bluuebunny/crossref_metadata_2025 huggingface dataset:
La internacionalización de las Mipymes de Costa Rica desde la perspectiva de la Cadenas Globales de Valor
Authors: Yan Li
Published: October 2024

Con el desarrollo de la globalización económica, cada vez mayor número de Mipymes están participando en la cadena de valor global y Costa Rica, país situado en América Central se incorpora a tal proceso. Este artículo tiene por objetivo analizar el nivel de internacionalización de las Mipymes costarricenses en los últimos años, sobre todo, durante el periodo 2000-2012, a través de los siguientes cuatro indicadores: el número de exportaciones, el valor de las exportaciones, los destinos y los tipos de los productos exportados. El artículo concluye que el nivel de internacionalización de las Mipymes de este país ha aumentado de manera constante. Motivos favorables como el apoyo gubernamental, la identificación adecuada de la posición de las empresas, la elección de los apropiados modelos de internacionalización y el aprovechamiento de las ventajas de los conglomerados industriales han contribuido a que las Mipymes de Costa Rica avancen desde la parte baja a media de la cadena de valor global hacia la parte alta, logrando así su internacionalización.
AI through the eyes of university students: benefits, concerns and possible challenges
Authors: PARSHUTINA G.A. , KAMALETDINOVA S.M.
Published: October 2024

The article discusses the issues related to the application of artificial intelligence (AI) within the environment of the senior bachelor's and master's degree students of different universities. To that end the method of questionnaire was implemented based on the online test constructor Testmoz, which comprised 10 questions of both closed and open-ended types. The observations and conclusions presented are based on the results of analyzing students' perceptions and usage patterns of neural network-based applications, in particular in English studies. Assignments on developing students’ competences in mastering a foreign language are exemplified. The study shows how often, to what extent and which tools they rely on, how much AI affects students' learning and performance, and what their concerns are in terms of its increasing integration into education. The peculiar features of chatbots as the most popular “assistants” in learning are considered, with a special emphasis on Chat GPT (Generative Pre-trained Transformer); according to students’ evidence, it is in high demand in carrying out various academic and research tasks. In addition, the study analyzes the challenges that teachers are facing and those that will have to address, such as ensuring fair assessment, addressing issues of trust and credibility, and adapting to the changing educational landscape heavily influenced by AI. The results of the study emphasize the need for a balanced approach to the use of neural network technology in education, taking into careful consideration ethics, data privacy, and the importance of maintaining critical thinking skills.
Early Haemorrhage Postpartum (HPP); With Complication Disseminated Intravascular Coagulation, Sepsis, Acute Kidney Injury
Authors: Oktavian Rizki , Gunawan Efri  , Sriyanti Roza , Taslim Emilzon
Published: October 2024

Background : Hemorrhage Postpartum (HPP) is the leading cause of maternal death worldwide with an incidence of 5%-10% of all deliveries. 70% of cases of HPP are caused by atony of the uterus. If HPP is not handled properly, it will cause worsening of the patient's condition which causes various multiorgan complications.
Objectives : To discuss the management of HPP cases complicated by DIC, sepsis and AKI.
Method : case report.
Case : A female patient, 36 years old, was referred from a private hospital to PONEK RSUP Dr. M. Djamil Padang with a diagnosis of decreased consciousness ec suspected sepsis in post SCTPP oi used SC 2x + post relaparotomy oi bleeding subfascia + moderate anemia. After surgery, the patient looked pale and the hemoglobin was 7, then relaparotomy was done and done B-lynch oi uterine hypotony. After relaparotomy, the patient experienced worsening then referred to the hospital. The patient arrives with hipovolemic shock + AKI + Sepsis + DIC , then the condition improvement is carried out in ROI and hysterectomy relaparotomy is performed. The patient has worsened, maximum treatment has been carried out from the intersivist, but the patient's condition continues to worsen and eventually dies.Conclusion : Early diagnosis and rapid treatment through a multidisciplinary team and the availability of an Intensive Care Unit (ICU) can prevent complications and reduce morbidity and mortality.
Perbaikan dan Penataan Ulang Instalasi Listrik Mushalla Al-Barkah Rimbo Panjang
Authors: Rahmi Berlianti  , Efendi  , Ihsan L. Rimra  , Julsam  , Nazris Nazaruddin  , Wiwik Wiharti  , Oktavia Aulia
Published: October 2024

