bluuebunny/crossref_metadata_2025 huggingface dataset:
FAMILY NURSING CARE USING NUTRITION EDUCATION INTERVENTION ON THE BODY MASS INDEX (BMI) IN SCHOOL-AGE CHILDREN WITH OBESITY IN RT 02 RW 07 KELURAHAN GROGOL KECAMATAN LIMO DEPOK CITY
Authors: Anggraini Nourmayansa Vidya , Pratiwi Devira Gite
Published: May 2024

Introduction: The incidence of obesity is continually increasing worldwide, including in both developed and developing countries. This condition can jeopardize health and increase the risk of disabilities in adults. Health education is defined as an effort to provide or improve the understanding, attitude, and actions taken by society in maintaining and improving their health. The purpose of this writing is to evaluate the effectiveness of health education interventions in reducing body mass index (BMI) in school-age children.
Method: The implementation method of the intervention is in the form of providing health education to school-age children. In providing health education about obesity in children by eating a diet and consuming healthy foods.
Results: The results of the two-week implementation showed that treated patients experienced a decrease in BMI of 0.60 SD, while discharged patients experienced a decrease in BMI of 0.59. It can be concluded that providing health education intervention to school-age children who are obese is an effective measure to reduce their body mass index
Conclusion: Therefore, as part of the management of obesity and overweight in school-age children, community nurses are expected to be able to implement health education.
Kompetensi Literasi Digital Mahasiswa Program Studi Pendidikan Geografi FKIP Universitas Lambung Mangkurat
Authors: Huda Nurul , Adyatma Sidharta , Hastuti Karunia Puji
Published: May 2024

The development of science and technology (IPTEK) which is very massive has a very broad influence on all aspects of human life. One of them is education and teaching that can facilitate the exchange of information so that it is not bound by space and time. This is of course very useful, especially for students, groups who always need information as reference material for their daily assignments. Therefore, students really need information literacy skills, to support the lectures they follow. There are several models used to measure a person's literacy ability, one of which is the Empowering 8 model, where this model was produced from a workshop conducted in Sri Lanka in 2004. The purpose of this study was to analyze the digital literacy competence of students of the geography education study program, FKIP Lambung Mangkurat University. This study uses a descriptive method with a quantitative approach. Based on the results of research that has been carried out, digital digital literacy students of geography education FKIP Lambung Mangkurat University are at a good or mastered level. Where from the respondents' answers, 17% were very dominant, 71% controlled, 11% did not master, and 1% did not master. Respondents who are very mastering, not mastering, and very not mastering are in the low category, respondents who are mastering are in the high category.
Strategi Keluarga Burhanudin Mohamad Diah Dalam Memperkuat Solidaritas Keluarga Di Negara Sosialis, 1959-1962
Authors: Wulandari Ayu
Published: May 2024

This article discusses the strategy of Burhanuddin Mohamad Diah's family as an ambassador's family in strengthening family solidarity when assigned to two socialist countries, namely Czechoslovakia and Hungary from 1959 to 1962. This article analyzes why family solidarity became so important for their lives in diplomatic posts, the channels and media used to strengthen this solidarity, and the role of women in it. This article was carried out using historical research methods which utilize various primary sources, ranging from ego documents, contemporary publications, oral history, to a number of official archives.  This article reveals that family solidarity at diplomatic posts was part of the comfort conditions for the B. M. Diah family. This is due to two factors, namely historical factors and family psychological factors. To build and strengthen family solidarity, the B. M. Diah’s family used a number of channels, spaces, and media, including the family's domestic space, arts, sports, and tourism. This article also reveals that the presence of family solidarity issues has encouraged the emergence of women's agency and activism in the B. M. Diah family. To be precise, B. M. Diah’s wife, Herawati Diah, was present as a driving force, leader, and decision maker in the family in order to strengthen their internal solidarity.
A Systematic Literature Review of Informal STEM Learning
Authors: Hussim Hairunnisa , Rosli Roslinda , Mohd Nor Nurul Aisya Zahira , Maat Siti Mistima , Mahmud Muhammad Sofwan , Iksan Zanaton , Rambely Azmin Sham , Mahmud Siti Nurdiyana , Halim Lilia , Osman Kamisah , Lay Ah Nam
Published: May 2024

Student learning outside the formal classroom is inextricably linked to informal learning environments. In many countries, most activities that employ informal learning prioritize the integration of science, technology, engineering, and mathematics (STEM) disciplines and have shown a positive impact on increasing students’ interest, self-efficacy, and awareness of the STEM field. Thus, this study aims to systematically review the activities reported in the relevant studies focusing on informal STEM learning for K–12. High-index journals published under SCOPUS and Web of Science databases were utilized using a predetermined search strategy and retrieved two research team members’ screened articles. Only empirical studies containing the terms “STEM education”, “summer camp”, and “informal learning” in the title, abstract, and keyword were included. Data were coded and organized into a matrix that was qualitatively assessed and categorized into themes. Based on the 25 studies reviewed, it was found that the integration of STEM disciplines in informal learning is notably varied. The characteristics of the STEM activities can be organized into seven themes: inquiry, focus on problems, design, cooperative learning, student-centred, hands-on, and 21st-century skills. Practice recommendations include a quality curriculum that aligns with informal STEM learning needs.
Development of Chemical Learning Electronic Module Based on Multiple Representation in The Redox Topic
Authors: Arfan Septian , Aznam Nurfina
Published: May 2024

