bluuebunny/crossref_metadata_2025 huggingface dataset:
The value of L3 skeletal muscle index in evaluating preoperative nutritional risk and long-term prognosis in colorectal cancer patients
Authors: Wang Shengqiang , Xie Hailun , Gong Yizhen , Kuang Jiaan , Yan Ling , Ruan Guotian , Gao Feng , Gan Jialiang
Published: May 2020

L3 skeletal muscle index (L3SMI) was reportedly related to postoperative outcomes. We aimed to investigate the value of L3SMI in evaluating preoperative nutritional risk and long-term prognosis in colorectal cancer (CRC) patients. We retrospectively enrolled 400 CRC patients who underwent surgery from January 2012 to December 2014. The L3SMI was calculated by preoperative computed tomography (CT) and classified into two groups by gender quartile method. We found that the CT diagnostic criteria of sarcopenia in South China population was: male ≤38.89cm2/m2, female ≤33.28cm2/m2. Multivariate logistic regression analysis showed that low L3SMI was an independent risk factor for preoperative nutritional risk (p < 0.001). Kaplan-Meier survival curves showed that low status group had significantly lower disease-free survival (p = 0.004) and overall survival (p = 0.001), especially in TNM II stage. Multivariate Cox regression analysis revealed preoperative low L3SMI adversely affected disease-free survival (p < 0.001, HR 1.894 (95% CI: 1.330–2.698)), and overall survival (p < 0.001, HR 2.030 (95% CI: 1.420–2.902)). In conclusion, L3SMI is a useful supplement for screening preoperative nutritional risk and diagnosing sarcopenia, and a potential clinical indicator that can be used to predict the prognosis of CRC patients, especially TNM stage II patients.
Increasing carbohydrate oxidation improves contractile reserves and prevents hypertrophy in porcine right heart failure
Authors: Bøgh Nikolaj , Hansen Esben S. S. , Omann Camilla , Lindhardt Jakob , Nielsen Per M. , Stephenson Robert S. , Laustsen Christoffer , Hjortdal Vibeke E. , Agger Peter
Published: May 2020

In heart failure, myocardial overload causes vast metabolic changes that impair cardiac energy production and contribute to deterioration of contractile function. However, metabolic therapy is not used in heart failure care. We aimed to investigate the interplay between cardiac function and myocardial carbohydrate metabolism in a large animal heart failure model. Using magnetic resonance spectroscopy with hyperpolarized pyruvate and magnetic resonance imaging at rest and during pharmacological stress, we investigated the in-vivo cardiac pyruvate metabolism and contractility in a porcine model of chronic pulmonary insufficiency causing right ventricular volume overload. To assess if increasing the carbohydrate metabolic reserve improves the contractile reserve, a group of animals were fed dichloroacetate, an activator of pyruvate oxidation. Volume overload caused heart failure with decreased pyruvate dehydrogenase flux and poor ejection fraction reserve. The animals treated with dichloroacetate had a larger contractile response to dobutamine stress than non-treated animals. Further, dichloroacetate prevented myocardial hypertrophy. The in-vivo metabolic data were validated by mitochondrial respirometry, enzyme activity assays and gene expression analyses. Our results show that pyruvate dehydrogenase kinase inhibition improves the contractile reserve and decreases hypertrophy by augmenting carbohydrate metabolism in porcine heart failure. The approach is promising for metabolic heart failure therapy.
Bragg-Berry flat reflectors for transparent computer-generated holograms and waveguide holography with visible color playback capability
Authors: Cho Seong Yong , Ono Masaru , Yoshida Hiroyuki , Ozaki Masanori
Published: May 2020

Various approaches are being pursued to realize compact optical elements with the ability to manipulate light, but it is difficult to simultaneously achieve high reflectivity and the ability to see through the element. Here, we present a reflective computer-generated hologram that is completely transparent in the visible, based on the Berry (geometric) phase in a self-organizing Bragg reflector. The Bragg reflector has a helical dielectric tensor distribution with the phase information imprinted in the distribution of the optic axis on the substrate. The structure possesses only a single Fourier component and high-order reflections are suppressed; thus, the device appears completely transparent by setting the main reflection band outside the visible range for all angles of incidence accessible by ambient light. On the other hand, the encoded phase information can be played back using visible light by increasing the accessible incidence angle, which we demonstrate experimentally by (i) attaching a coupling prism, and (ii) integrating the device in a waveguide. Bragg-Berry reflectors thus enable a new route to realize advanced optical elements with no apparent reflection in the visible region.
Management of Atrio-esophageal Fistula Induced by Radiofrequency Catheter Ablation in Atrial Fibrillation Patients: a Case Series
Authors: Kim Yun Gi , Shim Jaemin , Lee Kwang-No , Lim Ju Yong , Chung Jae Ho , Jung Jae Seung , Choi Jong-Il , Lee Sung Ho , Son Ho Sung , Kim Young-Hoon
Published: May 2020

Atrio-esophageal fistula (AEF) is one of the most devastating complication of radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) and surgical repair is strongly recommended. However, optimal surgical approach remains to be elucidated. We retrospectively reviewed AEF cases that occurred after RFCA in a single center and evaluated the clinical results of different surgical approach. Surgical or endoscopic repair was attempted in five AF patients who underwent RFCA. Atrio-esophageal fistula and mediastinal infection was not controlled in the patient who underwent endoscopic repair eventually died. Lethal cerebral air embolism occurred two days after surgery in a patient who underwent esophageal repair only. Primary surgical repair of both the left atrium (LA) and esophagus was performed in the remaining three patients. Among these three patients, two underwent external LA repair and the remaining had internal LA repair via open-heart surgery. External repair of the LA was unsuccessful and one patient dies and another had to undergo second operation with internal repair of the LA. The patient who underwent internal LA repair during the first operation survived without additional surgery. Furthermore, we applied veno-arterial extracorporeal membrane oxygenation (VA-ECMO) with artificial induction of ventricular fibrillation in this patient to prevent air and septic embolism and she had no neurologic sequelae. In summary, surgical correction can be considered preferentially to correct AEF. Open-heart surgical repair of LA from the internal side seems to be an acceptable surgical method. Application of VA-ECMO with artificial induction of ventricular fibrillation might be effective to prevent air and septic embolism.
Seasonal concentration distribution of PM1.0 and PM2.5 and a risk assessment of bound trace metals in Harbin, China: Effect of the species distribution of heavy metals and heat supply
Authors: Wang Kun , Wang Weiye , Li Lili , Li Jianju , Wei Liangliang , Chi Wanqiu , Hong Lijing , Zhao Qingliang , Jiang Junqiu
Published: May 2020

