bluuebunny/crossref_metadata_2025 huggingface dataset:
Energy performance of compressed biogas production from co-digestion of Salix and dairy manure: factoring differences between Salix varieties
Authors: Kalita Saurav , Potter Hanna Karlsson , Nordberg Åke , Sandgren Mats , Hansson Per-Anders
Published: July 2023

Biogas from anaerobic digestion is a versatile energy carrier that can be upgraded to compressed biogas (CBG) as a renewable and sustainable alternative to natural gas. Organic residues and energy crops are predicted to be major sources of bioenergy production in the future. Pre-treatment can reduce the recalcitrance of lignocellulosic energy crops such as Salix to anaerobic digestion, making it a potential biogas feedstock. This lignocellulosic material can be co-digested with animal manure, which has the complementary effect of increasing volumetric biogas yield. Salix varieties exhibit variations in yield, composition and biomethane potential values, which can have a significant effect on the overall biogas production system. This study assessed the impact of Salix varietal differences on the overall mass and energy balance of a co-digestion system using steam pre-treated Salix biomass and dairy manure (DaM) to produce CBG as the final product. Six commercial Salix varieties cultivated under unfertilised and fertilised conditions were compared. Energy and mass flows along this total process chain, comprising Salix cultivation, steam pre-treatment, biogas production and biogas upgrading to CBG, were evaluated. Two scenarios were considered: a base scenario without heat recovery and a scenario with heat recovery. The results showed that Salix variety had a significant effect on energy output-input ratio (R), with R values in the base scenario of 1.57–1.88 and in the heat recovery scenario of 2.36–2.94. In both scenarios, unfertilised var. Tordis was the best energy performer, while the fertilised var. Jorr was the worst. Based on this energy performance, Salix could be a feasible feedstock for co-digestion with DaM, although its R value was at the lower end of the range reported previously for energy crops.
Analysis of Controlled Diode Bridge Clamped based 3L-VSI using Space Vector approach
Authors: Sonar Santosh , Mondal Sanjoy
Published: July 2023

In this paper, some important aspects related to operating modes, dead time in inverter switches, merits, demerits and PWM technique implementation of controlled diode bridge clamped based 3L-VSI is discussed in detail. A high-frequency PWM technique based on the principle of space vector concept is used for the analysis of switching states. Two main type of switching techniques based on space vector approach namely, continuous and discontinuous PWM techniques have been used. For the discontinuous PWM sequence, the main focus here is to accurately select the switching sequence for the first switching cycle so that nearest three-level switching can be achieved without any extra switching instant over a fundamental cycle of the output voltage. Dependence of modulation index on switching states selection has been pointed out. To verify the correctness of the proposed approach, simulation and experimental results are presented.
Reproductive strategies, free-swimming tadpoles, and natural history of the Santa Marta rocket frog “Colostethus” ruthveni Kaplan, 1997 (Anura: Dendrobatidae), with a review of the distribution of larval and reproductive characters in Dendrobatoidea
Authors: Polo-Córdoba Fredy , Linares-Vargas Katherin , Montes-Correa Andrés Camilo , Jiménez-Bolaño Juan David , Saboyá-Acosta Liliana , Granda-Rodríguez Hernán
Published: July 2023

Herein, we research several aspects of biology of the Santa Marta rocket frog “Colostethus”ruthvenifrom the Sierra Nevada de Santa Marta, Colombian Caribbean. Quantification of relative abundance and habitat use was provided. Likewise, free-swimming tadpoles and reproductive strategies were described. In addition, the distribution of larval and reproductive characters across Dendrobatoidea were examined as an approach for their evolution and to identify whether these can complement the diagnosis of the “C.”ruthvenigroup. We recorded 853 specimens of “C.”ruthveniin six localities, resulting in a fairly high relative abundance at each site. Leaf-litter and rocks were the most used substrata, although their proportion of uses varying across the sites. The external morphology of free-swimming tadpoles of “C.”ruthveniresembles the former members of theColostethussensu lato. The courtship is a complex interaction of acoustic, visual, and tactile displays, which leads to the cephalic amplexus. "Colostethus"ruthvenishowed wide variation in oviposition sites, including natural and artificial substrates at ground level, as well as creeping vegetation above the ground or water. Therefore, we consider that the species exhibits multiple reproductive modes, one of them previously unknown for anurans. Several larval and reproductive characters of “C.”ruthveniconsist of a compendium of ancestral states. However, some characters are of special interest because these could be considered reversions to ancestral states or apomorphies, which could constitute synapomorphies of the “C.”ruthvenigroup if demonstrated to occur in the other undescribed members of the complex. In addition, we evidenced that "C."ruthveniis the only Dendrobatine with considerably narrow A2-gap. All this information on morphology and natural history provides insight into the evolutionary processes of poison frogs and provides basic information necessary for the management of this potentially endangered species.
Non-ECG-triggered dual-source CTA in children with CHD
Authors: Zhang Shipeng , Zhu Dalin , Mao Baohong , Xie Yijing
Published: July 2023

