bluuebunny/crossref_metadata_2025 huggingface dataset:
Eight-Week Pilates or Whole-Body High-Intensity Interval Training Program Improves Spinal Range of Motion During the Gait Cycle in Sedentary Women: A Preliminary Study
Authors: Gonçalves Sabrina Fernandes , do Vale Arthur Ferreira , La Scala Teixeira Cauê Vazquez , de Oliveira Joyce Sousa , Vitória Jordana Rodrigues , Carneiro Juliana Alves , Campos Mário Hebling
Published: January 2025

This study aimed to compare the effects of Pilates (PIL) and whole-body high-intensity interval training (WBHIIT) on the spinal curvature of sedentary women. After being invited, 26 sedentary women aged between 20 and 54 voluntarily agreed to participate in the study. The sample was obtained through convenience sampling, and the participants chose either PIL or WBHIIT, which resulted in 13 participants in each group. Spinal posture was assessed pre- and post-intervention through videogrammetry during standing and walking. Markers were placed on the back, and the volunteers were instructed to remain in a standing position on a stationary treadmill for ten seconds. Subsequently, the treadmill was activated at a speed of 5 km/h. After one minute of walking, a complete gait cycle was recorded for analysis. The results showed no significant changes in spinal angles in static position between groups. However, in the walking position, there was a large-magnitude increase in the spinal range of motion (ROM) post-intervention (PIL Lumbar d = 1.8; PIL Thoracic d = 2.9; WBHIIT Lumbar d = 1.0; WBHIIT Thoracic d = 3.5) within groups in the sagittal plane. The adaptations promoted by these interventions in spinal ROM are important for reducing the risks of spinal stiffness and pain due to sedentary behaviour.
Predictors of Life Satisfaction in Native Hawaiian and Pacific Islander College Students
Authors: McLellan Kate , Ganzorigta Narantsatsral , Davaakhuu Khulan , Spencer Nicolas
Published: January 2025

This study examines predictors of life satisfaction in Native Hawaiian and Pacific Islander (NH/PI) college students, who form an underrepresented group in well-being research. In a sample of 128 NH/PI students from a public university in Hawaii, self-report measures of life satisfaction, affect, stress, and mood were analyzed. The results indicate that positive affect and mood are significant positive predictors for life satisfaction, while negative affect predicts lower satisfaction. By contrast with other racial/ethnic groups, perceived stress did not significantly impact life satisfaction in NH/PI students. These findings suggest that emotional well-being is a key determinant for life satisfaction in NH/PI students, and stress is not. Culturally responsive interventions that focus on positive emotions and community support can enhance well-being and academic success in this population. This study contributes to the understanding of unique cultural influences on well-being in NH/PI students and provides implications for targeted interventions.
SARS-CoV-2 Infection and the Risk of New Chronic Conditions: Insights from a Longitudinal Population-Based Study
Authors: De Ridder David , Uppal Anshu , Rouzinov Serguei , Lamour Julien , Zaballa María-Eugenia , Baysson Hélène , Joost Stéphane , Stringhini Silvia , Guessous Idris , Nehme Mayssam
Published: January 2025

Background: The post-acute impact of SARS-CoV-2 infections on chronic conditions remains poorly understood, particularly in general populations. Objectives: Our primary aim was to assess the association between SARS-CoV-2 infections and new diagnoses of chronic conditions. Our two secondary aims were to explore geographic variations in this association and to assess the association between SARS-CoV-2 infections and the exacerbation of pre-existing conditions. Methods: This longitudinal study used data from 8086 participants of the Specchio-COVID-19 cohort in the canton of Geneva, Switzerland (2021–2023). Mixed-effects logistic regressions and geographically weighted regressions adjusted for sociodemographic, socioeconomic, and healthcare access covariates were used to analyze self-reported SARS-CoV-2 infections, new diagnoses of chronic conditions, and the exacerbation of pre-existing ones. Results: Participants reporting a SARS-CoV-2 infection were more likely to be diagnosed with a new chronic condition compared to those who did not report an infection (adjusted odds ratio [aOR] = 2.15, 95% CI 1.43–3.23, adjusted p-value = 0.002). Notable geographic variations were identified in the association between SARS-CoV-2 infections and new diagnoses. While a positive association was initially observed between SARS-CoV-2 infections and exacerbation of pre-existing chronic conditions, this association did not remain significant after adjusting p-values for multiple comparisons. Conclusions: These findings contribute to understanding COVID-19’s post-acute impact on chronic conditions, highlighting the need for targeted health management approaches and calling for tailored public health strategies to address the pandemic’s long-term effects.
A Conceptual Model of Refugee Family Dynamics: A Study with Sri Lankan Tamils
Authors: Kuttikat Miriam , Lund Marianne B. , Chan David , Sahoo Indranil
Published: January 2025

