bluuebunny/crossref_metadata_2025 huggingface dataset:
Asociación entre variantes alélicas de la familia de genes relacionados con la acción de FGF21 y niveles plasmáticos de adiponectina en edad prepuberal
Authors:   ,   Pontificia Universidad Católica de Chile. Facultad de Medicina, Guzmán Montenegro Eghon Enrique
Published: April 2023

El Factor de crecimiento de fibroblastos-21 (FGF21) y la adiponectina son dos importantes hormonas secretadas por el hígado y el tejido adiposo respectivamente. Estudios en animales de experimentación han propuesto que los efectos beneficiosos de FGF21 sobre la sensibilidad a la insulina están mediados por la adiponectina a través del eje FGF21-adiponectina. Mediante este eje, FGF21 promueve la síntesis y secreción de adiponectina. Variantes genéticas de FGF21 han sido asociadas previamente con variables cardiometabólicas y patrones de ingesta. Objetivo: Evaluar la asociación entre variantes alélicas de la familia de genes relacionados con la acción de FGF21 y los niveles plasmáticos de adiponectina en la edad prepuberal. Sujetos y Método: Estudio transversal de n=750 niños (Edad: 6.8 ± 0.44 años; 50,7% niñas), basado en la cohorte chilena de base poblacional “Estudio de Crecimiento y Obesidad” (ECO). A partir del microarreglo de genotipado masivo MEGA-Illumina, se determinaron los genotipos de 12 variantes de FGF21, 16 variantes del receptor FGFR1, 52 variantes de FGFR2, 3 variantes de FGFR3 y 17 variantes del co-receptor β-klotho (KLB). Las mediciones de adiponectina plasmática se realizaron mediante inmunoensayos. Las asociaciones entre variables se evaluaron mediante regresión lineal múltiple ajustando por edad, sexo, z-score de IMC y componentes principales indicadores de etnia. Resultados: Solamente una variante de KLB (rs80014142) y dos variantes de FGFR2 (rs3135808 y rs10510096) mostraron asociaciones nominalmente significativas con los niveles plasmáticos de adiponectina en niños de edad prepuberal (valores p de 0.006, 0.01 y 0.03 respectivamente). Ninguna de las tres variantes genéticas encontradas alcanzó significación tras corrección por comparaciones múltiples. Únicamente la variante rs80014142 se asoció significativamente con la razón leptina/adiponectina plasmática (p=0.003), que es considerado como un subrogado de resistencia a la insulina. Ninguna de estas variantes se asoció significativamente con el índice HOMA-IR. Conclusión: Es improbable que las variantes alélicas de la familia de genes relacionados con la acción de FGF21 tengan un impacto relevante en los niveles de adiponectina plasmática en edad prepuberal.
Competencia cultural en los egresados de odontología de un programa universitario en Chile
Authors:   ,   Pontificia Universidad Católica de Chile. Facultad de Medicina, Fredes Ziliani Amanda
Published: April 2023

Introducción: Competencia Cultural (CC) en salud es el constructo entendido como la habilidad de los profesionales de salud para reflexionar sobre su propia cultura e incorporar una visión social y cultural en cada interacción con el usuario. La CC posee múltiples dimensiones, tales como sensibilidad, habilidades y conocimientos y a su vez multiniveles. Es decir, involucra tanto a sistemas de salud, profesionales y usuarios. En Chile, no existe información sobre la CC en odontólogos. El objetivo de este trabajo fue evaluar la CC de los egresados de odontología de un programa universitario de Chile. Metodología: Estudio analítico de corte transversal. Se aplicó una encuesta online que incluía dos ítems. El primero, la escala validada para profesionales de la salud (ECCM-14). El segundo ítem, 9 preguntas de contexto sociodemográfico y laboral. Los participantes fueron egresados desde el 2015 hasta el 2020 e internos del año 2020 de odontología de la Pontifica Universidad Católica de Chile. Resultados: La tasa de respuesta fue de un 56%. Odontólogos e internos obtuvieron un puntaje de CC de 80.0. Discusión: En la subdimensión habilidades se obtuvo el puntaje más bajo con una mediana de 75 puntos, esto podría deberse a la ausencia de formación en relación a cómo adaptar estrategias de salud a los diferentes usuarios y contextos culturales. Conclusión: Este es el primer estudio de odontólogos y CC en Chile, se debe incluir a esta población del equipo de salud en próximas mediciones e investigaciones en CC. El nivel de CC es mayor en relación con estudios realizados previamente.
Modeling and simulation of the furniture manufacturing and assembly process in the arena simulation software
Authors:   University of Bielsko-Biala, Kolny Damian , Kaczmar-Kolny Ewa , Dulina Ľuboslav
Published: April 2023

The article describes issues related to creating discrete simulation models for the implementation of the furniture manufacturing and assembly process in a furniture company. The methodology of the manufacturing system analysis was presented, which is aimed to support the appropriate approach to the construction of simulation models. The scope of the work includes the technological identification of the furniture manufacturing and assembly process in real production conditions, on the basis of which the appropriate simulation model was built. The course of the process was analyzed in the Arena software on the basis of a computer simulation based on reports. As a result of the simulation of the manufacturing process with the use of information from report of usage, an area for improvement was located. The re-analysis of the material flow made it possible to propose a change in the input parameters for the simulation model in the indicated area. The results of the second simulation show significant changes in the effective use of workstations and increase in the efficiency of the production line. In practice, it can be the basis for introducing simulated changes in the production system.
Juventude quilombola e associativismo na Amazônia
Authors: Medeiros Monique , De Siqueira Patrícia Benedita Leão , Tecchio Andréia
Published: April 2023

