bluuebunny/crossref_metadata_2025 huggingface dataset:
The first review on prenatal drug exposure and ocular malformation occurrence
Authors: Dubucs Charlotte , Plaisancié Julie , Courtade-Saidi Monique , Damase-Michel Christine
Published: September 2024

Even though a non-negligible portion of congenital eye anomalies has a clear genetic origin, an etiology is not found for most patients. Prenatal medication exposure is recognized to be involved in fetal malformations and several medications are specifically known to alter eye morphogenesis during embryonic development leading to congenital eye defects. We explored and reviewed the role of medications described in the genesis of ocular malformations, a role that has been little evaluated and probably still underestimated especially since several studies have shown the wide exposure of pregnant women to medication. We present our results in two sections; the first describes medications reported to be associated with ocular malformations in humans; the second details medications responsible for ocular malformations in animal models. We have summarized these results in tables, providing a relevant tool for clinicians. As most of the associations between medication exposure and congenital eye defects are either old or single case reports, this study highlights the needs for high epidemiological vigilance, accurate clinical description as well as a combination of studies on human genetics and experimental studies. Since medication exposures are potentially modifiable risk factors for congenital anomalies, this represents an important opportunity to implement preventive measures.
Zinc: a potential star for regulating peritoneal fibrosis
Authors: Li Jian , Li Xinyang , Wang Yangwei , Meng Lingfei , Cui Wenpeng
Published: September 2024

Peritoneal dialysis (PD) is a commonly used renal replacement therapy for patients with end-stage renal disease (ESRD). During PD, the peritoneum (PM), a semi-permeable membrane, is exposed to nonbiocompatible PD solutions. Peritonitis can occur, leading to structural and functional PM disorders, resulting in peritoneal fibrosis and ultrafiltration failure, which are important reasons for patients with ESRD to discontinue PD. Increasing evidence suggests that oxidative stress (OS) plays a key role in the pathogenesis of peritoneal fibrosis. Furthermore, zinc deficiency is often present to a certain extent in patients undergoing PD. As an essential trace element, zinc is also an antioxidant, potentially playing an anti-OS role and slowing down peritoneal fibrosis progression. This study summarises and analyses recent research conducted by domestic and foreign scholars on the possible mechanisms through which zinc prevents peritoneal fibrosis.
The nutritional and feeding status of children living in selected residential child care facilities in Zambia: implications for programs and policies
Authors: Makhoul Zeina , Ndonji Mulemba , Long Julie M. , Moore Carolyn , Lunda Edgar , Mwandileya Watson , Taren Douglas
Published: September 2024

Introduction

This study aimed to estimate the prevalence of undernutrition and risk of feeding difficulties and describe common feeding practices for children from birth to 10 years of age living in residential care in Zambia.

Methods

This was a secondary analysis of de-identified cross-sectional data on 397 children living in 22 residential care facilities in four provinces. Child demographics, anthropometrics, hemoglobin levels, risk for feeding difficulties, and facility-level feeding practices were collected by a trained study team using Count Me In, a digital health app. Interviews with staff were conducted at 15 residential care facilities.

Results

Around half of the study sample were boys (53.4%) and <5 years old (55.4%). Special healthcare needs were reported in 10.3% of the children, with cerebral palsy being the most common (3.5%). Underweight, stunting, wasting (using weight-for-length/height), and anemia were found in 22.4, 28.0, 7.1 and 54.7% of children, respectively, with higher rates in children with special healthcare needs and children <24 months old. Duration of residential care was positively associated with length/height-for-age but not weight-for-age or weight-for-length/height z-scores. A risk for feeding difficulties was found in 41.4 and 26.0% of children with and without special healthcare needs, respectively. Suboptimal bottle-feeding practices, including the use of altered nipples and poor caregiver-infant interactions, were observed for infants <12 months old. Residential care staff reported suboptimal diets in their facilities and gaps in knowledge and resources to meet children’s nutritional needs.

Conclusion

These results demonstrate that a large proportion of children living in residential care in Zambia are at high risk for undernutrition and feeding difficulties and contribute to the small body of literature on children living in residential care, both in Zambia and globally. In the context of Zambia’s efforts to improve child nutrition and reform its alternative care, these findings can inform programming and policies for children living in residential care to fulfill their rights to health and family care.
A long time-series forecasting informer architecture-based ionospheric foF2 model in the low-latitude region
Authors: Qiao Feng , Xing Zan-Yang , Zhang Qing-He , Zhang Hong-Bo , Zhang Shun-Rong , Wang Yong , Ma Yu-Zhang , Zhang Duan , Lu Sheng , Varghese Manu
Published: September 2024

Deep learning models have made great accomplishments in space weather forecasting. The critical frequency of the ionospheric F2 layer (foF2) is a key ionospheric parameter, which can be understood and predicted by some advanced new deep learning technologies. In this paper, we utilized an Informer architecture model to predict foF2 for several hours up to 48 h and analyzed its variations during periods of quiet, moderate, and intense geomagnetic conditions. The Informer method forecasts the temporal variations of foF2 by processing and training the past and present foF2 data from the Haikou station, China, during 2006–2014. It is evident that the Informer–foF2 model achieves better prediction performance than the widely used long short-term memory model. The Informer–foF2 model captures the correlation features within the foF2 time series and better predicts the variations ranging for hours up to days during different geomagnetic activities.
The impacts of transaction costs and peer effects on pig farmers’ willingness to participate in a pig manure outsourcing treatment project
Authors: Zhou Kun , Wang Huan , Zhang Zhenwang , Li Jianqiang
Published: September 2024

