bluuebunny/crossref_metadata_2025 huggingface dataset:
Fabrication of Hydrophilic Organosilicon Coatings and Study of Their Resistance to Factors Accompanying Corona Discharge
Authors: Emelyanenko К. А. , Ryabkova О. А. , Denman N.
Published: November 2024

Modern power industry widely uses high-voltage overhead lines to transport electricity, which are characterized by problems of corona discharge and leakage currents, especially in rain and snow conditions. One approach to solve these problems is to create protective coatings that can reduce corona in adverse weather conditions. This paper presents a study of a hydrophilic organosilicon coating based on aminopropyltriethoxysilane and PEG-400 for aluminum wires. Studies conducted to assess the resistance of the coating to prolonged contact with water, UV radiation and an ozone-saturated atmosphere have shown that the hydrophilicity of the coating increases under effect of these factors, which improves its anti-corona properties. Thus, durability under operating conditions open prospects for use of the developed coating in the energy sector.
Atmospheric-Resistant Organosilicate Coatings with Improved Water Resistance
Authors: Krasilnikova L. N. , Khamidulin Ya. A. , Voshchikov V. I. , Vasilieva E. D. , Kychkin A. K. , Nguyen Chi Van , Nikolaev A. M. , Gorshkova Yu. E. , Shilova O. A.
Published: November 2024

Currently, glass fiber and epoxy resin-based composites are successfully used in the manufacture of various structural elements. Such structures often have to be operated in extreme conditions, both in the Far North and the tropics, which have a destructive effect on the material, contributing to the degradation of its properties. In this case, water resistance is an important characteristic of the materials. One of the ways of protection is the use of organosilicate coatings (OSC), obtained on the basis of organosilicon varnishes and highly dispersed hydrosilicates. This article presents the results of laboratory studies and field tests carried out in areas with very cold, as well as tropical savannah and subequatorial climates, of composite and metallic materials protected by OSC. The objects of the studies were coatings based on a binder - polidimethylphenylsiloxane, modified to improve weather resistance, primarily moisture resistance, with polidimethylsiloxane and epoxy resin. The dependence of water absorption, wetting angle, and hardness of OSC on the composition of the polymer binders was traced; the optimal concentrations of these precursors were identified. The results of field tests have shown that the developed OSC retain their water-repellent properties during long-term exposure in different climatic conditions, which confirms their suitability for protecting various materials, both in the tropics and in the Far North.
Control of Technological Parameters of Detonation Spraying for Obtaining Coatings Based on Titanium Dioxide with Specified Wetting Properties
Authors: Sirota V. V. , Savotchenko S. E. , Strokova V. V. , Podgorony D. S. , Zaytsev S. V. , Churikov A. S. , Kovaleva M. G.
Published: November 2024

The study of the water-repellent properties of the surface of a metal-ceramic coating for protective purposes based on dioxide titanium is carried out. It is shown that the water-repellent properties of the coating surface can be effectively changed by varying the technological parameters of spraying. During the production of coatings, such technological parameters as the distance from the substrate to the barrel of the detonation gun and the speed of its passage are changed. A pattern is identified that connects the technological parameters of detonation coating spraying and the contact angle of wetting. It is established that the dependence of the contact angle on the spraying distance obeys a parabolic law under certain conditions. The parameters of phenomenological equation that adequately describes the observed parabolic dependence are calculated. The optimal values of the technological parameters of detonation spraying necessary to achieve maximum hydrophobicity of the produced coatings have been determined.
АНАЛІЗ ВІДОМИХ МЕТОДІВ ТА ІНФОРМАЦІЙНИХ ТЕХНОЛОГІЙ РОЗПІЗНАВАННЯ ДИСФУНКЦІЇ КАРДІОСТИМУЛЯТОРА
Authors: ГРИЩУК Ілля , ГОВОРУЩЕНКО Тетяна , КИСІЛЬ Тетяна , ГНАТЧУК Єлизавета
Published: November 2024

Пацієнтів із серцево-судинними захворюваннями, особливо з аритміями, необхідно спостерігати у режимі реального часу, щоб мінімізувати виникнення критичних станів, що можуть призвести до смерті. Діагностика серцево-судинних захворювань в тому числі й аритмій, також потребує постійного довготривалого моніторингу. Найкращим рішенням є постійний моніторинг частоти серцевих скорочень з використанням автоматизованих або автоматичних інструментів та технологій для моніторингу параметрів роботи серця.
На коректність роботи кардіостимулятора може впливати величезна кількість факторів: вік та зношеність кардіостимулятора, електромагнітні перешкоди, проблеми з вбудованим програмним забезпеченням кардіостимулятора, некоректне або погане підключення електродів кардіостимулятора, механічні ушкодження кардіостимулятора, низький заряд батареї кардіостимулятора, вплив високовольтного обладнання, біатрофія, викликана певними медичними процедурами, електростатичні розряди у навколишньому середовищі, інтерференція від бездротових пристроїв, екстремальні температури. Усі ці ризики повинні бути мінімізовані.
Нерозпізнані дисфункції кардіостимулятора можуть призвести до серйозних ускладнень в пацієнтів, тому виявлення проблем у ранній стадії є критично важливим для запобігання таких ускладнень.
На сьогодні актуальною є задача розроблення мультимодальної інформаційної технології, яка поєднуватиме декілька шляхів розпізнавання дисфункцій кардіостимулятора з метою забезпечення високої надійності їх виявлення – опрацьовуватиме діагностичні дані та повідомлення з кардіостимулятора, виконуватиме моніторинг роботи серця, зчитування електрокардіограми та аналіз серцевого ритму, застосуватиме спеціальні алгоритми для виявлення аномальних ситуацій, які можуть свідчити про дисфункцію кардіостимулятора, використовуватиме сенсори, що здатні виявляти зміни в серцевій діяльності, та автоматично повідомлятиме про будь-які виявлені дисфункції.
Як показав проведений аналіз, відомі на сьогодні рішення не розв’язують задачі розроблення мультимодальної інформаційної технології, яка поєднує всі шляхи розпізнавання дисфункцій кардіостимулятора з метою забезпечення високої надійності їх виявлення.
APPROACH TO DETECTION OF ANOMALOUS NETWORK TRAFFIC USING LOF AND HBOS ALGORITHMS
Authors: PETLIAK Nataliia , BILETSKYI Kostiantyn , ZASTAVNA Yana
Published: November 2024

