bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan antara Gula Darah Sewaktu dan Faal Paru pada Pasien Diabetes Melitus di Puskesmas Jumpandang Baru Makassar
Authors: Shavira MD  , Dwi Anggita  , Khalid Nur Fadhillah , Wiriansya Edward Pandu , Yani Sodiqah  , Hasan  , Happy Laurentz
Published: March 2024

Latar belakang: Hiperglikemi kronik dapat menimbulkan hambatan proses pertukaran O2 dan CO2 di paru akibat adanya penumpukan protein berupa kolagen di pembuluh darah. Sehingga kecepatan difusi alveoli pada paru pasien diabetes akan berkurang. Tujuan: Penelitian ini bertujuan mengetahui hubungan antara gula darah sewaktu dan faal paru pada pasien DM di Puskesmas Jumpandang Baru Makassar April-Mei 2019. Metode: Penelitian ini menggunakan desain analitik korelatif kategori, dengan pendekatan cross sectional. Sampel dalam penelitian ini adalah pasien diabetes melitus sebanyak 32 orang yang memenuhi kriteria inklusi dan eksklusi. Teknik sampling yang digunakan adalah accidental sampling. Alat ukur yang digunakan adalah alat ukur berat badan, alat ukur tinggi badan, alat ukur gula darah Autocheck dan spirometer BTL 08 MT Plus. Hasil : Dari 32 subjek penelitian didapatkan sampel kadar gula darah sewaktu tinggi dengan derajat derajat restrictive severe sebesar 80% (8 dari 10  responden), dan derajat restrictive moderate sebesar 20% (2 dari 10 responden) sedangkan pasien diabetes melitus yang kadar gula darah sewaktunya rendah dengan derajat restrictive severe sebesar 32% (7 dari 22 responden), derajat restrictive moderate 36% (8 dari 22  responden), derajat restrictive mild sebesar 5% ( 1 dari 22 responden), serta dalam keadaan faal paru normal sebesar 27% ( 6 dari 22 responden). Kesimpulan: Berdasarkan hasil uji Chi-Square menunjukkan tidak ada hubungan yang signifikan antara kadar gula darah sewaktu dengan kapasitas vital paru pada pasien diabetes mellitus (nilai p=0.067).
Hubungan Asupan Karbohidrat Ibu Hamil Trimester III dengan BB Lahir Bayi RSIA Kota Makassar
Authors: Marhamah  , Nesyana Nurmadilla  , Sigit Dwi Pramono  , Fadli Ananda  , Rasfayanah
Published: March 2024

Gizi ibu yang kurang pada saat kehamilan akan menghambat pertumbuhan dan perkembangan janin, serta menghambat pembentukan fungsi otak janin. Janin yang kekurangan gizi berisiko lahir dengan berat badan rendah dan ketika tumbuh dewasa akan berisiko lebih tinggi untuk menderita penyakit degeneratif (diabetes, hipertensi, penyakit jantung, dan stroke) daripada yang tidak kekurangan gizi. Penelitian ini bertujuan untuk mengetahui bagaimana hubungan asupan karbohidrat pada ibu hamil trimester III dengan berat badan lahir bayi di RSIA Sitti Khadijah 1 dan RSIA Masyita Kota Makassar. Penelitian ini menggunakan desain analitik dengan pendekatan kohort prospektif. Sampel dalam penelitian ini adalah ibu hamil trimester III sebanyak 24 orang yang memenuhi kriteria inklusi dan eksklusi. Teknik sampling yang digunakan adalah total sampling. Alat ukur yang digunakan adalah alat ukur berat badan, alat ukur tinggi badan, pita LiLA, semi quantitative food frequency questionnaire (SF FFQ), dan timbangan bayi. Hasil penelitian pada 24 sampel ibu hamil didapatkan bahwa asupan karbohidrat kurang 12 sampel (50%), asupan karbohidrat cukup 7 sampel (29,2%) dan asupan karbohidrat berlebih 5 sampel (20,8 %). Untuk LiLA didapatkan 2 sampel KEK (8,3%) dan 22 tidak KEK (91,7%) dan untuk berat badan lahir bayi didapatkan BBLR 1 sampel (4,2%), berat normal 22 sampel (41,7%) dan berat berlebih 1 sampel (4,2%). Kemudian Berdasarkan hasil uji Chi-Square menunjukkan tidak ada hubungan yang signifikan antara asupan karbohidrat dengan berat badan lahir bayi dengan nilai p=0,779.
Pengaruh Intensitas Membaca Al-Qur’an terhadap Kecerdasan Emosional Mahasiswa FORSIK Fakultas Kedokteran Universitas Muslim Indonesia Angkatan 2018
Authors: Wijaya Nadya Videlia , Murfat Zulfitriani , Khalid Nur Fadhillah , Sri Julyani  , Mokhtar Shulhana , Sri Juniarty  , Akhmad Kadir  , Andi Tenrigangka
Published: March 2024

Latar Belakang: Kecerdasan emosional termasuk dalam kemampuan seseorang dalam menilai, mengontrol, dan mengelola emosi dengan baik pada diri sendiri dalam berhubungan dengan orang lain, dimana proses membaca Al-Qur’an adalah salah satu cara yang efektif dalam rangka meningkatkan kecerdasan emosional. Tujuan: Penelitian ini untuk mengetahui pengaruh intensitas membaca Al-Qur’an terhadap kecerdasan emosional mahasiswa forsik fakultas kedokteran Universitas Muslim Indonesia angkatan 2018. Metode: Jenis penelitian ini merupakan penelitian analitik observasional dengan pendekatan Cross Sectional. Hasil: Penelitian ini melibatkan 41 orang melalui pengisian kuesioner online, hasil penelitian ini menunjukkan bahwa mayoritas subjek penelitian berjenis kelamin perempuan sebanyak 27 orang (65,9%) dengan Intensitas membaca Al-Qur’an dengan kategori selalu (56,1%) dan kecerdasan emosional dengan kategori kadang mampu mengontrol emosional dengan baik (70,7%). Hasil analisis menunjukkan bahwa terdapat pengaruh intensitas membaca Al-Qur’an terhadap kecerdasan emosional mahasiswa (nilai p = 0,004; p < 0,05). Kesimpulan: Terdapat pengaruh antara intensitas membaca Al-Qur’an dengan kecerdasan emosional pada mahasiswa forsik Fakultas Kedokteran Muslim Indonesia Angkatan 2018.
Pengaruh Kebiasaan Penggunaan Headset terhadap Gangguan Telinga
Authors: Risa Hude Umar  , Shulhana Mokhtar  , Rasfayanah  , A. Tenri Sanna Arifuddin  , Pratama Ahmad Ardhani
Published: March 2024

