bluuebunny/crossref_metadata_2025 huggingface dataset:
Efeito de Idade e Escolaridade no Instrumento de Avaliação Neuropsicológica Breve NEUPSILIN
Authors: Rodrigues Jaqueline de Carvalho , Muller Juliana de Lima , Esteves Cristiano , Fonseca Rochele Paz , Parente Maria Alice de Mattos Pimenta , Salles Jerusa Fumagalli de
Published: August 2018

Resumo Neste estudo, investigaram-se efeitos de idade e escolaridade e suas interações no desempenho de adultos no Instrumento de Avaliação Neuropsicológica Breve NEUPSILIN, que avalia orientação têmporo-espacial, atenção, percepção, memória, linguagem, calculias, praxias e funções executivas. Participaram 627 adultos saudáveis (19 a 90 anos), divididos em três grupos, conforme escolaridade (1 a 4, 5 a 8 e 9 anos ou mais de estudo) e em quatro grupos por idade (19 a 39, 40 a 59, 60 a 75 e 76 a 90 anos). Encontraram-se efeitos de idade e escolaridade em atenção, percepção, memória (de trabalho, verbal episódica, semântica, visual e prospectiva), linguagem oral e escrita, praxias e funções executivas. Interações entre idade e escolaridade foram encontradas em atenção, memória verbal, linguagem oral e escrita. Os resultados destacam que o envelhecimento e a escolaridade impactam de forma heterogênea nas funções cognitivas, assim como os testes neuropsicológicos brasileiros devem sempre considerar a influência dessas variáveis para produzir seus dados normativos.
Effectiveness of nursing intervention for increasing hope in patients with cancer: a meta-analysis
Authors: Li Ping , Guo Yu-Jie , Tang Qing , Yang Lei
Published: August 2018

ABSTRACT Objective: to evaluate the efficacy of nursing interventions to increase the level of hope in cancer patients, in a meta-analysis. Methods: electronic databases were searched. Two of the authors independently extracted data from the eligible studies, and Stata 13.0 software was used to pool the data. Results: nine randomized controlled trials were included, and methodological quality of each randomized controlled trial (RCT) was evaluated using Cochrane handbook recommendations. A random effects model was used to combine results from eligible studies. The pooled results using the fixed effects model showed that scores to first effects increase significantly after the use of nursing intervention between the groups. Heterogeneity was observed among the studies for posttest (df = 8, P = 0.000; I2 =76.1 %). The results indicated significant heterogeneity across the nine selected studies. The test for heterogeneity showed no homogeneity among studies for follow-up (df = 8, P = 0.328; I2 = 12.9 %), and there was no statistical significance. Conclusion: the current evidence suggests that nursing intervention has a positive effect on hope in cancer patients. However, more large-scale and high-quality randomized controlled trials are needed to confirm these results.
Syphilis in during pregnancy: association of maternal and perinatal characteristics in a region of southern Brazil
Authors: Padovani Camila , Oliveira Rosana Rosseto de , Pelloso Sandra Marisa
Published: August 2018

ABSTRACT Objective: To analyze the prevalence of syphilis in during pregnancy and its association with socioeconomic characteristics, reproductive history, prenatal and labor care, and newborn characteristics. Method: A retrospective, cross-sectional study based on gestational and congenital syphilis reports. A (records) linkage was performed in the Brazilian databases: “Information System for Notifiable Diseases” (Sistema de Informação de Agravos de Notificação - SINAN); “Live Births Information System” (Sistema de Informação sobre Nascidos Vivos - SINASC); and “Mortality Information System” (Sistema de Informação sobre Mortalidade - SIM). Results: The prevalence of gestational syphilis was 0.57%. The following associations of syphilis in pregnancy were found: non-white skin color/ethnicity (PR=4.6, CI=3.62-5.76); low educational level (PR=15.4; CI=12.60-18.86); and absence of prenatal care (PR=7.4, CI=3.68-14.9). The perinatal outcomes associated with gestational syphilis were prematurity (PR=1.6 CI=1.17-2.21) and low birth weight (PR=1.6; CI=1.14-2.28). Two deaths from congenital syphilis, one death from another cause and five stillbirths were reported. Conclusion: The results signify a long way until reaching the World Health Organization’s goal of eradicating congenital syphilis.
Patient safety in nursing care during medication administration
Authors: Oliveira Júlian Katrin Albuquerque de , Llapa-Rodriguez Eliana Ofélia , Lobo Iza Maria Fraga , Silva Luciana de Santana Lôbo , Godoy Simone de , Silva Gilvan Gomes da
Published: August 2018

ABSTRACT Objective: to evaluate the conformity of care practices of the nursing team during the administration of drugs through central vascular catheter. Method: a descriptive, prospective, observational study conducted in an Intensive Care Unit. The non-probabilistic intentional sample consisted of 3402 observations of drug administrations in patients with central vascular catheters. The previously validated collection instrument was constructed based on the Guideline for Prevention of Intravascular catheter-related infections. Data was collected through direct observations of nursing practices performed by the nursing team. The analysis used analytical, descriptive and inferential statistics (Chi-square test and Fisher’s exact test). Results: a total of 3402 procedures of drug administrations were observed. Female nursing technicians performed the highest number of actions. In none of the procedures did the professional perform all necessary actions. 0.2% of drug administrations were preceded by hand hygiene and 1.3% by disinfection of the multidose vial, ampoule or injectors. Conclusion: the practice evaluated was classified as undesirable. Failure to achieve the desired conformity was probably due to the low adherence of professionals to the practice of hand hygiene and disinfection of materials, injectors and connectors.
The effect of therapeutic listening on anxiety and fear among surgical patients: randomized controlled trial
Authors: Garcia Ana Cláudia Mesquita , Simão-Miranda Talita Prado , Carvalho Ana Maria Pimenta , Elias Paula Condé Lamparelli , Pereira Maria da Graça , Carvalho Emilia Campos de
Published: August 2018

