bluuebunny/crossref_metadata_2025 huggingface dataset:
Parents’ report on the health care management of spina bifida in early childhood
Authors: Ong Katherine S. , Reeder Matthew , Alriksson-Schmidt Ann I. , Rice Sydney , Feldkamp Marcia L.
Published: December 2022

PURPOSE: This study aimed to describe health care use by type of health providers and care settings visited by children with spina bifida (SB) and to compare this use between children with and without a shunt. METHODS: Health care use data were extracted from a larger study on the health and functioning of children with SB aged 3–6 years. The present study focused on the medical information subsection of a parent-reported survey related to SB care, general care, specialty care (e.g., neurosurgery), emergency care, and complications related to SB and shunts. RESULTS: Parents of 101 children with SB participated. Most of the children were male with myelomeningocele and had a shunt. They visited a health care provider for SB care an average of 7.4 times and a specialist an average of 11.9 times in the previous 12 months. Most visited a multidisciplinary clinic for SB-related care and a private physician’s office for general care. Children with a shunt had more SB-related medical visits, more visits to a specialist, and a greater number of different types of specialists than those without it. Frequency of emergency room visits did not differ between the two groups. Health providers informed parents about headaches, vomiting, and fever as signs of complications, and some parents did report shunt-related complications. CONCLUSION: SB is a complex medical condition requiring that children receive medical care from various medical specialists, especially for children with a shunt. Findings on health care use suggest high levels of monitoring and care coordination that parents navigate to care for their child.
Analytical illustration of occupational injuries between 2019 and 2020 in the Kingdom of Saudi Arabia
Authors: Alangari Hessa M. , Alrashed Abeer M.
Published: December 2022

BACKGROUND: In recent times, Saudi Arabia has experienced growing industrialisation and more opportunities for business requires more human capital if it is to become one of the largest economies in the world and such growth brings with it some health issues. OBJECTIVE: The study aimed to provide analytical illustration of occupational injuries among the workforce in Saudi Arabia. To accomplish the study purpose, four measurements were carried out, the occurrence of occupational injuries, the severity of occupational injuries, the patterns in occupational injuries, and the occupational injuries in relation to the demography of the injured employees. METHODS: A retrospective study was designed based on a secondary data of occupational injuries (OI) that was obtained from the General Organization for Social Insurance. Descriptive analysis was used to describe the occurrence and the outcome of OI. Multivariate regression was applied to the patterns in OI and to those injuries in relation to the demography of the injured employees. RESULTS: Within two years, Riyadh Province had the highest occurrence of OI (30.6%). Construction and Elementary occupations had the highest occurrence of OI (36.3% and 45.7% respectively). Injuries’ occurrence differed significantly between months. Fridays significantly associated with low injuries. Among demography, injuries differed significantly in relation to the employees’ age. CONCLUSIONS: There was no noticeable decrease in death cases from an earlier local study while they were less compared to other nations (Turkey and South Korea). Compared to other nation, Islamic holidays that are characterized by heat waves were not associated with increased OI. Preventive measures are insufficient.
The use of complex drugs in the treatment of vascular disorders of various origins
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Solovyova E.Yu. , Abdullaev Sh.P. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
Published: December 2022

One of the most important places in the pathogenetic therapy of various vascular disorders is occupied by angioprotective, venotonic, antiplatelet, and antithrombotic therapy. In this regard, drugs with a complex effect on various links of vascular disorders are of particular interest. These drugs include AngioNorm®. It is a dry extract obtained from a mixture of medicinal plant raw materials: horse chestnut seeds, licorice roots, hawthorn and rosehip fruits. The combined composition characteristics of the drug extract determine a wide range of its pharmacological activity. The pharmacological properties of the drug, determined by the extract composition, have been confirmed in experimental preclinical and clinical studies which have demonstrated good efficacy, safety and tolerability of therapy in patients with various vascular and microcirculatory disorders (eg. chronic venous insufficiency, hypertension, coronary heart disease, cerebrovascular disease, hemorrhoids, trophic ulcers in the setting of varicose veins, post-infarction conditions, upper limb lymphoedema). The results of clinical studies indicate the possibility of long-term and safe use of this drug in the complex therapy of various vascular lesions in outpatient and inpatient settings KEYWORDS: chronic venous diseases, cardiovascular diseases, microcirculation disorders, angioprotectors, antiplatelet agents, Angionorm. FOR CITATION: Solovyova E.Yu., Abdullaev Sh.P. The use of complex drugs in the treatment of vascular disorders of various origins. Russian Medical Inquiry. 2022;6(8):443–450 (in Russ.). DOI: 10.32364/2587-6821-2022-6-8-443-450.
Autologous hematopoietic stem cell transplantation for the treatment of active ankylosing spondylitis (clinical case)
Authors:   V.A. Almazov National Medical Research Center, St. Petersburg, Russian Federation, Benevolenskaya S.S. , Maslyansky A.L. ,   V.A. Almazov National Medical Research Center, St. Petersburg, Russian Federation, Chudinov A.L. ,   Clinical Rheumatological Hospital No. 25, St. Petersburg, Russian Federation, Gaydukova I.Z. ,   Clinical Rheumatological Hospital No. 25, St. Petersburg, Russian Federation,   I.I. Mechnikov North-Western State Medical University, St. Petersburg, Russian Federation, Mazurov V.I. ,   Clinical Rheumatological Hospital No. 25, St. Petersburg, Russian Federation,   I.I. Mechnikov North-Western State Medical University, St. Petersburg, Russian Federation
Published: December 2022

