bluuebunny/crossref_metadata_2025 huggingface dataset:
A lectotype for the Scottish Middle Devonian (Givetian) fish
Osteolepis panderi
and the historical problems of the genus
Osteolepis
Authors: Newman Michael J.
Published: September 2024

In 1860 Pander described a new species of fish from the Givetian of Scotland using the invalid name
Osteolepis microlepidotus
, which was a synonym of
Osteolepis macrolepidotus
. In 1948 Jarvik published a monograph on this fish, giving it the name
Osteolepis panderi
. However, he did not designate a type specimen or a type locality. This was due to Jarvik's mistake in thinking he had to choose a specimen from one of the specimens used by Pander and being unable to view Pander's collection in Saint Petersburg (then Leningrad) owing to World War II and the subsequent Cold War.
Osteolepis microlepidotus
first appeared in print in 1829, but Sedgwick and Murchison's description was inadequate for erecting a species. Shortly after, Agassiz described specimens of
O. microlepidotus
, which were later shown to be specimens of
O. macrolepidotus.
Jarvik should have chosen one of the specimens he used as he erected the species
O. panderi
. After a seven-decade delay NMS G.1903.130.35 in the National Museums of Scotland is chosen as the lectotype from the many specimens used by Jarvik in his description of the species. Skinnet Farm Quarry in Caithness, Scotland is also chosen as type locality for this species.
Groundwater flow-controlled migration of dissolved microbial gas in the Eastern Hungarian Pannonian Basin
Authors: Czauner Brigitta , Adonya Romario Albert , Márton Béla
Published: September 2024

The formation of commercial microbial gas accumulations requires specific migration and accumulation conditions which can be effectively provided by groundwater flow systems. Namely, if microbial methane can be gathered and transported in aqueous solution over large lateral distances, great amounts of free gas can be exsolved where flows turn upward, causing a decrease in solubility. Based on this concept and the flow pattern of regional scale topography-driven groundwater flow systems, the present study built a simplistic 2D model in MS Excel including a methane solubility database with 32 000 data points. The model can calculate the required flow pathway length to saturate groundwater with methane, the amount of free gas that can be released in a potential accumulation zone and the necessary time interval for the whole process. Application of the model was demonstrated based on the geological and hydrogeological conditions of a study area in the Central Pannonian Basin (Hungary), focusing on the Hajdúszoboszló gas field. In light of the upscaled results of the 2D model, the known microbial gas accumulations of the study area could be charged according to the model. In addition, parameter sensitivity analysis also provided valuable insights into the complex mechanisms of microbial gas migration.
CO
2
geological storage potential in the Croatian part of the Pannonian Superbasin
Authors: Saftić Bruno , Kolenković Močilac Iva , Cvetković Marko , Vulin Domagoj
Published: September 2024

In the continental part of Croatia, oil and gas have been discovered in more than 60 locations. Most reservoirs are in the Neogene/Quaternary basin infill, but the largest ones are found in the basement rocks. Decades of exploration have left a significant vintage dataset and substantial knowledge of the subsurface geology and reservoir properties. Since 2005, research efforts have been redirected towards CO
2
geological storage capacity estimates, and the first results were obtained relatively quickly. All identified potential storage objects – deep saline aquifers, depleted hydrocarbon fields and oil reservoirs that are suitable for CO
2
enhanced oil recovery (CO
2
-EOR) – can be regarded as prospective. The deep saline aquifers are defined on a regional scale and their estimated capacity is the highest (2584 Mt), but this is ‘theoretical capacity’ that can only be used to outline the total resource base. The storage capacity estimated for the selected 14 depleted hydrocarbon fields sums to 143.6 Mt, and this is a viable capacity that might be developed as soon as a particular field stops with production, but the most promising storage objects are the seven fields that have reservoirs suitable for CO
2
-EOR operations. The most recent models have revealed that seven active EOR fields operating in parallel between 2025 and 2040 could store up to 1.2 Mt CO
2
a
−1
, while producing
c.
1.2 Mt a
−1
of additional oil. This is very high for a country with only 5.5 Mt CO
2
a
−1
in point sources.
Exploring the Benefits and Applications of Video-Span Selection and Search for Real-Time Support in Sign Language Video Comprehension among ASL Learners
Authors: Hassan Saad , de Lacerda Pataca Caluã , Amin Akhter Al , Nourian Laleh , Navarro Diego , Lee Sooyeon , Gordon Alexis , Watkins Matthew , Tigwell Garreth W. , Huenerfauth Matt
Published: September 2024

People learning American Sign Language (ASL) and practicing their comprehension skills will often encounter complex ASL videos that may contain unfamiliar signs. Existing dictionary tools require users to isolate a single unknown sign before initiating a search by selecting linguistic properties or performing the sign in front of a webcam. This process presents challenges in extracting and reproducing unfamiliar signs, disrupting the video-watching experience, and requiring learners to rely on external dictionaries. We explore a technology that allows users to select and view dictionary results for one or more unfamiliar signs while watching a video. We interviewed 14 ASL learners to understand their challenges in understanding ASL videos, strategies for dealing with unfamiliar vocabulary, and expectations for an
in situ
dictionary system. We then conducted an in-depth analysis with eight learners to examine their interactions with a Wizard-of-Oz prototype during a video comprehension task. Finally, we conducted a comparative study with six additional ASL learners to evaluate the speed, accuracy, and workload benefits of an embedded dictionary-search feature within a video player. Our tool outperformed a baseline in the form of an existing online dictionary across all three metrics. The integration of a search tool and span selection offered advantages for video comprehension. Our findings have implications for designers, computer vision researchers, and sign language educators.
Public administration digitalization effects on corruption: Lesson learned from Indonesia
Authors: Darusalam Darusalam , Janssen Marijn , Jayanti Sri , Sitompul Renato , Said Jamaliah , Sanusi Zuraidah
Published: September 2024

