bluuebunny/crossref_metadata_2025 huggingface dataset:
Every normal-form game has a Pareto-optimal nonmyopic equilibrium
Authors: Brams Steven J. , Ismail Mehmet S.
Published: June 2021

It is well known that Nash equilibria may not be Pareto-optimal; worse, a unique Nash equilibrium may be Pareto-dominated, as in Prisoners’ Dilemma. By contrast, we prove a previously conjectured result: every finite normal-form game of complete information and common knowledge has at least one Pareto-optimal nonmyopic equilibrium (NME) in pure strategies, which we define and illustrate. The outcome it gives, which depends on where play starts, may or may not coincide with that given by a Nash equilibrium. We use some simple examples to illustrate properties of NMEs—for instance, that NME outcomes are usually, though not always, maximin—and seem likely to foster cooperation in many games. Other approaches for analyzing farsighted strategic behavior in games are compared with the NME analysis.
Evaluation of two wild castor (Ricinus communis L.) accessions for cadmium tolerance in relation to antioxidant systems and lipid peroxidation
Authors: Yeboah Akwasi , Lu Jiannong , Gu Shuailei , Liu Haiyan , Shi Yuzhen , Amoanimaa-Dede Hanna , Agyenim-Boateng Kwadwo Gyapong , Payne Joseph , Yin Xuegui
Published: June 2021

The present study was conducted to assess the effect of toxicity of cadmium (Cd) on growth, tolerance index (TI), antioxidant activities, and malondialdehyde (MDA) content in two contrasting wild castor accessions (16-024 and S2-4) via hydroponic experiment (0 and 100 mg/L Cd). The results showed that Cd significantly reduced the growth rate, seedling height, root length, and shoot length of the castor accessions compared to the control, with the Cd effect being more severe in S2-4 than in 16-024. In addition, biomass response including the root and shoot fresh weight and root dry weight decreased in both accessions compared to the control. Compared to the control group, the shoot dry weight of accession S2-4 declined by 21.7%, whereas there was no change in 16-024, suggesting a level of tolerance in 16-024. Analysis of TI on all the growth parameters and biomass content revealed that accession 16-024 was highly tolerant to Cd stress than S2-4. The results further revealed that the expression of the antioxidant enzymes, viz., superoxide dismutase (SOD), catalase (CAT), non-enzymatic antioxidant, glutathione, and MDA content, was influenced by genotype. S2-4 exhibited a higher antioxidant activity (SOD, CAT) and lipid peroxidation activity than 16-024, indicative of oxidative damage from Cd stress.
Geochemical characteristics and genetic families of crude oil in DWQ oilfield, Kuqa Depression, NW China
Authors: Ji Hong , Huang Guanghui , Xiao Wenjie , Zhang Min
Published: June 2021

As one of the most petroliferous oil producing area in Kuqa depression, Dawanqi (DWQ) oilfield is supplying with great attention. In this regard, the geochemical characteristics and oil families from DWQ field were investigated using molecular compounds analysis of GC, GC–MS techniques. The bulk geochemistry of oils from DWQ oilfield displays complicated molecular composition characteristics, including relative higher indices of Pr/Ph (1.4 ~ 4.26, with an average of 2.4), high concentration of light hydrocarbons and certain abundant pentacyclic triterpene and steranes. The C7 light hydrocarbon and isoprenoids ratios indicate the oils were derived from terrestrial and higher plant input in weak oxidizing and reducing environment. Most of the oils are among the mature oils in the study area, except a few samples that are identified as slightly biodegraded by C7 hydrocarbon. Three oil families are identified in DWQ oilfield of Kuqa depression by biomarker analysis and geochemical parameters. The family A shares the attributes with higher amount of tricyclic terpanes, such as C19- C20 tricyclic terpane, higher C24-tercyclic terpane, lower concentration of gammacerane (< 0.6) but poor diasteranes. Family C is characterized with lower content of C19-tricyclic terpane than C20 tricyclic terpane, low C24-tercyclic terpane than C23-tricycli terpane, relative high concentration of gammacerane (> 0.6) but poor diasteranes. The oils of family B are mixed from the two types, showing mixed features of family A and C. The results can shed light for the exploration of the studied area.
Major hepatectomy for perihilar cholangiocarcinoma in elderly patients: is it reasonable?
Authors: Ripamonti L. , De Carlis R. , Lauterio A. , Mangoni I. , Frassoni S. , Bagnardi V. , Centonze L. , Poli C. , Buscemi V. , Ferla F. , De Carlis L.
Published: June 2021

Introduction

We sought to evaluate the effect of age on postoperative outcomes among patients undergoing major liver surgery for perihilar cholangiocarcinoma (PHCC).

Methods

77 patients were included. Patients were categorized into two groups: the “< 70-year-olds” group (n = 54) and the “≥ 70-year-olds” group (n = 23).