Objective: To explore the value of non-electrocardiogram-triggered(non-ECG-triggered) on third-generation dual-source CT application in children with congenital heart disease (CHD) in a high heart rate.
Methods:Data on children with CHD received cardiac CT angiography (CTA) were collected between November 2019 and March 2021. CT images were obtained using two different protocols: non-ECG-triggeredand retrospectively-ECG-triggered (retro-ECG-triggered). All children received transthoracic echocardiography (TTE) before surgery . Sex, age, weight, heart rate, volume CT dose index (CTDI vol), and dose length product (DLP) were recorded, and the effective dose (ED) was calculated. Image quality was rated using five-point Likert scales and the diagnostic values of CTA and TTE were compared.
Results:Children’s age ranged from 1 day to 34 months, with minimum and maximum heart rates of 90 bpm and 160 bpm. There were significant differences between the retro- and non-ECG-triggered groups in the average tube current (54.95±23.52 vs. 45.47±24.65 mAs, p=0.003), CTDI vol (2.41±1.6 vs. 0.58±0.27 mGy, p<0.001), DLP (44.43±34.65 vs. 9.92±5.48 mGy.cm, p<0.001), and ED (1.48±0.90 vs. 0.35±0.17 mSv, p<0.001). There was no difference between the two protocols in the demonstration of extracardiac and intracardiac malformations (all p≥0.05). The diagnostic accuracy of both retro- and non- ECG triggering in intracardiac and extracardiac malformations were high with no significant differences (p=1.00, 0.80). The diagnostic advantage of TTE is mainly in intracardiac malformations (p=0.03, 0.01).
Conclusions: High-pitch non-ECG-triggered CTA cansignificantly reduce radiation dose,whereas there was no significant difference in image quality and diagnostic accuracy between non- and retro-ECG-triggered CTA.
Non-Target Screening of Surface Water Samples to Identify Exposome-Related Pollutants: A Case Study from Luxembourg
Authors: Aurich Dagny , Diderich Philippe , Helmus Rick , Schymanski Emma L.
Published: July 2023

Background
Non-target screening of surface water samples collected over an extended period can reveal interesting temporal patterns in exposome-related pollutants. Additionally, geographical data on pollution sources close to the sampling sites, chemical classification data and the consideration of flow paths can provide valuable information on the origins and potential threat of tentatively identified chemical compounds. In this study, 271 surface water samples from 20 sampling sites across Luxembourg were analysed using high resolution mass spectrometry, complementing routine target monitoring efforts in 2019–2022. Data analysis was performed using the open source R-package patRoon, which offers a customizable non-target workflow. By employing open source workflows featuring scoring terms, like spectral match and applying identification levels, tentative identifications can be prioritized, e.g. based on spectral similarity. Furthermore, by utilizing supplementary database information such as PubChemLite annotation categories and classification software such as classyFire, an overall assessment of the potential threats posed by the tentatively identified chemicals was conducted, enabling the prioritization of chemicals for future confirmation through targeted approaches.
Results
The study tentatively identified 375 compounds associated with the exposome including benzenoids, organoheterocyclic compounds, and organic phosphoric acids and derivatives (12 classyFire superclasses, 50 sub-classes). The classification analysis not only revealed temporal variations in agrochemicals, with the majority of identifications occurring in May to July, but also highlighted the prevalence of pharmaceuticals such as venlafaxine in surface waters. Furthermore, potential sources of pollutants, like metallurgic industry or household products were explored by considering common uses and geographical information, as commercial uses of almost 100% of the identified chemicals are known. 41 chemicals were suggested for potential inclusion to governmental monitoring lists for further investigation.
Conclusions
The findings of this study complement existing knowledge on the pollution status of surface water in Luxembourg and highlight the usefulness of non-target screening for identifying temporal and spatial trends in pollutant levels. This approach, performed in a complementary manner to routine monitoring, can help to tentatively identify chemicals of concern for potential inclusion in target monitoring methods following additional confirmation and quantification efforts.
A simple coin for a 2d entangled walk
Authors: Zahed Ahmadullah , Sen Kallol
Published: July 2023

We analyze the effect of a simple coin operator, built out of Bell pairs, in a 2d Discrete Quantum Random Walk (DQRW) problem. The specific form of the coin enables us to find analytical and closed form solutions to the recursion relations of the DQRW. The coin induces entanglement between the spin and position degrees of freedom, which oscillates with time and reaches a constant value asymptotically. We probe the entangling properties of the coin operator further, by two different measures. First, by integrating over the space of initial tensor product states, we determine the Entangling Power of the coin operator. Secondly, we compute the Generalized Relative Rényi Entropy between the corresponding density matrices for the entangled state and the initial pure unentangled state. Both the Entangling Power and Generalized Relative Rényi Entropy behaves similar to the entanglement with time. Finally, in the continuum limit, the specific coin operator reduces the 2d DQRW into two 1d massive fermions coupled to synthetic gauge fields, where both the mass term and the gauge fields are built out of the coin parameters.
Earnings and market ratio: Additional evidence from Jordanian banks
Authors: Fawzi Shubita Mohammad
Published: July 2023

The primary objective of this study is to investigate the correlation between profitability and the banks market value, while controlling for bank size as indicated by total assets. Two main models are analyzed, namely the benchmark model and the main model, to estimate the impact of high and low profitability on market value. The sample for this study consists of Jordanian banks covering the period from 2010 to 2020. The study results reveal that banks with high profitability exhibit a higher market value compared to those with low profitability, underscoring the crucial role of profitability as a determinant of bank value. Furthermore, the study establishes a link between low and high ROE and market value, indicating that variations in ROE significantly affect market value. Moreover, the study demonstrates a positive link between earnings and market value, emphasizing the significance of bank earnings in influencing market value. Lastly, the study emphasizes the role of bank size in shaping the link between ROE and market value, highlighting the importance of considering bank size when examining the link between profitability and market value.
AcknowledgmentI thank Amman Arab University for funding this research.
One-step Bio-guided Isolation of Secondary Metabolites from the
Endophytic Fungus Penicillium crustosum Using High-resolution
Semi-preparative HPLC
Authors: Alfattani Abdulelah , Queiroz Emerson Ferreira , Marcourt Laurence , Leoni Sara , Stien Didier , Hofstetter Valerie , Gindro Katia , Perron Karl , Wolfender Jean-Luc
Published: July 2023

Background:

An endophytic fungal strain Penicillium crustosum was isolated from the
seagrass Posidonia oceanica and investigated to identify its antimicrobial constituents and characterize
its metabolome composition. The ethyl acetate extract of this fungus exhibited antimicrobial
activity against methicillin-resistant Staphylococcus aureus (MRSA) as well as an anti-quorum
sensing effect against Pseudomonas aeruginosa.

