bluuebunny/crossref_metadata_2025 huggingface dataset:
Application and Teaching Exploration of Virtual Reality Technology in Art Appreciation
Authors:   Assumption University, Bangkok, Thailand, Liu Pei
Published: October 2021

The combination of art class with VR (virtual reality) technology can realize the improvement of students' maximum subjective learning ability, and stimulate students' internal motivation to feel the pleasure and satisfaction of learning activities. At the same time, it can overcome the limitations of the teaching site, bring technical support for situational learning, visualize abstract problems in art teaching, and make theoretical thinking reliable. VR technology enriches art teaching content by enhancing the visualization and visualization of art works, and its authentic visual effect enables students to understand the three-dimensional dynamics and situational intention of sensory art works. It is not only a tool, but also an important carrier to inspire students to learn art initiative and explore art initiative. The application of VR technology in art teaching can avoid the shortcomings of traditional teaching, improve the quality and effectiveness of art education, and promote the development of education in the process of improving the effect and essence, which provides a new form for modern art teaching and realizes its qualitative leap.
An Empirical Research on the Application of Blended Learning Model in Higher Vocational Education in the Age of Internet
Authors:   Guangdong Vocational College of Posts and Telecom, Economic Management Institute, Guangzhou, China, Yanbing Liang
Published: October 2021

Blended learning which combined the advantages of traditional learning and digital teaching, provides a new way to improve the teaching level of colleges. Based on Internet thinking, this study explores the teaching effect of blended learning in higher vocational courses by teaching experimental research. The participants of the study are students majoring in marketing. Students in the experimental group received blended learning, while students in the control group received traditional learning. This research evaluates instructional effects by using the students’ learning achievements, learning interests, subject perceived value and course satisfaction. It is found that blended learning mode can significantly improve students’ academic performance and course satisfaction, enhance students’ learning initiative and participation, and meet the diversified teaching needs of vocational college students.
Survey on the Satisfaction of the Implementation of Individual Enrollment Arrangement for the Disabled in China
Authors:   School of Special Education, Leshan Normal University, No.778 Binhe Road, Central District District, Leshan City, Sichuan Province, China, Wang Zhen-zhou , Zhang Yang
Published: October 2021

A questionnaire survey was conducted on 974 college students with disabilities from 8 universities and colleges in 6 provinces to investigate their satisfaction with the implementation of Individual Enrollment Arrangement (IEA)for the disabled. The results show that the students with disabilities are less satisfied with the implementation of IEA, on the items of "teaching methods of high school" "Parent attitudes" "Parents' financial support" are more satisfactory. The relatively low degree of satisfaction are "the Number of higher special education institutions" "Enrollment majors" " Examination schedule" "Examination outline". In the future, the key reform of IEA for the disabled are to increase the number of higher special education institutions for the disabled, and expand the major of IEA, adjust the enrollment plan of college students with disabilities, and improve the implementation mechanism of IEA.
Methodological Learning Strategies Based on Disruptive Innovation in Research for Students of a Public University
Authors:   National University of San Martín-UNSM, Tarapoto, Peru, Padilla Manuel , López Ibis , Olivares Baldo , León Ana , Chauca Mario
Published: October 2021

The objective of the investigation was: To determine the effect of the application of the university investigation program to improve the investigation capacities in the students of cycle VIII, IX and X of the different faculties of the National University of San Martín-Tarapoto. From this perspective, it has been hypothesized that the application of a university research program produces significant effects in the improvement of research capacities in students of cycle VIII, IX and X of the various faculties of the National University of San Martín-Tarapoto. The explanatory study, of the experimental level, of the quasi-experimental design, has been carried out with a sample of 187 students from the various faculties of the UNSM-T. The comparison of the pre and post test scores, obtained from the students' responses, has allowed us to reject the null hypothesis and accept the alternative hypothesis, which shows that: The application of the university's research program significantly influences the improvement of research capacities, dimensions: Epistemological, methodological and transformational criticism of the students of the different faculties of the National University of San Martín-Tarapoto.
Desenvolvimento de jogos didáticos para o aprimoramento do raciocínio lógico e matemático voltado a construção de projetos arquitetônicos
Authors: Belinasso Giovanna Farias Feijó , Guesser Luiz Fernando , Nunes Ellen Casanova , Silveira Janaína Nones
Published: October 2021

O ensino de matemática atrelada a lógica e ao raciocínio é um grande desafio para alunos de arquitetura e urbanismo pois, embora relevantes e obrigatórios para uma adequada formação profissional, a maioria dos estudantes apresentam extrema dificuldade e/ou desinteresse em seus conteúdos. Visando desenvolver uma melhor estratégia de aprendizagem, esta proposta teve como objetivo criar uma nova estratégia de ensino por meio da elaboração e emprego de um jogo didático capaz de instigar o raciocínio lógico e matemático voltado à execução de projetos arquitetônicos. Para tal, foi inicialmente aplicado um questionário para os alunos da disciplina de lógica e raciocínio do curso de Arquitetura e Urbanismo da Universidade do Vale do Itajaí (UNIVALI) dos campi de Florianópolis e Balneário Camboriú. Em seguida, um jogo didático utilizando conceitos de sala de aula invertida e conteúdos matemáticos de nível médio e superior atrelados às aplicações práticas da futura vida profissional dos estudantes foi elaborado e aplicado. Os resultados obtidos demonstraram que 70% dos alunos relataram possuir dificuldade em matemática, sendo que 80% consideraram que os jogos didáticos podem ser uma alternativa viável para melhorar o aprendizado. Os resultados também demonstraram que o uso da metodologia de sala de aula invertida, associada aos jogos didáticos e a desafios matemáticos da futura vida profissional dos estudantes, podem se tornar ferramentas fundamentais para captar a atenção dos alunos, fato que pode contribuir para a aprendizagem e disseminação de conteúdos matemáticos e de raciocínio lógico considerados de maior complexidade. http://dx.doi.org/10.18226/23185279.v9iss2p41
Tratamento Superficial por Plasma em PVC Plastificado para Aplicações Decorativas por PVD
Authors: Pasqual Eduardo Radaelli , Soares Márcio Ronaldo Farias
Published: October 2021

