bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE NUMBERED HEAD TOGETHER (NHT) TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMK
Authors: Mardiana Mardiana
Published: October 2023

The instrument used in this research is a test of students' mathematical problem solving abilities which are tested. Before applied the model of learning in both classes pretest  in both classes can be seen the result is the average value of control class is 37.6 and the average grade of experimental 38,83. Then after given the treatment of learning model in both classes then given the posttest and got the result is the average value of control class is 58,6 and experiment class average value is 62,77. After the final test, both classes were given a questionnaire of learning responses and obtained a percentage of student responses of 66.53% for the experimental class and 59% for the control class. Based on the results of this study can be concluded tha  >  or 0.716> 0.381 so it can be said that there is the influence of cooperative learning model type Numbered Head Together (NHT) to the problem solving skills mathematical students class XI SMK Pelita Hamparan Perak. While the results of the research for questionnaire responses obtained students  <  or -3.125 <1.675 so it can be concluded that there is no difference in student learning response taught by cooperative learning model type Numbered Head Together (NHT) with conventional learning model.
PENGEMBANGAN MEDIA PEMBELAJARAN INTERAKTIF BERBASIS WEBSITE PADA MATERI BANGUN DATAR KELAS IV SD NEGERI 02 LIMA PULUH T.A. 2022/2023
Authors: Kurniawan Rizky , Tarigan Daitin , Simanjuntak Eva Betty , Mailani Elvi , Manurung Imelda Free Unita
Published: October 2023

This study aims to develop interactive learning media based on google sites on the material of flat building material in class IV SD Negeri 02 Lima Puluh. This type of research is Research and Development (R&D) research with the ADDIE development model which consists of Analysis, Design, Development, Implementation, and Evaluation. The Analysis stage carried out by researchers is analyzing needs, analyzing curriculum, analyzing media.Design stage is designing products and devices. The Development stage makes media and conducts validation. The Implementation stage conducts media trials to obtain practicality and potential effects. The Evaluation Stage is the researcher discussing the value of practicality and potential effects. For data collection techniques that researchers use are interviews, questionnaires, and learning outcomes tests. The results of learning media research developed using google sites are categorized as very feasible to use, with a percentage of 94.7% media experts and 90% material experts. The media is said to be very practical by obtaining a score of 96.6% of media practicality experts. The media is said to be very effective with a completeness value of 91.3%.
Analisis Model Pembelajaran Discovery Learning dalam Meningkatkan Kemampuan Menyelesaikan Soal Cerita Bangun Ruang Di Kelas V SD N 173435 Doloksanggul
Authors: Simamora Benyamin , Tarigan Daitin , Mailani Elvi , Rozi Fahrur , Prawijaya Septian
Published: October 2023

This research was conducted with the aim of knowing the analysis of the use of discovery learning models in improving the ability to solve cube and block word problems in class V SD N 173435 Doloksanggul. This research is a type of quantitative research with a descriptive approach. The population in this study were 1 homeroom teacher of class V and 19 students of class V SD N 173435 Doloksanggul. The sampling technique in this study was a probability sampling technique where each population has the same opportunity to be selected as a sample with certain considerations. The data collection technique used in this research is by using questionnaires, interviews, and documentation. The results of this study indicate that the use of the discovery learning model in improving the ability to solve cube and block word problems in class V SD N 173435 Doloksanggul is effective and well used in improving students' cube and block story problem solving with a percentage of 52.63%.
PENGEMBANGAN MEDIA VIDEO ANIMASI BERBASIS MACROMEDIA FLASH ORGAN GERAK HEWAN DAN MANUSIA KELAS V SDN 046579 KABUPATEN KARO
Authors: Tarigan Septian Pratama , Rozi Fahrur
Published: October 2023

This study aims to determine the level of feasibility, practicality, and effectiveness of macromedia flash-based animation video learning media for the movement of animals and humans for class V at SD 046579 Tanah Karo T.A 2022/2023. This type of research is R&D with the ADDIE development model with 5 research stages, namely analysis, design, implementation, evaluation. The subjects in this study were fifth grade students at SDN 046579 Tanah Karo. Data collection techniques in this study were teacher interviews, material and media validation questionnaires, educator practitioner (teacher) questionnaires and test questions. The results showed that the validator by the material expert got a score of 91 with a percentage of 91% in the "very decent" category and the results of the design validation by the media expert validator got a score of 90 with a percentage of 90% in the "very decent" category. The practicality test by educational practitioners obtained a score of 96 with a percentage of 96% in the "Very Practical" category. Based on the effectiveness test of Learning Media that results can be seen after using Learning Media with the Macromedia Flash application that was developed, student scores increased from the start before using learning media with the Macromedia Flash application students got an average score of 53.0 increasing to 87.5 after using the media. From these results it can be concluded that macromedia flash based animation video media is feasible, practical, and effective to use.
PENGEMBANGAN MEDIA DIORAMA TAMAN SATWA UNTUK MENINGKATKAN MINAT BELAJAR PESERTA DIDIK PADA MATA PELAJARAN IPA KELAS V MI
Authors: Nujum Tis'atun , Hamidah Allinda
Published: October 2023

