bluuebunny/crossref_metadata_2025 huggingface dataset:
A good study about early predictive biomarkers in severe retinopathy of prematurity
Authors: Fu Zhaoqin , Luo Chenghan , Shi Zanyang , Cheng Xinru , Lei Mengyuan , Rong Junbo , Cao Wenjun , Zhang Jingdi , Ge Jian , Ding Wenqian , Song Min , Wang Mengmeng , Zhang Luwen , Ren Miaomiao , Gao Linan , Wang Li , Zhang Qian
Published: August 2022

Objective To explore the evaluation value of N-terminal pro-brain natriuretic peptide (NT-proBNP) and cytokines in predicting severe and therapeutic retinopathy of prematurity (ROP).MethodsPremature infants from January 2020 to January 2022 were enrolled in this single-center retrospective study. General characteristics, seven cytokines within 24 hours and NT-proBNP on the 1st, 3rd, 7th and 14th days after birth were collected. Evaluated these risk factors by using univariate Logistic regression and multivariable logistic regression. Receiver operating characteristic curve analysis was used to evaluate the prediction ability. The outcome measures were the occurrence of any stage ROP, severe ROP and therapeutic ROP.Results528 premature infants were involved, 21.4% premature infants (113/528) were diagnosed with ROP, 35.4% (40/113) were diagnosed with severe ROP, 65% (26/40) received intravitreal anti-vascular endothelial growth factor treatment. After adjusting confounding factors, NT-proBNP at day 7 of life (NT-proBNP7) and IL-6 still remained significantly associated with ROP (P < 0.05). For severe ROP, the cut off values for IL-6 and NT-ProBNP7 were respectively 16.28 pg/mL (AUC = 0.830) and 2553ng/L (AUC = 0.846). The AUC value for combining the two indices was 0.919. For therapeutic ROP, the cut off values for IL-6 and NT-ProBNP7 were respectively 18.08 pg/mL (AUC = 0.845) and 4699ng/L (AUC = 0.829). The AUC value for combining the two indices was 0.915.ConclusionsNT-proBNP 7 and IL-6 can be used as early biomarkers for severe and therapeutic ROP. More importantly, two indicators have significantly higher efficacy than individual indicators.
Algebraizations of Propositional Logic And Monadic Logic
Authors: Al-Odhari Adel Mohammed
Published: August 2022

In this paper, we introduce the language systems of propositional logic (LSPL), which involves no variables, and monadic predicate logic(LSMPL), which consists of predicates applied to single variables. We review the validity and dedication related to (LSPL) and (LSMPL) with their properties. After that, we investigate the connection between Boolean algebras with (LSPL) and (LSMPL) to make algebraizations methods out of logic.
Multi-Response Optimization of Skewing Carton Using Taguchi Method with Desirability Function Approach
Authors: Fitria Silfi , Mashuri Muhammad , Ahsan Muhammad
Published: August 2022

Rapid industrial developments have brought the new challenges for quality improvement in industrial competition. Packaging is an integral part of product presentation to attract consumer. Quality and innovation of the packaging are as important as the product itself. One of the quality characteristics of toothpaste carton packaging is skewing, which is measured by the angle and gap skewness of the cardboard. Skewing process optimization is influenced by several factors i.e. glue temperature, glue pressure, height of guide folding, carton varnish concentration, and carton UV intensity. In this research, the angle and gap skewness of the carton is optimized through various set factors experiment. The optimal experimental design is obtained using Taguchi method with desirability function approach. The results show that height of guide folding, glue temperature, and glue pressure contributed significantly to the effect of skewing. The optimum conditions is obtained by applying the 1500C glue temperature setting, 2 bar glue pressure, 8.3 mm guide folding height, 260 Cps carton varnish concentration, and UV intensity with 3 lamps.
Assessment of Preschool Children’s Exposure Levels to Organophosphate and Pyrethroid Pesticide : A Human Biomonitoring Study in Two Turkish Provinces
Authors: GOL Ersin , Cok Ismet , Battal Dilek , Şukuroglu Ayça Aktaş
Published: August 2022

Pesticides are products that were developed for the benefit of humanity. However, now they are one of the critical risk factors threatening the environment, and they create a significant threat to the environmental health of children. Organophosphate (OP) and pyrethroid (PYR) pesticides are widely used in Turkey as well as all over the world. The main focus of this presented study was to analyze the OP and PYR exposure levels in urine samples obtained from 3–6 year old Turkish preschool children who lives in the Ankara (n:132) and Mersin (n:54) provinces. In order to conduct the determination of three non-specific metabolites of PYR insecticides and four non-specific and one specific metabolite of OPs LC-MS/MS quantitative analyses were employed. The non-specific PYR metabolite 3-phenoxybenzoic acid (3-PBA) (87.1%; n = 162) and the specific OP metabolite 3,5,6-Trichloro-2-pyridinol (TCPY) (60.2%; n = 112) were the most frequently detected metabolites in all urine samples. The mean concentrations of 3-PBA and TCPY were 0.38 ± 0.8 and 0.11 ± 0.43 ng/g creatinine, respectively. Although due to the large individual variation no statistically differences were found between 3-PBA (p = 0.9969) and TCPY (p = 0.6558) urine levels in the two provinces, significant exposure differences were determined both between provinces and within the province in terms of gender. Risk assessment strategies performed in light of our findings do not disclose any proof of a possible health problems related to analyzed pesticide exposure in Turkish children.
A Modified Conveyor-belt Algorithm to solve the critical section problem
Authors: Chanda Nilanjan
Published: August 2022

