bluuebunny/crossref_metadata_2025 huggingface dataset:
Host Genetic Background Effect on Body Weight Changes Influenced by Smad4 Knockout Using Collaborative Cross Mouse Population
Authors: Qahaz Nayrouz , Lone Iqbal M. , Ghnaim Aya , Khadeja Aya , Zohud Osayd , Bennun Nadav , Nashef Aysar , Abu El-Naaj Imad , Iraqi Fuad A.
Published: September 2023

Background: Obesity and its attendant conditions have become major health problems worldwide and is currently ranked as the fifth most common leading cause of death globally. Complex environmental and genetic factors are the cause of the current obesity epidemic. Diet, lifestyle, chemical exposures, and other confounding factors are difficult to manage in humans. The mice model is helpful in researching genetics BW gain because genetic and environmental risk factors can be controlled in mice. Studies in mouse strains with various genetic backgrounds and established genetic structures provide unparalleled opportunities to find and analyze trait-related genomic loci. In this study, we used the Collaborative Cross (CC), a large panel of recombinant inbred mouse strains, to present a predictive study using CC mice SMAD4 knockout profiles to understand and effectively identify predisposition to body weight gain. Materials and Methods: Male C57Bl / 6J Smad4+/- mice were mated with female mice from 10 different CC lines to create F1 mice (Smad4+/- x CC). Body weight (BW) was measured weekly until week 16, then monthly until the end (week 48). The heritability H2 of the assessed traits was estimated and presented. Comparative analysis of various machine learning algorithms for predicting the BW changes and genotype of mice was conducted. Results and conclusions: Our data showed that the body weight records of F1 mice with different CC lines differed between wildtype and mutant Smad4 mice during the experiment. Genetic background affects weight gain and some lines gained more weight in the presence of Smad4 knockout, while others gained less, but in general, the mutation caused overweight mice, except for a few lines. In both control and mutant groups, female %BW had a higher heritability H2 value than males. Additionally, both sexes with wildtype genotypes showed higher heritability values than the mutant group. Logistic Regression provides the most accurate mouse genotype predictions using machine learning. We plan to validate the proposed method on more CC lines and mice per line to expand machine learning for BW prediction.
Assessing Functional Capacity in ME/CFS: A Patient Informed Questionnaire
Authors: Sommerfelt Kristian , Schei Trude , Seton Katharine A , Carding Simon R
Published: September 2023

: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is an acquired disease with significant morbidity that affects both children and adults. Effective tools to assess functional capacity (FC) are severely lacking which has significant consequences for timely diagnosis, assessments for patient disability benefits and assessing the impact and effectiveness of interventions. In interventional research the inability to assess FC can result in an incomplete assessment of the potential effect of the intervention. Specifically of concern is that if an intervention is effective in reducing symptom load, patients may increase their activity level to reach a pre-intervention symptom load. Thus, if FC is not accurately assessed, beneficial treatment outcomes may be missed. To address this issue, using extensive, repeated patient feedback we have developed a new questionnaire, FUNCAP, to achieve optimal FC assessment in ME/CFS patients. The questionnaire covers eight domains and activity types: A. Personal hygiene / basic functions, B. Walking / movement, C. Being upright, D. Activities in the home, E. Communication, F. Activities outside the home, G. Reactions to light and sound, and H. Concentration. Through five rounds of anonymous web-based surveys and a further test - retest validation round, two versions of the questionnaire were developed; a longer version comprising 55 questions (FUNCAP55) to improve diagnostic and disability benefit/ insurance FC assessments and a shorter version (FUNCAP27) for interventional research and less extensive FC assessments. FUNCAP may also be useful in other conditions where fatigue and PEM is present, such as Long Covid.
The Rate of Entropy Production in Biophysical-Chemical Systems
Authors: Nieto-Villar J.M. , Mansilla R.
Published: September 2023

An overview of the link between nonequilibrium thermodynamics and complexity theory is offered. It is shown how the rate of entropy production can be quantified through the spectrum of the Lyapunov exponents. It was shown how the entropy production per unit of time meets the necessary and sufficient conditions to be a Lyapunov function and constitutes per se an extremal principle. The entropy production fractal dimension conjecture was established. It is shown how the rate of entropy production as a non-extremal criterion represents an alternative way of sensitivity analysis of differential equations. Finally, an extension to biophysical-chemical systems, on the one hand, the use of the dissipation function is shown, as a thermodynamic potential out of equilibrium, in the characterization of biological phase transitions. On the other hand, it was evidenced how the rate of entropy production represents a physical quantity to evaluate the complexity and robustness of cancer.
Resistance to Plant Parasites in Tomato Is Induced by Soil Enrichment with Specific Bacterial and Fungal Rhizosphere Microbiome
Authors: Molinari Sergio , Leonetti Paola
Published: September 2023

