bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge Toward Cervical Cancer and Its Determinants Among Women Aged 30-49 in Jimma Town, Southwest Ethiopia
Authors: Nigussie Tadesse , Asefa Adane , Nigusse Aderajew , Admassu Bitiya
Published: December 2020

Background:

Cervical cancer is one of the common causes of premature death and disability in women worldwide. It is preventable through vaccination, and screening for precancerous lesions and early treatment. However, screening service uptake and treatment for cervical cancer face significant challenges in low-income countries due to poor information systems. The aim of this study was to assess knowledge of cervical cancer and its determinants among women aged 30-49 years living in Jimma Town, Southwest Ethiopia.

Methods:

A community-based cross-sectional study was undertaken from March 20 to April 15, 2017. The data were collected using a structured interviewer-administered questionnaire and analyzed by SPSS version 21. Multivariable logistic regression anaysis was done and variables with a p-value < 0.05 were considered statistically significant.

Results:

Of the interviewed women, only 321(43.6%) had adequate knowledge about cervical cancer and screening. Attending secondary school or above (AOR = 2.42, 95% CI: 1.24-4.74), using modern contraceptives (AOR = 6.31, 95% CI: 2.86-13.89), knowing somebody with cervical cancer (AOR = 2.24, 95% CI: 1.35-3.71) and knowing someone screened for cervical cancer (AOR = 2.23, 95% CI: 1.30-3.80) were associated with knowledge of cervical cancer.

Conclusion:

Knowledge of cervical cancer is low in the current study area even if appropriate knowledge regarding the disease is important in decreasing the incidence and prevalence of cervical cancer through screening and human pappiloma virus vaccination. Increasing awereness regarding the disease and prevention strategies are the key issue.
The Perfect Storm: Hidden Risk of Child Maltreatment During the Covid-19 Pandemic
Authors: Rodriguez Christina M. , Lee Shawna J. , Ward Kaitlin P. , Pu Doris F.
Published: December 2020

The Covid-19 pandemic upended the country, with enormous economic and social shifts. Given the increased contact from families living in virtual confinement coupled with massive economic disarray, the Covid-19 pandemic may have created the ideal conditions to witness a rise in children’s experience of abuse and neglect. Yet such a rise will be difficult to calculate given the drop in official mechanisms to track its incidence. The current investigation utilized two studies conducted early in the pandemic to evaluate maltreatment risk. In the first cross-sectional study, parents ( n = 405) reported increased physical and verbal conflict and neglect which were associated with their perceived stress and loneliness. In the second study, parents ( n = 106) enrolled in a longitudinal study reported increased parent-child conflict, which was associated with concurrent child abuse risk, with several links to employment loss, food insecurity, and loneliness; findings also demonstrated increases in abuse risk and psychological aggression relative to pre-pandemic levels. Findings are discussed in the context of a reactive welfare system rather than a pro-active public-health oriented approach to child maltreatment, connecting with families through multiple avenues. Innovative approaches will be needed to reach children faced with maltreatment to gauge its scope and impact in the pandemic’s aftermath.
Acute cytokine release syndrome after a first dose of pembrolizumab as second-line treatment for metastatic, programmed death-ligand 1-positive, non-small-cell lung cancer
Authors: Normand Clément V , Zender Hervé O , Staehli Dominique M , Chouiter-Djebaili Amina Faiza , John Gregor
Published: December 2020

Introduction

The use of programmed death-ligand 1 (PD-L1) checkpoint inhibitor therapy is expanding, although its adverse effects are not completely known. We report on a rare case of acute cytokine release syndrome related to pembrolizumab use in a patient with lung cancer.

Case report

A 79-year-old man with metastatic, PD-L1-positive, non-small-cell lung cancer developed a febrile condition associated with a systemic inflammatory response syndrome and suffered haemodynamic compromise four hours after the first intravenous administration of pembrolizumab. A thorough medical workup found no alternative cause and a grade 2 cytokine release syndrome (CRS) was diagnosed. Management and outcome: Aggressive fluid resuscitation and supportive therapy led to restitutio ad integrum.

Discussion

Acute CRS after the administration of a PD-L1 inhibitor is infrequent but could be a fatal condition. Supportive treatment and, if necessary, corticosteroids should be considered.
OCTA-guided navigated laser therapy for advanced macula neovascularization secondary to age related macular degeneration
Authors: Amoroso Francesca , Souied Eric H , Cohen Salomon Yves , Pedinielli Alexandre , Astroz Polina , Blanco Garavito Rocio , Capuano Vittorio , Querques Giuseppe , Miere Alexandra
Published: December 2020

Introduction:

To evaluate the effects of the Navilas system guided by optical coherence tomography angiography for advanced macular neovascularization (MNV) secondary to age-related macular degeneration (AMD).

Methods:

Prospective case-series including nine eyes presenting with advanced MNV with persistence of exudative signs, no longer responding to anti-VEGF therapy, best-corrected visual acuity at least of 1.3 logMar. All patients were treated with Navilas guided by overlaid optical coherence tomography angiography (OCTA) images at the site of branching large neovascular trunks.

