bluuebunny/crossref_metadata_2025 huggingface dataset:
Metabolic, Intestinal, and Cardiovascular Effects of Sotagliflozin Compared With Empagliflozin in Patients with Type 2 Diabetes: a Randomized, Double-Blind Study
Authors: Posch Maximilian G. , Walther Niklas , Ferrannini Ele , Powell David R. , Banks Phillip , Wason Suman , Dahmen Raphael
Published: July 2022

  

OBJECTIVE

Inhibiting sodium glucose cotransporters (SGLT) improves glycemic and cardiovascular outcomes in patients with type 2 diabetes (T2D). We investigated the differential impact of selective SGLT2 inhibition and dual inhibition of SGLT1 and SGLT2 on multiple parameters.

RESEARCH DESIGN AND METHODS

Using a double-blind, parallel-group design, we randomized 40 patients with T2D and hypertension to receive the dual SGLT1 and SGLT2 inhibitor sotagliflozin 400 mg or the selective SGLT2 inhibitor empagliflozin 25 mg, with pre-existing antihypertensive treatment, for 8 weeks. In an in-house testing site, mixed meal tolerance tests (MMTTs) and other laboratory and clinical evaluations were used to study metabolic, intestinal, cardiovascular, and urinary parameters over 24 hours.

RESULTS

Changes from baseline in glycemic and blood pressure control; intestinal, urine, and metabolic parameters; and cardiovascular biomarkers were generally similar with sotagliflozin and empagliflozin. During the breakfast MMTT, sotagliflozin significantly reduced incremental area under the curve (AUC) values for postprandial glucose, insulin, and glucose-dependent insulinotropic polypeptide (GIP) and significantly increased incremental AUCs for postprandial glucagon-like peptide 1 (GLP-1) relative to empagliflozin, consistent with sotagliflozin-mediated inhibition of intestinal SGLT1. These changes waned during lunch and dinner MMTTs. Both treatments significantly lowered GIP incremental AUCs relative to baseline over the 14-hour MMTT interval; the most vigorous effect was seen with sotagliflozin soon after start of the first meal of the day. No serious or severe adverse events were observed.

CONCLUSIONS

Changes from baseline in glycemic and blood pressure control, cardiovascular biomarkers, and other parameters were comparable between sotagliflozin and empagliflozin. However, sotagliflozin but not empagliflozin inhibited intestinal SGLT1 after breakfast as shown by larger changes in postprandial glucose, insulin, GIP, and GLP-1 AUCs, particularly after breakfast. Additional study is warranted to assess the clinical relevance of transient SGLT1 inhibition and differences in incretin responses.  
Undiagnosed diabetes in US adults: Prevalence and Trends
Authors: Fang Michael , Wang Dan , Coresh Josef , Selvin Elizabeth
Published: July 2022

  

Objective: Confirmatory testing is recommended for diabetes diagnosis in clinical practice. However, national estimates of undiagnosed diabetes are based on single elevated test measures, potentially resulting in overestimation. Our objective was to update trends in undiagnosed diabetes using definitions consistent with clinical practice.

Research Design and Methods: We included 30,492 adults (aged≥20 years) from the National Health and Nutrition Examination Survey (1988-2020). Among adults without diagnosed diabetes, confirmed undiagnosed diabetes was defined as having both elevated fasting plasma glucose (FPG) (≥126 mg/dl) and elevated glycated hemoglobin (HbA1c) (≥6.5%), and persistent undiagnosed diabetes was defined as having elevated HbA1c or FPG, adjusted for the within-person variability in HbA1c and FPG tests.

Results: From 1988-1994 to 2017-2020, there was an increase in the prevalence of diagnosed diabetes (4.6% to 11.7%), but no change in prevalence of persistent undiagnosed diabetes (2.23% to 2.53%) or confirmed undiagnosed diabetes (1.10% to 1.23%). Consequently, the proportion of all diabetes cases that was undiagnosed declined from 32.8% to 17.8% (persistent undiagnosed diabetes) and 19.3% to 9.5% (confirmed undiagnosed diabetes). Undiagnosed diabetes was more prevalent in older and obese adults, racial/ethnic minorities, and those without healthcare access. Among persons with diabetes, Asian-Americans and those without healthcare access had the highest proportion of undiagnosed cases, with rates ranging from 23% to 61%.

Conclusion: From 1988-2020, the proportion of diabetes cases that was undiagnosed declined substantially, suggesting major improvements in diabetes screening and detection. Undiagnosed diabetes currently affects 1-2% of US adults, up to 90% of all cases are diagnosed. 
Longer Daily Duration of Supervised Rehabilitation after Laparoscopic Surgery for Colorectal Cancer Improves Activities of Daily Living
Authors: Tani Takuaki , Imai Shinobu , Fushimi Kiyohide
Published: July 2022

