bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety and Hemostatic Effectiveness of SURGICEL® Powder (Oxidized Regenerated Cellulose) in Controlling Mild or Moderate Parenchymal or Soft-Tissue Intraoperative Bleeding
Authors: Al-Attar Nawwar , de Jonge Eric , Kocharian Richard , Ilie Bogdan , Barnett Ellie , Berrevoet Frederik
Published: January 2022

Background. Topical hemostats reduce blood loss and optimize patient outcome and health care costs. The choice of agent depends on mode of action and surgical situation. This post-market clinical study evaluated the safety and effectiveness of Surgicel®-P, a powdered form of oxidized regenerated cellulose, designed to help control mild-to-moderate bleeding on broad or raw tissue surfaces.Methods. In a prospective, single-arm, multicenter trial, adult subjects with a target bleeding site (TBS) (mild-to-moderate bleeding for which conventional hemostatic methods were impractical or ineffective) were treated with Surgicel®-P. The primary endpoint was the proportion of subjects showing hemostasis at 5 minutes after application, without re-bleeding needing other hemostatic treatment. Secondary endpoints were these proportions at 3 and 10 minutes. The investigators’ ease-of-use evaluation of Surgicel®-P was recorded via questionnaire. Safety endpoints were the incidences of re-bleeding and thromboembolic events through day 30, and serious adverse events requiring surgical intervention through month 6 with a causal (including unlikely or at least possible) relationship to Surgicel®-P. Results. In 8 centers, 103 subjects were enrolled [median(range) age 64.0(33-88) years], of which 100 completed the study. Two deaths occurred, due to causes unrelated to Surgicel®-P. Surgeries were open (53.4%) or laparoscopic/thoracoscopic (46.6%), and mostly urological (37.9%) and abdominal (32.0%); TBSs included various tissue types, with mild (69.9%) or moderate (30.1%) bleeding over a median(range) surface area of 4(0.02–72.0) cm2. The 5-minute hemostatic success rate (primary endpoint) was 87.4%; the 3- and 10-minute rates (secondary endpoints) were 77.7% and 92.2%, respectively. Subgroup analyses showed 3-, 5- and 10-minute rates of 84.7%, 93.1%, 95.8% for mild, versus 61.3%, 74.2%, 83.9% for moderate bleeding, and 80.0%, 90.9%, 96.4% for open versus 75.0%, 83.3%, 87.5% for laparoscopic/thoracoscopic procedures. Within 10 minutes, initial manual compression (27.5%) was progressively abandoned, and additional Surgicel®-P was applied to 17.4% of TBSs. Investigators reverted to suture, cautery or other topical hemostats in 6.8% of procedures. No safety signals were identified. Investigators favorably evaluated the ease of use of Surgicel®-P device. Conclusions. This post-market clinical study supports the safety and efficacy of Surgicel®-P in controlling mild-to-moderate surgical bleeding in a broad range of surgical procedures.Clinical Trial Registration number. NCT03762200, 03/12/2018
The Cognitive Impairment At Acute Stage After Intracerebral Hemorrhage
Authors: You Shoujiang , Gu Cong , Zhang Wei , Wang Jiayun , Xu Jiaping , Liu Jing , Hu Hua , Cao Yongjun
Published: January 2022

Background: We determined the frequency and factors of cognitive impairment at acute stage and investigate the prognostic effect of the cognitive function at acute stage on the delayed cognitive impairment after acute intracerebral hemorrhage (ICH). Methods: A total of 208 patients with acute ICH were enrolled from January 2017 to February 2019. Cognitive function was assessed during the acute stage and follow-up after ICH using Montreal Cognitive Assessment (MoCA) score. The significant acute stage and delayed cognitive impairment was defined as a MoCA score <20 within 1 week after hospital admission and during follow-up respectively. Results: During a mean 20 (IQC 17-23) months follow-up, 185 patients with follow-up cognitive function data. There are 89 (42.8%) and 86 (46.5%) patients had acute stage and delayed significant cognitive impairment respectively. The older age, large baseline hematoma volume, more severe ICH, and low level of education were significant associated with significant cognitive impairment at acute stage (all P＜0.009). In the multivariable logistic regression model, the low acute phase MoCA score (odds ratio [OR] 0.59; 95% confidence interval [CI] 0.48-0.71; P＜0.001) was the only one independent factor associated with delayed significant cognitive impairment after ICH. Conclusions: Near half of patients have significant cognitive impairment at acute stage after ICH, which is more frequent in the elderly, those with large baseline hematoma volume, and more severe initial neurological deficit. The acute phase MoCA score was independent increased the risk of delayed cognitive impairment.
Characteristics and in-hospital morbidity trends associated with oral cavity cancer in Brazil
Authors: Vargas Deborah Gomes de Miranda , Probst Livia Fernandes , De-Carli Alessandro Diogo , Cunha Amanda Ramos da , Zafalon Edílson José , Pereira Paulo Zárate , Tagliaferro Elaine Pereira da Silva
Published: January 2022

