bluuebunny/crossref_metadata_2025 huggingface dataset:
A STUDY OF MOBILE BANKING SERVICES BY STATE BANK OF INDIA
Authors:   School of Business   Galgotias University, Pushong Swapnil Mark
Published: May 2024

This report aims to conduct an amazing insight into SBI's mobile services. For this purpose, we will try to comprehensively assess their efficacy, customer satisfaction levels, and areas that need further improvement. Stepped up in the digital banking skyline, with the usage of mobile phones surging as a means of banking transactions, understanding the intricacies of SBI's mobile services is critical in terms of keeping up the competition and for the purpose of customers' benefit. Studies' goals are based on mobile banking adoption factors' research, usage patterns' discovery and customers' perceptions' investigation. The research approach of mixed-method is applied, where quantitative information is collected through surveys administered to SBI's customers, while qualitative data is fully exhausted within the interviews and focus group discussions. This technique offers possibilities to quantitative metrics as qualitative feedback analysis and therefore enables a complete overview of the subject matter. The key findings from the study illuminates the magnitudes and deficits of mobile services provided by SBI, and suggests agent of success as well as areas for improvement. With detailed data analysis the research pinpoints the things influencing customers’ contentment and immersion with SBI’s mobile services, as well as the factors holding back adoption and usage. This information is significant for the later development of reasonable conclusions and relevant prescriptions for SBI's mobile banking strategy. Finally, on the basis of research results, recommendations are forwarded to SBI as the mobile services are to be improved, simple and usable solutions are to be created, and customer pain points are to be eliminated. Realizing the recommendations, SBI would stay in top of digital banking landscape by increasing customer satisfaction and loyalty. It would continue to be relevant in the era where customers are becoming more mobile-centric in their banking.
Analysis of IDBI Federal Life Insurance's Financial Performance and Statements in NCR: An In-Depth Review
Authors:   SCHOOL OF BUSINESS GALGOTIAS UNIVERSITY, ALAM ANAS
Published: May 2024

The research paper delves into the financial statement analysis of IDBI Federal Life Insurance, aiming to conduct a thorough examination of its financial standing. It will encompass an extensive review of the company's financial statements, key ratios, capital structure, profitability, liquidity, and solvency. Moreover, the study will compare the company's financial performance with that of its peers in the life insurance sector to pinpoint strengths and weaknesses. Recommendations for improvement will be proposed based on these findings. Additionally, the research will evaluate the influence of external factors like economic conditions, regulatory changes, and market trends on the company's financial performance. The methodology involves collecting and analyzing financial data, performing ratio analysis, and drawing conclusions to provide actionable insights. Ultimately, the research aims to offer valuable insights into IDBI Federal Life Insurance's financial health and performance, guiding strategies for sustainable growth and success.
In-Depth Financial Statement Review of IDBI Federal Life Insurance in New Delhi: A Comprehensive Analysis
Authors:   SCHOOL OF BUSINESS GALGOTIAS UNIVERSITY, KAMAAL MOHD
Published: May 2024

The research paper delves into the financial statement analysis of IDBI Federal Life Insurance, aiming to conduct a thorough examination of its financial standing. It will encompass an extensive review of the company's financial statements, key ratios, capital structure, profitability, liquidity, and solvency. Moreover, the study will compare the company's financial performance with that of its peers in the life insurance sector to pinpoint strengths and weaknesses. Recommendations for improvement will be proposed based on these findings. Additionally, the research will evaluate the influence of external factors like economic conditions, regulatory changes, and market trends on the company's financial performance. The methodology involves collecting and analyzing financial data, performing ratio analysis, and drawing conclusions to provide actionable insights. Ultimately, the research aims to offer valuable insights into IDBI Federal Life Insurance's financial health and performance, guiding strategies for sustainable growth and success.
“STUDY OF ICICI E- RECRUITMENT”
Authors:   Galgotias University, AGARWAL Dr. SHIVANI
Published: May 2024

The term e-Recruitment means the process of finding and hiring the best-qualified candidate (from within or outside of an organization) for a job opening, in a timely and cost effective manner (Bhupendra & Swati, 2015). The recruitment process includes activities like analysing job requirements, attracting candidates, screening applicants, hiring and welcoming the new employee to the organization. E- Recruitment is the practice of using web-based resources for tasks involved with searching, attracting, assessing, interviewing and hiring new employees. Armstrong (2009) defines e- Recruitment as a process that uses the internet to advertise or post vacancies, provide information about the jobs and the organization and enable e-mail communication to take place between employers and candidates. The function of e- Recruitment is to make the processes more productive as well as less expensive. Online recruitment can attract a larger pool of potential employees and smoothens the selection process.
Navigating the Dynamics of Mutual Funds: An Insight into Investor Behavior
Authors:   Galgotias University, Shahi Rudra
Published: May 2024

This paper delves into the intricate landscape of mutual funds by exploring the underlying dynamics of investor behavior. Through a comprehensive analysis, it sheds light on the various factors that influence investors' decision-making processes, including risk tolerance, investment goals, and market conditions. The study highlights the importance of understanding these dynamics in order to navigate the complexities of mutual fund investments effectively. By examining real-world scenarios and empirical data, valuable insights are gleaned into how investors respond to different market conditions and how their behavior impacts fund performance. Additionally, the research delves into the psychological aspects that drive investor behavior, such as cognitive biases and herd mentality, providing a deeper understanding of why investors make certain choices. Ultimately, this study offers a nuanced perspective on the intricacies of mutual fund investing and provides guidance on how investors can navigate these dynamics to make informed decisions. Keywords: mutual funds, investor behavior, risk tolerance, investment goals, market conditions, cognitive biases, herd mentality, fund performance, decision-making processes, empirical data, psychological aspects.
A STUDY ON SAVINGS AND INVESTMENT: RISK AND OPPORTUNITIES
Authors:   SCHOOL OF BUSINESS GALGOTIAS UNIVERSITY GREATER NOIDA, MAGHFOOR SUBOOR
Published: May 2024

