bluuebunny/crossref_metadata_2025 huggingface dataset:
RAMAI-RAMAI MENOLAK WISATA HALAL: Kontestasi Politik Identitas dalam Perkembangan Wisata Halal di Indonesia
Authors: Makhasi Ghifari Yuristiadhi Masyhari , Rahimmadhi Muhammad Thohir Yudha
Published: May 2020

MasterCard Crescent Rating 2019 data shows Indonesia is the most popular halal tourist destination together with Malaysia. But on the other hand, in 2019 there was a rejection of Halal Tourism in several regions in Indonesia, namely Bali, South Sulawesi, North Sumatra and East Nusa Tenggara. This article tries to analyze why there is a rejection of halal tourism amid the growth of halal tourism in Indonesia. Is it more because of the recent strengthening of the wave of Islamism that has been mounted by practical political interests so that it presents its antithesis namely phobia as a form of cons of hegemony. So that the great potential of halal tourism itself is no longer seen as a great potential that can prosper anyone as a form of the universality of halal tourism. This analytical descriptive research with secondary data uses discourse analysis to answer the problem formulation with the concept of hegemony and identity politics. The conclusion of this article is that the rejection of halal tourism is significantly influenced by identity politics associated with political friction at the national and local level.Data MasterCard Crescent Rating 2019 menunjukkan Indonesia menjadi destinasi wisata halal terpopuler bersama Malaysia. Namun di sisi lain, pada kurun 2019 terjadi penolakan atas Wisata Halal di beberapa wilayah di Indonesia sebut saja Bali, Sulawesi Selatan, Sumatera Utara, dan Nusa Tenggara Timur. Artikel ini mencoba menganalisis mengapa terjadi penolakan wisata halal di tengah pertumbuhan wisata halal di Indonesia. Apakah lebih karena menguatnya gelombang Islamisme akhir-akhir ini yang tertunggangi kepentingan politik praktis sebagai wujud hegemoni sehingga menghadirkan antitesisnya yakni fobia sebagai wujud konter hegemoni, sehingga potensi besar dari wisata halal itu sendiri tidak lagi dilihat sebagai potensi besar yang bisa menyejahterakan siapapun sebagai wujud universalitasitas wisata halal. Penelitian deskriptif analitis dengan data sekunder ini menggunakan analisis wacana untuk menjawab rumusan masalah dengan pisau iris konsep hegemoni dan politik identitas. Hasil penelitian menunjukan bahwa penolakan wisata halal secara signifikan dipengaruhi oleh politik identitas yang terkait dengan friksi politik di level nasional dan lokal.
NARASI INDUSTRI PARIWISATA HALAL DI NEGARA JEPANG DAN JERMAN
Authors: Rahmah Hilda , Tapotubun Hanry Harlen
Published: May 2020

This paper aims to find out how non-Muslim countries such as Japan and Germany develop the halal tourism industry and highlight the narratives of halal tourism in both non-Muslim countries. This study has been done qualitatively in focus on the literature review and discourse analysis method as the main approach. Over time, the halal label has been led to be an inseparable aspect of lifestyle segment in certain society. It did not occur only in the food industry, but also been penetrated into various other industries, one of those is known as halal tourism. According to Global Muslim Tourist Index (GMTI), this phenomenon is not only the Muslim countries Phenomenon, but also increase in the non-Muslim countries. The halal tourism business is expanding and start to be the main economical income by Muslim minority countries, including Japan and Germany. The presence of these two countries in developing halal tourism is unique, because it is not a country with a Muslim majority, but it is precisely the target of foreign Muslim tourists, including Indonesians. Although Indonesia has been named the best halal destination according to GMTI, in fact the interest in halal tourism developed by Japan and Germany is far more promising. No doubt this has become a challenge for Indonesia to enter the this global market competition. Therefore, compared to following the market trend with profit oriented, Indonesia as a Muslim-majority country should deliver halal tourism towards the target of justice and welfare of the people.Tulisan ini bertujuan untuk memahami wacana dan kepentingan yang mengiringi perkembangan wisata halal di Jepang dan Jerman, sebagai negara non-muslim. Hal ini dikarenakan, meskipun berstatus negara non-muslim, keduanya mengalami peningkatan yang cukup signifikan dalam hal pengembangan dan tingkat kedatangan turis muslim. Dengan menggunakan pendekatan teori hegemoni oleh Laclau dan Mouffe yang menekankan pada aspek logic of difference dan chain of equivalent sebagai kunci utama internalisasi wacana hegemonik, tulisan ini dimaksudkan untuk melihat beragam wacana dan kepentingan mengiringi perkembangan wisata halal, baik yang tersirat maupun tersurat. Untuk mancapai tujuan tersebut, metode pengumpulan data akan dilakukan dengan studi kepustakaan yang fokus pada beragam artikel, berita, serta laporan-laporan terkait perkembangan industri pariwisata halal di Jepang dan Jerman. Dari berbagai data dan analisa, tampak jelas bahwa meskipun ada beragam wacana dan kepentingan, perbedaan tersebut berada dalam wacana besar neoliberalisme. Sehingga, wisata halal di negara non-muslim dapat dipahami sebagai sebuah wacana hegemonik yang hanya menguntungkan negara dan pasar tetapi mengesampingkan masyarakat. Dengan belajar dari temuan tersebut, Indonesia sebagai negara dengan populasi muslim terbesar diharapkan mampu mengembangkan industri wisata halal yang ramah, bukan hanya kepada turis dan pemodal, melainkan juga pada masyarakat sebagai garda terdepan industri wisata halal.
PENGARUH KUALITAS PELAYANAN DAN PENGEMASAN DAYA TARIK WISATA TERHADAP KEPUASAN WISATAWAN DI NGEBEL PONOROGO
Authors: A.P Kaukabilla , Kholiq Abdul
Published: May 2020

