bluuebunny/crossref_metadata_2025 huggingface dataset:
Length of hospital stay after hip fracture and readmission rates of persons with and without Alzheimer’s disease: a matched cohort study
Authors: Rajamaki Blair , Koponen Marjaana , Hartikainen Sirpa , Tolppanen Anna-Maija
Published: June 2020

Background

Hospital length of stays (LOS) for incident of hip fracture are decreasing, but it is unknown if these changes have negative impacts on vulnerable older patient populations, like those with Alzheimer’s disease (AD). We aimed to assess if persons with and without AD have different hospital LOS for hip fracture, and is the LOS associated with hospital readmissions.

Methods

Utilizing register-based data for a matched cohort study nested in the Medication use and Alzheimer’s disease study (MEDALZ), we collected all community-dwelling persons in Finland diagnosed with AD during 2005–2012, had incident of first hip fracture between 2005 and 2015 after AD diagnosis, and were discharged alive from an acute care hospital. Hospital LOS and hospital readmissions within 30-days and 90-days were compared between those with and without AD and risk of readmission was assessed using binary logistic regression analysis.

Results

In this matched cohort study of 12,532 persons (mean age 84.6 years (95% CI: 84.5–84.7), 76.8% women), the median LOS in an acute care hospital was 1 day shorter for those with AD (median 4 days, IQR 3–7) than those without AD (median 5 days, IQR 3–7) (P < 0.001). However, the AD cohort had respectively 6 days and 5 days longer median LOS in a community hospital, and total hospital stay compared to the non-AD cohort (P < 0.001 for all comparisons). Those with AD had fewer readmissions within 30-days (10.7%) and 90-days (16.9%) compared to those without AD (13.3% 30-days and 20.7% 90-days) (P < 0.001 for all comparisons). Both cohorts had a reduced readmission risk within 30-days when the LOS in an acute care hospital was 4–14 days, compared to a LOS less than 4 days.

Conclusions

Persons with AD had shorter acute care hospital LOS, but had longer LOS in a community hospital setting compared to those without AD, which is similar to other findings when comparing total hospital LOS. These findings imply that short LOS in acute care hospitals may be associated with poor health outcomes for vulnerable older populations after hip fracture.
Epidemiological and clinical features of 2019 novel coronavirus diseases (COVID-19) in the South of Iran
Authors: Shahriarirad Reza , Khodamoradi Zohre , Erfani Amirhossein , Hosseinpour Hamidreza , Ranjbar Keivan , Emami Yasaman , Mirahmadizadeh Alireza , Lotfi Mehrzad , Shirazi Yeganeh Babak , Dorrani Nejad Abolfazl , Hemmati Abdolrasool , Ebrahimi Mostafa , Moghadami Mohsen
Published: June 2020

Background

In March 2020, the WHO declared the novel coronavirus (COVID-19) outbreak a global pandemic. Although the number of infected cases is increasing, information about its clinical characteristics in the Middle East, especially in Iran, a country which is considered to be one of the most important focal points of the disease in the world, is lacking. To date, there is no available literature on the clinical data on COVID-19 patients in Iran.

Methods

In this multicenter retrospective study, 113 hospitalized confirmed cases of COVID-19 admitted to university affiliated hospitals in Shiraz, Iran from February 20 to March 20 were entered in the study.

Results

The mean age was 53.75 years and 71 (62.8%) were males. The most common symptoms at onset were fatigue (75: 66.4%), cough (73: 64.6%), and fever (67: 59.3%). Laboratory data revealed significant correlation between lymphocyte count (P value = 0.003), partial thromboplastin time (P value = 0.000), international normalized ratio (P value = 0.000) with the severity of the disease. The most common abnormality in chest CT scans was ground-glass opacity (77: 93.9%), followed by consolidation (48: 58.5%). Our results revealed an overall 8% (9 out of 113 cases) mortality rate among patients, in which the majority was among patients admitted to the ICU (5: 55.6%).

Conclusion

Evaluating the clinical data of COVID-19 patients and finding the source of infection and studying the behavior of the disease is crucial for understanding the pandemic.
Work ability and percentage of hours worked related to limitations in patients with upper extremity musculoskeletal disorders: a cross-sectional cohort study
Authors: van Schaaijk A. , Nieuwenhuijsen K. , Frings-Dresen M. H. W.
Published: June 2020

Background

The aim of this study was to assess the relationship between self-reported work ability and hours worked at the current time in Upper Extremity Musculoskeletal Disorders (UEMSD) patients. To further investigate this relationship, the association of work ability and working hours with several limitations in daily and working life were explored.

Methods

In this cross-sectional cohort study, a questionnaire was sent out to members of the UEMSD patient organisation, containing self-reported work ability, questions on working hours and limitations in work due to UEMSD. Limitations were measured with the Disabilities of Arm Shoulder and Hand questionnaire, ShortForm-36 subscales, and common hand grasps or grips. Work ability was measured with the work ability score, while worked hours were operationalised as the percentage of hours worked compared to fulltime. The correlation between worked hours and work ability was tested with the Pearson correlation coefficient. Variance in work ability and the hours worked were explained by limitations and assessed with two linear regression analyses.

Results

Based on data of 794 respondents a moderate correlation was found between work ability and worked hours r = 0.46; 95% CI [0.40, 0.53]. Models including limitations explained 52 and 21% of total variance in work ability and worked hours, respectively. Variance in both can be explained by the degree of difficulties performing daily activities at work, limitations in daily activities as a consequence of health issues and the ability to perform a precision grip. Additionally, work ability can be explained by limitations at work and other daily activities due to physical health issues, while the percentage of hours can additionally be explained by the ability to grasp a large object with one hand, the ability to use a keyboard, and the subject’s gender.