Results:

Occlusion of large neovascular trunks successfully occurred in all nine included patients. OCTA analysis revealed, at 1 month follow up, MNV total area decreasing from 6.2 ± 3.1 to 2.6 ± 3.4 mm2. At 6 months follow up, mean MNV area was 3.3 ± 3.4 mm2 ( p = 0.008).

Conclusion:

This preliminary study showed that Navilas treatment guided by OCTA may represent an attractive therapeutic option in advanced neovascular lesions secondary to AMD.
A case of bilateral unusual retinal hemorrhages in a COVID-19 patient
Authors: Monferrer-Adsuara Clara , Castro-Navarro Verónica , González-Girón Nuria , Remolí-Sargues Lidia , Ortiz-Salvador Miguel , Montero-Hernández Javier , Cervera-Taulet Enrique
Published: December 2020

Purpose:

There have been anecdotal reports of ocular manifestations in the Coronavirus Disease 2019 (COVID-19). As the pandemic is spreading and the whole picture is yet unknown, ophthalmologists should be aware of unusual ocular presentations of COVID-19 since they could precede the development of severe respiratory distress.

Methods:

We report here the first case of a patient with bilateral unusual dot-blot retinal hemorrhages and retinal venous dilation who presented shortly thereafter a PCR-proven COVID-19.

Case report:

A 59-year-old woman presented with a 7 days history of blurred vision in both eyes. Fundus examination revealed bilateral venous stasis and dot and blot intra-retinal hemorrhages preceding the diagnosis of COVID-19 in a patient with mild respiratory symptoms that progressed within a few days to a severe respiratory distress. After 1 month of the COVID-19 treatment, fundus examination improved and fluorescein angiography demonstrated no diabetic retinopathy signs, no retinal vasculitis and no significant delay in arterial or venous filling.

Conclusion:

Intraretinal hemorrhages similar to those found in the retinopathy associated to blood dyscrasias could be an association with SARS-CoV-2 in the context of a coagulopathy induced by the infection.
Convulsive Status Epilepticus in a Child With Controlled Epilepsy and Concurrent COVID-19 Infection: A Case Report and a Quick Review
Authors: Khair Abdulhafeez M , Husain Sumair , Kaur Gurcharanjeet , Falchek Stephen
Published: December 2020

The current unprecedented COVID-19 pandemic has been another step toward learning about the unique interaction between viral infections and human nervous system. Very few scientific papers explored neuroinvasive and neurotropic potentials of the SARS-CoV-2 virus in children. We report a child with convulsive status epilepticus and confirmed COVID-19 infection. Brief review of current available literature was discussed.
The limits of literature as liberation: Colonialism, governmentality, and the humanist subject
Authors: Greedharry M
Published: December 2020

Scholars in both the humanities and management remain attached to the idea that literature will set us free. Whether this is because literary text seems unconstrained by our epistemes or reading literature offers a practice through which we will be able to shape ourselves into the people we want to be, many of us understand literature as something that offers us a chance to emancipate ourselves from the regime of knowledge we have now. Nevertheless, as the history of literature as colonial governmentality suggests, literature and literary study have been crucial forms of knowledge-power for creating and maintaining organizational structures as well as producing the willing subjects that make those structures work. This being so, how is it that are we still interested in using literature to make “better” people, whether the people in question are ”better” managers or their subordinates, rather than reorganizing literary study in the contemporary university?
Acoustic characterization of combustion chambers in reciprocating engines: An application for low knocking cycles recognition
Authors: Novella Ricardo , Pla Benjamín , Bares Pau , Jiménez Irina
Published: December 2020

In this paper the acoustic response of a combustion chamber is studied by assuming different pressure field excitation. The viscous effects on the combustion chamber and the finite impedance of the walls have been modeled with a first order system, which damps the resonance oscillation created by combustion. The characterization of the acoustic response of the combustion chamber has been used to identify the source of the excitation in order to distinguish normal combustion from knock. Two engines, a conventional spark ignited (SI) and a turbulent jet ignition (TJI) engine, were used, fueled with gasoline and compressed natural gas (CNG), respectively. The pressure fluctuations in the combustion chambers are analyzed and a pattern recognition system identifies the most likely source of excitation. This new criteria for knock identification permits a more consistent differentiation between knocking and no-knocking cycles, independent on the amplitude of the phenomenon, thus allowing the improvement for knock control algorithms, specially with combustion modes which heavily excite resonance, such as turbulent jet ignition or homogeneous charge compression ignition (HCCI).
Counterterrorism and the challenges of terrorism from the far right
Authors: Roach Kent
Published: December 2020

