bluuebunny/crossref_metadata_2025 huggingface dataset:
Emancipación y autenticidad: el lugar del ser humano en las filosofías de Heidegger y el joven Marx
Authors: Montero Felipe
Published: June 2024

El propósito de este artículo es examinar en conjunto las filosofías del segundo Heidegger y del joven Marx para mostrar cómo, aunque difieren en algunos aspectos importantes, ambas filosofías están motivadas por preocupaciones similares y no son tan diferentes como para impedir un diálogo productivo entre ellas. En la medida en que puede decirse que ambos pensadores han pensado, tomando la palabra en el sentido heideggeriano, lo "mismo", el modo en que ambas filosofías divergen entre sí puede ser especialmente esclarecedor a la hora de ofrecer una interpretación clara de las mismas (una tarea especialmente importante para lograr una comprensión de la filosofía de Heidegger que a menudo resulta oscura). Veremos cómo la noción de finitud de Heidegger implica una serie de críticas a la filosofía de Marx. Por último, plantearé una pregunta sobre los límites de la crítica de Heidegger a Marx, considerando que esta crítica llega a criticar la idea de que todos los seres humanos son iguales e implica un rechazo de la idea de los derechos humanos.
Chronic consequences of ischemic stroke: Profiling brain injury and inflammation in a mouse model with reperfusion
Authors: Murphy Devin P. , Dickson Denali C. , Fatema Arisha N. , Carrasco Nolan G. , Doyle Kristian P. , Trouard Theodore P. , Morrison Helena W.
Published: June 2024

Stroke is a pervasive and debilitating global health concern, necessitating innovative therapeutic strategies, especially during recovery. While existing literature often focuses on acute interventions, our study addresses the uniqueness of brain tissue during wound healing, emphasizing the chronic phase following the commonly used middle cerebral artery (MCA) occlusion model. Using clinically relevant endpoints in male and female mice such as magnetic resonance imaging (MRI) and plasma neurofilament light (NFL) measurement, along with immunohistochemistry, we describe injury evolution. Our findings document significant alterations in edema, tissue remodeling, and gadolinium leakage through MRI. Plasma NFL concentration remained elevated at 30 days poststroke. Microglia responses are confined to the region adjacent to the injury, rather than continued widespread activation, and boron‐dipyrromethene (BODIPY) staining demonstrated the persistent presence of foam cells within the infarct. Additional immunohistochemistry highlighted sustained B and T lymphocyte presence in the poststroke brain. These observations underscore potentially pivotal roles played by chronic inflammation brought on by the lipid‐rich brain environment, and chronic blood–brain barrier dysfunction, in the development of secondary neurodegeneration. This study sheds light on the enduring consequences of ischemic stroke in the most used rodent stroke model and provides valuable insights for future research, clinical strategies, and therapeutic development.
Boussinesq's equation for water waves: Asymptotics in Sector I
Authors: Charlier Christophe , Lenells Jonatan
Published: June 2024

In a recent study, we showed that the large

(

x
,
t

)

\left(x,t)

behavior of a class of physically relevant solutions of Boussinesq’s equation for water waves is described by ten main asymptotic sectors. In the sector adjacent to the positive

x

x

-axis, referred to as Sector I, we stated without proof an exact expression for the leading asymptotic term together with an error estimate. Here, we provide a proof of this asymptotic formula.
Blood self-sampling devices: innovation, interpretation and implementation in total lab automation
Authors: Poland Dennis C.W. , Cobbaert Christa M.
Published: June 2024

The introduction of the vacuum tube in 1949 revolutionized blood collection, significantly improving sample quality and patient comfort. Over the past 75 years, laboratory diagnostics have evolved drastically, from manual to automated processes, reducing required test volumes by over 1,000 times. Despite these advancements, venous blood collection presents logistical challenges, including centralized scheduling and a large volume of biological waste due to the imbalance between the needed blood volume (often very little) and the collected volume (often in excess). The COVID-19 pandemic further emphasized the need for decentralized healthcare solutions and patient empowerment. Capillary blood collection, widely used in point-of-care testing, offers a promising alternative, particularly for patients facing frequently, or difficulties with, venous sampling. The Leiden University Medical Center in the Netherlands experienced a 15 % reduction in volume of laboratory tests during and after the pandemic, attributed to patient preference for local blood collection and testing. To address these challenges, self-sampling devices are emerging, empowering patients and streamlining sample logistics. However, challenges such as cost, transportation regulations, and sample volume adequacy persists. Robust devices tailored for total lab automation and sustainable practices are crucial for widespread adoption. Despite hurdles, the integration of self-sampling into diagnostic processes is inevitable, heralding a shift towards patient-centered, proactive healthcare. Practical recommendations include robust device design, ease of use, affordability, sustainability, sufficient quality and acceptability by seamless integration into laboratory workflows. Although obstacles remain, self-sampling represents the future of laboratory diagnostics, offering convenience, cost-effectiveness, interoperability and patient empowerment.
Fast analysis approach for instability problems of thin shells utilizing ANNs and a Bayesian regularization back-propagation algorithm
Authors: Nguyen T. N. , Zhang Dongsheng , Singhatanadgid Pairod
Published: June 2024

