bluuebunny/crossref_metadata_2025 huggingface dataset:
Peculiarities of Psychoemotical Stability of Oncological Patients at Different Stages of Treatment
Authors: Абакарова Э.Г. , Хурцев К.В.
Published: March 2022

Психогенные реакции онкологических пациентов отличаются разнообразием, степенью выраженности и специфичностью в зависимости от этапа терапии. В работе выдвинута гипотеза о том, что степень эмоциональной устойчивости и реагирования пациентов, получающих химиотерапию, будет отличаться от таковой у онкопациентов других отделений.Результаты исследования показывают, что физический и психоэмоциональный страх перед процедурой химиотерапии формирует у данных пациентов повышенную личностную и ситуативную тревожность, которые могут быть пусковым механизмом в формировании эпигастрального синдрома и большого количества желудочных жалоб. Дополнительные места локализации болей у онкопациентов позволяет обнаружить проективный тест «Птица». Уровень психоэмоциональной устойчивости пациентов химиотерапевтического отделения достоверно ниже, чем у онкопациентов хирургического отделения, что определяет необходимость формирования программ психологического сопровождения онкопациентов для разных отделений.

The previously obtained data indicate that in cancer patients, at all stages of treatment, there are certain psychogenic reactions that differ in their clinical manifestations and severity. In this study, it is assumed that the degree of psychoemotional response and resistance in patients on chemotherapeutic treatment will differ from those of other departments.The results of the research show that physical and psychoemotional fear of the chemotherapy procedure form the increased personal and situational anxiety in these patients, which can be a trigger mechanism in the formation of epigastric syndrome and a large number of gastric complaints. The projective test “Bird” lets to detect additional places of pain localization in cancer patients. The level of psychoemotional resistance of chemotherapy patients is significantly lower than in oncological surgical departments, which determines the need for the formation of psychological support programs for cancer patients of different departments.
The Psychological Patterns of Emotional Intelligence Development in Adolescence as a Condition of Personal Mental Health
Authors: Игнатович E.М. , Лящ О.П.
Published: March 2022

Актуальность этого исследования обусловлена необходимостью решения вопроса развития эмоционального интеллекта молодого поколения и потребностями психолого-медицинской практики в противодействии негативным последствиям, связанным с невротическими расстройствами, поскольку последние являются важным фактором риска для психического здоровья личности. В нашем исследовании было обнаружено, что у молодых людей с депрессиями и тревожно-фобическими расстройствами уровень эмоционального интеллекта ниже, чем у психически здоровых представителей категории юношеского возраста, что проявилось в слабо развитой способности первых сознательно регулировать эмоции. При этом характер взаимосвязей между психофизиологическими факторами и способностями психически здоровой личности юношеского возраста к идентификации, использованию, пониманию, сознательной регуляции эмоций выражается в том, что средний и высокий уровни аффективнокогнитивного, поведенчески-деятельностного и мотивационно-рефлексивного компонентов эмоционального интеллекта показали те испытуемые, которые имели выраженный уровень силы и подвижности нервной системы, а также способность к саморегуляции аффективнокогнитивных функций и состояний.

The actuality of the research is specified by the necessity of resolving the issue of development of emotional intelligence in young generation and the need of psychological and medical practice in countering the negative consequences associated with neurotic disorders, because the last ones arean important risk factor for the individual mental health. The study shows that young people with depression and anxiety-phobic disorders have lower level of emotional intelligence than mentally healthy representatives of the youth category, which was manifested in the poorly developed ability of the former to consciously regulate emotions. Moreover, the specificity of interrelation between psychophysiological factors and the ability of a mentally healthy young person to identify, use, understand, consciously regulate their emotions is expressed in the fact that the average and high levels of affective and cognitive, behavioral, motivational and reflective components of emotional intelligence were shown by those subjects, who had a pronounced level of strength and mobility of the nervous system, as well as the ability to self-regulate the affective and cognitive functions and conditions.
Acute Issues of Pharmacotherapy of Coronavirus Infection. Position of a Clinical Pharmacologists
Authors: Гавриленко Л.Н. , Кожанова И.Н. , Романова И.С. , Садовская О.Г.
Published: March 2022

COVID-19 (от англ. COronaVIrus Disease 2019) – новая коронавирусная болезнь 2019 года – заболевание, вызванное новым коронавирусом SARS-CoV-2, впервые выявленное в городе Ухань, провинция Хубэй, Китай. Вирусопосредованное повреждение многих органов, главным образом дыхательных путей, активация иммунного ответа с высвобождением провоспалительных цитокинов, а также гиперактивация каскада свертывания и агрегации тромбоцитов, приводящая к микро- и макрососудистому тромбозу, являются основными патологическими признаками COVID-19.В статье представлены клинико-фармакологические особенности основных лекарственных средств, применяемых для лечения пациентов с коронавирусной инфекцией, критическая оценка современных данных об «этиотропных» препаратах, противовоспалительных средствах, антитромботических препаратах. Особое внимание уделено оценке эффективности и безопасности их применения, предупреждению нежелательных эффектов.

