bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Interpretation of the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function Scale for Specific Tasks in Community-Dwelling Older Adults
Authors: Houck Jeff , Jacobson Ryan , Bass Michael , Dasilva Chris , Baumhauer Judith F.
Published: February 2019

Background and Purpose:

New generic patient-reported outcomes like the Patient-Reported Outcomes Measurement Information System (PROMIS) are available to physical therapists to assess physical function. However, the interpretation of the PROMIS Physical Function (PF) T-score is abstract because it references the United States average and not specific tasks. The purposes of this study were to (1) determine convergent validity of the PROMIS PF scale with physical performance tests; (2) compare predicted performance test values to normative data; and (3) identify sets of PROMIS PF items similar to performance tests that also scale in increasing difficulty and align with normative data.

Methods:

Community-dwelling older adults (n = 45; age = 77.1 ± 4.6 years) were recruited for this cross-sectional analysis of PROMIS PF and physical performance tests. The modified Physical Performance Test (mPPT), a multicomponent test of mostly timed items, was completed during the same session as the PROMIS PF scale. Regression analysis examined the relationship of mPPT total and component scores (walking velocity, stair ascent, and 5 times sit to stand) with the PROMIS PF scale T-scores. Normative data were compared with regression-predicted mPPT timed performance across PROMIS PF T-scores. The PROMIS PF items most similar to walking, stair ascent, or sit to stand were identified and then PROMIS PF model parameter–calibrated T-scores for these items were compared alongside normative data.

Results and Discussion:

There were statistically significant correlations (r = 0.32-0.64) between PROMIS PF T-score and mPPT total and component scores. Regression-predicted times for walking, stair ascent, and sit-to-stand tasks (based on T-scores) aligned with published normative values for older adults. Selected PF items for stair ascent and walking scaled well to discriminate increasing difficulty; however, sit-to-stand items discriminated only lower levels of functioning.

Conclusions:

The PROMIS PF T-scores showed convergent validity with physical performance and aligned with published normative data. While the findings are not predictive of individual performance, they improve clinical interpretation by estimating a range of expected performance for walking, stair ascent, and sit to stand. These findings support application of T-scores in physical therapy testing, goal setting, and wellness plans of care for community-dwelling older adults.
Assessment of Gait Speed in Older Adults
Authors: Mehmet Hanife , Robinson Stephen R. , Yang Angela Wei Hong
Published: February 2019

Background and Purpose:

Gait speed is an important measure of functional ability and has been widely used in older adults as an indicator of frailty. However, the diversity in measurement protocols in clinical settings creates variability in outcome measures. The aim of this study was to systematically review the literature relating to the measurement of gait speed in older adults, to propose a protocol suitable for use in clinical and community settings.

Methods:

A total of 5 electronic English databases were searched (PubMed, EMBASE, AMED, CINAHL, and SPORTDiscus) using key words and synonyms related to gait speed.

Results:

Fifty relevant articles were identified, with variability being found between studies in the essential elements (timing device, walking distance, timing points, use of walking aids, pace of performance, and total tests recorded) of gait measurement. The majority of studies used unspecified timing devices while others used electronic gait mats or infrared beams linked to electronic stopwatches. Walking distance was assessed over distances between 2.4 and 15 m, with 4 m most commonly used. Most studies permitted the use of walking aids, with assessments being repeated at a usual pace, and the maximum value recorded in meters per second.

Conclusion:

A standardized measurement protocol is proposed for measuring gait speed in older adults.
Borderline Personality Disorder Symptom Comorbidity Within a High Externalizing Sample: Relationship to the Internalizing-Externalizing Dimensional Structure of Psychopathology
Authors: Bailey Allen J. , Finn Peter R.
Published: February 2019

Borderline personality disorder (BPD) is highly comorbid with internalizing and externalizing psychopathology. The current study replicates findings indicating that BPD symptomatology is influenced by the distress subfactor of both the internalizing and the externalizing dimension of psychopathology. Confirmatory factor analysis of the covariance of continuous measures of externalizing pathology, internalizing pathology, and BPD symptoms was assessed in 837 young adults. The sample contained a range of externalizing severity from none to high severity, leading to an overrepresentation of externalizing problems. BPD symptoms were associated with both the externalizing dimension and the distress subfactor of the internalizing dimension. Interestingly, BPD had a stronger association with the externalizing dimension than observed in previous studies. Results replicated earlier findings using different and more dimensional measures. Findings indicated that BPD is more heavily influenced by the externalizing dimension of psychopathology within a high externalizing sample, such as those presenting for treatment of alcohol or substance use disorders.
The Food-Energy-Water Nexus, Regional Sustainability, and Hydraulic Fracturing: An Integrated Assessment of the Denver Region
Authors: Ahamed Sonya , Sperling Joshua , Galford Gillian , Stephens Jennie C. , Arent Douglas
Published: February 2019

Intersections of food, energy, and water systems (also termed as the FEW nexus) pose many sustainability and governance challenges for urban areas, including risks to ecosystems, inequitable distribution of benefits and harms across populations, and reliance on distant sources for food, energy, and water. This case study provides an integrated assessment of the FEW nexus at the city and regional scale in ten contiguous counties encompassing the rapidly growing Denver region in the United States. Spatial patterns in FEW consumption, production, trans-boundary flows, embodied FEW inputs, and impacts on FEW systems were assessed using an urban systems framework for the trans-boundary food-energy-water nexus. The Denver region is an instructive case study of the FEW nexus for multiple reasons: it is rapidly growing, is semi-arid, faces a large projected water shortfall, and is a major fossil fuel and agricultural producer. The rapid uptake of high-volume hydraulic fracturing (HVHF) combined with horizontal drilling in populated areas poses ongoing risks to regional water quality. Through this case study, fracking is identified as a major topic for FEW nexus inquiry, with intensifying impacts on water quantity and quality that reflect nationwide trends. Key data gaps are also identified, including energy for water use and food preparation. This case study is relevant to water and sustainability planners, energy regulators, communities impacted by hydraulic fracturing, and consumers of energy and food produced in the Denver region. It is applicable beyond Denver to dry areas with growing populations, agricultural activity, and the potential for shale development.
DZNep and UNC0642 enhance in vitro developmental competence of cloned pig embryos
Authors: Zhao Chengfa , Shi Junsong , Zhou Rong , He Xiaoyan , Yang Huaqiang , Wu Zhenfang
Published: February 2019

