bluuebunny/crossref_metadata_2025 huggingface dataset:
Análisis del Programa de Tutoría como Proceso Fundamental en su Formación en el área de Ingeniería del ITS Mante
Authors: Rangel Anguiano Roberto , Avalos Robles Adriana , Sobrevilla Pintor Verónica , Laurence Santillan Maria del Carmen , Rojas Rivera Concepción del Carmen
Published: December 2024

En la presente investigación se aborda la tutoría como el proceso de acompañamiento de los estudiantes a lo largo de su tránsito escolar en una Institución. Se presentan los antecedentes y la situación actual del Programa Institucional de Tutorías en el Instituto Tecnológico Superior de El Mante perteneciente al Sistema del Tecnológico Nacional de México, así como algunos indicadores clave que se analizan para elevar el rendimiento académico y evitar la deserción escolar. Además, el objetivo que se establece es analizar la apreciación de los estudiantes del Instituto Tecnológico Superior de El Mante sobre las estrategias y desempeño de sus tutores, con la finalidad de identificar fortalezas y puntos de mejora para elevar la calidad de servicio en el proceso de tutoría. La investigación es de corte cualitativa-descriptiva, la cual se centra en analizar las cualidades del proceso de formación integral y se han logrado identificar los indicadores que resultan más significativos en dicho proceso y con esto se ha planteado una resolución como propuesta para fortalecer el programa a través de una jornada de capacitación y establecer los periodos de evaluación para impulsar en mayor medida la tutoría en la educación superior, y mejorar el proceso.
UPAYA GURU DALAM MENGATASI KENAKALAN SISWA MADRASAH IBTIDAIYAH
Authors: Tamjidillah HM Amin
Published: December 2024

Penelitian ini merupakan penelitian deskriftif yang bertujuan untuk menggali informasi tentang bentuk, faktor dan upaya guru dalam mengatasi kenakalan remaja di Madrasah Ibtidaiyah. Pemerolehan informasi melalui observasi, wawancara dan dokumentasi yang dianalisis melalui tahapan reduksi, penyajian data dan penarikan kesimpulan. Hasil penelitian menggambarkan bahwa bentuk kenakalan remaja diwujudkan melalui aktivitas bertengkar, berpakaian tidak rapi, berkata kotor dan malas. Adapun faktor kenakalan remaja dipengaruhi oleh faktor eksternal dan internal. Bentuk dan kenakalan remaja tersebut dapat diatasi dengan pretensi pencegahan, refresif, dan kuratif.
Pemahaman dan Persepsi Generasi Muslim Milenial terhadap Produk Investasi Syariah
Authors: Meldi  , Denisa Sundari  , Dina Egi Marsamelia  , Viona Agustin Hidayani  , Refskin Takari
Published: December 2024

ABSTRACT
The interplay between religion and finance in investment practices witnessed by Indonesia in 2019 reflects an important shift in the country's economic landscape. The purpose of writing this journal is to reveal the ins and outs of consumer behavior dynamics in the context of Islamic finance based on understanding and perception. The method used is descriptive qualitative with reference to secondary data in the form of literature. The results found that the millennial generation's understanding and perception of Islamic investment products are strongly influenced by educational factors, religious influences, as well as the experience and information they get.
 
ABSTRAK
Keterkaitan antara agama dan keuangan dalam praktik investasi yang disaksikan oleh Indonesia pada tahun 2019 mencerminkan perubahan penting dalam lanskap ekonomi negara ini. Tujuan penulisan jurnal ini adalah untuk mengungkap seluk beluk dinamika perilaku konsumen dalam konteks keuangan syariah berdasarkan pemahaman dan persepsi. Metode yang digunakan adalah deskriptif kualitatif dengan mengacu pada data sekunder berupa literatur. Hasil penelitian menemukan bahwa pemahaman dan persepsi generasi milenial terhadap produk investasi syariah sangat dipengaruhi oleh faktor edukasi, pengaruh agama, serta pengalaman dan informasi yang mereka peroleh.
Molecular Mechanisms of Chronic Stress in Immune Dysregulation: From Cytokine Networks to Clinical Manifestations
Authors:   Data Scientist, Montgomery Richard Murdoch
Published: December 2024

This article examines the intricate molecular mechanisms linking chronic stress to immune system dysregulation, with particular emphasis on cytokine networks and their role in disease development. Recent advances in molecular immunology have revealed sophisticated pathways through which persistent stress influences immune function, leading to various pathological conditions. We analyze the complex interactions between neuroendocrine responses and immune regulation, focusing on how stress-induced alterations in cytokine networks affect both innate and adaptive immunity. The article integrates findings from research in extracellular vesicle signaling, metabolic reprogramming, and epigenetic modifications in immune cells under chronic stress conditions. Special attention is given to the tissue-specific immune responses and the role of the gut-brain axis in mediating stress-induced immune alterations. We discuss how these molecular mechanisms contribute to the development of immunodeficiency, autoimmune conditions, and chronic inflammatory states. The review also explores emerging therapeutic strategies based on these molecular insights, including chronoimmunotherapy and targeted cytokine modulation. Understanding these complex interactions provides crucial insights for developing more effective treatments for stress-related immune disorders.
Thinking Reflectively: Insights from Academic Leaders in Higher Education
Authors: Arshad Mahek , Naz Tabassum
Published: December 2024

