bluuebunny/crossref_metadata_2025 huggingface dataset:
Monitoring of Muscle Relaxation in Routine Anesthesia Practice: Three-year Experience
Authors: Chuprin Sergey Vyacheslavovich , Sushkova O. V. , Girinskaia L. N. , Kuznetsov S. A. , Myasnikova V. V.
Published: August 2021

Neuromuscular block is a really significant component of anesthesia during surgery operations. At this time, individual sensitivity to neuromuscular blocking differs considerably and depends on great number of factors. The main task of conduct of neuromuscular monitoring is exclusion of residual block and recovery of neuromuscular conductivity. We present analysis of three years’ experience of application of monitoring of neuromuscular conductivity. The aim of the research is the estimation of effectiveness of usage of monitoring of neuromuscular conductivity in daily practice of anesthesia service for provision of patients’ security and formation of comfortable conditions for surgeons’ work. Materials and methods. In our research, we included 4459 patients who had operating treatment under general anesthesia. All the patients were divided in two groups. In the first group (2355 patients) during anesthesia there used monitor TOF-Watch SX (Organon, Ireland). In the second group (2104 patients) monitoring of neuromuscular conductivity was not performed. Results. The received results lead to the conclusion that application of monitoring of neuromuscular conductivity allowed to decrease statistically number of incidents connected with insufficient neuromuscular blocking or impaired reversion of neuromuscular block. Absence of statistically considerable differences in quantity of hyperdynamic reactions in the circulatory system connected with intubation, probably, is caused by great quantity of heterogeneous factors of influence on this index. Also, application of monitor of neuromuscular conductivity made it possible to conform to a surgeon’s expectations, ensuring muscular relaxation suitable for surgery conditions. Conclusion. Usage of monitors of neuromuscular conductivity in routine anesthesia practice is necessary and essential for ensuring patients’ security and creation of comfortable conditions for surgeons work.
Selective Sorption of Endotoxin in Combined Therapy of Post-Traumatic Abdominal Sepsis
Authors: Zaitsev R. R. , Yakovlev Aleksey Yurevich , Abramov A. V. , Ryabikov D. V. , Chistyakov S. I. , Il’in Y. V.
Published: August 2021

The investigations of the dynamics of lipopolysaccharide and presepsin in patients with closed abdominal trauma in the early post-traumatic period and after the development of abdominal sepsis. It revealed a biphasic rise of sepsis markers on stage fill hypovolemia and sepsis during subsequent development. High-performance determined early consistent application of selective sorption of lipopolysaccharide using «LPS adsorber» (Alteco, Sweden) and prolonged veno-venous hemofiltration in relation to the relief of endotoxemia and prevent the progression of multiple organ failure at post-traumatic abdominal sepsis.
Syndrome of Postnarcosis Excitation and its Prophylaxis in Anesthesia with Sevoflurane in Pediatric Oncology
Authors: Tumanyan Sergey V. , Semiletkina E. Yu. , Rozenko D. A.
Published: August 2021

Introduction. Sevoflurane is the «gold standard» in pediatric anesthesia, because Does not irritate the upper respiratory tract, has a cardioprotec- tive effect, is easily controlled. Along with this, sevoflurane also has side effects, of which the most interesting is the syndrome of post- narcotic excitement, expressed by expressed anxiety, motor excitement, negativism. For its prevention, dexmedetomidine can be used. Objectives: is to select the optimal method of prevention of post-nasal exacerbation syndrome (SPNV) in young children with oncological pathology with sevoflurane inhalation anesthesia. Materials and methods. 90 children with oncological pathology aged from 1 year to 4 years, body weight from 9 to 18 kg, physical status according to ASA II–III were examined. Depending on the method of prevention of SPNV, children were divided into three groups: 1st group of children who had undergone sevoflurane inhalation anesthesia; 2nd group of children who received propofol, after anesthesia with sevoflurane; 3rd group — children with intranasally injected dexmedetomidine, prior to anesthesia with sevoflurane. Results. Administration of propofol at the end of inhalation with sevoflurane prevents the development of SPNV in children in 82.8% of cases, prolongs the phase of medicamentous sedation, reduces hypersympathicoto- nia. Short-term depression of respiration in response to the administration of propofol requires 100 % oxygen inhalation. Conclusion. Intranasal administration of dexmedetomidine 30 minutes prior to the onset of anesthesia prevents the development of SPNV in children after inhalation anesthesia with sevoflurane in 90% of cases.
Preoperative Assessment of a Patient’s Functional Status. Current State of the Problem
Authors: Tsygankov Kirill A. , Shсhegolev A. V. , Lahin R. E.
Published: August 2021

The article is devoted to the significant and actively discussed problem of the prognosis of the complications development in non-cardiac surgery. Despite the progress and the increasing use of intraoperative monitoring, the improvement of the anesthesia methods and the success of clinical pharmacology, the importance of surgical and drug aggression in the manifestation of mechanisms of surgical stress remains. In these conditions, the role of anesthesiologists in providing patient safety during surgical intervention and anesthesia becomes even more important, as well as in the early postoperative period. It should be noted that, despite a large number of publications concerning patients’ functional status assessment and the prognosis of complications, the data about informative methods of preoperative prediction of complications during surgery and anesthesia is almost absent. At the same time, at the current level of science and anesthesiology and resuscitation practice development, the methods for determining the risk and predicting complications should be maximally objectified. All of the circumstances above determine the urgency of searching for opportunities to improve anesthesia safety with the help of objective prediction of the complications development.
The Influence of Polymorphism of the Μ-opioid Receptor OPRM1 A118G on the Doses of Narcotic Analgesics in the Early Postoperative Period (Meta-Analysis)
Authors: Makharin Oleg A. , Genilo V. M.
Published: August 2021

