bluuebunny/crossref_metadata_2025 huggingface dataset:
Developmental Regression Followed by Epilepsy and Aggression: A New Syndrome in Autism Spectrum Disorder?
Authors: Gaitanis John , Nie Duyu , Hou Tao , Frye Richard
Published: June 2023

Autism spectrum disorder (ASD) with regression (ASD-R) involves the loss of previously attained developmental milestones, typically during the first or second year of life. As children age, it is not uncommon for them to develop comorbid conditions such as aggressive behaviors or epilepsy, which can inhibit habilitation in language and social function. In this paper, we hypothesize that aggressive behaviors and epilepsy more commonly develop in patients with ASD-R than in those without a history of regression (ASD-NR). We conducted a retrospective review of non-syndromic patients with ASD over 12 years of age and compared the rates of epilepsy and aggression between ASD-R and ASD-NR patients. Patients with ASD-R, as compared to ASD-NR patients, demonstrated non-significantly higher rates of epilepsy (51.8% vs. 38.1%, p = 0.1335) and aggressive behaviors (73.2% vs. 57.1%, p = 0.0673) when evaluated separately. The rates for combined epilepsy and aggression, however, were statistically significant when comparing ASD-R versus ASD patients (44.5% vs. 23.8%, p = 0.0163). These results suggest that epilepsy with aggression is more common in ASD-R as compared to ASD-NR patients. When considering the impact of epilepsy and aggression on quality of life, these co-morbidities effectively cause a second regression in patients who experienced an earlier regression as toddlers. A larger, prospective trial is recommended to confirm these associations and further define the timeline in which these characteristics develop from early childhood to adolescence.
Banks’ Leverage Evolution: The Case of Commercial Banks
Authors: Piffer Michele
Published: June 2023

This paper used a panel dataset on the post-Basel-I period to compare the evolution of leverage ratios between commercial and investment banks before the 2007 financial crisis. The comparison showed that the quality of the capital base of commercial banks has been deteriorating since well before the 2007 crisis at a much faster pace than that of investment banks. This paper explains why traditional measures of leverage cannot display this phenomenon and proposes the ratio of the book value of assets over tangible common equity as a better measure.
Measurement of Dried Seafloor Massive Sulfides
Authors: Wichmann Malte , Hördt Andreas
Published: June 2023

We carried out spectral-induced polarization (SIP) measurements on a set of dried seafloor massive sulfide samples and compared the results with those obtained with the same samples fully saturated with NaCl solution. We find that the conductivity and polarizability are generally high for both dried and saturated samples, i.e., exhibiting phase shifts in the order of 100 s of mrad and imaginary conductivities up to 1 S/m. Depending on the particular sample, the polarizabilities of the dried samples remain as high as for the saturated samples or are slightly reduced. The high polarizability of dried samples and the fact that polarizability cannot be destroyed by drying are significant observations because most of the existing theories to explain the polarization of mineralized rock assume a pore space filled with an electrolyte. We also found that the often-used agar gel is unsuitable for coupling the dried samples to the electrodes because it releases water into the sample. Coupling with plasticine is a feasible alternative because significantly less fluid is absorbed by the sample when it is incorporated into the sample holder.
Cadmium Sulfide Quantum Dots, Mitochondrial Function and Environmental Stress: A Mechanistic Reconstruction through In Vivo Cellular Approaches in Saccharomyces cerevisiae
Authors: Marmiroli Marta , Birarda Giovanni , Gallo Valentina , Villani Marco , Zappettini Andrea , Vaccari Lisa , Marmiroli Nelson , Pagano Luca
Published: June 2023

Research on the effects of engineered nanomaterials (ENMs) on mitochondria, which represent one of the main actors in cell function, highlighted effects on ROS production, gametogenesis and organellar genome replication. Specifically, the mitochondrial effects of cadmium sulfide quantum dots (CdS QDs) exposure can be observed through the variation in enzymatic kinetics at the level of the respiratory chain and also by analyzing modifications of reagent and products in term of the bonds created and disrupted during the reactions through Fourier-transform infrared spectroscopy (FTIR). This study investigated both in intact cells and in isolated mitochondria to observe the response to CdS QDs treatment at the level of electron transport chain in the wild-type yeast Saccharomyces cerevisiae and in the deletion mutant Δtom5, whose function is implicated in nucleo–mitochondrial protein trafficking. The changes observed in wild type and Δtom5 strains in terms of an increase or decrease in enzymatic activity (ranging between 1 and 2 folds) also differed according to the genetic background of the strains and the respiratory chain functionality during the CdS QDs treatment performed. Results were confirmed by FTIR, where a clear difference between the QD effects in the wild type and in the mutant strain, Δtom5, was observed. The utilization of these genetic and biochemical approaches is instrumental to clarify the mitochondrial mechanisms implicated in response to these types of ENMs and to the stress response that follows the exposure.
Correlation between the Surface Undulation and Luminescence Characteristics in Semi-Polar 112¯2 InGaN/GaN Multi-Quantum Wells
Authors: Sheen Mi-Hyang , Lee Yong-Hee , Jang Jongjin , Baek Jongwoo , Nam Okhyun , Yang Cheol-Woong , Kim Young-Woon
Published: June 2023

