bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of a Combination of Caudal Levobupivacaine with Fentanyl and Levobupivacaine Alone for Alleviating Postoperative Pain During Infraumbilical Procedures in Children Under 3 Years
Authors: Vakkapatti Muralidar , Shenoy Thrivikram , Bhat Sonal
Published: November 2019

Background:

To compare the post-operative analgesic efficacy of caudal blockade using levobupivacaine alone and a combination of fentanyl with levobupivacaine in children under 3 years undergoing infraumbilical surgeries. Combination of levobupivacaine with fentanyl and levobupivacaine alone in children for caudal block was never studied before. Hence there was a need for the study.

Methods:

After approval from Institutional Ethical Committee, Kasturba Medical College, Mangaluru, 60 patients of age group 0-3 years, either sex of ASA physical status 1 and 2 undergoing infraumbilical surgeries were chosen after written parental consent and were randomised into 2 groups of 30 each L and LF using computer generated block randomisation to receive caudal blocks. Post operatively assessed for pain using CHIPPS scale at 2, 4, 6, 12 and 24 hours and compared in both groups.

Results:

Out of 60 patients, 30 in each group [L and LF], CHIPPS scores at 2, 4, 6, 12 and 24 hours post-operatively exhibited a p-value of 0.545, 0.492, 0.626, 0.166, and 0.329 respectively [not significant]. Mean duration of analgesia was 14.60 in Group L & 17.67 in Group LF with a t test p value of 0.119 [not significant].

Conclusion:

Combination of fentanyl with levobupivacaine when compared to levobupivacaine alone for caudal block was equianalgesic in children less than 3 years undergoing infra umbilical procedures.
The Mixture of Topical Anesthetic and Chlorhexidine at the Delivery Site in Microbial Reduction Efficiency
Authors: Srisatjaluk Ratchapin Laovanitch , Kaewjiaranai Thanawat , Wongsirichat Natthamet
Published: November 2019

Background:

Antimicrobial properties of some anesthetic agents have been reported which may be useful for infection control. Topical lidociane (10%) showed some extent of antimicrobial activity on oral microflora.

Objective:

This study aimed to determine whether the antimicrobial efficiency of topical lidocaine can be enhanced by adding chlorhexidine.

Methods:

The Lidocaine-Chlorhexidine (LD-CHX) preparation was prepared by mixing 2.0% CHX and 10% LD with various ratios. The anesthetic efficiency was tested on the oral mucosa of 26 volunteers by Pin Prick Test. Pain scores were recorded using the Numerical Rating Scale (NRS). Antimicrobial effects of 10% LD, 0.2% CHX, and LD-CHX preparations were evaluated.In vitrostudy was conducted against seven standard bacterial strains. Forin vivostudy, oral biofilms of 26 volunteers were collected by imprint technique using filter papers. Bacterial growth from the samples after applying the test solutions was compared to the control. Antimicrobial efficiency was expressed as microbial reduction scores from 4-0 (highest to lowest).

Results:

The LD-CHX preparations that had comparable anesthetic efficiency to 10% LD were those containing 9% and 8% LD. These LD-CHX preparations showed microbial reduction scores of 3 and 4 on seven bacterial strains and oral biofilms.

Conclusion:

This study showed the antimicrobial and anesthetic effectiveness of new lidocaine-chlorhexidine preparations bothin vitroandin vivo.We also confirmed the effectiveness of infection control protocol in oral surgery using CHX mouthwash prior to topical LD.
Evaluación multicriterio y multiobjetivo para optimizar la selección de áreas para establecer plantaciones forestales
Authors: Hernández-Zaragoza Pedro , Valdez-Lazalde José René , Aldrete Arnulfo , Martínez-Trinidad Tomás
Published: November 2019

La selección del sitio adecuado para establecer plantaciones forestales es crucial si se desea maximizar su probabilidad de éxito. Los análisis de aptitud de tierras sirven para ese propósito al empatar los requerimientos ecológicos de las especies a plantar con el potencial productivo del suelo y con las condiciones climáticas existentes para el crecimiento óptimo de las especies elegidas. Este estudio describe un modelo, desarrollado en el marco del proceso analítico jerárquico y la asignación de tierras multiobjetivo e integrado en un sistema de información geográfica, para seleccionar el sitio óptimo para el establecimiento de plantaciones forestales comerciales en los municipios Durango, Nombre de Dios y Súchil, del estado de Durango, México, considerando seis especies de pino (Pinus engelmannii, P. leiophylla, P. arizonica, P. cembroides, P.chihuahuana y P. durangensis). El modelo es jerárquico, considera criterios y subcriterios climáticos, edafológicos y topográficos que afectan la localización de áreas adecuadas para establecer plantaciones forestales comerciales. Los valores de los subcriterios fueron estandarizados, ponderados y ordenados mediante matrices de comparaciones pareadas, considerando su importancia para el desarrollo de plantaciones. El modelo inicialmente cuantificó la aptitud de la tierra para establecer plantaciones forestales. Posteriormente, los resultados de aptitud se optimizaron mediante un procedimiento multiobjetivo para identificar la mejor especie a plantar en la zona bajo cuatro escenarios de decisión: turno de producción, calidad de la madera, supervivencia y susceptibilidad a plagas y enfermedades. Los resultados indican que el municipio de Durango presenta la mayor cantidad de áreas óptimas para establecer plantaciones forestales con las especies analizadas.
The Influence of Job Demand, Respect, and Rapport on Work Engagement of Employees in the Foodservice Sector
Authors: Zakaria Zainuddin , Wan Nawang Wan Ramlah , Jusoh Zuraini , Kamaludin Mohamad Ariff
Published: November 2019