Sri Lankan Tamil refugees have endured over four decades of protracted displacement in southern India. This paper synthesizes findings from four studies conducted between 2005 and 2018 among refugees residing in the Gummidipoondi and Trichy refugee camps in the state of Tamil Nadu, India. Framed by a Community Based Participatory Research, in collaboration with the Organization for Eelam Refugee Rehabilitation (OfERR) and Community Advisory Board, these studies aimed to investigate the challenges related to migration stressors, mental health, family dynamics, and resource utilization of the Sri Lankan refugees living in India. The association of Psychological Distress and Migration Stress (PDMS) study examined migration stressors influencing psychological distress among refugees. The intergenerational Conflict and Community Readiness (ICCR study) assessed community readiness for repatriation and intergenerational conflict employing semi-structured qualitative interviews. The Family Dynamics (FD) mixed-method study investigated longitudinal associations between migration stressors, resource utilization, family dynamics, and health outcomes among Sri Lankan Tamil refugees. The Parenting Processes and Intervention Development (PPID) Study incorporated perspectives of community health workers through qualitative exploratory research. Integrating these findings, the research developed (1) Conceptual Model of Refugee Family Dynamics and (2) Framework for Refugee Health Intervention. These models provide a culturally sensitive framework for future interventions to improve family well-being among refugee populations.
Adolescents with Normal Weight Obesity Have Less Dry Lean Mass Compared to Obese Counterparts
Authors: Brown Ann F. , Aguiar Bonfim Cruz Ariel J. , Schwartz Malayna G. , Brooks Samantha J. , Chandler Alexa J.
Published: January 2025

Normal weight obesity (NWO) is a condition characterized by a normal body mass index (BMI; 18.5–24.9 kg·m−2) yet excess body fat. Those with this condition have an increased risk of cardiometabolic diseases associated with obesity. The prevalence of NWO is not well investigated in adolescents, particularly in the United States. This study examined the prevalence of NWO and dietary behaviors among adolescents aged 14–19 years old (n = 139) who live in a rural area in the United States. Data were collected from December 2019 through February 2020. Body composition was assessed via bioelectrical impedance analysis and diet was assessed using an Automated Self-Administered 24 h food recall questionnaire. Participants were categorized by BMI and body fat percentage as NWO, normal weight lean (NWL), or obese (OB). The sample prevalence of NWO was 13.6%, with girls having a higher prevalence (22.2%) than boys (1.8%). Those with NWO had significantly lower dry lean mass than OB (p = 0.02), but there were no differences between NWL and OB (p = 0.08). There was significantly higher caloric intake (p = 0.02) among NWL compared to OB, and NWL consumed more fiber than both NWO (p = 0.02) and OB (p = 0.03). Overall, this study gives us a better understanding of the prevalence of NWO in the adolescent population and the dietary habits associated with each group. Those with NWO may be at increased risk for negative long-term health outcomes commonly associated with obesity. Additionally, the higher caloric intake among NWL was unexpected and should be investigated further.
A Real-World Study on the Quality of Life of Consumers with Dentine Hypersensitivity and the Benefits of Hypersensitivity Toothpaste Use
Authors: Tadjoedin Fatimah Maria , Soeroso Yuniarti , Widaryono Adityo , Haerani Natalina , Lee Yun Yee Amber , Parkinson Charles R. , Tan Sheryl S. L. , Gadzhieva-Moore Aida , Tan Rachel Lee-Yin , Garg Vandana
Published: January 2025

Dentine hypersensitivity (DH) causes pain from exposed dentine, triggered by external stimuli. Limited evidence exists on its impact on quality of life (QoL), the effectiveness of hypersensitivity toothpaste (HT) and the dental behaviors of DH sufferers. This study therefore aimed to generate evidence to address these evidence gaps and validate the existing science behind the effectiveness of HT. An observational retrospective cross-sectional survey was conducted in Indonesia, which included the Dentine Hypersensitivity Experience Questionnaire-15 (DHEQ-15), items related to the perceived effectiveness of HT and self-reported dental health behaviors. A total of 511 respondents completed the survey. The mean (standard deviation) DHEQ score of participants was 82.44 (14.41), showing the substantial impact of DH on QoL. Nearly all HT users (97.7%) reported relief from DH, with additional benefits like long-lasting fresh breath (96.4%) and cleaner teeth (97.1%), with regular HT users experiencing greater benefits such as improvements in DH (R-HT users [4.65 (0.55)] vs. E-HT users [4.46 (0.65)], p < 0.01). Compared to HT users, mainstream toothpaste (MT) users were significantly less likely to brush their teeth at least three times a day (HT users [41.9%], MT users [18.7%], p < 0.05) and to have had a dental check-up within the past year (HT users [82.5%], MT users [47.3%], p < 0.05). This study found that DH significantly impacts QoL, and that HT effectively relieves DH symptoms, particularly for regular users, who also show better dental health behaviors than users of mainstream toothpaste. The preliminary results indicate that educating users about dental products, like hypersensitivity toothpaste, can improve oral health behaviors and outcomes.
Spatial Dynamics and Drivers of Urban Growth in Thua Thien Hue Province, Vietnam: Insights for Urban Sustainability in the Global South
Authors: Obaitor Olabisi S. , Odunsi Oluwafemi Michael , Vu Thanh Bien , Grobusch Lena C. , Schultz Michael , Hochschild Volker , Khanh Linh Nguyen Hoang , Garschagen Matthias
Published: January 2025

