bluuebunny/crossref_metadata_2025 huggingface dataset:
Postpartum Haemorrhage Risk Prediction Model Developed by Machine Learning Algorithms: A Single-Centre Retrospective Analysis of Clinical Data
Authors: Wang Wenhuan , Liao Chanchan , Zhang Hongping , Hu Yanjun
Published: March 2024

Background: Postpartum haemorrhage (PPH) is a serious complication and a cause of maternal mortality after delivery. This study used machine learning algorithms and new feature selection methods to build an efficient PPH risk prediction model and provided new ideas and reference methods for PPH risk management. Methods: The clinical data of women who gave birth at Wenzhou People’s Hospital from 1 January 2021, to 30 March 2022, were retrospectively analysed, and the women were divided into a high haemorrhage group (337 patients) and a low haemorrhage group (431 patients) based on the amount of blood loss. Machine learning algorithms were used to identify the features associated with postpartum haemorrhage from multiple clinical variables using feature selection methods, such as recursive feature elimination (RFE), recursive feature elimination with cross-validation (RFECV), and SelectKBest, and to establish prediction models. Results: For all women, the features associated with postpartum haemorrhage were ‘age’, ‘newborn weight’, ‘gestational week’, ‘perineal laceration’, and ‘caesarean section’. The prediction model established by the random forest classifier performed best, with an F1 score of 0.73 and an area under the curve (AUC) of 0.84. For women who underwent caesarean section or had a vaginal delivery, the features associated with postpartum haemorrhage risk were different. The risk factors for postpartum haemorrhage in women who underwent caesarean section were ‘age’, ‘parity’, ‘preterm birth’, and ‘placenta previa’. The prediction model established by the random forest classifier performed best, with an F1 value of 0.96 and an AUC of 0.95. The risk factors for postpartum haemorrhage in women with vaginal delivery were ‘age’, ‘parity’, ‘gestational week’, ‘diabetes’, ‘assisted reproduction’, ‘hypertension (preeclampsia)’, and ‘multiple pregnancy’. The prediction model established by the AdaBoost classifier performed best, with an F1 value of 0.65 and an AUC of 0.76. Conclusions: Machine learning algorithms can effectively identify the features associated with postpartum haemorrhage risk from clinical variables and establish accurate prediction models, offering a novel approach for clinicians to assess the risk of and prevent postpartum haemorrhage.
SPARC is a Novel Prognostic Biomarker for Ovarian Cancer and Associated with Immune Signatures and Drug Response
Authors: Guo Xiaorong , Tai Huilin , Li Xiaoqing , Liu Peng , Liu Jin , Yu Shan
Published: March 2024

Background: The calcium-binding matricellular glycoprotein (SPARC, secreted protein, acidic and rich in cysteine) belongs to the extracellular-matrix-protein family, and its functions mainly focus on tissue injury, remodeling, and tumorigenesis. The role of SPARC in ovarian cancer remains controversial at present. Methods: We searched SPARC using The Cancer Genome Atlas/Genotype-Tissue Expression (TCGA/GTEx) and other databases to analyze the relationship between its expression level and survival, immunity signatures, and chemical drug response, in ovarian cancer. Additionally, we overexpressed SPARC with plasmids in ovarian cancer SKOV3 and ID8 cell lines, then measured the effects of SPARC on the proliferation, migration, invasiveness, clonality, and stemness of ovarian cancer cells by Cell Counting Kit-8 (CCK8), Transwell, wound healing assay, adhesion assay, plate cloning assay, and soft agar spheroid formation in vitro. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses showed the potential signaling pathway for SPARC. Results: The higher expression of SPARC in ovarian cancer is related to more advanced tumor stage, poorer clinical survival, and worse chemical drug response, whereas it is positively correlated with immune signatures. For ovarian cancer phenotypes, higher SPARC expression level promotes cell proliferation, migration, colony formation, and spheroid formation. The GO and KEGG enrichment highlighted the potential molecular mechanisms for SPARC with PI3K-AKT and MAPK signaling regulation. Conclusions: SPARC promotes ovarian cancer progression through proliferation, migration, invasiveness, clonality, and stemness. A high level of expression of SPARC in ovarian cancer patients can be used as a marker of poor prognosis and poor drug response.
Risk Factors for Pfannenstiel Incisional Hernia Following Cesarean Delivery and Outcomes after Laparoscopic and Open Surgical Repair
Authors: Sakoglu Nevin , Firat Aysun
Published: March 2024

Background: To analyse risk factors for cesarean section (CS)-induced incisional hernia in reproductive-aged women. Outcomes of minimal invasive herniorrhaphy and open technique were presented. Methods: Records of patients with Pfannenstiel hernia between 2010 and 2022 were reviewed. Risk factors for incisional hernia were evaluated with surgical outcomes. Results: 76 patients were included. Mean age was 46 ± 8.1 years. Bulging (81.5%), pain or discomfort (57.8%) and distention (31.5%) were the most common symptoms. We combined ultrasonography (90.7%) with contrasted tomography (71%) or magnetic resonance imaging (30%) for surgical planning. Risk factors were found as multiple previous CSs, local wound complications such as seroma, hematoma or abscess, body mass index >25, smoking, pregnancy-induced diabetes mellitus, emergency CS, and inadequate surgical technique (each, p < 0.05). In open technique (51.3%), fascia was closed by polydioxanone suture, with onlay mesh fixation. In laparoscopic hernioplasty (48.6%), tacker was used for mesh reinforcement. There was no bowel injury. Early complications were seroma and infection (p < 0.01 and p < 0.05, respectively). Most significant late complication was recurrence (7.8%). Conclusions: Clinicians should be ready to encounter more reproductive aged women with incisional hernia, since worldwide CS rate continues to rise. Awareness of risk factors, imaging methods, surgical options and outcomes are of great importance.
Epidemiology of Periodontitis in Pregnancy and its Impact on Pregnancy Outcomes following Basic Periodontal Treatment: A Prospective Cohort Study
Authors: Cai Qi , Cheng Haiying , Liao Jiajun , Yang Shaowei , Zhou Dongyan , Sheng Jian
Published: March 2024

