bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Human Bone Marrow Mesenchymal Stem Cells on Burn Healing in Granulation Tissue Formation in Diabetic Rats
Authors: Revilla Gusti , Saputra Deddy , Nurhasanah Dini
Published: April 2023

Burns with diabetes mellitus can interfere with the wound-healing process. Mesenchymal stem cells have been studied to accelerate the healing of burns, one of which originates from the bone marrow. Objective: To determined the effect of human bone marrow mesenchymal stem cells (hBM-MSCs) on burn wound healing in granulation tissue formation in Diabetes Mellitus rats. Methods: This study was an experimental study with a post-test-only control group design, using 30 rats divided into two groups, the control group Phosphate Buffer Saline (PBS) and the treatment group (hBM-MSCs). Mice were induced by alloxan to cause hyperglycemia. Burns are made using a heated plate. Tissue collection was carried out after the termination of the experimental animals on the 3rd, 7th and 14th days and then histological preparations were made to assess the formation of granulation tissue. Data were analyzed using the two-way ANOVA test. Results: There was an increase in the number of macrophages, fibroblasts and new blood vessels after being given hBM-MSCs. On day 14 neutrophils and lymphocytes on day 3, there was no increase. Statistical analysis showed a significant increase in lymphocytes, macrophages, fibroblasts and new blood vessels. Conclusion: Human bone marrow mesenchymal stem cells can increase the formation of granulation tissue by increasing the number of macrophages, fibroblasts and new blood vessels in diabetic rats.Keywords: burn wound,  diabetic rat, human bone marrow mesenchymal stem cells, granulation tissue
Pengaruh Art Therapy terhadap Kualitas Hidup Anak Kanker yang Menjalani Kemoterapi
Authors: Hasni Hidayatul , Andika Mira , Syahid Armein
Published: April 2023

Continuous chemotherapy causes side effects in children, one of which affects the quality of life of children. The quality of life of children with cancer can be improved by providing complementary and alternative therapies, one of which is art therapy. Objective: To determine art therapy's effect on the quality of life of cancer children undergoing chemotherapy. Methods: The design of this study was a quasi-experimental one-group pre-test post-test on 30 children with cancer who underwent chemotherapy. The art therapy in this study was coloring activities. Quality of life assessed using PedsQoL instruments (Pediatric‘s Quality of Life) Generic 4.0. Data analysis used the Mann-Whitney test. Results: The average age of children with cancer was ten, and more than half (53.3%) were male. Most of them were diagnosed with Acute Leukemia Limfoblastic and more than half (73.3%) were diagnosed more than six months. There was a difference in the quality of life of children with cancer before and after being given art therapy with a p-value = 0.000 (<0.05). Art therapy affected the quality of life of cancer children undergoing chemotherapy with a p-value of 0.000 (<0.05). Conclusion: Art therapy can improve the quality of life of cancer children undergoing chemotherapy. Keywords:  art therapy, chemotherapy, children with cancer, quality of life
Obiekty sztuki sakralnej we francuskich kolekcjach prywatnych w XIX wieku – wybrane przykłady
Authors: Białonowska Magdalena
Published: April 2023

Artykuł dotyczy problematyki funkcjonowania obiektów sztuki sakralnej w kolekcjach powstających we Francji w 1. połowie XIX wieku. W kontekście wandalizmu Wielkiej Rewolucji Francuskiej zrodził się ruch teoretyków, którzy sprzeciwiali się destrukcji i opowiadali za ochroną zabytków jako pomników historii Francji. Ruch ten zainspirował wśród kolekcjonerów zainteresowanie sztuką sakralną, głównie średniowieczną. W artykule została przywołana postać Alexandre Lenoira (1761–1839), następnie kolekcje średniowiecznej sztuki sakralnej stworzone przez: Alexandra Du Sommerarda (1779-1842); Pierra Révoila (1776–1842); Alexandre’a Sauvageota (1781-1860); Louisa Fidela Debruge-Dumenila (1788–1838) oraz Jeana-Baptiste’a (1792–1871) i Louis (1827-1888) Carranda. Analiza zawartości i historii tychże kolekcji pozwoliła wysnuć wnioski na temat zmieniających się pobudek, dla których kolekcjonerzy 1. połowy XIX wieku gromadzili obiekty sztuki sakralnej, od potrzeby ratowania zabytków sztuki francuskiej po traktowanie ich jako materiał badawczy.
The Church and the Liturgy in the Contemporary World
Authors: Jeziorski Sławomir
Published: April 2023

Kościół i liturgia we współczesnym świecie
 Pytanie o kształt celebracji liturgicznej często powraca w dyskusji pastoralnej. Odpowiedzi, jednak, które prowokuje nie zawsze wynikają z refleksji, która uwzględniałaby zarówno kontekst kulturowy jak i wymiar teologiczny liturgii.
Niniejszy artykuł jest próbą takiego poszukiwania odpowiedzi na pytanie o liturgię we współczesnym świecie, które uwzględniałoby zarówno aktualną kulturę i właściwą mu mentalność, nie pomijając zarazem tego co istotne dla celebrowanego misterium.
Wobec tego, w artykule zostaje zarysowana charakterystyka współczesnej epoki i jej wpływ na myślenie kościelne. Dopiero na tak zarysowanym tle przedstawione jest to co wydaje się być dzisiaj nieodzowne dla celebracji, a co wynika z samej jej treści teologicznej: bezinteresowność, wolność, piękno i witalność.
Słowo podstawowym narzędziem gregoriańskiej techniki kompozytorskiej w adaptacji wzorców modalnych do nowych tekstów
Authors: Ferfoglia Susi
Published: April 2023

