bluuebunny/crossref_metadata_2025 huggingface dataset:
STUDY ON LEVEL OF ANTI GAD AND ICA AUTOANTIBODIES IN PATIENTSWITH DIABETES MELLITUS
Authors: Phan Thi Minh Phuong , Truong Dinh Thanh
Published: March 2020

Background: Autoantibodies anti GAD and ICA associated to the autoimmune process of patients with diabetes. Detection of these antibodies in progessive diabeticpatients is very necessary because the presence of anti GAD and ICA can predict the progression of the disease to insulin-dependent diabetes in the future. This study was carried out with aims: (1) to define the positive rate, anti GAD and ICA level in patients with diabetes. (2) to evaluate the correlation between anti GAD and ICA with several clinical and paraclinical features of diabetic patients. Materials and method: 88 patients diagnosed of diabetes by the criteria of ADA 2014, withfasting glucose ≥ 126 mg/dL or≥ 7,0 mmol/L) and HbA1C> 6.5%. Indirect enzyme linked immunosorbent assay (ELISA) was used to measure those autoantibodies of anti GAD and ICA, kits were supplied by DRG company, Germany. Results: the anti GAD positive rate was 10.2%; mean of level of anti GAD was 1.44±0.25 U/mL. ICA positive ratewas 9.1%; mean of level of ICA was 1.44±0.12 U/mL. Positive rate with anti GAD and/or ICA was 19.3%. About the correlation between level of anti GAD, ICA with some of clinical features, we found only the statistically significant difference with p<0.05 between blur vision in the group of ICA level > 1.25U/mL with group of ICA level< 1.25U/mL. About the paraclinical features, the difference with statistical significance (p<0.05) of HbA1C>6.5% was found between the group with anti GAD> 1.05U/mLand the one with anti GAD< 1.00U/mLand also betweenthe group of ICA > 1.25 U/mL and ICA < 1.25 U/mL. Key words: autoantibody anti glutamic acid decarboxylase, islet cell autoantibodies, diabetes mellitus.
EFFICACY ON CLINICAL OUTCOMES AND SAFETY OF ENDOVASCULAR THERAPY IN TREATMEN FOR ACUTE ISCHEMIC STROKE
Authors: Nguyen Van Khoi , Le Van Phuoc , Nguyen Huynh Nhat Tuan
Published: March 2020

Objectives: The aim of study was to evaluate the efficacy on clinical outcomes and safety of endovascular therapy in treatment for acute ischemic stroke. Materials and methods: A prospective, interventional uncontrolled study with 14 patients suffering acute ischemic stroke treated by endovascular therapy at Choray hospital from 9/2013 to 9/2015. The efficacy and safety were evaluated by variants: a decrease of NIHSS ≥4 pts; average score of NIHSS, mRS at 24 hours, 30 and 90 days; the rate of intracranial hemorrhage, mortality and procedural complications. Results: The study showed a high percentage of patients having a 4-point decrease of NIHSS at 24 hours, 30 and 90 days (42,8% - 78,5%). There was a significantly clinical improvement about the average score of NIHSS, mRS at 24 hours, 30 and 90 days (p<0.05). The rate of symptomatic and nonsymptomatic intracranial hemorrhage was 7,1% and 21,4%; mortality rate was 21,4%. No complications related to the technique. Conclusion: This study showed endovascular therapy improved the efficacy on clinical outcomes and was safety in treatment of acute ischemic stroke. Key words: Acute ischemic stroke, endovascular therapy, efficacy, safety, clinical outcomes.
ASSESS INSULIN RESISTANCE VIA HOMA AND QUICKI INDEXES IN PATIENTS WITH END STAGE CHRONIC KIDNEY DISEASE ON CONSERVATIVE TREATMENT
Authors: Vo Tam , Phan Nguyen Tu Uyen , Nguyen Thi Loc , Nguyen Thanh Minh
Published: March 2020

Insulin resistance has been recognized as a predictor of cardiovascular mortality in patients with end-stage chronic kidney disease Objective: To assess insulin resistance via HOMA and QUICKI indexes in patients with end – stage CKD on conservative treatment. Materials and Methods: 60 patients, in the end stage chronic kidney disease and treated by conservation treatment at Hue Central Hospital from 06/2014 to 06/2015 and 30 patients as the control group. Study design : a descriptive, and cross-sectional study. Results: the average HOMA and QUICKI indexes are 4.81 ± 4.92 and 0.58 ± 0.14 respectively in the treatment group; 1.45 ± 0.80 and 0.71 ± 0.12 in the control group (p<0.05. The prevalece of insulin resistance in the treatment group, having kidney disorder, is 56.7%, higher than that in control group (23.3%), (p<0.005). The prevalence of high blood pressure, hypercholesterolemia and triglyceridemia is significantly different between ‘insulin-resistant’ group and ‘non insulin-resistant’ group (p<0.05). The frequency of factors causing chronic renal failure, of anemia and proteinuria is not significantly different between ‘insulin-resistant’ group and ‘non insulin-resistant’ group (p>0.05). Conclusions: the prevalence of insulin resistance in treatment group is higher than in the control group. Factors relating to insulin resistance are high blood pressure, cholesterolemia and triglyceridemia Key words: Insulin resistance, the end stage chronic kidney disease, conservation treatment.
PRELIMINARY RESULTS OF APPLICATION OF ERCP IN THE TREATMENT OF SOME PANCREATOBILINARY DISEASES
Authors: Than Trong Long , Le Viet Nho , Le Tan Toan , Truong Quang Huy
Published: March 2020