Telinga merupakan salah satu alat panca indra pada manusia, salah satu fungsinya menerima gelombang suara yang kemudian diubah menjadi impuls listrik dan diteruskan ke otak melalui saraf pendengaran. Telinga bagian dalam mempunyai peran sebagai indra pengatur keseimbangan atau organ vestibular. Dengan meningkatnya teknologi audiovisual dan telekomunikasi saat ini, penggunaan headset untuk mendengarkan musik meningkat pada kalangan remaja. Hal itu dapat menimbulkan bising kronik serta munculnya gejala-gejala gangguan telinga seperti gatal, nyeri, terasa berdengung, yang pada akhirnya dapat mengganggu fungsi pendengaran. Penelitian ini bertujuan untuk mengetahui pengaruh kebiasaan penggunaan headset terhadap gangguan telinga dan gangguan pendengaran. Metode penelitian ini adalah literature review dengan desain narrative review. Hasil penelitian didapatkan Kebiasaan penggunaan headset terhadap gangguan telinga dan pendengaran disebabkan oleh penggunaan frekuensi dan durasi yang lebih sering sehingga pada gangguan telinga mengakibatktan gangguan nyeri dan gatal, dan pada gangguan pendengaran mengakibatkan tuli sensorineural, tuli ringan, tuli sedang, otalgia dan tinitus. Kesimpulan penelitian ini bahwa adanya pengaruh kebiasaan penggunaan headset terhadap gangguan telinga dan gangguan pendengaran.
Hubungan Tingkat Pendidikan dan Pengetahuan Ibu tentang Tumbuh Kembang Anak Usia < 6 Tahun dengan Kunjungan Ibu ke Posyandu di Kecamatan Tempe Kabupaten Wajo
Authors: Hijriah Syafitri  , Djauhariah Arifuddin  , Mona Nulanda  , Andi Husni Esa Darussalam  , Sri Wahyuni Gayatri
Published: March 2024

Pendidikandan pengetahuan ibu merupakan salah satu faktor yang mempengaruhi tumbuh kembang kembang anak. Pendidikan yang baik maka ibu dapat menerima informasi dari luar tentang cara pengasuhan anak yang baik. Kunjungan ke posyandu juga sangat berperan dalam pemantauan tumbuh kembang anak yang merupakan langkah awal untuk mencapai derajat kesehatan yang baik. Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat pendidikan dan pengetahuan ibu tentang tumbuh kembang anak usia< 6 tahun dengan kunjungan ke posyandu di Kecamatan Tempe Kabupaten Wajo. Penelitian ini adalah penelitian kuantitatif dengan mengggunakan pendekatan cross sectional untuk mengetahui hubungan tingkat pendidikan dan pengetahuan ibu tentang tumbuh kembang anak usia< 6 tahun dengan kunjungan ke posyandu. Hasil penelitian ini menunjukkan bahwa didapatkan adanya hubungan tingkat pendidikan ibu dengan kunjungan ke posyandu dengan nilai p = 0,001 < 0,05. Adanya hubungan tingkat pengetahuan ibu dengan kunjungan ke posyandu dengan nilai p = 0,000 < 0,05. Adanya hubungan tingkat pendidikan ibu terhadap tumbuh kembang anak dengan nilai p = 0,028 < 0,05. Tidak terdapat hubungan tingkat pengetahuan ibu terhadap tumbuh kembang anak dengan nilai p = 0,106 > 0,05.
Pengaruh Terapi Bekam Terhadap Kadar Kolesterol Total Pada Pasien Hiperkolesterolemia di Klinik Hamdalah Makassar
Authors: Uda'a Rizka , Dahliah  , Edward Pandu Wiriansya  , Rahmawati  , Rezky Putri Indarwati
Published: March 2024

Hiperkolesterolemia  merupakan suatu  kondisi yang dapat meningkatkan terjadinya risiko penyakit jantung koroner, stroke, tekanan darah tinggi, kegemukan dan masalah kesehatan lainnya. Mahalnya obat dan tingginya efek samping pengobatan farmakologis sehingga membutuhkan pengobatan alternatif penurunan kadar kolesterol total secara non farmakologis yaitu terapi bekam yang dianjurkan oleh Nabi Muhammad Shallallahu ‘alaihi wassalam serta seiring berjalannya waktu terapi bekam telah dimodernkan dan mengikuti kaidah ilmiah.Tujuan pada peneltian ini untuk mengetahui pengaruh terapi bekam terhadap penurunan kadar kolesterol total pada pasien hiperkolesterolemia di klinik hamdalah bekam dan ruqyah syar’iyyah kota makassar tahun 2023. Penelitian ini menggunakan pendekatan kuantitatif metode eksperimen dengan teknik total sampling berdasarkan data pasien bekam riwayat hiperkolesterolemia bulan desember 2022 dengan jumlah sampel sebanyak 36 pasien. Berdasarkan Hasil penelitian didapatkan perubahan kadar kolesterol Sebanyak 30 responden (83,3%) mengalami penurunan kadar kolesterol total setelah mengikuti terapi bekam, sedangkan 6 responden (16,7%) mengalami peningkatan kadar kolesterol total. Adanya pengaruh penurunan kadar kolesterol total yang signifikan pada pasien hiperkolesterolemia di klinik hamdalah bekam dan ruqyah syar’iyyah makassar tahun 2023.
Efek Konsumsi Kurma Ajwa (Phoenix Dactyliferal) Terhadap Kuantitas Dan Kualitas Sperma
Authors: Zhafirah Andi bayan , Andi Mappaware Nasruddin , Arfah Arni Isnaini , Ida Royani  , Kamaluddin Irna Diyana Kartika
Published: March 2024

