bluuebunny/crossref_metadata_2025 huggingface dataset:
FORMAÇÃO E PRÁTICA DOCENTE EM SUAS MÚLTIPLAS DIMENSÕES
Authors: Melo Antonio de Freitas , Chiari Camila Maria , Aguiar Camile de Araujo , Rocha Cássia Victor , Gomes Cléo Ferreira , Silva Júnior Dilmar Rodrigues da , Nascimento Fabiana Alves do , Pereira Jaqueline Gomes , Silva Juarez Bento da , Silva Karina Machado da , Rohleder Leilane dos Santos , Machado Letícia Rocha , Bezerra Luzenir Medeiros , Lima Maria Divina Ferreira , Miranda Shirlane Maria Batista da Silva , Biléssimo Simone Meister Sommer , Maia Vitor
Published: September 2024

O presente e-book, intitulado FORMAÇÃO E PRÁTICA DOCENTE EM SUAS MÚLTIPLAS DIMENSÕES, foi organizado por professores que acreditam que a educação tem muito ainda para melhorar. Porém, longe de fazer terra arrasada, buscamos, a partir de pesquisas e pontos de vista variados pelos diversos envolvidos no processo educacional, construir uma base para que a educação brasileira possa usufruir dessas práticas.
Dessa forma, o e-book está separado com distintas áreas que envolvem todo o contexto educacional, a fim de englobar um grande número de tópicos relevantes de nossos tempos, que possuem ligação interna e que contribuem, a partir de singularidades, que o todo se transforme. Cada área escolhida possui grande relevância, estando em alta nos debates acadêmicos e sendo visualizados também no ambiente escolar, mesmo sabendo o distanciamento que por vezes existe entre a escola e a academia.
Acreditamos no papel do professor pesquisador, que, inserido em diferentes contextos, alia a teoria com a prática, o material com o imaterial e constrói uma nova forma de compreender o mundo e de transformar a realidade a partir de suas leituras e explorações. Esperamos que o presente e-book fortaleça o ambiente escolar e incentive as transformações sociais, o combate à desigualdade e a redução dos problemas que historicamente lutamos.
EDUCAÇÃO E SOCIEDADE: UM OLHAR TRANSDISCIPLINAR
Authors: Castro Alaides Vieira de Sousa , Sousa Antonia Daniela de , Sobrinho Benedito Braz , Vasconcelos Bianca Barros , Costa Camyla Silva da , Silva Daniel de Castro , Chaves Edmilson Rodrigues , Damasceno Ednacelí Abreu , Chaves Fabiana Maria Roque , Gomes Francisca Cibele da Silva , Braz Francisca de Fátima Lemos , Ferreira Francisco Hélio Damasceno , Xavier Francisco José Pinheiro , Oliveira Gabriel Frechiani de , Grotti Giane Lucélia , Dias Idalina Maria Sampaio da S. F. , Silva Joaklebio Alves da , Silva Filho José Amadeu da , Silva José Cristiano da , Almeida Josiane Marques Duarte , Sousa Juliana Veras de , Silva Kércia Demyles Justino da , Willima Kleverson Gonçalves , Souza Leonardo Pereira de , Couto Lívia Maria Albuquerque , Mendes Márcia Cristiane Ferreira , Gama Márcia Oliveira , Santos Marcos Vicente Miranda , Oliveira Maria de Lourdes Alves de , Souza Maria Tauane Pereira de , Veronese Naiana Cardoso Dourado , Barros Nephi Moraes de , Silva Nilton César Alves da , Penha Pedro Xavier da , Sousa Raimundo Expedito dos Santos , Sousa Regiswânia Seillane Rodrigues de , Alencar Rosilda Albuquerque , Fontenele Santana Miranda , Silva Soraia Dias de Brito e , Mororó Taynara Cid Timbó
Published: September 2024

A educação é um tema que atravessa séculos, culturas e sociedades, refletindo as diversas formas como os seres humanos se relacionam entre si e com o mundo. No entanto, em tempos de rápidas transformações sociais, ambientais e tecnológicas, torna-se cada vez mais evidente que a educação não pode ser compreendida apenas através de um único prisma. O livro: “Educação e Sociedade: um olhar transdisciplinar” surge como uma proposta ousada para desbravar as complexas interconexões entre educação e diferentes dimensões sociais, culturais, econômicas e ambientais.
Neste volume, o leitor encontrará uma coletânea de ensaios e pesquisas que abordam a educação sob uma perspectiva transdisciplinar, reconhecendo que os desafios contemporâneos exigem uma abordagem que transcende as fronteiras tradicionais do conhecimento. Os autores, provenientes de diversas áreas do saber, dialogam entre si e com as suas disciplinas, promovendo uma reflexão crítica sobre como a educação pode ser um agente de transformação social.
O DIREITO DA PESSOA IDOSA À EDUCAÇÃO E AS RELAÇÕES INTERGERACIONAIS: CAMINHOS PARA A INCLUSÃO EM UM CENTRO DE EDUCAÇÃO DE JOVENS E ADULTOS (CEJA) EM FORTALEZA
Authors: Assis Ana Claudia Lima de , Santos Verônica Lopes dos
Published: September 2024

