bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of lifestyle habits on the evolution of arterial hypertension in adults
Authors: Nazate Chuga Zuly Rivel , Pozo Hernández Clara Elisa , Meneses Ponce Santiago Cristopher
Published: June 2024

At the Nueva San Rafael Health Center in Esmeraldas, a study was carried out with adults between 35 and 60 years old to evaluate the influence of lifestyle habits on the evolution of high blood pressure. The study used questionnaires and direct observations to collect data and evaluate patients' high blood pressure behaviors through direct observation. The research identified that family history, poor health habits and being overweight were the main risk factors. The findings confirmed the need for early and personalized interventions, especially in populations at high genetic risk. The educational strategies applied were effective in promoting healthy habits and reducing risk factors, which suggests that they can be replicated in other public health programs. Together, a proactive and evidence-based approach was proposed to improve both individual and community interventions. In addition, the need to investigate more about the sustainability and long-term impact of these educational strategies and the contribution to future public policies was identified. It has been concluded that early intervention in the evolution of high blood pressure and the promotion of continuing education is necessary to mitigate risk factors. Therefore, it has become necessary to promote healthy lifestyles, and, consequently, improve the quality of life of adults affected by this prevalent medical condition
Leadership and organizational commitment in public universities of tungurahua province - republic of ecuador
Authors: Bejarano Lizano Byron Omar , Guamán Guevara María Dolores , Monserrath Monge Moreno Adriana , Ramos-Ramírez Martha Cecilia
Published: June 2024

Introduction: Leadership in organizations is continuously studied, always in search of new models that can adapt to organizational processes with greater flexibility, a reality that obliges organizations to adapt to avant-garde styles to promote organizational commitment.Objective: To explain the relationship between leadership and organizational commitment in public universities of the provincial government of Tungurahua - Republic of Ecuador.Methods: It is an explanatory research, embedded in the positivist paradigm, with a quantitative approach. The research design is field-based, transactional, and non-experimental. As a technique for gathering information, a Likert scale questionnaire was designed, with two parts for estimating leadership styles and organizational commitment, comprising a total of 80 items. The same instrument was validated through expert judgment, applied in a pilot test to 20 subjects with characteristics similar to the study population, obtaining reliability through Cronbach's alpha of 0.910. The collected information underwent processing and analysis through descriptive and inferential statistical methods. The results showed a moderate presence of laissez-faire leadership styles with a mean of 2.76 and democratic leadership with a mean of 2.11.Results: Regarding organizational commitment, there was a slight estimation with a mean of 1.93; within the analysis, a high correlation of (0.635**) was obtained, highlighting transformational leadership and organizational commitment.Conclusions: The factors of leadership influencing organizational commitment in public universities of the province of Tungurahua - Republic of Ecuador were determined. In this sense, it was determined that leadership style influences commitment within the organization with a strong correlation.It was established that promoting this type of leadership should continue through managerial guidelines that strengthen organizational commitment.
A systematic review of models for the prediction of corporate insolvency
Authors: Sathyanarayana N. , Narayanan Raja
Published: June 2024

A thorough evaluation of recent developments in bankruptcy prediction models developed specifically for listed firms in India is presented in this research. Beginning with influential contributions from the evolution of bankruptcy prediction methodologies is traced through various statistical techniques, including logistic regression, neural networks and discriminant analysis. Recent innovations, such as duration models, partial least squares with support vector machines, and efficiency-driven distress prediction, are discussed in the context of their applicability to the Indian market. The paper highlights the significance of early warning systems in the wake of bankruptcy reforms in India and examines the regulatory framework's impact on bankruptcy prediction modeling. And it goes further into how macroeconomic variables and industry-specific variables might make bankruptcy models better predictors. Limitations such as small sample sizes, short time periods for samples, and the incorporation of qualitative data into predictive models are highlighted in the study as areas that require further investigation in future studies. Overall, this paper provides valuable insights for academics, practitioners, and policymakers involved in bankruptcy prediction and risk management within the Indian corporate sector
STUDY OF THE PHARMACOKINETIC PROPERTIES OF A SPECIAL FORM OF VITAMIN D IN A RAT MODEL (IN VIVO)
Authors:   Autonomous non-profit organization «International association of clinical pharmacologists and pharmacists», Moscow, Russia, Kukes I.V , Pozdnyakov D.I ,   Pyatigorsk Medical and Pharmaceutical Institute
Published: June 2024

Vitamin D is a key factor in maintaining musculoskeletal health as it helps absorb calcium and phosphorus, which are necessary for the formation and strengthening of bone tissue. However, the role of vitamin D is not limited to this. Research has shown that vitamin D also plays an important role in the functioning of the immune system, regulating inflammation, and reducing the risk of developing cardiovascular diseases, diabetes, autoimmune diseases and cancer. Modern pharmaceutical technologies strive to develop vitamin D3 delivery systems that are not only more resistant to oxidative or photolytic degradation during shelf life, but are also better absorbed and have higher bioavailability. One such technology is the use of colloids. A colloid is typically a two-phase system consisting of continuous and dispersed phases. The dispersed phase particle size is typically between 0,001 and 1 micrometer. Most colloidal products are formulated to remain stable for a certain shelf life. These suspensions can be formulated in such a way that the particles remain suspended without settling to the bottom. With this approach, vitamin D3 can be more stable and bioavailable, as well as more effective.
RENDIMIENTO Y CALIDAD FÍSICA DEL GRANO DE CAFÉ (Coffea arabica L.) VARIEDAD COSTA RICA 95
Authors: De Dios-León Gloria Esperanza , Angel-Lara María Alva , Osorio-Hernández Paola , Coria-Gil Norma Ana Beli
Published: June 2024

