bluuebunny/crossref_metadata_2025 huggingface dataset:
FACTORS FOR THE FORMATION OF FINANCIAL SECURITY FOR THE DEVELOPMENT OF DOMESTIC ENTERPRISES ON THE BASIS OF INNOVATION
Authors:   Lviv Ivan Franko National University, RUSHCHYSHYN Mariia
Published: June 2023

Attention has been updated to the problems of forming financial support for the implementation of investment and innovation projects of enterprises, which aim to ensure their innovative development. Therefore, the purpose of the study is to identify the composition and analysis of the factors of the formation of financial support for the development of enterprises in Ukraine on an innovative basis. A typology of the factors of attracting financial support for investment and innovation goals was carried out in two directions: (1) internal resources and capabilities of economic entities, (2) external sources of accumulation of financial resources. Among the internal factors, the influence of such as the financial and economic condition, results and business activity of enterprises, availability of internal investment capital, innovative and technological activity of business entities, financial security and protection of intellectual property objects of innovatively active enterprises was analyzed. According to external factors, such as the development of the financial and credit system of the region, the activities of venture funds, business angels, the state of development of innovative infrastructure and the business environment were analyzed. The conditions that determine the specified factors of financial support for the innovative development of domestic enterprises are characterized, as well as their current state and the main problems that prevent the full involvement of financial and investment assets sufficient for the full-fledged conduct of innovative and technological activities by economic entities of Ukraine are identified. The scientific novelty of the research results lies in the further development of the methodological and applied principles of classification and typology of the factors of the formation of financial support for the activation of innovative activities of enterprises. The applied value of the research results lies in the possibility of identifying the available factors for the formation of financial and investment support for innovative and technological growth of business entities.
STABILIZATION MEASURES TO IMPROVE THE ECONOMIC AND ENVIRONMENTAL MANAGEMENT OF OIL AND GAS EXTRACTION ENTERPRISES
Authors:   Ivano-Frankivsk National Technical University of Oil and Gas, FADYEYEVA Iryna
Published: June 2023

The article substantiates the necessity of implementing organizational, technological and economic measures of environmental orientation, the purpose of which is to reduce environmental damage and significant economic losses, and therefore to improve the financial condition of enterprises. The latest scientific research in the direction of solving the problems of assessing the levels of environmental danger and related environmental risks of oil and gas production enterprises is analyzed. The importance of solving economic and environmental problems of oil and gas enterprises is shown on the example of an oil and gas production enterprise. Systematized external factors of natural, man-made, social origin as sources of danger and threats to the enterprise. The sequence of formation of the mechanism for preventing the occurrence of ecologically dangerous risk-events, the purpose of which is to identify the sequence of events leading to accidents, as well as the development of scenarios for the occurrence and development of accidents and the assessment of the probability of their occurrence, is given. Stabilization measures to improve the economic and environmental management of oil and gas production enterprises are proposed. The use of the obtained research results will allow to optimize management decisions during strategic planning by comparing the specifics of the oil and gas production enterprise with strategic changes in the external environment.
STATISTICAL SECURITY OF ECONOMIC MANAGEMENT
Authors:   State Statistics Service of Ukraine, HRYTSUN Viktoriia
Published: June 2023

Modern integrated economic statistics is a set of economic and statistical data that reflect a consistent and holistic picture of economic activity for political, commercial and other analytical purposes. In analyzing the historical aspect of the emergence and development of statistical practice, we have shown that its origin occurred around the time when the state emerged. There is information about the elementary recount (census) of population and land, which was conducted several millennia ago. With the formation of a centralized state and especially with its development, the scope of statistics has expanded significantly. It is established that the statistical support of effective development of enterprises of Ukraine in the scale of a particular industry can be realized according to official statistics, namely: statistical observations of the volume of sold industrial products and operating costs of sold products. It is emphasized that today the volume and structure of data presented on the official website of statistics of Ukraine, is considered insufficient for full information support of management processes of industrial enterprises. The approaches of scholars to the interpretation of the role of statistical methods of analysis for successful economic management are considered. The basic mathematical and statistical methods are listed and their short characteristic is given. It is established that the profitability indicator is chosen as a general indicator of efficiency and technological level of enterprises of the studied industries. Construction of the economic and mathematical model of profitability of products of separate industries made it possible to reveal production reserves to increase the efficiency of the enterprises. For mechanical engineering it means reducing the capital intensity of products used funds (depreciation). For metallurgy it means a reduction in material and labor intensity of products. For the production of chemical products it is reducing material consumption. When choosing statistical methods for studying socio-economic phenomena, it is necessary to take into account their interconnectedness and interdependence. Based on the results, the priority for the development of management decisions for the effective development of processing enterprises should be to increase the degree of processing of raw materials (to increase the technological level of production), increase productivity of fixed assets and increase final consumption.
MARKETING ASPECTS OF THE APPLICATION OF “FORMULA 4 K” IN THE IMPLEMENTATION OF GRANT PROGRAMS
Authors:   Khmelnytskyi Cooperative Trade and Economic Institute, KOVALCHUK Svitlana
Published: June 2023

