bluuebunny/crossref_metadata_2025 huggingface dataset:
Haglund's Syndrome
Authors: Sanga Aradhana , Kushwaha Rajesh K , Vidrohi Rakesh K , Sanga Prerna , Dey Saikat Kumar
Published: February 2023

Background:

Haglund's syndrome an important cause of posterior heel pain presents with a prominent bony contour, a retrocalcaneal bursitis or achillis tendinitis these can also occur in isolation hence for the diagnosis of etiology of Haglund's disease certain radiological parameters and soft tissue parameters have been created to evaluate the anatomical variations which will assist in its exact diagnosis. Study aims to distinguish between the bony and soft tissue causes of Haglund's disease radiologically.

Methodology:

After Institutional ethical committee clearance an observational cross-sectional study was conducted with subjects coming to radiology OPD for X-ray foot with complains of posterior heel pain fulfilling inclusion and exclusion criteria were examined for X-ray lateral view of foot. Parameters like calcaneal inclination angle (CIA), Fowler Philip angle (FPA), parallel pitch line (PPL), Steffenson & Evenson angle (SEA) measured, posterior/calcaneal spur and posterior calcaneal step were noted. The data obtained was analyzed for mean, Standard deviation, sensitivity % and false negative %.

Result:

Sensitivity of the parameters were analyzed to find CIA, SEA &PPL to be 63.3%, 55% and 55% sensitive respectively. CIA could be assigned most sensitive but regarding soft tissue parameters none were sensitive.

Conclusion:

CIA, SEA & PPL were found to be sensitive among bony parameters. But none of the soft tissue parameters were sensitive radiologically highlighting a need for its correlation with clinical symptom in peripheral health centers where MRI is not available. Sensitivity of bony and soft tissue parameters were analyzed to find CIA, SEA & PPL to be sensitive. CIA could be assigned most sensitive among bony parameter but with regards to soft tissue parameters none were sensitive.
Histopathology of Pigment dispersion syndrome and glaucoma
Authors: Das Dipankar , Kuri Ganesh Chandra , Tayab Shahinur , Bhattacharjee Harsha , Deshmukh Saurabh , Deka Apurba
Published: February 2023

Pigment dispersion syndrome (PDS) can have varied manifestations. Anterior and posterior segment involvement by dispersed pigments was documented in gross pathology and by staining under microscopy. Pigmentary changes in the sclera, cornea, anterior chamber, iris, trabecular meshwork, lens, and retinal pigment epithelium and optic nerve findings were consistent with PDS. External scleral and vitreous pigmentation has never been reported before in the scientific literature. Retinal pigment degeneration and granule dispersion were seen throughout the retina which could be a contributing factor in the etiology of PDS.
Surgical treatment of a chronic foveal retinal detachment combined with staphyloma, foveoschisis, and macular hole
Authors: Karmiris Efthymios , Chalkiadaki Evangelia , Fydanaki Ourania , Apostolopoulos Michael
Published: February 2023

To present a case of anatomical success and visual improvement after the treatment of a long-standing foveal retinal detachment in a staphylomatous myopic eye with foveoschisis and macular hole. A 60-year-old woman with high myopia presented with foveoschisis and a lamellar macular hole in her right eye. After 2 years of follow-up without deterioration, her eye developed a full-thickness macular hole and a foveal retinal detachment which caused a severe reduction in visual acuity. However, the patient had no surgical treatment for her condition at that time. Vitrectomy was performed 2 years after the retinal detachment formation. Regardless of the longstanding detachment, anatomical success, and visual improvement were evident after the surgery. Despite a 2-year longstanding foveal detachment on a highly myopic eye with foveoschisis and macular hole, surgical repair could still be satisfactory.
Reticular corneal epithelial edema with topical netarsudil
Authors: Parmar Dipali P. , Bhole Pradnya K. , Garde Pawan V.
Published: February 2023

Rho-associated protein kinase inhibitor (ROCK) therapy for corneal endothelial dysfunction or damage other than glaucoma has been reported with few ocular side effects. We report reticular epithelial edema (REE) with netarsudil (0.02%) therapy in four cases with different clinical scenarios (three cases with corneal transplant and one case postcataract extraction). REE developed in all cases variably and cleared on cessation of netarsudil in three cases. One case was continued on netarsudil due to REE sparing the visual axis with no active ocular complaints. Partial clearance of stromal edema observed in all cases was correlated clinically to visual acuity considering existing comorbidities in an individual case.
Evaluation of twenty-seven-gauge vitrectomy for complex proliferative diabetic retinopathy
Authors: Verma Saurabh , Shiny Hannah , Azad Shorya Vardhan , Kumar Vinod
Published: February 2023

PURPOSE:

To evaluate the outcomes of twenty-seven-gauge (27G) vitrectomy in cases with complex proliferative diabetic retinopathy (PDR).

METHODS:

This was a retrospective interventional study of eyes that underwent 27G vitrectomy for complex PDR. The demographic profile, history, examination findings, and intraoperative surgical steps (especially use of other instruments such as intravitreal scissors/forceps) were reviewed. All the eyes were followed up for a minimum of 3 months at 1-week, 1-month, and 3-month interval. Visual acuity, intraocular pressure (IOP), and retinal status were documented at every follow-up.