Background: Coffee is the second most consumed drink in the world, only after water. Quality characteristics are the most recurrent demands of consumers, which are of multifactorial origin and among which is agronomic management where soil nutrition or foliar nutrition of the plant is considered. Objective: To evaluate the yield and physical quality of the bean and cup of coffee (Coffea arabica L.) variety Costa Rica 95 by applying foliar fertilizer. Methodology: The evaluation was carried out in the La Laja community, municipality of Tlaltetela, Veracruz between 2018 and 2019. The age of the plantation used was four years and established with chalahuite shade (Inga spuria Humb. & Bonpl. ex Willd). The design used was a complete randomized block with two treatments (commercial control and treatment with foliar fertilization), with three repetitions each; the experimental unit consisted of a 300 m2 plot and five coffee harvests were carried out, which were according to the number of flowerings during the 2018-2019 cycle. The physical evaluation was carried out according to the Official Mexican Standard NMX-F-162-SCFI-2008 and the NOM SCAA (2013).  Results: The highest cherry yield and brix degrees were observed in the fertilized treatment with 12,897.8 kg ha-1 and 20.06, respectively; in floats (waste) and snail (malformation), the highest weights were observed in the control treatment with 1,696.11 kg ha-1 and 21.4 grams, respectively. The total sum of the sensory analysis was 81.3 and 85.2 for the treatments: control and fertilized, respectively. Higher numbers of grains were observed in sieves 19, 18 and 17 that are classified for the international scale. Implications: There is a positive effect of foliar fertilizer on the yield of cherry coffee and cup quality of Costa Rica coffee 95 and opens a range of possibilities to carry out a greater number of fertilization tests in the field, being able to compare an additional factor such as, for example, the climate (rain, drought, cold, heat, etc.). These studies should be carried out in the same area in which this experiment was carried out to compare whether the response shown is due solely to foliar fertilizer or there is an influence of climate, as well as management. It must be considered that the quality of coffee is multifactorial; in addition to environmental and genetic factors, there is management (nutrition, phytosanitary protection, pruning), harvest, among others. Conclusion: Foliar fertilization considerably improved the variables of interest evaluated in Costa Rica 95 coffee through the application of foliar fertilization, in addition to the fact that no primary or secondary defects were significantly present.
NANOPARTÍCULAS METÁLICAS POR SÍNTESIS VERDE Y SU APLICACIÓN COMO INSECTICIDAS
Authors: Zavala-Zapata Vidal , Aguirre-Uribe Luis Alberto , Ramírez-Barrón Sonia Noemí , Hernández-Juárez Agustín
Published: June 2024

Background: The synthesis of nanoparticles from living organisms better known as biological synthesis or green synthesis has become a potential tool due to the advantages it provides compared to other existing synthesis methods. Green synthesis is presented as an environmentally friendly, safe, less toxic and cost-effective alternative. Due to these properties green nanoparticles have been implemented in the field of agriculture, mainly as nanopesticides. Objective: To review the reports on the evaluation of green nanoparticles against insects, as well as the knowledge on the possible modes of action of these nanoparticles. Methodology: A compilation of scientific information was made in different search engines, from which those that evaluated nanoparticles by green synthesis as insecticides were selected. Results: Among the modes of action caused by metallic nanoparticles, the following stand out: damage and histological changes at intestinal level, antifeedant activity, physical damage to the cuticle, decreased cell viability and inhibition of fecundity. Implications: the availability of information on nanoparticles is fundamental to be able to scientifically propose their implementation in insect pest management strategies. Conclusion: green synthesis of nanoparticles is presented as an alternative to produce nanoinsecticides; however, further research is needed on the mechanisms of action on insects, as well as their long-term repercussions on human and environmental health.
PERCEPCIÓN DE PEQUEÑOS PRODUCTORES RESPECTO A LOS EFECTOS DEL CAMBIO CLIMÁTICO EN LA FLORACIÓN Y PLAGAS DE AGROECOSISTEMAS CAFETALEROS: UN ESTUDIO DE CASO
Authors: Beristain-Moreno Martha Escarlet , Ramírez-Martínez Alejandra , Sósol-Reyes David , Osorio-Acosta Francisco
Published: June 2024

Background. The coffee production in Veracruz state is important in the economic, social, cultural, and environmental sectors, mainly for the small producers who are dedicated to this activity. However, this sector has different problems that have generated its stagnation or abandonment, some of these are caused by the effects of climate change, coupled with the inadequate management of coffee agroecosystems that favor deforestation, low biodiversity and the elimination of natural enemies of pest organisms. Objective. To assess the perception of small coffee producers about the relationship among flowering, pests and climate change in Sabanas, Veracruz. Methodology. Eleven producers were interviewed through a questionnaire with open questions that allowed them to state how they perceive coffee flowering, pest problems, climate change and how they relate to each other. Results.  The main problems they mentioned are pests, drought, and delayed flowering. The main pests they mention are rust, nematodes, and the berry borer, and they also indicate the presence of the coffee stem borer, which they had not previously observed. Finally, they perceive that herbicides, deforestation and pollution negatively affect their agroecosystems. Implications. The work suggests carrying out monitoring in the study area and/or surrounding areas to know the dynamics and distribution of the pests present in the crop. Conclusion. Small producers relate the increase in severity and the occurrence of new pests with climate change. In addition, they observe that changes in temperature and precipitation influence the delay in flowering and generate certain stress in the plantations, which they consider it is aggravated by practices such as the application of herbicides and the removal of shade trees.
PEMILIKAN MAKNA, TUJUAN DAN NILAI KEHIDUPAN DALAM KALANGAN PELAJAR UNIVERSITI DI MALAYSIA
Authors:   Universiti Putra Malaysia, AB RAZAK RATNA ROSHIDA
Published: June 2024