Objectives of the study was the compilation and analysis of available data on the influence of polymorphism of the μ-opioid receptor OPRM1 A118G on the doses of narcotic analgesics in the early postoperative period. Material and methods. The information was taken from SCOPUS, MedLine, EMBASE. We analyzed 34 studies. The inclusion criteria in meta-analysis: the original study on this issue. Exclusion criteria: reviews, articles concerning the influence of polymorphism on pain not related to surgical treatment (childbirth, cancer pain, chronic pain), as well as papers in which the authors studied the influence of polymorphism of the μ-opioid receptor OPRM1 A118G on the doses of narcotic analgesics infused in the epidural or intrathecal space. 6 works (1691 patients) were included in the meta-analysis. We analyzed the difference in the need for narcotic analgesics in the first 24 hour. Results. We found that homozygous carriers of A-allele of the μ-opioid receptor OPRM1 needed lower doses of narcotic analgesics compared with heterozygous (fixed effects model; Z = −10,172; p = 0.0001; I2 = 54.1 per cent), and homozygous carriers of G-allele(fixed effects model; Z = −6,543; p = 0.0001; I2= 81,7 %). Conclusion. Polymorphism of the μ-opioid receptor OPRM1 A118G affects the individual need for narcotic analgesics in the early postoperative period.
Predictors of the Generalization of Infectious Process
Authors: Vitik A. A. , Shen Natalia P. , Sukhanova N. V. , Pylenko L. N.
Published: August 2021

Objectives. This article provides results of the retrospective analysis of the medical records of the patients treated at the septic ICU. Results. The basic predictors of the generalization of infectious process, their authenticity and statistical significance are revealed using bilateral paired rank correlation analysis. Conclusion. Pointing out such factors as elderly and senile age, diabetes mellitus and traumatic operations among factors which do not affect the generalization of the infectious process was totally new in the study.
Perioperative Management of Patients with Chronic Renal Failure
Authors: Sinkov Sergey V. , Grigor’ev S. V.
Published: August 2021

The review presents modern approaches to managing patients with chronic kidney disease at various stages of the perioperative period. Among patients requiring surgical intervention, the proportion of patients with initially impaired renal function is increasing, many of them are on programmed dialysis. Reduction of kidney function is observed in 36 % of persons over the age of 60 and in 16 % of patients of working age. The main goal of perioperative management of the patient with concomitant renal pathology is the prevention of the development of acute renal damage on a background of chronic. Such patients require more careful monitoring at all stages of treatment, a special infusion therapy approach, continuity during renal replacement therapy, correction of analgesics, anesthetics, antimicrobials and anticoagulants doses. Non-compliance with these principles is inevitably associated with an increase in the frequency of perioperative complications and mortality.
Fluid Management History
Authors: Pshenisnov Konstantin V. , Alexandrovich Yu. S. , Alexandrovich V. Yu.
Published: August 2021

The article is devoted to the history of development of fluid management as a treatment method, special attention is paid to pioneers and founders of the modern concepts of fluid management, the evolution of various crystalloid and colloid solutions for fluid therapy is presented.
A Clinical Case of Headaches after Spinal Anesthesia Conservative Treatment
Authors: Lakhin Roman E. , Kadacki D. A. , Goncharov V. G.
Published: August 2021

Introduction. We present a clinical case of conservative treatment for post-dural puncture headache. Conservative treatment is effective with caffeine, gabapentin, theophylline and hydrocortisone, other medicines need clarification (sumatriptan, adrenocorticotropic hormone, pregabalin). For sumatriptan a history of migraine headaches can be an indication. In this clinical case post-dural puncture headaches developed after spinal anesthesia for phlebectomy. The bed rest and caffeine administration have not succeeded. On the third day, after revealing history of migraine headaches, sumatriptan was prescribed: 50 mg orally along with the previous conservative therapy. In three hours the headache regressed. The second 50 mg of sumatriptan were given the following day. The headaches never came back. The patient was discharged on the 8th day. A phone call in a week after discharge showed the headaches did not come back. Conclusion. Thus, prescription of sumatriptan to the patient with a migraine headaches history showed high efficiency, allowing pain treatment, quick activity increase, significant health improvement.
CLINICAL PROFILE AND OUTCOME OF COVID-19 PATIENTS WITH REQUIREMENT OF OXYGEN THERAPY FOR GREATER THAN ONE WEEK
Authors:   M.D General Medicine, Assistant Professor, Sri Atal Bihari Vajpayee Medical College & Research Institute, Karnataka India., B.B Supriyaa , Kumar A.S Manoj ,   M.D General Medicine Dr B R Ambedkar Medical College & Hospital., Bhakthavatchalam N. ,   Head Of Department General Medicine Dr B R Ambedkar Medical College & Hospital.
Published: August 2021