The higher school of Ukraine has undergone significant transformational changes in recent years, initially due to the processes caused by the “Covid-19” pandemic in 2019-2021, and since February 24, 2022, the military aggression of the Russian Federation against Ukraine has been added to the destructive factors of influence. . Factors that had a significant impact o n the development of higher education in recent years include: 1) a decrease in the quality of secondary education as a result of existing restrictions, which requires additional efforts on the part of professors and teachers of higher education institutions (HEIs) in the formation of professional competences according to the educational programs chosen by the applicants; 2) the formation of the effect of “reduced concentration of attention” among students – representatives of the “Z” and “ALPHA” generations, who grew up on digital technologies and perceive them as an integral part of their real life, began to enter universities; 3) limitation of work in classrooms, and therefore: reduction of direct contacts of students with teachers, which does not allow the full use of existing innovative learning technologies, and also requires greater independence and responsibility from students and the formation of specific skills among the teaching staff; 4) the influence of stress factors on the psycho-emotional state of both applicants and teachers, hence the urgent need to conduct special classes with professional psychologists to overcome them (unfortunately, not every institution of higher education has such specialists); 5) physical destruction of educational, economic and infrastructure institutions of Ukraine, which led to their relocation to safer regions of the country, and therefore increased competition in the central and western regions, etc. But crisis phenomena are usually the best stimulus for development and innovation, prompting the search for non-standard responses to overcome them. One of the directions for overcoming crisis phenomena and their consequences for the system of pre-higher and higher education and the economy as a whole can be the application of the “4K Formula”, because it is this approach to education that is focused on the formation of skills in the individual, which are needed not only now, but also will be in demand in the future.The article discusses the marketing aspects of the application of the “4 K formula” in the implementation of the grant project “Expanding the horizons of opportunities for Khmelnytskyi residents and IDPs “Khmelnytskyi: Cooperation & Training & Integration”. Theoretical approaches to the formation of the “4K” concept were considered and analyzed.
INFORMATION TECHNOLOGIES IN ACCOUNTING AND AUDIT: PROBLEMS AND PERSPECTIVES IN THE DIGITAL ECONOMY
Authors: HEVLYCH Larysa , HEVLYCH Ivan ,   Vasyl’ Stus Donetsk National University
Published: June 2023

Researching the problems of digitalization of accounting and auditing in modern Ukraine is a serious scientific and practical task, considering the challenges of the post-war domestic economy and trends in the development of the accounting profession in the world. The purpose of the work is to study the current state and the nearest prospects of the use of modern information technologies in the accounting and auditing activities of Ukrainian economic entities from the point of view of identifying problems and developing ways to solve them. The work examines the requirements for modern accounting software products of domestic enterprises, highlights the financial and organizational problems of realizing the intention of automation, proposes state support measures for small and medium-sized enterprises in relation to the development of standard software with industry configurations, training of personnel domestic higher education institutions. Popular programs of foreign practice of automating the audit process were studied, TeamMate+ Audit, CaseWare IDEA, Wolters Kluwer CCH Audit Accelerator. The influence of the state of war on the domestic audit activity is identified, the main problems are highlighted and the directions for their solution are proposed through the stimulation of audit activity subjects to digitalization by state bodies and bodies of professional self-governance. The essence of modern information technologies, which are trends in the development of the accounting profession in the world, is also considered: cognitive technologies, predictive analytics, cloud platforms. Based on the results of the study, conclusions were drawn. As directions for further research, the identification of problems in the implementation of the bachelor’s educational program “Digital accounting and taxation” of Vasyl’ Stus Donetsk National University from the point of view of solving the issues is proposed.
Exploring the students’ perception on the use of teaching factory method in English learning
Authors:   Politeknik Negeri Jember, Indonesia, Indrastana Nodistya Septian , Dewangga Vigo ,   Politeknik Negeri Jember, Indonesia, Rinda Renata Kenanga ,   Politeknik Negeri Jember, Indonesia
Published: June 2023

The Economic development of a country is determined by the main factor, the human resources competitiveness. In preparing competent human resources, the strategic program to be undertaken by the government is to align competencies of vocational higher education students with the needs of industrial competence. As a result, link and match between industry and higher-level vocational education could be achieved. The solution to prepare students to have competencies that are in accordance with industrial competence is by giving teaching factory (TEFA) method. It is a concept that aims to align manufacturing teaching to the needs of industrial practice. This study focuses on students’ perceptions on the use of teaching factory method in English learning, especially English for hotel and restaurant. This study adopts qualitative approach. Data were collected using questionnaires and interviews. The findings in this study reveal students' perceptions and responses on the use of teaching factory method. It shows that many of the students feel enthusiasm in attending English for hotel and restaurant using teaching factory method. It also shows that many of the students express that learning in English for hotel and restaurant encourage them to be actively participated in learning process. It can be concluded that most of the students have a positive impression about the use of teaching factory method in English learning, especially English for hotel and restaurant.
The attitudes characterizing humans and giants in two folktales from central Sulawesi
Authors:   Universitas Sanata Dharma, Indonesia, Manggala Simon Arsa
Published: June 2023