Objective: To evaluate the effect of a supervised rehabilitation programme with longer hours per day on activities of daily living after laparoscopic surgery for colorectal cancer.Design: This study represents retrospective observational use of nationwide administrative data.Patients: Eligible patients (n = 8,633) were first diagnosed with colorectal cancer between 1 April 2017 and 31 March 2018, underwent laparoscopicassisted colorectal resection, and began rehabilitation within 3 days of surgery.Methods: Patients underwent a long (40 min or more) or short (less than 40 min) supervised rehabilitation programme, defined as rehabilitation under physiotherapist and occupational therapist supervision. The main outcome measure was improvement in activities of daily living from postoperative day 0 to day 14 using Nursing Need Degree.Results: Patients who underwent longer daily supervised rehabilitation (n = 7,173) showed greater improvements in activities of daily living at 14 days after laparoscopic surgery than patients who underwent shorter daily supervised rehabilitation (n = 1,460) (odds ratio (95% confidence interval; 95% confidence interval): 1.42 (1.22–1.64), p < 0.001). The rate of postoperative complications did not differ between groups.Conclusion: Longer daily supervised rehabilitation for colorectal cancer improves activities of daily living after laparoscopic surgery.
LAY ABSTRACTPost-operative rehabilitation is performed for muscle weakness, decreased range of motion of joints, and pain caused by surgery, in order to promote recovery and help patients with activities of daily living after surgery. Supervised rehabilitation provides the patient with a programme based on their postoperative condition and background. Laparoscopic surgery for colorectal cancer, the focus of this study, is minimally invasive and results in less postoperative decline than other surgeries. The aim of this study was to evaluate the effect of a supervised rehabilitation programme with longer daily duration on the ability of patients (n = 8,633) to perform activities of daily living after laparoscopic surgery for colorectal cancer. The results show that engaging in daily supervised rehabilitation for longer duration (40 min or more) after laparoscopic surgery for colorectal cancer improves activities of daily living.
Cambios post mortem en la calidad de carne de peces amazónicos de las especies Piaractus brachypomus, Arapaima gigas, Brycon amazonicus, Pseudoplatystoma punctifer, Colossoma macropomum. Revisión bibliográfica.
Authors: Enriquez Estrella Miguel Angel
Published: July 2022

Este trabajo se realizó a partir de la revisión bibliográfica de documentos publicados, sobre la influencia de los cambios post mortem de cinco especies de peces amazónicos (Piaractus brachypomus, Arapaima gigas, Brycon amazonicus, Pseudoplatystoma punctifer, Colossoma macropomum) en la calidad de la carne. El objetivo se centró en revisar aquellos artículos que presentan información sobre los cambios físicos, químicos y microbiológicos que suceden en la carne y algunos métodos de conservación que existen, se han seleccionado un total de 33 artículos de los cuales 18 son en inglés, 5 en portugués y 10 en español. Los resultados obtenidos destacan la importancia del frío en la conservación de las especies, así como el manejo de atmósferas modificadas que regulan la degradación que se genera por el cambio post mortem, en conclusión, el sacrificio, el manejo y la conservación tienen mucho efecto en la calidad del producto.
Self-reference Lock-in Thermography for Detecting Defects in Metal Bridge Spans
Authors: Solovyev A. L. , Royak M. E.
Published: July 2022

Introduction. Incipient fatigue damage in the metal superstructures of bridges creates certain threats to the safety of operation. Various methods of non-destructive testing are used for their timely detection and diagnosis. A modern and popular on-the-day solution is the method of infrared (IR) thermography. Due to the specifics of the operation of IR cameras, additional processing of recordings received from these cameras is required to obtain an accurate result. This work aims at presenting a method for processing thermofilms and describing the possibilities of its application under real conditions.

Materials and Methods. A method for processing thermographic films was described. It provided detecting temperature anomalies using only information from the camera. The results of its application on the elements of existing metal bridge spans are presented.

Results. It is shown that there are temperature anomalies for existing defects. This means that the defects continue to develop, which was confirmed by subsequent observations of their condition. In addition, a case of temperature anomaly in the defect-free external region was identified. This might be a sign of an incipient defect that could not be diagnosed by other methods. If the presence of this defect is confirmed during repeated examinations, it will be possible to diagnose hidden defects that have not yet come to the surface, and/or detect potentially collapsing places.

Discussion and Conclusions. The IR thermography performance as a method of non-contact non-destructive testing is shown, as well as its operability on real objects under random load.
Study of the effect of cutting modes on output parameters under high-speed steel turn-milling
Authors: Matlygin D. A. , Savilov A. V. , Pyatykh A. S. , Timofeev S. A.
Published: July 2022

Introduction. The article elucidates increasing the efficiency of turn-milling of powdered metal high-speed steel products. Turn-milling can be used as an alternative to the traditional turning method. The article describes advantages of the turn-milling method. A review of studies devoted to improving the surface quality of parts when turning by milling is given. The work aims at determining the effect of cutting modes on the surface roughness by the orthogonal turning method through milling powdered high-speed steel with a monolithic cutter.

Materials and Methods. Statistical analysis methods based on the creation of a mathematical model for predicting microgeometric deviations of the treated surface were used. An experimental research method was applied to verify the adequacy of the mathematical model. The experiment was planned according to the non-composite design proposed by Box and Behnken. The experiment was carried out on a turning machining center with a driving tool. Powdered highspeed steel BÖHLER S390 MICROCLEAN was used as sample material for the experiment. A monolithic carbide milling cutter served as a cutting tool. During the experiment, the cutting speed, milling width, and feed per tooth varied. The roughness of the treated surface was measured by a contact profilometer.