This study investigates the intricate relationship between savings, investment, risk, and opportunities in contemporary financial landscapes. With financial markets becoming increasingly complex and interconnected, understanding the dynamics of savings and investment has become paramount for individuals, businesses, and policymakers alike. The first part of the study delves into the concept of savings, examining the various motivations behind saving behavior and the factors influencing individuals' decisions to save. It explores traditional saving instruments such as savings accounts, as well as newer forms such as robo-advisors and digital wallets, highlighting the evolving nature of saving practices in the digital age. Moving on to investment, the study elucidates the diverse array of investment vehicles available to investors, ranging from stocks and bonds to real estate and alternative assets. It analyzes the risk-return tradeoff inherent in different investment options and discusses strategies for constructing well-diversified investment portfolios tailored to investors' risk preferences and financial goals. Finally, the study identifies emerging opportunities in the savings and investment landscape, including technological innovations such as blockchain technology and peer-to- peer lending platforms, which are reshaping traditional financial systems and offering new avenues for wealth accumulation and capital deployment. By synthesizing theoretical insights with empirical evidence, this study provides valuable insights into the complex interplay between savings, investment, risk, and opportunities, offering practical recommendations for individuals
Fast Finance and the Political Economy of Catastrophic Dam Collapse in Lao PDR: The Case of Xe Pian-Xe Namnoy
Authors: Souvannaseng Pon
Published: May 2024

In the dark of a July night in 2018, a 5-billion-cubic-metre torrent of muddy water crashed through rooftops and ripped through the downstream villages of southeast Lao People's Democratic Republic (Lao PDR). An auxiliary "saddle" dam had collapsed in the US$1.02 billion Xe Pian-Xe
Namnoy (XPXN) Hydropower Project that was still under construction and had just reached financial contractual close five years prior, in 2013. In the aftermath of the collapse, official state narratives pointed to extreme weather conditions and "unforeseen" construction and engineering miscalculations,
viewing soil conditions as the primary culprit. This paper examines the financial dimensions of dam failure and introduces the term "fast finance": financier-driven timelines that have drastically expedited and shortened the legal, social, and pre-construction processes involved in hydropower
dam projects to the detriment of dam safety, due diligence, and local participatory input. Extreme weather and anthropogenic climate change are not sole explanatory factors in the XPXN dam disaster. This paper highlights the also significant role of financial and political interests as contributing
factors in dam safety and failure alongside extreme weather. The paper challenges conventional "natural disaster" framing of dam collapse by bringing into focus ex-ante political decision-making, financial engineering, and construction planning prior to dam construction to highlight the ways
in which the XPXN catastrophe also had anthropogenic and "unnatural" contributing factors. Fast finance encompasses the role of temporality and the responsibility of state-business actors in ex-ante financial and infrastructure decisions that conclude with catastrophic outcomes. The article
examines the re-engineering of contemporary dam finance through a case study of Lao PDR and argues that issues of financial engineering should be examined alongside other forms of civil, mechanical, structural, and hydrological engineering in the analysis of dam disasters. The temporal logics
of financial actors—particularly the financialized logic of fast finance—has displaced the public-good-producing logic of patient capital. Financial logics shape and condition other forms of engineering and construction and are central to considerations of dam safety and accountability.
Naturalizing discourses around extreme weather and aging dams deflect from the financial decisions and policy action, or inaction, of state-business actors to prevent dam collapse.
Explication of Ogba Proverbs as a Tool for Conflict Resolution
Authors: Ohia Dr. Ben-Fred
Published: May 2024

Proverbs originated orally based on the oral literature history of storytelling passed down from generation to generation through stories and sayings. However, some believed that they originated from written scripts. Proverbs are words of wisdom used to impart knowledge to people. In Ogba, proverbs are used predominantly by the elders to warn, advice, instruct and educate on issues of paramount importance to the society. Proverbs elu are epigrammatic in nature and usually misunderstood as idiom olu-eknurnu. Proverbs elu often use figures of speech, such as metaphors, similes or allusions to make a point. In the literary parlance, renowned African writers like Chinua Achebe, Ngugi Wa Thiong’o, Amos Tutuola, Wole Soyinka, Ola Rotimi and others adopt the use of proverbs in their works. This paper analyses the Ogba proverbs as a tool for conflict resolution in Ogba land of Rivers State, Nigeria. It is discovered that proverbs are used in major types of discourse involving the elders as evidenced in their use in palaces of chiefs to settle issues of marriage, land, chieftaincy, accusations of witchcraft and wizardry and other cases that are settled locally according to Ogba tradition and custom. This paper adopts the qualitative approach propounded by Isidore Okpewho. It concludes that proverbs are a veritable tool used by the elders to settle disputes in their homes, families and kindred.
Verantwoordingsonderzoek 2020
Authors: de Smit Ruud , Borg Robin
Published: May 2024

Verantwoordingsonderzoek 2020

In de rubriek Beleidsonderzoek Benut besteden we dit keer aandacht aan het onderzoek naar de mate waarin fiscale regelingen voldoen aan het toetsingskader uit de Rijksbegrotingsvoorschriften.
Youth Sparks via 4-H: Relations with Program Quality, Dosage, and
Involvement
Authors: Skrocki Alexandra , Ellis Gary , Ettekal Andrea , Locke Darlene
Published: May 2024