Objectives: To analyze epidemiological aspects, including temporal trends, of in-hospital morbidity from oral cavity cancer in Brazil.Methods: Observational study based on information from the entire Brazilian territory, where data on hospital admissions for oral cancer were analyzed, obtained from the Information System of the Brazilian Cancer Registry. For the temporal series analysis, generalized linear regression model was used with the Prais-Winsten method.Results: Of the 121,971 patients hospitalized with oral cavity cancer, 76.40% were male and 23.60% were female, resulting in a M:F ratio of 3.24:1. Regarding the anatomical region of involvement among hospitalized patients with oral cavity neoplastic lesions, there was a predominance in non- specific places in the mouth, such as the floor of the mouth, soft and hard palate, among others (32.68%), followed by lesions in the region of tongue (28.89%). In this population, the predominant age group was between the fifth (31.09%) and sixth decades of life (24.99%); men had oral cavity neoplastic lesions at an earlier age than women. In all regions of the country, the staging of cases diagnosed in the tertiary health network accredited to the José Alencar Gomes da Silva National Cancer Institute (INCA) was late, with an increased tendency for metastasis. The temporal trend of the adjusted in-hospital morbidity rates showed to be increasing in the Northeast, South and Midwest regions for the male gender. For females, they were increasing in the Northeast and South regions.Conclusions: It is concluded that the distribution of in-hospital morbidity rates for oral cavity cancer in the country is irregular, with a predominance of male patients and higher in the Southeast and South regions, and there is a trend for this rate to increase in both genders.
Studies and Research on the Development of Innovative Wine-based Products
Authors: Boeriu Adriana , Lupu Mirabela , Canja Cristina M. , Calefariu Gavrila
Published: January 2022

Wine has been part of the history of mankind for millennia and is a very important product for the industry from an economic point of view, being considered a luxury product, which makes it susceptible to fraud and adultery. The predisposition to purchase new foods or products obtained in a non-traditional way depends largely on the individual, perception and consequently, a new approach to consumer development focused on the consumer is needed. In the current study, wine was considered as an important and healthy base for development of new and innovative products – jelly and jellybean. By valorizing the properties of several ingredients – anise, cinnamon, cloves, lime and Psyllium husk the obtained products were improved considering the sensory and physicochemical profile. It was noticed that the viscosity of the jelly was significantly influenced by the amount of Psyllium husk added (5g, 10g) – 152 cP for 5g added and 96.8 cP for 10g added, similar results being reported for jellybean – 20.4 cP for 2g added and 60.2 cP for 4g added. Also, the acidity of the products was influenced by the addition of Psyllium husk, the values varying according to the added proportion.
Fabrication of Bioartificial Pancreas Using Decellularized Rat Testicular Tissue
Authors: karimi samaneh , Khorsandi Layasadat , Ai Jafar
Published: January 2022

I. Background: Diabetes is a chronic disease that is associated with a decrease or disfunction of β-cell. In the present study, fabrication of bioartificial pancreas using MIN-6 β-cell line seeded in decellularized rat testicles (testis-ECM) was investigated. II. Methods and Results: In this experimental study, the whole body of testes were decellularized and after characterization, were seeded by MIN-6 cell line. The expression of insulin-related genes and proteins including Pdx-1, Glut2, Insulin, and Neurogenin-3 were evaluated. By using the radioimmunoassay method; insulin secretion was assessed under different concentrations of glucose. Seeded scaffolds with or without MIN-6 cells were transplanted to the rat's mesentery and their blood sugar and body weight were evaluated every three days for 28 days and analyzed with H&E staining. Histological assessments indicated the cells were completely removed after decellularization. The scaffold had no toxic impacts on the MIN-6 cells. Insulin release in response to different concentrations of glucose in 3D culture (testis-ECM) was significantly more than the traditional 2D monolayer culture. Moreover, the relative genes and proteins expression were significantly higher in the 3D culture, compared to the 2D control group. In vivo transplantation of the testis-ECM scaffolds showed appropriate positions for transplantation with angiogenesis and low infiltration of inflammatory cells. The recellularized scaffolds could drop blood sugar levels and increase the body-weight of STZ-diabetic rats.III. Conclusions: Our study clearly confirmed that ECM valuable organ scaffolds prepared by decellularization of the testicular tissue is suitable for the fabrication of bioartificial pancreas for transplantation.
Olivine family spectroscopy analysed using the Asymmetric Gaussian Method
Authors: Brown Adrian
Published: January 2022

This paper exploits the asymmetric Gaussian curve and its tangent space for the first time. We develop a new method of uncovering hidden absorption bands. We then use the asymmetrical Gaussian curve to derive a Master Equation to fit two overlapping bands. We then demonstrate the use of the asymmetric Gaussian curve to fit four overlapping Gaussian bands, and show how this is relevant to the olivine family spectral complex at 1 μm. We report which olivine endmember is easiest to fit using an asymmetric curve. The limitations of the asymmetric band fitting method and a critical assessment of three commonly used numerical minimisation methods are also provided.
Identifying The Prognostic Significance of Mitochondrial AAA Proteases YME1L1 Expression in Ovarian Cancer
Authors: Liao Wan-Ting , Chu Pei-Yi , Su Cheng-Chiung , Huang Mei-Shu , Tsui Wan-Lin , Chiu Ya-Ting , Wu Chun-Chi , Li Chia-Jung
Published: January 2022

