bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S2 from Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals
Authors: Hofmann Jonathan N. , Birmann Brenda M. , Teras Lauren R. , Pfeiffer Ruth M. , Wang Ye , Albanes Demetrius , Baris Dalsu , Colditz Graham A. , De Roos Anneclaire J. , Giles Graham G. , Hosgood H. Dean , Lan Qing , Landgren Ola , Liao Linda M. , Rothman Nathaniel , Weinstein Stephanie J. , Pollak Michael N. , Neuhouser Marian L. , Purdue Mark P.
Published: April 2023

Circulating levels of high-molecular-weight adiponectin and risk of multiple myeloma.
Table S2 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: April 2023

CpGs and genes associated with differential methylation and expression with respect to high-risk (HR) neuroblastoma disease
Supplementary Figure S1 from Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals
Authors: Hofmann Jonathan N. , Birmann Brenda M. , Teras Lauren R. , Pfeiffer Ruth M. , Wang Ye , Albanes Demetrius , Baris Dalsu , Colditz Graham A. , De Roos Anneclaire J. , Giles Graham G. , Hosgood H. Dean , Lan Qing , Landgren Ola , Liao Linda M. , Rothman Nathaniel , Weinstein Stephanie J. , Pollak Michael N. , Neuhouser Marian L. , Purdue Mark P.
Published: April 2023

Risk of MM in relation to circulating total adiponectin levels estimated using a restricted cubic spline regression model with 4 knots.
Supplemental Figures S1-S6 from EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer
Authors: Amato Katherine R. , Wang Shan , Tan Li , Hastings Andrew K. , Song Wenqiang , Lovly Christine M. , Meador Catherine B. , Ye Fei , Lu Pengcheng , Balko Justin M. , Colvin Daniel C. , Cates Justin M. , Pao William , Gray Nathanael S. , Chen Jin
Published: April 2023

Localization of EPHA2 in erlotinib resistant cells (S1); Validation of EPHA2 antibody specificity in patient tumor specimens (S2); EPHA2 kinase activity is required in maintaining cell viability of erlotinib resistant lung cancer (S3); Biochemical analysis of TKI-Â­â€�resistant tumors from EGFRL858R+T790MEphA2-Â­â€�/-Â­â€� and control mice (S4); Signaling analysis in EPHA2 knockdown cells by siRNA-Â­â€�mediated gene silencing (S5); Localization of EPHA2 upon ligand or EPHA2 inhibitor treatment (S6).
Supplemental Figure 5 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: April 2023

The effect of herbacetin on AP-1 upstream proteins. Colon cancer cells were treated with herbacetin for 48 h and expression of total and phosphorylated ERKs and RSK and total ODC was determined by Western blotting. Beta-Actin was used as a loading control. Similar results were obtained from 3 independent experiments and representative blots are shown.
Supplementary Figure S5 from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: April 2023

PAI-1 expression in intrapleural tumors consisting of EHMES-10 or MSTO-211H cells
Supplemental Figure 10 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: April 2023

The effect of herbacetin or DFMO on hearing in C57BL/6 mice as measured by PPI. Vehicle, herbacetin (100 mg/kg B.W. p.o. or 2 mg/kg B.W. i.p.) or DFMO (1 g/kg B.W. p.o.) was administered by gavage or intraperitoneal injection 5 times per week for 5 weeks. (A) DFMO significantly decreased hearing (measured as prepulse inhibition or PPI) on day 35. Hearing as measured by PPI was not affected by oral administration (B) or intraperitoneal injection (C) of herbacetin. Data are shown as mean values {plus minus} S.E. The asterisk (*) indicates a significant decrease (p < 0.05) in hearing in DFMO-treated mice compared to the vehicle-treated group.
Supplemental Figure 1 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: April 2023

Effect of herbacetin or kaempferol on ODC activity. (A) Herbacetin or (B) kaempferol was modeled as an allosteric inhibitor with the ODC crystal structure. (C) The effect of herbacetin or kaempferol (upper panels) on ODC activity (lower panel) was assessed using a human ODC recombinant protein. Each reaction was incubated at 37{degree sign}C for 1 h and ODC activity was measured as the release of CO2 from L-[1-C14] ornithine. Data are represented as mean values {plus minus} S.D. of triplicate experiments. The asterisk (*) indicates a significant decrease (p < 0.05) in ODC activity between herbacetin-treated samples compared to untreated or kaempferol-treated samples.
Supplementary Figure Legends from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: April 2023

Legends for Supplementary Figures S1-S8
Supplementary Figure Legends from An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer
Authors: Olow Aleksandra , Chen Zhongzhong , Niedner R. Hannes , Wolf Denise M. , Yau Christina , Pankov Aleksandr , Lee Evelyn Pei Rong , Brown-Swigart Lamorna , van ‘t Veer Laura J. , Coppé Jean-Philippe
Published: April 2023

Legends for Supplementary Figures S1-S17.
Supplementary Methods from Redirecting Transport of Nanoparticle Albumin-Bound Paclitaxel to Macrophages Enhances Therapeutic Efficacy against Liver Metastases
Authors: Tanei Tomonori , Leonard Fransisca , Liu Xuewu , Alexander Jenolyn F. , Saito Yuki , Ferrari Mauro , Godin Biana , Yokoi Kenji
Published: April 2023

