bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostic significance of myocardial and multimodal contrast exercise stress echocardiography in the detection of hemodynamically significant coronary artery stenosis in stable angina pectoris
Authors: Koretsky S. N. , Mirgorodskaya O. V. , Vasyuk Yu. A. , Drapkina O. M.
Published: May 2023

Aim. To evaluate the diagnostic significance of myocardial contrast stress echocardiography (MCSE) and multimodal contrast stress echocardiography (MMSE) with dosed exercise in detecting hemo­dynamically significant coronary artery stenosis in patients with stable coronary heart disease (CAD) without impaired regional left ventricular contractility at rest.

Material and methods. MCSE and MMSE were performed in 61 pa­­tients with suspected or stable CAD (mean age, 62,9±8,9 years). All patients underwent coronary angiography. During MCSE, perfusion and regional contractility were assessed. With MMSE, regional contractility was assessed. Sensitivity, specificity, and positive (LR+) and negative (LR-) likelihood ratios for MCSE and MMSE were assessed in com­parison with coronary angiography.

Results. The sensitivity of MCSE with perfusion assessment was 82% (CI, 67-92%) with specificity of 70% (35-92%), LR+ — 2,74, LR- — 0,26. Sensitivity of MCSE with assessment of perfusion and regional contractility was 67% (50-81%) with specificity of 90% (65-99%), LR+ — 6,67, LR- — 0,37. The sensitivity of MCSE with an estimate of regional contractility of 74% (58-87%) with a specificity of 90% (56-98%), LR+ — 7,4, LR- — 0,28. The sensitivity of MMSE in the mode of cavitary and myocardial contrasting was 72% (55-85%) with a specificity of 90% (56-99%), LR+ — 7,18, LR- — 0,31.

Conclusion. MCSE with an assessment of regional contractility and MMSE are of diagnostic importance in the detection of CAD, a positive result of which increases the post-test probability of hemodynamically significant coronary artery stenosis. A positive result of MCSE with dosed exercise with isolated perfusion assessment does not have a diagnostically significant effect on the post-test probability of CAD.
Circulating biological markers of obesity: towards a systems approach
Authors: Timofeev Yu. S. , Dzhioeva O. N. , Drapkina O. M.
Published: May 2023

The pathological processes associated with obesity are based on impaired energy homeostasis, as well as excessive endocrine and paracrine activity of adipose tissue, leading to inflammation and hormonal imbalance, which is accompanied by the secretion of a wide range of compounds affecting key body processes. One of the indirect methods for assessing the adipose tissue abnormalities is the measurement of the concentration of cytokines, growth factors, as well as a class of specific compounds — adipokines specific to adipose tissue. The study of circulating biomarkers makes it possible to assess their association with the risk of complications, metabolic obesity, and other clinical and functional features. Such markers include adipokines (leptin, adiponectin, apelin, resistin, omentin, visfatin, chemerin, lipocalin, etc.), inflammation biomarkers, heat shock proteins, which are discussed in detail in this review in the context of their use in obesity and concomitant diseases.
APPLICATION OF DIESEL-RK SIMULATION TOOL FOR REDUCING NOX EMISSION FROM BIODIESEL BLEND FUELS AT RETARDED INJECTION CONDITION
Authors: Pal Manas Kumar , Reddy E. Ramakrishna
Published: May 2023

In renewable energy resources, although biodiesels have occupied the top place as an alternative for compression ignition engines, their high NOx discharge causes concern. Retarded fuel injection is a probable solution to reduce NOx emission. In the present work, tests are conducted with corn seed methyl ester (CSME) blend at standard and retarded fuel injection timings. Improvement in brake thermal efficiency and reduction in NOx emissions are observed due to the retardation of fuel injection timing. DIESEL-RK engine simulation software is used as a potential tool to simulate retardation conditions, and simulation results are compared with experimental values. It is seen that along with the performance and combustion parameters, the simulated NOx emission results are in good agreement with experimental values. Hence, the modeling used in the DIESEL-RK software captures the experimental observations well.
ENGINE PERFORMANCE OF NEEM SEED OIL BIO-DIESEL WITH PENTANOL BLEND IN DIESEL ENGINE USING SIMPLEX-LATTICE DESIGN FOR OPTIMIZATION
Authors: Sulaiman Adamu , Umar Umar Ali , Kaisan Muhammad Usman , Ibrahim Ibrahim Umar , Abubakar Shitu , Nathaniel Oyedeji Ayodeji
Published: May 2023

Fossil fuel engine emissions are a well-known environmental and health hazard. The present study explores a novel approach to mitigating emissions by blending pentanol and biodiesel produced from Neem seed oil with pure diesel to address this issue. The blend consists of 70% pure diesel and 30% biodiesel/pentanol, with pentanol concentrations ranging from 3-12% by volume. The resulting mixtures are labelled according to their biodiesel and pentanol content (B27P3, B24P6, B21P9, and B18P12). To determine the optimal blend, a simplex-lattice design optimization is performed. The results indicate that the blend containing 25.39 vol.% neem seed oil biodiesel and 4.61 vol.% pentanol demonstrates the best engine emission properties. Moreover, the study shows that adding pentanol to the diesel-neem seed oil biodiesel blend significantly improves engine performance. Therefore, the results suggest that diesel-biodiesel-alcohol blends hold promise as a potential alternative fuel source.
Determinants of iron deficiency and anemia among Nunavimmiut: results from the Qanuilirpitaa? 2017 Nunavik Health Survey
Authors: Lavoie Audrey , Lemire Mélanie , Lévesque Benoit , Ayotte Pierre
Published: May 2023

Objective

To estimate the prevalence of iron deficiency (ID) and anemia and study their main distal and proximal protective and risk factors among Nunavimmiut 16 years and older in 2017.