The advent of the COVID-19 pandemic in 2020 significantly shifted educational paradigms, necessitating the adoption of online learning modalities. This study, rooted in the contextual changes brought by the pandemic, aimed to evaluate the effectiveness, quality, and impact of a Mixed Reality (MR) e-module on redox reaction topics in a high school setting. The research followed a 4D model (Define, Design, Develop, Disseminate) but was confined to the development phase.Conducted in a High School in Yogyakarta, Indonesia, this study involved 98 students (30 from grade 12 and 68 from grade 11), 3 teachers, and 2 validators. The research methodology included pre-tests and post-tests, alongside questionnaires to gather data. Descriptive statistical analysis was employed to process the assessments from validators, teachers, student responses, and test results.The field trial results indicated that the MR e-module for chemistry learning was deemed satisfactory and effective by the respondents. The analysis of the test of between-subject effect revealed no significant differences in interest and pre-test learning achievement between control and experimental groups. However, post-test results showed notable differences in interest and learning achievements, favoring the experimental group exposed to the MR e-module.The effectiveness of the MR e-module was quantified using partial eta squared calculations. The MR e-module contributed 25.7% effectively to both learning interest and achievement. When considered separately, the contribution was 2.7% for learning interest and 21.9% for learning achievement. These findings underscore the potential of MR e-modules as valuable educational tools, enhancing both student engagement and academic performance in online learning environments during the COVID-19 pandemic.
Beach Sand-derived Mesoporous Silica by Hydrothermal Process for Hydrocracking Waste Coconut Oil to Biofuel
Authors: Salamah Siti , Hanum Farrah Fadhillah , Trisunaryati Wega , Kartini Indriana , Purwono Suryo
Published: May 2024

Hydrocracking, a key process for converting waste coconut oil into biofuel, requires efficient catalysts. This study investigates the synthesis of mesoporous silica catalysts using a hydrothermal process. Dodecyl amine, sourced from beach sand, serves as a template. The hydrothermal synthesis involved durations (12, 15, 18, 21, and 24 hours) and dodecyl amine concentrations (0.25 M, 0.5 M, 0.1 M), conducted at 40 °C for 30 minutes. The synthesized catalysts were then characterized for their surface area, pore volume, and diameter. Among the synthesized samples, those treated for 15 hours displayed optimal total acidity at 0.88 mmol/g. The catalysts synthesized with a dodecyl amine concentration of 0.025 M exhibited superior characteristics, including a specific surface area of 233 m²/g, a pore volume of 0.47 cc/g, and an average pore diameter of 2.10 nm. These findings underscore the efficacy of mesoporous silica catalysts in hydrocracking, particularly in converting large hydrocarbon molecules into smaller, more valuable biofuel molecules. Comparative analysis with similar research highlights the significance of these findings in the field of sustainable energy. The optimal catalyst conditions yielded a liquid fraction of over 70% for 0.25 M dodecyl amine. This efficiency in converting waste coconut oil into biofuel signifies the potential of mesoporous silica catalysts in advancing environmentally friendly energy sources. This research contributes to the growing knowledge of renewable energy, offering promising avenues for developing sustainable and eco-friendly energy solutions.
Comparison of Air Contact And Distilled Water Distribution Method in The Conversion of Cao to Ca(OH)2 As A Precursor Hydroxyapatite Synthesis
Authors: Firnanelty Firnanelty , Abubakar Andi Nur Fitriani , Qurniawan Anas , Syam M. A.
Published: May 2024

Eggshells containing CaCO3 have potential as bioceramics for several tissue engineering applications. The content of CaCO3 converted into Ca(OH)2 can be used as a precursor to implant material. The purpose of the study was to compare two methods of converting CaO into Ca(OH)2 as the primary material for making hydroxyapatite. The method used is direct contact with air and dissolution with water. Hydroxyapatite synthesis using Ca(OH)2 is calcined from CaCO3 with a sintering temperature of 900 °C. The result of calcination is in the form of CaO. The stages of obtaining Ca(OH)2 by converting CaO using two methods, namely direct contact with air and dissolution with water. The XRD characterization results obtained that Ca(OH)2 results from direct contact with air show the formation of phase (portlandite), which is characterized by its presence at the highest typical 2θ angles = 18.18°, 28.68°, 34.30°, 47.40°, 50.92°, 54.16°, and 62.62°. The XRD Ca(OH)2 pattern with the distilled water distribution process shows the formation of a phase (portlandite) characterized by its presence at angles of 2θ = 18.18°, 28.68°, 34.30°, 47.40°, 50.92°, 54.16°, and 62.62 °. The results of FTIR Ca(OH)2 characterization of air contact and water dissolution showed strong O-H functional groups at wave numbers 3643 cm-1 and 3642 cm-1, C-O groups at 1487 cm-1 and 1483 cm-1. This suggests that both methods can convert CaO to Ca(OH)2, which synthesizes hydroxyapatite. The hydroxyapatite characterization results obtained have met the standard.
Optimization of Nitration of 3-Hydroxypyrazine-2-Carboxamide to 3-Hydroxy-6-Nitropyrazine-2-Carboxamide
Authors: Setyowati Widiastuti Agustina Eko , Ihsanawati Ihsanawati , Alni Anita
Published: May 2024

