bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 through 8 from A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells
Authors: Hölzel Michael , Landsberg Jennifer , Glodde Nicole , Bald Tobias , Rogava Meri , Riesenberg Stefanie , Becker Albert , Jönsson Göran , Tüting Thomas
Published: March 2023

Supplementary Figure 1. Full GSEA enrichment plots. Related to main figure 3. Supplementary Figure 2. Transcription factor framework of pigmented versus amelanotic MPNST-like BrafV600E-Cdk4R24C melanomas. Related to main figure 3. Supplementary Figure 3. Overlap of gene signatures. Related to main figure 3. Supplementary Figure 4. Heatmap of BCMPNST-like signature z-score expression in human TCGA melanomas. Related to main figure 4A. Supplementary Figure 5. Melanoma-specific refinement of the immune cell subset signatures (ICSS). Related to main figure 5. Supplementary Figure 6. Immune cell subset signature (ICSS) z-scores in human TCGA melanoma samples. Related to main figure 5. Supplementary Figure 7. Mast cell infiltration in human MPNST-like melanomas. Related to main figure 5. Supplementary Figure 8. GSEA for mast cell and mast cell chemotaxis gene signature for comparison of MPNST-like and pigmented BrafV600E-Cdk4R24C mouse melanomas.
Table S6 from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: March 2023

Genes significantly induced in Be(2)-C or IMR5-75 upon treatment with DAC, EPZ-6438 or a combination of both drugs (adjusted p-value<0.05, sorted by log2 fold change)
Supplementary Table S1 from Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals
Authors: Hofmann Jonathan N. , Birmann Brenda M. , Teras Lauren R. , Pfeiffer Ruth M. , Wang Ye , Albanes Demetrius , Baris Dalsu , Colditz Graham A. , De Roos Anneclaire J. , Giles Graham G. , Hosgood H. Dean , Lan Qing , Landgren Ola , Liao Linda M. , Rothman Nathaniel , Weinstein Stephanie J. , Pollak Michael N. , Neuhouser Marian L. , Purdue Mark P.
Published: March 2023

Determinants of circulating levels of total adiponectin (µg/mL) among pooled controls.
Supplemenatary Methods and References from Low Levels of Circulating Adiponectin Are Associated with Multiple Myeloma Risk in Overweight and Obese Individuals
Authors: Hofmann Jonathan N. , Birmann Brenda M. , Teras Lauren R. , Pfeiffer Ruth M. , Wang Ye , Albanes Demetrius , Baris Dalsu , Colditz Graham A. , De Roos Anneclaire J. , Giles Graham G. , Hosgood H. Dean , Lan Qing , Landgren Ola , Liao Linda M. , Rothman Nathaniel , Weinstein Stephanie J. , Pollak Michael N. , Neuhouser Marian L. , Purdue Mark P.
Published: March 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figure Legends from Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Authors: Henrich Kai-Oliver , Bender Sebastian , Saadati Maral , Dreidax Daniel , Gartlgruber Moritz , Shao Chunxuan , Herrmann Carl , Wiesenfarth Manuel , Parzonka Martha , Wehrmann Lea , Fischer Matthias , Duffy David J. , Bell Emma , Torkov Alica , Schmezer Peter , Plass Christoph , Höfer Thomas , Benner Axel , Pfister Stefan M. , Westermann Frank
Published: March 2023

Legends for Supplementary Figures S1-S8.
Supplementary Figure S8 from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: March 2023

Effects of SK-216 on the phosphorylation of ERK1/2 and AKT
Supplemental Figure 3 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

The effect of polyamines on intracellular herbacetin concentration. The effect of polyamines on the intracellular herbacetin level was determined using HCT116 colon cancer cells. Cells were treated with herbacetin and putrescine, spermidine or spermine for 5 h in medium supplemented with 10% FBS and intracellular herbacetin was extracted and analyzed by using HPLC. All data are represented as means {plus minus} S.D. of triplicate values from 3 independent experiments.
Supplemental Figure 2 from Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity
Authors: Kim Dong Joon , Roh Eunmiri , Lee Mee-Hyun , Oi Naomi , Lim Do Young , Kim Myoung Ok , Cho Yong-Yeon , Pugliese Angelo , Shim Jung-Hyun , Chen Hanyong , Cho Eun Jin , Kim Jong-Eun , Kang Sun Chul , Paul Souren , Kang Hee Eun , Jung Ji Won , Lee Sung-Young , Kim Sung-Hyun , Reddy Kanamata , Yeom Young Il , Bode Ann M. , Dong Zigang
Published: March 2023

Effect of herbacetin on activity of various kinases. Herbacetin has no effect on (A) CHK1, (B) EGFR, (C) GSK3beta, (D) JNK1, (E) JNK2, (F) ERK1, (G) ERK2, (H) MEK1, (I) AKT1, (J) AKT2, (K) RSK2, (L) p38 or (M) PI3-K kinase activity or on (N) AdoMetDC activity. The effect of herbacetin on kinase or enzyme activity was determined by using an in vitro kinase or enzyme assay. All data are represented as mean values {plus minus} S.D. of values from duplicates experiments.
Supplementary Figure S4 from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: March 2023

