bluuebunny/crossref_metadata_2025 huggingface dataset:
Some Geometric Properties of Close- to- Convex Functions
Authors: Alhily Shatha S.
Published: October 2024

The objective of this paper is to present some geometric properties of the close to convex function  f when f is an analytic, univalent self-conformal mapping defined in the open unit disk D={z∈C: |z|<1},  and on the boundary of D. One of the goals of this work was determining the sharp bound for the function of form  f(z)=z/(1-z)^2δ   , 0<δ<1, when R(f^'/g^' (w_1))≥-2+δ/w_1   , for a some w_1∈∂D And  another, if f has angular limit at  p∈∂D . Then the inequality |(f^' (z))/(g^' (z) )|≥(-(1-2δ))/2(1+ δ)    is sharp with extremal functions  f(z)=z/(1-z)^2δ   , and   g(z)=z/(1+z), where 0<δ<1. Finally, if  f  is extended continuously to the boundary of D , then  |  (f^'/g^' )(p)|≥  |1-2δ|(|1-2δ|-2)/|p-δ |   ; 0<δ<1.
Spectrophotometric determination of Salicylamide one of the novel COVID -19 protocols via new design Flow Injection with Merging-Zone Technique
Authors: Al-Badri Shurooq Badri , Muhamad Yasmeen H.
Published: October 2024

Recently, attention has turned to drugs like salicylamide for treating COVID-19. Several studies have reported simple, fast, and sensitive methods for measuring salicylamide levels. However, potential limitations remain regarding interference from other drugs and accuracy of results. To tackle this issue, researchers combined the standard addition technique with flow injection analysis. As part of this investigation, the reaction involving Fe (III), salicylamide, and 1,10-phenanthroline at a temperature of 55°C was examined using a spectrophotometer set at a wavelength of 528 nm. Thus, the new design was able to show an excellent linearity over the concentration range of (2-30 μg/mL) and (25-300 μg/mL), with correlation coefficients ( ) of 0.9669 and 0.9781, respectively. In addition, physical and chemical variables were optimized to obtain the best results. There was a significant positive correlation between the new design and  NIR micro-spectrometers device (handheld) outcomes.
Praktik Dagang di Pakan Serikat Koto VII Basambilan Koto, Sijunjung (1980-1998)
Authors: Irawanti Pungki
Published: October 2024

Abstract: This research aims to analyze how traditional markets shape local capitalist practices in Pakan Serikat Koto VII Basambilan Koto, Sijunjung, from 1980 to 1998. The research employs a historical method with four stages: heuristics, criticism, interpretation, and historiography. The research findings demonstrate that traditional markets have shaped local capitalist practices in Pakan Serikat Koto VII Basambilan Koto. These practices manifest in various forms, including trading systems, social relations, cultural exchange, and social change. The establishment of Pakan Serikat VII Koto has driven social change in the community, such as changes in livelihood systems and lifestyles. The research concludes that traditional markets play a crucial role in shaping local capitalist practices in Pakan Serikat Koto VII Basambilan Koto. Traditional markets serve not only as places for exchanging goods and services but also as venues for social interaction, cultural exchange, and social change.
Keywords: Traditional market, Local capitalism, Pakan Serikat Koto VII Basambilan Koto, Sijunjung, 1980-1998
The Resurgence of New Malay Nationalism on social media post-GE14
Authors: Mohamed Salleh Shahnon , Sualman Ismail
Published: October 2024

The 14th General Election has significantly changed Malaysia when Barisan Nasional suffered its first ever defeat since Independence. However, among the Malay majority, there was a growing sense of political anxiety and uneasiness as a result of the perceived loss of power, and to some extent, the erosion of national identity. In response, the nationalists and the Islamists have regrouped and reunited. This is manifested with the formal alliance of the two largest Malay-based parties, UMNO and PAS. Amidst the backdrop of this new political realignment, social media played an important role in setting the narrative, and mobilising the masses. Therefore, working from within this background, this paper analysed the discourse of the new Malay nationalism on social media by employing a social media tool, SeoTools, to analyse the Twitter data. The findings revealed a new insight into the dynamics of the Malay mind and motivation from the context of politics, religion, and economy. There was a significant correlation between popular sentiment and social media discourse, in that there was a renewed resurgence to reassert traditional values and identity. The failure to rein in the emotion, and the expectation, eventually cause the fall of Pakatan Harapan in 2020.
Wall-Modeled Large-Eddy Simulation Method for Unstructured-Grid Navier–Stokes Solvers
Authors: Wang Li , Anderson William Kyle , Nielsen Eric J. , Iyer Prahladh S. , Diskin Boris
Published: October 2024

This paper reports on the implementation and assessment of a wall-modeled large-eddy simulation (WMLES) methodology in an unstructured-grid, node-centered flow solver, FUN3D, that is developed and supported at the NASA Langley Research Center. Finite-volume (FV) and finite-element (FE) discretization schemes considered in the study provide formal second-order spatial accuracy. Large-eddy simulations (LES) resolve large-scale turbulent-flow features, and small-scale effects are modeled using the Vreman subgrid-scale model. At solid-wall boundaries, a shear-stress model is employed to provide a proper boundary-flux closure. The nonlinear equations are integrated in time using either an optimized backward difference formula or an implicit multistage Runge–Kutta temporal scheme. The implicit equations at each time step are solved by strong nonlinear iteration schemes. WMLES demonstrations are shown for two high-lift configurations, namely, the McDonnell Douglas 30P30N multi-element airfoil and a NASA High-Lift Common Research Model. Results show that the WMLES approaches implemented in the FV and FE discretization methods produce consistent solutions and are capable of capturing key aerodynamic characteristics and flow structures for high-lift configurations at a wide range of angles of attack, including maximum-lift conditions. In the 30P30N example, correct trends in the variations of integrated aerodynamic forces and moments, surface pressure distributions, and boundary-layer profiles are captured as the Reynolds number is increased.
Edukasi Pengembangan Inovasi Berbasis Keuangan Digital Bagi Pelaku Usaha Mikro Kecil Menengah Kabupaten Tangerang
Authors: Goestjahjanti Francisca Sestri , Winanti Winanti , Hasna Shofwatun , Nurasiah Nurasiah , Himmy'azz Istajib Kulla , Suwita Jaka , Kumoro Dwi Ferdiyatmoko Cahya , Basuki Sucipto , Jubaedah Ida
Published: October 2024