Commercial formulates of beneficial microbes have been used to enrich the rhizosphere microbiome of tomato plants grown in pots located in a glasshouse. These plants have been subjected to attacks by soil-borne parasites, such as root-knot nematodes (RKNs), and herbivores, such as the miner insect Tuta absoluta. The development of both parasites and the symptoms of their parasitism were restricted in these plants with respect to plants left untreated. A mixture, named in the text as Myco, containing plant growth promoting rhizobacteria (PGPR), opportunistic biocontrol fungi (BCF), and arbuscular mycorrhizal fungi (AMF) was more effective in limiting pest damages than a formulate containing the sole AMF (Ozor). Therefore, Myco-treated plants inoculated with RKNs were taken as a model to further study which biocontrol agent (BCA) was specifically responsible of plant immunization and the molecular pathways exploited to achieve such an immunization. The PGPR contained in Myco were not able to reduce nematode infection, rather, they worsened symptoms on plants, compared with those observed on untreated plants. When plants were treated with suspensions of Bacillus subtilis at concentrations similar to those provided with Myco and then inoculated with RKNs, infection was actually more severe than that on untreated plants. Therefore, it was argued that both BCF and AMFwere the microorganisms that, colonizing roots, synergistically stimulate plant immune system against RKNs. Beneficial fungi lowered the activities of the defense supporting enzymes endochitinases and β-1,3-glucanase to be able to colonize the roots. However, as early as three days after nematode inoculation, these enzyme activities, and the expression of the encoding pathogenesis related genes (PR-2, PR-3) were found to be enhanced in roots with respect to not inoculated plants, thus indicating that plants had been primed against RKNs. Addition of paclobutrazol, which reduced salicylic acid (SA) levels in cells, and of diphenyliodonium chloride, which inhibits superoxides generation, completely abolished the repressive effect of Myco on nematode infection and presumably plant immune reaction. Inhibitors of copper enzymes and of the alternative cyanide-resistant respiration did not significantly alter resistance induction by Myco. When Myco-treated plants were subjected to a moderate water stress and inoculated with nematodes, they retained numbers of developed individuals in the roots similar to those present in regularly watered plants, in contrast to what occurred in roots of untreated stressed plants that hosted very few individuals because of poor nutrient availability.
An Emulsified Liquid Paraffin Formulation for Functional Constipation: Pharmacokinetics of Vitamins K1, D3, A, and E in a Rat Model
Authors: Perez Agudo Federico , Mannila Janne , Rinne Valtteri , Kallio Elina , Moilanen Ville
Published: September 2023

The pharmacokinetic profile of fat-soluble vitamins A, E, K1, and D3 co-administered with liquid paraffin or water in an experimental rat model was investigated. Animals received a solution of the four vitamins orally through a probe, followed 10 minutes later by the administration of either the liquid paraffin product dissolved in water (Emuliquen Simple®) or water (control). Vitamin formulations were 20, 50, 0.30 and 0.10 mg/kg for vitamins A, E, K1, and D3, respectively. Blood samples were collected before dosing and at 0.17, 1, 2, 4, 8, and 24 hours post-dosing. Vitamin concentrations were quantified by liquid chromatography coupled with mass spectrometry. No relevant differences in the absorption of vitamins in terms of AUC0-last (area under the curve up to the last measurable concentration) or Cmax in the absence or presence of co-administration of the liquid paraffin product were observed. The difference of these parameters between the treatment groups for all vitamins was in the range of bioequivalence (≤ 20%). The liquid paraffin-based laxative product did not interfere with the absorption of vitamins A, E, K1, and D3 that are ingested in the diet, which is clinically relevant due to the high prevalence of functional constipation in children and adults.
Effectiveness and Applications of an Antimicrobial Biopolymer Compatible with Additive Manufacturing
Authors: Zuniga Jorge M. , Evenson Alex , D'Ovidio Andrew
Published: September 2023

Background: Advances in additive manufacturing and the development of antimicrobial biopolymers facilitate the production of critical medical devices with strong and safe biocidal properties. The purpose of this study was to assess the antimicrobial efficacy, safety, and longevity of a polylactic acid-based biopolymer supplemented with a copper-based composite additive. Methods: An antimicrobial polylactic acid-based biopolymer was tested against several inoculants including Staphylococcus Aureus, MRSA, E. coli, Listeria, HCoV-229E (a SARS-CoV-2 surrogate), and HIV-1. Material safety was evaluated according to international testing standards for in vitro cytotoxicity. Results: The main findings of the present investigation showed a strong and long-lasting biocidal effect of a polylactic acid-based biopolymer embedded with a copper-based composite additive against Staphylococcus Aureus, MRSA, E. coli, Listeria, HCoV-229E (a SARS-CoV-2 surrogate), and HIV-1. Furthermore, the cytotoxicity and safety assessment of the antimicrobial biopolymer was found to be “non-toxic” and safe for human skin contact. Conclusions: The present investigation showed that the antimicrobial biopolymer exhibits strong and long-lasting biocidal properties against an array of viral and bacterial inoculants.
Protoplasmic Perivascular Astrocytes Play a Crucial Role in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus
Authors: Hayden Melvin R.
Published: September 2023