Results. A mathematical model of the formation of surface roughness depending on the processing modes was developed. During the experiments, the effect of cutting speed, tool feed, and radial cutting depth on the roughness of the treated surface was determined. It was established that the dependence of roughness on feed had a linear character over the entire investigated range of cutting modes. In turn, the dependence of roughness on the cutting speed and cutting width had a parabolic character. The results obtained allowed us to achieve the roughness of the treated surface Ra = 1.85 without reducing the processing performance. Discussion and

Conclusions. The developed mathematical model reflects the impact of cutting modes on the surface roughness when turning high-speed steel with a monolithic cutter. The results of the conducted research can be used to determine the optimal cutting modes that provide a given surface quality in the manufacture of real parts under the production conditions. It is recommended to continue the research with the control of additional output parameters, such as temperature and vibration. Reducing the effect of regenerative self-oscillations on the roughness of the treated surface can be reached through assigning the cutting modes based on the results of a modal analysis of the process system.
Peranan Mediasi IPM Pada Pengaruh Pertumbuhan Ekonomi Terhadap Tingkat Kemiskinan Kabupaten Jember Tahun 2010 - 2020
Authors: AROFAH FIRDANIA MAY , Sishadiyati Sishadiyati
Published: July 2022

This quantitative research is based on the problem of high poverty in Jember Regency, which is inversely proportional to the relatively stable rate of economic growth and HDI value, which is constantly increase, indicating assuming that ideal conditions not actually happen. The goal of this research is to determine the effect of economic growth on poverty levels in Jember Regency by using HDI variable as a moderating variable. This research used secondary data obtained from the official website BPS of Indonesian, East Java Province and Jember Regency from 2010 to 2020. The data is analyzed using the path analysis method and followed by Sobel test, which is used to determine indirect effect of the intervening variable. This research found that economic growth has no significant effect on HDI and poverty rates, then HDI has a significant effect on poverty rates and can used as intervening variable.
EFEKTIVITAS MEDIA WORDWALL UNTUK MENINGKATKAN HASIL BELAJAR EKONOMI SISWA MAN 1 LAMONGAN
Authors: Minarta Sakinata Maulidina , Pamungkas Heni Purwa
Published: July 2022

This study aims to analyse the effect of Wordwall learning media in increase economics learning outcomes for students in class XI IPS 1 MAN 1 Lamongan. The subjects of this study were 24 students of class XI IPS 1 MAN 1 Lamongan. This research was an experimental study with one-group pre-test post-test design.The analytical technique used reliability test, normality test, homogenity test, N-Gain test, and also Wilcoxon test. Based on the results of the Wilcoxon test analysis on the pre-test and post-test data of the experimental group showed a sig (2-tailed) value of 0.001 < 0, 05, which means that there is a significant difference between before and after treatment. It can be concluded that Wordwall learning media (X) has a significant effect on student learning outcomes of XI IPS 1MAN 1 Lamongan (Y).
ANÁLISE DAS DECISÕES JUDICIAIS DO SUPERIOR TRIBUNAL DE JUSTIÇA ACERCA DO DIREITO SUCESSÓRIO DO CÔNJUGE/COMPANHEIRO CASADO/CONVIVENTE PELO REGIME DA COMUNHÃO PARCIAL DE BENS EM CONCORRÊNCIA COM OS DESCENDENTES DO DE CUJUS NA SUCESSÃO LEGÍTIMA
Authors: Orselli Helena , Rampelotti Silva Evaristo Kheila Cristine
Published: July 2022

Analisaram-se os argumentos dos Ministros do Superior Tribunal de Justiça acerca concorrência sucessória do cônjuge/companheiro supérstite casado/convivente pelo regime da comunhão parcial de bens com os descendentes do de cujus. em cinco Recursos Especiais julgados desde a entrada em vigor do Código Civil de 2002 até 1 de agosto de 2019. A metodologia fundou-se no método indutivo, e nas técnicas de revisão bibliográfica, fichamento, referente e análise descritiva e comparativa. Cinge-se a controvérsia à interpretação dada ao inciso I do artigo 1.829 do Código Civil, que vincula a concorrência sucessória do cônjuge/companheiro casado/convivente pelo regime da comunhão parcial de bens à existência de bens particulares deixados pelo de cujus sem estabelecer expressamente sobre que parte da herança o cônjuge herdaria. O texto legal admite correntes interpretativas diversas devido a sua obscuridade. Das decisões do Superior Tribunal de Justiça analisadas, nos REsp. 1.117.563-SP (2009), e REsp. 1.377.084-MG (2013), adotou-se a posição que confere ao cônjuge/companheiro direito de concorrência sucessória sobre os bens comuns que compõem a herança do de cujus. Nos REsp. 974.241-DF (2011) e REsp. 1.368.123-SP (2015), julgou-se a favor de conceder o direito sucessório do cônjuge somente em relação aos bens particulares do autor da herança. Em 2019, nos REsp 1.617.650-RS e REsp 1.617.501-RS, a Terceira Turma decidiu unanimemente que o companheiro, convivente sob o regime da comunhão parcial de bens, herda apenas do patrimônio particular do de cujus. Após longo debate acerca do assunto entre os Ministros das Terceira e Quarta Turma, houve uma pacificação acerca do tema.
A TECNOLOGIA APLICADA AO SETOR BANCÁRIO COMO INSTRUMENTO DE DIMINUIÇÃO DA VERTICALIZAÇÃO: A DEFESA DA CONCORRÊNCIA ENTRE AS OPERADORAS DE CARTÃO DE CRÉDITO
Authors: Oliveira Bruno , Arakaki Allan
Published: July 2022