RESULTS:

Nineteen eyes of 17 patients with complex PDR were included in the study. Seven eyes had tractional retinal detachment involving the macula, three had tractional retinal detachment threatening the macula, one had secondary rhegmatogenous retinal detachment, and eight eyes had nonresolving vitreous hemorrhage along with thick fibrovascular proliferation (FVP) at posterior pole. Anatomical attachment was seen in all cases at the end of follow-up with a single surgery. Visual acuity improved from logMAR 2.5 preoperatively to logMAR 1.01 at 3 months (P = 0.0003). None of the cases required use of intravitreal scissors/forceps for the removal of FVP. Early postoperative vitreous hemorrhage was seen in two eyes. Hypotony was not seen in any eye, while increased IOP was seen in five eyes.

CONCLUSION:

27G vitrectomy is a safe and effective technique in cases with complex diabetic surgery. Due to smaller size cutter, it offers advantages in the dissection of tissue and is associated with lower incidence of early postoperative hemorrhage.
Toxic anterior segment syndrome and Urrets-Zavalia syndrome
Authors: Ganesan Niruban , Srinivasan Renuka , Kaliaperumal Subashini
Published: February 2023

PURPOSE:

The purpose of the study was to analyze the outcomes of patients with toxic anterior segment syndrome (TASS) and Urrets-Zavalia (UZ) syndrome.

MATERIALS AND METHODS:

The records of all patients with TASS and UZ syndrome were studied. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and the details of surgeries performed were recorded at 1 and 3 months. We studied the changes in CDVA and IOP using repeated-measure ANOVA and paired t -test, respectively.

RESULTS:

Four patients (44.4%) developed refractory UZ syndrome, and five (55.6%) patients had TASS. At the end of 3 months of follow-up, all nine patients had concentric rings of iris atrophy and corneal edema. None of the cases had hypopyon or vitritis. Peripheral anterior synechiae (PAS) with secondary glaucoma was present only in cases of UZ syndrome. Among the four cases of UZ syndrome, goniosynechialysis was performed for 2 cases and trabeculectomy for one case. Despite these interventions, IOP could not be controlled. Patients in the TASS group did not exhibit PAS formation, and IOP was normal, but corneal edema and concentric rings of iris atrophy persisted. Descemet's stripping endothelial keratoplasty was performed for all the TASS cases. There was a statistically significant drop in CDVA (P = 0.028) and an increase in IOP (P = 0.029) at 3-month postcataract surgery.

CONCLUSION:

TASS and UZ syndrome could result in sight-threatening complications. They may be considered diseases of the same entity as both the conditions were found in the same cluster. TASS could be considered as an abortive attack of UZ syndrome.
Optic neuritis presented as the only manifestation of neurosyphilis
Authors: Roy Tanima , Gupta Anusen Das , Islam Aneeka Rahnuma
Published: February 2023

Here, we report a case of syphilis presented with optic neuritis to consider neurosyphilis as one of the differential diagnoses of optic neuritis. A 25-year-old male attended at outpatient department of chittagong eye infirmary and training complex institute with a history of a sudden loss of vision in the left eye for 20 days. On eye examination, the patient had reduced visual acuity on the left eye (6/60), and the left pupil showed a relative afferent pupillary defect and swollen left optic disc. No other abnormalities were found in a routine blood test and magnetic resonance imaging of the brain. Intravenous corticosteroid was administered for 3 days followed by oral corticosteroid. His vision was gradually improving within a month and became 6/9 in the left eye, but after a month, the patient returned with the blurring of vision in the same eye for 3 days. An extensive serum biochemical and serological test and cerebrospinal fluid (CSF) analysis was done including syphilis serology and human immunodeficiency virus (HIV) serology. Venereal disease research laboratory (VDRL) test and Treponema pallidum hemagglutination assay (TPHA) were found positive with high titer (1:1280) and rapid plasma reagin (RPR) titer of 1:64 in blood. The CSF analysis showed leukocytosis, and VDRL and TPHA were also found positive with high RPR titer. The HIV serology test was negative. The patient was treated with injectable ceftriaxone 2 g intravenously for 14 days and also injectable corticosteroid. His vision was improved within this period. Unilateral optic neuritis due to syphilis without other ocular features is uncommon but should be considered if a patient presents with visual loss and optic disc swelling. Early diagnosis based on clinical suspicion and prompt management is important to prevent visual impairment and subsequent neurological complications.
Pupillary block glaucoma due to anterior migration of nonemulsified silicone oil in a phakic patient
Authors: Al-Habsi Shihab Hilal , Al-Abri Mohamed S.
Published: February 2023

This report describes a case of acute pupillary block glaucoma related to migration of nonemulsified silicone oil into the anterior chamber (AC) in a young phakic patient. A 24-year-old male diabetic patient underwent uneventful left eye pars plana vitrectomy (PPV) with silicon oil endotamponade for diabetic macula-off tractional retinal detachment. Two weeks after discharge, he presented with severe left eye pain. Examination revealed hand motion vision, high intraocular pressure (IOP) of 67 mmHg with ciliary injection, corneal edema, and two large nonemulsified silicone oil bubbles in the AC at the pupillary margin. Medical management with topical antiglaucoma medications (AGMs) and intravenous acetazolamide and mannitol failed to reduce the IOP. The patient underwent left eye PPV, silicone oil removal, and AC wash. IOP was eventually controlled after the operation without AGM. Pupillary block glaucoma after silicone oil injection is well recognized in aphakic patients, but ophthalmologists should be aware that it can occur in phakic and pseudophakic patients, particularly in complicated cases and patients with a weakness of the iris–lens diaphragm.
The effects of rehabilitation on functional independence of Eastern Taiwanese children with rare or genetic diseases
Authors: Lin Yu-Chuan , Weng Chun-Ying , Liang Chung-Chao , Chu Shao-Yin
Published: February 2023

ABSTRACT

Objectives:

This study investigated the effects of outpatient rehabilitation therapy (RT) on the functional performance of children from Eastern Taiwan with rare or genetic diseases.

