bluuebunny/crossref_metadata_2025 huggingface dataset:
Sustainability Resources of Graduates of Organizations for Orphans and Foster Families with Different Profiles of Emotional Intelligence
Authors: Oslon V.N. , Odintsova M.A. , Semya G.V. , Kolesnikova U.V.
Published: December 2023

The article presents the results of a study of the sustainability resources of graduates of various forms of life arrangements of orphaned children (orphanage and foster family) with different profiles of emotional intelligence (EI): “self-directed EI”, “self-directed EI”, “balanced EI”. It is proved that the profiles of EI, the levels of interpersonal and intrapersonal intelligence do not depend on the conditions of upbringing before graduation, but depend on the gender of the respondent. In girls, the level of EI is reduced more often than in boys, and EI profiles are more often directed at themselves or others, and is less often balanced. It is shown that the most vulnerable is a group with an EI profile directed at others whose sustainability resources are weakly expressed or ambivalent; less vulnerable is a group with an EI profile directed at themselves, whose resources are at an average level; and a group with a balanced EI profile, whose sustainability resources are close to a high level. The targets of assistance for the development of psychological resources of graduates’ resilience, the mobilization of which can ensure successful integration in society, are highlighted. The use of the obtained data in the development of graduate support routes will contribute to the implementation of state policy objectives.
Restriction and Deprivation of Parental Rights in the Context of Enhancing the Social Role of the Family and Strengthening Traditional Spiritual and Moral Values
Authors: Lashkul M.V. , Tarasova A.E.
Published: December 2023

The article is devoted to the problems of implementing the powers of guardianship and guardianship authorities in the field of deprivation and restriction of parental rights, taking a child away from parents, taking into account the orientation towards preserving a child in a blood family, in conditions of strengthening state policy to protect traditional family values, including the category of morality in the system of regulatory regulators of family law, the introduction in the Russian Federation of a ban on changing gender, propaganda of non-traditional sexual relations, preferences and pedophilia. The conducted survey of specialists of guardianship and guardianship authorities (N= 851 people) showed that these issues cause difficulties in applying them in practice and the need to include them in professional development programs. The article presents the results of the analysis of legislative practice, which showed that to date no special procedural regulations have been created for the consideration of such a category of cases. The authors propose to regulate a special procedure for the consideration of such cases by the courts, which should be based on combining legal means, social mechanisms, psychological diagnosis and expertise capable of ensuring socialisation and correction of the most difficult situations, adapting all means of assistance to the family, including temporary placement of the child in alternative families, to the main goal of preserving and reuniting the birth family.
Patients’ Choices for Yoga Therapy: An Exploratory Cross-Sectional, Convenience-Sampling Survey from India
Authors: Telles Shirley , Agnihotri Savita , Sharma Sachin Kumar , Balkrishna Acharya
Published: December 2023

In conventional healthcare, patients’ preferences for their treatment are determined, though this practice has not been reported for yoga therapy. The present convenience sampling exploratory survey attempted to determine whether those seeking yoga therapy would report preferences for the way yoga therapy is implemented, the therapist’s knowledge, and related aspects of yoga therapy. Responses from 426 people attending a yoga therapy institution in India were analyzed. Based on the chi-square test (p < 0.05) and Cramer’s V (> 0.10), most people wished to receive yoga therapy in a group of others with a similar disease (42.25%), in a yoga institution (83.57%), and as in-person sessions (48.83%). Patients preferred yoga therapists to know about the principles of yoga (40.38%), to be well-informed generally (61.97%), and to be able to give suggestions for emotional well-being. For the majority of participants (59.4%), the reason for selecting yoga therapy was “a belief in yoga as therapy” (rather than as an add-on therapy or as a last resort). Patients’ expectations of yoga therapy were positive, namely a cure of disease (79.34%) and improvement after 1 year (95.8%). Most patients (91.6%) wanted their conventional medicine practitioner to know that they were receiving yoga therapy. Although limited by the study design, survey design, and participant details available, overall results suggest that patients (1) reported specific preferences (for the implementation of yoga therapy and for yoga therapists’ knowledge), (2) had expectations of yoga therapy, and (3) most often were interested in their conventional care physicians being informed about the yoga therapy they received.
A Pilot Study of Yoga with Incarcerated Youth Using the Prison Yoga Project Approach
Authors: Ishaq Jennifer , Eyman Kyle , Goncy Elizabeth , Williams Lynn , Kelton Katherine , Knickerbocker Nicholas
Published: December 2023

In recent decades, there has been more significant implementation and research of yoga programs in prisons and correctional facilities. Existing literature suggests that adult and juvenile prison-based yoga programs may improve stress-management and self-regulation skills; reduce depression, anxiety, aggression, and addictive behaviors; and increase prosocial behaviors. However, yoga in juvenile correctional facilities is still understudied compared to adult populations. The Prison Yoga Project (PYP) and Yoga FLAME (Focus, Letting go, Anger management, Mindfulness, and Exhaling negativity) are two frameworks used to structure the implementation of prison-based yoga programs among incarcerated adolescents. The present study aimed to describe trauma-related stress and self-regulation levels in a sample of incarcerated youth and to explore yoga’s effects on developing stress-reduction skills. The study collected measures on overall and in-session stress reduction and baseline self-regulation. Because of the COVID-19 pandemic and public-safety restrictions, the present study was prematurely terminated after 5 months. Only pre-assessment measures were collected. Across time, participants reported a 38% mean stress reduction from the beginning to the end of a yoga session. Incarcerated youth with higher initial self-regulation levels showed higher pre- to post-session improvements in stress. The present findings provide valuable evidence that yoga practice using the combined PYP and FLAME framework can deliver practical benefits to juvenile correctional facilities. Furthermore, yoga may be used to foster rehabilitation, enhance skill development, and facilitate greater success in youth transitioning back into the community.
EVALUATION OF SEED YIELD AND THOUSAND SEED WEIGHT OF CONFECTIONERY SUNFLOWER (Helianthus annuus L.) VARIETIES GROWN BY DIFFERENT FARMING TECHNIQUES IN THE NORTHERN STEPPE OF UKRAINE
Authors: MAKLIAK Kateryna , KORKODOLA Maksym
Published: December 2023