Description of additional methods and procedures used in the study.
Supplementary Table 2 from Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Authors: Osman Abdullah A. , Neskey David M. , Katsonis Panagiotis , Patel Ameeta A. , Ward Alexandra M. , Hsu Teng-Kuei , Hicks Stephanie C. , McDonald Thomas O. , Ow Thomas J. , Alves Marcus Ortega , Pickering Curtis R. , Skinner Heath D. , Zhao Mei , Sturgis Eric M. , Kies Merrill S. , El-Naggar Adel , Perrone Federica , Licitra Lisa , Bossi Paolo , Kimmel Marek , Frederick Mitchell J. , Lichtarge Olivier , Myers Jeffrey N.
Published: April 2023

Supplementary Table 2: Univariate analysis of overall survival.
Supplementary Table 1 from Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Authors: Osman Abdullah A. , Neskey David M. , Katsonis Panagiotis , Patel Ameeta A. , Ward Alexandra M. , Hsu Teng-Kuei , Hicks Stephanie C. , McDonald Thomas O. , Ow Thomas J. , Alves Marcus Ortega , Pickering Curtis R. , Skinner Heath D. , Zhao Mei , Sturgis Eric M. , Kies Merrill S. , El-Naggar Adel , Perrone Federica , Licitra Lisa , Bossi Paolo , Kimmel Marek , Frederick Mitchell J. , Lichtarge Olivier , Myers Jeffrey N.
Published: April 2023

Supplementary Table 1: TP53 mutations scored and stratified by EAp53 and Poeta classification in the platinum based induction chemotherapy cohort.
Supplemental Table 3 from Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis
Authors: Quick Laura , Young Robert , Henrich Ian C. , Wang Xiaoke , Asmann Yan W. , Oliveira Andre M. , Chou Margaret M.
Published: April 2023

NF dataset p< 0.05
Supplemental Figure 2 from Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis
Authors: Quick Laura , Young Robert , Henrich Ian C. , Wang Xiaoke , Asmann Yan W. , Oliveira Andre M. , Chou Margaret M.
Published: April 2023

GSEA plots
Supplemental figure and table legends from Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages
Authors: Zhao Jun-Long , Huang Fei , He Fei , Gao Chun-Chen , Liang Shi-Qian , Ma Peng-Fei , Dong Guang-Ying , Han Hua , Qin Hong-Yan
Published: April 2023

Legend for Supplemental Figures S1-S14 and for Supplemental Tables S1-S2.
Figure S5 from miR-214 and miR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer
Authors: Orso Francesca , Quirico Lorena , Virga Federico , Penna Elisa , Dettori Daniela , Cimino Daniela , Coppo Roberto , Grassi Elena , Elia Angela Rita , Brusa Davide , Deaglio Silvia , Brizzi Maria Felice , Stadler Michael B. , Provero Paolo , Caselle Michele , Taverna Daniela
Published: April 2023

miR-148b expression modulations in normal or tumor breast cells
Supplementary Table 2 from Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma
Authors: De Rienzo Assunta , Archer Michael A. , Yeap Beow Y. , Dao Nhien , Sciaranghella Daniele , Sideris Antonios C. , Zheng Yifan , Holman Alexander G. , Wang Yaoyu E. , Dal Cin Paola S. , Fletcher Jonathan A. , Rubio Renee , Croft Larry , Quackenbush John , Sugarbaker Peter E. , Munir Kiara J. , Battilana Jesse R. , Gustafson Corinne E. , Chirieac Lucian R. , Ching Soo Meng , Wong James , Tay Liang Chung , Rudd Stephen , Hercus Robert , Sugarbaker David J. , Richards William G. , Bueno Raphael
Published: April 2023

List of the tumor specific mutations identified by whole-genome sequencing and validated in the 10 pairs of MPM tumor and germline DNA samples
Supplemental Table 2 from Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease
Authors: Murphy Stephen J. , Hart Steven N. , Halling Geoffrey C. , Johnson Sarah H. , Smadbeck James B. , Drucker Travis , Lima Joema Felipe , Rohakhtar Fariborz Rakhshan , Harris Faye R. , Kosari Farhad , Subramanian Subbaya , Petersen Gloria M. , Wiltshire Timothy D. , Kipp Benjamin R. , Truty Mark J. , McWilliams Robert R. , Couch Fergus J. , Vasmatzis George
Published: April 2023

Combined Mate Pair and Whole Exome Sequencing data for all 24 tumors described in this study.
Supplemental Figure Legeneds from Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease
Authors: Murphy Stephen J. , Hart Steven N. , Halling Geoffrey C. , Johnson Sarah H. , Smadbeck James B. , Drucker Travis , Lima Joema Felipe , Rohakhtar Fariborz Rakhshan , Harris Faye R. , Kosari Farhad , Subramanian Subbaya , Petersen Gloria M. , Wiltshire Timothy D. , Kipp Benjamin R. , Truty Mark J. , McWilliams Robert R. , Couch Fergus J. , Vasmatzis George
Published: April 2023

Supplemental figure legends to accompany supplemental data file
Supplementary Figure S6 from miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3
Authors: Zhou Ying , Dang Jason , Chang Kung-Yen , Yau Edwin , Aza-Blanc Pedro , Moscat Jorge , Rana Tariq M.
Published: April 2023

Testing of Individual LAMB3 and FAK siRNAs Rule Out Off-Target Effects.
Supplementary Material and Methods from EGF816 Exerts Anticancer Effects in Non–Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor
Authors: Jia Yong , Juarez Jose , Li Jie , Manuia Mari , Niederst Matthew J. , Tompkins Celin , Timple Noelito , Vaillancourt Mei-Ting , Pferdekamper AnneMarie Culazzo , Lockerman Elizabeth L. , Li Chun , Anderson Jennifer , Costa Carlotta , Liao Debbie , Murphy Eric , DiDonato Michael , Bursulaya Badry , Lelais Gerald , Barretina Jordi , McNeill Matthew , Epple Robert , Marsilje Thomas H. , Pathan Nuzhat , Engelman Jeffrey A. , Michellys Pierre-Yves , McNamara Peter , Harris Jennifer , Bender Steven , Kasibhatla Shailaja
Published: April 2023

