bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: A Rhodium‐Catalyzed Heterocycloaddition Route to 5‐Fluoroalkyl Substituted 1,3‐Oxazoles.
Authors: Wang Yanli , Zhu Shizheng
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Organofluorine Compounds and Fluorinating Agents. Part 27. New Trifluoromethyl Substituted 1,2,3‐Triazoles Linked to D‐Galactose and D‐Gulose.
Authors: Hager Christian , Miethchen Ralf , Reinke Helmut
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Tribenzo[b,e,i][1,6,7]trioxaphenalene and [1]Benzopyrano[2,3‐d]dinaphtho[2′,1′‐b; 1′′,2′′‐g]oxocine from 4‐Oxo‐4H‐1‐benzopyran‐3‐carboxaldehyde.
Authors: Bandyopadhyay C. , Sur K. R.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Syntheses of a Novel 5‐Thia‐1‐azacycl[3.3.2]azine Ring System and 3H‐1,4‐Diazacycl[3.3.2]azine Derivatives.
Authors: Kawamoto Tetsuji , Tomimatsu Kiminori , Ikemoto Tomomi , Abe Hidenori , Hamamura Kazumasa , Takatani Muneo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Synthesis of Anellated Pyridines from β‐Formyl Enamides under Microwave Irradiation.
Authors: Sharma Utpal , Ahmed Shahadat , Boruah Romesh C.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: [4 + 2] Cycloaddition Reaction of 3‐Hydrazono‐1,1,1‐trifluoro‐2‐alkanones to 4,5‐Bis(trifluoromethyl)pyridazines.
Authors: Kamitori Yasuhiro
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Potassium Channel Activators. Part 3. Synthesis and Pharmacological Evaluation of 3,4‐Dihydro‐2H‐1,4‐benzoxazine Derivatives: Modification at the 2 Position.
Authors: Matsumoto Yuzo , Uchida Wataru , Nakahara Hideaki , Yanagisawa Isao , Shibanuma Tadao , Nohira Hiroyuki
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis and Binding Characters of 1,3‐Bis(uracil‐1/3‐ylmethyl)benzene Based Acyclic and Cyclic Receptors.
Authors: Kumar Subodh , Paul Dharam , Singh Harjit
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Metal Ion Complexation Studies of Proton‐Ionizable Calix[4]azacrown Ethers in the 1,3‐Alternate Conformation.
Authors: Kim Jong Seung , Shon Ok Jae , Ko Jong Won , Cho Moon Hwan , Yu Ill Yong , Vicens Jacques
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1,4‐Diionic Organophosphorus Compounds. Stereoselective Synthesis of Dialkyl 2‐(1,1,1,5,5,5‐Hexafluoro‐2,4‐dioxopentane‐3‐yl‐3‐yide) ‐3‐triphenylphosphoniobutane‐1,4‐dioates.
Authors: Shaabani Ahmad , Teimouri Mohammad Bagher , Yavari Issa , Arasi Hassan Norouzi , Bijanzadeh Hamid Reza
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Expeditious Entry to the Hydrophenalene Ring System of Pseudopterosins.
Authors: Benoit‐Marquie Florence , Csaky Aurelio G. , Esteban Gema , Martinez M. Eugenia , Plumet Joaquin
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Diastereocontrolled Synthesis of the C1—C25 Domain of Sanglifehrin A.
Authors: Duan Maosheng , Paquette Leo A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Highly Fluorinated Dipeptide Building Blocks.
Authors: Koksch Beate , Muetze Kerstin , Osipov Sergej N , Golubev Alexander S. , Burger Klaus
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Diethers Derived from Dianhydrohexitols by Phase Transfer Catalysis under Microwave.
Authors: Chatti Saber , Bortolussi Michel , Loupy Andre
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses of Fluorescence‐Labeled Artificial Leaf‐Opening Substances, Fluorescent Probe Compounds Useful for Bioorganic Studies of Nyctinasty.
Authors: Ueda Minoru , Sawai Yoshiyuki , Yamamura Shosuke
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Norbornyl Route to Cyclohexitols: Stereoselective Synthesis of Conduritol‐E, allo‐Inositol, MK 7607 and Gabosines.
Authors: Mehta Goverdhan , Lakshminath Sripada
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies on Sialoglycoconjugates. Part 114. The First, Highly Efficient Synthesis of Spacer‐Armed O‐Glycans on GlyCAM‐1 and PSGL‐1: The Counter‐Receptors for L‐ and P‐Selectin.
Authors: Otsubo Nobumasa , Ishida Hideharu , Kiso Makoto
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Anomeric Reactivity‐Based One‐Pot Oligosaccharide Synthesis: A Rapid Route to Oligosaccharide Libraries.
Authors: Ye Xin‐Shan , Wong Chi‐Huey
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unexpected One‐Pot Epoxy Sulfone—Enaminone Transformation. Synthesis of 5a‐Carba‐β‐mannopyranosylamine.
Authors: Acena Jose Luis , Arjona Odon , Manas Rosa , Plumet Joaquin