Results

Median LOS was 19 both for < 70-year-old group and ≥ 70-year-old group (P = 0.72). No differences in terms of severe complication were detected (44.4% Clavien–Dindo 3–4–5 in < 70-year-old group vs 47.8% in ≥ 70-year-old group, P = 0.60). Within 90 postoperative days, 11 patients died, 6 in < 70-year-old group (11.3%) and 5 in ≥ 70-year-old group (21.7%), P = 0.29. The median follow‐up was 20 months. The death rate was 72.2% and 78.3% among patients < 70 years old and ≥ 70 years old. The OS at 2 and 5 years was significantly higher among the < 70 years old (57.0% and 27.7%) compared to the ≥ 70 years old (27.1% and 13.6%), P = 0.043. Adjusting for hypertension and Charlson comorbidity index in a multivariate analysis, the HR for age was 1.93 (95% CI 0.84–4.44), P = 0.12. Relapse occurred in 43 (81.1%) patients in the < 70-year-old group and in 19 (82.6%) patients in the ≥ 70-year-old group. DFS at 12, 24, and 36 months was, respectively, 59.6, 34.2, and 23.2 for the < 70 -year-old group and 32.5, 20.3, and 13.5 for the ≥ 70-year-old group (P = 0.26). Adjusting for hypertension and Charlson comorbidity index in a Cox model, the HR for age was 1.52 (95% CI 0.67–3.46), with P = 0.32.

Conclusions

 ≥ 70-year-old patients with PHCC can still be eligible for major liver resection with acceptable complication rates and should not be precluded a priori from a radical treatment.
Block-based compressed sensing of MR images using multi-rate deep learning approach
Authors: Haq Ejaz Ul , Jianjun Huang , Huarong Xu , Li Kang
Published: June 2021

Deep learning (DL) models are highly research-oriented field in image compressive sensing in the recent studies. In compressive sensing theory, a signal is efficiently reconstructed from very small and limited number of measurements. Block-based compressive sensing is most promising and lenient compressive sensing (CS) approach mostly used to process large-sized videos and images: exploit low computational complexity and requires less memory. In block-based compressive sensing, a number of deep models are needed to train with each corresponding to different sampling rate. Compressive sensing performance is highly degraded through allocating low sampling rates to various blocks within same image or video frames. In this work, we proposed multi-rate method using deep neural networks for block-based compressive sensing of magnetic resonance images with performance that greatly outperforms existing state-of-the-art methods. The proposed approach is capable in smart allocation of exclusive sampling rate for each block within image, based on the image information and removing blocking artifacts in reconstructed MRI images. Each image block is separately sampled and reconstructed with different sampling rate and reassembled into a single image based on inter-correlation between blocks, to remove blocking artifacts. The proposed method surpasses the current state-of-the-arts in terms of reconstruction speed, reconstruction error, low computational complexity, and certain evaluation metrics such as peak signal-to-noise ratio (PSNR), structural similarity (SSIM), feature similarity (FSIM), and relative l2-norm error (RLNE).
An edge-cloud collaboration architecture for pattern anomaly detection of time series in wireless sensor networks
Authors: Gao Cong , Yang Ping , Chen Yanping , Wang Zhongmin , Wang Yue
Published: June 2021

With large deployment of wireless sensor networks, anomaly detection for sensor data is becoming increasingly important in various fields. As a vital data form of sensor data, time series has three main types of anomaly: point anomaly, pattern anomaly, and sequence anomaly. In production environments, the analysis of pattern anomaly is the most rewarding one. However, the traditional processing model cloud computing is crippled in front of large amount of widely distributed data. This paper presents an edge-cloud collaboration architecture for pattern anomaly detection of time series. A task migration algorithm is developed to alleviate the problem of backlogged detection tasks at edge node. Besides, the detection tasks related to long-term correlation and short-term correlation in time series are allocated to cloud and edge node, respectively. A multi-dimensional feature representation scheme is devised to conduct efficient dimension reduction. Two key components of the feature representation trend identification and feature point extraction are elaborated. Based on the result of feature representation, pattern anomaly detection is performed with an improved kernel density estimation method. Finally, extensive experiments are conducted with synthetic data sets and real-world data sets.
Development of catalytic combustion and CO2 capture and conversion technology
Authors: Yang Zhibin , Lei Ze , Ge Ben , Xiong Xingyu , Jin Yiqian , Jiao Kui , Chen Fanglin , Peng Suping
Published: June 2021

Changes are needed to improve the efficiency and lower the CO2 emissions of traditional coal-fired power generation, which is the main source of global CO2 emissions. The integrated gasification fuel cell (IGFC) process, which combines coal gasification and high-temperature fuel cells, was proposed in 2017 to improve the efficiency of coal-based power generation and reduce CO2 emissions. Supported by the National Key R&D Program of China, the IGFC for near-zero CO2 emissions program was enacted with the goal of achieving near-zero CO2 emissions based on (1) catalytic combustion of the flue gas from solid oxide fuel cell (SOFC) stacks and (2) CO2 conversion using solid oxide electrolysis cells (SOECs). In this work, we investigated a kW-level catalytic combustion burner and SOEC stack, evaluated the electrochemical performance of the SOEC stack in H2O electrolysis and H2O/CO2 co-electrolysis, and established a multi-scale and multi-physical coupling simulation model of SOFCs and SOECs. The process developed in this work paves the way for the demonstration and deployment of IGFC technology in the future.
Recurrence Score Testing Does not Appear to Benefit Patients With Grade 1, Progesterone Receptor-Positive Breast Cancers
Authors: Sibia Udai S. , Sanders Thomas J. , Mylander Charles , Rosman Martin , Tweed Carol , Tafra Lorraine , Jackson Rubie S.
Published: June 2021

Background:

We previously described a risk prediction model (Anne Arundel Medical Center [AAMC] model) based on pathology which may eliminate the need for recurrence score (RS) testing in select early-stage breast cancers. There is a concern that patients in discordant risk prediction groups (AAMC vs. RS) may be overtreated or undertreated if RS testing were omitted.