Investigating the historical patterns of urban growth and their drivers is crucial to informing sustainable urban planning policies, especially in cities of the Global South. In Vietnam, most studies focus primarily on city extents, offering little insight into urban growth across various provinces. This study, therefore, combined categorical land use and land cover change detection, Random Forest classification and expert interviews to quantify the urban growth between 2000 and 2020, assess urban encroachment upon other land uses, and identify key drivers shaping this growth in Thua Thien Hue province. Findings show that the urban land areas were 27.94 km2, 82.97 km2, and 209.80 km2 in 2000, 2010, and 2020, respectively. Urban encroachment upon other land use types, especially cropland, barren land, rice paddies, shrubs, and forests, was observed in these periods. Additionally, accessibility to built-up areas, DEM, proximity to rice paddies, slope, proximity to street roads, accessibility to social areas, and proximity to cropland are the major spatial drivers of urban growth in the province. The study concludes that rapid urban expansion is evident in the province at the expense of other land use types, especially agricultural land use types, which may impact food security and livelihoods in the province.
The Role of Myokines in Liver Diseases
Authors: Nishikawa Hiroki , Kim Soo Ki , Asai Akira
Published: January 2025

Myokine is a general term for hormones, peptides, and other substances secreted by skeletal muscle. Myokine has attracted much attention in recent years as a key substance for understanding the mechanism of “exercise and health”. Skeletal muscle accounts for about 40% of the total human weight and is now recognized as an endocrine organ that produces myokines, which have physiological activity. Representative myokines include IL-6, myostatin, irisin, brain-derived neurotropic factor, fibroblast growth factor-21, and decorin. On the other hand, sarcopenia, defined by quantitative and qualitative loss of skeletal muscle, is a condition that has received much attention in recent years because of its close correlation with prognosis. In patients with chronic liver disease (CLD), sarcopenia is a common complication. Mechanisms underlying sarcopenia in CLD patients have been reported to involve protein-energy malnutrition, which is characteristic of patients with cirrhosis, signaling involved in protein synthesis and degradation, myokines such as myostatin and decorin, the ubiquitin-proteasome pathway, sex hormones such as testosterone, dysbiosis, and insulin resistance, etc., in addition to aging. Each of these pathological conditions is thought to be intricately related to each other, leading to sarcopenia. This review will summarize the relationship between CLD and myokines.
Anthocyanins in Black Soybean Coats Promote Apoptosis in Hepatocellular Carcinoma Cells by Regulating the JAK2/STAT3 Pathway
Authors: Li Yuying , Wang Miaomiao , Bai Jinjing , Li Xin , Xiao Sheng , Song Li
Published: January 2025

The use of black soybean (Glycine max L.), an edible crop prevalent in Asia, has attracted attention for its hepatoprotective properties. Notably, the anthocyanin components in black soybean coats have shown potential in inhibiting tumor growth. Here, anthocyanins were extracted from black soybean coats using both microwave and water bath methods. The physicochemical characteristics of black soybean coat anthocyanins (BSCAs) and their biological activities were examined. The results from the MTT and EDU assays demonstrated a dose-dependent inhibitory effect of BSCAs on hepatocellular carcinoma HepG2 cells, while leaving normal cells unaffected. Flow cytometry and mitochondrial membrane potential assays revealed that BSCA treatment induces apoptosis in HepG2 cells. A network pharmacology approach was employed to explore the relationship between hepatocellular carcinoma and the active ingredients of BSCAs, identifying the JAK/STAT signaling pathway as a potential target. Molecular docking studies confirmed the interaction between BSCA components and JAK2/STAT3 targets. Subsequent Western blot and qPCR experiments validated that BSCAs promote apoptosis in HepG2 cells by modulating the JAK2/STAT3 signaling pathway.
Elastomeric Biocomposites of Natural Rubber Containing Biosynthesized Zinc Oxide
Authors: Sowińska-Baranowska Anna , Maciejewska Magdalena
Published: January 2025

Zinc oxide (ZnO) particles were successfully synthesized through the green method using aloe vera extract and zinc nitrate (1:1). The structure, morphology and properties of the biosynthesized ZnO (bioZnO) particles were analyzed by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), time of flight secondary ion mass spectrometry (TOF-SIMS) and thermogravimetry (TG). The morphology and the size of ZnO particles were elucidated by scanning electron microscopy (SEM) with energy-dispersive X-ray spectroscopy (EDS). Then, the ability of bioZnO to activate sulfur curing of natural rubber (NR) was tested and compared to commercial ZnO traditionally used as vulcanization activator. The bioZnO showed similar activity in the vulcanization process to commercial ZnO. NR composites containing bioZnO were pro-ecological in nature and exhibited better mechanical characteristics and durability against thermo-oxidative aging than NR with commonly used micrometric ZnO. Moreover, NR vulcanizates containing bioZnO showed good mechanical properties in dynamic conditions and satisfactory thermal stability. The present research is new and in addition to the analysis of biosynthesized ZnO particles, the effect of the activator in the vulcanization process of the NR elastomer and its influence on the properties of the final products were additionally discussed.
Diagnosis and Management of Hypertensive Heart Disease: Incorporating 2023 European Society of Hypertension and 2024 European Society of Cardiology Guideline Updates
Authors: Wang Brian Xiangzhi
Published: January 2025

