bluuebunny/crossref_metadata_2025 huggingface dataset:
Exercise intolerance in comorbid COPD and heart failure: the role of impaired aerobic function
Authors: Rocha Alcides , Arbex Flavio F. , Sperandio Priscila A. , Mancuso Frederico , Marillier Mathieu , Bernard Anne-Catherine , Alencar Maria Clara N. , O'Donnell Denis E. , Neder J. Alberto
Published: February 2019

Impaired aerobic function is a potential mechanism of exercise intolerance in patients with combined cardiorespiratory disease. We investigated the pathophysiological and sensory consequences of a low change in oxygen uptake (ΔV′O2)/change in work rate (ΔWR) relationship during incremental exercise in patients with coexisting chronic obstructive pulmonary disease (COPD) and systolic heart failure (HF).

After clinical stabilisation, 51 COPD–HF patients performed an incremental cardiopulmonary exercise test to symptom limitation. Cardiac output was non-invasively measured (impedance cardiography) in a subset of patients (n=18).

27 patients presented with ΔV′O2/ΔWR below the lower limit of normal. Despite similar forced expiratory volume in 1 s and ejection fraction, the low ΔV′O2/ΔWR group showed higher end-diastolic volume, lower inspiratory capacity and lower transfer factor compared to their counterparts (p<0.05). Peak WR and peakV′O2were ∼15% and ∼30% lower, respectively, in the former group: those findings were associated with greater symptom burden in daily life and at a given exercise intensity (leg discomfort and dyspnoea). The low ΔV′O2/ΔWR group presented with other evidences of impaired aerobic function (sluggishV′O2kinetics, earlier anaerobic threshold) and cardiocirculatory performance (lower oxygen pulse, lower stroke volume and cardiac output) (p<0.05). Despite similar exertional hypoxaemia, they showed worse ventilatory inefficiency and higher operating lung volumes, which led to greater mechanical inspiratory constraints (p<0.05).

Impaired aerobic function due to negative cardiopulmonary–muscular interactions is an important determinant of exercise intolerance in patients with COPD–HF. Treatment strategies to improve oxygen delivery to and/or utilisation by the peripheral muscles might prove particularly beneficial to these patients.
Signal-to-noise ratio enhancement for downhole microseismic data based on 3D shearlet transform
Authors: Li Juan , Li Yuan , Ji Shou , Li Yue , Qian Zhihong
Published: February 2019

Downhole microseismic data are characterized for their high frequency and small amplitude, which bring great difficulty for noise suppression. We present a random noise attenuation method for downhole microseismic data based on the 3D shearlet transform (3DST). In contrast to the 2D shearlet, 3DST takes into account the correlation among three components of downhole microseismic. With the help of correlation among the data, downhole microseismic data are reassembled into a new 3D matrix and then transformed to the shearlet domain. After the analysis of the coefficients’ energy and the high-order cumulant on each scale, an efficient threshold function is proposed. We apply a small threshold to the coefficients associated with the signal’s scales, and a large threshold is chosen for the scales of the noise. Experimental results indicate that the algorithm significantly improves the signal-to-noise ratio of the microseismic data and effectively preserves a valid signal.
Nebulized Lidocaine in the Treatment of Refractory Postoperative Laryngospasm: A Case Report
Authors: Oon Zhihao , Ha Chiew-Bing , Sicinski Marcin
Published: February 2019

Intraoperative laryngospasm occurs in <1% of cases. Recurrent laryngospasm is rarer. Some risk factors include shared airway and pediatric surgery, secretions, pungent volatile anesthetics, and patient factors, such as smoking and asthma. Conventional management includes the application of positive airway pressure, jaw thrust, the removal of any offending stimuli, deepening anesthesia, or administering muscle relaxants. Nebulized lidocaine is used to anesthetize the vocal cords before awake fiberoptic intubation. This case highlights the novel use of nebulized lidocaine to successfully treat refractory postoperative laryngospasm in a fully conscious adult patient after conventional measures were unsuccessful.
Case Report: Unprovoked venous thromboembolism in a young adult
Authors: Dhabhar Jeyhan , Mehta Varshil , Desai Nimit , Dawoodi Sameer , Zaman Sojib Bin
Published: February 2019

A 24-year-old male was presented to us with sudden onset of chest pain and dyspnea for the past one hour. There was no history of calf pain, trauma, surgery, prolonged immobilization, long-haul air travel, bleeding diathesis or any other co-morbidity. The patient denied any addiction history. The Electrocardiogram showed tachycardia with S1Q3T3 pattern. The left arterio-venous Doppler study was suggestive of a thrombus in popliteal vein and sapheno-popliteal junction. The CT-Pulmonary Angiogram scan was suggestive of a massive pulmonary thromboembolism. The patient was thrombolysed with Intravenous Alteplase immediately and was put on tab Rivaroxaban for maintenance. He was later discharged after being stable.