This paper aims at providing a critical alternative framework for reading folktales from Indonesia from linguistic viewpoints. The choice of linguistic items in tales is significant to investigate since folktales serve as a tool to teach values to children, and they share similar patterns. By utilizing the appraisal analysis, this research attempts to discuss the characterization of humans and giants in the English version of two folktales from Central Sulawesi, a province in Indonesia. The folktales are entitled Kolombio bo Ngana Pailu (The Giant and the Orphan) (Lasipi, 1999) and Topeande (The Man-eating Giant) (Kareba, 1999). By examining the use of affect, judgement, and appreciation, this research figures out that negative attitudes dominantly characterize both human and giant characters. Out of 89 linguistic items in the data, human characters are characterized by 43 negative attitudes, while giant characters are characterized by 20 negative attitudes. Interestingly, by the positive attitudes, the human characters are predominantly depicted as superior in their cognitive abilities and skills. It provides the depiction of the way the two folktales present the human and giant characters. Meanwhile, giants are more dominant than humans in terms of their physical power and strength. This research also suggests that linguistic analysis can support storytelling activities by providing in-depth, objective discussions on the tales.
Hormonal contraception in terms of effect on the hemostasis system
Authors:   Novosibirsk State University, Novosibirsk, Russian Federation, Kudinova E.G.
Published: June 2023

Aim: to study the hemostasis indicators in female patients with hyperandrogenism (HA) and menstrual disorders (MDs) during combined oral contraceptive (COC) intake, depending on the presence of undifferentiated connective tissue displasia (UCTD). Patients and Methods: the study results of 28 female patients with HA and MDs were divided into 2 groups: group 1 — 22 patients (mean age 22.1±3.2 years) with UCTD, group 2 — 6 patients (mean age 20.5±1.8 years) without UCTD. The content of hormones in the blood (on the 2nd–3rd day of the menstrual period), the parameters of hemostasis before and after 1 month of COCs intake, and the level of homocysteine were determined in all patients. Results: the analysis revealed an increase in the levels of platelet activation markers, coagulation link and fibrinolysis. During COCs intake, an increase in the fibrinogen content was noted in patients of both groups, which, however, did not exceed the reference values. During the correlation analysis, it was found that in groups 1 and 2, the parameters of the fibrinogen baseline, D-dimer and the corresponding indicators after 1 month of COCs intake had a strong correlation with each other (r=0.845, r=0.864). However, group 1 had higher levels of fibrinogen and fibrin degradation products (D-dimer) (p<0.0001) versus those in group 2. The study on the trend of prothrombin time (PTT) and activated partial thromboplastin time (APTT) during COCs intake in female patients with HA and UCTD revealed an acceleration of indicators (p<0.01) versus those before COCs intake. At the same time, the change in blood clotting markers was not realized by episodes of thrombosis in any of the patients. Conclusion: patients with UCTD had changes that characterized the activation of thrombogenesis. When planning hormonal contraception, it is necessary to single out a group of female patients with HA and signs of UCTD as the most vulnerable in relation to an increased risk of thrombogenic events. KEYWORDS: hyperandrogenism, combined oral contraceptive, thrombosis, connective tissue dysplasia, hyperhomocysteinemia. FOR CITATION: Kudinova E.G. Hormonal contraception in terms of effect on the hemostasis system. Russian Journal of Woman and Child Health. 2023;6(2):130–137 (in Russ.). DOI: 10.32364/2618-8430-2023-6-2-130-137.
Achromatic vaginal melanoma. A rare clinical report
Authors:   City Clinical Hospital No. 52, Moscow, Russian Federation, Shevchenko N.A. , Varyasin V.V. ,   City Clinical Hospital No. 52, Moscow, Russian Federation, Tsidaeva I.G. ,   City Clinical Hospital No. 52, Moscow, Russian Federation, Polikarpova O.V. ,   City Clinical Hospital No. 52, Moscow, Russian Federation, Ayazova A.A. ,   Moscow City Oncological Hospital No. 62, Moscow, Russian Federation
Published: June 2023