This study aims to develop taman satwa diorama media to increase students' learning interest, determine the feasibility level of taman satwa diorama media, and determine the level of students’ learning interest in science subjects class V MI Thoriqotul Hidayah Bulutigo after using taman satwa diorama media in learning activities. This type of research is research and development (R&D) used the ADDIE development model. The sample in this study were fifth grade students, totaling 10 students. The data collection technique in this study were questionnaires and documentation. The analysis technique used is descriptive qualitative and quantitative analysis. The results of research and development of taman satwa diorama media showed that taman satwa diorama media were appropriate to be used as learning media in fifth grade students in science subjects to increase students' learning interest. This could be seen from the results of the validation test of media experts by 91%, material experts by 82%, language experts by 88%, practitioners (teachers) by 100%, and from the results of field trials by 97.4% which showed very valid criteria. Based on the results of the data analysis of students' learning interest questionnaires, there was a significant difference in the initial and final students' learning interest with the acquisition of an average score which was initially only 55% with the moderate category increasing to 93% with the very high category.  Thus it could be concluded that taman satwa diorama media can increase students' learning interest in science subjects of fifth grade students at MI Thoriqotul Hidayah Bulutigo for the 2022/2023 academic year.
INTERNALISASI NILAI-NILAI RELIGIUS DALAM MEMBENTUK AKHLAK SISWA SD KEMALA BHAYANGKARI 1 SURABAYA
Authors: Yuliah Yuliah , Marfiyanto Tri
Published: October 2023

This research discusses the religious values instilled in the teaching of Islamic Religious Education (PAI) to students at Kemala Bhayangkari 1 Elementary School in Surabaya, as well as the process of introducing religious values through Islamic education and the influencing factors at the school. A field study with a descriptive approach involved the school principal and teachers at Kemala Bhayangkari 1 Elementary School in Surabaya. Data was collected through observation, interviews, and documentation, then validated through comparing information from informants and observation results, followed by deductive analysis. Research findings: 1) Religious values in PAI instilled in students include piety, politeness, tolerance, harmony, empathy, discipline, care, and ethical conduct towards the environment. 2) The process of introducing religious values occurs through role models and habituation. 3) Supporting and inhibiting factors for internalizing religious values encompass the stages of response and assessment, but have not fully reached the stage of value characteristics. While some students have already practiced these values, they have not fully integrated into their character
Rebuilding Cities in a Digital age: The Destruction and Reconstruction of Heritage in Palmyra, Warsaw, and Amsterdam
Authors: Duindam David
Published: October 2023

This paper investigates recent digital reconstruction efforts of Syrian heritage sites. These projects illustrate a Western saviorism emblematic of the colonial roots of archaeology and heritage practices. Rather than offering a solution, digital innovation further exacerbates the unequal distribution of knowledge and power. In order to denaturalize narratives of technological progress, this paper compares the digitally produced replica of Palmyra’s Arch of Triumph, first presented in London in 2016, to the postwar reconstructions of Warsaw and the Hollandsche Schouwburg, a Holocaust site in Amsterdam. By comparing digital and nondigital memory technologies, we can examine how Western conceptions of heritage are entangled with the very possibilities of destruction and reconstruction.
The Willet-Holthuysen House as a Site of Resistance
Authors: Maat Dorine
Published: October 2023

This paper examines the Willet-Holthuysen House, a canal house museum in Amsterdam, in the context of World War II. Originally bequeathed to Amsterdam by its last owner, Louisa Willet-Holthuysen, in 1895, the house has a rich history of being home to various families and institutions. While some connections between the house and World War II have been previously established through oral sources, this essay introduces additional source material to shed further light on the house as a place of resistance. The research uncovers that the Willet-Holthuysen House served not only as a location within the Council of Resistance's network but also provided shelter for a person in hiding and accommodated a family actively involved in the resistance. This reveals that the house was more than just a place for art collection and opulence; it operated as a vital node in the resistance network, offering a hiding place and serving as a meeting spot for illegal resistance activities.
Architecture of Destruction and Healing
Authors: Mačkić Arna
Published: October 2023

On November 29, 2017 Slobodan Praljak, the architect of the destruction of Bosnia-Herzegovina in the 1990s, had committed suicide. Libraries, bridges, museums, universities, mosques and squares were purposefully destroyed by him. For these crimes – against buildings, public spaces and landscapes – he was not tried. In one of Praljak's 'main acts', he ordered the destruction of the Old Bridge in Mostar. The story of the Old Bridge is that of Mostar's multi-ethnicity. Many books, plays and films have been devoted to it. It was that very story that had to be destroyed. And that was precisely Praljak's expertise. Before becoming a general, Praljak was a creator and manager in the cultural field, like many of his fellow criminals. Slobodan Praljak’s actions show us that architecture can be used consciously and unconsciously to dislocate and destroy human relationships and the environment. I call this architectural disaster. Rebuilding is impossible if the disaster is reduced to an individual problem or responsibility, no lessons are learned from it, and the history of violence, exclusion and segregation keeps repeating itself. What are ways to reconnect and build these relationships? How can we work on recovery, so that victims get a perspective for the future?
The Polylogue
Authors: Shirzad Sahar , Demmers Jolle , Warsame Fatima , Keulemans Chris
Published: October 2023