As organizações sociais são de fundamental importância para o desenvolvimento rural, pois contribuem para melhorar a qualidade de vida da sociedade e oportunizam a geração de emprego e renda, o acesso à saúde, à educação e ao lazer. Este trabalho teve por objetivo analisar como se constrói a relação da juventude rural da comunidade de Porto Alegre com a Associação de Remanescentes de Quilombo de Porto Alegre (ARQUIPA), sediada no município de Cametá, PA. A pesquisa foi desenvolvida no período de agosto de 2018 a junho de 2019 e caracteriza-se como estudo de caso. O público alvo foi composto por integrantes da comunidade e os procedimentos metodológicos utilizados no desenvolvimento da pesquisa incluem a Matriz SWOT, entrevistas semiestruturadas, análise documental com foco principal nos documentos que regem ARQUIPA, e pesquisas bibliográficas. As análises realizadas indicam que a participação da juventude de Porto Alegre na ARQUIPA ainda é incipiente. A principal razão identificada diz respeito às diferenças de perspectivas acerca de organização social entre os jovens da comunidade e os membros não jovens da Associação. No entanto, sujeitos pertencentes aos dois grupos têm buscado sanar essas dificuldades, o que propicia um horizonte de perspectivas.
Planejamento urbano e gestão socioambiental na cidade de Marabá/PA
Authors: Silva Julyana Carvalho Kluck , Morales Gundisalvo Piratoba , Pontes Altem Nascimento
Published: April 2023

O presente artigo teve como objetivo analisar e discutir a aplicabilidade da Lei Nº 17.846/2018, de 29 de março de 2018, que descreve a revisão do plano diretor participativo do município de Marabá, Pará, e outras providências, como principal instrumento para a estruturação urbana e gestão socioambiental. O estudo foi realizado a partir da análise documental do plano diretor de Marabá e dos dados provenientes do IBGE, SNIS, ABES, CNES, Ministério da Saúde, INEP, IDEB, INPE. A tabulação dos dados foi realizada através do programa Excel 2016 e os mapas foram elaborados por meio dos programas ArcGIS e QGIS. Os resultados indicaram que o plano diretor não está sendo utilizado como instrumento de planejamento municipal e orientação referente à gestão socioambiental. Além disso, caracteriza-se por possuir diversas inconsistências em sua aplicabilidade no município de Marabá, frente às responsabilidades com a sociedade e o meio ambiente e a sua importância como norteador para a construção de uma cidade sustentável.
Suicidality in Rural Communities: A Scoping Review of Research in Canada
Authors: Rauch Kyrra , Ryan Kim , Ramsey Doug , Epp Donna , Lee Stacey , Herron Rachel , Mullins Sharran , Thomson Andrea E. , Waddell-Henowitch Candice
Published: April 2023

A scoping review of research about suicidality in rural and remote Canadian communities, published between 2009 and July 2020 was conducted by searching Embase, Medline, CINAHL, PsychInfo, SocIndex, Geobase, and PsycArticles databases. Included articles were reviewed and charted using data extraction. Thirty-nine Canadian, non-Indigenous articles met inclusion. Most publications were based on quantitative research (23). Apart from one intervention study, articles were prevention focused, with suicidality risk and protective factors noted to be of particular interests. The most frequently referenced suicidality risk factor was rural residence. It is anticipated that results of this review will inform future research, particularly the need to include qualitative and mixed methodologies, protocol, and evaluations of interventions as well as postvention research, with further consideration of different Canadian settings and populations.
Effect of Pre-harvest Salicylic Acid Spray on Shelf Life and Biochemical Changes of Litchi during Storage
Authors: Kumari Priti , Kumar Pawan , Karuna Kumari , Aftab Ahmar , Kumar Anand , Ahmad Feza
Published: April 2023

An experiment was conducted on litchi cv. China at Horticulture garden in the Department of Horticulture (Fruit and Fruit Technology), Bihar Agricultural University, Sabour, Bhagalpur, Bihar, to show the shelf life and biochemical changes of litchi during storage. The experiment was laid out in randomized block design with five treatments and four replications. Salicylic acid was sprayed twice i.e. 15 days and 30 days before anticipated harvesting time with different concentrations of salicylic acid (T1- 50 ppm, T2-100 ppm, T3-150 ppm, T4-200 ppm and T5-control). Different concentrations have different effect on shelf life and biochemical parameters. Salicylic acid with T3-150 ppm has increased TSS (20.02 0Brix), total sugar (13.10%), ascorbic acid (38.21 mg/100 g pulp), anthocyanin (8.06 mg/100g pulp) and shelf life (4 days) on the 6th day of storage at ambient condition.
Patterns in Location of Death From Firearm Injury in the US
Authors: Agoubi Lauren L. , Duan Ning , Rowhani-Rahbar Ali , Nehra Deepika , Sakran Joseph V. , Rivara Frederick P.
Published: April 2023

This cross-sectional study assesses non–self-inflicted firearm-related deaths occurring at inpatient or outpatient facilities, hospice care, nursing homes, home, or other settings from 1999 to 2021.
Good Bye, Liberal-Legal Democracy!
Authors: de Sa e Silva Fabio
Published: April 2023

Every other day, books and articles are published that examine the withering of democracy across multiple national contexts, perhaps best summarized by Steven Levitsky and Daniel Zibblat’s How Democracies Die. The law has not been ignored in this burgeoning literature. Telling examples are the studies on autocratic legalism by Javier Corrales and Kim Lane Scheppele; Tom Ginsburg and Aziz Huq’s book How to Save a Constitutional Democracy; a recent review essay by Michael McCann and Filiz Kahraman on the “interdependence of liberal and illiberal legal orders … in the United States”; and two forthcoming works from the Project on Autocratic Legalism: a special issue in the Verfassung und Recht in Übersee/World Comparative Law journal and a book on Brazil edited by Oscar Vilhena Vieira and colleagues. In this review essay, I focus on three critical issues arising from these and other sources. First, they show that a backlash against liberal democracies is happening in both the global South and the global North. Second, they show that law is no longer thought of as an intrinsic bulwark against assaults on liberal democracy—on the contrary, rising autocrats, many of whom are trained lawyers, often use the law as a tool to consolidate power, sideline minorities and political adversaries, and rule unconstrained. Finally, while earlier analyses of this phenomenon have tended to emphasize legislative change that reconfigured governance at its highest levels (the Presidency or Prime Minister’s Office, Congress, and High Courts), new studies are revealing––and are helping constitute––an empirically broader field of inquiry.
Iterative roots of two-dimensional mappings
Authors: Yu Zhiheng , Li Lin , Matkowski Janusz
Published: April 2023

