bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of single-cell landscapes among three amniotes reveals conservation and innovation in avian immune systems
Authors: Fang Lingzhao , Wang Fei , Ren Jilong , Zhou Yaqi , Huo Wuqiang , Liu Huichao , Qin Mumu , Jing Yi , Yin Zhong-Tao , Shi Tao , Shan Huiquan , Tan Guanghui , Wang Haoping , Guo Xi , Mei Junpu , Yue Zhen , Hou Zhuo-Cheng , Zhou Huaijun , Song Jiuzhou , Degn Søren , Lin Lin , Luo Yonglun , Meng Feilong , Fang Xiaodong , Zhang Haihan , He Xi , Jiang Yu
Published: November 2024

Molecular characterization of chicken cells is essential for understanding avian physiology and vertebrate evolution, yet an organism-wide single-cell atlas in chicken is still lacking. Here we describe a comprehensive reference atlas of the chicken, encompassing 1.57 million cells across 149 cell types, along with a spatial transcriptomic map of the embryo. By integrating it with 1.2 million single cells from humans and turtles, we systematically explored the evolutionary rates of various cell types, particularly immune cells. The rapid evolution of chicken cells was generally characterized by changes in their gene regulatory networks and subsequent functional adaptations. In chicken, follicular dendritic cells emerge at the early development stage and exhibit myeloid rather than stromal origins, unlike in mammals. These cells share a regulatory network with mononuclear phagocytes and promote B cell proliferation and migration in the chicken-specific bursa of Fabricius. The observed variation in subtypes and proportions of γδ T cells across the three species reflected the evolution of pathogen recognition and signaling mechanisms among amniotes. Overall, our study provides an invaluable resource to study chicken cell biology and avian evolution and shines light on the evolutionary and cellular characteristics of immune cells across amniotes.
From National Identity to Well-being: The Crucial Mediating Role of Self-esteem in Adolescents
Authors: Yang Yue , Zhan Jun , Fan Yanwen
Published: November 2024

This study aims to explore the relationships between national identity, self-esteem, and subjective well-being among adolescents, with a particular focus on the mediating role of self-esteem between national identity and subjective well-being. A questionnaire survey conducted among 1,948 Chinese adolescents revealed significant positive correlations between national identity, self-esteem, and subjective well-being (p < 0.01). Gender, status, and place of birth significantly influenced national identity, self-esteem, and subjective well-being (p < 0.05). Structural equation modeling analysis revealed that national identity has a positive and direct effect on self-esteem (estimate: 0.48, SE = 0.03, p < 0.001); self-esteem has a positive and direct effect on subjective well-being (estimate: 0.59, SE = 0.03, p < 0.001); and national identity has a positive and direct effect on subjective well-being (estimate: 0.25, SE = 0.05, p < 0.001). Additionally, self-esteem plays a crucial mediating role between national identity and subjective well-being (p < 0.001). These findings underscore the importance of national identity in adolescents’ mental health and well-being and highlight the key role of self-esteem in moderating this relationship.
CEACAM1 Orchestrates Lipid Raft Dynamics and B-cell Receptor Signaling in Mantle Cell Lymphoma
Authors: Ngo Vu , Xavier Serene , Khairnar Vishal , Nguyen Vivian , Phan An , Yang Lu , Nelson Michael , Wang Jinhui , Li Aimin , Geng Huimin , Lee Jaewoong , Sadras Teresa , Pham Lan , Wiesenberger Dennis , Chan Wing , Lang Karl , Shouse Geoffrey , Danilov Alexey , Song Joo , Müschen Markus
Published: November 2024

B-cell receptor (BCR) signaling plays an important role in the pathogenesis of mantle cell lymphoma (MCL), but the detailed mechanisms are not fully understood. In this study, through a genome-wide loss-of-function screen, we have identified carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) as an essential factor in a subset of MCL tumors. Our BCR signal transduction studies revealed that CEACAM1 plays a critical role in BCR signaling by orchestrating two dynamic processes. First, following BCR engagement, CEACAM1 stabilizes membrane microdomains (lipid rafts) by anchoring to the F-actin cytoskeleton through adaptor protein filamin A. Second, CEACAM1 recruits and increases the abundance of SYK in the BCR complex leading to BCR activation. These activities of CEACAM1 require its cytoplasmic tail and the N-terminal ectodomain. Considering that previous studies have extensively characterized CEACAM1 as an ITIM-bearing inhibitory receptor, our findings regarding its activating role are both surprising and context-dependent, which may have implications for BCR-targeting therapies. Main Text:
HR Analytics for Strategic Decisions: Resolving Conflicts from a Psychological Perspective
Authors: Alam Md. Shaniul
Published: November 2024