W artykule Autorka pyta się jak powstały melodie gregoriańskie? W jaki sposób zostały one zapisane? Czy zapis może być narzędziem do głębszego zrozumienia tekstu? Autorka wchodzi w ten sposób w tajniki gregoriańskiej techniki kompozytorskiej; polega ona przede wszystkim na wykorzystywaniu tych samych formuł albo nawet całych melodii do różnych tekstów, w czym wyraźnie widać, że kompozytor gregoriański „myślał słowem”. Każdy nowy tekst zawiera inny rytm werbalny, wynikający z natury słów, a to nadaje tej samej melodii nowy sens i nowe znaczenie w nowym kontekście słownym. Aby przekonać się o prawdziwości tego stwierdzenia i wyrafinowaniu zabiegu kompozytorskiego nie wystarczy spojrzeć tylko notację watykańską; trzeba sięgnąć do notacji adiastematycznej, która przekazuje rytm przebiegu melodycznego. Porównanie ze sobą tych samych melodii w różnych kontekstach słownych z różnym rytmem pokazuje nam, że ta sama melodia staje się dla kompozytora „pretekstem” do wyrażenia czegoś więcej. W artykule zostały przeanalizowane trzy melodie (graduały) bazujące na wzorcu modalnym piątego modusu, czyli tritusa plagalnego (Christus factus est, Exiit sermo, Ecce sacerdos magnus), Na ich przykładzie Autorka pokazuje, w jaki sposób wzorzec modalny tritusa plagalnego został zaadaptowany do nowego tekstu.
Inspiracje kultem maryjnym w twórczości Andrzeja Panufnika
Authors: Fabiańska-Jelińska Ewa , Nowak Weronika
Published: April 2023

Celem artykułu jest przedstawienie twórczości muzycznej Andrzeja Panufnika inspirowanej kultem maryjnym. Spuścizna kompozytora związana z postacią Matki Bożej (zwłaszcza zaś takie utwory, jak: Modlitwa do Matki Boskiej Skępskiej, Pieśń do Marii Panny) rozważona zostaje z perspektywy biografii twórcy oraz innych jego kompozycji o tematyce religijnej (takich, jak m.in. Koncert fagotowy, Sinfonia votiva). Ponadto w interpretacji wybranej twórczości Panufnika uwzględniony został kontekst kultu maryjnego w Polsce, ukazany z perspektywy historycznej, a także z perspektywy tradycji lokalnej.
Sperm DNA integrity and reproductive toxicity of lead nitrate in adult male mice
Authors:   Universidad Nacional Mayor de San Marcos, Gonzáles Daga José M. , Vásquez Cavero Jonathan H. , López Sam Rosmary Y. , Pino Velásquez Pilar Valeria , Pino Gaviño José Luis , Shiga Oshige Betty E.
Published: April 2023

Introduction: Lead toxicity has been linked to different diseases in humans and several evidences suggest a strong relationship with the observed damage on reproductive function in humans and rodents. Methods: we provide to mice a single dose of lead nitrate (LN) of 50mg/kg body weight. Mice were euthanized seven days post-injection with the aim of evaluating sperm to come out from the seminiferous tubules and are in transit through the epididymis. Also the TUNEL test was done to evaluate the sperm DNA fragmentation. Results: The decrease in body weight in mice treated with LN (p <0.05), suggest a toxic systemic effect. However, we didn´t find an effect on the reproductive system because the weights of the testes, epididymis, prostate and seminal vesicles were not altered (p>0.05), in the same way physiological values such as sperm concentration and motility didn´t decrease with the treatment (p> 0.05). Transit and sperm maturation in the epididymis would not be affected by the LN, and because we did not observe increased sperm DNA fragmentation in the treated group (p>0.05), sperm protamination would be fulfilling its protective role on murine genetic material avoiding genotoxic damage by LN. Conclusion: The intraperitoneal administration of 50mg/kg/pc of lead nitrate (LN) for seven days does not cause systemic toxicity or effect on spermatogenesis in mice.
Limitaciones al ejecutar un proyecto de desarrollo en una comunidad rural del centro de México
Authors: Herrera-Cárdenas Jorge , Castillo-Sanguino Narciso , Delgado-Reyes Sergio , Silva-Gómez Sonia
Published: April 2023

Con la finalidad de rescatar los aspectos históricos del cooperativismo en la mixteca poblana, se realizó una investigación cualitativa mediante un instrumento de entrevista semiestructurada que se aplicó a los familiares de los ejidatarios fundadores de una granja porcina constituida como cooperativa en la comunidad de Santa Cruz Agua Escondida. Las preguntas fueron estructuradas en ocho rubros: integración de la organización, política organizacional, actividades realizadas, control de calidad, sistemas de financiamiento, identidad organizacional, procesos de formación y declive de la organización.  Los resultados muestran que el establecimiento de la granja se dio a través de un crédito del Banco del Crédito Rural del Centro Sur, la granja representó una importante fuente de empleo, con el cierre de las actividades hubo un incremento en diversos problemas sociales como inseguridad y drogadicción, la cooperativa contaba con asesoría técnica esporádica, pero no en temas de índole financiero y el declive de la granja se dio cuando la mayoría de los miembros salieron de la cooperativa pues de 45 ejidatarios fundadores solo terminaron 13 lo que derivó en complicaciones económicas y en el cierre definitivo. Se concluye que, a pesar de los múltiples esfuerzos por parte de las autoridades federales de impulsar el desarrollo del campo, la falta de asistencia técnica y financiera ha imposibilitado la continuidad de proyectos como el que se aborda en este trabajo.
Recital Vector Dot Operations for Chemistry Students
Authors: Chen Jixin
Published: April 2023