Conclusions

The number of worked hours does not fully match the work ability. Although they share three predictors, work ability and worked hours seem to be based on different aspects. Compared to work hours, work ability is more strongly related to limitations in daily activities and work. Taking self-reported work ability into account can improve the fit between work limitations and work hours.
Research on Teleconsultation service quality based on multi-granularity linguistic information: the perspective of regional doctors
Authors: Lu Wei , Wang Xin-pu , Zhao Jie , Zhai Yun-kai
Published: June 2020

Background

Due to the increasing complexity in socioeconomic environments and the ambiguity in human cognition, decision makers prefer to give linguistic cognitive information with different granularities according to their own preferences. Consequently, to consider the uncertainty and preferences in the evaluation process, a method based on Multi-Granularity Linguistic Information (MGLI) for evaluating teleconsultation service quality is proposed, which provides a new research direction for scientific evaluation and improvement of teleconsultation service quality.

Methods

Firstly, this paper explored a service quality evaluation system from the perspective of regional doctors. And then considering the uncertainty and preferences of decision makers, MGLI was used to optimize the index system according to the similarity degree between the linguistic evaluation information and a given linguistic term set. Finally, the empirical research was conducted using Henan Province Telemedicine Center of China (HTCC) as an example to identify the direction for improving the service quality in teleconsultation.

Results

This study found that the number of consulting rooms, attitude of operators, consultation duration, charges, and attitude of experts are the key factors affecting the quality of teleconsultation service.

Conclusions

Suggestions for improving the quality of teleconsultation service are put forward in terms of optimizing the allocation of consulting rooms, improving regional doctors’ experience and standardizing charging standards, which provides a new direction for improving the quality of teleconsultation service.
Examining innovation in hospital units: a complex adaptive systems approach
Authors: Glover Wiljeana Jackson , Nissinboim Noa , Naveh Eitan
Published: June 2020

Background

We are in an innovation age for healthcare delivery. Some note that the complexity of healthcare delivery may make innovation in this setting more difficult and may require more adaptive solutions. The aim of this study is to examine the relationship between unit complexity and innovation, using a complex adaptive systems approach in a hospital setting.

Methods

We conducted a quantitative study of 31 hospital units within one hospital and use complex adaptive systems (CAS) theory to examine how two CAS factors, autonomy and performance orientation, moderate the relationship between unit complexity and innovation.

Results

We find that unit complexity is associated with higher innovation performance when autonomy is low rather than high. We also find that unit complexity is associated with higher innovation performance when performance orientation is high rather than low. Our findings make three distinct contributions: we quantify the influence of complexity on innovation success in the health care sector, we examine the impact of autonomy on innovation in health care, and we are the first to examine performance orientation on innovation in health care.

Conclusions

This study tackles the long debate about the influence of complexity on healthcare delivery, particularly innovation. Instead of being subject to the influence of complexity with no means of making progress or gaining control, hospitals looking to implement innovation programs should provide guidance to teams and departments regarding the type of innovation sought and provide support in terms of time and management commitment. Hospitals should also find ways to promote and make successful pilot implementations of such innovations visible in the organization. A close connection between the targeted innovation and the overall success and performance of the hospital unit is ideal.
Antibiotic prescribing in UK care homes 2016–2017: retrospective cohort study of linked data
Authors: Smith Catherine M. , Williams Haydn , Jhass Arnoupe , Patel Selina , Crayton Elise , Lorencatto Fabiana , Michie Susan , Hayward Andrew C. , Shallcross Laura J. ,   on behalf of the Preserving Antibiotics through Safe Stewardship group, Anderson N. , Atkins L. , Conolly A. , Crayton E. , Denaxas S. , Dutey-Magni P. , Elsay N. , Forbes G. , Fragaszy E. B. , Freemantle N. , Fuller C. , Gill M. , Hayward A. H. , Horne R. , Jhass A. , Kostkova P. , Lorencatto F. , Michie S. , Mindell J. , Richardson M. , Robson J. , Rockenschaub P. , Royston C. , Shallcross L. J. , Smith C. M. , Sutton E. , Thomas J. , Tarrant C. , Traina R. , Richardson E. , West J. , Williams H.
Published: June 2020

Background

Older people living in care homes are particularly susceptible to infections and antibiotics are therefore used frequently for this population. However, there is limited information on antibiotic prescribing in this setting. This study aimed to investigate the frequency, patterns and risk factors for antibiotic prescribing in a large chain of UK care homes.

Methods

Retrospective cohort study of administrative data from a large chain of UK care homes (resident and care home-level) linked to individual-level pharmacy data. Residents aged 65 years or older between 1 January 2016 and 31 December 2017 were included. Antibiotics were classified by type and as new or repeated prescriptions. Rates of antibiotic prescribing were calculated and modelled using multilevel negative binomial regression.

Results

13,487 residents of 135 homes were included. The median age was 85; 63% residents were female. 28,689 antibiotic prescriptions were dispensed, the majority were penicillins (11,327, 39%), sulfonamides and trimethoprim (5818, 20%), or other antibacterials (4665, 16%). 8433 (30%) were repeat prescriptions. The crude rate of antibiotic prescriptions was 2.68 per resident year (95% confidence interval (CI) 2.64–2.71). Increased antibiotic prescribing was associated with residents requiring more medical assistance (adjusted incidence rate ratio for nursing opposed to residential care 1.21, 95% CI 1.13–1.30). Prescribing rates varied widely by care home but there were no significant associations with the care home-level characteristics available in routine data.

