bluuebunny/crossref_metadata_2025 huggingface dataset:
White Blood Cell and Peripheral Blast Counts in Leukemia Patients with Non-Graying WBC-Diff Scattergram
Authors: Lismayanti Leni , Arif Mansyur
Published: October 2024

Graying scattergram of White Blood Cell differential (WBC-diff) is often accompanied by blasts in the blood and/or leukocytosis in leukemia patients. Therefore, monitoring White Blood Cell (WBC) and peripheral blast count is crucial for patient management. In contrast, patients with non-graying WBC-diff scattergrams may have varying WBC counts and peripheral blasts. This study aimed to establish the cut-off values of WBC and peripheral blast counts that could predict a non-graying scattergram in leukemia patients. A retrospective descriptive study with a cross-sectional design analyzed secondary data from 21 leukemia patients. The acute and chronic leukemia diagnosis were based on bone marrow aspirates, which simultaneously showed a graying WBC-diff scattergram on Complete Blood Count (CBC). Receiver Operating Characteristic (ROC) curve analysis was conducted when the patient’s CBC displayed a non-graying scattergram. The cut-off value for WBC count was 16,380 x 109/L with an Area Under Curve (AUC) of 0.932, a sensitivity of 85.7%, p = 0.001, and the cut-off for peripheral blast count was 35.5% with an AUC of 0.872, the sensitivity of 76.2%, p=0.001. The results suggest that a non-graying scattergram of the WDF channel in leukemia is more likely associated with WBC counts below 16,380 x 109/L and peripheral blast counts below 35.5%, which have excellent and good predictive value.
Antibiotic Susceptibility among Infective Endocarditis Population: Syndromic Antibiogram Evaluation at Indonesian National Cardiovascular Center
Authors: Indrawati Lilik , Sugianli Adhi Kristianto , Prakoso Baskoro Justicia , Gunawan Adrian , Soerarso Rarsari , Soesanto Amiliana M. , Dewi Andaru Dahesih
Published: October 2024

Infective Endocarditis (IE) is a life-threatening disease with a high mortality rate (25%). Laboratory approaches to support the diagnosis of IE especially blood and/or cardiac vegetation culture, are crucial for providing definitive therapy. However, negative culture is frequently observed, therefore empirical use of antibiotics seems unavoidable and may lead to increasing antimicrobial resistance. This study aims to observe the prevalence of antibiotic susceptibility among the IE population using the WISCA approach. This retrospective study observed medical record data of all inpatients diagnosed with IE according to ICD-10 at Cardiovascular Center Harapan Kita Hospital (NCCHK) between January 2018 and December 2022. Patient data were combined with bacterial identification and antibiotic susceptibility test data from the laboratory information system, and evaluated based on period (year). A total of 67,858 inpatients and 1.1% (n=772) were diagnosed with IE. Successful culture growth (blood and/or cardiac vegetation specimen) was between 36.8% and 70% annually. Streptococcus viridans group (82/237, 34.6%) and Coagulase-negative Staphylococci (57/237, 24.1%) were dominantly observed among the IE population. Low susceptibility among Penicillin (34.3%) towards Gram-positive bacteria, as first-line treatment option in IE. Meanwhile, high susceptibility range was observed in Ceftriaxone (95.7%), Gentamicin (80.4%), Rifampicin (84.4%), and Vancomycin (98.7%) as second-line treatment in IE. Despite the low prevalence, the occurrence of antimicrobial resistance in IE has become a priority concern. Continuing the syndromic antibiogram is mandatory to assist the trend of empirical antibiotic usage and refine the established local treatment guidelines.
The Concordance between GeneXpert MTB/RIF and Isothermal Amplification Assay for Detecting Mycobacterium tuberculosis
Authors: Ulfah Nuri Dzulfiani , Andriyoko Basti , Turbawaty Dewi Kartika
Published: October 2024

Tuberculosis (TB) is an infectious disease and one of the biggest causes of death worldwide. The main problem today is the lack of accurate and rapid tests to detect Mycobacterium tuberculosis (MTB). Several molecular methods have been developed to detect MTB. GeneXpert MTB/RIF® can detect MTB and rifampicin resistance simultaneously in <2 hours. Cross Priming Amplification (CPA) is one of the isothermal amplification assay methods that can detect MTB. Both of these methods are molecular rapid tests so they can detect MTB faster. This study aims to evaluate the concordance of GeneXpert MTB/RIF® results with CPA to detect MTB at Hasan Sadikin General Hospital, Bandung. This is an observational cross-sectional study. The subjects were patients with suspected pulmonary TB and examined with GeneXpert MTB/RIF® then CPA (Ustar EasyNAT MTC™) was also examined. This study used total sampling with 50 subjects and analyzed with Cohen's Kappa test. The results of GeneXpert MTB/RIF® and Ustar EasyNAT MTC™ in detecting MTB obtained Kappa of 0.662 (good agreement) with p-value <0.001. Of the 11 low positive samples on GeneXpert MTB/RIF® as many as 6 subjects (54.55%) had positive results, and 5 subjects (45.45%) had negative results on UStar EasyNAT MTC™. Meanwhile, of the 4 very low positive samples, there was only 1 sample with positive results on UStar EasyNAT MTC™. There is a match results between high and medium positive GeneXpert MTB/RIF® and UStar EasyNAT MTC™. However, there is a difference between low and very low positive results on GeneXpert MTB/RIF® and UStar EasyNAT MTC™.
Correlation Analysis between Platelet Aggregation and Neurological Outcomes in Ischemic Stroke Patients
Authors: Nurindar Muyadhil , Muhiddin Rachmawati A. , Muhadi Darwati , Muis Abdul , Nurulita Asvin , Patellongi Ilham Jaya
Published: October 2024