Sperma adalah sel yang membawa DNA pasangan pria ke sel telur. Dehydroepiandrosterone (DHEA), hormon, dan testosterone, hormon, keduanya memainkan peran penting dalam produksi sperma. Pria dapat mengalami kemandulan karena berbagai sebab, salah satunya adalah kualitas spermatozoa yang buruk. Ekstrak buah kurma yang diminum telah diuji potensinya untuk meningkatkan kualitas DNA dan motilitas sperma dan dihitung menggunakan kurma yang mengandung bahan kimia fenolik dan flavonoid. Tujuan dari penelitian ini adalah untuk mengetahui apakah mengkonsumsi kurma ajwa (Phoenix dactylifera l) dapat meningkatkan produksi sperma baik secara kuantitas maupun kualitas. Memanfaatkan desain tinjauan naratif dan metodologi penelitian tinjauan literatur. Menurut penelitian yang dipublikasikan di sejumlah jurnal, mengonsumsi kurma Ajwa (Phoenix dactylifera l) dapat meningkatkan kuantitas dan kualitas sperma. Ini karena beberapa nutrisi kurma, seperti zat besi, lebih mudah diserap tubuh daripada yang ditemukan pada buah lain, dan ini, pada gilirannya, memperbaiki histopatologi sperma. Sebagai sumber energi sperma untuk melakukan perjalanan, keberadaan glukosa dan fraktosa dapat membantu motilitas sperma. Hormon dehydroepiandrosterone (DHEA) yang sangat penting untuk pembentukan sperma dapat ditingkatkan oleh kandungan fenolik dan flavonoid kurma ajwa. Kandungan vitamin pada kurma ajwa juga dapat mengatur kualitas pembentukkan jumlah sperma. Mengkonsumsi Kurma Ajwa (Phoenix dactylifera l) dapat mengatur jumlah sperma dan dapat meningkatkan hormon terpenting pada sperma yaitu hormon testosteron dan hormon dehydroepiandrosteron.
Relationship Between Knowledge Level And Attitude With Early Detection Behavior Of Cervical Cancer At Ibnu Sina Hospital Makassar
Authors: Aqmarina Siti Arafiah , Latief Shofiyah , Rahmawati  , Visi Kartika Andy , Zulfahmidah
Published: March 2024

Kanker adalah penyakit keganasan yang menyerang pada dinding leher rahim akibat infeksi humanpapilloma virus. Cara penyebaran ditularkan melalui kontak seksual. Kanker serviks kedua terbanyak menyerang wanita, saat melakukan skrining hasilnya menunjukkan mereka memasuki stadium III B ke atas tingginya angka kasus kanker serviks diakibatkan karena sedikitnya wanita yang mau melakukan skrining terhadap kanker serviks. Metode IVA merupakan salah satu pemeriksaan awal kanker serviks selain itu dapat dilakukan juga metode paps smear. Pengkajian ini deteksi dini kanker serviks di Rumah Sakit Pendidikan Ibnu Sina Makassar. Dengan menggunakan metode penelitian Survey analitik desain cross sectional. Penelitian ini terdapat 64 sampel, 32 terdiagnosis kanker serviks dan 32 yang tidak terdiagnosis kanker serviks. Distribusi data hubungan tingkat pengetahuan dengan perilaku deteksi dini kanker serviks, responden yang terdiagnosis kanker serviks dengan tingkat pengetahuan baik (73,3%), cukup (26,7%), kurang (0%), adapun responden yang tidak terdiagnosis kanker serviks dengan tingkat pengetahuan baik (26,3%), cukup (73,3%), kurang (100%) dengan P-Value 0,000. Hubungan sikap dengan perilaku deteksi dini kanker serviks pada responden yang terdiagnosis kanker serviks dengan sikap baik (53,2%), cukup (45,5%), kurang (33,3%) adapun responden yang tidak terdiagnosis kanker serviks dengan sikap baik (46,8%), cukup (54,3%), kurang (66,7%) dengan P-Value 0,715. kaitan antar taraf pengetahuan pada deteksi dini kanker serviks di Rumah Sakit Pendidikan Ibnu Sina bertarget guna mengamati kaitan melalui tingkat pengetahuan masyarakat dan sikap dengan perilaku makassar hasil menunjukkan bahwa adanya hubungan sedangkan hasil menunjukkan jika tak ada kaitan antar sikap pada perilaku deteksi dini kanker serviks di Rumah Sakit pendidikan Ibnu Sina Makassar
Enhancing maritime safety: A comprehensive review of challenges and opportunities in the domestic ferry sector
Authors: Baig Mirza Zeeshan , Lagdami Khanssa , Mejia Jr. Maximo Q.
Published: March 2024

The domestic ferry sector is uniquely distinctive owing to its challenging navigation conditions and vulnerable accident records that have evoked endless calls for improving maritime safety. The recent adoption of IMO model safety regulations offers viable options for the Member States to standardize incorporation into national law. The operations of domestic ferries range from very large vessels with freight to small craft, which are often the only transport means for a large population of commuters in the developing world. The flexibility of domestic ferries is appealing; on the other hand, their operations are a challenge to handle, raising the need to identify those challenges that are incompatible with smooth operations and business opportunities. The maritime industry, specifically regarding domestic ferry operations, confronts multilayered challenges with direct implications on accident prevention and operational safety that necessitate a thorough analysis for a comprehensive understanding. This study explores five categories, namely, operations, technology and innovations, the human element, policy and regulation, and economics, recognized as pivotal to improving maritime safety. Our content analysis identifies the comprehensive taxonomies, that explain the current challenges and practical opportunities faced by the sector and which are notably lacking, urging efficient tenacity to ensure sustainable domestic ferry operations. The primary objective was to enhance safety standards, promoting sustainable shipping for all stakeholders involved. This study has identified 28 challenges and 90 opportunities, providing a significant pathway for sustainable decision-making that also adds value to the safety of the stakeholders. This study is expected to explore novel and fertile future research areas to promote scholarly discussion in the domestic ferry sector.
Highlights

