bluuebunny/crossref_metadata_2025 huggingface dataset:
Laser Cladding In-Situ Ti(C,N) Particles Reinforced Ni-Based Composite Coatings Modified with CeO2 Nanoparticles
Authors: Chen Tao , Wu Fan , Wang Haojun , Liu Defu
Published: August 2018

To improve the wear resistance of titanium alloy parts used in the engineering applications, in-situ formed Ti(C,N) particles reinforcing Ni-based composite coatings are fabricated on Ti6Al4V alloys by the laser cladding technique using Ni60, C, TiN, and small amounts of CeO2 nanoparticles mixed powders as the pre-placed materials. Firstly, the formation mechanism of Ti(C,N) particles as a reinforced phase in the coating is investigated. Then, the influences of CeO2 nanoparticles on microstructures and wear resistance of the coatings are analyzed. It is indicated that the large Ti(C,N) particles form around TiN particles, and the small Ti(C,N) particles form through independent nucleation. CeO2 nanoparticles play important roles in increasing the nucleation rate and improving the precipitation of Ti(C,N), hence the microstructures and wear resistance of the coatings are apparently improved after adding CeO2 nanoparticles. It is observed that the 1 wt % content of CeO2 additive in the pre-placed powders is the best choice for the wear resistance of the coatings.
Corrosion, Erosion and Wear Behavior of Complex Concentrated Alloys: A Review
Authors: Ayyagari Aditya , Hasannaeimi Vahid , Grewal Harpreet Singh , Arora Harpreet , Mukherjee Sundeep
Published: August 2018

There has been tremendous interest in recent years in a new class of multi-component metallic alloys that are referred to as high entropy alloys, or more generally, as complex concentrated alloys. These multi-principal element alloys represent a new paradigm in structural material design, where numerous desirable attributes are achieved simultaneously from multiple elements in equimolar (or near equimolar) proportions. While there are several review articles on alloy development, microstructure, mechanical behavior, and other bulk properties of these alloys, then there is a pressing need for an overview that is focused on their surface properties and surface degradation mechanisms. In this paper, we present a comprehensive view on corrosion, erosion and wear behavior of complex concentrated alloys. The effect of alloying elements, microstructure, and processing methods on the surface degradation behavior are analyzed and discussed in detail. We identify critical knowledge gaps in individual reports and highlight the underlying mechanisms and synergy between the different degradation routes.
Assessment of the Deformability and Velocity of Healthy and Artificially Impaired Red Blood Cells in Narrow Polydimethylsiloxane (PDMS) Microchannels
Authors: Boas Liliana Vilas , Faustino Vera , Lima Rui , Miranda João Mário , Minas Graça , Fernandes Carla Sofia Veiga , Catarino Susana Oliveira
Published: August 2018

Malaria is one of the leading causes of death in underdeveloped regions. Thus, the development of rapid, efficient, and competitive diagnostic techniques is essential. This work reports a study of the deformability and velocity assessment of healthy and artificially impaired red blood cells (RBCs), with the purpose of potentially mimicking malaria effects, in narrow polydimethylsiloxane microchannels. To obtain impaired RBCs, their properties were modified by adding, to the RBCs, different concentrations of glucose, glutaraldehyde, or diamide, in order to increase the cells’ rigidity. The effects of the RBCs’ artificial stiffening were evaluated by combining image analysis techniques with microchannels with a contraction width of 8 µm, making it possible to measure the cells’ deformability and velocity of both healthy and modified RBCs. The results showed that healthy RBCs naturally deform when they cross the contractions and rapidly recover their original shape. In contrast, for the modified samples with high concentration of chemicals, the same did not occur. Additionally, for all the tested modification methods, the results have shown a decrease in the RBCs’ deformability and velocity as the cells’ rigidity increases, when compared to the behavior of healthy RBCs samples. These results show the ability of the image analysis tools combined with microchannel contractions to obtain crucial information on the pathological blood phenomena in microcirculation. Particularly, it was possible to measure the deformability of the RBCs and their velocity, resulting in a velocity/deformability relation in the microchannel. This correlation shows great potential to relate the RBCs’ behavior with the various stages of malaria, helping to establish the development of new diagnostic systems towards point-of-care devices.
Textural Characteristics of Noncrystalline Silica in Sinters and Quartz Veins: Implications for the Formation of Bonanza Veins in Low-Sulfidation Epithermal Deposits
Authors: Taksavasu Tadsuda , Monecke Thomas , Reynolds T. James
Published: August 2018