Neste trabalho, discutimos a importância da efetivação do direito à educação para a pessoa idosa, a partir da oferta da modalidade educação de jovens e adultos no CEJA Prof. José Neudson Braga, numa perspectiva intergeracional. Partimos do princípio de que os CEJA constituem um espaço para a promoção de uma Educação Intergeracional por ser um ambiente escolar que oferta a escolarização para jovens a partir de 15 anos, adultos e idosos, e apresentar uma proposta regimental e estrutu- ral diferenciada, favorável à participação de alunos e alunas de todas as idades, inclusive as pessoas idosas.
COLETÂNEA INTERDISCIPLINAR DOS ESPAÇOS SURDOS
Authors: Anchieta Ester Vitória Basílio , Maciel Jonathan Uilian Silva , Rangel Lucas de Souza , Franco Jenifer da Motta , Silva Maysa Martins , Casimiro Julia Nascimento , Silva Layla Rodrigues da , Sousa Laura Lyssa Carvalho de , Tavares Letícia Prado , Castelló Ramiro Lourenço , Chaves Matheus de Lima , Santos Stephany Costa dos , Cavalcanti Hanny Beatriz de Brito , Santos Larissa Gonçalves dos , Miranda Aurenita Émile Sá , Nogueira Nícolas Chenquel , Figueiredo Lorrane dos Anjos , Guerra Cristiane Silva Ferreira , Lima Yasmin de Oliveira , Santos Lucas Bayma de Oliveira dos , Pinheiro Tainá Barcelos , Silva Jackson Menezes , Pinheiro Ivana Cristina de Lima
Published: September 2024

Como docentes, sempre lidamos com uma grande barreira ao solicitar um trabalho escrito. Essa barreira cresce ao pedirmos um artigo científico como trabalho de conclusão. A escrita científica, na maioria expressiva das vezes, é novidade para o alunado, sendo comumente permeada por inseguranças e desconhecimento. A disciplina de Língua Brasileira de Sinais (Libras) tornou-se obrigatória nas licenciaturas a partir da Lei Nº 10.436, de 24 de Abril de 2002. No Instituto Multidisciplinar de Química da UFRJ – Macaé, esta disciplina é ofertada na modalidade eletiva a todos os cursos, desde que haja sobra de vagas. Entendendo a importância da escrita científica no percurso acadêmico dos alunos dos cursos de licenciatura, a proposta de produzir os trabalhos aqui reunidos vai além do estímulo à escrita científica, sendo igualmente um instrumento para desmistificação desta modalidade e para instigar nos alunos um sentimento de desbravamento da produção de pesquisas. A presente obra foi concebida diante de artigos científicos especialmente selecionados pelo corpo editorial, ou seja, todos os discentes matriculados na disciplina de Libras em 2023.2 participaram das atividades de produção científica, mas apenas os trabalhos em destaque, nos quais as orientações foram seguidas de forma geral, estão sendo divulgados. Os conteúdos apresentam considerações pertinentes sobre os temas abordados frente ao meio de pesquisa e/ou objeto de estudo. Desta forma, esta publicação tem como um dos objetivos garantir a reunião e visibilidade destes conteúdos científicos por meio de um canal de comunicação preferível de muitos leitores. Este e-book, em sua segunda edição, conta com trabalhos científicos inter e multidisciplinares, aliados a temáticas das práticas ligadas à Surdez, bem como os aspectos que buscam estar em consonância com as contribuições de diversos autores. É possível verificar a utilização das metodologias de pesquisa aplicadas, assim como uma variedade de objetos de estudo.
A FALTA DE ACESSIBILIDADE AO SURDO NA ENGENHARIA CIVIL DA UFRJ-MACAÉ
Authors: Maciel Jonathan Uilian Silva , Rangel Lucas de Souza , Anchieta Ester Vitória Basílio
Published: September 2024

A falta de inclusão de pessoas Surdas nos meios sociais pode ser associada a diversos motivos, sendo assim, o objetivo deste artigo é abordar a falta de conhecimento da cultura Surda e de como esse problema pode prejudicar essa minoria da sociedade em sua formação e vida profissional. O tema “acessibilidade” tem se popularizado nos dias atuais e as leis de cotas tentam garantir esse direito às pessoas com deficiência, todavia, em grande parte das vezes a aplicabilidade dessa legislação pode resultar em uma experiência ruim para o cotista, principalmente se o objetivo das instituições é apenas preencher o número de vagas reservados pela lei. Com a ausência de uma transição adequada, o que era para ser “inclusão”, na grande maioria das vezes culmina em “exclusão”, por isso a importância de se construir, além de um ambiente acessível, uma sociedade inclusiva, pois não basta dar acesso, é necessário tornar os espaços inclusivos, a fim de que as pessoas com deficiência se sintam confortáveis e semelhantes ao seu próximo em todos os locais que elas queiram ou necessitem acessar.
TERMOS TÉCNICOS ESPECÍFICOS DA BIOLOGIA BILÍNGUE: BIOLOGIA E LIBRAS
Authors: Silva Jackson Menezes , Silva. Layla da
Published: September 2024

De acordo com a Constituição Brasileira, o ensino da Língua Brasileira de Sinais (Libras) é obrigatório como primeira língua oficial dos Surdos desde a educação infantil, enquanto o português deve ser adotado como segunda língua. posto isto, o presente estudo teve como objetivo fazer uma pesquisa bibliográfica de termos técnicos específicos da Biologia em Libras, comparando os sinais já existentes com possíveis novos sinais. Para ter um embasamento teórico relevante ao estudo foi utilizado um dicionário trilíngue e alguns artigos com relevância social, aplicabilidade e versatilidade de conteúdo abordado. Dessa forma foi possível observar a carência de muitos termos técnicos específicos da Biologia em Libras, no entanto, as pesquisas relacionadas ao tema vêm crescendo exacerbadamente. A popularização e a obrigatoriedade da Libras nos cursos de licenciatura vêm contribuindo para esse crescimento exacerbado, portanto, espera-se que com mais estudos na área essa disciplina venha abranger todos os cursos superiores.
COMPARATIVO DAS LÍNGUAS DE SINAIS EM PAÍSES LUSÓFONOS
Authors: Tavares Letícia Prado , Castelló Ramiro Lourenço , Silva. Layla Rodrigues da
Published: September 2024