Surface undulation was formed while growing InGaN/GaN multi-quantum wells on a semi-polar m-plane (1–100) sapphire substrate. Two distinct facets, parallel to 112¯2 and 011¯1, were formed in the embedded multi-quantum wells (MQWs). The structural and luminescence characteristics of the two facets were investigated using transmission electron microscopy equipped with cathodoluminescence. Those well-defined quantum wells, parallel and slanted to the growth plane, showed distinct differences in indium incorporation from both the X-ray yield and the contrast difference in annular darkfield images. Quantitative measurements of concentration in 011¯1 MQWs show an approximately 4 at% higher indium incorporation compared to the corresponding 112¯2 when the MQWs were formed under the same growth condition.
Terahertz Optical Properties and Carrier Behaviors of Graphene Oxide Quantum Dot and Reduced Graphene Oxide Quantum Dot via Terahertz Time-Domain Spectroscopy
Authors: Song Seunghyun , Kim Hyeongmun , Kang Chul , Bae Joonho
Published: June 2023

Graphene quantum dots (GQDs) with a band gap have been widely applied in many fields owing to their unique optical properties. To better utilize the optical advantages of GQDs, it is important to understand their optical characteristics. Our study demonstrates the optical properties and carrier behaviors of synthesized graphene oxide quantum dot (GOQD) and reduced graphene oxide quantum dot (rGOQD) pellets via Terahertz time-domain spectroscopy (THz-TDS). The complex permittivity and optical conductivity are obtained in the terahertz region, indicating that the optical conductivity of the GOQD is higher than that of the rGOQD. Although rGOQD has a higher carrier density, approximately 1.5-times than that of GOQD, the lower charge carrier mobility of the rGOQD, which is obtained using Drude–Lorentz oscillator model fitting contributes to a decrease in optical conductivity. This lower mobility can be attributed to the more significant number of defect states within the rGOQD compared to GOQD. To the best of our knowledge, our study initially demonstrates the optical property and carrier behaviors of GOQD and rGOQD in the THz region. Moreover, this study provides important information on factors influencing carrier behavior to various fields in which carrier behavior plays an important role.
Vitamins and Human Health: Systematic Reviews and Original Research
Authors: Barker Tyler
Published: June 2023

Vitamins are a group of organic compounds essential to physiological functions in the body [...]
Nutritional Pearls and Pitfalls of Gastrointestinal Diseases
Authors: Bellini Massimo , Lambiase Christian
Published: June 2023

Since ancient times, food has been considered a possible therapy for treating a wide range of diseases [...]
Cascade Amplification of Pyroptosis and Apoptosis for Cancer Therapy through a Black Phosphorous-Doped Thermosensitive Hydrogel
Authors: Wu Qing , Ma Qinghui , Ma Jun , Chen Junpeng , Zhuang Baoding , Yang Shanglin , Liu Jinji , Wen Shunqian
Published: June 2023

Cell pyroptosis has a reciprocal relationship with various cancer treatment modalities such as chemotherapy. However, the tumor microenvironment, characterized by hypoxia, substantially restricts the development and application of tumor therapies that integrate cell pyroptosis. Therefore, the cascade amplification of oxidative stress by interfering with redox homeostasis in tumors may be a promising approach. In this study, black phosphorus (BP) nanosheets and a glutathione peroxidase 4 inhibitor (RSL3) were coloaded into a thermosensitive PDLLA-PEG-PDLLA (PLEL) hydrogel (RSL3/BP@PLEL). Owing to the photothermal property of BP nanosheets, the RSL3/BP@PLEL hydrogel may trigger the release of loaded drugs in a more controllable and on-demand manner. Investigation of the antitumor effect in a mouse liver tumor model demonstrated that local injection of the hydrogel formulation in combination with near infrared laser irradiation could efficiently suppress tumor growth by interfering with the redox balance in tumors. Mechanistic study indicated that the combined treatment of photothermal therapy and glutathione depletion based on this hydrogel efficiently induced cell pyroptosis through both caspase-1/GSDMD and caspase-3/GSDME pathways, thereby triggering the repolarization of tumor-associated macrophages from M2 to M1. Overall, we developed a biocompatible and biodegradable hydrogel formulation for application in combination cancer treatment, providing a new platform for enhancing the efficacy of cancer therapy by amplifying cell pyroptosis and apoptosis.
Space Charge Characteristics and Breakdown Properties of Nanostructured SiO2/PP Composites
Authors: Zhang Guang-Wei , Gao Jun-Guo , Wang Ran , Lee Ting-tai , Schachtely Uwe , Kobayashi Hitoshi , Wang Wei-Wang
Published: June 2023

