bluuebunny/crossref_metadata_2025 huggingface dataset:
Upaya Meningkatkan Keterampilan Teknik Dasar Passing Futsal Menggunakan Metode Drill
Authors: Sugiarto Tatok , Tomi Agus , Fauzi Iqbal Anwar
Published: February 2022

Tujuan dari penelitian ini adalah untuk meningkatkan keterampilan teknik dasar passing futsal dengan metode drill pada peserta ekstrakurikuler SMA Negeri 3 Kediri. Metode penelitian yang digunakan adalah metode penelitin tindakan olahraga. Penelitian yang menggunakan jenis penelitian tindakan olahraga ini memiliki kesamaan dengan penelitian tindakan kelas. Prosedur penelitian yang digunakan memiliki kesamaan dengan tahapan dari penelitian tindakan kelas yaitu perencanaan, pelaksanaan, observasi, refleksi. Subjek dalam penelitian ini adalah peserta ekstrakurikuler futsal SMA Negeri 3 Kediri yang ber jumlah 25 orang. Hasil penelitian ini diperoleh dari 25 peserta, dengan rincian 3 minggu pertama untuk siklus 1 dan 3 minggu kedua untuk siklus 2. Hasilnya diperoleh pada minggu terakhir, ditemukan bahwa keterampilan teknik dasar passing peserta ekstrakurikuler futsal SMA Negeri 3 Kediri mengalami peningkatan. Tingkat keberhasilannya sudah mencapai kriteria ketuntasan kategori baik dengan persentase sebesar 83 persen.
Survei Kondisi Fisik Atlet Pencak Silat Persaudaraan Setia Hati Terate
Authors: Arifin Agus , Amiq Fahrial , Fitriady Gema
Published: February 2022

Abstract: This study aims to determine the physical condition of the athletes of the UKM PSHT UM pencak silat. The physical components measured were arm muscle strength, abdominal muscle strength, leg muscle strength, agility, and cardiovascular endurance. The research method used is descriptive quantitative research method with survey technique design. The subjects in this study were 27 athletes of the UKM PSHT UM pencak silat, consisting of 21 male athletes and 6 female athletes. The results of the physical condition of the male athletes obtained arm muscle strength in the "moderate" category of the pull test, the "moderate" category of the push test. The average abdominal muscle strength was in the "Fair" category. The muscle strength of the legs averaged the “Fair” category. Agility is “Average” category average. Heart-lung endurance averaged in the “Fair” category. The physical condition of female athletes obtained the average arm muscle strength results in the "moderate" category, the average push test was in the "moderate" category. "Moderate" category average abdominal muscle strength. The muscle strength of the legs averaged the “Fair” category. “Below average” category average agility. Heart-lung endurance averaged in the "Moderate" category. Based on the research results, it can be concluded that the physical condition of the athletes of UKM PSHT UM is not in the good or excellent category. 
Abstrak: Penelitian ini bertujuan untuk mengetahui kondisi fisik atlet pencak silat UKM PSHT UM. Komponen fisik yang diukur adalah kekuatan otot lengan, kekuatan otot perut, kekuatan otot tungkai, kelincahan, dan daya tahan jantung paru. Metode penelitian yang digunakan adalah metode penelitian deskriptif kuantitatif dengan rancangan teknik survei. Subjek dalam penelitian ini adalah atlet pencak silat UKM PSHT UM yang berjumlah 27 atlet, terdiri dari 21 atlet laki-laki dan 6 atlet perempuan. Hasil kondisi fisik atlet laki-laki memperoleh kekuatan otot lengan tes pull kategori “Sedang”, tes push kategori “Sedang”. Kekuatan otot perut rata-rata kategori “Cukup”. Kekutan otot tungkai rata-rata kategori “Cukup”. Kelincahan rata-rata kategori “Rata-rata”. Daya tahan jantung paru rata-rata kategori “Cukup”. Kondisi fisik atlet perempuan memperoleh hasil kekuatan otot lengan tes pull rata-rata masuk kategori “Sedang”, tes push rata-rata kategori “Sedang”. Kekuatan otot perut rata-rata kategori “Sedang”. Kekutan otot tungkai rata-rata kategori “Cukup”. Kelincahan rata-rata kategori “Di bawah rata-rata”. Daya tahan jantung paru rata-rata kategori “Sedang”. Berdasarkan hasil penelitian dapat disimpulkan bahwa kondisi fisik atlet UKM PSHT UM tidak ada yang masuk kategori baik atau excellent.
The possibilities of using beta-blocker bisoprolol in patients with stable angina with concomitant bronchial asthma
Authors: Grigorieva N. Yu. , Ilushina T. P. , Kolosova K. S.
Published: February 2022