Effects of SK-216, bevacizumab, and AZD4547 on intrapleural tumors and pleural effusions in SCID mice inoculated with MPM cells
Supplementary Table S4 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: March 2023

Association of Ezh2 expression with clinical parameters in RCC patients.
Supplementary Figure Legends from Inhibition of PAI-1 Limits Tumor Angiogenesis Regardless of Angiogenic Stimuli in Malignant Pleural Mesothelioma
Authors: Takayama Yusuke , Hattori Noboru , Hamada Hironobu , Masuda Takeshi , Omori Keitaro , Akita Shin , Iwamoto Hiroshi , Fujitaka Kazunori , Kohno Nobuoki
Published: March 2023

Legends for Supplementary Figures S1-S8
Supplementary Table S2 from Long Noncoding RNA MALAT1 Promotes Aggressive Renal Cell Carcinoma through Ezh2 and Interacts with miR-205
Authors: Hirata Hiroshi , Hinoda Yuji , Shahryari Varahram , Deng Guoren , Nakajima Koichi , Tabatabai Z. Laura , Ishii Nobuhisa , Dahiya Rajvir
Published: March 2023

Primer sequence information.
Supplementary table 6 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: March 2023

Association between CHPT1 expression in breast cancer samples and clinicopathological data.
Supplementary Figure 5 from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: March 2023

Supplementary Figure 5. miR-892b directly suppresses multiple key components in the NF-kappaB cascade.
Supplementary table 4 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: March 2023

Changes of Cho-containing metabolites upon E2 stimulation
Supplementary Figure 4 from miR-892b Silencing Activates NF-κB and Promotes Aggressiveness in Breast Cancer
Authors: Jiang Lili , Yu Liang , Zhang Xin , Lei Fangyong , Wang Lan , Liu Xiangxia , Wu Shu , Zhu Jinrong , Wu Geyan , Cao Lixue , Liu Aibin , Song Libing , Li Jun
Published: March 2023

Supplementary Figure 4. Overexpression of miR-892b suppresses breast cancer progression in vitro.
Supplementary figure 1 from Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism
Authors: Jia Min , Andreassen Trygve , Jensen Lasse , Bathen Tone Frost , Sinha Indranil , Gao Hui , Zhao Chunyan , Haldosen Lars-Arne , Cao Yihai , Girnita Leonard , Moestue Siver Andreas , Dahlman-Wright Karin
Published: March 2023

Characterization of ERα cistromes for MCF7 and T47D cells
Supplementary Figure 2| Circulating Hematopoietic Cells do not contribute to tumor blood vessels. from Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte–Endothelial Recognition to Foster Tumor Immune Escape
Authors: Corey Daniel M. , Rinkevich Yuval , Weissman Irving L.
Published: March 2023

Flow cytometry plots from wild-type mice reconstituted with cyan-fluorescent-protein hematopoietic stem cells CFP-HSCs showing the absence of CFP-HSC derived cells in blood vessels. (a) Flow cytometry plots showing gating of B16 tumors after enzymatic digestion. (b) Within the high expressing CD31 and CD144 subset, we find no contribution from CFP-HSCs (lower panel). (c) In contrast, within the CD45+ CD31-VeCad- subset representing the hematopoietic component of the tumor stroma, progeny of CFP-HSCs are detected. (d) Histologic section of bone marrow showing full blood chimerism 3 months after transplant.
Supplementary Table 3 from Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Authors: Osman Abdullah A. , Neskey David M. , Katsonis Panagiotis , Patel Ameeta A. , Ward Alexandra M. , Hsu Teng-Kuei , Hicks Stephanie C. , McDonald Thomas O. , Ow Thomas J. , Alves Marcus Ortega , Pickering Curtis R. , Skinner Heath D. , Zhao Mei , Sturgis Eric M. , Kies Merrill S. , El-Naggar Adel , Perrone Federica , Licitra Lisa , Bossi Paolo , Kimmel Marek , Frederick Mitchell J. , Lichtarge Olivier , Myers Jeffrey N.
Published: March 2023

Supplementary Table 3: Cox proportional hazard regression afterward backward selection and adjusting for EA score for overall survival.
Supplementary Table 2 from Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Authors: Osman Abdullah A. , Neskey David M. , Katsonis Panagiotis , Patel Ameeta A. , Ward Alexandra M. , Hsu Teng-Kuei , Hicks Stephanie C. , McDonald Thomas O. , Ow Thomas J. , Alves Marcus Ortega , Pickering Curtis R. , Skinner Heath D. , Zhao Mei , Sturgis Eric M. , Kies Merrill S. , El-Naggar Adel , Perrone Federica , Licitra Lisa , Bossi Paolo , Kimmel Marek , Frederick Mitchell J. , Lichtarge Olivier , Myers Jeffrey N.
Published: March 2023