Reflective thinking is essential for effective leadership in higher education, enabling academic leaders to address complex challenges and improve decision-making and problem-solving skills. This study explores the importance of reflective thinking for academic leaders, focusing on its role in fostering open-mindedness, critical evaluation, and continuous learning. The study adopted a mixed-method approach, with semi-structured interviews with 13 department heads and a survey of 130 academic administrators across universities in Islamabad. The findings of the study highlight the necessity of reflective thinking for strategic decision-making, conflict resolution, and the creation of a positive institutional culture. Reflective thinking encourages academic leaders to consider multiple perspectives, identify patterns, and challenge assumptions, thereby facilitating innovative solutions and adaptive strategies. Key elements identified include open-mindedness, full engagement, and accountability, which are essential for effective reflection. By addressing these challenges, the study proposes practical strategies for fostering reflective thinking skills, including participation in communication networks and continuous professional development. Overall, this study contributes to the field of higher education leadership by providing insights into the role of reflective thinking in improving decision-making and problem-solving. It advocates for the integration of reflective practices into leadership development programs and emphasizes the importance of fostering a culture of reflection to improve the overall effectiveness of academic institutions. Through continuous self-reflection and adaptive leadership, academic leaders can better navigate the complexity of their roles, ultimately benefiting faculty, staff, and students. Quantitative analysis revealed that 85% of the surveyed academic administrators identified reflective thinking as crucial in their leadership roles.
Obstacles to Sustainable Development in Higher Education Institutions of Pakistan
Authors: Shaheen Ajaz , Khakwani Sofia , Tabassum Rabia
Published: December 2024

This research paper explores the obstacles to sustainable development in Pakistan's higher education institutions (HEIs), focusing on challenges in implementing sustainability initiatives within academic and administrative settings. Despite the global emphasis on sustainability, Pakistani HEIs face several barriers that hinder the integration of sustainable development into curricula, research, and campus operations—the research problem centers around understanding these challenges and their impact on promoting sustainability in higher education. The study aims to identify the key obstacles preventing the effective implementation of sustainable development initiatives in Pakistani HEIs. Theoretical frameworks on sustainable development in education and institutional change guide the research. Phenomenology is a type of qualitative research involving semi-structured interviews with lecturers, professors, and educational administrators from various HEIs across Pakistan. Data is analyzed using thematic analysis to uncover recurring themes related to sustainability challenges. Results of the study revealed that insufficient policy support, inadequate funding, a lack of faculty training, and limited student engagement are significant obstacles to sustainability in HEIs. Additionally, participants emphasized the need for better institutional strategies and more robust government policies. The study underscores the urgent need for policy reforms, capacity-building initiatives, and increased financial support to promote sustainable development in Pakistani HEIs. Recommendations include improving policy alignment with global sustainability goals, fostering public-private partnerships, and integrating sustainability into academic curricula and research practices.
Renewable Energy, Financial Growth and Technological Progress: Analyzing the Dynamics of Sectoral Emissions in Pakistan
Authors: Khalil Luqman , Azhar Khan Muhammad , Zaman Khalid
Published: December 2024

The study examined the role of renewable energy, financial growth, and technical progress in Pakistan's industrial, manufacturing, and service sector emissions. The study collected consistent time series data from 1975 to 2022 and employed the ARDL-Bounds testing approach to estimate the short- and long-term parameter estimates. The study assessed three broad models. The first model linked renewable energy to carbon emissions in the cement industry. Carbon emissions and renewable energy were negatively related. Further, a negative relationship exists between information and communication technologies (ICTs) and carbon emissions, with a one-unit increase in ICT reducing CO2 emissions by 0.135 units. A substantial and positive association was found between GDP per capita and CO2 emissions in Pakistan. At the same time, the square term decreases carbon emissions, supporting a country's environmental Kuznets curve (EKC) hypothesis. In the second model, high technology exports were positively connected with manufacturing CO2 emissions, while energy use's interaction term had a significant negative impact. Manufacturing CO2 emissions were positively correlated with renewable energy in the short and medium term. Financial development is assessed by money supply, which directly affects carbon emissions to support financial-led emissions in a country. The third model used GHG emissions as the dependent variable and focused on the service sector. The interaction term between energy consumption and clean fuel technology (CFT) was negative and significant, although GHG emissions and CFT were positively correlated. Non-renewable energy raised GHG emissions, while renewable energy decreased them.
From terminological inconsistencies to major mistranslations
Authors: Šorak Vanessa
Published: December 2024