COVID-19 (from the English COronaVIrus Disease 2019) – new Coronavirus disease 2019 – a disease caused by the new coronavirus SARS-CoV-2, first identified in Wuhan, Hubei province, China.Virus-mediated damage to many organs, mainly the respiratory tract, activation of the immune response with the release of Pro-inflammatory cytokines, as well as hyperactivation of the platelet coagulation and aggregation cascade, leading to micro-and macrovascular thrombosis, are the main pathological signs of COVID-19.The article presents the clinical and pharmacological features of the main medicines used for the treatment of patients with coronavirus infection. critical evaluation of current data on "etiotropic" drugs, anti-inflammatory drugs, antithrombotic drugs. Special attention is paid to evaluating the effectiveness and safety of their use, preventing undesirable effects.
Clinical Aspects of Local Application of Ultralow Temperatures as a Method of Ablation of Liver and Pancreatic Malignancies (Literature Review)
Authors: Козачук Е.С. , Щигель И.А. , Стрилец Е.А.
Published: March 2022

Сверхнизкие температуры в качестве локального метода абляции злокачественных ново- образований успешно применяются во многих мировых клиниках в течение нескольких де- сятилетий. Данный метод получил название криогенной абляции, или криоабляции. Преиму- щества криогенной абляции: деструкция заданного объема патологического очага с четкой демаркацией зоны некроза и ее биологической инертностью, гемостаз, отсутствие выражен- ного болевого синдрома, безопасность применения в непосредственной близости к крупным кровеносным сосудам, противоопухолевая иммуностимуляция, возможность комбинирован- ного применения с другими методами лечения, активная регенерация без формирования гру- бых рубцов, многократность циклов, простота в применении. Основным показанием к локаль- ному применению сверхнизких температур при лечении злокачественных новообразований печени является циторедукция опухолевых очагов с целью локального контроля опухолевого роста, уменьшения стадии онкопроцесса, конверсии в резектабельное состояние и, как след- ствие, улучшения отдаленных результатов лечения пациентов, которые на момент обращения за специализированной медицинской помощью не подлежат радикальному хирургическому лечению.

Ultra-low temperatures, as a local method of malignant neoplasms ablation, have been successfully used in many clinics worldwide for several decades. This method is called cryogenic ablation or cryoablation. The advantages of cryogenic ablation are the following: destruction of appropriate volume of the pathological focus with the demarcation of the necrosis zone and its biologicalinertness, hemostasis, absence of pronounced pain syndrome, safety of use closely to large blood vessels, anti-tumor immunostimulation, possibility of combined use with other methods of treatment, active regeneration without formation of rough scars, multiple cycles, easy to use. The main indication for local application of ultra-low temperatures in treatment of malignant hepatic and pancreatic neoplasms is cytoreduction of tumor foci for local tumor control, reduction of the stage of the oncological process, conversion to resectable state, and, as a consequence, improvement of the 5-year survival of patients, who have contraindications for radical surgical treatment at time of medical care request.
Clinic, Diagnosis and Treatment of Primary Hyperaldosteronism in Children: Literature Review and Clinical Case
Authors: Волк Ю.В. , Солнцева А.В. , Шлимакова Е.И. , Сукало А.В.
Published: March 2022

Первичный гиперальдостеронизм (ПГА) – заболевание, развивающееся в результате избыточной продукции альдостерона клубочковой зоной коры надпочечников, полностью или частично автономной по отношению к ренин-ангиотензиновой системе. ПГА выявляют у 1% пациентов с эссенциальной гипертензией. ПГА в детском возрасте встречается крайне редко и требует исключения заболеваний, имеющих сходную клиническую картину, что значительно усложняет диагностику ПГА. К группам риска по развитию ПГА относятся пациенты с артериальной гипертензией (АГ) и гипокалиемией; пациенты с АГ и мышечными судорогами, слабостью, нарушением концентрационной функции почек; пациенты с семейным анамнезом АГ; пациенты с отсутствием эффекта от применения традиционной гипертензивной терапии. Анализ клинических проявлений заболевания, гормональных показателей крови, проведение компьютерной диагностики позволяют выявлять ПГА на ранних стадиях, что является залогом успешного лечения заболевания. В статье представлен обзор литературы по диагностическому поиску при подозрении на ПГА, а также описание клинического случая ПГА у девочки 9 лет с гипокалиемией и АГ, рефрактерной к проводимой терапии.

Primary hyperaldosteronism (PHA) is the disease that develops as a result of excessive aldosterone production by the glomerular zone of the adrenal cortex, which is fully or partially autonomous with respect to the renin-angiotensin system. PHA is detected in 1% of patients with essential hypertension. PHA in children is extremely rare and requires the exclusion of diseases that have a similar clinical picture, which greatly complicates the diagnosis of PHA. The risk groups for the development of PHA include patients with arterial hypertension (AH) and hypokalemia; patients with АН and muscle cramps, weakness, impaired concentration function of the kidneys; patients with a family history of АН; patients with no effect from the use of traditional hypertensive therapy. Analysis of clinical manifestations of the disease, hormonal indices, and computer diagnostics let todetect PHA in the early stages, which is the key to successful treatment of the disease. The article provides a review of the literature on diagnostic search for suspected PHA, as well as the description of the clinical case of PHA in a 9-year-old girl with hypokalemia and АН refractory to the therapy.
DAMPAK PANDEMIK COVID 19 TERHADAP TINGKAT PENGEMBALIAN PINJAMAN KOPERASI DI KABUPATEN SUMBA TIMUR
Authors: Rewa Karolina A
Published: March 2022

