bluuebunny/crossref_metadata_2025 huggingface dataset:
General allometric equations and biomass allocation of Pinus massoniana trees on a regional scale in southern China
Authors: Xiang Wenhua , Liu Shaohui , Deng Xiangwen , Shen Aihua , Lei Xiangdong , Tian Dalun , Zhao Meifang , Peng Changhui
Published: April 2011

Applying allometric equations in combination with forest inventory data is an effective approach to use when qualifying forest biomass and carbon storage on a regional scale. The objectives of this study were to (1) develop general allometric tree component biomass equations and (2) investigate tree biomass allocation patterns for Pinus massoniana, a principal tree species native to southern China, by applying 197 samples across 20 site locations. The additive allometric equations utilized to compute stem, branch, needle, root, aboveground, and total tree biomass were developed by nonlinear seemingly unrelated regression. Results show that the relative proportion of stem biomass to tree biomass increased while the contribution of canopy biomass to tree biomass decreased as trees continued to grow through time. Total root biomass was a large biomass pool in itself, and its relative proportion to tree biomass exhibited a slight increase with tree growth. Although equations employing stem diameter at breast height (dbh) alone as a predictor could accurately predict stem, aboveground, root, and total tree biomass, they were poorly fitted to predict the canopy biomass component. The inclusion of the tree height (H) variable either slightly improved or did not in any way increase model fitness. Validation results demonstrate that these equations are suitable to estimate stem, aboveground, and total tree biomass across a broad range of P. massoniana stands on a regional scale.
Solubilization of Aromatic Hydrocarbons in Ethylene Oxide‐Propylene Oxide Triblock Micelles: Location of Solubilizate and its Effect on Micelle Size from 2D NMR and Scattering Techniques
Authors: Parekh Paresh , Singh Kulbir , Marangoni D. Gerrard , Aswal Vinod K. , Bahadur Pratap
Published: April 2011

The solubilization of benzene and toluene in micellar solutions and the effects on the micellization and micelle size of ethylene oxide‐propylene oxide triblock copolymers were investigated by dynamic light scattering (DLS), small angle neutron scattering (SANS), and 2D NMR spectroscopy. The copolymeric surfactants have the same size as the middle hydrophobic polypropylene oxide block (Mol. Wt. 3250) and varying polyethylene oxide end blocks (30, 40 and 50%). The solubilization and the properties of the micelles in the presence of the solubilizates were investigated; the results reveal that the more hydrophobic copolymer showed better solubilization. The cloud points of the copolymers decreased in the presence of oils; the depression in the cloud point is due to the formation of an electron donor–acceptor complex. DLS shows that the effect of benzene is dominated at high oil concentration. SANS data show that the micelles remain spherical in shape and that the micellar core size does not change with higher benzene concentration; observed changes in the low scattering vector region could be because of some small amount of benzene clusters formed at higher benzene concentration. Finally, the locus of solubilization of the oils in the copolymer micelles was determined via 2D NMR experiments. In all cases, significant nuclear Overhauser effect spectroscopy (NOESY) cross peaks were observed that appeared to correlate well with the expected loci of these solubilizates in micelles. Hence, the noninvasive NOESY technique provides important information on the location of the aromatic solubilizates in these copolymer micelles that depends on the structure of the oils.
Spermatogonial stem cells and in vitro spermatogenesis
Authors: Ogawa Takehiko
Published: April 2011

Spermatogonial stem cells (SSCs) provide the basis for the life‐long production of enormous numbers of sperm. The nature of these mysterious cells is being clarified. Although they were regarded to be mostly dormant, dividing rarely and remaining static in a niche, their rather dynamic behavior in the seminiferous tubules has been disclosed. The territories of each colony of SSCs can also quickly change in size. The development of a culture method for SSCs also shed light on their stable, but at the same time, fragile characteristics. In addition, an in vitro system for spermatogenesis was developed which can produce functional sperm from SSCs. These new developments will contribute to reproductive medicine.
Modulation of gene-specific epigenetic states and transcription by non-coding RNAs
Authors: Morris Kevin V.
Published: April 2011

Emerging evidence points to a role for long non-coding RNAs in the modulation of epigenetic states and transcription in human cells. New insights, using various forms of small non-coding RNAs, suggest that a mechanism of action is operative in human cells, which utilizes non-coding RNAs to direct epigenetic marks to homology containing loci resulting ultimately in the epigenetic-based modulation of gene transcription. Importantly, insights into this mechanism of action have allowed for certain target sequences, which are either actively involved in RNA mediated epigenetic regulation or targets for non-coding RNA based epigenetic regulation, to be selected. As such, it is now feasible to utilize small antisense RNAs to either epigenetically silence a gene expression or remove epigenetic silencing of endogenous non-coding RNAs and essentially turn on a gene expression. Knowledge of this emerging RNA-based epigenetic regulatory network and our ability to cognitively control gene expression has deep implications in the development of an entirely new area of pharmacopeia.
The Protective Effect of Marriage for Survival: A Review and Update
Authors: Rendall Michael S. , Weden Margaret M. , Favreault Melissa M. , Waldron Hilary
Published: April 2011