Using a statewide sample of participants in 4-H programs,
we tested associations among youth sparks, program quality, program dosage, and four
types of involvement (breadth of participation in out-of-school-time beyond 4-H, scope
of learning strategies, degree of specialization, and cumulative program immersion).
Participants were 180 Texas 4-H alumni who graduated from high school in 2013 and 2014
and had two or more years of involvement in Texas 4-H programs. Data were collected via
an electronic questionnaire based on a database of former Texas 4-H members. Twelve
hypotheses were tested, linking program quality to sparks through indirect and direct
relations. Eleven of the twelve hypotheses were supported. Program quality had a strong
direct relation to sparks (b = .41). Direct relations between sparks and the facets of
immersion were also found (b = .31 for the degree of specialization in one of Texas
4-H’s program areas and b = .27 for cumulative program immersion). Indirect associations
were also significant. Dosage (years in Texas 4-H) was not significantly related to
sparks.
Exploring the Use of Trauma-Informed Care Practices in Extension
Authors: O'Brien Caitlin , Gillen Martie
Published: May 2024

A content analysis of 63 land-grant Extension university
websites was conducted to examine the promotion of trauma-informed care (TIC) through
the sharing of resources, providing instructive webinars and/or in-person events, and
offering comprehensive programs. While many Extension universities are sharing
resources, only nine universities (14%) featured robust TIC Extension programs, and 40%
shared no TIC information. Additionally, we found no indication of internal education
programs across the universities on adverse childhood experiences (ACEs) and TIC
practices for Extension faculty and staff. These findings highlight opportunities to
increase efforts with the public as well as internally within Extension.
A Mindful and Sustainable Eating Intervention to Improve Attitudes
Related to Mindfulness, Sustainability, and Fruit and Vegetable Consumption in
Elementary Schools
Authors: Schachtner-Appel Amy , Song Heejung
Published: May 2024

Excessive plate waste is generated in elementary school
cafeterias. Adapting nutrition promotion strategies to target waste reduction and
encouraging mindful and sustainable eating (MSE) are possible strategies to encourage
students to reduce waste during school lunch. Farm to Tray, Tray to Farm is a 16-week
intervention that aims to encourage elementary school students to develop mindful and
sustainable eating behaviors. An educational curriculum was delivered to eight 5th-grade
students, who served as peer leaders and disseminated messages throughout the school.
Additional strategies included cafeteria reinforcements and opportunities for food
recovery. A pilot test of the program was conducted in two schools using a
quasi-experimental design. A pre/post survey was administered to 3rd–5th-grade students
to measure changes in MSE behaviors, and analyses were conducted using the test of
marginal homogeneity and t-test for independent samples to evaluate within- and
between-group differences, respectively. In total, 169 students (n = 102 intervention
and n = 67 comparison) completed both surveys. From baseline to follow-up, intervention
students reported significantly increased self-efficacy to base lunch choices on body
cues. A higher proportion of intervention than comparison students increased ratings
regarding behavioral strategies to practice MSE and expectations of benefits from MSE.
Advancing Pharmaceuticals with Machine Learning: A Short Review of Research and Development Applications
Authors: Khalid Wajeeha , Khalid Muhammad Yahya , Hena Madiha , Sarwar Atif , Iqbal Shahzaib
Published: May 2024

In recent years, the field of pharmaceutical research and development (RD) has seen a surge of interest in artificial intelligence (AI) and machine learning (ML) technologies. These advancements may transform the industry by addressing challenges related to data analysis, computational capabilities, and rising costs associated with drug development. ML techniques have been progressively refined and applied to various stages of drug discovery over the past 15–20 years. Notably, there is a growing focus on utilizing ML in clinical trial design, conduct, and analysis, which the COVID-19 pandemic and the increased reliance on digital technology in clinical trials have further accentuated. However, it is crucial to move beyond mere buzzwords and acknowledge that the scientific method remains essential for drawing meaningful insights from data. By doing so, we can distinguish between genuine advancements and exaggerated claims, leading to informed decision-making regarding the optimal integration of ML methods in drug development. This review aims to provide a comprehensive understanding of key concepts, understand real-world usage, and offer a balanced perspective on the effective utilization of ML in RD.
Applications of Natural Polymers in Regenerative Medicine and Tissue Engineering
Authors: Shabbir Ali Abdallah , Gul Rabia , Usman Halima , Naseer Faiza
Published: May 2024

Natural polymers, or biopolymers, are widely utilized in regenerative medicine and tissue engineering. These polymers, derived from proteins, polysaccharides, and nucleic acids, serve as biomaterials for scaffolds, drug delivery systems, and bioactive materials that mimic the extracellular matrix. They offer advantages such as biocompatibility, biodegradability, versatility, and integration with gene therapy. Collagen, gelatin, chitosan, hyaluronic acid, fibrin, and alginate are commonly used natural polymers in regenerative medicine. They promote cell growth, tissue formation, wound healing, and tissue regeneration. Natural polymers also play a crucial role in controlled drug and gene delivery systems, providing safe and effective alternatives to synthetic polymers. Moreover, they contribute to developing bioactive and bio-functional materials, including hydrogels, which mimic natural biological processes and have applications in tissue engineering, drug delivery, and wound healing. Overall, natural polymers hold great promise for advancing regenerative medicine and tissue engineering. However, several challenges impede the widespread adoption and utilization of natural polymers in regenerative medicine. These challenges include variations in batch-to-batch composition, limited mechanical strength, rapid degradation rates, immunogenicity concerns, and difficulties achieving precise control over their properties. Overcoming these challenges necessitates a comprehensive understanding of the structure-function relationships of natural polymers and the development of innovative processing techniques to enhance their mechanical properties and stability. The future of natural polymers in regenerative medicine holds immense potential. Ongoing research efforts focus on refining their properties, tailoring their degradation rates, and integrating them with advanced technologies like 3D bioprinting and nanotechnology. By leveraging these advancements, natural polymers can be further optimized for specific tissue engineering applications, enabling the creation of patient-specific scaffolds, enhanced wound healing materials, and personalized drug delivery systems. Additionally, harnessing the innate bioactivity of natural polymers and their interactions with cells and tissues opens new avenues for the development of bioactive materials that promote tissue regeneration and healing.
A Review of the Genetic Variants Affecting Efficacy and Adverse Effects of Standard of Care Treatment in Patients with Chronic Myelogenous Leukemia
Authors: Ullah Aman , Ali Fawad , Muhammad Syed Aun` , Hassan Syed Shams Ul
Published: May 2024