This file contains additional Materials and Methods that are not listed in the main text.
Figure S3 from PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer
Authors: Nagarsheth Nisha , Peng Dongjun , Kryczek Ilona , Wu Ke , Li Wei , Zhao Ende , Zhao Lili , Wei Shuang , Frankel Timothy , Vatan Linda , Szeliga Wojciech , Dou Yali , Owens Scott , Marquez Victor , Tao Kaixiong , Huang Emina , Wang Guobin , Zou Weiping
Published: April 2023

Figure S3: Clinical relevance of CXCL9 and CXCL10 expression in colon cancer
Supplementary Material from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Portions of Materials and Methods and Supplementary Tables 1 and 2. Table S1: Primer sequences for ChIP experiment Table S2: Primer sequences for qRT-PCR
Supplementary Figure Legends from A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis
Authors: Fang Liang , Zhu Qionghua , Neuenschwander Martin , Specker Edgar , Wulf-Goldenberg Annika , Weis William I. , von Kries Jens P. , Birchmeier Walter
Published: April 2023

Supplementary figure legends
Supplementary Table S1 from Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance
Authors: Busch Susann , Sims Andrew H. , Stål Olle , Fernö Mårten , Landberg Göran
Published: April 2023

Multivariate analysis of recurrence-free survival regarding prognostic information of TGFBR2.
Supplemental Figures 1 through 5 from Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy
Authors: Pilon-Thomas Shari , Kodumudi Krithika N. , El-Kenawi Asmaa E. , Russell Shonagh , Weber Amy M. , Luddy Kimberly , Damaghi Mehdi , Wojtkowiak Jonathan W. , Mulé James J. , Ibrahim-Hashim Arig , Gillies Robert J.
Published: April 2023

Supplemental Figure S1: Inhibition of PI3 kinase signaling leads to loss of T cell function. Activated T cells were cultured at pH 6.6 or 7.4 for 24h in presence or absence of the PI3K Supplemental Figure S2: OT-1 T cell metabolism. OT-1 T cells were cultured with OVASIINFEKL peptide for 48 hours at either pH 6.6 or 7.4. Cells were subsequently metabolically profiled using a Seahorse XF-96 analyzer. Supplemental Figure S3: Knocking out the acid sensor, TDAG8, does not rescue IFN-gamma production by T cells. T cells were isolated from TDAG8 k/o or wild-type (WT) mice and stimulated in the presence of 10 ug/ml plate-bound anti-CD3 antibodies for 48 hours at pH 6.6 or 7.4. Supernatants were collected and IFN-gamma was measured by ELISA. Supplemental Figure S4: Representative B16 tumors in mice treated with anti-CTLA4 antibodies with or without buffer therapy. Supplemental Figure S5: Buffer therapy has little effect on systemic T cell activity in B16- bearing mice treated with anti-PD-1 antibody. inhibitor BEZ-235.
Supplementary Movie 2 from Modeling Spontaneous Metastasis following Surgery: An In Vivo-In Silico Approach
Authors: Benzekry Sebastien , Tracz Amanda , Mastri Michalis , Corbelli Ryan , Barbolosi Dominique , Ebos John M.L.
Published: April 2023

Supplementary Movie 2: Primary tumor (PT) was assumed to be detected when reaching the size of 4.32 cm in diameter. Post-diagnosis PT growth and development of metastases in the case of no surgical intervention are indicated as dashed line in the left plot and white bars in the histogram on the right, respectively.
Supplementary Movie 2 from Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells
Authors: Cheng Chun-Ting , Kuo Ching-Ying , Ouyang Ching , Li Chien-Feng , Chung Yiyin , Chan David C. , Kung Hsing-Jien , Ann David K.
Published: April 2023

Movie 2. Time-lapse imaging of MDA-MB-231 cells in glucose-depleted medium.
Supplementary Materials from Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells
Authors: Cheng Chun-Ting , Kuo Ching-Ying , Ouyang Ching , Li Chien-Feng , Chung Yiyin , Chan David C. , Kung Hsing-Jien , Ann David K.
Published: April 2023

This file includes supplementary figure legends and movie legends.
Supplementary Figure S3 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Transactivation activity of FLAG-tagged ELF4
Supplementary Figure S13 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: April 2023

Expression level of HRK, DLX3 and MDM2 in head and neck squamous cell carcinoma
Supplementary Figure S3 from STAT3/IRF1 Pathway Activation Sensitizes Cervical Cancer Cells to Chemotherapeutic Drugs
Authors: Walch-Rückheim Barbara , Pahne-Zeppenfeld Jennifer , Fischbach Jil , Wickenhauser Claudia , Horn Lars Christian , Tharun Lars , Büttner Reinhard , Mallmann Peter , Stern Peter , Kim Yoo-Jin , Bohle Rainer Maria , Rübe Christian , Ströder Russalina , Juhasz-Böss Ingolf , Solomayer Erich-Franz , Smola Sigrun
Published: April 2023

HeLa and SW756 cells were stimulated with medium or OSM.
Supplementary Fig 3 from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: April 2023