Policy deficiency - Recognition of inadequate policy frameworks for domestic ferry operations in developing nations, necessitating immediate alignment with international safety standards
Governance strengthening - There is an swift need for strong governance structures to address deficiencies in policy formulation, regulatory enforcement, and operational practices, ensuring effective safety oversight
Standardization challenges - The absence of standardized definitions and categorizations hampers the development of uniform safety regulations within the domestic ferry sector
Capacity building - Continuous training programs are necessary to foster a safety-conscious culture among the domestic ferry workforce
Policy adaptation - Policies must adapt to technological advancements, and collaboration with international bodies is vital for enhancing safety standards within the domestic ferry sector
A. V. Sokolov – classic of the branch science history and philosophy
Authors: Lopatina N. V.
Published: March 2024

The author analyzes the scientific legacy of Arkady Sokolov, an outstanding Russian information scientist, bibliographer, and philosopher. She follows the evolution of scholar’s theoretical concepts in the context of history and philosophy of library and information sciences. The article is based on the analysis of Sokolov’s key works, i. e. the textbook «The introduction into social communication theory”, professional conceptual publication “The philosophy of information”, his theses, and program articles. The author discusses A. V. Sokolov’s contribution into building of the methodological tradition in the library and information sciences. She focuses, in particular, on her own realization of the information approach and its transfer into the research field of library and information sciences. The author explores A. Sokolov’s philosophical concepts and their significance for solving the current problems in the field: development of human resources, defining the status and positioning of library, bibliography and bibliology sciences within the modern system of sciences. The author also expands on her personal memories of Arkady Sokolov.
MICROBIOTA AMBIENTAL DEL DEPARTAMENTO DE NEONATOLOGIA EN EL INSTITUTO NACIONAL MATERNO PERINATAL, LIMA, PERÚ
Authors: Dávila-Aliaga Carmen Rosa , Mendoza Ibañez Elina , Torres Marcos Elsa , Soza Bieli-Bianchi Maria Gabriela , Arango Ochante Pedro , Ramos Chirinos María del Carmen , Cabanillas Choque Jannett Consuelo , Vallas Castillo Jamie Ysabel , Del Castillo Bao Stephanie Brigitte , Grimaldo D´Ambrosio Guiovanni Guiselle
Published: March 2024

Introduction. Healthcare-associated infections (IAAS) increase neonatal morbidity and mortality. Identifying the microbiological profile and sensitivity of the microbiota allows us to reduce infection rates, rationalize the use of antibiotics and improve neonatal survival. Objectives. To know the environmental microbiota and antimicrobial sensitivity in the Department of Neonatology (DN). Methods. Observational, descriptive, cross-sectional study, carried out between April and May 2021, in the Intensive Care, Intermediate and Immediate Care services of the DN of the Instituto Nacional Materno Perinatal, a reference center for maternal and neonatal care. 144 surfaces were selected from the hospitalized patient environment. Using swabbing technique, samples were obtained and then seeded in common and selective culture media. Sensitivity was determined using Kirby-Bauer diffusion disks, the analysis of variables was performed with SPSS version 22.0 Results. Of 147 samples, 67% gave positive cultures with pathogenic bacteria. In immediate care 50% tested positive, in intermediate care 46.5% and in NICU 39.7%. The 100% contaminated surfaces were fan screens, electroencephalogram monitor, chart holders and scales. Of 41 hands of health personnel, 29.3% were contaminated: 54.5% nursing technicians, 30% doctors and 23% nursing graduates. The isolated germs were SCN (67%) sensitive to vancomycin, Enterococcus (16.5%) sensitive to ampicillin and vancomycin, Pseudomonas (8.2%) to meropenem, Escherichia coli (2.4%) to gentamicin and amikacin, Klebsiella (1.2%). Conclusion. Pathogens causing IAAS were isolated on surfaces in the environment of our patients. The bacterial agents found have high antimicrobial resistance and virulence.
Roma Devri Küçük Asyası'nda Sporcu Dernekleri: Pisidia Antiokheia Örneği
Authors: ALTIN Recep
Published: March 2024

Tüm kurumlar gibi antik dönemin sanatçı ve sporcu dernekleri de bir dizi temel ihtiyacın neticesi olarak ortaya çıkıp gelişmiştir. Başlangıçta sınırlı bir coğrafyada -Hellas anakarasında- düzenlenen agonistik festivallere (bedensel, atlı ve müzikal yarışmalar) yalnızca yakın kent ve bölgelerden katılımcılar iştirak ediyordu. Günümüz küreselleşme sürecini andıran Hellenistik Dönem’le birlikte ise agonistik festivaller Akdeniz dünyasının dört bir köşesine yayılmıştır. Yaşanan bu hızlı değişim, herkesten daha çok agonistik organizasyonların baş aktörleri olan sanatçı ve sporcuları etkilemiştir. Roma’nın MÖ II. yüzyılda Akdeniz’in doğusunda askeri ve siyasi bir figür olarak ortaya çıkıp MÖ I. yüzyıl itibariyle bölgede tek hâkim güç olmasıyla var olan tüm festivaller tek çatı altında birbirine bağlanmıştır. Böylelikle geniş bir coğrafyada muazzam bir festival ağı kurulmuştur. Nitelikli bilgi ihtiyacının had safhaya çıktığı bu noktada ya da ortamda sporcu derneklerinin ilk kez Küçük Asya’da ortaya çıktığı görülmektedir. Sporcu dernekleri üzerine günümüze değin birçok çalışma yapılmış olmasına rağmen, konu ilk günkü muğlaklığını ve tartışılırlığını halen korumaktadır. Özellikle derneklerin ortaya çıkış süreci, şekli ve de yerleşik yerel şubeler problemi tartışmaların odak noktasını oluşturmaktadır. Üç bölümden oluşan bu çalışma kapsamında kısaca Yunan-Roma dünyasındaki festival geleneğine değinildikten sonra sporcu derneklerinin ortaya çıkış süreci, tarihi seyri, yapısı, işlevleri, merkezi otoriteyle ilişkisi ve Pisidia Antiokheia’sı özelinde yerleşik yerel şubeler sorunu incelenecektir.
Pengenalan Identitas Budaya Nusantara Lewat Buku Mewarnai “The Time Machine Coloring Book Bernostalgia dengan Warna”
Authors: Kusumohendrarto Raden Hadapiningrani , Fitri Nofria Doni , Sani Muhammad Nur
Published: March 2024