Polypropylene (PP) has gained attention in the industry as an environmentally friendly material. However, its electrical properties are compromised due to space charge accumulation during operation, limiting its application in high-voltage DC cable insulation. This study investigates the effect and mechanism of SiO2 with a DDS surface hydrophobic treatment on space charge suppression and the electrical properties of PP composites. The PP matrix was doped with SiO2 nanostructures, both with a DDS surface hydrophobic treatment and untreated as a control group. The functional group structure and dispersion of nanostructured SiO2 in the matrix were characterized. The findings reveal that the incorporation of SiO2 nanostructures effectively mitigates charge accumulation in PP composites. However, a high concentration of unsurfaced nanostructures tends to agglomerate, resulting in inadequate space charge suppression and a diminished DC breakdown field strength. Nonetheless, surface treatment improves the dispersion of SiO2 within the matrix. Notably, the composite containing 1.0 wt% of surface hydrophobic SiO2 exhibits the least space charge accumulation. Compared to the base material PP, the average charge density is reduced by 83.9% after the 1800 s short-circuit discharges. Moreover, its DC breakdown field strength reaches 3.45 × 108 V/m, surpassing pure PP by 19.4% and untreated SiO2/PP composites of the same proportion by 24.0%.
Gender-Role Stereotypes in the Bulgarian Family: Cross-Generational Transmission of Gender Attitudes
Authors: Manolov Manol Nikolov , Ivanov Ivan Kirilov , Chavdarova Velislava Atanasova
Published: June 2023

This article reports a representative quantitative and qualitative study covering the entire territory of Bulgaria, related to the analysis of stereotypes regarding male and female roles in the family and in the society. The results of the study indicate that the factor “age” is significant in relation to attitudes towards the social roles of men and women in the modern family, including in relation to domestic violence. The interpretation of the results enabled the formulation of justified conclusions related to changes in attitudes towards the roles of men and women in a dynamic way. The hypothesis was proven that the tensions between them can be more easily overcome through appropriate differentiated measures tailored to the different age groups.
Quality of Mandatory Social Responsibility Disclosure and Total Factor Productivity of Enterprises: Evidence from Chinese Listed Companies
Authors: Ban Qi , Zhu Huiting
Published: June 2023

This study attempts to determine whether improving the quality of mandatory corporate social responsibility (CSR) information disclosure can have a positive impact on a firm’s development. To this end, an empirical analysis is conducted to establish a relationship between the quality of mandatory CSR information disclosure and a firm’s total factor productivity (TFP), using data from A-share listed companies in China over the period 2009–2020. The results show that: (1) Improving the quality of mandatory CSR disclosure leads to a significant increase in a firm’s TFP. (2) By alleviating a firm’s financing constraints and agency costs, the improved quality of mandatory CSR disclosure effectively enhances the firm’s investment efficiency and innovation capacity, leading to higher TFP. This research extends the influence of CSR disclosure on the economic development outcomes of Chinese firms, and provides theoretical guidance for the development and improvement of CSR disclosure mechanisms in emerging economies.
Disinterestedness in the Creative Economy: The Case of the MO Museum in Vilnius
Authors: Kačerauskas Tomas
Published: June 2023

This article examines the idea of disinterestedness using the case of a private MO museum. The philosophical idea of disinterestedness and its reflections in the creative economy are presented. The idea of disinterestedness is explored as a factor of sustainability in economics. The paradoxes as follows related to disinterestedness in general and to the analyzed case in particular are examined. Although disinterestedness covers detachment from any theoretical concepts, it is also an aesthetic concept. Although this is a futile activity from an economic point of view, disinterestedness helps to remain independent from economic fluctuations. Although the founders of the MO Museum do not expect financial benefits, they are characterized by economic thinking in order to balance the museum’s finances. Disinterestedness, although detached from any interests, includes social responsibility for the state of the art, the desire to enrich and educate society, the development of social connections and personal relationships, and the need for interesting activities. Business management requires a broader intention, but art also requires flexible management. This study is important because of the interdisciplinary approach and the aspects of social responsibility and sustainability in business. In addition, this research opens up a new perspective in connecting the idea of disinterestedness not only with the patronage of art but also with the needs of the business itself. The methods used in this article are as follows: analysis of philosophical literature on the topic of disinterestedness and aspects of disinterestedness in the creative economy, a case study that includes interviews with experts (museum founders and director), and their analysis and summarization. The main finding is as follows: disinterestedness in art management and the creative economy is an aspect of economic sustainability that allows both to expand the economic approach and to show its limits.
Current Development Status, Policy Support and Promotion Path of China’s Green Hydrogen Industries under the Target of Carbon Emission Peaking and Carbon Neutrality
Authors: Yang Lei , Wang Shuning , Zhang Zhihu , Lin Kai , Zheng Minggang
Published: June 2023

The green hydrogen industry, highly efficient and safe, is endowed with flexible production and low carbon emissions. It is conducive to building a low-carbon, efficient and clean energy structure, optimizing the energy industry system and promoting the strategic transformation of energy development and enhancing energy security. In order to achieve carbon emission peaking by 2030 and neutrality by 2060 (dual carbon goals), China is vigorously promoting the green hydrogen industry. Based on an analysis of the green hydrogen industry policies of the U.S., the EU and Japan, this paper explores supporting policies issued by Chinese central and local authorities and examines the inherent advantages of China’s green hydrogen industry. After investigating and analyzing the basis for the development of the green hydrogen industry in China, we conclude that China has enormous potential, including abundant renewable energy resources as well as commercialization experience with renewable energy, robust infrastructure and technological innovation capacity, demand for large-scale applications of green hydrogen in traditional industries, etc. Despite this, China’s green hydrogen industry is still in its early stage and has encountered bottlenecks in its development, including a lack of clarity on the strategic role and position of the green hydrogen industry, low competitiveness of green hydrogen production, heavy reliance on imports of PEMs, perfluorosulfonic acid resins (PFSR) and other core components, the development dilemma of the industry chain, lack of installed capacity for green hydrogen production and complicated administrative permission, etc. This article therefore proposes that an appropriate development road-map and integrated administration supervision systems, including safety supervision, will systematically promote the green hydrogen industry. Enhancing the core technology and equipment of green hydrogen and improving the green hydrogen industry chain will be an adequate way to reduce dependence on foreign technologies, lowering the price of green hydrogen products through the scale effect and, thus, expanding the scope of application of green hydrogen. Financial support mechanisms such as providing tax breaks and project subsidies will encourage enterprises to carry out innovative technological research on and invest in the green hydrogen industry.
The Sustainable Human Resource Practices and Employee Outcomes Link: An HR Process Lens
Authors: Elias Aline , Sanders Karin , Hu Jing
Published: June 2023