In the domain of Operating System, critical problem and its related concepts play an important role. Process Management is the most vital part for executing various programs required where every process completes for CPU and may use some common variables and changes made to these variables in concurrent processing can produce undesirable results. In this paper, a different type of algorithm is proposed which deals effectively for solving the critical section problem. This algorithm is based on the working of a conveyor belt that a given set of processes shall circulate over the conveyor belt and any process should be able to execute their critical section when it is its turn while the other processes must continue to circulate, waiting for its turn to enter the critical section until all of them are executed.
Nanocrystal-induced Chronic Tubulaonephropathy in Tropical Countries: Diagnosis, Mitigation, and Eradication
Authors: Wimalawansa Sunil J. , Dissanayake Chandra B.
Published: August 2022

In tropical countries, a mysterious tubulointerstitial chronic renal disease (CKD), unrelated to diabetes, hypertension, and immunological causes, manifested over the past four decades. Approximately 25,000 primarily middle-aged male farmers succumb annually to this crystal-tubular nephropathy (CTN). Its cause is hypothesised to arise from agrochemical or heavy metal contamination of food or drinking water. Since no causative factor was identified, this CKD due to crystalline tubular-nephropathy (CKD-CTN) was known as CKD of unknown aetiology (CKDu or CKDmfo). However, current data suggest that it is due to natural causes. Clinical manifestation of CKD-CTN occurs following decades of consumption of high-ionic stagnant groundwater, aided by fluoride. In all affected countries, prolonged annual dry seasons lead to the concentration of ions and minerals in groundwater, making water unpalatable, thus less water consumption. In addition, exposure to hot climatic conditions and daily alcohol intake sustains chronic dehydration. These conditions provide a highly conducive environment—a perfect storm—for calcium phosphate (CaPO4) crystal formation in renal tissues. Recent histological and preliminary electron microscopic data reveal CaPO4 crystals and nano-tubes deposition in kidneys. While CaPO4 nano-minerals are unstable, the presence of fluoride ions stabilises and makes them grow. This new concept paves the path for highly cost-effective, simple solutions to protect peasants and eliminate the disease without embarking on expensive medications or interventions. Chronic dehydration-associated renal crystal formation is preventable by consuming potable water. This straightforward solution of providing drinking water to affected communities prevents chronic dehydration, CKD-CTN-associated renal failure and premature deaths. However, it becomes irreversible once the disease is established beyond CKD stage IIIB. Therefore, eradicating CKD-CTN is through prevention—education and increased water consumption, not by treating end-stage renal disease, expanding dialysis centres and renal transplantation services. The straightforward approaches described here will prevent CKD-CTN and save thousands of lives in affected farming communities.
IMPLEMENTATION OF ACCOUNTING INFORMATION SYSTEM IN BLUD UPT PUSKESMAS PAHANDUT PALANGKA RAYA POST TRANSFER OF STATUS
Authors: Lestari Murdia
Published: August 2022

Accounting information systems are so important. In services (JasPel) the workforce at BLUD UPT Puskesmas Pahandut still often occurs in calculation errors because there is no latest report on the rank of the workforce itself so that the incentives given are not in accordance with what the workforce should get based on their respective ranks or years of service. respectively. The aims of this study are to (1) describe the application of the cash disbursement cycle for labor services at the BLUD UPT Puskesmas Pahandut Palangka Raya, and to (2) describe the impact of changing the status of the BLUD UPT Puskesmas Pahandut Palangka Raya from UPTD to BLUD on the expenditure cycle.

This research is a field research, with a descriptive approach. The method used in this study is a qualitative method. The subjects in this study were the Head of the TU (KASUBAG TU), the BLUD Expenditure Treasurer, financial staff other contract personnel. The data collection techniques were observation, interviews, and documentation which were then analyzed using data collection techniques, data reduction, data presentation, and drawing conclusions.

The result of this research is that the BLUD UPT Puskesmas Pahandut has been able to implement an accounting information system quite well during the status transition. It's just that there are obstacles that often occur and can lead to calculation errors. The impact of the change in status led to adjustments from the puskesmas and their workforce, decreased service incentive income, and the source of funds came from BLUD revenues.