A Roundtable on War, Conflict and the City, featuring Sahar Shirzad, Jolle Demmers, Chris Keulemans and Fatima Warsame. In this round table four expert participants discuss the effects of war and conflict on the city of Amsterdam, from their own perspectives and areas of expertise.
Dublin 1904: Conflict in ‘The Dead’
Authors: Mills Imogen
Published: October 2023

In recent years, there has been growing interest in the role of futurity and hope in memory studies. This paper contributes to this conversation by examining futurity in a city marked by colonial conflict in the context of “The Dead”, the final short story from Dubliners by James Joyce. Drawing on discursive analysis, I argue that the postcolonial writer can rewrite the city, ripe for a new and unknown future. To support this argument, I analyze layers of the colonized urban space. Specifically, I look at the Wellington monument and the statue of Daniel O’Connell. Through this analysis, I demonstrate that futurity is an ambiguous concept capable of holding all possible iterations of the future after conflict. This paper contributes to ongoing debates about surpassing the current focus within memory studies on traumatic memories by drawing on research on hope, as it is lifeaffirming and inherently futureoriented, by Ann Rigney, and David P. Rando. In addition, it challenges conventional readings of conflict and trauma by extending hope to the dead. Thus, it exhibits how death helps to conceptualize an unknown future.
A Momentary Lapse in Memory: An Inquiry into (Re)Memory and Trauma Embodiment
Authors: Milutinović Senka
Published: October 2023

This essay investigates the impact of the archival practice on oral histories of conflict. Specifically, it asks to what capacity can the lived experience be devoured by the grinding machine of forced institutional remembrance, and how can it defy such a predicament? The inquiry to this question was studied through the oral history of the author’s friends, family and neighbors concerning the 1999 NATO bombing of Yugoslavia. This military intervention was done in response to the oppressive regime of Slobodan Milošević and remains fresh in the Serbian collective memory. Utilizing qualitative generative interviews, a case study of the author’s parents’ approaches to archiving, and personal footage recorded by the RadioTelevision of Serbia, the paper examines differences between institutional and personal archival practices. The analysis displays that institutional remembrance can claim the lived experience through collective memory, which is reinstated by commemorative practices and archiving. In contrast, oral histories of conflict result in a different type of narrativebuilding and remembering. They are characterized by mechanisms such as collective editing, transmission, and non linearity, which resist standardization and instrumentalization. This paper advocates for reconsidering static preservation oriented modes of institutional archiving, proposing instead, to embrace nonreproductible aspects or the unreliable of oral history.
Pastiche of Threats: A Spatial Analysis of Military Urban Training Centres
Authors: Roei Noa , Schwake Gabriel
Published: October 2023

This paper focuses on two case studies of urban military training centres, representing different combat scenarios, and generating different imaginary spatial manifestations. Using maps, drawings, photographs, and 3D models, we analyse how the architectural and urban characteristics of both cases inform the manner in which Arab built space is simultaneously conceived and perceived as what we develop in this paper as a pastiche of threats, violence, and domination. Approaching the issue from a spatial perspective, we address the materials used in each space; how spaces were planned in relation to combat legacies, and how their planners ignored noncombatant usage of public space in their creation of civilian-like military infrastructure. At the same time, we wish to address the neverending “passion for the Real”, which cannot be satisfied by any simulacra. By doing so, we map out the way abstract imaginaries are manifested and materialized spatially, attending almost literally to the “architecture of vision” involved in contemporary practices of power.
Network Infrastructure Security: Challenges and Protection Strategies
Authors: Lara Guijarro Elva Gioconda
Published: October 2023

Network infrastructure is essential in today's society, connecting people, businesses and services around the world. However, its growing relevance has led to an increase in threats and cyber-attacks directed towards it. The main objective of this researchwas to analyze emerging threats to network infrastructure and determine optimal strategies for its protection. Using a qualitative methodology, documentary analysis and specialized literature 184review were used to collect data. The results revealed an increasing sophistication of cyber-attacks targeting network infrastructure, highlighting the need to implement proactive and adaptive security measures. Several protection strategies were also identified, including the use of artificial intelligence and machine learning to detect and mitigate threats in real time. In addition, it was found that ongoing training and awareness of network security professionals is critical to address current and future challenges.
Analisis Faktor-Faktor yang Mempengaruhi Nilai Perusahaan pada Perusahaan Manufaktur yang Terdaftar di BEI Periode 2013-2018
Authors: Miftakhul Jannah
Published: October 2023

The purpose of this research is to examine the factors that influence company value. The type of research used is quantitative research in explanatory format. The population in this research are manufacturing companies listed on the Indonesia Stock Exchange for the 2013-2018 period. The sampling technique was carried out using the purposive sampling method. The exogenous variables in this research are ownership structure which is proxied by managerial ownership and institutional ownership as well as investment opportunity set which is proxied by market value book equity (mvebve). Meanwhile, the endogenous variable in this research is company value which is proxied by Price Book Value. This research uses secondary data in the form of financial reports and statistical data for manufacturing companies for the 2013-2018 period. The data analysis technique used is multiple regression analysis with SPSS 21 software. The results of this research show that: (1) managerial ownership has no significant effect on company value; (2) institutional ownership has no significant effect on firm value; and (3) investment opportunity set has a significant effect on company value.
Analisa Kepuasan Pelayanan UMKM Jasa Internet dalam Perspektif Profil Konsumen (Studi Kasus : Konsumen JW Network Indonesia)
Authors: M. Dayat  , Mochamad Sirodjudin
Published: October 2023