Many foodservice operators in Malaysia depend on superior services to entice customers to keep visiting their business. The researchers chose a purposive convenience sampling, and questionnaires were distributed to 303 employees in the foodservice industry in three selected districts in Terengganu, Malaysia. Results of the inferential analysis revealed that there are positive relationships between two of the independent variables, respects, and Rapport with the dependent variable, job engagement. Job demand, however, has no significant impact on Job Engagement. We proposed that trust, efficient communication, mutual respect, and the honest relationship has a strong impact on employees’ engagement with their job.Keywords: Job Engagement; Job Demand; Rapport; Foodservice Industry eISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i12.1933
О скорости термомиграции жидких цилиндрических включений в кристалле в стационарных тепловых условиях
Authors: Гармашов С.И.
Published: November 2019

Based on model ideas about the cross-sectional shape of a liquid cylindrical inclusion migrating through a crystal under the action of a temperature gradient in the case of the stationary thermal conditions, the dependences of the velocity and cross-sectional shape of the inclusion on its cross-sectional area have been calculated and analyzed for different values of the specific interfacial energy, the degree of its anisotropy, and the degree of difficulty of interface processes. The possibility of a nonmonotonic dependence of the velocity of the cylindrical inclusion on the area and thickness of its cross section has been shown.
Оптические свойства сферических металлических наночастиц, покрытых слоем оксида
Authors: Коротун А.В. , Коваль А.А.
Published: November 2019

In the work of the classical theory, the optical properties of an ensemble of metallic nanoparticles coated with an oxide layer are investigated. The influence of electron scattering mechanisms on the polarizability of nanoparticles is analyzed. The limiting case of a thin oxide layer is considered, for which analytical expressions are obtained for the real and imaginary parts of the polarizability. The evolution of the frequency dependences of the polarizability and extinction coefficient with varying particle size and oxide layer thickness is studied. It is shown that taking into account the size dependence of the surface component of the relaxation time leads to a change in the nature of the size dependence of the frequency of surface plasmons of bilayer nanoparticles.
Pyrazoline as a medicinal scaffold
Authors: Singh Gurinderdeep , Goyal Anju , Bhatti R S , Arora Sandeep
Published: November 2019

Heterocyclic Chemistry is the backbone of medicinal compounds that exhibits numerous biological activities. Pyrazole and its derivatives possess nitrogen atom along with carbon atom as a substitution and show a diversity of biological activities such as antibacterial, antimicrobial, anti-inflammatory, antioxidant, antidiabetic, anticancer, antifungal, antidepressant, anticonvulsant, analgesic, and monoamine oxidases (MAOs)as shown by pyrazoline prepared from chalcone(Intermediate). The synthesized compounds are checked by the TLC and further analyzed by the IR, NMR, and UV spectroscopy.
Prevalence of Human papillomavirus (HPV) genotypes in Ecuadorian women
Authors: Armijo Daniela , Sanchez Kianny
Published: November 2019

Infection with the human papillomaviruses (HPV) is now well-established as the leading cause in the development of cancer of the uterine cervix. HPV 16 and 18 are described as the most prevalent high-risk genotypes, involving about 70% of registered cervical cancer cases worldwide. Among women in the Ecuadorian population, cervical cancer is the second most frequent malignancy, and about 75% of active sexual women will be infected with at least one type of HPV genotypes throughout their lives. In the present investigation, the prevalence of HPV genotypes was determined from samples collected at Society for the Fight Against Cancer (SOLCA) in Ecuadorian women between 18 to 78 years. The participants underwent a Pap test, biopsy, cervical and vaginal swab for HPV detection and genotype identification. The results show the high prevalence index of HPV genotype 16 and 58, with a higher burden from the second to the fourth decade of life.
Diatom of Escape Bay in Myeik Archipelago, Southern Taninthayi Coast of Myanmar.
Authors: Ko Ko Zarni
Published: November 2019

A total of 53 species of diatom comprised 32 genera in the present study. The highest species composition (36 species) was found in July (monsoon season) and November (post-monsoon season), and the lowest number (23 species) was also found in October (post-monsoon season). Eucampia cornuta, Chaetoceros pervianum, C. compressus, and Surirella ovalis occurred rarely.
Study the effect of herbal mixture plants extract on blood sugar level in normal and experimentally diabetic mice
Authors: Allami Risala H. , Mohsin Raghdan H. , Mouhamad Raghad S.
Published: November 2019

The use of medicinal plants for the management of diabetes mellitus is an old practice that has become even more relevant in a modern perspective. The present work was designed to evaluate the effect of a mixture of three medicinal plants which used in folk medicine in Iraq, These plants are (Aloe vera, Artemisia herba alba, and Teucrium polium) on the levels of blood glucose in normal and alloxan-induced diabetic mice, The aqueous extract of the herbal mixture was prepared and chemical detection of phenols, flavonoids, tannins, terpenes, steroids, glycosides, and saponins was carried out. Results revealed that the aqueous extract contains phenols, flavonoids, tannins, terpenes, glycosides, and saponins compounds. Evaluations of the parameters of our study were carried out on both standard and alloxan-induced diabetic mice. Thirty male mice were randomly divided into six equal groups: Group I (control): was kept as control negative mice treated with only distilled water. Group II: normal mice treated with aqueous extract of an herbal mixture at a dose (500 mg/kg/day).Group III: normal mice treated with aqueous extract of an herbal blend at a dose (250 mg/kg/day). The other 3 groups were subcutaneously administered a single dose (100 mg/kg) of alloxan to induce experimental diabetes. Groups IV (Diabetic): was kept as control positive, alloxan-induced diabetic mice treated with only distilled water. Groups V: alloxan-induced diabetic mice treated with aqueous extract of an herbal mixture at a dose (500 mg/kg/day). Group VI: alloxan-induced diabetic mice treated with aqueous extract of an herbal blend at a dose (250 mg/kg/day), respectively, for ten days. Results showed that normal mice treated with aqueous extract has no significant change in body weights and blood glucose level except those treated with a high dose of aqueous extract since they exhibited a significant decrease (P ≤ 0.05) in blood glucose level. The results indicated a significant reduction in glucose level in diabetic mice after treatment with a high dose of aqueous extract of the herbal mixture. In conclusion, our results support that the aqueous extract of these plant exhibits anti-diabetic as compared with each plant alone, where we tested each of these plants in previous studies.
Meaningful Youth Participation as a way to achieving success
Authors: Van Reeuwijk Miranda
Published: November 2019