Methods:

We queried the Surveillance, Epidemiology, and End Results (SEER) database for all breast cancer patients between 2004 and 2015. AAMC low-risk was defined as Grade 1 and progesterone receptor-positive (PR +) tumors, while AAMC high-risk was defined as Grade 3 or estrogen-negative tumors. RS low-risk group was defined as RS < 16 and age ≤ 50 years, or RS ≤ 25 and age > 50 years. RS high-risk group was defined as RS > 25.

Results:

A total of 71,212 cases were analyzed. Of these, 590 were AAMC low-risk/RS high-risk discordant, while 5,596 were AAMC high-risk/RS low-risk discordant. For AAMC low-risk/RS high-risk discordant, 10-year breast cancer- specific survival (BCSS) did not differ for patients who received adjuvant chemotherapy versus those who did not (93% chemotherapy vs. 99% unknown/no chemotherapy, p = .12). Overall survival (OS) was also comparable (92% chemotherapy vs. 91% unknown/no chemotherapy, p = .42). In the AAMC high-risk/RS low-risk discordant group, 10-year BCSS (92% chemotherapy vs. 96% unknown/no chemotherapy, p = .06) and OS (87% chemotherapy vs. 90% unknown/no chemotherapy, p = .52) did not differ between adjuvant chemotherapy and unknown/no chemotherapy groups.

Conclusions:

Adjuvant chemotherapy in the AAMC low-risk/RS high-risk and AAMC high-risk/RS low-risk discordant groups did not improve survival. This supports consideration of omission of RS testing in Grade 1, PR + tumors. Patients with Grade 3 tumors do benefit from RS testing.
One Currency, Two Markets
Authors: Lai Edwin L.-C.
Published: June 2021

This book is for anyone who is interested in the economic analysis of the future of the international monetary system and the USD, and the rising importance of the RMB. It points out the unsustainability of the dollar standard in the long run, that China has unique incentives to internationalize its currency, and how Hong Kong plays an important role. It explains the real reasons for China to internationalize its currency, including using external commitments to force financial sector reforms ('daobi' in Chinese). It applies economic theories accessible to laymen to establish that financial development and openness are crucial for RMB internationalization to succeed, and that greater exchange rate volatility is inevitable due to the 'open-economy trilemma'. Employing the 'gravity model', the book predicts quantitatively that the RMB is likely to be a distant third payment currency after the USD and the euro, but surpassing the Japanese yen in the next decade.
Revolution and Counterrevolution in Poland, 1980-1989
Authors: Paczkowski Andrzej
Published: June 2021

The 1980 general strike in Poland and the establishment of the independent Solidarity movement, which sought to create a state based on civic freedom, were symptoms of a crisis of the communist system. On December 13, 1981, General Wojciech Jaruzelski on behalf of the ruling Communist Party imposed martial law effectively quashing Solidarity. Jaruzelski won the battle, but Solidarity continued itsrevolution in secret and Poland remained politically destabilized. Elections held in June 1989 ended with the defeat of the Communists and the establishment in September of a coalition government inwhich half of the parliamentary seats went to Solidarity, whose representative was also appointed prime minister. The revolution inaugurated in 1980 by the dockworkers of Gdansk had come to fruition. Revolution and Counterrevolution in Poland, 1980-1989 recounts and analyzes the events of this formative decade in Polish history, with particular emphasis on the martial law period. Drawing on extensive archival research, Andrzej Paczkowski examines the origin and form of the Solidarity revolution, the course of the Communist counterrevolution, and the final victory won by Solidarity along with its international repercussions. Andrzej Paczkowski is professor of political studies at the Polish Academy of Sciences, Warsaw. Christina Manetti, Phd, is a translator and researcher of Polish history.
Writing the Nigeria-Biafra War
Authors: Adebanwi Wale , Anyanwu Ogechi E. , Adetayo Alabi , Aito Ofure O.M. , Bryce Jane , Bateman Fiona , Coffey Meredith , Hodges Hugh , Jeyifo Biodun , Njoku Raphael Chijioke , Obi Cyril I. , Okwu Austine , Oyeniyi Bukola , Odoemene Akachi , Ojeleye Olukunle , Opata Christian Chukwuma , Ogede Ode , Uzoigwe G.N. , Ugochukwu Françoise , Uchendu Egodi
Published: June 2021

The Nigeria-Biafra War lasted from 6 July 1966 to 15 January 1970, during which time the post-colonial Nigerian state fought to bring the South-Eastern region, which had seceded as the State or Republic of Biafra, back into the newly independent but ideologically divided nation. This volume discusses the trends and methodologies in the civil war writings, both fictional and non-fictional, and is the first to analyse in detail the intellectual and historical circumstances that helped to shape these often contentious texts. The recent high-profile fictional account by Chimamanda Ngozi Adichie in Half of a Yellow Sun was preceded by works by Ken Saro-Wiwa, Elechi Amadi, Kole Omotoso, Wole Soyinka, Flora Nwapa, Buchi Emecheta, Chukwuemeka Ike and Chris Abani, all of which stronglyconvey the horrific human cost of the war on individuals and their communities. The non-fictional accounts, including Chinua Achebe's last work There Was a Country, are biographies, personal accounts and essays on the causes and course of the war, its humanitarian crises and the collaboration of foreign nations. The contributors examine writers' and protagonists' use of contemporary published texts as a means of continued resistance and justification of the war, the problems of objectivity encountered in memoirs, and how authors' backgrounds and sources determine the kinds of biases that influenced their interpretations, including the gendered divisions in Nigeria-Biafra War scholarship and sources. By initiating a dialogue on the civil war literature, this volume engages a much-needed discourse on the problems confronting a culturally diverse post-war Nigeria. Toyin Falola is the Jacob and Frances Sanger Mossiker Chair in the Humanities and University DistinguishedTeaching Professor at the University of Texas at Austin; Ogechukwu Ezekwem is a PhD student in the Department of History, University of Texas at Austin.
Representing the Dead
Authors: Swift Helen J.
Published: June 2021