Este artigo tem como objetivo evidenciar as diferenças e semelhanças das línguas de sinais dos países lusófonos, ou seja, da comunidade dos Países de Língua Portuguesa (CPLP), mais especificamente Angola, Brasil e Portugal. Para tanto, faz um passeio pela história da comunidade Surda, ressaltando sua cultura e vivências.
COMUNIDADE SURDA E SUA RELAÇÃO COM A RELIGIÃO CRISTÃ
Authors: Chaves Matheus de Lima , Santos Stephany Costa dos , Silva. Layla Rodrigues da
Published: September 2024

Mediante a importância da inclusão e da acessibilidade de Surdos, este artigo procura trazer a visão que a igreja e a sociedade possuem com relação à Surdez e à forma como é tratada. Também é apresentada como essa visão foi sendo moldada através de relatos históricos e estudos no decorrer dos anos. O objetivo do estudo é ampliar a visão e a fomentação de diálogos que promovam a importância de iniciativas e práticas de inclusão e compreensão em diferentes espaços, tomando a Igreja Batista como um exemplo analisado na providência de tornar a fé cristã não somente acessível, mas também acolhedora dos Surdos. Na abordagem dessa realidade levou-se em consideração propostas e sugestões, como o aumento de intérpretes nas igrejas e o incentivo ao envolvimento de líderes ouvintes com ministérios voltados para os Surdos, que visam melhorar e ampliar o relacionamento da comunidade Surda com a Religião Cristã, e promover maior disseminação do Evangelho.
Advancements in Clinical Research: Phases, Ethical Considerations, and Technological Innovations
Authors: Ashish Pandey
Published: September 2024

Background: Clinical research is a vital component of medical advancements, contributing to the discovery of new treatments, procedures, and health interventions. This paper discusses the importance of clinical trials, the structure and phases of trials, ethical considerations in research, and the role of modern technologies in reshaping clinical trials. Objective: This article aims to provide a comprehensive overview of the clinical trial process, ethical compliance, and the integration of technological advancements, with real-world examples and recent studies to support the discussion. Methods: The article provides a descriptive analysis of the different types of clinical research, the various phases of clinical trials, and ethical considerations based on established guidelines such as the Declaration of Helsinki and the Belmont Report. It also examines how recent technological innovations, including AI, wearable devices, and Electronic Health Records (EHRs), have revolutionized the field. Results: The integration of technology into clinical research has resulted in more efficient, data-driven, and patient-centric trials. Ethical compliance, guided by international regulations, remains a critical factor in ensuring patient safety and maintaining public trust in clinical research. Conclusion: The future of clinical research relies heavily on technological innovation and strict adherence to ethical guidelines. As new treatments and therapies emerge, the structure of trials and the responsible use of technology will play an essential role in shaping the future of healthcare.
Molecular Insights on Coffee Components as Chemical Antioxidants
Authors: Hernández-Ayala Luis Felipe , Guzmán-López Eduardo Gabriel , Pérez-González Adriana , Reina Miguel , Galano Annia
Published: September 2024

Coffee is not only a delicious beverage but also an important dietary source of natural antioxidants. We live in a world where it is impossible to avoid pollution, stress, food additives, radiation, and other sources of oxidants that eventually lead to severe health disorders. Fortunately, there are chemicals in our diet that counteract the hazards posed by the reactive species that trigger oxidative stress. They are usually referred to as antioxidants; some of them can be versatile compounds that exert such a role in many ways. This review summarizes, from a chemical point of view, the antioxidant effects of relevant molecules found in coffee. Their mechanisms of action, trends in activity, and the influence of media and pH in aqueous solutions, are analyzed. Structure-activity relationships are discussed, and the protective roles of these compounds are examined. A particular section is devoted to derivatives of some coffee components, and another one to their bioactivity. The data used in the analysis come from theoretical and computational protocols, which have been proven to be very useful in this context. Hopefully, the information provided here will pro-mote further investigations into the amazing chemistry contained in our morning coffee cup.
 
Resumen. El café no solo es una bebida deliciosa, sino también una importante fuente dietética de antioxidantes naturales. Vivimos en un mundo donde es imposible evitar la contaminación, el estrés, los aditivos alimentarios, la radiación y otras fuentes de oxidantes que eventualmente conducen a trastornos de salud graves. Afortunadamente, existen sustancias químicas en nuestra dieta que contrarrestan los peligros planteados por las especies reactivas que desencadenan el estrés oxidativo. Por lo general, se les denomina antioxidantes; algunos de ellos pueden ser compuestos versátiles que ejercen dicho papel de muchas maneras. Este artículo de revisión resume, desde un punto de vista químico, los efectos antioxidantes de moléculas relevantes encontradas en el café. Se analizan sus mecanismos de acción, tendencias en la actividad y la influencia del medio y el pH en soluciones acuosas. Se discuten las relaciones estructura-actividad, y se examinan los roles protectores de estos compuestos. Se dedica una sección particular a los derivados de algunos componentes del café, y otra a su bioactividad. Los datos utilizados en el análisis provienen de protocolos teóricos y computacionales, que han demostrado ser muy útiles en este contexto. Se espera que la información proporcionada aquí promueva investigaciones futuras sobre la química contenida en nuestra taza de café matutina.
Exploring Intermolecular and Intramolecular Interactions: A Review beyond Hydrogen Bonds
Authors: Vargas Rubicelia , Garza Jorge , Martínez Ana
Published: September 2024