This research aim to know: (1) Client profile of JWnet, (2) Customer’s level of fulfillment and (3) Customer’s differential fulfillment of JWnet, assessed by age, sex, occupation, and education level. This applied research using descriptive case of the client of JWnet, using 100 clients as samples. Literature study and questioner used to collect the information. And then data processing uses percentage analysis, One Way ANOVA and Consumer Satisfaction Index analysis. The results of the study show: (1) the profile of the respondents is dominated by men (63%), aged 21-25 years (38%), the majority have university education (66%) and work as students (44%); (2) based on customer satisfaction index is very satisfied (78%), dissatisfied (17%), and satisfied (5%); and (3) and there is a difference in the level of satisfaction, depends on gender, age, and profession, meanwhile there is a significant difference between the level of satisfaction of educated consumers for internet services from JWnet.
Turismo e hospitalidade gay friendly na perspectiva da comunidade LGBTQIA+
Authors: Silva Bernardo José Costa , Carvalho Karoliny Diniz
Published: October 2023

Neste artigo discutem-se as opiniões da comunidade LGBTQIA+ acerca do nível de acolhimento nos destinos turísticos brasileiros. Também é abordada a relação entre turismo e hospitalidade, as características do segmento LGBTQIA+ e o surgimento dos espaços gay friendly. Metodologicamente, a pesquisa caracterizou-se por ser exploratória e descritiva, utilizando-se a pesquisa bibliográfica e a pesquisa de opinião (survey). Aplicaram-se questionários on-line junto à comunidade LGBTQIA+ no período de 15 de abril a 15 de julho de 2021. Os resultados da pesquisa demonstraram que parcela significativa dos visitantes LGBTQIA+ já vivenciaram alguma situação de constrangimento e desconforto nos equipamentos turísticos e consideram que o setor de turismo do Brasil não está preparado para receber a comunidade de forma acolhedora e respeitosa. O estudo aponta para uma maior articulação entre os gestores públicos, privados e as demandas LGBTQIA+ com vistas a transformar os espaços urbanos em locais de intercâmbio, acolhimento e promoção da diversidade sexual.
Relação porto-cidade e a operacionalidade turística do terminal marítimo de passageiros de Natal – RN
Authors: Silva Júnior Francisco Xavier da , Nóbrega Wilker Ricardo de Mendonça
Published: October 2023

O objetivo desta pesquisa centra-se em compreender quais são os obstáculos operacionais do turismo encontrados no Terminal Marítimo de Passageiros do Porto de Natal que culminam na relação porto-cidade. Para fundamentar o debate, explorou-se sobre os diversos teóricos que pensam zonas portuárias e suas conexões com a cidade e o turismo. Os dados foram obtidos através do material midiático e das atas institucionais do porto. Para analisá-los, foi utilizado como técnica o ciclo de análise issue-attention cycle de Downs (1972) para averiguar os traços das barreiras operacionais do terminal, verificando de que forma a mídia atuou em todo o processo, do pré-problema ao pós-problema. Após a aplicação do ciclo no contexto da política pública do TMP, foi possível entender que a frágil relação porto-cidade dificultou a interconexão com o turismo e não oportunizou um novo olhar para o bairro histórico. Todavia, acredita-se que os interesses na operacionalidade do TMP para fins turísticos são parte para justificar a necessidade de melhores empreendimentos turísticos e parte para estimular os grupos de interesse que se aproximam uns dos outros pelos acúmulos de seus capitais econômicos, culturais e sociais.
Metodologias de ensino-aprendizagem em turismo: percepção de estudantes de curso superior
Authors: Claudino Adson De Lima , Araújo José Mateus Silva de , Cavalcante Islaine Cristiane Oliveira Gonçalves da Silva , Alexandre Mauro Lemuel De Oliveira
Published: October 2023

Metodologias de ensino possuem notoriedade no processo de ensino-aprendizagem na medida em que buscam otimizar as práticas pedagógicas, sendo assim, investigar a temática da educação em turismo pelo viés das metodologias de ensino revela-se como uma área pertinente de estudos. O objetivo deste artigo foi analisar a percepção de discentes do curso superior de turismo da Universidade Federal do Rio Grande do Norte (UFRN) sobre as metodologias de ensino aplicadas pelos docentes. A pesquisa se classifica como qualitativa e quantitativa, transversal, exploratória e descritiva. Os dados foram coletados por meio de um questionário on-line via Google Forms com alunos que tiveram a experiência de ensino presencial e remoto. Para a interpretação dos dados utilizou-se a análise de conteúdo, a análise de similitude através do software Iramuteq e estatística descritiva. Os resultados apontam que os discentes vislumbram o uso de metodologias de ensino como ferramentas relevantes para o ensino e para a aprendizagem, e que métodos com caráter prático possuem maior aderência por reverberar em melhores resultados, mostrando a necessidade de busca por métodos que otimizem a absorção do conhecimento e motive participação em sala de aula. Conclui-se que o ensino do turismo - presencial ou remoto - requer propostas didáticas, que possibilitem aos educandos desenvolver um olhar crítico-reflexivo sobre o setor, atributos potencializados por meio da utilização de metodologias ativas de ensino e sinergia entre professor e aluno em sala de aula.
Editorial
Authors: Zouain Deborah Moraes
Published: October 2023