This study focuses on optimizing the synthesis of 3-hydroxy-6-nitropyrazine-2-carboxamide, a critical intermediate in producing various pyrazine-based pharmaceuticals. The compound is synthesized through the nitration of 3-hydroxypyrazine-2-carboxamide, employing sulfuric acid (H2SO4) and potassium nitrate (KNO3) as reagents. The research aimed to refine the synthesis process to enhance yield purity for pharmaceutical applications. The optimization entailed adjusting the reagents' composition and solvents, specifically the ratio of substrate to KNO3, the volume of H2SO4 used per gram of substrate, and the temperatures for both the reaction and product precipitation. Optimal results were observed at a substrate-to-KNO3 ratio of 1:2, with 12 mL of H2SO4 per gram of substrate. The reaction temperature was set at 50°, and precipitation occurred effectively at 0°C. This optimized method significantly improved the yield and purity of the compound. The process demonstrated excellent repeatability, with yields ranging from 77% to 80%, a considerable increase from the 48% yield reported in previous studies. The molecular structure of the synthesized compound was confirmed through comprehensive spectroscopic analyses, including 1H NMR, 13C NMR, and High-Resolution Electrospray Ionization Time-of-Flight Mass Spectrometry (HRESI-TOF-MS). This research represents a significant advancement in synthesizing 3-hydroxy-6-nitropyrazine-2-carboxamide, offering a more efficient and reliable method for producing this key pharmaceutical intermediate. The improved synthesis process ensures higher yields and maintains the purity required for pharmaceutical applications, thereby contributing to the efficient development of pyrazine-based drug compounds.
Fast-Track Legislation: The Transformation of Law-Making Under Joko Widodo’s Administration
Authors: Huda Ni’matul , Rishan Idul , Pratiwi Dian Kus
Published: May 2024

Since the end of 2019, the President and the House of Representatives had performed different legislative functions. Since the Law on the Commission Eradication Commission was amended, legislation had dramatically been transformed.  Several laws have been passed and amended quickly. This study discusses three legal issues. First, the conceptual limitation of fast-track legislation in Indonesia. Second, the rationale behind fast-track legislation under Joko Widodo's administration. Third, the impact of fast-track legislation under Joko Widodo's administration. In this socio-legal study, a qualitative analysis is conducted. This study has identified that (1) fast-track legislation in Indonesia can only be adopted through Perpu with all its exemptions and exceptions; (2) the transformation of law-making under Joko Widodo's administration is associated with political pragmatism, political personalization, the elimination of the opposition, and cartel parties; and (3) the transformation of law-making under Joko Widodo's administration is detrimental to the future of Indonesia's democracy. The transformation has degraded the quality of deliberation in law-making. Besides, it does not adhere to law-making procedures, resulting in elitist and conservative laws.
Sovereign Wealth Fund Development in Indonesia: Lessons Learned from Norway and Singapore
Authors: Gunawan Florencia Irena , Dini Alfatika Aunuriella , Sugarda Paripurna P
Published: May 2024

This study aimed to compare Sovereign Wealth Funds in Singapore, Norway, and Indonesia based on several categories: classification and objectives, nature, source of funds, management, implementation, funding policy, and regulatory framework. This study adopts the grounded theory approach for analysing and categorising the data. Earlier studies on SWF have been focused on the governance and operation of the SWF globally, with minimal attention paid to SWF in developing economies. The study shows that the Indonesia Investment Authority (INA), as a newly established SWF, encountered several issues related to applying good corporate governance. Therefore, comparing the more established SWF in Singapore and Norway is deemed significant in gaining valuable insight into INA's future. This circumstance is aimed at preserving the Government's trust by adding positive value to INA's business management and ensuring sustainability. The result gives assurance to potential investors of INA that INA’s legal basis is still valid and enforceable. Furthermore, an expanded INA governance framework is proposed as a practical contribution based on the results of other SWFs in Norway and Singapore. This framework is adjusted to suit INA's context and main objectives, including funding policy, supervisory institution, and transparency and accountability of the investment activities.
Word Box Intervention Revolutionizes Early Literacy Potential in Education
Authors: Nikmah Mafrukhatun , Destiana Evie
Published: May 2024

his study investigates the efficacy of utilizing the "Word Box" media to enhance beginning reading skills among 5-6-year-old children in a preschool setting. Through a classroom action research (PTK) approach involving 12 participants, the study demonstrates a significant improvement in beginning reading proficiency from 17% in the pre-cycle to 83% in cycle II. The findings underscore the effectiveness of the intervention in improving early literacy skills and highlight its implications for teacher pedagogy and classroom management in preschool education.

 
Highlight:

Notable improvement: "Word Box" enhances beginning reading in preschoolers.
Effective method: Innovative teaching fosters early literacy development.
Pedagogical impact: Improves teacher skills and classroom management in preschool education.

 
Keyword: Beginning reading, Preschool education, Classroom action research, Word Box media, Literacy development
MUDIG transforms global vocational education by enhancing engagement
Authors: Olvyya Amaydhi , Hasanah Fitria Nur
Published: May 2024

This research introduces MUDIG (Mobile Understanding Digital Graphic) learning media, designed to enhance class X students' comprehension of Graphic Design at Diponegoro Vocational School, Sidoarjo. Utilizing the Research and Development (R&D) methodology with the Analysis, Design, Development, Implementation, and Evaluation (ADDIE) model, the study aimed to address the lack of engaging learning materials in vocational education. Results from a small-scale trial showed positive student responses, with an average assessment of 86.6%, alongside high suitability ratings from expert validation. Student feedback emphasized increased interest, motivation, and understanding of the subject matter. These findings underscore the potential of innovative media like MUDIG to improve teaching and learning outcomes in vocational education, suggesting avenues for further exploration and implementation in broader classroom contexts.
 
Highlight:

MUDIG enhances Graphic Design learning in vocational education.
Students respond positively, showing increased interest and comprehension.
R&D methodology, ADDIE model ensure structured development and evaluation.