Background: This study aimed to investigate the detection of periodontal indicators in pregnant women with periodontal disease and its impact on pregnancy outcomes. Our goal is to provide guidance for the clinical diagnosis and outcome prognosis evaluation for pregnant patients. Methods: From August 2020 to February 2021, we conducted a study to investigate the detection of periodontal indicators in pregnant women with periodontal disease and its impact on pregnancy outcomes. A total of 84 pregnant women with periodontal disease were selected as the experimental group, while 86 pregnant women with normal periodontal health during pregnancy were selected as the control group. The general data of the women in both groups postpartum were similar. We measured the volume of gingival crevicular fluid (GCF) obtained and determined the concentration of interleukin-1 beta (IL-1β) in the GCF. This research aimed to provide guidance for clinical diagnosis and pregnancy outcome prognosis. Results: The experimental group exhibited significantly higher levels of periodontal indicators such as the Simplified Oral Hygiene Index (sulcus bleeding index, SBI), probing depth (PD), and Oral Hygiene Index-Simplified (OHI-S) compared to the control group. Conversely, the clinical attachment levels (CAL) in the experimental group were significantly lower than those in the control group. Additionally, the IL-1β levels and GCF levels in the experimental group were significantly higher than those in the control group. Furthermore, the incidence of adverse pregnancy outcomes in the experimental group was 2 patients (2.38%), which was significantly lower compared to the control group where it was 13 (15.11%). The adverse pregnancy outcomes included amniotic fluid contamination, premature delivery, and low body weight. Conclusions: We observed that periodontal indicators, including OHI-S, CAL, SBI, and PD, were significantly elevated in pregnant women with periodontal disease. Additionally, we found that IL-1β levels had a substantial influence on pregnancy outcomes, such as amniotic fluid contamination, premature delivery, and low birth weight.
Cancer Therapy-Associated Pulmonary Hypertension and Right Ventricular Dysfunction: Etiologies and Prognostic Implications
Authors: Leiva Orly , Beaty William , Soo Steven , Agarwal Manyoo A. , Yang Eric H.
Published: March 2024

Advances in cancer therapies have improved oncologic outcomes but can potentially expose patients to risk of cardiovascular toxicity. While left ventricular (LV) dysfunction is a well-known cardiotoxicity of cancer therapy. Pulmonary hypertension (PH) and right ventricular (RV) dysfunction are seen with several cancer therapies, including alkylating agents, tyrosine kinase inhibitors (TKIs), and immunotherapy, and are associated with significant morbidity and mortality. Awareness and recognition of cancer therapy-associated PH and RV dysfunction is critical to identify underlying etiologies and institute the appropriate therapy. However, gaps exist in the current literature on the epidemiology of PH and RV dysfunction in cancer, underlying pathophysiology and optimal management strategies.
Efficacy and Safety of Deferred Stenting in Geriatric Patients with STEMI and High Thrombus Burden
Authors: Liu Ruifang , Xu Fangxing , Liu Tongku , Zhou Yujie , Wu Xiaofan
Published: March 2024

Background: Deferred stenting has been recognized as beneficial for patients with acute ST-segment elevation myocardial infarction (STEMI) accompanied by a high thrombus burden. Nevertheless, its efficacy and safety specifically in geriatric STEMI patients remain to be elucidated. This study aims to bridge this knowledge gap and assess the potential advantages of deferred stenting in an older patient cohort. Methods: In this study, 208 geriatric patients (aged ≥80 years) with STEMI and a high thrombus burden in the infarct-related artery (IRA) were enrolled. They were categorized into two groups: the deferred stenting group, where stent implantation was conducted after 7–8 days of continuous antithrombotic therapy, and the immediate stenting group, where stent implantation was performed immediately. Results: In the deferred stenting group, the stents used were significantly larger in diameter and shorter in length compared to those in the immediate stenting group (p < 0.05). This group also exhibited a lower incidence of distal embolism in the IRA, and higher rates of the thrombolysis in myocardial infarction (TIMI) blood flow grade 3 and myocardial blush grade 3 (p < 0.05). Additionally, the left ventricular ejection fractions at the 1-year follow-up were significantly higher in the deferred stenting group than in the immediate stenting group (p < 0.05). The rate of the major adverse cardiac events in the deferred stenting group was significantly lower than in the immediate stenting groups (p < 0.05). Conclusions: Deferred stenting for geriatric patients with STEMI and high thrombus burden demonstrates significant clinical benefits. This approach not only reduces the incidence of distal embolism in the IRA, but also enhances myocardial tissue perfusion and preserves cardiac ejection function. Moreover, deferred stenting has proven to be safe in this patient population, indicating its potential as a preferred treatment strategy in such cases.
Association between the Albumin-to-Globulin Ratio and Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy
Authors: Yuan Zhongyu , Zhang Ke , Li Haiwei , Wang Shengwei , Li Xiaoyan , Sun Weiping , Hang Fei , Mei Yingchen , Han Rui , Wang Changhua , Lai Yongqiang , Wu Yongquan , Zhang Xiaoping
Published: March 2024

