bluuebunny/crossref_metadata_2025 huggingface dataset:
Disentangling the hydrological and hydraulic controls on streamflow variability in Energy Exascale Earth System Model (E3SM) V2 – a case study in the Pantanal region
Authors: Xu Donghui , Bisht Gautam , Tan Zeli , Liao Chang , Zhou Tian , Li Hong-Yi , Leung L. Ruby
Published: February 2024

Abstract. Streamflow variability plays a crucial role in shaping the dynamics and sustainability of Earth's ecosystems, which can be simulated and projected by a river routing model coupled with a land surface model. However, the simulation of streamflow at large scales is subject to considerable uncertainties, primarily arising from two related processes: runoff generation (hydrological process) and river routing (hydraulic process). While both processes have impacts on streamflow variability, previous studies only calibrated one of the two processes to reduce biases in the simulated streamflow. Calibration focusing only on one process can result in unrealistic parameter values to compensate for the bias resulting from the other process; thus other water-related variables remain poorly simulated. In this study, we performed several experiments with the land and river components of the Energy Exascale Earth System Model (E3SM) over the Pantanal region to disentangle the hydrological and hydraulic controls on streamflow variability in coupled land–river simulations. Our results show that the generation of subsurface runoff is the most important factor for streamflow variability contributed by the runoff generation process, while floodplain storage effect and main-channel roughness have significant impacts on streamflow variability through the river routing process. We further propose a two-step procedure to robustly calibrate the two processes together. The impacts of runoff generation and river routing on streamflow are appropriately addressed with the two-step calibration, which may be adopted by developers of land surface and earth system models to improve the modeling of streamflow.
Evaporative controls on Antarctic precipitation: an ECHAM6 model study using innovative water tracer diagnostics
Authors: Gao Qinggang , Sime Louise C. , McLaren Alison J. , Bracegirdle Thomas J. , Capron Emilie , Rhodes Rachael H. , Steen-Larsen Hans Christian , Shi Xiaoxu , Werner Martin
Published: February 2024

Abstract. Improving our understanding of the controls on Antarctic precipitation is critical for gaining insights into past and future polar and global environmental changes. Here we develop innovative water tracing diagnostics in the atmospheric general circulation model ECHAM6. These tracers provide new detailed information on moisture source locations and properties of Antarctic precipitation. In the preindustrial simulation, annual mean Antarctic precipitation originating from the open ocean has a source latitude range of 49–35∘ S, a source sea surface temperature range of 9.8–16.3 ∘C, a source 2 m relative humidity range of 75.6 %–83.3 %, and a source 10 m wind velocity (vel10) range of 10.1 to 11.3 m s−1. These results are consistent with estimates from existing literature. Central Antarctic precipitation is sourced from more equatorward (distant) sources via elevated transport pathways compared to coastal Antarctic precipitation. This has been attributed to a moist isentropic framework; i.e. poleward vapour transport tends to follow constant equivalent potential temperature. However, we find notable deviations from this tendency especially in the lower troposphere, likely due to radiative cooling. Heavy precipitation is sourced by longer-range moisture transport: it comes from 2.9∘ (300 km, averaged over Antarctica) more equatorward (distant) sources compared to the rest of precipitation. Precipitation during negative phases of the Southern Annular Mode (SAM) also comes from more equatorward moisture sources (by 2.4∘, averaged over Antarctica) compared to precipitation during positive SAM phases, likely due to amplified planetary waves during negative SAM phases. Moreover, source vel10 of annual mean precipitation is on average 2.1 m s−1 higher than annual mean vel10 at moisture source locations from which the precipitation originates. This shows that the evaporation of moisture driving Antarctic precipitation occurs under windier conditions than average. We quantified this dynamic control of Southern Ocean surface wind on moisture availability for Antarctic precipitation. Overall, the innovative water tracing diagnostics enhance our understanding of the controlling factors of Antarctic precipitation.
Brief communication: Rapid acceleration of the Brunt Ice Shelf after calving of iceberg A-81
Authors: Marsh Oliver J. , Luckman Adrian J. , Hodgson Dominic A.
Published: February 2024

Abstract. The Brunt Ice Shelf, Antarctica, accelerated rapidly from a velocity of 900 to 1500 m a−1 during 6 months, following calving of a 1500 km2 iceberg on 22 January 2023. The immediate response to calving was observed as a change to the rate of acceleration and not to velocity directly. Acceleration increased by a factor of 10, with a second, smaller calving at the end of June 2023, leading to further tripling of acceleration. The acceleration was caused by the reduction of buttressing at the McDonald Ice Rumples, leading to high localised strain rates, which reduce the strength of the remaining ice shelf.
Comparative evaluation of Indocyanine Green and 810nm Diode Laser Assisted Antimicrobial Photodynamic Therapy with 810nm Diode Laser Assisted New Attachment Procedure as adjuncts to Scaling and Root Planning in Supportive Periodontal Therapy: A Randomized Controlled Split-Mouth Clinical Trial
Authors: Gottumukkala Sruthima NVS , Veluri Sathya Valli , Penmetsa Gautami Subhadra , KSV Ramesh , Pasupuleti Mohan Kumar , Gera Dinesh , Vundavalli Sravanthi
Published: February 2024

BACKGROUND: Minimally invasive nonsurgical management of recurrent periodontal pockets remains the most viable option during supportive periodontal therapy (SPT), but with inconclusive results. The purpose of this study is to evaluate and compare the adjunctive use of Indocyanine green (ICG) and 810nm Diode laser assisted photodynamic therapy (IG-PDT) with 810nm Diode laser assisted new attachment procedure (LANAP) in the management of persistent pockets in SPT.
MATERIALS AND METHODS: This single blinded randomized controlled split mouth clinical trial included 20 participants with at least two adjacent teeth with PPD ≥5mm and Clinical attachment level (CAL) ≥3mm in the contralateral quadrants. IG-PDT group received application of 5mg/ml solution of ICG for one minute followed by 810±10nm diode laser with 1W power density. LANAP group received 810±10nm diode laser application at 3W power density with 100ms and 650ms pulse duration at two consecutive passes. Clinical parameters i.e., Plaque index (PI), Gingival index (GI), PPD, CAL gain were recorded at baseline, 3 and 6 months. Landry’s Healing index was assessed on the 7th day and 1 month postoperatively. Patient comfort was assessed using Visual Analog Scale (VAS) immediate post-operatively.
RESULTS: Student t test and repeated measures of ANOVA were used for statistical analysis. Both site level and patient level assessments of clinical parameters showed improvement in clinical parameters in both groups. However, IG-PDT group showed significantly greater improvements in PPD (<0.001) and CAL (<0.001) at 3 and 6 months evaluation. IG-PDT showed better healing (P-0.03) at 7th post-operative day. However, LANAP showed less discomfort (2.40±0.50) compared to IG-PDT group (3.20±0.61).
CONCLUSION: IG-PDT is shown to provide better clinical outcomes compared to LANAP in management of patients under SPT.
KORELASI FUNGSI AFEKTIF KELUARGA DAN EFIKASI DIRI TERHADAP KEPATUHAN MINUM OBAT TUBERKULOSIS PARU
Authors: Chandra Tri  , Mandasari Erliana
Published: February 2024

