioma
Authors:   FSBEI HE Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russian Federation, Badu S. K.
Published: December 2022

Introduction: Anaplastic gliomas (AG) account for 6–15 % of all primary brain tumors. These include: anaplastic astrocytoma (AA), anaplastic oligodendroglioma (AO), anaplastic oligoastrocytoma (AOA), and rarer forms — anaplastic pleomorphic xanthoastrocytoma and anaplastic ganglioma. According to the data on these factors, endothelial nitric oxide synthase (eNOS) is promising in terms of the prognostic value of the course of the tumor process. It was reported that a number of vascular VEGF factors interact with eNOS, contributing to the formation of an intra-tumor vascular network, which can create conditions for uneven prolonged hypoxia, leading to the emergence of more stable tumor cells. Its role in the development of a higher anaplasia level has not been studied in isolation, which determines the relevance of this study. The prognostic role of changes in endothelial nitric oxide synthase (eNOS) in the continued growth and malignant transformation of anaplastic gliomas was studied. Results: Histological samples of brain tumors of 22 patients at the University Clinic in Nizhny Novgorod from 2017 to 2019 were examined and verified for the presence of high-grade III glioma, according to the data of the World Health Organization. The average age of the patients was 50.7 years. The material was obtained as a result of surgical removal of recurrent tumors after chemo and radiotherapy. Discussion: The microenvironment of anaplastic glioma plays an essential role in its pathogenesis. More importantly, angiogenesis, which causes the supply of glioma cells with oxygen, growth factors, nutrients, and hormones, is a significant process of tumor dissemination and growth. The degree of microvascular proliferation and angiogenesis was associated with poor survival rate, transition from a lower grade to a high grade, and relapse. In high-grade glioma, such as anaplastic glioma, neoangiogenesis is an important physiological process that provides adequate blood supply for the proliferation, survival, and invasion of glioma cells. Conclusion: The high mortality rate in gliomas underscores the urgent need for effective treatment. The glioma pathogenesis is complex and can be caused by various mechanisms, as evidenced by abnormal activation of tumor angiogenesis and mutation of isocitrate dehydrogenase. VEGF acts as a regulator of angiogenesis and is widely recognized as a critical factor in glioma development and progression. Our results suggest that VEGF and eNOS inhibition may be an effective way to control and/or block endothelial barrier damage and prevent tumor progression.
Las medidas coercitivas unilaterales tomadas por EE. UU. En 2019 y el cambio en la selectividad estratégica del estado venezolano.
Authors: Sira Méndez Sair Ramses
Published: December 2022

El Estado es una relación social, en él se condensan los conflictos pasados, está atravesado por una selectividad que hace que se incline en favor de ciertos y determinados intereses y en detrimento de otros, dicha preferencia dependerá de la correlación de fuerzas que operen en torno a él (tanto interna como externamente). Las Medidas Coercitivas Unilaterales impuestas por los estados poderosos pueden ser consideradas como medios a través de los cuales se puede presionar por un cambio en dicha selectividad (no solo por un cambio de régimen), como se demuestra en el caso venezolano desde 2015. Sobre esto versará el siguiente ensayo que tuvo una orientación metodológica general del tipo investigación cualitativa (investigación interpretativa) y que pretende a través de una caracterización de las Medidas Coercitivas Unilaterales observar los cambios en la selectividad del Estado venezolano.
Aprendizaje Ubicuo y entornos virtuales durante la pandemia por COVID-19 en Perú
Authors: Carrasco Lino Liliana Carmen , Olivera Roque Roxana Haydeé , Huaranga Rivera Liliana , Polanco Tintaya Avelina Nazaria
Published: December 2022