Penelitian ini bertujuan untuk mengetahui dampak pandemik COVID 19 terhadap tingkat pengembalian pinjaman koperasi di Kabupaten Sumba Timur. Penelitian ini menggunakan metode penelitian deskriptif kualitatif . Melalui tehnik ini, akan digambarkan seluruh data atau fakta yang diperoleh tentang dampak pandemik Covid 19 terhadap tingkat pengembalian pinjaman koperasi di Kabupaten Sumba Timur. Hasil penelitian ini menunjukkan bahwa sebesar 77 persen Koperasi di Kabupaten Sumba Timur mengalami dampak buruk akibat wabah COVID 19 dengan tingkat pengembalian pinjaman koperasi dengan kategori kurang lancar sebesar 59 persen dan tingkat pengembalian pinjaman dengan kategori macet sebesar 18 persen. Sedangkan berdasarkan dampak Pandemik COVID 19 secara umum terhadap tingkat pengembalian pinjaman koperasi di Kabupaten Sumba Timur mengalami kondisi tingkat pendapatan menurun sebesar 76,5 persen dan mengalami kemacetan usaha sebesar 5,88 persen.
Estudio de la variabilidad genética de Brucella melitensis en el noroeste de la provincia de San Luis
Authors:   , Arregui Matías Ezequiel
Published: March 2022

Los objetivos del presente trabajo fueron emplear técnicas de genotipificación molecular en un escenario real, describir genotipos circulantes de Brucella melitensis en el noroeste de la provincia de San Luis y poner a prueba la capacidad de discriminación de las técnicas. Con este propósito se identificaron rodeos con diferentes valores de prevalencia de brucelosis mediante técnicas serológicas. A partir de su identificación se procesaron tejidos caprinos y ovinos para obtener aislamientos en pureza de B. melitensis y a su vez, mediante diferentes métodos de extracción de ADN y PCR se evidenció la presencia del patógeno en tejidos. La genotipificación utilizó el ADN proveniente de aislamientos y ADN total de tejidos de animales infectados, sobre los cuales se identificó previamente ADN bacteriano de B. melitensis. Se empleó el esquema MLVA 16, que utiliza la variabilidad de 16 marcadores moleculares para generar una individualización inequívoca de los genomas de B. melitensis provenientes de distintos animales. Los genotipos se analizaron para determinar la relación filogenética entre ellos y se sumaron los datos de georreferenciación de los mismo para tener una información completa sobre la presencia y circulación de distintos genotipos en cada departamento. Este estudio permitió identificar 59 genotipos circulante en los departamentos productores caprinos de la provincia de San Luis. Inclusive el modelo de relación filogenética encontró algunos de los genotipos descriptos como potenciales candidatos a fundadores del linaje que se encuentra distribuido en diferentes áreas de la provincia. Se confirmó la capacidad discriminatoria de la técnica en una situación epidemiológica real, inclusive discriminando genotipos dentro de un mismo rodeo, aun trabajando con ADN proveniente tanto de aislamientos como de ADN total de tejidos proveniente de animales infectados.
Pengembangan Instrumen Penilaian Sikap, Pengetahuan, dan Keterampilan dalam Pendidikan Jasmani
Authors: Mustafa Pinton Setya , Masgumelar Ndaru Kukuh
Published: March 2022

Penilaian adalah pengumpulan informasi dari hasil belajar peserta didik. Secara umum penilaian hasil belajar dibagi menjadi tiga aspek, yaitu: sikap, pengetahuan, dan keterampilan. Instrumen penilaian yang digunakan guru sangat beragam sesuai kondisi lapangan yang dirasakan oleh guru tersebut. Tujuan dari artikel ini adalah membahas tentang pengembangan penilaian sikap, pengetahuan, dan keterampilan dalam pendidikan jasmani. Penelitian ini menggunakan pendekatan kajian kepustakaan, dengan analisis data melalui pendekatan kualitatif menggunakan reduksi data, penyajian data, dan penarikan kesimpulan.  Penilaian sikap adalah nilai dari budi pekerti peserta didik baik secara individu maupun sosial selama mengikuti pelajaran di sekolah. Penilaian Pengetahuan merupakan hasil nilai kompetensi peserta didik dalam menggunakan akal pikiran mereka dalam menyerap materi yang diajarkan oleh guru. Penilaian keterampilan didefinisikan nilai yang diperoleh dari unjuk kerja, baik berbasis proses maupun produk, dalam pendidikan jasmani biasanya hasil kemampuan gerakan olahraga. Dalam mengembangkan instrumen penilaian dalam pembelajaran, syarat utamanya minimal adalah valid, reliabel, dan objektif. Dengan instrumen yang baik, maka nilai yang diperoleh peserta didik mencerminkan kemampuan mereka yang sesungguhnya, sehingga mudah untuk memberikan tindak lanjut maupun umpan baik setelah pembelajaran.
Ensuring Safety of Forensic Medical Examiners during Autopsy of Suspected or Detected Cases of Deadly Communicable Diseases
Authors: Ilina OA , Milushkina OYu , Timerzyanov MI , Shulaev AV
Published: March 2022

Background: Forensic medical examiners are known to be exposed to a combined effect of occupational risk factors potentially leading to adverse health outcomes. In the current epidemiologic situation largely influenced by the ongoing COVID-19 pandemic, postmortem examination of the bodies having signs of deadly communicable diseases, including the novel coronavirus disease, poses a high infection risk, thus making the development and implementation of appropriate preventive measures an urgent and important task.
Objective: To summarize and systematize the results of scientific research and requirements of legal and regulatory documents in the field of ensuring workplace safety of forensic medical examiners.
Materials and methods: We searched for literary sources published in Russian and English in 2000–2021 in the PubMed, eLibrary, and Cyberleninka databases using such keywords as “healthcare workers”, “safety”, “forensic medical examiner”,
“prosector”, and “deadly infections”. We conducted an analytical review of legal documents regulating safety in the conduct of forensic medical examination. Based on the relevance of search results, we selected 30 articles and five legal and regulatory
documents for this review and carried out their content analysis using descriptive and analytical methods.
Results: As a solution to the problem of epidemiological surveillance, a series of modular buildings for postmortem examination of patients with suspected or confirmed deadly infectious diseases, including COVID-19, was developed and introduced.
Conclusions: Our findings indicate that in the context of the current pandemic, it is critical to update the requirements for biological safety of forensic experts stipulated in sanitary rules and norms. Construction of modular special purpose buildings
in the city of Kazan contributed to improvement of biological safety during autopsy of COVID-19 victims.
A Daseinsanalyse de Medard Boss nos periódicos científicos brasileiros
Authors: Carvalho Gabriel Henrique de Souza , Evangelista Paulo Eduardo Rodrigues Alves
Published: March 2022