Aim    To compare efficacy and safety of treatments with the calcium antagonist (CA) verapamil, the cardioselective β-blocker (BB) bisoprolol, and a combination therapy with bisoprolol and amlodipine in patients with stable angina (SA) with concurrent mild and moderate, persistent bronchial asthma (BA). Material and methods    This open, prospective, randomized, comparative study included 120 patients with an IHD+BA comorbidity. Of these patients, 60 had mild persistent BA and 60 had moderate persistent BA. Each group was divided into 3 subgroup, each including 20 patients, based on the used regimen of antianginal therapy. Stepwise dose titration was performed every 2 weeks (subgroup 1 received the BB bisoprolol 2.5 mg – 5 mg – 10 mg; subgroup 2 received the CA verapamil 240 mg – 240 mg – 240 mg; subgroup 3 received bisoprolol 2.5 mg followed by the combination treatment with bisoprolol and amlodipine as a fixed combination 5+5 mg). All patients underwent a complete clinical and instrumental examination at baseline and at 2, 4, and 6 weeks of treatment. The antianginal effectivity and the effect on bronchial patency were evaluated. Results    In patients with SA and mild persistent BA, the study of external respiration function (ERF) at 2, 4, and 6 weeks of treatment did not detect any significant difference in the forced expiratory volume in 1 second (FEV1) between the treatment subgroups. In patients with SA and moderate persistent BA receiving the treatment, a significant decrease in FEV1 (р=0.022) was observed in subgroup 1 receiving bisoprolol 10 mg at 6 weeks of treatment. In subgroups 2 and 3 during the treatment, significant differences were absent. In patients with SA and mild or moderate persistent BA, the heart rate was significantly decreased in all three subgroups; however, in subgroup 2 receiving verapamil, the changes were considerably smaller than in other subgroups.Conclusion    The study results showed that the BB bisoprolol with dose titration every two weeks from 2.5 to 10 mg or the combination treatment with the BB bisoprolol and the CA amlodipine can be used as the antianginal therapy in patients with SA and mild persistent BA. The BB bisoprolol may be used in patients with SA and moderate persistent BA as the antianginal therapy, but only at doses not exceeding 5 mg to avoid the development of bronchial obstruction. The combination therapy with the BB bisoprolol 5 mg and the CA amlodipine 5 mg is indicated to enhance antianginal and vasoprotective effects.
Predictors of atrial fibrillation in patients with ischemic stroke of undetermined etiology
Authors: Rakhimova I. R. , Khaibullin T. N. , Kovalchuk V. V. , Semenova Yu. M. , Abdrakhmanov A. S.
Published: February 2022

Aim    To identify a complex of predictors and to create a mathematical model for prognosis of atrial fibrillation (AF) in patients with ischemic stroke of undetermined etiology. Material and methods    The study included 981 patients with ischemic stroke. Effects of the following factors were evaluated: gender, a history of stroke, a history of thromboembolism, presence of diabetes mellitus, grade of arterial hypertension, functional class (FC) of chronic heart failure (CHF), age, data of blood biochemistry, and data of coagulogram. The prognostic model was constructed using the binary logistic regression. The value of area under the ROC curve for the proposed prognostic model was calculated.Results    The main predictors of AF in patients with ischemic stroke of undetermined etiology were CHF FC, a history of stroke, age, gender, values of cholesterol and prothrombin index, which were included into the final prognostic model. The sensitivity of the developed model was 83.5 % and the specificity was 85.5 %. The area under the ROC curve corresponding to the interrelation between the prognosis of AF and the regression function value was 0.921±0.012 with 95 % confidence interval: 0.898–0.944.Conclusion    According to the results of the study, the probability of AF in patients with ischemic stroke increased with CHF progression, recurrent stroke, older age, female gender, and reduced prothrombin index and cholesterol level.
Atrial fibrillation and cognitive impairment: features of the relationship, developmental and prevention mechanisms
Authors: Kovaleva A. Ya. , Lukinov V. L. , Lifshits G. I.
Published: February 2022

The article discusses the development of cognitive deficit in patients with atrial fibrillation (AF) and provides data on mechanisms of the development of cognitive disorders in AF. Under discussion are a possibility of reducing the risk of cognitive disorders with the anticoagulant therapy for prevention of stroke in AF and different properties of different anticoagulants, which may be important for patients. Thus, patients with cognitive disorders are more prone to missing the dose, which may entail serious, possibly fatal consequences. Therefore, the convenience of dosing may be essential. The drug rivaroxaban that has once-a-day dosing schedule and a calendar package, may help the patient better adhere to the doctor’s recommendations. Therefore, rivaroxaban may help improving the compliance, which is the major condition for comprehensive, necessary protection of an elderly patient with AF, including the protection, with high safety, from stroke, from the risk of coronary complications, and from the impairment of kidney function.
Possible pathway for heart failure with preserved ejection fraction prevention and treatment: the angiotensin-converting enzyme inhibitor effect on endothelial function in comorbid patients
Authors: Safonova Ju. I. , Kozhevnikova M. V. , Danilogorskaya Yu. A. , Zheleznykh E. A. , Ilgisonis I. S. , Privalova E. V. , Khabarova N. V. , Belenkov Yu. N.
Published: February 2022

Aim      To evaluate the effect of perindopril on the endothelial function and levels of endothelial dysfunction markers in groups of patients with heart failure with preserved (HFpEF) and mid-range (intermediate) left ventricular ejection fraction (HFmrEF).

Material and methods  40 patients with HFpEF (n=20) and HFmrEF (n=20) were evaluated. At baseline, parameters of the morpho-functional state of large blood vessels and of microvessels were evaluated with photoplethysmography, and levels of E-selectin and endothelin-1 (ET-1) were measured. The patients were prescribed perindopril, and after 12 months of treatment, photoplethysmographic parameters and endothelial dysfunction markers were determined again.