Hypertensive heart disease (HHD) continues to be a leading cause of cardiovascular morbidity and mortality worldwide, necessitating the evolution of evidence-based management strategies. This literature review examines the most recent updates from the 2023 and 2024 hypertension guidelines issued by the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC). These guidelines are compared with previous key recommendations, such as the 2017 American College of Cardiology/American Heart Association guidelines and the 2018 ESC/ESH guidelines. The updated recommendations reflect a paradigm shift in the approach to hypertension diagnosis and management, including a stricter systolic blood pressure (BP) target of 120–129 mmHg, which underscores the importance of early and precise BP control. The difference between the classification of “elevated BP” and hypertension in the ESC versus ESH guidelines, particularly, regarding their implications for early detection and prevention of HHD, are critically examined, highlighting areas of clinical and academic debate. The introduction of a new “elevated BP” category (120–139/70–89 mmHg) highlights a proactive strategy aimed at identifying at-risk individuals earlier in the disease course to prevent progression to HHD. Additionally, the divergent roles of hypertension-mediated organ damage (HMOD), including HHD, in risk stratification as recommended by the ESC and ESH are discussed, emphasising their significance in tailoring management approaches. For patients with resistant hypertension, the 2023 and 2024 updates also endorse innovative therapies, such as renal denervation, an interventional procedure that has demonstrated significant promise in managing treatment-resistant cases. This review synthesises these updates, focusing on their implications for clinical practice in diagnosing and managing HHD. By emphasising aggressive intervention and the integration of novel treatment modalities, the review aims to bridge existing gaps in earlier approaches to hypertension management. The critical evaluation of guideline discrepancies and evolving evidence seeks to provide clinicians with a nuanced understanding to optimise outcomes for patients with HHD, particularly considering emerging therapeutic possibilities and more stringent BP control targets.
Optimization of the Properties of Eco-Concrete Dispersedly Reinforced with Hemp and Flax Natural Fibers
Authors: Beskopylny Alexey N. , Shcherban’ Evgenii M. , Stel’makh Sergei A. , Chernilnik Andrei , Elshaeva Diana , Ananova Oxana , Mailyan Liya D. , Muradyan Viktor A.
Published: January 2025

Dispersed reinforcement of concrete with various types of plant fibers is currently a fairly popular area in the field of construction materials science. The relevance of this topic is determined by the fact that the issue has not been studied on a large scale in comparison with concrete reinforced with artificial fibers, and the fact that these types of concrete meet the requirements of the Sustainable Development Goals. The purpose of this work was to evaluate the efficiency of using hemp fiber (HF) and flax fiber (FF) for the dispersed reinforcement of concrete, and to compare their efficiency and practical applicability in the construction industry. Before use, HF and FF were treated with a NaOH solution and stearic acid to increase their resistance to the aggressive alkaline environment of concrete. A total of 15 concrete compositions were made. The percentage of dispersed reinforcement for both types of fibers varied from 0.2% to 1.4%, with a step of 0.2%. The standard methods of mechanical testing and microscopy for investigation the properties of fresh and hardened concrete were applied. The optimum amount of HF in concrete was 0.6%, which provided an increase in compressive and flexural strength of 7.46% and 28.68%, respectively, and a decrease in water absorption of 13.58%. The optimum percentage of FF concrete reinforcement was 0.8%, which allowed an increase in compressive and flexural strength of 4.90% and 15.99%, respectively, and a decrease in water absorption of 10.23%. The results obtained during the experiment prove the possibility and effectiveness of the practical application of hemp and flax fibers in concrete composite technology.
Distributed Consensus Gossip-Based Data Fusion for Suppressing Incorrect Sensor Readings in Wireless Sensor Networks
Authors: Kenyeres Martin , Kenyeres Jozef , Hassankhani Dolatabadi Sepideh
Published: January 2025

Incorrect sensor readings can cause serious problems in Wireless Sensor Networks (WSNs), potentially disrupting the operation of the entire system. As shown in the literature, they can arise from various reasons; therefore, addressing this issue has been a significant challenge for the scientific community over the past few decades. In this paper, we examine the applicability of seven distributed consensus gossip-based algorithms for sensor fusion (namely, the Randomized Gossip algorithm, the Geographic Gossip algorithm, three initial configurations of the Broadcast Gossip algorithm, the Push-Sum protocol, and the Push-Pull protocol) to compensate for incorrect data in WSNs. More specifically, we consider a scenario where the sensor-measured data (measured by a set of independent sensor nodes) are skewed due to Gaussian noise with a various standard deviation σ, resulting in discrepancies between the measured values and the true value of observed physical quantities. Subsequently, the aforementioned algorithms are employed to mitigate this skewness in order to improve the accuracy of the measured data. In this paper, WSNs are modeled as random geometric graphs with various connectivity, and the performance of the algorithms is evaluated using two metrics (specifically, the mean square error (MSE) and the number of sent messages required for an algorithm to be completed). Based on the presented results, it is identified that all the examined algorithms can significantly suppress incorrect sensor readings (MSE without sensor fusion = −0.42 dB if σ = 1, and MSE without sensor fusion = 14.05 dB if σ = 5), and the best performance is achieved by PS in dense graphs and by GG in sparse graphs (both algorithms achieve the maximum precision MSE = −24.87 dB if σ = 1 and MSE = −21.02 dB if σ = 5). Additionally, the performance of the analyzed distributed consensus gossip algorithms is compared to the best deterministic consensus algorithm applied for the same purpose.
Effect of Seabed Type on Image Segmentation of an Underwater Object Obtained from a Side Scan Sonar Using a Deep Learning Approach
Authors: Park Jungyong , Bae Ho Seuk
Published: January 2025