Ngebel Lake is a superior nature tourism in Ponorogo Regency. The lack of tourist attractions in this district made the local government strongly asked to increase tourism potential in the village of Ngebel. Facilities development and service improvement continue to be carried out in order to attract tourists. This study discusses the quality of service and the packaging of tourist attractions towards the decision of a visit as well as its consideration of tourist satisfaction. The number of samples used was 100 respondents taken from the number of tourists. From the data obtained from observations, documentation, direct interviews and filling out questionnaires. Multiple regression analysis was performed to determine the effect of the independent variables on the dependent variable. The results showed that there were positive and significant differences between the variables of service quality and tourist attraction packaging towards the decision of the visit and its consideration on tourist satisfaction.Telaga Ngebel merupakan tempat wisata alam unggulan di Kabupaten Ponorogo. Minimnya tempat wisata di kabupaten ini, menjadikan pemerintah daerah berupaya untuk meningkatkan potensi wisata di telaga Ngebel. Pengembangan fasilitas dan peningkatan pelayanan dilakukan demi menarik minat wisatawan. Penelitian ini bertujuan untuk mengetahui pengaruh kualitas pelayanan dan pengemasan daya tarik wisata terhadap kepuasan wisatawan. Pendekatan yang digunakan yaitu deksriptif kuantitatif dengan sampel yang digunakan sebanyak 100 responden yang diambil dari populasi wisatawan. Adapun data diperoleh dari observasi, dokumentasi, wawancara langsung dan pengisian kuisioner. Analisis multipel regresi dilakukan untuk menentukan pengaruh independent variable terhadap dependen variable. Hasil penelitian menunjukan bahwa terdapat pengaruh yang positif dan signifikan antara variable kualitas pelayanan dan pengemasan daya tarik wisata terhadap kepuasan wisatawan.
Experimental Evaluation of the Impact of Gadolinium Orthovanadate GdVO4:Eu3+ Nanoparticles on the Carrageenan-Induced Intestinal Inflammation
Authors: Tkachenko Anton S. , Gubina-Vakulyck Galina I. , Klochkov Vladimir K. , Kavok Nataliya S. , Onishchenko Anatolii I. , Gorbach Tatyana V. , Nakonechna Oksana A.
Published: May 2020

Aim: To evaluate the effects of orally administered gadolinium orthovanadate GdVO4:Eu3+ nanoparticles (VNPs) on the course of chronic carrageenan-induced intestinal inflammation. Methods: Samples of small intestinal tissue were collected from four groups of rats (intact, after administration of VNPs, with carrageenaninduced intestinal inflammation, with carrageenan-induced intestinal inflammation orally exposed to VNPs) to assess the intestinal morphology and HSP90α expression. Levels of seromucoid, C-reactive protein, TNF-α, IL-1β and IL-10 were determined in blood serum. Results: Oral exposure to VNPs was associated with neither elevation of inflammation markers in blood serum nor HSP90α overexpression in the small intestine, i.e. no toxic effects of VNPs were observed. Carrageenan-induced intestinal inflammation was accompanied by higher levels of TNF-α and IL-1β, as well as HSP90α upregulation in the intestinal mucosa, compared with controls. Administration of VNPs to rats with enteritis did not lead to statistically significant changes in concentrations of circulating pro-inflammatory cytokines with the trend towards their increase. Conclusion: No adverse effects were observed in rats orally exposed to VNPs at a dose of 20 μg/kg during two weeks. Using the experimental model of carrageenan-induced enteritis, it was demonstrated that VNPs at the dose used in our study did not affect the course of intestinal inflammation.
Association of PAI-1 rs1799889 Polymorphism with Susceptibility to Ischemic Stroke: a Huge Meta-Analysis based on 44 Studies
Authors: Jafari Mohammadali , Jarahzadeh Mohammad Hossein , Dastgheib Seyed Alireza , Seifi-Shalamzari Neda , Raee-Ezzabadi Ali , Sadeghizadeh-Yazdi Jalal , Akbarian Elahe , Neamatzadeh Hossein
Published: May 2020

Background: the PAI-1 rs1799889 polymorphism has been reported to be associated with susceptibility to ischemic stroke. However, the results of previous studies have been inconsistent or controversial. Hence, we performed a systematic review and meta-analysis to evaluate the association of PAI-1 rs1799889 polymorphism with ischemic stroke risk. Methods: A comprehensive literature search was performed on PubMed, Web of Science, Scopus, SciELO, CNKI, and CBD databases up to November 05, 2019. Pooled odds ratio (OR) with 95% confidence interval (CI) were used to access the strength of this association in fixed- or random-effects model. Results: A total of 44 case-control studies with 8,620 cases and 10,260 controls were selected. Pooled data showed a significant association between PAI-1 rs1799889 polymorphism and ischemic stroke risk in the overall populations (GG vs. AA: OR = 0.791, 95% CI 0.633–0.988, p = 0.039; GA vs. AA: OR = 0.807, 95% CI 0.683–0.953, p = 0.012; and GG+GA vs. AA: OR = 0.795, 95% CI 0.637–0.993, p = 0.043). Subgroup analysis by ethnicity revealed a significant association in Asian and Mixed populations, but not in Caucasians. Moreover, stratified analysis by country of origin revealed an increased risk of ischemic stroke in Chinese populations, but not among Dutch (Netherlands) and Swedish. Conclusions: This meta-analysis result suggested that PAI-1 rs1799889 polymorphism was associated with an increased risk of ischemic stroke, especially in Asian and Mixed populations.
Związek wolnego rynku z dyktaturą polityczną: przejściowy czy trwały? Przykład Chin
Authors: Dylus Aniela
Published: May 2020