ABSTRACT Objective: To investigate the effect of therapeutic listening on state anxiety and surgical fears in preoperative colorectal cancer patients. Method: A randomized controlled trial with 50 patients randomly allocated in the intervention group (therapeutic listening) (n = 25) or in the control group (n = 25). The study evaluated the changes in the variables state anxiety, surgical fears and physiological variables (salivary alpha-amylase, salivary cortisol, heart rate, respiratory rate and blood pressure). Results: In the comparison of the variables in the control and intervention groups in pre- and post-intervention, differences between the two periods for the variables cortisol (p=0.043), heart rate (p=0.034) and surgical fears (p=0.030) were found in the control group, which presented reduction in the values of these variables. Conclusion: There was no reduction in the levels of the variables state anxiety and surgical fears resulting from the therapeutic listening intervention, either through the physiological or psychological indicators. However, the contact with the researcher during data collection, without stimulus to reflect on the situation, may have generated the results of the control group. Clinical Trial Registration: NCT02455128.
Alcohol consumption/dependence and resilience in older adults with high blood pressure
Authors: Dullius Aline Alves dos Santos , Fava Silvana Maria Coelho Leite , Ribeiro Patrícia Mônica , Terra Fábio de Souza
Published: August 2018

ABSTRACT Objective: to evaluate alcohol consumption/dependence and resilience in older adults with high blood pressure and to analyze the factors associated with these variables. Method: a descriptive, cross-sectional, quantitative study developed with 300 older adult patients with high blood pressure from Family Health Strategy units in a municipality of Minas Gerais, Brazil. A semi-structured questionnaire called the Alcohol Use Disorder Identification Test and the Resilience Scale were used. Data were analyzed using the Pearson’s chi-square test, Fisher’s exact test, Cronbach’s alpha, odds ratio and logistic regression. Results: 89.3% of the interviewees were low-risk for consuming alcoholic beverages. The variables gender, age, smoking and disease duration were significantly associated with alcohol consumption/dependence. 36.7% of the people presented a low resilience. The variables family and individual monthly income, education level, physical activity and leisure had an association with resilience. No statistically significant association was observed between alcohol consumption/dependence and resilience. Conclusion: alcohol consumption and resilience can interfere with the physical and mental health of older adults with high blood pressure.
Effectiveness of an Evidence-Based Practice educational intervention with second-year nursing students
Authors: Mena-Tudela Desirée , González-Chordá Víctor Manuel , Cervera-Gasch Agueda , Maciá-Soler María Loreto , Orts-Cortés María Isabel
Published: August 2018

ABSTRACT Objectives: to evaluate the effectiveness of an educational intervention on the knowledge, skills and attitudes of evidence-based practice among second-year nursing students. Method: a quasi-experimental before-and-after study. The study population consisted of 120 students enrolled in the Nursing Care in Healthcare Processes course. The educational intervention was based on theoretical and practical classes about the evidence-based practice process and the use of the critical incident technique during the clinical clerkship. Effectiveness was measured with the Evidence-Based Practice Competence Questionnaire in three paired measures using repeated-measures analysis of variance. Results: the mean scores of the Evidence-Based Practice Competence Questionnaire were 79.83 (CI 95% 78.63-81.03) for the basal measurement, 84.53 (CI 95% 83.23-85.83) for the intermediate measurement, and 84.91 (CI 95% 83.26-86.55) for the final measurement, with a statistically significant difference among the three paired measurements (p<0.001). There were statistically significant differences in Attitudes (p = 0.034) and Knowledge (p <0.001) but not in Skills (p = 0.137). Conclusion: this educational intervention based on theoretical and practical classes about the evidence-based practice process and the use of the critical incident technique during the clinical clerkship enhances evidence-based practice competence among second-year nursing degree students.
Moenkhausia lepidura (Kner, 1858) (Characiformes, Characidae): osteology and relationships
Authors: Darlim Gustavo , Marinho Manoela M. F.
Published: August 2018

Abstract Cladistic analysis of fishes are mostly based on osteological studies. Phylogenetic relationships within the family Characidae are poorly known in part due to the lack of anatomical studies of its members, including osteology. The present contribution aims to offer a detailed description of all bony complexes of Moenkhausia lepidura. Two remarkable morphological conditions present in the species are discussed: a bony lamella on the proximal portion of the ribs and a basal expansion of the gill rakers. A morphological survey of several species of Characidae along with available phylogenetic information of the family indicates the putative relationships of Moenkhausia lepidura with other small characids presenting bony lamella on ribs and a dark mark on the caudal fin.
Scientific production on falls and deaths among elderly persons: a bibliometric analysis
Authors: Wingerter Denise Guerra , Azevedo Ulicélia Nascimento de , Marcaccini Andrea Márcia , Alves Maria do Socorro Costa Feitosa , Ferreira Maria Ângela Fernandes , Moura Luana Kelle Batista
Published: August 2018

Abstract Objective: To map international scientific production on falls and deaths among the elderly. Method: A bibliometric study of academic papers was carried out in the ISI Web of Knowledge/Web of ScienceTM. The search terms "elderly*", "fall*" and "death*" were used for studies between 1990 and 2016. Articles from events or those still in the editing process and studies in the form of "conference proceedings", "editorial material" and "letters" were excluded, with only finished studies and complete "articles" and "reviews" considered. Results: After applying the refinement filters, 668 articles were identified during the 26 year evaluation period, published in 364 different journals indexed to the database in question. These were written by 2,958 authors with links to 1131 research institutions located in 63 countries. The articles included 22,093 references, with an average of approximately 33 references per study. Conclusion: The articles on falls and deaths among the elderly emphasize the need for more specific studies on the subject and its potential for exploration in future research. This study revealed the need for this issue to be discussed in the training of health professionals, as it represents an opportunity to deconstruct and reconstruct concepts and values that are established throughout the life of individuals, such as care related to the avoidability of falls, to improve the quality of life of this population.
Satisfaction with family relations and support according to elderly persons caring for elderly relatives
Authors: Lins Ana Elizabeth dos Santos , Rosas Carola , Neri Anita Liberalesso
Published: August 2018