Dalam kehidupan sehari-hari, seseorang akan mengalami pasang surut secara psikologis, baik secara fisik maupun spiritual. Hal tersebut dapat menyebabkan seseorang mengalami kelelahan, kebosanan, dan stres. Menyikapi hal tersebut, banyak cara yang bisa dilakukan, salah satunya dengan mewarnai buku ilustrasi. Buku ilustrasi mewarnai berjudul “The Time Machine Coloring Book BERNOSTALGIA dengan WARNA” yang disajikan dalam buku ini memiliki hal yang menarik karena memuat identitas budaya nusantara Indonesia yang beragam, mulai dari aktivitas sehari-hari hingga objek dan sebagainya. Serta Ilustrasi dapat sekaligus memberikan pesan edukasi secara tidak langsung melalui visual yang menarik. Penelitian ini akan menggunakan analisis kualitatif deskriptif dengan menganalisis ilustrasi, teks, dan tema dalam buku. Peran ilustrasi buku mewarnai ini diharapkan dapat menjadi media atraksi, minat, edukasi, dan terapi warna yang memperkenalkan identitas budaya nusantara khususnya budaya tradisionalnya.
Editorial
Authors: Cadernos do Tempo Presente Editores
Published: March 2024

A Cadernos do Tempo Presente chega sua segunda edição do ano de 2023. Nela, contamos com artigos e resenhas que nos apresentam pesquisas na área de História do Tempo Presente. Esta edição também marca a mudança da identidade visual da revista com a adoção de uma novo logo e de um novo modelo de diagramação.
No primeiro artigo, por meio de um estudo baseado na análise de documentos e da literatura produzida por organizações governamentais ou não, bem como por entrevistas com especialista sobre o tema, Karl Schurster e Luzilete Falavinha Ramos nos apresentam reflexões sobre a história do ensino do holocausto transcorrendo por suas origens, temas e métodos. A seguir, Dilton Candido Santos Maynard e Diego Leonardo Santana Silva nos mostram como a Guerra Fria foi representada no universo de Batman com um estudo sobre o clássico quadrinho O Cavaleiro das Trevas, de Frank Miller.
No terceiro artigo da edição, Luís Fellipe F. Afonso expõe um estudo sobre o rock e a censura na década de 1980. O texto demonstra como o regime utilizada a censura para cercear pensamentos críticos, sendo o BRock um dos gêneros musicais mais censurados da época visando reprimir os artistas em prol de ideias favoráveis à ditadura. A seguir Felipe Cazetta traz uma análise da atuação de Jacques Ploncard D’Assac, um mediador entre os salazaristas e os estrangeiros, entre eles os franquistas, durante o regime de Salazar em Portugal no período após a Segunda Guerra Mundial.
Já Lucas Alves da Silva traz um estudo sobre a preocupação dos militares brasileiros durante a abertura política e os receios por parte de atores do regime com uma eventual punição por crimes cometidos contra os Direitos Humanos. Silva reflete sobre o posicionamento dos militares e políticos em relação ao tema por meio da análise de publicações nos jornais Diário do Paraná e Correio de Notícias. E, em no último artigo, temos Júlia Amaral Amato Moreira trabalhando com memórias de filhos de sobreviventes do Holocausto em relatos orais, entendidos sob a ótica da Pós-memória extraídos de filhos de sobreviventes do Holocausto em Belo Horizonte.
Por fim, completamos nossa edição com a resenha do livro Governança e Sustentabilidade de Renato Cader e Teresa Villac escrita por Maralysa Correia de Souza Cavalcanti.
Agradecemos aos nossos parceiros, leitores e colaboradores e desejamos uma ótima leitura.
 
 
Atenciosamente,
Os editores.
PAKAIAN MUSLIMAH DALAM PERSPEKTIF HADIS DAN HUKUM ISLAM
Authors: Maidatus Sa'diyah  , Muhammad Abror Rosyidin
Published: March 2024

Terlepas apakah mereka mengikuti aturan-aturan Islam atau aturan-aturan masyarakat umum, orang-orang yang berpikiran kuat dan berakal sehat berkeinginan untuk tampil menarik. Masyarakat Indonesia dengan mayoritas penduduk yang agamanya Islam harus mengetahui cara berpakaian yang pantas sesuai dengan keyakinan mereka. Namun baru-baru ini banyak perempuan Muslim yang ditemukan tidak berpakaian sesuai dengan hukum dan ajaran Islam. Perempuan Muslim yang terbiasa mengikuti norma-norma berpakaian Islam yang sudah mendarah daging dalam masyarakat dan terbiasa berpakaian sesuai hukum syariah perlu diajari praktik-praktik berbusana yang baik sejak usia muda. Tujuan utama artikel ini adalah untuk mengedukasi pembaca mengenai sopannya berpakaian muslimah yang sesuai dengan syariat agama islam. Kajian ini menunjukkan bahwa, secara ringkas, dengan menggunakan sudut pandang hadis Nabi.
KOMPRES AIR HANGAT EFEKTIF TERHADAP PENURUNAN SUHU TUBUH DI DAERAH AXILLA PADA ANAK DENGAN DEMAM TYPHOID
Authors: Fhirawati Fhirawati , Mulyana A. Saputri , Karim Hamdayani - , Darise Meilany -
Published: March 2024

Tujuan: Untuk mengetahui perbandingan efektifitas pemberian kompres air hangat pada daerah lipatan paha dan axilla terhadap penurunan suhu tubuh pada anak dengan demam typhoid di RS Bhayangkara Makassar. Metode Penelitian: Jenis penelitian penelitian experimental dengan pendekatan quasi experimental (penelitian eksperimen semu) melalui rancangan penelitian two group pre-post test design, dokumentasi dan observasi. Hasil: perbandingan derajat suhu tubuh antara kelompok kompres air hangat pada daerah lipatan paha dan kelompok kompres air hangat pada daerah axilla diperoleh hasil uji t yaitu -18.007 dan pada daerah axilla yaitu -22.402. Dengan hasil uji menunjukkan bahwa pemberian kompres air hangat terhadap penurunan suhu tubuh dengan nilai thitung masing-masing pada daerah lipatan paha -18.007, daerah axilla -22.402 dimana ttabel 2,375. Dengan nilai ρ 0,000 < α 0,01. Implikasi penelitian untuk menurunkan suhu badan dengan penggunaan kompres daerah axilla sebagai alternatif dalam kompres selain pemberian kompres daerah lipatan paha diperlukan adanya penyebaran informasi tentang pengaruh pemberian kompres air hangat pada daerah lipatan paha dengan axilla. Rekomendasi: perlu adanya konsep community system berbasis masyarakat dalam melakukan pendekatan dan peningkatan pelayanan kesehatan kepada masyarakat melalui Pemberian informasi di rumah sakit dan orang tua pasien khususnya di rumah sakit bhayangkara Makassar.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN MUTU PELAYANAN RUMAH SAKIT TERHADAP KEPUASAN PASIEN DI RUANG RAWAT INAP RSKD IBU DAN ANAK PERTIWI MAKASSAR
Authors: Liliskarlina Liliskarlina , Faisal Faisal , AR. Andi Kayani
Published: March 2024