Instalasi listrik adalah pemasangan beberapa peralatan listrik yang saling berhubungan yang sesuai dengan standar PUIL. Pemasangan yang sesuai standar dapat menjamin keselamatan jiwa manusia khususnya jamaah Mushalla Al-Barkah. Mushalla Al-Barkah Batu Busuk ini merupakan mushalla yang baru didirikan oleh masyarakat sekitar sehingga instalasi listriknya masih belum sesuai dengan standar PUIL. Artikel ini membahas strategi perbaikan dan perawatan instalasi listrik pada musholla guna meningkatkan keamanan dan kenyamanannya. Perbaikan dan perawatan instalasi listrik pada musholla melibatkan serangkaian tindakan, diantaranya inspeksi menyeluruh, identifikasi permasalahan, perbaikan sesuai standar keselamatan listrik yang berlaku dan perawatan. Identifikasi permasalahan melibatkan pemeriksaan perangkat listrik, seperti kabel, sakelar, stop kontak, serta sistem grounding. Selanjutnya, langkah perbaikan akan dilakukan untuk mengatasi masalah yang ada dan memastikan kinerja instalasi listrik secara optimal. Perawatan rutin juga sangat penting untuk memastikan keberlangsungan fungsi instalasi listrik. Perawatan ini meliputi pembersihan, pelumasan, dan penggantian komponen yang telah mencapai masa pakainya. Penerapan tindakan preventif ini akan membantu menghindari potensi kerusakan dan mencegah gangguan listrik yang dapat mengganggu aktivitas ibadah di musholla. Dengan melakukan perbaikan dan perawatan secara berkala, diharapkan instalasi listrik pada musholla dapat beroperasi secara optimal, mengurangi risiko kecelakaan akibat korsleting atau kebocoran arus listrik. Selain itu, keamanan dan kenyamanan para jamaah dalam beribadah juga akan terjamin, menciptakan lingkungan yang aman dan nyaman untuk beribadah. Diharapkan, hasil dari penelitian ini dapat menjadi acuan bagi pemilik dan pengelola musholla dalam memastikan instalasi listrik yang baik dan layak digunakan, sehingga mengoptimalkan manfaat musholla sebagai tempat ibadah bagi seluruh umat.
Effect of an Indian Percussion Music Instrument on the Oral Health, Motor Skills and Social Skills of Children with Autism
Authors: Shukla Balraj , Panda Anup , Budakoti Varsha , Mehta Jay , Kevadiya Mili
Published: October 2024

Background: Children with Autism Spectrum Disorder (ASD) are characterized by deficit in social skills. Motor skill impairments and poor oral health are consistent with these individuals. An intervention targeting an improvement in multiple deficits of ASD needs to be developed. This study aimed to improve the oral health status, motor skills and social skills of children with autism by means of a music therapy involving self-playing a percussion music instrument. Methods: This study employed a randomized controlled trial design where children with autism between 4-12 years of age were divided into a control (n=12) and an experimental (n=12) group. Both groups were given the music therapy that involved training in playing the Tabla. The control group received only oral hygiene instructions whereas the experimental group received a music therapy intervention along with the oral hygiene instructions. Standardized scales were used for measuring the oral health status, motor skills and social skills. Descriptive independent t-test was done for intergroup comparison and paired t-test was done for intragroup comparison. Results: There was a significant change in the plaque index, motor skills, social participation and social reciprocation of the participants in the experimental group. Conclusion: This study showed that music therapy for children with autism through playing the Tabla shows potential for improving their oral health, motor skills and social skills.
Exploring the Relationship between Visual Memory Consolidation and Dreaming During the Transition from NREM to REM Sleep: A Systematic Review
Authors: Shiv Shankar Aditya , Shankaran Ashwin
Published: October 2024

This systematic review investigates the intricate relationship between visual memory consolidation and dreaming during the transition from Non-Rapid Eye Movement (NREM) to Rapid Eye Movement (REM) sleep in human subjects. Recognising the pivotal role of these sleep stages in memory processes and dreaming, we employed a comprehensive search strategy to identify relevant literature. A total of 23 studies were included in the quantitative synthesis, focusing on methodologies assessing visual memory and dreaming experiences during the NREM-REM transition. Each study underwent rigorous evaluation for risk of bias to ensure the reliability and validity of findings, with those identified as having a high risk of bias given less weight in result synthesis. Our analysis highlights the importance of understanding the interplay between visual memory consolidation and dreaming during the NREM-REM transition, shedding light on fundamental aspects of sleep-dependent memory processes and dreaming.
Evaluating the readability, quality and reliability of online patient education materials on chronic low back pain
Authors: OZDURAN ERKAN , HANCI VOLKAN , ERKIN YUKSEL
Published: October 2024

Background

There are concerns over the reliability and comprehensibility of health-related information on the internet. We analyzed the readability, reliability and quality of online patient education materials obtained from websites associated with chronic low back pain (cLBP).

Methods

On 26 April 2022, the term ‘cLBP’ was used to perform a search on Google, and 95 eligible websites were identified. The Flesch Reading Ease Score (FRES) and Gunning Fog (GFOG) index were used to evaluate the readability. The Journal of the American Medical Association (JAMA) score was used to assess the reliability and the Health on the Net Foundation code of conduct (HONcode) was used to assess quality.

Results

The mean (SD) FRES was 55.74 (13.57) (very difficult) and the mean (SD) GFOG was 12.76 (2.8) (very difficult) of the websites reviwed. According to the JAMA scores, 28.4% of the websites had a high reliability rating and 33.7% adhered to the HONcode. Websites of different typologies were found to significantly differ in their reliability and the quality scores (p<0.05).

