bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of different organic manures on the growth and yield of marigold (Tagetes erecta L.) plants
Authors: Halder R K , Gupto S D , Antu A S , Fariha M A , Deb J , Rahman M K
Published: November 2023

A pot experiment was conducted during rabi season in the year 2021-22 under net house condition of the Department of Soil, Water and Environment, University of Dhaka to evaluate the influence of different organic manures on the growth and yield contributing the characteristics of marigold. Seven types of organic manures, viz. Alo, Supermill, Mazim, Vermicompost, ACI, Kazi and Poultry manures were applied singly at the rate of 5 ton ha-1. The tallest plant of marigold (60 cm) found with Supermill, the maximum leaf number (367 plant-1) with Poultry manure, leaf area (6.56 cm2 plant-1), leaf area index (0.017), total fresh weight (15.55 g plant-1) and total dry weight (4.78 g plant-1) of marigold plants were recorded with Mazim organic manure.  The highest number of branches (78 plant-1), flowers (11 plant-1), diameter (2.80 cm), fresh weight (1.90 g plant-1) and dry weight (0.54 g plant-1) were recorded in ACI organic manure. The upper limit length (8.0 cm) of root and the length of shoot (51.30 cm) were recorded in Supermill. The highest root-shoot ratio (0.22) was recorded in Kazi organic manure. The standard range of number of flower’s was 6 to 11 plant-1 with the treatments without using synthetic fertilizer or any toxic pest control substance. The maximum number of flower (11 plant-1) obtained with ACI. The findings indicated the clear possibilities of growing safe and environment friendly marigold flower in context of Bangladesh. The study revealed that all the sources of organic materials enhanced the growth and yield component of marigold. The study also generated a new information as guide line for future research target. The organic sources may be arranged according to the production of number of marigold flower: ACI>Poultry litter> Mazim>Supermill >Alo>Kazi. Further investigation is needed for future research interest.
Biodivers. Conserv. Bioresour. Manag. 2023, 9(2): 39-48
Diversity and seasonal variation of endophytic fungi associated with bark, stem and leaf of agar plant (Aquilaria malaccensis Lam.)
Authors: Shamsi S , Zafrin M
Published: November 2023

The diversity of endophytic fungi was isolated from the bark, stem and leaf of agar plant in  monsoon and winter seasons at different locations of Dhaka and Habiganj districts. A total of 25 fungal isolates were found in monsoon and 22 in winter season. The highest diversity value was found in the bark of location 2 in monsoon according to Shannon diversity index and in the stem of location 1 in winter according to Simpson diversity index. The lowest value was found in the leaf and stem of location 1 and 4, respectively. The evenness of endophytic fungi was highest in the stem of location 1 and lowest in leaf in monsoon based on Shannon evenness index. The maximum species richness was recorded in the bark of location 2 (Margalef’s index) and in the stem of location 1 in monsoon (Menhinick’s index), and the minimum value recorded in the bark of location 4 in monsoon season.
Biodivers. Conserv. Bioresour. Manag. 2023, 9(2): 65-74
Temporal variation, habitat heterogeneity and anthropogenic stressors influencing wildlife communities in an oxbow shaped wetland of lower Ganges floodplain, Bangladesh
Authors: Jaman M F , Alam M M , Rabbe M F , Shome A R
Published: November 2023

Marjat baor is an Ecologically Critical Area located at the lower Ganges floodplain of Bangladesh. A yearlong study wildlife status, community structure and seasonal effect was made following direct field observation in the Marjat baor. A total of 186 vertebrate wildlife species (14 amphibians, 21 reptiles, 131 birds and 19 mammals) were recorded with 9402 individuals. Wetland habitat specialist species were abundant in the community where, Dendrocygna javanica was at the top (5.85%). Herpetofauna showed more uneven distribution than the other animal groups. Due to the richness of migratory birds, seasonal variation showed the highest number of unique species in winter season. A significant difference observed between the community structure of human-dominant and non-dominant landscapes in the ANOSIM test (R = 0.146, p <0.021) and NMDs plot. Floating plant and homestead forest around the baor held the maximum wildlife species. Species richness (F=11.334, p=0.0009) and abundance (F=68, p= 0.0021) differed significantly among the five microhabitats of the study area. The presence of eight threatened wildlife species was noticed in the study area. Anthropogenic stressors causes existential crisis for wildlife. It is revealed that, the community-based conservation may be helpful for conserving the wildlife species in the study area. This study may play a significant role in taking future conservation initiatives.
Biodivers. Conserv. Bioresour. Manag. 2023, 9(2): 83-98
Utilizing net traps to manage pyralid insect population in pond ecosystems: investigating seasonal abundance and their association with duckweeds
Authors: Chowdhury S F N , Parven N , Mahmud M , Kamal S , Belal S I , Begum S
Published: November 2023