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Glycosylations of a Family of 6‐Deoxy‐1,2‐glycals Generated by Catalytic Alkynol Cycloisomerization.
Authors: McDonald Frank E. , Reddy K. Subba , Diaz Yolanda
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure Elucidation and Chiral‐Total Synthesis of a New Indole Alkaloid, (‐)‐9‐Methoxymitralactonine, Isolated from Mitragyna speciosa in Malaysia.
Authors: Takayama Hiromitsu , Kurihara Mika , Kitajim Mariko , Said Ikram M. , Aimi Norio
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Highly Efficient Synthesis of L‐β‐2′‐Deoxy‐4′‐thio‐1′‐purine Nucleosides as Potential Antiviral Agents.
Authors: Kim Hea Ok , Jeong Lak Shin , Lee Sun Nan , Yoo Soo Jeong , Moon Hyung Ryong , Kim Kil Soo , Chun Moon Woo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Calonyctin A2, a Macrolidic Glycolipid with Plant Growth‐Promoting Activity.
Authors: Furukawa Jun‐ichi , Kobayashi Shigeru , Nomizu Motoyoshi , Nishi Norio , Sakairi Nobuo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural Characterization of Gentiobiosyl Diglycerides from Bacillus pumilus Associated with Ascidia Halocynthia aurantium.
Authors: Kalinovskaya N. I. , Kuznetsova T. A. , Kalinovsky A. I. , Denisenko V. A. , Svetashev V. I. , Romanenko L. A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rhodium(I)‐Catalyzed Addition of Phenols to Dienes. A New Convergent Synthesis of Vitamin E.
Authors: Bienayme Hugues , Ancel Jean‐Erick , Meilland Pierre , Simonato Jean‐Pierre
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies on Spongistatins: Synthesis of the C29—C44 Fragment.
Authors: Samadi Mohammad , Munoz‐Letelier Christian , Poigny Stephane , Guyot Michele
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Allyltitanation. Application to the Synthesis of Lactone Units Related to Compactin and Mevinolin.
Authors: Bouzbouz Samir , Cossy Janine
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Model for Combinatorial Organic Chemistry.
Authors: El‐Basil Sherif
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rare Earths 1999
Authors: several authors several authors
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural and Spectroscopic Aspects of Complexes Containing Terminal Technetium Oxo and Nitrido Multiple Bonds
Authors: Baldas John , Ivanov Zlata
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intercalation Compounds of Aluminum Hydroxide
Authors: Isupov V. P.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phase Equilibria and Layered Phases in the Systems A2X3—M2X3—M′X (A: Ga, In; M: Trivalent Metal; M′: Divalent Metal; X: S, Se)
Authors: Haeuseler H. , Srivastava S. K.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Interaction of Chromium(VI) Compounds with Organic Bases, Organic Acids, Amino Acids, Peptides and Other Molecules
Authors: Gili Pedro , Lorenzo‐Luis Pablo A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Growing Synthetic Utility of Weinreb′s Amide
Authors: Singh Jaimala , Satyamurthi N. , Aidhen Indrapal Singh
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gemini Surfactants
Authors: Menger Fredric M. , Keiper Jason S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stable Versions of Transient Push‐Pull Carbenes: Extending Lifetimes from Nanoseconds to Weeks
Authors: Buron Christophe , Gornitzka Heinz , Romanenko Vadim , Bertrand Guy
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Donor‐Substituted Silylenes: From Gas‐Phase Reactions to Stable Molecules
Authors: Heinicke J. , Oprea A. , Meinel S. , Mantey S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of Novel Carbocycle Forming Reactions Using Vinyl Selenides
Authors: Yamazaki Shoko
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Developments in Strained Cyclic Allenes
Authors: Balci Metin , Taskesenligil Yavuz
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Influence of the Polymer Chain on the Catalysis by Variable Valency Metal Complexes
Authors: Artemov A. V. , Vainstein E. F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: FR901228: Antineoplastic Antibiotic
Authors: Wang Hwa‐Chain R.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Peptide Receptors: Noncovalent Interactions Involving Peptides
Authors: Schneider Hans‐Jorg , Eblinger Frank , Sirish Mallena
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: (E)‐Alkene Peptide Bond Isosteres by Cuprate Opening of Vinyl Aziridines
Authors: Henninger Todd C. , Wipf Peter
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis of Labeled Sterols