Somatic cell nuclear transfer in mammalian cloning suffers from a faulty epigenetic reprogramming, which is believed to cause developmental failures in cloned embryos. Regulating the epigenetic-modifying enzymes can rescue the chromatin of cloned embryos from aberrant epigenetic status, thereby potentially promoting cloning efficiency. In this study, we investigated the effect of two histone methyltransferase inhibitors, namely, DZNep and UNC0642, on the in vitro developmental competence of cloned pig embryos. We found that (1) treatment with 10 nM DZNep or 5 nM UNC0642 for 24 h after activation had the best promoting effect on the development of cloned embryos (blastocyst rate 10.32% vs 18.08% for DZNep, and 10.44% vs 18.14% for UNC0642); (2) 10 nM DZNep and 5 nM UNC0642 significantly decreased the levels of H3K27me3 and H3K9me2, respectively, at the 2-cell, 4-cell and blastocyst stages; (3) the apoptosis level was lower in the treatment groups than in untreated control; and (4) the transcriptional expression of epigenetic genes (EZH2, GLP, G9a, Setdb1, Setdb2, Suv39h1 and Suv39h2) was decreased and pluripotency genes (Nanog, Pou5f1, Sox2 and Bmp4) was increased in treatment groups compared with control. These results indicated that treatment with DZNep and UNC0642 improves the epigenetic reprogramming of cloned embryos, which could render beneficial effect on the embryo quality and aberrant gene expression, and finally improve the developmental competence of cloned pig embryos.
Empowerment and associative process of rural women: a case study of rural areas in Bogotá and Cundinamarca, Colombia
Authors: Suárez Eliana , Mosquera Teresa , Del Castillo Sara
Published: February 2019

There are no formal female food production organizations in the municipalities of Sibate, Sopo or Sumapaz (Bogotá rural area). Additionally, in the organizations in which women participate, they usually do not hold a decision-making position, which inhibits economic and social development despite the fact that women play an important role in the entire food system (production, preparation, consumption and food utilization). The aim of this research was to characterize the empowerment of rural women as a consequence of associative processes that contribute to food and nutrition security using the "descriptive case" qualitative research methodology. The main results indicated that, even though the participation of women in associative processes promotes decision-making, access to agricultural inputs, technical assistance and economic autonomy, there are still inequalities and inequities between men and women. For these reasons, it is necessary to strengthen associative processes with a cross-cutting gender approach and provide space for participation where both women and men analyze and question traditional roles in the household in order to transform inequity gaps and, therefore, contribute to food and nutrition security.
Prevalence of Chlamydia trachomatis infection diagnosed by polymerase chain reaction in female sex workers in a Northern Mexican City
Authors: Sánchez-Anguiano Luis Francisco , Velázquez-Hernández Nadia , Guerra-Infante Fernando Martín , Aguilar-Durán Marisela , Pérez-Álamos Alma Rosa , Estrada-Martínez Sergio , Navarrete-Flores José Antonio , Sandoval-Carrillo Ada Agustina , Antuna-Salcido Elizabeth Irasema , Hernández-Tinoco Jesús , Alvarado-Esquivel Cosme
Published: February 2019

Purpose: We aimed to determine the association between Chlamydia trachomatis infection and female sex work, and the association between sociodemographic, obstetric, and behavioral characteristics of female sex workers and C. trachomatis infection.

Methods: Through a case–control study design, we studied 201 female sex workers and 201 age-matched women without sex work in Durango City, Mexico. C. trachomatis DNA was detected in cervical swab samples using polymerase chain reaction.

Results: C. trachomatis DNA was detected in 32 (15.9%) of the 201 cases and in 6 (3.0%) of the 201 controls (odds ratio [OR] = 6.15; 95% confidence interval [CI]: 2.5–15.0; P < 0.001). The frequency of infection with C. trachomatis in female sex workers did not vary (P > 0.05) regardless of the history of pregnancies, deliveries, cesarean sections, or miscarriages. Regression analysis of the behavioral characteristics showed that infection with C. trachomatis was associated only with consumption of alcohol (OR = 2.39; 95% CI: 1.0–5.71; P = 0.04).

Conclusions: We conclude that C. trachomatis infection is associated with female sex work in Durango City, Mexico. This is the first age-matched case–control study on the prevalence of C. trachomatis infection in female sex workers in Mexico using detection of C. trachomatis DNA in cervical samples.
Li–Fraumeni-szindróma
Authors: Sejben Anita , Tiszlavicz László , Polyák Kornélia , Kovács László , Maráz Anikó , Török Dóra , Leprán Ádám , Ottlakán Aurél , Furák József
Published: February 2019

Abstract:

Li-Fraumeni syndrome is a rare genetic disorder predisposing the individual to multiple different cancer types, caused by a germline mutation of the TP53 or CHEK2 genes inherited in an autosomal dominant manner. We hereby describe the case of a family with Li–Fraumeni syndrome. An asymptomatic 40-year-old female was diagnosed with primary lung leiomyosarcoma (T3N0), adenocarcinoma (T1aN0), and inflammatory myofibroblastic tumor, which were surgically removed without further treatment. Twenty months later she underwent surgery for retroperitoneal liposarcoma and even though she received adjuvant chemotherapy, deceased shortly after. Due to family history, the patient underwent TP53 mutation testing, using peripheral blood genomic DNA, which identified a heterozygous, likely pathogenic missense mutation (c.722C>G p.Ser241Cys) in case of the mother and her son. Three years after the patient’s death, her 17-year-old son was diagnosed with a 3.5 cm osteosarcoma of the right second rib, which was surgically removed, followed by adjuvant chemotherapy. However, despite treatment, he deceased after two years. Throughout four generations of the patient’s family, 10 malignant tumors (stomach-, breast-, 2 lung-, and colon cancer, leukemia, leiomyosarcoma, liposarcoma and 2 osteosarcoma) were diagnosed with a mean age of 43.2 (13–70 years) years. The simultaneous appearance of primary lung leiomyosarcoma, inflammatory myofibroblastic tumor and adenocarcinoma in the same organ is extremely rare. When possible, surgical resection should be carried out. Genetic testing for TP53 is recommended when family history is suggestive of Li–Fraumeni syndrome. Prognosis remains poor. Orv Hetil. 2019; 160(6): 228–234.
Two new records of Alpinia Roxb. (Zingiberaceae) in Sumatra, Indonesia and phylogenetic relationship to their allied species
Authors: Maulidah Rayfiqa , Fitri Suci Erta , Nurainas  , Syamsuardi  , Arbain Dayar
Published: February 2019

Alpinia is one genus of Zingiberaceae that is distributed throughout the tropical regions. Nine species of Alpinia have been recorded in Sumatra. In this article, we report 2 new record species for Sumatra, which are Alpinia submutica Roxb. and A. denticulata (Ridl.) Holttum. We also registered 3 sequences of them as new data in GenBank under accession number: MH087456, MH087457, and MH218561. Phylogenetic analysis using a molecular approach with their allied species in Sumatra is also presented.
ÖZ-ŞEFKAT ÖLÇEĞİ KISA FORMU’NUN TÜRKÇE UYARLAMASI: GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: YILDIRIM Musa , SARI Tuğba
Published: February 2019

Bu
araştırmada Öz-Şefkat Ölçeği Kısa Formu’unun Türkçe versiyonunun ergenler
üzerindeki psikometrik özelliklerini incelemek amaçlanmıştır. Bu amaçla 400’ü
ortaokul ve 400’ü lise öğrencisi olan 800 ergenden veri toplanmıştır. Ölçeği
psikometrik özelliklerini incelemek amacıyla yapı geçerliliği, ölçüt bağıntılı
geçerliliği, iç tutarlık katsayısı ve test-tekrar test güvenilirliği ele alınmıştır.
Elde edilen bulgulara göre orijinal formda bulunan 10. madde .30’un alında
faktör yükü olması sebebiyle ölçekten çıkarılmıştır. AFA sonucu ölçeğin tek
faktörlü bir yapı gösterdiği, bu faktörün iki alt bileşenden oluştuğu
görülmüştür. Yapılan DFA’da ölçeğin faktör yapısı doğrulanmıştır. Aynı zamanda
ergenlerin öz-şefkat puanlarıyla öznel iyi oluş puanları arasında orta düzey
pozitif bir ilişki saptanırken, öz-şefkat puanlarıyla kendine şefkat vermekten
korkma puanları arasında orta düzey negatif bir ilişki saptanmıştır. Ölçeğin iç
tutarlılık katsayısı ,75 olarak hesaplanmıştır. Son olarak 17 gün araya
uygulanan test-tekrar test ölçümleri arasında yüksek düzey bir ilişki olduğu
görülmüştür. Sonuç olarak Öz-Şefkat Ölçeği Kısa Formu'nun 11 maddeden ve tek boyuttan oluşan bir ölçek
olarak Türk ergenlerin öz-şefkat düzeyini ölçme konusunda geçerli ve güvenilir
bir ölçme aracı olduğu söylenebilir.
GÖRME ENGELLİ BİREYLERİN YABANCI DİL KELİME BİLGİLERİNİN GELİŞTİRİLMESİ: TASARIM TABANLI ARAŞTIRMA YAKLAŞIMI
Authors: GÜL Abdülmenaf , KAMALI ARSLANTAŞ Tuğba , YASAN Nehir , YURDAGÜL Cemil , YILDIRIM Zahide
Published: February 2019

Bu araştırmanın amacı görme
engelli bireylerin İngilizce kelimelerin doğru yazılışını öğrenmeleri için
erişilebilir web ve mobil öğrenme ortamının geliştirilmesi ve bu ortamların
görme engelliler için etkililiğinin araştırılmasıdır. Çalışmada tasarım tabanlı
araştırma yaklaşımı kullanılmış ve üç döngü uygulanmıştır. İlk iki döngüde web
sitesinin gelişim süreci tamamlanmış ve üçüncü döngüde mobil uygulama
geliştirilmiştir. Çalışmaya uygun örnekleme yöntemiyle seçilmiş 11 yetişkin
görme engelli katılmıştır. Veriler demografik bilgi formu, sesli düşünme
protokolleri ve gözlem formları aracılığıyla toplanmıştır. Bulgular, ortamların
pratik ve erişilebilir olduğunu, erişilebilirlik problemi olmayan bir ortamda
görme engellilerin öğrenmeye yönelik motivasyonlarının yüksek olduğunu ortaya
koymuştur. Görme engellilere yönelik geliştirilen tasarımlar görsel hiçbir
unsur içermemeli, içerik mimarisi hedef kitleye yönelik olmalı ve kullanıcılar
site içerisinde gitmek istedikleri yere kolay ulaşabilmelidirler.
OS MINICONTOS DE TERROR NA FORMAÇÃO DO LEITOR NA EDUCAÇÃO DE JOVENS E ADULTOS
Authors: Moraes Zenilda Roza , Silva Veronice Camargo , Sant' Anna Sita Mara Lopes
Published: February 2019