Materials and Methods:

This retrospective observational cohort study included 73 children from Eastern Taiwan who were affected with rare or genetic diseases, with an average age of 8.57 ± 5.33 years (47 boys and 26 girls). Each child received the goal-directed therapy known as outpatient RT, which was delivered by a multidisciplinary team of specialists. To assess the effectiveness of RT, the WeeFIM-C questionnaire data were collected and analyzed.

Results:

After receiving outpatient RT, most of the children only required low-to-moderate assistance with self-care tasks (4.36 ± 2.38), and they could perform mobility-related activities under supervision or independently (5.70 ± 2.29). Moreover, most only required minimal assistance with tasks related to cognitive functioning and tended to complete such tasks under supervision (4.97 ± 2.05). The functional performance was significantly different among three studied groups, in terms of self-care (F
[2, 68] = 5.42, P < 0.007), mobility (F
[2, 68] = 8.17, P < 0.001), cognitive functioning (F
[2, 68] = 3.31, P < 0.042), and overall (F
[2, 68] = 6.44, P < 0.003) functional performance.

Conclusion:

The results of this study demonstrated that the functional status was different among three studied groups in terms of self-care, mobility, and cognitive functioning after receiving outpatient RT.
Development and Implementation of a Pharmacist-Led Proton Pump Inhibitor Deprescribing Algorithm in a Geriatric Ambulatory Office
Authors: Leszcynski Leah , Bente Jessica
Published: February 2023

Background The American Geriatrics Society 2019 Updated Beers Criteria© recommends avoiding scheduled use of proton pump inhibitors (PPIs) for greater than eight weeks in older people because of potential risk of bone loss and fractures and Clostridioides
difficile infection. There are limited studies evaluating the effectiveness of deprescribing PPIs in this patient population. Objective The purpose of this study was to evaluate the implementation of a PPI deprescribing algorithm in a geriatric ambulatory office on the
appropriateness of PPI use in older people. Methods This single-center study evaluated PPI use in a geriatric ambulatory office pre- and post-implementation of a deprescribing algorithm. Participants included all patients 65 years of age or older and a documented PPI on
their home medication list. The PPI deprescribing algorithm was developed by the pharmacist using components of the published guideline. The primary outcome was the percentage of patients on a PPI with a potentially inappropriate indication before and after implementation of this deprescribing
algorithm. Results At baseline, 228 patients were treated with a PPI, and 64.5% (n = 147) of patients were treated for a potentially inappropriate indication. Of the 228 patients, 147 patients were included in the primary analysis. Potentially inappropriate use of PPI significantly
decreased after implementation of a deprescribing algorithm from 83.7% to 44.2% in the cohort of patients who were eligible for deprescribing (difference 39.5%; P < 0.0001). Conclusion Potentially inappropriate PPI use in older adults decreased after implementation
of a pharmacist-led deprescribing initiative, supporting the role of pharmacists on interdisciplinary deprescribing teams.
aproximación, de los Almacen de Datos, en el Seguimiento de Egresados en Eudación Superior.
Authors: Madrid José David , Ponce Mendoza Ulises , García Gorrostieta Jesús Miguel
Published: February 2023

El alamcen de datos se diseño en la Universidad de la Sierra, organismo descentralizado del Estado de Sonora, Mexico, se encuentra ubicada en  la región serrana en el municipio de Moctezuma. Los estudios de seguimiento de egresados y empleadores son una estrategia que permite la autoevaluación,  además de conocer la  trayectoria laboral  y profesional de los egresados de los diferentes  programas educativos que ofrece la institución. Uno de los resultados que más se desea conocer en estos estudios, es la opinión de los egresados con respecto a la formación profesional que obtuvieron, como ha influido ésta en su inserción en el mercado laboral, además, si los programas de estudios son adecuados a las necesidades de las demandas de la región. Por lo anterior, en este trabajo se describe el proceso de implementación de un Almacén de Datos en especifico el modelo Multimdimensional de sastisfacción para el Seguimiento de Egresados,  ya que este representa el proceso de reunir información histórica de una organización en un depósito central y se ha convertido en una tecnología fundamental.
PERAN KEPEMIMPINAN CAMAT DALAM PEMBINAAN PEGAWAI
Authors: Novita Frinda , Bedasari Hafzana , Carda Lilif
Published: February 2023