The paper presents data on the seed yield and thousand seed weight of confectionery sunflower (Helianthus annuus L.) varieties cultivated in the Northern Steppe of Ukraine. The study was conducted on three varieties-populations and one F1 hybrid. The study design included two types of basic tillage, three doses of fertilizer, and three plant densities. The seed yield significantly (P = 0.05) depended on the year of testing (the contribution of the year factor to the total variability was 38.88%), plant density (29.30%) and fertilizer dose (14.43%). It also depended on the tillage type (3.01%) and varietal characteristics (0.87%). The highest yield of seeds (up to 4.24 t/ha) was obtained with moldboard plowing, NPK fertilizer doses of 40:60:60 and 60:80:80 and plant density of 40,800 plants/ha. The thousand seed weight significantly (P=0.05) changed under the influence of the year of testing (32.11%), plant density (26.75%) and variety (25.92%), as well as under the influence of fertilization (3.24%) and tillage (3.75%). The largest thousand seed weight (up to 122.3 g) was obtained with moldboard plowing, NPK fertilizer doses of 40:60:60 and 60:80:80 and plant density of 20,400 plants/ha. Recommendations on the farming technique for confectionery sunflower have been drawn up.
A SHORT NOTE ON WATER QUALITY AND SOME BIODIVERSITY COMPONENTS IN GURBAN VALLEY, GIURGIU COUNTY
Authors: VASILESCAETEANU Gina , SANDULESCU Emilia Brindusa , ALISTAR Cristina Florentina , CROITORU Catalin Mihai , MADJAR Roxana Maria , ALISTAR Alexandru , GILEA Gabriel Catalin , STAVRESCU Mala
Published: December 2023

Several field trips were carried out in 2022 and 2023, aiming to investigate the water quality parameters, ichthyofaunal and floristic diversity in some areas of Gurban Valley, located in the protected area Natural Park Comana, Giurgiu County, southern Romania. Throughout the study period were identified fish specimens belonging to nine species: Prussian carp Carassius gibelio (Bloch, 1782); Gobio obtusirostris Valenciennes, 1842; Dnieper chub Petroleuciscus borysthenicus (Kessler, 1859); Roach Rutilus rutilus (Linnaeus, 1758); Danubian spined loach Cobitis elongatoides Băcescu & Mayer, 1969; Belica Leucaspius delineatus (Heckel, 1843); Southern ninespine stickleback Pungitius platygaster (Kessler, 1859); European bitterling Rhodeus amarus (Bloch, 1782) and European mudminnow Umbra krameri Walbaum, 1792. A total of 147 captured specimens were measured, weighed and photographed. For the capture of fish, minnow traps and plankton nets were used, on the Gurban River, right tributary of the Neajlov River, Giurgiu County. The floristic inventory compiled so far included 58 plant species grouped into 31 families, with European, circumpolar, Eurasian, eurasiatic continental or cosmopolitan distribution. Related to physico-chemical characterization of water samples collected from four sampling points (SP), the results of laboratory analysis allowed to frame the water into quality classes and to evaluate if the water meets the requirements for aquatic organisms. Hence, on the basis of nitrite-nitrogen (N-NO2-) and nitrate-nitrogen (N-NO3-) water corresponds to Ist quality class, meanwhile chemical oxygen demand (COD), phosphate-phosphorus (P-PO43-) and ammonium-nitrogen (N-NH4+) allowed to associate water quality with IIIrd class. In addition, it has been found very significant correlations between electrical conductivity (EC) and total hardness (TH) with r=0.9230*** and between pH and TH with r=0.8821***, respectively.
STUDIES ON THE NUTRACEUTIC PROPERTIES OF SOME NATURAL BIO STIMULATING JUICES OBTAINED FROM INDIGENOUS PLANTS AND BEE PRODUCTS
Authors: VLASCEANU Gabriela Antoaneta , PETCULESCU Nicole Livia , ABALARU Cornelia Carmen , POPA Camelia , EREMIA Florentina , BURLACU Georgeta , APETREI Andrei
Published: December 2023

Plants represent an inexhaustible source of organic substances, minerals, vitamins, and antioxidants, which the human body absolutely needs. The opportunity to capitalize on some indigenous plants and bee products in natural, biostimulating juices results primarily from the objective itself, that of obtaining competitive nutritional-therapeutic assortments, with a healthy c effect on consumers. The technology of preparing natural, bio-stimulating juices is not only relatively simple but also affordable. Also, the valorization of the by-products resulting from obtaining these biostimulating natural juices is another important element of economic efficiency. Taking into account their multiple sensory, nutraceutical, and economic characteristics, obtaining bio-stimulating natural juices from indigenous plants and bee products become a major imperative for improving the health status and quality of life for consumers, as well as for the practice of performing national agrotourism.
The relationship of preterm birth with fetal fibronectin level in cervicovaginal fluid and cervical lenght in ultrasonography
Authors: ARPACI Anıl , SOYLU KARAPINAR Oya
Published: December 2023

Objective: In this study, the compatibility between fetal fibronectin determination and the use of cervical length measured by transvaginal ultrasonography of patients who were at risk of preterm birth in the examination performed at 24-34 weeks of gestation, and patients with an increased risk of preterm birth according to the result were defined.