 
Keyword: MUDIG, Graphic Design, Vocational Education, R&D Methodology, ADDIE Model
Enhancing Student Collaboration in Science Education Through Outdoor Learning Transformation
Authors: Khoirot Mil’Al , Setiyawati Enik
Published: May 2024

This study explores the efficacy of implementing outdoor learning to enhance student collaboration in fourth-grade science education at SD Muhammadiyah 1 Candi Sidoarjo, addressing a gap in research regarding its application in primary school science education. Using a descriptive qualitative approach with observation, interviews, and documentation, data analysis followed the Miles and Huberman model. Results indicate successful implementation of outdoor learning, fostering collaboration among students, particularly in accepting responsibility, assisting peers, and respecting opinions. Variations in collaboration effectiveness were noted between student groups. Findings suggest that carefully planned outdoor learning activities can create an engaging learning environment, improving student collaboration and overall learning outcomes in primary school science education.
 
Highlight: 

Outdoor learning in primary science: Enhancing student collaboration and engagement.
Qualitative approach: Investigating student perspectives on outdoor education.
Effective peer interactions: Fostering teamwork in outdoor learning environments.

Keyword: Outdoor learning, Student collaboration, Primary school, Science education, Qualitative research
PENGEMBANGAN BY PRODUCT AYAM MENJADI ABON TIALE BERBAHAN DASAR HATI AYAM DAN IKAN LELE UNTUK MAKANAN TAMBAHAN ANAK BALITA
Authors: Dalimunthe Nathasa Khalida , Saleh Asep Jalaludin , Artika Putri Ayu
Published: May 2024

Latar Belakang: Makanan tambahan dapat menambah nilai gizi pangan yang akan dikonsumsi anak. Makanan tambahan yang ada dinilai kurang optimal karena sumber bahan dasarnya dari karbohidrat, sedangkan pada anak usia balita mengalami peningkatan kebutuhan akan protein untuk tumbuh kembang. Sumber protein yang memiliki bioavailibilitas yang tinggi berasal dari hewani. Tujuan: Tujuan penelitian untuk mengembangkan produk Abon sebagai makanan tambahan untuk balita berbahan dasar hati ayam dan ikan lele dalam bentuk Abon Tiale. Metode: Desain penelitian adalah experimental murni dengan Rancangan Acak Lengkap (RAL) dua kali pengulangan. Faktor perlakuan dalam pembuatan Abon Tiale yaitu perbandingan hati ayam dan daging ikan lele. Terdapat 4 taraf perlakuan yaitu F1 = 200:0; F2 = 150:50; F3 = 100:100; F4 = 50:150. Uji hedonik digunakan untuk melihat tingkat kesukaan dari 30 panelis  semi terlatih terhadap Abon Tiale. Analisis data yang digunakan yaitu deskriptif dan inferensia (One Way ANOVA serta uji Duncan) dengan tingkat kepercayaan 95%. Hasil: Empat formulasi Abon Tiale berbahan dasar hati ayam dan daging ikan lele berbeda pada setiap atribut warna (p=0,000), rasa (p=0,005), aroma (p=0,001), tekstur (p=0,000). Formula terbaik berdasarkan hasil penilaian panelis yaitu formula F3 (50:150). Kesimpulan: Pemanfaatan by product seperti hati ayam berpotensi untuk menjadi makanan tambahan anak balita dalam rangka pencegahan masalah gizi. Penambahan daging ikan lele pada abon dapat meningkatkan daya terima dari sisi warna, aroma, rasa, dan tekstur.
HUBUNGAN ASUPAN ZAT GIZI TERHADAP KADAR GLUKOSA DARAH, KOLESTEROL DAN ASAM URAT, PADA PEGAWAI KANTOR DI PROVINSI RIAU
Authors: Roziana Roziana , Gultom Yessi Marlina , Alza Yessi , Arsil Yuliana
Published: May 2024

Latar belakang : Pola makan pegawai negeri sipil diketahui tinggi guloksa, purin dan asam lemak hewani. Makanan tinggi glukosa berisiko meningkatkan kadar gula darah, begitupun makanan tinggi purin berisiko untuk meningkatkan kadar asam urat. Masyarakat perkotaan cenderung tinggi mengkonsumsi makanan yang tinggi akan karbohidrat, protein dan lemak sehingga dapat meningkatkan kadar gula darah, kolesterol dan asam urat. Tujuan : untuk mengetahui hubungan asupan zat gizi energi, karbohidrat, protein, lemak, serat dengan kadar gula darah kolesterol, dan asam urat. Metode : jenis survei yang bersifat analitik dengan desain penelitian crosssectional, dengan sampel penelitian sebanyak 50 orang yang diambil dengan cara Purposive Sampling. Analisis uji statistic yang digunakan adalah uji Chi-Square dengan derajat kepercayaan 95 %. Hasil : Hubungan antara asupan zat energi, karbohidrat, protein, lemak, serat dengan kadar gula darah adalah (p>0,05) artinya tidak ada hubungan yang signifikan antara asupan zat gizi dengan kadar gula darah. Hubungan antara asupan zat energi, karbohidrat, protein, lemak, serat dengan kadar kolesterol adalah (p>0,05) artinya tidak ada hubungan yang signifikan antara asupan zat gizi dengan kadar kolesterol. Hubungan antara asupan zat energi, karbohidrat, protein, lemak, serat, dengan kadar asam urat adalah (p>0,05) artinya tidak ada hubungan yang signifikan antara asupan zat gizi dengan kadar asam urat. Kesimpulan : Uji statistic menunjukkan tidak ada hubungan yang bermakna antara asupan zat energi, karbohidrat, protein, lemak, serat dengan kadar gula darah, kolesterol, dan asam urat.
PANGAN FUNGSIONAL MIE CELOR SEBAGAI ALTERNATIF JAJANAN PADAT GIZI UNTUK ANAK USIA SEKOLAH
Authors: Hervidea Radella Hervidea , Dalimunthe Nathasa Khalida
Published: May 2024