As a weak version of embedding flow, the problem of iterative roots is studied extensively in one dimension, especially in monotone case. There are few results in high dimensions because the constructive method dealing with monotone mappings is unavailable. In this paper, by introducing a kind of partial order, we define the monotonicity for two-dimensional mappings and then present some results on the existence of iterative roots for linear mappings, triangle-type mappings, and co-triangle-type mappings, respectively. Our theorems show that even the property of monotonicity for iterative roots of monotone mappings, which is a trivial result in one dimension, does not hold anymore in high dimensions. At the end of this paper, the problem of iterative roots for two well-known planar mappings, that is, Hénon mappings and coupled logistic mappings, are also discussed.
The Healing through Arts (HeARTS) program for children bereaved by cancer: Pilot study findings from Singapore
Authors: Ong Saryna , Loh Travis , Wong Phyllis , Teo Irene
Published: April 2023

Objectives

The article aims to investigate the feasibility, acceptability, and initial efficacy of a short-term 3-day art therapy group for children who have experienced parental death to cancer.

Methods

The study utilized a pretest–posttest design and included children (n = 20) aged 7–12 years. The feasibility of the intervention was measured by recruitment ability, study compliance, and intervention adherence, while acceptability was assessed using a child-reported satisfaction survey. Efficacy was examined using the child-reported Pediatric Quality of Life Inventory (PedsQL), while the emotional, social, and behavioral functioning of children was measured using the parent-reported Strengths and Difficulties Questionnaire. Paired sample t-tests were used for analyses.

Results

The intervention was found to be feasible (80% recruitment rate and 100% session adherence). Acceptability was high, and all participants were satisfied and found the intervention to be helpful. While results did not reach statistical significance, improvements in psychosocial and physical quality of life were reported by all the children post-intervention and at the 3-month follow-up. Parent-reported a decrease in behavioral difficulties scores and an increase in prosocial behavior scores at post-intervention and at the 3-month follow-up.

Significance of results

The 3-day art therapy group intervention was shown to be feasible to conduct and acceptable to the recipients. The intervention shows promise in improving post-death adjustment and quality of life outcomes of children bereaved by parental death due to cancer that were maintained after 3 months. The use of art therapy groups to ameliorate difficulties associated with parental loss and to assist children in coping day-to-day difficulties should be further investigated.
Vanguards of the counter-revolution: the far–right and the French Army’s guerre révolutionnaire doctrine
Authors: Cooney Cian
Published: April 2023

Guerre révolutionnaire doctrine was conceived of as a riposte to the new form of warfare which the French Army encountered and fell victim to in Indochina. Taking inspiration from both the Indochina experience and communist writers, the doctrine inevitably advocated and replicated totalitarian tactics and methods. One of its major tenets was the intrusion of the army into the realm of politics, an incursion which resulted in huge turmoil. Previous studies have centred on a discussion of the doctrine itself, with limited consideration of its impact within political circles. The current article seeks to address this gap in the literature with an exploration of far-right ideological precepts present in guerre révolutionnaire doctrine and to explain why this doctrine struck a chord with l’extrême-droite in France. Given the extent of far-right political action during the Algerian War in defence of l’Algérie française, an examination of this connection is of significant interest.
Social distinctions of directors and firm performance
Authors: Ramachandra Suresh , Rahman Asheq
Published: April 2023

Purpose

This paper aims to examine the effects of the social distinction of company directors on firm performance.

Design/methodology/approach

The social distinction of company directors adds to the firm’s reputation, allowing the firm to access resources and privileges. The indicators of social distinction this study uses are the prenominal titles of directors in Malaysian companies. As Malaysian companies are known to have directors with political connections and the prenominal titles can be intertwined with these connections, to ascertain the effects of social distinction on firm performance, this study examines whether social distinctions proxy and complement political connections in improving firm performance. This study uses Tobin’s Q (TQ) for longer-term performance and gross sales for current-year performance.

Findings

This study finds evidence to suggest that the impact of higher-order titles on Tobin’s Q and sales is greater in politically unconnected firms than in connected firms. This study also finds evidence to suggest that higher-order titles amplify the effect on Tobin’s Q in politically connected firms, whereas lower-order titles amplify sales, both moderated by firm-age. The findings shed light on the mediating variables that contribute to the above, and are robust for alternative performance measures, and account for endogeneity concerns.

Research limitations/implications

The results are generalisable only to countries where social distinctions are of significance.

Practical implications

Future research on political connections should consider social connections that affect firms. Also, such research should prompt the awarders of titles to prohibit the use of titles for pecuniary motives to minimise market imperfections.

Originality/value

Adding to the prior literature on the characteristics of directors and firm performance, this study shows that the social distinctions of directors do matter.
The drivers and barriers of telecommuting: The case of Lebanon during COVID‐19
Authors: Ismail Hussein , Blaique Lama , Syagha Ola
Published: April 2023

This study aims to investigate the barriers and drivers relating to telecommuting as a mode of work in the wake of the coronavirus pandemic. Using a qualitative research design, data from 30 interviews conducted with employees from different departments and specialties in Lebanon were analysed. The results reveal three main themes, namely, technological context, organisational context and national context in relation to the experiences of workers telecommuting during the pandemic. There are limited studies that examine telecommuting in the Middle East region in general and in Lebanon in particular. The study highlights the benefits of telecommuting and offers several organisational and contextual implications that would enhance the adoption of telecommuting in the Middle East region.
Exaptation of Inactivated Host Enzymes for Structural Roles in Orthopoxviruses and Novel Folds of Virus Proteins Revealed by Protein Structure Modeling
Authors: Mutz Pascal , Resch Wolfgang , Faure Guilhem , Senkevich Tatiana G. , Koonin Eugene V. , Moss Bernard
Published: April 2023