The article is devoted to the problem of detecting anomalies in modern computer networks, which is one of the main threats to cyber security. With the development of Internet technologies, the number of devices and the volume of network traffic are constantly increasing, which leads to an increase in the risk of various cyber threats, such as DDoS attacks, zero-day attacks, and exploitation of protocol vulnerabilities. Abnormal network traffic can result from malicious activity and technical malfunctions, such as configuration errors or hardware failures. Specialised algorithms and methods of analysing large volumes of data are used to detect such threats. The paper considers the main methods of detecting anomalies in network traffic, including classical approaches and modern deep and machine learning methods. Special attention is paid to the efficiency of using methods based on convolutional neural networks, long-term memory and their combinations to detect anomalies. An analysis of the disadvantages and advantages of various approaches to detecting anomalous traffic, such as high computational requirements and the complexity of setting up models, is performed. Still, their effectiveness in analysing large volumes of data is noted. One of the main methods used for anomaly analysis is the local outlier algorithm, which compares the density of objects with their neighbours, allowing for the detection of anomalies in regional segments of the data. Another method is histogram-based outlier estimation, which is faster and more efficient using one-dimensional histograms for each variable. The work also explores the application of unsupervised machine learning methods, which allows for analysing network traffic in real time without the need for prior labelling of data. The article also considers the prospects of further testing the proposed methods in real networks. The combined use of LOF and HBOS balances anomaly detection accuracy and data processing speed, essential to ensure continuous system operation in high-load networks. The implementation of similar solutions in actual conditions requires further research, particularly regarding optimising the use of computing resources and adapting methods to the specific conditions of the network environment. Thus, the paper presents a thorough analysis of modern approaches to detecting anomalies in network traffic and substantiates the feasibility of their application in actual conditions to increase the effectiveness of cyber security.
AUDIT AND QUALITY CONTROL OF FOOD PRODUCTS IN EU COUNTRIES AND THE WORLD
Authors: ANTONENKO Аrtem , TOLOK Galina , BROVENKO Tetiana , BIRIUKOVA Oleksandra , RATUSHENKO Antonina , GORKUN Artem
Published: November 2024

The article examines regulatory legal acts and other documents and literary sources regarding state control of food safety and quality in Great Britain, Germany, France, the USA and Japan. The health of every nation largely depends on the quality and safety of food products. In any country, at the state level, requirements for product safety and quality are regulated and their compliance is ensured. One of the methods of such provision is state control. The article analyzes the practices of controlling the quality and safety of food products in the USA, Germany, France, Great Britain and Japan. It was revealed that there are both common and special rules in the practice of controlling the quality and safety of food products in the studied countries. In all countries, control over the quality and safety of food products is carried out by state bodies. In all countries, during control, special attention is paid to the reliability of product labeling. Improper labeling entails banning the sale of products, removal from circulation or destruction of particularly dangerous products, and even criminal liability in France and the USA. The main responsibility for dangerous food products in all countries is borne by the manufacturers or suppliers of the products who put them into circulation. In the USA and Japan, information about the presence of allergens in a food product must be included in the labeling. In the USA, in order for the manufacturer's products to be able to be supplied for a government order, the enterprise must implement a quality management system in accordance with the requirements of ISO 9001, and in Japan, in order to obtain a permit for the manufacture of food products, it is necessary to prove that proper sanitary and hygienic control is ensured by implementing HACCP system. In Germany, Great Britain, and Japan, quality and safety control is entrusted to local self-government bodies. In Germany, there is a product safety monitoring program throughout the territory, which makes it possible to monitor the appearance of dangerous products on the market, as well as to check the effectiveness of the established MPC of dangerous substances. The presence of "passports" for ready-made food products is checked only in France, although such a document is mandatory in EU countries. In France and Japan, exceptional importance is attached to the education of schoolchildren on food safety issues.
ПОРІВНЯЛЬНИЙ АНАЛІЗ МОДЕЛЕЙ АТАК НА ІНФОРМАЦІЙНУ БЕЗПЕКУ
Authors: ТІТОВА Віра , КЛЬОЦ Юрій , ЛАКОЦЕНІН Захар , ШЛАПАК Олександра , ТРОЦ Віталій
Published: November 2024

В даній статті проведено аналіз існуючих на сьогоднішній день способів моделювання загроз інформаційної безпеки, зокрема атак.
На основі проведеного аналізу можна зробити висновки, що усі існуючі моделі атак мають низку загальних недоліків, а тому існує необхідність удосконалення та розробки нових методик визначення актуальних загроз безпеці інформації, що виключають існуючі недоліки.
Підвищити якість моделювання актуальних моделей загроз інформаційної безпеки можливо  за рахунок визначення необхідних та достатніх показників та автоматизації процесу для виключення гіпотетичних помилок експертів.
МЕТОД ПРОГНОЗУВАННЯ МЕТРОЛОГІЧНИХ РИЗИКІВ ЯКОСТІ ПРОДУКЦІЇ
Authors: АРТЕМУК Ольга-Соломія , МИКИЙЧУК Микола
Published: November 2024