Nowadays, patients with ankylosing spondylitis (AS) receive drugs for an indefinite period of time, which determines the need to search for new types of treatment that can induce medium- and long-term drug-free remission. Some authors consider the possibility of autologous hematopoietic stem cell transplantation (aHSCT) in combination with high-dose chemotherapy as such methods of treatment. The evidence base on the efficacy and safety of aHSCT in AS is represented by single cases, one of which we are currently presenting. The article presents the results of a seven-year clinical follow-up concerning a male patient with severe AS who underwent aHSCT, which led to the achievement of short-term remission with subsequent disease exacerbation. Due to the high activity of AS and zero treatment result, it was decided to initiate treatment with the interleukin 17A (IL-17A) inhibitor, secukinumab. At the time of writing, the patient has been receiving secukinumab at a dose of 300 mg per month for 3 years. During the first year of treatment, there was a significant positive clinical and laboratory tendency in the form of a pain syndrome reduction, normalization of ESR and CRP levels, a decrease in the BASDAI index to 3.2 points, and the ASDAS index to 1.8 points. The authors conclude that aHSCT in combination with high-dose chemotherapy and subsequent administration of cyclosporine A in the presented case did not lead to persistent remission of AS, and the risk–benefit ratio for the patient is shifted towards risk. At the same time, treatment with IL-17A inhibitor in a standard dosage allowed to control the disease activity with a high safety profile for 3 years. KEYWORDS: ankylosing spondylitis, Bekhterev’s disease, radiographic axial spondyloarthritis, autologous hematopoietic stem cell transplantation, TNF-alpha inhibitors, IL-17A inhibitor, remission. FOR CITATION: Benevolenskaya S.S., Maslyansky A.L., Chudinov A.L. et al. Autologous hematopoietic stem cell transplantation for the treatment of active ankylosing spondylitis (clinical case). Russian Medical Inquiry. 2022;6(8):486–490 (in Russ.). DOI: 10.32364/2587- 6821-2022-6-8-486-490.
The Quantum Character of Perception: The Probabilistic and Reversible Thermodynamic Cycle can Produce Spin-like Attitudes, Thinking, and Behavior
Authors: Deli Eva
Published: December 2022

One of the most puzzling questions in neuroscience is the nature of emotions and their role in consciousness. The sensory system's energy/information exchange revolves around a stable resting state; therefore, perception represents a closed thermodynamic cycle and can be modeled via the reversible Carnot engine. The brain's significant energy investment in maintaining the resting state indicates its essential role as the ground state of consciousness, the source of our sense of self. Perception forms either an endothermic or exothermic cycle. The first represents high entropy resting state with irreversible activations, generating novelty and intellect; it is energetically analog to the fermionic up-spin. However, exothermic physical processes give rise to time's arrow and loss of work capacity; reversible low entropy activations lead to past focus, regret, and remorse. The energy-weak condition is the psychological spin-down state. The reversible thermodynamic cycle, a classical system, takes on quantum characteristics and gives rise to a psychological spin. The quantum and classical natures represent a particle-like duality between continuous and discrete states explained by the fermionic hypothesis. Therefore, emotions are the brain's homeostatic master regulators. They maintain particle-like stability manifested by cognitive comfort by utilizing physiological and hormonal regulation.
Acute Oral Toxicity Study of Indigofera Tinctoria L. Aqueous Extract, a Substitute for Synthetic Food Colorants: Fourier Transform Infrared Spectroscopy, Biochemical, and Histopathological Investigation
Authors:   Department of Biology, Faculty of Science, University of Jiroft, Jiroft, Iran., Ramzani Ghara Abdollah , Ezzati Ghadi Fereshteh ,   Department of Biology, Faculty of Science, University of Jiroft, Jiroft, Iran. ,, Mousaie Amir ,   Department of Biology, Faculty of Science, University of Jiroft, Jiroft, Iran. ,
Published: December 2022

Background and Purpose: This research aimed to investigate the in vivo acute oral toxicity of aqueous extract of Indigofera tinctoria L. in different doses in Wistar rats. Materials and Methods: Twenty-five male rats were divided into five groups (n=5 for each group). Group I served as the control, and the other four groups received I. tinctoria (100, 250, 500, and 1000mg/kg body weight) for 14 days. At the end of the experiment, all animals were killed, and the blood samples were collected for biochemical assay. The fourier transform infrared spectroscopy (FTIR), and histopathological analyses were done on different tissues. Results: According to the results, rats who received I. tinctoria (100mg) had lower triglyceride than the control group. Moreover, I. tinctoria administration in all groups did not change the serum glucose, creatinine, urea, and high-density lipoprotein amounts. In addition, using 100mg of the extract resulted in a lower alanine transaminase level than the control. Also, histopathology data indicated no signs of tissue toxicity and degeneration in all experimental groups. Furthermore, FTIR indicated that I. tinctoria had not changed the tissues’ protein structure. Conclusion: It can be concluded that I. tinctoria can be used as colorant food up to 1000mg/kg body weight.
DAMPAK COVID-19 TERHADAP TREN HARGA SAHAM PADA SEKTOR HEALTCARE DI INDONESIA
Authors: Rezky Amanda Tiara , Ahmar Nurmala
Published: December 2022