I have been teaching physical chemistry to undergraduate students for several years now. I have observed that my interpretation of vector-matrix calculations and complex calculations has not been well received by the chemistry students. The traditional vector notation of adding an arrow on top of a variable and the matrix format work for students with vector and matrix-associated training backgrounds but are not well received by the students who have not seen it before.1 We have been using vector square calculations in these classes in many places. Thus, there is a need to introduce vector calculations, especially square vector calculations to these students. I have recommended the students watch outstanding YouTube channels such as 3Blue1Brown that visualize vector calculations. I am proposing here to introduce a form more like linear algebra that is more familiar to the students and focuses on the DOT operations of the vectors to these undergraduate students. Linearized vector notations have been widely used in almost all computer coding languages and have been proven to be efficient by many coders.
Elucidating the reaction pathway of glucose electrooxidation to its valuable products: the Influence of mass transport and electrode potential on the product distribution
Authors: Arenz Matthias , Schlegel Nicolas , Bagger Alexander , Rossmeisl Jan
Published: April 2023

Converting glucose electrochemically to its valuable derivatives, gluconic and glucaric acid, is a promising process for the utilization of renewable carbon sources. Understanding the reaction pathway to form glucaric acid from glucose is key in performing the process efficiently. In this study we investigate the influence of mass transport as well as electrode potential on the product distribution in glucose, gluconic acid and glucuronic acid oxidation on a gold disk in an RDE-setup. We find glucose and glucuronic acid to be easily oxidized, while the oxidation of gluconic acid is kinetically limited. Combining DFT calculations and the experimental results, we show that on gold, the oxidation of aldehyde groups proceeds readily while the oxidation of hydroxyl groups is challenging and occurs indiscriminately on C-atoms in glucose and its derivatives. Additionally, the DFT calculation present a reaction pathway which can explain the absence of glucuronic acid in the conducted experiments.
Sublimation Thermodynamics of 5,10,15,20–Tetraphenyl-21-X, 23-Y-Heteroporphyrins (X=O or S; Y= N or S). The Molecular structure of 5,10,15,20-Tetraphenyl-21-thiaporphyrin
Authors: Kuzmin Ilya , Shlykov Sergey , Krasnov Alexander , Pukhovskaya Svetlana , Syrbu Sergey , Ivanova Yulia
Published: April 2023

Sublimation enthalpies of 10,15,20–tetraphenyl-21-oxa- (I), 5,10,15,20-tetraphenyl-21-thia- (II) and 5,10,15,20-tetraphenyl-21,23-dithia- (III) porphyrines were measured by Knudsen effusion mass spectrometry: ΔHsubl.(T) = 209±2 (561 K), 224±2 (552 K) and 219±2 (577 K) kJ/mol, respectively. A structure of a free molecule of II was studied by quantum chemistry and gas-phase electron diffraction. The molecular structures of the dimeric associates of I-III were tested by quantum chemical calculations.
A Wearable Electrochemical Biosensor for Lactate Monitoring in Sweat
Authors: Ali Mohammed Hassan , Mahmoud Ahmed Tariq , Abdullah Karim Hisham
Published: April 2023

This study aimed to optimize the inkjet printing process for the fabrication of rGO- based lactate biosensors. The ink used for printing possessed proper fluidic properties, and the droplets were connected on the film by repeated printing process. The ink also contained ethyl cellulose, which reduced the coffee ring effect and resulted in a uniform film of rGO. The optimal density of Anti-L on the surface of the sensor was found to be 200 mM, and the incubation time for lactate samples was optimized to 60 minutes. The device showed linear responses from 100 to 500 μM with a high sensitivity of about 0.5 per 100 μM lactate and a low detection limit at 23 μM at S/N=3. This study demonstrates that optimized inkjet printing can be used to fabricate highly sensitive lactate biosensors for various applications.
Glycolipids from the gut symbiont Bacteroides fragilis are agonists for natural killer T cells and induce their regulatory differentiation
Authors: Cameron Garth , Nguyen Tram , Cuila Marcin , Williams Spencer , Godfrey Dale
Published: April 2023

Natural Killer T (NKT) cells are a lipid-antigen reactive, CD1d-restricted T cell subset with diverse functional properties that contribute to inflammatory and regulatory immune responses. The most studied lipid antigen target for these cells is alpha-galactosylceramide (GC). The commensal organism Bacteroides fragilis (B. fragilis) produces several forms of GC, but conflicting information exists about the influence of these lipids on NKT cells. Herein, we report the total synthesis of a major form of alpha-GC from B. fragilis (Bf alpha-GC), and several analogues thereof. We confirm the T cell receptor (TCR)-mediated recognition of these glycolipids by mouse and human NKT cells. Despite the natural structure of Bf alpha-GC containing lipid branching that limits potency, we demonstrate that Bf alpha-GC drives mouse NKT cells to proliferate and differentiate into producers of the immunoregulatory cytokine, interleukin-10 (IL-10). These Bf alpha-GC-experienced NKT cells display regulatory function by inhibiting the expansion of naïve NKT cells upon subsequent exposure to this antigen. Moreover, this regulatory activity impacts more than just NKT cells, as demonstrated by the NKT cell-mediated inhibition of antigen-stimulated mucosal-associated invariant T (MAIT) cells. These findings reveal that B. fragilis-derived NKT cell agonists may have broad immunoregulatory activity, providing insight into the mechanisms influencing immune tolerance to commensal bacteria and highlighting a potential means to manipulate NKT cell function for therapeutic benefit.
Stages of Stick-Slip Preparation on Precut Faults in Laboratory Models, and Verification of the Stages in Nature
Authors:   Institute of the Earth's Crust, Siberian Branch of RAS, Bornyakov S.A. , Guo Yanshuang ,   Institute of Geology, China Earthquake Administration, Panteleev I.A. ,   Institute of Continuous Media Mechanics, Ural Branch of the Russian Academy of Sciences, Zhuo Yan-Qun ,   Institute of Geology, China Earthquake Administration, Dobrynina A. A. ,   Institute of the Earth's Crust SB RAS, Sankov V. A. ,   Institute of the Earth's Crust SB RAS,   Irkutsk State University, Salko D. V. ,   Institute of the Earth's Crust SB RAS, Shagun A. N. ,   Institute of the Earth's Crust SB RAS, Karimova A. A. ,   Institute of the Earth's Crust SB RAS,   Irkutsk State University
Published: April 2023