O presente artigo aborda como a incorporação de novas tecnologias no setor bancário, como o mobile payments e as fintechs, auxiliou na diminuição da verticalização do segmento bancário, fomentando a concorrência entre operadoras de cartão de crédito. Para tanto, utiliza-se da pesquisa bibliográfica, consistente na doutrina jurídica, em matérias jornalísticas e em relatórios oficiais, bem como é aplicado o método dedutivo. Aborda-se, de início, a intensa verticalização do mercado bancário, consistente na alta concentração de elos de uma cadeia negocial em torno de um grupo restrito, prejudicando os princípios da livre iniciativa e livre concorrência. Após, adentra-se à concorrência entre as operadoras de cartão de crédito e as máquinas de cartão de crédito. Por fim, conclui-se que o mobile payments e as fintechs, inovações decorrentes da incorporação tecnológica ao sistema de pagamento, podem melhorar a competitividade do setor, diminuindo o grau de verticalização do mercado bancário e tornando este mais eficiente.
Formulasi dan Evaluasi Gel Nanopartikel Perak
Authors: Edityaningrum Citra Ariani , Oktafiani Artika Tri , Widiyastuti Lina , Arimurni Dewa Ayu
Published: July 2022

Nanopartikel perak diketahui dapat menembus membran sel bakteri penyebab jerawat dan menyebabkan kerusakan struktural yang berakibat pada kematian sel bakteri. Nanopartikel perak perlu diformulasikan dalam bentuk gel agar memudahkan dalam penggunaannya. Penelitian ini dilakukan untuk mensintesis nanopartikel perak dan memformulasikannya dalam bentuk gel. Sintesis nanopartikel perak dilakukan menggunakan metode reduksi kimia dengan reduktor natrium sitrat dan penstabil gelatin. Nanopartikel perak kemudian diformulasikan dalam sediaan gel dengan variasi konsentrasi HPMC 7%, 10%, dan 15%. Hasil karakterisasi menunjukkan telah terbentuk nanopartikel perak berdasarkan panjang gelombang maksimal yang terbentuk yaitu 430,2 nm, absorbansi 0,297, ukuran partikel 157,73±15,03 nm, indeks polidispersitas 0,328±0,032, dan morfologi bulat. Berdasarkan hasil analisis, dapat disimpulkan bahwa formula 3 dengan konsentrasi HPMC 15% merupakan formula terbaik dengan sifat fisik berupa nilai viskositas 3931,75 ± 92,383 cps, diameter sebar 6,41 ± 0,06 cm dan daya sebar 22,78 ± 0,221 g.cm/detik, daya lekat 59,43 ± 1,158 detik, serta nilai pH 5,81 ± 0,04.
Penambatan Molekuler Senyawa Bioaktif Daun Wungu (Graptophyllum Pictum (L) Griff) sebagai Inhibitor Tirosinase
Authors: Aziz Abdul , Andrianto Dimas , Safithri Mega
Published: July 2022

Melasma is a skin disorder characterized by hyperpigmentation of the skin in areas exposed to sunlight and is included in the dominant skin disorder category in several countries. Meanwhile, data from the Food and Drug Administration shows that cosmetic products have progressed from 0.01% to 57.4% in terms of registered products over the last six years. Currently, melasma treatment and cosmetic applications as a whitening agent were carried out by regulating tyrosinase activity through the use of compounds such as kojic acid which poses a health risk. Therefore, it was necessary to have other alternatives that can regulate tyrosinase activity without harming health. This study aimed to determine inhibitory effects of wungu leaf (Graptophyllum pictum (L) Griff) bioactive component as an agent to inhibit tyrosinase activity through a molecular docking approach. A total of 28 wungu leaves bioactive components as a result of the analysis of Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography-Flame Ionization Detector (GC-FID) were tested for their inhibitory effects on tyrosinase activity. Linolenic acid and phytol were ligands that have the best inhibition on tyrosinase enzyme activity with affinity energies of -5.8 kcal/mol and -5.4 kcal/mol, respectively, and inhibition constants of 55.718 M and 109.489 M.
Innovative Services During Pandemic at UIN Sunan Kalijaga Yogyakarta Library: A ServQual Analysis
Authors: Marwiyah  , Labibah  , Khotimah Khusnul , Astuti Sri , Prabowo Thoriq Tri
Published: July 2022

Academic library contributes much to the realization of the three pillars of higher education, which are education, research, and social services. During pandemic, university library has to keep contributing to the development of education even when learning-teaching activities are virtually conducted. This research is aimed at identifying sorts of service developed by UIN Sunan Kalijaga Yogyakarta library during the pandemic and at exploring the users’ responses to them by using ServQual approach to evaluate three aspects of innovative services, namely the services being developed, the service supporting facility, and the human resources. This research uses a qualitative method. The data were collected through interviews with 17 qualified informants and documentation. The study showed that the library has made some innovative services to satisfy the users’ needs, particularly the students who were doing their last assignments. The users have benefited much from the innovative services and declared their satisfaction. In term of facility, the library is completed with facilities and infrastructure that are in line with the health protocols. The library also used social media, like WhatsApp and Instagram, to support its services. In addition, the librarians have significantly helped the users access the services.
Abstract Data Interpolation in Library OPAC: from the Perspective of Information Dissemination
Authors: Kristyanto Dian
Published: July 2022

OPAC libraries basically have provided complete metadata with various data fields that can be used to contain more detailed collection information. This paper will analyze the potential for additional data collections, especially collection abstractions from the point of view of information needs and information dissemination. The study used a literature review analysis by referring to several sources of information such as scientific articles from electronic journals or other online sources as well as books relevant to this study. The data was obtained by observing the OPAC of online-based libraries from several educational institutions. The results of the study showed that the metadata pattern built by the library is still limited to a brief description of the collection so that the benefits of the information are not necessarily obtained by the user. The addition of abstract data to the OPAC, from the point of view of information dissemination is very necessary because the users need more detailed information. Libraries can add abstract data by choosing one of the methods in the summary process, namely abstraction and extraction.
The Future Direction of Pesantren's Research: A Bibliometric Analysis
Authors: Mustofa Mahmud Yunus , Mas'ud Abdurrahman , Elizabeth Misbah Zulfa
Published: July 2022

