bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of Food Purchase Price in Tourism Objects in The City of Sigli
Authors: Benazir Benazir , Fuadi Zulfa
Published: February 2023

This research was conducted to find out the determination of the buying and selling price of food at the Sigli city tourist attraction. Data collection techniques using interviews, observation and documentation. Data analysis in this study will use qualitative data analysis which is constructive, develops and discovers social theories. From the results of this study it was found that there were differences in pricing at the Sigli City tourist attraction. Sellers differentiate prices between one buyer and another by looking at the characteristics of the buyers. If the buyer is from the local area or visitors who frequently visit, the price given is the standard price and if the buyer is considered a new seller, the seller gives a higher price compared to buyers from the local area. According to Islamic law, the practice of buying and selling is carried out by the seller with discriminating between buyers is permissible as long as traders do not take advantage in a way that is prohibited by Islamic law and between sellers and buyers are consensual and mutually willing without any coercion.
Status of Adopted Child Turned into Mahram According to Syafi'i Fiqih
Authors: Al-Furqaan Muhammad , Mustafa Muhammad Al
Published: February 2023

Adopted children who have grown up will have certain genitalia boundaries with adoptive parents. This causes the role of adoptive parents to not be realized optimally and the rights of adopted children cannot be fully fulfilled. Conversely, when adoptive parents do not pay attention to Islamic values in the practice of adopting children, this is also strictly prohibited in religion, and is considered very fatal, because it is included in the practice of tabanni during the Jahiliyya era. This research was conducted to answer problems that are currently occurring in the practice of adoption, in the form of what is the status of adopted children in Islam, how is the process for adopted children being made mahram status according to Syafi'i fiqh, and what is the law that applies to adopted children. This research is included in the category of library research. The author uses a normative approach that is descriptive in nature. The results of the research are presented by the author in the form of solving problems that occur between adoptive parents and adopted children by changing the status of adopted children to become mahrams, namely: by breastfeeding when they are child, adopting children from husband or wife relatives, and marrying adopted children. Furthermore, when the status of an adopted child has been changed to that of a mahram, then what has legal consequences is only the boundaries (aurat) of the adopted child. Meanwhile, in matters of inheritance, marriage guardianship, and lineage, nothing changes even though the adopted child has the status of a mahram. However, considering that their relationship is familiar and since childhood the adopted child has been with the adoptive parent, feeling that something is missing if the adopted child's rights are differentiated from those of his biological child, then the solution that can be made for inheritance is a mandatory will or inheritance testament so that the adopted child can still feel the inheritance those left behind and taukil marriage guardians to adoptive parents for matters of marriage guardians so that they can feel the guardianship of their adoptive parents. As for the issue of lineage, this cannot be contested in any way, because pure lineage was given by biological parents which cannot be changed even by tabanni.
Accountability in The Maqashid Sharia Perspective
Authors: Darma Satria , Sunardi Sunardi , Alimuddin HM Alimuddin HM
Published: February 2023

This study aims to analyze accountability in the perspective of maqashid sharia. In this study using exploratory study method, namely descriptive analysis in analyzing secondary data related to these problems, by determining the theory of Islamic companies, agency theory and information asymmetry, and the philosophy of justice in Islamic law. The results of the research show that accountability is carried out by the company as a form of accountability for the trust given. The goal is to create justice and prosperity for all parties.
Rights and Obligations of Husband and Wife According to Islamic Law in Constructing Sakina Family
Authors: Ali Muhammad Ikbal
Published: February 2023

This research aims to know the rights and obligations of husband and wife in building a sakinah family. The method used in this study is the library research method with a normative approach. The research results show that Husband and wife understand that the position of wife and husband in the household is the same, but have different rights and obligations, although on the other hand the community understands that the position of the wife in the family is under the husband, they understand this from the understanding of salaf fiqh which states that the wife must uphold high her husband with honor and glory. The concept of Islamic marriage teaches that the rights possessed by husband and wife are in balance with the obligations imposed on them, a husband or wife has balanced obligations. To realize a harmonious, sakinah and peaceful family, this can be done by fostering the appreciation of Islamic religious teachings, fostering mutual respect, fostering an attitude of efficient living, and fostering an introspective attitude of each husband and wife.
La audiencia de The Newsroom (HBO) en España: perfiles, identificación y roles periodísticos
Authors: Novoa-Jaso María Fernanda , Serrano-Puche Javier
Published: February 2023

Este artículo presenta los resultados de una encuesta realizada a 719 seguidores de The Newsroom (HBO) en España. El estudio examina la identificación con los personajes favoritos y el reconocimiento de roles periodísticos en la ficción audiovisual. Los resultados presentan seis perfiles diferenciados de fans en función de su opinión sobre la serie (realista, idealista, critica o didáctica) y su ocupación laboral (comunicadores, estudiantes o público general). Entre los seguidores, que tienen una implicación emocional fuerte y positiva con la serie, predomina la percepción de que ésta ofrece una visión idealizada de la profesión. Los roles más reconocidos en el relato serial son los de periodista participativo, periodista como perro guardián y movilizador de la ciudadanía.
Nadzieja z Melos. Przyczynek do debaty nad pojęciem elpis
Authors: Jaśtal Jacek
Published: February 2023