Late endosomal protein Rab7 also affected following depletion of NRP2 or VEGF-C
Supplementary Methods from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors
Authors: Li Yong , Luo Shunqun , Ma Ruihua , Liu Jing , Xu Pingwei , Zhang Huafeng , Tang Ke , Ma Jingwei , Zhang Yi , Liang Xiaoyu , Sun Yanling , Ji Tiantian , Wang Ning , Huang Bo
Published: April 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplemental Tables and Figures from EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape
Authors: Lim Seung-Oe , Li Chia-Wei , Xia Weiya , Lee Heng-Huan , Chang Shih-Shin , Shen Jia , Hsu Jennifer L. , Raftery Daniel , Djukovic Danijel , Gu Haiwei , Chang Wei-Chao , Wang Hung-Ling , Chen Mong-Liang , Huo Longfei , Chen Chung-Hsuan , Wu Yun , Sahin Aysegul , Hanash Samir M. , Hortobagyi Gabriel N. , Hung Mien-Chie
Published: April 2023

Supplementary Table 1. Relationships between expression of p-PKM2, EGFR and Ki-67 in surgical specimens of triple-negative breast cancer patients. Supplementary Table 2. Relationships between expression of p-PKM2, EGFR and Ki-67 in surgical specimens of non-triple-negative breast cancer patients. Supplementary Figure S1. EGF signaling enhances aerobic glycolysis in TNBC cells. Supplementary Figure S2. PKM2 is a novel binding partner of EGFR and its activity is inhibited by EGFR via Tyr phosphorylation. Supplementary Figure S3. EGFR reprograms cancer cell metabolism by PKM2 phosphorylation in TNBC cells. Supplementary Figure S4. Upregulation of HK2 expression by EGF signaling also contributes to aerobic glycolysis in TNBC cells. Supplementary Figure S5. Glycolysis metabolite, F1,6BP, binds directly to and enhances the activity of EGFR. Supplementary Figure S6. The combination of EGFR and glycolysis inhibitors synergistically suppresses TNBC cell proliferation. Supplementary Figure S7. EGF signaling-induced lactate inhibits cytotoxic T cell activity in TNBC cells.
Supplemental material from The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling
Authors: Mansour Mariam , Haupt Sue , Chan Ai-Leen , Godde Nathan , Rizzitelli Alexandra , Loi Sherene , Caramia Franco , Deb Siddhartha , Takano Elena A. , Bishton Mark , Johnstone Cameron , Monahan Brendon , Levav-Cohen Yarra , Jiang Yong-Hui , Yap Alpha S. , Fox Stephen , Bernard Ora , Anderson Robin , Haupt Ygal
Published: April 2023

Supplemental material
Supplementary Methods and Tables from Peptide–Drug Conjugate GnRH–Sunitinib Targets Angiogenesis Selectively at the Site of Action to Inhibit Tumor Growth
Authors: Argyros Orestis , Karampelas Theodoros , Asvos Xenophon , Varela Aimilia , Sayyad Nisar , Papakyriakou Athanasios , Davos Constantinos H. , Tzakos Andreas G. , Fokas Demosthenes , Tamvakopoulos Constantin
Published: April 2023

Supplementary Methods 1 - Overall Synthesis of sunitinib analogues (SAN1-SAN5) Supplementary Methods 2 - Computational analysis Supplementary Methods 3 - Synthesis of the conjugate SAN1GSC Supplementary Methods 4 - Biochemical Tyrosine Kinase Assay Supplementary Methods 5 - Cellular autophosphorylation assay Supplementary Methods 6 - Overall phenotypic health evaluation and monitoring of body weight Supplementary Methods 7 - Cardiotoxicity studies Supplementary Methods 8 - Blood toxicity Table S1 - List of GST- fusion proteins Table S2 - List of Antibodies
Supplementary Figure S4 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: April 2023

The activity of gluconeogenesis and aerobic glycolysis predicted survival in patients with HCC.
Supplemental Table S2 from JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis
Authors: Li Na , Dhar Shilpa S. , Chen Tsai-Yu , Kan Pu-Yeh , Wei Yongkun , Kim Jae-Hwan , Chan Chia-Hsin , Lin Hui-Kuan , Hung Mien-Chie , Lee Min Gyu
Published: April 2023

ChiP primer sequences.
Supplemental Table S1 from JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis
Authors: Li Na , Dhar Shilpa S. , Chen Tsai-Yu , Kan Pu-Yeh , Wei Yongkun , Kim Jae-Hwan , Chan Chia-Hsin , Lin Hui-Kuan , Hung Mien-Chie , Lee Min Gyu
Published: April 2023

RT-PCR Primer Sequences.
Supplementary Figures 1-5 from Establishment and Characterization of an In Vitro Model of Ovarian Cancer Stem-like Cells with an Enhanced Proliferative Capacity
Authors: Ishiguro Tatsuya , Sato Ai , Ohata Hirokazu , Ikarashi Yoshinori , Takahashi Ryou-u , Ochiya Takahiro , Yoshida Masayuki , Tsuda Hitoshi , Onda Takashi , Kato Tomoyasu , Kasamatsu Takahiro , Enomoto Takayuki , Tanaka Kenichi , Nakagama Hitoshi , Okamoto Koji
Published: April 2023