This paper explores the role of HR analytics in decision-making. HR analytics involves the use of data to enhance human resource functions. It helps organizations make informed choices. This approach is essential for improving workforce management. It supports leaders in understanding employee behavior and performance. EI enhances interpersonal relationships in the workplace. This allows leaders to manage emotions effectively. This is important for resolving conflicts. Leadership psychology also helps leaders understand team dynamics. This understanding improves conflict resolution strategies. We examined how EI and leadership psychology can enhance HR analytics. We utilized structural equation modelling (SEM) through SmartPLS 4. This method allowed us to analyse complex relationships. This approach provided clear insights into how these elements interact. Our findings show that HR analytics can identify potential conflicts early. It can also offer solutions on the basis of data-driven insights. Emotional intelligence supports conflict resolution by fostering collaboration. Leaders with high EI can create a positive work environment. This leads to better team cohesion and productivity. The insights gained from this study contribute to organizational effectiveness. They highlight the importance of employee satisfaction. Engaged employees are more productive and less likely to leave the organization. By integrating HR analytics with EI and leadership psychology, organizations can enhance decision-making. This leads to proactive conflict management and improved workforce dynamics. Additionally, the integration of these elements is vital. This helps organizations manage challenges effectively. It also fosters a culture of understanding and collaboration. These strategies ultimately contribute to the success of the organization.
Hochschulpolitische Partizipation Studierender im Kontext nachhaltiger Hochschulentwicklung in Deutschland
Authors: Steger Aline
Published: November 2024

Studentische Partizipation ist zentral für die Hochschulentwicklung und bildet gleichzeitig die Grundlage für eine Bildung für nachhaltige Entwicklung (BNE). Die theoretische Auseinandersetzung mit verschiedenen Begriffen und Modellen von Mitbestimmung und Partizipation zeigt eine Bandbreite von formaler Beteiligung bis hin zur Teilhabe an Entscheidungsprozessen. Praxisbeispiele aus dem Bereich der nachhaltigen Hochschulentwicklung verdeutlichen, wie studentische Partizipation im Sinne echter Mitbestimmung gestaltet werden kann. Dieser forschungsgeleitete Entwicklungsbeitrag thematisiert Herausforderungen und Chancen in der Hochschulpraxis in Bezug auf hochschulpolitische Partizipation und betont die Notwendigkeit, studentische Partizipation als integralen Bestandteil nachhaltiger Hochschulentwicklung zu fördern.
Schein-Partizipation überwinden – Entwurf eines Partizipationsmodells für Fachschaften
Authors: Biehl Annalisa
Published: November 2024

Die bislang vorliegenden Studien zur Partizipation von Studierenden verweisen auf ein abnehmendes hochschulpolitisches Engagement, unter anderem in Bezug auf die Beteiligung in Fachschaften. Noch kaum untersucht ist dabei bislang, welche institutionellen bzw. organisatorischen Faktoren seitens der Hochschule die geringe Partizipation(-sbereitschaft) erklären können. Angesichts dessen sollen in diesem Beitrag zunächst potenzielle Hürden in Bezug auf die Arbeit von Fachschaften herausgearbeitet werden, um in einem weiteren Schritt in Anlehnung an die Empfehlungen des Wissenschaftsrats sowie den Students-as-Partners-Ansatz ein anzustrebendes Partizipationsmodell für Fachschaften zu entwerfen.
Prozessbegleitung studentischer Partizipation in Hochschullehre und Curriculumsentwicklung
Authors: Leben Nora , Reinecke Katja , Heiner Cynthia E.
Published: November 2024

Werden Studierende mit ihren Erfahrungen aktiv in die Hochschullehre und Curriculumsentwicklung eingebunden, verändern sich Gestaltungsräume für die Konzeption und Umsetzung lernförderlicher Studienangebote. Der Artikel beschreibt die Prozessbegleitung, Mitgestaltung und Unterstützung für die erfolgreiche Zusammenarbeit in Partnerschaften zwischen Studierenden und Lehrenden auf Kurs- und Curriculumsebene. Auf der Grundlage von Befunden aus zwei partizipativen Projekten (Students as Partners, Students’ University) an der Freien Universität Berlin werden übergreifende Prinzipien und Gelingensfaktoren identifiziert, die eine effektive studentische Teilhabe ermöglichen.
Individuelle Lernprozesse begleiten – wie geht das? Ko-Kreation in der Lehrentwicklung mit Design Thinking
Authors: Hatsikas-Schroeder Nina , Rüdisühli Tanja , Amstutz Jeremias , Zimmermann Jacqueline
Published: November 2024

„Individuelle Lernprozesse begleiten – wie geht das?“  Diese Frage wurde mit der Methodologie Design Thinking an der Fachhochschule Nordwestschweiz (FHNW) in einem zweijährigen Lehrentwicklungsprojekt bearbeitet. Verortet im Bachelor Soziale Arbeit der Hochschule für Soziale Arbeit FHNW, wurde das Projekt in Kooperation mit Akteur:innen des BA Data Science der Hochschule für Technik FHNW und BA Prozessgestaltung der Hochschule für Gestaltung und Kunst FHNW umgesetzt. Das ko-kreative Projektdesign erschloss und bündelte die vorhandene Erfahrung und Expertise von Studierenden und Lehrenden im Kontext der Begleitung individueller Lernprozesse und führte diese konzeptionell zusammen. Anschlussfähige Vorschläge für die Implementierung der Erkenntnisse in Bildungsformaten der Fachhochschule sind entstanden.
Studentische Partizipation in einem agilen Lehr-/Lernkontext
Authors: Wittich Christiane
Published: November 2024