Prezados/as leitores/as!Seguem breves comentários sobre os artigos que compõem a presente edição.Boa leitura!    Deborah Moraes ZouainDiretora e editora-chefe
Editorial V.17,N.2 (2023)
Authors: Zouain Deborah Moraes
Published: October 2023

Prezados/as leitores/as! Seguem breves comentários sobre os artigos que compõem a presente edição. Boa leitura!
Dynamic analysis and experiment of chaotic circuit of non-homogeneous fractional memristor with bias voltage source
Authors: Wu Chao-Jun , Fang Li-Yi , Yang Ning-Ning ,   Xi’an Key Laboratory of Interconnected Sensing and Intelligent Diagnosis for Electrical Equipment, School of Electronic Information, Xi’an Polytechnic University, Xi’an 710048, China,   School of Electrical Engineering, Xi’an University of Technology, Xi’an 710048, China
Published: October 2023

A physical memristor has an asymmetric tight hysteresis loop. In order to simulate the asymmetric tight hysteresis curve of the physical memristor more conveniently, a fractional-order diode bridge memristor model with a bias voltage source is proposed in this paper, which can continuously regulate the hysteresis loop. Firstly, based on fractional calculus theory, a fractional order model of a diode bridge memristor with a bias voltage source is established, and its electrical characteristics are analyzed. Secondly, by integrating it with the Jerk chaotic circuit, a non-homogeneous fractional order memristor chaotic circuit model with a bias voltage source is established, and the influence of bias voltage on its system dynamic behavior is studied. Once again, a fractional-order equivalent circuit model is built in PSpice and validated through circuit simulation. The experimental results are basically consistent with the numerical simulation results. Finally, the experiments on the circuit are completed in LabVIEW to validate the correctness and feasibility of the theoretical analysis. The results indicate that the fractional order memristor with bias voltage source can continuously obtain asymmetric tight hysteresis loop by adjusting the voltage of the bias voltage source. As the bias power supply voltage changes, the non-homogeneous fractional order memristor chaotic system exhibits that the period doubling bifurcation turns into chaos due to the symmetry breaking.
Transformation of valence signaling in a mouse striatopallidal circuit
Authors: Lee Donghyung , Lau Nathan , Liu Lillian , Root Cory M
Published: October 2023

The ways in which sensory stimuli acquire motivational valence through association with other stimuli is one of the simplest forms of learning. Although we have identified many brain nuclei that play various roles in reward processing, a significant gap remains in understanding how valence encoding transforms through the layers of sensory processing. To address this gap, we carried out a comparative investigation of the mouse anteromedial olfactory tubercle (OT), and the ventral pallidum (VP) - 2 connected nuclei of the basal ganglia which have both been implicated in reward processing. First, using anterograde and retrograde tracing, we show that both D1 and D2 neurons of the anteromedial OT project primarily to the VP and minimally elsewhere. Using two-photon calcium imaging, we then investigated how the identity of the odor and reward contingency of the odor are differently encoded by neurons in either structure during a classical conditioning paradigm. We find that VP neurons robustly encode reward contingency, but not identity, in low-dimensional space. In contrast, the OT neurons primarily encode odor identity in high-dimensional space. Although D1 OT neurons showed larger responses to rewarded odors than other odors, consistent with prior findings, we interpret this as identity encoding with enhanced contrast. Finally, using a novel conditioning paradigm that decouples reward contingency and licking vigor, we show that both features are encoded by non-overlapping VP neurons. These results provide a novel framework for the striatopallidal circuit in which a high-dimensional encoding of stimulus identity is collapsed onto a low-dimensional encoding of motivational valence.
Neurophysiological trajectories in Alzheimer’s disease progression
Authors: Kudo Kiwamu , Ranasinghe Kamalini G , Morise Hirofumi , Syed Faatimah , Sekihara Kensuke , Rankin Katherine P , Miller Bruce L , Kramer Joel H , Rabinovici Gil D , Vossel Keith , Kirsch Heidi E , Nagarajan Srikantan S
Published: October 2023

Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β and misfolded tau proteins causing synaptic dysfunction, and progressive neurodegeneration and cognitive decline. Altered neural oscillations have been consistently demonstrated in AD. However, the trajectories of abnormal neural oscillations in AD progression and their relationship to neurodegeneration and cognitive decline are unknown. Here, we deployed robust event-based sequencing models (EBMs) to investigate the trajectories of long-range and local neural synchrony across AD stages, estimated from resting-state magnetoencephalography. The increases in neural synchrony in the delta-theta band and the decreases in the alpha and beta bands showed progressive changes throughout the stages of the EBM. Decreases in alpha and beta band synchrony preceded both neurodegeneration and cognitive decline, indicating that frequency-specific neuronal synchrony abnormalities are early manifestations of AD pathophysiology. The long-range synchrony effects were greater than the local synchrony, indicating a greater sensitivity of connectivity metrics involving multiple regions of the brain. These results demonstrate the evolution of functional neuronal deficits along the sequence of AD progression.
PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification
Authors: Valer José Antonio , Deber Alexandre , Wits Marius , Pimenta-Lopes Carolina , Goumans Marie-José , Rosa José Luis , Sánchez-Duffhues Gonzalo , Ventura Francesc
Published: October 2023