Aniela Dylus, Związek wolnego rynku z dyktaturą polityczną: przejściowy czy trwały? Przykład Chin [The relation between free market economy and political dictatorship – is it of temporary or permanent nature? The example of China] edited by W. Banach, M.A. Michalski, J. Sójka, „Człowiek i Społeczeństwo” vol. XLVI: Między Chinami a Zachodem. Pytanie o źródła chińskiego sukcesu gospodarczego [Between China and the West. An inquiry into the sources of the Chinese economic miracle], Poznań 2018, pp. 103–119, Adam Mickiewicz University. Faculty of Social Sciences Press. ISSN 0239-3271.The relation between free market economy and democracy has been assumed as a paradigm in the western culture since the Enlightenment. However, this paradigm seems to be violated by markets that flourish under the political dictatorship. Are these markets the exceptions to the rule or maybe their scale does not indicate the necessity of paradigm change? Or maybe we are wrong to assume that capitalism flourish mainly in democratic systems? Is it possible that the relation between communist political dictatorship and liberal economy system is only of temporary nature and people that have economical freedom will demand sooner or later their political freedom? To answer these questions, (1) the paradigm of relationship between free market, its prosperity and democracy and (2) the arguments supporting this relationship have been discussed. Referring to Samuel Huntington’s theory, (3) it has been reminded that many factors, not only economical ones, decide about democratization of political life and some exceptions to this rule have been mentioned. (4) The example of contemporary China is one of the most spectacular example. The short characteristic of (5) its economic condition, (6) its economic system and political dictatorship has been presented and then the attempts have been made to give the arguments either for (7) temporary or (8) permanent relationship between free market and political dictatorship in China. Although the idea of democracy, the rule of law and human rights seems not to be the only alternative base of economical market system, it appears to be prevalent and the only one in a longer period.
The thickness of surface grafting layer on bio-materials directly mediates the immuno-reacitivity of macrophages in vitro
Authors: Xiao JiangWei , Huang Tao , Hu JiJie , Zan Fei , Liao ZhaoHong , Gu RuiCai , Wu Gang , Liao Hua
Published: May 2020

Introducing the surface grafting layers to regulate bio-compatibility and bio-function is an important step in the tissue engineering field. However, whether the thickness variation of the introduced biomimetic layer impacts the behavior of the adhered immune effector cells is yet to be dissected fully. In this study, we used a surface-induced atom transfer radical polymerization (SI-ATRP) method to synthetize and graft poly-phenoxyethyl methacrylate (PHEMA) brushes having different lengths on the glass substrates. Primary murine peritoneal macrophages were collected and cultured on the PHEMA brushes and we investigated the influence of polymer brushes having different lengths on macrophages phenotype and function. Our results demonstrated that the thicker brushes (200 nm and 450 nm) are superior to the thinner layers (50 nm) for macrophages survival, proliferation, cell elongation and migration. Moreover, the thicker brushes are more beneficial for macrophage’s activities and functions, presented by the increased production of M1-associated cytokines IL-6 and MCP-1, the elevated cell phagocytosis and the activation molecule F4/80 expression, and the reduced macrophages apoptosis in thicker brushes-sustained macrophages. Our data suggests that the thickness of the substrate grafting layer directly impacts macrophages recruitment and pro-inflammatory function, which is important in determining the intrinsic immuno-compatibilities of the surface modified-biomaterials and mediates material-host interactions in vivo.
Calcium Phosphate Cement Causes Nucleus Pulposus Cell Degeneration Through the ERK Signaling Pathway
Authors: Zhou Quan , Wu Cenhao , Zha Jiali , Ge Jun , Yan Qi , Wang Yingjie , Song Dawei , Zou Jun
Published: May 2020

While calcium phosphate cement (CPC) is recognized as one of the most likely substitutes for the conventional Polymethylmethacrylate (PMMA), there are very few studies about its intradiscal leakage consequences. Herein, the goal of our study was to examine the effect of CPC particles on the ERK (extracellular regulatory kinase) pathway in human nucleus pulposus cell (HNPC) degeneration. Different concentrations of CPC particles (0.00‰, 0.01‰, 0.05‰, 0.1‰ v/v) were added to human nucleus pulposus cell cultures. After 10 days of treatment, HNPC biological behaviors and degeneration degree were analyzed by CCK-8 assay, crystal violet staining, flow cytometer and western blot. The effect of CPC on the ERK pathway was also analyzed by western blot. After activating the ERK path by overexpressing Ras, HNPCs’ biological behaviors and degeneration degree were analyzed again. We found that CPC particles had a negative effect on human nucleus pulposus cells (HNPCs), which are mainly reflected in cell growth and the cell cycle. After activation of the ERK signaling pathway, the negative effects of CPC on cell growth and the cell cycle were significantly reduced and the degeneration degree of HNPCs was reversed. CPC particles can probably block the activation of the ERK pathway, thus causing the HNPCs’ degeneration.
Q 30: 2‒5 in Near Eastern Context
Authors: Silverstein Adam J.
Published: May 2020

This article aims to contextualize a short Qurʾānic passage – Q 30:2‒5 – with reference to Jewish and Christian materials that have not hitherto been deployed for this purpose. The article builds on the findings of recent scholarship, which reads this passage eschatologically rather than historically, and argues that there are, in fact, two texts that require contextualization: 1) The Qurʾānic verses themselves (which refer only to the fate of “the Romans”); and 2) The early exegetical traditions on these verses (which often add “the Persians” to the eschatological drama). Furthermore, it is argued that the Biblical book of Daniel, and its interpretation in late antiquity, contributed both to the verses themselves and to their exegesis.
The Life and Times of the Ayyūbid Vizier al-Ṣāḥib b. Shukr
Authors: Leiser Gary
Published: May 2020

