bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of the World Health Organisation and International Consensus Classification of haematolymphoid tumours
Authors: Cassim Sumaiya , Nell Erica-Mari , Gantana Ethan J. , Musekwa Ernest M. , Lohlun Robert K. , Abdullah Ibtisam , Chapanduka Zivanai C.
Published: September 2024

Background: The World Health Organization has updated its classification of haematolymphoid tumours to the new 5th edition. The International Consensus Classification is another group that has developed a separate classification system with similar but conflicting approaches. This led to a debate among haematologists about which classification system is more appropriate for clinical use. This article examines and compares these contrasting and concurring classifications, and provides insight into the utility of each system.Methods: Journal articles pertaining to WHO-HAEM4R, WHO-HAEM5 and ICC were searched for using the MEDLINE database, from November 2022 to November 2023. Original research articles and reviews were selected to compile this review.Results: The classification systems share many similarities with minor name changes and subgrouping. There are few instances where diagnostic grouping differs between the classifications, which could have clinical implications regarding treatment and enrolment in clinical trials.Conclusion: There is universal agreement about the need for objective criteria for the classification of haematolymphoid tumours. As a result, there have been considerable strides in the classification with regard to morphologic, immunophenotypic, molecular and cytogenetic characterisation. It is reassuring to have a stepwise approach to diagnosis, allowing developing countries to make appropriate diagnoses.Contribution: Harmonisation is needed for a universal diagnostic system for the benefit of the patient. Both classification systems have merit and either could be adopted by individual institutions at present. The authors appeal for interim advocacy measures to assure access to the specific diagnostic investigations in poorly resourced societies, pending more permanent and sustainable access.
Evaluating the Clinico-biochemical Association between Stress and Chronic Periodontitis by Estimation of Serum Cortisol and Serum Chromogranin A Levels
Authors: Duseja Shilpa , Parikh Hiral Akshat , Duseja Sareen
Published: September 2024

Introduction:

Periodontitis is a persistent diseased condition of the oral tissues that manifests as loss of attachment. Alterations in immune, neural, endocrinal and behavioural systems caused by stressful life events may impair periodontal health. Using serum stress markers, this study was designed to investigate the link between periodontal infection and psychoneuroimmunologic variables.

Materials and Methods:

Four hundred systemically healthy patients in the age group of 20–60 years were selected and segregated into two groups, namely healthy periodontium group (200 subjects) and chronic periodontitis group (200 subjects) after recording plaque index, probing depth, gingival index and clinical attachment loss. The analysis of stress levels using the Social Readjustment Rating Scale and lifestyle evaluation using the Health Practice Index was done. Serum cortisol and serum chromogranin A (CgA) levels were recorded. Descriptive statistics and unpaired t-tests for comparing the differences in the parameters and Pearson’s correlation test for establishing the correlation between serum markers with clinical variables and stress levels were done. Multivariate analysis of covariance analysis was done to find the linear relation of periodontal and serum parameters (dependent variables) with psychological stress and lifestyle patterns (independent variables).

Results:

A poorer lifestyle and higher stress magnitude were more allied to worsened periodontal condition (P ≤ 0.05). Significantly higher (P ≤ 0.05) concentrations of serum cortisol and serum CgA levels were observed in the chronic periodontitis group.

Conclusion:

Stress shall be regarded as a probable risk factor for periodontal infection, and it should be catered to attain benefits in patients with inexplicable periodontal disease.
Higher Body Mass Index is Associated with Increased Oxidative Stress in Patients of Type 2 Diabetes Mellitus
Authors: Almeida Edelbert A. , Mehndiratta Mohit , Madhu Sri V. , Kar Rajarshi
Published: September 2024

Introduction:

Type 2 diabetes mellitus (T2DM) is closely associated with the obesity; however, certain proportion of T2DM patients is non-obese or lean (BMI < 18.5 kg/m2). Obesity has long been associated with oxidative stress; however, there are no studies available documenting levels of oxidative stress in the lean patients of T2DM. Therefore, this study was done to compare the levels of makers of oxidative stress (TL, mtDNA, TAS) and their regulators (mRNA expression of TERT, Nrf2 and Nqo1) in lean and obese patients of T2DM.

Methods:

60 newly diagnosed patients (treatment naïve) of T2DM were recruited and divided into lean (BMI < 18.5 kg/m2) and obese (BMI > 25 kg/m2) groups. Relative telomere length (T/S) and mtDNA content were estimated via real-time PCR. Serum total antioxidant status (TAS) was measured using a commercially available kit. mRNA expression of TERT, Nrf2 and Nqo1 was measured by real-time PCR.

Results:

Mean T/S and mtDNA content were lower in the obese group compared to the lean group (P = 0.16 and P = 0.06, respectively). Mean serum TAS levels were higher in obese group compared to the lean group (P = 0.001). mRNA expression of TERT and Nrf2 was increased in obese group compared to the lean group. mRNA expression of Nqo1 was similar in both the groups.

Conclusion:

Obese patients of T2DM are exposed to a greater degree of OS compared to the lean patients of T2DM.
A Systematic Review of Determinants Influencing Family Planning and Contraceptive Use
Authors: Feriani Pipit , Yunitasari Esti , Efendi Ferry , Krisnana Ilya , Ernawati Rini , Tianingrum Niken A. , Safaah Nurus
Published: September 2024

Background:

Reproductive health, crucial for public health and sustainable development, encompasses family planning and contraceptive use. However, global disparities persist in the adoption of family planning, highlighting the need for a comprehensive understanding of the complex factors shaping these reproductive health choices.