Background: Atrial fibrillation (AF), which occurs four to six times more frequently in hypertrophic cardiomyopathy (HCM) patients than in the general population, is the most common persistent arrhythmia and has a substantial therapeutic consequence. In HCM patients, there are currently no discovered signs that could be utilized to identify AF. Methods: From 2018 to 2022, 493 individuals with a continuous diagnosis of HCM were examined at Beijing Anzhen Hospital. AF was proven using routine electrocardiography (ECG), 24-hour Holter ECGs, or bedside ECGs. Echocardiography and blood tests were performed for all patients. Analysis and comparison of the traits were performed in HCM patients with AF (n = 77) and without AF (n = 416). Results: Age (p <0.001), prevalence of ventricular tachycardia (VT, p < 0.001), prevalence of pulmonary artery hypertension (p = 0.027), and albumin-to-globulin ratio (AGR, p = 0.046) were all significantly higher in patients with AF, compared to patients without AF. In multivariate logistic analysis, age (odds ratio [OR], 1.063; 95% confidence interval [CI], 1.032–1.095; p < 0.001), history of VT (OR, 2.702; 95% CI, 1.007–7.255; p = 0.048), AGR (OR, 3.477; 95% CI, 1.417–8.536; p = 0.007), left atrial diameter (OR, 1.132; 95% CI, 1.073–1.194; p < 0.001), left ventricular end-diastolic diameter (OR, 0.861; 95% CI, 0.762–0.974; p = 0.017), left ventricular end-systolic diameter (OR, 1.239; 95% CI, 1.083–1.417; p = 0.002), and peak A wave velocity (OR, 0.983; 95% CI, 0.972–0.994; p = 0.002) were independently associated with AF in HCM patients. In the receiver operating characteristic curve analysis, the area under the curve for the established model was 0.819 (95% CI, 0.755–0.883, p = 0.033), with a sensitivity and specificity of 0.763 and 0.816, respectively, for AF occurrence in HCM patients. Conclusions: In individuals with HCM, a history of VT and a higher AGR are independently linked to AF. Further investigation is necessary to determine whether increased AGR represents a risk factor for embolic stroke or cardiovascular death.
Severe Aortic Stenosis Associated with Other Valve Diseases: Open Surgery or Percutaneous Treatment?
Authors: Moral Sergio , Abulí Marc , Ballesteros Esther , Vilardell Pau , Gutiérrez Laura , Brugada Ramon
Published: March 2024

Treatment decisions in the context of severe aortic stenosis (AS) associated with other valvular heart diseases (VHDs) have become a major challenge in recent years. Transcatheter aortic valve replacement (TAVR) in AS has increased significantly in younger patients with lower surgical risk, which has complicated the choice of the best treatment in cases of other associated valvulopathies. The most frequently associated lesions in this clinical scenario are mitral regurgitation (MR), mitral stenosis, and tricuspid regurgitation (TR). Furthermore, it should be noted that different percutaneous techniques are now available to accommodate any associated valvulopathies, which has considerably broadened the range of therapeutic options. The management of AS treated in isolation, especially by TAVR, has also shown that many cases of significant MR or TR are substantially reduced without any intervention. However, although some parameters have been described as potential risk factors in predicting the poor outcome of untreated VHDs, which cases will progress in a clinically more aggressive way remains uncertain. This review aimed to evaluate the most recent publications to provide the pathophysiology and prognosis of severe AS associated with other significant VHDs and to evaluate the best invasive therapeutic approach depending on the associated valvular disease.
Chronic constipation in children: diagnosis and treatment through the prism of time
Authors: Goryacheva O. A. , Tsvetkova L. N. , Moiseev A. B. , Khavkin A. I.
Published: March 2024

Constipation is one of the most frequent nosologies encountered during outpatient consultations with a pediatric gastroenterologist. This article discusses the diagnosis and treatment of chronic constipation (CC) in children on the basis of both international and Russian clinical guidelines. About 70% of children in the world suffer from CC, most of them have functional nature. In 30-52% of children, symptoms persist for the next 5 years, and about 25% of patients continue to suffer from constipation as adults. Children with CC often see a pediatrician and gastroenterologist, are treated as inpatients, or are hospitalized on an emergency basis. Consequently, chronic constipation represents a significant economic problem for the health care system. Constipation in children needs timely diagnosis and comprehensive treatment.
Foreign bodies of the stomach with the introduction into the mucous membrane of a 9-year-old child
Authors: Bokova T. A. , Koshurnikova A. S. , Shishulina E. E.
Published: March 2024

A description of the clinical observation of a 9-year-old child with foreign bodies of the stomach (2 magnetic balls) and their introduction into the mucous membrane is presented. Timely endoscopic and X-ray examinations contributed to the establishment of the exact localization of foreign objects, and videoesophagogastroscopy using a magnetic extractor made it possible to extract magnets from the mucous membrane with minimal damage to the stomach tissues and prevent the development of complications in this patient.
The debut of autoimmune hepatitis after a new coronavirus infection (COVID-19) in an 11-month-old child
Authors: Lebedeva T. N. , Marchukova A. Yu. , Bondar K. G.
Published: March 2024