This is a description and assessment of the career of al-Ṣāḥib b. Shukr (548–622/1153–1225), the most important vizier of Ayyūbid Egypt. Born in the Delta, and raised in an influential family, he studied to become a jurist. After serving as a judge (qāḍī), he entered the administration of Saladin and subsequently became the vizier of two Ayyūbid sultans, al-ʿĀdil and his son al-Kāmil. His ruthlessness in raising money for them by transforming the Egyptian vizierate into a fund raising institution was a critical factor in their ability to stay in power, and in saving Egypt from the Fifth Crusade. At the same time he patronized the religious class and built the first Mālikī law school (madrasa) in Cairo. His vizierate represented a nexus of administrative and religious authority in Egypt.
Differential Rapid Plasticity in Auditory and Visual Responses in the Primarily Multisensory Orbitofrontal Cortex
Authors: Sharma Sudha , Bandyopadhyay Sharba
Published: May 2020

Given the connectivity of orbitofrontal cortex (OFC) with the sensory areas and areas involved in goal execution, it is likely that OFC, along with its function in reward processing, also has a role to play in perception-based multisensory decision-making. To understand mechanisms involved in multisensory decision-making, it is important to first know the encoding of different sensory stimuli in single neurons of the mouse OFC. Ruling out effects of behavioral state, memory, and others, we studied the anesthetized mouse OFC responses to auditory, visual, and audiovisual/multisensory stimuli, multisensory associations and sensory-driven input organization to the OFC. Almost all, OFC single neurons were found to be multisensory in nature, with sublinear to supralinear integration of the component unisensory stimuli. With a novel multisensory oddball stimulus set, we show that the OFC receives both unisensory as well as multisensory inputs, further corroborated by retrograde tracers showing labeling in secondary auditory and visual cortices, which we find to also have similar multisensory integration and responses. With long audiovisual pairing/association, we show rapid plasticity in OFC single neurons, with a strong visual bias, leading to a strong depression of auditory responses and effective enhancement of visual responses. Such rapid multisensory association driven plasticity is absent in the auditory and visual cortices, suggesting its emergence in the OFC. Based on the above results, we propose a hypothetical local circuit model in the OFC that integrates auditory and visual information which participates in computing stimulus value in dynamic multisensory environments.
Success Factors For Small And Medium Industries Based On Creative Industries
Authors: Ardiana Fitria
Published: May 2020

The purpose of this study was to determine the effects of entrepreneurial characteristics, interest in entrepreneurship, business networks, promotion and government support for the success of creative industries based in Magelang Regency. The sampling technique uses non-probability sampling with a convenience sampling approach, as many as 100 entrepreneurs. Data collection techniques using a questionnaire or questionnaire. Data were analyzed using Partial Least Square with reflective measurement models for each latent variable in the study . The suggestion from this research is that entrepreneurs can increase theircourage in taking risks and create interesting and creative things and be more active in participating in programs organized by the government to increase business success and the government can give awards or prizes to entrepreneurs who actively participate in government programs.
Analysis of Poverty and Inequality in Java, Bali, and Lampung
Authors: Setiawan Achma Hendra , Agunggunanto Edy Yusuf , Hayati Banatul
Published: May 2020

According to BPS, the largest distribution of the poor in Indonesia is on the island of Java and the surrounding provinces of Banten, West Java, Central Java, D.I. Yogyakarta, Bali and Lampung, of the total poor population in Indonesia, the Seven Provinces contributed 15.71 million to the poor.

This study aims to analyze Farmer Exchange Rates, Growth of the manufacturing sector, growth of the agricultural sector, Average Length of Education, Percentage of people working in the informal sector on poverty levels, analyze the effect of the ratio of productivity of the industrial sector to the agricultural sector, and the ratio of education to inequality income and analyze the relationship between poverty levels and income inequality in Java, Bali, Lampung. The method used is panel data analysis (pooled data) and correlation analysis as a data processing tool using the Eviews program 9. The results of this study indicate that the influence of the industrial sector is greater than the agricultural sector in reducing poverty, which is -0.47%: -0.40%. Farmer Exchange Rate (NTP) and the ratio of informal education are not significant to poverty, informal education has a positive relationship with poverty, the ratio between the productivity of the manufacturing sector compared with the productivity of the agricultural sector is significant in reducing existing inequality and the ratio of basic education level is not significant to inequality.
Family Hope Program Evaluation in Poverty Alleviation: Benefit Incidence Analysis
Authors: Azhar Luthfi Faishal , Badriah Lilis Siti , Bambang Bambang
Published: May 2020

This research was conducted in the Cigalontang Sub-district, Tasikmalaya Regency, West Java Province. This study aims to analyze: (1) the accuracy of the Family Hope Program in achieving its goals, (2) the characteristics of the Family Hope Program policies in poverty alleviation (pro-poor, progressive, or regressive), (3) the effectiveness of the Family Hope Program implementation. The number of respondents consisted of 195 Beneficiary Families of the Family Hope Program . This study uses primary data, which were collected using interview and questionnaire methods. This study uses analysis methods in the form of Proportion Analysis, Benefit Incidence Analysis, and Appraisal Effectiveness Program. Based on the results of the study, it can be concluded that : (1) The pattern of the Family Hope Program acceptance in the Cigalontang Sub-district is right on target. Because the proportion of the population with income below the poverty line per capita receives the most benefits from the Family Hope Program according to the target, namely, very-poor households. (2) The Family Hope Program in the Cigalontang Sub-district is Pro-Poor, (3) The Family Hope Program in the Cigalontang Sub-district is classified as an effective program.
Adherence to Vitamin D Intake Guidelines in the United States
Authors: Simon Alan E. , Ahrens Katherine A.
Published: May 2020

BACKGROUND:

The American Academy of Pediatrics (AAP) revised its infant vitamin D intake guidelines in 2008. We aimed to examine previously unexplored trends in meeting vitamin D intake guidelines among US infants since 2009 and whether there were differences across demographic subgroups.

