bluuebunny/crossref_metadata_2025 huggingface dataset:
Brief historical excursion of Orthodoxy in Bashkortostan: conditions and features of distribution among the peoples of the Republic
Authors:   Institute for Ethnological Studies named after R.G. Kuzeev UFRC RAN, Efimov D.A.
Published: March 2023

The history of the spread of Orthodoxy on the territory of Bashkortostan is considered, three main stages are identified: 1) from the middle of the XVI century to the October Revolution of 1917, 2) from 1917 to the end of the 1980s, 3) from the end of the 1980s to the present. Special attention is paid to the conditions and peculiarities of the spread of Orthodoxy among the peoples of the republic, as well as missionary activities among followers of Islam and traditional ethnic religions. Statistical data on the number of believers-Orthodox, religious buildings of the Russian Orthodox Church are given.
Topological reflection of media reality: from image to text
Authors:   Kuban State Agrarian University named after I. T. Trubilin, Enikeev A.A.
Published: March 2023

The article is devoted to the study of media reality. The thesis is postulated that media reality has a special spatial logic of its development. Media reality, according to the views of modern analysts, is located in the space between the text and the image. One of the productive methods of its study is topological reflection. This type of reflection includes the problem of positioning the researcher himself in the text and language. It is concluded that the «iconic turn» of modern mass culture requires its own textual analysis by means of philosophy.
«Futures studies» as a complex of scientific directions for the study of the future
Authors:   Gorlovka Institute for Foreign Languages, Rochnyak E.V.
Published: March 2023

The subject of this article is a number of scientific directions of studying the relationship between the present and the future, combined into a single system of «Futures studies». The analysis of the sources allows us to conclude that to a large extent these directions are based on modern achievements in the field of psychology, and their common main idea is to build a person's own participatory future.
CENTENARIANS IN THE DEMOGRAPHIC STRUCTURE OF THE RUSSIAN POPULATION
Authors:   Novosibirsk State Medical University ", Goroshko N.V. ,   NGMU",   , Novosibirsk, Russia, Patsala S.V. ,   Novosibirsk State Pedagogical University "NGPU", Novosibirsk, Russia
Published: March 2023

The subject of the study is a cohort of the Russian population aged 90+ (centenarians). The purpose of the work is to conduct a theoretical study of the place of the cohort of centenarians in the demographic structure of the country's population. The relevance of the study is due to the fact that longevity is still a fairly rare phenomenon, attracting the attention of many specialists. The iden- tification of its determining factors remains an important medical, social, and state problem. Today there is no universal answer to the question "what determines the level of longevity?". In light of the search for an answer to it, it is necessary at least to give an accurate picture of longevity in Russia, both on the national scale and in the context of its regions. The scientific novelty consists in identifying the level of longevity in Russia and the spatial pattern of the spread of this phenomenon on the territory of the country. The statistical data of the Federal State Statistics Service, as well as analytical publications in periodicals, served as the information base of the study. The research methods include general logical, analytical, statistical, and cartographic methods. To measure the level of longevity, such indicators were used (including calculated) as the absolute number of centenarians (persons aged 90+); the proportion of centenarians (aged 90+) in the total population; the index of longevity or longevity for groups aged 90+. In the course of the study, the authors obtained the following results: indicators of the level of longevity in Russia and in its regions were determined. In order to visualize the obtained regional data, their mapping was carried out. Factors influencing spatial differences in the level of longevity in the country have been identified. The authors conclude about the positive dynamics of the longevity level of the population of Russia in 1990-2021. Among the macro-regions of Russia, the Central Federal District is the leader in terms of the absolute number of cen tenarians, their share in the total population, and the value of the longevity index. The Far Eastern Federal District is an outsider according to these parameters. At the same time, the territories that in Russia are traditionally considered “hotbeds” of longevity – the North Caucasus and Siberia – do not show high values of longevity indicators. Outsider regions in terms of the longevity of the population are mainly “areas of new development”.
COMMERCIALIZATION OF PROFESSIONAL EDUCATION IN RUSSIA FROM THE PERSPECTIVE OF WORKFORCE TRAINING
Authors:   Voronezh State University, Voronezh Institute of High Technologies, Voronezh, Russia, Kolesnikova O.A. , Maslova E.V. ,   Voronezh State University, Voronezh Institute of Economics and Social Management, Institute of Social Education, Okolelykh I.V. ,   Voronezh Institute of High Technologies, Voronezh, Russia
Published: March 2023

The subject of the research is changes in the training of the workforce in the field of higher and secondary vocational education due to the growth of its commercialization. The purpose of the work is to analysis of quantitative and structural changes occurring in these conditions, identification of their causes and evaluation of the results. The relevance of the study is due to the need for a comprehensive analysis of the impact of commercialization on the development of the professional aspect of education. The scientific novelty consists in the theoretical substantiation of the social essence and approaches to the development of education in a mixed economy, determining the role of commercialization among modern factors influencing professional education, and identifying its positive and negative results. Methods of factor and statistical analysis, sociological surveys, comparative logic, systematization, normative (prescriptive) modeling, etc. are used in the study. Based on the results of the study, the authors came to the following conclusions: current professional education in Russia is a mixed public good that has two forms of expression: free, state-guaranteed, as well as private, commercial; the terminological identification of a good that forms and develops a person with one of the services acquired by a person distorts the meaning of this relationship. The nature of the relationship between property relations, opportunities, and real trends in the financing of professional education in Russia is revealed. The assessment of the role and contribution of the commercial sector by levels and types of professional training of the workforce is given. All the pros and cons of the commercialization of professional education in the country are analyzed, and its impact on the level of its development and changes in its structure is revealed. The main problems in the area under consideration are systematized, and approaches to their solution are outlined.
A Primer in Precision Nephrology: Optimizing Outcomes in Kidney Health and Disease through Data-Driven Medicine
Authors: Jayaraman Pushkala , Crouse Andrew , Nadkarni Girish , Might Matthew
Published: March 2023