A one-year (May to April) study was done about the seasonal abundance of pyralid insect (Synclita occidentalis: Pyralidae), its association with the duckweed (Spirodela sp.), and the effectiveness of emergent trap as a control measure of pyralid insect in mini ponds ecosystem. The adult insects were non-feeding and selected duckweeds for oviposition and larval development. The larvae of different instars were used duckweed fronds as a trophic source (food). For this, the insect attains pest status in its larval stage. The duckweed production is highly hampered due to the attack of this pyralid insect in pond ecosystem. During experiment, two seasonal peaks were noted, one in summer and another in autumn (larvae and adults). The highest relative seasonal abundance of the adults was recorded in June (0.2) and larvae was in August (0.23). The lowest abundance of the adults and larvae was found 0.001 and 0.01, respectively during winter season. In this experiment, it was found that larvae used duckweed fronds as food in maximum 18.86 ± 0.86 and minimum 13.33 ± 0.70. The larva also built protective cases in duckweed fronds. The highest length of the larval cases was 27.07 ± 1.7 mm and width was 14.8 ± 1.75 mm. The larval feeding habit and case-making adaptability give this insect pest status. From the experiment, it was also found that the length and width of the larval cases greatly varied in different seasons and not positively correlated (P > 0.005). The total seasonal abundance of larval cases was lower in treatment ponds (54) than control (103); and not varied significantly (P > 0.005) between the experimental ponds. In addition, the net trap of adult’s emergent had an important role in suppressing pyralid pest population especially in summer. This situation indicated that it might be a key contribution as a control planning during the peak season of pyralid pest outbreak for the management of duckweed in aquatic ecosystems.
Biodivers. Conserv. Bioresour. Manag. 2023, 9(2): 99-108
Socio-economic Factors Responsible for Delayed Presentation of ROP in a Tertiary Neonatal Care Unit in Bangladesh
Authors: Rahman KM Mizanur , Rashid - , Afsana - , Sumiya - , Asma - , Nag Dipak
Published: November 2023

Purpose: To evaluate the socio-economic factors responsible for delayed presentation of ROP in a tertiary neonatal care unit in Bangladesh.
Methods: This observational study was conducted on fifty babies, who were presented delay at screening were purposively selected for the study at Dhaka Shishu Hospital, National Institute of Ophthalmology & Hospital. Study period was 12 months and data collection was done by face to face interview from legal guardians with pre designed questionnaire. Information regarding gestational age, birth weight, condition of health at birth,parents education level and economic condition were obtained by face to face interview from parents. They were also asked whether the baby was advised for screening or not. Screening was done by indirect ophthalmoscopy by using 20D condensing lens.
Results: Among the 50 babies, prevalence of ROP was 66.0% (95% CI: 52.87-79.13). Mean gestational age was 29.10(±1.5) weeks and mean birth weight was 1250(±0.24) gm. After taking account of all possible confounders, we found that place of residence of the parents is associated (p=0.011) as well as adviced for screening is marginaly assocated (p= 0.05) with delayed presentation of ROP for screening.
Conclusion: There are many risk factors for delayed presentation of ROP at screening. Among the factors palce of residence (rural) and advice for screening are found to be significant. Further study regarding this issue is necessary to explore all other factors and formulate plans to overcome them.
J.Natl.Inst.Ophthalmol.2023;6(1): 9-15
Association of Fasting Serum Lipid Level with Diabetic Retinopathy
Authors: Raihan Mohammad Hussain , Rashid Md Shoeb Ur , Morshed Sumon Shahrior , Dipa Mossammat , Akter Nasima , Shuchi Tarzeen Khadiza
Published: November 2023

Background: Diabetic eye disease is now one of the major causes of blindness in the world. Elevated serum lipids have been speculated to cause or exacerbate diabetic retinopathy by several mechanisms.
Objectives: To observe the relationship of serum lipids with diabetic retinopathy.
Methods: This cross sectional observational study was carried out in the Department of Ophthalmology, Combined Military Hospital Dhaka, from July 2016 to December 2016. A total of 150 patients were selected for the study and divided into three groups. Group I comprises 50 patients with different stages of retinopathy. Group II comprises 50 diabetic patients without retinopathy, and group III comprises 50 non diabetic healthy control people.
Results: The age range was 27 to 70 years; Male and female ratio was 1.54:1. The mean duration of diabetes in group I was 9.82 ± 4.04 years and 8.38 ± 3.39 years in group II. Measuring Fasting lipid profile in between group I and group II and between group I and III were statistically significant (p< 0.001).
Conclusion: Patients with diabetic retinopathy have been found to have a close association with elevated serum lipid levels.
J.Natl.Inst.Ophthalmol.2023;6(1): 16-20
A influência do aleitamento materno exclusivo em recém nascidos pré-termo e no seu desenvolvimento
Authors: Machado Débora Rios , Silva Maria Claudia da
Published: November 2023

A amamentação é essencial para o crescimento e desenvolvimento da criança. Ela abrange muito mais do que apenas o ato de alimentar, o impacto que ele tem na recuperação de pré termos é notório. O presente estudo teve como objetivo correlacionar o aleitamento materno exclusivo com o desenvolvimento de recém nascidos prematuros, a amamentação de forma exclusiva beneficia na prevenção de doenças e desenvolvimento psicomotor, na prevenção da obesidade infantil entre outros. O leite materno é cheio de constituintes que beneficiam a criança em todos os aspectos. Essa pesquisa será realizada através de uma revisão de literatura, será feita uma seleção de artigos relacionados com o tema e foi considerado como critério de inclusão os artigos, que abordam o aleitamento materno, seus benefícios para a recuperação de prematuros, seus benefícios para o desenvolvimento do durante a sua primeira infância, estudos que relacionam a obesidade infantil com o aleitamento materno e pontos importantes sobre o aleitamento exclusivo, complementar e propriedades do leite materno. Foi encontrado que mais de 60% das mães não realizam AME pelo tempo ideal e da forma indicada, muitas vezes por conta do leite que secou ou parou de descer, mas também pela falta de tempo devido a licença maternidade e fatores externos. Conclui-se que o aleitamento materno de forma exclusiva auxilia na recuperação de recém nascidos pré termo, ajuda no desenvolvimento e crescimento adequado da criança e gera um impacto positivo nos padrões alimentares e no funcionamento dos sistemas do corpo humano
Nutrição na prevenção e tratamento da sarcopenia no idoso
Authors: Bianco Elisângela Aparecida Duarte Waltrick , Capelari Renata Freitas , Bello Sergio Ricardo de Brito , Pazello Camila Tedeschi , Zarpellon Raquel Simone Maccarini , Venturelli Amanda Caroline , Silva Roxane Wirschum
Published: November 2023