Materials and Methods:

Following Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines, we conducted a systematic search of the Scopus, ScienceDirect, PubMed, Web of Science, and ProQuest databases from July to August 2023. Inclusive criteria covered various study designs and populations, ranging from individuals to communities, and encompassed sociocultural factors. The review included open access articles published between 2018 and 2023, utilizing a combination of the keywords: Family planning determinants, Contraceptive use factors, Sociocultural factors in family planning, Individual-level influences on family planning, and Factors affecting contraceptive choices.

Results:

Data from 25 selected studies underscore the critical influence of determinants at both individual and community levels in shaping family planning behaviors. Key drivers at the individual level included education, age, knowledge, and attitudes. At the community level, factors such as geographical disparities and healthcare accessibility played pivotal roles. Sociocultural determinants, including media exposure, gender norms, and spousal dynamics, highlighted the need for culturally sensitive strategies.

Conclusions:

Advancing equitable family planning requires education, improved access, peer influence, and the active participation of husbands and male partners. Comprehensive programs should bridge the gap between knowledge and action, reduce disparities, and ensure equal access to contraception. Context-specific research and evaluating interventions are crucial steps toward achieving global reproductive health objectives.
Clinical Simulation in Nursing Students’ Safe Medication Administration: A Systematic Review
Authors: Shahzeydi Amir , Dianati Mansour , Kalhor Faramarz
Published: September 2024

Background:

Nursing students’ safe medication administration is a crucial aspect of ensuring patient safety. Clinical simulation is a novel teaching method applied to reduce factors threatening medication safety in the education of nursing students. Therefore, the aim of the present study was to conduct a review study in this field.

Materials and Methods:

The present review was conducted using keywords of education, clinical competence, medication safety, medication error, nursing student, clinical simulation, and educational strategies. Suitable articles published between 2000 and 2023 were systematically searched in various national and international online databases, including SID, Magiran, Ovid, Scopus, Web of Science, PubMed, ProQuest, and Google Scholar in both English and Persian languages.

Results:

A total of 855 articles were retrieved from the initial search findings. After eliminating duplicate and irrelevant articles based on predetermined criteria, a qualitative selection was conducted using CONSORT, MMAT, and JBI critical appraisal checklists. Ultimately, a selection of 11 articles was made, specifically focusing on medication safety education for nursing students through clinical simulation. The findings showed that using clinical simulation improved medication safety and safety knowledge among nursing students. Additionally, this approach was found to enhance their competence in medication administration.

Conclusions:

Based on the findings, clinical simulation is a safe and effective approach for enhancing nursing students’ proficiency in medication safety and administration. Therefore, it is recommended that nursing education authorities implement these findings to improve nursing students’ knowledge, performance, and competency in safely administering medications.
Detecting Age Prone to Growth Retardation in Children Through a Bi-Response Nonparametric Regression Model with a Penalized Spline Estimator
Authors: Islamiyati Anna , Kalondeng Anisa , Zakir Muhammad , Djibe Sultan , Sari Ummi
Published: September 2024

Background:

The growth of children aged 0–60 months can impact their subsequent growth and development. This study aims to identify the vulnerable age for boys and girls, who experience growth retardation within this age range.

Methods:

The study design used was a cross-sectional approach in which each child’s measurement data was only taken once. The data were obtained from weighing results at the Health Integrated Service Post in South Sulawesi Province in 2022. The number of data analyzed was 698 children, namely 369 boys and 329 girls by considering the factors of age, weight, and height. We used a nonparametric bi-response regression model estimated using a penalized spline. The knots used are 12, 24, 36, and 48 on each model.

Results:

The value of the penalized spline regression coefficient in the model indicates that the child’s growth is slowed down and is not within normal limits. This can be seen in the weight and height of boys from the age of reaching 12 months to 24 months, only increasing by about 0.3 kg and 0.3 cm. For girls, the problem occurs from the age of 24 to 36 months, namely their weight increases by about 0.6 kg, and their height increases by about 1 cm.

Conclusions:

The analysis results show that boys’ growth slows down at 2 years of age and continues until 5 years of age. In the case of girls, their growth begins to slow when they are 3 years old until they reach 5 years old.
Intensive Care Nurses’ Performance of Open versus Closed Endotracheal Suction on Critically Ill Patients in Ismailia City
Authors: Elmansy Fatma Mohamed , Elbqry Mohamed Goda , Aly Azza Anwar , Negm Ahmed Nader , Hafez Ahmed Ibrahem , Elgazzar Samia Eaid
Published: September 2024

Background:

Endotracheal Tube Suctioning (ETS), which involves either an open or closed suctioning system, is a crucial practice for mechanically ventilated patients. The nursing practice of airway suctioning is inevitable. This study was designed to compare the intensive care nurses’ performance of open versus closed endotracheal suction on critically ill patients in Ismailia City.

Materials and Methods:

A non-participant structured observational study design was conducted on a convenient sample (N = 63) at intensive care units at a teaching hospital through March and August 2022 to evaluate how nurses practice different procedures in open suctioning compared with the closed suctioning system of Endotracheal Suction (ES) through a 32-item structured checklist. Additionally, authors compared their levels of knowledge in both suctioning systems.