Penggunaan keuangan digital bagi sebagian pelaku usaha menjadi hal baru dan kondisi di lapangan masih banyak pelaku usaha yang belum menggunakan keuangan digital. Rasa takut dan waswas akan kehilangan uang dan data, serta belum adanya edukasi secara menyeluruh menjadi faktor utama para pelaku usaha enggan menggunakan uang digital. Tujuan edukasi ini adalah untuk memberikan pemahaman kepada para pelaku usaha untuk penggunaan keuangan digital untuk transaksi setiap harinya. Metode yang digunakan dengan diskusi melalui talk show dimana narasumber menyampaikan materi dengan dipandu oleh seorang moderator dalam pelaksanaan diskusi. Hasil dari kegiatan edukasi ini adalah para peserta dalam hal ini pelaku usaha, mahasiswa, dosen, dan masyarakat umum untuk menggunakan keuangan digital di setiap aktivitas transaksi jual beli. Setelah kegiatan berlangsung dilakukan monitoring dan evaluasi melalui pemberian pertanyaan kepada peserta mengenai beberapa materi sejauh mana peserta memahami materi yang disampaikan oleh narasumber.
Penekanan Angka Stunting Melalui Edukasi Bahaya dan Pencegahan Stunting pada Kader Posyandu di Desa Polokarto, Sukoharjo
Authors: Ariyanti Lilik , Semartini Atur , Saad Muhammad
Published: October 2024

Stunting merupakan masalah gizi yang terjadi pada anak yang menyebabkan anak mengalami kondisi pendek atau sangat pendek menurut usianya. Angka stunting di Indonesia terus ditekan. Salah satu faktor dari stunting adalah kurangnya pengetahuan akan bahaya dan pencegahan stunting. Oleh karenanya, penting adanya peningkatan pengetahuan dan kesadaran masyarakat akan bahaya dan pencegahan stunting guna menekan angka stunting. Kegiatan pengabdian masyarakat ini dilakukan dengan cara penyuluhan atau edukasi yang juga disertai dengan pemberian pretest dan posttest guna mengevaluasi peningkatan pengetahuan akan stunting. Kegiatan pengabdian masyarakat ini menyasar 36 kader posyandu di Desa Polokarto, Sukoharjo. Kegiatan pengabdian masyarakat ini menunjukkan bahwa melalui edukasi terjadi peningkatan pengetahuan masyarakat akan bahaya dan pencegahan stunting. Ada peningkatan 13,46 poin dari sebelum penyuluhan dan setelah penyuluhan. Rerata poin pretest peserta adalah 69,62. Sedangkan rerata poin atau nilai peserta setelah penyuluhan adalah 83,08. Hasil tersebut membuktikan bahwa edukasi bahaya dan pencegahan stunting efektif meningkatkan pengetahuan masyarakat.
Pemanfaatan Ma-Llow (Maternity Pillow) sebagai Upaya Peningkatan Kesehatan Fisik dan Psikis Masa Kehamilan dan Persalinan di Wilayah Puskesmas Rowosari
Authors: Munafiah Durrotun , Maftuchah Maftuchah , Ulya Fitria Hikmatul , Suhud Hargokendar , Sari Novita
Published: October 2024

Kehamilan dan persalinan merupakan suatu periode yang special bagi wanita dan keluarganya. Periode ini dapat menghadirkan berbagai macam emosi pada wanita, alah satunya adalah kecemasan. Kecemasan dan rasa takut yang dialami oleh ibu bersalin sangat bervariasi. Kondisi ini dapat terjadi sebagai akibat dari perubahan-perubahan yang terjadi pada proses persalinan, sekitar 5-20% wanita hamil merasa takut saat proses persalinan. Berdasarkan hasil penelitian kualitatif sebagian besar ibu mengatakan bahwa persalinan identik dengan pengalaman yang menakutkan dan sakit. Salah satu cara untuk mengatasi kecemasan adalah terapi nonfarmakologi, yaitu dengan teknik distraksi. Teknik distraksi merupakan pengalihan dari fokus perhatian seseorang ke stimulus lain sehingga dapat menurunkan kecemasan. Teknik distraksi dengan menggunakan metode nonfarmakologis salah satunya dengan terapi Inovasi  Ma-Llow (Maternity Pillow).  Penggunaan Ma-Llow (maternity pillow) yang berhubungan dengan sistem limbik terstimulasi sehingga menghasilkan perasaan dan ekspresi. Hormon endorphine  yang keluar setelah penggunaan Ma-Llow akan berguna mengurangi nyeri dan mengurangi kecemasan. Edukasi kesehatan tentang terapi nonfarmakologi Ma-Llow masih diperlukan untuk meningkatkan kesehatan fisik dan psikis pada hamil dan bersalin. Penggunaan metode seperti ceramah, demonstrasi membantu meningkatkan pengetahuan, sikap dan perilaku masyarakat. Edukasi kesehatan dilakukan pad tanggal 24 dan 31 Agustus 2024 di Puskesmas Rowosari, partisipan dalam kegiatan ini adalah 50 orang ibu hamil. Kegiatan terdiri atas 4 tahap kegiatan, yaitu: (1) pembukaan; (2) Pre Test; (3) Materi tentang Sehat Fisik dan Psikis masa kehamilan, persalinan dengan Ma-Llow; (4) diskusi; (4) penutup. Penggunaan Ma-Llow pada ibu hamil dan bersalin dapat meningkatkan kesehatan fisik dan psikis masa kehamilan dan persalinan.
Can History Bring Reconciliation in Divided Christian Communities?
Authors: Denis Philippe
Published: October 2024