Supplementary Table 2: Univariate analysis of overall survival.
Supplementary Table 3 from Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis
Authors: Housseau Franck , Wu Shaoguang , Wick Elizabeth C. , Fan Hongni , Wu Xinqun , Llosa Nicolas J. , Smith Kellie N. , Tam Ada , Ganguly Sudipto , Wanyiri Jane W. , Iyadorai Thevambiga , Malik Ausama A. , Roslani April C. , Vadivelu Jamunarani S. , Van Meerbeke Sara , Huso David L. , Pardoll Drew M. , Sears Cynthia L.
Published: March 2023

Supplementary Table S3. Demographic and pathologic characteristics of the Malaysian CRC patients.
Supplementary Figure S8 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Expression of pooled CIS genes in Ba/F3 cells.
Supplementary Figure S6 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Expression of individual CIS genes are associated with survival of ALL patients.
Supplementary Figure S3 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Consensus clustering analysis of 4898 CIS genes in human AML and expression of CIS genes in high-risk and low-risk ALL patient subgroups.
Supplementary Figure S13 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

CRISPR/Cas9-mediated inhibition of USP32 reduces proliferation in vitro and prolongs survival in vivo.
Supplementary Figure S10 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Phosphorylation of STAT5 in Ba/F3 cells overexpressing CIS genes.
Supplementary Table 1 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: March 2023

The percentage of infiltrating immune cells in B16 tumor tissue
Supplementary Figure S2 from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: March 2023

In silico identification of miR-21 and the effect of miR-21 decoy gene.
Supplementary Figure S1 from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: March 2023

Variant filtering process for whole-exome sequencing.
Supplementary Figures 1 through 6 from Aspirin Suppresses the Acquisition of Chemoresistance in Breast Cancer by Disrupting an NFκB–IL6 Signaling Axis Responsible for the Generation of Cancer Stem Cells
Authors: Saha Shilpi , Mukherjee Shravanti , Khan Poulami , Kajal Kirti , Mazumdar Minakshi , Manna Argha , Mukherjee Sanhita , De Sunanda , Jana Debarshi , Sarkar Diptendra K. , Das Tanya
Published: March 2023

Supplementary Figure S1: Immunohistological images representing ER, PR and Her2 staining of primary tumor cells and schematic representation showing flow cytometric sorting. Supplementary Figure S2: FAC-based chemotherapy increases CSC pool in different breast cancer cells. Supplementary Figure S3: FAC-based chemotherapy generates aggressive CSC pool. Supplementary Figure S4: Therapy fails to induce CSC-markers in purified NSCCs of MCF-7 cells. Supplementary Figure S5: Therapy induces translocation of NFÃŽÂºB in nucleus of CSCs. Supplementary Figure S6: Aspirin treatment perturbs NFÃŽÂºB nuclear translocation in CSC-enriched spheres and chemo-sensitizes CSCs to genotoxic therapy.
CTL CD103+ on rE-cadh-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Authors: Boutet Marie , Gauthier Ludiane , Leclerc Marine , Gros Gwendoline , de Montpreville Vincent , Théret Nathalie , Donnadieu Emmanuel , Mami-Chouaib Fathia
Published: March 2023

CTL CD103+ on rE-cadh-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Supplementary Table 3 from An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo
Authors: Lohse Stefan , Meyer Saskia , Meulenbroek Laura A.P.M. , Jansen J.H. Marco , Nederend Maaike , Kretschmer Anna , Klausz Katja , Möginger Uwe , Derer Stefanie , Rösner Thies , Kellner Christian , Schewe Denis , Sondermann Peter , Tiwari Sanjay , Kolarich Daniel , Peipp Matthias , Leusen Jeanette H.W. , Valerius Thomas
Published: March 2023

Relative Quantitation of N-glycan structures.
Supplemental Fig.S2. from HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy
Authors: Liu Tongzheng , Fang Yuan , Zhang Haoxing , Deng Min , Gao Bowen , Niu Nifang , Yu Jia , Lee SeungBaek , Kim JungJin , Qin Bo , Xie Fang , Evans Debra , Wang Liewei , Lou Wenhui , Lou Zhenkun
Published: March 2023

Supplemental Fig.S2. HEATR1 regulates cancer cell response to chemotherapy and cell growth
Supplemental Fig.S1. from HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy
Authors: Liu Tongzheng , Fang Yuan , Zhang Haoxing , Deng Min , Gao Bowen , Niu Nifang , Yu Jia , Lee SeungBaek , Kim JungJin , Qin Bo , Xie Fang , Evans Debra , Wang Liewei , Lou Wenhui , Lou Zhenkun
Published: March 2023

Supplemental Fig.S1. HEATR1 regulates cancer cell response to chemotherapy
Supplementary Figure 2 from An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo
Authors: Lohse Stefan , Meyer Saskia , Meulenbroek Laura A.P.M. , Jansen J.H. Marco , Nederend Maaike , Kretschmer Anna , Klausz Katja , Möginger Uwe , Derer Stefanie , Rösner Thies , Kellner Christian , Schewe Denis , Sondermann Peter , Tiwari Sanjay , Kolarich Daniel , Peipp Matthias , Leusen Jeanette H.W. , Valerius Thomas
Published: March 2023