Youth participation is a key component in many youth sexual and reproductive health and rights (SRHR) programs. We analyze the results of Operational Research on Meaningful Youth Participation in a youth SRHR program in Ethiopia, Indonesia, Kenya, and Pakistan. Meaningful youth participation was found to have positive effects on empowerment and civic engagement of young people; on adult staff and organizations’ capacity to institutionalize meaningful involvement of young people, and provide youth-sensitive SRHR interventions; and achieve program objectives. Conditions enabling meaningful and structural youth participation are needed for positive effects, including mandates and policies on structural and fair youth representation at all decision making levels; opportunities for young people to have decision-making responsibilities, and to share power with adults; building young people’s capacities and understanding; welcoming and safe social environments where both young people and adults feel valued, respected, encouraged and supported.
Kualitas Pelayanan Surat Izin Mengemudi (SIM) Pada Kantor Satuan Lalu Lintas Polres Karimun
Authors: Sarmini Ade
Published: November 2019

Along with increasing population mobility and increasing road users the need to have a SIM is increasing every day. Where the administration of traffic and services, such as SIM, STNKB and BPKB are oriented to the principle of quick and easy without ignoring the identification and extension of the letter. This research uses descriptive research method. Descriptive research is intended to explore and clarify phenomena or social realities. From the results of the study showed that the implementation of public service quality in making SIMs at the Karimun Regional Police Traffic Unit Office was seen from the aspect of physical facilities (tangible), reliability (responsiveness), responsiveness, assurance and empathy were running pretty good. Especially relating to the ability and reliability to provide trusted services, the ability to help and provide services quickly and appropriately, as well as being responsive to consumer desires, abilities and friendliness and employee courtesy in assuring consumer trust and firm but attentive attitudes of employees towards consumers . Although it is indeed an inhibiting factor for SIM services such as human resources, the level of awareness and facilities and infrastructure are still found in the service of making SIMs at the Karimun Regional Traffic Unit Office
Retórica y educación: una propuesta interpretativa para la Retórica de Aristóteles
Authors: García-Aguilar Octavio
Published: November 2019

Durante los siglos cuarto y quinto antes de Cristo, en la ciudad-estado de Atenas se desarrolló un vivo debate alrededor de la pregunta ¿cómo educar? Los mecanismos heredados de la educación, la poesía homérica y la sabiduría gnómica comenzaron a ser reemplazados por teorías sistemáticas de la educación. Sin embargo, uno de sus más grandes teóricos, Aristóteles, legó una teoría incompleta debido a la desaparición de los libros de la Política que contenían el desarrollo de su teoría. Este ensayo plantea que se puede reconstruir parte de esta teoría interpretando la Retórica desde la pregunta por la educación. Para ello se expone como hipótesis que la Retórica contiene esbozos de una teoría de la educación, y se desarrollan tres argumentos principales: 1) la Retórica contiene una teoría de la educación, pues el joven, según los caracteres analizados por Aristóteles, no es una entidad política, por lo cual la Retórica además de política tiene un alcance educativo; 2) el discurso epidíctico teorizado en la Retórica tiene un carácter educativo, pues su finalidad consiste en transformar el comportamiento de los jóvenes conforme a los cánones establecidos por la teoría aristotélica de la educación; 3) existe un paralelismo entre palabra y música, ambos conceptos clave de la teoría fragmentaria de la educación esbozada en Política y Retórica. Con ello se concluye que la Retórica complementa la teoría educativa propuesta en la Política por Aristóteles.
Evaluación sumativa para la resolución de problemas en el área de Geometría
Authors: Zumbado-Castro Marianela
Published: November 2019