A sarcopenia é caracterizada pela redução da massa e da força muscular. Trata-se de um problema de saúde pública que atinge idosos, afetando de forma progressiva e significativa a qualidade e a expectativa de vida dos mesmos. Diante das complicações associadas a sarcopenia, o objetivo dessa revisão integrativa foi caracterizar a fisiopatologia da doença, bem como identificar a conduta nutricional destinada à sua prevenção e tratamento. Para a elaboração da presente revisão integrativa, foram selecionados 34 artigos científicos em língua inglesa e portuguesa através das principais bases de dados: Google Acadêmico e Medical Literature Analysis and Retrievel System Online (Medline). Os resultados demonstraram que a prevenção e o tratamento da sarcopenia são pautados na oferta adequada de proteínas, prática de alimentação mediterrânea, suplementação de whey protein, vitamina D, ômega 3, leucina, HMB e creatina. Outrossim, recomenda-se a prática de atividade física de modo a promover estimulação regular do tecido muscular.
Efeitos do exercício físico para a melhora na composição corporal e comportamental de crianças com transtorno do espectro autista
Authors: Silva Gabriela Artriclino da , Tavares Vanessa Santos , Pinto Aluísio Avelino
Published: November 2023

No mundo é crescente os casos de crianças com TEA, podemos afirmar que hoje já possuímos milhões de indivíduos com esse transtorno. A educação física oferece as crianças com TEA formas de se expressar e consequentemente benefícios para saúde psicomotora, social e cardiovascular. Esta pesquisa teve como objetivo abordar o tema Transtorno do Espectro Autista (TEA), destacando seus sintomas, a importância do diagnóstico precoce e a crescente incidência. Também enfatiza a necessidade de políticas públicas para a prevenção e tratamento. O estudo propõe uma revisão narrativa sobre os efeitos do exercício em crianças com TEA, abordando a metodologia utilizada na pesquisa, que incluiu a busca e análise de 84 artigos, resultando em 6 relevantes para o tema. Os resultados mostram que o exercício físico bem orientado demonstrou ser uma ferramenta valiosa para melhorar a qualidade de vida das crianças com TEA, promovendo melhorias na composição corporal, no comportamento e interação social.
Mark Catesby, Cromwell Mortimer and Philosophical Transactions of the Royal Society (1730–1748): summarizing Catesby's The natural history of Carolina, Florida and the Bahama islands
Authors: Nelson E. Charles
Published: November 2023

An autograph manuscript written after late October 1747 by Mark Catesby, now in the collections of the University of Virginia, Charlottesville, USA, reveals that he was the author of a summary of the final (eleventh) part of his own book, The natural history of Carolina, Florida and the Bahama islands (1729–1747). The summary was read to the Royal Society by Cromwell Mortimer in February 1748 and was then published under Mortimer's name in the Philosophical Transactions of the Royal Society. Mortimer only lightly edited Catesby's manuscript and added an encomium. In his summary, Catesby took the opportunity, several months after the publication of the final part (“Appendix”) of his two-volume book, to enlarge on a few details.
Wooden barrels for transporting and preserving natural history specimens in the eighteenth century
Authors: Sechrist Guy M.
Published: November 2023

When transporting specimens, both living and preserved, naturalists often took great care when deciding how best to ship them. One of the most important shipping methods was in wooden barrels. In the eighteenth century, many naturalists, including Joseph Banks, John Ellis, and René Antoine Ferchault de Réaumur, advocated the use of, or used, barrels to transport specimens when long voyages often caused specimens to become damaged or destroyed. This paper will investigate the use of wooden barrels by naturalists and detail how such a ubiquitous object proved to be exceptionally important in the history of natural history.
Prometheus on Perelandra: The Inversion of the Satanic Hero in C.S. Lewis’s Perelandra
Authors: Fayard Nathan
Published: November 2023

Approaching the character of Satan in A Preface to Paradise Lost, C.S. Lewis asserted that the Romantics’ admiration for Milton’s angelic rebel as a heroic figure was misplaced. It is a passing reference, but the comment revealed Lewis’s discomfort with the concept of the romantic hero. Two years later, he would continue his investigation of this archetype with his publication of Perelandra. While the way Lewis reworked facets of Miltonic’s Paradise Lost in his extra-terrestrial Garden of Eden have been well studied, the obvious sources for Lewis’s work loom so large in its scholarship that the similar reimagining of Romantic concepts and character types in which he engaged has received little attention. Yet the presence of Romantic echoes among all of the medieval allusions is quite telling. Lewis seems to make particular use of Shelly’s Prometheus Unbound, his favourite poem, in much the same way he does Paradise Lost, adapting that which he loved while ‘correcting’ that which he felt went wrong. This explores this recasting of Romantic concepts and observe Lewis’s efforts to bring the Byronic hero in line with the Christian cosmology of the Ransom trilogy, trying to paint a picture of authentically realized humanity.
I numerali nell’antica Cina: un laboratorio alla scoperta dei sistemi di numerazione
Authors: Brunero Anna Maria
Published: November 2023