This article presents a qualitative analysis of frequent NMT errors in public health communication. Its primary aim is to sensitise users and decision-makers to common issues and raise public awareness for potential pitfalls and limits of current state-of-the-art NMT systems. In this context, the article also addresses the usability of raw NMT output in emergency situations. The investigation itself focuses on pandemic-related WHO texts and consists of a fine-grained manual error analysis encompassing three languages (English, French, and Spanish) and two NMT systems (DeepL and Google Translate). The five most frequent error types observed in this investigation included mistranslations, inconsistent use of terminology, unidiomatic or awkward style, untranslated text, and other internal inconsistencies. These error types are illustrated with examples and analysed in terms of their severity, their underlying causes, and their potential consequences. The findings show that raw NMT output is useful only to a very limited extent and that the risks and benefits associated with its use should be assessed extremely carefully.
Review of The Performance, Emission, And Challenges Faced by Hydrogen-Powered Internal Combustion Engines
Authors: Thejaraju R  , Gowtham Sanjai S  , Hadiya Pritesh Dulabhai  , Sajna S Panigrahi
Published: December 2024

Hydrogen-powered internal combustion engines (ICEs) provide an encouraging proposal to reduce vehicular emissions and improve energy efficiency. These engines are characterized by enhanced thermal efficiency and lower emissions of CO2 and NOx compared to traditional fossil fuel-powered engines, aligning them with stringent global environmental regulations. However, the broader adoption of hydrogen ICEs is hindered by several challenges. Key areas among these are the advancement of effective hydrogen storage solutions and fuel delivery systems, along with the establishment of a robust infrastructure for hydrogen production and distribution. Additionally, technical challenges such as the risk of pre-ignition, backfiring, and maintaining consistent performance under variable engine loads present significant obstacles. Overcoming these challenges is essential for successfully integrating hydrogen ICEs into the automotive sector. Addressing these issues will enable the pervasive use of hydrogen as a sustainable vehicle fuel and significantly reduce the automotive industry’s environmental footprint.
Customer satisfaction status. Strategies and ways to address it
Authors: Maldonado Emanuel Jose
Published: December 2024

Introduction: customers focus on obtaining services or products where they are treated with cordiality, friendliness and courtesy; in order to establish a degree of empathy with the service provided. Objective: assess the state of customer satisfaction based on their approach to strategies and ways of addressing it.Method: a research review of the scientific literature was developed. Descriptors were used to search for information. The search was carried out in the Scielo and SCOPUS databases. A total of 20 works were used for the development of the research.  Development: the international business system faces a globalized economic system, where competition through the free market is based on the quality and effectiveness of the products offered. Feedback with customers is an important indicator that determines the level of productivity of a sector; In other words, we talk about the degree of customer satisfaction.Conclusions: customer satisfaction should be considered one of the main goals within business objectives. Depending on the degree of satisfaction, the wealth that a company in question can produce is determined. Its approach must be comprehensive, based on new tools (mostly digital) that help to understand it in real time. In turn, work strategies and/or work environment are updated and perfected in order to achieve better conditions that translate into greater satisfaction on the part of the consumer or client
A droplet digital PCR assay for the detection of Fusarium oxysporum f. sp. cubense Tropical Race 4
Authors: Lovera Andrea , Rodríguez Edwin , Simbaqueba Jaime , Burbano-David Diana , Carmona Sandra L. , Izquierdo-García Luisa F. , Gómez-Correa Juan C. , Leon-Pacheco Rommel I. , Parra-Fuentes Madeleyne , Rodríguez Gustavo , Betancourt Mónica , Zuluaga Paola , Soto-Suárez Mauricio
Published: December 2024

Fusarium wilt of banana, caused by the pathogen Fusarium oxysporum f. sp. cubense Tropical Race 4 (Foc TR4) is a threat for food security as it affects global banana industry. The development of early detection strategies of Foc TR4, from asymptomatic tissues with low inoculum concentration and environmental samples is an indispensable prerequisite to restrict the pathogen spread and minimize the environmental impact by eradicating an area with accurate data of the pathogen’s presence. In this study, three different PCR technologies (conventional PCR, qPCR and ddPCR) were evaluated for Foc TR4 detection in complex environmental samples. We report the development of a sensitive and specific ddPCR primer/probe set and protocols that can be used as a tool for Foc TR4 detection from plant tissue without prior DNA extraction, symptomatic and asymptomatic plant tissue, drainage waters, footbaths and soil samples.
Biomimetic research on posture optimization of sprinters: Inspiration from high-speed moving organisms in nature
Authors: Zhang Jing
Published: December 2024