This study aimed to explore the key factors affecting pig farmers’ willingness to participate in a pig manure outsourcing treatment project (PMOTP) from the perspectives of transaction costs and peer effects. Survey data from 512 pig farmers and the probit and Heckman probit models were used to estimate the impact of transaction costs and peer effects on farmers’ participation in the PMOTP. The results demonstrate that more than 62% of farmers are willing to participate in the PMOTP, and the average willingness to pay reaches 7.2 yuan/ton. Farmers’ willingness to participate in the PMOTP decreases with asset specificity, transaction frequency and uncertainty but increases with peer effects. Moreover, peer effects attenuate the inhibitory effect of transaction costs on farmers’ participation in the PMOTP. Heterogeneity analysis showed that large-scale farmers without the self-breeding and self-rearing model are more affected by transaction costs and peer effects than other farmers. Moreover, asset specificity and peer effects are likely to increase farmers’ willingness to pay for the project, which suggests that larger farms are more willing to invest in the PMOTP. These findings provide a useful reference for establishing a model for sustainable environmental service projects in the farming industry.
KONSEP AKHLAK DALAM KITAB TANBIHUL MUGHTARRIN KARYA IMAM AS-SYA’RONI DAN RELEVANSINYA DENGAN PENDIDIKAN
Authors: Yasin Hadi
Published: September 2024

Era modern merupakan era dimana marak sekali yang namanya perkembangan, baik itu perkembangan kebudayaan, perkembangan pendidikan maupun teknologi. Masyarakat Indonesia masih menjunjung tinggi tata krama dalam pergaulan sebagaimana anak bersikap kepada orang yang lebih tua maupun hubungan antar teman. Namun seiring laju perkembangan zaman dan perubahan cepat dalam teknologi informasi telah merubah sebagian besar masyarakat dunia terutama remaja. Untuk mendapatkan atau mencapai akhlak karimah yang sesuai dengan tuntunan agama, maka semua orang harus melalui sebuah proses yang dinamakan proses pendidikan akhlak. Konsep yang berkaitan dengan pendidikan akhlak dalam Islam terdapat dalam salah satu kitab yang berjudul kitab Tanbihul Mughtarrin. Bertitik tolak dari latar belakang di atas, penulis merumuskan masalah sebagai berikut: Bagaimana konsep akhlak dalam kitab Tanbihul Mughtarrin karya Imam Asy-Sya’roni? dan Bagaimana relevansi kitab Tanbihul Mughtarrin dengan pendidikan? Jenis penelitian yang penulis gunakan adalah library research (penelitian kepustakaan) yakni: Penelitian yang dilakukan mengumpulkan data dan informasi menggunakan kitab Tanbihul Mughtarrin karya Imam Asy-Sya’roni, terjemahan kitab Tanbihul Mughtarrin, buku akhlak (ciri manusia paripurna), dan juga jurnal serta karya-karya ilmiah dari tokoh lain yang terkait langsung dengan pembahasan dalam penelitian ini.  Analisis data dalam penelitian ini dilakukan dengan menggunakan analisis deskriptif, yaitu penelitian dengan langkah kerja untuk mendeskripsikan suatu objek, fenomena, latar sosial, dan sasaran penelian terjawablah dalam tulisan naratif. Artinya, data maupun fakta yang telah dikumpulkan oleh peneliti kualitatif berbentuk kata atau gambar. Setelah itu untuk mendapatkan kesimpulan penulis menggunakan pola penalaran induktif, yaitu pola pemikiran yang berangkat dari suatu pemikiran khusus kemudian ditarik generalisasi yang bersifat umum. Inti dari Konsep Akhlak Dalam Kitab Tanbihul Mughtarrin Karya Imam Asy-Sya’roni dan Relevansinya Dengan Pendidikan. Dalam kitab Tanbihul Mughtarrin mengandung suatu ajakan untuk mendekatkan diri kepada Allah SWT, mengulas etika-etika mulia para ulama salaf yang sholih, dengan mengutip maqolah-maqolah mereka dan juga mengutip sabda-sabda Nabi-Nabi terdahulu yang berkaitan dengan etika yang luhur. Dan dalam relevansinya dengan pendidikan akhlak itu segalanya dan posisi akhlak diatas pendidikan, bahkan Rasulullah SAW diutus untuk menyempurnakan akhlak.
Efeitos da terapia com lítio na função da glândula tireoide em pacientes adultos com Transtorno Bipolar: uma revisão integrativa
Authors: Moura Tayssa Figueiredo , Garcia Ana Clara Almeida , Machado Ester Alcântara , Silva Hevellyn Ribeiro , Barros Luana Vitória Lopes , Souza Júlia Beatriz da Fonseca , Pereira Thays Inocêncio , Alves Paulo Isaac Souza
Published: September 2024