This article examines how post-9/11 counterterrorism has often not been applied to far-right terrorism. Discriminatory double standards in counterterrorism should not be tolerated. Nevertheless, the answer is not simply to ratchet up counterterrorism to apply to the far-right. The legitimate desire for symbolic equality should not blind us to the underlying weaknesses of many of those instruments both in preventing terrorism and in respecting rights. In some cases, such as the United Nation’s regime of individual sanctions related to financing and travel of those associated with al Qaeda and Daesh, application to the far-right is not legally possible. It will be suggested in this article that far-right terrorism should be used as an opportunity to re-evaluate the effectiveness and propriety of all counterterrorism. A preliminary assessment suggests that counterterrorism tied to international or national proscription may not be effective (both generally and specifically in relation to the far-right). More difficult cases involve whether terrorism offences and offences targeting speech should be applied against all forms of terrorism. Interventions regulating items and material on the Internet used by terrorists and programs to counter violent extremism and to rehabilitate offenders may be promising in addressing both far-right and Daesh-inspired terrorism. Both New Zealand’s increased regulation of guns and the Christchurch calls for greater regulation of the Internet follow these more promising strategies.
International Mindedness: A Revised Conceptual Framework
Authors: Metli Akın , Lane Jennie F.
Published: December 2020

This paper suggests a revised framework for explaining, developing and assessing international mindedness (IM). A review of the literature – that presents initiatives, challenges, and debates regarding IM – concludes with an overview of selected conceptual frameworks that have been used to develop a shared understanding of IM. When the authors applied one of these frameworks in a previous empirical study, they found during data analysis that some aspects of the framework’s key pillars played a more supportive role and that other components of IM needed further identification. As a result, this paper proposes a revision of the framework that features intercultural competence and global engagement, and identifies more specific components of these attributes, namely knowledge, skills, dispositions, and agency. The paper includes another review of the literature to emphasise how these components are important for the development, implementation, and assessment of international mindedness.
Factors Influencing Saudi Parents’ Choice of International Schools in Saudi Arabia
Authors: Alfaraidy Hamdah Abdullah
Published: December 2020

The Saudi Ministry of Education has recently begun to allow all Saudi families to enroll their children in international schools. The international curriculum offered by such schools represents a notably different choice compared with Saudi traditional public and private schools, both of which teach the same state-mandated curriculum. As a result of the change, there has been a surge in demand for international education; the number of schools has increased rapidly, and there has been a steady “student leak” towards them and away from traditional schools. Little is known about why Saudi parents choose to enroll their children in international schools. We explored this question by surveying 431 Saudi parents of children attending such schools to identify the main factors contributing to their choice. Although all factors examined were important to parents, curriculum and overall school quality emerged as the most important; socioeconomic status was not influential in their decisions.
Exploring enduring employment discrimination in favour of British and American teachers in ‘traditional international schools’
Authors: Bunnell Tristan , Atkinson Cherry
Published: December 2020

Volume 2 of this journal included an article (Canterford, 2003) which discussed ‘segmented labour markets’ in ‘international schools’. Using an economics lens, that paper investigated the predominance of British and American educators, concluding that a form of discrimination existed which was driven by demand-side factors. In particular, Canterford identified a labour market dominated by British and American actors, asserting that ‘requirements discriminate very effectively against teachers from certain areas of the world.’ Our paper re-visits and advances Canterford’s discussion, and argues that not only does there still seem to be a reliance on native English-speaking Anglo-American actors in what might be described as ‘traditional international schools’, but there is a further need to move beyond economic theory towards the application of a sociological one. By applying Pierre Bourdieu’s Social Field Theory we show how positive discrimination in favour of native English-speakers from certain Western/Global North nations can occur within a discrete level of activity, creating a condition that is evident yet most often misrecognised. A complex set of doxa endures within the arena, beginning at recruitment level and continuing within curriculum-delivery and teacher-retainment levels. We show how the field in general possesses a normative belief-system that promotes division within the labour market, yet at the same time makes it seem natural, legitimate, and ‘legal’. This situation, the nomos, is a powerful, structural condition that helps make positive discrimination in favour of British and American actors seem so fundamentally normal as to remain, for the most part, unremarked. The topic still requires substantially more investigation and validation. However, by theorising it, and thus better confronting it, we can arguably begin to deal with it.
Outlaw motorcycle gangs and their members’ crime: Examining the social organization of crime and its relationship to formal club hierarchy
Authors: van Deuren Sjoukje , Kleemans Edward , Blokland Arjan
Published: December 2020

In recent years, many European countries have taken far-reaching measures to combat the criminal activities of outlaw motorcycle gangs (OMCGs). Meanwhile, empirical research into the ways OMCGs are involved in and influence the crimes of their members is largely lacking. This study presents the main findings of research based on police files of cases that were filed against members of Dutch OMCGs. We apply a criminological scenario approach to analyse to what extent and in which ways OMCGs are involved in the crimes of their members. The results show that OMCG membership particularly plays an indirect role in the criminal behaviour of OMCG members. Board members, for example, give permission for criminal acts, regulate mutual relationships between members, non-members and rival OMCGs during conflict situations, and forbid (criminal) behaviour of members that is harmful to the OMCG. OMCGs function as a pool of co-offenders and as a market for criminal enterprises. Members also use the violent reputation of OMCGs in specific criminal activities. OMCGs are less frequently directly involved in crimes. Direct involvement of OMCGs is most apparent in organized inter-gang violence and violence against their own members.
Ventricular Assist Device Technology and Black-White Disparities on the Heart Transplant Wait List
Authors: Frech Adrianne , Tarrence Jake , Natale Ginny , Tumin Dmitry
Published: December 2020