Unprovoked venous thromboembolism (VTE) is very rare and has the potential to lead to pulmonary embolism which could be disastrous, especially in young adults. We present such a case where unprovoked VTE was diagnosed and treated. This case suggests that high clinical suspicion is the key for the diagnosis of acute pulmonary embolism, especially in the absence of history suggestive of deep vein thrombosis.
Saccular Aneurysms of the Transverse Aortic Arch
Authors: Preventza Ourania , Coselli Joseph
Published: February 2019

Based on a Presentation at the 2013 VEITH Symposium, November 19–23, 2013 (New York, NY, USA)

Saccular aneurysms of the aortic arch, whether single or multiple, are uncommon. The choice of repair technique is influenced by patients' comorbidities and age. Repairing saccular aneurysms with traditional open techniques can be technically demanding; therefore, endovascular technology and a variety of hybrid approaches have been developed to facilitate such repairs and, potentially, to improve clinical outcomes, especially in high-risk patients. There have been no large, randomized studies to compare the outcomes of these different treatment options in patients with single or multiple saccular aneurysms of the arch. In this review, we outline the etiology and common locations of these aneurysms, the different open, completely endovascular, and hybrid techniques used to treat them, and the treatment selection process.
Acute Bilateral Lower Extremity Paralysis Secondary to Acute Thrombosis of an Infrarenal Abdominal Aortic Aneurysm
Authors: Watson T. Joseph , Childers W. Kurtis , Haga Lindsey , Calaitges John
Published: February 2019

We present the case of a 64-year-old male who presented to the emergency department with bilateral limb ischemia and paralysis for approximately 1 hour. Computed tomographic angiography demonstrated occlusion of the infrarenal aorta beginning just above the patient’s known abdominal aortic aneurysm (AAA) and extending into both common iliac arteries. He was emergently treated via open repair of the AAA with a Gore-Tex tube graft, bilateral common iliac thrombectomies, and bilateral lower extremity four-compartment fasciotomies. Post-operatively, he had monophasic signals in both posterior tibial arteries, neither of which was present before the operation. During recovery, he developed an ileus but otherwise did not have complications. He was discharged to rehabilitation on post-operative day 15.
Left Ventricular Intussusception of an Intimal Flap in an Aortic Dissection Stanford Type A
Authors: Kaufeld Tim , Shrestha Malakh , Haverich Axel , Martens Andreas
Published: February 2019

A 75-year-old woman was admitted to the emergency department with severe and sudden chest pain. Transthoracic echocardiogram showed an unusual case of aortic dissection Stanford Type A with complete circumferential detachment of the ascending aorta intima. An intussusception of the intima flap into the left ventricular outflow tract was also observed. This case presents a very rare surgical treatment involving root repair using tissue adhesives for a left ventricular intimal flap.
Research roundup: February 2019
Authors: Austin Yasmin , Seal Joanne , Shannon Jennifer
Published: February 2019

In this section, a range of brief synopses of recently published articles that may be of interest to health visitors is presented. The aim of this roundup is to provide an overview, rather than a detailed summary, of the research papers selected. Should you wish to look at any of the papers in more detail, a full reference is provided.
Newly qualified health visitor: What is the latest advice on alcohol and breastfeeding?
Authors: Bewick Jessica
Published: February 2019

Breastfeeding and alcohol consumption is a topic often raised by parents who report being left with more questions than answers, even after receiving advice from both social peers and professionals
Relationships and sexuality education for children with special educational needs and disabilities
Authors: Reynolds Kate E
Published: February 2019

Children with special educational needs and disabilities (SEND) comprise about 14.6 % of pupils in England. Research shows that aspects of relationships and sexuality education (RSE), both formally and informally, have tended to be low priority for professionals and parents of these children. Proposed government changes to RSE policies in all schools in England will take effect from September 2020. Studies identify RSE as having a potential role in reducing sexual abuse and tackling structural inequalities, which children with SEND experience. Health visitors are in a key position to identify potential barriers to RSE learning in the home, strategies to overcome these and possible referrals for professional support. This article focuses on the current research into some of the issues for parents of children with SEND, the challenges for such children and how health visitors can enable parents to teach informal RSE to their children.
Feasibility Study on Rapid Analysis of Doxycycline Hydrochloride Aqueous Solution by Terahertz Time-Domain Spectroscopy
Authors: Huang Yuxin , Wang Chen , Qin Jianyuan , Xu Wendao , Chen Min , Du Jianxiang , Xie Lijuan , Ying Yibin
Published: February 2019

Abstract. Antibiotics have been extensively applied in the treatment of infections in food-producing animals. However, the residues of these agents create a potential risk to human health. Among the methods available for rapid detection of antibiotics, terahertz time-domain spectroscopy (THz-TDS) has emerged as a technique with unique advantages over other methods. In this study, we demonstrate that rapid analysis of doxycycline hydrochloride (DCH) aqueous solutions could be achieved with THz-TDS through transmission, attenuated total reflection (ATR), and reflection with minimum detectable concentrations of 5000, 10, and 80 mg L-1, respectively, indicating that the ATR and reflection methods are superior to the transmission method for low-concentration aqueous solutions. This study is an effort to promote the development of rapid analysis of antibiotic residues in an aqueous matrix using THz spectroscopy. Keywords: Attenuated total reflection, Doxycycline hydrochloride solution, Reflection, Terahertz, Transmission.
Una aproximación a la construcción de la identidad étnica en migrantes africanos en la Patagonia norte: Un estudio comparativo
Authors: Kalmbach Jonas
Published: February 2019

Este artículo propone una aproximación exploratoria a la construcción de la identidad étnica de los migrantes provenientes del África subsahariana que actualmente se encuentran en la Patagonia norte, protagonizando un nuevo «flujo migratorio» que trasciende los grandes centros urbanos. A través de un enfoque comparativo, buscamos restituir la heterogeneidad de experiencias y autonarrativas migratorias, analizando las relaciones intra e interétnicas en la sociedad de destino. Esto nos permitió distinguir una modalidad de «migración transnacional», comprender las comunidades étnicas como «territorios móviles» y aproximarnos a la «alterización» radical de los migrantes enraizada en el imaginario de una Argentina blanca y europea.