To clarify the potential carcinogenic/noncarcinogenic risk posed by particulate matter (PM) in Harbin, a city in China with the typical heat supply, the concentrations of PM1.0 and PM2.5 were analyzed from Nov. 2014 to Nov. 2015, and the compositions of heavy metals and water-soluble ions (WSIs) were determined. The continuous heat supply from October to April led to serious air pollution in Harbin, thus leading to a significant increase in particle numbers (especially for PM1.0). Specifically, coal combustion under heat supply conditions led to significant emissions of PM1.0 and PM2.5, especially heavy metals and secondary atmospheric pollutants, including SO42−, NO3−, and NH4+. Natural occurrences such as dust storms in April and May, as well as straw combustion in October, also contributed to the increase in WSIs and heavy metals. The exposure risk assessment results demonstrated that Zn was the main contributor to the average daily dose through ingestion and inhalation, ADDIng and ADDinh, respectively, among the 8 heavy metals, accounting for 51.7–52.5% of the ADDIng values and 52.5% of the ADDinh values. The contribution of Zn was followed by those of Pb, Cr, Cu and Mn, while those of Ni, Cd, and Co were quite low (<2.2%).
Impact of implementing a non-restrictive antibiotic stewardship program in an emergency department: a four-year quasi-experimental prospective study
Authors: Savoldi Alessia , Foschi Federico , Kreth Florian , Gladstone Beryl Primrose , Carrara Elena , Eisenbeis Simone , Buhl Michael , Marasca Giuseppe , Bovo Chiara , Malek Nisar Peter , Tacconelli Evelina
Published: May 2020

Antibiotic resistance is increasing worldwide. The implementation of antibiotic stewardship programmes (ASPs) is of utmost importance to optimize antibiotic use in order to prevent resistance development without harming patients. The emergency department (ED), cornerstone between hospital and community, represents a crucial setting for addressing ASP implementation; however, evidence data on ASP in ED are poor. In this study, a 4-year, non-restrictive, multi-faceted ASP was implemented in a general ED with the aim to evaluate its impact on antibiotic use and costs. Secondly, the study focused on assessing the impact on length of hospital stay (LOS), Clostridioides difficile infection (CDI) incidence rate, and mortality in the patients’ group admitted from ED to medical wards. The ASP implementation was associated with a reduction of antibiotic use and costs. A mild but sustained LOS decrease in all medical wards and a significant downward trend of CDI incidence rate were observed, while mortality did not significantly change. In conclusion, the implementation of our ED-based ASP has demonstrated to be feasible and safe and might clinically benefit the hospital admitted patients’ group. Further research is needed to identify the most suitable ASP design for ED and the key outcome measures to reliably assess its effectiveness.
A swift technique to hydrophobize graphene and increase its mechanical stability and charge carrier density
Authors: Madauß Lukas , Pollmann Erik , Foller Tobias , Schumacher Jens , Hagemann Ulrich , Heckhoff Tobias , Herder Matthias , Skopinski Lucia , Breuer Lars , Hierzenberger Anke , Wittmar Alexandra , Lebius Henning , Benyagoub Abdenacer , Ulbricht Mathias , Joshi Rakesh , Schleberger Marika
Published: May 2020

Despite the improvement of the quality of CVD grown single-layer graphene on copper substrates, transferring the two-dimensional layer without introducing any unintentional defects still poses a challenge. While many approaches focus on optimizing the transfer itself or on necessary post-transfer cleaning steps, we have focused on developing a pre-treatment of the monolayer graphene on copper to improve the quality and reproducibility of the transfer process. By pressing an ethylene-vinyl acetate copolymer foil onto the monolayer graphene on copper using a commercially available vacuum bag sealer graphene is stabilized by the attachment of functional carbon groups. As a result, we are able to transfer graphene without the need of any supporting layer in an all-H2O wet-chemical transfer step. Despite the general belief that the crumbling of graphene without a support layer in a H2O environment is caused due to differences in surface energy, we will show that this assumption is false and that this behavior is caused rather by the polar interactions between graphene and water. Suppressing these interactions protects graphene from ripping and results in extremely clean, highly crystalline graphene with a coverage close to 100%.
Macroscale and microcircuit dissociation of focal and generalized human epilepsies
Authors: Weng Yifei , Larivière Sara , Caciagli Lorenzo , Vos de Wael Reinder , Rodríguez-Cruces Raúl , Royer Jessica , Xu Qiang , Bernasconi Neda , Bernasconi Andrea , Thomas Yeo B. T. , Lu Guangming , Zhang Zhiqiang , Bernhardt Boris C.
Published: May 2020