Silica sinters forming at the Wairakei geothermal power plant in New Zealand are composed of noncrystalline opal-A that deposited rapidly from cooling geothermal liquids flashed to atmosphere. The sinter is laminated with alternating layers of variably compacted silicified filamentous microbes encased by chains of fused silica microspheres. Microscopic inspection of bonanza quartz vein samples from the Buckskin National low-sulfidation epithermal precious metal deposit in Nevada showed that colloform bands in these veins exhibit relic microsphere textures similar to those observed in the silica sinters from the Wairakei power plant. The textural similarity suggests that the colloform bands were originally composed of noncrystalline opal-A that subsequently recrystallized to quartz. The colloform bands contain dendrites of electrum and naumannite that must have grown in a yielding matrix of silica microspheres deposited at the same time as the ore minerals, implying that the noncrystalline silica exhibited a gel-like behavior. Quartz bands having other textural characteristics in the crustiform veins lack ore minerals. This suggests that ore deposition and the formation of the colloform bands originally composed of compacted microspheres of noncrystalline silica are genetically linked and that ore deposition within the bonanza veins was only episodic. Supersaturation of silica and precious metals leading to the formation of the colloform bands may have occurred in response to transient flashing of the hydrothermal liquids. Flashing of geothermal liquids may thus represent a key mechanism in the formation of bonanza precious metal grades in low-sulfidation epithermal deposits.
Simultaneous Analysis of 20 Mycotoxins in Grapes and Wines from Hexi Corridor Region (China): Based on a QuEChERS–UHPLC–MS/MS Method
Authors: Zhang Bo , Chen Xia , Han Shun-Yu , Li Min , Ma Teng-Zhen , Sheng Wen-Jun , Zhu Xia
Published: August 2018

The aim of this study is to develop and validate an improved analytical method for the simultaneous quantification of 20 types of mycotoxins in grapes and wines. In this research, the optimization of tandem mass spectrometer (MS/MS) parameter, ultra-high pressure liquid chromatography (UHPLC) separation, and QuEChERS procedure, which includes wine/water ratio, the amount and type of salt, clean-up sorbent, were performed, and the whole separation of mycotoxins was accomplished within 7 min analyzing time. Under optimum conditions, recoveries ranged from 85.6% to 117.8%, while relative standard deviation (RSD) remained between 6.0% and 17.5%. The limit of detection (LOD, 0.06–10 μg/L) and the limit of quantification (LOQ, 0.18–30 μg/L) were lower than those permitted by legislation in food matrices, which demonstrated the high sensitivity and applicability of this efficient method. Finally, 36 grapes and 42 wine samples from the Hexi Corridor region were analyzed. Penicillic acid (PCA), mycophenolic acid (MPA), cyclopiazonic acid (CPA), fumonisin B1 (FB1) and zearalenone (ZEN) were detected in a small number of grape samples with lower concentrations between 0.10 μg/L and 81.26 μg/L. Meanwhile, ochratoxin A (OTA), aflatoxin B2 (AFB2), MPA, CPA, and ZEN were detected in some wine counterparts with concentrations ranged from 0.10 μg/L to 4.62 μg/L. However, the concentrations of the detected mycotoxins were much lower than the maximum legal limits set of other products.
In Vivo Brain Imaging, Biodistribution, and Radiation Dosimetry Estimation of [11C]Celecoxib, a COX-2 PET Ligand, in Nonhuman Primates
Authors: Kumar J. S. Dileep , Bai Bing , Zanderigo Francesca , DeLorenzo Christine , Prabhakaran Jaya , Parsey Ramin V. , Mann J. John
Published: August 2018

COX-2 selective inhibitors (COXIBs) are non-steroidal anti-inflammatory drugs (NSAIDs), with fewer side effects compared with non-selective NSAIDs, and are used for the treatment of arthritis, headaches, and other inflammatory diseases of the brain and peripheral tissues. Radiolabeled COXIBs may permit positron emission tomography (PET) imaging of COX-2 localization and activity in diseases, enable monitoring of inflammatory processes, and determine target occupancy of COX-2 activity by NSAIDs, thus, accelerating the development of novel CIXIBs. We synthesized [11C]celecoxib, one of the COXIBs and a prescription drug, and here report its in vivo uptake in the brain, whole body biodistribution, and radiation dosimetry in baboons using PET. Brain imaging experiments were performed in one baboon and whole body PET scans were performed in triplicates in two male baboons using an ECAT ACCEL (Siemens Medical Solutions, Inc. Knoxville) under anesthetic conditions. PET studies in baboons show that [11C]celecoxib penetrates the blood brain barrier (BBB) and accumulates in the brain, followed by a washout of radioactivity. The liver has the highest residence time and the gallbladder is the critical organ for [11C]celecoxib. Organ Level Internal Dose Assessment (OLINDA) estimates indicate that the maximum permissible single study dosage of [11C]celecoxib in humans is 1110 MBq (30 mCi) for both males and females under the 21 CFR 361.1 dose limit for research subjects.
Kinetic Characterization of Novel HIV-1 Entry Inhibitors: Discovery of a Relationship between Off-Rate and Potency
Authors: Meuser Megan E. , Murphy Michael B. , Rashad Adel A. , Cocklin Simon
Published: August 2018

The entry of HIV-1 into permissible cells remains an extremely attractive and underexploited therapeutic intervention point. We have previously demonstrated the ability to extend the chemotypes available for optimization in the entry inhibitor class using computational means. Here, we continue this effort, designing and testing three novel compounds with the ability to inhibit HIV-1 entry. We demonstrate that alteration of the core moiety of these entry inhibitors directly influences the potency of the compounds, despite common proximal and distal groups. Moreover, by establishing for the first time a surface plasmon resonance (SPR)-based interaction assay with soluble recombinant SOSIP Env trimers, we demonstrate that the off-rate (kd) parameter shows the strongest correlation with potency in an antiviral assay. Finally, we establish an underappreciated relationship between the potency of a ligand and its degree of electrostatic complementarity (EC) with its target, the Env complex. These findings not only broaden the chemical space in this inhibitor class, but also establish a rapid and simple assay to evaluate future HIV-1 entry inhibitors.
Functional Group Effects on the HOMO–LUMO Gap of g-C3N4
Authors: Li Hao , Zhang Zhien , Liu Yulu , Cen Wanglai , Luo Xubiao
Published: August 2018

