bluuebunny/crossref_metadata_2025 huggingface dataset:
Referências locais de qualidade educacional: Estudo comparado das trajetórias de Sobral/CE e Oeiras/PI
Authors: Da Fonseca Neto João César , Sol Geraldina Vicente , De Oliveira Brito Renato
Published: July 2021

Este artigo é resultado de uma pesquisa de Educação Comparada sobre as trajetórias das reformas educacionais realizadas nas duas últimas décadas pelos municípios de Sobral/CE e Oeiras/PI. A partir dos resultados do último PISA, o texto discute os diferentes conceitos de “qualidade” em educação, para em seguida contextualizar as unidades de análise e apresentar os resultados dos seus principais indicadores educacionais. A comparação das duas trajetórias destaca semelhanças e especificidades de cada processo, indicando estratégias de atuação que podem ser replicadas em outros lugares, mas também reconhecendo a importância do desenvolvimento de soluções locais adequadas a cada realidade. Ao final, constata-se que em tempos e condições distintas, Sobral e Oeiras têm conseguido avançar significativamente na efetivação do direito à aprendizagem, e que comparações intranacionais constituem fonte promissora para novas investigações e políticas de reforma educacional voltadas para a qualidade.
Anti-vibrio effects of the precious Tibetan pill, Rinchen Drangjor Rilnag Chenmo (RDRC)
Authors: Dhargyal Sonam , Philip Indhu , Biswas Soma , Sarojini Suma
Published: July 2021

Tibetan precious pills are an integral part of TTM (Traditional Tibetan Medicine). Among them, Rinchen Drangjor Rilnag Chenmo (RDRC) has been named “King of Precious Pills” due to its efficacy in treating a multitude of human disorders. RDRC has a complex formulation with about 140 ingredients, mostly from medicinal plants and a few precious stones and metals. Not many studies have been done on the experimental validation of antimicrobial properties of this important pill. The current study investigated the antimicrobial activity of the extracts of RDRC. Both aqueous and chloroform extracts were evaluated for their antibacterial potential against a total of seven different bacterial species, which are pathogenic, including three species of Vibrio, viz. V. vulnificus, V. parahaemolyticus and V. harveyi using the well-diffusion method and also by assessing MIC and MBC values. Its antifungal potential was also studied against two fungal strains Aspergillus niger and Talaromyces islandicus. It was found that the chloroform extract of RDRC exerted a positive antibacterial effect on all the Vibrio species tested, and the least MIC of 3.33 mg/ml was observed for V. parahaemolyticus. This is the first study of its kind on the anti-Vibrio effect of the Tibetan precious pill, Rinchen Drangjor Rilnag Chenmo.
The User Experience Test of Augmented Reality based AAC Application
Authors: Park Hye Seon , Yeon Seok Jeong ,   Korean Society of Augmentative and Alternative Communication
Published: July 2021

Background and Objective: The purpose of this study was to examine the user experience and availability in the field of education, and to examine support plans for effective use of this application. Method: By developing a scenario task to evaluate the major functions and the reliability of Augmented Reality (AR) based AAC application. The availability of AR-AAC application was evaluated on a 5-point scale for nine special teachers who completed AAC-related training for more than 10 hours. We evaluated and conducted interviews related to support plans for effective use of the application. Results: Most of the items in the reliability evaluation of the AR-AAC application received positive feedback. The lightness of the symbols and letters, the consistency of the color combination of the symbol, and the clarity of the voice received the highest evaluation. However, the speed of reaction when selecting a symbol and the design evaluation to prevent errors were both rated poorly. Conclusion: The AR-AAC application was found to be positive as it has improved vocabulary learning, discriminated picture symbols, and shortened preparation time through matching between actual communication situation scenes and picture symbols. However, it was found that the user had difficulties in manipulating it and the vocabulary was limited, so further improvement was required.
Basic Human Values and Attitudes Towards a Universal Basic Income in Europe
Authors: Choi Gwangeun
Published: July 2021

This study contributes to the emerging literature on public opinion on a universal basic income (UBI) not only by investigating the role of basic human values in influencing support for UBI but also by examining the moderating role of welfare state development in the association between basic human values and UBI support. Using the European Social Survey (ESS) Round 8 in 2016, which has an item asking whether to support UBI and the 21-item measure of human values that is based on the Schwartz theory of basic human values, the results show that individual universalism that is a self-transcendence value is positively and significantly associated with support for UBI, while the other self-transcendence value, benevolence, has a negative relationship with that; the two self-enhancement values, power and achievement, are positively linked to support for UBI. Additionally, in advanced welfare states, people who are more inclined towards individual universalism are more likely to support UBI; by contrast, in underdeveloped welfare states, this relationship is not apparent.
A morphological classification of the fat particles found in the urinary sediment of patients with Fabry disease
Authors: Fogazzi Giovanni B. , Garigali Giuseppe , Pieruzzi Federico , Corbelli Alessandro , Fiordaliso Fabio , Consonni Dario , Messa Piergiorgio
Published: July 2021

Objectives

The search in the urinary sediment (U-sed) of fat particles with peculiar morphology is a simple and inexpensive tool for the diagnosis of Fabry disease (FD) nephropathy. In this study we investigated the morphology of a high number of such fat particles with the aim to obtain a morphological classification to be used for their identification.