In many countries fix cases of severe liver damage in children are recorded. A previous or existing coronavirus infection leads to a disruption in the body’s immune response to infections, which can lead to severe inflammation that caused liver damage. This article describes a clinical case of type 2 autoimmune hepatitis, a high degree of biochemical activity, that debuted in an 11-month-old child after a new coronavirus infection (COVID-19). The presented clinical example demonstrates the need for a thorough and comprehensive examination of children with the first clinical manifestations of liver damage and timely prescription of therapy
Semi-quantitative assessment of Helicobacter pylori by rapid urease tests in pediatrics
Authors: Kornienko E. A. , Kolomina E. O. , Parolova N. I. , Ermakov S. S. , Babaeva U. M. , Gladyshev N. S. , Svarval A. V. , Shchederkina E. E.
Published: March 2024

The study is devoted to the comparison of the results of rapid urease tests (RUT) and the data obtained in histological examination. For this purpose, the semi-quantitative assessment of urease activity of two BUTs was compared: the semi-quantitative Pronto Dry (GASTREX, France) widely used in Europe and the AMA RUT Expert M test registered in Russia (AMA LLC, Russia) with the data obtained by histological and PCR analyses. High correlation of semi-quantitative indices of urease activity according to the results of both tests as well as correlation of these indices with the data obtained by histological examination and PCR analysis was established.
Investigation of PWM methods for a 9 level boost inverter using CD-type carriers
Authors: R Sindhuja , S Padma , KRİSHNAN Suresh , EZHİLVANNAN Parimalasundar , HEMANTH KUMAR B
Published: March 2024

The article suggests a new boost inverter topology that uses two switching capacitors and a single dc source to produce an output voltage waveform with nine levels. There are no sensors or other electronics required because the capacitor voltages balance themselves. An input dc boost converter is not necessary when using an inverter because its output voltage is frequently two times greater than its input voltage, especially when the inverter is powered by a natural source. The new modulation techniques that have been proposed for CD-type carrier waves have better efficiency, higher RMS voltage, and less harmonic distortion (THD).The efficacy of the suggested carriers has been confirmed by phase disposition (PD), alternate phase opposition disposition (APOD), and phase opposition disposition (POD) investigations. The effectiveness of each technique described under 9LBI has been evaluated using a MATLAB/Simulink configuration. The operation and dynamic performance of the suggested architecture have been modelled using MATLAB/ SIMULINK.
The Effects of the Unequal Rotor Slot Arc on Cogging Torque for Flux Switching Permanent Magnet Machines
Authors: ÇETİN Emrah
Published: March 2024

Many of the electric machine researchers are studying the Flux switching permanent magnet (FSPM) machines. The cogging torque is one of the most unwanted parameter for highly sensitive electric machine applications. In this study, the configuration of the unequal rotor slot arc (URSA) to see the effects of the asymmetry for three phase FSPM machine has been studied. The proposed asymmetry contains of presenting different arc angled rotor poles and analyzing the torque performance of them by using 2D finite element analysis (2D-FEA). 12-stator pole/ 10-rotor pole (12s/10p) FSPM machine topology has been chosen for the design. Results proved that unequal rotor slot arc proposition demonstrate good performance in comparison to the symmetric design. Inequality on the rotor slots were simulated by using parametric analysis to minimize the cogging torque. The suggested design indicates a substantial reduction in cogging torque, achieving a conspicuous minimization. Consequently, the suggested using unequal rotor slot arc for FSPM machine has reasonable outcomes.
Formation of Basson Classes at the Paris Conservatory
Authors: Nechesnyi Ihor
Published: March 2024

The object of the study was the origins and initial period of the formation of bassoon classes at the Paris Conservatory. The author analyzed the early stages of the training process involved in the French bassoon school. The role of maîtrise and military bands in the instruction of bassoon performers before the beginning of the revolutionary events in 1789 was revealed. The study exposed the influence of the church music-educational system on the professionalization of secular instrumental and vocal performance, as well as its importance in the creative development of prominent French bassoonists who were formed in the second half of the 18th and early 19th centuries. The author investigated the essence of the ideological and political factors of the French Revolution in the creation of a new democratic system that began to exist in professional musical education, which guaranteed its accessibility to the general population and free education on a competitive basis. The article provides a chronology of the beginning and development of bassoon classes on the path of professionalization of performance on wind instruments at the National Guard Music School, the National Institute of Music and the Paris Conservatory. The peculiarities of the implementation of the competitive system of professional training of instrumentalists, as well as the formation of didactic materials to ensure the educational process at the Paris Conservatory became the basis for further artistic education. This fact was carefully analyzed and became the basis for the conclusions of the article. The innovative guide of E. Ozi "School of Playing the Bassoon", was regarded as one of the first complete instructional materials for the bassoon. It was officially approved as a study guide for mastering the instrument, became a powerful impetus for the development of the conservatory students’ performance skills. The author emphasized and defined the role of E. Ozi in the creation of bassoon classes at the Paris Conservatory, as well as in the founding of the French performing school. It has been proven that an important factor in the development of French bassoon performance in the second half of the 18th century was the inclusion of the bassoon in the training programs of metris and its use in church ensembles to accompany choral singing during divine services
МОЖЛИВОСТІ РІВНОВАГИ МІЖ РАЦІОНАЛЬНИМИ ТА ДУХОВНИМИ ВИМІРАМИ ЛЮДИНИ
Authors: Легкун Тетяна Василівна
Published: March 2024

