bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Study on Quorum Modulatory Effect of Selected Medicinal Plants on Chromobacterium violaceum ATCC 12472 (MTCC 2656)
Authors: Vijayan Nadasha Koonath , Tanimu Habibu , Sukumaran Bindhu Omana
Published: August 2024

Among the main global health concern is the rampant rise in antibiotic resistant bacteria. One of the appealing and promising strategies to combat this menace is to target the adaptive mechanism called quorum sensing (QS) used by bacteria to survive. Exploratory research on anti-QS compounds derived from natural products has been a promising area. The present study investigated methanolic extracts from 26 plants to compare their anti-QS activity using the QS biosensor strain Chromobacterium violaceum American Type Culture Collection (ATCC 12472) (Microbial Type Culture Collection MTCC2656). QS-mediated violacein pigment inhibition was carried out using agar well diffusion method with concentrations ranging from 10 mg/ml to 100 mg/ml. Leaf extracts of Mangifera indica and Pimenta dioica and peel extract of Punica granatum were the only three plants found to exhibit violacein inhibitory potential till 10 mg/ml. The result of the minimum inhibitory concentration (MIC) showed 1.6 mg/ml for M. indica and P. dioica and 6.25 mg/ml for P. granatum. Further, violacein inhibitory properties of these extracts at and below MIC were evaluated by well diffusion assay (qualitative) and by flask incubation assay (quantitative). The zone of inhibition (well diffusion assay) was found to be 14.51 ± 0.63 mm to 10.37 ± 0.68mm for M. indica, 15.23 ± 0.57 mm to 9.62 ± 1.29 mm for P. granatum and 17.01 ± 0.1 mm to 13.14 ± 0.18 mm for P. dioica. The inhibitory effect of the plant extracts via quantitative assay on violacein ranged from 83-49%, 89-81%, and 89-49% for M. indica, P. granatum, and P. dioica respectively. Our findings suggested the potential of M. indica, P. granatum, and P. dioica methanolic extracts as a source of effective inhibitors of QS-mediated violacein production.
Utilizando a Extração Pesqueira para Ensinar Gráficos, Funções e Temas Ambientais em duas Escolas Pública no Município de Maraã - Amazonas.
Authors: Mendes dos Santos Edilanê
Published: August 2024

Por meio de uma pesquisa etnográfica, buscou-se compreender os processos da atividade pesqueira realizada no município de Maraã, interior do Amazonas e a partir disso, aplicou-se conceitos matemáticos voltados ao processo de ensino e aprendizagem de gráficos, tabelas e equações nas turmas do 8º ano do Ensino Fundamental em duas escolas públicas localizadas no município em questão. Além da contextualização da pesca, foi propicio fazer uso da interdisciplinaridade, uma vez que foi levado ao estudante conceitos relacionados a geografia e história da região. Baseado numa pesquisa bibliográfica, buscou-se mostrar aos alunos a importância de se preservar o Meio Ambiente, uma vez que a economia desta localidade depende estritamente dos recursos naturais ali presentes.
Formação de professores e Etnomatemática
Authors: LUCAS JOSÉ LUCAS MATIAS DE EÇA , Bete Zulma Elizabete de Freitas Madruga , Jurema Jurema Lindote Botelho Peixoto
Published: August 2024

A formação continuada do professor de matemática poderá ser enriquecida com o debate dos processos de ensino e aprendizagem, considerando uma educação emancipadora, voltada para o exercício da cidadania e preservação da identidade cultural. O objetivo desta pesquisa é discutir as potencialidades que a exploração do acarajé, culinária regional, pode promover em uma formação continuada com professores de matemática visando a construção do conceito Etnomatemática. Para tanto foi desenvolvida uma proposta de formação no âmbito de um programa de mestrado, articulado com a secretaria de educação de um município do interior da Bahia. A proposta formativa foi desenvolvida em oito encontros, segundo o método de conversação dialógica, envolvendo as dimensões: conhecendo os professores, fundamentação teórico-prática, desenvolvimento da atividade quitute afro-baiano acarajé e sistematização/problematização da perspectiva Etnomatemática. Os resultados apontam que os professores ampliaram suas percepções em relação ao conceito de cultura, Educação Matemática e identidade cultural, compreendendo como articular vivências sociais no ensino.
The Bilateral Inheritance System in Islamic Family Law: Fairness, Equality, and Mutual Exchange Perspectives
Authors: Aniroh Reni Nur , Nasution Khoiruddin , Sodiqin Ali
Published: August 2024

This article aims to demonstrate that bilateral inheritance is a system of inheritance that is intended to embody the principles of equal justice in Islamic family law. Hazairin, the pioneer of bilateral inheritance, has initiated the implementation of these principles. However, there are still some issues that need to be addressed in some circumstances. This study employs a juridical legal approach, examining it through the lens of John Rawls' theory of justice and Mubādalah Faqihuddin Abdul Kodir's theory. The studied material consists of notions and perspectives concerning the distribution of inheritance in Islamic law, derived from the Qur’an, hadith, and the viewpoints of ulama and legal professionals. The article's conclusion demonstrates that, according to John Rawls's theory of justice and Mubādalah Faqihuddin Abdul Kodir's theory, bilateral inheritance, when interpreted in a mutually equitable manner, establishes equal positions for men and women in terms of both lineage and inheritance, based on their individual circumstances. Under circumstances where women, like men, can inherit all assets as sole heirs without contravening the explicit restrictions of the text, Furthermore, the allocation of inherited assets can be executed without any complex calculations or meticulous planning, since these assets can be fully utilized without any surplus or diminishing the portion received by the heirs. This essay aims to highlight Hazairin's innovative proposal for ensuring fair treatment in inheritance disputes while also addressing the theological issues that have been overlooked. Consequently, it is possible to examine Hazairin's thesis by employing Rawls' theory of justice and Mubjadi Faqihuddin's theory.
Living Qur’an, Niqab, and Islamic Law: A Study at Mambaush Sholihin Islamic Boarding School, Gresik, East Java
Authors: Toriquddin Moh , Faizin Nur , Hamidah Tutik , Hamdan Ali , Muhammad Muhammad
Published: August 2024