Method: 40 patients who applied to Mustafa Kemal University Training and Research Hospital Gynecology and Obstetrics outpatient clinic between May 2021 and May 2022 were included in the study. Fibronectin results were evaluated using the liquid ELISA method taken from the vaginal secretion by a swap. Cervical lengths were evaluated as 25 mm and below, between 25-30 mm and 30 mm and above in statistical data.

Results: For fFN-positive patients, the preterm delivery rate of patients with a cervical length of 25 mm and less was determined as 100%, while the rate of preterm birth was determined as 77.8% for patients with a cervical length between 25 mm and 30 mm. In addition, the preterm labor rate of fFN-positive patients with a cervical length of 30 mm and above was determined as 78.57%.

Conclusion: All patients with a cervical length of 25 mm or less have a positive fFN test, and a strong correlation can be established between these two values. Accordingly, fFN positivity was found to have a higher sensitivity in determining the probability of preterm delivery compared to the cervical length ratio.
The relationship between age and mortality and morbidity of patients diagnosed with breast cancer: a retrospective clinical study
Authors: DAL M. Burak , TEMİZ Muhyittin
Published: December 2023

Objective: Breast cancer, the most common malignancy among women, is a universally challenging health problem. It is a known fact that the incidence of breast cancer increases with age. In addition, mortality and morbidity increase with age. For now, it does not seem possible to reduce the incidence of breast cancer but it is possible to limit deaths caused by it. Patients are encouraged to get early diagnosis and age-appropriate screening tests. Because regular screening and early diagnosis are very important in improving breast cancer outcomes. Factors such as age, hormonal status and genetics are associated with the incidence of breast cancer. In this study, we aimed to contribute to the literature by examining age-related mortality and morbidity of breast cancer.

Method: This study was carried out at a University Hospital. The sample consisted of 214 women between 01.09.2018/01.09.2022 diagnosed with breast cancer, aged 30 to 80 years.

Results: The mean age of women was 51.9 ± 7.6 years, with 52.8% being
Assessment of relationship between different communication methods and treatment compliance in orthodontic patients during Covid-19 pandemics
Authors: YILMAZ Hakkı , BİLGİÇ Fundagül , KÖSE İlter Burak
Published: December 2023

Objective: The aim of this study was to minimize impairment in oral hygiene and failure of brackets; therefore, effects of pandemic on treatment duration, by communicating our patients using 4 different methods during Covid-19 pandemic.

Methods: In the study, 227 patients undergoing fixed orthodontic treatment were included. Five groups were designed: WhatsApp group, short message service (SMS) group, Teledentistry group, e-mail group and control group. During quarantine period, patients were contacted for 4 times and same text was sent to patients. After pandemics, the patients were assessed using mucogingival index (MGI), orthodontic plaque index (OPI) and failure of brackets was determined.

Results: In MGI, percentage of patients with healthy result were as follows: WhatsApp group, 83.7%; SMS group, 87.8%; Teledentistry group, 83.7%; E-mail group, 77.5%; control group, 72.2% and no significant difference was found (p>0.05). The OPI scores were as follows: 1.12±1.24 in WhatsApp group; 1.27±1.28 in SMS group; 1.24±1.38 in Teledentistry group; 1.00±1.22 in E-mail group; and 1.61±1.25 in the control group and no significant difference was found (p>0.05). The mean number of brackets broken was 0.47±0.88 in WhatsApp group, 0.39±0.83 in SMS group, 0.51±1.00 in Teledentistry group, 0.40±0.67 in E-mail group and 0.44±0.86 in the control group and no significant difference was found (p>0.05).

Conclusion: It was determined that communicating with patients in different ways did not make any difference in terms of the subjects investigated in the study. It was concluded that it would be more appropriate to conduct new studies including social and psychological evaluations.
The development of website games as learning media for 4th-grade elementary students
Authors: Dewi Kadek Kristin Karina , Budiarta Luh Gd. Rahayu , Nitiasih Putu Kerti
Published: December 2023

Abstrak: Penelitian ini bertujuan untuk mengembangkan game website sebagai media pembelajaran untuk siswa kelas 4 sekolah dasar pada semester dua. Metode penelitian yang digunakan dalam penelitian ini adalah desain dan pengembangan (D&D) oleh Richey & Klein (2007) dengan model ADDIE (analisis, desain, pengembangan, implementasi, dan evaluasi). Terdapat beberapa instrumen penelitian yang digunakan dalam proses pengambilan data, yang bernama panduan wawancara kepada guru bahasa Inggris, lembar observasi untuk mengobservasi proses pembelajaran di kelas, analisis dokumen dalam bentuk modul pembelajaran dan alur tujuan pembelajaran, lembar penilaian ahli untuk ahli pendidikan, dan lembar kuesioner pengguna untuk guru dan lima siswa sekolah dasar kelas 4. Hasil penelitian ini adalah prototype game website. Hasil dari analisis data menunjukkan bahwa prototype game website dikualifikasi sebagai media yang sangat valid. Oleh karena itu, game website ini layak untuk digunakan sebagai media pembelajaran untuk siswa kelas 4 sekolah dasar.Abstract: This study aims to develop a website game as learning media for 4th-grade elementary students in the second semester. The subjects of this study were 4th-grade elementary students and an English teacher. The research method used is design and development (D&D) by Richey & Klein (2007) using ADDIE (analysis, design, development, implementation, and evaluation) mode. Several research instruments were used in the data collection process, namely interview guides for English teachers, observation sheets to observe the learning process in the classroom, documents analysis in the form of teaching modules and objective learning flow, expert judgment sheet for the educational experts, user questionnaire sheet for the teacher and five 4th-grade elementary students. The outcome of this research is a website game prototype. The results of the data analysis show that the website game prototype qualified as a very valid product. Therefore, this website game is feasible to use as a learning media for 4th-grade elementary students.
PENGEMBANGAN LEARNING MANAGEMENT SYSTEM BERBASIS MOODLE UNTUK FAKULTAS SAIN DAN TEKNOLOGI UIBU
Authors: Tjipta Dwi Sagitta , Cholis Mohammad Nur , Arisandi Arisandi , Dewantari Arinta Agnie
Published: December 2023