У статті розглядається застосування моделей прогнозування часових рядів для оцінки метрологічного ризику якості продукції на етапі  виготовлення продукції. Метрологічний ризик, який визначається через такі параметри, як значущість ризику, ймовірність виникнення та ймовірність виявлення, виступає як часовий ряд, що потребує точного прогнозування для управління ризиками в виробничому процесі. Для прогнозування МР в даній роботі використовуються шість моделей: Facebook Prophet, Statsmodels SARIMAX, Forecaster Recursive, Forecaster Direct, LGBMRegressor та Linear Regression. Кожна з моделей була досліджена на даних, що охоплюють період з 1 січня 2023 року по 24 листопада 2024 року. Вхідні дані були поділені на два набори: для навчання нейронної мережі та для порівняння прогнозованих значень із дійсними. Результати дослідження показали, що найточніші прогнози метрологічного ризику забезпечуються моделями Facebook Prophet та Statsmodels SARIMAX, які продемонстрували найкращі результати за основними метриками точності, зокрема MAE, RMSE, MAPE та R2. Крім того, порівняння результатів прогнозування візуально продемонструвало, що ці моделі здатні точніше відображати реальні зміни в рівні ризику у часі. Логістична регресія та інші моделі, як показали результати, мають обмежену ефективність у прогнозуванні метрологічного ризику. Враховуючи результати дослідження, можна стверджувати, що використання моделей часових рядів є ефективним підходом для прогнозування метрологічних ризиків у виробничих процесах. Це дозволяє не лише знижувати ймовірність виникнення непередбачуваних ситуацій, а й оптимізувати контроль за якістю продукції. В подальшому планується удосконалення моделей для зниження рівня похибок, підвищення їх адаптивності до змінних умов виробництва та інтеграцію моделей прогнозування у системи прийняття рішень.
ТЕОРЕТИКО-ПРАКТИЧНІ АСПЕКТИ УПРАВЛІННЯ КАДРОВИМ ПОТЕНЦІАЛОМ АГРАРНОГО ПІДПРИЄМСТВА У СУЧАСНИХ УМОВАХ
Authors: ОСТАХОВ Олександр , ЛАРІНА Тетяна , ГАЛИЦЬКИЙ Олександр
Published: November 2024

Стаття присвячена дослідженню теоретико-практичних аспектів управління кадровим потенціалом аграрних підприємств у сучасних умовах.
Доведено, що кадровий потенціал аграрного підприємства є важливим стратегічним ресурсом, від якого залежить ефективність діяльності компанії. Його складовими є професійні знання, досвід, навички, а також особисті якості працівників, їхня мотивація та здатність до розвитку.
З’ясовано, що у сучасних умовах управління кадровим потенціалом аграрного підприємства вимагає застосування системного, стратегічного та інноваційного підходів.
Встановлено, що ефективна система управління кадровим потенціалом в аграрному секторі включає планування кадрових потреб, навчання та розвиток працівників, мотивацію, оцінку їхньої діяльності, а також підтримку сезонних працівників і формування кадрового резерву.
Обґрунтовано, що сучасне управління кадровим потенціалом аграрного підприємства має базуватися на комплексному підході, що поєднує планування, розвиток, мотивацію, оцінку та технологічні інновації. Це дозволяє підвищувати ефективність виробництва, знижувати плинність кадрів та адаптуватися до швидкозмінних умов ринку.
ІННОВАЦІЇ ЯК ДРАЙВЕР КОНКУРЕНТОСПРОМОЖНОСТІ АГРОПРОМИСЛОВИХ ПІДПРИЄМСТВ НА ГЛОБАЛЬНОМУ РИНКУ
Authors: РОМАНЮК Олександр
Published: November 2024

Глобалізація, зміцнення інтеграційних процесів та сучасні виклики, що стоять перед світовою продовольчою системою, наголошують на важливості підвищення конкурентоспроможності продукції агропромислового комплексу та сільського господарства в цілому. Сучасний розвиток глобального ринку ставить перед агропромисловими підприємствами нові виклики, зокрема необхідність підвищення конкурентоспроможності, адаптації до змінного зовнішнього середовища та забезпечення стійкого економічного зростання. У цьому контексті інновації відіграють ключову роль, виступаючи драйвером, що сприяє оптимізації виробничих процесів, підвищенню якості продукції та ефективному використанню ресурсів. Інноваційна діяльність дозволяє агропромисловим підприємствам не лише задовольняти сучасні запити споживачів, але й прогнозувати майбутні тенденції, формуючи конкурентні переваги на світовому ринку. Особливого значення набувають технологічні, організаційні, цифрові та екологічні інновації, які дають змогу підприємствам забезпечувати сталий розвиток і відповідність міжнародним стандартам. Конкурентоспроможність сільськогосподарської продукції стає дедалі значимішою, оскільки продовольство грає значної ролі у сфері. Зазначено що конкуренція змушує реалізувати резерви виробництва, застосовувати нові технології, розширювати можливості використання вже наявних ресурсів та технологій, саме тому вона вважається основою розвитку економіки та двигуном прогресу. Дослідження проблеми конкурентоспроможності проводиться з урахуванням забезпечення продовольчої незалежності від коливань на світовому ринку, що пов'язано з різними економічними та соціальними умовами.  Визначено, що на глобальному ринку конкурентоспроможність агропромислових підприємств залежить від їхньої здатності впроваджувати інновації, адаптуватися до змін і створювати продукти, які відповідають сучасним запитам споживачів. Завдяки прихильності до інновацій, співпраці та цілісному підходу, сільськогосподарський сектор може впоратися з проблемами і вступити в нову еру сталого процвітання.
ВИКОРИСТАННЯ ДІДЖИТАЛ-ТЕХНОЛОГІЙ В УПРАВЛІННІ КАДРОВИМ ПОТЕНЦІАЛОМ ПІДПРИЄМСТВА
Authors: ДЯЧКОВ Дмитро , САЗОНОВА Тетяна , ВОВКОВІНСЬКИЙ Юрій
Published: November 2024