Abstract Objective: The aim of the presentstudy was to investigate the associations between the satisfaction of family caregivers and family relations; sociodemographic variables; the type and direction, sufficiency and burden of family support, and the number of social partners involved. Method: A total of 148 caregivers of elderly relatives who were physically and cognitively dependent were recruited from medical clinics and home care services in cities in the state of São Paulo and invited to respond to a questionnaire about family support, and to a scale of satisfaction with family relationships with reference to adaptation, partnership, growth, affection and resolutive capacity. The chi-squared and Fisher's exact tests were used to compare frequencies for the scores of the two satisfaction levels (low and intermediate, and high). To analyze the relationship between high levels of satisfaction and other variables, univariate and hierarchical logistic regression analysis was used. Results: High levels of satisfaction were related to the reciprocity and suffiency of received emotional support, and absence of burden associated to giving support. The adequacy of emotional support was most strongly associated with high levels of satisfaction with family relationships. Conclusion: For the satisfaction of caregivers of elderly persons with family functioning, quality of support is better than quantity, reciprocity is more important than unidirectionality and emotional is the most important type of support.
EFETIVIDADE DE PROGRAMAS DE INTERVENÇÃO PARA OBESIDADE COM BASE EM ORIENTAÇÕES PARA ESCOLARES ADOLESCENTES: REVISÃO SISTEMÁTICA
Authors: Wolf Vaneza Lira Waldow , Samur-San-Martin Juan Eduardo , Sousa Suzy Ferreira de , Santos Hemerson Dinis Oliveira , Folmann Augusto Gerhart , Ribeiro Roberto Régis , Guerra-Júnior Gil
Published: August 2018

RESUMO Objetivo: Verificar a efetividade de intervenções educacionais baseadas na orientação sobre atividade física e nutrição em escolares. Fonte de dados: Foi realizada busca sistemática em quatro bancos e bases de dados eletrônicos, com artigos publicados entre outubro de 2007 e janeiro de 2017 que abordaram a realização de intervenções educacionais com ênfase em educação nutricional e atividade física ou exercício físico em escolares com idades entre 10 e 19 anos. Síntese dos dados: Foram selecionados 12 artigos para esta revisão. Desses estudos, quatro incluíram a intervenção educacional; quatro associaram intervenções educacionais à inclusão de alimentos saudáveis e atividade física; dois estudos relacionaram as orientações e a atividade física; e, por fim, dois ligaram as orientações com o consumo de alimentos saudáveis. Conclusões: As intervenções baseadas na orientação de atividade física e/ou nutrição foram eficientes, com resultados superiores nos estudos que associaram a prática de atividade física à orientação. Entretanto, observou-se a necessidade da realização de novos estudos que abordem as intervenções educacionais em escolares.
The specific impact of uremic toxins upon cognitive domains: a review
Authors: Franco Álvaro de Oliveira , Starosta Rodrigo Tzovenos , Roriz-Cruz Matheus
Published: August 2018

ABSTRACT One of the mechanisms proposed for chronic kidney disease (CKD)-related cognitive impairment is the accumulation of uremic toxins due to the deterioration of the renal clearance function. Cognition can be categorized into five major domains according to its information processing functions: memory, attention, language, visual-spatial, and executive. We performed a review using the terms 'uric acid', 'indoxyl sulfate', 'p-cresyl sulfate', 'homocysteine', 'interleukins' and 'parathyroid hormone'. These are the compounds that were found to be strongly associated with cognitive impairment in CKD in the literature. The 26 selected articles point towards an association between higher levels of uric acid, homocysteine, and interleukin 6 with lower cognitive performance in executive, attentional, and memory domains. We also reviewed the hemodialysis effects on cognition. Hemodialysis seems to contribute to an amelioration of CKD-related encephalopathic dysfunction, although this improvement occurs more in some cognitive domains than in others.
Aspectos da sobrecarga e qualidade de vida de cuidadores de pacientes hospitalizados: uma análise baseada na Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF)
Authors: Peres Paulo Alberto Tayar , Buchalla Cassia Maria , Silva Soraia Micaela
Published: August 2018

Resumo Objetivo: caracterizar o perfil e a relação entre sobrecarga e qualidade de vida (QV) de cuidadores de pacientes hospitalizados de acordo com o modelo biopsicossocial da Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF). Analisar a correlação entre a sobrecarga do cuidador e o nível de dependência motora e cognitiva do paciente. Métodos: estudo transversal com 68 cuidadores de pacientes hospitalizados há 12 ou mais dias. Para avaliação da QV e da sobrecarga dos cuidadores foram utilizados, respectivamente, o Short Form Health Survey (SF-36) e a escala de Zarit (Zarit Burden Interview). Utilizou-se a Medida de Independência Funcional para caracterizar a dependência motora e cognitiva dos pacientes. Os resultados foram relacionados aos conceitos da CIF. Resultados: de acordo com os qualificadores da CIF, um comprometimento progressivo na QV dos cuidadores foi observado com o aumento da sobrecarga. Houve correlação negativa, estatisticamente significante e de fraca magnitude, entre a percepção de QV e sobrecarga. Não houve correlação entre a sobrecarga do cuidador e o nível de dependência do paciente. Conclusão: o SF-36 é capaz de analisar 13 categorias da CIF, permitindo avaliar o cuidador de forma integral, de acordo com o modelo biopsicossocial, e facilitando o uso da CIF na prática clínica.
Human papillomavirus infection and cervical cancer precursor lesions in women living by Amazon rivers: investigation of relations with markers of oxidative stress
Authors: Borges Bruna Emanuelle Sanches , Brito Elza Baia de , Fuzii Hellen Thais , Baltazar Cláudia Simone , Sá Aline Barreto , Silva Camile Irene Mota da , Santos Gleyce de Fátima Silva , Pinheiro Maria da Conceição Nascimento
Published: August 2018

