bluuebunny/crossref_metadata_2025 huggingface dataset:
Study on the mechanical properties of unloading damaged sandstone under cyclic loading and unloading
Authors: Zhang Hengbin , Wang Lehua , Li Jianlin , Deng Huafeng , Xu Xiaoliang
Published: May 2023

To reveal the mechanical properties of rocks under stress disturbance and unloading confining pressure, conventional triaxial compression tests, triaxial compression tests on unloading damaged sandstone, and cyclic loading and unloading tests on unloading damaged sandstone were conducted. Then, the evolutionary characteristics of dissipated energy in sandstone under cyclic loading and unloading were explored, and damage variables were proposed. The crack development characteristics were analyzed from a microscopic perspective. The study results reveal that: (1) the sandstone exhibits obvious brittle failure under different stress paths, and the macroscopic failure mode is dominated by shear failure. As the number of cycles increases, the load-bearing capacity, elastic modulus, and deformation modulus of the sandstone will be significantly reduced if it suffers greater unloading damage. (2) The cyclic action in the early stage inhibits the development of the internal fracture. However, the inhibitory effect is significantly reduced for specimens with larger unloading quantities. The damage variable in the cyclic loading and unloading is about 50.00% of that in the unloading, indicating that unloading confining pressure is the dominant factor for specimen failure. (3) The extension of microcracks within the sandstone is dominated by intergranular cracks, and the number of cracks increases with the increase of unloading quantity. After cyclic loading and unloading, the structure becomes looser. The test results deepen the understanding of rock mechanical behavior and fracture evolution under cyclic loading and can provide a basis for structural stability improvement under stress disturbance and unloading confining pressure.
The potential role of pumpkin seeds oil on methotrexate-induced lung toxicity
Authors: Abosrea Aya M. , Aboul Ezz Heba S. , Mahmoud Sahar M. , Mousa Mohamed R. , Ahmed Nawal A.
Published: May 2023

Many chemotherapeutic drugs cause adverse pulmonary reactions leading to severe pulmonary disease. Though methotrexate (MTX) is used for the treatment of cancer and other diseases, it is highly toxic with multiple adverse effects including pulmonary toxicity. Essential oils represent an open frontier for pharmaceutical sciences due to their wide range of pharmacological properties. Pumpkin seeds oil (PSO) was used to investigate its ability to alleviate methotrexate-induced lung toxicity in rats. Lung tissue from MTX-treated group revealed a decrease in malondialdehyde, glutathione, and nitric oxide accompanied by a marked inhibition in cholinesterase activity, and enhanced catalase activity, tumor necrosis factor-α, interleukin-6 and vascular endothelial growth factor levels. Analysis of PSO revealed that the oil was rich in hexadecanoic acid, decane methyl esters, squalene, polydecane, docosane, and other derivatives. Administration of PSO ameliorated the oxidant/antioxidant and proinflammatory changes induced by MTX in the lung tissue. Histological examinations confirmed the potency of PSO in reducing the histopathological alterations induced by MTX. Immunohistochemical analysis showed decreased nuclear factor-kappa B and caspase 3 expression after PSO. The present data indicated the protective efficiency of PSO against MTX-induced lung injury by decreasing oxidative damage, inflammation and apoptosis and could thus be recommended as an adjuvant therapy.
A monopole antenna with cotton fabric material for wearable applications
Authors: Ayd R. Saad Ayman , Hassan Walaa M. , Ibrahim Ahmed A.
Published: May 2023

A monopole antenna operated at 2.45 GHz and embedded with artificial magnetic conductor (AMC) for wearable communication systems is investigated in this article. The proposed antenna is composed of a metalized loop radiator with a coplanar waveguide microstrip feedline which is affixed on a cotton fabric material substrate. As well, a cotton-based AMC surface is utilized to eliminate the body’s absorbed radiation and enhance the gain of the antenna. It is composed of 5 × 5 array unit cells etched with I-shaped slots. Using this configuration, simulations show that the specific absorption rate (SAR) level was significantly reduced. Considering flat and rounded body parts, it was found that the SAR values averaged over 10 g at a distance of 1 mm away from the tissues model were only 0.18 W/kg and 0.371 W/kg, respectively. Additionally, the antenna gain was improved up to 7.2 dBi with an average radiation efficiency of 72%. Detailed analysis with experimental measurements of the cotton-based antenna for different operation scenarios is introduced. The measured data show a good correlation with the electromagnetic simulation results.
In vitro and in vivo susceptibility to sulfadiazine and pyrimethamine of Toxoplasma gondii strains isolated from Brazilian free wild birds
Authors: de Lima Bessa Gabriella , Vitor Ricardo Wagner de Almeida , Lobo Luana Margarida Sabino , Rêgo Wagner Martins Fontes , de Souza Gabriela Carolina Alves , Lopes Rosálida Estevam Nazar , Costa Júlia Gatti Ladeia , Martins-Duarte Erica S.
Published: May 2023