El presente artículo procura una respuesta a la siguiente interrogante ¿cómo evaluar de manera sumativa a los estudiantes cuando resuelven problemas de Geometría?, explorar las ideas a nivel internacional que aportan insumos a una propuesta evaluativa acorde con el MEP (2012). El proceso para conseguir lo deseado fue una investigación bibliográfica, a través de la cual se seleccionaron artículos con sólido respaldo teórico que abordan de manera simultánea tres tópicos: Geometría, resolución de problemas y evaluación de los aprendizajes, usando como criterio de discriminación similitudes con la fundamentación teórica de los programas de Matemáticas costarricense y excluyendo aquellos textos que no ofrecieran ejemplos concretos de sus propuestas. Para el análisis, la información se organizó de manera deductiva, partiendo de los elementos generales de la evaluación en educación matemática hasta las propuestas para temas específicos del área de Geometría. Dentro de los hallazgos más destacados se encuentran que la comunidad internacional realiza investigación en este campo y ha recurrido a diversas técnicas como el grupo focal, el análisis de HTE, el juicio de expertos y la entrevista cognitiva, para validar las herramientas generadas entre las que se encuentran las rúbricas, los ítems de selección múltiple y las respuesta construida, sobre temáticas como la visualización espacial, la descomposición y la composición de figuras. Se destaca que los procesos matemáticos se deben incluir en los instrumentos para evaluar el conocimientos de los estudiantes, pues permiten aproximar las competencias relacionadas con las Matemáticas.
Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress–Activated FOXO1 to Trigger β-Cell Failure
Authors: Triñanes Javier , ten Dijke Peter , Groen Nathalie , Hanegraaf Maaike , Porrini Esteban , Rodriguez-Rodriguez Ana E. , Drachenberg Cinthia , Rabelink Ton J. , de Koning Eelco , Carlotti Françoise , de Vries Aiko P.J.
Published: November 2019

Active maintenance of β-cell identity through fine-tuned regulation of key transcription factors ensures β-cell function. Tacrolimus, a widely used immunosuppressant, accelerates onset of diabetes after organ transplantation, but underlying molecular mechanisms are unclear. Here we show that tacrolimus induces loss of human β-cell maturity and β-cell failure through activation of the BMP/SMAD signaling pathway when administered under mild metabolic stress conditions. Tacrolimus-induced phosphorylated SMAD1/5 acts in synergy with metabolic stress–activated FOXO1 through formation of a complex. This interaction is associated with reduced expression of the key β-cell transcription factor MAFA and abolished insulin secretion, both in vitro in primary human islets and in vivo in human islets transplanted into high-fat diet–fed mice. Pharmacological inhibition of BMP signaling protects human β-cells from tacrolimus-induced β-cell dysfunction in vitro. Furthermore, we confirm that BMP/SMAD signaling is activated in protocol pancreas allograft biopsies from recipients on tacrolimus. To conclude, we propose a novel mechanism underlying the diabetogenicity of tacrolimus in primary human β-cells. This insight could lead to new treatment strategies for new-onset diabetes and may have implications for other forms of diabetes.
Eficacia y tolerabilidad del carbón activado más plata en el tratamiento local de heridas infectadas
Authors: Heras Veloz Martha Cecilia , Pozo Camacho Consuelo , Galán Sánchez Rodolfo , Uraga Pazmiño Enrique
Published: November 2019

Actualmente la terapia basada en el principio de proveer humedad en el ambiente de una herida se conoce como cuidado avanzado de heridas. Existe una gran cantidad de apósitos activos que se utilizan en hospitales y centros privados por ejemplo, los que contienen carbón activado más plata, hidrocoloides, alginatos, hidropolímeros, todos ellos promueven humedad y debridamiento autolítico. El propósito de este estudio fue valorar la eficacia y tolerabilidad del carbón activado más plata en heridas infectadas. Dieciséis pacientes (10 mujeres y 6 hombres) con úlceras de diversa etiología internados en el servicio médico de Dermatología del hospital Luis Vernaza, Guayaquil formaron parte de este estudio por un tiempo de 4 años. Se registró el tamaño de las heridas y se realizaron cultivos bacterianos de las úlceras, el registro fotográfico; se realizó al inicio y en cada recambio de apósito. De los dieciséis pacientes solo uno abandonó el estudio, una paciente epitelizó el 100%, en los restantes se observó aumento del tejido de granulación y disminución del exudado. El objetivo del estudio fué preparar las ulceras para tratamiento quirúrgico, salvo el caso que epitelizó el 100%,el cual deja una ventana abierta en pacientes seleccionados en donde se puede llegar al cierre definitivo. El tejido periulceral permaneció indemne durante todo el tratamiento. Este estudio propone que el tratamiento local de heridas infectadas con carbón activado más plata, es eficaz ya que permite un apropiado manejo de la infección bacteriana y un correcto ambiente húmedo.
The Population Health Research Network - Population Data Centre Profile
Authors: Flack Felicity , Smith Merran
Published: November 2019

The Population Health Research Network (PHRN) is an Australian data linkage infrastructure capable of securely and safely linking and integrating data collections from a wide range of sources. It is an example of a national data linkage infrastructure in a country with a federated system of government. This population data centre profile describes Australia’s unique approach to enabling access to linked data from single jurisdictions and from multiple jurisdictions. It covers the background to the establishment of the PHRN as well as information about how it operates today including operating models, governance, data, data linkage and data access. Some of the challenges of data linkage across jurisdictions are also discussed.
Filosofía: de la fábrica a la empresa y la psicopolítica
Authors: Ávila Barba Mauricio
Published: November 2019

La incorporación de la universidad pública a la lógica de la empresa y del mercado, así como las consecuencias que ello ha traído para los programas educativos en filosofía, se han denunciado desde diferentes instancias, tales como el Observatorio Filosófico de México. Por ejemplo, se denuncia que, bajo esta lógica, la filosofía está en riesgo de desaparecer, que ella debería ser valorada por su posibilidad formativa de ciudadanos, entre otros reclamos. Sin embargo, paradójicamente, esta lógica también ha definido muchas de las prácticas docentes y de investigación que implican “beneficios” para los profesores, tales como estímulos y apoyos económicos. Esto complica toda denuncia emitida sobre la situación de la filosofía, por lo que se requiere una vía de análisis que dé cuenta de esta paradoja. En este sentido, el objetivo de este trabajo es definir y proponer un análisis psicopolítico de la empresarización de la universidad pública, y con ello de los programas educativos en filosofía que esta alberga, que nos permita dar cuenta de las tensiones antes mencionadas. Así, consideramos que describir esta paradoja nos permitiría un conocimiento adecuado de la situación de la filosofía y, quizá con ello, tomar mejores decisiones para hacer frente o no a la empresarización de la universidad.