Якщо розглядати окремі напрями сучасної філософії, то особливий інтерес викликають зміни та перетворення, які відбуваються в релігійній філософії. Частково процес еволюції релігійної філософії кінця XX ст. – початку XXI ст. можна пояснити тим, що на фоні прискорення соціальної динаміки все більш проблематичними постають як людська індивідуальність, так і життєва доля окремої людини. Науковий прогрес дозволяє побачити людину складнішою, ніж це уявлялося раніше: людина не зводиться до природного еволюційного процесу, а виявляє себе унікальним явищем дійсності. У зв’язку з цим людські погляди мимоволі звертаються і до релігії, оскільки релігійне бачення дійсності з його трансценденталізмом дозволяє побачити її залученою до особливих, найперших та вихідних засад буття. Вчені й представники церкви і релігії почали ставити цілу низку питань. Головне з них полягає в такому: чи не прийшов час, поки ще не пізно, розгорнути співпрацю з метою відновлення рівноваги між людиною і природою? чи не пора активізувати зусилля заради розумного і мудрого управління світом, виступити разом проти сцієнтистської політики, спробувати повернути рівновагу між раціональними і духовними вимірами людини? Власне, це ми і спробуємо з’ясувати у нашій розвідці.
ФІЛОСОФСЬКІ ЗАСАДИ ДЕЦЕНТРАЛІЗАЦІЇ: ПОНЯТТЯ Й КОНЦЕПЦІЇ
Authors: Радуцький Олександр Романович
Published: March 2024

Упродовж усієї історії стародавніх імперій, середньовічних королівств і сучасних держав завжди виникало питання, якому рівню влади треба довірити повноваження зі збору податків та ухвалення рішень і наскільки ці повноваження мають залишатися на центральному рівні чи бути делеговані місцевим органам влади. Децентралізація – це спосіб наблизити владу до громадян і забезпечити їхню активну участь в управлінні. Мета статті – розглянути концепції та філософські принципи, що лежать в основі децентралізації, щоб краще зрозуміти її філософську основу. Децентралізацію розглядають як систему управління, у якій розширюються повноваження органів влади нижчого рівня, а деякі функції, які раніше належали центральному уряду, будуть передані органам місцевого самоврядування. Проаналізовано різноманітні підходи й концепції, що визначають роль і цілі децентралізації в управлінні та суспільному розвитку. Визначено, що загальний зміст децентралізації визначається трьома характеристиками: децентралізація, делегування й передача повноважень. Детально розглянуто кожне із цих понять. Визначено основні принципи, що лежать в основі концепції децентралізації, до яких належать принципи однаковості й інституціоналізму, субсидіарності, взаємодоповнюваності, демократії та ресурсного забезпечення. Ключовим із-поміж цих принципів є принцип субсидіарності, який безпосередньо пов’язаний із місцевим самоврядуванням і включає процедури розподілу й перерозподілу повноважень між адміністративними рівнями. Ці принципи призводять до створення більш збалансованої та демократичної адміністративної системи. Досліджено роль системи місцевого самоврядування в Україні в умовах повномасштабного російського вторгнення. Досвід функціонування громад в умовах воєнного стану в Україні підтверджує як самостійність громад в ухваленні ключових рішень, так і необхідність легітимного контролю центральної влади над усіма місцевими процесами. Децентралізована система забезпечує належний захист інтересів населення завдяки функціям і повноваженням органів місцевого самоврядування.
«ГІБРИДНИЙ» ОБ’ЄКТ У МУЗЕЙНОМУ ПРОСТОРІ. ПОТЕНЦІАЛ ДЛЯ «ПРИМИРЕННЯ» МНОЖИННИХ НАРАТИВІВ
Authors: Геращенко Олеся Олексіївна
Published: March 2024

У рамках здійснення культурологічного аналізу миротворчої функції мистецтва, що актуалізується в постконфліктних середовищах у ХХІ столітті, авторка розглядає потенціал проєктування музейного простору для реалізації різних стратегій інтерпретації соціального та культурного досвіду, щоб у взаємодії історії, психології, культурології, мистецтва знайти такі форми організаційної діяльності музеїв, які б відповідали майбутнім суспільним викликам. Сучасні музейні практики зазвичай містять комбінацію кураторських підходів. Дві принципові актуальні парадигми музейних практик, передбачають, по-перше, історичну модель, що ґрунтується на процесах міграції, культурної передачі, гібридизації форми. Друга модель – естетична або формальна – надає пріоритетності іконографії та візуальній формі перед історичним контекстом. У спробі поєднати ідею універсальності з новішим дискурсом про глобалізацію, багато музеїв звертаються до обох підходів, розташовуючи роботи відповідно до культурної традиції і водночас до історичного наративу, підсилюючи взаємний вплив ще й спорідненістю форм. Розміщуючи мистецькі артефакти, які походять із різних регіонів у музейній залі, наче на великій сцені, можна створювати діалог культур. До цього рухаються всі значні музеї.
КУЛЬТУРНА ПАМ’ЯТЬ ПРО ГОЛОКОСТ У СОЦІАЛЬНИХ МЕРЕЖАХ INSTAGRAM І TIKTOK
Authors: Шарпило Марина Юріївна
Published: March 2024