This study examines the impact of seabed conditions on image segmentation for seabed target images acquired via side-scan sonar during sea experiments. The dataset comprised cylindrical target images overlying on two seabed types, mud and sand, categorized accordingly. The deep learning algorithm (U-NET) was utilized for image segmentation. The analysis focused on two key factors influencing segmentation performance: the weighting method of the cross-entropy loss function and the combination of datasets categorized by seabed type for training, validation, and testing. The results revealed three key findings. First, applying equal weights to the loss function yielded better segmentation performance compared to pixel-frequency-based weighting. This improvement is indicated by Intersection over Union (IoU) for the highlight class in dataset 2 (0.41 compared to 0.37). Second, images from the mud area were easier to segment than those from the sand area. This was due to the clearer intensity contrast between the target highlight and background. This difference is indicated by the IoU for the highlight class (0.63 compared to 0.41). Finally, a network trained on a combined dataset from both seabed types improved segmentation performance. This improvement was observed in challenging conditions, such as sand areas. In comparison, a network trained on a single-seabed dataset showed lower performance. The IoU values for the highlight class in sand area images are as follows: 0.34 for training on mud, 0.41 for training on sand, and 0.45 for training on both.
The Global Integration Dilemma: Functionalist Efficient Stability Versus Geoeconomic Vulnerability Risks
Authors: Aligica Paul Dragos , Ciobanu Robert Gabriel
Published: January 2025

This article explores the complex trade-offs involved in global economic integration. While economic integration, through mechanisms such as customs unions, promotes efficiency, trade, and cooperation, it also introduces significant vulnerabilities, particularly in the context of geoeconomics and weaponized interdependence. Drawing on the theories of Jacob Viner and David Mitrany, this paper illustrates how functionalist economic stability and efficiency are essential but must be balanced with considerations of resilience and security. Case studies such as the COVID-19 pandemic and Europe’s reliance on Russian gas during the Ukraine war highlight the risks of overdependence in interconnected global systems. Ultimately, this paper argues for a nuanced approach that balances economic benefits with the geopolitical risks of interdependence, advocating for a mixed framework that integrates both efficiency and stability.
Macrovascular Function in People with HIV After Recent SARS-CoV-2 Infection
Authors: Salazar Ana S. , Vincent Louis , Ebner Bertrand , Fonseca Nogueira Nicholas , Krauss Leah , Meyer Madison S. , Grant Jelani , Aguilar Natalie , Pester Mollie S. , Parker Meela , Gonzalez Alex , Mendez Armando , Carrico Adam , Hurwitz Barry E. , Alcaide Maria L. , Martinez Claudia
Published: January 2025

Background: People with HIV (PWH) are at increased risk of vascular dysfunction and cardiovascular disease (CVD). SARS-CoV-2 infection has been associated with acute CVD complications. The aim of the study was to as-sess macrovascular function as an early indicator of CVD risk in PWH after mild SARS-CoV-2 infection. Methods: PWH aged 20–60 years, with undetectable viral load (RNA < 20 copies/mL), on stable anti-retroviral therapy (≥6 months) and history of mild COVID-19 (≥30 days) without any CVD manifestations prior to enrollment were recruited. Participants were excluded if they had history of diabetes mellitus, end-stage renal disease, heart or respiratory disease. Participants were matched 1:1 to pre-pandemic PWH. A health survey, surrogate measures of CVD risk, and macrovascular function (brachial artery flow-mediated vasodilation and arterial stiffness assessments via applanation tonometry) were compared between group. Results: A total of 17 PWH and history of COVID-19 (PWH/COV+) were matched with 17 PWH without COVID-19 (PWH/COV−) pre-pandemic. Mean age (45.5 years), sex (76.5% male), body mass index (27.3), and duration of HIV infection (12.2 years) were not different between groups. Both groups had comparable CVD risk factors (total cholesterol, LDL, HDL, systolic and diastolic blood pressure). There were no differences in measures of flow mediated arterial dilatation or arterial stiffness after 30 days of SARS-CoV-2 infection. Conclusions: After recent SARS-CoV-2 infection, PWH did not demonstrate evidence of macrovascular dysfunction and increased CVD risk. Results suggest that CVD risk may not be increased in people with well-controlled HIV who did not manifest CVD complications SARS-CoV-2 infection.
Quantitative Simulation and Planning for the Heat Island Mitigation Effect in Sponge City Planning: A Case Study of Chengdu, China
Authors: Yang Qingjuan , Lin Ziqi , Li Qiaozi
Published: January 2025

The implementation of sponge cities in China modifies the hydrological conditions of the underlying surface, effectively alleviating the urban heat island effect. However, in planning and construction, heat island mitigation targets are difficult to quantify and lack quantitative design and evaluation methods. To address this issue, two planning schemes were proposed based on sponge city management and control indicators. The WRF-UCM model was used to conduct numerical simulations of the current conditions (case 1) and the sponge city planning schemes (cases 2 and 3), analyzing the impact of sponge city initiatives on the mitigation of the heat island effect. The results indicated that by changing the structure of the underlying surface and increasing the water content of the underlying surface, the sponge city affects the urban energy distribution process and regional horizontal advection pattern. This not only reduces heat accumulation within the urban area but also suppresses regional convection during high-temperature periods, thereby mitigating the urban heat island effect. Moreover, different schemes following the same sponge city design requirements have varying impacts on urban microclimate elements and heat island distributions. Notably, a higher subsurface water content yields a more pronounced inhibition of the heat island effect. Finally, a sponge city planning method with the consideration of heat island mitigation was proposed, facilitating pre-simulation optimization and decision-making in sponge city planning.
Public Value in Historic Environment Regeneration in China: A Public Perception Perspective on Spatial Form, Urban Governance, and People’s Experience (2000–2020)
Authors: Zhang Ruijie , Martí Casanovas Miquel , Bosch González Montserrat , Sun Sijie
Published: January 2025