Stimolare l’esplorazione dei contenuti matematici è un’attività quanto mai affascinante e allo stesso modo complessa per i docenti della scuola primaria. Questa sperimentazione svolta in una classe quarta concerne un possibile percorso in continuità verticale, trattandosi del riadattamento di una attività sperimentata nella scuola secondaria di primo grado, focalizzando l’attenzione sul laboratorio di matematica come base per l’esplorazione dei contenuti da parte degli alunni. Attraverso strategie di valutazione formativa e per mezzo della discussione matematica, gli allievi si sono confrontati con il sistema di numerazione cinese, mettendo in gioco non solo competenze in ambito matematico, ma in un’ottica di interdisciplinarità, anche in ambito storico. Partendo, infatti, dall’esplorazione del triangolo di Tartaglia-Pascal, contenuto in un antico libro di testo di matematica cinese, gli allievi hanno potuto sviluppare competenze matematiche nel campo dei numeri in linea con un’educazione alla cittadinanza attiva e consapevole.
«Fare il maestro è un lavoro impegnativo!»
Authors: Cataldi Spinola Sara
Published: November 2023

Il progetto di natura interdisciplinare qui presentato è incentrato su un’esperienza di comunicazione fra classi di ordini diversi della scuola dell’obbligo e di apprendimento collaborativo in matematica. Gli allievi di due classi prime della scuola media di Minusio hanno assunto il ruolo di docenti: hanno preparato un itinerario sui triangoli, costituito da alcuni video didattici di introduzione all’attività e dalle rispettive schede di accompagnamento, da sottoporre ai bambini di due classi terze elementari del locarnese; hanno gestito le videochiamate e i lavori di gruppo con i bambini; hanno risposto alle loro curiosità, e infine hanno corretto i loro elaborati. Ad attività conclusa, i ragazzi di scuola media hanno ideato una serie di giochi atti a consolidare gli apprendimenti dei bambini e hanno preparato dei rapporti di sintesi, insieme ai rispettivi docenti di italiano, nei quali hanno esposto, in modalità diverse, il loro vissuto personale e quanto hanno appreso sulla comunicazione e sulla professione docente.
Un paese da scoprire attraverso il gioco
Authors: Martinetti Pamela
Published: November 2023

L’itinerario didattico presentato in questo articolo è stato realizzato in una scuola dell’infanzia del Canton Ticino, approcciando differenti contesti di apprendimento, tra cui i più rilevanti sono lo studio d’ambiente e l’area matematica. Il focus del percorso sono i giochi, in particolare i giochi di una volta, a cui si è arrivati attraverso una serie di fasi di ricerca, di lavoro e di condivisione. Il lavoro mette in luce le competenze matematiche (e non solo) che i bambini hanno sviluppato a partire dalla scoperta, dalla riproduzione e dall’analisi dei giochi. Il percorso ha attivato anche competenze legate alla comprensione e alla produzione di testi descrittivi e regolativi, arricchiti e supportati da sequenze di immagini. Per comprenderne e spiegarne il funzionamento logico, i bambini hanno descritto i giochi svolti e ne hanno inventati di nuovi, creando le regole in forma iconica e scritta.L’itinerario ha permesso di effettuare un passaggio dinamico dal gioco giocato alla condivisione e stesura delle regole e viceversa dalle istruzioni alla realizzazione del gioco.
İstanbul İlindekı̇ Üniversite Öğrencilerinin Kadına İlişkin “Namus” Anlayışı ile İlgili Tutumlarının ve İlişkili Faktörlerin Araştırılması
Authors: DOĞAN Muzaffer Berna , ÇAVUŞ SOLMAZ Yasemin , ÖZ⁹ Burcu , ERDOĞAN Fatime , ÖZDOĞAN Hatice
Published: November 2023

Öz: Bu çalışmada bir toplumun kültürel ve sosyal yapısının değişmesinde ve gelişmesinde rol

oynayan en önemli dinamiklerinden biri olan üniversite öğrencilerinin, kadına ilişkin namus ile

ilgili tutumlarının ve ilişkili faktörlerin incelenmesi amaçlanmıştır. Araştırma tanımlayıcıkesitsel

tiptedir. 200 üniversite öğrencisi araştırmanın örneklemini oluşturmuştur. Çalışma

verileri, öğrencilerin tanıtıcı özelliklerini içeren Kişisel Bilgi Formu ve Kadına İlişkin Namus

Anlayışı Tutum Ölçeği” (KİNATÖ) ile toplanmıştır. Öğrencilerin yaş ortalaması 20,98±1,80,

%69,5’i (n=139) kadın, %30,5’i (n=61) erkek, %62’si (n=124) sağlık ile ilgili bölümlerde

okumaktadır. Genel olarak erkek öğrencilerin, imam hatip lisesinden mezun olmuş, sayısal ile

ilgili bölümlerde okuyan, annesi okur-yazar olmayan, köyde doğan, babası okur-yazar

olmayan, Güneydoğu ve Doğu Anadolu bölgesinde doğan öğrencilerin namus ile ilgili

geleneksel bir bakış açısında sahip olduğu görülmüştür. Bu çalışmada ailenin, cinsiyetin, kırsal

bölgede doğmanın ve yaşamanın, eğitimin namus algısı üzerinde etkili olduğu görülmektedir.