Methods

Study of the morphology of fat particles in the U-sed of a cohort of FD patients using: bright field plus phase contrast microscopy (BF + PC), polarized light microscopy (POL), and transmission electron microscopy (TEM). Comparison of these results with those obtained for the fat particles seen in the U-sed of a control group (CG) of patients with non-FD glomerulopathies.

Results

FD: 18 U-sed from six patients (three samples/patient) were prospectively investigated and 506 fat particles identified. With BF + PC, these were classified in eight morphological categories (seven of which were confirmed by TEM), and with POL in 10 others. CG: eight U-sed from eight patients were investigated and 281 fat particles identified. These fell into four BF + PC morphological categories and into eight POL categories. While some categories were significantly more frequent in FD others were more frequent in the CG.

Conclusions

Our study demonstrates that 1. The morphology of fat particles found in the U-sed of FD patients is much wider and complex than that described so far 2. Several significant differences exist in the morphology of such fat particles between FD and CG patients.
Diagnostic algorithms for non-ST-segment elevation myocardial infarction: open issues
Authors: Clerico Aldo , Aimo Alberto , Zaninotto Martina , Plebani Mario
Published: July 2021

The use of serial measurement of cardiac troponin (cTn) is recommended by international guidelines for the diagnosis of myocardial infarction (MI) since 2000. This article focuses on factors influencing temporal changes in high-sensitive cTn (hs)-cTn and the impact of these factors on the diagnosis of non-ST-segment elevation MI (NSTEMI). The recommendations proposed by three different international guidelines published in 2020–2021 for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation (NSTE) show some discrepancies. In particular, there is no agreement among these guidelines about cut-off or absolute change values to be used for the rule-in, especially regarding the use of sex-specific cut-off values. Furthermore, there are no sufficient evidences on the diagnostic accuracy and cost effectiveness related to cut-off values suggested for algorithms to be used by some hs-cTnI methods.
Broaden the Pathway to Inclusive Entrepreneurship: A Transaction Cost Proposition
Authors: Du Jian , Lu Jie , Jiang Yanbing
Published: July 2021

Since entrepreneurship was conceptualised as a panacea for achieving inclusive growth in the “base of the pyramid” (BoP) regions, various ways have been explored to leverage this powerful tool, such as helping potential entrepreneurs build the resource base and capabilities. However, given the severe resources constraints in the BoP regions, such a goal is difficult to achieve. Besides, due to the high demands on personal competence, only a few people can benefit from this method, which fails to solve the problem of social exclusion in the BoP regions. Therefore, we aim to find a better way to leverage entrepreneurship to tackle the problem of the BoP regions by calling for more attention to the inclusiveness of entrepreneurship. Based on data of inclusive entrepreneurs in Zhejiang, China, we construct a three-stage model for inclusive entrepreneurship. We also apply Transaction Cost Economics to look for determinants that foster inclusive entrepreneurship and validate our main assertion that decreasing transaction cost significantly helps to increase the inclusiveness of entrepreneurship, and different phases of inclusive entrepreneurship (i.e., opportunity inclusiveness, participation inclusiveness, and sharing inclusiveness) are influenced by different sets of determinants of transaction costs.
Grausamkeiten in Grimms

Kinder- und Hausmärchen
Authors: Soo Kim Yeon
Published: July 2021

Der Beitrag untersucht den kulturellen und kolonialistischen Kontext, aus denen heraus Grimms Märchen in den 1920er Jahren in Korea übersetzt wurden. Es wird gezeigt, wie und inwiefern diese Übersetzungen der Strategie folgten, die japanische Kolonialherrschaft anzuklagen und sich zugleich der kulturellen Eigenständigkeit Koreas zu versichern. Der Fokus richtet sich auf grausame Szenen in Grimms Märchen, die einerseits wortgetreu, andererseits abmildernd übersetzt wurden. Dabei spielte die erste Richtung auf Grausamkeiten der Kolonialmacht an und pointierte die Bestrafung des Bösen, die zweite setzte mehr auf die Erziehung von Kindern und Jugendlichen als den Hoffnungsträgern für die Zukunft der Nation. Damit folgten koreanische Übersetzer wie Choi Nam Seon und Bang Jeong Hwan nicht zuletzt Intentionen, wie sie die Brüder Grimm unter napoleonischer Herrschaft in Deutschland vertreten hatten.
First trimester screening with biochemical markers and ultrasound in relation to non-invasive prenatal testing (NIPT)
Authors: Scharf Alexander
Published: July 2021