Ischemic stroke is a condition triggered by cerebral perfusion disorders with the risk factor of blood clotting disorders that can cause neurological deficits through a complex pathophysiological process of thrombus formation. The role of platelet aggregation as a blood clotting parameter has the potential to be used as a marker for the level of neurological deficit in patients with ischemic stroke in conjunction with the National Institutes of Health Stroke Scale (NIHSS). The study aimed to observe the correlation between platelet aggregation and the degree of neurological deficit calculated using NIHSS. The study utilized a cross-sectional design with 51 research subjects diagnosed with ischemic stroke based on CT Scan results, followed by platelet aggregation testing. Patients with a diagnosis of hemorrhagic stroke and cardiogenic ischemic stroke were excluded from this study. This study found variations in platelet aggregation among groups with different degrees of stroke severity. However, it was not statistically significant (p=0.427). Correlation analysis showed a mild positive correlation between platelet aggregation and the degree of neurological deficit (r=0.157), although it was not statistically significant (p=0.270). There are variations in platelet aggregation in assessing neurological deficits using NIHSS. There is a positive correlation between the percentage of platelet aggregation and the level of neurological deficit in patients with ischemic stroke.
Relationship between Serum Vitamin D Levels and Asthma Control in Adult Patients
Authors: Sabaruddin Haeriah , Djamaluddin Fauzan , Ilyas Muh. , Iskandar Harun , Lihawa Nurjannah , Nurisyah Siti , Wiriansya Edward Pandu
Published: October 2024

Asthma is a heterogeneous disease characterized by respiratory symptoms that vary both over time and in intensity, along with limited expiratory airflow. This heterogeneity is related to the patient's genetic and environmental phenotype. Vitamin D levels can affect the severity of asthma and the success of asthma treatment. Vitamin D can also influence the effectiveness of glucocorticoid therapy as an anti-inflammatory. This study aimed to determine the relationship between serum vitamin D levels and asthma control, severity, obstruction, and exacerbation levels. This research was a descriptive cross-sectional study on asthma patients at Wahidin Sudirohusodo Hospital and its network for the period October–December 2023. Each research subject had a venous blood sample taken and then checked vitamin D levels at the Hasanuddin University Teaching Hospital Research Laboratory. This research involved 72 research subjects. Most of the research subjects were female (61.1%), aged <45 years (52.8%), worked as housewives (29.2%), had overweight BMI (33.3%), and had a history of atopy (59.7%). The degree of airway obstruction in the study subjects was mostly mild (66.7%) and the degree of severity was intermittent, persistent, and the degree of exacerbation in the same sample (33.3%). The results of the study showed a relationship between vitamin D levels and nutritional status, history of atopy, degree of asthma control using the ACT questionnaire, degree of stable asthma, and exacerbations where p<0.05. Also, it is found that a weakly positive connection (R: 0.2–0.4) between vitamin D levels and ACT, FEV1, FEV/FVC. There is a relationship between vitamin D levels and nutritional status, history of atopy, degree of asthma control using the ACT questionnaire, degree of stable asthma, and exacerbations. There was a relationship between vitamin D levels and the degree of obstruction assessed by spirometry in this study.
Linda index forecast based on ARIMA time series
Authors: Hernández Cesar , Prieto Jesús , Giral Diego
Published: October 2024

Competition in the telecommunications market has significant benefits and impacts in various fields of society such as education, health and the economy. Therefore, it is key not only to monitor the behavior of the concentration of the telecommunications market but also to forecast it to guarantee an adequate level of competition. This work aims to forecast the Linda index of the telecommunications market based on an ARIMA time series model. To achieve this, we obtain data on traffic, revenue, and access from companies in the telecommunications market over a decade and use them to construct the Linda index. The Linda index allows us to measure the possible existence of oligopoly and the inequality between different market shares. The data is modeled through an ARIMA time series to finally predict the future values of the Linda index. The results show that the Colombian telecommunications market has a slight concentration that can affect the level of competition.
Key determinants of digital transformation stages in Vietnam logistics industry
Authors: Thanh Nguyen Nga , Thi Tran Hoa , Van Ta Loi , Nguyen Phuoc Van
Published: October 2024

This research investigates the determinants of digital transformation among Vietnamese logistics service providers (LSPs). Employing the Technological-Organizational-Environmental framework and Resource Fit theory, the study identifies key factors influencing this process across different three stages: digitization, digitalization, digital transformation. Data from in-depth interviews with industry experts and a survey of 390 LSPs were analyzed using covariance-based structural equation modeling (CB-SEM). The findings reveal that the factors influencing the digital transformation of Vietnamese LSPs evolve across different stages. In the initial phase, information technology infrastructure, financial resources, employee capabilities, external pressures, and support services are key determinants. As digitalization progresses, leadership emerges as a crucial factor alongside the existing ones. In the final stage, the impact of these factors persists, with leadership and employee capabilities becoming increasingly important.
SOSYAL BİLGİLER DERSİNDE KAVRAM KARİKATÜRLERİYLE DESTEKLENMİŞ ÖRNEK OLAY YÖNTEMİNİN İLKOKUL ÖĞRENCİLERİNİN FİNANSAL OKURYAZARLIK BECERİLERİNE ETKİSİNİN İNCELENMESİ
Authors: Topcubaşı Tolga , Çelikten Lütfullah
Published: October 2024