Methods:

The crude extract was profiled by UHPLC-HRMS/MS, and the dereplication was assisted
by feature-based molecular networking. As a result, more than twenty compounds were annotated in
this fungus. To rapidly identify the active compounds, the enriched extract was fractionated by semipreparative
HPLC-UV applying a chromatographic gradient transfer and dry load sample introduction
to maximise resolution. The collected fractions were profiled by 1H-NMR and UHPLC-HRMS.

Results:

The use of molecular networking-assisted UHPLC-HRMS/MS dereplication allowed preliminary
identification of over 20 compounds present in the ethyl acetate extract of P. crustosum. The chromatographic
approach significantly accelerated the isolation of the majority of compounds present in the active
extract. The one-step fractionation allowed the isolation and identification of eight compounds (1-8).

Conclusion:

This study led to the unambiguous identification of eight known secondary metabolites
as well as the determination of their antibacterial properties.
Diphenyl Ethers: Isolation, Bioactivities and Biosynthesis
Authors: Liu Bing , Wang Yuxin , Chen Ning , Li Chenxue , Zhao Jintong , Li Ting
Published: July 2023

Diphenyl ethers (DPEs) are mainly produced by microorganisms and plants. The chemical
structure of DPEs is relatively simple, and all of these compounds have the structure of biphenyl
ethers in their chemical structure, the difference being the difference in the substituents on the benzene
ring. Several recent studies have shown antibacterial, antioxidant, antitumor, antitumor, antihemolytic,
neuroprotective, and anti-Alzheimer effects. DPEs could be candidate compounds for the
treatment of Alzheimer's disease, by inhibiting the aggregation of Aβ42. Many DPEs from natural
products exhibit good biological activity and they play an important role in the control of microbial
infections. Diphenyl ethers have a wide range of applications and research value in the fields of pesticides,
pharmaceuticals, textiles, household products, and public health. In this paper, we review the
research progress of diphenyl ethers isolated from marine and plant endophytic sources in recent
years, including their biosynthesis, and lay the foundation for further utilization and development.
Взаимосвязь аномальной интенсификации отрывного течения и экстраординарных перепадов давления в канавке на пластине при изменении угла наклона от 0 до 90-=SUP=-o-=/SUP=-
Authors: Исаев С.А. , Гувернюк С.В. , Никущенко Д.В. , Судаков А.Г. , Синявин А.А. , Дубко Е.Б.
Published: July 2023

A numerical and physical study of the air turbulent flow around a plate (with a long inclined groove of moderate depth which has hemispherical ends) is performed at a Reynolds number of 6.7×104, which is determined by the width of the groove. The inclined angle of the groove with respect to the oncoming flow varies from 0 to 90°. The stationary near-wall flow of an incompressible viscous medium is simulated by solving the Reynolds-averaged Navier-Stokes equations, closed using the shear stress transport model. The static pressure distributions in the single grooves are measured in a wind tunnel at the Institute of Mechanics of Moscow State University. Inclined angles of the grooves are determined, at which an anomalous intensification of the separated flow is observed. The resulting extraordinary pressure drops in the grooves are in a good agreement with ultra-high absolute values of negative relative friction. Velocities of the return and secondary swirling flow turn out to be comparable with the oncoming flow velocity.
Tratamiento exitoso del carcinoma de meibomio en una vaca
Authors: Kibar Kurt Büşra , Bilgen Şen Zeynep , Akkoç Ayşe Nur
Published: July 2023

Objective. The aim of this study was to present the diagnosis and treatment method of an extraordinary meibomian carcinoma in a cow. Materials and methods. A 5-year-old, Holstein cow presented with a right lower eyelid mass with ocular signs of mucopurulent discharge, conjunctival hyperemia and ocular discomfort. On physical examination, it was noted that the general condition was good, but there was a mass lesion in the third eyelid. The mass arising from the inner surface of the right lower eyelid was surgically excised and examined histopathologically. Results. The tumor mass was defined as meibomian carcinoma after microscopic examination. Conclusions. Meibomian carcinoma is a rare disease that shows certain features of malignancy such as invasion and pleomorphism as well as mitosis. This case presentation can be considered to contribute to the literature as this is a rare tumor in cattle, to the best of our knowledge it is the first report of a case originating from the third eyelid, and wide surgical excision was sufficient for treatment.
Prevalencia de parásitos digestivos de perros del centro de México
Authors: Hernandez-Valdivia Emmanuel , Martínez-Robles Juandedios , Valdivia-Flores Arturo Gerardo , Cruz-Vazquez Carlos , Ortiz-Martinez Raúl , Quezada-Tristan Teódulo
Published: July 2023