This research develops a data-driven methodology for structural instability problems with highly nonlinear, difficult, noisy, and small data. A fast analysis and prediction (FAP) approach for instability problems of thin shells is first proposed. This approach contains two phases: the fast numerical analysis and the pure prediction utilizing artificial neural networks (ANNs) incorporated with the Bayesian regularization (B-R) algorithm as follows: (1) in Phase 1 (the fast numerical analysis), post-buckling analysis is conducted utilizing a minor amount of load steps. The load–displacement relation achieved from Phase 1 is not exact because of the small number of load steps utilized; (2) in Phase 2 (the prediction), the loads and deflections achieved from Phase 1 were employed as the data for training ANNs. The trained networks, including the load and displacement networks, were employed to fast predict loads and deflections at any step of the post-buckling analysis. After utilizing Phase 2, a smooth, complete and exact load–displacement curve was achieved. In Phase 1, the available formulation for post-buckling analysis of thin shells in the literature was utilized. Five popular types of instabilities chosen to confirm the effectiveness and exactness of the FAP were snap-through, snap-back, softening–hardening, kink instabilities, and delamination buckling and post-buckling of composites. The high exactness and effectiveness of the FAP were confirmed in the numerical verification section. The present approach saves a huge computation compared to the other ones. It was found that ANNs incorporated with the B-R algorithm have notable advantages compared to numerous neural networks. The proposed approach is applicable to simulations or experiments where data are “expensive”, highly nonlinear, difficult, and limited. Utilizing the proposed approach for these fields can dramatically save time and money.
Plastic-free, oil- and water-resistant paper for food packing
Authors: Li Peiyi , Zhou Xinyao , Jian Boxing , Zhou Miaomiao , Liu Ruiyan , Sun Bolong , Li Xinping , Wang Yun , Zhou Bingyao
Published: June 2024

Traditional food packaging coated paper is not environmentally friendly, and there have been many studies on oil- and water-resistant paper for food packaging. However, preparing oil- and water-resistant paper that is plastic-free, fluorine-free, and environmentally friendly is still a significant challenge. In this study, oil- and water-resistant paper for food packaging are prepared by layer-by-layer assembly and mixing coating methods. The layer-by-layer assembly coated paper exhibits excellent water resistance (Cobb 60 value of 20.5 g/m2, water contact angle value of 132°). The mixed coated paper not only has good water resistance (Cobb 60 value of 27.1 g/m2, water contact angle value of 131°), but also has excellent oil resistance (kit rating value of 8/12). The oil-resistant and waterproof mechanism of the coated paper is confirmed through scanning electron microscopy. In addition, the mechanical performance and coating adhesion of the mixed coated paper are the best, with an increase in the tensile index of 73.1 %. This study provides a feasible strategy for preparing biodegradable, plastic-free, and fluorine-free food packaging oil- and water-resistant paper, which is beneficial for reducing plastic pollution.
Energy harvesting and ANFIS modeling of a PVDF/GO-ZNO piezoelectric nanogenerator on a UAV
Authors: Astan Nasrollah , Mohammadzamani Davood , Gholami Parashkoohi Mohamad , Ebrahimi Ebrahim
Published: June 2024

The aim of this study is to energy harvesting and modeling from a soft and flexible nanogenerator based on nanofibers (PVDF/ZnO-RGO) on the arm of a multi-rotor UAV. The nanogenerator modeling was done to improve the usability of piezoelectric nanogenerators to provide part of the electric energy required by drones. Tests were conducted on the experimental setup and practical flight conditions. In each test and a period of 30 s, the vibration signals of the UAV arm were stored, and the vibration data extracted in the time domain and the electrical voltage of the nanogenerator were obtained through the vibrations of the drone, and its values were recorded in each experiment. After signal processing, the best vibration features were used for modeling. In the modeling process, some data were considered for training and testing in ANFIS network. The ANFIS inputs included the selected vibration features and the outputs included the stored voltage. The modeling results were analyzed based on increasing the amplitude of vibrations and the duration of exposure of the nanogenerator to vibration led to higher voltage generation. The maximum voltage recorded during the 30-s flight time of the tested UAV was 64 mV at 3.54, 49.8, and 0.48 Hz along the x, y, and z axes, respectively. The results showed that the application of energy harvesting on different vibration systems could be improved through modeling. It can be used to predict the amount of electric energy produced according to the vibrations of the drone in the future.
Separation studies of 60Co (II) and 134Cs (I) radionuclides from aqueous solution using starch-grafted citric acid-acrylamide/magnesia hydrogel
Authors: Youssef Maha Ali , Dakroury Gehan Abdel Rahman Sadek , Hassan Hisham Soliman
Published: June 2024

In this study, three starch hydrogels composite prepared using different ratios of starch, citric acid, acrylamide, and MgO nanoparticles (referred to as St1-g-(CA-AM), St2-g-(CA-AM), and St3-g-(CA-AM) MgO). These materials were assessed using FT-IR, SEM, and EDX. The adsorption of 134Cs(I) and 60Co (II) onto these materials studied using radiometric analysis. The investigation focused on how temperature, contact duration, initial metal ion concentration, and pH of the solution affected the sorption efficiency. It is found that a pH value of 7 optimized the adsorption reaction, reaching equilibrium after 40 minutes. The kinetics of the adsorption followed a pseudo-second order model. The Langmuir model adequately explained the sorption mechanism, supported by the analysis of isotherm models. The monolayer adsorption capacities for 60Co (II) and 134Cs (I) were 113.38 and 100.2 mg g−1, respectively. The thermodynamic study indicated that the sorption process is both endothermic and spontaneous.
Crisis and curfew: Lived experiences of community members seeking emergency maternal and neonatal care before and during the COVID-19 pandemic on Mfangano Island, Lake Victoria, Kenya
Authors: Mattah Brian , Singaraju Marali , Pande Elias , Ogola Evance , Benard Gor , Otieno Scholarstica , Odhiambo John , Dusek Alex , Deslauriers Nick , Chikamai Lavinah , Muldoon Lily , Ndunyu Louisa , Salmen Charles
Published: June 2024