Na przełomie 416/15 r. p.n.e. będące u szczytu potęgi Ateny całkowicie zniszczyły Melos, niewielką polis na Morzu Egejskim. Relacjonując poprzedzające inwazję negocjacje, Tukidydes (Wojna peloponeska, V 84–116) wielokrotnie przywołuje pojęcie nadziei (elpis). Mieszkańcy Melos wiążą ją z rozsądkiem Ateńczyków, ze wspar­ciem Sparty, ze szczęśliwym zbiegiem okoliczności, z zasadami sprawiedliwości, wreszcie – z pomocą bogów. Wszystkie te oczekiwania jednak zawodzą. Tukidydes zdaje się sugerować, że posiadanie nadziei jest zawsze nieracjonalne, co jego zdaniem potwierdzają nie tylko losy Melos, ale także samych Aten, ostatecznie pokonanych w wojnie peloponeskiej przez Spartę. Książka Nadzieja z Melos. Przyczynek do debaty nad pojęciem elpis stanowi polemikę z Tukidydesem. Autor stara się zrozumieć, na czym polega nadzieja w sytuacjach ekstremalnych, jaką pełni funkcję w naszym życiu, co odróżnia nadzieje fałszywe od nadziei uzasadnionych. Książka rozpoczyna się od analizy opowieści Hezjoda o nadziei zamkniętej w puszce Pandory. Następnie autor śledzi dzieje pojęcia elpis w greckiej mitologii, literaturze i filozofii. Na przykładzie fikcyjnego władcy Melos, Agathona, pokazuje różne ujęcia nadziei oraz różne pełnione przez nie funkcje – poznawcze, motywacyjne, moralne oraz odnoszące się do poczucia sensu i potrzeby szczęścia. Klucza do zrozumienia postawy żywienia nadziei szuka w koncepcji uzasadnienia sądów głoszonej przez sofistów, psychologii działania Platona, koncepcji cnoty u Arystotelesa oraz u stoików. Przywołuje także różne typy nadziei: nadzieję fundamentalną, której elementy pojawiają się już u Heraklita, i nadzieję radykalną, opisaną przez współczesnego filozofa J. Leara. Ostatecznie za najważniejsze uznaje tę rolę nadziei, która wiąże się z przekonaniem o moralnej wartości podejmowanych działań, nawet jeśli w wyniku różnych splotów okoliczności (traf moralny) okażą się one błędne.
Azithromycin Treatment in COVID-19 is Not Associated with Clinical Course Shortening, But it Is Associated with a Reduction in Mortality. A Case Control-Study Paired By Sex, Age Group, Chronic Diseases and Severity
Authors: Turabian Jose Luis
Published: February 2023

Background: Azithromycin (AZT) has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. Objective: To assess the association between exposure to AZT in patients with COVID-19, both admitted to the hospital and treated as outpatients, with respect to the duration of their clinical course and mortality. Methodology: An observational and retrospective case control-study paired by sex, age group (> and = <65 years), presence or absence of chronic diseases, and severity (presence or absence of pneumonia) was conducted March 15, 2020 to March 15, 2021, in a general medicine office in Toledo, Spain. Results: 19 cases and 19 controls were included. 26% of the cases and 42% of the controls had a positive clinical result (improvement or clinical cure before 13 days of the onset of the disease) (Fisher exact test = 0.1051; Paired OR = 0.4545 (Confidence intervals at 95%: 0.1579, 1.308). In the 19 cases there were no deaths vs. 2 deaths in the control group (Fisher exact test = 0.0001; paired OR = 0.1053 (Confidence intervals at 95 % = 0.02452, 0.4519). Conclusions: In the context of general medicine in Toledo (Spain), AZT did not shorten the duration of clinical symptoms, but it was shown to be a protective factor against mortality. Due to the limitations of the study design, the results should be considered with caution and the use of AZT in COVID-19 should be probably restricted, to date, to patients in whom there is an antimicrobial indication.
Evolving Pattern of Remdesivir Prescribing During the COVID-19 Pandemic: Outcome and Cost Implications
Authors: Sophonsri Anthony , Ny Pamela , Nieberg Paul , Wong-Beringer Annie
Published: February 2023

Purpose: Remdesivir has become a part of the treatment standard for patients hospitalized with COVID-19 since its initial availability under the Expanded Access Program in March 2020. Here, we describe our evolving experience with remdesivir utilization during the pandemic. Methods: Medical records of patients prescribed remdesivir during March to December 2020 at a community teaching hospital were reviewed for baseline characteristics, clinical presentation and management, outcomes, and cost of remdesivir treatment. The pattern of remdesivir prescribing was compared pre- and post-formulary addition of the drug for use in hospitalized COVID-19 patients. Results: Criteria for remdesivir use evolved from requiring mechanical ventilation to requiring low oxygen supplementation during the study period. A 3.5-fold increase in remdesivir use outside of criteria was observed after formulary addition when much of the prescribing was shifted from Infectious Diseases (ID) and Pulmonary Critical Care Medicine (PCCM) to the Internal Medicine service. Compared to Pre-formulary patients, Post-formulary patients had lower requirements for oxygen supplementation and more achieved early clinical response with <5 days of remdesivir (29.7% vs. 9.2%, p<0.0001), had significantly shorter time to stability (median 4 vs. 6.5 days, p<0.0001) and length of stay (6 vs. 10 days, p<0.0001), and lower mortality (9.9% vs. 15.5%, p=0.19). None of the patients who achieved early response and received <5 days of remdesivir had a COVID-related readmission or emergency department (ED) visit within 30 days. Potential cost savings per 100 patients is estimated at $35,000 with strict adherence to criteria and an additional $15,444 when treatment duration is shortened to 4 days in the early responders. Conclusion: Prescribing of remdesivir outside of criteria increased after it was no longer restricted to ID or PCCM specialists upon formulary addition. Provider education is needed to improve adherence to criteria-based prescribing. Shortening treatment duration in early responders can lessen healthcare resource utilization and cost without negatively impacting patient outcomes.
Preliminary negotiation of the dispute as a vision of effective judicial proceedings
Authors: Václavová Veronika
Published: February 2023