Abstract: Astrocytes (ACs) are the most abundant human cell in the brain and importantly, are the master connecting and communicating cells that provide structural and functional support of brain cells at all levels of organization. Further, they are recognized to be the guardians and housekeepers of the brain. Protoplasmic perivascular astrocyte endfeet and their basal lamina form the delimiting outermost barrier (glia limitans) of the perivascular spaces in postcapillary venules and are important for the clearance of metabolic waste and comprise the glymphatic system, which is critically dependent on the proper waste removal by the pvACef polarized aquaporin 4 water channels. Also, the protoplasmic perisynaptic astrocyte endfeet (psACef) are important in cradling the neuronal synapses that serve to maintain homeostasis and serve a functional and supportive role for synaptic transmission. Enlarged perivascular spaces (EPVS) are emerging as important aberrant findings on magnetic resonance imaging (MRI) and associate with white matter hyperintensities, lacunes, aging, accepted to be biomarkers for cerebral small vessel disease, increased in obesity, metabolic syndrome, and type 2 diabetes. Knowledge is exponentially expanding regarding EPVS along with the glymphatic system, since EPVS are closely associated with impaired glymphatic function and waste removal from the brain to the cerebrospinal fluid and systemic circulation. This review intends to focus on how the pvACef play a crucial role in the development of EPVS.
Distributed Generation Control Using Ripple Signaling and an Innovative Communication Gateway
Authors: Boutsiadis Evangelos , Pasialis Nikolaos , Lettas Nikolaos , Tsiamitros Dimitrios , Stimoniaris Dimitrios
Published: September 2023

Remote distributed generation control and demand response is nowadays a basic need, especially for the Distributed Network Operators (DNOs). The integration of Renewable Energy Sources (RES) with stochastic production characteristics into the grid in conjunction with the newly appeared stochastic demand consumers (i.e., electric vehicles) hardens the ef-forts of the DNOs to keep the grid’s operation within safe limits and prevent cascading black-outs while staying in compliance with the SAIDI and SAIFI indices during maintenance and re-pair operations. Taking also under consideration the aging of the existing grid infrastructure, making it year by year more prone to failure, it is yet of great significance for the DNOs to have access to real-time feedback from grid’s infrastructure, fast, with low-cost upgrade interventions, easily deployed on the field and with fast response potential, in order to be able to perform real-time grid management (RTGM). In this article, we describe the architecture, development and deployment of a hybrid real-time control system of distributed generation (DG) units, which has the potential to be applied easily to DNO’s substations, RES plants and consumers (i.e. electric vehicles’ charging stations), that combines a low-cost minimum intervention into the electricity grid and its components and eliminates all communication interoperability problems between the different vendors’ installed electrical equipment.
Worldwide Human Cytomegalovirus Oncoprotection across Diverse Populations, Tumor Histologies and Age Groups: Paving the Way for Innovative Cancer Therapies
Authors: Jankovic Marko , Knezevic Tara , Jovanovic Tanja , Todorovic-Balint Milena , Djunic Irena , Mihaljevic Biljana , Knezevic Aleksandra
Published: September 2023

The oncogenicity of the human cytomegalovirus (CMV) is debated to this day. In recent years, mounting evidence addresses an anti-cancer effect via T cell-mediated CMV-targeted tumor de-struction. However, the data mostly comes from single-center studies and in vitro experiments. Broad geographic coverage is required to offer a global perspective. This study examined the correlation between country-specific CMV seroprevalence (n=73) and age-standardized inci-dence rates for 34 tumors using data obtained from the International Agency for Research on Cancer of the World Health Organization. The association between CMV and cancer incidences in 10-year age increments was also analyzed. The study revealed a worldwide inverse correlation between CMV seroprevalence and incidences of 88.2% tumors. Notably, this inverse link persists for all cancers combined (Spearman’s ρ= -0.732, p= 0.001). An antithetical and significant correlation is also observed in particular age groups for the vast majority of tumors. Our results corroborate the conclusions of previous studies and indicate that this phenomenon holds true on a global scale. It applies to a wide spectrum of cancer histologies, suggesting a common under-lying mechanism – CMV-stimulated T cell tumor targeting. Although these results further advance the notion of CMV-based therapies, further in-depth investigation of host-virus interactions is warranted.
Cocopeat Perlite Mixture as an Alternative for Rooted Cuttings Growth Medium of Impatiens hawkeri x platypetala in Indonesia
Authors: Shintiavira Herni , Dewanti Minangsari , Rachmawati Fitri , Nurlaeni Yati , Nurdina Dani , Sadli Sadli , Ariyantika Safani , Kartikaningrum Suskandari
Published: September 2023