Protein structures are more strongly conserved in evolution than are amino acid sequences. Comparative structural analysis is particularly important for inferring the origins of viral proteins that typically evolve at high rates.
Data from Deep Transcriptome Profiling of Multiple Myeloma Using Quantitative Phenotypes
Authors: Griffin Rosalie , Hanson Heidi A. , Avery Brian J. , Madsen Michael J. , Sborov Douglas W. , Camp Nicola J.
Published: April 2023

AbstractBackground:
Transcriptome studies are gaining momentum in genomic epidemiology, and the need to incorporate these data in multivariable models alongside other risk factors brings demands for new approaches.
Methods:
Here we describe SPECTRA, an approach to derive quantitative variables that capture the intrinsic variation in gene expression of a tissue type. We applied the SPECTRA approach to bulk RNA sequencing from malignant cells (CD138+) in patients from the Multiple Myeloma Research Foundation CoMMpass study.
Results:
A set of 39 spectra variables were derived to represent multiple myeloma cells. We used these variables in predictive modeling to determine spectra-based risk scores for overall survival, progression-free survival, and time to treatment failure. Risk scores added predictive value beyond known clinical and expression risk factors and replicated in an external dataset. Spectrum variable S5, a significant predictor for all three outcomes, showed pre-ranked gene set enrichment for the unfolded protein response, a mechanism targeted by proteasome inhibitors which are a common first line agent in multiple myeloma treatment. We further used the 39 spectra variables in descriptive modeling, with significant associations found with tumor cytogenetics, race, gender, and age at diagnosis; factors known to influence multiple myeloma incidence or progression.
Conclusions:
Quantitative variables from the SPECTRA approach can predict clinical outcomes in multiple myeloma and provide a new avenue for insight into tumor differences by demographic groups.
Impact:
The SPECTRA approach provides a set of quantitative phenotypes that deeply profile a tissue and allows for more comprehensive modeling of gene expression with other risk factors.
Supplementary Figure 3 from Sangivamycin-like Molecule 6 Exhibits Potent Anti-Multiple Myeloma Activity through Inhibition of Cyclin-Dependent Kinase-9
Authors: Dolloff Nathan G. , Allen Joshua E. , Dicker David T. , Aqui Nicole , Vogl Dan , Malysz Jozef , Talamo Giampaolo , El-Deiry Wafik S.
Published: April 2023

PDF file, 90K, GSK-3β and CDK1 inhibitors fail to reduce MM cell viability.
Supplementary Figure 2 from Sangivamycin-like Molecule 6 Exhibits Potent Anti-Multiple Myeloma Activity through Inhibition of Cyclin-Dependent Kinase-9
Authors: Dolloff Nathan G. , Allen Joshua E. , Dicker David T. , Aqui Nicole , Vogl Dan , Malysz Jozef , Talamo Giampaolo , El-Deiry Wafik S.
Published: April 2023

PDF file, 106K, SLM6 toxicity studies in C57BL/6 immunocompetent mice.
Supplementary Figure 4 from Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells
Authors: Ewton Daina Z. , Hu Jing , Vilenchik Maria , Deng Xiaobing , Luk Kin-chun , Polonskaia Ann , Hoffman Ann F. , Zipf Karen , Boylan John F. , Friedman Eileen A.
Published: April 2023

PDF file - 286K
Supplementary Figure 1 from Sangivamycin-like Molecule 6 Exhibits Potent Anti-Multiple Myeloma Activity through Inhibition of Cyclin-Dependent Kinase-9
Authors: Dolloff Nathan G. , Allen Joshua E. , Dicker David T. , Aqui Nicole , Vogl Dan , Malysz Jozef , Talamo Giampaolo , El-Deiry Wafik S.
Published: April 2023

PDF file, 121K, Screening for cytotoxicity of SLM3 in cancer cell lines derived from multiple tumor types.
Supplementary Figure 3 from Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells
Authors: Ewton Daina Z. , Hu Jing , Vilenchik Maria , Deng Xiaobing , Luk Kin-chun , Polonskaia Ann , Hoffman Ann F. , Zipf Karen , Boylan John F. , Friedman Eileen A.
Published: April 2023

PDF file - 488K
supplementary Figure Legends 1-2 from Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment
Authors: Stokes Jayme B. , Adair Sara J. , Slack-Davis Jill K. , Walters Dustin M. , Tilghman Robert W. , Hershey E. Dan , Lowrey Bryce , Thomas Keena S. , Bouton Amy H. , Hwang Rosa F. , Stelow Edward B. , Parsons J. Thomas , Bauer Todd W.
Published: April 2023

PDF file - 72K
Supplementary Figure 2 from Inhibition of Focal Adhesion Kinase by PF-562,271 Inhibits the Growth and Metastasis of Pancreatic Cancer Concomitant with Altering the Tumor Microenvironment
Authors: Stokes Jayme B. , Adair Sara J. , Slack-Davis Jill K. , Walters Dustin M. , Tilghman Robert W. , Hershey E. Dan , Lowrey Bryce , Thomas Keena S. , Bouton Amy H. , Hwang Rosa F. , Stelow Edward B. , Parsons J. Thomas , Bauer Todd W.
Published: April 2023

PDF file - 85K
Supplementary Material and Methods, Figure Legends and Tables 1-2 from Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
Authors: Liu Li , Shi Hong , Liu Yuan , Anderson Amber , Peterson John , Greger James , Martin Anne-Marie , Gilmer Tona M.
Published: April 2023

Supplementary Material and Methods, Figure Legends and Tables 1-2 from Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
Supplementary Figure 3 from Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
Authors: Liu Li , Shi Hong , Liu Yuan , Anderson Amber , Peterson John , Greger James , Martin Anne-Marie , Gilmer Tona M.
Published: April 2023

Supplementary Figure 3 from Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
Supplementary Figure Legends 1-4 from Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase
Authors: Chen Chun-Te , Yamaguchi Hirohito , Lee Hong-Jen , Du Yi , Lee Heng-Huan , Xia Weiya , Yu Wen-Hsuan , Hsu Jennifer L. , Yen Chia-Jui , Sun Hui-Lung , Wang Yan , Yeh Edward T.H. , Hortobagyi Gabriel N. , Hung Mien-Chie
Published: April 2023