Supplementary Fig. S1. Spheroid cells derived from human ovarian cancer show characteristics of CSCs. Supplementary Fig. S2. High levels of ALDH activity are associated with CSC-related characteristics. Supplementary Fig. S3. ALDH activity is required for SOX2 expression and proliferation of ovarian CSCs. Supplementary Fig. S4. ALDH1A1 mediates SOX2 expression and proliferation of ovarian CSCs. Supplementary Fig. S5. Feedback regulation by ALDH1A1 and SOX2 for the proliferation of ovarian CSCs.
Figures S1-S7 from Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates β-Catenin Signaling and Tumorigenesis in Multiple Cancer Types
Authors: Chartier Cecile , Raval Janak , Axelrod Fumiko , Bond Chris , Cain Jennifer , Dee-Hoskins Cristina , Ma Shirley , Fischer Marcus M. , Shah Jalpa , Wei Jie , Ji May , Lam Andrew , Stroud Michelle , Yen Wan-Ching , Yeung Pete , Cancilla Belinda , O'Young Gilbert , Wang Min , Kapoun Ann M. , Lewicki John , Hoey Timothy , Gurney Austin
Published: April 2023

Supplemental figures include the RSPO gene expression analysis for CRC models, the in vitro testing of anti-RSPO antibodies on RSPO-negative tumors, the IHC analysis of anti-RSPO3+chemo-treated ovarian tumors, the LGR, ZNRF3, and RNF43 gene expression profile in therapy responsive and non-responsive PDXs, the in vivo resistance of RSPO-negative tumors to RSPO blockade, the analysis of CSC frequency in anti-RSPO3-treated NSCL and pancreatic PDXs, and the IHC detection of CD44 in anti-RSPO3-treated CRC tumors.
Suppl. Figure 7 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: April 2023

Characteristics of ABC-11/CHR-r
Supplemental Data from Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes
Authors: McGrath John P. , Williamson Kaylyn E. , Balasubramanian Srividya , Odate Shobu , Arora Shilpi , Hatton Charlie , Edwards Thomas M. , O'Brien Thomas , Magnuson Steven , Stokoe David , Daniels Danette L. , Bryant Barbara M. , Trojer Patrick
Published: April 2023

Includes Supplementary Methods, Supplementary Tables and Figures and References Supplementary Figure 1: Structure and enzyme inhibitory activity of the KDM1A tool compounds. Supplementary Figure 2: CETSA shows thermal stabilization of KDM1A in intact cells following treatment with active KDM1A inhibitors. Supplementary Figure S3: Effects of RN-1 treatment on colony formation in methylcellulose. Supplementary Figure 4: KDM1A inhibition effects on the RUNX1-RUNX1T1 containing cell line SKNO-1. Supplementary Figure 5: Lack of global changes in histone H3K4 and H3K9 methylation following KDM1A inhibition. Supplementary Figure 6: KDM1A inhibitors affect KDM1A chromatin binding pattern in SKNO-1 cells. Supplementary Figure 7: Treatment of leukemia cells with a combination of KDM1A inhibitor RN-1 and EZH2 inhibitor CPI-169 leads to a synergistic cell killing in AML cell lines.
Figure S2 from Molecular Pathology of Patient Tumors, Patient-Derived Xenografts, and Cancer Cell Lines
Authors: Guo Sheng , Qian Wubin , Cai Jie , Zhang Likun , Wery Jean-Pierre , Li Qi-Xiang
Published: April 2023

Figure S2. The relationship between number of unique genes and number of pairwise DEGs in the TCGA dataset.
Supplementary Figure S10 from Oncogenic Mutation of AIMP2/p38 Inhibits Its Tumor-Suppressive Interaction with Smurf2
Authors: Kim Dae Gyu , Lee Jin Young , Lee Ji-Hyun , Cho Ha Yeon , Kang Beom Sik , Jang Song-Yee , Kim Myung Hee , Guo Min , Han Jung Min , Kim Seong-Jin , Kim Sunghoon
Published: April 2023

Predicted positioning of tRNA synthetases that interact with AIMP2 in MSC.
Figure S5 from A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Authors: Hubert Christopher G. , Rivera Maricruz , Spangler Lisa C. , Wu Qiulian , Mack Stephen C. , Prager Briana C. , Couce Marta , McLendon Roger E. , Sloan Andrew E. , Rich Jeremy N.
Published: April 2023

Wide-field mosaic image of SOX2 and OLIG2 immunofluorescence in an IN528 organoid.
Figure S1 from A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Authors: Hubert Christopher G. , Rivera Maricruz , Spangler Lisa C. , Wu Qiulian , Mack Stephen C. , Prager Briana C. , Couce Marta , McLendon Roger E. , Sloan Andrew E. , Rich Jeremy N.
Published: April 2023

Organoid formation by human 4121 CSCs and genetically engineered mouse RCAS-GFAP-tva/PDGFB glioma cells.
Supplementary Table S1 from Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones
Authors: Ren Yi A. , Mullany Lisa K. , Liu Zhilin , Herron Alan J. , Wong Kwong-Kwok , Richards JoAnne S.
Published: April 2023

Summary of sequencing data on human mucinous ovarian tumor samples.
Supplementary Table S5 from An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells
Authors: Peitzsch Claudia , Cojoc Monica , Hein Linda , Kurth Ina , Mäbert Katrin , Trautmann Franziska , Klink Barbara , Schröck Evelin , Wirth Manfred P. , Krause Mechthild , Stakhovsky Eduard A. , Telegeev Gennady D. , Novotny Vladimir , Toma Marieta , Muders Michael , Baretton Gustavo B. , Frame Fiona M. , Maitland Norman J. , Baumann Michael , Dubrovska Anna
Published: April 2023