Conclusions

Rates of antibiotic prescribing in care homes are high and there is substantial variation between homes. Further research is needed to understand the drivers of this variation to enable development of effective stewardship approaches that target the influences of prescribing.
The effects of inflammatory bowel disease on caregivers: significant burden and loss of productivity
Authors: Zand Aria , Kim Brian J. , van Deen Welmoed K. , Stokes Zachary , Platt Anya , O’Hara Shelby , Khong Harrison , Hommes Daniel W.
Published: June 2020

Background

Caregiver burden is the emotional, physical, practical, and/or financial burden associated with taking care of a patient with a chronic condition. Limited literature on caregiver burden in Inflammatory Bowel Diseases (IBD) has accounted for some predictors, but its effect on work productivity (absenteeism and presenteeism) is unknown.

Methods

In a prospective study, patients and their respective caregivers were surveyed from November 2015 until July 2017. Data on demographics, work productivity, quality of life, disease activity, caregiver burden and productivity were collected. The burden on caregivers was assessed and associations between caregiver productivity and caregiver burden were analyzed. Additionally, predictors for caregiver burden were identified.

Results

One hundred two IBD patients and their respective caregiver were included. In total, 39% of IBD caregivers experienced burden. Caregivers with burden experienced significantly more absenteeism and presenteeism (65 and 85% respectively). Furthermore, 51% of caregivers felt that they should be doing more for their care recipient and felt they could do a better job at caregiving. Predictors of burden included race/ethnicity, history of fistulas, diagnosis of ulcerative colitis, higher caregiver education, and hours spent caregiving.

Conclusion

Caregivers with burden had significantly more productivity decrease compared to those without burden. Additionally, the majority of caregivers feel they should be providing more and better care for their recipients. The development of strategies to address caregiver’s distress and perceived burden when caring for IBD patients is warranted.
Evaluating process fidelity during the implementation of Group Antenatal Care in Mexico
Authors: Fuentes-Rivera Evelyn , Heredia-Pi Ileana , Andrade-Romo Zafiro , Alcalde-Rabanal Jacqueline , Bravo Lourdes , Jurkiewicz Laurie , Darney Blair G.
Published: June 2020

Background

CenteringPregnancy (CP) is a group antenatal care (G-ANC) model that has proven beneficial for mothers and their newborns. We conducted a feasibility study beginning in 2016 as part of the Mexican effort to implement G-ANC locally. This study reports on fidelity to the essential elements of CP during its implementation in Mexico.

Methods

We collected prospective data using a standardized checklist at four primary-care centers that implemented our adapted G-ANC model. We performed a descriptive analysis of fidelity to 28 processes per G-ANC session (71 sessions made up of 10 groups and 129 women across 4 health centers). We calculated fidelity to each process as a proportion with 95% confidence intervals. We present overall results and stratified by health center and by facilitation team.

Results

Overall fidelity to the G-ANC intervention was 82%, with variability by health center (78–88%). The elements with the highest fidelity were having space for activities such as checking vital signs, conversation in a circle, and medical check-ups (100% each) and the element with the lowest fidelity was using music to enhance privacy (27.3%). Fidelity was not significantly different by center.

Conclusions

Our study suggests good model fidelity during the implementation of G-ANC in Mexico. Our findings also contribute useful information about where to focus efforts in the future to maintain and improve G-ANC model fidelity.
Biosurfactant from vaginal Lactobacillus crispatus BC1 as a promising agent to interfere with Candida adhesion
Authors: De Gregorio Priscilla Romina , Parolin Carola , Abruzzo Angela , Luppi Barbara , Protti Michele , Mercolini Laura , Silva Jessica Alejandra , Giordani Barbara , Marangoni Antonella , Nader-Macías María Elena Fátima , Vitali Beatrice
Published: June 2020

Background

Lactobacillus spp. dominating the vaginal microbiota of healthy women contribute to the prevention of urogenital and sexually transmitted infections. Their protective role in the vagina can be mediated by Lactobacillus cells themselves, metabolites or bacterial components, able to interfere with pathogen adhesion and infectivity. Vulvovaginal candidiasis (VVC) is a common genital infection, caused by the overgrowth of opportunistic Candida spp. including C. albicans, C. glabrata, C. krusei and C. tropicalis. Azole antifungal drugs are not always efficient in resolving VVC and preventing recurrent infections, thus alternative anti-Candida agents based on vaginal probiotics have gained more importance. The present work aims to chemically characterize the biosurfactant (BS) isolated from a vaginal Lactobacillus crispatus strain, L. crispatus BC1, and to investigate its safety and antiadhesive/antimicrobial activity against Candida spp., employing in vitro and in vivo assays.

Results

BS isolated from vaginal L. crispatus BC1 was characterised as non-homogeneous lipopeptide molecules with a critical micellar concentration value of 2 mg/mL, and good emulsification and mucoadhesive properties. At 1.25 mg/mL, the BS was not cytotoxic and reduced Candida strains’ ability to adhere to human cervical epithelial cells, mainly by exclusion mechanism. Moreover, intravaginal (i.va.) inoculation of BS in a murine experimental model was safe and did not perturb vaginal cytology, histology and cultivable vaginal microbiota. In the case of i.va. challenge of mice with C. albicans, BS was able to reduce leukocyte influx.