Objective. To identify the abundance and prevalence in infection by digestive parasites (DPs) and their seasonal distribution in dogs from Aguascalientes, Mexico. Materials and Methods. A statistically representative sample (n=927) systematically selected (first in each 10), of stray or owners-surrendered dogs at a local animal control and welfare center was examined. Immediately after legal euthanasia (pre-anesthetic plus anesthetic overdose), the entire intestine was removed, and intestinal contents were sieved; macroscopically visible helminths were collected; a stool sample was then examined in duplicate by flotation, McMaster, and Lugol’s-stained smear. Results. The prevalence of DPs was 42.8%. Elevated prevalence values were detected among puppies (60.6%), in dogs with lower body weight (72.7%), also in stray dogs (57.5%) compared with those voluntarily surrendered by their owners (37.5%; p<0.01); additionally, more cases were found during temperate seasons (51.0 vs 33.1%; p<0.01). The DPs prevalence values were determined: Dipylidium caninum (26.2%), Taenia spp. (4.0%), Giardia spp. (13.6%), Cystoisospora spp. (7.8%), Sarcocystis spp. (5.3%); Toxocara canis (14.0%), Ancylostoma caninum (12.9%), Uncinaria stenocephala (4.2%), Toxascaris leonina (0.5%), and Oncicola canis (0.1%). The DPs reached a high prevalence with hundreds of adult forms in the intestine and thousands of eggs or oocysts per gram of feces. Conclusions. These results indicated a high prevalence of DPs in dogs of central Mexico, especially in the population segment constituted by stray, young and underweight animals, which is relevant in public health due to its recognized zoonotic capacity.
Edad a la pubertad en corderos Criollos “Obispo” en La Montaña de Guerrero, México
Authors: Ulloa-Arvizu Raúl , Martínez-Rojero Rubén D.
Published: July 2023

Objective. Determine the age and body weight at the onset of puberty in Criollo Obispo lambs from a sheep herd. Materials and methods. The present study was carried out ex situ (18⁰ 15’ 52’’ LN). 10 lambs born during the spring were used, which were detected at 3 m of age. The detachment of the urethral process was verified at the age of 5.0 to 5.5 months of age. A semen sample was taken every two weeks with the help of an electro-ejaculator. Sperm concentration was evaluated with a digital photometer, while light microscopy was used for progressive motility and sperm morphology. The Kaplan-Meier procedure was used to estimate the risk or survival time function.to determine the days of onset of puberty. A male is considered to have entered puberty when the ejaculate registers at least 150 million sperm per mL, with a minimum of 50% abnormal cells and a motility greater than 30%. Results. It was observed that the average age of onset of puberty was 211.4±25.09 d, with a body weight of 19.3±1.27 kg. Conclusions. Criollo Obispo lambs begin puberty at 7 m of age and with a body weight of 19.3±1.27 kg.
An Analysis of the Prevalence and Trends in Drug-Related Lyrics on Twitter (X): Quantitative Approach (Preprint)
Authors: Luo Waylon , Jin Ruoming , Kenne Deric , Phan NhatHai , Tang Tang
Published: July 2023

BACKGROUND

The pervasiveness of drug culture has become evident in popular music and social media. Previous research has examined drug abuse content in both social media and popular music; however, to our knowledge, the intersection of drug abuse content in these 2 domains has not been explored. To address the ongoing drug epidemic, we analyzed drug-related content on Twitter (subsequently rebranded X), with a specific focus on lyrics. Our study provides a novel finding on the prevalence of drug abuse by defining a new subcategory of X content: “tweets that reference established drug lyrics.”

OBJECTIVE

We aim to investigate drug trends in popular music on X, identify and classify popular drugs, and analyze related artists’ gender, genre, and popularity. Based on the collected data, our goal is to create a prediction model for future drug trends and gain a deeper understanding of the characteristics of users who cite drug lyrics on X.

METHODS

X data were collected from 2015 to 2017 through the X streaming application programming interface (API). Drug lyrics were obtained from the Genius lyrics database using the Genius API based on drug keywords. The Smith-Waterman text-matching algorithm is used to detect the drug lyrics in posts. We identified famous drugs in lyrics that were posted. Consequently, the analysis was extended to related artists, songs, genres, and popularity on X. The frequency of drug-related lyrics on X was aggregated into a time-series, which was then used to create prediction models using linear regression, Facebook Prophet, and NIXTLA TimeGPT-1. In addition, we analyzed the number of followers of users posting drug-related lyrics to explore user characteristics.

RESULTS

We analyzed over 1.97 billion publicly available posts from 2015 to 2017, identifying more than 157 million that matched drug-related keywords. Of these, 150,746 posts referenced drug-related lyrics. Cannabinoids, opioids, stimulants, and hallucinogens were the most cited drugs in lyrics on X. Rap and hip-hop dominated, with 91.98% of drug-related lyrics from these genres and 84.21% performed by male artists. Predictions from all 3 models, linear regression, Facebook Prophet, and NIXTLA TimeGPT-1, indicate a slight decline in the prevalence of drug-related lyrics on X over time.