A presente pesquisa tem por objetivo refletir e apresentar como o gênero miniconto pode se constituir em instrumento para impulsionar o letramento literário, junto a estudantes da Educação de Jovens e Adultos - EJA, que frequentam o Ensino Fundamental. Para tanto, uma prática pedagógica foi desenvolvida, sob o olhar da pesquisa qualitativa e orientações da pesquisa-ação educacional. Deste modo, para embasar esta discussão e, sabendo-se da dificuldade em promover o interesse pela leitura neste contexto, com base nas demandas dos estudantes de EJA, pensou-se em um gênero que se constituísse na porta de entrada para outros contextos. Logo, os minicontos, mais especificamente, os minicontos de terror, foram selecionados por tratarem-se de narrativas curtas e criativas, além de oferecerem, aos alunos, o prazer que a escrita e a leitura podem proporcionar. Sendo assim, esta pesquisa adentrou nos estudos de Freire (1999, 2001, 2005) perpassando por Solé (1998), Todorov (2004), Gotlib (2006), Lois (2010), Cosson (2009), entre outros. Os resultados obtidos com este trabalho tornam-se relevantes, na medida em que a leitura de minicontos com a produção de “Terrorzines”, pelos estudantes, mostrou ser um bom incentivo à leitura e à escrita nesta modalidade de ensino, principalmente, por causar o envolvimento e o encantamento nos alunos, desde a maioria constituída por adolescentes e jovens, até os mais velhos. Palavras-chave: Educação de Jovens e Adultos; Minicontos; Letramento Literário; Fanzines.
Regionalidade e identidade em Um romancista apresenta sua terra, de Erico Verissimo
Authors: Marcon Daniele , Arendt João Claudio
Published: February 2019

Este artigo analisa a produção não-literária “Um romancista apresenta sua terra” – ensaio publicado originalmente em Rio Grande do Sul: terra e povo, pela Editora Globo, em 1964 – de autoria de Erico Verissimo. Tendo por base a definição de autores como Pozenato (2003), Cuche (2002), Woodward (2000), Oliven (2006) e outros, o objetivo consiste em verificar em que medida se encontram presentes, na fala de Verissimo, elementos que dizem respeito à região, à regionalidade e à identidade regional, discutindo o modo como o autor os dimensiona em seu texto.
A LEITURA DA LITERATURA NA EDUCAÇÃO E FORMAÇÃO DE JOVENS E ADULTOS: ENTRE O DIREITO E O DEVER
Authors: Dionísio Maria de Lourdes Da Trindade
Published: February 2019

A Declaração Europeia dos Direitos à Literacia inclui a leitura por prazer como um dos direitos dos cidadãos, sustentando-se nas avaliações internacionais de leitura que usam a leitura por prazer e literária também como indicador de proficiência. Neste sentido, tomamos, neste texto, o currículo português de Cursos de Educação e Formação de Jovens, como lugar de indagação do lugar da leitura literária na educação de jovens que viram a sua vida escolar reorientada dadas as suas trajetórias escolares de insucesso. Apesar do espaço concedido à leitura recreativa e resposta do leitor à obra literária, esta modalidade de leitura ocorre num quadro de dever e formatação dificilmente consonante com a formação de leitores assíduos e autónomos.
A(HÁ) LEITURA LITERÁRIA NA AULA DE LÍNGUA PORTUGUESA NA EDUCAÇÃO BÁSICA
Authors: Domingues Chirley , Jardim Fernanda Lima , Santana Dias Debus Eliane
Published: February 2019

O presente artigo apresenta reflexão sobre a leitura literária, aliando o sensível e o inteligível, a partir de ação didática pedagógica junto a estudantes do 9ª. Ano do Ensino Fundamental em 2018, com os livros As cores da escravidão, de Ieda de Oliveira, e A cor da ternura, de Geni Guimarães, contemporâneos e os clássicos conto Negrinha, de Monteiro Lobato e conto Lucinda, a mucama, de Joaquim Manuel de Macedo. A seleção das obras visou contemplar a exigência à Lei 10639/03, que define as Diretrizes Curriculares Nacionais para a Educação das Relações Étnico-raciais e para o Ensino de História e Cultura Afro-Brasileira e Africana na Educação Básica. Constatou-se por parte dos estudantes um envolvimento com o tema e com os títulos, independente do seu tempo histórico.
Unicystic Ameloblastoma in a Child Treated with a Combination of Conservative Surgery and Orthodontic Treatment: A Case Report
Authors: Takahashi Saori , Idaira Yayoi , Sato Toru , Asada Yoshinobu , Nakagawa Yoichi
Published: February 2019

Unicystic ameloblastoma (UAM) is a variant of intraosseous ameloblastoma that occurs as a single cystic cavity. This report describes a case of UAM of the mandible in a seven-year-old girl. The lesion radiographically mimicked a dentigerous cyst. Under the primary diagnosis of a dentigerous cyst, marsupialization was performed to erupt the first molar involved in the cystic lesion and to obtain a definitive diagnosis. The biopsy specimen revealed ameloblastoma. During careful observation, orthodontic treatment, which was performed to upright and promote the eruption of the first molar involved in the tumor, maintained the space needed for enucleation of the tumor. Finally, the second primary molar was extracted, and the lesion was enucleated at 3 years and 4 months after marsupialization. The results of the histological examination revealed UAM. Conclusively, the treatment course not only avoids a resection of the mandible but also induces eruption of the teeth involved in the tumor. Thus, the combination of conservative surgery and orthodontic treatment was effective in the management of UAM that mimics a dentigerous cyst.
La otredad Y LA DISCRIMINACIÓN DE GÉNEROS
Authors: Fandiño barros Yolanda alicia
Published: February 2019