Der Beitrag beschreibt die Gestaltung studentischer Partizipation im Projekt „Agiles Lernen im Fernstudium“ eines Mastermoduls der Bildungswissenschaft an einer Fernuniversität. Agilität wird hier als Schlüssel zu neuem Lernen betrachtet, das im Gegensatz zu reproduktiven, lehrerzentrierten Methoden einen flexiblen, selbstgesteuerten und studierendenzentrierten Ansatz verfolgt. Lernprozesse erfolgen iterativ, werden gemeinsam hinterfragt und Entscheidungen kollaborativ getroffen, was eine hohe Anpassungsfähigkeit und zukunftsrelevante Kompetenzen fördert. Durch soziale Interaktionen wird die Verantwortungsbereitschaft der Lernenden gestärkt und eine gemeinsame Lehr-/Lernkultur entwickelt.
Studierende in hochschuldidaktischen Weiterbildungskursen beteiligen – ein erfahrungsbasierter Vorschlag
Authors: Gysin Stefan , Schirlo Christian , Tremp Peter
Published: November 2024

Der Beitrag präsentiert ein Konzept eines hochschuldidaktischen Weiterbildungskurses für Mediziner:innen und Gesundheitswissenschaftler:innen, welches die studentische Perspektive systematisch integriert, indem Studierende sich an diesen Veranstaltungen beteiligen und ihre Sicht auf Lehre, ihre Erfahrungen im Studium und ihre Vorstellungen gelingenden Lernens einbringen. Diese studentische Perspektive trifft in diesen Kursen einerseits auf Sichtweisen und Einschätzungen von Dozierenden und ihre spezifischen beruflichen Erfahrungen und Herausforderungen in der Verknüpfung von Lehre, Forschung und Klinik sowie andererseits auf Erkenntnisse aus der Hochschuldidaktik. Die Kurse beabsichtigen eine Erweiterung und Differenzierung hochschuldidaktischer Kompetenzen von Dozierenden, angestrebt ist Lehr­entwicklung und Lehrqualität in diskursivem Austausch mit studentischer Beteiligung.
The Process of Academic Success Among Black Women: A Retrospective Constructivist Grounded Theory Study
Authors: Jeter Sandra
Published: November 2024

Black girls and women are regarded as one of the most vulnerable populations of students in academic settings. The research that highlights their academic experiences is generally deficit-based and does not emphasize models of success. The recognition of their educational accomplishments is often lacking in the body of knowledge and scholarly literature. Instead, a continued focus on their stigmatized group connection and at-risk status are present in research discourse. This retrospective grounded theory study aimed to move the current discourse to a strengths-based perspective focused on academic success. Intensive interviews were conducted to examine the academic experiences of twelve Black women. The emerged theoretical model posits that persistence leads to academic success and is facilitated by parental, psychosocial, and interpersonal factors. The model may guide those interested in supporting the academic retention and success of Black girls and women.
“Safe spaces are built": How African American Women Discuss Professional Connectedness in Online Doctoral Programs
Authors: Payne Rhemma , Harrison Ariel , Griffin Maranda
Published: November 2024

African American women represent steadily increasing enrollments each year in online doctoral programs. Despite their growing presence in academia, limited research exists to understand the experiences of African American women enrolled in online degree programs, including the barriers to success, and the supportive interventions necessary to help African American women see their educational endeavors to fruition. This paper explores the results of a qualitative research study focused on the conversations that arose in a sister circle style focus group to understand connectedness and the use of safe spaces to foster meaningful relationships that can be linked to African American women’s perception of belonging in online degree programs. Using constructivist grounded theory techniques from a Black feminist thought theoretical framework, the authors conducted semi-structured interviews and observations across two focus group sessions with four African American women attending online doctoral programs. The data was analyzed using the constant comparative method (CCM) and results illuminated themes of authenticity and safety, with sub themes that described features of a safe space which included intentional, genuine, and supportive.
Promotion of African American Women Scholars After Tenure
Authors: Young Jemimah
Published: November 2024

This editorial discusses the systemic challenges African American women scholars face in academia, particularly post-tenure. Despite their significant contributions, these scholars remain underrepresented in senior academic leadership due to intersecting racial and gender biases. The editorial highlights barriers such as implicit bias, disproportionate service responsibilities, and limited mentorship opportunities that impede their advancement. It advocates for institutional reforms, including transparent promotion criteria, equitable mentorship, and fostering inclusive academic cultures, to support African American women scholars beyond tenure and promote diversity in academic leadership.
Radical pericardiectomy for the treatment of constrictive pericarditis: Single-center experience in Vietnam
Authors: Thuan Phan Quang , Han Tran Quoc , Thang Ho Duc , Dinh Nguyen Hoang
Published: November 2024

Background: Constrictive pericarditis (CP) is a chronic inflammatory condition often necessitating surgical intervention. Radical pericardiectomy is the standard treatment, but the use of cardiopulmonary bypass (CPB) varies based on intraoperative hemodynamics. This study aims to evaluate the effectiveness of radical pericardiectomy combined with CPB and the apical suction device in treating CP.
Methods: We conducted a single-center retrospective analysis of 10 patients undergoing radical pericardiectomy for CP. Clinical data, surgical details, and postoperative outcomes were collected. Follow-up assessments included echocardiographic and clinical evaluations at 3 months, with a mean survival follow-up duration of 30.9 ± 21.3 months.
Results: Among the included patients, 60% underwent CPB during surgery. Despite longer recovery times and hospital stays, CPB usage did not increase postoperative complications. Echocardiographic and clinical assessments at 3-month follow-up revealed significant improvements in cardiac function and symptom relief. No cases of CP recurrence were observed during the follow-up period.
Conclusion: Radical pericardiectomy combined with CPB and the apical suction device demonstrates effectiveness in treating CP, with favorable short-term outcomes and low recurrence rates. Further studies with larger sample sizes and longer follow-up durations are warranted to validate these findings.
SEMANTIС FEATURES OF LEGAL TERMS IN ARBITRATION DISCOURSE (THE CASE OF ENGLISH LANGUAGE)
Authors:   St. Petersburg State University, Abishov Kanan E. , Abramova Eugenia V. ,   St. Petersburg State University
Published: November 2024