Authors: Kovganko N. V. , Ananich S. K.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Di‐ and Polyfunctional Organomagnesium Compounds
Authors: Bickelhaupt F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure, Function and Potential Therapeutic Importance of NMDA‐Receptors. Part 1. Architecture and Modulation of the Receptors
Authors: Stark Holger , Grassmann Sven , Reichert Ulrich
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Innovative Biofilm Treatment Technologies for Water and Wastewater Treatment
Authors: Lazarova Valentina , Manem Jacques
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Strain and Structure of Sterically Congested Triplet Carbenes
Authors: Tomioka Hideo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mechanistic Features of the Reactions of Organomagnesium Compounds
Authors: Holm Torkil , Crossland Ingolf
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Current Status of the Application of Ionizing Radiation to Environmental Protection. Part 3. Sewage Sludge, Gaseous and Solid Systems
Authors: Pikaev A. K.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Protein Nuclear Magnetic Resonance Spectroscopy in the New Millennium
Authors: Pfuhl M. , Driscoll P. C.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Resolution Selenium Solid State NMR Spectroscopy as a Tool for Structural Studies of Organoselenium Compounds
Authors: Potrzebowski Marek J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spectral and Theoretical Studies on Thione—Thiol Tautomerism of N‐Containing Heterocycles
Authors: Stoyanov Stefan , Stoyanova Tatyana , Akrivos Pericles D.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Weakly Bonding Interactions in Organochalcogen Chemistry
Authors: Vargas‐Baca Ignacio , Chivers Tristram
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient and Facile Routes to Nitrones
Authors: Katritzky Alan R. , Cui Xilin , Long Qiuhe , Yang Baozhen , Wilcox Allan L. , Zhang Yong‐Kang
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Analgesic Activity of Some Side‐Chain Modified Anpirtoline Derivatives.
Authors: Radl Stanislav , Hezky Petr , Proska Jan , Hejnova Lucie , Krejci Ivan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Suppression of Ethyl Migration in the Synthesis of 2,5‐Anhydro‐1‐amino‐1,4‐dideoxy‐3‐thio‐D‐threo‐pentitol Hydrochloride, a Key Intermediate for Oral THF 1β‐Methylcarbapenems.
Authors: Bitha Panayota , Strohmeyer Timothy W. , Li Zhong , Lin Yang‐I
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: XAFS Spectroscopy of Organometallic Species and Clusters
Authors: Slovokhotov Yuri L.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Polycyclic Azines Derived from Pyrazolo[3,4‐b]pyridine.
Authors: El‐Emary T. I. , Hussein A. M. , El‐Kashef H. S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Coordination Among Se and Te Fluorides
Authors: Seppelt Konrad
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Continuous and Clean One‐Step Synthesis of Nano‐Particulate Ce1‐xZrxO2 Solid Solutions in Near‐Critical Water.
Authors: Cabanas Albertina , Darr Jawwad A. , Lester Edward , Poliakoff Martyn
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diels—Alder Reactions of Masked p‐Benzoquinones.
Authors: de March Pedro , Figueredo Marta , Font Josep , Rodriguez Sonia
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metal Catalysis Involving Cleavages of σ‐Bonds Between Group 14 Elements and Characterization of Metal Complexes Relevant to the Catalyst Intermediates
Authors: Tsuji Yasushi , Obora Yasushi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Synthetic Reactions Using Group 11 Metal Compounds as a Catalyst
Authors: Ito Hajime , Hosomi Akira
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phosphinooxazolines — A New Class of Versatile, Modular P,N‐Ligands for Asymmetric Catalysis
Authors: Helmchen Guenter , Pfaltz Andreas
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Aqueous Trimethylamine‐Mediated Baylis—Hillman Reaction.
Authors: Basavaiah Deevi , Krishnamacharyulu Marimganti , Jaganmohan Rao Anumolu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Endothelin Receptor Binding Activity of Synthetic Analogues of RES‐1149‐2.
Authors: Kraus George A. , Wang Xuemei
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The structure of native G‐actin
Authors: Wang Hui , Robinson Robert C. , Burtnick Leslie D.
Published: June 2010