The theory that marriage has protective effects for survival has itself lived for more than 100 years since Durkheim’s groundbreaking study of suicide (Durkheim 1951 [1897]). Investigations of differences in this protective effect by gender, by age, and in contrast to different unmarried statuses, however, have yielded inconsistent conclusions. These investigations typically either use data in which marital status and other covariates are observed in cross-sectional surveys up to 10 years before mortality exposure, or use data from panel surveys with much smaller sample sizes. Their conclusions are usually not based on formal statistical tests of contrasts between men and women or between never-married, divorced/separated, and widowed statuses. Using large-scale pooled panel survey data linked to death registrations and earnings histories for U.S. men and women aged 25 and older, and with appropriate contrast tests, we find a consistent survival advantage for married over unmarried men and women, and an additional survival “premium” for married men. We find little evidence of mortality differences between never-married, divorced/separated, and widowed statuses.
The collapse of single bubbles and approximation of the far-field acoustic emissions for cavitation induced by shock wave lithotripsy
Authors: JAMALUDDIN A. R. , BALL G. J. , TURANGAN C. K. , LEIGHTON T. G.
Published: April 2011

Recent clinical trials have shown the efficacy of a passive acoustic device used during shock wave lithotripsy (SWL) treatment. The device uses the far-field acoustic emissions resulting from the interaction of the therapeutic shock waves with the tissue and kidney stone to diagnose the effectiveness of each shock in contributing to stone fragmentation. This paper details simulations that supported the development of that device by extending computational fluid dynamics (CFD) simulations of the flow and near-field pressures associated with shock-induced bubble collapse to allow estimation of those far-field acoustic emissions. This is a required stage in the development of the device, because current computational resources are not sufficient to simulate the far-field emissions to ranges of O(10 cm) using CFD. Similarly, they are insufficient to cover the duration of the entire cavitation event, and here simulate only the first part of the interaction of the bubble with the lithotripter shock wave in order to demonstrate the methods by which the far-field acoustic emissions resulting from the interaction can be estimated. A free-Lagrange method (FLM) is used to simulate the collapse of initially stable air bubbles in water as a result of their interaction with a planar lithotripter shock. To estimate the far-field acoustic emissions from the interaction, this paper developed two numerical codes using the Kirchhoff and Ffowcs William–Hawkings (FW-H) formulations. When coupled to the FLM code, they can be used to estimate the far-field acoustic emissions of cavitation events. The limitation of the technique is that it assumes that no significant nonlinear acoustic propagation occurs outside the control surface. Methods are outlined for ameliorating this problem if, as here, computational resources cannot compute the flow field to sufficient distance, although for the clinical situation discussed, this limitation is tempered by the effect of tissue absorption, which here is incorporated through the standard derating procedure. This approach allowed identification of the sources of, and explanation of trends seen in, the characteristics of the far-field emissions observed in clinic, to an extent that was sufficient for the development of this clinical device.
On Partisan Political Justification
Authors: WHITE JONATHAN , YPI LEA
Published: April 2011

Political justification figures prominently in contemporary political theory, notably in models of deliberative democracy. This article articulates and defends the essential role of partisanship in this process. Four dimensions of justification are examined in detail: the constituency to which political justifications are offered, the circumstances in which they are developed, the ways in which they are made inclusive, and the ways in which they are made persuasive. In each case, the role of partisanship is probed and affirmed. Partisanship, we conclude, is indispensable to the kind of political justification needed to make the exercise of collective authority responsive to normative concerns.
Iron bound to pectin is utilised by rats
Authors: Miyada Tomihiro , Nakajima Akira , Ebihara Kiyoshi
Published: April 2011

In the present in vitro study, the effects of pH and ionic strength on the release of iron from pectin and the ability of pectin to reduce ferric iron to ferrous iron were examined. The bioavailability of Fe bound to pectin was evaluated in rats. The amount of Fe released from pectin was at a maximum at pH 2·0 and decreased as the pH value increased. At pH 2·0, the amount of Fe released from pectin increased as the ion length increased; at pH 5·0, ion length had no effect on pectin release. Pectin effectively reduced Fe from the ferric form to the ferrous form. In rats fed a pectin diet, where Fe bound to pectin was the only Fe source, the final Hb concentration using diets containing 4·4–5·7, 7·2 or 11·5 mg Fe/kg diet was equal to the concentration in rats fed diets containing 4·5, 7·6 or 13·5 mg ferrous iron/kg diet, respectively. Hb regeneration efficiencies in rats fed pectin diets were significantly different from rats fed a diet containing 13·5 mg ferrous iron/kg diet. In rats fed a diet with or without pectin, where ferric iron was the only Fe source, pectin increased the final Hb concentration. These results suggest that Fe bound to pectin is utilised by rats.
Effects of a high-protein, low-carbohydrate v. high-protein, moderate-carbohydrate weight-loss diet on antioxidant status, endothelial markers and plasma indices of the cardiometabolic profile
Authors: Johnstone Alexandra M. , Lobley Gerald E. , Horgan Graham W. , Bremner David M. , Fyfe Claire L. , Morrice Philip C. , Duthie Garry G.
Published: April 2011