У статті акцентовано увагу сучасні тенденції цифровізації функціоналу HR-діяльності сучасних суб’єктів господарювання, які спрямовані на розширення спектрів імплементації досягнень цифровізації в управління кадровим потенціалом за різними напрямами роботи. Узагальнено основні тренди діджиталізації HR-менеджменту підприємств. Відмічено, що зазначені тренди стосуються не тільки класичних завдань кадрового менеджменту, але й для таких сучасних функцій кадрового менеджменту як  управління гібридними командами, відслідковування ефективності діяльності територіально розосереджених груп, перевірка навичок працівників за допомогою сучасних засобів та технологій ШІ, моніторинг настрою співробітників тощо. Проведений аналіз тенденцій, напрямів, інструментів цифровізації управління людськими ресурсами дав змогу виявити основні зміни, що відбуваються в HR-менеджменті під впливом діджитал-трансформації серед яких: автоматизація функцій управління людськими ресурсами, розвиток нових форм зайнятості і моделей HR-управління, застосування цифрового аналізу даних і технологій штучного інтелекту, формування цифрової культури інновацій і змін, поява нових професійних навичок і компетенцій співробітників. Окреслено ключові переваги застосування цифрового HR-менеджменту на сучасних підприємствах, а також певні наслідки запровадженням інструментів і методів цифрового управління кадровим потенціалом підприємства.
Безпосередні та віддалені результати модифікованої операції Росса
Authors: Romaniuk O. M.
Published: November 2024

The aim – to present our experience with a modified Ross procedure (RP) – total aortic root reinforcement (TARR)  – which significantly reduces intraoperative risks and improves long-term outcomes.Materials and methods. The immediate and long-term results of 312 RPs performed between 2005 and 2023 were analyzed and compared, including 202 surgeries using the TARR technique and 110 with the standard technique. Statistical methods included regression-correlation analysis, prognostic modeling with stepwise binary logistic regression, ROC analysis, t-tests, and the information value (IV) test.Results. Hospital mortality was 2.2 %, and overall mortality was 3.2 %. Survival rates were: 100 % at 1 year, 98.6 % at 10 years (97.2–100; 95 % confidence interval, CI), and 97.8 % at 20 years (95.8–99.7; 95 % CI). Hospital and overall mortality were significantly lower in the TARR group compared to the standard method – 1 % versus 4.5 % (p = 0.007) and 1 % versus 7.3 % (p = 0.0013), respectively. Predictors of mortality included patient age (younger than 5.75 months), preoperative mechanical ventilation, Ross – Konno procedure, and use of the standard RP. The follow-up period averaged 79.8 ± 52 months (3-208 months) and was completed for 288 (95.3 %) patients. The systolic gradient on the autograft in the early postoperative period significantly decreased from a preoperative value of 57.0 mm Hg [36; 72] (6; 177) to 7 mm Hg [4; 11] (3; 19) (p = 0.0023). In the long-term period, it was 8 mm Hg [5; 13] (2; 59). Neo-aortic insufficiency (neoAI) was observed in the long-term period as follows: grade 0-1 in 263 (91.3 %) patients, grade 2 in 23 (8 %) patients, and grade 3 or higher in 2 (0.7 %) patients. Predictors of neoAI development included older age at surgery, use of the standard technique, and preoperative aortic insufficiency. There were 3 (1 %) reoperations on the autograft, with freedom from autograft reoperation rates of 100 %, 98.3 %, and 96.2 % at 5, 10, and 15 years post-surgery, respectively. The TARR technique reduced the risks of hospital and long-term mortality (p = 0.0027; OR 13.7 [7.56; 24.97]) as well as neo-aortic insufficiency and the need for reoperation (p = 0.002, odds ratio 4 [1.020; 19.506]).Conclusions. The modified Ross procedure effectively addresses aortic valve pathology in patients of various ages, ensuring high survival and quality of life. The TARR modification provides low surgical-stage risks, optimal hemodynamic properties of the pulmonary valve as an aortic valve prosthesis, the autograft’s capacity for growth while maintaining function, and minimal risks of autograft dysfunction.
Mid-term outcome and quality of life after Bentall procedure: single-center experience
Authors: Stetsyuk I. O. , Stetsiuk L. R. , Todurov B. M. , Mokryk I. Yu. , Zaviiskyi V. I. , Nechai I. P. , Demyanchuk V. B. , Zelenchuk O. V.
Published: November 2024