Graphitic carbon nitride (g-C3N4) is a promising semiconductor material which has been widely studied in nanoscience. However, the effect of modifying the performance of g-C3N4 is still under debate. In this communication, we show the size and functional group effects on the g-C3N4 using density functional theory (DFT) calculations. It was found that a molecule with six repeated g-C3N4 units (g-C3N4-6) could be the smallest unit that converges to the limit of its HOMO–LUMO gap. Calculations of g-C3N4-6 with varying numbers of substituted C≡N, C=O, and O−H functional groups show that C≡N and C=O could narrow down the HOMO–LUMO gap, while O−H could slightly raise the gap. This study shows that the change of substituents could tune the band gap of g-C3N4, suggesting that rationally modifying the substituent at the edge of g-C3N4-based materials could help to significantly increase the photocatalytic properties of a metal-free g-C3N4.
Controllable Synthesis of 2D Perovskite on Different Substrates and Its Application as Photodetector
Authors: Xue Yunzhou , Yuan Jian , Liu Jingying , Li Shaojuan
Published: August 2018

Perovskites have recently attracted intense interests for optoelectronic devices application due to their excellent photovoltaic and photoelectric properties. The performance of perovskite-based devices highly depends on the perovskite material properties. However, the widely used spin-coating method can only prepare polycrystalline perovskite and physical vapor deposition (PVD) method requires a higher melting point (>350 °C) substrate due to the high growth temperature, which is not suitable for low melting point substrates, especially for flexible substrates. Here, we present the controlled synthesis of high quality two-dimensional (2D) perovskite platelets on random substrates, including SiO2/Si, Si, mica, glass and flexible polydimethylsiloxane (PDMS) substrates, and our method is applicable to any substrate as long as its melting point is higher than 100 °C. We found that the photoluminescence (PL) characteristics of perovskite depend strongly on the platelets thickness, namely, thicker perovskite platelet has higher PL wavelength and stronger intensity, and thinner perovskite exhibits opposite results. Moreover, photodetectors based on the as-produced perovskite platelets show excellent photoelectric performance with a high photoresponsivity of 8.3 A·W−1, a high on/off ratio of ~103, and a small rise and decay time of 30 and 50 ms, respectively. Our approach in this work provides a feasible way for making 2D perovskite platelets for wide optoelectronic applications.
The Effects of Alcohol and Drugs of Abuse on Maternal Nutritional Profile during Pregnancy
Authors: Sebastiani Giorgia , Borrás-Novell Cristina , Alsina Casanova Miguel , Pascual Tutusaus Mireia , Ferrero Martínez Silvia , Gómez Roig María Dolores , García-Algar Oscar
Published: August 2018

The consumption of alcohol and drugs of abuse among pregnant women has experienced a significant increase in the last decades. Suitable maternal nutritional status is crucial to maintain the optimal environment for fetal development but if consumption of alcohol or drugs of abuse disrupt the intake of nutrients, the potential teratogenic effects of these substances increase. Despite evidence of the importance of nutrition in addicted pregnant women, there is a lack of information on the effects of alcohol and drugs of abuse on maternal nutritional status; so, the focus of this review was to provide an overview on the nutritional status of addicted mothers and fetuses. Alcohol and drugs consumption can interfere with the absorption of nutrients, impairing the quality and quantity of proper nutrient and energy intake, resulting in malnutrition especially of micronutrients (vitamins, omega–3, folic acid, zinc, choline, iron, copper, selenium). When maternal nutritional status is compromised by alcohol and drugs of abuse the supply of essential nutrients are not available for the fetus; this can result in fetal abnormalities like Intrauterine Growth Restriction (IUGR) or Fetal Alcohol Spectrum Disorder (FASD). It is critical to find a strategy to reduce fetal physical and neurological impairment as a result of prenatal alcohol and drugs of abuse exposure combined with poor maternal nutrition. Prenatal nutrition interventions and target therapy are required that may reverse the development of such abnormalities.
Effects of Magnesium Supplementation on Unipolar Depression: A Placebo-Controlled Study and Review of the Importance of Dosing and Magnesium Status in the Therapeutic Response
Authors: Ryszewska-Pokraśniewicz Beata , Mach Anna , Skalski Michał , Januszko Piotr , Wawrzyniak Zbigniew M. , Poleszak Ewa , Nowak Gabriel , Pilc Andrzej , Radziwoń-Zaleska Maria
Published: August 2018