This study aims to see the impact of Covid-19 on stock price trends in the healthcaresector in Indonesia. This study uses an event study, which means the data used in thisstudy are financial market data to measure the impact of an event on company valuesuch as share prices of healthcare companies. on companies that have been listed onthe Index in the period July 2020 to June 2021 in a row. In common, there was apositive correction at the end of 2020 from August to December 2020. Meanwhile, in2021 at the beginning of the year, stock prices began to decline from January to April,in line with the condition of the impact of the pandemic experienced by Indonesia inthe second year. Until March to June 2021, the closing price at the end of the monthbegan to see a movement towards a positive correction, it is predicted that the nextmonth towards the end of the year will be the right time to invest, stock prices towardsthe end of the year will experience an increase in prices.
Pentingnya corporate social responsibility pada strategi perusahaan dalam masa resesi ekonomi
Authors: Stefhanie Stefhanie , Suhardjo Iwan
Published: December 2022

Previous study researching the relationship between corporate social responsibility (CSR) and corporate financial performance (CFP) shows how important industry specificity is. Seeing by the stakeholder theory, we argue that strategic fit of CSR has a multi-dimensional characteristics, some CSR activity will be more impactful for certain industry than the others. We tested two set of hypothesis including controversial and non-controversial industry. Furthermore, we do this research by using 2019 economic recession in Indonesia throughout Covid-19 as a boundaries condition. Our studies contributes to the literature and demonstrate the role of CSR by explaining the strategic fit of CSR to specific Industry. Additional testing with mechanism in time of economic hardship adds an aspect of uniqueness to our empirical contributions.
Analisis penerapan penyesuaian tarif pajak penghasilan badan dan prosedur pemindahbukuan
Authors: Sagita Melda , Sugiyanto Sugiyanto , Sumaryana Fitriana Dewi
Published: December 2022

Taxpayers often make mistakes in determining the tax burden that causes losses for the taxpayer. The purpose of this study is to determine the appropriate and beneficial tax provisions for cooperative business entities in determining the income tax payable. The data obtained is sourced from the Cooperative PHU Report for the Financial Years of 2020 and 2021. The analytical method used is descriptive qualitative analysis. The results of the study concluded that Cooperatives benefited more from using the Tariff of Government Regulation in Lieu of Law no. 1 of 2020, because the tax burden owed by the taxpayer is smaller than the calculation according to the Tariff Regulation Article 17 paragraph 2 letter a of Law no. 36 of 2008, with the results of the discussion and analysis, namely the Koperasi Serba Usaha Tandangsari, so far, in compliance with the cooperative, it has carried out the obligation to pay taxes. The Koperasi Serba Usaha Tandangsari should be able to adjust the applicable corporate income tax rate.
Respons pajak daerah: Impresi covid-19?
Authors: Ismiyanti Ismiyanti , Dewata Evada , Dwitayanti Yevi
Published: December 2022

The Covid-19 pandemic 2020 caused decrease Regional Tax Revenue in Palembang. The purpose of research to analyze comparison of Regional Tax receipts in Palembang before and during the Covid-19 and to analyze the comparison of Land and Building Tax receipts in 18 Districts in Palembang before and after the adjustment Tax Object Selling Value rate. The type research is descriptive quantitative with secondary data types use panel data with time series and cross section data types analyzed using Paired Sample T Test technique through the SPSS version 26 application. The total population is 120 consisting of 12 types regional taxes 2018-2021 period and Land and Urban Building Tax in 18 sub-districts 2017-2020 period. The sampling technique is saturated sampling so number of samples is 120. The results research are the types regional taxes affected by the Covid-19 are Parking and Hotel Tax. The sub-districts affected adjustment Tax Object Selling Value rate are 9 sub-districts, Sukarami, Ilir Timur I, Kalidoni, Ilir Timur II, Jakabaring, Kemuning, Ilir Timur III, Ilir Barat I, and Alang-Alang Lebar. The implications this research is can be informative suggestions in formulating regulations as a corrective step to increase local tax revenues in the city of Palembang.
Januari efek di Bursa Efek Indonesia, Bursa Efek Amerika, Bursa Efek Jerman, dan Bursa Efek Jepang sebelum, sesaat dan sesudah pandemi Covid-19
Authors: Ulfarizty Zahra Putri , Komariah Siti
Published: December 2022

Many factors can affect the movement of stock prices in the capital market. Investors can use these factors as a reference in making investment decisions. One of them is the Market Anomaly. Based on the existing anomalies, the seasonal anomaly is the most frequently studied anomaly seen from its effect on company stock returns. One of the categories of seasonal anomaly is the January Effect. This study aims to find out how the January effect phenomenon is on the Indonesian, American, German, and Japanese Stock Exchanges for the period 2019 - 2021. In addition to knowing whether there are differences in stock returns between January and other months, and to find out whether there are differences in stock returns on the stock exchange effects of Indonesia, America, Germany, and Japan during the study period. The data used is the weekly primary stock price index data for the period January 2019 to December 2021. The research method used is the comparative method and event study. While the analysis technique used is the normality test, homogeneity test, Anova test, and post hoc test. The results showed that there was no January effect on the Indonesian, American, German and Japanese stock exchanges because there was no significant difference in the average stock return value between January and other months.
Pengaruh kualitas produk dan harga terhadap keputusan pembelian di Toserba Borma Cikutra
Authors: Mawarnie Devy , Fahira Dinda Marsya
Published: December 2022