The novel coronavirus disease (COVID-19) pandemic, caused by the highly contagious severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), is still at its height causing thousands of deaths each week.Although several large randomized drug trials are underway, current survival from severe COVID-19 de- pends entirely on providing the best possible supportive care.1 Data from China suggests that although the majority of people with COVID-19 have mild illness (40%) or moderate illness (40%) about 15 % of them have se- vere illness requiring oxygen therapy, and 5% will be critically ill requiring inten- sive care unit treatment.2,3 Oxygen therapy is recommended for all moderate, severe and critical COVID-19 patients, with low doses ranging from 1-2 L/min in children and starting at 5 L/min in adults with nasal cannula, moderate flow rates for use with venturi mask (6-10 L/min) or higher flow rates (10-15 L/min) using a mask with reservoir bag. In addition, oxygen can be delivered at higher flow rates and in higher concentrations, using high-flow nasal cannula (HFNC) devices, non-invasive ventilation (NIV) and invasive ventilation devices.4 In this study we would like to identify the risk factors leading to prolonged oxygen requirement in COVID-19 patients.This information will help us in managing our resources effectively in a resource-limited setting by preparing the mindset of the patients early on in the admission for home oxygenation. The aim of the study is to assess the clinical profile and outcome of COVID-19 patients requiring oxygen therapy for more than one week duration.
CORRELATION BETWEEN FATTY BINDING PROTEIN 1 (FABP1) AND DIABETES TYPE 2 (T2DM)
Authors:   Misr University for Science and Technology, Egypt., Ashraf Abd Elhady Sofia , Mohamed Mansour Asmaa ,   Division of Biochemistry, Chemistry Department, Faculty of Science, Fayoum, Egypt., Shalby Hassan ,   Internal Medicine Department, Faculty of Medicine, Misr University for Science and Technology, Egypt., Fawazy Naglaa ,   Clinical and Chemical Pathology Department, National Institute of Diabetes and Endocrinology, Egypt., Sakr Yasser ,   Clinical and Chemical Pathology Department, National Institute of Diabetes and Endocrinology, Egypt., A. Barakat Abeer ,   Biochemistry Department, National Hepatology & Tropical Medicine Research Institute. Clinical and Chemical Pathology Department, El Sahel Teaching Hospital., H. Eldeeb Hala ,   Clinical and Chemical Pathology Department, El Sahel Teaching Hospital., Sobhy Adaroas Ahmed ,   Clinical and Chemical Pathology Department, El Sahel Teaching Hospital., Salah Wafaa ,   Internal Medicine, National Institute of Diabetes and Endocrinology, Egypt., S. Soliman Amina ,   Nutrition and Food Science, National Institute of Diabetes and Endocrinology., Ramdan Ezz AL Arab Mohamed ,   Hepatology Department, Ahmed Maher Teaching Hospital, Cairo, Egypt.
Published: August 2021

Background: Diabetes mellitus is best described as a condition that is characterized by postprandial hyperglycemia that has two types; diabetes type 1 and type 2. Many patients with type 2 diabetes can be asymptomatic. There are many novel biomarkers for the detection of diabetes type 2, such as FABP1, which is investigated as a marker to detect patients with diabetes type 2. Aim: The aim of the study was to investigate FABP1 in Patients with diabetes type 2 and to find the correlations between FABP1 and fasting insulin in those patients. Methods: Samples were collected from 99 diabetic patients and 85 samples of healthy participants as the control group. All participants were subjected to liver enzymes (ALT and AST) lipid profile (triglycerides, HDL, LDL, and cholesterol), T-billirbun, Albumin, Alp, AFP, BMI, S-creatinine, Hb, Fatty acids, F. Insulin, CA19.9, HbA1c, and Fbs that were done by an autoanalyzer. The serum level of fatty acid-binding protein 1 was measured by SunRed human FABP1 Elisa kits. Results: Data was represented as mean Â± standard deviation or median with statistically significant values of ALT, AST, ALP, PT, and INR (at P< 0.05). Findings revealed a significant positive correlation between our marker FABP1 and TG, cholesterol, LDL, Fasting insulin, and CA19.9, Conclusion: FABP1 can be used as a novel marker to detect patients with diabetes type 2.
INFRASTRUCTURES ANS FACILITIES MANAGEMENT IN THE MADRASAH ALIYAH PESAWARAN, LAMPUNG PROVINCE, INDONESIA
Authors:   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., a Wahyan , Etek Yurnalis ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., Rosidin Undang ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., Dermawan Oki ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia., b Koderi ,   Post-Graduate Program of Islamic Education Management Study Program, Raden Intan State Islamic University of Lampung, Indonesia.
Published: August 2021

Educational infrastructure is an essential factor in improving learning efficiency and the quality of education. This study aimed to analyze and describe the management of infrastructures which includes planning, implementation, and evaluation in Madrasah Aliyah, Pesawaran Regency, Lampung, Indonesia. This study is field research using a qualitative approach. The research data were collected through observation, interviews, and documentation. The research locations were Madrasah Aliyah Negeri 1 Pesawaran and Madrasah Aliyah Mathlaul Anwar Pesawaran. The results showed that the planning of educational facilities and infrastructures in Madrasah Aliyah Negeri 1 Pesawaran and Madrasah Aliyah Mathlaul Anwar Pesawaran have been carried out in several stages, namely school coordination meetings, determining school programs, and determining the needs for educational facilities and infrastructures. The facilities and infrastructures at Madrasah Aliyah Negeri 1 have been obtained through purchasing, manufacturing, grants or assistance, loans, recycling, exchanging, and repairing or reconditioning. There are two funding methods for infrastructures, namely the APBN DIPA and from the committee. On the other hand, Madrasah Aliyah Mathlaul Anwar is an autonomous Madrasa that has its own budget, namely the funding that comes from the Madrasah itself and the funding from the government, BOS funds, and donors. The facilities and infrastructures have been obtained based on the principals decision by coordinating with the treasurer. The facilities and infrastructures have been procured through the collaboration between several suppliers and large shops. The facilities and infrastructures inventory data at Madrasah Aliyah Negeri 1 Pesawaran and Madrasah Aliyah Mathlaul Anwar Pesawaran have been registered using symbols or codes as the substitutes for the name or description for each item groups.
THE DEVELOPMENT OF GUIDELINES ON QUALIFICATION OF UMRAH MUTAWWIF IN MALAYSIA
Authors: Anuar Khalid Khairul , Abdul Rahim Nik Abdul Ghani Nik
Published: August 2021