Two impressions emerging from wearing a niqab (face veil), i.e., piety and radicalism, are deeply embedded in public perception. The obligation to wear the niqab for female students at an Islamic boarding school known to be moderate and cultural, such as the Mambaush Sholihin Islamic Boarding School, is an interesting issue to study. In this current study, the empirical legal method was used, based on the theory of the living Qur’an and Islamic law. Data collection techniques included in-depth interview, literature review, and focus group discussion. The findings reveal that in the opinions of the Islamic boarding school caretakers, the use of the niqab at Mambaush Shalihin does not lead to an exclusive attitude, but rather to code of conduct, that limits the interaction between men and women. However, some students respond to this conduct differently and they view it as a form of coercion, giving rise to an attitude of resistance expressed when they are outside the school, whereas others still prioritize an attitude of obedience and submission to the kyai. On the other hand, some people in the public perceive this as a form of change in the Islamic boarding school towards radicalism while others believe that the school remain on the principles of the moderate teachings of Ahl Sunnah wal Jamaah. In practice, wearing the niqab at Mambaush Shalihin is a form of the Living Qur’an in relation to the command to cover the awrah(private parts) for women. Meanwhile, according to Islamic law, the law on wearing the veil is different among the scholars of the four schools of thought. This article argues that the use of the veil in Islamic boarding schools is not affiliated with a particular madhhab but rather aims to discipline female students who study in the same room as male students. This is indicated by the non-obligation to wear any face veil for female students who have not yet studied in college, i.e., junior and senior high school levels.
Law, Ethics, and Hadith Ahkam: An Analysis of Fatwa MUI in the Perspective of Progressive Interpretation
Authors: Anam Wahidul , Sulaeman Mubaidi
Published: August 2024

This article discusses the progressive interpretation of the ahkam hadith in MUI Fatwa Number 83 of 2023 which relates to the law of support for the Palestinian struggle, with an emphasis on its relation to the boycott of products that support Israel. The main focus of this research is an in-depth and critical exploration of the relevance of certain hadiths in the context of the Palestinian struggle, as well as their application to the boycott policy as a form of solidarity action. This article adopts the perspective of Abdullah Saeed's progressive interpretation of listening to the hadiths that were used as the basis for the MUI fatwa. The method used in this article is a qualitative method with a hadith ahkam and an ethical-legal approach. The data collection technique is a literature study in the form of a study of hadith, journal articles, books related to law, ethics, and hadith ahkam regarding fatwas. The results of this study provide deep insights into the relevance of ahkam traditions in supporting the Palestinian cause in the context of boycotts. Progressive thinking on these traditions is integrated with arguments to strengthen boycotts in response to human rights violations and economic policies that support Israeli occupation. The article also discusses the potential impact of the boycott, both from an economic point of view and as a political instrument that can exert international pressure. Thus, this article not only attempts to detail the progressive interpretation of hadith ahkam in MUI Fatwa No. 83 of 2023 but also critically relates it to the boycott strategy, contributing to progressive Islamic literature and Islamic law studies in viewing the Israeli-Palestinian conflict.
Fulfillment of The Living Rights of Children the Victims of Divorce in the Muslim Community of Lombok, Indonesia
Authors: Abdullah Abdullah , Syahri Akhmad , Hamamah Fatin , Gafur Abd. , Sholeh Ahmad
Published: August 2024

This research examines the effectiveness of fulfilling the livelihood rights of children, the victims of divorce, the inhibiting factors, and how alternative solutions solve the problem of providing for children in Lombok Island, West Nusa Tenggara, Indonesia. This research is field research. The research data includes primary data and secondary data. The primary data is data obtained from respondents, informants, and resource persons. Data collection techniques in this research used interview techniques, observation, and documentation. The data that had been collected was inventoried and classified and then analyzed using the deductive method to draw conclusions. The results of this study indicate that fulfilling the livelihood rights of children of divorce victims in Lombok, West Nusa Tenggara, Indonesia is not very effective. Research data shows that 45% of children who are the victims of divorce are not given a living right at all, and the remaining 55% are given a living but not by the nominal needs of the children, 24% of children are given a living of 100,000-300,000 thousand per month and 31% of children who are the victims of divorce are given a living of 350,000 -500,000 thousand rupiahs. Factors inhibiting the fulfillment of children's livelihood and education rights are 42% due to negligence, 26% due to marriage, 21% family conflict, and 11% due to economic factors. An alternative solution to overcoming the problem of fulfilling children's livelihood rights is socialization law, tabayyun and deliberation, religious approach, and legal approach.
Analysis of Policies and Strategies to Lower Childhood Stunting in South Sulawesi, Indonesia
Authors: Paikah Nur , Yamin Muhammad , Hafni Nur
Published: August 2024

