bluuebunny/crossref_metadata_2025 huggingface dataset:
Đặc điểm lâm sàng và đột biến gen RB1 ở bệnh nhân u nguyên bào võng mạc một mắt
Authors: Linh Đào Nguyễn Hà , Huy Nguyễn Văn , Văn Phạm Trọng , Khánh Trần Vân
Published: January 2023

U nguyên bào võng mạc (UNBVM), một bệnh ác tính nội nhãn thường được chẩn đoán ở trẻ em, phần lớn là do đột biến bất hoạt của cả hai alen của gen RB1. Chẩn đoán UNBVM chủ yếu dựa vào bệnh cảnh lâm sàng và cận lâm sàng. Đây là khối u không thể sinh thiết trước khi mổ cắt bỏ nhãn cầu do nguy cơ gây phát tán tế bào ác tính ra ngoài, do đó chẩn đoán hình ảnh và xét nghiệm di truyền có ý nghĩa quan trọng. Trong nghiên cứu này, 16 bệnh nhân bị bệnh một mắt cần cắt bỏ nhãn cầu cho thấy tuổi phát hiện trung bình là 26,3 ± 18 tháng. Triệu chứng đầu tiên hay gặp nhất là ánh đồng tử trắng với 81,3%. Đa số bệnh nhân mắc bệnh ở giai đoạn E (chiếm 93,7%) và có duy nhất 1 bệnh nhân có tiền sử gia đình (chiếm 6,3%). Tỷ lệ bệnh nhân bị bong võng mạc cao chiếm 56,3%. Nghiên cứu phát hiện 14 loại đột biến trên 12 bệnh nhân, trong đó có phát hiện cả đột biến trên exon (11/14) và đột biến vị trí cắt nối exon - intron (3/14). Trong 11 đột biến trên exon có 10 đột biến điểm (2 đột biến lệch khung, 7 đột biến tạo mã kết thúc và 1 đột biến sai nghĩa) và 1 đột biến mất đoạn lớn. Trong 14 loại đột biến, có 1 đột biến mới chưa được công bố.
THE INFLUENCE OF CONCRETE COMPRESSION ZONE ON THE SHEAR RESISTANCE OF REINFORCED CONCRETE BEAMS
Authors: NEVDAKH А. , KRIVITSKIY P.
Published: January 2023

The paper analyzes the effect of the compressed zone of concrete on the shear resistance of reinforced concrete flexible beams. The calculation models are considered, by which the contribution of the compressed zone of concrete to the total value of the shear resistance is further determined. The features of each model are described, and schemes and dependencies for calculating the transverse force in the compressed zone of concrete are presented. The experimental database of specimens is presented and the analysis by the considered calculation models is carried out. Varying parameters in the database are marked and the analysis by the obtained calculated values of transverse force in the compressed concrete strip by models is performed. The contribution of the transverse force in the compressed zone to the quantitative contribution to the shear resistance is indicated and appropriate conclusions are drawn on the models presented and the parameters considered.
ADSORPTION OF HEXAVALENT CHROMIUM FROM ADSORBATE USING EUCALYPTUS (EUCALYPTUS GLOBULES) AND SAKHU (SHOREA ROBUSTA) SAW DUST AS AN ADSORBENT
Authors: MISHRA ANOOP KUMAR
Published: January 2023

The present work deals with the removal of chromium from adsorbate solution using of Eucalyptus and Sakhu saw dusts. The adsorbent material for removal of chromium (VI) ion using fixed double packed adsorption column. The comparative study was done with both plants saw dust, in different pH, temperature, adsorbate concentration and different adsorbate concentrations. It was also observed that the maximum adsorption shows Sakhu saw dust is 91.66% as compared to Eucalyptus saw dust at 50 g adsorbent 50 ppm adsorbate solution with 27 oC temperature and pH 6.
A STUDY ON QUALITY EVALUATION OF MINIMALLY PROCESSED FRUITS AND VEGETABLES
Authors: K. MANJULA  , K. SOWJANYA
Published: January 2023

Today’s society characterized by an increasing health consciousness and growing interest in the role of food for maintaining and improving human well-being and consumer health, in addition to their nutritional and sensory properties, foods are currently recognized as active and protective agents. Among the others, fresh-cut horticultural products stand out as convenient novel foods that fit the many feeds of a modern life style as they combine technical content with an innovative food concept. The international fresh-cut produce Association (IFPA) defines fresh-cut products as fruits or vegetables that have been trimmed and / or peeled and / or cut in to 100% usable product that is bagged or pre-packaged to offer consumers high nutrition, convenience, and flavour while still maintaining its freshness. In particular, fresh cut fruits attract consumers because they are fresh, nutritious, low priced, and ready-to-eat. As a consequence, a wide assortment of minimally processed fruits has been developed to meet consumers, needs for ‘quick” and convenient products, and to benefit from fruits healthy image. Present study was carried out to known the microbiological quality of minimally processed fruits and vegetable. Acidty, pH and moisture content was estimated under physico-chemical properties and TPC and Yeasts and mouls count was analysed for minimally processed cabbge and Pineapple available in Tirupathi Super markets.
GEOCHEMICAL MODELING AND PRELIMINARY ASSESSMENT OF TRACE METALS CONTAMINATION IN GROUNDWATER AQUIFER OF GUNA DISTRICT, INDIA
Authors: SRIVASTAVA SUNIL KUMAR
Published: January 2023

Water is the most precious natural resource, which gets contaminated in the recent past through various anthropogenic activities. The study reveals that Guna district subsurface water gets contaminated by leaching chemical fertilizers used in agriculture. Nitrate is the principal ion released in groundwater due to the excess utilization of urea as chemical fertilizer in agriculture. Fluoride is also reported in subsurface water through the chemical weathering of CaF2 and other fluorite-rich minerals. Trace metals (Fe, Cu, Pb) are also reported in a few locations, affecting groundwater quality. A mathematical calculation has been performed to calculate the WQI value of the Guna district in this study. The interpretation of the WQI value for the study area indicates ~22.81% good water, ~71.14% poor water, and only ~5.37% very poor quality water.
THE TOXIC EFFECT OF AN ANIONIC DETERGENT ON A ROOTED FLOATING MACROPHYTE
Authors: NAIR1 LEKHA , GOPAL MADHU , A.P. THOMAS
Published: January 2023