Heat shock proteins act as cytoplasmic chaperones to ensure correct protein folding and prevent protein aggregation. The presence of stoichiometric amounts of one such heat shock protein, Hsp27, in supersaturated solutions of unmodified G‐actin leads to crystallization, in preference to polymerization, of the actin. Hsp27 is not evident in the resulting crystal structure. Thus, for the first time, we present the structure of G‐actin in a form that is devoid of polymerization‐deterring chemical modifications or binding partners, either of which may alter its conformation. The structure contains a calcium ion and ATP within a closed nucleotide‐binding cleft, and the D‐loop is disordered. This native G‐actin structure invites comparison with the current F‐actin model in order to understand the structural implications for actin polymerization. In particular, this analysis suggests a mechanism by which the bound cation coordinates conformational change and ATP‐hydrolysis. © 2010 Wiley‐Liss, Inc.
Control of cortical rigidity by the cytoskeleton: Emerging roles for septins
Authors: Gilden Julia , Krummel Matthew F.
Published: June 2010

The cortex is the outermost region of the cell, comprising all of the elements from the plasma membrane to the cortical actin cytoskeleton that cooperate to maintain the cell's shape and topology. In eukaryotes without cell walls, this cortex governs the contact between their plasma membranes and the environment and thereby influences cell shape, motility, and signaling. It is therefore of considerable interest to understand how cells control their cortices, both globally and with respect to small subdomains. Here we review the current understanding of this control, including the regulation of cell shape by balances of outward hydrostatic pressure and cortical tension. The actomyosin cytoskeleton is the canonical regulator of cortical rigidity and indeed many would consider the cortex to comprise the actin cortex nearly exclusively. However, this actomyosin array is intimately linked to the membrane, for example via ERM and PIP2 proteins. Additionally, the lipid membrane likely undergoes rigidification by other players, such as Bin‐Amphiphysin‐Rvs proteins. Recent data also indicates that the septin cytoskeleton may play a formidable and more direct role in stabilization of membranes, particularly in contexts where cells receive limited external stabilization from their environments. Here, we review how septins may play this role, drawing on their physical form, their ability to directly bind and modify membranes and actomyosin, and their interactions with vesicular machinery. Deficiencies and alterations in the nature of the septin cytoskeleton may thus be relevant in multiple disease settings. © 2010 Wiley‐Liss, Inc.
Modelling Inhalational Anaesthetics Using Bayesian Feature Selection and QSAR Modelling Methods
Authors: Manallack David T. , Burden Frank R. , Winkler David A.
Published: June 2010