Results After 12 months of the perindopril treatment, improvements in the endothelial function of both large blood vessels and microvessels were noted. The phase shift increased from 10.1 to 10.9 ms in the HFpEF group (р=0.001) and from 8.35 to 9.65 ms in the HFmrEF group (р=0.002). Furthermore, the occlusion index increased from 1.45 to 1.75 in patients with HFpEF (р=0.004) and from 1.5 to 1.75 in patients with HFmrEF (р=0.010). The Е-selectin concentration decreased in both groups, from 57.25 to 42.4 ng/ml (р=0.00008) and from 40.5 to 35.7 ng/ml (р=0.010) in patients with HFpEF and HFmrEF, respectively. The ET-1 concentration decreased from pg/ml (р=0.010) in patients with HFpEF whereas in patients with HFmrEF, there was no significant change in the ET-1 concentration after 12 months of the perindopril treatment.

Conclusion      At 12 months, the endothelial function improved and E-selectin and ET-1 levels decreased in patients with HFpEF and HFmrEF.
Fundamentals of age-related and functional digital pulse diagnostics
Authors: Yavelov I.S. , Rochagov A.V.
Published: February 2022

The development of a matrix pulse wave (PW) analyzer becamea reality thanks to the implementation of a 3-point PW sensorin 2017, when the test results of the mock-up sample were published.Later, a mobile medical device, which was given provisionalname the Pranayama Gadget, was designed and developed byour research team. It is the first mobile medical device capableof tracing undistorted PW of the radial artery.Our article presents some algorithms for processing the PWsignal, based on the authors long-term research in the field ofmeasurement and analysis of the PW signals. In particular, a bigrole in the development of this discipline is played by the newspline base of PW reference patterns that forms the basis forthe digital pulse diagnostics.
Study of the effect made by interval hypoxic training on cardiac metabolism and hemodynamics
Authors: Voronina T. , Bersenev E.Y. , Stepanova G.P. , Pyatenko V.V. , Berseneva I.А. , Chernov N.N. , Smekalkina L.V. , Yuldashev B.А. , Murodova M.D.
Published: February 2022

In this study, the Go2Altitude hypoxicator pro- duced by the Australian company BiotechMed was used [1]. A 60-year-old male patient, height 182 cm, weight 95 kg, was fed in alternating mode, 5 minutes / 3 minutes, a mixture of oxygen 12% and nitrogen 88% through a mask, with room air (approximately 20.9% oxygen and 79.1% nitrogen) during the 45-minute session. Figure 1 given herein shows the ECG and rheogram curves recorded before and after exposure to interval hypoxic training (IHT).
Analgesic efficacy of preoperative single dose intravenous dexamethasone in pediatric tonsillectomies by either sharp snare dissection technique or laser technique: A randomised controlled trial
Authors: Naik Dinesh , Jyothi B  , Kirthika G
Published: February 2022

This study was designed to evaluate the postoperative analgesic efficacy of intravenous dexamethasone, and also to determine the postoperative rescue analgesic consumption, morbidity with respect to surgical technique, quality of oral intake, incidence of postoperative nausea and vomiting (PONV), and discharge from hospital.

After ethical committee clearance, a prospective randomized double blind study was planned for one year period on 100 pediatric patients, with5-12 years of age, American Society of Anesthesiologists physical class I and II, undergoing elective tonsillectomy with or without adenoidectomy under general anesthesia were included in the study. Patients were randomly allocated into 4 groups and received the study drug intravenously 10 minutes before induction of anesthesia. Group A undergoing sharp snare dissection tonsillectomy received 0.9% normal saline 50ml, group B sharp snare dissection tonsillectomy received dexamethasone 0.15mg/kg diluted in 0.9% normal saline, group C laser tonsillectomy received 0.9% normal saline 50 ml, group D laser tonsillectomy received dexamethasone 0.15mg/kg diluted in 0.9% normal saline.

We observed statistically significant difference in mean pain scores (p<0.05) between dexamethasone group (group B and D) and control group (group A and C) measured by KruskalWallis analysis of Variance test with less pain in dexamethasone group.

Single dose intravenous administration of dexamethasone (0.15mg/kg) resulted in reduction of post-operative pain, need for rescue analgesics, reduced incidence of PONV, early return to normal diet and discharge from the hospital.
A retrospective study of the effect of dexmedetomidine infusion in cochlear implant surgery among pediatric patients
Authors: Patel Vishwal I , Dhedhi Darshna , Pandya Komal , Sharma Gaurav , Patel Richa
Published: February 2022

Cochlear implantation surgery is usually performed in paediatric patient of 1 to 7 years of age with congenital deaf-mutism. Good results in this surgery are obtained by providing bloodless surgical field with controlled hypotension and postoperative smooth outcome. To anaesthetize these patients, we are using Inj Propofol, Inj fentanyl, Sevoflurane, Dexmedetomidine infusion and muscle relaxants. Dexmedetomidine is an active isomer of medetomidine and an agonist at α2 –adreno receptors. Medetomidine provides perioperative sedation and analgesia thus decreasing other general anaesthetic drug requirement, reduced postoperative pain score, postoperative delirium and other complications.

To determine that inj. Dexmedetomidine infusion is a suitable agent for haemodynamic stability, decreases need of other general anesthetic drug requirement intraoperatively and improves post-operative outcome in cochlear implant surgery.

This study was conducted at a rural tertiary care center, which included 100 samples of pediatric patients (1-7 years of age group) who went through cochlear implant surgeries in last 3 years.