Introduction:

Heart transplantation is the definitive treatment for end-stage heart failure. Left ventricular assist devices (LVADs) are a continually improving technology that extends life for some candidates on the heart transplant waiting list. Research Questions: Our objective is to compare Black-White differences in LVAD implantation and heart transplant outcomes during a period of technological innovation when the pulsatile flow LVAD was largely replaced by the continuous flow LVAD between 1999-2014.

Design:

We used transplant registry data from the United Network for Organ Sharing (N = 5,550) to identify Black and White patients with heart failure who used an LVAD as a bridge-to-transplant (BTT). Using logistic regression, we compared Black-White differences in access to newer LVAD technology and timing of implantation relative to wait listing for heart transplantation. We used competing-risks event history models to predict transplant outcomes across race, LVAD type, and timing of LVAD implantation.

Results:

Black and White candidates were equally likely to receive newer continuous flow LVADs, but Black candidates received LVADs later in the disease course (i.e. after transplant listing). This later timing of technological intervention contributed to poorer wait list outcomes among black transplant candidates, including lower likelihood of receiving a heart transplant and greater likelihood of being removed from the wait list due to worsening health.

Discussion:

Delayed LVAD implantation is more common among Black patients and is associated with poorer transplant outcomes.
Analysis of Linguistically and Culturally Tailored Initiatives in Websites of Kidney Transplant Programs in the United States Between 2013-2018
Authors: Caicedo Juan Carlos , Carbunaru Samuel , Brooks Joseph Tyler , Ortiz Christopher Chiodo , Ortiz Alejandro Chiodo , Benavides Xiomara , Niño Laura , Ortiz Jorge , Locke Jayme E.
Published: December 2020

Introduction:

Minority patients constitute the majority of the kidney transplant waiting list, yet they suffer greater difficulties in listing and longer wait times to transplantation. There is a lack of information regarding targeted efforts by transplant centers to improve transplant care for minority populations.

Research Question:

Our aim was to analyze all kidney transplant websites in the United States to identify changes over a 5-year period in the number of multilingual websites, reported culturally targeted initiatives, and center and provider diversity.

Design:

Surveys were developed to analyze center websites of all transplant programs in the United States. Those with incomplete information about their nephrology or surgical teams were excluded, resulting in 174 (73%) sites in 2013 and 185 (76%) in 2018. Results: Few websites were available in a language other than English, 6.3% in 2013 and 9.7% in 2018 (P = 0.24). Only 3 websites (1.3%) in 2013 and 7 (3.7%) in 2018 reported any evidence of a culturally targeted initiative (P = 0.23). In 2018, 35% of centers employed a Hispanic transplant physician, 77% had a transplant physician who spoke a language other than English, and 39% had a transplant physician who spoke Spanish.

Discussion:

Although minority patients are expected to grow in the United States, decreased access to transplantation continues to vex the transplant community. Very little progress has been made in the development of multilingual websites and culturally targeted initiatives.
Factors Influencing Emergency Department Utilization and Hospital Re-Admissions in a Predominantly Obese, Racially Diverse Urban Renal Transplant Population
Authors: Lichvar Alicia B. , Patel Alisha , Pierce Dana , Gimbar Renee Petzel , Tzvetanov Ivo , Benedetti Enrico , Campara Maya
Published: December 2020

Introduction:

Early emergency department and hospital re-admissions are common in renal transplant recipients, but data are lacking in unique populations. Study Aim: The purpose of this study was to identify patient risk factors for multiple acute care utilization events within the first year of renal transplantation.

Design:

This was a single-center, retrospective cohort study of adult renal transplant recipients between 9/2013-9/2016. Patients were compared across number of emergency department visits and by hospital re-admissions. Diagnoses were categorized. Univariate and multivariate logistic regression was used to assess risk for multiple acute care utilization events within the first 12 months post-transplant.

Results:

A total of 216 patients were analyzed and were on average 50.5 (SD 13.9) years old, redominantly Black (49.77%) with an average body mass index of 33.33 (9.8) and were recipients of deceased donor renal transplants (61.11%). A total of 105 (48.6%) patients visited the emergency epartment and 119 (55.1%) patients had a hospital readmission. Patients having a body mass index >35 kg/m2 did not differ across emergency department visit or hospitalization groups. Delayed graft function (OR 2.86, 95% CI 1.07-7.65) and previous renal transplant (OR 2.77, 95% CI 1.04-7.39) were significantly associated with multiple acute care utilizations.