Results:

Approximately 75% and 65% of the study participants had a satisfactory level of knowledge about the open system compared with the closed system, respectively. The total percentage of patients who achieved a satisfactory level of practice was 72% for the open-system group, compared with 56% for the closed-system group. Overall, there were significant differences between total nurses’ performances in the open-system and closed-system systems. Independent sample t-tests revealed a statistically significant correlation between overall nurses’ performance in both systems (t = 6.04, p < 0.001).

Conclusions:

The findings revealed significant differences in nurses’ performance between open and closed-system suctioning. The researchers recommend in-service-led training programs to improve nurses’ performance, and other studies with larger sample sizes should be supported.
Sleep Quality and its Associated Factors among Nurses in a Tertiary Care Public Hospital in Puducherry District: A Cross-sectional Study
Authors: Kayaroganam Rajarajan , Sarkar Sonali , Satheesh Santhosh , Tamilmani Santhi , Sivanantham Parthibane , Kar Sitanshu Sekhar
Published: September 2024

Background:

Adequate sleep is essential for human beings to maintain optimal health. Medical professionals, including nurses, work in stressful environments that could affect their sleep quality. The objective of this study was to determine the prevalence and the factors associated with poor sleep quality among nurses in a tertiary care public hospital.

Materials and Methods:

This cross-sectional analytical study was conducted on 1217 nurses aged between 21 and 60 years from May 2019 to April 2020 in a tertiary care public hospital in Puducherry. Sleep quality was assessed using the Pittsburgh sleep quality index scoring system, and the workplace stress scale was used to assess workplace stress. The Chi-squared test and adjusted Prevalence Ratio (aPR) were used to determine the factors associated with poor sleep quality.

Results:

The response rate was 99% (1217/1229), and three-fourths of the participants were women (943, 77.50%). The mean (SD) PSQI score was 4.49 (2.98), and more than one-third of participants, 42.80% (95% CI: 40.10-45.70), had poor sleep quality. The prevalence of poor sleep quality was significantly higher among women (z = 2.33, p = 0.019) aPR (95% CI): 1.08 (1.01-1.16), those having severe to dangerous levels of workplace stress (z = 8.22, p > 0.001) aPR (95% CI): 1.54 (1.39-1.71) and chronic pain (z = 2.11, p = 0.016) aPR (95% CI): 1.09 (1.02-1.17).

Conclusions:

The prevalence of poor sleep quality among the study population was high. This highlights the urgent need for implementing health promotion programs among nurses.
An IoT-enabled device for remotely monitoring and controlling solar photovoltaic systems
Authors: Srinivasan P.  , Kannan K.
Published: September 2024

This article presents an Internet of Things (IOT) solution that focuses on managing and tracking the operation of a solar system and is intended for both home and commercial application. A MOSFET driver, a DC-DC SEPIC converter, a single-phase voltage source inverter with active clamping, and a DC-DC Landsman converter are all used by the system to condition electricity. This allows for real-time online contact with an internet server and includes measurements of the output voltage and current from the solar panel and battery to monitor DC load and AC load. The ESP32 Wi-Fi MOD and PIC microcontroller work together to seamlessly provide an online connection to the internet server. The outcomes of the experiments demonstrate how well voltage control works and how well IOT functions. Through a user-friendly GUI interface on the internet, users can effortlessly control the DC-DC converter and get real-time data on battery voltage, current, and state of charge by combining solar energy with the power source.
Maximizing Returns: A Deep Dive into the Financial Strategies of SMEs in Morogoro Municipality
Authors: Mhanganya Stephano , Kamuzora Aurelia , Utouh Harold
Published: September 2024

This study investigates the determinants of Return on Investment (ROI) among Small and Medium Enterprises (SMEs) in Morogoro Municipality using a cross-sectional research design and a multiple linear regression model. The analysis reveals that the capital structure, comprising private savings, bank credit, reserved earnings, non-bank loans, equity, and trade credit, plays a crucial role in influencing the financial performance of these businesses. The results indicate that private savings, non-bank loans, and trade credit are the most significant contributors to higher ROI, with coefficients of 0.305, 0.353, and 0.296, respectively, all significant at p<0.01. Bank credit also positively impacts ROI, though to a lesser extent, with a coefficient of 0.095 (p<0.05). However, reserved earnings and equity were not found to significantly affect ROI, suggesting that their effectiveness in enhancing profitability may depend on specific business strategies and resource allocation. The study suggests that SMEs should focus on leveraging private savings, non-bank loans, and trade credit to optimize their financial performance. Finally, it recommends that policymakers and financial institutions support SMEs in accessing diverse and flexible financing options to enhance their profitability and ensure sustainable business growth.
LEXICAL UNITS REPRESENTING THE NAMES OF OBJECTS FOR COOKING IN “DEVONU LUGOTIT TURK”
Authors: DADABOYEV Hamidulla
Published: September 2024

In Divanu lugat-it-turk vocabulary live colloquial speech of various Turkic tribes who lived in the Karakhanid state and family lexicon used in the first old Turkic literary language have significant place. In this article, the words of family lexicon related to household items names used in the process of cooking are discussed. In order to investigate these words’ formation and development stages we focused on the encyclopedic work created by the great genius of Mahmud Koshgari. The discovery of the technology of smelting iron ore by the Turkic peoples was considered an extraordinary event in the human society, and it had an important and positive significance in the radical change of the people's lifestyle and in the step forward. As a result, people had the opportunity to hunt wild animals, make and prepare weapons and armor, which are very necessary for fighting off raids, as well as tools and equipment for daily living. The names of the kitchen items used in cooking, recorded in Divanu lugat-it-turk, indicate that the national culture and household lifestyle of the ancestors was at a very high level. Keywords: Microgroup, Synonym, Live Colloquial Language, Syntagmatic Relationship, Cognate Turkic Languages.
The Evolution of the Conceptual Basis of Foreign Policy of the Republic of Azerbaijan
Authors: Samadova Hamida
Published: September 2024