As Elazar Barkan, the founding president of the Institute for Historical Justice and Reconciliation, pointed out, the recounting of history has been exploited to provoke conflict, incite war, and inflame genocides. Can it also be drawn upon to facilitate reconciliation? Indeed, many conflicts have an ideological component which is based on contested views of history. This applies to the Christian churches, starting with the Reformation. Using four case studies, the article argues that “good” history, based on reliable archival and oral evidence, can lay the foundation for a more serene view of the past and lead to reconciliation. It is essential to consider all points of view. The historian must navigate between diverse opinions and emotions, deepening the analysis when there are conflicts of interpretation. The article examines four recent memory debates in the Christian churches: the painful closure of the Federal Theological Seminary in 1993; the silence of the Rwandan churches during the genocide against the Tutsi in Rwanda in 1994; the brutal transfer of a group of black sisters from Newcastle to Montebello in 1939; and race relations and the search for unity in the history of the Lutheran churches of Southern Africa.
A Paradigm Shift in Understanding Overuse Running-Related Injuries: Findings From the Garmin-RUNSAFE Study Point to a Sudden Not Gradual Onset
Authors: Frandsen Jesper Schuster Brandt , Simonsen Nina Sjoerup , Hulme Adam , Jacobsen Julie Sandell , Nielsen Rasmus Østergaard
Published: October 2024

OBJECTIVES: To investigate the proportion of running-related injuries that can be classified as (1) being based on overload with an acute mechanism with a sudden onset, (2) being overuse in the sense they are based on a repetitive mechanism with a sudden onset; and (3) being overuse in the sense that runners gradually develop problems that lead to an injury.

DESIGN: Cohort study with an 18-month follow-up.

METHODS: English-speaking runners aged at least 18 years who were tracking running activities were included. Running-related injury during follow-up categorized into 3 groups: (1) those with overload injury, (2) those with a running-related problem 7 to 28 days prior to reporting a running-related injury, and (3) those sustaining a running-related injury without any preceding problems.

RESULTS: Overload injury accounted for 467 of 1666 injuries (28%), while 1199 injuries were overuse (72%). Among overuse injuries, the proportion of runners having a problem prior to injury occurrence was 6.9% (95% confidence interval [CI]: 5.5%, 8.4%) 7 days prior to injury and 11.1% (95% CI: 9.4%, 13.0%) 28 days prior to injury.

CONCLUSION: Most of the overuse injuries occurring in adult runners may be classified as sudden repetitive overuse injuries rather than injuries that are based on a gradual onset. JOSPT Open 2025;3(1):85-92. Epub 1 October 2024. doi:10.2519/josptopen.2024.0075
Deep Packet Inspection Model Based on Support Vector Machine for Anomaly Detection in Local Area Networks
Authors: Moronke DOSUNMU Margaret , Ayo Femi Emmanuel , Adebayo OGUNDELE Lukman , Ishola TAIWO Abass , Olabisi OLATAYO Timothy
Published: October 2024

Deep packet inspection is a network security solution that identifies and flags anomalous network traffic patterns in a local network environment. Traditional signature-based techniques for intrusion detection are limited in identifying different attacks or completely new kinds, which makes them unsuitable in some situations. In addition, most previous methods for anomaly detection have low detection rate and high false alarm. In this study, a deep packet inspection model based on support vector machine (SVM) for anomaly detection in local area networks was proposed. The proposed method combined the SelectKBest method and SVM for the categorization of anomaly in a local network environment. Results showed that the proposed method outperformed other related machine learning methods with accuracy, precision, recall, and F1-score of 94.81%, 94.03%, 94.13%, and 94.0799%, respectively. The accuracy result shows that most network traffic can be correctly identified by the SVM using the SelectKBest approach, with minimal false positives or negatives.
Optimizing Civil Construction Litigation In Indonesia: A Comprehensive Framework For Efficiency, Expertise, And Equity In Dispute Resolution
Authors: Azizan Akmal , Sophia Sally , Zahra Salma , Perai Nurajam
Published: October 2024

Delays, excessive expenses, and a decline in public confidence come from the specialized nature of civil construction litigation in Indonesia. Several efforts have been made to improve civil construction litigation in Indonesia, such as introducing procedural reforms to expedite case processing times, increasing access to mediation and alternative dispute resolution (ADR), and the occasional involvement of technical experts to assist judges in understanding complex construction issues.    Unresolved problems continue despite current attempts; a complete system redesign is required. This paper attempts to fill such knowledge gaps and provide fresh approaches to civil construction litigation in Indonesia. This study provides a comprehensive strategy to improve litigation effectiveness, efficiency, and professionalism by incorporating worldwide best practices and offering practical solutions. The research takes a methodical look at effective models in the UK, Germany, France, and Japan. It identifies critical issues in the Indonesian setting and develops specialized procedural tools like "Case Management Information Tables" and "Case Management Plan Tables." A long-term vision for the legal framework is also discussed, along with strategic approaches to expert evidence, creating a qualification and assessment system, the participation of active-standing technical advisors, and more. The study produces a versatile and all-encompassing structure for civil construction litigation in Indonesia. The research fills a need in the literature by providing valuable resources and fresh ideas for improving efficiency in legal procedures, bolstering the credibility of expert testimony, establishing stringent qualifying criteria, and encouraging long-term flexibility. The public's faith and confidence in the Indonesian legal system are bolstered due to these contributions, which increase the process's efficiency and justice.
Os dias em que eu e Bobbio não fomos heróis!
Authors: Oliveira José Luciano Góis de
Published: October 2024