Conclusions

These results indicate that BS from vaginal L. crispatus BC1 is able to interfere with Candida adhesion in vitro and in vivo, and suggest its potential as a preventive agent to reduce mucosal damage occasioned by Candida during VVC.
The prognostic value of ITGA and ITGB superfamily members in patients with high grade serous ovarian cancer
Authors: Zhu Tingting , Chen Ruifang , Wang Jieyu , Yue Huiran , Lu Xin , Li Jun
Published: June 2020

Background

Deregulation of integrins signaling had been documented to participate in multiple fundamental biological processes, and the aberrant expression of integrin family members were linked to the prognosis of various cancers. However, the role of integrins in predicting progression and prognosis of ovarian cancer patients are still largely elusive. This study is aimed to explore the prognostic values of ITGA and ITGB superfamily members in high grade serous ovarian cancers (HGSOC).

Methods

GSE26712 dataset was used to determine the differential expression of ITGA and ITGB superfamily member between HGSOC and normal counterparts. The Cancer Genome Altas (TGGA) and GSE9891 datasets were used to determine the prognostic values of ITGA and ITGB superfamily members in HGSOC, followed by the development of nomograms predictive of recurrence free survival (RFS) and overall survival (OS).

Results

ITGA6 and ITGB5 expression were significantly downregulated in HGSOC compared with that in normal counterparts. In contrast, ITGA2, ITGA5, ITGA7, ITGA8, ITGA9, ITGA10, ITGB3, ITGB4, ITGB6, and ITGB8 were all significantly upregulated in HGSOC compared with that in normal counterparts. Both univariable and multivariable analysis indicated that ITGB1 was associated with extended RFS. The ITGB1-related nomogram indicated that ITGB1 had the largest contribution to RFS, followed by FIGO stage and debulking status. The C-index for predicting RFS was 0.55 (95% CI 0.50–0.59) in TCGA dataset (training dataset) and 0.65 (95% CI 0.59–0.72) in GSE9891 dataset (validation dataset), respectively. Regarding OS, ITGB8 was associated with reduced survival suggested by both univariable and multivariable analysis. ITGA7 appeared to be associated with improved survival though without reaching statistical significance. The ITGA7/ITGB8-based nomogram showed that age at initial diagnosis had the largest contribution to OS, followed by ITGB8 and ITGA7 expression. The C-index for predicting OS was 0.65 (95% CI 0.60–0.69) in TCGA dataset (training dataset) and 0.59 (95% CI 0.51–0.66) in GSE9891 dataset (validation dataset), respectively.

Conclusion

In conclusion, ITGB1, ITGA7 and ITGB8 added prognostic value to the traditional clinical risk factors used to assess the clinical outcomes of HGSOC.
Application of smart mosquito monitoring traps for the mosquito forecast systems by Seoul Metropolitan city
Authors: Na Sumi , Yi Hoonbok
Published: June 2020

Background

The purpose of this study, mosquito forecast system implemented by Seoul Metropolitan city, was to obtain the mosquito prediction formula by using the mosquito population data and the environmental data of the past.

Results

For this study, the mosquito population data from April 1, 2015, to October 31, 2017, were collected. The mosquito population data were collected from the 50 smart mosquito traps (DMSs), two of which were installed in each district (Korean, gu) in Seoul Metropolitan city since 2015. Environmental factors were collected from the Automatic Weather System (AWS) by the Korea Meteorological Administration. The data of the nearest AWS devices from each DMS were used for the prediction formula analysis. We found out that the environmental factors affecting the mosquito population in Seoul Metropolitan city were the mean temperature and rainfall. We predicted the following equations by the generalized linear model analysis: ln(Mosquito population) = 2.519 + 0.08 × mean temperature + 0.001 × rainfall.

Conclusions

We expect that the mosquito forecast system would be used for predicting the mosquito population and to prevent the spread of disease through mosquitoes.
The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?
Authors: List Edward O , Berryman Darlene E , Basu Reetobrata , Buchman Mathew , Funk Kevin , Kulkarni Prateek , Duran-Ortiz Silvana , Qian Yanrong , Jensen Elizabeth A , Young Jonathan A , Yildirim Gozde , Yakar Shoshana , Kopchick John J
Published: June 2020

A rare 20K isoform of GH-V (here abbreviated as GHv) was discovered in 1998. To date, only 1 research article has characterized this isoform in vivo, observing that GHv treatment in male high-fat fed rats had several GH-like activities, but unlike GH lacked diabetogenic and lactogenic activities and failed to increase IGF-1 or body length. Therefore, the current study was conducted to further characterize the in vivo activities of GHv in a separate species and in a GH-deficient model (GH-/- mice) and with both sexes represented. GHv-treated GH-/- mice had significant increases to serum IGF-1, femur length, body length, body weight, and lean body mass and reduced body fat mass similar to mice receiving GH treatment. GH treatment increased circulating insulin levels and impaired insulin sensitivity; in contrast, both measures were unchanged in GHv-treated mice. Since GHv lacks prolactin receptor (PRLR) binding activity, we tested the ability of GH and GHv to stimulate the proliferation of human cancer cell lines and found that GHv has a decreased proliferative response in cancers with high PRLR. Our findings demonstrate that GHv can stimulate insulin-like growth factor-1 and subsequent longitudinal body growth in GH-deficient mice similar to GH, but unlike GH, GHv promoted growth without inhibiting insulin action and without promoting the growth of PRLR-positive cancers in vitro. Thus, GHv may represent improvements to current GH therapies especially for individuals at risk for metabolic syndrome or PRLR-positive cancers.
Steroids Regulate SLC2A1 and SLC2A3 to Deliver Glucose Into Trophectoderm for Metabolism via Glycolysis
Authors: Kramer Avery C , Steinhauser Chelsie B , Gao Haijun , Seo Heewon , McLendon Bryan A , Burghardt Robert C , Wu Guoyao , Bazer Fuller W , Johnson Greg A
Published: June 2020