Prior to the COVID-19 pandemic, families in rural sub-Saharan Africa faced numerous well-documented barriers in accessing timely care during maternal and neonatal health emergencies. We are now beginning to further appreciate the complex impacts that global disruptions, like the COVID-19 pandemic, can have on access to maternal care across vulnerable health systems, particularly for mothers seeking care in remote settings. In 2021, we initiated a qualitative follow-up study to the MOMENTUM (Monitoring Maternal Emergency Navigation and Triage on Mfangano) cohort study conducted within the remote communities of Mfangano Island on Lake Victoria, in Western Kenya, in 2019 and early 2020. Given the timing of this follow-up study, we sought to further qualify the barriers previously identified during the initial MOMENTUM quantitative survey, as well as explore specific ways that the COVID-19 pandemic impacted these barriers. In September 2021, 4 Focus Group Discussions (FGDs), with a total of 44 participants, were conducted among patients and families who had recently experienced maternal and neonatal emergencies. Additionally, 15 Key Informant Interviews (KIIs) were conducted with community leaders and health-care providers to allow reflection more broadly on their local emergency health-care system. A grounded theory methodology was utilized to analyze respondent themes. The lived experiences reported here by FGD and KII participants substantiate and validate numerous challenges previously identified in our prior study. Importantly, participants also highlighted specific ways that the pandemic intensified each of these factors, through the spread of misinformation, restricted mobility due to government curfews and lockdowns, increased frequency of health worker strikes, and worsening financial and resource constraints across the health system. Participants also described creative ways in which contextually experienced providers (i.e., Mfangano Health Navigators) facilitated critical coordination to help patients access care during the chaotic circumstances generated by the pandemic. These findings suggest that trained community health workers can play an influential role in improving emergency care coordination, particularly during future pandemics and similar public health disruptions within extremely resource-limited environments.
Dual role of valosin-containing protein (VCP/p97) in mouse sperm during capacitation
Authors: Jabloñski Martina , La Spina Florenza A , Schiavi-Ehrenhaus Liza J , Marín-Briggiler Clara I , Gomez-Elias Matias D , Krapf Dario , Visconti Pablo E , Krapf Diego , Luque Guillermina M , Buffone Mariano G
Published: June 2024

Valosin-containing protein (VCP; aka p97), a member of the AAA (ATPases Associated with various cellular Activities) family, has been associated with a wide range of cellular functions. While previous evidence has shown its presence in mammalian sperm, our study unveils its function in mouse sperm. Notably, we found that mouse VCP does not undergo tyrosine phosphorylation during capacitation and exhibits distinct localization patterns. In the sperm head, it resides within the equatorial segment and, following acrosomal exocytosis, it is released and cleaved. In the flagellum, VCP is observed in the principal and midpiece. Furthermore, our research highlights a unique role for VCP in the cAMP/PKA pathway during capacitation. Pharmacological inhibition of sperm VCP led to reduced intracellular cAMP levels that resulted in decreased phosphorylation in PKA substrates and tyrosine residues and diminished fertilization competence. Our results show that in mouse sperm, VCP plays a pivotal role in regulating cAMP production, probably by the modulation of soluble adenylyl cyclase activity.
Usos connotativos e intencionales del discurso en español formulado en primera persona del plural. Análisis pragmático e inferencial
Authors: Portillo Fernández Jesús
Published: June 2024

La presente investigación analiza los usos connotativos e intencionales del discurso en español formulado en primera persona del plural. Presentamos un estudio pragmático e inferencial que toma como punto de partida el origen etimológico de los pronombres personales de primera persona, la revisión diacrónica de las investigaciones de mayor impacto sobre deixis, la distinción entre usos inclusivos y exclusivos de la primera persona del plural y la carencia de marcas morfológicas en el español actual para diferenciar dichas características. Analizamos la alteración de la autoría / responsabilidad, la singularidad, la implicación afectiva, la participación real o ficticia, la representación, la asimilación de coordenadas vitales, el ejercicio de la patria potestad, la externalización del lenguaje interior y la redefinición del eje deíctico a partir de los usos marcados de la primera persona del plural.
TURGA LAGERSTÄTTE (MIDDENDORF’S OUTCROP, EASTERN TRANSBAIKALIA, BARREMIAN-APTIAN): STRATIGRAPHIC RANGE AND PALAEOENVIRONMENTS
Authors: КОСЕНКО И.Н. , ПЕЩЕВИЦКАЯ Е.Б. , ЕФРЕМЕНКО В.Д. , МЕТЕЛКИН Е.К. , ЯН П.А. , РОДЧЕНКО А.П. , НИКИТЕНКО Б.Л. , МИРЗАБАЕВ Д.А.
Published: June 2024

На основании изучения фауны и микрофоссилий возраст тургинской свиты в обнажении Миддендорфа определен как конец баррема-начало апта. Состав комплексов фауны и палиноморф позволяет коррелировать тургинскую свиту с формацией Yixian и низами формации Jiufotang Северо-Восточного Китая. Результаты петрографического и геохимического анализов, а также изучения микрофоссилий показали, что отложения накапливались в мелководном озере со спокойной гидродинамикой, иногда в условиях дефицита кислорода. По составу спорово-пыльцевых комплексов восстановлены климатические условия (умеренно теплый климат, переходный к субтропическому) и тип растительности (хвойные леса с примесью лиственных пород).