O título deste texto não deve se prestar a mal-entendidos. Bobbio tem sido desde os anos 80 do século passado, e continua sendo, um dos meus heróis. No início daqueles anos – exatamente em 1980 – abandonei uma carreira na advocacia que exercia sem muita vocação em Sergipe, onde nasci, me criei e me formei, e vim para o Recife fazer uma pós-graduação em sociologia. Era praticamente um iletrado em ciências sociais; uma espécie de analfabeto funcional por conhecer alguma coisa de marxismo. Mas era só isso. Ou quase só isso.
A questão da cidadania: revisitando Bobbio
Authors: Barreira César Mortari , Granato Marcelo De Azevedo
Published: October 2024

20 anos após o falecimento de Norberto Bobbio, o artigo discute a atualidade de seu pensamento político. Inicialmente são apresentadas uma série de limitações à democracia, ora pela atuação de chefes carismáticos, ora em virtude das restrições impostas pelo mercado. Tendo como ponto de chegada desses processos a perda de substância da cidadania, retomamos algumas passagens de O futuro da democracia, cuja primeira edição completa 40 anos. Nossa hipótese é que essa revisita pode tanto constituir um sismógrafo das frustrações sociais que atravessam o mal-estar da democracia como alargar o repertório de inciativas comprometidas com sua defesa.
Meningocele manqué. Case report of a rare disorder
Authors: Carvalho Ajay Sebastian , Gupta Vijay Kumar , Srivatsava Chinmaya , Dwivedi Deepak
Published: October 2024

A case of meningocele manqué with its management is presented and the literature of this rarely reported condition is reviewed.
A one-year-old child was admitted with a small sac like lesion in the upper dorsal region with a soft swelling in the dorso lumbar region, was also associated with congenital bilateral talipes equinovarus which was being treated by a paediatric orthopedic surgeon.
Methods. Craniospinal MRI was suggestive of dorso lumbar lipomyelomeningocele, and corresponding to the dorsal sinus/sac at DV3/DV4 level there was another tethering seen on the MRI due to a band and associated with syrinx of the dorsal cord below that, s/o meningocele manqué.
Treatment. This patient underwent in 1st stage, DV2 to DV5 laminoplasty, excision of the sinus, durotomy, dissection of the multiple arachnoid cysts, and cutting of the dorsal band. In second stage will undergo surgery for Lipomyelomeningocele
Conclusion: Meningocele Manque is rare, it can present in isolation or associated with other spinal dysraphism. With other spinal dysraphism they can be either at the same or at another location, as was seen in our case. Before operating all cases of spinal dysraphism it is of paramount importance to MRI screen the entire neuraxis and study images thoroughly. In our case along with the dorso lumbar lipomyelomeningocele, there was a Meningocele manqué at DV3/DV4 level. It is essential that the meningocele manqué be addressed first; if not the returning/recoiling cord after de-tethering at the lower level can get tugged/sheared at the tethered meningocele manqué causing deficits.
Growing replacement cow calves
Authors: КОТ А. , РАДЧИКОВ В. , ИЗМАЙЛОВИЧ И.
Published: October 2024

Выпойка ЗЦМ в молочный период положительно влияет на поедаемость кормов, физиологическое состояние и продуктивность ремонтных телочек.
دور القيادة الإدارية في إدارة الأزمات بالمستشفيات الحكومية بالمملكة العربية السعودية أثناء جائحة كورونا
Authors: الشمري هذلول صالح
Published: October 2024

هدفت الدراسة إلى التعرف على أثر القيادة الإدارية على إدارة الأزمات بالمستشفيات الحكومية بالمملكة العربية السعودية أثناء جائحة كورونا. وتمثلت مشكلة الدراسة في السؤال الرئيس التالي: هل للقيادة الإدارية دور في إدارة الأزمات بالمستشفيات الحكومية بالمملكة العربية السعودية أثناء جائحة كورونا؟  استندت الدراسة على عدة فرضيات منها وجود علاقة ذات دلالة إحصائية بين القيادة الإدارية وإدارة الأزمات بالمستشفيات الحكومية بالمملكة العربية السعودية أثناء جائحة كورونا. وتأتي اهمية الدراسة في أثراء المكتبات بمادة علمية وتعتبر إضافة للرصيد الفكري والمعرفي. استخدم المنهج الوصفي، جمعت البيانات من عينة غير احتمالية (ميسرة)، وصممت استبانة لجمع البيانات تم توزيع عدد 150 استبانة، حيث بلغت نسبة الاسترداد 146 استبانة بنسبة 97%، تم بناء نموذج الدراسة وفرضياتها اعتماداً على أدبيات الدارسات السابقة. وكذلك تم الاعتماد على نمذجة المعادلة البنائية (SEM) وفيها استخدم برنامج Amos)) وتم استخدام اختبار ألفا كرنباخ للاعتمادية وأسلوب تحليل المسار لاختبار فرضيات الدارسة. توصلت الدراسة إلى وجود علاقة إيجابية بين القيادة الاوتوقراطية، وإدارة الأزمات بعد (تفتيت الأزمة)، في المستشفيات محل الدراسة، حيث بلغت قيمة بيتا (.398) بمستوى دلالة (011.). ووجود علاقة إيجابية بين القيادة الاوتوقراطية، وإدارة الأزمات بعد (احتواء الأزمة)، في المستشفيات محل الدراسة، حيث بلغت قيمة بيتا  (.398) بمستوى دلالة (011.)، أوصت الدراسة بضرورة الاهتمام بتدريب العاملين وتوفير وسائل المعرفة وخلق فرص الإبداع والابتكار وتحسين الوضع النفسى والمادي لهم.
أثر التخطيط الإستراتيجي في تحسين كفاءة إدارة الأزمات في الشركات الصناعية الأردنية
Authors: الحبابي سالم محمد
Published: October 2024