Modern Azerbaijan is a nation that has been striving for independence since the early 20th century and achieved it in 1991 with the dissolution of the Soviet Union. Throughout this process, Azerbaijan underwent substantial cultural and political transformations, which contributed to the formation of a new national identity. Following its independence, Azerbaijan faced numerous economic and political challenges. The country aimed to transition from the Soviet economic model to a market economy, while concurrently grappling with internal and external political instability that threatened its stability. In recent years, however, Azerbaijan has made notable economic progress and has gained increased prominence on the global stage. The exploitation of energy resources has significantly bolstered the country's economic development. Additionally, Azerbaijan’s adept foreign policy has played a crucial role in enhancing its international reputation. In conclusion, modern Azerbaijan has experienced considerable advancement since gaining independence, achieving a higher standing in the international arena.
Teknik Mengajarkan Alat Musik Keyboard dalam Mengiringi Lagu Ibadah di Gereja Pada Kursusan Celvi Musik Tarutung
Authors: Nadeak Rowilson
Published: September 2024

Dalam tata ibadah di gereja, musik mempunyai peranan yang sangat penting dan memiliki tempat khusus dalam kedudukannya. Musik sangat berkaitan dengan berjalannya liturgis gereja, berkaitan erat dengan keahlian pemain musik dalam memainkan alat musik pengiring. Alat musik yang digunakan dalam pelayanan ibadah minggu, pada awalnya berawal dari alat musik orgel, kemudian berkembang menjadi piano. Gereja-gereja tua yang ada di Indonesia pada umumnya, dulunya menggunakan organ sebagai alat musik pengiring dalam tata ibadah minggu. Sejalan dengan berkembangnya zaman, keberadaan alat musik organ,lambat laun tersingkirkan dengan alat musik yang lebih modern lagi yaitu keyboard. Alat musik keyboard yang memiliki banyak sekali style / gaya musik yang mempengaruhi perubahan alat musik yang digunakan. Banyaknya antusias masyarakat yang ingin turut serta dalam kegiatan pelayanan dalam rumah ibadah, memicu semangat orangtua untuk memberikan pengetahuan bermain alat musik khususnya keyboard dalam memainkan lagu-lagu ibadah di gereja. Oleh karena itu, penulis mengangkat penelitian yang berjudul Tehnik mengajarkan alat musik keyboard dalam mengiringi lagu ibadah di Gereja pada kursusan Celvi Music Tarutung.
Efektivitas Token Economy untuk Meningkatkan Keaktifan Belajar Mahasiswa
Authors: Kusumawardani Ngarasati , Kurniasih An Nisa Tri , Jamaluddin Muhammad
Published: September 2024

Banyak mahasiswa yang hingga saat ini kurang aktif di kelas karena beban akademis dan non akademis. Padahal, pendidikan tinggi yang bermutu juga sangat penting untuk membentuk masyarakat yang kompeten dan profesional. Maka, perlu adanya solusi untuk meningkatkan keaktifan belajar mahasiswa melalui token economy. Penelitian ini bertujuan untuk melihat efektivitas sistem token economy sebagai intervensi untuk meningkatkan partisipasi aktif mahasiswa dalam pembelajaran. Penelitian ini menggunakan pendekatan kuantitatif dengan penelitian eksperimen menggunakan desain one group pretest-posttest. Teknik pengambilan sample dilakukan dengan metode purposive sampling berjumlah 8 orang mahasiswa psikologi angkatan 2021. Metode analisis data menggunakan uji reliabilitas dan uji hipotesis menggunakan paired sample t-test. Hasil penelitian menunjukkan bahwa token economy efektif dalam meningkatkan partisipasi aktif mahasiswa dengan perolehan nilai rata-rata keaktifan belajar mahasiswa sebelum diberi perlakuan adalah sebesar 53,43%, sedangkan sesudah diberi perlakuan rata-rata keaktifan belajar mahasiswa adalah sebesar 81,25% dengan selisih sebesar 27,82%.
Model Komunikasi Interpersonal Guru dan Siswa Pada Lembaga Pendidikan Non Formal Primagama KM10 Palembang
Authors: Rahmawati Novita , Hasmawati Fifi , Hamandia Muhammad Randicha
Published: September 2024

Artikel ini berjudul “Model Komunikasi Interpersonal Guru dan Siswa Pada Lembaga Non formal Primagama Km10 Palembang”. Yang menjadi rumusan masalah dalam penelitian adalah bagaimana model komunikasi interpersonal guru dan siswa pada lembaga non formal primagama km10 palembang. Tujuan penelitian ini adalah untuk mengetahui model komunikasi interpersonal guru dan siswa pada lembaga non formal primagama km10 palembang. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan teori analisis isi. Data yang dikumpulkan melalui dokumentasi dan wawancara. Dan teknik analisis data menggunakan teknik analisis isi. Hasil penelitian menjelaskan bahwa model komunikasi interpersonal guru dan siswa pada lembaga non formal primagama km10 palembang adalah menggunakan model interaktif dan teori yang digunakan dalam penelitian ini adalah teori (I-Thou) teori manusia yang mengakui sesamanya sebagai makhluk yang humanis, dan mereka saling membuka diri, bahkan kelebihan dan kekuranganya sekalipun.
A Bibliometric Analysis of Environmental, Social, Governance (ESG) and Firm Performance: A Pathway to Advancing SDG Movement
Authors: Kiflee Ag Kaifah Riyard , Hasbullah Nornajihah Nadia , Idris Nur Hafidzah , Harun Hazalinda , Bakar Mohd Hafiz , Anwar Saiful
Published: September 2024

Objective: Companies engage in ESG (Environmental, Social, and Governance) activities to enhance financial returns and demonstrate adherence to market practices. Despite the existence of ESG, corporate performance is often in conflict due to inconsistent results and arguments.
 
