bluuebunny/crossref_metadata_2025 huggingface dataset:
The Association between EGFR Expressions with Histopathological Grade and Perineural Invasion in Prostatic Adenocarcinoma
Authors: Ria Oktavia  , R. Zuryati Nizar  , Yenita  , Tofrizal
Published: May 2022

ABSTRAKLatar belakangEpidermal Growth Factor Receptor (EGFR) berperan penting pada karsinogenesis beberapa karsinoma termasuk karsinoma prostat.Overekspresi EGFR pada adenokarsinoma menyebabkan sel tumor menjadi resisten terhadap terapi hormonal. Tujuan penelitian iniuntuk mengetahui hubungan antara ekspresi EGFR dengan derajat histopatologik dan invasi perineural pada adenokarsinomaprostat.MetodePenelitian ini merupakan penelitian observasional dengan desain cross sectional dengan sampel penelitian sebanyak 60 kasusadenokarsinoma prostat yang telah didiagnosis di 5 Laboratorium Patologi Anatomik di Sumatera Barat periode Januari 2015 sampaiDesember 2017. Sampel diperoleh dari blok parafin yang berasal dari jaringan hasil operasi transuretral resection of prostat (TURP)dan prostatektomi kemudian dilakukan reevaluasi terhadap derajat histopatologik dan invasi perineural. Ekspresi EGFR pada seltumor dilihat dengan pewarnaan imunohistokimia. Analisis statistik menggunakan uji Chi-Square.HasilEkspresi EGFR positif ditemukan pada 38 kasus (63,33%) dan kasus terbanyak dengan EGFR positif adalah poorly differentiated(57,9%). Kasus adenokarsinoma prostat dengan invasi perineural paling banyak ditemukan dengan ekspresi EGFR positif (42,1%).Analisis statistik menunjukkan terdapat hubungan bermakna antara ekspresi EGFR dengan derajat histopatologik (p=0,003) dan tidakterdapat hubungan yang bermakna antara ekspresi EGFR dengan invasi perineural (p=0,129).KesimpulanTerdapat hubungan yang bermakna antara ekspresi EGFR dengan derajat histopatologik pada adenokarsinoma prostat dan tidakterdapat hubungan antara ekspresi EGFR dengan invasi perineural.
Correlation between CD133 and EGFR Expression with Grading of Ovarian Carcinoma
Authors: Agung Dwi Suprayitno  , Dyah Fauziah  , Gondo Mastutik
Published: May 2022

BackgroundOvarian carcinoma account for 90% of all malignant ovarian tumors. Epidermal Growth Factor Receptor (EGFR), also known asErbB1/HER1, has an important role in tumor cell proliferation. CD133 is a marker for hematopoietic stem cell and it is involved in tumorcell proliferation, self renewal and cell differentiation. The objective to analyze the expression of CD 133 and EGFR in high grade andlow grade ovarian carcinoma, and to determine the correlation between the expression of CD133 and EGFR expression in ovariancarcinoma.MethodsThe study was conducted with observational and cross sectional method on paraffin blocks of patients diagnosed as ovariancarcinoma from 1 January until 31 December 2017 in Dr. Soetomo Hospital. Ovarian carcinoma was divided into 2 grade, low gradeand high grade. Immunohistochemistry for EGFR and CD133 was performed. Immuno-reactive Score (IRS) was applied to evaluatethe expression of EGFR and CD133. The difference expression of CD133 and EGFR in low grade and high grade ovarian carcinomawas analyzed with Mann-Whitney test. Correlation between CD133 with EGFR was analyzed with Spearman test.ResultsThere were significant difference in expression of CD133 (p=0.0001) and EGFR (p=0.0005) in high grade and low grade OvarianCarcinoma. There was significant positive correlation between CD133 and EGFR expression in Ovarian Carcinoma (p=0.035; r=0.37)ConclusionExpression of CD133 and EGFR were higher in high grade ovarian carcinoma. The higher expression of CD133 will increaseexpression of EGFR in ovarian carcinoma. Both markers may be used as prognostic factor.
The Role of Memory T Cells in Controlling the Covid-19 Pandemic
Authors: Kusmardi  , Ramadhian N Dimas , Pratomo Irandi P , Tedjo Aryo
Published: May 2022

ABSTRACTEvaluation of changes in antibody orders is a common exclusion in vaccination strategies because of the method ofanalysis. The fact that protection by antibodies produced by the Severe Acute Respiratory Syndrome Coronavirus-2(Sars-Cov-2) infection both naturally and through vaccines will decrease in less than one year, is a challenge for acountry with a large population like Indonesia to run its vaccination program. The main challenge is whether thevaccination strategy adopted will overcome the vaccine barrier and the race between the rate of vaccination and therate of viral mutation and antibody reduction. In addition to antibodies, the adaptive immune system is also run by Tcells that are included in the cell-mediated immune system (CMI) group. In patients with asymptomatic or mildsymptoms of Coronavirus 2019 (Covid-19), T and CMI responses are known to appear in some patients who are notknown to have been exposed to Sars-Cov-2 before. This evidence suggests that the adaptive catastrophe for SarsCov-2 has been acquired by ordering memory T cells and may last longer than previously thought. For countries withlarge populations, this will certainly help overcome the limitations of vaccines and the time needed to implement theirvaccination strategies.
Characteristics of Cervical Precancerous Lesions at Tertiary Hospital in West Java, Indonesia
Authors: Maulana Akbar , Dewayani Birgitta Maria , Hernowo Bethy Surjawathy
Published: May 2022