هدفت الدراسة إلى توضيح أثر التخطيط الإستراتيجي وأبعاده (الرؤيا الإستراتيجية، الرسالة الاستراتيجية، والأهداف الاستراتيجية) في تحسين كفاءة إدارة الأزمات في الشركات الصناعية الأردنية، وذلك باتباع المنهج الوصفي التحليلي. واستهدفت الدراسة الأفراد العاملين في المستويات الإدارية العليا (المدراء العامين ونائبيهم) والمستويات الإدارية الوسطى (مدراء الدوائر) في الشركات الصناعية الأردنية، والمُقدّر عددهم حوالي (145) مديراً. وتم جمع البيانات الأولية من خلال استبيان وُزّع إلكترونياً على أفراد عينة الدراسة، وتحليلها باستخدام أساليب الاحصاء الوصفي، كما تم استخدام تحليل الانحدار الخطي البسيط والمتعدد لاختبار الفرضيات. وتوصلت الدراسة إلى وجود أثر ذو دلالة إحصائية عند مستوى معنويةα≤0.05) ) للأهداف الإستراتيجية في تحسين كفاءة إدارة الأزمات في الشركات الصناعية الأردنية. وأوصت الدراسة بالعمل على تضمين الأزمات في استراتيجية الشركة، وتحديد السيناريوهات المحتملة للأزمات والتحديات ضمن الخطط الاستراتيجية للشركة، وتطوير إدارة الشركة خطط استراتيجية محددة لتحقيق أهدافها، وتحقيق المرونة فيها للتكيف مع التحديات والتغيرات الجديدة.
Features of the use of instrumental methods of problem analysis when implementing lean manufacturing
Authors: Gerasimov A. V. , Mingaleva Zh. A.
Published: October 2024

Successful implementation of the lean manufacturing concept at an enterprise is impossible without the use of special management tools that allow timely identification of problems in the organisation’s activities and causes of their occurrence. However, the increase in uncertainty and unreliability of information creates significant obstacles in making both quick and accurate decisions. The need to select analytical tools to improve the reliability of management decisions requires careful choice of methods for making them. The article analyses the strengths and weaknesses of the Ishikawa cause-effect diagram as an instrumental method of this process for improving production processes. With the help of the comparative analysis based on the use of the Ishikawa diagram, four problems have been identified that may underlie the inhibition of managerial decision-making. The advantages and disadvantages of applying this method in the field of enterprise management and decision-making in conditions of high-speed changes in the external environment are analysed. The most popular modifications of the Ishikawa diagram are considered. It is concluded that the Ishikawa diagram is an effective tool for making prompt and strategic decisions to improve production processes as well as to increase the success of implementing lean manufacturing principles.
Intermolecular Formal [8+3] Cycloaddition of Azaheptafulvene with Bicyclo[1.1.0]butanes Promoted by Lewis Acids
Authors: Li Shi-Wu , Zhu Shijie , Lei Jiaojiao
Published: October 2024

Azaheptafulvenes reacting with bicyclo[1.1.0]butanes (BCBs) through FeCl3 or Sc(OTf)3-promoted formal [8+3] cycloaddition reactions to furnish Nitrogen-containing polycyclic compounds has been developed for the first time. This new reaction tolerated a wide range of azaheptafulvenes and BCBs. Furthermore, the amplification experiments and synthetic transformations of the cycloaddition compounds further highlighted its practicality.
Recent developments in modeling the electric double layer with density functional theory
Authors: Maraschin Mikael , Askari Mahsa , Chauhan Veena , Feistel Luis , Olusegun Samuel , Ortega-Ramos Jessica , Gauthier Joseph
Published: October 2024

Improving our fundamental understanding of charge transfer processes at the electrified double layer currently relies heavily on density functional theory (DFT) simulations, as many in situ and operando spectroscopic methods are hindered by the aqueous electrolyte. However, modeling charged states with semi-local DFT faces serious challenges, and several bifurcating strategies have been developed in an attempt to address them. In this Mini Review, we present a highly abridged overview of some of the challenges faced when modeling charge transfer processes across the electric double layer with DFT. Focusing primarily on charge transfer kinetics, we highlight polarizable continuum models (PCMs) and their use in evaluating energetics in the adiabatic limit of electron transfer, i.e. treating electrons grand canonically during a coupled proton-electron transfer (CPET) reaction. We highlight their use in understanding electrocatalytic processes, in particular the ability to localize transition states at constant potential. Finally, we present our outlook on opportunities for improvement in this critical research area, and nascent methods being developed to test the validity of PCMs and evaluating energetics in the grand canonical ensemble.
Optical Properties of Phenylthiolate Capped CdS Nanoparticles
Authors: Madden Eimear , Zwijnenburg Martiijn A.
Published: October 2024

Using many-body perturbation theory we study the optical properties of phenylthiolate capped cadmium sulifde nanoparticles to understand the origin of the experimentally observed blueshift in those properties with decreasing particle. We show that the absorption spectra predicted by many-body perturbation theory agree well with the experimentally measured spectra. The results of our calculations demonstrate that all low-energy excited-states correspond to a mixture of two fundamental types of excitations, intraligand and ligand to metal charge-transfer excitations. We find that for each excited-state the intraligand excitation contribution is dominant and that bright excited-states, corresponding to the clear peaks in the absorption spectra, have a larger ligand to metal charge-transfer contribution. There are no low-energy bulk-like excitons, excited-states for which both the hole and the excited-electron component are predominantly delocalised over the inorganic core of the particles. Phenylthiolate capped cadmium sulifde nanoparticles appear not to behave like the textbook cartoon picture of quantum dots. We speculate that the observed blueshift is the result of a combination of a Stark-like shift of the intraligand contribution modulated by a change in the charge of the inorganic core and the confinement of the excited electron component of the ligand to metal charge transfer contribution.
Dynamic covalent DNA networks to translate multiple inputs into programmable outputs
Authors: Simone Brannetti , Gentile Serena , Erica Del Grosso , Otto Sijbren , Ricci Francesco
Published: October 2024