Theoretical Framework: Reflecting on that, this study uses a combination of bibliometric analysis and systematic literature review to examine the ESG literature and its impact on supporting the Sustainable Development Goals (SDGs). By utilising this approach, researchers can enhance their comprehension of ESG advancements by conducting quantitative bibliometric analysis and systematic review.
 
Method: Thus, this study presents a bibliometric analysis covering articles obtained from the Scopus Database published between 2016 and 2022. The co-occurrence analysis includes 233 keywords from 50 articles relevant to the study was evaluated using VOSviewer software.
 
Results and Discussion: The initial study concluded 121 articles related to ESG and corporate performance. This study opted for articles from the disciplines of business, management, and economics. As a result, 87 documents were selected. Co-authorship analysis showed that ESG analysis was associated with five main continents: Africa, the Americas, Europe and Oceania.
 
Research Implications: An overview of trends and development directions is also provided in this study to visually show the current interest of the researcher in the topic. The analysis focuses on finding the best authors, the best journals, active institutions and the best citations of sustainable development research.
 
Originality/Value: The bibliometric analysis effectively illustrates the evolution of ESG research and its potential to advance the SDGs, offering insights for future research in this field.
Optimizing Control of Fever & Pain in Clinical Settings – An in-Vitro Investigation of the Dissolution and Disintegration Characteristics of Optizorb Technology in Acetaminophen Tablets versus Other Marketed Products
Authors:   Haleon India (erstwhile GlaxoSmithKline Consumer Healthcare), Ali Asif , Narang Prashant ,   Haleon India (erstwhile GlaxoSmithKline Consumer Healthcare)
Published: September 2024

Reduced inter-patient variability and consistent therapeutic effects are prerequisites in formulating drugs for reliable fever and pain control. The bioavailability of paracetamol is variable, leading to variable onset and duration of action. Optizorb technology incorporates a patented technology aimed at rapid dissolution and absorption of active ingredients, and improving the bioavailability of paracetamol. This study compared the dissolution of various paracetamol formulations versus the patented 'Optizorb' technology-based paracetamol tablets (Crocin Advance 650), determined the rate of disintegration in aqueous media and resultant changes in pH, and analyzed the residue profile. The dissolution test utilized media closely resembling the gastrointestinal environment (0.1N HCl, pH 5.8 phosphate buffered medium and pH 6.8 phosphate buffered medium). The disintegration test was performed using 1,000 mL of water as disintegration media. In 0.1N HCL, Crocin 650 mg tablets released 61% of the drug at 1-minute time interval, and 94% at the 3-minute time interval. The disintegration time for Crocin 650 was 48 seconds in water. Crocin 650 exhibited complete disintegration and dissolution in water, leaving no residues in the medium. Crocin Advance 650 with Optizorb technology ensures rapid, consistent drug release and may provide clinically relevant reduction in inter- and intra-patient variability and improved bioavailability.
Actitudes, experiencias y perspectivas en investigación electiva en estudiantes de pregrado de Medicina de la Universidad de Oriente, núcleo Anzoátegui
Authors:   Universidad de Oriente, Núcleo Anzoátegui. EMA Research Group, Rivero-Moreno Yeisson
Published: September 2024

Introducción: La investigación científica juega un papel fundamental en la práctica médica actual y en el desarrollo académico a nivel mundial. La productividad científica varía considerablemente entre países según su grado de desarrollo. Objetivo: Analizar las actitudes, experiencias y perspectivas en investigación entre los estudiantes de medicina en una universidad autónoma de Venezuela. Materiales y métodos: Se realizó un estudio transversal mediante una encuesta electrónica entre diciembre de 2023 y febrero de 2024, dirigida a estudiantes de medicina de la Universidad de Oriente (UDO), núcleo Anzoátegui.
Factores de Hospitalización por Varicela en Montería-Colombia 2016-2023
Authors:   Bacteriólogo, Especialista en Microbiología Clínica, Msc Epidemiología. Docente Universidad Libre Seccional Barranquilla, Lorduy Gómez Jaime
Published: September 2024

Introducción: La varicela es una enfermedad contagiosa que afecta tanto a niños como a adultos, puede generar complicaciones que llevan a la hospitalización. En Colombia la hospitalización por varicela es baja y va relacionada con complicaciones como sobreinfección bacteriana, alteraciones neurológicas, hematológicas y respiratorias. Objetivo: Determinar los factores que inciden en la hospitalización en pacientes con varicela de la ciudad de Montería, Colombia durante el período 2016-2023. Materiales y Métodos: Estudio descriptivo transversal retrospectivo con una muestra poblacional de 6 949 pacientes entre marzo de 2016 y marzo de 2023.
Crop Care Tech: A Web Based Application for Crop, Fertilizer Recommendation, Disease Detection by Using ML, DL
Authors: B. Shireesha  , M. Vinitha  , K. Vamsi  , Shaik Shabber Ali  , Umadevi Sri Anuhya Nunna
Published: September 2024