Career as umrah mutawif has gained an admirable place in society, recently. Nevertheless, from the legal and administrative perspective, there is no specific entity that regulates, monitors, and coordinates the management of umrah mutawif in Malaysia. Therefore, this article will analyze the need to establish proper qualifications guideline that canbe used to qualify a person before venturing into the profession of umrah mutawif. This is a qualitative study, adopting data collection process through library research methods, semi-structured interviews, and the involvement of researcher himselfas umrah mutawif. The study has established that there is critical need to develop qualifications guideline for umrah mutawif that could serve as a reference and assessment tools for the travel agents as umrah package operators, in selecting their umrah mutawif that operates under their company and will principally be guiding their pilgrims. Umrah mutawifs need to have performed umrah themselves, obtain teaching credentials fromthe respective states of which they will be teaching and guide, enrich their fiqh of umrah and the basics of farduain, have a good level of health and possess the ability to lead, are among the critical qualifications that must be in place. Finally, this study suggests that, through the enactment or amendment of relevant acts, a regulatorybody need to be established to oversee the regulation and management aspects, among others, of the umrah mutawif. This will ensure the quality and professionalism of umrah mutawif as a respected career in the future could be achieved.
LEVEL OF SATISFACTION ON COMMUNICATION AND LEVEL OF ANXIETY AMONG SUSPECT COVID PATIENTS
Authors:   Lecturer, College of Nursing, Christian Medical College, Vellore, India., Naomi Nancy S.W , Xavier Regina ,   Professor, College of Nursing, Christian Medical College, Vellore, India., Seetharaman Bala ,   Professor, College of Nursing, Christian Medical College, Vellore, India., Khaja Jabin ,   Professor, College of Nursing, Christian Medical College, Vellore, India., Suresh Kumar Alice ,   Professor, College of Nursing, Christian Medical College, Vellore, India.
Published: August 2021

Background: The COVID pandemic has created a huge impact on the emotional level of individuals around the globe. When one is suspected to develop or have the infection, the amount of stress individuals go through is enormous. Communication specially by the health care workers when they are hospitalized will bring a positive impact on their coping. Objectives: The objectives of the study were to assess the suspect COVID patients level of satisfaction on communication, to assess the suspect COVID patients level of anxiety, to find the relationship between the suspect COVID patients level of satisfaction on communication and their level of anxiety, to find the association between the suspect COVID patients level of satisfaction on communication and their demographic variables and to find the association between level of anxiety of suspect COVID patients and their demographic variables. Methods: A correlational study to assess the suspect COVID patients level of satisfaction on communication and their level of anxiety was carried out in the suspect COVID areas of Christian Medical College. Patients who fulfilled the inclusion criteria were recruited using consecutive sampling technique. Patients were given information on the study and informed consent was obtained. Data was collected by interviewing the patients using a Likert scale on the level of satisfaction on communication and the level of anxiety using Hamilton Anxiety Scale. Results: Data was analyzed using descriptive and inferential statistics (SPSS Version 21). Majority of the subjects were found to be between the age group 41 to 60 years. Also, most of them (64%) were male. And around 60% of them had only schooleducation. It was found that 47% of the subjects were found to have mild anxiety and only 41% were highly satisfied with the level of communication. Also, it was proved that as the level of satisfaction on communication increases, the level of anxiety decreases (r=-0.5 at p=0.01). There was also significant association found with education and level of satisfaction on communication (p=0.028) and education and level of anxiety (p=0.017) Conclusion: The findings of this study reveal that we need to develop right communication models in times of pandemics and strategize coping measures that will help individuals going through such crisis.
AN ALTERNATE MODALITY OF STRIPPING OF VARICOSE VEINS
Authors: Stellone Singh Khulem , Chowdary Kothari Midhun , Patankar Shilpa , Bansode Pankaj
Published: August 2021

Varicose veins are very common clinical condition characterised by permanently dilated torturous elongated veins in the leg which is due to incompetence of valves. Risk factors being heredity, occupations of prolong standing, immobility, raised intra abdominal pressure, raised progesterone level, altered oestrogen-progesterone ratio etc. A 27 years old patient with no h/o any systemic disease or co morbidities came with complaints of dilated, tortuous veins in the left lower limb extending from mid-thigh to ankle region since 2 months. Since 1 month the patient was having dull aching pain over the left lower limb on walking and prolonged standing. A thorough clinical examination was done with findings of incompetent Sapheno-femoral junction(SFJ) and perforator incompetence of the left lower limb. A venous Doppler of the left lower limb revealed SFJ dilated and incompetent and Incompetent perforators along the GSV 5 cm below the knee. Following all routine preoperative work-ups, patient was posted for surgery. After ligating all the tributarirs of GSV, while checking the metallic stripper, it snapped in between and was not in a useable condition and there was no other metallic stripper in the OT. Decision had to be taken for an alternative the GSV was sucessfully stripped using a 14F Neltons catheter. Thus as an alternative to metallic stripper, a Neltons catheter can also be used for stripping varicose veins.
ANALYSIS OF THE NEED FOR THE DEVELOPMENT MULTI-REPRESENTATION MODULES TO FOSTER CREATIVE THINKING SKILLS OF JUNIOR HIGH SCHOOL STUDENTS DURING THE COVID-19 PANDEMIC
Authors:   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., Setyowati Dwi , Ketut Mahardika I. ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., Hariyadi Slamet ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121.
Published: August 2021