There are concerns that weight-loss (WL) diets based on very low carbohydrate (LC) intake have a negative impact on antioxidant status and biomarkers of cardiovascular and metabolic health. Obese men (n 16) participated in a randomised, cross-over design diet trial, with food provided daily, at approximately 8·3 MJ/d (approximately 70 % of energy maintenance requirements). They were provided with two high-protein diets (30 % of energy), each for a 4-week period, involving a LC (4 % carbohydrate) and a moderate carbohydrate (MC, 35 % carbohydrate) content. Body weight was measured daily, and weekly blood samples were collected. On average, subjects lost 6·75 and 4·32 kg of weight on the LC and MC diets, respectively (P < 0·001, sed 0·350). Although the LC and MC diets were associated with a small reduction in plasma concentrations of retinol, vitamin E (α-tocopherol) and β-cryptoxanthin (P < 0·005), these were still above the values indicative of deficiency. Interestingly, plasma vitamin C concentrations increased on consumption of the LC diet (P < 0·05). Plasma markers of insulin resistance (P < 0·001), lipaemia and inflammation (P < 0·05, TNF-α and IL-10) improved similarly on both diets. There was no change in other cardiovascular markers with WL. The present data suggest that a LC WL diet does not impair plasma indices of cardiometabolic health, at least within 4 weeks, in otherwise healthy obese subjects. In general, improvements in metabolic health associated with WL were similar between the LC and MC diets. Antioxidant supplements may be warranted if LC WL diets are consumed for a prolonged period.
Umbilical venous–arterial plasma composition differences suggest differential incorporation of fatty acids in NEFA and cholesteryl ester pools
Authors: Lewis Rohan M. , Hanson Mark A. , Burdge Graham C.
Published: April 2011

The developing fetus requires an adequate supply of fatty acids, in particular PUFA, for optimal growth and development. Little is known about the transfer of fatty acids by the placenta into the fetal circulation. However, the molecular form in which fatty acids are transferred into the fetal circulation may influence their metabolism and hence their availability to specific tissues. The aim of the present study was to determine which lipid pools in the fetal circulation become enriched in fatty acids from the placenta by comparing the fatty acid compositions of individual lipid pools between umbilical venous (UV) and umbilical arterial (UA) plasma. Plasma from the UV and UA was collected after delivery from ten uncomplicated pregnancies, and the fatty acid composition of each lipid class was determined by GC. Total NEFA concentration in the UV was twofold higher than in the UA (P < 0·05) due to enrichment in 16 : 0, 16 : 1n-7, 18 : 1n-9, 18 : 1n-7, 18 : 2n-6, 20 : 3n-6, 20 : 4n-6, 24 : 0 and 22 : 6n-3. Total cholesteryl ester concentration was twofold higher in the UV than in the UA (P < 0·05) due to enrichment in 16 : 0, 16 : 1n-7, 18 : 0, 18 : 1n-9, 18 : 1n-7, 18 : 2n-6 and 20 : 4n-6. There were no significant UV–UA differences in the total concentration or composition of TAG or phosphatidylcholine. The present study demonstrates differential enrichment across the placenta of fatty acids into specific lipid pools in the fetal circulation. Such partitioning may facilitate supply of individual fatty acids to specific fetal tissues.
Modulatory effect of α-linolenic acid-rich garden cress (Lepidium sativumL.) seed oil on inflammatory mediators in adult albino rats
Authors: Diwakar Bastihalli Tukaramrao , Ramaswamy Lokesh Belur , Naidu Kamatham Akhilender
Published: April 2011

Vegetable oils containing α-linolenic acid (ALA; 18 : 3n-3) have been shown to modulate the functions of immunocompetent cells. The aim of the present study was to understand the modulatory effect of ALA-rich garden cress (Lepidium sativumL.) seed oil (GCO) on lipid composition, spleen lymphocyte (SL) proliferation and inflammatory mediator production by peritoneal macrophages (PMΦ) in rats. Female Wistar rats were fed diets containing either GCO (2·5, 5·0 and 10 %, w/w) or sunflower oil (SFO, 10 % w/w) for 8 weeks.Ex vivoproliferation of SL was measured by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. IL-2 and TNF-α in SL and PMΦ were analysed by ELISA. Inflammatory mediators such as NO, leukotriene B4(LTB4) and H2O2were measured in mitogen-activated PMΦ. GCO significantly increased the levels of ALA, EPA and DHA, but reduced linoleic acid and arachidonic acid in SL and PMΦ lipids. GCO (10 %) significantly decreased the concanavalin A (Con-A)- and phytohaemagglutinin-mediated proliferation of SL by 54 and 38 %, respectively, in comparison with SFO. A marginal decrease in IL-2 and TNF-α was observed in Con-A-stimulated SL and lipopolysaccharide-stimulated PMΦ. LTB4levels in Ca ionophore-stimulated PMΦ were reduced by 40 % in GCO-fed rats. NO release in response to various stimuli was significantly decreased in PMΦ of GCO-fed rats. The present study is the first report on the modulatory efficacy of GCO on immunomediators in rats. GCO modulated inflammatory mediators such as NO and LTB4, and thus may play a role in alleviating inflammatory conditions favourably.
Protein deficiency, but not zinc deficiency, reduces recovery of type 1 and type 2 muscle fibre diameters in the gastrocnemius muscle of growing rats
Authors: Prescod Alexia L. V. , Halliday William C. , Taylor Carla G.
Published: April 2011