 

Keywords: Implementation; BLUD; Transfer Status
How do we identify flash droughts? A case study in Central European Croplands
Authors: Alencar Pedro Henrique Lima , Paton Eva Nora
Published: August 2022

Many definitions and delineation methods exist for identifying flash droughts (FDs), which are events of rapid and unusual large depletion of root-zone soil moisture, in comparison to average moisture conditions, due to climatic compound conditions over a short period of several weeks. Six FD identification methods were compared to analyse their functioning using data from several experimental cropland sites across Central Europe. Co- and misidentification of the FD time series were assessed using confusion and synchronicity metrics on a local scale. Even though a large degree of synchronicity of individual FD events was observed, some divergence in drought periods was detected, which was related to four intrinsic differences in the underlying FD definitions: (1) type of critical variable; (2) velocity of drought intensification; (3) pre-set threshold values for final depletion and/or (4) minimum length of the duration of FDs. To balance the strengths and weaknesses of those methods that are not based on soil moisture, we suggest using an ensemble approach for event identification, which is validated in this study for the temperate central European region. In doing so, the current unclearly defined sub-types of FDs can be detected, regardless of the different combinations of compound drivers and differences in intensification dynamics. All methods were implemented in an R package and are available as a Shiny app for the public.
Evaluate the effectiveness technology for the treatment of oily wastewater
Authors: Almutairi Meshari
Published: August 2022

This work deals with the treatment of oily wastewater produced from the washing of oil-contaminated soil. Untreated oily wastewater contains toxic compounds that might be mutagenic or carcinogenic as total petroleum hydrocarbon (TPH) and heavy metals. Based on the water quality analysis, the tested samples contained a high concentration of TPH, chemical oxygen demand (COD) and turbidity with an average value of 67,500 mg/l, 48,240 mg/l and 176 (nephelometric turbidity unit, NTU), respectively. Several technologies were used, such as centrifuging, powdered activated carbon (PAC) and sawdust. The mean values of COD values for sawdust, centrifuging and PAC were 41,067, 25,600 and 13,133 mg/l, respectively. The present study indicated that the coagulation/flocculation processes were more efficient by using aluminium sulphate alum, while the preliminary conclusion derived was that the secondary treatment using an aeration system is capable of lowering the COD values as well as increasing the flocculent mass floc well equal to 4,784 mg/l and 0.69 g, respectively. The microbial seed was able to degrade the biosurfactant, which allows the stability of oil emulsion to be broken down and released easily.
Study on treatment of wastewater with low concentration of ammonia-nitrogen by vacuum plate membrane distillation technology
Authors: Wang Yao , Li Tianxiang , Zhu Jing
Published: August 2022

The removal of low concentration ammonia-nitrogen in industrial wastewater is necessary before discharged into the environment. In this study, vacuum plate membrane distillation (VPMD) technology was utilized and operating parameters such as pH, feed temperature, vacuum degree, feed flow and time were investigated. Based on the experimental data, the heat and mass transfer mechanism and mathematic model were studied. The experimental results show that low solution pH was significantly beneficial to ammonia-nitrogen removal but permeate flux was nearly changeless. At pH = 4, a removal rate up to 93.33% was achieved. Ammonia-nitrogen mainly exists with NH4+ ions in acidic solution, so only water molecules pass through the membrane to acquire the water product in the permeate side. Increasing the temperature of the solution was disadvantageous to the ammonia-nitrogen removal due to membrane pores expanding and the mass transfer coefficient of NH3 molecules increasing; therefore a low temperature was chosen if possible. Because vapor pressure of the feed solution increases exponentially with temperature and results in membrane surface pressure difference increases, therefore increasing the temperature enhances the permeate flux. Raising the vacuum degree enhanced ammonia removal rate and permeate flux obviously, a vacuum degree of 0.09 MPa was chosen for the experiment. The effect of feed flow rate on ammonia-nitrogen removal instead of permeate flux is weak, the reason is that the boundary layer wears thin when the feed flow rate is increased, which is conducive to permeate flux increasing. In a two-parameter model of Knudsen diffusion, Poiseuille flow was chosen to demonstrate the heat and mass transfers in the process of VPMD in the study. Based on the experimental values of permeate flux, two parameters CK and CP in the model were calculated using a nonlinear fitting method software, which indicated that the Knudsen diffusion model more than the Poiseuille flow model was suitable. The maximum values of the relative average deviation (RAD) and root mean square difference (RMSD) of experimental and calculated values with model equations of the permeate flux at the different temperature, vacuum degree and feed flow rate were no more than 8.7% and 3.20 kg · (m2 · h)−1, respectively.
A uberização do amor – aplicativos de encontros em cenário tecnoliberal e pandêmico
Authors: Pelúcio Larissa
Published: August 2022

Neste artigo apresento e discuto de forma ensaísta os impactos do neoliberalismo conservador para as relações erótico-amorosas mediadas pelos aplicativos móveis para relacionamentos, os efeitos da crise sanitária da Covid-19 na busca por parcerias e como a dimensão afetivo-sexual encontra paralelos no presente com a esfera do trabalho precarizado de motoristas e entregadores de aplicativos, a chamada uberização do trabalho. Inspirada pelas proposições recentes da socióloga Eva Illouz busco o cruzamento entre capitalismo, afetos e a relação entre sexo e tecnologia, como componentes de uma nova forma de (não) sociabilidade. Assumo que o amor é uma força política que se encontra colonizada pelos discursos reiteradores do amor romântico. Um tipo de amor alicerçado na desigualdade de gênero, no individualismo e no consumo de emoções e produtos.
IDENTIFIKASI KRITERIA LAYAK HUNI PERMUKIMAN DI KOTA MALANG
Authors: Nugroho Fadjar Iman , Setyono Deni Agus , Kurniawan Eddi Basuki
Published: August 2022