Las TIC transformaron la educación, cambiando paradigmas pedagógicos, metodologías, herramientas y técnicas. Ello, sumado a la pandemia por COVID-19 genera la necesidad de optar por entornos virtuales de aprendizaje y metodologías ágiles como el U-learning. La presente investigación analiza cuan importantes han sido ambos para seguir con la enseñanza, aún en tiempos de emergencia sanitaria. Se empleó el método de revisión sistemática respaldado por el reporte PRISMA, los resultados incluyeron 22 estudios de bases de datos como Dialnet, Scielo, JStore y el repositorio RENATI. Así, se encontró que la mayoría de estudios se vincula a 3 ejes temáticos: la importancia de los Entornos Virtuales de Aprendizaje, la eficacia del aprendizaje ubicuo dentro de los EVA durante la emergencia sanitaria COVID-19 y el surgimiento e importancia del U-learning. Se concluyó que, en efecto, tanto los EVA como el U-learning aportaron a la continuidad del proceso educativo en entornos no presenciales.
A Educação Ambiental frente ao desafio da crise climática, na visão de um material pedagógico da Unesco: reprodutivista ou transformadora?
Authors: Pedrosa Rebekah Farias Cardoso de Britto , Tamaio Irineu
Published: December 2022

A pesquisa consistiu em analisar a compreensão da Educação para o Desenvolvimento Sustentável (EDS) no documento pedagógico da Unesco intitulado “Em preparação para o clima: um guia para as escolas sobre as ações climáticas”. Foram observadas as propostas pedagógicas e a concepção de crise climática do guia, buscando verificar se, nele, o conceito de Educação Ambiental (EA) reflete sobre as raízes sociopolíticas do problema. Utilizamos a metodologia de análise temática, tendo como critério de investigação a presença ou ausência de menção às causas estruturais da crise nas propostas de EA apresentadas. Concluímos que a compreensão de EDS do referido documento propõe apenas ações individuais no âmbito da escola, sem projetá-las para a sociedade como uma pauta emergente.
Assessment of the practice of self-medication by academics of a Nursing School in the south of Minas Gerais - Brazil
Authors: Silva Fabiano Marcos , Oliveira Ruan Pablo Ramos de , Thomazine Gustavo Rodrigo
Published: December 2022

Considered to be one of the problems to public health, the practice of self-medication and drug intoxications are occurrences that classify a large percentage in Brazil. The present study describes the index of self-medication for analgesics and anti-inflammatories among a number of students in the 1st and 7th years of the nursing course of Wenceslaus Braz Nursing School, Itajubá-MG. A field survey was conducted in which a questionnaire containing 17 (seventeen) questions related to self-medication was provided. The research aimed to demonstrate and affirm through the data that were obtained that nursing students, a course that covers total knowledge about benefits and risks caused by medicines, stand out in the practice of self-medication. This practice of self-medication by nursing and nursing professionals results from self-confidence, which originates from their training.
O colapso no sistema prisional e seu reflexo na ressocialização do preso
Authors: Ribeiro Lucas Matheus Malaquias
Published: December 2022

O declínio do sistema prisional brasileiro vem sendo discutido já há bastante tempo. Nos últimos anos, os problemas relacionados a prisão aumentaram de forma exponencialmente, levando o sistema penitenciário a um colapso. A deficiência estrutural e funcional é apontada como um dos principais problemas que cercam a prisão, já que o governo não presta a assistência financeira necessária para dirimir essas questões prisionais que já se arrastam por um longo tempo. Não obstante, o tema dessa monografia pretende investigar o colapso no sistema prisional e seu reflexo na ressocialização do preso. O objetivo é identificar se a crise penitenciária prejudica a reinserção social do condenado. Como problemática o trabalho vai investigar se a ineficiência da aplicação da Lei de Execução Penal e o colapso do sistema prisional reflete na ressocialização do preso. Em relação a metodologia de pesquisa empregada na construção desse trabalho foram utilizados os métodos bibliográficos para analisar o colapso prisional e sua influência da ressocialização, ademais utilizou-se o método de pesquisa hipotético-dedutivo. Não obstante, o estudo também será orientado pela Lei de Execução Penal através de uma análise em relação as políticas criminais adotadas para a ressocialização do condenado.
Projeto Falcão: tecnologia embarcada nas operações aéreas da Polícia Militar do Paraná
Authors: Oliveira Paulo Francisco de , Fávero Wiliam Celestino
Published: December 2022