Palabras claves: Etnicidad, migración transnacional, territorios móviles, religión, exotización.
Beyond the Boy Scout's sleeve: a personal review of ethical certification
Authors: Wright Simon
Published: February 2019

This article reviews the history of third-party ethical certification of food and drink, concentrating mainly on organic and Fairtrade. The strengths and weakness of the approaches taken to date are reviewed. The author includes his personal experience of such schemes gained over the last thirty years. From this, he concludes that third-party certification has not delivered sufficient benefits to producers. He notes the challenge posed by new schemes designed and owned by large food processors and multiple retailers. The article concludes that it may be better to think of third-party certification as a first step rather than a destination.
Antibiotic resistance: A cross-sectional study on knowledge, attitude, and practices among veterinarians of Haryana state in India
Authors: Parkunan Thulasiraman , Ashutosh Manju , Sukumar Bharathy , Chera Jatinder Singh , Ramadas Sendhil , Chandrasekhar B. , Ashok Kumar S. , Sharma Rachana , Santhosh Kumar M. , De Sachinandan
Published: February 2019

Aim: The current study aimed to assess the knowledge, attitude, and practices pertaining to antibiotic usage among the field veterinarians who serve as nodal officers playing a crucial role in disseminating knowledge to the farmers regarding livestock management practices in India.

Materials and Methods: A pilot study was conducted in which 106 of the 173 field veterinarians of Haryana, India, agreed to contribute through their valuable participation in the study. The collected data were critically analyzed by simple descriptive statistics, and the responses were ranked using Garrett's ranking method.

Results: Our study found that most of the clinicians were aware of the fundamental clinical aspects of antibiotic resistance (AR), i.e., the general causes and transmission of resistance, response during treatment failure, and safe disposal of hospital waste. Further, implementation of "antibiotic stewardship" (rational/responsible use of antibiotics) and interruption of AR transmission by means of cross-kingdom pathogens are two ways to restrict the spread of resistant pathogens which were not in the clinical purview of majority of the clinicians. This highlights a lack of awareness and scope of improving clinician's knowledge pertaining to AR. Moreover, we got to know the methodology adopted by farmers for disposal of infected milk from diseased udders as well as their attitude toward diseased and unproductive animals.

Conclusion: This study provides snippets of the current animal husbandry practices prevalent at the field level which would assist to plug in the gaps of knowledge regarding AR among the veterinarians as well as the general public and serve to reduce its deleterious impacts in Indian animal farming as well as in the world through the concept of "One World, One Health."
Levantamento e análises das fontes alternativas de captação de água utilizadas no abastecimento de uma população rural de Visconde do Rio Branco – MG
Authors: Rodrigues Áureo Lucio , Melo Lidervan Paula , Souza Waltencir Balbino , Lima Luana Cristina , Souza Débora Castro
Published: February 2019

A qualidade de vida dos seres humanos está diretamente relacionada à água, a qual é utilizada principalmente para ingestão direta, preparo de alimentos, higiene pessoal e de utensílios. Geralmente a população da zona rural não é beneficiada com obras de saneamento básico, e por isso sofre com a falta de fontes seguras de abastecimento de água e com descarte de dejetos e diversos tipos de resíduos. O presente trabalho teve como objetivo realizar um mapeamento das fontes alternativas para captação e abastecimento de água em uma comunidade rural do município de Visconde do Rio Branco-MG e análises de algumas amostras coletadas dessas fontes, a fim de compará-los com os valores máximos permitidos pela Portaria Nº 2.914/2011 do Ministério da Saúde. Foram quantificadas 39 fontes alternativas, dentre poços semiartesianos, minas e cisternas, das quais foram selecionadas 6 fontes para coleta das amostras. Os resultados das análises realizadas encontraram contaminação para coliformes totais em todos os 6 pontos de coleta, coliformes termotolerantes em 1 dos pontos e valores acima da concentração permitida para ferro total em 3 pontos. Para Ferro Total, dois dos três pontos contaminados são minas localizadas em terrenos do tipo aluvião, onde é comum encontrar ferro na forma de bicarbonato ferroso dissolvido na água; o outro ponto contaminado (cisterna) teve como fonte de contaminação, revestimentos ferrosos em parte da tubulação e na bomba de captação.
Influência do lençol freático na condutividade elétrica e PH em cemitério
Authors: Veloso Soares Rosa Maria Clara , Ernesto Ucker Fernando
Published: February 2019

O sepultamento de corpos humanos em locais sem tratamento e infraestrutura adequada pode impactar o solo e o lençol freático através da infiltração e percolação do necrochorume, visto que estando o lençol freático em contato com a pluma de contaminação ocorre a solubilização dos íons presentes no necrochorume o que favorece o enriquecimento de sais, alterando assim a qualidade da água subterrânea. Por este motivo, o objetivo deste estudo foi avaliar o nível do lençol freático na condutividade elétrica e no pH sob influência de um cemitério na região metropolitana de Goiânia (GO). Portanto, foram construídos cinco poços de monitoramento, dos quais levou-se em consideração a declividade do terreno. Após isto realizou-se a coleta da água subterrânea com tubos bailers, bem como o monitoramento do lençol freático entre os meses de março a agosto de 2018, realizou-se em laboratório a análise dos parâmetros de condutividade elétrica e pH das amostras de água dos poços de monitoramento, conseguinte os dados foram inseridos no programa Excel (2013) para confecção dos gráficos. Os resultados obtidos demonstraram que o nível do lençol freático influencia na condutividade elétrica e pH devido as variações da condutividade elétrica e acidificação do pH, sendo assim um indicativo da contaminação da água subterrânea por necrochorume.
Brain Fatigue is a Critical Issue
Authors: Habibzadeh Nasim , Wood Daniel
Published: February 2019