The era that is currently underway is driving changes in Indonesia, as well as the increase and development of the business world, which is increasingly rapid. With this comes the rise of the goods and services industry. Retail companies must know what the needs and expectations of consumers are in order to allow them to purchase a product. This study aims to analyze the effect of product quality and price on purchasing decisions. Borma is a department store that is quite large, cheap, and complete because the price is cheap and the goods are quite complete. So the purpose of this research is to know the effect of product quality and price on consumer purchasing decisions at the Borma Cikutra department store. The object of this study is consumers who have made purchases at the Borma Department Store, and the population is unknown. The method used in this study uses multiple linear regression analysis with the SPSS application to process the data. The data used is primary data collected via questionnaires, with samples drawn from 97 Borma department store customers. The results of this study indicate that product quality and price have a significant effect on purchasing decisions.
Linear Model Equation for Prediction and Evaluation of Surface Roughness of Plain-Woven Fabric
Authors: BEYENE Kura Alemayehu , MUHAMMED Nuredin
Published: December 2022

Nowadays, evaluating fabric touch can be a great interest of industries to match the quality needs of consumers and parameters for the manufacturing process. Modeling helps to determine how structural parameters of fabric affect the surface of a fabric and also identify the way they influence fabric properties. Moreover, it helps estimate and evaluates without the complexity and time-consuming experimental procedures. In this research paper, the linear regression model was developed that was utilized for the prediction and evaluation of surface roughness of plain-woven fabric. The model was developed based on nine different half-bleached plain-woven fabrics with three weft Yarn counts 42 tex, 29.5 tex & 14.76 tex, and three weft thread densities (18 picks per c, 21ppc & 24 picks per c) and then the surface roughness of plain-woven fabric was tested by using Kawabata (KES-FB4) testing instrument. The findings reveal that the effects of count and density on the roughness of plain-woven fabric were found statistically significant at the confidence interval of 95%. The weft yarn count has a positive correlation with surface roughness values of plain-woven fabrics. On the other hand, pick density has a negative correlation with the surface roughness values of plain-woven fabrics. The correlation between measured surface roughness by KES-FB4 and calculated surface roughness by the model equation show how they are strongly correlated at 95% (R² of 0.97).
Adaptive response of koi carp (Cyprinus carpio koi) to low and high temperatures in experimental conditions
Authors: Grynevych N. E. , Khomiak O. A. , Sliusarenko A. O. , Trofymchuk A. M. , Zharchynska V. S. , Osadcha Yu. V. , Tkachenko O. V.
Published: December 2022

Abiotic factors of the water environment are essential for the life of hydrobionts. They are determined by two main criteria – the intensity of the impact factor and the tolerance of each species. The work aims to substantiate the adaptive capabilities of this summer's koi carp (Cyprinus carpio koi) under the influence of low and high temperatures, to compare the coefficients and breathing rhythms of the research objects. Experimental research was carried out in the conditions of the aquarium-basin complex of the Department of Ichthyology and Zoology of the Bila Tserkva National Agrarian University. Two aquariums with a volume of 800 dm3 were used for the experiment. Individuals of approximately the same size and weight (25–30 g) were divided into two groups. The first group of fish was kept at a temperature of 11–14 °C for 30 days, and the second group was kept at a temperature of 24–29 °C for 30 days. During the experiment, there were 20 specimens in each aquarium. This summer koi carp (Cyprinus carpio koi). Feeding was carried out with Alltech Coppens Pre Grower feed – 15EF, 2.0 mm. Composition of ingredients (%) per 1 g of feed: raw protein – 50; fats – 15; fiber – 0.80; ash – 8.6; phosphorus – 1.21. In experimental conditions, changes in consumption of koi carp (Cyprinus carpio koi) O2, the release of CO2 and NH3 (per 1 g of live weight in 1 hour) at temperatures of 11–14 °С and 24–29 °С were studied. The consumption of O2 and the release of NH3 in these summers of koi carp at low and high temperatures were compared. The change in respiration (RR) and ammonia (N/O) coefficients in “warm” and “cold” fish with increasing temperature was analyzed. The breathing rhythm and oxygen per breath at different environmental temperatures were determined. Based on the obtained data, the adaptive reactions of this year's koi carp to the influence of reduced and increased temperature indicators of the aquatic environment were determined.
Behavior, decisions and ecological transition: experimental approaches with policy implications
Authors: Antonioni Alberto , Cabrales Antonio , Lipari Francesca , Sánchez Anxo
Published: December 2022

One key aspect of the ecological transition has to do with individuals’ and collective behavior and its impact on climate change and decarbonization. We will describe how these questions can be studied by proper experimental designs by focusing on two examples: the implementation of Nordhaus's climate club idea for making countries contribute to climate change mitigation, and the interplay between the perception of the risk of a climatic catastrophe and the social norms arising from, and influencing, individual behavior. We will draw conclusions of the outcome of the experiments that can be relevant for policy making.
Analisis Pengaruh Promosi, Life Style, dan Kualitas Produk Terhadap Impulse Buying Shopee di Kota Batam
Authors: Sihombing Dika Oktavia , Sukati Inda
Published: December 2022