ABSTRACT Objective To investigate the relation between oxidative stress markers, human papillomavirus infection and cervical cancer precursor lesions. Methods The study comprised women aged 14 to 60 years living in communities located by Amazon rivers in the state of Pará (Itaituba, Limoeiro do Ajuru and Bragança, 126, 68 and 43 women respectively). Papanicolau smears and polymerase chain reaction tests for human papillomavirus DNA detection were performed. Blood samples were collected to test malondialdehyde, total and oxidized glutathione levels. Results Malondialdehyde, total and oxidized glutathione concentrations did not differ significantly (p>0.05) between women with and without low-grade squamous intraepithelial lesions across communities. Malondialdehyde levels (8.02nmols/mL) were almost five times higher in human papillomavirus-positive compared to human papillomavirus-negative women (1.70nmols/mL) living in Itaituba (statistically significant difference; p<0.05). Malondialdehyde levels did not differ significantly (p>0.05) between human papillomavirus-positive and human papillomavirus-negative women living in remaining communities. Significant (p<0.05) differences in total glutathione levels between human papillomavirus-positive and human papillomavirus-negative women (8.20μg/mL and 1.47μg/mL, respectively) were limited to those living in Bragança. Conclusion Malondialdehyde and total glutathione levels were significantly associated with human papillomavirus infection. However, lack of similar associations with squamous lesions suggest oxidative stress alone does not explain correlations with cervical carcinogenesis. Other factors may therefore be involved.
Exploiting the non-medical value of waste expired aminophylline for lithium ion battery anode
Authors: Dai Zhipeng , Hou Hongying , Liu Xianxi , Yao Yuan , Yu Chengyi , Li Dongdong
Published: August 2018

Expired medicines in the environment may cause the pollution and resource waste if they are not reasonably recycled. Therefore, it is very instructive to exploit the non-medical values of expired medicines. Herein, such an attempt to recycle expired aminophylline was made as the anode active material of lithium ion batteries (LIBs) for the first time. The microstructure and chemical element component of the expired aminophylline were confirmed by using the methods of scanning electron microscopy, energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. Furthermore, the feasibility of using an expired-aminophylline-based anode in LIBs was evaluated by galvanostatic charge/discharge and cyclic voltammetry. To be satisfactory, the reversible specific discharge capacities of expired-aminophylline-based anode were maintained at 268·8 mAh/g at 50 mA/g for 200 cycles and 140 mAh/g even at 500 mA/g for 1000 cycles. In addition, after coupling with a commercial lithium cobalt (III) oxide (LiCoO2) cathode, the resultant full cell also delivered 130 mAh/g at the 100th cycle at 100 mA/g. These satisfactory results may not only pave a way for the reasonable exploitation of the non-medical values of expired medicines but also offer good inspiration and strategy to develop sustainable energy and circular economy.
Irreversible electroporation for locally advanced pancreatic cancer
Authors: Astakhov D. A. , Panchenkov D. N. , Ivanov Yu. V. , Shablovsky O. R. , Kedrova A. G. , Soloviev N. A. , Nechunayev A. A. , Zlobin A. I. , Lebedev D. P.
Published: August 2018

Aim. To assess overall survival and recurrence-free period in patients with locally advanced pancreatic cancer who underwent irreversible electroporation of the tumor in combination with chemotherapy. Matherials and methods. It was performed a prospective analysis of overall survival in 23 patients who underwent irreversible electroporation of unresectable pancreatic cancer for the period from May 2012 to March 2017. Control group consisted of 35 patients with pancreatic cancer stage III who received standard chemotherapy alone. Results. Mean age of patients was 61 years (range 45–80). All procedures were successful. Fifteen patients had pancreatic head cancer, 8 – cancer of pancreatic body. Preoperative chemotherapy has been applied in 20 (86.9%) patients for 4 months prior to surgery on the average. Seventeen (73%) patients underwent chemotherapy after electroporation procedure. 90-day mortality was 4.3% (n = 1) in electroporation group. Surgery was followed by improved local recurrence-free survival (12 and 6 months, respectively, p = 0.01) and distant recurrence-free survival (15 and 8 months, respectively, p = 0.03). Overall survival was 18 and 11 months, respectively (p = 0.03). Conclusion. Irreversible electroporation of locally advanced pancreatic cancer is safe. Four-month chemotherapy followed by surgical procedure is associated with good local response and better overall survival compared with chemotherapy alone. These data will be validated in further multicenter study.
Buckling up the One Belt One Road (OBOR) Initiative: Intentions of China and Ramifications for India
Authors: Sharma S P , Singh Rohit
Published: August 2018

One Belt One Road (OBOR) is essentially a Chinese initiative to move up the value chain and to deal with its problems of overproduction of cement, steel and other products. It wants to shed its image as a nation producing cheap products and wants to instead compete with the US, Europe, Japan and Taiwan as a nation, which produces quality goods. Hence it wants to shift its production lines to cheaper countries on the OBOR route to deal with rising wages within its own country. This paper has made an attempt to throw light on the Chinese OBOR project by explaining its salient features. It then goes on to briefly describing as to what the OBOR project means for India. In it, it deals with the perceptions of countries vital to China, viz. Pakistan and China. It then goes on to discuss about the ways and means by which India is and can counter OBOR in the future including India’s measures taken in cooperation with various nations and partners. Finally, the paper concludes by laying down recommendation on what would be the best way for India to tackle OBOR and at the same time live the Indian dream and in fact even make the world to do the same.
Blue Ocean Strategy: A Review of Literature
Authors: Chadarava Piyush D.
Published: August 2018

The market dynamics are changing abruptly due to the integration of technology and another macroeconomic factor into business. The organization which is considered as a market leader may also be investing enormous funds to stay competitive. The intent was not so convincing, because investing continuously to stay competitive is not a valid solution. The concept Blue Ocean Strategy was derived in 2005 and adds value by redefining the business boundaries. It highlights the importance of reconstruction of market boundaries which make competition irrelevant. The theory sounds exciting and selects a research topic to understand its possible way of integration in the current business process. The study of literature brings an understanding of how the different framework and tools can be applied in current business, to come out from competition and sail in an uncontested market. The review brings out an understanding of two exciting concepts of Blue Ocean Strategy, i.e., how to study factors of competition, and value innovation which is the cornerstone of Blue Ocean Strategy.
ISOLATION OF PHYTOPATHOGENIC FUNGI v1
Authors: Perez-Brito Daisy
Published: August 2018