The aim – to evaluate the mid-term results and quality of life of patients who underwent Bentall procedure.Materials and methods. The research included 55 patients who underwent planned surgical treatment at the Heart Institute of Ministry of Health of Ukraine from 2015 to 2023. The mean age of the 55 patients (53 (96.36 %) males), who underwent the Bentall procedure (composite graft replacement of the aortic root), was 52.36 ± 1.56 years. We analyzed basic characteristics of the patients, intraoperative and postoperative data. The quality of life was assessed before and in the mid-term period after operations by the Medical Outcomes Study Short Form 36 (MOS SF-36) questionnaire.Results. An average duration of the follow-up period was (3.61 ± 0.28) (СІ 3.05–4.16) years ranging from 1.0 to 9.0 years. Overall, in-hospital mortality and 30-day mortality was 1.89 % (n = 1). The only case of death was caused by the acute respiratory distress syndrome. The 5-year survival rate was 94.61 ± 3.10 % for all patients. It is reasonable to say that all 3 cases of death were due to a non-cardiac cause, i.e. stroke, malignancy and acute abdomen. The average duration of the operations was 244.48 ± 7.67 minutes, the total duration of artificial blood circulation was 138.73 ± 6.47 minutes, aorta clamping time – 95.82 ± 4.79 minutes. The mean duration of hospital staying was 16.98 ± 0.91 days, intensive care unit – 4.84 ± 0.33 days. The number of patients extubated up to 8 hours after surgery was 41 (74.55 %) patients. The operation significantly improved parameters of the quality of life. Conclusions. Patients after Bentall procedure have low overall in-hospital mortality and 30-day mortality (1 (1.89 %)). The 5-year survival rate was 94.61 ± 3.10 %. All three case of death during follow-up period were due to non-cardiac causes. Excellent mid-term results prove that Bentall procedure must be a routine surgery for patients with aortic root aneurysm, mixed aortic valve pathology and anatomically altered aortic valve leaflets. The operation significantly improved quality of life of patients in all domains.
Клінічна характеристика пацієнтів похилого віку з ураженням основного стовбура лівої коронарної артерії
Authors: Maksakov A. O. , Khokhlov A. V.
Published: November 2024

​The​ ​aim – to analyze the clinical features of elderly patients with left main coronary artery disease (CAD).Materials and methods. This prospective cohort study included 124 patients with left main CAD aged 60 to 75 years (elderly age group) and 100 control patients aged 44 to 60 who underwent coronary angiography between September 2021 and July 2024. Demographic data, history of coronary artery disease and associated diseases, laboratory test results, results of echocardiography and coronary angiography were collected and analyzed. Results. Elderly patients were characterized by a significantly higher (p = 0.030) frequency of myocardial infarction, as well as higher (p = 0.035) frequency of previous percutaneous coronary interventions compared to middle-aged patients. Elderly patients also had a significantly higher functional class according to NYHA compared to middle-aged patients (p = 0.0005), significantly higher rate of arterial hypertension (p = 0.012), diabetes mellitus (p = 0.033), cerebrovascular disease (p = 0.009), chronic kidney disease (p = 0.011) and anemia (p = 0.044), compared to middle-aged patients. Moreover, elderly patients were characterized by significantly higher creatinine, LDL and glucose levels.Conclusions. Elderly patients with left main CAD were characterized by a more severe course of the disease, more severe coronary lesions, and a higher frequency of concomitant cardiac and non-cardiac diseases compared to middle-aged patients.
Функція зовнішнього дихання та дифузійна здатність легень у пацієнтів із різними формами легеневої гіпертензії
Authors: Progonov S. O. , Torbas O. O. , Kushnir S. M. , Sirenko Yu. M. , Radchenko G. D.
Published: November 2024

The aim – to compare pulmonary function test (PFT) results and diffusion capacity of the lungs for carbon monoxide (DLCO) in patients with various forms of pulmonary arterial hypertension (PAH), chronic thromboembolic pulmonary hypertension (CTEPH) and healthy individuals; to establish correlations between PFT, DLCO and parameters used to stratify the risk of death in pulmonary hypertension (PH).Materials and methods. 74 patients were included: 18 with idiopathic PAH (IPAH), 15 with PAH associated with congenital heart defects (PAH-CHD), 21 with CTEPH and 20 healthy persons (control group). All participants underwent an assessment of PFT (vital capacity (VC), forced vital capacity (FVC), forced expiratory volume during one second (FEV1), peak expiratory velocity (PEV), maximum expiratory flow (MEF) 75, MEF-50, MEF-25) and measurement of DLCO. For all PH patients the standard examinations were provided, including N-terminal brain natriuretic peptide (NT-proBNP) assessment and right heart catheterization. Results. Patients of all PH groups had significantly lower parameters of PFT and DLCO, compared to the control group. The most pronounced and reliable decrease in PFT was observed among patients with PAH-CHD. The lowest DLCO was observed in CTEPH group. PH patients with DLCO < 64 %, compared with DLCO ≥ 64 %, had significantly lower distance of the 6-minute walk test (6MWT) (p = 0.014), TAPSE (р = 0.015), SpO2 during pulse oximetry and direct measurement (p = 0.023 and 0.032, respectively), hemoglobin level (p = 0.031). They had a significantly higher level of NT-proBNP (p = 0.012) and they were somewhat older (p = 0.053). DLCO < 64 % correlated with hemoglobin level (r = –0.31, p = 0.022), 6MWT distance (r = –0.35, p = 0.012), SpO2 (r = –0.29, p = 0.036), TAPSE (r = –0.34, p = 0.012) and NT-proBNP (r = 0.27, p = 0.048). Independent predictors of reduced DLCO were hemoglobin level (β = 0.95, CI 0.90-0.99), SpO2 (β = 0.75, CI 0.58-0.95) and TAPSE (β = 0.75, CI 0.63-0.91).Conclusions. Parameters of PFT and DLCO were significantly lower in patients of all PH groups compared to the healthy individuals. Patients with PAH-CHD had significantly worse PFT parameters. In the general population of patients with PH, PFT indicators, which characterize inspiratory capabilities, were independently correlated with the area of ​​the right atrium. The reduced DLCO (< 64 %) correlated with the level of hemoglobin, SpO2 and indicators of the patient functional state. However, low levels of hemoglobin, SpO2, and TAPSE were independent predictors of low DLCO.
Метод комбінованого лікування медіастиніту після аортокоронарного шунтування
Authors: Demyanchuk V. B. , Kharenko Yu. O. , Stetsyuk I. O. , Tkachenko D. O.
Published: November 2024