Analysis of policies and strategies to accelerate stunting reducing in children in South Sulawesi Province. Examine the facts and make corrections to various policies and strategic programs that are better and more comprehensive by the central government and regional governments because the quality of future human resources is largely determined by the current condition of children so that the golden generation of 2045 can be realized. This research aims to analyzing policies to reduce stunting rates in South Sulawesi Province. The research uses normative legal methods analyzed with policy theory, while data collection techniques come from trusted sources such as government reports, scientific journals and health survey data. The research findings reveal several important factors contributing to the high stunting rates in South Sulawesi Province, including limited access to adequate nutrition, low maternal education levels, and poor sanitation. Evaluation of existing policies indicates that the policies implemented by the provincial government have had a positive impact but still require improvement and enhancement in their implementation. Therefore, recommended strategies to accelerate stunting reduction include improving access to adequate nutrition, enhancing maternal health education, and improving sanitation. The results of this study are expected to provide input to the provincial government and relevant stakeholders in formulating more effective and efficient policies to address stunting in children in South Sulawesi Province.
Judges' Considerations in Granting Marriage Dispensation Licenses in Indonesia: Islamic Family Law Perspective
Authors: Rohmadi Rohmadi , Ali Zezen Zainul , Apriani Fajar , Octavianne Helena , Permata Cindera
Published: August 2024

Setelah diamandemen, UU Perkawinan mensyaratkan adanya keadaan mendesak untuk memperoleh dispensasi nikah dari pengadilan. Namun dalam hal ini Undang-Undang tidak menjelaskan secara rinci kriteria-kriteria yang dianggap mendesak sehingga hakim sebagai orang yang mengetahui hukum (Ius Curia Novit) bertugas menafsirkannya dengan ijtihad. Tujuan penelitian ini adalah untuk mengetahui ijtihad hakim dalam menafsirkan Pasal 7 ayat 2 UU Perkawinan No. 16 Tahun 2019 dan mengetahui metode yang digunakan hakim dalam memutus perkara dispensasi nikah. Pendekatan yang digunakan untuk menganalisis permasalahan ini adalah pendekatan yuridis empiris. Pendekatan yuridis digunakan untuk mengkaji pasal-pasal peraturan-undangan yang mengatur tentang dispensasi nikah yaitu Undang-undang Nomor 1 Tahun 1974. Kemudian digunakan pendekatan empiris untuk mengungkap urgensi perkara dispensasi nikah menurut hakim pengadilan. Hasil penelitiannya hakim menafsirkan situasi yang mendesak dengan penafsiran yang sistematis, yaitu dengan kaidah dan norma hukum baik agama maupun negara berdasarkan teori penafsiran hukum. Selanjutnya dalam memutus perkara dispensasi nikah, hakim menggunakan metode kajian hukum Islam Istihsan dengan berpindah dari Kulliyah ke Juz'iyyah.
The Granting of Family Card for Siri Marriage in Banda City: Perspective of Islamic Family Law
Authors: Daniela Nadya Pratiwi , Hanapi Agustin , Husnul Muhammad , Fahri Marjana
Published: August 2024

Law No. 1 of 1974, as does the Compilation of Islamic Law, concerning marriage mandates the registration of every marriage to obtain legal validity such as a marriage certificate, which later becomes a requirement for making a family card. A family card is obtained if a marriage is registered in accordance with applicable laws and regulations. Siri (i.e., unregistered) marriage previously had various consequences, including children not having birth certificates, not having family cards, and, not being able to obtain their rights as husband and wife in the event of marital disputes. Therefore, marriage must be officially registered in order to obtain all the documents needed to create a family card. This will minimize the prevalence of siri marriage. However, the issuance of Minister of Home Affairs Regulation (PERMENDAGRI) No. 108 of 2019, which adds the status of unregistered marriage and unregistered divorce to the provision of family card, has allowed the registration of a family card without attaching a marriage certificate and accommodated providing family cards for unregistered marriages. On the one hand, having family cards is deemed necessary; yet, on the other hand, it is contrary to Law No. 1 of 1974 on Marriage. From a sociological point of view, it can have a negative impact on the increase of siri marriage as it no longer has any consequence at all. Thus, it is important to review the application of PERMENDAGRI No. 108 of 2019 sociologically from the perspective of Islamic family law using the theory of maslahah (benefit). This empirical study used the descriptive qualitative approach, which took place in Banda Aceh City. The study collected legal materials through document study. Sociologically, many negative effects have occurred on the issuance of family cards from the perspective of Islamic family law as well as the consequences of the implementation of PERMENDAGRI No. 108 of 2019 for women and children.
Participation of Meshchera service Tatars in the embassy service of the Russian state in the 16th–17th centuries (some aspects)
Authors: Belyakov Andrey Vasilyevich
Published: August 2024

It is known from sources and research literature that in the second half of the 16th–17th centuries, a significant number of interpreters and translators of the Tatar language, who were landowners from the Meshchera region, served in the Ambassadorial Prikaz (Office). However, their origin has not yet been analyzed in more detail. Based on previously obtained data, the author established that the translators were descendants of noble Siberian immigrants from the inner circle of Kuchum and the Kuchumovichs, as well as representatives of the most noble Meshchera princely families. All of them, through marriages, were in kinship and property to each other and provided protection when appointed to serve as employees of the Ambassadorial Office. The interpreters and villagers, apparently, for the most part came from ordinary Tatars. Their origin still remains unclear. At the turn of the 16th–17th centuries, their numbers increased at an explosive pace, but throughout the 17th century, for various reasons, a gradual decline in this category of employees of the Ambassadorial Office was recorded.
Fot citation: Belyakov A.V. Participation of Meshchera service Tatars in the embassy service of the Russian state in the 16th–17th centuries (some aspects). From History and Culture of Peoples of the Middle Volga Region. 2024, vol.14, no.1, pp.10–20. https://doi.org/10.22378/2410-0765.2024-14-1.10-20 (In Russian)
The new document from the reign of Mikhail Fedorovich about the service of the "newly-baptised people" and Tatars in the guard regiment
Authors: Belousov Maxim Rudolfovich
Published: August 2024