This year marks the 63rd anniversary of the International Society of Nephrology, which signaled nephrology's emergence as a modern medical discipline. In this article, we briefly trace the course of nephrology's history to show a clear arc in its evolution—of increasing resolution in nephrological data—an arc that is converging with computational capabilities to enable precision nephrology. In general, precision medicine refers to tailoring treatment to the individual characteristics of patients. For an operational definition, this tailoring takes the form of an optimization, in which treatments are selected to maximize a patient's expected health with respect to all available data. Because modern health data are large and high resolution, this optimization process requires computational intervention, and it must be tuned to the contours of specific medical disciplines. An advantage of this operational definition for precision medicine is that it allows us to better understand what precision medicine means in the context of a specific medical discipline. The goal of this article was to demonstrate how to instantiate this definition of precision medicine for the field of nephrology. Correspondingly, the goal of precision nephrology was to answer two related questions: (1) How do we optimize kidney health with respect to all available data? and (2) How do we optimize general health with respect to kidney data?
A RESPONSABILIDADE CIVIL DO ESTADO POR DANOS DECORRENTES DE ATOS JUDICIAIS
Authors: ARAUJO TEIXEIRA DA SILVA RAPHAELA
Published: March 2023

The civil liability of the State for damages resulting from legal acts is a hotly debated subject within the scope of jurisprudence and doctrine. In summary, it discusses the possibility or not of state liability in damages actions that deal with damages resulting from legal acts, whether due to judicial acts or jurisdictional acts. For a better understanding of the topic addressed, the work will analyze all aspects involving the theme.
Bisturí de doble hoja: una opción para la técnica en espagueti con inclusión en parafina para lentigo maligno
Authors: Pulido- Prieto Leonardo , Jaimes Ramirez Ángel Omar , Barrera Juan Camilo
Published: March 2023

El abordaje quirúrgico del lentigo maligno es un desafío para los dermatólogos, dada la dificultad para delimitar los bordes de la lesión. En el manejo quirúrgico del lentigo maligno, se ha empleado la escisión de los bordes visibles mediante la técnica en espagueti con inclusión en parafina para el análisis histopatológico de los bordes antes de la resección definitiva del tumor.
Se expone el uso de la técnica de bisturí de doble hoja para optimizar el tiempo quirúrgico y obtener una pieza más homogénea, usando los materiales ya disponibles y sin aumentar los costos.
Tumores renales de pacientes con riñones en herradura: reporte de 2 casos clínicos
Authors: Becerra Luis Miguel , Dominguez Bellini Cristina , Ramos Ulloa Jose Gustavo , Cabrera Fierro Marino , Forero Jorge Alfredo , Ramírez Ramírez Angie , Varela Rodolfo
Published: March 2023

El riñón en herradura (RH) es la anomalía congénita de fusión renal más común. La incidencia del tumor de células renales en riñón en herradura es similar a la de los pacientes con riñones de estructura normal; en cambio, el riesgo de desarrollar cáncer de células transicionales aumenta entre 2 a 6 veces. La presencia de cualquier malformación renal puede cambiar el plan de tratamiento quirúrgico y se busca realizar una cirugía con preservación de órgano. Se describen 2 casos clínicos de tumores (carcinoma renal de células claras y tumor urotelial) en riñones en herradura llevados a heminefrectomía radical abierta y laparoscópica.
Crisis blástica aislada del sistema nervioso central en la leucemia mieloide crónica en tratamiento con dasatinib. Reporte de un caso y revisión de la literatura
Authors: Martínez-Cordero Humberto , Ramos-Córdoba Roberto Andrés , Gaitán-Aroca Rafael , García-Buitrago Andrea , Chinchilla Sandra , Bedón Giovana , Novoa-Caicedo Isabella
Published: March 2023

La leucemia mieloide crónica (LMC) es unaenfermedad que se presenta en tres fases: crisis crónica, acelerada y blástica. El diagnóstico de crisis blástica se establece cuando hay 20% o más de blastos en la médula ósea o infiltración extramedular de blastos, frecuentemente en forma de sarcoma mieloide. La crisis blástica aislada del SNC es muy rara y más aún en pacientes tratados con dasatinib que tiene buena penetrancia a este nivel. Presentamos el caso de un paciente de 61 años con diagnóstico a largo plazo de LMC, en tratamiento con dasatinib, manteniendo una respuesta molecular mayor, que consultó por cefalea y convulsiones, descartando causas anatómicas e infecciosas. El análisis de LCR mostró la presencia de blastos con una biopsia de médula ósea normal que llevó al diagnóstico de crisis blástica aislada del sistema nervioso central. Se continuó el tratamiento con dasatinib a una dosis más alta y se estableció un régimen de quimioterapia intratecal con reservorio de Ommaya con excelentes resultados. La crisis blástica aislada del sistema nervioso central es rara, en la mayoría de los casos se ha notificado bajo tratamiento con imatinib, que tiene baja penetrancia a este nivel. Solo hay un caso en la literatura de crisis blástica tratada con dasatinib y es de origen linfoide. El manejo no está bien establecido debido a la literatura limitada sobre el tema. Se requieren estudios multicéntricos para delinear un tratamiento adecuado en este tipo de casos.
Bioenergy Focused Smart Specialisation Potential in İzmir Within the Scope of Tackling Climate Change
Authors: ÇELİK Halil İbrahim Murat , KOCAR Günnur
Published: March 2023