Background:The discovery of early diagnosis and prognostic markers for ovarian cancer can significantly improve survival and reduce mortality. The role of the YME1L1 signaling axis in genetic alterations and immune infiltration of the tumor microenvironment remains unclear. Methods: Bioinformatics web resources, including GEPIA2, cBioPortal, Oncomine, Kaplan–Meier Plotter and TIMER were used to analyze the expression profile, prognostic value and immune infiltration of YME1L1.We further performed tissue microarray analysis of paraffin-embedded tissues from 60 ovarian cancer patients recorded at FIGO/TNM cancer staging. Results: Here, we use multi-omics analysis of multiple histological data to map the role of epigenetic and genetic alterations of YME1L1 in tumor immune infiltration and prognosis of cancer patients. We explored YME1L1 gene expression profiles by systematically analyzing the association of YME1L1 expression with the prognosis of ovarian cancer patients confirmed in multiple databases. High YME1L1 expression was associated with poorer overall survival and disease-free survival associated. Together, our studies suggest that YME1L1 may modulate tumor survival, immune features and contribute to tumor immune invasion, poor prognosis, and immunotherapy failure. Conclusion:Our findings may have clinical implications for the design of treatment strategies, prognosis assessment and follow-up management of patients receiving immunotherapy in a variety of cancers.
Synergetic Modulation of Plant Cadmium Tolerance via MYB75-mediated ROS Homeostasis and Transcriptional Regulation
Authors: Zheng Ting , Yang Feng , Zhang Dawei
Published: January 2022

Cadmium (Cd) is a heavy metal with biological toxicity, which can be detoxified through chelation and compartmentation in plants. Transcriptional regulation mediates plant Cd tolerance by modulating these processes. However, the mechanism remains to be studied. Our results showed that a previously unknown function of MYB75 transcription factor in the regulation of Cd tolerance. Cd exposure stimulates anthocyanin accumulation by raising MYB75 expression. Enhanced Cd tolerance was observed in the MYB75-overexpressing plants, whereas increased Cd sensitivity was found in the MYB75 loss-of-function mutants. Under Cd stress conditions, lower reactive oxygen species (ROS) levels were detected in MYB75-overexpressing plants than in wild type plants. In contrast, higher ROS levels were found in MYB75 loss-of-function mutants. Overexpression of MYB75 were associated with increased glutathione (GSH) and phytochelatin (PC) content by anthocyanin-mediated ROS homeostasis. Furthermore, the expression of Cd stress-related gene including ACBP2 and ABCC2 was elevated in MYB75-overexpressing plants, and this upregulation was mediated through the mechanism by which MYB75 directly bind to the promoter of ACBP2 and ABCC2. Our findings reveal an important role for MYB75 in regulation of plant Cd tolerance via anthocyanin-mediated ROS homeostasis and PC content, and through upregulation of Cd stress-related gene at transcriptional level.
Fine mapping of the tiller inhibition gene TIN5 in Triticum urartu
Authors: Si Yaoqi , Lu Qiao , Tian Shuiquan , Niu Jianqing , Cui Man , Liu Xiaolin , Gao Qiang , Shi Xiaoli , Ling Hong-Qing , Zheng Shusong
Published: January 2022

Grain yield in wheat (Triticum aestivum L.) is a polygenic trait representing many developmental processes and their interactions with environment. Among them, tillering capacity is an important agronomic trait for plant architecture and grain yield, but the genetic basis of tiller formation in wheat remains largely unknown. In this study, we identified a tiller inhibition mutant (tin5) from ethyl methane sulfonate (EMS) treated G1812 (Triticum urartu Thumanjan ex Gandilyan). A mapping population was constructed with tin5/G3146. Based on the sequence differences between G1812 and G3146, large InDels (≧5 bp) were selected and verified, and a skeleton physical map was constructed with genome-wide 168 polymorphic InDel markers. Genetic analysis revealed that the low-tiller phenotype was controlled by a single recessive locus, which we named TIN5. This locus was mapped to a 2.1-Mb region that contained 24 annotated genes in chromosome Tu7. Among these annotated genes, 16 genes expressed at the seedling stage, but only TuG1812G0700004539 showed a non-synonymous polymorphism between tin5 and WT. Our finding will facilitate its map-based cloning and pave the way for an in-depth analysis of the underlying genetic basis of tillering formation and regulation patterns.
Time-restricted feeding increases fat oxidation rate but not affect postprandial lipemia: a crossover trial
Authors: Chiu Chih-Hui , Chen Che-Hsiu , Wu Min-Huan , Hsieh Yu-Chen , Lin Zong-Yan , Chen Bo-Wei
Published: January 2022

Background: Studies have revealed that time-restricted feeding affects the fat oxidation rate; however, its effects on the fat oxidation rate and hyperlipidemia following high-fat meals are unclear. This study investigated the effects of 5-day time-restricted feeding on the fat oxidation rate and postprandial lipemia following high fat meals. Methods: In this random crossover experimental study, eight healthy male adults were included each in the 5-day time-restricted feeding trial and the control trial. The meals of the time-restricted feeding trial were provided at 12:00, 16:00, and 20:00. The meals of the control trial were provided at 08:00, 14:00, and 20:00. The contents of the meals of both trials were the same, and the calories of the meals met the 24-hour energy requirement of the participants. After 5 days of the intervention, the participants consumed high-fat meals on the sixth day, and their physiological changes were determined. Results: The fasting fat oxidation rate (p<0.001) and postprandial fat oxidation rate (p=0.019) of the time-restricted feeding trial were significantly higher than those of the control trial. The 24-hour energy consumption and postprandial triglyceride, blood glucose, insulin, glycerol, and free fatty acid concentrations of the two trials showed no significant differences (p>0.05). Conclusion: The results revealed that 5 days of time-restricted feeding effectively increased the fasting and postprandial fat oxidation rate, but it did not affect postprandial lipemia.
Titanium Dioxide Nano-Particles Recovered From Red Sediment Placer Low Graded Ilmenite With Microwave Heating Followed by Sds Solution
Authors: SRIK SATYA , Rao Raghupatruni
Published: January 2022