ABSTRAK Kehidupan yang mempunyai makna, tujuan dan nilai telah menjadi tumpuan utama beberapa teori dalam psikologi kemanusiaan. Hal ini dikira penting kerana dengan memiliki tiga perkara asas ini seseorang individu dapat mengoptimunkan kehidupannya. Pengukuran makna hidup agak sukar untuk dilakukan kerana halangan yang bersifat kebimbangan pragmatik seperti mengukur pengalaman yang bersifat subjektif dan ketidaksesuaian teori atau pendekatan yang ada diperkenalkan oleh ahli psikologi kemanusiaan. Walau bagaimanpun Logoterapi, sebuah pendekataan psikologi kemanusiaan dianggap sesuai untuk melihat persoalan makna, tujuan dan nilai hidup. Artikel ini bertujuan untuk mengetengahkan kaedah empirikal yang berkaitan dengan pemilikan makna, tujuan dan nilai melalui paradigma humanistik-eksistensi. Untuk tujuan ini, ujian makna logotherapeutic iaitu Mencari Matlamat Noetik (SONG) akan digunakan. Struktur faktor 20-item yang terdapat dalam ujian ini diaplikasikan melalui kaedah pengesahan analisis faktor (factor analytic). Kajian ini menggunakan data yang diperolehi daripada pelajar universiti awam Malaysia (N = 2056) Analisis faktor menyokong model dua faktor yang terdapat pada SONG. Corak korelasi yang terdapat pada dua factor ini iaitu Faktor 1, yang berkaitan dengan kehidupan yang menggembirakan dan memuaskan, memperlihatkan hubungan yang sangat kuat dengan Faktor 2 , iaitu tujuan dalam kehidupan. Kata Kunci: Makna, Tujuan Nilai, Pelajar Universiti
PENGARUH GAYA PEMANTAUAN MEDIA IBU BAPA MUDA TERHADAP TINGKAH LAKU AGRESIF KANAK-KANAK YANG TERDEDAH DENGAN GAJET
Authors:   Universiti Kebangsaan Malaysia, HAIZAN MAHBOB MAIZATUL
Published: June 2024

ABSTRAK Bagi menganalisis pengaruh gaya pemantauan media ibu bapa muda terhadap tingkah laku agresif kanak-kanak yang terdedah dengan gajet, kajian ini menggariskan empat objektif iaitu pertama, mengenal pasti hubungan antara pemantauan media ibu bapa dengan tingkah laku agresif kanak- kanak, kedua, menganalisis pengaruh pemantauan media terhad ke atas tingkah laku agresif kanak- kanak, ketiga, menguji pengaruh pemantauan media aktif ke atas tingkah laku agresif kanak-kanak dan keempat, menilai pengaruh pemantauan media penggunaan bersama ke atas tingkah laku agresif kanak-kanak. Bagi mencapai kesemua objektif, kaedah survei telah dijalankan ke atas ibu bapa muda yang mempunyai anak berumur tiga hingga enam tahun. Hasil kajian mendapati terdapat hubungan negatif yang signifikan antara pemantauan media ibu bapa dengan tingkah laku agresif kanak-kanak yang terdedah dengan gajet. Pemantauan media terhad pula menunjukkan pengaruh yang signifikan terhadap tingkah laku agresif kanak-kanak, manakala pemantauan media aktif dan penggunaan bersama tidak mempengaruhi tingkah laku agresif yang dikaji. Implikasi kajian kepada teori ialah pemantauan media ibu bapa masih signifikan dalam mengawal penggunaan gajet dalam kalangan kanak-kanak, manakala implikasi kajian terhadap ibu bapa ialah perlunya pemantauan penggunaan gajet terhadap anak-anak dengan menggunakan pendekatan pemantauan media terhad. Kata Kunci: Pemantauan Media Ibu Bapa Muda, Pemantauan Media Terhad, Pemantauan Media Aktif, Pemantauan Media Penggunaan Bersama, Identiti Kendiri
An Efficacy and Safety Comparison of Regorafenib and Nivolumab in Unresectable Hepatocellular Cancer Patients: A Systematic Review
Authors: Darmadi Darmadi , Sungkar Taufik , Pakpahan Cennikon , Surja Sem Samuel
Published: June 2024

