bluuebunny/crossref_metadata_2025 huggingface dataset:
Laser-driven low energy electron beams for single-shot ultra-fast probing of meso-scale materials and warm dense matter
Authors: Falk Katerina , Šmíd Michal , Boháček Karel , Chaulagain Uddhab , Gu Yanjun , Pan Xiayun , Perez-Martin Pablo , Krůs Miroslav , Kozlová Michaela
Published: March 2023

Laser wakefield acceleration has proven to be an excellent source of electrons and X-rays suitable for ultra-fast probing of matter. These novel beams have demonstrated unprecedented spatial and temporal resolution allowing for new discoveries in material science and plasma physics. In particular, the study of dynamic processes such as non-thermal melt and lattice changes on femtosecond time-scales have paved a way to completely new scientific horizons. Here, we demonstrate the first single-shot electron radiography measurement using an femtosecond electron source based on the downramp-density gradient laser-wakefield-acceleration with the use of a compact Ti:sapphire laser. A quasi-monoenergetic electron beam with mean energy of 1.9 ± 0.4 MeV and charge 77 ± 47 pC per shot was generated by the laser incident onto a gas target and collimated using a two ring-magnet beam path. High quality electron radiography of solid objects with spatial resolution better than 150 $$\upmu$$
μ
m was demonstrated. Further developments of this scheme have the potential to obtain single-shot ultrafast electron diffraction from dynamic lattices. This scheme poses a great promise for smaller scale university laboratories and facilities for efficient single-shot probing of warm dense matter, medical imaging and the study of dynamic processes in matter with broad application to inertial confinement fusion and meso-scale materials (mg g/cm$$^2$$

2

).
Isolation, characterization, proteome, miRNAome, and the embryotrophic effects of chicken egg yolk nanovesicles (vitellovesicles)
Authors: Saadeldin Islam M. , Tanga Bereket Molla , Bang Seonggyu , Seo Chaerim , Maigoro Abdulkadir Y. , Kang Heejae , Cha Dabin , Yun Sung Ho , Kim Seung Il , Lee Sanghoon , Cho Jongki
Published: March 2023

Egg yolk constitutes about a third of the structure of the chicken egg however, the molecular structure and physiological effects of egg yolk-derived lipid membranous vesicles are not clearly understood. In this study, for the first record, the egg yolk nanovesicles (vitellovesicles, VVs) were isolated, characterized, and used as a supplement for porcine embryo culture. Yolks of ten freshly oviposited eggs were filtered and ultracentrifuged at 100,000 × g for 3 h to obtain a pellet. Cryogenic transmission electron microscopy and nanoparticle tracking analysis of the pellet revealed bilipid membranous vesicles. Protein contents of the pellet were analyzed using tandem mass spectrometry and the miRNA content was also profiled through BGISEQ-500 sequencer. VVs were supplemented with the in vitro culture medium of day-7 hatched parthenogenetic blastocysts. After 2 days of blastocyst culture, the embryonic cell count was increased in VVs supplemented embryos in comparison to the non-supplemented embryos. TUNEL assay showed that apoptotic cells were increased in control groups when compared with the VVs supplemented group. Reduced glutathione was increased by 2.5 folds in the VVs supplemented group while reactive oxygen species were increased by 5.3 folds in control groups. Quantitative PCR analysis showed that VVs significantly increased the expression of lipid metabolism-associated genes (monoglyceride lipase and lipase E), anti-apoptotic gene (BCL2), and superoxide dismutase, while significantly reducing apoptotic gene (BAX). Culturing embryos on Matrigel basement membrane matrix indicated that VVs significantly enhanced embryo attachment and embryonic stem cell outgrowths compared to the non-supplemented group. This considers the first report to characterize the molecular bioactive cargo contents of egg yolk nanovesicles to show their embryotrophic effect on mammalian embryos. This effect might be attributed to the protein and miRNA cargo contents of VVs. VVs can be used for the formulation of in vitro culture medium for mammalian embryos including humans.
Polarity and mixed-mode oscillations may underlie different patterns of cellular migration
Authors: Plazen Lucie , Rahbani Jalal Al , Brown Claire M. , Khadra Anmar
Published: March 2023

In mesenchymal cell motility, several migration patterns have been observed, including directional, exploratory and stationary. Two key members of the Rho-family of GTPases, Rac and Rho, along with an adaptor protein called paxillin, have been particularly implicated in the formation of such migration patterns and in regulating adhesion dynamics. Together, they form a key regulatory network that involves the mutual inhibition exerted by Rac and Rho on each other and the promotion of Rac activation by phosphorylated paxillin. Although this interaction is sufficient in generating wave-pinning that underscores cellular polarization comprised of cellular front (high active Rac) and back (high active Rho), it remains unclear how they interact collectively to induce other modes of migration detected in Chinese hamster Ovary (CHO-K1) cells. We previously developed a six-variable (6V) reaction–diffusion model describing the interactions of these three proteins (in their active/phosphorylated and inactive/unphosphorylated forms) along with other auxiliary proteins, to decipher their role in generating wave-pinning. In this study, we explored, through computational modeling and image analysis, how differences in timescales within this molecular network can potentially produce the migration patterns in CHO-K1 cells and how switching between migration modes could occur. To do so, the 6V model was reduced to an excitable 4V spatiotemporal model possessing three different timescales. The model produced not only wave-pinning in the presence of diffusion, but also mixed-mode oscillations (MMOs) and relaxation oscillations (ROs). Implementing the model using the Cellular Potts Model (CPM) produced outcomes in which protrusions in the cell membrane changed Rac–Rho localization, resulting in membrane oscillations and fast directionality variations similar to those observed experimentally in CHO-K1 cells. The latter was assessed by comparing the migration patterns of experimental with CPM cells using four metrics: instantaneous cell speed, exponent of mean-square displacement ($$\alpha$$
α
-value), directionality ratio and protrusion rate. Variations in migration patterns induced by mutating paxillin’s serine 273 residue were also captured by the model and detected by a machine classifier, revealing that this mutation alters the dynamics of the system from MMOs to ROs or nonoscillatory behaviour through variation in the scaled concentration of an active form of an adhesion protein called p21-Activated Kinase 1 (PAK). These results thus suggest that MMOs and adhesion dynamics are the key mechanisms regulating CHO-K1 cell motility.
Post-truth epistemic beliefs rooted in the Dark Factor of Personality are associated with higher COVID-19 vaccination refusal
Authors: Rudloff Jan Philipp , Hutmacher Fabian , Appel Markus
Published: March 2023