This study is focused on analog modeling of the stick-slip process along an existing large fault in an elastic-viscoplastic model subjected to loading at a constant strain rate. Based on our model results and data from (Ma et al., 2012, 2014), we distinguish stable, meta-stable, and meta-instable stages of the stick-slip process (the latter includes the early and late sub-stages). Our experiments show that the fault is periodically reactivated by segmentation. We analysed this mechanism from one fault reactivation to another, and identified regressive and progressive trends of segmentation. The regressive segmentation takes place during the stable and meta-stable stages of the stick-slip process. Under regressive segmentation the number of active segments and their lengths are reduced. The progressive segmentation is initiated at the early meta-instable sub-stage of the stick-slip process. Its activity is desplayed by an increase in the number of active segments to a certain critical density, while their pattern becomes more chaotic. In the late sub-stage, number of segments decreases as they rapidly grow and join with each other to form larger active segments, up to full reactivation of the entire fault. For comparison with the model results, we interpret rock deformation monitoring records before the Bystroe earthquake. Our analysis confirms specific features of the anomalous rock deformation that are similar to the strain features observed along the model fault during the meta-instable stage. There are evidence to suggest that meta-instability of a fault is a potential candidate to short-term precursor of earthquakes.
Equity throughout the life course and the evolving role of the Pan American Health Organization
Authors: Butrón Riveros Betzabé , Rice Marilyn , Toscano Cristiana , Campos Esteban Maria Pilar , Duran Pablo , Eijkemans Gerry , Serruya Suzanne , Vega Enrique , Velandia-González Martha , de Francisco Luis Andres
Published: April 2023

The objective of this article is to summarize the evolution of the regional commitments of the Pan American Health Organization (PAHO) on health promotion and strategies to improve the health and well-being of women, children, adolescents, and older persons. PAHO regional strategies approved by Member States in the last 20 years are used as the main source of information. The article presents the challenges of making health promotion a public health strategy widely applied in the Region of the Americas and the efforts to renew Member States’ collective actions. The article also describes current PAHO efforts to include the positive aspects of health (i.e., well-being, optimal development, and functional ability) and the life course approach as opportunities to advance equity. The article reflects on immunization as a public good and the urgency to address the current challenges as a core element of the regional efforts to transform health systems after more than two years of the COVID-19 pandemic.
Cien años de la Revista Panamericana de Salud Pública: visualización de sus contenidos
Authors: Di Fabio José Luis , Delgado García Beatriz
Published: April 2023

Objetivos.

Explorar la alineación del contenido de los artículos publicados por la Revista Panamericana de Salud Pública durante sus 100 años de existencia, con los temas sanitarios claves de la Organización Panamericana de la Salud (OPS).

Métodos.

Se llevó a cabo un análisis bibliométrico con visualización de sus resultados. Se recuperó la información sobre los artículos publicados en la Revista a partir del Repositorio Institucional para Intercambio de Información (IRIS) de la OPS para los primeros 75 años y de Scopus para los últimos 25 años hasta febrero del 2022; para establecer los temas claves de la OPS se usaron referencias a documentos de los Cuerpos Directivos y declaraciones de los directores.

Resultados.

Se obtuvieron inicialmente 12 573 publicaciones y se consideraron para el análisis 9 289 para el período 1922 a 1996 y 3 208 para el período 1997 a 2022. Para el análisis bibliométrico de la información de Scopus se tuvieron en cuenta indicadores como los autores y su procedencia, el idioma de las publicaciones, y el número y la procedencia de las citas. Para las visualizaciones, se dividieron las publicaciones en cinco períodos a fin de que estos coincidieran con los períodos establecidos para el análisis de los temas prioritarios de la OPS. Se realizaron mapas de coocurrencia de palabras claves para observar la evolución de los temas de las publicaciones y relacionarlos con los enfoques de la salud pública en cada período.

Conclusión.

Las temáticas publicadas en la Revista Panamericana de Salud Pública y sus boletines precursores reflejan la historia de la salud pública regional y su evolución a lo largo del tiempo, así como los temas sanitarios claves de la Organización Panamericana de la Salud.
“3 Degrees and 8 Combinations” Teaching Mode of Anti-Seismic Design of Building Structures
Authors: Li Huina
Published: April 2023

Earthquakes pose a significant threat to people’s property and personal safety. Improving the teaching of civil engineering and building structure anti-seismic design courses can enable students to do a good job in anti-seismic design in the future and effectively reduce the damage on buildings caused by earthquakes. In this paper, we analyzed the basic characteristics of a course in civil engineering major, which is Anti-Seismic Design of Building Structures, and the shortcomings of traditional teaching. It is proposed that the 3-degrees and 8-combinations teaching mode of anti-seismic design of building structures can effectively improve students’ autonomy and enthusiasm in learning, helps to cultivate professional ethics among students, and improve their ability to apply what they have learned.
Design Strategy of Collector-Distributor Lanes in Urban Interchanges
Authors: Yang Yao
Published: April 2023