The presented article discusses the new institution of the recoded civil process, namely the institution of preliminary discussion of the dispute, the purpose of which is to conclude a settlement and its regulation in Act no. 160/2015 Coll. Slovak Republic, The Civil Procedure Code, as amended. The aim of the contribution is to point out the potential of the given institute and its validity in the Slovak legal order, while the author emphasizes the need for its greater use in judicial practice, while based on her own experience, theoretical starting points and codes, she will evaluate the importance of introducing the given institute into the Slovak legal order. The author is also of the opinion that through the preliminary discussion of the dispute, the court proceedings can be made more efficient since even though the purpose of the given institute is primarily to conclude a settlement, its goal is also to speed up the dispute proceedings and ensure its procedural economy.
18th World Lake Conference. Governance, Resilience and Sustainability of Lakes for a Better Society
Authors: Shah Afroz Ahmad , Achenef Hailemariam Zewudu , Flores Ponce Ángel , Naik Rajashree , Reyes Cisneros Juan Miguel , Zavala Sánchez Mayela Janeth , Maribao Mary Grace , Tsujino Haruka , Külköylüoğlu Okan , Supriyanto Supriyanto , Kakavipure Dilip Keshav , Velkova Jordanoska Lydia , Sharip Zati , Nirbhavane Gangotri , Austria Kathleen Joyce , Posadas Royette , Nakai Katsuki , Verduzco Garibay Marycarmen , Rivera García Jonatan Ernesto , Magadza Christopher , Mahapatro Debasish , Mizuno Toshiaki , Banderas Tarabay Alfonso Guillermo , Yazawa Taishi , Chacón Torres Arturo , Pérez Sillero Julia , Sauno Contreras Frida , Apostolova Nadezda , Casadei Stefano , Espinosa Arias Jesús Alberto , Jacobo Escamilla Alma Itzel , Díaz Gómez Andrea Romina , Natuel Fátima , Caldera Hernández Adriana Yarenin , Santander Monsalvo Jacobo , Akogwu Simeon , bin Kasim Mahd Fadhil , Roblero Escobar Claudia Ximena , Rodríguez Castrejón Ulises Emiliano , Salut Zandra , Grima Olmedo Juan , Touchant Lauren , Bhargava Mansee , Raini Jackson , Bernal Diego , Domínguez Alfaro Nancy Nayeli
Published: February 2023

The 18th World Lake Conference, entitled “Governance, Resilience, and Sustainability of Lakes for a Better Society” was held virtually from November 9th to 11th, 2022 at the University of Guanajuato, Mexico. This forum was designed with the primary objective of providing a space where scientists, professionals, students, managers, and practitioners could propose, share, and learn about studies, strategies, and actions which enhance the management of lakes around the world. Different activities were contemplated and scheduled in the organization of this forum, such as conferences, special sessions, technical sessions, and workshops where 194 distinguished investigators and participants shared the results of their research and the knowledge they have gained over the years.
Evaluation of Prevalence and Predictors of Waterpipe (Shisha) use among Pre-medicine and Pharmacy students in the Muscat Region- A Pilot Study
Authors: Salam Nazmi Abdul , David Pratap , Ahuja Alka , Alam Khan Shah , Al Hakak Marwa , Francis Joseph
Published: February 2023

Tobacco epidemic has become one of the biggest public health threats to the world as it kills more than 8 million people annually. The purpose of this study was to assess the prevalence and predictors of waterpipe (shisha) use among Pre-medicine and Pharmacy students in the Muscat region. A validated questionnaire containing 32 questions on shisha use, knowledge & attitudes concerning shisha use, cessation, initiation trends and exposure to second hand smoke (SHS) was self-administered to 140 students. Approximately half of the students were Omanis and 19.4% of the students had smoked shisha at least once. About 22.9% of the students, felt that smoking made them more comfortable in social gatherings. Approximately 21.6% students smoked in places outside their homes, contributing to SHS. The prevalence of shisha and cigarette smoking were 2.9% and 4.3% respectively. Males and non-Omanis (64.7% and 42.4%) were found to be more susceptible to initiate smoking within a year. This study indicated that shisha smoking and cigarette smoking are on the rise among young adults. Hence, there is a need to educate students about the harms of shisha smoking, to quit smoking and to protect the non-smokers from being initiated into this vicious habit.
Verification of Uniformity of Dosimetric Characteristics of Couch Tops in Proton Radiation Therapy
Authors: Vladimirkin S. A. , Kiselev V. A. , Demidova A. M. , Udalov Yu. D. , Gritsenko S. E. , Oraskina A. A.
Published: February 2023

In proton therapy the couches used for patient positioning and alignment can affect the uncertainty in the dose distribution from the applied proton beam. In order to limit the additional uncertainty of the proton range, it is necessary to know the determined water equivalent thickness (WET) of the couch top and carefully reflect it in the calculations of the dosimetry planning system. The method presented in this article is based on the difference in the measured depth of the proton beam detected by the multilayer ionization chamber with the beam passing through the couch top and without passing through it.

A range shifter (proton beam modifier) installed in the nozzle with the known WET for evaluating couch tops before commissioning was used in this research work. A nozzle is a proton beam delivery system consisting of quadrupole magnets, ionization chambers and an X-ray tube. CT scans were also acquired to evaluate the internal homogeneity of the test couch tops.

Several kVue couch inserts Proton one (Qfix Systems, Avondale, PA) were evaluated in this study. The results show that the inserts are largely interchangeable for this type of design and the use of the range shifter during treatment, using gantry angles with the proton beam passing through the couch top, does not affect its WET, adding a deflection of approximately 0.1 mm. It was also determined that the reproducibility of the WET determination method has a deviation less than ±0.03 mm. In conclusion, the described above method of couch top testing before commissioning in proton therapy can also be applied to other patient immobilization systems.
Improvement of Proton Irradiation Effectiveness of Human Lung Carcinoma Cells A 549 in the Presence of Gold Nanoparticles
Authors: Rzyanina A. V. , Mitsyn G. V. , Shvidkij S. V. , Molokanov A. G. , Shipulin K. N. , Agapov A. V. , Gaevsky V. N. , Khassenova I.
Published: February 2023

Purpose: To study was to study the effect of GNP nanoparticles on tumor cells of human lung carcinoma A 549 when irradiated with protons.