Impatiens hawkeri x platypetala rooted cuttings are typically cultivated using rice husks as a substrate. However, due to the poor water-holding capacity of this medium, Impatiens grows slowly in this environment. A viable alternative is the cocopeat perlite mixture which has a better water-holding capacity compared to the rice husk. Currently, there is no sufficient information available regarding the best growth medium to improve the quality of I. hawkeri x platypetala rooted cuttings in Indonesia. Therefore, this study aimed to obtain the best medium for quality rooted cuttings I. hawkeri x platypetala. The method employed was a randomized complete block design with two factors. The first factor was the Impatiens varieties consisting of Impala Agrihorti, Imadata Agrihorti, and Lavender, while the second was the growth medium, comprised of four levels namely rice husk (control), as well as a mixture of cocopeat with 3%, 5% and 8% perlite. The result showed that there was no interaction between varieties and growth medium. The mixture of 3% perlite in cocopeat exhibited better outcomes compared to other treatments. This medium increased the number and length of roots, stem diameter, plant height, leaves thickness, leaves number and survival rate. Therefore, the addition of 3% perlite in cocopeat could replace the rice husk as a rooted cutting growth medium for I. hawkeri x platypetala.
The Potential of Rhizophagus intraradices, Bacillus thuringiensis Bt BMKP and Silica for Anthracnose Disease Control in Shallot
Authors: Amallia Rizky , Suryanti Suryanti , Joko Tri
Published: September 2023

Anthracnose caused by Colletotrichum gloeosporioides is a prevalent disease that poses a significant threat to shallot production in Indonesia. To mitigate this issue, the use of biological agents presents an alternative for disease control, reducing the inherent risks associated with the use of chemical pesticides. Therefore, this study aimed to determine the potentiality and mechanism of the biological agents (Rhizophagus intraradices and Bacillus thuringiensis) combined with silica. These agents were evaluated both individually and in combination to suppress the development of anthracnose in Tajuk variety shallot. The study was conducted in the laboratory and greenhouse, arranged in a completely randomized design with six treatments and three replications. The ability to suppress pathogenic fungi was determined based on in vitro antagonism tests of B. thuringiensis, disease severity, area under disease progress curve (AUDPC), plant height, number of leaves, number of tillers and the percentage of mycorrhizal fungal infections. Furthermore, the mycorrhizal infection on plant roots was observed using staining methods. The results showed that the Bt BMKP isolate was included in the B. thuringiensis strain RC9 group with the capacity to inhibit C. gloeosporioides in vitro by 18.88%. The combination treatment of R. intraradices, B. thuringiensis and silica reduced infection from anthracnose by 15.52% compared with control. These three treatments also significantly increased the agronomic performance of shallot up to six weeks after planting compared to control and other treatments.
Special Issue on ICoE Taipei Integrated Research on Disaster Risk
Authors: Lee Jian-Cheng , Chang Chung-Pai , Hayashi Haruo , Chen Hongey
Published: September 2023

Established in 2010 as an integrated research program for disaster risk reduction, the IRDR ICoE Taipei is co-sponsored by the International Science Council (ISC) and the United Nations Office for Disaster Risk Reduction (UNDRR). In the past decade, the IRDR ICoE Taipei has received hundreds of participants around the world to the more than a dozen international training workshops (AI, Advanced Institute) it has organized. These workshops focused mostly on the capacity building program for disaster risk reduction. Bearing this in mind, one important motivation for this Special Issue was to encourage the participants of each Advanced Institute, in particular those who were awarded Seed Grants to conduct one-year projects following each workshop, to publish the results of their studies on the topics related to disaster risk reduction.

In this Special Issue, the first paper provides a brief review of the capacity building program of the IRDR ICoE Taipei, followed by three research articles. Viola van Onselen and her co-workers in Taiwan present a methodology of strategies of ecosystem-based disaster risk reduction, with several case studies in coastal environments of Taiwan. Shyamli Singh of India proposes an integrated system for sustainable rice economics linking from farm to market, a case study on one of the largest rice production fields on the Indo-Gangetic plain. From the engineering perspective, Wen-Yi Huang and his colleagues in Taiwan and Australia present a paper dealing with the reinforcement of soil walls to prevent geohazards on the roads.

This is the first special issue produced as a collaboration between the IRDR ICoE Taipei and the JDR, with great support from the National Science and Technology Center for Disaster Reduction (NCDR) and Academia Sinica of Taiwan. We hope there will be more Special Issues to come in the next few years.
Assessment of Ecosystem-Based Disaster Risk Reduction Strategies in Coastal Environments of Taiwan
Authors: Onselen Viola van , Bayrak Mucahid Mustafa , Lin Tsung-Yi
Published: September 2023

Taiwan’s rapid economic and industrial growth has put enormous pressure on its natural environment. This is especially visible in the coastal zone, where risks such as sea-level rise, coastal erosion, land subsidence, and flooding threaten the already vulnerable ecosystems. Ecosystem-based disaster risk reduction (Eco-DRR) is a management strategy that uses ecosystems to reduce disaster risks. While this type of strategy is promoted in the ‘Taiwan Coastal Zone Management Act’ (TCZMA), there is still a lack of data on the implementation of Eco-DRR methods in Taiwan. This study examines papers on policy analyses of the TCZMA, and five main barriers for implementation of Eco-DRR in Taiwan are identified. Subsequently, in order to assess Eco-DRR strategies in the coastal zone of Taiwan, case studies and evaluation data on ecosystem-based management strategies were assembled and evaluated. The results of this study show that initial strategies to plant mangroves for reduction of wave energy have not always been successful; in certain areas they were removed again due to invasiveness in endemic wetland ecosystems. Moreover, artificially building sand dunes can have negative side effects, like oversteepening of the dune profile or deteriorating the natural dune dynamics. To address and tackle aforementioned challenges, a novel framework is introduced for improved uptake of Eco-DRR in Taiwan and beyond, and suggestions for future strategies are proposed.
Consideration for Solving Problems Related to Volcanic Disaster Prevention by Real-Time Grasping of Climber Movement
Authors: Miyagi Yousuke , Yoshimori Kazushiro , Kaneta Shigeharu , Usuda Yuichiro
Published: September 2023