EGFR Expression on target cells were evaluated using 1 µg/ml cetuximab and FITC-labeled goat-anti human IgG antibody by indirect immunofluorescence and flow cytometry.
Supplemental Fig.S.5. from HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy
Authors: Liu Tongzheng , Fang Yuan , Zhang Haoxing , Deng Min , Gao Bowen , Niu Nifang , Yu Jia , Lee SeungBaek , Kim JungJin , Qin Bo , Xie Fang , Evans Debra , Wang Liewei , Lou Wenhui , Lou Zhenkun
Published: March 2023

Representative strong and weak staining of HEATR1 in pancreatic ductal adenocarcinoma.
Supplemental Fig.S.3 from HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy
Authors: Liu Tongzheng , Fang Yuan , Zhang Haoxing , Deng Min , Gao Bowen , Niu Nifang , Yu Jia , Lee SeungBaek , Kim JungJin , Qin Bo , Xie Fang , Evans Debra , Wang Liewei , Lou Wenhui , Lou Zhenkun
Published: March 2023

HEATR1 colocalized with Akt and regulates Akt phosphorylation independent of PDK1
Supplementary Tables S1-S4 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: March 2023

Supplementary Tables S1-S4. Comparison of miR-29s expression levels with clinic-pathological features in patients with primary gastric cancer (S1); miR-29s associated with disease-free survival of patients with GC in the training set (S2); Sequences of miR-29s, Ts-miRs, and catenin-ÃŽ' primers (S3); Immunohistochemistry reactions were quantitatively assessed using two methods (S4).
Supplemental Figure 4 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: March 2023

Hu14.18K322A and hu14.18-IL2 do not impact intrinsic cell sensitivity to radiation in vitro and radiation does not impact GD2 expression but GD2-expression is required for the cooperative in vivo interaction of radiation with hu14.18K322A or hu14.18-IL2.
Supplementary Table 1 from Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
Authors: Pathania Rajneesh , Ramachandran Sabarish , Mariappan Gurusamy , Thakur Priyanka , Shi Huidong , Choi Jeong-Hyeon , Manicassamy Santhakumar , Kolhe Ravindra , Prasad Puttur D. , Sharma Suash , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: March 2023

Supplementary table 1 will provide a complete list of genes that are differentially regulated genes in RNA-seq analysis for control and 5-AzaC+Butyrate treated CSCs
Supplementary Figure S3 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: March 2023

Supplementary Figure S3. Enforced expression of miR-29s in MGC803 and HGC27 cells.
Supplementary Figure S1 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: March 2023

Supplementary Figure S1. miR-29s expression analyses in GC cells.
Supplementary Methods and References from Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells
Authors: Mittal Deepak , Caramia Franco , Michiels Stefan , Joensuu Heikki , Kellokumpu-Lehtinen Pirkko-Liisa , Sotiriou Christos , Loi Sherene , Smyth Mark J.
Published: March 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary figure 3 from p73 and IGF1R Regulate Emergence of Aggressive Cancer Stem–like Features via miR-885-5p Control
Authors: Meier Claudia , Hardtstock Philip , Joost Sophie , Alla Vijay , Pützer Brigitte M.
Published: March 2023

Stable expression of miR-885-5p
Supplementary Table S2 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: March 2023

Results of promoter level Differential Expression Analysis by EdgeR.
Fig.S9 from Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer
Authors: Quemener Cathy , Baud Jessica , Boyé Kevin , Dubrac Alexandre , Billottet Clotilde , Soulet Fabienne , Darlot Florence , Dumartin Laurent , Sire Marie , Grepin Renaud , Daubon Thomas , Rayne Fabienne , Wodrich Harald , Couvelard Anne , Pineau Raphael , Schilling Martin , Castronovo Vincent , Sue Shih-Che , Clarke Kim , Lomri Abderrahim , Khatib Abdel-Majid , Hagedorn Martin , Prats Hervé , Bikfalvi Andreas
Published: March 2023

Impact of CXCR3 overexpression in MIA PaCa-2 cells in vitro and in vivo
Supplementary Figure 3 from miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer
Authors: Adams Brian D. , Wali Vikram B. , Cheng Christopher J. , Inukai Sachi , Booth Carmen J. , Agarwal Seema , Rimm David L. , Győrffy Balázs , Santarpia Libero , Pusztai Lajos , Saltzman W. Mark , Slack Frank J.
Published: March 2023

