bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhanced Photocatalytic Hydrogen Generation from Methanol Solutions via In Situ Ni/Pt Co-Deposition on TiO2
Authors: Afrin Mst. Farhana , Furukawa Mai , Tateishi Ikki , Katsumata Hideyuki , Uzzaman Monir , Kaneco Satoshi
Published: February 2025

TiO2 is widely utilized as an excellent photocatalyst in energy production. However, its rapid electron and hole recombination confers poor photocatalytic activity. Cocatalysts are essential for increasing photocatalytic efficacy by introducing improved electron transmission and enlarging the active site. Herein, the photocatalytic degradation of aqueous methanol solution to generate hydrogen was studied with the simultaneous in situ deposition of metals (M = Ag, Cu, Ni, Pd, and Pt) on the TiO2 surface. Adding methanol to water and incorporating a bimetallic cocatalyst enhanced hydrogen production by reducing the electron–hole pair recombination. The studied metal ions could be reduced by the conduction band electrons of TiO2 for the in situ simultaneous deposition of metal. The larger work function value of the studied metals favored the Schottky junction formation, which contributed to increasing photocatalytic efficiency. Among these simultaneous metal-deposited photocatalysts, maximal photocatalytic hydrogen production was achieved with NiPt/TiO2. The optimal component was 0.01 wt.% Ni/1.0 wt.% Pt for TiO2. The hydrogen evolution with NiPt/TiO2 was approximately 341 and 1.3 times better than that with pure TiO2 and Pt/TiO2, respectively. A potential reaction pathway for photocatalytic hydrogen production from an aqueous methanol solution over NiPt/TiO2 photocatalyst has also been proposed.
Treatment of Peripheral Vascular Graft Infections with Xenogeneic Grafts—A Single-Center Experience
Authors: Święszek Agnieszka , Kruczek Wiktor , Serafin Michał , Łyko-Morawska Dorota , Urbanek Tomasz , Kuczmik Wacław
Published: February 2025

Introduction: Vascular graft infections (VGEIs) are rare but severe complications in vascular surgery. The choice of reconstruction material following graft removal is critical, particularly for infection prevention. This study evaluates the use of No-React® BioIntegral Surgical Grafts, made from bovine pericardium, in the treatment of VGEIs. Materials and Methods: A retrospective study of 12 patients (mean age 66.5 years; 67% male) treated between 2020 and 2022 was conducted. The follow-up period included in the study extended from the date of the procedure to 30 June 2024. Results: The study observed a 0% reinfection rate, underscoring the anti-infective potential of No-React® grafts. However, in-hospital complications were frequent, affecting six (50%) patients, with sepsis (3; 25%) related to preoperative VGEIs being the most common. Most importantly, in-hospital mortality was notably high (42%), primarily driven by infection-related sepsis. The overall complication rate after discharge was 14%, with only one case of graft occlusion (1/7) observed. Among discharged patients (7; 58%), the three-month survival rate was 71%. In-hospital complications were a predictive factor for overall survival (OS) (HR = 15.88, 95% CI = 1.81–139.47). Conclusions: Xenogeneic No-React® grafts show promise for managing VGEIs, offering low reinfection rates. However, high morbidity and mortality underline the challenges of treating patients with severe VGEIs. Early postoperative complications were a key predictor of OS. Further research is needed to confirm these findings and optimize treatment protocols for VGEIs.
Effects of Progressive Resistance Training After Hip Fracture: A Systematic Review
Authors: Soro-García Pablo , González-Gálvez Noelia
Published: February 2025

Hip fracture presents high morbidity, mortality, and healthcare costs. Some programs have focused on the effect of progressive strength work on post-hip fracture recovery. Therefore, the objective of this systematic review was to understand the effect of a progressive resistance training program on different variables in adults after hip fracture. This review includes randomized controlled trials that apply progressive strength programs in subjects after a hip fracture. The selected databases are PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), and Ebsco. A total of 7 studies were selected after screening. These studies were published between 2005 and 2022. Most of the research included adults over 65 years of age, showing a mean age of 77.80 years. In the majority of cases, the programs are applied between 3 and 12 months post-fracture. The most commonly applied intervention time is 3 months. The intervention time of the programs typically lasts for 3 months and includes 3–4 lower limb exercises involving, mainly hip and knee movements. All the investigations assess functional capacity and nearly all research the strength. It is shown that the intensity of strength work progresses from 60 to 80% of 1RM. Progressive strength training programs in post-hip fracture patients generally show an improvement in functional capacity, strength, balance, walking speed, flexibility, and cardiorespiratory fitness. However, the effects on independence, quality of life, self-reported physical disability, depression, and cognitive ability do not show conclusive results, and there is little research in this regard.
Advanced Approaches to Material Processing in FFF 3D Printing: Integration of AR-Guided Maintenance for Optimized Manufacturing
Authors: Kaščak Jakub , Kočiško Marek , Török Jozef , Gabštur Peter
Published: February 2025