Heterotopic ossification (HO) occurs following mechanical trauma and burns, or congenitally in patients suffering from fibrodysplasia ossificans progressiva (FOP). Recently, we demonstrated that inhibitors of phosphatidyl-inositol 3-kinase alpha (PI3Kα) may be a useful therapy for patients undergoing HO. In this study, using the already marketed BYL719/Alpelisib/Piqray drug, we have further confirmed these results, detailed the underlying mechanisms of action, and optimized the timing of the administration of BYL719. We found that BYL719 effectively prevents HO even when administered up to three to seven days after injury. We demonstrate in cell cultures and in a mouse model of HO that the major actions of BYL719 are on-target effects through the inhibition of PI3Kα, without directly affecting ACVR1 or FOP-inducing ACVR1
R206H
kinase activities.
In vivo
, we found that a lack of PI3Kα in progenitors at injury sites is sufficient to prevent HO. Moreover, time course assays in HO lesions demonstrate that BYL719 not only blocks osteochondroprogenitor specification, but also reduces the inflammatory response. BYL719 inhibits the migration, proliferation and expression of pro-inflammatory cytokines in monocytes and mast cells, suggesting that BYL719 hampers the hyper-inflammatory status of HO lesions. Altogether, these results highlight the potential of PI3Kα inhibition as a safe and effective therapeutic strategy for HO.
Performance analysis of aspect-level sentiment classification task based on different deep learning models
Authors: Cao Feifei , Huang Xiaomin
Published: October 2023

Aspect-level sentiment classification task (ASCT) is a natural language processing task that aims to correctly identify specific aspects and determine their sentiment polarity from a given target sentence. Deep learning models have been proven to be effective in aspect-based sentiment classification tasks, and the mainstream Aspect-level sentiment classification (ASC) models currently constructed generally assume that the training and test datasets are Gaussian distribution (e.g., the same language). Once the data distribution changes, the ASC model must be retrained on the new distribution data to achieve good performance. However, acquiring a large amount of labeled data again typically requires a lot of manpower and money, which seems unlikely, especially for the ASC task, as it requires aspect-level annotation. This article analyzes the performance of sequence-based models, graph-based convolutional neural networks, and pre-training language models on the aspect-level sentiment classification task using two sets of comment datasets in Chinese and English, from four perspectives: classification performance, performance with different aspect numbers, specific case performance, and computational cost. In this article, we design a state-of-the-art ASC-based classification method and conduct a systematic study on eight public standard English and Chinese datasets with various commonly used assessment measures that provide directions for cross-language migration. Finally, we discuss the limitations of the study as well as future research directions.
Assessing the effect of heavy metals on maize (Zea maysL.) growth and soil characteristics: plants-implications for phytoremediation
Authors: Atta Muhammad Imran , Zehra Syeda Sadaf , Ali Habib , Ali Basharat , Abbas Syed Naveed , Aimen Sara , Sarwar Sadia , Ahmad Ijaz , Hussain Mumtaz , Al-Ashkar Ibrahim , Elango Dinakaran , El Sabagh Ayman
Published: October 2023

Background

Heavy metal pollution has become a global environmental issue. Heavy metals are contaminating the agro-soils, growing crops, and vegetables through different agricultural practices. In this study, besides the phytoremediation potential of maize, the role of chromium (Cr) and lead (Pb) on crop and soil health has been investigated.

Methods

Two maize varieties, Pak-Afgoi and Neelem, were grown under varying concentrations of Cr (50–300 ppm) and Pb (30–300 ppm) and different growth parametersi.e., seed germination, leaf size/number, stem girth, plant height, biomass, chlorophyll content, relative growth rate (RGR), and net assimilation rate (NAR) were studied under Cr and Pb stress. Likewise, the effect of metals was also assessed on different soil characteristics including soil texture, pH, EC, soil organic matter, urease activity and nutrients.

Results

Studied plant attributes were adversely affected by heavy metals toxicity. Affected values of RGR and NAR showed a linear correlation with affected growth and dry matter yield of maize. Heavy metals impacted different soil parameters including soil microbial performance and revealed a declining trend as compared to control soil. Maize varieties showed a significant phytoremediation potentiali.e., uptake of Cr and Pb was 33% and 22% in Pak-Afgoi, while Neelem showed 38% and 24% at 300 ppm, respectively. Data regarding metal translocation factor (TF), bioaccumulation factor (ACF), and biomagnification ratio (BMR) significantly revealed the potential of maize varieties in the removal of Cr and Pb metals from affected soils. However, Cr-accumulation was higher in shoots, and Pb accumulated in plant roots showed a differential behavior of metal translocation and affinity with the varieties. These maize varieties may be recommended for general cultivation in the Cr and Pb-contaminated areas.
Identification of genetic loci for early maturity in spring bread wheat using the association analysis and gene dissection
Authors: Kiseleva Antonina A. , Leonova Irina N. , Ageeva Elena V. , Likhenko Ivan E. , Salina Elena A.
Published: October 2023

Background

Early maturity in spring bread wheat is highly desirable in the regions where it enables the plants to evade high temperatures and plant pathogens at the end of the growing season.

