bluuebunny/crossref_metadata_2025 huggingface dataset:
Navidezna prebavljivost surovih beljakovin in surovih maščob pri linijah miši selekcioniranih na višji oziroma nižji odstotek telesnih maščob
Authors: TREBUŠAK Tina , PIRMAN Tatjana , HORVAT Simon
Published: December 2023

Debelost in naraščanje indeksa telesne mase (ITM) predstavljata v današnjem času velik zdravstveni problem pri ljudeh, prekomerna zamaščenost pa je prav tako nezaželena pri reji domačih živali, saj poslabšuje gospodarnost prireje. V naši raziskavi smo preučevali vpliv debelosti laboratorijskih miši na navidezno prebavljivost surovih beljakovin in surovih maščob zaužite krme. V dveh prebavljivostnih poskusih smo uporabili dve selekcijski liniji miši, linijo F (višji odstotek telesnega maščevja) in L (nižji odstotek telesnega maščevja). V prvem poskusu smo uporabili 21 samcev obeh linij (11 linije F in 10 linije L), starih od 9,0 do 18,6 tednov, v drugem pa 23 samcev (11 linije F in 12 linije L), starih od 9,6 do 11,0 tednov. V času poskusa (5 zaporednih dni) smo živali dnevno tehtali, merili količino zaužite krme in zbirali blato. Po postopkih weendske analize smo v vzorcih določili vsebnost surovih beljakovin in surovih maščob v krmi in blatu. Rezultati so pokazali, da med linijama F in L obstajajo statistično značilne razlike v navidezni prebavljivosti surovih beljakovin in surovih maščob. Pri zauživanju krme ni bilo statistično značilnih razlik med linijama, so se pa pokazale statistično značilne razlike pri zaužiti krmi na g telesne mase. Linija L je bolje prebavila tako surove beljakovine (79,6 %), kot tudi surove maščobe (91,8 %), v primerjavi z linijo F, pri kateri je bila navidezna prebavljivost v povprečju 77,1 % oziroma 87,0 % za surove beljakovine in surove maščobe. Glede na dobljene rezultate sklepamo, da z razlikami v navidezni prebavljivosti beljakovin in maščob krme ne moremo razložiti velikih fenotipskih razlik med linijama.
Nekateri pristopi za izkoriščanje heteroze pri navadni pšenici (Triticum aestivum L.)
Authors: TITAN Primož , MEGLIČ Vladimir
Published: December 2023

Heterozo najpogosteje povezujemo s superiornostjo prve filialne generacije nad parentalno. Z gospodarskega stališča pa je še posebej pomembno, da se lahko ta superiornost izraža kot višji produktivni potencial sorte. Zaradi počasne rasti višine povprečnega pridelka zrnja navadne pšenice (Triticum aestivum L.) na svetovni in državni ravni, je uporaba hibridov pri tej gospodarsko pomembni poljščini vedno bolj pomembna. Pogoj za pridelavo hibridnega semena je tujeprašnost, ki jo je pri navadni pšenici možno doseči z indukcijo moške sterilnosti. V preteklosti so bili za indukcijo moške sterilnosti v materni komponenti hibridne sorte predlagani pristopi, kot je uporaba moško sterilne citoplazme (CMS sistem) prenesene iz  Triticum timopheevi Zhuk.. Zaradi svoje kompleksnosti se pristopi na genetski osnovi v praksi niso nikoli dovolj uveljavili. Danes omogočajo sredstva za kemično hibridizacijo razvoj hibridnih sort, ki presegajo pridelek zrnja standardnih linijskih sort tudi za več kot dvajset odstotkov. Alternativo kemični indukciji moške sterilnosti predstavljajo transgeni pristopi. Pridelava hibridnega semena navadne pšenice je tehnološko zahteven postopek o gospodarski upravičenosti katerega odločajo raven heteroze, višina pridelka hibridnega semena na enoto površine in prodajna cena pšenice.
Raznolikost fižola v zbirki Kmetijskega inštituta Slovenije
Authors: ŠUŠTAR-VOZLIČ Jelka , MARAS Marko , MUNDA Alenka , ZADRAŽNIK Tanja , MEGLIČ Vladimir
Published: December 2023

Zbirka fižola, ki jo v okviru Slovenske rastlinske genske banke hranimo na Kmetijskem inštitutu Slovenije, obsega 1035 genskih virov, ki so bili v zadnjih 25ih letih zbrani na območju Slovenije. V zbirki imamo tudi 61 genskih virov, ki smo jih pridobili v okviru sodelovanja v mednarodnih ekspedicijah v tujini ter 39 virov, ki smo jih za potrebe raziskovalnega dela pridobili iz drugih genskih bank v Evropi in svetu. Večina slovenskih virov predstavlja navadni fižol (Phaseolus vulgaris L.), manjši del pa je laškega, turškega fižola (P. coccineus L.). Za vse shranjene vzorce imamo na voljo osnovne podatke. Vsako leto določeno število vzorcev razmnožimo in naredimo osnovno karakterizacijo. Del zbirke smo podrobneje ovrednotili z uporabo morfoloških, biokemijskih in molekulskih markerjev. Rezultati so pokazali, da se je v več stoletjih pridelovanja v Sloveniji oblikovala raznolika dednina, ki jo je vredno ohraniti. Obsežneje smo ovrednotili odpornost na glivo Colletotrichum lindemuthianum, ki povzroča fižolov ožig. Vzorce, shranjene v genski banki, uporabljamo za različne raziskave, med katerimi prevladujejo raziskave sušnega stresa. Prav tako pa jo uporabljamo v žlahtniteljskem procesu za žlahtnjenje novih sort ter za reintrodukcijo starih sort.
Zbirka samoniklih virov rukole v Slovenski rastlinski genski banki
Authors: UGRINOVIĆ Kristina , ŠKOF Mojca
Published: December 2023