The field of additive manufacturing increasingly demands innovative solutions to optimize material processing, improve equipment efficiency, and address maintenance challenges in high-utilization environments. This study investigates the operation and management of an FFF 3D printing production line comprising eight remotely controlled printers. The system supports custom manufacturing and educational activities, focusing on processing a range of thermoplastics and composite materials. A key contribution of this work lies in addressing the impact of frequent hardware servicing caused by shared use among users. Augmented reality (AR)-guided assembly and disassembly workflows were developed to ensure uninterrupted operations. These workflows are accessible via smart devices and provide step-by-step guidance tailored to specific material and equipment requirements. The research evaluates the effectiveness of AR-enhanced maintenance in minimizing downtime, extending equipment lifespans, and ensuring consistent material performance during manufacturing processes. Furthermore, it explores the role of AR in maintaining the mechanical, thermal, and chemical properties of processed materials, ensuring high-quality outputs across diverse applications. This paper highlights the integration of advanced material processing methodologies with emerging technologies like AR, aligning with the focus on enhancing manufacturing schemes. The findings contribute to improving process efficiency and adaptability in additive manufacturing, offering insights into scalable solutions for remote-controlled and multi-user production systems.
Projecting Barrier Beach Vulnerability to Waves and Sea-Level Rise Under Climate Change
Authors: Sulis Andrea , Antonioli Fabrizio , Atzeni Andrea , Carboni Andrea , Deiana Giacomo , Orrù Paolo E. , Lo Presti Valeria , Serreli Silvia
Published: February 2025

Long-term impacts of sea-level changes and trends in storm magnitude and frequency along the Mediterranean coasts are key aspects of effective coastal adaptation strategies. In enclosed basins such as a gulf, this requires a step beyond global and regional analysis toward high-resolution modeling of hazards and vulnerabilities at different time scales. We present the compound future projection of static (relative sea level) and dynamic (wind-wave) impacts on the geomorphological evolution of a vulnerable sandy coastal plan located in south Sardinia (west Mediterranean Sea). Based on local temporal trends in Hs (8 mm yr−1) and sea level (5.4 mm yr−1), a 2-year return time flood scenario at 2100 shows the flattening of the submerged morphologies triggering the process of marine embayment. The research proposes adaptation strategies to be adopted to design the projected new coastal area under vulnerabilities at local and territorial scales.
Comparative Genomics and Characterisation of the Role of Saccharomyces cerevisiae Respiration in the Fermentation of Chinese Steamed Bread
Authors: Gao Yawen , Guo Yufeng , Pang Jianing , Liu Mingkai , Yuan Tengdan , Wang Qinhong , Liu Jingsheng
Published: February 2025

The genetic composition of Saccharomyces cerevisiae and its various phenotypes during fermentation significantly correlate to the quality of Chinese steamed bread (CSB). However, the systematic correlation between different S. cerevisiae and CSB has not been fully elucidated. Herein, we characterised CSBs prepared with 36 isolates of S. cerevisiae (designated S1–S36) to comparatively evaluate their correlations. CSBs 1, 2, 13, 21, 25 and 33 exhibited suitable total titratable acidity (TTA) values, pH values and large specific volumes. Texture analysis showed that CSBs 1, 25 and 33 exhibited higher springiness and cohesiveness values. CSBs 8, 25 and 33 exhibited low hardness, gumminess and chewiness values. At the micro level, CSBs 1, 25 and 33 showed a loose reticular structure with large holes and in which starch particles wrapped into gluten protein. Fifty-nine volatile flavour compounds belonging to six categories were determined in 10 selected CSBs, and CSBs 1, 25 and 33 contained more flavour and balanced substance categories. In addition, comparative genomic analysis revealed 33 non-synonymous mutations in the three strains with strong fermentation ability (S1, S25 and S33) and the three strains with weak fermentation ability (S18, S20 and S35) involving 19 genes, including: the respiration-related genes COS5, COS8 and COX10; the starch metabolism transcription factor MSS11; the general transcription factor SPT8; the cell aggregation-related gene FLO1 and the transporter gene SEO1. Other genes with different genotypes were also enriched in respiration-related gene ontology terms. These data offer preliminary experimental evidence regarding the application of S. cerevisiae S1, S25 and S33 in fermented foods derived from grains.
Remodeling of Embryo Architecture in Response to Vanadium and Increased Temperatures: From Morphometric to Molecular Changes
Authors: Chiarelli Roberto , Martino Chiara , Scudiero Rosaria , Terenzi Alessio , Geraci Fabiana
Published: February 2025

The study of ecotoxicity induced by vanadium (V) represents an area of increasing interest due to the growing use of V in both the industrial and pharmaceutical areas. This leads to its introduction into water environments, marking a developing problem, especially since rising global temperatures appear to intensify its toxic properties. Cytotoxicological approaches carried out on whole marine embryos represent a valid research tool since they grow directly in contact with the pollutants and are equipped with highly responsive cells to stressors. Here, we discuss the detrimental impact on Paracentrotus lividus sea urchin embryos resulting from the combination of V and higher temperatures, reflecting the effects of climate variation. The results demonstrate the remodeling of embryonic architecture at the morphometric level, revealing developmental delays and anomalies. These malformations involve variations in the total skeletal mass due to the almost total absence of the skeleton, with the exception of small calcareous aggregates. Furthermore, both a modulation in total tissue remodeling enzymatic activities and a variation in the amount of three MMP-like gelatinases (MMP-2, -9, and -14) were observed. This research demonstrates that climate change significantly increases the harmful effects of V, emphasizing the necessity for comprehensive toxicity assessments in environmental evaluations.
A Precipitation-Based Process to Generate a Solid Formulation of a Therapeutic Monoclonal Antibody: An Alternative to Lyophilization
Authors: Koynov Athanas A. , Lin Wei , Bothe Jameson R. , Schenck Luke , Parajuli Bibek , Li Zhao , Ruzanski Richard , Hoffman Natalie , Frank Derek , VanAernum Zachary
Published: February 2025