Based on the functions and characteristics of the interchange collector-distributor lanes, with Harbin as an example, it is proposed in this paper  that the local characteristics and traffic flow characteristics should be considered in the design of the interchange collector-distributor lanes, which includes the analysis of function, location, and many other aspects, in hopes to provide reference for the design of collector-distributor lanes in other regions of our country.
Analysis of Highway Roadbed Performance Evaluation Technology
Authors: Liu Shuyan , Zhou Yunyong , Tu Ke , Wu Daqing , Ye Yingying
Published: April 2023

With the continuous development of China, the requirements for road construction are also increasing. Among them, strengthening the performance of roadbed test can effectively improve road construction. Besides, it is also crucial to perform suitable tests in a timely manner. Therefore, highway inspection technology should be improved for the continuous development of highway construction, which will be explained in this paper, in hopes of improving the construction of highway in China.
Research Progress and Prospect of Tourism Carbon Emissions and Its Uncertainty Analysis Under the Goal of Low-Carbon Scenic Spots
Authors: Wang Aihong , Lyu Qiguang
Published: April 2023

Under the dual carbon goal, China Certified Emissions Reductions (CCER) and the national carbon market have become important means of emission reduction and control. The tourism industry is a strategic pillar industry of China’s national economy, and scenic spots are the main sites of tourism activities. Research on carbon emissions in scenic spots is of great significance for the construction of low-carbon scenic spots and the realization of the dual carbon goal. In this paper, the research on carbon emissions in tourism is reviewed, the current research progress is discussed, and further prospects are made. The research on tourism carbon emissions in China has a good foundation and achieved certain results. However, there are few studies on micro-scales such as scenic spots. The statistical data caliber and measurement methods of carbon emissions are not uniform, and there is a general lack of uncertainty analysis. Future research should focus on building a multi-spatial dimension research system, unifying the statistical caliber and measurement methods of carbon emission data, increasing uncertainty analysis, and ensuring the robustness of research results.
CA‘FER-İ TAYYÂR’IN REHBER-İ GÜLİSTÂN’DA ARUZ İMLASINA DAİR TESPİTLERİ VE TELAFFUZ TEKLİFLERİ
Authors: ŞENLİK Osman
Published: April 2023

Sa‘dî Şirâzî’nin (öl. 691/1292) Gülistân’ı üzerine 20. yüzyıla kadar otuzu aşkın Türkçe şerh yazılmıştır. 19. yüzyılda yaşamış Farsça muallimi Ca‘fer-i Tayyâr’ın yazdığı Rehber-i Gülistân şerhi, son dönem şerhlerinden olup pek tanınmamıştır. Tayyâr, bu eserinde Gülistân’ı kelime kelime tercüme etmiş, Arapça ve Farsça kelimelerin aldıkları harf ve ekleri gramer bakımından açıklamış ve manalarını vermiştir. Tayyâr, şerh içerisinde yeri geldikçe beyitlerin aruza ve kafiyeye uygun okunması için uyarılarda bulunmuştur. Bu çalışmada Gülistân’daki manzum metinlerin aruz imlasına uygun telaffuzları için Tayyâr’ın yaptığı teklifler tespit edilecektir.
İlkokul Sınıf Öğretmenlerinin Dördüncü Sınıf Sosyal Bilgiler Dersindeki Liderlik Kavramına İlişkin Algılarının ve Oluşturdukları Etkinliklerin İncelenmesi
Authors: ÖZTEPE Demet , ÜTKÜR GÜLLÜHAN Nur
Published: April 2023

Bu araştırmanın amacı, sınıf öğretmenlerinin dördüncü sınıf sosyal bilgiler dersindeki liderlik kavramına ilişkin algılarının ve oluşturdukları etkinliklerin incelenmesine dayanmaktadır. Araştırmada nitel araştırma yöntemi kullanılmış olup, çalışma grubunu 2022-2023 eğitim-öğretim yılında İstanbul ili Beyoğlu ilçesindeki 12 sınıf öğretmeni oluşturmaktadır. Veri toplama aracı olarak kişisel bilgi formu ve yarı yapılandırılmış görüşme kullanılmıştır. Elde edilen verilerin analizinde, içerik ve betimsel analiz kullanılarak, oluşturulan kod ve temalar alan uzmanı tarafından değerlendirilmiş olup, aralarında tutarlılık sağlanmıştır. Bulguların analizleri sonucunda; Sınıf öğretmenleri liderlik kavramının daha çok “insanları yönlendirme becerisi” gibi iletişim boyutuna vurgu yaparken, liderlik konusunun önemini “sorumluluk alma” olarak belirtmişlerdir. Sınıf öğretmenleri liderlik kavramının öğretiminde etkinlik kullanımının “kalıcı öğrenme” ve “aktif katılımı” sağladığını belirtirken, oluşturdukları etkinliklerde, daha çok “Atatürk konulu” içerikleri seçtikleri, “drama” kullanımına öncelik verdikleri ve materyal olarak “lider resimlerini” sıkça kullandıklarını belirtmişlerdir.
Historical evolution of taxonomic classification of hemp
Authors: Alonso-Esteban José Ignacio , Sánchez-Mata María de Cortes , Torija-Isasa Esperanza
Published: April 2023