Materials and methods:

Cell culture: Human lung carcinoma cells A 549.

Gold nanoparticles Au/PEG 6000/W 200/30 nm: A colloidal solution of gold nanoparticles purchased from the firm M 9 Nanomaterials & Technologies was used in the work.

Proton irradiation: The irradiation of cells was carried out on a therapeutic proton beam in the Medical and Technical Complex of the Laboratory of Nuclear Problems Joint Institute for Nuclear Research.

Determination of radiosensitivity of cells: By determining the clonogenic survival of cells.

Determination of the genotoxic activity of nanoparticles under the action of proton irradiation: investigated using a micronucleus test with blocking cytokinesis. The genotoxicity of gold nanoparticles was estimated by the number of micronuclei per 1000 binuclear cells. Micronucleus were counted only in binuclear cells. At least 1000 binuclear cells were calculated for each dose, experiments were carried out in three repeats.

Results: The frequency of micronucleus formation indicates an increase in the genotoxic effect of nanoparticles when irradiated with protons at a dose of 2 Gy. Proton irradiation caused an increase in the frequency of micronucleus formation depending on the concentration of nanoparticles. When irradiated with protons at a dose of 2 Gy in the presence and absence of nanoparticles, the difference in the frequency of micronucleus formation for the concentration of nanoparticles was 2.5 mg/ml – 1.1; for 5 mg/ml and 10 mg/ml – 1.2; for 15 mg/ml – 1.3 and for 30 mg/ml –1.5. Cell survival curves reflect a decrease in their survival rate when metal nanoparticles with high Z are added, which reflects the occurrence of radiosensitization effects. The gain for 10 % and 50 % survival rates is 1.4 and 2.5, respectively.

Conclusions: Under the influence of proton irradiation, the genotoxic activity of gold nanoparticles in human lung carcinoma cells A 549 increases, depending on their concentration. The survival rate of human lung carcinoma A 549 cells irradiated with protons in the presence of gold nanoparticles decreases.
Evaluation of the Quality and Comparison of Dosimetric Parameters of Plans for Craniospinal Irradiation Using VMAT Method at Varian TrueBeam and Varian Halcyon Accelerators
Authors: Gumbatova A. E. , Ovsyannikov A. V. , Lebedenko I. M. , Luzina I. I.
Published: February 2023

Purpose: To carry out a comparative analysis of the dosimetric characteristics of plans for craniospinal irradiation (CSI) performed by the VMAT technique on Varian TrueBeam and Halcyon electron accelerators. Material and methods: Comparison of dose distributions was carried out for a group of 5 patients with tumors of the central nervous system. Contouring and planning were in Eclipse version 15.6. The following dose characteristics were calculated and evaluated: homogeneity index (HI), conformity index (CI), target coverage (CO) and constraints (lenses, esophagus, lungs, heart, liver, bowel bag and kidneys). Patient-Specific QA was performed to verify the consistency of the dose distribution calculated in the planning system and obtained at the accelerators. Results: For all CSI plans the target coverage metric was D98>95 % and constraints for critical organs were obtained. Homogeneity index was HI<=0.12 for two accelerators. The mean value of the CI conformity index was 1.09 for the TrueBeam accelerator, and CI=1.12 for the Halcyon. Gamma analysis showed results within tolerance both plans at TrueBeam and Halcyon. Conclusions have been made about the advantages and disadvantages of CSI on TrueBeam and Halcyon electron accelerators. Conclusion: It is possible to treat patients with the CSI method on the Halcyon accelerator using the VMAT method with the same quality as on the TrueBeam accelerator.
Experience in the Treatment of Breast Cancer Using Tunnel Type Linear Accelerator
Authors: Uvarov A. S. , Shindiakin E. V. , Platonov V. K. , Zemko M. V. , Galchenko L. I.
Published: February 2023

Purpose: Describes the features of dosimetric planning for breast cancer and conducts statistics analysis of the radiation treatment planning results, while taking into account 2.5 years of work experience on the Halcyon linear accelerator at the Irkutsk Regional Cancer Center.

Materials and methods: Varian Halcyon tunnel type linear accelerator and Varian TrueBeam C-arm linear accelerator were used for breast irradiation. Treatment planning was performed in the Eclipse planning system, Acuros dose calculation algorithm. The experience of using the specified equipment and developments in the field of radiation treatment planning using the Halcyon system are presented.

Results: Developed an approach to planning breast radiation at the Halcyon linear accelerator. A retrospective analysis of 84 radiation treatment plans on linear accelerators of various types was carried out. Breast treatment plans for Halcyon linear accelerator have equal dosimetric parameters in comparison to the TrueBeam treatment plans.

Conclusion: Linear accelerator Halcyon can be used for treating breast cancer if staff understands specifics of treatment planning and treatment delivery.
Increasing to Accuracy Reductions Heterogeneous Dose Distribution to All-Out Volume of the Irradiation at Models Modified Weibull Distribution
Authors: Klepper L. Ia.
Published: February 2023

Purpose: To development of the methods of the estimation quality, systematized clinical information, which is described in the manner of probability of the arising the NTCP (complications in tissues) depending on volume of the irradiation and sharing the dose their uniform and heterogeneous irradiation.

Material and methods: Used designed mathematical models for calculation of NTCP and mathematical models, which allow to calculate reduction values of the identical doses of the uniform irradiation tissues equivalent on probability of the arising the beam complication to heterogeneous sharing the doses.

