bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovaciones tecnológicas en odontología
Authors: Vázquez-Vázquez Febe Carolina
Published: May 2023

La era digital o era de la información comenzó a mediados de 1970 y a partir de entonces el ritmo de la tecnología ha aumentado de forma acelerada, esto ha revolucionado la forma en que nos comunicamos, interaccionamos, vivimos y trabajamos. La tecnología tiene un impacto importante en la odontología y traerá cambios sustanciales en la docencia, investigación y atención de los pacientes. Entre los cambios en los métodos de enseñanza se encuentran las innovaciones en la simulación clínica y el aprendizaje virtual, que poco a poco han ido sustituyendo el uso de imágenes 2D, disponibles en libros de texto, por modelos 3D, específicamente en el estudio de la anatomía humana, ya que son capaces de recrear de manera fidedigna los detalles anatómicos de los huesos, por lo que la utilidad de estos modelos es realmente valiosa en el estudio práctico de la anatomía.1
Análisis LIBS de la limpieza realizada por un láser Nd:Yag sobre instrumentos de níquel titanio usados
Authors: Vite Hernández Damara Citlali , Luna Domínguez Jorge Humberto , Luna Lara Carlos Alberto , Oliver Parra Rogelio
Published: May 2023

Introducción: los instrumentos endodóncicos usados retienen debris dentinario, lo que representa un riesgo biológico que afecta su esterilización. Objetivo: evaluar con la técnica de espectroscopia de plasmas inducida por láser (LIBS) la limpieza de instrumentos endodóncicos de NiTi tratados con láser Nd:Yag. Material y métodos: se evaluaron instrumentos ProTaper Next X2 (Dentsply Maillefer®, Ballaigues, Switzerland) y WaveOne Gold Primary (Dentsply Maillefer®, Ballaigues, Switzerland) bajo microscopio estereoscópi- co (20X) en dos etapas: 1) instrumentos usados, 2) instrumentos limpiados con ultrasonido o con láser Nd:Yag. En ambas etapas se registró la presencia y extensión de debris dentinario teñido con so- lución Van Gieson. Posteriormente, se analizó con técnica LIBS los elementos contenidos en el debris dentinario en instrumentos NiTi usados y tratados con diferentes métodos de limpieza. Resultados: la técnica láser Nd:Yag presentó mayor capacidad de limpieza (p < 0.0001). El análisis LIBS no mostró espectros de elementos conte- nidos en el debris biológico en los instrumentos tratados con ambos métodos. Conclusiones: el láser Nd:Yag es un método eficaz para la limpieza de instrumentos NiTi que elimina de su superficie los elementos contenidos en el debris dentinario.
Fuerza microtensil y aspecto superficial de una resina nanocerámica CAD/CAM tratada con diferentes métodos de grabado
Authors: Ibarra Azhela Del Ángel , Oliver Parra Rogelio , Luna Lara Carlos Alberto , Téllez Jiménez Héctor , Luna García Bertha , Luna Domínguez Jorge Humberto
Published: May 2023

Introducción: los materiales cerámicos infiltrados con polímero CAD/CAM necesitan tratamientos micromecánicos y químicos que modifiquen su superficie y favorezcan la adhesión a dentina de restauraciones indirectas. Objetivo: evaluar in vitro la fuerza microtensil que causa la combinación del tratamiento superficial de microarenado (MA), más ácido fluorhídrico (HF 10%), al aplicar un adhesivo universal (AU) sobre especímenes de Lava™ Ultimate (LVU). Material y métodos: se utilizó una nanocerámica de resina LVU (3M ESPE, St. Paul, MN, USA). Las muestras se dividieron en cuatro grupos. Grupo 1: control (sin tratamiento). Grupo 2: MA con Al2O3 de 50 μm (Zeta Sand Zhermarck Dental SpA, Italia) + AU (All-Bond Universal® Bisco Inc. Schaumburg, IL). Grupo 3: grabado con AF al 10% Angelus® (Solucoes Odontologicas, Londrina, Brazil) + AU. Grupo 4: MA +AF + AU. Los especímenes se cementaron con resina dual Duo-Link™ (Bisco Inc. Schaumburg, IL) en dentina media de terceros molares extraídos. Después de 24 horas se realizó la prueba de microtracción. El modo de fallo de las muestras se registró bajo estereomicroscopio a 20X. La rugosidad y aspecto superficial se evaluaron con microscopio electrónico de barrido (MEB) y microscopio de fuerza atómica (MFA). Resultados: el tratamiento de superficie de LVU con MA + AF + AU mostró diferencias significativas en la resistencia microtraccional (p < 0.011). El modo de fallo predominante en los grupos fue adhesivo. Se identificó una correlación significativa, al observar que a mayor rugosidad de la superficie tratada, había mayor resistencia microtraccional (r = 0.88) Conclusiones: la resina nanocerámica LVU grabada con MA y con AF crea una rugosidad superficial que combinada con un AU incrementa la resistencia de fuerza adhesiva en dentina.
Aproximaciones a la biblioclastia en México: siglos XX-XXI
Authors: Ruiz Corona Víctor
Published: May 2023