Hemp (Cannabis sativa L.) is a plant which is widely spread throughout the world. It is one of the oldest sources of textile fibres, but it has also stood out for its medicinal and food uses. The domestication process carried out by humans, focused on obtaining different products, has brought with it a biological evolution from the anatomical, morphological, physiological and chemical points of view. Furthermore, hybridization has also largely conditioned the evolutionary process of hemp. This has made the taxonomic classification of hemp extremely difficult, which has been highly controversial. During the Early Modern Period, some authors considered that there were different species, while others affirmed that all the specimens corresponded to a single species. The chemical characterization of cannabinoids, the most characteristic compounds of the secondary metabolism of hemp, took place in the 20th century. Because of this, the content of some of these compounds was included as a classification criterion. However, the discrepancies between the authors on whether the Cannabis genus was monotypic or polytypic were not resolved. In the 21st century, the taxonomic classification of hemp continues under study because of the absence of consensus. El cáñamo (Cannabis sativa L.) es una planta ampliamente extendida por el mundo. Se trata de una de las fuentes más antiguas de fibras textiles, pero también ha destacado por sus usos medicinales y alimentarios. El proceso de domesticación llevado a cabo por el ser humano, centrado en la obtención de productos diferentes, ha llevado consigo una evolución biológica de planta desde los puntos de vista anatómico, morfológico, fisiológico y químico. Además, la hibridación también ha condicionado en gran medida el proceso de evolución del cáñamo, lo que ha dificultado enormemente su clasificación taxonómica, que ha sido muy controvertida. Durante la Edad Moderna, algunos autores consideraban que había diferentes especies, mientras que otros afirmaban que todos los especímenes se correspondían con una única especie. En el siglo XX tuvo lugar la caracterización química de los cannabinoides, los compuestos más característicos del metabolismo secundario del cáñamo, y esto permitió incluir como criterio de clasificación el contenido de algunos de ellos. Sin embargo, seguía habiendo discrepancias entre los autores sobre si el género Cannabis era monotípico o politípico. En el siglo XXI, la clasificación taxonómica del cáñamo continúa siendo objeto de estudio ante la falta de consenso
History of the ichthyological knowledge of the Galician sea
Authors: Bañón Rafae , Maño Toño
Published: April 2023

This paper analyses the historical knowledge of marine ichthyology in Galicia through an interdisciplinary approach that integrates information from diverse sources of documented information. The history of ichthyology has evolved with the way humans relate to the natural world. The study of activities related to marine fish as an important source of food has been the main source of knowledge throughout history. From the 18th century onwards, with the invention of the binomial nomenclature, scientific interest and an acceleration of ichthyological knowledge arose. Since the end of the 20th century, technological progress, both exploratory and analytical (molecular taxonomy), has led to a greater knowledge of the deep ichthyofaunal and the application of integrative taxonomy, with the discovery of new taxonomic relationships. Numerous national and Galician ichthyologists have contributed to this knowledge, with an important contribution from foreign researchers, especially from France. En el presente trabajo se analiza la evolución del conocimiento ictiológico del mar de Galicia a lo largo de la historia mediante un enfoque interdisciplinario que integra información documentada procedente de fuentes de diversa naturaleza. El conocimiento ictiológico ha ido evolucionando con el modo de relacionarse del ser humano con el mundo natural. El estudio de las actividades relacionadas con los peces marinos como recurso alimentario y económico constituye la principal fuente de conocimiento a lo largo de la historia. A partir del siglo XVIII, la invención de la nomenclatura binomial da un nuevo impulso al interés científico, que trae consigo una aceleración del conocimiento ictiológico. Desde finales del siglo XX los progresos tecnológicos, tanto exploratorios como analíticos (taxonomía molecular), han permitido un mayor conocimiento de la ictiofauna de zonas profundas y la aplicación de la taxonomía integrativa, con el descubrimiento de nuevas relaciones taxonómicas. Numerosos ictiólogos nacionales y gallegos han contribuido a este conocimiento, con una importante aportación de los investigadores extranjeros, sobre todo franceses.
George Evelyn Hutchinson’s legacy in modern ecology and limnology
Authors: Sánchez-Hernández Javier
Published: April 2023

George Evelyn Hutchinson is recognised as one of the best limnologists and ecologists of the 20th century, whose contributions have been key for the development of modern ecology and limnology. His most important contributions nclude, concepts, theories and classifications currently used such as, for example, the ecological niche concept, Hutchinson’s paradox and lake classifications. Hutchinson redefined the ecological niche concept based on previous ideas of Grinnell and Elton, suggesting that it should be considered as a hypervolume in the environmental space caused by the ultidimensional response of variables that determine the stability of populations. This new perception of the ecological niche has been fundamental for the development of other investigations in different fields of biology, in particular in ecology, evolution, and biogeography. Furthermore, Hutchinson’s treatise on limnology is considered as the most extensive compilation of limnology. Hutchinson aimed to answer why several species of phytoplankton that compete for the same resources can coexist in an aquatic ecosystem which is usually nutrient deficient (known as the Hutchinson’s paradox). The scientific advances promoted by Hutchinson have inspired many generations of biologists. George Evelyn Hutchinson es reconocido como uno de los mejores limnólogos y ecólogos del siglo XX, cuyas aportaciones han sido cruciales para el desarrollo de la ecología y limnología moderna. Sus más importantes contribuciones incluyen conceptos, teorías y clasificaciones vigentes en la actualidad como, por ejemplo, el concepto de nicho ecológico, la paradoja de Hutchinson y las clasificaciones de lagos. A partir de las ideas de Grinnell y Elton, Hutchinson sugirió que el concepto de nicho ecológico debía considerarse como un hipervolumen en el espacio ambiental originado por la respuesta multidimensional de las variables que determinan la estabilidad de las poblaciones. Esta nueva percepción del nicho ecológico ha sido fundamental para el desarrollo de otras investigaciones en diferentes campos de la biología, particularmente en la ecología, la evolución y la biogeografía. Por otro lado, el tratado de limnología realizado por Hutchinson es considerado como la recopilación más extensa de la limnología. Hutchinson intentó dar respuesta a por qué varias especies del fitoplancton que compiten por los mismos recursos pueden coexistir en un ecosistema acuático que por naturaleza suele ser deficiente en nutrientes (conocido como la paradoja de Hutchinson). Los avances científicos promovidos por Hutchinson han servido de fuente de inspiración a muchas generaciones de biólogos.
Twin births in Spain and Andalusia (1996–2020)
Authors: Beteta-Avio Ramón
Published: April 2023