Med vrstami, ki jim s skupnim imenom pravimo rukola, v Sloveniji samoniklo rastejo le tri vrste iz rodu dvoredca (Diplotaxis tenuifolia, Diplotaxis muralis in Diplotaxis viminea), medtem ko vrste iz rodu rukvice (Eruca) v naravi niso prisotne. V Genski banki kmetijskih rastlin pri Kmetijskem inštitutu Slovenije je zbranih in shranjenih 19 avtohtonih virov iz različnih predelov Slovenije. Pri vseh smo ocenili nekatere morfološke in agronomske lastnosti. Pri večini virov so prisotni različni tipi rastlin, nekateri viri pa so tudi mešanica različnih vrst. Razmnoževanje v izolaciji se je pokazalo za težavno in ne prav uspešno. Pri različnih virih je bila oploditev v izolaciji različno dobra, iz česar lahko sklepamo, da imajo različno samoinkompatibilnost. V prihodnje bi bilo zbirko potrebno dopolniti z viri iz še nepregledanih predelov Slovenije, vire še podrobneje oceniti in proučiti razmnoževanje v izolaciji.
Prvotne, izgubljene, pretopljene pasme prašičev v Sloveniji
Authors: ŠALEHAR Andrej , ŽAN LOTRIČ Metka , KOVAČ Milena
Published: December 2023

Prvotni prašiči so v literaturnih virih običajno zapisani kot domači, naravni, navadni, kranjski, črni, štajerski oz. dolenjski prašiči in podobno. S pričetkom reje prašičev na Kranjskem se je razvila domača pasma prašičev. Podlaga te pasme so bili deloma domači, največ pa hrvaško-ogrski plemenski prašiči, ki so se postopoma prekrižali s prašiči žlahtnejših pasem, zlasti z veliko belo angleško pasmo. Domača pasma prašičev je bila odporna, imela je visoke noge, raven rilec in močan hrbet. Prašiči so bili skromni in neobčutljivi na mraz. Pri nastanku gorenjskega črnolisastega prašiča so verjetno sodelovale različne pasme: avtohtoni kranjski prašiči, hrvaški prašiči, heševci, angleške pasme (posebej jorkšir) in tudi krškopoljski prašiči. V kakšnem razmerju so sodelovale posamezne pasme, ni mogoče ugotoviti. Gorenjski črnolisasti prašič je bil mesnato-mastnega tipa. Bil je dobro rasten s sorazmerno veliko zmogljivostjo rasti in je imel kakovostno meso. Poudarjena je njegova odpornost in skromnost do pogojev reje. Zahteve trga po mesnatih prašičih so bile vse večje in opuščanje pasme je bilo neizbežno. O pasmah solčavski črni prašič in štajerski črni prašič so znani le skromni zapisi. Pasmi sta bili odporni in skromni ter sta bili izgubljeni.
Child Labour and Health During the Industrialization in Western Europe with Special Reference to Prussia
Authors: Vögele Jörg Peter , Liczbińska Grażyna
Published: December 2023

Child labour is a controversial issue both in present day as well as in past societies. In historical perspective, studies focus on the factory labour of children during the industrialization process. On the one hand, its contribution to the family income is mentioned as a potential positive effect on the living standard of the whole family, on the other hand reference is made to the permanent health risks for children working in the factories. Using qualitative sources, there were contemporary testimonies supporting both views. The present paper, therefore, uses a rather quantitive approach referring to the number of working days lost due to illness, anthropometric indicators such a height and weight, the results of draft examinations as well as mortality differences and cause-of-death rates from “accidents” in urban and rural areas during the nineteenth century. Available data do not provide clear evidence of direct harmful effects of child labour; many indications point to a neutral or even positive effect.
Extraction of the pull force from inertial sensors during the pull test for Parkinson’s disease: A reliability study
Authors: Taniuchi Ryoma , Kanai Shusaku , Hara Amane , Monden Kazuya , Nagatani Hiroaki , Torii Tsuyoshi , Harada Toshihide
Published: December 2023

Objective To examine the inter- and intra-rater reliability of the pull test in patients with Parkinson’s disease (PD) using the extracted pull force.Methods In this inter- and intra-rater reliability study, two raters performed a pull test on 30 patients with PD. The pull force was quantified using inertial sensors attached to the rater’s right hand and the patient’s lower trunk. In this study, the pull force was calculated as an extracted three-dimensional vector quantity, the resultant acceleration, and was expressed in m/s2. Inter- and intra-rater reliabilities were analyzed using the interclass correlation coefficient (ICC) for the pull force and Cohen’s weighted kappa (κw) for the pull test score. Furthermore, Bland–Altman analysis was used to investigate systematic errors.Results The inter- and intra-rater reliability of the pull force was very poor (ICC = 0.033–0.214). Bland–Altman analysis revealed no systematic errors in the pull forces between the two test points. Conversely, κw for the pull test scores ranged from 0.763 to 0.920, indicating substantial to almost perfect agreement.Conclusion The pull test score was reliable despite variations in the quantified pull force for inter- and intra-rater reliability. Our findings suggest that the pull test is a robust tool for evaluating postural instability in patients with PD and that the pull force probably does not affect scoring performance.
Investigation on voltage stability evaluation indicators and algorithms for power systems based on neural network algorithms
Authors: Cai Xi , Quan Chaoyang , Chen Yuanyuan
Published: December 2023