The article introduces into scientific circulation, investigates, and publishes a document on the history of noblemen and county servicemen of Likhvin, Solova, Borovsk, Vereya and Odoyev counties, "newly-baptised people" of Moscow, Borovsk, Maloyaroslavets, Serpukhov, Kaluga, Kolomna and Kashira counties and Tatar Cossacks of Borovsk county (the nominal list of the "noblemen of different counties who should serve in the guard regiment on Kropivna"). The nominal list studied in the article was deposited in the fund of the Military Records Office of the Russian State Archive of Ancient Acts (RGADA). The article gives an archaeographic description of the published document, and substantiates the proposed dating of the nominal list of military servicemen. The article describes the information potential of the nominal lists of service people. The article is addressed to specialists in social history, the genealogy of servicemen, including the "newly-baptised people" and Tatar Cossacks, and the source studies of clerical work documents.
For citation: Belousov M.R. The new document from the reign of Mikhail Fedorovich about the service of the "newly-baptised people" and Tatars in the guard regiment. From History and Culture of Peoples of the Middle Volga Region. 2024, vol.14, no.1, pp.145–163. https://doi.org/10.22378/2410-0765.2024-14-1.145-163 (In Russian)
Military and diplomatic service of the Astrakhan Yurt Tatars in the 17th–18th centuries
Authors: Toropitsyn Ilya Vasilyevich
Published: August 2024

The article examines the participation of Astrakhan Yurt Tatars in military campaigns waged by the Moscow state against external enemies, as well as examples of the use of Astrakhan murzas and herd heads to carry out various diplomatic assignments in the 17th–18th centuries. The research focuses on the wars with the Crimean Khanate and Turkey, Poland and Sweden, as well as individual military expeditions of the 17th–18th centuries undertaken by the tsarist authorities against the peoples of the North Caucasus and Central Asia. The article analyzes the mobilization potential of the Turkic service population of the Lower Volga region, the peculiarities of its involvement in wars, and its use in various military campaigns. Along with this, the facts of the involvement of the Astrakhan nobility in the performance of various diplomatic missions in relation to the peoples of the North Caucasus and Central Asia are being studied.
For citation: Toropitsyn I.V. Military and diplomatic service of the Astrakhan Yurt Tatars in the 17th–18th centuries. From History and Culture of Peoples of the Middle Volga Region. 2024, vol.14, no.1, pp.21–35. https://doi.org/10.22378/2410-0765.2024-14-1.21-35 (In Russian)
Subjects of the diplomatic activities of Tatar translators of the Orenburg Border Commission in Khiva (first half of the 19th century)
Authors: Sultangalieva Gulmira Salimzhanovna
Published: August 2024

The purpose of this article is to reveal individual stories of the inclusion of Tatar translators and interpreters of the Orenburg Border Commission in diplomatic activities in the Khiva Khanate. Due to their duty of service and knowledge of oriental languages, interpreter Mukhamet-Sharif Aitov, translators Iskender and Suleiman Batyrshin performed communicative functions between the embassies of the Khiva Khan in Orenburg and the regional administration and accompanied the Russian diplomatic missions to Khiva and the Khiva embassies to St. Petersburg. The result of their diplomatic activities was scientific information about the internal political and international situation of Khiva, which allowed the regional administration and the Center to develop action strategies and make certain decisions. The article is based on archival documents extracted from the funds of the central archives of Kazakhstan and Russia, and historical literature.
For citation: Sultangalieva G.S. Subjects of the diplomatic activities of Tatar translators of the Orenburg Border Commission in Khiva (first half of the 19th century). From History and Culture of Peoples of the Middle Volga Region. 2024, vol.14, no.1, pp.94–108. https://doi.org/10.22378/2410-0765.2024-14-1.94-108 (In Russian)
In Memory of Mirkasym Abdulakhatovich Usmanov (1934–2010) (on the 90th anniversary of his birth)
Authors: Khamidullin Bulat Lironovich
Published: August 2024

The article contains information about the life and work of an outstanding orientalist scientist, a talented teacher and writer, Doctor of Historical Sciences, professor, full member of the Academy of Sciences of the Republic of Tatarstan and the Archaeological Commission of the Russian Academy of Sciences, member of the Union of Writers of the USSR and the Tatar PEN Center, widely known public figure Mirkasym Abdulakhatovich Usmanov (1934–2010). The main milestones of his life and creative path are reproduced, the results of his scientific research are characterized, his contribution to the study and development of source studies and historiography of the history of the Tatar people and Tatarstan is indicated. Particular attention is paid to the research of M.A. Usmanov on source studies of the history of the Golden Horde.
For citation: Khamidullin B.L. In Memory of Mirkasym Abdulakhatovich Usmanov (1934–2010) (on the 90th anniversary of his birth). From History and Culture of Peoples of the Middle Volga Region. 2024, vol.14, no.2, pp.154–167. https://doi.org/10.22378/2410-0765.2024-14-2.154-167 (In Russian)
Leptin activation of dorsal raphe neurons inhibits feeding behavior
Authors: David Maxwell Nicholas , Elizabeth Smiley Cora , Tereza Sadek Alia , Zoe Loyo-Rosado Frances , Christian Giles Daniel , Alice Macht Victoria , Lynn Woodruff Jennifer , Lee Taylor Donzelle , Marie Glass Victoria , Peter Wilson Steven , Patrick Reagan Lawrence , Robert Fadel James , Alejandra Grillo Claudia
Published: August 2024