BackgroundThe incidence of cervical cancer was continues to increase even though various risk factors and prevention efforts have been made.Cervical cancer begins with the development of a precancerous lesion (Cervical Intraepithelial Neoplasia/CIN) which is an abnormalcell growth in the cervical epithelium. This study aims to see the proportion of risk factors for cervical cancer in CIN patients at Dr.Hasan Sadikin, Bandung.MethodsThis study used a cross-sectional retrospective descriptive research method using secondary data of CIN patients for the periodJanuary 2016 - December 2020 from the archives of the anatomical pathology laboratory and clinical medical records of patients inthe form of age, marriage history, total parity, age at marriage, age at menarche, usage of hormonal contraceptives, smoking habits,clinical symptoms and histopathological degrees.ResultThere were total sample 40 cases of CIN. The 41-50 year age category is the largest age range of all NIS cases (35%). The resultsof this research data were history of marriage 1x (85%), age at marriage in the range of 20-30 years (47.5%), history of menarche inthe age range 10-15 years (90%), history of multiparous (65%), used of hormonal contraceptives (52.5%), non-smoking habits(67.5%), clinical symptoms of vaginal bleeding (42.5%) and histopathological grade of CIN 1 (47.5%).ConclusionCervical precancerous lesions at RSUP Dr. Hasan Sadikin occurred between fourth and fifth decades of life with a history of beingmarried once, multiparous, married at the age of 20-30 years, menarche at the age of 10-15 years, using hormonal contraception,not smoking, complaints of vaginal bleeding and the majority of cases were CIN 1.
Productivity and Preferences of New Potato Varieties and their Relationships in Five Districts of Bhutan
Authors: Rai Pradeep , Bajgai Yadunath , Lhadon Tshering , Lobzang  , Sangay
Published: May 2022

Potato (Solanum tuberosum L.) is one of the widely cultivated horticultural commodities in Bhutan. Over the years yields of potato at national level have stagnated due to degeneration of seeds and lack of appropriate varieties in the country. To address the yield stagnation issue, two potato varieties (Yusi Maap and Nasphel Kewa Kaap (NKK)) were introduced in recent years. To understand crop productivity and farmer’s preferences of the new varieties this study was conducted in Bumthang, Chukha, Gasa, Haa, and Wangduephodrang districts from 2017 to 2018 using the field demonstration trials and participatory varietal selection method. Desiree, the popular variety was used as a control. On an average across years and dzongkhags, mean yields of the NKK and Yusi Maap were 10.4 and 10.5 tons/acre, respectively. Hence, yields of Yusi Maap and NKK were approximately 30% higher in comparison to Desire, which was 7.30 tons/acre on an average across the years and dzongkhags. Being one of the oldest varieties, Desiree consistently showed lower productivity compared to other two varieties due to seed degeneration and quality deterioration. Although the productivity difference between NKK and Yusi Maap is minimal (0.10 tons/acre) the preference votes of Yusi Maap was 1.3 times that of NKK indicating the higher level of preferences for Yusi Maap. There was positive significant relationship (P=0.02) between the potato productivity and the farmer’s preference suggesting that higher productivity attracted more votes and lower productivity attracted lesser votes. Further higher productivity is also seen as a means to earn cash income for the household to achieve food security in terms of household’s consumptions through the sale of potatoes. The findings provide a sound scientific basis to guide program implementers and policy-makers in terms of potato research and development at the national level.
Comparative Study on Physio-chemical and Organoleptic Attributes of Apple Wine Fermented from Local and Imported Yeasts
Authors: Lhamo Sonam , Dorji Karma
Published: May 2022

With home micro-brewing on the rise, use of local indigenous yeast in the fermentation process is a prevalent practice in the country. The indigenous strain found in locally processed yeast can impart certain desirable flavours and aromas to the fermented wine. Furthermore, the use of antioxidant-rich wild herbs in local yeasts is reported to enhance the nutritional value of the wine. However, local yeasts are home-made under dubious processing conditions and cannot afford the advantage of being in a pure uncontaminated microbial form, unlike the commercial strains. This might affect the fermentative capability and compromise the end quality of the wine. Thus, this study was conducted to compare the organoleptic acceptability and physio-chemical properties (total soluble solid, alcohol by volume, transmittance value, pH and titratable acidity) of apple wine fermented by two local yeasts from Trashi Yangtse and Samtse districts in Bhutan and one commercial yeast manufactured in India. Both the local yeast strains seem to yield a wine with better appearance (clarity) and taste (sweetness) based on the sensory evaluation result. In terms of fermentative capability, the commercial strain had shorter fermentation time, but the local strains were able to yield wine with similar alcohol strength to the commercial strain. For the physio-chemical parameters, only pH and titratable acidity results were significantly different with the wine from local yeast from Samtse having a significantly higher malic acid content, while the wine from commercial yeast had lower pH. However, the results deduced from the sensory evaluation does not compliment the values obtained for Total Soluble Solute and clarity measurement. Besides, the difference in pH did not resonate with the taste perception (i.e., lowest pH wine considered sweeter). Thus, other flavour components might have a role to play in the sweet taste perception. Overall, the local strains showed promising results in terms of fermentation capability (ability to convert sugar to alcohol) and organoleptic attributes of the end wine in comparison to the commercial strain.
Assessment of Nursery Methods and Manures for Cultivation of Chirayita (Swertia chirayita Buch-Ham.) in Lauri Gewog, Bhutan
Authors: Rabgyal Jimba , Bajgai Yadunath , Pelden Karma , Tobgay Tshering , Rinchen Sonam
Published: May 2022

Chirayita (Swertia chirayita) is a medicinal plant and is native to the temperate Himalayas. It is widely used in traditional and modern medicines with an increased global demand, leading to unsustainable harvesting, causing the decline, and critically endangering the species. Hence, we hypothesized that chirayita could be domesticated and tested this hypothesis at Lauri Gewog in southeastern Bhutan. Four nursery methods and four organic manure treatments were tested using Completely Randomized Design with three replicates. The average seedling density across the four treatments at mid altitude was 2356 seedlings/m2, and that of high altitude was 1202 seedlings/m2. The seedling density at mid altitude was 96% higher compared to that of high altitude; however, there were significant differences between the treatments only in high altitude (P = 0.003) and not in mid altitude. The methods were non-significant at mid altitude, mainly due to the large variability of data. Interestingly, the manure treatments were not significant compared to the control implying that the chirayita could be non-responsive to the application of manures in the study conditions. Fresh weight of chirayita in the control plot was 14, 19 and 29% higher than ‘compost’, ‘FYM’ and ‘compost+FYM (1:1)’ treatment plots. Further, this research provides an alternative low-cost nursery technique for adoption by chirayita farmers while also providing information for policymakers and environmental conservationists in developing strategies for conservation of a critically endangered species like chirayita.
Otimização de scheduling de tarefas para satélite de observação da Terra
Authors: Melo Junior Jose Carlos de , Belderrain Mischel Carmen Neyra , De Marchi Mônica Maria , Geraldo Diego
Published: May 2022