Este artigo tem por objetivo analisar o Projeto Falcão e as operações aéreas, voltadas à segurança pública, desenvolvidas pela Polícia Militar do Paraná, por meio de seu Batalhão de Polícia Militar de Operações Aéreas. Pretende-se estudar as missões constitucionais competentes à corporação e como o Projeto Falcão pode contribuir para a otimização delas. O projeto prevê a redução de índices de criminalidade por meio da implementação de helicópteros de baixo custo, com alta tecnologia embarcada, aplicados ao radiopatrulhamento aéreo preventivo e repressivo. A fim de se entender suas motivações, faz-se necessário realizar análise da atual conjuntura das operações aéreas desenvolvidas no estado do Paraná, direcionadas aos serviços de segurança pública. Dessa feita, é possível identificar algumas limitações institucionais, dentre as quais destacam-se: a ausência de bases descentralizadas suficientes para realizar cobertura de possíveis apoios policiais em todas as regiões do estado, gerando necessidade de deslocamentos de distâncias maiores com maior demanda de tempo para atendimento; a limitação tecnológica presente nas aeronaves atualmente utilizadas, às quais precisam de equipamentos mais modernos para maximizar a eficiência das ações aéreas. Conclui-se que por meio do Projeto Falcão as operações aéreas praticadas pela Polícia Militar do Paraná serão incrementadas, permitindo novas possibilidades à instituição, nas ações de segurança pública, e superação de limitações atualmente existentes. Para o desenvolvimento do presente artigo, foi realizada pesquisa bibliográfica e revisão de literatura atinente ao tema, bem como, por meio de requerimento administrativo, investigou-se junto à Polícia Militar do Paraná, acerca de informações institucionais que pudessem subsidiar este estudo.
O processo neuroinflamatório e sintomatologia na doença de Alzheimer: Uma revisão bibliográfica
Authors: Andrade Taynara Matos de Oliveira , Gomes Esther Malheiros , Botelho Ana Caroline Rodrigues , Fraga Gabriel Freitas , Ordonho Laura Comeli , Seraphim Julia Coser , Machado Laura de Vasconcelos , Guedes Diego Luiz Leonel , Corrêa Mônica Isaura
Published: December 2022

Este artigo buscou analisar a produção científica sobre o mecanismo da doença de Alzheimer abordando o processo neuroinflamatório e a sintomatologia gerada pelas alterações bioquímicas. A fisiopatologia da doença de Alzheimer é relacionada à síntese das placas de amiloides e à formação dos emaranhados neurofibrilares, que afetam as funções neuronais e podem culminar com a apoptose celular. Estes componentes atuam como fatores pró-inflamatórios, assim ocorrendo a ativação das células gliais e manutenção de um estado inflamatório neurodegenerativo crônico. Além disso, há outros participantes desse cenário, que produzem quimiocinas e citocinas, e atuam como fonte de proteínas do complemento e prostanóides derivados da COX-2. A progressão clínica tem relação direta com o avanço da neuroinflamação, que potencializa a degeneração e morte neuronal, a cada pico inflamatório ocorre a progressão sintomatológica, comprometendo a cognição e execução de atividades básicas de vida diária. O manejo ocorre nos fatores de risco cardiovascular, cuidados com a saúde cerebrovascular e na manutenção da qualidade de vida. A doença é multifatorial e complexa, é necessário o aprofundamento dos conhecimentos acerca do processo da doença e sua sintomatologia, e a investigação para a conjectura do declínio cognitivo e o estabelecimento de prognóstico.
Análise da função sexual de mulheres após o parto
Authors: De Azevedo Monique , De Oliveira Fernanda Pereira , Vital Lysandra Rosa de Andrade Mendanha
Published: December 2022