Methods

In a cross-sectional participatory survey of 831 women and 436 men from the Qanuilirpitaa? 2017 Nunavik Inuit Health Survey, venous blood samples were collected to measure various indicators of iron status and anemia as well as biomarkers of nutritional and inflammatory status and contaminant exposures. Sociodemographic, food security status, anthropometric, lifestyle, dietary, and health data were collected using questionnaires, clinical sessions, and a medical chart review. ID and anemia diagnoses were based on serum ferritin (SF) and hemoglobin (Hb), respectively. Multiple regressions were used to assess correlates of anemia and iron status.

Results

Prevalence of ID was highest among women of childbearing age (16–49 years old, 33%) and anemia among adults aged 50 years and older (31%). These estimates are prone to biases due to the relatively low participation rate (37%). Serum vitamin D, omega-3 polyunsaturated fatty acid content of erythrocyte membranes, blood selenium, inflammation, higher socioeconomic status (SES), obesity, and alcohol consumption were all positively associated with SF, while Helicobacter pylori infection and a recent pregnancy were negatively associated with Hb among women of childbearing age. Among older adults, food insecurity was associated with lower SF.

Conclusion

While data reported here provide some indication of an improvement since the previous survey conducted in 2004, additional efforts should be devoted to further increasing the SES and access to country foods and nutritious market foods in this population, the two main protective factors against ID and anemia identified in the present study.
How does traditional chinese medicine treat attention deficit hyperactivity disorder-A different understanding and treatment strategy
Authors: Sai Zhao , Yuanxiong Deng , Zijia Chen , Sumei Wang
Published: May 2023

Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder, and the incidence in children is increasing year by year. The modern medical field lacks long-acting drugs for the treatment of ADHD and there is an urgent need to investigate new therapeutic drugs or complementary and alternative therapies. Recent studies have found that Traditional Chinese Medicine (TCM) has the advantages of individualization, precise efficacy and minimal side effects in improving attention deficit hyperactivity disorder. This paper reviews the progress of Chinese medicine in the treatment of ADHD in terms of its understanding of the etiology and pathogenesis of ADHD, treatment according to pattern identification and Chinese medicinal preparations.
DNA quantification with PicoGreen v1
Authors: Székely Anna
Published: May 2023

We use the Quant-iT™ PicoGreen® dsDNAkit for quantification of both extracted and amplified DNA. The Quant-iT™ PicoGreen® dsDNA reagent is a proprietary, asymmetrical cyanine dye. Free dye does not fluoresce, but upon binding to dsDNA it exhibits a >1000-fold fluorescence enhancement. PicoGreen is 10,000-fold more sensitive than UV absorbance methods, and highly selective for dsDNA over ssDNA and RNA. For moreinformation see: https://www.thermofisher.com/order/catalog/product/P7589
Online Survey Among Pregnant Women With Medical Indication Or Wish For Elective Caesarean Section On Second Opinions In Germany: Study Protocol v1
Authors: Könsgen Nadja
Published: May 2023

Background: Caesarean section (CS) rates have been continuously rising worldwide over the last decade without being accompanied by significant health benefits. Various approaches are discussed internationally to limit the proportion of caesarean deliveries to the necessary cases. The proposed study aims to assess the perspective of pregnant women with medical indication or wish for elective CS on second opinions The goal is to examine whether they consider a second opinion useful to facilitate their decision-making and/or certainty for the mode of delivery, and under which circumstances they would seek a second opinion. Methods: The study population will comprise adult pregnant women (18 years or older) with medical indication or wish for elective CS (both currently pregnant women and persons for whom the indication was given in a past pregnancy). The survey will be conducted online and the data will be evaluated using quantitative descriptive analysis. Discussion: The survey is an opportunity to get a comprehensive picture from the perspective of pregnant women. In combination with our survey of health professionals it paves the way for following research in this area.The results might be limited by a possible selection bias of the study population.
Ancient DNA protocol collection – University of Tartu, Institute of Genomics v1
Authors: Keller Marcel
Published: May 2023

Ancient DNA protocols from sampling to library preparation for shotgun Illumina sequencing - aDNA lab UTIG. All protocols except the indexing PCR and purification need to be performed in a dedicated ancient DNA laboratory (see guidelines). The individual steps are respective protocols are: 1. Sampling 1.a tooth roots 2. Decontamination of samples (optional) 3. Ancient DNA extraction 3.a high volume (chunk samples) 4. Purification of DNA extracts 6. Library preparation 6.a dsDNA, double indexing, non-UDG, 2x split 6.b dsDNA, single indexing, non-UDG 6.c dsDNA, double indexing, full-UDG, 2x split 6.d dsDNA, single indexing, full-UDG 7. Indexing PCR and purification
Community Support Organizations in Gay Neighborhoods: Assessing Engagement During the Covid-19 Pandemic
Authors: Hess Daniel Baldwin , Bitterman Alex
Published: May 2023