METHODS:

We analyzed dietary recall data for infants 0 to 11 months in the 2009–2016 NHANES. We estimated the percentage meeting 2008 AAP vitamin D guidelines, defined as consuming ≥1 L of infant formula and/or receiving a vitamin D supplement of ≥400 IU. We used Poisson regressions to assess trends over time and differences across demographic subgroups.

RESULTS:

Overall, 27.1% (95% confidence interval [CI]: 24.3%–29.8%) of US infants in 2009–2016 met vitamin D intake guidelines, with nonbreastfeeding infants (31.1% [95% CI: 27.6%–34.5%]) more likely to meet guidelines than breastfeeding infants (20.5% [95% CI: 15.4%–25.5%]; P < .01). From 2009–2010 to 2015–2016, overall and for both breastfeeding and nonbreastfeeding infants, there were no significant changes over time in the percentage of infants who met the guidelines (P > .05). Among breastfeeding infants, those with a family income ≥400% of the federal poverty level, with a college graduate head of household, and with private insurance were more likely to meet guidelines.

CONCLUSIONS:

Among US infants, we observed no increase in meeting AAP vitamin D intake guidelines since 2009. Less than 40% of infants met guidelines in nearly all demographic subgroups. These findings suggest renewed consideration of how to best meet vitamin D intake guidelines.
CITOGENÉTICA DEL CÁNCER; ALTERACIONES CROMOSÓMICAS ÚTILES PARA DIAGNÓSTICO OPORTUNO Y PRONÓSTICO EN NEOPLASIAS LINFOPROLIFERATIVAS
Authors: Becerra Medina José Antonio , López Ortiz Juan Bautista
Published: May 2020

Este estudio se basa en la relevancia de la citogenética como una importante herramienta que tiene muchas aplicaciones clínicas en el diagnóstico de enfermedades, como el cáncer. Y el objetivo principal es realizar una revisión crítica de la literatura sobre la citogenética y biología del cáncer, a fin de identificar alteraciones cromosómicas que se relacionan con mayor frecuencia con neoplasias linfoproliferativas, para usarlas como herramienta en el diagnóstico oportuno, pronóstico y monitoreo al tratamiento de pacientes. En la introducción se trata la contextualización y el problema del cáncer, y la descripción de las neoplasias malignas. En los primeros capítulos se analizan las aplicaciones clínicas de estudios citogenéticos de anormalidades malignas y se exponen aquellas neoplasias que se relacionan con alteraciones cromosómicas primarias y secundarias, clasificadas en tres grupos de riesgo. Dichas alteraciones se resumen en una tabla, para beneficio del lector. En los últimos capítulos, se demuestra la importancia del aporte de las alteraciones citogenéticas como uso de biomarcadores útiles para el control de estas enfermedades, apoyándose en las nuevas tecnologías desarrolladas en esta área como son el FISH y la técnica del PCR; y se hacen recomendaciones para avanzar en el uso de la citogenética en esta problemática.
ENCAPSULATION OF BARBERRY FRUIT EXTRACTS BY SPRAY DRYING AND LIPOSOME ENTRAPMENT
Authors: Ardestani S. Berenji , Sahari M. A. , Barzegar M.
Published: May 2020

Barberry is a native Iranian plant including species Berberis integerrima and B. vulgaris. Barberry fruit is used for preparing sauces, jellies, carbonated drinks, candies, food colour powders, jams, marmalades, chocolates, juices, and nectars. They are used as a natural food colorant rich in anthocyanins instead of harmful artificial ones. They contain polyphenols and antioxidants that reduce damage from free radicals and prevent chronic diseases and cancers. Barberry fruit extracts were encapsulated in maltodextrin by spray drying and Liposome Entrapment. The sizes of spray dried particles were reported 1–20 μm by SEM. Dimensions of empty and extract loaded liposomes (B. vulgaris and B. integerrima) were 18–28, 37–51, and 51–77 nm, respectively, by FE-SEM. The moist diameter of liposomes measured by dynamic light scattering (DLS) method at day 0 and after 6 months at –18 °C were as follows; empty liposomes: 163.9±2.23 and 378.90±4.98, liposomes loaded with extracts: 135.2±2.04 and 160.90±2.19 (B. vulgaris) and 113.4±1.83 and 144.20±2.01 nm (B. integerrima). Evaluation of thermal-oxidative decomposition from Differential scanning calorimetry (DSC) results at 0–45–90 days showed that the antioxidant activity and the onset temperature of the encapsulated extract was higher than the control. The extracts encapsulated in liposomes, especially B. integerrima extract, had better antioxidant properties.
IMPROVING THE BREAD QUALITY OF SUNI-BUG DAMAGED WHEAT FLOURS BY SOURDOUGH BREADMAKING AND LIQUID RYE SOUR
Authors: Özülkü G. , Sivri Özay D.
Published: May 2020

The breadmaking quality of bug-damaged wheat flours with high protease activity (HPAWF) and low protease activity (LPAWF) was attempted to be improved by using sourdough (prepared by L. plantarum (SD1) and L. sanfrancissensis (SD2)) and liquid rye sour (LRS) in this study. The effects of sourdoughs (20 and 40%) and LRS (1 and 2%) on the protease activity of the HPAWF were determined by SDS-PAGE. Protease activity of HPAWF decreased with the addition of 40% SD1, 20% SD2, and both levels of LRS (1 and 2%) compared to a control sample. The HPAWF bread samples produced with LRS (1 and 2%) had higher volume (P<0.05) and bread quality as compared to sourdough applications. LPAWF bread sample was comparable with those of 40% SD2 added sample in terms of volume and hardness (N) values (P>0.05), while SD1 addition caused quality losses. The overall results suggested that addition of 2% LRS had promising results for improving bread quality flours that were damaged by suni-bug at low levels.
RELAÇÃO ENTRE O PÚBLICO E O PRIVADO NA EDUCAÇÃO BÁSICA NO BRASIL: projetos em disputa
Authors: Vidal Vera Peroni Maria
Published: May 2020