The brain is one of the most complicated body segments which processes almost all activities in human body. Excessive physical and mental overloads can cause brain fatigue and may put the brain health at risk of various disorders. Strategies such as reducing the workloads and performing mediation and walking provide opportunities for brain to relax and reconstruct its capability again.
Non-Hodgkin Lymphoma of External Auditory Canal – Uncommon Location and Related Risk Factors
Authors: A D Mettias Bassem A D , Zeitoun Hisham
Published: February 2019

Objective: Presentation of rare case report of primary non-Hodgkin Lymphoma of temporal bone secondary to immunodeficiency after prolonged steroid administration in a diabetic patient. Then review the literature of similar case reports. Method: 49 years old female presented with hearing loss, facial paralysis and otalgia. Biopsy revealed high grade non Hodgkin’s B-lymphoma. She underwent chemotherapy and had remarkable response. Result: Rapidly progressive deafness, facial paralysis and otalgia are common presentations of external canal Non-Hodgkin lymphoma. The disease is common in middle age, females and has a fair response to chemotherapy, good to radiotherapy. Surgery is an alternative method in isolated lesions or recurrent cases. Conclusion: High dose steroid and type II diabetes are potential risks for acquired immunodeficiency. External Auditory canal lymphoma is uncommon sequel. Chemotherapy is very effective in treatment of isolated cases without B symptoms
Lingual Cyct
Authors: Fattni Mohammad , Madan Fakhria , Refai Asma , Bador Kalid , Alhojaili Najia
Published: February 2019

Epidermoid cysts encountered throughout the body, only 7% occurs in the head and neck area, with the oral cavity accounting for only 1.6%. Intraoral this benign slow growing and painless entity is usually located in the submandibular, sublingual and sub mental region. They can cause symptoms of dysphagia and dyspnea and have a malignant transformation potential. Surgical excision is the treatment of choice. Described here is a case of gigantic sublingual cyst.
A Pilot Trial of Applying Geographic Information System Technology to Health System Strengthening in the Upper East Region of Ghana
Authors: Asuo-Mante Eric , Mumuni Abdul-Jaleel , Asuo-Mante Myriam , Yelifari Lawrence , Awoonor-Williams John Koku , Phillips James F.
Published: February 2019

Despite widespread use of Geographic Information System (GIS) technology to strengthening health systems, the application of GIS to health systems strengthening in resource-poor Sub-Saharan Africa remains rare. Over the June 2012 to December 2013 period, the Ghana Health Service (GHS) conducted a pilot application of GIS to health systems development in one rural impoverished district of the Upper East Region (UER). Workers were deployed to gather coordinates of health care facilities throughout the UER. Coordinates were linked to routine health information data, and utilized to generate maps for guiding task prioritization. For example, geocoded Community-based Management of Severe Acute Malnutrition (CMAM) program data were used to target services in communities where the prevalence of childhood acute malnutrition was relatively high. GIS was pivotal in tracking and responding to infectious disease morbidity from causes such as diarrheal diseases and tuberculosis. UER Regional Health Administration (RHA) authorities are currently utilizing GIS to map antenatal care coverage, skilled birth deliveries, neonatal mortality, still births, family planning service caseloads as well as for targeting programmatic action. Experience emerging from this trial attests to the value of GIS in contributing to efforts to strengthen health systems in rural impoverished regions of Africa.
The Birth of Endowiki, An Italian Online Platform for Continuous Medical Education In Endocrinology
Authors: Attanasio Roberto , Gualano Luca , Misischi Irene , Caprioli Silvia , Papini Enrico , Toscano Vincenzo , Garofalo Piernicola
Published: February 2019

Background
Conventional tools for medical education are burdened by many drawbacks. Textbooks become rapidly outdated, meeting attendance is expensive, and results reported in journals are not easily suitable for clinical practice. Uptodate and Endotext are excellent online tools, but they have been developed for a clinical context far different from that of our country.

Methodology
Italian Association of Clinical Endocrinologists (AME) charged a task force aiming to develop an educational tool specifically tailored for Italian clinical endocrinologists. Required characteristics were clinical approach, modularity, continuous updating, full online availability (even by mobile devices), open sections and sections for registered members only, opportunity for individualization, indexing and search engine to facilitate browsing. Starting from an open-source platform, Joomla, several changes were implemented.

Results
Three editors, 2 central editorial secretaries, 30 section coordinators and over 350 authors have been involved in the writing of 21 different sections covering all fields of endocrine and metabolic diseases. The access to Endowiki is free for AME members and is fully open in sections for patients. All readers are requested to serve as referee, pointing to mistakes and need for revision. The system is attended daily by a mean of 250 individuals.