Background and objectives: ERCP is helpful technique in the diagnosis and treatment of some pancreatobilinary diseases. Purposes of this study are studying clinical characteristics, imaging of patients pancreatobilinary diseases indicated for ERCP as well as treatment results and safety of ERCP in the treatment of some pancreatobilinary diseases. Materials and methods: a observational study of results of ERCP application in the patients with bilinary stones and Oddi sphincter stenosis, pancreatic tumors at Quangnam Central General Hospital from 6/2013 till 5/2015. Results: Among 30 patients selected for study, there are 26 patients with bile duct stones (86.6%), 1 patients with Oddi sphincter stenosis and 1 bile duct stenosis (6.7%) and 2 patients with pancreatic tumors (6.7%). In patients with bile duct stones, 12 patients were complicated by obstructive jaundice. Among them, 11 patients were complicated by bilinary infection (42.3%), 5 patients had hyperamylasemia (19.2%), 2 patients were complicated by acute pancreatitis (7.7%); in patients with Oddi sphincter stenosis and 1 bile duct stenosis, in patients with pancreatic tumors. The complete success rate of stone removing is 81.3% in common bile duct stones. The complete success rate of stone removing is 42.9% in common bile duct stones combined with hepatic duct stones. We can not remove stones in all 3 patients with only hepatic duct stones. The complication rate of ERCP is 13.3%, including 2 acute pancreatitis (6.7%), 2 bleeding (6.7%). Conclusions: Bile duct stones are the commonest pancreatobilinary diseases which were selected for ERCP. ERCP is the safe, effective technique in the treatment of pancreatobilinary diseases. Key words: (Endoscopic Retrograde Cholangio-Pancreatography: ERCP);
RESEARCH ON INFECTION RATE IN KHMER WOMEN IN CHILDBEARING AGE IN CAN THO 2015
Authors: Phan Trung Thuan , Tran Dinh Binh , Dinh Thanh Hue , Dinh Phong Son
Published: March 2020

Objective: Infection genital under tract are an important problem of reproductive health care in the community, especially by living habits, personal hygiene and other environmental. Therefore, the perception of Infection genital under tract in Khmer women is poor, the level of knowledge and education is not high, psychological examines gynaecology or sometimes didn't interested to gynecological inflammation. Methods: Cross-sectional study of 830 Khmer women in Can Tho city. Results: (1) The rate of Infection genital tract under is 42.3%, Cervicitis accounts for 43.0%, followed by 24.5% of vaginitis; inflammation of the vulva 1.4%, combine of three lesion is 6.3%; (2) A high rate of Infection genital tract under in ≤ 20 age group accounts for 57.1%.(3) A high rate of Infection genital tract under is the farming industry groups (accounting for 75.8%). Conclusion: (1) Cervicitis accounts for the highest proportion. (2) Infection genital tract under in ≤ 20 age group for the highest proportion, descending to ≥ 41 age group. (3) The high proportion of Infection genital tract under relates to age group, occupation, place of living. KEYWORDS: Infection genital tract under, Khmer women, Can Tho city...
CORELATION OF ROMA ALGORITHM TO PATHOLOGICAL CHARACTERISTICS AND THE STAGES OF DISEASE IN OVARIAN CANCER
Authors: Dang Huy Hoang , Dang Cong Thuan
Published: March 2020

Ovarian cancer is highly mortality in the gynecological cancers, accounting for 15-20% cancers of the female reproductive tract. Patients with primary ovarian cancer have often detected at later stages. Risk of Ovarian Malignancy Algorithm (ROMA) is used for the purpose of assessing the risk of malignancy for choosing appropriate treatments in ovarian tumors. Howerver, the objective of this study was to examine the correlation of ROMA index with pathological characteristics and the stage of disease in patients with ovarian cancer. The crossing describes study conducted in 34 patients with ovarian cancer at Hue Central Hospital during 31 months. Results showed that average age of ovarian cancer was 51.32 ± 12.51; 64.7% of cases were postmenopausal. Tumor size common was 5-10cm (50%). Ovarian serous carcinoma is the highest percentage (55.9%). Ovarian cancer is often detected at stage III (64.7%) according to the TNM and FIGO classification. The average concentration of CA125 and HE4 increases with stage of disease. ROMA had a sensitivity index higher among postmenopausal patients (95%). We conclude that ROMA index significantly correlated with stages of disease according to the FIGO (r=0,358; p<0,05) and TNM (r=0,345; p<0,05) classification, inversely correlated with histological grades and no correlation with tumor size in ovarian cancer. Key words: ovarian cancer, ROMA, histological grade, disease stage
THE TREATMENT RESULTS OF INTRAVITREAL BEVACIZUMAB ON DIABETIC RETINOPATHY
Authors: Tran Thi Thu Hien , Duong Anh Quan , Phan Van Nam
Published: March 2020

Objective: Research of clinical features in diabetic retinopathy. Evaluation of treatment outcomes diabetic retinopathy by intravitreal Bevacizumab.
Patients and methods: A descriptive prospective clinical intervention non-comparative study on 33 eyes of 17 patients diabetic retinopathy who were treated by intravitreal Bevacizumab from 3/2014 to 6/2015.
Results: Average age: 60.06 ± 13.108 years. Average diabetic duration: 6.145 ± 10.47 years. Average HbA1c: 9.506 ± 3.298%. The average of vision after treatment 3 month, 6 month is greater than before the treatment. The average of central retinal thickness after treatment is lowest at 3 months, then back up again at the 5th, 6th. There is no correlation between visual acuity and retinal thickness measured by OCT center before treatment, after treatment.
Conclusion: Intravitreal Bevacizumab in treatment of diabetic retinopathy improve vision and macular edema after 3 months and gradually stabilize in the following months.