Tuberkulosis paru adalah penyakit kronis yang disebabkan oleh Mycobacterium tuberculosis yang memerlukan pengobatan jangka panjang selama 6 bulan atau lebih untuk mencapai kesembuhan; ketidakpatuhan terhadap pengobatan dapat menyebabkan resistensi obat dan kemungkinan kematian. Kepatuhan minum obat anti tuberkulosis dapat dipengaruhi oleh dorongan keluarga dan rasa efikasi diri. Tujuan dari penelitian ini adalah untuk menguji hubungan fungsi afektif keluarga dan efikasi diri dengan kepatuhan minum obat anti tuberkulosis. Literatur review non systematic digunakan sebagai metode penelitian. Literatur diperoleh dengan mengkaji publikasi yang terkait dengan masalah penelitian dan memenuhi kriteria inklusi. Pencarian literatur menggunakan web internet yang diterbitkan antara tahun 2016-2020. Dalam pencarian literatur, frasa "tuberkulosis", "dukungan keluarga", "emosi keluarga", "kemanjuran diri", "kepatuhan penyembuhan", dan "kepatuhan pengobatan" digunakan. Berdasarkan hasil pencarian, menunjukkan bahwa 28 literatur sesuai dengan kriteria inklusi yang telah ditetapkan. Setelah dianalisis hasil menunjukkan bahwa terdapat hubungan antara fungsi afektif keluarga dan efikasi diri dengan kepatuhan minum obat anti tuberkulosis.

Kata kunci: Efikasi Diri, Fungsi Afektif Keluarga, Kepatuhan Minum Obat Anti Tuberkulosis
HUBUNGAN PENERIMAAN DIRI DENGAN KUALITAS HIDUP PASIEN KANKER PAYUDARA DI RSUP. PROF DR. R.D KANDOU
Authors: Sembiring Erika Emnina , Ferlan Ansye Pondaag  , Adriani Natalia M
Published: February 2024

Kanker payudara dan pengobatannya menimbulkan masalah serius pada psikologis pasien yaitu seperti harga diri dan perasaan bangga yang rendah, cemas, bahkan depresi serta tidak siap menerima kondisi penyakit yang saat ini dialami. Pasien kanker payudara dengan penerimaan diri rendah cenderung mengalami perasaan tertekan, gangguan citra tubuh dan penurunan kualitas hidup. Kualitas hidup dapat menjadi parameter yang penting dalam menilai seberapa baik keberfungsian seseorang setelah didiagnosa dan menjalani terapi pengobatan. Tujuan penelitian ini untuk menguji korelasi penerimaan diri dengan kualitas hidup pasien kanker payudara. Penelitian ini merupakan penelitian deskripsi dengan metode cross sectional. Consecutive sampling merupakan teknik pengambilan sampel dalam penelitian ini dengan jumlah sampel 74 pasien kanker payudara yang dirawat di RSUP Prof. DR. R.D Kandou. Alat ukur yang digunakan berupa kuesioner Acceptance of Illnes Scale untuk menilai penerimaan diri pasien dan EORTC QLQ C-30 untuk menilai kualitas hidup pasien. Analisa data univariat berupa statistik deskriptif dan analisa data bivariat menggunakan uji Spearman. Hasil penelitian didapatkan data lebih dari setengah yaitu 51,4% pasien kanker payudara memiliki penerimaan diri sedang dan hampir seluruhnya yaitu 91,9% pasien kanker payudara memiliki kualitas hidup sedang. Berdasarkan uji statistik Spearman menunjukkan bahwa penerimaan diri berkorelasi dengan kualitas hidup pasien kanker payudara (p < 0,05). Semakin baik penerimaan diri maka semakin baik pula kualitas hidup pasien kanker payudara. Penerimaan diri dan kualitasi hidup pasien kanker payudara perlu untuk ditingkatkan hal ini bertujuan untuk membuat pasien memiliki semangat dalam menjalani program terapi dan memiliki motivasi yang tinggi untuk sembuh.
Ökonomische Instrumente in der Stadtentwicklung. Bewertung ausgewählter Instrumente am Beispiel Wiens. Unter Mitarbeit von Mina Chamraci, Johann Bröthaler, Arzu Sedef, Lucas Haring und Felicia Schartner
Authors: Damjanovic Dragana , Getzner Michael , Kalhorn Anna F. , Wagner Dominik
Published: February 2024

Ökonomische Instrumente wie Umweltsteuern und Subventionen können die Ziele einer nachhaltigen, resilienten, klimaneutralen und gerechten Stadtentwicklung wesentlich unterstützen. Um Wien als lebenswerte Stadt weiter zu erhalten und zu fördern, stellt dieses Buch die rechtlichen und wirtschaftswissenschaftlichen Grundlagen dieser Instrumente dar, schlägt für Wien eine Reihe konkreter Maßnahmen in den Bereichen Wohnen, Mobilität und Wirtschaft vor, um verschiedene Lücken einer nachhaltigkeitsorientierten Stadtpolitik zu schließen, und bewertet diese anhand eines umfangreichen Kriterienkatalogs.
SISTEM INFORMASI PENJUALAN SMARTPHONE PADA TOKO MEDIA CELLS STORE BERBASIS WEB
Authors: Manuaron Yoel Hanssen , Robo Salahudin
Published: February 2024