Satélites de Observação da Terra são satélites que possuem a capacidade de imagear alvos na superfície. Entretanto, o que se observa na prática é que a demanda de requisições de imageamento normalmente excede a capacidade desse tipo de Sistema Espacial. Assim, a otimização do scheduling de tarefas de imageamento é de vital importância, pois permite que esses Sistemas possam ser operados eficientemente. Neste trabalho, o problema é modelado implementado na plataforma AEROGRAF, e um Algoritmo Genético híbrido é proposto para resolver o problema. O método proposto permitiu otimizar um scheduling para até 300 alvos em poucos segundos, maximizando a função objetivo proposta no artigo.
Masalah Pelayanan Kesehatan pada Jemaah Umrah
Authors: Vestabilvy Evi , Prihatini Fitria
Published: May 2022

Masalah pelayanan kesehatan umrah belum memiliki legal aspek, sehingga problem yang terjadi di lapangan tidak dapat diatasi secara sistemik. Dengan ditetapkanya kuota jemaah haji maka berakibat membludaknya jemaah yang akan melakukan umrah. Banyak berita yang mengabarkan saat jemaah melakukan umrah dilanjutkan dengan wisata baik religi maupun bukan, jemaah yang jatuh sakit akan ditinggal oleh travel baik di rumah sakit negara transit, Arab Saudi maupun di negara tujuan wisata mereka.  Akibatnya kementerian luar negeri yang akan menanggung akibatnya dengan membayar biaya rawat inap, dan mengurus jenasahnya jika meninggal. Tujuan penelitian ini secara umum untuk menganalisis masalah kesehatan yang ditimbulkan selama umrah di luar negeri.  Kajian ini menggunakan desain cross sectional, metode kualitatif dan kuantitatif dengan pendekatan deskriptif eksploratif.  Populasi adalah stakeholder lembaga penyelenggara haji dan umrah, organisasi profesi haji, LSM dan jemaah umrah. Sampel dalam penelitian ini adalah penentu kebijakan (lintas sektor dan lintas program); penyelenggara haji/umrah (Kesthuri), organisasi haji (AKHI, organisasi profesi) dan kelompok masyarakat. Penyelenggaraan pelayanan kesehatan jemaah umrah belum dilakukan secara maksimal sebab belum ada kebijakan khusus yang menjadi payung hukum. Jumlah jemaah umrah sampai bulan Juni tahun 2015 berdasarkan data penerbangan sebanyak 471.250 orang. Tidak terlaporkan data  jemaah yang sakit maupun meninggal selama penerbangan. Jumlah  jemaah umrah berdasarkan penggunaan vaksin meningitis tahun 2015 sampai dengan bulan Juni 2015 sebanyak 329.141 orang.  Jemaah umrah yang sakit di luar negeri yang dilaporkan Kemenag pada tahun 2014 dan Februari 2015 sebanyak 11 orang berasal dari Negara Bangkok dan Dubai dan yang meninggal sebanyak 4 orang.
Reseña: L’urbanisme face aux villes anciennes
Authors:   Instituto Politécnico Nacional, Urrieta García Salvador Esteban
Published: May 2022

La obra de Gustavo se constituye como un clásico de la literatura en materia de patrimonio urbano, primero por inventar este término, y segundo por el sentido ampliamente visionario que le da a la conservación urbano-arquitectónica. Esta versión francesa le agrega un plus a la obra, a través de la introducción que hace Françoise Choay, al reiterar por un lado la importancia que la figura de Giovannoni sigue teniendo en el ámbito de la conservación patrimonial (que ella ha difundido ampliamente), y por otro lado al señalar y explicar las balizas conceptuales que hacen más digeribles los temas y conceptos fundamentales de este libro, que van desde las características de las ciudades antiguas y modernas, a la planificación urbana, pasando por el ordenamiento y puesta en valor de los núcleos internos. Todo esto, dentro del marco de la vida cotidiana. Desde este punto de vista no resulta extraño que los postulados de Giovannoni hayan sido retomados por los practicantes de la preservación de las ciudades históricas a lo largo del siglo XX, al aplicar la “conservación integrada”, particularmente en Europa.
Relevansi Teori Keagenan Terhadap Aktifitas Off Balance Sheet Pada Bank-Bank Komersil Di Indonesia
Authors: Kambuaya Quincy Fransiska
Published: May 2022

Off-Balance-Sheet adalah aset dan kewajiban yang mempengaruhi masa depan, dalam bentuk neraca kontijensi dari sebuah institusi keuangan. Sehingga mereka memiliki dampak langsung pada profitabilitas masa depan dan kinerja dari lembaga perbankan. Hal ini mengakibatkan manajemen efisien terhadap item-item Off-Balance Sheet (OBS) sebagai pusat pengendalian risiko eksposur secara keseluruhan dalam institusi keuangan modern yang juga lembaga perbankan merupakan bagian di dalamnya. (Saunder & Corneet: 376).Kata Kunci : Off-Balance-Sheet, Manajemen Keuangan
Analisis Persepsi Masyarakat Terhadap Pengelolaan Dana Bantuan Keuangan Pada Masyarakat Kampung Napua Distrik Napua Kabupaten Jayawijaya
Authors: Sumbung Delvie , Umar Hasan Basri , Patinggi P. N. , Klara Antonia
Published: May 2022