Inspired by naturally occurring protein dimerization networks, in which a set of proteins interact with each other to achieve highly complex input-output behaviours, we demonstrate here a fully synthetic DNA-based dimerization network that enables highly programmable input-output computations. Our DNA-based dimerization network consists of DNA oligonucleotide monomers modified with reactive moieties that can covalently bond with each other to form dimer outputs in an all-to-all or many-to-many fashion. By designing DNA-based input strands that can specifically sequester DNA monomers, we can control the size of the reaction network and thus fine-tune the yield of each DNA dimer output in a predictable manner. Thanks to the programmability and specificity of DNA-DNA interactions, we show that this approach can be used to control the yield of different dimer outputs using different inputs. The approach is also versatile and we demonstrate dimerization networks based on two different covalent reactions: thiol-disulfide and strain-promoted azide-alkyne click (SPAAC) reactions. Finally, we show here that the DNA-based dimerization network can be used to control the yield of a functional dimer output, ultimately controlling the assembly and disassembly of DNA nanostructures. The dynamic covalent DNA networks shown here provide a way to convert multiple inputs into programmable outputs that can control a broader range of functions, including ones that mimic those of living cells.
A Heavy Solution for Molecular Thermal Management: Phonon Transport Suppression with Heavy Atoms
Authors: Bro-Jørgensen William , Bay-Smidt Andreas Juul , Donadio Davide , Solomon Gemma C.
Published: October 2024

Thermal management in molecular systems presents challenges that require a deeper understanding of phonon transport, an essential aspect of heat conduction in single molecule junctions. Our work introduces the use of heavy atoms as a strategy for suppressing phonon transport in organic molecules. Starting with a 1D force-constant model and density functional theory calculations of model chemical systems, we illustrate how increasing the mass of a central atom affects the phonon transmission and conductance. Following this, we turn our attention to the chemically accessible systems of metallapolyynes and extended metal atom chains (EMACs). Our findings suggest that several of the studied EMACs exhibit thermal conductance either near or below a recently proposed threshold of 10 pW/K – a crucial step towards reaching high thermoelec- tric figure of merits. Specifically, we predict that the molecule MoMoNi(npo)4 (NCS)2 has a thermal conductance of just 8.3 pW/K at 300 K. Our results demonstrate that conceptually simple chemical modifications can markedly reduce the thermal conductance of single molecules; these results both deepens our understanding of the mechanisms driving single-molecule phonon thermal conductance and suggest a path towards using single molecules as thermoelectric materials.
RNA-Based Aptamer Targeting Clusterin Protein as a Diabetes Biomarker
Authors: Batta Irene , Sharma Gaurav
Published: October 2024

Clusterin protein is primarily used as a diabetes biomarker and can be used to detect cell density in diabetes. A lower β cells are an early sign of type 1 diabetes. Aptamers are single-stranded nucleotides that bind the target protein and are prevalent in disease diagnosis and targeted therapy. Recently, aptamer targeting clusterin protein has been developed as a biomarker of the β cells. We hypothesize that the rigid clusterin protein should have specific amino acids interacting with the particular aptamers. In this research work, we have performed in silico simulations to find the optimal aptamer capable of binding to the clusterin protein and can be used as a biomarker in diabetes. Specifically, we have performed molecular docking simulations to find the clusterin-aptamer binding complexes. These aptamers were selected based on their interactions with the clusterin protein. Phylogenetic analysis shows that the aptamers class is bifurcated into two sections. All the results were validated using the GrASP web server, which shows the aptamer binding region on the protein's surface. The finding indicates that the aptamer binds to clusterin and could potentially be used as a diabetes biomarker.
THE EFFECTIVENESS OF USING BLENDED LEARNING STRATEGY IN THE ACADEMIC ACHIEVEMENT BY SEVENTH-GRADE BASIC STUDENTS IN THE SUBJECT OF KURDISH LANGUAGE
Authors: Saeed Diyar
Published: October 2024

The current study aims  to identify the effectiveness of using the blended learning strategy in the academic achievement of  seventh-grade students in the Kurdish language subject.
The research sample consisted of (114) male and female students from the seventh grade in basic education schools for boys and girls in the city of Zakho for the academic year (2022-2023). It was chosen intentionally by stratified random method from the research community according to the gender variable, then the researcher divided the sample into four equal groups in several  variables based on the factorial experimental design (2X2) in the variables of teaching method and gender. The two experimental groups studied the Kurdish language subject according to the blended learning strategy, while the two control groups studied the same subject traditionally. The researcher verified the validity of the content of the test and extracted its psychometric characteristics as well as its stability. After collecting data from the research sample and processing it statistically using the two-way factor analysis of variance test according to the variables of gender, teaching method, and the interaction between them, the results indicated:
1- There is a statistically significant difference at the level (0.05) between the averages of the Kurdish language achievement among the members of the research groups according to the gender variable in favor of females and the method in favor of the blended learning strategy.
2- There is no statistically significant difference at the level (0.05) between the averages of the members of the research groups in the achievement of the Kurdish language according to the interaction of the variables of gender and method.
In light of the results, the researcher came out with several  conclusions, including the possibility of applying the blended learning strategy in teaching the Kurdish language to students in basic education. The researcher also put forward  some recommendations and proposals in the form of titles for future research.
PPP3CB overexpression mediates EGFR TKI resistance in lung tumors via calcineurin/MEK/ERK signaling
Authors: Gazzeri Sylvie , Zubchuk Nadiia , Montaudon Elodie , Nemati Fariba , Huot-Marchand Sarah , Berardi Giulia , Pucciarelli Amelie , Dib Yassir , Nerini Dylan , Oddou Christiane , Pezet Mylène , David-Boudet Laurence , Ardin Camille , de Fraipont Florence , Maraver Antonio , Girard Nicolas , Decaudin Didier , Toffart Anne-Claire , Eymin Beatrice
Published: October 2024