Latar belakang: Anak pada usia sekolah adalah salah satu fase kehidupan yang memerlukan asupan gizi cukup dan seimbang untuk mendukung pertumbuhan, perkembangannya serta beraktivitas fisik. Salah satu upaya yang dapat dilakukan untuk memenuhi kebutuhan gizinya yaitu dengan mengkonsumsi makanan yang bergizi tinggi seperti yang terbuat dari rumput laut jenis Gracillaria sp. dan daun kelor. Pengembangan produk olahan berbahan dasar Gracillaria sp. dan kelor berpotensi dalam meningkatkan kandungan gizi pada jajanan anak sekolah karena memiliki kandungan gizi yang tinggi dan mudah ditemukan. Tujuan: Penelitian ini dianggap penting untuk menemukan formula terbaru dalam menghasilkan pangan fungsional yaitu mie celor (Gracillaria dan kelor) yang tinggi gizi baik makro, mikro dan antioksidan. Metode: Penelitian ini dilaksanakan pada Juni sampai Desember 2023. Pembuatan produk Mie Celor dengan 5 formulasi (F1,F2,F3,F4 dan F5) serta uji organoleptik akan dilaksanakan di Laboratorium Kuliner Universitas Mitra Indonesia dan analisis proksimat, zat gizi mikro dan kandungan antioksidan akan dilaksanakan di Laboratorium Politeknik Negeri Lampung. Data yang dikumpulkan meliputi data yang diuji secara objektif yaitu data uji organoleptik, uji proksimat, zat gizi mikro, dan  analisis antioksidan. Uji hipotesis dilakukan menggunakan uji Anova menggunakan program SPSS dengan tingkat signifikansi yaitu p<0.05. Hasil: Berdasarkan hasil uji organoleptik oleh 30 panelis pada  penerimaan secara keseluruhan F5 adalah formulasi dengan nilai tertinggi yaitu 3.77 (p-value <0.453). Uji analisis proksimat pada F5 didapatkan hasil kandungan air, abu,protein dan karbohidrat berbeda nyata (p-value <0,05) dibanding dengan F1. Hasil analisis aktivitas antioksidan F5 didapatkan nilai IC50 4534.01 µG/mL. Kesimpulan: Penambahan rumput laut dan kelor meningkatkan nilai penerimaan secara keseluruhan, merubah kadungan air, abu, protein, karbohidrat, lemak dan meningkatkan kandungan antioksidan pada mie celor.
POLA MAKAN DAN AKTIVITAS FISIK MAHASISWA FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS KRISTEN SATYA WACANA SELAMA PANDEMI COVID-19
Authors: Davidson Sarah Melati , Tampubolon Rifatolistia , Situmorang Agnes Rouli
Published: May 2024

Latar belakang: Pandemi COVID-19 yang terjadi di seluruh dunia membuat kegiatan masyarakat menjadi terbatas karena adanya peraturan yang diterbitkan pemerintah untuk melakukan pembatasan sosial secara besar-besaran. Pembatasan sosial tersebut memberikan dampak pada sistem belajar yang dialihkan menjadi sistem online. Kegiatan-kegiatan mahasiswa yang beralih menjadi onlinedapat berdampak pada pola makan dan aktivitas fisik. Tujuan: untuk mengetahui gambaran pola makan dan aktivitas fisik mahasiswa kesehatan Universitas Kristen Satya Wacana selama pandemi COVID-19. Metode: Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan pendekatan cross sectional. Data didapatkan dari pengisian kuesioner FFQ dan GPAQ yangdiisi secara mandiri oleh responden. Kuesioner diisi oleh 86 orang responden. Hasil: responden mendapatkan sumber karbohidrat dari nasi dengan frekuensi 17,94 ± 4,12, sumber protein hewani dari daging sapi dengan frekuensi 1,08 ± 0,83, daging ayam dengan frekuensi 6,28 ± 6,22, dan telur ayam dengan frekuensi 4,69 ± 4,65. Konsumsi sayur dan buah-buahan pada mahasiswa cenderung rendah serta konsumsi minuman dan jajanan pada mahasiswa cenderung rendah. Namun, mahasiswa banyak mengonsumsi martabak manis dengan frekuensi 1,21 ± 0,82. Sebanyak 50% mahasiswa kesehatan Universitas Kristen Satya Wacana memiliki aktivitas fisik dengan intensitas rendah dan sebanyak 50 orang responden memiliki kegiatan sedentari kategori tinggi. Simpulan: pola makan mahasiswa kesehatan Universitas Kristen Satya Wacana masih belum sesuai dengan pedoman gizi seimbang dan mengalami penurunan aktivitas fisik.
Antecedent-Focused Emotion Regulation Strategies in Obesity: An EEG study on Distraction and Reappraisal
Authors: Fernandes Joana , Fernandes Carina , Ferreira-Santos Fernando , Torres Sandra
Published: May 2024