The age of the Turga Formation in the Middendorf’s outcrop is determined as latest Barremian-earliest Aptian based on fauna and microfossil assemblages. The composition of the fauna and palynomorph assemblages allows correlations between the Turga Formation and the Yixian Formation and lower part of the Jiufotang Formation of Northeast China. Results of the petrographic and geochemical analysis as well as microfossil studies showed that sediments accumulated in a shallow lake with low-energy hydrodynamics, sometimes under low-oxygen conditions. Climate features (warm temperate climate transitional to subtropical) and type of vegetation (coniferous forests with admixture of hardwoods) are reconstructed taking into consideration the composition of spore-pollen assemblages.
STRATIGRAPHY AND SEDIMENTOGENESIS OF THE CLINOFORM UPPER JURASSIC OF THE ANABAR-LENA SEDIMENTARY BASIN (ARCTIC SIBERIA, LAPTEV SEA COAST)
Authors: ДЕВЯТОВ В.П. , НИКИТЕНКО Б.Л.
Published: June 2024

Представлены новые материалы по стратиграфии и особенностям строения бат-неокомских разрезов Анабаро-Ленского бассейна. На территории, прилегающей к Таймырской горно-складчатой системе, выявлено клиноформоподобное строение верхнеюрских толщ, отличающихся большой мощностью по сравнению со смежными разрезами востока этого региона. Предложен лектостратотип чернохребетнинской свиты (верхи нижнего оксфорда-низы волжского яруса). Составлен наиболее полный и непрерывный стратиграфический разрез, приведены его лито- и хроностратиграфические корреляции с разрезами сопредельных территорий, детально охарактеризованных комплексами фоссилий, обосновано новое литостратиграфическое расчленение территории, уточнено фациальное районирование отложений, составлена схема мощности толщ верхов бата-бореального берриаса Хатангско-Оленекского междуречья.

New materials on the stratigraphy and structural features of the Bathonian-Neocomian sections of the Anabar-Lena basin are presented. In the territory adjacent to the Taimyr mountain-folded system, a clinoform-like structure of the Upper Jurassic strata has been revealed, which are characterized by high thickness compared to adjacent sections in the east of this region. The lectostratotype of the Chernokhrebetnaya Formation (uppermost Lower Oxfordian-lowermost Volgian) is proposed. The most complete and continuous stratigraphic section is compiled, its litho- and chronostratigraphic correlations are given comparing to the sections of adjacent territories characterized in detail by fossil assamblages. The evidences for a new lithostratigraphic division of the territory are provided, facies zoning of sediments is clarified, a thickness chart of the Upper Bathonian-Boreal Berriasian strata of the Khatanga-Olenek interfluve is proposed.
TOWARDS STAGE SUBDIVISION OF THE VENDIAN
Authors: ГРАЖДАНКИН Д.В. , АЛЕКСАНДРОВ Д.О. , МАКСИМЕНКО В.О. , РОГОВ В.И.
Published: June 2024

Путь к ярусному расчленению венда должен лежать через составление полного сводного геологического разреза этого отрезка земной коры - последовательности геологических тел, каждое из которых отражает определенное состояние экосистем. В качестве основы ярусной шкалы венда предлагается использовать сводный разрез венда Сибирской платформы, представляющий собой последовательность геологических тел регионального и субглобального масштаба, каждое из них отражает определенное состояние либо однонаправленное изменение геосистемы, обусловленные периодическим проникновением на шельф обстановок, относительно насыщенных кислородом, в перерывах между широкомасштабными океанскими событиями аноксии и эвксинизации. Вариации окислительно-восстановительных условий должны были сопровождаться переменной доступностью питательных веществ, что не могло не сказаться на общем характере макроэволюционных и макроэкологических процессов. Геологическая летопись венда Сибирской платформы также свидетельствует о периодическом ощелачивании Мирового океана. В сводном разрезе венда Сибирской платформы различаются, по крайней мере, пять таких событий, с которыми связывается ощелачивание. Предлагается гипотеза, согласно которой событийное ощелачивание могло стать причиной наблюдаемой периодичности в появлении и исчезновении специфических осадочных текстур в карбонатных отложениях, дискретного характера раннедиагенетической цементации алюмосиликокластических осадков и фоссилизации остатков мягкотелых организмов в венде.

The way towards the stage subdivision of the Vendian starts with the assemblage of a complete composite geological section of this interval of the Earth’s history, a succession of geological bodies each reflecting a certain ecosystem state. A Vendian composite section of the Siberian Platform, which is a succession of regional to sub-global scale geological bodies reflecting particular states or unidirectional transformations determined by episodic expansion of relatively oxygen-rich environments onto the shelf and alternating with large-scale oceanic anoxia and euxinia events is proposed as a reference for constructing the stage subdivision of the Vendian. The redox instability had to be accompanied by changes in nutrient availability and could not but affect the course of macroevolution and macroecology. The geological record of the Vendian of the Siberian Platform is also marked by episodic increase in alkalinity of the World Ocean. At least five such alkalinity events could be provisionally identified in the composite section of the Vendian of the Siberian Platform. A hypothesis is proposed suggesting that the alkalinity events could control the appearance and disappearance in the geological record of a distinctive suite of sedimentary structures in carbonates, the discrete nature of early diagenetic cementation of aluminosilicoclastic sediments, and fossilization of soft-bodied organisms in the Vendian.
A case of a linear foreign body removal in a miniature companion pig
Authors: Smith Joe , Cain Alison , Kirkpatrick Jordan , Breuer Ryan , White Robin , Murphy Morgan
Published: June 2024