Este texto tem como objetivo trazer alguns elementos para o debate acerca de como as redefinições no papel do Estado reorganizam as fronteiras entre o público e privado, materializando-se das mais diferentes formas na educação básica pública, enfocando, principalmente quem são os sujeitos individuais e coletivos[1], protagonistas do processo de privatização, tanto do ponto de vista conteúdo das suas propostas e as implicações para o processo de democratização mercadológico, como neoconservador. E ainda, busca trazer elementos sobre qual é o da educação. [1]sujeitos individuais e coletivos na concepção de Thompson, (1981).
NEBExpress Ni Resin Batch Binding Typical Protocol (NEB #S1428) v1
Authors: England Biolabs New
Published: May 2020

NEBExpress® Ni Resin is an affinity matrix for the isolation and purification of polyhistidine-tagged (His-tagged) fusion proteins. It is intended for use in gravity or pressure flow columns, and batch purifications. NEBExpress Ni Resin is comprised of a highly uniform and stable chemical-tolerant resin, pre-charged with nickel ions on the matrix surface. It is resistant to a wide range of chemicals, including NaOH, EDTA, DTT and β-Mercaptoethanol. Purification of ≥10 mg His-tagged protein per 1 ml of resin Intended for use in gravity or pressure flow columns, and batch purifications High specific binding of His-tagged proteins yielding purities of >95% Strong nickel ion binding provides excellent resistance to EDTA and reducing agents. Compatible with commercially available detergent-based cell lysis reagents Isolation and purification of His-tagged fusion proteins under native or denaturing conditions
EVALUACIÓN DE LA ADHESIÓN AL TRATAMIENTO PREVENTIVO DE ENFERMEDADES BUCALES INDUCIDAS POR PLACA BACTERIANA MEDIANTE EL USO DE GOMAS DE MASCAR SIN AZÚCAR: ENSAYO CLÍNICO CONTROLADO
Authors: Martínez Pabón María Cecilia , Mesa Arango Carolina , Martínez Delgado Cecilia María , Pérez Cano Maria Isabel , Isaza Guzmán Diana María , Tobón Arroyave Sergio Iván
Published: May 2020

Introducción: el objetivo consistió en evaluar la adherencia a un tratamiento preventivo de enfermedades bucales inducidas por placa bacteriana, utilizando dos gomas de mascar sin azúcar y establecer su efecto sobre recuentos de bacterias cariogénicas como indicador biológico de los efectos del tratamiento. Métodos: se realizó un estudio de intervención, doble ciego, de grupos paralelos, aleatorizado controlado, en 96 adultos jóvenes universitarios, en un período experimental de 30 días. Los participantes fueron distribuidos en dos grupos con asignación de una goma de mascar con pentitol o con hexitol + complejo CPP-ACP que debían ser consumidas 20 minutos/tres veces al día después de la higiene oral convencional. Al inicio del estudio fueron recolectadas muestras de saliva para evaluar recuentos de Estreptococos del grupo mutans (SM) y Lactobacillus spp. Al finalizar el período experimental, se realizó una encuesta para evaluar los niveles de adherencia al tratamiento y los recuentos bacterianos fueron medidos nuevamente. Resultados: Los recuentos de SM mostraron diferencias estadísticamente significativas entre los grupos de estudio al final del período experimental, con tendencia hacia la disminución en ambos grupos. Se observó diferencia intragrupo en los pacientes que consumieron la goma de mascar con pentitol, con marcada reducción de los recuentos de SM. Conclusión: la estimación final de la adherencia al tratamiento mostró que el tipo de goma de mascar asignada al paciente no tuvo influencia y, por lo tanto, estas pueden ser utilizadas teniendo en cuenta los agentes terapéuticos que más aporten al caso particular del paciente y las preferencias del mismo
El deseo como refugio de la temporalidad: la lectura de Sade en Les mots et le choses de Michel Foucault.
Authors: Yuing Tuillang
Published: May 2020

El siguiente texto busca dar cuenta del lugar que tiene la figura del Marqués de Sade en el trabajo que lleva a cabo Foucault en Les mots et le choses. Se trata de una figura que va a mostrar el límite de la representación y de la conciencia, elementos desbordados por lo inabarcable del deseo y sumergidos en la inmensidad irrepresentable de la historia. Para ello, el texto recoge como antecedente, la función que se le otorga a Sade en Histoire de la folie, como una muestra del retorno de la experiencia trágica de la locura que había sido convertida en objeto de conocimiento por la modernidad. Finalmente, el trabajo presenta algunos elementos que Foucault elabora en torno a Sade como figura de la trasgresión.
Leopold von Sacher-Masoch y Marqués de Sade. Lógicas de la perversión desde de los conceptos “crítica” y “clínica” en el vitalismo de Gilles Deleuze
Authors: Landaeta Patricio
Published: May 2020