Agriculture is the Backbone of the India’s economy. Agriculture is the foundation of human civilization, embodying the art and science of cultivating crops and rearing livestock for sustenance and economic prosperity. Due to the poor weather, climate conditions, lack of proper care there are huge losses to the farmers in terms of their productivity. Because of not much knowledge, education in the rural area farmers tend to commit mistakes by not giving their crop proper treatment like good fertilizers to grow the crop, taking care of the disease which has been caught up by the crop. This study aims to develop a website utilizing machine learning models for crop recommendations, taking into account inputs such as pH values, temperature, and soil nutrients like nitrogen, potassium, phosphorus etc. Various machine learning algorithms including logistic regression, linear regression, support vector machines, random forests, naive bayes, xgboost, decision trees are used, with random forests and xgboost gives the higher prediction results.  So basically, we are expecting that after taking valuable inputs from user like soil nutrients, images of the crop we will predict the desired output with highest efficiency. The main objective of this project is building a website which will help farmers to make the effective cultivation by providing good information like which crop is suitable for their soil, and which fertilizers are suitable to grow. Ultimately, these systems serve as a crucial tool in advancing modern agriculture, leveraging technology and data analysis to assist farmers in making decisions that contribute to food security and agricultural sustainability. Accessible through user-friendly platforms, crop recommendation systems empower farmers to harness the benefits of technology and data, thereby enhancing agricultural productivity, financial gains, and global food security through these modern agricultural advancements.
DEVELOPMENT OF A BEAM DELIVERY SYSTEM FOR THE PROTON RADIATION THERAPY ONCO-OPHTHALMOLOGICAL COMPLEX PROJECT «OKO»
Authors:   National Research Center ", Chernykh A.N. ,   Kurchatov Institute", Klenov G.I. ,   National Research Center "Kurchatov Institute", Krasilshchikov K.S. ,   National Research Center "Kurchatov Institute", Granin D.I. ,   National Research Center "Kurchatov Institute" - PNPI, Lebedeva Z.S. ,   National Research Center "Kurchatov Institute" - PNPI, Belkin V.V. ,   JSC NPO MRTZ, Grishin S.V. ,   JSC NPO MRTZ
Published: September 2024

The article provides a brief overview of the development of proton beam therapy (PBT) in the world and, in particular, specialized facilities for proton onco-ophthalmology in Russia. The current results of the work on the implementation of the project to create a complex of proton radiation therapy for onco-ophthalmic patients based on the Ts-80 cyclotron of the National Research Center "Kurchatov Institute" - PNPI, carried out within the framework of the Fed-eral scientific and technical program approved by the Government of the Russian Federation in March 2020, are presented. The paper presents the requirements for the characteristics of the proton beam and the features of the formation of dose distributions for PBT of patients with localizations in the eye area, and the current results of the development of a beam deliv-ery system of the proton beam and the results of modeling in MC TOPAS
THE EFFECT OF NO AND NITRITES ON THE LEVEL OF ATP IN LYMPHO-CYTES AND THE RELATIONSHIP WITH THE LEVEL OF AUTOANTIBODIES TO GLUTAMATE RECEPTORS IN CHILDREN WHO HAVE SUFFERED A TRAU-MATIC BRAIN INJURY
Authors:   National Medical Research Center for Children's Health", Sorokina E.G. ,   of the Minis-try of Health of Russia, Reutov V.P. ,   Institute of Higher Nervous Activity and Neurophysiology of the  Russian Academy of Sciences, Semenova Z.B. ,   Research Institute of Emergency  Pediatric Surgery and Traumatology, Karaseva O.V. ,   Research Institute of Emergency  Pediatric Surgery and Traumatology, Pinelis V.G. ,   National Medical Research Center for Children's Health" of the Minis-try of Health of Russia, Smirnov I.E. ,   "National Medical Research Center for Children's Health" of the Minis-try of Health of Russia
Published: September 2024

The article presents experimental data on the effect of NO-generating substances (nitrites and S-Nitrosocysteine) on the content of ATP in human lymphocytes. In children who suffered traumatic brain injury (TBI), the level of ATP in lymphocytes and the content of autoantibod-ies (aAb) to glutamate receptors (NMDA GluRc) and neuroglial protein S100b were deter-mined in the dynamics of the post-traumatic period.
NITRIC OXIDE AND ASCORBIC ACID IN THE MACROPHAGES
Authors:   Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Kuropteva Z.V.
Published: September 2024

The effect of ascorbic acid (AA) on the formation of nitric oxide in mouse peritoneal mac-rophages was studied. ESR and UV spectroscopy revealed a significant increase in nitric oxide formation in a suspension of macrophages with AA incubated at room temperature.
CHANGES IN MILK OF TPH2 HET MICE UNDER EXPOSURE TO STRESS
Authors:   V.M. Gorbatov Federal Research Center for Food Systems,  Russian Academy of Sciences, Kibitkina A.A. , Vasilevskaya E. R. ,   V.M. Gorbatov Federal Research Center for Food Systems,  Russian Academy of Sciences, Ilin N.A. ,   V.M. Gorbatov Federal Research Center for Food Systems,  Russian Academy of Sciences, Tolmacheva G.S. ,   V.M. Gorbatov Federal Research Center for Food Systems,  Russian Academy of Sciences
Published: September 2024