Supplementary Figure Legends 1-4 from Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase
Supplementary Figure 2 from Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
Authors: Liu Li , Shi Hong , Liu Yuan , Anderson Amber , Peterson John , Greger James , Martin Anne-Marie , Gilmer Tona M.
Published: April 2023

Supplementary Figure 2 from Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
Supplementary Table 8 from Development of Gene Expression–Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors
Authors: Moreaux Jérôme , Rème Thierry , Leonard Wim , Veyrune Jean-Luc , Requirand Guilhem , Goldschmidt Hartmut , Hose Dirk , Klein Bernard
Published: April 2023

PDF file - 48K, Genes underexpressed in decitabine treated HMCLs in the studies conducted by Heller G et al. and the current study.
Supplementary Table 7 from Development of Gene Expression–Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors
Authors: Moreaux Jérôme , Rème Thierry , Leonard Wim , Veyrune Jean-Luc , Requirand Guilhem , Goldschmidt Hartmut , Hose Dirk , Klein Bernard
Published: April 2023

PDF file - 48K, Genes overexpressed in decitabine treated HMCLs in the studies conducted by Heller G et al. and the current study.
Supplementary Figures 1-4 from B7-H3 Silencing Increases Paclitaxel Sensitivity by Abrogating Jak2/Stat3 Phosphorylation
Authors: Liu Hao , Tekle Christina , Chen Yih-Wen , Kristian Alexandr , Zhao Yuhua , Zhou Ming , Liu Zixing , Ding Yan , Wang Bin , Mælandsmo Gunhild Mari , Nesland Jahn Marthin , Fodstad Oystein , Tan Ming
Published: April 2023

Supplementary Figures 1-4 from B7-H3 Silencing Increases Paclitaxel Sensitivity by Abrogating Jak2/Stat3 Phosphorylation
Supplementary Figure Legends 1-4 from B7-H3 Silencing Increases Paclitaxel Sensitivity by Abrogating Jak2/Stat3 Phosphorylation
Authors: Liu Hao , Tekle Christina , Chen Yih-Wen , Kristian Alexandr , Zhao Yuhua , Zhou Ming , Liu Zixing , Ding Yan , Wang Bin , Mælandsmo Gunhild Mari , Nesland Jahn Marthin , Fodstad Oystein , Tan Ming
Published: April 2023

Supplementary Figure Legends 1-4 from B7-H3 Silencing Increases Paclitaxel Sensitivity by Abrogating Jak2/Stat3 Phosphorylation
Supplementary Table 5 from Development of Gene Expression–Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors
Authors: Moreaux Jérôme , Rème Thierry , Leonard Wim , Veyrune Jean-Luc , Requirand Guilhem , Goldschmidt Hartmut , Hose Dirk , Klein Bernard
Published: April 2023

PDF file - 43K, Prognostic value of decitabine deregulated genes in primary MMC of newly-diagnosed patients.
Supplementary Figure Legend from 3,5-Bis(2,4-Difluorobenzylidene)-4-piperidone, a Novel Compound That Affects Pancreatic Cancer Growth and Angiogenesis
Authors: Subramaniam Dharmalingam , Nicholes Nathan D. , Dhar Animesh , Umar Shahid , Awasthi Vibhudutta , Welch Danny R. , Jensen Roy A. , Anant Shrikant
Published: April 2023

PDF file - 68K
Supplementary Table 2 from Development of Gene Expression–Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors
Authors: Moreaux Jérôme , Rème Thierry , Leonard Wim , Veyrune Jean-Luc , Requirand Guilhem , Goldschmidt Hartmut , Hose Dirk , Klein Bernard
Published: April 2023

PDF file - 43K, Cell viability of HMCLs treated with either 0.5 μM decitabine for 7 days. Date are the mean percentages � SD of viable cells evaluated by trypan blue exclusion (3 experiments).
Supplementary Figure 1 from 3,5-Bis(2,4-Difluorobenzylidene)-4-piperidone, a Novel Compound That Affects Pancreatic Cancer Growth and Angiogenesis
Authors: Subramaniam Dharmalingam , Nicholes Nathan D. , Dhar Animesh , Umar Shahid , Awasthi Vibhudutta , Welch Danny R. , Jensen Roy A. , Anant Shrikant
Published: April 2023

PDF file - 159K
Supplementary Table 1 from Development of Gene Expression–Based Score to Predict Sensitivity of Multiple Myeloma Cells to DNA Methylation Inhibitors
Authors: Moreaux Jérôme , Rème Thierry , Leonard Wim , Veyrune Jean-Luc , Requirand Guilhem , Goldschmidt Hartmut , Hose Dirk , Klein Bernard
Published: April 2023

PDF file - 61K, Clinical patient data for age, serum-β2-microglobulin, and plasma cell infiltration in the Heidelberg/Montpellier-group (HM) and the Arkansas cohort. Median value and range are given. NA, not available. ISS, International Staging System.
Supplementary Table 2 from PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity
Authors: Yuan Jing , Mehta Pramod P. , Yin Min-Jean , Sun Shaoxian , Zou Aihua , Chen Jeffrey , Rafidi Kristina , Feng Zheng , Nickel Jeffrey , Engebretsen Jon , Hallin Jill , Blasina Alessandra , Zhang Eric , Nguyen Leslie , Sun Minghao , Vogt Peter K. , McHarg Aileen , Cheng Hengmiao , Christensen James G. , Kan Julie L.C. , Bagrodia Shubha
Published: April 2023

PDF file - 73K
Supplementary Figure Legends 1-2 from PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity
Authors: Yuan Jing , Mehta Pramod P. , Yin Min-Jean , Sun Shaoxian , Zou Aihua , Chen Jeffrey , Rafidi Kristina , Feng Zheng , Nickel Jeffrey , Engebretsen Jon , Hallin Jill , Blasina Alessandra , Zhang Eric , Nguyen Leslie , Sun Minghao , Vogt Peter K. , McHarg Aileen , Cheng Hengmiao , Christensen James G. , Kan Julie L.C. , Bagrodia Shubha
Published: April 2023