Lyophilization, or freeze-drying, is the default technique for the manufacture of solid-state formulations of therapeutic proteins. This established method offers several advantages, including improved product stability by minimizing chemical degradation, reduced storage requirements through water removal, and elimination of cold chain dependence. However, the lyophilization process itself presents limitations. It is a lengthy, batch-based operation, potentially leading to product inconsistencies and high manufacturing costs. Additionally, some proteins are susceptible to structural alterations during the freezing step, impacting their biological activity. This paper presents an alternative approach based on the co-precipitation of protein and excipients using an organic solvent. We explore the impact of various processing parameters on the viability of the formulation. We also provide an extensive characterization of proteins reconstituted from precipitated formulations and compare protein stability in solution and in lyophilized and precipitated solid formulations under long-term, accelerated, and stressed storage conditions.
Characteristics of the Chairman of the Board of Directors and Their Impact on Dividend Payments in the Moroccan Stock Exchange
Authors: Louziri Reda , Oubal Khadija
Published: February 2025

This study examines the influence of chairman characteristics on dividend policy within Moroccan firms listed on the Casablanca Stock Exchange, addressing a critical gap in the behavioral finance literature. This research focuses on five key attributes of chairmen—age, gender, nationality, tenure, and founder status—and analyzes their impact on dividend decisions over a 16-year period (2003–2018). A fixed effects panel data model was employed, incorporating six control variables—firm age, growth opportunities, size, board size, female representation, and foreign ownership. The results demonstrate that chairman age and tenure significantly affect dividend policy. Older chairmen are more risk-averse, favoring higher dividend distributions to ensure financial stability, while longer-tenured chairmen tend to retain earnings for aggressive investments, reflecting overconfidence. The other variables—gender, nationality, and founder status—showed no statistically significant effects in this context. This research provides the first empirical evidence on the relationship between chairman characteristics and dividend policy in Morocco. The findings offer valuable insights for investors, analysts, and policymakers in emerging markets, emphasizing the role of leadership traits in corporate financial strategies. By highlighting the importance of behavioral factors, this study enhances understanding of dividend policy determinants in developing economies.
Corruption Control as a Catalyst for Financial Development: A Global Comparative Study
Authors: Küçükçolak Recep Ali , Bozkurt Gözde , İlter Küçükçolak Necla , Ertemel Adnan Veysel , Küçükoğlu Sami
Published: February 2025

This study investigates the impact of anti-corruption efforts on financial development across different economies, using G7 and E7 countries as comparative groups. Recognizing corruption as a barrier to economic growth, the research examines how effective corruption control can enhance the efficiency of the financial sector, foreign direct investment (FDI), and capital market development. The methodology includes panel cointegration tests—namely Pedroni, Kao, and Westerlund tests—alongside fully modified ordinary least squares (FMOLS) and dynamic ordinary least squares (DOLS) estimations to assess the long-term relationships between corruption control and financial development. The findings reveal a statistically significant cointegration relationship, suggesting that anti-corruption measures positively influence financial development in both G7 and E7 countries, albeit more strongly in E7 economies. Specifically, the Westerlund test results, which take cross-sectional dependencies into account, reinforce the robustness of the findings. The study underscores the importance of tailoring anti-corruption policies to each country’s unique economic framework, highlighting that while G7 countries benefit from advanced institutional structures, E7 countries experience more pronounced effects of corruption control on financial development and FDI. These insights contribute to the policy discourse on sustainable economic development by emphasizing the role of governance quality in fostering robust financial systems and attracting international investment.
Online High-Definition Map Construction for Autonomous Vehicles: A Comprehensive Survey
Authors: Lyu Hongyu , Berrio Perez Julie Stephany , Huang Yaoqi , Li Kunming , Shan Mao , Worrall Stewart
Published: February 2025

High-definition (HD) maps aim to provide detailed road information with centimeter-level accuracy, essential for enabling precise navigation and safe operation of autonomous vehicles (AVs). Traditional offline construction methods involve several complex steps, such as data collection, point cloud generation, and feature extraction, but these methods are resource-intensive and struggle to keep pace with the rapidly changing road environments. In contrast, online HD map construction leverages onboard sensor data to dynamically generate local HD maps, offering a bird’s-eye view (BEV) representation of the surrounding road environment. This approach has the potential to improve adaptability to spatial and temporal changes in road conditions while enhancing cost-efficiency by reducing the dependency on frequent map updates and expensive survey fleets. This survey provides a comprehensive analysis of online HD map construction, including the task background, high-level motivations, research methodology, key advancements, existing challenges, and future trends. We systematically review the latest advancements in three key sub-tasks: map segmentation, map element detection, and lane graph construction, aiming to bridge gaps in the current literature. We also discuss existing challenges and future trends, covering standardized map representation design, multitask learning, and multi-modality fusion, while offering suggestions for potential improvements.
Epistemology in the Age of Large Language Models
Authors: Mugleston Jennifer , Truong Vuong Hung , Kuang Cindy , Sibiya Lungile , Myung Jihwan
Published: February 2025