Objective. This systematic review aimed to compare the efficacy and safety of regorafenib and nivolumab, two FDA-approved second-line treatments for unresectable Hepatocellular Carcinoma (HCC).
Methods. Literature comparing the efficacy and safety of regorafenib and nivolumab in unresectable HCC patients was systematically searched across seven databases, including: PubMed, SCOPUS, Cochrane Database of Systematic Reviews, ScienceDirect, EBSCOhost, EMBASE, and ProQuest, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. The search was done on April 2nd, 2023. Study quality and risk of bias were assessed using the Agency for Healthcare Research and Quality (AHRQ) and ROBINS-1 tools. The selected studies were included in the qualitative data synthesis.
Results. Three trials found that HCC patients taking nivolumab had statistically insignificantly longer OS, TTP, and progression-free survival than those on regorafenib. Nivolumab increased ORR, with largely partial responses, and mixed DCR, with little statistical significance. All three studies showed that nivolumab had fewer side effects and improved tolerance.
Discussion. Three retrospective cohort studies with a total of 383 regorafenib-receiving cohorts and 230 nivolumab-receiving cohorts were included in the qualitative analysis. Nivolumab was found to be superior in regards of longer overall survival, longer time to progression, higher objective response rate, and lower adverse event occurrence. However, statistical significance was not achieved in most of the parameters.
Conclusions. The use of nivolumab is preferable as the second-line systemic therapy for unresectable HCC. More high-quality studies are urgently needed to generate quantitative analysis, and to encourage the formation of guidelines for second-line systemic therapy.
Pelatihan Kewirausahaan Digital Untuk Atlet Kota Semarang
Authors: Natalia Sari Pujiastuti  , Julianto Edi Nurwahyu , Saptiono Ami
Published: June 2024

This service activity aims to increase the potential of athletes in the world of digital entrepreneurship for athletes assisted by KONI Semarang City through entrepreneurship training in the digital field. The potential for digital businesses in Indonesia is very large and is expected to continue to grow. Therefore the main focus of this activity is to provide a better understanding of the potential outside the world of sport as well as the digital entrepreneurial skills needed to start and manage your own business. The service method is in the form of understanding the Entrepreneurial Mindset, Facilitating Business Logo Creation and Digital Entrepreneurship Skills. By involving expertise in entrepreneurship and training, this program is designed to empower athletes to create independent economic opportunities. Through this approach, it is hoped that athletes can overcome economic challenges after retiring from their sports careers and create a brighter future as successful digital entrepreneurs.
ANÁLISE DA TRAJETÓRIA HISTÓRICA E LEGAL DA EDUCAÇÃO DE ALUNOS COM ALTAS HABILIDADES/SUPERDOTAÇÃO- AH/SD
Authors: Campelo Almervanda de Souza , Soares Helciyane do Firmamento Silva , Lima Márcia Raika e Silva
Published: June 2024

Pessoas com superdotação apresentam potencial elevado nas diferentes áreas do conhecimento em comparação à população. As políticas públicas, no Brasil, voltadas às altas habilidades/superdotação (AHSD) ocorrem há cerca de um século, considerando as primeiras publicações. Porém, somente na LDB 5692/71, oficialmente, em âmbito nacional, menção a esses alunos. Buscando resposta ao questionamento:  em quais leis, decretos e iniciativas, que tratam da Educação Especial no Brasil, a partir da atual LDB (9394/96), são garantidas políticas públicas aos AH/SD?  E com o objetivo geral de analisar a legislação educacional brasileira, a partir da atual LDB (9394/96) no que tange às políticas públicas de atendimento aos alunos com AH/SD, o texto faz uma cronologia partindo da Lei de Diretrizes e Bases (LDB 9394/96) perpassando por normativas e iniciativas públicas e privadas que trouxeram e trazem contribuições ao atendimento a esse público até o ano de 2023, com a promulgação do Parecer CNE/CP Nº: 51/2023 que especifica os passos do atendimento a alunos com AH/SD. A pesquisa documental, com abordagem qualitativa concluiu que há, no Brasil, leis e documentos norteadores, que fazem referências à garantia de atendimento a alunos AH/SD, porém os números de matrículas, no Censo Escolar, mostram a não efetivação dessas normativas.
BREVE PANORAMA SOCIOECONÔMICO DA RECICLAGEM NO BRASIL ATUAL (2024)
Authors: Cruz Uilmer Rodrigues Xavier da , Ferreira Eduardo Rodrigues , Garcia Ricardo Alexandrino
Published: June 2024

Este artigo aborda a gestão de resíduos sólidos no Brasil, explorando desafios e perspectivas alinhadas com o desenvolvimento sustentável. O problema de pesquisa reside na análise da eficácia das políticas públicas em lidar com essa questão e na investigação da correlação entre o crescimento econômico e a geração de resíduos. Assim, o objetivo principal é oferecer uma visão ampla e abrangente dessa problemática, examinando dados socioeconômicos e ambientais. Para isso, adotamos uma metodologia que envolve a análise de indicadores econômicos e sociais, além da utilização de equações para prever a quantidade de resíduos coletados. No que tange ao referencial teórico, abrangemos conceitos fundamentais de desenvolvimento sustentável, gestão de resíduos e políticas públicas. Dentre os resultados encontrados, destaca-se a necessidade premente de conscientização ambiental e a urgência de políticas integradas para promover uma gestão de resíduos sólidos mais sustentável e eficaz.
A Tribute to Helen Leith (28 February 1958 – 30 December 2014)
Authors: Atkinson Jessica , Cave Phoene , McDermott Orii , Odell Miller Helen , Pavlicevic Mercédès , Quin Alexia , Ridder Hanne Mette
Published: June 2024

Tribute to Helen Leith (28 February 1958 – 30 December 2014)
Bibliometric Analysis of Scientific Research on Children’s Disability in Saudi Arabia
Authors: Alghadier Mshari , Albesher Reem , Basoudan Reem
Published: June 2024