Among all patients, heart rate (HR) remained stable and there was no significant difference between baseline HR and intra-op HR (P=0.3098). The systolic blood pressure (SBP) was decreased significantly compared to baseline reading (P value < 0.0001), but the diastolic blood pressure was not decreased significantly (P= 0.0612).

Dexmedetomidine provides stable haemodynamics, acceptable hypotensive state, good surgical field and excellent analgesia in pediatric patients undergoing cochlear implant surgery.
Pericapsular Nerve Group (PENG) block with bupivacaine for relieving pain during positioning for spinal anaesthesia in 4 patients during hip fracture surgery - A case series
Authors: Sharma Anita , Rana Shelly , Ranaut Aditi , Thakur Nidhi
Published: February 2022

Pericapsular nerve group (PENG) block is a novel approach for providing peri-operative analgesia wherein the articular branches of femoral nerve, obturator nerve and accessory obturator nerve are blocked. It has been found to be very effective as a regional anaesthesia technique during hip surgeries. We, hereby evaluated the USG guided PENG block with 0.25% bupivacaine (20ml) in 4 patients scheduled to undergo hip fracture surgeries. There was significant reduction in the pain scores both at resting position and 15 degree leg raise after the institution of block in all patients. All patients could sit upright during the institution of spinal anaesthesia.
Subarachnoid haemorrhage following spinal anaesthesia– A dreaded complication
Authors: Chandra Alka , Gupta Dheeraj , Dang Aashish , Chand Shri Krishan
Published: February 2022

We present a female patient posted for fixation of fracture femur under subarachnoid block. After spinal anaesthesia she developed hypotension and cardiac arrest. Subarachnoid haemorrhage was diagnosed by CT scan of head when she did not regain the consciousness. Inspite of all the efforts she had a fatal outcome. We discuss the probable causes of subarachnoid haemorrhage after a simple procedure like spinal anaesthesia with an unusual presentation.
Management of a case of parathyroid adenoma- An anaesthetic challenge
Authors: Sethuraman Geeta , Pahuja Heena D , Deshmukh Shubhada , Bhure Anjali R , Chauhan Savita
Published: February 2022

Calcium plays a major role in a number of physiological actions. Primary hyperparathyroidism is the most common cause of hypercalcaemia. Many patients with primary hyperparathyroidism are asymptomatic. Parathyroidectomy is the definitive treatment for primary hyperparathyroidism. We present the successful anaesthetic management of a patient with primary hyperparathyroidism and discuss the anaesthetic issues involved.
Anaesthetic management for a patient with Eisenmengers syndrome undergoing ovarian cystectomy
Authors: Chaudhuri Amartya , Panjwani Shefali , Kulkarni Vinaya , Pandit Savita
Published: February 2022

Eisenmenger's syndrome is a cyanotic congenital heart disease, where septal defects or patent ductus arteriosus advances to pulmonary hypertension with reversed/ bidirectional shunt. Any condition that lowers systemic vascular resistance, increases the degree of right to left shunt and the risk for the patient. Case Presentation: We report anaesthetic management of a 25-year-old P2L2 Female weighing 50kg with Eisenmenger's syndrome presented with an 8.3cm×7.5cm×8.4cm right ovarian cyst posted for ovarian cystectomy.

The procedure was done under epidural anaesthesia, & post-operatively epidural analgesia was administered for 48 hours. After removal of epidural catheter, multimodal analgesia and anticoagulant therapy with Low Molecular Weight Heparin (LMWH)5000 IU by subcutaneous route was initiated.

The mainstay of anaesthetic management in Eisenmenger's syndrome revolves around providing analgesia without decreasing systemic vascular resistance, or increasing pulmonary vascular resistance. Other concerns are hypercoagulable state, global hypoxia, Volume overload, hypercarbia, acidosis, hypovolemia.

Systemic hypotension and increased pulmonary resistance associated with General Anaesthesia, & marked sympathectomy associated with spinal anaesthesia make both these modes of anaesthesia relatively risky compared to the plain epidural. Other concerns addressed during perioperative management were Oxygen support, early thromboprophylaxis, infective endocarditis prophylaxis, fluid restriction, and correction of acidosis.
Non Typhoidal Salmonellae and its aetiological spectrum-An overview with Indian perspective
Authors: Antony Beena
Published: February 2022

Non Typhoidal Salmonellae (NTS) is emerging as a major health problem. NTS serovars have a wide variety of host range varying from domestic animals, aquatic fauna, reptiles, arthropods, leafy vegetables and many more. This zoonotic infection manifests as self limited gastroenteritis associated with food poisoning to fatal extra intestinal invasive infections.

In this overview, an attempt is made to compile the documented reports due to NTS from Indian subcontinent for the last 5 decades, searching the available databases. These reports emphasizes the role of NTS in diverse clinical infections and the possible links of transmission.

Prophylactic measures such as adoption of quality measures in fish and meat processing units, vaccination of farm animals, serotyping of all NTS strains, above all health education and public awareness program should be made mandatory to minimize the incidence of NTS in our country.
Multidrug resistant Acinetobacter baumannii causing Ventilator associated respiratory infections at a tertiary care center of India
Authors: Kakati Barnali , Koul Nupur , Agarwal Sonika , Mittal Garima
Published: February 2022

A rise in Multidrug resistant causing ventilator-associated respiratory infections (VARIs) is posing a therapeutic challenge for physicians and diagnosticians worldwide. Timely detection and reporting of these robust multidrug resistant (MDR) pathogens would be useful in not only guiding an appropriate empirical therapy but also in controlling the spread of these drug resistant strains in the ICUs and hospital.