Little is known about the existence of drug-resistantToxoplasma gondiistrains and their possible impact on clinic outcomes. To expand our knowledge about the existence of natural variations on drug susceptibility ofT. gondiistrains in Brazil, we evaluated the in vitro and in vivo susceptibility to sulfadiazine (SDZ) and pyrimethamine (PYR) of three atypical strains (Wild2, Wild3, and Wild4) isolated from free-living wild birds. In vitro susceptibility assay showed that the three strains were equally susceptible to SDZ and PYR but variations in the susceptibility were observed to SDZ plus PYR treatment. Variations in the proliferation rates in vitro and spontaneous conversion to bradyzoites were also accessed for all strains. Wild2 showed a lower cystogenesis capacity compared to Wild3 and Wild4. The in vivo analysis showed that while Wild3 was highly susceptible to all SDZ and PYR doses, and their combination, Wild2 and Wild4 showed low susceptibility to the lower doses of SDZ or PYR. Interestingly, Wild2 presented low susceptibility to the higher doses of SDZ, PYR and their combination. Our results suggest that the variability in treatment response byT. gondiiisolates could possibly be related not only to drug resistance but also to the strain cystogenesis capacity.
Association of cerebellar and pre-motor cortex gray matter density with subjective intoxication and subjective response following acute alcohol intake
Authors: Stennett-Blackmon Bethany A. , Sevel Landrew , Boissoneault Jeff
Published: May 2023

Acute alcohol intake produces subjective intoxication (SI) and response (SR; e.g., valanced stimulation and sedation), which has important implications for alcohol-related risk. Individuals who experience less SI may be more likely to engage in risky behaviors while drinking. Gray matter morphometry in brain regions underlying cognitive and affective processes may help to inform individual differences in subjective intoxication and response. The subjective effects of alcohol vary between limbs of the blood alcohol concentration (BAC) curve (i.e., whether BAC is rising or falling; acute tolerance). We examined the relationship between gray matter density (GMD) and SI/SR as a function of BAC limb. Healthy social drinkers (N = 89; 55 women) completed an alcohol challenge paradigm (target BAC = 0.08 g/dL) and structural magnetic resonance imaging (MRI). Participants completed measures of SR and SI on ascending and descending BAC limbs. Association between GMD and SI/SR on each limb were assessed using whole-brain, voxel-wise general linear models. GMD estimates were extracted from significant clusters. Differences in association of GMD and SI/SR between limbs were assessed using hierarchical regression. Significant associations of SI with GMD on the ascending limb were observed in the cerebellum. A significant association between SR and GMD on the descending limb were observed in the pre-motor cortex (BA6) and cerebellum. We identified common and unique associations among cerebellum and pre-central gyrus structures with SI and SR between BAC limbs. Functional imaging studies may further clarify unique dimensions of subjective alcohol effects linked to the observed structural associations.
Female scent accelerates growth of juvenile male mice
Authors: Zala Sarah M. , Church Brian , Potts Wayne K. , Knauer Felix , Penn Dustin J.
Published: May 2023

Exposing female house mice (Mus musculus) to male urinary scent accelerates their sexual development (Vandenbergh effect). Here, we tested whether exposing juvenile male mice to females’ urine similarly influences male growth and size of their sexual organs. We exposed three-week old male house mice to female urine or water (control) for ca. three months. We found that female-exposed males grew significantly faster and gained more body mass than controls, despite all males being reared on a controlled diet, but we detected no differences in males' muscle mass or sexual organs. In contrast, exposing juvenile males to male urine had no effect their growth. We tested whether the males' accelerated growth imposed functional trade-offs on males' immune resistance to an experimental infection. We challenged the same male subjects with an avirulent bacterial pathogen (Salmonella enterica), but found no evidence that faster growth impacted their bacterial clearance, body mass or survival during infection compared to controls. Our results provide the first evidence to our knowledge that juvenile male mice accelerate their growth when exposed to the urine of adult females, though we found no evidence that increased growth had negative trade-offs on immune resistance to infectious disease.
Metabolic profiles of lung adenocarcinoma via peripheral blood and diagnostic model construction
Authors: Kim Kyung Soo , Moon Seok Whan , Moon Mi Hyung , Hyun Kwan Yong , Kim Seung Joon , Kim Young Koon , Kim Kwang Youl , Jekarl Dong Wook , Oh Eun-Jee , Kim Yonggoo
Published: May 2023

The metabolic profile of cancerous cells is shifted to meet the cellular demand required for proliferation and growth. Here we show the features of cancer metabolic profiles using peripheral blood of healthy control subjects (n = 78) and lung adenocarcinoma (LUAD) patients (n = 64). Among 121 detected metabolites, diagnosis of LUAD is based on arginine, lysophosphatidylcholine-acyl (Lyso.PC.a) C16:0, and PC-diacyl (PC.aa) C38:3. Network analysis revealed that network heterogeneity, diameter, and shortest path were decreased in LUAD. On the contrary, these parameters were increased in advanced-stage compared to early-stage LUAD. Clustering coefficient, network density, and average degree were increased in LUAD compared to the healthy control, whereas these topologic parameters were decreased in advanced-stage compared to early-stage LUAD. Public LUAD data verified that the genes encoding enzymes for arginine (NOS, ARG, AZIN) and for Lyso.PC and PC (CHK, PCYT, LPCAT) were related with overall survival. Further studies are required to verify these results with larger samples and other histologic types of lung cancer.
Effects of rIL2/anti-IL2 antibody complex on chikungunya virus-induced chronic arthritis in a mouse model
Authors: Tritsch Sarah R. , Porzucek Abigail J. , Schwartz Arnold M. , Proctor Abigale M. , Amdur Richard L. , Latham Patricia S. , Simon Gary L. , Mores Christopher N. , Chang Aileen Y.
Published: May 2023