Conclusion

The reading ability required for cLBP-related information on the internet was found to be considerably higher than that recommended by the National Health Institute and had low reliability and poor quality. We believe that online information should have readability appropriate for most readers and must have reliable content that is appropriate to educate the public, particularly for websites that provide patient education material.
Analysis of the Relationships between Residents’ Perceived Social Impacts of a Publicly Subsidized Multipurpose Facility and Behavioral Intentions
Authors: Kim Wonyoung , Lim Namhun , Rhee Yong-chae
Published: October 2024

Despite challenging economic conditions, municipalities have justified the utilization of public subsidies to build or renovate multipurpose sports facilities due to the lack of modern features and the aging of existing facilities. To secure public support for the utilization of public subsidies, promises are often made about the transformative potential of events and teams for the community. The current study aims to examine the relationship between residents’ perceived social impact and their behavioral intentions regarding a newly developed multipurpose sports facility. The survey instrument was administered to assess residents' perceived social impacts related to the multipurpose sports facility as well as their behavioral attributes. The findings revealed that perceived social impacts such as community development and economic benefits significantly influenced the attendance of future sports and entertainment events as well as word-of-mouth on sports and entertainment events. Respondents’ level of involvement and attendance in sports and entertainment events were significant predictors of positive behavioral intentions and word-of-mouth. Lastly, certain demographic variables indicated significant relationships with behavioral attributes. This study highlights the importance of understanding residents’ perceived social impact concerning their behavioral attributes. The findings can be used by policymakers and administrators to plan and execute the facility development using public subsidies, aiming to reduce social conflicts and enhance social cohesion among residents
Features of China's Approach to AI Security: Development Strategy in Relation to Law and Standardization
Authors: Володина Н.В.
Published: October 2024

В ближайшие годы предполагается бурное развитие технологий искусственного интеллекта и появление более сложных систем, других типов ИИ, предоставляющих новые большие возможности, но одновременно провоцирующие возникновение новых проблем. Множество научных исследований посвящено сфере искусственного интеллекта, именуемой «технологией массового использования». Актуальное значение имеют правовое регулирование и государственная поддержка системы и технологий ИИ. Китайская Народная Республика вырабатывает специфический подход к развитию системы искусственного интеллекта и свою стратегию, планируя создать цифровое правительство и разрабатывая конституционно-правовые основы для регулирования ИИ на государственном и региональном уровне при осуществлении плана по развитию искусственного интеллекта нового поколения. В статье обращается внимание на принципы цифровой этики, а также на риски, которые возникают при использовании ИИ.

In the coming years, it is expected that artificial intelligence technologies will rapidly develop and more complex systems, other types of AI will emerge, providing new great opportunities, but at the same time provoking the emergence of new problems. Many scientific studies are devoted to the field of artificial intelligence, called "mass use technology". Legal regulation and state support for the AI ​​system and technologies are of current importance. The People's Republic of China is developing a specific approach to the development of the artificial intelligence system and its own strategy, planning to create a digital government and developing a constitutional and legal basis for regulating AI at the state and regional levels when implementing a plan for the development of new-generation artificial intelligence. The article draws attention to the principles of digital ethics, as well as the risks that arise when using AI.
Legal Positions of the Constitutional Court of the Russian Federation on Ensuring the Constitutional Right of Citizens to Housing
Authors: Чирейкин Н.М.
Published: October 2024

В статье дается обзорный анализ теоретических основ правовых позиций Конституционного Суда РФ, вынесенных, в частности, по вопросам ограничения конституционного права на жилище в делах о несостоятельности (банкротстве) должников. Предпринимается попытка обозначить возможности восполнения пробелов в праве, выявленных или созданных в результате реализации деятельности Конституционного Суда РФ. Отмечается необходимость решения проблемы ограничения и пределов реализации конституционного права на жилище с учетом пересечения публичных и частных интересов.

The article provides an overview analysis of the theoretical foundations of the legal positions of the Constitutional Court of the Russian Federation, in particular, those issued on the limitation of the constitutional right to housing in cases of insolvency (bankruptcy) of debtors. An attempt is being made to identify the possibilities of filling gaps in the law identified or created as a result of the implementation of the activities of the Constitutional Court of the Russian Federation. It is noted that it is necessary to solve the problem of limitations and limits of the implementation of the constitutional right to housing, taking into account the intersection of public and private interests.
Federal Law "On Probation in the Russian Federation" and its Implementation
Authors: Громов В.Г. , Шошин С.В.
Published: October 2024

В статье анализируется Федеральный закон «О пробации в Российской Федерации». Пробация рассматривается в качестве механизма альтернативного уголовного наказания. Отмечаются недостатки и преимущества системы пробации и ее воздействие на уголовное правосудие. С учетом снижения общей численности лиц, находящихся в условиях лишения свободы по приговору суда, предлагается развитие подобной практики. Одним из направлений совершенствования процедуры пробации можно назвать распространение возможности ее применения на страны Содружества Независимых Государств и иные межгосударственные объединения. Авторы полагают, что в итоге серьезной научной и общественной дискуссии закон о пробации, претерпев ряд изменений, смог бы внести позитивный вклад в процессы исправления преступников и профилактику рецидива преступлений.