Regulation of the genes involved in WNT signaling pathway in the ALDH+ population of DU145 radioresistant (RR) cells versus ALDH- population of DU145 RR cells.
Supplemental Table 1 from Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk
Authors: Patel Yesha M. , Park Sunghim L. , Han Younghun , Wilkens Lynne R. , Bickeböller Heike , Rosenberger Albert , Caporaso Neil , Landi Maria Teresa , Brüske Irene , Risch Angela , Wei Yongyue , Christiani David C. , Brennan Paul , Houlston Richard , McKay James , McLaughlin John , Hung Rayjean , Murphy Sharon , Stram Daniel O. , Amos Christopher , Le Marchand Loïc
Published: April 2023

List of 251 globally significant associations (p < 5E-8) for CYP2A6 in the MEC Cohort
Supplementary Table-1 from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Supplemental Table 1. Sequences of the siRNA oligonucleotides
Supplementary Figure Legend from PTK6 Inhibition Suppresses Metastases of Triple-Negative Breast Cancer via SNAIL-Dependent E-Cadherin Regulation
Authors: Ito Koichi , Park Sun Hee , Nayak Anupma , Byerly Jessica H. , Irie Hanna Y.
Published: April 2023

Figure legend for supplementary figures
Supplementary Figure S3 from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

Interfering with receptor dimerization by mean of decoy MET severely affects receptor endocytosis
Supplementary Figure S1 from Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody
Authors: Pupo Emanuela , Ducano Nadia , Lupo Barbara , Vigna Elisa , Avanzato Daniele , Perera Timothy , Trusolino Livio , Lanzetti Letizia , Comoglio Paolo M.
Published: April 2023

JNJ-605 blocks MET endocytosis triggered by HGF or DO24. MvDN30 does not induce MET internalization
Supplemental Figure Legends from Evidence Implicating Immunological Host Effects in the Efficacy of Metronomic Low-Dose Chemotherapy
Authors: Shaked Yuval , Pham Elizabeth , Hariharan Santosh , Magidey Ksenia , Beyar-Katz Ofrat , Xu Ping , Man Shan , Wu Florence T.H. , Miller Valeria , Andrews David , Kerbel Robert S.
Published: April 2023

Legends for Supplemental Figures S1-S6.
Supplementary Materials and Methods from Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
Authors: Kim So-Youn , Ebbert Katherine , Cordeiro Marilia H. , Romero Megan M. , Whelan Kelly A. , Suarez Adrian A. , Woodruff Teresa K. , Kurita Takeshi
Published: April 2023

Supplementary materials and methods.
Supplementary Figure Legends from Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
Authors: Kim So-Youn , Ebbert Katherine , Cordeiro Marilia H. , Romero Megan M. , Whelan Kelly A. , Suarez Adrian A. , Woodruff Teresa K. , Kurita Takeshi
Published: April 2023

Supplementary Figure Legends
Supplementary Figure 1. Individual participant meta-analysis of body mass index (per 5 kg/m2) and liver cancer risk in the Liver Cancer Pooling Project from Body Mass Index, Waist Circumference, Diabetes, and Risk of Liver Cancer for U.S. Adults
Authors: Campbell Peter T. , Newton Christina C. , Freedman Neal D. , Koshiol Jill , Alavanja Michael C. , Beane Freeman Laura E. , Buring Julie E. , Chan Andrew T. , Chong Dawn Q. , Datta Mridul , Gaudet Mia M. , Gaziano J. Michael , Giovannucci Edward L. , Graubard Barry I. , Hollenbeck Albert R. , King Lindsey , Lee I.-Min , Linet Martha S. , Palmer Julie R. , Petrick Jessica L. , Poynter Jenny N. , Purdue Mark P. , Robien Kim , Rosenberg Lynn , Sahasrabuddhe Vikrant V. , Schairer Catherine , Sesso Howard D. , Sigurdson Alice J. , Stevens Victoria L. , Wactawski-Wende Jean , Zeleniuch-Jacquotte Anne , Renehan Andrew G. , McGlynn Katherine A.
Published: April 2023

Results from individual participant meta-analysis of BMI. Multivariable models include age, sex, study, alcohol, smoking, and race.
Supplementary Figure 2 from Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
Authors: Kim So-Youn , Ebbert Katherine , Cordeiro Marilia H. , Romero Megan M. , Whelan Kelly A. , Suarez Adrian A. , Woodruff Teresa K. , Kurita Takeshi
Published: April 2023

EGFP was detected in the oocytes of all follicle classes in Cre+ ovaries after PD5.
Supplementary Figure 1 from Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
Authors: Kim So-Youn , Ebbert Katherine , Cordeiro Marilia H. , Romero Megan M. , Whelan Kelly A. , Suarez Adrian A. , Woodruff Teresa K. , Kurita Takeshi
Published: April 2023

Serum concentrations of ActA in tumor host were significantly higher than those of adult normal female mice (PD65 Cre-).
Supplementary figure legends from CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma
Authors: Walton Josephine , Blagih Julianna , Ennis Darren , Leung Elaine , Dowson Suzanne , Farquharson Malcolm , Tookman Laura A. , Orange Clare , Athineos Dimitris , Mason Susan , Stevenson David , Blyth Karen , Strathdee Douglas , Balkwill Frances R. , Vousden Karen , Lockley Michelle , McNeish Iain A.
Published: April 2023

Legends for supplementary figures
Table S4 from Mathematical Modeling Reveals That Changes to Local Cell Density Dynamically Modulate Baseline Variations in Cell Growth and Drug Response
Authors: Greene James M. , Levy Doron , Herrada Sylvia P. , Gottesman Michael M. , Lavi Orit
Published: April 2023

Apoptosis percentage of cells cultured in paclitaxol under different conditions, with various drug concentrations
Supplemental Material from In Vivo FRET Imaging of Tumor Endothelial Cells Highlights a Role of Low PKA Activity in Vascular Hyperpermeability
Authors: Yamauchi Fumio , Kamioka Yuji , Yano Tetsuya , Matsuda Michiyuki
Published: April 2023