Figure S3, Related to Figure 4. A, c-SRC expression in normal (HFF and MCF-10A), luminal-A (MCF-7), LAR-TNBC (MDA-MB-453), and mesenchymal-TNBC (MDA-MB-231, BT-549, and Hs578T) cell lines. Expression was normalized to GAPDH and made relative to c-SRC expression in HFF lines. B-C, Clonogenic assays in Hs578T (B), and MDA-MB-436 (C) TNBC cells after miR-34a transfection and treatment with Dasatnib (left panels) and paclitaxel (right panel) or as a control HeLa cells after dasatinib treatment (C, right panel). D-E, Assessment of miR-34a target genes in MDA-MB-231 cells after 72 hours of dasatinib treatment (D), or miR-34a levels after 72 hours paclitaxel treatment (E). F, miR-34a promoter luciferase assays in MDA-MB-31 cells after dasatinib treatment. G-H, Spearman rank correlation analysis of SRC levels in cell lines described in Figure 1A (G), and in all breast cancer samples in the Metabric dataset (H). I, Comparable decreases in phospho-Tyr416 active c-SRC, non-phospho-Tyr527 c-SRC, and total c-SRC are observed in MDA-MB-231 cells transfected with 15nM miR-34a versus miR-Scr control, as determined by Western blot analysis. J, Schematic highlighting the miR-34a-c-SRC double-negative feedback loop present in MSL TNBC cells, which can be influenced by exogenous addition of miR-34a, or by dasatinib treatment. * Indicates p<0.05, as compared to control conditions.
Supplementary Figure 2 from miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer
Authors: Adams Brian D. , Wali Vikram B. , Cheng Christopher J. , Inukai Sachi , Booth Carmen J. , Agarwal Seema , Rimm David L. , Győrffy Balázs , Santarpia Libero , Pusztai Lajos , Saltzman W. Mark , Slack Frank J.
Published: March 2023

Figure S2, Related to Figure 2. A-F, Functional characterization of miR-34a re-introduction in additional TNBC and non-TNBC cell lines by way of Matrigel-invasion (A), soft agar growth (B), and BrdU labeling (C) experiments. For BrdU assays, we observed only a 5-10% accumulation of BrdU-positive cells 4 days post-transfection. SA-β-gal assays on MDA-MB-157 (D), and BT-20 (E, left panel) TNBC cells, as compared to MCF-7 luminal-A cells (E, right panel). F, MCF-7 cells stably transfected with either a miR-34a (miR-34a SP) or a control (Empty SP) reporter/sponge construct was assayed for SA-β-gal activity. Two independent miR-34a SP pools were generated. G, Luciferase reporter assays indicative of miR-34a activity in all TNBC, luminal, and normal cell lines used in this study. H, miRNA levels in MDA-MB-231, MDA-MB-436, and BT-549 TNBC cells or BT-474 and MCF-7 Luminal-A cells 72 hours after 10nM miR-34a or miR-Scr transfection. In TNBC cells miR-34a expressing lines harbored lower levels of miR-17/92 family members as compared to miR-Scr treated lines. * Indicates p<0.05, as compared to control conditions.
Fig.S5 from Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer
Authors: Quemener Cathy , Baud Jessica , Boyé Kevin , Dubrac Alexandre , Billottet Clotilde , Soulet Fabienne , Darlot Florence , Dumartin Laurent , Sire Marie , Grepin Renaud , Daubon Thomas , Rayne Fabienne , Wodrich Harald , Couvelard Anne , Pineau Raphael , Schilling Martin , Castronovo Vincent , Sue Shih-Che , Clarke Kim , Lomri Abderrahim , Khatib Abdel-Majid , Hagedorn Martin , Prats Hervé , Bikfalvi Andreas
Published: March 2023

Effect of CXCL4L1 and CXCL4 on apoptosis in pancreatic adenocarcinoma cells and endothelial cells
Fig.S3 from Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer
Authors: Quemener Cathy , Baud Jessica , Boyé Kevin , Dubrac Alexandre , Billottet Clotilde , Soulet Fabienne , Darlot Florence , Dumartin Laurent , Sire Marie , Grepin Renaud , Daubon Thomas , Rayne Fabienne , Wodrich Harald , Couvelard Anne , Pineau Raphael , Schilling Martin , Castronovo Vincent , Sue Shih-Che , Clarke Kim , Lomri Abderrahim , Khatib Abdel-Majid , Hagedorn Martin , Prats Hervé , Bikfalvi Andreas
Published: March 2023

Cocultures of Panc-1 cells with myofibroblasts and expression analysis
Supplementary Figure S9 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: March 2023

ELF4 mutants do not act in a dominant-negative manner.
Supplementary Movie 1 from Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells
Authors: Cheng Chun-Ting , Kuo Ching-Ying , Ouyang Ching , Li Chien-Feng , Chung Yiyin , Chan David C. , Kung Hsing-Jien , Ann David K.
Published: March 2023

Movie 1. Time-lapse imaging of MDA-MB-231 cells in complete medium.
Supplementary Figure S6 from Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer
Authors: Ando Mizuo , Kawazu Masahito , Ueno Toshihide , Koinuma Daizo , Ando Koji , Koya Junji , Kataoka Keisuke , Yasuda Takahiko , Yamaguchi Hiroyuki , Fukumura Kazutaka , Yamato Azusa , Soda Manabu , Sai Eirin , Yamashita Yoshihiro , Asakage Takahiro , Miyazaki Yasushi , Kurokawa Mineo , Miyazono Kohei , Nimer Stephen D. , Yamasoba Tatsuya , Mano Hiroyuki
Published: March 2023