Microwave is source of environmentally heating of minerals. The present paper deals about the recovery of titania in form of slag with microwave reduction of oxidized ilmenite. This paper was further investigated for the recovery of upgraded titania from microwave heat treatment of titania obtained from ilmenite. The results show upgraded titania contain a very high graded TiO2 components with less amounts of alkaline-earth materials and other impurities as compared to titanium obtained from ilmenite. The upgraded titania was produced the crack and development of pores in the sample surface. An attempt was also made to prepare nano-titania material with suitable leaching and microwave heating. The results with TEM analysis and XRD analysis show the formation of nano titanium dioxide particles. The titanium dioxide nano materials can widely be used in pharmacy and medical industries, paints and coatings industries,, catalysts, semiconductors, optoelectronics industries and others including water filters areas.
Haldane’s asymptotics for slightly supercritical processes
Authors:   , Boenkost Florin
Published: January 2022

Analysing survival or fixation probabilities for a beneficial allele is a prominent task in the field of theoretical population genetics. Haldane's asymptotics is an approximation for the fixation probability in the case of a single beneficial mutant with small selective advantage in a large population. In this thesis we analyse the interplay between genetic drift and directional selection and prove Haldane's asymptotics in different settings: For the fixation probability in Cannings models with moderate selection and for the survival probability of a slightly supercritical branching processes in a random environment. In Chapter 3 we introduce a class of Cannings models with selection that allow for a forward and backward construction. In particular, a Cannings ancestral selection process can be defined for this class of models, which counts the number of potential parents and is in sampling duality to the forward frequency process. By means of this duality the probability of fixation can be expressed through the expectation of the Cannings ancestral selection process in stationarity. A control of this expectation yields that the fixation probability fulfils Haldane's asymptotics in a regime of moderately weak selection (Thm. 8). In Chapter 4 we study the fixation probability of Cannings models in a regime of moderately strong selection. Here couplings of the frequency process of beneficial individuals with slightly supercritical Galton-Watson processes imply that the fixation probability is given by Haldane's asymptotics (Thm. 9). Lastly, in Chapter 5 we consider slightly supercritical branching processes in an independent and identically distributed random environment and study the probability of survival as the number of expected offspring tends from above to one. We show that only if variance and expectation of the random offspring mean are of the same order the random environment has a non-trivial influence on the probability of survival, which results in a modification of Haldane's asymptotics. Out of the critical parameter regime the population goes extinct or survives with a probability that fulfils Haldane's asymptotics (Thm. 10). The proof establishes an expression for the survival probability in terms of the shape function of the random offspring generating functions. This expression exhibits similarities to perpetuities known from a financial context. Consequently, we prove a limiting theorem for perpetuities with vanishing interest rates (Thm. 11).
Sustainable development of regions: Modeling the management of economic security of innovative entrepreneurship
Authors:   National Scientific Center «Institute of Agrarian Economics», Kyiv, Ukraine, et al. Khodakivska
Published: January 2022

The purpose of this study is to develop a methodology for assessing the level of economic security of innovative enterprises based on the use of taxonomic analysis of the main indicators of their institutional support for the optimal organization of management and forecasting the economic development of the regions of their operation. The method proposed in the article consists in assessing the system of indicators of institutional support for innovative entrepreneurship within the framework of the Institute of Human Capital, the Institute of Financial and Credit Component, the Institute for the Implementation of Innovations in Industry, the Institute of Export Activities, the Institute of Intellectual Property, the Institute of Infrastructure Support, the Institute of Regulatory and Legal Support, the Institute of Public-Private Partnership and Mediation, the Institute of Information Support. The advantage of this technique over the methods for assessing economic security proposed in other scientific works is that the summary assessment indicator is universal and its interpretation makes it possible to identify the relationship between the main integrated indicators for all regions of the studied country, taking into account the unevenness of their economic development, as well as to analyze the question of the causal nature of the transformation of the institutional environment and its consequent. The practical significance of systematized indicators of institutional support, influencing the modeling of economic security management of innovative entrepreneurship, is that they can be used in forecasting the economic development of regions of the country and developing appropriate measures to regulate this process.
Evaluation of the First Year(s) of Physicians Collaboration on an Interdisciplinary Electronic Consultation Platform in the Netherlands: Mixed Methods Observational Study
Authors: Sanavro Sanne M , van der Worp Henk , Jansen Danielle , Koning Paul , Blanker Marco H ,   Prisma Platform Study Group
Published: January 2022

Background

Complexity of health problems and aging of the population create an ongoing burden on the health care system with the general practitioner (GP) being the gatekeeper in primary care. In GPs daily practice, collaboration with specialists and exchange of knowledge from the secondary care play a crucial role in this system. Communication between primary and secondary care has shortcomings for health care workers that want to practice sustainable patient-centered health care. Therefore, a new digital interactive platform was developed: Prisma.