Volunteerism, grassroots activism, and mutual aid have been critical to the advancement of rights and opportunities for LGBTQ+ people. These activities are institutionally anchored within supportive organizations embedded in LGBTQ+ communities. But these supportive organizations can be stressed by external crises, such as the Covid-19 pandemic, limiting the capacity for providing routine services. This article provides a typology of community support organizations—including healthcare providers, business improvement districts, neighborhood planning organizations, and social groups and clubs—to better understand how non-governmental organizations and non-profit entities provide services not traditionally provided by government agencies for LGBTQ+ people. We characterize how community support organizations continued to provide critical services to the LGBTQ+ community—consistent with the missions and aims of these organizations—while also providing services and information related to health and safety during the Covid-19 pandemic. The article concludes with takeaway messages that synthesize the functions and services of community support organizations and explain how various types of supportive organizations in gay neighborhoods responded to the Covid-19 pandemic.
Internet of Things and Competitive Advantage: A Dynamic
Capabilities Perspective
Authors: Sullivan Yulia ,   Baylor University, Wamba Samuel Fosso ,   TBS Business School, Dunaway Mary ,   Morgan State University
Published: May 2023

Internet of Things (IoT) is one of the enabling technologies of Industry 4.0. Although IoT has shown
great promise for organizations, its practical use in generating value alone or in combination with
existing IT capabilities remains unclear. Drawing upon the literature on dynamic capabilities and
innovation capability, we propose IoT-enabled innovation capability (IoT-IC), consisting of three
dimensions (IoT use for sensing, seizing, and reconfiguring) to explain competitive advantage. We
examine three ordinary IT capabilities (flexible IT infrastructure, IT business experience, and
relationship infrastructure) as the predictors of IoT-IC. We also test the moderating effect of
competitive aggressiveness in influencing the relationship between IoT-IC and competitive advantage.
Analysis of survey data from 175 U.S. companies provides empirical support for our research model.
The results suggest that flexible IT infrastructure, IT business experience, and relationship
infrastructure are positively associated with IoT-IC. Furthermore, the effect of IoT-IC on competitive
advantage is positively moderated by competitive aggressiveness. The results point to the important
role of existing IT capabilities in shaping IoT-IC and expand our understanding of the relationship
between IoT-IC and competitive advantage at different levels of competitive aggressiveness.
Contextualizing Team Adaptation for Fostering Creative Outcomes in Multicultural Virtual Teams: A Mixed Methods Approach
Authors: Shirish Anuragini ,   Université Paris-Saclay, Univ Evry, IMT-BS, LITEM, Srivastava Shirish C. ,   HEC Paris, Boughzala Imed ,   Université Paris-Saclay, Univ Evry, IMT-BS, LITEM
Published: May 2023

Rapid developments in real-time collaborative technologies, coupled with the quest for innovation
and creativity, have made global virtual teams (GVTs) a viable workplace collaboration option that
many companies are turning to. Although diverse team member perspectives in GVTs are expected
to foster creativity, cultural diversity within GVTs also poses significant challenges related to
knowledge exchange and integration among team members. Grounding our work in the team
adaptation and cultural intelligence (CQ) literatures, we suggest CQ as a plausible modality for
cultural adaptation in GVTs. Specifically, we propose a nomological network comprising CQ
dimensions (motivation, cognition, metacognition, and behavior) serving as a cultural adaptation
mechanism for fostering creativity in GVT outcomes. We contextualize and extend CQ theory, which
has previously focused on face-to-face contexts, to the virtual collaborative GVT environment. For
this, we conceptualize the significant role of deep-level implicitly negotiated adaptative behavior
(role structure adaptation) in GVTs—in addition to surface-level explicitly displayed adaptative
behavior (CQ behavior). We tested the proposed model through a sequential mixed methods
approach that integrated the results from a quantitative two-wave survey study with findings from a
qualitative study comprising expert interviews, to arrive at rich and robust inferences and metainferences. The proposed CQ-for-GVT framework, along with delineated boundary conditions and
associated propositions, explicates an integrative model explaining the role of CQ for GVT creativity
performance. The delineated model not only has theoretical implications but also provides useful
directions for GVT practitioners.
CHURCH AND THE COVID-19 PANDEMIC IN UKRAINE: VACCINATION AS A CHALLENGE
Authors:   Lesya Ukrainka Volyn National University, Lutsk, Ukraine, Boreiko Yuriі , Kulakevych Mykhailo ,   Lesya Ukrainka Volyn National University, Lutsk, Ukraine, Fedotova Tetiana ,   Lesya Ukrainka Volyn National University, Lutsk, Ukraine
Published: May 2023

The article examines the attitude of churches and religious organizations in Ukraine and their followers to vaccination against CoViD-19. It was established that immunization is one of the challenges of modern society, which concerns the sphere of religion as the refusal to vaccinate is often explained by religious motives. Churches and religious organizations in Ukraine demonstrate a common position on immunization as a voluntary and informed choice, emphasizing that this issue is within the competence of health professionals. One of the incentives that motivate believers to get vaccinated is the opening of vaccination points at temples. The attitude of believers to vaccination is not due to religious affiliation but to official information about the coronavirus and vaccination, which has a low level of trust.
THE CONCEPT OF THE ROLE OF MONASTICISM IN THE MODERN WORLD BY ECUMENICAL PATRIARCH BARTHOLOMEW І
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Kozar Kateryna
Published: May 2023