Thalamo-cortical pathology plays key roles in both generalized and focal epilepsies, but there is little work directly comparing these syndromes at the level of whole-brain mechanisms. Using multimodal imaging, connectomics, and computational simulations, we examined thalamo-cortical and cortico-cortical signatures and underlying microcircuits in 96 genetic generalized (GE) and 107 temporal lobe epilepsy (TLE) patients, along with 65 healthy controls. Structural and functional network profiling highlighted extensive atrophy, microstructural disruptions and decreased thalamo-cortical connectivity in TLE, while GE showed only subtle structural anomalies paralleled by enhanced thalamo-cortical connectivity. Connectome-informed biophysical simulations indicated modest increases in subcortical drive contributing to cortical dynamics in GE, while TLE presented with reduced subcortical drive and imbalanced excitation–inhibition within limbic and somatomotor microcircuits. Multiple sensitivity analyses supported robustness. Our multiscale analyses differentiate human focal and generalized epilepsy at the systems-level, showing paradoxically more severe microcircuit and macroscale imbalances in the former.
A nitroreductase and glutathione responsive nanoplatform for integration of gene delivery and near-infrared fluorescence imaging
Authors: Liang Hong , Bi Qunjie , Hu Ao , Chen Xiaobing , Jin Rongrong , Song Xu , Ke Bowen , Barz Matthias , Nie Yu
Published: May 2020

A novel platform rationally integrating indocyanine green analogues and an arginine-rich dendritic peptide with both nitroreductase (NTR) and glutathione (GSH) reduction responsive linkers was developed.
Total synthesis study of rauvomines A and B: construction of the pentacyclic core structure
Authors: Wu Binglu , Jiang Zhi-Jiang , Tang Jianbo , Gao Zhanghua , Liang Hongze , Tang Bencan , Chen Jia , Lei Kewei
Published: May 2020

The fifth ring of rauvomines can be annulatedviaa Mukaiyama-Aldol reaction as a new strategy for sarpagine scaffold construction.
A mathematical finance approach to the stochastic and intermittent viscosity fluctuations in living cells
Authors: Bostoen Claude L. , Berret Jean-François
Published: May 2020

Here we report on the viscosity of eukaryotic living cells, as a function of time, and on the application of stochastic models to analyze its temporal fluctuations.
Highly efficient enrichment ofN-glycopeptides by two-dimensional Hf-based metal–organic framework nanosheets
Authors: Yang Shi-Shu , Wang Chen , Xiao Jing , Yu Xizhong , Shang Wenbin , Chen David Da Yong , Gu Zhi-Yuan
Published: May 2020

2-D Hf-BTB nanosheets were explored as efficient materials for the capture of glycopeptides from the biosamples in proteomics analysis.
Analysis of subcutaneous swine fat via deep Raman spectroscopy using a fiber-optic probe
Authors: Kang Jeon Woong , Lim Soo Yeong , Galindo Luis H. , Yoon Hongman , Dasari Ramachandra R. , So Peter T. C. , Kim Hyung Min
Published: May 2020

Since the fat content of pork is a deciding factor in meat quality grading, the use of a noninvasive subcutaneous probe for real-time in situ monitoring of the fat components is of importance to vendors and other interested parties.
Regioselective synthesis and anticancer evaluation of H2O2-activable nucleosides
Authors: Sun Ying-Jie , Liu Li , Cheng Liang
Published: May 2020

We reported herein the design and synthesis of H2O2-activatable nucleosides via an efficient synthesis and their biological evaluation against cancer cells.
Ultrastable hydrido gold nanoclusters with the protection of phosphines
Authors: Yuan Shang-Fu , Li Jiao-Jiao , Guan Zong-Jie , Lei Zhen , Wang Quan-Ming
Published: May 2020

Two phosphine-protected gold nanoclusters with an unprecedented hetero superatomic Au20 core have been isolated. The presence of hydrides is evidenced by mass spectrometry and NMR spectroscopy.
Highest-Tc organic enantiomeric ferroelectrics obtained by F/H substitution
Authors: Ai Yong , Wu Dong-Ji , Yang Meng-Juan , Wang Pan , He Wen-Hui , Liao Wei-Qiang
Published: May 2020

(R)- and (S)-(N,N-dimethyl-3-fluoropyrrolidinium) iodide show the highest phase transition temperature (Tc) of 470 K among enantiomeric ferroelectrics.
Tetrachloroplatinate(ii) anion as a square-planar tecton for crystal engineering involving halogen bonding
Authors: Suslonov Vitalii V. , Eliseeva Anastasiya A. , Novikov Alexander S. , Ivanov Daniil M. , Dubovtsev Alexey Yu. , Bokach Nadezhda A. , Kukushkin Vadim Yu.
Published: May 2020

The tetrachloroplatinate(ii) anion behaves as a useful XB-accepting tecton toward sigma-hole-donating organohalide species.
Band engineering of mesoporous TiO2 with tunable defects for visible-light hydrogen generation
Authors: Yan Jin , Dai Lei , Shi Penghui , Fan Jinchen , Min Yulin , Xu Qunjie
Published: May 2020

A limited light absorption range and low electron transfer efficiency have always been the major problems in semiconductor photocatalysis.
Relating circular dichroism to atomic structure by means of MD simulations and computed CD spectra with α-peptoids as an example
Authors: Bhattacharjee Nicholus , Perrin Lionel , Jolibois Franck
Published: May 2020

Accurate TD-DFT calculations of electronic circular dichroism have been performed to characterise the 3D structure of α-peptoids.
Energetics and structures of the tilted phases of fatty acid Langmuir monolayers
Authors: Toledano Óscar , Rubio Miguel A. , Gálvez Óscar
Published: May 2020

Langmuir monolayers are monomolecular deep films composed of amphiphilic molecules which are typically confined to a water/air interface in a bi-dimensional structure.
Reaction mechanism of N-cyclopropylglycine oxidation by monomeric sarcosine oxidase
Authors: Shoji Mitsuo , Abe Yukihiro , Boero Mauro , Shigeta Yasuteru , Nishiya Yoshiaki
Published: May 2020

Reaction mechanism of monomeric sarcosine oxidase (MSOX) with N-cyclopropylglycine (CPG) is unravelled at the theoretical level of the hybrid quantum mechanics/molecular mechanical (QM/MM) method.
Proton affinities of pertechnetate (TcO4−) and perrhenate (ReO4−)
Authors: Jian Jiwen , Varathan Elumalai , Cheisson Thibault , Jian Tian , Lukens Wayne W. , Davis Rebecca L. , Schelter Eric J. , Schreckenbach Georg , Gibson John K.
Published: May 2020