El objetivo del artículo es identificar algunas de las manifestaciones biblioclastas ocurridas en México durante el siglo veinte, a partir de una consideración de la biblioclastia como toda práctica que represente una afectación tanto al libro como a cualquier otro bien documental. La metodología empleada fue la investigación bibliográfica-hemerográfica, teniendo como principales resultados que en México, durante el periodo estudiado, hubo una serie de prácticas biblioclastas de diversa índole, como la destrucción física, el robo, la mutilación, el olvido y la desvalorización, que, en su conjunto, representó una afectación no sólo a los libros y a los documentos, sino al ecosistema que los rodea. En este sentido, se pudo determinar que el principal tipo de biblioclastia ocurrido en México durante el siglo veinte fue la biblioclastia por incuria, originada por la negligencia, así como la consideración de la biblioclastia más allá de la mera destrucción física del libro por motivos políticos, ideológicos o religiosos.
IoT based Smart Book Reader for Visually Impaired
Authors: Kale Shubham , Kumbhar Basavaraj , Patil Hitesh , Jaitpal Karan , Sinha Dr. Swati
Published: May 2023

Abstract: This paper presents an IoT- based smart book reader for visually impaired individuals, using a Raspberry Pi computer and various software tools. The system allows users to capture images of printed material using a camera, which are then processed using Tesseract OCR software to extract text. The extracted text is then translated from English to Marathi using the Google Cloud Translation API, and converted to speech using the Google Text-to-Speech API. The system is designed to be operated using a single hardware button, making it easy and intuitive for users with visual impairments. The proposed system offers a low-cost and portable solution for visually impaired individuals to access printed material, and has the potential to improve their quality of life.
Vision Controlled Motorised Wheelchair
Authors: E Rifath Ahamed , R Muthukrishnan , S Karthik , G Vijayakumar , A Salman Haris , M Vinoth Kumar
Published: May 2023

Abstract: Even in this modern day, it is very difficult for physically challenged people to move from one place to other without others help. To give them an independent feel, a smart eye-controlled system is provided. A novel design of an embedded cardiorespiratory monitoring system for wheelchair users is proposed. This system gets the input from eye. An eye-ball controlled wheelchair is a type of assistive technology designed for individuals with paralysis or limited mobility. The wheelchair is controlled through the movement of the user's eyes, allowing them to navigate the chair without the use of their hands or arms. The system consists of a set of sensors that detect eye movements, a microcontroller that interprets the signals, and a motor controller that translates the signals into movement. The user wears a headset with a camera that tracks the movement of their eyes, which is then relayed to the sensors. The wheelchair can be programmed to respond to different eye movements, such as blinking or sustained gaze in a particular direction. The system is designed to be intuitive and easy to use, with minimal training required. One of the primary benefits of the eye-ball controlled wheelchair is increased independence for individuals with limited mobility. It allows them to move around their environment and interact with others without needing assistance. Additionally, the system is non-invasive and does not require surgery or implants. The movement of the wheel chair will be controlled by these inputs. Depending on this input the wheel chair will move forward, left, right or backward. With the help of this system the user can move independently without others help. It also included with obstacle detection system to ensure the safety for the user. If any obstacle is detected then the indication can be given with the help of LCD.The entire system is composed of a sensor node, and a cloud server. The former is used to obtain continuous vitalsign signals, and the latter processes the sampled signals to estimate the temperature level, implemented in an embedded system to achieve a fully integrated radar system. MATLAB image processing is used to sense the movement of the eye ball’s direction using eye ball sensor (Straight Command, Left/Right Command, Stop Command). The system is cost effective and thus can be used by patients spread over a large economy range
Student Record Management System using Django
Authors: Patil Vivek K. , Patil Dhanashri S. , Satpute Harshada B. , Tayade Shubhangi N.
Published: May 2023

Abstract: Student Record Management System is a software helpful for students as well as department staff. The Student Record Management System (SRMS) is a web-based application designed to manage student records efficiently. Using the Django framework, SRMS includes features such as registration, enrolments, grading, photos, remarks, and record tracking The system focuses on student-related data, including their CGPA, address, phone number, fees, and other details. Administrators and faculty can access this information quickly and efficiently, reducing the time and effort required to manage student records. In addition to the SRMS, the project also includes a department website. The website is designed to provide information about the department, its facilities, and its programs. It includes a news section, an events section, a gallery section, and resources for students such as course materials and other important data. The website is also integrated with the SRMS, allowing students to access their personal records, view their grades and communicate with faculty and administrators. The website's responsive design enables students to access the website from any device, including smartphones and tablets. Overall, the SRMS and the department website provide a comprehensive solution for managing student records and improving the academic experience for students. The project's use of Django framework and responsive design make it a scalable and reliable solution for any educational institution. Moreover, the website's integration with the SRMS allows for a seamless user experience, reducing the time and effort required for administrative tasks. This can free up resources and enable faculty and administrators to focus on more strategic initiatives to enhance the quality of education and support for students
A Research Paper on Manual Design and Modelling of Box Culvert
Authors: Choudhary Shaista , Singh Akshay , Sharma Umakant
Published: May 2023

Abstract: Box culverts are the structures which are used when the path of water in the natural stream crosses roads, railway lines, flyovers etc. They are normally cheaper than bridges, which make them the natural stream passes through channels. In this work, the review of various authors and their views in the design and analysis of box culvert with software approach and comparison between software and manual approach has shown. The IS standard requirements in the design manual for roads and bridges (IRC-6-2000, IS 21-2000) is used in the structural designing of concrete box culverts. In this paper study about the different classes of IRC loadings and their effect on without and with cushioning conditions imposed on box culvert. The pressure cases are then checked for both with cushioning and without cushioning loading cases. The structure designing includes the considerations of pressure cases (Box empty, Full, surcharge load) and factors such as Impact load, Braking force, Dispersal of load through fill, Effective width, Coefficients of earth pressure, Live load etc. The structural elements are designed to withstand the maximum bending moments and shear forces respectively. In the present study, this paper provides full discussion on the provisions in the codes, considerations and justifications of all the above aspects of design.
Solar Agricultural Sprayer Robot
Authors: M Ravikumar H , L Thejaswini Bai M , B Vinayaka , B Lalitha , H Usama
Published: May 2023