Discussion:

Acute care utilization following renal transplantation was similar to previously reported experiences. Obesity did not impact use of acute care resources or patient outcomes. Strategies addressing potential preventable emergency visits and hospital re-dmissions should be promoted.
Assessment and Treatment of Selective Mutism in a Child With Autism Spectrum Disorder
Authors: Cengher Mirela , Clayborne Joy C. , Crouch Adrianna E. , O’Connor Julia T.
Published: December 2020

Over 60% of children diagnosed with selective mutism are also diagnosed with Autism Spectrum Disorder. Previous research established that behavioral interventions are effective at increasing speech in children with both diagnoses. However, few studies conducted assessments to determine environmental variables that inhibit speech, and such assessments are necessary for the development of effective and efficient treatments. This case study describes an assessment that evaluated the function(s) of selective mutism. The results confirmed that the participant did not talk to avoid social interaction and that mutism occurred primarily in the presence of multiple, unfamiliar people. Our first treatment focused on increasing tolerance for social interaction, demonstrated by an increase in speech production in the presence of unfamiliar people. Our second treatment focused on increasing qualitative aspects of the participant’s speech (i.e., both responses and initiations). Finally, we taught the participant’s parents to implement the treatment in naturalistic settings, and the participant demonstrated generalization of treatment effects across people and settings. Implications for clinical practice and future research are discussed.
Popliteal Venous Aneurysm With Pulmonary Embolism: A Case Report
Authors: Li Xiang , Wu Huaping , Zhang Li , Song Huanhuan , Zeng Cunliang
Published: December 2020

Popliteal venous aneurysm (PVA) is defined as an increase in the diameter of the popliteal vein, twice its normal dimension. Herein, we report a case of right PVA with severe pulmonary embolism in a 75-year-old woman who presented with sudden chest tightness and dyspnea. Clinical examination revealed hypotension and hypoxemia. Radiographic investigations revealed extensive pulmonary embolism and right fusiform PVA. Following thrombolysis, her blood pressure and oxygen saturation normalized. However, she developed right calf swelling, and angiography revealed a thrombus in the right PVA, which was managed by catheter-directed thrombolysis. Thereafter, a vascular bypass was performed using the left great saphenous vein as a conduit to treat recurrent thrombosis. Subsequent venography indicated a patent vein graft, acceptable blood flow velocity, no thrombosis residue, and no significant thrombosis. Follow-ups at 3, 6, and 12 months revealed satisfactory outcomes. In conclusion, if the systemic condition is conducive, a surgical resection and reconstruction of the popliteal vein is recommended for the treatment of PVAs.
Identifiable Patterns of Trait, State, and Experience in Chronic Stroke Recovery
Authors: Duncan E. Susan , Shereen A. Duke , Gentimis Thanos , Small Steven L.
Published: December 2020

Background

Considerable evidence indicates that the functional connectome of the healthy human brain is highly stable, analogous to a fingerprint.

Objective

We investigated the stability of functional connectivity across tasks and sessions in a cohort of individuals with chronic stroke using a supervised machine learning approach.

Methods

Twelve individuals with chronic stroke underwent functional magnetic resonance imaging (fMRI) seven times over 18 weeks. The middle 6 weeks consisted of intensive aphasia therapy. We collected fMRI data during rest and performance of 2 tasks. We calculated functional connectivity metrics for each imaging run, then applied a support vector machine to classify data on the basis of participant, task, and time point (pre- or posttherapy). Permutation testing established statistical significance.

Results

Whole brain functional connectivity matrices could be classified at levels significantly greater than chance on the basis of participant (87.1% accuracy; P < .0001), task (68.1% accuracy; P = .002), and time point (72.1% accuracy; P = .015). All significant effects were reproduced using only the contralesional right hemisphere; the left hemisphere revealed significant effects for participant and task, but not time point. Resting state data could also be used to classify task-based data according to subject (66.0%; P < .0001). While the strongest posttherapy changes occurred among regions outside putative language networks, connections with traditional language-associated regions were significantly more positively correlated with behavioral outcome measures, and other regions had more negative correlations and intrahemispheric connections.

Conclusions

Findings suggest the profound importance of considering interindividual variability when interpreting mechanisms of recovery in studies of functional connectivity in stroke.
Exploring the Bounds of Pygmalion Effects: Congruence of Implicit Followership Theories Drives and Binds Leader Performance Expectations and Follower Work Engagement
Authors: Veestraeten Marlies , Johnson Stefanie K. , Leroy Hannes , Sy Thomas , Sels Luc
Published: December 2020