In order to avoid the occurrence of unstable phenomena in the Power Grid (PG), it is necessary to have a thorough understanding of the current operating status of the PG. Research on voltage stability evaluation indicators and algorithms in the power system can assist power system operators in making effective decisions. In this paper, an improved continuous power flow scheme based on Lagrange quadratic interpolation was adopted. Secant method and Lagrange quadratic interpolation method were used for prediction comparison, and Newton method was used to correct the predicted results. This article utilized an online voltage safety assessment and warning model to ensure the safe operation of the PG and reduce the occurrence of faults. To ensure the integrity and accuracy of network dynamic information, a least squares fitting method based on orthogonal functions was adopted to improve the fitting accuracy without increasing communication volume. As the step size increases from 2 to 3, the number of power flow solutions decreased and the solution time increased. The effectiveness of the voltage stability evaluation algorithm in this paper was verified through simulation of two node systems: New England 39 and IEEE118.
Generalized Anti-Symmetry Laws in Groupoids
Authors: Ahn Sun Shin , Kim Hee Sik , Seo Young Joo
Published: December 2023

In this paper, we introduce the notion of generalized anti-symmetry laws in groupoids, and we apply this concept to several algebraic structures. Moreover, we show that every Fibonacci sequence on (C, *) is periodic.
A Critical p(x)-Laplacian Steklov Type Problem with Weights
Authors: Allaoui Mostafa , Darhouche Omar
Published: December 2023

This paper is concerned with the existence of nontrivial weak solutions for a class of p(x)-Laplacian problem under Steklov boundary condition. The variable exponent theory of generalized Lebesgue-Sobolev spaces and the concentration-compactness principle for weighted variable exponent spaces are used for this purpose.
Paracompactness and Open Relations
Authors: Gutev Valentin
Published: December 2023

The countably paracompact normal spaces were characterised by Dowker and Katětov in terms of an insertion property. Dowker also described them by normality of their product with the closed unit interval. Michael used the Dowker-Katětov insertion property to motivate his selection characterisation of these spaces. Morita extended in a natural way Dowker’s product characterisation to all τ-paracompact normal spaces. In this paper, we look at these results from the point of view of open relations. Insertions and selections are equivalent for such relations. Furthermore, we obtain a natural characterisation of τ-paracompact normal spaces in terms of selections for convex-valued open relations. Based on this, we give simple alternative proofs of the above mentioned results. Other applications are obtained as well.
Turizmusra alapozott területfejlesztési modell kialakítása a határmenti térségekre vonatkozóan
Authors: Nagy Dávid , Horeczki Réka , Lados Gábor
Published: December 2023

A tanulmány alapvetően elméleti, összegző megközelítést alkalmaz. Elsősorban az eddig megismert kutatások eredményeinek figyelembevételével kívánja egy új területfejlesztési modell elméleti kereteit meghatározni. Az elméleti alapvetések közül meghatározó jelentősége van a határmenti térségek lehatárolásának, a határon átnyúló együttműködés értékelésének. A kereskedelem és a vendéglátás, illetve a helyi termék és helyi élelmiszer fogalmának tisztázása is hozzájárul a tárgyilagos értelmezéshez.

A tanulmány célja egyes gazdaságilag és társadalmilag hátrányosabb pozíciójú határmenti térségek felzárkózási lehetőségeinek felmérése, ezen területek problémáinak azonosítása, az egyes hátrányok leküzdésének elméleti megalapozása. A kutatásban megvizsgáljuk, hogy mik lehetnek egy a kulturális örökségen alapuló területfejlesztési modell alkalmazásának feltételei, milyen adottságokkal kell rendelkeznie az adott térségnek. A tanulmányban bemutatásra kerülő modell segítségével olyan turisztikai fejlesztéseket és a hozzájuk kapcsolódó fejlesztési eszközöket lehetséges kidolgozni, amelyek jelentős terültfejlesztési hatást tudnak elérni a környezetükben.
Entre changement et organisation : le travail de consultant, source clinique et ressources réflexives psychosociologiques pour un plus grand pouvoir d’agir
Authors: Rousseau Martial , Lorrain Marie-Josée
Published: December 2023

Cet article prend pour objet de recherche l’enjeu de développement de compétences de réflexivité chez les consultant.es en développement organisationnel, parties prenantes de la gestion du changement organisationnel (CO). La littérature scientifique le relève bien, les défis occasionnés par le CO sont difficiles à surmonter pour les gestionnaires, comme pour leurs expert.es. Paradoxalement, ces derniers ont du mal aussi à les relever pour leurs propres CO. L’article présente ainsi une réflexion appuyée sur des exemples de terrain dans une visée de promotion d’une pratique réflexive basée sur l’interdisciplinarité psychosociologique comme forme d’expérimentation d’un plus grand pouvoir d’agir sur le CO. Une fois démontrée la nécessité d’une perspective au plus proche du réel du travail pour mieux appréhender le vécu du CO, une relecture est faite à l’aide d’une partie des résultats de trois recherches-actions en milieu de consultation organisationnelle, des effets sur la santé au travail de consultant.es, de la cooccurrence entre les CO du travail – notamment ceux reliés à la pandémie de COVID-19 – et l’exigence de la révision de leurs pratiques professionnelles. L’interdisciplinarité psychosociologique mobilisée dans ces recherches a alors amené les participant.es à approfondir leur compréhension des effets du CO sur l’exercice de leur métier de consultant.e. Ces recherches-actions leur ont également permis d’élargir et diversifier leur répertoire de stratégies d’amélioration de la qualité de leur travail par le dégagement de marges de manoeuvre et d’accroissement de leur pouvoir d’agir. Ainsi sont examinées les conditions de réussite du CO, amenant les auteurs à proposer un modèle intégré du pouvoir d’agir pour un tel objectif.
Sex-Specific Acute Cerebrovascular Responses to Photothrombotic Stroke in Mice
Authors: Raman-Nair Joanna , Cron Gregory , MacLeod Kathleen , Lacoste Baptiste
Published: December 2023