Chronic myelogenous leukemia (also called CML or chronic granulocytic leukemia) is a disorder in which the bone marrow generates many white blood cells. There is no recognized etiology for CML in most individuals. Only a few known risk factors for CML development have been identified related to exposure to specific chemicals. It is distinguished by a cytogenetical irregularity comprising a reciprocal translocation between the long arms of chromosomes 22 and 9 [t (9;22)]. CML treatment entails taking a variety of drugs and undertaking additional therapies, all of which can cause unpleasant side effects. In this manuscript, we have sifted through the literature and compiled studies investigating various gene variants affecting the efficacy and adverse effects of the standard of care treatment in CML. Our study shows some promising candidate genes that may be used as a predictor of certain adverse effects of CML treatment. Recommendations are made to employ these genetic variants in clinical medicine.
Editor's Summaries of the Articles Published in This Issue of Precision Medicine Communications
Authors: Editorial Staff
Published: May 2024

In this issue, Anum and colleagues have reported evidence-based prioritization and scoring of genomic loci interacting with pioglitazone therapeutic response in diabetic patients; Hasan and colleagues designed a study to determine the association of CP2C19*2 loss of function polymorphism with acute coronary syndrome patients receiving Clopidogrel, Zaheer, et al., reviewed escitalopram use in depression & the influence of genetic variations on its safety & efficacy,  Ahmed and colleagues reviewed and discussed single nucleotide polymorphisms associated with the safety and efficacy of anti-gout medications, while Haroon et al., compiled, reviewed and discussed the studies showing the genetic influence on Losartan's antihypertensive and uricosuric actions.
Exploring the Potential of Drug Repurposing: Detection of Cystic Fibrosis Transmembrane Conductance Regulator as a Biomarker in Breast Cancer Patients
Authors: Rafiq Sobia , Khan Sana , Wazir Shumaila , Nawaz Haseena , Khan Mah Muneer , Fatima Sadia , Jamal Babar , Ali Asif , Khan Ishaq N
Published: May 2024

Despite the advancements in cancer treatment and the benefits of personalized medicine, breast cancer (BC) remains a significant health concern. Moreover, conventional treatment options are costly and often associated with severe side effects, highlighting the need to identify new biomarkers and innovative treatment strategies for BC. Drug repurposing presents an approach that expands the therapeutic window further to mitigate the financial burden and minimize the potential harm caused by existing anticancer drugs. In the present study, we aim to suggest noncancerous FDA-approved drugs for repurposing, through molecular docking studies in BC, after their target cystic fibrosis transmembrane conductance regulator protein (CFTR) detection in BC. We used a drug repurposing approach to identify the target protein CFTR and drugs that target CFTR. MOE (molecular operating environment) was used to analyze the interaction between CFTR and its targeting drugs. For experimental work, we did Immunofluorescence staining on BC tissue. We found that glyburide and tezacaftor were the top antagonist and agonists, respectively. We detected CFTR expression in all ten samples except Triple-Negative Breast Cancer (TNBC). CFTR and estrogen receptor alpha co-expressed at 6.78%, suggesting a potential relationship. High-grade tumors showed CFTR expression below 8%, indicating CFTR down-regulation and its role in tumor aggressiveness. Our study is a preliminary step towards in-vitro and in-vivo experiments on repurposing CFTR-targeting drugs in BC. Glyburide may inhibit CFTR's estrogen production, while tezacaftor can enhance CFTR action to overcome tumor aggressiveness.
Side Effects and Genetic Variation During Depression in Taiwanese Han Population
Authors: Staff Editorial
Published: May 2024

Genetic variation can play a role in individual differences in the response to medications used for the treatment of depression, as well as in the occurrence of side effects. While there have been studies investigating genetic factors associated with antidepressant response and side effects, it is important to note that the field of pharmacogenetics is complex and influenced by multiple genetic and environmental factors. In the case of the Taiwanese Han population and depression, limited specific studies examining the relationship between genetic variation and antidepressant response or side effects have been conducted.  Huang and colleagues analyzed the syndromal factor structures of the Hamilton Depression Rating Scale in 479 patients with MDD by using exploratory factor analysis. All patients were followed up biweekly for 8 weeks. In total, 33 independent SNPs for treatment responses were tested in a mixed model, 12 of which demonstrated a p value <0.05. The most significant SNP was rs2182717 in the ENSR00000803469 gene located on chromosome 6 for the core syndromal factor (β = -0.638, p = 1.8 × 10-4) in terms of symptom improvement over time. Patients with a GG or GA genotype with the rs2182717 SNP also exhibited a treatment response (β = 0.089, p = 2.0 × 10-6) at week 4. Moreover, rs1836075352 was associated with sexual side effects (p = 3.2 × 10-8). Pathway and network analyses using the identified SNPs revealed potential biological functions involved in treatment response, such as neurodevelopment-related functions and immune processes. In conclusion, they identified loci that may affect the clinical response to treatment with antidepressants in the context of empirically defined depressive syndromal factors and side effects among the Taiwanese Han population, thus providing novel biological targets for further investigation. Pharmacogenomics J. 2023 May;23(2-3):50-59.  doi: 10.1038/s41397-023-00298-8.
Association of GABRG2 rs211037 Gene Polymorphism With Epilepsies and Pharmacoresistance to Anti-Epileptic Drugs; A Meta-Analysis
Authors: Ullah Shakir , Ali Saad , Ahmad Nisar , Zakria Muhammad , Nabi Muhammad , Ikram Muhammad
Published: May 2024