Despite the recent rise in popularity of miniature pigs as companion animals, there are few published reports available regarding gastrointestinal surgery in these animals. This case report describes a 4-year-old castrated male companion potbellied pig who was diagnosed with a small bowel linear foreign body and associated pyloric outflow obstruction. A gastrotomy and three enterotomies involving the proximal and mid-jejunum and proximal centripetal loop of the spiral colon were performed to remove the linear foreign body. The surgical techniques and post-operative care described in this case report provided effective treatment of the linear foreign body and adequately prevented clinical evidence of post-operative complications in the companion potbellied pig. Follow-up information was obtained via telephone interviews and a recheck appointment one year later revealed a healthy animal with no abdominal radiographic or ultrasonographic abnormalities.
Harnessing poultry slaughter waste for sustainable pet nutrition: a catalyst for growth in the pet food industry
Authors: Kumar Rishav , Goswami Meena
Published: June 2024

Dogs, renowned for their social nature and versatile roles in human society, necessitate proper nutrition to maintain health and vitality. With the burgeoning pet food market in India driven by increasing poultry production, there exists an opportunity to address environmental concerns while advancing companion animal nutrition. Currently, disposal of inedible poultry byproducts poses environmental challenges, urging a shift towards sustainable practices. This paper advocates for the utilization of poultry slaughter waste in pet nutrition, highlighting its nutritional benefits and environmental implications. By recycling poultry waste into valuable sources of animal proteins, minerals, and vitamins, the pet food industry can meet the dietary needs of companion animals while mitigating environmental pollution. Furthermore, the incorporation of animal byproducts aligns with carnivores' natural dietary instincts and addresses the limitations of plant-based protein sources. Drawing from established practices in industrialized nations, this paper underscores the potential of poultry slaughter waste utilization to propel the growth of the pet food industry in India. Embracing this sustainable approach not only ensures the well-being of companion animals but also fosters economic development and environmental stewardship in the Indian context.
Nutrition in Alzheimer’s disease
Authors: Rudzińska Anna Karolina
Published: June 2024

Dementia in Alzheimer’s disease leads to the loss of independence and the onset of disability, which, combined with the deficits common in old age, creates a barrier to maintaining good nutritional status and represents a risk factor to the development of malnutrition. The aims of this synthesis were to collect data on the role of diet in the prevention of dementia and discuss the appropriate nutrition for patients at different stages of Alzheimer’s disease. In addition, the study aimed to provide an overview of methods for assessing nutritional status to allow the selection of an appropriate management strategy for patients with dementia. Findings on the role of diet in dementia prevention have identified certain dietary patterns that can be considered beneficial. The article also discusses the European Society for Clinical Nutrition and Metabolism (ESPEN) guidelines published in 2015, which address nutritional care for dementia patients. These include recommendations for dietary assessment, dietary modifications, and nutrient supplementation. An important aspect of the article is the subject of dysphagia, which affects a significant number of Alzheimer’s disease sufferers. The paper highlights selected recommendations for dietary modification from the European Society for Swallowing Disorders (ESSD) and the European Geriatric Medicine Society (EuGMS).
Peramalan Kerapatan Air Laut (Densitas) Selama Dua Belas Hari Menggunakan Model Regresi: Studi Kasus Laut Timor.
Authors: Asmoro Nuki Widi , Pranowo Widodo Setiyo , Aji Tri , Rahmatullah Amri
Published: June 2024

Laut Timor adalah salah satu perairan strategis yang penting untuk kegiatan pelayaran kapal selam. Informasi akurat tentang nilai densitas di perairan Laut Timor masih sangat terbatas dan sulit dilakukan secara tepat. Penelitian ini menggunakan 6 stasiun observasi yang dianggap mewakili daerah penelitian untuk melihat karakteristik sekitar daerah penelitian. Penelitian ini bertujuan untuk mengestimasi nilai densitas air laut di Laut Timor dengan regresi linear menggunakan data model Copernicus Marine Environment Monitoring Service (CMEMS) sebagai variable independent dan data in situ World Ocean Database (WOD) sebagai variable dependent di lapisan permukaan, lapisan thermocline dan lapisan dalam. Komputasi yang digunakan untuk menentukan nilai densitas menggunakan persamaan TEOS-10 UNESCO yang telah diinstall di Ocean Data View (ODV) dan hasilnya digunakan untuk pembangunan persamaan regresi menggunakan modul Analysis Toolpak yang telah diinstall di Microsoft excel. Data yang digunakan meliputi posisi, kedalaman, salinitas, suhu pada kedalaman tertentu, kemudian dilakukan forecasting model secara statistika untuk memprediksi densitas air laut di Laut Timor selama 12 hari di lapisan permukaan, lapisan Termoklin dan lapisan  dalam. Penelitian ini penting karena nilai densitas laut yang akurat sangat diperlukan dalam mendukung pelayaran kapal selam, terutama dalam hal navigasi dan keseimbangan hidrostatik. Hasil penelitian ini berupa nilai forecasting estimasi nilai densitas pada 3 lapisan kedalaman pada lapisan permukaan nilai tertinggi 1.021,8 kg/m³ dengan nilai rata-rata MAPE 0,25% dan lapisan Termoklin densitas tertinggi 1.024,79 kg/m³ dengan nilai rata-rata MAPE 1,65% dan laut dalam densitas tertinggi 1.032,30 kg/m³ dengan nilai rata-rata MAPE 0,021%. Diharapkan bahwa penelitian ini dapat memberikan kontribusi positif dalam pengembangan ilmu pengetahuan -oseanografi di Laut Timor.
Status on management of access to genetic resources, traditional knowledge and benefit sharing
Authors: Hien Le Thi Thu , Ha Nguyen Hai , Hang Pham Le Bich , Anh Ta Thi Kieu
Published: June 2024