Background/ Objectives: Impairments in emotion regulation (ER) have been reported in obesity (OB), with most studies showing greater use of maladaptive strategies while others show difficulties implementing adaptative strategies. A complementary tool to self-report measures for studying ER is event-related potentials (ERP), concretely the late positive potential (LPP), which allows to understand the time-course of ER processes. This study analyzed behavioral and neural correlates of adaptative ER strategies, distraction and reappraisal, and when they start being applied, in OB individuals and healthy controls (HC).
Subjects/ Methods: Twenty-eight participants with OB (BMI > 30) and 23 HC were recruited. Participants performed an ER task, while EEG was recorded.
Results: Results showed that OB individuals (vs. HC) presented greater LPP amplitudes for distraction and reappraisal, at 500-700ms. In the OB group, reappraisal reduced LPP earlier (300-1300ms) than distraction (1500-1700ms).
Conclusions: These findings highlight ER difficulties early in the emotion-generative process in OB, specifically pertaining to attention deployment, independently of the presence of binge eating symptoms.
Advancing Dengue Virus Surveillance: A Rapid Multiplexed One-Step RT-PCR assay for Comprehensive Diagnosis and Serotype Identification
Authors: Gangwar Mayank , Shukla Alka , Singh Digvijay , Singh Ashish , Prakash Pradyot , Nath Gopal
Published: May 2024

Managing dengue effectively is crucial due to four virus serotypes causing varying infection severities. Dengue fever has becoming more prevalent. Cases of haemorrhagic fever place a significant cost on society and its survivors. This study analyses prevalent serotypes during an endemic situation for severity and community transmission.
During a dengue outbreak in 2022, 514 samples were included in this study, and various diagnostic tests were employed. Dengue viral NS1 antigen gene, IgM antibody detection were executed using ELISA tests, while dengue RT-PCR for molecular confirmation using single-tube dengue multiplex RT-PCR assays to detect the presence of viral RNA and determine the infecting serotype. Data suggested that 108 were highly positive for dengue viral NS1Ag. Sensitivity and specificity of single-tube RT-PCR for dengue were found to be 79.41 and 100% respectively. Among the samples tested with the dengue Multiplex Real-Time PCR assay, 50.60% (n=41) were positive with DENV-2 being the most prevalent serotype followed by DENV-1 (32.10%, n=26) and DENV-3 (12.3%, n= 10).
Dengue fever is a global health challenge, especially in India. Serotyping identifies circulating serotypes. RT-PCR multiplexing assay can be a promising molecular diagnostic method, proving highly sensitive, specific, and rapid. It holds great promise for swift and reliable dengue virus detection and serotyping, enhancing future identification of cases for vaccine development.
WITHDRAWN: Simulation Analysis of Electron Diffusion in Circular Semiconductor Attached With Gold Nanoparticle
Authors: wang junli
Published: May 2024

The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Effect of Mediterranean diet adherence on all-cause and cause-specific mortality of vertebral compression fractures: results from the NHANES database cohort study
Authors: zhang Longyu , Zhao Yi , Xu Jiao , Yin Shi , Wang Qiang , Jia Zhiwei , Ren Jingpei , Mu Xiaohong
Published: May 2024

Background: Vertebral compression fractures (VCFs) is a common fragility fracture with high mortality worldwide. The management and prevention of VCFs start with a proper nutrition. The Mediterranean diet (MD) is rich in balanced nutrients and has been shown to be beneficial for several chronic diseases. However, the association of adherence to Mediterranean diet (aMED) and outcome of VCFs patients remains unclear. This study aims to explore the association between adherence to Mediterranean diet (aMED) and all-cause and Cardiovascular diseases-cause (CVD-cause) mortality in VCFs patients.
Methods: In present study, patients aged ≥40 years old and with the VCFs measurement were extracted from the National Health and Nutrition Examination Survey (NHANES) 2013-2014. The bone mineral density (BMD) dual-energy X-ray absorptiometry (DXA) was used to diagnose VCFs. The weighted univariable and multivariable COX proportional hazards regression models were utilized to explore the moderating effect of aMED and the risk of mortality in VCFs patients, and were described as hazard ratios (HRs) and 95% confidence intervals (CIs). Subgroup analyses based on different complications were further assessed the association.
Results: A total of 2,730 patients were included. Until 12 December 2019, 218 (7.99%) deaths were documented. VCFs was related to the high risk of all-cause mortality (HR= 1.75, 95%CI: 1.13-2.73) and CVD-cause mortality (HR=2.35, 95%CI: 1.12-4.91). Compared to the patients without VCFs and with aMED score ≥6, patients with VCFs and aMED score <6 has a higher risk of all-cause (HR=2.27, 95%CI: 1.25-4.13) and CVD-cause mortality (HR=4.25, 95%CI: 1.64-11.06). Our study also suggested that there was a moderating effect of aMED on the mortality of VCFs patients (all-cause mortality: HR: 1.36, 95%CI: 0.71-2.61; CVD-mortality: HR: 1.53, 95%CI: 0.46-5.12), especially in patients with dyslipidemia (HR: 2.49, 95%CI: 1.29-4.80), CVD (HR: 3.48, 95%CI: 1.56-7.74) and Chronic kidney disease(CKD) (HR: 3.64, 95%CI: 1.50-8.78).
Conclusion: Greater adherence to the MD may have a moderating effect on the risk of all-cause and CVD-cause mortality in VCFs patients. Our research further supports the importance of the MD as a potentially healthy eating pattern.
The design of a smart polymeric nanocarrier system linked to Polyamidoamine dendrimer (PAMAM) in fluorouracil drug delivery
Authors: Kaamyabi Sharif
Published: May 2024