Epistemology and technology have been working in synergy throughout history. This relationship has culminated in large language models (LLMs). LLMs are rapidly becoming integral parts of our daily lives through smartphones and personal computers, and we are coming to accept the functionality of LLMs as a given. As LLMs become more entrenched in societal functioning, questions have begun to emerge: Are LLMs capable of real understanding? What is knowledge in LLMs? Can knowledge exist independently of a conscious observer? While these questions cannot be answered definitively, we can argue that modern LLMs are more than mere symbol-manipulators and that LLMs in deep neural networks should be considered capable of a form of knowledge, though it may not qualify as justified true belief (JTB) in the traditional definition. This deep neural network design may have endowed LLMs with the capacity for internal representations, basic reasoning, and the performance of seemingly cognitive tasks, possible only through a compressive but generative form of representation that can be best termed as knowledge. In addition, the non-symbolic nature of LLMs renders them incompatible with the criticism posed by Searle’s “Chinese room” argument. These insights encourage us to revisit fundamental questions of epistemology in the age of LLMs, which we believe can advance the field.
Mapping and Assessing the Supply and Demand of Rural Recreation Services in National Parks: A Case Study of Qianjiangyuan, Zhejiang, China
Authors: Chen Xiaodong , Wu Chengzhao
Published: February 2025

National parks not only protect natural resources but also provide a variety of cultural ecosystem services, with their rural areas serving as important locations for providing rural recreation services (RRS). Spatial quantification of RRS supply and demand will contribute to ensuring the protection and promotion of human well-being in national parks. In this study, we proposed an integrated framework to map and assess the spatial distribution of RRS supply and demand in Changhong Township, located within Qianjiangyuan National Park. We used a combination of spatial analysis and the MaxEnt model as tools, which played a positive role in saving time when modeling areas providing cultural ecosystem services. Based on the findings, the study area was divided into different zones to propose spatial planning measures. The results showed that (1) the MaxEnt model was robust in mapping RRS supply. RRS supply and demand distribution had high spatial heterogeneity. (2) The proportion of areas where RRS supply exceeded demand was 72.58%, primarily distributed in areas with a high level of naturalness at the periphery of the study area. (3) This study divided Changhong Township into four types of zones: developed recreation service area, potential recreation service area, recreation service demand area, and marginal recreation service area. We proposed suggestions for the scientific utilization and management of RRS in each zone. Overall, our findings provide a scientific basis for planning rural recreation spaces within national parks, promoting the comprehensive utilization of rural cultural ecosystem services.
Remotely Sensed Spectral Indices as Proxies of the Structure of Urban Bird Communities
Authors: Kontsiotis Vasileios J. , Chatzigiovanakis Stavros , Valsamidis Evangelos , Nalmpantis Eleftherios , Xofis Panteleimon , Liordos Vasilios
Published: February 2025

Abundant and diverse urban bird communities promote ecosystem and human health in cities. However, the estimation of bird community structure requires large amounts of resources. On the other hand, calculating remotely sensed spectral indices is cheap and easy. Such indices are directly related to vegetation cover, built-up cover, and temperature, factors that also affect the presence and abundance of bird species in urban areas. Therefore, spectral indices can be used as proxies of the structure of urban bird communities. We estimated the abundance, taxonomic, functional, and phylogenetic diversity of the bird community at each of 18 50 m radius survey stations in the urban core area of Kavala, Greece. We also calculated eight spectral indices (means and standard deviations, SDs) around survey stations at 50 m, 200 m, and 500 m spatial scales. The land surface temperature SD (LST) was the most important proxy, positively related to bird abundance at the 50 m and 200 m spatial scales. At the same time, the mean green normalized difference vegetation index (GNDVI) was the most important proxy, negatively related to abundance at the 500 m spatial scale. Means and SDs of vegetation indices, such as the normalized difference vegetation index (NDVI), enhanced vegetation index (EVI2), soil-adjusted vegetation index (SAVI), and atmospherically resistant vegetation index (ARVI), were the most important proxies, positively related to taxonomic and functional diversity at all the spatial scales. The mean and SDs of LST, normalized difference moisture index (NDMI), and normalized difference built-up index (NDBI) variously affected taxonomic and functional diversity. The mean and SDs of LST were the best proxies of phylogenetic diversity at the 50 m and 500 m spatial scales, while the SDs of NDBI and NDMI were the best proxies at the 200 m spatial scale. The results suggest that several spectral indices can be used as reliable proxies of various facets of urban bird diversity. Using such proxies is an easy and efficient way of informing successful urban planning and management.
Trends, Atmospheric Patterns, and Spatial Variability of Heatwaves in an Oceanic Climate Area of NW Iberia
Authors: Pérez-García Luis , García-Hernández Cristina , Ruiz-Fernández Jesús
Published: February 2025