Endeavoring to understand the basis for the difference between proton affinities of pertechnetate and perrhenate anions reveals complexity in a seemingly straightforward phenomenon.
The role of boron sites in side-chain alkylation of toluene with methanol and a high performance composite catalyst
Authors: Li Peidong , Han Qiao , Yuan Yangyang , Zhang Xiaomin , Guo Hongchen , Xu Lei
Published: May 2020

A method and key factors for preparing high performance catalysts for side-chain alkylation of toluene with methanol were developed and proposed.
Tuning the reactivity of molybdenum (oxy)carbide catalysts by the carburization degree: CO2 reduction and anisole hydrodeoxygenation
Authors: Zhu Jiadong , Uslamin Evgeny A. , Kosinov Nikolay , Hensen Emiel J. M.
Published: May 2020

Structure-performance relations for molybdenum (oxy)carbide catalysts evaluated for CO2 hydrogenation and anisole hydrodeoxygenation.
Intercalation of Nb2O5 nano-flowers into the walls of few-layer black phosphorus creating a heterostructure of FL-BP@Nb2O5 with the potential for environmental application
Authors: Bhembe Yoliswa Anittah , Lukhele Lungile Patricia , Sinha Ray Suprakas , Dlamini Langelihle Nsikayezwe
Published: May 2020

Herein we report the successful exfoliation of few-layer BP (FL-BP) from bulk BP via ultrasonication in N-methylpyrrolidone (NMP).
Spectroscopic characterization of a new Re(i) tricarbonyl complex with a thiosemicarbazone derivative: towards sensing and electrocatalytic applications
Authors: Souza Breno L. , Faustino Leandro A. , Prado Fernando S. , Sampaio Renato N. , Maia Pedro I. S. , Machado Antonio Eduardo H. , Patrocinio Antonio Otavio T.
Published: May 2020

A novel Re(i) complex with a thiosemicarbazone derivative is described and fully characterized. Its was further explored as CO2reduction electrocatalyst, being the first complex with a thiosemicarbazone derivative applied to this goal.
A comparison between whole mung bean and decorticated mung bean: beneficial effects on the regulation of serum glucose and lipid disorders and the gut microbiota in high-fat diet and streptozotocin-induced prediabetic mice
Authors: Hou Dianzhi , Zhao Qingyu , Yousaf Laraib , Chen Borui , Xue Yong , Shen Qun
Published: May 2020

This study aimed to investigate the beneficial effects of whole and decorticated mung beans on the regulation of serum glucose and lipid disorders in HFD/STZ-induced prediabetic mice, and to further explore their gut microbiota modulatory effects.
Electrochemical and direct C–H methylthiolation of electron-rich aromatics
Authors: Wu Yaxing , Ding Hongliang , Zhao Ming , Ni Zhong-Hai , Cao Jing-Pei
Published: May 2020

The electrochemical-induced C–H methylthiolation of electron-rich aromatics has been accomplished via a three component cross-coupling strategy.
High enhancement of the hydrolysis rate of cellulose after pretreatment with inorganic salt hydrates
Authors: Lara-Serrano Marta , Morales-delaRosa Silvia , Campos-Martín Jose M. , Fierro Jose L. G.
Published: May 2020

Cellulose treatment dissolution/precipitation in inorganic salt hydrates produces a dramatic morphology change that yields a reactivity improvement respect the untreated for transformations.
Chromatographic purification of antimony for accurate isotope analysis by MC-ICP-MS
Authors: Liu Jianfeng , Chen Jiubin , Zhang Ting , Wang Yina , Yuan Wei , Lang Yunchao , Tu Chenglong , Liu Liangzhi , Birck Jean-Louis
Published: May 2020

A new purification approach is reported for the highly precise and accurate determination of Sb isotope ratios in geological samples.
Self-aligned 3D microlenses in a chip fabricated with two-photon stereolithography for highly sensitive absorbance measurement
Authors: Tang Jiukai , Qiu Guangyu , Cao Xiaobao , Yue Yang , Zhang Xiaole , Schmitt Jean , Wang Jing
Published: May 2020

3D microlenses (in plane) via mold replication were incorporated in the microfluidic chip for improving the performance of absorbance measurements.
Polyoxometalates function as indirect activators of a G protein-coupled receptor
Authors: Althumairy Duaa , Postal Kahoana , Barisas B George , Nunes Giovana G , Roess Deborah A , Crans Debbie C
Published: May 2020

The luteinizing hormone receptor (LHR), a G protein-coupled receptor (GPCRs), can initiate signaling in the presence of some vanadium-containing compounds as a result of vanadium compound interactions with the membrane lipids and/or the cell membrane lipid interface. The ability of LHR expressed in CHO cells to initiate signaling in the presence of highly charged and water-soluble polyoxovanadates (POV) including Na3[H3V10O28] (V10) and two mixed-valence heteropolyoxovanadates, K(NH4)4[H6V14O38(PO4)]·11H2O (V14) and [(CH3)4N]6[V15O36(Cl)] (V15), was investigated here. Interactions of the vanadium compounds with CHO cells decreased the packing of membrane lipids, drove aggregation of LHR and increased signal transduction by LHR. Cell responses were comparable to, or in the case of V14 and V15, greater than those seen for cells treated with human chorionic gonadotropin (hCG), a naturally-occurring LHR ligand produced in early pregnancy in humans. POV effects were observed for CHO cells where LHR was expressed at 10 000 or 32 000 LHR per cell but not when LHR was overexpressed with receptor numbers >100 000 LHR per cell. To determine which POV species were present in the cell medium during cell studies, the speciation of vanadate (V1), V10, V14 or V15 in cell medium was monitored using 51V NMR and EPR spectroscopies. We found that all the POVs initiated signaling, but V15 and V10 had the greatest effects on cell function, while V1 was significantly less active. However, because of the complex nature of vanadium compounds speciation, the effects on cell function may be due to vanadium species formed in the cell medium over time.
Simulation of self-heating process on the nanoscale: a multiscale approach for molecular models of nanocomposite materials
Authors: Donati Greta , De Nicola Antonio , Munaò Gianmarco , Byshkin Maksym , Vertuccio Luigi , Guadagno Liberata , Le Goff Ronan , Milano Giuseppe
Published: May 2020