Supplemental Materials and Methods; Supplemental Figure Legend
Supplementary Material and Methods from The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner
Authors: Liu Xiuxia , Chen Leifeng , Ge Jin , Yan Chen , Huang Zixi , Hu Junwen , Wen Chongyu , Li Ming , Huang Da , Qiu Yumin , Hao Haibin , Yuan Rongfa , Lei Jun , Yu Xin , Shao Jianghua
Published: April 2023

Supplementary Material and Methods
Supplementary Materials and Methods from KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis
Authors: Yan Yongmin , LI Zhiwei , Kong Xiangyu , Jia Zhiliang , Zuo Xiangsheng , Gagea Mihai , Huang Suyun , Wei Daoyan , Xie Keping
Published: April 2023

One file in MS word format contains the following information on methods: 1. Flow Cytometric Cell Sorting Analysis; 2. Reverse Transcription and Quantitative Real-Time PCR; 3. Western Blot Analysis; 4. ChIP Assay; 5. Immunocytochemistry; 6. Promoter Activity Analysis; 7. Transient transfection of Plasmids and siRNAs; 8. Cell Scratch-Wound Healing Assay; 9. Cell Invasion Assay; 10. Immunohistochemistry Analysis; 11. Animal Models of Tumorigenesis and Metastasis; 12. SUPPLEMENTAL REFERENCES
Supplementary Figure S1 from The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner
Authors: Liu Xiuxia , Chen Leifeng , Ge Jin , Yan Chen , Huang Zixi , Hu Junwen , Wen Chongyu , Li Ming , Huang Da , Qiu Yumin , Hao Haibin , Yuan Rongfa , Lei Jun , Yu Xin , Shao Jianghua
Published: April 2023

Supplementary Fig. S1 FAT10, eEF1A1, Rpn10, Ub, expression decreased after transfection of the corresponding shRNA plasmids.
Supplementary Figure 5 from Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Authors: Lucenay Kimberly S. , Doostan Iman , Karakas Cansu , Bui Tuyen , Ding Zhiyong , Mills Gordon B. , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Schematic of adipophilin staining pattern
Supplementary Table S2 from Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
Authors: Molenaar Remco J. , Botman Dennis , Smits Myrthe A. , Hira Vashendriya V. , van Lith Sanne A. , Stap Jan , Henneman Peter , Khurshed Mohammed , Lenting Krissie , Mul Adri N. , Dimitrakopoulou Dionysia , van Drunen Cornelis M. , Hoebe Ron A. , Radivoyevitch Tomas , Wilmink Johanna W. , Maciejewski Jaroslaw P. , Vandertop W. Peter , Leenders William P. , Bleeker Fonnet E. , van Noorden Cornelis J.
Published: April 2023

D0, n and Dq values for survival curves from colony-formation assays after IR.
Supplementary Figure 1 from Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Authors: Lucenay Kimberly S. , Doostan Iman , Karakas Cansu , Bui Tuyen , Ding Zhiyong , Mills Gordon B. , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Cyclin E associates with endogenous ACLY in breast cancer cells.
Supplementary Table 2 from HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation
Authors: Sugata Kenji , Yasunaga Jun-ichirou , Kinosada Haruka , Mitobe Yuichi , Furuta Rie , Mahgoub Mohamed , Onishi Chiho , Nakashima Kazutaka , Ohshima Koichi , Matsuoka Masao
Published: April 2023

Primer sets used for quantification of mouse genes
Supplementary Figure legends from Decreased Mitochondrial Mutagenesis during Transformation of Human Breast Stem Cells into Tumorigenic Cells
Authors: Ahn Eun Hyun , Lee Seung Hyuk , Kim Joon Yup , Chang Chia-Cheng , Loeb Lawrence A.
Published: April 2023

Figure legends for Supplementary figures 1, 2, and 3
Supplementary Figure 4 from HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation
Authors: Sugata Kenji , Yasunaga Jun-ichirou , Kinosada Haruka , Mitobe Yuichi , Furuta Rie , Mahgoub Mohamed , Onishi Chiho , Nakashima Kazutaka , Ohshima Koichi , Matsuoka Masao
Published: April 2023

CD103 expression in ATL patients.
Supplementary Figure 3 from HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation
Authors: Sugata Kenji , Yasunaga Jun-ichirou , Kinosada Haruka , Mitobe Yuichi , Furuta Rie , Mahgoub Mohamed , Onishi Chiho , Nakashima Kazutaka , Ohshima Koichi , Matsuoka Masao
Published: April 2023

HBZ did not induce CD103 expression.
Supplementary Figure 1 from Decreased Mitochondrial Mutagenesis during Transformation of Human Breast Stem Cells into Tumorigenic Cells
Authors: Ahn Eun Hyun , Lee Seung Hyuk , Kim Joon Yup , Chang Chia-Cheng , Loeb Lawrence A.
Published: April 2023

Rare and low heteroplasmic mutations frequency and mutation (%) fraction graphs
Supplementary Figure 3 from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Wnt3a attracts PMC migration.
Table S3 from Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis
Authors: Maiuri Ashley R. , Peng Michael , Podicheti Ram , Sriramkumar Shruthi , Kamplain Caitlin M. , Rusch Douglas B. , DeStefano Shields Christina E. , Sears Cynthia L. , O'Hagan Heather M.
Published: April 2023