A modificação superficial de materiais poliméricos tem levado a importantes avanços para a geração de novas aplicações industriais, além de permitir a substituição de polímeros de engenharia por materiais de custo menos elevado. Neste contexto, estudamos a modificação superficial de um sistema polimérico à base de PVC-DEHP, via tratamento por plasma de N2O2, aplicado a metalização decorativa por deposição física de vapor (PVD). Para este sistema estudado, análises por ATR-FTIR não revelaram alterações significativas na superfície do composto além da indicação da presença de hidroxilas (3200-3500cm-1), e alterações na região das carbonilas (1720cm-1) após a exposição ao plasma. Análises por AFM revelaram que a rugosidade superficial é aumentada, apresentando-se constante (46,59 ± 9,51nm) acima de 240 segundos de tratamento. Efeito similar de estabilização é observado em medidas de ângulo de contato, onde após uma redução em 36% em seu valor mantém-se constante (39° ± 4º) para tratamentos com tempos acima de 240 segundos, apresentando-se mais hidrofílica. Ensaios de adesão Pell Test sobre a camada metalizada indicam que o tempo de 240 segundos de tratamento por plasma foi o tempo mínimo para atingir uma adesão suficiente para este sistema, apresentando uma área de material removido inferior a 5%.  http://dx.doi.org/10.18226/23185279.v9iss2p47
Subconjunctival Loa Loa: A case report
Authors: Rashid Riffat , Sultana Sadia , Kadir Syeed Mehbub Ul , Haque Nazmul , Afzal Farzana
Published: October 2021

Loa loa is a nematode that is highly endemic in the tropical rainforests of Western and Central Africa. It is also known as “African eye worm”. Occasionally the adult parasite is seen in the subcutaneous tissue space of humans and occasionally into the subconjunctival space. Our case is a 29-year-old male presented to the outpatient department with history of swelling, redness and foreign body sensation in the inferior bulbar conjunctiva of his right eye. Slit lamp examination shows, a nodular swelling in the inferior conjunctival space and diagnosed as subconjunctival granulomatous lesion. In the operation theater, the lesion was explored and a live worm was removed from the subconjunctival space. The worm was measured about 3.5 cm in length. The worm was confirmed to be a Loa loa adult specimen. The patient was treated with 400 mg oral albendazole for 3 weeks and 60 mg prednisone. Ophthalmologists should be aware of the typical manifestations and possible unusual presentations. An increasing number of subconjunctival Loa loa cases are reported from non-endemic areas are due to increased travel and migration. This report illustrates an unusual ocular disease, which is usually not found outside of Africa, but easily diagnosed and treated.
Managing a bullet inside the orbit in lieu of a rifle – A video demonstration
Authors: Das Deepsekhar , Agrawal Sahil , Tripathi Manasi , Panigrahi Arnav , Gupta Saloni
Published: October 2021

Bullet injuries to the orbit are rare occurrences in a civilian’s life and are usually associated with severe ocular morbidity. The amount of damage inflicted by a bullet depends on various factors like the distance of the shooter from the victim, the speed of the bullet, the angle of impact, the site of damage, etc.

The authors here report a case where a male teenager presented to the ophthalmology casualty with a history of gunshot injury to his left eye. A foreign body was noted to be lodged in his left orbit on radiological imaging causing vitreous haemorrhage and traumatic optic neuropathy. The foreign body was then surgically removed from the orbit. It was the bullet of a rifle 3.2 cm long.

Intraorbital foreign body management must be tailored according to their type and location as well as to the clinical characteristics of the patient
The modern features of optimal therapy of cervical neoplasia on the background of bacterial vaginosis
Authors: Taran O.A. , Rud V.O. , Bulavenko O.V. , Konkov D.G.
Published: October 2021