Intermolecular interactions have great relevance in the stability of chemical systems. The most studied non-covalent interactions are hydrogen bonds, but they are not the only ones. Dihydrogen bonds or hydrogen - hydrogen contacts, as well as those that occur between heteroatoms, have also shown to play an important role in the molecular structure of biomolecules, solids, surfaces and other chemical systems. In this article we summarize the main contributions of our group to the study of these intermolecular interactions.
Among the most important results generated in our group is the estimation of the interaction energy of the unconventional hydrogen bond C-H•••O, which showed its relevance in various systems. In addition, software programmed on graphic processing units was created in our group to analyze electron density using the Quantum Theory of Atoms in Molecules (QTAIM). This code has allowed us to study non-covalent interactions in large systems.
 
Resumen. Las interacciones intermoleculares tienen una gran relevancia en la estabilidad de sistemas químicos. Las más estudiadas son los puentes de hidrógeno, pero no han sido las únicas. Los enlaces dihidrógeno o los contactos hidrógeno-hidrógeno, así como las interacciones que ocurren entre heteroátomos, también han mostrado un papel importante en la estructura molecular de biomoléculas, sólidos, superficies y otros sistemas químicos. En este artículo resumimos las principales contribuciones de nuestro grupo hacia el estudio de estas interacciones intermoleculares.
Entre los resultados más importantes generados por nuestro grupo es la estimación de la energía de interacción de puentes de hidrógeno no convencionales C-H•••O, los cuales han mostrado su relevancia en varios sistemas. Además, el código computacional programado sobre tarjetas gráficas creado en nuestro grupo permite analizar la densidad electrónica usando la teoría cuántica de átomos en moléculas (QTAIM). Este código computacional nos ha permitido estudiar interacciones no covalentes en sistemas de gran tamaño.
50 years of Chemistry at the Universidad Autónoma Metropolitana
Authors: Almanza-Pérez Julio César , Garza Jorge , González-Martínez Ignacio , Guzmán-González Gregorio , Ochoa-Tapia J. Alberto
Published: September 2024

Editorial of "50 years of Chemistry at the Universidad Autónoma Metropolitana"
As múltiplas faces da Infodemia
Authors: Gonçalves Luis , Castro Leonardo , Rachid Raquel , Fornazin Marcelo
Published: September 2024

Neste artigo, revisamos partes da literatura acadêmica sobre a infodemia buscando preencher uma lacuna de estudos que descrevam a sua existência político-econômica, científica, sociotécnica e psicossocial em geral, ao mesmo tempo em que verifiquem como essa imbricação se encontra com a realidade brasileira. Nesse enquadramento, a infodemia emergiu como uma superabundância problemática de informações sobre saúde, capaz de comprometer seus cuidados individuais e coletivos e que integra conflitos sócio-econômicos e culturais relacionados ao capitalismo neoliberal e periférico. Por isso, encontramos distintas e até antagônicas formas de caracterizar e enfrentar a infodemia. Algumas delas contrastam com os princípios do SUS e da reforma sanitária, especialmente com relação à participação política dos sujeitos atingidos pela infodemia enquanto uma forma de enfrentar o fenômeno e os conflitos de que ela faz parte. Concluímos que, enquanto um fenômeno multideterminado, a infodemia deve continuar sendo pesquisada interdisciplinarmente de modo a contribuir com tal participação política.
Assistentes Virtuais Inteligentes e saúde mental: debates regulatórios no Brasil
Authors: Bentes Anna , Sanches Danielle , Fonseca Paulo
Published: September 2024

A inserção dos Assistentes Virtuais Inteligentes na vida cotidiana representa um marco na história da comunicação entre humanos e máquinas. Devido às suas características interativas, estes estão sendo cada vez mais apropriados e desenvolvidos para fins de cuidado, especialmente no âmbito da saúde mental. Este artigo visa compreender se e como o debate regulatório brasileiro oferece instrumentos para lidar com os desafios e as preocupações desses sistemas de Inteligência Artificial em relação à saúde mental. A partir de uma análise documental, mapeamos exemplos de aplicação dos Assistentes Virtuais Inteligentes em saúde mental, a fim de identificar riscos a direitos dos usuários e avaliar, na legislação brasileira vigente e em discussão, se há proteção suficiente para lidar com eles. Por meio de uma abordagem crítica, salientamos a insuficiência da legislação brasileira atual e a necessidade de ampliação do debate sobre como equilibrar possíveis riscos e benefícios dessas tecnologias.
Catatonia and neurocognitive disorder in the context of schizophrenia spectrum disorders
Authors: Ignateva S. I.
Published: September 2024

Background. Currently, researchers are aiming to establish the relationship between neurocognitive disorder and other clinical manifestations of endogenous diseases and functional indicators of the patient’s adaptation to social life. According to some data, the development of cognitive disorders is associated with the severity of catatonic disorders in the clinical picture of various diseases, in particular the presence of  catatonic symptoms determines the  worst indicators of  cognitive functioning in the case of schizophrenia.

The aim. To study the clinical and psychopathological features of catatonic syndrome in connection with schizophrenia spectrum disorders, as well as its connection with neurocognitive disorder manifestations among patients with endogenous disorders.

Methods. From September 2022 to March 2024, we conducted a prospective, multicenter study of patients (n = 69) suffering from paroxysmal schizophrenia with primary catatonic symptoms in  the  structure of  attacks. Mental status, the  severity of catatonic symptoms using Bush – Francis Catatonia Rating Scale, neurocognitive profile using a number of validated scales (Montreal Cognitive Scale, Brief Assessment of Cognition in Schizophrenia, Frontal Assessment Battery) were assessed.