Process gene ontologies with significant enrichment in the gene sets with differential methylation.
Supplementary Figure 1 from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Ki-67 immunostaining of PMCs and PMC infiltration into OCUM2MD3-inoculated stomach.
Figure S2 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
Authors: Orlacchio Arturo , Ranieri Michela , Brave Martina , Arciuch Valeria Antico , Forde Toni , De Martino Daniela , Anderson Karen E. , Hawkins Phillip , Di Cristofano Antonio
Published: April 2023

Effect of the Pdk1 L155E allele on the incidence of hyperplasia, solid nodules, and carcinomas in male Ptenthyr-/- mice at 60 weeks of age.
Supplementary Figure Legends and Methods from Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression
Authors: Shibata Tomohiro , Watari Kosuke , Izumi Hiroto , Kawahara Akihiko , Hattori Satoshi , Fukumitsu Chihiro , Murakami Yuichi , Takahashi Ryuji , Toh Uhi , Ito Ken-ichi , Ohdo Shigehiro , Tanaka Maki , Kage Masayoshi , Kuwano Michihiko , Ono Mayumi
Published: April 2023

Supplementary Figure Legends and Methods
Supplementary Figures & Tables from RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers
Authors: Irshad Sheeba , Flores-Borja Fabian , Lawler Katherine , Monypenny James , Evans Rachel , Male Victoria , Gordon Peter , Cheung Anthony , Gazinska Patrycja , Noor Farzana , Wong Felix , Grigoriadis Anita , Fruhwirth Gilbert O. , Barber Paul R. , Woodman Natalie , Patel Dominic , Rodriguez-Justo Manuel , Owen Julie , Martin Stewart G. , Pinder Sarah E. , Gillett Cheryl E. , Poland Simon P. , Ameer-Beg Simon , McCaughan Frank , Carlin Leo M. , Hasan Uzma , Withers David R. , Lane Peter , Vojnovic Borivoj , Quezada Sergio A. , Ellis Paul , Tutt Andrew N.J. , Ng Tony
Published: April 2023

Figure S1, Related to Figure 1 FACS and immunofluorescence validation of Lin-CD127+CD90.2+NKP46- gated ILC3 cells Figure S2, Related to Figure 2 ELISA quantification of CXCL13 and CCL21 chemokines levels in conditioned media (CM) obtained from the bone marrow derived MSC cell line (HS-5) and from the breast cancer cell line 4T1.2 cell line is shown. Figure S3, Related to Figure 2 Proliferation assay of ILC3 cells and ELISA quantification of CXCL13 and CCL21 from siRNA transfected MSC cells. Figure S4, Related to Figure 4 CXCR5 expression on MSC cells. Figure S5, Related to Figure 5 Identification of a RORÎ³T+CD127+CD3- ILC3 cells within the tertiary lymphoid structures within breast cancers. Figure S6, Related to Figure 5 Expression of lymphoid chemokine and chemokine receptor genes in breast cancer datasets. Table S1, Related to Figure 5 Table S1: Clinico-pathological characteristics for the METABRIC sample.
Table S1, Figures S1-S11 from Macrophages Promote Circulating Tumor Cell–Mediated Local Recurrence following Radiotherapy in Immunosuppressed Patients
Authors: Rafat Marjan , Aguilera Todd A. , Vilalta Marta , Bronsart Laura L. , Soto Luis A. , von Eyben Rie , Golla Meghana A. , Ahrari Yasaman , Melemenidis Stavros , Afghahi Anosheh , Jenkins Melissa J. , Kurian Allison W. , Horst Kathleen C. , Giaccia Amato J. , Graves Edward E.
Published: April 2023

Table S1 summarizes the patient radiation and chemotherapy conditions. Figure S1 shows that viable tumor cells are recruited to the MFP following RT. Figure S2 shows that tumor cell recruitment is dose dependent. Figure S3 shows tumor growth curves and lung metastasis after RT. Figure S4 confirms CD4+ and CD8+ T cell depletion in BALB/c mice. Figure S5 presents overall mouse health following MFP RT. Figure S6 illustrates that irradiation of normal cells enhances in vitro cancer cell invasion. Figure S7 evaluates CD8+ T cell infiltration in irradiated normal tissues. Figure S8 shows immune cell infiltration following RT in Nu/Nu mice. Figure S9 shows immune cell infiltration kinetics in BALB/c mice. Figure S10 shows that secreted factors from macrophages influence tumor cell invasion and chemotaxis and that blocking these factors results in a decrease in tumor cell recruitment in vivo. Figure S11 evaluates systemic cytokines following RT.
Supplementary Data 1 from Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma
Authors: Poźniak Joanna , Nsengimana Jérémie , Laye Jonathan P. , O’Shea Sally J. , Diaz Joey Mark S. , Droop Alastair P. , Filia Anastasia , Harland Mark , Davies John R. , Mell Tracey , Randerson-Moor Juliette A. , Muralidhar Sathya , Hogan Sabrina A. , Freiberger Sandra Nicole , Levesque Mitchell P. , Cook Graham P. , Bishop D. Timothy , Newton-Bishop Julia
Published: April 2023

Gene lists per immune cell type after successive filtration steps.
Figure S4 from LPA Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response
Authors: Ha Ji Hee , Radhakrishnan Rangasudhagar , Jayaraman Muralidharan , Yan Mingda , Ward Jeremy D. , Fung Kar-Ming , Moxley Katherine , Sood Anil K. , Isidoro Ciro , Mukherjee Priyabrata , Song Yong Sang , Dhanasekaran Danny N.
Published: April 2023

Effect of silencing Rac2 and Rac3 on LPA-stimulated aerobic glycolysis