The article examines the role of monasticism in the modern world according to the teachings of Ecumenical Patriarch Bartholomew І. Particular attention is paid to current social problems of today, their relationship with the monastic tradition. The article states that the mission of monasticism becomes not only spiritual, but also social, moral and ecological. Some aspects of the Orthodox Church's social doctrine concerning gender issues and the possibilities of the female priesthood are also considered. For the Ecumenical Patriarch, the coverage of apophatic anthropology and theology is necessary to show the integrity of the ideological unity of the Orthodox tradition in matters of human dignity, which is established in Christianity and must be realized in modern times through monasticism. Attention is drawn to the fact that the sacred dimension of the world is closely and deeply connected with the ascetic dimension, where asceticism is the realization and recognition that humanity depends not only on God but also on the world, like any other being. Accordingly, the Orthodox monastic life is not an escape from society, but a special way of self-sufficient social life and behavior based on reasonable consumption, rather than the abuse of material and natural goods.
CULTURAL PRACTICES OF SPACE AND MEMORY: EXPERIENCE OF TOPOGRAPHY AND CULTURAL LANDSCAPE (ON THE MATERIALS OF BABYN YAR HOLOCAUST MEMORIAL CENTER)
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Pavlova Olena
Published: May 2023

The Babyn Yar memorial complex is one of the few Holocaust memorial spaces in Eastern Europe, located on the site of the mass murder of people during the occupation of Kyiv by German troops in 1941-1943, especially the Jewish population. The article presents the study of logic and aesthetics of memorial space with the help of concepts optics of "Symbolic Architecture" (Georg Hegel), "Sublime" (Immanuel Kant), as well as "Greate Tradition" (Robert Redfield, Milton Singer) and "Walking" (Olga Freidenberg). This optic helps to understand the specificity of de-differentiation of the cultural landscape of historical place and symbolic architecture, as well as the augmented reality in the practice of memorial procession and community, which it constructs through the oppositions highlighting of subterranean and terrestrial, visual and audible, whole and fragmented, and symmetrical and shapeless. Spatial forms of cultural memory organization help avoid memorycide outside ideological disputes and Europeanization of Holocaust tragedy images. It can be noted that the tragic events of World War II, which revealed the "Dialectic of the Enlightenment" and the dark side of Modernity in general, led to the need to re-organize the space of cultural memory. There was a lack of only the internalized structures of the subject and only discursive forms of its objectification to preserve and transmit grief of this level of intensity. The Ukrainian experience of visualizing the tragedy of the Holocaust continues the traditional means of symbolic architecture length and monumentality, sublimity. At the same time, the scale of the complex allows to diversify the practices of the image and thus make new connotations in the practice of its memorialization. In particular, a variety of forms of symbolic architecture and augmented reality was a successful technique, which allows to emphasize the status of the procession as a form of cultural memory, as well as to successfully use the landscape of the historical city in the logic of de-differentiation of subterranean and terrestrial, where other forms of syncretism visual and audio integral and fragmented, symmetrical and shapeless – serve as artistic techniques that work to increase the involvement in the space of the memorial actor of cultural memory.
STRATEGIES OF KEEPING OF PLACES OF MEMORY WITHIN CULTURAL HERITAGE STUDIES
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Rohozha Mariya
Published: May 2023

The article is focused on the strategies of keeping the places of memory in the focus of the regime of temporality in the contemporary world. The methodological ground for the research is memory studies based on cultural anthropology, in particular, in collective memory regimes of temporality and "present pasts" cultivating (Assmann), as well as the rethinking of the principle of historicism (Lübbe). That presupposes revealing cultural heritage issues through the theme of places of memory (Nora). The new regime of temporality was provided by tragic experience of humankind during the World War II. Today time comprehension regime trough "present pasts" cultivation provides the new form of cultural memory comprehension. It appeals to space artefacts unlike the Modernity form, which worked with texts. Places of memory are particular, through which universal is refracted in the new regime of temporality. The author argues that intellectual search at the crossroads of history, philosophy and culture studies fixes the new regime of temporality, from the "present futures" to the "present pasts". "Present pasts" actualize genetic relation with the past, in comprehension of which is possible understanding current ourselves. Accents are removed from the history of the great accomplishments to the history of daily routine, and attention is paid on individual traumas and mental wounds in the new regime of temporality. That is why the history of memory with appealing to individual, psychological aspects enter the proscenium of historical studies. The past is set in the form of the cultural heritage in the new regime of temporality. Babyn Yar is the place of memory that represents particular where the universal is refracted in in the new regime of temporality. Strategies of keeping of places of memory represented in the private and the state projects reflect concepts "present futures" and "present pasts", respectively.
RELIGION AND HUMAN RIGHTS IN DISCOURSE AND PRACTICE OF CULTURAL RELATIVISM AND UNIVERSALISM
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Marchenko Andrii
Published: May 2023