The present study examines the effects of protein- and energy-type malnutrition in combination with Zn deficiency on the growth, serum insulin-like growth factor-1 (IGF-1), gastrocnemius muscle mass and fibre diameter of growing rats during a deficiency phase followed by nutritional rehabilitation. Rats (3-weeks old) were randomly assigned to baseline, or Zn-deficient (Z, < 1 mg Zn/kg), protein-deficient (P, 20 g protein/kg), combined Zn- and protein-deficient (ZP), energy-deficient (E, feed intake pair-fed to Z) or control (C, 30 mg Zn/kg and 170 g protein/kg) groups for a 3-week deficiency phase, followed by a 3-week repletion phase with the control diet. ATPase histochemical staining at pH 9·4 was used to differentiate type 1 and type 2 muscle fibres. After the deficiency phase, the ZP and P groups had lower body weight and smaller gastrocnemius muscle mass than the Z and E groups. Type 1 and 2 muscle fibre diameters (T1- and T2-MFD, respectively) were reduced in the ZP, P and Z groups compared with the E and C groups. Serum Zn was reduced in the ZP, P and Z groups, but serum IGF-1 was lowest in the Z and E groups. After the repletion phase, T1-MFD did not recover in the P and E groups nor T2-MFD in the P group, despite the P and E groups having a better recovery of body weight. In summary, previous protein deficiency, but not Zn deficiency, limited the recovery of both T1- and T2-MFD during nutritional repletion. The quality of skeletal muscle recovery in the malnourished groups was not associated with body weight, muscle mass, serum Zn or IGF-1 concentrations.
Consumption of a DHA-containing functional food during pregnancy is associated with lower infant ponderal index and cord plasma insulin concentration
Authors: Courville Amber B. , Harel Ofer , Lammi-Keefe Carol J.
Published: April 2011

DHA (22 : 6n-3) in pregnancy has previously been shown to benefit infant brain and retinal development. Fatty acid consumption during pregnancy may also have an impact on infant adipose tissue development. The objective of the present study was to assess the prenatal impact of a DHA-containing functional food (DHA-FF) on infant intra-uterine growth. This was a longitudinal, randomised, double-blinded, placebo-controlled trial. Pregnant women were assigned to consume a DHA-FF or placebo bar from 24 weeks' gestation until delivery. Blood samples were collected from mothers at baseline and delivery and from the umbilical cord at delivery. Plasma and erythrocyte fatty acids were analysed by GLC and plasma insulin concentrations were analysed using a commercially available ELISA kit. Infant birth weight and length were obtained at delivery and ponderal index (weight (g)/length (cm)3 × 100) was calculated. A total of forty-seven mothers completed the study. Infants of mothers consuming the DHA-FF during the last half of pregnancy had lower ponderal indices (β = 0·198,P < 0·05) and umbilical cord blood insulin concentrations (β = 0·743,P < 0·05) than infants of mothers consuming the placebo. Thus, DHA consumption during pregnancy may be advantageous with respect to infant body composition at birth and insulin sensitivity.
Autophagy up-regulation by early weaning in the liver, spleen and skeletal muscle of piglets
Authors: Zhang Shaojin , Li Xiao , Li Lei , Yan Xianghua
Published: April 2011

Autophagy, a catabolic process responsible for the degradation of cytosolic components and the preservation of cellular homeostasis in virtually all eukaryotic organisms, is up-regulated when nutrient supplies are limited. However, whether early weaning induces autophagy in infants is not completely clear. In the present study, we used piglets as the early-weaning model to examine the autophagic activity in different tissues in response to nutrient status. Western blot analysis demonstrated that microtubule-associated protein 1 light chain 3-II, a promising marker protein for macroautophagy, was expressed at a notably higher level at 12 and 24 h weaning treatments than without weaning treatment (P < 0·01), and that the p62 (sequestome 1; SQSTM1) expression level was significantly attenuated after weaning treatments (P < 0·01) in the liver, spleen and skeletal muscle tissues. In addition, autophagic vacuoles detected by transmission electron microscopy were dramatically accumulated in these tissues (P < 0·01). Together, these results indicate that autophagy induced by early weaning may be helpful for the physiological system, which controls the balance of energy and nutrients for basic cell functions in the piglet model.
Completions of Boolean algebras of projections and weak-star closures of C*-algebras on dual Banach spaces
Authors: Spain Philip G.
Published: April 2011

Palmer has shown that those hermitians in the weak-star operator closure of a commutative C*-algebra represented on a dual Banach space X that are known to commute with the initial C*-algebra form the real part of a weakly closed C*-algebra on X. Relying on a result of Murphy, it is shown in this paper that this last proviso may be dropped, and that the weak-star closure is even a W*-algebra.