Conclusions
Endowiki stands alone as an opportunity for medical education in Italy. The big challenges will be the continuous updating and the link to the national certified system for CME.
Metodología para la realización de un diagnóstico de la gestión de indicadores ambientales en la administración pública
Authors: Miranda Cuéllar Roani Ladislá , Reyes Acuña Soidelys , Gómez País Gloria de las Mercedes , Goicochea Cardoso Odalys Caridad
Published: February 2019

Proteger el medio ambiente es una preocupación a nivel internacional que ha ido cobrando fuerzas a todos los niveles. Para ello las organizaciones requieren que la toma de decisiones se lleve a cabo basada en la evidencia, razón por la que la información y su gestión adecuada son imprescindibles, soportadas en indicadores, que propician el seguimiento y control. El objetivo de este trabajo es diseñar una metodología para el diagnóstico de la gestión de los indicadores. Se utilizaron los métodos: análisis-síntesis e hipotético-deductivo, se emplearon instrumentos tales como: entrevistas, encuestas y cuestionarios, consulta a especialistas; método de Delphi y métodos estadísticos. Se aplicó la metodología a los indicadores ambientales nacionales y se detectaron vacíos en la información y en el marco legal, así como otras insuficiencias en la gestión de los indicadores que inciden en la toma de decisiones.
Comparación de las dos metodologías de análisis y diseño más recientes de ASCE 7, para el análisis de su posible empleo en edificaciones con aislamiento sísmico de base en Colombia
Authors: Piscal Arevalo Carlos Mario , Lopez Almansa Francisco
Published: February 2019

El aislamiento de base es una técnica de protección sismorresistente para edificaciones, con un uso exitoso y amplio a nivel mundial. En Colombia actualmente existen algunos edificios que incorporan esta técnica, los cuales fueron diseñados bajo los requisitos de normativas americanas vigentes en la época, como ASCE 7-10. Dicha normativa ha sido recientemente actualizada a su versión 2016, con importantes cambios técnicos respecto a su predecesora. ASCE 7-16 incorpora resultados de las investigaciones más recientes en cuanto a aislamiento sísmico se refiere, por ende las futuras edificaciones que emplean esta técnica y que sean diseñadas y construidas en el país deberían seguir dicho documento. Es por todo lo anterior que en el presente trabajo se evidencia la necesidad de hacer un análisis de la nueva filosofía de diseño para edificaciones con aislamiento de base y discutir su aplicabilidad en el país.
PEMBANGUNAN DAERAH PERBATASAN YANG TERABAIKAN: KAJIAN PERBATASAN KECAMATAN RUPAT UTARA KABUPATEN BENGKALIS – SELAT MALAKA
Authors: Al Hafis Raden Imam
Published: February 2019

Dengan bergulirnya pemerintahan dari yang awalnya sentralistik bertransformasi menjadi desentralisasi merupakan suatu keuntungan bagi daerah, terutama bagi kabupaten yang jauh dari jangkauan pemerintahan pusat. Harapan terbesar bagi daerah dengan adanya desentralisasi ini terutama bagi daerah perbatasan adalah pembangunan yang adil serta merata, terciptanya kesejahteraan tanpa ada keberpihakan pembangunan bagi setiap daerah yang hal tersebut diatur dalam Undang-Undang Nomor 23 Tahun 2014 tentang pemerintahan daerah. Namun harapan dan keinginan masyarakat tersebut tidak terjadi disebagian daerah, khususnya di Kecamatan Rupat Utara Kabupaten Bengkalis yang notabennya adalah salah satu kabupaten terkaya di Indonesia yang menghasilkan minyak bumi dan sebagian besar Pendapatan Asli Daerahnya disumbangkan bagi pembangunan Negara Republik Indonesia. Untuk itu, kajian dalam tulisan ini membahas bagaimana hal tersebut terjadi di tengah negeri yang mempunyai kebijakan desentralisasi. Penyelesaian permasalahan daerah perbatasan Kecamatan Rupat Utara Kabupaten Bengkalis akan bisa dipecahkan apabila: 1. Adanya “political will” dari pemerintah itu sendiri; 2. Mengenali dan mengkaji secara mendalam mengenai potensi wilayah dan local wisdom yang ada; 3. Memahami sosial-ekonomi serta sosial-budaya penduduk setempat; 4. Mengidentifikasi ketersediaan sarana dan prasarana untuk kegiatan pelayanan publik bagi masyarakat setempat; dan 5. Kebijakan pembangunan daerah perbatasan serta perumusan strategi pengembangan yang sesuai dan lokalita serta berkoordinasi dan bersinergi dengan antara pusat dan daerah agar tidak terjadi tumpang tindih program dan pada akhirnya dapat menjadi sebab terhambat dan lambannya pembangunan.
DILEMA KEBIJAKAN RELOKASI PEDAGANG KAKI LIMA (PKL) KE PASAR BLAURAN II KOTA SALATIGA
Authors: Thoriq M. Isa , Samsudin Muchamad
Published: February 2019

The informal sector contributes greatly to the nation's economic development. Among the various forms of economic activity in this sector are street traders (PKL). The existence of street traders in various places has driven the economy of the community, but without good management, it will cause problems. The city of Salatiga as one of the cities in Central Java has an attraction for street traders, the existence of street traders in this city has experienced ups and downs due to the socio-economic conditions of the community. The government always regulates and manages the existence of street traders. In this case, the City Government of Salatiga through the Trade Office relocated street vendors who were on “Jalan Taman Pahlawan” to Blauran II Market. This study uses a qualitative descriptive method that looks at the problem of formulation of street traders relocation policy. Based on the conclusions of the results of this study that the incremental model of the formulation of street traders relocation has a direct impact on the street traders and the construction of Blauran II Market.
KEBIJAKAN PEMBANGUNAN DESA MELALUI PEMBANGUNAN INFRASTRUKTUR TRANSPORTASI DALAM UPAYA PEMERATAAN PEMBANGUNAN DI DESA PLESUNGAN KECAATAN KAPAS KABUPATEN BOJONEGORO
Authors: Rahman Amni Zarkasyi , Novitasari Diyah
Published: February 2019