Who am I when I am dead? Several late-medieval French writers used literary representation of the dead as a springboard for exploring the nature of human being. Death is a critical moment for identity definition: one is remembered, forgotten or, worse, misremembered. Works in prose and verse by authors from Alain Chartier to Jean Bouchet record characters' deaths, but what distinguishes them as epitaph fictions is not their commemoration of the deceased, so much as their interrogation of how, by whom, and to what purpose posthumous identity is constituted. Far from rigidly memorialising the dead, they exhibit a productive messiness in the processes by which identity is composed in the moment of its decomposition as a complex interplay between body, voice and text. The cemeteries, hospitals, temples and testaments of fifteenth- and early-sixteenth-century literature, from the "Belle Dame sans mercy" querelle to Le Jugement poetic de l'honneur femenin, present a wealth of ambulant corpses, disembodied voices, animated effigies, martyrs for love and material echoes of the past which invite readers to approach epitaphic identity as a challenging question: here lies who, exactly? In its broadest context, this study casts fresh light on ideas of selfhood in medieval culture as well as on contemporary conceptions of the capacities and purposes of literary representationitself. Helen Swift is Associate Professor of Medieval French at St Hilda's College, Oxford.
Livestock for Sale
Authors: Groot Maaike
Published: June 2021

The civitas Batavorum was a settlement on the north-western frontier of the Roman Empire, and it is now the site of numerous archaeological excavations. This book offers the most up-to-date look yet at what has been discovered, using the newest archaeological techniques, about the town and its economy, its military importance, and the religious and domestic buildings it held. It will be essential reading for anyone studying the economy of the Roman provincial countryside or the details of food supply for the Roman army and town.
Kinematic characteristics of longitudinal double folding wings
Authors: Tiegang L. , Guoguang C. , Shuai L.
Published: June 2021

A folding wing is a tactical missile launching device that needs to be miniaturised to facilitate storage, transportation, and launching; save missile and transportation space; and improve the combat capability of weapon systems. This study investigates the aeroelastic characteristics of the secondary longitudinal folding wing during the unfolding process. First, the Lagrange equation is used to establish the structural dynamics model of the folding wing, the kinematics characteristics during the deformation process are analysed, and the unfolding movement of the folding wing is obtained using the dynamic equations in the process. Then, the generalised unsteady aerodynamic force is calculated using the dipole grid method, and the multi-body dynamics equation of the folding wing is obtained. The initial angular velocity required for the deployment of the folding wing is analysed through structural model simulation, and the influence of the initial angular velocity on the opening process is studied. Finally, aeroelastic flutter analysis is performed on the folding wing, and the physical model of the folding wing verified experimentally. Results show that the type of aeroelastic response is sensitive to the initial conditions and the way the folding wing opens.
COVID-19–Related Posttraumatic Stress Disorder Among Jordanian Nurses During the Pandemic
Authors: Qutishat Mohammed , Abu Sharour Loai , Al-Dameery Kholoud , Al-Harthy Ibtisam , Al-Sabei Sulaiman
Published: June 2021

Background:

The coronavirus disease 2019 (COVID-19) outbreak has been declared a pandemic and has affected both patients and health-care workers. This study was conducted to explore the extent of posttraumatic stress disorder (PTSD) experiences among nurses because of the COVID-19 pandemic in Jordan.

Methods:

This study used a cross-sectional study design with a convenience sampling approach. A sample of 259 participants completed the study questionnaires, including a socio-demographic questionnaire and the Posttraumatic Stress Disorder Checklist for DSM-5 between May and July 2020.

Results:

The prevalence of PTSD among the study participants was 37.1%. Most study participants who exhibited PTSD symptoms presented the lowest level of PTSD (17%). The results showed significant differences in overall COVID-19-related PTSD according to the participant’s age (F = 14.750; P = 0.000), gender (F = 30.340; P = 0.000), level of education (F = 51.983; P = 0.000), years of experience (F = 52.33, P = 0.000), place of work (F = 19.593; P = 0.000), and working position (F = 11.597; P = 0.000), as determined by 1-way ANOVA.