Key words: intravitreal Bevacizumab, diabetic retinopathy
INTERACTIONS OF LEGAL SYSTEMS: MODERN INTERNATIONAL LEGAL DISCOURSES
Authors: TOLSTYKH VLADISLAV , BEZBORODOV YURY , LAZUTIN LEV , KOZHEUROV YAROSLAV
Published: March 2020

Introduction: the article deals with the doctrine of modern international law, international legal integration, international security and international responsibility. The aim – to study the development of international law and the interaction of legal systems.

Methods: comparative legal, formal-legal.

Analysis: there are new forms of expressing scientific positions along with traditional forms. It is connected with Internet technologies. The language of discussion of scientific issues is English now. More attention is paid to scientific and practical problems, less to theoretical ones. There are changes in the methodologies of international law, it becomes a «technology», a process of mechanistic challenge, selection, connection and presentation of a limited set of arguments. International law is a universal means to bring together national legal systems.

Results: It is concluded that the doctrine of international law is not holistic now. The legal convergence is the process of convergence of various legal systems and models of legal regulation by international legal means. More over, there is no effective security system both at the universal or regional levels. International responsibility is developing. Its content is being updated at the expense of WTO law.
CURRENT TRENDS IN CASE LAW ON CROSS-BORDER TAX DISPUTES IN CHINA
Authors: LI NA
Published: March 2020

Introduction: tax disputes in China cover a wide range of relationships and transactions. The number of court decisions is limited, but they allow us to determine a number of trends related to the resolution of tax disputes. In particular, Chinese courts do not take into account the opinion of the Organization for Economic Cooperation and Development (OECD) in resolving such cases. This might be rooted with China’s position to protect the interests of the state as a reflection of it being one of the largest foreign investment recipients in the world. Methods: analysis, comparison, description, interpretation. The subject of the study were the rules of law and decisions of Chinese courts on the resolution of tax disputes, as well as statistical data. Analysis: disputes may most possibly arise from those anti-tax avoidance investigations carried out by Chinese tax authorities. The aggressive approaches that Chinese tax authorities used in interpreting and applying tax treaties might trigger more cross-border tax disputes. And this risk will be exacerbated when tax authorities are pressed to meet the revenue target assigned to them. Results: while aggressive anti-avoidance measures are becoming effective tools for collecting incomes, the number of disputes is growing. As a consequence, the role of the judiciary in the mechanism of legal protection of participants in tax disputes will also increase. It seems that the number of appeals to the courts for the resolution of such cases will increase too.
Research and results from the first four years of the Florida RESTORE Act Centers of Excellence Research Grants Program
Authors: Fetherston-Resch Elizabeth
Published: March 2020

Born of settlements surrounding the Deepwater Horizon oil spill in the Gulf of Mexico, the Florida RESTORE Act Centers of Excellence Program (FLRACEP) is charged with administering approximately $26 million in research grants for Florida over a period of more than 15 years. Centers of Excellence are selected through a competitive, peer-reviewed process which has thus far awarded $4.3 million in grants to 10 Florida researchers investigating different elements of marine fish and wildlife research and long-term fisheries monitoring. The initial 11 FLRACEP research grants produced 48 submitted or planned papers, and supported 63 students. While these outputs are significant, the FLRACEP Centers of Excellence are tackling important issues in coastal and marine research, resource management, and community resilience. The FLRACEP management team and program staff work to ensure effective program administration and research that is responsive to the needs of the state within the eligible RESTORE Act disciplines. While the program has encountered challenges in its early years, focus remains on the opportunity this funding represents.
Uji Ekstrak Etanol Daun Kemangi Terhadap Kadar Glukosa Darah, Dan Gambaran Histopatologi Pankreas Tikus Yang Diinduksi Streptozotocin
Authors: Tandi Joni , Niswatulfahriyati Niswatulfahriyati , Nurmadinah Nurmadinah , Handayani Tien Wahyu
Published: March 2020

Penelitian ini bertujuan menguji ada tidaknya kandungan senyawa metabolit sekunder pada ekstrak etanol daun kemangi,efek penurunan kadar glukosa darah dari ekstrak etanol daun kemangipada tikus putih jantan yang diinduksi streptozotocin.Penelitian ini merupakan penelitian eksperimen laboratorium dengan menggunakan hewan uji sebanyak 30 ekor tikus putih jantan dibagi menjadi 6 kelompok dan tiap kelompok terdiri dari 5 ekor tikus dengan rincian kelompok I sebagai kontrol normal, kelompok II sebagai kontrol negatif yang diberikan suspensi Na-CMC 0,5%, kelompok III sebagai kontrol positif yang diberikan suspensi glibennklamide dan kelompok IV,V,VI sebagai kelompok uji diberikan ekstrak etanol daun keamngi, dengan masing-masing dosis 200 mg/kg BB, 400mg/kg BB dan 800mg/kg BB . Perlakuan diberikan selama 14 hari dan dilakukan pengukuran kadar glukosa darah diukur dengan glukometer pada hari ke-0, 7, 14, 21 dan 28. Data hasil pengujian kadar glukosa darah dan menggunakan uji one way Anova pada tariff kepercayaan 95% kemudian dilanjutkan dengan uji Least Significant Difference (LSD), dan data hasil skoring tingkat kerusakan pankreas dianalisis dengan uji Kruskal-Wallis dilanjutkan dengan uji Mann-Whitney untuk melihat perbedaan antar perlakuan. Hasil penelitian menunjukkan bahwa terdapat senyawa metabolit sekunder pada ekstrak etanol daun kemangi yaitu flavonoid, saponin, dan tanin: pemberian ekstrak etanol daun kemangi memberikan efek menurunkan kadar glukosa darah pada tikus putih yang diinduksi streptozotocin: Hasil penelitian menunjukkan bahwa pengaruh ekstrak etanol daun kemangi yang memberikan hasil yang maksimal untuk menurunkan kadar glukosa darah dan regenerasi jaringan pankreas
Efek Antidiabetes Kombinasi Ekstrak Limbah Kulit Bawang Dayak Dan Limbah Kulit Bawang Merah Pada Mencit Yang Diinduksi Aloksan
Authors: Lolok Nikeherpianti , Rahmat Haidir , Wijayanti Putri Mega
Published: March 2020