The conceptuses (embryo/fetus and placental membranes) of pigs require energy to support elongation and implantation, and amounts of glucose and fructose increase in the uterine lumen during the peri-implantation period. Conceptuses from day 16 of pregnancy were incubated with either 14C-glucose or 14C-fructose and amounts of radiolabeled CO2 released from the conceptuses measured to determine rates of oxidation of glucose and fructose. Glucose and fructose both transport into conceptuses, and glucose is preferentially metabolized in the presence of fructose, whereas fructose is actively metabolized in the absence of glucose and to a lesser extent in the presence of glucose. Endometrial and placental expression of glucose transporters SLC2A1, SLC2A2, SCL2A3, and SLC2A4 were determined. SLC2A1 messenger RNA (mRNA) and protein, and SLC2A4 mRNA were abundant in the uterine luminal epithelium of pregnant compared to cycling gilts, and increased in response to progesterone and conceptus-secreted estrogen. SLC2A2 mRNA was expressed weakly by conceptus trophectoderm on day 15 of pregnancy, whereas SLC2A3 mRNA was abundant in trophectoderm/chorion throughout pregnancy. Therefore, glucose can be transported into the uterine lumen by SLC2A1, and then into conceptuses by SLC2A3. On day 60 of gestation, the cell-specific expression of these transporters was more complex, suggesting that glucose and fructose transporters are precisely regulated in a spatial-temporal pattern along the uterine-placental interface of pigs to maximize hexose sugar transport to the pig conceptus/placenta.
El desacuerdo en modelos de formación de opiniones: resultados de estática comparativa
Authors: Melguizo Isabel
Published: June 2020

Este artículo estudia la persistencia del desacuerdo en un modelo similar a Melguizo (2019), relajando dos supuestos importantes. Primero, las opiniones iniciales de los individuos son variables aleatorias, y segundo, los individuos pueden tener distintos grados de homofilia. Con respecto a la primera extensión, se encuentra que el desacuerdo persiste con más probabilidad en el atributo que exhibe la mayor media de la distribución de las diferencias en actitudes medias iniciales. Respecto a la segunda, la magnitud del desacuerdo y la velocidad de convergencia en ´el incrementan con respecto al modelo original.
Lockdown life: beyond loss, towards growth
Authors: Greenaway Beth
Published: June 2020

In this month's Patient Story, Beth Greenaway speaks about her experiences of lockdown during the COVID-19 pandemic.
Friends with benefits: choosing a trade association
Authors: Bernstein Adam
Published: June 2020

The saying goes that it is often who you know that gets you ahead. Having friends in high places, then, is theoretically a benefit of joining a trade association—but what is the reality? Adam Bernstein investigates
Libraries: the uncomfortable need to select
Authors: Bernardes José Augusto Cardoso
Published: June 2020

https://doi.org/10.14195/1647-8436_46_47_10
Variantes de um poema juvenil de Mário de Sá-Carneiro
Authors: Do Amaral A. E. Maia
Published: June 2020

Dá-se a conhecer o pequeno núcleo de livros de infância de Mário de Sá-Carneiro (1890-1916) conservado na Biblioteca Geral da Universidade de Coimbra, e alguns versos neles manuscritos que se revelam como variantes inéditas do poema de juventude “Quadras para a Desconhecida”.
Fundo Doutor Luís de Albuquerque da Biblioteca Geral da Universidade de Coimbra
Authors: De Carvalho Maria de Fátima Moura
Published: June 2020

Luís de Albuquerque nascido em 1917 e falecido em 1992, foi um brilhante professor da Faculdade de Ciências da Universidade de Coimbra, embora também colaborasse com a Faculdade de Letras. Foi também Diretor da Biblioteca Geral entre 1978 e 1987, a quem fez a doação da sua Biblioteca Pessoal, composta por monografias, recursos contínuos e manuscritos. O Fundo inclui publicações de áreas muito variadas, mas predominantemente de Ciências Exatas e História.
Mutatis mutandis: os dramas da forma. Nos dois mil anos da morte de Ovídio, criador das Metamorfoses
Authors: Miranda Margarida
Published: June 2020

Ao contrário da sorte de muitas outras obras dos autores greco­‑romanos, as Metamorfoses de Ovídio estiveram sempre presentes na tradição literária europeia. O poema inspirou e continua a inspirar intelectuais e artistas de todos os tempos, incluindo poetas, pintores, escultores, músicos e coreógrafos. Nos últimos anos assistimos ao crescimento do interesse por Ovídio, não apenas enquanto poeta espirituoso dos salões e do amor requintado, mas também enquanto poeta da erudição mitológica aliada à complexidade da natureza humana, sujeita à dor e à morte. Mas a verdade é que a inspiração em Ovídio não atraiu apenas os homens de letras. O tesouro artístico da Europa tem nas Metamorfoses uma das maiores fontes de inspiração. Nenhuma outra obra exerceu tão grande influência sobre a cultura europeia, a literatura e as artes. A influência das Metamorfoses nas artes e na cultura ocidental foi incomensurável, fazendo dela a maior fonte primária dos artistas europeus. Por isso o Festival das Artes teve por bem revisitá­‑la, criando a ocasião para a Exposição que se descreve nestas páginas.
AlmaMater: património bibliográfico e identidade na Universidade de Coimbra
Authors: Miguéis Ana Eva
Published: June 2020