In this study, a new platform has been developed and characterized to address the challenges in cancer treatment using the commonly employed anticancer drug 5-Fluorouracil (5FU). Polyamidoamine dendrimer (PAMAM) was grafted to poly (N-isopropyl acrylamide), a temperature-sensitive polymer, and the drug was encapsulated with ethylene glycol dimethyl acrylate (EGDMA). The performance of the synthesized nanocarrier was evaluated using techniques like nuclear magnetic resonance spectroscopy (1HNMR), Fourier transform spectroscopy (FT-IR), ultraviolet-visible spectrometer (UV-vis), and thermal analysis (TGA-DTA). Scanning electron microscope (SEM) images revealed that the nanocarrier maintained a spherical shape ranging from 45–65 nm even after drug attachment. The results demonstrate a significant enhancement in the release profile behavior of this system compared to previous ones. Despite its temperature sensitivity, the system exhibited increased half-life, improved bioavailability at lower concentrations, and reduced toxicity, thereby enhancing the drug's efficacy and improving its application in drug delivery systems.
Changes in renal function in CHB patients with Peg-IFN combined with nucleos(t)ide analogs
Authors: Zhao Jinhua , Wu Lili , Yang Xiaoan , Gao Zhiliang , Deng Hong
Published: May 2024

Background
There is limited research comparing the renal safety of entecavir (ETV) and tenofovir disoproxil fumarate (TDF) when used with pegylated interferon (pegIFN) in patients with chronic hepatitis B (CHB). Here, renal function changes in CHB patients were compared between treated with pegyIFN combined with ETV or TDF.
Methods
713 patients with the combination therapy of pegIFN and ETV or TDF were included in a matched analysis comparing outcomes between cured (HBsAg < 0.05IU/mL) and uncured patients, while 123 patients received pegIFN alone as a control group for comparison with the pegIFN-ETV and pegIFN-TDF treatment groups. The primary outcome was the change in renal function. Patients were categorized into stage 1 or stage 2 based on baseline estimated glomerular filtration rate (eGFR) < 90 ml/min/m².
Results
In total, 125 CHB patients were matched 1:1 in both the cured and the uncured group. Renal function in the stage 1 and stage 2 groups showed a decreasing trend at 48 weeks after an initial increase. After matching, the study included patients in the pegIFN-ETV or pegIFN-TDF group (n = 208, respectively), and 104 patients in the pegIFN-alone group. No significant difference in the impact of the three drug regimens on renal function at 48 weeks was found (P = 0.955). A logistic regression model using age and baseline eGFR predicted the AUC of eGFR status at 48 weeks to be 0.851 (95% CI, 0.807, 0.895).
Conclusions
After 48 weeks of combined treatment in patients with CHB, neither pegIFN-TDF nor pegIFN-ETV led to an increase in renal injury.
Frequency of Ponticulus Posticus in Cone-Beam Computed Tomography
Authors: Rojas Patricio Andrés Meléndez , Rodriguez Macarena , Silva Camila , Zamora Javiera , Niklander Sven , Villalobos María
Published: May 2024

Purpose: The objective of this work is to know the frequency of PP in a subpopulation of the city of Viña del Mar, Chile. What is the frequency of PP in cone beam tomography (CBCT)?
Methods: This was a descriptive observational study of 722 CBCT scans. The presence or absence of PP was analyzed, and the Cederberg and Stubbs classification was used to determine the corresponding degree of ossification. Statistical analysis was performed to establish the relationship with age and gender using the Chi-square test. This study was approved by the Scientific and Ethics Committee of the Faculty of Dentistry, Andrés Bello University.
Results: The frequency of PP was of 48.07%, with bilateral PP being more common (61.96%). In terms of laterality and degree of ossification, grade 2 of ossification predominated on both sides (right: 17.87%, left: 17.72%). A slight predominance of PP was observed in males (52.3%) compared to females (45.73%), but this was not statistically significant (p > 0.05). With respect to the frequency of PP and age range, it was observed in 50.75% of images of individuals over 41 years of age, 47.31% in those under 20 years of age, and 43.66% in those between 21 and 40 years of age, but these differences were not statistically significant (p > 0.05).
Conclusion: The presence of PP is common in the population and is not associated with age or gender.
Prolonged cancer treatment may affect return to work on gynecologic cancer
Authors: Tani Yoshinori , Nakamura Keiichiro , Sugihara Hanako , Shirakawa Shinsuke , Matsuoka Hirofumi , Ida Naoyuki , Haraga Junko , Ogawa Chikako , Nagao Shoji , Masuyama Hisashi
Published: May 2024

Background: Gynecologic cancer (GC) is one of the most common malignancies in working-age women. This study aimed to investigate the period of sick leave (PSL) after GC treatment in Japan.
Methods: We investigated the correlation between PSL, treatment methods, and adverseeffects after GC treatment in 207 cancer survivors who returned to work at the same workplace. We distributed questionnaires to patients with cancer who visited Okayama University (more than one year post-treatment, <65 years old), extracted information from their medical records, and used the Mann–Whitney U-test and logistic regression analysis to determine the impact on PSL.
Results: Surgery plus more than six courses of chemotherapy (Cx) led to a significantly longer PSL than surgery without lymph node dissection (LND)alone, surgery with LND, surgery plus less than six courses of Cx, and radiotherapy alone (all p<0.001). GC survivors who experienced adverse effects after treatment had a significantly delayed time to PSL (p=0.045). In univariate and multivariate analyses, patients who received surgery plus more than six courses of Cx were most involved in long PSL than other factors (both p<0.001).
Conclusions: Patients with GC requiring long-term treatment required the most time to return to work.
Natural Rubber Latex Modified Concrete for Resilient Construction
Authors: MATHEW LIJI ANNA , Joseph Glory
Published: May 2024