When the dual Banach space X is separable, one can prove a similar result for C*-equivalent algebras, via a ‘separable patch’ completion theorem for Boolean algebras of projections on such spaces.
Nostalgia, Class and Rurality in Empire Falls
Authors: DENTON STACY
Published: April 2011

In American society, rural spaces – particularly those of the working class – are seen as stagnant holdovers from a temporal past that “modern” society has evolved beyond. As a result, working-class rurality and those living within these places are viewed as static, ignorant, insular and so on: whatever places do not conform to the appearance of “modern” progress and development simply must be regressed, on both socioeconomic and cultural levels. While scholars in some disciplines are attempting to redress this misconception, other disciplines (like literary studies) largely align with the mainstream perspective that rurality represents a regressed past to our evolved present. However, despite the critical lack of attention to rurality as a viable space in the present, we can see in various fictional works that working-class rural spaces can effectively show us the interrelationship of rural spaces with “modern” society and culture in the present, the continuing relevance and deep history alike of said spaces, and the potential of these fictional working-class rural places to confront America's norms of progress and development within and without their fictional borders. Richard Russo's fiction illustrates the potential to bring out this critical working-class rural voice. Russo's fictional treatments afford the reader an opportunity to witness the ever-changing complexity (not the temporal and cultural regression) of working-class rurality. In turn, Russo's fictional working-class rural spaces offer a counterperspective to the mainstream (defined here as middle-class and (sub)urban) notions of progress that otherwise dismiss these perspectives. In his book Empire Falls, Russo uses nostalgia to assert this counterperspective. This nostalgia not only reaffirms the postwar and early twenty-first-century working-class rural identity of Empire Falls, but it also offers a critique of dominant conceptions of progress and development that continue into our present.
The use of transient evoked otoacoustic emissions as a hearing screen following grommet insertion
Authors: Dale O T , McCann L J , Thio D , Wells S C , Drysdale A J
Published: April 2011

Objective:

This study aimed to evaluate the sensitivity of transient evoked otoacoustic emission testing as a screening tool for hearing loss in children, after grommet insertion.

Method:

A prospective study was conducted of 48 children (91 ears) aged three to 16 years who had undergone grommet insertion for glue ear. At post-operative review, pure tone audiometry was performed followed by transient evoked otoacoustic emission testing. Outcomes for both tests, in each ear, were compared.

Results:

The pure tone audiometry threshold was ≤20 dB in 85 ears (93.4 per cent), 25 dB in two ears (2.2 per cent) and ≥30 dB in four ears (4.4 per cent). Transient evoked otoacoustic emissions were detected in 69 ears (75.8 per cent). The sensitivity of transient evoked otoacoustic emission testing for detecting hearing loss was 100 per cent for ≥30 dB loss but only 66.7 per cent for ≥25 dB loss.

Conclusion:

Transient evoked otoacoustic emission testing offers a sensitive means of detecting hearing loss of ≥30 dB following grommet insertion in children. However, the use of such testing as a screening tool may miss some cases of mild hearing loss.
The point-touch technique for botulinum toxin injection in adductor spasmodic dysphonia: quality of life assessment
Authors: Morzaria S , Damrose E J
Published: April 2011

Background:

Botulinum toxin injection under electromyographic guidance is the ‘gold standard’ for adductor spasmodic dysphonia treatment. The point-touch technique, an alternative injection method which relies on anatomical landmarks, is cheaper, quicker and more accessible, but has not yet gained widespread acceptance due to concerns about patient satisfaction.

Objective:

To assess swallowing and voice-related quality of life following point-touch botulinum toxin injection in adductor spasmodic dysphonia patients.

Setting:

Stanford University Voice and Swallowing Center.

Design:

Prospective case series (evidence level four).

Methods:

Consecutive adductor spasmodic dysphonia patients with a stable botulinum toxin dose–response relationship were recruited prospectively. The Eating Assessment Tool and Voice-Related Quality of Life questionnaires were completed pre-treatment and at 10 and 30 per cent completion of the injection cycle, respectively.

Results:

Thirty-seven patients completed follow up. The mean total botulinum toxin dose was 0.88 units. Pre-treatment Voice-Related Quality of Life questionnaire results reflected the burden of disease. Post-treatment Eating Assessment Tool and Voice-Related Quality of Life questionnaire results were collected at 2.53 and 7.84 weeks, respectively; the former showed an increase in dysphagia, albeit statistically insignificant, while the latter showed significantly improved scores (both domain and total).

Conclusion:

The point-touch technique is a viable alternative for botulinum toxin injection in the treatment of adductor spasmodic dysphonia.
The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus)
Authors: McINNES L. M. , GILLETT A. , HANGER J. , REID S. A. , RYAN U. M.
Published: April 2011

Whole blood collected from koalas admitted to the Australian Zoo Wildlife Hospital (AZWH), Beerwah, QLd, Australia, during late 2006–2009 was tested using trypanosome species-specific 18S rDNA PCRs designed to amplify DNA fromTrypanosoma irwini, T. gillettiandT. copemani. Clinical records for each koala sampled were reviewed and age, sex, blood packed cell volume (PCV), body condition, signs of illness, blood loss, trauma, chlamydiosis, bone marrow disease, koala AIDS and hospital admission outcome (‘survival’ / ‘non-survival’) were correlated with PCR results. Overall 73·8% (439/595) of the koalas were infected with at least 1 species of trypanosome.Trypanosoma irwiniwas detected in 423/595 (71·1%),T. gillettiin 128/595 (21·5%) andT. copemaniin 26/595 (4·4%) of koalas. Mixed infections were detected in 125/595 (21%) with co-infections ofT. irwiniandT. gilletti(101/595, 17%) being most common. There was a statistical association between infection withT. gillettiwith lower PCV values and body condition scores in koalas with signs of chlamydiosis, bone marrow disease or koala AIDS. No association betweenT. gillettiinfection and any indicator of health was observed in koalas without signs of concurrent disease. This raises the possibility thatT. gillettimay be potentiating other disease syndromes affecting koalas.
Environmental constraints influencing survival of an African parasite in a north temperate habitat: effects of temperature on egg development
Authors: TINSLEY R. C. , YORK J. E. , EVERARD A. L. E. , STOTT L. C. , CHAPPLE S. J. , TINSLEY M. C.
Published: April 2011