In the Atlantic region of northern Spain, heat extremes were historically rare, but in recent decades, they have become more intense and persistent. This article characterizes heat events in Asturias (NW Spain) between 2001 and 2023, focusing on their frequency, intensity, and duration, as well as their temporal trends. Additionally, it explores the synoptic patterns linked to these episodes to enhance understanding of their occurrence and evolution over the study period. The research is based on official meteorological records, and it distinguishes between officially declared heatwaves (DHs) and significant heat events (SHEs) identified through regional press reports. This methodology enables the study to capture a broader spectrum of heat-related impacts. During the study period, 17 episodes were documented (11 DHs and 6 SHEs). The frequency, intensity, and duration of heat events have significantly increased, particularly since 2016, standing the last two years (2022 and 2023). Both DHs and SHEs have progressively shifted toward the early and late periods of the astronomical summer, with some events occurring during spring and autumn in the second half of the study period (years 2017, 2022, and 2023). Three atmospheric patterns have been identified as responsible for extreme heat episodes; Type 1 (warm tropical continental air masses, combined with atmospheric stability) is responsible for 10 of the episodes. Furthermore, urban areas and main river valleys were the most affected areas, while coastal regions remained largely unaffected. This research aims to contribute to a broader understanding of how heatwaves are evolving in a temperate climate area under the influence of global warming, providing insights to inform and improve adaptation strategies for mitigating their impacts.
The Atypicality of Predicates with Two Explicit Arguments in Indonesian Conversation
Authors: Ewing Michael C.
Published: February 2025

While transitive clauses with a subject and object have long been a fundamental focus of grammatical analyses across languages of the world, more recently, it has become apparent that naturally occurring language-in-use is in fact overwhelmingly intransitive and transitive clauses with two arguments have a relatively low frequency. In this study, I examine conversational Indonesian and focus on one construction type, a transitive predicate with two explicit core arguments. This grammatical configuration is considered atypical due to its very low frequency in conversational interaction. The goal of the study is to begin to understand when and why expressions of this type appear. It is found that these atypical configurations regularly occur at points where there is a change in footing, including changes in topic, participation framework, or referentiality. It is further shown that the contrast between explicit and unexpressed arguments in Indonesian conversational grammar contributes to the reasons why predicates elaborated with two arguments tend to appear when there is a change in footing.
What Is New in Psychiatry and Psychopharmacology
Authors: Marazziti Donatella
Published: February 2025

Psychiatry and psychopharmacology are rapidly evolving due to the developments in different domains and the constantly increasing demands for psychiatric care worldwide amongst children, adolescents, adults, and elderly populations, who all require specific and tailored management and treatment strategies [...]
Personality and Its Influence on Pain Sensitivity Based on Different Hormonal Responses to Individual vs. Group Exercise Styles
Authors: Nakae Aya , Bu-Omer Hani M. , Kishimoto Chie , Chang Wei-Chuan , Sumioka Hidenobu
Published: February 2025

Individual differences in pain sensitivity are thought to relate to personality traits, but the underlying mechanisms remain unclear. Exercise influences hormonal secretion via the hypothalamic–pituitary system, which may link personality, hormonal responses, and pain perception. This study investigated these relationships in 14 healthy participants (3 females, 11 males, aged 20–50 years, mean 28 ± 9.25 years). Participants rated thermal pain stimuli and completed the NEO Personality Inventory-Revised (NEO-PI-R) to identify their personality. Each participant engaged in personal and group training sessions, with blood samples collected to measure cortisol, growth hormone, and other indicators. Participants were clustered into cortisol hypersecretors and hyposecretors based on their hormonal response. Hypersecretors exhibited significantly lower neuroticism scores and pain ratings than hyposecretors. These findings suggest a potential association between cortisol responsiveness during exercise, neuroticism, and pain sensitivity. This study highlights potential links between personality traits and reactive hormonal patterns, offering insights into the psychophysiological mechanisms underlying pain expression.
Fabrication of Network Spherical α-Al2O3 and Its Application on the Separator of Lithium-Ion Batteries
Authors: Chen Haiyang , Zhang Huifang , Huang Hongliang , Guo Mingjie , Wang Jiale , Wang Peng , Li Bin , Chen Junhong
Published: February 2025

Ceramic-coated polyolefin separator technology is considered a simple and effective method for the improvement of lithium-ion battery (LIB) safety. However, the characteristics of ceramic powder can adversely affect the surface structure and ion conductivity of the separators. Therefore, it is crucial to develop a ceramic powder that not only improves the thermal stability of the separators but also enhances ion conductivity. Herein, network spherical α-Al2O3 (N-Al2O3) with a multi-dimensional network pore structure was constructed. Furthermore, N-Al2O3 was applied as a coating to one side of polyethylene (PE) separators, resulting in N-Al2O3-PE separators that exhibit superior thermal stability and enhanced wettability with liquid electrolytes. Notably, the N-Al2O3-PE separators demonstrated exceptional ionic conductivity (0.632 mS cm−1), attributed to the internal multi-dimensional network pore structures of N-Al2O3, which facilitated an interconnected and efficient “highway” for the transport of Li+ ions. As a consequence, LiCoO2/Li half batteries equipped with these N-Al2O3-PE separators showcased remarkable rate and cycling performance. Particularly at high current densities, their discharge capacity and capacity retention rate significantly outperformed those of conventional PE separators.
Comparative Study of the Tensile Properties of a Zircaloy-4 Alloy Characterized by Mesoscale and Standard Specimens
Authors: Dong Ruohan , Zhao Ning , Tong Shenghui , Zhang Zeen , Li Gang , You Zesheng
Published: February 2025