We carry out experiments to grasp the movement of climbers as well as an experiment to share the disaster situation with related organizations in real time, at Nasudake in 2020 and Ontakesan in 2022. In the experiments, small beacons are distributed to many climbers, and their movements are detected by receivers installed on mountain trails in advance. We build an online viewer to visualize the monitoring results on a web map in real time, and share them with the related organizations, and exchange opinions with them about the use of the acquired data for disaster prevention. Based on the results of the experiments, we consider how to solve problems related to volcanic disaster prevention. It is shown that the systems used in the experiments leads to solutions to problems related to volcanic disaster prevention during not only disasters but also normal times, such as updating drills and revising evacuation plans.
Public Perceptions of the Aral Sea Disaster in Uzbekistan
Authors: Lloyd Steven , Nakamura Tetsuya , Masuda Satoru
Published: September 2023

This study focuses on how the Uzbek public perceives the Aral Sea disaster, the role of the government, the UN, and other agencies, and their overall attitude toward the future of the region. This research is based on an online survey of 599 people across Uzbekistan. The results show that the participants are largely supportive of government and optimistic for the future of the Aral Sea region, despite also being concerned for its environment. The role of traditional and social media plays a crucial role in informing and shaping people’s opinions. A sense of inclusion and representation within the decision-making process led to increased government support amongst the attitudes of the participants.
Can Green Market Orientation Improve MSME Marketing Performance Through Organizational Ambidexterity?
Authors: Bogy Febriatmoko  , Widya Prananta  , Angga Pandu Wijaya
Published: September 2023

There are environmental issues in many nations, including Indonesia. The preservation of the environment must continue to be the focus of sustainable national development. Small, micro, and medium-sized enterprises (MSMEs) are among the commercial entities that play a significant role in national growth. This study's main objective is to ascertain how innovation capacity and a green market orientation affect MSMEs' marketing success. 117 MSMEs in the city of Semarang make up the study's sample. The process involves using Smart PLS to analyze both the outer and inner models together with any intervening factors. Organizational Ambidexterity, Green Market Orientation, Innovation Capability, and Marketing Performance are the variables used in this study. The findings of this study indicate that Organizational Ambidexterity, Green Market Orientation, and Innovation Capability are all variables that have an impact on Marketing Performance. Organizational Ambidexterity also has an impact on Marketing Performance to a lesser extent. Then simultaneously show that Green Market Orientation and Innovation capability affect Marketing Performance through Organizational Ambidexterity. Only Innovation Capability on Marketing Performance has no effect. The novelty in this study is an environmental issue that is associated with marketing performance.
INFRASTRUCTURE FACILITY NEEDS ANALYSIS CITY PARK IN THE NEW NORMAL ERA
Authors: Hargianti Mita , Nasution Nasution , Hidayat Husnul
Published: September 2023

City parks are again crowded with people after COVID-19 to play, exercise and recreation, and Adipura Muara Enim Park is no exception. The Covid-19 pandemic is not certain to end. For this reason, the facilities available in city parks in the new normal era need to be conditioned so that they can provide optimal services and can support the government's efforts in handling COVID-19. The aim of the research is to analyze the need for infrastructure facilities and get the "level of service" (LOS). The research used a descriptive survey data collection method in the form of observing physical settings, functional aspects and similar research theories and then distributing questionnaires with several variables, namely the level of service facilities, level of activity level, significance and level of ease of achievement. Attitudes were assessed using a Likert scale and the "level of service" (LOS) analysis method. The results showed that the level of service at Adipura Muara Enim Park was F (< 5), that is, there was an accumulation of user activity due to the uneven distribution of facilities. It is necessary to add and adjust the facility design to meet the new normal criteria, including: the addition of an outdoor gym, guard post, information media boards, hand washing facilities, body temperature measuring device, pavement material pattern as a spacer, single seats, vegetation as a barrier between facility.
EVALUATION OF TECHNOLOGY AND ENGINEERING VOCATIONAL SCHOOL STUDENTS IMPLEMENTATION: SYSTEMATIC LITERATURE REVIEW
Authors: Endah Sri Wahyuni  , Arthur Riyan , Soeprijanto
Published: September 2023

