bluuebunny/crossref_metadata_2025 huggingface dataset:
Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
Authors: Merella Pierluigi , Talanas Giuseppe , Lorenzoni Giovanni , Denurra Cristiana , Atzori Enrico , Casu Gavino
Published: October 2023

Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO.
Influence of PMMA particle size control on the transmittance of PMMA/tempo-oxidized cellulose composites
Authors: Altarugio Julia P. , Staffa Lucas H. , Carvalho Antonio J. F. , Almeida Juliana M. P.
Published: October 2023

Cellulose is a class of biopolymers that prominently contributes to developing lightweight, eco-friendly, and biodegradable plastics. Among them, nanofibrillated cellulose (NFC) is one of the most interesting due to its mechanical behavior. Mixing it with synthetic plastic such as poly(methyl methacrylate) (PMMA) reduces synthetic polymer usage, agro-industrial residue and develops fiber-reinforced composites. NFC was prepared from residual biomass and oxidized with TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical). Herein, NFC was incorporated (25, 50 and 75 wt%) in a colloidal emulsion of PMMA, with PMMA particle size control (50 and 175 nm). The investigation of this system on the PMMA/NFC transparency was addressed here. FTIR and SEM demonstrated effective incorporation of NFC and interaction with the PMMA. The increment of NFC increased the water contact angle and improved film transparency. Paired with PMMA particle size control, particularly at 50 nm, this favored composite transparency, becoming close to or even greater than pure NFC.

Graphical abstract
Futures contracts as a means of hedging market risks
Authors: Arenas-Falótico Andrés Jerónimo , Scudiero Eliza
Published: October 2023

This academic article examines derivative instruments, their role in financial markets, and the associated risks. Derivatives, such as options, forward contracts, and futures, have gained increasing popularity due to their potential for hedging, market efficiency, and investment opportunities. The article discusses the reasons behind the growth of derivative usage, including economies of scale and the interdependence between futures, spot, and options markets. Additionally, it emphasizes the importance of derivatives in investment decisions, risk reduction, and speculation for companies and investors. The concept of derivatives is defined, highlighting their dependence on the value of underlying assets. The article further explores different types of risks, including systematic and unsystematic risks, and emphasizes the need for risk management strategies in derivatives trading. It also delves into futures contracts, explaining their historical development and the standardized elements they encompass. The roles of different market participants, such as hedgers, speculators, and arbitrageurs, are examined, along with the crucial function of clearing houses in facilitating derivatives transactions. The article concludes by discussing price calculation methods for futures contracts, considering factors such as storage costs, interest rates, and convenience yields. The research methodology involves a theoretical analysis of derivative instruments, their markets, and risks, supplemented by practical examples. Overall, this article provides valuable insights into the theoretical framework surrounding derivatives, enhancing our understanding of their significance in modern financial systems.
Założenia polityki zagranicznej Prawa i Sprawiedliwości wobec Rosji w programie wyborczym partii z 2019 r.
Authors:   Politechnika Koszalińska, Liszkowska Dominika
Published: October 2023

This article presents the main assumptions and attributes of the Law and Justice (PiS) policy towards Russia, included in the party’s 2019 election program – “Poland – a model of the welfare state”. The article aims to answer the following questions: What policy assumptions towards Russia were presented by Law and Justice in its 2019 election program? What elements does PiS’s policy towards this state consist of? What are the features of this policy? What are the reasons for the approach and policy of PiS towards the Russian Federation? the 2019 PiS election program or subject to a qualitative analysis is the source and starting material for showing the main goals, elements and features of PiS’s foreign policy towards Russia.
The importance of the United States in Poland’s military security policy in the context of the war in Ukraine
Authors:   Kazimierz Wielki University in Bydgoszcz, Jureńczyk Łukasz
Published: October 2023