Belum tercapainya kinerja aparat sesuai dengan apa yang di inginkan disebabkan kurang disiplinnya aparat dalam melaksanakan tugas dan tanggung jawab sesuai dengan tupoksi yang dimiliki dan sesuai aturan-aturan yang ada dan berlaku. Dari hasil pengamatan penulis terhadap tingkat kehadiran aparat, dimana adanya ketidak patuhan sebagian aparat terhadap aturan tata tertib seperti datang dan keluar kantor tidak sesuai waktunya dan meninggalkan kantor tanpa meminta izin kepada pimpinan sehingga berdampak pada adanya waktu lembur untuk menyelesaikan tugas-tugas ataupun pekerjaan yang tertunda. Belum maksimalnya tingkat kinerja dan masih rendahnya tingkat disiplin pegawai tersebut karena iklim pekerjaan tersebut belum mempunyai pekerjaan sesuai dengan bidang tugas atau sesuai kemampuannya. Camat sebagai penguasa pemerintah kecamatan berupaya untuk lebih meningkatkan perannya agar kecamatan Buru yang relatif masih berumur muda tidak kalah bersaing dengan kecamatan-kecamatan lain yang sudah lama. Oleh karena itu masyarakat mengharapkan dalam kepemimpinan Camat Buru yang baru dapat lebih meningkatkan perannya didalam meningkatkan efektifitas kerja aparat kecamatan. Dari penelitian ini dapat diketahui bahwa 5 indikator yang diteliti yaitu Bimbingan, Supervisi, Konsultasi, Pemberian Pedoman, dan fasilitasi dengan 2 orang responden diperoleh tanggapan responden yang menyatakan baik dengan skor 1176, kemudian responden yang menyatakan cukup baik skornya 400, dan yang menyatakan kurang baik skornya 125. Dengan demikian secara keseluruhan dapat diketahui bahwa Pembinaan Pegawai di Kecamatan Buru Kabupaten Karimun mendapatkan jumlah skor rata-rata 340,2 dan dinyatakan dalam kategori “Baik”.
PENINGKATAN KUALITAS PELAYANAN KEPOLISIAN DALAM UPAYA MENANGANI PENGADUAN MASYARAKAT PADA POLSEK LIMA PULUH KOTA PEKANBARU
Authors: Anggraini Rini , Hernimawati Hernimawati , Marlinda Pebriana
Published: February 2023

Polsek Limapuluh merupakan salah satu Polsek Urban ( perkotaan ) yang berada di tengah kota Pekanbaru dan tak luput dari tindak kejahatan di lingkungan masyarakat dan menaungi 2 ( Dua kecamatan ) yaitu Kecamatan Limapuluh dan Sail.Untuk menangani hal tersebut Polsek Limapuluh berusaha dengan meningkatkan kualitas pelayanannya dalam menganangani pengaduan masyarakat yang ditujukan untuk mewujudkan keamanan masyarakat yang maksimal dan baik. Teori yang digunakan yaitu teori Gesperz dalam Hardiansyah ( 2011 : 51 ) Yaitu : ketepatan waktu pelayanan, Akurasi pelayanan, kesopanan dan keramahan dalam memberikan pelayanan, Tanggung Jawab, kelengkapan, kemudahan, Variasi model Pelayanan, Pelayanan Pribadi kenyamanan dan Atribut. Peningkatan Kualitas Pelayanan Kepolisian Dalam Upaya Menangani Pengaduan Masyarakat Pada Kantor Polsek Limapuluh Pekanbaru dari indikator yang ada bahwa sudah berjalan baik namun, masih ada beberapa indikator yang belum sepenuhnya berjalan maksimal seperti masih adanya sumber daya yang belum cukup berkompeten dalam menguasai bidangnya (sentral pelayanan) serta menguasai alat komputer sehingga masih ditemukan kesalahan atau kurang cermat dalam pembuatan laporan.masih terdapat sarana prasarana yang belum sepenuhnya terpenuhi pada polsek Limapuluh.yang diharapkan kedepannya lebih baik lagi.
SIKAP NELAYAN TERHADAP BANTUAN ALAT TANGKAP DI DESA KELARIK UTARA KABUPATEN NATUNA
Authors: Habibah Habibah , Rahmawati Nanik , Syafitri Rahma
Published: February 2023

Kegiatan perikanan tangkap memiliki arti penting bagi sebagian besar masyarakat pesisir di Kabupaten Natuna. Kegiatan penangkapan ikan sangat berpengaruh terhadap kondisi sosial, ekonomi dan budaya. Guna menunjang kegiatan nelayan di Desa Kelarik, Pemerintah memberikan bantuan alat tangkap yang diharapkan mampu membantu meningkatkan kesejahteraan nelayan. Dalam perjalanannya, bantuan tersebut ada yang dimanfaatkan namuan ada juga bantuan yang diberikan tidak dimanfaatkan oleh nelayan. Penelitian ini dilakukan guna menjawab permasalahan tentang sikap nelayan terhadap bantuan alat tangkap dari pemerintah. Tujuan penelitian adalah untuk mengetahui dan mendeskripsikan sikap nelayan Desa Kelarik Utara Kecamatan Bunguran Utara Kabupaten Natuna terhadap bantuan alat tangkap. Dengan menggunakan metode penelitian kualitatif dengan pendekatan deskriptif, peneliti mendapati bahwa nelayan di Desa Kelarik rata-rata berpendidikan rendah. Sikap nelayan terhadap bantuan alat tangkap dari pemerintah terbagi ke dalam tiga kelompok, yaitu bersikap positif, bersikap negatif, dan bersikap netral (pasrah). Sikap-sikap tersebut dipengaruhi oleh, pengalaman, orang lain, pendidikan, agama, kebudayaan dan emosional.
PROSES INOVASI PELAYANAN MELALUI PROGRAM SATU BERKAS MINIMAL EMPAT PRODUK (SABER MEMPRO) DI KABUPATEN PELALAWAN
Authors: Ropizal Ropizal
Published: February 2023

The Saber Mempro program was formed due to the low coverage of Birth Certificates in Pelalawan Regency, which means that many Pelalawan people do not yet have a child's birth certificate, besides that, public awareness when dealing is still lacking due to the vulnerability of the village distance to Disdukcapil which uses fees, and government attention is still lack of socialization in providing effective services to the community. The purpose of this research is to find out. The purpose of this study was to determine the support and process of service innovation through the one file program of at least four products (Saber Mempro) in Pelalawan Regency. The research method used is qualitative research with a descriptive case study approach. The results of the study stated that the Mempro Saber Program at the Population and Civil Registration Office of Pelalawan Regency was carried out through an analysis of four stages in the innovation process: The stage of submitting an idea, having an idea first, the stage of evaluating ideas that will be followed up, the stage of developing ideas into reality, and the implementation stage according to Sherwood in Marzuki (2016:5).
Comparison of Atom Maps
Authors:   Interdisciplinary Center for Bioinformatics & Leipzig University, Leipzig, Germany, Gonzalez Laffitte Marcos E. , Beier Nora , Domschke Nico , Stadler Peter F.
Published: February 2023