O transtorno bipolar (TB) é uma condição de saúde mental caracterizada por mudanças extremas de humor, alternando entre episódios de mania, depressão, hipomania e normalidade. Diversos são os medicamentos utilizados para o seu tratamento, dentre eles o lítio, o qual apesar de ter eficácia no controle da mania, apresenta alguns inconvenientes relacionados ao sistema endócrino e renal. Objetiva-se elucidar de maneira concisa e através da literatura moderna, os efeitos acarretados pela terapia com lítio no TB à função da glândula tireoide. Para tanto, realizou-se uma revisão integrativa da literatura. A pergunta norteadora foi: “Qual é o impacto da terapia com lítio na função da glândula tireoide em pacientes adultos com transtorno bipolar?”. A busca da literatura foi realizada em maio de 2024 nas bases de dados PubMed e MEDLINE, utilizando-se os descritores “Bipolar Disorder”, “Thyroid” e “Lithium”, todos registrados no DecS/MESH. Foram considerados artigos que atendiam aos critérios de inclusão, publicados entre os anos de 2014 e 2024 em inglês e em português. Desse modo, foram incluídos doze artigos os quais abrangem alterações provocadas pelo tratamento com sais de lítio na glândula tireoide de pacientes com transtorno bipolar, o que permite concluir que o uso do lítio no tratamento do transtorno bipolar causa disfunções tireoidianas como hipotireoismo, bócio, hipertireoidismo e tireotoxicose.
Associação entre atividade física e prevenção de doenças cardiovasculares em pessoas vivendo com HIV: uma revisão sistemática com meta-análise
Authors: Christo Jéssyka Cristina Gomes de , Valenga Yasmin Pais , Jacobsen Indianara Pompermaier , Souza Luane Santana de Jesus , Martins Camila Marinelli , Muller Erildo Vicente
Published: September 2024

A infecção ocasionada pelo vírus da imunodeficiência humana (HIV), apesar dos avanços dos antirretrovirais, ainda representa um desafio para a saúde pública, visto que os indivíduos enfrentam riscos aumentados no desenvolvimento de doenças cardiovasculares. Analisar os efeitos da atividade física, seja aeróbica ou resistida, na saúde e prevenção de doenças do sistema cardiovascular (DCV) em pessoas que vivem com HIV. Realizou-se uma revisão sistemática após a obtenção de artigos em 7 bases de dados: PubMed, LILACS, IBECS, MEDLINE, Scopus, Web of Science, Scielo, com inclusão final de 28 artigos. A escala STROBE e a PEDro foram utilizadas para avaliar a qualidade metodológica dos estudos. A meta-análise foi realizada utilizando-se o pacote “meta” do Programa R Studio.  A análise dos artigos longitudinais incluídos revelou redução da glicemia quando o acompanhamento se deu entre 7 e 12 meses, com diferença significativa de -4,68 (IC 95%: -6,09; -3,27), redução do colesterol total após 6 meses de acompanhamento, com diferença de -4,52 (IC 95%: -7; -2,05), e aumento do HDL após 12 meses, com diferença de 2,8 (IC 95%: 2,05; 3,56). Nos estudos transversais a glicemia apresentou diferença significativa de -4,23 (IC 95%: -5,62; -2,83) e o IMC, -0,75 (IC 95%: -1,41; -0,10). Evidencia-se que a atividade física gera proteção para a saúde cardiovascular em indivíduos com HIV, reforçando a necessidade dos exercícios físicos como parte da terapêutica da população analisada.
Esperança verde: a cannabis no tratamento da Doença de Parkinson
Authors: Dias Larissa Emily Cardoso , Santos Paloma Nicole Souza dos , Arruda Isabela Tatiana Sales de
Published: September 2024

A Doença de Parkinson é caracterizada pela degeneração progressiva dos neurônios dopaminérgicos na substância negra do cérebro. Essa perda de dopamina, um neurotransmissor crucial para o controle motor, gera uma variedade de manifestações clínicas que podem ser divididas em sintomas motores e não motores. Entre os sintomas motores, destacam-se a bradicinesia, o tremor, a rigidez e a instabilidade postural. Já entre os sintomas não motores, incluem-se disfunções do sono, disfunções autonômicas, sintomas neuropsiquiátricos e alterações sensoriais. O presente estudo tem por objetivo entender a relação da Cannabis medicinal para o tratamento da doença de Parkinson, que demonstra auxiliar na neuroinflamação e neuroproteção, assim, proporcionando uma melhoria na qualidade de vida dos pacientes. Portanto, trata-se de uma revisão bibliográfica narrativa, na qual foram incluídos estudos transversais, com o intuito de abordar a importância promissora no tratamento da DP. Diante do exposto, é possível constatar a heterogeneidade dos estudos analisados e concluir que as evidências relacionadas ao tratamento da Doença de Parkinson com Cannabis medicinal ainda são limitadas, mas apresentam resultados promissores no alívio dos sintomas.
Avanços no diagnóstico e manejo da Asma Infantil: uma revisão atualizada das estratégias de tratamento e impacto na qualidade de vida
Authors: Gomes Mariana de Araújo , Gomes Anamaria de Araújo , Domingues Gabriela Palermo Correia , Maciel Larissa Diogo Viana , Dias Maria Fernanda Figueiredo Lanza
Published: September 2024

O artigo explora os avanços recentes no diagnóstico e tratamento da asma infantil, uma condição respiratória crônica que afeta milhões de crianças em todo o mundo. A asma é particularmente prevalente na população pediátrica, com cerca de 6 milhões de crianças afetadas nos Estados Unidos, das quais 4,2 milhões estão em idade escolar. Essa alta prevalência representa um desafio significativo para os sistemas de saúde, especialmente devido à falta de diretrizes padronizadas para o diagnóstico e tratamento em crianças. O diagnóstico de asma em pediatria é tradicionalmente baseado em parâmetros clínicos como tosse, dispnéia e chiado, mas a variabilidade na apresentação da doença dificulta a identificação precisa e precoce, resultando em subdiagnóstico e tratamento inadequado. Nos últimos anos, houve avanços importantes tanto no diagnóstico quanto no tratamento da asma infantil. Tecnologias inovadoras, como biomarcadores e técnicas avançadas de imagem, têm permitido uma identificação mais precisa dos subtipos de asma, possibilitando um diagnóstico mais acurado e individualizado. No que diz respeito ao tratamento, as diretrizes atuais enfatizam a importância de abordagens personalizadas, que consideram as características individuais de cada paciente, incluindo idade, gravidade dos sintomas e presença de comorbidades. A introdução de terapias biológicas, como o uso de anticorpos monoclonais, tem revolucionado o tratamento de casos graves de asma, melhorando o controle dos sintomas e reduzindo a frequência das exacerbações. Além dos avanços médicos, o artigo também discute o impacto da asma na qualidade de vida das crianças. As crises asmáticas não só afetam a saúde física, mas também têm implicações emocionais e sociais, como a limitação em atividades físicas e a possível exclusão social. A adesão ao tratamento continua sendo um desafio, e inovações tecnológicas, como dispositivos de monitoramento eletrônico, estão sendo desenvolvidas para melhorar a adesão medicamentosa.
Perspectivas atuais da Hanseníase na infância
Authors: Fernandes Tomaz , Reis Beatriz Modesto Prata , Montina Diego Neves , Gomes Jefferson Bezerra , Silva Yllana Ferreira Alves da
Published: September 2024