The digitalization of public administrations can reduce corruption, but many efforts fail. Although the relationship between digitalization and corruption has been investigated, how corruption can be reduced in practice is given hardly any attention. Therefore, we take a different approach by investigating an in-depth case study using documents and interviewing civil servants and citizens. This study found technical and organizational issues blocking the reduction of corruption. Despite encountering technical challenges, most informants agreed that automating administrative processes and making each process step transparent resulted in less corruption. Separating concerns by having different officers conduct each process reduced corruption on the condition that direct communication between immigration officers and passport applicants was blocked. The present study concludes that organizational and technological changes should go hand in hand to reduce corruption. Specifically, the separation of concerns at the organizational and system levels is needed to prevent persons from collaborating and misusing the system. Also, regulatory modifications and suitable governance structures are necessary.
Distributed and Collaborative Lightweight Edge Federated Learning for IoT Zombie Devices Detection
Authors: Han Chunjing , Li Tong , Chen Qiuyi , Wu Yulei , Qin Jifeng
Published: September 2024

The fast development of artificial intelligence and Internet of Things (IoT) technologies has enabled various applications of smart cities, e.g., smart monitoring and surveillance. However, vulnerabilities of IoT devices bring new threats to the security of smart cities. To identify ubiquitous IoT botnet attacks, a distributed and collaborative lightweight edge federated learning model for IoT zombie devices detection is proposed, named FIOT. To reduce computational complexity and enhance the adaptability to new attack environment at the network edge, FIOT is designed in a lightweight manner based on feature dimensionality reduction and transfer learning. Three IoT botnet datasets are used to validate the effectiveness of the proposed FIOT. Experimental results show that FIOT has an accuracy loss of less than 3% in terms of F1 value compared to the centralized learning, but the training time of FIOT is only 14.3% of that of centralized learning. While ensuring high detection accuracy, the number of parameters of FIOT is compressed to 37.58% of the comparison method.
Hypomethylation-associated ELF3 helps nasopharyngeal carcinoma to escape immune surveillance via MUC16-mediated glycolytic metabolic reprogramming
Authors: Liu Yueyang , Zhou Hong , Yu Qi , Wang Qiang
Published: September 2024

We identified the functions of E74-like factor 3 (ELF3) in glycolysis and immune escape of nasopharyngeal carcinoma cells for the first time. As a transcription factor, ELF3 promoted mucin-16 (MUC16) expression by binding to its promoter, leading to the glycolysis-mediated immune escape of nasopharyngeal carcinoma (NPC) cells. Targeting the ELF3/MUC16 axis generates a superior antitumor immune response, which will help establish a novel approach to restore protective antitumor immunity for NPC immunotherapy.
Calamintha incana Methanolic Extract: Investigation of Phytochemical Composition and Antioxidant and Antibacterial Activities
Authors: Althaher Arwa R. , Shehabi Reham F. , Ameen Hanan H. , Awadallah Mirna W. , Mastinu Andrea
Published: September 2024

Calaminthaincana, a medicinal plant traditionally used for its therapeutic properties, has been investigated for its phytochemical constituents and biological activities. Through a specific LC‐MS/MS analysis method, the phytochemical constituents of Calamintha incana methanolic extract have been identified and quantified. The 2,2‐diphenyl‐1‐picrylhydrazyl method was used to measure the antioxidant properties. The antibacterial properties of this extract have been tested against four harmful bacteria using disc diffusion and the minimum inhibitory concentration methods. A colorimetric assay has evaluated the total phenolic and flavonoid content. The extract contained 34 compounds, with linolenic acid (11.2%) and myristic acid (10.3%) being the most abundant. Despite the low phenolic and flavonoid content, the extract exhibited antioxidant activity with an IC50 of 96.8 ± 0.3 μg/mL. Moreover, the extract demonstrated potent antimicrobial properties against B. cereus and S. aureus, with minimum inhibitory concentrations of 11.8 and 21.5 μg/mL, respectively. These robust results underscore the potential of C. incana methanolic extract in the development of effective antibacterial agents.
Health Literacy and Healthcare Seeking with Lung Cancer Symptoms among Individuals with Different Smoking Statuses: A Population‐Based Study
Authors: Sele Sætre Lisa Maria , Balasubramaniam Kirubakaran , Aaby Anna , Rasmussen Sanne , Søndergaard Jens , Jarbøl Dorte Ejg
Published: August 2024