The computation of reliable, chemically correct atom maps from educt/product pairs has turned out to be a difficult problem in cheminformatics because the chemically correct solution is not necessarily an optimal solution for combinatorial formulations such as maximum common subgraph problems. As a consequence, competing models have been devised and compared in extensive benchmarking studies. Due to isomorphisms among products and educts it is not immediately obvious, however, when two atom maps for a given educt/product pairs are the same. We formalize here the equivalence of atom maps and show that equivalence of atom maps is in turn equivalent to the isomorphism of labeled auxiliary graphs. In particular, we demonstrate that Fujita's Imaginary Transition State can be used for this purpose. Numerical experiments show that practical feasibility. Generalizations to the equivalence of subgraph matches, double pushout graph transformation rules, and mechanisms of multi-step reactions are discussed briefly.
Trees with Extremal Values of the Sombor-Index-Like Graph Invariants
Authors:   College of Mathematics and Statistics, Hunan Normal University, Changsha, China, Tang Zikai , Li Qiyue , Deng Hanyuan
Published: February 2023

Anew geometric background of graph invariants was introduced by Gutman, using the triangle formed by the degree-point, dualdegree-point, and the origin of the coordinate system, a number of new Sombor-index-like VDB invariants, denoted by SO1,SO2,..., SO6, were constructed by means of geometric arguments. In this paper, the chemical applicability of these Sombor-index-like graph invariants is investigated, and it is shown that almost all of these six indices are useful in predicting physicochemical properties with high accuracy compared to some well-established and often used indices. Also, we obtain a bound for some of the Sombor-index-like graph invariants among all (molecular) trees with fixed numbers of vertices, and characterize those (molecular) trees achieving the extremal value.
Segmental Optic Atrophy with Adrenoleukodystrophy ABCD1 Gene Variant
Authors:   Department of Neuroophthalmology, Aravind Eye hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India, Erdenechuluun Khishigdelger , R Sharanya ,   Department of Neuroophthalmology, Aravind Eye hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India, Kumar Karthik ,   Department of Neuroophthalmology, Aravind Eye hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India, Shah Virna ,   Department of Neuroophthalmology, Aravind Eye hospital and Postgraduate Institute of Ophthalmology, Coimbatore, India
Published: February 2023

We report a case of Adrenoleukodystrophy ABCD1 gene variant presenting with segmental optic atrophy in a 34-year-old male. The patient presented to our Neuro-Ophthalmology clinic with complaints of defective vision in both eyes, mild headache and gait disturbances. Ocular examination showed best corrected visual acuity of 6/24 in both eyes and fundus examination revealed temporal pallor of optic disc. Systemic examination revealed spastic paraparesis. Neuroimaging was advised which revealed well defined confluent symmetric bilateral T2/FLAIR hyperintense areas in parietal-occipital deep white matter and in the splenium of the corpus callosum, acoustic and optic radiations bilaterally. Genetic testing was positive for ABCD1 c.1966T>C (p.Ser656Pro) gene variant. X-linked adrenoleukodystrophy (X-ALD) is a rare neurodegenerative disease characterized by genetic mutation of the ABCD1 gene, primarily affecting males. Our patient presented with defective vision and walking problem due to Adrenoleukodystrophy ABCD1 gene variant. Ocular symptoms often occur after the systemic abnormalities are noted.
Work Life Balance of Women Faculty Working In HEIs with Special Reference to Bangalore City
Authors:   Assistant Professor, Department of Commerce, Kristu Jayanti College, Autonomous, Bangalore., J. Dr. Chandrakhanthan ,   Assistant Professor, Department of Commerce, Kristu Jayanti College, Autonomous, Bangalore., C. Mr. Dhanapal ,   Assistant Professor, Department of Commerce, Kristu Jayanti College, Autonomous, Bangalore.
Published: February 2023

Women are demonstrating greater passion and interest in the educational area as technology advances, and they are finding it increasingly difficult to balance their personal and professional lives. The importance of a faculty member in educational institutions' productivity cannot be overstated. To provide a high-quality service, they must be mentally and physically fit. The role of a faculty is very significant for the productivity of educational institutions. The majority of academics are women. As a result, it's crucial to observe how these women manage their job and personal lives. In this context, the paper analyses the work life balance challenges faced by women faculty working in HEIs and impact of work life balance on women faculties’ performance in HEIs by using primary data. Through a literature analysis, the study chose three important factors that were appropriate for the study scenario. Workload, social support, and childcare were chosen as independent variables, whereas work life balance was chosen as the dependent variable. The primary data was collected via a standardized questionnaire by the researchers. In this article, a survey of 35 Bangalore educational institutions is undertaken using a sample of 220 instructors to determine the true state of work-life balance. The study finds that the work-life balance situation for female faculty members is moderate, which can be improved by providing flexible working hours, transportation, residential facilities, child care centers, flexible work arrangements/job sharing, reduced working hours and workload, and child schooling. The result of the research will be helpful for the HEIs administrators, to identify the importance of work life balance of female faculty in order to improve the outcome of their institutions.
Rancang Bangun Sistem Informasi Geografis Menemukan Lokasi Dokter Hewan Berbasis Android
Authors: Sahrun Nori , Sularno Sularno
Published: February 2023