Law of Republic Indonesia Number 6 of 2014 concerning Villages as one of development policy raises an implication in the budgeting system, namely the emergence of The Village Funds (VF) and Village Fund Allocation (VFA) in the components of the Village Budget (APBDes). One of the objectives of the Village Law through VF and VFA is to ensure that basic infrastructure such as roads, canals, dikes, electricity and clean water in the village have been fulfilled so as to be able to support the smooth economic activities of the village. The road which is one of the basic infrastructure related to transportation and accessibility is key in the economy of a region. The existence of a good road facilitates access to an area and the community can more easily carry out their activities. This will certainly have a long-term impact on people's lives, one of which is increasing economic growth in the region, one of which can be seen with an increase in Gross Regional Domestic Product (GRDP). The important thing to study more deeply is how the availability of good road facilities in the village is able to contribute to the increase in GRDP.
PENGARUH KUALITAS PELAYANAN, DAYA SAING DESTINASI DAN PENGALAMAN SEBELUMNYA TERHADAP KEPUTUSAN BERKUNJUNG KEMBALI DENGAN KEPUASAN PENGUNJUNG SEBAGAI VARIABEL INTERVENING
Authors: Pallefi Alvira Zulva , Tanto Widiar
Published: February 2019

The aim of this study is to measure the influence of service quality, destination competitiveness, and previous experience toward revisit decision trough tourist satisfaction. The population of this resarch is visitors of Goa Kreo, while the sample is 100 visitor of Goa Kreo with some certain prerequirements. The data was analyzed using two-step analysis with SPSS 17.0 for windows where the validity test, reliability test,doefficient of correlation, coefficient of determination, test of significance (t-test and f-test) in advance has been done before.The result of this study is showing that service quality, destination competitiveness and previous experience has positive impact toward visitor satisfaction, where the biggest impact is own by previous experience. Based on the result of two-step analysis, tourist satisfaction is an intervening variable toward revisit decision in this study.Some recomendations are added based on those result. It’s recomended that hygine, security, and hospitality in Goa Kreo must be incerased. Moreover, it’s neccesary to increase destination competitiveness like facility’s maintenance and added up some general facility so that visitor will be satisfied with their experiences and willing to come back to Goa Kreo.
RISK PROFILE, GOOD CORPORATE GOVERNANCE, EARNING, CAPITAL (RGEC) METHOD SEBAGAI INSTRUMEN PENGUKUR TINGKAT KESEHATAN PERBANKAN SYARIAH DI INDONESIA
Authors: Kusnanto Amir
Published: February 2019

Bank Indonesia perfected the Bank's health assessment method from CAMELS to RGEC method which includes factors of Risk Profile, Good Corporate Governance, Earning, and Capital in accordance with Bank Indonesia Circular Letter No.13 / 24 / DPNP dated October 25, 2011 on Assessment Health Level of Commercial Banks. Such adjustments need to be made so that the bank soundness rating can be more effectively used as a tool to evaluate the bank's financial performance. The results of the analysis on the Rating of Health Level at Bank Syariah Mandiri, Bank BRI Syariah, Bank Syariah Bukopin, BCA Syariah using RGEC method shows the bank's health predicate in accordance with the standards set by Bank Indonesia for the period 2013, 2014 and 2015 with the conclusion of the assessment results the same in composite 2, which reflects the general condition of the bank healthy. Except for Bank BNI Syariah in the period of 2013 with the conclusion of composite rating of 1, which reflects the condition of banks that are very healthy, the period 2014 and 2015 with the conclusion of composite rating 2, which reflects the general condition of the bank  healthy. The Bank's Health Level in terms of RGEC at Sharia Commercial Banks in the period of 2013, 2014, and 2015 are in healthy criteria, so it is considered very capable of facing significant negative impacts from changes in business conditions and other external factors.
Lexical richness of Chinese candidates in the graded oral English examinations
Authors: Zhang Jian , Daller Michael
Published: February 2019

The main purpose of this study is to explore the lexical richness of Chinese candidates of different proficiency levels in a graded examination in spoken English (GESE), which is an exam developed by Trinity College, London and administered in Beijing, China by trained local examiners. We compared 5 lexical indices and the mean length of utterances (MLU) of the GEGE candidates of three proficiency levels. The quantitative results first indicate that lexical richness plays an important role in these oral interviews and there are significant correlations between the lexical indices, the MLU and the proficiency level of the candidates. Furthermore, candidates who pass the oral exams have significantly higher scores for lexical richness. There are significant differences between the lexical richness scores at the Initial level (GESE Grade 2) and at the Elementary level (Grade 5). But only some measures show significant differences between the Elementary level (Grade 5) and the Intermediate level (Grade 7), which casts some doubt on the validity of the classification system. One reason for this result might be the fact that a Grade 7 certificate leads to higher chances in the admissions process for prestigious secondary schools and there is a strong interest by candidates and by private preparatory schools to get a certificate at this level. Some candidates might have enrolled on this level without meeting the criteria fully. Overall, our results show that measures of lexical richness and MLU are good predictors for success in oral interviews, but that factors other than proficiency play a role when it comes to the placement of students in Grade 7. The unique contribution of the present study resides in the fact that we use a large sample drawn randomly from a huge corpus of oral interviews. On this basis, we can gain further insights in the role that vocabulary knowledge plays in oral interviews.
Evaluation of procalcitonin immunoassay concordance near clinical decision points
Authors: Chambliss Allison B. , Hayden Joshua , Colby Jennifer M.
Published: February 2019

Background

Procalcitonin (PCT) is a biomarker for systemic bacterial infections and may aid in decision making for antimicrobial stewardship. Numerous PCT assays are available on common clinical immunoassay platforms. However, questions remain about the harmonization of these assays and whether the same clinical decision points may be used with all methods.