Toko Media Cells Ialah sebuah tempat penjualan barang berupa smartphone yang bertempatan atau berlokasi di Jl. Ahmad Yani No.22, Kota Jayapura. Dalam tempat usaha ini terdapat sebuah permasalahan yang membuat perkembangan dari toko ini terhambat, permasalahan tersebuat ialah sistem penjualan dan pemberian informasi penjualan yang masih menggunakan cara konvensional. Cara konvensional yang dimaksud seperti pemberian brosur penjualan barang dan pendataan barang yang terjual masih di catat di buku. Tujuan penelitian ini ialah untuk membuat sebuah sistem penjualan dan penampilan barang yang terjual di Toko Media Cells. Metode yang dipakai pada pengembangan sistem menggunakan Metode Waterfall, sedangkan dalam perancangan sistem atau perancangan kerangka sistem mengunakan perangangan UML sedangkan untuk perancangan analisis menggunakan Metode Komparatif. Dalam penggunaan atau akses penguna yang di beri izin ialah  Admin dan Pelanggan. Hasil yang diberikan dari penelitian ini ialah memberikan sebuah sistem penjualan smartphone yang memberi akses transaksi secara real-time. untuk peningkatan dari sistem masih berakses melalui browser saja, di harapkan sistem bisa di kembangkan dan di tingkatkan ke dalam multi-platform agar akses informasi dari toko bisa di nikmati di berbagai bentuk platform.
Penerapan Metode Signature Base Berbasis IDS Snort dan IDS Suricata Pada Keamaan Jaringan Laboratorium Komputer.
Authors: Sangadji Viviyanti Iksan , Muhammad Abdul Haris , Gunawan Erwin
Published: February 2024

Keamanan komputer dapat diartikan sebagai perlindungan sistem komputer dari bahaya yang datang melalui akses jaringan yang menyimpang dari prosedur keamanan. seperti halnya komputer yang terhubung ke jaringan internet, berpotensi sangat rentan datanya diambil dari pihak yg tidak bertanggung jawab. Universitas Muhammadiyah Maluku Utara (UMMU) contohnya, salah satu perguruan tinggi di maluku utara yang mempunyai sistem jaringan dan server di Laboratorium IT Infrastructure program studi Teknik Informatika yg digunakan dalam pengelolaan jaringan dan internet yang rentan akan pencurian data dan informasi. Permasalahan yg diangkat pada penelitian ini adalah bagaimana upaya untuk meningkatkan keamanan sistem jaringan komputer pada Laboratorium IT Infrastructure program studi Teknik Informatika. Metode signature based berbasis IDS adalah metode dalam mendeteksi serangan melalui pola atau paket data yg dibaca lalu dibandingkan menggunakan data atau paket yang telah tersimpan dalam database yang terdapat atau rule yang telah ada. Tujuan penelitian ini ialah menghasilkan sebuah sistem yang bisa melakukan pendeteksian terhadap traffic jaringan dan hal-hal yg mencurigakan didalam sebuah sistem jaringan. Dari hasil analisis yang dilakukan, Snort mendeteksi serangan dengan pemakaian CPU hingga mencapai 50% serta penggunaan memory mencapai 470 Mega. Sedangkan Suricata mendeteksi serangan dengan pemakaian CPU hampir mencapai 100% dengan penggunaan memory mencapai 430 Mega. Jadi kesimpulannya jumlah pemakaian CPU snort lebih kecil dibandingkan dengan Suricata. Pemakaian CPU snort hanya sebatas 50%. Sedangkan suricata hampir mencapai 100%. Untuk pemakaian memory snort dan suricata sama-sama hemat dalam pemakaian memory. Untuk snort pemakaian memory mencapai hingga 470 Mega, sedangkan suricata mencapai hingga 430 Mega.
Implementasi Cloud Computing Sebagai Layanan Mail Server
Authors: R. Buhay Julianti , Ibrahim Adelina , N. Elyas M Ikhwan
Published: February 2024

Mail server merupakan program berbasis sistem cloud computing untuk penyedian mengirim dan juga menerima pesan email melalui jaringan server email yang sama. Zimbra adalah perangkat lunak yang berbasis open source untuk mail server yang memiliki fitur yang lengkap dan powerfull sehingga dapat digunakan untuk aplikasi mail server, serta dapat mendukung dalam instalasi maupun manajemen mail server. pada Prodi Teknik Informatika hanya menggunakan gmail, dimana jika pengiriman dan penerimaan email terlalu banyak dalam satu hari, maka menyebabkan akses email akan terasa lambat sehingga terjadi mekanisme server terbebani karena pada saat yang bersamaan. maka tujuan dari penelitian ini adalah merancang dan mengimplementasikan cloud computing untuk penyedian mail server menggunakan zimbra pada Prodi Teknik Informatika agar dapat membantu dalam komunikasi berkirim pesan menjadi lebih mudah. Metode dalam penelitian ini yang digunakan adalah implementasi mail server menggunakan zimbra yang terdapat pada sistem operasi ubuntu 20.04 yang dibangun dalam jaringan berbasis Local Area Network (LAN). Dari hasil implementasi serta pengujian yang dilakukan dapat diketahui bahwa zimbra berhasil diakses oleh admin dan client menggunakan web browser dengan mengakses, serta pengiriman email dan penerimaan email berhasil dilakukan.
Sistem Monitoring lab Komputer Sekolah SMA Negeri 6 Tikep Berbasis Esp-32 Cam dan Telegram
Authors: Hidayat Supriyadin , Hamid Mustamin , Santosa Santosa
Published: February 2024

Lembaga atau organisasi pendidikan yang menyelenggarakan kegiatan pendidikan di dalam sekolah disebut sekolah. Selain itu, terdapat ruang lab komputer yang dapat digunakan sebagai wadah atau tempat praktik. Akibatnya, ruang lab perlu diamankan. Jika dibandingkan dengan teknologi yang ada saat ini, pengamanan yang hanya dilakukan secara manual atau konvensional sangatlah tidak praktis. Keamanan di ruang pribadi atau laboratorium sekolah adalah salah satunya. Rancangan sistem keamanan ruang lab berbasis Esp-32 Cam dan Telegram menjadi tujuan dari penelitian ini. Dalam penelitian ini akan memberikan manfaat serta keamanan yang lebih kepada pengguna di  sekolah. Metode yang di gunakan dalam penelitian ini merupakan Metode waterfall jenis penelitan ini adalah Penelitian experiment, hasil dari alat yang di uji coba semua alat atau perangkat pengaman ruang lab yaitu  Esp-32cam dan beberapa komponen lainnya dapat berfungsi dengan baik. Dari hasil pengujian menggunakan 2 cara yaitu cara pertama dengan menggunakan pesan perintah dan cara ke dua menggunakan deteksi gerakan.
Housing Policy, Urbanization, and the Production of Homelessness in Greenland
Authors: Christensen Julia , Arnfjord Steven , Aastrup Marie-Louise , Stephenson Eleanor
Published: February 2024