Conclusions:

Nurses must be qualified and accredited to cope with reported PTSD cases and their consequences in relation to COVID-19 outbreaks. A close collaboration with a multidisciplinary team is required to recognize, manage, and encourage safety literacy among health-care professionals and individuals diagnosed with or suspected of PTSD due to COVID-19 outbreaks or any other viral outbreaks.
Beyond Plague Pits: Using Genetics to Identify Responses to Plague in Medieval Cambridgeshire
Authors: Cessford Craig , Scheib Christiana L. , Guellil Meriam , Keller Marcel , Alexander Craig , Inskip Sarah A. , Robb John E.
Published: June 2021

Ancient DNA from Yersinia pestis has been identified in skeletons at four urban burial grounds in Cambridge, England, and at a nearby rural cemetery. Dating to between ad 1349 and 1561, these represent individuals who died of plague during the second pandemic. Most come from normative individual burials, rather than mass graves. This pattern represents a major advance in archaeological knowledge, shifting focus away from a few exceptional discoveries of mass burials to what was normal practice in most medieval contexts. Detailed consideration of context allows the authors to identify a range of burial responses to the second pandemic within a single town and its hinterland. This permits the creation of a richer and more varied narrative than has previously been possible.
Autonomous Artificial Intelligence and Uncontemplated Hazards: Towards the Optimal Regulatory Framework
Authors: KOVAC Mitja
Published: June 2021

The issue of super-intelligent artificial intelligence (AI) has begun to attract ever more attention in economics, law, sociology and philosophy studies. A new industrial revolution is being unleashed, and it is vital that lawmakers address the systemic challenges it is bringing while regulating its economic and social consequences. This paper sets out recommendations to ensure informed regulatory intervention covering potential uncontemplated AI-related risks. If AI evolves in ways unintended by its designers, the judgment-proof problem of existing legal persons engaged with AI might undermine the deterrence and insurance goals of classic tort law, which consequently might fail to ensure optimal risk internalisation and precaution. This paper also argues that, due to identified shortcomings, the debate on the different approaches to controlling hazardous activities boils down to a question of efficient ex ante safety regulation. In addition, it is suggested that it is better to place AI in the existing legal categories and not to create a new electronic legal personality.
Processes, Paradoxes and Illusions: Compositional Strategies in the Music of Hans Abrahamsen
Authors: MARCH DANIEL
Published: June 2021

Hans Abrahamsen’s recent music has been the subject of much critical and public acclaim, with his output of the last decade finding a new directness of expression even as it incorporates and develops elements of his musical language that have remained consistent over many years. This article examines the use of compositional processes within a number of these large-scale works – Schnee (2008), Wald (2009), the Double Concerto (2011) and Let me tell you (2013) – and explores the ways in which Abrahamsen generates and controls material through a variety of techniques of transformation and repetition. How smaller-scale systems interact to create music of great allusive complexity is considered through discussion of the variation form of Wald; finally, Abrahamsen’s embracing of types of paradox and illusion are presented as strategies to unlock broader aesthetic issues within his music.
The association of mycoprotein-based food consumption with diet quality, energy intake and non-communicable diseases’ risk in the UK adult population using the National Diet and Nutrition Survey (NDNS) years 2008/2009–2016/2017: a cross-sectional study
Authors: Cherta-Murillo Anna , Frost Gary S.
Published: June 2021

Mycoprotein is a fungal-based ingredient rich in fibre and protein used in meat substitutes called Quorn. Fibre and protein positively regulate glycaemia, lipidaemia and energy intake which are non-communicable diseases’ (NCD) markers. We performed a cross-sectional study to investigate the association of mycoprotein intake with diet quality, nutrient, energy intake and NCD risk within 5507 UK free-living adults from the National Diet and Nutrition Survey from years 2008/2009 to 2016/2017. Dietary approaches to stop hypertension (DASH) and healthy diet index (HDI) were calculated to estimate diet quality. Comparison between mycoprotein consumers (>1 % kcal) and non-consumers, and associations between consumers and nutrient intakes, NCD’s risk markers and diet quality were investigated using a survey-adjusted general linear model adjusted for sex, age, BMI, ethnicity, socio-economic, smoking status, region of residency, total energy, energy density, HDI and non-mycoprotein fibre intake. Mycoprotein consumers (3·44 % of the cohort) had a higher intake of dietary fibre (+22·18 %,P< 0·001), DASH score (+23·33 %) and HDI (+8·89 %) (P< 0·001, both) and lower BMI (−4·77 %,P= 0·00)v. non-consumers. There was an association (P= 0·00) between mycoprotein consumers and diet quality scores (+0·19 and +0·26), high fibre (+3·17 g), total and food energy (+3·09 and +0·22 kcal), but low energy density intakes (−0·08 kcal/g,P= 0·04). Consumers were negatively associated with fasting blood glucose (−0·31 mmol/l,P= 0·00) and glycated HbA1c (−0·15 %,P= 0·01). In conclusion, mycoprotein intake is associated with lower glycaemic markers and energy density intake, and high fibre, energy intake and diet quality scores.
The relationship between dietary intakes and plasma concentrations of PUFA in school-age children from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort
Authors: Buckland Genevieve , de Silva Johnson Sandra , Johnson Laura , Taylor Caroline M. , Jones Louise R. , Emmett Pauline M.
Published: June 2021