Implementation of Field Work Practice (FWP) for Vocational High School (VHS) students is one of the programs planned as a means for students to improve competence in both soft skills and hard skills, besides that by carrying out FWP students get learning and training bythe world of work. Every student supervisor or teacher has difficulty evaluating the results of street vendors, due to the lack of references obtained by student supervisors in implementing the street vendors program at VHS. This study aims to identify and analyze various approaches and evaluation models that have been used in the implementation of street vendors in VHS students. This research method uses a systematic literature review (SLR) with a descriptive explanatory type of research to gain a comprehensive understanding of the evaluation of the street vendors program implementation. This study found 50 articles on the topic of street vendors from various disciplines, but 15 research articles that were appropriate to the topic of Technology and Engineering came from various literary sources or based on the database found on Google Scholar. This study produced three evaluation models, namely the Context, Input, Process, and Product (CIPP) model with 15 articles, the discrepancy model with 3 articles, and the goal-oriented model with 2 articles. The contribution of this research is expected to increase understanding of the evaluation of the implementation of the street vendors program for VHS students and to lay a strong basis for the development of better evaluations in the future.
PERFORMANCE ANALYSIS OF HORIZONTAL IRREGULAR BUILDINGS BASED ON RESPONS SPEKCTRUM AND TIME HISTORY METHODE
Authors: Simbolon Steffy Catharina Rebeccha , Tampubolon Sudarno P. , Mulyani Agnes Sri
Published: September 2023

Indonesia is geographically located in the Pacific Ring of Fire, Especially on Java Island, which has the densest infrastructure and population and is located between the Indo-Australian plate and the Eurasian plate, causing this area to have many active volcanoes and has a high potential for earthquakes. Therefore, it is necessary to pay the planned earthquake load in planning the building structure design to minimize losses due to the earthquake. This study aims to determine the structure's performance against safeguards, deviations between levels, and structural stability limits against earthquake loads and to review horizontal structural irregularities based on SNI 1726: 2019 regulations in existing buildings at the Simpang Temu MRT Dukuh Atas Jakarta Building. The analysis process was carried out by 3D building modeling using the ETABS software program, analysis based on time history and spectrum response. Time History analysis uses recorded earthquakes of Kobe Japan, ChiChi Taiwan, and El Centro which match the earthquake response spectrum, the results of the analysis based on the program were carried out to compare the two methods used. Based on the results of the analysis, the building is classified into horizontal irregularities with excessive torque ratio > 1.4, average displacement value from the 2nd to 12th floor in the horizontal direction X exceeds the drift value limit. The results of the instability limit for structural stability against displacement based on the P-Delta effect still meet the structural stability limits so it can be stated that the structure is stable and safe.
PERFORMANCE OF MASONRY BRICK WITH CALCIUM HYDROXIDE AS MORTAR
Authors: Darmono Darmono , Ma’arif Faqih , Widodo Slamet , Nugroho Maris Setyo
Published: September 2023

This study aims to determine the shear strength and flexural strength of red brick masonry, determine the effective thickness of calcium hydroxide mortar with a mixture ratio of 1Kp:2Ps, and determine the failure pattern of red brick masonry due to the load received during the direct shear strength test and flexural strength test. The research was conducted by experimental method. The tests carried out were the direct shear and flexural strength tests. Variation of successive mortar thickness of 10mm, 15mm, and 20mm. The test object is 18 (eighteen), the thickness variation consists of 3 test objects. Data analysis used descriptive quantitative by finding the average value of the shear strength and flexural strength. Based on the test results, the average compressive strength and splitting tensile strength of the mortar were 0.613 MPa, 0.0414 MPa. The average shear strength with a 10mm; 15mm; and 20mm is 0.025 MPa; 0.020 MPa; and 0.016 MPa, respectively. The flexural strength of mortar thickness with 10mm, 15mm, and 20mm are 0.034 MPa; 0.045 MPa; and 0.041 MPa, , respectively. In the masonry shear test, the effective thickness of the mortar was found at 10mm with a maximum shear strength of 0.025 MPa, while in the flexural test, the effective thickness of the mortar was found at a thickness of 15mm with 0.045 MPa. The pattern of failure in red masonry's shear strength and flexural strength tests is the mortar failure.
Penguatan Analisis Lingkungan Internal (ALI) dan Analisis Lingkungan Eksternal (ALE) di Lembaga Pendidikan Islam dalam Menghadapi Era Disrupsi
Authors: Mihdad Mahda Fiqia Ahmad , Chotimah Chusnul , Sulistyorini
Published: September 2023

This study aims to describe analysis of internal and external environment of SDIT Al-Azhaar in facing the era of disruption, in order to survive. The method used in this research is descriptive qualitative method. Data collection techniques using semi-structured interviews, semi-participant observation, and documentation. The analysis techniques used include data collection, data condensation, data presentation, and drawing conclusions. The results of this study indicate: 1) SDIT's internal environment analysis consists of competency aspects in the form of quality educational institutions that are already good, core competencies in the form of SDIT Al-Azhaar's contribution to Trenggalek district by sending students to competitions, resource aspects dominated by teachers with graduates S1, and BOS funding which can be said to be large enough to optimize existing learning activities, 2) external environmental analysis, namely SDIT Al-Azhaar always seeks to collaborate with existing stakeholders, establish cooperation with external organizations, have a role and support local government towards SDIT Al-Azhaar in increasing school quality competition, 3) efforts to strengthen the internal environment are carried out at SDIT Al-Azhaar by utilizing digital-based learning media, each educator is given insight regarding the use of technology, communicating with guardians using smartphone media, 4) strengthening The external environment is carried out by holding periodic socialization with the community and stakeholders, using media for promotional activities and updating activities within the school scope, using technology in the facilities and infrastructure used. This strengthening effort was carried out as a preparation for students to be able to face the era of disruption.
Marketing Mix Jasa Pendidikan Sebagai Strategi Peningkatan Kuantitas Peserta Didik di MA Muhammadiyah 5 Sidoharjo
Authors: Pratiwi Dian , Inayati Awalul
Published: September 2023