Climate change is seen as one of the foremost risks to the sustainable future of the world and humanity, and its negative effects are increasing from day to day. Energy production and usage are the biggest cause of global greenhouse gas emissions, which is one of the main factors of climate change. Therefore, energy is one of the primary areas that should be focused on in tackling climate change. This negative effect of energy on climate change results in an increase in efforts and investments toward clean energy conversion all over the world. Countries and cities that want to accelerate their development by growing in competitive and high-value-added sectors see this situation as an important economic opportunity at the same time. As one of the main clean energy sources, bioenergy is one of the important sectors in the world's clean energy transformation. Regions and cities in Europe carry out smart specialisation studies to use their bioenergy potential and try to accelerate their regional development. In this study, the bioenergy focused smart specialization potential in İzmir was evaluated according to the Good Smart Specialization Practice Criteria of the European Union Smart Specialization Platform (S3 Platform). The evaluation was made qualitatively using the gap analysis method considering data gathered from the literature search. As a result of this interdisciplinary study in the fields of regional development and clean energy, suggestions for a bioenergy focused smart specialisation implementation in İzmir were presented.
Štípaná industrie z pohřebiště únětické kultury v poloze Podolí – Příčný (okr. Brno-venkov) jako indikátor sociálních jevů
Authors: Kaňáková Ludmila , Parma David
Published: March 2023

Příspěvek se zabývá komplexní analýzou souboru štípané industrie z několikaletého záchranného výzkumu v poloze Podolí – Příčný, pocházejícího z hrobů i sídlištních objektů. Zahrnuje dosud nejpočetnější kolekci štípané industrie z funerálního kontextu únětické kultury na Moravě s detailní terénní dokumentací. Významné jsou vzhledem k poloze pohřebiště v blízkosti surovinového zdroje informace o používané surovině, a dále zmapování výskytu technologických a morfologických jevů, které známe ze štípané industrie ze soudobých sídlišť. Nezanedbatelnou roli v analýze štípané industrie z funerálního kontextu hraje i funkční a traseologická analýza provázaná s výsledky analýzy antropologického materiálu. Výsledky naznačují genderové rozdíly v používání kamenné štípané industrie resp. jejího ukládání do mužských a ženských hrobů. Profiluje se zde také relativně úzká část populace únětické kultury s intenzivnějším vztahem k tradici kamenné industrie a jejím potencionálně symbolickým morfotypům.
Analýza zvířecích kostí z epigravettienské lokality Brno-Štýřice III, výzkumné sezóny 2012–2014
Authors: Roblíčková Martina , Nerudová Zdeňka , Nývltová Fišáková Miriam
Published: March 2023

V letech 2009 a 2011–2014 proběhl záchranný archeologický výzkum epigravettienské lokality Brno-Štýřice III, známé od roku 1972 jako Koněvova či Vídeňská. Vedle kamenné industrie byl při výzkumu nacházen i zvířecí osteologický materiál, který je postupně analyzován a publikován. Zvířecí kosti získané výzkumy v letech 2012–2014 jsou hlavním tématem předloženého článku. Byla provedena jejich druhová determinace a určen minimální počet jedinců (MNI), nicméně vysoká fragmentárnost kostí, způsobená částečně i jejich užíváním jako paliva, determinaci komplikovala. Součástí jsou také výsledky izotopových analýz C, N a Sr a analýza sezonality. Zjištěné druhové složení fauny s dominancí mamuta srstnatého naznačuje chladné glaciální klima, tento výsledek podporují i analýzy izotopů C a N. Plošná distribuce zvířecích kostí odpovídá hlavním koncentracím kamenné štípané industrie, několik tisíc přepálených drobných fragmentů kostí kumulovaných na malé ploše jasně dokládá paleolitické ohniště. Jednotlivé výsledky včetně radiokarbonového datování a rozboru kamenné štípané industrie kladou pozici lokality do samého závěru posledního glaciálního maxima.
Pendapatan Usahatani Kelapa Di Desa Jiko Belanga Kecamatan Nuangan Kabupaten Bolaang Mongondow Timur
Authors: Mangoli Agreishe Septaharani , Katiandagho Theodora Maulina , Porajow Oktavianus
Published: March 2023