The article analyzes the Federal Law "On Probation in the Russian Federation". Probation is considered as a mechanism of alternative criminal punishment. The disadvantages and advantages of the probation system and its impact on criminal justice are noted. Taking into account the decrease in the total number of persons in prison under a court sentence, the development of such a practice is proposed. One of the areas for improving the probation procedure can be called the extension of the possibility of its application to the countries of the Commonwealth of Independent States and other interstate associations. The authors believe that as a result of serious scientific and public discussion, the probation law, having undergone a number of changes, could make a positive contribution to the processes of correction of criminals and the prevention of recidivism.
Status of the Prosecutor in Arbitration Proceedings in Cases of Administrative Offenses
Authors: Алиев Т.Т. , Алиев Р.Т.
Published: October 2024

В статье рассматривается проблема определения статуса прокурора в арбитражном процессе по делам об административных правонарушениях. Проблема заключается в том, что законодатель не регламентирует возможность подачи прокурором заявления об административных правонарушениях в арбитражный суд, однако федеральным законодательством о прокуратуре такая обязанность установлена. Арбитражный суд вынужден действовать на основании установленной судебной практики и постановлений пленума Высшего Арбитражного Суда Российской Федерации. Судебная практика самостоятельно регламентирует возможность прокурора подавать заявления об административном правонарушении. При этом вопрос о статусе прокурора остается открытым, хотя арбитражное законодательство устанавливает статус прокурора как процессуального истца. В работе проведен анализ законодательства, судебной регламентации и юридической доктрины относительно вопроса статуса прокурора.

The article examines the problem of determining the status of a prosecutor in arbitration proceedings on administrative offenses. The problem is that the legislator does not regulate the possibility of filing a statement of administrative offenses to an arbitration court by a prosecutor, but the federal legislation on the prosecutor's office establishes such an obligation. The arbitration court is forced to act on the basis of established judicial practice and decisions of the plenum of the Supreme Arbitration Court of the Russian Federation. Judicial practice independently regulates the possibility of a prosecutor to file statements of administrative offenses. At the same time, the question of the status of a prosecutor remains open, although arbitration legislation establishes the status of a prosecutor as a procedural plaintiff. The paper analyzes legislation, judicial regulation and legal doctrine regarding the issue of the status of a prosecutor.
On the Issue of the Grounds of Administrative Coercion
Authors: Куракин А.В. , Елбаева Н.А. , Козырева Ю.Н.
Published: October 2024

Рассматриваются основания действия административного принуждения. Этот вопрос важен с точки зрения применения различных мер административного воздействия предопределятся соблюдением требований законности. Правильная оценка оснований административного принуждения может дать возможность сбалансировать частные и публичные интересы в деле применения различных мер административного принуждения, а также избежать нарушений требований законности.

The grounds for administrative coercion are considered. This issue is important from the point of view of applying various measures of administrative influence. A correct assessment of the grounds for administrative coercion can make it possible to balance private and public interests in the application of various measures of administrative coercion, as well as to avoid violations of the requirements of legality
From Reverse Phase Chromatography to HILIC: Graph Trans-formers Power Method-Independent Machine Learning of Retention Times
Authors: Stienstra Cailum , Nazdrajić Emir , Hopkins W. Scott
Published: October 2024

Liquid chromatography (LC) is a cornerstone of analytical separations, but comparing the retention times (RTs) for different LC methods is difficult because of variations in experimental parameters such as column type and solvent gradient. Nevertheless, RTs are powerful metrics in tandem mass spectrometry (MS2) that can reduce false positive rates for metabolite annotation, differentiate isobaric species, and improve peptide identification. Here, we present Graphormer-RT, a novel graph transformer that performs the first “method-independent” prediction of RTs. We use the RepoRT dataset, containing 142,688 reverse phase (RP) RTs (191 methods) and 4,373 HILIC RTs (49 methods). Our best RP model achieved a test set mean average error (MAE) of 29.3±0.6 s, a significant improvement over the previous record (1 method). Our best performing HILIC model achieved a test MAE=42.4±2.9 s. Extending this proof-of-concept work could enable machine-optimization of automated LC workflows and in silico annotation of unknown analytes in LC-MS2 measurements.
High-Pressure Electrides: A Quantum Chemical Perspective
Authors: Racioppi Stefano , Zurek Eva
Published: October 2024

It has long been assumed that all matter will assume simple closed-packed lattices and become metallic under pressure, in accordance with the Thomas-Fermi-Dirac (TFD) model. However, this model struggles to explain pressure driven complex structural transitions that have been observed in elements, including sodium, challenging our conventional understanding of compressed matter. Moreover, in stark contrast to the TFD picture, first-principles calculations suggest that various elements and compounds become electrides under pressure. Electrides, characterized by concentrations of charge density at interstitial regions, can be thought of as ionic compounds where electrons behave as the anions. Though ambient-pressure molecular electrides have been extensively studied via experiments and computations, high-pressure electrides (HPEs) are not well understood. The identification and characterization of HPEs has been, to date, purely based on theory including topological analysis of the electron density and the electron localization function. Here, we review these theoretical analyses tools and suggest guidelines that can be used to classify systems as electrides. Moreover, we describe models used to rationalize the electronic structure of HPEs, drawing parallels with ambient pressure molecular systems, and urge for the development of experimental techniques that provide evidence for the theoretically calculated charge localization.
On intimate care in men: A review
Authors: Niewozinska Zofia A. , Sakaniya Luiza R. , Korsunskaya Irina M.
Published: October 2024