The accuracy and reliability of small-scale mechanical tests remain doubtful due to significant dependence of the obtained mechanical properties on specimen size. Mesoscale tensile tests with specimen sizes ranging from 10 μm to 1 mm are capable of obtaining bulk-like properties but are rarely applied to hexagonal close-packed metals. In this study, well-designed comparative tensile tests were carried out on a Zircaloy-4 alloy with a grain size of 4 μm using femtosecond laser-machined mesoscale specimens with a thickness of about 60 μm, sub-sized specimens with a thickness of about 1.3 mm, and standard specimens with a thickness of 4 mm. The quantitative results revealed that irrespective of the small specimen dimensions, the yield strength, tensile strength, and tensile ductility are only approximately 10.4%, 5.2%, and 13% lower than those of the standard specimens, respectively. This clearly demonstrates that the mechanical properties can be assessed with satisfactory accuracy by mesoscale tensile tests. The comparatively greater deviation of the yield strength at the mesoscale arises from the disappearance of yield point behavior, while the reduced tensile ductility is associated with the larger volume fraction of surface grains. The surface grains are characterized by more surface dislocation sources and deform with weaker constraints from neighboring grains, leading to smooth plastic yielding and slightly reduced strain hardening at the mesoscale.
Processing and Characterisation of Alumina/Eucryptite Nanostructured Composites
Authors: Inocente Jordana Mariot , da Costa Renata Bochanoski , Mattos Ana Sônia , Alcázar Carmen , Borrell Amparo , Moreno Rodrigo , Arcaro Sabrina , Montedo Oscar Rubem Klegues
Published: February 2025

Alumina is one of the most studied and used ceramic materials, but increasing its fracture toughness is still a challenge for many specific impact applications. Adding a second phase with a low coefficient of thermal expansion (CTE) to an alumina matrix can enhance the matrix’s mechanical properties, reduce its sintering temperature, and increase its toughness by generating compressive stresses on the alumina particle surface. In this study, nanostructured alumina/eucryptite composites were prepared to achieve enhanced toughness. First, eucryptite (Li2O·Al2O3·2SiO2) nanoparticles were successfully synthesised via colloidal heterocoagulation. These nanoparticles were then used to reinforce alumina matrices through slip casting followed by conventional sintering. Complete crystallisation of eucryptite was achieved at 850 °C with a CTE of 0.46 × 10 −6 °C −¹. Transmission electron microscopy analysis revealed that the average particle size was 28.5 ± 14.5 nm. To achieve a relative density of 95.3%, the composite containing 5 vol.% eucryptite required sintering for 1 h at 1400 °C whereas pure alumina required 2 h at 1600 °C. This reduction in sintering temperature (by up to 200 °C) helped to improve the fracture toughness, with the alumina grain size decreasing from 2.3 to 0.9 µm. The advantages of the new composite are the more economically viable and environmentally friendly way of producing the lithium aluminosilicate nanoparticles, compared to the production of ceramic frits at high temperatures (~1500 °C).
Application of Magnetic-Assisted Polishing Using Metal-Bonded Grinding Wheels for Machining Silicon Nitride Ball Bearings
Authors: Han Su-Yeon , Lee Seung-Min , Kim Ha-Neul , Ko Jae-Woong , Kwak Tae-Soo
Published: February 2025

Silicon nitride (Si3N4) is used for high-speed rotating bearings in machine tools, aircraft, and turbo pumps due to its excellent material properties such as high-temperature strength, hardness, and fracture toughness. Grinding with fixed abrasives enables high shape accuracy and high efficiency in machining brittle materials. However, it is difficult to completely remove surface damage, which limits its use in products requiring a nano surface. These defects also result in reduced reliability and shortened lifespan. Magnetic-assisted polishing (MAP) is a technology that can achieve a fine surface by using a mixture of iron powder and abrasives, but it requires a lot of time due to the low material removal rate (MRR). Therefore, this study developed a hybrid processing technology using a metal-bonded grinding wheel and a slurry with hard abrasives for the high precision of silicon nitride ceramic ball bearings. Experiments were conducted in order to compare and analyze the surface roughness and material removal rate. Through MAP, using a grinding wheel with low grit (#325), high-efficiency machining performance was confirmed with a maximum material removal rate of 1.193 mg/min. In MAP, using a grinding wheel with high grit (#2000), a nano-level surface roughness of 6.5 nm Ra was achieved.
Ranking of Autonomous Technologies for Sustainable Logistics Activities in the Confectionery Industry
Authors: Božić Mladen , Dabić-Miletić Svetlana , Andrejić Milan , Djurdjević Dragan
Published: February 2025