Post-sternotomy mediastinitis (PM) or deep wound sternal infection is one of the most dreaded complications after cardiac surgery. Thanks to modern hygiene standards in hospitals and the rational use of antibiotics, the overall prevalence of PM is generally considered low. In cases of coronary artery bypass grafting using the internal mammary artery, this rate can significantly increase. However, even if this complication is relatively rare, it is associated with high mortality and morbidity level. Deep wound sternal infection not only leads to bad outcomes but is also accompanied by significant morbidity in surviving patients, prolonged hospital stays, increased treatment costs, and a substantial deterioration in long-term survival rates. At present, there is no standard treatment regimen for PM. Clinicians can choose different methods depending on the classification form of the disease, but all without exception include three main concepts: infection control, classical, irrigation, or vacuum wound drainage, and its reconstruction. Today, surgeons continuously propose new treatment methods, all of them have its own advantages and disadvantages as well. We present a case report of successful combined treatment (vacuum therapy followed by thoracoplasty) of PM after coronary artery bypass grafting.
Urinary stone disease in pediatric patients: a mixed-methods study
Authors: Önal Hülya Gözde , Semet Yonca
Published: November 2024

Aims: Childhood urinary stone disease (USSD) varies in frequency based on several factors such as, gender, age, body mass index, geography, diet, genetic disorders, and kidney anatomy. This study aims to retrospectively evaluate the demographic and clinical characteristics, symptoms, diagnostic methods, predisposing factors, associated urinary system anomalies, treatments, and prognosis of patients diagnosed with USSD in our clinic over the past three years.
Methods: This mixed-methods study retrospectively examined the records of 175 patients diagnosed with USSD between April 2020 and May 2023. Demographic data, symptoms, laboratory results, imaging findings, and treatment outcomes were analyzed. Additionally, qualitative data were gathered from semi-structured interviews with 10 volunteer participants to understand the impact of symptoms on their lives.
Results: Among the 175 pediatric patients diagnosed with urolithiasis, 120 (68.5%) were symptomatic, with common complaints such as irritability (29.1%), pain (18.2%), vomiting (23.4%), and macroscopic hematuria (20%). Significant differences were observed in symptoms based on age and stone size, with older children more likely to experience pain and hematuria, while younger children showed more irritability (p
Investigation of the chemical composition, antioxidant and anticholinesterase activities of Consolida orientalis
Authors: Sönmez Gürer Eda , Karadağ Ayşe Esra , Baydar Rengin , Demirel Melek
Published: November 2024

Aims: It is known that a decrease in the amount of acetylcholine in the body, which is known to be responsible for learning and cholinergic activity in the nervous system, causes Alzheimer’s disease. Acetylcholine is destroyed by acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE) enzymes in the nervous system. Consolida orientalis (C. orientalis) is a species that belongs to the Ranunculaceae family and grows naturally in many parts of the world. It is known that it plays a role in many biological activities thanks to its content of important phytochemical components such as phenolics and alkaloids. In this study; It was aimed to investigate the antioxidant activity, AChE and BChE enzyme inhibition activities of C. orientalis flower extracts.
Methods: The chemical content of ethanol extracts obtained from the flowers of C. orientalis plant, which was collected and identified from Sivas İmaret village between June and July 2023, was examined with 6 different reference substances (gallic acid, rosmarinic acid, myrcetin, quercetin, apigenin and camphorol). Antioxidant activity was determined by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) tests. Ascorbic acid and trolox were used as positive controls. The inhibition capacity of the samples on AChE and BChE enzymes was determined by the Ellman method.
Results: Chemical content analysis of the extract was performed by high pressure liquid chromatography (HPLC) and only gallic acid was detected among the standard compounds. When C. orientalis ethanol extracts were examined with DPPH and ABTS tests, they showed low-moderate antioxidant activity (IC50 (µg/ml) DPPH=4.8, IC50 (µg/ml) ABTS=4.4) compared to standard substances. C. orientalis ethanol extract was studied at a concentration of 20 µg/ml. The extract inhibited the AChE enzyme at 66.5% and the BChE enzyme at 53.2%. It was observed that the extract inhibited both enzymes at moderate to good levels, although not higher than galantamine used as positive control.
Conclusion: This study shows us that C. orientalis flowers have therapeutic potential for the effective management of neurological disorders due to their antioxidant and anticholinesterase activity. It is thought that our data will contribute to the literature as a preliminary study for the development of a new phytotherapeutic agent in the treatment of Alzheimer’s disease.
Is there a role of genetic tendency in post-COVID pulmonary thromboembolism?
Authors: Akkurt Esma Sevil , Bulut Sertan , Şahin Özdemirel Tuğçe , Mutlu Nihal , Ensarioğlu Kerem , Akıncı Özyürek Berna
Published: November 2024

Aims: COVID-19 is a multisystemic disease characterized by endothelial dysfunction. The improper activation of the coagulation cascade may lead to thromboembolic events, which are presumed to contribute to the disease’s overall high morbidity and mortality. This research examines the role of thrombophilia mutations in patients diagnosed with post-COVID pulmonary thromboembolism.
Methods: Between May 2020 and December 2020, 61 patients were diagnosed with pulmonary thromboembolism (PTE). Thirty-two patients were positive in COVID-19 -RT-PCR testing, and 29 patients were identified with non-COVID PTE. All PTE diagnoses were made by thorax computed tomographic angiography. Demographic characteristics, genetic mutation results, and laboratory values of the patients were retrospectively evaluated.
Results: The median age of patients was 56 years (25-81), and most patients (n=43,70.5%) were male. There was no difference between factor 5 Leiden mutation, while prothrombin 20210A mutation was more commonly observed in post-COVID patients (p
Clinical research for low back pain in Turkiye: analysis of PubMed-indexed randomized controlled trials
Authors: Topaloğlu Mahir , İş Enes Efe
Published: November 2024