Objective

This study aims to describe the development of a digital consultation platform (Prisma) to connect GPs with hospital specialists via the Siilo application and to evaluate the first year of use, including consultations, topic diversity, and number of participating physicians.

Methods

We conducted a mixed methods observational study, analyzing qualitative and quantitative data for cases posted on the platform between June 2018 and May 2020. Any GP can post questions to an interdisciplinary group of secondary care specialists, with the platform designed to facilitate discussion and knowledge exchange for all users.

Results

In total, 3674 cases were posted by 424 GPs across 16 specialisms. Most questions and answers concerned diagnosis, nonmedical treatment, and medication. Mean response time was 76 minutes (range 44-252). An average of 3 users engaged with each case (up to 7 specialists). Almost half of the internal medicine cases received responses from at least two specialisms in secondary care, contrasting with about one-fifth for dermatology. Of note, the growth in consultations was steepest for dermatology.

Conclusions

Digital consultations offer the possibility for GPs to receive quick responses when seeking advice. The interdisciplinary approach of Prisma creates opportunities for digital patient-centered networking.
Management Information System for Milling Section at Sugar Factory
Authors: Yadav Rohit Suresh
Published: January 2022

Abstract: One of the most important goals in any organization is increasing work force productivity Information systems, Systems are the responsibility of their data and their processing of information within the organization and managers to provide information on important economic decisions making. Hutatma Sahakari Sakhar Karakhana. Ltd. is well known sugar industry having 5000 tccpd to 6000 tccpd capability along with new constructed new ethanol plant and using different facility in this factory such as leveller, fibrizor, kicker, TRPS rolling mill, elevator, boiler, pan and centrifuge. Management Information System (MIS) in increasing human resource productivity. Savings in labor, increased consumer surplus, improved customer service quality, improved organizational efficiency, quicker response to customers, deeper knowledge and understanding of customers. The purpose of this Project is to surveying the effect of management information system of productivity and its elements such as work speed, work cost, work accuracy (efficiency) and supervision and control status improvement, planning status improvement and make decision status improvement (effectiveness) of overall machine, man and material to improve performance of all over machinery, information systems.
RECENT ADVANCES IN POLYMERIC HYDROGEL SCAFFOLDS FOR SKIN TISSUE ENGINEERING AND REGENERATIVE MEDICINE
Authors: Uppuluri Arjun
Published: January 2022

Lack of self-healing capability in skin tissue defects caused by various traumatic conditions often leads to a challenging situation for clinical practitioners. Although various procedures are offered in clinics, some of which effectively restores the skin tissue to some patients, none of them result in an adequate tissue repair that can withstand mechanical stresses under natural weight-bearing conditions. The ability of hydrogels to form 3D networks, which can be fine-tuned using biocompatibility and biodegradability factors, has sparked much interest in these hydrophilic polymers. A systematic overview of emerging hydrogel-based therapies for skin tissue repair is presented in the current study to address the unsolved issue of skin tissue defects and test whether such therapeutic approaches may enhance the healing process where skin tissue has been damaged.
ASSESS THE COMMUNICATION PATTERN AMONG CONSCIOUS MECHANICAL VENTILATION PATIENTS AND NURSES IN THE SELECTED INTENSIVE CARE UNIT
Authors: Neelavathi P
Published: January 2022

Conscious ventilator dependent patients often experience communication difficulties due to intubation. The study aimed to understand the conscious mechanical ventilation (MV) patients and nurses existing communication pattern in the ICU and develop the augment alternative communication method (AAC). In this quasi experimental study (pretest and posttest design), participants were enrolled using purposive sampling method and assigned to experimental (n = 10) and control (n = 10) groups from ICU based on certain determined criteria. Communication pattern assessment observational check list used to collect the data from both groups. Patients were used paper and pen as aided communication device 45 %, head nodding 95 % and hand movement using fingers 75 %. Patients primarily prefer to communicate with nurses 95% .Patients expressed pain associated in the endo tracheal (ET) tube and inability to communicate 100% and 95% respectively. Ninety percent of the patients expressed feeling of anxiety / fear of dying and feeling of afraid. The study further revealed 100% of the patients expressed trouble sleeping and feeling of discomfort, 100% wanted to know about their condition, when will ET tube be removed and when I go home. With regards to patients physical care needs, 100% expressed thirsty feeling, need to be suctioned and hungry feeling, 75% expressed their lip to be moistened. Related to nurses positive communication strategies, 90% makes eye contact, 85�ing kind and spoke slowly. With regards to negative strategies 75% of the nurses spoke too rapidly and selftalk mumbling. Nurses used yes/ no gestures 100%, head nodes 85% and AAC no were not used other than natural methods. Communication pattern assessment helps the nurses to find out and distinguish the sources of discomforts, distressed symptoms especially the domains such as psychological, physiological, spiritual, comfort needs, expectations and preparing appropriate AAC for conscious MV patients.
COPE Flowcharts and infographics – Peer review manipulation suspected during the peer review process
Authors: Editorial Article
Published: January 2022

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Aumento horizontal alveolar de maxila atrófica utilizando malha de titânio associado ao parafuso tenda e enxerto xenógeno – relato de caso
Authors: Fabiano Ronaldo Gomes , Skiba Tarcio Hiroshi Ishimine , Almeida Flavio Xavier , Milanello Luciano Luis , Faveri Marcelo
Published: January 2022