Biomechanics of sprinters’ posture is critical to maximizing speed and efficiency. Inspired by high-speed organisms in nature, such as cheetahs and falcons, this research examines biomimetic principles to optimize sprinters’ running posture. High-speed animals possess unique anatomical and mechanical traits, allowing remarkable acceleration, stability, and energy efficiency. These characteristics provide valuable insights into improving human sprinting performance. The investigation begins with an in-depth analysis of these organisms’ musculoskeletal systems and movement patterns, focusing on their body alignment, limb positioning, and force application during high-speed locomotion. This data is the foundation for developing biomechanical models applicable to human sprinters. The models are further validated through motion capture technology and simulations, where adjustments to sprinters’ postures are tested for speed, stride length, and energy efficiency improvements. Results from the experiments show a significant reduction in energy wastage and increased propulsion when sprinters adopt optimized postures inspired by natural high-speed organisms. Key adaptations include adjustments in trunk alignment, arm movement coordination, and lower limb force generation, closely mirroring the dynamic posture control seen in nature. This research demonstrates that adopting biomimetic insights leads to measurable sprinting efficiency and performance enhancements. The findings also contribute to developing training protocols for athletes, focusing on optimizing posture based on natural biomechanics.
Optimization of rigid endoscope drying method based on negative pressure suction device: Evaluation of its impact on drying efficiency and occupational safety
Authors: Zhang Lian , Zeng Xiuyue , Zheng Haoling , Tan Zhishan , Deng Lihong , Chen Hongchang
Published: December 2024

Methods: A randomized controlled trial design was employed. Four types of rigid endoscopes were selected: fiber optic instruments, lens instruments, forceps instruments, and tubular instruments, with 100 samples from each category. The samples were assigned to a control group (traditional drying method) and an experimental group (negative pressure suction device). The experimental group used a negative pressure suction device combined with a drying cabinet for drying, while the control group employed wiping, a high-pressure air gun, and a drying cabinet. Drying time for each type of instrument was measured, and noise levels during the drying process were assessed using a noise meter. The data were analyzed using independent sample t-tests for intergroup comparisons, with a significance level set at P < 0.05. Results: The experimental group showed significantly shorter drying times for fiber optic instruments, lens instruments, and forceps instruments compared to the control group. The drying time for fiber optic instruments in the experimental group was 316.9 ± 1.97 s, significantly shorter than the control group’s 326.53 ± 4.43 s (t = 6.28, P < 0.001). The drying time for lens instruments in the experimental group was 315.07 ± 1.80 s, compared to 320.54 ± 4.21 s in the control group (t = 3.78, P < 0.001). However, for tubular instruments, the experimental group’s drying time was 660 s, markedly longer than the control group’s 327.04 ± 4.99 s (t = 211.09, P < 0.001). In terms of noise levels, the experimental group exhibited significantly lower noise exposure for fiber optic and lens instruments compared to the control group. The average noise for fiber optic instruments was 45.79 ± 0.17 dB in the experimental group, while it was 63.73 ± 0.67 dB in the control group (t = 82.55, P < 0.001). Conclusion: The negative pressure suction device significantly improves the drying efficiency of rigid endoscopes, especially for instruments with simpler structures, and effectively reduces noise exposure, enhancing occupational safety. However, for complex tubular instruments, further optimization of the negative pressure suction device is required.
Protecting the Right to Own Land Through the Prism of Resolving Land Disputes
Authors: Belikova, Mishchuk Svitlana, Mykola
Published: December 2024

According to the provisions of Articles 13 and 14 of the Constitution of Ukraine, land is an object of the right of ownership of the Ukrainian people and the main source of national wealth, and is under the special protection of the state.
Thus, Article 13 of the Constitution of Ukraine provides that the state ensures the protection of the rights of all subjects with regard to the right of ownership and management. It also establishes equality before the law of all subjects of property rights without exception and guarantees everyone the protection of their rights and freedoms. These fundamental provisions of the Basic Law of Ukraine are of decisive importance for the subjects of land relations.
Consequently, the Land Code of Ukraine guarantees and provides individuals and legal entities with equal conditions and ways to protect the right of ownership and the right to use land. The owner of a land plot or a land user may demand the elimination of any violations of his land rights, even if these violations are not related to the deprivation of the right to possess or use (on a lease basis) a land plot, as well as compensation for the damage caused.
This Code provides that all lands within its territory, including islands and lands occupied by water bodies, belong to the lands of Ukraine.
Part 1 of Article 78 of the Land Code of Ukraine discloses the content of the right to own land – this is the right to own, use and dispose of land plots. As a result of disagreements arising in the application of legislation or disputes arising in the event of a violation of this right (the ownership, use and disposal of land plots), such disputes are resolved in an administrative and judicial manner.
The article argues for the protection of the property rights of individuals and legal entities to a land plot. Such protection is especially relevant when resolving land disputes arising from violations of the right to own, use and dispose of land plots. To this end, the article has four sections, which, together with examples from judicial practice, reveal the essence of protecting land rights. These are the following sections:
1. Protection of land rights, carried out in an administrative and judicial manner;
2. Responsibility for the violation of land legislation;
3. Substantive jurisdiction of the resolution of land disputes by a court;
4. Judicial control over the execution of a court decision on land disputes.
Thus, the article sets out the protection of land ownership through the prism of resolving land disputes.