Methods

To reveal the genetic loci responsible for the maturity time association analysis was carried out based on phenotyping for an 11-year period and high-throughput SNP genotyping of a panel of the varieties contrasting for this trait. The expression of candidate genes was verified using qPCR. The association between the SNP markers and the trait was validated using the biparental F2:3 population.

Results

Our data showed that under long-day conditions, the period from seedling to maturity is mostly influenced by the time from heading to maturity, rather than the heading time. The QTLs associated with the trait were located on 2A, 3B, 4A, 5B, 7A and 7B chromosomes with the 7BL locus being the most significant and promising for its SNPs accelerated the maturity time by about 9 days. Gene dissection in this locus detected a number of candidates, the best being TraesCS7B02G391800 (bZIP9) and TraesCS7B02G412200 (photosystem II reaction center). The two genes are predominantly expressed in the flag leaf while flowering. The effect of the SNPs was verified in F2:3 population and confirmed the association of the 4A, 5B and 7BL loci with the maturity time.
The gray matter atrophy and related network changes occur in the higher cognitive region rather than the primary sensorimotor cortex after spinal cord injury
Authors: Chen Xin , Wang Ling , Zheng Weimin , Yang Yanhui , Yang Beining , Hu Yongsheng , Du Jubao , Li Xuejing , Lu Jie , Chen Nan
Published: October 2023

Objective

This study used functional magnetic resonance imaging (fMRI) to explore brain structural and related network changes in patients with spinal cord injury (SCI).

Methods

Thirty-one right-handed SCI patients and 31 gender- and age-matched healthy controls (HC) were included. The gray matter volume (GMV) changes in SCI patients were observed using voxel-based morphometry (VBM). Then, these altered gray matter clusters were used as the regions of interest (ROIs) for whole-brain functional connectivity (FC) analysis to detect related functional changes. The potential association between GMV and FC values with the visual analog scale (VAS), the American Spinal Injury Association (ASIA) score, and the course of injuries was investigated through partial correlation analysis.

Results

GMV of the frontal, temporal, and insular cortices was lower in the SCI group than in the HC group. No GMV changes were found in the primary sensorimotor area in the SCI group. Besides, the altered FC regions were not in the primary sensorimotor area but in the cingulate gyrus, supplementary motor area, precuneus, frontal lobe, and insular. Additionally, some of these altered GMV and FC regions were correlated with ASIA motor scores, indicating that higher cognitive regions can affect motor function in SCI patients.

Conclusions

This study demonstrated that gray matter and related network reorganization in patients with SCI occurred in higher cognitive regions. Future rehabilitation strategies should focus more on cognitive functions.
Papel Moderador do Afeto Interpessoal na Relação entre o Compromisso Prévio do Avaliador e Avaliação de Desempenho Subjetiva
Authors: Siqueira Diego Dantas , Lucena Wenner Glaucio Lopes
Published: October 2023

Esta pesquisa teve por objetivo analisar o efeito moderador do afeto interpessoal na relação entre o compromisso prévio do avaliador e avaliação de desempenho subjetiva. Como método foi utilizado o experimento 3x2 em uma amostra composta por 200 profissionais e acadêmicos da área de gestão. Os dados foram analisados com o auxílio do teste Mann-Whitney (U) e da regressão Tobit. Os resultados mostram que o compromisso prévio do avaliador e o afeto interpessoal influenciam de forma positiva e significativa a probabilidade de o gerente fornecer uma promoção ao funcionário. Na análise de moderação, verificou-se um efeito moderador positivo e significativo. Permitindo inferir que quando o gerente gosta do empregado, o compromisso com a decisão anterior afeta de forma mais acentuada na probabilidade de promoção deste funcionário. Em outras palavras, o gerente fica mais propenso a aumentar o comprometimento com a decisão escolhida. Contudo, verificou-se que os gerentes que foram a favor da promoção dos funcionários forneceram classificações de desempenho semelhantes aos gerentes que não participaram da contratação. Portanto, os resultados não apontam para a existência do viés de escalada do comprometimento no contexto analisado. Teoricamente esta pesquisa contribui ao inserir um novo construto comportamental no contexto do viés de escalada (afeto interpessoal). Do ponto de vista prático contribui ao fornecer evidências de como decisões anteriores interagem com o gosto do avaliador pelo subordinado para influenciar decisões futuras sobre avaliações de desempenho. Podendo ser úteis em auxiliar as empresas a aprimorar os sistemas de avaliação de desempenho, incorporando aspectos comportamentais dos tomadores de decisão.
Information Technology in the pecan nut production: case in Parana State, Brazil.
Authors: Franco Luciane Silva , Franco Antonio Carlos
Published: October 2023