Pendidikan harus mengakomodasi teknologi untuk meningkatkan kualitas pembelajaran sehingga menghasilkan lulusan berkualitas dengan pembelajaran efektif dan efisien. Salah satu penerapan caranya adalah pembelajaran blended learning yang merupakan penyempurnaan pembelajaran konvensional tatap muka di kelas dengan memanfaatkan pembelajaran jarak jauh sebagai pendukung kegiatan di kelas, sehingga waktu belajar semakin panjang dan mahasiswa bisa mengembangkan diri untuk menguatkan pemahamannya selama di rumah. Blended learning memanfaatkan Learning Management System (LMS) sebagai fasilitas untuk mendukung pembelajaran. LMS meliputi perencanaan, penggunaan ulang materi pembelajaran, dan evaluasi pembelajaran. Salah satu LMS yang banyak digunakan untuk pembelajaran adalah Moodle yang sudah mendukung fitur-fitur yang dibutuhkan untuk LMS.Pengembangan LMS untuk mendukung pembelajaran pada Program Studi S1 Teknik Mesin, S1 Teknik Elektro, S1 Teknik Kimia Fakultas Sain dan Teknologi (FST) Universitas Insan Budi Utomo (UIBU), meliputi: perencanaan, pelaksanaan, evaluasi, dan rekapitulasi hasil evaluasi pembelajaran. LMS ini diterapkan dengan pendekatan konstruktivisme untuk memperkuat kemampuan kognitif mahasiswa, dengan model pembelajaran yang digunakan adalah Problem Based Learning yang didukung LMS (Blended Learning). Uji LMS ini meliputi uji kelayakan yang dilakukan oleh Kaprodi S1 Teknik Mesin, S1 Teknik Elektro, dan S1 Teknik Kimia FST UIBU yang menyatakan bahwa pengembangan LMS ini efektif dan fungsional dalam mengakomodir pembelajaran pada semua Prodi FST UIBU.Kata kunci—Learning Management System, Moodle, pembelajaran
Prognostic Role of Myocardial Flow Reserve in Heart Failure With Preserved Ejection Fraction
Authors: Kopeva K. V.
Published: December 2023

Aim      To study the role of myocardial blood flow (MBF) and myocardial flow reserve (MFR) in patients with heart failure with preserved ejection fraction (HFpEF) in stratifying the risk of HFpEF progression during 12 months of follow-up.

Material and methods  The study included 58 patients with non-obstructive coronary artery disease and HFpEF. Concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured using an enzyme-linked immunosorbent assay. MFR and MBF were determined by dynamic single-photon emission computed tomography of the myocardium.

Results At 12 months, the patients were divided into two groups: group 1 (n=11) included patients with an unfavorable course of HFpEF, group 2 (n=47) included patients with a favorable course. A multivariate analysis showed that NT-proBNP concentrations (odds ratio (OR), 3.23; 95% confidence interval (CI), 1.76-6.78; p=0.008) and MFR (OR, 8.09; 95% CI, 5.12-19.98; p<0.001) were independent predictors of adverse outcomes. According to ROC analysis, values of MFR ≤1.62 (area under the curve (AUC)=0.827; p<0.001) and NT-proBNP ≥760.5 pg/ml (AUC=0.708; p=0.040) can be considered as markers for HFpEF progression. Furthermore, the combined measurement of NT-proBNP concentration and MFR had a higher prognostic significance (AUC, 0.954; p<0.001).

Conclusion      Values of NT-proBNP and MFR can be used as noninvasive markers for an unfavorable course of HFpEF, and their combined measurement increases the prognostic significance.
Cardiometric assessment of visual stimuli to identify likely reactions to destructive network content
Authors: Brodovskaya E.V. , Dombrovskaya A.Y. , Kravchuk I.D. , Likhacheva E.V. , Lukushin V.A. , Nikolaeva L.P. , Ognev A.S. , Parma R.V.
Published: December 2023

The article presents the experimental confirmation of the hypothesis that with the help of cardio- and oculometric attestation of various types of visual content, it is possible to conduct a selective analysis of the stimulus material used in projective diagnostics and to identify a group of images most suitable for operative counseling, and also shows that there is often an increased interest in content that symbolizes the value of rivalry and risky forms of behavior, with a high degree of probability, will correlate with the rapid manifestation of the respondent's dissatisfaction with various kinds of restrictions on their own behavior.
Clinical and epidemiological features of the detection and course of the infectious disease tuberculosis depending on the presence of concomitant pathology
Authors: Davletbaeva N.V. , Sharipov R.A. , Daminov E.A. , Davletbaev R.N. , Tyulkova T.E.
Published: December 2023