Melanoma is "a queen of malignant tumors" and one of the most rare and aggressive types of cancer. At the same time, it is the most well- known malignant tumor. The word "melanoma" is derived from the Greek melas, melanos means “dark, black.” However, there is also an amelanotic type of melanoma. Melanoma is associated with skin disorders, but can also occur in multiple organs and tissues: the choroid and iris, urogenital tract (vulva, vagina, uterine cervix, penis), mucous membrane of the gastrointestinal tract, meninges, lungs, etc. This is related to the fact that all these organs have melanocytes (pigment-producing cells) from which melanoma develops. Vaginal melanoma or "mucosal melanoma" is a very rare and aggressive neoplasm accounting for less than 10% of malignant tumors of female genital organs and 0.3% of all melanoma cases. Clinical and pathological characteristics of this tumor are understudied, diagnostic tools are scarce, and an optimal method of treatment has not been developed. Therefore, it is important to share experience and clinical reports on this disease. The authors present a rare and complicated case of the disease — achromatic vaginal melanoma. KEYWORDS: vaginal melanoma, achromatic melanoma, neoplasms, women, diagnostics, treatment. FOR CITATION: Shevchenko N.A., Varyasin V.V., Tsidaeva I.G. et al. Achromatic vaginal melanoma. A rare clinical report. Russian Journal of Woman and Child Health. 2023;6(2):145–148 (in Russ.). DOI: 10.32364/2618-8430-2023-6-2-145-148.
Expert Council: promising areas of systemic enzyme therapy in gynecology
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Dobrokhotova Yu.E. , Khryanin A.A. ,   Novosibirsk State Medical University, Novosibirsk, Russian Federation, Shikh E.V. ,   I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Karakhalis L.Yu. ,   Russian University of Peoples' Friendship, Moscow, Russian Federation, Ordiyants I.M. ,   Kuban State Medical University, Krasnodar, Russian Federation, Kogan E.A. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Yakimova A.V. ,   Novosibirsk State Medical University, Novosibirsk, Russian Federation, Korotkikh I.N. ,   N.N. Burdenko Voronezh State Medical University, Voronezh, Russian Federation, Kokhno N.I. ,   LLC “Center of Reproduction and Genetics”, Moscow, Russian Federation
Published: June 2023

The interdisciplinary scientific and practical conference «Expert Council: promising areas of systemic enzyme therapy (SET) in gynecology» under the auspices of the National Association of Obstetricians-Gynecologists and Reproductologists "Women's Health" was held in Moscow on December 02, 2022. The conference brought together specialists from multiple Russian regions. The development of effective treatment algorithms for infection-caused inflammatory diseases in the practices of obstetricians and gynecologists remains relevant in view of the continuous growth of antimicrobial resistance underpinned both by the irrational use of antibiotics and the biofilm-forming ability of infectious agents. The speakers shared their experience of using systemic enzyme therapy (SET) in the combination treatment of inflammatory diseases in obstetric and gynecological practice, as well as in the prevention of fibrous and adhesive complications of pelvic inflammatory diseases (PID) and gynecologic surgeries. It was pointed out that systemic enzyme therapy should be recognized as a justified component of the combination PID treatment which helps to reduce the duration and severity of symptoms due to its proven immunomodulatory, fibrinolytic and antiplatelet effects. The use of SET drugs reduces the duration of all stages of reparative regeneration along with tamping down the inflammatory response. The Expert Council Resolution provides recommendations on using SET in gynecology. KEYWORDS: proteolytic enzymes, pelvic inflammatory diseases, endometritis, adhesions, antibiotic resistance, systemic enzyme therapy. FOR CITATION: Dobrokhotova Yu.E., Khryanin A.A., Shikh E.V. et al. Expert Council: promising areas of systemic enzyme therapy in gynecology. Russian Journal of Woman and Child Health. 2023;6(2):149–156 (in Russ.). DOI: 10.32364/2618-8430-2023-6-2-149-156.
The association between the tendency of the head circumference growth trajectory in neonates (1 month) and the psychomotor development of extremely preterm infants at the age of 3 years
Authors:   Yaroslavl State Medical University, Yaroslavl, Russian Federation, Shcherbakova V.P. ,   Regional Perinatal Center, Yaroslavl, Russian Federation, Mozzhukhina L.I. ,   Yaroslavl State Medical University, Yaroslavl, Russian Federation, Stroyeva L.E. ,   Yaroslavl State Medical University, Yaroslavl, Russian Federation, Kalgina S.E. ,   Yaroslavl State Medical University, Yaroslavl, Russian Federation,   Regional Perinatal Center, Yaroslavl, Russian Federation, Kiselnikova O.V. ,   Yaroslavl State Medical University, Yaroslavl, Russian Federation
Published: June 2023

Aim: to study the association of the head circumference (HC) growth trajectory in extremely preterm neonates (1 month) with the outcomes of psychomotor development by the age of 3 years. Patients and Methods: a retrospective cohort study included 140 children with extremely low birth weight in the Yaroslavl region in the period from 2012 to 2018 and observed up to the age of 3 in the outpatient department for infants of the Regional Perinatal Center. The HC growth trajectory was determined based on the tendency of indicators from the birth to the age of 1 month, expressed as a percentage. The Clinical Adaptive Test / Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS) was used to assess psychomotor development. The outcomes of psychomotor development were defined as the norm, development dissociation (differences in indicators of the CAT/CLAMS and motor skills) and delayed development. Results: the tendency of the HC growth in neonates (1 month) was characterized by three trajectories: slow growth (n=37; 26.4%), catch-up growth (n=69; 49.3%) and rapid catch-up growth (n=34; 24.3%) with significant differences in indicators of psychomotor development at the age of 3 years (p<0.001). More than half (52.9%) of extremely preterm infants with rapid catch-up growth of HC had normal psychomotor development, while in the group with HC delayed growth — only 24.3%. The HC growth trajectory in neonates (1 month) and the outcomes of psychomotor development of children by the age of 3 were influenced by the following: gestational age, birth weight, HC at birth, ventilator length of stay, the presence of bronchopulmonary dysplasia, hemodynamically significant persistent ductus arteriosus, postnatal growth retardation and the method of feeding. Conclusion: extremely preterm neonates (1 month) with HC slow growth are subject to a delay in psychomotor development by the age of 3 years. KEYWORDS: children, preterm infants, head circumference, head circumference growth trajectory, psychomotor development, CAT/CLAMS. FOR CITATION: Shcherbakova V.P., Mozzhukhina L.I., Stroyeva L.E. et al. The association between the tendency of the head circumference growth trajectory in neonates (1 month) and the psychomotor development of extremely preterm infants at the age of 3 years. Russian Journal of Woman and Child Health. 2023;6(2):157–163 (in Russ.). DOI: 10.32364/2618-8430-2023-6-2-157-163.
Abdominal pain masqueraders in preschool and primary-school-age children
Authors:   A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation, Medvedeva E.A. , Khavkin A.I. ,   Yu.I. Veltishchev Research Institute for Pediatrics of the Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: June 2023