This study, grounded in the theory of public value, explores how spatial form, urban governance, and people’s experiences influence the realization of public value in the regeneration of historic environments (HER) in China. Addressing the current dilemma faced by historic districts between “destructive construction” and “frozen preservation”, this research proposes that integrating public value into the HER process is crucial for promoting sustainable urban development. This study reviews key theories of public value and critically evaluates their application in historic environment regeneration. From a public perception perspective, this study constructs a hexagon public value model encompassing intrinsic, instrumental, and institutional values, analyzed through the dimensions of spatial form, urban governance, and people’s experiences. Through an empirical analysis of five case studies in China (Chengdu Kuanzhai Alley, Shanghai Tianzifang Alley, Guangzhou Enning Road, Beijing Nanluogu Alley, and Taiyuan Zhonglou Street), this research employs structural equation modeling (SEM) to examine the interactions between these factors. The results reveal that spatial form has a significant positive impact on intrinsic value, while urban governance and people’s experiences have significant positive impacts on intrinsic, instrumental, and institutional values. The methodology combines bottom-up (based on grounded theory analysis of online user reviews) and top-down (literature review) approaches, ensuring the authenticity and theoretical depth of the questionnaire. The findings offer in-depth understanding and practical guidance for future HER work, contributing to bridging the knowledge gap in this field and providing a reference for urban managers and planners to balance preservation, development, and public interests in historic environment regeneration.
Predicting Landslide Deposit Zones: Insights from Advanced Sampling Strategies in the Ilopango Caldera, El Salvador
Authors: Calderon-Cucunuba Laura Paola , Argueta-Platero Abel Alexei , Fernández Tomás , Mercurio Claudio , Martinello Chiara , Rotigliano Edoardo , Conoscenti Christian
Published: January 2025

In landslide susceptibility modeling, research has predominantly focused on predicting landslides by identifying predisposing factors, often using inventories primarily based on the highest points of landslide crowns. However, a significant challenge arises when the transported mass impacts human activities directly, typically occurring in the deposition areas of these phenomena. Therefore, identifying the terrain characteristics that facilitate the transport and deposition of displaced material in affected areas is equally crucial. This study aimed to evaluate the predictive capability of identifying where displaced material might be deposited by using different inventories of specific parts of a landslide, including the source area, intermediate area, and deposition area. A sample segmentation was conducted that included inventories of these distinct parts of the landslide in the hydrographic basin of Lake Ilopango, which experienced debris flows and debris floods triggered by heavy rainfall from Hurricane Ida in November 2009. Given the extensive variables extracted for this evaluation (20 variables), the Induced Smoothed (IS) version of the Least Absolute Shrinkage and Selection Operator (LASSO) methodology was employed to determine the significance of each variable within the datasets. Additionally, the Multivariate Adaptive Regression Splines (MARS) algorithm was used for modeling. Our findings revealed that models developed using the deposition area dataset were more effective compared with those based on the source area dataset. Furthermore, the accuracy of models using deposition area data surpassed that of that using data from both the source and intermediate areas.
Sirtuin-1 Regulates Mitochondrial Calcium Uptake Through Mitochondrial Calcium Uptake 1 (MICU1)
Authors: Zhang Xinyi , Liu Shuhu , Su Yanshan , Zhang Ling , Guo Ting , Wang Xuemin
Published: January 2025

Mitochondria play a central role in cell biological processes, functioning not only as producers of ATP but also as regulators of Ca2+ signaling. Mitochondrial calcium uptake occurs primarily through the mitochondrial calcium uniporter channel (mtCU), with the mitochondrial calcium uptake subunits 1, 2, and 3 (MICU1, MICU2, and MICU3) serving as the main regulatory components. Dysregulated mitochondrial calcium uptake is a hallmark of cellular degeneration. Sirtuin 1 (SIRT1), a key regulator of cellular metabolism, plays a critical role in aging and various neurodegenerative conditions. By blocking SIRT1 using EX527 or shSIRT1, we observed mitochondrial structural fragmentation as well as intensified and prolonged mitochondrial calcium overload. Our study revealed a direct interaction between SIRT1 and MICU1. Notably, SIRT1 inhibition resulted in reduced MICU1 expression, hence led to mitochondrial calcium overload, illustrating the unconventional role of SIRT1 in governing mitochondrial function.
Assessing the Relationship of Different Levels of Pain to the Health Status of Long-Term Breast Cancer Survivors: A Cross-Sectional Study
Authors: Álvarez-Salvago Francisco , Figueroa-Mayordomo Maria , Molina-García Cristina , Pujol-Fuentes Clara , Atienzar-Aroca Sandra , de Diego-Moreno Manuel , Medina-Luque Jose
Published: January 2025