Academics have not quantified the quantity and quality of research conducted on pesantren (Islamic boarding school), particularly concerning the development of digital technology. Indeed, the current pesantren trend has accelerated as a response to the development of online media. This article will analyze emerging research trends, mentor academics involved in pesantren’s research, and direct researchers. Additionally, this article discusses the most influential authors and journals in the area. The research aims to evaluate pesantren's research trends indexed in Scopus using bibliometric analysis software Publish or Perish and VOS Viewer. The study discovered that pesantren's research has shifted during the last decade. According to the data, scholars continue to study pesantren's research themes infrequently, as indicated by the indexation of only 61 publications by Scopus. The majority of researchers use a conventional approach to pesantren. As such, it is critical to conduct future research on the relationship between pesantren and the advancement of digital technology. Specifically, in the form of Kiai (teacher) or santri-based learning (student-based learning) models and the process of pesantren adaptation, as indicated by the establishment of numerous pesantren media platforms as centers for religious knowledge production and dissemination. Thus, pesantren will keep being the source of religious knowledge by adapting to tradition and technology.
Checklist Method in Evaluation of Collection Development
Authors: Hafsera Dian , Rahmi Lailatur , Husna Zalmi Fadhila Nurul , Harahap Ilham Kamil
Published: July 2022

This study aims to identify and analyze the availability of a collection of compulsory subject teaching materials in the Library Science study program at UIN Imam Bonjol Padang. This quantitative research uses the checklist method. The research data was obtained from the RPKS/Syllabus reading list for compulsory subjects and interviews. The results of this study include an explanation of the collection based on the type of subject of the collection, the language of the collection, and the percentage of the availability of the collection to the needs of Lecturers at the Faculty of Adab and Humanities UIN Imam Bonjol. The results of this study indicate that the types of collections used in the 2018/2021 Academic Year are 75% of English Language Textbooks and Special Guidelines related to Library Science, especially in Processing Collections both Internationally and from the National Library. Data analysis shows that the number of reading lists of 20 compulsory subjects in the study program is 172 titles, with an average of 1-2 copies originating from purchases and gifts if more than 10 copies. Document data analysis resulted in the number of available reading lists in 20 courses, with the number of available collections being 37.2% and not available as much as 62.7%.
Healing time of experimentally induced distal limb wounds in horses is not reduced by local injection of equine-origin liquid amnion allograft
Authors: Duddy Hugh R. , Schoonover Mike J. , Williams Megan R. , Rudra Pratyaydipta
Published: July 2022

OBJECTIVE

To assess the efficacy of an equine-origin liquid amnion allograft (ELAA) derived from both amniotic fluid and amniotic membrane on the healing time of experimentally induced distal limb wounds in horses.

ANIMALS

8 adult horses.

PROCEDURES

On day 0, horses were anesthetized and a 2.5 X 2.5-cm, full-thickness skin wound was created on the dorsal aspect of each metacarpus and bandaged. On day 9, wound margins were injected with ELAA (treatment) or 0.9% NaCl (control). Bandages were changed at specific intervals through day 91 and, on each occasion, wounds were photographed to allow calculation of wound area. Exuberant granulation tissue was resected, if present. Wounds were deemed healed when completely epithelialized. Mean wound area was compared between groups throughout the study period.

RESULTS

Only 1 wound (control) remained unhealed at day 91. No difference was found between the treatment and control groups in either wound area over time (P = 1.0) or time for wounds to reduce in size by 95% (P = .2) Exuberant granulation tissue required resection twice (1 control wound and 1 treatment wound).

CLINICAL RELEVANCE

In this model, a single treatment with ELAA administered locally by SC injection did not accelerate distal limb wound healing in horses. However, it is possible that naturally occurring, chronic, or nonhealing wounds would respond differently.
Ageing of rural populations in Eastern Poland
Authors: Kiniorska Iwona , Pytel Sławomir
Published: July 2022

A demographic view of the ageing process of a population provides an assessmentof the degree of development of this phenomenon and its dynamics at a given time in a given area, such as an administrative unit, a country or other territory. In this study, the main research aim was to assess the demographic situation of rural areas in Eastern Poland in the context of an ageing population. Changes in both the number of people and the demographic structure of the population living in the region were analysed. The time period of the research covered the years 2008-2020. Statistical data used in the study were derived from the Local Data Bank of Statistics Poland. The assessment of the regional specificity of the processes of demographic changes in rural areas was based on the study of the relationships in the analyzed parameters, with the use of statistical measures defining the range of variability of the examined characteristics. In order to achieve the main aim of the study, a typology of the areas with a disturbed age structure was developed. Four groups of rural areas have been identified (labelled from A to D) which are characterised by varying degrees of advancement of the examined problem in 2020.
Spatial Trends of Grassland Changes Based on Hungarian Local Studies After 1990 with a Macro-Regional Perspective
Authors: Kovács Krisztina Filepné , Iváncsics Vera , Boromisza Zsombor , Valánszki István
Published: July 2022