A substantial number of people refused to get vaccinated against COVID-19, which prompts the question as to why. We focus on the role of individual worldviews about the nature and generation of knowledge (epistemic beliefs). We propose a model that includes epistemic beliefs, their relationship to the Dark Factor of Personality (D), and their mutual effect on the probability of having been vaccinated against COVID-19. Based on a US nationally representative sample (N = 1268), we show that stronger endorsement of post-truth epistemic beliefs was associated with a lower probability of having been vaccinated against COVID-19. D was also linked to a lower probability of having been vaccinated against COVID-19, which can be explained by post-truth epistemic beliefs. Our results indicate that the more individuals deliberately refrain from adhering to the better argument, the less likely they are vaccinated. More generally, post-truth epistemic beliefs pose a challenge for rational communication.
Climate-driven habitat shifts of high-ranked prey species structure Late Upper Paleolithic hunting
Authors: Yaworsky Peter M. , Hussain Shumon T. , Riede Felix
Published: March 2023

Changing climates in the past affected both human and faunal population distributions, thereby structuring human diets, demography, and cultural evolution. Yet, separating the effects of climate-driven and human-induced changes in prey species abundances remains challenging, particularly during the Late Upper Paleolithic, a period marked by rapid climate change and marked ecosystem transformation. To disentangle the effects of climate and hunter-gatherer populations on animal prey species during the period, we synthesize disparate paleoclimate records, zooarchaeological data, and archaeological data using ecological methods and theory to test to what extent climate and anthropogenic impacts drove broad changes in human subsistence observed in the Late Upper Paleolithic zooarchaeological records. We find that the observed changes in faunal assemblages during the European Late Upper Paleolithic are consistent with climate-driven animal habitat shifts impacting the natural abundances of high-ranked prey species on the landscape rather than human-induced resource depression. The study has important implications for understanding how past climate change impacted and structured the diet and demography of human populations and can serve as a baseline for considerations of resilience and adaptation in the present.
Investigation of eco-friendly fluorescence quenching probes for assessment of acemetacin using silver nanoparticles and acriflavine reagent
Authors: Ghonim Rana , El-Awady Mohamed I. , Tolba Manar M. , Ibrahim Fawzia A.
Published: March 2023

The non-steroidal anti-inflammatory medication acemetacin was assessed via two straightforward green spectrofluorimetric techniques. The quenching-dependent derivatizing spectrofluorimetric reactions are the master point of this study. Acriflavine-based method (Method I) depends on forming an ion association complex between acriflavine and the drug in a ratio of 1:1, decreasing the former's fluorescence intensity. Acriflavine or Ag NP's intensity-related quenching action goes linearly with the acemetacin concentration in the 2.0–20.0 µg/mL and 1.0–16.0 µg/mL ranges, respectively. The second quenching mechanism depends on using the silver nanoparticles (Ag NP's) as a fluorescence probe (Method II); Ag NP's were prepared from reducing silver nitrate using sodium borohydride. Both methods could be applied to determine pure and pharmaceutical dosage forms of acemetacin. The methods proved valid according to the international conference on harmonization (ICH) guidelines. In addition to this, this work has been estimated under green criteria assessment tools. There is no significant difference between the proposed and the comparison methods after the statistical interpretation.
Differential toxicity profile of secreted and processed α-Klotho expression over mineral metabolism and bone microstructure
Authors: Roig-Soriano Joan , Sánchez-de-Diego Cristina , Esandi-Jauregui Jon , Verdés Sergi , Abraham Carmela R. , Bosch Assumpció , Ventura Francesc , Chillón Miguel
Published: March 2023

The aging-protective gene α-Klotho (KL) produces two main transcripts. The full-length mRNA generates a transmembrane protein that after proteolytic ectodomain shedding can be detected in serum as processed Klotho (p-KL), and a shorter transcript which codes for a putatively secreted protein (s-KL). Both isoforms exhibit potent pleiotropic beneficial properties, although previous reports showed negative side effects on mineral homeostasis after increasing p-KL concentration exogenously. Here, we expressed independently both isoforms using gene transfer vectors, to assess s-KL effects on mineral metabolism. While mice treated with p-KL presented altered expression of several kidney ion channels, as well as altered levels of Pi and Ca2+ in blood, s-KL treated mice had levels comparable to Null-treated control mice. Besides, bone gene expression of Fgf23 showed a fourfold increase after p-KL treatment, effects not observed with the s-KL isoform. Similarly, bone microstructure parameters of p-KL-treated mice were significantly worse than in control animals, while this was not observed for s-KL, which showed an unexpected increase in trabecular thickness and cortical mineral density. As a conclusion, s-KL (but not p-KL) is a safe therapeutic strategy to exploit KL anti-aging protective effects, presenting no apparent negative effects over mineral metabolism and bone microstructure.
Genome editing of the vermilion locus generates a visible eye color marker for Oncopeltus fasciatus
Authors: Reding Katie , Lê Minh , Pick Leslie
Published: March 2023