The development of robust and predictive QSAR models is highly dependent on the use of molecular descriptors that contain information relevant to the property being modelled. Selection of these relevant features from a large pool of possibilities is difficult to achieve effectively. Modern Bayesian methods provide substantial advantages over conventional feature selection methods for feature selection and QSAR modelling. We illustrate the importance of descriptor choice and the beneficial properties of Bayesian methods to select context‐dependent relevant descriptors and build robust QSAR models, using data on anaesthetics. Our results show the effectiveness of Bayesian feature selection methods in choosing the best descriptors when these are mixed with less informative descriptors. They also demonstrate the efficacy of the Abraham descriptors and identify deficiencies in ParaSurf descriptors for modelling anaesthetic action.
Synthesis and Evaluation of Bis‐Thiazolium Salts as Potential Antimalarial Drugs
Authors: Caldarelli Sergio A. , Duckert Jean‐Frédéric , Wein Sharon , Calas Michèle , Périgaud Christian , Vial Henri , Peyrottes Suzanne
Published: June 2010

An innovative therapeutic approach based on the use of dicationic derivatives was previously designed to inhibit the biosynthesis of phosphatidylcholine in Plasmodium spp. Among these, bis‐thiazolium salts were shown to block proliferation of the malaria parasite at concentrations in the low nanomolar range. However, due to unsuitable molecular properties such as the presence of the two polar heads and flexibility in the linker, these compounds have low oral bioavailability. To characterize the structural requirements of the linker that lead to more rigid analogues with fewer rotatable bonds but which retain antimalarial activity, a new series of compounds incorporating an aryl moiety and eventually oxygen atoms were prepared, and their biological activity was evaluated. Structure–activity relationships suggest that the optimal linker construct is an aromatic group with two n‐butyl chains branched at the para position; two new leads (compounds 39 and 40) were selected for further development.
Discovery of a Class of Diketopiperazines as Antiprion Compounds
Authors: Bolognesi Maria Laura , Ai Tran Hoang Ngoc , Staderini Matteo , Monaco Alessandra , López‐Cobeñas Alberto , Bongarzone Salvatore , Biarnés Xevi , López‐Alvarado Pilar , Cabezas Nieves , Caramelli Maria , Carloni Paolo , Menéndez J. Carlos , Legname Giuseppe
Published: June 2010

Prion diseases are fatal neurodegenerative and infectious disorders for which effective pharmacological tools are not yet available. This unmet challenge and the recently proposed interplay between prion diseases and Alzheimer's have led to a more urgent demand for new antiprion agents. Herein, we report the identification of a novel bifunctional diketopiperazine (DKP) derivative 1 d, which exhibits activity in the low micromolar range against prion replication in ScGT1 cells, while showing low cytotoxicity. Supported by properly addressed molecular modeling studies, we hypothesized that a planar conformation is the major determinant for activity in this class of compounds. Moreover, studies aimed at assessing the mechanism‐of‐action at the molecular level showed that 1 d might interact directly with recombinant prion protein (recPrP) to prevent its conversion to the pathogenic misfolded prion protein (PrPSc)‐like form. This investigation suggests that DKP based antiprion compounds can serve as a promising lead scaffold in developing new drugs to combat prion diseases.
Occupational functioning, sickness absence and medication utilization before and after cognitive–behaviour therapy for generalized anxiety disorders
Authors: Linden Michael , Zubrägel Doris , Bär Thomas
Published: June 2010

Background: Cognitive–behaviour therapy (CBT) is efficacious in reducing symptoms of generalized anxiety disorders (GAD). The question is whether it is also efficient, i.e., whether there are also enduring effects with respect to improving utilization of medication and psychotherapy, or occupational functioning and sick leave after the end of treatment.