Słowa kluczowe: protection of land rights, land ownership, right to use a land plot, right to dispose of a land plot, civil liability, administrative liability, criminal liability, land disputes, land plot, subject matter jurisdiction, civil jurisdiction, administrative jurisdiction, economic jurisdiction, judicial control
Oczywista niecelowość wszczęcia postępowania egzekucyjnego w przypadku zgonu dłużnika przed wszczęciem tego postępowania
Authors: Dziewulska Monika
Published: December 2024

Obvious Aimlessness of Initiating Enforcement Proceedings in Case of Debtor’s Death before Initiating the Proceedings
For years, numerous interpretation difficulties have been caused, albeit unjustifiably, by the matter of charging a creditor with an enforcement fee in case of an obviously aimless initiation of enforcement proceedings, due to the death of a debtor before initiating such proceedings. In view, among other, of the consistency of the legal system and taking into account regulations included in the Code of Civil Proceedings with regard to the obvious unfounded lawsuit or actions that are obviously aimless as well as regulations concerning court enforcement proceedings included in the Act of 22 March 2018 on bailiffs and the Act of 28 February 2018 on bailiff costs, the determination and collection of such fees, as a duty of a bailiff, has always had a normative basis and been justified. Any doubts in this respect have been cleared by the Supreme Court, which in its Resolution of 27 January 2022 indicated that filing an enforcement application by a creditor against a deceased debtor constitutes an obviously aimless initiation of enforcement proceedings in the meaning of art. 30 of the Act of 28 February 2018 on bailiff costs.

Keywords: court capacity of parties in enforcement proceedings, obvious aimlessness of initiating enforcement proceedings, enforcement fee
Przysądzenie własności nieruchomości po uprawomocnieniu się postanowienia o ogłoszeniu upadłości dłużnika. Glosa do uchwały Sądu Najwyższego z dnia 18 listopada 2021 roku (III CZP 77/20)
Authors: Cieślak Sławomir
Published: December 2024

On the basis of the current legal status, it should to be accepted the Supreme Court’s view that the binding decision of declaring the debtor’s bankruptcy is not an obstacle to award the ownership of real estate to an auction purchaser who has been legally confirmed before the non-binding decision of declaring the debtor’s bankruptcy and who has fulfilled the auction conditions (Article 998 § 1 KPC). Despite the failure to observe the minimum limit of procedural formalism in this interpretation, de lege lata the application of the solution to the procedural problem proposed by the Supreme Court in the commented resolution is necessary and meets the needs of the practice of civil proceedings.
The optimal solution to the above-mentioned problem of the lack of sufficient protection of the auction purchaser’s rights should be amended by the Legislator, because the binding regulation may reduce the interest of potential bidders to participate in public auctions in judicial enforcement proceedings. It would consist in introducing in art. 146 paragraph 1 of the Polish Bankruptcy Law, the institution of the discontinuance of the enforcement proceedings ex officio by the enforcement authority, instead of the discontinuance ex lege.

Keywords: adjudication of ownership of real estate, confirmation of enforcement against real estate, declaration of bankruptcy, auction purchaser, discontinuance of the enforcement proceedings ex lege, discontinuance of the enforcement proceedings ex officio
Quercetin Regulates the Polarization of Microglia through the NRF2/HO1 Pathway and Mitigates Alzheimer's Disease
Authors: Feng Ying , Yu Xinjun , Han Jingyang
Published: December 2024

Background: Alzheimer's disease (AD) is a burdening disease and is the main cause of dementia. Quercetin (Que), an antioxidant, plays potential roles in treating age-related disorders, including AD. This study aimed to validate the effects of Que on AD and explore the underlying mechanisms. 
Methods: Mice with no treatment, amyloid-β Aβ (1-42) treatment (for acquiring AD model), or Aβ (1-42) plus Que treatment were used. Cognitive function was determined using the open field test (OFT), objective recognition test, and Y-maze test. In brain tissues, mRNA levels of inflammation cytokines, the M1 microglia marker cluster of differentiation (CD)86, and the M2 microglia markers arginase 1 (Arg1) and CD206 were measured. Nuclear factor E2-related factor 2 (NRF2)/heme oxygenase-1 (HO1) pathway-related proteins were detected by western blot. Additionally, mechanisms were investigated using human microglia HMC3 cells treated with Aβ (1-42) and Aβ (1-42) plus Que. The NRF2/HO1 pathway in HMC3 cells was inhibited using the selective inhibitor ML385. Cell viability and death were assessed using the cell counting kit-8 (CCK-8) and lactate dehydrogenase (LDH) release levels, respectively. Cell apoptosis was measured by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL). Levels of NRF2/HO1 pathway-related proteins, inflammation cytokines, and oxidative stress-related markers, including malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione (reduced glutathione (GSH)/oxidized glutathione disulfide (GSSG)), were determined in HMC3 cells. Flow cytometry was used to determine M1 markers CD86 and CD80 and M2 markers CD206 and CD163. 
Results: Cognitive ability was impaired in AD model mice, and Que treatment reversed this impairment (p < 0.05). Levels of interleukin (IL)-1β, tumor necrosis factor-alpha (TNF-α), and IL-6 were increased, while M2 markers were decreased in the AD model mouse brain. Que treatment reversed these changes (p < 0.001). The NRF2/HO1 pathway was slightly inhibited in AD mice brain, while further activated by Que (p < 0.05). Que reversed the Aβ (1-42)-impaired cell viability. Through greatly activating NRF2/HO1 pathway, Que suppressed Aβ (1-42)-induced cell death, decreased Aβ (1-42)-promoted IL-1β, TNF-α, IL-6, MDA, CD86 and CD80, increased Aβ (1-42)-suppressed SOD and GSH/GSSG, and greatly increased CD206 and CD163 (p < 0.01). 
Conclusion: Quercetin, through the activation of the NRF2/HO1 pathway, promotes M2 polarization of microglia, suppresses Aβ (1-42)-induced inflammation and oxidative stress, protects microglia from Aβ (1-42)-induced damage, improves cognitive function in mice, and demonstrates therapeutic potential for AD.
Inclusion of Digital Citizenship Skills in the Modified Educational Syllabi at Ha’il University: A Study in Teachers’ Perspective
Authors: Alotaibi Wadha Shabib Ali
Published: December 2024