To control a disease it is essential to know its causal agent. A correct diagnosis provides a considerable amount of basic information to select correct control methods. An accurate diagnosis always starts with a representative sample of the damaged tissue, from which a portion is taken, to isolate the causal agent. In the case of phytopathogenic fungi, there are several isolation methods, depending on the tissue or substrate in which they are found. This protocol describes the isolation and purification of phytopathogenic fungi from leaves and fruits of different tropical crops.
Evaluation of cardiovascular risk factors in women with left breast cancer of middle-aged and elderly age at the stage of chemotherapy and radiotherapy
Authors: Vologdina I V , Zhabina R M , Poroshina E G , Stanzhevsky A A , Savelieva A V , Krasilnikova L A , Maslyukova E A
Published: August 2018

The study was conducted to identify risk factors for cardiovascular complications in 38 women with HER2neu negative left breast cancer without severe cardiovascular pathology, related both to the clinical features of the patients and the treatmenbeing performed. Patients after radical mastectomy were hospitalized for chemotherapy (doxorubicin in a cumulative dose not exceeding 360 mg/m2) and 3D conformal radiation therapy on the left breast breast of chest radiation doses 39 Gy (equivalent to 48 Gy of normal functioning). Separation into groups was carried out depending on the age: from 20 to 59 years - 20 patients, from 60 to 74 years - 18 patients. It was revealed that the risk of cardiovascular complications in the Score Scale was significantly higher in elderly patients due to age, increased systolic blood pressure and hypercholesterolemia. These patients showed higher rates of BMI and abdominal obesity. The study of psychosocial factors has shown great importance of the transferred stress in the past. The patients of the second group showed high personal anxiety (55.4 ± 3.4, 95% CI 49,6-56,4). In 70% of middle-aged patients and 89% of elderly patients after chemotherapy and radiotherapy cardiotoxicity in the form of cardiac insufficiency of systolic and diastolic dysfunction and asymptomatic cardiac arrhythmias was revealed. (For citation: Vologdina IV, Zhabina RM, Poroshina EG, et al. Evaluation of cardiovascular risk factors in women with left breast cancer of middle-aged and elderly age at the stage of chemotherapy and radiotherapy. Herald of North-Western State Medical University named after I.I. Mechnikov. 2018;10(2):33-38. doi: 10.17816/mechnikov201810233-38).
Optimization of Enhanced Mobile Broadband Solution for Rural and Remote Areas: A Case Study of Banten, Indonesia
Authors: Sarah Annisa , Sung Ki Won
Published: August 2018

Penelitian ini menawarkan solusi untuk akses broadband futuristik di daerah terpencil dan pedesaan dengan pilihan: optimasi LTE; dan perkembangan jaringan pita lebar yang diasumsikan sebagai 5G. Teknologi yang digunakan pada sistem 5G masa depan ialah pemanfaatan frekuensi tinggi, UE-Specific Beamforming, dan Skema Carrier Agregation (CA). Lima klasifikasi dalam implementasi jaringan futuristik: Skenario 1, Single Carrier (SC) LTE 1,8 GHz; Skenario 2, CA LTE 1,8 GHz + 2,6 GHz; Skenario 3, SC 5G 15 GHz; Skenario 4, SC 5G 28 GHz; Skenario 5, CA LTE 1,8 GHz + 5G 15 GHz. Redaman hujan diperhitungkan demi mendapat hasil realistis. Pada wilayah Leuwidamar, Skenario 5 memiliki jumlah BS paling sedikit. Sedangkan di Panimbang, Skenario 3 dan 5 memiliki jumlah BS yang paling sedikit. Namun, jika performansi energi diperhitungkan, Skenario 3 merupakan solusi terbaik. Selanjutnya, jika kita mengimplementasikan Discontinues Transmission (DTX), Skenario 3 dapat memberi kita penghematan energi yang mengesankan, dengan masing-masing penghematan sebesar 97% dan 94% pada daerah Leuwidamar dan Panimbang. Maka, hasil studi menyarankan untuk menggunakan jaringan SC 15 GHz sebagai optimisasi jaringan prospektif masa depan di Leuwidamar dan Panimbang, menimbang tercapainya salah satu target teknis teknologi 5G, yaitu ketersediaan 50 Mbps dimana saja dan kapan saja. *****Our work compared the performance of future broadband network solutions: with Optimized LTE system; and a new enhanced Mobile Broadband (eMBB) system, in which assumed to be prospective 5G network. The proposed eMBB system implements three key-techniques: high frequency, a UE-Specific Beamforming, and Carrier Aggregation (CA). We propose five solutions: Case 1, Single Carrier (SC) LTE 1.8 GHz; Case 2, CA LTE 1.8 GHz + 2.6 GHz; Case 3, SC 5G 15 GHz; Case 4, SC 5G 28 GHz; Case 5, CA LTE 1.8 GHz + 5G 15 GHz. Rain attenuation is considered to aim realistic solution. In the remote area (Leuwidamar), the Case 5 gives the least number of BS, with only 1.6 times densification of the current network. For the rural area cases (Panimbang), it is offered by Case 3 and Case 5 with the same number of BS. However, the best solution in terms of energy performance for both areas is Case 3. With DTX implementation, Case 3 gives an impressive amount of energy saving, with 97% in Leuwidamar and 94% saving in Panimbang. Thus, provided that our assumptions about eMBB techniques are fulfilled the Single Carrier 15 GHz link network is the most efficient.
Essential Oil Composition and Larvicidal Evaluation of Platycladus orientalis against Two Mosquito Vectors, Anopheles stephensi and Culex pipiens
Authors: Sanei-Dehkordi Alireza , Gholami Sahereh , Abai Mohammad Reza , Sedaghat Mohammad Mehdi
Published: August 2018