Abstract: Manual spraying of pesticides and herbicides to crops and weed inhibitors onto the field are quite laborious work to humans. Manual trimming of selected unwanted plants or harvested crops from the field is also difficult. Our project proposes a multipurpose solar powered, flexible, Remote Controlled, semi-automated spraying robot with 4 Degrees of Freedom (DoF) in spatial movement, with an additional plant mowing equipment. The robot is designed to spray pesticide/insecticide directly onto individual lesions minimizing wastage or excess chemical spraying, hence making the system cost effective and also environment friendly. It is designed to cut down undesired plants selectively by remotely controlling the start and stop of the mowing system. Alternatively, it also serves the purpose of maintaining lawns and sports field made of grass. The same system can be used for water spraying and mowing the grass to desired levels, leading to proper maintenance of the field. The robot is designed to move at 1.4m/s, with an effective spraying area of 0.98 sq. m. by the nozzle and an effective cutting area of 0.3 sq. m. by the mower, when stationary. The prototype has a battery back-up of 7.2hrs under minimum load conditions.
La protección de los animales a la luz del derecho: ¿tienen derechos los animales?
Authors: Maruri Armand-Ugon Sofia , Montero Susalla Adriana
Published: May 2023

¿Es posible afirmar que los animales tienen dignidad?, ¿se puede hablar de derechos de especies no humanas?, ¿qué eco está teniendo esta teoría en Uruguay y en el mundo?, ¿qué implicancias jurídicas podría tener el reconocimiento de teorías de este tipo? A estas preguntas pretende responder este trabajo de investigación, a efecto de reivindicar el concepto de derechos humanos únicamente atribuible a los individuos de la especie humana; pero no por ello en contradicción con la necesidad de brindar protección a otras especies. En este artículo se estudia el estatuto jurídico de los animales, cómo se da la protección de las especies no humanas en el derecho comparado y en el derecho uruguayo, y cuáles son los desafíos pendientes en la materia y las cuestiones a mejorar que requieren atención por parte de las autoridades competentes.
Clinical and laboratory features and prognostic factors for outcome of progressive multifocal leukoencephalopathy in HIV-infected patients
Authors: Pokrovskaya A. V. , Samotolkina E. A. , Matosova S. V. , Kireev D. E. , Domonova E. A. , Voznesenskiy S. L. , Ermak T. N. , Samotolkina E. S. , Parkhomenko Yu. G. , Tishkevich O. A.
Published: May 2023

Objective: To analyze clinical and laboratory features to predict the outcome of progressive multifocal leukoencephalopathy (PML) in HIV-infected patients.

Materials and methods: Retrospective analysis of medical histories of HIV-infected patients with CNS lesions in 2015–2017, and dynamic monitoring of HIV patients with CNS lesions in 2018–2019, who were intensive care unit (ICU) in Infectious Clinical Hospital No. 2 of the Department of Health of Moscow.

Results and discussion: A total 196 patients with encephalitis/meningoencephalitis: 124 (63%) patients with detected JCPyV in the cerebrospinal fluid (CSF) — study group (JCPyV+), 72 patients with undetectable JCPyV in CSF — comparison group (JCPyV–). Late terms of hospitalization were noted, mainly in the JCPyV+ group (mean — 58±6 days). The majority of patients had severe immunodeficiency, in the JCPyV+ group the number of patients with CD4<200 cells/μl was significantly higher than in the JCPyV– group (87.8% and 75.8%, p<0.05). Only 22% of patients received antiretroviral therapy (ART) prior to hospitalization. The main clinical manifestations of PML in the study were: paralysis and paresis of the limbs, speech impairment, cognitive disorders in combination with cerebral symptoms in the absence of meningeal signs. In 87.8% patients with positive JCPyV DNA no other pathogens were detected in the CSF; in the patients without PML the detection of infectious agents in the CSF was also rare (14.3%). The disease led to the death for 78% patients in the JCPyV+ group and 72% JCPyV– group, p>0.05. The chance of survival was 2.5 times higher for patients admitted to hospital less than 14 days after deterioration (OR=2.468 [95% CI: 1.244–4.898]). Patients with CD4<200 cells/μL were 5.5 times more chance to die than patients with higher CD4 rates (OR=5.449 [95% CI: 2.388–12.431]). There was no relationship between the concentration of JCPyV DNA and HIV RNA in the CSF and their impact for the disease outcome.