Mechanisms underlying cerebrovascular stroke outcomes are poorly understood, and the effects of biological sex on cerebrovascular regulation post-stroke have yet to be fully comprehended. Here, we explore the overlapping roles of gonadal sex hormones and rho-kinase (ROCK), two important modulators of cerebrovascular tone, on the acute cerebrovascular response to photothrombotic (PT) focal ischemia in mice. Male mice were gonadectomized and female mice were ovariectomized to remove gonadal hormones, whereas control (“intact”) animals received a sham surgery prior to stroke induction. Intact wild-type (WT) males showed a delayed drop in cerebral blood flow (CBF) compared with intact WT females, whereby maximal CBF drop was observed 48 h following stroke. Gonadectomy in males did not alter this response. However, ovariectomy in WT females produced a “male-like” phenotype. IntactRock2+/−males also showed the same phenotypic response, which was not altered by gonadectomy. Alternatively, intactRock2+/−females showed a significant difference in CBF values compared with intact WT females, displaying higher CBF values immediately post-stroke and showing a maximal CBF drop 48 h post-stroke. This pattern was not altered by ovariectomy. Altogether, these data illustrate sex differences in acute CBF responses to PT stroke, which seem to involve gonadal female sex hormones and ROCK2. Overall, this study provides a framework for exploring sex differences in acute CBF responses to focal ischemic stroke in mice.
Rowan Hillson Inpatient Safety Award 2023: a new online patient flagging system for effective and safe diabetes patients’ follow-up when discharged from hospital
Authors: Soo Shiu-Ching , Garchitorena Jocelyn , Ramos Vilma , Lim Chung Thong
Published: December 2023

One of the biggest challenges in improving patient safety is identifying them promptly when discharging them from hospital to allow effective planning of follow-ups. Previously, our diabetes team had to undergo a manually laborious pathway to achieve this, thereby risking delays and patient safety, and making poor use of time. When our hospital adopted the new software NerveCentre, we took this as an opportunity to make changes within the system to improve this aspect of diabetes care. NerveCentre initially had minimal diabetes care features. By working closely and meticulously with the company and hospital IT department, we developed a new diabetes ‘dashboard’ in the software that allows all diabetes inpatients to be flagged up effectively to the diabetes team, both upon admission and upon discharge. The dashboard could also hold all the important diabetes information relevant to the patient. This initiative was made possible with a great team understanding of the available resources and which aspects of inpatient diabetes care needed to be improved. We now have a safer and more efficient pathway for following up on diabetes patients upon discharge. This is also evident in our 3-month data: they show a 100% follow-up rate, timely telephone follow-up when required, and that fewer outpatient face-to-face clinic appointments are needed. We received positive feedback from healthcare members and patients. In addition, our initiatives are also easily translatable to other electronic software or adaptable by other hospitals. We are grateful to be winners of the prestigious Rowan Hillson Inpatient Safety Award 2023, and we hope that this will serve as a platform to allow greater exposure of this project idea to other healthcare professionals.
Editorial
Authors: Ramirez Hermida Camilo Ernesto
Published: December 2023

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San Juan Unified School District Newcomer Support: Promising Practices
Authors: Lavadenz Magaly , Kaminski Linda , Armas Elvira
Published: December 2023

This report was developed through a partnership between the Policy Analysis for California Education (PACE) Newcomer Research-Practice-Policy Partnership and the Center for Equity for English Learners (CEEL) at Loyola Marymount University (LMU). It presents a case study that identifies promising practices for newcomer education implemented in San Juan Unified School District (SJUSD), one of 12 local educational agencies (LEAs) funded under the California Newcomer Education and Well-Being (CalNEW) project between 2018 and 2021. The case study was conducted during a 2022 summer program for recently arrived immigrant students. Using interviews with 32 school and community leaders and educators, a review of 65 program documents, and observations of 15 classrooms using a tool focused on effective instructional practices for newcomer education, four overarching themes that illustrate promising practices are identified a) building on community cultural wealth, b) leveraging multiple and differentiated resources, c) developing educator capabilities to teach and support newcomer students, and d) designing newcomer program and placement practices. Findings also reveal three overarching challenge areas faced in program implementation including a) grappling with conflicted ideologies, b) ongoing curricular needs and instructional supports for newcomer students, and c) building a comprehensive ELD program design. Based upon the findings for promising practices and challenges, the authors propose three implications for building effective systems to support newcomer students a) sustain newcomer program commitments, b) uphold assets-based narratives about immigrant /refugee students and communities, and c) strengthen local, state, and national newcomer education policy coherence.
Unschooling vs. Classic Methods and Forms of Homeschooling from the Perspective of the Parents of Homeschooled Children
Authors: Rochovská Ivana , Dolinská Eva , Porubčanová Dáša , Gažiová Mária
Published: December 2023