Dengan hadirnya e-commerce kemampuan untuk menjual dan membeli kebutuhan sehari-hari konsumen secara langsung telah disediakan dan dipermudah oleh Internet. Promosi sangat penting bagi bisnis dalam mengkomunikasikan barang kepada pelanggan, perusahaan akan menggunakan promosi untuk menunjukkan kualitas produk dan mendorong pelanggan untuk membeli. Pembelian impulsif sering terjadi hanya karena untuk memenuhi keinginan seseorang dalam bergaya hidup. Tujuan penelitian ini adalah untuk menganalisis apakah terdapat pengaruh antara variabel promosi, life style, dan kualitas produk terhadap impulse buying shopee di Kota Batam. Jenis penelitian yang diterapkan penulis ialah penelitian kuantitatif dengan menggunakan sifat replikasi. Pengumpulan data dilakukan melalui penyebaran kuesioner dengan bantuan google form. Jumlah populasi yaitu 400 responden yang pernah melakukan pembelian di aplikasi shopee. Pendekatan yang digunakan dalam penelitian ini ialah Nonprobability Sampling dengan Purposive Sampling. Pengujian data menggunakan alat olah data SPSS 25. Temuan pada penelitian ini secara parsial promosi tidak memiliki pengaruh yang positif dan signifikan terhadap Impulse Buying dimana nilai t hitung -0,522 < t tabel 1,966 dan nilai sig 0,602 > 0,05, dan life style memiliki pengaruh yang positif dan signifikan terhadap Impulse Buying dimana nilai t hitung 12,887 > t tabel 1,966 dan nilai signifikansi 0,000 < 0,05 serta kualitas produk memiliki pengaruh yang positif dan signifikan terhadap Impulse Buying dimana nilai t hitung 5,992 > t tabel 1,966 dan nilai signifikansi 0,000 < 0,05. Dan secara simultan promosi, life style, dan kualitas produk berpengaruh positif dan signifikan terhadap impulse buying shopee di Kota Batam dimana nilai f hitung 199,129 > nilai f tabel 2,63 dan nilai sig sebesar 0,000 < 0,05.
How the noises could affect marine food webs? A lack of zooplankton’s studies.
Authors: Prosnier Loïc
Published: December 2022

There is a growing interest in the effects of noise pollution on marine ecosystems. To date, these works mainly focus on hearing species, especially fish and mammals. Because these species are generally at the upper trophic levels, key species from lower levels, like zooplankton species, are less studied under noise effects. Zooplankton is already used as bioindicators, to understand fluxes, ecological dynamics and global change effects; however, it remains a lack of knowledge on the effect of noise. Previous works demonstrate that they could detect vibrations. Consequently, noise is susceptible to affect the perception of their environment and to induce stress. Combining their short life cycle, their phylogenetic and ecological diversity, zooplankton could be useful organisms to understand a diversity of noise effects. They can be used to study the effects at individual scales as modifications of physiology, development, and behavior. Responses, that could change species interactions and population dynamics, are expected to lead to larger scale implications (i.e., alterations of food webs dynamics and ecosystem functioning). Here, we bring out, from studies in ecology, ecotoxicology, and parasitology, methods that can be adapted to our current questions. We might expect further development of acoustic studies on zooplankton, in order to better apprehend how anthropogenic noises affect marine environments.
Managing industrial ecosystems in a united digital space
Authors:   Moscow Aviation Institute, Kovalchuk Julia A. ,   Financial University under the Government of the Russian Federation, Stepnov Igor M. ,   Financial University under the Government of the Russian Federation
Published: December 2022

Subject/topic. The article presents an original assessment of the development of interaction management systems in modern ecosystems in the context of industrial development and the formation of a united digital space. Goal. The research aims to substantiate approaches to the development of conceptual solutions for the effective management of industrial ecosystems. Methodology. A critical analysis of the spread of the ecosystem approach for integration in industry in the presence of general management patterns is carried out. Results. The factors of formation of a new management model in a united digital space are determined: historical heritage, decentralization/centralization, duality of the management model, feedback, services, cyclicity, technologies, management virtualization, digital trust and digital responsibility, architecture of management structures. The dual nature of new processes is substantiated, when a single system forms two spheres of management (the development management system itself and the interaction management system), interconnected by feedback. It is shown that for an effective production ecosystem, the level of formation of value chains remains the prerogative of participants, which fundamentally distinguishes the ecosystem approach from the cluster approach. The potential of the ecosystem model as an infrastructure or service model, as opposed to a cluster product model, has been established. The technological aspect of management is highlighted, which is based on the property of modern technologies to separate the control and transformational parts, presenting the possibilities of technology management in a digital environment, which creates more effective integration into a united digital space and the inclusion of augmented reality technologies in interaction with cyber-physical systems that ensure the information reliability of managed objects. Conclusions. The differences of the management system in the classical, cluster and ecosystem models are established and a conceptual vision of the possibilities of updating it is formed, taking into account the identified ideas about the structure of interaction in the ecosystem and management efficiency criteria (metrics).
Russian macroeconomic production function in regard to infrastructure for 1990-2020
Authors:   Central Economics and Mathematics Institute Russian Academy of Science, Afanasiev Anton А. , Ponomareva Olga S. ,   Central Economics and Mathematics Institute Russian Academy of Sciences
Published: December 2022