Non-invasive prenatal testing (NIPT) is often erroneously received as a diagnostic procedure due to its high discriminatory power in the field of fetal trisomy 21 diagnosis (wording: “NIPT replaces amniocentesis”). Already a look at the methodology of NIPT (statistical gene dose comparison of a primarily maternofetal DNA mixture information at selected sites of the genome) easily reveals that NIPT cannot match the gold standard offered by cytogenetic and molecular genetic analysis procedures from the matrix of the entire human genome (origin: vital fetal cells), neither in diagnostic breadth nor in diagnostic depth. In fact, NIPT in fetal medicine in its current stage of development is a selective genetic search procedure, which can be applied in primary (without indication) or secondary (indication-related) screening. Thus, NIPT competes with established search procedures for this field. Here, the combined nuchal translucency (NT) test according to Nicolaides has become the worldwide standard since 2000. The strength of this procedure is its broad predictive power: NT addresses not only the area of genetics, but also the statistically 10 times more frequent structural fetal defects. Thus, NIPT and NT have large overlaps with each other in the field of classical cytogenetics, with slightly different weighting in the fine consideration. However, NIPT without a systematic accompanying ultrasound examination would mean a step back to the prenatal care level of the 1980s. In this respect, additional fine ultrasound should always be required in the professional application of NIPT. NIPT can thus complement NT in wide areas, but not completely replace it.
Isolation and characterization of chemical constituents from Chaerophyllum bulbosum roots and their enzyme inhibitory and antioxidant effects
Authors: Tel-Çayan Gülsen , Deveci Ebru , Molo Zeynep , Duru Mehmet Emin , Öztürk Mehmet
Published: July 2021

Isolation and bioactive effects of the roots of Chaerophyllum bulbosum L. were firstly investigated herein. Enzyme (acetylcholinesterase, butyrylcholinesterase, urease, α-amylase, α-glucosidase, and tyrosinase) inhibitory effects of C. bulbosum root extracts were tested. Three known compounds, n-heptadecanyl eicosanoate (1), stigmasterol (2), and β-sitosterol-3-O-β-d-glucopyranoside (3) were isolated from C. bulbosum. Antioxidant and enzyme inhibitory effects of isolated compounds were investigated. The hexane extract (IC50: 349.58 ± 0.06 μg/mL) displayed a higher α-glucosidase inhibitory effect than the standard (IC50: 378.66 ± 0.14 μg/mL). The best inhibitory effect was found in compound 2 on AChE (46.40 ± 0.31%), BChE (56.41 ± 0.54%), and urease (92.47 ± 0.11%); compound 1 on α-amylase (22.27 ± 0.61%); and compound 3 on α-glucosidase (12.43 ± 0.25%) and tyrosinase (19.00 ± 0.16%). All isolated compounds showed moderate antioxidant effects in all assays. This study contributes to the therapeutic uses of Chaerophyllum roots and emphasizes the value of C. bulbosum species for the development of novel therapeutic agents.
The impact of the local conservative climate on generalised trust in Sweden
Authors:   University of Pécs, Faculty of Sciences, Doctoral School of Earth Sciences, Sümeghy Dávid
Published: July 2021

The rise of the radical right parties, with their anti-immigrant rhetoric, may amplify the generally observed negative impact of diversity on generalised trust. The impact of the conservative climate created by these parties is apparent at the national level, but the little research carried out in the field has yet to examine the role of their local political power. In Sweden, the literature suggests that the radical right Sweden Democrats party has a stronger anti-immigration and ethnonationalist rhetoric at the local level, which may reduce the generalised trust of residents by triggering conflict theory. Calculating the conservative climate based on the percentage of party representatives on local councils using multi-level modelling, we observe that the contextual effect of the conservative climate is present and reduces generalised trust. However, the underlying cause of this effect is not fully known. It can be traced back to the party’s local politics, the residents and the local media.
Special political missions and their role in a preventive diplomacy: opportunities and challenges
Authors:   University of Silesia in Katowice, Faculty of Law and Administration, Institute of Law, International Law and European Law, Poland, Myl Małgorzata
Published: July 2021

Today’s diplomacy is an ambiguous phenomenon which involves many diverse tools and actions undertaken by national and international actors. Diplomacy is undoubtedly one of a key element of international peace and security as it enables disputes and conflicts to be prevented . There is a host of measures and instruments that can be exercised at any stage of a crisis, among which are special political missions. This paper is an attempt to discuss the nature and role of a special political mission in preventive actions. The main attention is paid to the missions established by the United Nations and by the European Union. The considerations resulted in listing strengths of the special political missions and in identifying the challenges that should be faced in order to increase an effectiveness of the missions.
The Role of Institutions in the Technology Transfer Process with Particular Focus on Technology Parks in Poland
Authors:   University of Bialystok, Poland, Protasiewicz Anna , Trzaska Karolina ,   University of Bialystok, Poland
Published: July 2021

This article addresses the issue of technology transfer in the context of institutional conditions of this process with particular focus on intermediary institutions, such as technology parks. The study presents the role of institutions in the effective process of technology transfer. The research conducted by the Polish Agency for Enterprise Development and the Association of Organizers of Innovation and Entrepreneurship Centres in Poland was used.
Corruption in the Balkans as an Obstacle to the Three-Seas-Initiative Overview of Anti-Corruption Institutions in Bulgaria, Croatia, Poland, Romania and Slovenia
Authors:   University of Bialystok, Poland, Zawadzki Paweł
Published: July 2021