A AlmaMater é a biblioteca digital de fundo antigo da Universidade de Coimbra, apresentada publicamente em julho de 2010. A AlmaMater congrega várias coleções digitais representativas da Biblioteca Geral da Universidade de Coimbra, das bibliotecas de diferentes unidades orgânicas e, também, bibliotecas temáticas, como é o caso da República Digital, História da Ciência ou Mapas Nabais Conde, que assinalam acontecimentos ou factos importantes diversos e que constituem, no seu conjunto, um repositório bibliográfi co de grande valor histórico, bibliográfi co e documental. A Alma- Mater resultou de um propósito muito claro da Universidade de Coimbra, que foi o de promover e facilitar o acesso aos fundos antigos das suas bibliotecas, aos investigadores e ao grande público, e de os disponibilizar através de uma plataforma na Internet, dando a conhecer o importante património bibliográfico da Universidade e reforçando a sua identidade. Os recursos digitais disponibilizados na AlmaMater abarcam um conjunto diversifi cado de documentos – livros, jornais, revistas, fotografias, mapas, gravuras – que vão do Séc. XIII ao séc. XX, sendo possível percorrer todo este intervalo de tempo, de forma ágil e intuitiva. Neste texto, pretende-se abordar os aspetos mais significativos desta biblioteca digital, fazendo referência à sua estrutura e organização, aos fundos bibliográficos que a constituem, aos aspetos e funcionalidades desenvolvidas e às melhorias implementadas ao longo do tempo. Reconhece-se que a experiência adquirida no tratamento do património bibliográfico da Universidade de Coimbra, o acompanhamento dos processos de digitalização, o desenvolvimento de plataformas digitais e a integração de objetos digitais foram fatores determinante para o sucesso deste projeto. Conclui-se, afirmando que a AlmaMater é um projeto de grande importância estratégica, com impacto na divulgação do valioso património cultural da Universidade de Coimbra junto de investigadores nacionais e internacionais, e também junto dos cidadãos, cumprindo deste modo com uma importante função universitária, a de suscitar a curiosidade de novos públicos.
Conceito de obras nas FRBR, RDA e BIBFRAME
Authors: De Carvalho Maria De Fátima Moura
Published: June 2020

Pretendemos fazer uma apresentação da noção de obra nas FRBR (Functional Requirements of Bibliographic Records), RDA (Resource, Description and Acess) e BIBFRAME (Bibliographic Framework Transition Initiative). Este artigo tem como base a dissertação de mestrado apresentada à Faculdade de Letras da Universidade de Coimbra em fevereiro de 2019. Com o aparecimento das FRBR, o conceito de obra torna-se fundamental para mudar o foco no tratamento bibliográfico dos fundos documentais. A obra é a entidade de nível mais elevado e as expressões, manifestações e itens são tratados com relação hierárquica com esta obra. Apresentamos a evolução deste conceito ao longo da história da biblioteconomia. Segue-se a apresentação do aparecimento das FRBR, RDA e BIBFRAME e os conceitos de obra nestes documentos/projetos.
Psicanálise, Política e Verdade
Authors: Ab'Sáber Tales
Published: June 2020

Nesta entrevista, o psicanalista e professor Tales Ab’Sáber reflete sobre a disputa pela ‘verdade’ histórica e as formas como diferentes sujeitos e para diferentes fins dela se apropriam, mobilizando-a para fins políticos eleitorais. Inicialmente, aborda um desses usos, discutindo o revisionismo histórico e sua relação com o fascismo. Em seguida, apresenta as contribuições que campos científicos e reflexivos como a Psicanálise podem fornecer para lidarmos com o atual contexto político brasileiro, em que o revisionismo e o fascismo gracejam no modus-operandi da extrema-direita antidemocrática, violenta, que põe em marcha um discurso de ódio, tal como ele e dois outros colegas tão bem retrataram no documentário Intervenção: amor não quer dizer grande coisa (2017), produzido por eles a partir de vídeos na web que circularam em 2016, ano do golpe, em que representantes dessa extrema-direita convocavam a população para pedir nas ruas “uma intervenção militar” imediata.
Mudanças políticas e eleições na América Latina
Authors: Kourliandsky Jean-Jacques
Published: June 2020

Nesta entrevista, o cientista social e especialista em política internacional Jean-Jacques Kourliandsky avalia o cenário político atual da América Latina. Embora na grande maioria dos países latino-americanos, nas últimas décadas, a democracia tenha demonstrado um funcionamento adequado através da conquista dos direitos eleitorais, se observa atualmente um refluxo quanto a esses direitos e ganha força ideias conservadoras e de extrema-direita, que flertam com o autoritarismo. Em resposta ao tema do evento “Discurso e (pós)verdade. Efeitos de real e sentidos da convicção”, o pesquisador também relaciona a esse refluxo político a propagação e circulação de inverdades.
América do Sul: discurso político, língua, emoções e verdade
Authors: Arnoux Elvira
Published: June 2020

Nesta entrevista, Elvira Arnoux, estudiosa de discursos sobre a língua, fundadora do campo designado por Glotopolítica, apresenta um panorama sociopolítico dos projetos de integração sul-americana e do papel das língua(s) nesse contexto, assim como aborda o tema de sua conferência no V Colóquio Internacional de Análise do Discurso - CIAD acerca das mudanças retóricas na produção do discurso político em tempos de pós-verdade, regidos pela força das emoções e das crenças subjetivas.
Determinación del tamaño del genoma de Gmelina arborea Roxb. utilizando citometría de flujo
Authors: Yaya Lancheros Mary Luz , Terán Wilson
Published: June 2020

La melina es una especie forestal con una alta calidad maderable y de importancia económica para diferentes países tropicales como Colombia. No obstante, existe poca información acerca de su genética, lo cual es pertinente en programas de mejoramiento.