Visible homelessness is on the rise in Nuuk, Greenland. Since the early 2000s, the number of people staying at the municipal shelter, accessing support programs, and registering as homeless in the community has, by a qualitative estimate grown. Attention has also been given to the growing number of Greenlanders living homeless in Danish cities. However, the literature on Greenlandic homelessness remains sparse, and very little literature conceptualizes homelessness in Greenland within its specific geographical, cultural, or social context. To better understand the emergence of visible homelessness, this article explores the social dimensions of homelessness and asks how homelessness can be understood within the dynamics of urbanization in Greenland. Drawing on four years of participant observation in Nuuk with homelessness outreach organizations, and 20 in-depth interviews with both service providers and men and women experiencing homelessness, and four lived experience focus groups, we find that the emergence of homelessness in Greenland is part and parcel of a trajectory of welfare colonialism, resettlement, and contemporary urbanization. We highlight four specific policy issues: 1) an existing housing stock in Nuuk inappropriate for diverse needs; 2) urbanization in the absence of a national housing or homelessness strategy; 3) a lack of integrated supports and reliance on the non-profit sector; 4) and an increasingly punitive approach to managing the limited housing supply. Stepping back, we argue that the emergence of visible northern homelessness is an important lens through which to understand the dynamics of northern urbanization, social marginalization and exclusion, and the continuation of colonial relations in the era of self-governance.
Athletes’ Stress and Anxiety Before The Match
Authors: S Adi , Aliriad Hilmy , Wira Yudha Kusuma Donny , Arbanisa Wahyu , Winoto Ahmad
Published: February 2024

Studi purpose. Stress and anxiety are every day for athletes, but they need severe treatment. Pre-match anxiety is often present and quite disruptive to an athlete's performance. Anxiety is inherent in sports and may be experienced at all levels. This study examines the effects of stress and anxiety before the match.
Materials and methods. This study used the article review method by collecting qualitative and quantitative data through reputable journal articles. This article reviewed the literature on athlete stress and anxiety leading to a match. Research with this article review method used relevant and accurate data to be used as material for readers.
Results. The results of the review concluded that athletes who experienced high levels of stress have the effect of a 70% higher risk of injury, and increased anxiety could harm athlete performance during matches. The causes of anxiety in athletes before competing included competitive anxiety, cognitive anxiety, and somatic anxiety.
Conclusions. In conclusion, athletes will experience symptoms of anxiety and stress in the match due to various things, such as the presence of thousands of spectators who can threaten the athlete's self-esteem and the negative judgment of the community towards losing athletes.
Laporan Kasus: Penanganan Nyeri Neuropati diabetik Dengan Menggunakan Terapi Musik
Authors: Suryadi Mohammad Shiddiq , Jatimi Atika , Sudindi Qomaruddin
Published: February 2024

Introduction; Diabetic neuropathy pain is a complication that is often experienced by diabetes mellitus sufferers who complain of pain in the extremities due to increased blood glucose levels. Objective; to describe the effectiveness of providing music therapy to clients experiencing diabetic neuropathy pain. Method; The implementation of this case study uses a nursing process approach through five stages, namely assessment, establishing a nursing diagnosis, developing interventions, implementing nursing plans and evaluating the results of actions. Patients were selected using a purposive sampling method, with action carried out in the community. Results; After applying music therapy three times, clients who experienced diabetic neuropathy pain experienced an improvement in their health condition which was marked by a decrease in pain. Conclusion; The results of the evaluation after implementing the action on a client diagnosed with diabetes mellitus who complained of diabetic neuropathy pain showed that the nursing problem was resolved.
Karite Ürünlerinin Besinsel Faydaları ve Karite Yağının Tıbbi Özellikleri
Authors: KARACA Esra , GÜZEL KARA Sevda
Published: February 2024

Karite Ürünlerinin Besinsel Faydaları ve Karite Yağının Tıbbi Özellikleri

ÖZET

Karite veya Shea ağacı, Vitellaria paradoxa (Syn: Butyrospermum paradoxum, B. paradoxa, B. parkii) (Sapotaceae), Batı Afrika’nın kuru savan kuşağında doğal olarak yetişir. V. paradoxa subsp. paradoxa ve V. paradoxa subsp. nilotica olmak üzere iki alt türü tanımlanmıştır. Ağaç farklı ülkelerde farklı isimlerle bilinir. Karite ağacının önemi yüzyıllar önce meyvesi, çekirdekleri ve yağı aracılığıyla anlaşılmıştır. Günümüzde ise karite ağacı büyük bir ekonomik potansiyele sahiptir. Geleneksel olarak bitkinin farklı kısımlarının çok çeşitli kullanımları kayıtlıdır. Yağ; gıda hazırlama, ilaç ve kozmetik endüstrisinde kullanılır. Yağın ve yağdan izole edilen bileşiklerin anti-inflamatuvar, antimikrobiyal, antioksidan, anti-diyareik, anti-arthritik, antitümör, UV-koruyucu, emoliyan, nemlendirici, yaşlanma karşıtı ve proteaz inhibisyon etkilerinin olduğu çeşitli araştırmalarda gösterilmiştir. Ayrıca yağın kolesterol ve protein metabolizması üzerine etkisi bildirilmiştir. Yağ sabunlaşmayan maddelerin yüksek yüzdesi nedeniyle uluslararası kozmetik endüstrisinde oldukça talep görmektedir. Bu çalışmada; karite ağacının yayılışı, geleneksel kullanımı, ağaçtan elde edile meyve, çekirdek ve yağın kimyasal içerikleri; besinsel faydaları ve yağın tıbbi özellikleri ve kullanım alanları ile ilgili güncel bilgiler derlenmiştir.