Kota Malang dianugerahkan sebagai kota layak huni berdasarkan IAP dalam kajian Most Livable City Index di tahun 2017. Namun, perlu adanya kajian lebih lanjut dalam mengidentifikasi area mana saja yang masuk dalam kategori kelayakhunian tinggi, sedang, dan rendah di Kota Malang berdasarkan indikator fisik yang mengandung nilai spasial. Fokus dari penelitian ini adalah untuk mengidentifikasi dan menilai zona layak huni di Kota Malang. Metode yang digunakan pada penelitian ini adalah analisis skoring dan analisis spasial menggunakan bantuan GIS. Data-data yang digunakan adalah data sekunder dari instansi terkait serta hasil observasi kondisi eksisting Kota Malang.
The confirmatory factor analysis of science creative pedagogy (SCP) model
Authors:   National Child Development Research Centre, Faculty of Human Development, Universiti Pendidikan Sultan Idris, Tanjung Malim, Malaysia, et al. Abdullah
Published: August 2022

Creative pedagogy is an instructional strategy that emphasizes the central importance of creativity in successful learning. Even though creativity among teachers has been extensively studied, the contributing factors in creative pedagogy are still inconclusive. To bridge the gap, a cross-sectional survey has been conducted to develop the Science Creative Pedagogy (SCP) Model by focusing on the elements that potentially support the motivation for implementing SCP. Therefore, the purpose of this study is to assess the validity and reliability of the CSP measurement model developed in Malaysia. A survey was administered to 409 primary school science teachers, covering the six constructs of elements of creative practice, namely knowledge (PG), environment (SEKITAR), teaching aids (BBM), skills (KEM_GURU), science process skills (KPS), and attitudes (SIKAP). The confirmatory factor analysis was performed, and subsequently, the discriminant validity, convergent validity, and reliability of the measurement model were computed. From the findings, the initial model was then modified from five items per construct to three items per construct, resulting in a refined SCP measurement model. Maps of teachers' creative pedagogy will be made using the construct. This will help the teachers' management bodies to set up a better environment for science teacher who wants to use the SCP in their classrooms.
Interventions Including Smart Technology Compared With Face-to-face Physical Activity Interventions in Older Adults: Systematic Review and Meta-analysis
Authors: D'Amore Cassandra , Reid Julie C , Chan Matthew , Fan Samuel , Huang Amanda , Louie Jonathan , Tran Andy , Chauvin Stephanie , Beauchamp Marla K
Published: August 2022

Background

This is a systematic review of randomized controlled trials and a meta-analysis comparing smart technology with face-to-face physical activity (PA) interventions in community-dwelling older adults (mean age 60 years).

Objective

This study aims to determine the effect of interventions including smart technology components compared with face-to-face PA interventions on PA and physical function in older adults. The secondary outcomes are depression, anxiety, and health-related quality of life.

Methods

We searched MEDLINE, Embase, CINAHL, and AMED electronic databases from inception to February 2021. Two independent reviewers screened titles, abstracts, and full texts and performed data extraction and risk of bias assessments using the Cochrane risk of bias tool. The Grading of Recommendations Assessment, Development and Evaluation was used to evaluate the quality of the evidence. We provided a narrative synthesis on all included studies and, where possible, performed meta-analyses for similar outcomes.

Results

This review included 19 studies with a total of 3455 participants. Random effects meta-analyses showed that interventions with smart technology components resulted in improved step count (mean difference 1440 steps, 95% CI 500-2390) and total PA (standardized mean difference 0.17, 95% CI 0.02-0.32) compared with face-to-face alone. There was no difference between groups in terms of the measures of physical function. Smart technology alone did not show significant differences between groups in any outcome. The quality of the evidence was very low based on the Grading of Recommendations Assessment, Development and Evaluation criteria.

Conclusions

Interventions that include smart technology may improve daily step counts by an average of 1440 steps in community-dwelling older adults; however, the quality of the evidence was very low. Future studies are needed to improve the certainty of these results.

Trial Registration

PROSPERO CRD42020135232; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=135232
Increased Online Aggression During COVID-19 Lockdowns: Two-Stage Study of Deep Text Mining and Difference-in-Differences Analysis
Authors: Hsu Jerome Tze-Hou , Tsai Richard Tzong-Han
Published: August 2022

Background

The COVID-19 pandemic caused a critical public health crisis worldwide, and policymakers are using lockdowns to control the virus. However, there has been a noticeable increase in aggressive social behaviors that threaten social stability. Lockdown measures might negatively affect mental health and lead to an increase in aggressive emotions. Discovering the relationship between lockdown and increased aggression is crucial for formulating appropriate policies that address these adverse societal effects. We applied natural language processing (NLP) technology to internet data, so as to investigate the social and emotional impacts of lockdowns.

Objective

This research aimed to understand the relationship between lockdown and increased aggression using NLP technology to analyze the following 3 kinds of aggressive emotions: anger, offensive language, and hate speech, in spatiotemporal ranges of tweets in the United States.

Methods

We conducted a longitudinal internet study of 11,455 Twitter users by analyzing aggressive emotions in 1,281,362 tweets they posted from 2019 to 2020. We selected 3 common aggressive emotions (anger, offensive language, and hate speech) on the internet as the subject of analysis. To detect the emotions in the tweets, we trained a Bidirectional Encoder Representations from Transformers (BERT) model to analyze the percentage of aggressive tweets in every state and every week. Then, we used the difference-in-differences estimation to measure the impact of lockdown status on increasing aggressive tweets. Since most other independent factors that might affect the results, such as seasonal and regional factors, have been ruled out by time and state fixed effects, a significant result in this difference-in-differences analysis can not only indicate a concrete positive correlation but also point to a causal relationship.