Aims: Low back pain (LBP) is a prevalent condition and a major contributor to disability worldwide. Despite bibliometric analyses of LBP literature, no study has specifically explored Turkiye’s contribution to this field through randomized controlled trials (RCTs). This study aims to examine the characteristics of Turkiye-based RCTs on LBP, utilizing PubMed, the most frequently used biomedical search engine.
Methods: A comprehensive search was conducted on PubMed using the terms “low back pain [Title]” and “(Turkiye) OR (Turkiye).” Only interventional RCTs were included. Data points such as publication year, open-access status, first author’s specialty, study content, journal quartile (Web of Science), and citation count (Google Scholar) were analyzed.
Results: Most publications are authored by Physical Medicine and Rehabilitation (PMR) specialists (26) and physiotherapists (24), with emergency medicine specialists (6) in third place. The number of publications increased over time, peaking in 2021 (10). Most publications appeared in Q1-Q2-Q3 journals (67). The average citation count is 46.9, median is 29, ranging from 0 to 305, with citation counts strongly influenced by publication year (p
Coping strategies in bariatric surgery candidates: a case-control study
Authors: Şahin Can Merve , Yürür Emre Kaan , Türk Ezgi , Çay Ferhat
Published: November 2024

Aims: The aim of this study was to examine the relationship between coping strategies and some clinical and sociodemographic characteristics of people applied for metabolic bariatric surgery.
Methods: Forty people who applied to Balıkesir University Health Training and Research Hospital, Department of General Surgery to undergo bariatric surgery between August 2023 and November 2023 and 40 healthy volunteers with normal weight were included in the study. Sociodemographic data form and Coping Attitudes Assessment Scale (COPE) were applied to all participants.
Results: COPE positive reinterpretation and development, active coping, and planning subscale scores were statistically significantly higher in individuals with obesity, whereas focusing on the problem and venting of emotions, mental disengagement, and substance use subscale scores were lower in obese individuals compared to non-obese individuals (p
A rare form of tuberculosis: a case of tuberculosis verrucosa cutis
Authors: Dalmanoğlu Enes
Published: November 2024

Cutaneous involvement is a relatively uncommon manifestation of tuberculosis. Cutaneous lesions account for less than 2 percent of all extrapulmonary manifestations. Due to the paucibacillary nature of the lesions, there is a potential for misdiagnosis, which could result in the chronicity of the skin infection. This article presents the case of a 34-year-old male butcher who presented with plaques exhibiting characteristics of verrucosa, acanthosis, and hyperkeratosis on both fingers for a period of 10 years. The diagnosis of Mycobacterium tuberculosis was confirmed by histopathologic examination. The patient was subsequently treated with a standard anti-tuberculosis regimen, which resulted in notable improvement in the skin lesions.
Kepemimpinan dan Lingkungan Kerja Terhadap Kinerja Karyawan Memulai Kepuasan Kerja Pada PT. Bumi Sentosa Dwi Agung
Authors: Lesmana Fadli , Idris Idris , Asiati Diah Isnaini
Published: November 2024

Purpose - This study aims: (1) to determine the effect of leadership style and job environmenton job satisfaction at Bumi Sentosa  Dwi Agung, Ltd, (2) To determine the effect of leadership style and job environmentonemployee performance at Bumi Sentosa  Dwi Agung, Ltd,(3) to determine the effect of leadership style and job environmenton employee performance  through  job satisfaction at  Bumi Sentosa.Design/methodology - The research design used in this study is associative. The variables used were ndependent variables are Leadership Style (X1) and Job Environment (X2), the intervening  variables is Job Satisfaction (Y), and the dependent variables is Employee Performance (Z). Data collection technique used documentation and questionnaires. The population in this study as much as 150 employees, analytical techniques used are cluster sampling, so that the sample used as much as 110 employees. The analytical method using Path Analysis. Findings - Based on the findings that: (1) There is a positive and the significant effect of leadership style and job environment on the job satisfaction at Bumi Sentosa Dwi Agung, Ltd, (2) There is a positive and the significant effect of leadership style, job environment, and job satisfaction on the employee performance at Bumi Sentosa Dwi Agung, Ltd, and (3) There is a positive but not significant effect of leadership style and job environment on employee performance through the job satisfaction at Bumi Sentosa Dwi Agung, Ltd.
Anaisis Rasio Kecukupan Modal Kerja Pada PT Perkebunan Mitra Ogan Palembang
Authors: Bakti Rendra
Published: November 2024

Purpose - Working capital is very important for any company,  because almost all companies need working capital to finance day-to- day activities operasinal. Companies are required to constantly improve its efficiency so as to achieve the objectives expected by the company to achieve the optimal profit.Design/methodology  -  In  the absence  of sufficient working capital,the operational activities of a company may not run smoothly. This study aims to find out how the capital adequacy ratio. This research was conducted at PT Mitra Ogan plantation Palembang. The data used are secondary data from the financial statements Plantation Mitra Ogan Palembang.Findings - Where the results of analysis of the capital adequacy ratio  at the company's work will provide an overview of how the company can manage its working capital well. If the company can use working capital well, it will obtain sufficient capital. Conversely, when the company suffered a shortage or reduction in working capital, will encourage companies to experience credit with a bank or other outside parties and may hamper the business operational.
PENGARUH GAYA KEPEMIMPINAN DAN KEPUASAN KERJA TERHADAP KINERJA GURU SERTA DAMPAKNYA DALAM PENGAMBILAN KEPUTUSAN DI SMA DAN SMK MUHAMMADIYAH KOTA PALEMBANG
Authors: Fauzi Taty , Andriani Yulia , Hendro Omar
Published: November 2024