In this study the toxic effect of a commonly used anionic synthetic detergent on the growth and biochemical characteristics of Nymphoides indica, a rooted floating macrophyte was evaluated for different concentrations. The effect was studied for a period of one month. The growth characteristics of the plant were assessed in terms of specific leaf area (SLA). Biochemical analysis was done for total chlorophyll content, total protein, membrane lipid peroxidation and electrolyte leakage from tissues. Chlorophyll Stability Index (CSI) and percent Membrane Injury (MI %) were also assessed. The results revealed that the anionic detergent inflicted adverse effects on all the parameters considered. Lipid peroxidation and electrolyte leakage serve as more relevant parameters for detergent induced stress.
CONSTRUCTION OF NEW $\Omega$-SPECTRUM AND THEIR APPLICATIONS TO COHOMOLOGY THEORY
Authors: Rana DrPravanjan Kumar , Mandal Bhaskar
Published: January 2023

The aim of this paper is to construct a new $\Omega-spectrum $ associated with infinite symmetric product functor of connected CW-complexes and their application to cohomology theory.\\ In this paper we studies all cohomology operation for the cohomology theory associated with new $\Omega$-spectrum.\\More precisely we prove that:\\i) the abelian group of all cohomology operations of degree k for the cohomology theory $H^*(\hspace{6pt};\underline{A})$ is isomorphic to the group $H^{n+k}(SP^{\infty}(\Sigma^n Y);\underline{A})$ ; and \\ii) the graded abelian group of all stable cohomology operations of degree k for the cohomology theory $H^*(;\underline{A})$ is isomorphic to the group $ \varprojlim H^{n+k}(SP^{\infty}(\Sigma^n Y);
A STUDY OF COVERING SPACES THROUGH LATTICES
Authors: Rana Dr. Pravanjan Kumar , Hossain Sarmad , Mandal Bhaskar
Published: January 2023

Let $C(X)$ denote the set of all covering spaces $(\tilde{X},\tilde{x},p)$ of $(X,x)$ where $(X,x)$ are path connected,locally path connected and semilocally simply connected pointed topological spaces.\\In this paper we show that:\\(i)$(C(X),\geq)$ is a lattice and $(C^r(X),\geq)$ is a subllatice of $(C(X),\geq)$ without assuming $\pi(X,x)$ is abelian,where $C^r(X)$ is the set of all regular covering spaces of $(X,x)$.\\(ii)$(C(X),\geq)$ is a modular,bounded and complete lattice when $\pi(X,x)$ is abelian.
Reconsidering Utopia from the Perspective of Cognitive-affective Schema
Authors: Yihan ZHENG , Yushuang ZHU
Published: January 2023

The complexity and ambiguity of Utopia make it a disputed concept in the academic field, resulting in an increasing need to redefine it. From the perspective of Cognitive-schematic theory, Utopia could be defined as an adaptive mechanism triggered by the lack of sense of security. Such a mechanism is in effect a cognitive-affective schema within which the individual could construct idealized time-space, social relations, identity and alternative values. Through such a cognitive-affective schema, the individual could find it possible to satisfy the needs of emotional regulation, happiness pursuit and even social reformation.
On the Translation of Chinese Classics from the Perspective of Medio-translatology
Authors: Chuanyin ZHENG
Published: January 2023

Translation is indispensable to cross-cultural communication. To render Chinese Classics into English and introduce them to the west is a vitally important commission of medio-translatology. Chinese Classics-the crystallization of ancient Chinese wisdom-convey the most prominent fine cultures of Chinese nations, reflecting the overall needs of humanity and contributing to the civilization of world as a whole. With Chinese economy skyrocketing currently and Chinese international statue rising constantly, it is a must for Chinese Classics to go global and converge itself into the world civilization, serving the construction of a shared future for mankind.
An Introduction to Vocal Fold Masses
Authors: Martha Vishnu , Vontela Swetha , Sataloff Robert
Published: January 2023

Vocal fold masses are common, and singing teachers should be familiar with their nature and implications. This article reviews common abnormalities that occur on the vocal folds including nodules, cysts, polyps, scar, vascular abnormalities, granulomas and other pathology. Each requires different management. Guidance is given so that singing teachers understand the nature of different vocal fold masses and basic treatment guidelines. This will help them advise their students as to whether treatment recommendations seem reasonable.
The Voice Divided: A Data Driven Analysis of Vocal Subcategorization
Authors: Feken Isaiah
Published: January 2023

Vocal subcategorization, or the practice of creating a specific vocal subcategory by adding a descriptor, i.e., dramatic, on to a primary vocal category, i.e., soprano, is both universal and contentious within the operatic world. Many factors attribute to the field’s contentious nature: there is no universal system of subcategorization or subcategory taxonomy; despite sharing both primary vocal categories, i.e., soprano, mezzo soprano, contralto, tenor, baritone, and bass, and using many of the same descriptors, i.e., dramatic, lyric, and comedic, no two taxonomies are considered analogues; only one taxonomy has a codifying document; and there are not date-driven analyses of any taxonomy. This document presents the first data-driven analysis of a major vocal subcategorization taxonomy, specifically the German taxonomy as outlined by the Handbuch der Oper (Kloiber, Konold, and Maschka; Bärenreither Verlag, Kassel, 2016), revealing new insights into the inner workings of the Handbuch specifically, as well as operatic genre more broadly.
Evaluation of the Level of Hetero Perception of the “T” Graft for the Management of Punta Nasal in a Group of Mexican Patients
Authors: Paz Alonso Mónica Mariana
Published: January 2023