Introdução: A hanseníase é uma doença causada por microbactérias que afetam em especial nervos, mucosas e pele. Mesmo sendo uma doença muito antiga, a incidência de novos casos ainda é muito grande. Brasil se destaca como um dos países com maior quantidade de novos casos todo ano. Em regiões endêmicas com antígeno circulante, pode-se notar o aumento da incidência de casos de hanseníase em crianças, funcionando como um indicador de áreas mais afetadas. Objetivo: Analisar a hanseníase na infância. Metodologia: Trata-se de uma revisão integrativa na base de dados PUBMED utilizando os descritores “(PEDIATRIC OR CHILDHOOD) AND LEPROSY” para artigos publicados entre 2019 e 2024. Resultados: Ainda que a hanseníase tenha sido erradicada nacionalmente, alguns países como Cuba, China, Indonésia e Brasil apresentam regiões endêmicas específicas, geralmente com aumento de casos de hanseníase infantil. Um estudo de coorte prospectivo realizado no Brasil demonstrou que mesmo após o tratamento são comuns a manifestação de sintomas. A idade entre 8 e 14 anos, classificação multibacilar e mais de 10 lesões cutâneas ou formas virchownianas se relacionaram significativamente com desfechos mais graves da doença. O disgnóstico da doença é predominantemente clínico, mas técnicas laboratoriais tendem a indicar com sucesso o diagnóstico, principalmente na presença de manifestações raras. No que tange ao tratamento, as drogas e a posologia de escolha devem levar em conta a idade. Conclusão: O aumento da taxa de incidência de hanseníase em crianças pode servir como um poderoso indicador de regiões endêmicas da doença, onde a bactéria possa estar em constante circulação, visto que geralmente a transmissão ocorre por meio do contato e em indivíduos mais suscetíveis, no caso as crianças. Para auxílio do diagnóstico, é indicado o uso de exames como o esfregaço. A dose do tratamento varia de acordo com o tipo da doença, peso e idade da criança.
Estudo ecológico do perfil epidemiológico da toxoplasmose gestacional na Região Sul do Brasil
Authors: Castro Clara Oliveira , Torres Mariana Just Peixoto , Almicci Iasmin Vitória Sandri , Póvoa Maria Carolina Ramos , Pinto Jayana Teixeira Jales Menescal
Published: September 2024

Introdução: A toxoplasmose é uma infecção significativa no Brasil durante a gestação, com prevalência variando entre estados, chegando a 80% em algumas áreas. Dada a gravidade da doença congênita, é fundamental identificar casos agudos e gestantes propensas à infecção. Objetivo: Analisar o perfil epidemiológico da toxoplasmose gestacional na região Sul. Método: Estudo ecológico com dados do SINAN/DATASUS, considerando notificações por toxoplasmose gestacional no Sul de 2019 a 2023. Avaliou-se, por estatística descritiva, região e UF de notificação, idade gestacional, faixa etária, escolaridade, raça, evolução, classificação final e critério de confirmação por ano de notificação. Resultados: Neste período, foram registradas 10.714 notificações por toxoplasmose gestacional no Sul, representando 19,23% do país. Em 2019, houve 1.842 notificações e em 2023, 2.594. O Paraná liderou com 4.062 notificações. Genitoras de 20 a 39 anos representaram 77,7% dos casos. O 1º trimestre de gestação obteve maior número de notificações. Genitoras brancas foram maioria (74,6%). A escolaridade foi ignorada em grande parte (2.981). Dos casos, 80,4% foram confirmados e 10,7% descartados. A maioria das genitoras obteve cura (57,6%). O critério laboratorial foi usado em 89,8% dos casos. Conclusão: Notou-se um aumento das notificações pela doença no Sul ao longo dos anos, predominando em mulheres de 20 a 39 anos, com ensino médio completo e brancas. Destaca-se a importância de diagnósticos precoces e contínuos durante o pré-natal, especialmente no primeiro trimestre, e a necessidade de medidas preventivas, educativas e vigilância epidemiológica robusta.
Tratamento de Aneurisma de aorta abdominal: uma análise da literatura
Authors: Meirelles Cecília Marques , Resende Izabela Corrêa , Moreira Júlia Diniz Assis , Alencar Gabriela Simões , Gomes Maria Gabriela Gonzaga , Martins Maria Carmen Barbi , Mattos Clara Gomes Barbosa , Dias Pedro Soares , Lopes Stárley Augusto de Souza , Lima Mariah Pinheiro Rios
Published: September 2024