In the period 1990-2020, the econometric methods were used to study the national economic production function of Russia, one of the arguments of which is the transport and communication infrastructure represented by the main funds of transport and communications. The results of the study indicate a continuing decline in the elasticity of Russia's GDP in transport and communication infrastructure in 2020 at a lower rate than in previous years. The dynamics of the marginal rate of technological substitution of production factors in 2009-2020 is researched. Among the main reasons for the decline in the elasticity of GDP for transport and communication infrastructure, the economic downturn and a decrease in the volume of capital investments in transport and communication industries were highlighted. It is noted that the spread of the Wuhan coronavirus in Russia has somewhat slowed down the rate of decline in the elasticity of GDP in infrastructure due to the sharply increased role of its communication component. For the successful implementation of the policy of advanced infrastructure development announced by the President of Russia, it is necessary not only to increase the volume of investments in infrastructure bottlenecks, but also to adopt an additional set of measures aimed at stimulating economic growth, among which, in the conditions of sharply increased foreign economic and foreign policy restrictions for Russia from our Western and overseas neighbors in 2022. it is possible to highlight the weakening of the centuries-old dependence of the Russian economy on raw materials and, as academician S.Yu. Glazyev, the transition of our country's economy to a new technological order.
Ciliated Peritrichous Protozoa in a Tezontle-Packed Sequencing Batch Reactor as Potential Indicators of Water Quality
Authors: Rivas-Castillo Andrea M. , Garcia-Barrera Antonio A. , Garrido-Hernandez Aristeo , Martinez-Valdez Francisco J. , Cruz-Romero Maria S. , Quezada-Cruz Maribel
Published: December 2022

The presence of colonial and solitary ciliated peritrichous protozoa was determined in a Sequencing Batch Reactor system filled with tezontle, a volcanic rock, economic, and abundant material that can be found in some parts of the world, like Mexico. The presence of these protozoa was related to the removal efficiencies of organic matter. Also, two novel staining techniques are proposed for staining both colonial and solitary peritrichous protozoa. The results show that tezontle promotes the growth of solitary and colonial ciliated peritrichous protozoa, which, once identified, could be used as indicators of the efficiency of the wastewater treatment process. Additionally, the staining techniques established in the current study allowed the precise observation of protozoan nuclei. They can represent a useful complementary methodology for identifying protozoan species present in water treatment processes, along with the already existing identification techniques. The number and variety of protozoa found in the system may be considered potential bioindicators of water quality during biological treatments.
ІСТОРИЧНИЙ ШЛЯХ ВІЙСЬКОВОГО ІНСТИТУТУ КИЇВСЬКОГО НАЦІОНАЛЬНОГО УНІВЕРСИТЕТУ ІМЕНІ ТАРАСА ШЕВЧЕНКА (1991–2021 рр.)
Authors: Вановська Інна , Скрябін Олександр
Published: December 2022

В статті проаналізовано історичний шлях Військового інституту Київського національного університету імені Тараса Шевченка (далі – ВІКНУ) за 30 років незалежності України (1991–2021 рр.).

Автори розподілили цей шлях на два періоди, умовно виділивши в них чотири етапи. З 1991 по 1997 рік Відділення військової підготовки, як структурний підрозділ університету, що займався військовою підготовкою студентів, поступово перейшов до виконання більш серйозних завдань, пов’язаних з підготовкою кадрових офіцерів за низкою важливих для армії спеціальностей. Створений у 1998 році на базі Відділення військової підготовки Військовий інститут поступово став сучасним військовим навчальним закладом, що здійснює підготовку офіцерів з повною вищою освітою для Збройних Сил України та інших структур сектору безпеки і оборони України. Основними спеціальностями, що отримують тут офіцери є “Філологія”, “Політологія”, “Психологія”, “Журналістика”, “Фінанси, банківська справа та страхування”, “Право”, “Геодезія та землеустрій” і “Міжнародні відносини, суспільні комунікації та регіональні студії”.
„Lehettem volna” – A pedagógusok eltérítő hatása a pályaválasztásban
Authors: Pálvölgyi Áron
Published: December 2022

A cikkben azt vizsgálom, hogy a pedagógusoknak van-e eltérítő hatása a pályaválasztásban. Saját kutatás eredményeként olyan példákat mutatok be, amelyeknél a pedagógusoknak beazonosítható szerepe volt abban, hogy a diákok változtattak a pályaválasztásuk irányán, vagyis már volt elképzelésük, de tanári hatásra tértek el attól. A cikk célja gyakorlati példákon keresztül igazolni, hogy egy-egy pedagógus jelentősen tudja befolyásolja a pályaválasztást, és el is tud téríteni a tanulók eredeti szándékától. Tehát az interjúalanyaimnak – saját bevallásuk és megítélésük szerint – volt olyan tanáruk, akinek eltérítő hatást tulajdonítanak a pályaválasztás során. Célom a tudatosítás. Mivel egyes esetekben a pedagógusok nem is tudják, hogy a viselkedésük vagy egy-egy mondatuk valamelyik diákjuk életében meghatározó volt, ezért a példák bemutatásával ez a tu-datosság növelhető.
A térségfejlesztés humántényezői
Authors: Sós Tamás
Published: December 2022

Recenzió Malatyinszki Szilárd: Térségfejlesztés és emberi erőforrás című, a Gondolat Kiadó gondozásában 2021-ben megjelent könyvéről
Beszámoló a Magyar Pedagógiai Társaság Szakképzési Kollégiuma ”Beszélgetések a szakképzésről” című programsorozatának rendezvényéről
Authors: Schindler Rózsa
Published: December 2022