Results

In the first 6 months of lockdown in 2020, aggression levels in all users increased compared to the same period in 2019. Notably, users under lockdown demonstrated greater levels of aggression than those not under lockdown. Our difference-in-differences estimation discovered a statistically significant positive correlation between lockdown and increased aggression (anger: P=.002, offensive language: P<.001, hate speech: P=.005). It can be inferred from such results that there exist causal relations.

Conclusions

Understanding the relationship between lockdown and aggression can help policymakers address the personal and societal impacts of lockdown. Applying NLP technology and using big data on social media can provide crucial and timely information for this effort.
A Narrow Definition of Clinical Robustness (Preprint)
Authors: Marshall Jaclyn , Yurkovic Alexandra , Thames Todd , Parekh Ami
Published: August 2022

UNSTRUCTURED

N/A
Impact of seawater and canopy cover on the phyllosphere bacterial community of Rhizophora mucronata leaves
Authors: Asnat Soudjay , Fahimat Said Hassane , Ahmed Allaouia Allaoui Said , Mohamed An-icha , Abdou Nemati Mohamed , Ismail Soifiata Said , Karima Youssouf Abdou , Sailine Raissa , Aladine Boundjadi Hamdane , Mohamed Nadjim Ahmed , Elyamine Ali Mohamed
Published: August 2022

The plant-microorganism interaction is a well-studied topic in the world of science due to the sustainable management of the ecosystems. The phyllosphere remains the habitat of some microorganisms where several interactions take place. In order to assess whether the mangrove leaves can harbor a bacterial population and analyze the abundance in these leaves microbiotas, leaf samples of mangroves species (Rhizophora mucronata) were collected in the mangroves of Ouroveni in East-Mbandjini, Grande-Comoros. Through the 16S rRNA genes sequencing, the results showed that in the different experimental group, 105303, 110873, 124703, 146954 and 112225 OTUs were identified respectively, where the canopy was open (C1), semi-open (C2), completely closed (C3), and where the plants are submerged (S) and non-submerged (NS) in seawater. The identified OTUs was positively correlated with leaves-wax (p < 0.05, r2 = 0.91), nitrogen (r2 = 0.72), phosphorus content (r2 = 0.62) and the factor “seawater” (r2 = 0.93). It was however highly and negatively correlated with the canopy cover (r2 = 0.93). Considering the factor "seawater", the relative abundance of bacteria in the submerged leaves was significantly higher compared to that from the non-submerged plants. By taking into account the factor “canopy cover”, it was revealed that more the canopy cover was open, the less was the relative abundance of bacteria. Thus, the finding of this present study affirm that the leaves of mangroves can be a major habitat to host a large population of bacteria that can be influenced by local abiotic factor.
La cesión de derechos litigiosos
Authors: Prado Puga Arturo
Published: August 2022

It is proposed to analyze the figure of the as-signment and transmission of litigious rights from a completely new point of view: investigating the reasons that justify the regulation that the Chilean legislation has imposed on this institute.Therefore, three aspects of this figure are specially attended. First, the moment since the right in dispute, acquires the character of litigious. Sec-ond, the right recognized to the debitor to release from the assignment. In third place, the way in which the transfer materializes within the litigation. Following, we refer to the regulation of this figure, analyzed from the ethical point of view, pursuing to characterize the scope of the institute and its consequences. And finally, we analyze a catalog of related figures to the central issue of this article which differ in some substan-tial aspects.
Los marcos del discurso en los spots de los candidatos presidenciales en Estados Unidos 2020"
Authors: Chihu Amparán Aquiles , González Lira Alicia
Published: August 2022

Los especialistas se han enfocado en su mayoría, en analizar los spots políticos televisados desde perspectivas cuantitativas. Por lo tanto se ha dejado un vacío en el análisis de la dimensión cualitativa de la imagen y la identidad de los actores políticos. El objetivo de este artículo es contribuir a la construcción de ese modelo teórico-metodológico ausente y realizar un análisis de la imagen política en general y del spot político en particular. La televisión, los nuevos medios electrónicos, las redes sociales, deben ser analizados a través de otras categorías con las cuales se han estudiado los medios impresos. Con esta finalidad, se propone la tipología del framing audiovisual y como instrumento de codificación una tabla en donde en cada spot el candidato es la unidad de análisis, y el framing audiovisual se describe mediante tres marcos: visual, verbal y sonoro.