Популярність соціальних мереж, що зростає, зумовила їх вплив на соціум і динаміку сучасної культури. Застосунки мають змогу створювати тенденції, даючи можливість кожному користувачеві до цього доєднатися. Завдяки медіапродукту платформи трансформують розуміння наративних подій, таких як Голокост. Саме інформативна наповненість застосунків дає змогу простежити, як саме відтворюється культурна пам’ять про подію минулого. У статті виокремлюються соціальні мережі Instagram і ТікТок, бо саме вони мають показовий візуальний матеріал, що висвітлює єврейську трагедію. Дослідження має на меті визначити й прослідкувати вплив застосунків на адаптацію культурної пам’яті про Голокост серед користувачів. Методологія ґрунтується на використанні культурологічного підходу до визначення специфіки сучасної культури та соціальних медіа; базується на методі контент-аналізу, за допомогою якого розглянуто особливості репрезентації Голокосту через призму візуального продукту. На основі перегляду показових прикладів контенту ми зафіксували моменти трансформації сприйняття єврейської трагедії аудиторією; за допомогою структурного методу визначили співвідношення індивідуальної та колективної рефлексії на подію в межах зазначених соціальних мереж. Наукова новизна отриманих результатів полягає в тому, що вперше подано аналіз контенту Instagram і TikTok про Голокост. Він дає змогу розширити уявлення про те, як трансформується культурна пам’ять про подію. Ми довели, що поряд із традиційними комеморативними практиками1 Голокост потребує сучасного осмислення за допомогою цифрового інструменту. Це дає можливість підлаштувати трагедію під такі запити суспільства, як доступність та інформативність.
ДЕРЖАВНІ МИСТЕЦЬКІ ЛІЦЕЇ: ҐЕНЕЗА ТА СУЧАСНІ КУЛЬТУРОТВОРЧІ ПРОЦЕСИ
Authors: Шумейко Людмила Михайлівна
Published: March 2024

У статті розглянуто історичні, законодавчі та культурологічні аспекти зародження, становлення й розвитку державних мистецьких ліцеїв, які в період із 60-х років ХХ століття до 2020 року мали назву «середні спеціалізовані мистецькі школи-інтернати». Розглянуто витоки та ключові етапи формування закладів, їх визначну роль у розвитку й підтримці реалізації потенціалу обдарованої молоді в галузі культури й мистецтва. Методологія дослідження передбачала використання сукупності методів і підходів: аналітичного, культурологічного, історико-ретроспективного, системного, що дало змогу комплексно дослідити означену проблематику й отримати обґрунтовані результати дослідження. Виокремлено та систематизовано 6 мистецьких ліцеїв, які юридично підпорядковані Міністерству освіти й науки та Міністерству культури та інформаційної політики України. Визначено головні особливості державних мистецьких ліцеїв. Стаття зосереджується на ґенезі освітньої політики України у сфері освіти й культури. На основі детального аналізу суттєвих змін у законодавчій базі за часів незалежності, періодів реформування системи мистецької освіти, зумовлених процесами євроінтеграції, виявлено їх вплив на розвиток державних мистецьких ліцеїв. У дослідженні приділено увагу сучасному стану державних мистецьких ліцеїв, їх завданням та особливостям функціонування в період геополітичних змін і викликів сучасності. Наукова новизна роботи полягає в систематизації вітчизняних профільних мистецько-освітніх закладів для обдарованих дітей, а також визначенні їх культуротворчого складника в системі мистецької освіти України.
O Arduino como recurso tecnológico para explicitação de invariantes operatórios relacionados à Teoria da Relatividade
Authors: Delgado Patrick Luiz Guevara , Calheiro Lisiane Barcellos , Gonçalves Além-Mar Bernardes
Published: March 2024

O avanço das tecnologias nas últimas décadas tem feito com que os aparatos tecnológicos se tornem cada vez mais presentes na sociedade. Dentre os diversos dispositivos presentes no mundo contemporâneo, o GPS (Global Positioning System) se apresenta como um recurso de extrema importância em áreas como a aviação e o transporte de mercadorias. Esse dispositivo possui fortes bases na teoria da relatividade restrita, devido à diferença de velocidade entre os satélites em órbita e os receptores localizados na superfície terrestre, ocasionando em uma dilatação temporal. Este trabalho desenvolveu um produto tecnológico, de cunho pedagógico, utilizando a Aprendizagem Baseada em Projetos (ABP) como referencial metodológico, com o objetivo de responder a seguinte questão de pesquisa: Quais invariantes operatórios relacionados à Teoria da Relatividade Restrita podem ser mobilizados por meio de uma atividade investigativa, tendo a aprendizagem baseada em projetos como referencial metodológico? Para análise dos dados, utilizamos a Teoria dos Campos Conceituais (TCC) desenvolvida por Gerard Vergnaud. A pesquisa foi implementada em uma turma de terceiro ano do ensino médio com um grupo de 20 estudantes em uma escola pública. Os resultados demonstram que, aliado à metodologia da ABP, o produto tecnológico se apresentou como um recurso pedagógico significativo, mobilizando diversos grupos de invariantes operatórios, alguns explícitos, outros implícitos, indo assim ao encontro da TCC, possibilitando uma demonstração dos efeitos relativísticos no cotidiano. Por fim, acreditamos que esta pesquisa venha favorecer a prática pedagógica do professor e o processo de aprendizagem dos estudantes.
Načrtovalnik poti za javni potniški promet in storitve mikromobilnosti
Authors: Frangež Miha , Pesek Matevž
Published: March 2024