Research objective: to evaluate the effectiveness of vaginal decametoxinum in preparation for cervix excision (conization) in women with HSIL (cervical intraepithelial neoplasia (CIN) II) against the background of infection with high-risk human papilloma virus (HPV) in bacterial vaginosis (BV) and effectiveness of vaginal gel with decametoxinum and hyaluronic acid to improve repair in the postoperative period.Materials and methods. 60 women with HSIL (CIN II) were examined against the background of high-risk oncogenic HPV infection and BV, who underwent loop cervix excision (conization). The main group (n = 30) on the eve of surgery was prescribed BV therapy with decametoxinum solution and oral metronidazole for up to 7 days, after cervical excision used vaginal gel with decametoxinum and hyaluronic acid for 14 days. The control group (30 patients) used oral metronidazole for 7 days for the BV treatment.Visual cervix inspection was performed by colposcopy. Vaginal biocenosis was assessed by PCR. Elimination of oncogenic HPV strains was assessed by PCR.Results. Decametoxinum in the combination therapy of HSIL (CIN II) caused faster and complete epithelialization of the wound surface than standard therapy (relative risk (RR) 0.27, 95% CI 0.10 – 0.71, p = 0.008). 3 months after decametoxinum use was determined by a significant increase in cases of vaginal microbiota normalization (RR 0.30, 95% CI 0.09 – 0.98, p = 0.047), an increase in the lactobacilli number in vaginal secretions (RR 0.31, 95% CI 0.11 – 0.84, p = 0.02). There was a statistically significant effect of decametoxinum on the oncogenic HPV elimination (RR 0.22, 95% CI 0.05 – 0.94, p = 0.04) after 6 months of combination therapy. No side effects of decametoxinum were noted either during therapy or at a later date.Conclusions. Vaginal use of decametoxinum before and after loop cervix excision in women with HSIL (CIN II) on the background of high-risk HPV and BV showed acceleration of cervical reparative processes, pronounced antimicrobial effect, elimination of oncogenic HPV and safety.
New opportunities for using transdermal forms of estradiol in ART programs
Authors: Kotlik V.V. , Grytsko M.I.
Published: October 2021

Objective of this review is to summarize the accumulated data on the use of estradiol transdermal gel in the form of a bottle with a pump-dispenser Oestrogel® in the treatment of "thin" endometrium and in assisted reproductive technologies (ART) programs."Thin" is the endometrium with thickness on ultrasound not exceeds 7 mm during ovulation and is characterized by complete or partial absence of conditions for ovum implantation. Endometrial thickness of 8 mm is referred to as hypoplastic endometriopathy. This endometrium thickness is used to predict the possibility of pregnancy in ART cycles.Estrogen and progesterone are the two main hormones responsible for morphological changes in the endometrial structure during the menstrual cycle. Estradiol promotes the expression of progesterone receptors, thus increasing the tissue sensitivity to progesterone.Today in Ukraine, oral and transdermal estrogens are widely used in ART programs. Transdermal estrogens are preferred due to their lack of a primary hepatic transit effect, which provides a higher safety profile compared to oral forms.A number of researches have been study the effectiveness of the Oestrogel®. It has been established that this drug is highly effective and safe for preparing patients for cryo-transfer of thawed embryos in ART programs. It has also been proven that the efficacy of estradiol transdermal gel in terms of pregnancy rate in patients treated in ART programs with gonadotropic releasing hormone antagonists is comparable to that of oral estradiol valerate and a transdermal patch. In another study, the frequency of miscarriages was significantly lower in patients treated with Oestrogel® compared with patients in the oral estradiol valerate group. Long-term pregnancy and live birth rates were also statistically significantly higher in the transdermal estradiol group. Conclusion. The estrogen drug Oestrogel® is an effective in improving the indicators of prolonged pregnancy and live birth. It can be effectively used for the treating "thin" endometrium and ART programs.
Comprehensive rehabilitation of patients of reproductive age with precancerous pathology of the cervix after organ saving surgeons
Authors: Rybin A.I.
Published: October 2021

The frequency of cervical dysplasia (cervical neoplasia) in the population is up to 5%, and in the structure of cervical diseases – 17–20%. Malignant transformation of the multilayered squamous epithelium is observed in almost 30% of patients with cervical dysplasia. The main surgical method of treatment of these conditions is diathermoconization of the cervix. But quite often patients have complaints in the late postoperative period. Comprehensive rehabilitation of patients of reproductive age with precancerous pathology of the cervix should include early restoration of sexual, reproductive and social functions of women. Research objective: to study the clinical effectiveness of the drug Femiclean (dequalinium chloride) in the comprehensive rehabilitation of patients with precancerous pathology of the cervix after organ-sparing surgery. Materials and methods. The first (main) group included 25 patients who, on the background of traditional treatment (broad diathermoconization of the cervix) for 6 days before and 12 days after treatment were treated with vaginal suppositories once a day Femiclean. The second (control) group consisted of 25 patients who underwent traditional treatment (broad diathermoconization of the cervix) with iodine-containing vaginal suppositories. Results. In patients of reproductive age with precancerous pathology of the cervix, who applied the developed concept of management in the postoperative period, the recurrence rate was probably lower; the epithelialization time was significantly higher than in women of the control group. The epithelialization time of the cervix in patients who used Femiclean vaginally in the pre- and postoperative period was 7.8 days faster compared to women who used standard vaginal drugs. The drug of domestic production Femiclean, according to our data, is well tolerated by patients and does not cause side effects.Conclusions. The developed complex rehabilitation of reproductive aged patients with precancerous pathology of the cervix after organ-sparing surgery has shown high clinical efficiency in comparison with traditional treatment this pathology.
The Pattern of Ear, Nose & Throat (Ent) Surgeries in A Secondary Health Centre in Enugu South Local Government Area of Enugu State Sourth-East, Nigeria
Authors: Anekpo Chijioke C. , Okpara Titus C.
Published: October 2021