The study is a semantic analysis of the frequency of use of English legal terms, identification of possible changes in the meaning and interpretation of key concepts of English legal terminology on the material of ICC (International Chamber of Commerce), LCIA (London Court of International Arbitration) and ICSID (International Centre for Settlement of Investment Disputes) documents. The purpose of this study is to identify and analyze the general trends and standards of arbitration language. The subject of the study is the evolution of legal vocabulary in international arbitration, the object is the use of legal terms in arbitration practice. In the conditions of constant changes in the international arbitration sphere, the relevance of this study is undeniable. The results reveal the frequency of use of some archaisms and common words in legal contexts, the main findings emphasize the importance of adapting terminology to different cultural and legal contexts, and provide valuable perspectives for practitioners of international arbitration.
CANCEL CULTURE IN THE INTERNET LANGUAGE: VERBAL AND NON-VERBAL MEANS
Authors:   St. Petersburg State University, Zagorodnyaya Elizaveta L.
Published: November 2024

Today, the “cancellation culture” is becoming increasingly popular. This phenomenon is the process of publicly condemning actions, words and ideas that are considered unacceptable or offensive to certain social groups. The statements and actions of public figures often become the most discussed topics in online communities. The aim of this paper is to investigate the concept of ‘cancellation culture’ and its reflection in the language of the Internet. In this study, methods such as observation, analytic-synthetic analysis, content analysis, case method, lexico-grammatical and stylistic analysis have been used. The importance of this work is to identify the means of realising the concept of “cancellation culture” in social networks. The results of the work will be materials that can be used as cases for analysis by media specialists, as well as in the sphere of education in fields such as linguistics, journalism and PR.
FUNCTIONING PECULARITIES OF NICKNAMES IN MODERN NEWS MEDIA
Authors:   St. Petersburg State University, Kobtseva Anna Y. , Akay Oksana M. ,   St. Petersburg State University
Published: November 2024

The article considers the main characteristics of modern media texts. The aim of the study is to analyse the features of modern media texts and the manifestation of such a linguistic phenomenon as nicknames. The main models of formation and use of nicknames were identified on the material of news telegram channels with the number of subscribers above 10 thousand and American news media. Modern media have assumed the function of the main broadcasting resource, often not only a neutral broadcaster, but also a commentator. One of the vivid language phenomena to realise this function has been the use of nicknames. As the result of the research, it was found out that nicknames can be formed by metaphorical transfer, phonologically resemble a name and refer to the activity or the past of the nicknamed person. They convey the author’s attitude towards the object and express a negative characteristic of personality or behaviour.
POLITENESS STRATEGIES IN TRANSLATION OF FICTION (BASED ON ENGLISH TRANSLATIONS OF WORKS BY M. M. ZOSHCHENKO)
Authors:   St. Petersburg State University, Shevchenko Evgenia N. , Kudrya Svetlana V. ,   St. Petersburg State University
Published: November 2024

This paper examines politeness strategies in the translation of fiction, focusing specifically on English translations of works by M. M. Zoshchenko. It employs P. Brown and S. Levinson’s politeness theory to analyze how translators manage politeness phenomena, face-threatening acts, and the negotiation of social norms within literary contexts. This paper aims to provide new insights by exploring how the unique cultural subtexts and diverse character portrayals in Zoshchenko’s works influence the translation process. Unlike previous studies that broadly address the challenges of literary translation and cultural authenticity, this research specifically delineates how politeness is integrated into narrative communication, offering a novel perspective in translation studies. Through this approach, the paper contributes to a deeper understanding of the interaction between language, culture, and social etiquette in translated literary works.
THE PLACE AND ROLE OF ABORIGINAL LANGUAGES OF AUSTRALIA IN THE NATIONAL LANGUAGE POLICY DEVELOPMENT
Authors:   Siberian Federal University, Grishaeva Elena B.
Published: November 2024

The article features Aboriginal languages of Australia through a wider sociocultural issues and sociopolitical events from a diachronical perspective. Although there is a growing literature on multiculturalism and multilingualism in contemporary Australia, there are few studies on indigenous languages and their social functions throughout a rather short history of Australia as a young state in the South Pacific region. This study identifies the aim to focus on multi-component and heterogeneous character of national language policy and planning of Australia and to translate it into a set of objectives: to reflect a social and functional differentiation of indigenous languages; to reveal a controversial social attitude of white Australian population towards local languages and cultures which tailored in their extermination. The paper adds to existing research through a description of a number of issues related to attitudes of institutionalized bodies towards Aboriginal languages and cultures and their political decisions in the frames of the national language policy development by the end of 1980s. Linguistic and historical overviews on indigenous peoples, having been collected and presented by enthusiasts: linguists, topographers, clergymen and police officers in 19th–20th centuries, cemented a sociocultural profile of Australian identity and charted the evolution of attitudes towards Aboriginals and their languages. Along the broad continuum, the research literature shows a link not only between language and culture but also between language and identity. National Language policy in Australia was adopted in 1987. Indigenous languages were placed among other groups of languages forming a rich palette. Unique ethnic profile of the Australian society as well as its linguistic diversity created traumatic controversies in the field of the Australian nation self-identification and ambiguous attitude to indigenous languages and cultures. The paper also investigates factors that had led to extermination and a complete death of the majority of Aboriginal languages. Currently, sociologists of language and political circles support language vitality and indigenous cultures. They maintain bilingual educational programs at schools, publishing primers and glossaries, legends and fairy tales. TV and radio broadcasting services support the feeling of being proud to be able to speak native indigenous languages in every day interactions, and promote their further use as a major means of in-family communication.
SYMBOL STRUCTURE AND ALLEGORY AS OBJECTS OF ETHNO-TRANSLATION
Authors:   Kh. Zhubanov Aktobe Regional University, Idrissova Elmira T.
Published: November 2024