Bu çalışmanın amacı, kavram karikatürleriyle desteklenmiş örnek olay yönteminin öğrencilerin finansal okuryazarlık becerilerine etkisini araştırmaktır. Bu araştırma ön test-son test kontrol gruplu yarı-deneysel desene göre tasarlanmıştır. Çalışmada veri toplama aracı olarak, öğrencilerin finansal okuryazarlık tutum ve davranışlarındaki değişimi incelemek amacıyla "Marmara Finansal Okuryazarlık Tutum ve Davranış Ölçeği" kullanılmıştır. Çalışma grubu, kavram karikatürleriyle desteklenmiş örnek olay yöntemini uygulayan deney grubu ve MEB Sosyal Bilgiler programının "Üretim, Dağıtım ve Tüketim" öğrenme alanını işleyen kontrol grubundan oluşmaktadır. Deneysel uygulamalar, nicel verilerin toplanmasıyla birlikte 8 hafta sürmüştür. Çalışmadan elde edilen veriler, SPSS 22.0 paket programı kullanılarak analiz edilmiştir. Çalışmanın verilerinden elde edilen sonuçlara göre, deney grubu öğrencilerinin finansal okuryazarlık tutum ve davranışlarına ilişkin son test puanlarının kontrol gruplarına göre istatistiksel olarak anlamlı bir farklılık gösterdiği tespit edilmiştir. Buna göre, kavram karikatürleriyle desteklenmiş örnek olay yönteminin öğrencilerin finansal bilgilerini artırma ve olumlu finansal tutum ve davranış kazandırma açısından MEB Sosyal Bilgiler öğretim programına kıyasla daha yüksek bir etkiye sahip olduğu görülmüştür.
Determining the Influence of Real Estate Features on Prices with Partial Dependence Plots: A Case Study in Szczecin, Poland
Authors: Gnat Sebastian
Published: October 2024

The study explores the application of Partial Dependence Plots (PDP) in the analysis of real estate features. The study centers on a selected real estate market in Szczecin, Poland, aiming to highlight the efficacy of PDP in understanding and interpreting the complex relationships between various features and property prices. The primary objective is to showcase the potential of PDP in capturing the nuanced interactions between real estate attributes and their impact on market prices. The CatBoost model, known for its robust handling of categorical features and strong predictive capabilities, is employed as the machine learning algorithm for this analysis. The performance of this model will be compared against a traditional multiple linear regression model, providing insights into the advantages of leveraging advanced machine learning techniques in real estate analysis. Results obtained from the analysis will be presented and discussed, shedding light on the interpretability and accuracy of the CatBoost model compared to the traditional linear regression approach. The presentation will conclude with implications for real estate practitioners and researchers, emphasizing the potential for PDP to enhance the transparency and understanding of complex models in the real estate domain. This research contributes to the growing body of knowledge on the application of advanced machine learning techniques in real estate analysis.
Ultrasound Activated Clay: Preliminary Study of PB And as Removal in Aqueous Media
Authors: Pastor-Mina Sofía , Rodriguez-Cardenas Liliana , Guizado Ayde Quispe , Torre Yubher Aderson Vargas , Perez David Oscco , Choque-Quispe David , Ligarda-Samanez Carlos Alberto , Taipe-Pardo Fredy , Carhuarupay-Molleda Yakov Felipe
Published: October 2024

Objective: The objective of this study was to evaluate the removal of Pb and As in aqueous media by activated clay (AC).
 
Theoretical Framework: Heavy metals in water represent a risk to health and ecosystems, their removal through new materials is a challenge for the industry.
 
Method: The methodology adopted for this research comprises in that natural clay (NC) was activated with sodium chloride and phosphoric acid followed by sonication. A synthetic solution of Pb and As was prepared at different pH.
 
Results and Discussion: The zero charge point was found to be 7.10 for AC and 8.02 for NC, the ζ potential was found to be between - 41.15 and - 45.43 mV in the pH range of 4 to 12, with degree of crystallinity of 97.24% and crystal size of 2.85 nm determined by XRD. FTIR analysis allowed the identification of functional groups with chelating capacity. Was observed As removal of 75.51% (110.40 mg/g) and 23.23% (58.13 mg/g) and 97.75% (106.41 mg/g) and 100.0% (206.53 mg/g) for Pb with AC and NC respectively at pH 6 and 8.
 
Research Implications: Los reaultadoe encontrados sugieren que la arcilla activada se convierte en un material alta capacidad de adsorción de metales pesados en sistemas multimetal. Esta cualidad se debe al incremtno de grupos funionales en su superficie y al tamaño nanométrico que incrementa el área de contacto.
 
Originality/Value: Activation of the clay with sodium chloride and weak acid followed by sonication is an environmentally friendly process that produces a material with high heavy metal removal capacity in aqueous media.
Systemic Arterial Hypertension, Diabetes Mellitus and Covid-19: A Retrospective Study in Nineteen Municipalities in Mato Grosso
Authors: Silva Ana Gabryella Vieira e , Silva Giovanna Almeida , Fonseca Jeovana Miranda de Oliveira , Santos Débora Aparecida da Silva
Published: October 2024

Objective: To analyze the prevalence and characteristics of COVID-19 cases in patients with systemic arterial hypertension (SAH) and diabetes mellitus (DM) in the southeastern region of Mato Grosso, between March 2020 and March 2022.
 
Method: Epidemiological and analytical study with secondary data from 19 municipalities in the southeastern region of Mato Grosso from 2020 to 2022. The data are in the public domain from the State's COVID-19 indicator panel. The population included all registered cases of COVID-19 in Mato Grosso, as well as in the municipalities of the southeastern region with SAH and DM as comorbidities. Blank/ignored cases were excluded. The descriptive analysis of the data used frequencies and relative frequencies, with the aid of the R software. Research approved by the Research Ethics Committee (Opinion: 4,418,798).
 