Conclusion: Survival prognosis for PML during treatment in ICU was worser for patients hospitalized after 14 days from the onset of symptoms and with CD4<200 cells/μL. Early ART initiation for all HIV-positive individuals significantly reduces the number of opportunistic infections and improve life expectancy.
Prevalence of Adverse Health Effects of Tobacco Addiction in Different Types of Prakriti – An Observational Study
Authors: Jagdish Mandhane Rajat , Sawarkar Dr. Gaurav , Sawarkar Dr. Punam
Published: May 2023

According to the National Institute on Drug Abuse, tobacco is one of the most widely used addictive items in the United States (NIDA). Addiction is a long-term illness marked by obsessive drug seeking and usage and long-term chemical and molecular alterations in the brain. Tobacco smoking is linked to 5 million fatalities worldwide, making it one of the major causes of mortality. Comprehensive tobacco control programs can significantly lower the frequency of tobacco use. The study was a cross-sectional study. Approval was taken from the institutional ethical committee. Personal interviews were conducted at Mahatma Gandhi Ayurved College, Hospital & Research Centre, Salod (H), Wardha district. All the subjects were personally interviewed based on the questionnaire. The survey elicited 209 replies, and based on the findings, the following observations were made. Individuals who were addicted to tobacco chewing in the Wardha district were included in the study. One hundred percent of participants completed the survey. The evaluation used a question-and-answer format, a typical Prakriti assessment, and tobacco addiction-related questions. The study gathered 209 replies from tobacco-dependent residents in the Wardha district, who were selected based on their comments and observations. Tobacco chewing percentage was more found in males (21%) than females (2.8%). Twenty-five percent were primarily Vata Prakriti, fifty-nine percent were Pitta Prakriti, and eighteen percent were Kapha Prakriti. Compared to Pitta and Kapha Prakriti people, Vata-dominant Prakriti people are more likely to experience the negative effects of tobacco addiction.
Analysis of Possibilities and Impediments for Poland's Transition to an Innovative Economy
Authors: Amorim Vanessa , Bernardes Óscar , Santos Bárbara , Lima Rua Orlando
Published: May 2023

This article examines the most significant sources of innovation funding available to Poland. It is also intended to address the barriers to becoming a more innovative economy faced by the country under study. As is widely accepted, innovation is a critical component of any country's economic development and competitiveness in today's world. However, there are countries in the European Union (EU) that, despite their overall development, have lower innovation rates than the European average.
BUSINESS ANALYTICS: AN EXPLANATORY REPORT ON THE EVOLUTION OF BUSINESS INTELLIGENT AS AN ADVANTAGE IN THE DECISION-MAKING PROCESS
Authors: Fontanillas Carlos Navarro , De Souza Ítalo Galdino , Leão Mauricio de Souza , Cosenza Harvey José Santos Ribeiro
Published: May 2023

Muito se tem falado na utilização de dados no apoio ao processo decisório, este presente artigo tem o intuito de explicar quais são as fases e premissas que uma organização deve observar desde a Inteligência de Negócios clássica baseada em fatos ocorridos no passado ou Business Intelligence (BI) até os recursos mais avançados de Business Analytics (BA) ou Análise de Negócios que possibilite a criação e análise de cenários futuros com o propósito de antecipar acontecimentos, melhorar o processo decisório e por seguinte possibilitar uma gestão mais eficaz. Visa identificar como as empresas podem tirar o máximo dos dados para que os líderes das organizações possam utilizá-los de forma eficaz para a tomada de decisão, evoluindo do BI para o BA com foco no processo decisório. O BA se torna essencial para que o processo de tomada de decisão baseado em dados mitigue o fator “suposição” e impacte diretamente na performance da organização. Quais são os passos e premissas necessárias para evoluir o BI que utiliza análises descritivas e diagnosticas para o BA através de análise preditiva, prescritiva e cognitiva? Pesquisa exploratória, bibliográfica e documental, será baseada em modelos de gestão e governança das organizações empresariais. Demonstrar como as organizações podem evoluir para um patamar que lhes permitam acompanhar, analisar tendências e predições impactando diretamente o processo decisório das organizações. O presente trabalho tem por objetivo oferecer um caminho para evolução do processo de tomada de decisão das organizações baseando-se em dados e mitigando a suposição no processo decisório.
Estrategia de permanencia estudiantil. Habitar la universidad
Authors: Urrego Romero John Edisson
Published: May 2023

ITM Académico da vida a una serie de publicaciones derivadas de la reflexión, la experiencia y los aprendizajes institucionales con el ánimo de ofrecer material ágil en sus posibilidades de comprensión y de fácil acceso, relacionado con políticas, lineamientos y reflexiones inherentes al quehacer pedagógico y académico cotidiano. Sus destinatarios, los docentes y el personal académico administrativo, además de todos aquellos actores comprometidos con la conquista de los propósitos inherentes a la formación integral de los estudiantes, encontrarán en estos recursos orientaciones altamente útiles, contextualizadas en los fundamentos y las estrategias para la acción del ITM, y en las realidades y tendencias de la educación superior en el país. Deseamos que este compendio, abierto a la actualización permanente, se constituya en pretexto para la mirada —en clave misional, institucional y pedagógica— a las disposiciones inherentes a los programas académicos y a las prácticas educativas y didácticas para impulsar el pensamiento y la decisión argumentada y legítima que debe caracterizar el hacer en la formación y, para ella, resignificar nuestras versiones de la docencia y así hacer cada vez mejor aquello que por vocación y por convicción nos convoca, y generar nuevos motivos para la pregunta, el diálogo, la innovación en pro de la transformación de los sujetos, sus realidades y sus contextos.
Competitive parity as strategic dimension – little to gain, much to lose
Authors: Richter Barbara , Hanf Jon H.
Published: May 2023