The aim of this article is to show the high level of corruption offences and the ineffectiveness of the existing legal and institutional solutions in the Balkan states, which are part of the Three-Seas initiative. The effectiveness of the regulations in force in these countries deviates from the standards set by the European Union. This has implications for the success of the Three-Seas-Initiative. The current state of affairs is the result of clashing ideas about the membership of Balkan countries in a particular sphere of influence. The services of the Russian Federation (GRU or SWR) play a significant role in maintaining the current status quo. Observation of corruption offences in the Balkans shows that the bodies set up to investigate corruption offences do not have effective powers to prevent, detect and prosecute such offences. An evaluation of the regulations in force in this area shows that they are ineffective. A solution which would ensure that the Balkans meet European standards on preventing and combating corruption could be theimplementation of the institutional model of the Central Anti-Corruption Bureau in force in the Republic of Poland by reforming the Balkan anti-corruption services.
Joint Physical Custody After Parental Separation: A Polish Perspective
Authors:   University of Silesia in Katowice, Poland, Kamińska Katarzyna
Published: July 2021

The aim of this paper was to present the characteristics of joint physical custody in Polish family law. For this purpose the relevant regulations of the Polish law were analysed. In the paper, the substantive as well as the procedural provisions were compared. The Family Court may award joint physical custody if the parties have made an agreement, consistent with the welfare of the child, or in the absence of such a parenting agreement, having regard to a child’s right to both parents. One hypothesis assumes that joint physical custody does not mean only symmetric child custody arrangements, and its proper application by courts is determined by taking into account many different factors. In the paper, the results of the examination referred to joint custody in child custody law in Germany and the Swedish experience of joint physical custody, were presented. The main advantage of joint physical custody is to provide both parents equal control over decision regarding a child’s upbringing and to split the time that a child spends living with each of them. This paper contains a reflection on joint physical custody in the face of COVID-19. The current pandemic is having an enormous impact on families. During this particular time, it is time to become more cooperative and more fluid, not less.
Żyć mocą Ducha Bożego w Kościele
Authors:   Wyższe Seminarium Duchowne w Elblągu, Neumann Jacek
Published: July 2021

Our life as the Christen in the community ecclesial is the announcement about God, which gives the people the gifts of love, freedom, friendship and truth. Through the forgiveness and the activity of the salvation of God, love and friendship in man’s life makes the human world more divine. This Jesus accents in His proclamation about the kingdom divine, specially in the parables, where He presents the model of the world based on love, hope, faith and freedom as the world of deeds based on God. Therefore, with the power of God’s Spirit, man has to make his life based on the norm of divine, because only in God, with God and through God exists for man the possibility to life now on earth, and afterwards in the future in heaven. In this situation, the answer of the man of faith has to be the motivation to take up the “deed” of the renovation of self-life and the imitation of God. This constitutes as the Christian thought that the central point of the theological interpretation of the value of salvation is realized – hic et nun – as the historical and existential value of the human life in the right of the kingdom divine. The proclamation of Jesus about the “new life”, presents to man the values of the divine existence in the spiritual of the Church. On one hand, it is the gift of freedom and the liberation from sin, where the love of God is absolutely necessary. On the other hand, the “new life” opens for man the space of liberty of life, where God forgives the human offences and the sins, both past and present. Well now the resume of the call to imitate God is the acceptance of the divine gift, which changes the man himself, and all the people, who seek the help and good councils to live the norm divine. These witnesses in the human mentality the consciousness of the existence based on the divine laws, which have in themselves the dimension eschatological.
Eklezjalne i naukowe zadanie teologa w świetle instrukcji Donum Veritatis Kongregacji Nauki Wiary
Authors:   Uniwersytet Papieski Jana Pawła II w Krakowie, Królikowski Janusz
Published: July 2021

In this article the instruction Donum veritatis on the vocation of the theologian in the Church, published by the Congregation for the Doctrine of Faith on 24th May 1990, is treated as the benchmark for the undertaken reflection on the ecclesial and scientific dimension of theology. This document still constitutes an abundant source of guidelines concerning theology and the way in which it should be pursued by each and every Catholic theologian. The instruction draws the attention primarily to a personal vocation of the theologian who remains in the service of the fellowship of God’s People. It results from the very nature of the truth revealed by God which was mercifully conveyed to man so as to bring him to salvation. The gift of truth defines the nature of theology which is a scientific service to God’s truth and by the same token also to God’s People. One of the key elements of this service is the cooperation with the Magisterium of the Catholic Church while preserving its own autonomy. The principle of complementarity is a key factor in this respect and it also determines the ecclesial character of fulfi lling the vocation of the theologian.
Modele myślenia teologicznego
Authors:   Uniwersytet Papieski Jana Pawła II w Krakowie, Krupka Aneta
Published: July 2021

The article attempts to present the advantages of using models in theology in the context of contemporary methodological challenges. The use of renewed hermeneutics can help to reorganize theological thinking to avoid both treating the content of faith in a matter-of-fact manner and reducing it to personal experience. At the same time, fruits of this thinking can be presented in the form of theological models that are simplified representations of a more complex structure. They must not be overly reductive but as holistic, multifaceted, dynamic, and practical as possible. One of the important proposals is the nuptial model developed by Cardinal Angelo Scola. Using this model seems to be inspiring when applied to support, among other things, the correct understanding of sacramentology.
The Development of ARCS-Based Economic E-Book Media for Senior High School
Authors: Saputri Kartika Yunita , Santoso Sigit , Hindrayani Aniek
Published: July 2021