Chikungunya virus (CHIKV) is characterized by disabling joint pain that can cause persistent arthritis in approximately one-fourth of patients. Currently, no standard treatments are available for chronic CHIKV arthritis. Our preliminary data suggest that decreases in interleukin-2 (IL2) levels and regulatory T cell (Treg) function may play a role in CHIKV arthritis pathogenesis. Low-dose IL2-based therapies for autoimmune diseases have been shown to up-regulate Tregs, and complexing IL2 with anti-IL2 antibodies can prolong the half-life of IL2. A mouse model for post-CHIKV arthritis was used to test the effects of recombinant IL2 (rIL2), an anti-IL2 monoclonal antibody (mAb), and the complex on tarsal joint inflammation, peripheral IL2 levels, Tregs, CD4 + effector T cells (Teff), and histological disease scoring. The complex treatment resulted in the highest levels of IL2 and Tregs, but also increased Teffs, and therefore did not significantly reduce inflammation or disease scores. However, the antibody group, which had moderately increased levels of IL2 and activated Tregs, resulted in a decreased average disease score. These results suggest the rIL2/anti-IL2 complex stimulates both Tregs and Teffs in post-CHIKV arthritis, while the anti-IL2 mAb increases IL2 availability enough to shift the immune environment towards a tolerogenic one.
Evaluation of remote digital postoperative wound monitoring in routine surgical practice
Authors: McLean Kenneth A. , Sgrò Alessandro , Brown Leo R. , Buijs Louis F. , Daines Luke , Potter Mark A. , Bouamrane Matt-Mouley , Harrison Ewen M.
Published: May 2023

Remote digital postoperative wound monitoring provides an opportunity to strengthen postoperative community care and minimise the burden of surgical-site infection (SSI). This study aimed to pilot a remote digital postoperative wound monitoring service and evaluate the readiness for implementation in routine clinical practice. This was a single-arm pilot implementational study of remote digital postoperative wound monitoring across two tertiary care hospitals in the UK (IDEAL stage 2b, clinicaltrials.gov: NCT05069103). Adults undergoing abdominal surgery were recruited and received a smartphone-delivered wound assessment tool for 30-days postoperatively. Patients received 30-day postoperative follow-up, including the Telehealth Usability Questionnaire (TUQ). A thematic mixed-methods approach was used, according to the WHO framework for monitoring and evaluating digital health interventions. 200 patients were enroled, of whom 115 (57.5%) underwent emergency surgical procedures. Overall, the 30-day SSI rate was 16.5% (n = 33/200), with 72.7% (n = 24) diagnosed post-discharge. Usage of the intervention was 83.0% (n = 166/200), with subsequently 74.1% (n = 123/166) TUQ completion. There were no issues reported with feasibility of the technology, with the reliability (3.87, 95% CI: 3.73–4.00) and quality of the interface rated highly (4.18, 95%: 4.06–4.30). Patient acceptance was similarly high with regards to ease of use (4.51, 95% CI: 4.41–4.62), satisfaction (4.27, 95% CI: 4.13–4.41), and usefulness (4.07, 95% CI: 3.92–4.23). Despite the desire for more frequent and personalised interactions, the majority viewed the intervention as providing meaningful benefit over routine postoperative care. Remote digital postoperative wound monitoring successfully demonstrated readiness for implementation with regards to the technology, usability, and healthcare process improvement.
Distinct activation mechanisms regulate subtype selectivity of Cannabinoid receptors
Authors: Dutta Soumajit , Shukla Diwakar
Published: May 2023

Design of cannabinergic subtype selective ligands is challenging because of high sequence and structural similarities of cannabinoid receptors (CB1and CB2). We hypothesize that the subtype selectivity of designed selective ligands can be explained by the ligand binding to the conformationally distinct states between cannabinoid receptors. Analysis of ~ 700 μs of unbiased simulations using Markov state models and VAMPnets identifies the similarities and distinctions between the activation mechanism of both receptors. Structural and dynamic comparisons of metastable intermediate states allow us to observe the distinction in the binding pocket volume change during CB1and CB2activation. Docking analysis reveals that only a few of the intermediate metastable states of CB1show high affinity towards CB2selective agonists. In contrast, all the CB2metastable states show a similar affinity for these agonists. These results mechanistically explain the subtype selectivity of these agonists by deciphering the activation mechanism of cannabinoid receptors.
A Southern Ocean supergyre as a unifying dynamical framework identified by physics-informed machine learning
Authors: Sonnewald Maike , Reeve Krissy Anne , Lguensat Redouane
Published: May 2023