Ancaman penyakit Diabetes Mellitus ditengah kehidupan masyarakat menjadi momok  yang  sangat  menakutkan  karena  hampir  setiap  10  detik  di  dunia  orang meninggal akibat komplikasi dari penyakit tersebut. Berbagai macam terapi pengobatan untuk diabetes mellitus sudah dirancang oleh WHO maupun pemerintah Indonesia baik dari terapi dengan penggunaan obat sintetik sampai ke pengobatan yang berbahan dasar herbal. Pengobatan herbal sebagai terapi diabetes secara empiris sudah dilakukan sejak dulu, salah satunya pada tumbuhan umbi bawang  merah  dan  umbi  bawang  dayak  untuk  mengevaluasi  efek antidiabetes dan hasilnya memberikan efek yang signifikan terhadap penurunan kadar gula darah penderita diabetes tipe 2. Tujuan penelitian ini adalah untuk mengetahui efektifitas kombinasi ekstrak limbah kulit bawang dayak dan limbah kulit bawang merah terhadap penurunan gula darah pada mencit yang diinduksikan aloksan. Pengujian efek antidiabetes hewan uji dibagi menjadi 5 kelompok, kelompok 1 untuk uji kontrol negative (Suspensi NaCMC), kelompok 2 untuk kontrol positif (insulin pen), kelompok 3 untuk control diabetes (diberi pakan), kelompok 4 untuk kombinasi ekstrak. Hasil uji diabetes terhadap mencit yang diinduksikan aloksan menunjukan bahwa kombinasi ekstrak limbah kulit bawang dayak dan ekstrak limbah kulit bawang merah secara signifikan mampu menurunkan kadar gula darah dibandingkan dengan kelompok diabetes, namun hasilnya tidak berbeda nyata dengan kelompok kontrol positif.
Action Research Model Canvas - ARMC
Authors: Hoang Anh-Duc
Published: March 2020

Action Research Model Canvas is a practical and systematic template for developing, revising, or extending action research. It is a visual chart with blocks that describe key research components and actions. The model is inspired by the Business Model Canvas, which was initially proposed in 2005 by Alexander Osterwalder.
The Effect of Firm Size, Profitability, Audit Committee, and Other Factors to Firm Value
Authors: Djashan Indra Arifin , Agustinus Yosua
Published: March 2020

Objective – This study aims to identify the effect of firm size, profitability, audit committee and other factors on firm value.
Methodology/Technique – The population in this study are all non-financial companies on the Indonesian Stock Exchange from 2015 to 2017. The research sample of 403 companies was selected using a purposive sampling method with certain criteria so that a total sample of 180 companies was obtained. Data testing techniques using multiple linear regression with a significance level of 5% alpha.
Findings – The results show that firm size has a negative effect on firm value while company growth, profitability, liquidity, tangible fixed assets, audit committee and board size all have a significant effect on firm value. Simultaneously, all independent variables have a positive effect on firm value. The coefficient of determination shows that the effect of the independent variable on the dependent variable is 55.9% and the rest is influenced by other factors.

Type of Paper: Empirical
Keywords: Audit Committee; Firm Value; Company Growth; Profitability; Liquidity; Board Size.

Reference to this paper should be made as follows: Djashan, I.A; Agustinus, Y; 2020. The Effect of Firm Size, Profitability, Audit Committee, and Other Factors to Firm Value, Acc. Fin. Review 5 (1): 22 – 27 https://doi.org/10.35609/afr.2020.5.1(3)
JEL Classification: M41, M42, M49.
Nutrient Composition of the Diet of Junior Students of a Medical University
Authors: Chudinin N.V. , Rakitina I.S. , Dementyev A.A.
Published: March 2020

Our objective was to analyze compliance of macro- and micronutrient contents of the diet of modern first- and second-year medical students with physiological and hygienic recommendations. Materials and methods. We conducted a hygienic study of nutrition enumerating 87 junior students of the Ryazan State Medical University who signed an informed consent to participate in the research. Nutrition and physical activity of the students were monitored during 7 days in March-April 2019 and we analyzed the total of 1,729 meals and 532 daily chronograms. Statistical processing of collected data was conducted in order to check a number of statistical hypotheses; at this, the conditions necessary for the application of selected statistical criteria were observed. Results. According to our data, the median energy deficiency in the diet of a modern first- or second-year medical student was 31.3 (12.6:47.7)%. This was mainly related to the deficiency of carbohydrates (48%) caused by low consumption of polysaccharides. Lack of proteins and fats was 10% and 13.3%, respectively. We revealed imbalance of the diet in vitamin composition, which was characterized by the greatest deficiency of vitamins D, K and beta-carotene (less than 15% of the daily requirement). The diets of female and male students were significantly different in the contents of vitamins A, B1, B2, B9 and niacin (p<0.05). Conclusion. The diet of the junior medical students was imbalanced in macro-and micronutrient composition.
Cardiovascular Disease Risk Factors among Copper Industry Workers of the Sverdlovsk Region
Authors: Konevskikh L.A. , Ladokhina T.T. , Konstantinova E.D. , Astakhova S.G.
Published: March 2020