This study aims to calculate the income of coconut farming in Jiko Belanga Village, Nuangan District, East Bolaang Mongondow Regency. This research was conducted during September 2022. The data used in this research are primary data and secondary data. Primary data was obtained through direct interviews with 10 respondents using a questionnaire. And secondary data obtained through books, journals, and literature related to this research topic. The results of this study indicate that the average income received by the farmers of Jiko Belanga Village, Nuangan District, East Bolaang Mongondow Regency with coconut farming for one harvest/per quarter (3 months) with copra production of IDR4,956,517. and income per hectare is IDR2,065,215.
Analisis Keuntungan Usaha Pedagang Sayur Di Pasar Pinasungkulan Karombasan Kota Manado (Studi Kasus Pada Pedagang Sayur Sawi Putih, Wortel Dan Kubis)
Authors: Givethee Audina , Kumaat Ribka Magdalena , Benu Noortje Marselianie
Published: March 2023

This study aims to analyze the profits of vegetable traders in the Pinangsungkulan Market, North Karombasan. The research was carried out for 3 months, from March to May 2020. The research was conducted at the North Karombasan Pinasungkulan Market. This research uses primary data and secondary data. Primary data was obtained through interviews using a questionnaire (questionnaire) to vegetable traders at Pinasungkulan Market, North Karombasan. Secondary data was obtained from books available locally, the internet and accessing articles from various scientific journals. Revenue is obtained from the number of purchases of vegetables or the amount of production multiplied by the number of sales of vegetable traders for one week. The results of the study show that the vegetable traders in the Pinasungkulan Karombasan Market, Wanea District, Manado City can be said to be profitable. The total profits obtained from 15 respondents amounted to IDR 23,949,845 with an average of IDR 1,596,656 for selling vegetables in one week. This income value is quite enough for one week's income, it is possible that it will increase if vegetable buyers increase, especially on holidays which require the local community to buy more vegetables.
Analisis Pendapatan Usahatani Jahe Di Desa Mokobang Kecamatan Modoinding Kabupaten Minahasa Selatan
Authors: Rorimpandey Lovenia Regina , Sondakh Mex Frans Lodwyk , Waney Nordy F.L.
Published: March 2023

This study aims to analyze the income of ginger farming in Mokobang Village, Modoinding District, South Minahasa Regency. The research was carried out for 2 months from July to August 2022. The sampling method used the purposive sampling method with criteria based on farmers who had harvested during the research, taken farmers who harvested the January-June period and the July-August 2022 period with 15 respondents. farmer. The research uses primary data obtained from direct observation and interviews with respondents using a questionnaire. Secondary data was obtained from related agencies, namely the Agricultural Extension Center (AEC) Modoinding District and the Mokobang Village Government. The analytical method used in this research is income analysis and farming feasibility analysis. The results showed that the average income of ginger farming which was harvested in January-June was IDR 2,515,636/Ha with an average land area of 0.61 Ha, while the income earned by ginger farmers who were harvested in July-August was IDR 3,714,610/ Ha with an average land area of 0.29 Ha for one growing season (9 months). The R/C ratio of ginger farmers who harvest in January-June is 1.10 and the R/C value of ginger farmers who harvest in July-August is 1.09. The R/C value obtained is more than 1, this shows that ginger farming in Mokobang Village is feasible to be cultivated.
Investigation on synthetic aperture imaging using focused transmit beams for cardiac ultrasonography
Authors: Sugioka Kotaro , Mozumi Michiya , Omura Masaaki , Nagaoka Ryo , Hasegawa Hideyuki
Published: March 2023

In the present study, we examined synthetic aperture imaging using a focused transmit beam. In this investigation, we evaluated the effects of the calculation of the transmit propagation delay time and transmit apodization. The transmit propagation delay time was calculated with the theoretical assumption of the transmitted wave and the propagation delay database created in advance by simulation of the transmitted beam. The results of simulation and phantom experiments showed that the bias error in the estimated motion velocity could be improved from −0.16 to −0.01 mm s−1 and the rms error from ±11.75 to ±8.97 mm s−1 without significant degradation of the spatial resolution at a frame rate about three times higher than that of the conventional method. Furthermore, in the in vivo data analysis, the proposed method depicted temporal changes in myocardial motion velocities within a cardiac cycle without aliasing.
IS LOW DOSE KETAMINE EFFECTIVE AS ANTIEMETIC PROPHYLAXIS FOR INTRAOPERATIVE NAUSEA AND VOMITING DURING CAESAREAN SECTION UNDER SPINAL ANAESTHESIA: A PROSPECTIVE RANDOMIZED STUDY
Authors: Puri Rahul , Situ Situ , S. Minhas H. , Rastogi Bhawana , Solanki Ankita , Niharika Niharika
Published: March 2023