Penelitian ini bertujuan untuk menganalisis Persepsi Masyarakat Terhadap Pengelolaan Dana Bantuan Keuangan Pada Masyarakat Kampung Napua. Untuk mengungkap permasalahan, diadakan penelitian dengan jumlah sampel sebanyak 50 orang masyarakat yang dianggap mengetahui tentang pengelolaan dana bantuan keuangan dan penelitian dokumentasi bertempat di Kampung Napua.   Teknik pengumpulan data yang digunakan adalah berupa angket (kuesioner), melakukan wawancara dan pengolahan data dari laporan-laporan yang diperoleh. Hasil penelitian menunjukkan bahwa perencanaan dan alokasi pengelolaan dana bantuan keuangan pada masyarakat Kampung Napua pada tahun 2016  cukup tinggi dan sangat berpengaruh dalam menunjang kesejahteraan masyarakat. Nilai rata-rata jawaban responden atas variabel dana bantuan pendidikan adalah sebesar 88,32%. Jumlah responden dengan nilai rata-rata tertinggi adalah pernyataan “Dengan adanya bantuan dana pendidikan dapat mengurangi beban masyarakat untuk memenuhi kebutuhan anaknya” yaitu sebesar 92,00%. Nilai rata-rata jawaban pernyataan variabel bantuan dana kesehatan sebesar 80,80% yaitu pada pertanyaan Dengan adanya bantuan dana kesehatan dapat mengurangi beban masyarakat untuk memenuhi kebutuhan hidup sehat dengan perolehan nilai presentase sebesar 96,00%. Pada bantuan infrastruktur jumlah berkaitan dengan masyarakat yang sangat merasakan adanya manfaat dari bantuan dana infrastruktur dalam menunjang pembangunan kampong adalah 81,84%. Sehingga pengelolaan dan bantuan keuangan dapat optimal dan berhasil dengan baik, terutama dalam bidang pendidikan,kesehatan, infraktruktur pada masyarakat kampung Napua Distrik Napua Kabupaten Jayawijaya.Kata Kunci : Dana Bantuan Pendidikan, Kesehatan, Infrastuktur
Analisis Dampak Program Cetak Sawah Terhadap Tingkat Pendapatan Petani Padi Di Distrik Tanah Miring Kabupaten Merauke
Authors: Riandjumahge Herbekti , Riani Ida Ayu Purba , De Queloe Flora Yvonne , Kaiwai Hans Z.
Published: May 2022

Untuk meningkatkan produksi padi dalam rangka memenuhi ketersediaan beras maka produksi harus ditingkatkan, salah satunya dengan penambahan perluasan areal tanam. Dengan adanya program cetak sawah baru di Kabupaten Merauke, diharapkan program yang telah dan yang akan dijalankan apakah dapat mengurangi permasalahan yang terdapat di tingkat petani sehingga dapat memberikan kontribusi yang menyata bagi petani padi yaitu meningkatkan pendapatan petani padi.Sasaran kegiatan Perluasan Sawah diarahkan pada lahan-lahan pertanian yang potensi untuk dikembangkan menjadi lahan petanian produktif dan dapat dimanfaatkan untuk pengembangan lahan pertanian. Dengan adanya perluasan sawah ini diharapkan masyarakat dapat menyediakan beras untuk peningkatan ketahanan pangan di wilayahnya dan mampu meningkatkan produksi padi di Kabupaten Merauke. Tujuan penelitian ini untuk mengetahui besarnya perbedaan tingkat produktivitas lahan dan pendapatan petani sebelum menerima dan sesudah menerima Bantuan Program Cetak Sawah di Kampung Ngguti Bob Distrik Tanah Miring Kabupaten Merauke. Hasil penelitian ini membuktikan rata-rata produktivitas lahan yang dihasilkan sebelum menerima bantuan program cetak sawah sebesar 4,00 ton/ha, sedangkan sesudah menerima bantuan cetak sawah sebesar 4.24 ton/ha. Pendapatan terbanyak pada petani sebelum menerima program cetak sawah pada kisaran pendapatan Rp. 15.500.000 s/d 18.000.000. Pendapatan  tertinggi petani sesudah menerima program cetak sawah pada kisaran Rp. 27.500.000 s/d Rp. 30.000.000.Kata kunci  :  Cetak Sawah, Pendapatan Petani
Analisis Potensi Pendapatan Asli Daerah Melalui Optimalisasi Pemungutan Bea Perolehan Hak Atas Tanah Dan Bangunan Di Kota Jayapura
Authors: Ansanay Freddy , Wakarmamu Thobby , Urip Transna Putra
Published: May 2022

BPHTB Waris adalah pengenaan pajak kepada ahli waris, sehubungan dengan peralihan hak atas tanah dan bangunan dari pewaris kepada ahli warisnya. Dalam contoh 1 pada penjelasan atas pasal 4 ayat (2) Peraturan Pemerintah Republik Indonesia Nomor 111 Tahun 2000 tentang Pengenaan BPHTB Karena Waris dan Hibah Wasiat, terdapat ketentuan bahwa apabila NPOP lebih rendah dari NPOPTKP maka NPOPKP menjadi Nihil dan BPHTB Terutang juga menjadi Nihil.  Penelitian ini menggunakan metode Analisis Deskriptif dengan Jenis Data Kuantitatif dari Sumber Data Sekunder, yakni berupa Laporan Target dan Realisasi Pendapatan Daerah Kota Jayapura Tahun 2012 – 2016, Data BPHTB Waris di Kota Jayapura Tahun 2012 – 2016, Data Klasifikasi NJOP Bumi Untuk Objek Pajak Sektor Perdesaan dan Sektor Perkotaan serta buku-buku, peraturan perundang-undangan, serta dokumen-dokumen resmi dari pemerintah terkait BPHTB.  Kesimpulan penelitian adalah: (1) Jumlah wajib pajak yang melakukan pendaftaran hak BPHTB karena waris dalam kurun waktu 2012-2016 mempunyai kecenderungan naik dengan trend positif dan rata-rata yang dicapai adalah sebesar 20 persen. (2) Jumlah Luas tanah yang ditransaksikan pada BPHTB waris mempunyai kecenderungan naik dengan trend positif dan rata-rata yang dicapai adalah sebesar 20 persen. (3) Jumlah Nilai Perolehan Objek Pajak (NPOP) sebagai dasar pengenaan BPHTB Waris mempunyai kecenderungan menurun dengan trend negatif dan rata-rata yang dicapai adalah sebesar 20 persen. (4) Jumlah BPHTB Terutang pada BPHTB waris mempunyai kecenderungan naik dengan trend positif dan rata-rata yang dicapai adalah sebesar 20 persen. (5) Upaya Optimalisasi Pemungutan BPHTB pada Peralihan Hak atas Tanah karena Waris di Kota Jayapura diantaranya dengan melakukan Revitalisasi terkait Nilai Perolehan Objek Pajak (NPOP) dan Nilai Jual Objek Pajak (Rp/m2) dan juga Relevansi Klasifikasi Klas Bumi dan Zona Nilai Tanah (ZNT) sehingga Potensi Pendapatan Asli Daerah dapat dikembangkan melalui Optimalisasi Pemungutan Bea Perolehan Hak atas Tanah dan Bangunan.Kata Kunci : Potensi PAD, Optimalisasi Pemungutan BPHTB, BPHTB Waris, NPOP
Implementasi Kredit Usaha Rakyat (KUR) Guna Meningkatkan Pendapatan Nasabah Usaha Mikro Kecil Dan Menengah Di Kota Jayapura (Studi Kasus Bank Papua Jayapura)
Authors: Hernaningsih Tri Listyo , Riani Ida Ayu Purba , Urip Transna Putra
Published: May 2022