Introdução: Aneurisma é a dilatação permanente e focal de uma artéria, sendo o aneurisma da aorta abdominal (AAA) o mais comum. É diagnosticado quando o diâmetro do segmento afetado é de pelo menos três centímetros. A principal causa é a degeneração arterial por aterosclerose.  Os fatores de risco incluem idade avançada, sexo masculino, tabagismo e histórico familiar. AAA tem alta mortalidade se rompido. O tratamento inicial envolve controle dos fatores de risco e, se necessário procedimento cirúrgico, há o reparo endovascular (EVAR) e cirurgia convencional aberta. Este estudo visa caracterizar e comparar as principais modalidades de tratamento do aneurisma de aorta abdominal. Métodos: Esse estudo consiste em uma revisão integrativa das bases de dados Pubmed, Scielo e Lilacs referente aos anos de 2020 a 2024.  Utilizando os descritores: “Abdominal Aortic Aneurysm”, “Terapêutica” e “Procedimentos endovasculares”. Foram excluídos artigos publicados há mais de 10 anos, resumos e artigos com metodologias inconclusivas. Discussão: O tratamento é indicado para AAA sintomáticos e, em alguns casos, assintomáticos, baseando-se em critérios como taxas de crescimento e diâmetro. Na técnica aberta há duas possíveis abordagens: Transperitoneal e Retroperitoneal total, em ambas se realiza uma incisão longitudinal no saco do aneurisma para remover possíveis trombos e ateromas. A parede do saco é retirada, e um enxerto de poliéster ou politetrafluoretileno é suturado à aorta proximal. Já na EVAR envolve o acesso das artérias femorais e a inserção de enxertos de stent sobre fios-guia na aorta. Está relacionada à redução do tempo cirúrgico, redução de perda sanguínea, menor necessidade de transfusões sanguíneas e de ventilação mecânica. Conclusão: Em frente a uma doença com alta taxa de mortalidade como é o caso do aneurisma de aorta abdominal rompido, é necessário estudos e pesquisas para otimizar o diagnóstico e o tratamento. Sendo que o tratamento conservador é baseado na redução dos fatores de risco. Já os tratamentos cirúrgicos devem ser discutidos a melhor abordagem em cada caso, sendo que uma anatomia favorável junto com alto risco clínico contribui para a realização do procedimento endovascular. Ao passo que, uma anatomia desfavorável somada a um baixo risco clínico, será escolhida a correção aberta.
A eficácia da endoscopia no manejo de fístulas após cirurgias bariátricas
Authors: Silva Luísa Marques
Published: September 2024

Objetivo: Verificar a eficácia dos diversos procedimentos endoscópicos disponíveis a curto e longo prazo no tratamento das fístulas pós-bariátricas. Métodos: Trata-se de uma revisão integrativa realizada na base de dados MedLine com os descritores “Apneia Obstrutiva do Sono”, "Síndrome Metabólica", ''Tratamento” e suas variações no MeSH. Foram incluídos estudos originais em inglês, realizados com participantes maiores de 18 anos, publicados nos últimos 10 anos e excluídos aqueles cujos título e resumo não se enquadraram nos objetivos propostos. Resultados: Após a leitura e análise dos artigos, foram selecionados 6 para os resultados desta revisão. Os resultados foram agrupados baseando-se nos diferentes métodos endoscópicos existentes, avaliando suas respectivas eficácias, complicações e efetividade a longo prazo. Considerações finais: Embora existam diversas terapias endoscópicas distintas para o manejo das fístulas que surgem após as cirurgias bariátricas, não foi possível observar uma superioridade de nenhuma técnica perante às outras. Assim, faz-se necessário maiores estudos para acompanhamento a longo prazo.
Estudo comparativo do biomarcador procalcitonina entre pacientes internados e acometidos por Síndrome da Disfunção Respiratória Aguda (SDRA), Pneumonia associada à ventilação mecânica (PAV) e Síndrome respiratória aguda grave da Covid-19 (Sars- Cov-2)
Authors: Calzavara Neto Américo , Penso Catherine Damke , Esteves Gabriel El-Corab , Torres Ana Luiza Horta , Tiburcio Jacqueline Domingues
Published: September 2024

O objetivo desta pesquisa foi analisar a relação entre valores de procalcitonina, proteína C reativa (PCR) e escore SOFA (Sepsis-related Organ Failure Assessment) e a correlação destes indicadores com diferentes desfechos clínicos em pacientes internados em unidade de terapia intensiva geral e unidade de terapia intensiva dedicada a pacientes acometidos pela Covid 19, em um hospital de médio porte, em Minas Gerais. A relevância deste tema se deve ao atual uso indiscriminado de antimicrobianos e às escassas estratégias de manejo que contribuem para a resistência microbiana, bem como para a ocorrência de efeitos adversos. Assim, o uso de biomarcadores para orientar o tratamento com antimicrobianos pode promover a individualização do tratamento, evitando exposição antimicrobiana desnecessária e reduzindo as taxas de falha de tratamento.Neste estudo observacional tipo coorte, a amostra foi composta por adultos de ambos os sexos internados nas Unidades de Terapia Intensiva nas alas geral e COVID. Foram utilizados protocolos próprios do projeto de pesquisa com base nos critérios de inclusão e exclusão da amostra para determinar se será realizada a dosagem da procalcitonina e o protocolo próprio da instituição hospitalar para o tratamento antimicrobiano adequado ao paciente. Os prontuários serão utilizados para analisar o desfecho clínico, o tempo de internação, os exames realizados e os antibióticos utilizados. Este estudo demonstrou que o uso precoce de antibióticos em pacientes acometidos pelo Sars-Cov-2, com insuficiência respiratória, não impactou na mortalidade, quando comparado a pacientes com insuficiência respiratória e com níveis semelhantes de gravidade, internados na UTI Geral.
Ablação total bilateral do conduto auditivo em cão com otite crônica: relato de caso
Authors: Santos Maria Eduarda Cerqueira Alcantara dos , Cunha Magda Danyella Xavier Leite da , Brandão Tiago Oliveira
Published: September 2024