The relationship between neuroregulatory factors of the brain and the composition of breast milk is an interesting and little-studied topic. The article is aimed at studying changes in the chemical composition of the milk of mice prone to the development of affective disorders (heterozygous for TPH2) under the influence of stress and without stress relative to the milk of ordinary mice. Raman spectroscopy (wavelength 785 nm, focal length 50x) was used for the study. Het mouse milk has a less rich protein and peptide profile, but the range of fatty acids, especially under stress, increases.
Neonazism in youth environment: emergence trends
Authors: Кочесоков Р.Х.
Published: September 2024

В статье анализируются тенденции неонацизма в молодежной среде. Отмечается широта использования термина «неонацизм». Ему присущи шовинизм, расизм, ксенофобия, антисемитизм, гомофобия, различные черты фашизма. Многие праворадикальные группировки используют нацистскую или схожую с ней символику. Во многих европейских странах проблема возрождения нацизма становится актуальной, это происходит из-за неграмотной миграционной политики, упадка экономики, а также в целом сложной политической и социальной обстановки. Нацистский вопрос не проходит сам собой. Кроме жесткой коррекции общественного поведения, необходимо устранять и те факторы, которые вызывают озлобленность населения на представителей других национальностей и культур. Россия активно работает в данном направлении, поэтому отрицательно оценивает действия тех стран, которые не только не препятствуют возрождению радикально правых идей, но и помогают их продвижению.

The article analyzes the trends of neo-Nazism among young people. The breadth of the use of the term “neo-Nazism” is noted. It is characterized by chauvinism, racism, xenophobia, anti-Semitism, homophobia, and various features of fascism. Many right-wing radical groups use Nazi or similar symbols. In many European countries, the problem of the revival of Nazism is becoming urgent, this is due to illiterate migration policies, the decline of the economy, as well as the generally difficult political and social situation. The Nazi question does not go away by itself. In addition to strict correction of social behavior, it is necessary to eliminate those factors that cause anger among the population against representatives of other nationalities and cultures. Russia is actively working in this direction, therefore, negatively evaluates the actions of those countries that not only do not prevent the revival of radical right-wing ideas, but also help to promote them.
The Nexus of Water Scarcity and Climate Change: Understanding Interconnected Challenges and Formulating Resilient Strategies
Authors: Khan Tanzim , Samiullah Mohammed , Rouf Istiak , Sultana Sanjida , Rahman Shiblur , Rahman Bazlur , Khanum Roufa
Published: September 2024

Purpose: This research explores the intricate relationship between water scarcity and climate change, recognizing their interconnected challenges and the need for resilient strategies. Through a multifaceted approach, the study examines global impacts, socio-economic ramifications, and strategies for mitigation.
Methodology: Using qualitative research methods, diverse perspectives from 40 individuals across various sectors are captured through interviews. Thematic analysis of these insights reveals the nuanced dynamics of the nexus between water scarcity and climate change.
Findings: The results underscore the urgent need for comprehensive understanding and action. Rising temperatures, altered precipitation patterns, and melting glaciers exacerbate water stress, threatening ecosystems, societies, and economies globally. Socioeconomic implications include reduced agricultural productivity, compromised food security, and increased vulnerability of marginalized communities. Resilient strategies are proposed, including Integrated Water Resource Management, Climate Resilient Infrastructure, and Sustainable Agricultural Practices. Additionally, fostering Community Engagement, Policy Reform, and International Cooperation are vital. Nature-based solutions offer promise in mitigating impacts, while education and awareness-raising efforts are crucial for building resilience.
Unique Contribution to Theory, Practice and Policy: This research provides a roadmap for addressing the interconnected challenges of water scarcity and climate change, emphasizing the importance of coordinated action and sustained commitment at all levels. By implementing these strategies, we can pave the way for sustainable water management and adaptation to a changing climate, ensuring the well-being of present and future generations.
Faith-Based Service Needs: An Implication to Developing Halal Friendly Tourism in Thailand.
Authors: Islam Rasmee , Suwaree Ashton Ann
Published: September 2024

Halal tourism is a fast-growing trend that has attracted attention from both Muslim and non-Muslim travellers. As an inclusive tourism product, Halal tourism is viewed as niche tourism that prioritises Halal activities. To provide a better understanding of Muslim friendly tourism, this study explores in-depth what constitutes services using the Faith-Based Service Needs model. A qualitative approach was employed to interview 40 Thai Muslim travellers who have experience travelling to non-Muslim destinations. NVivo 14 was used to analyse data. Findings revealed the needs of Thai Muslim travellers are slightly different from the needs captured in the Global Muslim Travel Index. Particularly, need to have service needs comprising of Halal food, prayer facilities, and no Islamophobia; good to have service needs comprising water-friendly washrooms, Ramadhan services, and local Muslim experiences; and nice to have service needs consisting of recreational facilities and services, no non-Halal activities, and social causes. Findings provide implications for Muslim friendly service including the fundamental aspects to be focused on as well as additional values which will increase competitive advantages for non-Muslim destinations.
ANALYSIS OF PLANT MOBILOM BY AMPLIFICATION OF DNA ENRICHED IN EXTRACHROMOSOMAL RING MOLECULES
Authors: Меркулов П.Ю. , Киров И.В.
Published: September 2024

Мобильные генетические элементы (МГЭ) занимают значительную часть геномов растений и животных и вносят большой вклад в их эволюцию и адаптацию. Способность МГЭ к транспозиции – перемещению и/или амплификации в геноме позволяет им формировать так называемый мобилом. По типу транспозиции МГЭ делятся на два больших класса: ДНК-транспозоны, перемещающиеся по геному по принципу «вырезатьвставить», и ретротранспозоны, использующие РНК посредник для транспозиции (принцип «копировать-вставить»). Среди МГЭ растительных геномов наиболее широко представлены элементы с длинными концевыми повторами - LTR-ретротранспозоны.