The purpose of the study was to determine the need for multireperentation modules to foster creative thinking skills in plant structure and function on science learning at junior high school. This research is a qualitative descriptive study. The method used in the online form of questionnaires for teacher and students. Data were analyzed using descriptive analysis and the percentage of the results of the number of answers given was divided by the total number of respondents multiplied by 100%. The results of this study indicate that: (1) 95.56% of teacher need a module as teaching material during COVID-19 Pandemic (2) 97.13% of students like teaching materials that contain multirepresentation (3) The reason of teacher need a multirepresentation module are guide for students in doing learning, facilitating distance learning, overcoming time constraints, making learning systematic and directed, representing the presence of teachers. The conclusion of this research is that it is necessary to develop teaching materials in the form of multireperentation modules to foster creative thinking skills in plant structure and function on science learning at junior high school.
IMPACT OF E-COMMERCE ON EMERGING START-UPS
Authors:   Head, Department of Commerce, Swami Vivekananda First Grade College, Mallur and Research Scholar, Presidency University, Bangalore., K.N Lakshmipathi , Kumar S.V Pradeep ,   Assistant Professor School of Commerce Presidency University. Bangalore.
Published: August 2021

After the 1991, Indian economy witnessed to a change in marketing conditions which are benefit to the development of economy. E-commerce is one of the aspects of changing policies of LPG, Start-ups also another emerging aspect of new policy. The purpose of this research is to understand how e-commerce as sectors brought revolutionary changes in the preference of start-ups. Now a days most of the companies providing services through online, hence it made most of the start-ups to go online because of consumer behaviour is not constant. The study was conducted by collection of primary data as well as secondary data with the help of questionnaires sent through mail among 50 respondents across India. With all background and age grouped into various profession and organisation people. The findings revealed that using e-commerce platform by start-ups are increasing in the last 6 years. Start-ups are trying to shift their trade and services from offline to online system, which means they are using e-commerce websites rather than traditional retail marketing. Time and wide reaching of goods and services are some other factors to using e-commerce to be considered. Start-ups are getting more advantages with e-commerce. I near future e-commerce impact on start-ups are positively increasing not only profit but also countries GDP.
MULTI ORGAN DYSFUNCTION IN A POST-COVID PATIENT - A CASE REPORT
Authors:   MBBS.MD(Clinical Microbiology). Senior Resident, Department of Microbiology, IPGME&R and SSKM Hospital, Kolkata, India., Chakraborty Mohana
Published: August 2021

The typical presentation of SARS-CoV-2 VIRUS infection is pulmonary involvement causing COVID 19 pneumonia. Although in recent times cases are being reported from different hospital that shows multi organ involvement due to COVID-19 virus. Acute pancreatitis is one of the main presentations .here is a case report that shows not only acute pancreatitis but elevated liver enzymes causing non alcoholic liver disease along with gallbladder involvement in a patient who was presented as COVID 19 negative.
RISK FACTORS ASSOCIATED WITH TYPE 2 DIABETES MELLITUS AND THE FREQUENCY OF NAFLD AFFECTED PATIENTS
Authors:   Advance Center for Human Genetics Skims., Ahmed Rehana , Hamed Mahrukh ,   Advance Center for Human Genetics Skims., Khan Nebela ,   Advance Center for Human Genetics Skims., Singh Saurabh ,   Department of Biotechnology Jaipur National University., Rasool Zubaida ,   Department of Pathology Skims., Mushfiq Syed ,   Department of Gastroenterology Skims., Yatoo G.N ,   Department of Gastroenterology Skims.
Published: August 2021

Diabetics have a higher risk of developing nonalcoholic fatty liver disease (NAFLD) and associated complications than the general population. The purpose of this study was to determine the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) in patients with type 2 diabetes, as well as the demographic, metabolic, and biochemical features associated with it. Material and methods: This was a prospective, observational, descriptive (cross-sectional), and non-interventional research on a cohort of type 2 diabetes mellitus patients conducted in a hospital setting. Over the course of 18 months, this study was done (August 2019 to March 2021). Results: A total of 100 patients were enrolled, with 63 (63%) being Females and 64 (37%) being men. Age, BMI, and diabetes duration all had statistically significant positive correlations with the prevalence of nonalcoholic fatty liver disease. Overall prevalence of NAFLD was 63 percent (63/100). In this investigation, gender, age > 48, BMI > 25 kg/m2, and diabetes mellitus duration > 10 years were all risk variables linked with the existence of NAFLD (p=0.0002). Conclusion:Present study highlighted the significant burden of Non-Alcoholic Fatty Liver Disease in cohort of type -2 Diabetes Mellitus. About half of the subjects had NAFLD (63%). In present study high BMI, and duration of diabetes > 10 years were positively correlated with NAFLD.
WHITE CLAY DEPOSITS AT DIFFERENT AREAS OF MADHABPUR AND BAHUBOL UPAZILA, HABIGONJ DISTRICT, BANGLADESH
Authors:   Geological Survey of Bangladesh 153 Pioneer Road, Segunbagicha, Dhaka 1000., Mizanur Rahman Md , Masum Mohammed ,   Geological Survey of Bangladesh 153 Pioneer Road, Segunbagicha, Dhaka 1000.
Published: August 2021