CONCLUSIONS

Our study revealed 2 significant findings. First, we identified a previously unexamined subset of drug-related content on X: drug lyrics, which could play a critical role in models predicting the surge in drug-related incidents. Second, we demonstrated the use of cutting-edge time-series forecasting tools, including Facebook Prophet and NIXTLA TimeGPT-1, in accurately predicting these trends. These insights contribute to our understanding of how social media shapes public behavior and sentiment toward drug use.
Proteína Bm86 y su potencial uso como vacuna contra garrapatas en el ganado bovino. Revisión
Authors: Galván Arellano Dulce María , Vieyra Reyes Patricia , Montes de Oca Jiménez Roberto , Ortega Lopez Jaime , Martínez Arzate Saúl Gabriel , Rivas Santiago Bruno , Vázquez Chagoyán Juan Carlos
Published: July 2023

Las infestaciones de garrapatas representan una gran dificultad para la producción de ganado bovino en países tropicales y subtropicales alrededor del mundo. Las formas tradicionales de combate a esta plaga son químicos (acaricidas) y manejo integral de pastizales. Sin embargo, estos métodos no han logrado controlar de manera contundente la presencia de este ectoparásito. Lo anterior ha llevado a la búsqueda de vacunas que permitan el control de estos parásitos. Actualmente, se cuenta con inmunógenos que contienen el antígeno intestinal Bm86 de Rhipicephalus microplus, los cuales han demostrado ser una alternativa efectiva, al reducir las poblaciones de garrapatas y el uso de acaricidas sintéticos. No obstante, el polimorfismo de este locus en garrapatas de distintas zonas geográficas representa una limitante en su efectividad. Se han realizado un número importante de investigaciones acerca del gen Bm86 como antígeno vacunal, por lo que, en este documento, se presenta una actualización de las investigaciones realizadas con este antígeno y su potencial uso como control inmunológico para reducir las infestaciones de garrapatas en el ganado bovino.
PERKEMBANGAN PEMBELAJARAN BERDIFERENSIASI DALAM KURIKULUM MERDEKA PADA PENDIDIKAN ANAK USIA DINI
Authors: Ngaisah Nur Cahyati , * Munawarah , Aulia Reza
Published: July 2023

Sistem drilling yang diterapkan disekolah melalui metode hafalan terlalu menuntut anak agar dapat membaca, menulis dan berhitung dengan cepat sehingga anak merasa terkekang tanpa merasakan kebebasan dalam belajar. Pembelajaran berdiferensiasi sangat menghargai keragaman kemampuan anak dan memberi kebebasan anak dalam proses belajar. Hal tersebut dapat diimplementasikan dengan kurikulum merdeka di jenjang PAUD yang memiliki sistem merdeka bermain. Penelitian ini menggunakan metode studi pustaka dengan mengumpulkan literatur yang terkait dengan topik penelitian. Sumber data dalam penelitian ini berasal dari jurnal, conference, review, laporan, buku, dan lain sebagainya yang bersifat informatif. Hasil penelitian menunjukan bahwa: 1) pembelajaran berdiferensiasi pada pendidikan anak usia dini memiliki tiga elemen penting yaitu konten, proses dan produk yang dikembangkan oleh Pendidik. Tiga elemen ini membantu proses pembelajaran dengan cara pendidik menyiapkan perangkat pembelajaran, dengan menyesuaikan minat anak dan sesuai profil belajar peserta didik; 2) Konsep pembelajaran berdiferensiasi sesuai dengan karakteristik pembelajaran dalam kurikulum merdeka dan bervalue modern. Dimana karakteristiknya bertumpu pada pengembangan karakter individu dan berpusat padaanak. 3) Prinsip pembelajaran berdiferensiasi mengupayakan fungsi pendidik berjalan secara optimal dalam memfasilitasi peserta didik baik sebelum, sedang dan sesudah pembelajaran. 4) diketahui pembelajaran berdiferensiasi dapat diimplementasikan pada pendidikan anak usia dini, dimana konsep, karakteristik, dan prinsip pembelajarannya bersesuaian dengan gagasan kurikulum merdeka. Selain itu, tantangan pembelajaran berdiferensiasi ialah menitikberatkan pada peran pendidik, sehingga mengharuskan tenaga pendidik memiliki kompetensi yang memadai.
PERKEMBANGAN OTAK PADA ANAK USIA DINI:KAJIAN DASAR NEUROLOGI DAN ISLAM
Authors: Jannah Miftahul
Published: July 2023

Otak adalah organ utama manusia untuk menjaga kesimbangan fisik dan psikis manusia mulai dari tahapan perkembangan dalam kandungan, bayi, kanak-kanak, remaja sampai usia dewasa dan lansia. Otak menuntun manusia untuk berperilaku positif dan negatif. Otak akan berfungsi positif dalam suasana lingkungan yang positif dan sebaliknya akan berkembang negatif dalam lingkungan yang negatif. Berat otak bayi yang baru lahir 370 g, kemudian pada usia tiga tahun berat otak anak menjadi sekitar seperempat sampai sepertiga dari berat otak orang dewasa, sekitar 1.400 sampai 1.500 g. Perkembangan otak ini dikenal dengan usia “Golden Age”. Setiap orangtua atau significant others yang membesarkan anak harus memahami bahwa pada anak usia dini otak akan berkembang pesat dan sel-sel sel saraf akan berfungsi kuat dan pesat jika diberikan stimulus respon  yang tepat. Maknanya anak akan sangat cepat memahami dan cepat meniru dan menghafal apa yang didengar, dilihat, dan diamatinya. Bagi setiap orang yang membesarkan anak, seorang pendidik, baby sitter pun harus mengerti dan memahami bahwa otak adalah organ tubuh manusia yang harus dilindungi dan dijaga agar tidak terkena benda benda keras dan tajam dan tidak terjadi benturan berat dan luka yang dalam yang menjadikan kerusakan pada tumbuh kembang otak. Kajian ini untuk menjadi referensi awal untuk mengetahui bagian bagian otak untuk mengetahui bahwa otak memiliki bagian-bagian yang memiliki fungsinya masing-masing sesuai dengan hasil kajian ilmiah para ahli saraf.
DIGITAL HR PLATFORMS AND ECOSYSTEMS IN PUBLIC ADMINISTRATION
Authors:   Russian Presidential Academy of National Economy and Public Administration, MARTYNOVA S.E. , BOGATYREVA T.G. ,   Russian Presidential Academy of National Economy and Public Administration
Published: July 2023