Geographic information systems (GIS) have the ability to connect various data at certain points on earth, combine, analyze, and finally map the results. Data will be processed in GIS spatial data which is geographically and location oriented data that has a certain coordinate system, as a basic reference. So the GIS application can answer several questions such as; location, conditions, trends, patterns and modeling. This capability distinguishes GIS from other information systems. By building a geographical information system it is hoped that it can help the public to find out where the location of veterinarians in the city of Padang is based on Android. So that people can more easily find the location of veterinarians in the city of Padang quickly and accurately that can be accessed via cell phones (Smartphones). In this geographic information system making additional application programs used are MapInfo, Android Studio, and other supporting applications.
Perancangan Sistem Informasi Posyandu Ibu Dan Anak Berbasis Web
Authors: Fachri Barany , Hendry Hendry , Zen Muhammad
Published: February 2023

Tomuan Holbung Village is a village in North Sumatra. As a village, there is still information that has not been accessed by many other people through public communication, namely the internet. Where there is a Posyandu currently has a meaningful role to support public health services. The role of the Posyandu is accompanied by the increasingly visible role of the community after the emergence of the Posyandu as a form of community-based health effort. Apart from that, Posyandu activities have been running smoothly so far because of the Posyandu Information System (SIP) book as an implementation guide. Technology contributes to structuring management systems and work processes in government and private agencies. One of the applications of Information Technology in village life is the use of a web-based Mother and Child Posyandu Information System. In this design, the web-based Posyandu information system is analysis, design, coding and testing as well as entity relationship diagrams in designing the database. The Posyandu information system is equipped with a web-based display so that users can adjust the contents in the system as a means of information in designing a web-based Mother and Child Posyandu Information System in Tomuan Holbung Village.
Some links between economic and social changes in rural areas and the need for reform in rural education
Authors: Bryden John
Published: February 2023

This paper discusses the principal economic and social changes taking place in rural areas of the OECD countries, identifies some of the key future challenges they face, and proposes some necessary shifts in the system of education of children and young people if these challenges are to be addressed.
Consequential Learning
Authors: Shelton Jack
Published: February 2023

Consequential Learning (CL) is an approach to rural education and development that links schools to communities through curricular and extracurricular projects and courses, in which students, using the tools and concepts of academic, technical, artistic, and business disciplines, are challenged to produce consequential public outcomes. Students, school staff, and external resource persons form a team to determine and complete projects that make a difference in the well-being of communities. The projects defme new roles and develop new skills for students and teachers; they involve, for clearly articulated tasks, "outsiders" who bring new expertise, opportunities, connections, and resources into schools. CL projects and approaches help delineate new purposes for schools (including community development and gathering local information) and c1arifybasic issues of education and community enhancement They demonstrate the potential for school and community partuerships to improve educational quality and community life.
Two Cubed
Authors: Loughland Tony , Healey Daryl
Published: February 2023

Teacher Education needs to move beyond the limitations of existing pre-service and in-service courses. Instead, teacher education should be regarded as a career long process of professional learning 'which takes place prior to and during pre-service, and continues through induction and inservice' (Gore, 1995). An innportaut step in this direction is partnerships between schools and teacher education institutions in initial teacher preparation. Many such partnerships already occur across states and institutions. This paper outlines a rationale for a teacher education course that seeks to achieve a partnership between Charles Sturt  University Dubbo and the Department of Education and Training (DET) in NSW within the framework of career long professional learning for teachers.

The existing political climate with the restructuring of the DET bureaucracy as well as the proposed NSW Institute of Teachers presents a serendipitous moment for the establishment of such a course. The course would follow what the author has termed the 'two cubed' model of teacher education. That is, the fIrst two years of teacher education in the university, followed by two years in school based teacher education (SBTE) with the fmal two years as a begirming teacher mentored by both the training and employing institutions. The initial teacher education course will be the Trojan horse that makes professional learning a formal part of the teaching profession as the interaction between the DET and Charles Sturt University creates professional learning opportunities for existing teachers. This professional learning will be linked strongly to the bioregion of the Murray-Darling Basin, thus addressing both the ecological and social sustainability issues of this region. As well, the qualifIcation gained will be for K-10, addressing the needs of middle school students in central and high schools in the central west of New South Wales.
Multilingualism and Local-Global Identities
Authors: Hartley Barbara
Published: February 2023

The purpose of this article is to examine the value accruing to a regional area in Australia from the location of an undergraduate Japanese language education program in a university in that area. The focus is on the manner is which the inclusion of such aprogram enhances the sustainability of the area. Sustainability is here defmed as the resilience demonstrated by social subjects in the absence:,ofthe full range of services available in more densely populated and resource advantaged areas. Such resilienceimplies an ongoing capacity on the part of subjects to contribute productively to social and economic networks in the area. The rliscussion includes two cases of graduates of the program under review. On the basis of these cases, the argument is advanced that local regional and rural area access to a tertiary sector second language program offers a unique and valuable strategic dimension to the personal and professional development of social agents in regional areas and to the sustainability of these areas generally.
A Principal's Perspective on Multiliteracies in an Australian Show Community
Authors: Fullarton Catherine , Danaher Geoff , Moriarty Beverley , Danaher Patrick Alan
Published: February 2023