            Para caracterizar este fenómeno universitario tomamos como hilo conductor dos perspectivas: primero, la discusión sobre la pertinencia de los programas educativos en filosofía (universidad-demanda laboral); y, segundo, la definición de las nociones de universidad-responsabilidad social, universidad-calidad y universidad-evaluación. Estas ideas las definimos a través de una breve investigación documental, la cual nos arroja como resultado que la filosofía está sujeta a lo siguiente: 1) los estándares de la marca ISO, 2) los diagnósticos sobre su impacto social y, eventualmente, ecológico, 3) los cánones de calidad, eficiencia, productos y servicios, 4) las sugerencias de la Organización Mundial del Trabajo, 5) las demandas del mercado; entre otras características descritas en este trabajo. Estos resultados los discutimos a la luz de las nociones de fábrica y empresa y de psicopolítica, propuestas por Gilles Deleuze y Byung-Chul Han, respectivamente.

            Finalmente, asumiendo el panorama de la empresarización de las universidades, realizamos una reflexión prospectiva para sugerir acciones que permitirían hacer frente a esta lógica: primero, más diagnósticos sobre los lineamientos y prácticas empresariales que van trazando la ruta de desarrollo de las universidades; y, segundo, la ampliación de los perfiles de egreso en los programas educativos de licenciatura en filosofía a través de la caracterización de nuevos campos profesionalizantes y de prácticas de la filosofía
BUILDING INTERPERSONAL ABILITY OF ELEMENTARY SCHOOL STUDENTS BY PLAYING TRADITIONAL GAME IN DIGITAL ERA
Authors: Anggia Nastitie Ariawan Vina , Kuswendi Uus , Subarkah Subarkah
Published: November 2019

Nowadays, students prefer to have online game rather than traditional one. Online game led to the lack of student’s interaction with people around them, they have high individualistic, and shirk responsibility. Traditional game can be an alternative to decrease bad effects of online game. Consequently, this research aims to build interpersonal ability of elementary school students by doing traditional game. This research employed action research method with fifth grade students as its subject. Interpersonal ability which showed in this research was measured by observation meanwhile the instruments of observation consist of field note and rating scale. The outcome from this research was analysed by thematic analysis meanwhile the data was validated by triangulation. Referring to research’s findings, researcher concludes that traditional game offer meaningful activities and different experiences to the students. Traditional game motivate students to doing physical acitivities and make interaction with peers. Moreover, a meaningful moral values will evolve among the students by themselves. Traditional game can be used as media to building interpersonal ability of students. Besides that, teacher can introduce the traditional game to students to keep the local wisdom that almost wiped out.
PENGEMBANGAN MODUL PEMBELAJARAN BERBASIS SCIENCE TECHNOLOGY SOCIETY (STS) DISERTAI MIND MAP
Authors: i Listiani Ivayun
Published: November 2019

The purpose of this study is to develop a learning module based Science Technology Society (STS) complete with Mindmap. This research is a development (Research and Development) or the so-called R and D research which refers to the Borg and Gall modified. The research sample development includes: 1) sample field trials beginning some 6 validators; 2) Samples major field trial a number of 10 students of Grade X at Public Senior High School and operational field testing samples of up to 27 students of Grade X at Public Senior High School. The instrument used was a questionnaire, observation sheets, and interviews. Operational field trials using the one group pretest-posttest design. Based on the results of the study it can be concluded learning modules based STS with Mindmap were developed using a development model Borg and Gall through the stages of research and information collecting, planning, develop preliminary form of product, preliminary field testing, main product revision, playing field testing, operational product revision, field operational testing, final product revision, and dissemination and implementation.
PENGARUH TAX AMNESTY, PERTUMBUHAN EKONOMI, KEPATUHAN WAJIB PAJAK TERHADAP PENERIMAAN PAJAK DI KPP PRATAMA PEKANBARU TAMPAN
Authors: Wahidah Ari Nur
Published: November 2019

Penelitian ini bertujuan untuk membuktikan secara empiris pengaruh tax amnesty, pertumbuhan ekonomi kepatuhan wajib pajak, terhadap penerimaan pajak. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan data primer yang diperoleh dari kuesioner dan diukur dengan menggunakan skal likert. Populasi penelitian ini adalah wajib pajak orang pribadi (WP)  yang terdaftar dikantor pelayanan pajak pratama pekanbaru Tampan sebanyak 100 orang. Metode pemilihan sampel menggunakan incidental sampling, yaitu siapa yang secara kebetulan bertemu dengan peneliti digunakan sebagai sampel serta cocok sebagai sumber data. Tehnik analisis data yang digunakan adalah analisis regresi linear berganda dengan menggunakan SPSS 17.0 for Windows. Hasil penelitian menunjukkan bahwa secara parsial dan simultan tax amnesty, pertumbuhan ekonomi, kepatuhan wajib pajak berpengaruh positif dan signifikan terhadap penerimaan pajak.
Интериктальная эпилептиформная активность во сне и в бодрствовании у пациентов с височной эпилепсией
Authors: Брутян А. Г. , Белякова-Бодина А. И. , Долгова С. М. , Пушкарь Т. Н. , Абрамова А. А.
Published: November 2019