The Southern Ocean closes the global overturning circulation and is key to the regulation of carbon, heat, biological production, and sea level. However, the dynamics of the general circulation and upwelling pathways remain poorly understood. Here, a physics-informed unsupervised machine learning framework using principled constraints is used. A unifying framework is proposed invoking a semi-circumpolar supergyre south of the Antarctic circumpolar current: a massive series of leaking sub-gyres spanning the Weddell and Ross seas that are connected and maintained via rough topography that acts as scaffolding. The supergyre framework challenges the conventional view of having separate circulation structures in the Weddell and Ross seas and suggests that idealized models and zonally-averaged frameworks may be of limited utility for climate applications. Machine learning was used to reveal areas of coherent driving forces within a vorticity-based analysis. Predictions from the supergyre framework are supported by available observations and could aid observational and modelling efforts to study this climatologically key region undergoing rapid change.
Current advance of CRISPR/Cas-based SERS technology
Authors: Wang Huimin , Su Ailing , Chang Jingjing , Liu Xiangguo , Liang Chongyang , Xu Shuping
Published: May 2023

This review summarizes the applications of CRISPR/Cas technology combined with SERS for nucleic acid detection, the operation of CRISPR/Cas technology, elements of SERS sensors, and provides an outlook on future developments.
Scaling of the permanent electric dipole moment in isolated silicon clusters with near-spherical shape
Authors: Rivic Filip , Lehr Andreas , Schäfer Rolf
Published: May 2023

It is observed experimentally that the electric dipole moment of near-spherical SiN clusters with N = 30–90 increases almost linearly with cluster size which is attributed to different coordination numbers and partial charges of individual Si atoms.
Ionic and electronic polarization effects in horizontal hybrid perovskite device structures close to equilibrium
Authors: Moia Davide , Jung Mina , Wang Ya-Ru , Maier Joachim
Published: May 2023

Mixed ionic–electronic conduction and space-charge polarization determine the electrical response of MAPbl3-based horizondal devices close to equilibrium.
The development history and evolutionary trends of percarbonate: Bibliometric analysis from 2000 to 2022
Authors: Xue Honghai , Li Jinying , Zhang Genbao , Liu Binshuo , Li Ming , Wang Hongliang
Published: May 2023

This work presents the first bibliometric analysis of 258 papers on percarbonate from 2000 to 2022. The research hotspots and trends of percarbonate research were analyzed and the challenges and prospects of percarbonate research were put forward.
Real-time thermal decomposition kinetics of GaAs nanowires and their crystal polytypes on the atomic scale
Authors: Schmiedeke Paul , Panciera Federico , Harmand Jean-Christophe , Travers Laurent , Koblmüller Gregor
Published: May 2023

Thermal decomposition of GaAs nanowires is investigated. Radially it is faster for zinc-blende, due to nano-faceted sidewalls. In contrast, wurtzite forms stable single-faceted sidewalls with decomposition only via step-flow from the tip.
Optimization and characterization of miRNA-129-5p-encapsulated poly (lactic-co-glycolic acid) nanoparticles to reprogram activated microglia
Authors: Kalashnikova Irina , Cambell Heather , Kolpek Daniel , Park Jonghyuck
Published: May 2023

Polymer based nanoparticle-mediated miRNA-129-5p delivery can reprogram activated microglia to limit inflammatory responses.
Preparation and antibacterial study of waterborne polyurethane modified with lysine and quaternary ammonium salt
Authors: Xu Mengting , Wang Yu , Shi Jichao , Wu Dandan , Lin Lin , Jia Runping , Zhai Yinghao , Qian Hongxiang
Published: May 2023

The “1 + 1 > 2” synergistic antibacterial system significantly enhanced synergistic antibacterial performance, and the antibacterial efficiency against E. coli and S. aureus increases by 15% and 4.2%, respectively.
A quasi-solid polymer electrolyte initiated by two-dimensional functional nanosheets for stable lithium metal batteries
Authors: Zhang Ying , Huang Jiawen , Wang Guanyao , Dou Yuhai , Yuan Ding , Lin Liangxu , Wu Kuan , Liu Hua Kun , Dou Shi-Xue , Wu Chao
Published: May 2023

Lithium-metal batteries (LMBs) are expected to serve as next-generation energy storage systems due to their high theoretical energy density.
Preferred catalysis distinctly determined by metals doped with nitrogen in three-dimensionally ordered porous carbon materials
Authors: Maruyama Jun , Sato Hirohumi , Takao Yuko , Maruyama Shohei , Kato Shintaro , Kamiya Kazuhide , Chida Koki , Yoshii Takeharu , Nishihara Hirotomo , Tani Fumito
Published: May 2023

Carbon materials with 3D-ordered nanopores doped with metals and nitrogen were synthesized from strategically designed phthalocyaninesviathe self-assembly of Fe3O4nanoparticles. Their catalytic activity was determined by the doped metals.
DNA-caged nanoparticles via electrostatic self-assembly
Authors: Jergens Elizabeth , de Araujo Fernandes-Junior Silvio , Cui Yixiao , Robbins Ariel , Castro Carlos E. , Poirier Michael G. , Gurcan Metin N. , Otero Jose J. , Winter Jessica O.
Published: May 2023