Abstract

Leptin is a homeostatic regulatory element that signals the presence of adipocyte energy stores, reduces food intake, and increases energy expenditure. Similarly, serotonin (5-HT), a signaling molecule found in both the central and peripheral nervous systems, also controls food intake. Using neuronal tract-tracing, pharmacological and optogenetics approaches, and in vivo microdialysis, combined with behavioral endpoints, we tested the hypothesis that leptin controls food intake not only by activating hypothalamic leptin receptors (LepRs), but also through activation of LepRs expressed by serotonergic raphe neurons that send projections to the arcuate (ARC). We show that microinjection of leptin directly into the dorsal raphe nucleus (DRN) reduces food intake in rats. This effect is mediated by LepR expressing neurons in the DRN as selective optogenetic activation of these neurons at either their DRN cell bodies or their ARC terminals reduces food intake. Anatomically, we identified a unique population of serotonergic raphe neurons expressing LepRs that send projections to the ARC. Finally, by utilizing in vivo microdialysis, we show that leptin administration to the DRN increases 5-HT efflux into the ARC, and specific antagonism of the 5-HT2C receptors in the ARC diminishes the leptin anorectic effect. Overall, this study identifies a novel circuit for leptin-mediated control of food intake through a DRN-ARC pathway, identifying a new level of interaction between leptin and serotonin to control food intake. Characterization of this new pathway creates opportunities for understanding how the brain controls eating behavior, as well as opens alternative routes for the treatment of eating disorders.

Article Highlights

· Half of serotonergic neurons in the dorsal raphe nucleus express leptin receptor mRNA.

· Activation of these raphe neurons expressing leptin receptors has an anorectic effect.

· Optogenetic activation of the arcuate terminals of these raphe neurons decreases food intake.

· Leptin administration directly to the dorsal raphe nucleus increases serotonin efflux in the arcuate. Blockade of the serotonergic receptors in the arcuate attenuates the anorectic effect of leptin injected into the raphe.
The Disease Burdens of Self-diagnosed Hidradenitis Suppurativa Patients in Japan: A Cross-sectional Web-based Survey
Authors: Hayama Koremasa , Okazaki Masateru , Akiyama Takeshi , Morita Kazuo , Nomura Toshifumi
Published: August 2024

Abstract is missing (Short communication)
MOTIVAÇÕES PARA A ESCOLHA DA PROFISSÃO DE ENFERMAGEM NA PERSPECTIVA DO ENFERMEIRO FORMADO
Authors: Sanematsu Laudelino Siqueira Amaral , Fernandes Maria do Carmo , Silva Ana Paula Jesus da
Published: August 2024

Objetivo: Analisar, avaliar e compreender as motivações da escolha da profissão de enfermagem na perspectiva do enfermeiro formado, com uma amostra nacional. Método: adotou-se o tipo de estudo exploratório, descritivo, qualitativo, e as respostas foram analisadas com base no referencial metodológico da análise de conteúdo. A amostra foi composta por 90 enfermeiros com alta formação (mestrado e doutorado) e residentes nas cinco regiões do país com vistas à aproximação da generalização. Resultados: do trabalho realizado emergiram três grandes categorias à luz das literaturas seminal e corrente, sendo elas, Convocação Transcendental, Sentido e Significado no Trabalho e Orientação Prossocial (altruísmo). A primeira categoria é uma motivação causada por um agente externo (Deus, por exemplo). Já a segunda e a terceira categorias dependem exclusivamente da motivação intrínseca. Ressalta-se que as três dimensões são conceituadas como promotoras de um senso de propósito e significado. Considerações finais: evidenciou-se que a enfermagem tem suas raízes como uma profissão vocacionada. Chamamos a atenção para o lado positivo e também o obscuro em se ter uma vocação e experimentá-la, pois, profissionais vocacionados podem não perceber o workaholismo, esgotamento físico-emocional e potencial exploração no local de trabalho.
Pembaharuan Sistem Pendidikan Di Pondok Pesantren Nurul Yaqin Ringan-Ringan
Authors: Putri Meilisa , Rivauzi Ahmad
Published: August 2024

This study aims to look at the renewal of the Education System which consists of curriculum, educators and students at the Nurul Yaqin Ringan-ringan Islamic Boarding School. This study uses a qualitative method with a descriptive approach. Sources of data were taken through direct interviews with informants consisting of the Caliph, Pondok Leaders, Deputy Curriculum of the Pondok, Daily Management of the El Imraniyah Islamic Development Foundation and Islamic boarding school educators Nurul Yaqin Light-ringan. To strengthen the data the researchers also collected data through observation and documentation. Overall the results of the study found that, First, the Education Curriculum at the Nurul Yaqin Mil-ringan Islamic Boarding School did not experience renewal in terms of learning books and congregations, but in terms of general education underwent several changes, Second, the renewal of Educators in book learning at the Nurul Yaqin Ringan-Ringan Islamic boarding is strengthened by coaching once a month. The three students experienced renewal in terms of promotion and selection of new students, and made an agenda for santri activities that was more filled with activities of memorizing the Qur'an and the coaching of tahsin of the Qur'an for students.
Kompetensi Guru Pendidikan Agama Islam Perspektif Imam An-Nawawi Dalam Kitab Al-Tibyan Fii Adaabi Hamalatil Quran
Authors: Fauzi Ahmad
Published: August 2024