The subject of the article is the importance of the United States in Poland’s military security policy in relation to the war in Ukraine. The article begins with an introduction discussing its main assumptions and a synthetic historical background of the importance of the US for Poland and its security. The main part of the article is divided into two parts, the first one discussing the importance of the US in Poland’s military security policy after the Cold War. The second part is devoted to the change in the importance of the US in this policy in connection with the outbreak of the war in Ukraine and the main factors that determine this change. The aim of the article is to identify and analyze the changes in the importance of the United States in the Polish military security policy as a result of the outbreak of the war in Ukraine in 2022. The main research problem is whether the importance of the US in Poland’s military security policy increased as a result of the war, and if so, because of what main factors? The thesis of the article states that the war in Ukraine increased the importance of the US as the main external guarantor of Poland’s security and defense. This is due to the leading role played by the United States in military support for Ukraine and strengthening NATO’s eastern flank, including Poland, in the absence of leadership from Western European powers. The research included interviews with scientists and analysts from research centers in Washington and New York.
Bezpieczeństwo energetyczne Turcji
Authors:   Baltic Defence College, Olech Aleksander , Potera Natalia ,   Uniwersytet im. Adama Mickiewicza w Poznaniu
Published: October 2023

Türkiye is dependent on imports of energy resources from abroad, but its current economic strategy is based on the diversification of supply sources, which will make it less susceptible to possible manipulation by suppliers. The government’s energy policy focuses on increasing the share of renewable energy resources and domestic energy. Despite the ongoing armed conflict in Ukraine, Türkiye has not given up on energy cooperation with Russia, trying to balance between East and West. The main reason was the Covid-19 pandemic, which forced Ankara to intensify economic and energy contacts with Moscow again. The aim of the article is to present the challenges that Türkiye is currently facing in the sphere of energy security. The authors of the article will try to answer the following research questions: What is the primary objective of Ankara’s economic strategy? Does Türkiye have alternatives to energy cooperation with Russia? The role of Ankara in the NATO Alliance is crucial as well as its position in the international arena. For this reason the research on Türkiye must be carried out.
Aporie zrównoważonego rozwoju
Authors:   Politechnika Łódzka, Zaorski-Sikora Łukasz
Published: October 2023

The article considers the aporias underlying the idea of sustainable development and the 2030 Agenda. The reports made for the Agenda show, on the one hand, that in recent years the number of people living in extreme poverty has significantly decreased, on the other hand, it turns out that the goals of sustainable development are implemented are faster and more effective in developed countries. In other words, we observe that despite the relative improvement in living conditions in the poorest countries of the global South, most of the profits still go to the wealthiest countries of the North, which get richer at the expense of the poor. The author concludes that the aporetic nature of the 2030 Agenda has been unintentionally expressed already in the preamble, where the idea of sustainable development is compared to modern Esperanto, thanks to which the activities of governments and business are to be integrated under the aegis of the United Nations, and notes that the vast majority of vocabulary in Esperanto comes from languages Western European, and the language is always governed by a specific axiology and social structure – it turns out that it is easier for Western countries to find the semantic, syntactic and, above all, pragmatic reality assumed in the Agenda.
Predictive Assessment of the Potential Electric Vehicle Market and the Effects of Reducing Greenhouse Gas Emissions in Russia
Authors:   Siberian Federal University, Kolyan Nelly S. , Plesovskikh Alexander E. ,   Siberian Federal University, Gordeev Roman V. ,   Siberian Federal University
Published: October 2023