Factors affecting survival of parasites introduced to new geographical regions include changes in environmental temperature. Protopolystoma xenopodis is a monogenean introduced with the amphibian Xenopus laevis from South Africa to Wales (probably in the 1960s) where low water temperatures impose major constraints on life-cycle processes. Effects were quantified by maintenance of eggs from infections in Wales under controlled conditions at 10, 12, 15, 18, 20 and 25°C. The threshold for egg viability/ development was 15°C. Mean times to hatching were 22 days at 25°C, 32 days at 20°C, extending to 66 days at 15°C. Field temperature records provided calibration of transmission schedules. Although egg production continues year-round, all eggs produced during >8 months/ year die without hatching. Output contributing significantly to transmission is restricted to 10 weeks (May–mid-July). Host infection, beginning after a time lag of 8 weeks for egg development, is also restricted to 10 weeks (July–September). Habitat temperatures (mean 15·5°C in summer 2008) allow only a narrow margin for life-cycle progress: even small temperature increases, predicted with ‘global warming’, enhance infection. This system provides empirical data on the metrics of transmission permitting long-term persistence of isolated parasite populations in limiting environments.
MixedTheileriainfections in free-ranging buffalo herds: implications for diagnosingTheileria parvainfections in Cape buffalo (Syncerus caffer)
Authors: PIENAAR RONEL , POTGIETER FRED T. , LATIF ABDALLA A. , THEKISOE ORIEL M. M. , MANS BEN J.
Published: April 2011

Buffalo-adaptedTheileria parvacauses Corridor disease in cattle. Strict control measures therefore apply to the movement of buffalo in South Africa and include mandatory testing of buffalo for the presence ofT. parva. The official test is a real-time hybridization PCR assay that amplifies the V4 hypervariable region of the 18S rRNA gene ofT. parva, T.sp. (buffalo) andT.sp. (bougasvlei). The effect that mixedT. parvaandT.sp. (buffalo)-like infections have on accurateT. parvadiagnosis was investigated in this study.In vitromixed infection simulations indicated PCR signal suppression at 100 to 1000-foldT.sp. (buffalo) excess at lowT. parvaparasitaemia. Suppression of PCR signal was found in field buffalo with mixed infections. TheT. parva-positive status of these cases was confirmed by selective suppression ofT.sp. (buffalo) amplification using a locked nucleic acid clamp and independent assays based on the p67, p104 andTprgenes. The incidence of mixed infections in the Corridor disease endemic region of South Africa is significant, while the prevalence in buffalo outside the endemic area is currently low. A predicted increase ofT.sp. (buffalo)-like infections can affect future diagnoses where mixed infections occur, prompting the need for improvements in current diagnostics.
Accius, Porcius Licinus, and the Beginning of Latin Literature
Authors: Welsh Jarrett T.
Published: April 2011

This paper re-examines the scholarly views about the beginning of Latin poetry that were current in the late second centuryb.c., and proposes that the earliest scholars, specifically Accius and Porcius Licinus, marked Livius Andronicus’ hymn to Juno Regina of 207b.c., rather than a play in 197b.c., as the fountainhead of Latin literature. Those histories would suggest that the dominant interpretation put poetry at the heart of the affairs of the state at war; when in the early 40sb.c. Varro and his contemporaries disproved Accius, they were both bringing out new facts about Livius’ earlier career, and rewriting the history of Latin poetry, so that it had its origins in peace, rather than in war.
On weak KAM theory for N-body problems
Authors: MADERNA EZEQUIEL
Published: April 2011

We consider N-body problems with potential 1/r2κ, where κ∈(0,1), including the Newtonian case (κ=1/2). Given R>0 and T>0, we find a uniform upper bound for the minimal action of paths binding, in time T, any two configurations which are contained in some ball of radius R. Using cluster partitions, we obtain from these estimates the Hölder regularity of the critical action potential (i.e. of the minimal action of paths binding two configurations in free time). As an application, we establish the weak KAM theorem for these N-body problems, i.e. we prove the existence of fixed points of the Lax–Oleinik semigroup, and we show that they are global viscosity solutions of the corresponding Hamilton–Jacobi equation. We also prove that there are invariant solutions for the action of isometries on the configuration space.
Escape rates for Gibbs measures
Authors: FERGUSON ANDREW , POLLICOTT MARK
Published: April 2011

In this paper we study the asymptotic behaviour of the escape rate of a Gibbs measure supported on a conformal repeller through a small hole. There are additional applications to the convergence of the Hausdorff dimension of the survivor set.
The social lives of rural Australian nursing home residents
Authors: PARMENTER GLENDA , CRUICKSHANK MARY , HUSSAIN RAFAT
Published: April 2011