Objective. To estimate proportions of contacts to the general practitioner (GP) among people with specific and nonspecific lung cancer symptoms, respectively, in the Danish general population and to analyse the associations between health literacy and these contacts based on smoking status. Methods. A total of 67,280 randomly selected individuals aged ≥40 years were invited to a survey concerning symptoms and healthcare seeking. This study included lung cancer symptoms, GP contacts, smoking status, four aspects of health literacy, and socioeconomics. Descriptive statistics and multivariable logistic regression models were applied. Results. Of 22,055 respondents, 23% reported at least one specific lung cancer symptom, while 47% reported at least one nonspecific symptom. GP contacts ranged from 30% (tiredness) to 60% (shortness of breath). Individuals who currently smoke had lower odds of GP contacts. The health literacy aspect “Feeling understood and supported” increased the likelihood of GP contact, while “Having sufficient information” decreased the likelihood. Smoking status did not modify these associations. Conclusion. Efforts targeting individuals at risk of postponing healthcare seeking with lung cancer symptoms are needed. This study highlights aspects of health literacy that may be addressed in interventions increasing both individuals and community‐based health literacy responsiveness and enhanced chances of timely healthcare seeking.
Supplementary Table S3 from Race-Related Differences in Sipuleucel-T Response among Men with Metastatic Castrate–Resistant Prostate Cancer
Authors: Heath Elisabeth I. , Thakur Archana , Chen Wei , Hwang Clara , Paller Channing J. , Cackowski Frank C. , Boerner Julie L. , Heilbrun Lance , Smith Melanie P. , Schalk Dana L. , Schienschang Amy , Whitaker Sarah A. , Polend Amanda , Smith Daryn , Vaishampayan Ulka N. , Dickow Brenda , Lum Lawrence G.
Published: August 2024

Summary of significant responses before and after sipuleucel-T in mCRPC patients.
Supplementary Figure S3A from Race-Related Differences in Sipuleucel-T Response among Men with Metastatic Castrate–Resistant Prostate Cancer
Authors: Heath Elisabeth I. , Thakur Archana , Chen Wei , Hwang Clara , Paller Channing J. , Cackowski Frank C. , Boerner Julie L. , Heilbrun Lance , Smith Melanie P. , Schalk Dana L. , Schienschang Amy , Whitaker Sarah A. , Polend Amanda , Smith Daryn , Vaishampayan Ulka N. , Dickow Brenda , Lum Lawrence G.
Published: August 2024

Waterfall plot showing PSA change from baseline to nadir.
Supplementary Figure 5 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
Authors: Chouleur Tiffanie , Emanuelli Andrea , Souleyreau Wilfried , Derieppe Marie-Alix , Leboucq Téo , Hardy Serge , Mathivet Thomas , Tremblay Michel L. , Bikfalvi Andreas
Published: August 2024

K67 staining in knock-out and PRL2 overexpressing cells.
Herpes zoster ophthalmicus: Impfung kann steigenden Erkrankungszahlen entgegenwirken
Authors: Pleyer Uwe
Published: September 2024

Herpes zoster (HZ) is caused by reactivation of latent infection of varicella zoster virus (VZV) in sensory (cranial, dorsal root) ganglia. Major risk factors for HZ are increasing age and immunosuppression. HZ ophthalmicus (HZO) is a subset of HZ with involvement of the ophthalmic division of the fifth cranial trigeminal nerve. Approximately 4–20% of patients with HZ develop HZO. Approximately 50% of patients with HZO develop ocular disease, among whom up to 25% develop chronic or recurrent disease. Common manifestations of ocular disease include conjunctivitis, keratitis, and uveitis, whereas optic neuropathy and retinitis are uncommon. Due to the potential for vision impairment, ocular involvement requires urgent ophthalmic consultation. Early recognition and timely treatment with antivirals may prevent ocular complications. HZO is preventable by vaccination against HZ. Vaccine efficacy/effectiveness studies have been largely conducted for HZ with few studies assessing HZO. Both the recombinant adjuvanted vaccine (RZV) and live-attenuated vaccine (ZVL) significantly reduce the incidence of HZ and HZO in older adults. RZV is more effective than ZVL. Data on the effectiveness of vaccines for prevention of recurrent disease in patients with HZO are limited; however, vaccination is recommended. Despite recommendations to vaccinate individuals likely to benefit from an HZ vaccine, coverage for adults remains suboptimal. Barriers to vaccination include patient beliefs about HZ or HZ vaccines, and factors related to healthcare providers. In particular, the lack of a recommendation from their primary care physician is often cited by patients as a reason for remaining unvaccinated. By encouraging vaccination against HZ, physicians not only prevent HZ and HZO but also potential vision loss due to HZO.
Aktueller Stand zur Versorgungslage von Patientinnen und Patienten mit geografischer Atrophie
Authors: Zimmermann Julian Alexander
Published: September 2024

Die Europäische Arzneimittel-Agentur (EMA) gab in einer Stellungnahme am 27. Juni 2024 bekannt, dass sie empfiehlt, die Zulassung von Syfovre® auf dem europäischen Markt zu verweigern. Bei Syfovre (Pegcetacoplan) handelt es sich um ein Arzneimittel zur Behandlung der geografischen Atrophie (GA), das von Apellis vertrieben wird. Als Begründung nannte die EMA, dass die vorliegenden Studienergebnisse auf keinem klinisch bedeutsamen Nutzen für die Patienten hindeuteten. Dadurch kam die EMA zu dem Schluss, dass kein positives Nutzen-Risiko-Verhältnis von Syfovre bei der Behandlung der durch AMD verursachten GA nachgewiesen werden konnte. Am 11. Juli 2024 beantragte Apellis eine erneute Prüfung der Stellungnahme der EMA.
Outcomes of Patients with Critical Limb Ischemia and Chronic Kidney Disease: A National Perspective
Authors: Rivera Frederick Berro , Aparece John Paul , Marie Ruyeras Jade Monica , Menghrajani Rajiv Hans , Ybañez Mc John , Candida Honorio Emily Grace , Albert Ramirez Damayo Jeffrae Isaac , Li Guowei , Dwivedi Alok , Puentespina Rachel Anne , Talili Pauline Julia , Cu Joanna Pauline , Alfonso Marañon Joson Josiah Juan , Baoy Bantayan Nathan Ross , Lerma Edgar V. , Collado Fareed Moses , Ong Kenneth , Vijayaraghavan Krishnaswami , Kazory Amir
Published: September 2024