The global trend of digital transformation of public administration, the processes of its development in Russia have exposed the lack of modern personnel management technologies. The purpose of the article is to develop a conceptual framework for thinking about the platform and ecosystem approaches as tools to overcome the fragmentation of public sector workforce efforts. The research was based on the trends in the HR transformation of public administration, the basic definitions of digital HR platforms and ecosystems, and the emerging concepts of personnel management in the context of digitalization. The methods of content analysis, structural analysis, and a comparative method were used. As a result, the principles of building digital HR systems were identified, leading to an orderly and optimal interaction between participants, the parameters for building an advanced HR platform to provide a configuration that meets the modern needs of the state and civil servants, and success factors for creating digital HR ecosystems. The article was prepared as part of the research work of the state task of the RANEPA.
PATRIOTIC EDUCATION OF STUDENTS: SOCIOLOGICAL ANALYSIS
Authors:   Central Russian Institute of Management, Branch of RANEPA, ALEKSEYENOK A.A. , NALIVAIKO K.V. ,   Central Russian Institute of Management, Branch of RANEPA
Published: July 2023

The article touches upon an important problem for modern Russian society - the patriotic education of student youth. Solving this issue, it is necessary to consider this area, taking into account various aspects at this stage of the formation of the state, namely: the level of patriotism and patriotic feelings among the students, the main sources of knowledge about their homeland, the visualization of its image by young people, identifying the most memorable events that make more young people are proud of their country. The purpose of the work is to empirically substantiate the need for patriotic education of modern student youth as an important postulate of the spiritual revival of the nation. The term "patriotism" is mentioned in many fundamental sciences, in connection with which each scientist interprets it in his own way. However, any statement is based on the following basis - pride in one's Motherland, its success in the political arena, as well as victories in the sports and scientific fields, active citizenship, selflessness and devotion to one's state in the event of a danger that has arisen for it, conscious and all-consuming love to its people, its cultural characteristics and traditions. The proof of the above is the results of a sociological study conducted at the Department of Sociology and Social Technologies of the Central Russian Institute of Management - a branch of the RANEPA on the topic "Patriotic education of youth". This study covered such categories as "patriotism", "patriotic education", "image of the Motherland", "national spirit", "historical memory", "national identity". It is summarized that the patriotic education of student youth consists of various components, but its conscious position and the knowledge about the Motherland that were laid and continue to be in its mind at various stages of personality development are paramount.
METHODOLOGICAL BASES ORGANIZING THE EVALUATION OF INNOVATIVE PROJECTS BASED ON THE CONSTRUCTION OF A LOGICAL-STRUCTURAL MATRIX
Authors:   Central Russian Institute of Management, Branch of RANEPA, EREMINA I.A. , POLISHUCHENKO V.A. ,   Central Russian Institute of Management, Branch of RANEPA
Published: July 2023

The purpose is to develop methodological foundations for evaluating innovative projects based on the application of the “Due Diligence” standard and the real options method, followed by the construction of a logical-structural matrix. Research methodology: It is based on the "Due Diligence" standard used in the evaluation of innovative projects since the early 30s of the XX century. In its classical form, this approach is a complex analytical procedure aimed at determining the legality and investment attractiveness of a planned commercial transaction, merger, acquisition, investment, issue or other financial procedure in order to minimize possible risks and related financial losses and make a decision on investing capital. The object of the study is modern methods for evaluating innovative projects. The subject of the study is the peculiarities of organizing the evaluation of innovative projects in modern conditions for the implementation of an integrated approach to making managerial decisions regarding the introduction of innovations, comparative and systematic approaches, as well as general theoretical methods of analysis, synthesis, generalization, comparison. As a result, the authors carried out a comparative analysis of the main approaches to the evaluation of innovative projects, which made it possible to substantiate that the evaluation of an innovative project should be based on the real options method and the “Due Diligence” expert approach, followed by the construction of a logical-structural matrix. The advantage of this method is the possibility of a phased assessment of the project, taking into account various options for the combination of circumstances. This integrated approach to the evaluation of innovative projects allows us to consider not only the likelihood of various events, but also makes it possible to evaluate the effectiveness of the project, taking into account various options for getting out of the current situations. The integrated application of the real options method and the “Due Diligence” expert approach allows taking into account risks and reducing the level of influence of uncertainty on the assessment results, which determines the practical significance of the study.
Afectación de los procesos comunicativos de orden corporal en el contexto de aprendizaje por la mediación tecnológica
Authors: Arias Obando Daniela
Published: July 2023