ABSTRACTPurpose - This study aims to determine and analyze, 1). The influence of leadership style on teacher performance. 2). Effect of satisfaction on teacher performance. 3). The influence of leadership style has an impact on decision making. 4). The effect of job satisfaction has an impact on decision making at the Muhammadiyah High School and Vocational School in Palembang, and 5). The effect of teacher performance has an impact on decision making.Design/methodology - The design of this research is associative research by connecting between variables. The data used in this study were primary and secondary data, and respondents' answers were 80 teachers in the Muhammadiyah High School and SMK Palembang City. The analytical method used is path analysis and through testing the validity and reliability. Test data used to determine the characteristics of the data are the normality test and linearity test. The test model used consisted of multicollinity test and heterodecacity test.Findings - 1). Teacher leadership style and job satisfaction significantly influence teacher performance. 2). Leadership style and job satisfaction have an impact on decision making. 5). Teacher performance has an impact on decision making in the Muhammadiyah High School and SMK Palembang City. Implications: This study provides results that motivation and competence are supporting factors for improving employee performance.Keywords : Leadership Style, Job Satisfaction, Performance and Decision Making.
PENGARUH MOTIVASI, DISIPLIN KERJA DAN KOMPENSASI TERHADAP KINERJA KARYAWAN PADA PT BENWIN INDONESIA DI KOTA BATAM
Authors: Sherlie Sherlie , Hikmah Hikmah
Published: November 2024

ABSTRACT Purpose - This study airms to determine the effect of motivation, work discipline and compensation on employee performance at PT Benwin Indonesia in Batam City.Design/methodology - The number of samples taken for this study were 103 respondents. The sample collection technique in this study was carried oit by sampling saturation. The data collection technique used in this study was a questionnaire distributed to all employees of PT Benwin Indonesia. The calculation process uses SPSS Software version 25.0. data analysis method in this research uses multiple linear regression analysis.Findings - The results showed that motivation, work discipline and parcial and simultaneous compensation significantly affected employee performance at PT Benwin Indonesia. The value of R square is 0.194 or 19.4%. this shows that motivation, work discipline and compensation influence 19,4% of employee performance while the remaining 80,6% is influenced by other variables outside of this study.Keywords :Compensation, Employee Perfomance, Motivation, Work Discipline.
PENGARUH MOTIVASI, KOMPENSASI DAN KOMPETENSI TERHADAP KINERJA PEGAWAI PENGELOLA KEARSIPAN YANG ADA DI LINGKUNGAN PEMERINTAH KABUPATEN OGAN KOMERING ILIR
Authors: Candra Alek , Fatimah Fatimah
Published: November 2024

Purpose - This study aims to determine the effect of motivation, compensation and competence on the performance of records management employees in the Ogan Komering Ilir Regency  Government.Design/methodology - The design of this research is associative research by connecting between variables. The data used in this study are primary and secondary data, and respondents' answers are 120 employees  in  the  Government  of  Ogan  Komering  Ilir  Regency. The analytical method used is multiple linear regression and through testing the validity and reliability. Test data used to determine the characteristics of the data are the normality test and linearity test. The test model used consisted of multicollinity test and heterodecacity test, assisted by SPSS for windows version 22 with a significance level of  0.05.Findings - The results of multiple linear regression testing show compensation motivation and competence together have a significant influence on employee performance. Partially motivation has a positive and significant effect on employee performance, competence has a positive and significant effect on employee performance, while compensation has no positive and significant effect on employee performance.Implications: This study provides the results that motivation and competence are supporting factors for improving employee performance..
Pengaruh Likuiditas, Leverage Dan Profitabilitas Terhadap Harga Saham Pada Perusahaan Sub Sektor Pertambangan Batu Bara Yang Terdaftar Di Bursa Efek Indonesia
Authors: Kosim Belliwati , Safira Maya
Published: November 2024

Purpose - This research aimed to find outthe effect of liquidity, leverage, and profitability on stock prices in coal mining sub-sector companies listed on the Indonesia Stock Exchange.Design/methodology - For sampling using non-probability sampling with a purposive sampling method, the sample was used 12 companies. The data was needed secondary data obtained from the Indonesia Stock Exchange through the website www.idx.co.id and for collection data used the method. The analysis technique used in this study was multiple linear regression analysis, classic assumption test, and hypothesis testing.Findings - For sampling using non-probability sampling with a purposive sampling method, the sample was used 12 companies. The data was needed secondary data obtained from the Indonesia Stock Exchange through the website www.idx.co.id and for collection data used the method. The analysis technique used in this study was multiple linear regression analysis, classic assumption test, and hypothesis testing. The results of the study of multiple linear regression Y = -1,651 + 0.594 (X­_1) + 0.0760 (X_2) + 0.517 (X_3), F test (simultaneous test) with F_count18.445> F_table 2.77 or significant F 0.000 < ? 0.05 means that there was a significant influence of liquidity, leverage, and profitability simultaneously on stock prices and t test (partial test) on liquidity t_count22.267> t_table 2.0024 and significant liquidity 0.027  ttable 2.0024 and significant leverage of 0.855> 0.05 this indicates that there was no partial leverage effect on stock prices and significant profitability of 0,000 <0.05 this indicates that there was a partial effect of profitability on stock prices while the leverage tcount = 0.183 <ttable 2.0024