PDF file - 51K
Supplementary Figure 1 from hTERT Promotes Imatinib Resistance in Chronic Myeloid Leukemia Cells: Therapeutic Implications
Authors: Deville Laure , Hillion Josette , Pendino Frédéric , Samy Mona , Nguyen Eric , Ségal-Bendirdjian Evelyne
Published: April 2023

Supplementary Figure 1 from hTERT Promotes Imatinib Resistance in Chronic Myeloid Leukemia Cells: Therapeutic Implications
Supplementary Figure 1 from PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity
Authors: Yuan Jing , Mehta Pramod P. , Yin Min-Jean , Sun Shaoxian , Zou Aihua , Chen Jeffrey , Rafidi Kristina , Feng Zheng , Nickel Jeffrey , Engebretsen Jon , Hallin Jill , Blasina Alessandra , Zhang Eric , Nguyen Leslie , Sun Minghao , Vogt Peter K. , McHarg Aileen , Cheng Hengmiao , Christensen James G. , Kan Julie L.C. , Bagrodia Shubha
Published: April 2023

PDF file - 278K
Supplementary Tables 1 - 3, Figure 1 from Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth
Authors: Yakes F. Michael , Chen Jason , Tan Jenny , Yamaguchi Kyoko , Shi Yongchang , Yu Peiwen , Qian Fawn , Chu Felix , Bentzien Frauke , Cancilla Belinda , Orf Jessica , You Andrew , Laird A. Douglas , Engst Stefan , Lee Lillian , Lesch Justin , Chou Yu-Chien , Joly Alison H.
Published: April 2023

PDF file - 104KB
Supplementary Figures 1-8 from A Human Model of Epithelial to Mesenchymal Transition to Monitor Drug Efficacy in Hepatocellular Carcinoma Progression
Authors: van Zijl Franziska , Mall Sabine , Machat Georg , Pirker Christine , Zeillinger Robert , Weinhaeusel Andreas , Bilban Martin , Berger Walter , Mikulits Wolfgang
Published: April 2023

Supplementary Figures 1-8 from A Human Model of Epithelial to Mesenchymal Transition to Monitor Drug Efficacy in Hepatocellular Carcinoma Progression
Supplementary Methods from An Antibody Fusion Protein for Cancer Immunotherapy Mimicking IL-15 trans-Presentation at the Tumor Site
Authors: Kermer Vanessa , Baum Volker , Hornig Nora , Kontermann Roland E. , Müller Dafne
Published: April 2023

PDF file, 64KB, supplemental data, S1, Cloning, expression and purification of the recombinant fusion proteins.
Supplementary Figure Legends 1-8 from A Human Model of Epithelial to Mesenchymal Transition to Monitor Drug Efficacy in Hepatocellular Carcinoma Progression
Authors: van Zijl Franziska , Mall Sabine , Machat Georg , Pirker Christine , Zeillinger Robert , Weinhaeusel Andreas , Bilban Martin , Berger Walter , Mikulits Wolfgang
Published: April 2023

Supplementary Figure Legends 1-8 from A Human Model of Epithelial to Mesenchymal Transition to Monitor Drug Efficacy in Hepatocellular Carcinoma Progression
Supplementary Material and Methods from Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-Deficient Astrocytes
Authors: Banerjee Sutapa , Gianino Scott M. , Gao Feng , Christians Uwe , Gutmann David H.
Published: April 2023

Supplementary Material and Methods from Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-Deficient Astrocytes
Supplementary Figure Legends from Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-Deficient Astrocytes
Authors: Banerjee Sutapa , Gianino Scott M. , Gao Feng , Christians Uwe , Gutmann David H.
Published: April 2023

Supplementary Figure Legends from Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-Deficient Astrocytes
Supplementary Figure 6 from Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-Deficient Astrocytes
Authors: Banerjee Sutapa , Gianino Scott M. , Gao Feng , Christians Uwe , Gutmann David H.
Published: April 2023

Supplementary Figure 6 from Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-Deficient Astrocytes
Supplementary Materials, Tables 1-2, Figure 1 from Targeted Nanogels: A Versatile Platform for Drug Delivery to Tumors
Authors: Murphy Eric A. , Majeti Bharat K. , Mukthavaram Rajesh , Acevedo Lisette M. , Barnes Leo A. , Cheresh David A.
Published: April 2023

Supplementary Materials, Tables 1-2, Figure 1 from Targeted Nanogels: A Versatile Platform for Drug Delivery to Tumors
Supplementary Figure Legends from FcRL5 as a Target of Antibody–Drug Conjugates for the Treatment of Multiple Myeloma
Authors: Elkins Kristi , Zheng Bing , Go MaryAnn , Slaga Dionysos , Du Changchun , Scales Suzie J. , Yu Shang-Fan , McBride Jacqueline , de Tute Ruth , Rawstron Andy , Jack Andrew S. , Ebens Allen , Polson Andrew G.
Published: April 2023

PDF file - 25KB
Supplementary Figure 1 from Combining PARP-1 Inhibition and Radiation in Ewing Sarcoma Results in Lethal DNA Damage
Authors: Lee Hae-June , Yoon Changhwan , Schmidt Benjamin , Park Do Joong , Zhang Alexia Y. , Erkizan Hayriye V. , Toretsky Jeffrey A. , Kirsch David G. , Yoon Sam S.
Published: April 2023

PDF - 32KB, Chemical structure of olaparib
Supplementary Figure Legend from ErbB3 Inhibitory Surrobodies Inhibit Tumor Cell Proliferation In Vitro and In Vivo
Authors: Foreman Pamela K. , Gore Medini , Kobel Philip A. , Xu Li , Yee Helena , Hannum Charles , Ho Hoangdung , Wang Sandra M. , Tran Hieu V. , Horowitz Michael , Horowitz Lawrence , Bhatt Ramesh R.
Published: April 2023