Medard Boss é considerado fundador da Daseinsanalyse. Conquanto a relevância de seu legado para a psicologia, sua obra é pouco conhecida na comunidade científica brasileira. Esta pesquisa, no intento de descobrir o que e como se tem referenciado o daseinsanalista, orienta-se por uma revisão integrativa da literatura de artigos científicos, indexados em portais abertos e gratuitos, que citem Medard Boss. Foram eleitas palavras-chave, então aplicadas em três bancos de dados (SciELO, PePSIC e Lilacs). Após seleção por critérios de exclusão, chegou-se a um N final de 37 publicações. Dos resultados, percebe-se que Boss é pouco referenciado pelos artigos brasileiros. Quando lembrado, a maior parte das menções é breve. Uma minoria de autores concentra a maior parte das publicações. Apenas dois livros de Boss estão traduzidos para o português. Vinte e sete porcento dos artigos que remetem ao daseinsanalista não usam nenhuma referência de sua obra.
Pertumbuhan dan kelangsungan hidup ikan nila Oreochromis niloticus yang dikultur pada sistem akuaponik dengan kepadatan biofilter kangkung yang berbeda
Authors: Gerung Pramulya R.A , Mudeng Joppy D. , Salindeho Indra R.N. , Longdong Sammy N.J. , Pangkey Henneke , Rumengan Inneke F.M.
Published: March 2022

This research was conducted to determine the optimal density of kale plants as biofilter in an aquaponic system that can trigger the highest growth and survival of tilapia. The experiment was designed in a completely randomized design (CRD) with 3 treatments and 3 replications so that there were 9 experimental units. The factor tested was the different density of kale plants as biofilter in the aquaponics system, where treatment A: 6 kale plants/0,24m2, B: 12 kale plants/0,24m2, and  K: without kale plants (as control). This study was conducted for 28 days.  Collected data  included weight, length and number of fish, which were then converted to  absolute growth rate (weight and length) , daily growth rate, survival rate and kale plant growth. Data  were analyzed using ANOVA  and then Least Significance Differences (LSD) for  further analysis.   The results  showed that the different density of  kale plants had no significant effect on absolute growth rate (weight and  length)  and daily growth rate, but had a significant effect on the survival rate of fish. The LSD results  showed that density of 6 kale plants/0,24m2 (A) were not significantly different from that of 12 individuals kale plants/0,24m2 (B), but both treatments were significantly different from the control (K).  The range of ammonia  was between 0.29 – 0.91 mg/l, nitrite 0.55 – 1.06 mg/l, and nitrate 10 - 47 mg/l.
Biodiversitas ikan Amfidromus Gobiidae di Perairan Indonesia
Authors: Salindeho Indra R. N.
Published: March 2022

Gobiidae fish are distributed widely in tropical and subtropical waters, and inhabit almost all benthic habitats ranging from freshwater, intertidal to offshore, with varied substrates such as muddy bottom, rocky, and coral beds.  The diets of Gobiidae varies greatly, from microalgae to small fish. The life cycle follows the amphidromus migration pattern, the mature Gobiidae spawn in fresh water and the hatched larvae drift to brackish waters or to the sea, and will return to fresh water in a few weeks or months later.  Species of Gobiidae varies greatly in Indonesian waters. The species composition of Gobiid fish schooling varies greatly by location and by seasonal appearance  in estuary waters.
Penerapan Algoritma C4.5 Pada Imbalanced Dataset Untuk Memprediksi Kegagalan Angsuran Properti
Authors: Susanto Yodi , Setiono Devit , Syafrullah Muhammad
Published: March 2022

In this research, the data collection carried out by studying the patterns of consumers who fail to pay, which aimed to build a model so that it could be used in predicting customers who have the potential to fail to pay. The research used the Cross-Industry Standard Process for Data Mining (CRISP-DM) method with details of the business understanding process, data understanding, data preparation, modeling, evaluation and deployment / interpretation. The dataset in this research was taken from sales, cancellation and consumer data from January 2016 to December 2019. Because the dataset in this research was an imbalanced dataset, the researchers tried to use Synthetic Minority Oversampling Technique (SMOTE) in handling the imbalanced dataset. The research conducted a comparison of the value of accuracy, precision, recall, f measure and Area Under the ROC Curve (AUC) between the original dataset and the dataset for the addition of the SMOTE technique to several algorithms including C4.5, K-NN and Naïve Bayes. The attributes used in this research were source of funds, purpose of purchase, age, selling price, occupation, total installments, percentage of total installments, monthly installments, percentage of late installments and status. From the comparison, it was found that the C4.5 algorithm with the SMOTE 480% dataset had the highest accuracy value of 97.62%, precision of 0.976, recall of 0.976, f measure of 0.976 and AUC of 0.986 which meant Excellent Classification. From the research conducted, it was expected that the model formed on the imbalanced dataset with the C4.5 and SMOTE algorithms could be used to predict consumer installment failures.
Pengembangan E-Commerce Menggunakan Metode Business Model Canvas (BMC) Pada Toko Amira Bucket
Authors: Samsinar Samsinar , Permatasari Nada
Published: March 2022