Method: The study was based on 44 outpatients (age 18–65 years; HAM‐A score ≥18; GAD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria as assessed by standardized interview) who were treated with 25 sessions of CBT (treatment by 12 state‐licensed behaviour therapists in office‐based practice; no psychotropic treatment for the duration of the therapy). The rate of medication treatment, occupational functioning and sick leave was assessed for 8 months before and after the end of treatment.

Results: In the comparison of the pre‐treatment and post‐treatment periods, 46.5% versus 7.2% of patients used psychotropic medication for at least 4 weeks and had been 3.1 versus 1.1 days on sickness absence per month, respectively. About 70% of patients showed impairment in occupational role performance during the pre‐treatment phase compared with 5% to 20%, depending on the dimension, in the follow‐up period.

Conclusions: The data suggest that CBT is not only efficacious in terms of symptom reduction but also efficient in terms of reducing inappropriate medication intake and improving occupational functioning. Copyright © 2010 John Wiley & Sons, Ltd.

Key Practitioner Message:

• Effects of any treatment should not only pertain to the present symptomatology but also to illness behaviour and occupational and social participation.

• When patients with GAD are treated with CBT, a reduction in sickness absence and an improvement of occupational functioning can be observed in the post‐treatment period.

• After CBT, a reduction of inappropriate medication can be seen.

• The data suggest that CBT in GAD patients reduces not only illness symptoms but also improves illness behaviour and role adjustment.
Modelling human movement in cholera spreading along fluvial systems
Authors: Righetto L. , Bertuzzo E. , Casagrandi R. , Gatto M. , Rodriguez‐Iturbe I. , Rinaldo A.
Published: June 2010

We propose an important extension of a previously studied, spatially explicit and hydrology‐driven, model of cholera spreading. Our reformulation concerns the role of different modelizations of human movement on the overall dynamics of the epidemics, which were previously expressed synthetically by bacterial diffusion. The system is composed of three compartments: susceptible and infected components, Vibrio cholerae dispersion and reaction dynamics. The underlying spatial framework is based on a reaction‐diffusion scheme, which is applied, for simplicity, to ecological corridors modelled as one‐dimensional lattices mimicking river reaches. In this geometry, we are able to predict important features of disease propagation, like the analytical evaluation of the spreading celerity of travelling fronts of epidemics. The explicit mechanism of human movement presented here leads to a comparison with previous approaches, revealing notable differences in how cholera spreads in space and time along the system. Studying human movement allows the analysis of specific quantities useful to policy makers and epidemiologists, such as the value of human diffusion which can generate upstream propagation of the disease. A robust relationship among key parameters, which links together diffusion mechanism, drift speed and resulting epidemic intensity, is also shown. Copyright © 2010 John Wiley & Sons, Ltd.
TGF‐β interactions with IL‐1 family members trigger IL‐4‐independent IL‐9 production by mouse CD4+ T cells
Authors: Uyttenhove Catherine , Brombacher Frank , Van Snick Jacques
Published: June 2010