Insects display a vast array of eye and body colors. Genes encoding products involved in biosynthesis and deposition of pigments are ideal genetic markers, contributing, for example, to the power of Drosophila genetics. Oncopeltusfasciatus is an emerging model for hemimetabolous insects, a member of the piercing-sucking feeding order Hemiptera, that includes pests and disease vectors. To identify candidate visible markers for O.fasciatus, we used parental and nymphal RNAi to identify genes that altered eye or body color while having no deleterious effects on viability. We selected Of-vermilion for CRISPR/Cas9 genome editing, generating three independent loss-of-function mutant lines. These studies mapped Of-vermilion to the X-chromosome, the first assignment of a gene to a chromosome in this species. Of-vermilion homozygotes have bright red, rather than black, eyes and are fully viable and fertile. We used these mutants to verify a role for Of-xdh1, ortholog of Drosophilarosy, in contributing to red pigmentation using RNAi. Rather than wild-type-like red bodies, bugs lacking both vermilion and xdh1 have bright yellow bodies, suggesting that ommochromes and pteridines contribute to O.fasciatus body color. Our studies generated the first gene-based visible marker for O.fasciatus and expanded the genetic toolkit for this model system.
Visualizing genomic characteristics across an RNA-Seq based reference landscape of normal and neoplastic brain
Authors: Arora Sonali , Szulzewsky Frank , Jensen Matt , Nuechterlein Nicholas , Pattwell Siobhan S. , Holland Eric C.
Published: March 2023

In order to better understand the relationship between normal and neoplastic brain, we combined five publicly available large-scale datasets, correcting for batch effects and applying Uniform Manifold Approximation and Projection (UMAP) to RNA-Seq data. We assembled a reference Brain-UMAP including 702 adult gliomas, 802 pediatric tumors and 1409 healthy normal brain samples, which can be utilized to investigate the wealth of information obtained from combining several publicly available datasets to study a single organ site. Normal brain regions and tumor types create distinct clusters and because the landscape is generated by RNA-Seq, comparative gene expression profiles and gene ontology patterns are readily evident. To our knowledge, this is the first meta-analysis that allows for comparison of gene expression and pathways of interest across adult gliomas, pediatric brain tumors, and normal brain regions. We provide access to this resource via the open source, interactive online tool Oncoscape, where the scientific community can readily visualize clinical metadata, gene expression patterns, gene fusions, mutations, and copy number patterns for individual genes and pathway over this reference landscape.
Characterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate
Authors: Satofuka Hiroyuki , Wang Yayan , Yamazaki Kyotaro , Hamamichi Shusei , Fukuhara Takeshi , Rafique Abdur , Osako Nana , Kanazawa Iori , Endo Takeshi , Miyake Naomi , Honma Kazuhisa , Nagashima Yuichi , Hichiwa Genki , Shimoya Kazuto , Abe Satoshi , Moriwaki Takashi , Murakami Yasufumi , Gao Xu , Kugoh Hiroyuki , Oshimura Mitsuo , Ito Yuji , Kazuki Yasuhiro
Published: March 2023

We previously generated fully human antibody-producing TC-mAb mice for obtaining potential therapeutic monoclonal antibodies (mAbs). In this study, we investigated 377 clones of fully human mAbs against a tumor antigen, epithelial cell adhesion molecule (EpCAM), to determine their antigen binding properties. We revealed that a wide variety of mAbs against EpCAM can be obtained from TC-mAb mice by the combination of epitope mapping analysis of mAbs to EpCAM and native conformational recognition analysis. Analysis of 72 mAbs reacting with the native form of EpCAM indicated that the EpCL region (amino acids 24–80) is more antigenic than the EpRE region (81–265), consistent with numerous previous studies. To evaluate the potential of mAbs against antibody–drug conjugates, mAbs were directly labeled with DM1, a maytansine derivative, using an affinity peptide-based chemical conjugation (CCAP) method. The cytotoxicity of the conjugates against a human colon cancer cell line could be clearly detected with high-affinity as well as low-affinity mAbs by the CCAP method, suggesting the advantage of this method. Thus, this study demonstrated that TC-mAb mice can provide a wide variety of antibodies and revealed an effective way of identifying candidates for fully human ADC therapeutics.
Influence of the emulsifier on nanostructure and clinical application of liquid crystalline emulsions
Authors: Teeranachaideekul Veerawat , Soontaranon Siriwat , Sukhasem Supreeya , Chantasart Doungdaw , Wongrakpanich Amaraporn
Published: March 2023

Liquid crystals are appealing in pharmaceutical and cosmetic fields due to their unique structures that combine the properties of both liquid and solid states. Forming an emulsion into liquid crystals can be affected by a number of factors, including the emulsion composition and temperature. Changing the types and concentrations of surfactants could be another factor that affects liquid crystals. Currently, most liquid crystal research focuses on the nanostructure of liquid crystal systems without evaluating the efficacy of liquid crystals clinically. In this study, liquid crystalline emulsions made from camellia seed oil with four different surfactants (Olivem 1000, Polyaquol-2W, Nikkomulese LC, and Lecinol S-10 with Tween 80) were created. The liquid crystal emulsions were formulated in the form of oil-in-water (o/w) emulsions with Camellia oleifera seed oil serving as the main ingredient in the oil phase (10% w/w). All formulations exhibited liquid crystal characteristics with lamellar structures as determined by the polarized light microscopy and small-angle X-ray scattering with supporting data of the nanostructure from wide-angle X-ray scattering and differential scanning calorimetry (DSC). They all showed good stability under normal (room temperature) and accelerated conditions (4 °C and 40 °C) in long-term storage (6 months). Using the reconstructed human epidermis as a skin model, all formulations did not cause skin irritation. In the clinical trial, all formulations were able to reduce transepidermal water loss (TEWL) and increase skin hydration immediately after application. This lasted at least 10 h. All formulations showed distinct Maltese crosses under the polarized light microscope with a positive result for liquid crystals in wide angle X-ray scattering (WAXS) and small angle X-ray scattering (SAXS) methods. Moreover, among all formulations tested, Formulation D, which contained Lecinol S-10 and Tween 80 as emulsifiers, showed the most robust interaction between the surfactant and water molecules in the lamellar structure under DSC. The formulation was stable in long-term normal and accelerated conditions. Above all, Formulation D, which was formulated with Lecinol S-10 with Tween 80, had the best clinical result, was nonirritating to the skin, and can be used as a cream base in the pharmaceutical and cosmeceutical sectors.
Effects of copal resin extraction on the diversity and composition of species in tropical deciduous forests
Authors: García-Núñez Rosa María , Buendía-Espinoza Julio César , del Carmen Arrazate-Jiménez Selene , del Carmen Martínez-Ochoa Elisa
Published: March 2023