The study of children’s disability has gained significant attention worldwide due to its impact on individuals, families, and societies. As a rapidly developing country, Saudi Arabia has also witnessed an increased interest in understanding and addressing children’s disability. This review paper aims to conduct a comprehensive bibliometric analysis of the scientific research focused on children’s disability in Saudi Arabia. The analysis aims to identify the publication trends, research topics, influential authors, and critical collaborations within this domain. A systematic literature search was performed using electronic databases, including PubMed, Scopus, and Web of Science. The search terms used were related to children’s disability and Saudi Arabia. The inclusion criteria encompassed peer-reviewed articles published between 2000 and 2022, written in English, and focusing on children’s disability research in Saudi Arabia. The retrieved articles were analyzed using bibliometric techniques, including co-authorship analysis, journal analysis, and keyword analysis. The bibliometric analysis revealed a growing interest in children’s disability research in Saudi Arabia over the past two decades. A total of 1050 articles met the inclusion criteria and were included in the analysis. The analysis showed an increasing number of publications over time, indicating the expanding focus on this research topic. The key research areas identified included assessing and diagnosing disabilities, interventions and therapies, educational support, and social inclusion of children with disabilities. The analysis also identified prominent researchers and institutions contributing to this field. The bibliometric analysis provides a comprehensive overview of the scientific research landscape on children’s disability in Saudi Arabia. It highlights the increasing attention and research efforts in this area. The findings emphasize the importance of continued research in understanding the challenges faced by children with disabilities and developing effective interventions and support systems.
НОВЫЙ ПОДХОД К ЛЕЧЕНИЮ ДЕТЕЙ С АНОМАЛИЯМИ РЕФРАКЦИИ
Authors: Ф.А. Султонова
Published: June 2024

Актуальность. Как упомянул М. И. Авербах, «рефракционная офтальмология требует большего служения населению в количественном отношении, чем другие разделы офтальмологии». Цель исследования: совершенствование лечения детей с аномалиями рефракции. Материал и методы: в исследование были включены 220 глаза (110 больных) с аномалиями рефракций и 44 глаза (22 детей) с эмметропической рефракцией. Всем больным проведено визиометрия, рефрактометрия, биомикроскопия, офтальмоскопия, периметрия, УЗИ глазного яблока. Результаты: микротоковая рефлексотерапия дает высокий результат на функциональное состояние органа зрения. Заключение: микротоковая рефлексотерапия при всех видах амметропии оказывал нейропротекторное и ангиопротекторное действие.
РАЗВИТИЕ ГЛАУКОМНОЙ ОПТИЧЕСКОЙ НЕЙРОПАТИИ ПРИ ГЛАУКОМЕ – ВСЕГДА ЛИ АПОПТОЗ ГАНГЛИОЗНЫХ КЛЕТОК СЕТЧАТКИ?
Authors: Е.А. Егоров , А.М. Набиев , У.Б. Захидов
Published: June 2024

Актуальность. Термин «глаукома» включает значительную группу болезней глаза, объядиненных общим глаукоматозным синдромом. Повышение уровня внутриглазного давления и оптическая нейропатия в следствие которой проявляется атрофия зрительного нерва с ее экскавацией ведет к ухудшению и в поздних случаях потери зрительных функций глаза пациента. Необходимо отметить, что при офтальмогипертензии и глаукоме нормального давления оптическая нейрапатия является в качестве единственного деноменатора для всех форм глаукомного процесса. Цель исследования. Изучение возможной другой альтернативной апоптозной формы клеточной гибели при первичной глаукоме. Материалы и методы. Изучены научные работы, посвещенные роли апоптоза в развитии глаукомной оптической нейропатии, основанные экспериментальными и клиническими исследованиями. Результаты и заключение. Изучены и приведены факторы, воздействующие на гибель ганглиозной клетки сетчатки, которые могут являться первоначальной причиной запуска механизма апоптоза. Основываясь на проведенных работах установлены паталогоанатомические аспекты развития апоптоза. Установлено, что при глаукомном процессе запрограммированная гибель ганглиозных клеток сетчатки (ГКС) ускоряются вдвое, сравнительно потерь, связанных с возрастом пациента. Проведенный анализ будет способствовать разработке подходов к профилактике оптической нейропатии и ее прогрессирования еще на начальных стадиях глаукомного процесса.
ОПЫТ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ПОСТТРАВМАТИЧЕСКИХ ДЕФЕКТОВ И ДЕФОРМАЦИЙ КРАНИОФАЦИАЛЬНОЙ ОБЛАСТИ С ИСПОЛЬЗОВАНИЕМ ПРЕДОПЕРАЦИОННОГО ПЛАНИРОВАНИЯ И АДДИТИВНЫХ ТЕХНОЛОГИЙ (КЛИНИЧЕСКИЙ СЛУЧАЙ)
Authors: О.Н. Дудич , В.Л. Красильникова , В.С. Осипович , И.И. Малиновская , М.М. Салех
Published: June 2024