En la literatura de Sacer-Masoch y Sade, vida y obra parecen confundirse. Ese sería el precio a pagar por la experimentación conjunta de cuerpo y escritura. Lo cierto es, como intentará plantearse, que la unidad que conforman vida y escritura en las novelas de ambos se desplaza el horizonte de la vivencia personal. A partir de los conceptos de “crítica” y “clínica” se mostrará cómo en cada caso se articula una lógica de la perversión en que se pone en juego un vitalismo literario.
A Natureza em Sade
Authors: Castro Clara
Published: May 2020

a proposta deste artigo é analisar a ideia de natureza na obra clandestina de Sade, mais especificamente, nas histórias de “Justine” (1787/1999) e de “Juliette” (1801). O exame recairá sobre a fala de dois narradores (dos “Infortúnios da virtude” e da “Nova Justine”) e de cinco personagens (Dubois, Noirceuil, Rodin, Braschi e Juliette). Pretende-se estudar quatro noções diferentes de natureza (a compensadora, a criadora, a estúpida e a inexistente) a fim de demonstrar que tais noções formam, na verdade, um único raciocínio, desenvolvido em uma gradação regressiva. Tudo começa em uma natureza onipotente e amoral. Esta se transforma em noção imoral, menos poderosa e que necessita do libertino para desorganizar a matéria, mas passa a se mostrar impotente e inconsequente, até revelar-se uma força tão misteriosa e incompreensível quanto a divindade.
Hegel avec Sade
Authors: Grané Diniz Guilherme
Published: May 2020

o presente trabalho pretende investigar tópicos da leitura que Georges Bataille faz da obra de Sade. Trata-se de uma leitura na qual se busca conjugar temas de Hegel com a literatura sadeana. Mais especificamente, Bataille busca entender uma dinâmica de reconhecimento, conforme lida por Kojève, no modo como Sade propõe para nós o desejo, a partir de sua literatura erótica marcadamente peculiar. Para tanto, após uma breve introdução, veremos como Bataille entende o processo antropogênico, o que desse pensamento pode ser retraçado à leitura kojèviana de Hegel e, enfim, como Bataille observa esses elementos na obra do Marquês de Sade.
UM ESPECTRO RONDA O PARANÁ: O PROJETO SOCIETÁRIO DO PCB E A ELEIÇÃO DE UM DEPUTADO ESTADUAL COMUNISTA, EM 1947
Authors: Costa Regis Clemente da
Published: May 2020

Esse artigo objetiva discutir a eleição de José Rodrigues Vieira Netto como deputado estadual pelo Partido Comunista Brasileiro, no Paraná, em 1947, no contexto da legalidade do partido (1945-1947) e a construção de um projeto societário comunista em vista da transformação social. Apoia-se nas fontes arquivadas pela Delegacia de Ordem Política e Social no Paraná (DOPS-PR) que serviram para fichar, monitorar e processar os militantes comunistas a partir da década de 1930. Esse estudo insere-se no âmbito da História Intelectual e trabalha a partir do conceito gramsciano de intelectual orgânico na tentativa de mostrar as ações do partido no Paraná, privilegiando um olhar sobre o projeto societário comunista no estado e a eleição de Vieira Netto.
A EDUCAÇÃO FRANCISCANA NO COLÉGIO SÃO JOSÉ DOS NATURAIS
Authors: Bordin Reginaldo Aliçandro
Published: May 2020

O objetivo deste estudo é analisar a ação pedagógica franciscana no México realizada no Colégio São José dos Naturais, provavelmente fundado em 1523. Dirigido por Pedro de Gante (1480-1572), tido como um dos mais importantes educadores do México colonial, a escola priorizou a educação de crianças astecas e enfatizou o ensino das letras, das artes e da matemática e também contribuiu para formar artesãos, entre outros ofícios. A educação buscava cumprir o papel de ensinar a doutrina cristã às crianças de diversos grupos sociais: nas capelas, salas de aulas e pátios, os franciscanos organizavam atividades que levavam ao aprendizado dos aspectos principais do catecismo cristão e das mais variadas atividades produtivas. Com essas atividades, os franciscanos acreditavam poder contribuir para erradicar as crenças religiosas nativas ao mesmo tempo em que as crianças seriam preparadas para fazer parte das novas estruturas produtivas e sociais implantadas pelos espanhóis, quando venceram os astecas, em 1521. A importância desse momento particular da história e dos desdobramentos para o México e para o continente Americano justificam estudos dessas primeiras experiências educacionais, das quais Pedro de Gante é o protagonista.
ISTVÁN MÉSZÁROS: POR UMA EDUCAÇÃO PARA ALÉM DO CAPITAL
Authors: Fonseca André Dioney , Serejo Wilson da Silva
Published: May 2020

Este artigo tem como objetivo apresentar a contribuição do filósofo húngaro István Mészáros ao campo da educação a partir, especialmente, da obra Educação para além do capital, publicada em 2005. Pretendemos demonstrar, neste texto de caráter teórico, que, não obstante o fato de Mészáros não ter tomado a educação como tema central em sua vasta produção bibliográfica, há, na fortuna crítica desse autor, uma interpretação não só muito original sobre a educação como também incontornável, diante do grave quadro de crise estrutural do capital no século XXI. Para dar conta dessa proposta, inicialmente, destacamos alguns aspectos da vida e do conjunto da obra de Mészáros que ajudam a entender o percurso intelectual que fundamentou as ideias desse autor sobre a esfera da educação. Por fim, tendo como base o livro Educação para além do capital, procuraremos demonstrar que o pensamento de Mészáros acerca da educação é, atualmente, um ponto de apoio imprescindível para a compreensão dos dilemas educacionais contemporâneos e a superação dos parâmetros dominantes de internalização do padrão de sociabilidade do capital.
L'EDUCAZIONE DELL'UMO IN AGOSTINO D'IPPONA
Authors: Carola Joseph , Nascimento Lorivaldo do
Published: May 2020

RIASSUNTO: Questo studio trattera dell'educazione dell'uomo in Agostino di Ippona. Nella concezione agostiniana educare significa liberare l'uomo dei vizi e realizzare la sua originale apertura all'essere transcendente che é Dio. Tuttavia, l'uomo soltanto può ritornare a Dio se, per primo Dio viene al suo inccontro. Per questo motivo, fin dal momento della creazione, Dio si fa presente nell'uolo, il quale fu creato non soltanto da Dio, ma anche per Dio. Dio educa l'uomo dall'interno attraverso la presenza ontologica ed anche per mezzo della presenza illuminante, dalla quale l'uomo há bisogno per conoscere la vera volontà divina. Ma, per l'uomo non basta solo conoscere. Per essere educato nel cammino del bene l'uomo bisogna anche essere mosso dall'Amore dal proprio Dio. Illuminato nel conoscere e mosso dall'Amore per agire com retitudine, l'uomo viene educato e può lavorare nella costruzione della Cittá di Dio sulla terra. L'educazione dell'uomo in Agostino include le questioni dell'essere, del conoscere, dell'agire. L'educazione per Agostino include le grandi parti della filosofia: metafisica, gnoseologia, ética e politica.
Energy strategy – 2035: legal problems of innovation development and environmental safety
Authors: Zhavoronkova N. G. , Shpakovskii Yu. G.
Published: May 2020