Con el fin de determinar el tamaño del genoma de Gmelina arborea (valor C), se obtuvieron suspensiones nucleares a partir de hojas, las cuales se analizaron mediante citometría de flujo. Para la obtención de suspensiones acuosas de núcleos, se evaluaron cuatro buffers de extracción, de los cuales, el buffer LB01 produjo poblaciones nucleares intactas y con mayor homogeneidad. Se analizaron tres especies vegetales como posibles estándares para la determinación del valor C; utilizando tomate como estándar referente, se obtuvo un valor C para melina de 467 Mpb. Este es el primer reporte relacionado con la estimación del valor C en melina, por lo que se genera así información importante para incrementar el conocimiento relacionado con esta especie.
Evaluación agronómica de caucho natural asociado con tres coberturas vegetales en la altillanura
Authors: García Ibonne Aydee , Garzón Pedro Alberto , Méndez  Tibambre Maria Elizabeth , González Peranquive Carlos Alberto , Cardozo García Carlos Fernando , Peraza Arias Andrés Ricardo , Aristizábal  Gutiérrez Fabio Ancizar
Published: June 2020

Se evaluó el efecto de las coberturas Mucuna bracteata, Desmodium sp. y Pueraria phaseoloides en el crecimiento y su influencia en el estado fitosanitario de un cultivo de caucho natural de dos años de edad en la altillanura colombiana. En condiciones de libre exposición se establecieron tratamientos por cobertura con tres repeticiones y tres réplicas con un control. Las variables respuestas fueron perímetro y la altura total del árbol; se realizaron muestreos del follaje de las coberturas para identificar y cuantificar hongos presentes. Adicionalmente, se hicieron inoculaciones de Colletotrichum gloesporioides en las tres coberturas en condiciones semicontroladas. Se encontró que las tres coberturas generan un leve aumento en la materia orgánica del suelo y favorecen el desarrollo de los árboles. Los hongos más frecuentemente aislados correspondieron a Cladosporium sp., E. sorgui y Fusarium sp. Las inoculaciones mostraron que las tres coberturas son susceptibles a C. gloesporiodes.
Penetration of Dutch Colonial Power Against the Sultanate of Jambi, 1615-1904
Authors: Purnomo Budi
Published: June 2020

The arrival of the Dutch in Jambi gave the impression of almost coincidence because Jambi was not familiar and not a large sultanate in Sumatra compared to Aceh. Even Jambi as a relatively small and unimportant kingdom in the 19th century. However, during the colonial era, some penetrations made to the Sultanate of Jambi. This study examines several factors that caused resistance from the rulers and local people of Jambi against the Dutch colonial power. By using a historical method that emphasized on the secondary sources, this study identifies those factors to make penetration. It shows that economic factors in which the Dutch monopoly trading system is not acceptable to the rulers and local people. It is detrimental and contrary to freedom of trade. Meanwhile, colonial expansion is contrary to the ethical principles they profess. In addition, the failure of the Jambi sultanate had the weakness of their political institutions in facing Dutch colonial penetration. The weakness of their political institutions is influenced by the poor main foundation of the empire and the values of the royal tradition.
Policy Implementation of Lantamal VIII Manado in Handling Transnational Crimes in the North Sulawesi Marine Border
Authors: Handayani Dian , Kuntanaka Wavin Nuha , Rahman Abdul
Published: June 2020

This study aims to identify the policy of Main Naval Base VIII (Lantamal VIII) Manado to handle transnational crimes in the Manado sea border, North Sulawesi. It is implemented in order to support Indonesia's maritime security which contains communication, resources, disposition, and bureaucratic structure. This study uses a qualitative approach with a case study. Data collection using interviews and documentation while examining the data’s validity using triangulation. The argument of this study is the communication made by Lantamal VIII Manado which represents the relation of Indonesia and the Philippines, while coordination between the competent agencies in the waters of North Sulawesi requires good synergy. Nevertheless, there are several problems encountered by Lantamal VIII Manado, namely the lack of personnel and defence equipment. The disposition aspect has been going well according to the command mechanism. In addition, from the bureaucratic structure, Lantamal VIII Manado has a clear division of regional work.
Improvement of yield and yield stability in safflower using multivariate, parametric and non-parametric methods under different irrigation treatments and planting date
Authors: GOLKAR Pooran , RAHMATABADI Nasrin , MIRMOHAMMADY MAIBODY Seyyed Ali Mohammad
Published: June 2020