This study aimed to determine the appropriateness of ARCS-based economic e-books on international trade material in the class XI IPS of Senior High School in terms of experts' assessments and students' responses to e-book products developed. This study used the Borg & Gall development model which was modified into 10 stages, namely: 1) research and information gathering; 2) planning; 3) early e-book product development; 4) initial trials; 5) revision I; 6) main trials; 7) revision II; 8) operational trials; 9) revision III; 10) dissemination. The research was conducted in class XI of Senior High School in Surakarta. Data collection methods in this study used validation sheets and questionnaire sheets which were analyzed descriptively. The results showed the feasibility of an economic e-book based on ARCS qualified "very feasible" for the media aspect with a percentage of 93,75% and the material aspect with a percentage of 88,09% according to experts, and linguist with a percentage of 100% and received a positive response from students with a percentage of 76,11%.
E-Learning Gamelan Ensemble Playing Techniques
Authors: Mazlan Chamil Arkhasa Nikko , Ramli Nor Azman Mohd , Abdullah Mohd Hassan , Uyub Aiman Ikram
Published: July 2021

2020 is a very challenging year because of the covid-19 pandemic and this completely changed the music education landscape. In the past, learning musical instruments could be done face to face, now it is impossible. If no action is taken, this situation could cause stress among students, especially those who learning gamelan ensemble instruments. Unlike other musical instruments, the ensemble gamelan is expensive and student cant afford to buy it. That is why set of gamelan is only owned by the university and placed in the faculty only. Due to this, students who live far away are unable to practice their gamelan instrument due to movement control order these days. Therefore, this study introduces Gamelan E-Learning Techniques, which is the concept of learning gamelan basic hand techniques using a simulation methods for keromong, gambang, saron and gendang. The uniqueness of this study is due to the emphasis on the basic hand techniques of gamelan. By using google class application as well, lecturers can upload learning videos as well as assessment of student game techniques online can be done. This study uses experimental case study method with qualitative approach. The participants consisted of second semester of 36 students who attended the AME 3082 gamelan course at Universiti Pendidikan Sultan Idris (UPSI).
Imitation On The Jaranan Buto Banyuwangi Musical Presentation Structure
Authors: Wiyono Handi
Published: July 2021

Jaranan Buto is one of the arts that live in Banyuwangi in addition to other arts. As a performing art, in every presentation Jaranan Buto uses accompanying music. At the beginning of its creation, the musical accompaniment of Jaranan Buto consisted of several instruments and pieces. Over time, the musical accompaniment of Jaranan Buto has experienced developments so as to form a structure for presenting the musical accompaniment of Jaranan Buto which is now commonly used. This study discusses the structure of the musical accompaniment of Jaranan Buto and its various imitations. This study used a descriptive qualitative approach by interviewing Setro Asnawi (80 years) as the creator of Jaranan Buto and Mariyono (55 years) as the second generation of Jaranan Buto Sekar Diyu dancers who were still active until this research was written. Analysis of research data starts from domain analysis, observation focused on the accompaniment of Jaranan Buto from the beginning of the stage, trance to exiting the stage, taxonomic analysis, selected observations to the final stage, namely component analysis. From these results it can be concluded that the elements of musical imitation in the accompaniment of Jaranan Buto consist of imitation of musical instruments and imitation of pieces performed from other arts.
MafA, NeuroD1, and HNF1β synergistically activate the Slc2a2 (Glut2) gene in β-cells
Authors: Ono Yuka , Kataoka Kohsuke
Published: July 2021

Glucose transporter type 2 (GLUT2), encoded by the SLC2A2 gene, is an essential component of glucose-stimulated insulin secretion in pancreatic islet β-cells. Like that of the gene encoding insulin, expression of the SLC2A2 gene expression is closely linked to β-cell functionality in rodents, but the mechanism by which β-cell-specific expression of SLC2A2 is controlled remains unclear. In this report, to identify putative enhancer elements of the mouse Slc2a2 gene, we examined evolutional conservation of the nucleotide sequence of its genomic locus, together with ChIP-seq data of histone modifications and various transcription factors published in previous studies. Using luciferase reporter assays, we found that an evolutionarily conserved region (ECR) located approximately 40 kbp downstream of the transcription start site of Slc2a2 functions as an active enhancer in the MIN6 β-cell line. We also found that three β-cell-enriched transcription factors, MafA, NeuroD1, and HNF1β, synergistically activate transcription through this 3’ downstream distal enhancer (ECR3’) and the proximal promoter region of the gene. Our data also indicate that the simultaneous binding of HNF1β to its target sites within the promoter and ECR3’ of Slc2a2 is indispensable for transcriptional activation, and that binding of MafA and NeuroD1 to their respective target sites within the ECR3’ enhances transcription. Co-immunoprecipitation experiments suggested that MafA, NeuroD1, and HNF1β interact with each other. Overall, these results suggest that promoter-enhancer communication through MafA, NeuroD1, and HNF1β is critical for Slc2a2 gene expression. These findings provide clues to help elucidate the mechanism of regulation of Slc2a2 gene expression in β-cells.
La iglesia parroquial de San Pedro Advíncula en Redueña. Elemento del patrimonio cultural del municipio y testigo de su historia
Authors: Arroyo Ana
Published: July 2021