Animal studies using tests and models have demonstrated that magnesium exerts an antidepressant effect. The literature contains few studies in humans involving attempts to augment antidepressant therapy with magnesium ions. The purpose of our study was to assess the efficacy and safety of antidepressant treatment, in combination with magnesium ions. A total of 37 participants with recurrent depressive disorder who developed a depressive episode were included in this study. As part of this double-blind study, treatment with the antidepressant fluoxetine was accompanied with either magnesium ions (120 mg/day as magnesium aspartate) or placebo. During an 8-week treatment period, each patient was monitored for any clinical abnormalities. Moreover, serum fluoxetine and magnesium levels were measured, and pharmaco-electroencephalography was performed. The fluoxetine + magnesium and fluoxetine + placebo groups showed no significant differences in either Hamilton Depression Rating Scale (HDRS) scores or serum magnesium levels at any stage of treatment. Multivariate statistical analysis of the whole investigated group showed that the following parameters increased the odds of effective treatment: lower baseline HDRS scores, female gender, smoking, and treatment augmentation with magnesium. The parameters that increased the odds of remission were lower baseline HDRS scores, shorter history of disease, the presence of antidepressant-induced changes in the pharmaco-EEG profile at 6 h after treatment, and the fact of receiving treatment augmented with magnesium ions. The limitation of this study is a small sample size.
Retinoic Acid, Leaky Gut, and Autoimmune Diseases
Authors: Abdelhamid Leila , Luo Xin
Published: August 2018

A leaky gut has been observed in a number of autoimmune diseases including type 1 diabetes, multiple sclerosis, inflammatory bowel disease, and systemic lupus erythematosus. Previous studies from our laboratory have shown that lupus mice also bear a leaky gut and that the intestinal barrier function can be enhanced by gut colonization of probiotics such as Lactobacillus spp. Retinoic acid (RA) can increase the relative abundance of Lactobacillus spp. in the gut. Interestingly, RA has also been shown to strengthen the barrier function of epithelial cells in vitro and in the absence of probiotic bacteria. These reports bring up an interesting question of whether RA exerts protective effects on the intestinal barrier directly or through regulating the microbiota colonization. In this review, we will discuss the roles of RA in immunomodulation, recent literature on the involvement of a leaky gut in different autoimmune diseases, and how RA shapes the outcomes of these diseases.
Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation
Authors: Shrestha Riya , Cho Pil Joung , Paudel Sanjita , Shrestha Aarajana , Kang Mi Jeong , Jeong Tae Cheon , Lee Eung-Seok , Lee Sangkyu
Published: August 2018

Loxoprofen, a propionic acid derivative, non-steroidal anti-inflammatory drug (NSAID) is a prodrug that is reduced to its active metabolite, trans-alcohol form (Trans-OH) by carbonyl reductase enzyme in the liver. Previous studies demonstrated the hydroxylation and glucuronidation of loxoprofen. However, the specific enzymes catalyzing its metabolism have yet to be identified. In the present study, we investigated metabolic enzymes, such as cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT), which are involved in the metabolism of loxoprofen. Eight microsomal metabolites of loxoprofen were identified, including two alcohol metabolites (M1 and M2), two mono-hydroxylated metabolites (M3 and M4), and four glucuronide conjugates (M5, M6, M7, and M8). Based on the results for the formation of metabolites when incubated in dexamethasone-induced microsomes, incubation with ketoconazole, and human recombinant cDNA-expressed cytochrome P450s, we identified CYP3A4 and CYP3A5 as the major CYP isoforms involved in the hydroxylation of loxoprofen (M3 and M4). Moreover, we identified that UGT2B7 is the major UGT isoform catalyzing the glucuronidation of loxoprofen and its alcoholic metabolites. Further experimental studies should be carried out to determine the potency and toxicity of these identified metabolites of loxoprofen, in order to fully understand of mechanism of loxoprofen toxicity.
Impact of Clinical Decision Support on Time to Order Resolution for Patients with Documented Allergies
Authors: Watkins Tenielle , Aguero Sandra M. , Jaecks Michael
Published: August 2018

Failure to appropriately document patient medical information, such as allergies, is an important cause of medication errors. Lack of allergy details in the electronic medical record (EMR) may prolong the pharmacist order verification process. A retrospective chart review was conducted in October 2017, to evaluate the impact of incomplete allergy details on time to antibiotic order resolution at the Einstein Medical Center Philadelphia. Details were present on 71% of orders. The difference in median time to order resolution, for orders with versus without details, was –21 min (95% CI (confidence interval), –39 to –2.9; p = 0.02). The difference in median time to order resolution for orders, based on pharmacist work shift was, –21 min for the first shift (95% CI, –41.2 to –0.8; p = 0.04), –50 min for the second shift (95% CI, –109.8 to 9.8; p = 0.10), and +3 min for the third shift (95% CI, –36.1 to 30.1; p = 0.85). Orders with an allergy intervention by a pharmacist were 2.75 times more likely (adjusted odds ratio = 2.75; 95% CI, 0.98 to 7.7; p = 0.06) to have a therapy change than orders without allergy interventions. Based on the results, when information about antibiotic allergies lacks details, it takes more time for pharmacists to resolve alerted orders.
A Novel Technique for Fiber Formation: Mechanotropic Spinning—Principle and Realization
Authors: Kulichikhin Valery G. , Skvortsov Ivan Yu. , Subbotin Andrey V. , Kotomin Sergey V. , Malkin Alexander Ya.
Published: August 2018