Сон является значимым активатором эпилептиформной активности, при этом вероятность регистрации разрядов может меняться в зависимости от стадии и глубины сна. Целью исследования было оценить зависимость эпилептиформной активности от уровня бодрствования и глубины сна в популяции взрослых пациентов с височной локализацией разрядов. Нами было проанализировано 32 продолженных ЭЭГ-мониторинга с записью ночного сна, в которых были отмечены все фокальные разряды, а также проводилось стадирование сна. Определяли общий индекс эпилептиформной активности, как отношение общего количества разрядов к длительности исследования в часах, а также индивидуальные индексы эпилептиформной активности для бодрствования и каждой из стадий сна: для REM-фазы и N1, N2 и N3 стадий NREM-сна. У подавляющего числа пациентов (28) максимальный индекс зарегистрирован в стадии N3. По мере перехода к более глубоким стадиям сна, индекс разрядов последовательно и достоверно увеличивался, достигая максимальных величин в стадии N3 (p < 0,01). В фазу REM-сна индекс резко снижался (p < 0,01), приближаясь к значениям, зарегистрированным в бодрствовании. Основным механизмом, который приводит к увеличению индекса эпилептиформной активности в NREM-сне, может быть нарастающая синхронизация корковых нейронов с увеличением доли медленной активности в ЭЭГ. Таким образом, стадия N3 является наиболее информативной в плане регистрации фокальных разрядов, что диктует необходимость достижения достаточной глубины сна при проведении диагностических ЭЭГ исследований у пациентов с височными формами эпилепсии.
Клинический пример восстановления проходимости печеночной вены и портосистемного шунта через 10 лет после TIPS
Authors: Цициашвили М. Ш. , Шиповский В. Н. , Монахов Д. В. , Челяпин А. С. , Гусейнов А. Б.
Published: November 2019

Одним из немногих доступных методов борьбы с осложнениями портальной гипертензии у пациентов с хроническими диффузными заболеваниями печени является трансъюгулярное портосистемное шунтирование. С течением времени имеется тенденция к развитию дисфункции внутрипеченочного шунта вследствие нарушения его проходимости, что вновь приводит к развитию осложнений портальной гипертензии. Описанный клинический случай демонстрирует возможности внутрипеченочного шунтирования, а также повторных эндоваскулярных вмешательств при дисфункции шунта, позволяющих значительно продлить жизнь пациента и сохранить ее качество.
Peningkatan Aktivitas dan Hasil Belajar Matematika Tema Pengalamanku dengan Model Pembelajaran Course Review Horay
Authors: Suprihartini Suprihartini
Published: November 2019

Tujuan penelitian ini adalah untuk aktivitas dan hasil belajar matematika tema pengalamanku dengan model pembelajaran course review horay bagi siswa kelas I SD 3 Tenggeles semester II Tahun Pelajaran 2017/2018. Penelitian tindakan kelas dilakukan pada siswa kelas I SD 3 Tenggeles semester I Tahun Pelajaran 2017/2018dengan jumlah siswa 15 terdiri dari 7 siswa putra dan 8 siswa putri. Metode yang digunakan dalam penelitian ini adalah penelitian tindakan kelas yang terdiri dari 2 siklus, masing-masing siklus terdiri dari 4 tahapan yaitu perencanaan, pelaksanaan, pengamatan, dan refleksi. Pada siklus 1 dan 2 tindakan yang dilakukan dengan model pembelajaran course review horay. Hasil penelitian berdasarkan hasil penelitian dan pembahasan, disimpulkan bahwa penggunaan model pembelajaran course review horay dapat meningkatkan aktivitas dan hasil belajar matematika tema pengalamanku bagi siswa kelas I SD 3 Tenggeles Kecamatan Mejobo Kabupaten Kudus Semester II Tahun Pelajaran 2017/2018. Sebagai indikasinya: (1) Aktivitas belajar matematika tema pengalamanku terus meningkat pada tiap siklus. Kondisi awal aktivitas belajar 69, siklus I meningkat menjadi 74 dan siklus II mencapai 78. Dari kondisi awal ke kondisi akhir terjadi peningkatan sebesar 9; (2) Hasil belajar matematika tema pengalamanku terus meningkat pada tiap siklus. Kondisi awal hasil belajar 69, siklus I meningkat menjadi 72 dan siklus II mencapai 88. Dari kondisi awal ke kondisi akhir terjadi peningkatan sebesar 20.
Linguistic competence, Communicative Competence and Interactional Competence
Authors: Chathamkulam Abdulrahman Nishad , Abu-Ayyash Emad A. S.
Published: November 2019

Linguistic competence, communicative competence, and interactional competence have had profound impact on second language teaching, learning, and testing. Although a significant number of studies have been conducted on these three competences, they have not been conflated for discussion in a single study. Adding this piece to the jigsaw, the current paper explores all the three competences in more depth. This paper had a twin purpose of 1) providing a historical account of the linguistic, communicative and interactional competences, and 2) reviewing of the literature on them in order to identify gaps, if any, with the intention to propose new research ideas pertinent to the three types of competence. In order to achieve the study aims, intensive literature survey was conducted.  Based on the review of the related studies on linguistic, communicative and interactional competences, this article provides recommendations for effective classroom practice and future research.
New look at an old principle: an alternative formulation of the theorem of minimum entropy production
Authors: Vincze Gyula , Szasz Andras
Published: November 2019