Even though intimate hygiene plays an essential role in the prevention of various genital diseases, there are currently few studies on this topic. There is a wide range of diseases that affect the male genital organs. There is a wide range of diseases that affect the male genital organs. Inflammation of the glans penis (balanitis) occurs in 3–11% of males during their lifetime; one of its leading causes is poor hygiene. However, many non-venereal dermatoses occur in this anatomical region. Most often, patients complain of itching, as well as pain, burning, and various rashes. The most common reason for seeking medical attention is irritant contact dermatitis. Various allergens cause more acute reactions in the anogenital region due to the structural features of the skin of the genitals. Components of detergents and hygiene products, accessories for sexual practices, medications, and contraceptives can become provoking factors of genital allergic dermatitis. Among the dermatoses affecting the male genitalia, lichen planus should be noted, which occurs in males twice as often as in females, and the oral mucosa is often involved in the inflammatory process. Lichen sclerosus can also occur on the skin of the penis, leading to phimosis, a decrease in quality of sexual life, and often requiring circumcision. Psoriasis also can affect the anogenital area. Rashes may be isolated, but other anatomical areas are also involved in most cases. Psoriatic lesions of the genitals are visually different from typical elements in other areas of the skin. Minimizing discomfort due to these diseases is possible by using specialized care products. The skin of the genitals in men has specific features that are important to consider when developing the composition of the products.
Pityriasis rubra pilaris: A review
Authors: Adaskevich Vladimir P.
Published: October 2024

Pityriasis rubra pilaris (PRP, syn.: Devergie's disease) is a rare idiopathic papulo-squamous inflammatory skin disease characterized by follicular papules, palmar-plantar keratoderma, scaling plaques of orange-red color with characteristic foci of unaffected skin. Histologically, the alternating pattern of orthokeratosis and parakeratosis is considered a distinctive feature of PRP (staggered hyperkeratosis). A violation of the regulation of innate immunity is a component of the pathogenesis of PRP. Congenital mutations of CARD 14 or concomitant antigens, which can take the form of iatrogenic lesions, infections or malignant neoplasms, can be the initial triggers of the disease, although the etiology is often idiopathic. There are classically five subtypes of the disease, depending on the age of onset and clinical picture. Type VI PRP is associated with infection caused by the human immunodeficiency virus. CARD 14-associated papulosquamous rash and discoid dermatitis of the face represent new clinical phenotypes of PRP. Devergie's disease has a pronounced negative impact on the quality of life, and those who become ill are at increased risk of depression and suicide. Ixekizumab, methotrexate and secukinumab can be considered as systemic drugs of the first choice. If there is a contraindication to immunosuppressive therapy, high doses of isotretinoin are recommended. Topical agents, including calcipotriene, calcineurin inhibitors, emollients and topical corticosteroids, are used as additional therapy.
Skin infections in atopic dermatitis: clinic, treatment. A review
Authors: Macharadze Dali Sh.
Published: October 2024

Infection is the most common complication of atopic dermatitis (AtD). In particular, some patients with AtD exhibit increased susceptibility to skin infections of bacterial, viral, and fungal etiologies. In some cases, infections can even be systemic. Bacterial skin infections are more common than viral and fungal ones. An especially severe infection caused by the herpes virus is herpetic eczema, which can cause life-threatening complications. Infections of fungal etiology are represented mainly by the Malassezia species, especially in patients with dermatitis of the head and neck. The review focuses on the pathophysiological mechanisms identified to date that are thought to predispose to skin infections. The main ones are impaired skin barrier function, complex immunological changes, as well as poorly understood factors such as environmental exposure and skin dysbiosis. The review also includes the clinical characteristics of patients with various skin infections, as well as appropriate treatment for complications of AtD.
The influence of blue light sources on somnological disorders among patients with mild to moderate acne
Authors: Yakovleva Evgenia N. , Perlamutrov Yuri N.
Published: October 2024

Background. The acne is a chronic inflammatory skin disease that affects all age groups of the population and has a serious impact on the quality of life of patients. Various endogenous and exogenous factors are involved in the pathogenesis of dermatosis. The increasing of usage of digital media and the Internet has an impact on people's sleep habits and, with changes in sleep quality, symptoms of depression, anxiety and stress may increase, which leads to a more severe course of chronic dermatoses, including acne.
Aim. To evaluate the relationship between somnological disorders (SLD) and the frequency of smartphone use before bedtime in patients with mild to moderate acne (MMA).
Materials and methods. A single-center observational prospective study was conducted from 2023 to 2024: 130 patients aged 18 to 30 years (average age 23.32±2.75 years) diagnosed with MMA were observed. The data on the severity of acne were assessed using the Global Acne Grading System (GAGS), the degree of sleep disturbance was determined using the Pittsburgh Sleep Quality Index (PSQI), and the quality of life of patients was determined according to the Dermatology Life Quality Index (DLQI). Taking into account indicators on the use of a smartphone with the iOS or Android operating system included calculating average screen time, assessing addiction and the fact of using a smartphone 1 hour before bedtime. The statistical processing was carried out using the Jamovi version 2.3.21 program.
Results. The SLD were identified in 85 (65.38%) patients with MMA. The dermatosis had a strong impact on quality of life (DLQI20) in 82.31% (n=107). In group I of patients "poor sleeping" there was a direct correlation between SLD (PSQI) and the severity of dermatosis (ρ=0.533; p0.001) and the duration of screen time (ρ=0.628; p0.001) spent on a smartphone per day. The patients of group I had a greater dependence on a smartphone compared to group II of patients "well sleeping": 15.94±1.89 points versus 7.71±1.96 points (p0.001).
Conclusion. It has been established that the level of SLD has a high incidence in the group of patients with MMA. There is a pronounced correlation between dyssomnia and the severity of dermatosis; in patients with disturbed sleep, a high dependence on the phone and a correlation with the duration of screen time spent on a smartphone per day were revealed. This study demonstrates the need to pay attention to the presence of disturbances in the quality of sleep in people suffering from skin diseases, in particular acne.
Adalimumab: A key element in the treatment strategy for immune-mediated inflammatory diseases: A review
Authors: Gilavian Mariam A. , Trunova Daria V. , Ustinova Anastasia V. , Sukhanova Anna M.
Published: October 2024