The management of access to genetic resources, traditional knowledge (TK), and benefit sharing among indigenous people and local communities in the worldwide is extensively addressed in international legal instruments, including the Convention on Biological Diversity (CBD) and its Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits (ABS) Arising from their Utilization. The CBD aims to promote the conservation of biological resources, the sustainable use of biodiversity components and the equitable, fair sharing of benefits arising from the use of genetic resources. The Nagoya Protocol sets out core obligations for its contracting Parties to take measures in relation to ABS and compliance. In 2021, the Secretariats of the CBD released the first draft of the Post-2020 Global Biodiversity Framework with the mission for the period up to 2030, aiming towards the 2050 vision: “To take urgent action across society to conserve and sustainably use biodiversity and ensure the fair and equitable sharing of benefits from the use of genetics resources, to put biodiversity on a path to recovery by 2030 for the benefit of planet and people.” Therefore, capacity building and development for the implementation of the Nagoya Protocol are crucial, especially for developing countries. One of the most commonly identified new capacity building needs is digital sequence information on genetic resources and their roles in ABS.
As a member of the CBD and the Nagoya Protocol, Vietnam has obligations to develop the National Strategy Framework on Biodiversity to 2030, with a vision to 2050, consistent with the requirements of the Post-2020 Global Biodiversity Framework, Protocols, and relevant Agreements. This includes developing recommendations on management of access to genetic resources and TK, as well as benefit sharing within the Draft of the National Biodiversity Strategy and Action Plan. This research aims to contribute to implement the Post-2020 Global Biodiversity Framework and the Nagoya Protocol in Vietnam by assessing the status of management regarding access to genetic resources, TK, and benefit sharing.
Construction of the RNAi plasmids to suppress the expression of chitin synthase-encoding genes (chs) in fungus Mucor lusitanicus
Authors: Mai Le Ngoc , Duc Luu Minh , Quang Dang Minh , Trung Trieu Anh
Published: June 2024

Mucormycosis is an emerging fungal infection caused by many species belonging to the order Mucorales. The lack of effective therapies to treat this disease is due to our limited understanding of its pathogenesis. Chitin is one of the fungal-specific components of the cell wall. In fungi, chitin synthase and chitin deacetylase are the key enzymes involved in chitin biogenesis. The RNAi mechanisms have been well-studied in the fungus Mucor-lusitanicus, a model organism for mucormycosis studies. The RNAi technique has been previously applied to study gene function. In this study, two chitin synthase-encoding genes (chs1 and chs2) were identified using transcriptomic data. Approximately 1 kb of DNA fragments of the target genes were amplified and cloned into the pMAT1812 vector to generate the corresponding RNAi plasmids. Initial screening by colony PCR identified 3/10 and 1/10 potential colonies that might contain the RNAi plasmids. One plasmid for each clone was selected and named pAT63 and pAT64, corresponding to the chs1 and chs2 genes, respectively. The validation of these recombinant RNAi plasmids using different restriction enzymes (NotI - PvuII and SalI - PstI for plasmids pAT63 and pAT64, respectively) showed the expected results. The DNA sequencing of the plasmids pAT63 and pAT64 using specific primers validated the results of the screening process. These RNAi plasmids can be used to suppress the expression of the target genes. The silencing mechanism of the target genes will be triggered by the expression of the RNAi plasmids. This approach allows us to study the function of the chitin synthase-encoding genes in this fungus.
Choose Your Own Research Adventure: An Asynchronous Tutorial to Address “Research as Inquiry”
Authors:   University of California, Irvine, Brinkman Stacey , Hilton Samantha ,   Occidental College
Published: June 2024

The Framework for Information Literacy for Higher Education posits that the practice of asking questions in order to deepen inquiry and understanding is a key element of information literacy. While the “Research as Inquiry” frame is teachable in library instruction, it can be difficult to scale. Popular instructional design software tends to present information in linear formats that can limit how students understand the iterative nature of research. This article presents an attempt at an asynchronous tutorial that overcomes this limitation of medium and that presents “Research as Inquiry” through an iterative and question-based online game. We discuss the development, implementation, and assessment of the tutorial, as well as issues of sustainability and scale.
Анализ динамики развития Калининградского рынка туристических услуг
Authors:   Доктор политических наук, Турция, Burak Ahmet
Published: June 2024

Tourism affects the enrichment, increase, and build-up of cultural potential, ensures harmony of relations between different states and ethnic groups, forces authorities, public, and social organisations, including commercial companies, to actively participate in the problem-solving of preserving the environment and improving its ecological level. The paper’s aim is to identify the factors determining demand for tourist services and the economic analysis of the tourism sector in Kaliningrad.
„Biada temu domowi, gdzie żona przewodzi mężowi...” – przegląd praw kobiet w państwach islamskich
Authors:   Uniwersytet Opolski, Banaś Agnieszka
Published: June 2024