Tüm eğitim aşamalarında, sosyal medya ve iletişim araçlarında, vaaz ve hutbelerde toplumsal

cinsiyet rolleri, kadın-erkek eşitliği, hukuki düzenlemeler ile ilgili bilgilendirmelerin

gerçekleştirilmesi sağlanabilir. Konunun kök nedenlerinin ve önlemlerin belirlenmesi

açısından farklı sosyal çevreye sahip geniş kitlelerle gerçekleştirilecek projelerin, araştırmaların

gerçekleştirilmesi desteklenmelidir.
CLINICAL DIAGNOSTIC CRITERIA AND COMPLEX THERAPY TELOGENE ALOPECIA IN WOMEN
Authors:   Donetsk National Medical University, Ayzyatulov R.
Published: November 2023

Objective. Increase the effectiveness of complex therapy for patients with telogen alopecia with simultaneous use of the drug «Volvit tablets» (biotin 5 mg) inside and «Volvit intensive care shampoo» with biotin externally. Materials and methods. Patients with telogen alopecia, aged 22 to 40 years, who had complaints and a history of the disease (time of onset of increased hair loss, connection of baldness with stress, medication, viral infection, etc.) were under observation. The main diagnostic measures included: pull test, dermatoscopy, trichoscopy, trichogram, laboratory tests (general blood test, general urine test, biochemical blood test; basic trace elements and vitamins, thyroid gland research), scalp biopsy indicated. Consultations with an endocrinologist, psychotherapist, hematologist and other specialists were scheduled. Results and discussion. On the basis of the analysis of literary sources and own clinical and laboratory studies, a complex therapy of diffuse telogen alopecia was developed with the simultaneous appointment of the drug «Volvit tablets» (biotin 5 mg) and «Volvit intensive care shampoo» with biotin, which has a dual effect (treatment from the inside and cosmetic care behind the hair and scalp from the outside). The diagnosis of diffuse telogen alopecia was established on the basis of the clinical picture of the disease and laboratory diagnostic data. Clinical symptoms in patients with telogen alopecia are manifested by uniform, intense hair loss over the entire head, which is noticed after washing the head and combing, when a lot of hair that has fallen out remains. After examining the patient, an individual treatment plan was drawn up, taking into account the identified factors of the disease and accompanying pathology. One of the most common causes of hair loss is an insufficient amount of biotin in the body, and the causes of a decrease in the amount of biotin in the body are stressful situations, an unbalanced diet with an insufficient amount of biotin in products, intestinal dysbacteriosis, diseases of internal organs, disorders of the endocrine system, transferred viral diseases, taking antibiotics and other. Taking into account the above, in the complex therapy of patients with diffuse telogen alopecia, the drug «Volvit tablets» (biotin 5 mg) inside 5 mg once a day and «Volvit intensive care shampoo with biotin» were prescribed at the same time, as a result, good therapeutic results were achieved. Conclusions. Complex therapy of diffuse telogen alopecia with the simultaneous appointment of the drug «Volvit tablets» (biotin 5 mg) internally and «Volvit intensive care shampoo» with biotin externally helps to stop hair loss, restores the hair follicles to their normal function, is expedient in view of effectiveness and safety and can to be recommended for wide implementation in the practical work of doctors
MODERN METHODS OF TREATMENT OF ACTINIC KERATOSIS (LITERATURE REVIEW)
Authors:   Odesa National Medical University, Severhina Yu. V.
Published: November 2023

The subject of the work is to study modern methods of treatment of actinic keratosis (AK) and compare their effectiveness. Materials and methods. 34 international studies on the treatment of AK after 2018 were analyzed. The inclusion criteria for the review were studies with proven efficacy in the treatment of AK. Exclusion criteria were review articles with proven effectiveness of treatment methods. Results and discussions. Due to the increase in cases of AK and its neoplastic transformation (PCC), this problem remains relevant and requires increased monitoring of modern treatment methods. There are several treatment options for AK, both alone and in combination. The main therapeutic tasks in the management of patients with AK include the elimination of clinical and subclinical manifestations of the disease, prevention of transformation into PCC, and reduction of the number of relapses. Both hardware (surgical, cryosurgical, laser, photodynamic (PDT)) and applied (5-FU, imiquimod, diclofenac, tirbanibulin) treatment methods have been proven effective. Conclusions. AK is a fairly common precancerous skin disease, which increases the urgency of the problem in the development of effective treatment methods. Based on the conducted scientific screening, it was concluded that there are various methods of treating AK, with different percentages of positive dynamics and absence of relapses. Combined methods of treatment, which included the hardware method of treatment with the subsequent use of application methods, showed the greatest effectiveness.
Penguatan Nasionalisme Millenial Dalam Politik : Studi Kasus Kader Sekolah Penggerak Partisipatif Badan Pengawas Pemilu Republik Indonesia
Authors: Inggar Saputra  , Firdaus Firdaus
Published: November 2023