Sustainable human resource (HR) practices, such as diversity and inclusion, have gained considerable attention in HR research. However, to this point, most of the research has focused on the content of HR practices, rarely considering the HR process perspective. Consequently, the processes that explain the relationships between sustainable HR practices and subsequent employee behavioural outcomes are unclear. In this conceptual paper, we propose a revised process model to explain the effects of sustainable HR practices by building on the Strategic HR process model. We contribute to the sustainable HR literature, the HR process research, and the process model by Wright and Nishii in particular. We conclude the conceptual paper by highlighting future research recommendations.
Numerical Modeling and Design Method for Reinforced Polyvinyl-Alcohol-Engineered Cementitious Composite Beams in Bending
Authors: Fu Qiao-Ling , Kang Shao-Bo , Wang Dan-Dan
Published: June 2023

The polyvinyl-alcohol-engineered cementitious composite (PVA-ECC) is a superior cementitious material when used for tension and flexural loading. The utilization of PVA-ECC in the tension zone can prevent the development of wide cracks and increase the flexural resistance of reinforced PVA-ECC members. In this paper, a nonlinear finite element model is established to simulate the behavior of PVA-ECC beams in bending. In the model, the constitutive models for PVA-ECC in compression and tension are employed by simplifying them as piece-wise linear models, and the bond between the reinforcing bar and PVA-ECC is also considered. The load–deflection curve and failure mode of beams can be obtained from the finite element model. Comparisons between numerical and experimental results show that the developed numerical model can estimate the ultimate load and failure mode of beams with reasonably good accuracy. After evaluating the accuracy of the finite element model, parameter analysis is conducted to investigate the effects of the reinforcement ratio, steel strength grade, and mechanical properties of PVA-ECC on the flexural behavior of reinforced PVA-ECC beams. The numerical results conclude that the effects of reinforcement ratio on the peak load, stiffness, and deflection are obvious while the influence of steel grade is mainly on the peak load. The tensile localization strain of PVA-ECC mainly affects the ductility of the beam. Furthermore, a design method is proposed based on the plane-section assumption to calculate the ultimate load of reinforced PVA-ECC beams, in which the contribution of PVA-ECC to the moment resistance of beam sections is considered. Comparisons between existing design methods and the proposed method indicate that the ultimate load of beams can be predicted more accurately by considering the tensile strength of PVA-ECC in the tension zone.
Spatial Effects of Green Credit on Air Quality: An Empirical Test Based on the Dual Carbon Perspective
Authors: Li Congxin , Sun Xuejia
Published: June 2023

Based on balanced panel data from 30 provinces and cities (excluding Hong Kong, Macao, Taiwan, and the Tibet Autonomous Region) from 2016 to 2020, this article empirically analyses the spatial effect of green credit (GD) on air quality index (AQI) and the regulatory mechanism between them and explores the differences in the impact of GD on AQI by dividing China into regions in terms of geographical distribution, financial development level, and air quality level. The empirical results found that AQI depends on significant spatial characteristics. GD has a significant inverted U-shaped impact on AQI and is currently at the stage of suppressing air quality. The inverted U-shaped impact is more remarkable in the eastern region, in areas with poor financial development, in areas with poor air quality and GD has entered the stage of promoting air quality levels in the eastern regions, and in areas with good financial development. Environmental regulation has a negative moderating effect on the relationship between GD and AQI, which is less pronounced in eastern regions, in areas with poorly financial development, and in areas with better air quality.
CO2 Adsorption Properties of Amine-Modified Zeolites Synthesized Using Different Types of Solid Waste
Authors: Li Shaojie , Jia Shilong , Nagasaka Tetsuya , Bai Hao , Yang Liyun
Published: June 2023

In this study, organic amines were used to modify zeolite NaA and analcime synthesized using fly ash and iron tailing slag as raw materials, respectively, and the adsorption properties of the modified zeolites toward CO2 were determined. We found that when tetraethylenepentamine (TEPA) was used, the modified zeolite NaA and analcime had the highest nitrogen content. The adsorption capacity of the modified zeolite NaA for CO2 was 4.02 mmol/g and that of the modified analcime was 1.16 mmol/g when the adsorption temperature was 70 °C and the CO2 flow rate was 50 mL/min. According to the adsorption isotherm, kinetic, and thermodynamic model fitting, the adsorption surface of the modified zeolite was not uniform, and the CO2 adsorption of the modified zeolites was classified as chemical adsorption. In a mixed atmosphere of 15% CO2/85% N2, the dynamic selection coefficients of the modified zeolite NaA and analcime for CO2 were 3.8942 and 2.9509, respectively; thus, the two amine-modified zeolites had good selectivity for CO2. After five cycles, the adsorption efficiencies of the modified zeolite NaA and modified analcime for CO2 were 92.8% and 89%, respectively. Therefore, the two amine-modified zeolites showed good recycling performance.
Analysis of the Impact of Carbon Emission Control on Urban Economic Indicators based on the Concept of Green Economy under Sustainable Development
Authors: Xie Si , Li Tianshu , Cao Ke
Published: June 2023