The topic of work engagement is moving up on the managerial agenda as it sets the stage for numerous beneficial outcomes for both organizations and their employees. It is clear, however, that not all employees are equally engaged in their job. The current study taps into theory on positive self-fulfilling prophecies induced by leaders’ high expectations of followers (i.e., the Pygmalion effect) and examines their potential to facilitate follower work engagement. By integrating literature on implicit followership theories with the Pygmalion model, we investigate the assumption that leaders’ high expectations are universally perceived as and therefore foster the same desirable results for all employees. We argue and find that the extent to which followers’ work engagement benefits from high leader expectations depends on their implicit followership theory of industry (IFTI; i.e., the general belief that employees are hardworking, productive, and willing to go above and beyond). We also find that when followers hold a high IFTI but feel that their leader does not convey high expectations, their engagement at work suffers. In addition, we examine whether leaders’ IFTI forms the origin of naturally occurring Pygmalion effects. Our results show that a positive IFTI among leaders is especially interpreted as high/positive expectations by followers who also hold a high/positive IFTI. Our study introduces boundary conditions to the Pygmalion-at-work model by revealing the interactive role of leaders’ and followers’ implicit followership theory of industry. We contribute to the advancement of cognitive, follower-centric perspectives on leadership and provide evidence for the importance of schema congruence.
Retaining Opportunities, Completing Key Projects with Remote Student Employees During COVID-19
Authors: Handley Henry , Harris Kayla
Published: December 2020

As the field of higher education began furloughs and layoffs to alleviate COVID-19 budget concerns, cultural heritage workers were directed to clearly demonstrate how their work contributes to institutions’ educational missions. Although physical library and archival collections were deemed inaccessible and less critical during the pandemic than ebooks, electronic journals, and digitized special collections, the two special collections projects considered in this case study demonstrate the value of continuing collections management work remotely and the relevance of student employees and other contingent workers in libraries and archives. The projects—one an inventory and bibliography of books acquired from a defunct religious library, and the other a review of digitized audio cassette tapes with little content information outside of the audio itself—enabled the retention of student workers facing few summer job opportunities and ineligibility for unemployment insurance, providing additional experience as well as compensation during an economic, as well as public health, crisis.
Educational Change by Design: Creating a School of the Future
Authors: Wyatt Lisa G. , Scragg Benjamin S. , Stein Jennifer Y. G. , Mishra Punya
Published: December 2020

This case study, framed within a school–university partnership, highlights the tensions inherent to employing design-based approaches for educational change. The case illustrates core tensions between an abductive, open-ended, design-based approach to change versus more traditional (deductive/inductive) approaches to managing change in schools. The design process serves as a way to break away from the traditional “grammar of schooling” (Tyack & Tobin) in a system unaccustomed to radical change. The case highlights the challenges of maintaining fidelity to the design process within a range of logistical and resources constraints, such as the time available to participants to engage in the process, and the difficulty of rapidly prototyping a new school model within an existing educational ecosystem. In the teaching notes, we recommend a theoretical lens and set of questions for educational leaders to reflect on as they consider approaches to educational change in their own settings.
Exploring the Impact of Home-Schooling on the Psychological Wellbeing of Irish Families During the Novel Coronavirus (COVID-19) Pandemic: A Qualitative Study Protocol
Authors: O’Sullivan Katriona , McGrane Amy , Clark Serena , Marshall Kevin
Published: December 2020

Background:

The COVID-19 pandemic has placed severe restrictions on people’s behavior worldwide with school closures in many countries. These closures have shifted education from the classroom to the home. This change is unprecedented, and home-schooling has placed substantial stress on families across the world. As of 9 April 2020, 1.57 billion children were being educated by families that had little or no experience of protracted home-schooling. An essential but neglected issue related to COVID-19 is the psychological impact of home-schooling on family wellbeing, especially considering the other stressors they are experiencing including social isolation, fears of infection, frustration, boredom, inadequate information, and financial stress. This study explores the impact of home-schooling on family psychological wellbeing during COVID-19. These findings will help develop supports and interventions for this population.

Methods:

An exploratory qualitative study will be conducted using semi-structured interviews with a convenience sample of families (at least one parent and one child). Participants will be recruited using social media outlets, contacts of academic members and snowball sampling. Interviews will take place using Microsoft Teams and via telephone and recorded for transcription purposes. These transcripts will be analyzed using interpretative phenomenological analysis (IPA). Ethical approval has been granted by the Social Research Ethics Subcommittee (SRESC) Maynooth University (2407411). The Science Foundation Ireland (SFI) has funded the research with the COVID-19 rapid response grant. The dissemination of findings will be through open access journal publications, distribution of lay summaries, press release and policy papers.

Discussion:

The research findings will discuss the impact that home-schooling has had on family psychological wellbeing. It will examine how parents are managing their children’s education and learning while handling the other stresses associated with COVID-19. A deeper understanding of the impact of school closures and home-schooling on family processes is essential if the psychological wellbeing of families is to be protected and supported during challenging times such as health-related disasters.
Audiovisual speech recognition: A review and forecast
Authors: Xia Linlin , Chen Gang , Xu Xun , Cui Jiashuo , Gao Yiping
Published: December 2020