Grasslands contribute to the ecological diversity of our cultural landscapes. In the last centuries, the most important trend was a constant loss of this valuable asset due to urbanization and the intensification of cultivation. Studies focusing on grasslands are not so abundant, and especially analyses on the spatial trends of grasslands in Eastern-Central Europe are scarce. Focusing on Hungarian local studies, we analyze our results from a macro-regional perspective, with a draft study of the V4 countries (Slovakia, the Czech Republic, Hungary and Poland). The authors employed GIS and statistical methods to analyze data to explore trends of changes of grasslands in V4 countries, Hungary, and in three micro-regions of different landscape character. These include an open landscape, partly intensively cultivated (micro-region of Csorna), and two more diverse landscapes with different proportion of forests (micro-regions of Gönc and Veszprém). Our results show that very complex, sometimes opposite processes influence the area of grasslands. In spite of the fact that an increase in the area of grasslands is witnessed at both the national and the international level in absolute values, recently, unfavorable processes have started, and there are certain landscapes where grasslands are threatened especially natural grassland by forestation and grasslands where soil conditions are suitable for crop production. Our results showed that despite the different landscape conditions, the majority of grassland has been turned into arable land and into shrubs and forest area. The loss of pastures due to urban sprawl is a dominant process just around the built-up area of city of Veszprém in the most urbanized study area.
Analysing the shielding effectiveness of rectangular enclosure by determining aperture dimensions with particle swarm optimization
Authors: Güler Sunay
Published: July 2022

Electromagnetic shielding enclosure is used to protect electronic circuits against external EMI. Aperture on the enclosure, which is necessary for various reasons such as mounting connector, ventilation attenuates shielding effectiveness (SE) of the enclosure. Enlarging enclosure dimensions makes SE get better. Yet, they canot be designed so large due to weight and dimension considerations for EV. When the dimensions of the shielding enclosure remain fixed and the aperture is to have a particular area, it is essential to optimize aperture dimensions to increase SE. In this paper, an optimization methodology based on PSO is designed to obtain the optimal SE for a particular dimension range. The study also provides a comparative analysis between designed optimization methodology and the one based on genetic algorithm in the literature. Obtained SE results indicate that the optimization methodology establishes a very good agreement with the results in the literature. Moreover, it has faster convergence and higher calculation accuracy than GA and it utilizes a smaller number of parameters thanks to its simplicity. Finally, it is concluded that through designed optimization methodology in this study, SE of the enclosure can be raised by optimizing aperture dimensions when the dimensions of shielding enclosure remain fixed.
Nordic Concrete Research workshop: “Accelerated freeze-thaw testing of concrete”, Lyngby, 20th April 2022
Authors: Hasholt Marianne Tange , Frid Katja , Spörel Frank , Lahdensivu Jukka , Helsing Elisabeth , Müller Matthias , Faheem Abdul , Sleiman Sara Al Haj , Jacobsen Stefan
Published: July 2022

A one-day Nordic Concrete Research workshop on “Accelerated freeze-thaw testing of concrete” attracted approx. 30 participants. The workshop included presentations on various aspects, such as observed frost damage in the field and the importance of the temperature curve during testing as well as other interactions with the surroundings of the concrete. The workshop also included examples of recent research, which can improve our knowledge about the frost damage mechanism and therefore provide input to improving the standardised test methods. The present paper is a summary of the nine presentations and the discussion arising from the presentations.
Analysis of the Attitude of Hungarian HR Professionals to Artificial Intelligence
Authors: Karacsony Peter
Published: July 2022

Human resource (HR) management is one of an organisation’s most important core activities. As new technologies and software applications spread, it is important to recognise that human resource management must also mature and, to this end, must apply new technological guidelines. Artificial intelligence (AI) is one such promising technology trend that is likely to change the existing methods of HR management. This paper examines the attitudes that AI evokes among practicing HR professionals and assesses the potential for the practical application of these technologies. A survey, in the form of a questionnaire, was conducted among Hungarian HR managers, which allowed the collection of first-hand data. The survey was conducted in winter 2021 using the snowball method sampling procedure. The questionnaire mainly contained Likert-scale questions. The results of the research show that survey participants have mixed emotions about AI. The respondents largely agreed that the tools provided by AI are effective and their use helps HR management. The main limitation of the research is that it is limited to just one country, since the COVID-19 pandemic made it difficult to find and involve respondents in the research.
Digital Transformation (DT): An Overview of International Scientific Production in the Last Decade
Authors: Tutida Alessandra Yula , Rossetto Carlos Ricardo , Santos Ruan Carlos dos , Mazon Gisele
Published: July 2022

Purpose: To describe the state of the art of digital transformation research, providing an overview of some trends in international scientific articles and recommendations for future research.
Methodology/approach: Systematic Literature Review. To select the papers on Digital Transformation (DT) to be evaluated, we retrieved all articles from the Scopus and Wef of Science (WoS) databases. We used "Digital transformation" OR "Digital Transfor*."
Originality/Relevance: Companies have reaped the benefits of increased cost and productivity of technology, which has led to the emergence of new products and services based on technology and information systems. 
Key findings: This systematic literature review aims to help managers understand the phenomenon of DT, encourage them to think differently about it, and enable the development of interesting empirical studies in subsequent research.
The work aims to support managers in responding to the strategic challenges of DT.
Theoretical/methodological contributions: This paper aims to serve as a basis for further research in this area in order to broaden the scope of scientific discussions on the impact of TD. We provide an updated review on DT from a management perspective, synthesizing and integrating the current state of knowledge in a comprehensive and connective framework, highlighting aspects on Fashion Industry, Market orientation, digital transformation, Innovative Pedagogical Approaches, Digital Technology and Revenue Management.
The Resistive Switching Characteristics and Electrical Conduction Mechanisms of Memory Devices Based on Nanocomposite
Authors: Kim Ngoc Pham , Tu Uyen Doan Thi , Nhu Phuong Pham Le Quynh , Xuan Dat Mai Ngoc
Published: July 2022