Results: Method of increasing to precision of the estimation to consensus systematized clinical information, founded on its presentation in the manner of differential histogram dose-volume, and on reductions heterogeneous doses distribution in identical dose all-out and uniform irradiation tissue.

Conclusion: It is shown that designed method of the estimation of the heterogeneous sharing the dose by way of his adduction to equivalent, on probability of the arising the beam complications in tissues, all-out irradiations tissues, allows to raise accuracy of the calculation of the identical dose of the source lumpy distribution tolerants doses. She allows to raise precision of the estimation to consensus systematized clinical values of tolerant doses, received of specialist.
Criteria for the Applicability of Computer Vision for Preventive Studies on the Example of Chest X-Ray and Fluorography
Authors: Arzamasov K. M. , Semenov S. S. , Kokina D. Yu. , Bobrovskaya T. M. , Pavlov N. A. , Kirpichev Y. S. , Andreychenko A. E. , Vladzymyrskyy A. V.
Published: February 2023

Purpose: In the conditions of a constant increase in the number of computer vision algorithms developed based on artificial intelligence (AI) for medical diagnostics, it becomes necessary to determine criteria for deciding whether their practical application for mass preventive studies of the population is appropriate.

Materials and methods: The study with the participation of several radiologists was conducted on a “Web platform for evaluating radiological studies” on a marked data set containing digital radiographs and fluorograms in an anterior direct projection. On the same data set, using the “Versioning Testing Platform”, responses were obtained from two commercial AI-based computer vision algorithms developed for the analysis of digital radiographs. Evaluation of the results obtained from doctors and algorithms (binary, in terms of “with pathology” and “without pathology”) was carried out using ROC analysis. For the threshold value calculated by the Yuden method, the following metrics were determined: sensitivity, specificity and accuracy.

Results: diagnostic accuracy metrics were calculated for the average assessment of radiologists and AI-based computer vision algorithms when searching for pathological changes on chest X-rays in anterior direct projection according to ROC analysis. The average values of diagnostic accuracy indicators of radiologists exceeded the indicators of AI services.

Conclusions: when deciding on the implementation of AI-based computer vision algorithms for preventive research, One should be guided by the metrics of diagnostic accuracy of a particular algorithm and use the average result of doctors in solving this diagnostic problem as the target values of metrics.
Examination of the Surface of Erythrocytes of Patients with Cervical Cancer by Immunofluorescence Analysis
Authors: Mamaeva S. N. , Alekseev V. A. , Kononova I. V. , Nikolaeva N. A. , Krylova T. A. , Pavlov A. N. , Gabysheva A. A. , Maksimov G. V.
Published: February 2023

The number of patients diagnosed with cervical cancer continues to increase all over the world. Despite the intensive development of diagnostic and therapy methods, the phenomenon of relapses in the absence of a clear explanation for their occurrence, and of metastasis are observed, which complicates treatment and affects the survival of patients. In this regard, there is a need to develop new research methods for a more detailed study of the occurrence and development of the disease at the molecular and cellular levels, as well as the effectiveness of treatment and the causes of relapses.

In this paper, nanoparticles are studied on the surface of red blood cells, which were revealed by the authors using scanning electron microscopy previously, and results of the study of blood samples of patients with cervical cancer using a new sample preparation method and immunofluorescence analysis for their identification are presented on the basis of the assumption that these nanoparticles are viral particles.

With the combination of immunofluorescence and electron microscopy methods, we were able to confirm our hypothesis of the viral nature of nanoparticles attached to the surface of red blood cells of patients diagnosed with cervical cancer. With this approach, it was found that the particles of human papillomavirus 16 and 18 are located on the cytoplasmic membrane of red blood cells. The results of this study indicate that viruses circulate in the patient's blood, and are attached to the surface of red blood cells. This apparently affects the development of cervical cancer, its relapse, and metastasis.
The Scanning Water Phantom Quality Assurance
Authors: Lebedeva Zh. S. , Granin D. D.I. , Medvedev P. A. , Pashkov O. V.
Published: February 2023

CONTENT

Introduction

Current recommendations

Positioning the detector and phantom

Detectors and electronics

Scanned dosimetry data acquisition

Output

Comparison of commercially available phantoms

Conclusion
Uma revisão integrativa sobre a importância da educação financeira considerando os reflexos da pandemia de covid-19
Authors: Borges de Carvalho Josimauro , De Souza Pereira Andreza
Published: February 2023

Diante do cenário da pandemia da Covid-19 a partir do ano de 2020, cujos reflexos ainda podem ser sentidos, percebe-se uma necessidade cada vez mais latente de se ofertar uma educação financeira de qualidade para aqueles jovens que estão em um contato secundário com sua vida financeira. O objetivo deste estudo foi compreender a importância de se ofertar Educação Financeira para os jovens no contexto da Covid-19. Trata-se de uma pesquisa bibliográfica realizada por meio da busca de artigos científicos nas bases Google Acadêmico e Scielo, de estudos publicados nos anos de 2020 a 2021. Os resultados obtidos indicam que o nível de endividamento do brasileiro se elevou do período em que a economia foi impactada negativamente em decorrência da pandemia de Covid-19 e, diante desse cenário, a educação financeira mostra-se indispensável principalmente para os jovens, quem possuem pouca experiência com o uso de recursos financeiros.
ANALISIS PENERAPAN SISTEM INFORMASI APLIKASI PEGADAIAN DIGITAL SERVICE DALAM MEMUDAHKAN NASABAH BERTRANSAKSI (STUDI KASUS PEGADAIAN UNIT BETUN)
Authors: Fachruzi Andi Syahril
Published: February 2023