PDF file, 7KB.
Supplementary Figure 5 from ErbB3 Inhibitory Surrobodies Inhibit Tumor Cell Proliferation In Vitro and In Vivo
Authors: Foreman Pamela K. , Gore Medini , Kobel Philip A. , Xu Li , Yee Helena , Hannum Charles , Ho Hoangdung , Wang Sandra M. , Tran Hieu V. , Horowitz Michael , Horowitz Lawrence , Bhatt Ramesh R.
Published: April 2023

PDF file, 39KB, Surrobody Treatment Reduces Cell Surface ErbB3.
Supplementary Figure 4 from ErbB3 Inhibitory Surrobodies Inhibit Tumor Cell Proliferation In Vitro and In Vivo
Authors: Foreman Pamela K. , Gore Medini , Kobel Philip A. , Xu Li , Yee Helena , Hannum Charles , Ho Hoangdung , Wang Sandra M. , Tran Hieu V. , Horowitz Michael , Horowitz Lawrence , Bhatt Ramesh R.
Published: April 2023

PDF file, 41KB, Activities of Surrobodies Combined with Cetuximab.
Supplementary Figure 3 from ErbB3 Inhibitory Surrobodies Inhibit Tumor Cell Proliferation In Vitro and In Vivo
Authors: Foreman Pamela K. , Gore Medini , Kobel Philip A. , Xu Li , Yee Helena , Hannum Charles , Ho Hoangdung , Wang Sandra M. , Tran Hieu V. , Horowitz Michael , Horowitz Lawrence , Bhatt Ramesh R.
Published: April 2023

PDF file, 53KB, Activity of SL-176 Combined with Trastuzumab.
Supplementary Figure 2 from Smoking Induces Epithelial-to-Mesenchymal Transition in Non–Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-Cadherin
Authors: Nagathihalli Nagaraj S. , Massion Pierre P. , Gonzalez Adriana L. , Lu Pengcheng , Datta Pran K.
Published: April 2023

PDF file, 132K, CSC induces EMT.
Supplementary Figure 2 from ErbB3 Inhibitory Surrobodies Inhibit Tumor Cell Proliferation In Vitro and In Vivo
Authors: Foreman Pamela K. , Gore Medini , Kobel Philip A. , Xu Li , Yee Helena , Hannum Charles , Ho Hoangdung , Wang Sandra M. , Tran Hieu V. , Horowitz Michael , Horowitz Lawrence , Bhatt Ramesh R.
Published: April 2023

PDF file, 85KB, Specificity of Surrobody Binding.
Supplementary Methods and Figure Legends from The Tyrosine Kinase Inhibitor E-3810 Combined with Paclitaxel Inhibits the Growth of Advanced-Stage Triple-Negative Breast Cancer Xenografts
Authors: Bello Ezia , Taraboletti Giulia , Colella Gennaro , Zucchetti Massimo , Forestieri Daniele , Licandro Simonetta A. , Berndt Alexander , Richter Petra , D'Incalci Maurizio , Cavalletti Ennio , Giavazzi Raffaella , Camboni Gabriella , Damia Giovanna
Published: April 2023

PDF file - 101KB
Supplementary Tables 1 - 3, Figure Legend from Targeting the Inhibitor of Apoptosis Proteins as a Novel Therapeutic Strategy in Medulloblastoma
Authors: Keating Joanna , Tsoli Maria , Hallahan Andrew R. , Ingram Wendy J. , Haber Michelle , Ziegler David S.
Published: April 2023

PDF file - 47K, Supplementary Table 1 The combinatorial index of medulloblastoma cell lines treated with a combination of 1uM LBW-242 and 2 Gy (Daoy, D283) or 4Gy (UW228) irradiation in a colony formation assay. A CI of < 1 denotes a synergistic interaction, a CI of 1 +/-0.2 denotes an additive interaction, and a CI of > 1 indicates an antagonistic interaction. Supplementary Table 2: Clinical characteristics of patients from which short term primary tumor cultures were derived.Supplementary Table 3: The ID50 of medulloblastoma cell lines and primary cultures treated with LBW-242 and Cisplatin, calculated from synergy assay curves using interpolated x values (Graph Pad Prism 5). (IA = Inactive as single agent; N/A = not applicable.)
Supplementary Figure 4 from The Tyrosine Kinase Inhibitor E-3810 Combined with Paclitaxel Inhibits the Growth of Advanced-Stage Triple-Negative Breast Cancer Xenografts
Authors: Bello Ezia , Taraboletti Giulia , Colella Gennaro , Zucchetti Massimo , Forestieri Daniele , Licandro Simonetta A. , Berndt Alexander , Richter Petra , D'Incalci Maurizio , Cavalletti Ennio , Giavazzi Raffaella , Camboni Gabriella , Damia Giovanna
Published: April 2023

PDF file - 63KB, Circulating factors in plasma of mice bearing MDA-MB-231 tumors untreated or treated with E-3810 (E), brivanib (B), sunitinib (S), paclitaxel (PTX) and their combinations as described in Material amd Methods.
Supplementary Figure 1 from The Tyrosine Kinase Inhibitor E-3810 Combined with Paclitaxel Inhibits the Growth of Advanced-Stage Triple-Negative Breast Cancer Xenografts
Authors: Bello Ezia , Taraboletti Giulia , Colella Gennaro , Zucchetti Massimo , Forestieri Daniele , Licandro Simonetta A. , Berndt Alexander , Richter Petra , D'Incalci Maurizio , Cavalletti Ennio , Giavazzi Raffaella , Camboni Gabriella , Damia Giovanna
Published: April 2023

PDF file - 51KB, Body weights of MDA-MB-231 bearing mice treated with E-3810, 5FU, DDP and their combinations.
Supplementary Figure Legends 1-13 from Sorafenib Sensitizes (−)-Gossypol-Induced Growth Suppression in Androgen-Independent Prostate Cancer Cells via Mcl-1 Inhibition and Bak Activation
Authors: Lian Jiqin , Ni Zhenhong , Dai Xufang , Su Chang , Smith Amber Rae , Xu Liang , He Fengtian
Published: April 2023