Актуальность. Актуальной задачей современной офтальмологии, челюстно-лицевой хирургии и нейрохирургии является повышение эффективности и качества хирургической помощи пациентам с посттравматическими дефектами и деформациями глазницы. Цель исследования. На клиническом примере продемонстрировать возможности разработанного программного средства на основе нейронной сети с использованием выходных данных МСКТв формате DICOM в реконструктивной хирургии краниофациальной области. Материалы и методы. В представленном материале описывается клинический случай пациента с последствиями сочетанной черепно-челюстно-лицевой травмы. Обследование включало визометрию, биомикроскопию, статическую автоматическую периметрию на этапах наблюдения. МСКТ черепа выполнялось до операции и непосредственно после реконструкции глазницы. Для анализа распространённости травматического процесса в глазнице, моделирования индивидуального имплантата использовалось разработанное программное средство на основе нейронной сети с использованием выходных данных МСКТ в формате DICOM. Результаты и заключение. Применение разработанного программного средства на этапе предоперационного планирования позволяет оценить распространённость травматического процесса в глазнице, создать виртуальную трехмерную модель поврежденной глазницы с зоной дефекта, определить последовательность этапов одномоментного реконструктивно-восстановительного лечения при краниофациальной травме, смоделировать персонализированный имплантат. Применение аддитивных технологий позволяет хирургу получить тактильную трехмерную модель поврежденной зоны лицевого скелета и изготовить персонализированный имплантат, что значительно повышает качество хирургического лечения данной категории пациентов.
ELEMENTerial – Construction System Study for CLT Offcuts
Authors: Tuksam Siim , Pihlak Sille
Published: June 2024

The ELEMENTerial research project focuses on the development of an innovative design and construction system for Cross-Laminated Timber (CLT) offcuts. CLT construction, while offering advantages for automation, raises concerns about offcut waste, which constitute 5-10% of the material production in Estonian CLT timber industry. This research highlights the importance of aligning timber construction with circular economy principles by effectively utilising offcuts. The study focuses on the development of a design method, creating a versatile and holistic construction system that breaks away from traditional orthogonal designs. Algorithmic tools are employed to streamline the design process and to help manage the complexities of working with smaller elements. The outcomes include a geometric strategy, offering variable configurations for assembly in walls, floors, ceilings and openings. The research demonstrates the potential to automate and pre-rationalise the design process, providing design freedom beyond orthogonal constraints and shell structures. The applications range from shelters to facade systems, building extensions to potentially large-scale construction systems. This study offers environmental benefits and design flexibility in the construction industry. It holds a potential to guide the sector towards reduced waste and increased material efficiency, fostering sustainability and economic value from waste materials. The prospects for future research include further automation, refinement of connection details, and efficiency in production and material usage.
Moisture Safety in Prefabricated Roof Renovations: Causes and Strategies
Authors: Kodi Georg-Mihkel , Kalbe Kristo , Kalamees Targo
Published: June 2024

Achieving carbon neutrality by 2050 requires extensive energy renovation of the existing building stock. In this study we focus on deep renovation with prefabricated insulation elements as a potential solution to attain the required renovation speed and volume. The use of such elements without a proper moisture safety strategy can, however, lead to moisture-related problems, including mould growth. Here we examine the causes of moisture and mould damage in a case study of a building that has been renovated to near-zero energy standards using prefabricated insulation elements.
The study elucidates the reasons for the moisture damages detected and proposes two moisture safety strategies to improve the situation. The first strategy emphasizes the importance of ensuring dry construction conditions by either using a full temporary roof or avoiding rainfall during installation. The second strategy addresses localized water damage to the attic floor and involves the use of protective measures, active ventilation and a correct installation sequence. In the case of local moisture damage, the required amount of ventilation air flow during summer is 0.5–0.55 l/(s·m²). During cooler periods, heating is needed.
The employed methods include modelling the case-study building with the IDA Indoor Climate and Energy software, as well as mould growth risk assessment based on temperature and relative humidity measurements. The results highlight the effectiveness of both strategies in preventing mould growth if applied correctly, and emphasize the need for thorough planning, moisture safety regulations and rapid response to ensure successful renovation with prefabricated insulation units.
The study provides valuable information on moisture safety strategies for serial renovations with prefabricated elements. The existence and proper implementation of a moisture safety strategy is important for achieving the desired energy performance goals while maintaining building durability and occupant health, and it needs to be applied throughout the chain of site management: from the main contractor down to the skilled worker.
Gesamtplanung in der Eingliederungshilfe – quo vadis?
Authors: Rohrmann Albrecht
Published: June 2024

Die Regelungen zur Gesamtplanung in der Eingliederungshilfe (§§ 117 ff. SGB IX) dürften zu den weitreichendsten Änderungen zählen, die durch das Bundesteilhabegesetz vorgenommen wurden. Der Implementationsprozess gestaltet sich schwierig. Albrecht Rohrmann erörtert ausgehend von der Entwicklung der Gesamtplanung in der Eingliederungshilfe einige grundlegende Fragen der Umsetzung.
Falsche Erinnerungen in der Forschung und der Glaubhaftigkeitsbegutachtung: Ein Kommentar zum Beitrag von Jäckel & Orth (2021)
Authors: Oeberst Aileen , Wachendörfer Merle Madita , Suchotzki Kristina
Published: June 2024