Introduction. Cardiovascular diseases (CVD) are the leading cause of death in the working-age population including occupational deaths. Materials and methods. We conducted general clinical and biochemical studies among copper industry workers including a complete cholesterol test, blood lead and copper tests, volumetric sphygmography with determination of the cardio-ankle vascular index (CAVI), and ultrasound examination of the carotid arteries with intima-media thickness measurements (IMT). Results. We established that the main cardiovascular disease risk factors among our subjects were smoking (72.2%), different types of obesity (33.3%), total cholesterol levels higher than 4.9 mmol/L (57.9%), fasting hyperglycemia (73.9%), and hypertension stages 1 and 2 (40.7%). We also observed increased arterial stiffness by CAVI in 28.7% of the subjects that became more prevalent with the rise in the total CVD risk by SCORE (p=0.00105). Conclusions. We found correlations between CAVI and blood copper levels (r=0.33), years of exposure to occupational risk factors (r=0.187), and IMT (r=0.41). This finding enabled us to recommend the use of CAVI for identification and follow-up of workers at risk of cardiovascular diseases with a simultaneous decrease in exposures to occupational risk factors.
Effects of Dihydroquercetin on Behavior of Albino Rat Offspring
with Transgenerational Chemical Body Burden
Authors: Kapustina E.A. , Lisetskaya L.G.
Published: March 2020

Introduction. Lead pollution is a common environmental problem. Having no physiological functions, this toxicant has a negative polytropic impact on a body, including neurotoxic, reproductive, and transgenerational effects. The mechanism of lead toxicity is oxidative stress. Flavonoids have active antioxidant properties. They are widely represented in plant foods, are able to restore protective capabilities of cells and have chelating properties with respect to lead. One of the representatives of this group of substances is dihydroquercetin. The objective was to study the effect of dihydroquercetin on behavior of rats with hereditary chemical body burden exposed to lead at 60 mg/kg during 25 days. Materials and methods. We studied the behavior of rat offspring in an open field and established their blood lead levels by electrothermal atomization atomic absorption spectrometry. For statistical processing the U-Mann – Whitney test was used. Results. In the present experiment, the effect of lead on the offspring of male albino rats exposed to 60 mg/kg of lead for 25 days caused changes in the activity of animals in the open field. The severity of changes was more pronounced in animals with a hereditary chemical body burden. These animals showed a decrease in orientation and physical activity and increased anxiety. In rats with a hereditary burden, changes in behavior were detected when administering dihydroquercetin. The activity of animals demonstrated a positive dynamics: we observed a statistically significant increase in physical activity and orientation. The number and duration of behavioral acts approached control values. Conclusions. The revealed effects of lead on the offspring of albino rats with a transgenerational chemical body burden require further study to understand the mechanism of the phenomenon.
Informational Evaluation of Epidemiological Aspects of Prostate Cancer Cases
Among Citizens of Saint Petersburg
Authors: Movchan K.N. , Hizha Val.Vas. , Chernov K.E. , Zharkov A.V. , Artyushin B.S. , Hizha Vit.Val.
Published: March 2020

Introduction. Prostate cancer ranks first among all malignant neoplasms in men. The use of information and
analytical tools in comprehending the results of examining and treating verified prostate cancer cases in St. Petersburg
is important for implementing measures to increase life expectancy and to improve the quality of men’s health. Materials
and methods. We analyzed indicator medical statistics on prostate cancer cases in St. Petersburg in 2013–2017 based on the
municipal population cancer registry data. Results. The results showed that the increase in prostate cancer incidence rates
in the city was not related to poor quality of medical examination or treatment. The latter remained appropriate and was
ensured by the proper level of modernization of technological and organizational methods for providing medical care to
such patients. Successful mastering of innovative information techniques of cancer data analysis by local specialists is one
of the prerequisites for efficient cancer prevention with a full-fledged implementation of actions envisaged by the Russian
Healthcare Development Program. Conclusions. Some quality indicators of St. Petersburg oncology service in terms of
providing medical care to prostate cancer patients are comparable to those in other Russian regions or turn out to the best
in some respects. Targeted measures taken by the City Administration and its Health Department to promote a healthy
lifestyle and to inform the citizens about dangers of prostate cancer yield positive results.
Assessment of Uranium Concentrations in Drinking Water Supply Sources Based on
the Results of Laboratory Analysis of 238U and 234U Specific Activities and Laboratory
Determination of Uranium According to GOST R 54499–2011
Authors: Pivovarova E.A. , Pivovarov A.A. , Kurganov V.E.
Published: March 2020