We present basic experimental data and the theoretical background of a novel technique for fiber spinning from polymer solutions. The principal feature of the advanced process is realization of phase separation with detachment of a solvent, accompanied by the orientation of macromolecules, under the action of high extension rates. This is similar in some respects to dry spinning, though the driving force is not diffusion with subsequent evaporation of a solvent but redistribution of polymer-solvent interactions in favor of polymer-polymer and solvent-solvent ones governed by mechanical stresses. A promise of this approach has been demonstrated by experiments performed with polyacrylonitrile solutions in different solvents and solutions of the rigid-chain aromatic polyamide. We examined mechanotropic fiber spinning in model experiments with stretching jets from a drop of polymer solution in different conditions, and then demonstrated the possibility of realizing this process in the stable long-term continuous mode. During extension, phase separation happens throughout the whole section of a jet, as was confirmed by visual observation. Then a solvent diffuses on a jet surface, forming a liquid shell on the oriented fiber. Instability of this cover due to surface tension leads either to formation of separate solvent drops “seating” on the fiber or to the flow of a solvent down to the Taylor cone. The separate liquid droplets can be easily taken off a fiber. The physics underlying this process is related to the analysis of the influence of macromolecule coil-to-stretched chain transition on the intermolecular interaction.
Synthesis of Poly(ε-caprolactone)-Based Miktoarm Star Copolymers through ROP, SA ATRC, and ATRP
Authors: Sathesh Venkatesan , Chen Jem-Kun , Chang Chi-Jung , Aimi Junko , Chen Zong-Cheng , Hsu Yu-Chih , Huang Yi-Shen , Huang Chih-Feng
Published: August 2018

The synthesis of novel branched/star copolymers which possess unique physical properties is highly desirable. Herein, a novel strategy was demonstrated to synthesize poly(ε-caprolactone) (PCL) based miktoarm star (μ-star) copolymers by combining ring-opening polymerization (ROP), styrenics-assisted atom transfer radical coupling (SA ATRC), and atom transfer radical polymerization (ATRP). From the analyses of gel permeation chromatography (GPC), proton nuclear magnetic resonance (1H NMR), and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), well-defined PCL-μ-PSt (PSt: polystyrene), and PCL-μ-PtBA (PtBA: poly(tert-butyl acrylate) μ-star copolymers were successfully obtained. By using atomic force microscopy (AFM), interestingly, our preliminary examinations of the μ-star copolymers showed a spherical structure with diameters of ca. 250 and 45 nm, respectively. We successfully employed combinations of synthetic techniques including ROP, SA ATRC, and ATRP with high effectiveness to synthesize PCL-based μ-star copolymers.
Molecular Dynamics of Functional Azide-Containing Acrylic Films
Authors: Carsí Marta , Sanchis Maria J. , Vallejos Saul , García Félix C. , García José Miguel
Published: August 2018

A report on the syntheses, thermal, mechanical and dielectric characterizations of two novel polymeric acrylic materials with azide groups in their pendant structures is presented. Having the same general structure, these polymers differ in length of oxyethylene units in the pendant chain [-CONH-CH2CH2-(O-CH2CH2)nN3], where n is 1 (poly(N-(2-(2-azidoethoxy)ethyl)methacrylamide), PAzMa1) or 2 (poly(N-2-(2-(2-azidoethoxy)ethoxy)ethyl)methacrylamide), PAzMa2), leading with changes in their dynamics. As the thermal decomposition of the azide group is observed above 100 °C, dielectric analysis was carried out in the temperature range of −120 °C to 100 °C. Dielectric spectra of both polymers exhibit in the glassy state two relaxations labelled in increasing order of temperature as γ- and β-processes, respectively. At high temperatures and low frequencies, the spectra are dominated by ohmic conductivity and interfacial polarization effects. Both, dipolar and conductive processes were characterized by using different models. Comparison of the dielectric activity obtained for PAzMa1 and PAzMa2 with those reported for crosslinked poly(2-ethoxyethylmethacrylate) (CEOEMA) was performed. The analysis of the length of oxyethylene pendant chain and the effect of the methacrylate or methacrylamide nature on the dynamic mobility was analysed.
Seabed Mapping in Coastal Shallow Waters Using High Resolution Multispectral and Hyperspectral Imagery
Authors: Marcello Javier , Eugenio Francisco , Martín Javier , Marqués Ferran
Published: August 2018

Coastal ecosystems experience multiple anthropogenic and climate change pressures. To monitor the variability of the benthic habitats in shallow waters, the implementation of effective strategies is required to support coastal planning. In this context, high-resolution remote sensing data can be of fundamental importance to generate precise seabed maps in coastal shallow water areas. In this work, satellite and airborne multispectral and hyperspectral imagery were used to map benthic habitats in a complex ecosystem. In it, submerged green aquatic vegetation meadows have low density, are located at depths up to 20 m, and the sea surface is regularly affected by persistent local winds. A robust mapping methodology has been identified after a comprehensive analysis of different corrections, feature extraction, and classification approaches. In particular, atmospheric, sunglint, and water column corrections were tested. In addition, to increase the mapping accuracy, we assessed the use of derived information from rotation transforms, texture parameters, and abundance maps produced by linear unmixing algorithms. Finally, maximum likelihood (ML), spectral angle mapper (SAM), and support vector machine (SVM) classification algorithms were considered at the pixel and object levels. In summary, a complete processing methodology was implemented, and results demonstrate the better performance of SVM but the higher robustness of ML to the nature of information and the number of bands considered. Hyperspectral data increases the overall accuracy with respect to the multispectral bands (4.7% for ML and 9.5% for SVM) but the inclusion of additional features, in general, did not significantly improve the seabed map quality.
Fog and Low Cloud Frequency and Properties from Active-Sensor Satellite Data
Authors: Cermak Jan
Published: August 2018