Mobile genetic elements (MGEs) occupy a significant part of the genomes of plants and animals and make a great contribution to their evolution and adaptation. The ability of MGEs to transposition - move and / or amplify in the genome allows them to form the so-called mobile. According to the type of transposition, MGEs are divided into two large classes: DNA transposons, which move along the genome according to the “cut-paste” principle, and retrotransposons, which use an RNA intermediary for transposition (the “copy-paste” principle). Among the MGEs of plant genomes, elements with long terminal repeats, LTR retrotransposons, are most widely represented.
EVALUATION OF THE EFFICIENCY OF THE USE OF PHOSPHORITE MEAL BY PLANTS OF DURUM WHEAT AND RYE USING THE SYSTEM OF DIGITAL PHENOTYPING
Authors: Баженов М.С.
Published: September 2024

Достаточное фосфорное питание важно для получения высоких урожаев сельскохозяйственных культур. Фосфоритная мука является самым дешевым фосфорным удобрением, производство и применение которого создает наименьшую угрозу для окружающей среды [1]. Однако известно, что растения пшеницы обладают плохой способностью усваивать фосфор из труднодоступных форм, а гены короткостебельности, вероятно, еще больше снижают эту способность [2].

Sufficient phosphorus nutrition is important for obtaining high crop yields. Phosphorite flour is the cheapest phosphate fertilizer, the production and use of which poses the least threat to the environment [1]. However, it is known that wheat plants have a poor ability to assimilate phosphorus from hard-to-reach forms, and short stem genes probably further reduce this ability [2].
STUDY OF CXCR1 GENE POLYMORPHISM AND ITS EFFECT ON MILK PRODUCTIVITY OF COWS
Authors: Зимина А.А. , Романенкова О.С. , Сермягин А.А.
Published: September 2024

Современные методы молекулярной генетики позволяют определять наследуемые по кодоминантному типу аллельные варианты генов, связанные с молочной продуктивностью. К настоящему времени выявлено большое количество генов, ассоциированных с параметрами молочной продуктивности, определена их локализация в хромосомах и последовательность пар нуклеотидов в их молекулярной структуре, установлены причины возникновения полиморфизма генов в результате точковых мутаций в соответствующих локусах молекул ДНК.

Modern methods of molecular genetics make it possible to determine codominantly inherited allelic variants of genes associated with milk production. To date, a large number of genes associated with milk productivity parameters have been identified, their localization in chromosomes and the sequence of nucleotide pairs in their molecular structure have been determined, and the causes of gene polymorphism as a result of point mutations in the corresponding loci of DNA molecules have been established.
CHARACTERISTICS OF HIGH CATTLE OF DAGESTAN BY STR-MARKERS
Authors: Волкова В.В. , Денискова Т.Е. , Абдельманова А.С. , Романенкова О.С. , Хожоков А.А. , Сермягин А.А. , Зиновьева Н.А.
Published: September 2024

Большие территории горных пастбищ Республики Дагестан, дешевый пастбищный корм и большая продолжительность пастбищного сезона благоприятствуют разведению и выращиванию крупного рогатого скота.

Large areas of mountain pastures in the Republic of Dagestan, cheap pasture fodder and a long pasture season favor the breeding and rearing of cattle.
CREATION OF A SYSTEM FOR GENETIC ANALYSIS OF SUGAR BEET LINES AND HYBRIDS (BETA VULGARIS) ON THE BASIS OF MICROSATELLITE ANALYSIS
Authors: Шалаева Т.В. , Шилов И.А.
Published: September 2024

Сахарная свёкла (Beta vulgaris L.) является важной технической культурой, корнеплоды которой используют, в основном, для получения сахара. В 2020 году доля семян сахарной свёклы отечественной селекции составляла 3,05% от всей площади посева, поэтому создание высокопродуктивных гибридов является приоритетным направлением в селекции сахарной свёклы. Коммерческие гибриды сахарной свёклы получают в результате сложного, минимум трёхкомпонентного, скрещивания выровненных МС-линии, линии(й) О-типа и линии(й)-опылителя. Такие линии отбирают путем продолжительного повторяющегося самоопыления по морфологическим и хозяйственно-ценным признакам (урожайность, содержание сахара и др.). При этом возможность использования фенотипических признаков при отборе ограничена их зависимостью от условий выращивания и стадии развития растений [1].

Sugar beet (Beta vulgaris L.) is an important industrial crop whose roots are mainly used for sugar production. In 2020, the share of sugar beet seeds of domestic selection was 3.05% of the total planted area, so the creation of highly productive hybrids is a priority in sugar beet breeding. Commercial sugar beet hybrids are produced by a complex, at least three-component, crossing of aligned MC-line, O-type line(s) and pollinator line(s). Such lines are selected by long-term repeated self-pollination according to morphological and economically valuable traits (yield, sugar content, etc.). At the same time, the possibility of using phenotypic traits in selection is limited by their dependence on growing conditions and the stage of plant development [1].