Adalimumab is a biological drug effectively used in the treatment of several immune-mediated inflammatory diseases, including ankylosing spondylitis, juvenile idiopathic arthritis, and psoriasis. This study analyzed the therapeutic and economic benefits of adalimumab. Patients with ankylosing spondylitis showed significant improvements in quality of life and work productivity after treatment with adalimumab, confirming its clinical and economic efficacy. In the case of juvenile idiopathic arthritis and psoriasis, adalimumab demonstrated high efficacy and safety, significantly improving patients' conditions, establishing it as the gold standard of therapy. The use of adalimumab biosimilars offers accessible alternatives to the original drugs, expanding treatment options and reducing the economic burden on patients.
Plasmapheresis in the treatment of post-COVID syndrome in dermatology. Case report
Authors: Katkova Ksenia V. , Chekh Aleksandr S. , Zhukova Olga V. , Denisova Elena V. , Korsunskaya Irina M.
Published: October 2024

The relevance of studying the impact of coronavirus infection on the development and course of autoimmune diseases is due to an increase in the incidence of COVID-19 infection, which is confirmed by reliable data from recent large-scale studies. The trigger mechanisms of autoimmune disorders, particularly those with dermatological manifestations, have been well studied. COVID-19 significantly increases not only the risk of manifestation of autoimmune diseases but also the transformation of a preexisting disorder into severe, atypical, and resistant to standard therapy forms. The article analyzes the data of patients with psoriasis treated in a day hospital from 2021 to 2023 at the affiliate of the Moscow Scientific and Practical Center of Dermatology, Venereology and Cosmetology “V.G. Korolenko Clinic” with exacerbation or onset of the disease reliably associated with a history of coronavirus infection. It is a clinically significant issue since there is a pathomorphosis of a typical pattern of exacerbations: the area of skin lesions increases, exudative and toxicoallergic components are manifested; psoriasis is torpid, which requires the development of individual algorithms for the treatment of patients with psoriasis and post-COVID syndrome, considering the mechanisms of this condition development. An essential aspect in the analysis of this sample of patients was the assessment of general somatic comorbidity, which requires a multidisciplinary approach in selecting therapy to comply with modern criteria for quality treatment, namely its maximum effectiveness and safety.
Problematic issues of the impact of microplastics on the human body and the environment: A review
Authors: Pupykina Viktoria V. , Zakharova Irina N.
Published: October 2024

Currently, the widespread use of plastic has become a serious problem for the environment and human health. Microplastics, being an artificial polymer created by man, are highly resistant to external influences and their decomposition requires a significant amount of time. The article provides information on the distribution of microplastics and their impact on the environment and the human body, issues of detecting microplastics in the blood, heart, lungs, placenta and meconium, in breast milk, hypothetical mechanisms by which microplastics penetrate into human tissues and the metabolism of plasticizers in children with autism spectrum disorder and attention deficit hyperactivity disorder. In the modern world, plastic has become an integral part of our daily lives, the presence of microplastics in plastic bags for storing breast milk, in baby formula and polypropylene bottles has been demonstrated, the relationship between microplastics and postpartum depression, the relationship between fecal microplastics and the status of inflammatory bowel diseases has been described. Making the decision to limit the use of plastic products in your home is an important step that can play a key role in reducing environmental pollution and protecting the health of future generations.
Analysis of strategies for increasing the competitiveness of jackfruit chips small
medium enterprises in Malang Regency, Indonesia
Authors: Novia C. , Syaiful S. , Utomo D.
Published: October 2024

Jackfruit chips small and medium enterprises (SMEs) in Malang Regency play an
important role in national economic growth. The purpose of this study was to find a
strategy to improve the competitiveness of jackfruit chips in Malang Regency. Technical
analysis of research data was conducted using analysis of external and internal factors and
the concept of the house model for determining strategies for increasing the
competitiveness of jackfruit chips SMEs in Malang Regency. The results showed that by
increasing product variables, improving human resources and marketing institutions could
be a strengthening strategy for increasing the sustainable competitiveness of jackfruit
chips SMEs.
යටත් විජිතයේන් සුන්බුන් නොවු අනන්‍යතාවය: A Critical Autoethnographic Journey of a Sri Lankan Music Therapy Student in Aotearoa
Authors:   , Jayawardena Amodini
Published: October 2024