Introduction: Studies exploring the relationship between peripheral arterial disease (PAD), critical limb ischemia (CLI), and chronic kidney disease (CKD) and its effect on in-hospital outcomes are limited. We aimed to analyze the outcomes of patients with CKD and PAD who are admitted for CLI. Methods: We utilized the National Inpatient Sample (NIS) to capture hospitalizations for CLI from 2012 to 2020 and then identified cases with concomitant CKD. The primary outcome was mortality, and secondary outcomes were cerebrovascular accident, major bleeding, vasopressor requirement, percutaneous coronary intervention, cardiac arrest, acute respiratory failure, transfusion, length of stay, and total hospital charges. Multivariable logistic regression was performed to adjust for covariates. Results: A total of 441,245 patients with CLI were identified, of which 122,370 (27.7%) reported concomitant CKD. Patients with CKD had higher in-patient mortality (odds ratio [OR] 1.68, 95% confidence interval [CI], 1.17–1.68, p < 0.001), vascular complications (OR 1.31, 95% CI, 1.17–1.48, p < 0.001), acute kidney injury requiring hemodialysis (OR 3.17, 95% CI, 2.64–3.80, p < 0.001), and major bleeding (OR 1.12, 95% CI, 1.05–1.19, p < 0.001). Patients with CKD underwent minimally invasive endovascular therapy (31.08% vs. 36.73%, p < 0.0001) and invasive procedures (14.73% vs. 23.55%, p < 0.0001) less often. PAD-CLI with CKD was associated with major (20.54% vs. 16.17%, OR 1.04; p < 0.0001) and minor (26.87% vs. 19.53%, OR 1.2, p < 0.0001) amputations more often. Conclusion: Patients admitted for PAD-CLI with concomitant CKD have significantly higher in-hospital mortality as compared to patients without CKD. Moreover, patients with CKD and PAD-CLI are less likely to receive revascularization and more likely to undergo amputation.
Ultra-Processed Foods Consumption Is Positively Associated with the Clinical Activity of Inflammatory Bowel Diseases: A Cross-Sectional Single-Center Study
Authors: Sarbagili-Shabat Chen , Zelber-Sagi Shira , Isakov Naomi Fliss , Hirsch Ayal , Ron Yulia , Grinshpan Laura Sol , Anbar Ronit , Bromberg Ahuva , Thurm Tamar , Maharshak Nitsan
Published: September 2024

Introduction: Western diet pattern and its food components have been suggested to impact inflammatory bowel diseases (IBDs) clinical course. However, the importance of food processing level is uncertain. We aimed to evaluate whether the intake of foods with varying processing levels is associated with disease activity in IBD patients. Methods: This cross-sectional study was performed at a tertiary center between August 2019 and June 2022. Consecutive adult IBD patients were recruited. Clinical disease activity was defined using HBI (Crohn’s disease) and SCCAI (ulcerative colitis). Dietary intake was assessed using a food frequency questionnaire (FFQ) and a dedicated validated processed food questionnaire (PFQ) that categorizes dietary intake into three groups of processed food levels: unprocessed/minimally processed, processed, and ultra-processed. Adjusted odds ratios for active disease were determined using a multivariable logistic regression. Results: A total of 242 IBD patients (62.8% Crohn’s disease patients) were enrolled, of whom 73.1% were in clinical remission. A higher (upper tertile vs. lowest tertile) unprocessed/minimally processed foods consumption was negatively associated with active disease (OR = 0.38, 95% CI: 0.14–0.99), while high consumption of ultra-processed foods (UPFs) was positively associated with clinically active disease (OR = 3.82, 95% CI: 1.49–9.8). Consumption of UPF groups, almost invariably, was positively associated with clinically active disease, while consumption of the ultra-processed meats group had the strongest association (OR = 4.45, 95% CI: 2.07–9.79). Conclusion: Higher consumption of UPFs is positively associated with clinically active IBD, while higher consumption of unprocessed/minimally processed foods may be protective. Prospective studies are needed to confirm these associations.
The First Case of Lynch Syndrome-Associated Penile Cancer Harboring a Heterozygous PMS2 Frameshift Variant
Authors: Wu Zhiqiang , Xiao Liang , Qiang Jibin , Chen Yan , Liu Dujuan , Chen Deyi , Chen Zhihong
Published: September 2024