: To detect in Endotracheal secretions of suspected cases of Ventilator-associated respiratory infections (VARIs) and report the antimicrobial sensitivity pattern for the same.

: Observational study conducted for a one year period in Department of Microbiology and ICU of tertiary care center for all suspected cases of VARIs above age of 18 years.

: The study showed that out of the 131 endotracheal samples received from suspected cases of VARI, was isolated among 29.6% (45). Monomicrobial growth was found in 39 and Polymicrobial growth in 6 samples. Almost all isolates were found to be multidrug resistant. Drug resistance was found against Penicillin, Cephalosporins, Piperacillin-tazobactam and Fluroquinolones. These MDR pathogens were found sensitive to Tigecycline (26%), Tetracycline (16%) and Ampicillin-sulbactam (11%).

: MDR is a rising nosocomial pathogen commonly isolated from critically ill mechanically ventilated patients, timely detection of the same and reporting the drug sensitivity would ensure starting of an appropriate empirical therapy for management and a better prognosis for the patient.
Study of rise in cases of mucormycosis during covid-19 pandemic
Authors: Joshi Pankaj A , Tissopi Subhadra , Shikhare Vishakha , Ramteerthakar Meena , Kulkarni Vanita A
Published: February 2022

There are reports of the rise of Rhino-orbital mucormycosis in COVID-19 patients during the second wave of the COVID-19 pandemic in India. Mucormycosis developed in patients who had the history of COVID-19 infection, uncontrolled diabetes mellitus with associated co-morbidities like hypertension, bilateral pneumonia, ischemic heart disease and concurrent use of steroids and oxygen therapy. So, to understand the association of mucormycosis with COVID-19 and other co-morbidities, we conducted a systemic study of mucormycosis in people with COVID-19.

Tissue samples of patients, clinically and radiologically suspected of mucormycosis, received in microbiology department were examined by KOH mount microscopically and cultured on SDA. The culture isolates were then subjected to lactophenol cotton blue for identification.

A total of 35(72.91%) samples were positive for fungal filaments in either KOH mount or fungal growth on SDA. spp. was most commonly isolated in culture, followed by spp. Mucormycosis was predominantly seen in males, 37(77.08%), than in females, 11(22.91%). The commonest risk factors associated with mucormycosis were COVID-19 positivity 42(87.5%) and diabetes mellitus 41(85.41%).

: To reduce the risk of fungal infection, all efforts should be made to maintain blood glucose levels under control and judicious use of corticosteroids in patients with COVID-19.
Phenotypic characterization of Acinetobacter species and their resistance pattern in a tertiary care hospital
Authors: Bhatawadekar Sunita M , Ravan Teimoor Roshan , Modak Meera S
Published: February 2022

is an emerging opportunistic pathogen and increasingly implicated in hospital acquired infection especially in intensive care unit. The infection caused by spp. is difficult to control due to multi drug resistance which limits its therapeutic options. This study was undertaken to isolate from various clinical samples and to speciate isolates. Efforts were made to study the antimicrobial susceptibility pattern of species and to detect metallo beta lactamase producing strains.

Clinical samples blood, urine, sputum, pus, body fluids and ETT sample received in microbiology laboratory were processed according to the standard laboratory procedure. Identification and antimicrobial susceptibility testing was done by VITEK-2 automated method. All the isolates that showed resistance to Imipenem were tested for Metallo – Beta – Lactamase (MBL) production by phenotypic test, Imipenem-EDTA-combined disc test method.

Out of total 100 spp isolated from clinical samples, 80 were isolated from critical care units. baumannii was common spp 88 (88%), followed by A.complex 10 (10%). Isolation rate of species was highest from blood (27%) specimens followed by ETT (19%). 44% strains of were isolated from respiratory samples. 84(84%) spp, were carbapenem resistant. Out of 84 carbapenems resistant strains 48 (57%) were MBL positive strains by combined disc test.

Emergence of MBLs producing strains of is alarming and reflects excessive use of carbapenems. Therefore early detection and prompt infection control measures is important to prevent further spread of MBLs to other Gram negative bacilli.
Rescatando lecciones aprendidas en proyectos de desarrollo: más que un libro de historias, una plataforma de conocimiento
Authors: Gómez Osorio Andrés , García Ferro Luz Ángela , Zepeda David , Larrota Rojas Dan Esteban
Published: February 2022

Un proyecto de catastro rural que no avanzaba, estudiantes con discapacidad que se quedaron sin clases presenciales por cuenta de la pandemia, obras de infraestructura que debían realizarse en un barrio donde opera la Mara Salvatrucha Estos son algunos de los ocho casos finalistas de Superhéroes del Desarrollo en su edición del año 2021, iniciativa que desde 2018 premia y visibiliza a unidades ejecutoras que logran superar grandes desafíos en la implementación de proyectos financiados por el BID. En la cuarta versión de este evento anual se introdujo una novedad: la convocatoria no solo se dirigió a iniciativas en ejecución, sino también a aquellas concluidas en años recientes, con el propósito de empezar a rescatar buenas prácticas y lecciones de proyectos ya finalizados. Con tal ajuste, Superhéroes del Desarrollo sigue evolucionando para que, más allá de un concurso, se consolide como una plataforma de conocimiento que sea fuente de aprendizaje para otros proyectos de desarrollo en América Latina y el Caribe.
Relationship Between Intelligence and Complex Motor Skills in Children With and Without Developmental Dyslexia
Authors: Borkowska Aneta R.
Published: February 2022