We formulate a direct generalization of the Prigogine’s principle of minimum entropy production, according to a new isoperimetric variation principle by classical non-equilibrium thermodynamics. We focus our attention on the possible mathematical forms of constitutive equations. Our results show that the Onsager’s reciprocity relations are consequences of the suggested variation principle. Furthermore, we show by the example of the thermo-diffusion such reciprocity relations for diffusion tensor, which are missing in Onsager’s theory. Our theorem applied to the non-linear constitutive equations indicates the existence of dissipation potential. We study the forms of general reciprocity with the dissipation potential. This consideration results in a weaker condition than Li-Gyarmati-Rysselberhe reciprocity has. Furthermore, in the case of electric conductivity in the magnetic field, our theorem shows the correct dependence of the Onsager’s kinetic coefficient by the axial vector of magnetic induction. We show in general that the evolution criterion of the global entropy production is a Lyapunov-function, and so the final stationer state is independent of the initial, time-independent boundary conditions.
Chemical Changes in Strained Dairy Product Produced with Organic Milk by Using Kefir Grains and Yogurt Culture during Refrigerated Storage
Authors: GULER Zehra , TEKİN Ali , DURSUN Ahmet
Published: November 2019

The objective of this study was to produce a

strained dairy product made from organic milk using yogurt culture and kefir

grains as a new product development. Strained dairy product was analyzed for carbohydrates,

organic acids, volatile organic compounds (VOCs), basic chemical composition as

well as overall acceptability at 1, 7, 14, 21 and 28 days of refrigerated

storage. While galactose content in dairy products increased, lactose and glucose

contents decreased on 14th day of storage. The main VOC was ethanol,

accounted for about 58% of total volatiles. An increase in succinic acid (from 312

mg/kg to 638 mg/kg), acetic acid (632 mg/kg-843 mg/kg), ethyl octanoate (1.07%-4.15%)

and a decrease in viscosity (5754 mPas-1050 mPas) and total solids (24.33%-20.64%)

towards the end of storage were observed. Refrigerated storage for more than 21

days could not be recommended since the product was found unacceptable by the

panelists but the product consumption at the first 21 days of storage may be an

advantage for lactose intolerance humans due to its low lactose level.
Kuru İncirin İşlenmesi, Kalite Problemleri ve Gıda Endüstrisinin Geliştirdiği Yenilikçi Yöntemler
Authors: GENÇDAĞ Esra , GÖRGÜÇ Ahmet , YILMAZ Fatih Mehmet
Published: November 2019

Türkiye, sahip olduğu özel

ekolojik koşullar sayesinde farklı türlerde incir zenginliğine sahip ve aynı

zamanda kurutmalık ve sofralık incir yetiştiriciliğinde ve ticaretinde dünyada lider

konumdadır. Özellikle kurutmaya en uygun olan Sarılop çeşidi incir, ülkemizde toplam incir üretiminin %90’ından

fazlasına karşılık gelen önemli bir ihracat ürünüdür. Kuru incir üretiminde

gözlenen kalite problemleri yetiştiricilik, hasat, kurutma, işleme ve depolama

süreçlerinin hepsinden ileri gelebilmektedir. Bu yüzden, kuru incir üretiminde bahçeden

itibaren işlenip ambalajlanana kadar birçok zirai ve teknolojik önlem

alınmaktadır. Kuru incirde önemli bir gıda güvenliği problemi olan aflatoksin

bulunma riski bu konuda çok sayıda çalışma yapılmasını sağlamıştır. Gıda

endüstrisi, kaliteli kuru incir üretiminin sağlanması amacıyla alternatif

yöntemler geliştirmekte ve bu yöntemlerin işletmelerde kullanılabilirliği test

edilmektedir. Kuru incir işlemede metil bromitin yerine kullanılabilecek fümigasyon

tekniklerin aranması, yeni analiz yöntemlerinin geliştirilmesi ve kuru incir

işleme hattında bilgisayar - algoritma tabanlı görüntüleme tekniklerinin

kullanımı söz konusu yeni teknolojilerden bazılarıdır. Bu derleme kapsamında, güncel

çalışmalar takip edilerek kuru incir üretimi, kalite problemleri ve kuru incir

işlemede geliştirilen yenilikçi yöntemler hakkında bilgi verilmiştir.
Gıdalarda Deniz Kaynaklı Makroalg Özütü Kullanımı ve Lipit Oksidasyonunu Önlemede Antioksidan Etkisi
Authors: GÜMÜŞ Bahar , GÜMÜŞ Erkan
Published: November 2019

Katkı maddesi içermeyen doğal ürünlere yönelik artan

tüketici talepleri ve yeni üretim teknikleri doğal katkı maddelerine olan

ilgiyi arttırmıştır. Antioksidanlar, az miktarlarda kullanımıyla bile yağ

oksidasyonunu engelleyen ya da geciktiren gıda katkı maddelerinin önemli bir

grubudur. Gıdalarda, butil hidroksianisol, butil hidroksitoluen ve tersiyer bütil hidroksikinon gibi sentetik

antioksidanlar ya da tokoferoller, askorbik asit, karotenoidler, flavonoidler,

aminoasitler, fosfolipidler ve steroller gibi doğal antioksidanlar

kullanılmaktadır. Son zamanlarda, gıda endüstrisi doğal antioksidan maddelerin

ekstraksiyonu ve saflaştırılması üzerine odaklanmıştır. Bu nedenle, antioksidan

bileşenlerin iyi bir kaynağı olarak makroalg özütlerine olan ilginin arttığı

görülmektedir. Literatürde, deniz kökenli makroalg özütlerinin (özellikle

kahverengi makroalglerin) güçlü antioksidan özelliklere sahip olduğu rapor

edilmektedir. Pek çok araştırmada, farklı makroalg türlerinden, klorofil, β-karoten, α-tokoferol, askorbik

asit, niasin, tiamin, polifenol, polisakkaritler, flavonoidler, fosfolipidler,

terponoidler ve peptidler gibi antioksidan bileşenler ekstrakte edilmiştir.