Introduction: Penile squamous cell carcinoma (PSCC) is a rare malignancy in men with poor survival in metastatic disease. Lynch syndrome (LS) is a cancer predisposition, autosomal-dominant, inherited disorder that arises from loss of function variants in mismatch repair genes. Case Presentation: Here, we reported a PSCC patient who was suspected with LS caused by a heterozygous PMS2 D526Afs*69 variant. A 57-year-old male with PSCC underwent pelvic lymph node dissection and bilateral groin lymph node dissection due to metastatic disease. He has a family history of colon cancer and brain cancer. Comprehensive genomic sequencing of his tumor specimen identified 19 somatic mutations with a high tumor mutation burden (14.03 mutations per Mb) and a high frequency of microsatellite instability. Additionally, a germline PMS2 D526Afs*69 mutation was identified in the peripheral blood sample. Immunohistochemistry analysis showed complete loss of PMS2 and MLH1 expression in his tumor. Conclusion: These observations provided evidence suggesting that PSCC could be part of the LS spectrum.
O lugar de enunciação de bebês em sofrimento psíquico e com desfechos distintos de linguagem aos dois anos
Authors: Hoogstraten Antônia Motta Roth van , Parlato-Oliveira Erika Maria , Souza Ana Paula Ramos de
Published: September 2024

Este artigo analisa a singularidade linguística e psíquica de dois bebês com desfecho de linguagem distintos aos dois anos. Para análise utilizou-se a entrevista inicial e continuada, os Indicadores Clínicos de Referência/Risco ao Desenvolvimento Infantil (IRDI), os Sinais Enunciativos de Aquisição da Linguagem (SEAL), além de filmagens da interação entre mãe e bebê. Os resultados indicaram que apenas um dos casos houve superação do sofrimento psíquico e atraso na linguagem a partir do segundo ano de vida.  Tanto o exercício das funções parentais quanto as condições dos bebês são fatores importantes em sua constituição psíquica e linguística, o que traz reflexões interdisciplinares importantes acerca da singularidade na relação entre esses dois aspectos do desenvolvimento infantil.
Acompanhamento escolar de crianças com entraves estruturais na constituição psíquica: contribuições e desafios
Authors: Siqueira Luiza Davini de
Published: September 2024

Este artigo parte da contextualização do movimento inclusivo e das conquistas em termos de legislação no Brasil, para analisar, com a ajuda do referencial psicanalítico, cenas vividas em uma experiência de acompanhamento escolar de uma criança com entrave estrutural na sua constituição psíquica. Abordam-se contribuições e desafios do acompanhamento escolar na inclusão desses alunos e alunas, a importância da escola como local de subjetivação e a riqueza da interação entre os pares criança-criança nesse processo. Conclui-se que a inclusão escolar não pode se pautar na busca de que “tudo seja igual para todos”; há que se trabalhar com as diferenças para chegar à igualdade de oportunidades e ao direito fundamental à educação. Cabe à escola manter a elasticidade em seu currículo para que todos os estudantes possam acessá-lo, cada um a seu modo, construindo sentido e aprendizagem na sua experiência escolar.
A cobertura noticiosa de crianças e jovens em códigos de ética
Authors: Martins Paulo
Published: September 2024

Este artigo incide na abordagem das normas inscritas em códigos de ética jornalística sobre a cobertura de casos envolvendo cidadãos menores de idade, com o objetivo de identificar os valores e princípios estabelecidos, bem como a conduta profissional prescrita. A investigação baseia-se na análise de conteúdo de 200 códigos de diversas regiões do mundo. Concluiu-se que 128 (64%) destes apresentam referências diretas ao tema, como respeito pelo melhor interesse da criança, proteção da privacidade, consentimento prévio para contato ou condições de realização de entrevistas. A principal preocupação detectada foi a avaliação dos danos causados a crianças e jovens e a ocultação da identidade, o procedimento mais frequentemente recomendado para sua proteção.
Os desafios de comunicação pública das ciências na mutação climática
Authors: Brianezi Thaís
Published: September 2024

Este ensaio problematiza os desafios de comunicação pública das ciências na mutação climática a partir do pensamento de Bruno Latour. O texto está dividido em cinco partes: (1) discute a desinformação e o negacionismo climático; (2) foca na importância de se trabalhar a comunicação pública das ciências iluminando os processos de pesquisa e suas controvérsias; (3) debate por que é preciso superar o mito do conhecimento objetivo e aterrar a produção e a comunicação dos diversos saberes; (4) aborda a relação intrínseca entre ciência, discurso e representação; (5) apresenta práticas educomunicativas que oferecem pistas para enfrentar epistemológica e empiricamente esses desafios.
O jornalismo como arma de “ação psicológica”: Folha de S.Paulo e a luta contra a “subversão” na ditadura
Authors: Bonsanto André
Published: September 2024

O objetivo deste trabalho é realizar uma análise sobre o papel da Folha de S.Paulo na chamada luta “antisubversiva” da ditadura civil-militar no Brasil, tendo como foco uma campanha de “ação psicológica” intitulada “União Contra a Violência”, realizada pelo jornal em julho de 1969. Desta forma, procuramos avançar nas análises sobre o papel do jornalismo como agente legitimador dos aparatos repressivos do Estado, atestando o protagonismo exercido pela Folha em um dos períodos de maior recrudescimento do regime, – durante o contexto de criação da Operação Bandeirante (Oban) – bem como a clara sintonia que existia àquele momento entre a empresa e os preceitos doutrinários da ditadura.
Objeto de memória como categoria de análise de capas de disco
Authors: Vargas Herom
Published: September 2024

Based on authors from memory, communication, and culture studies, this study discusses the notion of the object of memory as a category in the analysis of long-playing album covers (LP/vinyl) within the relations that involve cultural practices, music, and materialities. As cultural representations shared by artists, record labels, and fans, covers articulate visual memories triggered over time (from the past to the present) by the meanings attributed to them, their presence, and their materiality (wear, imperfections, etc.). This study will observe how some authors treat the term object of memory or surround the notion to reflect on the effectiveness of the category in the analysis of album covers throughout this dialogue.
O protagonismo negro enfim faz sucesso: a autorrepresentação em Medida Provisória e Marte Um
Authors: Schvarzman Sheila
Published: September 2024