Twin births constitute an aspect of the birth rate of great interest because their frequencies characterize the populations. The objective is to present and compare the results of the variables studied: frequencies and rates, age at childbearing, secondary proportion by sex and seasonality. In addition, a section is dedicated to assisted reproduction techniques, as this is the factor that has most affected them. The data used come from the websites of the National Institute of Statistics, the Institute of Statistics and Cartography of Andalusia and the Spanish Fertility Society. The Weinberg method is used to differentiate between dizygotic and monozygotic births, and Henry’s seasonal coefficient is used to find their distribution by month. The frequencies report a maximum in Spain in 2014, and in 2017 in Andalusia. In both populations, twin births decrease in women younger than 34 years and increase in women older than 35 years. They report a sex ratio with great equalit\y between sexes, and a seasonality with maximum coefficients in autumn and minimum in spring. Los partos gemelares constituyen un aspecto de la natalidad de gran interés porque sus frecuencias caracterizan a las poblaciones. El objetivo es realizar una exposición y comparación de los resultados de las variables trabajadas: frecuencias y tasas, edad de maternidad, proporción secundaria por sexos y estacionalidad, además, se dedica un apartado a las técnicas de reproducción asistida al ser el factor que más las ha afectado. Los datos utilizados proceden de las webs del Instituto Nacional de Estadística, el Instituto de Estadística y Cartografía de Andalucía y de la Sociedad Española de Fertilidad. Se emplea el método de Weinberg para diferenciar los partos dicigóticos \ monocigóticos, y el coeficiente estacional de Henry para hallar su distribución por meses. Las frecuencias reportan un máximo en España en el año 2014, y en el 2017 en Andalucía. En ambas poblaciones descienden los partos gemelares en las mujeres menores de 34 años y aumentan en las mayores de 35. Reportan una “sex ratio” con gran igualdad entre sexos, y una estacionalidad con coeficientes máximos en el otoño \ mínimos en primavera.
The persecution of the wolf (Canis lupus Linnaeus, 1758) in Extremadura (Spain) by means of poisons (16th-19th centuries): a regional-scale analysis of historical records
Authors: Ferrero-García Juan J. , Torres-Vila Luis M.
Published: April 2023

The wolf Canis lupus and other carnivore were fiercely persecuted in the past because of the damage caused to livestock and game. Among the methods used for their control were poisons. Here we study the poison typology used in Extremadura (Spain) for four centuries (16th19th), their prevalence and the municipalities where they were applied. For this, we review the municipal Agreement Books of more than 200 municipalities of Extremadura and its surroundings. In the studied period, the use of poisons is mentioned in 85 of 1763 agreements on wolves and other predators (5% prevalence). In 49 of these 85 agreements (58%) the poison is specified, of which 48 refer to the use of strychnine sensu lato (12 about vomica nut and 36 about the active principle). In the 19th century, 66 of the 85 agreements about poisons (78%) were documented (in 30 municipalities), with a prevalence of 8-13% in the second half of the century. The use of vomica nut is first time recorded in 1814 in Valencia de Alcántara, and that of strychnine sensu stricto in 1850 in Alconchel (one of the oldest documented dates in Spain). Strychnine use increased notably from 1861, which likely had a negative impact on the population density of the wolf in Extremadura. Such an increase was promoted by the State Administration, pressured in turn by powerful factions of the livestock sector, and its execution fell to the local authorities. El lobo Canis lupus y otros carnívoros fueron ferozmente perseguidos en el pasado por los daños que ocasionaban al ganado y la caza. Entre los métodos usados para su control se encontraban los venenos. Aquí estudiamos la tipología de los venenos empleados en Extremadura (España) durante cuatro siglos (XVI-XIX), su prevalencia y los municipios donde se aplicaron. Para ello revisamos los Libros de Acuerdos municipales de más de 200 ayuntamientos de Extremadura y su entorno. En el periodo estudiado se menciona la utilización de venenos en 85 de 1763 acuerdos sobre lobos y otros depredadores (5% de prevalencia). En 49 de esos 85 acuerdos (58%) se especifica el veneno, de los cuales 48 se refieren al uso de la estricnina sensu lato (12 de nuez vómica y 36 del principio activo). En el siglo XIX se documentan (en 30 municipios) 66 de los 85 acuerdos sobre venenos (78%), con una prevalencia del 8-13% en la segunda mitad del siglo. El uso de nuez vómica se registra por primera vez en 1814 en Valencia de Alcántara, y el de estricnina sensu stricto en 1850 en Alconchel (una de las fechas más antiguas documentadas en España). El empleo de la estricnina aumentó notablemente a partir de 1861, lo que tuvo que impactar negativamente en la densidad poblacional del lobo en Extremadura. Tal aumento se fomentó desde la Administración del Estado, presionada a su vez por poderosas facciones del sector ganadero, recayendo su ejecución en las autoridades locales.
First data of the Iberian Blephariceridae as floral visitors in the Pyrenees (Lérida, Spain) (Insecta, Diptera)
Authors: Lara Ruiz José
Published: April 2023