Beszámoló a Magyar Pedagógiai Társaság Szakképzési Kollégiuma által szervezett ”Beszélgetések a szakképzésről” című programsorozat 2022. október 6-án megtartott személyes jelenléttel és online térben is zajló (hibrid) rendezvényéről.
Double father trouble: a daughter's struggle with paternity
Authors: Settle Victoria
Published: December 2022

In this article I will consider the complexity of the relationship between a daughter and her father within the context of the wider family constellation, and how working with a male analyst evoked both transferential and countertransferential material. When we are attachment figures to our clients, we can be particularly evocative of the same-sex parent because of the ways in which the transference is embodied in the flesh. In this case, the male analyst became over identified with my client's father in ways that were problematic for her and for the work.
Postoperative Perfusion Magnetic Resonance Imaging as a Tool for Predicting Survival in Glioblastoma of the Brain
Authors:   S.P. Botkin City Clinical Hospital, Outpatient Cancer Care Center, Moscow, Russia, Rozanov I.D. , Bunak M.S. ,   M.F. VladimirskyMoscow Regional Research Clinical Institute, Moscow, Russia, Glazkov A.A. ,   M.F. VladimirskyMoscow Regional Research Clinical Institute, Moscow, Russia, Stepanova E.A. ,   M.F. VladimirskyMoscow Regional Research Clinical Institute, Moscow, Russia, Lebedev S.S. ,   S.P. Botkin City Clinical Hospital, Outpatient Cancer Care Center, Moscow, Russia, Balkanov A.S. ,   M.F. VladimirskyMoscow Regional Research Clinical Institute, Moscow, Russia
Published: December 2022

Glioblastoma is the most frequently detected primary brain tumor (pGB), the prognosis of which significantly depends on the magnitude of residual GB (rGB), for which magnetic resonance imaging (MRI) is used in the postoperative period. Purpose: To analyze the data of ASL perfusion MRI (ASL-pMRI) performed prior to adjuvant radiation therapy (aRT), 6 to 8 weeks after resection of pGB, in terms of their prognostic significance for survival in this group of patients. Material and methods: The study included 54 patients (median age ‒ 58 years; gender: 29 men, 25 women). The Karnovsky index in 81.5 % of patients was ≥80 %. To visualize and calculate the dimensions of the rGB, ASL-pMRI was used according to the type of pseudo-continuous three-dimensional marking of arterial spins. The focus/foci of hyperperfusion (CBFmean > 64 ml/100g/min) in the area of the wall of the postoperative cyst were considered as rGB. Results: Survival in the total group of 54 patients with pGB was 18 months (95 % CI:14.23) . The use of ASL-pMRI made it possible to visualize rGB in 37 (68.5 %) patients. The probability of visualization of rGB was significantly higher (p=0.02) in the case of temporal localization of the tumor. Age (HR:1.04; 95 % CI: 1.01‒1.07; p=0.007), the maximum diameter of the rGB (HR:1.04; 95 % CI: (1.01‒1.07); p=0.03) and localization of pGB in the temporal lobe (HR:2.00; 95 % CI: 1.05‒3.80; p=0.034) had a significant negative impact on survival. The use of the multifactorial Cox model showed that only the age ≥60 years (HR:2.78; 95 % CI:1.26‒6.15; p=0.012) and the maximum diameter of rGB ≥25 mm (HR:3.35; 95 % CI:1.36‒8.22; p=0.008) retained their significant negative impact on the survival of patients with pGB. Conclusions: the use of ASL – pMRI 6 to 8 weeks after resection of pGB indicates that the results obtained can become an effective tool for predicting survival in this group of patients.
Digital Twin as a Product of the Information Society. New Opportunities for Research in the Field of Medical Radiology
Authors:   A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia, Baranov L.I.
Published: December 2022

Introduction. The development of mass communications and Internet access in Russia and the World as a prerequisite for digitalization. Information society. Knowledge society. Digital environment. Information space. The concept of digital twins. Unified system of identification and authentication (ESIA). Digital profile. Some prospects for improving the organization of medical research, including in the field of medical radiology, in the context of the development of medical information space.
INDONESIAN AFFIXATION ATTACHED TO ENGLISH WORDS IN ADOLESCENT TABLOID
Authors: Rasika Dede Jihan
Published: December 2022

This paper analyzes the pattern of Indonesian affixation which is attached to English words found in 4 famous Adolescent Tabloid namely Keren Beken, Gaul, Fantasi, and Genie. The data were collected by reading the tabloids and taking notes of English words that are being attached by Indonesian affixes. The patterns of those words were analyzed whether or not the affixation changed the word class of English words. From the analyses, it is revealed that Indonesian affixation can be attached to English words. After being attached to English words, Indonesian affixes changed the word class of English words.
STUDENTS’ ENTHUSIASM IN LEARNING IN THE COVID-19 OUTBREAK
Authors: Akbarjono Ali , Belawati Elvani , Afriani Zelvia Liska
Published: December 2022