With the deepening of the concept of sustainable development, a green economy has become the primary goal of urban development. Therefore, to improve the sustainability and far-reaching development of the urban economy, this work first discusses the concept of sustainable development. Second, the concept of a “green economy” is discussed. Lastly, based on the concept of green economic development, this work studies carbon emissions in Hebei Province, China, and discusses the impact of carbon emissions on the urban economy. On this basis, the impact of carbon intensity and CO2 emissions on economic growth is analyzed by establishing an endogenous growth model and state-space model, thereby revealing the importance of carbon emissions to the economic development of Hebei Province. In the analysis process, sensitivity analysis and a robustness test are also used to verify the reliability and robustness of the model results. Finally, this work summarizes the research conclusions and puts forward relevant policy suggestions, which provide a reference for developing a green economy in Hebei Province. The results reveal that from 1999 to 2020, the average output elasticity of labor, capital, and CO2 in Hebei Province are 0.4002, 0.3057, and 0.2941, respectively. This shows that carbon emissions are essential to Hebei’s economic growth. In other words, Hebei’s economic development mainly depends on enterprises with high carbon emissions. Additionally, in the optimistic case, Hebei’s potential output growth rate will show a downward trend, but will soon rise. This indicates that even under strict carbon emission control, Hebei’s economic growth rate will still pick up based on the support of high-tech. This work not only provides a reference for the development of Hebei’s green economic system, but also contributes to the sustainable development of the urban economy in the future.
An Evolutionary Game Analysis of Shared Private Charging Pile Behavior in Low-Carbon Urban Traffic
Authors: Zhu Lequn , Zhou Ran , Li Xiaojun , Zhang Linlin
Published: June 2023

Choosing new energy vehicles for travel, especially electric vehicles, is an important component of building a low-carbon urban transportation system. However, the charging need of electric vehicle users is still constrained by the unreasonable layout and insufficient supply of public charging piles in cities. Private charging pile sharing, as an alternative policy tool, can play a beneficial role in solving this problem. However, it needs decision-makers in urban transportation to take corresponding measures to promote. This paper constructs an evolutionary game model to study the decision behavior of participants in a private pile-sharing platform. Through numerical simulation analysis, it is found that under most parameter conditions, the government tends to establish a shared charging pile platform based on public interests. Private charging pile owners are influenced by the relationship between the cost of supply modification and revenue, and they tend to join the shared platform when they expect to recover the modification cost. The research conclusions of this paper will provide support for exploring how participants make decisions to maximize overall benefits in the development of low-carbon urban transportation.
Analysis of Spatial and Temporal Variations in Ecosystem Service Functions and Drivers in Anxi County Based on the InVEST Model
Authors: Li Wen , Geng Jianwei , Bao Jingling , Lin Wenxiong , Wu Zeyan , Fan Shuisheng
Published: June 2023

Background: Exploring the spatial and temporal evolution patterns of regional ecosystem service functions and their main drivers can provide effective support for formulating regional ecological conservation policies and coordinating sustainable economic–ecological development. Methods: This study quantifies the service functions of the water production, soil conservation, carbon storage, habitat quality, and net primary productivity (NPP) in the study area based on the Integrated Valuation of Ecosystem Services and Trade-offs (InVEST) model and the Carnegie–Ames–Stanford Approach (CASA) model and constructs a comprehensive index for ecosystem services (CES) based on the analytic hierarchy process (AHP) to reflect the total supply of various ecosystem services spatially and explore the main driving mechanisms of their spatial variation. The main driving mechanisms of the spatial variation were investigated. Results: (1) Water production in the study area from 2010 to 2020 showed a trend of increasing before decreasing, soil retention showed a trend of continuously decreasing, carbon storage and biotope quality showed a trend of decreasing before increasing, and the NPP showed a trend of continuously increasing. (2) The mean CES of the study area from 2010 to 2020 (0.5398, 0.5763, 0.5456) showed a trend of increasing before decreasing. The improvement areas were mainly concentrated in the western, southwestern, and northeastern parts of the study area, and the degraded areas were mainly distributed in the southeast and northwest. (3) The fit of the geographically weighted regression (GWR) was higher than that of the ordinary least squares (OLS) in all the periods, and the main driving factors affecting the spatial variation in the CES were the NDVI and tea plantation area (T-Area). Conclusion: This study constructed the CES model, explored the regional CES spatiotemporal evolution pattern and its main driving mechanism, and provided a reference basis for promoting the high-quality development of specialized tea regions.
Safety Evaluation and Simulation Research of Filling Mining Mine—A Case Study of Jisuo Coal Mine
Authors: Wang Yuqing , Shi Yongkui , Hao Jian
Published: June 2023