The mobile community that owns and operates 'sideshow alley' in Australia's agricultural show circuits has traditionally been marginalised in terms of formal educational provision. However, the establislunent of the Queensland School for Travelling Show Children in 2000 reflected the aspirations of show people and sympathetic educators that education for mobile groups can be enacted differently. This different educational enactment is explored through the conceptual lens of a 'multiliteracies' framework (Cope & Kalantzis, 2000), which is used to identify and value the complex and diverse forms of sense-making that the show people deploy. This paper focuses on the perspective of the Principal of the school, who was one of the interviewees in the research reported here and also the lead author of this paper. Analysis of these data indicates that formal learning that embraces and enhances multiliteracies is one significant strategy for promoting education productively - and potentially transfonnatively - in such communities.
Ichimlik suvi tayyorlash tizimidagi ichki suv sarfini matematik modellashtirish
Authors: Rustamova Muxlisa
Published: February 2023

Maqolada ichimlik suvi tayyorlash tizimida aholiga va sanoat korxonalariga sarf bo‘ladigan suv miqdorini aniqlashda, ichimlik suvi tayyorlash stansiyasining ichki suv sarfini matematik modellashtirish masalasi o‘rganilgan.
Выражение педагогических взглядов на социальное становление личности ребенка в узбекских народных сказках
Authors: Абдуллаева Шахноза
Published: February 2023

В этой статье говорится о выражении педагогических взглядов на социальное становление личности ребенка в узбекских народных сказках.  Проанализированы исследования мировых ученых по индивидуальному развитию личности ребенка и выделены факторы, влияющие на социальное становление. Изучены примеры особенностей социального развития человека в узбекских народных сказках, а также объяснены основные идеи в них.
Maktabgacha yoshdagi bolalarda ekologik ta’lim berishda kuzatishning ahamiyati
Authors: Bekchanova Feruza
Published: February 2023

Bugungi kunda insoniyatning tabiatdan noto‘g‘ri foydalanishi oqibati tabiatda turli xil salbiy jarayonlarni kuzatyapmiz. Bunday holatlarning oldini olish uchun eng avvalo yosh avlodning ekologik madaniyatini oshirishimiz kerak. Uzluksiz ta’limning boshlang‘ich bo‘limi bu maktabgacha ta’lim muassasasi sanaladi. Shuning uchun maktabgacha ta’lim muassasasitarbiyalanuvchilarda biz ekologik madaniyatni shakllantirib borishimiz lozim. Bunda eng samarali usullardan biri - bu kuzatish hisoblanadi. Mazkur maqolada maktabgacha ta’lim muassasasi tarbiyalanuvchilarining ekologik tarbiyasida atrof-muhitning roli hamda bolalarning ekologik madaniyatini rivojlantirishning usullari yoritib berilgan.
Цифровое издательство: как технологии меняют способы чтения и прослушивания книг
Authors: Ражапов Дилшод
Published: February 2023

В настоящее время все больше людей предпочитают использовать цифровые платформы для чтения книг и прослушивания аудиокниг вместо традиционных печатных изданий. Согласно данным маркетинговых исследований, количество пользователей, использующих цифровые книги, постоянно растет, и в 2021 году ожидается около 1,08 миллиарда пользователей цифровых книг в мире. Это может быть связано с удобством использования цифровых платформ, которые позволяют скачивать и читать книги в любом месте и в любое время. Кроме того, цифровые книги часто стоят дешевле, чем их печатные аналоги. Дополнительными преимуществами цифровых книг являются возможность изменения размера шрифта, настройки освещения и цвета фона, а также поиск по тексту. Эти функции могут сделать чтение более удобным для людей с ограниченными возможностями зрения или находящихся в условиях плохого освещения. Аудиокниги также становятся все более популярными, и в 2020 году около 55 миллионов человек в США слушали аудиокниги. Кроме того, многие пользователи смартфонов и планшетов используют голосовых помощников для прослушивания аудиокниг. В целом, данные тенденции рынка цифрового издательства указывают на то, что использование цифровых книг и аудиокниг будет продолжать расти в будущем. Это создает новые возможности для авторов и издательств, чтобы приспособиться к изменяющимся потребностям и предпочтениям читателей.
Жиноят-процессуал ҳуқуқида оқлов ҳукмининг моҳияти
Authors: Пирназаров Абдурашид
Published: February 2023

Мақолада оқловнинг процессуал асослари, унинг тузилиши ва мазмуни таҳлил қилинади. Муаллиф оқлов ҳукмларини чиқариш муаммолари ва оқланганларни реабилитация қилиш институтини таҳлил этади. Оқлов ҳукмини чиқариш учун асослар ва уларнинг тартиби илмий таҳлил остига олинган. Оқлов ҳукмларини чиқариши орқали фуқаролар хуқуқларини кафолатлаш, бегуноҳ шахслар устидан ноқонуний, асосланмаган, адолатсиз ҳукмлар чиқармаслик ҳамда суд томонидан чиқарилаётган ҳукмларни сифат жиҳатдан яхшилаш, бу борада юзага келаётган муаммоларини тадқиқ этиш тадқиқотнинг асосий мақсади ҳисобланади.
Халқаро стандартлар ҳамда сифат менежменти тизимини ривожлантириш босқичлари
Authors: Аблакулова Муниса , Худайберганова Ноила
Published: February 2023