Suppression of ELF4 does not affect cell growth
Movie 1 from Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
Authors: Bliss Sarah A. , Sinha Garima , Sandiford Oleta A. , Williams Lisa M. , Engelberth Daniel J. , Guiro Khadidiatou , Isenalumhe Leidy L. , Greco Steven J. , Ayer Seda , Bryan Margarette , Kumar Rakesh , Ponzio Nicholas M. , Rameshwar Pranela
Published: March 2023

Nanoparticle Tracking Analysis using the Nanosight
Supplementary Figures S1-5 from Statin-Induced Cancer Cell Death Can Be Mechanistically Uncoupled from Prenylation of RAS Family Proteins
Authors: Yu Rosemary , Longo Joseph , van Leeuwen Jenna E. , Mullen Peter J. , Ba-Alawi Wail , Haibe-Kains Benjamin , Penn Linda Z.
Published: March 2023

Supplementary Figures S1-5
Supplemental Figures and Table from Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem–like Cells Marked by DCLK1 Kinase
Authors: Weygant Nathaniel , Ge Yang , Qu Dongfeng , Kaddis John S. , Berry William L. , May Randal , Chandrakesan Parthasarathy , Bannerman-Menson Edwin , Vega Kenneth J. , Tomasek James J. , Bronze Michael S. , An Guangyu , Houchen Courtney W.
Published: March 2023

Supplemental material containing a flowchart for how the 15-miRNA signature was generated, a table of pertinent patient clinical data, and a forest plot of hazard ratios of high-risk colon, pancreatic, and stomach cancer patients with high miRNA signatures.
Supplemental Figure Legends from Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation
Authors: Xiao Qian , Zhou Donger , Rucki Agnieszka A. , Williams Jamila , Zhou Jiaojiao , Mo Guanglan , Murphy Adrian , Fujiwara Kenji , Kleponis Jennifer , Salman Bulent , Wolfgang Christopher L. , Anders Robert A. , Zheng Shu , Jaffee Elizabeth M. , Zheng Lei
Published: March 2023

Figure S1. Representative pyrosequencing results. (A) Pyrosequencing of SOCS1 methylation in MSCs. (B) Pyrosequencing of SOCS1 methylation in MSCs after co-cultured with Panc10.05Tumor. (C) Experimental standards of pyrosequencing of SOCS1 methylation. Figure S2. DNMT1 mRNA expression in MSC cells following shRNA knockdown of DNMT1. DNMT1 mRNA expression was quantified by qPCR. Shown are the relative ratios of DNMT1 in MSCs with DNMT1 shRNA (shDNMT1) to that in MSCs with control shRNA. GAPDH expression was used for normalization. Figure S3. Pathways most significantly upregulated in CAFs upon co-culturing with PDAC tumor cells. The microarray gene expression data obtained from CAFs and MSCs before and after co-culturing with PDAC tumor cells were analyzed by the Ingenuity Pathway Analysis Software. Figure S4. SOCS1 expression in MSC cells following shRNA knockdown of SOCS1. SOCS1 expression was examined by Western blot analysis and quantified by using the ImageJ software. The relative ratio (RR) of SOCS1 protein expression in cells with SOCS1 shRNA to that in cells with control shRNA (control) is shown.
Supplemental figure legends from Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models
Authors: Li Fu , Emmerton Kim K. , Jonas Mechthild , Zhang Xinqun , Miyamoto Jamie B. , Setter Jocelyn R. , Nicholas Nicole D. , Okeley Nicole M. , Lyon Robert P. , Benjamin Dennis R. , Law Che-Leung
Published: March 2023

Figure legends for Supplemental Figures S1-S3
Supplemental Figure 3 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

Clonal evolution of mutations from diagnosis to relapse. These graphs depict the Variant Allele Frequency (VAF) of each patient's mutations at diagnosis and relapse. Note: Mutations absent at diagnosis or relapse are depicted with VAF of zero. Gene names are noted to the left of each variant and are available in Supplemental Table 2.
Supplementary movie 1 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

Molecular dynamics simulation of H3K9me2 binding to unmodified GLP-ARD. These movies are related to main Fig. 3D.
Supplementary table 7 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

Primers used for SV validation experiments
Supplementary table 6 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

IVA disease analysis report
Supplementary table 4 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

Somatic mutations validated by Sanger sequencing
Supplementary Figure S4 from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
Authors: Dermawan Josephine Kam Tai , Hitomi Masahiro , Silver Daniel J. , Wu Qiulian , Sandlesh Poorva , Sloan Andrew E. , Purmal Andrei A. , Gurova Katerina V. , Rich Jeremy N. , Lathia Justin D. , Stark George R. , Venere Monica
Published: March 2023