There is a wide spectrum of ear, nose and throat surgical conditions affecting both children and adults in Nigeria.  This study aimed at determining the prevalence, socio-demographic features, types of ear, nose and throat surgical procedures in a secondary health centre in Enugu.
Patients and Methods:
This was a retrospective hospital based study of ENT clinic operation booking register and theatre operation register.  Data obtained were collated, documented and statistically analysed using SPSS version 20.0 software.
Result:
A total of 75 patients were operated at the centre during the period under review.  The female to male was 1:1:2.  The age range was from 1 year to 85years.  The indication for surgeries involving the throat were 67 (89.3%).  The nose 7(9.2%).  No surgery was performed in the ear.  Adenotosillectomy 52(69.3) was the commonest surgery performed is in throat while polypectomy 4(5.3%) occurred more in the nose.
Conclusion:
Resources for Ear, Nose and throat surgeries in Enugu South Local Government are grossly inadequate.  There is need for partnership with the Local Government administrator to upgrade the facilities.
Revisitando la indicación de la mastectomía profiláctica contralateral en pacientes con Síndrome de Li-Fraumeni y cáncer de mama. Reporte de un caso
Authors: Briceño-Morales Ximena , Briceño-Morales Clara , Guerrero-Macías Silvia Inés , Pedroza-Durán Ana María , Súarez-Rodríguez Raúl Alexis
Published: October 2021

Objetivo: describir el caso de una paciente con Síndrome de Li-Fraumeni (SLF) y cáncer de mama, en quien se cuestionó el beneficio en la supervivencia de la mastectomía profiláctica contralateral (MPC); asimismo, se pretende hacer una discusión crítica acerca de la evidencia que soporta este procedimiento en esta población.

Presentación del caso: mujer de 37 años con cáncer de mama y múltiples antecedentes familiares de cánceres de temprana aparición del espectro del SLF, en quien, durante la adyuvancia hormonal, se confirmó una variante patogénica en el gen TP53. La paciente fue presentada en la Junta Multidisciplinaria del Servicio de Mama de un Centro Oncológico de referencia en Colombia, con el fin de discutir el beneficio de la MPC. La decisión de la junta fue no realizar la MPC. Después de 30 meses de seguimiento la paciente se encuentra libre de enfermedad.

Conclusión: no existe evidencia que analice, de forma particular, el impacto de la MPC en la supervivencia de las pacientes con SLF y cáncer de mama. Sin embargo, a la luz del conocimiento actual no es posible generalizar la conducta de omitir esta cirugía profiláctica. Es importante reportar los casos en los que se decida realizar u omitir este procedimiento con el fin de incrementar el cuerpo de la evidencia, dado que existen limitaciones para construir grandes cohortes o estudios experimentales exclusivos para esta alteración genética.
Trust, Workload, Outdoor Adventure Leadership, and Organizational Safety Climate
Authors: Jackson Jeff , Harper Nevin , McLean Scott
Published: October 2021

The outdoor adventure leadership (OAL) field has an extensive body of work centered on individual safety performance, but much less at the organization level of analysis and assessment of organizational safety. Safety climate is a well-established construct and when measured can be indicative of employees’ perceptions of organizational safety and predictive of safety performance. This study employed a safety climate scale and surveyed 506 employees across ten United States OAL not-for-profit organizations. Dimensions of safety as a recognized value, and leadership and management for safety typically scored the highest across organizations. The Dimensions of safety as learning oriented, and safety as integrated into operations, typically scored the lowest. Trust in the organization and OAL delivery pressure, workload, and stress emerged as important indicators of safety climate at the organizational level. Directions for future research based upon this safety climate tool are identified.
Quality of Life and Behaviors of Bullies and Victims in an Iranian School Sample: The Moderating Role of Self-Esteem
Authors: Ghadampour Ezatolah , Khodarahimi Siamak , Heydariani Leyla , Barezgarbafrooyi Mahdi
Published: October 2021

The present study was undertaken to examine the relationship between quality of life in schools and the behaviors of bullies/victims in relation to the mediating role of self-esteem. A sample of 241 high school students was selected, within a correlational design, through the one-stage cluster sampling method, from Meybod City, Yazd Province, Iran. The Quality of Life Questionnaire in Schools (QLQS), the Rosenberg's Self-Esteem Scale (RSEE), and the Illinois Bully Scale (IUBS) were utilized in this study. The results indicate that the stated model has a goodness of fit index (GFI = 0.99 and root mean square error of approximation [RMSEA] = 0.06). The path analysis showed that the direct effects of the quality of life in schools on bullying and self-esteem are significant but not significantly on victimization. There was no significant effect of self-esteem on bullying, but a meaningful effect on victimization. Furthermore, the indirect effects on the quality of life in schools on bully/victims through self-esteem were significant.
Regional development in Russia's catching up innovation economy
Authors:   Yaroslavl state pedagogical university named after К. D. Ushinsky, Batrakova Ludmila G.
Published: October 2021