The content and features of the coexistence of universal and local (primarily religious) values and approaches to the problem of human rights are considered; the specifics of the contradictory interaction of religious ideas and attitudes and human rights in the discursive and practical dimensions of cultural relativism and universalism have been studied; the features of the vision of universal and local codes of human rights in Islam, Christianity, in particular Catholicism, in the space of the system of "Asian values" are analyzed; the influence of a dialectical interrelationship between the universality of norms in the private sphere and the religious traditional law on the establishment of the fundamental standards of human rights was examined. It is noted that in the modern world there is a desire of some religions (for example, Islam and Christianity) to connect the idea of universalism and the practice of its assertion with their basic principles, which are given an absolute, comprehensive, infallible nature. In this connection, the topic of religious exclusivity is also relevant, where exclusivism is the belief that my faith is the true faith and other beliefs are wrong. On the other hand, the author points to one of the paradoxes of relativism, which is that it sometimes seeks to become universalism or, rather, absolutism, proposing (and often imposing) a system of its values as the only true. The article emphasizes the necessity to value religious differences, as well as to care for other people, regardless of religion, the need and importance of finding a balance between the universalist understanding of human rights and a diverse, multi-confessional world, combining adherence to certain religious traditions with a commitment to the universality of human rights. As a possible option, an attempt to integrate universal values into the body of the corresponding particular religious and cultural traditions is considered, and, on the other hand, the enrichment of universal human rights standards with relevant unique religious and cultural values.
The Osli Formation – a Holocene lithostratigraphic unit in the Danube/Kisalföld Basin, eastern Austria and northwestern Hungary
Authors: Häusler Hermann , Kovács Gábor , Wild Eva Maria , Steier Peter , Heil Bálint
Published: May 2023

In the course of field investigations and formalisation of Quaternary deposits in the Lake Neusiedl/Seewinkel and Hanság area the Osli Formation is designated as new formal lithostratigraphic unit. It covers an area of ~200 square kilometres and, in historic times, wetlands such as swamps and peat bogs extended from Waasen in the south-eastern Seewinkel Plain to the Hanság (Kisalföld). Due to missing stratigraphic data this formation cannot be formally divided into two members but into a lower and upper section instead. The lower section of the Osli Formation was cored in the Seewinkel Plain and consists of lacustrine deposits of up to 10 metres in thickness that were presumably deposited during Preboreal. Despite the draining of the Hanság over centuries and decades of peat mining, the upper section of the Osli Formation nowadays still consists of an at least one-meter-thick succession of peat intercalated with fluvio-lacustrine deposits. The investigated peat layers at Tétényi-Hany (~5 km north of Osli) were 14C-dated, ranging in age from ~2,400 BC to 1,500 AD. 14C ages of peat profiles at Osli-Tőzegbánya (Fövenyes-tó), located ~2,5 km northeast of Osli, even date back to ~4,000 BC. Hence the 10 to 12 m thick Osli Formation can be dated as Holocene. It is underlain by Quaternary deposits of the Illmitz Formation.
From shallow into deep sea: Sedimentary facies and U-Pb zircon ages in the early Paleozoic Noric Group at Veitsch (Eastern Greywacke Zone, Austria)
Authors: Nievoll Josef , Fritz Harald , Gallhofer Daniela , Hauzenberger Christoph , Pfatschbacher Michael , Gritsch Bernadette
Published: May 2023

The low-grade metamorphic early Paleozoic basement of the Veitsch area presents a wide variety of sedimentary facies domains. The first domain consists of thick metadacites of Middle Ordovician age (Blasseneck Porphyroid), overlain by fine-grained metaclastics of the Rad Formation (Late Ordovician to Silurian) and Devonian limestones and calcitic marbles (Kaiserstein and Kaskögerl Formation, respectively). Rhyolitic to dacitic magmatism initiated at ca. 479 Ma (LAMC-ICP-MS U-Pb zircon data) and lasted until ca. 444 Ma. The second domain comprises metaclastics of the Stocker Formation (Early Ordovician to Silurian), characterized by thin volcanics and volcaniclastics of andesitic and rhyolitic composition. U-Pb zircon data give Middle Ordovician age (463 Ma – 468 Ma). The third domain, exposed northwest of Veitsch, consists of thick metadacites (Blasseneck Porphyroid, ca. 478 Ma), followed by (siliceous) phyllites which grade into turbiditic metasediments (Sommerauer Formation, Late Ordovician to Devonian?). Clastic sediments of the Stocker and Sommerauer Formations were sourced from northern Gondwana showing a prominent Pan-African detrital zircon peak at ca. 640 Ma. Middle to Upper Ordovician volcanics (ca. 462 Ma – 448 Ma) represent the second source. Tectonic reconstruction leads us to the arrangement of three facies domains. A shallow marine shelf facies is located in the present days southwest. A marginal basin with volcanic islands on a sloping continent, and a deep-water environment containing turbidites are situated further to the northwest. The present arrangement of these facies domains is explained by eo-Alpine and Variscan thrust tectonics.
A regional scale Cretaceous transform fault zone at the northern Austroalpine margin: Geology of the western Ammergau Alps, Bavaria
Authors: Sieberer Anna-Katharina , Ortner Hugo
Published: May 2023