Major infrastructure projects often demand high performance concrete with properties such as high flexural strength, toughness, resistance to abrasion and high durability. Polymer modified concrete facilitates to enhance the flexural strength and serviceability of concrete structures. In this study, the potential of Natural Rubber Latex (NRL), a natural polymer, as an alternative to synthetic latex for enhancing the performance characteristics of concrete is explored. Natural rubber latex is added in concrete to incorporate dry rubber content of 0.5–2% by weight of cement in the mixture composition. A comparison of latex modified concrete is made with polypropylene and basalt fibre-reinforced concrete and the hybrid effect of fibre and latex in concrete. Results indicated a significant increase in energy absorption capacity (up to 231%) due to impact loading and reduction in wear in addition to the improvement in flexural strength with the modification of concrete using latex. Reduced chloride ion permeability and water absorption of latex modified concrete is indicative of highly durable concrete. Microstructure investigation confirmed a dense matrix for the NRL modified concrete making it a promising solution for structures in aggressive environments and pavement construction.
Prospective observational study to describe the clinical variability of equine asthma phenotypes
Authors: Meiseberg Lia Kristin , Delarocque Julien , de Buhr Nicole , Ohnesorge Bernhard
Published: May 2024

Background:
Equine asthma is a common, non-infectious, chronic lung disease that affects up to 80% of the horse population. Diagnostic guidelines rely on history, clinical presentation, and neutrophil count in bronchoalveolar lavage fluid. However, strict phenotyping and identification of subclinical asthmatic horses can be challenging. The aim of this study was to describe the equine asthma phenotypes (mild, moderate, and severe asthma) in a clinical population and identify the variables and examination steps with best discriminative potential. A standardised examination protocol was used, which included clinical examinations, blood work, airway endoscopy with bronchoalveolar lavage fluid analysis, arterial blood gas analysis and radiography.
Results:
Out of 26 horses, four were diagnosed with mild (subclinical), seven with moderate, and seven with severe asthma. Eight horses served as controls with no evidence of respiratory disease. Cough with history of coughing was the strongest clinical variable in phenotype differentiation. All horses with mild asthma were distinguishable from healthy individuals by mast cell counts in bronchoalveolar lavage cytology only. Moderate and severe asthmatic horses were characterised by clinical symptoms and neutrophil counts. Regardless of data subsets used in algorithmic evaluation of classification trees, a differentiation of three phenotypes without neutrophil and mast cell counts in bronchoalveolar lavage cytology is not sufficient for clinical diagnostics. Factor analysis revealed an increasing clinical variability with disease severity and an overlapping of clinical presentations between the phenotypes.
Conclusions:
Equine asthma phenotypes are clinically variable with overlapping symptom severities. History of coughing and bronchoalveolar lavage cytology are the strongest discriminant parameters. Mild asthma is differentiated by bronchoalveolar lavage cytology only. The results indicate that medical history, clinical examination and bronchoalveolar lavage cytology are indispensable steps to diagnose equine asthma and that a comparably exact diagnosis cannot be achieved by relying on alternative examinations or surrogate variables. An absence of single symptoms does not necessarily indicate an absence of advanced disease, while the presence of symptoms indicates disease severity. Diagnosing equine asthma should rely on medical history, clinical examination, and endoscopy including bronchoalveolar lavage cytology. Screenings of inconspicuous horses with bronchoalveolar lavage can aid in diagnosing subclinical affected animals.
Shifting Tides: A Survey Analysis of Urologists' Evolving Attitudes and Practice Patterns in Focal Therapy for Prostate Cancer
Authors: Koehler Jason , Lazarovich Alon , Tayebi Shima , Viswanath Vijay , George Arvin , Hsu Wei-Wen , Sidana Abhinav
Published: May 2024

Purpose: Focal therapy (FT) is emerging as an alternative option to radical treatments for prostate cancer (CaP). The purpose of this study is to assess urologists’ current perceptions and utilization of FT.
Methods: A 22-item questionnaire was emailed to members of the American Urological Association. Multivariate logistic regression analysis was used to identify predictors of FT utilization. Results were also compared to a previous survey performed in 2017.
Results: A total of 264 responses were recorded. Less than half (115/264, 43.6%) of respondents utilize FT in their practice; among them, 42% perform FT on more than 10 patients/year. Common reasons for avoiding FT were diverse and included: lack of experience (51.8%), belief that CaP is multifocal (46.0%), and a lack of infrastructure (43.1%). The most commonly utilized modality for FT was high-intensity focused ultrasound (63.4%) followed by cryoablation (47.3%). Preferred patients selected for FT were primarily unilateral/anterior only Gleason Grade Group 2 (95/110, 86.4%). A fellowship training in urologic oncology (OR=2.86, p=0.008) and seeing more than 10 CaP patients per month (OR=2.46, p=0.002) were associated with greater utilization of FT. Most respondents (85.4%) cited better imaging methods as a factor that has increased FT utilization. Compared to a previous survey, a higher number of respondents (43% vs. 24%) utilize FT in their practice and more respondents believe in the "index lesion theory".
Conclusions: Less than half of the respondents utilize FT in their practice. Fellowship training in urologic oncology and a higher volume of CaP patients were correlated with FT utilization. As urologists gain more experience the trend of further utilization of FT for CaP may rise.