In the modern economy of Russia, an important role is played by technologies, which are given a significant place in the concept of innovative development. The fundamental direction of this development is research and development in the field of technologies, production of products, provision of services, which is the basis for the growth of the standard of living of the population. In view of the increasing role of territorial differentiation, the analysis of regional development in the catching-up innovative economy of Russia becomes relevant, since technological lag cannot but affect the efficiency of production. This is clearly demonstrated by the integrated ratings of socio-economic and scientific-technological development of the regions of the Russian Federation. The existing models of innovative development are based on the concepts of advanced and catch-up development. The Strategy of innovative development of Russia indicates that the country is focused on the re-equipment of the economy, based on imported technologies, which corresponds to the catch-up type of development. For Russia, the option of leadership in those segments of the economy where competitive advantages are created is possible, while advanced development should take place not only in the economic sphere, but also in the social sphere. The problem of catching up with innovative economic development is a new one that requires detailed study, both in theoretical and analytical aspects. In addition, special attention should be paid to the analysis of the possibilities of implementing the strategy of advanced and catch-up innovative development in the regions of Russia, as well as the creation of territories of advanced socio-economic development and special economic zones. In many regions of the Russian Federation, there are enterprises that produce world-class products that will allow them to be leaders. One of the most common areas of innovation activity in the regions is the introduction of new technologies in the housing and utilities system and transport infrastructure.
Milícias: o crime organizado por meio de uma análise das redes sociais | Militias: the crime organized by a social networking analysis
Authors: Couto Vinicius Assis , Filho Claudio Beato
Published: October 2021

Este artigo se propõe a analisar o fenômeno criminal das Milícias sob a ótica das análises de redes sociais. O trabalho está organizado em três partes. Primeiramente há uma tentativa de localizar o fenômeno estudado em uma determinada vertente conceitual, segundo a qual podemos tratar o fenômeno as milícias como ilustração de etapa de desenvolvimento de atividades criminais. A segunda parte tratará de uma caracterização do objeto de estudo, buscando compreender o contexto do tema a ser abordado. E, por fim, a terceira parte é dedicada a análise do objeto, em especial as características da rede que se articula nesta etapa de desenvolvimento das atividades criminais.
Editorial
Authors: Possani Maria Alice , Kopelman Isa Etel
Published: October 2021

A Edição Teatro e Comunidade II, em continuidade ao volume anterior, de dezembro de 2020, estende o dossiê temático com novos artigos, novas colaborações externas, fundamentais à existência da revista. Seguimos trabalhando em regime remoto há mais de um ano – rodeados de pressionamentos, revisões adiadas, datas acordadas com a revista dilatadas –, em um momento em que diversos periódico acadêmicos brasileiros anunciam a suspensão de suas atividades.
A network pharmacology approach to explore the potential role of Panax ginseng on exercise performance
Authors: Kim Jisu , Lee Kang Pa , Kim Myoung-Ryu , Kim Bom Sahn , Moon Byung Seok , Shin Chul Ho , Baek Suji , Hong Bok Sil
Published: October 2021

[Purpose] As Panax ginseng C. A. Meyer (ginseng) exhibits various physiological activities and is associated with exercise, we investigated the potential active components of ginseng and related target genes through network pharmacological analysis. Additionally, we analyzed the association between ginseng-related genes, such as the G-protein-coupled receptors (GPCRs), and improved exercise capacity.[Methods] Active compounds in ginseng and the related target genes were searched in the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). Gene ontology functional analysis was performed to identify biological processes related to the collected genes, and a compound-target network was visualized using Cytoscape 3.7.2.[Results] A total of 21 ginseng active compounds were detected, and 110 targets regulated by 17 active substances were identified. We found that the active compound protein was involved in the biological process of adrenergic receptor activity in 80%, G-protein-coupled neurotransmitter in 10%, and leucocyte adhesion to arteries in 10%. Additionally, the biological response centered on adrenergic receptor activity showed a close relationship with G protein through the beta-1 adrenergic receptor gene reactivity.[Conclusion] According to bioavailability analysis, ginseng comprises 21 active compounds. Furthermore, we investigated the ginseng-stimulated gene activation using ontology analysis. GPCR, a gene upregulated by ginseng, is positively correlated to exercise. Therefore, if a study on this factor is conducted, it will provide useful basic data for improving exercise performance and health.
PERBEDAAN TINGKAT KONSUMSI DAN KADAR KOLESTEROL DARAH ANTARA PEROKOK DAN NON PEROKOK
Authors: Fahmawati Dina
Published: October 2021

Cigarette smoke contains nicotine which disturbs health. Nicotine is capable of reducing the taste of food, so  there is appetite suppressant. The ability of nicotine in increasing blood liposuction process can affect the increase in blood cholesterol level. The research aims to study the difference between food intake and blood cholesterol level between smokers and non-smokers. This study was a comparative observational analytic study using cross-sectional design. The data of particular  subjects and smoking habit were  obtained from the questionnaire. The food intake was obtained by interview using 2x24 hours food recall form while the blood cholesterol level was obtained by blood sampling which was then analyzed using laboratory test. The subjects were 13 smokers and 13 non-smokers, taken by simple random sampling. The data were analyzed by Independent t-Test. The results have suggested that the difference in the average  food intake and  blood cholesterol level between smokers and non-smokers were not significant. The substantial average difference was found in the level of cholesterol intake, so  the statistical test has showed a significant difference, p-value = 0.005 < α(0.05). Smoking has a harmful effect for health so  people must decrease its consumption or stay abstinent from it. The longer human get exposed to cigarette, the more susceptible they get the illness from it.
GAMBARAN PERSEPSI PENYAKIT TERHADAP KESEHATAN FUNGSI PARU PADA PASIEN ASMA DI SURABAYA
Authors: Lorensia Amelia , Suryadinata Rivan Virlando , Ratnasari Richa
Published: October 2021