The study investigates the relation between developmental dyslexia, IQ and complex motor skills involving some cognitive and executive functions. The mechanisms underlying the co-existence of disabilities related to reading and writing on the one hand and motor skills on the other hand, still need to be clarified. In the current study it was hypothesised that the level of intelligence may contribute to complex motor skills in dyslexia. The study involved 58 students with developmental dyslexia (age 9.08 yrs; SD = .06) and 50 students constituting a control group (age 9.09 yrs; SD = .06). The measurements were performed using WISC-R, two subtests from the Dyslexia 3 Test, and four complex motor tasks. Children with dyslexia present problems in complex motor tasks, which involved learning of movement sequences and mental rotation. This finding may support the cerebellar deficit hypothesis in dyslexia. Complex motor skills are significantly related to children’s intelligence level or to the interaction of intelligence and dyslexia. Child’s intelligence explains from 7.5% to 35% of the variance in complex motor skills.
Work Attitude, Work Skills, and Core Competencies of Employee in Maintaining Business Sustainability of LPD Bali Province
Authors: Ngurah Gede Sadiartha Anak Agung
Published: February 2022

Human Resources (HR) is the most important production factor to be managed among other production factors. this is due to many factors, both internal and external that will affect the attitudes and behaviors of employees at work. all that is the responsibility of the HR management section in managing company HR so that they can work as the company desires. In connection with this, the author conducted research at LPD Bali Province. The purpose of this research is to assess the work attitudes, work skills, and core competencies of employees in maintaining the business sustainability of LPD Bali Province. The method used in this research is the descriptive-analytical method, which is a method that describes the condition of the company based on facts or events in the company by collecting, compiling, classifying, analyzing, interpreting such data, then an analysis is carried out in order to produce a conclusion and suggestions. Questionnaire calculation results processed using the SMART-PLS Program application obtained experience level of project manager had a strong and significant influence on leadership quality of project manager with partial mediation of coaching style, experience level project manager had a strong and significant influence on coaching style of project manager, coaching style of project manager had a strong and significant influence on leadership quality of project manager, experience level project manager had a strong and significant influence on productivity with partial mediation of project manager coaching style and leadership quality, coaching style of project manager had a strong and significant influence on employee productivity with partial mediation of good project manager leadership quality, good leadership quality of project manager had a strong and significant influence on employee productivity.
A Comparative Study of the Effect of "Self-Awareness" on the Absorption Law in the Qur'an and Psychology
Authors: Sadeghi Masoumeh , Safari Ali
Published: February 2022

The present comparative study argues that although self-awareness in the Qur'anic concepts and psychology has a significant effect on attracting individual and social success; But reaching the final perfection and turning the real self into the ideal self that God expects from the divine caliph; It is quite different from the mental imagery and components of the so-called absorption law and cannot be considered as Allah power for the mind. so, a library study of this article proves that this self-awareness cannot be considered scientifically in the workshops as an introduction to the absorption law. Hence, those who practice self-analysis in the light of reason and following revelation will never suffer harm or failure. Rather, this position will be considered the ultimate goal of creation and the sheer success of a perfect human being.
Implementation of the Principle of Balance in the Sale and Buy Agreement of Households in Waarmeking by Notary in Banda Aceh City
Authors: Syamsuddin Khairunnisa Icha , Yani Teuku Ahmad , Darmawan Darmawan
Published: February 2022

Article 1313 of the Civil Code states that an agreement is an act whereby one or more people bind themselves to one or more other people. One example of a form of agreement is a house sale and purchase agreement. In the process of making a house sale and purchase agreement, the parties must apply the principles of contract law and also the principle of balance to achieve justice in an agreement that is made. So to protect the parties in the home sale transaction activity, it is necessary to have an agreement deed drawn up by the parties which is then recorded and registered in a notary called waarmerking. The purpose of this study is to determine and explain the application of the principle of balance to the sale and purchase of a house that is waarmeking by a notary in the city of Banda Aceh and the legal consequences of the sale and purchase of a house that is waarmeking by a notary in the city of Banda Aceh but does not apply the principle of balance. This type of research used in this research is empirical legal research with a statutory approach (Statute Approach). The results showed that the implementation of the principle of balance in the warmerking house sale and purchase agreement by the notary in its implementation has not gone well. The legal consequence of the House Sale and Purchase Agreement which was waarmeking by a notary in Banda Aceh City but did not apply the principle of balance, then one of the parties was disadvantaged.
Danger and Security: History and Present
Authors: Ravshanov Fazliddin Ravshanovich , Azimov Habibullo Yakubovich
Published: February 2022

This article focuses on the theoretical analysis of changes in the content of the concept of risk and security, the expression of the concept of security in international relations, the concept of risk and security in historical processes, which has a long history. The article analyzes a number of modern approaches to these two concepts from a scientific point of view, focusing on the underlying causes, including the transition of military threats to a secondary basis in the system of these bases, the impact of conflicts in practice.
Critique of Yusuf Haddad's Doubts About the Existence of Contradictions in the Verses of the Qur'an
Authors: Abbasi Nia Saeed
Published: February 2022