Background: Intra-operative nausea and vomiting (IONV), which occurs in around 40- 60% of the
patients undergoing CS under regional anaesthesia, is an uncomfortable feeling for patients, upsets
obstetricians, distresses anaesthetists and may increases the risk of visceral injury during surgery because of the involuntary
uncontrolled abdominal movements. Hypotension can induce the emetic symptoms by leading to cerebral hypo perfusion.
Ketamine has unique central sympathomimetic, vagolytic and analgesic properties. These properties of ketamine are
assumed to reduce the incidence of spinal induced hypotension and consequently nausea and vomiting. Material and
methods: 120 patients posted for caesarean section under spinal anaesthesia were enrolled for the study after clearance from
institutional ethical committee. Patients of group I - received low dose IV ketamine in dose of 0.5 mg/kg in 5ml Normal Saline
Group II - received IV ondansetron in dose of 4 mg in 5ml Normal Saline Group III - Received IV 5ml Normal Saline, slow IV over
5 mins. Incidence of nausea, vomiting and complete response, hemodynamic, sedation score and block characteristics were
noted at xed intervals. Results: group I (ketamine) had maximum percentage of complete response (82.5 %). The difference in
complete response among the three groups was statistically signicant (p value – 0.001), whereas incidence of nausea and
vomiting among the three group was comparable (p value – 0.021, 0.037). Apgar score noted was of grade 9 with statistically
insignicant difference among all the groups (p- value 0.52). Conclusion: patients undergoing elective caesarian section
under spinal anaesthesia who have high risk of IONV; prophylactic therapy of low dose ketamine (0.5 mg/kg) just before giving
spinal anaesthesia can be used for prevention of IONV without any adverse effect on neonates similar to IV ondansetron.
EXPLORATION OF OVERWHELMING CRISIS OF PTSD THROUGH TRAUMA NARRATIVE OF ROXANE GAY'S AN UNTAMED STATE
Authors: Sivaranjini B. , Punitha S.
Published: March 2023

The 21st century is a tech world undergoing surplus uctuations, familiarizing the new era, literature
reects real life changes, challenges, problems and chaos. Though complications like famine,
pandemic, accidents, failures, physical abuses, wars etc., physically gets alright, mind and the repressed memory nds a way
out and the individual faces the psychological tremor, recollecting and re-living the traumatic moment that causes anxiety and
waves of panic. The main objective of this paper is to explore the overwhelming emotional crisis of an individual affected from
PTSD and the ruptured life after the traumatic incident through the interesting narrative of Roxane Gay's An Untamed State. The
plot revolves around the character Mireille, a lawyer abducted for a huge ransom undergoes severe physical and psychological
torture. The real horror of her life and unspeakable trauma explodes when she was released after 13 days. Her devastating
bitter experience starts to shake her life stripping her identity and affecting her remarkable life altogether. The novel and the
psychological study credibly portray and put forth the intricacies of rape trauma syndrome stricken life and surviving its erce
pangs
A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF CARBOXYMETHYLCELLULOSE AND POLYETHYLENE GLYCOL ARTIFICIAL TEARS ON SUBJECTIVE AND OBJECTIVE PARAMETERS OF DRY EYE DISEASE
Authors: Tyagi Akshat , K. Malik V. , Dhar Malvika
Published: March 2023

Purpose: To compare the changes in Ocular Surface Disease Index (OSDI) and Tear Film Break up Time
(TBUT) with carboxymethylcellulose and polyethylene glycol containing articial tears in patients of dry
eye disease (DED). Methods: This prospective randomized study consisted of patients above 18 years of age diagnosed as a
case of dry eye disease. The patients were equally divided into two groups; Group A & Group B. Participants in Group A were
prescribed carboxymethylcellulose (0.5%) containing articial tears while participants in Group B were prescribed
polyethylene glycol (0.4%) containing articial tears. OSDI and TBUT scores were recorded at baseline, at 1 week and then at 6
weeks. Results: OSDI and TBUT scores were comparable at baseline in both the groups. Group B had signicantly improved
OSDI and TBUT scores compared to Group A after 1 week and also after 6 weeks. Conclusion: Polyethylene glycol (0.4%)
articial tears are superior to Carboxymethylcellulose (0.5%) articial tears in improving OSDI as well as TBUT scores in DED
patients
A RARE CASE OF OESOPHAGEAL DUPLICATION CYST IN ADULT
Authors: Shukla Shivangi , Zaidi Noorin , Yadav Ankita , Lal Nirupma , Irfan Sumaiya
Published: March 2023

A Duplication cyst of the oesophagus is the 2nd most common congenital anomaly of the Gastrointestinal
tract. It has an estimated prevalence of 0.012% with a higher predominance in males, representing the 10-
15% of all gastrointestinal duplication defects. Although it is a common nding in children, diagnosis of an oesophageal
duplication in adults is rare. They are often asymptomatic but they may experience symptoms such as stridor or dysphagia
corresponding to the lesion within the neck or mediastinum or be complicated by intracystic haemorrhage, rupture & infections.
Here we present a case of an adult patient presenting with an oesophageal duplication cyst
A STUDY ON PATTERN AND CLINICAL PROFILES OF CONGENITAL HEART DISEASES IN TERTIARY CARE CENTRE, KAKINADA.
Authors: S. Raju M. , Satya Kumari K. , Anjana Gayatri B. , Hari Ramani B.
Published: March 2023

BACKGROUND: Congenital heart disease is an abnormality of anatomical structure of the heart that is of paramount importance. The incidence is approximately 8 per 1000 live births. CHD not only contributes to signicant mortality and morbidity but also causes tremendous psychological stress and economical burden to whole family. OBJECTIVE: To study the pattern and clinical prole of congenital heart diseases in a tertiary care hospital and to aid for early st detection and quick referral of children with congenital heart disease RESULTS: In this study, done between January 1 2020 to june 31st 2021, 54 children with conrmed congenital heart disease were observed. ACHD was the most common type of CHD and of them, VSD was the most common type, followed by ASD. Based on sex distribution, 31 were male (55.5%) and 23 were female (44.5%), with a male: female ratio of 1.25:1. Most children belonged in the age group 6m – 1year (46.2%) followed by (42.5%) in 30days – 6months age. The common clinical presentation observed in this study was breathlessness. The common complication observed in the current study was heart failure followed by malnourishment and recurrent LRTI.
EVALUATION OF INSULIN RESISTANCE AND LIPID PROFILE IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME
Authors: Bhardwaj Snigdha , Saini Vandana , R. Verma Archna
Published: March 2023