Asthma could affect quality of life and decrease productivity. The worsening of asthma symptoms also affected lung function. Symptoms of asthma could be control by self-management. The patient's behavior in self-management influenced by his perception of asthma.  This research aims to determine  effect of perception of disease on health function of parents in asma patients in surabaya. Research using observational methods with cross sectional design. Research Subjects were outpatient asthma patients aged 17-25 years. Data collection was conducted from June 2015 to January 2016 in Surabaya, to 27 people.  Assessment of asthma perception use Illness Perception Questionnaire (IPQ) and health condition of lung function with peak flow meter to assess PEF (peak expiratory flow). The results of this study indicate that both groups have a PEF value <50% of the estimated PEF value. The data showed no significant difference (p (0.766)> 0.05) between disease perceptions based on the number of asthma-related symptoms with lung function (PEF), with the greatest answer as the cause of asthma that is genetic. Therefore, the perception of asthma does not affect lung function (PEF) in adult asthma patients in Surabaya.
INVESTIGATION OF THE FEATURES OF NICKEL-MODIFIED MORDENITE ZEOLITES
Authors: Patrylak Lyubov , Voloshyna Yuliya , Pertko Olexandra , Yakovenko Anzhela , Povazhnyi Volodymyr , Melnychuk Oleksandr
Published: October 2021

Zeolites are wide used materials in a range of processes of chemical, petrochemical, and nutritional industry. They are the active catalysts and sorbents, in particular, zeolites are characterized by high efficiency towards extraction of heavy and radioactive metals from the aqua medium. An important factor of high zeolite catalyst activity is preserving the integrity of the crystal structure. The purpose of this research was to check out the features of MOR zeolite modifications with nickel by means of low temperature nitrogen adsorption/desorption, IR-spectroscopy, and X-Ray Diffraction (XRD). Using ion exchange and following calcination the hydrogen form of zeolite was obtained. The last was impregnated by nickel in quantity of 1, 5, and 15 wt. %. The investigations of nickel-modified samples demonstrated that MOR-type zeolite was relatively resistant to the used manipulations. However, the hysteresis loops of their isotherms are observed. The last can be connected with mesoporosity appearance.  The degree of zeolite destruction is found out to increase with rise of nickel content in the samples. Based on IR spectra analysis by means of checking out the ratio between intensity of bands at 560 and 440 cm-1 using Gaussian function in Origin medium the same conclusions were drawn. Crystalline structure of mordenite was confirmed by using XRD method, but minor quantitative destruction cannot be recognized without application of methods of the internal and external standards.
Influence of ultraviolet radiation on kinetic characteristics in erythrocytes
Authors: Almazova Оlena , Lysychenko Mycola
Published: October 2021

Erythrocytes were irradiated with an ultraviolet lamp of the VMT type (λ = 253.7 nm). The kinetic characteristics in irradiated and non-irradiated blood samples were compared by the acid (chemical) erythrogram method and by the counter transport method. Obtained:

- by the method of acidic erythrograms it was found that in ultraviolet-irradiated blood samples there is a decrease in the time of half hemolysis.

 - ultraviolet radiation increases the speed of counter movement of ions through erythrocyte membranes.

- a decrease in the time of half hemolysis and an increase in the rate of counter transfer of ions, irradiated blood samples, is due to a decrease in the "effective" thickness of the near-membrane diffusion layer - an immiscible layer of water adjacent to the erythrocyte membrane.

A decrease in the "effective thickness" of the near-membrane water layer changes the rate of metabolic processes in the "cell - intercellular medium" system, changing the mode of cell functioning. The altered mode of functioning is a biological response to light radiation. Red blood cells with an altered mode of functioning are stimulus signals that force the body to mobilize resources to fight pathology. These circumstances can predict the creation of a universal phototherapeutic equipment for extracorporeal blood irradiation based on LEDs with certain exposure parameters. Figs.: 4. Tabl.: 3. Refs.: 12 titles.
Buku Ajar Cyber Public Relation
Authors: Febriana Poppy
Published: October 2021

Alhamdulillah, segala puji bagi Allah SWT atas limpahan rahmat dan karunia-Nya, penulis dapat menyelesaikan Buku Ajar Cyber Public Relation ini. Selama ini penulis merasa masih minimnya referensi buku terkait Cyber Public Relation yang tersedia sehingga penulis tertarik untuk mulai menulis buku ajar ini dengan mengumpulkan beberapa referensi. Terlepas dari upaya tersebut penulis menyadari bahwa buku ajar ini masih jauh dari kesempuarnaan sehingga mungkin akan membutuhkan perbaikan seiring dengan semin bertambahnya keilmuah Public Relation di dunia digital. Akhirnya, penulis mengucapkan terimakasih yang sebesar-besarnya kepada semua yang terlah terlibat dan membatu dalam penyusunan buku ajar ini. Penulis juga mohon maaf yang sebesar-besarnya atas kesalahan yang terdapat dalam buku ajar ini. Sebagai upaya terus memperbaiki dan meningkatkan kualitas buku ajar ini, penulis menerima kritik dan saran yang membangun. Selanjutnya, penulis ucapkan selamat membaca.
Environmental and anthropogenic influences of movement and foraging in a critically endangered lemur species, Propithecus tattersalli: implications for habitat conservation planning
Authors: Semel Meredith A , Abernathy Heather N , Semel Brandon P , Cherry Michael J , Ratovoson Tsioriniaina J , Moore Ignacio T
Published: October 2021