Results. Neurocognitive disorder was revealed in all cases studied. It has been noted that, depending on the presence/absence of affective symptoms, various domains of the neurocognitive profile are affected. Thus, in patients without severe affective symptoms, auditory and verbal memory, attention, processing speed, and motor skills are impaired. In patients with pronounced affective disorders, processing speed, motor skills, and problem-solving behavior are affected.

Conclusion. Based on  the  results of  processing the  material, it  was revealed that the most pronounced neurocognitive disorders were found in case of the manifestation of  paroxysmal paranoid schizophrenia in  male patients with a  relatively early onset of the disease and hypokinetic catatonic disorders. In the future, we are planning to compare these results with the results of control group of patients with endogenous diseases and without catatonia.
Comparative analysis of the effectiveness of laparoscopic sleeve gastrectomy and one-anastomosis gastric bypass in patients with morbid obesity and type 2 diabetes mellitus
Authors: Kolyadko P. V. , Kolyadko V. P. , Degovtsov E. N. , Satinov A. V.
Published: September 2024

Background. The effect of sleeve gastrectomy (SG) and mini-gastric bypass (MGB) are still being studied; there is a reason to believe that these methods are completely comparable in terms of achieving good bariatric results and metabolic effects.

The aim of the study. To assess the effectiveness of laparoscopic sleeve gastrectomy and one-anastomosis gastric bypass in patients with morbid obesity and type 2 diabetes mellitus by conducting a comparative analysis.

Methods. We carried out retrospective cohort study. From August 2019 to May 2023, we operated 55 patients with morbid obesity and type 2 diabetes mellitus (DM): 23 patients – in the MGB group, 32 patients – in the SG group. Median follow-up was 21 and 15 months, average age 47.6 ± 9.6 and 47.6 ± 10.7 years, body mass index (BMI) – 51.4 ± 7.8 and 50.8 ± 7.7 kg/m2, median duration of type 2 DM – 36 and 17 months, respectively. Fasting blood glucose was 7.16 ± 1.5 and 8.61 ± 2.95 mmol/l (U = 249; p = 0.022), and glycosylated hemoglobin (%HbA1c) – 6.66 ± 1.04 and 7.35 ± 1.86 % (U = 296; p = 0.222), respectively.

Results. BMI at the follow-up was 33.8 ± 6.5 kg/m2 in the MGB group and 35.5 ± 5.2 kg/m2 in the SG group (p = 0.147). Excess weight loss percentage was 68.4 ± 16.4 and 59.8 ± 14.4 (p = 0.040); total weight loss percentage – 34.1 ± 8.6 and 29.7 ± 8.0 (p = 0.109), respectively. Fasting blood glucose was 5.48 ± 1.84 and 5.39 ± 0.59 (p = 0.247), %HbA1c level – 5.3 ± 0.5 and 5.44 ± 0.58 (p = 0.230), respectively. All patients in the SG group and 22 patients in the MGB group were normoglycemic with target values of %HbA1c achieved after the surgery within a period from 3 to 12 months. There were no statistically significant differences in the number of complications (according to Clavien – Dindo II).

Conclusion. Sleeve gastrectomy and mini-gastric bypass in patients with morbid obesity and type 2 diabetes demonstrate almost similar bariatric results in the medium term. Both methods make it possible to achieve compensation for type 2 diabetes mellitus with equal efficiency within a period from 3 to 12 months after surgery.
Influence of the spread of the Beijing genotype of M. tuberculosis and its subtype B0/W148 on the incidence of tuberculosis in the population of the European and Asian Russia
Authors: Khromova P. A. , Savilov E. D. , Shugaeva S. N. , Sinkov V. V. , Zhdanova S. N. , Ogarkov O. B.
Published: September 2024

Background. For historical reasons, the incidence of tuberculosis (TB) varies significantly across geographic areas of the Russian Federation. This situation may be associated with the spread of the dominant Beijing genotype of M. tuberculosis (MBT) and of its aggressive B0/W148 subtype in the human population. Establishing a relationship between these genetic variants of MBT and the incidence of tuberculosis will serve as evidence of their epidemiological significance and a reason for decisionmaking in the TB epidemiological surveillance system.

The aim of the study. To assess the relationship between the spread of the Beijing M. tuberculosis genotype and its B0/W148 subtype with the incidence of tuberculosis in the cumulative population of the European and Asian parts of the Russian Federation.

Materials and methods. An epidemiological study was conducted, including an analysis of the distribution data of the Beijing genotype of MBT and its B0/W148 subtype (meta-analysis) in Russia and a study of TB incidence rates in the same regions. To assess the relationship, we used the Pearson’s chi-square test (χ2); the significance level when testing statistical hypotheses (p) was taken as 0.05.

Results. In the European regions of the Russian Federation, a statistically significant relationship was found between the TB incidence and the prevalence of MBT Beijing genotype (χ2 = 17.2; p = 0.009) and the absence of such a relationship with the B0/W148 subline (χ2 = 9.9; p = 0.127). In the Asian part of the Russian Federation, a highly statistically significant association was found between the incidence of TB and both the incidence of MBT Beijing genotype (χ2 = 25.4; p = 0.0001) and the incidence of its B0/W148 subtype (χ2 = 29.6; p < 0.0001).