In the wake of Covid-19 pandemic and the educational scenario shifting towards online teaching, universities brought about several modifications in their courses to accommodate online dissemination. These changes inspired learners and teachers to acquire the traits of digital citizenship (DC) skills. The present study investigates the perspectives of teaching staff at Ha’il University, Saudi Arabia, on the degree of inclusion of digital citizenship skills in the modified educational syllabi. In a mixed methods study, teachers' perspectives on the topic were collected from 227 participants. The data were collected through a survey questionnaire and statistically analysed using SPSS. To check the differences across variables, the following variables were used: academic degree, professional experience, and academic track. The obtained results showed that the teaching staff displayed a medium degree of satisfaction with the inclusion of DC skills in the educational syllabi. No significant differences between the means of responses of the study sample were observed (p> 0.05). The study findings have implications for instructors and learners. The researchers recommend further research in the area, and it is essential that training courses are conducted to increase the awareness of DC skills to develop digital content and to maximize the use of ICT tools especially in the light of the covid-19.
The Impact of Game-Based Learning on Computational Thinking and Language Learning Attitudes in Higher Education Students
Authors: Al Mahrouqi Raya Saleem , Khodabandelou Rouhollah , Osman Mohamed Eltahir
Published: December 2024

Computational thinking (CT) is recognized as a fundamental skill in the 21st century, potentially improving problem-solving and creative thinking abilities. Given its broad applicability, there is a growing emphasis on introducing CT in education. Additionally, Oman Vision 2040 underscores the importance of advancing education and nurturing a highly skilled workforce, emphasizing the need for computational thinking, problem-solving, critical thinking, and algorithmic reasoning skills. Thus, since previous research has primarily focused on middle and high school students, and the studies for higher education showed that students lack CT competencies, this study extends the investigation to higher education students. Moreover, integrating CT into the curriculum calls for innovative teaching methods, such as game-based learning, which promises to engage students in complex activities closely aligned with CT principles. This research endeavors to investigate the impact of game-based learning on the CT skills and attitudes towards language learning of higher education students with consideration of potential gender-based differences. The problem statement highlights CT's significance and the pressing need for improved CT competencies among students. A comprehensive methodology employed a quasi-experimental design, encompassing pre-and post-tests, interviews, and questionnaires, to gather data from 24 Sultan Qaboos University Foundation students. The findings showed a considerable positive impact on students’ CT skills as well as their language learning attitudes. In light of the research findings, it is recommended that game-based learning be incorporated into higher education curricula to enhance CT skills and engagement.
Comprehensive Review of the Role of Medical Secretaries in Health Administration and Modern Healthcare Systems Management
Authors: Makrash Majed Ahmed , Jarh Naseem Alhassan Ali , Hakami Maryam Mohammed A , Almodeer Abdulrhman Mohammed , Daeya Ibrahim Ahmed , Bejh Moath Adil Ali , Jafari Lara Hussin Jaman , Qami Waleed Mohammed A , Hawthan Khaled Hassan H , Alsharari Ahmed Awdah A , Almuammar Hussain Musalli M
Published: December 2024

Medical secretaries, also known as medical office assistants or healthcare administrators, ensure that healthcare organizations and the broader healthcare delivery systems are run daily. Explores the broad growing utility of medical secretaries in clinical organizations, specifically concerning patient treatment and clinical operation in healthcare organizations, more so about the applicability of information technology in healthcare facilities. In this context, the literature review intends to overview their duties and responsibilities, training, issues they face, and contributions to efficient healthcare delivery, patient satisfaction, and organizational outcomes. We can reaffirm the essentiality of medical secretaries in today's healthcare organizations and recommend measures for improving their position based on education, implementing new technologies, and professional training.
Comprehensive Exploration of Biomedical Science in Transforming Global Health
Authors: Alsallum Shakhis Daws D , Banihumayyim Hadi Ali H , Alsallum Mohammed Hussain M , Lasloum Ahmad Hadi A , Alsallum Salem Hussain M , Humayyim Abdullah Khalid A , Humayyim Abdullah Khalid A , Algashaneen Mana Abdullah A , Lsallum Abdullah Saad M , Alsallum Hamdan Hussain D , Lasloum Ali Ahmad M , Alyami Alyan Mohamad M
Published: December 2024