We develop a theoretical–computational protocol to simulate Joule heating on nanocomposite materials, allowing to investigate morphology, voltage and concentration effects.
Beam generation and structural optimization of size-selected Au923 clusters
Authors: Lu Siqi , Hu Kuojuei , Zuo Zewen , Hu Shengyong , Wang Guanghou , Song Fengqi , Cao Lu
Published: May 2020

We show the feasibility to control the structure of gold cluster Au923 in a large range.
Study of the influence of intermolecular interaction on classical and reverse substituent effects inpara-substituted phenylboranes
Authors: Jabłoński Mirosław , Krygowski Tadeusz M.
Published: May 2020

The substituent effect and the reverse substituent effect inpara-substituted phenylboranes and the influence of the intermolecular interaction of H⋯B type with either silane or methylsilane on the latter of these effects are extensively studied.
Dinuclear complexes of Mn, Co, Zn and Cd assembled with 1,4-cyclohexanedicarboxylate: synthesis, crystal structures and acetonitrile fluorescence sensing properties
Authors: Rosales-Vázquez Luis D. , Martínez-Otero Diego , Sánchez-Mendieta Víctor , Jaramillo-García Jonathan , Téllez-López Antonio , Escudero Roberto , Morales Francisco , Valdes-García Josue , Dorazco-González Alejandro
Published: May 2020

Selective and reversible fluorescence sensing of acetonitrile in water by [Cd2(H2O)2(chdc)2(bipy)2]·H2O with a detection limit of 1.1 × 10−6 M.
Enhanced UV stability of N-halamine-immobilized Fe3O4@SiO2@TiO2 nanoparticles: synthesis, characteristics and antibacterial property
Authors: Bu Danlin , Li Na , Zhou Yu , Feng Hengyu , Yu Fei , Cheng Chunxia , Li Ming , Xiao Linghan , Ao Yuhui
Published: May 2020

Recycling of N-halamine-modified Fe3O4@SiO2@TiO2 antibacterial materials with UV stability.
A new Dirac nodal-ring semimetal made of 3D cross-linked graphene networks as lithium ion battery anode materials
Authors: Wang Shuaiwei , Peng Zhilong , Fang Daining , Chen Shaohua
Published: May 2020

A Dirac nodal-ring semimetal made of cross-linked graphene networks for use as an anode material in lithium ion batteries.
2D materials beyond graphene toward Si integrated infrared optoelectronic devices
Authors: Lan Changyong , Shi Zhe , Cao Rui , Li Chun , Zhang Han
Published: May 2020

A study of typical 2D materials beyond graphene suitable for infrared applications, in particular, infrared light emitting devices, optical modulators, and photodetectors.
Nanofabrication within unimolecular nanoreactors
Authors: Wang Youfu , Zhu Xinyuan
Published: May 2020

This review presents nanoparticles with delicate and expected nanofeatures fabricated within various unimolecular nanoreactors with stable and designable nanostructures.
A green strategy for the preparation of a honeycomb-like silicon composite with enhanced lithium storage properties
Authors: Gao Runsheng , Tang Jie , Yu Xiaoliang , Zhang Kun , Ozawa Kiyoshi , Qin Lu-Chang
Published: May 2020

A honeycomb-like silicon–carbon composite electrode was prepared via a green nascent hydrogen method to achieve enhanced lithium storage properties.
Meisenheimer complexes as hidden intermediates in the aza-SNAr mechanism
Authors: Ormazábal-Toledo Rodrigo , Richter Sebastián , Robles-Navarro Andrés , Maulén Boris , Matute Ricardo A. , Gallardo-Fuentes Sebastián
Published: May 2020

In this work we report a computational study about the aza-SNAr mechanism in fluorine- and chlorine-containing azines with the aim to unravel the physical factors that determine the reactivity patterns in these heterocycles towards propylamine.
Cu-Photoredox-catalyzed C(sp)–C(sp3) coupling of redox-active esters with terminal alkynes
Authors: Zhang Yajing , Zhang Dayong
Published: May 2020

Under mild condition, redox-active esters of carboxylic acids reacted with aryl and alkyl substituted alkynes in good yields. A copper-acetylid-ligand is a key intermediate for constructing C(sp)–C(sp3) bond.
Thickness effect on VOC sensing properties of sprayed In2S3 films
Authors: Souissi R. , Bouguila N. , Bouricha B. , Vázquez-Vázquez C. , Bendahan M. , Labidi A.
Published: May 2020

The dynamic response of In2S3 films to 4000 ppm of methanol, ethanol and acetone at 350 °C for thicknesses varying from 0.8 μm to 6.1 μm.
An anti-leakage liquid metal thermal interface material
Authors: Huang Kaiyuan , Qiu Wangkang , Ou Meilian , Liu Xiaorui , Liao Zenan , Chu Sheng
Published: May 2020

An improved form of LM/indium film/LM sandwich pad with surface micropillar arrays is a high-performance thermal interface material for thermal management.
Shampoo assisted aligning of carbon nanotubes toward strong, stiff and conductive fibers
Authors: Wang Jiaojiao , Zhao Jingna , Qiu Lin , Li Fengcheng , Xu Changle , Wu Kunjie , Wang Pengfei , Zhang Xiaohua , Li Qingwen
Published: May 2020

Entangled carbon nanotubes can be effectively aligned by introducing a lubricating agent, as inspired by the life experience of hair detangling.
Anomalous transport and magnetic properties induced by slight Cu valence alternation in layered oxytelluride BiCuTeO
Authors: Luo Ye-Cheng , Lin Dajun , Zhang Yan-Yan , Dong Song-Tao , Yao Shu-Hua , Lv Yang-Yang , Zhou Jian , Chen Y. B.
Published: May 2020