Material and Method: Retrospective descriptive study of the records of patients operated on for rhinoplasty with T-graft placement. Seven independent specialists of recognized prestige in Nasal Surgery were asked to analyze the pre-surgical and post- surgical photographs at 20 weeks, and to carry out the evaluation. From each case, granting a score, the one that evaluated with the highest qualification and the one that evaluated with the lowest qualifications were eliminated. Objective: To determine the efficacy of the "T" graft for the management of the nasal tip in mestizo patients. Results: 22 cases were included in the analysis, 19 women and 3 men aged between 16 and 64 years. Only one case involved secondary surgery. Improvement was observed in the projection, rotation and definition of the tip in all cases, also observing improvement in the following: the wing-columnella ratio in 86.4%, symmetry in 92.7%, obtaining a natural appearance in 92.7%, the double columnar break in 86.3% and the obtaining of luminous points in 99%. No patient had significant tip asymmetry after the surgical procedure; No patient had postoperative complications or postoperative aesthetic or functional discomfort. Conclusions: The "T" graft can be used successfully in cases where it is necessary to increase the projection, definition and rotation of the nasal tip that cannot be achieved only by sutures or other types of grafts, it is especially useful in cases of skin thick, and being above the domes, favors a natural aesthetic result. In addition, it is a useful graft in cases of asymmetry of alar cartilages and for correction in some cases of the wing-columnella relationship.
Rhipicephalus sanguineus sensu lato (Ixodida: Ixodidae) attached to the ear canal and tympanic membrane of two children from Panama
Authors: Bermúdez Sergio E. , Morales Joan , Córdoba Antonio , Daza Carlos
Published: January 2023

In May 2022 and August 2022, two children, ten and 8-years old, respectively, were attended for foreign body sensation, pain, and discomfort in their ears. During the evaluation of the first case, a tick attached to his tympanic membrane was observed, whilst three ticks were evidenced in the ear canal and membrane tympanic of case 2. Ticks were identified as Rhipicephalus sanguineus sensu lato. Both patients came from urban places in the Chiriqui province, and ticks were found in their dogs. Moreover, additional clinical considerations of these cases and the relative importance of R. sanguineus s.l. are addressed.
DİJİTAL DÜNYADA ÇEVRİMİÇİ RİSKLER, BİLİŞİM SUÇLARI VE MAĞDUR ÇOCUK
Authors: ÖZKAYA Pelin
Published: January 2023

Çocuk, dünyada tehlikeye maruz kalmaya en müsait birey kuşkusuz. Tarihin tüm devirlerinde kaçırılan, öldürülen veya istismara uğrayan çocuklarla ilgili çok sayıda olayla karşılaşmaktayız. İnternetin olmadığı veya henüz evlere bu kadar yerleşmediği yıllarda, onları korumak fiziki alanlarla sınırlıydı. Dikkatli bir gözetim ve uzun demir parmaklıklı binalar güvenliği büyük ölçüde sağlıyordu ancak internetle birlikte tüm fiziki sınırlar ortadan kalkarak gözetim imkanı zorlaştı. Dünya’nın herhangi bir yerindeki herhangi bir kişi bir tık uzağımızda, hatta bazı zamanlarda evimizin içinde... Dahası, bilgisayarlar, cep telefonları ve tabletlerle o kişileri evimize kendimiz davet ediyoruz. Saldırganların giriş kapısı olarak kullandığı bu sistemler, çocukla ilgili kişisel verileri tehlikeye atarak gizlilik ihlaline neden olurken, istismar, kaçırma ve sömürü gibi fiillerin oluşumunu da tetiklemektedir. Dijital oyunlar sözü geçen tehlikeler için sosyal platformlarla birlikte en müsait alanları oluşturur. Bu mecralar çocukları kandırmak, manipüle etmek veya tehdit ya da şantajla sanal teması fiziki temasa dönüştürmek için kullanıldığı kadar, siber zorbalık, takip ve taciz eylemleri için de ideal araçlardır. Ailelerine veya öğretmenlerine yaşadıkları durumları anlatamayan veya hukuki olarak nereye başvurması gerektiğinin bilicinde olmayan çocuklar için sonucu telafi edilemeyen mağduriyetler doğmaktadır. Çocukları siber dünyanın tehditlerinden korumak için alınması gereken önlemler konusunda devlete büyük oranda iş düşmekle birlikte, temel eğitimin ve bilinçlendirmenin ailede başlayarak okulda devam ettiği unutulmamalıdır. Bu kapsamda bu makalede, çocukların dijital ortamda maruz kaldığı çeşitli tehlikeler anlatılarak hukuki çerçeve çizilecek ve alınması gereken tedbirlerden söz edilecektir.
FOUCAULT PERSPEKTİFİNDEN CEZALANDIRMA ANLAYIŞINDAKİ DEĞİŞİM
Authors: KAYA BOZOK Funda , KILIÇPARLAR Zeliha
Published: January 2023

Makalede Foucault özelinde cezalandırma anlayışındaki değişim incelenmektedir. Foucault’ya göre, cezalandırma pratiğindeki dönüşüm ile iktidarın dönüşümü arasında bir paralellik bulunmaktadır. Geleneksel iktidarın hâkim olduğu dönemde, cezalandırma suç işleyen kişinin bedeni üzerinde şiddetli bir azap çektirme şeklinde görülmekteydi. Bu dönemde cezanın amacı kralın, iktidarını yeniden tesis etmekti. İktidarın dönüşümü ile birlikte suç işleyen kişinin bedeni öze ulaşmak adına kapatılan ve disipline edilen bir beden olarak görülmeye başlanmıştır. Artık cezalandırma ile amaçlanan, suç işleyen kişileri üretken ve itaatkâr hale getirmek adına bedeni disipline etmektir. Tarihteki iktidar anlayışlarına göre ceza ve infaz rejimindeki bu değişimler, Foucault’nun çalışmalarından yola çıkılarak ele alınmıştır. Çalışmada suçlulara uygulanan aleni ve görkemli cezalandırma ayinlerinin yerini gözden uzakta ve sadece cezadan ibaret olmayan yeni tekniklere bırakılışı açıklanacaktır. Ayrıca azap çektirmekten, reform hareketlerinin gerçekleşmesiyle meydana gelen cezaların yumuşamasına, disiplinci iktidara ve onun en belirgin görüldüğü sistem olan panoptikona değinilmiştir. Son olarak hapishane sistemine dönüşümün nasıl gerçekleştiği ve iktidarın bu cezalandırma sistemlerinde nasıl göründüğü ele alınmıştır.
7406 SAYILI KANUN’UN SAĞLIK ÇALIŞANLARI BAKIMINDAN GETİRDİĞİ YENİ DÜZENLEMELER
Authors: KAYGUSUZ Serap
Published: January 2023