This study analyses the visual structure of the Old Irish poem ‘Cros Chríst’, believed to have been written in the 10th century, and is an example of a lorica — a Christian hymn for a believer’s protection. The objective is to construct a visual structure for an Old Irish poem, specifically ‘Cros Chríst’, which can be used to analyse other Old Irish poems. To achieve this goal, it is necessary to demonstrate through intermediate analysis that the visual structure of the poem ‘Cros Chríst’ unfolds at multiple levels simultaneously. These levels include verbal (word-level analysis), audial (analysis of auditory techniques expressed visually in the text, such as Old Irish alliteration with external expression), and material (analysis of the text’s location in the manuscript). The text discusses various factors that can influence the interpretation of a poem, including drawings, marginal glosses, comments, and the font used. It also mentions synesthetic associations and how a reader-viewer may interpret the poem. The research findings indicate that the poem’s visual structure, including grammatical and graphic parallelism, as well as the use of anaphors, epiphoras, and circle forms, contribute to the formation of a coherent image of both the individual and the world, moving from the specific to the general. Furthermore, the poem symbolically represents the cross as a talisman, which can manifest in both tangible and intangible forms. This study provides a new perspective on the interpretation of Old Irish poetic texts by utilising medieval manuscripts and constructing a multilevel visual structure of a poem.
CULTURAL AND NATIONAL IDENTITY: NATIONAL SELF-IDENTITY AND TRANSLATION STRATEGIES
Authors:   L. N. Gumilyov Eurasian National University, Urazayeva Kuralay B.
Published: November 2024

Ethnic translation is a field of study that highlights the significance of cultural and national identity as a component of translation strategy. It is a prerequisite for successfully integrating the original text into the host culture and achieving authenticity and accuracy in translation. Comparing the original text with its translation enables us to identify the reasons for any discrepancies. These discrepancies can be attributed to the preservation or transformation of cultural and national identity. The first reason is the structure of the rhetorical ideal, which consists of the ideal speaker and the ideal speech, as understood in light of scientific ideas. The second reason is the selection of speech influence techniques in both the original and translated texts. Additionally, the methods used to convey Kazakh ethical representations and norms of behaviour play a crucial role in achieving a ‘harmonising dialogue’. The study of the rhetorical ideal in relation to the national constants of Kazakh national and communicative consciousness serves as the foundation for examining the techniques used to create a national worldview in both the original text and its translation. This analysis also explains the differences between the linguistic personalities of the author and the translator (secondary linguistic personality). An interesting object of study is Russian translations of zhyrau poetry, which were translated word-for-word by Kazakh poets writing in Russian, namely A. Kodar and O. Zhanaidarov. The rhetorical ideal’s dominant values are explained culturally and nationally through the use of proverbs, idioms, symbols, and mythological poetics in the national conceptosphere and linguistic expressions. The author’s conceptosphere employs allegory, poetic syntax devices, and an imaginary world. The text has been edited for objectivity, comprehensibility, conventional structure, clear and objective language, format, formal register, structure, balance, precise word choice, and grammatical correctness. The secondary linguistic personality of the translator considers the otherness of the Other as an important aspect of identity manifestation. It is important to give special consideration to the category of ‘imaginary world’. This approach helps to understand the historical and cultural conditions that affect effective communication between the poet and the addressee.
Hydrological response to climate and land use and land cover change in the Teesta River basin
Authors: Rahman Syadur , Islam A. K. M. Saiful
Published: November 2024

The Teesta basin is shared by Bangladesh and India, holds significant importance in the bilateral relationship, and sustains the livelihoods of over 30 million people in Bangladesh. Employing a cellular-automata model (CA), we accurately estimate LULC for the 2020s and projected for the 2050s and 2080s. A semi-distributed hydrological model, Soil Water Assessment Tool (SWAT), is used to generate flow for the base period (1995–2014), the near future (2035–2064), and the far future (2071–2100). SWAT model is forced by eight general circulation models (GCMs) under two socioeconomic pathways (SSP245 and SSP585). The CA-Markov prediction indicates LULC changes, especially increased agriculture and settlements by 76 and 42%, and decreased forest and water by 13 and 36%, respectively, which are expected by 2050s and will influence discharge patterns. This results in additional discharge increases of 4% (–8 to 5%) for SSP245 and 5% (–8 to 10%) for SSP585 scenarios during wet seasons. In the far future, monsoon flow will increase by 13% (0.4 to 23%) for SSP245 and 52% (–29 to 151%) under SSP245 and SSP585. A marginal change in winter flow was shown by –6% (–16 to 4%) reduction under SSP245 and –13% (–64 to 63%) under SSP585 reduction in the 2080s.
Safe drinking water: to what extent are shallow wells reliable?
Authors: Breternitz Bruna Suellen , Dropa Milena , Martone-Rocha Solange , Ferraro Pedro Smith Pereira , dos Santos Peternella Francisca Alzira , Lopes da Silva Miriam , Razzolini Maria Tereza Pepe
Published: November 2024