Mutu pelayanan rumah sakit menjadi salah satu faktor penting untuk menciptakan kepuasan pasien. Pelayanan yang berkualitas dalam konteks pelayanan di rumah sakit adalah memberikan pelayanan kepada pasien dan keluarganya sesuai dengan standar kualitas.Penelitian ini bertujuan untuk mengetahui hubungan mutu pelayanan rumah sakit berdasarkan faktor dimensi kompetensi teknis, akses terhadap pelayanan, kenyamanan, hubungan antar manusia, dan ketepatan waktu terhadap kepuasan pasien di ruang rawat inap RSKD Ibu dan Anak Pertiwi Makassar. Jenis penelitian ini adalah penelitian kuantitatif dengan menggunakan desain cross sectional study. Pengambilan sampel menggunakan accidental sampling, diperoleh sampel sebanyak 175 responden.  Analisis data menggunakan uji chi-square  dengan α= 0,05.Berdasarkan hasil penelitian menunjukkan bahwa ada hubungan antara dimensi kompetensi teknis (p= 0,001), akses terhadap pelayanan (p= 0,001), hubungan antar manusia (p= 0,003), dan ketepatan waktu (p= 0,036) terhadap kepuasan pasien di ruang rawat inap Rumah Sakit Khusus Daerah Ibu dan Anak Pertiwi Makassar, dan tidak ada hubungan antara dimensi kenyamanan (p= 0,185) terhadap kepuasan pasien di ruang rawat inap Rumah Sakit Khusus Daerah Ibu dan anak Pertiwi Makassar.Disarankan kepada Rumah Sakit Khusus Daerah Ibu dan Anak Pertiwi Makassar memperhatikan pengunjung yang membawa anak usia dibawah 12 tahun sehingga tidak mengganggu kenyamanan pasien maupun pengunjung lain.
Exosomes derived from MSC as drug system in osteoarthritis therapy
Authors: Wen Shuzhan , Huang Xin , Ma Jingchun , Zhao Guanglei , Ma Tiancong , Chen Kangming , Huang Gangyong , Chen Jie , Shi Jingsheng , Wang Siqun
Published: March 2024

Osteoarthritis (OA) is the most common degenerative disease of the joint with irreversible cartilage damage as the main pathological feature. With the development of regenerative medicine, mesenchymal stem cells (MSCs) have been found to have strong therapeutic potential. However, intraarticular MSCs injection therapy is limited by economic costs and ethics. Exosomes derived from MSC (MSC-Exos), as the important intercellular communication mode of MSCs, contain nucleic acid, proteins, lipids, microRNAs, and other biologically active substances. With excellent editability and specificity, MSC-Exos function as a targeted delivery system for OA treatment, modulating immunity, inhibiting apoptosis, and promoting regeneration. This article reviews the mechanism of action of MSC-Exos in the treatment of osteoarthritis, the current research status of the preparation of MSC-Exos and its application of drug delivery in OA therapy.
Clinical distribution of carbapenem genotypes and resistance to ceftazidime-avibactam in Enterobacteriaceae bacteria
Authors: Zhu Xueyun , Guo Caixia , Xu Shengxi , Lv Fei , Guo Zhusheng , Lin Sisi , Yang CongZhu , Deng Zhuliang , Chen Shaofeng , Huang Ya , Zhao Zuguo , Li Lu
Published: March 2024

Introduction

Bacterial resistance is a major threat to public health worldwide. To gain an understanding of the clinical infection distribution, drug resistance information, and genotype of CRE in Dongguan, China, as well as the resistance of relevant genotypes to CAZ-AVI, this research aims to improve drug resistance monitoring information in Dongguan and provide a reliable basis for the clinical control and treatment of CRE infection.

Methods

VITEK-2 Compact automatic analyzer was utilized to identify 516 strains of CRE collected from January 2017 to June 2023. To determine drug sensitivity, the K-B method, E-test, and MIC methods were used. From June 2022 to June 2023, 80 CRE strains were selected, and GeneXpert Carba-R was used to detect and identify the genotype of the carbapenemase present in the collected CRE strains. An in-depth analysis was conducted on the CAZ-AVI in vitro drug sensitivity activity of various genotypes of CRE, and the results were statistically evaluated using SPSS 23.0 and WHONET 5.6 software.

Results

This study identified 516 CRE strains, with the majority (70.16%) being K.pneumoniae, followed by E.coli (18.99%). Respiratory specimens had highest detection rate with 53.77% identified, whereas urine specimens had the second highest detection rate with 17.99%. From June 2022 to June 2023, 95% of the strains tested using the CRE GeneXpert Carba-R assay possessed carbapenemase genes, of which 32.5% were blaNDM strains and 61.25% blaKPC strains. The results showed that CRE strains containing blaKPC had a significantly higher rate of resistance to amikacin, cefepime, and aztreonam than those harboring blaNDM.

Conclusions

The CRE strains isolated from Dongguan region demonstrated a high resistance rate to various antibiotics used in clinical practice but a low resistance rate to tigecycline. These strains produce Class A serine carbapenemases and Class B metals β-lactamases, with the majority of them carrying blaNDM and blaKPC. Notably, CRE strains with blaKPC and blaNDM had significantly lower resistance rates to tigecycline. CAZ-AVI showed a good sensitivity rate with no resistance to CRE strains carrying blaKPC. Therefore, CAZ-AVI and tigecycline should be used as a guide for rational use of antibiotics in clinical practice to effectively treat CRE.
Helicobacter pylori glycan biosynthesis modulates host immune cell recognition and response
Authors: Barrett Katharine A. , Kassama Francis Jacob , Surks William , Mulholland Andrew J. , Moulton Karen D. , Dube Danielle H.
Published: March 2024

Introduction

The pathogenic bacterium Helicobacter pylori has evolved glycan-mediated mechanisms to evade host immune defenses. This study tests the hypothesis that genetic disruption of H. pylori glycan biosynthesis alters immune recognition and response by human gastric epithelial cells and monocyte-derived dendritic cells.