We reinvestigated parts of the northern Austroalpine margin and provided structural and kinematic field data in order to interpret the kinematic relationship between the Cenoman-Randschuppe (CRS) marginal slice, Falkensteinzug (FSZ), Tannheim- and Karwendel thrust sheets occurring in a narrow strip at the northern front of the northwestern Northern Calcareous Alps (NCA). As a consequence, we propose a revised model for the tectonic evolution of the northern Austroalpine margin. As thrusting propagates from SSE to NNW (Cretaceous orogeny), the Karwendel thrust sheet (including its frontal part, the FSZ) was emplaced onto the Tannheim thrust sheet in the Albian, deduced from (i) upper-footwall deposits, the youngest sediments below the Karwendel thrust (Tannheim- and Losenstein Fms.), and (ii) thrust-sheet-top deposits unconformably overlying the deeply eroded northern Karwendel thrust sheet (Branderfleck Fm.). The future CRS marginal slice was, at that time, part of the foreland of this Early Cretaceous Alpine orogenic wedge. Pervasive overprint by sinistral shear within the CRS marginal slice and northern Tannheim thrust sheet suggests sinistral W-E striking transform faults cutting across this foreland, decoupling CRS marginal slice and FSZ from the main body of the NCA and enabling an independent evolution of the CRS marginal slice from the Early Cretaceous onwards. Subsequent Late Cretaceous and younger shortening leads to successive incorporation of Arosa zone, Rhenodanubian Flysch (RDF) and Helvetic units into the Alpine nappe stack; the Tannheim thrust representing the basal thrust of the NCA. Growth strata within thrust-sheet-top deposits (Branderfleck-Fm.) give evidence for refolding of thrust sheet boundaries. In a typical thin-skinned fold-and-thrust belt, deformation should cease towards the thrust front, whereas within the NCA it increases. An Austroalpine thrust front controlled by E-trending transform faults could cause an increase in deformation towards the most external NCA and explain the absence of the Arosa zone between Allgäu and Vienna. Such faults would most probably also cut out Lower Austroalpine units. Therefore, RDF and CRS marginal slice are juxtaposed; the latter found in the tectonic position of the Arosa zone. The presence of transform faults underlines the strong imprint of the opening of the North Atlantic Ocean on the depositional setting and tectonic evolution of the NCA.
Metamorphic tourmaline and its petrogenetic significance from the Maramureș Mountains (East Carpathians, Romania)
Authors: Mosonyi Emilia , Forray Ferenc L.
Published: May 2023

This study describes mineralogical and crystallochemical characteristics of metamorphic tourmalines from an Alpine shear zone in a Variscan metamorphic rock sequence from the Maramures region in the northern part of the East Carpathians. We use this mineral to unravel aspects of the evolution of the tourmaline bearing host rocks and compare the crystallo-chemical characteristics to other tourmalines from Alps. Petrographic and microstructural observations, as well as electron microprobe analyses on several zoned tourmalines and associated minerals (mica, feldspar) from mylonitic schist of the Rebra terrane (Maramureș Mountains), indicate that the pre-kinematic tourmalines belong to the alkali group (Na dominant), hydroxyl dominated on the crystallographic W-site and can be assigned to the species dravite and schorl. The tourmaline-bearing rocks have a metasedimentary protolith. The analysed porphyroblasts, rotated by simple shear, show corroded rim that are interpreted to have formed due to pressure release. Three main compositional zones were evidenced on a tourmaline porphyroblast: a core zone and two asymmetrically arranged inclusion-poor/free rims, all formed in pre-alpine prograde metamorphic conditions. Based on mineral microstructural relations and geothermobarometry (tourmaline–muscovite, tourmaline–plagioclase geothermometry and phengite geobarometry), the metamorphic peak conditions of the investigated Rebra terrane were evaluated to have been at a temperature of ca. 590 to 620 ± 22 °C and Pmin = 5.5 - 6.0 ± 0.5 kbar. By observing dynamically recrystallized microstructures in quartz and feldspar in the shear zone a temperature of 350 - 400 °C was estimated and the quartz paleopiezometry outlined a differential stress of about 1.5 kbar that implied only minor chemical change in tourmaline outer zone.
La estructura del Paleozoico en la transición entre el Domo del Garona y el Sinclinorio del Valle de Arán y su relación con el metamorfismo (Zona Axial pirenaica)
Authors: García-Sansegundo Joaquín , González Santano Beatriz
Published: May 2023

En la transición entre el Domo del Garona y el Sinclinorio del Valle de Arán en la Zona Axial pirenaica dominan las estructuras variscas, cuyo orden cronológico y relación con el metamorfismo se pretende establecer en este estudio. Los dos primeros episodios de deformación varisca (D1 y D2) originan pliegues, foliaciones tectónicas y cabalgamientos en un contexto compresivo. Entre ambos eventos se produce un primer pulso magmático, con la intrusión de sills paralelos a la foliación regional (S1). El episodio de deformación D3, se desarrolla en condiciones extensionales durante el colapso del Orógeno Varisco y contemporáneamente con el clímax metamórfico y la intrusión del Granitoide de Bossòst.
Estructura y metamorfismo del Paleozoico del sector suroccidental del Macizo de Lys-Caillaouas (Zona Axial pirenaica, Huesca, España)
Authors: Pérez-Cáceres Irene
Published: May 2023