Introduction. The cause of toxicity and damaging effects of uranium and its compounds on the body lies in radioactivity of uranium isotopes and their decay products as well as their high chemical activity. In view of the above, we conducted parallel studies of specific activities and concentrations of uranium in household and drinking water supply sources. Materials and methods. We studied specific activities of uranium-234 and uranium-238 in the centralized drinking water supply sources of the Republic of Khakassia exceeding control levels in terms of specific total alpha activity (Aα) and converted them to mass concentrations of uranium. Parallel analyses of uranium concentrations in water using the luminescent method according to GOST R 54499–2011 were performed. Results. Our assessment of the radionuclide composition of centralized drinking water supply sources showed that Aα levels exceeding control levels were largely due to natural radionuclides uranium-238 (contribution up to 25%) and uranium-234 (contribution up to 69%). Based on the specific activities of uranium-234 and uranium-238, we estimated masses (concentrations) of uranium in water ranging from 0.007 to 0.06 mg/L depending on the water source. In the parallel tests of water samples according to GOST R 54499–2011, uranium concentrations ranged from 0.007 to 0.061 mg/L. Conclusions. The uranium concentrations in the republican centralized drinking water supply sources estimated on the basis of uranium-234 and uranium-238 specific activities differed from the concentrations of uranium measured by the luminescent method according to GOST R 54499–2011 within the error of the test method. In some settlements uranium concentrations in water exceeded the hygienic standard of 0.015 mg/L (GN 2.1.5.2280–07).
Impact of defects in self-assembled monolayer on humidity sensing by molecular functionalized transistors
Authors: Tanaka Takahisa , Yajima Takeaki , Uchida Ken
Published: March 2020

For highly sensitive and selective sensors, numerical study of transistors functionalized with a defected self-assembled monolayer (SAM) was performed. Adsorption of water molecules on the defected SAM was treated by molecular dynamics (MD) calculations. Based on time dependent atomic positions and charges derived from the MD calculations, carrier concentration and threshold voltage of defected-SAM-functionalized transistors were derived from the Poisson equation. The defects of the SAM caused a penetration of water molecules. Due to a strong polarization of water molecules, the water molecules penetrating the defects were stacked in the same direction. The alignment of the water molecules in the defects generated a large electrical dipole, and the threshold voltage of the transistors were shifted.
SELF CARE PENDERITA TB DALAM MENGURANGI RESIKO PENULARAN PENYAKIT DI PUSKESMAS BARABARAYA MAKASSAR
Authors: Meiharti Priyatna Dewi  , Suarnianti  , Syaipuddin
Published: March 2020

Tuberkulosis (TB) merupakan masalah kesehatan masyarakat di dunia, terutama di negara-negara berkembang termasuk Indonesia. Berbagai macam cara telah dilakukan untuk mengurangi resiko penularan tetapi pravelensi TB paru semakin meningkat dari tahun ke tahun.  Salah satu cara mengurangi resiko penularan penyakit yaitu dengan adanya self care yang baik dari penderita penyakit TB. Terdapat tiga tahap pengurangan resiko penularan yaitu labeling, komitmen dan enactment. Tujuan penelitian ini untuk mengetahui self care penderita TB dalam mengurangi resiko penularan di Puskesmas Barabaraya Makassar. Metode yang digunakan yaitu metode kuantitatif. Hasil analisis statistik menggunakan uji Chi Square menunjukkan nilai (ρ=0,001) dengan demikian nilai ρ lebih kecil dari (ɑ =0,05) (ρ<ɑ). Maka Ha diterima dan Ho ditolak yang berarti ada pengaruh antara self care penderita TB dengan resiko penularan di Puskesmas Barabaraya. Kesimpulan penelitian ini yaitu self care pada penderita TB paru di puskesmas Barabaraya Kota Makassar mayoritas tergolong kurang. Saran bagi penderita TB Paru diharapkan dapat meningkatkan kesadaran untuk mengubah gaya hidupnya menjadi lebih sehat untuk mencegah penularan penyakit TB Paru. Penderita TB Paru juga diharapkan jangan membuang ludah sembarang dan dapat konsisten dalam menjalani proses pengobatan agar penderita TB Paru dapat sembuh total. Pengurangan resiko penularan TB di Wilayah Kerja Puskesmas Barabaraya Kota  Makassar mayoritas tergolong kurang. Ada pengaruh self care penderita TB dalam mengurangi resiko penularan di Puskesmas Barabaraya Makassar.
Numerical Prediction of Wall Pressure Fluctuations in a Turbulent Boundary Layer on a Cylinder in Axial Flow
Authors:   Ramesh Babu S, Department of Mechanical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Srivilliputhur, Tamil Nadu, Arunachalam E , K Karthik ,   Department of Aeronautical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Srivilliputhur, Tamil Nadu, S Jeyakumar ,   Department of Aeronautical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Srivilliputhur, Tamil Nadu
Published: March 2020

Flow noise originating in the turbulent boundary layer (TBL) often severely limits the performance of towed sonar cylinder and therefore it is necessary to predict this noise for the design of efficient towed cylinder. This paper presents large eddy simulation methodology to establish the TBL properties and wall pressure fluctuations on a 3 m long cylinder with length to diameter ratio of 315 in the operating speed of 11.4 m/s in air. The computed flow induced sound is compared with experimental measurement available in the literature successfully. The effectiveness of scaling the flow noise spectra with diameter and tow speed is discussed and non-dimensional wall pressure spectra presented with respect to non-dimensional frequency. The overall sound pressure levels are also compared with experimental data that show good accuracy achieved by the proposed numerical methodology.
Outcomes Based Technique for Measuring Critical Thinking Ability on Computer Science and Engineering Students
Authors:   Research Scholar, NITTTR Chennai, University of Madras, Mathew* Bruce , Sambanthan Dr. T Gnana ,   Retd Professor, NITTTR Chennai
Published: March 2020