Covid-19 telah mengubah tren ekonomi global. E-Commerce telah berkembang pesat dalam beberapa tahun terakhir dan menjadi semakin intens karena pandemi Covid-19. Toko Amira Bucket adalah sebuah toko yang menjual berbagai macam buket, Seiring berkembangnya waktu pemilik toko ingin meningkatkan penjualannya tapi terbatas pada media yang bisa dimanfaatkan untuk mempromosikan buket dan melayani para pelanggannya. Media sosial yang saat ini dimanfaatkan untuk mempromosikan buket sekaligus melayani para pelanggan yang memesan secara daring kurang efektif karena sering terjadinya penumpukan chat dari para pelanggan yang hanya ingin bertanya mengenai produk ataupun para pelanggan yang mengirimkan bukti pembayaran kepada pemilik sehingga pemilik toko sering kesulitan dalam mencari bukti pembayaran dari para pelanggannya. Oleh karana itu dibutuhkan sebuah sistem e-commerce sebagai solusi atas permasalahan yang ada, dan dengan menerapkan Business Model Canvas untuk menganalisis model bisnis Toko Amira Bucket sehingga dapat menghasilkan kinerja yang lebih maksimal. Dengan adanya sistem e-commerce pada Toko Amira Bucket ini dapat menjadi sarana untuk memasarkan produk yang ditawarkan menjadi lebih luas dengan menggunakan fitur Search Engine Optimizitation.
Pencarian Stasiun Kereta Terdekat dengan Algoritma A Star Berbasis Android di Bekasi
Authors: Dwikurniawan Ikhsan , Herlawati Herlawati , Suraji Robertus
Published: March 2022

Transportation has become one of the most important needs in daily activities in social life. Advances in information technology that exist today, can be used as a means to improve public services, one of which is in the railway sector. With advances in information technology can make it easier for people to find information quickly and easily. There are several obstacles, namely the lack of information about the nearest station route. This study aims to create an android-based nearest station search application with the shortest route to the destination station using the A STAR Algorithm. The A STAR algorithm is an algorithm that looks for the shortest route to reach the expected destination. In this study Kranji Station, Bekasi Station, East Bekasi Station, Tambun Station, Cibitung Station, Telaga Murni Station, Cikarang Station. With tests carried out from 7 times of testing, it can be ensured that 4 times the A STAR algorithm is successful in the shortest distance, 1 time the results of the A STAR algorithm are the same as Google Maps, and 2 times the A-Star algorithm shows a longer distance than Google Maps.
ACTIVITY ETHANOL EXTRACT OF MANGGA (Curcuma mangga Val.) FEET UDEM RAT WHITE
Authors: Salman Salman , Indriana Meutia
Published: March 2022

The rhizome of mango Curcuma is empirically used as a traditional medicine for the treatment of gastric pain, pain, and inflammation due to hemorrhoids, sore throat, bronchitis, and asthma. The aim of this study was to determine the chemical compound content of secondary metabolites and the activity of the ethanol extract of Temu Mango (Curcuma mangga Val.) on the reduction of carrageenan-induced rat paw edema. The results of a preliminary examination of the chemical content of the rhizome of Intersection mango (Curcuma mango Val.) showed the presence of glycosides, flavonoids, saponins, essential oils, and steroids. In general, the suspension of the ethanol extract of Temu Mango at doses of 50, 100, 200 mg/kg BW gave an anti-inflammatory effect that began to appear in the first half-hour and continued to increase with increasing time. An increase of 2 times the dose of the ethanol extract of Temu Mango showed an anti-inflammatory effect that was not significantly different, but with an increased dose of 4 times, it showed a significant difference. Even the ethanol extract of Intersection mango at a dose of 200 mg/kg BW gave almost the same effect as indomethacin.
SKIN EXTRACT OF GRAPE (Vitis vinifera L) AS DYES IN LIPSTICK FORMULATION
Authors: Salman Salman , Indriana Meutia
Published: March 2022

Grapes (Vitis vinifera L.) belong to the family Vitaceae. The color of the fruit varies. There are red, green and purple. The color of this wine contains anthocyanin dyes that can be used as natural dyes to replace synthetic dyes, the colors they contain are pretty intensive, so the researchers aimed to make lipstick formulations using natural dyes from grape skins. The lipstick formulation consisted of Cera alba, lanolin, vaseline alba, cetyl alcohol, oleum ricini, carnauba wax, propylene glycol, titanium dioxide, oleum rosae, butylhydroxytoluene, tween 80, and nipagin, as well as the addition of grape skin extract with a concentration of 15 %, 20%, 25%, 30%, and 35%. Tests on the preparations made include inspection of homogeneity, melting point, lipstick strength, stability test against changes in shape, color, and odor during 30 days of storage at room temperature, smear test, pH examination, and irritation test preference test (Hedonic test). From the research results, grape skin extract can be formulated into lipstick preparations with pink to dark red colors. Lipstick preparations with grape skin extract as a dye are pretty stable, homogeneous, melting point 59°C, have good lipstick strength, pH ranges from 3.7 to 3.9 (close to the pH of the lip skin) are easy to apply with an even color, and do not irritate. Irritation the preparation preferred by 30 panelists was preparation with a concentration of 25%.
Cuerpo, sexualidad , política
Authors: García Castiñeiras Javier
Published: March 2022