Development of superior genotypes with high adaptability to different environments is considered as one of the most important goals in safflower breeding programs. In this study, ten parametric and six non-parametric measures along with the additive main effects and the relevant multiplicative interaction (AMMI) model were used to evaluate genotype by environment interaction (GE) in 15 safflower genotypes across 12 test environments ) combination of year, planting date and moisture conditions) during growing seasons in 2016 and 2017. AMMI analysis revealed significant differences among the genotypes and their GE interactions. The different stability statistics were substantiated by rank correlation coefficient. Rank-correlation coefficients revealed positive and significant correlations between mean seed yield and superiority index (r = 0.99**), and significant and negative correlation with bi, R2, Dij and non- parametric measures (NPi(2), NPi(3) and NPi(4)). Based on most stability parameters, the Mex.295 genotype (G10) was found to be the most stable for seed yield. IL.111 genotype (G9) recorded the highest mean yielding genotype regarded as the most favorable safflower genotype. In conclusion, both stability and seed yield should be simultaneously considered to exploit useful effects of G × E interactions in safflower breeding programs.
Genotype and within-pod bean position microenvironment effect on seed choice for raising cocoa (Theobroma cacao L.) seedlings
Authors: ADEWALE Daniel B. , NDUKA Beatrice A.
Published: June 2020

The probable role of within-pod microenvironment on seed sizes, seedling vigour and biomass yield of four cocoa genotypes was investigated for two years. The respective main, sub and sub-sub plots in the split-split plot experimental design were years, genotypes and within-pod bean positions. Data were taken on cocoa bean length, width and thickness after each pod was opened. Four weekly periodic data were obtained for plant height (PH), stem girth (SG) and number of leaves (NOL); root and shoot biomass yield were also recorded. Analysis of variance revealed significant (p ≤ 0.05) bean position, genotypes, years and some interaction on the studied traits. Means of the levels of the three factors differed significantly (p ≤ 0.05). Proximal, middle and distal positions were distinct within-pod microenvironments. The pod middle cavity housed the longest, widest and heaviest beans. Trend analysis of the growing sequences of NOL, PH and SG by the four genotypes differed with bean locations. For bean length, GGE biplot respectively identified CRIN Tc1, CRIN Tc2 and CRIN Tc3 as the best genotype for middle, proximal and the distal positions. The intra-locular space within the pod enhanced differential seed development and maturation; this was evident in the seedling vigour.
Modeling the chemical properties of sesame oil under the influence of pulsed electric field using the artificial neural networks
Authors: ABDOLLAHI Amir , SHAFAFI ZENOOZIAN Masoud , SAEIDIASL Mohammad Reza , ARMIN Mohammad , BEIGBABAEI Adel
Published: June 2020

In this study, PEF pretreatment was used to improve the efficiency of screw press method on the properties of extracted sesame seeds oil. Sesame seeds were treated at different PEF intensities (250, 3250 and 6250 Vcm-1) and pulse numbers (10, 30 and 50). Then, the oil was extracted using a screw press at 33 rpm. Some physicochemical properties of the obtained oil including oil extraction efficiency, acidity index, determination of total phenolic compounds and activity of the inhibition of the DPPH free radical were evaluated. The results showed that the oil extraction efficiency initially increased at first but it showed reduction during PEF pretreatment at higher intensities. Increase in the applied PEF intensity and pulse number lead to an increase in the acidity and total phenolic compounds. While the oxidative stability of the oil reduced at the more intensive PEF conditions. However, the antioxidant activity was firstly increased and then decreased during PEF pretreatment. In addition, artificial neural network model was used to predict the effect of different PEF pretreatment conditions on the physicochemical properties of the extracted oil. The best model was the feed forward neural network with sigmoid hyperbolic tangent conduction function, Levenberg – Marquardt training function with 5-6-2 topology.
Combinative breeding for large seeds in soybean
Authors: NAYDENOVA Galina , RADKOVA Mariana , IANTCHEVA Anelia
Published: June 2020

Technological qualities of the seeds, including their mass, play an important role in the purposeful use of soybean for food production. The purpose of this study is to determine the potential of specific crosses and recombinant lines in the combinative breeding of high yielding large-seeded soybean varieties. During the period of 2018-2019 the F3 and F4 hybride generations of crosses with participation of the ultra-early mature and large-seeded cultivar Romantica were studied. Data were used to evaluate: presence and extent of positive transgressive forms by absolute seed mass in F3 family crosses; genotypic diversity and additive variance at specific crosses; the effectiveness of selection of the trait large seed in F3. According to the results, transgressive selection can be successfully used to reach the goal large seeds in soybean. The efficiency of selection of transgressive forms in F3 generation is high. The genetic potential to combine a high specific mass of seeds with a high yield of seeds per plant has been established for the Romantica cross with the Bulgarian standard variety Srebrina. Recombinant lines suitable for intensive selection for the trait lage seed were obtained from the ‘Romantica’ x ‘Oria’ combination. The ‘Saikai 20’ x ‘Romantica’ cross possess a very high degree of transgressive segregations.
Analysis of practices in childbirth and postpartum hospital care
Authors: Moura Nivea Alane dos Santos , Holanda Viviane Rolim de , Albuquerque Geyslane Pereira Melo de , Castro José Flávio de Lima , Silva Hemelly Raially de Lira , Rocha Elizama Paula Gomes da
Published: June 2020

Objective: to analyze practices in childbirth and postpartum hospital care. Methods: cross-sectional study, conducted with 335 mothers in a reference maternity hospital. A form was used based on the indicators of the Bologna index and guidelines for childbirth and puerperium assistance. Data were analyzed using descriptive and inferential statistics (chi-square, binomial and Clopper-Pearson tests), with p<0.05 being significant. Results: it was observed that 77.9% of the puerperal women considered professional assistance satisfactory. The presence of the doula (p=0.037) and breastfeeding in the first hour of life (p=0.032) had a significant relation with the evaluation of women. The Bologna index evaluation obtained an average of 2.6. Conclusion: there was a higher frequency of intermediate and inadequate practices in childbirth and postpartum care.