Data on the floral visits of blepharicerid dipterans in a hygrophilous and riparian megaforb of the Pyrenees (Lérida, Spain) are provided. Up to 10 species, one of the genus Blepharicera and nine of Lipoineura Iberian Blephariceridae are generalist anthophiles. The study of their pollen charges shows that potential pollinators are possible, which shows that this group of flies is currently undervalued as pollinators. Se aportan datos de las visitas florales de dípteros blefaricéridos en un megaforbio higrófilo ripario del Pirineo (Lérida, España). Hasta 10 especies, una del género, Blepharicera y nueve de Liponeura de Blephariceridae ibéricos son antófilas generalistas. El estudio de sus cargas polínicas evidencia que son posibles polinizadores potenciales, lo cual demuestra que este grupo de moscas está actualmente infravalorado como polinizadores.
Patterns of odonata assemblages in lotic and lentic systems in the Sanabria glacial lake complex in Sierra Segundera (NW Spain). Diversity and biogeographical analysis
Authors: Morales Javier , Negro A.I. , Lizana Miguel
Published: April 2023

We studied the community of odonates on the southern watershed of the Sierra Segundera glacial lake complex, from the valley area (Tera river and Sanabria lake, 1000 m.a.s.l.) to the high mountain lakes and peat bogs (>1500 m.a.s.l.). The maximum richness was detected at the source of the River Tera from the lake, while on the east coast and part of the south coast there are no odonata populations or breeding and emergence habitats; this is due to the tourist pressures on the shoreline. Eighteen taxa were found to reproduce in the lake, including the endangered species Macromia splendens. Only Sympetrum flaveolum, Aeshna juncea and Enallagma cyathigerum were located exclusively at altitude mountain range. The specific turnover among ecosystems is from 30 to 14, in a 700 m gradient from the valley to the lake complex. Adults were captured in flight between weeks 18 and 44 of the calendar year. The circum-mediterranean biogeographical component dominates with species of mediterranean-western, franc-iberian and ibero-maghreb distribution, but with euro-siberian, holarctic and palaearctic species distribution; and all the holarctic chorotype species Known in Spain were recorded. No African migratory dragonflies in meridional drift were found in the three summers sampled. Se estudió la comunidad de odonatos en el complejo lacustre glaciar de la vertiente meridional de Sierra Segundera, desde el valle (río Tera y lago de Sanabria, 1000 m.s.n.m.) hasta las lagunas y turberas de alta montaña (>1500 m.s.n.m.). La riqueza máxima se detectó en la salida del río Tera desde el lago, mientras que en el litoral este y parte del sur del mismo no existen poblaciones de odonatos ni hábitats de reproducción y emergencia debido a las presiones turísticas sobre el litoral y la ribera. Se comprobó la reproducción de 18 taxones en el lago, incluyendo la especie amenazada Macromia splendens. Únicamente Sympetrum flaveolum, Aeshna juncea y Enallagma cyathigerum se localizaron con exclusividad en la montaña. Se capturaron adultos en vuelo entre las semanas 18 y 44 del año natural. El recambio específico entre ecosistemas es de 30 a 14, en un gradiente de 700 m desde el valle al complejo lacustre. Domina el componente biogeográfco circunmediterráneo con especies de distribución mediterráneo-occidental, franco-ibérica e ibero-magrebí, con especies eurosiberianas y de distribución holártica o paleártica; y se hallaron todas las especies de corotipo holártico conocidas en España. No se encontraron libélulas africanas migradoras en deriva meridional en ninguno de los tres veranos muestreados
Manifestaciones dermatológicas por Covid-19 y su aporte en la comprensión de la enfermedad
Authors: Botello Heliana , Zamudio Barrientos Adriana , Gahona Naranjo Manuel Eduardo
Published: April 2023

La enfermedad por coronavirus (Covid-19) presenta compromiso multisistémico y hasta en el 20% de los casos puede exhibir signos dermatológicos. Se realiza una revisión narrativa de la literatura acerca de las principales manifestaciones mucocutáneas asociadas a la infección por Covid-19. También se describen brevemente los mecanismos fisiopatológicos y se lleva a cabo una clasificación de las lesiones en maculopapulares, urticariales, vesiculoampollosas, tipo pernio, livedo necróticas, vasculíticas, con compromiso del folículo piloso, ungular u oral. Se presentan sus principales características clínicas, histopatológicas y tratamientos.
Respeto por el colega
Authors: Maya Mejía José María
Published: April 2023

Presentación del caso de un médico especialista, que solicita al director del hospital se revise su asignación salarial, porque ha encontrado que esta es igual a la de otros especialistas y él considera que es injusto, dado que las actividades que realiza en la institución son más complejas y producen más estrés que las llevadas a cabo porsus colegas.El médico director lleva el caso a estudio por parte de la comisión de personal del hospital y del comité de ética hospitalaria. Ambos comités estudian la solicitud y emiten el concepto al médico director para la toma de decisiones al respecto. 
Se analiza el caso desde la perspectiva de ética médica y de las buenas prácticas en el manejo y la remuneración del talento humano en salud.
Brote de viruela símica en Colombia: ¿por qué y cómo contener su diseminación?
Authors: Saavedra Carlos
Published: April 2023

La viruela  es una enfermedad infecciosa endémica en áreas de África central y occidental. Es reconocida desde 1970, cuando se identificó en la República Democrática del Congo, en un niño de 9 meses de vida, sin historia de vacunación contra la viruela. Los estudios posteriores han mostrado que existen dos clados diferentes del virus, denominados de acuerdo con el lugar de su localización: clado I, en la cuenca del Congo, y los clados IIA y IIB, de África occidental (1). Desde el 23 de julio de 2022, la Organización Mundial de la Salud (OMS) declaró el brote actual de viruela símica como una emergencia de salud pública de importancia internacional (2). Su seguimiento ha permitido establecer que la epidemia actual está relacionada con el clado IIB, con variaciones enzimáticas que editan el RNAm (1).