This article deals with the rights of women in the Muslim world according to the Koran and the principles of Sharia law. In many areas, these rights are not respected, denied, or removed. Many women do not know their rights, believing their fathers and husbands, trusting in the eternal book, the Koran. However, changes in the legal field have been taking place since the 19th century thanks to women activists fighting to improve the lives of other Muslim women.
Niektóre aspekty rozwoju polskiego i czeskiego ruchu robotniczego
Authors: Wiktor Zbigniew
Published: June 2024

The cooperation of Polish and Czech communists on the Sudeten Borderland has been going on for many years, it has had various stages and intensities. The most diverse and massive one was in the period of the Polish People’s Republic and socialist Czechoslovakia, when it included not only individual and family contacts. The mass cooperation included workplaces, schools, universities and other colleges, local government bodies, and numerous social organisations. It contributed to overcoming numerous, often negative, stereotypes among Poles and Czechs. Later, after the introduction of martial law in Poland, it collapsed. Political changes came and the borders were opened again, but today, it is no longer massive and organised. Individual and sometimes family contacts dominate, cross-border trade is flourishing, e.g., Czechs willingly come to the markets in Kudowa, Kłodzko, etc. On the other hand, Poles are willing to take up jobs nearby and more distant Czech workplaces. An interesting phenomenon of this cooperation are various meetings and party-political events undertaken on the Czech border by Polish and Czech communists, as well as representatives of other left-wing social organisations. This manifests itself in regular visits (usually twice a year), participation in mutual events, e.g., on the occasion of May 1, Liberation on May 8–9, as well as in active participation in socio-political, historical, and other conferences. There is also systematic mutual information on the Internet, exchange of magazines, posters, even participation in international events in the Giant Mountains, Trutnov, Hradec Králové, and even Prague. Czech comrades pay visits to the Polish side of the border. They are interested in the further development of events in our country. Recently, Polish comrades have taken the stand for the Czech candidate of the Central Committee of the Communist Party of the Republic who was persecuted by the regime and who, along with two other comrades, was put in the dock of a court in Prague and convicted of the alleged “Katyn lie”. Other issues of the article concern the analysis of the historical background of Polish-Czech relations in the distant and recent past.
RISK FACTORS AT NON-UNION OF TIBIAL FRACTURE TREATED WITH INTRAMEDULLARY NAIL
Authors: Puccetti Vitor Lorens Yulta Abe , de Miranda Fernando Loureiro , de Figueiredo Caio Cesar Nogueira , Medeiros Kayo Augusto de Almeida , Leonhardt Marcos de Camargo , Silva Jorge dos Santos , Kojima Kodi Edson
Published: June 2024

ABSTRACT Objective: Identify the predictors associated with delayed union at 6 months and non-union at 12 months in tibial shaft fractures treated with intramedullary nailing (IMN). Methods: This retrospective longitudinal study included a cohort of 218 patients who sustained tibial shaft fractures and received IMN between January 2015 and March 2022. We gathered data on a range of risk factors, including patient demographics, trauma intensity, associated injuries, fracture characteristics, soft tissue injuries, comorbidities, addictions, and treatment-specific factors. We employed logistic bivariate regression analysis to explore the factors predictive of delayed union and non-union. Results: At the 6-month follow-up, the incidence of delayed union was 28.9%. Predictors for delayed union included flap coverage, high-energy trauma, open fractures, the use of external fixation as a staged treatment, the percentage of cortical contact in simple type fractures, RUST score, and postoperative infection. After 12 months, the non-union rate was 15.6%. Conclusion: the main predictors for non-union after IMN of tibial shaft fractures are related to the trauma energy. Furthermore, the initial treatment involving external fixation and postoperative infection also correlated with non-union. Level of Evidence III; Retrospective Longitudinal Study.
Gastric content technique collection for in vitro degradation and gas production in horses supplemented with live yeast and protected yeast
Authors: Pombo G.V. , Pereira Y.S. , Mazzo H.C. , Franzan B.C. , Pimentel V.S. , Alves G.E.S. , Faleiros R.R. , Oliveira A.P.L. , Paz C.F.R. , Gobesso A.A.O.
Published: June 2024

ABSTRACT Due to the difficulty in acessing certain sites of fermentation and possible starch digestion, studies show the need for equine gastric digestive fisiology evaluation. The aim of this experiment was to assess horses supplemented with live yeast and protected live yeast (Saccharomyces cerevisae NCYC Sc 47) to validate a new procedure of gastric content collection for determination of pH, latic acid, short chain fatty acids and gas production and degradation to be used in further in vitro fermentative studies. The experimental design used was a the latin square (4x4) for 4 periods and 1 day of gastric content collection, with 15 days of rest between it. The groups were divided in control (CTRL), non protected live yeast (NPYEA), protected live yeast (PYEA) and a combination of live yeast + protected yeast (COMB). Treatment means were compared using orthogonal contrasts (C1: CTRL versus NPYEA, PYEA and COMB; C2: COMB versus NPYEA and PYEA; C3: NPYEA versus PYEA) and Tukey´s test was used at a 5% significance level. The procedure was highly tolerated and provided great accuracy of the collection site. The live yeast supplementation increased the concentration of acetic acid at the horses’ stomachs. When gastric content was used as inoculum for in vitro fermentation, the protected live yeast produced less gas.
Precision and trajectory of three-dimensionally printed animal-specific drill guide for cervical transpedicular screw placement in dogs: An ex vivo study
Authors: Sargı L.F. , Rocha T.A.S.S. , Dıssenha A. , Sobrınho F.B. Silva , Gonçalves Neto J.A. , Dias L.G.G.G. , Mınto B.W.
Published: June 2024