It is essential for firms in the agri-food business to ensure specific product attributes in the long run and to avoid reputational damage. Competitive advantages cannot be achieved with such product attributes; however, they must be ensured to remain competitive in the long run. Searching for literature on competitive parity resulted to be very difficult and literature on competitive parity seems to merely exist in strategic management literature. The question arises as to whether competitive parity is also a strategic dimension to which companies must pay attention in strategic management, especially with regard to the allocation of scarce resources. Since the majority of firms in the agri-food business work together in supply chain networks, another research question arises: is competitive parity also relevant at the network-level? To answer these questions a systematic literature review, which is based on deliberately chosen leading journals in the field of strategic management and chain management, is conducted. Results on the firm-level and the network-level show that there is hardly any literature on competitive parity available. This paper aims to contribute to a better theoretical understanding of competitive parity in strategic management. It develops a theoretical frame of chain management which combines the aspects of competitive parity with those of chain management in the agri-food business. From this, managerial implications for focal firms in the agri-food industry as well as implications for future research in this field should be derived.
Examining growth centers and agricultural base commodities to enhance regional development in Tanjung Jabung Barat Regency, Jambi Province
Authors: Achmad Erni , Zamzami Zamzami , Hariza Nurul , Suparta I Wayan , Dhora Sony Tian
Published: May 2023

Determining growth centers and agricultural base commodities is essential for optimizing economic development and achieving economic equality in the Tanjung Jabung Barat Regency area. This study aimed to identify sub-districts that could become growth centers, establish agricultural commodities based in each Tanjung Jabung Barat Regency sub-district, and examine interactions between growth centers and surrounding areas. Three methods employed in this research include Scalogram analysis, Centrality Index, Location Quotient, and Dynamic Location Quotient. Based on the Scalogram analysis and Centrality Index results for the 13 Tanjung Jabung Barat Regency sub-districts, four sub-districts were identified as potential growth centers: Tungkal Ilir, Tebing Tinggi, and Merlung. The Tanjung Jabung Barat Regency Government is recommended to establish basic commodity specialization in each sub-district and strengthen inter-regional linkages to accelerate regional economic equity.
Cultos de matriz africana: análise antirracista e decolonial sobre a imunidade tributária em Poções-BA
Authors: Sarno Antonio Leandro Fagundes , Oliveira de Carvalho Cláudio
Published: May 2023

Este artigo tem como objetivo refletir sobre o racismo institucional que é perpetuado na manutenção da cobrança do Imposto sobre a Propriedade Territorial Urbana (IPTU) aos terreiros no município de Poções, na Bahia, bem como sobre a necessidade da implementação de políticas públicas e de uma hermenêutica jurídica decolonial que valorizem a cultura afrodiaspórica. O estudo se ancorou à luz da Constituição Federal de 1988, trazendo destaque para a discussão do racismo dentro das políticas públicas, os conceitos de tributo e de imunidade tributária como um processo político e de decolonialidade. O percurso metodológico trilhou por uma abordagem qualitativa, de cunho bibliográfico, com base na legislação brasileira e em artigos científicos, dissertações e livros disponibilizados pela Internet. O recorte temporal corresponde aos dois últimos exercícios 2021 e 2022 para cobrança do IPTU dos imóveis urbanos do município de Poções. Por fim, considera-se que a insistente cobrança do IPTU em espaços de culto religioso de matriz africana, contrariando o cumprimento da Constituição federal de 1988 repercute os fortes resquícios patriarcais e racistas em que a sociedade brasileira ainda perpetua em suas práticas cotidianas.
O Direito à Saúde: uma análise com Comunidades Quilombolas baianas
Authors: Mussi Leila Maria Prates Teixeira , Oliveira Ilzver de Matos , Almeida Claudio Bispo de , Mussi Ricardo Franklin de Freitas
Published: May 2023

A concretização do direito à saúde deve ser viabilizada pelo Estado, com foco na efetivação das políticas públicas para garantia da implantação e funcionamento dos serviços demandados pelos respectivos grupos populacionais. Destarte, essa escrita objetivou analisar como o direito à saúde é contemplado em comunidades quilombolas de uma região geográfica baiana. Metodologicamente enquadra-se como de abordagem qualitativa, com informações obtidas por meio de entrevistas estruturadas (sobre a infraestrutura e/ou serviços públicos de saúde) desenvolvidas com as representações das Associações de Moradores de 14 quilombos da região geográfica de Guanambi/Bahia durante o ano de 2016. Os achados indicam que uma comunidade possuía estrutura física específica para atendimentos básicos em saúde, no entanto, estava desativada. Três comunidades não tinham cobertura do Programa de Agentes Comunitários de Saúde (PACS). Entre as 11 que indicaram cobertura do Programa, em sete as(os) profissionais não residiam no território do quilombo. Diante da ampla ausência de infraestrutura e recorrente inadequação na prestação de serviços do PACS, evidencia-se a permanente negligência ao direito à saúde nesta população quilombola.
MDCT and MRI in bronchiectasis in older children and young adults-A non-inferiority trial
Authors: Lokesh * , Jana Manisha , Naranje Priyanka , Bhalla Ashu , Kabra Sushil , Hadda Vijay , Gupta Arun Kumar
Published: May 2023