Composition and floristic diversity of ecosystems subject to overexploitation, such as tropical deciduous forests where copal resin (Bursera bipinnata, Bursera copallifera) is extracted, are of great importance for understanding the ecological functioning of these ecosystems. This study analyzed the species composition and diversity in a natural population subject to copal extraction in San Juan Raboso Izúcar de Matamoros, Puebla, Mexico. A total of 54 sampling units were established, and the number of individuals and crown diameter for each tree species were recorded. For shrubs, succulents, acaulescent rosetophytes and climbers, the number of individuals and the area of cover were quantified. Based on the parameters of abundance, frequency, and relative dominance, the importance value index (IVI) was calculated. Diversity was evaluated using the Shannon index $$(H {^{\prime}})$$

(
H

′

)

. In total, 29 species were identified, distributed across 11 botanical families and 21 genera. The Fabaceae family was the richest, followed by the Burseraceae family, which includes the species that extract copal, but Opuntia streptacantha was the species with the most ecological weight. In this study, the Shannon index $$({H}^{^{\prime}})$$

(

H

′

)

averaged 1.45, which indicates that the community was mildly diverse.
Intense multicycle THz pulse generation from laser-produced nanoplasmas
Authors: Kumar Manoj , Song Hyung Seon , Lee Jaeho , Park Dohyun , Suk Hyyong , Hur Min Sup
Published: March 2023

We present a novel scheme to obtain robust, narrowband, and tunable THz emission using a nano-dimensional overdense plasma target, irradiated by two counter-propagating detuned laser pulses. So far, no narrowband THz sources with a field strength of GV/m-level have been reported from laser-solid interaction (mostly half-or single-cycle THz pulses with only broadband frequency spectrum). From two- and three-dimensional particle-in-cell simulations, we find that the strong plasma current generated by the beat ponderomotive force in the colliding region, produces beat-frequency radiation in the THz range. Here we report intense THz pulses $$(f\simeq 30 \;$$

(
f
≃
30

THz) with an unprecedentedly high peak field strength of 11.9 GV/m and spectral width $$(\Delta f/f\simeq 5.3\%)$$

(
Δ
f
/
f
≃
5.3
%
)

, which leads to a regime of an extremely bright narrowband THz source of TW/cm$$^{2}$$

2

, suitable for various ambitious applications.
Development of substrates for the culture of human pluripotent stem cells
Authors: Kawase Eihachiro , Nakatsuji Norio
Published: March 2023

This review provides the latest progress of culture substrates for human pluripotent stem cells.
Split-tracrRNA as an efficient tracrRNA system with an improved potential of scalability
Authors: Park Jihyun , Kang Seong Jae , Go Seulgi , Lee Jeongmin , An Jinsu , Chung Hak Suk , Jeong Cherlhyun , Ahn Dae-Ro
Published: March 2023

The split-tracrRNA system composed of two fragments of the conventional tracrRNA was developed for improved scalability. The optimized split-tracrRNA showed gene editing efficiency and specificity comparable to those of the conventional tracrRNA.
Fe and C additions decrease the dissolution rate of silicon nitride coatings and are compatible with microglial viability in 3D collagen hydrogels
Authors: Echeverri Estefanía , Skjöldebrand Charlotte , O'Callaghan Paul , Palmquist Anders , Kreuger Johan , Hulsart-Billström Gry , Persson Cecilia
Published: March 2023

The possibility of decreasing the dissolution rate of SiN coatings using Fe and C is promising and the released ions were demonstrated to be compatible with microglia viability, in both 2D cultures and 3D collagen hydrogels.
CuO/NaNbO3 nanorod piezoelectric photocatalysts promoted tetracycline removal: a dynamic internal electric field
Authors: Wang Hongtao , Zhang Haiyue , Long Ziyang , Shi Haifeng
Published: March 2023

The piezoelectric electric field inside CuO/NaNbO3 nanorods promoted the separation of photoinduced carriers and inhibited being saturated by free carriers.
Chronic exposure to complex metal oxide nanomaterials induces production of reactive oxygen species in bacteria
Authors: Sharan Deepti , Wolfson Daniel , Green Curtis M. , Lemke Paul , Gavin Alessandra G. , Hamers Robert J. , Feng Z. Vivian , Carlson Erin E.
Published: March 2023

Chronic exposure of Shewanella oneidensis to nanoscale lithiated nickel manganese cobalt oxide induces ROS production in the bacteria, filamentation, vesicle formation, DNA damage, and evolution of resistance to other stressors such as antibiotics.
Lactobacillus plantarum ZJ316 alleviates ulcerative colitis by inhibiting inflammation and regulating short-chain fatty acid levels and the gut microbiota in a mouse model
Authors: Gu Qing , Xia Chenlan , Liu Nana , Chen Ziqi , Zhou Qingqing , Li Ping
Published: March 2023