En la zona de estudio afloran rocas de edad comprendida entre el Cambro-Ordovícico y el Devónico. El objetivo de este trabajo es establecer la secuencia de deformación para comprender su significado tectónico y su relación con el metamorfismo. En el Macizo de Lys-Caillaouas, después del desarrollo de las principales estructuras variscas (D1), se produce un metamorfismo de grado medio, con el crecimiento de porfiroblastos que, posteriormente, sufren deformación por cizalla relacionada con la intrusión del Granitoide de Lys-Caillaouas. Al Sur, la Falla Eriste-Valarties separa este Macizo de una zona dominada por pliegues D2 que deforman las estructuras D1. Esta falla parece responsable de la distribución espacial de las estructuras variscas y presenta un rejuego alpino.
About mother Yulia Savinovskikh, deprived of adopted children because of desire to change sex (tragic legal consequences of imperfections of psychiatric classifications)
Authors: Mendelevich Vladimir D.
Published: May 2023

In the article the case of Yulia Savinovskikh from whose family two adoptive juvenile children who have lived within several years with trustees and their own children and received during this time the effective help in therapy of the chronic diseases have been withdrawn, is analyzed. The surgery fact (a bilateral mastectomy) for the purpose of the further sex change which was carried out in Yu. Savinovskikh after approval of her husband and relatives, has formed the basis for withdrawal of children. Justification of the judgment was the instruction on the fact that the transsexualizm belongs to the category of mental disorders in the presence of which the person cant adopt the child or accept him under guardianship. The described case has highlighted aspect, relevant for modern psychiatry, the actual legal equating of behavioural disorders and deviations, to mental with distribution of rights deprivation of such persons.
Spontaneus resolution of syringomyelia is a rare variant of the disease course: analysis of clinical and neuroimaging descriptions
Authors: Mendelevich Elena G. , Nurullina Chulpan S.
Published: May 2023

The cases of syringomyelia described in the literature with spontaneous collapse of the cavity are analyzed. Differences among patients with cavity decay in childhood and adults are assessed. The basic theories of cavity shedding in syringomyelia are presented in this article.
Lithium in drinking water: is it really a real reducing in mortality?
Authors: Sivolap Yuri P. , Portnova Anna A.
Published: May 2023

Studies of the hypothetical association between lithium in drinking water and suicide rates are considered. It is noted that some studies provide evidence of a negative association between the concentration of lithium in water and the risk of suicide, while other studies do not find convincing evidence of such association. Obviously, this issue requires further epidemiological studies that would take into account the impact of additional, primarily socioeconomic, factors.

The authors of the article express the opinion that, regardless of the ability of lithium in drinking water to reduce the mortality of the population, lithium preparations, due to their obvious and proven anti-suicidal properties in pharmacological application, should be used more often in clinical practice.
Transurethral incision of the bladder neck in recurrent bladder neck stenosis
Authors: Popov Sergey V. , Orlov Igor N. , Tsoy Aleksey V. , Topuzov Timur M. , Malik Valeriya V. , Neymark Alexander I. , Neymark Boris A.
Published: May 2023

BACKGROUND: Transurethral incision of the bladder neck is one of the main methods of correction of bladder neck stenosis that occurred after treatment of patients with benign prostatic hyperplasia. This technique involves endoscopic dissection in the area of the stenosed area without removing scar tissue. Taking into account the emergence of new reconstructive methods of surgical intervention in patients with recurrent bladder neck stenosis the expediency of using transurethral incision of the bladder neck in recurrent cases remains a subject of discussion.
AIM: The aim of the study is to evaluate the effectiveness of the use of transurethral incision of the bladder neck in patients with recurrent bladder neck stenosis.
MATERIALS AND METHODS: The study included 30 patients with a diagnosis of recurrent bladder neck stenosis who were treated in the period from 2012 to 2022. in Clinical Hospital of St. Luke and was performed transurethral incision of the bladder neck using bipolar electrosurgical energy. The diagnosis of bladder neck stenosis was established on the basis of complaints, anamnesis, uroflowmetry with determination of the volume of residual urine, ureteroscopy, retrograde urethrography. Recurrence was recorded when the maximum urination rate below 12 ml/s, there was an episode of acute urinary retention, or the need for additional surgical intervention for bladder outlet obstruction.
RESULTS: All 30 patients underwent transurethral incision of the bladder neck using bipolar electrosurgical energy. The average duration of surgery was 22.9 minutes. The degree of postoperative complications did not exceed grade II according to the Clavien scale. The frequency of de novo stress urinary incontinence was detected only in one patient, which resolved spontaneously within 6 weeks. The maximum urination rate after 3 months was 14.73 3.61 ml/s, while after 6 months there was a significant decrease to 10.91 6.92 ml/s, and after 12 months to 9.4 7, 65 ml/s. The absence of recurrence in patients after TUI BN during the observation period was noted in 17 (56.67%) patients.
CONCLUSIONS: Transurethral incision of the bladder neck using a bipolar electrode is a safe method for correcting bladder neck stenosis, but in recurrent cases it has limited efficacy. In this regard, in patients with a large number of endoscopic interventions in history, other methods of bladder neck reconstruction should be chosen.
History of urine diversion techniques
Authors: Martov Alexey G. , Korobov Alexey A. , Kyzlasov Pavel S. , Sergeyev Vladimir P. , Kuzmin Igor V. , Kochetov Alexander G. , Kolpatsinidi Fedor G. , Sokolov Sergey A. , Mustafayev Ali T.
Published: May 2023