Serum increased asymmetric cell division in GSCs during mitosis.
Supplementary Figure S2 from Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models
Authors: Dermawan Josephine Kam Tai , Hitomi Masahiro , Silver Daniel J. , Wu Qiulian , Sandlesh Poorva , Sloan Andrew E. , Purmal Andrei A. , Gurova Katerina V. , Rich Jeremy N. , Lathia Justin D. , Stark George R. , Venere Monica
Published: March 2023

(A) GSCs are more sensitive to lapatinib compared to NSTCs. (B) EGFR protein levels in CD133+ and CD133- cells.
Supplemental Table 2 from miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis
Authors: Tellez Carmen S. , Juri Daniel E. , Do Kieu , Picchi Maria A. , Wang Teresa , Liu Gang , Spira Avrum , Belinsky Steven A.
Published: March 2023

PCR Primer Sequences for COBRA, MSP, and ChIP Assays.
Supplemental Figure Legends from miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis
Authors: Tellez Carmen S. , Juri Daniel E. , Do Kieu , Picchi Maria A. , Wang Teresa , Liu Gang , Spira Avrum , Belinsky Steven A.
Published: March 2023

Supplemental Figure 1. Analysis of miR-196b, miR-34c-5p, miR-497/195 hypermethylation in lung cancer cell lines, PBMC, and NBEC. Supplemental Figure 2. Analysis of miR-196b and miR-34c-5p hypermethylation in NSCLC. Supplemental Table 1. Established In Vitro Model of Pre-Malignant Lung Cancer. Supplemental Table 2. PCR Primer Sequences for COBRA, MSP, and ChIP Assays.
Supplemental Figure 2 from miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis
Authors: Tellez Carmen S. , Juri Daniel E. , Do Kieu , Picchi Maria A. , Wang Teresa , Liu Gang , Spira Avrum , Belinsky Steven A.
Published: March 2023

Analysis of miR-196b and miR-34c-5p hypermethylation in NSCLC.
Supplementary Figure 3 from Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Authors: Mattina James , MacKinnon Nathalie , Henderson Valerie C. , Fergusson Dean , Kimmelman Jonathan
Published: March 2023

Effect sizes for all tumor volume experiments (n=97).
Supplementary Figure 1 from Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Authors: Mattina James , MacKinnon Nathalie , Henderson Valerie C. , Fergusson Dean , Kimmelman Jonathan
Published: March 2023

PRISMA flow diagram.
Supplementary Material and Methods. from Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1
Authors: Oladimeji Peter , Skerl Rebekah , Rusch Courtney , Diakonova Maria
Published: March 2023

This file contains Supplementary Material and Methods.
Supplementary Figure 7 from Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
Authors: Beyranvand Nejad Elham , van der Sluis Tetje C. , van Duikeren Suzanne , Yagita Hideo , Janssen George M. , van Veelen Peter A. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Arens Ramon
Published: March 2023

Cisplatin treatment does not affect the expression of costimulatory molecules on tumor cells, total myeloid cells of spleen and TDLN in vivo.
Supplementary Figure Legend from Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1
Authors: Oladimeji Peter , Skerl Rebekah , Rusch Courtney , Diakonova Maria
Published: March 2023

This file contains Supplementary Figure Legend.
Supplementary Figure 6 from Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
Authors: Beyranvand Nejad Elham , van der Sluis Tetje C. , van Duikeren Suzanne , Yagita Hideo , Janssen George M. , van Veelen Peter A. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Arens Ramon
Published: March 2023

Effects of cisplatin on the tumor microenvironment.
Supplementary Figure 3 from Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells
Authors: Beyranvand Nejad Elham , van der Sluis Tetje C. , van Duikeren Suzanne , Yagita Hideo , Janssen George M. , van Veelen Peter A. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Arens Ramon
Published: March 2023

Cisplatin-induced cell death enhances T-cell activation by upregulating CD70, CD80 and CD86 costimulatory molecules.
Supplemetary Table S1 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

Gene Ontology of microarray data by DAVID analysis.
Supplemental Table from Frequency and Dynamics of Leukemia-Initiating Cells during Short-term Ex Vivo Culture Informs Outcomes in Acute Myeloid Leukemia Patients
Authors: Griessinger Emmanuel , Anjos-Afonso Fernando , Vargaftig Jacques , Taussig David C. , Lassailly François , Prebet Thomas , Imbert Véronique , Nebout Marielle , Vey Norbert , Chabannon Christian , Filby Andrew , Bollet-Quivogne Frederic , Gribben John G. , Peyron Jean-François , Bonnet Dominique
Published: March 2023

Supplemental Table
Supplementary Table S2 from Label-Free Neurosurgical Pathology with Stimulated Raman Imaging
Authors: Lu Fa-Ke , Calligaris David , Olubiyi Olutayo I. , Norton Isaiah , Yang Wenlong , Santagata Sandro , Xie X. Sunney , Golby Alexandra J. , Agar Nathalie Y.R.
Published: March 2023