BackgroundWildlife conservation often focuses on establishing protected areas, however, these conservation zones are frequently developed without adequate knowledge of the movement patterns of the species they are designed to protect. Understanding movement and foraging patterns of species in dynamic and diverse habitats can allow managers to develop more effective conservation plans. Threatened lemurs in Madagascar are an example where management plans and protected areas are typically created to encompass large, remaining forests rather than the resource needs of the target species. MethodsTo gain an understanding of golden-crowned sifaka ( Propithecus tattersalli ) movement patterns, including space use and habitat selection, across their range of inhabited forest types, we combined behavior data with Dynamic Brownian Bridge Movement Models and Resource Selection Functions. We also examined the influence of abiotic, biotic, and anthropogenic factors on home range size, movement rates, and foraging patterns. ResultsWe found that home range size and movement rates differed between seasons, with increased core area size and movement in the rainy season. Forest type also played a role in foraging behavior with lemur groups in humid forest avoiding roads in both seasons, groups in the dry deciduous forest avoiding road networks in the rainy season, and groups in the moderate evergreen forest displaying no selection or avoidance of road networks while foraging. ConclusionOur study illustrates the importance of studying primate groups across seasons as well as across forest types, as developing conservation plans as a single snapshot can give an inaccurate assessment of their natural behavior and resources needs. More specifically, by understanding how forest type influences golden-crowned sifaka movement and foraging behavior, we can make conservation management plans specific to the individual forest types they inhabit (humid, moderate evergreen, dry deciduous, littoral, etc.), rather than the region as a whole.
Effect of different interventions for latent tuberculosis infections in China: a model-based study
Authors: Wen Zexuan , Li Tao , Zhu Wenlong , Chen Wei , Zhang Hui , Wang Wei-bing
Published: October 2021

Background

Tuberculosis (TB) has a serious impact on people’s health. China is one of 30 countries that has a high TB burden. As the currently decreasing speed of the incidence of TB, the WHO’s goal of “End TB Strategy” is hard to achieve by 2035. As a result, a dynamic model that determines the impact of different tuberculosis preventive treatments (TPTs) in different age groups, and the effect of different interventions on latent TB infections (LTBIs) in China is developed.
Methods

A Susceptible-Exposed-Infectious-Recovered (SEIR) model was established. Goodness-of-fit tests were used to assess model performance. Predictive analysis was used to assess the effect of different interventions on LTBIs and achieving the goals of the “End TB Strategy”.
Results

The chi-square test indicated the model provided a good statistical fit to previous data on the incidence of TB (χ2 = 0.3085, p > 0.999). The 1HP treatment regimen (daily rifapentine + isoniazid for 4 weeks) was most effective in reducing the number of TB cases by 2035. The model indicated that several strategies could achieve the 2035 target of the “End TB Strategy”: completion of active case finding (ACF) for LTBI and TPT nation-wide within five years; completion of ACF for LTBIs and TPT within two years in high-incidence areas; completion of TPT in the elderly within 2 years; or introduction of a new vaccine in which the product of annual doses and vaccine efficiency in each age group reached 14 million.
Conclusions

The incidence of TB in China declined gradually from 2005 to 2019. Although China have made a lot of efforts in TB prevention and control, there is still a long way to attain the 2025 and 2035 target of “End TB Strategy” with the present preventive interventions. Implementation of ACF for LTBIs and TPT nation-wide or in areas with high incidence, in the elderly, or administration of a new and effective vaccine could greatly reduce the number of TB cases and achieve the 2035 target of the “End TB Strategy” in China.
Ivermectin for COVID-19: addressing potential bias and medical fraud
Authors: Hill Andrew , Mirchandani Manya , Pilkington Victoria
Published: October 2021

Ivermectin has become a controversial potential medicine for COVID-19. Some early studies suggested clinical benefits in treatment and prevention of infection. However, the body of evidence includes studies of varying quality. Furthermore, some trials have now been identified as potentially fraudulent. We present a sub-group analysis, to assess the effects of stratifying by trial quality on the overall results. The stratification is based on the Cochrane Risk of Bias measures (RoB 2) and analysis of raw data where possible. The results suggest that the significant effect of ivermectin on survival was dependent on largely poor quality and potentially fraudulent studies. This highlights the need for rigorous quality assessments, the need for authors to share patient level data and efforts to continue to avoid publication bias for registered studies. These steps are vital to facilitate accurate conclusions on any clinical treatment.
The Toxicity of Polyethylene Microplastic Exposure and Its Concurrent Effect With Aeromonas Hydrophila Infection To Zebrafish
Authors: Ding Ning , Jiang Lin , Wang Xiao , Wang Chun , Geng Yue , Zhang Jianxin , Sun Yingxue , Zhang Yanping , Yuan Quan , Liu Hong
Published: October 2021