The purpose of this study is to determine student excitement for studying English during the Covid-19 outbreak, as well as the ways in which teachers encourage student enthusiasm for learning English throughout the outbreak. A qualitative research design was adopted in this study. The subjects of this study are students of class XI in MAN 1 Model Bengkulu class XI A, totaling 30 students. The study's findings revealed that pupils in class XI MAN 1 Model Bengkulu are enthusiastic about learning English. Based on observations and interviews with students from MAN 1 Model Bengkulu class XI. As indicated by the reduction in the English value of class XI MAN 1 Model Bengkulu pupils during the Covid-19 outbreak, the findings show that most students have a low level of excitement when studying. The observation checklist and interview used to observe the activities of students and teachers in the English class. To analyzing the data, the researcher was apply (1) data reduction; (2) data display; and (3) drawing and verifying conclusionTeachers use various strategies so that the enthusiasm of students in learning English during the Covid-19 outbreak continues to increase, namely by using interesting learning videos and giving quizzes to students. Keywords: Student Enthusiasm, Learning English, Covid-19 Outbreak.
Medical student’s perception of their academic performance in emergency remote teaching during the Covid-19 pandemic
Authors: Araújo Neto Aécio Flávio Bezerra de , Carvalho Neto Antonio de Pádua Medeiros de , Omena Adriana de Carvalho Silva de , Duarte Elves dos Santos , Souza Evandro Everson Silva , Santos Jaqueline Maria Silva dos , Ferreira Júnior Genildo Cavalcante , Matos Rocha Thiago José
Published: December 2022

Due to the pandemic related to the new coronavirus (SARS-CoV-2). which causes the disease entitled "Covid-19". And the effects of the quarantine and social distancing taken by the population the face-to-face classes of about 1.5 billion students in 165 countries were suspended. This study therefore is aimed to evaluate the perception of medical students about academic performance in emergency remote teaching during the Covid-19 pandemic. A descriptive quantitative cross-sectional study was carried out with 226 medical students from 4 medical institutions in Alagoas. The research uses as a data collection instrument a virtual questionnaire on Google Forms®️ of an anonymous and voluntary nature being disseminated through applications and social networks and intended for all medical students in Alagoas. The results obtained highlight students' interest in maintaining their studies remotely. However the lack of means to access and use such technologies as well as socio-economic situations and the lack of motivation and influence of the home environment proved to be determinant factors for the continuity and effectiveness of the studies.
Diatomite filler for resin composites application – A new approach for materials improvement
Authors: Araújo Isaac Jordão de Souza , Zanini Maurício Matté , Guarda Maurício Bottene , Fronza Bruna Marin , Consani Simonides , Lima Isabela Pinheiro Cavalcanti , Correr Américo Bortolazzo
Published: December 2022

The aim of this study was to evaluate physical-mechanical properties, degree of conversion, and chemical stability of a nanohybrid composite containing diatomite as filler. Degree of conversion (DC%) of diatomite-containing composite (Zirconfill®) was performed using FTIR immediately, and 1-, and 7-days post-curing. SEM was conducted to evaluate the surface of the resin after curing and measure particles size. Also, elemental characterization was performed to verify the major components of the composite through EDS. Mechanical characterization using 3-point bending test was performed prior and after thermo-cycling (10000 cycles) (n=10). Knoop microhardness (KHN) was used to characterize mechanical stability after chemical solutions aggression (water, juice, coffee, coke) up to 28 days (n=10/solution). After data normality evaluation using Shapiro-Wilk, One-way ANOVA and Tukey post hoc were conducted to verify differences between groups for DC% and mechanical properties. Split-plot ANOVA was used to compare groups for microhardness characterization (α=0.05). Immediate DC was 60% and significantly increased up to 80% at 7 days (p<0.05). Flexural strength of the diatomite-containing composite was 136.2 (23.7) MPa and significantly decreased to 75.1 (10.2) as a result of thermo-cycling. The flexural modulus was not significantly affected by the thermo-cycling (p>0.05). All the dietary solutions affected the KHN of the composite up to 21 days. For 28 days, the KHN evidenced and stabilization regarding all the solutions. Diatomite-containing composites present good degree of conversion and relevant mechanical properties and demonstrate time-dependent stability against chemical degradation.
Uso de antidepressivos na infância e adolescência
Authors: Matos Wysley Alves , Soares Rafael Nascimento , Santos Marcos Vinícios Ferreira dos
Published: December 2022

Esse trabalho traz reflexões acerca de uma assunto delicado, pois quando o objeto de estudo é criança e adolescente, é necessário, que seja estabelecido um histórico médico detalhado para a introdução medicamentosa em curto prazo, pois as crianças e adolescentes tendem a reagir mais rápido à medicação que os pacientes adultos. O estudo tem como objetivo apresentar as principais prescrições  de medicamentos para o tratamento e suas indicações. O texto é um recorte de uma revisão integrativa da literatura realizada sobre  depressão em crianças e adolescentes. Os autores pesquisados afirmam que os medicamentos são capazes de combater a depressão, porém o uso de antidepressivo em crianças e adolescentes tem crescido nos últimos anos, fatores estes que podem ser apontados por pressões externas, contribuindo para que a ansiedade fisiológica progrida cada vez mais para a patológica. No entanto, o uso indiscriminado de medicamentos é capaz de comprometer a saúde emocional e física do paciente e seu bem-estar em geral, principalmente, do paciente infantil, que apresenta resistência imunológica ainda em construção. A prescrição de antidepressivos deve ser cautelosa e pontual, pois exige do profissional que a prescreve conhecimentos sobre os protocolos adequados para a administração medicamentosa, no que diz respeito à dosagem correta do medicamento, a composição química e as reações adversas do mesmo; além da necessidade de saber detalhes sobre o histórico médico do paciente infantil e/ou adolescente. Dessa forma, considera-se que a prescrição dos medicamentos precisam acontecer de modo controlado.