Total ear canal ablation (TECA) is recognized as the surgical procedure of choice for treating severe cases of chronic otitis in companion animals. When allopathic treatments or conservative protocols do not have the desired effect, otitis progresses and irreversible calcification of the ear cartilage occurs. The surgical method involves the complete removal of the ear canal, including the vertical and horizontal portions; the technique to be used is determined by the severity of the problem and the surgeon's decision. Considering the importance of TECA in clinical surgery, this case report documents the clinical presentation, surgical treatment and prognosis of a male mongrel dog, approximately five years old, affected by bilateral chronic otitis. Initially, the patient was treated clinically based on the history and symptoms presented, however, the response to medication was not completely effective. Given the chronic persistence of the disease, the animal underwent total ablation of both auditory canals, with the aim of correcting the clinical changes in order to provide a better quality of life and prevent future recurrences of otitis. The surgical technique used as treatment produced satisfactory results. Apart from deafness, there were no reports or observations of any postoperative complications such as infection or dehiscence of sutures.
First data on Culicoides (Diptera: Ceratopogonidae) from the Eastern Highlands of Algeria (Oum El Bouaghi): composition of the population and diversity
Authors: Belkharchouche Mounira , Aouadi Abdallah , Benchettouh Ahmed
Published: September 2024

Midges of the genus Culicoides Latreille 1809 are hematophagous dipterans known for their medical and veterinary importance. Some species are the principal vectors of various arboviruses such as heamorrhagic epizootic disease virus (EHDV), Schmallenberg virus (SBV) and Bluetongue virus (BTV). Thus, this study aims to highlight the composition of Culicoides fauna, and to describe the diversity of Culicoides species in the wilaya of Oum El Bouaghi (North-eastern Algeria). The entomological monitoring was carried out during four months from April to July 2013, using the UV light suctions traps (OVI type) placed on five mixed livestock farms in this region. Tapped specimens of Culicoides were identified morphologically to species level. In total, 943 specimens were caught belonging to 21 species of which 6 were undetermined. The most abundant species was C. newsteadi (53.97 %) across all collection stations which the abundance peaks was observed during the rainiest month (April) at Ain Babouche farm. The greatest population of Culicoides was collected at Bir Chehem farm (372 specimens) while the highest midge diversity was found at El Hassi farm (2.59). Meanwhile, the species richness was more important at the farms of Bir Chehem (17 species) and El Hassi (12 species), Berriche and Sigus farms hosted the most equitable communities (0.85). This study confirmed the presence of different Culicoides species particularly those implicated in the transmission of arboviruses, in Oum El Bouaghi and provided new insights into their diversity, which are necessary to implement appropriate control strategies of potential vector-borne diseases.
Discretization of Linearized Water Waves
Authors: Someze Mercy Nwansimdi , Uwamusi Stephen Ehidiamhen
Published: September 2024

The concept of linearized water wave theory is fundamental in fluid dynamics and extensively utilized for studying wave propagation in various aquatic environments. Water waves are crucial in many engineering and scientific fields like ocean and coastal engineering, ship hydrodynamics, and offshore engineering. However, the complexity of nonlinear wave dynamics has limited the accuracy of traditional numerical models, highlighting the need for a simpler yet robust approach. Linearized water wave theory offers a promising solution by assuming small-amplitude waves, which simplifies the governing equations and provides an efficient tool for wave analysis.

The numerical simulation of linearized water wave theory holds significant importance across a spectrum of engineering and scientific disciplines, spanning from coastal engineering to oceanography. This paper focuses on discretizing the Euler equation to facilitate precise and efficient numerical simulations of linearized water wave phenomena. The Euler equation, which governs the dynamics of inviscid fluid flow, undergoes linearization to simplify the mathematical formulation while preserving crucial wave dynamics. Discretization methods, including finite difference, finite element, or spectral techniques, are employed to approximate the continuous equations on a discrete computational grid. Subsequently, these discretized equations are numerically solved using iterative or time-stepping methods to forecast the evolution of water waves over time. The accuracy and stability of the numerical scheme are evaluated through convergence studies and validation against analytical solutions or experimental data.
Representation of local identity in Kaliningrad linguistic landscape
Authors:   Immanuel  Kant Baltic Federal University, Zubritskaya E. V. , Shkapenko T. M. ,   Immanuel Kant Baltic Federal University
Published: September 2024