Guided bone regeneration has gained great prominence in the reconstruction of atrophic alveoli. Therefore, this study aims to report the clinical results of a bone augmentation technique associated with titanium mesh and tent screws. After a correct diagnosis, the graft procedure was performed in a 70:30 ratio of biomaterial from xenogeneic origin and autogenous bone, respectively. In this case, a titanium mesh was used concomitantly with the tent screw to improve the stability of the framework. Cone bean computed tomography radiographic analysis showed a mean horizontal gain of approximately 5 mm, without major post-surgical complications. The technique proved to be effective for horizontal gain of atrophic alveolar ridge and can be one of the treatment options for horizontal gains in anterior areas.
Bima-Drona dalam Lakon Dewa Ruci sebagai Vayu-Vata, Transformasi Prana dalam Pertunjukan Wayang
Authors: Wahyudi Aris
Published: January 2022

AbstrackRelationship of Bima and Drona in Dewa Ruci story is unique. Eventhough Drona puts Bima into danger, Bima chooses Drona as a teacher. It is because Bima has not obtained a very good spiritual knowledge about life yet since a hero is supposed to have high spiritual qualities and good prayers. The wayang tradition describes Bima as a cruel hero who is not religious, and Drona does not have good brahman qualifications, either. This leads to an assumption that their relationship must be important and meaningful. The question is what does the relationship between Bima-Drona mean, namely Bima as the learner who becomes the recipient of spiritual knowledge of welfare and Drona as his teacher? With structural mythological analysis, it can be concluded that the relationshp between Bima-Drona is an identification of Vãyu-Vãta as the transformation of prana in the Syiwapuja rituals. AbstrakBima dan Drona dalam cerita Dewa Ruci adalah hubungan yang unik. Meski Drona menjerumuskan Bima, namun Bima memilih Drona sebagai guru. Apalagi hal yang berhubungan dengan pengetahuan spiritual yang sangat baik tentang kehidupan, di mana dapat ditemukan oleh pahlawan yang memiliki kualitas spiritual yang tinggi, doa yang baik, tetapi Bima belum. Tradisi wayang memaparkan bahwa Bima adalah pahlawan yang kejam, tidak berkarakter religius dan Drona belum memiliki kualifikasi brahmana yang baik. Fenomena itu memunculkan asumsi bahwa hubungan tersebut pasti bermakna. Pertanyaannya adalah apa arti Bima-Drona, yaitu Bima sebagai penerima pengetahuan spiritual tentang kesejahteraan dan Drona sebagai gurunya? Dengan analisis mitologi struktural dapat disimpulkan bahwa Bima-Drona adalah identifikasi Vãyu-Vãta sebagai transformasi prãna dalam upacara ritual Syiwapuja.
The scientific contribution of scholars representing the Plekhanov Russian University of Economics to the accounting theory development: A historical retrospective
Authors: DAVLETSHIN Lidiya I.
Published: January 2022

Subject. This article studies the historical experience of the formation and development of the school of thought of scientists representing the Plekhanov Russian University of Economics.
Objectives. The article aims to study the theoretical foundations of the doctrines of the school of Nikolai S. Lunskii and his followers, and the tendencies of development of the scientific-based theory of balances.
Methods. For the study, I used the methods of observation, comparison, generalization, and interpretation. The works by well-known scientists in the field of accounting of the early twentieth century, such as N.S. Lunskii, A.M. Galagan, A.P. Rudanovskii, Ya.M. Gal'perin are the methodological basis of the study.
Results. The article shows that with the advent of a new theory of balances, representatives of the Moscow School began to scientifically develop and theoretically substantiate the principles of accounting, determine the main directions and scientific methods of research based on the analysis and synthesis of accounts axioms, methods of cognition and scientific ideas of authors representing the Italian, French, and German scientific schools of accounting.
Conclusions and Relevance. The scientific research findings of outstanding scientists who worked at the beginning of the 20th century played a special role in the formation and development of the school of thought of the Plekhanov Russian University of Economics. The significance of the study lies in the substantiation of the position that when further developing the theoretical foundations of accounting, it is advisable to use the scientific ideas of the authors of previous years.
Methodological approaches to the evaluation of internal control during the audit of the "Output of Products" business process productivity
Authors: MAMUSHKINA Natal'ya V.
Published: January 2022

Subject. This article deals with the issues of improving methodological approaches to the evaluation of internal control.
Objectives. The article aims to clarify the methodology for evaluating the internal control of costs for the production of livestock products, taking into account the peculiarities of agriculture and the business process Output of Products.
Methods. For the study, I used the methods of abstraction, analysis, systematization, and generalization.
Results. The article offers a developed methodological toolkit for evaluating the internal control system of an economic entity. It includes regulations for assessing the level of the client's internal control system and determining the efficiency rating. The proposed methodology is based on the point-rating system of internal control evaluation.
Conclusions and Relevance. The objectives of internal control are not limited only to checking the functioning of accounting systems and preparing accounting (financial) statements, including compliance with the requirements of regulatory enactments when committing facts of economic life of an economic entity. They are also focused on assessing the achievement of the goals of an economic entity and the effectiveness of its business processes. The results of the study can be used to develop theoretical and practical provisions of the activities of audit organizations and auditors.
Revisiting the hydropower assessment of the economically effective part of the river flow of Kabardino-Balkaria
Authors: BEKKIEV Mukhtar Yu. , KALOV Rizuan O.
Published: January 2022