Unsere kürzlich veröffentlichte Studie zur Reversibilität suggestiver Einflüsse auf autobiographische Erinnerungen (Oeberst et al., 2021) nahmen Jäckel und Orth (2021) zum Anlass, deren Bedeutung für die forensische Praxis der Glaubhaftigkeitsbegutachtung zu diskutieren. Dabei kommen sie zu dem Ergebnis, dass „eine praktische Verwendung der Techniken noch nicht hinreichend genug untersucht und empirisch abgesichert ist" (S. 113). Vielmehr bedürfe es der Replikation unserer Befunde sowie auch der Sicherstellung der Reliabilität und externen Validität unserer Ergebnisse. Diesem Fazit stimmen wir uneingeschränkt zu, selbst wenn wir die meisten der angeführten Kritikpunkte—aus unserer Sicht—entkräften können. Wir plädieren allerdings auch dafür, dieselben Anforderungen an die bereits bestehende Praxis der Glaubhaftigkeitsbegutachtung anzulegen: Bislang wurde keine Studie publiziert, welche die Reliabilität und Validität der Analyse der Aussageentstehung und -entwicklung untersucht hat, sodass keinerlei Gütekriterien für diese Praxis existieren. Mehr noch, verschiedene empirische Befunde werfen durchaus Zweifel an einer akzeptablen Reliabilität—und damit auch hinreichenden Validität—des Vorgehens auf.
Perceived Efficacy and the Actual Effectiveness of PowerPoint on the Retention and Recall of Religious Messages in the Weekly Sermon
Authors: Buchko Aaron , Buchko Kathleen , Meyer Joseph ,   Religious Communication Association
Published: June 2024

The purpose of this study was to determine if the use of information communication technology, specifically PowerPoint images, enhanced the effectiveness of the sermon message on congregants’ retention and recall of religious messages. We found that members of a large Protestant church perceived the use of PowerPoint to be efficacious for enhancing understanding, promoting sermon quality, and facilitating retention of information conveyed in the sermon. However, when measuring the actual effect on memory, retention, and recall, PowerPoint did not have a significant effect on members’ actual performance in recalling information from weekly sermons.
NOVEL RP - HPLC METHOD AND DEVELOPMENT AND VALIDATION FOR ESTIMATION OF PHENTERMINE USING BULK AND PHARMACEUTICAL DOSAGE FORM
Authors: G Sowmya
Published: June 2024

A simple and focused HPLC method is described for phentermine measurement. With a C18 column and a mobile phase made up of 40 volumes of methanol, 40 volumes of acetonitrile, and 20 volumes of water, the chromatographic separation was completed at a wavelength of 263 nm. For Phentermine, the method demonstrated linearity in the 50–150 µg/ml range (r2 = 0.990), and the drug amounts found using this suggested method nearly matched the label claim. It is clear from the previously described testing results and parameters that this newly developed approach for phentermine estimate is simple, accurate, exact, and has a high resolution. Its cost-effectiveness and acceptance are further improved by its shorter retention period. In the near future, this technology can be easily implemented for regular studies in research facilities, industry quality control departments, and accredited testing laboratories
AN OVERVIEW OF CITRULLUS COLOCYNTHIS
Authors: Prathap Dr.B. , M Devika. , P Christina Selvi. , C Dharani. , K Dinesh. , R Divya.
Published: June 2024

Citrullus colocynthis (L).schrad (C.Colocynthis), often knownas Colocynth.[FAMILY : Cucurbitaceae]. It is commonlyfound wild in the sandy lands of North West, Punjab and central and Southern India and Coromandal cost. Fruit is Bitter, Pungent and the Fruit are used as a Purgative, anthelmintic, leucoderma, ulcers, asthma etc. Root is useful in Jaundice, ascites, urinary disease, rheumatism.The Pharmacological effects of Root, Fruits, Seeds, Leaves, and the whole CitrullusColocynthis have been practicedfor the treatment of disease. The aim of the study: The present research was undertaken to investigation the Pharmacological activities, Botanical description, Biological sources, Geographical sources, Taxonomic classification, characteristics, Morphological, Nutritional value, Ayurveda and Siddha action. Citrullus colocynthis fruits are containina glycosidees, flavanoids , fatty acids
DESALINATION AND ADVANCED WATER TREATMENT
Authors: Bhardwaj Komal , Kumar Ashwani , Boora Nisha
Published: June 2024

Water scarcity is a global challenge that poses significant threats to human health, food security, and economic development. Desalination and advanced water treatment technologies have emerged as crucial solutions to alleviate water scarcity by converting saltwater and impaired water into freshwater suitable for various purposes. Desalination methods, including Reverse Osmosis (RO), Multi-Stage Flash (MSF) Distillation, Multi-Effect Distillation (MED), and Electro dialysis (ED), enable the conversion of saltwater into freshwater through various processes. Advanced water treatment technologies, such as Advanced Oxidation Processes (AOPs), Membrane Filtration, Activated Carbon Filtration, and Biological Treatment, further purify water from diverse sources, including impaired water and wastewater. These technologies play a vital role in meeting the increasing demands for freshwater while improving water quality. This chapter provides an overview of the principles, methods, and applications of desalination and advanced water treatment, highlighting their significance in addressing water scarcity and promoting sustainability.
ADVANCED ROBOTICS IN DEFENCE AND MEDICAL APPLICATIONS
Authors: Pal Soumayadeep , Banerjee Parthib , Ghosh Avrajeet , Show Ankita , Das Susmita , Ganguly Niladri , Dutta Raktim , Kundu Ankita , Chowdhury Santanu
Published: June 2024