Anahtar Kelimeler: Vitellaria paradoxa, karite yağı, doğal kozmetik, kimyasal içerik, yemeklik yağ
Cıva Maruziyetinin Nörodejeneratif Hastalıklar Üzerindeki Etkisi
Authors: DURU Elif , TEZEL Hülya , ÇAKIR Deniz Arca , BAYDAR Terken , ERKEKOĞLU Pınar
Published: February 2024

Çevre kirliliği nedeniyle insanlar günlük yaşamlarında cıva da dahil olmak üzere çeşitli ağır metallere maruz kalmaktadır. Cıva doğada yaygın olarak bulunur ve termometrelerde, barometrelerde, diş dolgularında kullanılır. Toksik bir ağır metaldir ve farklı mekanizmalarla toksik etkileri olan üç farklı formda bulunur. Cıvaya maruz kalınması proteinlerin yapısında bozulma, reaktif oksijen türlerinde artma ve enzim inhibisyonu gibi çeşitli toksik etkilere yol açar. Nörodejeneratif bozuklukların, kusurlu protein yıkımı ve agregasyonu, oksidatif stres ve serbest radikal oluşumu ile ilgili mitokondriyal işlev bozukluğu ve metal toksisitesi nedeniyle ortaya çıktığı ileri sürülmektedir. Cıva ve bileşiklerinin nörodejeneratif hastalıklara neden olduğuna dair çeşitli kanıtlar vardır. Cıva maruziyeti nedeniyle DNA parçalanması ve nöronların bütünlüğünün bozulması gibi toksik etkiler gözlenebilir. Nöronların ciddi şekilde hasar görmesi nöronal kayıplara neden olurken, nöronal kayıplar nörodejeneratif hastalıkların görülmesini kaçınılmaz kılmaktadır. Bu derlemede, başlıca nörodejeneratif hastalıklardan Alzheimer hastalığı, Parkinson hastalığı, amyotrofik lateral skleroz ve multipl skleroz hastalıklarının cıva maruziyeti ile ilişkili olup olmadığı konusunda yapılan araştırmalar özetlenmiştir. Çalışmalar, cıva maruziyetinin başta Alzheimer hastalığı olmak üzere tüm nörodejeneratif hastalıklarla ilişkili olabileceğini göstermiştir. Özetle, cıvanın nörodejenerasyon ve buna bağlı patolojik durumlar ile ilişkili olabileceği ifade edilebilir.
The Genesis of the Zionist Paradigm in Jewish History: Exploring Ben-Zion Dinur's Worldview
Authors: Ruzhansky Vladimir
Published: February 2024

The 1920s and 30s marked a pivotal period for the genesis of the modern Jewish state and its historical narrative. It was during this era that the Zionist paradigm of Jewish history took shape, serving as the cornerstone of collective memory and the bedrock of national identity for successive generations of Israelis. The initial cohort of Zionist historians astutely grasped the pivotal role of historical scholarship in shaping a national identity, particularly in advancing the Zionist ambition of rejuvenating the Jewish state and cultivating a novel Jewish identity - the Israeli identity. In pursuit of these aspirations, Zionist historians grappled with formidable challenges, chiefly centered around establishing a scholarly foundation validating the unity of the Jewish people and their enduring connection to the land of Israel, known as Eretz Israel. This paper endeavors to delineate the defining traits of Zionist historians during this epoch, drawing upon the prominent figure exemplifying this ethos, Professor Ben-Zion Dinur who endeavored to harmonize ideological allegiance with scholarly veracity. Furthermore, the paper delves into the fundamental elements comprising the Zionist narrative within Jewish history.
1920-30-ական թվականները նշանակալից են եղել ժամանակակից հրեական պետության և վերջինիս ստեղծման համար: Հենց այս դարաշրջանում է ձևավորվել հրեական պատմության սիոնիստական պարադիգմը, որը ծառայել է որպես հավաքական հիշողության հիմնաքար և ազգային ինքնության հիմք իսրայելցիների հաջորդական սերունդների համար: Սիոնիստ պատմաբանների սկզբնական խումբը ըմբռնեց պատմական գիտության առանցքային դերը ազգային ինքնության ձևավորման գործում հատկապես հրեական պետության երիտասարդացման սիոնիստական նկրտումներն առաջ մղելու և նոր հրեական ինքնություն՝ իսրայելական ինքնություն, մշակելու գործում: Այս ձգտումներին հետամուտ լինելով՝ սիոնիստ պատմաբանները բախվեցին ահռելի մարտահրավերների հետ, որոնք հիմնականում կենտրոնացած էին հրեա ժողովրդի միասնության և Իսրայելի երկրի հետ նրանց հարատև կապի հաստատման վրա հիմնված գիտական հիմնադրամի վրա, որը հայտնի է որպես Էրեց Իսրայել: Սույն հոդվածը փորձում է ուրվագծել այս դարաշրջանում սիոնիստ պատմաբանների որոշիչ գծերը՝ հենվելով հրեա նշանավոր գործչի՝ պրոֆեսոր Բեն-Սիոն Դինուրի վրա, ով ջանում էր ներդաշնակեցնել գաղափարական հավատարմությունը գիտական ճշմարտության հետ:
On the Question of Circumstances, Reasons and Date of Tigranes the Great Extradition as Hostage to the Parthians. A Revised Armenian Chronology of the Period 215-96 BC
Authors: Kobzar Ruslan
Published: February 2024