Purpose To compare and evaluate the usefulness of MRI with CT
as radiation free alternative To compare the reproducibility of CT and
MRI scores To compare MRI and CT scores with pulmonary function tests
(PFT) To evaluate the role of DWI in bronchiectasis. Methods In
this prospective study, 25 patients between 7-21 years of age with a
clinical/radiological diagnosis of bronchiectasis underwent MDCT (with
HRCT reconstruction) and MRI chest. MRI and CT scoring was performed
using modified Bhalla score -Helbich’s score by two independent
radiologists for all parameters. A final consensus score was recorded.
both in CT and MRI. The overall image quality of different MRI sequences
to identify the pathologies was also assessed. Appropriate statistical
tests were used for inter-observer agreements, and correlation amongst
CT and MRI; as well as CT, MRI and PFT. Results Strong
agreement (ICC 0.80-0.95) between CT and MRI was seen for extent and
severity of bronchiectasis, number of bullae, sacculation/abscess,
emphysema, collapse/ consolidation, mucus plugging, and mosaic
perfusion. Overall CT and MRI scores had perfect concordance (ICC
0.978). Statistically significant (p-value <0.01)
intraobserver and interobserver agreement for all CT and MRI score
parameters was seen. A strong negative correlation was seen between
total CT and MRI severity scores and FEV1, FVC, FEF 25-75%. DWI MR,
with an ADC cut-off of 1.62 x 10 mm
/sec had a sensitivity of 70% and specificity of
75% in detecting true mucus plugs. Conclusion MRI with DWI can
be considered in the diagnostic algorithm for assessment of lung changes
in bronchiectasis as a radiation-free non-invasive method of imaging in
children, especially in follow-up.
A hybrid approach for advanced monitoring and forecasting of fouling with application to an ethylene oxide plant
Authors: Sansana Joel , Rendall Ricardo , Castillo Ivan , Bruijne Luc de , Huggins Jonathan , Phillips Ailene , Reis Marco
Published: May 2023

Fouling in heat exchangers leads to increased pressure drop, associated
with higher energy consumption, utility costs, and CO$_2$ emissions.
However, other effects can also take place, threatening process
operations and safety. This is the case of ethylene oxide operations,
where unplanned outages and decomposition events pose significant safety
risks. Therefore, the development of a framework for advanced monitoring
and forecasting of heat exchanger fouling is both important and
opportune to improve the reliability and safety of the operation. We
propose a hybrid approach, where knowledge-based feature generation is
integrated with data-driven methods, to forecast a key performance
indicator (KPI) that acts as a fouling surrogate. The forecasting model
can predict one-month ahead with an accuracy of R$^2$ = 0.7. We
also show that long-term forecasting is possible with this model, which
can be applied to optimize maintenance scheduling. The solution can be
extended to other situations, where fouling takes place.
Orientia tsutsugamushi : A life between escapes
Authors: Fromm Lea , Mehl Jonas , Keller Christian
Published: May 2023

Intracellular bacteria have evolved different strategies to invade,
replicate and persist in, and eventually exit from their hosts. The life
cycle of the mite-borne, obligate intracellular pathogen Orientia
tsutsugamushi (Ot), the causative agent of human scrub typhus, differs
in many aspects from that of other members of the Rickettsiales order.
Particularly, the non-lytic cellular exit of individual Ot bacteria at
the plasma membrane closely resembles the budding of enveloped viruses,
but has only been rudimentarily studied at the molecular level. This
brief review is focused on the current state of knowledge of escape
events in the life cycle of Ot. Also, open research questions and novel
experimental approaches are proposed.
Infection remediation after septic device extractions - comparison of three treatment strategies including a one-year follow-up
Authors: Burger Heiko , Strauß Mona , Chung Da-Un , Richter Manfred , Ziegelhoeffer Tibor , Hakmi Samer , Choi Yeong-Hoon , Pecha Simon
Published: May 2023

Introduction: Treating patients with CIED infections is often
challenging. In general, the infected device, including all leads, needs
to be completely removed before a new CIED can be implanted. Especially
in pacemaker-dependent patients, it is often impossible to have a
device-free interval to treat the infection. In those cases, the
question remains when to implant a new CIED and which bridging strategy
to use. Methods: In this single-center retrospective analysis,
we included 190 patients who received a complete CIED system extraction
between 2013 and 2019 due to device-related infection. We compared three
different treatment algorithms. Group 1 (SR) included 89 patients who
received system removal only (and delayed re-implantation). Group 2 (EL)
consisted of 28 patients who were treated with lead extraction and
simultaneous epicardial lead implantation, while the 78 patients in
Group 3 (SI) received lead removal with simultaneous contralateral
implantation of a new device. We retrospectively analyzed the peri- and
postoperative course and one-year follow-up. Results: Patients
in the SR and EL groups were significantly older, had more comorbidities
and a higher percentage of systemic infection compared to the SI group.
We found a comparable high number of successful infection treatments in
all groups, with complete lead removal in 95.5%, 96.4%, and 93.2% for
the SR, EL, and SI groups, respectively. Lead vegetations were removed
in 97.7%, 94.1%, and 100%. Device re-implantation was 100% in the EL
and SI groups, whereas in the SR group, only 49.4% of patients received
a device re-implantation. At one-year follow-up, the percentage of
freedom from infection and pocket irritation was comparable between
groups (94.7% SR and EL, 100% SI). We observed no procedure-related
mortality, while one-year mortality was 3.4% in the SR, 21.4% in the
EL and 4.1% in the SI group. Conclusion: We found comparable
success rates regarding device removal, successful infection treatment
and perioperative course between groups. However, most likely due to the
sicker patient collective with a high number of systemic infections, the
one-year mortality was significantly higher in the EL group. Treatment
algorithm should be selected due to type, severity, location of
infection and comorbidities of the patients.
Acute Kidney Injury, Renal Impairment and Renal Failure Associated with Sodium Glucose Co-transporter-2 Inhibitors in At-Risk Groups: A Systematic Review
Authors: Ziser Kate , LIVORI Adam , Morton Jedidiah , Prosser Adaire , Ilomaki Jenni , Wood Stephen
Published: May 2023