Top: Schematic of DNA-caged nanoparticle composite formation. Bottom: U87 cells labeled with fluorescent DNA-caged nanoparticles before and after erasing with single stranded DNA. Scale bar = 10 μm.
A honeycomb carbon substrate anchored with Sn and Sb bimetallic atoms boosts oxygen-reduction electrocatalysis
Authors: Li Shuting , Han Jinxi , Guo Yuyu , Xia Zhengqiang , Chen Sanping , Xie Gang , Gao Shengli , Yang Qi
Published: May 2023

The electrocatalyst prepared by anchoring Sn and Sb on honeycomb carbon substrate with large specific surface area has excellent ORR performance and high stability. Zinc-air battery based on the catalyst can run stably for more than 1100 hours.
Mechanistic understanding of the dual gold and photoredox-catalyzed thiosulfonylation of alkynes and enynes: a DFT study
Authors: Wang Kaifeng , Bao Xiaoguang
Published: May 2023

The detailed mechanisms of dual gold and photoredox-catalyzed thiosulfonylation of alkynes and 1,6-enynes with PhSO2SCF3 were explored via DFT calculations.
A rational strategy for substantially enhancing the solar-utilization efficiency and organic-pollutant-degradation rate via mediated central processing unit filling
Authors: Li Nana , Wang Baohui , Wang Meng , Tao Lei , Li Chaoying , Qiao Zhiqiang , Gu Di , Zhu Lingyue , Yuan Dandan , Wu Hongjun , Wang Xirui
Published: May 2023

Hybrid strategy of utilizing large solar thermal input overlaid with solar electricity for continuous wastewater purification without any catalyst.
Redox-active oxygen in oxides: emergent applications, including field-induced resistive switching, flash luminescence, p–n junctions and high capacity battery cathodes
Authors: West Anthony R.
Published: May 2023

Oxide ions are traditionally regarded as forming the inert anion sub-lattice of oxide structures whose properties are largely dominated by the cations present.
Optimal consensus control for multi‐agent systems: Multi‐step policy gradient adaptive dynamic programming method
Authors: Ji Lianghao , Jian Kai , Zhang Cuijuan , Yang Shasha , Guo Xing , Li Huaqing
Published: May 2023

This paper presents a novel adaptive dynamic programming (ADP) method to solve the optimal consensus problem for a class of discrete‐time multi‐agent systems with completely unknown dynamics. Different from the classical RL‐based optimal control algorithms based on one‐step temporal difference method, a multi‐step‐based (also call n‐step) policy gradient ADP (MS‐PGADP) algorithm, which have been proved to be more efficient owing to its faster propagation of the reward, is proposed to obtain the iterative control policies. Moreover, a novel Q‐function is defined, which estimates the performance of performing an action in the current state. Then, through the Lyapunov stability theorem and functional analysis, the proof of optimality of the performance index function is given and the stability of the error system is also proved. Furthermore, the actor‐critic neural networks are used to implement the proposed method. Inspired by deep Q network, the target network is also introduced to guarantee the stability of NNs in the process of training. Finally, two simulations are conducted to verify the effectiveness of the proposed algorithm.
Fault‐tolerant fixed‐time prescribed performance control of MEMS gyroscope
Authors: Esmaeili Seyed Mohammadreza , Zahedifar Rasoul , Keymasi‐Khalaji Ali
Published: May 2023

This paper investigates a fault‐tolerant fixed‐time prescribed performance microelectromechanical system gyroscope using the adaptive backstepping method. The control protocol is designed such that not only is the system robust to even extremely harsh conditions of disturbance and actuator faults but also the performance and its settling time are user‐adjustable. Also, the system itself along with the external disturbances and actuator faults are assumed to be uncertain. Two case studies have been analyzed; the controller performance in the presence of very severe while uncertain disturbance and actuator faults, and a comparison between fixed‐time and finite‐time in this model in terms of their performance and convergence rate. First, the dynamics of the system are derived, and the prescribed performance error is defined for the analysis. Then, using the backstepping method, and adaptive estimations for the uncertainties, the algorithm is designed to converge the errors to a small set near zero with a fixed‐time convergence rate after which the stability of the system is verified via Lyapunov theory. In the end, a simulation example is presented in each case study to represent the efficacy of the proposed control scheme.
Dual‐stage day‐ahead optimized performance of renewable‐based microgrids
Authors: Helmi Ahmed M. , Abo‐Elyousr Farag K. , Haes Alhelou Hassan , Ramadan Haitham S.
Published: May 2023