The article is devoted to the most pressing issues of studying the clinical and epidemiological features concerning the detection and course of tuberculosis infection in patients with concomitant pathologies. Such pathologies include cancer, diseases of the endocrine system, of the respiratory system (chronic bronchitis, pneumoconiosis), gastric ulcer, pathology of the urinary system, exhaustion due to insufficient nutrition, smoking. Using genetically engineered biological drugs (GEBPs) in practice reduces the activity of inflammatory phenomena due to suppression of the immune response, but increases the risk of developing infectious diseases, primarily tuberculosis. Immunosuppressive therapy in organ transplant patients is also associated with the risk of developing tuberculosis. A special nature of immune disorders develops during HIV infection, a comorbid disease in patients with tuberculosis. The diseases listed above create a medical risk group in patients with immunocompromise, which is the basis for the development of tuberculosis. In addition to the risk of developing infection, patients with concomitant diseases have unfavorable results from treatment of tuberculosis, which does not allow achieving abacillation in a short time, thereby maintaining a reservoir of infection in society. In this regard, the purpose of our research was to study the clinical and epidemiological features of the detection and course of tuberculosis infection in patients with concomitant pathology A study was conducted using a continuous sampling method for the period from December 2020 to August 2021. 67 medical records of an inpatient at the state budgetary healthcare institution “Republican Clinical Anti-TB Dispensary” (Ufa) were analyzed. The groups were formed based on the detection of concomitant pathology (main, n=33) and its absence (control, n=34). To achieve the goal of the study, a comparative analysis of methods for detecting tuberculosis and clinical manifestations of tuberculosis was performed; prevalence of the process, detection of the fact of bacterial excretion and drug sensitivity from December 2020 to August 2021. 67 case histories of Mycobacterium tuberculosis (MBT) in patients of the studied groups were analyzed. Statistical data processing was performed using licensed software Statistica 6.0 when calculating two types of data: discrete and interval. To assess the chances of detecting the studied factor in both groups, the indicator (OR) was used to calculate the 95% confidence interval (CI). Interval indicators were studied by t-test for independent samples, with Livigne's correction.
Effectiveness of Manchester triage flow model regarding patients’ waiting time in Bahria international hospital Lahore, Pakistan
Authors: Shaheen M. , Afzal M. , Mukhtar M.
Published: December 2023

The triage system is meant to be implemented in all (Accidental & Emergency Departments) so as to help and determine the relative priority of individual patient needs. Emergency patients are to be given immediate treatment, while those with non-acute symptoms may have to wait longer (Lucke et al., 2021). Assessment process during the triage need to be balanced with the extent of patient flow, as expanding the assessment process during triage may slow down the patient flow and may lead to delay in emergency service provision (Lucke et al., 2021).Through the use of computer-generated reports, archival data records for two months from the ED of the Bahria International Hospital in Lahore, Pakistan to assess the effectiveness of patients triage flow model. The results of this quantitative study showed that the patient flow model had a considerable temporal effect. Including 16 females, 25 were male and 25% average waiting was more than 240 mints. The ability to decrease patient wait times while enhancing patients quality of care and health outcomes is one of the social change implications. A quantitative study would produce data that would assist medical staff by shortening the wait times for patients.
MORPHOLOGICAL ASPECTS OF DEVELOPMENT OF MALIGNANT TUMORS UNDER THE CONDITIONS OF COMORBID PATHOLOGY AND MITOCHONDRIAL THERAPY
Authors: Kit O.I. , Shikhlyarova A.I. , Frantsiyants E.M. , Kaplieva I.V. , Neskubina I.V. , Zhukova G.V. , Bandovkina V.A. , Surikova E. , Trepitaki L.K.
Published: December 2023

Morphological studies represent the most important part of evidence-based medicine, and in oncology they are an essential attribute in the diagnostics of malignant neoplasms. In experimental oncology, current models of the tumor growth are developed to be as close as possible to the actual biological life conditions. There is a need to study the pathogenesis of tumors in various variants of their orthotopic growth, the formation of bi-model systems with a combination of the malignant growth and comorbid conditions (chronic neurogenic pain, diabetes mellitus, hypothyroidism, obesity), the use of subcellular substrates for the induction of carcinogenesis and biotherapy. Among the important methods for studying the pathogenesis of tumors, morphology is on a par with advanced molecular genetic and biochemical methods, as well as radioimmunoassay techniques.Morphological studies represent the most important part of evidence-based medicine, and in oncology they are an essential attribute in the diagnostics of malignant neoplasms. In experimental oncology, current models of the tumor growth are developed to be as close as possible to the actual biological life conditions. There is a need to study the pathogenesis of tumors in various variants of their orthotopic growth, the formation of bi-model systems with a combination of the malignant growth and comorbid conditions (chronic neurogenic pain, diabetes mellitus, hypothyroidism, obesity), the use of subcellular substrates for the induction of carcinogenesis and biotherapy. Among the important methods for studying the pathogenesis of tumors, morphology is on a par with advanced molecular genetic and biochemical methods, as well as radioimmunoassay techniques.
STRESS IN PATHOGENESIS OF DEVELOPMENT OF TUMOR PATHOLOGY OF THE THYROID GLAND
Authors: Zima D.V. , Khabarov O.R. , Bezrukov O.F. , Zyablitskaya E.Yu.
Published: December 2023