Introduction Randomised controlled trials show a reduction in acute
kidney injury, renal impairment, and acute renal failure after
initiation of a sodium glucose cotransporter-2 inhibitor. Observational
literature on the association is conflicting, however important to
understand for populations with a higher risk of medication-related
adverse renal events. We aimed to systematically review the literature
to summarize the association between sodium glucose cotransporter-2
inhibitor use and acute kidney injury, renal impairment, and acute renal
failure in three at-risk groups: older people aged >65
years, people with heart failure, and people with reduced renal
function. Methods Data Sources: A systematic search of Embase
(1974–29/03/21) and PubMed (1946–29/03/21) was performed. Study
Selection: RCTs and observational studies were included if they reported
numbers of acute kidney injury or acute renal failure in people using
sodium glucose cotransporter-2 inhibitors, compared to other diabetic
therapies. Studies needed to report results by level of renal function,
heart failure status, or age. Results Of 858 results, 6 studies were
included. The absolute risk of acute kidney injury or acute renal
failure was higher in people >65 years compared to those
<65 years, higher in people with heart failure (vs. without),
and higher in people with reduced kidney function (vs. preserved kidney
function), but insufficient evidence to determine if the relative effect
of sodium glucose cotransporter-2 inhibitors on this risk was similar
for each group. Conclusion At risk cohorts are associated with a higher
incidence of acute kidney problems in users of sodium glucose
cotransporter-2 inhibitors.
Timing of critical isthmus from end of P wave and usefulness of activation mapping with window of interest from end to end of P wave in reentrant atrial tachycardias
Authors: Kwon Chang Hee , Choi Ji-Hoon
Published: May 2023

Introduction: In activation mapping of reentrant atrial
tachycardia (AT), there was no reference for window of interest (WOI).
We assumed that the critical isthmus will exhibit the slowest conduction
velocity, and thus, may be located in an isoelectric line after
prominent P wave . We examined the timing of a successful
termination site from end of the P wave and attempted to determine
whether the critical isthmus can be identified using activation mapping
when WOI was set as end to end of the P wave. Methods: Forty
patients with 54 reentrant ATs who underwent 3D electroanatomic mapping
and radiofrequency catheter ablation were evaluated retrospectively. The
critical isthmus was defined as a successful termination site. We
evaluate critical isthmus timing from end of the P wave and ratio of
critical isthmus timing from end of the P wave to tachycardia cycle
length. Results: In 54 reentrant ATs, macroreentry was
identified in 46 (85.2%) and microreentry was identified in eight
(14.8%). The timing of the critical isthmus site from end of the P wave
was -4.0 ± 31.1 msec (Macroreentry vs. Microreentry; -8.9 ± 29.4 msec
vs. 24.0 ± 26.7 msec; P = 0.005). The ratio of critical isthmus timing
from end of the P wave to tachycardia cycle length was -1.4 ± 10.5%
(Macroreentry vs. Microreentry; -3.1 ± 9.8% vs. 8.3 ± 9.3%, P = 0.004)
Conclusion: The critical isthmus of reentrant AT is located
within 10% backward and forward from end of the P wave to tachycardia
cycle length. Setting the WOI from end to end of the P wave is useful
for identification of the critical isthmus through activation mapping in
reentrant AT.
Dietary intake is associated with the prevalence of uterine leiomyoma in Korean women: A retrospective cohort study
Authors: Kim Sunmie , Kim Min-Jeong , Kim Jin Ju , Kim Young Sun , Song Ji Hyun , Lee Jung Eun , Youn Jiyoung , Yang Sun Young
Published: May 2023

Objective: To evaluate the association between dietary intake
and the prevalence of uterine leiomyoma (UL) in Korean women.
Design: A retrospective cross-sectional study with dietary
intake assessment. Setting: A Health check-up center
Population: A cohort of 672 Korean women aged 25–65 years from
a previous study. Methods: Dietary intake was assessed using
food frequency questionnaire (FFQ), and the presence of UL was evaluated
by ultrasonography. Multiple logistic regression models were used to
analyze the relationship between dietary intake and the prevalence of UL
with adjustment for confounding factors. Main Outcome Measures:
Dietary intake and prevalence of UL. Results: A total of 219
(32.6%) women were diagnosed with UL. High intakes of fish and poultry
were associated with a high prevalence of UL; ORs (95% CIs) comparing
top vs. bottom quartiles were 1.70 (1.02-2.84; p trend = 0.049) for fish
intake and 1.85 (1.09 -3.14; p trend = 0.07) for poultry intake. High
intake of dairy products was inversely associated with the prevalence of
UL (OR 0.59, 95% CI 0.36–0.98; p trend = 0.06). When we examined pre-
and post-menopausal women separately, the association for poultry intake
was generally limited to postmenopausal women. In premenopausal women,
those with higher vegetable intake had a lower prevalence of UL (OR
0.47, 95% CI 0.22 -1.01 for top vs. bottom quartiles; p trend = 0.01).
Conclusions: We found that high intakes of fish and poultry,
but low intake of dairy products, were associated with a higher
prevalence of UL. Vegetable intake was inversely associated with the
prevalence of UL in premenopausal women.
Comparative proteomic analysis of three major extracellular classes secreted from human adenocarcinoma and metastatic colorectal cancer cells: exosomes, microparticles and shed midbody remnants
Authors: Suwakulsiri Wittaya , Xu Rong , rai alin , Chen Maoshan , Shafiq Adnan , Greening David , Simpson Richard
Published: May 2023