The article is devoted to the analysis of linguoculturalelements presented in the linguistic landscape of Kaliningrad as markers of its residents’ localidentity. The basis of the geopolitical uniqueness of the Kaliningrad region is its emergence as a result of the Second World War on the lands of North-East Prussia, which until then had been a part of Germany. The absence of its own historical and cultural roots in the modern population of the region predetermines the peculiarities of local identity construction by means of applying to the elements of Prussian-German prehistory. The aim of the study is to identify the quantitative presence and qualitativecomposition of the names of commercial objects of Kaliningrad, containing locally labeled Prussian or German components. Taking into account the factor of permanent influence of onomasticon of the city on the linguocultural consciousness of the population, the paper attempts to establish the degree of familiarity of some locally marked units to the city residents. The quantitative analysis has revealed that ergonyms with a Prussian-German component constitute an insignificant part of the total number of commercial names. The use of some of them in a number of names multiplies the effect of the presence of post-German locality and forms a permanent visual background, within which the foreign historical past is acculturated and perceived as its own, culturally mastered present. The most frequent markers of German locality in ergonymic nominations include the former name of theregion and the city (Königsberg, Prussia), as well as the surname of the philosopher Immanuel Kant. The graphical form of locally marked ergonyms varies from the spelling typical ofGerman or Russian to different variants of combined graphics. The survey of Kaliningrad respondents has revealed that the names of commercial establishments, which include the astyonym Königsberg and the choronym Prussia in their composition, are among the well-known ones, while the names based on the use of German hodonyms, agoronyms and anthroponyms are not among the number of significant elements of the linguistic landscape forming the local identity of the residents.
A Study Of Creep And Shrinkage In Concrete With A Consideration Of Its Effects On Curved Post-tensioned Concrete Bridges
Authors:   ,   Cork Institute of Technology, O'Sullivan William
Published: September 2024

"The first objective of the project was to explore the differences between Ordinary Portland Cement (OPC) and Ground Granulated Blast-Furnace Slag (GGBS) cement. The use of GGBS cement concrete is increasing in industry due to the environmental and durability benefits it gives compared with OPC concrete. Data on the creep properties of GGBS cement concrete is limited compared with the data that is available for OPC concrete. Laboratory testing was undertaken to determine the different effects of creep on OPC concrete and GGBS concrete. The second project objective was to research the effects of creep on post - tensioned curved concrete bridges. This type of bridge construction is widely used in modern times. The effect of creep on such structures is generally well detailed in design codes when the structures are of uniform construction and geometry. However, little guidance is available on the effects of creep on post-tensioned concrete bridges with horizontal curvature. This topic was explored in detail. A comprehensive literature review was undertaken. Relevant literature was studied to gain a comprehensive knowledge of creep and shrinkage in concrete. Literature was studied pertaining to the effects of creep on structural systems and different types of curved post - tensioned concrete bridge construction. The report outlines a schedule of laboratory tests that were devised and implemented to study the effects of creep on different concrete samples with varying GGBS cement content. The tests involved four reinforced concrete cantilever beams subjected to two point loads. Three of the beams had varying amounts (25%, 50% and 70%) of GGBS mixed with OPC. The results from the laboratory were collated with the results from hand calculations and a transient finite element analysis. Following on from the laboratory testing, the report describes the theory that the finite element software uses to analyse concrete creep. Finite element analyses of single-span and three-span curved post-tensioned concrete bridges were undertaken. The results of the analysis were collated. A number of conclusions and recommendations are detailed."
What Is The Effectiveness Of Public Relations Tactics Being Utilized By High Street Fashion Brands To Encourage Consumer Knowledge Of Their Brand Identity?
Authors:   ,   Cork Institute of Technology, Ferrari Lynn
Published: September 2024

"This thesis looks to discover if high street fashion brands are utilizing effective public relations. It attempts to identify if the PR tools being utilized by high street fashion brands are evident to the consumer and if they contribute to purchasing power, the model of communication that is being employed by high street fashion brands and if age contributes to the knowledge and effectiveness of public relation tactics and communication tools. Approach: The research involved a two-stage study with the first phase focusing on an extensive literature review of the key sources of secondary research including reports, articles and publications. The second stage of the study was conducted through qualitative research, which involved a set of interviews and focus groups. A semi structured interview was utilized in order to discover an insight into the thoughts and opinions of professionals working in the fashion industry from a PR, journalistic and fashion brands point of view. The interviews were supported with two focus groups where pailicpants were selected based on their age and if they are active consumers in the high street fashion industry. Results: The results indicate that high street fashion brands that utilize effective public relations have a stronger brand identity in the opinion of the high street fashion consumer. Online PR is a powerful tool for communicating with a brands publics. If a brand has no online presence it falls behind its competitors in the high street fashion industry and is viewed as old fashioned according to resuls in this study. This study demonstrates that effective PR tactics can have a positive effect on consumer opinions of a high street fashion brand. Findings conclude that social media facilitate two-way communication and show that social media is a necessary tool when communicating with a new generation of consumers in their 20’s and 30’s. In analyzing these findings the researcher found that age did have an effect on the knowledge of public relations tactics and also the effectiveness of the tactics on particular consumer target markets."
The main threats and risks for landscaping in Moscow in 2022 from dendrophilic invaders
Authors: Гниненко Ю.И.
Published: September 2024

Дендрофильные инвайдеры стали одной из важных проблем в озеленении Москвы и Подмосковья. В 2020-2021 гг. развитие погодных условий привело к тому, что некоторые из инвайдеров смогли существенно увеличить численность и нанесли сильные повреждения, тогда как численность других заметно снизилась.

Dendrophilic invaders have become one of the most important problems in the landscaping of Moscow and the Moscow region. In 2020-2021 the development of weather conditions led to the fact that some of the invaders were able to significantly increase the number and caused severe damage, while the number of others decreased markedly.
PERSPEKTIF HUKUM ISLAM TERHADAP SISTEM PANJAR BURUH TANI (STUDI KASUS DESA SUGIHWARAS KECAMATAN WONOMULYO)
Authors: Karmila Karmila , Busrah Busrah , Hindi M Anwar
Published: September 2024