O objetivo é avaliar a inserção da tecnologia da informação em propriedades dos produtores de noz-pecã da Região Oeste do Estado do Paraná, Brasil. Algumas lacunas de pesquisa na literatura de TI e mais especificamente na questão da produção de noz-pecã foram identificadas por Fronza et al., (2018), Barrios et al., (2010), entre outros. Esses autores afirmam que existem pesquisas sobre a inserção da TI no processo de produção de noz-pecã. Um questionário foi elaborado a 21 produtores de noz-pecã da Região Oeste do Paraná. Diferença significativa foi testada usando Kruskal Wallis em relação à idade do agricultor, tempo de trabalho, tamanho da propriedade e uso de tecnologia da informação (TI).O princípio 80/20 foi usado para apresentar as principais barreiras para os agricultores em relação ao uso de TI. Na análise PDCA, foram sugestões de melhoria contínua. Nos resultados, as diferenças no uso de TI nas propriedades dos produtores de noz-pecã são estatisticamente importantes nas variáveis de tamanho da propriedade e tempo de trabalho. O tamanho, o tempo de trabalho, o número de computadores, a terceirização de serviços de TI e a qualidade do acesso aos dados estão significando e positivamente correlacionados. A implicação é prática utilizar a implantação da TI nas empresas, como lente metodológica para avaliar o cenário dos produtores de noz-pecã da Região Oeste do Paraná.
The relationship between organisational culture, market orientation and organisational performance in the food and beverage sector
Authors: Oliveira Paulo Sergio Gonçalves de , Wada Elizabeth Kioko , Da Silva Talita Galli , Machado Claudia Leite , Mendes Denise Coelho
Published: October 2023

The article's objective was to evaluate how the organisational culture influences the market orientation and, consequently, the organisational performance of bars and restaurants in the city of São Paulo. To achieve the objective, the scale proposed by Jogaratnam (2017b) was adapted to the Brazilian reality and applied via Google Forms to professionals of bars and restaurants in the state of São Paulo, totalling 110 responses. Furthermore, the data were analysed by confirmatory factor analysis (PLS) through the SmartPLS version 3.2, which presented as significant the relationships between innovative culture and organisational performance, supportive culture and market orientation and organisational performance, demonstrating the aspects in which the food and beverage managers should pay attention to improve the performance of companies in the food and beverage sector, especially bars and restaurants.
DIVIDENDOS E CRISES: EFEITOS NAS EMPRESAS SUSTENTÁVEIS E DEMAIS COMPANHIAS DA B3.
Authors: Santos Murilo Alves , Ferreira Edson Alves , Júnior Miguel Hernandes , Rosa Arthur Antonio Silva , Ribeiro Karem Cristina De Souza
Published: October 2023

O objetivo do presente estudo foi identificar e analisar a distribuição dos dividendos das empresas listadas na B3 ao longo do período de 2010 a 2020 comparando as distribuições de dividendos das empresas certificadas no ISE com as não certificadas ao longo do período, especialmente nas crises econômicas. Amostra do artigo conta com 665 empresas listadas na B3, com uma média de 28 empresas ano com certificação ISE. O método utilizado foi regressão de dados em painel com efeitos fixos e em seguida pooled tobit. Como resultados não pode ser comprovada a relação entre certificação ISE em crises econômicas com a menor distribuição de dividendos, no entanto, demonstrou-se que empresas com certificação ISE são sinalizadoras ao mercado de estabilização na distribuição de dividendos (independente de crise financeira ou não). A limitação do estudo se refere ao período inicial restrito a 2010 em virtude da implantação do IFRS e como pesquisas futuras sugere-se a análise ser realizada como períodos dilatados a fim de se confirmar os resultados obtidos. A originalidade e as implicações na literatura, faz referência ao papel da certificação ISE na distribuição de dividendos, pois foi demonstrado que nem mesmo em épocas de severas crises financeiras estas organizações reduzem ou cortam os dividendos.
O PAPEL DO PROFESSOR E A NECESSIDADE DE ALFABETIZAÇÃO TECNOLÓGICA E CIENTÍFICA DOS JOVENS COM O AUXÍLIO DA CULTURA MAKER
Authors: Cascaes Nilcecleide Da Silva , Cavalcante Marisa Almeida
Published: October 2023

Existem várias teorias de aprendizagem que se podem usar em sala de aula, porém adequá-las ao século XXI e seus desafios na escola, têm sido alvo de vários estudos na sociedade contemporânea. A busca pela compreensão da aprendizagem e como melhorá-la deve considerar o mundo e os fatores sociais nos quais o indivíduo está inserido. É importante chamar a atenção que não basta “desenfileirar” as carteiras e colocar computadores, é preciso se repensar a relação ensino e aprendizagem sob novos parâmetros. Em tempos de internet, celulares e tablets, é bastante comum o uso destes dispositivos conectados a web de forma instrumental nas escolas. Papert (1985) nos traz uma proposta de como os computadores podem auxiliar na aprendizagem não somente como instrumentos, mas na construção de conceitos e modelos mentais, mesmo quando elas estiverem distantes fisicamente da tecnologia digital. Esta pesquisa é baseada nos conceitos de Papert e de como a Cultura Maker é um instrumento facilitador se aplicada no ambiente de ensino-aprendizagem e apresenta resultados referente à aprendizagem matemática assim como habilidades socioemocionais identificadas no decorrer da aplicação em uma escola pública.