Abdominal pain, one of the most common complaints of patients visiting pediatrician and gastroenterologist, is a multifactorial syndrome. Thus, physicians often need to generate challenging differential diagnoses. Thorough gathering of the medical history and physical examination are the best tools for making diagnosis. However, in some cases it is necessary to use laboratory tests and instrumental methods. In some cases, the search for effective treatment of abdominal pain becomes a difficult task requiring a multidisciplinary approach for developing symptom management strategies. The article presents a literature review focused on the issues of acute and chronic abdominal pain in children and summarizes the latest trends in performing patient examination and making differential diagnosis. Emphasis is made on the differential diagnosis of conditions considered as the most common causes of abdominal pain and functional gastrointestinal disorders classified according to Rome IV Criteria. The article elucidates the latest therapeutic approaches to the management of pain abdominal syndrome and considers mechanisms that may be involved in its pathogenesis. KEYWORDS: children, acute abdominal pain, chronic abdominal pain, functional gastrointestinal disorders, irritable bowel syndrome, functional dyspepsia, abdominal migraine, Rome IV Criteria, trimebutine. FOR CITATION: Medvedeva E.A., Khavkin A.I. Abdominal pain masqueraders in preschool and primary-school-age children. Russian Journal of Woman and Child Health. 2023;6(2):175–183 (in Russ.). DOI: 10.32364/2618-8430-2023-6-2-175-183.
Сourse patterns of postnatal cytomegalovirus infection in full-term infants. Cases in clinical practice
Authors:   St. Petersburg State Pediatric Medical University, St. Petersburg, Russian Federation, Panchenko A.S. , Bem E.V. ,   St. Petersburg State Pediatric Medical University, St. Petersburg, Russian Federation, Chumakova G.N. ,   St. Petersburg State Pediatric Medical University, St. Petersburg, Russian Federation, Myznikova I.V. ,   St. Petersburg State Pediatric Medical University, St. Petersburg, Russian Federation
Published: June 2023

Cytomegalovirus infection (CMVI) is the most common viral infection in childhood. Congenital CMVI is quite well studied, always causes alertness of neonatologists, and has a diverse clinical picture after the birth of a child. Certain difficulties in diagnosis are noted in children who have postnatal CMVI. As a rule, the infection is asymptomatic or slightly symptomatic and has no special serious clinical consequences, unlike congenital CMVI, which causes hearing loss and central nervous system damage. It is known that postnatal infection is dangerous for children with impaired immune system. This risk group consists of preterm infants, mainly with very low and extremely low body weight, and full-term infants with severe concomitant congenital and/or acquired pathology. The question of infecting ways for children with postnatal CMVI remains debatable. The article also discusses the various clinical manifestations of postnatal CMVI, which can occur according to the type of CMV-related sepsis-like syndrome, hepatitis, diarrhea, neutropenia. The article highlights the importance of clear laboratory diagnostic criteria during establishing the diagnosis. There are always a lot of questions from the doctor regarding the prescription of specific treatment in CMVI and prevention methods of postnatal CMVI in full-term infants. This article also presents clinical case of postnatal CMVI in full-term infants with combined pathology receiving treatment in the conditions of the Perinatal center of St. Petersburg State Pediatric Medical University. KEYWORDS: postnatal cytomegalovirus infection, cytomegalovirus hepatitis, hearing loss, diagnosis, treatment, breast milk, neonates. FOR CITATION: Panchenko A.S., Bem E.V., Chumakova G.N., Myznikova I.V. Сourse patterns of postnatal cytomegalovirus infection in full- term infants. Cases in clinical practice. Russian Journal of Woman and Child Health. 2023;6(2):206–214 (in Russ.). DOI: 10.32364/2618- 8430-2023-6-2-206-214.
Analysis of the efficacy of cytokine therapy in the treatment of chronic endometritis in women with reproductive losses
Authors:   Maternity Hospital No. 1, St. Petersburg, Russian Federation, Pluzhnikova T.A. , Alyabeva E.A. ,   Maternity Hospital No. 1, St. Petersburg, Russian Federation, Samarskaya I.V. ,   Maternity Hospital No. 1, St. Petersburg, Russian Federation
Published: June 2023