Results: Of the 727,952 cases reported in Mato Grosso, 14.40% occurred in the southeast region, with 14.07% having comorbidities. Among these, 54.11% were hypertensive and 28.18% were diabetic. The profile of hypertensive and diabetic cases, respectively, was predominantly female (55.45% and 54.44%), 51 to 60 years old (25.57% and 27.14%), brown (55.79% and 55.61%), had no cardiovascular problems (77.54% and 72.84%), had no neoplasia (83.38% and 83.28%), were not obese (79.97% and 79.70%), had no lung problems (81.55% and 80.85%), recovered cases (88.74% and 86.96%), were not hospitalized (99.94% and 100%) and had laboratory-confirmed cases (95.95% and 95.69%).
 
Research Implications, Originality/Value: This study highlights the importance of understanding the characteristics of patients with comorbidities and COVID-19 to improve prevention, diagnosis and treatment strategies for the disease.
ANÁLISE DA TOXICIDADE DE ÁGUA SUPERFICIAL DO RIO PARAUAPEBAS, EM PARAUAPEBAS, PARÁ, AMAZÔNIA
Authors: Jesus Rafael Santos de , Ribeiro Hebe Morganne Campos
Published: October 2024

Objetivo: Este estudo objetiva analisar os níveis de metais pesados na água superficial do rio Parauapebas, no município de Parauapebas, Pará, em conformidade com as legislações ambientais CONAMA 357/2005.
 
Referencial Teórico: Baseia-se em estudos sobre contaminação hídrica e seus efeitos em ecossistemas aquáticos, abordando conceitos de toxicidade, bioacumulação de metais pesados e normas ambientais, como a Resolução CONAMA 357/2005.
 
Método: A metodologia adotada é um estudo experimental descritivo com abordagem quali-quantitativa. Amostras de água foram coletadas em quatro pontos estratégicos do rio Parauapebas durante a estação chuvosa de maio de 2024. As análises físico-químicas e de toxicidade foram conduzidas conforme os protocolos do Standard Methods for the Examination of Water and Wastewater.
 
Resultados e Discussão: Os resultados indicaram contaminação por metais pesados como cobre, cromo, ferro, manganês e níquel em níveis acima dos limites permitidos. A condutividade elétrica e a turbidez apresentaram variações significativas, sugerindo influência das atividades humanas. O pH elevado e a temperatura da água também impactaram a solubilidade de substâncias e a atividade biológica. Esses resultados foram discutidos à luz do referencial teórico, destacando a necessidade de políticas rigorosas de gestão ambiental.
 
Implicações da Pesquisa: Esta pesquisa fornece insights práticos e teóricos sobre a gestão de recursos hídricos em regiões afetadas por atividades humanas intensas. As implicações abrangem a necessidade de práticas de mineração sustentável e tratamento adequado de efluentes para preservar a qualidade da água e a saúde pública.
 
Originalidade/Valor: Este estudo contribui para a literatura ao evidenciar os impactos das atividades humanas na qualidade da água do rio Parauapebas e propor medidas de gestão ambiental para mitigar esses efeitos. A relevância deste trabalho está na aplicação dos resultados para melhorar as práticas de gestão de recursos hídricos na região.
The Evaluation of Tifton 68 Production Under Irrigation and Early Nitrogenous Fertilization
Authors: Bonafini Bruno , Faria Dawson José Guimarães , Fraga Júnior Eusímio Felisbino , Parreira Filho Joaquim Martins , Fernandes André Luís Teixeira
Published: October 2024

Objective: To evaluate the effect of the anticipation of nitrogenous fertilization for the winter period, on dry matter production, crude protein content, handling height and productivity in the grasslands of irrigated Tifton 68 grass.
 
Theoretical Framework: Tifton 68 use through years of thorough selection, extensive field testing and careful evaluations culminated in the development of the Tifton 68 cultivar with highly desirable characteristics such as: growth, pest resistance, abundant biomass production and important nutritional quality for the rural producer.
 
Method: A test was conducted in the municipality of Uberlândia, Minas Gerais, for 2 years, with fertilizers carried out in weekly plots on June 21, June 28, July 05, July 12, July 19 and July 26 of the year 2021 to evaluate the performance of the cultivar Cynodon sp cv Tifton 68 with controlled release in vegetative development, as well as the impacts of this technology of sizing on its performance and productivity.
 
Results and conclusion: Anticipation of nitrogenous fertilization in the Cynodon sp cv culture of Tifton 68 had a statistical difference for productivity (g/m²) in year 1 with the best fertilization 234 kg/ha, being the treatment that most closely approximates the result is T4. Anticipation of nitrogenous fertilization was not statistically significant for Height, dry matter content and crude protein.
 
Implications of the research: With the results of the research, it was possible to identify the positive factors of the use of nitrogenous fertilizers in the controlled release for culture Cynodon sp cv of Tifton 68, so many in the aspects of strengthening biomass and added nutritional value in forage.
 
Originality/value: a better understanding of the effects of the appropriate use of fertilization on the cultivar Cynodon sp cv Tifton 68, both in the biometric and productive generating economic and environmental performance in agribusiness.
FORTALECIMIENTO DE LA RELACIÓN DE LAS PYMES DEL SECTOR AGRO CON EL SISTEMA NACIONAL DE INNOVACIÓN AGROPECUARIA DE ANTIOQUIA-COLOMBIA
Authors: Marín Correa Juan Felipe , Enciso Eliana María Villa , Cortés Alejandro Silva , Casadiego-Alzate Rodolfo
Published: October 2024

Objetivo: identificar las estrategias para fortalecer las capacidades de innovación y articulación de las Pymes del sector Agro con el Sistema Nacional de Innovación Agropecuaria (SNIA) en Antioquia, Colombia.
 