Purpose: This study investigated the relationship between different pain levels in the affected arm and health status in long-term breast cancer survivors (LTBCSs) and identified predictors of pain at this stage of long-term survivorship. Methods: A cross-sectional study of 80 participants categorized LTBCSs by pain levels in the affected arm into three groups: no pain (0–0.99), mild pain (1–3.99), and moderate to severe pain (4–10). Variables assessed at least 5 years since diagnosis include pain in the non-affected arm, pain interference, cancer-related fatigue (CRF), physical activity (PA) level, fitness condition, mood state, and health-related quality of life (HRQoL). Results: A total of 36.25% of LTBCSs have no pain, 30% have mild pain, and 33.75% have moderate to severe pain. Furthermore, pain presence was associated with increased pain in the non-affected arm, pain interference, CRF, mood disturbances, and physical inactivity, as well as a decreased HRQoL (all p < 0.05). Regression analysis found “upset by hair loss”, CRF “affective domain”, “dyspnea”, and “alcohol consumption” as significant predictors of higher levels of pain in the affected arm (r2 adjusted = 0.646). Conclusions: A total of 63.75% of LTBCSs continue to experience mild to moderate to severe pain in the affected arm, negatively impacting their physical, mental, and emotional health status, with increased pain severity ≥5 years beyond cancer diagnosis. “Upset by hair loss”, CRF “affective domain”, “dyspnea”, and alcohol consumption collectively explain 64.6% of the affected-arm pain level in LTBCSs.
Comparing the Movement System Impairment Method and Routine Physical Therapy for Knee Pain: A Randomized Clinical Trial
Authors: Farazdaghi Mohammadreza , Sadeghi Hassan , Alipour Haghighi Marjan , Alshammari Salem M.
Published: January 2025

This study explores the effectiveness of the Movement System Impairment (MSI) model compared to traditional physiotherapy for treating knee pain. Fifty patients with unilateral knee pain participated, with their femur, tibia, and knee alignment assessed in nine functional positions. Evaluations included the Tegner Activity Scale, Knee Injury and Osteoarthritis Outcome Score (KOOS), muscle power, extensibility, and pain levels. Patients were randomly assigned to either the MSI treatment group, which focused on identifying and correcting faulty movements, or a routine physiotherapy group that received general strengthening and stretching exercises. Results indicated that both treatment approaches improved muscle power in hip abductors and lateral rotators, as well as scores on the Tegner Activity Scale and the KOOS. Notably, the MSI group demonstrated greater improvements in the muscle power of the hip lateral rotators and knee extensors and a significant reduction in knee pain during walking compared to the routine group (p = 0.005). In conclusion, both treatments enhanced pain, function, and muscle strength, while the MSI model significantly reduced knee pain in walking and improved hip and knee muscle power compared to routine physiotherapy.
Interfacial Shear Fracture Behavior of C18150Cu/1060Al/C18150Cu Trilayered Composite at Different Temperatures
Authors: Cai Huisheng , Yang Siqi , Wang Qudong , Zhao Yuchao , Jia Qixiang , Ebrahimi Mahmoud , Liu Liang , Guo Feng , Shang Zhengping
Published: January 2025

Interfacial shear fracture behavior of C18150Cu/1060Al/C18150Cu trilayered composite at different temperatures, which was fabricated by high-temperature oxygen-free hot rolling technology. The interfacial microstructure, interfacial shear strength, interfacial shear fracture morphology, and microstructure near the shear fracture were systematically investigated. The results reveal that the composite exhibits a metallurgical and mechanical bonding interface, along with mechanical interlocking between the copper and aluminum. As the testing temperature increases, the interfacial shear strength decreases. At temperatures below 150 °C, the strength remains stable, but it sharply decreases at temperatures above 150 °C. Specifically, the interfacial shear strength is 56.8 MPa at room temperature and 20.9 MPa at 350 °C. When the testing temperature is below 100 °C, the interfacial shear fracture predominantly occurs at the interface between the copper alloy and intermetallics. Also, aluminum is attached to the copper surface of the shear fracture, and the size and quantity of attached aluminum increase with the increase in temperature. When the testing temperature exceeds 100 °C, curled aluminum appears on the copper layer, and a large number of intermetallics are attached to the aluminum surface. This indicates that the bonding strength between intermetallics and aluminum is higher than that between intermetallics and copper.
Mechanical Properties and Microstructure Evolution of Al-Li Alloy Under the PHF Process
Authors: Gong Zhiang , Huang Xiang , Wang Peiliao , Ma Huijuan
Published: January 2025

Currently, Al-Li alloys have been widely concerned in the aerospace and other fields due to their excellent comprehensive mechanical properties. However, the limitation of the long thermomechanical treatment still needs further improvement. Therefore, for an Al-Li alloy with multiple strengthening phases, this work proposes a pre-strain and pre-aged hardening warm forming (PHF) process. In the process, the multiphase precipitation and phase transformation are regulated by macro-control of the pre-strain, pre-aging, and warm forming stages. It is discovered that the 2A97 Al-Li alloy, with “7% pre-strain + 80 °C/16 h pre-aging + 250 °C/10 min warm forming”, exhibits the relatively optimal tensile/yield strength of 565.3 MPa/531.2 MPa. The addition of pre-strain facilitates the nucleation and precipitation of T1 phases through the consumption of δ′ phases and θ′ phases and promotes dynamic recrystallization during the warm forming process. The fine and uniform T1 phases are observed at the warm-maintaining time of 10 min. However, further extension of warm-maintaining time results in the coarsening of T1 phases and the reduction in strength. The proposed PHF process significantly shortens the thermomechanical treatment cycle of Al-Li alloys, which provides theoretical guidance for exploring the new short-process forming method.
Metal Ions Fortified Tannin-Furanic Rigid Foam: The Impact on the Uniformity and Mechanical Performance
Authors: Yang Yang , Wu Haizhu , Zhang Jun , Li Fajian , Charrier Bertrand , Essawy Hisham , Pizzi Antonio , Zhou Xiaojian , Chen Xinyi
Published: January 2025