A detail geological investigation was carried out in order to explore white clay deposite at 10 square kilometer areas of Madhabpur and 0.5 square kilometer areas of Bahubal Upazilas in Habiganj District of Bangladesh using hand auger and shallow drilling method. The whole surveyed area was identified for white clay deposits from qualitative as well as quantitative aspect. These deposits were marked at depths from 0.2 meter to 8.0 meter below the surface. Average thickness of white clay at Madhabpur and Bahubol area are 4.0 meter and 5.0 meter, respectively. The estimated reserve of white clay at Madhabpur area is about 68 million tons and that at Bahubal area is 2.8 million tons. Geological investigation suggests that the source rock near Tripura ranges was weathered, transported and deposited as feldspathic sandstone surrounding the present deposition of white clay. Later the sandstone was exposed and much of its feldspar content were weathered to the clay mineral (Kaolinite). Along with white clay peat, peaty clay, sticky clay and silica sand were also observed at depths ranging from 1.5 to 8 meter. Collected white clay samples are yellowish grey to light grey in color and highly compact in dry condition but pasty in wet condition. The dry white clay is soapy to feel, slakes in water, moderately sticky and plastic in nature. Al2O3 content ranged from 25.51 to 27.61% while average SiO2, and Fe2O3 content were found 54.58 and 3.872% respectively. Considering the physical and chemical properties the white clay of the studied area can be considered as moderate to good in quality. This white clay can use in ceramics and other industries. Therefore, this deposit of white clay may help to meet the current national demand and consequently to increase the economic growth.
AYURVEDIC INSIGHTS OF AVASCULAR NECROSIS OF FEMORAL HEAD
Authors:   Ph.D. Scholar, Panchakarma Dept., National Institute of Ayurveda, Jaipur, India., Kumar Surendra , Mangal Gopesh ,   Associate Professor, PG Department of Panchkarma, National Institute of Ayurveda, Jaipur, India.
Published: August 2021

Avascular necrosis of the femur head (AVNFH) is a debilitating disease caused due to the use of alcohol, steroids, following trauma or unclear (idiopathic) etiology, affecting mostly the middle aged population. Clinically AVNFH is associated with impaired blood supply to the femoral head resulting in bone necrosis and collapse.In Ayurveda, there is no direct reference of disease resembling to Avascular necrosis of femoral head, hence it can be understand on the basis of Vikaraprakriti of disease caused by vitiation of Dosa, Adhisthana (abodesite) and Hetu (causes of vitiation of Dosa). In the present study an effort has been made to understand AVN on the ground of Ayurveda.
COMPARISON OF DIFFERENT METHODS OF CENTRIFUGATION FOR OPTIMUM PREPARATION OF PLATELET RICH PLASMA (PRP)& FRAMING A CUSTOMIZED PRP PROTOCOL-AN INNOVATIVE APPROACH
Authors:   Department of Physical Medicine and Rehabilitation, Government Medical College, Pudukkottai, Tamil Nadu, India., Padma Rani S. , Chitrarasu K. ,   Department of Physical Medicine and Rehabilitation, GovernmentKilpauk Medical College,Chennai., Jawahar Rajarathnam S. ,   Department of Physical Medicine and Rehabilitation, GovernmentKilpauk Medical College,Chennai., Thirunavukkarasu P. ,   Department of Physical Medicine and Rehabilitation, GovernmentKilpauk Medical College,Chennai.
Published: August 2021

Introduction:The rationale behind the therapeutic potential of the high concentration of platelets in PRP (Platelet Rich Plasma) for intervention procedures of soft tissue injuries is often challenged by the ability of the centrifugation methods followed in extracting the high quality PRP with prompt contented quantity too.This study aims to unravel the basic science of PRP preparation involved in centrifugation protocols, spin methods, speed and time duration of centrifugation to obtain consistent therapeutic platelets yield. Materials and Methods:30 participants were subjected to intervention procedures using PRP. For therapeutic purpose 3 centrifugation protocol types are followed. ÃƒÂƒÃ‚Â˜ Protocol 1-Conventional Old protocol ÃƒÂƒÃ‚Â˜ Protocol 2-Customised New protocol ÃƒÂƒÃ‚Â˜ Protocol 3-Spin Reversal of the routine -hard spin followed by soft spin The Platelets and WBC concentration and composition in the final autologous PRP sample harvested as a result of double centrifugation method are compared for quantity and efficiency. Results:The maximum PCF-3.21 times above baseline and PRR -64.21% are through new customized spin proving its efficiency. As determined by one-way ANOVA, there is statistically significant difference between the PROTOCOL groups (1,2,3) for the variables PRP platelet count, PRP Leucocytes, PCF, PRR. A Tukey post hoc test revealed that there is statistically significant value for Protocol 2 and Protocol 3 compared to the Protocol 1 for PRP platelet count, PCF and PRR whereas for PRP Leucocytes, there was a statistically significant difference between the Protocol 2 and Protocol 3 which again implicates the necessity of spin reversal in yielding better quantity of leucocytes. Conclusion:To produce PRP samples with consistent and reproducible compositionsof platelets and leucocytes with better quality control standard through a detailed, precise and stepwise description of the manufacturing protocol has been explained in our study. Our perspective is in standardizing a safe, simple protocol that can be followed to obtain an optimal consistent platelet yield without the use of commercial kits, which has been proved statistically too.
A COMPREHENSIVE REVIEW ON THE MAGICAL INDIAN FOLK MEDICINE: PIPER BETLE LINN
Authors:   Senior Research Fellow, Department of Home Science, Laboratory of Food and Nutrition Sciences, University of Calcutta, Kolkata, India., Dutta Suchandra
Published: August 2021