This article re-examines the circumstances, reasons and date of taking Tigranes II the Great into hostage by the Parthians from a new perspective. In the light of in-formation from late Babylonian cuneiform, Greco-Roman, ancient Armenian and ancient Georgian sources, the prevailing scholarly opinion that the surrender of Prince Tigranes as a hostage was due to the demands of the Parthian side following the Armenian military defeat by Parthian King Mithridates II is challenged and refuted. A new interpretation of events logically connects the accounts of Justin [25:322] and Strabo [42:336-340] regarding taking Tigranes II the Great hostage, which is confirmed by the late Babylonian cuneiform tablet, with information from Strabo [43:224-225] of successful Armenian resistance against repeated Parthian aggression.
Պատմական աղբյուրներում պարթևների Միհրդատ II և հայոց Արտավազդ արքաների միջև տեղի ունեցած պատերազմի մասին առկա տեղեկությունների և արքայազն Տիգրանի երկարատև պատանդառության փաստը հիմք ընդունելով՝ պատմաբանների կողմից վերականգնվել է մի իրավիճակ, իբր հայերը պարտություն են կրել պատերազմում և որպես իրենց ստանձնած պարտավորությունների կատարման երաշխիք ստիպված են եղել Տիգրանին պատանդ տալ պարթևներին։ Ընդհանրացնելով իր և նախորդ ուսումնասիրողների ստացած արդյունքները՝ Ռ. Լ. Մանասերյանը վերոնշյալ դեպքերն առաջարկել է թվագրել Ք.ա. 115-111 թվականների միջակայքում՝ Միհրդատ II Մեծի կողմից «արքայից արքա» տիտղոսի ստանձնման նախընթաց շրջանում։ Սակայն նման հետևությունը հակասության մեջ է մտնում Ստրաբոնի հաղորդած այն տեղեկության հետ, որ հայերը բազմիցս հաջողությամբ դիմագրավել են պաթևների հարձակումներին ու չեն նվաճվել նրանց կողմից: Հայ-պարթևական պատերազմի ընթացքն ու ելքը պատմական աղբյուրներում չի լուսաբանվում։ Դատելով Պոմպեոս Տրոգոսի «Փիլիպպոսի պատմությունը» երկի Հուստինոսի համառոտ վերաշարադրանքից և անհայտ հեղինակի նախերգանքներից՝ հեղինակը հնարավոր է համարում, որ պատերազմը տեղի ունե-ցած լինի Միհրդատ I և Արտավազդ I արքաների գահակալման շրջանում։ Ամեն դեպքում Միհրդատ II-ը չէր կարող պատերազմել Արտավազդ I-ի հետ։ Հեղինակը, հենվելով աղբյուրների վրա, ցույց է տալիս, որ հաշտություն կնքելու դեպքերից բացի, գոյություն են ունեցել պատանդ տալու այլ իրողություններ ևս, և նման իրավիճակը չի բացառվում արքայազն Տիգրանի պարագայում։
The Effect of Math-Supported Introductory Programming Education on Computational Thinking
Authors: BOZAL Muradiye , ŞENDURUR Polat
Published: February 2024

The study aims to research the effect of an introductory programming course equipped with math-based programming activities on computational thinking skills and self-efficacy. A static-groups pre-test post-test quasi-experimental design was used. One hundred seventy-six 6th-grade students of a public school participated in the study. Eighty-nine of these students were in the experimental group, and 87 were in the control group. While the students in the experimental group received introductory programming education with Math-supported activities, the students in the control group received programming education with traditional course activities. Equivalent programming activities were carried out in both groups. Data were collected via two scales; Computational Thinking Test and Self-Efficacy Perception Scale for Computational Thinking Skills. After the study was completed, post-test scores were analyzed by ANCOVA analysis by controlling pre-test scores. The findings indicated no difference between the two groups regarding computational thinking test performance. Similarly, no conclusion stated a difference between the groups’ perceptions of self-efficacy of computational thinking. According to these results, evaluations regarding the positive and negative effects of using mathematics and programming together in an elementary programming education, which is thought to be related to Computational Thinking Skills, were reached at the skills of the study.
Análise epidemiológica da Leishmaniose na Região Integrada de Desenvolvimento do Distrito Federal e Entorno entre 2016 e 2020
Authors: Ribeiro Gabriella , Portes José , Dantas Lucas
Published: February 2024

Contexto: As leishmanioses constituem um conjunto de enfermidades que podem afetar mucosas e vísceras em seres humanos. Sua incidência tende a manifestar-se em localidades com problemas ambientais e de baixa renda, como áreas desmatadas e com carência de equipamentos de infraestrutura. Isso pode levar ao agravamento da situação imunológica já precária da população em resposta à doença. Metodologia: Este trabalho epidemiológico configura-se como um estudo ecológico, por meio da análise de parâmetros demográficos, dentro do recorte espacial dos entes administrativos que compõem a Região Integrada de Desenvolvimento Econômico do Distrito Federal e Entorno (RIDE-DF), no período de 2016 a 2020. Os dados utilizados foram obtidos no Sistema de Informação de Agravos de Notificação (SINAN). Resultados: A pesquisa identificou um total de 183 casos de LV e 829 casos de LTA referentes a residentes nas 34 unidades administrativas da RIDE-DF, e um total de 203 casos de LV e 798 casos de LTA de notificações realizadas nestes municípios. O perfil dos infectados apresenta predominância de pessoas do sexo masculino, dentro da faixa etária entre 20 e 59 anos,mas com um número considerável de infectados entre a população infantil e idosa. Mecanismos de controle da doença baseados em evidências podem ser melhorados, como a abordagem por meio do modelo One Health e com atuação integrada entre diferentes entes governamentais.
An unusual presentation of small bowel volvulus: A case report
Authors: Almaimani Ghassan
Published: February 2024

Introduction: Small bowel volvulus (SBV) is a surgical emergency that requires prompt diagnosis and treatment. Although sudden onset acute abdominal pain is the most common presenting symptom, the clinical presentation of SBV can be misleading. Early diagnosis and treatment are therefore crucial for a good outcome.

Case Report: A 49-year-old woman presented with a 5-hour history of nausea as her only symptom. Six hours after admission, she developed multiple episodes of vomiting, but without abdominal pain. An urgent CT of the abdomen revealed a pathognomonic “whirl” pattern highly suggestive of SBV, and emergency laparoscopy revealed ileal volvulus without any identifiable pathoetiological factors. She underwent simple devolvulation and made a rapid recovery without recurrence at 12 months.

Conclusion: This case highlights that the preoperative clinical diagnosis of small bowel volvulus can be challenging, emphasizing the importance of preoperative imaging and maintaining a high index of suspicion to avoid missing this important diagnosis. A laparoscopic approach can be used successfully to treat SBV.
Neuroprotective effect of Dark Chocolate on ketamine-induced animal model of psychosis through the reversal of behavioral, biochemical and histopathological changes
Authors: Yadav Monu , Parle Milind , Lamba Deepak , Kumar Sumit , Dahiya Mini , Joshi Kajal
Published: February 2024