Penelitian ini bertujuan: a) menganalisa persepsi debitur terhadap implementasi KUR, b) menganalisa implementasi KUR terhadap pendapatan nasabah UMKM sebelum dan dan sesudah menerima KUR sektor usaha jasa dan sektor usaha perdagangan.  Untuk mencapai tujuan tersebut maka dipergunakan data primer dan data sekunder dengan runtun waktu dari tahun 2014 – 2016 yang dianalisis dengan menggunakan uji mean, uji standart deviasi, uji korelasi dan uji t hitung. Hasil penelitian ini mewujudkan bahwa persepsi nasabah terhadap implementasi KUR sudah efektif dengan total skor penilaian 1585 dari 1785 berarti sudah tercapai tujuan Bank Papua guna membantu UMKM. Dari hasil korelasi menunjukkan bahwa penyaluran KUR berpengaruh terhadap pendapatan nasabah sebelum dan sesudah menerima KUR, sektor usaha jasa diperoleh nilai t-hitung -6.087 > t-tabel 0,5 persen dan nilai p sebesar 0,000 (0.000<0,05) yang berarti ada perubahan peningkatan pendapatan nasabah signifikan, sektor usaha perdagangan diperoleh nilai t-hitung -10322 > t-tabel 0,5 persen dan nilai p sebesar 0,000 (0,0000<0,005) yang berarti ada perubahan peningkatan pendapatan nasabah signifikan.Kata kunci : UMKM, KUR, Sektor Usaha Jasa, Sektor Usaha Perdagangan, Pendapatan
Analisis Efisiensi Dan Efektifitas Pengelolaan Keuangan Daerah Guna Menunjang Kemandirian Fiskal Kabupaten Mamberamo Tengah
Authors: Jitmau Yuliana , Iek Mesak , Ngutra Risky Novan
Published: May 2022

Penelitian ini bertujuan untuk menganalisis Efisiensi dan Efektifitas Pengelolaan Keuangan Daerah Guna Menunjang Kemandirian Fiskal Daerah Kabupaten Mamberamo Tengah. Penelitian ini dilakukan di Badan Keuangan dan Aset Daerah Kabupaten Mamberamo Tengah pada pengelolaan dana Kabupaten periode 2012 - 2016. Tekhnik pengumpulan data menggunakan data primer yaitu melalui wawancara dan data sekunder menggunakan studi kepustakaan serta alat analisis Deskriptif.  Hasil penelitian menunjukan bahwa pengelolaan dana pemerintah daerah dengan efisien dan efektif akan berguna untuk menunjang kemandirian fiskal Daerah Kabupaten Mamberamo Tengah. Selain itu faktor pendukung dan penghambat pengelolaan dana pemerintah daerah dalam menunjang kemandirian fiskal daerah Kabupaten Mamberamo Tengah. Faktor pendukung yaitu lancarnya aliran dukungan dana yang mengalir ke pemerintah daerah Kabupaten dan penerapaan analisa standar belanja (ASB) serta faktor penghambat yaitu rendahnya SDM dan kurangnya infratruktur pendukung pengelolaan keuangan daerahKesimpulan : Keuangan Daerah,  Kemandirian Fiskal Daerah
Analisis Pemanfaatan Alokasi Dana Desa (ADD) Di Kampung Itakiwa Distrik Sentani Timur Kabupaten Jayapura
Authors: Jarollo Martha Maria , Urip Transna Putra , Marbun Robert M. WST.
Published: May 2022

Penelitian ini bertujuan untuk mengetahui apakah alokasi dana desa bidang penyelenggaran pemerintah, pembangunan desa, pemberdayaan masyarakat berpengaruh terhadap Pemanfaatan Alokasi Dana Desa (ADD). Penelitian ini menggunakan metode Pendekatan diskriptif kuantitatif. Dengan menggunakan teknik pengumpulan data melalui kuisioner. Dengan menggunakan teknik pengumpulan melalui kuisioner yang diberikan kepada informan yang di anggap dapat memberikan informasi tentang Pemanfaatan Alokasi dana desa. Penelitian ini dilakukan Dengan metode analisis Kriteria Interpretasi Skor. Hasil Pengolahan data ini ditemukan bahwa Dana Desa pada bidang Penyelenggaraan Pemerintah Kampung berpengaruh Baik terhadap Pemanfaatan ADD dengan presepsi skor 0,82, Pembangunan Kampung berpengaruh Baik terhadap pemanfaatan ADD dengan presepsi skor 0,73, Pemberdayaan masyarakat berpengaruh Baik terhadap Pemanfaatan ADD dengan presepsi skor 0,75. Hal ini menunjukkan di semua Bidang pada pemanfaatan ADD berpengaruh Baik. Dalam arti pemanfaatan ADD sudah bermanfaat terhadap kesejahteraan masyarakat dengan baik.Kata Kunci : Pemanfaatan, Alokasi Dana Desa, Pembangunan, Pemberdayaan
Analisis Pola Perdagangan Dan Tingkat Kesejahteraan Pedagang Lokal Di Wilayah Perbatasan RI-PNG
Authors: Sidabutar Alexander R. , Marlissa Elsyan R. , Siahainenia Joddy E. H. , Rumalutur Tince
Published: May 2022