The PDS (Pegadaian Digital Service) application is an innovation and new breakthrough by PT. Pegadaian (Persero). The Betun Unit Pawnshop Office is currently in the process of socializing the PDS Application to all pawnshop office customers. The features in the PDS Application apart from offering a gold savings feature, Pegadaian Digital also offers online pawning features, installment/billing information, maturity information, and several other interesting features. This feature offers several advantages to users. As a new application for customers, of course it will take time for the acceptance process in terms of features and usability. Even the employees of PT. Pegadaian (Persero) has the right to assess and evaluate the content offered on the application. Making this application aims to make it easier for customers and prospective customers to interact indirectly with Pegadaian, namely by knowing the up-to-date gold price, checking bills, making payments, and others. With the Digital Pegadaian application, customers no longer need to come to the outlet to make payments, they only need to go through the application and then pay according to the bank that has been determined by Pegadaian or through ATM, SMS Banking, and M-Banking. The purpose of this study is to evaluate the PDS (Pegadaian Digital Service) application in terms of usability using the Website Usability Evaluation (WEBUSE) method and create a table of recommended solutions from a list of usability problems. The WEBUSE method is used as a tool to measure the usability level of the PDS (Pegadaian Digital Service) application based on the perception of the end user (in this case the management of PT. Pegadaian and its customers). Data collection is done by distributing questionnaires to all employees and customers who come to make transactions or in the process of the PDS Application socialization agenda. The results of this study are expected to be input for the Management of PT. Pegadaian, especially the Betun Unit Pawnshop Office in an effort to implement the Digital Service Pawnshop Application.
Evaluasi Portal Berita Daring Polda Nusa Tenggara Timur
Authors: Balla Maria Selywati
Published: February 2023

Tribratanews merupakan portal berita Kepolisian Negara Republik Indonesia (Polri) dengan jaringan informasi fungsi humas di seluruh satuan wilayah jajaran Polri, termasuk di dalamnya yakni portal berita Tribratanewsntt.com. Menjamurnya portal berita daring belakangan ini bukan berarti bahwa segala akses untuk kebutuhan informasi dari pengguna dapat terpenuhi. Karena banyak pula di antara portal tersebut  tidak  dapat  memenuhi  tujuan  awal  kenapa  portal  tersebut  dibuat  dan  bahkan  banyak  yang mengecewakan pengguna yang mengaksesnya. Permasalahan yang sering ditemui yakni banyaknya portal berita daring yang tidak memperhatikan masalah kekayaan media dan juga kegunaannya (usability), sehingga tidak sedikit pengguna portal berita tersebut memperoleh informasi yang kurang akurat dan terbaru, mengalami kebingungan, kejenuhan, bahkan tersesat dengan tampilan yang tidak sesuai. Sebagai sebuah portal berita daring, Tribratanewsntt.com perlu dievaluasi untuk mengetahui apakah portal tersebut telah mampu mencapai tujuan awalnya yakni sebagai media informasi Polda NTT. Evaluasi terhadap portal berita daring Tribratanewsntt.com penting dilakukan mengingat persaingan yang terjadi. Penelitian ini bertujuan untuk mengevaluasi portal berita Tribratanewsntt.com dari segi kekayaannya sebagai sebuah media informasi dengan menerapkan Media Richness Theory (MRT) dan juga dari segi kegunaannya dengan menggunakan System Usability Scale (SUS). Hasil evaluasi kegunaan memperoleh skor SUS sebesar 82,425 dengan tingkat penerimaan termasuk kategori “acceptable”, tingkat skala kegunaan termasuk kategori “B”, dan adjective rating termasuk kategori “excellent”. Hal tersebut berarti Tribratanewsntt.com dapat digunakan untuk membantu mencapai tujuan dari para responden untuk memperoleh informasi dengan cukup memuaskan dan tanpa membutuhkan sumber daya dalam jumlah yang besar. Sedangkan hasil analisis kekayaan media berdasarkan 8 (delapan) unsur Media Richness Theory (MRT) menunjukkan bahwa portal berita daring tersebut belum sepenuhnya memenuhi indikator-indikator pada setiap unsur MRT, sehingga Tribratanewsntt.com belum sepenuhnya menjadi media yang “kaya”
Prevalence and molecular identification of Plasmodium falciparum
Authors: Boush Mohammed A , Djibrine Moussa A. , Saeed Abdalla A , Mussa Ali , A Maki , Hajisa Khalid
Published: February 2023

Background: Malaria is one of the most important infectious diseases in tropical and subtropical regions, and 45% of the population living in areas that suffer from stable malaria transmission in Sudan. The prevalence of symptomatic Plasmodium infection based on microscopy and RDTs is poorly documented in Nyala city. This study was conducted to determine the prevalence of plasmodium infection and molecular identification of plasmodium species in Nyala city, Sudan.

Methods: A cross-sectional study was conducted from July 2018 to December 2018 to determine the prevalence of malaria and molecular identification of plasmodium species in Nyala city, Sudan. A total of 300 suspected patients were enrolled in this study. Microscopy and RDTs were performed to estimate the prevalence and nPCR to detect the plasmodium genus and species.

Results: Of 300 patients, 113 (37.7%) were positive for malaria. Plasmodium falciparum was the only prevalent species detected amongst the study population. The prevalence of plasmodium infection by microscopy and RDTs was 113 (37.7 %) and 106 (35.3 %), respectively. While PCR result showed prevalence of 47 (47%).