Methods

Thirty-seven remnant patient serum samples were analyzed across four different PCT assays: Abbott ARCHITECT i2000, bioMérieux MINI VIDAS, Roche Elecsys cobas e 411, and BRAHMS KRYPTOR. Regression analysis was performed, and correlation was assessed at common clinical decision points for antimicrobial therapy: 0.10, 0.25, and 0.50 μg/L.

Results

Data showed a positive bias of the MINI VIDAS compared to the KRYPTOR (slope=1.188, R=0.9873) and negative biases of both the ARCHITECT i2000 and cobas e 411 compared to the KRYPTOR (slope=0.806, R=0.8864, and slope=0.795, R=0.8974, respectively). A comparison of results at commonly used clinical decision points for antimicrobial stewardship showed that, relative to the KRYPTOR, 21% of samples would be classified into different interpretive categories by the ARCHITECT i2000 method, 31% of samples would be classified differently by the MINI VIDAS method, and 16% of samples would be classified differently by the cobas e 411 method.

Conclusions

All methods showed reasonable analytical agreement; however, an analysis of result interpretation at clinical decision points showed that many samples were differentially categorized (e.g. shifted by one interpretive category) by the methods. Overall, our findings support a need for harmonization of PCT methods. Until then, institutions should independently evaluate their PCT assays against predicate methods and consider the impact on result interpretation prior to incorporating PCT into clinical practice.
How do Institutions Inspire Ambitions? Differentiating Institutional Effects on Entrepreneurial Growth Intentions: Evidence from China
Authors: Li Yaokuang , Wang Jing , Long Dan
Published: February 2019

Entrepreneurial growth intention, as an outcome of the entrepreneur’s cognition, has been found to be influenced by the institutional context. However, the cognitive rationale for the institutional impact on entrepreneurial growth intention is still unknown. This article builds upon the framework of institutional theory to reveal how the perceptions of institutional environment foster entrepreneurial growth intention via the entrepreneur’s specific cognitive process. Based on an extended model of the theory of planned behavior, we find that perceptions of different institutional dimensions exert important but distinct influence on the way in which entrepreneurs view and perceive venture growth and then indirectly inspire their ambitions in the post-entry stage of entrepreneurship. The entrepreneur’s perception of behavioral control plays a key role in this process. The implications for entrepreneurial practice and future research are then discussed.
Reconfigurable Graphene Circular Polarization Reflectarray/Transmitarray Antenna
Authors: Li Wen Tao , Sun Shunlai , Qi Nana , Shi Xiaowei
Published: February 2019

Reconfigurable reflectarray/transmitarray antennas have found broad applications in wireless communication due to their low cost, small size, flexible design, and superior performance. However, one common drawback of most current designs is the complex reconfiguration operation, which restricts their further applications. In this research, a new design strategy for reconfigurable reflectarray/transmitarray antennas is proposed and shown. Specifically, a circularly polarized
$11 \times 11$ unit-cell graphene-based reflectarray/transmitarray antenna covering an area of
$1.1 \times 1.1$ mm2 is designed, with a graphene-based frequency selective surface (FSS) as a ground. By adjusting the electric field, a dynamic change in the complex conductivity of graphene is achieved, which in turn changes the phase and the resonance point of the reflected or transmitted wave at the element. By tuning the size of the patch and changing the chemical potential of graphene, the element of the reflectarray/transmitarray operated at 1 THz can provide a dynamic phase range of more than
${360^ \circ }$. The simulation results show that the designed antenna can be dynamically reconfigured between the circularly polarized reflectarray/transmitarray antenna of the single structure, and has potential applications in emerging terahertz communication systems.
Behcet’s disease and pregnancy: obstetrical and neonatal outcomes in a population-based cohort of 12 million births
Authors: Lee Seohyuk , Czuzoj-Shulman Nicholas , Abenhaim Haim Arie
Published: February 2019

Background

Behcet’s disease (BD) is a rare, multi-systemic inflammatory disorder for which only limited and contradictory data exists in the context of pregnancy. Our objective was to estimate the prevalence of BD in pregnancy and to evaluate maternal and fetal outcomes associated with pregnant women living with BD.

Methods

Using the 1999–2013 Healthcare Cost and Utilization Project-Nationwide Inpatient Sample from the United States, we performed a population-based retrospective cohort study consisting of pregnancies that occurred during this time period. ICD-9 codes were used to identify delivery admissions to women with or without BD. Multivariate logistic regression was used to estimate the adjusted effects of BD on maternal and fetal outcomes.

Results

Among the 12,592,676 pregnancies in our cohort, 144 were to women with BD, for an overall prevalence of 1.14 cases/100,000 births between 1999 and 2013. Over the study period, the prevalence of BD rose from 0.5 to 2.4/100,000 births. Women with BD demonstrated a two-fold greater frequency of non-delivery hospital admissions during pregnancy, and were more likely to be Caucasian, have private medical insurance, be of the upper income quartiles, and deliver at an urban teaching hospital. Women with BD were at greater risk for preterm labor and postpartum venous thromboembolism, while their newborns were more likely to be born premature.