With the demand for green mining in coal mines, filling mining is becoming more and more popular, resulting in more complex production systems and more potential safety hazards. Therefore, it is very important to evaluate the safety of filling mining mines and propose improvement measures. Aiming at the safety evaluation method of filling mining mines, this paper innovatively proposes a safety evaluation method based on entropy weight–attribute mathematical theory, which enriches the theoretical research related to the safety evaluation model of filling mining mines. Five secondary indexes and twenty-two tertiary indexes were selected. The weights were determined via the entropy weight method, and then the attribute mathematical theory was used for safety evaluation. The evaluation results show that the safety level of Jisuo Coal Mine is “relatively safe”, and the evaluation results are in good agreement with the actual situation of Jisuo Coal Mine, which verifies the applicability of the attribute mathematical theory. Finally, from the perspective of safety input, the simulation study is carried out by using system dynamics, and the dynamic change rule is analyzed. Additionally, improvement measures for filling mining mine safety are proposed so as to realize the reasonable optimization of resource allocation.
Cluster Analysis Identifies Distinct Patterns of T-Cell and Humoral Immune Responses Evolution Following a Third Dose of SARS-CoV-2 Vaccine in People Living with HIV
Authors: El Moussaoui Majdouline , Desmecht Salomé , Lambert Nicolas , Maes Nathalie , Braghini Joachim , Marechal Nicole , Quintana Céline , Briquet Karine , Gofflot Stéphanie , Toussaint Françoise , Hayette Marie-Pierre , Vermeersch Pieter , Lutteri Laurence , Grégoire Céline , Beguin Yves , Rahmouni Souad , Moutschen Michel , Desmecht Daniel , Darcis Gilles
Published: June 2023

(1) Background: Many vaccines require higher, additional doses or adjuvants to provide adequate protection for people living with HIV (PLWH). Despite their potential risk of severe coronavirus disease 2019, immunological data remain sparse, and a clear consensus for the best booster strategy is lacking. (2) Methods: Using the data obtained from our previous study assessing prospective T-cell and humoral immune responses before and after administration of a third dose of SARS-CoV-2 vaccine, we assessed the correlations between immune parameters reflecting humoral and cellular immune responses. We further aimed at identifying distinct clusters of patients with similar patterns of immune response evolution to determine how these relate to demographic and clinical factors. (3) Results: Among 80 PLWH and 51 healthcare workers (HCWs) enrolled in the study, cluster analysis identified four distinct patterns of evolution characterised by specific immune patterns and clinical factors. We observed that immune responses appeared to be less robust in cluster A, whose individuals were mostly PLWH who had never been infected with SARS-CoV-2. Cluster C, whose individuals showed a particularly drastic increase in markers of humoral immune response following the third dose of vaccine, was mainly composed of female participants who experienced SARS-CoV-2. Regarding the correlation study, although we observed a strong positive correlation between markers mirroring humoral immune response, markers of T-cell response following vaccination correlated only in a lesser extent with markers of humoral immunity. This suggests that neutralising antibody titers alone are not always a reliable reflection of the magnitude of the whole immune response. (4) Conclusions: Our findings show heterogeneity in immune responses among SARS-CoV-2 vaccinated PLWH. Specific subgroups could therefore benefit from distinct immunization strategies. Prior or breakthrough natural infection enhances the activity of vaccines and must be taken into account for informing global vaccine strategies among PLWH, even those with a viro-immunologically controlled infection.
Recent Developments in Human Papillomavirus (HPV) Vaccinology
Authors: Williamson Anna-Lise
Published: June 2023

Human papillomavirus (HPV) is causally associated with 5% of cancers, including cancers of the cervix, penis, vulva, vagina, anus and oropharynx. The most carcinogenic HPV is HPV-16, which dominates the types causing cancer. There is also sufficient evidence that HPV types 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59 cause cervical cancer. The L1 protein, which, when assembled into virus-like particles, induces HPV-type-specific neutralising antibodies, forms the basis of all commercial HPV vaccines. There are six licensed prophylactic HPV vaccines: three bivalent, two quadrivalent and one nonavalent vaccine. The bivalent vaccines protect from HPV types 16 and 18, which are associated with more than 70% of cervical cancers. Prophylactic vaccination targets children before sexual debut, but there are now catch-up campaigns, which have also been shown to be beneficial in reducing HPV infection and disease. HPV vaccination of adults after treatment for cervical lesions or recurrent respiratory papillomatosis has impacted recurrence. Gender-neutral vaccination will improve herd immunity and prevent infection in men and women. HPV vaccines are immunogenic in people living with HIV, but more research is needed on the long-term impact of vaccination and to determine whether further boosters are required.
Smoothed Particle Hydrodynamics Simulations of Porous Medium Flow Using Ergun’s Fixed-Bed Equation
Authors: Alvarado-Rodríguez Carlos E. , Díaz-Damacillo Lamberto , Plaza Eric , Sigalotti Leonardo Di G.
Published: June 2023