Lactobacillus plantarum ZJ316 alleviates DSS-induced UC symptoms in mice by regulating intestinal microbiome.
Effect ofGinkgo bilobaextract on pharmacology and pharmacokinetics of atorvastatin in rats with hyperlipidaemia
Authors: Wang Qingqing , Liu Zihou , Wang Rui , Li Run , Lian Xiaoru , Yang Yanquan , Yan Jiao , Yin Zhiqi , Wang Guangji , Sun Jianguo , Peng Ying
Published: March 2023

Ginkgo bilobaextract provides synergistic and attenuated benefits to atorvastatin in the treatment of hyperlipidemia by improving the endogenous metabolic abnormalities and increasing statin exposure in the body.
Green one-pot synthesis of bimetallic Pd–Pt nanosponges using biomolecules with enhanced catalytic activity for hydrogen evolution reactions
Authors: Topuz Fuat , Patil Bhushan , Uyar Tamer
Published: March 2023

Green one-pot synthesis of bimetallic nanoparticles of Pd and Pt using RNA molecules as the capping/stabilizing agent and ascorbic acid as the reducing agent was described.
Green synthesis of silver nanoparticles: methods, biological applications, delivery and toxicity
Authors: Vidyasagar  , Patel Ritu Raj , Singh Sudhir Kumar , Singh Meenakshi
Published: March 2023

Schematic representation of the green synthesized silver nanoparticles, its types, mode of delivery and several biological applications.
Sustained release of tumor cell lysate and CpG from an injectable, cytotoxic hydrogel for melanoma immunotherapy
Authors: Yang Kui , Zhou Yuhan , Huang Biwang , Zhao Guifang , Geng Yuan , Wan Chao , Jiang Fagang , Jin Honglin , Ye Chengzhi , Chen Jing
Published: March 2023

The fabrication of MCL and the mechanism of MCL-mediated antitumor effects against melanoma.
Biomimetic nanoparticles for DC vaccination: a versatile approach to boost cancer immunotherapy
Authors: Meng Lingyang , Teng Zhuang , Yang Shuang , Wang Na , Guan YingHua , Chen Xiguang , Liu Ya
Published: March 2023

The incorporation of biomimetic nanoparticles into the DC vaccination strategies has shown outstanding advantages in precisely directing the immune system to fight cancer.
Thermo-responsive block copolymers: assembly and application
Authors: Shao Guangran , Liu Yuan , Cao Rong , Han Guang , Yuan Bing , Zhang Wangqing
Published: March 2023

The review focuses on the assembly and application of five thermo-responsive block copolymers containing one or two thermo-responsive blocks, and aims to provide an overview to guide the design of these copolymers and stimulate more applications.
Progress of transition metal sulfides used as lithium-ion battery anodes
Authors: Wang Shaochen , Qu Chenwei , Wen Jiawei , Wang Chunxia , Ma Xinlong , Yang Yue , Huang Guoyong , Sun Hongyu , Xu Shengming
Published: March 2023

TMS used as high-capacity anodes in Li-ion batteries are thoroughly reviewed.
Synthesis and characterization of silver nanoparticle embedded cellulose–gelatin based hybrid hydrogel and its utilization in dye degradation
Authors: Saruchi  , Kumar Vaneet , Bhatt Diksha , Pandey Sadanand , Ghfar Ayman A.
Published: March 2023

The present work describes the synthesis of a cellulose and gelatin based hydrogel by the grafting of poly(acrylic acid) using ammonium persulphate (APS)-glutaraldehyde as the initiator–crosslinker system.
Fabrication and desired properties of conductive hydrogel dressings for wound healing
Authors: Nie Lei , Wei Qianqian , Li Jingyu , Deng Yaling , He Xiaorui , Gao Xinyue , Ma Xiao , Liu Shuang , Sun Yanfang , Jiang Guohua , Okoro Oseweuba Valentine , Shavandi Amin , Jing Shengli
Published: March 2023

Conductive hydrogels are recognized as promising materials for wound healing. Valuable properties of conductive hydrogels suggest the possibility of their use as an alternative wound dressing to traditional dressings such as bandages.
Cancer nanomedicine: a review of nano-therapeutics and challenges ahead
Authors: Nirmala M. Joyce , Kizhuveetil Uma , Johnson Athira , G Balaji , Nagarajan Ramamurthy , Muthuvijayan Vignesh
Published: March 2023

Approaches to overcome the challenges of cancer nanomedicine drug discovery process.
Corrosion protection properties of tetraphenylethylene-based inhibitors toward carbon steel in acidic medium
Authors: Chen Yumeng , An Yiming , Ma Jing , Zhang Zhihua , Qiao Fulin , Lei Xue , Sun Fei , Wang Chunlu , Gao Song , Zhao Yue , Wang Jinhua , Fu Xiaoping , Wang Hui , Yu Zhengqi
Published: March 2023

Four corrosion inhibitors containing tetraphenylethylene were synthesized and proved to protect carbon steel effectively in acidic medium.
Effect of cation alkyl chain length on 3-sulfopropylmethacrylate-based draw solutes having lower critical solution temperature
Authors: Moon Jihyeon , Kang Hyo
Published: March 2023

The applicability of 3-sulfopropyl methacrylate-based ionic liquids having lower critical solution temperature characteristics as draw solutes for forward osmosis processes was investigated by varying the alkyl chain length of the cation.
Biomimetic chlorine-induced polyene cyclizations harnessing hypervalent chloroiodane–HFIP assemblies
Authors: Binder Julia , Biswas Aniruddha , Gulder Tanja
Published: March 2023