Literature clearly indicates that it is possible to develop quantifiable outcomes, such as critical thinking abilities, measure them and communicate student learning achievement of the outcomes, if the instructional and assessment approaches are organized in an effective way. Critical thinking ability of the Computer Science and Engineering students is an active process of skilfully conceptualizing the domain concept, analyzing and evaluating the information. This paper attempts to measure learning outcomes of ‘critical thinking ability’ which might be obtained by the students of Computer Science and Engineering, through two different instructional perspectives namely, i. the traditional linear time-bound instructions and ii. Outcomes Based instructions. The objective of this exercise is to determine whether Outcomes Based Education (OBE) in its instructional principles would be more suitable over the traditional methods in imbibing ‘Critical thinking ability’ as a learning outcome? Is it possible to classify students who prefer OBE methods of instructions? The paper elaborates an experimental study to compare and correlate the results obtained by these two selected instructional principles. The conclusions drawn out of the experimental studies as well as from the survey results will be of immense use to educational researchers of Computer Science and Engineering.
Design of IoT based Garbage Segregation for Automatic Smart Trash Bin using NI LabVIEW
Authors:   ECE, VelTech R.Rangarajan Dr.Sakunthala R&D institute of Science and Technology, Chennai . India., Devi P Kalpana , D Dharini ,   ECE VelTech R.Rangarajan Dr.Sakunthala R&D institute of Science and Technology, India . Chennai .India., Vandhana J Lakshmi ,   Anna University, Chennai India.
Published: March 2020

A Smart Trash Bin segregates wastes by itself as degradable wastes and non-degradable wastes with the help of sensors and motors, interfaced with NI myRIO. Rapid changes in technology, low initial cost and planned obsolescence have resulted in a fast-growing surplus of wastes all around the globe. People dump wastes on roadsides, which is not picked up regularly by the people responsible. It s proposed to separate the wastes into categories like degradable and non-degradable will take place in an effectively closed manner .The entire process of waste input, level and segregation is monitored and controlled by the reconfigurable IO using sensors , thereby reducing the open decomposition of organic wastes, thus curbing the growth of micro organisms.
Thermal Examination of Vapour Absorption System using Experimental Design Method
Authors:   School of Renewable Energy and Efficiency, National Institute of Technology, Kurukshetra, Haryana, India., Solanki A. , Yashpal  ,   Department of Electrical Engineering, National Institute of Technology, Kurukshetra, Haryana, India
Published: March 2020

The experimental investigation has been carried out for 100 kW triple-effect vapor absorption refrigeration systems using parabolic trough collector. The data have been recorded and analyzed for designing a new vapor absorption refrigeration system with process heat for industrial applications for Gurugram regions of India. The solar resources have also been analyzed for designing of the system. The thermodynamic evaluation of 100 kW triple-effect vapor absorption refrigeration systems has analyzed for different parameters. The heat is supplied from solar thermal technology which converts solar radiation to useful heat of the total input energy of the proposed cooling system is taken from the heat transfer fluid through parabolic trough collector (PTC) as per availability of solar insolation at the pressurized water of 140-180 oC supplied to the generator at a mass flow rate of 7 kg/s. It is analyzed that in the month of November radiation drops because of cosine losses as compared to May and Direct Normal Irradiance decreases in the month of December, January, July, August, and September.
Implementation of Peltier Tiles for Heating Jacket
Authors:   Engineering Physics Department, Universitas Nasional, Jakarta, Indonesia, Hidayanti* Fitria , Wati Erna Kusuma ,   Engineering Physics Department, Universitas Nasional, Jakarta, Indonesia., Anwar Risad ,   Engineering Physics Department, Universitas Nasional, Jakarta, Indonesia.
Published: March 2020

Peltier modules or Peltier tiles utilize the Seebeck phenomenon, where a semi-conductor thermocouple material is flanked by 2 plates, if one side is hot and the other side is cold, the module will produce a voltage whose value is proportional to the temperature difference. This effect can be applied in reverse. If the module is electrified, it will produce heat on one side and cold on the other side. Jacket as a heater is applied when the ambient temperature is lower than the body temperature. The temperature of the heating jacket is 53.1 ℃. In the experiment 6000 mAh battery can provide power for Peltier for 35 minutes.
Photonic RF channelizer based on 49GHz soliton crystal microcombs
Authors: Moss David , Morandotti Roberto , Mitchell Arnan , xu xingyuan , tan mengxi , Wu Jiayang
Published: March 2020

We report a broadband radio
frequency (RF) channelizer with up to 92 channels using a coherent microcomb
source. A soliton crystal microcomb, generated by a 49 GHz micro-ring resonator
(MRR), is used as a multi-wavelength source. Due to its ultra-low comb spacing,
up to 92 wavelengths are available in the C band, yielding a broad operation
bandwidth. Another high-Q MRR is employed as a passive optical periodic filter to
slice the RF spectrum with a high resolution of 121.4 MHz. We experimentally
achieve an instantaneous RF operation bandwidth of 8.08 GHz and verify RF
channelization up to 17.55 GHz via thermal tuning. Our approach is a significant
step towards the monolithically integrated photonic RF receivers with reduced
complexity, size, and unprecedented performance, which is important for wide RF
applications ranging from broadband analog signal processing to
digital-compatible signal detection.
Outcome of Single Dose Prophylactic Antibiotic in Carpal Tunnel Release Surgery
Authors: Khan Inayat Ali
Published: March 2020

Background: It has been well documented that administering a prophylactic antibiotic brings down the rate of postoperative wound infection very strikingly in carpal tunnel release (CTR) surgery. Carpal tunnel syndrome (CTS) is definitely a compressive neuropathy of the upper limbs, which is both benign and frequent. The study objective was to determine the postoperative wound infection rate in carpal tunnel release surgery after having administered a single dose of a prophylactic antibiotic.