Las desigualdades entre los sexos no se pueden rectificar si no se tienen en cuenta los presupuestos sociales que han impedido la igualdad, especialmente los efectos generados por la división femenina y masculina. La marginaciónde las mujeres, la valoración inferior de los trabajos por ellas desempeñados, su responsabilidad por el trabajo doméstico, su prolongado abandono del mercado laboral, su insuficiente formación profesional, la introyección de unmodelo único de femineidad y el hecho de que, en muchos casos, ellas mismas no reconozcan su estatus de víctimas de la discriminación, requiere una perspectiva de análisis que explique la existencia de la violencia, su persistencia y la complicidad de las propias víctimas en su perpetuación.
Protection Coatings for the Underwater Part of Ship’s Hull
Authors: Ivce Renato , Grubiša Matej , Mišković Darijo
Published: February 2019

In this article authors present a general consideration of the underwater part of ship’s hull protection by protective coatings, paying particular attention to antifouling paints. Following the presentation of the importance of ship’s hull maintenance and protection in order to make navigation safer and to keep the ship in operation for as long as possible, a summary is made of the main types of antifouling products used throughout the history up to the present time. As far back as a thousand years BC, people had developed techniques to protect objects from falling into disrepair and understood the importance of preserving construction materials in order to prolong their useful life and value. Marine industry has been developing day by day and attention is increasingly focused on the safety of ships and crews, as well as on the protection of marine environment. Tin-free self-polishing copolymer (SPC) and foul release technologies are currently applied, in addition to many alternative solutions being suggested. Modern approaches to effective environment-friendly antifouling systems and their performance are highlighted.
Towards Paperless Vessels: A Master’s Perspective
Authors: Brčić David , Žuškin Srđan
Published: February 2019

The transitional period of implementation of the Electronic Chart Display and Information System (ECDIS) expired on July 1st, 2018. As for this date onward, vessels of 3000 GT or more subject to the Safety of Life at Sea (SOLAS) Convention and engaged in international voyages, must be fitted with an official ECDIS system. The Convention furthermore requires mandatory possession of navigational equipment as an adequate back-up. In case that independent system is used for this purpose, there is no further obligation for a vessel to possess traditional paper navigational charts and it can be considered as paperless. Beside paper charts, this term also implies digital nautical publications and probably an electronic ship’s log in the foreseeable future. The interpretation of ECDIS differs considering particular rank of an Officer of the Watch (OOW) and its engagement towards the system. The system should be accepted by OOWs as true end-users. The proposed paper elaborates opinions and standpoints of decisive end-users towards the system, its role as a primary navigational means, and the fact that traditional navigation conduct is replaced by digital means. For this purpose a survey between OOWs was conducted focusing on their answers to respective questions. The sample size allowed for the observation of opinions over several years and the definition of the ECDIS acceptance level. Results are presented and discussed together with proposals of new activities which have to be carried out to improve the safety of navigation by the ECDIS system and its further development.
Impact of levonorgestrel intrauterine system on metabolic parameters
Authors: Singh Arushi , Mani Poonam , Prateek Shashi , Yadav Lalita , Gupta Eshna
Published: February 2019

Background: Hormonal contraceptive is suggested to affect parameters like body mass index, body weight, blood pressure (BP), blood sugar, lipid protein, and liver function test (LFT) but effect of LNG-IUS on those parameters is still uncertain. The aim of the present study was to study the effects of LNG-IUS on the metabolic parameters.Methods: Sixty women who opted for LNG-IUS for various indications were included in the study. Lipid profile, liver function tests (LFT), glucose levels [fasting and post prandial (PP)], and hemoglobin (Hb) were tested. Bimanual genital examination and transvaginal-ultrasonography was done prior to LNG-IUS insertion. Any problems observed were recorded. The subjects were re-evaluated after 6 and 9 months on their subsequent visits. Data were analyzed using paired “t” test. P value of <0.05 was considered statistically significant.Results: Mean age of the patients was 35.5±6.79 years. Maximum number 50 (83.3%) had abnormal uterine bleeding (ovulatory dysfunction, endometrial, iatrogenic, not yet classified) [AUB (OEIN)]. Mean pictorial blood loss assessment chart (PBAC) score of patients was 164.7±56.72 and mean Hb level 11.15±1.75g/dL. LNG-IUS showed no significant adverse effects on anthropometric parameters at 6- and 9-month follow-up. Significant change was seen in total cholesterol (TC), very low-density lipoprotein (VLDL) and high density lipoproteins (HDL) values at follow-up (p<0.0001).Conclusions: In conclusion, amongst Asian population, the LNG-IUS does not have any adverse effects on metabolic parameters, TGs, LDL and blood sugar levels.
Effect of obesity on the outcome of pregnancy in primigravida patients: an Iraqi experience
Authors: Mahmood Ban Dawood
Published: February 2019

Background: A parallel rise in the rate of obesity in women in reproductive age; and cesarean section as outcome of pregnancy is noticed in the last years in our society. It is unknown whether this dual rise is related or not. The impact is more evident on primigravida patients, so authors perform this study to assess the impact of obesity on the outcome of pregnancy in primigravida patients in a major obstetrics hospital.Methods: A prospective controlled study was conducted in Ibn Al-Balady obstetrics hospital. It included 121 primigravida patients who were divided into 3 groups according to WHO BMI categories: normal, overweight, and obese. The mode of delivery of these patients is recorded and was assessed in relation to BMI.Results: About 17% of the patients were obese and they needed more emergency CS as a mode of delivery than normal BMI patients (p<0.01). They also had longer second stage of labor (p<0.01) and delivered babies with higher birth weight that the normal group (p<0.05).Conclusions: Obesity constitutes a growing challenge on the outcome of pregnancy, duration of second stage of labor and baby birth weight in primigravida patients. Women who are getting pregnant for the first time should be advised to lower their BMI as a safety measure to avoid emergency cesarean section.
Skin disorders among elderly population without comorbidities: a hospital based study
Authors: Bains Pooja
Published: February 2019

Background: Aging is a permanent and progressive degenerative process which affects all organs of the body, including skin. There is a structural and physiologic transformation that arises as a result of intrinsic aging along with extrinsic damage which makes elderly skin more vulnerable to dermatologic disorders. In this study, we set out to determine the frequency and pattern of dermatological diseases in geriatric patients without chronic systemic illness and comorbidities like diabetes mellitus, hypertension and cardiac illness.