This study points out an unprecedented media event: in 2022, two films directed and acted by Black individuals reached the mainstream. Executive Order by Lázaro Ramos, with 500,000 viewers and Mars One by Gabriel Martins, the Brazilian nominee for the Oscars. These works, differing in aesthetics and objectives, pointed to paths, constructing counter-hegemonic visualities regarding the Black and poor populations of Brazil and engaged with the public and critics. By briefly examining the Black presence in Brazilian cinema and the diverse experiences of its creators, we highlight how the construction of these films establishes, whether in form of dystopia or everyday life, other places, and images in a political gesture of rejecting violence.
Qoheleth as a Realist
Authors: Dell Katharine J.
Published: August 2024

On a three stage “ladder,” from humanism to scepticism to pessimism, Ecclesiastes has traditionally been regarded as the last of those three. Many recent studies, however, have challenged this assessment, replacing humanism with optimism and presenting a stark choice between the two extremes of optimism and pessimism. In this paper it is argued that a middle way can be found, using the language of “realism.” How to define “a realist” and what this means for understanding Qoheleth is explored. Examples of Qoheleth’s pragmatic advice, experiential starting point, and continual balancing of life’s options are aired, and key indicators of his realism are found. These are demonstrated first, in his use and placement of the three major poems in the book, second, in his choice of phrases around “knowledge,” and third, in his use of exemplifying stories that ground his more abstract musings in a concrete reality.
Erratum: Huang, Q.L., Fei, W.Q., Yuan, Q. & Yang, Q.E. (2024) Clematis armandi var. kiangnanensis (Ranunculaceae) is not synonymous with C. armandi, but C. finetiana, a widely distributed species in China. Phytotaxa 660 (3): 259–277.
Authors: HUANG QIAO-LAN , FEI WEN-QUN , YUAN QIONG , YANG QIN-ER
Published: September 2024

N/A
Antioxidant and Antiplasmodial Potentials of Methanol Bark Extract of Entada africana Via in Vitro Approaches
Authors: Olusola Adesayo , Okoh Ehisdiame , Ekun Oluwafemi , Elekan Ayodele , Fakoya Akindele , Olusola Augustine
Published: September 2024

Plasmodium parasites, which cause malaria, continue to pose a serious threat to global health, necessitating the continuous search for novel antimalarial agents. Oxidative stress has also been linked to the pathophysiology of malaria. Entada africana is a plant known for its ethnomedicinal uses in treating various ailments associated with inflammation including malaria. This study aimed at evaluating the antiplasmodial and antioxidant potentials of methanol bark extract from Entada africana (MBEEA). In vitro approaches were adopted for the study. Plasmodium falciparum-infected erythrocyte samples were cultured in Roswell Park Memorial Institute (RPMI) 1640 media under anaerobic conditions for 72 hours. Eighteen test tubes were labeled and grouped into three replicates per group. Group I (untreated), Group II, and III were treated with chloroquine (CQ) and artemether (AR) at a concentration of 5 mg/dL. Group IV, V, and VI were treated with the extract at respective concentrations of 5 mg/dL, 10 mg/dL, and 20 mg/dL for 72 hours. The parasitemia count and the percentage parasitemia inhibition were determined by microscopic examination of Giemsa-stained smears. The antioxidant potential of the extract was assessed using in vitro assays, including superoxide radical scavenging activity (SRSA), hydroxyl radical scavenging activity (HRSA), 1,1-diphenyl-2-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP). Microscopic examination of the treated samples revealed varying degrees of parasitemia inhibition. Group II and III treated with CQ and AR demonstrated a considerable reduction in parasitemia count with percentage inhibition of 100% and 83% respectively. The E. africana extract showed a concentration-dependent effect on parasitemia count. At 5 mg/dL, the extract exhibited 50% parasitemia inhibition, which increased to 100% at 10 mg/dL, and 20 mg/dL respectively. The MBEEA demonstrated significant in vitro antioxidant activities by scavenging DPPH, SRSA, and hydroxyl radical compared to the standard antioxidant (ascorbic acid). MBEEA thus exhibit potent antioxidant and antiplasmodial properties. This plant is therefore offers to be a promising medicinal plant in the treatment of malaria, hence it is recommended as potent antiplasmodial plant usable for treating malaria.
A Literature Study of Emergency Material Dispatch Models and Optimisation in the Context of Natural Disasters
Authors: Ruoqi Zhou , Manzhen Duan
Published: September 2024

The recurrent occurrence of natural disasters has brought into sharp focus the urgent need for the expedient distribution of emergency materials. In the aftermath of a disaster, the swift and precise distribution of essential emergency supplies is of the utmost importance in ensuring the basic survival needs of the affected population are met, minimising the impact of the disaster and maintaining social stability. In order to provide a comprehensive overview of the research progress in the field of emergency supplies dispatching after natural disasters, we employ the knowledge graph analysis software VOSviewer to investigate the optimisation issues pertaining to the emergency supplies dispatching model, taking into account the inherent uncertainty, from a multi-objective standpoint and across a range of algorithms. A total of 375 literature sources were included in the China Knowledge Network database for review. The research objectives, methods and conclusions of the representative literature on hot spots at home and abroad were subjected to analysis. The review examines the research objectives, methodologies and conclusions of the most prominent literature on the subject, both domestic and international, and analyses the current status of research on the scheduling of emergency materials in the context of natural disasters. By synthesising these findings, we aim to identify gaps in existing research and suggest directions for future endeavours to promote a more resilient and effective emergency management system that can respond rapidly to the ever-changing needs of disaster-affected communities.
Power Wheeling Pricing Considering Congestion in Power Network: A Review
Authors: Ayorinde Akangbe , Abiola Adepoju , Isaiah Adebayo
Published: September 2024