An analysis of fog and low cloud properties and distribution is performed using satellite-based LiDAR. Recent years have seen great progress in the remote sensing of fog and low clouds using passive satellite-based sensors. On this basis, maps of fog distribution and frequency as well as baseline climatologies have been constructed. However, no information on fog altitude and vertical extent is available in this way, and fog/low cloud below other clouds cannot be detected in most cases. In this study, ten years of observations by the LiDAR aboard the CALIPSO (Cloud-Aerosol LiDAR and Pathfinder Satellite Observations) platform are used to construct a map and statistical evaluations of fog/low cloud distribution and properties. For the purpose of evaluation, a comparison is made to an evaluation of fog/low cloud distribution in Europe, derived from Meteosat measurements using the Satellite-Based Operation Fog Observation Scheme (SOFOS). Both maps show good agreement in spatial patterns in this region with very diverse fog formation mechanisms. It is found that fog/low cloud layers display distinct spatial differences in terms of geometrical thickness and detection accuracy. The number of fog/low cloud instances missed by passive-sensor retrievals due to multi-layer cloud situations is considerable, with clear regional differences.
Lidar Studies of Wind Turbulence in the Stable Atmospheric Boundary Layer
Authors: Banakh Viktor A. , Smalikho Igor N.
Published: August 2018

The kinetic energy of turbulence, the dissipation rate of turbulent energy, and the integral scale of turbulence in the stable atmospheric boundary layer at the location heights of low-level jets (LLJs) have been measured with a coherent Doppler light detection and ranging (lidar) system. The turbulence is shown to be weak in the central part of LLJs. The kinetic energy of turbulence at the maximum velocity heights of the jet does not exceed 0.1 (m/s)2, while the dissipation rate is about 10−5 m2/s3. On average, the integral scale of turbulence in the central part of the jet is about 100 m, which is two to three times less than the effective vertical size of the LLJ.
Learning to See the Vibration: A Neural Network for Vibration Frequency Prediction
Authors: Liu Jiantao , Yang Xiaoxiang
Published: August 2018

Vibration measurement serves as the basis for various engineering practices such as natural frequency or resonant frequency estimation. As image acquisition devices become cheaper and faster, vibration measurement and frequency estimation through image sequence analysis continue to receive increasing attention. In the conventional photogrammetry and optical methods of frequency measurement, vibration signals are first extracted before implementing the vibration frequency analysis algorithm. In this work, we demonstrate that frequency prediction can be achieved using a single feed-forward convolutional neural network. The proposed method is verified using a vibration signal generator and excitation system, and the result compared with that of an industrial contact vibrometer in a real application. Our experimental results demonstrate that the proposed method can achieve acceptable prediction accuracy even in unfavorable field conditions.
Systemic Design Approach to a Real-Time Healthcare Monitoring System: Reducing Unplanned Hospital Readmissions †
Authors: Alkhaldi Faisal , Alouani Ali
Published: August 2018

Following hospital discharge, millions of patients continue to recover outside formal healthcare organizations (HCOs) in designated transitional care periods (TCPs). Unplanned hospital readmissions of patients during TCPs adversely affects the quality and cost of care. In order to reduce the rates of unplanned hospital readmissions, we propose a real-time patient-centric system, built around applications, to assist discharged patients in remaining at home or in the workplace while being supported by care providers. Discrete-event system modeling techniques and supervisory control theory play fundamental roles in the system’s design. Simulation results and analysis show that the proposed system can be effective in documenting a patient’s condition and health-related behaviors. Most importantly, the system tackles the problem of unplanned hospital readmissions by supporting discharged patients at a lower cost via home/workplace monitoring without sacrificing the quality of care.
Recording Heart Rate Variability of Dairy Cows to the Cloud—Why Smartphones Provide Smart Solutions
Authors: Wierig Maren , Mandtler Leonard P. , Rottmann Peter , Stroh Viktor , Müller Ute , Büscher Wolfgang , Plümer Lutz
Published: August 2018