A selective and generally applicable concept of the yet scantly investigated chlorination-induced polyene cyclization utilizing HFIP–chloroiodane networks mimicking terpene cyclase has been developed.
Triarylamines as catalytic donors in light-mediated electron donor–acceptor complexes
Authors: Castillo-Pazos Durbis J. , Lasso Juan D. , Hamzehpoor Ehsan , Ramos-Sánchez Jorge , Salgado Jan Michael , Cosa Gonzalo , Perepichka Dmytro F. , Li Chao-Jun
Published: March 2023

EDA complexes with catalytic triarylamines allow C–H perfluoroalkylation of arenes and heteroarenes under visible light irradiation in pH- and redox-neutral conditions. A detailed photophysical characterization of the EDA complex is provided.
Visible label-free detection of bacterial DNA using flocculation of sterically stabilised cationic latexes
Authors: Trinh Elisabeth , Thompson Kate L. , Wen Shang-Pin , Humphreys Gavin J. , Price Bianca L. , Fielding Lee A.
Published: March 2023

This paper demonstrates a method for detecting the presence of amplified DNA from bacterial samples using a sterically-stabilised, cationic polymer latex and widely available equipment, providing an accessible alternative DNA detection technique.
Effect of composition gradient on domain structure and piezoelectric properties in Mn-doped KNN single crystals
Authors: Zhang Yao , Hu Chengpeng , Wang Yu , Huang Xiaolin , Sun Xuejie , Liu Mingxuan , Xing Bohan , Wen Xing , Tian Hao
Published: March 2023

Large Ein induces a more ordered, large-size striated domain structure. The Mn: KNN single crystal with a large CG has a uniform orientation of spontaneous polarization and large macro-piezoelectric properties (83 pC N−1).
Impacts of framework Al distribution and acidic properties of Cu-exchanged CHA-type zeolite on catalytic conversion of methane into methanol followed by lower hydrocarbons
Authors: Nakamura Kengo , Xiao Peipei , Osuga Ryota , Wang Yong , Yasuda Shuhei , Matsumoto Takeshi , Kondo Junko N. , Yabushita Mizuho , Muramatsu Atsushi , Gies Hermann , Yokoi Toshiyuki
Published: March 2023

This work highlighted the significance of the Al distribution in the CHA-type zeolite in the formation of active Cu species for the oxidative conversion of CH4; isolated Al atoms in the zeolite framework are found to be advantageous for producing CH3OH.
Molecular sonification for molecule to music information transfer
Authors: Mahjour Babak , Bench Jordan , Zhang Rui , Frazier Jared , Cernak Tim
Published: March 2023

Organic chemical structures can be encoded as a simple musical phrase.
The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind randomized controlled trial
Authors: Foshati Sahar , Poursadeghfard Maryam , Heidari Zahra , Amani Reza
Published: March 2023

Ginger supplementation may be a safe and effective adjuvant therapy for patients with relapsing-remitting multiple sclerosis.
Health potential of fermented goat dairy products: composition comparison with fermented cow milk, probiotics selection, health benefits and mechanisms
Authors: Chen Li , Bagnicka Emilia , Chen He , Shu Guowei
Published: March 2023

Probiotics used in goat milk fermentation include lactic acid bacteria and kefir grains. Fermented goat milk has a better nutritional composition. Health benefits of fermented goat dairy products are reviewed and possible mechanisms are discussed.
Simple engineering of hybrid cellulose nanocrystal–gold nanoparticles results in a functional glyconanomaterial with biomolecular recognition properties
Authors: Biagiotti Giacomo , Toniolo Gianluca , Albino Martin , Severi Mirko , Andreozzi Patrizia , Marelli Marcello , Kokot Hana , Tria Giancarlo , Guerri Annalisa , Sangregorio Claudio , Rojo Javier , Berti Debora , Marradi Marco , Cicchi Stefano , Urbančič Iztok , van Kooyk Yvette , Chiodo Fabrizio , Richichi Barbara
Published: March 2023

Hybrid cellulose nanocrystal-gold nanoparticles engineered with sugar headgroups is a functional glyconanomaterial that permits a direct visualization of the sugar headgroups-lectins interactions by cryo-transmission electron microscopy.
Large-scale fabrication and Mo vacancy-induced robust room-temperature ferromagnetism of MoSe2 thin films
Authors: Zhong Jing , Zhang Xi , He Wa , Gong Dan , Lan Mu , Dai Xu , Peng Yong , Xiang Gang
Published: March 2023

Large-scale (4 cm × 4 cm) MoSe2 thin films with Mo Vacancy-induced robust RTFM (Ms = 6.69 emu g-1, Hc = 5 Oe) and smooth surface (roughness average ∼0.22 nm) are prepared by PAD method.
Diruthenium(ii,iii) paddlewheel complexes: effects of bridging and axial ligands on anticancer properties
Authors: Tolbatov Iogann , Barresi Elisabetta , Taliani Sabrina , La Mendola Diego , Marzo Tiziano , Marrone Alessandro
Published: March 2023

Diruthenium(ii,iii) paddlewheel carboxylates combine the pharmacological properties of the dimetallic center with those ascribed to the μ-bridged carboxylates, thus leading to novel, dual-acting anticancer metallodrugs.
The nonclassical crystallization mechanism and growth kinetics of densely packed fluorapatite nanorod arrays: effects of the ion transportation rate and fluoride concentration
Authors: Cai Meng , Wang Yiting , Wan Luyao , Ping Hang , Wang Wenxuan , Wang Weimin , Wang Hao , Zou Zhaoyong , Fu Zhengyi
Published: March 2023

FAP arrays form via a nanoparticle assembly route and an appropriate ion transportation rate and increasing fluoride concentration can accelerate the mineralization rate.
Palladium-catalyzed allylic allenylation of homoallyl alcohols with propargylic carbonates
Authors: Zhou Ping-Xin , Wang Murong , Li Xiang , Du Xueyan , Yang Xiaozhe , Wang Han , Sun Tangqiang , Ren Feng , Liang Yong-Min
Published: March 2023