In distributed networks, wind turbine generators (WTGs) are to be optimally sized and positioned for cost‐effective and efficient network service. Various meta‐heuristic algorithms have been proposed to allocate WTGs within microgrids. However, the ability of these optimizers might not be guaranteed with uncertainty loads and wind generations. This paper presents novel meta‐heuristic optimizers to mitigate extreme voltage drops and the total costs associated with WTGs allocation within microgrids. Arithmetic optimization algorithm (AOA), coronavirus herd immunity optimizer, and chimp optimization algorithm (ChOA) are proposed to manipulate these aspects. The trialed optimizers are developed and analyzed via Matlab, and fair comparison with the grey wolf optimization, particle swarm optimization, and the mature genetic algorithm are introduced. Numerical results for a large‐scale 295‐bus system (composed of IEEE 141‐bus, IEEE 85‐bus, IEEE 69‐bus subsystems) results illustrate the AOA and the ChOA outperform the other optimizers in terms of satisfying the objective functions, convergence, and execution time. The voltage profile is substantially improved at all buses with the penetration of the WTG with satisfactory power losses through the transmission lines. Day‐ahead is considered generic and efficient in terms of total costs. The AOA records costs of 16.575M$/year with a reduction of 31% compared to particle swarm optimization.
On the creative teaching in primary school music classroom
Authors: Xue Mengyuan , Xian Yingying
Published: May 2023

Music creative teaching has a positive influence on developing students 'consciousness of music creation, students' creative thinking and cultivating innovative practice ability. This paper focuses on the connotation and significance of primary school music creation teaching, analyzes the factors affecting the creation of teaching in primary school classroom, and puts forward suggestions for teaching implementation. It aims to develop students' creative potential and enhance their creativity, hoping to provide a new perspective for relevant research fields and contribute to the cultivation of innovative talents in the new era of the 21st century.
A useful method for postgraduate of chemical engineering in understanding the public opinions of public events related to their major: A case study of health communication and public opinions of COVID-19 on Twitter in Germany
Authors: Zhao Ningning , Yu Xiaojiao , Zhang Zhicheng , Yu Zhong , Yao Binghua , Niu Jinfen , Liu Nailiang , Li Junpeng
Published: May 2023

In order to adapt to the latest development of higher education in the era of big data, improve the sensitivity for postgraduate of chemical engineering in the public opinions of public events related to their major, this study took “the pandemic of COVID-19 on Twitter in Germany” as an example and investigated the health communication and public opinions on COVID-19 based on the Python scripts and Twitter streaming application programming interface using statistical analysis and chi square feature selection. The provided method is helpful to improve the insight, prediction, scientific literacy and innovation ability of postgraduate of chemical engineering.
Construction and exploration of practical education system of applied chemistry under the background of new engineering
Authors: Yu Xiaojiao , Wei Yuchen , Zhao Ningning , Liu Zongbin , Niu Jinfen , Yu Zhong , Liu Nailiang , Liu Guangjun , Zhang Jian
Published: May 2023

Chemistry is an experimental science. Practical teaching is a significant link in the cultivation of students majoring in chemistry to foster students' practical, professional application, and innovation abilities. Based on the investigation and analysis of the problems existing in the cultivation of the practical ability of applied chemistry major, take specific measures, such as constructing the practical teaching system of applied chemistry major, explored a better practical teaching system for students of applied chemistry major; applied to the reform and innovation of training mode of students majoring in applied chemistry and achieved good results.
Exploration on the cultivation of innovative talents in the course of chemistry teaching
Authors: Liu Nailiang , Li Shasha , Li Junpeng , Zhao Ningning , Yu Zhong
Published: May 2023

Cultivating innovative talents to meet the needs of professional development is an urgent mission of higher education institutions under the situation of “Double First-Class” construction. As one of the foundations of science and technology major, chemistry courses play an essential role in promoting an innovative spirit, cultivating creative consciousness, and improving creative ability. This paper discussed the optimization of the curriculum system, the construction of the teaching mode, and the transformation of the cultivation mode of chemistry courses in engineering majors from the aspects of curriculum design, theoretical teaching, experimental teaching, and out-of-class training. Through cultivating innovation consciousness in theory and experimental teaching, and improving innovation ability in extra-curricular practical education, we hope to bring a positive effect on the reform of the cultivation mode of innovation ability in the teaching process of chemistry courses in engineering colleges and universities.
An optimization scheme of partial total homomorphic encryption
Authors: Luo Guangqiao , Zhao Haijun , Chen Huayue
Published: May 2023

In order to further improve the effectiveness of homomorphic cryptography, we optimize Lauter et al. 's partial homomorphic cryptography scheme, and propose a new RLWE-based total homomorphic cryptography (FHE) scheme, which combines a series of existing techniques with the Chinese residual theory, and merges several “plaintext slots” into a ciphertext for homomorphic computation. The extended key transformation technology and modulo transformation technology are used to reduce the noise of ciphertext and enable it to carry out the next homomorphic operation. Compared with the original scheme, the security and effectiveness of the scheme were studied on the premise of ensuring CPA security, and the results showed that the performance of the scheme was improved by N times.
Research on the problems and paths of higher vocational school-enterprise cooperation education in the new era
Authors: Li Guangyan , Gu Cuihong
Published: May 2023

School-enterprise cooperation education plays a huge role in serving the people's livelihood, optimizing the talent supply structure, and promoting the transformation of type education. Facing the new challenges brought by the sharp increase in enrollment, the diversification of student source structure, the shortage of educational resources and the reform of teaching methods under the background of enrollment expansion, higher vocational colleges need to establish quality development based on the innovation of talent training mode, the sharing of educational and teaching resources and the quality of teaching management. Under the guidance of these objectives, we should emphasize the people-oriented values, the concept of ability first and the concept of quality first, so as to optimize the practice ecology of school-enterprise cooperation education, promote the connotation development of higher vocational education and the sustainable development of social economy.
Innovation and practice of production-education integration in private higher education under the background of new engineering
Authors: Wang Mengxia
Published: May 2023