In recent decades, the global adoption of alternative fuel vehicles, which may contribute to carbon emission reduction due to the use of alternative energy sources has stirred particular interest. Despite a significant body of scientific literature in Russia about electric vehicle adoption, the approaches used in papers lack quantitative estimates of the Russian market's potential. This paper aims to fill this gap as it provides a long-term electric vehicle market forecast in Russia as well as assesses the environmental effects. The following hypotheses are tested: (1) the Bass model is applicable to predict the long-term electric vehicle diffusion process in Russia; (2) the transition to electric cars will have a significant impact on greenhouse gas emission reduction. The Bass model, a widely used tool for predicting the innovation diffusion process, serves as a methodological base for the research. The long-term forecast of the Russian electric car fleet includes several scenarios. The most realistic scenario suggests that the Russian electric vehicle market is estimated to grow, reaching 5.62 million units by 2060. Furthermore, the environmental effects associated with electric vehicle adoption were identified. Two scenarios for changes in the energy generation structure were taken into consideration. The expected carbon emission reduction is estimated to reach 14.08 million tons in CO2-eq. if an accelerated transition to low-carbon energy sources is implemented, the baseline scenario suggests 12.86 million tons in CO2-eq. carbon emission reduction. The estimates of the transport diffusion in Russia as well as of environmental effects associated with this process form the theoretical value of the study. The practical significance of the study suggests developing electric vehicle demand forecasts that might be utilized while implementing measures to achieve goals stated in the Strategy of Social and Economic Development with a Low Level of Greenhouse Gas Emissions until 2050 in the Russian Federation.
Evaluation of the Effectiveness of Investment Tax Incentives in Russia
Authors:   Financial Research Institute, Pinskaya Milyausha R. , Steshenko Yuliya A. ,   Financial Research Institute, Tsagan-Mandzhieva Kermen N. ,   Financial Research Institute
Published: October 2023

Investment is one of the most important factors determining economic fluctuations in the short term and economic growth in the long term. For this reason, governments in many countries have long been engaged in developing policies aimed at increasing business investment activity, with investment tax incentives being one of the main tools used. Russia currently has many investment-oriented tax incentives, which creates a special need for a comprehensive assessment of their effectiveness. The aim of the study is to develop and test a methodology for assessing the effectiveness of investment tax incentives, with the help of which it is possible to determine whether the benefit brings a positive effect both for the beneficiary and for the state. The hypothesis of the study is that the evaluation of the effectiveness of investment tax incentives can be carried out based on financial and economic data about the company. In this study, we searched for examples of evaluating the effectiveness of investment tax incentives in the context of each company that is the beneficiary of the incentive in the works of foreign scientists and at the state level. It is concluded that in most countries with a high level of assessment of the effectiveness of tax expenditures, such methods are not used. As a result of the study, a methodology for assessing the effectiveness of investment tax incentives was proposed and tested, which involves an analysis of the application of incentives by operating organizations. The methodology focuses on indicators of financial and economic analysis; the assessment is carried out based on indicators determined at the level of the beneficiary and characterizing the effectiveness of the use of these benefits both for the state (fiscal efficiency) and for the taxpayer (economic efficiency). The value of the study is determined by the proposals to improve the analytical system “Effectiveness of Benefits”, already launched in 2022, which is unlike any other in the world. The results of the work are of interest to government agencies and non-profit organizations to diagnose the effect of the use of benefits.
The Influence of Digital Environment Factors on the Development of Entrepreneurial Ecosystems in Russian Regions
Authors:   Amur State University, Yakimova Vilena A. , Pankova Svetlana V. ,   Orenburg State University
Published: October 2023