A popular equation that is often employed to represent the relationship between the pressure loss and the fluid flow in fluidized or packed granular beds is the Ergun equation, which is an extension of Darcy’s law. In this paper, the method of Smoothed Particle Hydrodynamics (SPH) is used to numerically study the flow field across a rectangular channel partially filled with a porous layer both at the Representative Elementary Volume (REV) scale using the Ergun equation and at the pore scale. Since the flow field can be estimated at the REV scale with a much lower cost compared to the pore scale, it is important to evaluate how accurately the pore-scale results can be reproduced at the REV scale. The comparison between both scales is made in terms of the velocity profiles at the outlet of the rectangular channel and the pressure losses across the clear and porous zones for three different arrays of solid grains at the pore scale. The results show that minimum differences in the flow structure and velocity profiles between the REV and the pore scale always occur at intermediate values of the porosity (ϕ=0.44 and 0.55). As the porosity increases, the differences between the REV and the pore scale also increase. The details of the pressure losses are affected by the geometry of the porous medium. In particular, we find that the pressure profiles at the REV scale match those at the pore scale almost independently of the porosity only when the grains are uniformly distributed in a non-staggered square array.
Mythology in contemporary culture: the experience of understanding of soviet reality
Authors:   independent researcher, Zhigalov A.V.
Published: June 2023

The article deals with the problem of mythological thinking, characteristic of both individuals and society as a whole. As a result of falsifications and speculation by some episodes, the interested persons present the culture of the Soviet period of our country in a negative light. The author, recognizing the importance of the influence of myth on the minds and worldview of people, seeks to analyze the Genesis of the myth and to rethink the attitude to the Soviet culture on the basis of objective facts.
Edukasi Pemanfaatan Rebusan Daun Sirih Sebagai Obat Kumur Dalam Upaya Menjaga Kebersihan Gigi dan Mulut Pada Remaja
Authors: Sayekti Fitria Diniah Janah , Dewangga Vector Stephen , Rofifah Karina Winda , Devi Alvindo Thiananda , Santosa Lingka Elliesia Putri , Putri Sherrin Karina , Ramadhani Yayi Aullia
Published: June 2023

Pemasalahan gigi dan mulut timbul akibat rendahnya perilaku pemeliharaan kesehatan gigi dan mulut. Menurut Riskesdas (2018) penderita penyakit gigi dan mulut pada remaja cukup tinggi, dengan permasalahan gigi dan mulut di perkotaan lebih rendah (57,2%) dibandingkan penduduk perdesaan (58,2%). Salah satu cara menjaga kebersihan gigi dan mulut adalah menggunakan obat kumur. Daun sirih merupakan tanaman obat tradisional yang mengandung berbagai senyawa yang bersifat antibakteri, dan antijamur yang kuat. Penyuluhan bertujuan untuk meningkatkan pengetahuan dalam menjaga kebersihan gigi dan mulut menggunakan obat kumur alami rebusan daun sirih. Sasaran penyuluhan adalah remaja anggota Karang Taruna dukuh Plumbon, Plumbon, Mojolaban, Sukoharjo, Jawa Tengah dilaksanakan secara online, metode ceramah dengan tahap identifikasi, perencanaan, pelaksanaan. Hasil penyuluhan sangat baik dengan presentase kehadiran 80% (20 peserta), antusiasme peserta dibuktikan dengan 11 pertanyaan yang diajukan kepada pemateri. Pada uji non parametrik Wilcoxon hasil nilai pengerjaan pre-test dan post-test menunjukan (p) < 0,05, dapat disimpulkan ada perbedaan yang signifikan antara hasil pre-test dan hasil post-test, dengan peningkatan hasil pengerjaan 15 peserta (75%).
Peningkatan Ekonomi Mandiri Melalui Alih Teknologi Hidroponik Untuk Warga Troso Kecamatan Pecangaan Kabupaten Jepara
Authors: Musyafa Musyafa , Setiawan Muhammad Doni , Lutviani Lutviani
Published: June 2023

Pengabdian kepada masyarakat merupakan salah satu program kerja dalam Kuliah Kerja Nyata (KKN) Tematik 2021 Unisnu Jepara. Program Kerja KKN Tematik 2021 Kelompok 59 ini mengadakan program kerja Pengabdian Kepada Masyarakat dengan mengangkat tema “Peningkatan Ekonomi Mandiri Melalui Alih Teknologi Hidroponik Untuk Warga Troso Kecamatan Pecangaan Kabupaten Jepara”. Di masa pandemic, pembatasan kegiatan masyarakat yang menuntut masyarakat untuk lebih banyak berada di rumah menjadikan alasan masyarakat membutuhkan skill ilmu pengetahuan untuk mengisi kegiatan dan memiliki nilai ekonomis. Dalam hal ini hidroponik menjadi satu solusi karena memiliki Teknik penanaman yang mudah dan efisien dalam penggunaan lahan sederhana di rumah sendiri. Tujuan dari pelatihan ini adalah untuk meningkatkan pengetahuan dan memperkaya skill warga Troso terkait Teknik penanaman sederhana media hidroponik yang memiliki nilai ekonomis bagi keluarga. Metode yang digunakan dalam pelatihan ini adalah; 1) penyuluhan 2) demonstrasi 3) pembuatan instalasi sederhana di lembah alam jepara sebagai media pembelajaran berlanjut. Sehingga antusiasme warga untuk ikut melaksnakan pelatihan ini dapat berlanjut.
David Johnston, fondateur de la manufacture de Bacalan à Bordeaux, adepte de la monarchie de Juillet
Authors: Du Pasquier Jacqueline
Published: June 2023