This research explored how a student music therapist’s journey in relearning and reconnecting with her Sri Lankan cultural roots informed her practice as a student music therapist. Critical autoethnography was used to examine how the exploration of one’s own paramparāva and ethnic culture(s) impacted on practice, revealing the fragility of one’s perceived truths and realities. A postcolonial lens was used, guided by the work of Hommi K. Bhabha. The first data set was generated from a student music therapist’s learnings and reflections about her Sri Lankan culture through literature, pavula, and pavulē mituran knowledge. The second data set was generated from this student music therapist’s practice and reflexive journal. These data sources were thematically analysed using both inductive and deductive approaches. Seven themes emerged for the data analysis: 1) Journeying through my paramparāva, 2) “Sri Lankan-ness”, 3) Postcolonial hybrid Sri Lankan ananyatāvaya, 4) Introspection (from the data about Sri Lankan culture), 5) Culture centred music therapy, 6) My music therapy style, and 7) Introspection (from the student music therapist’s practice). From the findings emerged the practice model “Dynamic Ripple”. This model positioned the student music therapist and participant(s) in mahi tahi. The model exposed colonisation as our constant contemporary, and the induction of the shift to a decolonisation mindset of the student music therapist’s self and practice.
On the Construction of Regular Solutions for a Class of Generalized Cauchy–Riemann Systems with Coeﬃcients Bounded on the Entire Plane
Authors: Baizaev S. , Barotov R. N.
Published: October 2024

This article explores the generalized Cauchy–Riemann system on the entire complex plane. The coeﬃcient for the conjugation of the desired function belongs to the Hölder space and, for |z| > 1 , equals eimϕ , where m is an integer. For m ≤ 0 , the system was shown to have no nonzero solutions that grow no faster than a polynomial. For m ≥ 0 , the complete set of regular solutions, i.e., those without singularities in the ﬁnite part of the plane, was constructed. The obtained solutions were expressed as series of Bessel functions of an imaginary argument. From the resulting set, the solutions bounded on the entire plane were distinguished, and the dimension of the real linear space of these solutions, which equals m , was determined.
Situating Integration (Mixing) Within Mixed Methods Research: A Review of the Methodological Literature
Authors: Sylvester John
Published: October 2024

Mixed Methods Research (MMR) provides great research approach for investigating complex problems and systems. MMR is seen as the latest and more pragmatic approach in the field of social science. It has the opportunity of mixing the strengths of both quantitative (QUAN) and qualitative (QUAL) research approaches in one study but also the challenges of integrating (mixing) these strengths into the process. This review of methodological literature seeks to address possible integration that might occur within an MMR. Integration can occur at one stage, or multiple stages of a mixed methods research study. Understanding the different stages of integration within a mixed methods research study can greatly improve the professional research dexterity of researchers. Integration strategies are discussed to provide mixed methods researchers with the opportunities meaningfully to integrate the QUAN and QUAL approaches within an MMR. Possible challenges of integration also are discussed in this article.
Recent Advances, Future Directions and Clinical Outcomes of Hepatectomy in Hepatocellular Carcinoma
Authors: Muhammad Tauqeer , Chattha Hashim Nazir , Chattha Ahmad Nazir , Jiang Li , Hong Zhu
Published: October 2024

Background: Hepatocellular carcinoma (HCC) represents the predominant and most fatal malignancy globally. The primary therapeutic approach for HCC is Hepatectomy, which presents a potential for curative outcomes. This analysis aims to offer an exhaustive examination of the clinical repercussions linked to liver resection or Hepatectomy in HCC, underscore recent advancements in surgical methodologies, and deliberate on future pathways to enhance treatment efficacy in this domain. Methods: A thorough exploration of the literature was carried out across prominent databases, including Google Scholar, PubMed, ScienceDirect, and Cochrane Library. Research articles were chosen based on their pertinence to the outcomes of Hepatectomy in HCC, advancements in surgical techniques, and forthcoming therapeutic schemes to scrutinize the short- and long-term clinical consequences and the variables influencing these outcomes. Results: Hepatectomy for HCC manifests notable diversity in clinical outcomes, impacted by the nature of the tumor, characteristics of the patient cohort, and proficiency of the surgical team. Short-term results, like perioperative morbidity and mortality rates, have demonstrated enhancements in tandem with refinements in preoperative evaluations and intraoperative management. The duration of outcomes, encompassing overall survival and disease-free survival, displayed significant associations with extended resections, tumor characteristics, and postoperative assessments. Recent progressions in Hepatectomy have played a role in diminishing perioperative complications and expediting the recovery process. Furthermore, the amalgamation of adjuvant and neoadjuvant therapies, alongside the emergence of pharmaceutical modalities, can elevate survival rates and enhance the quality of life for individuals with HCC. Conclusion: Hepatectomy emerges as a pivotal intervention for HCC, yielding progressively superior outcomes owing to technological advancements and enhanced perioperative care. Prospective investigations will refine surgical techniques, optimize adjuvant therapies, and formulate robust predictive frameworks for diverse therapeutic modalities. This comprehensive assessment accentuates the significance of sustained innovation and interdisciplinary cooperation to elevate the standard of care for HCC patients. Moreover, continuous investigation into adjuvant and neoadjuvant treatments, such as immunotherapy and targeted therapies, is imperative for enhancing long-term prognoses.
Aplicaciones de la ecuación de Griffith en el estudio de la grieta desarrollada en elementos mecánicos sujetos a esfuerzos axiales, que trabajan bajo condiciones de envejecimiento acelerado
Authors: Flores Báez Misael , Flores Baez Israel , Sanchez Cervantes Arturo , Urriolagoitia Sosa Guillermo , Barajas Ambriz Israel Fernando , Ramirez Sanchez Gabriela
Published: October 2024