The article analyzes the draft energy strategy of Russia for the period up to 2035, its relationship to other strategic planning documents. The authors focus on the problems of innovative development of the fuel and energy sector for the planned period and the reflection of environmental safety issues in the draft of the new energy strategy.
The influence of the «technological unity of power» on the structure of contractual relations in Russian electric power industry
Authors: Eliseev V. S.
Published: May 2020

The article analyzes the formation of the contractual communication structure in the electric power industry after its reform in the Russian Federation. The electric power industry in the USSR was built on the basis of technological unity. This principle was violated as a result of the privatization of the energy sector. At the organizational level have been produced: a parallel gap of the joint electricity producer; series‑parallel gap of transmission; the functional gap of electricity transmission; electricity market is divided into wholesale and retail. A large number of intermediaries were created. In the future, a special structure of contractual relations was created, which was mandatory. The conclusion of contracts for energy companies became mandatory; contracts became standard; pricing was mandatory. This was done on the basis of the principle of technological unity of the electric power industry, which allowed the author to draw a conclusion about the administrative and legal nature of the structure of contractual relations in the electric power industry.
Features of contractual regulation of relations in the use of renewable energy sources
Authors: Kologermanskaya C. M.
Published: May 2020

The article presents a legal analysis of the features of contractual regulation in the use of renewable energy sources in the Russian Federation and foreign countries. It is noted that in the modern period, the sphere of contractual regulation of relations arising from the use of renewable energy sources remains insufficiently studied, which is why it is necessary to conduct legal research in this area, study the experience of contractual regulation in the field of electricity abroad. For the purposes of developing legal regulation, the author proposes a conditional classification of contracts on various grounds.
La impronta como método no invasivo de toma de muestra para el diagnóstico molecular de la leishmaniosis cutánea en población militar de Colombia
Authors: Méndez Bejarano Claudia Patricia , Pérez Rico Julie Janeth , Rodriguez Angarita Omaira , Velandia Rodríguez Daniel Augusto , Romero Barbosa Yanira Andrea , Alvarado Flechas María Teresa , Valbuena Pinzón Tania Mabel
Published: May 2020

Teniendo en cuenta que los métodos tradicionales de toma de muestra y diagnóstico para la leishmaniosis cutánea presentan limitaciones, como el frotis directo, cuya sensibilidad depende de la pericia del profesional, el aspirado de lesión que puede ser usado para detección de parásitos en lámina, su adn o para cultivos es demorado y exigente, y la biopsia de la lesión que es invasiva y dolorosa se comparó con el método de impronta en papel filtro de la lesión ulcerativa contra el método tradicional de aspirado mediante la técnica de pcr convencional utilizando como blanco una región del adn del kinetoplasto del parásito. En el presente trabajo, la pcr obtuvo una sensibilidad para impronta del 90,07% comparado con el aspirado, el 86,3%, que, además, por ser un método de toma de muestra no invasivo, con pocas exigencias para el transporte, se puede tomar directamente en el área de operaciones a muy bajo costo, resulta ser beneficioso para ser usado en los pacientes con leishmaniosis cutánea del Ejército Nacional de Colombia, que se encuentran en las diferentes áreas de operaciones.
THE ATTRACTIVENESS OF KINESICS IN A SEMIOPRAGMATIC PERSPECTIVE: A STUDY ON LANGUAGE LEARNING
Authors: Wayan Ardi Sumarta I , Wayan Simpen I , Ketut Darma Laksana I , Artawa Ketut
Published: May 2020

Purpose of the study: Language is a productive communication tool for teachers to interact with learners. The use of non-verbal Language in speaking becomes strong support when the speech event takes place. This study aims to determine the elements of kinesics and politeness of the Language of the instructor in learning.

Methodology: The method used in this study uses descriptive methods. The subjects involved in the research were one lecturer in Indonesian language courses andMahasaraswati university students who were taking Indonesian language courses. The study was conducted in 6 different classes for three meetings.

Main Findings: The results showed that non-verbal Language is inherent and contributes to the application of the instructor’s politeness principle in learning. Utilization of kinesics in the politeness of Language perfects a speech that is based on the politeness of Language so that the care of speech harmony can be sustained and to the success in maintaining the face of the speech partner especially emotional closeness between learners and instructors.

Application of this study: Learning includes embedded values ​​and imprinted into a role model for learners. The attitude that is no less important and inherent in the instructor’s self is the kinesic attraction that causes the learner’s pleasure and comfort when learning takes place.

Novelty/Originality of this study: Research in Indonesian has not yet led to politeness in Language. The utilization of non-verbal Language in speaking becomes strong support when the speech event takes place, this is because Language is the main communication tool for interaction in learning.
Embarazo ectópico y abdominal, Hospital de Caldas 1970-1993
Authors: Jaramillo V. Eduardo León , Castro J. Jhon Jairo , Angel G. Rafael
Published: May 2020

Se informa de una paciente con embarazo abdominal de 24 semanas de gestación, atendida en el Hospital de Caldas, Manizales. Se analiza y se compara con otras regiones la incidencia de embarazo abdominal y ectópico y las muertes maternas relacionadas con estas causas, durante el período 1970-1993.