Our experience in the endocrine surgery at our clinics institution has shown a relationship between the appearance of nodules in the thyroid gland and a long-term exposure to stress. At present, the complicated geopolitical circumstances play a role of an active stressor, and until recently, it was also the COVID-19 pandemic, which caused a change in lifestyle, heavy material losses, and loss of loved ones. Oncogenic activity of cells is reflected in an imbalance of markers of proliferation and apoptosis. Many researchers associate thyroid pathology with molecular alterations as diagnostic markers (Styazhkina S.N., 2017; Romashchenko P.N. et al., 2021).
YETENEK YÖNETİMİ VE ÖRGÜTSEL BAĞLILIK İLİŞKİSİNDE İŞVEREN MARKASININ ARACI ROLÜNÜN İNCELENMESİNE YÖNELİK BİR ARAŞTIRMA
Authors: ERDEM Hüseyin Aykut , BOZKURT Serdar
Published: December 2023

Sürdürülebilir rekabet avantajı kaynağı olan çalışanların elde tutulması için yetenek yönetimi uygulamaları ve işveren markası çalışmaları önem arz etmektedir. Bu faaliyetleri dikkate alan organizasyonların, çalışanlarının kurumlarına olan bağlılıklarının artacağı düşünülmektedir. Araştırma, farklı sektörlerde çalışanların yetenek yönetimi uygulamalarına yönelik algılamaları ile örgütsel bağlılıkları arasındaki ilişkide, işveren markasının aracı rolünü incelenmesini amaçlamaktadır. Böylelikle, organizasyonlar açısından rekabet avantajı kaynağı olarak görülen çalışanların, organizasyona çekilmesi ve elde tutulması için olası unsurların neler olabileceği tespit edilebilecektir. Araştırmada, kavramlar arası ilişkiler sosyal değişim ve sosyal kimlik teorileri kapsamında incelenmiştir. Bu çerçevede, insan kaynakları uygulamalarından yetenek yönetimi faaliyetlerinin örgütsel bağlılık ile ilişkisi işveren markasının rolü bağlamında ele alınmıştır. Araştırma kapsamında, 375 çalışana yönelik bir anket çalışması düzenlenmiştir. Anket formu; yetenek yönetimi uygulamaları, işveren markası ve örgütsel bağlılık kavramlarını ölçecek ifadelerle birlikte, demografik nitelikleri belirleyen sorulardan oluşmaktadır. Araştırma sonucunda, çalışanların yetenek yönetimi uygulamalarına yönelik algılamaları ile örgütsel bağlılıkları arasındaki ilişkide, işveren markasının kısmi aracılık rolünün olduğu tespit edilmiştir. Ayrıca yetenek yönetimi uygulamalarının, örgütsel bağlılığa etkisi tespit edilirken aynı zamanda çalışanların işveren markasının algılamalarının örgütsel bağlığa etkisi de bulunmuştur.
Mental optometry: Perceive to see with the mind’s eye
Authors: Ali Jamshed , Dubey Gaurav , Hayat Zeba , Das Prasenjit , Afroz Simi
Published: December 2023

Mental optometry is a newly recognized word that refers to the interaction of the mind, brain, and sensory perceptions. The pattern established by behavioural optometry's research and assumption linking bodily orientation to the physical field of vision will be followed by the mind's eye, emotions, and actions. All three theories imply the presence of such an idea as a fundamental component of their systems, even if it isn't formally stated. The database was compiled using PubMed, PubMed Central (PMC), the Cochrane library, Google scholar, and research gate. Mental Optometry provides a neurobiologically informed knowledge of mood, emotion, and thinking. Visual stimulus interpretations, enabling for therapeutic treatments to help patients recognize and rectify skewed judgments. Optometrists have an important role in patients with mental illness. Finally, we must evaluate how enhancing ocular health and visual suppleness may assist our patients improve their overall feeling of well-being.
Impact of prednisolone, dexamethasone, and fluorometholone eye drops on intraocular pressure in patients post-cataract surgery: A randomized controlled study
Authors: Abhilash  , Somayaji Sharmila , Gore Sangeetha R , Srinivasa K  , Maurya Rajendra P
Published: December 2023

After cataract surgery, topical corticosteroids are prescribed for inflammation reduction, but prolonged use may lead to side effects like steroid-induced glaucoma. These steroids can elevate intraocular pressure (IOP), and if elevated IOP isn't promptly addressed, it may advance to glaucoma. Vigilant monitoring of IOP changes is crucial for early detection and intervention, forming the basis for this study.The objective of this study was to evaluate and compare the impact of post-cataract surgery administration of eye drops containing prednisolone, dexamethasone, and fluramethalone on Intra-Ocular pressure (IOP) in patients.

Seventy-five patients were randomly allocated to three groups, each comprising thirty individuals. Participants were administered prednisolone, dexamethasone, and fluramethalone eye drops, respectively, with a tapered dosage over a 42-day period. The study involved documenting intraocular pressure (IOP) measurements both before and after the surgery. Subsequently, patients were monitored for a duration of three months.

Among the 75 patients, approximately 5.77% (n = 4) exhibited an increase in intraocular pressure (IOP) of ≥10 mmHg from their baseline. A moderate elevation in IOP (≥5 mmHg) was observed in about 13.44% (n = 13) of the patients. Notably, a clinically significant rise in IOP, defined as an increase of ≥10 mmHg and an overall IOP of ≥20 mmHg, occurred in 4.98% (n = 4) of the patients, all of whom were in the fluramethalone group. The mean post-operative IOP differed significantly among the three treatment groups.

Fluromethalone possesses a heightened propensity to induce an early and substantial increase in intraocular pressure (IOP), necessitating careful and vigilant usage with continuous monitoring.
Clinical assessment of corneal complications of manual small incision cataract surgery at tertiary care centre
Authors: Yamini K  , Usha B. R
Published: December 2023

: To assess corneal complications and visual outcome of manual small incision cataract surgery.