The research is concerned with the possibilities of unschooling in Slovakia, the Czech Republic and Poland. It applies both quantitative and qualitative approaches. Using an open-ended questionnaire, it maps the opinions of 78 parents from Slovakia, the Czech Republic and Poland on the influence of the preferred methods and forms of homeschooling (unschooling, classical methods and forms) on the course and problems of the compulsory testing of a child in an umbrella school. Based on the research findings, it can be stated that the parents of homeschooled children perceive unschooling mainly as self-arranged education, the support of the child’s interests, and also complement it with other methods and forms of education. The problems during compulsory testing in an umbrella school, which were presented by the respondents, consisted firstly of subjectively negative evaluations of the course of the testing, statements concerning the respondents’ fear and descriptions of specific situations or the behaviour of the examiner. The research has also shown that the choice of the methods and forms of homeschooling does not affect whether the parents and children face more problems during the compulsory testing.
Innovative methods for air micropollution research
Authors:   University of Latvia, Faculty of Geography and Earth Sciences, Djubina Nikola , Jansone Kristiana , Sozinova Olga
Published: December 2023

Microscopic biological pollution, such as pollen, can have detrimental effects on human health, serving as a primary cause of respiratory allergies and pollinosis. Furthermore, pollen, as a prominent constituent of biological microscopic pollution, may contribute to the dispersion of industrial pollutants due to the accumulation of chemical elements on its surface. This study aims to evaluate the capacity of pollen to adhere to and transport particulate matter, including potential microplastics. The study encompasses a comprehensive approach, involving multiple aspects of pollen collection. Firstly, pollen samples were obtained directly from plants. Additionally, pollen was collected from various surfaces, representing different environmental contexts. Furthermore, specialized techniques were employed to capture pollen from airflow. Lastly, controlled laboratory conditions were established to simulate pollution of pollen samples. The collected pollen samples were then subjected to analysis using a scanning electron microscope to examine the composition of the pollen wall, detect different chemical elements, and identify the presence of nanometer-sized particles on the pollen surface. Through this investigation, two distinct types of pollen samples were differentiated: clean and polluted. The analysis of clean pollen samples revealed the presence of chemical elements, including oxygen (O), carbon (C), potassium (K), phosphorus (P), and calcium (Ca), on the surfaces of hazel (Corylus) and alder (Alnus) pollen. It should be noted that the concentration of these elements may vary depending on factors such as plant species and growth conditions. Moreover, hazel pollen (Corylus) exhibited the presence of chemical elements like lead (Pb), zinc (Zn), and tin (Sn), which can be attributed to environmental pollution. This abstract presents a preliminary overview of the study, with future research planned to expand upon these initial findings. Subsequent investigations will involve the inclusion of additional plant species and rigorous laboratory experiments to further elucidate the variations in pollen wall composition across different plants, while also considering the influence of diverse growth conditions and environmental factors.
Selection of Non-vitamin K Antagonist Oral Anticoagulant for Stroke Prevention in Atrial Fibrillation Based on Patient Profile: Perspectives from Vietnamese Experts. Part 1
Authors: Ho Tri Huynh Quang , Ton Minh That , Nguyen Viet Lan , Pham Hung Manh , Hoang Sy Van , Vo Nhan Thanh , Nguyen Thai Quoc , Pham Linh Tran , Mai Ton Duy , Nguyen Thang Huy
Published: December 2023

In Asia, especially Vietnam, AF is a common arrhythmia and is linked to a higher risk of stroke and systemic embolism. Anticoagulation therapy for stroke prevention in AF patients can result in bleeding complications. To effectively manage AF, adopting appropriate anticoagulation and addressing modifiable risk factors are crucial. Vietnamese clinicians are particularly interested in non-vitamin K antagonist oral anticoagulants (NOACs), a recent development in AF treatment. However, the lack of head-to-head trials comparing NOACs makes selecting a specific NOAC challenging. This review aims to provide a comprehensive overview of the available clinical evidence on NOACs for stroke prevention in AF to assist clinicians in making informed decisions and improving treatment outcomes in patients with AF. The first part of this review will present the current landscape of AF in Vietnam, focusing on AF prevalence and highlighting gaps in clinical practice. Furthermore, this part extensively discusses the anticoagulation strategy for both primary and secondary stroke prevention in AF.
Az antivirális terápia szerepe a B-sejtes non-Hodgkin lymphoma kezelésében krónikus hepatitis C vírus fertőzés esetén
Authors: Csiszár Orsolya , Rejtő László , Varju Lóránt , Krenács László , Bagdi Enikő , Szerafin László
Published: December 2023

Bevezetés

A marginális zóna lymphomás betegekben a hepatitis C vírus pozitivitás viszonylag gyakori (39%). Krónikus hepatitis C vírus fertőzésben a non-Hodgkin lymphoma incidenciája 15%, ami magasabb, mint az átlagpopulációban (1,5%). Marginális zóna lymphomában az antivirális kezelés komplett remissziót eredményezhet.

Betegek és módszer

Két marginális zóna lymphomában szenvedő, hepatitis C vírussal fertőzött beteg esetét mutatjuk be.

Eredmények

Két hepatitis C vírus fertőzött marginális zóna lymphomás betegünk antivirális kezelés hatására komplett remisszióba került, amely az egyik betegnél két éve tartósan fennáll. A másik betegnél az eredményes kezelést követően négy év után jelentkező inguinális lymphadenomegalia hátterében szekunder aktivált B-sejtes diffúz nagy B-sejtes lymphoma igazolódott, amely immunkemoterápia hatására komplett remisszióba került.