PDF file - 135K
Supplementary Figure Legends from Targeting Plasminogen Activator Inhibitor-1 Inhibits Angiogenesis and Tumor Growth in a Human Cancer Xenograft Model
Authors: Gomes-Giacoia Evan , Miyake Makito , Goodison Steve , Rosser Charles J.
Published: April 2023

PDF - 101KB, Legends for supplementary figures 1-5.
Supplementary Figure 14 from Sorafenib Sensitizes (−)-Gossypol-Induced Growth Suppression in Androgen-Independent Prostate Cancer Cells via Mcl-1 Inhibition and Bak Activation
Authors: Lian Jiqin , Ni Zhenhong , Dai Xufang , Su Chang , Smith Amber Rae , Xu Liang , He Fengtian
Published: April 2023

PDF file - 225K
Supplementary Figure Legend from Treatment with Gefitinib or Lapatinib Induces Drug Resistance through Downregulation of Topoisomerase IIα Expression
Authors: Bhosle Jaishree , Kiakos Konstantinos , Porter Andrew C.G. , Wu Jenny , Makris Andreas , Hartley John A , Hochhauser Daniel
Published: April 2023

PDF file - 60K
Supplementary Figure 2 from Treatment with Gefitinib or Lapatinib Induces Drug Resistance through Downregulation of Topoisomerase IIα Expression
Authors: Bhosle Jaishree , Kiakos Konstantinos , Porter Andrew C.G. , Wu Jenny , Makris Andreas , Hartley John A , Hochhauser Daniel
Published: April 2023

PDF file - 49K, Cell cycle analysis following gefitinib and lapatinib.
Supplementary Figure 2 from Targeting Plasminogen Activator Inhibitor-1 Inhibits Angiogenesis and Tumor Growth in a Human Cancer Xenograft Model
Authors: Gomes-Giacoia Evan , Miyake Makito , Goodison Steve , Rosser Charles J.
Published: April 2023

PDF - 1338KB, A, About 103 urothelial cells (T24-PAI-1KD-19, T24-PAI-1KD-22, UM-UC-14-PAI-1KD-4, UM-UC-14-PAI-1KD-17) were seeded in 6 well plates and incubated for 14 days. After 14 days, colonies were fixed with 6.0% glutaraldehyde, stained with 0.5% crystal violet and counted under light microscopy. Data were represented as mean + SD of three independent replicates. B, About 2 x 103 urothelial cells (T24-PAI-1KD-19, T24-PAI-1KD-22, UM-UC-14-PAI-1KD-4, UM-UC-14-PAI-1KD-17) were mixed in agar solution and fresh complete media and seeded in 96 well plates. Cells were incubated for 6-8 days. Colony formation was quantified using the fluorescent cell stain CyQuant GR Dye (Cell Biolabs Inc., San Diego, CA) in the FLUOstar Optima Reader. Data were represented as mean + SD of three independent replicates. All experiments were repeated at least three times. Targeting PAI-1 was noted to retard colony formation. *, p < 0.05.
Supplementary Figure 1 from Targeting Plasminogen Activator Inhibitor-1 Inhibits Angiogenesis and Tumor Growth in a Human Cancer Xenograft Model
Authors: Gomes-Giacoia Evan , Miyake Makito , Goodison Steve , Rosser Charles J.
Published: April 2023

PDF - 1449KB, PAI-1 expression in T24-PAI-1KD-19, T24-PAI-1KD-22, UM-UC-14-PAI-1KD-4, UM-UC-14-PAI-1KD-17, HeLa-PAI-1OE-12 and HeLa-PAI-1OE-18 clones was confirmed by immunoblotting (A), quantitative PCR (B), and secreted protein by ELISA (C) and compared to control. D, Protein lysates from T24, UM-UC-14, UROtsa and HeLa cells treated with or without tiplaxtinin (0-50 microM) and from the above clones were electrophoresed on 10% SDS-polyacrylamide gels containing plasminogen and uPA under non-reducing conditions followed by staining with Coomassie blue. PAI-1 activity was indicated as lytic zones of plasmin generation. Specifically in our in vitro zymogen activity assay, we confirmed in a dose dependent manner that tiplaxtinin stimulates the conversion of zymogen to mature enzyme (plasmin) resulting in an increase in enzymatic activity. Similar, clones in which PAI-1 was silence noted conversion of zymogen to mature enzyme resulting in an increase in enzymatic activity. *, p < 0.05.
Supplementary Table 6 from Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion
Authors: Saintigny Pierre , Peng Shaohua , Zhang Li , Sen Banibrata , Wistuba Ignacio I. , Lippman Scott M. , Girard Luc , Minna John D. , Heymach John V. , Johnson Faye M.
Published: April 2023

PDF file, 99K, Detailed mutations identified in the Eph receptors family in NSCLC.
Supplementary Table 9 from Genome and Transcriptome Sequencing in Prospective Metastatic Triple-Negative Breast Cancer Uncovers Therapeutic Vulnerabilities
Authors: Craig David W. , O'Shaughnessy Joyce A. , Kiefer Jeffrey A. , Aldrich Jessica , Sinari Shripad , Moses Tracy M. , Wong Shukmei , Dinh Jennifer , Christoforides Alexis , Blum Joanne L. , Aitelli Cristi L. , Osborne Cynthia R. , Izatt Tyler , Kurdoglu Ahmet , Baker Angela , Koeman Julie , Barbacioru Catalin , Sakarya Onur , De La Vega Francisco M. , Siddiqui Asim , Hoang Linh , Billings Paul R. , Salhia Bodour , Tolcher Anthony W. , Trent Jeffrey M. , Mousses Spyro , Von Hoff Daniel , Carpten John D.
Published: April 2023

XLSX file - 45K, Genes containing breakpoint from translocation in mTNBC
Supplementary Table 3 from Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion
Authors: Saintigny Pierre , Peng Shaohua , Zhang Li , Sen Banibrata , Wistuba Ignacio I. , Lippman Scott M. , Girard Luc , Minna John D. , Heymach John V. , Johnson Faye M.
Published: April 2023

PDF file, 87K, Multicovariate analysis showing the association between EphA4 gene expression and overall survival in an independent cohort of patients resected for a lung adenocarcinoma.