Conclusions: This study showed that the only prevalent species identified was P. falciparum, the findings demonstrate no existence of non-falciparum malaria, and children less than five years old were the most infected patients. The diagnostic performance of microscopy was better than RDTs in the diagnosis of malaria infection.
Modeling how fast teacher trainees master statistical concepts in verification of the learning curve theories
Authors: Richard Ayamah  , Adolf Odei  , Patrick Kwame Babah  , Emmanuel Teku
Published: February 2023

This study was undertaken to model and evaluate how fast Ghanaian teacher trainees master statistical concepts, in verification of the learning curve theory. The target population was all the 2020/2021 academic year level 300 teacher trainees in Ghana. However, St. Joseph’s College of Education (JOSCO), Bechem, was selected out of proximity from the 46 colleges of education in Ghana. At JOSCO, the Science/Mathematics, Agriculture/ICT and the Social Studies classes were randomly selected from the five level 300 classes and all the students in the three classes served as the experimental units. In effect, a ten-week period experimental tuition and evaluation on Educational Statistics was conducted and the data on the percentage of statistical concepts mastered by the teacher trainees were collected for the study. Tabular and graphical analyses on the data were carried out for the verification of the learning curve theory. Ordinary differential equations were used to derive the model for the prediction of the percentage of statistical concepts mastered by the teacher trainees. Graphical and numerical residual analyses were also conducted for the model adequacy checking. In all, the learning curve was successfully verified and the derived model was also found to be adequate for the prediction of the percentage of statistical concepts mastered by the teacher trainees at any point in time. This happens to be the first time research has been successfully conducted to verify the learning curve theory in statistical concept build-up in the colleges of education in Ghana.
EVALUASI UNJUK KERJA POMPA SENTRIFUGAL CDX 200/20 DI CAVITATION DEMONSTRATION UNIT PEM AKAMIGAS
Authors: Harfy Kamikho , Handoko Susilo
Published: February 2023

Evaluasi unjuk kerja merupakan penilaian yang dilakukan dengan mengamati kegiatan dari peralatan dalam melakukan suatu pekerjaan. Tujuan dari evaluasi unjuk kerja adalah untuk mengetahui sejauh apa peralatan tersebut dapat melakukan tugasnya. Evaluasi unjuk kerja pompa sentrifugal akan dilakukan dengan menganalisa kurva operasi dari pompa tersebut. Kurva pompa sentrifugal ini akan dibuat berdasarkan data operasi, pertama dengan metode variable speed dan kedua dengan variable valve. Dari metode itu akan didapat nilai kapasitas (Q) dan tekanan fluida pada valve discharge. Data tekanan valve discharge dapat diubah menjadi nilai head pompa. Nilai head system dan kapasitas digunakan untuk membuat kurva head-kapasitas (H-Q). Kurva head-kapasitas akan disilangkan dengan kurva head  pompa dari manufacture dan didapat titik operasi pompa pada sistem. Titik operasi tersebut digunakan untuk mengetahui nilai efisiensi terkini dari pompa. Titik operasi pompa yang didapat adalah pada head 30m dan kapasitas 115 l/min maka nilai effisiensi pompa saat ini adalah 45 persen. Nilai effisiensi pompa telah turun sebanyak 11.6 persen yang awalnya bernilai 56.6 persen.
OPTIMASI KEBUTUHAN UDARA PEMBAKARAN BATUBARA UNTUK MENINGKATKAN KINERJA BOILER PLTU TANJUNG AWAR AWAR
Authors: Alfarisyi Muhammad , Dharmawan Aditya , Miswar Danang Yudi
Published: February 2023

PLTU adalah salah satu jasa pembangkit untuk transmisi listrik nasional. Agar dapat menghasilkan pasokan listrik yang optimal PLTU umumnya terdiri dari beberapa unit. PLTU Tanjung Awar-awar masih memanfaatkan batubara sebagai bahan bakar utama karena harga batubara yang relative lebih murah dibandingkan jenis bahan bakar lainnya. Boiler PLTU merupakan alat utama yang harus dijaga dan handal dalam menjamin produksi steam sehingga dapat menghasilkan energi listrik dari induk generator. Efisiensi boiler merupakan gambaran kehandalan kinerja boiler. Faktor-faktor yang mempengaruhi efisiensi boiler diantaranya yaitu excess air, flow air umpan, suhu awal air umpan, suhu udara bakar, spesifikasi batubara yang digunakan, dan umur dari alat boiler itu sendiri. Pengaturan jumlah udara pembakaran batu bara dan Excess Air dapat meningkatkan efisiensi boiler dengan mengurangi jumlah losses yang terbawa oleh sisa-sisa pembakaran batubara. Metode yang digunakan adalah metode heat los, dari hasil pengamatan yang dilakukan didapatkan efisiensi normal Boiler PLTU sebesar 82,07 persen dan dapat dioptimalkan menjadi 82,86 persen.
Analisis Penentuan Kebutuhan Suku Cadang Refueller di DPPU XYZ
Authors: Adelia Annisa Safira , Sutanto Agus
Published: February 2023

DPPU XYZ menggunakan refueller untuk menyalurkan Avtur ke konsumen. Terdapat salah satu refueller yang berhenti beroperasi selama beberapa bulan dikarenakan suku cadang refueller yang rusak tidak tersedia di gudang dan perbaikan harus menunggu sampai suku cadang tersedia. Ketidaktersediaan suku cadang akan berdampak pada pemanfaatan kinerja yang kurang maksimal dan dapat menghambat penyaluran Avtur. Reliability Centered Spares digunakan untuk mengetahui jumlah suku cadang kritis yang dibutuhkan dalam jangka waktu tertentu. Metode ini dihitung berdasarkan data kerusakan suatu komponen yang kemudian dijumlahkan menjadi Mean Time To Repair dan Mean Time Between Failure komponen.  Metode poisson process digunakan untuk mengetahui hasil akhir dari persediaan suku cadang. Dengan menggunakan metode Reliability Centered Spares, dapat diketahui bahwa untuk memenuhi kebutuhan suku cadang kritis dari 8 refueller yaitu filter solar atas sebanyak 46 komponen, filter solar bawah sebanyak 56 komponen, filter oli sebanyak 30 komponen, dan filter udara sebanyak 30 komponen.
OPTIMALISASI UNJUK KERJA HIGH PRESSURE WATER HEATER 8B DI PT PAITON OPERATION AND MAINTENANCE INDONESIA UNIT 7 PLTU PAITON
Authors: Prasetyo Alfath Rizky , Hilman Ayende
Published: February 2023