Audiovisual speech recognition is a favorable solution to multimodality human–computer interaction. For a long time, it has been very difficult to develop machines capable of generating or understanding even fragments of natural languages; the fused sight, smelling, touching, and so on provide machines with possible mediums to perceive and understand. This article presents a detailed review of recent advances in audiovisual speech recognition area. After explicitly representing audiovisual speech recognition development phase divided by timeline, we focus on typical audiovisual speech database descriptions in terms of single view and multi-view, since the public databases for general purpose should be the first concern for audiovisual speech recognition tasks. For the following challenges that are inseparably related to the feature extraction and dynamic audiovisual fusion, the principal usefulness of deep learning-based tools, such as deep fully convolutional neural network, bidirectional long short-term memory network, 3D convolutional neural network, and so on, lies in the fact that they are relatively simple solutions of such problems. As the principle analyses and comparisons related to computational load, accuracy, and applicability of well-developed audiovisual speech recognition frameworks have been conducted, we further illuminate our insights into the future audiovisual speech recognition architecture design. We argue that end-to-end audiovisual speech recognition model and deep learning-based feature extractors will guide multimodality human–computer interaction directly to a solution.
ATR and p-ATR are emerging prognostic biomarkers and DNA damage response targets in ovarian cancer
Authors: Feng Wenlong , Dean Dylan C. , Hornicek Francis J. , Wang Jinglu , Jia Yanyan , Duan Zhenfeng , Shi Huirong
Published: December 2020

Background:

Although ataxia-telangiectasia and Rad3 related (ATR) has an established role in the DNA damage response of various cancers, its clinical and prognostic significance in ovarian cancer remains largely unknown. The aims of this study were to assess the expression, function, and clinical prognostic relationship of ATR and phospho-ATR ser428 (p-ATR) in ovarian cancer.

Methods:

We confirmed ATR and p-ATR expression by immunohistochemistry (IHC) in a unique ovarian cancer tissue microarray constructed of paired primary, recurrent, and metastatic tumor tissues from 26 individual patients. ATR-specific small interfering RNA (siRNA) and ATR inhibitor VE-822 were applied to determine the effects of ATR inhibition on ovarian cancer cell proliferation, apoptosis, and DNA damage. ATR expression and the associated proteins of the ATR/Chk1 pathway in ovarian cancer cell lines were evaluated by Western blotting. The clonogenicity was also examined using clonogenic assays. A three dimensional (3D) cell culture model was performed to mimic the in vivo ovarian cancer environment to further validate the effects of ATR inhibition on ovarian cancer cells.

Results:

We show recurrent ovarian cancer tissues express higher levels of ATR and p-ATR than their patient-matched primary tumor counterparts. Additionally, higher expression of p-ATR correlates with decreased survival in ovarian cancer patients. Treatment of ovarian cancer cells with ATR specific siRNA or ATR inhibitor VE-822 led to significant apoptosis and inhibition of cellular proliferation, with reduced phosphorylation of Chk1 (p-Chk1), Cdc25c (p-Cdc25c), Cdc2 (p-Cdc2), and increased expression of cleaved PARP and γH2AX. Inhibition of ATR also suppressed clonogenicity and spheroid growth of ovarian cancer cells.

Conclusion:

Our results support the ATR and p-ATR pathway as a prognostic biomarker, and targeting the ATR machinery is an emerging therapeutic approach in the treatment of ovarian cancer.
Anthropometric Evaluation of Photographic Images Before and After Functional Nasal Surgery in Patients With Deviated Noses
Authors: Lindemann Joerg , Stupp Franziska , Scheithauer Marc , Schmadl Anna , Goldberg-Bockhorn Eva , Halbig Anna-Sophia , Hoffmann Thomas K. , Sommer Fabian
Published: December 2020

Background

Numerous techniques for correction of deviated noses have been described. Nevertheless, surgical management is challenging even for experienced rhinosurgeons. Often, a “residual deformity” after functional septorhinoplasty (SRP) due to a deviated pyramid syndrome may remain.

Objective

Therefore, the purpose of this study was to determine how frequent functional SRP in patients with a deviated nose results in “successful” straightening of the external nose based on standardized angle measurements. Possible influences having a positive or negative effect on the surgical success were identified.

Methods

Photo documentation of 607 patients with deviated noses (304 women, 303 men, median age 30 years) before and after nasal surgery were retrospectively analyzed using standardized angle measurements. The pre- and postoperative photos of the faces were anthropometrically measured. The median follow-up was 6 months.

Results

A “straight” deviated nose (I-type) was present in 225 patients (37%), a C-shaped nose (C-type) in 382 patients (63%). More than 75% of the patients presented a facial asymmetry. Based on angle measurements alone, a total of 452 (75%) noses were straightened or postoperatively improved. 155 noses (25%) still showed a biometric deviation. The I- or C-type had no relevant influence on outcome.