The paper discusses the connection between the Oedipus, the social bond, and the effects of the state terror over human sexuality through film examples, with a special focus on Pasolini’s Oedipus Rex and Sergio Blanco’s theatre play Ostia, which serves Blanco as a bridge between the assassination of Pasolini in Ostia and the disappearance of detainees during the dictatorships in the Río de la Plata.
            Pasolini’s Oedipus Rex allows the director to articulate Freud’s ideas in Totem and taboo and an Oedipus experienced with a violent, fascist father; an experience later sublimated in his work. The impact of culture on sexuality and the impact of both on the construction of the social bond are highlighted.
De trans-tornados y de-generados
Authors: Mirza Labraga Natalia
Published: March 2022

The paper intends to reflect on the issue of gender, sexuality and transsexuality. It works over some real clinic consultations and life experiences. It stops at the impact that this issue generates in the current context, in which the medical and surgical treatments make possible to modify the bodies with hormones therapies and multiple surgeries.
The work also tries to draw some lines to think about this from psychoanalytic perspectives, seeking to get away from psychopathological readings and integrating social and cultural aspects of our contemporaneity.
It insists in not to lose the impact on the novelty of gender change, because the transsexuality is presented as a question to the all psychoanalysis, questioning the classic conceptualizations about sexuation, sex difference and castration.
La incidencia de las diferentes vivencias de desamparo en la construcción de la identidad sexual en cinco niños latentes
Authors: Altmann Marina , Rebella Griselda , Cubría Fernanda , Gandolfi Adriana , Pérez Luisa , Bordaberry María , Moreno Pedro
Published: March 2022

This is the third publishing on the role of child sexuality of our Group on Clinical Investigation in Child Psychoanalysis. On this occasion, we have dealt with the pair protection-helplessness, and, setting our investigation in the study of the sole case, we worked on the papers presented by candidates of the Uruguayan Psychoanalytic Association to become Associated Members, adding materials of other psychoanalytic institutions. In our previous publishing, we focused on the cases of three girls and two boys on this topic.
We observed the pair protection-helplessness while reading the cases of these children written by their analysts.
We think that the feelings of helplessness re-signify the primary helplessness, and the presence of the other-analyst who holds and takes care -protects-, is needed to survive.
We try to face some aspects of protection-helplessness in the parents, which express themselves in the children's either sessions or the necessary appointments of analysts with them, in contexts with their peers and relation to anguish and gender and the transformations along the process of analysis.
Diversidades y disidencias sexuales en el campo psicoanalítico
Authors: Clavero Lerena Mauricio
Published: March 2022

A number of perspectives are addressed through intertextuality concerning the so-called trans childhood at an early age as a way of problematizing the theory and psychoanalytic clinic, considering so certain contemporary sexual logics. It tracks some statements of permanence, as well as those which tend to a modification, product of the relationship of both theory and psychoanalytic clinic and social framework. It postulates a possible conceptualization when it comes to trans childhoods, to then discuss a few aspects regarding the relationship between psychoanalysis and both sexual diversities and dissent. An interdisciplinary conversation is engaged as a form of enrichment toward the psychoanalytic view. It is about an exploratory inquiry based on a qualitative content analysis of bibliographical sources and communication with the theme’s key informants. Coexistence of traditional conceptualizations in tension with more modern ones is resulted from this, not being able to stand in an homogeneous position about this reality, fostering a place for interrogation and complexity.
Cuestiones sobre el odio y la destructividad en la metapsicología freudiana
Authors: Menezes Luis Carlos
Published: March 2022

En el lapso de una década, iniciada a mediados de los años noventa, Freud construyó un imponente sistema teórico para dar cuenta del sufrimiento neurótico: las neurosis fueron descriptas en cuadros nosográficos, frutode la observación fina de sus manifestaciones, pero también producto del enorme poder heurístico ofrecido por las concepciones metapsicológicas iniciales. ...
Femicidio, un crimen de odio por exceso de amor
Authors: Peskin Leonardo
Published: March 2022

The paper approaches femicide as part of a series of violent crimes. It is an attempt at describing and understanding the role of the victim and ofthe aggressor in these cases. It characterizes the psychosis of the murderer and the masochism of some victims. It expands to the differential debatewith perversion and the social modalities which could show mechanisms comparable to these individual facts. It underlines the possible  prevention of these crimes through cultural changes and a rather more likely access to prevention on the side of the victims.
Princípios da neurociência aplicados a premissas e requisitos para o projeto pautado para o bem-estar
Authors: Mariño Suzi Maria , Santos Silveira Carina
Published: March 2022

Associado às atividades criativa, artística, técnica/tecnológica e de gestão, o design busca o atendimento às necessidades humanas mutáveis, que indicam constante atualização do olhar projetual. Ao considerar as dimensões da prática projetual do designer, perpassando pelas funções, requisitos e atributos do produto, objetiva-se com esta pesquisa a ampliação do olhar projetual para uma “quarta prática”, relacionada à busca do bem-estar prolongado, baseada na aplicação de requisitos associados às funções sensíveis e emocionais. Toma-se como questão norteadora à condução desta pesquisa, o por que os produtos deixam de dar prazer depois de um tempo de uso, resultando em perda de interesse pelos usuários. As pesquisas bibliográficas na área da neurociência e do design, permitiram levantamento e análise de dados correlatos, no que tange a memória, interação emocional das pessoas com os produtos e fisiologia para o bem-estar. Tem-se como resultado desta pesquisa o levantamento de premissas, para o entendimento do percurso historiográfico pojetual do design, da neurociência e suas proposições; e a relação requisitos para o projeto pautado para o bem-estar.
El desarrollo de proyectos integrales como herramienta en la educación 4.0
Authors: Castañeda Ibarra Raquel , Valle Escobedo Rocío Mabeline , García Gómez Laura Esther , Sifuentes Ocegueda Ana Teresa
Published: March 2022