Los componentes mecánicos a menudo sufren fracturas debido a porosidades que se forman y se convierten en grietas debido a esfuerzos y la exposición al medio ambiente, sobre todo cuando trabajan en ambientes agresivos. Debido a esto es necesario estudiar y simular los aspectos que causan estas fracturas de forma inicial y así entender cómo se desarrollan y propagan. La mecánica de la fractura generalmente se aplica cuando el componente ya está a punto de fallar, utilizando el análisis de elementos finitos para evaluar el comportamiento de la fractura, sin embargo, también es esencial analizar las etapas anteriores para prever la vida útil restante y evaluar factores de corrosión del ambiente. Las variables externas incluyen radiación UV, temperatura y humedad, mientras que las variables internas son propiedades mecánicas del material. La degradación esperada se representa como una función del tiempo y estas variables. Se calcula el esfuerzo máximo aceptable y la longitud máxima permisible de la grieta para determinar si el componente es seguro. Se presentan algunos casos de estudio en materiales ferrosos AISI 4140, donde se midió la degradación en la periferia de una probeta y se calculó la tendencia de la degradación, así como el estudio del análisis del elemento finito, para poder identificar los procesos principales máximos que rodean a los límites de la grieta
Biosíntesis fúngica de nanopartículas basadas en lantánidos para aplicaciones en sector salud: una Revisión
Authors: Armenta Silvia , Armenta Jaime Erika , Galdámez Martínez Andrés , Rivera Román Ángeles Alitzel , Rodríguez Lugo Ventura , Arce Cervantes Oscar
Published: October 2024

Este artículo explora el uso de los hongos en la síntesis de nanomateriales basados en lantánidos, demostrando su aplicación innovadora como agentes fúngicos en la nanobiotecnología. Se realiza una revisión en la que se examina el papel crucial de los hongos en la obtención de nanoestructuras basadas en lantánidos y sus aplicaciones potenciales en biotecnología. También se analiza cómo estos materiales se utilizan en recubrimientos antimicrobianos, agentes de etiquetado y la biorecuperación de lantánidos a partir de residuos industriales y recursos minerales utilizando organismos fúngicos. Además, hace hincapié en la importancia de los métodos de síntesis respetuosos con el medio ambiente y la evaluación de la toxicidad de estos materiales para ambos entornos y organismos. Este trabajo destaca la importancia de la investigación interdisciplinaria que une la biología fúngica con la nanotecnología para un futuro más sostenible.
Efecto sinérgico de tiosulfato de sodio y glicina en la lixiviación de plata, utilizando peróxido de hidrógeno como oxidante y etilenglicol, en una muestra polimetálica de Zimapán: influencia de la temperatura
Authors: Huazo Barrios Juan Miguel , Cisneros Flores Gabriel , Juárez Tapia Julio César , Teja Ruíz Aislinn Michelle , Hernández Ortiz Oscar Javier , Legorreta García Felipe
Published: October 2024

La extracción de metales preciosos como la plata (Ag) de concentrados y otras fuentes secundarias ha alcanzado con el uso de sistemas ecoamigables como el de tiosulfato - glicina, una alternativa viable a la lixiviación con cianuro. Este estudio evalúa la interacción entre el tiosulfato de sodio y la glicina a través de un análisis espectroscópico de Uv - vis, mostrando un cambio de absorbancia en una proporción 1:0.5. El concentrado de cobre proveniente del distrito minero de Zimapán fue analizado química y mineralógicamente, confirmando su composición polimetálica. Experimentos de lixiviación de Ag a distintas temperaturas demostraron que el sistema Na2S2O3 – gly – H2O2 – EG logró disolver el 80% de Ag en 90 minutos a 25 °C.  La curva de disolución indica que la interacción entre tiosulfato y glicina cataliza el proceso de lixiviación, posiblemente potenciada por la presencia de iones metálicos en la muestra, que podrían actuar como catalizadores adicionales
Ocurrencia de lepidolita con (Li) en la Formación Atotonilco el Grande, en el estado de Hidalgo.
Authors: Vera Morales Betzabé Andrea , Hernández Ávila Juan , Salinas Rodríguez Eleazar , Cerecedo Sáenz Eduardo , Flores Badillo Javier , Aquino Torres Eliazar
Published: October 2024

En este trabajo se realizó la caracterización de un mineral de lepidolita con contenidos de litio. Dado que el litio es un mineral estratégico, es importante establecer posibles fuentes minerales alternas de litio que permitan desarrollar tecnologías tanto, para su prospección y su posterior extracción. A partir de técnicas analíticas se determinó que se trata de una mineral de lepidolita con PDF [96-900-0629⦌, los análisis de XPS revelaron la presencia de litio con 0.3%, entre otros elementos como Si, C, F, O, Mg. Se puede concluir que la ocurrencia de lepidolita corresponde a una edad de K/Ar 2.56 Ma del Plioceno, como resultado de actividad de fluidos hidrotermales de origen magmático.