Development of Swarm Bot for Defence and Medical Application Design of Swarm bot is an initiative towards the synchronized performance of multiple bots as a total system consisting huge numbers of plain real-time bots. It is observed that an expected groupwise behavior is expressed from the interactions between the bots and the master device. The head posture movement is used to send the signal from the master device to communicate the slave devices. This methodology has come out in the field of artificial swarm intelligence, as well as the bio-inspired researches of insects and other fields in nature with the occurrence of swarm behavior. This process depends on the master-slave concept to operate the whole system. The wireless communication utilizes the SPI (Serial Peripheral Interface) protocol with radio waves in the range of 2.4-2.5 GHz. The ISM (Industrial Scientific Medical) band is used for the communication purpose. Development of Verticle Climbing Camouflage Surveillance Bot Scientists are trying to make vehicles that can move through both vertical and horizontal planes simultaneously for a long time. Moving against gravity makes it very difficult because of wheel spin in a steeply inclined surface plane. In this paper, we are dealing with the design and development of a WI-FI controlled bot that can move on both horizontal and vertical surfaces. The air suction technique is used to hold the bot on a vertically inclined surface. This paper presents the design and development of a wall climbing bot using an ESP32 CAM microcontroller. The wall climbing feature is achieved by using a 2200kv BLDC motor and 600 mm propeller. When the propeller is rotated using the BLDC motor, the propeller sucks the air underneath the robot, creating a vacuum. As a result, outside air pressure works on the robot and makes it stick to the horizontal surface. The robot`s movement is done by using 4 100 RPM dc motors. The motors are connected to the ESP32 microcontroller via motor driver L298N and can be manually controlled using any ESP32 Android/IOS mobile application. We have used the TCS3200 colour sensor and RGB LED lights to change the colour of the body as per the surroundings. The robot can be used for any surveillance purposes from general surveillance purposes to surveillance of hostile areas.
AUTOMATED DESIGN OF STRUCTURES IN BIM ENVIRONMENT
Authors: Khattra Satinder Kaur
Published: June 2024

BIM, a cutting-edge information technology-based technique, is gaining widespread adoption in the AEC industry. The construction sector is increasingly recognizing the value of incorporating innovative technologies. BIM is being employed by various project stakeholders, including planners, designers, engineers, and subcontractors, to enhance project performance. However, the successful implementation of BIM hinges on the seamless integration and exchange of the extensive data within the BIM model across different project phases and among various parties. The primary obstacle to this success is interoperability, primarily driven by the industry's reliance on proprietary software for data exchange. For the project team to successfully achieve interoperability, vendor-neutral tools and software must be used for communication. In this study, data extraction from an architectural BIM model of a building is done using open-source software to create a structural model. To emphasize that openBIM comprises more than just a standardized file format, an integrated process is designed. This work's main goal is to encourage the use of open-source technologies.
NANOTECHNOLOGY: BOON FOR DISEASE MANAGEMENT IN DIFFERENT CROPS
Authors: Anwar Ali , Gupta Vikas , Nabi Asha , Shahnaz Effat , Wani T. A. , FayazWani Fazil
Published: June 2024

In a world grappling with the challenges of feeding a growing population and ensuring food security, the role of nanotechnology in plant disease management becomes increasingly significant. The integration of nanotechnology in agriculture has emerged as a revolutionary approach for enhancing plant disease management strategies. Nanotechnology, with its focus on manipulating materials at the nanoscale, presents a unique set of tools and strategies that can be harnessed to address the complexities of plant diseases. From targeted delivery of agrochemicals to the development of nanomaterial-based formulations, the possibilities are both exciting and diverse. As we delve into this chapter, we embark on a journey to understand how nanotechnology is reshaping the way we approach plant disease management, offering solutions that are not only effective but also environmentally conscious. This chapter delves into the intricate relationship between nanotechnology and plant health, highlighting the unprecedented opportunities and advancements it offers in combating various plant diseases. Additionally, the challenges and ethical considerations associated with the widespread adoption of nanotechnology in plant disease management are critically examined. Through a synthesis of current research and technological advancements, this chapter aims to provide readers with a nuanced understanding of the transformative potential of nanotechnology in revolutionizing plant disease management. As the agricultural landscape faces escalating challenges from emerging pathogens and environmental stresses, embracing nanotechnology offers a promising avenue for sustainable, efficient, and eco-friendly solutions to safeguard global food security.
PLANT PROTECTION EQUIPMENT FOR CHEMICAL APPLICATION ON CROP TO EFFECTIVELY CONTROL PESTS AND DISEASES
Authors: Kadam D. M. , Shrivastava A.K. , Panse R.K. , Prveeen Kalluri
Published: June 2024

Pesticides play an integral role in the control of pests such as insects, fungi and weeds on field crop and orchards, to produce and conserve food grains, fruits, vegetables and fibre. All insects are not pests. Some help in pollinating plants or feeding on other insects which are pests. Control of pests is a need to protect crop for better yield. Proper use of pesticide is however a critical. Excessive dosage may damage or even kill the plant, whereas under dosage will not give effective control. Desirable flora and fauna and environment may be harmed by indiscriminate use of pesticides. Success of plant protection will depend upon the use of right pesticide, at the right time, with the right technique and by the right equipment. So, an attempt has been made in this chapter to makes aware and familiar farmers, researchers, scientists and readers, with the plant protection equipment, their basic classification, basic components of sprayers, nozzle and their types, brief description of various types of sprayers and dusters used for plant protection, selection of plant protection equipment, calibration of plant spraying equipment, maintenance of plant protection equipment, safety precautions to be taken by operator before, during and after spraying etc. This crucial information on plant protection equipment will be useful for effectively controlling pests and diseases on field crops as well as orchards.