Limited capacity of the power system infrastructure has a limiting effect on the quantity of electrical power that can be transmitted thereby resulting in the system been congested which also affects the quality of electrical energy supplied. Congestion is an undesired effect in power system with serious economic, reliability and security effect on power system infrastructure, which are yet to be adequately quantify in term of cost. Congestion occurrence and management on the power system network has been studied extensively, causes of congestion and various management techniques have been proposed which are at great financial consequences. While setting transmission wheeling prices, congestions are not adequately considered, nor are the management methods accurately financially compensated. Some wheeling pricing techniques however recognises the short coming and takes into consideration the financial cost of congestion and it’s management methods when setting their transmission wheeling costs. This paper is a review of wheeling methods that takes into consideration the cost of congestion and the management techniques when setting wheeling prices and makes a recommendation using financial and economic implication of the occurrence of congestion and the management techniques adopted in reducing the impact when setting wheeling prices, in order to encourage investment into the transmissions system infrastructures.
Imaging the Impact: Computed Tomography Thorax in COVID-19 - A Comprehensive Review and Clinical Analysis
Authors: Maqbool Yasmeena
Published: September 2024

This comprehensive review and clinical analysis explore the pivotal role of thorax computed tomography (CT) in the context of COVID-19. As the world grapples with the ongoing pandemic, the need for effective diagnostic tools and management strategies remains paramount. This review meticulously examines the impact of thorax CT imaging on the understanding, diagnosis, and clinical management of COVID-19. The review encompasses an extensive analysis of the existing literature, shedding light on the nuances of thorax CT findings in COVID-19 patients. It explores the characteristic imaging features, such as ground-glass opacities, consolidations, and other pulmonary abnormalities, providing insights into the pathophysiology of the disease. Furthermore, the clinical analysis component synthesizes data from diverse studies to elucidate the diagnostic accuracy and sensitivity of thorax CT, particularly in cases where molecular testing may present challenges. The review also delves into the role of thorax CT in early detection, risk stratification, and longitudinal monitoring of patients with COVID-19, offering valuable perspectives for healthcare professionals. Importantly, considerations of radiation exposure and ethical use of thorax CT are addressed, emphasizing the judicious integration of imaging into clinical practice. The article concludes with practical recommendations for optimizing the utility of thorax CT in the broader context of COVID-19 diagnosis and patient care.
Agranulocytosis Induced by Overdosage of Mercaptopurine: A Case Report
Authors: Bardi Touria , Ouarradi Assia , Rouhi Salma , Quiddi Wafae , Sayagh Sanae
Published: September 2024

Drug-induced agranulocytosis (DIAG) is a rare but potentially fatal hematological complication. Thiopurines, such as mercaptopurine (6-MP), are widely used in the treatment of chronic inflammatory bowel diseases (IBD), but can cause myelotoxicity due to the accumulation of active metabolites. We report the case of a 48-year-old woman with ulcerative colitis who developed severe agranulocytosis following an accidental overdose of 6-MP. The patient presented with febrile pancytopenia with a neutrophil count of 0.04 G/L. Bone marrow examination revealed normal cellularity with an inversion of the maturation pyramid of the granulocyte lineage. A treatment combining growth factors (filgrastim) and antibiotics (tazobactam) was initiated, leading to progressive improvement over 5 weeks. The toxicity of 6-MP is mainly due to the accumulation of 6-thioguanine nucleotides (6-TGN). The polymorphism of the gene encoding the enzyme thiopurine S-methyltransferase (TPMT) can influence the risk of myelotoxicity. Two strategies are proposed to minimize this risk: evaluation of TPMT activity with dosage adjustment, or regular monitoring of blood counts with gradual dose increase. This case highlights the importance of rigorous biological monitoring when initiating 6-MP treatment, regardless of the TPMT test. Increased vigilance is necessary when using immunosuppressive drugs in the treatment of IBD to optimize efficacy and minimize toxicity.
3-D Modelling and Simulation of a Reservoir for Surfactant-Polymer Flooding Using Eclipse Software
Authors: Kelechi Ihekoronye , Dodo Sulaiman , Bello Adamu , Hassan Usman , Zwalatha Milton
Published: September 2024