Our study investigated the presence of Cryptosporidium hominis-parvum-meleagridis and Giardia duodenalis in shallow wells used for drinking water (DW) in a rural area. Also, bovine feces were collected from their vicinity. Our findings highlight significant potential risks associated with these pathogens in DW sources. Due to the COVID-19 pandemic, samples were collected in two phases: September/2019 to March/2020 and October/2021 to April/2022. Water samples (n = 69) and feces (n = 13) were collected biweekly and analyzed using the USEPA 1623.1 method and molecular tools for species identification, and feces by direct DNA extraction. During the first phase, oocysts and cysts were detected at frequencies ranging from 9.1 to 41.7 and 27.3 to 83.3, respectively. In the second phase, oocyst frequencies ranged from not detected to 25%, while cyst ranged from 18.2 to 83.3%. Escherichia coli concentrations were significant at all collection points. C. hominis-parvum-meleagridis and G. duodenalis were notably detected in bovine feces. Our study revealed the presence of anthropogenic parasites and E. coli in DW sources intended for human consumption. These findings underscore the urgent need for preventive measures to ensure safe DW and prevent future contamination. Effective water quality surveillance is crucial in this regard.
Cuidados na inserção do cateter venoso central em recém-nascidos: protocolo de revisão de escopo
Authors: Torrezan Milena Gabriele , Pires Andressa Ayumi Kuriki , Araujo Juliane Pagliari , Zani Adriana Valongo
Published: November 2024

Objetivo: descrever a sistematização acerca do mapeamento e sintetização as evidências científicas disponíveis em relação aos cuidados adotados por enfermeiros na inserção do cateter venoso central de inserção periférica em recém-nascidos. Metodologia: Trata-se de um protocolo de revisão de escopo, elaborado conforme recomendações do Instituto Joanna Briggs. A busca será realizada nas bases de dados Biblioteca Virtual em Saúde, Excerpta Medica dataBASE, National Library of Medicine, Scientific Electronic Library Online, Scopus e Web of Science, Catálogo de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior e Google Scholar sem restrição de idioma ou temporal. A seleção dos estudos será realizada por dois revisores independentes e a extração de dados se dará por meio de um formulário construído com base no objetivo deste estudo. Os dados extraídos serão apresentados em diagramas ou tabelas e analisados de forma descritiva e qualitativa. Conclusão: Este protocolo norteará o desenvolvimento do estudo que fará o mapeamento dos cuidados adotados pelos enfermeiros para a inserção do cateter central de inserção periférica em recém-nascidos. Espera que as evidências encontradas possam contribuir para a assistência de qualidade ao recém-nascido.
Palavras-Chave: Cuidados de Enfermagem; Cateterismo Periférico; Cateterismo Venoso Central; Recém-Nascido; Enfermagem Neonatal.
Práticas de cuidado da enfermeira no pré-natal sob a ótica de gestantes
Authors: Santana Tayná Valasques , Dias Joana Angélica Andrade , Rodrigues Vanda Palmarella , Santos Flavia Pedro dos Anjos
Published: November 2024

Introdução: O presente estudo teve como objetivo descrever as práticas de cuidado das enfermeiras no pré-natal da Saúde da Família. Materiais e métodos: Trata-se de um estudo qualitativo, realizado com 18 gestantes acompanhadas em Unidades de Saúde da Família da zona urbana de um município do interior baiano. Os dados foram coletados por meio da entrevista semiestruturada e analisados com base na técnica de análise de conteúdo, modalidade temática. Resultados e discussão: Os resultados evidenciaram que as práticas de cuidado da enfermeira no pré-natal são norteadas pelo diálogo, orientações e realização de procedimentos técnicos. Também foram identificadas contradições no que se refere ao acesso à marcação de consultas, exames complementares e aos medicamentos relativos ao pré-natal. Considerações finais: Logo, torna-se relevante avaliar a organização dos serviços ofertados no pré-natal, de modo a atender as expectativas, inquietações e anseios das gestantes, que evidenciaram a necessidade da enfermeira realizar sua prática educativa não apenas individual, mas também de forma coletiva.
Palavras-chave: Pré-natal; Enfermagem; Estratégia Saúde da Família; Saúde da Mulher.
Participação dos discentes de graduação em enfermagem no combate a pandemia de covid-19 e seu impacto na formação profissional
Authors: Santos Rafaela Liz de Castro dos , Ferreira Rejane Eleuterio , Prado Gabriela Silva dos Santos , Viana Verônica Pinheiro , Fonseca Paula Isabella Marujo Nunes
Published: November 2024