India has rich resources of medicinal plants and their uses in Ayurveda, Unani, and Siddha traditional medicine is quite popular around the world. There are over 2000 medicinal plant species, amongst them, Piper betle Linn. (Paan) is one of the most used ones. It is cultivated mainly in South-East Asia like Vietnam, Srilanka, Pakistan, China and India. Some phytochemical studies have found that betel leaf contains a wide variety of biologically active compounds such as Eugenol, Allylpyrocatechol, Methyl Eugenol, Chavibetol, Hydroxychavicol, Triterpenes and ÃƒÂƒÃ‚ÂŽÃƒÂ‚Ã‚Â²-Caryophyllene. These help in treating many diseases like diabetes, stomach ulcer, cancer, obesity, swelling of gum, malaria, rheumatism, cuts and injuries, etc. This review article is a compilation of traditional, phytochemistry, therapeutic as well as nutraceutical properties of betel leaf based on scientific evidence.
HYDRO-GEL POLYMERS AND 3D BIOPRINTING IN SKIN ENGINEERING - A REVIEW
Authors:   Third year. Amity Institute of Biotechnology Amity University, Noida., C. Raj Anjana
Published: August 2021

Tissue engineering is a booming field of science and technology. The sheer potential it emanates is enough to place all attention on it. Tissue engineering is widely researched for the development of skin substitutes to treat patients with infections or disorders. Commercial skin substitutes provide a promising future to medicine. The availability of different biomaterials for the production of artificial skin has posed many questions regarding the feasibility, usability, and practicality of these products. The articles reviewed discuss tissue engineering as a challenging field and how skin substitutes are vital. Biomaterials and hydrogel studies are found to be a game changer for the field. The functional aspects have been discussed with the physical characteristics for better understanding. Different techniques of printing biological structures by using scaffolds are discussed in detail. Scaffolds provide a very efficient structural composition for the bioprinter to manifest the organ to be printed. Bioink composition and preparation with scientific knowledge make it a very important asset in tissue engineering. The future of regenerative medicine and organ transplantation is expected to be safe within the various aspects of tissue engineering. The vast possibilities it offers is hard to not explore further. Even though the research field has come a long way since the beginning of tissue culture in the 1970s, there are still different challenges to be faced and conquered.
OPTIMISATION OF SOLAR PHOTOVOLTAIC SYSTEM EMPLOYING DISTRIBUTED MPPT CONTROL
Authors:   M.tech Student, Electrical Engineering Department, MMMUT, Gorakhpur, India., Kumar Singh Akash , Pandey A.K. ,   Professor and Head, Electrical Engineering Department, MMMUT, Gorakhpur, India.
Published: August 2021

This paper presents simulation and modeling with optimization and analysis in solar photovoltaic systems, as well as the role and potential of maximum power extraction with controller. Matrix calculations for grid inverters with data graphing, their functions, MPPT algorithm applications, user interface design for monitoring PV modules, and interaction with inverter and converter are all aided by simulations of renewable energy systems. It looks at how well they work on a single-phase grid with a PV system. Simulink model for solar energy conversion systems allows you to examine the performance of Photovoltaic cells, modules, arrays, Maximum Power Points and inverters. Controllers are being tracked when the environment and physical variables change. A distributed MPPT scheme, which allows adjustment of each DC-link voltage, may be adopted for PV systems to achieve maximum PV module usage and solar energy extraction. The pattern that has been developed allows for independent management of each DC-link voltage in order to track the MPP for each string of PV panels. For various operating circumstances, simulation results are provided.
VAGINAL PLATELET-RICH PLASMA ADMINISTRATION TO IMPROVE FEMALE SEXUAL SATISFACTION
Authors: Abdulla Elsayed Mahmoud Mostafa
Published: August 2021

Objective:To investigate the effect of platelet-rich plasma (PRP) injection to the lower one-third of the anterior vaginal wall on sexual function, orgasm, in women with sexual dysfunction by scoring with FSFI. Materials and Methods:Three sessions of PRP (platelet rich human autologous plasma) were administered to the anterior vaginal wall of fiftyfemale patients with sexual dysfunctiondiagnosed by FSFI scoring card obtained in JAM clinic in Benha city Egypt and orgasmic disorder. Female Sexual Function Index (FSFI) total score ÃƒÂ¢Ã‚Â‰Ã‚Â¤26 orgasmic subdomain score ÃƒÂ¢Ã‚Â‰Ã‚Â¤3.75 were considered having sexual dysfunction and recruited in the study. Results:Following the application of the PRP, the total FSFI score was observed as 27.7ÃƒÂ‚Ã‚Â±4.5 and the total score was 26 and above in patients having sexual dysfunction (p<0.001). Orgasm subdomain scores were found as 2.2ÃƒÂ‚Ã‚Â±1.2 before the PRP treatment and 4.4ÃƒÂ‚Ã‚Â±1.06 at the third dose after (p<0.001). Conclusion:PRP administration to the distal anterior vaginal wall improved female sexuality with high satisfaction by using multiple sessions (three month).
AN OBSERVATIONAL STUDY ON THE CONSTRUCTION AND FUNCTIONS OF A WATER CLOCK
Authors:   Supervised by Prof. Norman Lowney., Kataria Dhairya
Published: August 2021