Marco Teórico: El fundamento teórico se sustenta en el reconocimiento de la tierra como factor generador de riqueza, componente estratégico de desarrollo y sostenibilidad territorial asociada a los ámbitos agrícola, forestal, pecuario y pesquero.
 
Método: Revisión Sistemática de la Literatura con análisis estadístico descriptivo de datos; se utilizó diferentes bases de datos: SCOPUS, E-Libro.Net, Science Direct, EBSCO, Ministerio de agricultura, DANE, plataforma economática, Banco Mundial y la FAO.
 
Resultados y Discusión: se revelaron una serie de estrategias de articulación que se deben implementar en el sector para su fortalecimiento como: a) Identificación de las capacidades desde lo técnico, operativo y financiero para sostener los procesos de producción, b) identificación de las demandas desde las cadenas de suministro, entre otras.
 
Implicaciones de la investigación: Se demuestra que es necesario la artículación del sector con el SNIA, realizando un fortalecimiento integral de la competitividad, la disminución de las brechas en los sistemas productivos,  la activación de la extensión agropecuaria y fortalecimiento del sector.
 
Originalidad/Valor: Este estudio contribuye a la literatura y es relevante porque identifica estrategias utilizadas, brechas existentes y establece prácticas de articulación de las Pymes con el Sistema Nacional de Innovación Agropecuaria de  Colombia. La relevancia y valor de esta investigación se evidencian em la importancia del sector agropecuario para garantizar no sólo la seguridad sino también la soberanía alimentaria de la región y por ende del pais.
Debittering Process of Lupin (Lupinus albus l.) by Ultrasound Pre-treatment
Authors: Baltacıoğlu Cem , Özcan Tarım Asiye
Published: October 2024

Bu çalışma, acı baklanın (Lupinus albus L.) acılığı giderme sürecinde bir ön işlem yöntemi olarak ultrasonun etkinliğini araştırarak, genel kalitesini ve besin profilini iyileştirmeyi amaçlamaktadır. Acı bakla tohumları protein ve diğer temel besin maddeleri bakımından bol miktarda bulunur, ancak başta acı bakla ve lupinidin olmak üzere acı alkaloidler içerirler ve bu da bunların gıda ve yem olarak kullanılmasında zorluklar yaratır. Geleneksel acılık giderme yöntemleri, zaman alıcı olan ve besin kayıplarına yol açabilen suya batırmayı içerir. Ultrason, besin bütünlüğünden ödün vermeden acılık giderme sürecini hızlandırma kabiliyeti nedeniyle umut verici bir alternatif olarak ortaya çıkıyor. Bu araştırmada, acılık giderme verimliliğini optimize etmek için acı bakla tohumlarına çeşitli koşullar altında ultrason ön işlemi uygulandı. Ultrason gücü, işlem sıcaklığı ve süresi gibi parametreler, alkaloitlerin uzaklaştırılması ve besin içeriğinin korunması üzerindeki etkilerini belirlemek için sistematik olarak değerlendirildi. Ön işleme tabi tutulmuş Lupin numuneleri daha sonra alkaloit konsantrasyonları, protein içeriği ve diğer besin özelliklerindeki değişiklikler açısından analiz edildi. Uygulanan ultrason destekli ekstraksiyon yöntemi yeni bir bakış açısı getirmiş ve ısıtma işlemi ultrasonla uyarlanarak acılık giderme işlemi daha kısa sürede gerçekleştirilmiştir. Ön sonuçlar, acı bakla tohumlarındaki acılık seviyelerini ve alkaloid konsantrasyonlarını azaltmada ultrason ön işleminin etkinliğini göstermektedir. Üstelik süreç, Lupin'de bulunan temel besin maddelerini korur ve böylece insan tüketimi ve hayvan yemi için değerli bir protein ve diğer besin kaynağı olma potansiyelini artırır. Bu çalışma Lupin için sürdürülebilir ve verimli ön arıtma yöntemlerinin geliştirilmesine katkıda bulunarak gıda, yem ve çeşitli endüstriyel uygulamalarda daha geniş kullanımının yollarını açıyor.
The Nexus between Cluster Farming and Household Dietary Diversity among Smallholder Wheat Farmers in Ethiopia
Authors: Bezabeh Ali Addisu , Lemma Tefera Tesfaye
Published: October 2024

This study examined the nexus between cluster farming and household dietary diversity among smallholder wheat farmers in Oromia region, Ethiopia. Three-stage sampling procedures were employed to gather data from 384 household heads on a cross-sectional survey that was carried out in June 2022. Descriptive statistics and a binary logistic regression model were used for data analysis. The average, minimum, and maximum household dietary diversity scores were 7.10, 1, and 11, respectively. A significant difference was observed: participants in cluster farming had 14% more dietary diversity than their counterparts. Sex, marital status, participation in wheat cluster farming, home gardening, off-farm income, number of crops grown, cooperative membership, and access to training determined household dietary diversity. The study indicates that dietary diversity in households is influenced by a variety of factors. While wheat cluster-based farming is heavily promoted, household food and nutrition security also need to consider other elements like home gardening, off-farm income, cooperative membership, and training access.
Comparative Evaluation of Enzymatic Crude Protein Degradation in Selected Legume Forages
Authors: Oral Hülya Hanoğlu
Published: October 2024