An adequate intake of PUFA plays a vital role in human health. Therefore, it is important to assess PUFA intakes in different populations and validate them with biomarkers, but only a few small studies are in paediatric populations. We calculated the dietary intake of PUFA and their main food sources in children and assessed associations between PUFA intakes and plasma proportions. Dietary intakes of 7-year-old children (n 8242) enrolled in the Avon Longitudinal Study of Parents and Children were calculated from the parental-completed FFQ. Plasma PUFA were measured in 5571 children 8 months later, and 4380 children had complete dietary and plasma data. The association between dietary and plasma PUFA proportions was estimated using Spearman’s correlation coefficients, quintile cross-classification and Cohen’s κ coefficients. Mean total PUFA intake was 13·2 g/d (sd 4·2), contributing 6·5 % of total energy intake; n-6 PUFA contributed 5·2 % and n-3 PUFA 0·7 %. The n-6:n-3 ratio was 7·9:1. Mean intakes of EPA and DHA were 35·7 mg/d and 49·7 mg/d, respectively. Most n-3 and n-6 PUFA intakes were weakly correlated with their respective plasma lipids (0·07 ≤ r ≤ 0·16, P < 0·001). The correlation between dietary and plasma DHA was stronger though (r = 0·34, P < 0·001), supported by a modest level of agreement between quintiles (k = 0·32). The results indicate that the FFQ was able to reasonably rank the long-chain (LC) PUFA, DHA, in this paediatric population. Public health initiatives need to address the suboptimal ratio of n-6:n-3 PUFA and very low n-3 LC-PUFA intakes in school-age children in the UK.
Identification of IL-6 as a potential mediator of the myocardial fibrosis that occurs in response to surgery with cardiopulmonary bypass in children with Tetralogy of Fallot
Authors: Liu Hongtao , Zhang Yun , Wu Zhenhai , Zhang Liangqing
Published: June 2021

Background:

Tetralogy of Fallot is a common CHD. Studies have shown a close link between heart failure and myocardial fibrosis. Interleukin-6 has been suggested to be a post-independent factor of heart failure. This study aimed to explore the relationship between IL-6 and myocardial fibrosis during cardiopulmonary bypass.

Material and Methods:

We downloaded the expression profile dataset GSE132176 from Gene Expression Omnibus. After normalising the raw data, Gene Set Enrichment Analysis and differential gene expression analysis were performed using R. Further, a weighted gene correlation network analysis and a protein–protein interaction network analysis were used to identify HUB genes. Finally, we downloaded single-cell expression data for HUB genes using PanglaoDB.

Results:

There were 119 differentially expressed genes in right atrium tissues comparing the post-CPB group with the pre-CPB group. IL-6 was found to be significantly up-regulated in the post-CPB group. Six genes (JUN, FOS, ATF3, EGR1, IL-6, and PTGS2) were identified as HUB genes by a weighted gene correlation network analysis and a protein–protein interaction network analysis. Gene Set Enrichment Analysis showed that IL-6 affects the myocardium during CPB mainly through the JAK/STAT signalling pathway. Finally, we used PanglaoDB data to analyse the single-cell expression of the HUB genes.

Conclusion:

Our findings suggest that high expression of IL-6 and the activation of the JAK/STAT signalling pathway during CPB maybe the potential mechanism of myocardial fibrosis. We speculate that the high expression of IL-6 might be an important factor leading to heart failure after ToF surgery. We expect that these findings will provide a basis for the development of targeted drugs.
Tetralogy of Fallot with pulmonary atresia and aortopulmonary window may mimic common arterial trunk
Authors: Prabhu Sudesh , Keshav Manaswini , Ramachandra Prakash , Raj Vimal , John Colin , Karl Tom R
Published: June 2021

Tetralogy of Fallot with pulmonary atresia is a group of congenital cardiac malformations, which is defined by the absence of luminal continuity between both ventricles and the pulmonary artery, and an interventricular communication. Pulmonary arterial supply in patients with tetralogy of Fallot with pulmonary atresia can be via the arterial duct or from collateral arteries arising directly or indirectly from the aorta (systemic-to-pulmonary artery collaterals), or rarely both. The rarest sources of pulmonary blood flow are aortopulmonary window and fistulous communication with the coronary artery.

Herein, we describe an outflow tract malformation, tetralogy of Fallot with pulmonary atresia and aortopulmonary window, which was misdiagnosed as common arterial trunk. We emphasise the morphological differences.
HRV analysis: undependability of approximate entropy at locating optimum complexity in malnourished children
Authors: Garner David M. , Barreto Gláucia S. , Valenti Vitor E. , Vanderlei Franciele M. , Porto Andrey A. , Vanderlei Luiz Carlos M.
Published: June 2021

Introduction:

Approximate Entropy is an extensively enforced metric to evaluate chaotic responses and irregularities of RR intervals sourced from an eletrocardiogram. However, to estimate their responses, it has one major problem – the accurate determination of tolerances and embedding dimensions. So, we aimed to overt this potential hazard by calculating numerous alternatives to detect their optimality in malnourished children.

Materials and methods:

We evaluated 70 subjects split equally: malnourished children and controls. To estimate autonomic modulation, the heart rate was measured lacking any physical, sensory or pharmacologic stimuli. In the time series attained, Approximate Entropy was computed for tolerance (0.1→0.5 in intervals of 0.1) and embedding dimension (1→5 in intervals of 1) and the statistical significances between the groups by their Cohen’s ds and Hedges’s gs were totalled.

Results:

The uppermost value of statistical significance accomplished for the effect sizes for any of the combinations was −0.2897 (Cohen’s ds) and −0.2865 (Hedges’s gs). This was achieved with embedding dimension = 5 and tolerance = 0.3.