This research is motivated by the emergence of problems that occur in the world of education, especially in terms of low competence and teachers' lack of attention to their obligations in educating. The deviations that occur have even reached a fatal level, starting from slapping, harassment, and even being tortured to death. So the solution is to re-study and refer to the books of the ulama, because they are the role models in this life, one of which is in the world of education. One book that can be used as a reference is the book at-Tibyan Fii Adaabi Hamaltil Quran written by Imam An-Nawawi. This research aims to explore Imam An-Nawawi's thoughts regarding the competency of PAI teachers in the At-Tibyan book and its relevance to today's education. This research uses qualitative methods with a type of literary study approach obtained from various literature such as journals, books and relevant scientific works, in analyzing data using content analysis techniques. The main data for this research is the book at-Tibyan Fii Adaabi Hamalatil Quranwritten by Imam An-Nawawi. The results of this research indicate that there is a suitability of Imam An-nawawi's thoughts in the At-Tibyan book with current contemporary education. This means that it is relevant to the Regulation of the Minister of Religion of the Republic of Indonesia Number 16 of 2010 concerning the Management of Religious Education in Schools.
CELL AND TISSUE DYNAMICS OF THE FOCUS OF CHRONIC CARRAGEENAN INFLAMMATION WITH THROMBIN INHIBITOR ADMINISTRATION
Authors: Pavlova Олена , Shevchenko Vladyslav
Published: August 2024

Chronic inﬂ ammation is an essential part of the development of various diseases, such as digestive disorders, heart disease, autoimmune diseases, cancer, diabetes, or neurodegenerative disorders. The role of cytokines and chemokines is to attract additional immune cells to the site of infection, including circulating neutrophils, which enhance microbial destruction through the production of interferon, proteases and reactive oxygen species. Elimination of the foreign/endogenous phlogogen and reprogramming of eﬀ ector cells to eﬀ ectively stop the production of inﬂ ammatory mediators leads to the resolution of inﬂ ammation and return to homeostasis.The aim of the study was to determine the cell and tissue dynamics of the focus of secondary chronic carrageenan inflammation after thrombin inhibitor administration.Material and methods. The experimental study was conducted on 72 adult male WAG laboratory rats. The model of inﬂ ammation was secondary chronic aseptic inﬂ ammation induced by intramuscular injection of 10 mg of λ-carrageenan (Sigma, USA) dissolved in 1 ml of isotonic sodium chloride solution into the right thigh area. Dabigatran etexilate was administered intragastrically through a gavage tube at a dose of 15 mg/ kg/ day dissolved in 1 ml of isotonic sodium chloride solution daily throughout the experiment. The cell and tissue dynamics of the focus of secondary chronic carrageenan inﬂ ammation were studied on days 1, 7, 14, 21, and 28 of the experiment.Morphological examination of muscle tissue samples showed that both in the natural course of secondary chronic carrageenan inﬂ ammation and in secondary chronic carrageenan inﬂ ammation with dabigatran etexilate administration, an inﬂ ammatory process with a predominance of proliferative processes develops, which is typical for chronic inﬂ ammation.Morphological changes in both experimental groups are similar, but with a certain diﬀ erence in the intensity of the process and the timing of development. Thus, the purulent- necrotic process in the natural course of secondary chronic carrageenan inﬂ ammation was detected on day 7 and its intensity can be deﬁ ned as moderate, while in secondary chronic carrageenan inﬂ ammation with dabigatran etexilate administration, a signiﬁ cantly pronounced purulent- necrotic (mainly purulent) process was detected on day 14. But already on day 21 of attenuation and healing of the inﬂ ammatory process in the form of proliferation and organization, these processes occurred with greater intensity in the group of rats with secondary chronic carrageenan inﬂ ammation with dabigatran etexilate administration, which is manifested by an increase in the number of macrophages, ﬁ broblastic cells, and increased collagen formation compared with the natural course of inﬂammation.
Efek Kombinasi Ekstrak Temulawak dan Belimbing Wuluh terhadap Perbaikan Histologis Ginjal Tikus yang Terpapar Herbisida Paraquat
Authors: Alipin Kartiawati , Ratningsih Nining , Nurjihan Salsabila
Published: August 2024

Paraquat merupakan herbisida yang digunakan pada pertanian. Akumulasi paraquat pada tanaman sayur jika dikonsumsi dapat bersifat racun dan menyebabkan gangguan pada organ ginjal seperti kerusakan pada glomerulus berupa edema spatium Bowman, serta pada tubulus berupa infiltrasi sel radang dan pembengkakan sel epitel tubulus. Tujuan penelitian ini yaitu untuk mengetahui pengaruh pemberian kombinasi ekstrak temulawak dan belimbing wuluh (TBW) terhadap perbaikan histologis ginjal tikus yang terpapar paraquat. Metode penelitian secara eksperimental menggunakan Rancangan Acak Lengkap dengan lima perlakuan dan lima ulangan. Induksi paraquat dilakukan pada seluruh perlakuan kecuali KN. Susunan perlakuan yang terdiri dari KN (tween 80 1%), KP (paraquat 25 mg/KgBB), P1 (kombinasi TBW 770 mg/KgBB), P2 (kombinasi TBW 385 mg/KgBB), P3 (kombinasi TBW 192,5 mg/KgBB). Parameter yang diamati yaitu histologis ginjal meliputi diameter glomerulus, lebar ruang Bowman, dan persentase nekrosis pada tubulus proksimal. Data dianalisis secara statistik menggunakan uji ANOVA pada taraf kepercayaan 95% kemudian dilanjutkan dengan uji jarak berganda Duncan. Hasil penelitian menunjukkan terdapat peningkatan diameter glomerulus, penurunan lebar ruang Bowman serta penurunan persentase nekrosis sel tubulus proksimal pada perlakuan P1-P3 dengan dosis optimum yang dapat memperbaiki struktur histologis ginjal yaitu 385 mg/KgBB. Kesimpulan penelitian ini yaitu kombinasi ekstrak temulawak dan belimbing wuluh berpengaruh memperbaiki struktur histologis ginjal tikus yang terpapar paraquat.
Preferensi dan Variasi Pakan Echinodermata (Ophiocoma dentata dan Holothuria atra) terhadap Lamun dan Makroalga
Authors: Pribadi Tri Dewi Kusumaningrum , Ramadhani Vessa , Alipin Kartiawati
Published: August 2024