Conclusion. A statistically significant relationship was established between the incidence of TB in the general population and the incidence of MBT Beijing genotype, regardless of the value of the average long-term TB incidence rate. In areas with high TB prevalence, a stable association was determined between the incidence rate not only with MBT of the entire Beijing family, but also with its aggressive subtype B0/W148.
Factors associated with uterine fibroids in women of reproductive age: A cross-sectional study
Authors: Babaeva N. I. , Nadeliaeva Ia. G. , Danusevich I. N. , Lazareva L. M. , Egorova I. Yu. , Atalyan A. V. , Suturina L. V.
Published: September 2024

Background. Uterine fibroids is a benign monoclonal tumor originating from the smooth muscle layer of the uterus. Non-modifiable risk factors for the development of uterine fibroids, such as age, ethnicity, age at menarche, etc, have been studied quite extensively, while the role of many controllable factors remains debatable.

The aim of the study. To identify the main modifiable factors associated with uterine fibroids in women of reproductive age living in the Baikal region, including certain ethnic groups.

Materials and methods. We carried out a multicenter cross-sectional study in 2016–2019 in institutions of Irkutsk and Bokhan (Irkutsk region) and Ulan-Ude (Republic of Buryatia). The subjects of the study were women to have annual workplace medical examination. The study included 1,347 participants of reproductive age (34.33 ± 6.37 years) who met the inclusion criteria. Among all women included in the study, there were 867 (64.37 %) Caucasians, 361 (26.80 %) Asians, and 119 (8.83%) women of mixed (Caucasian-Asian), ethnicity. The research methods included a questionnaire, general clinical and gynecological examination, and pelvic ultrasound examination.

Results. According to our study, the main non-modifiable factors associated with the presence of uterine fibroids were: Asian ethnicity; age at menarche 12–13 years; age of the study participant 40–44 years; menopausal symptoms; adenomyosis. The “controllable” factors included: city residency; body mass index over 40 kg/m2; history of abortions and miscarriages; metabolic syndrome; using combined oral contraceptives; lack of sexual activity; smoking; presence of anumber of occupational hazards.

Conclusion. Our study identified the main controllable factors associated with the presence of uterine fibroids in a multiethnic population of women of reproductive age.
Cardiopulmonary exercise test in medical and biological practice (literature review)
Authors: Kiryanov A. B. , Kozhevnikova I. S. , Farkova A. A. , Anikina N. Yu. , Yurieva E. V. , Amelina A. I.
Published: September 2024

Most tests assess physiology at rest, whereas many symptoms occur with physical exertion, and physical activity is an integral part of healthy functioning and quality of life of a person. Today, cardiopulmonary exercise testing is considered the standard for identifying exercise limitations and differentiating their causes.

Cardiopulmonary exercise testing is widely used in both basic and the latest research from cardiology and pulmonology to neurology and hematology and has great prognostic value. Cardiopulmonary exercise testing is considered the gold standard for non-invasive assessment of the cardiopulmonary system and physical performance. This study has become even more relevant and in demand due to the COVID-19 outbreak; now it plays an important role in the clinical assessment of recovering patients who have had COVID-19.

Numerous indicators recorded at each stage of the study, taken together, allow us to obtain a complete picture of the work of the cardiovascular, respiratory and muscular systems, as well as to study the characteristics of the metabolic response to stress.

This article contains a review of the literature on the history of the application and development of the cardiopulmonary exercise testing, its physiological characteristics and a study of the literature concerning application of studied method in medicine over the past 5 years. The search and analysis of articles were carried out using the scientometric databases PubMed, ScienceDirect, Google Academia.

The presented article may be useful for young specialists working in functional diagnostics, cardiology and pulmonology, as well as for researchers and postgraduates whose work involves application of the cardiopulmonary exercise testing method.
Xq12q13.2 duplication detected in a child in selective exome screening
Authors: Dokshukina A. A. , Shubina Je. , Maslennikov D. N. , Sadelov I. O. , Tolmacheva E. R. , Ionushene S. V. , Bairova T. A. , Rychkova L. V. , Trofimov D. Yu. , Degtyarev D. N.
Published: September 2024

Background. Within the framework of the regional pilot project on selective exome screening of newborn children, which is carried out on the basis of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, we conducted molecular genetic testing of children who meet the criteria for inclusion in the increased group of hereditary diseases. We examine not only children with suspected genetic etiology of the condition, but also children with borderline clinical and laboratory manifestations and minor developmental anomalies.

The aim of the study. To describe the clinical and phenotypic features of a patient with a previously undescribed Xq12q13.2 duplication detected in the neonatal period.

Materials and methods. The child was examined within the framework of a regional pilot project on selective exome screening of newborn children. DNA was isolated from a biological sample of venous blood of the newborn, and whole exome sequencing and chromosomal microarray analysis were performed. Signed informed voluntary consent for the publication of the examination data and a photograph of the child were obtained from the legal representatives of the proband.

Results. Data in favor of the presence of a previously undescribed Xq12q13.2 duplication, confirmed by the reference method were obtained in a patient included in the project in accordance with the clinical criteria for the formation of a risk group according to the data of the conducted whole exome sequencing. Discussion. Xq12q13.2 duplication was detected in the proband from the present clinical observation with non-specific clinical manifestations in the neonatal period. Similar duplications have been described in the literature in three patients with congenital malformations, epilepsy and psychomotor retardation. Early diagnosis of such a copy number variation disorder before the appearance of severe clinical signs of the disease will allow determining the prognosis and tactics of observation and treatment of the patient.