Conclusions:

Approximate Entropy was able to identify a reduction in chaotic response via malnourished children. The best values of embedding dimension and tolerance of the Approximate Entropy to identify malnourished children were, respectively, embedding dimension = 5 and embedding tolerance = 0.3. Nevertheless, Approximate Entropy is still an unreliable mathematical marker to regulate this.
Symbols, Community and Contest: Jhatka and Tobacco in the Politics of Sikh Identity
Authors: KAUSHAL ADITYA
Published: June 2021

Towards the end of the nineteenth century, the process of community-centric awakening was producing the politics of religious identity, mobilisations, and mutual cultural contests between different communities. Punjab being a province that was inhabited mostly by Muslims, Hindus, and Sikhs witnessed an identity based triangular contest between these religious communities where the political leadership of each community picked up cultural symbols to mobilise, organise, and consolidate their respective constituencies. While presenting an account of the symbolic manoeuvrings around jhatka and tobacco in the politics of Sikh identity during the colonial and post-colonial contexts respectively, this article examines the role of symbols in community-centric discourses wherein cultural differences are transformed into cultural discord or antagonism. Here, it is argued that the meanings communicated and deciphered through such symbols need to be comprehended by locating their articulations in the field of inter-community power relations.
The Making of Gale's Making of Modern Law
Authors: Graff Bennett
Published: June 2021

Bennett Graff, senior acquisitions editor at Gale, reviews the origins and current composition of The Making of Modern Law, a series of individual collections of digitized primary sources devoted to legal history. This overview explores the rationale behind the development of these collections and the research needs that they meet.
An Improved Representation of Aerosol Wet Removal by Deep Convection and Impacts on Simulated Aerosol Vertical Profiles
Authors: Shan Yunpeng , Liu Xiaohong , Lin Lin , Ke Ziming , Lu Zheng
Published: June 2021

We introduce a physics‐based aerosol wet removal scheme with unified treatments of aerosol transport and removal by convective clouds into the Community Atmosphere Model version 6. Since several important physical processes are still neglected or poorly represented in this new physics‐based scheme, we develop secondary improvements to the parameterizations of aerosol activation, resuspension, and cloud‐borne aerosol detrainment in this new scheme. Changes in the aerosol wet removal scheme cause tropospheric aerosol concentrations to decrease to different extents: compared to the control run, the physics‐based scheme significantly decreases aerosol burdens by up to 60% over the southern Pacific Ocean, whereas the secondary improvements mitigate the decreasing tendency. The burden changes also depend on aerosol chemical components: the sulfate mass decrease is compensated by secondary production, black carbon (BC) is effectively removed via increasing the hygroscopicity of particulate organic matter from 0 to 0.2, and dust shows the most spatially heterogeneous changes. Simulated aerosol profiles are evaluated against aircraft‐based observations over the Pacific and Atlantic Oceans. The secondary‐improved scheme reduces the overestimations of upper tropospheric BC and sea salt concentrations by a factor of 10 and 1,000, respectively, and reproduces the dependence of BC mass decrease rates on cloud types. Consideration of convective cloud‐borne aerosol detrainment plays the most important role in enhancing the aerosol wet removal and decreasing the positive biases of tropospheric BC and sea salt concentrations. We also summarize unresolved issues related to convective cloud genesis and microphysics, cloud‐borne aerosol evolution, and BC and dust emissions.
Precipitating Solar Wind Hydrogen as Observed by the MAVEN Spacecraft: Distribution as a Function of Column Density, Altitude, and Solar Zenith Angle
Authors: Henderson Sarah , Halekas Jasper , Lillis Robert , Elrod Meredith
Published: June 2021

The Mars Atmosphere and Volatile EvolutioN (MAVEN) mission observes precipitating solar wind hydrogen ENAs in the upper Martian ionosphere with various instruments onboard. These precipitating solar wind hydrogen atoms result from the direct interaction between the solar wind and Mars's extensive hydrogen corona, creating a beam of particles traveling at solar wind speed that can penetrate deep into the ionosphere of Mars. Using particle data collected by both the Solar Wind Ion Analyzer (SWIA) and Neutral Gas and Ion Mass Spectrometer (NGIMS) onboard MAVEN, we seek to characterize the global behavior of these particles. By using a combination of energy spectra and neutral gas density data, we are able to determine the behavior of this particle population as a function of altitude, column density, and solar zenith angle. Through our analysis, we see that these precipitating solar wind hydrogen ENAs undergo multiple charge exchange interactions and ultimately scatter significantly at an altitude of 160 km or column density of 5 × 1016 cm−2. This observed column density at which equilibrium is reached is at a value ∼17 times greater than the theoretical value. We also demonstrate that this particle population's energy flux follows a cosine dependence of solar zenith angle, as is predicted by models.
Architecture, Kinematics, and Tectonic Evolution of the Principal Cordillera of the Andes in Central Chile (∼33.5°S): Insights From Detrital Zircon U‐Pb Geochronology and Seismotectonics Implications
Authors: Mardones Verónica , Peña Matías , Pairoa Sebastián , Ammirati Jean‐Baptiste , Leisen Mathieu
Published: June 2021