Background: Natural plant products as larvicides could be considered as desirable alternatives to synthetic chemi­cal insecticides for vector management. This study was undertaken to assess the mosquito larvicide activity of the essential oil from fresh leaves of Platycladus orientalis against two medically important species of mosquito vec­tors.
Methods: Essential oil was extracted by hydrodistillation and analyzed with gas chromatography and mass spec­trometry (GC-MS). Fresh leaves of P. orientalis tree (500g) were collected in June 2014 from Tehran, Iran and was authenticated at the Department of Medical Entomology and Vector Control, School of Public Health, Tehran Uni­versity of Medical Sciences, Tehran, Iran.
In addition, the larvicidal potential of oil was evaluated against late-3rd or young-4th instar larvae of Anopheles stephensi and Culex pipiens under laboratory condition. The mortality counts were made after 24h and LC50 and LC90 values were calculated.
Results: Forty-six components in leaves of P. orientalis were identified. The major components were α-Pinene (20.17%), 3-Carene (14%) and Cedrol (9.51%). The LC50 values against An. stephensi and Cx. pipiens larvae were 11.67ppm and 18.60ppm after 24h, respectively.
Conclusion: Platycladus orientalis oil could be considered as a natural larvicide for mosquito larval control.
 
Keywords: Anopheles stephensi, Culex pipiens, Platycladus orientalis, Essential oil, Larvicide
Antioxidant and Larvicidal Activity of Areal Parts of Scrophularia striata against Malaria Vector Anopheles stephensi
Authors: Yousefbeyk Fatemeh , Vatandoost Hassan , Golfakhrabadi Fereshteh , Mirzaee Zahra , Abai Mohammad Reza , Amin Gholamreza , Khanavi Mahnaz
Published: August 2018

Background: Scrophularia striata is a perennial plant which is native in all parts of Iran, Turkey, and Azerbaijan. In this study, the total phenol content, antioxidant and larvicidal activities of total extract and different fractions of this plant were evaluated.
Methods: The aerial parts of S. striata were collected from Boli village, Illam Province, western Iran in Apr 2013. The total phenol content of total extract and different fractions were evaluated by Folin-Ciocalteu method. Moreover, antioxidant activity was tested by DPPH and FRAPS assays. Larvicidal activity was investigated according to stand­ard method described by WHO.
Results: Ethyl acetate fraction (EF) had the highest content of total phenol (75.9±0.06mg Gallic acid equivalent/g dry extract). Furthermore, among the tested extract, methanol-water fraction (MWF), total methanol extract (TME) and water fraction (WF) showed the highest antioxidant activity in the DPPH assay (IC50= 226.8, 283.66 and 299.4 μg.ml-1, respectively). In FRAP assay MWF and WF and TME had the highest antioxidant activities (664.4±0.002, 565.3±0.003, 519.5±0.003mmol FeII/g dry extract, respectively). Ethyl acetate fraction had maximum larvicidal activity (LC50 49.1ppm) followed by TME (LC50 64.26ppm) and hexane fraction (HF) (LC50 89.69).
Conclusion: Scrophularia striata collected from west of Iran illustrated considerable antioxidant and larvicidal ef­fects and further in vitro and in vivo experimental models for investigation would be required.
Faunistic Study of the Rodents of North Khorasan Province, North East of Iran, 2011–2013
Authors: Arzamani Kourosh , Mohammadi Zeinolabedin , Shirzadi Mohammad Reza , Alavinia Seyed Mohammad , Jafari Behruz , Darvish Jamshid
Published: August 2018

Background: Rodents are one of the most important hosts for some zoonotic diseases and also act as a reservoir of some ectoparasites and endoparasites. They cause damage to the farms and inflict public health. The aim of this study was to investigate the faunal composition of rodent in North Khorasan Province, Northeast of Iran.
Methods: The sampling was carried out between 2011 to 2013. The specimens were collected using different methods including rodent death and live traps, digging of their burrow, and hand net from 75 different sample sites.
Results: The total number of 396 specimens belonging to 22 species and six families were identified. The results illustrated the high numbers and densities of Meriones persicus (17.68%), Meriones libycus (15.15%), Nesokia indica (7.32%) and Rhombomys opimus (6.82%), as the most important reservoirs for different zoonotic diseases. Moreover, significant number of other rodent species including Mus musculus (15.66%), Apodemus witherbyi (13.89%), A. hyrcanicus (0.25%), Rattus norvegicus (1.01%), Meriones crassus (0.25%), Gerbillus nanus (0.51%), Microtus paradoxus (2.27%), M. transcaspicus (0.76%), Ellobius fuscocapillus (0.25%), Cricetulus migratorius (4.29%), Calomyscus elburzensis (4.29%), C. mystax (1.26%), Spermophilus fulvus (0.25%), Dryomys nitedula (3.54%), Allactaga elater (3.54%), Jaculus blanfordi (0.25%), Meriones zarudnyi (0.25%), M. meridianus (0.51%), and Hystrix indica as hosts for parasites and zoonotic diseases were identified.
Conclusion: The high biodiversity including at least 22 species and six families of rodents were found in North Khorasan Province, some of them were medically important species.
Türkiye’de Sıtma Mücadelesinin Önemli Tanığı: Milaslı İsmail Hakkı ve ‘Sıtma Hakkında Kimler Neler Biliyor’ Risalesi
Authors: AKPINAR Aslıhan , ÖZCAN Müesser
Published: August 2018