Dentro del contexto educativo de la sociedad actual, una de las mayores falencias que se pueden vislumbrar corresponde a los procesos comunicativos dentro de los ambientes de aprendizaje. Esta problemática, potenciada por un mundo cada vez más volcado hacia lo digital, lo individual y lo virtual, ha generado un cambio que, aunque paulatino, puede ser trascendental en la historia de la humanidad, ya que se pasa de ser seres socialmente activos y presenciales, desenvueltos en un contexto que se basaba en la oralidad y el compartir de los individuos, a una sociedad caracterizada por un compartir desde la distancia, lo digital, lo virtual. En el presente artículo se analiza cómo los procesos comunicativos de orden corporal se afectan durante el aprendizaje en el contexto de formación de jóvenes del SENA, por el uso de mediaciones tecnológicas. La investigación que tuvo un enfoque mixto, permitió analizar desde lo cualitativo las afectaciones que se generaron en el desarrollo del lenguaje corporal cuando se usó la tecnología en los procesos de formación, además de identificar cada comportamiento no verbal en los ejercicios que requirieron el uso del cuerpo; y desde el análisis cuantitativo se identificó la frecuencia del uso de dichas expresiones no verbales. El trabajo fue no experimental, de corte transversal, a partir de la recolección de datos de la observación participante de 9 clases presenciales, registro de datos estadísticos de 44 videos y revisión audiovisual de 36 clases virtuales. En este la principal conclusión muestra que el uso de la tecnología sí limita y afecta el desarrollo del lenguaje corporal cuando esta es utilizada en su totalidad en los escenarios formativos y no como una herramienta de apoyo en escenarios presenciales.
Associated factors contributing abundance of fleas on rodents in plague endemic area of Karatu district, northern Tanzania.
Authors: Jakoniko Joshua , Massawe Apia , Mwega Elisa , Kessy Stella
Published: July 2023

Fleas are small wingless hematophagous insect that are frequently
infesting on rodents and other small mammals while acting as reservoirs
and vectors of many rodent borne zoonotic diseases including plague
infectious disease which is threat to the public health in many part of
the world including Tanzania. 291 rodents from nine species were
captured with Sherman traps in farm land, peridomestic areas, bush land
and forest buffer zone across wet and dry season in plague and
non-plague foci villages. Captured rodents were anaesthetized and 190
fleas comprising four species were collected and morphologically
identified with available dichotomous key. Dinopsyllus lypusus were
(46.32%), Ctenophthalmus spp (26.84%), Xenopsylla brasiliensis
(16.32%) and Xenopsylla cheopis (10.53%). 38.42% of fleas were
collected from Mastomy natalensis, 22.63% from Lemniscomys striatus and
18.42% from Rattus rattus. Highest flea infestation prevalence was
found on R.rattus and was strongly associated with X.cheopis and
X.brasiliensis. Specific flea index of X.cheopis on R.rattus was (01) in
plague foci and (<0.5) in non-plague foci villages. Result of
GLM final model indicated that flea abundance was significant influenced
by rodent species (p < .001), season (p= .031), habitat type
(p= .02), rodent weight (p < .001), rodent sex (p <
.001) and plague locations (p= .02). There was significance difference
in variation of flea abundance between rodent sexes (W = 9158.5, p =
.009) and a weak positive correlation between rodent’s weight and
abundance of fleas (R= 0.17, p< 0.05). Despite that, specific
flea index of X.cheopis on rats in both plague foci and non-plague foci
villages were not indicating alarming condition that would require
urgent control of fleas, still society should consistently adhere to
rodent and fleas control methods in order to limit their interaction to
the society especially in farm land and peridomestic areas where human
activities are high.
Development of a Fake News Detection Model Using Decision Tree Algorithm
Authors:   Department of Computer Science Oyo State College of Agriculture and Technology Igboora, Oyo State, Nigeria, Adeola Olajide O. , Bello, Ganiyat R , Oluwasola Babatunde S. , Lateef Kafayat R.
Published: July 2023

Over 500,000 Americans are influenced each year by fake news, which has an impact on society. Researchers are examining data on fake news identification and looking into machine learning models for a quicker and more accurate categorization as part of their investigation of false news detection techniques. This study's main objective is to examine, contrast, and evaluate how well three distinct machine learning algorithms do at spotting fake news. Decision tree, Random forest, and logistic regression are the machine learning algorithms. There are 21418 datasets available for real news, compared to 23503 for fake news. The open-source Kaggle dataset, which was selected for the project, served as the source of both datasets. The results of the construction and comparison showed that the decision tree model did the best forecasting with a maximum accuracy of 99.64% and the random forest model performed well with an accuracy of 98.89%. However, the logistic regression model did well in this assignment with an accuracy of 98.88%. Using these models has the critical goal of improving the news verification system's accuracy and dependability. Keyword: Fake news, Verification System, Machine Learning Model. Proceedings Citation Format Adeola, O.O., Bello, G.R. Oluwasola, B.S. & Lateef, K.R. (2023): Development of a Fake News Detection Model Using Decision Tree. Proceedings of the Cyber Secure Nigeria Conference. Nigerian Army Resource Centre (NARC) Abuja, Nigeria. 11-12th July, 2023. Pp 81-88. https://www.csean.org.ng/. dx.doi.org/10.22624/AIMS/CSEAN-SMART2023P10
Addressing the Dilemma of a “Crisis within a crisis”: Exploring the Penetration Testing challenges in a Mobile Field Hospital Setting
Authors:   IMT Mines Ales, South France, Ahmed N.B. , Daclin N. , Olivaux M. , Dusserre G.
Published: July 2023