Türk Ceza Kanunu ve Bazı Kanunlarda Değişiklik Yapılmasına Dair 7406 sayılı Kanun ile, 3359 sayılı Sağlık Hizmetleri Temel Kanunu’nda hekimler ve diğer sağlık meslek mensupları bakımından önem arz eden değişiklikler yapılmıştır. Kamu veya özel sağlık kurum ve kuruluşları ile vakıf üniversitelerinde görev yapan hekimler ve diğer sağlık meslek mensuplarının tıbbî uygulama hatalarını konu edinen soruşturmalar hakkında özel izin prosedürü getirilmiştir. Soruşturma izni verme yetkisi ise yeni düzenleme kapsamında oluşturulan Meslekî Sorumluluk Kurulu’na verilmiş; Yükseköğretim Kanunu’nun 53. maddesinde yer alan soruşturma usulüne tabi olanlar bu düzenleme dışında tutulmuştur. Meslekî Sorumluluk Kurulu’na tazminat konusunda da görevler verilmiştir. Yeni düzenleme ile artık, kamuya ait sağlık kurum ve kuruluşları ile Devlet Üniversitelerinde görev yapan hekimler ve diğer sağlık meslek mensupları hakkında, idare tarafından ödenen tazminatların ilgiliye rücu edilip edilmeyeceğine ve rücu miktarına Meslekî Sorumluluk Kurulu karar verecektir. Bunun yanında Türk Ceza Kanunu’nda, takdiri indirim hükümleri konusunda, kasten öldürme ve kasten yaralama suçlarında, kamu hizmetlerinden yararlanma hakkının engellenmesi suçunda, sağlık çalışanlarını da ilgilendiren önemli değişiklikler yapılmıştır. Sağlık çalışanlarına yönelik şiddet eylemlerinin yaptırımları bakımından değişikliklere gidilmiştir. Ayrıca, sağlık kurum ve kuruluşlarında görev yapan personele karşı görevleri sırasında veya görevleri dolayısıyla işlenen kasten yaralama suçu, Ceza Muhakemesi Kanunu’nda yer verilen katalog suçlar arasına eklenmiştir.
COMMON LAW’DA “TRUST”IN KÖKENİ OLARAK İSLAMİ “VAKIF” KURUMU
Authors: YILDIRIMER Şahban
Published: January 2023

İslam kurumları tarihi açısından çok özel bir yeri olmayan ve diğer kurumlar gibi mütalaa edilen başka bir ifadeyle diğer kurumlardan çok daha fazla bir ilgi ve dikkati çekmeyen vakıf kurumu başta İngiliz hukukçular olmak üzere birçok bilim insanı için önemli bir ilgiye mazhar olmuş ve birçok araştırmaya konu olmuştur. Ancak bu kurumun doğrudan incelemeye konu olduğu zannedilmemelidir. Bu kurum İngiliz “trust” kurumu bağlamında araştırmalara konu olmuştur. Zira “trust” kurumunun İngiliz kurumlar tarihi içinde müstesna bir yerinin olması bu kurumun köklerini ve gelişim evrelerini araştırma ihtiyacı hissettirmişti. Bir başka husus da bu ve benzeri kurumların ilk ortaya çıktığı dönemlerin bahse konu bu toplumların çok ilkel denebilecek anlayışlara sahip olduğu dönemlere denk gelmesidir. Bir başka ifadeyle on ikinci yüzyıl gibi çok erken bir dönemde nasıl oldu da bu şekilde çok amaçlı bir kurum bu toplum tarafından ortaya çıkarıldı. Trust kurumunun özgün olduğu varsayımıyla hareket edenler bu kurumu common law hukuk düşüncesinin emsalsiz bir ürünü olduğunu ifade ederler. Bu perspektifle konuyu ele alanlar çok zaman kurumun menşeinden –bilinçli ya da bilinçsiz- ziyade fonksiyonlarına odaklanmayı önerirler. Böyle bir kurumun bir başka kültürden ilham alınarak oluşturulmuş olabileceğine ihtimal dahi vermek istemezler. Trust kurumunun İslam hukuk düşüncesinde izlerini araştıran hukukçuların bu konudaki kanaatlerini doğrulayacak yeterli argümanlara ulaştıklarını ifade etmek mümkündür. Ayrıca trust kurumunu çevreleyen kavram ağına baktığımız zaman İslam vakıf hukukuna ilişkin kavramların belirgin bir izdüşümünün varlığı kolayca fark edilecektir. Bu çalışmamızda bu denli önemli bir iddianın bilimsel zeminini irdeleyeceğiz.
HAKARETİN SUÇ OLMAKTAN ÇIKARILMASI VE İKAME YAPTIRIM ÖNERİSİ: ÖZEL HUKUK CEZASI
Authors: ORAL Tuğçe , BAŞ Eylem
Published: January 2023