Abstract: As the year 2024 approaches, which is often referred to as the political year, the atmosphere of Indonesian politics is believed to be heating up. Hate speech, fake news hate speech, fake news, identity politics and money politics are threats in giving birth to elections with integrity. To achieve victory, politicians have the potential to utilize all means to win voters, including young or millennial voters. Generation Millennials are the generation born between 1980 and 2000. They are characterized as creative, connected to social media and have high self-confidence. high self- confidence. If the destructive potential of political battles hit their unstable emotional maturity, it will certainly have a negative impact on the neglect of morality, ethics and to the neglect of morality, ethics and the value of civility in millennial life. For this reason, participatory activist school cadres are needed to strengthen nationalism and form millennials. strengthen nationalism and form smart, critical and active millennials in facing political turbulence in the era of political in facing political turbulence in the post truth era in the 2024 elections in the 2024 election. This research uses a qualitative descriptive research method descriptive qualitative research method. Data collection techniques using literature studies, observation, in-depth interviews and documentation. The result of the research explained how the participatory activist cadre school was able to provide participants with an understanding of the situation of democracy, national politics national politics and how to strengthen nationalism that is appropriate in facing the developing political conditions. Strengthening nationalism especially in terms of character education through the values of morality, ethics and political civility, both physical actions and the use of both physical actions and utilization of social media in supporting this. Social media utilization in supporting this. The conclusion of the research is participatory activist cadre schools can form a basic understanding of supervision and preventive action against potential destructive threats in the 2024 elections.
A Cytomegalovirus (CMV) Case Study to Promote Interprofessional Learning (IPL) Between Audiology and Biomedical Science Students in Higher Education
Authors: Bashir Amreen , Pallett Ross , Rana Karan Singh , Hussain Saira
Published: November 2023

Modern and effective patient care requires specialist healthcare professionals working together. Interprofessional learning (IPL) seeks to provide opportunities for different healthcare disciplines to learn with, from and about each other. This study focused on the delivery and evaluation of a cytomegalovirus (CMV) case study workshop to facilitate IPL between two Health and Care Professions Council (HCPC) regulated courses: Biomedical Science and Audiology. The 2 h online workshop consisted of 1) defining the roles, responsibilities and skills of the two healthcare professions, 2) the structure of the Biomedical Science and Audiology departments, 3) routes to HCPC registration, 4) core curriculum of both degree programmes and 5) interpreting interdisciplinary data related to a CMV patient case. The workshop was interactive, with the virtual learning environment promoting peer discussions and the use of online polling. Student responses were collected through an online questionnaire. A total of 108 respondents completed a post-event survey and Mann-Whitney U tests revealed there were no significant differences in the responses between the two student cohorts in response to each of the survey statements (p > 0.05). A total of 82.4% of students agreed that they need to know the role of other healthcare professionals for their future practice, whilst 84.2% agreed that the CMV case study was a good format to facilitate effective IPL. A total of 93.5% of respondents recognised the importance of both professions in diagnosing a patient with CMV. Thematic analysis identified four common themes, including appreciation of shared roles, recognition of similarities in registration pathways, working together to provide holistic patient care and the role of clinicians in the patient journey. This novel collaboration between Biomedical Science and Audiology facilitated effective IPL whilst meeting the interprofessional education HCPC requirements. Collaborative working is an essential component of delivering effective patient care and allied healthcare degrees need to provide opportunities within their curriculum to foster this. We hope this study encourages other higher education institutes to expand and develop their current IPL activities to include a broader spectrum of healthcare courses.
Exploring local communities’ perceptions of protected area authorities: a case study from Khlong Lan National Park and Mae Wong National Park in Thailand
Authors: Phoonjampa Rungnapa , Srirattanaporn Surasak , Phumanee Worrapan , Pierrefeu Capucine , Singh Rohit , Ong Elliott James
Published: November 2023

Rangers and local communities play a critical role in enforcing conservation in and around Protected Areas (PAs), yet, their role as planetary health workers and the their relationship dynamics has long been overlooked. This study assesses the relationship between communities and PA authorities in 39 villages adjacent to two high conservation value National Parks in Thailand. Using the responses of 200 participants gathered through a Likert-type survey questionnaire, we analyzed community perception of PA authorities using Ordinal Logistic Regression models. Results indicate good community-ranger relations in the study area. Specifically, regular communication and community involvement in decision-making significantly impact trust and respect towards PA authorities. The models further reveal that while education levels influence trust, a culture of respect for authority figures remains deeply rooted in local communities, highlighting the importance of good PA authorities’ engagement with communities. The results suggest that capacity building for field staff, in particular in social skills and collaboration with local communities, has the potential to improve the relation between communities and rangers. As global efforts intensify to achieve target 3 of the Post-2020 Global Biodiversity Framework, this research offers valuable insights into fostering respectful and trusting relations between communities and PA authorities.
Safety and effects of a home-based Tai Chi exercise rehabilitation program in patients with chronic heart failure: study protocol for a randomized controlled trial
Authors: Jiao Qian , Meng Chao , He Haoqiang , Li Shanshan , Xu Fan , Cui Weilu , Lou Yuqing , Li Zining , Ma Jing , Sun Di , Wu Huidong , Li Haixia
Published: November 2023

Introduction

Chronic heart failure (CHF), as the final stage of the progression of many cardiovascular disorders, is one of the main causes of hospitalization and death in the elderly and has a substantial impact on patients' quality of life (QOL). Exercise-based cardiac rehabilitation (CR) has been shown to considerably enhance QOL and prognosis. Given the barriers to center-based CR faced by most developing countries in the form of expensive instruments, the development of home-based CR is necessary. Tai Chi, as an instrument-free exercise, has been shown to be successful in treating elderly CHF individuals. Fu Yang, as one of the academic concept of Traditional Chinese Medicine (TCM), believes that the fundamental pathogenesis of CHF is the gradual decline of Yang, and emphasizes the restoration of Yang physiological function in the treatment process. Therefore, we develope a home-based Tai Chi exercise rehabilitation program called Fu Yang Tai Chi (FYTC) for elderly CHF patients by combining the Fu Yang Theory of TCM with the CR theory. The objective of this study is to evaluate the effectiveness, acceptability, and safety of the program.