Echinodermata memiliki peran penting dalam ekosistem pesisir, khususnya ekosistem padang lamun karena membantu proses penguraian serasah pada kolom sedimen. Studi ini bertujuan untuk mendeskripsikan preferensi dan variasi pakan dari Echinodermata terhadap lamun dan makroalga, dengan menggunakan hewan uji dari spesies Ophiocoma dentata dan Holothuria atra. Bahan pakan yang disediakan adalah lamun (Thalassia hemprichii) dan makroalga (Padina australis, Sargassum sp., dan Ulva lactuca). Studi ini bersifat eksperimental berdurasi 72 jam, yang dilakukan pada suhu ruang dengan siklus pencahayaan alami. Pengamatan berat basah pakan sebelum dan sesudah eksperimen dilakukan dengan menimbang berat awal dan akhir pakan yang diberikan kepada hewan uji. Analisis isi perut dilakukan untuk melihat variasi pakan hewan uji dengan melakukan pembedahan organ pencernaan hewan uji. Nilai SDR menunjukkan bahwa pakan yang dominan dimakan oleh O. dentata dan H. atra adalah lamun (T. hemprichii). Studi mengenai preferensi dan variasi pakan memberikan informasi penting dalam menjaga siklus makan-memakan di ekosistem padang lamun sebagai salah satu upaya konservasi.
MARGA Callisia Loefl. (COMMELINACEAE): TAMBAHAN UNTUK FLORA JAWA
Authors: Irsyam Arifin Surya Dwipa , Hariri Muhammad Rifqi , Peniwidiyanti Peniwidiyanti , Irwanto Rina Ratnasih
Published: August 2024

Callisia Loefl. merupakan marga tumbuhan asing dengan distribusi asal dari Amerika tropis yang untuk pertama kalinya ditemukan di Jawa. Marga tersebut ditemukan di Desa Cikeruh dan Sayang, Kecamatan Jatinangor, Kabupaten Sumedang, Jawa Barat. Callisia diwakili oleh dua jenis tanaman hias, yaitu C. fragrans (Lindl.) Woodson dan C. repens (Jacq.) L. Namun, jenis yang terakhir juga telah lolos dari kultivasi dan tumbuh pada celah antar bebatuan di Desa Sayang, Jatinangor. Callisia fragrans dicirikan oleh perawakan terna yang kokoh seperti perdu, stolon yang panjang, susunan daun spiral, helaian daun melanset-melonjong, dan tepi daun mengombak. Sementara itu, Callisia repens berupa terna dengan susunan daun berderet dua, helaian daun membundar telur melebar hingga membundar, permukaan adaksial daun berwarna hijau atau dengan bercakbercak ungu, dan permukaan abaksial daun berwarna ungu. Deskripsi, foto, dan diskusi singkat disajikan sebagai berikut. Kunci determinasi untuk puak Tradescantieae di Jawa juga disediakan secara lengkap pada artikel ini.
Implementation of Digital Transformation and Government Enterprise Architecture in Improving the Performance of Integrated Social Services
Authors: Ekarini Mira Indriyulia , Rahayu Agus , Disman Disman , Wibowo Lili Adi
Published: August 2024

This study addresses the subject matter of declining public confidence in local governments in Indonesia, primarily due to issues in public service delivery, highlighting the urgent need for improved integrated social services. The objective is to analyze the mediating effect of enterprise architecture orientation on the influence of environmental turbulence, flexibility strategy, business model innovation, and digital transformation on social service performance in West Java. Methods involved a survey explanatory approach with all 27 social service providers in West Java Province, employing whole population sampling. Data were analyzed using descriptive statistical analysis and hypothesis testing using Partial Least Square Structural Equation Modeling (PLS-SEM). Results indicate that environmental turbulence, flexibility strategy, business model innovation, and digital transformation significantly impact social service performance when mediated by enterprise architecture orientation. The conclusions suggest that a robust model emphasizing strategic architectural orientation and effective implementation of flexibility, innovation, and digital transformation can enhance social service performance amidst environmental challenges. This study contributes to understanding the complex dynamics of social service provision in local governments, advocating for strategic investments in enterprise architecture and adaptive strategies to improve public service delivery and restore public trust.
Due to the COVID-19 pandemic: Maintaining economic growth by conducting catastrophic policy without considering adaptive structuration and foresight orientation
Authors: Sumiyana Sumiyana
Published: August 2024