Objetivo: Identificar se há presença de disfunção sexual em mulheres no período de 45 dias a 6 meses após o parto, sendo ele vaginal ou cesáreo. Metodologia: Trata-se de um estudo transversal analítico, com uma abordagem quantitativa. A amostra foi de 30 puérperas que responderam um questionário online englobando dados sociodemográficos, função sexual e dados obstétricos das participantes, que foram coletados de setembro a outubro de 2022. Resultados: A média de idade das participantes foi de 28,8 anos, 63,3% eram casadas, 36,6% concluíram o ensino superior  e 56,75% tinham renda de 4 salários ou mais. Em relação à diminuição do desejo sexual e falta de lubrificação, 70% das mulheres afirmaram sentir esses sintomas, 63,3 % relataram sentir dor durante a penetração. Quanto ao distanciamento do parceiro, dificuldade em chegar ao orgasmo, medo de ter relações e medo de engravidar novamente, 60% das mulheres apresentavam esses fatores. Conclusão: Este estudo evidenciou que a maioria das mulheres desenvolveram algum tipo de disfunção sexual após o parto, independente da via de nascimento do bebê.
Atualizações sobre a visão geral do Lúpus eritematoso cutâneo
Authors: Braga Jéssica Portes Nico , Cruzeiro Bruna Floriano , Navarro e Melo Isadora Leal Galvão , Pereira Thiago Rodrigues , Pacheco Thaís Guimarães , Da Silva Fernanda Valéria , Fernandes Maria Eduarda Maia , Salgado Nathalie de Oliveira
Published: December 2022

O lúpus eritematoso cutâneo pode ocorrer como um distúrbio independente ou associado ao lúpus eritematoso sistêmico. O lúpus eritematoso cutâneo inclui três categorias de doenças de pele específicas do LE: lúpus eritematoso cutâneo agudo, lúpus eritematoso cutâneo subagudo e lúpus eritematoso cutâneo crônico. A característica chave que une as dermatoses específicas do lúpus eritematoso é a histopatologia, as características histopatológicas comuns compartilhadas incluem uma dermatite de interface vacuolar (degeneração liquefativa da camada basal da epiderme); hiperqueratose; atrofia epidérmica; infiltrado inflamatório de células mononucleares superficiais, perivasculares e perifoliculares; espessamento da membrana basal; e incontinência pigmentar. Em particular, a dermatite de interface é uma característica histopatológica consistente de lúpus eritematoso cutâneo agudo, lúpus eritematoso cutâneo subagudo e lúpus eritematoso discóide (a forma mais comum de lúpus eritematoso cutâneo crônico), mas não é uma característica típica de lúpus eritematoso túmido ou lúpus profundo. A dermatite de interface também pode ser observada em distúrbios não relacionados ao lúpus eritematoso, como a dermatomiosite. Além disso, a maioria das dermatoses específicas do lúpus eritematoso pode ocorrer em associação com o lúpus eritematoso sistêmico, com exceção do lúpus eritematoso tumidus, para o qual o lúpus eritematoso sistêmico associado é raro. As doenças específicas de lúpus eritematoso também podem ocorrer em conjunto com outras doenças de pele específicas de lúpus eritematoso e têm uma abordagem semelhante ao tratamento.
Mielite transversa aguda - relato de caso
Authors: De Sousa Eder Cruz , Da Silva Júnior Wilson Tomaz , Gonçalves Letícia Matos , Pinto Sarah Barreto Pinheiro Souza , Macedo Anamaria Camargo , Masini Marcos
Published: December 2022

Este relato de caso tem uma abordagem estritamente científica, sem conflitos de interesses e respeita as múltiplas facetas éticas. Visa analisar um caso clínico de Mielite Transversa Aguda e suas repercussões para o paciente. A pesquisa se baseia no laudo médico final e dados de prontuário relacionados com a evolução do tratamento. A nosso ver, acrescentar elementos desconhecidos pela literatura atual promove novas evidências científicas que certamente trarão benefícios aos futuros pacientes e à comunidade.
Preparo e caracterização de cerveja artesanal utilizando fruto e plantas medicinais amazônicas
Authors: Squinello Diego Castro , Kluczkovski Ariane Mendonça , de Souza João Vicente Braga , De Moura Neto José Pereira
Published: December 2022