Methods

To test this hypothesis, human cell lines were challenged with wildtype H. pylori alongside an array of H. pylori glycosylation mutants. The relative levels of immune response were measured via immature dendritic cell maturation and cytokine secretion.

Results

Our findings indicate that disruption of lipopolysaccharide biosynthesis diminishes gastric cytokine production, without disrupting dendritic cell recognition and activation. In contrast, variable immune responses were observed in protein glycosylation mutants which prompted us to test the hypothesis that phase variation plays a role in regulating bacterial cell surface glycosylation and subsequent immune recognition. Lewis antigen presentation does not correlate with extent of immune response, while the extent of lipopolysaccharide O-antigen elaboration does.

Discussion

The outcomes of this study demonstrate that H. pylori glycans modulate the host immune response. This work provides a foundation to pursue immune-based tailoring of bacterial glycans towards modulating immunogenicity of microbial pathogens.
A long-term cohort study: the immune evasion and decreasing neutralization dominated the SARS-CoV-2 breakthrough infection
Authors: Liu Qianyun , Jin Meihua , Mei Fanghua , Fan Hui , Gu Mengxue , Zhang Yuzhen , Qian Shengnan , Tan Xue , Ji Lei , Zhang Zhen , Chen Guozhong , Yan Huan , Chen Yu , Lan Ke , Geng Qing , Cai Kun , Zhou Li
Published: March 2024

Most of vaccinees and COVID-19 convalescents can build effective anti-SARS-CoV-2 humoral immunity, which helps preventing infection and alleviating symptoms. However, breakthrough viral infections caused by emerging SARS-CoV-2 variants, especially Omicron subvariants, still pose a serious threat to global health. By monitoring the viral infections and the sera neutralization ability of a long-tracked cohort, we found out that the immune evasion of emerging Omicron subvariants and the decreasing neutralization led to the mini-wave of SARS-CoV-2 breakthrough infections. Meanwhile, no significant difference had been found in the infectivity of tested SARS-CoV-2 variants, even though the affinity between human angiotensin-converting enzyme 2 (hACE2) and receptor-binding domain (RBDs) of tested variants showed an increasing trend. Notably, the immune imprinting of inactivated COVID-19 vaccine can be relieved by infections of BA.5.2 and XBB.1.5 variants sequentially. Our data reveal the rising reinfection risk of immune evasion variants like Omicron JN.1 in China, suggesting the importance of booster with updated vaccines.
Machine learning analysis of patients’ perceptions towards generic medication in Greece: a survey-based study
Authors: Kassandros Konstantinos , Saranti Evridiki , Misailidou Evropi , Tsiggou Theodora-Aiketerini , Sissiou Eleftheria , Kolios George , Constantinides Theodoros , Kontogiorgis Christos
Published: March 2024

Introduction:

This survey-based study investigates Greek patients’ perceptions and attitudes towards generic drugs, aiming to identify factors influencing the acceptance and market penetration of generics in Greece. Despite the acknowledged cost-saving potential of generic medication, skepticism among patients remains a barrier to their widespread adoption.

Methods:

Between February 2017 and June 2021, a mixed-methods approach was employed, combining descriptive statistics with advanced machine learning models (Logistic Regression, Support Vector Machine, Random Forest, Gradient Boosting, and XGBoost) to analyze responses from 2,617 adult participants. The study focused on optimizing these models through extensive hyperparameter tuning to predict patient willingness to switch to a generic medication.

Results:

The analysis revealed healthcare providers as the primary information source about generics for patients. Significant differences in perceptions were observed across demographic groups, with machine learning models successfully identifying key predictors for the acceptance of generic drugs, including patient knowledge and healthcare professional influence. The Random Forest model demonstrated the highest accuracy and was selected as the most suitable for this dataset.

Discussion:

The findings underscore the critical role of informed healthcare providers in influencing patient attitudes towards generics. Despite the study’s focus on Greece, the insights have broader implications for enhancing generic drug acceptance globally. Limitations include reliance on convenience sampling and self-reported data, suggesting caution in generalizing results.
Analytical solution of the stress field and plastic zone at the tip of a closed crack
Authors: Wu Guanzhong , Wang Wensong , Peng Shaochi
Published: March 2024

The investigation of stress field and plastic zone distribution at the closed crack tip provides a fundamental basis for failure analysis and life prediction of geotechnical materials. Closed crack is a common crack in geotechnical materials. Studying the distribution of stress field and plastic zone at the tip of closed crack can provide theoretical basis for stability evaluation of geotechnical structures. In this study, we employ the superposition principle to obtain complex function solutions for the stress field and displacement field at the crack tip. Furthermore, we analyze the plastic zone distribution at the crack tip based on the Mohr Coulombs criterion. We investigate how factors such as crack angle, confining pressure, and material properties influence the stress field, displacement field, plastic zone size, and crack propagation direction. Our results demonstrate that this method effectively characterizes the distribution of stress field and displacement field at closed crack tips. Moreover, we elucidate that wing cracks are primarily formed due to tension-shear coupling effects. The solutions for the stress field and displacement field at the crack tip are obtained using the superposition principle. The distribution of the plastic zone at the crack tip is analyzed based on the M-C (Mohr-Coulomb) criterion. Subsequently, an analysis is conducted to investigate the influence of crack angle, confining pressure, and material properties on stress field, displacement field, plastic zone, and crack propagation direction. Lower crack angles and higher confining pressures effectively suppress slip between crack surfaces by reducing tension-shear coupling effects and inhibiting wing foil crack development. The results further indicate that the rock cohesion and internal friction angle exert negligible influence on the stress field, displacement field, plastic zone shape at the crack tip, as well as the growth direction of new cracks. The results demonstrate the effective representation of stress field and displacement field at the closed crack tip using this method. The stress distribution at the crack tip reveals that the tension-shear coupling effect primarily contributes to wing crack formation. Lower crack angles and higher confining pressures effectively suppress surface slip, reduce tension-shear coupling effects, and inhibit wing crack propagation. Furthermore, material properties do not influence the crack propagation angle, stress field, or displacement field.
Improvement in simultaneous processing through metacognitive instruction
Authors: Ares Ferreirós Martina , Alfonso Gil Sonia , Rodríguez Enríquez Mónica , Conde Rodríguez Ángeles , Deaño Deaño Manuel
Published: March 2024