Education 4.0 requires human resources that are proactive, critical and linked to society at local, state, national and international levels. In view of this need for change, the present work has as its objective demonstrate relevance of an integrative project as a pedagogical strategy in teaching-learning, for the appropriation of knowledge, as well as for the development of transversal skills in higher education students, through the collaboration of three learning units belonging to the Marketing Degree of the Academic Unit of Accounting and Administration (UACyA) of the Autonomous University of Nayarit (UAN). Therefore, it is based on documentary research with a qualitative approach, exploratory and descriptive scope, a field research was also carried out with the M5-1 group, with the collaboration of their teachers, obtaining as a result marketing prospects for the companies that accepted the intervention. It concludes with the theoretical foundation in relation to the benefit and the impulse given by this practice in favor of the development of talents in university education.
Narrativas de experiências de práticas de ensino em matemática na educação básica e superior, contadas por professoras
Authors: Alves de Oliveira Sandra , Fernandes do Carmo Adriana , Lima Bertrand Luiz Corrêa , Carneiro Reginaldo Fernando
Published: March 2022

Neste artigo, compartilham-se histórias de experiências que constituíram as práticas de ensino em matemática na educação básica e superior, vividas e contadas por professoras, nas relações individuais e sociais estabelecidas com outros nos processos formativos. O objetivo deste texto é analisar essas experiências por elas narradas e vividas nos lugares de formação em que se direcionam introspectivamente, extrospectivamente, retrospectivamente e prospectivamente.  O compartilhamento dessas vivências ocorreu por meio de uma entrevista narrativa realizada com a participação de quatro professoras nos encontros do Grupo de Estudos e Pesquisas xxx da xxx durante o segundo semestre de 2019. As análises dos dados possibilitaram ao grupo reviver, rememorar e partilhar experiências de suas práticas em aulas de matemática no estágio supervisionado no 1.° ano do ensino fundamental, no curso de formação em Pedagogia, no Pacto Nacional pela Alfabetização na Idade Certa (PNAIC), no projeto desenvolvido nos anos finais do ensino fundamental e em aulas de matemática. Viver, contar e sentir essas práticas nos encontros formativos com os pares, proporcionou o aprofundamento de conhecimentos teóricos e práticos da matemática para (re)pensar as experiências no contexto da sala de aula.
Perendaman Sari Belimbing Wuluh dengan Konsentrasi Berbeda terhadap Nilai pH dan Kadar Air Daging Paha Itik Magelang
Authors: Nur ‘Azizah Athi’ , Hidayah Nur , Bayuaji Pramono Pradipta
Published: March 2022

Magelang duck is a native duck from Magelang Regency in Central Java. Duck meat has a higher fat content than chicken meat, making it more perishable. Meat quality can be maintained in various ways, one of them is using bilimbi fruit (Averrhoa bilimbi L.). The purpose of this study was to find out whether there was a differences in bilimbi fruit concentration in maintaning quality meat can lower pH value and water content of Magelang duck thigh meat. The ducks used in this study were two months old. This study used a Completely Randomized Experimental Design (CRD) with 4 treatments and 5 replications, then proceed with Duncan's Multiple Range Test (DMRT) if the treatments were different. The result showed that soaking bilimbi fruit for 30 minutes at a concentration difference of 20-60% significantly reduced the pH value of the Magelang duck thigh meat to 4,55-4,91, compared to 5,75 for controls. The water content did not affected by 57,01-59,85 value. The concentration of bilimbi fruit up to 60% was able to reduce the pH value of the Magelang duck thigh meat, but did not have an effect on the water content of the Magelang duck thigh meat.
Keywords: bilimbi fruit, magelang duck, water content, pH value.
Efektivitas Sari Belimbing Wuluh terhadap Daya Ikat Air dan Susut Masak Daging Paha Itik Magelang
Authors: Mayasari Fitria , Hidayah Nur , Haris Septian M.
Published: March 2022

Duck is a type of poultry that can be consumed as a new option other than chicken meat. Several types of local ducks can be utilized their potential for community consumption, one of which is Magelang duck. Duck meat is one of the foodstuffs of livestock origin that contains nutrients that are good for the human body. The weakness of meat with a high nutritional content that can cause meat susceptible to contamination by decaying microorganisms. Efforts to maintain meat quality are to prevent microbial contamination of Magelang duck meat by using bilimbi fruit liquid (Averrhoa bilimbi L.) to maintain the quality of duck meat. This study aims to determine the efficiency using bilimbi fruit liquid with different concentrations on the value of water holding capacity and cooking loss of Magelang duck thigh meat. The experiment plan used in this study was a Completely Randomized Experimental Design (CRD) with 4 treatments differences concentration of using bilimbi fruit liquid (0, 20, 40, 60%) and 5 replays with immersion for 30 minutes. The data obtained was analyzed with a variety analysis (ANOVA) and the apparent differences between treatments were analyzed with the Duncan Multiple Range Test (DMRT) advanced test. The results showed that soaking magelang duck thigh meat up to a concentration of 60% of using bilimbi fruit liquid for 30 minutes did not give a noticeable influence or has not been able to increase DIA and decrease cooking. The range of DIA values in this study is 40.67˗44.93% and cooked stacking 47.19–52.37%.