For protein evaluation of feedstuffs for ruminants, the Streptomyces griseus protease test offers a purely enzymatic approach to estimate ruminal protein degradation. This study was conducted to determine the enzymatic crude protein (CP) degradability of alfalfa, sainfoin, and common vetch hays, which are commonly used in ruminant nutrition. To estimate CP degradation, fifteen samples from each type of hay were incubated in vitro with a commercial protease extracted from Streptomyces griseus. The incubation was carried out for 1, 4, 24, and 48 hours in a borate-phosphate buffer at pH 8. Significant differences in CP degradability values were found among all three types of hay across all incubation periods. For all incubation periods, sainfoin had the lowest CP degradability values (P < 0.05), due to its high content of cell wall components and condensed tannins (CTs). For incubation periods longer than 1 hour, common vetch had the highest CP degradability values, followed by alfalfa and sainfoin, respectively (P < 0.05). As a result, the use of the protease enzyme extracted from Streptomyces griseus was confirmed as an effective method for estimating the CP degradability of selected legume forages in the laboratory, eliminating the need for animal testing. However, since plant proteins are often embedded within carbohydrate complexes, it is recommended that future tests consider the combined use of protease and carbohydrase, particularly for sainfoin, which is rich in cell wall components and condensed tannins.
Effects of Dietary Microalgae Schizochytrium sp. Supplementation on Growth Performance and Skin Color in Jack Dempsey cichlid (Rocio octofasciata)
Authors: Karataş Boran , Kaya Doğukan
Published: October 2024

Growth retardation and decreased vivid coloration are significant issues in the ornamental fish market, particularly among cichlids. This study investigates the effects of Schizochytrium sp. microalgae supplementation on the growth and skin coloration of the Jack Dempsey cichlid (Rocio octofasciata). Three experimental groups were established: a control group (C) with no supplementation, and two microalgae-supplemented groups with 0.5% (S05) and 1% (S10). The control group was fed a commercial diet, while the S05 and S10 groups received the microalgae mixed with the commercial feed via spraying. A total of 135 Jack Dempsey fish (mean initial weight: 1.17 ± 0.14 g) were stocked into nine glass tanks (100 L each), with three replicates per group. After a 60-day feeding trial, growth indices revealed significant differences (p<0.05) between the control and algae-supplemented groups. The S10 group exhibited the highest final weight (FW) and the lowest feed conversion ratio (FCR). Additionally, the weight gain (WG) and specific growth rate (SGR) values for the S10 group were significantly higher than those of both the control and S05 groups (p<0.05). However, skin color parameters, including L* (brightness), a* (+red/-green axis), b* (+yellow/-blue axis), chroma (Ch), and hue angle (Hue), showed no statistical differences among the groups. This study demonstrates that a diet supplemented with 1% Schizochytrium sp. can enhance growth parameters and serve as a beneficial feed additive for Jack Dempsey cichlids.
A Gastronomic Approach to Industrial Aquaculture Waste Utilization
Authors: Dikel Suat , Dikel Çiğdem
Published: October 2024

Aquaculture, while offering significant contributions to global food security, generates substantial amounts of industrial waste, posing environmental and economic challenges. However, this waste also presents untapped potential for innovation in gastronomy. This paper explores the emerging trend of utilizing aquaculture industrial wastes in culinary practices, aiming to reduce waste, promote sustainability, and create novel gastronomic experiences. Through a review of literature and case studies, we examine various methods for repurposing aquaculture waste, including upcycling into new food products, incorporation into culinary dishes, and extraction of valuable components. Additionally, we highlight successful initiatives that have integrated aquaculture waste into gastronomy, emphasizing the benefits of waste reduction, sustainable food practices, and culinary innovation. Challenges such as food safety, taste, and consumer acceptance are acknowledged, with strategies proposed for addressing these issues. Finally, we discuss future directions for research and development in this field, identifying opportunities for collaboration between the aquaculture industry and the gastronomy sector. By exploring the utilization of aquaculture industrial wastes in gastronomy, this paper contributes to a deeper understanding of sustainable food practices and culinary creativity in the context of aquaculture waste management.
Exploring the Causal Relationship between Plasma Lipidome and Allergic Diseases: A Mendelian Randomization Study
Authors:   Southwest Medical University, Liu Qiang
Published: October 2024

Allergic diseases, including Allergic Rhinitis (AR), Allergic Asthma (AA), Allergic Conjunctivitis (AC), and Allergic Contact Dermatitis (ACD), affect a significant portion of the global population. Recent advances in lipidomics have highlighted the role of plasma lipids in immune regulation and inflammation.
Artificial Intelligence Applications for Diagnosis and Differentiation of Vestibular Disorders
Authors:   ASL Frosinone, Raponi Ingrid
Published: October 2024

The objective of this work lies in leveraging recent advances in Artificial Intelligence to enhance the diagnosis and treatment of vestibular disorders, crucially improving patients' conditions and their overall quality of life.
Fa‘atama: Indigenous Tomboys of Sāmoa
Authors: Treagus Mandy , Enari Dion
Published: October 2024

This paper acknowledges that queerness has always existed in the tropics, especially in Sāmoa. In traditional Sāmoan life, there has always been more than two genders. While much attention has been given to fa‘afafine, we seek to raise the visibility of another queer group, fa’atama (formally fa‘atane) or tomboys—Sāmoans assigned female at birth (AFAB), who either identify as masculine, are attracted to females, or both. Not only is this group marginalised on the world stage, but also within Sāmoan and Pacific culture, which has suppressed their lives and identities. In the context of a very specific historical and cultural milieu, we examine three recent representations—in poetry, fiction, and film—of queer AFAB Sāmoans in order to privilege their stories.
Queering Tropically: Sexuality, Indigeneity, Decoloniality, Spatiality
Authors: Benitez Christian Jil R. , Chwala Gregory Luke , Lundberg Anita
Published: October 2024