Subject. This article deals with the issues related to the economic potential of hydropower engineering.
Objectives. The article aims to define the boundaries of the economically justified growth in the production of own electric energy, taking into account the high variability of the natural discharge regime of the mountain zone.
Methods. For the study, we used mathematical and analytical methods, and the method of natural analogues.
Results. Based on the analysis of the impact of the transformation of mountain landscapes on channel processes, the article determines the economically efficient part of the river flow with the highest possible accuracy, designates the most favorable control sections of watercourses, and proposes energy-technological schemes for the implementation of their properties.
Conclusions. The low economic efficiency of hydroelectric power plants’ operation in mountainous regions is due to an abnormally growing discrepancy between the phases of climate variability and the correlated water rate in the control points of rivers. Linking several hydroelectric power plants with the optimal interaction mode will increase the economic efficiency of energy output and reduce energy loss.
International experience of spatial development and key emphases for Russia
Authors: STROEV Pavel V. , MAKAR Svetlana V.
Published: January 2022

Subject. This article considers the main parameters of spatial development of the economy.
Objectives. The article aims to conduct a systems analysis of foreign experience necessary to optimize the process of shaping the national space of Russia.
Methods. For the study, we used general scientific research approaches.
Results. The article identifies and substantiates the criteria that are most acceptable for conducting a comparative analysis of countries from the perspective of spatial development. A comprehensive analysis of spatial development in China, Canada, Brazil, Australia, Finland, and Kazakhstan was carried out. The article offers recommendations for improving the practical foundations of the modern organization of the national space.
Relevance. The results of the study can be used by the authorities in the process of improving the modern organization of the national space of Russia.
Quelle responsabilité sociale de la presse? La couverture des attaques à Ottawa et à Saint-Jean-sur-Richelieu
Authors: Carignan Marie-Eve
Published: January 2022

fr. Dans cet article, l’auteure s’intéresse au contexte entourant la création des ins- tances d’autorégulation médiatique en revenant sur les fondements de la théorie de la responsabilité sociale de la presse, qui étayent les principes de base des guides déontologiques d’organismes d’encadrement des médias, dont le Conseil de presse du Québec. L’évolution des pratiques professionnelles journalistiques amène un questionne- ment sur les limites actuelles de ce type d’encadrement pour couvrir les situations de crise, alors que la société, qualifiée de « société du risque » par plusieurs auteurs, est confrontée à un nombre croissant de dangers et que le cadre de pratique amène les journalistes à couvrir davantage ce type d’événement. S’intéressant en particulier au cas des attaques survenues à Ottawa et à Saint-Jean-sur-Richelieu au Canada en octobre 2014, l’auteure met en parallèle différentes pratiques observées chez les médias canadiens avec les principaux griefs relevés dans la jurisprudence du Conseil de presse du Québec et les énoncés déontologiques du Guide de déontologie journalistique du Conseil de presse du Québec, dans le but de tracer les limites potentielles d’application des principes de l’organisme en contexte critique. Cette analyse permettra d’entamer une réflexion sur la viabilité de la théorie de la responsabilité sociale de la presse et des processus d’autorégulation médiatiques actuellement en place ainsi que sur le rapport entre liberté de presse et droits individuels (vie privée, sécurité, respect des personnes) de même qu’entre intérêt public et curiosité publique.
Peran Media Cetak Lokal Dalam Komunikasi Bencana Sebagai Pendukung Manajemen Bencana
Authors: Annapisa Muhammad
Published: January 2022

Upaya manajemen bencana alam yang terjadi di Indonesia saat ini memerlukan dukungan dari media massa dalam melakukan komunikasi kepada masyarakat. Degradasi lingkungan dan global warming menyebabkan wilayah Indonesia menjadi rawan bencana. Informasi mengenai situasi pra bencana, saat kejadian, dan pasca bencana menentukan terbentuknya keamanan dan kemampuan warga menghadapi bencana. Media cetak lokal dapat berperan sebagai early warning system dan melakukan edukasi bagi masyarakat. Konvergensi media saat ini memberikan kemudahan bagi masyarakat untuk mengakses informasi mengenai bencana penting yang dapat mendukung efisiensi manajemen bencana. Kajian ini bertujuan untuk memberikan gambaran mengenai pengemasan informasi bencana di media massa. Konsep yang digunakan sebagai dasar kajian adalah jurnalisme bencana, komunikasi risiko bencana dan manajemen bencana. Metode penelitian menggunakan studi literatur dan analisis teks framing pada media cetak yang memberitakan berita bencana, dengan pilihan kasus pada pemberitaan oleh harian pagi Rakyat Riau. Hasil dari kajian ini menunjukkan bahwa peran komunikasi bencana menentukan keberhasilan pemerintah untuk memberikan informasi bagi keamanan masyarakat dan mengatasi bencana yang terjadi. Kajian ini memberikan kontribusi bahwa optimalisasi komunikasi bencana secara terpadu penting dalam manajemen bencana, sinergi dengan pelibatan media massa dan masyarakat dalam distribusi informasi melalui pemanfaatan media.
Pelatihan Pengembangan Usaha Jamur Tiram Putih “Rumah Jamur Nando” di Pekanbaru
Authors: Agustin Hamdi , Indrastuti Sri
Published: January 2022