A covid-19 suscitou a necessidade de adesão, adaptação de modalidades de ensino não convencionais e modificações no aprendizado prático para preservar a saúde de discentes e docentes. Contudo, alguns estudantes de enfermagem dispuseram da oportunidade de atuar diretamente contra a pandemia de covid-19 de baixa complexidade. Logo, os objetivos deste trabalho foram comparar a vivência entre os alunos que tiveram e que não tiveram aula prática em um setor que realiza testagem e diagnóstico de covid-19; e identificar, sob a óptica dos alunos, se houve diferença na formação, devido às aulas práticas no setor que realiza testagem e diagnóstico de covid-19. Trata-se de um estudo de abordagem qualitativa com objetivo descritivo realizado com graduandos do 5º período de enfermagem de uma universidade federal que tiveram ou não oportunidade de estagiar no setor em foco. Utilizou-se como instrumento um formulário contendo perguntas abertas e fechadas e disponibilizado remotamente. Observou-se nos resultados que os alunos que estagiaram no setor em questão obtiveram experiências positivas, desenvolvendo habilidades e competências. Todavia, o outro grupo expressou desejo de vivenciar o setor e não considera estar preparado para atuar em cenário pandêmico somente com os conteúdos teóricos ofertados. Estudos apontam a prática como meio para a inserção no mercado de trabalho, e sua ausência como um dificultador. Assim, entende-se que a vivência nesse setor foi um diferencial no processo de formação, pois permitiu a atuação de discentes em um contexto singular, a realização de procedimentos e sentimento de preparo para intervir em futuros cenários pandêmicos semelhantes.
Palavras-chave: Covid-19; Educação em Enfermagem; Pandemias.
Efeitos tardios do tratamento da leucemia linfoblástica aguda em crianças
Authors: Vieira Louise Moreira , Costa Gabriella Pacheco , Silva Marina Corrêa da , Souza Maria Cristina Almeida de , Borges Renato Franco
Published: November 2024

A leucemia linfoblástica aguda (LLA) é um tumor hematológico maligno, sendo o câncer mais prevalente na infância. Avanços no tratamento da LLA tem contribuído para aumento da sobrevida dessa população. No entanto, em longo prazo, foram demonstradas diversas complicações decorrentes da terapia da LLA. O objetivo deste artigo é abordar as possíveis complicações relatadas na literatura decorrentes do tratamento de LLA. Trata-se de uma revisão da literatura, realizada por meio de uma busca por trabalhos nas plataformas SciELO, PubMed e LILACS. Como resultado, 23 artigos foram incluídos após a aplicação de critérios de inclusão e exclusão. Através dos estudos analisados, foram observadas diversas complicações após o tratamento curativo da LLA em crianças. Dentre os efeitos a longo prazo mais comuns, pode-se citar tumores secundários e toxicidade cardíaca. Outras alterações, como acometimento neurológico e alterações musculoesqueléticas, também foram citadas. Os efeitos tardios do tratamento da LLA são significativos e com grande potencial de limitação funcional em indivíduos de idade reprodutiva. Dessa forma, é fundamental a criação de diretrizes e a disseminação de conhecimento para os profissionais de saúde em relação aos jovens que passaram por esses tratamentos.
Palavras-Chave: Efeitos Tardios; Infância; Leucemia Linfoblástica Aguda.
Assistência de enfermagem e complicações pós-operatórias imediatas
Authors: Silva Luciana Martins da , Sampaio Carlos Eduardo Peres , Conceição Santoro Deyse , Rodrigues Risi Lisandra
Published: November 2024

Introdução: O período pós-operatório inicia-se com a saída do paciente da sala de cirurgia, sendo dividido em: recuperação anestésica (até sua alta para unidade), imediato (primeiras 24 horas), mediato (após 24 horas até a alta hospitalar) e tardio (término do período pós-operatório mediato até um ou dois meses, com completa cicatrização do sítio cirúrgico. Materiais e Métodos: Trata-se de um estudo observacional, prospectivo, com abordagem quantitativa. O estudo foi realizado em um Hospital Universitário localizado no município do Rio de Janeiro. A coleta de dados ocorreu no período de abril a agosto de 2022. O tratamento dos dados foi realizado no programa IBM SPSS 25 Statistcs for Windows. Foram utilizados o teste de correlação de Spearman, para as associações entre as variáveis de interesse e o teste de Mann-Whitney, para as comparações das variáveis de estudo por sexo. Resultados e discussão: Os resultados demostraram que a dor é a complicação mais comum (61,32%) dos casos, seguido da sede (54,72%) e náuseas (16,04%). O grupo masculino apresentou valores maiores da idade (p<0,05) quando comparado ao grupo feminino. No entanto, o grupo feminino apresentou maior quantidade de complicações (p < 0,05). O tempo médio de jejum foi de 10,73 horas e o estudo encontrou correlações positivas e significativas (p < 0,05) entre tempo de jejum e quantidade de complicações. Considerações finais: Análises acerca dos resultados obtidos neste estudo possibilitam elaborar intervenções de enfermagem para pacientes em pós-operatório imediato, formando um sentido para estudos focados na validação de intervenções de melhorias futuras.
Palavras-Chave: Centro Cirúrgico; Assistência de Enfermagem; Complicações Pós-operatórias; Cuidados Perioperatórios; Recuperação Pós-Anestésica.
Developing Generalizable Scoring Functions for Molecular Docking: Challenges and Perspectives
Authors: Quiroga Rodrigo , Villarreal Marcos
Published: November 2024