The food supply chain (FSC) faces significant challenges, including the short shelf life of products, stringent food safety standards, and the growing demand for online ordering. These challenges underscore the need for a resilient and sustainable FSC, particularly in the confectionery industry, which is further burdened by the demand for innovative and healthier products. The aim of this paper is to optimize material handling activities in warehouse operations within the confectionery industry by ranking and selecting adequate material handling equipment (MHE). This paper proposes a novel hybrid multi-criteria decision-making model that integrates the Simple Aggregation of Preferences Expressed by Ordinal Vectors Group Decision Making (SAPEVO-M), Fuzzy Analytic Hierarchy Process (FAHP), and Fuzzy COmprehensive distance-Based Ranking (FCOBRA) methods. The model was applied to a real-world case study involving four alternative solutions and twelve defined evaluation criteria. The application of the model identified the implementation of an Automated Guided Vehicle system (AGVs) as the optimal alternative, offering substantial automation of logistics activities and addressing identified company challenges. The engagement of AGVs is estimated to reduce operational costs by 20%, improve warehouse operation efficiency by 30%, and decrease CO2 emissions by 25%. The contribution of this paper lies in the development of a methodological framework for evaluating and selecting MHE, as well as in highlighting the importance of optimizing material handling processes in the confectionery industry.
Containment Control for High-Order Heterogeneous Continuous-Time Multi-Agent Systems with Input Nonconvex Constraints
Authors: Xu Jiahao , Wang Yaozhong , Zhang Wenguang
Published: February 2025

This article investigates containment control for high-order heterogeneous continuous-time multi-agent systems (MASs) with input nonconvex constraints, bounded communication delays and switching topologies. Firstly, we introduce a scaling factor for the constraint operator to obtain an equivalent unconstrained system model. Following equivalent model transformations, we analyze the maximum distance from all agents to the convex hull spanned by leaders using norm-based differentiation. It is demonstrated that, within high-order heterogeneous continuous-time MASs subject to control input nonconvex constraints, the convergence of each agent into the convex hull spanned by leaders is guaranteed, provided that there exists at least one directed path from any leader to each agent within the union of communication topologies. Simulation examples are presented to validate the theoretical findings.
Muscle Strength and Cardiovascular Health in MASLD: A Prospective Study
Authors: Kumbaroğlu Birgül Fatma , Balaban Yasemin Hatice , Düger Tülin
Published: February 2025

Background and Objectives: The pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) remains incompletely understood. However, recent studies highlight the interactions between muscle, liver, and adipose tissue. This study aimed to explore the relationships between clinical indicators of MASLD and sarcopenia, cardiorespiratory fitness, fatigue, and mood. Materials and Methods: The study involved 60 participants, including 28 healthy controls and 32 with MASLD, categorized into two disease subgroups: 15 with MASL and 17 with metabolic dysfunction-associated steatohepatitis (MASH). Participants completed an incremental speed shuttle walk test to evaluate cardiorespiratory fitness, a hand-held dynamometer assessment for appendicular muscle strength, and the timed up and go test for physical performance. Physical activity level, fatigue, quality of life, and emotional state were assessed using questionnaires. The test results were compared between groups and with disease characteristics. Results: MASL and MASH groups showed reduced cardiorespiratory fitness (p < 0.001). The knee extensors were significantly weaker in both MASL and MASH groups (p < 0.001 and p = 0.001, respectively). The MASH group reported higher levels of depression and negative health perception (p = 0.006 and p = 0.03, respectively). Muscle strength in patients with MASLD showed a significant negative association with depression (OR = −0.384, 95% CI: −3.10 to −0.74, p = 0.003), intrahepatic triglyceride content (OR = −0.287, 95% CI: −1.31 to −0.11, p = 0.023), and LDL (OR = −0.286, 95% CI: −0.02 to −0.33, p = 0.03). In contrast, a positive association was observed between VO2 and muscle strength (OR = 0.531, 95% CI 1.27 to 3.47, p < 0.001). Conclusions: This study suggests that muscle strength is linked to key metabolic parameters, such as hepatic fat, LDL levels, and aerobic capacity, that may contribute to the development and progression of MASLD. Interventions aimed at preserving or enhancing muscle strength in MASLD patients may be essential for preventing liver damage and improving metabolic health.
Immunohistochemical Expression of Differentiated Embryonic Chondrocyte 1 and Cluster of Differentiation 44 in Oral Potentially Malignant Disorders
Authors: Onofrei Bianca-Andreea , Ciobanu Apostol Delia Gabriela , Tanasă Mădălina-Gabriela , Baciu Elena-Raluca , Popa Cristina , Sciuca Ana Maria , Toader Mihaela Paula , Costan Victor-Vlad
Published: February 2025