Cell-derived extracellular vesicles (EVs) are evolutionary-conserved
secretory organelles that, based on their molecular composition, are
important intercellular signaling regulators. At least three classes of
circulating EVs are known based on mechanism of biogenesis: exosomes
(sEVs/Exos), microparticles (lEVs/MPs) and shed midbody remnants
(sMB-Rs). sEVs/Exos are of endosomal pathway origin, microparticles
(lEVs/MPs) from plasma membrane blebbing, and shed midbody remnants
(sMB-Rs) arise from symmetric cytokinetic abscission. Here, we isolate
sEVs/Exos, lEVs/MPs and sMB-Rs secreted from human isogenic primary
(SW480) and metastatic (SW620) colorectal cancer (CRC) cell lines in
milligram quantities for label-free MS/MS-based proteomic profiling.
Purified EVs revealed selective composition packaging of exosomal
protein markers in SW480/SW620-sEVs/Exos, metabolic enzymes in
SW480/SW620-lEVs/MPs, while centralspindlin complex proteins,
nucleoproteins, splicing factors, RNA granule proteins,
translation-initiation factors, and mitochondrial proteins selectively
traffic to SW480/SW620-sMB-Rs. Collectively, we identify 39 human
cancer-associated genes in EVs; 17 associated with SW480-EVs, 22 with
SW620-EVs. We highlight oncogenic receptors/transporters selectively
enriched in sEVs/Exos (EGFR/ FAS in SW480-Exos and MET, TGFBR2, ABCB1 in
SW620-sEVs/Exos). Interestingly, MDK, STAT1, and TGM2 are selectively
enriched in SW480-sMB-Rs, and ADAM15 to SW620-sMB-Rs. Our study reveals
sEVs/Exos, lEVs/MPs and sMB-Rs have distinct protein signatures that
open potential diagnostic avenues of distinct types of EVs for clinical
utility.
Analyzing the effectiveness of different testing techniques in ensuring software quality
Authors: Kumari K.T.C.R. , Silva D. I. De , Bandara R.M.P.C. , Dias S. M. D. T. H. , Weerasinghe M.L.L. , Hansika A.G.D.R.
Published: May 2023

Software testing is an essential process in software development
that aims to identify defects and ensure that software is functioning as
intended. Various testing techniques are employed to achieve this goal,
but the effectiveness of these techniques varies. In this research
paper, analyzes the effectiveness of different testing techniques in
ensuring software quality. The paper explores different testing
techniques, including manual and automated testing, and evaluate their
effectiveness in terms of identifying defects, reducing the number of
defects in software, and ensuring that software meets its functional and
non-functional requirements. Moreover, the paper will also investigate
the impact of factors such as testing time, test coverage, and testing
environment on the effectiveness of these techniques. This research aims
to provide valuable insights into the effectiveness of different testing
techniques, enabling software development teams to make informed
decisions about the testing approach that is best suited to their needs.
By improving testing techniques, the number of defects in software can
be reduced, enhancing the quality of software and ultimately providing
better software for users.
The effects of structural change on economic growth: A panel data analysis
Authors: Trofimov Ivan
Published: May 2023

This paper attempts to enhance empirical understanding of the effects of
structural-change variables on economic outcomes. The relationships between
sectoral shares and (1) the speed of structural change and (2) economic
growth were examined for a large panel of 111 economies over the period of
1971-2018. Given the time series properties of the series and the absence of
a long-run relationship between them, the panel OLS and VAR models were
employed. The results are largely in line with previous empirical research:
it was established that a lack of industrialisation effort (manifested in
the persistence of agriculture as a share of GDP) and ?servicisation? (the
expansion of the services share of GDP) negatively affect GDP growth rates.
In contrast, a growth in industry and manufacturing shares positively
influences economic growth, as does accelerated structural transformation
(represented by the respective index of structural change).
Managers’ Use of an Omission Strategy to Perpetrate Fraud and Auditors’ Evaluations of the Resulting Misstatements
Authors: Hamilton Erin L. , Smith Jason L.
Published: May 2023

In this article, we provide a practitioner summary of our paper “Error or Fraud? The Effect of Omissions on Management’s Fraud Strategies and Auditors’ Evaluations of Identified Misstatements” (Hamilton and Smith 2021). In that study, we investigated (1) whether managers employ an “omission strategy” to reduce the perceived intentionality of their fraudulent misstatements and (2) whether auditors are prone to believe that such omissions are unintentional. We found that managers choose to perpetrate fraud by omitting transactions from the financial statements and by omitting critical information from supporting documents, rather than using more active forms of fraud (e.g., providing false information). We also found that auditors are less skeptical of misstatements when they involve omission, as opposed to more active forms of misrepresentation. Overall, our study identifies a concerning pattern, wherein the method of fraud chosen by managers—omission—is unlikely to be judged as intentional by auditors.
Asymmetric Disclosure, Noise Trade, and Firm Valuation
Authors: Cianciaruso Davide , Marinovic Iván , Smith Kevin
Published: May 2023

We study the impact of asymmetric (i.e., conservative or aggressive) disclosure on a firm’s price in the classic setting in which its stock is traded by risk-averse investors and noise or liquidity traders. We show that asymmetric accounting policies alter the relative risk faced by investors when they short versus long, which causes market liquidity to differ for positive versus negative demand shocks. As a result, accounting conservatism raises firms’ valuations and lowers their expected returns. We further demonstrate that the relationship between accounting informativeness and expected returns depends upon the skewness of investors’ prior beliefs. Finally, we find that a firm that can commit to an accounting policy can tailor this policy to benefit from noise trade and foster overvaluation.

JEL Classifications: D72; D82; D83; G20; M41.