GABRG2 protein which is a crucial part of GABA receptor encoded by the gamma-aminobutyric acid A receptor, gamma 2 (GABRG2) gene. The exonic GABRG2 rs211037 gene polymorphism has been commonly explore with respect to variable association to different types of epilepsies (all types, IGE and FS) and AEDs response.  The current meta-analysis study was designed to explore whether the GABARG2 C588 T (rs211037) genetic variant predicts susceptibility to different types epilepsy and pharmacoresistance to AEDs. Twenty studies were included, contained 3351 epileptic patients and 3649 controls in meta-analysis, for the association GABRG2 rs211037 polymorphism with susceptibility to different types of epilepsy. Similarly, five studies comprised of 632 responder patients and 401 non-responder patients in meta-analysis, were selected for the evaluation of the GABRG2 rs211037 polymorphism to pharmacoresistance to AEDs. Meta-analysis was performed separately for FS and IGE in Asian and Caucasian population for association to epilepsies and pharmacoresistance to AEDs but pharmacoresistance to AEDs in FS and IGE was not performed in Asian and Caucasian due to limited number of studies. Meta-analysis showed a significant link between GABRG2 rs211037 polymorphism and susceptibility to all types of epilepsies in total Population in  (CC vs CT, OR 1.03, 95% CI 0.0–1.2, p = 0.0006 and CC vs TT, OR 0.03, 95% CI 0.8–1.2, p = 0.01) genetic models. Similarly, a significant association of this polymorphisms with all types of epilepsy was found with Asian population in genetic models of CC vs CT( OR 0.86 (0.7-1.0,p=0.11), CC vs TT (OR 0.67 (0.5-0.9, p=0.000), but  CC vs CT+TT genetic model shows the association of all types of epilepsies in Asian as well Caucasian population ( OR 0.6 (0.5-0.7), p=0.001 and OR 1.05 (0.9-1.2), p=0.000). Similarly, CC vs CT, CC vs TT and CC vs CT+TT genetic models were also associated with IGE and FS epilepsies in total population, Asian and Caucasian population. The alleles also showed a significant association with epilepsy. Genetic models of CC vs CT, CC vs TT and CC vs CT+TT were also associated with pharmacoresistance to AEDs (P<0.05) in total population, Asian and Caucasian population. The publication bias was not significant (P<0.05) but the heterogenicity (I2%) was mostly more than 50%. FS, caused by two studies with small sample sizes, however the possibility of false positive results because of significant studies for FS cannot be excluded. This study showed a significant association of GABRG2 rs211037 polymorphism with susceptibility to different types of epilepsies and pharmacoresistance to AEDs in all population. Future studies with larger sample sizes from different population are suggested to verify the results.
Search for the Natural Remedies for the Treatment of Gout
Authors: Bibi Hafsa , Shahid Tahreem , Ain Quratul
Published: May 2024

Gout is a well-known form of inflammatory arthritis, a condition that develops due to excessive synthesis and reduced excretion of uric acid. Extensively upregulated uric acid levels in the body culminate in the build-up of uric acid crystals in joints, tissues, and body fluids. Pain in the joints, heart, skin redness, and swelling, particularly at the base of the big toe, are the cardinal features.   Permanent joint damage may occur if gout is left untreated. Even though many drugs are established for gout therapy, these drugs cannot impede or reverse disease progression. Moreover, chronic use of these anti-gout agents is associated with several undesirable effects. A safe alternative to these synthetic drugs can be natural remedies. These natural remedies are found to subside symptoms of gout efficiently with the additional benefit of minimum or no side effects even after prolonged use. Traditional Chinese medicines have demonstrated better effects against gout than conventional therapies. The medicinal property of Malaysian and Morocco medicinal plants, Apium graveolens, Dendrobium candidum, Aristolochia baetica, Aristolochia paucinervis, Prunus avium, Prunus cerasus, Paullinia pinnata, Euphorbia hirta and Coffea arabica against gout are summarized in this article. This article aims to highlight the importance of these medicinal plants as a safe alternative to current conventional therapies against gout.
Chemical Composition, Antioxidant and Anticancer Potential of Anchusa arvensis
Authors: Hussain Sajid , Majid Shah Syed , Ali Fawad , Ullah Farman , Khan Sadozai Sahid , Bangash Hamza Hussain , Hussain Tahira
Published: May 2024