Despite initial high response rates to first-line EGFR TKI, all non–small-cell lung cancer (NSCLC) with EGFR-activating mutation will ultimately develop resistance to treatment. Identification of resistance mechanisms is critical to adapt treatment and improve patient outcomes. Here, we show that aPPP3CBtranscript that encodes full-length catalytic subunit 2B of calcineurin accumulates in EGFR-mutant NSCLC cells with acquired resistance against different EGFR TKIs and in post-progression biopsies of NSCLC patients treated with EGFR TKIs. Neutralization ofPPP3CBby siRNA or inactivation of calcineurin by cyclosporin A induces apoptosis in resistant cells treated with EGFR TKIs. Mechanistically, EGFR TKIs increase the cytosolic level of calcium and trigger activation of a calcineurin/MEK/ERK pathway that prevents apoptosis. Combining EGFR, calcineurin, and MEK inhibitors overcomes resistance to EGFR TKI in both in vitro and in vivo models. Our results identify PPP3CB overexpression as a new mechanism of acquired resistance to EGFR TKIs, and provide a promising therapeutic approach for NSCLC patients that progress under TKI treatment.
Romancista negra intérprete da nação:
Authors: Rodrigues Miranda Fernanda
Published: October 2024

Ruth Guimarães (1920-2014) foi uma intelectual e escritora intérprete do Brasil. Em seu único romance, “Água funda” (1946) refletiu principalmente o tempo nacional como uma matriz da colonialidade. Na primeira parte deste artigo, apresento a trajetória da autora negra e as consequências do apagamento que sofreu para sua recepção contemporânea. Na segunda, analiso alguns aspectos do romance, destacando a elaboração narrativa como condutora de uma inscrição afro-diaspórica que suscita novas interpretações acerca da nação.
Escritas de mulheres negras:
Authors: DA SILVA SOUZA FLORENTINA DA
Published: October 2024

O presente ensaio, a partir de leitura de textos de escritoras negras contemporâneas, propõe-se a apresentar um breve panorama dos exercícios empreendidos pelas escritoras negras para inserir-se no quadro de produção literária brasileira através da criação de escritas que recusam a estereotipia e a normatização de suas experiências.
Dostoiévski em podcast
Authors: Gonçalves Jean Carlos
Published: October 2024

Esse artigo tem como objetivo apresentar reflexões sobre as relações entre discurso teatral e dialogismo na obra O sonho de um homem ridículo (Dostoiévski, 1877) em sua versão para podcast, produzido pelo canal Rádio Trombeta em 2021 e disponível em diversas plataformas digitais. O texto situa a transposição da obra literária para o formato podcast, ao mesmo tempo em que apresenta potencialidades para uma educação estética da escuta.
O monologismo discursivo da elite intelectual ocidentalista russa em Uma história desagradável, de Fiodor Dostoiévski (1862)
Authors: Perroni Otávio Augusto Buzar , Barros de Sousa Lima Elizabete
Published: October 2024

Uma história desagradável trata do embate entre a elite e o povo russos, ficcionalizado nos personagens Pralínski – símbolo do alto funcionário, representante da classe modernizadora liberal – e Pseldonímov – subordinado, portador dos costumes populares arraigados na tradição eslava. Este artigo investiga as relações discursivas entre as classes sociais representadas no conto. Para isso, invocam-se especialmente as teorias de Mikhail Bakhtin acerca da carnavalização e do dialogismo, categorias literárias que, segundo o autor, servem como elemento de contato entre indivíduos.
O mito de Dostoiévski
Authors: Américo Ekaterina Vólkova , Brito João Paulo de Oliveira
Published: October 2024

Com base na série cinebiográfica russa Dostoiévski (2010), propomos analisar a “mitologização” de Fiódor Dostoiévski, ou seja, o processo de elevação do autor ao patamar de mito sob a imagem de profeta. Para tanto, exporemos algumas das mais relevantes produções cinematográficas relacionadas ao escritor e especificaremos pontos importantes para a análise da série. A partir de estudos sobre biografia, mito e cinema de autores como Pierre Bourdieu, Michel Foucault, Iúri Lotman e Joseph Campbell, examinaremos diferentes perspectivas que traçam o caminho biográfico do romancista rumo ao mito.
Glosas sobre um "flâneur" confesso - miradas benjaminianas na "Crônica de Petersburgo"
Authors: Dusi Rocha Fernando Antônio
Published: October 2024

Este ensaio pretende examinar um dos quatro folhetins assinados por Dostoiévski e publicados em 1847, por meio dos quais este escritor assume um confesso papel de um flâneur na São Petersburgo czarista e revela uma crônica ensaística à altura de sua originalidade como pensador e visionário, ao traçar croquis de tipos da sociedade russa e criar com o leitor intimidade suficiente para suscitar desassossegos sociais e metafísicos. Propõe-se, também, a flagrar o narrador flâneur sob a mirada de Walter Benjamin e interpelar este caminhante-folhetinista sobre a fragilidade da existência e o hiato entre o sujeito histórico e o sujeito sonhador.
Memórias dos palácios de cristal
Authors: Vianney Cavalcanti Nuto João
Published: October 2024

Este ensaio analisa o Palácio de Cristal e ambientes afins em narrativas de Tchernichevski, Dostoievski e Zamiatin, demonstrando como cada “palácio de cristal” forma um tipo de cronotopo: o cronotopo do progresso capitalista, o cronotopo da utopia socialista e o cronotopo da distopia. Desta maneira, cada cronotopo remete alegoricamente a tensões ideológicas em torno do desenvolvimento tecnológico, seus usos e sentidos.
Palavras-chave: Palácio de Cristal, Que fazer?, Memórias do subsolo, Nós
O sonho de um homem ridículo
Authors: Brait Beth
Published: October 2024