Megbeszélés

Non-Hodgkin lymphoma diagnózisakor minden esetben ajánlott a hepatitis C vírus szerológia elvégzése. A hepatitis C vírus pozitivitás mellett kialakult marginális zóna lymphoma kezelése immunkemoterápia nélkül, antivirális kezelés hatására is eredményes lehet.
Assessment of influence of silane modified zirconia nanoparticle content on weather resistance of water-borne acrylic coating
Authors: Nguyen Thuy Chinh  , Dao Phi Hung  , Nguyen Xuan Thai  , Nguyen Anh Hiep  , Thai Hoang
Published: December 2023

Water-borne acrylic resin has attracted much attention thanks to its environmetally  friendly, high weather stability, good mechanical properties, high toughness. It is widely used in coatings, ships, bridges, locomotives, etc. In this work, the effect of ZrO2 nanoparticles content which were modified with (3-glycidyloxypropyl)triethoxysilane (GPTS) on the weather resistance of the acrylic emulsion coatings was tested and discussed. The change in functional groups, carbonyl index value, gloss, weight and morphology of the coatings before and after accelerated weathering test was investigated. The obtained results showed that the GPTS modified ZrO2 nanoparticle content had a significant effect on the characteristics of acrylic emulsion coatings. The 2 wt.% content of GPTS modified ZrO2 nanoparticles exhibited a highest efficiency in improvement of weather resistance of acrylic emulsion coatings. This result indicated that acrylic emulsion coating filled by the GPTS modified ZrO2 nanoparticles is potential for outdoor applications.
Application of face centered composite central for optimization of pangasius catfish aquaculture wastewater treatment using potassium ferrate
Authors: Phuc Hoang Gia , Ngan Dinh Kim , Quan Dang Ngoc , Khoa Tran Le Dang , Khoi Tran Tien , Huy Nguyen Nhat , Hung Hoang Phi , Chau Nguyen Huynh Bao , Thuy Nguyen Thi
Published: December 2023

This study applied ferrate in aquaculture wastewater treatment as a multi-purpose agent for pollutants’ oxidation, coagulation, and disinfection. Pangasius catfish aquaculture wastewater samples were collected from three sources and their characteristics were analyzed. Face Centered Composite Central (FCCC) design was utilized for designing the experiments with two independent factors (i.e., pH and ferrate dose) and 6 responses (i.e., effluent concentrations of COD, turbidity, PO43-, TKN, NH4+, and log reduction of coliform). The effects of the two factors on the responses were evaluated and the optimum conditions for each response and also for all responses were discussed. The results showed that the wastewater with low frequencies of water renewing required treatment before discharging or recirculating. pH, ferrate dose, and their interaction affected differently on the responses. The treatment was preferred at the acidic conditions for COD, turbidity, and TKN removals, but the basic environments for coliform, NH4+, and phosphate removals. However, the effect of pH on the treatment depended on the ferrate dose. The optimum working condition for all responses was suggested at pH 3 and 20 mg/L of ferrate dose by which the treatment efficiencies reached 99.985 % (log reduction of 3.826), 96.8 %, 93.0 %, 85.7 %, 61.7 %, and 50.0 %, for coliform, PO43-, turbidity, COD, NH4+, and TKN, respectively. These pollutants’ effluent concentrations met well the allowable values for discharging while the pH value required adjustment post - treatment. A further study focusing on pH and NH4+ treatment is suggested for the recirculation purpose of the treated water.
A certain method of construction of Thiele-Hermite continued fraction at a point
Authors: Pahirya Mykhailo , Myslo Yuliia
Published: December 2023

The problem of interpolation of the function of a complex variable at a point of a compact set by the Thiele-Hermite continued fraction is investigated. Formulas for calculating the coefficients of the continued fraction based on values of the function and its derivates at a point are obtained. Several examples of computations are provided.
Percepção de riscos e benefícios em medicamentos e procedimentos médicos: O que pensam homens e mulheres?
Authors: Vieira Kelmara Mendes , Flores Silvia Amélia Mendonça , Mendes-Da-Silva Wesley
Published: December 2023

Resumo Objetivo: Os homens estão mais inclinados a assumir riscos do que as mulheres? A resposta a essa pergunta é de relevância imediata para várias questões econômicas, incluindo o comportamento humano em relação ao consumo de medicamentos e procedimentos médicos. Este trabalho tem como objetivo identificar os benefícios percebidos do consumo de medicamentos, centrado na avaliação do risco farmacêutico. Originalidade/valor: A literatura documenta que riscos e benefícios podem ser considerados os principais trade-offs na tomada de decisão do consumidor, inclusive na indústria farmacêutica. É um tema atual com alto potencial de impacto social por causa dos muitos casos identificados de Covid-19. Nos países em desenvolvimento, a maioria dos medicamentos é utilizada por indivíduos que se automedicam, pois o acesso aos cuidados de saúde pode ser insuficiente. A automedicação é um problema potencialmente maior, pois nesse caso o uso de medicamentos geralmente segue o conselho de amigos, parentes e vizinhos. No entanto, há pouca evidência empírica sobre esse problema no contexto dos países emergentes. Design/metodologia/abordagem: Trata-se de uma pesquisa com mais de mil indivíduos em que se utilizou um modelo de regressão estendido (MRE) em um dos maiores países do mundo, o Brasil. Resultados: De acordo com os resultados obtidos, as mulheres percebem mais riscos e benefícios do uso de medicamentos e procedimentos médicos. A percepção dos benefícios dos medicamentos pode ser explicada pelas seguintes dimensões: risco (danos pessoais, alerta de risco e conhecimento do risco), gênero, uso regular e benefícios dos procedimentos médicos. Em relação às dimensões de risco, quanto menor a percepção de danos pessoais e quanto maior a percepção de alerta e conhecimento de risco, maiores os benefícios percebidos do uso de medicamentos.
A systematic and meta-analytical review of soybean mechanized harvesting in South America
Authors: Carreira Vinicius dos S. , Aleixo Edward V. , Ribeiro Nágilla M. , Santos Jamile do N. , Silva Rouverson P. da
Published: December 2023