A nonlinear Hall effect and weak antiferromagnetism are induced by mixed-valence Cu in BiCuTeO.
Recent applications of ninhydrin in multicomponent reactions
Authors: Das Suven
Published: May 2020

This article aims to review recent multicomponent reactions of ninhydrin towards diverse organic scaffolds, such as indeno-fused heterocycles, spiro-indeno heterocycles, quinoxalines, propellanes, cage-like compounds, and dispiro heterocycles.
Isosorbide bis(methyl carbonate) synthesis from isosorbide and dimethyl carbonate: the key role of dual basic–nucleophilic catalysts
Authors: Ochoa-Gómez José R. , Lorenzo-Ibarreta Leire , Diñeiro-García Cristina , Gómez-Jiménez-Aberasturi Olga
Published: May 2020

Basic–nucleophilic nitrogenated organocatalysts catalyze the synthesis of isosorbide bis(methyl carbonate), with nucleophilicity having an influence twice as much as basicity on catalytic activity.
Light-harvesting complexes access analogue emissive states in different environments
Authors: Mascoli Vincenzo , Gelzinis Andrius , Chmeliov Jevgenij , Valkunas Leonas , Croce Roberta
Published: May 2020

Photosynthetic antennae regulate the level of excitations in the membrane by tuning their excited state properties. Here we show that the antennae access the same light-harvesting and dissipative states in different in vitro environments.
Surface engineering of earth-abundant Fe catalysts for selective hydrodeoxygenation of phenolics in liquid phase
Authors: Zhang Jianghao , Sun Junming , Kovarik Libor , Engelhard Mark H. , Du Lei , Sudduth Berlin , Li Houqian , Wang Yong
Published: May 2020

Tailoring the graphene-covered Fe with Cs modifies the surface electronic properties of the catalysts such that selective C–O bond cleavage of phenol is achieved in liquid phase by inhibiting the facile tautomerization followed by ring saturation.
A boronic acid-functionalized phthalocyanine with an aggregation-enhanced photodynamic effect for combating antibiotic-resistant bacteria
Authors: Lee Eunhye , Li Xingshu , Oh Juwon , Kwon Nahyun , Kim Gyoungmi , Kim Dongho , Yoon Juyoung
Published: May 2020

A boronic acid functionalized phthalocyanine displays aggregation-enhanced reactive oxygen species (ROS) generation and excellent photodynamic antibacterial activity.
Fulvalene as a platform for the synthesis of a dimetallic dysprosocenium single-molecule magnet
Authors: He Mian , Guo Fu-Sheng , Tang Jinkui , Mansikkamäki Akseli , Layfield Richard A.
Published: May 2020

A series of fulvalene-supported dimetallic dysprosium metallocene SMMs provides a roadmap to poly-cationic dysprosocenium single-molecule magnets.
Enantio- and diastereoselective conjugate borylation/Mannich cyclization
Authors: Larin Egor M. , Loup Joachim , Polishchuk Iuliia , Ross Rachel J. , Whyte Andrew , Lautens Mark
Published: May 2020

Copper-catalyzed enantio- and diastereoselective conjugate borylation across Michael acceptors, with subsequent Mannich-type cyclization, was utilized to construct tetrahydroquinoline scaffolds containing three contiguous stereocenters.
Highly porous Ti–Ni anodes for electrochemical oxidations
Authors: Guenani Nihal , Barawi Mariam , Villar-García Ignacio J. , Bisquert Juan , de la Peña O'Shea Víctor A. , Guerrero Antonio
Published: May 2020

Powder metallurgy enables the fabrication of scalable and efficient electrodes for oxidation reactions.
A fundamental study of the thermoelectrochemistry of ferricyanide/ferrocyanide: cation, concentration, ratio, and heterogeneous and homogeneous electrocatalysis effects in thermogalvanic cells
Authors: Buckingham Mark A. , Hammoud Samer , Li Huanxin , Beale Conor J. , Sengel Jason T. , Aldous Leigh
Published: May 2020

Thermocells can sustainably generate electricity from waste heat temperature gradients. This study investigates numerous fundamental aspects of thermocells, and how to explain and model such aspects.
Integrating anaerobic digestion and slow pyrolysis improves the product portfolio of a cocoa waste biorefinery
Authors: Ghysels Stef , Acosta Nayaret , Estrada Adriana , Pala Mehmet , De Vrieze Jo , Ronsse Frederik , Rabaey Korneel
Published: May 2020

Integrating anaerobic digestion/slow pyrolysis of agricultural residues (cocoa waste) resulted in biogas, biochar and phenolics-rich pyrolysis liquids of superior quality.
S-Doped Ni(OH)2 nano-electrocatalyst confined in semiconductor zeolite with enhanced oxygen evolution activity
Authors: Hu Dandan , Wang Xiang , Chen Xitong , Wang Yanxiang , Hong Anh N. , Zhong Jun , Bu Xianhui , Feng Pingyun , Wu Tao
Published: May 2020

Fluoride-assisted in situ confinement of S-doped Ni(OH)2 nanoelectrocatalyst in semiconductor zeolite for enhanced oxygen evolution activity.
Naphthalene diimide as a two-electron anolyte for aqueous and neutral pH redox flow batteries
Authors: Medabalmi Veerababu , Sundararajan Mahesh , Singh Vikram , Baik Mu-Hyun , Byon Hye Ryung
Published: May 2020

The potassium salt of N,N′-bis(glycinyl)naphthalene diimide [K2-BNDI] showed stable two-electron redox reactions accompanied by ion-pairing in aqueous redox-flow batteries.
Facet engineering of LaNbON2 transformed from LaKNaNbO5 for enhanced photocatalytic O2 evolution
Authors: Wang Xin , Hisatomi Takashi , Liang Junwu , Wang Zheng , Xiang Yuanjiang , Zhao Yihua , Dai Xiaoyu , Takata Tsuyoshi , Domen Kazunari
Published: May 2020