One of the miraculous aspects of the Qur'an that has been considered by thinkers since the beginning of Islam is its miracle in the guise of difference and the absence of contradiction. Due to a superficial analysis of the contents of the verses and the lack of correct principles and rules in the interpretation of the Qur'an, some Orientalists have been under the illusion of contradiction and have made contradictions about the Qur'an. One of them is Yusuf Haddad, who has attributed the existence of contradictions to the Qur'an, such as the creation of the earth and the sky, and the questioning or non-questioning on the Day of Judgment. In this article, while examining the doubts raised by him, he tries to state that the existence of any discrepancy and contradiction in the verses of the Holy Quran is nothing more than an illusion and the apparent contradiction that can be seen in the verses of the Holy Quran is removed with a little care and reflection.
Progressive Legal Perspective of the Settlement Child Criminal Action as a Narcotics User in the Malang City Police Resort
Authors: Trestiawan Ari , Sugiri Bambang , Djatmika Prija
Published: February 2022

The application of criminal conviction against children often causes debate. The philosophy of the juvenile justice system prioritizes the protection and rehabilitation of child perpetrators. Article 1 number 7 Indonesia Juvenile Criminal Justice System Law Number 12 of 2012 states the diversion is a diversion of the settlement of juvenile cases from the criminal justice process to the outside the criminal justice process. In the period 2017 to 2020, there were 12 suspected child users of narcotics crime at the Malang City Police Resort. Of the 12 cases of children as users of narcotics crimes handled by the Malang City Police Resort, none of which could be attempted by diversion. This means that all cases concerning children as perpetrators of narcotics crimes are all P21 or go to court. According to progressive law, cases of children should not be resolved in the mechanism stated in the existing formal text of the rules. The use of a progressive legal approach in solving cases of narcotics abuse by children is more effective because children are the future of the next generation of the nation's struggle and for the best interests of the children themselves.
The Implementation of Classroom Management in Teaching and Learning Activities
Authors: Sahib Abdul , Danim Sudarwan , Sahono Bambang , Somantri Manap
Published: February 2022

The general objective of this research is to describe the implementation of classroom management in teaching and learning activities at Madrasah Aliyah Negeri Rejang Lebong. Specifically, the purpose of this research is to discuss the teachers’ implementation of classroom management regarding (1) How the teacher maximizes the students’ freedom of expression during learning activities, (2) How the teacher develops the students’ expected behaviours and eliminate the unwanted ones. The research method used in this study is descriptive qualitative method. Observation, interviews and documentation were used as the technique for collecting the data. The research subjects were five people consisted of four teachers and one principal. The research results revealed two things in classroom management. (1) The cultivation of prayer before learning and learning culture is a meaningful experience to increase devotion and create or maintain an orderly class atmosphere; (2) The teacher can create a dynamic, optimal learning atmosphere and open interaction for the emergence of the students’ critical thinking.
Deception as a Condition for Cancellation of an Arbitration Award in Indonesia
Authors: Syahputra Tory Caesar , Budiono Abdul Rahmad , Sugiri Bambang
Published: February 2022

The phrase "deception" is one of the elements of the crime as a condition for the cancellation of an arbitration award, which is contained in the substance of Article 70 letter c of the Indonesia Arbitration and Alternative Dispute Resolution Law No. 30 of 1999. Elimination of explanation of Article 70 of Law No. 30 of 1999, the author sees that there is legal obscurity to the meaning of "deception" as a condition for the cancellation of an arbitration award. The norms as contained in Article 70 are the realm of criminal law, which in the settlement process is different from the realm of settlement through arbitration. This article is normative legal research with a statutory and conceptual approach. The result of this research is to explain and analyze the meaning of "deception" contained in the substance of Article 70 letter c of Law No. 30 of 1999 as a condition for the cancellation of an arbitration award. Whereas the element of "deception" which is used as a condition for the cancellation of an arbitration award in the arbitration settlement process is a criminal domain, so to prove this element must first be proven in the realm of criminal justice to obtain permanent legal force from the panel of judges. Elements of a criminal act cannot only be suspected but must be proven first.
Young People from "Technology" to Profession Training as a Factor of Competitive Personnel Training
Authors: M.Kh. Shomirzayev
Published: February 2022

The article describes the essence of the formation of professional qualities of students in the direction of school technology from the subject of school technology to the professions of national crafts through the ideas of oriental scholars on the work of vocational training of young people.
Gut Microbiota Modulates the Efficiency of Programmed Cell Death Protein 1 Cancer Immunotherapies
Authors: Samei Azam , Khedri Mostafa
Published: February 2022

Program cell death protein 1 (PD1) is considered as an inhibitory molecule that is expressed on the surface of activated T-cells and bound to PD-L1 and PD-L2 ligands. Several types of cancer cells express PD-L1 which can bind to PD1 on the surface of tumor-specific T-cells. PD1/PD-L1 ligation triggers a pathway to protect tumor cells from an effective response of tumor-specific T-cells. Different PD1/PD-L1 blocker antibodies are clinically used to promote the T-cell response against the cancer cells. Current studies suggest that the gut microbiome impacts the efficiency of PD1 blockade therapy in cancer patients. The association of several bacterial species with PD1 responder patients has been determined. The present study reviewed previous reports on the relation between the microbiome and immune checkpoint therapy (ICT). The results of studies were discussed considering adjuvant and molecular mimicry of microbial antigens by tumor-associated antigens and metabolic effects of microbial products on ICT.
Evaluating the MicroRNA Expression of IL-35 and IL-37 in Helicobacter pylori-infected Patients with Gastritis and Gastric Ulcer
Authors: Ahmadnia Zahra , Ranaee Mohammad , Mohammadi Abandansari Rouzbeh , Bagheri Nader , Shirzad Hedayatollah
Published: February 2022