The purpose of this study was to investigate the phytochemical composition, antioxidant characteristics and cytotoxic effects of Anchusa arvensis (A. arvensis) crude extract (Aa.Cr) and its subsequent fractions: n-hexane (Aa.Hex), chloroform (Aa.Chm) , Ethylacetate (Aa.Et), and Aqueous (Aa.Aq). The antioxidant potential was determined using the Diphenyl-1-picrylhydrazyl (DPPH) and azinobis [3-ethylbenzthiazoline]-6-sulfonic acid (ABTS) radical scavenging assays. The sulforhodamine-B assay demonstrated anticancer activity against the human cancer cell line NCI-H460. Alkaloids, saponins, flavonoids, glycosides, and tannins were found in Aa.Cr. The Aa.Chm fraction showed the highest DPPH radical scavenging activity(74.83 ± 1.36%1.36%)  at 1000 µg/mL concentration. The extract fractions Aa.Hex and Aa.Et demonstrated moderate activity, while Aa.Aq showed poor radical scavenging activity. The results show that the Aa. Hex has significant ABTS radical scavenging activity with IC50.of 500μg/mL. Remarkable cytotoxicity was observed for chloroform (Aa.Chm) fraction with a growth inhibitory (GI50) ) value of 31 ± 0.6 µg/mL followed by Aa.Hex growth inhibitory (GI50) ) value of  (GI50 45 ± 5.7). The aqueous (Aa.Aq) and ethyl acetate (Aa.Et) fractions failed to display growth inhibitory effects against NCI-H460 cells. These findings indicate that Aa.Cr and its derived fractions possess antioxidant and anticancer effects.
Prevalence of Nonspecific Low Back Pain Among the Long Route Bus Drivers in Peshawar, Khyber Pakhtunkhwa, Pakistan
Authors: Afridi Baz Meer , Sikander Muhammad Suleman , Khan Habib , Ahmad Iftikhar
Published: May 2024

Low back pain (LBP) causes significant socioeconomic loss due to work-related musculoskeletal disorders (WMSDs). Prolonged sitting and vehicle vibration cause back pain, a typical complaint among long-route bus drivers. This study aimed to determine the frequency of job-related nonspecific LBP among long-route bus drivers in Peshawar, Pakistan. A descriptive cross-sectional study was conducted on 348 bus drivers working at three bus terminals (Haji Camp, Lahore, and Daewoo Bus Terminals). Data were gathered from January 2022 to June 2022 using a uniform, modified Nordic questionnaire. The mean age of drivers was 44. The results show a high prevalence of LBP at 93.4%. The most frequently impacted age group was in their fourth decade of life, and the least affected were the septuagenarians. According to the current study, job-related LBP was common among bus drivers. The study findings showed that long-route bus drivers are at continuous risk of developing nonspecific LBP due to long driving hours, with the driver's weight and age as additional risk factors.
Role of Non-verbal Communication Skills of Teachers and its Impact on Achieving Classroom Learning Objectives at Secondary Level
Authors: Munir Hina , Khan Aneela , Munawar Uzma
Published: May 2024

This descriptive study intends to investigate the influence of a teacher’s nonverbal communication on classroom learning objectives using a descriptive technique. This also determined the association between the unspoken behaviours of teachers working in various educational systems. The main objective of the research is to understand how non-verbal communication skills, including facial expressions, eye contact, pitch of voice, and physical appearance, collectively contribute to achieving classroom learning objectives. The quantitative survey method was used to present the study. This research was descriptive in nature. A 5-point Likert scale questionnaire was developed for data collection. This questionnaire was administered to a sample of 400 respondents who were randomly selected from 40 public and private secondary schools in Multan. Using SPSS software, the acquired data was tabulated and evaluated. The collected data was tabulated, analysed, and interpreted in the form of mean, frequency, percentage, and standard deviation. Both descriptive and inferential statistics were used to arrive at the conclusions. Frequencies and percentages were computed to illustrate the demographic items and questions, and one-way ANOVA and the independent sample t-test were utilized to illustrate the variations in teacher perspectives depending on various factors related to demographics.
Estrategias de Biotecnología Verde: Hacia una Recuperación Sostenible de Bosques Amazónicos
Authors: Conforme-Garcia Mariana Magdalena , Dávila-Ulloa Maricarmen , Sarango-Ordóñez Jhandry Patricio , Medina-Gahona Gladys Aracelli
Published: May 2024

Este estudio aborda el uso de estrategias de biotecnología verde para la recuperación sostenible de bosques amazónicos, destacando la sinergia entre tecnologías avanzadas y conocimientos tradicionales. Mediante una revisión bibliográfica cualitativa, se examinaron las aplicaciones y desafíos de estas estrategias, incluyendo la selección y mejora de especies autóctonas, técnicas de micorrización y el establecimiento de bancos de germoplasma. Los hallazgos sugieren un potencial significativo para fortalecer los esfuerzos de reforestación y conservación, aunque enfrentan obstáculos técnicos, logísticos y socioeconómicos, como la adaptación tecnológica al entorno amazónico y la necesidad de integrar a las comunidades locales en el proceso de conservación. La investigación resalta la importancia de combinar el conocimiento tradicional con innovaciones biotecnológicas para crear soluciones adaptativas y respetuosas. Sin embargo, la efectividad de estas tecnologías depende de superar desafíos de implementación mediante colaboraciones intersectoriales y el fortalecimiento de capacidades locales. Se enfatiza la necesidad de futuras investigaciones centradas en la adaptabilidad de las tecnologías de conservación a las condiciones de la Amazonía y en promover el diálogo entre científicos, comunidades indígenas y gestores de políticas para asegurar intervenciones sostenibles y culturalmente adecuadas.
Análisis de las principales causas de accidentes eléctricos con relación al entorno industrial del país
Authors: Jacome Alarcón Luis Fernando , León Enríquez Yisbell Mikaela , Macay Bernita Dariana Marleyni , Rodríguez Verdezoto Jina Alexandra
Published: May 2024