5237 sayılı Türk Ceza Kanunu’nun (TCK) “Özel Hükümler” başlıklı “İkinci Kitabı”nın “Kişilere Karşı Suçlar”a ayrılan “İkinci Kısmı”nda ve “Şerefe Karşı Suçlar”a yer verilen “Sekizinci Bölümü”nde 125. maddede hakaret suçunun temel şekline ve daha fazla ceza verilmesini gerektiren nitelikli hallerine yer verildiği görülmektedir. Çalışmada, Türk hukuk sistemindeki mevcut haliyle hakaretin suç olarak düzenlenmesinin gerekli olup olmadığı TCK’nın 125. maddesinde yer alan genel hakaret suçlarıyla sınırlı olarak incelenmektedir. Nitekim karşılaştırmalı hukuka bakıldığında özellikle de basın yoluyla gerçekleştirilen hakaretin ifade özgürlüğüne getirdiği sınırlamalar sebebiyle suç olmaktan çıkarılması yönünde eğiliminin bulunduğu görülmektedir. Bu kapsamda yalnızca tazminatı gerektiren bir haksız fiil olarak düzenlenmesi yönünde öğretide de görüşler bulunmaktadır. Örneğin Anglosakson hukuk sisteminin geçmişten günümüze dek eğilimi, hakaret suçundan dolayı yargılamanın sınırlandırılması ve aşamalı bir şekilde bunun suç olmaktan çıkarılmasına yöneliktir. Bu kapsamda, çalışmada Türk hukuk sistemi bakımından hakaret davranışı değerlendirilerek hakaretin “suç” olmaktan çıkarılmasının gerekliliği üzerinde durulmakta ve ikame yaptırım önerisi olarak özel hukuk cezasının uygulanması önerilmektedir.
DETECTION OF GENETICALLY MODIFIED RICE LOCALLY AVAILABLE IN PUNJAB, PAKISTAN
Authors: LATIF A , SHAFIQUE MT , BANO M , BIBI A , BIBI T , GULNAZ S , KHAN RAR , MALHI AR , SARFRAZ S , AHSAN A , IQBAL HMN , LATIF A , NAZAR MZK , ASIF M
Published: January 2023

Rice (Oryza sativa L.) is an important cereal crop that provides food to half of the world's population. Pakistan's traditional and premium quality rice is mostly exported to Europe. Transgenic or genetically modified rice (GM RICE) has been developed in the USA, China, and other countries, like herbicide-tolerant Liberty-Link rice (LLRICE06, LLRICE62, LLRICE601) and insect-resistant Bt-63. International and national biosafety regulations allow countries to stop the import of any genetically modified organism (GMO) due to its possible safety concerns. PCR-based methods are recommended for the accurate detection of GM rice. Qualitative PCR is used to detect the presence or absence of GMOs in a rice sample. The objective of this study was to check the presence of GMOs in the rice samples collected from rice-growing areas in Punjab. Eighty-two rice samples were collected randomly from various markets/locations in rice-growing areas of Punjab for this study. Twelve bulks were prepared to represent eighty-two rice samples. The CTAB method was used to extract the DNA from rice samples to analyze it. PCR of rice bulk samples was performed using primers specific for SPS, CP, p35S, tNOS, nptII, Hpt and Bt 63 rice. Positive and negative controls were included in each PCR. Primers specific for chloroplast (CP) and Sucrose phosphate synthase (SPS) genes were used to confirm DNA quality for amplification. Then, primers specific for the cauliflower mosaic virus (CaMV) 35S promoter and the Agrobacterium nopaline synthase (NOS) terminator were used for the detection of GM rice through PCR, neomycin phosphotransferase II (nptII) and Hygromycin phosphotransferase (Hpt) were used as a selectable marker and Bt 63 rice was used in insect resistance. The gel electrophoresis of PCR was conducted using a DNA ladder and then taking of the image was through gel documentation system for visualization and analysis. According to the results, all the rice bulks representing the eighty-two rice samples were negative for p35S, tNOS, nptII, Hygro and Bt 63 rice event. These findings are encouraging and demonstrate that rice grown in kalar track of Punjab, Pakistan, is non-GMO. Such surveillance and monitoring would be largely beneficial to maintain the purity of our traditional non-GM rice and to avoid any possible mixing of GM rice seeds, especially at the time of import. All these efforts will ensure and protect our national share in the international trade of rice.
SOME ECONOMIC INDICATORS OF INDUSTRIAL GARDENING IN ARMENIAN-POPULATED AREAS IN THE EAST OF ARMENIAN HIGHLANDS BETWEEN 1806-2018: FRUIT GROWING AND VITICULTURE
Authors: Beketovski D. , Hayrapetyan A. , Mamajanyan S. , Tumanyan K.
Published: January 2023

For the first time, the article presents the economic data of industrial fruit growing and viticulture of the region over the past two hundred years. Calculations were carried out according to five parameters: the total and fruiting areas of the gardens, the gross yield of the entire and fruiting area, as well as the yield. The results of statistical processing of the given data reasonably indicate their sufficient scientific reliability.
THE CURRENT STATE AND IMPROVEMENT OF IRRIGATED MEADOWS GRAY LANDS OF THE SUB-ARAKS SUBZONE IN THE ARARAT VALLEY/ԱՐԱՐԱՏՅԱՆ ՀԱՐԹԱՎԱՅՐԻ ՄԵՐՁԱՐԱՔՍՅԱՆ ԵՆԹԱԳՈՏՈւ ՄԱՐԳԱԳԵՏՆԱՅԻՆ ԳՈՐՇ ՈՌՈԳԵԼԻ ՀՈՂԵՐԻ ՆԵՐԿԱ ՎԻՃԱԿԸ ԵՎ ԲԱՐԵԼԱՎՄԱՆ ՈւՂԻՆԵՐԸ
Authors: Baghdasaryan S. , Daveyan S. , Barseghyan M. , Ashkaryan H.
Published: January 2023