Conclusion

BD-associated pregnancies are increasing in prevalence and are associated with a greater risk for adverse maternal and fetal outcomes in pregnancy. Appropriate thromboprophylaxis during pregnancy should be considered given the increased risk for venous thromboembolism.
Twin anemia-polycythemia sequence and routine monitoring practices amongst maternal-fetal medicine specialists in the United States: an initial investigation
Authors: Nicholas Lauren D. , Fischbein Rebecca L. , Bhamidipalli Surya S.
Published: February 2019

Background

The purpose of this initial investigation was to begin to understand the routine twin anemia-polycythemia sequence (TAPS) monitoring practices of maternal-fetal medicine specialists (MFM specialists) in the United States in the absence of a formal guideline.

Methods

This study used an anonymous, online survey of 90 MFM specialists who were practicing in the United States. A $5 gift card to an online store was used to incentivize participants. Descriptive statistics were calculated.

Results

All MFM specialists reported at least some familiarity (100.00%) with TAPS. Most participants (92.94%) were familiar with methods for monitoring patients for TAPS and nearly all (97.50%) responded that they use ‘Doppler MCA-PSV’ to make a prenatal TAPS diagnosis. Nearly two-thirds of MFM specialists surveyed (65.06%) reported performing regular TAPS monitoring for patients with monochorionic-diamniotic (MCDA) pregnancies.

Conclusion

Despite no formal guidelines, the majority of American MFM specialists surveyed are using routine TAPS screening in their management of MCDA twin pregnancies, suggesting that the MFM specialists included in this study consider it a valuable diagnostic tool. Future research should further explore this possible trend toward routine TAPS monitoring amongst MFM specialists in the United States, as well as the potential value of routine TAPS monitoring in MCDA pregnancy.
Neurological development may be accelerated in growth-restricted fetuses: a 4D ultrasound study
Authors: Mori Nobuhiro , Kanenishi Kenji , AboEllail Mohamed Ahmed Mostafa , Nitta Emiko , Hata Toshiyuki
Published: February 2019

Objective

To assess whether neurological maturation and development are accelerated in fetal growth restriction (FGR) in utero using four-dimensional (4D) ultrasound.

Methods

The facial expressions of 50 appropriate-for-gestational-age (AGA) and 34 FGR fetuses aged between 28 and 35 gestational weeks were assessed using 4D ultrasound. Subsequently, they were differentiated into two gestational age groups (19 aged 28–31 weeks and 31 aged 32–35 weeks in AGA, and 15 aged 28–31 weeks and 19 aged 32–35 weeks in FGR). Fifteen-minute recordings were made, and the frequencies of seven facial expressions during that time were examined. Correlation analysis was conducted to assess the changing number of significant correlations with advancing gestation in each group.

Results

Out of 21 combinations of facial expressions at 28–31 and 32–35 gestational weeks in AGA fetuses, there was only three significant correlations. Similarly, only one was noted out of 21 combinations at 28–31 gestational weeks, but there were seven significant correlations in FGR fetuses at 32–35 weeks (P=0.018). However, there was no significant difference in the number of correlations of facial expressions between AGA (3/21) and FGR (7/21) fetuses at 32–35 weeks of gestation (P=0.147).

Conclusion

Our results suggest that the number of significant correlations of fetal facial expressions in FGR fetuses increases more compared with that in AGA fetuses at 32–35 weeks of gestation. Due to the acceleration of neurological maturation and development in FGR fetuses, the control of facial expressions by the brain may be more evident compared with AGA fetuses at 32–35 weeks of gestation. However, the data and their interpretation in the present study should be taken with some degree of caution because of the small number of subjects studied. Further studies involving a larger sample size are needed to obtain strong or additional evidence.
The impact of lattice vibrations on the macroscopic breathing behavior of MIL-53(Al)
Authors: Hoffman Alexander E.J. , Wieme Jelle , Rogge Sven M.J. , Vanduyfhuys Louis , Van Speybroeck Veronique
Published: February 2019

The mechanism inducing the breathing in flexible metal-organic frameworks, such as MIL-53(Al), is still not fully understood. Herein, the influence of lattice vibrations on the breathing transition in MIL-53(Al) is investigated to gain insight in this phenomenon. Through solid-state density-functional theory calculations, the volume-dependent IR spectrum is computed together with the volume-frequency relations of all vibrational modes. Furthermore, important thermodynamic properties such as the Helmholtz free energy, the specific heat capacity, the bulk modulus, and the volumetric thermal expansion coefficient are derived via these volume-frequency relations using the quasi-harmonic approximation. The simulations expose a general volume-dependency of the vibrations with wavenumbers above 300 cm−1 due to their localized nature. In contrast, a diverse set of volume-frequency relations are observed for vibrations in the terahertz region (<300 cm−1) containing the vibrations exhibiting collective behavior. Some terahertz vibrations display large frequency differences over the computed volume range, induced by either repulsion or strain effects, potentially triggering the phase transformation. Finally, the impact of the lattice vibrations on the thermodynamic properties is investigated. This reveals that the closed pore to large pore phase transformation in MIL-53(Al) is mainly facilitated by terahertz vibrations inducing rotations of the organic linker, while the large pore to closed pore phase transformation relies on two framework-specific soft modes.