Methods and analysis

We suggest conducting a parallel randomized controlled clinical trial with open label. Eighty CHF elderly participants will be randomly assigned in a 1:1 ratio to the FYTC rehabilitation program group or the moderate-intensity aerobic walking control group. Eligible participants will engage in either three sessions weekly of FYTC or walking exercise for 12 weeks. The primary outcome is the relative change in 6 min walk distance (6MWD). The secondary outcomes are the plasma levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP), QOL, left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDd), self-rating anxiety scale (SAS) and depression scale (SDS), exercise skills, and noninvasive hemodynamic monitoring. Throughout the trial, adverse events will be recorded for safety evaluation. Researchers who are blinded to the treatment allocation will analyze the data.

Ethics and dissemination

This research was authorized by the Guang'anmen Hospital Ethics Committee of the Chinese Academy of Medical Sciences (2022-141-KY). Our findings will be shared online and in academic conferences as well as in peer-reviewed journals.

Trial registration number

ChiCTR2200063511.
Multicenter registry and test bed for extended outpatient hemodynamic monitoring: the hemodynamic frontiers in heart failure (HF2) initiative
Authors: Heywood J. Thomas , Munshi Kartik , Jordan Timothy , Muse Evan , Fudim Marat , Sauer Andrew J. , McDermott Margaret , Shah Hirak , Bhimaraj Arvind , Khedraki Rola , Robinson Monique R. , McCann Patrick , Volz Elizabeth , Guha Ashrith , Jonsson Orvar , Bhatt Kunjan A. , Bennett Mosi K. , Benjamin Terrie Ann , Guglin Maya , Abraham Jacob
Published: November 2023

Background

Hemodynamic Frontiers in Heart Failure (HF2) is a multicenter academic research consortium comprised of 14 US institutions with mature remote monitoring programs for ambulatory patients with heart failure (HF). The consortium developed a retrospective and prospective registry of patients implanted with a wireless pulmonary artery pressure (PAP) sensor.

Goals/aims

HF2 registry collects demographic, clinical, laboratory, echocardiographic (ECHO), and hemodynamic data from patients with PAP sensors. The aims of HF2 are to advance understanding of HF and to accelerate development of novel diagnostic and therapeutic innovations.

Methods

HF2 includes adult patients implanted with a PAP sensor as per FDA indications (New York Heart Association (NYHA) Class III HF functional class with a prior hospitalization, or patients with NYHA Class II or brain natriuretic peptide (BNP) elevation without hospitalization) at a HF2 member site between 1/1/19 to present. HF2 registry is maintained at University of Kansas Medical Center (KUMC). The registry was approved by the institutional review board (IRB) at all participating institutions with required data use agreements. Institutions report data into the electronic registry database using REDCap, housed at KUMC.

Results

This initial data set includes 254 patients implanted from the start of 2019 until May 2023. At time of device implant, the cohort average age is 73 years old, 59.8% are male, 72% have NYHA Class III HF, 40% have left ventricular ejection fraction (LVEF) < 40%, 35% have LVEF > 50%, mean BNP is 560 pg/ml, mean N-Terminal pro-BNP (NTproBNP) is 5,490 pg/ml, mean creatinine is 1.65 mg/dl. Average baseline hemodynamics at device implant are right atrial pressure (RAP) of 11 mmHg, pulmonary artery systolic pressure (PASP) of 47 mmHg, pulmonary artery diastolic pressure (PADP) 21 mmHg, mean pulmonary artery pressure (mPAP) of 20 mmHg, pulmonary capillary wedge pressure (PCWP) of 19 mmHg, cardiac output (CO) of 5.3 L/min, and cardiac index (CI) of 2.5 L/min/m2.

Conclusion

A real-world registry of patients implanted with a PAP sensor enables long-term evaluation of hemodynamic and clinic outcomes in highly-phenotyped ambulatory HF patients, and creates a unique opportunity to validate and test novel diagnostic and therapeutic approaches to HF.
The subject matters for the professional vision of classroom management: an exploratory study with biology and mathematics expert teachers
Authors: Stahnke Rebekka , Friesen Marita
Published: November 2023

Teacher professional vision of classroom management is one crucial aspect of teacher expertise that has so far been studied without considering the role of teachers’ subjects. However, subject teaching is characterized by typical settings and activities that might require different classroom management strategies. This small-scale explorative study investigates whether twenty expert teachers from two secondary school subjects (biology and mathematics) differ in their professional vision of classroom management. Using video clips of two settings as stimuli, teachers’ eye-tracking data and retrospective think-aloud data were recorded. Think-aloud data were investigated with quantitative content analysis and epistemic network analysis. Expert teachers’ visual attention, their noticing of classroom management events, and their knowledge-based reasoning were compared for both groups. Results reveal subject-specific aspects of expert teachers’ professional vision of classroom management in terms of events noticed and their reasoning about these events. Expert biology teachers were more concerned with suggesting alternative classroom management strategies, particularly strategies addressing aspects to consider when planning activities such as providing structure or preparing the classroom. In contrast, mathematics teachers were more evaluative in their analysis of events and focused more on behavioral management or ensuring students’ engagement in the moment.
Thyroid dysfunction and risk of cutaneous malignant melanoma: a bidirectional two-sample Mendelian randomization study
Authors: Dong Hua , Pan Lei , Shen Yanhui , Xu Qinxuan , Hu Jinyu , Hu Zhiwei , Fei Yuchang
Published: November 2023