The present study was designed to evaluate the antipsychotic-like activity of dark chocolate against Ketamine-induced psychosis in animals and to explore the possible underlying mechanisms for this activity. Dark chocolate (200, 400 mg/kg, along with diet), haloperidol (1mg/kg, i.p.), and olanzapine (5mg/kg, i.p) were administered daily to different groups of mice and rats; after 30 min Ketamine was injected for 21 successive days. The antipsychotic- like activity was assessed using an actophotometer, stereotypic behaviors, forced swim test (FST), and passive avoidance test. Dark Chocolate (DC) and olanzapine remarkably decreased the immobility period of Ketamine-treated mice in FST, indicating the beneficial effect of DC against depressive or negative symptoms of psychosis. There was no significant effect on the locomotor activity of the mice with the administration of DC, while it showed a reducing impact against stereotypic behaviors. Furthermore, DC significantly reduced the time taken by the rats to climb the pole, showing the effect of DC on cognition. In addition, acetylcholinesterase (AChE) activity, malondialdehyde (MDA), and tissue necrosis factor (TNF-α) levels were markedly decreased and increased GABA and enhanced reduced glutathione (GSH) levels with the treatment of DC. Furthermore, DC was also effective in reducing the ketamine induced hyperchromatic nuclei, perinuclear vacuolization, and dilated vascular channels in the cortex part of the brain. Behavioral, biochemical, and histopathological studies suggest the protective effect of DC against Ketamine induced psychosis.
Phytoremediation- Friendlier and Affordable Approach to Remediate Heavy Metal Pollution
Authors: Ghosh Shirshendu , Ghosh Bidisha , Ghosh Mouli , Paul Shouvik , Pal Ankit , Dey Trina , Sarkar Subhasis , Ghosh Semanti , Ghosh Bidisha , Sarkar Suranjana
Published: February 2024

Water and soil contamination is currently one of the world's most serious problems. Various heavy metals such as zinc, arsenic, mercury, cadmium, and copper dissolve in water, causing a variety of health problems such as cardiovascular illnesses, kidney damage, and the risk of death in diabetic and cancer patients. Soil pollution can also reduce crop yields, affecting the food chain and economy. Different physical and chemical procedures for soil and waste water treatment are available; however they are insufficient in terms of cost and availability. But wouldn't it be wonderful if we could instead use nature to aid nature? "Phytoremediation," a technique in which plants absorb heavy metals from soil and waste water as a nutrient and purify the medium, is the greatest natural remedy for treating this problem. Since the 1990s, it has been an extensively employed approach. The damaging consequences of heavy metals in living systems are discussed in this article, as well as the function of phytoremediation in treating this problem, future possibilities and challenges.
WATER RECLAMATION THROUGH NANOREMEDIATION & BIOREMEDIATION: A WEAL AGAINST CONVENTIONAL CHEMICAL TECHNIQUES
Authors: Pal Nisha , Das Parthita , Dutta Rittick , Sarkar Sany , Mukherjee Shreshtha , Devi Pragyasini , Mukherjee Moumita , Dhar Samrat , Ghosh Semanti , Sarkar Suranjana , Sarkar Subhasis , Ghosh Bidisha
Published: February 2024

Worldwide unprecedented challenge has been posed due to socio- economical-demographic and environmental transitions. These threats mainly sprout from rapid pace in modernization and advancement of technologies for economic escalation and raising live standards. These however is a bane since over the years there are instances of loss of considerable biodiversity, risks in public health, aggravation of already existing health issues, decline of soil salinity and to add to the plight there is water scarcity that mainly had resulted due to imbalance in the potable water available and its demand. Climate change, indiscriminate efflux of contaminants encompassing household to industrial waste water has profound effects on the standards of water quality. To cope with this situation there should be judicious planning leading to recycling the waste water in a more convenient way over prevalent robust technologies. The focus lies on the participation of nano-based materials that have been revered highly for their large surface to volume ratio and are efficient candidates for solid waste recovery. Nanomaterials both metallic non-metallic and polymeric materials have been the subject of interest for their diligent participation as catalyst, nano sorbents. Besides the participation of natural materials and benevolent biological components in bioremediation of waste water has been discussed herein.
Structural And Functional Relationship Study In Plant Salinity Stress
Authors: Chakraborty Bipasha , Gosai Rajiv , Saha Deep , Nayek Biswajit , Biswas Piyasha , Gupta Abhimanyu Das , Ghosh Riya , Ghosh Bidisha , Sarkar Subhasis , Sarkar Suranjana , Ghosh Semanti
Published: February 2024

In today’s world the increased use of low-quality water for irrigation and soil salinization, saltness is a huge biotic problem that effecting factory growth and product in numerous corridors in the world. In repercussion to salt stress, plant cells accumulate compatible solutes and redistribute ions, all of which contribute them to acclimate to a low soil water potential. In addition, the endogenous abscisic acid (ABA) content increases daily, followed by changes in principle genetic expression in salt stress conditions. Here we are going to discuss about the proteins involved in plant salinity stress and their interactions with the salt tolerant factor which has a negative impact with the plant growth system. Some highly evaluated proteins that were observed under this stress are Plant ferredoxin-like protein (PFLP), Arabidopsis thaliana Salt Tolerance Related Protein (STRP), OsEXPA7, ribulose-1, 5-bisphosphate carboxylase (RuBP), etc. This report is also going to focus on various transcription factors (tf), responsible for the enhanced tolerance under biological activity of plant development. TFs bZIP, MYBs, bHLH, C2H2-Dof, G2-like, AP2-EREBP, NAC, GATA, ARF, ERF, bZIP and MYB which were highly up- regulated in salt stress response.
Acute Kidney Injury in Adults due to COVID-19 infection: A Systematic Review and Meta-Analysis
Authors: Koley Snehashis , Bose Ambar , Mukherjee Mandira
Published: February 2024

Background: In COVID-19 infection, Acute Kidney Injury (AKI) poses a severe complication. To help clinicians to implement effective clinical therapy, we systematically documented evidence on AKI incidence and associated death in COVID-19 infection among adult populations. Methods: For the systematic review and meta-analysis Guidelines laid by Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) were followed. Studies were searched from Pubmed and MedRxiv databases published between December 2019 - June 19, 2021. Results: 55 out of 3175 total articles were identified as eligible for the qualitative review with 32 reports on adults (n=169560); mean age 65.34 years. Studies on AKI incidence, mortality, and AKI-related mortality in COVID-19-infected adults p were included in the meta-analysis. Estimated AKI incidence in adults was 16.4% ([95%CI, 12.8 – 20.0%], I2 =99.39%, P<0.001). Moreover, overall death 34.8% ([95%CI, 21.3- 48.3%], I2 = 99.88%, P<0.001) and AKI-related death 68.4% ([95%CI, 55.9–81.0%], I2=99.2%, P<0.001) among adults revealed high statistical heterogeneity. Conclusion: AKI- related mortality was significantly high in COVID-19-infected adults. Therefore, AKI is common in COVID-19 infection and clinical management must be accordingly formulated.
Ethyl Methanesulfonate (EMS)-Mediated Fruit Mutants Of Bitter Gourd (Meghna-2): A Popular Landrace Of West Bengal
Authors: Salma Umme , Giri Debadrita , Sinha Mohit Kumar , Kundu Suprabuddha
Published: February 2024