Biomedical science has supervised tremendous changes in what the world considers health and how diseases are prevented, diagnosed, and treated. From the discovery of vaccines and diagnostic aids to innovations in genetics and genomic personalized medicine, spot the discipline as a key determinant of advancing the delivery and models of health Systems globally. This paper aims to review the effect of biomedical science on global health with a focus on retrospect and prospects of diseases, health, and crises. Thus, relying on up-to-date research, cases, and world health studies, the work reveals successes and failures. As for recommendations, they are to encourage innovation, extend the usage of biomedical technologies and involve individuals and disciplines expecting to make a positive change in the coming years that is stable and effective.Biomedical Science
Rhetorical Miracles in the Vocabulary of Quranic Composition Surah Al-Ikhlas as a Model
Authors: Alsaied Mohamad Abdullah
Published: December 2024

This research aims to uncover the facets of rhetorical miracles in the vocabulary of one of the chapters of the Holy Quran, specifically Surah (Al-Ikhlas). This surah is among the shorter chapters that encapsulate matters of faith and numerous benefits through magnificent and high-level rhetorical forms. This is because the Holy Quran, which is concise and succinct in its words, verses, and chapters, possesses all aspects of eloquence in their various forms comprehensively and entirely ranging from clarity and literary beauty to profound meanings all interconnected without any fragmentation or flaw. This invites us to observe these facets in the vocabulary of this noble Quranic surah, highlighting its high status and elevated position similar to other great chapters of the Quran and its profound sanctity. This is because it is the miraculous word of God in its expression and clarity, and its noble meanings. All of this falls under a type of thematic interpretation in its rhetorical form, presented in a concise manner, carrying many subtle details of Quranic meanings, hinted at through the composition of words and the structure of terms, in an eloquent manner found only in the Great Quran.
Beyond the Binary: Investigating the Differential Effects of Microcredit on Poor and Near-Poor Households
Authors: NGUYEN Quynh Hoa, , NGO Quoc Dung, , HOANG Vu Hiep,
Published: December 2024

This study employs difference-in-differences methodology to examine the impact of formal microcredit on income levels of poor and near-poor households in Vietnam using panel data from 2016-2018. Findings reveal microcredit participation leads to a 0.021% increase in average income over time, with loan size, purpose, and household characteristics significantly influencing outcomes. The research contributes a nuanced analysis of microcredit's differential effects across income groups, incorporating credit use as a key variable. Results have implications for designing targeted interventions maximizing microcredit's poverty alleviation potential. Policymakers should promote productive credit use and support services tailored to borrowers' needs.
A Study on the Relationship between Family Shareholding and Company’s Operating Performance - Evidences from a Small Open Economy
Authors: Li Jian-Fa , Chang Ni-Chen , Li Katherine A.
Published: December 2024

Our study is to investigate how the ownership structure and financial aspects of family-controlled firms influence their operating performance. The interests of major shareholders are aligned, this could positively impact the company's operating performance. Conversely, dominant shareholders might entrench themselves in a way that doesn't necessarily benefit the operating performance. The presence of a second largest shareholder acts as a check and balance on the first largest shareholder. We reveal an inverted U-shaped relationship between the shareholding ratio of foreign institutional investors (SRFII) and operating performance. It suggests that as SRFII increases, operating performance initially improves but might decline after reaching a certain threshold. This finding highlights the importance of maintaining balance in SRFII to ensure alignment of interests between company leadership and the company's overall goals. Excessive foreign ownership could potentially lead to divergent interests that may not be aligned with the company's best interests. We also find that higher equity pledge ratio among key leadership roles might adversely affect operating performance. Pledged shares could restrict decision-making flexibility and potentially lead to conflicts of interest. These findings shed light on the complex dynamics within family-controlled firms, particularly how ownership structure and financial arrangements could influence operational outcomes.
Увеличение срока использования минерализованных буровых растворов
Authors: А.Ю. КУРЕННЫХ , Е.В. СЕРАЯ
Published: December 2024

При бурении скважин на месторождениях ПАО «Сургутнефтегаз» возникают осложнения, связанные с ухудшением технологических свойств промывочной жидкости при повторном применении бурового раствора на основе природных полимеров. В целях ликвидации осложнений предлагается рассмотреть компонентный состав бурового раствора – хлоркалиевый буровой раствор по рецептуре № 9 и 9.1. В данной статье рассмотрены три предлагаемых технологических решения, которые имеют научно-практическую значимость и рекомендованы к проведению опытно-промышленных работ.