ABSTRACT Grain losses pose a threat to agricultural sustainability, particularly in developing countries. Mechanized harvesting is a key process in which losses occur; thus, its investigation is essential. Therefore, a systematic and meta-analytical review was conducted to encompass studies on quantitative soybean losses during harvesting in South America from the last two decades. The initial search yielded 1,094 scientific articles; however, only 25 studies met the inclusion criteria. This study provides an overview of technical aspects monitored on farms, guidelines to ensure efficient harvesting and literature gaps for further innovations. Because studies on soybean losses were predominantly based on continuous observational data and lacked methodological quality according to a quality scoring, only four studies were included in the meta-analysis. The meta-analysis results showed a significant relation between losses and the combine age, indicating that combines with over 10 years of use result in higher losses than newer ones (p ≤ 0.05). Conversely, operating at speeds exceeding 5 km h-1 did not lead to significant increases in soybean losses (p > 0.05). Many decisions can be taken at the farm-level to reduce losses, such as proper training of workers and adequation of combine harvesters according to each crop condition. The insights described here are timely for paving the way towards innovation in harvesting systems and minimizing grain losses by understanding the critical points within the context improving yields during soybean harvesting.
Secondary metabolites of Java cardamom leaves extract function under shading and nitrogen doses
Authors: Arista Rini A. , Nurcholis Waras
Published: December 2023

ABSTRACT Java cardamom is a species of herbal medicinal plant endemic to West Java, Indonesia, that has been used for a long time in traditional medicine. The effects of shading and nitrogen doses on the Gas Chromatography-Mass Spectrometry (GC-MS) profile, total phenolic and flavonoid contents, and antioxidant activity in the ethanol extract of Java cardamom leaves were investigated in this study. The experiment was conducted using a split-plot scheme with three replicates. The main plot constituted shading (without, 25, 50, and 75%), and the sub-plot comprised nitrogen doses (control, 0.9, and 1.36 g nitrogen fertilizer per polybag). GC-MS analysis found 27 compounds in the ethanol extract of Java cardamom leaves. The compounds 1.8-Cineole (36.87%) and 5-Hydroxy-3,7,4’-trimethoxyflavone (18.83%) had the highest concentrations in the combination of 25% shade with 0.9 g N fertilizer per polybag and 50% shade with 1.36 g N fertilizer per polybag. The highest total phenolic content (1.26 mg gallic acid equivalent g-1 dry weight), flavonoid content (3.42 mg quercetin equivalent g-1 dry weight), and ferric reducing antioxidant power (FRAP) antioxidant activity (5.80 μmol Trolox equivalent antioxidant capacity g-1 dry weight) were found with 75% shade. Metabolites 1-Methyl-4-isopropyl-cis-3-hydroxycyclohex-1-ene-6-one, 4-propoxy-catechol, cyclohexane, tert-pentyl-, cis-p-Menth-2,8-dienol, cis-carveol, and cis-p-mentha-1(7),8-dien-2-ol were responsible for antioxidant activity in the ethanol extract of Java cardamom leaves. Shade of 75% is recommended to produce optimal antioxidant activity and phenolic and flavonoid content from Java cardamom leaf extract.
TRANSLATION AND CROSS-CULTURAL ADAPTATION OF THE KNOWLEDGE TRANSLATION PLANNING TEMPLATE FOR THE BRAZILIAN CONTEXT
Authors: Schmidt Catiele Raquel , Barwick Melanie , Lorenzini Elisiane
Published: December 2023

ABSTRACT Objective: to translate, cross-culturally adapt, and validate the content of the Knowledge Translation Planning Template, a research dissemination planning tool, into Brazilian Portuguese. Method: this is a methodological study, sequentially divided into six stages: initial translation, translation synthesis, back-translation, judges' committee, pre-test, and approval of the adapted version by the instrument author. The judge's committee assessed content validity using the modified Kappa and Content Validity Index. The test was conducted with teachers and students from a Federal University of Santa Catarina graduate program. Results: the process of translating and back-translating the tool showed no discrepancies in terms of meaning. The committee was composed of seven judges who carried out semantic, cultural, and conceptual evaluations and made notes on the translation of the content. At this stage, the content validity showed excellent values for the Content Validity Index and modified Kappa, with 0.99 and 0.816, respectively. The tool was tested with 30 teachers and postgraduate students, where 90% of the respondents considered the tool to be sufficiently comprehensive and that all the items were relevant to the purpose of the instrument. In the last stage, the documents were analyzed together with the author of the original tool and the final version was approved. Conclusion: the Modelo de Planejamento de Tradução do Conhecimento results from a careful translation process, cross-cultural adaptation, and tool content validation. This has resulted in a tool that is applicable and understood by the target audience, which shows consistency in the equivalence of translation and cross-cultural adaptation for Brazil.
The challenges of education in contexts of increasing migratory diversity: (mis)adjustments, adaptative practices and creativity in Portuguese schools
Authors: Sacramento Octávio , Challinor Elizabeth , Silva Pedro G.
Published: December 2023