Methods: We enrolled 350 patients of the age 60 years and above who were not suffering from any chronic systemic disease for the study. Baseline information and clinical examination were done to make the diagnosis.

Results: The male: female ratio in our study was 1.14:1. The mean age of presentation was 68 year. The minimum age of patient was 60 years and maximum was 92 years. The most frequently encountered diseases in patients were eczematous dermatitis, fungal infections, scabies, xerosis and pruritus. Among eczemas, seborrheic dermatitis was the most common. Very few patients of solar lentigenes, skin tags and seborrheic keratosis came for dermatological consultation.

Conclusions: Eczemas were the most common dermatological disease in elderly in our study and pruritus was the most frequent complaint for which elderly visited skin Out Patient Department. Most of the diseases could possibly have been prevented.
Trombositoz saptanan çocuklarda klinik ve hematolojik profilin değerlendirilmesi
Authors: Oguz Melahat Melek , AÇOĞLU Esma Altınel
Published: February 2019

Amaç: Trombositoz çocuklarda beklenmeyen bir bulgu olarak
karşımıza çıkmakta ve daha çok reaktif trombositoz görülmektedir.Bu çalışmanın amacı çocuklarda
trombositozun; sıklığını, nedenlerini, düzelme süresini, trombosit
parametreleri ve enfeksiyon belirteçleri ile korelasyonunu belirlemektir.Gereç ve Yöntemler:Ekim 2016 ile Mayıs 2018 tarihleri
arasında Dr. Sami Ulus Kadın Doğum ve Çocuk Sağlığı ve Hastalıkları Eğitim ve
Araştırma Hastanesinde 6 ay 18 yaş arası trombositoz saptanan çocukların dahil
edildiği tanımlayıcı bir çalışmadır.Bulgular: Toplam 107564 hastanın %10,8 (n=11643)’inde
trombositoz saptandı. Bu hastaların %64,5’i 6ay-2 yaş arası çocuklardan
oluşuyordu. Ciddi trombositozun 141(%1,2) hastada geliştiği görüldü.En sık
ciddi trombositoz nedenleri sırası ile 80 hastada (%56,8) enfeksiyonlar, 21
hastada anemi (%14,9), 14 (%9,9) hastada ise otoimmun hastalıklar idi. Ciddi
trombositozların ortalama düzelme süresi 40,2±34 gün (3-210) olarak hesaplandı.
Hastaların hiçbirinde tromboembolik komplikasyon görülmedi. Trombosit sayısı
ile ortalama trombosit hacmi arasında
istatistiksel olarak anlamlı negatif korelasyon olduğu görüldü (p<0,05,
r=-0,214). Trombosit dağılım genişliği düzeyi ile trombosit sayısı arasında
korelasyon görülmedi (p=0,95). CRP düzeyi ile trombosit sayısı arasında istatistiksel
olarak anlamlı korelasyon saptanmadı (p=0,15).Trombosit sayısı ile
sedimantasyon hızı arasında ise istatistiksel olarak anlamlı korelasyon bulundu
(p<0,05, r=0,233). 

Sonuç: Çalışmamızda reaktif trombositozun sık rastlanılan
bir bulgu olduğunu ve bu büyük örneklemde primer trombositozun hiç görülmediğini, sekonder trombositozda altta yatan birçok farklı nedenin olabileceğini saptadık. Dolayısı
ile trombositozun ayırıcı tanısı ve yaklaşımı pediatri uzmanı tarafından
yapılmalıdır ve hematoloji bölümü konsültasyonu nadiren gerekmektedir. Özellikle
ciddi trombositozlarda gösterebildiğimiz enfeksiyon veya anemi yoksa kronik
inflamatuar hastalıkların altta yatan neden olabileceği unutulmamalıdır.
Yield and economics of pigeon pea based intercropping systems as influenced by different land configurations
Authors: Pawar S.U. , Garud H.S. , Asewar B.V. , Mirza I.A.B.
Published: February 2019

A field experiment was conducted at experimental farm of AICRP for Dry Land Agriculture, V.N.M.K.V., Parbhani during kharif season of 2015-16 and 2016-17 to study yield and economics of pigeon pea based intercropping systems as influenced by
different land configurations. Soil of experimental field was medium deep black with low in available nitrogen, medium in available phosphorus and high in available potassium. The experiment was laid out in split plot design with three main plot
treatments and four sub plot treatments. The main plot treatments were three land configurations as (L1) Broad bed furrow (BBF), (L2) Ridges and furrow and (L3) Flat bed method. Sub plot treatments were four intercropping systems i.e. (I1) pigeon pea
+ soybean (2:1), (I2) pigeon pea + greengram (2:1), (I3) pigeon pea + black gram (2:1) and (I4) pigeon pea + Cowpea (2:1). The highest pigeon pea equivalent yield and net returns of Rs. 67814 ha-1 were obtained with broad bed furrow (L1), which was
closely followed by treatment L2 (ridges and furrow) with net returns of Rs. 64095 ha-1. Among intercropping systems the highest pigeon pea equivalent yield and net returns of Rs. 68908 ha-1were obtained in pigeonpea+greeengram (2:1) intercropping
system and was followed by pigeonpea+blackgram and pigeonpea+soybean intercropping system.
Economics of turmeric cultivation in Erode district of Tamil Nadu
Authors: Kavitha V. , Chinnadurai M. , Angles S. , Sangeetha R.
Published: February 2019