Interleukin (IL)-35 and IL-37 are two anti-inflammatory cytokines. IL-35 inhibits the development of T-effector cells such as Th1, and Th17; while increasing regulatory T cells (Tregs). IL-37 causes the suppression of inflammatory cytokines. Regarding the positive impact of Helicobacter pylori (H. pylori) infection on inflammation and considering the anti-inflammatory effects of IL-35 and IL-37, this study aimed to evaluate the expression of these two cytokines in H. pylori-infected patients with gastrointestinal problems.
The case group consisted of H. pylori-infected individuals with gastric ulcer and/or gastritis (n=50) and the control group consisted of cases with gastric ulcer and/or gastritis non-H. pylori-infected (n=50). Sampling and classification of patients were based on pathology findings. A real-time polymerase chain reaction was performed for evaluating the IL-35 and IL-37 expression levels.
h.pylori-infected gastritis patients showed lower expression of IL-35 and IL-37 than the non-infected group. There was a significant difference between the expression levels of IL-35 and IL-37 in patients with gastric ulcers and/or gastritis who were infected and non-infected by H. pylori. There were no significant differences in the expression level of IL-35 and IL-37 in H. pylori-infected patients with gastric ulcer or gastritis.
Interleukins 37 and 35 were less expressed in patients with H. pylori-infection. In differentiation between patients with gastrointestinal symptoms who have H. pylori infection or with similar symptoms who do not have H. pylori-infection, mentioned interleukins can be used as diagnostic markers.
Identification of the Most Common Allergens of Acer velutinum Pollen
Authors: Sepahi Najmeh , Alyasin Soheila , Kanannejad Zahra , Esmaeilzadeh Hossein , Mohammadalizadeh Shirazi Farzaneh , Babaei Maryam , Farjadian Shirin
Published: February 2022

Pollens have been identified as potent inducers of allergic diseases worldwide. Acer velutinum (Persian maple) tree is an important source of allergic pollens in Iran. This study aimed to identify the immunoglobulin E (IgE)-reactive components of A. velutinum pollen extract in patients with maple allergy. We aimed to evaluate its allergenic components; using IgE in the serum of patients with maple allergy.
Twenty-two patients with a clinical history of reaction and a positive skin-prick test to maple pollen extract were included in this study. Identification of IgE-binding proteins in A. velutinum pollen extract was performed by immunoblotting using sera from sensitive patients.
A protein band with a molecular weight of around 70 kDa was the most IgE-reactive allergen in A. velutinum pollen extract detected by this method.
Identification of a protein with a molecular weight of about 70 kDa, as the most reactive allergen of A. velutinum pollen extract, can be considered as a potential allergen for designing diagnostic kits or as a target for immunotherapy of allergic patients with maple allergy.
Anaphylaxis in Cold Induced Urticaria: A Case Report and Review of the Literature
Authors: González-Díaz Sandra Nora , Fuentes-Lara Elma Isela , De Lira Quezada Cindy Elizabeth , Villarreal- González Rosalaura Virginia , Cruz-Cruz Rodrigo Alejandro de la
Published: February 2022

Cold-induced urticaria is considered as a subtype of physical urticaria and also the second most common type of chronic inducible urticaria. Contact with cold surfaces or the environment may cause systemic reactions, especially during aquatic activities. A 22-year-old female patient with a history of sulfa drug allergy began her condition 2 years before the presence of generalized pruritic erythema with hives as well as 2 episodes that had been characterized by facial angioedema and syncope 3-5 minutes after being in contact with cold air or surfaces.  On both events, she had just been outdoors on a cold, winter day. She was suspected to have cold-induced urticaria; thereby she had a positive reaction to the ice cube test. Due to the previous episodes of anaphylaxis, the patient was trained to administer intramuscular epinephrine. After 4 weeks of starting the treatment with antihistamines, no new events or injuries had occurred. Cold-induced urticaria may cause life-threatening reactions. The rate of anaphylaxis in these patients is low however, this case is presented to inform the importance of identifying this type of systemic reaction and preventing strategies.
Polymeric Nanoparticles in Cancer Chemotherapy: A Narrative Review
Authors: Yousefi Rizi Hossein Ali , Shin Dong Hoon , Yousefi Rizi Shima
Published: February 2022

Chemotherapy is a common treatment technique that uses chemical drugs to kill cancer cells. This technique affects normal healthy tissues being unspecific and has toxic adverse effects. Nowadays, nanotechnology applications in cancer chemotherapy have helped to solve the uncontrolled problems involving distribution of medicine particles and other side effects. Nanoparticles (NPs) can offer significant advantages over conventional drug delivery to have magnificent properties such as controlled mode of action, various methods of administration, and the ability to transport both organic/inorganic drug particles. Special ligands containing polymeric NPs preferentially hit the tumour site because of their chemical affinity to malignant tissues. This article, reviews the fabrication, characterization, and applications of NPs being used in chemotherapy. Furthermore, different forms of polymeric and especially polymeric chemotherapy were also explored and discussed to understand better the effects of NPs on cancer chemotherapy.