Quase exclusivamente reconhecida como um alimento de alto valor calórico, a cerveja é constituída de numerosos bioativos capazes de promover benefícios à saúde auxiliando o tratamento de diversas doenças como as cardíacas e diabetes tipo II, salientando-se que seja consumida de maneira moderada. O presente trabalho teve por objetivo investigar o potencial de plantas amazônicas utilizadas na medicina tradicional como adjuntos no processo de produção de cerveja, afim de que o produto final tivesse as características medicinais da planta utilizada, para futuramente ser considerada uma “cerveja funcional” trazendo uma possível alternativa no mercado associado à incrementação de compostos com atividades biológicas da flora amazônica em seus produtos. Utilizaram-se plantas com uso consagrado pela etnofarmacologia e com estudos científicos que corroboram esta utilização. Foram preparadas através de processo cervejeiro tradicional utilizando como ingredientes maltes, lúpulo e levedura adquiridos no mercado nacional, 6 tipos de cervejas, sendo incrementadas dos seguintes aditivos: Arrabidaea chica (Crajiru); Genipa americana (Jenipapo); Chenopodium ambrosioides (Mastruz); e Caesalpinia Ferrea (Jucá). As cervejas foram avaliadas quanto ao seu teor de compostos fenólicos, utilizados como marcadores da atividade biológica pretendida e caracterizadas fisico- quimicamente de acordo com a legislação brasileira vigente. Os resultados obtidos foram promissores, com três das cervejas adicionadas de plantas apresentando maior concentração de compostos fenólicos que a cerveja sem adição de nenhuma delas. Além disso, todas as cervejas estiveram dentro dos limites legais de características físico-químicas e não apresentaram grande variação de parâmetros de acidez e pH da cerveja natural sem adição das espécies em estudo.
Determinantes socioeconômicas para o sucesso na atenção materno infantil: uma comparação multinacional
Authors: Souza Vitória Adalgisa Barreto , Leite Débora Cristina Fontes
Published: December 2022

A taxa de mortalidade infantil e a taxa de mortalidade materna são indicadores reconhecidos da saúde geral da população e reflete amplas condições socioeconômicas e o nível educacional, bem como a qualidade e acessibilidade dos serviços médicos (3). Embora melhorias significativas tenham sido feitas na qualidade e no acesso aos cuidados nas últimas décadas, grandes disparidades educacionais, socioeconômicas, geográficas e comportamentais persistem e parecem ser responsáveis ​​por disparidades significativas nas taxas de mortalidade (2). Diante do expressivo reflexo das características sociais da população e economia do país na atenção materno infantil, este estudo visa analisar em 30 países o grau de impacto desta relação.
Perfil epidemiológico de um centro especializado em oftalmologia em Fortaleza-CE
Authors: Macedo Maria Helena dos Santos , Silva Luciana Eloia Quintino da , Marques Carla Patrícia Rodrigues , Macedo Caroline Lopes Aragão de , Ferreira Juliana de Lucena Martins
Published: December 2022

Objetivo: Contribuir para o arsenal literário oftalmológico, no que tange ao perfil ocular da população brasileira. Metodologia: Foi realizado um estudo descritivo e retrospectivo, através da análise de prontuários eletrônicos de pacientes atendidos em um hospital especializado em doenças oftalmológicas (Fundação Leiria de Andrade), abrangendo a população da região metropolitana de Fortaleza – Ceará – Brasil. A amostragem foi realizada de forma aleatória simples e estratificada por idade. Resultado: Dos 382 prontuários selecionados, foi obtido uma idade média de 36 anos e um desvio padrão de 19. Ademais, dentre as doenças mais prevalentes, estavam conjuntivite (51,2%), trauma (12,3%), calázio/hordéolo (7,9%), olho vermelho (6,8%) e blefarite (5,2%). Entre os casos de conjuntivite, a prevalência foi maior entre os meses de fevereiro e abril, que correspondem aos meses chuvosos no estado do Ceará. Conclusão: Os dados epidemiológicos obtidos mostraram uma busca elevada de atendimento oftalmológico pela população economicamente ativa e, principalmente, para doenças como a conjuntivite.
O papel dos macrófagos de perfil M2 no processo de metástase tumoral associado à inflamação crônica
Authors: Fagundes Igor Sampaio , Matos Denise Junqueira , Cervelatti Eliane Patricia
Published: December 2022