 

Palabras clave: marco visual, marco sonoro, marco verbal, framing audiovisual, discurso de campaña.
Ampliación en la distribución de Pteronotus mesoamericanus (Smith, 1972) en la República de Panamá
Authors: Guevara Nelson , López Melissa , Juárez Yelissa
Published: August 2022

Por medio de la captura manual y la descripción de características morfológicas y morfométricas, reportamos el registro de dos individuos adultos de Pteronotus mesoamericanus en las instalaciones de la Reserva Mamoní Valley Preserve, el 27 de abril de 2021. Estos registros amplían la distribución conocida para esta especie en el Istmo de Panamá y la región Neotropical.
Datos preliminares de los registros de puma (Puma concolor) y su posible distribución en Honduras
Authors: Portillo-Reyes Héctor , Elvir Valle Fausto
Published: August 2022

El puma (Puma concolor) es el félido con la más amplia distribución en el continente americano. Se encuentra en una variedad de hábitats en todo el rango de su distribución, que va desde el nivel del mar hasta los 5,800 msnm. Actualmente para Honduras se desconoce su distribución y poblaciones con exactitud. Su estado de conservación según la Unión Mundial para la Conservación de la Naturaleza (UICN) es de preocupación menor (LC). Según la propuesta de la lista roja de especies amenazadas para Honduras, el puma se encuentra en peligro (EN), con poblaciones en disminución. Las principales amenazas para esta especie son: la pérdida de hábitat, su cacería y la de sus presas. De acuerdo con los expertos, la cacería de pumas se da en represalia por ataques a ganado vacuno y caballar, así como a especies menores domésticas de corral y mascotas. La persecución de felinos es la segunda amenaza de importancia después de la pérdida de su hábitat por agricultura. En esta investigación modelamos para Honduras su distribución potencial y los resultados muestran de forma preliminar que el puma se encuentra distribuido potencialmente en 40 % del territorio hondureño, sin embargo, más del 50 % de esta distribución potencial está representada por bosques fragmentados y sistemas agropecuarios (pastos y cultivos). Es de suma importancia integrar a todos los actores involucrados en la conservación del puma de manera activa y participativa, desde comunidades locales hasta los ganaderos, además del gremio académico y ONG´S. Es urgente establecer un monitoreo sistemático y sostenible para pumas, que incluyan las áreas protegidas, corredores biológicos, así como sitios no protegidos para verificar, y confirmar su posible distribución, y desplazamiento por el país. La conservación de las poblaciones de pumas en Honduras, dependen en gran medida, de visualizar y definir con precisión su distribución geográfica.
First predatory record on Caluromys derbianus by Boa imperator in Costa Rica
Authors: Zamora-Roda Álvaro A. , Cortés-Suárez Javier Ernesto , Herrera-Martínez Christian G.
Published: August 2022

Documented predation events regarding Caluromys derbianus as prey are scarce in Central America, only a few wildlife and domestic animals have been reported as predators of this mammal. Herein, we document the first predatory event on this marsupial species by Central American Boa (Boa imperator) in Costa Rica. This record contributes to the ecological knowledge and natural history of this medium-sized mammal.
Design and Development of Solar Water Heater to Enhance Thermal Efficiency
Authors: T Somasekhar , P Naveen Kishore , Kishore M.V.
Published: August 2022

Abstract: This project is about development of a solar water heater with increased thermal efficiency using nanofluids as enhancement medium compared to conventional solar water heater which uses water as the working medium to overcome the inadequate heating of water in the seasons like rainy and winter. In this project Al₂O₃-H2O nanofluid is used as working medium, where Al₂O₃ is used as nanoparticle and water is used as base fluid. A nanofluid is a fluid containing nanometer sized particles, called nanoparticles. These fluids are engineered colloidal suspensions of nanoparticles in a base fluid. It also includes analysis at various concentrations of Al₂O₃ to determine the performance of the solar water heater.
PONIENDO BLANCO SOBRE NEGRO: ANÁLISIS QUÍMICOS Y MICROSCÓPICOS SOBRE SEDIMENTOS Y RESTOS HUMANOS DE LA LAGUNA DEL JUNCAL (VALLE DEL RÍO NEGRO, NORPATAGONIA)
Authors: Marien Beguelin , Vasquez Romina C , Serna Alejandro
Published: August 2022

Se presenta un estudio multi enfoque basado en entierros humanos provenientes de Laguna del Juncal, depositados en forma de bochones en las colecciones de dos museos regionales del Alto Valle del Río Negro desde la década de 1970. Los restos presentan la característica coloración oscura que ha dado lugar a numerosas menciones a lo largo de la historia de la arqueología del río Negro. El objetivo de este trabajo es estudiar la coloración de los restos (natural vs. antrópica) y evaluar su cronología. Para ello se presenta una caracterización bioarqueológica, cronológica y tafonómica de los individuos y sus matrices sedimentarias, utilizando análisis químicos y microscópicos. Se excavaron dos individuos, un adulto y otro subadulto, ambos con escaso material cultural asociado y fueron datados en 720 ± 24 y 754 ± 24 años AP respectivamente. La preservación del adulto es entre regular y buena, mientras que el subadulto presentó peor preservación. Mediante microanálisis químicos (MEB) se registró alto contenido de manganeso y hierro en los sedimentos, así como en el material óseo, lo cual explicaría su coloración oscura. Se discuten los resultados en el marco de los conocimientos actuales de los entierros del noreste de Patagonia
Diel metabolic tuning revealed by in situ transcriptome and proteome in a vertically migratory copepod
Authors: Maas Amy , Timmins-Schiffman Emma , Tarrant Ann , Nunn Brook , Park Jea , Blanco-Bercial Leocadio
Published: August 2022