TGF‐β and IL‐4 were recently shown to selectively upregulate IL‐9 production by naïve CD4+ T cells. We report here that TGF‐β interactions with IL‐1α, IL‐1β, IL‐18, and IL‐33 have equivalent IL‐9‐stimulating activities that function even in IL‐4‐deficient animals. This was observed after in vitro antigenic stimulation of immunized or unprimed mice and after polyclonal T‐cell activation. Based on intracellular IL‐9 staining, all IL‐9‐producing cells were CD4+ and 80–90% had proliferated, as indicated by reduced CFSE staining. In contrast to IL‐9, IL‐13 and IL‐17 were strongly stimulated by IL‐1 and either inhibited (IL‐13) or were unaffected (IL‐17) by addition of TGF‐β. IL‐9 and IL‐17 production also differed in their dependence on IL‐2 and regulation by IL‐1/IL‐23. As IL‐9 levels were much lower in Th2 and Th17 cultures, our results identify TGF‐β/IL‐1 and TGF‐β/IL‐4 as the main control points of IL‐9 synthesis.
Transition‐Metal‐Rich Borides – Fascinating Crystal Structures and Magnetic Properties
Authors: Fokwa Boniface P. T.
Published: June 2010

The ability to design and predict new phases in solid‐state chemistry remains a challenge. However, experiment and theory have been working together in the last decade to find new phases with targeted magnetic properties in the family of transition‐metal‐rich borides. These studies were very successful for boride phases crystallizing with the Ti3Co5B2structure type. Furthermore, strong variations of the magnetic properties in some series of compounds as a function of the number of valence electrons were observed experimentally and explained by using density functional theory calculations. The Zn11Rh18B8and Th7Fe3structure types have also produced many magnetically ordered phases, whereas the new Ti1.6Os1.4RuB2and Ti1+xRh2–x+yIr3–yB2structure types have the potential to produce new materials with interesting magnetic properties. The large family of perovskite boride phases has welcomed new members whose structures enable the ordering of boron atoms and vacancies. Renewed interest has been observed for boride phases crystallizing with the Cr23C6‐type structure, whose magnetic properties were mainly studied before the nineties.
1,2‐Oxazines as Building Blocks for Stereoselective Synthesis: Preparation of Oxygen‐Substituted 1,2‐Oxazines, either by Alcohol Addition or by Epoxidation, and Subsequent Hydrogenation Leading to 1,2‐Amino Alcohols and Pyrrolidines
Authors: Zimmer Reinhold , Buchholz Monika , Collas Markus , Angermann Jörg , Homann Kai , Reissig Hans‐Ulrich
Published: June 2010

Stereodefined oxygen‐substituted 1,2‐oxazines were prepared by three different routes. The cycloaddition of enol ethers such as 1 with α‐nitrosoalkenes generated in situ gave the heterocycles 3 and 4. Acid‐catalysed additions of alcohols to the 6H‐1,2‐oxazines 5 led to mixtures of the adducts 6 and the substitution products 7 with moderate chemoselectivity. Epoxidation of the 6H‐1,2‐oxazines 5 proceeded more efficiently and furnished the corresponding epoxides 25 and 32 in reasonable to excellent yields. It was demonstrated that the resulting oxygen‐substituted 1,2‐oxazines were suitable precursors for the preparation of cyclic or acyclic primary and secondary amines in racemic or enantiopure form. Hydrogenation of the 3‐phenyl‐substituted 1,2‐oxazines 3 and 25a and of (6S)‐ and (6R)‐32 preferentially furnished the 1,2‐amino alcohols 15, rac‐29 and (2S)‐ and (2R)‐29. On the other hand, reduction of the 3‐ethoxycarbonyl‐substituted 1,2‐oxazines 4, 6d and 20 led to the formation of the N‐protected proline esters 21–24 in moderate yields. It was also found that the 5‐methyl‐6H‐1,2‐oxazine 10 was a good precursor for the propargylic ether 11, which allowed a Pauson–Khand reaction leading to the tricyclic compounds 13 and 14. Hydrogen peroxide converted 10 into a hydroperoxide intermediate, which was further transformed into the 1,2‐oxazin‐6‐one 28b. Overall, the results demonstrate the remarkable potential of suitably substituted 1,2‐oxazine derivatives for the stereoselective synthesis of amines.