Amaç:
Türkiye’de sıtma mücadelesinde halkı bilgilendirmek amacıyla sıtma ve korunma
yolları konusunda yayınlar da yapılmıştır. Bu çalışmanın amacı 1925 yılında
yazılan Milaslı İsmail Hakkı’nın Malarya yani sıtma hakkında kimler neler
biliyor? başlıklı eseri perspektifinden Cumhuriyetin ilk yıllarında sıtma
mücadele önerilerini tıp tarihi açısından değerlendirmektir.Gereç ve Yöntem:
Türkiye’deki yazma eser katalogları incelenerek sıtma ile ilgili kitaplar taranmış,
sıtma mücadelesinde tarafların sorumluluklarını sade bir dille aktaran
Osmanlıca alfabeyle 1925 yılında yazılmış olan kitap Latin alfabesine
çevrilerek değerlendirilmiştir.Bulgular:
Osmanlı’da ücretsiz kinin dağıtımına başlandığı 1910 yılı ile sıtma mücadele
kanununun yayınlandığı 1926 yılları arasında çeviri kitaplar ve sıtma mücadele
komisyonu raporları da dâhil en az on adet kitap basılmıştır. Milaslı İsmail
Hakkı’nın sıtma hakkında ilk kitabı 1910, bu makalenin konusu olan ikinci
kitabı 1925 yılında yayımlanmıştır. İsmail Hakkı kitapta sıtma savaş
mücadelesinin adımlarını, köylülerin, hekimler ve uzman hekimler dâhil
aydınların ve devletin sıtma mücadelesindeki sorumluluklarını ve bunları yerine
getirmek için gerekenleri aktarır.

Sonuç: İlk
kitabını Osmanlı’da sıtma mücadelesinin, son kitabını Cumhuriyet döneminde
örgütlü sıtma mücadelesinin başında yazmış bir hekim olarak Milaslı İsmail
Hakkı Türkiye’de sıtma mücadelesinin önemli tanığıdır. Köylülerin, hekimlerin,
uzman hekimlerin, aydınların ve devletin sorumluluklarını yazdığı kitabı salgın
hastalıklarla mücadelede bütüncül bir yaklaşımı vurgulaması, halkın değerlerini
göz ardı etmeyerek ikna edici argümanlar kullanması, devlet politikalarının
belirlenmesinde ve sürecin yönetilmesinde aktif katılımcı bir hekim tutumunu
yansıtması açısından dikkate değerdir.
Erciyes Üniversitesi Tıp Fakültesi Öğretim Üyelerinin Mezuniyet Öncesi Tıp Eğitimi Hakkındaki Düşünceleri
Authors: BAYKAN Zeynep , NAÇAR Melis , POYRAZOĞLU M.hakan
Published: August 2018

Amaç: Erciyes Üniversitesi Tıp Fakültesi (ERÜTF) öğretim üyelerinin fakültemizde verilen eğitim ile düşüncelerini ortaya koymak ve programın iyileştirilmesine yönelik görüşlerini almaktır.Yöntem: Tanımlayıcı tipteki bu çalışma Aralık 2013-Şubat 2014 tarihleri arasında gerçekleştirilmiştir. Veriler anket yöntemi ile toplanmıştır. 299 öğretim üyesinden 95’i (%32) anketi doldurmuştur. Anket formlarında öğretim üyesine ait tanımlayıcı bilgiler (yaş, cinsiyet, medeni durum, çalışılan anabilim dalı), ERÜTF’ de verilen eğitimle ilgili görüşleri içeren sorular yer almıştır.Bulgular: Öğretim üyelerinin %65.2’si ERÜTF’ de verilen teorik eğitimin içeriğini yeterli bulurken, %31.5’i fazla veya çok fazla bulmakta idi. Verilen pratik eğitim programının içeriğini ise %37.0’ı az/çok az bulurken %59.7’si yeterli bulmakta idi. Öğretim üyelerinin %57.5’si ERÜTF’ ün birincil amacını “nitelikli pratisyen hekim yetiştirmek” olarak belirtmişti. Öğretim üyelerinin %60.0’ı öğrencilerin gerekli bilgi, beceri ve tutumu tamamen kazanmış olarak mezun olduğunu ifade etmişlerdir. Öğretim üyelerinin öğrencilerin yeterliliklerini değerlendirirken çok iyi/iyi olarak belirttikleri ilk üç alan “alana ait bilgi kazanımı”, “alana ait temel klinik becerileri kazanımı” ve “ekip çalışması” olmuştur. Çok kötü/ kötü olarak belirtilen ilk alan ise “bilgilerin entegrasyonu ve eleştirel düşünme”, “bilimsel literatüre ulaşma becerisi” ve “araştırma becerisi” dir. Öğretim üyelerinin ERÜTF’ de mezuniyet öncesi eğitimin kalitesini arttırmak için neler yapılabilir sorusuna verdikleri yanıtların içinde ilk üçü “öğrenci sayısı azaltılmalı”, “Eğitimin öncelikli olduğu vurgulanmalı, hissettirilmeli, yönetim eğitimi birinci sıraya almalı” ve “Pratikler arttırılmalı, standardize edilmeli” olmuştur.Sonuç: Araştırmaya katılan öğretim üyelerinin yaklaşık üçte biri mezuniyet öncesi tıp eğitiminin teorik eğitim içeriğini fazla, pratik eğitimi içeriğini az bulmaktadır. Programla ilgili yapılacak iyileştirmeler bu yönde olmalıdır.
Ergenlerde Toplumsal Cinsiyet Algılarının Sosyodemografik Özelliklere Göre Değerlendirilmesi
Authors: KANTOĞLU Aycan , YURTERİ ÇETİN Nihal , ERDOĞAN Ayten
Published: August 2018