The resistive switching memory device based on nanocomposites has become a potential candidate in the data storage field. Understanding resistive switching characteristics and electrical conduction mechanisms may support the appropriate way to fabricate and control the operation of a device. In this study, a capacitor-like structure using PVA-ZnO as an insulator layer was fabricated by a solution method. The crystalline structure, morphology, and absorption spectrum of ZnO nanoparticles were revealed respectively. The resistive switching effect was observed with the ON/OFF ratio of 0.5´102, high endurance, excellent retention and the electrical transport mechanisms were followed by the SCLC and Ohmic’s law in the low resistance state and Flower- Nordheim tunneling in the high resistance state. The resistive switching mechanism was contributed by the oxygen vacancies in ZnO nanoparticles and the oxygen ions in the bottom electrode.
Influences of ZnO Nanorod Arrays on Photocatalytic Activity of n-ZnO Nanorods/p-Si Heterostructure
Authors: Dinh Lam Nguyen
Published: July 2022

Zinc oxide is known as an excellent material for biosensors, solar cells, semiconductors and photocatalysts. In this work, n-ZnO nanorods/p-Si heterostructures were successfully fabricated by a hydrothermal method at different baking temperatures. The n-ZnO nanorods/p-Si heterostructures show good photocatalytic ability at high baking temperature. The concentration of Rhodamine B can be decreased up to 97% after 150 min treated by the n-ZnO nanorods/p-Si heterostructures grown at 80 oC. This result indicates that the n-ZnO nanorods/p-Si heterostructures are capable of being used in the decomposition of organic compounds.
Synthesis and Waterproofness Improvement of K3AlF6:Mn4+ Phosphor for Warm White Light-emitting Diodes
Authors: Dat Le Quoc , Tung Duong Thanh , Hung Nguyen Duy
Published: July 2022

In this study, we synthesized K3AlF6:Mn4+ phosphor by co-precipitation method. The crystal structure and photoluminescence properties were investigated. By surface modification of K3AlF6:Mn4+ using K3AlF6, the moisture resistance performances of the phosphor can be significantly improved. It was found that the luminescence performance of K3AlF6:Mn4+@K3AlF6, which was dispersed in water for 2 h, is unchanged but the uncoated  sample reduces dramatically. White light emitting diodes (WLEDs) based on the phosphor combined with commercial YAG:Ce3+ coated on a blue LED showed significantly improved of performance with color correlated temperature (CCT) from 5307 K down to 3528 K and color rendering index (CRI) from 64 up to 87. The results exhibit the potential for the application of K3AlF6:Mn4+@K3AlF6 as a red phosphor in warm WLEDs.
Facile Hydrothermal Method for Fabrication Seedless ZnO Nanorod/GO Composite on PCB
Authors: Sang Nguyen Xuan , Mai Nguyen Hoang , Thi Thuy Pham , Tuan Nguyen Tri , Tuan Pham Van , Cuong Hoang Van
Published: July 2022

Herein we report a simple method to grow ZnO nanorod/Graphene oxide (GO) array without the initial seed layer on a printed circuit board (PCB) as the substrate based on Galvanic effect. The hydrothermal growing conditions such as temperature and time were investigated by X-ray diffractometry (XRD), Raman scattering, as well as Scanning Electron Microscopy (SEM). It shown that as-prepare ZnO nanorod was grown well-vertically on the substrate. Furthermore, we investigated the photocatalytic activity of synthesized samples which showed the enhanced photodegradation ability in the composite sample.
Effective Couplings between Two Photons and Axion in the 3-3-1 Model
Authors: Ngoc Long Hoang , Van Vien Vo , Hoa Binh Vu
Published: July 2022

The one-loop contribution axion-photon-photon coupling is presented in the framework of the 3-3-1 model, in which the loop diagrams are finite. The decay of axion into two photons is demonstrated. This study shows that it is easy to fulfill dark matter candidate conditions for the axion in the model.
Linear and Nonlinear Magneto-optical Absorption Coefficients and Refractive Index Changes in Wse2 Monolayer
Authors: Van Tung Luong , Quang Bau Nguyen , Ngoc Bich Tran , Tuan Vinh Pham , Vinh Phuc Huynh
Published: July 2022

This work studies the linear, the third-order nonlinear, and the total optical absorption coefficients (OACs) and the refractive index changes (RICs) caused by both intra- and inter-band transitions in the WSe2 monolayer. The expression for the OACs and RICs in the presence of a magnetic field as well as the Zeeman and electric fields are found by using the compact density matrix approach. The results show that the spin states strongly affect the OACs and RICs, which display the violet-shift behavior with the increase of the magnetic field. The Zeeman fields do not affect the peak positions but slightly reduce peak intensities. The OACs and RICs due to intra-band transition display only one peak in the THz range, while the inter-band spectra show a series of peaks in the near-infrared optical range, making monolayer WSe2 be a promising candidate for novel optoelectronic applications.
Effect of Eu Doping on Structural, Optical and Magnetic Properties of BiFeO3 Materials
Authors: Viet Thang Dao , Manh Hung Nguyen , Phuong Thao Nguyen , Cao Khang Nguyen , Thi Mai Oanh Le , Thi Cam Linh Ngo , Dinh Tu Bui
Published: July 2022