El marco de este estudio es comprender los comportamientos y condiciones que conducen a los accidentes en el lugar de trabajo, algunos de los factores más comunes son la falta de capacitación y educación adecuadas, mantenimiento deficiente, inspecciones de equipos eléctricos, la sobrecarga y el uso inadecuado de máquinas eléctricas. Por ello esta investigación pretende analizar las principales causas que conducen a que susciten accidentes de trabajo con la manipulación directa de los aparatos y equipos eléctricos en el área industrial, para con ello poder prevenir efectos adversos en la salud de las personas. La investigación fue de carácter descriptivo y documental, utilizando datos estadísticos que se analizaron a profundidad, es decir, basadas en la observación e investigación, familiarizadas con normativas y documentos legales vigentes aplicables asociados en la mitigación de casos de accidentes derivados por el inadecuado uso de equipos o maquinas eléctricas. Las cifras del IESS, en los últimos 6 años entre 2017 y 2022 se reportaron 91.581 accidentes laborales en Ecuador y entre febrero de 2020 y 2021, se registraron 10.821 accidentes laborales en el país. En conclusión, según estadísticas el 53% de los accidentes se dieron en el mismo lugar de trabajo, los estudios de estos casos son fundamentales para comprender y prevenir futuros accidentes.
Impacto del estrés laboral y trastornos mentales en médicos de Colombia en el marco de la identificación de los riesgos psicosociales del sistema de gestión y seguridad y salud en el trabajo, revisión bibliográfica
Authors: Benítez Jiménez Dilberth David , Reyes Navarro Gustavo Adolfo , Africano Ortigoza Kelly Alexandra , Tamayo Olmos Mónica Del Pilar
Published: May 2024

El presente artículo de revisión bibliográfica tiene como objetivo estimar la incidencia del estrés laboral y trastornos mentales en médicos de Colombia, en el marco de la identificación de riesgos psicosociales con enfoque al sistema de gestión de seguridad y salud en el trabajo. La metodología utilizada ha sido desde el enfoque cualitativo y el tipo de investigación ha sido la revisión bibliográfica, la cual se realizó desde la indagación en bases de datos especializadas y revistas indexadas, de donde se tomaron publicaciones realizadas en los últimos siete años.
El impacto de la creación de las judicaturas especializadas en materia constitucional en Ecuador: un análisis crítico
Authors: Chuquiguanga Lalvay Juan Pablo
Published: May 2024

Este artículo evalúa el impacto que tendrá la implementación de las judicaturas especializadas en materia constitucional en Ecuador, como una reforma destinada a mejorar la eficacia, eficiencia y accesibilidad del sistema judicial, enfocándose en la protección de los derechos constitucionales. Se empleó un enfoque cualitativo, utilizando una revisión bibliográfica de fuentes académicas, informes gubernamentales y documentos legales. La técnica de codificación temática permitió analizar y sintetizar la información. Las judicaturas han acelerado la resolución de casos y mejorado el acceso a la justicia, aunque subsisten problemas de calidad en la motivación de las sentencias, percepción de imparcialidad y presiones políticas. Se enfatiza en la necesidad de mejorar los recursos, la capacitación y la independencia judicial para optimizar el funcionamiento ético de las judicaturas en materia constitucional, para lo cual es esencial implementar reformas profundas para resolver las limitaciones actuales y fortalecer la confianza en la justicia.
Consumo de álcool e tabaco por gestantes assistidas na atenção primária
Authors: Brito Maria Fernanda Santos Figueiredo , Ferreira Thalita Bahia , Lima Cássio de Almeida , Freitas Anne Gracielle , Jesus Ludmila Cardoso Rodrigues , Silva Patrícia Oliveira , Oliva Aline Lara Cavalcante , Souza Meriele Santos , Freire Rafael Silveira , Silva Rosângela Ramos Veloso , Dias Orlene Veloso , Pinho Lucinéia de , Tibães Hanna Beatriz Bacelar
Published: May 2024

Este estudo tem como objetivo analisar o consumo de álcool e tabaco e os fatores associados entre gestantes assistidas na Atenção Primária à Saúde. Material e Métodos: Trata-se de uma pesquisa transversal aninhada numa coorte de base populacional realizada em Montes Claros, Minas Gerais - Brasil. Aplicou-se um questionário contemplando variáveis sobre uso de álcool e tabaco, características socioeconômicas, demográficas e psicossociais. Na análise de dados, efetuou-se estatística descritiva das variáveis, análise bivariada e regressão de Poisson para avaliar os fatores associados aos desfechos. Resultados: Foram pesquisadas 1279 gestantes e identificou-se que 147 (11,4%) relataram consumo de bebidas alcoólicas e 50 (3,9%) referiram tabagismo. Os fatores associados ao consumo de álcool foram: situação conjugal sem companheiro (RP=1,056; IC 95%=1,013-1,101), espiritualidade moderada (RP=1,095; IC 95%=1,049-1,143), pouca espiritualidade (RP=1,084; IC 95%=1,051-1,118), baixo apego materno-fetal/limítrofe (RP=1,165; IC 95%=0,993-1,366), presença de sintomas de estresse (RP=1,083; IC 95%=1,031-1,137). O tabagismo esteve associado aos fatores: escolaridade até o ensino médio (RP=0,936; IC 95%=0,896-0,978) e até ensino superior e/ou pós-graduação (RP=0,938; IC95%=0,893-0,985), renda familiar acima de R$ 2.000,00 (RP=0,972; IC 95%=0,949-0,997), disfuncionalidade familiar (RP=1,053; IC 95%=1,014-1,095). Notou-se importante prevalência do consumo de álcool e tabaco pelas gestantes, desfechos que foram relacionados a fatores sociodemográficos e psicossociais. Conclusão: O planejamento de políticas públicas de educação e acompanhamento pré-natal são essenciais para reduzir os riscos de morbidade de gestantes, fetos e recém nascidos. Torna-se premente fortalecer ações e estratégias para intervir na situação epidemiológica e traçar medidas de intervenção para redução do consumo de álcool e tabaco na gestação.
Trends in botanical education research: a bibliometric study
Authors: Saraiva Deisy Pereira , Santos Eulanda Miranda dos , Cantuária Patrick de Castro
Published: May 2024