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive
age women. It is associated with dyslipidemia and Insulin resistance which is a high risk factor for
cardiovascular disease in the long-term. Objectives:Aim of study to determine Insulin Resistance, lipid prole, ApolipoproteinA1 and Apolipoprotein- B levels in women with polycystic ovary syndrome. Study Design: Hospital based observational case
control study. Method: We evaluated 80 polycystic ovary syndrome women as cases and age matched 80 women as controls
visited to obstetrics and gynaecology OPD at NDMC Medical College and Hindu Rao Hospital, Delhi, India. The case selection
was done according to Revised Rotterdam criteria (2003). Lipid parameters, Apo lipoprotein -A & Apo lipoprotein -B. Fasting
blood sugar and fasting Insulin were measured. Insulin resistance (IR) was calculated by the HOMA-IR formula. Results: The
present study showed signicantly higher values of triglycerides ( 48%) , HDL-C(46.95 ± 10.21mg% ) ,fasting glucose (25%)
and IR (10 %)in case than control (8%, 41.78 ± 9.71 mg% , 7% and 5% respectively) and signicantly low value of Apo
lipoprotein-A (45%) in PCOS women than controls (1.25%).Whereas the values of Total cholesterol, LDL-C, VLDL-C,
Apolipoprotein B, fasting insulin ,TC/HDL and LDL/HDL ratios was not signicantly different between two groups.
Conclusion: In the present study PCOS women had hypertriglyceridemia and raised IR whereas Apo lipoprotein -A was found
low. These parameters are considered as high risk factors for cardiovascular disease. Early and regular screening of PCOS
women can prevent progression of cardiovascular diseases.
RISING TRENDS IN ANTIBIOTIC RESISTANCE
Authors: Sreeja B. , Prathyusha Reddy P. , Ravinder Reddy K.
Published: March 2023

Antibiotics are medications that are used to prevent and
manage infections caused by bacteria. Antibiotic resistance
arises when bacteria mutate in response to antimicrobial
therapy
COMBINED EFFECT OF UPPER EXTREMITY PNF AND ELASTIC RESISTANCE BAND TRAINING ON INSPIRATORY MUSCLE STRENGTH IN CHRONIC KIDNEY DISEASE PATIENTS UNDERGOING HEMODIALYSIS.
Authors: Ramesh Bankar Sheetal , Kumar Das Arijit , D. Diwate Abhijit
Published: March 2023

Aim: The study aims to evaluate the effect of unilateral upper extremity proprioceptive neuromuscular
facilitation using an elastic resistance band on inspiratory muscle strength in chronic kidney disease
patients undergoing hemodialysis. 7 patients (4 male; 3 female) were assessed for demogr Materials and Methodology: aphic
data (age, weight, height, BMI) and Maximal Inspiratory Pressure (MIP) at baseline. All 7 patients underwent 8-week resistance
training for the unilateral upper extremity. The intervention used was unilateral upper extremity proprioceptive neuromuscular
facilitation (PNF) exercises combined with an elastic resistance band (ERB). Upper extremity PNF patterns (D1 exion,
extension & D2 exion, extension) were used in the training protocol. All the exercises were carried out on the dialysis bed
during an intradialytic period. 2 sessions per week for 8 weeks; a total of 16 sessions were held. 3 sets of 6 repetitions were given.
After completion of the training protocol, MIP was re-evaluated. In pre-and post-training comp Results: arison, there was
statistically signicant improvement (p < 0.0056) in the post-training Maximal Inspiratory Pressure (i.e., 62.71±27.85 cmH2O)
compared to pre-training maximal inspiratory pressure (i.e.,55.71±24.39 cmH2O). Intradialytic unilateral upper Conclusion:
extremity resistance training can improve the inspiratory muscle strength in chronic kidney disease patients undergoing
hemodialysis.
CRITICAL ANALYSIS OF MATERIAL BEHAVIOUR IN WELDED PLATES OF AISI 0.2%-C STEEL UNDER AS-WELDED, QUENCHED AND ANNEALED CONDITIONS
Authors: Dewangan Saurabh , Nemade Vedant Vinod , Nemade Kanad Harshal
Published: March 2023

AISI 1020 grade of steel is well known for its good combination of high strength and fair ductility. Therefore, it is widely demanded in construction sectors. It possesses a good weldability too in both arc and gas welding conditions. In the present work four pairs of AISI 1020-0.2%C steel plates were welded by shielded arc welding method. Except one welded plate, other three were heat treated. Based on the heat treating, three different physical conditions were achieved- water quenched, oil quenched and annealed. All the samples were tested for tensile strength, hardness, and microstructure. The annealed specimen has showed a significantly improved tensile strength of 439 MPa which is 85% higher than as-welded specimen. Water and oil quenched specimens showed lesser strength than that of as-welded specimen. With regard to hardness, there were two different observations. The as-welded and annealed specimens indicated the highest hardness at welded joint whereas the lower values were reported in base metal part. In contrary, the water and oil quenched specimens were harder in base metal zone as compared to welded zone. Both, strength, and hardness were found in good correlation with microstructural appearance of the plates.
Irrigation scheduling and soil moisture use on growth and yield of late sown wheat (Triticum aestivum L.) varieties
Authors: Gond Suraj , Singh M. K. , Satapathy S. M.
Published: March 2023