Turmeric is the major spice crop in India. This paper attempts to estimate the cost and economic returns of turmeric cultivation among various size categories (marginal, small, semi medium, medium and large), of farmers in Erode district of
Tamil Nadu, which is one of the major turmeric growing region in India. The results of the study showed that of all the size categories, the economic returns realized by large farmers were comparatively higher..Besides ensuring reasonable price to
the farmers, the study suggested for value addition, like boiling, drying and grading of rhizomes in order to achieve maximum returns in turmeric cultivation.
Temporal changes in economics of pulses and their comparative advantage in Rajasthan
Authors: Sood Shivalika , Singh Hari , Soumya C.
Published: February 2019

The study aims to examine the temporal changes in economics of chickpea (gram), moong bean (green gram) and urd bean (black gram) production in western State of India i.e. Rajasthan. Study was entirely based on secondary data collected from
publication of Ministry of Agriculture, Govt. of India, New Delhi. The structural changes in cost of cultivation were analyzed by working out the difference in cost at two points of time (i.e. 2001-02 and 2013-14), along with relative share to total
cost. Study revealed that the average cost of cultivation of chickpea, moong bean and urd bean increased from Rs.9,941.66/ha, Rs.5,954.74/ha and Rs.7,849.31/ha in 2001-02 to Rs. 24,093.71/ha, Rs.17,793.53/ha and Rs. 21,346.36/ha in 2013-14.The net
income over total cost was highest for chickpea which is a major pulse crop of Rajasthan. During 2001-02, both moong bean and urd bean remained unprofitable over total cost. During 2013-14, chickpea and moong bean became profitable over total cost.
The level of profit was highest for chickpea followed by moong bean. Urd bean still remained unprofitable over total cost.
Growth parameters of acid lime (Citrus aurantifolia Swingle) cv. Kuliana lime
Authors: Mishra Subhrajyoti , Dash Dilip Kumar
Published: February 2019

An experiment was carried out to identify the effect of season on various leaf parameters of Kuliana lime during 2016-17 at Horticultural Research Station, Department of Fruit Science and Horticulture Technology, O.U.A.T., Bhubaneswar. The
rainy season recorded the maximum leaf fresh weight (0.39 g), leaf dry weight (0.18 g), leaf area (16.19 cm2) whereas spring season have greater production of chlorophyll-a (1.19 mg per g of FW), chlorophyll-b (0.61 mg per g of FW) and total
chlorophyll (1.81 mg per g of FW). Rainy season flush showed the maximum leaf area, leaf fresh weight and dry weight, due to the better availability of soil moisture and high relative humidity of atmosphere resulting in low transpiration losses which
perhaps favoured the better leaf growth. Though spring season have the most favourable climatic condition but carbohydrate in spring flush leaves were might utilized mainly to support reproductive growth hence there was reduction in the dry weight of
leaves.
Market integration of selected cotton markets in Haryana
Authors: Mahesh V. , Grover R.K. , Geetha R.S.
Published: February 2019

The present study aimed to paper the co-integration among the selected cotton markets in Haryana. The monthly data on prices of cotton were collected for the period from 2005-06 to 2016-17. The advanced econometric tools like ADF test,
Johansen co-integration test and Granger Causality test were used to study market integration. The price series of commodity namely cotton in selected markets showed the consequences of unit root and were stationary at first difference. The long run
equilibrium relationship among the selected markets indicated that these were integrated with each other. This implies that prices in domestic markets of Haryana move together in response to changes in the demand and supply and cost of a product.
Granger Causality test resulted Dabwali market as lead cotton market because it influenced the prices of most of selected cotton markets.
Morphometric and Meristic traits of four flatheads (family: Platycephalidae) occurring along the East coast of India
Authors: Jaiswar A. K. , . Vikas , Kumar Rajan , . Shashibhusan , Lakra W. S. , Vinay A.
Published: February 2019

Study on a meristic traits of Kumococius rodericensis Sorsogona tuberculata Platycephalus indicus and Rogadius serratus (family Platycephalidae), occurring along the East coast of India, was conducted to find easily differentiating traits.
The study was based on the samples collected from landing centers situated along the East coast of India, during February 2015 to March 2016. A total of thirty-one morphometric and meristic characters were measured, counted and subjected to
statistical analysis using software Statistica. Among eighteen morphometric measurements, five measurement (distance between upper and lower jaw, length of upper preopercular spine, snout length, maximum length of first dorsal spine, maximum length
of second dorsal spine) did not show difference when subjected to factor analysis. Varimax raw factor rotation on factor loading 0.7 were selected for scatterplot of canonical score among root 1 and root 2, which revealed existence of distinct group
of species. Number of gillrakers, spot on caudal fin, number of pored scale on lateral line and preopercular spine revealed significant variations among the species. The proportional measurements with their head length (HL) viz. Preorbital length:
head length (POL:HL), Inter orbital width: head length (IOW:HL), and maximum eye diameter: head length (MED:HL) also revealed significant difference among the species. The study revealed certain morphological characters those can easily identify the
flathead species.
Gross morphological studies on the sternum of crested serpent eagle (Spilornis cheela)
Authors: Choudhary O.P. , Kalita P.C. , Rajkhowa T.K. , Arya R.S. , Kalita A. , Doley P.J.
Published: February 2019