V luči trenutne okoljske in energetske krize je uporaba javnega in nizkoogljičnega prevoza ključnega pomena za dosego zadanih državnih in evropskih ciljev do konca tekočega desetletja. Za razliko od osebnega avtomobila pa potovanje z drugimi načini prevoza zahteva vsaj nekaj načrtovanja, ki se lahko izkaže za preveliko prilagoditev za marsikaterega potencialnega uporabnika. Razlogi za nizko uporabo javnega prevoza in deljenih prevoznih sredstev ležijo v veliki meri v razdrobljenosti dostopa do informacij, potrebnih za njihovo učinkovito rabo. Cilj članka je načrtovanje poti olajšati z uvedbo inteligentnega načrtovalnika poti, ki na enem mestu omogoča samodejno iskanje možnosti prevoza in načrtovanje poti z več prevoznimi sredstvi z javno dostopnimi oblikami mobilnosti, kot so avtobusi, vlaki, souporabo avtomobilov in mestnimi kolesi. Problem rešujemo v treh korakih: (1) razvijemo enotni podatkovni model za podatke javnega prevoza in storitve mobilnosti v Sloveniji ter za vse ponudnike implementiramo adapterje iz posameznih zasebnih formatov v skupno strukturo, (2) postavimo odprtokodni multimodalni načrtovalnik poti OpenTripPlanner in (3) razvijemo hibridno spletno in mobilno aplikacijo, ki omogoča pregled nad vsemi podatki ter interakcijo z načrtovalnikom.
Manajemen Pembelajaran Terintegrasi dalam Model Pembelajaran Blended Learning, Learning Management System
Authors: Firman Muhammad , Berliana Berliana , Sauri R.Supyan , Wasliman Iim
Published: March 2024

The primary objective of this research is to examine the impact of the blended learning model based on the Learning Management System (LMS) on both student learning outcomes and motivation. Within the realm of education, students often encounter various challenges, such as a lack of enthusiasm, boredom, and difficulties in grasping learning materials due to the limited variety in teaching and learning approaches. To address these issues, this study adopts a survey method employing a quantitative approach. The study encompasses all students at STKIP PGRI Sukabumi, with a sample size of 100 students chosen through the Simple Random Sampling technique. Data collection is conducted via a questionnaire distributed through Google Forms. The analysis involves multiple linear regression utilizing the SPSS 23 program, and the findings are as follows: 1. The LMS-based blended learning model demonstrates a significant influence on learning outcomes, as indicated by the t-count value of 6.835, surpassing the t-table value of 1.984. 2. Learning motivation is identified as a significant factor affecting learning outcomes, with a t-count value of 10.216, exceeding the t-table value of 1.984. 3. Both the LMS-based blended learning model and learning motivation collectively exhibit a substantial impact on learning outcomes, evidenced by an F-count value of 59.851, surpassing the F-table value of 3.089. In summary, the study concludes that the integration of the LMS-based blended learning model and enhanced learning motivation plays a pivotal role in advancing student learning outcomes.
Quality Improvement Management in Teacher Professional Development
Authors: Isa Muhammad , Neliwati Neliwati , Hadijaya Yusuf
Published: March 2024

This research aims to evaluate the professional competence of elementary school teachers in Binjai City and the effectiveness of teacher quality management programs and related initiatives in raising teacher competency levels. The term for this kind of study is qualitative descriptive research, and it is a way of gathering information about the people and events studied via written or spoken descriptions. It is based on the individual's background as a whole (holistic) rather than isolating the individual and the organization into variables and examining them. in the context of the whole. Reading various written materials, looking at images, pondering about items, seeing individuals in their immediate environment via interviews, and other activities are all part of the qualitative research design. Qualitative methods are used in this study to obtain data. Researchers often use observation, document analysis, and interviewing in qualitative research as data collection methods. The study's findings demonstrate (1) That the Binjai City Public Elementary School instructors are qualified educators. The quality of instructional materials is correlated with the professionalism of teachers. Professional instructors construct high-quality education or learning processes for students to enjoy participating in the learning process and for school graduates to develop human resources of the highest caliber. (2) In general, educators at Binjai City Public Elementary Schools use a variety of instructional strategies, such as technology-based learning and cooperative learning. (3) Although cooperative learning and technology-based learning are the two learning methodologies that educators constantly use to carry out the teaching and learning process, many Binjai City Public Elementary School instructors have certifications and pursue further education.
Scout Extracurricular Curriculum Management in Improving Student Discipline in Madrasah
Authors: Bayu Astra Nurcholis Panji , Hafid Erwin , Suban Alwan
Published: March 2024

The phenomenon of a learning crisis occurred after the COVID-19 pandemic; discipline is one aspect that must be the main focus of schools during this learning crisis. At MTs Arifah, discipline is the primary goal of extracurricular scouting. This study aims to reveal curriculum management in improving student discipline in the scout extracurricular activities. This research also uses a descriptive qualitative approach to tell the facts of curriculum management of the scout extracurricular to improve student discipline. The results obtained from this study reveal that the management of scout extracurricular curriculum planning begins with preparing Prota and Promes as a reference for activities for one year and evaluations carried out by implicit means, namely oral reports by scout coaches to the principal; this evaluation is more effective because the principal is faster and understands the conditions of extracurricular scouting.
Review Article: Systemic Lupus Erythematosus in Gynecology
Authors: Franjić Siniša
Published: March 2024