This paper focuses on evaluating the security challenges faced by mobile field hospitals, which play a crucial role in emergency response and disaster management in remote and austere environments. The authors conducted a penetration test using the Open Source Security Testing Methodology Manual (OSSTMM) framework to assess the security posture of a mobile field hospital. The methodology employed in the study included a combination of automated and manual techniques such as network scanning, vulnerability assessments, social engineering, and exploitation. The penetration test revealed several security vulnerabilities in the mobile field hospital, including weak passwords, unpatched software, and inadequate network segmentation. Additionally, the study identified vulnerabilities in the hospital's medical devices and equipment, posing a risk of cyber-attacks that could disrupt operations and compromise patient safety. The results underscore the importance of implementing enhanced security measures in mobile field hospitals to mitigate cyber threats and ensure the uninterrupted functioning of medical operations during emergencies and disasters. This study provides a comprehensive analysis of the mobile field hospital's security posture using the OSSTMM framework and emphasizes the urgent need for improved security practices in such settings. Keywords: Cybersecurity, Healthcare, Penetration Testing, Mobile Field Hospitals, Data, Emergency Response, Open Source, Security Testing, Ethical Hacking, Security Frameworks, Proceedings Citation Format Ahmed, N.B., Daclin, N., Olivaux, M. & 4usserre, G. (2023): Addressing the Dilemma of a “Crisis within a crisis”: Exploring the Penetration Testing challenges in a Mobile Field Hospital Setting. Proceedings of the Cyber Secure Nigeria Conference. Nigerian Army Resource Centre (NARC) Abuja, Nigeria. 11-12th July, 2023. Pp 67-80 https://www.csean.org.ng/. dx.doi.org/10.22624/AIMS/CSEAN-SMART2023P9
Auditor Materiality Threshold and Audit Quality—Evidence from the Revised ISA 700 in the United Kingdom
Authors: Goh Beng Wee , Lee Jimmy , Li Dan , Li Na , Wang Muzhi
Published: July 2023

SYNOPSIS

Using a broad sample of U.K. firms that are required to disclose auditor materiality thresholds under the International Standards on Auditing (United Kingdom and Ireland) 700, we examine whether the auditor materiality threshold is associated with audit quality. We document that a lower materiality threshold is associated with higher audit quality, as measured by lower absolute discretionary accruals, higher accruals quality, and a lower propensity to just meet or beat analysts’ earnings expectations. We also find some evidence that the negative association between the materiality threshold and audit quality is attenuated when the audit committee is more effective and when the auditor is more economically dependent on the client, and the negative association is more pronounced when management has a stronger incentive to manage earnings. Overall, our study extends the limited studies on large-sample archival evidence on the implications of audit materiality thresholds on audit outcomes.

Data Availability: Data are available from the public sources cited in the text.

JEL Classifications: M40; M41; M42.
The effect of grenz ray therapy on pustulosis palmoplantaris. A double-blind bilateral trial.
Authors: Lindelöf B , Beitner H
Published: July 2023

The effect of grenz ray therapy in the treatment of pustulosis palmoplantaris was assessed in 15 patients by randomly allocating active treatment of the lesions of one side of the body, while the lesions on the other side, which received stimulated therapy, served as a control. Four Gy of grenz rays 10 kV were applied on 6 occasions at intervals of 1 week. A significantly better therapeutic result was recorded on the lesions which had received active grenz ray therapy. However, the therapeutic response was moderate. It is concluded that grenz ray therapy could be useful in pustulosis palmoplantaris mainly as an adjunct to other therapies.
Deposits of immunoglobulins and complement C3 in clinically normal skin of patients with lupus erythematosus
Authors: Ullman S , Halberg P , Wolf-Jürgensen P.
Published: July 2023

Deposits of immunoglobulins and/or complement C3 were found in two-thirds of biopsies from clinically normal skin of 64 patients with systemic lupus erythematosus, as judged by well defined criteria. The incidence of deposits in clinically normal skin was identical in patients with and without clinical skin lesions. IgM was found more frequently in the deposits (88%) than was IgG (36%) but equally frequently in involved and uninvolved skin, whereas C3 was found more often in patients with skin lesions (59% in involved skin, 36% in uninvolved skin) than in patients without skin lesions (14%). The occurrence of IgG and IgA was less frequent than that of C3 but the distribution was similar to that of C3. In normal skin of 20 patients with chronic discoid LE, deposits were found in one. Deposits were found in the skin of one-third of patients with nuclear antibodies in their sera and symptoms compatible with SLE but with a score of symptoms too low to meet the criteria.
Diffuse hair loss and psychiatric disturbance
Authors: Eckert J.
Published: July 2023

32 women complaining of diffuse alopecia were assessed by a psychiatrist, and daily hair loss and root counts were measured and compared with control women. Seven of the 32 women had severe marital difficulties, and 2 of these were overtly depressed. In these 7 women, daily hair loss and telogen counts did not differ significantly from the values for control women, whereas the remaining 25 women had a significant increase in hair loss and telogen counts. It is suggested that those women whose complaint of hair loss seems disproportionate to the objective degree of alopecia should be questioned as to symptoms of depression and marital difficulties.
An in vivo and in vitro study of cell-mediated immunity in atopic dermatitis
Authors: Hovmark A.
Published: July 2023

Cell-mediated immunity was studied in patients with atopic dermatitis. Tuberculin skin tests were performed on 70 patients and on 18 controls. The patients with "severe dermatitis" and those with high IgE levels were hyporeactive. Lymphocyte transformation tests were carried out in 33 patients and 21 controls. This showed that the patients were hyporeactive to PPD and herpes simplex antigen and this was most prominent in the patients having high IgE values. However, there was no clear, statistically significant difference between patients and controls with regard to their in vitro response to PHA.