Araştırmacılar tarafından, makroalg özütlerinin antioksidan özellikleri üzerine

farklı coğrafik bölge, makroalg türleri, çözücüler, ekstraksiyon metodu,

ekstraksiyon sıcaklığı ve zamanı gibi bazı parametrelerin etkileri

araştırılmıştır. Bu derlemenin amacı, makroalg özütlerinin antioksidan

aktivitesi üzerine yapılan bilimsel makalelerin sonuçlarını sunmak ve gıdalarda

antioksidan maddelerin doğal bir kaynağı olarak potansiyeli hakkında bilgi

vermektir.
Incorporation of EGFR mutation status into M descriptor of new TNM classification influences survival curves in non-small cell lung cancer patients
Authors: Stanic Karmen , Turnsek Nina , Vrankar Martina
Published: November 2019

Background

The 8th edition of tumor node metastasis (TNM) staging system for lung cancer introduced a revision of M descriptor. The limitation of new classification to predict prognosis is its focus on anatomical extent of the disease only. Information on molecular status of the tumor significantly influences treatment response and survival; however, data addressing this issue is scarce. This report points to the impact of epidermal growth factor receptor (EGFR) mutation in non-small cell lung cancer (NSCLC) patients on survival in view of new M descriptors of TNM classification system.

Patients and methods

Medical records of 479 consecutive metastatic NSCLC patients treated between 2009 and 2011, all tested for EGFR mutations, were retrospectively reviewed. For 355 patients medical records included sufficient information to be appropriately categorized into one of the new subgroups according to the M descriptor in 8th TNM classification, of those 89 (25.1%) patients harboured EGFR mutations (EGFR-m).

Results

Median overall survival (mOS) of EGFR-m patients was significantly longer than mOS of patients without EGFR mutations (20.6 months vs. 8.3 months, p < 0.001). Patients with limited disease burden (M1b sub-group) had the longest mOS among EGFR wild type patients (EGFR-wt) and also among EGFR-m patients, 14.4 months and 39.2 month, respectively. In spite of widespread metastatic disease of M1c EGFR-m patients, their mOS (18.8 months) was longer than mOS of oligometastatic EGFR-wt patients (M1b), who had the lowest disease burden (14.4 months). Median follow up was 53.9 months.

Conclusions

Incorporation of EGFR mutation status in advanced NSCLC further differentiates survival curves of M categories in 8th TNM classification and more precisely predicts survival compared to number of metastasis or number of metastatic sites alone.
INNOVATION OF THE TRADITIONAL SANDSTONE CRAFT PRODUCTS IN THE GLOBALIZATION ERA AT NORTH SINGAPADU VILLAGE GIANYAR
Authors: Pendet I Ketut Muka , Ardhana I Ketut , Suarka I Nyoman , Sugiartha I Gede Arya
Published: November 2019

Nowadays the process through which the sandstone craft products are produced at North Singapadu Village has changed. The appearance of different types of popular sandstone craft products reflecting the local identity produced by the young craftsmen at North Singapadu Village shows this. Such products are different from the traditional sandstone craft ones in terms of form and aesthetic style. Globalization, ideology and technology have basically led to the change. The sandstone industry has become highly innovative. This present study uses the qualitative and interpretative method and the theories used are the theory of acculturation, the theory of deconstruction, and the theory of postmodern aesthetics.

             The conclusion of the present study is that the form and process of innovation initially resulted from new ideas and concepts and the craftsmen’s paradigm. The main things which have been responsible for changing the traditional way of life into the modern way of life are formal education, tourism and modern technologies. Those who are positively and negatively affected by globalization are not only the capital owners and craftsmen but the villagers and consumers as well. The sandstone craft products at North Singapadu Village contain the meaning of creativity, the economic meaning, the commodificative meaning and the meaning of cultural change. The finding of the study shows that the craftsmen at North Singapadu Village have ignored the traditional concepts, the technique of producing the products, and the materials used. However, the sandstone craft products at North Singapadu Village do not get extinct but remain to exist and both domestic and foreign consumers are interested in them.
COMPASSIONATE CAPITALISM IN HOTEL INDUSTRY IN UBUD, BALI
Authors: Sanjaya I Wayan Kiki , Mudana I Gede
Published: November 2019

This present study analyzes the success of the practice performed by the investors in hotel industry using the ideology of the compassionate capitalism. The study was conducted in Ubud as the habitus of the investors in hotel industry. The area has the characteristic of tending to be resistant and strongly bound to customs and traditions, and is skeptical to the gradual modern impact. The problem of the study is what the practice of the compassionate capitalism performed by the investors of hotel industry in Ubud like. The study is intended to identify the form of the practice performed by the investors in hotel industry in Ubud as a tourist destination, Gianyar Regency, Bali. The qualitative-interpretative method was used. The data were collected using observation, interview and documentation techniques. The data were analyzed through data reduction, data presentation, and conclusion drawing using the theories of cultural studies which are eclectically related. The result of the study identifies that the investors in hotel industry in Ubud perform their practices by: (1) using the Company Social Responsibilities (CSR) as the basis for performing their practice in hotel industry; (2) adopting the local genius stated in the community-based tourism, CBT). The finding of the study indicates that the investors use the structural pattern of the compassionate capitalism which adapts to capitalism in the case study of hotel industry.