Aim: to evaluate the efficacy of using cytokine as an adjuvant therapeutic agent for the treatment of chronic endometritis (CE) in women with reproductive losses Patients and Methods: this prospective cohort study included 60 women with reproductive losses in the medical history who were examined at the preconception stage to identify potential causes of pregnancy losses and to prepare for future pregnancy. The diagnosis of moderate/ severe CE was established by histological and immunohistochemical methods in all patients. All patients received a two-stage treatment course. At the first stage, patients received standard treatment — antibacterial and enzymatic therapy. The study group patients (n=30, mean age 32.9±7.1 years) additionally received adjuvant cytokine therapy in rectal suppositories for 20 days, and the comparison group patients (n=30,mean age 33.5±7.5 years) — only standard therapy. One month after the end of treatment, a control examination of the endometrium was performed on days 21–23 of the ovarian cycle to assess histopathological findings in the endometrium and to measure immunohistochemical markers CD16, CD20, HLA-DR and CD138. Results: immunohistochemical tests showed that in the study group 16 (53.3%) patients had signs of moderate CR and 14 (46.7%) — severe CR, while in the comparison group 21 (70.0%) and 9 (30%) had moderate and severe CE, respectively. After the treatment these indicators in the study group amounted to 6 (20%) and 1 (10%), in the comparison group — 7 (23.3%) and 9 (30%). The combination therapy administered to both groups led to a statistically significant decrease in all evaluated (CD16+, CD20+, HLA-DR+, CD138+) indicators of local immunity. A decline in CD20 and CD138 markers after the treatment was more pronounced in the study group than in the comparison group (p=0.005 and p<0.001 respectively). Conclusion: topical cytokine therapy in patients with recurrent pregnancy loss has demonstrated its effectiveness for the correction of immune imbalance as it improves the morphological and functional characteristics of the endometrium. KEYWORDS: chronic endometritis, recurrent pregnancy loss, cytokines, cytokine therapy, preconception preparation. FOR CITATION: Pluzhnikova T.A., Alyabeva E.A., Samarskaya I.V. Analysis of the efficacy of cytokine therapy in the treatment of chronic endometritis in women with reproductive losses. Russian Journal of Woman and Child Health. 2023;6(2):88–94 (in Russ.). DOI: 10.32364/2618- 8430-2023-6-2-88-94.
A New Weave in the Pattern
Authors: Marrugo Andres
Published: June 2023

Editor-in-Chief Andres Marrugo discusses the role of Large Language Models, like ChatGPT, in academic publishing, highlighting some practical applications, potential pitfalls, and the ethical considerations required for their responsible use in academia.
Early marriage of Madurese women: A case study
Authors: Bawono Yudho
Published: June 2023

Early marriage in Indonesia has become an issue that has attracted the attention of various child and women’s monitoring institution since the proposed of revisions to the Marriage Law No. 1 of 1974 specifically in increasing the age limit for women’s marriages from 16 years to 18 years. The effort to submit a revision to the law itself are based on various problems caused by the existence of early marriage. However, in contrast to the conditions in Madura, early marriage does not always cause problems such as these findings. Madurese women who marry early can also achieve happiness and harmony in their marriage. This study aims to describe Madurese women who married early using a qualitative method with a case study approach. Research participants are Madurese women who are married under the age of 18, live in Madura and are willing to be involved in the research. Data collection using  interviews and field notes. The data analysis technique uses the Miles & Huberman interactive model by starting with data collection, data reduction, data display, verification or drawing conclusions. In checking the validity of the data uses triangulation and member check. Our findings reveal that early marriage was initially perceived by the participants as an unpleasant, but over time, early marriage has become a good thing for their lives.
KEDUDUKAN PENDIDIK DALAM PERSPEKTIF ISLAM MENURUT AKRIM DALAM BUKU ILMU PENDIDIKAN ISLAM
Authors: Zahrah Fatimatus , Arfa Ladamay Ode Mohamad Man
Published: June 2023

The background of this research is that educators do not only teach in that academic field, but are also required to have noble morals. But in the context of islamic eduaction, educators are known as murabbi, mu”allim, mudarris, and murshid. The position of an educator becomes a light in life in the world, especialli in the hereafter. In the context of islamic education, the position of an educator is very important. The type of reserch used is library researc and uses descriptive methods as data analysis techniques. The results of the study are that there are quite a lot of requirements to be fulfilled by educators indicating that the responsibilities and duties of educators are indeed heavy. However, it is pricesely because of that the he gets a very high position. The position of an educator as well as a parent is a position that he must do.
PENERAPAN PERPUSTAKAAN DIGITAL UNTUK OTOMATISASI PENGELOLAAN PERPUSTAKAAN KELURAHAN
Authors: Nurfadilla Nurfadilla , Budiantara Martinus
Published: June 2023