Tannin-furanic foams with excellent properties have attracted increasing interest due to their advantages such as easy preparation, light weight, and thermal insulation. However, unsatisfactory mechanical strength has limited the expansion of their applications. Herein, three different metal ions (Cu2+, Fe3+, and Zn2+) were chosen to enhance the properties of tannin-furanic foam prepared by mechanical stirring provoked a foaming approach. The positive effects originating from the complexation are attributed to the associated connection between tannin molecules and metal ions. The results indicated that the apparent performance was improved, resulting in even foam cell structures. The apparent densities for the tannin-furanic foam modified with metal ions were located in the range of 36.57–47.84 kg/m3, showing the feature of lightweight material. The enhanced mechanical strength was verified by the compression strength (0.097–0.163 MPa) and pulverization ratio (7.57–11.01%) of the modified foams, which increased by 56–163% and decreased by 61–73%, respectively, in comparison with tannin-furanic foam without the metal ions. Additionally, the thermal conductivity of the modified tannin-furanic foams was in the range of 0.0443 to 0.0552 W/m·K. This indicates that they inherited the excellent thermal insulation typically associated with tannin-based foams. Interestingly, higher mechanical performance was obtained by comparison with other bio-sourced foams even with similar densities. In summary, by introducing only a small amount of metal ions, the foam performance was greatly improved, with a moderate cost increase, which reflects a good development prospect.
Six Sigma-Based Mathematical Optimization Framework for Flux-Switching Machines: A Roadmap for Quality, Performance, and Manufacturing Tolerances
Authors: Abunike Chiweta E. , Okoro Ogbonnaya I. , Aphale Sumeet S.
Published: January 2025

Flux-switching wound field machines (FSWFMs) offer high torque density and independence from rare-earth materials, making them promising candidates for sustainable electric vehicles and industrial applications. However, their adoption is limited by challenges such as high torque ripple, efficiency variations, and sensitivity to manufacturing tolerances. This study presents a Design for Six Sigma (DFSS) optimization framework that integrates sensitivity analysis, response surface modeling (RSM), and multi-objective genetic algorithms to address these challenges. The optimized solution reduces torque ripple by 7.69%, improves torque output, and enhances energy efficiency. By incorporating Six Sigma principles, the framework ensures robust performance under manufacturing variations, bridging the gap between theoretical optimization and practical implementation. This scalable and efficient methodology establishes FSWFMs as viable solutions for industrial applications, revolutionizing electric machine design.
Research on Tightening Technique of Turbopump Shaft System Based on Elongation Method
Authors: Wang Zelin , Zhou Liang , Jin Guangyuan , Han Ao , Gu Weide
Published: January 2025

As the key role of turbopumps in spacecraft engines becomes increasingly prominent, accurate control of their shaft system tightening force is significant to ensure the stable operation of the engines. Although the traditional torque method has been widely used in the tightening of threaded connections, the tightening force is easily affected by the quality of threads and lubrication conditions, and the accuracy and consistency are poor. This paper investigates the elongation method based on the turbopump shaft system tightening force control method. It is applied to the turbopump rotor assembly scenario for the first time. The performance of the torque and elongation methods under different thread qualities and lubrication conditions is compared through experiments. The experimental results show that the elongation method has significant advantages in improving the consistency and accuracy of the tightening force, especially under poor thread fit or different lubrication conditions.
Blockchain for Mass Customization: The Value of Information Sharing Through Data Accuracy by Contract Coordination
Authors: Ye Zhening , Wang Jie , Zhao Huida
Published: January 2025

This study provides the game-theoretical framework to investigate the relationship between the blockchain service and mass customization in the environment of information sharing and contract coordination. Specifically, we construct the game-theoretical models of the manufacturer and the retailer to discuss the optimal strategy of information sharing by the retailer in the case of mass customization. The result explores the conditions of information sharing for the retailer because she understands the end market information of nearby consumers. This discussion helps us to understand that the motivation of the manufacturer pays for the retailer’s construction of a blockchain system in the case of two types of products, such as a standard product and a customization product. Finally, we use the method of contract coordination to obtain the optimal strategy. Results reveal that information costs significantly impact sharing decisions, and cost-sharing contracts can incentivize retailers to share market data. This study has two main contributions. On the one hand, this study adopts the blockchain service for mass customization by supporting contract coordination, showing the technical value of avoiding false information and tampering-proof. On the other hand, although big data has the same information sharing function, this technology can’t play the role of secure data transmission. In order to increase the accuracy of information sharing, we analyze the fusion results of two technologies in the aspect of increasing the accuracy of data sharing, which better reveals the technical value.