Contact with family and friends, in the form of visiting, is very important to the quality of the lives of rural nursing home residents. However, there has been little recent research that examines the frequency and determinants of visits to rural nursing homes and none in the rural Australian context. This study aimed to address this gap in the literature. A telephone survey with a close family member (N=257) of each participating resident in the rural New England area of New South Wales, Australia gathered data about 3,738 people who formed the potential social networks of these residents. This study found that the wider, potential, social networks of rural nursing home residents comprised approximately 17 people and involved a wide range of family and friends. However, their actual social networks consisted of approximately two females, daughters and friends, who had high-quality relationships with the resident and who visited at least once per month. In contrast to previous assertions that nursing home residents have robust support from their family and friends, the actual social networks of these residents have dwindled considerably over recent years, which may place them at risk of social isolation. This study has implications for nursing home policy and practice and recommendations for addressing the risk of social isolation that rural nursing home residents face are made.
Spectral theory of large Wiener–Hopf operators with complex-symmetric kernels and rational symbols
Authors: BÖTTCHER ALBRECHT , GRUDSKY SERGEI , ISERLES ARIEH
Published: April 2011

This paper is devoted to the asymptotic behaviour of individual eigenvalues of truncated Wiener–Hopf integral operators over increasing intervals. The kernel of the operators is complex-symmetric and has a rational Fourier transform. Under additional hypotheses, the main result describes the location of the eigenvalues and provides their asymptotic expansions in terms of the reciprocal of the length of the truncation interval. Also determined is the structure of the eigenfunctions.
On the information content of ratings: an analysis of the origin of Moody's stock and bond ratings
Authors: Wilson Berry K.
Published: April 2011

John Moody published his first railroad security analysis and ratings manual in April 1909. This study analyzes several current issues by looking back at Moody's original intentions for constructing a ratings system. The study analyzes whether Moody intended his ratings to reflect his private information, or rather, to serve some alternative role, as with monitoring conflicts of interests or realizing informational economies of scale. The study uses an ordinal regression approach to evaluate a set of explanatory variables, constructed from both the manual itself and the panic months of 1907, to test the potential information content of Moody's ratings. At the time of Moody's first rating system, the illiquidity of the US Treasury market forced investors to seek alternative ‘high-quality’ securities. Indeed, Moody rated 38.94 percent of railroad bonds as Aaa, and rated 85.25 percent of railroad bonds as A, Aa or Aaa in his universe of railroad bonds rated. To further test the informational content of Moody's ratings, the study pursues a structural default analysis during the panic year of 1907, which yields results that indicate that the default risk of railroad securities was quite low at the time. These results provide justification for the high overall ratings that Moody assigned to railroad securities, and thus their role as near risk-free securities. Therefore, railroad securities, and Moody's ratings, played a particularly important role in the financial system at the time.
Analysis of Elemental Composition of the Eggshell before and after Incubation in the Loggerhead Turtle (Caretta caretta) in Oman
Authors: Al-Bahry S.N. , Mahmoud I.Y. , Melghit K. , Al-Amri I.
Published: April 2011

To date, there are limited studies on loggerhead turtle (Caretta caretta) eggshell ultrastructure and its elemental composition. Eggs were collected from turtle nests immediately after oviposition and post hatching. Three eggshell layers were recognized. The outer calcareous layer consists of loose nodular units of different shapes and sizes with loose attachment between the units, resulting in numerous spaces and openings. Each unit consists of CaCO3crystals in aragonite (99%) and calcite (1%). The middle layer has several strata with numerous openings connecting the calcareous and the inner shell membrane. Crystallites of the middle layer are a mix of amorphous material with aragonite (62%) and calcite (38%). The inner shell membrane has numerous reticular fibers mixed predominantly with halite (NaCl) and small amounts of sylvite. Thermogravimetry analysis of the calcareous showed a low exothermic peak at 425°C, which corresponds to a transitional phase from aragonite to calcite. A high endothermic peak at 814°C corresponds to decomposition of calcite CaCO3to CaO and CO2. Electron diffraction confirmed the presence of NaCl halite crystal. A significant difference was found in the percentage of elements and crystal configurations in the three layers. This study has value in assessing the emergence success in this endangered species.
An unexpected outcome of radiotherapy planning in implant-based breast reconstruction: a case series
Authors: Sepehripour S , Ridha H , Malata CM
Published: April 2011

We describe two cases of cellulitis occurring around ink sites, following tattooing for adjuvant radiotherapy in two patients who had undergone latissimus dorsi-with-implant breast reconstructions. One patient was successfully treated with intravenous antibiotics. The second patient developed a peri-implant infection requiring implant removal. Patients with implant-based breast reconstructions should be warned of the potential infection risk of radiotherapy tattooing.
Historical Perspective on Computational Star Formation
Authors: Larson Richard B.
Published: April 2011

The idea that stars are formed by gravity goes back more than 300 years to Newton, and the idea that gravitational instability plays a role goes back more than 100 years to Jeans, but the idea that stars are forming at the present time in the interstellar medium is more recent and did not emerge until the energy source of stars had been identified and it was realized that the most luminous stars have short lifetimes and therefore must have formed recently. The first suggestion that stars may be forming now in the interstellar medium was credited by contemporary authors to a paper by Spitzer in 1941 in which he talks about the formation of interstellar condensations by radiation pressure, but then oddly says nothing about star formation. That may be because, as Spitzer later told me, when he first suggested very tentatively in a paper submitted to The Astrophysical Journal that stars might be forming now from interstellar matter, this was considered a radical idea and the referee said it was much too speculative and should be taken out of the paper. So Spitzer removed the speculation about star formation from the published version of his paper.
Historical perspective on astrophysical MHD simulations
Authors: Norman Michael L.
Published: April 2011