: This study comprises of 227 patients in a tertiary care centre in Kolar district, who underwent MSICS were examined for corneal complications and visual outcome postoperatively on Day 1, 1 week, and at the end of 6 week also visual acuity (VA) assessment, anterior segment evaluation with slit lamp biomicroscopy, posterior segment evaluation using indirect ophthalmoscopy, and keratometry was done.

227 participants were included in the study, of whom 138 (61%) were female and 89 (39%) were male. The maximum number of patients being in the age group of 61-70 (42.7%). OCTET grading was done for corneal edema patients and on post op Day 1, total 62 patients who had corneal edema in the study were graded according to OCTET classification, and 6 patients (9.6%) had grade 1, 17 patients (27.4%) had grade 2 and 39 patients (63%) had grade 3. At the end of 6 week postoperatively, 45 patients had clear cornea, and 5 patients (8%) had grade 1, 6 patients (9.5%) had grade 2, and 7 patients (11.1%) had grade 3, and 82.3% of patients had VA of 6/6 to 6/9 followed by 11% had 6/12 to 6/18 and 6.6% had 6/24 to 6/36.

: Small incision cataract surgery is most cost-effective surgery if corneal endothelium is protected during surgery and will have early visual rehabilitation.
Effect of pan retinal photocoagulation on macular ganglion cell - inner plexiform layer and peripapillary retinal nerve fibre layer thickness
Authors: Mishra Priyadarshini , Kanaujia Vikas , Sharma Kumudini , Mishra Prabhaker
Published: December 2023

: To determine the effect of pan retinal photocoagulation (PRP) on spectral domain optical coherence tomography (SD OCT) morphologic parameters like macular ganglion cell-inner plexiform layer (GCIPL), peripapillary retinal nerve fibre layer (RNFL) thickness and central macular thickness (CMT) in diabetic retinopathy cases.

This is a retrospective study including 52 eyes with severe non-proliferative to proliferative diabetic retinopathy without macular oedema who required PRP. Macular GCIPL, CMT and peripapillary RNFL thickness measured at baseline and at 1-, 6-, 12- and 18-months post PRP with SD OCT.

CMT, Macular GCIPL and peripapillary RNFL thickness increased significantly at 1 month (p<0.05), thereafter a decreasing trend noted at 6, 12 and 18 months. At 18 month CMT, GCIPL and RNFL thickness are higher than baseline but not statistically significant except temporal RNFL and Average GCIPL (p<0.05). A significant correlation found between changes in temporal RNFL and average GCIPL thickness (Pearson Correlation coefficient r= 0.652, 0.557, 0.782, 0.624 at 1, 6, 12 and 18 months respectively. P<0.05 for all values)

CMT, macular GCIPL and peripapillary RNFL thickness increase following PRP; peaking at month 1 and stabilizing through next 18 months. Macular GCIPL thickness could be a reproducible indicator of temporal RNFL.
Study of OCT based biomarkers as a predictor of visual outcome in diabetic macular edema
Authors: Kaur Rajwinder , Sidhu Tanvir , Gupta Priyanka , Dahiya Priyanka , Aggarwal Anupriya , Singla Ritesh
Published: December 2023

To determine the association between optical coherence tomography (SD-OCT) based biomarkers and visual acuity (VA) in diabetic macular edema (DME).

This cross-sectional study was conducted at a tertiary care teaching hospitalbetweenJanuary 2021 and July 2022.The study included 54 eyes (30 patients) with DME. Based on the early treatment diabetic retinopathy study (ETDRS) grading system, these were classified as mild (n=1), moderate (n=31), severe (n=14), and very severe (n=8) non-proliferative diabetic retinopathy (NPDR). The demographics, VA recorded using ETDRS chart and ETDRS scoring system, slit lamp biomicroscopy findings, colour fundus pictures and biomarkers determined using macular scans on SD-OCT were noted. Six eyes with proliferative diabetic retinopathy (n-4) and considerable media opacity (n-2) were excluded. The data was entered into Microsoft Excel spreadsheet 2021and IBM's SPSS 26 statistical program was used to calculate the results.

VA and biomarkers, which included central macular thickness, disorganisation of retinal inner layers (DRIL), ellipsoid zone disruption (EZD), choroidal thickness were measured on SD-OCT.

: The mean age was 59.4±9.4 years, and male to female ratio was 1.3:1. Mean uncorrected and best corrected VA were 46 and 61 letters, 55.12±1.76 and 67.25±10.05 letters for moderate NPDR, 43.07±3.95 and 52.14±17.83 letters for severe NPDR, and 26.50±16.53 and 36±16.38 letters for very severe NPDR, respectively. VA deteriorated with increasing disease severity. Poorer VA was associated with increased average foveal and macular thickness and increased mean horizontal disruption of the inner retinal layers (DRIL). Average choroidal thickness positively correlated with increasing DR severity.

: Poorer VA was associated with increasing DR severity, increased central retinal thickness, increased mean horizontal DRIL and increased average foveal choroidal thickness. We found no statistically significant correlation between VA and ellipsoid zone disruption.
A cross-sectional study to evaluate ocular manifestations in chronic kidney disease patients in a tertiary care centre
Authors: Sangeetha T  , K Yamini  , Kumar H Mohan , Kanthamani K  , Athish K K  , Mohamad Raheel
Published: December 2023

Chronic kidney disease (CKD) constitutes a major healthcare issue due to defective microcirculation secondary to systemic hypertension and diabetes mellitus. Hence, the aim is to find the prevalence of ocular pathology, risk factors and its association with the level of kidney function in patients with CKD undergoing haemodialysis.