David Johnston, who was born in 1789 in Bordeaux where he died in 1853, created the manufactory of fine earthenware of Bacalan. He was the mayor of Bordeaux and a strong supporter of the July monarchy (1830) as can be seen on many pieces of ceramics kept at the Museum of Decorative Arts and Design in Bordeaux and at the National Museum in Sèvres.
Le « Déjeuner des nouvelles vues de Saint-Cloud »
Authors: Serrette Renaud
Published: June 2023

From 1841 to 1844, The Sèvres Manufactory completed a porcelain lunch service illustrated with views of the Saint-Cloud park. It was made by the best artists of the manufactory and sold to Queen Marie-Amélie. It was probably used as a diplomatic gift to Morocco. Each piece is adorned with an unusual view of the Park of Saint-Cloud or shows the railway that had been ordered by Louis-Philippe in the middle of this royal estate.
La production de céramique architecturale de la manufacture de Sèvres
Authors: Houssard Emeline
Published: June 2023

The Ceramics Museum at Sèvres keeps a porcelain tile representing a medley of visual cultures. Zhong Kui, a dragon killer, is represented in an unusual manner that induces the analysis of the various ways in which the popular Chinese image was adapted. As an echo to Dutch 17th century « tegels », Zhong Kui stands in the middle of a blank space deprived of any decor where only ornaments in « fleurs de Lys » at each corner of the tile reveal the fusion of esthetic repertoires.
Pratiques et usages de la photographie au sein de la manufacture et du musée de Sèvres au 20e siècle
Authors: Michaud Pauline
Published: June 2023

The importance of photography both in the collections of the Sèvres Manufactory and of the Museum of Ceramics has never been well known. This article highlights three years of research on the use of photography at Sèvres and the study of the collection of pictures gathered throughout the 19th and 20th centuries.
La vente de porcelaines de Sèvres à Londres par Sallandrouze de Lamornaix
Authors: Lachenal-Taballet Lucie
Published: June 2023

Between 1849 and 1853, The Sèvres Manufactory exhibited its productions at the English branch of Charles Sallandrouze de Lamornaix’s (1808 – 1867) company . This article sheds light on the circumstances of the collaboration of a stateowned manufactory with a private manufacturer and the debates that followed about economic and esthetic issues as international exhibitions were muitiplying.
A Farmer's Choice: Which Field to Put That Manure On?
Authors: Stroheim Erich
Published: June 2023

This article discusses a study that explored choice of fields for manure application by livestock feed growers in three northern Colorado counties. Using results from a mail survey, matched pairs of manured and nonmanured fields were analyzed. Among the field characteristics considered, distance from a manure source, expected yield, cost savings through nutrient substitution, and field size were the most significant factors affecting farmers' manure-application choices. Understanding such factors may provide Extension agents with discussion points for influencing farmers to protect water quality and air quality while making their work lives easier and improving their crop yields.
Rainwater Harvesting at the Department of Public Works
Authors: Obropta Christopher , Bakacs Michele , Rector Patricia
Published: June 2023

As part of an urban Extension initiative that focuses on reducing storm water runoff from impervious surfaces, Rutgers Cooperative Extension installed 5,000-gal cisterns at the Department of Public Works (DPW) facilities in Clark Township and the Township of Parsippany-Troy Hills, New Jersey, to harvest rainwater from the rooftops of the garages at these facilities. This project intercepts rooftop runoff before it can carry nonpoint source pollutants from the land surrounding the DPW garages. The harvested rainwater is used to fill street sweepers, wash municipal vehicles, and supply water for a "green car wash" to support volunteer groups.
Participant Comfort with and Application of Inquiry-Based Learning: Results from 4-H Volunteer Training
Authors: Haugen Heidi , Stevenson Anne , Meyer Rebecca
Published: June 2023

This article explores how a one-time training designed to support learning transfer affected 4-H volunteers' comfort levels with the training content and how comfort levels, in turn, affected the volunteers' application of tools and techniques learned during the training. Results of a follow-up survey suggest that the training participants experienced increases in comfort with guiding inquiry-based learning and achieved high levels of application of the tools and techniques presented during the training. The data indicate that providing participants with opportunities during training to experience tools and build skills by practicing techniques helps them more effectively guide learning in the future.
Physical Activity: A Tool for Improving Health (Part 3—Recommended Amounts of Physical Activity for Optimal Health)
Authors: Galloway Patrick , Hongu Nobuko
Published: June 2023

By promoting physical activities and incorporating them into their community-based programs, Extension professionals are improving the health of individuals, particularly those with limited resources. This article is the third in a three-part series describing the benefits of physical activity for human health: (1) biological health benefits of physical activity, (2) mental health benefits of physical activity, and (3) recommended amounts of physical activity for optimal health. Each part of the series is designed to help Extension professionals effectively integrate physical activity into community programs and motivate individuals to maintain an interest in being physically active during and after a program.
Supercharging Chaperones: A Meeting Toolkit for Maximizing Learning for Youth and Chaperones
Authors: Brandt Brian
Published: June 2023

Trip and conference chaperones are a wonderful resource in youth development programs. These well-intended volunteers, many parents of youth participating in the event, want the best experience for the youth but are not necessarily trained in positive youth development. A consequence of this circumstance is that not all chaperones provide the best opportunities for youth learning. Providing a card-based resource kit that allows for flexibility supports chaperones in running event meetings that are fun and engaging and that improve learning of content and development of life skills.