Microplastics that are widely distributed in the environment has raised great concerns due to their potential negative effects to humans. Zebrafish was used as the model organism in this study to assess the toxicity of microplastic exposure. The adult zebrafish were exposed to the PE microplastics in smooth clustered sphere shapes with diameters of 75-100 µm for 35 days, and the survival rate of the zebrafish were not significantly affected, whereas the growth rate was. Further analyses on the oxidative stress related enzyme activities showed that the production of GSH, GSH-PX, and GST in the intestine were stimulated when exposing to the microplastics of lower concentrations (0.1 and 1 mg/L), while the production of SOD, CAT, GSH, GSH-PX were suppressed when exposing to those of 10 mg/L. The activities of enzymes in the muscle were much less affected. The intestinal injury and changes of colony structure in the intestine were observed by exposure to the tested concentrations of microplastics. By exposure to the microplasctics for 35 days, a further concurrent exposure to microplasctics and Aeromonas hydrophila did not exacerbate the mortality of zebrafish due to bacterial infection; on the contrary, the mortality was reduced. This study confirmed the intestinal enzyme activity changes of zebrafish, but showed no sign of inducing higher mortality or exacerbating bacterial infection by chronic exposure to the microplastics.
Transcranial direct current electrical stimulation in combination with aerobic exercise is effective in reducing fatigue and pain in post-COVID-19 systemic autoimmune rheumatic patients
Authors: Missé Rafael Giovane , Santos Alexandre Moura dos , Borges Isabela Bruna Pires , Simões Marlise Sítima Mendes , Silva Lorenza Rosa Silverio , Correia Bruna Lindoso , Kim Ana Wook Sook , Caetano Aline Marques , Pasoto Sandra Gofinet , Saad Carla Gonçalves Schahin , Domiciano Diogo Souza , Tanaka Clarice , Greve Júlia Maria D’Andrea , Baptista Abrahão Fontes , Shinjo Samuel Katsuyuki
Published: October 2021

Objectives: Currently, no studies have assessed the efficacy of transcranial direct current stimulation (tDCS) to treat fatigue and pain associated with or potentiated by post-COVID-19 syndrome in patients with systemic autoimmune rheumatic diseases (SARDs). Methods: This study included nine patients with different types of SARDs. All patients had previously confirmed RT-PCR test for COVID-19 as well as significant, persistent fatigue and pain that began to worsen after infection. Anodal tDCS was administered in five daily sessions (2mA, 20 minutes) over the C3 or C4 10/20 EEG positions, with the cathode placed at Fp1 or Fp2. Concomitantly, patients were involved in an aerobic exercise program by treadmill walking. All participants were evaluated using specific questionnaires and strength assessment by handgrip and physical function by timed-up-and go test and sit-to-stand test at baseline (within one week before tDCS protocol), and one week after tDCS protocol. During all procedures, the patients’ treatments remained unchanged. Results: The sample was composed of eight women and one man with a mean age of 48.7±9.6. After the tDCS protocol, the pain and fatigue significantly improved by a visual analog scale (P<0.05). The physical function also improved 9.5±2.7 vs. 6.8±0.8 (P=0.001) for timed-up-go-test and 10.3±3.7 vs. 15.1±4.0 (P=0.037) for sit-to-stand test. No subject experienced adverse events. One-hundred percent of patients adhered to all protocols. Conclusions: The present study showed tDCS in combination with aerobic exercise was effective in improving the physical function, and reducing fatigue/pain in SARDs patients with post-COVID-19 syndrome.Clinical Trials: NCT04890483.
A GIS-Based Assessment of Active Tectonics from Morphometric Parameters and Geomorphic Indices of Assam Region, India
Authors: Gupta Laxmi , Agrawal Navdeep , Dixit Jagabandhu , Dutta Subashisa
Published: October 2021

Assam region lies in the tectonic region of eastern Himalayas and flood plains of River Brahmaputra. The landscape of Assam is formed by the complex integration of the vertical and horizontal movement of the earth’s crust and the depositional and erosional process by a river. The frequency of seismic events results in the deformation of landforms and it highly influences the drainage pattern of the area. The analysis of tectonic or neotectonic activity with the help of morphometric parameters and geomorphic indices helps in the identification of hazard-prone areas of the basin. In the present study, the active tectonics of the Assam region is assessed using SRTM DEM data of 30 m resolution to derive linear and aerial morphometric parameters and eight geomorphic indices of the selected ten basins. The morphometric parameters and geomorphic indices namely, stream length gradient (Sl), valley floor width to height ratio (Vfh), hypsometric curve, hypsometric integral (Hi), asymmetric factor (Af), basin shape index (BS), transverse topographic symmetry (T), basin elongation ratio (BE) and stream sinuosity (SS) are calculated for each basin. With the help of GIS, the indices are classified into three tectonic activity classes i.e., from higher to lower and the average of the classes are combined to generate an index of relative active tectonics (IRAT). The four classes of IRAT are defined for the study area as i) very high; Class 1 (1.57 – 1.80), ii) high; Class 2 (1.81 – 2.06), moderate; Class 3 (2.07 – 2.26) and low; Class 4 (2.27 – 2.30). Class 1 of IRAT corresponds to Basin 1 and 6 with a total area of about 47740 km2, basin 2, 4 and 5 falls under Class 2 of IRAT and its total area is 2507 km2, class 3 covers a total area of 17495 km2 of basin 7,8 and 9 and Class 4 IRAT consists of basin 3 and 10 of total area 2090 km2. Results show that the majority of the study area lies in very high to moderate active tectonic zones and these zones are consistent with the presence of major faults and thrusts of the basin area. It can be concluded that the combined approach of GIS-based morphometric and geomorphic study of a region allows in the identification of deformed landforms resulting from active tectonics.