This study examines the workings of a water clock and attempts to formulate alternatives while retaining the basic principles of Torricellis law. There is thorough discussion on the history of water clocks, their different types and the apparatus required to model the functioning prototype. This is followed by a detailed explanation of the procedure undertaken for the construction of the alternate model. In the interpretation and results section, readings and observations measured through 18 different experiments are tabulated through charts and graphs, leading up to a summarized discussion in the conclusion.
A SEVERE STENOSIS OF THE PROXIMAL SEGMENT OF THE LEFT ANTERIOR DESCENDING CORONARY ARTERY PRESENTING WITH AN INFERO-LATERO-BASAL ST-ELEVATION MYOCARDIAL INFARCTION : A CASE REPORT
Authors:   Cardiology Intensive Care Unit, Mohammed V Military Hospital, Rabat, Morocco., Nikiema S. , Lahlafi Z. ,   Cardiology Intensive Care Unit, Mohammed V Military Hospital, Rabat, Morocco., Desire M. ,   Non-Invasive Explorations Department, Mohammed V Military Hospital, Rabat, Morocco., Lakhal Z. ,   Cardiology Intensive Care Unit, Mohammed V Military Hospital, Rabat, Morocco., Benyass A. ,   Non-Invasive Explorations Department, Mohammed V Military Hospital, Rabat, Morocco.
Published: August 2021

A 57-years-old man presented in our department of emergency with an acute chest pain infarct-like. The electrocardiogram realised showed an ST elevation in the infero-latero-basal leads suggesting an occlusion of the right coronary artery or the left circumflex coronary artery. However, the coronary angiography that was performed showed a subocclusion of the proximal left anterior descending coronary artery, in contrast to the expected results. This case was reported using electrocardiography and coronary angiography data and the electrocardiogram changes after a percutaneous coronary intervention. The particularity of this case lies in the lack of correlation between the electrocardiographic Changes and the Coronary Angiographic Findings.
EFFECTS OF GUANIDINOACETIC ACID SUPPLEMENTATION IN BROILER CHICKEN DIET ON CARCASS CHARACTERISTICS
Authors:   Kenyatta University, School Of Agriculture and Enterprise Development Nairobi, Kenya., Chaari Gabriel Ngazi , Kabuage Lucy ,   Kenyatta University, School Of Agriculture and Enterprise Development Nairobi, Kenya., Nguhiu Purity ,   Kenyatta University, School Of Agriculture and Enterprise Development Nairobi, Kenya., Gachuiri Charles ,   Kenyatta University, School Of Agriculture and Enterprise Development Nairobi, Kenya.
Published: August 2021

Guanidinoacetic acid (GAA) is a natural organic acid in the body that acts as a precursor of creatine which plays the role of energy carrier in the cell This study was conducted to determine the effects of supplementing broiler chicken feed with GAA on carcass characteristics. Two hundred-and forty, day old Cornish breeds were kept under a deep litter system. Six treatments with four replicates of 10 birds per replica were used. The experimental diets comprised of six treatments with varying levels of feed additive (GAA) supplemented in the diets D1 (control) with no GAA, D2 was supplemented with (0.003% GAA/kg), D3 (0.006% GAA/kg), D4 (0.009% GAA/kg), D5 (0.012% GAA/kg), and D6 (0.015% GAA/kg). The treatments were laid down in a complete randomized design (CRD) with four replicates. Carcass characteristics were determined in the laboratory by analyzing the (abdominal fat, tissue protein, tissue fat and pH). There were statistically significant effects observed on abdominal fat, body tissue protein and body tissue fat of the carcass. The study concluded that GAA supplementation increased carcass characteristics, and provided better economic returns. The study recommends utilization of GAA supplementation at level of 0.12% GAA/Kg for rapid growth of broiler, enhanced abdominal fat, body tissue protein, body tissue fat, and utilization of GAA for better economic returns to the farmers.
TÜRK-ÇİN SAVAŞLARINDA KİMYASAL SİLAH KULLANIMI
Authors: GÖMEÇ Saadettin Yağmur
Published: August 2021

İnsanlık tarihinin ilk zamanlarında ağaç, taş, kemik gibi alelade nesneleri silah olarak kullananlar, çağlar geçtikçe bunlara yeni biçimler vererek tesirlerini daha da artırmışlardır. Kesici aletler, ok ve yay ile mancınık türü araçların icadı hep bu üstünlük kurma fikriyle alâkalıdır. İnsan karşısındaki rakip aynı silahlarla savaşmaya başlayınca, yeni yollar ve usuller aramaktan da geri durmadı. Bazen toplulukların arasındaki düşmanlık ve nefret öyle bir hale geldi ki, insanlar kendilerinden görmedikleri canlıları külliyen yok etmenin çaresine baktılar. Eski devirlerde bu işi ok ve yay ile yapamayacaklarını, yani karşısındaki on binleri teker teker öldüremeyeceklerini veya bunların sonunu getiremeyeceklerini anladıklarında başka kurnazlıklara yönelindi. Çünkü çoğu zaman kılıç ya da ok yarası tedavi edilip, insanlar kurtulabiliyordu. İşte bu noktada düşmanını toptan imha gayesiyle insan, bir nev’i kimyasal silah diyebileceğimiz zehirleme yoluna gitti.