The research was carried out in the administrative area of Lusagyugh settlement, Araks community, Armavir region, RA, at an altitude of 850 m above sea level. About 2.5 hectares (1.2 hectares of alfalfa and 1.3 hectares of uncultivated areas) of arable land were surveyed. The area is located in the semi-desert gray irrigated lands.
Land-based fish farms have been built on the adjacent arable land. The studied land is intended for cultivation of perennial plantations. For this purpose, field and laboratory studies were conducted to study the soil quality characteristics of the land, and four soil plots were installed in the typical areas.
Through each land plot, the description of the land layers was given in depth, and through the latter, the description of the adjacent area.
The researches revealed the degree of fertility of the studied lands and the ameliorative condition, on the basis of which the ways of improvement and cultivation opportunities were developed./
Հետազոտությունները իրականացվել են ՀՀ Արմավիրի մարզի «Արաքս» համայնքի Լուսագյուղ բնակավայրի վարաչական տարածքում՝ ծովի մակերևույթից 850 մ բարձրության վրա: Հետազոտվել է շուրջ 2,5 հեկտար (1,2 հա՝ առվույտ և 1,3 հա՝ անմշակ) վարելահող: Տարածքը գտնվում է կիսանապատային գորշ ոռոգելի հողերի տարածման գոտում:
Հետազոտվող հողատարածքը նախատեսվում է օգտագործել բազմամյա տնկարկների մշակության համար:
Այդ նպատակով հողատարածքի հողի որակական հատկանիշների ուսումնասիրության համար կատարվել են դաշտային ու լաբորատոր հետազոտություններ. տեղանքին բնորոշ հատվածներում տեղադրվել են չորս հողային կտրվածքներ:
Յուրաքանչյուր հողային կտրվածքի միջոցով ըստ խորության տրվել է հողաշերտերի նկարագիրը և վերջինիս միջոցով՝ նրան հարակից տարածքի բնութագիրը:
Կատարված հետազոտություններով պարզվել է հետազոտվող հողերի բերրիության աստիճանը և մելիորատիվ վիճակը, որի հիման վրա մշակվել են բարելավման ուղիներն ու մշակության հնարավորությունները:
Entre foguetes, estrelas e canetas:
Authors: Sant'Anna Hugo Cristo
Published: January 2023

Nos últimos 20 anos, as temáticas do design computacional e generativo tornaram-se mais presentes nos interesses e práticas de estudantes de Design. Entretanto, persistem barreiras para a aprendizagem dos princípios, conceitos, práticas e perspectivas da Computação por esses estudantes, tais como a falta de fundamentos teóricos e dificuldades de uso dos ambientes de programação criados para outras áreas. Este artigo apresenta um relato de experiência de ensino de princípios da Computação no Curso de Design da Ufes, utilizando uma abordagem de ensino e ambiente específicos para este público. Por dois semestres, um total de 150 estudantes testaram a proposta e produziram cerca de 2600 programas, cujas estruturas e funcionamentos ilustram processos de resolução de problemas no âmbito da abordagem didática. Os resultados preliminares sugerem que a abordagem promoveu a aprendizagem de conceitos da Computação, fomentou colaboração entre os aprendizes e oportunizou a expressão individual por meio da programação.
Atos cotidianos de design:
Authors: Anastassakis Zoy , Martins Marcos
Published: January 2023

Este artigo apresenta reflexões para uma reavaliação crítica do campo do design a partir do agravamento de uma crise na educação pública que atingiu a Escola Superior de Desenho Industrial nos anos de 2016 a 2018. Com salários e bolsas suspensos ou atrasados, professores, alunos, funcionários técnico-administrativos se uniram a ex-alunos e amigos da escola com o propósito de desenvolver atividades que pudessem manter a escola aberta. A partir dessa mobilização coletiva, emergem questões a respeito do fazer design e da educação em design que suscitam uma reconfiguração de práticas e pressupostos do campo. Mais especificamente, reivindica-se a qualificação de atos cotidianos de sobrevivência como atos de design, de um fazer design sem projetar e sem o compromisso com soluções para o futuro. Dessa forma, os conceitos de planejamento, progresso e futuro, tradicionalmente ligados ao campo, são questionados em busca de alternativas para um projeto de futuro desenvolvimentista e racionalista que é problematizado em diversos campos de produção teórica contemporânea.
Transmissão do saber fazer cerâmico por mestre artesão:
Authors: Silva Germannya D’Garcia , Andrade Ana Maria de , Tabosa Tibério , Cavalcanti Virginia
Published: January 2023

O artigo relata o processo de desenvolvimento e execução do projeto cultural Cerâmica nas Escolas: oficina de transmissão de saberes no Cabo de Santo Agostinho PE, cujo objetivo foi transmitir o conhecimento da produção em cerâmica vermelha por variadas práticas de modelagens, ministrada por mestre artesão ceramista, para sua própria comunidade. Pautado pelas premissas de sustentabilidade nas dimensões sociais, culturais, econômicas e produtivas e, ao mesmo tempo, assumindo o Centro de Artesanato Arquiteto Wilson Campos Júnior como comunidade criativa; a ação sensibilizou 50 jovens, com idade entre 12 e 16 anos, estudantes da Escola Municipal Professor Jason Brandão, para a importância e valorização da atividade artesanal tradicional da localidade, bem como ampliou as perspectivas de formar novas gerações de ceramistas. Esta ação, reforça a importância de ações articuladas de pesquisa, ensino e extensão e das parcerias entre a Prefeitura, Universidade e Comunidade.
On the problem of optimizing emissions of industrial enterprises
Authors: A.B. Sadigov, , L.Sh. Gadimova, , S.Y. Guliyeva, , L.G. Najafova, , T.A. Isazade,
Published: January 2023

The problem of optimization of emissions of industrial enterprises is solved, taking into account the minimum dose of pollution of environmentally significant zones. Economic costs for reorganization of technology of the considered industrial objects are taken as the main criterion so that the total economic costs for the given reduction of pollution would be minimal for the enterprises for the whole region. As a result, the problem is reduced to a linear programming problem using solution of basic and conjugate equations of transport and diffusion of polluting aerosols.
THE IMPACT OF JUST IN TIME STRATEGY AND PULL CHAIN STRATEGY ON SUPPLY CHAIN PERFORMANCE
Authors: Hamadneh Samer , Alshurideh Muhammad , Al Kurdi Barween , AlHamad Ahmad
Published: January 2023

Businesses used to be able to compete successfully as standalone entities, but in order to get an effective organizational performance, they need to compete as an essential link in a supply chain performance. For supply chain management to be successful, both internal and external integration are required of operational procedures across the supply chain performance. Therefore, just in time and pull chain strategy incorporated to assess the supply chain performance and found as significant to enhance the supply chain performance by meeting customer demands.
IMPACT OF CHANGE MANAGEMENT AND COMMUNICATION ON BUSINESS PROCESS MANAGEMENT
Authors: Alrawabdeh Wasfi , Alshurideh Muhammad , Akour Iman , Al Kurdi Barween
Published: January 2023