Conclusion. The described case of Xq12q13.2 duplication in a patient demonstrates the importance of timely genetic analysis to optimize medical genetic counseling, reduce diagnostic search and improve prognosis for patients.
Adherence to Recommended Care in Type-1 Diabetes Mellitus Among Adolescents and Youths Attending the Diabetes Camp in Ogun State, Nigeria
Authors: Adekoya AO , Adesina OF , Abolurin OO , Oyewole OA , Oguntade IO , Sodeinde KJ , Ale AO
Published: September 2024

Background: Adolescents and youths living with Type 1 diabetes mellitus (T1DM) are known to have challenges in managing the condition and may be prone to poor glycaemic control and complications.
Objectives: To assess the level and adequacy of care for adolescents and youths living with T1DM.
Methods: A cross-sectional, descriptive study was conducted among adolescents and youths living with T1DM who attended the 2023 Ogun Youth Diabetes Camp. An interviewer-administered questionnaire was used to obtain information. 
Results: Twenty-five participants with a mean age of 18.0±3.9 years (range 13-24 years) were recruited, with 80% being females. The mean HbA1c was 7.1 ± 1.8%, and in-camp postprandial glucose values were mostly high (76%). The mean age at diagnosis of T1DM was 11.7±4.8 years. One participant had T1DM for < 2 years, 11 for 2-5 years, and 13 for > 5 years. Among those who had lived with T1DM for more than 5 years, ten had been referred to a dietitian, nine to an ophthalmologist, and two to a neurologist. One participant had been screened for thyroid disorder.
Conclusion: The adolescents and youths living with T1DM in this survey had suboptimal glycaemic control, and evaluation by their care providers during clinic visits was also suboptimal. Therefore, they may be at increased risk of developing complications. It is recommended that all stakeholders lend timely and aggressive support to these individuals to ensure adequate management and prevent complications.
Optimizing Soil Fertility through Machine Learning: Enhancing Agricultural Productivity and Sustainability
Authors: Arısoy Ayhan , Açıkgözoğlu Enes
Published: September 2024

Nowadays, the sustainability of agriculture and food security have an increasing importance on soil fertility. Soil fertility is defined as the capacity of a land to grow crops and its potential crop productivity. However, factors such as increasing population, climate change, land use changes and environmental pollution threaten soil fertility. These threats can result in problems such as erosion, soil salinisation and organic matter depletion. Soil fertility is critical for the long-term health of agriculture and food security.

Artificial intelligence techniques used to determine and manage soil fertility analyse the minerals present in the soil as well as other factors. These analyses assess the amount of minerals present in the soil, the availability of nutrients and important parameters such as pH. This information guides farmers in selecting the most appropriate crops. Furthermore, the integration of Internet of Things (IoT) technologies allows real-time monitoring of minerals and nutrients in the soil and optimising irrigation and fertilisation processes based on this data. These developments have the potential to improve soil fertility management and increase agricultural productivity.
Study Assessment of Soil and Water Quality Conditions on Barren Agricultural Lands in Tropical Regions
Authors: Ari Handriatni  , Heri Ariadi  , Al Ramadhani Farchan Mushaf , Jazilah Syakiroh , Sajuri
Published: September 2024

Barren land is non-productive land that is difficult to use as a medium for integrated agricultural cultivation. The aim of this research is to determine the profile and feasibility status of land in barren agricultural areas quantitatively. The research method used was descriptive with purposive data collection. Data analysis included SQI and WQI parametric analyses. The research results indicate that the ideal soil parameter is only pH 7.5-7.7, while for water parameters it is pH 8.0-8.1, meeting water quality standards. SQI values range from 0.44 to 0.49 and WQI from 0.45 to 0.57. SQI and WQI values at the research site fall into the poor category, indicating difficulty in converting the land into agricultural use. SQI and WQI show a strong correlation as depicted in the model Y = 4.113 + 0.026 (R2 = 0.789). Correlation tests showed strong correlations in soil between redox potential and soil pH (0.449), and redox potential and organic matter (0.377). Weak correlations were found between cation exchange capacity and soil pH (0.009), and nitrate and total N (0.517). In water, strong correlations were found between water pH and nitrite (0.302) and ammonia (0.529). Additionally, water pH showed weak correlations with carbon dioxide (0.752) and organic matter (0.659). The values of soil and water parameters have an immediate impact on plant growth patterns. Therefore, integrated agricultural cultivation patterns need to be developed. In conclusion, empirically, the condition of barren land indicates poor land use feasibility. The poor profile and biophysical feasibility conditions of barren land are attributed to environmental pollution and runoff from other land areas.
Explorando os biomas brasileiros por meio de jogos educacionais: uma proposta para estudantes do ensino fundamental
Authors: Santos Danrvney Christian Monteiro dos , Teles Lima Mateus Vinicius , Fonseca Ferreira Thais Pereira , De Oliveira Yamazaki Regiani Magalhães , De Lima Baratela Victor Gabriel , Marques Suriano Ezequiel
Published: September 2024