This study presents the improvement generated in simultaneous processing by the application of metacognitive instruction to 3rd grade primary education students. A pre-post-follow-up test design was used. The sample consisted of 30 students from one classroom. Two groups were formed; an intervention group comprising students in the classroom who presented difficulties in simultaneous processing, showing a cognitive weakness that compromises reading comprehension, and a comparison group comprising the rest of the students in the class. The instruments used were the Das-Naglieri Cognitive Assessment System (DN CAS), Assessment of Reading Comprehension (ACL) test and the Reading Awareness Scale (ESCOLA). The groups were equivalent in socioeconomic and cultural status and in successive processing. Reading and study variables were used as differentiators: simultaneous processing and reading awareness. A metacognitive training program based on the Planning Facilitation method was applied to the intervention group. The comparison group followed the usual curricular activities of the classroom and for the education level, according to the traditional teaching model. The program was implemented in 48 sessions over 12 weeks. After the intervention, the group with weakness improved significantly in simultaneous processing and reading awareness; the comparison group did not show any change in their initial scores. The metacognitive instruction that facilitates discussion between students and reflective verbalization about reading tasks promotes improvement in reading awareness and in the simultaneous processing necessary for reading comprehension.
Investigating the influence of yarn characteristics on microfibre release from knitted fabrics during laundering
Authors: Hazlehurst Alice , Sumner Mark , Taylor Mark
Published: March 2024

Microfibres generated and released during the use and laundering of textiles have been identified as an important source of environmental pollution. The quantity of microfibres released from a fabric can be influenced by several external factors, such as laundering conditions and consumer use, as well as intrinsic factors such as the fibre composition, yarn characteristics, and fabric structure. This study investigates the influence of various yarn characteristics on microfibre release from knitted fabrics as well as exploring the generation of microfibres during the knitting process. Fibre composition and the yarn spinning system has the greatest influence on microfibre release. The greatest quantity of microfibre was released from ring-spun lyocell (1313 ± 140 mg/kg) and the lowest quantity was released from vortex-spun polyester (80 ± 26 mg/kg). The yarn spinning system was also found to have a significant influence, with vortex-spun yarns consistently demonstrating lower microfibre release than corresponding ring-spun yarns, likely due to the reduced hairiness of yarns spun by the vortex system. The importance of fibre damage during the knitting process was also investigated. Several yarns demonstrated significantly greater microfibre release in knitted form compared to loose, hank form, but the scale of difference was found to be dependent on fibre composition.
Urban noise slows down the antipredator reaction of Eurasian Magpies
Authors: Abou-Zeid Farah , Benedetti Yanina , Siretckaia Anastasiia , Morelli Federico
Published: March 2024

Urban areas are known to have high levels of noise pollution, which can impact an animal’s antipredator behavior. Noise can either distract the animal or mask the sounds of a predator, increasing the animal’s vulnerability to predation. However, the prey may increase vigilance in noisier environments, thus reducing energy and time spent on other activities. Alert Distance (AD) refers to the distance at which an animal becomes alert to a potential predator approaching. Flight Initiation Distance (FID) is the distance from the potential predator at which the animal flees. We studied the impact of ambient noise pollution on the AD and a corrected FID (FID/AD) of Eurasian Magpies (Pica pica) using a field investigator as a potential predator walking towards birds at a constant speed. We found that the noise level did not affect the AD. Still, noise had a negative effect on the Eurasian Magpies’ FID/ADs, suggesting that noise may slow their reaction to a potential threat but not their ability to detect it. Thus, our research highlights that urban noise pollution can increase an individual's vulnerability to predation, even when predators are still detectable. Ambient noise may distract the bird by diverting some of its limited attention and causing a delayed response to the predators. Alternatively, noise could be masking auditory cues that would have otherwise been added together with visual cues to cause an enhanced response. More research is necessary to understand the effects of noise pollution on the antipredator behavior of birds in urban areas, taking into account the specific strategies and adaptations of each species.
The antibodies 3D12 and 4D12 recognise distinct epitopes and conformations of HLA-E
Authors: Brackenridge Simon , John Nessy , Früh Klaus , Borrow Persephone , McMichael Andrew J.
Published: March 2024

The commonly used antibodies 3D12 and 4D12 recognise the human leukocyte antigen E (HLA-E) protein. These antibodies bind distinct epitopes on HLA-E and differ in their ability to bind alleles of the major histocompatibility complex E (MHC-E) proteins of rhesus and cynomolgus macaques. We confirmed that neither antibody cross-reacts with classical HLA alleles, and used hybrids of different MHC-E alleles to map the regions that are critical for their binding. 3D12 recognises a region on the alpha 3 domain, with its specificity for HLA-E resulting from the amino acids present at three key positions (219, 223 and 224) that are unique to HLA-E, while 4D12 binds to the start of the alpha 2 domain, adjacent to the C terminus of the presented peptide. 3D12 staining is increased by incubation of cells at 27°C, and by addition of the canonical signal sequence peptide presented by HLA-E peptide (VL9, VMAPRTLVL). This suggests that 3D12 may bind peptide-free forms of HLA-E, which would be expected to accumulate at the cell surface when cells are incubated at lower temperatures, as well as HLA-E with peptide. Therefore, additional studies are required to determine exactly what forms of HLA-E can be recognised by 3D12. In contrast, while staining with 4D12 was also increased when cells were incubated at 27°C, it was decreased when the VL9 peptide was added. We conclude that 4D12 preferentially binds to peptide-free HLA-E, and, although not suitable for measuring the total cell surface levels of MHC-E, may putatively identify peptide-receptive forms.