Abstract: Masalah yang dihadapi oleh mitra saat ini adalah pengelolaan buku dan proses pelayanan yang masih manual dan kurangnya kepengurusan perpustakaan. Untuk mengatasi masalah tersebut, perpustakaan membutuhkan sistem yang dapat mengumpulkan, mengolah, menyimpan, dan menyalurkan informasi. Oleh karena itu, perpustakaan harus memanfaatkan teknologi informasi seperti aplikasi sistem informasi beserta komputer untuk memenuhi kebutuhan tersebut. Sehingga solusi yang dapat diberikan oleh pengabdi untuk masalah tersebut adalah dengan melakukan pendampingan serta membantu pengelolaan perpustakaan dengan memanfaatkan platform perpustakaan digital seperti Slims. Metode pelaksanaan yang digunakan adalah dengan melakukan penerapan aplikasi serta pendampingan pengelolaan perpustakaan digital. Kesimpulan, kegiatan pengelolaan buku perpustakaan kelurahan wirogunan sudah terkomputerisasi dalam aplikasi perpustakaan digital. Pengurus perpustakaan kelurahan wirogunan juga memperoleh ilmu tentang pengelolaan perpustakan yang sesuai dengan standar serta perpustakaan digital ini sangat membantu pengurus perpustakaan kelurahan wirogunan dalam pelayanan dan pengelolaan buku yang lebih mudah dan efektif.
PENDAMPINGAN PEMANFAATAN TEKNOLOGI BERBASIS BLOG, SEBAGAI MEDIA PROMOSI DIGITAL UMKM
Authors: Surani Dewi , Septiyani Rini Dwi , Umalihayati Umalihayati
Published: June 2023

Kegiatan pendampingan pemanfaatan teknologi berbasis blog sebagai media promosi digital produk UMKM di wilayah kelurahan Dalung dipilih sebagai solusi peningkatan promosi karena blog merupakan teknologi yang mudah dibuat serta gampang dioperasikan teteapi mempunyai jangkau yang luas serta efektif sebagai media promosi karena tidak hanya berisikan tulisan tetapi juga visual seperti gambar. Pengandian diawali dengan analisis kebutuhan melalui observasi lapangan dan persiapan administrasi yang dibutuhkan, kemudian sosialisasi promosi digital dengan mengadakan seminar digital berbasis blog, serta menyiapkan media blog dan konten yang diambil secara langsung dari kegiatan usaha para UMKM yang terintegrasi dengan markeplace shopee, dan melakukan edukasi kepada aparat desa serta para pelaku UMKM menggunakan blog. Kemudian tahap terakhir melakukan melakukan supervisi untuk mengetahui sejauh mana media blog bisa mefasilitasi promosi digital. Keberadaan media blog diharapkan bisa diimanfaatkan berkelanjutan tidak hanya sebagai media digital marketing UMKM tetapi juga menjadi media informasi mengenai kekayaan budaya di lingkungan kelurahan Dalung Cipocok Jaya Serang Banten seperti pencak silat, debus dan wisata ziarah
Polygraph Examinations as Preventative Measure of Corruptive Behavior – A Case Study
Authors: Zaimova-Tsaneva Emelina , Vladimirova Velina , Todorov Todor , Genkov Daniel
Published: June 2023

The following publication presents brief case study of corruptive behavior of an employee of a private company for supplier of electricity. Interview and polygraph examination also was used. It also presents a short analysis of the corruption behavior problem as a psychological category. Methods for integrity assessment and the polygraph method are presented as instruments which have high validity and reliability. Besides the focus on psychodiagnosis of corruptive behavior, this publication pays attention to the need of incorporating preventive measures.
An Inquiry Into The Needs And Problems Of The Seventh-Day Adventist One-Parent Family
Authors:   ,   Andrews University, Staff Elwood
Published: June 2023

There has been much concern in recent years about the fate of the American family. This writer is focusing on the one-parent nuclear family. A further specification in the family under study is female-headed Seventh-day Adventist. This project then, is a multiple case study of maternal one- parent families. The small sample was chosen on a non-random basis with the object of typifying what might be found in a Seventh-day Adventist pastorate. The writer was successful in cooperation with the local pastor in obtaining a sample of thirteen Seventh-day Adventist maternal one- parent families where the parent has been widowed or divorced with at least one child living in the home. The survey procedure will be to conduct in-depth structured interviews. (The instrument is found in the Appendix.) The writer is not basing this explorative project on statistical means and averages or with a sufficient number of subjects to merit calling it a scientific study. Because of these above reasons, the results should not be generalized to a larger population. This project therefore, is not designed to be a technically scientific study but a tool for ministry. From these Seventh-day Adventist one-parent families the writer hoped to discover by means of these interviews their unique problems socially, emotionally, and physically; it was also the plan to have group sessions following the completion of the interviews. The duration of the sessions and how successful they were would depend on the writer's expertise and the willingness of the participants in this project to cooperate. It was hoped that the women would be encouraged to form groups which in turn would bring support, help, and information. It was hoped that their bond with the church would be strengthened through the special interest shown in them, not only by the writer and the group but by the local pastor. Specifically then, procedures in this project will be to research current literature on the subject of the one-parent family, to research what community services both on a local and national level might provide as resource assistance to this group, to discover what local pastors and/or their denominations are doing to meet their need, and finally, to explore pastoral possibilities in group sessions for these single parents. It was believed that there would be certain values in carrying out this project apart from the local parish. Those interviewed would be less likely to see it as prying and meddling when carried out as a seminary research project. Delicate subjects such as sex could be discussed more freely apart from local church connections. Prior experience of this nature would appear to offer some advantages to the writer and his future congregation. Specific personal objectives include: A greater knowledge of and competence in working for the Seventh-day Adventist one-parent family including the possibility of the development of a local church project and putting the findings into operation on a continuous basis.
An Evaluation Of The Concept And Function Of Mutual Ministry And Spiritual Gifts In The South Caribbean Conference
Authors:   ,   Andrews University, English Edwin
Published: June 2023