Tujuan penelitian ini adalah untuk mengetahui, Pola perdagangan apa yang digunakan di wilayah pasar perbatasan RI-PNG, Konsumen terbanyak di wilayah pasar perbatasan RI-PNG, Berapa banyak frekuensi hari pasar yang terjadi dalam kurun waktu satu minggu, dan berapa banyak transaksi antara pedagang dan konsumen yang terjadi dalam satu hari pasar. Penelitian ini juga bertujuan untuk mengetahui Tingkat kesejahteraan pedagang dengan seberapa besar pendapatan yang di terima oleh setiap pedagang dalam satu hari pasar, berapa besar keuntungan bersih yang di terima oleh pedagang dalam kurun waktu satu minggu, berapa besar dari pendapatan bersih yang di terima oleh pedagang yang di gunakan untuk kebutuhan rumah tangga, biaya pendidikan, biaya kesehatan , dan kebutuhan lainnya berdasarkan jumlah anggota keluarga yang menjadi tanggungan dari setiap pedagang. Data yang digunakan dalam penelitian ini adalah data primer yang diperoleh langsung dari responden di lapangan dengan menggunakan kuisioner,didistribusikan kepada 30 responden, yaitu responden pedagang Orang Asli Papua sebanyak 4 reponden dan Non Papua sebanyak 26 responden. Metode analisis yang digunakan dalam menjawab tujuan penelitian ini menggunakan skala likert dan deskriptif kuantitatif. Hasil dari penelitian ini menunjukkan bahwa setiap pedagang baik itu Orang Asli Papua dan Non Papua yang berjualan di Wilayah Pasar Perbatasan ini mampu meraih kesejahteraan dengan masing-masing komoditi yang peredagangkan.Kata Kunci : Pola Perdagangan, Tingkat Kesejahteraan
Analisis Sektor Basis Pembangunan Wilayah Adat Mamta Di Provinsi Papua
Authors: Yegrim Brian Kristianto , Riani Ida Ayu Purba , Purwadi Marsi Adi
Published: May 2022

Penelitian ini bertujuan untuk mengetahui sektor mana saja yang menjadi sektor basis ekonomi Kabupaten/Kota di wilayah adat Mamta Provinsi Papua,untuk mengetahui perubahan pergeseran struktur ekonomi Kabupaten/Kota di wilayah adat Mamta di Provinsi Papua, untuk mengetahui model rasio pertumbuhan Kabupaten/Kota di Wilayah Adat Mamta Provinsi Papua, untuk mengetahui overlay Kabupaten/Kota di Wilayah Adat Mamta Provinsi Papua. Jenis data yang digunakan yaitu data sekunder berupa PDRB Kabupaten/Kota di wilayah adat Mamta menurut lapangan atas dasar harga konstan 2010. penelitian ini menggunakan beberapa metode analisis data antara lain; metode analisi yang digunakan yaitu Location Quotient (LQ), Shift-Share (S-S), Model Rasio Pertumbuhan (MRP),  dan Analisis Overlay. Berdasarkan hasil analisis yang mendapatkan sektor basis dari masing-masing kelima Kabupaten/Kota yang ada di wilayah adat Mamta, mendapati  bahwa sektor pertambangan dan penggalian merupakan sektor basis yang ada pada kelima Kabupaten/Kota baik itu Kota Jayapura, Kabupaten Jayapura, Kabupaten Sarmi, Kabupaten Keerom, maupun Kabupaten Mamberamo Raya. Dengan demikian maka dapat disimpulkan bahwa sektor pertambangan dan penggalian merupakan sektor basis untuk Kabupaten/Kota di wilayah Mamta.Kata Kunci : PDRB,  LQ, Shift-share, MRP, Overlay
An Analysis of Madrasah Aliyah Students’ Ability in Writing Recount Text
Authors: Hasanah Iradatul
Published: May 2022

Students' ability in writing varies greatly; some students can write recount text, but on the other hand, others don't have that capability. This study focus on five aspects of writing. They are Grammar, Vocabulary, Mechanic, Organization, and Fluency. This study aims to find out the ability of Tenth Grade Students of MAN 4 Kota Pekanbaru in writing recount text. The data collecting technique is using a writing test. The research findings are as follows: first, the Tenth Grade student of MAN 4 Kota Pekanbaru's ability to write recount text is at a good level with an average score of 64.75. Second, the student's average score in terms of Grammar is 61.80, Vocabulary is 69, Mechanic is 70.02, Organization is 61.80, and Fluency is 52.40. This component is the most challenging problem the students face in writing recount texts. This result concluded that the tenth-grade students of MAN 4 Pekanbaru have a relatively good level of writing recount texts. But with an average score of 62.75, they need to practice more in writing a text.
Gaya Bahasa Hiperbola dalam Novel Bumi Manusia Karya Pramoedya Ananta Toer
Authors: Aprila Tri Mike
Published: May 2022

Bumi Manusia is one of the best-seller novels works by Pramoedya Ananta Toer, which has many styles of hyperbole with exciting diction. Pramoedya Ananta Toer's fame as a novelist and his kind personality finally made this novel into a film in 2019. The specialty of this novel should be implemented as a life value, especially by teenagers today. This article aims to analyze the function and meaning of the hyperbole language style contained in the Bumi Manusia novel. This qualitative article used a descriptive method. The data were obtained from words related to hyperbole in this novel. The main instrument is the researcher himself, who uses this novel as a data source. Based on the analysis results, there are 94 hyperbolic language style data. So, it can be concluded that the stylistic function of hyperbole writers tends to apply poetic parts. Meanwhile, in aspects of the meaning of figurative languages, the author succeeds in using denotative and metaphorical meanings in telling the events.
Internalisasi Nilai-nilai Moderasi Beragama dalam Pembelajaran Fikih di Madrasah Aliyah
Authors: Tanjung Agus Salim
Published: May 2022