In the last decades, there has been an increasing interest in animal protection and welfare issues. Heart rate variability (HRV) measurement with portable heart rate monitors on cows has established itself as a suitable method for assessing physiological states. However, more forward-looking technologies, already successfully applied to evaluate HRV data, are pushing the market. This study examines the validity and usability of collecting HRV data by exchanging the Polar watch V800 as a receiving unit of the data compared to a custom smartphone application on cows. Therefore, both receivers tap one signal sent by the Polar H7 transmitter simultaneously. Furthermore, there is a lack of suitable methods for the preparation and calculation of HRV parameters, especially for livestock. A method is presented for calculating more robust time domain HRV parameters via median formation. The comparisons of the respective simultaneous recordings were conducted after artifact correction for time domain HRV parameters. High correlations (r = 0.82–0.98) for cows as well as for control data set in human being (r = 0.98–0.99) were found. The utilization of smart devices and the robust method to determine time domain HRV parameters may be suitable to generate valid HRV data on cows in field-based settings.
Event-Based Communication and Finite-Time Consensus Control of Mobile Sensor Networks for Environmental Monitoring
Authors: Hu Yu , Lu Qiang , Hu Yanzhu
Published: August 2018

This paper deals with the problem of environmental monitoring by designing a cooperative control scheme for mobile sensor networks. The proposed cooperative control scheme includes three main modules: a wireless communication module, a direction decision module, and a motion control module. In the wireless communication module, an event-based communication rule is proposed, which means that mobile sensor nodes do not send their positions, velocities, and the data of environmental attributes to the other sensor nodes in real-time for the coordination and control of mobile sensor networks. Due to using the event-based communication rule, the communication bandwidth can be saved. In the direction decision module, a radial basis function network is used to model the monitored environment and is updated in terms of the sampled environmental data and the environmental data from the other sensor nodes by the wireless communication module. The updated environment model is used to guide the mobile sensor network to move towards the region of interest in order to efficiently model the distribution map of environmental attributes, such as temperature, salinity, and pH values for the monitored environment. In the motion control module, a finite-time consensus control approach is proposed to enable the sensor nodes to quickly change their movement directions in light of the gradient information from the environment model. As a result of using the event-based communication rule in the wireless communication module, the proposed control approach can also lower the updating times of the control signal. In particular, the proposed cooperative control scheme is still efficient under the directed wireless communication situation. Finally, the effectiveness of the proposed cooperative control scheme is illustrated for the problem of environmental monitoring.
Remote Cell Growth Sensing Using Self-Sustained Bio-Oscillations
Authors: Pérez Pablo , Huertas Gloria , Olmo Alberto , Maldonado-Jacobi Andrés , Serrano Juan A. , Martín María E. , Daza Paula , Yúfera Alberto
Published: August 2018

A smart sensor system for cell culture real-time supervision is proposed, allowing for a significant reduction in human effort applied to this type of assay. The approach converts the cell culture under test into a suitable “biological” oscillator. The system enables the remote acquisition and management of the “biological” oscillation signals through a secure web interface. The indirectly observed biological properties are cell growth and cell number, which are straightforwardly related to the measured bio-oscillation signal parameters, i.e., frequency and amplitude. The sensor extracts the information without complex circuitry for acquisition and measurement, taking advantage of the microcontroller features. A discrete prototype for sensing and remote monitoring is presented along with the experimental results obtained from the performed measurements, achieving the expected performance and outcomes.
Media and Generations in Portugal
Authors: Vieira Jorge
Published: August 2018

Many discourses link media with generations, ascribing particular appetence for the use of new media to youth, in contrast with older generations. This article aims to give an account of the empirical regularities but also differences found in a longitudinal quantitative analysis of Internet users, uses, and media preferences among different Portuguese age cohorts. Making use of questionnaire surveys with representative samples, the importance of generational belongings in structuring different types of relationships with media is demonstrated, as youngsters seem to prefer new media. However, this variable does not hold in itself complete explanatory power. The importance of formal education, besides other sociographic variables, is clear, indicating the existence of social disparities within age cohorts, with repercussions on the mediated access to resources and opportunities. The diversity and inequalities found through the statistical analysis help to combat the rhetoric of a supposedly innate, all-encompassing digital nativity. By adopting a social constructivist approach, with a more holistic scope, this article also aims to reconstruct part of the complexity and multidimensionality of the relationship between and within Portuguese generations with media, thereby deconstructing more essentialist and homogenising notions of youth and generations.
The Remains of the Socialist Legacy: The Influence of Socialist Socialization on Attitudes toward Income Inequality
Authors: Ignácz Zsófia S.
Published: August 2018

Despite convergence processes between Western and post-socialist societies in the past three decades, there are still considerable cross-country differences in individuals’ attitudes toward income inequality. To explain these differences, studies have primarily focused on the role of macro level differences and have only theoretically acknowledged how the role of diverging socialization experiences could also be responsible. To date, little is known about the importance of socialization for attitudes toward income inequality. This article assesses whether the differences between Western and post-socialist countries are influenced by socialization effects. Applying an adapted age-period-cohort analysis on the dataset of the International Social Survey Program’s (ISSP) “Social Inequality” module in survey years 1992, 1999, and 2009, the paper shows that socialization has a substantial effect on attitudes and a socialist socialization clearly differentiates individuals from post-socialist countries from Westerners. Results underline that experiences gained in formative years are crucial for attitudes. A further finding is that both perception and preferences toward income inequality are influenced by socialization.
The Impact of Facebookers’ Posts on Other Users’ Attitudes According to Their Age and Gender: Evidence from Al Ain University of Science and Technology
Authors: Altakhaineh Abdel Rahman Mitib , Alnamer Sulafah Abdul Salam
Published: August 2018