A pesquisa em educação botânica busca cultivar uma apreciação profunda e um relacionamento responsável com a vida vegetal em nosso ambiente dinâmico. Este estudo emprega análise bibliométrica das bases de dados Scopus e WoS para revelar a trajetória do campo, as principais tendências e as áreas de pesquisa em desenvolvimento. Ele oferece insights valiosos para pesquisadores, educadores e formuladores de políticas, destacando ações promissoras para o avanço. Estas incluem o aumento da colaboração internacional, a integração de tecnologias digitais (por exemplo, experiências imersivas, aprendizagem gamificada) e o aproveitamento de espaços de aprendizagem informal como jardins botânicos, museus e herbários. Essas abordagens são promissoras para cultivar um futuro onde as plantas não sejam apenas valorizadas, mas protegidas ativamente.
BEZPIECZEŃSTWO W PRAKTYCE CZYLI JAK ĆWICZYĆ REAGOWANIE NA POTENCJALNE ZAGROŻENIA O CHARAKTERZE TERRORYSTYCZNYM? STUDIUM PRZYPADKU
Authors: Trocha Jerzy
Published: May 2024

W artykule przedstawiony został autorski sposób realizacji zajęć warsztatowych dotyczących reagowania na potencjalne zagrożenia o charakterze terrorystycznym, które z powodzeniem wykonywane były w ramach zajęć dydaktycznych na kierunku bezpieczeństwo wewnętrzne i penitencjarystyka w Akademii Wymiaru Sprawiedliwości oraz szkoleń zewnętrznych dla przedstawicieli władz samorządowych i pracowników urzędów w Polsce. W odpowiedzi na wysokie ryzyko wystąpienia ataku terrorystycznego w Europie autor zwrócił uwagę na potrzebę empirycznego kształcenia z tego obszaru w uczelniach wyższych. Bezpieczeństwa bowiem nie można uczyć ograniczając się wyłącznie do aspektów teoretycznych, dlatego też konieczne jest uzupełnienie wiedzy o praktykę. Autor dokonał omówienia sposobu organizacji warsztatów oraz scharakteryzował przyjęty zestaw ćwiczeń. Zastosowana struktura artykułu umożliwia zapoznanie się z elementarnymi podstawami dotyczącymi wybranych metod i form działania współczesnych terrorystów, a następnie przyjętej formy szkoleniowej.
MIĘDZYNARODOWA PRZESTĘPCZOŚĆ ZORGANIZOWANA.WYZWANIE DLA POKOJU, PRAWORZĄDNOŚCI I GLOBALNYCH DÓBR PUBLICZNYCH
Authors: Boćko Piotr
Published: May 2024

Temat jest rozległy i dość trudny do rozwiązania, ponieważ łączy trzy szerokie, otwarte i złożone koncepcje: przestępczość zorganizowaną, pokój i rządy prawa. Termin przestępczości zorganizowanej jest szeroki i obejmuje szeroki zakres działalności przestępczej. Handel ludźmi (w celu prostytucji, zmuszania do prostytucji lub pracy przymusowej), migracje, przemyt migrantów, handel narkotykami, handel nielegalnymi towarami, podrabianie towarów, handel narkotykami, handel dobrami kultury, handel bronią, napady z bronią w ręku i pranie brudnych pieniędzy. Istnieją również inne formy, choć mniej rozpowszechnione, takie jak piractwo, a także nowsze formy: cyberprzestępczość plus przestępczość przeciwko środowisku (formy: handel zwierzętami, pozyskiwanie drewna lub górnictwo, nielegalne rybołówstwo, nielegalne połowy, nielegalny handel odpadami itp.).
PODMIOTY EKONOMII SPOŁECZNEJ W WOJEWÓDZTWIE MAZOWIECKIM
Authors: Adamiak Katarzyna , Chyba Zbigniew , Czarnecka Wiktoria
Published: May 2024

Pojęcie ekonomii społecznej jest obecnie bardzo istotnym i aktualnym zagadnieniem. W literaturze coraz częściej pojawiają się rozważania na ten temat. W tym obszarze tematycznym istnieje w dalszym ciągu duża niejednorodność pojęciowa, a przyporządkowanie organizacji do kategorii podmiotów ekonomii społecznej jest dosyć trudnym zadaniem. W 2022 roku zaczęła obowiązywać Ustawa o ekonomii społecznej [1], która częściowo reguluje zagadnienia związane z tego typu podmiotami. Pomimo wprowadzonej regulacji prawnej w badanym obszarze istnieje szereg nieścisłości i aspektów, które należy poddawać dalszym badaniom i regularnym obserwacjom. Celem artykułu jest przedstawienie bieżącej sytuacji podmiotów ekonomii społecznej prowadzących działalność w województwie mazowieckim, podjęcie próby scharakteryzowania ich pod względem wybranych cech oraz przedstawienie rekomendacji, które posłużą optymalizacji pro-wadzonej przez nich działalności.