La iglesia parroquial de San Pedro Advíncula, de la que se carece de un estudio completo, es el edificio conservado más antiguo del patrimonio arquitectónico de Redueña (Madrid) y como tal, ha sido testigo de buena parte de los eventos históricos sucedidos en el municipio. El estudio de sus fases constructivas y de algunos de sus elementos más sobresalientes, unido a la investigación de la documentación municipal, han permitido conocer buena parte de su evolución arquitectónica y ponerla en relación con la historia local. La presente contribución ofrece por primera vez un estudio detallado de esta iglesia y, a través de este, de buena parte de la historia de Redueña.
Educación del príncipe, nobleza y caballería en el De regimine principum castellano (segundo y tercer libro)
Authors: Gille Levenson Matthias
Published: July 2021

Este artículo propone un estudio de las dos primeras versiones de la traducción castellana de De regimine principum de Egidio Romano, la conocida como Glosa castellana al “Regimiento de los príncipes”, centrándose en la relación entre educación masculina y algunos conceptos políticos claves como los de nobleza y caballería. Tras proponer un análisis de la expresión recurrente «e mayormente los reyes» y poner de relieve las características principales de la oposición entre educación real/nobiliaria y educación del común, el estudio se centra en la relación entre sabiduría, virtud y nobleza: parecen relacionarse más estrechamente estos conceptos a medida que se va modificando el texto entre el original latino y la segunda versión, adaptándose poco a poco el texto a un nuevo contexto político e ideológico. Finalmente, se estudia la figura del caballero y su relación con las letras para poner de relieve cierta tensión a la hora de definir la caballería.
Las prosas caballerescas castellanas y sus versiones italianas en ottava rima: el Palmerino y el Primaleone de Lodovico Dolce
Authors: Neri Stefano
Published: July 2021

El artículo, centrado en las adaptaciones italianas en verso del Palmerín y del Primaleón de Lodovico Dolce, prosigue una línea de investigación empezada en trabajos anteriores. Se analizan aquí algunas de las transformaciones que afectan los textos en distintos niveles, desde los originales españoles (1511, 1512) hasta los poemas en octavas de Dolce (1561, 1562), pasando a través de las ediciones venecianas en castellano (1534) y de las traducciones italianas en prosa (1544, 1548). Se aborda, en especial, el estudio de algunos episodios amorosos y bélicos que, evidenciando cambios significativos en la configuración literaria de los textos, contribuye a definir la naturaleza y el alcance de la propuesta de Dolce, combatida entre la voluntad de agradar al lector y la exigencia de arrimarse a los patrones morales tridentinos y a los cánones del poema caballeresco culto.
Lithuanian Catechism for Rural Schools (1795). Circumstances of its Compilation
Authors: Sidabraitė Žavinta
Published: July 2021

Researchers constantly add new items to the bibliography of Lithuanian publications published in East Prussia in the last decade of the 18th century. The initiatives of publishing in local languages of that period were driven by the reforms of the Church and schools carried out by the Prussian authorities while the Enlightenment was coming to an end and the ideo­logy of regional particularism was continuously growing in the country. As can be seen from newly discovered archival documents and already recorded bibliographic information, at least four publications dedicated for primary Christian education were published in Prussia in 1795, namely, the New Testament, the psalm book, the semi-secular reading textbook The Friend of Children (Kūdikių prietelius), and the catechism for rural schools. The editions of the New Testament and Kūdikių prietelius are recorded in the Lithuanian bibliography, however, nothing has been known about the mentioned editions of the psalm book and the catechism so far. The circumstances of their publishing are analysed in the article.
From the History of Book Culture of Ukraine: Research of Retrospective Book, Art, Music Publications and Historical Collections from the Funds of the Vernadsky National Library Of Ukraine
Authors:   Vernadsky National Library of Ukraine, Kovalchuk H.I.
Published: July 2021

The collective monograph is the result of scientific research on the history of book culture of Ukraine, conducted by scientists of the Institute of Bibliology of the Vernadsky National Library Of Ukraine during 2016-2018 on the basis of the funds of the departments of antique prints and rare editions, fine arts, music collections, foreign Ukrainiana, library collections and historical collections of the Library. The history of book culture of Ukraine of the XVI-XX centuries, which appears from the pages of this edition, has a multifaceted, but absolutely reliable character, as it is based on specific sources. For bibliologists, librarians, bibliographers, historians of national culture.
Study of functional elements of control systems
Authors:   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Zabolotnyi P.I. , Gorev N.B. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Gryshkevych O.D. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine, Mamchuk V.M. ,   Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine
Published: July 2021