The cases of intolerance that are growing nowadays demand significant efforts from various parties. Madrasah Aliyah as an educational institution under the Ministry of Religious Affairs of the Republic of Indonesia which has a special distinction in teaching Islamic Religious Education has the responsibility to find out the alternatives to this problem. Therefore, this study aims to describe the design of internalizing religious moderation values in Fiqh learning at Madrasah Aliyah as a deradicalization effort. This study was carried out using a qualitative descriptive approach to get a complete picture of the various theories. In addition, sources of data from multiple pieces of literature were collected through documentation and analyzed using content analysis techniques. This study recommends that religious moderation values be internalized in Fiqh learning through at least four strategies: integration in learning plans, integration in learning materials, integration in the learning process, and integration in learning evaluation.
Model NURS sebagai Alternatif Pembelajaran Keterampilan Membaca Bahasa Arab
Authors: Cholid Cholid
Published: May 2022

Arabic as a second language has different characteristics for students in Indonesia. To master the competence of reading Arabic texts, students must first master the Arabic Grammar before trying to understand the text they are reading. Furthermore, learning Arabic is often considered a scourge by most students. For that reason, this article aims to describe the NURS learning model as a solution for learning Arabic reading skills. The approach used in writing this article is a qualitative descriptive approach. Data were collected through documentation techniques and analyzed using content analysis by Miles and Huberman's theory. The conclusion of this article reveals that the NURS teaching model was designed based on constructivism and humanistic theories. This concept aligns with contextual learning and teaching that integrates student life into the learning process and materials. In addition, this model also allows teachers to become facilitators so the students can explore all existing potential to achieve learning objectives.
AS TECNOLOGIAS DIGITAIS DA INFORMAÇÃO E COMUNICAÇÃO: UMA ANÁLISE DOCUMENTAL NA BASE NACIONAL COMUM CURRICULAR DO ENSINO MÉDIO
Authors: Pacitti Mirella Horvatte , Tardin Heitor Perrud , Romero Luiz Rogério
Published: May 2022

The aim of this article is to identify in the National Common Curricular Base (BNCC) of High School how the Digital Information and Communication Technologies (TDIC) are being mentioned and to discuss whether these mentions are sufficient to contemplate critical media education for Teaching Average. Digital language is present in society and should be explored as a means of communication, information, interactivity and especially as a way of conceiving new devices. Therefore, it is expected that High School will offer subsidies to use and reflect on these technologies since they are increasingly present in the daily lives of young people. As a methodology, the document analysis of the BNCC was applied using the Adobe Acrobat Reader DC software, using the Word Search command “Ctrl + F”. The search resulted in only eleven mentions in the part destined to High School, and most of these mentions are located in the Area of Languages and its Technologies. Based on the evidence provided by the literature, the importance of the document and the relevance of TIDC's in today's society, it is concluded that the chosen theme needs qualitative and quantitative expansion in the BNCC. Technologies are important parts of contemporary reality and their value is increasingly proven, whether scientifically or in everyday use, but this study is limited to the documentary field, since no observational research was carried out.
Perspective Chapter: Advances in the Development of Anti-Trichinella spiralis Vaccine, Challenges, and Future Prospective
Authors: Tahir Aleem Muhammad , Yan Ruofeng , Khan Asad , Asrar Rida , Shakoor Amna , Asif Areej , Wen Zhaohai , Yu Zhengqing , Abdullah Malik Muhammad , Tauseef-ur-Rehman  , Zahid Abbas Rao , Mohsin Muhammad , Song Xiaokai , Xu Lixin , Li Xiangrui
Published: May 2022

Trichinellosis is a food-borne, zoonotic disease that causes infection by a nematode parasite belonging to the genus Trichinella. This is an important disease, and its causative agent is prevalent throughout the world (cosmopolitan). More clinical awareness of trichinellosis is required due to its many outbreaks, increase in the consumption of pork meat and its by-products. Trichinellosis is an epizootic in nature and its economic burden is associated with the prevention of this disease from the human food chain. This disease is transmitted from animals to humans through the consumption of raw or undercooked meat containing encapsulated muscle larvae of Trichinella spiralis. This paper demonstrates the direct effect of progesterone (P4) and mifepristone (RU486) on the progesterone receptors of T. spiralis. Also, studied the challenges in the preparation of DNA and recombinant protein vaccination to control trichinellosis. It is simply done this study at different life cycle developmental stages of T. spiralis. Vaccines development against T. spiralis infection is the new paradime shift from prevention of trichinellosis to fulfilling the food safety requirements.
Shear Wave Elastography in the Assessment of Liver Changes in Children with Cystic Fibrosis
Authors: Pykov Mikhail , Kuzmina Natalia , Rostovtsev Nikolay
Published: May 2022

A standard ultrasound examination of the liver was performed in 232 children. It was supplemented by a two-dimensional shear wave elastography. There were 200 healthy children aged 3 to 18 years (control group) and 32 patients with cystic fibrosis aged 2 to 17 years (study group) among them. The procedure was carried out by means of Aixplorer device (Supersonic Imagine, France) using a convex sensor operating in the 1–6 MHz frequency range. Ten measurements of Young modulus values were carried out in different segments of the right lobe of the liver followed by data averaging. In patients with cystic fibrosis, the values of Young modulus were significantly higher than in healthy children (Emean median: 6.50 and 5.00 kPa, interquartile range: 5.62–7.52 and 4.70–5.38 kPa, respectively (p < 0.001). In patients with severe cystic fibrosis, the values of Young modulus were significantly higher compared to patients suffering from moderate disease (Emean median: 7.30 and 5.90 kPa, interquartile range: 6.20–10.70 and 5.20–6.75 kPa, respectively (p < 0.002). Shear wave elastography is a non-invasive technique that can be successfully used in a comprehensive ultrasound assessment of the liver in children with cystic fibrosis to facilitate the diagnosis and monitoring of fibrous changes.
Genetic Transformation in Prokaryotic and Eukaryotic Cells
Authors: Semiarti Endang , Asih Purwestri Yekti , Rohman Saifur , Aristyaning Putri Wahyu
Published: May 2022