This contribution contains the introductory remarks that I presented at IAU Symposium 270 on “Computational Star Formation” held in Barcelona, Spain, May 31–June 4, 2010. I discuss the historical development of numerical MHD methods in astrophysics from a personal perspective. The recent advent of robust, higher-order accurate MHD algorithms and adaptive mesh refinement numerical simulations promises to greatly improve our understanding of the role of magnetic fields in star formation.
Pre-main sequence multiple systems
Authors: Bouy Hervé
Published: April 2011

It is now well established that the majority of young stars are found in multiple systems, so that any theory of stellar formation must account for their existence and properties. Studying the properties of multiple star systems therefore represents a very powerful approach to place observational constraints on star formation theories. Additionally, multiple systems offer other advantages. They provide the most accurate and unambiguous way to measure masses, using orbital fitting and Kepler's laws, and even the stellar radius in the special case of eclipsing binaries. They also allow to compare the properties of 2 coeval objects with different masses, providing important tests for the evolutionary models.
Morphological Complexity of Protostellar Envelopes
Authors: Tobin John J. , Hartmann Lee , Bergin Edwin , Looney Leslie W. , Chiang Hsin-Fang , Heitsch Fabian
Published: April 2011

Extinction maps at 8μm from the Spitzer Space Telescope show that many Class 0 protostars exhibit complex, irregular, and non-axisymmetric structure within the densest regions of their dusty envelopes. Many of the systems have highly irregular and non-axisymmetric morphologies on scales ~1000 AU, with a quarter of the sample exhibiting filamentary or flattened dense structures. Complex envelope structure is observed in regions spatially distinct from outflow cavities, and the densest structures often show no systematic alignment perpendicular to the cavities. We suggest that the observed envelope complexity is the result of collapse from protostellar cores with initially non-equilibrium structures. The striking non-axisymmetry in many envelopes could provide favorable conditions for the formation of binary systems. We then show that the kinematics around L1165 as probed with N2H+ are indicative of asymmetric infall; the velocity gradient is not perpendicular to the outflow.
Recent Developments in Simulations of Low-mass Star Formation
Authors: Machida Masahiro N.
Published: April 2011

In star forming regions, we can observe different evolutionary stages of various objects and phenomena such as molecular clouds, protostellar jets and outflows, circumstellar disks, and protostars. However, it is difficult to directly observe the star formation process itself, because it is veiled by the dense infalling envelope. Numerical simulations can unveil the star formation process in the collapsing gas cloud. Recently, some studies showed protostar formation from the prestellar core stage, in which both molecular clouds and protostars are resolved with sufficient spatial resolution. These simulations showed fragmentation and binary formation, outflow and jet driving, and circumstellar disk formation in the collapsing gas clouds. In addition, the angular momentum transfer and dissipation process of the magnetic field in the star formation process were investigated. In this paper, I review recent developments in numerical simulations of low-mass star formation.
Observations of the IMF in clusters
Authors: Ascenso Joana
Published: April 2011

Stars form from molecular clouds, mostly in clusters with tens to tens of thousands of members, and the mass distribution within these clusters, or the Initial Mass Function, seems to be invariable against many parameters and over a wide range of masses. However, masses are a very difficult quantity to assess, and the precision of our determinations of the IMF is systematically lower than usually quoted. I will discuss the process of determining masses from observations and the type of uncertainties associated with this process.
Insights on molecular cloud structure
Authors: Alves João , Lombardi Marco , Lada Charles
Published: April 2011

Stars form in the densest regions of clouds of cold molecular hydrogen. Measuring structure in these clouds is far from trivial as 99% of the mass of a molecular cloud is inaccessible to direct observation. Over the last decade we have been developing an alternative, more robust density tracer technique based on dust extinction measurements towards background starlight. The new technique does not suffer from the complications plaguing the more conventional molecular line and dust emission techniques, and when used with these can provide unique views on cloud chemistry and dust grain properties in molecular clouds. In this brief communication we summarize the main results achieved so far using this technique.
Theory of Cluster Formation: Effects of Magnetic Fields
Authors: Nakamura Fumitaka , Li Zhi-Yun
Published: April 2011

Stars form predominantly in clusters inside dense clumps of molecular clouds that are both turbulent and magnetized. The typical size and mass of the cluster-forming clumps are ~1 pc and ~102 – 103 M⊙, respectively. Here, we discuss some recent progress on numerical simulations of clustered star formation in such parsec-scale dense clumps with emphasis on the role of magnetic fields. The simulations have shown that magnetic fields tend to slow down global gravitational collapse and thus star formation, especially in the presence of protostellar outflow feedback. Even a relatively weak magnetic field can retard star formation significantly, because the field is amplified by supersonic turbulence to an equipartition strength. However, in such a case, the distorted field component dominates the uniform one. In contrast, if the field is moderately-strong, the uniform component remains dominant. Such a difference in the magnetic structure is observed in simulated polarization maps of dust thermal emission. Recent polarization measurements show that the field lines in nearby cluster-forming clumps are spatially well-ordered, indicative of a rather strong field. In such strongly-magnetized clumps, star formation should proceed relatively slowly; it continues for at least several global free-fall times of the parent dense clump (tff ~ a few × 105 yr).