This paper presents the results of investigations conducted at the Department for Functional Elements of Control Systems of the Institute of Technical Mechanics of the National Academy of Sciences of Ukraine and the State Space Agency of Ukraine over the past five years. The investigations into microwave probe measurements resulted in a two-probe implementation of microwave interferometry for displacement measurement. The possibility of using as few as two probes was demonstrated by analyzing the roots of the equation that relates the magnitude of the unknown complex reflection coefficient to the currents of the semiconductor detectors connected to the probes. To improve the measurement accuracy, methods were developed to do this by accounting for the reflection coefficient of the horn antenna, by changing the operating wavelength according to the measured reflection coefficient, and by compensating the interprobe distance error. The results of development and study of microwave meters of ionospheric plasma parameters are presented. Experimental and computer models of microwave meters of plasma parameters were developed and studied. An experimental and theoretical basis was prepared for the development of meters based on biconical cavities to assess the electron density in a rarefied low-temperature plasma. A novel circuit for a pulse discharge source was designed. The performance characteristics of a magnetron system were studied in the regime of generation of a directed gas and metal ion flow. To provide ion beam focusing, a self-contained anode-layer ion sorce was upgraded. The paper presents the results of development and study of prototype ion-plasma, ion-beam, and combined process devices for auxiliary and main surface strengthening operations and combined strengthening treatment in a single vacuum cycle.
Calculation of the linear coefficient of thermal expansion of multi-element, single-phase metal alloys from the first principles
Authors:   Frantsevich Institute for Problems of Materials Science of the NAS of Ukraine, A.	Khachatrian A.
Published: July 2021

One of the possible ways to calculate the coefficient of thermal expansion is a method based on determining the dependence of the total energy of the electron-ion system on the parameters of the crystal lattice at different temperatures. There is a relationship between the calculated values of the linear coefficients of thermal expansion and the melting point of the material. For metals and multi-element single-phase alloys, the dependence of the function V = α·Tmax on the parameter T/Tmax (α — the linear coefficients of thermal expansion, Tmax — melting point of the material) is obtained from the first principles, which has the same form for all single-phase multi-element metal alloys and is presented analytically. Using the method of pseudopotential and quasiharmonic approximation, the linear coefficients of thermal expansion of multi-element metal alloys are calculated. The temperature dependence of the coefficient of thermal expansion, after approximating the results of the computational experiment, is presented in analytical form. The results were compared with known tabular data. To confirm the reliability of the model, the calculation was performed for a number of pure metals. The consistency of the calculated and experimental data on the coefficient of thermal expansion of single-phase alloys calculated from the first principles is observed. There is a relationship between the calculated values of the linear coefficients of thermal expansion and the melting point of the material. For metals and multi-element single-phase alloys, the dependence of the function V = α·Tmax on the parameter T/ Tmax (α — the linear coefficients of thermal expansion, Tmax — melting point of the material) is obtained from the first principles, which has the same form for all single-phase multi-element metal alloys and is presented analytically. Keywords: Electron-ion system energy, interatomic interaction potential, force constants, quasiharmonic approximation, coefficient of thermal expansion.
ЧИСЕЛЬНИЙ АНАЛІЗ МІЦНОСТІ ТА ВИЗНАЧЕННЯ РУЙНІВНОГО НАВАНТАЖЕННЯ КОНСТРУКЦІЙ РАКЕТНО-КОСМІЧНОЇ ТЕХНІКИ
Authors: Дробенко Богдан , Кушнір Роман , Марчук Михайло
Published: July 2021

Вступ. Проєктування ракетних конструкцій передбачає процес комп'ютерного моделювання їхньої механічної поведінки за умов експлуатації. За кресленнями оптимального проєкту, отриманого в результаті обчислювальних експериментів, виготовляють фізичний прототип, який піддають випробуванням, за результатами успішності яких переходять до виготовлення серійної продукції. Питома вага комп'ютерного моделювання в цьому процесі постійно зростає, позаяк експериментальні дослідження є доволі обмеженими і високовартісними.Проблематика. Оцінки міцності конструкцій істотно залежать від точності й достовірності даних про їхній напружено-деформований стан за умов експлуатації. Тому розроблення програмного забезпечення для оцінювання напружено-деформованого стану конструкцій на основі високоточних математичних моделей є надзвичайно актуальним.Мета. Розроблення методології адекватного дослідження міцності складних конструкцій ракетної техніки за інтенсивних силових навантажень та визначення руйнівних навантажень за результатами комп’ютерного моделювання.Матеріали й методи. За припущення, що переміщення й деформації є великими, а напруження перевищують межупластичності матеріалів, задачу сформульовано в межах геометрично нелінійної теорії термопружно-пластичності.Для її розв’язування використано метод скінченних елементів.Результати. Розроблено методологію дослідження напруженого стану складних конструкцій ракетної техніки заінтенсивних силових навантажень з метою оцінювання руйнівних навантажень таких конструкцій за результатами комп’ютерного моделювання на основі уточнених математичних моделей, яку успішно апробована на Державномупідприємстві «Конструкторське бюро «Південне» ім. М.К. Янгеля» при проєктуванні паливних баків ракети-носія.Висновки. Розроблена методологія дає можливість суттєво скоротити або й взагалі відмовитись від натурних експериментів, під час яких конструкцію доводять до руйнування.
ОЦІНКИ ВИКИДІВ МЕТАНУ В НАФТОГАЗОВІЙ ГАЛУЗІ УКРАЇНИ: ПРОБЛЕМИ ТА СВІТОВИЙ ДОСВІД ЇХ ВИРІШЕННЯ
Authors: Лещенко Ірина
Published: July 2021