Background and Objectives: Oral cancer remains a critical global health concern, with oral squamous cell carcinoma (OSCC) being the most prevalent form. Oral potentially malignant disorders (OPMDs), such as oral leukoplakia (OLK), oral lichen planus (OLP), and actinic cheilitis (AC), often precede OSCC. Identifying reliable biomarkers is vital for assessing malignant transformation risk. The present study aimed to evaluate the immunohistochemical expression of differentiated embryonic chondrocyte 1 (DEC1), a marker of dysplasia severity, and cluster of differentiation 44 (CD44), which is associated with cancer progression, in OPMD and OSCC tissues. Materials and Methods: A retrospective analysis was conducted on 145 biopsy specimens from January 2015 to January 2023, comprising normal mucosa (NM), OLK, OLP, AC, and OSCC. DEC1 and CD44 expression levels were assessed using immunohistochemical staining. Positivity scores were determined based on staining intensity and extent, with statistical analyses performed using SPSS software (SPSS Inc., Chicago, IL, USA, version 29.0 for Windows). Results: It was found that CD44 expression significantly increased across OPMD and OSCC compared to NM (p < 0.001). Conversely, DEC1 expression was consistent across lesion types and dysplasia levels. CD44 expression was the highest in AC and OSCC, underscoring its potential role as a progression marker. Conclusions: The results indicate that CD44 is a more sensitive marker for assessing dysplastic severity and malignant transformation, while DEC1 may serve as a complementary marker for early-stage evaluation. Further research involving larger cohorts is needed to confirm these findings.
Assessment of Women’s Awareness of the Possible Risk of Stroke Associated with the Use of Oral Contraceptives Pills in Saudi Arabia: A Cross-Sectional Study
Authors: Edris Fawaz E. , Alasiri Rehab Ahmed A. , Albukhari Abdullah Faisal , Sadiq Mohammed Arab , Alahmadi Wojood Mubarak , Alruwaili Alhanouf Radhyan , Alhadidi Nojuod Fares , Alenezi Iman Hamid , Sabban Hussein Talal , Gari Abdulrahim , Eskandar Mamdoh , Salma Umme , Alshaikh Ahmed Baker A.
Published: February 2025

Background and Objectives: One of the most widely used reversible contraceptive techniques among women of reproductive age worldwide is oral contraceptives (OCPs). Despite their widespread use, OCPs are associated with increased risks of stroke, yet the extent of awareness of these risks among women remains insufficiently explored. This study aims to evaluate the level of awareness among women resident in Saudi Arabia regarding the potential risk of stroke linked to the use of OCPs. Materials and Methods: A cross-sectional descriptive study was conducted targeting women of reproductive age (18–49 years). Data was collected through an online self-administrated questionnaire distributed via social media platforms, encompassing sociodemographic characteristics, OCP usage patterns, and awareness of stroke risks, perceived side effects of OCPs, symptoms of stroke, and methods to reduce stroke incidence. Statistical analysis was performed using SPSS version 23, with descriptive statistics for categorical data and chi-square tests to assess associations. Results: A total of 516 women participated in the study. Of these, 148, or over a quarter (28.7%), of the participants reported using oral contraceptive pills; 86, or more than half (58%), who use OCPs are not sure what type of OCPs they use; 60, or over half of the participants (40.5%), have been using for less than a year. Over two thirds of the participants (350, 67.8%) are not aware that using OCP increases the risk of stroke. The most recognized side effect of OCPs use was weight gain (38.2%), while awareness of stroke as a side effect was significantly lower (24.6%). Additionally, 62.8% of respondents identified selecting the appropriate type of contraceptive as the best way to prevent stroke while taking OCPs. Conclusions: this study highlights the need for increased awareness and education about the potential risk of cerebral thrombosis associated with OCP use among Saudi women. Addressing this knowledge gap through targeted educational initiatives could help mitigate the risks and improve overall public health outcomes.
Optical Coherence Tomography Angiography Flow Signal in Non-Treatment-Naïve Patients with Neovascular Age-Related Macular Degeneration Treated with Faricimab
Authors: Brinkmann Max , Müller Tom , Köster Marco , Schweighofer Jakob , Danckwardt Mathis , Giannaccare Giuseppe , Marolo Paola , Borrelli Enrico , Reibaldi Michele , El-Shabrawi Yosuf , Toro Mario Damiano
Published: February 2025

Background and Objectives: Age-related macular degeneration (AMD) remains a leading cause of legal blindness. Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for neovascular AMD (nAMD). The choroid plays a key role in AMD and is affected by the anti-VEGF treatment. Faricimab, a bispecific antibody additionally targeting angiopoietin 2 (Ang2), was recently approved for nAMD treatment. This study investigates the effect of Faricimab on choroidal flow signal. Materials and Methods: Optical coherence tomography angiography images of 29 nAMD eyes were examined retrospectively. Patients had received treatment with other anti-VEGF agents before Faricimab application. The flow signal in the choroid was measured before, after one and after a series of ≥2 Faricimab injections. Results: The flow signal decreased significantly (p = 0.026) at the choriocapillaris (CC) level after ≥2 injections. The flow signal did not show a significant change in Haller’s layer but increased slightly in Sattler’s layer (p = 0.034). Conclusions: In conclusion, our results show that the flow signal, especially at the CC level, changed during treatment. Despite the known influence of anti-VEGF treatment on the choroid, auxiliary inhibition of Ang2 might enhance this effect. Due to the retrospective nature, moderate sample size and non-treatment, naïve patients, care must be taken while interpreting our observations. Prospective studies with larger sample sizes and treatment-naïve patients will be needed.