The present study was designed to elucidate the morphological characteristics of sternum of crested serpent eagle. The sternum was a thin, flat bone with a body, rostrum and keel. The body was quadrilateral plate with concave dorsal and
convex ventral surfaces and four borders. Numerous pneumatic foramina were present on the dorsal surface. The ventral surface presented a large, boat shaped keel along its median line. The cranial border was convex and thick and two pneumatic
foramina were present behind the cranial border on the ventral surface of sternum. The facets for coracoid bones were located just below the cranial border. The lateral border on either side presented six articular facets for sternal ribs. The
triangular pointed cranio-lateral process was observed at the junction of cranial and lateral border on either side. The caudal border was convex and caudo-lateral processes were absent. Two distinct oval foramina were seen near the caudal border.
The rostrum or sternal spine was smaller and located just below the cranial border of the body of the sternum. The sternum presented a well-developed triangular keel located along the midline of the ventral surface of the body of sternum.
In silico structural and phylogenetic analysis of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in domestic animals
Authors: Sahoo P.R. , Mishra S.R. , Mohapatra S. , Sahu Santoswini , Sahoo G. , Behera P.C.
Published: February 2019

This study has been able to determine the physiochemical properties, secondary and tertiary structure, and phylogenetic analysis of GAPDH among domestic animals under in silico platform. Eighteen nucleotide and protein sequence of GAPDH gene
of different mammalian species were retrieved from National Centre for Biotechnology information (NCBI). The percentage of identity and similarity was done by Basic Local Alignment Search Tool (BLAST), physiochemical properties were analyzed by
ExPASy”s ProtParam tool, the secondary and 3-D structure was predicted by GOR IV and Swiss modeling respectively. Phylogenetic analysis among the animals was done by Molecular Evolutionary Genetics Analysis. It was found that the percentage of
identity and similarity among all animals were almost more than 90%. The physiochemical analysis showed this protein is very stable, hydrophilic and intracytoplasmic in nature. The secondary structure analysis showed that GAPDH has more number of
random coil (49.85%) Extended strand (27.93%), alpha helix (22.22%) of the protein. The QMEAN Z score was found 0.33 under protein modeling which interfered that this protein is of comparable quality. The phylogenetic analysis of this gene showed
that the highest time of divergence occurred between sheep and common chimpanzee but least time of divergence observed between killer whale and dolphin. So it can be concluded that the GAPDH gene is highly conserved along all animal species.
Effect of TRIM28 on proliferation, apoptosis and histone H3K9 trimethylation in bovine fibroblasts
Authors: Ma Panpan , Man Xiaxia , Yang Shubao , Dong Xiaoqing , Su Liyan , Luan Weimin , Ma Xin
Published: February 2019

TRIM28 is a co-repressor, which interacts with HP1 proteins and chromatin repressive complexes leading to gene expression silencing. In this study, after we used Lipofectamine3000-mediating siRNA and restructured p EGFP-IRES2-TRIM28 to
transfect bovine fibroblasts, the expression levels of TRIM28, HP1BP3, DNMT, SETDB1, TP53, BAX, Bcl and SOD were detected by real-time polymerase chain reaction (PCR). In addition, the influence of p EGFP-IRES2-TRIM28 on histone H3K9me3 was also
observed. In the siRNA transfected group, TRIM28 was down-regulated (P less than 0.01), which inhibited cell proliferation and reduced the level of H3K9me3 expression. In the p EGFP-IRES2-TRIM28 transfected group, TRIM28 was over-expressed (P less
than 0.01), and the pro-apoptosis gene BAX was significantly decreased (P ess tahn 0.01), but there was no significant change in other genes. Our results demonstrate that TRIM28 plays an important role in bovine fibroblasts and might be a valuable
biomolecule for proliferation, apoptosis, and histone H3K9 trimethylation.
Beef colour defined based on pH in Holstein bull carcasses
Authors: Balci F. , Ardicli S. , Dincel D.
Published: February 2019

The present study was carried out on 510 Holstein-Fresian bulls and it aimed to evaluate the effects of season, age at slaughter and pH on meat colour characteristics. An additional aim of this analysis was to determine the impact of
environmental factors including season and slaughter age on meat pH. A cluster analysis applied to all the colour coordinates divided the samples into six groups according to their ultimate pH. L*, a*, b*, and C* values were significantly higher in
cattle slaughtered in the winter season. Moreover, a significant effect of age at slaughter on colour coordinates was found with the exception of a* value. Meat from bulls slaughtered at 16/17 months of age was characterized by brighter colour. Among
the pH groups, the highest value of L* was found in meat with pH less than 5.40, whereas, the highest a* and C* in pH 5.41-5.50. The present results may be useful and indicative for both beef industry and future studies on meat colour.
Babagan Bektaşilik ve Demokrat Parti
Authors: ÇIPLAK İsa Tolga , ÇEVİK Zeki
Published: February 2019

Osmanlı
tarihi içinde gelişen Heterodoks zümrelerden oluşan Bektaşi Tarikatı, 16.
yüzyıldan itibaren, Babagan ve Çelebilik olmak üzere ikiye ayrılmıştır. 1826'da
Yeniçerilerin kaldırılmasında ilişkisinden dolayı Babagan Bektaşilik
lağvedilmiş ve tekkelerine devlet el koymuştur. Fakat Babagan Bektaşilik resmi
olmayan bir durumda iken varlığını devam ettirmiştir. İttihat Terakki yönetimi
içerisine dahil olup yarı resmi bir hüviyete sahip olmuştur. Osmanlı
Devleti'nin hakimiyetinin sonlanması üzerine yeni kuruluna Türkiye Cumhuriyeti'nde
1925 yılı Tekkeler ve Zaviyeler kanunu gereğince diğer tüm tarikatlar gibi
Bektaşiliğin Babagan kolu da yasaklanmıştır. Makalenin konusunu işlediği dönem
Türkiye Cumuhuriyeti'nde Demokrat Partili yıllarda (1950-1960) yeniden tekke
geleneğine kavuşmak istemesi ve Demokrat Partili siyasetçilerin Bektaşiliğin
Babagan kolu ile olan ilişkisi ortaya konmuştur.