Zooplankton undergo a vertical migration which exposes them to gradients
of light, temperature, oxygen and food availability on a predictable
daily schedule. Anticipating and responding to these environmental
conditions, which independently are known to influence metabolic rates,
likely has an appreciable effect on the delivery of waste products to
the distinctly different daytime (deep) and nighttime (surface)
habitats. Disentangling the co-varying and potentially synergistic
interactions on metabolic rates has proven difficult, despite the
importance of this migration to oceanic biogeochemical cycling. This
study examines the transcriptomic and proteomic profile of the
circumglobal migratory copepod, Pleuromamma xiphias, over the diel
cycle. The transcriptome showed a large number of up-regulated genes
during the middle of the day – the period often considered to be of
lowest metabolic activity. There were proteomic and transcriptomic peaks
in oxidative stress response and muscle proteins after the periods of
migration, suggestive of a physiological consequence of migration. There
were changes in metabolic pathways over time, with increased ammonium
production signals during the evening and chitin synthesis and
degradation pathways during the day. Comparisons of patterns across the
paired datasets suggest that 1) estimates of physiological rates made in
the laboratory in steady state conditions that don’t account for time of
day may not be adequate to predict in situ phenotypes 2) use of ‘omics
datasets to predict organismal phenotypes must be done cautiously as
highly dynamic patterns in the transcriptome and proteome are often
dampened and sometimes asynchronous at the enzyme or organismal level.
Treatment outcomes in childhood acute lymphoblastic leukemia: 40-year experience from a single tertiary center in Thailand
Authors: Chavananon Shevachut , Sripornsawan Pornpun , Songthawee Natsaruth , McNeil Edward , Chotsampancharoen Thirachit
Published: August 2022

Background. Studies on the long-term treatment outcomes of
childhood acute lymphoblastic leukemia (ALL) in resource-limited
countries are scarce. The purpose of this study was to assess the
evolution of survival outcomes of pediatric ALL in a tertiary care
center in Thailand over a 40-year period. Patients and methods.
We retrospectively reviewed the medical records of pediatric patients
who were diagnosed with ALL and treated at our center between June 1979
and December 2019. We classified the patients into 4 study periods
depending on the therapy protocol used to treat the patients (period 1:
1979-1986, period 2: 1987-2005, period 3: 2006-2013, and period 4:
2014-2019). The Kaplan Meier method was used to determine overall and
event-free survival for each group. The log-rank test was used to
identify statistical differences. Results. Over the study
period, 726 patients with ALL were identified, 428 boys (59%) and 298
girls (41%), with a median age at diagnosis of 4.7 years (range:
0.2–15 years). The study periods 1, 2, 3, and 4 had 5-year event-free
survival (EFS) rates of 27.6%, 41.6%, 55.9% and 66.4%, and 5-year
overall survival (OS) rates of 32.8%, 47.8%, 61.5%, and 69.3%,
respectively. From period 1 to period 4, both the EFS and OS rates
increased significantly (p<0.0001). Age, study period, and
white blood cell (WBC) count were all significant prognostic indicators
for survival outcomes. Conclusions. The overall survival of
patients with ALL treated in our center improved significantly over time
from 32.8% in period 1 to 69.3% in period 4.
Whole-Body MRI for cancer surveillance in Ataxia Telangiectasia: A qualitative study of the perspectives of people affected by A-T and their families
Authors: Neves Renata , Perez Blanca De Dios , Tindall Tierney , Fernandez Natasha Schneider , Panek Rafal , Wilne Sophie , Suri Mohnish , Whitehouse William , Jagani Sumit , dandapani madhumita , Dineen Robert , Glazebrook Cris
Published: August 2022

Background/objectives: Ataxia Telangiectasia (A-T) is a complex
inherited disease that is associated with an increased risk of
malignancy. Surveillance guidelines have demonstrated significant health
benefits in other cancer predisposition syndromes (CPS). Evidence-based
guidelines for cancer screening are not currently used in the UK for
people affected by A-T. This study aims to understand how people with
A-T and their parents feel about cancer surveillance using whole-body
MRI to inform the future development of cancer surveillance guidelines.
Design/Methods: We conducted semi-structured interviews of people
affected by A-T. Data were analysed inductively using thematic analysis.
Results: Nine parents of children with A-T and four adults with
A-T were interviewed. Five main themes emerged from the data. All
participants viewed cancer screening for children with A-T as invaluable
and emphasised the perceived value of early detection. The second theme
acknowledged the anxiety associated with cancer and cancer surveillance
and the third theme highlighted the perceived limitations around current
practice, with the responsibility for monitoring falling too strongly on
parents and patients. The fourth theme identified the need for effective
preparation for cancer screening, including clear communication, and the
challenges of MRI screening were recognised in the fifth theme with
specific recommendations made for improving the child’s experience.
Conclusion: This study suggests that stakeholders are positive
about the perceived advantages of a cancer screening programme. Ongoing
support and preparation techniques should be adopted to maximise
adherence and minimise adverse psychosocial outcomes.
Investigation of the Corrosion Fatigue Behavior of AA 7020 Alloy in Seawater
Authors: Yurdgulu Ibrahim , Sadeler Recep , Yilmaz Hasan , Koc Baris
Published: August 2022