Methods: This cross-sectional study was carried out at the department of Neurosurgery, Dammam Medical Complex-Saudi Arabia. The study was based on 122 patients who were operated for carpal tunnel release procedures at the centre. Pre-operatively all patients were subjected to nerve conduction studies (NCS) to document CTS as the definitive diagnosis. As a routine, every patient was administered intravenous loading dose of cefuroxime (1.5g) at least 1 hour prior to surgery. All patients were treated as day care cases and were discharged after a few hours of surgery. On discharge, no further antibiotics were administered. Their wounds were examined.

Results: Superficial redness over the site of incision was noted in three of the patients and wound infection in two others. These two patients improved with oral antibiotics. Not a single patient needed re-exploration.

Conclusion: The current study showed that this is an efficacious and a very safe protocol to follow. Assuming the fact that the incidence of surgical site infection (SSI) in CTR surgery is low, the results were not different when compared to the results from other centres.
Frequency of HIV in Patients with Central Nervous System Tuberculosis
Authors: Ashfaq Ahsan
Published: March 2020

Background: Tuberculosis (TB) is the most widely recognized reason for death in patients of acquired immune deficiency syndrome (AIDS). Human Immunodeficiency virus (HIV) and AIDS continue to be on an increase in Pakistan. This study aimed to assess the magnitude of HIV among patients with Central nervous system (CNS) tuberculosis as its progression to AIDS significantly influences mortality in these patients. The main objective of the study was to determine the frequency of HIV among patients with CNS tuberculosis.

Methods: This Cross-Sectional study was conducted at Medicine Wards of Civil Hospital, Karachi from 7th October 2016 to 7th April 2017. A total of 140 newly diagnosed Central Nervous System tuberculosis patients were included. Blood sample collected for HIV test (ELISA) was interpreted as either: Reactive for HIV or Non-reactive for HIV. HIV infection was considered as HIV positive by using 3 Rapid Diagnostic testing kits according to guidelines of World Health Organization (WHO). All the patient data were collected through a pre-designed proforma. Data were analyzed using SPSS v.23.0. Chi-square test was applied post stratification with p- value≤0.05 taken as statistically significant.

Results: Sixteen patients (11.43%) of CNS tuberculosis were found to have HIV positive results. Out of total 140 patients, 50(35.71%) were female and 90(64.29%) were male. The average age of the patients was 39.37±12.8 years.

Conclusion: CNS tuberculosis can be the primary clinical manifestation of HIV positive patients. Early recognizable proof of HIV in patients with CNS tuberculosis may warrant early inception of anti-HIV treatment.
Change in Post Partum Family Planning Behaviour Observed in Pakistani Men and Women in a Squatter Settlement in Karachi: A Pre-Post Observational Study
Authors: Jehangir Fatima
Published: March 2020

Background: Unfortunately, in Pakistan, there are many myths associated with family planning practices hence general reluctant perception of couples is observed especially just after childbirth. In fact, post partum is the most vulnerable period to discuss contraception. In our study, we aimed to see the change in post partum contraceptive behaviours after thorough counselling to individuals in a squatter settlement in Karachi, Pakistan.

Methods: This is a pre-post observational study done from September 1st 2018 until November 15th 2018 in a squatter settlement in Sikanderabad Karachi. A total of 1023 subjects, both males and females of reproductive age group were recruited in the study. The base line knowledge was assessed by using pre-prepared extensive questionnaire adapted from Best Paper Practice (BPP) PPFP (Post Partum Family Planning) Royal College of Obstetrics and Gynaecology (RCOG) about contraceptive behaviours, after taking informed consent and providing privacy. After filling the pre-test forms, an awareness talk describing the advantages and disadvantages of all methods of contraception currently available in Pakistan, was discussed in detail. Data was analyzed using SPSS 20 filled a post-test questionnaire consisting of the same questions. Mc-Nemar’s test was used to see the difference in the pre and post questionnaire. p-value <0.05 was considered significant.

Results: Knowledge of use, side effects and efficacy of all the contraceptive methods was enhanced considerably post session showing statistically significant results (p-value <0.00).
Conclusion: It is clearly seen that giving contraceptive education helped couples to choose the appropriate contraceptive method to give birth spacing.
Genome-wide identification and comprehensive study of anti-fungal genes in chickpea
Authors: Alsamman Alsamman , Mousa Khaled , Nassar Ahmed , Shereif Ghada , Habib Peter , Ibrahim Shafik
Published: March 2020

Chickpea is an important crop that delivers nutritious food to the increasing global community and it will become increasingly popular as a result of climate change. Our objective was to use comprehensive data analysis to locate and identify candidate genes for fungal disease resistance. We used a comprehensive bioinformatics pipeline of sequence alignment, phylogenetic analysis, protein chemical and physical properties assessment and domain structure classification. In order to study gene evolution and genetic diversity, we compared these genes with known anti-fungal genes in different species of plants. A total of 19721 protein sequences belonging to 187 plant species have been downloaded from public databases, including the entire chickpea genome. We have successfully identified 23 potential anti-fungal genes in 10 different chromosomes and genomic scaffolds using sequence alignment and gene annotation. Ca2 and Ca6 have the highest number of genes followed by Ca3 and Ca4. Anti-fungal chickpea proteins have been identified as cysteine-rich (10), thaumatin (6), pathogenesis (4) and plasmodesmata (3) proteins. Analysis of the chemical and physical correlation of anti-fungal proteins revealed a high correlation between different aspects of anti-fungal proteins. Five different pattern patterns have been detected in the anti-fungal chickpea proteins identified, including domain families associated with fungal resistance. The maximum likelihood of phylogenetic analysis was successful in distinguishing between anti-fungal chickpea proteins as seen in their protein patterns/domains.