The integration of production and education plays an important role in the cultivation of talents in higher engineering education. By reading literature, this paper studies the current situation of the development of production-education fusion of private higher education under the background of new engineering, analyzes its achievements and problems in the aspect of production-education fusion of private higher education. Based on the requirements of new engineering and private education, this paper puts forward the construction of a model fitting the actual situation of our country. From the education goal, training content,
Exploration and practice of aviation manufacturing talent training mode based on “practical ability-oriented and industry-education integration”
Authors: Hu Zheng , Sun Shiping , Cheng Lan
Published: May 2023

The aviation manufacturing industry is a key area for innovation-driven development. In order to adapt to the new requirements for aviation manufacturing talents put forward by the transformation and upgrading of the aviation industry, Nanchang Hangkong University and AVIC Hongdu Group continue to explore and practice the talent training channels urgently needed for tooling design positions. The university and enterprise jointly built an aviation manufacturing talent training model based on “practical ability-oriented and industry-education integration.” The effective method formed from four aspects: the determination of talent training methods, the establishment of professional curriculum system, the innovation of teaching methods and the improvement of university-enterprise collaborative management mechanism. Thus, the win-win cooperation between the university and enterprise has been realized, and valuable experience has been accumulated for exploring a new aviation manufacturing talent training model.
Multimodal discourse analysis of the external publicity documentary four seasons of China
Authors: Lv Jiaxin
Published: May 2023

As one of the effective forms of cultural exchange between China and foreign countries and the shaping of national image abroad, the external publicity function of documentaries has been increasing. The paper argues that the mutually reinforcing relationship between the images and text modes in the documentary objectively conveys to foreign audiences that China upholds the ecological concept of caring for nature and advocating the harmonious coexistence between man and nature. Meanwhile, the paper finds that the image of a big country has been established, including the image of respecting nature, adapting to nature, and protecting nature in the Four Seasons of China. The implications of this study are relevant for proposing an MDA framework for external publicity documentaries from the cultural, context, content, and expression levels, to explore the multimodal strategy of external publicity documentaries to help China project a good national image internationally.
Research on curriculum ideological and political design based on online and offline mixed teaching
Authors: Cheng Yulong
Published: May 2023

"Curriculum ideological and political education" is to integrate ideological and political education elements into professional courses, imperceptibly influence students' ideology and behavior, and give full play to the function of cultivating virtues and cultivating people. This paper explores ideological and political elements deeply, according to the requirements of curriculum standards, centering on teaching objectives and teaching content, carries out curriculum ideological and political design based on blended teaching mode, runs ideological and political education throughout education and teaching, implements the goal of "three-in-one education", and cultivates students' good professional quality and professional skills.
Teaching reform and practice of database principle and application
Authors: Li Junshan , Hu Yi
Published: May 2023

Aiming at the characteristics that the content of database principles and applications is difficult to understand and master, this paper first analyzes the comprehensive and practical characteristics of database principle and application course, and then systematically introduces some innovative practices of the author in textbook construction, teaching content reform and design ability training, including the construction of systematic case teaching content system; The reform of curriculum content system keeping pace with the times; The construction of innovative design ability training system; The practice of curriculum design that is closely integrated with application; The introduction of typical entrepreneurial innovation cases; The guidance of famous sayings and aphorisms compatible with the curriculum. The author's beneficial attempts and innovative practices in the construction of database principle and application courses and the training of applied computer talents are expected to play a certain enlightening role in the teaching of computer majors, teachers and courses in relevant colleges and universities.
On the construction of characteristic specialty of the local applied undergraduate for the talent training of new engineering course
Authors: Ji Tian , Jia Xiuhan , Pang Guibing
Published: May 2023

Combine the requirements of new engineering construction and required by China 2025 for professional personnel training, and meet the industry's demand for high-quality technical personnel. This paper takes the mechanical major as an example, puts forward the construction of characteristic specialty for the construction of new engineering course. Reforming the original talent training mode, strengthening the training of engineering application ability and innovative practice ability, and building a characteristic professional teaching and practice system that meets the needs of enterprises and serves local industries. Throughout the project teaching method and the whole teaching process, which is based on engineering practice education center, furthermore, it deepen cooperation between colleges and enterprises, production and education integration, which establishing an all-round quality guarantee and monitoring system. And it cultivates application-oriented engineering practice and innovation ability of the foundation.
The practical teaching design of illustration design course based on OBE concept
Authors: Chen Yanfei , Lu Zhijie
Published: May 2023

Based on the concept of OBE education and taking the course of Illustration Design as an example, this paper expounds in detail how to apply the concept of OBE to practice teaching design by focusing on teaching objectives, teaching contents, teaching methods, teaching modes, teaching resources, course assessment and achievement evaluation. This can be used for reference to solve the problems existing in the course teaching and effectively improve the quality of the course teaching.
Research on the teaching reform of the course web front-end design based on the emerging engineering education model
Authors: Wang Xiaosong
Published: May 2023