Diagnostic features revealed from label-free SRS imaging versus H&E staining of human brain tumors.
Table S2 from Secondary Tumors Arising in Patients Undergoing BRAF Inhibitor Therapy Exhibit Increased BRAF–CRAF Heterodimerization
Authors: Boussemart Lise , Girault Isabelle , Malka-Mahieu Hélène , Mateus Christine , Routier Emilie , Rubington Margot , Kamsu-Kom Nyam , Thomas Marina , Tomasic Gorana , Agoussi Sandrine , Breckler Marie , Laporte Mélanie , Lacroix Ludovic , Eggermont Alexander M. , Cavalcanti Andrea , Grange Florent , Adam Julien , Vagner Stéphan , Robert Caroline
Published: March 2023

Tumoral and non tumoral biospies from patients treated with or without BRAF inhibitors: Mutational status, pERK level and BRAF-CRAF PLA score.
Figure S9 from Restraining Network Response to Targeted Cancer Therapies Improves Efficacy and Reduces Cellular Resistance
Authors: Das Tirtha K. , Esernio Jessica , Cagan Ross L.
Published: March 2023

Figure S9 shows 'network brake drugs' affects Sox2 in thyroid cells; have little effect in the absence of targeted therapy
Figure S4&S5 from Restraining Network Response to Targeted Cancer Therapies Improves Efficacy and Reduces Cellular Resistance
Authors: Das Tirtha K. , Esernio Jessica , Cagan Ross L.
Published: March 2023

Figure S4, S5, shows drug combinations that restrain or hyperactivate different cellular pathways in flies
Supplementary Figure S3 from Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
Authors: Huang Yu-Hung , Peng Weidan , Furuuchi Narumi , Gerhart Jacquelyn , Rhodes Kelly , Mukherjee Neelanjan , Jimbo Masaya , Gonye Gregory E. , Brody Jonathan R. , Getts Robert C. , Sawicki Janet A.
Published: March 2023

Supplementary Fig. S3. A. HuR mRNA levels in parental and transfected OVCAR3 cells upon shHuR induction with 1mg/ml DOX. PAR = parental. B. Western blots of cell lysates following incubation with various concentrations of doxycycline. C. OVCAR3 toxicity following incubation with various concentrations of doxycycline.
Supplementary figures legends from Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells
Authors: Pang Mei-Fong , Siedlik Michael J. , Han Siyang , Stallings-Mann Melody , Radisky Derek C. , Nelson Celeste M.
Published: March 2023

Supplementary figures legends
Supplementary Figure S2 from Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
Authors: Huang Yu-Hung , Peng Weidan , Furuuchi Narumi , Gerhart Jacquelyn , Rhodes Kelly , Mukherjee Neelanjan , Jimbo Masaya , Gonye Gregory E. , Brody Jonathan R. , Getts Robert C. , Sawicki Janet A.
Published: March 2023

Supplementary Fig. S2. A. HuR mRNA levels measured by RT-PCR in A2780 transiently-transfected with siHuR and siCtrl. B. Constitutively expressed shHuR maintains inhibition of HuR expression in ovarian tumor cells. Western blots of total cell lysates of parental and shHuR-constitutively expressing A2780, OVCAR5, and OVCA420 cells at various passage numbers. C. HuR mRNA levels measured by RT-PCR in late passages of A2780 and OVCAR5 cells expressing shHuRc or shCtrl. * = p<0.0005
Figure S4 from Tissue Stiffness and Hypoxia Modulate the Integrin-Linked Kinase ILK to Control Breast Cancer Stem-like Cells
Authors: Pang Mei-Fong , Siedlik Michael J. , Han Siyang , Stallings-Mann Melody , Radisky Derek C. , Nelson Celeste M.
Published: March 2023

Depleting ILK inhibits PI3K signaling in human breast cancer cells. Immunoblotting analysis for phosphorylated and total Akt in (A) MDA-MB-231-shctrl or MDA-MB-231-shILK cells and (B) MDA-MB-231 cells treated with or without LY294002 (50 µM). Transcript levels of (C) ITGB1, (D) ILK, (E) CD44, (F) Nanog, and (G) CD49f in MDA-MB-231 cells treated with or without LY294002 and cultured on soft or stiff substrata under normoxia or hypoxia. Phase contrast images and quantification of (H) secondary mammospheres and (I) colonies formed in soft agar by MDA-MB-231 cells treated with or without LY294002 under normoxia or hypoxia. Scale bars, 50 µm. Shown are mean (plus minus) s.e.m. *, P<0.05; **, P<0.01; ***, P<0.001.
Supplementary Figure S1 from Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
Authors: Huang Yu-Hung , Peng Weidan , Furuuchi Narumi , Gerhart Jacquelyn , Rhodes Kelly , Mukherjee Neelanjan , Jimbo Masaya , Gonye Gregory E. , Brody Jonathan R. , Getts Robert C. , Sawicki Janet A.
Published: March 2023

Supplementary Fig. S1. Location of HuR (human) inhibitory oligonucleotides.