Matching crystal structures allowed the generation of an active LaNbON2 photocatalyst with exposed metastable {010} facets from plate-like LaKNaNbO5.
3D confined zinc plating/stripping with high discharge depth and excellent high-rate reversibility
Authors: Zhou Yurong , Wang Xiaona , Shen Xiaofan , Shi Yanhong , Zhu Chengfeng , Zeng Sha , Xu Hao , Cao Pei , Wang Yulian , Di Jiangtao , Li Qingwen
Published: May 2020

Confining Zn plating and stripping in a robust and conductive 3D carbon nanotube network results in an electrode, which shows excellent reversibility at high depth of discharge and enables zinc-ion batteries with high-rate and long-term performance.
Deregulation of miRNAs-cMYC circuits is a key event in refractory celiac disease type-2 lymphomagenesis
Authors: Vaira Valentina , Gaudioso Gabriella , Laginestra Maria Antonella , Terrasi Andrea , Agostinelli Claudio , Bosari Silvano , Di Sabatino Antonio , Vanoli Alessandro , Paulli Marco , Ferrero Stefano , Roncoroni Leda , Lombardo Vincenza , Perera Liyanage P. , Fabris Sonia , Vecchi Maurizio , Pileri Stefano , Elli Luca
Published: May 2020

A percentage of celiac disease (CD) patients develop refractory type-2 disease (RCD2), a condition associated with increased risk of enteropathy-associated T-cell-lymphoma (EATL) and without therapeutic option. Therefore, we profiled the miRNome in series of peripheral T-cell lymphomas (PTCLs), CD, RCD1 or 2 and in the murine interleukin-15 (IL15)-transgenic (TG) model of RCD. The transcriptome was analyzed in 18 intestinal T-cell lymphomas (ITLs). Bioinformatics pipelines provided significant microRNA (miRNA) lists and predicted targets that were confirmed in a second set of patients.

Our data show that ITLs have a unique miRNA profile with respect to other PTCLs. The c-MYC regulated miR-17/92 cluster distinguishes monomorphic epitheliotropic ITL (MEITL) from EATL and prognosticates EATL outcome. These miRNAs are decreased in IL15-TG mice upon Janus kinase (JAK) inhibition. The random forest algorithm identified a signature of 38 classifier miRNAs, among which, the miR-200 and miR-192/215 families were progressively lost in RCD2 and ITL-CD, whereas miR-17/92 and C19MC miRNAs were up-regulated. Accordingly, SMAD3, MDM2, c-Myc and activated-STAT3 were increased in RCD2 and EATL tissues while JAK inhibition in IL15-TG mice restored their levels to baseline.

Our data suggest that miRNAs circuit supports activation of STAT3 and c-Myc oncogenic signaling in RCD2, thus contributing to lymphomagenesis. This novel understanding might pave the way to personalized medicine approaches for RCD and EATL.
Capture of satellites during planetary encounters
Authors: Li Daohai , Johansen Anders , Mustill Alexander J. , Davies Melvyn B. , Christou Apostolos A.
Published: May 2020

Context.Single-binary scattering may lead to an exchange where the single object captures a component of the binary, forming a new binary. This has been well studied in encounters between a star–planet pair and a single star.

Aims.Here we explore the application of the exchange mechanism to a planet–satellite pair and another planet in the gravitational potential of a central star. As a case study, we focus on encounters between a satellite-bearing object and Neptune. We investigate whether Neptune can capture satellites from that object and if the captured satellites have orbits analogous to the Neptunian moons Triton and Nereid.

Methods.UsingN-body simulations, we study the capture probability at different encounter distances. Post-capture, we use a simple analytical argument to estimate how the captured orbits evolve under collisional and tidal effects.

Results.We find that the average capture probability reaches ~10% if Neptune penetrates the donor planet’s satellite system. Most moons grabbed by Neptune acquire highly eccentric orbits. Post-capture, around half of those captured, especially those on tight orbits, can be circularised, either by tides only or by collisions+tides, turning into Triton-like objects. Captures further out, on the other hand, stay on wide and eccentric orbits like that of Nereid. Both moon types can be captured in the same encounter and they have wide distributions in orbital inclination. Therefore, Triton naturally has a ~50% chance of being retrograde.

Conclusions.A similar process potentially applies to an exoplanetary system, and our model predicts that exomoons can jump from one planet to another during planetary scattering. Specifically, there should be two distinct populations of captured moons: one on close-in circular orbits and the other on far-out eccentric orbits. The two populations may have highly inclined prograde or retrograde orbits.
Case study of multi-temperature coronal jets for emerging flux MHD models
Authors: Joshi Reetika , Chandra Ramesh , Schmieder Brigitte , Moreno-Insertis Fernando , Aulanier Guillaume , Nóbrega-Siverio Daniel , Devi Pooja
Published: May 2020

Context. Hot coronal jets are a basic observed feature of the solar atmosphere whose physical origin is still actively debated.

Aims. We study six recurrent jets that occurred in active region NOAA 12644 on April 4, 2017. They are observed in all the hot filters of AIA as well as cool surges in IRIS slit–jaw high spatial and temporal resolution images.

Methods. The AIA filters allow us to study the temperature and the emission measure of the jets using the filter ratio method. We studied the pre-jet phases by analysing the intensity oscillations at the base of the jets with the wavelet technique.

Results. A fine co-alignment of the AIA and IRIS data shows that the jets are initiated at the top of a canopy-like double-chambered structure with cool emission on one and hot emission on the other side. The hot jets are collimated in the hot temperature filters, have high velocities (around 250 km s−1) and are accompanied by cool surges and ejected kernels that both move at about 45 km s−1. In the pre-phase of the jets, we find quasi-periodic intensity oscillations at their base that are in phase with small ejections; they have a period of between 2 and 6 min, and are reminiscent of acoustic or magnetohydrodynamic waves.