Marketing mix as a marketing tool must be considered and managed properly so that marketing in educational institutions runs successfully. This study aims to analyze (1) the application of marketing education services at MA Muhammadiyah 5 Sidoharjo; (2) the steps of marketing mix education services as a strategy to increase the quantity of students at MA Muhammadiyah 5 Sidoharjo; and (3) increasing the quantity of students at MA Muhammadiyah 5 Sidoharjo. The research was designed using qualitative research methods that emphasize understanding of problems in social life based on real conditions or natural settings that are holistic, complex and detailed. Type of case study research. Data collection is done through in-depth interview procedures, observation, and documentation. Informants or sources in this study came from principals, educators, education personnel, students, and student guardians. Then the research data were analyzed using the Miles and Huberman analysis model, namely data condensation, data presentation, and conclusion drawing. Based on the results of data analysis, it was found that (1) the application of marketing of educational services that should be considered and schools should be able to make appropriate marketing strategies more specifically schools in managing marketing of their educational services must do analysis, organization, planning, control, (2) the steps of the marketing mix strategy applied at MA Muhammadiyah 5 Sidoharjo some of which are no payment for building fees and making payment options, located in a strategic place then they use social media as a tool for disseminating information in marketing activities. (3) there was an increase in the number of students at MA Muhammadiyah 5 Sidoharjo after experiencing a very drastic decline in 2019 where the incoming students were less than 10 students, and with a new strategy by carrying out the theme of natural schools in 2020 they experienced an increase in the number of students, namely students who entered 14 students.
Paradigma dan Esensi Manajemen Hubungan Masyarakat dalam Pendidikan Islam
Authors: Iffah Okta Afiana  , Alfiana Ghani  , Mardiyah
Published: September 2023

This article aims to examine a scientific theoretical model related to society, human thinking activities, leadership or management and the nature of society in the perspective of Islamic education. By using the research method library research (library research) this research was carried out by utilizing the literature from previous researchers. The analysis technique used is data or content analysis techniques. While the data collection instrument is carried out through reading activities in depth to reveal the essence of the various data collected. Data or content analysis is carried out to obtain valid inferences and can be re-examined in context. From the research it was found that public relations management can increase community empowerment. Through this empowerment, it makes the community have a community that has resilience in various sectors of life by making the public relations paradigm a reference in socializing. There needs to be a separate approach to prevent a misunderstanding between individuals and others. While the basic essence of public relations management is taken from the teachings or values ??of Quran and hadith.
Responses of three species of microalgae to the presence of antibiotics commonly found in wastewater
Authors: Frascaroli Gabriele
Published: September 2023

The study evaluated the reactions of three types of microalgae to seven antibiotics commonly detected in wastewater. It examined growth patterns, pigment production, alterations in the media's pH, and the elimination of both nutrients and antibiotics. The findings from this investigation have been summarised in a schematic presentation of the data.
Radiomics Prediction Models of Left Atrial Appendage Hypercoagulability Based on Machine Learning Algorithms: An Exploration about Cardiac Computed Tomography Angiography Imaging
Authors: Wang Hongsen , Ge Lan , Zhou Hang , Lu Xu , Yu Zhe , Peng Peng , Wang Xinyan , Liu Ao , Chen Tao , Guo Jun , Chen Yundai
Published: September 2023

Background: Transesophageal echocardiography(TEE) is the standard method for diagnosing left atrial appendage (LAA) hypercoagulability in patients with atrial fibrillation (AF), which means LAA thrombus/sludge, dense spontaneous echo contrastand slow LAA blood flow velocity (<0.25 m/s). Based on machine learning algorithms, cardiac computed tomography angiography (CCTA) radiomics features were adopted to construct prediction models and explore a suitable approach for diagnosing LAA hypercoagulability and adjusting anticoagulation.
Methods: This study included 652 patients with non-valvular AF. The univariate analysis were used to select meaningful clinical characteristics to predict LAA hypercoagulability. Then 3D Slicer software were adopted to extract radiomics features from CCTA imaging. The radiomics score was calculated using the least absolute shrinkage and selection operator logistic regression analysis to predict LAA hypercoagulability. We then combined clinical characteristics and radiomics scores to construct a nomogram model. Finally, we got prediction models based on machine learning algorithms and logistic regression separately.
Results: The area under the receiver operating characteristic curve of radiomics score was 0.8449 in the training set and 0.7998 in the validation set. The nomogram model had a concordance index of 0.838. The final machine-learning based prediction models had good performances (best f1 score = 0.85).
Conclusion:Radiomics features of long maximum diameter and high uniformity of Hounsfield unit in left atrial are significant predictors of the hypercoagulable state in LAA, with better predictive efficacy than clinical characteristics. Our combined models based on machine learning are reliable for hypercoagulable state screening and anticoagulation adjustment.
AN ANALYSIS OF THE LINGUISTIC COMPETENCE OF MORPHOLOGY TEACHING ON YOUTUBE VIDEO SERIES
Authors: Maya Lailatul , Dewanti Ratna , Suseno Muchlas
Published: September 2023