This study aims at exploring the reasons that drive many Facebookers to share negative posts on Facebook, with a special focus on their gender and age. It also aims at identifying the negative attitudes and feelings that negative Facebook posts might evoke in Facebookers. Thus, a mixed-methods approach was adopted employing both a five-point agreement Likert scale questionnaire and semi-structured interviews which were conducted with 40 participants. Based on the participants’ responses, the results show that many Facebookers write posts to satisfy different needs including receiving compliments and attention, sharing daily updates, showing off, and deliberately teasing others, all of which have been found to trigger feelings of jealousy, hatred, annoyance, demotivation, inferiority, and sadness. The study concludes with recommendations for further research.
Daylighting and Energy Performance Evaluation of an Egg-Crate Device for Hospital Building Retrofitting in a Mediterranean Climate
Authors: Calama-González Carmen María , León-Rodríguez Ángel Luis , Suárez Rafael
Published: August 2018

Hospital buildings present a significant savings potential in order to meet the objectives of H2020. The improvement of healthcare built environments contributes to improving the health of patients. In this respect, passive measurements must be prioritized, especially in relation to the weakest element of the building thermal enclosure: the window opening. Shading devices allow solar radiation and indoor temperature to be controlled, as well as improving visual comfort, mostly in buildings with a Mediterranean climate. This factor is of great importance when considering the increase in outdoor temperatures expected due to climate change. Unlike other studies in which predictive models are implemented, this paper examines a methodology based on the simultaneous monitoring of ambient variables, in real use and operative conditions, for two hospital rooms located in southern Spain. The aim of this research is to provide a comparative assessment of ambient conditions in a standard room with an egg-crate device and in a non-shaded one. The use of an egg-crate device allows a better yearly performance, improving natural illuminance levels, reducing incident solar radiation on the window, and decreasing artificial lighting consumption. However, its efficiency is greatly conditioned by the user patterns in relation to ambient systems, as the blind aperture level and the activation of the lighting system are directly controlled by users.
University Contributions to the Circular Economy: Professing the Hidden Curriculum
Authors: Nunes Ben Tirone , Pollard Simon J. T. , Burgess Paul J. , Ellis Gareth , De los Rios Irel Carolina , Charnley Fiona
Published: August 2018

In a world dominated by linear economic systems, the road to improving resource use is multi-faceted. Whilst public and private organisations are making progress in introducing sustainable practices, we ask ourselves the extent to which education providers are contributing to the circular economy. As engines for skills and knowledge, universities play a primary role in propelling circular economy approaches into reality and, as such, hold the potential for raising the bar on sustainable performance. A rapid evidence assessment (REA) was therefore undertaken to examine the interactions between university estate management and the circular economy. This assessment identified six pertinent themes: campus sustainability, the hidden curriculum, environmental governance, local impact, university material flows, and the role of universities as catalysts for business and examined 70 publications. A second part of the study reviewed the environmental activities of 50 universities ranked highly in terms of their environmental credentials or their environmental science courses. The results are presented and then discussed in terms of how universities can affect material flows, promote sustainability outside of the formal curriculum, and act as catalysts with business. The economic significance of universities provides an appreciable demand for circular products and services. Universities should develop “hidden curriculum” plans to promote improved environmental behaviours of staff and students. Universities can also catalyse a circular economy by working with business to improve eco-effectiveness as well as eco-efficiency. For example, projects should extend the focus from decreasing carbon footprint to achieving carbon positivity, from improving water efficiency to treating wastewater, and from recycling to reverse logistics for repurposing. Pilot projects arising from such work could provide valuable research bases and consultancy opportunities.
Local Agroforestry Practices for Food and Nutrition Security of Smallholder Farm Households in Southwestern Ethiopia
Authors: Jemal Omarsherif , Callo-Concha Daniel , Van Noordwijk Meine
Published: August 2018

Food and nutrition security (FNS) rests on five pillars: availability, access, utilization, stability, and sovereignty. We assessed the potentials of local agroforestry practices (AFPs) for enabling FNS for smallholders in the Yayu Biosphere Reserve (southwestern Ethiopia). Data was collected from 300 households in a stratified random sampling scheme through semi-structured interviews and farm inventory. Utility, edibility, and marketability value were the key parameters used to determine the potential of plants in the AFPs. Descriptive statistics, ANOVA, and correlation analysis were employed to determine the form, variation, and association of local AFP attributes. Homegarden, multistorey-coffee-system, and multipurpose-trees-on-farmlands are the predominant AFPs in Yayu. Multipurpose-trees-on-farmlands are used mainly for food production, multistorey-coffee-system for income-generation, and homegarden for both. The 127 useful plant species identified represent 10 major plant utility groups, with seven (food, fodder, fuel, coffee-shade, timber, non-timber-forest-products, and medicinal uses) found in all three AFPs. In total, 80 edible species were identified across all AFPs, with 55 being primarily cultivated for household food supply. Generally, household income emanates from four major sources, multistorey-coffee-system (60%), homegarden (18%), multipurpose-trees-on-farmlands (13%), and off-farm activities (11%). Given this variation in form, purpose, and extracted benefits, existing AFPs in Yayu support the FNS of smallholders in multiple ways.