Conclusions. This series of jets and surges provides a good case study for testing the 2D and 3D magnetohydrodynamic emerging flux models. The double-chambered structure that is found in the observations corresponds to the regions with cold and hot loops that are in the models below the current sheet that contains the reconnection site. The cool surge with kernels is comparable with the cool ejection and plasmoids that naturally appears in the models.
The GAPS programme at TNG
Authors: Benatti S. , Damasso M. , Desidera S. , Marzari F. , Biazzo K. , Claudi R. , Di Mauro M. P. , Lanza A. F. , Pinamonti M. , Barbato D. , Malavolta L. , Poretti E. , Sozzetti A. , Affer L. , Bignamini A. , Bonomo A. S. , Borsa F. , Brogi M. , Bruno G. , Carleo I. , Cosentino R. , Covino E. , Frustagli G. , Giacobbe P. , Gonzalez M. , Gratton R. , Harutyunyan A. , Knapic C. , Leto G. , Lodi M. , Maggio A. , Maldonado J. , Mancini L. , Martinez Fiorenzano A. , Micela G. , Molinari E. , Molinaro M. , Nardiello D. , Nascimbeni V. , Pagano I. , Pedani M. , Piotto G. , Rainer M. , Scandariato G.
Published: May 2020

Context. Observations of exoplanetary systems demonstrate that a wide variety of planetary architectures are possible. Determining the rate of occurrence of Solar System analogues – with inner terrestrial planets and outer gas giants – remains an open question.

Aims. Within the framework of the Global Architecture of Planetary Systems (GAPS) project, we collected more than 300 spectra with HARPS-N at the Telescopio Nazionale Galileo for the bright G9V star HD 164922. This target is known to host one gas giant planet in a wide orbit (Pb ~1200 days, semi-major axis ~ 2 au) and a Neptune-mass planet with a period of Pc ~76 days. We aimed to investigate the presence of additional low-mass companions in the inner region of the system.

Methods. We compared the radial velocities (RV) and the activity indices derived from the HARPS-N time series to measure the rotation period of the star and used a Gaussian process regression to describe the behaviour of the stellar activity. We then combined a model of planetary and stellar activity signals in an RV time series composed of almost 700 high-precision RVs, both from HARPS-N and literature data. We performed a dynamical analysis to evaluate the stability of the system and the allowed regions for additional potential companions. We performed experiments on the injection and recovery of additional planetary signals to gauge the sensitivity thresholds in minimum mass and orbital separation imposed by our data.

Results. Thanks to the high sensitivity of the HARPS-N dataset, we detected an additional inner super-Earth with an RV semi-amplitude of 1.3 ± 0.2 m s−1 and a minimum mass of md sin i = 4 ± 1 M⊕. It orbits HD 164922 with a period of 12.458 ± 0.003 days. We disentangled the planetary signal from activity and measured a stellar rotation period of ~ 42 days. The dynamical analysis shows the long-term stability of the orbits of the three-planet system and allows us to identify the permitted regions for additional planets in the semi-major axis ranges 0.18–0.21 au and 0.6–1.4 au. The latter partially includes the habitable zone of the system. We did not detect any planet in these regions, down to minimum detectable masses of 5 and 18 M⊕, respectively. A larger region of allowed planets is expected beyond the orbit of planet b, where our sampling rules out bodies with minimum mass >50 M⊕. The planetary orbital parameters and the location of the snow line suggest that this system has been shaped by a gas disk migration process that halted after its dissipation.
Re-augmentation of the Axilla Using a Turn-Over Flap – a New Approach for the Surgical Treatment of Secondary Lymphedema After Breast Cancer
Authors: Marx Mario , Geßner Michael , Florek Alexander , Morgenstern Susanne , Passin Stefan , Brucker Sara Y. , Wallwiener Diethelm , Hahn Markus
Published: May 2020

Introduction Scarring and volume reduction of the axillary space resulting in persistent lymphedema is a side effect of axillary treatment in breast cancer patients. The aim of this paper is to describe the reduction of lymphedema achieved with a turnover flap.

Materials and Methods Between October 2016 and May 2018, five patients with grade 2 lymphedema following breast cancer therapy underwent reconstructive surgery with a turnover flap. Complete excision of the symptomatic axillary scar tissue followed by re-augmentation using a turnover flap was performed. Subsequently, all patients underwent breast reconstruction using a distant flap reconnected to the thoracodorsal vessels. The circumference of both arms, quality of life and pain were measured before and after surgery.

Results An average reduction in pain in the ipsilateral arm from 6 to 1 on the numerical scale as well as an improvement in quality of life (2.8 vs. 7.0) was observed. A decrease in lymphedema especially in the upper arm was identified. No complications such as secondary bleeding, infections or flap loss were observed.

Conclusion Complete removal of the axillary scar tissue after breast cancer treatment and re-augmentation of the axilla with a turnover flap results in a reduction in ipsilateral lymphedema and an improvement in pain and quality of life. We interpret these findings as a result of the physiological re-alignment of the lymphatic vessels combined with a lymph node-containing local transposition flap. Therefore, re-augmentation with a turnover flap could be an effective non-microsurgical alternative to lymph node transplantation.
Revision Arthroplasty with Total Femur Replacement for the Management of Complex Post-traumatic Bone Defect in a Patient with Dwarfism
Authors: Lausmann Christian , Niculescu Stefan , Citak Mustafa , Rossmann Markus , Gehrke Thorsten , Zahar Akos
Published: May 2020

Dwarfism leads to an early onset of osteoarthritis of the joints of the lower limb. Due to bone deformities, arthroplasty is challenging. The incidence of implant-associated complications is higher compared to the normal population and often ends up with multiple revision arthroplasties. We report the first case in the literature of a 48-year-old patient with dwarfism who required implantation of a custom-made total femoral replacement due to aseptic stem loosening and a concomitant valgus gonarthrosis.