The review article is devoted to the history of the development of urine diversion methods, starting from the very first operations for the imposition of skin fistulas and ending with modern high-tech surgical interventions. The advantages and disadvantages of various methods of urine diversion are described. It is shown that the gold standard today is orthotopic bladder plastic surgery, which allows to achieve good functional results and a high quality of life for patients.
Annual trends in semen parameters among men attending a fertility center between 2016 and 2022
Authors: Korneyev Igor A.
Published: May 2023

BACKGROUND: Multiple studies have shown sperm concentration and count decline in many countries, however, authors conclusions were inconsistent. These types of studies were not conducted in Russia so far.
AIM: To evaluate and analyze semen parameters among men attending a fertility center in St. Petersburg between 2016 and 2022.
MATERIALS AND METHODS: In a retrospective study parameters of 14234 consequent semen analyses performed according to WHO guidelines (2010) were sorted, analyzed and compared by year.
RESULTS: The distribution parameters of the ejaculate volume did not have change over observation period. Azoospermia and cryptozoospermia were detected in 597 (4.2%) and 435 (3.1%) men respectively. A downward trends for sperm concentration of 1.6 million/ml (1.9%)/year and sperm count of 7 million (1.8%)/year were found, with simultaneous annual increase of 1.3% in the proportion of progressively motile spermatozoa. No noticeable changes in the number of motile spermatozoa and the proportion of spermatozoa with normal morphology were found.
CONCLUSIONS: Further research is needed to obtain final conclusions about the gradual decline in the semen quality and reproductive function of men, also in other centers of the Russian Federation.
Analisis jaringan komunikasi dalam kelompok Paguyuban Wirausaha Wanita Berdaya Kalirejo Lawang
Authors: Hariani Aisyiyah , Prakris Maria Apolonia , Ananda Kun Sila
Published: May 2023

The Empowered Women Entrepreneurs Association is a group consisting of women entrepreneurs in the Kalirejo Village area which is one of the groups that brings together women entrepreneurs. The purpose of the formation of this association group is to share information related to the business world. Meanwhile, the purpose of this research is to discuss how the communication network is formed in the group and then find out the most influential actors and the communication network formed in the Empowered Women Entrepreneurs Association. The research method used is quantitative then to analysis the data using the network analysis method. The results of this study explain that the communication network formed is a channel communication network. Then the communication that was formed at the Empowered Women Entrepreneur Association was motivated by the presence of the most influential actors and also generated seventy-six clicks with a high density.

Paguyuban Wirausaha Wanita berdaya merupakan kelompok yang terdiri dari para wirausaha wanita yang berada di daerah Kelurahan Kalirejo yang merupakan salah satu kelompok yang menghimpun para wirausahawan wanita tujuan dari dibentuknya kelompok paguyuban ini adalah untuk saling berbagai informasi berkaitan dengan dunia usaha. Sedangkan tujuan dalam penelitian ini adalah akan membahas tentang bagaimana jaringan komunikasi yang terbentuk dalam kelompok kemudian mengetahui aktor yang paling berpengaruh dan jaringan komunikasi yang terbentuk dalam Paguyuban Wirausaha Wanita Berdaya. Metode penelitian yang digunakan adalah kuantitatif kemudian untuk menganalisis data menggunakan metode analisis jaringan. Hasil dari penelitian ini menjelaskan bahwa jaringan komunikasi yang terbentuk adalah jaringan komunikasi saluran. Kemudian komunikasi yang terbentu pada Paguyuban Wirausaha Wanita Berdaya dilatarbelakangi dari adanya aktor yang paling berpengaruh dan juga menghasilkan tujuh puluh enam klik dengan kepadatan yang tinggi.
PERKEMBANGAN TATA KOTA SURABAYA PADA TAHUN 1870-1940
Authors: Andana Muhammad Lingga , Afhimma Izza Yuspriana , Ashiva Silvia Nurul
Published: May 2023

The city of Surabaya became one of the areas that attracted the interest of Europeans to perpetuate power and establish government as well as establish economic relations, especially trade with indigenous peoples. The city of Surabaya has been given the authority to regulate its territory, thus giving rise to the term Gemeente. This article aims to explain how Surabaya’s urban planning has changed across centuries, from 1870-1940. The method used in this article is the study of literature and historical methods. The development of the Surabaya City layout was motivated by the passing of the agrarian and the sugar law. As a result, many people from various ethnic migrated to Surabaya and formed settlements. In addition, another impact is the renewal of Surabaya City infrastructures such as railroads, markets, and highwaysKota Surabaya menjadi salah satu wilayah yang menarik minat orang Eropa untuk melanggengkan kekuasaan dan mendirikan pemerintahan serta menjalin hubungan ekonomi khususnya perdagangan dengan masyarakat pribumi. Kota Surabaya telah diberi kewenangan untuk mengatur wilayahnya sendiri hingga memunculkan istilah Gemeente. Artikel ini bertujuan dalam menjelaskan bagaimana tata Kota Surabaya berubah secara lintas abad, yaitu dari tahun 1870-1940. Metode yang digunakan dalam artikel ini adalah studi kepustakaan serta metode sejarah. Perkembangan tata Kota Surabaya dilatarbelakangi oleh disahkannya undang-undang agraria serta undang-undang gula. Dampaknya banyak penduduk dari berbagai etnis yang bermigrasi ke Kota Surabaya serta membentuk pemukiman-pemukiman. Selain itu dampak lain adalah adanya pembaruan infrastruktur Kota Surabaya seperti rel kereta api, pasar, dan Jalan raya.