No abstract available.
Gotong Royong: A Study Of An Indonesian Concept And The Application Of Its Principles To The Seventh-Day Adventist Church In Indonesia
Authors:   ,   Andrews University, Hutauruk Jan
Published: June 2023

The purpose of this study is to investigate the possible relevance of the concept of gotong royong to church growth with special applications of its principles to the Seventh-day Adventist church (SDA) in Indonesia. (No Abstract)
The Prevalence of Internet Addiction and Its Relation With Demographic Factors Among the Students of Gonabad Universities
Authors:   Department of Psychology, Faculty of Literature and Human Sciences, Persian Gulf University, Bushehr, Iran., Safarzade Somayeh , Dehghani Yosef ,   Department of Psychology, Faculty of Literature and Human Sciences, Persian Gulf University, Bushehr, Iran.
Published: June 2023

Background: With the invention of the Internet and its widespread popularity, in addition to the many benefits, it was accompanied by many damages and problems. The biggest damage tousing this technology is addiction. Internet addiction can be a chronic, pervasive, recurring, and very damaging disorder. This study aimed to determine the prevalence of internet addiction and its relation with demographic factors among the students of Gonabad Universities in the academic year 2015-2016. Methods: The study design was cross-sectional. The sample of the study was all students of Azad and Payam Noor University of Gonabad. A total of 1182 students of Azad and Payam Noor University of Gonabad participated in the research process by simple random sampling. To collect data, the demographic questionnaire and Young’s Internet addiction scale was used. Data was analyzed using SPSS descriptive statistics software version 19, and the chi-squared test. Results: The prevalence rate of Internet addiction was 14.3%. The prevalence rate in male and female samples was 14.1% and 14.5%, respectively. A total of 33.9% of students in the sample were at risk of Internet addiction disorder. The results of chi-square test results showed no significant relationship between gender, marital status, the field of study, and Internet addiction (P>0.05). However, the results of the analysis indicated a significant relationship between age, place of residence, level of education, and type of university with the prevalence of Internet addiction (P<0.05). Conclusion: According to the high prevalence of Internet addiction among students, appropriate treatment interventions are required for Internet addiction students.
Developing a Based-on-play Cognitive-behavioral Educational Package and Determining Its Effectiveness in Improving the Language Disorders and Social Adjustment in Bilingual Children
Authors:   Department of Educational Psychology, Faculty of Psychology & Educational Sciences, Farhangian University, Bojnord, Iran., Rezaee Rezvan Shahrzad , Karashki Hossein ,   Department of Psychology, Faculty of Psychology & Educational Sciences, Ferdowsi University of Mashhad, Mashhad, Iran., Hajivosoogh Najmeh Sadat ,   Department of Psychology, Faculty of Medicine ,Gonabad University of Medical Sciences, Gonabad, Iran., Torabi Seyed Saeed ,   Department of educational psychology, Faculty of Psychology & Educational Sciences, Kharazmi University, Tehran, Iran.
Published: June 2023

Background: The present study was conducted to develop a game-based cognitive-behavioral educational package and determine its effectiveness in improving the receptive language disorders and social adjustment of bilingual children. Methods: The current study was applied objectively and in terms of the nature of the data, it was quasi-experimental with a pretest post-test design and follow-up with experimental, control, and pseudo-control groups. The statistical population of the research includes all bilingual children of Bojnord City, Iran who were studying in preschool centers in the academic year 2018-2019. A sample consisting of 60 male and female students was selected using convenience sampling and according to the inclusion and exclusion criteria, and they were randomly assigned to three experimental, control, and pseudo-control groups (each group with 20 people). In the pretest stages, the participants completed the Nikamer and Hamill language development test and the Dokhanchi social adjustment scale, and then during the intervention process of the experimental group, they received a game-based cognitive-behavioral training program for 12 sessions. The pseudo-control group received a program except for play therapy, and the control group received no intervention. After the end of the intervention, all three groups responded to both scales again in the post-test stages and were re-evaluated after two months. The data were analyzed using the analysis of variance test with repeated measurements and using SPSS software, versian 24. Results: The results showed that the game-based cognitive-behavioral intervention is significantly effective in improving the receptive language disorders and social adjustment of bilingual children compared to the control and quasi-control groups. Conclusion: It seems that game-based cognitive-behavioral interventions can play a significant role in improving the language skills and social adaptation of bilingual children.