ABSTRACT The aim of this study was to evaluate the precision of a new surgical drill guide model printed in 3D to assist in directing cervical transpedicular screw placement. Five canine cadavers underwent computed tomography (CT). C5 and C6 cervical vertebrae were exported to three-dimensional (3D) reconstruction software, which allowed the creation of an animal-specific virtual perforation surgical guide (3DSDG) based on the safe corridor of the vertebral pedicle for placement of 2.7 mm screws. The 3DSDG were printed in 3D by the SLA method. Pedicular screws were applied with the aid of the 3DSDG in cadaveric vertebrae (specimens) and ABS-printed biomodels. After implantation, a CT scan was performed on the specimens and biomodels, the images were exported to a program to assess the transverse angle of the perforations. There was no difference between the screw trajectories angles in the species (p >0.05) and biomodels (p >0.05). The evaluation of screw trajectories by the three-dimensional reconstruction method and by computed tomography also showed no significant differences (p >0.05). Our hypothesis was confirmed once the 3D-printed animal-specific drill guide can potentially help guide the drill for screw drilling in the caudal cervical vertebral pedicle in dogs.
Temporal trend and magnitude of previdenciary benefits for workplace accidents in Brazil
Authors: Santos Júnior Claudio José dos , Fischer Frida Marina
Published: June 2024

ABSTRACT Objective: To analyze the temporal trend and magnitude of national indicators of previdenciary benefits for workplace accidents issued and granted by the Social Security of Brazil. Methods: Secondary data from Social Security from 2008 to 2019 were used. The trend and percentage variation of the indicators were estimated through Prais-Winsten generalized linear regression. Results: A total of 9,220,372 previdenciary benefits for workplace accidents were issued by the Social Security of Brazil in the period, costing approximately R$ 8.4 billion and representing about 2.0% of the net value of all benefits paid. None of the categories of previdenciary benefits for workplace accidents showed an increasing trend. The highest variation in the benefits granted and issued for workplace accidents occurred in temporary disability benefit (B91), with an annual percentage variation of -54.00% and -29.29%, respectively. Conclusion: A reduction in magnitude and an overall decreasing trend were observed in the historical series of national indicators of benefits granted and benefits issued related to workplace accidents in Brazil from 2008 to 2019.
Contribuições dos Saberes Indígenas para a Reterritorialização da Psicologia Social
Authors: Almeida Simone Alves de , Carvalho Rejane Nunes de , Silva Rosane Azevedo Neves da
Published: June 2024

Resumo Objetivo Este artigo propõe repensar a psicologia social a partir dos saberes indígenas, considerando que eles interrogam as políticas de subjetivação derivadas da concepção binária de natureza e cultura que fundamenta a modernidade. Método Trata-se de um artigo teórico que analisa as contribuições indígenas para a descolonização do pensamento psicológico, considerando o contexto das mudanças climáticas. É problematizada a abrangência do que se entende como social, assim como a quem a subjetividade é atribuída ou não na psicologia. Resultados A psicologia reproduz as dicotomias ocidentais ao basear-se numa natureza fixa, externa a si, cujo social é concebido a partir do excepcionalismo humano. Para os povos que compreendem a vida como efeito de relacionalidades entre seres humanos e não-humanos, essas categorias não fazem o menor sentido. Conclusão A complexidade dos saberes e o protagonismo indígena frente às lutas por terra e território num contexto de mudanças climáticas apontam para a urgência de reterritorialização da psicologia social.
Prevalence and clinical characterization of oral clefts in patients with chromosome trisomy 18
Authors: Martinez Nadini Cristina Marins , Almeida Sheila Tamanini de , Rosa Rafael Fabiano Machado , Zen Paulo Ricardo Gazzola
Published: June 2024

ABSTRACT Objective: To verify the prevalence and perform the clinical characterization of oral clefts in a sample of patients with trisomy of chromosome 18 in Southern Brazil. Methods: This was a retrospective cross-sectional study, performed in a reference clinical genetic service in Southern Brazil. The initial sample consisted of 77 patients diagnosed in the neonatal period with trisomy 18 treated at the Clinical Genetics Service of a referral hospital at Federal University of Health Sciences of Porto Alegre (UFCSPA). The patients’ diagnosis was confirmed by karyotype and care was provided during their stay in the intensive care unit (ICU) of the hospital that is a reference in Southern Brazil for care for malformed patients. The period covered was from 1975 to 2020. Results: During the study period, 77 patients diagnosed with trisomy 18 were treated, most of them in the ICU. Of these, 13 individuals were excluded due to incomplete data. The final sample consisted of 64 patients with an average age of 2.4 years of life, ranging from one day to 16 years old, the majority of whom were female. Regarding face dysmorphisms identified in the sample, three (4,68%) patients had cleft lip and two (3,11%) had cleft lip and palate. Conclusions: This study contributed to the recognition of the characteristics and prevalence of oral clefts in individuals with trisomy 18 in a sample of patients from Southern Brazil. In addition, we described the clinical alterations found in patients with oral clefts, as well as other associated comorbidities, such as cardiac, neurological and pulmonary comorbidities, as well as cranial and facial dysmorphisms.