The relevance of the study of entrepreneurial ecosystems in a digital environment is caused by the presence within specific regions of network relationships between entrepreneurship, business support institutions, scientific and educational organizations, and the state in the context of the transformation of information and technology exchange processes. In the face of the challenges of the digital economy, there is a need to determine the points of growth of regional ecosystems and identify the effects of the impact of transformational factors on the relational components of the ecosystem, which are formed by the new digital environment. The aim of the study is to model the effectiveness of the impact of the digital environment on indicators characterizing the level of development of entrepreneurial ecosystems in the space-time continuum. The research hypothesis is that the factors of the digital environment stimulate the formation of entrepreneurial ecosystems in the region. Methods: we used techniques and methods of clustering, correlation and regression analysis, and space-time modeling. Results: the authors substantiated the composition of the basic components of the model of the regional entrepreneurial ecosystem, formulated the key principles of its functioning, and determined the criteria for its condition. We have selected and structured indicators indicating the impact of the digital environment on the effectiveness of the functioning of entrepreneurial ecosystems. The article contains data on the identification of regions with pronounced signs of the presence of entrepreneurial ecosystems. The authors have established the features of their geographical location. We have compiled models of the impact of digitalization on the criteria indicators of regional business ecosystems. The study determined the positive impact on the profitability growth of the presence of fast-growing companies in the region, the information and computer technology sector, and the size of its state and investment support. The authors have identified a direct dependence of business concentration on information resources, infrastructure, and financial components. We have established the degree of influence of acceleration and incubation platforms, scalable projects in the field of end-to-end technologies and investments in IT projects on the number of fast-growing companies and startups. The results develop the theoretical propositions of regional business ecosystems, criteria for their condition and functioning, and the influence of digitalization factors on their development. The obtained results can be used for the formation and adjustment of programs for the implementation of strategies in the field of digital transformation of the regional economy.
Assessment of the Regions Functioning Based on Production Functions with the Above Cost Factors
Authors:   Tula Branch of the Financial University under the Government of the Russian Federation, Zhukov Roman A. , Plinskaya Maria A. ,   Tula Branch of the Financial University under the Government of the Russian Federation, Manokhin Evgeny V. ,   Tula Branch of the Financial University under the Government of the Russian Federation
Published: October 2023

When modeling the growth of a regional economy by means of production functions, a problem arises of choosing models, factors and methods for adjusting cost characteristics in order to obtain adequate and accurate models, as well as the formation of integral and partial indicators of performance that provide a correct assessment and analysis of the performance of the regions of Russia. Such a problem becomes especially significant if the models are adequate and accurate, and, consequently, the process under study is invariant with respect to the models, factors and calculation methods used. The aim of the study is to estimate the results of the regions' performance on the basis of production functions, provided that the process of changing the volume of GDP by region is invariant with respect to models, factors and methods of bringing them to a comparable form when modeling the growth of the Russia regional economy. The hypothesis of the investigation is the invariance of the process of the change of the volume of GDP by region relative to the models, factors and methods used to bring the cost indicators to a comparable form. The study used data on the CFD regions (2007–2020). As a result, five models were constructed, the factors of which were calculated in five different ways, taking into account both price changes and average annual characteristics. It was determined that partial indicators have similar dynamics. At the same time, statistical tests and the author's methodology for choosing a model that would take into account the priorities of regional development did not allow for identifying the best of them. This allowed us to conclude that the process under study is invariant with respect to the models and correction techniques used. To solve the problem of choosing models for evaluating the regions' performance results, it is proposed that an integral performance indicator should be applied that summarizes the calculation methods used. This would reduce the influence of subjectivity of such a choice. The theoretical significance lies in the possibility of applying the methodology to form integral and partial indicators of performance for arbitrary socio-economic systems. The practical significance of the conducted research lies in the fact that the results obtained can be used to design activities that would be aimed at ensuring the CFD regions' sustainable development.
Sex and gender differences in health and disease. Part I. Evolutionary
Authors: Drapkina O. M. , Kim O. T.
Published: October 2023

Sex affects many aspects of a person's existence, including health. Life expectancy is one of the most telling examples of differences between the sexes. Almost all over the world, women have been found to live longer than men, but the gap in life expectancy varies considerably from country to country. The review discusses the evolutionary mechanisms behind this difference and potential strategies for increasing male life expectancy. Likely processes leading to sex-specific morbidity are also considered.
MYCRUNCHGPT: A LLM ASSISTED FRAMEWORK FOR SCIENTIFIC MACHINE LEARNING
Authors: Kumar Varun , Gleyzer Leonard , Kahana Adar , Shukla Khemraj , Karniadakis George Em
Published: October 2023