The teams that are employed by the firm impacted by the implemented change, whether it is a change in technology, leadership, or processes. Through education and acceptance of the need for change, change management strives to move these teams from the present condition to the future state. Business process management is the association of management and IT, and it defines methodologies, strategies, and tools that let the business plan, implement, monitor, and evaluate its operational business processes. Therefore every business require change within the business operations to maintain competitive advantage. Effective communications has a core value in maintaining an adaptable change to the workforce and easy to acquire. This research is providing the subsequent set of knowledge to the business practitioners and addition to the literature of business studies.
THE IMPACT OF PROCESS REDESIGN AND AGILE OPERATIONS ON IMPROVING THE QUALITY IN THE SERVICE COMPANIES
Authors: Alshurideh Muhammad , Alrawabdeh Wasfi , Al Kurdi Barween , Hamadneh Samer
Published: January 2023

Rapidity, reactivity, cost effectiveness, adaptability, and an improvement in the productivity of goods and services are the main goals of the agile supply chain. Over the past 2 decads, the manufacturing and service industries have paid growing attention to this subject as agile businesses offer higher service levels with reduced inventories. The literature on agile operations and business process redesign in the service industries is analyzed in this research. It maps earlier studies in this area across a variety of journals, institutions, and nations. Business process redesign and agile operations are acknowledged as a way to help businesses accomplish fully value-added changes or to increase efficiency. The primary goal of this research is exploring impact of process redesign and agile operations implementations for improvement to increase service quality.
IMPACT ON TRANSPORTATION FLEXIBILITY ON ECONOMIC GROWTH AT UAE’S MARITIME INDUSTRY
Authors: Alshurideh Muhammad Turki , Al Kurdi Barween , Al-Okaily Manaf , Hamadneh Samer
Published: January 2023

The proximity to actions, employment prospects, and other opportunities gives modern cities a social edge and increases the economic growth. These cities are growing into complex, fragmented systems. Thus, promotion of sustainable and shared transportation options, the enhancement of social fairness, health, city resilience, and the efficiency of rural and scattered parts are some of the major difficulties facing transportation planning. This research is subjected to highlight the impact of transportation flexibility on economic growth. Findings revealed transportation flexibility is a cost effective way to promote transportation in the city as well as the increase in economic development.
IMPACT OF DISTANCE LEARNING TECHNOLOGY ON ONLINE EDUCATION PERFORMANCE
Authors: Alshurideh Hevron , Alshurideh Muhammad , Al Kurdi Barween , Alkurdi Shireen
Published: January 2023

Distance learning technologies have become mainstream due to the emergence of coronavirus (COVID-19) and its variants over the last few months. Both companies and institutions are now resorting to using technology for their operations, whether to train their workforce or educate their students. This research has devised full stack distance learning technology platform to enable a factious educational institutions or corporation to enable its usage and effectively demonstrate how technology could be utilized to fully transform learning online. As a result, the functioning of how a university or learning institution could take their learning online away from their physical medium, thereby insulting themselves from the risk of suffering contagion due to the coronavirus while continuing their operations and business as usual.
Emerging Communication Gap to the Lives of Differently Abled Individuals Working in a Blind Massage Service
Authors: Sumalinog Edilberto , Sambrana Geraldine , Diaz Welou Dil , Bebero Lucia Krylen
Published: January 2023

This study was conducted specifically for those blind and with impaired vision and to perform an analysis of the communication gap between the blind masseurs working in massage parlors that critically affects their being because of their disability and the specific limitations they encounter in their everyday life at work and including at home and in their respective communities. Communication can be difficult even with ordinarily-sighted people; it can be challenging for visually-impaired people. However, when both parties are aware of the barriers to communication, productive conversation between normally-sighted and visually-impaired people is still possible. People with visual impairments are already used to living without sight. Frequently, visually-impaired individuals are victims of discrimination, whether intentionally or accidentally. In Howard Giles’ Theory of Communication and Accommodation, he described convergence as how we adapt or alter our communication behavior to become more like someone. This happens when a person decides to fit in and become part of their conversation partners. Further, the purpose of this study was to reconnoiter the emerging problems encountered by differently-abled individuals working as massage therapists. The study utilized a single-case qualitative research method to obtain information regarding the problems faced by differently-abled individuals working in blind massage services. Based on the testimonies gathered from the informants, the blind reading literacy barrier was perceived as a communication challenge among the employees. Their disability in reading makes their emotions unstable, causing doubts or fear of trust and confidence when they are required to affix a thumbprint instead of their signature on whatever document they are given to them.
Five Hundred and Sixty Years of Legal Regulation of Pharmacy in Bosnia and Herzegovina
Authors: Catic Tarik , Skrbo Armin , Masic Izet
Published: January 2023

Background: The rich history of pharmacy in Bosnia and Herzegovina has been sporadically dealt with systematically, except by enthusiasts and researchers. The only book on this topic was published in 1958, and after the aggression against Bosnia and Herzegovina, the history of pharmacy was treated mainly as part of the history of medicine. The lack of a culture of memory and a systematic approach to historical heritage brought together a group of experts who deal with this topic in more detail and collect available historical relevant material. Pharmacy as a highly regulated health discipline also in Bosnia and Herzegovina is a legacy of legal acts and documents that depict different periods and the development of pharmacy itself under the influence of circumstances and legislation. Objective: The aim of this paper is to show the development of legislation related to the pharmaceutical sector in Bosnia and Herzegovina through the historical periods of its development. Methods: This is retrospective research based on internet sources, archives and publications available in libraries. Results and Discussion: The available legal regulations and documents through five periods of pharmaceutical development were analysed, from which it can be concluded that the organization of the pharmaceutical industry and its development over time remained stricter. Legal regulations depict the role of pharmacy in the health system, but they also represent sources for further research in this area, and constitute important historiographical material. The analysis of legal regulations speaks volumes about the way pharmaceutical activity is organized, so it is possible to follow the appearance of the first pharmacies, pharmacists, requirements for the quality of medicines, production and the modern role of pharmacists in the health system. Pharmaceutical legislation will certainly be the subject of future negotiations on the accession of Bosnia and Herzegovina to the European Union, and harmonization with the acquis of the EU is expected in the coming period.
Adverse drug reactions of oral non-steroidal anti-inflammatory drugs and its fixed drug combinations: A 5-year retrospective observational study
Authors: Gade Ramani , Patil Shivaraj , Patil Pooja , B Raghuveer
Published: January 2023

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are very commonly prescribed worldwide. Due to this, the incidence of adverse drug reactions (ADRs) to NSAIDs is increased.