We assess the role of inherited structures on the Meso‐Cenozoic tectonic evolution of the main Andean Cordillera in central Chile (33°30′S‐34°S). Based on extensive field mapping, U‐Pb geochronology and palinspastic restorations along the Yeso and Volcán river valleys, we propose a tectono‐stratigraphic model for the evolution of a hybrid fold‐and‐thrust belt, originated from the inversion of Mesozoic extensional basins. With these results, we highlight the structural graben configuration of the Yeguas Muertas and Nieves Negras depocenters, as evidenced by synextensional deposition of the Río Damas and Lo Valdés Formations, controlled by normal faulting. The uppermost Cretaceous evolution can be approached through the analysis of the Las Coloradas Unit (ULC), which overlies the volcanic rocks of the upper Colimapu Formation and can be correlated, north of 32°S, with the Juncal Formation, and south of 35°S, with the Plan Los Yeuques Formation. The contractional Neogene‐Quaternary deformation in the fold‐and‐thrust belt domain studied in this work, accommodated 27–28 km of minimum crustal shortening. The Neogene‐Quaternary deformation that generated the final uplift of the Andes, has a close relationship with preexisting inverted Mesozoic structures. These structures deform the volcano‐sedimentary Abanico Formation, deposited since the late Eocene, based on new U‐Pb detrital zircon data. We propose that the active seismicity observed in the eastern border of the Principal Cordillera, located to the east of Santiago, can be associated with major crustal faults, as the Estero de Yeguas Muertas‐Baños Colina fault system and the Chacayes‐Yesillo fault.
Syn‐Subduction Strike‐Slip Faults Shape an Accretionary Orogen and its Provenance Signatures: Insights From Sikhote‐Alin in NE Asia During the Late Jurassic to Early Cretaceous
Authors: Liu Kai , Xiao Wenjiao , Wilde Simon A. , Zhang Jinjiang , Alexandrov Igor , Kasatkin Sergey A. , Ge Maohui
Published: June 2021

Sedimentary rocks provide key information on source‐to‐sink systems and the regional expression of plate tectonics. The abruptly changing provenance signature of sedimentary rocks is commonly ascribed to changes in the source regions, such as continental collision events, the rise of mountain chains, reorganization of river systems and climatic change. However, moving the positions of the sinks (depocenters) geographically can also change the provenance record, but this is rarely considered. Typically, large‐scale strike‐slip faults can transport depocenters for long distances, thus altering the provenance information. In this study, we present a systematic investigation of the provenance changes in the Sikhote‐Alin orogenic belt in the Russian Far East to evaluate this process. The Central Sikhote‐Alin Fault is a margin‐parallel strike‐slip fault that developed along the NE Asian continental margin from the late Mesozoic. Our new detrital zircon U‐Pb data, together with a compilation of geochronological data, indicate two different types of provenance signatures available: the sediments to the west of the fault were mainly derived from the adjacent Central Asian Orogenic Belt, but to the east of the fault, they were mainly supplied from the Korean Peninsula, which is several hundred kilometers away. It is proposed that these different sedimentary rocks were juxtaposed by syn‐ and post‐subduction sinistral displacements along the fault, and were not related to local variations in the source regions. Thus, understanding the shifting positions of depocenters is important when decoding provenance change because lateral displacement is critical for reconstructing regional paleogeography along oblique convergent plate margins.
Characteristics of the Basal Interface of the Martian South Polar Layered Deposits
Authors: Khuller Aditya R. , Plaut Jeffrey J.
Published: June 2021

We expand on previous studies of the South Polar Layered Deposits' (SPLD) basal interface using data acquired by the Mars Advanced Radar for Subsurface and Ionospheric Sounding (MARSIS) to obtain detailed maps of elevation, topography, and reflected radar power. Using these maps, we derive the thickness (ranging from 0 to 3.7 km) and volume of the SPLD (∼1.60 × 106 km3). While most basal interfaces reflect less power than the average SPLD surface, areas with basal echo power exceeding that of the surface are widespread throughout the SPLD, including at the location of potential subglacial water bodies in Ultimi Scopuli. The occurrence of these high basal echo power signatures appears to be largely frequency independent in MARSIS data. While the cause of the relatively high basal echo power values is uncertain, our observations suggest that this behavior is widespread, and not unique to Ultimi Scopuli.
DW1 Tidal Enhancements in the Equatorial MLT During 2015 El Niño: The Relative Role of Tidal Heating and Propagation
Authors: Kogure Masaru , Liu Huixin
Published: June 2021

Ground‐based and satellite observations have shown that the tidal component DW1 in the equatorial mesosphere and lower thermosphere (MLT) was enhanced in July–October 2015, which was an intense El Niño year. This enhancement is reproduced in the 21 years reanalysis‐driven model simulation by the Ground‐to‐topside model of Atmosphere and Ionosphere for Aeronomy (GAIA). Our analysis shows the (1,1) Hough mode dominates this tidal enhancement, and its peak amplitude was 7.4 K (74%) higher than that under neutral (non‐ENSO) conditions at 90 km. The corresponding tidal heating was found to increase by 0.4 mWkg−1 (5%), which can explain 0.5 K (7%) of the (1,1) enhancement. To explain the remaining 6.9 K (93%) of the enhancement, we quantitively examined the upward propagation condition by calculating the vertical wavenumber and the latitudinal shear of the zonal wind. The analysis reveals that the vertical wavenumber between 18 and 60 km was one standard deviation smaller than that under neutral conditions. The latitudinal zonal wind shear also decreased at 18 N/S° in 18–30 km. These results suggest smaller dissipation and damping of the (1,1) mode during its upward propagation, which dominantly contributed to the tidal enhancement at 90 km altitude. This decrease in the vertical wavenumber and the wind shear can be reasonably explained by the eastward phase of the quasi‐biennial oscillation (QBO) in the lower stratosphere. This study suggests that the overlapping of the 2015 El Niño with the eastward phase of the QBO induced the large enhancement of the DW1.