A palladium-catalyzed reaction of homoallyl alcohols with propargylic carbonates was realized via oxidative addition/decarboxylation/retro-allylation.
Facile preparation of nickel phosphide for enhancing the photoelectrochemical water splitting performance of BiVO4 photoanodes
Authors: Li Yongsheng , Li Zhen , Xu Chengwen , Yu Shuangwei , Sun Zijun
Published: March 2023

Herein, nickel phosphides with different stoichiometry (Ni2P and Ni12P5) were successfully modified on the surface of BiVO4 photoanode for enhancing the PEC water splitting performance.
Chemically functionalized manufactured sand as the novel additive for enhancing the properties of cement-based composites
Authors: Wo Jiangang , Wang Di , Zhang Ting , Shi Chengfang , Zhou Zhengfa , Wang Aiguo , Wang Wenping
Published: March 2023

The PCE was grafted onto manufactured sand to produce better dispersed particles, which can improve the performance of cement-based materials.
Employing non-canonical amino acids towards the immobilization of a hyperthermophilic enzyme to increase protein stability
Authors: Switzer Hannah J. , Howard Christina A. , Halonski John F. , Peairs Emily M. , Smith Nolan , Zamecnik Maddy P. , Verma Sanjana , Young Douglas D.
Published: March 2023

A carboxylesterase derived from Sulfolobus solfataricus P1 was immobilized onto an epoxy-activated Sepharose resin via non-canonical amino acids.
Interfacial construction of P25/Bi2WO6 composites for selective CO2 photoreduction to CO in gas–solid reactions
Authors: Liu Daohan , Zeng Minli , Li Zhen , Zhu Zhiqi , Chen Yu , Thummavichai Kunyapat , Ola Oluwafunmilola , Wang Nannan , Zhu Yanqiu
Published: March 2023

Proposed mechanism of CO2 photoreduction of the P25/Bi2WO6 nanocomposites.
Theoretical study on the mechanism of water oxidation catalyzed by a mononuclear copper complex: important roles of a redox non-innocent ligand and HPO42−anion
Authors: Li Ying-Ying , Wang Xiao-Yan , Li Hui-Ji , Chen Jia-Yi , Kou Yao-Hua , Li Xiao , Wang Yaping
Published: March 2023

DFT calculations suggest the redox non-innocent role of the ligand and proton-accepting role of HPO42−are beneficial for the water oxidation catalyzed by a mononuclear copper complex.
CaGdF5 based heterogeneous core@shell upconversion nanoparticles for sensitive temperature measurement
Authors: Xie Xiaoyu , Wang Wang , Chen Haoran , Yang Run , Wu Han , Gan Dechao , Li Bin , Kong Xianggui , Li Qiqing , Chang Yulei
Published: March 2023

The heterogeneous core@shell UCNPs are promising for optical temperature sensors.
Using the similarity theory and dimensional analysis to quantify the periodic dependence of the properties of chemical elements
Authors: Protsenko Vyacheslav S.
Published: March 2023

Similarity theory and dimensional analysis were used to quantify the “periodic” law. The dependences of the properties of chemical elements on their atomic numbers are superpositions of a series of oscillations.
Empowering boronic acids as hydroxyl synthons for aryne induced three-component coupling reactions
Authors: Fan Rong , Liu Shihan , Yan Qiang , Wei Yun , Wang Jingwen , Lan Yu , Tan Jiajing
Published: March 2023

Boronic acids as a tunable hydroxy source display a unique reactivity paradigm through hitherto unknown aryne-induced multicomponent reactions.
Buckybowl and its chiral hybrids featuring eight-membered rings and helicene units
Authors: Duan Yuxiao , Chen Meng , Hayashi Hironobu , Yamada Hiroko , Liu Xinyue , Zhang Lei
Published: March 2023

A novel buckybowl and its chiral hybrids featuring eight-membered rings and helicene units have been synthesized and characterized. The resulting hybrid and its complex with C60 show promising ambipolar transport characteristics.
A CoPd nanoalloy embedded N-doped porous carbon catalyst for the selective reduction and reductive amination of levulinic acid using formic acid in water
Authors: Kar Ashish Kumar , Chauhan Arzoo , Srivastava Rajendra
Published: March 2023

Formic acid-mediated levulinic acid valorization was conducted using a CoPd nanoalloy embedded N-doped carbon catalyst for the production of γ-valerolactone and pyrrolidones.
Two-dimensional layered Dion–Jacobson phase organic–inorganic tin iodide perovskite field-effect transistors
Authors: Ji Hongyu , Liu Xin , Li Longtao , Zhang Fan , Qin Liang , Lou Zhidong , Li Dan , Hu Yufeng , Hou Yanbing , Teng Feng
Published: March 2023

The single BDA2+layer in D–J BDASnI4eliminates the van der Waals gap in R–P perovskites, enhancing the out-of-plane charge transport and structural stability. Polymer-gated BDASnI4FETs show improved performance and environmental stability.
Prespecifiable fixed‐time control for uncertain nonlinear system with input quantization
Authors: Gao Yang , Ma Jiali , Chen Qingwei , Wu Yifei , Qian Chen
Published: March 2023