Amaç: Bu çalışmanın amacı, yaşları 12 ile 17 arasında
değişen İstanbul’da yaşamakta olan bir grup ergenin toplumsal cinsiyet rolü algılarının cinsiyet; yaş; anne babanın eğitim durumu, ekonomik durumu, çalışma
durumu gibi bir takım sosyodemografik özellikler ile ilişkilerini analiz
etmektir. Yöntem: Toplamda 100 katılımcının bulunduğu bu çalışmanın
örneklemini Balıklı Rum Vakfı Hastanesi kliniklerine başvuran bireyler
oluşturmaktadır. Katılımcıların sosyodemografik özelliklerini değerlendirmek
adına araştırmacı tarafından oluşturulan yarı yapılandırılmış Sosyodemografik
Veri Formu, cinsiyet algılarını ve toplumsal cinsiyet rollerini değerlendirmek
adına ise “BEM Cinsiyet Rolü Envanteri” ve “Toplumsal Cinsiyet Rolleri Tutum
Ölçeği” kullanılmıştır. Bulgular: “Toplumsal Cinsiyet Rolleri Tutum Ölçeği” alt boyutları (eşitlikçi
cinsiyet rolü, kadın cinsiyet rolü, evlilikte cinsiyet rolü, geleneksel
cinsiyet rolü, erkek cinsiyet rolü) ile yaş, cinsiyet, anne baba eğitim düzeyi,
annenin çalışma durumu, ekonomik düzey değişkenleri ile anlamlı bir ilişki
bulunmuştur. “BEM Cinsiyet Rolü Envanteri” alt boyutları (feminenlik,
maskülenlik, nötr) ile de yaş, cinsiyet, anne eğitim düzeyi, annenin çalışma
durumu ve ekonomik düzey değişkenleri ile anlamlı ilişki bulunmuştur. Düşük
eğitim düzeyi ve düşük ekonomik gelire sahip ailelerin çocuklarının toplumsal
cinsiyet rollerine ilişkin daha çok “geleneksel cinsiyet rolü” algısına sahip
olduğu; annenin çalıştığı, eğitim düzeyi ve ekonomik geliri yüksek ailelerin çocuklarının
ise daha çok “eşitlikçi cinsiyet rolü” algısına sahip
olduğu saptanmıştır.           

Sonuç: Ergenlerin yaşı, cinsiyeti ve ailelerinin ekonomik durumu ve
eğitim düzeyi  gibi sosyodemografik
özellikleri ile toplumsal cinsiyet algıları arasında anlamlı ilişki bulunmuştur.
Turner Sendromlu Olgularımızın Karyotip Kompozisyonlarının Başvuru Şikayetleri ve Antropometrik Verileri ile Birlikte Değerlendirilmesi
Authors: DOGAN Mustafa , ERÖZ Recep , BOLU Semih , YÜCE Hüseyin
Published: August 2018

Turner
sendromu (TS), kadınlarda ikinci X kromozomunun kısmi veya tam kaybı ya da X
kromozomunun yapısal anomalileri sonucu oluşan ve boy kısalığı, lenfödem,
kardiyak anomaliler, primer over yetmezliği ve nörokognitif problemler gibi
klinik bulgular ile karakterize bir hastalıktır. Prevalansı 1/2000-1/2500 canlı
dişi doğum olarak ortaya konmuştur. Hastaların TS tanısı almaları geniş yaş
aralıklarında olabilmektedir. TS’lu
hastalar farklı karyotip kompozisyonları göstermekte bu da hastalarda farklı
klinik manifestasyonlara neden olmaktadır. Yaptığımız çalışmada
sitogenetik analizi sonuçlarına göre 9 hastada 45,X (%45), 1 hastada 46,X,der(X),t(X,X)(p.11.2;q22)/45,X (%5), 1 hastada 45,X/46,X,del(X)(p.11.2)
(%5), 1 hastada 45,X/47,XXX (%5), 4 hastada 45,X/46,XX (%20), 2 hastada
46,X,i(X)(q10)/45,X (%10), 1 hastada 46,X,i(X)(q10) (%5) ve 1 hastada
46,X,del(X)(p21) (%5) kromozomal kompozisyon tespit edildi.
Turner sendromlu olgularımızın karyotip kompozisyonlarını, başvuru şikayetlerini,
antropometrik verileriyle birlikte literatüre katkı amaçlı sunduk.
IMPACTO DA HIPERTENSÃO ARTERIAL NA QUALIDADE DE VIDA DE IDOSOS RESIDENTES NA ZONA RURAL
Authors: Paiva Mariana Mapelli de , Dias Flavia Aparecida , Molina Nayara Paula Fernandes Martins , Tavares Darlene Mara dos Santos
Published: August 2018

Objetivou descrever as variáveis relacionadas com a hipertensão arterial sistêmica (HAS) e comparar com os escores de qualidade de vida (QV) entre idosos com e sem HAS da zona rural de Uberaba – MG. Foram constituídos dois grupos: idosos com HAS (353) e sem HAS (353). Utilizaram-se os instrumentos: semiestruturado, World Health Organization Quality of Life – BREF (WHOQOL-BREF), World Health Organization Quality of Life Assessment for Older Persons (WHOQOL-OLD). Realizou análise descritiva e teste t-Student (p<0,05). A maioria dos idosos foi diagnosticada há menos de 10 anos, por meio de exame médico de rotina, aferiam a pressão arterial, usavam medicamento e consumiam pouco sal. Os idosos com HAS apresentaram menor escore de QV em relação aos sem HAS. São necessárias medidas que minimize os impactos que a HAS causa na QV.
ASSISTÊNCIA PRÉ-NATAL A GESTANTE COM DIAGNÓSTICO DE SÍFILIS
Authors: Suto Cleuma Sueli Santos , Silva Débora Lima da , Almeida Eliana Do Sacramento de , Costa Laura Emmanuela Lima , Evangelista Taiana Jambeiro
Published: August 2018

Objetivo: caracterizar a assistência prestada a gestante com diagnóstico de sífilis durante o pré-natal em unidades de saúde da família. Métodos: estudo transversal, por meio da análise de relatórios de sistemas de informação e questionário estruturado sobre exposição à sífilis durante a gestação, aplicados a gestantes/puérperas e enfermeiras. Resultados: identificação de seis casos de sífilis em gestante, com subnotificação importante em sistemas de informação, detecção de gestantes inadequadamente tratadas devido às dificuldades apresentados pelos profissionais no manejo clínico das sífilis no curso da gestação e, percentuais de consultas pré-natais com realização de exames básicos e teste para sífilis abaixo do preconizado pelo Ministério da Saúde. Conclusões: é notória a necessidade de capacitação/sensibilização dos profissionais, ampliação da oferta de consultas, exames e notificação da sífilis na assistência ao pré-natal