Conclusion

A purely biometric analysis of crooked noses is difficult and its importance is limited due to commonly pre-existing facial asymmetries. The risk of a “residual deviation” after rhinoplasty in patients with deviated noses must not be underestimated. This fact should be addressed as part of the informed consent. In particular, it should be mentioned that the surgical outcome can remain well below the patient’s aesthetic expectations. Not rarely, a revision surgery may be necessary.
A Geometrical Account to Explain the Fat-Face Illusion
Authors: Rawal Amit , Tseng Philip
Published: December 2020

Investigations of the “fat-face” illusion have unanimously agreed that the illusion is face-specific. Here, we offer several manipulations to highlight that the fat-face illusion is not restricted to the bottom image, isn’t a property of internal features, facial contour/texture, and in general isn’t even specific to faces. We propose the axis of horizontal asymmetry account to contextualize fat-face illusion as a geometry-led illusion.
Reasons for initiating long-acting antipsychotics in psychiatric practice: findings from the STAR Network Depot Study
Authors: Barbui Corrado , Bertolini Federico , Bartoli Francesco , Calandra Carmela , Callegari Camilla , Carrà Giuseppe , D’Agostino Armando , Lucii Claudio , Martinotti Giovanni , Mastromo Daniele , Moretti Daniele , Monzani Emiliano , Porcellana Matteo , Prestia Davide , Ostuzzi Giovanni ,   STAR Network Investigators
Published: December 2020

Background:

Long acting injectable (LAI) antipsychotics have been claimed to ensure treatment adherence and possibly reduce the daily burden of oral formulations. So far, only surveys investigating the theoretical prescribing attitudes of clinicians have been employed. On this basis, we aimed to investigate reasons for prescribing LAIs in a real-world, unselected sample of patients.

Methods:

The STAR Network Depot Study is an observational, multicentre study consecutively enrolling adults initiating a LAI over a 12-months period. Clinical severity was assessed with the Brief Psychiatric Rating Scale, and patient’s attitude toward medications with the Drug Attitude Inventory 10 items. Psychiatrists recorded reasons for LAI prescribing for each study participant. Responses were grouped into six non-mutually exclusive categories: aggressiveness, patient engagement, ease of drug taking, side-effects, stigma, adherence.

Results:

Of the 451 patients included, two-thirds suffered from chronic psychoses. Improving patient engagement with the outpatient psychiatric service was the most common reason for prescribing LAIs (almost 80% of participants), followed by increasing treatment adherence (57%), decreasing aggressiveness (54%), and improving ease of drug taking (52%). After adjusting for confounders, logistic regression analyses showed that reasons for LAI use were associated with LAI choice (e.g. first-generation LAIs for reducing aggressiveness).

Conclusion:

Despite the wide availability of novel LAI formulation and the emphasis on their wider use, our data suggest that the main reasons for LAI use have remained substantially unchanged over the years, focusing mostly on improving patient’s engagement. Further, clinicians follow implicit prescribing patterns when choosing LAIs, and this may generate hypotheses for future experimental studies.
Subspecialization in Family Medicine: Opinions, Preferences, and Practices of Family Physicians in Saudi Arabia
Authors: AlAteeq Mohammed A. , AlJoudi Abdullah S. , AlKhadli Yahia M.
Published: December 2020

Objective

In recent years, family medicine (FM) has shown many changes, including the development of sub-specialization. This study aimed to explore the opinions, preferences, and practices of Saudi family physicians with regard to sub-specialization within family practice.

Methods

This cross-sectional study was conducted from January to May 2018. Data were collected from 561 Saudi FM board-certified physicians and family medicine residents from all over SA via personal emails using a self-administered questionnaire consisting of questions aimed at examining participants’ opinions, preferences, and practices with regard to sub-specialization in family practice.

Results

Only 48 family doctors (20.2%) had the qualification of subspecialist. Diabetology was the most common clinical subspecialty. The majority of participants agreed with the statements in favor of sub-specialization in FM. About 73% approved of the idea of sub-specialization in FM, while 89% thought that sub-specialization would provide a source of expertise within the FM context. The most stated reasons to go for FM subspecialties were to earn more experience (65.1%), gain some sense of control of huge knowledge and skills of FM (53.7%), and earning extra money (47.8%).

Conclusions

This study revealed that majority of certified family physicians and FM residents in SA have positive attitude towards sub-specialization in FM and support the idea of sub-specialization to be practiced within the context of FM
Effects of Innovative and Traditional Teaching Methods on Technical College Students’ Achievement in Computer Craft Practices
Authors: Zhang Abei , Olelewe Chijioke Jonathan , Orji Chibueze Tobias , Ibezim Nnenna Ekpereke , Sunday Nnadi Hillary , Obichukwu Peter Uzochukwu , Okanazu Oliver Okechukwu
Published: December 2020

Recently, global trends in technological development have brought about innovations in educational paradigms, thus giving rise to significant adoption of learner-centered and problem-centered approaches with greater potential to impart the next generation of learners compared to a more dominant teacher-centered approach. In view of this, this study presents result of the effects of innovative pedagogy integration in computer craft practices among technical college students in Enugu State, Nigeria. Result shows that innovative pedagogies applied in teaching and learning of computer craft practices were more effective in enhancing learning outcomes than the conventional teaching method. Based on this, the study concludes that computing teachers should become more creative in their day-to-day teaching activities by adopting innovative teaching approaches that can make teaching and learning of computing studies more engaging to learners.