O Estágio Curricular Supervisionado, indubitavelmente, é uma etapa essencial para a formação de estudantes dos cursos de licenciatura. Nesse período, os discentes, tem a oportunidade de integrar teoria à prática, construindo conhecimentos valorosos ao mediar diferentes objetos de conhecimento. Sendo assim, com o ensejo de demonstrar a importância desse momento para a formação inicial de acadêmicos dos cursos de licenciatura em Ciências Biológicas, nesse trabalho, buscou-se relatar experiências concebidas a partir de uma prática educativa sobre o tópico de ensino biomas brasileiros. Para isso, foi elaborado um plano de ensino, com o intuito de nortear as atividades teóricas e práticas idealizadas pelos professores em formação, do qual foi aplicado e analisado posteriormente, produzindo as reflexões que serão apresentadas nesse estudo. O público-alvo do desenvolvimento dessas atividades, foram estudantes do 7° ano do Ensino Fundamental de uma escola estadual da região da Grande Dourados. Após a elaboração, aplicação e avaliação das atividades, foi possível compreender a importância do Estágio Curricular Supervisionado para o preparo do exercício futuro da docência na Educação Básica. Infere-se, que atividades que fogem dos modelos tradicionais de ensino, podem contribuir significativamente na participação ativa e no protagonismo dos alunos nos processos de ensino e aprendizagem. Ademais, salienta-se sobre a importância da discussão dessa temática sob uma perspectiva crítica,  proporcionando uma maior racionalidade ambiental desses sujeitos.
Salinity Effect on CO2 Solubility in Live Formation Water Under Reservoir Conditions
Authors:   Intertek Westport Technology Center, Wang Jie ,   University of Houston, Ehlig-Economides Christine ,   University of Houston
Published: September 2024

Dissolution of CO2 in saline waters is considered one of three main CO2 trapping mechanisms, along with structural/stratigraphic trapping and mineralization. CO2 can dissolve in fresh/saline water under typical reservoir pressure and temperatures. Its solubility is dependent on pressure, temperature, and salinity. The typical assumption in open literatures regarding CO2 solubility studies—that saline water or fresh water is considered as a liquid without any pre-dissolved gases under pressures and temperatures—is not true because any formation water contains appreciable dissolved gases for all pressure and temperature conditions. An example of gas-water ratio (GWR) can be ~1 scf/stb for a saline aquifer and ~5 to 6 scf/stb for formation water in an oil reservoir. Therefore, it is essential to quantify the effect of brine salinity on CO2 solubility in live saline waters. Just as live oil is reservoir oil containing solution gas, “live” brine is defined as saline water with dissolved gases in it. Two sets of experiments were conducted under typical reservoir conditions. The first set of experiments evaluated the CO2 solubility in live formation water. The second set of experiments evaluated how variation in the live brine salinity affected CO2 solubility. These experiments involved a synthesis of the brine with three different salinities (low, medium, and high), recombination of live formation water, CO2 addition in a high-pressure and high-temperature pressure-volume-temperature (PVT) visual cell, and determination of bubblepoint pressure within the PVT cell. The results showed that CO2 solubility in live formation water is significantly less than that in “dead” water under reservoir conditions. The CO2 solubility vs. pressure curve has a much steeper slope, which indicates that CO2 can no longer be dissolved in the live brine once it reaches a certain solubility. In addition, the brine salinity affects CO2 solubility in live formation water by further reducing CO2 solubility with increasing live brine salinity. Understanding CO2 dissolution in live saline water is essential for future carbon capture and sequestration (CCS) evaluation and execution.
Acute Emotional Impact of Peer Suicide and Student-Related Factors
Authors: Lee Min Ho , Lee Han Gil , Lee Yoo Jeong , Kim Hee Jin , Seo Wan Seok
Published: September 2024

Objective This study explored the negative emotional impact of peer suicide on adolescent students during the early stages of becoming aware of suicide and examined the adverse effects of related environmental and mental health factors.Methods This study was conducted from March 1, 2020 to December 31, 2021, targeting students enrolled in middle and high schools where student suicide occurred. Emotional impact was assessed using the Korean version of the Impact of Event Scale-Revised (IES-R-K), State-Trait Anxiety Inventory-X, Center for Epidemiologic Studies-Depression Scale (CES-D), and Beck’s Scale for Suicide Ideation (SSI). χ2 test and Pearson’s correlation analysis were performed to analyze subgroup differences and explore relationships between scale scores, respectively.Results Of the 2,382 participants, 25.1% belonged to the post-traumatic stress disorder (PTSD) or PTSD tendency group on the IES-R-K, and 22.2% showed abnormalities in the State-Trait Anxiety Inventory-State. Students in the same class as the deceased student and those in the same grade but in different classes had higher risk rates than those in different grades. Boarding school students had 1.9 times higher odds of experiencing emotional impacts than non-boarding students. On the CES-D, 10.4% of the students showed potential depression, with 3.7 times higher odds of experiencing emotional impact than those with normal scores. Moreover, 4.5% of the students reported suicidal ideation on the SSI, with those experiencing mild suicidal ideation having 1.9 times higher odds of experiencing emotional impact than those with normal scores.Conclusion A significant proportion of students experienced negative impacts of peer suicide. Students in close-knit environments, such as the same class, grade, and boarding school as the deceased, or those with depression or anxiety experienced a more pronounced negative impact.
Dynamics of Stock Prices and Exchange Rate with Structural Breaks and Asymmetry: Evidence From Türkiye
Authors: Burgaç Çil Almıla , Biçer Burhan
Published: September 2024

This study investigates the impacts of the nominal exchange rate on Turkish stock prices using a structural break cointegration test with endogenously determined multiple structural breaks and an asymmetric cointegration test for the period of 2002-2021. The study differs from previous research on this relation in two respects. First, it takes into account structural breaks in relation to both regimes and trends (C/S/T). Second, it extends the asymmetric cointegration with multiple structural breaks. The findings of structural break cointegration capture the break dates in line with the Turkish economics dynamics and reveal the negative effects of the exchange rates on stocks, with their significance and magnitude differing in regimes. Similarly, NARDL results indicate that negative and positive exchange rate shocks exhibit asymmetric effects on stocks for both the whole period and regimes. The overall findings demonstrate that exchange rate variations have distinctive impacts on stock prices when considering structural break and asymmetrical dynamics. In this background, policymakers and foreign investors need to take into account these dynamics when dealing with Turkish financial markets.