Background

Epidemiologic and observational data have found a risk association between thyroid dysfunction and cutaneous malignant melanoma (CMM), however, the cause and direction of these effects are yet unknown. By using a bidirectional two-sample Mendelian randomization (MR) methodology, we hoped to further investigate the causal link between thyroid dysfunction and CMM in this work.

Methods

A genome-wide association study (GWAS) of 9,851,867 single nucleotide polymorphisms (SNPs) in a European population was used to develop genetic tools for thyroid dysfunction. Hypothyroidism was linked to 22,687 cases and 440,246 controls. For hyperthyroidism, there were 3545 cases and 459,388 controls. A total of 3751 cases and 372016 controls were included in the genetic data for CMM from UK Biobank (http://www.nealelab.is/uk-biobank) (the Dataset: ieu - b - 4969). Among them, inverse variance weighting (IVW) is the main MR Analysis method for causality assessment. MR-Egger method, MR Pleiotropic residual and outlier test (MR-PRESSO), and simple and weighted median (VM) were used to supplement the IVW method. Sensitivity analyses, mainly Cochran’s Q test, leave-one-out analysis, and MR Egger intercept test were performed to assess the robustness of the outcomes.

Results

The two-sample MR Analysis results revealed a negative correlation between genetically predicted hypothyroidism and the probability of CMM (OR=0.987, 95%CI =0.075-0.999, p=0.041). The supplemental MR Analysis did not reveal any statistically significant differences, although the direction of the effect sizes for the other approaches was consistent with the IVW effect sizes. The results of the causal analysis were relatively robust, according to a sensitivity analysis. The risk of CMM was unaffected by hyperthyroidism (p>0.05). No correlation between CMM and thyroid dysfunction was seen in the reverse MR analysis.

Conclusion

Although the magnitude of the causal association is weak and further investigation of the mechanism of this putative causal relationship is required, our findings imply that hypothyroidism may be a protective factor for CMM.
Search strategy and line association analysis of cascading failure accident chain in new energy power systems
Authors: Cheng Xueting , Liu Wenxu , Bao Yueshuang , Liu Xinyuan
Published: November 2023

As the penetration rate of new energy in the power system gradually increases and the complexity of cascading faults increases, it is of great significance for the power system to comprehensively explore the chain of cascading faults in the new energy power system and quickly determine the closely related lines in the cascading faults. In response to the lack of consideration in existing research of the changes in the importance of transmission lines after the introduction of new energy, this paper proposes a cascading failure prediction index that integrates the importance and operational status of transmission lines in new energy power systems and applies it to the search for cascading failures in new energy power systems. First, the development characteristics of cascading faults were analyzed, and the main factors influencing cascading faults were identified: the importance of the transmission line and operating status of the new energy power system. Based on these factors, a prediction index for cascading faults was established, and the accident chain was searched using this index. Then, the FP-growth algorithm was used to analyze the lines in the fault chain concentration, and based on the analysis results, the correlation relationship suitable for the cascading failure lines in the new energy power system was determined. Finally, a simulation was conducted on an IEEE 10 machine 39 node system containing new energy wind turbines, and the results verified the effectiveness of the proposed indicators and strategies.
Empirical study on the impact of digital economy on carbon emission intensity--based on the mediating role of technological innovation
Authors: Yan Xiaoxia , Zhang Yan
Published: November 2023

With the proposal of “Carbon Peak and Carbon Neutrality” goals, China is facing a more serious carbon emissions reduction situation, and how the booming digital economy effectively helps China’s carbon emissions reduction is one of the most urgent things that should be solved. To study the impact of the digital economy on carbon emission intensity, this paper is based on the panel data of 30 provinces in China (excluding Tibet, Hong Kong, Macao, and Taiwan) from 2011 to 2021, and applies the double-fixed effect model and the threshold effect model to study the impact of the digital economy on carbon emission intensity and the mechanism of its action, as well as to analyze the mechanism of the digital economy’s action on carbon emission intensity from the perspective of technological innovation. The results of the study show that: i) The digital economy can reduce the intensity of regional carbon emissions; ii) The carbon emission reduction effect of the digital economy is non-linear, and its carbon emission reduction effect gradually increases with the level of development of the digital economy; iii) In addition to the direct impact of the digital economy on carbon emission intensity, it also has an indirect impact on carbon emissions through technological innovation; iv) There is regional heterogeneity in the carbon emission reduction effect of the digital economy, and the carbon emission reduction effect is more significant in the central and western parts of the country and regions with a high level of human capital development. Based on the conclusions obtained, this paper suggests: i) The rational integration of the digital economy and regional development should be strengthened; ii) Strong provinces in the digital economy should be encouraged to help weaker provinces, to narrow the “digital divide” between provinces; iii) Differentiated development strategies should be formulated in accordance with local conditions, to give full play to the optimal effect of the digital economy in carbon emission reduction.