Improving the quality and quantity of an organism and its products can be approached by molecular characters enhancement through the insertion of a gene of interest into cells of the desired organism. Genetic transformation of an organism involves isolation, identification, cloning a gene of interest into a vector, and transferring the gene to the target organism. This chapter reviews the process of genetic transformation into the organism’s cell from bacterial (Escherichia coli), yeast, plant (Onion, Tobacco, and Orchids), and mammalian. The discussion will be focused on the introduction of DNA molecules into plant cells and protoplast mediated by polyethylene glycol (PEG), electroporation, and gene gun using particle bombardment. Further discussion on the transient protein expression system of plant-based on protoplast, onion cell, and tobacco will also be covered in this chapter as well. The systems have been proven as a powerful tool for determining subcellular protein localization, protein-protein interactions, identifying gene function, and regulation. Finally, it can be clearly seen, the differences and similarities in the mechanism of genetic transformation both in prokaryotic and eukaryotic systems.
The Function of a Coffee Shop as a Social Cultural Entity
Authors: Hakim Maksud , Syahban Amir Ali
Published: May 2022

This book chapter aims to determine the process of changing the meaning of a coffee shop from traditional to modern, to find out the change in the meaning of a coffee shop as a space for socio-cultural entities, and to find out the change in the meaning of a coffee shop as an effective political tool. This book chapter uses a naturalistic (qualitative) paradigm approach to analyze and construct the change in the meaning of a coffee shop as a space for socio-cultural entities in the municipality of Makassar, South Sulawesi. The selection of this location is based on the consideration that Makassar Municipality is a large city that has a heterogeneous population. This book chapter shows that the change in the meaning of traditional coffee shops to modern coffee shops is characterized by simple facilities that develop into public spaces equipped with facilities and information such as television, newspapers, and internet networks to meet the needs and satisfaction of visitors. Coffee shops have become a socio-cultural entity. Coffee shops have been used as a means of political discussion and self-image, both formally and informally, socialization of work programs with political figures or authorities, and digging information effectively from visitors.
Ethnomedicinal Appraisal of Traditionally Used Wild Edible Plants of District Bagh, Azad Jammu and Kashmir, Pakistan
Authors: Shabbir Sadia , Shoaib Amjad Muhammad
Published: May 2022

The present study was aim to document the traditional knowledge about medicinal uses of wild edible plants in District Bagh Azad Kashmir. Ethnomedicinal data was gathered from 80 informants using open ended and semi structured interview, field observation and group discussion. A total of 51 wild edible plant species mentioned by informants’ as medicinal belonging to 42 botanical genera and 32 botanical families with Legumenaceae (6 spp.) and Rosaceae (5 spp.) being most frequently used. Herbs (45.09%) were most commonly used for prepration of herbal recipies. The preferably used plant part for herbal preparation are leaves (64.7%). The plant species with highest relative frequency of citation are Morus nigra (0.9) and Melia azedarach (0.9). The highest UV values was recorded for M. nigra (1) and Berberis lycium (1). The highest RI value was calculated for Urginea indica (90). Berberis lycium had 100% fidelity level. Wild edible plants species are under high anthropogenic pressure and need immediate conservation through community base management, public awareness and germplasm collection. There is dire need for reappraisal of traditionally knowledge on wild edible plants which not only conserve this traditional heritage but may also contribute in future drug discovery.
Application of Jump Diffusion Models in Insurance Claim Estimation
Authors: Mushunje Leonard , Elvina Mashiri Chiedza , Chandiwana Edina , Mashasha Maxwell
Published: May 2022

We investigated if general insurance claims are normal or rare events through systematic, discontinuous or sporadic jumps of the Brownian motion approach and Poisson processes. Using firm quarterly data from March 2010 to December 2018, we hypothesized that claims with high positive (negative) slopes are more likely to have large positive (negative) jumps in the future. As such, we expected salient properties of volatile jumps on the written products/contracts. We found that insurance claims for general insurance quoted products cease to be normal. There exist at times some jumps, especially during holidays and weekends. Such jumps are not healthy to the capital structures of firms, as such they need attention. However, it should be noted that gaps or jumps (unless of specific forms) cannot be hedged by employing internal dynamic adjustments. This means that, jump risk is non-diversifiable and such jumps should be given more attention.
Radically Hopeful Civic Engagement
Authors: Hole Benjamin , Janzen Monica , Ilea Ramona C. ,   Philosophy Documentation Center
Published: May 2022

Tragedy feels disempowering and the confluence of tragedies since the beginning of 2020 can overwhelm one’s sense of agency. This paper describes how we use a civic engagement (CE) project to nurture radical hope for our students. Radical hope involves a desire for a positive outcome surpassing understanding, as well as an activity to strive to achieve that outcome despite its uncertainty. Our CE project asks students to identify ethical issues they care about and respond in a fitting way, questioning the assumption that their efforts do not matter, and imagining creative ways to make a difference that are in their power. We scaffold our CE project in order to nurture hopeful possibilities for students by offering real-world, feasible pathways for addressing systemic problems.
The first Arctic conspicuously coloured Pleusymtes (Crustacea: Amphipoda: Pleustidae) associated with sea anemones in the Barents Sea
Authors: Marin Ivan N. , Sinelnikov Sergey Yu. , Antokhina Tatiana I.
Published: May 2022

The article presents a potentially obligate association of a pleustid amphipod of the genus Pleusymtes (Crustacea: Amphipoda: Pleustidae) with the large sea anemone Urticina eques (Gosse, 1858) (Anthozoa: Actiniaria: Actiniidae) from shallow waters of the Barents Sea. The new species shows a conspicuously striped (disruptive or aposematic) colouration, unlike other Arctic species of the genus, which shows a potential for its permanent connection with anemones. It is possible that this is the first known possibly obligatory anemone-associated species, within the genus and the family Pleustidae. The article discusses the taxonomy, morphological differences from congeners and ecological features of the new species, as well as the known symbiotic associations of sea anemones (as hosts) in Arctic and sub-Arctic waters.