The present investigation was intended to determine the growth , yield capacity and soil moisture use of different late sown varieties of wheat (Triticum aestivum L.) under different irrigation schedules. is the present study was undertaken with an objective to evaluate the varietal performance under less moisture availability. To fulfil the aim the field experiment was conducted during winter (Rabi) season of 2019-20 with the combination of three irrigation schedules as main plot, and five late sown wheat varieties as sub plot factor, with three replication. Significant impact of three irrigations on crop growth, yield and total soil moisture use was observed over two and one irrigation schedule. Among varieties, WR-544 reported superior growth and yield attributes, where the grain yield was 11.5–15.0% more over MACS-6222, HS-562 and HD-3086, and was at par with HI-1544. Better establishment and tillering capacity of the varieties HI-1544 and WR-544 resulted in efficient moisture utilisation starting from CRI to harvest stage compared to the variety MACS-6222. Irrigation scheduling at the critical moisture stages resulted in efficient soil moisture use by the late-sown varieties HI-1544, WR-544, HS-562 and HD-3086.
Reflective mulch films a boon for enhancing crop production: A review
Authors: Deepika Yadav  , Ramana Rao KV  , Ayu Ayushi Trivedi , Yogesh Rajwade  , Neelendra Verma
Published: March 2023

Mulches are materials that are put to the surface of the soil for a variety of reasons. Plastic mulches of various colours have been developed and employed in a variety of agricultural production methods. Colored plastic mulches are used to modify the radiation budget and prevent soil water loss. It also helps with weed and insect infestation, as well as soil temperature regulation, water efficiency, plant development, yield, and quality. This paper reviews and discusses the understanding and prospective application of coloured plastic mulches to improve soil physical attributes growth, yield, and crop quality. Colored plastic mulches' effectiveness in minimising the detrimental impacts of environmental stress on crops is also explored. The impact of coloured plastic mulches on soil temperature has been documented by several researchers to vary from area to area and crop to crop. Various physicochemical mechanisms have also described that result in increased crop productivity when coloured plastic mulches are employed. Colored plastic mulches have a significant impact on soil temperature, moisture, and water holding capacity, according to the study. Clear and white plastics lower the temperature of the soil, but black and blue plastics raise it. A higher number of fruits, roots, tubers, and bulbs were produced when coloured plastic mulches were used. TSS, Vitamin C, and the proportion of liquid in diverse plants all improved significantly. Infestation of weeds and viral diseases has also been found to be significantly reduced. Reduced plant growth and yield, increased pest infestation, microplastic pollution, soil puddling, soil structural loss, and reduced soil-microorganism activity are some of the disadvantages of coloured plastic mulches. As a result, using coloured plastic mulches demands a detailed investigation of interactions with factors such as cropping season, root zone temperature, crop type, insect pest infestation, and water use efficiency.
OPTIMIZATION OF PYROLYSIS PARAMETERS IN PRODUCTION OF PYROLIGNEOUS ACID FROM ACACIA TWIGS
Authors: B. Doti  , D.M. Nyaanga  , S. Nyakach
Published: March 2023

Biomass material is a renewable energy source that is readily available and being produced in large quantities as most of it goes to waste. These materials can be recovered through pyrolysis process in order to produce usable products like biochar and pyroligneous acid. These products can be used as bio-fertilizer and bio-pesticides. The aim of this research was to optimize the pyrolysis parameters in the production of pyroligneous acid from acacia twigs. The parameters varied were feedstock moisture content (10%, 15% and 20%), Pyrolysis residence time (90 minutes, 135 minutes and 180 minutes) and chimney inclination angle (30o, 45o and 60o). Smoke condensation system also known as heat exchanger was used for condensing the pyrolysis smoke in to pyroligneous acid. Response Surface Methodology technique by using Box-Behnken Design was used to develop a mathematical equation to predict the yield of the pyroligneous acid with respect to varied parameters which was later optimized to determine the optimal conditions for pyroligneous acid yield.
ACCOUNTING, REGULATORY AND LEGAL ASPECTS OF CHARITABLE DONATIONS BY BUSINESS ENTITIES FOR THE ARMED FORCES OF UKRAINE
Authors: PODOLIANCHUK Olena , KOVAL Natalia , ISHCHENKO Yana
Published: March 2023