Ethyl methanesulfonate (EMS) is a stable and effective chemical mutagen. Bitter Gourd (Meghna-2) seeds were treated by 0.3, 0.5, and 1% EMS for 24 h and 48 h to optimize EMS mutagenesis. Median lethal dose of EMS was obtained at 0.3% EMS treated for 48 h. After treated by 0.3% EMS for 48 h, 250 M1 plants were grown in field for phenotype determination. In comparison to the control, a decline in germination, leaf shape, fruit size, fruit shape, vine length, and emergence was seen in the M1 generation when the concentration of applied EMS was increased. The fertility of M1 bitter gourd was very low and only 24 lines produced seeds after self crossing. Of the mutant 24 lines in the plant growth, five were dwarf, two were tall, four had retarded fruit size, and 13 had abnormal branching and flowering. Only four lines (G 6, G 9, G 14 and G 15) raised from M2 generations of Meghna-2, were screened critically and observed no significant reduction in seed germination and pollen viability but the fruit size was significantly decreased. Interestingly, the short fruit type and round shape of Meghna-2 (G 9) was chosen amongst the four due to farmer’s acceptability, which was grown further to confirm the stability.
Luffa Cylindrica (L.) As Potential Foraging Source For Insect Pollinators During Post Monsoon Season – A Study In Gangetic Plain Of West Bengal
Authors: Das Rakesh , Layek Amit , Nandi Tripti , Jha Shantanu
Published: February 2024

Pollination is an important ecosystem service and insects play the most vital role of its. Insect pollinators need good foraging resources all year long to survive, which are provided by both wild and cultivated plants. However, although being crucial for pollinator survival during scarcity, these wild plants receive little attention. Present study had been carried out in Gangetic plain of West Bengal to document the potentiality of the wild creeping plant, Luffa cylindrica L. as foraging resource for insect pollinators during the post monsoon season, when flowering in major trees is sparse. Active netting explore diversity of flower visitors, while palynological study confirms the pollen foraging activity of two reared honey bees, Apis mellifera L. and Apis cerana indica F. on the creeper. Insects belonged to orders viz. Hymenoptera, Diptera, Lepidoptera and Coleoptera were found to visit. Hymenopterans were the major insect visitors comprising 66.34% of total. Palynological study revealed that Apis mellifera and Apis cerana indica togetherly visit 17 and 16 plant species for pollen collection during the study months. In October, Luffa cylindrica contributed 10.53% and 11.27% of total pollen taxa foraged by Apis mellifera and Apis cerana indica respectively and grouped as important minor pollen for the honey bees. However, in the month of November it contributed 11.84% and 9.88% of total respectively. Being a creeper, however, these are not given much protection and are often weeded out, which can have a negative impact on native pollinator populations foraging on the crops.
แนวทางการบริหารรถสวัสดิการกองทัพเรือเส้นทางท่าราชวรดิฐ-ฐานทัพเรือสัตหีบ จังหวัดชลบุรี ในสถานการณ์วิกฤตโควิด-19
Authors: ศรีทัศน์ พงศกร , แก้วธรรมชัย เรืองศักดิ์
Published: February 2024

การวิจัยนี้มีวัตถุประสงค์เพื่อ 1) ศึกษาอิทธิพลของแนวทางการบริหารรถสวัสดิการกองทัพเรือเส้นทาง   ท่าราชวรดิฐ ฐานทัพเรือสัตหีบในสถานการณ์วิกฤตโควิด-19 ที่มีต่อความคาดหวังการบริการ และ 2) ศึกษาและเสนอแนวทางการบริหารรถสวัสดิการกองทัพเรือเส้นทางท่าราชวรดิฐ   ใช้รูปแบบการวิจัยแบบวิจัยแบบผสม รวบรวมข้อมูลเชิงปริมาณด้วยแบบสอบถาม 233 ตัวอย่าง และวิธีเชิงคุณภาพสัมภาษณ์เชิงลึก 12 คน ใช้การวิเคราะห์ข้อมูลโดยใช้สถิติเชิงพรรณนาและทดสอบสมมติฐานการวิจัยด้วยการวิเคราะห์ความถดถอยเชิงพหุคูณ  ผลการวิจัยพบว่า  1) บริหารรถสวัสดิการกองทัพเรือเส้นทางท่าราชวรดิฐ ฐานทัพเรือสัตหีบในสถานการณ์วิกฤต   โควิด-19  มีอิทธิพลต่อความคาดหวังการ ทั้งนี้ ตัวแปรต้นที่มีอำนาจพยากรณ์ดีที่สุด คือ การบริหารรถสวัสดิการ  และ 2) แนวทางการบริหารรถสวัสดิการกองทัพเรือเส้นทางท่าราชวรดิฐ ฐานทัพเรือ สัตหีบ พบว่า  (1) จะต้องจำกัดจำนวนผู้โดยสารที่ใช้บริการไม่เกิน 75% ของความจุผู้โดยสาร เช่น รถทัวร์ 1 คันจุได้ 60 คน ในช่วงโควิด-19 จะรับผู้โดยสารได้เพียง (75%) จุได้เพียง 45 คน (2) จะต้องแจ้งข้อมูลข่าวสารเกี่ยวกับการเดินรถให้ผู้โดยสารรับรู้ได้ถึงการปรับเปลี่ยนการให้บริการที่ต่างไปจากเดิม  และ (3) จะต้องยังคงเปิดให้บริการได้แม้จะอยู่ในช่วงสถานการณ์โควิด-19 ไม่ปิดบริการเนื่องจากผู้โดยสารจะเดือดร้อน  ดังนั้น  ผู้บริหารรถสวัสดิการกองทัพเรือ จะต้องยังคงเปิดให้บริการได้ในช่วงสถานการณ์โควิด-19 และเข้มงวดในการบริการรถเพื่อความปลอดภัยและยังคงรักษาระดับการให้บริการที่ดี