Web Front-end Design is a basic professional course of information management and information system major. The course mainly trains students' ability of web design and website development. This paper attempts to change the traditional teaching mode that teachers are the main body. It tries to build a new teaching mode that students are the main body and teachers are the guiders. In the process of curriculum reform, the complete project-driven teaching method is adopted to complete the teaching of course knowledge points. At the same time, the reform references to the emerging engineering education model with the whole life cycle of the system's conceive, design, implement and operate (CDIO) as the background. By the reform, students can change passive learning into active learning, improve their practical ability, and further enhance the practical development ability of Web page design projects.
An empirical study of the factors affecting moral hazard for doctors based on fraud theory
Authors: Wang Yaohui , Chen Tongxian , Chen Xiaohan
Published: May 2023

Doctor moral hazard behavior is a topical and sensitive issue in medicine. Recognition of the factors that influence doctor moral hazard behavior is fundamental to controlling or preventing it. Researchers have identified the factors that influence doctor moral hazard behavior based on models of fraud risk. In this present study, these factors were categorized into five dimensions: motivation, opportunity, rationalization, exposure, and punishment. A literature review and in-depth interviews with experts led to the development of a scale of the factors that affect doctor moral hazard. The scale has good reliability and validity. Data were obtained by interviewing medical staff. By using IBM SPSS 20.0 and AMOS 20.0, nine factors with strong explanatory power were extracted: economic pressure, pressure to undertake scientific research, decision-making autonomy, patient participation, treatment uncertainty, systemic deficiencies, probability of exposure, threat of hospital punishment, and threat of social punishment. The development of the scale and the extraction of the key influencing factors clarified the scope and the nature of factors that influence doctor moral hazard behavior. The analysis also provides a basis for governments and hospitals to govern doctor moral hazard behavior.
Research on reform of practical teaching system for applied undergraduate engineering students
Authors: Wei Zhongju , Yu Fangfang , Xie Xiaoping
Published: May 2023

In response to the low quality of practical teaching in engineering majors, particularly in terms of the effectiveness of experimental teaching, lack of innovation, and other issues, this paper summarizes and analyzes the problems that exist in experimental teaching and innovative practices for cultivating applied undergraduate students, based on the requirements for graduate abilities and knowledge from corporate employers, as well as the situation of engineering practical teaching in China. It explores the composition of various elements in the practical teaching system, standardizes and innovates various elements of experimental teaching activities, and cultivates students' innovative thinking and practical abilities through a multilevel disciplinary competition system, thus constructing an innovative practical teaching system for cultivating applied undergraduate students. The practice has proved that students' practical and innovative abilities are significantly enhanced, their innovative abilities are significantly improved, the quality of graduates' employment is improved, and the social feedback is positive. A large number of high-quality applied undergraduate students have been cultivated for local economic construction.
Practice OBE concept and innovate the guidance method for graduation design of electrical engineering
Authors: Meng Xiaofang , Wang Lidi , Tian Youwen , Zhang Nannan , Wang Hui
Published: May 2023

In order to improve the quality of undergraduate graduation design, this paper studies and improves the guidance method of electrical engineering graduation design based on the OBE concept. The graduation design teaching process was discussed around the topic selection stage, the topic opening stage, and the design stage. The main goal is to expand students' knowledge, enhance their engineering knowledge and improve their ability to solve practical engineering problems. The process inspection and guidance methods were optimized from the three levels of instructors, majors and colleges. The process inspection and guidance of colleges and specialties were online or offline. After the student selected the topic, the graduation design guidance and inspection of the instructor was conducted face to face or online. Through the questionnaire survey, this paper completed the achievement degree analysis of graduation design goals. The method proposed in this paper is beneficial to improving the practical ability and innovation ability of electrical engineering undergraduates.
Exploration and research on transforming the traditional working methods of college student affairs in the post epidemic era
Authors: Xu Yimeng , Zhang Chunjing , Wang Yan , Li Dongdong , Guo Jiawei , Li Ruchao , Nao Siwei
Published: May 2023

In the post epidemic era, although the COVID-19 epidemic is becoming stable under the strong control of the country, the complexity of the COVID-19 epidemic situation has brought great impact on the life and learning of college students. Therefore, the work of counselors is also facing great challenges in the post epidemic era today. The sudden COVID-19 epidemic has changed the actual work situation of college counselors. The work object requires refinement from face to point, the work position impacts the traditional mode from offline to online, and the difficulties in work face problems and contradictions. Faced with such a situation, college counselors need to change their work strategies, improve their work efficiency, study and judge the corresponding methods of emergencies, emphasize professional and role positioning and subdivide their work responsibilities, adhere to the fundamental and strengthen the ideological guidance in special periods. At present, college counselors should cultivate their internal skills, firm their beliefs, keep the "unchanged" and lead the "change". Through a comprehensive discussion on the work challenges faced by counselors during the COVID-19 epidemic and the main problems of college students, new ideas are provided for the work of counselors in the "post epidemic era".