This is the second collection of papers in a two-part issue on the theme of Queering the Tropics. This second issue begins by delving into the notion of “Queering Tropically,” in other words, queering in a tropical manner or in the manner of the tropics. The term queering tropically simultaneously alludes to queering through tropes (figurative and performative), and queering through tropical materiality (climate, elements, nature). This issue asserts that the tropics has always been a space where queerness lives, not a place where queerness has arrived post colonialism; queerness was and is often recognized as part of nature in the tropics. This assertion is evident in discussions of Sexuality, Queer Indigeneity, and Decoloniality. Furthermore, Queering the Tropics in attending to the queer across the worldly zone of the tropics is inherently a spatial practice. The tropics, as the Other of the temperate zone, has been subjected to waves of colonialisms and their patriarchal and heteronormative power structures. Yet, the tropics subverts and inverts the structures and strictures of the temperate zone, and this Tropical Queer Spatiality opens up to myriad ways of queer being and becoming. Thus, the papers collected together in this special issue offers a richness that furthers queer studies.
Aerothermal Loads on a Representative Porous Mesostructure at Flight Conditions Using Direct Simulation Monte Carlo
Authors: Kroells Michael , Ramjatan Sahadeo , Schwartzentruber Thomas E.
Published: October 2024

Spacecraft require thermal protection systems (TPS) in order to survive the extreme conditions present during atmospheric entry missions. Porous ablators are a class of TPS materials that have been used successfully on several entry missions, although they can be difficult to model because of their complex nature at the micro- and mesoscales. Specifically, the processes that lead to mechanical erosion (spallation) of these materials are poorly understood. In order to gain insight into the spallation process, the current work computes aerothermal loads on a mesostructure representative of FiberForm (the substrate of phenolic impregnated carbon ablator) by leveraging a simulation framework involving loosely coupled Computational Fluid Dynamics-Direct Simulation Monte Carlo (CFD-DSMC) simulations of hypersonic boundary layers. CFD boundary layers are extracted from two altitudes, 68.9 and 81 km, along the Stardust entry trajectory and are imposed as boundary conditions on a DSMC simulation over an artificially generated mesostructure, which is representative of the charred layer of the TPS material. In order to produce high-quality results, the DSMC boundary conditions require careful consideration; specifically, Chapman–Enskog distributions are needed to account for large velocity and temperature gradients. Visualizations of the DSMC flowfield indicate excellent agreement with the original CFD data, and the aerothermal loads (heat flux and traction force) on the surface were examined using probability density functions. Additionally, the effects of pyrolysis blowing through the mesostructure on the surface properties are also determined.
Finansal Başarısızlık Risk Tahmini: Madencilik ve Taş Ocakçılığı İşletmeleri Üzerine Bir Uygulama
Authors: Katı Murat
Published: October 2024

Ülke ekonomilerinde yaşanan gelişmeler, teknolojik gelişmeler, ekonomik krizler ve salgın hastalıklar finansal başarısızlık kavramını önemli hale getirmiştir. Mikro ve makro düzeyde yaşanan değişimler ve gelişmeler işletmelerin finansal yapılarını etkilemektedir. İşletmelerin sürdürülebilirliklerini sağlamak adına değişen koşullara ve ortaya çıkabilecek risklere karşı önlem almaları gerekmektedir. Bu kapsamda çalışmanın amacı, Borsa İstanbul’da (BİST) madencilik ve taş ocakçılığı sektöründe faaliyet gösteren işletmelerin finansal başarısızlık risklerinin tahmin edilmesidir. Çalışma kapsamında madencilik ve taş ocakçılığı sektöründe faaliyet gösteren işletmelerin 2017-2023 yıllarına ilişkin finansal tabloları Kamuyu Aydınlatma Platformu (KAP) internet sitesinden temin edilerek analize tabi tutulmuştur. Çalışmada yer alan işletmelerin finansal başarısızlık riskleri, risk tahmin yöntemlerinden Altman ZI Skor Modeli, Springate ve Fulmer Modelleri kullanılarak tespit edilmiştir. Çalışmanın sonucunda işletmelerin finansal başarısızlık durumlarının modeller ve yıllar itibariyle farklılık gösterdiği tespit edilmiştir. Daha sonraki çalışmalarda farklı sektörlerin çalışma kapsamına alınması, çalışma döneminin genişletilmesi veya Beaver, Ohlson, Zmijeswki ve Canada gibi diğer finansal başarısızlık tahmin modellerinin kullanılması sunulacak öneriler arasındadır.
“Quiet Quitting” as a New Trend in the Labor Market
Authors: Radko E. D.
Published: October 2024

One of the brightest phenomena of recent years in the labor market has become “quiet quitting”. It has been described in Russian and foreign publications. At the same time, this subject is poorly covered in the Russian scientific literature. The purpose of this study is to analyze the phenomenon of “quiet quitting” as a trend in the modern labor market, to summarize the theoretical provisions of this. Thus, this article defines “quiet quitting” as a form of employee behavior with low engagement and focus on performing the required minimum of work duties. The author emphasizes that although the nature of this phenomenon is not new, it has become widespread in recent years, largely due to several reasons, both inside the organization (corporate culture, quality of management, etc.) and outside it. Since “quiet quitting” became widespread in the post-pandemic period, the study pays special attention to the impact of the pandemic that catalyzed it. In addition, it reveals the generational characteristics of attitudes to work and career, and explains the propensity to “quiet quitting” of young people. The author concludes that “quiet quitting”, being a trend of recent years in labor markets in many countries, is part of a broader process of transformation of traditional forms of employment, reassessment of the place of work and career in life, which can be both related to the generational change as a source of labor resources and a consequence of a pandemic. Further research could focus on developing specific recommendations for combating or adapting to “quiet quitting” and more in-depth study of country differences in this phenomenon.
Oral cavity squamous cell carcinoma complicated by internal jugular vein thrombosis
Authors: Verma Ashish Kumar , Sahoo Anjan Kumar
Published: October 2024