Вступ. Враховуючи можливий вплив на майбутнє нафтогазової галузі політичних рішень стосовно декарбонізації економіки, потрібно розробити стратегію її подальшого розвитку з урахуванням необхідності зменшення викидів не тільки двоокису вуглецю, а й метану.Проблематика. Останніми роками у багатьох країнах ведеться активна діяльність зі скорочення викидів метану у нафтогазовій галузі. Для вирішення цієї проблеми сформовано низку національних та міжнародних ініціатив. В Україні зазначеному питанню не приділяється достатньо уваги.
Мета. Проаналізувати стан моніторингу викидів метану від нафтогазової галузі України та узагальнити досвід інших країн з цього питання.Матеріали й методи. Аналіз офіційних даних щодо викидів метану від нафтогазової галузі України; огляд авторитетних літературних джерел та документів міжнародних організацій щодо оцінки викидів метану від підприємств галузі, технологічних та інституціональних заходів, спрямованих на вирішення проблем моніторингу та верифікаціїцих викидів.Результати. Виконано порівняльний аналіз оцінок викидів парникових газів у нафтогазовій галузі відповідно до Національного кадастру парникових газів та річних звітів групи «Нафтогаз України». Розглянуто особливості джерел викидів метану в галузі та проблеми кількісного визначення обсягів його викидів. Проаналізовано технологічні засоби та заходи, які запроваджуються в різних країнах для вирішення проблем моніторингу викидів метану.Висновки. Встановлено, що існує широкий спектр доступних технологій для виявлення та кількісного оцінювання викидів метану в галузі. Визначено необхідність переходу до використання національних коефіцієнтів при формуванні Національного кадастру парникових газів в частині оцінки летучих викидів від діяльності з вуглеводнями. Важливим чинником зменшення викидів метану від галузі має стати політика держави, акцентована на розробленніта запровадженні регуляторних стандартів і спеціальних економічних інструментів.
СПЕКТРОМЕТР-ІДЕНТИФІКАТОР НА ОСНОВІ ТВЕРДОТІЛЬНОГО ДЕТЕКТОРА ДЛЯ ОБ’ЄКТІВ ЯДЕРНО-ПАЛИВНОГО ЦИКЛУ
Authors: Забулонов Юрій , Буртняк Володимир , Одукалець Людмила
Published: July 2021

Вступ. Наслідком аварії на Чорнобильській АЕС стало радіаційне забруднення значної території. З метою запобігання потрапляння радіоактивних елементів в довкілля та продукти харчування необхідним є використання спеціалізованих приладів, що дозволяють здійснювати контроль радіаційної обстановки.Проблематика. Одним з найбільш ефективних способів оперативного виявлення та ідентифікації джерел іонізуючого випромінювання в довкіллі є контроль за розповсюдженням радіонуклідів, присутніх у продуктах харчуваннята будівельних матеріалах.Мета. Розробка сучасного вітчизняного обладнання для автоматизованого оперативного виявлення, ідентифікації та моніторингу джерел іонізуючого випромінювання в середовищі в режимі реального часу.Матеріали й методи. Використано методи математичного та комп’ютерного моделювання, натурного макетування, машинного проєктування. Для дослідження технічних характеристик системи, її особливостей проведено натурнівипробування окремих її каналів в зоні відчуження Чорнобильської АЕС.Результати. Створено та апробовано експериментальну систему автоматизованого оперативного виявлення, ідентифікації та моніторингу джерел іонізуючого випромінювання в навколишньому середовищі в режимі реального часу, а також ідентифікації виявлених радіоактивних ізотопів та достовірної оцінки їхньої активності.Висновки. Створений спектрометр-ідентифікатор є системою швидкого реагування нового покоління на базі сучасних технологій, синтезу принципів радіометрії, спектрометрії та математичного моделювання для ефективного контролю питомої активності рідких, в'язких, сипучих харчових і нехарчових проб, ідентифікації їхнього радіонуклідного складу. Впровадження ідентифікатора-спектрометра сприятиме суттєвому скороченню часу на проведення оперативної масової перевірки харчових і нехарчових проб та ідентифікації їхнього радіонуклідного складу, що, в свою чергу, підвищить рівень екологічної безпеки населення в епоху широкої експлуатації об'єктів ядерно-паливного циклу.
Про діяльність Національної академії наук України в 2020 році та завдання наступного періоду
Authors: Загородній Анатолій Глібович
Published: July 2021

Про діяльність Національної академії наук України в 2020 році та завдання наступного періоду
Про розвиток міжнародного співробітництва в НАН України
Authors: Пріхна Тетяна Олексіївна
Published: July 2021

Про розвиток міжнародного співробітництва в НАН України
Кліматична програма України як основа цілісної екологічної політики держави в умовах зміни клімату
Authors: Осадчий Володимир Іванович
Published: July 2021

Кліматична програма України як основа цілісної екологічної політики держави в умовах зміни клімату
Поверхні — всюдисущі межі поділу різних середовищ
Authors: Наумовець Антон Григорович
Published: July 2021

Поверхні — всюдисущі межі поділу різних середовищ