Abstract We discuss the repercussions of the intensification and heterogeneity of contemporary migrations, especially forced migrations, in compulsory schooling contexts in Portugal. Our objectives are (i) to identify the major educational challenges arising from transnational migration, (ii) to understand how schools, still very much rooted in an educational-pedagogical nationalism, adjust to these challenges and (iii) to understand the practices of educational agents in complex circumstances and subjected to many constraints. We draw on data from qualitative fieldwork that we have been carrying out for seven years on the settlement and integration of migrants in the North and Centre of Portugal. From the analysis of this data, we found that schools have been gradually adapting to the multiple challenges (support, resources, skills and specialised pedagogies) raised by migration. The discretionary capacity, informality, creativity and goodwill of educational agents have been fundamental to this, often compensating for the lack of guidelines and resources.
Imigração venezuelana, fronteira e interculturalidade: uma análise das experiências de educadoras e educadores em escolas públicas de Boa Vista (Roraima)
Authors: Generali Sabrina , Cogo Denise
Published: December 2023

Resumo Este artigo tem como objetivo analisar as experiências de educadores(as) da rede municipal de ensino da cidade de Boa Vista (RR) relacionadas à presença da diversidade imigratória de crianças venezuelanas e às possibilidades de inclusão de práticas interculturais em espaços escolares. O marco teórico abarca os conceitos de fronteira, interculturalidade e imigração. A metodologia, de caráter qualitativo, abrangeu entrevistas e pesquisa exploratória, bibliográfica e documental. A análise empírica se desenvolve em torno de três dimensões das experiências de educadores(as) relacionadas à interculturalidade: a visão dos(as) educadores(as) sobre a relação com a fronteira, as escolas de Boa Vista como espaços de diversidade migratória e a ausência de políticas públicas voltadas à interculturalidade. Como resultados, observamos possibilidades e limites de desenvolvimento de práticas educativas interculturais no contexto da fronteira, a ausência de projetos e políticas interculturais nas escolas e o entendimento de que a presença de migrantes é provisória.
Educação superior e reconhecimento de diplomas: ações de extensão desde uma universidade pública e de fronteira no Brasil
Authors: Fernández Paula Daniela , Wimer Fernando Romero
Published: December 2023

Resumo Uma questão central para o exercício profissional no exterior é o reconhecimento de diplomas de ensino superior, procedimento cheio de empecilhos, que afeta pessoas formadas em diferentes países. Diante disso, criamos uma ação de extensão (2019-atual) para orientar sobre o tema: O Núcleo de orientação sobre revalidação e reconhecimento de diplomas de ensino médio e ensino superior, projeto desenvolvido em uma universidade brasileira. Com base nisso, pretende-se abordar o procedimento de reconhecimento de diplomas de ensino superior na Argentina, no Brasil e no Paraguai, e relatar e analisar as experiências do Núcleo. Para atingir esse objetivo, trabalhamos com técnicas de pesquisa qualitativa que permitiram observar que há uma grande demanda para o reconhecimento de diplomas no Brasil. Como conclusões, destacamos a relevância de contar com um corpo de profissionais capacitado sobre o procedimento, bem como a necessidade de estabelecer políticas que simplifiquem o processo.
Reflexiones a la luz de los derechos humanos: análisis respecto a la movilidad humana y diversidad conforme jurisprudencia constitucional ecuatoriana
Authors: Cabrera Andrea Carolina Subía
Published: December 2023

Resumen El objetivo del trabajo fue identificar, a la luz de los derechos humanos, los indicadores estructurales y de proceso emitidos en la jurisprudencia constitucional ecuatoriana respecto a la movilidad humana y diversidad, con especial énfasis en la perspectiva interseccional. Con fundamento en una metodología con enfoque cualitativo, investigación análisis jurisprudencial, método analítico y técnica revisión documental, se encontró que las políticas de control migratorio e integración social resultan insuficientes, se requieren adoptar los estándares de protección internacional de personas en situación de movilidad humana hacia la prevención de su discriminación y desigualdad múltiple.
Implementation of Participatory Research in Vulnerable Context: Methodological Strategies and Challenges
Authors: Seibel Bruna Larissa , Serafim Raysa Schmitz , Silva Nathassia Santos da , Araújo José Antônio Caetano , Springer Paul Russell , Hollist Cody Stonewall
Published: December 2023

Abstract Participatory methods contribute to scientific rigor by highlighting the contextual needs, especially of underrepresented populations, making them protagonists in the process of social change. This article aims to present the application of a participatory research method, called Community-Based Participatory Research (CBPR), in a context of social vulnerability in southern Brazil. It seeks to discuss the challenges and strengths of the method, which provides ecological validity for the development of public policies appropriate to the context, while empowering the participants. The research has been carried out since 2019 and, among the inherent challenges, has also faced the difficulties posed by the COVID-19 pandemic. Based on the application of this method in Brazil, the importance of involving participants throughout the research process has been identified, so that policies are developed to meet the needs of the community and are sustained by those most interested.
Self-Care and Resilience in People with Diabetes Mellitus in the COVID-19 Pandemic
Authors: Binhardi Bárbara Aparecida , Torquato Maria Teresa da Costa Gonçalves , Scorsolini-Comin Fabio , Zanetti Maria Lúcia , Franco Laércio Joel , Teixeira Carla Regina de Souza
Published: December 2023

Abstract Isolation and social distancing imposed adjustments in the lifestyle of people with diabetes mellitus (DM), who are more likely to develop more severe forms of COVID-19. This study aimed to analyze the relationship between self-care and resilience in people with DM during the COVID-19 pandemic. This is an observational-cross-sectional web survey with 1,475 Brazilian adults with DM. An instrument of sociodemographic and clinical variables and the DSC and CD-RISC 10 scales were used from March to October 2020. An increase in average resilience was observed with increasing age and that it was higher among proper self-care behaviors. The highest averages of resilience were found for men, with T2DM, under oral medication, no change in DM control during the pandemic, those who had telemedicine consultations, and were isolated. The development of resilience is suggested as a protective factor in clinical practice in DM.