When COVID-19 hit all the Asian countries, Indonesia issued various laws and regulations. This study investigates these laws that do not improve the country’s ability to increase its adaptive structuration and foresight-oriented investment. It analyzes all the new laws, which should be based on the requirements of both concepts. It considers that all the laws are intended to defend the Government of Indonesia’s economic performance (GoI). It means that all the established regulations were built on the premise that they only focused on national economic preservation, especially economic growth. In other words, this study stated that the absence of regulations containing adaptive restructuration and foresight-oriented investment would decrease the state’s agility. This absence potentially impacts Indonesia to zcategorize the future as the state’s political failure. It shows evidence that Indonesia could not enforce and empower its structural potential. This study indicates that Indonesia made no foresight-oriented investment to cover the disbursed costs due to the COVID-19 pandemic. Future policies should be improved by including growth opportunities to enhance Indonesia’s agility. This agility could finally be achieved when all the laws issued by the GoI do not contain the praxis.
Wpływ zróżnicowanej rozstawy rzędów i ilości wysiewu na rozwój i plonowanie soi (Glycine max (L.) Merrill). Cz. III. Ekonomiczne aspekty produkcji nasion
Authors: Gniadzik-Zasańska Małgorzata , Kozak Marcin , Wondołowska-Grabowska Anna
Published: August 2024

W Polsce produkcja nasion soi ulega znacznym wahaniom w latach ze względu na niestabilność plonowania oraz zmienną opłacalność prowadzenia uprawy. Celem podjętych badań było określenie opłacalności produkcji nasion soi (Glycine max (L.) Merrill) pod wpływem zróżnicowanej rozstawy rzędów oraz wzrastającej liczby wysianych nasion na 1 m2. Analizę opłacalności przeprowadzono na podstawie wyników badań pochodzących z doświadczeń polowych przeprowadzonych w latach 2015–2017 na polach doświadczalnych Instytutu Agroekologii i Produkcji Roślinnej Uniwersytetu Przyrodniczego we Wrocławiu. Doświadczenia polowe założono w układzie split-plot, w czterech powtórzeniach, z dwoma czynnikami zmiennym: zróżnicowaną rozstawą rzędów (15 cm, 30 cm), zróżnicowaną liczbą wysiewanych nasion (50, 75, 90 nasion na 1 m2). Badania własne wykazały, że koszty bezpośrednie poniesione na uprawę soi na nasiona były kształtowane przez zróżnicowaną liczbę wysiewanych nasion na 1 m2, natomiast nie zależały od zastosowanej rozstawy rzędów. W strukturze kosztów bezpośrednich największy udział miał łączny koszt zabiegów uprawowych i koszt zakupu materiału siewnego uzależniony od zmiennej liczby wysiewanych nasion na jednostkę powierzchni.
Assessment of the ecological state of surface waters of the Luga River, in the town of Volodymyr, by macrophytes
Authors: Tsos Oksana , Radzii Volodymyr , Kocun Larisa , Sukhomlin Kateryna , Melnyk Oleksandr
Published: August 2024

The objectives of our research were an ecological assessment of the quality of the Luga River water in the town of Volodymyr (Volyn region, Ukraine) by physico-chemical and phyto-indicative parameters, analysis of the species composition of the flora of aquatic and coastal aquatic plants by ecotypes, identification of protected species and indicator species. The studies were made during the 2022–2023 growing season at four test sites within the town of Volodymyr. According to the results of field floristic studies of selected test sections of the Luga River in Volodymyr, 25 species of aquatic and coastal-aquatic plants were found, belonging to the division of Magnoliophyta, two classes (Magnoliopsida and Liliopsida), and include sixteen families and twenty-two genera. The most represented class Liliopsida includes 16 species (64%) belonging to 13 genera and 8 families. The class Magnoliopsida consists of 9 species belonging to 9 genera and 8 families.
During the research, 13 types of macrophyte indicators were found at test site no. 1 (Old Cathedral), 19 indicator species at test site no. 2 (Hydrological station), eight species at test site no. 3 (Lyceum boarding school), and eight species on site no. 4 (Shistivsky Bridge).
The Macrophyte Index for Rivers (MIR) of the Luga River in the town of Volodymyr varies generally from 30.75 to 36.71, which corresponds to water quality Class III, satisfactory ecological condition; except at test site no. 2 where water quality is class II, good ecological condition.
The influence of fatigue on the daily functioning of multiple sclerosis patients
Authors: Arsovski Denis
Published: August 2024

Introduction

Fatigue is a complex and often debilitating symptom of multiple sclerosis (MS), affecting a large number of individuals with the condition. Research has shown that fatigue and impaired mobility are the two main causes of work loss in people with MS, with fatigue being one of the leading causes of unemployment.

Aim

The research aimed to study the impact of fatigue on individuals with MS, including its effects on physical functioning, daily life activities, work, family, and social life.

Material and method

The data was collected using the Fatigue Assessment Scale, a tool specifically designed for individuals with multiple sclerosis to assess the impact of fatigue on their work, home, and school life. The Fatigue Severity Scale measures fatigue levels, which distinguishes fatigue from clinical depression due to overlapping symptoms. Approximately 700 participants from all over the world participated in the study, with the majority coming from the USA, Canada, and Germany.

Results

The results indicate that fatigue presents a significant challenge for individuals with MS, impacting activities of daily life including leisure, work, and treatment (kinesitherapy). The results also show a connection between gender and fatigue, although the dependence or independence between the two was not determined. Our findings suggest that fatigue is one of the three symptoms that causes significant difficulties for people with MS, affecting all areas of their functionality.

Conclusions

In conclusion, this scientific paper highlights the importance of addressing fatigue in individuals with MS, as it can have a significant impact on their quality of life. Effective management strategies are essential to ensure the health, well-being, and recovery of affected SM patients. Further research is needed to understand the various causes of fatigue in MS and to develop effective interventions to address it.