Penelitian ini bertujuan untuk mencapai dua hal: pertama, ingin mengetahui bagaimana buruh tani di Desa  Sugihwaras, Kecamatan Wonomulyo menerima uang muka. 2) Untuk mengetahui apakah sistem uang muka buruh tani di Desa  Sugihwaras, Kecamatan Wonomulyo tunduk pada tinjauan hukum Islam. Penelitian kualitatif digunakan dalam penelitian ini. Sumber data yang digunakan adalah data primer dan data sekunder. Teknik pengumpulan informasi yang digunakan adalah strategi pengamatan, wawancara, dan dokumentasi. Upah yang diterima buruh adalah Rp. 1.200.000/hektar. Buruh yang membutuhkan uang panjar harus ikut bekerja terlebih dahulu selama 2 atau 3 hari, kemudian upah yang bisa di dapat dari hasil kerja tersebut akan diberikan. Sistem pembayaran panjar tersebut sudah sesuai dengan hukum Islam, karena sudah jelas mengenai besaran upah dan waktu pembayarannya serta besaran uang panjar yang diberikan kepada buruh, sehingga tidak ada yang merasa dirugikan dalam akad tersebut.
Parental Knowledge on Prevention of Early Childhood Caries and the Effectiveness of a Leaflet Intervention
Authors: Elkarmi Rawan , AlJafari Ahmad , Haddad Sarah , Al Soud Dina
Published: September 2024

Background: Parental education on child oral health plays an important role in caries prevention. Leaflets are a means of delivering educational messages. This study aims to evaluate the efficacy of leaflets in improving parental knowledge on prevention of early childhood caries.
 
Methods: This was a cross-sectional study. Parents of children younger than six years attending a pediatric clinic at a large hospital were asked to complete a questionnaire that noted their sociodemographic characteristics, oral hygiene practices, and knowledge on prevention of early childhood caries, which was given a score out of 20. After reading an educational leaflet, a follow-up phone interview was conducted to evaluate any improvement in parental knowledge. ANOVA and McNemar’s tests were used for statistical analysis.
 
Results: Three hundred and ninety-one parents participated in the study. The average knowledge score pre-intervention was 6.4 out of 20. Approximately 10% of parents were regular dental attenders. Around 12% of parents were aware of the correct age of the child’s first dental visit and the correct age to start tooth brushing; 20.5% knew about fluoride varnish; 7.2% understood that sugar-containing snacks should be consumed all at once; and, less than 50% believed that regular dental visits prevent caries. After reading the leaflet, there was a statistically significant improvement in almost all variables evaluating parents’ knowledge on prevention of early childhood caries.
 
Conclusion: Knowledge on prevention of early childhood caries among this sample of parents was very poor. Leaflets were successful in improving parental knowledge. There is a need to distribute such leaflets in healthcare centers and hospitals and to evaluate their efficacy further by comparison with other means.
Comparison of the Work Process Methods for Scale Invariant Feature Transform and Sum of Squared Difference in Image Mosaic
Authors: Widodo Anteng , Ikhwan Syariful , Santiko Irfan
Published: September 2024

Mosaic image is an image made from a collection of many other small images placed side by side, so that from a distance it looks like one big image. The use of this mosaic image varies, for example in digital image processing, in the context of image analysis, mosaic can also mean the process of combining several images with overlap to create one large image, for example in geographic mapping using satellite imagery. Then as a pattern creation in the field of design, mosaic images are used to create complex or abstract patterns, which can be used in decoration, architecture, or product design. Mosaic image is a combination of several images to get a wider view. One of the problems in mosaic image is in the image matching process, the right image matching can produce a better mosaic image. This study will compare the image matching method with RANSAC and SSD. The mosaic image of both methods was tested using objective fidelity criteria. The results showed the RANSAC method with an MSE value of 121.5820 and a PSNR value of 27.2821 dB, while the SSD method with an MSE value of 140.8373 and a PSNR value of 26.6436 db. The RANSAC algorithm is good for use in cases of mosaic images with feature-based methods, while SSD is good for use in cases of mosaic images with direct methods.
Strategi Pengembangan Pada Pabrik Roti Sedap Jaya Di Kelurahan Tingkulu Kecamatan Wanea Kota ManadoStrategi Pengembangan Pada Pabrik Roti Sedap Jaya Di Kelurahan Tingkulu Kecamatan Wanea Kota Manado
Authors: Paratan Yersin , Baroleh Jenny , Porajouw Oktavianus
Published: September 2024

This study aims to determine the marketing strategy of existing bread at the Sedap Jaya Bakery Factory. This research was conducted for three months, from April to May 2023. The sampling method was purposive sampling. The data used are primary and secondary. The analytical method used is SWOT analysis.The results showed that based on the SWOT analysis, the results showed that the marketing strategy for Sedap Jaya bread was in quadrant 1, namely taking advantage of strengths and opportunities as well as minimizing weaknesses and preventing threats
Analysis of Networking Tools Using Cisco Packet Tracer (CPT)
Authors: Thoyyibah. T  , Hidayat Asep Ridwan , Hanggara Imam Satria , Sudarsono Rizki Satriawan
Published: September 2024

This study aims to evaluate the performance and effectiveness of network devices using Cisco Packet Tracer (CPT) as a simulation tool. CPT is a widely utilized network simulation software, commonly employed for designing and testing network configurations prior to real-world implementation. This research investigates various network topologies to assess the performance of devices such as routers, switches, and end devices. The research methodology encompasses the design of network scenarios, device configuration, and testing of various network protocols. The analysis reveals that CPT is capable of accurately replicating most functions and behaviors of network devices, providing a clear depiction of network performance under different conditions. The findings suggest that CPT serves as an effective and efficient tool for both educational purposes and network planning, despite certain limitations in features and realism when compared to actual hardware. This study is expected to offer valuable insights for professionals and academics in understanding and optimizing network design before deployment in real-world environments.