O sonho de um homem ridículo”, de Dostoiévski, publicado em 1877, é um texto que conhece inúmeras adaptações no Brasil e no exterior. Na dupla pandemia brasileira, sanitária e política, o texto também recebeu várias versões em diferentes mídias. Neste artigo, o objetivo é analisar a leitura audiovisual, que integrou o projeto digital Abismos de Dostoiévski (Ciclo de encontros), realizado em abril de 2021. Nele é possível reconhecer a profundidade filosófico-literária do escritor russo, motivando um diálogo com a contemporaneidade brasileira, por meio da criatividade artística que, recorrendo à internet, encontra uma forma de driblar a angustiante impossibilidade dos encontros presenciais, na arte e na vida.
A tessitura polifônica de Crime e castigo
Authors: Bezerra Paulo
Published: October 2024

Com base em conceitos de Mikhail Bakhtin, em diálogo com observações de Karl Marx sobre o Capitalismo, este ensaio analisa a construção polifônica do romance Crime de Castigo, de Dostoiévski.
A Modernidade Estética de Cortázar e Escher
Authors: Quintiliano Pereira Deise
Published: October 2024

Esse ensaio propõe uma análise do conto de Julio Cortázar “La noche boca arriba”, coadjuvada pelo contraponto com duas litografias de M. C. Escher, pois ambos os autores problematizam questões referentes à pluralidade de possibilidades de apreensão do mundo, sobretudo na relação espaço-tempo. O dialogismo entre arte e literatura é mediado por informações colhidas na teoria da relatividade einsteiniana, instaurando uma triangulação perspectivista mais condizente com as propostas do escritor argentino e do artista gráfico holandês, criadores de produtos estéticos modernos.
Ruína do corpo narrativo na obra derradeira de D. H. Lawrence
Authors: Albus Maria Lua , Felix José Carlos
Published: October 2024

D. H. Lawrence morreu em 1930, de tuberculose. Escritor de corpos embricados no ciclo de criação e destruição da natureza — ciclo cuja reificação é epitome da sociedade industrializada — em sua lenta e febril marcha para a morte Lawrence esboça uma metafísica da ruína. Este artigo traz dois ensaios, um romance e um poema seus, pensados como textos nos quais a ruína do romance, mais do que tema, é mote da impossibilidade de a narrativa constituir-se como experiência e escrita totalizante. A análise é atravessada por Theodor W. Adorno na dialética do romance, e na tensão entre cultura e morte.
Nature Speaks, Poetry Responds
Authors: Vieira Mauricio
Published: October 2024

The article explores the ancient link between plants and poetry, evoking poetry’s early connection with healing rituals and its expression throughout history until the present day, when the climate crisis makes imperative a closer proximity to nature by virtue of the feelings and sensations that poetry can invoke in regard to nature’s beauty and power of creation
Marxismo e Feminismo
Authors: Del Rio Bárbara
Published: October 2024

Marxismo e Feminismo: resenha de O patriarcado do salário (Boitempo, 2021), de Silvia Federici
“Carioca”, de Chico Buarque:
Authors: Leite Carlos , De Oliveira Prusch Vinícius , Baumbach Manica Pedro
Published: October 2024

O trabalho apresenta uma análise da canção “Carioca”, lançada por Chico Buarque como parte do álbum As Cidades, de 1998. Argumenta-se que haveria certa sinuosidade em seu eu cancional que indicaria um gozo a partir da transformação de pessoas em mercadoria. Entre o pregão de rua e a prostituição de menores, a faixa de Chico estaria imiscuída profundamente nessas tensões, o que justificaria uma leitura mais cuidadosa dessa forma estética, que seria menos transparente que aparenta.
O romance epistolar europeu no século XVIII: da sentimentalidade ao amor filosófico
Authors: Medeiros Constantino Luz de
Published: October 2024

O artigo analisa o romance epistolar e seu papel na transição dos códigos culturais da semântica do amor, e na formação sentimental do público burguês no século XVIII europeu. Busca-se refletir sobre as principais características desse longo processo de formação das classes burguesas através do romance epistolar, observando o modo como os romances Pamela (1740), de Samuel Richardson, Júlia ou A Nova Heloísa, de Jean-Jacques Rousseau (1761), e Lucinde (1780)¸ de Friedrich Schlegel contribuem para a compreensão do fenômeno.
O circo amazônico: o conflito da paisagem e o herói saltimbanco
Authors: Fernandes Marijane Costa , Aleixo Marcos Frederico Krüger
Published: October 2024

A literatura produzida no Amazonas envolve dois polos que favorecem ora o encanto pelo local, ora o distanciamento. Destacam-se a floresta e a cidade como extremos veiculados nas prosas e poesias da região, pois cada sociedade aprende princípios e valores de forma distinta, tendo o prazer da vivência consagrado por um ambiente que inspira confiança e paz. Nem sempre esse ambiente amistoso é visto na habitação da floresta, porquanto, para muitos, a cidade é o lugar da civilização. Então, analisa-se o conflito de Zé Raimundo, em No circo sem teto da Amazônia, de Ramayana de Chevalier.
Lavoura arcaica em perspectiva nietzschiana:
Authors: Gonçalves Jivago Araújo Holanda Ribeiro , De Oliveira Luizir
Published: October 2024

Buscou-se discutir no presente trabalho, através de uma abordagem interdisciplinar entre literatura e filosofia, a questão do corpo em Lavoura arcaica (1975), de Raduan Nassar. Nesse intuito, o horizonte interpretativo foi composto pela produção filosófica de Friedrich Nietzsche. Com isso, tentou-se evidenciar a confluência de uma perspectiva crítica, entre literato e filósofo, sobre os aspectos do corpo que, em última análise, viabilizará uma crítica da cultura e seus respectivos valores.