In the article, a study of the regulatory and legal support of the activities of charitable organizations and support by business entities of the Armed Forces of Ukraine is carried out. Problematic aspects of accounting and taxation of charitable assistance provided by business entities for the needs of the army are presented and the relevance of solving this methodological issue is substantiated. In particular, it is determined that different terms are used in legislation and scientific literature to describe charity. Forms and types of charitable activity in Ukraine were studied. Attempts have been made to distinguish between these concepts. The forms of charity (volunteer, humanitarian, philanthropic) are characterized and the types (charitable donation, charitable grants, public collection of charitable donations, charitable servitudes and charitable endowments) and methods of their giving are substantiated. The characteristic features of charitable assistance are determined: voluntary, selfless, purposeful. The need to regulate certain provisions and define terms in the field of charitable activities was confirmed, and amendments to the current legislation were proposed. The rating of charity in Ukraine was studied and the distribution of costs by spheres of its provision was presented. It was found that according to Ukrainian legislation, charitable assistance to the army is provided in the form of charitable donations and can be provided both in cash and in kind, in particular from charitable organizations, legal entities and individuals, and territorial communities. It has been proven that properly organized accounting of charitable donations will ensure the control of the intended use of the donated property and reduce abuses in this area, as well as affect the possibility of applying tax benefits in the terms of payment of value added tax, excise duty and income tax. The procedure for documenting charitable donations for the benefit of the army and the need to form an Act of acceptance and transfer of humanitarian (charitable) aid are substantiated. The changes made to the Tax Code of Ukraine regarding the taxation of charitable aid given to the army were considered. Taking into account the specifics of the research, a method of accounting for charitable assistance for various options for its provision (voluntary transfer or alienation of property) is proposed.
Acromegaly: The Impacts of HGH Release on Patient Progression
Authors: Slater Gordon
Published: March 2023

Hypersecretion of human Growth Hormone (hGH) is the primary mechanism driving Acromegaly, a disease characterised by abnormal growth of extremities and disfigured facial features. This article will discuss hGH secretion, its effect on Acromegaly, and potential treatments for the disease, among other key topics.
The Effect of Stem Cells on Meniscus Tear Injuries
Authors: Gallicchio Vincent S
Published: March 2023

The Meniscus injuries are associated with pain, swelling, impairment in function and activity levels as well as early osteoarthritis of the knee joint. The prevalence of meniscal tear injuries is close to 12% to 14%, with an occurrence of 60-70 cases per 100,000 individuals. There are about 850,000 cases per year and the global annual cost is estimated at $4 billion. Professional and amateur athletes demonstrate meniscus tear rates between 1.58-2.98 injuries per 10,000 athletic exposures. Sports with the highest rates of athletes affected by meniscus tear injuries include: football, soccer, basketball, wrestling, and rugby. Meniscus tear surgeries may lead to potential side effects or medical complications. The effectiveness of stem cells for meniscus injuries in animal and human subjects is something that researchers have investigated. Often preferred mesenchymal stem cells are the source for procedures seen in orthopedics as they change into many types of tissues including: cartilage, bone, muscle, bone, and fat. The use of stem cells in transplantation has shown an improved rate of healing, enhanced tissue quality, sustained functional gains, and improved outcomes in clinic. Researchers think the use of stem cells may offer other options for people with an orthopedic injury including meniscus tears decreasing recovery time, improving function, and decreasing degenerative osteoarthritis.
Study of the Antiviral Activity and Toxicity of Dextrin - In Vitro Study
Authors: Hakobyan Gagik
Published: March 2023

Objective: This study was to in vitro study of the antiviral effect of "Dextrin" on the replication of the EMCV virus in HeLa cells and toxicity of "Dextrin". Methods: For this purpose, the virus at a dose of 100 TCD50 is applied to a 24-hour monolayer of HeLa cells. The experiment is carried out under conditions of 5% CO2 saturation and 100% humidity. The virus dose used was expressed as a tissue cytopathic dose of 100 TCD50/ml. Cultivation of HeLa cells, to study toxicity, was performed on 96-well plates under conditions of 5% CO2 saturation and 100% humidity. The toxic effect of "Dextrin" on HeLa cells was studied by the degree of destruction of the monolayer and at the population level. Results: Peak levels of the virus reached after 48 hours of replication accompanied by complete destruction of the cell monolayer (7-8 cycles of replication). As follows from the graph, “Dextrin significantly” (significance is indicated by asterisks.) reduces the dose of the virus when introduced into the medium with HeLa cells to, or at the early stages of EMCV virus replication (-1,0 and 1 hour). Based on the data obtained, it was decided to use a dose of 1:100 (1%), which is the highest non-toxic dose. Conclusion: “The investigated Dextrin has an antiviral effect against the EMCV virus, when applied in the early stages of infection. This may open up the prospect of studying the antiviral spectrum of Dextrin in more future studies”.
The Herculean Task of Tedros
Authors: Maes Roland
Published: March 2023

The WHO was created in 1950 with the prime assignment to fight tuberculosis. To this end, it was granted immunity against any prosecution. The French state immediately exploited this advantage to impose the BCG vaccine developed by the Pasteur institute, although this vaccine was known, by both the Pasteur institute and the WHO, to be deficient. It was poorly attenuated and some of its strains favor the spread of TB. The BCG also favors the spread of leprosy. The WHO knew this and nevertheless supported this fraud. It banned serological tests and imposed an expensive antigen- detection test, the Xpert/Rif test, in 2011. This test was rapidly demonstrated to be peppered with severe deficiencies, which were ignored by the treatment action group (TAG) and the WHO. Both insisted on its use while systematically denigrating the serological tests that this antigen-test was supposed to replace. The result of the use of this ill-functioning test was the spread of multi-drug resistant strains of TB. Serological tests monitor the immune status of infected patients: it allows the detection of those patients prone to convert as well as the immune status of patients under therapy. Those who do not respond to current treatment are therewith detected. A shameful demand of financial contribution by those countries that suffered most from the mismanagement of TB by well–endowed nations is currently underway.