High Pressure Water Heater 8A yang terdapat di PT. Paiton Operation and Maintenance Indonesia (PT. POMI) merupakan jenis alat penukar panas atau heat exchanger untuk pemanas air umpan yang nantinya akan melewati economizer dan menuju masuk ke dalam boiler. Pada high pressure heater ini menggunakan media pemanas hasil ekstraksi steam dari high pressure turbine. High pressure heater yang terdapat pada PT. POMI ini memiliki ukuran diameter dalam shell sebesar 60 in dan di dalamnya terdapat 1428 tube yang berukuran 5/8 in. Setelah dilakukan analisis perhitungan tentang efektivitas unjuk kerja pada alat ini diketahui memiliki nilai efektivitas sebesar 87,26 % dan memiliki faktor pengotoran atau fouling factor sebesar 0,00527. Setelah itu dilakukan optimalisasi supaya nilai efektivitas dapat meningkat dan nilai fouling factor dapat dibawah dari batas maksimalnya, yaitu 0,001 dengan cara melakukan percobaan dengan mengubah besaran suhu keluar pada sisi shell dan suhu keluar pada sisi tube. Sehingga didapatkan kenaikan nilai efektivitas 2,76% menjadi 90,02% dan juga didapatkan nilai fouling factor yang lebih kecil sebesar 0,000002816.
EVALUASI UNJUK KERJA GAS ENGINE 11 WARTSILA W2034SG DI PT PJB UBJOM PLTMG ARUN
Authors: Chalis Aksanul , Novianto Hernawan
Published: February 2023

PJB UBJOM PLTMG ARUN adalah pembangkit listrik tenaga mesin gas yang berada Paloh Muara Satu Kota Lhokseumawe. Salah satu Gas Engine yang dimiliki PT. PJB UBJOM PLTMG ARUN adalah Gas Engine 11 type Wartsila W2034SG yang menghasilkan listrik 9,7 MW. Akan tetapi saat ini hanya beroperasi 6,5 MW menyesuaikan dengan permintaan PLN, saat ini konsumsi bahan bakar engine mengalami ketidakwajaran. Sehingga dilakukanlah evaluasi terhadap unjuk kerjanya. Metode yang digunakan adalah dengan melakukan perhitungan menggunakan persamaan yang ada, dan setelah dilakukan perhitungan maka diketahui efisiensi thermalnya mengalami penurunan, dari yang semula 47 persen menjadi 44,2 persen.
ANALISIS KETAHANAN STOCK PRODUK AVTUR DI DPPU XYZ
Authors: Akerina Lesman Jehozah Cristophorus , Sutanto Agus
Published: February 2023

DPPU XYZ merupakan salah satu DPPU yang bertugas melayani serta memastikanketersedian stock Avtur dalam kondisi aman. Dengan adanya jumlah kedatangan pesawatyang semakin meningkat secara tidak langsung pula bisa mempengaruhi permintaan Avturyang berdampak pada ketahanan stock tangki. Dalam menjaga ketahanan stock tangki diDPPU XYZ dilakukan peramalan untuk dua tahun kedepan agar ketahanan stock Avtur tetapterjaga. Oleh karena itu dilakukan peramalan Thruput Avtur dengan menggunakan metodeWinter Eksponential Smoothing untuk mengatasi adanya pola trend dan juga seasonalsehingga Thruput Avtur dapat diramal dengan nilai error yang kecil. Hasil peramalanThruput Avtur untuk dua tahun kedepan mengalami presentase kenaikan sebesar 21 persen daridata dua tahun sebelumnya. Dikarenakan peramalan yang dilakukan mendapatkan hasilyang naik dibandingkan tahun-tahun sebelumnya, maka berdampak dapa KSTT yangmenurun yaitu sebesar 13 hari.
Analisis Quantity Pada Proses Produksi Pelumas di PT PQ Dengan Metode EOQ
Authors: Djabumir Calvin , Venriza Oksil
Published: February 2023

Persediaan merupakan suatu aktiva yang meliputi barang-barang milik perusahaan dengan maksud untuk dijual dalam suatu periode usaha tertentu atau persediaan barang-barang yang masih dalam pengerjaan atau proses produksi ataupun persediaan bahan baku yang menunggu penggunaannya dalam proses. Suatu perusahaan mempunyai tujuan untuk mendapatkan keuntungan yang optimal. Keuntungan yang optimal dapat diperoleh jika perusahaan mampu menjalankan manajemen perusahaan dengan baik. artinya perusahaan harus mampu mengantisipasi keadaan maupun tantangan yang ada dalam manajemen persediaan untuk mencapai sasaran akhir, yaitu untuk meminimalisasi total biaya yang harus dikeluarkan oleh perusahaan untuk penanganan persediaan. PT PQ merupakan perusahaan manufaktur produk minyak pelumas untuk kendaraan motor, mobil, dan industri. Sehinggga tujuan dari analisisis ini adalah untuk mengetahui pengendalian persediaan material packaging fast moving yang dilakukan oleh PT PQ dan untuk mengetahui jumlah pesanan dan biaya persediaan material packaging fast moving type lithos 0.8 L pada PT PQ dengan metode EOQ (Economic Order Quantity). Berdasarkan perhitungan dengan mengunakan metode Ecomic Order Quantity (EOQ) , didapatkan ukuran pemesanan ekonomis pada material packaging fast moving type lithos Yamlube 0.8 L yaitu 179.670,46 unit dan titik pemesanan kembali pada posisi persediaan di gudang mencapai 548.360,9 unit. Dan adanya penghematan biaya persediaan sebesar 85 persen jika pemesanan dilakukan menggunakan metode EOQ.