The participation of the hypothalamic-hypophysial neurosecretory system (HHNS) in fish reproduction using light, electron microscopy and immunocytochemistry was established by ecologo-histophysiological studies for the first time in the world literature. At the beginning of passing fish migrations a violation of the HHNS basic osmoregulative function, causing habitat change is revealed. Simultaneously the HHNS causes the neurotropic effect on the central nervous system (CNS) arousal in the form of a dominant state of "Migration impulse." At the beginning of spawning, HHNS also initiates spawning behavior and completes it by participating in the body's protective-adaptive reactions to natural physiological stress. The functional role of the HHNS in fish reproduction is to initiate energy-intensive (reproductive) processes of migratory and spawning behaviors and to complete spawning by suppressing the hyperactivity of target glands, which ensures the body's transition to energy-saving plastic exchange. The analysis of the key role of the HHNS in the integration of fish reproduction by the self-regulation principle has allowed the development of a constructive working scheme. New biotech methods of managing breeding time, rates of survival and growth of valuable fish species were developed on this basis. They are presented in the form of 10 inventions. To stimulate sex maturation, drugs of isolated anterior and posterior pituitary lobes were developed and introduced in sturgeon industry, increasing the extent of their fish-breeding use by 15% and saving the pituitary up to 40%. To delay puberty, a method of industrial fish breeders reservation in the critical salinity habitat of 4-8‰, both in seawater and in table salt solutions has been developed. On this basis, a full-system method of sturgeon and salmon fish populations reproduction, covering all stages of farm biotechnology has been developed. It is carried out by mass breeders reservation in sea cages, obtaining there offspring and, after the river fish-farm growing youngs to their readiness for migration, the final cultivation them in sea cages gardens till large life-resistant youngs. For the implementation of the proposed industrial biotechnology and year-round fish farming a new installation of recirculating aquaculture systems (RAS) hatcheries and farms was developed by means of the off-season underground conditioning of fish cultivation habitat and by the principle of natural-industrial engineering ecology. Due to the general aim ‒ increasing the efficiency biotechnology of reproduction and logical relationships, all developments are integrated into the system of biotech management of fish population reproduction.
Comparative Characteristics of The Pool of Amino Acids in Partial Cerebral Ischemia and Subtotal cerebral Ischemia in Outbred White Rats
Authors: I. Bon Elizaveta
Published: March 2024

Cerebrovascular diseases are widespread throughout the world. In these diseases, the pool of amino acids in the brain changes. One-hour SCI is characterized by the following changes in the AAs pool: a decrease in the content of sulfur-containing AAs, with a decrease, in contrast to SCI, of both methionine and cysteate, as a reflection of a higher activity of oxidative stress in SCI. Along with this, in subtotal cerebral ischemia, as in PCI, an increase in the content of L-arginine, a tendency to an increase in the content of the inhibitory neurotransmitter glycine, and a decrease in aspartate and glutamate as AAs with the properties of excitatory neurotransmitters, as well as tryptophan, valine and leucine, were noted. At the same time, in contrast to PCI, there was no increase in the level of glutamate and a decrease in the levels of BCAAs. Studies of the pool of amino acids in PCI and SCI will serve as a fundamental basis for the development of methods for diagnosing and correcting cerebrovascular pathology.
Analisis Perbandingan Metode Harmonic Mean Filter dan Contraharmonic Mean Filter untuk mengurangi noise pada Citra Digital
Authors: Chairy Amalia , Arifin Nurhikmah , Insani Chairi Nur
Published: March 2024

The results of digital camera recordings to take digital images, there are often some disturbances that appear in the digital image called noise. The noise that is often found in digital images is Salt-Pepper Noise and Speckle Noise. An image that has noise usually occurs due to an error in image retrieval techniques. Noise that usually appears is spots on the image, it is necessary to reduce noise by using the right filter method so that the resulting image matches the original. One of the filter methods to reduce noise is the harmonic mean-filter and contra-harmonic mean filter methods. From the calculation results of the average Mean Square Error (MSE) and Peak Signal to Noise Ratio (PSNR), it can be concluded that the Harmonic Mean Filter method is better at reducing salt & pepper noise. While the Contra-Harmonic Mean Filter method is better at reducing speckle noise.
Evaluasi Tingkat Keberhasilan Pembelajaran Online dengan menggunakan Metode Fuzzy Mamdani
Authors: Ismail  , Sakina
Published: March 2024

Online learning is no longer a new thing for many schools today, online learning is a solution for schools, teachers and students to continue to carry out teaching and learning activities even though they are separated by distance. With this solution, it is also necessary to have an evaluation process to measure whether this method is really successful and feasible to use. SMK Negeri 1 Tapalang Barat is a school that still applies online learning to this day because the school building is still under renovation. However, the evaluation process of the learning process has never been carried out, departing from these problems, this study discusses the evaluation of the success rate of online learning using the Mamdani fuzzy method. The test subjects in this study were students of class XII Teknik Audio Video at SMK Negeri 1 Tapalang Barat, whose data were taken from school archives and the distribution of questionnaires to students and teacher responses to the evaluation system of online learning success rates were collected through questionnaires. The data that has been collected will be analyzed using a quantitative approach. The results showed that the system built to facilitate the school in evaluating student learning in online learning for class XII Teknik Audio Video at SMK Negeri 1 Tapalang Barat has been successfully tested and runs according to its functionality and has succeeded in meeting the needs of the school for the problems faced, both from the point of view of the authors and users who use the system, as well as the manual calculation of the mamdani fuzzy method has been successfully applied to the system.