Surfactant-polymer flooding is a tertiary enhanced oil recovery method used to recover oil that remained in the reservoir after the primary and secondary oil recovery mechanisms. Predicting the pressure in the reservoir is important for oil production as pressure changes with time. A suitable approach to achieve this task is to derive fluid flow equation based on the reservoir characteristics and solve them numerically which provide the solution to the mathematical fluid flow model (diffusivity equation). In this study, 3-D reservoir was modelled using Eclipse software. The fluid flow equations in a porous media were derived based on the simulated model and the reservoir conditions. Numerical solution using implicit formulation to solve the mathematical fluid flow model (diffusivity equation) was investigated by developing Python codes using Jupyter library to ascertain the pressure distribution for the reservoir and imported into Eclipse simulator. Simulation was carried out using surfactant-polymer and reservoir properties to determine the oil recovery. The results of the study showed that pressure increases with time as oil production continued, and water saturation decreased for the grid-cells of the reservoir. Waterflooding had oil recovery of 38.0% and water-cut of 59.0%, while surfactant flooding had oil recoveries of 42.0%, 46.5%, 49.0% and water-cut of 57.0%, 51.0%, 46.3%. In addition, polymer flooding had oil recoveries of 44.3%, 48.4%, 54.0% and water-cut of 50.0%, 45.0% and 33.0% respectively at different concentrations of 0.3%wt. 0.4%wt. and 0.5%wt.
Semiotics and Symbolic Politics in the Reception of Seventeenth-Century Art: Reflections on Guercino's Prometheus
Authors: Masone Leonardo
Published: September 2024

As happens in almost all eras, contemporary thinkers have been able to prepare new tools for understanding the historical phases that preceded them. Tools that have led to new disciplinary directions and new interpretative methods: think of semiotics which in relation to the artistic field has highlighted alternative exhibition languages for reading paintings; or to the philosophical question of symbolic politics. With these tools it has been possible to read the timeless myth of Prometheus with a decidedly original key and in the modern age we see a clear revival in the use of this myth, both in political essays, in philosophy, in literature and in art. Also because Prometheus brings with him many messages also based on how one wants to think of him, whether free to grant the flame to humanity or chained due to the punishment of Zeus. With this essay, we try to read the interpretation of Prometheus by one of the most important painters of the European seventeenth century, Giovan Francesco Barbieri known as Guercino who at the age of 25 decided to open the Academy of the Nude in his hometown, Cento between Bologna and Ferrara, for very young aspiring painters, and it is precisely in the rooms of that art school that he frescoed his first and only Prometheus in the act of granting flame to the inanimate clay statue. A gesture that marks the meaning of art considered one of the highest human virtues.
Evaluation of Growth Performance and Carcass Characteristics of Guraghe Bulls Under Various Feeding Regimes
Authors: Gudeto Aman , Tassew Berhanu
Published: September 2024

The experiment was conducted on yearling Guraghe bulls, with an average initial body weight of 111.91 ± 3.98 kg, to evaluate their growth performances and carcass characteristics under three different feeding options and to identify the most economical dietary rations. Twenty-one experimental bulls were randomly assigned to three dietary rations: T1 = Rhodes grass hay ad-libitum + 20% molasses + 40% wheat bran + 40% noug seed cake, T2 = Rhodes grass hay ad-libitum + 20% maize grain + 45% wheat bran + 35% noug seed cake and T3 = Rhodes grass hay ad-libitum + 65% wheat bran + 35% cotton seed cake. The bulls were acclimatized to the experimental diets for days, and the actual feeding trial lasted for 26 weeks. The animals’ weights were recorded at 14-day intervals. At the end of the 26 weeks three bulls from each treatment group were randomly selected for carcass evaluation. There were no significant differences (P>0.05) in live weight parameters and carcass characteristics among the treatments. The overall means for total weight gain, average daily gain, and carcass dressing percentage were 112.86 kg, 620g/day, and 57.34%, respectively. The yearling Guraghe bulls did not reach export market weight within 26-weeks of the feeding period. Additionally, the partial budget analysis indicated that fattening yearling Guraghe bulls with the current feeding options were not profitable. This suggests that fattening Guraghe bulls with the current feeding options for twenty-six months is economically not viable. It is recommended to evaluate the growth performances of Guraghe bulls with other feeding options to achieve an export market weight of 250-300 Kg.
Assessment of the Level of Utilization of Immunization Services Among Nursing Mothers in Some Local Government Areas of Benue State, Nigeria
Authors: Musa Efukun , Kitoye Gentle
Published: September 2024

The study investigated the level of utilization of immunization services among nursing mothers in some local government areas of Benue state. Descriptive cross sectional research design was adopted and multistage sampling procedure was employed. The questionnaire for the respondents titled assessment of the levels of utilization of immunization services among nursing mothers (ALUISNM). The study population consists of 1,500 nursing mothers in selected LGAs of Benue State. Mean, standard deviation were employed to analyze the data obtained from the respondents, while the null hypothesis was verified using the t-test of ANOVA. It can be deduced that the height of utilization of immunization services amongst the nursing mothers in Benue State is fair. The result that 765 (54.3%) utilized immunization services against 670 (45.7%). The result pointed out that there is high level of utilization of immunization services among women with secondary education (57.6%) followed by those with tertiary education. Based on socio economic status immunization were utilized more by women who are unemployed and self-employed with (56.0%) and (55.3%) respectively. Based on location of immunization services, utilization was more by the urban women (60.0%) than semi urban and rural women. Also based on religion utilization of immunization is higher with those of Islam traditionalist than the Christians. The utilization of immunization services and factors such as socio-economic status [F(2,(1462) = 1.139, p>0.05], location [F(2,(1462) = 2.249, p>0.05]. and religion [F(2,(1462) = 0.528, p>0.05] showed no verifiable significance differences. But there was a significant difference with regards to education [F(3,1461) = 15.773, p<0.05]. Conclusively, there was positive level of utilization of immunization services from the study and therefore recommended that issues like location of health facilities, awareness, education etc should be addressed.