Head and neck squamous cell carcinoma (SCC) encompasses various cancers from the upper aerodigestive tract. Initial presentation often includes regional nodal involvement (40% in stage IVA or B) and distant metastases (up to 10%). Facial edema is a frequent clinical issue with multiple causes, such as allergic reactions, trauma, venous thrombosis, infections, and both benign and malignant conditions. An extremely rare condition is tumor thrombosis of the internal jugular vein (IJV), typically reported in differentiated thyroid cancer cases. We present a diagnosed case of SCC of the left lower alveolus in a 54-year-old female who presented with diffuse facial swelling and stridor two years post-diagnosis. Further evaluation through clinical examination and imaging studies revealed partial thrombosis of the right IJV. The patient underwent an emergency tracheostomy and was treated with intravenous heparin, which effectively managed the local symptoms. This case report highlights the clinical features, diagnostic methods, treatment modalities, and favorable prognosis associated with the long-term effects of untreated head and neck cancers.
Liberalizmde Hobbes: Gerilim ve İkilikler
Authors: Ayhan Türkbay Rezzan
Published: October 2024

Liberalizm, modern bir ideoloji olarak ortaya çıktığı dönemden itibaren çeşitli koşullara uyarlanarak varlığını sürdürmektedir. Liberalizmin, temel argümanları sabit kalmakla birlikte, günümüze dek birçok düşünce ve ideolojiye eklemlenmesi onu türdeş olmayan bir teori haline getirmiştir. Çeşitli ölçütler çerçevesinde yapılan tartışmalarda liberalizm, farklı iyi hayat anlayışlarına ilişkin olarak genellikle iki ana eksen içinde değerlendirilmiştir. Bir tarafta, içeriği değişen yorumlara maruz kalabilen belli bir iyi hayat anlayışını liberalizmin zorunlu koşulu olarak kabul eden kapsamlı liberalizm ekolü; diğer tarafta ise farklı iyi hayat anlayışlarının bir arada yaşayabileceği çerçeve arayışı içinde olan siyasal liberalizm ekolü yer almaktadır. Modern dünyada farklılıkların belirginleşmesiyle liberalizmin meşruluğunun sorgulanması ve liberalizme yönelik eleştirilerin artması iki eksen arasında gerilim ve çelişkileri artırmıştır. Thomas Hobbes liberal düşüncenin henüz doğmadığı ama tarihsel olarak öncüllerinin oluştuğu bir dönemde eserlerini vermiş olmasına rağmen liberalizmin meşruluk arayışlarındaki kritik meseleler açısından oldukça önemlidir. Bu çalışmada, Hobbes ve liberalizm arasındaki ilişkinin ele alınma amacı, Hobbes’un liberalliği ve liberalizmin iki ana ekseni içindeki konumu tartışmalarının, liberalizmin kendi gerilim ve ikiliklerinin analizine imkân sağlamasıdır. Bu analiz, metodoloji, bireycilik, güvenlik-özgürlük denklemi, sözleşme düşüncesi ve tarafsızlık temaları üzerinden yapılmıştır.
К проблеме границ правового суверенитета в космосе
Authors: Головина А.А.
Published: October 2024

В настоящей статье рассматриваются проблемы определения границ правового суверенитета государств в космосе, в том числе исторические корни установления современной правовой модели освоения космоса, актуальные попытки пересмотреть некоторые устоявшиеся постулаты в отношении правовых границ в космическом правовом пространстве, связанные с принятием отдельными странами собственных законов о присвоении добытых в космосе полезных ископаемых, а также делаются выводы о возможных перспективах распространения концепции суверенитета на космическое правовое пространство по мере дальнейшего развития технологий его освоения.

This article examines the problems of determining the boundaries of the legal sovereignty of states in space including the historical roots of establishing a modern legal model of space exploration, current attempts to revise some established postulates regarding legal boundaries in outer space with the adoption of individual countries of their own laws on the appropriation of minerals mined in space and also draws conclusions about possible prospects for the spread of the concept of sovereignty and the space legal space with the further development of technologies for its development.
Применение в Китае системы уголовного урегулирования в отношении несовершеннолетних
Authors: Чжан Ц. , Ли С.
Published: October 2024

В отличие от Запада китайский Уголовно-процессуальный кодекс в системе уголовного урегулирования не имеет соответствующих положений в отношении несовершеннолетних преступников. Очевидно, что это не способствует возвращению несовершеннолетних правонарушителей на правильный путь социальной интеграции. В данной статье проведен анализ современного применения в Китае уголовного урегулирования в отношении несовершеннолетних, вскрыты многочисленные его недостатки, предлагается усовершенствовать систему уголовного урегулирования в Китае в отношении несовершеннолетних правонарушителей в пяти аспектах.

In contrast to the West the Chinese Criminal Procedure Code in the criminal settlement system does not have relevant provisions for juvenile offenders, in practice often follows the generally accepted criminal settlement. Obviously, this does not contribute to the return of juvenile offenders to the right path of social integration. In this article based on the meaning of the application of a criminal settlement in relation to juvenile offenders an analysis of the modern application in China of criminal settlement in relation to juvenile offenders is made and many shortcomings are revealed . This article proposes to improve the system of criminal settlement in China in relation to juvenile offenders in five aspects: in conditions, areas, range of participants, period of time and appropriate support mechanisms.