Aims and Objectives: This study aims to analyze the ADRs reported to NSAIDs. Patient demographics, organ system affected severity of ADRs, and their causal association with the drug will be studied.

Materials and Methods: It was a retrospective analysis of ADRs reported to oral NSAIDs and its combinations over a period of 5 years from January 2015 to December 2020. Prior ethics committee approval was obtained. These ADRs were collected as part of pharmacovigilance activities.

Results: A total of 100 ADRs were reported due to NSAIDs. Most ADRs due to NSAIDs were reported in 30–39 years age group. Female gender was most affected by ADRs. Diclofenac was the most common NSAID causing ADRs. Skin and subcutaneous organ system was most affected. Six ADRs were reported as serious. Sixty-seven ADRs were categorized as probable using the World Health Organization causality assessment scale.

Conclusion: NSAIDs are commonly prescribed drugs. Analyzing the ADRs reported to NSAIDs will help in finding the risk factors. Based on this knowledge, rational prescription of NSAIDs can be done which will improve the patient safety.
PUBLIC PRIVATE PARTNERSHIP DALAM PROGRAM PENINGKATAN KOMPETENSI TENAGA KERJA DAN PRODUKTIVITAS (PKTKP) BERBASIS PEMAGANGAN DALAM NEGERI DI PROVINSI LAMPUNG
Authors: Sulistiowati Rahayu , Prihantika Ita , Asmiati
Published: January 2023

The domestic apprenticeship program in Lampung Province still encounters problems, such as the socialization process that is carried out less than optimally so that only a few companies are interested in collaborating. As a result, the company's recruitment implementation has not been able to achieve the specified target. This study aims to evaluate the implementation of the domestic apprenticeship program and identify the factors supporting and inhibiting the implementation of the domestic apprenticeship program in Lampung Province. The study was conducted with a qualitative descriptive approach using 3 indicators of the implementation of public private partnership (Public Private Partnership) consisting of policies, resources and communication (Kurniawan, Setianto et al., 2009). The results of this study indicate that the cooperation between the government and the private sector (public private partnership) in the program to increase labor competence and productivity (PKTKP) based on domestic apprenticeship in Lampung Province is quite effective. Viewed from the policy aspect, it can be said that it is effective because the purpose of holding this program is in accordance with the objectives of the government-private partnership which is beneficial in addition to providing services to the public but also providing benefits from companies that collaborate with the Lampung Province Manpower Office. In the aspect of resources, human resources in the implementation of this domestic apprenticeship program have not been maximized in achieving the desired target/results so that the resource aspect in this focus can be said to be less effective. In the communication that took place quite well, this was seen from the lobbying process to achieve the target of absorption of participants, although communication in the socialization process for recruiting companies had not yet reached the target.
EKSISTENSI BADAN PERENCANAAN PEMBANGUNAN DAERAH DALAM MENGELOLA ASPIRASI MASYARAKAT
Authors: Djafar Franky
Published: January 2023

This study aims to determine the ability of the Regional Development Planning Agency in absorbing community aspirations in development planning, and the factors that support and hinder it. This research uses qualitative by taking the research setting or location in Gorontalo Regency. Data collection techniques were carried out using interviews, observation and documentation. Data analysis in this study used analytical techniques with interactive patterns. The results of the study show that the Development Planning Agency still has difficulties in accommodating and accommodating community aspirations through the development planning system so that the results have not been able to fulfill all existing aspirations. in the form of communication has not been able to support the management of community aspirations to run well. Factors supporting the Regional Development Planning Agency in absorbing community aspirations are coordination between stakeholders, availability of information technology, stakeholder participation, and the authority possessed by the institution. While the inhibiting factors are the capabilities and skills of the apparatus, the minimum quality of apparatus resources, political intervention from the authorities, elite domination in setting programs, and the low quality of proposals from the community.
KUALITAS PELAYANAN TERHADAP KEPUASAN PELANGGAN DAN DAMPAKNYA PADA LOYALITAS PELANGGAN PERUSAHAAN TRANSPORTASI UMUM
Authors: Pangaribuan Nelson S. , Yenita
Published: January 2023

Adanya perubahan perilaku mobilisasi masyarakat dari penggunaan kendaraan pribadi menuju penggunaan transportasi umum mengindikasikan munculnya peluang yang baik bagi perusahaan di bidang transportasi umum. Penelitian yang dilakukan ini untuk mengetahui adanya dampak kualitas pelayanan terhadap kepuasan dan efeknya pada loyalitas pelanggan PO Bus Damri. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif. Sampel penelitian yang ditetapkan adalah penumpang di wilayah DKI Jakarta yang menggunakan jasa PO Bus Damri di tahun 2020 hingga 2022. Adapun sampel penelitian yang terkumpul dan memenuhi persyaratan adalah sebanyak 70 sampel. Data yang telah dikumpulkan kemudian dianalisis dengan analisis jalur. Hasil penelitian menunjukkan bahwa kualitas pelayanan memiliki pengaruh besar dan positif terhadap kepuasan pelanggan; kualitas pelayanan memiliki pengaruh signifikan dan positif terhadap loyalitas pelanggan; kepuasan pelanggan memiliki pengaruh signifikan dan positif terhadap loyalitas pelanggan, serta; kualitas pelayanan memiliki pengaruh signifikan terhadap loyalitas pelanggan melalui kepuasan pelanggan pada PO Bus Damri.