This paper focuses on the global prespecifiable fixed‐time control problem of uncertain strict‐feedback nonlinear system with input quantization. In contrast to the existing fixed‐time control results, the signs of the control gains can be unknown in our paper. Unlike the traditional fixed‐time control schemes, some exponential functions are added into the virtual controllers to accelerate the convergence rate. Besides, some dynamic switching functions are also introduced to compensate the unknown control signs. Based on the novel regulate law, the switching functions can be regulated online to ensure the fixed‐time stability for the considered system. Furthermore, the settling time can be easily adjusted by selecting the controller parameters. Simulation results are provided to illustrate the effectiveness of the proposed control scheme.
Comparative analysis of antenna isolation characteristic with & without self‐interference reduction techniques towards in‐band full‐duplex operation
Authors: Yalcinkaya Merve Tascioglu , Sen Padmanava , Fettweis Gerhard
Published: March 2023

The advancement of communication and radar systems has triggered the demand for in‐band full‐duplex (IBFD) operation. IBFD is regarded as one of the most outstanding technologies in terms of its ability to improve spectral efficiency and data rate. IBFD operation has the potential not only to enable communication or radar systems separately, but to help realising radar sensing and communication at the same time, known as Joint Communication and Sensing (JC&S) technology. In realisation of IBFD and JC&S systems, self‐interference (SI) is the key challenge for antenna designers. In this article, a comprehensive survey on SI reduction techniques in the antenna domain is provided and the advantages and disadvantages of each technique are studied. SI reduction techniques have been proposed separately but an elaborated review of relevant techniques with a comparative study has not been presented yet. For the first time, a systematic comparative study of different SI reduction techniques is graphically presented to cover a comparison based on isolation, gain, and impedance bandwidth in terms of before and after SI reduction techniques. Moreover, this study also explores how antenna isolation characteristics vary with respect to the thickness and the permittivity of the substrate without any SI reduction technique.
Performance evaluation and state recognition method based on non‐parametric estimation algorithm for photovoltaic arrays
Authors: Li Jiaqi , Su Ying , Sun Shuang , Tang Weigui , Pan Jingna , Yue Bo , Pan Bingrong , Zhu Honglu
Published: March 2023

With the rapid development of photovoltaic (PV) power generation, state recognition of PV arrays is of great significance to its intelligent operation and maintenance. But the random fluctuation of PV power output leads to the obvious uncertainty for performance calculation of PV arrays; this paper proposes an evaluation method of PV arrays. Firstly, the performance calculation method and its distribution model were proposed by the kernel density estimation (KDE) method. Secondly, the probability density distribution (PDD) of different indicators was analyzed to determine the suitable observation indicator so as to introduce the stability indicator, from which the benchmark array was selected. Finally, the state recognition of PV arrays was achieved. The main conclusions and innovations of this paper are the stability evaluation method of PV arrays based on the non‐parameter estimation method and the effective operating state recognition method for PV arrays. The proposed method was proven to be more reliable by comparing it to the power generation ranking method (PGRM). The effectiveness was verified by comparing the statistical and real‐time distribution of the performance ratio, and the excess rate of different confidence levels and Euclidean distance were introduced to demonstrate the accuracy of the proposed state recognition method.
Spread of microplastics in the digestive systems of grouper fish (Genus epinephelus) from the Pasar Bengkulu coastal zone in Indonesia
Authors: Johan Y. , Sari Y. P. , Wibowo R. H.
Published: March 2023

Microplastics (MPs) have infected fish, crustaceans, and mollusks, among other marine fisheries products. This investigation was to determine the microplastic content of the gills, musscle, and intestines of Grouper (Genus epinephelus) in Pasar Bengkulu, Indonesia. This study was conducted in July-August 2022 with a random sample of 25 participants. At the Laboratory of Fisheries Marine Science Univerisity of Bengkulu, microplastics were analyzed. In the gills, musscle, and intestinal of Grouper Fish (Genus epinephelus), researchers discovered three types of microplastics, including fiber, film, and fragments, with a total abundance of 3.60 particles per individual. Transparent, black, and yellow were the hues discovered. Black predominated the color palette of the microplastic. 40.32μm - 675.31μm was the range of microplastic size. The FTIR analysis identifies the polymer as Polyethylenimine, Epichlorohydrin-Modified, 17 Wt% Solution In Water.
Estimation of aboveground carbon stock using the 8 operation land imagery in Lemo Nakai community forest, Indonesia
Authors: Limbong A.G. , Sulistyo B. , Barchia M.F.
Published: March 2023

Estimation of aboveground carbon stock on stands vegetation, especially in community forests in Indonesia has become an urgent issue in the effort to calculate, monitor, manage, and evaluate carbon stocks. The study aims to test the accuracy of the estimated model of aboveground carbon stocks, to ascertain the total carbon stock, and to map the spatial distribution of carbon stocks on stands vegetation in Lemo Nakai community forest lying on 3°25’59,588” - 3 27’57,982” alt. and 102°19’25,108” - 102°22’23,416” long., covering 1,053. 53 ha. The study was conducted from February to June 2022 at Baturaja Village, North Bengkulu District. Forest structure grouped classified into three classes; dense, medium and sparse stand using stratified sampling plots systematically spread out at the forest studied forest area. Above-ground biomass and carbon stock of the forest stand were estimated using allometric models. Spatial data collected from Landsat 8 OLI (operational land imager) were used to produce land-use maps of the Lemo Nakai community forest to estimate the total carbon stock, obtained from the United State Geological Survey (USGS, 2021). The result showed that the dense-, medium-, and sparse forest structure covered about 753,69 ha, 3232,41ha, and 32,49 ha, respectively. Above-ground biomass of the Lemo Nakai community forest was estimated at the dense-, medium-, and sparse structures were, respectively 389.74 tons ha-1, 278.88 tons ha-1, and 149.28 tons ha-1 with carbon stock at 179.40 tons ha-1, 128.29 tons ha-1, and 68.67 tons ha-1, respectively. Furthermore, estimated CO2eq absorption at the dense-, medium-, and sparse forest structure, respectively 657.80 tons ha-1, 470.58 tons ha-1, and 26.98 tons ha-1.