The effect of two-step aging treatment on the fatigue behavior of welded
AA 7020 Al. alloy was investigated. For fatigue tests to be carried out
in atmospheric and seawater environments, a plane bending tester at a
stress ratio of R=0 was used. Experiments in the control group were
carried out with non-welded specimens at a strain rate of R= -1 in air.
The gradual heat treatment (two step aging, TSA) significantly improved
the fatigue and corrosion fatigue behavior of welded AA 7020 alloys.
Unwelded specimens showed better fatigue properties than welded ones. In
experiments in a seawater environment, pitting and exfoliation corrosion
occurred on the surface. It was determined that the corrosion pits
reduce the fatigue life of welded and unwelded samples. It was also
observed that the corrosion sensitivity of the welded specimens
increased in the heat affected zone (HAZ) and corrosion fatigue cracking
occurred in these zones.
Do Newly Born Orphan Proteins Resemble Never Born Proteins? A Study using Deep Learning Algorithms
Authors: Liu Jing , Yuan Rongqing , Shao Wei , Wang Jitong , Silman Israel , Sussman Joel
Published: August 2022

Newly Born proteins, devoid of detectable homology to any other
proteins, known as orphan proteins, occur in a single species or within
a taxonomically restricted gene family. They are generated by expression
of novel Open Reading Frames, and appear throughout evolution. We used
the recently developed programs for predicting protein structures,
RoseTTAFold and AlphaFold2, to compare such Newly Born proteins
to random polypeptides generated by shuffling sequences of native
proteins, which have been called ‘ Never Born’ proteins. The two
programs were used to compare the structures of two sets of four
Never Born proteins, one set that had been expressed and shown to
be intrinsically disordered, and a second set that had been shown
experimentally to possess substantial secondary structure. Since the
programs rely to a large extent on multisequence alignment, the models
generated were scored as being of low quality. However, a significant
pattern emerged when the models generated by RoseTTAFold were examined.
Specifically, all four members of Group 1 were shown to be very
extended, as would be expected for intrinsically disordered proteins. In
contrast, all four members of Group 2 appeared to be compact, and
possessed substantial secondary structure. As a further control, both
programs predicted unfolded structures for three well characterized
intrinsically disordered proteins. The two programs were used to predict
the structures of two orphan proteins whose crystal structures have been
solved, both of which display novel folds. RoseTTAFold predicted both
structures very well, whereas AlphaFold2 predicted only one well. The
two programs were used to predict the structures of five orphan proteins
with well-identified biological functions, one of which is predicted to
be intrinsically disordered, and four to be folded. Both programs
displayed the intrinsically disordered protein as an unfolded structure.
RoseTTAFold displayed all four of those predicted to be folded as
compact folded structures, with apparent novel folds, as determined by
Dali and Foldseek. It is plausible that new biological functions may be
implemented by orphan proteins due to their novel folds.
Coupled stochastic systems of Skorokhod type: well-posedness of a mathematical model and its applications
Authors: Thieu Thoa , Muntean Adrian , Melnik Roderick
Published: August 2022

Population dynamics with complex biological interactions, accounting for
uncertainty quantification, are critical for many application areas.
However, due to the complexity of biological systems, the mathematical
formulation of the corresponding problems faces the challenge that the
corresponding stochastic processes should, in most cases, be considered
in bounded domains. We propose a model based on a coupled system of
reflecting Skorokhod-type stochastic differential equations with
jump-like exit from a boundary. The setting describes the population
dynamics of active and passive populations. As main working techniques,
we use compactness methods and Skorokhod’s representation of solutions
to SDEs posed in bounded domains to prove the well-posedness of the
system. This functional setting is a new point of view in the field of
modelling and simulation of population dynamics. We provide the details
of the model, as well as representative numerical examples, and discuss
the applications of a Wilson-Cowan-type system, modelling the dynamics
of two interacting populations of excitatory and inhibitory neurons.
Furthermore, the presence of random input current, reflecting factors
together with Poisson jumps, increases firing activity in neuronal
systems.
Role of terracing in water-balance components of Platycladus orientalis during normal and dry years in the Loess Plateau, China
Authors: Huang Yue , Wei Wei
Published: August 2022

Extensive ecological projects, including terracing engineering and
vegetation rehabilitation, have been implemented in many water-limited
mountains across the world, aiming to combat drought and control water
erosion. Nevertheless, due to the complexities of climate, terracing,
and vegetation types in actuality, knowledge gaps regarding the role of
terracing on water balance remain. Therefore, to better understand the
influence of terraces on water budget in a normal (2015) year and dry
(2016) year, a field experiment was conducted in a typical dry loess
hilly area of China. The effects of adverse grade tableland terraces,
fish-scale pits and the natural slope on water content change were
analyzed on the slope of Platycladus orientalis by the
water-balance technique and equations. The results showed that, compared
with natural slope, terraces had higher water budget benefits both in
dry year (+ 1.08~12.24 mm) and normal water year (+
15.71~27.29 mm), and adverse grade tableland terrace had
the best performance. Although precipitation was the primary factor
affecting water inputs, terraces can significantly increase soil water
content. Evapotranspiration and runoff were the main water loss terms,
but terrace also can help to reduce runoff water loss. Overall,
transformation of terraced fields can optimize the forest structure and
improve the eco-benefits at the slope scale.