Structure-based drug discovery methods, such as molecular docking and virtual
screening, have become invaluable tools in developing novel drugs. At the core of these
methods are Scoring Functions (SFs), which predict the binding affinity between ligands
and protein targets. This study aims to review and contextualize the challenges
and best practices in training novel scoring functions to improve their accuracy and generalizability
in predicting protein-ligand binding affinities. Effective training of scoring
functions requires careful attention to the quality of training data and methodologies.
We emphasize the need for robust training strategies to produce consistent and generalizable
SFs. Key considerations include addressing hidden biases and overfitting in
machine-learning models, as well as ensuring the use of high-quality, unbiased datasets
for both training and evaluation of SFs. Innovative hybrid methods, combining the advantages
of empirical and machine-learning approaches, hold promise for outperforming
current scoring functions while displaying greater generalizability and versatility.
Investigating the Factors Affecting Sexual Myths in Women and Men Based on the Biopsychosocial Model: A Scoping Review
Authors: Roushan Faezeh Habibnejad , Azizi Marzieh , Habibi Farangis , Khani Soghra
Published: November 2024

Background:

Sexual myths are mainly devoid of any substantial evidence and are passed
on by word of mouth. Myths about sexuality may thus diminish the quality of sexual activities,
cause sexual dysfunctions, including erectile dysfunction (impotence), vaginismus, difficulty reaching
an orgasm, and premature ejaculation, and make individuals feel dread, anxiety, and failure or
inadequacy, which can have adverse effects on their sexual identity.

Objective:

This study investigated the factors affecting sexual myths in women and men based on
the biopsychosocial model.

Methods:

In this scoping review, the research databases of PubMed, Google Scholar, Magiran,
PsycINFO, IranDoc, Ovid, ProQuest, Scientific Information Database (SID), and the Cochrane Library
were systematically searched. For this purpose, a systematic search was conducted to retrieve
the relevant articles from November 3 to 21, 2023, using the keywords of “sexual myth, sexual beliefs,
wrong beliefs, dysfunctional sexual beliefs, sexuality, opinions, and associated factors.” The
Newcastle-Ottawa Scale (NOS) further evaluated the quality of the included studies. The data were
then extracted from all the articles that met the eligibility criteria based on the study objectives.

Results:

In total, 12 articles were reviewed, whose data were grouped into three general categories,
viz., (i) biological factors (i.e., age and gender), (ii) psychological factors (that is, sexual dysfunction,
political opinions, opinions on virginity), and (iii) social factors (namely, educational attainment,
occupation, place of residence, marital status, type of marriage, age at marriage, premarital
sexual experience, parents’ educational attainment, spouse’s educational attainment, number of
children, parent’s employment status, spouse’s occupation, primary source of information about sex
and feelings about sexual conversations, information about sexual life, academic department, sexual
health assessment, and religious beliefs).

Conclusion:

Biopsychosocial factors could significantly affect sexual myths; therefore, considering
their mediating role in providing sex education to women and men is crucial.
Foot Reflexology for Managing Menopausal Symptoms in Women: A Systematic Review and Meta-Analysis
Authors: Maghalian Mahsa , Alikamali Maryam , Aslanpur Farzaneh , Mirghafourvand Mojgan
Published: November 2024

Background:

Menopause can cause a variety of unpleasant symptoms, such as hot flashes,
night sweats, mood swings, and sleep disturbances. Although hormone replacement therapy is
frequently utilized to help manage these issues, long-term use of this treatment approach carries certain
potential risks.

Objective:

This study aims to examine the effects of foot reflexology, a type of massage therapy
that focuses on applying pressure to specific reflex points on the feet, on menopausal symptoms
(primary outcome) and anxiety, fatigue, and depression (secondary outcomes).

Methods:

A systematic electronic search for relevant studies was conducted in PubMed, Scopus,
Web of Science, the Cochrane Library, SID, Magiran, and Google Scholar until September 21,
2023. In addition to the electronic database searches, manual searches were also performed. This
manual search process included scanning the reference lists of the included studies and handsearching
key journals in the topic area. The risk of bias was assessed via the RoB 2.0 and ROBIN-I
tools. Heterogeneity was evaluated via the I² statistic, and in cases of high heterogeneity, a random
effects model was used instead of a fixed effects model. Subgroup analyses were performed for the
primary outcome on the basis of menopausal symptoms (vasomotor/psychosocial/physical/sexual).
The certainty of evidence was assessed via the GRADE approach.

Results:

A total of 186 articles were retrieved from database searches, and an additional 9 articles
were identified through manual searches. Ultimately, 8 studies were included in the systematic review,
and 6 studies were included in the meta-analysis. The meta-analysis revealed that foot reflexology
had a significant effect on menopausal symptoms, with an average reduction of 3.41 points
on the associated measurement scale (95% confidence interval (CI): -4.81 to -2.01; low-certainty
evidence). It also significantly reduced fatigue, with an average reduction of 5.84 points (95% CI: -
11.61 to -0.06; very low-certainty evidence). However, there was no significant impact on anxiety
(SMD: -0.89, 95% CI: -1.96--0.18; very low-certainty evidence) or depression (SMD: -0.73, 95%
CI: -1.80--0.34; very low-certainty evidence) compared with the control group.

Conclusion:

The present study demonstrated that the use of foot reflexology as a nonhormonal and
noninvasive intervention led to a significant reduction in menopausal symptoms and fatigue among
women. Given the limited number of studies available in this area and the low to very low-level
certainty of the evidence for the desired outcomes, further research with appropriate methodologies
to ensure accurate conclusions in this field is strongly recommended.