Linguistic competence has had a significant influence on English language teaching. Linguistic competence is largely concerned with a notion shared by language teachers and learners when using language knowledge in real performance. English teachers are expected to have this competency. The present study aimed to examine linguistic competence in morphology teaching, which was demonstrated by an English teacher. The morphology teaching was sourced from a series of YouTube videos which were broadcast by a teacher on a Youtube channel. This study was carried out by analyzing the linguistic competence of the teacher in each video by analogizing the teacher’s knowledge with the theory from the linguistics book written by some experts. The selected books which were used to analyze were: “How English Works, A Linguistic Introduction” (Curzan & Adams, 2012); “Linguistics, An Introduction” (Radford et al., 2009); and “Contemporary Linguistic Analysis, An Introduction” (O’Grady & Archibald, 2016). The study’s findings revealed that the teacher had sufficient linguistic competence while delivering the course. The findings also assisted in recognizing that linguistic competence is a significant part of the analysis in terms of how a teacher may remain competent while providing the course. In short, linguistics is considered valuable because it may increase teacher’s awareness of language, making the teacher more competent and, hence, a better language teacher.
IMPROVING STUDENTS’ READING COMPREHENSION THROUGH SQ5R METHODS: A DISTANCE LEARNING DURING THE PANDEMIC COVID-19
Authors: Al Halim M. Labib
Published: September 2023

The entry of the Covid-19 virus in Indonesia has had a major impact on the education sector. The teacher could use several strategies during the learning process to be able to achieve the learning objectives. This study aimed to optimize the use of the Survey, Question, Read, Recite, Record, Review, Reflect (SQ5R) method in teaching reading during online learning at SMPN 3 Lamongan. The researcher used action research with direct observation during the learning process. The results showed that the SQ5R method could improve students' reading comprehension. The minimum score obtained by students in the initial test was 45. This value increased up to 65 in the final test, which indicated that all students had reached the minimum passing criteria standard that had been set. Meanwhile, the observations showed that students were able to analyze visual information, predict content and improve their notes. Overall, it was evident that the SQ5R approach has a positive impact on students' reading comprehension.
ESP STUDENTS' ATTITUDES TOWARDS JAMBOARD: REVOLUTIONIZING SELF-INTRODUCTION IN THE DIGITAL AGE
Authors: Ningsih Fitria , Nikmah Lailatul
Published: September 2023

This study explores the use of Jamboard as a tool for revolutionizing self-introduction among English for Specific Purposes (ESP) students in the digital age. It examines ESP students' attitudes towards the use of Jamboard in enhancing their self-introduction skills through a mixed-method approach, using both quantitative and qualitative data collection methods. A survey questionnaire was administered to 131 ESP students. The study found that the respondents have a high perception of Jamboard's usefulness, ease of use, appearance, and interaction towards their self-introduction, with a mean score of 3.8. The technology was found to be user-friendly, easy to use, and helpful in presenting ideas and showcasing creativity. However, some students also encountered difficulties with Jamboard's usability and features. The recommendations include providing support and training for the effective use of digital tools like Jamboard and incorporating user-friendly features. These implications can inform educators and developers in promoting student engagement, creativity, and collaborative learning. Further research can explore the impact of Jamboard on student learning outcomes and their perceptions and use of digital tools in the classroom.
Community, Fellowship, Openness: Supporting Early Career Researchers through Open Educational Practices
Authors: Iniesto Francisco , Pitt  , Bossu Carina , Farrow Rob , Weller Martin
Published: September 2023

Open communities are an increasingly common feature of educational spaces. This article summarises the experience of a fellowship scheme for early career researchers in open education supported by The Global OER Graduate Network (GO-GN), an international network to support doctoral candidates. Nine fellows over a three-year period were supported to conduct six-month personal projects to facilitate their academic career development post-doctoral studies. The fellowship scheme was structured into three, annual cohorts between 2020 and 2022.

Results from qualitative surveys and interviews indicate a positive and meaningful impact of the scheme. A key aspect of this type of initiative is the support given by more experienced academics and peer fellows. The fellowship scheme enabled the sharing of research among other PhD students and early career researchers through regular webinars and to broader audiences at internationally recognised conferences.

The results of this paper are of potential interest to those supporting doctoral researchers and organisations interested in running similar fellowships or other support schemes for doctoral researchers or other stakeholder groups.