Keywords: magelang duck, water holding capacity, starfruit juice, cooking loss.
3D printing and testing of rose thorns or limpet teeth inspired anchor device for tendon tissue repair
Authors: Rodriguez Reinoso Mariana , Civera Marco , Burgio Vito , Bergamin Federica , Grimaldo Ruiz Oliver , Pugno Nicola Maria , Surace Cecilia
Published: March 2022

Purposes: Advancements in medical technology have enabled medical specialists to resolve significant problems concerning tendon injuries. However, despite the latest improvements, surgical tendon repair remains challenging. This study aimed to explore the capabilities of the current state-of-the-art technologies for implantable devices. Methods: After performing extensive patent landscaping and literature review, an anchored tissue fixation device was deemed the most suitable candidate. This design was firstly investigated numerically, realizing a Finite Element Model of the device anchored to two swine tendons stumps, to simulate its application on a severed tendon. Two different hook designs, both bio-inspired, were tested while retaining the same device geometry and anchoring strategy. Then, the applicability of a 3D-printed prototype was tested on swine tendons. Finally, the device-tendon stumps ensemble was subjected to uniaxial tensile tests. Results: The results show that the investigated device enables a better load distribution during the immobilized limb period in comparison to standard suture-based approaches, yet it still presents several design flaws. Conclusions: The current implantable solutions do not ensure an optimal result in terms of strength recovery. This and other weak points of the currently available proposals will serve as a starting point for future works on bio-inspired implantable devices for tendon repair.
Changes in postural stability on balance platform in patients after meniscal repair – two years follow up
Authors: Żmijewska Kinga , Fąfara Alicja , Feluś Jarosław , Mikos Magdalena , Nawara Jolanta , Gądek Artur
Published: March 2022

Purpose: The aim of this work was to evaluate postural stability on the balance platform averagely 2 years following meniscal repair. Methods: This is a retrospective, case-control comparative analysis of patients who underwent surgical repair for the isolated longitudinal traumatic meniscal tear versus matched healthy controls. The study group consisted of 30 patients (mean age 29.93 years; averagely 2.3 years after surgery) and the control group – of 30 people. Following physical examination and completion of the IKDC, and the Lysholm questionnaires, the evaluation of the postural stability using two single-leg stabilometry tests was performed. In the static test, the analyzed variables included deviations from the horizontal, vertical axes and the length of the balance path travelled. In the dynamic test, the length of the path travelled and the time to complete task were recorded. Between-limb and between-groups comparison of collected stabilometry tests were performed. Additionally, the IKDC and the Lysholm questionnaires scores were compared between the study and heathy groups. Results: No abnormalities were found on clinical examination in the study group nor any differences between the operated and contralateral knee (p > 0.05). In stabilometry: (1) in the study group, the operated extremity scored worse than the contralateral limb (length of path traveled in: A) static test x = 56.7 cm SD = 37.91 cm vs. x = 21.6 cm SD = 9.06 cm; p = 0.002 and B) dynamic test x = 82.57 cm, SD = 50.43 cm vs. x = 53.32 cm, SD = 13.82 cm; p = 0.003); (2) In the control group, no leg-related differences were noted (p > 0.05); (3) Between-group comparison revealed that the study group scored worse than the control group (length of path traveled in: A) static test x = 56.7 cm, SD = 37.91 cm vs. x = 17.23 cm, SD = 3.39 cm; p = 0.001 and B) dynamic test x = 82.57 cm, SD = 50.43 cm vs. x = 32.13 cm, SD = 9.41 cm; p < 0.001). Study group scored worse on IKDC scores (p < 0.001) but not on Lysholm score (p > 0.05). Conclusions: Postural stability deficit persists despite a successful meniscal repair.
Assessment of the lower limb biomechanics in patients after tibiofibular syndesmosis injury treatment
Authors: Klepacki Krzysztof , Kowal Igor , Konieczny Grzegorz , Tomczyk Łukasz , Ciszewski Mariusz , Reichert Paweł , Morasiewicz Piotr
Published: March 2022

Purpose: There is no consensus as to the number of bone cortices engaged in tibiofibular syndesmosis treatment. The purpose of our study was to assess the weight distribution on the lower limbs after tricortical or quadricortical syndesmosis fixation and different timing of screw removal. Methods: A total of 55 patients who underwent treatment for acute tibiofibular syndesmosis injury were analyzed in this study. The Zebris pedobarographic platform was used to measure the distribution of body weight on the lower limbs. The study population was stratified by the time to syndesmotic screw removal (8–15 weeks versus 16–22 weeks) and the number of bone cortices involved in fixation (three [tricortical fixation] versus four [quadricortical fixation]). Results: The weight distribution on the operated and healthy limbs in patients with tricortical syndesmosis fixation was asymmetrical, with the mean load on the operated and healthy limbs of 48.38% and 51.62%, respectively. The patients who underwent quadricortical syndesmosis fixation exhibited a symmetrical distribution of weight on the operated and healthy limb. There was a symmetrical distribution of the load of body weight on the operated and healthy limbs both in the group with different times to syndesmotic screw removal. Conclusion: Tricortical syndesmosis fixation is associated with an asymmetrical weight distribution on the operated and healthy limbs. In treating tibiofibular syndesmosis injuries, based on our pedobarographic research, quadricortical syndesmosis fixation and leaving the syndesmotic screw in place for up to 15 weeks, seems more beneficial to the patient.