Маълумки сифат – инсонларнинг эҳтиёжлари ва талабларини қондириш билан асосланувчи маҳсулот, материал, иш тури, меҳнат, хизматлар ва шу кабиларнинг хусусиятлари ҳамда хусусий белгиларининг мажмуи бўлиб, улар қўйилган талаблар ва ўз вазифаларига тўлиқ мос келиши билан баҳоланади. ISO 9000 стандартида “Сифат – ўзига хос хусусиятдаги талабларга мослик даражаси” кўринишида талқин қилинади. Таълим сифати – жамиятда таълим жараёнининг ҳолати ва натижасини ҳамда шахснинг касбий компетентлигини шаклланиши ва  ривожланишини жамият талаби ва эҳтиёжига мос келишини аниқлайди. Таълим сифати икки жиҳатга эга: давлат таълим стандартларига мослик; истеъмолчи талабларига мослик.
Общие требования допустимости доказательств, полученных при проведении оперативно-розыскных мероприятий на стадии доследственной проверки
Authors: Ниязов Максуд
Published: February 2023

В статье анализируются различные аспекты оформления результатов и материалов оперативно-розыскной деятельности (далее-ОРД), в частности даются определения ОРД и оперативно-розыскным мероприятиям (далее-ОРМ) и сопоставляется значение указанных понятий, дается определение доследственной проверки, результатам и материалам оперативно-розыскной деятельности, указывается значимость оснований и условий, необходимых для проведения ОРМ, виды и классификация ОРМ. Также в данной статье проведено сравнительное исследование различных норм национального уголовно-процессуального законодательства, связанных с использованием доказательств, полученных посредством проведения ОРМ. Кроме того, в данной статье указаны научные подходы о возможностях использования доказательств, полученных в результате проведения ОРМ, а также способы включения в доказывание материалов, полученных в ходе ОРД, выделено и обозначено наличие общих и специальных требований к допустимости материалов ОРД, а также перечислены и подробно раскрыты общие требования допустимости указанных материалов.
Zinc Oxide Nanoflakes Mechanism of Action: A Future Prospective Nanomedicine Against CRE Infections
Authors: Brij Nandan Singh  , Harshada Shah  , Praful S Patil  , Mohammad Ashfaq  , Ankit Singh  , G. C. Upadhyay
Published: February 2023

The emergence and spread of carbapenem-hydrolysing beta-lactamases among Enterobacteriaceae and Non-fermentative Gram-negative bacilli organisms like Pseudomonas spp. or Acinetobacter baumannii over the past ten years is a serious problem in hospital settings. This problem has been exacerbated by the fact that carbapenems are no longer as effective against these pathogens. Aside from that, numerous bacteria in the natural environment form biofilms. When opportunistic biofilm-forming pathogens cause infections, they can cause severe symptoms in many cases and death in people who don't have strong immune systems. No new class of antibiotic have been reported in the last several decades. In this context, Recent years have seen a rise in the importance of nanobiotechnology in the production of nanomaterials that function as antibacterial agents. It is possible for nanoparticles to be active molecules or compounds that react with bacterial cells to kill them. This has the potential to resolve issues associated with multidrug resistance and inhibit biofilm. In the present study, synthesized ZnO nanoflakes were utilized. These nanoflakes had an average crystallite size of 21.5 ± 4.8 nm, a thickness of 20-50 nm, and different characteristics. We have included 67 Carbapenem resistant Enterobacteriaceae (CRE) and Non-fermentative Gram-negative bacilli isolates, which were isolated from various clinical samples. ZnO-NPs showed strong antibacterial and antibiofilm action against clinical isolates, according to growth kinetics and antibiofilm assay. In addition, we looked into how ZnO-NPs interact with clinical bacterial strains to determine their mode of action. ZnO is thought to exert its effects via reactive oxygen species (ROS) production, which boosts membrane lipid peroxidation and ultimately results in the loss of reducing sugars through membrane leakage. These findings suggest that in future ZnO-NPs might be an effective alternate treatment of choice to treat infections caused by CR bacterial isolates.
Positional Release Therapy And Its Application In Various Musculoskeletal Conditions: A Review Of Literature
Authors: Disha Shetty, Saumya Srivastava, Harramb Mittal
Published: February 2023

Introduction: Positional release is a type of manual therapy that can be used effectively in treating pain and disability that is associated with musculoskeletal conditions. This review's goal is to provide an overview of positional release therapy (PRT) and how it can be used to treat various musculoskeletal conditions.

Materials and Methods: The data source of this literature review was done by a comprehensive search of already published relevant articles from various medical databases. All studies where the positional release method of treatment was used as an intervention in treating musculoskeletal conditions were included. 21 articles in all were obtained from the electronic databases, of which 6 articles were selected to be included in this review.

Conclusion: PRT is demonstrated to be an effective intervention in treating various musculoskeletal conditions like neck pain, low back pain, hamstring tightness, and ankle sprain.
A Comparative Overview of Various Fungal Menaces Amidst Corona Virus Disease
Authors: Darshan J C, Medhini H Gowda, Sayantan Ghosh
Published: February 2023

The disastrous Coronavirus Disease outbreak declared as a global pandemic, has become a potential hazard to public health. The second wave of COVID-19 in India has been strongly linked to the rising cases of various fungal infections including mucormycosis, aspergillosis, candidiasis, and mucor septicus. These fungal infections have been a cause for alarm for the general public. The color-coding of the fungal infections is primarily based on the symptoms observed in the infected patients and not based on the color of the fungi itself. For busting the myths behind fungal infections, a comprehensive and deeper understanding of the facts is needed to overcome this challenge. Rapid diagnosis, reversal of underlying predispositions, surgical excision or debridement, and optimal antifungal therapy are some of the crucial factors in combating these fungal infections. This article provides a comparative review of literature on various fungal infections during COVID-19, that have been threatening worldwide, predominantly in India. A well-established databases literature search was conducted.