Rumah jamur nando tidak hanya menjadi tempat budidaya jamur tiram saja melainkan sebagai tempat wisata dan edukasi mengenai budidaya jamur tiram putih untuk menarik pengunjung. Tujuan pelatihan ini adalah untuk pengembangan usaha jamur putih“Rumah Jamur Nando” disamping itu juga dilakukan analisis kelayakan finansial usaha jamur tiram putih “Rumah Jamur Nando” di Kelurahan Sialang Sakti Kecamatan Tenayan Raya, Kota Pekanbaru Provinsi Riau yang meliputi: benefit, biaya, kriteria investasi (GVM, GI, NPV, IRR, NET B/C, PP). hasil dari pelatihan tersebut menunjukkan bahwa usaha jamur tiram putih “Rumah Jamur Nando” dapat dikembangkan dengan melakukan pengembangan usaha dengan dengan cara Meningkatkan jumlah produksi jamur putih, Meningkatkan jumlah lahan Usaha Jamur Tiram Putih “Rumah Jamur Nando” dan Melakukan pengembangan variasi jamur dan tanaman sayur lainnya.
Pelatihan Pemantapan Penguasaan Bahan Ajar IPA Terintegrasi Nilai-Nilai Al-Qur’an Pada Guru-Guru SD Kab. Indragiri Hulu
Authors: Robiah Siti , Suryanti Suryanti , Ferazona Sepita
Published: January 2022

Ilmu Pengetahuan Alam merupakan ilmu yang memiliki karakteristik berbeda dengan ilmu yang lain yakni mengandung ayat-ayat Qauniah dan ayat-ayat Qauliyah sehingga butuh skill dan bahan ajar tersendiri dalam mentransfer ilmunya. Namun demikian pelaksanaan proses pembelajaran yang dilakukan guru-guru SD IPA masih bersifat parsial dengan hanya mengutamakan target capaian ayat-ayat Qauniah semata (aspek kogitif IPA) sehingga aspek qauliyah terutama sikap islami terabaikan, disamping itu memang masih kurangnya bahan ajar IPA yang terintegrasi nilai-nilai Alqur’an yang bisa dijadikan i acuan bagi guru-guru SD. Sebagai solusi terhadap permasalahan tersebut maka guru-guru SD perlu dibekali melalui suatu pelatihan pemantapan penguasaan bahan ajar IPA terintegrasi nilai-nilai alqur’an agar dapat diaplikasikan kepada peserta didik.
Persepsi Masyarakat terhadap Bantuan Langsung Tunai (BLT) pada Masa Pandemi Covid-19
Authors: Reptiana Rofiqoh Prepti , Widiantoro Didik , Sari Wina Diana , Desvianti Erika , Arezah Ersaliya
Published: January 2022

Since the Corona Virus Disease-2019 (COVID-19) pandemic was officially declared to have entered Indonesia, in March 2020. This outbreak had an impact on the social and economic consequences of the Covid-19 pandemic which also affected the level of public welfare. This is due to the limitation of economic activity which at a macro level reduces economic growth and causes many people to lose their jobs, thereby potentially increasing the number of poor people. Based on this, the Government seeks to provide direct cash assistance for the community from the Village Fund or called BLT-Village Fund to reduce the burden on the poor due to the impact of Covid-19. BLT-Dana Desa is financial assistance sourced from the Village Fund and is intended for the poor and vulnerable who have difficulty meeting their daily needs, especially due to the Covid-19 outbreak. Village Fund Cash Direct Assistance (BLT-Village Fund) in Harapan Jaya Village, Central Bunguran District, Natuna Regency in 2020, for people who receive Village Fund Cash Direct Assistance (BLT) in Harapan Jaya Village, Bunguran Tengah District, Natuna Regency in 2020. quite a lot, namely with a total allocation of the number of people who receive as many as 225 Family Heads. The purpose of this study was to determine the perception of the recipient community towards the Direct Cash Assistance (BLT) program during the Covid-19 Pandemic in Harapan Jaya Village, Central Bunguran District, Natuna Regency. This research was conducted with descriptive qualitative methods, namely interviews and observations using purposive sampling technique. Data analysis technique using Milles and Huberman theory, namely redcing, presenting data, and concluding data. The results of this study indicate that the perceptions of the four subjects to feel the benefits of BLT are different.
Photouncaging of Carboxylic Acids from Cyanine Dyes with Near-Infrared Light
Authors: Janeková Hana , Russo Marina , Stacko Peter
Published: January 2022

Near-infrared light (NIR; 650–900 nm) as biocompatible stimulus offers unparalleled advantages in terms of availability, high precision in time and space and deep tissue penetration. The development of photocages that operate in this region represents a fundamental challenge due to low energy of the excitation light. Herein, we repurpose cyanine dyes into photocages that are available on a multigram scale in three steps and efficiently release carboxylic acids in aqueous media upon irradiation with NIR light up to 820 nm. The photouncaging process is examined using several independent techniques and we provide compulsive evidence that it proceeds via photooxidative pathway. In vitro biocompatibility of the photocages and their photoproducts is also demonstrated. In combination with modularity of the cyanine scaffold, the realization of these accessible photocages will aid fully unleashing the potential of the emerging field of NIR-photoactivation and facilitate its widespread adoption outside the photochemistry community.