Bi1-xEuxFeO3 (BEFO) (x = 0.00 ÷ 0.10) materials were prepared by sol-gel method. The crystal structural, Raman scattering, magnetic and optical properties of BEFO were investigated by X-ray diffraction (XRD), Raman scattering spectroscopy, magnetic hysteresis (M-H) loops and fluorescence spectroscopy (FL), respectively. Obtained results of the characterization showed that Eu-doping affected structural, optical and magnetic properties of BFO materials. All samples were crystallized in the rhombohedral structure with R3C space group with crystal lattice parameters of a = 5.585 Å, c = 13.832 Å and the average crystal size of LXRD = 581 Å for BFO materials whereas the a, c and LXRD of Eu-doped samples decrease with the increasing of Eu3+ concentration. The analysis result of Raman scattering spectroscopy showed that the position of the characteristic peak for Bi-O covalent bonds shifts toward higher frequency when Eu3+ concentration increases, confirming the dopping substitution of Eu3+ ions into Bi-sites. Fluorescence spectra showed the enhancement of characteristic emission peaks with the increase of Eu concentration. All samples exhibited weak ferromagnetic behaviour with saturation magnetization of Ms = 0.006 emu/g and remnant magnetization of Mr = 0.004 emu/g for BFO materials. The value of Ms and Mr of Eu-doped BFO increases compared to those of undoped-BFO. The origin of ferromagnetism and fluorescence improvement has been discussed.
Preparation of CuO Nanorods by Thermal Oxidation in Ozone Ambient
Authors: Ha Tran Thi , Thanh Cong Bach , Hai Pham Nguyen , Hoang Nguyen , Chinh Ho Van , Huong Bui Thu , Linh Nguyen Thuy , Son Bui Truong , Quynh Hoa Tran Thi , Nguyen Viet Tuyen
Published: July 2022

CuO nanorods were prepared by thermal oxidation method in ozone ambient. The effect of annealing temprature in the range from 400 to 600 oC on morphology and structure of nanorods was studied thouroughly by scanning electron microscopy (SEM) and X-ray diffraction, combining with energy dispersive spectroscopy (EDS) and Raman spectroscopy. The results showed that annealing temprature strongly affected the structure and morphology of the produced CuO nanorods. The most uniform nanorods with highest crystal quality were obtained when annealing temperature is from 450 to 500 °C and annealing time was 2 h as suggested by SEM images together with Raman results.
Synthesis and Characterization of Hierarchical CeO2 Spherical Nanoparticles for Photocatalytic Degradation of Methylene Blue
Authors: Huu Trinh Le , Duc Cuong Nguyen , Dang Trung Do , Van Hieu Nguyen
Published: July 2022

: In this study, hierarchical CeO2 spherical nanoparticles were fabricated by the polyol method using Ceri (III) acetate hydroxide, sodium hydroxide, and triethylene glycol as precursors. The product was characterized by XRD, SEM, and TEM. The results show that the cerium oxide spherical nanoparticles built from primary nanoparticles with the average size of ~5 nm, exhibited dispersion and uniform size and shapes with their average particle diameter of ~50 nm in size. With such a good morphology, CeO2 material possessed good catalytic activity for the decomposition of methylene blue (MB), in which the material was synthesized at a hydrothermal temperature of 80 oC (CeO2-80) for the best MB decomposition performance.
Ferromagnetic-antiferromagnetic Competition in Diluted Magnetic Semiconductors
Authors: Huu Nha Nguyen , Van Nham Phan
Published: July 2022

The signature of the magnetic competition in a nearly filled impurity band diluted magnetic semiconductors is addressed. In the formalism of the Kondo lattice model, self-consistent equations determining the Green function of the itinerant carrier in the system are evaluated by use of the dynamical mean-field theory. An analytical solution of the static spin susceptibility of the itinerant carrier to specify the magnetic instability is then established. Once the impurity band is nearly filled, one finds the antiferromagnetic instability against the ferromagnetic state. Phase diagrams of the magnetic structures in the diluted magnetic semiconductor were also discussed.
To Develop Piezoelectric based Acoustic Microfluidic Mixer
Authors: Tharun Kumar Reddy Pelleti
Published: July 2022

The main of this research is to solve the problems of the mixing of fluids in microchannels. The aim is to improve the mixing efficiency of the microchannel by employing the piezoelectric actuator. The objectives of the project are to, producing ZnO (Zinc Oxide) thin films, preparing the microchannel with desired dimensions and examining the mixing efficiency of the microchannel by employing the piezoelectric actuator. The ZnO nanoparticles were produced by the coprecipitation method, and the purity and phase were checked by using the XRD method, the ZnO thin films were produced by the Ultrasonic Spray pyrolysis, the thickness of the thin films was determined by using the Eddy current method, the mixing efficiency was measured by powering the piezoelectric actuator by AC source. The size of the nanoparticles is 53.88 nm, The thickness of the ZnO-coated copper thin films is 102 µm, the mixing efficiency can be increased up to 93.47% with the help of an active source of energy Piezoelectric actuator. The mixing efficiency is further increased by increasing the length of the microchannel, increasing the cross-sectional area of the microchannel, in the maximum voltage kept at 5 V because of the limitation of the piezoelectric actuator.