Macrófagos se mostram como os leucócitos mais abundantes em biópsias tumorais, destacando seu papel na tumorigênese e sua participação no processo de metástase, principalmente aqueles de perfil M2. Dessa forma, o objetivo no presente trabalho foi esclarecer os mecanismos pelos quais esses imunócitos influenciam nesse processo. Para isso, foi realizada uma revisão de literatura utilizando os termos “neoplasias, macrófagos e metástase” nas plataformas PubMed e Scielo. Foram selecionados 81 artigos publicados entre os anos de 1989 e 2019. Por fim, constatou-se a participação dos macrófagos M2 tanto na formação de tumores diante de um microambiente inflamatório como no estabelecimento e manutenção de nichos metastáticos.
Efeitos do uso da suplementação de probióticos na doença hepática gordurosa não alcoólica
Authors: Góis Lázaro Ricardo Curvelo Ávila , Trindade Leda Maria Delmondes Freitas , Lima Maria Adriely Cunha
Published: December 2022

Introdução: A doença hepática gordurosa não alcoólica (DHGNA), é uma doença silenciosa e progressiva que cursa com acúmulo de gordura nos hepatócitos em indivíduos abstêmios de álcool, sendo bastante prevalente no mundo, estando associada muitas vezes com doenças cardiovasculares e Diabetes Mellitus. Esta enfermidade apresenta um espectro que varia deste um acúmulo de gordura sem causar inflamação até formação de fibrose e cicatrização, podendo evoluir com cirrose e posterior hepatocarcinoma. Objetivo: avaliar o uso da suplementação de probióticos na esteatose hepática não alcoólica e seu efeito em parâmetros metabólicos, de função hepática e inflamatório. Métodos: o presente estudo consiste em uma revisão sistemática realizada a partir de estudos selecionados das bases de dados PMC, BVS e SciELO. Depois de aplicar os critérios de inclusão e exclusão, se definiram 24 artigos para compor a base de dados deste estudo. Resultados: a suplementação com probióticos demonstrou resultados promissores diminuindo os níveis de enzimas hepáticas, além da melhora do perfil lipídico. As cepas mais utilizadas foram as do gênero Bifidobacterium e Lactobacillus que estiveram ambos presentes em (n=20) 83.3% dos estudos. Conclusão: a Doença hepática gordurosa não alcoólica (DHGNA) tornou-se uma doença de prevalência mundial, o uso de probióticos e simbióticos vem demonstrando resultados positivos nesta doença. Contudo ainda não se tem um consenso sobre o assunto sendo necessário mais pesquisas para suprir essa questão.
Descentrar-nos e impensar-nos los estudios organizacionales enclave de una latinoamerica diversa
Authors: Aguilar Wilson Noé Garcés , Coral Lina Juliana Robayo
Published: December 2022

El pensamiento administrativo contemporáneo requiere de una lectura deconstructiva, pues se observa la intención de complementariedad y de avance científico que asigna a los estudios organizacionales por parte del mundo de la academia alejado de la realidad, en tanto busca conservar el statu quo de la administración tradicional.

El documento se propone ensayar sobre ¿y si nos descentramos del canon de la ciencia? ¿y si nos impensamos los estudios organizacionales? ¿y si nos asumimos en tanto investigadores “pertinentes” en una Latinoamérica de diversidad cultural, de luchas, de resistencias y/o alternativas a la modernidad?

Las cuales en consecuencia con lo anterior le dan forma – contenido divergente a los estudios organizacionales en la contemporaneidad.

De ahí que pretender desarrollar pensamiento administrativo podría ser comprendido desde el sentí-pensar, el cual implica una irrupción cognitiva y comprensiva de la administración tradicional para adentrarse en los contextos de diversidad socio- cultural y económica