When drilling wells at the fields of PJSC Surgutneftegas, complications arise associated with the deterioration of the technological properties of the drilling fluid when reusing drilling mud based on natural polymers. In order to eliminate complications, it is proposed to consider the component composition of the drilling mud – potassium chloride drilling mud according to recipe No. 9 and 9.1. This article examines three proposed technological solutions that have scientific and practical significance and are recommended for pilot industrial work.
Measuring the Impact of Job Characteristics on Job Crafting: The Mediating Role of Employee Readiness and the Moderating Effect of Social Support
Authors: Mohsin Muhammad , Aid Adeel , Aslam Maryam
Published: December 2024

Employees implement alterations to their work responsibilities, termed "job crafting." Based on this phenomenon, this research assesses the impact of skill diversity, a component of work characteristics, on employee job crafting. It examines the influence of employee readiness and external resources, such as job security, autonomy, and feedback, on job design. The research aims to understand the interaction and influence of these factors on workers' job-crafting behaviors. The present study investigated the relationships among several aspects within the IT sector. A random sample of 350 workers was collected using an online questionnaire for data analysis utilizing probability sampling. Data analysis has been conducted using SPSS 26 and Smart PLS 3.0. This research enhances our comprehension of employee work customization by illustrating a correlation between the Job Characteristics Model (JCM) and job crafting. It indicates that people are optimally positioned to choose their job alterations and that job attributes influence this process. This study investigates the relationship between the Job Characteristics Model (JCM) and job crafting, which has yet to be extensively studied. By incorporating social support as a variable and utilizing expert data, this study offers a fresh perspective, distinguishing it from most research that primarily depends on employee data. This method provides new perspectives in the field.
Application Performance Management in Software Development
Authors:   IT Programmer Analyst, Department of Technology, Management and Budget Lansing, Michigan, United States of America, Ali Mohammad Nowsher
Published: December 2024

This study investigates the crucial function of Application Performance Management (APM) in software development, emphasizing how it affects teamwork, user pleasure, and application quality. Successful APM procedures are now necessary to guarantee the best possible application performance in a competitive environment as businesses depend increasingly on digital solutions. Examining how APM is changing and how it affects software development processes is the main goal of this research. The study's objectives are to evaluate the efficacy of APM methods, uncover important themes, and point out areas that require more investigation. The main issue addressed is the lack of knowledge on the long-term effects of APM on business results and the difficulties that businesses encounter when implementing APM methods. The approach used in this study is qualitative and is based on secondary data collected from industry reports, expert analyses, and existing literature. The main conclusions show that APM is included in DevOps procedures, proactive monitoring is becoming more prevalent, and user-centric metrics are prioritized. Nonetheless, there are still issues with tool selection and use. One of the limitations of this study is using secondary data, which might not fully represent the subtleties of APM practices. The practical implications emphasize the value of implementing cutting-edge monitoring systems and encouraging teamwork. In contrast, the theoretical implications point to the necessity for additional study into the long-term impacts of APM.
Kehamilan Dini Remaja Kristen: Upaya dan Evaluasi Pendampingannya di Rumah Singgah Griya Welas Asih Semarang
Authors: Minggus Minggus , Amaya Rosa
Published: December 2024

Researchers intend to understand the reasons behind the phenomenon of teenagers experiencing early pregnancy outside of official marriage and provide assistance. How teenagers struggle with self-acceptance and what efforts they make to overcome the tension: between discomfort on the one hand and the urgent need to adapt to environmental demands.  Assistance is carried out by means of observation and interviews. There were 10 Christian teenagers who were accompanied, aged 12-19 years, unmarried, pregnant, and domiciled in the city of Semarang, as well as several cities in Central Java. The results of the assistance showed that the ten teenagers had gone through a period known as a chaotic period, where they felt embarrassed, afraid, confused, and even had the desire to abort their pregnancies. This can be overcome with the support provided by family and close friends. On the other hand, this activity emphasizes the importance of measurable and sustainable assistance so that teenagers have a better perspective and attitude in life than before.
Exploring Business Ethics and Social Responsibility in Tourism Organizations Amid Environmental Changes
Authors: Isabell Virginie , Gregor Irena
Published: December 2024

Purpose: The paper examines the concepts of business ethics and social responsibility in tourism organizations and how these concepts affect their actions and strategies in an era of rapid environmental changes in France. The goal of the study is to investigate the role of ethical operations and social responsibility in organizational performance and sustainability in the tourism industry.Method: A mixed-methods approach including qualitative interviews with key tourism industry leaders and quantitative surveys of employees from different organizations. SmartPLS was used to do Structural Equation Modeling (SEM) analysis, which means that the company included business ethics, social responsibility, managerial behavior, and organizational outcomes in the analysis of statistical significance.Findings: The study finds a positive influence of business ethics on competitive advantage in tourism organizations and an encouraging effect of the practice of social responsibility on customer loyalty. In addition, managerial ethical behavior importantly mediates the connection of organizational culture to employee performance. Impacts of Environmental Changes on Ethical Practices and Organizational Sustainability Relationship.Novelty: This study makes a novel contribution to the field by examining the emerging relationship between business ethics, social responsibility and environmental transformations, specifically in the context of the tourism sector in France. It underscores the importance of ethical leadership and the incorporation of sustainable practices in tourism businesses.Implications: The implications derived from the findings imply that tourism organizations should focus on ethical training, social responsibility in strategies, and sustainability in views of environmental changes for their competitiveness. This information shall be used by the policy makers and leaders of the Industries to prepare more ethical and responsible tourism element