This prospective, cross-sectional study included 105 CKD patients referred to Ophthalmology Department in a tertiary care centre from November 2021 to April 2023. They were evaluated for demographic data, history of systemic comorbidities, visual acuity and ocular pathologies. This was correlated with the stages of CKD which is defined as the presence of glomerular filtration rate (GFR) < 60 mL/min/1.73 m2 and/or proteinuria. Chi-square test or Fischer’s exact test was used as test of significance for qualitative data and Independent t test was used as test of significance to identify the mean difference between two quantitative variables. ANOVA was used as test of significance to identify the mean difference between more than two quantitative variables.

Out of 105 [74 (70.5%) male and 31(29.5%) females] CKD patients with mean age 58.43±13.05, ocular pathology was noted in 63 (60%) with hypertensive retinopathy in 47 (44.76%), diabetic retinopathy in 38 (36.19%), mixed retinopathy in 24 (22.85%), cataract in 24 (22.85%), glaucomatous changes in 5 (4.76%), ARMD in 4 (3.8%) and retinal vein occlusion in 3 (2.85%). The mean platelet volume also showed positive correlation with worsening stages of CKD (P-0.015), Hypertensive and diabetic retinopathy (P<0.001).

Higher prevalence of ocular pathology 63 (60%) was observed in this study, re-emphasising that ocular screening is mandatory in all chronic kidney disease patients for early detection and initiation of prompt treatment to prevent ocular morbidity.
Schnyders corneal dystrophy: A case report
Authors: Israel Mervin Jonathan , Wali Keerti
Published: December 2023

Schnyder corneal dystrophy (SCD) is a rare, autosomal dominant inherited dystrophy affecting the anterior stroma of the cornea. It is caused by a local metabolic defect mapped on the UBIAD1 gene chromosome 1p36. It is known to causes progressive bilateral opacification of the cornea due to an abnormal accumulation of phospholipids and cholesterol in the cornea. In our case a 22-year-old male with vision loss and ocular discomfort revelled multiple grey, infiltrates or disc like opacities in both eyes arranged in circinate manner on slit-lamp, involving the sub-epithelium and stroma. On anterior segment OCT, involvement of the entire stroma was noted with Increased deposits seen in the anterior 1/3rd of the stroma. Central corneal thickness was also increased in the areas of depositions, while systemic evaluation showed dyslipidemia. Clinical as well as anterior segment OCT findings suggest of intrastromal deposits in a ring like pattern, suggestive of schnyders corneal dystrophy. AS-OCT is vital in such cases to help differentiate epithelial involvement from stromal, thus altering the therapeutic approach. Patients can be planned for penetrating keratoplasty if visual acquits is affected.
The Relationship Between Senior Learners’ In-Class Willingness to Communicate in English, Intrinsic Motivation, Foreign Language Enjoyment, Classroom Environment, and Teacher Immediacy
Authors: Borkowska Anna
Published: December 2023

The primary objective of this paper is to explore age-advanced learners’ in-class willingness to communicate (WTC) in English, as well as to determine the relationship between WTC, intrinsic motivation (IM), foreign language enjoyment (FLE), classroom environment (CE), and teacher immediacy (TI). The instrument used was a questionnaire comprising biodata items and five adapted scales.
The statistical analysis revealed that the third age students’ WTC was higher in meaning-focused tasks than in form-focused, which indicates that the older adults paid due attention to dyadic activities based on authentic communication. The strongest and most positive correlation was found between CE and TI, suggesting that the teacher played a crucial role in creating a supportive classroom environment. Moreover, the data showed a moderate correlation between WTC and FLE, WTC and CE, as well as WTC and TI. This basically means that, in order to boost the older learners’ WTC, a language instructor ought to provide room for establishing bonds between their students, which, in turn, may produce positive emotions that encourage learners to engage in active classroom interactions.
The Entanglement of Disability, Animality and Humanness in Indra Sinha’s Animal’s People in the Light of Sunaura Taylor’s Ethical Theories
Authors: Filipczak Iwona
Published: December 2023

One recent development in the field of disability studies is its intersection with animal studies, as represented in the work of American artist, writer, disability and animal rights activist Sunaura Taylor. In her art and scholarly works, primarily in her book Beasts of Burden (2017), Taylor examines the porousness of human/nonhuman categories in the context of disability studies. Although Taylor is aware of how various discourses animalized certain populations in the past (the colonized, ethnic minorities, or people with disabilities), she insists on showing resemblance and kinship between disabled people and animals. Taylor’s ideas seem to be reflected in Indra Sinha’s Animal’s People (2007), which deals with the problem of environmental catastrophe, consequent health issues of the local population, and animalization of people with disabilities. The paper investigates Sinha’s portrayal of entanglements of the human with the nonhuman in the material sphere, and the emergence of a new type of consciousness, based on a redefinition of one’s connection to the world, which involves reclaiming one’s animality.
Sir Gawain’s Deeds of Arms: The Middle English Romance as Martial Instruction
Authors: Grabowski-Górniak Przemysław
Published: December 2023

Recent decades have witnessed a growing interest in medieval European martial arts, resulting in scholars, and martial arts practitioners studying historical fencing treatises in hopes of recreating combat systems of the period. Unfortunately, none such treatises of English origin survive. However, a well-documented history of cultural and material exchange between the Continent and England, suggests that a careful examination of selected Middle English romances may unveil a literary record of a possible transmission of those martial systems to England. As one analyses the depictions of formal combat in assorted Middle English romances devoted to the exploits of Sir Gawain it becomes evident that some of them bear an uncanny resemblance to the contents of certain continental fight books. Such comparison may reveal a particular role Sir Gawain may have had in the English chivalric tradition, that of a purveyor of martial teachings and an instructive model of the performative mode of chivalry.