Scientific machine learning (SciML) has advanced recently across many different areas in computational science and engineering. The objective is to integrate data and physics seamlessly without the need of employing elaborate and computationally taxing data assimilation schemes. However,
preprocessing, problem formulation, code generation, postprocessing, and analysis are still time-
consuming and may prevent SciML from wide applicability in industrial applications and in digital
twin frameworks. Here, we integrate the various stages of SciML under the umbrella of ChatGPT, to
formulate MyCrunchGPT, which plays the role of a conductor orchestrating the entire workflow of
SciML based on simple prompts by the user. Specifically, we present two examples that demonstrate
the potential use of MyCrunchGPT in optimizing airfoils in aerodynamics, and in obtaining flow
fields in various geometries in interactive mode, with emphasis on the validation stage. To demonstrate the flow of the MyCrunchGPT, and create an infrastructure that can facilitate a broader vision, we built a web app based guided user interface, that includes options for a comprehensive
summary report. The overall objective is to extend MyCrunchGPT to handle diverse problems in computational mechanics, design, optimization and controls, and general scientific computing tasks involved in SciML, hence using it as a research assistant tool but also as an educational tool. While here the examples focus on fluid mechanics, future versions will target solid mechanics and materials science, geophysics, systems biology, and bioinformatics.
A review of the United Nations’ initiatives to promote more sustainable infrastructure
Authors: Morgan Geoffrey
Published: October 2023

Geoffrey Morgan, a chartered civil engineer at the United Nations Office for Project Services, highlights the significant work the UN is doing to help civil engineers learn more about sustainable, resilient and inclusive infrastructure development and how they can incorporate it into their daily work.
Symbolic Capital and Social Space
Authors: Córdoba-Rentería Libardo , Trujillo Milton
Published: October 2023

To identify forms of interaction between the members of the Chocó, Tumaco, Guapi and Buenaventura colonies, understand the relationships among identity, ethnic and racial coexistence in the interaction and highlight some forms of symbolic capital arising from knowledge, history and shared social space in the colonies, we conducted an investigative exercise based on popular education. We turned to three individuals who are representative of the Bonaverense culture—Mary, Flor and Edgardo— whose collective and individual histories will allow us to identify which factors of ethnic and racial identity inherited from the colonial era are the basis for power relations from the past to the present and underlie the identity processes of communities that have been historically subdued and silenced to hear their stories in their own words, expose their ways of seeing the world and value their voices as sources of knowledge
Уточнение влияния конструктивных особенностей контактно-дугогасительной системы модульного автоматического выключателя на его коммутационные характеристики
Authors: Самуилов Дмитрий Владимирович , Антонов Алексей Игоревич , Иванов Иван Петрович , Моисеев Сергей Алексеевич , Трофимов Евгений Юрьевич
Published: October 2023

Введение. Рассмотрено влияние параметров конструкции контактно-дугогасительных систем (КДС) на основные коммутационные характеристики модульных автоматических выключателей.
Методы и результаты. По результатам анализа конструкций образцов типопредставителей модульных автоматических выключателей ведущих мировых производителей выделены особенности их КДС, установлены основные параметры, используемые при их проектировании. В ходе экспериментальных исследований дугогашения уточнены значения критических токов, фактического тока отключения при коротком замыкании, времени и скорости дуги. Использованы осциллограммы токов и напряжений, съемки оптического излучения дуги скоростной камерой.
Заключение. Результаты исследований применены при модернизации выключателей ВМ16 и разработке рекомендаций по проектированию КДС.
Slam to Heal.
Authors: d'Abdon Raphael
Published: October 2023

In termini generali, la slam poetry può essere descritta come poesia competitiva recitata/letta in spazi pubblici da poeti in erba. Nei tornei di slam poetry, i giovani concorrenti affrontano argomenti come intersezionalità, violenza di genere, storia, traumi, ecc. di fronte a folle attente e partecipative, catalizzando la loro attenzione e la loro energia in luoghi carichi di emozioni. Tuttavia, a causa della sua forma problematica e della sua insistenza sulla performance piuttosto che sulla scrittura, la slam poetry è anche uno degli argomenti più controversi all’interno dei dibattiti che si svolgono su temi quali letteratura, società e cultura popolare: da una parte, si trovano i detrattori, che la liquidano frettolosamente, sostenendo che sia una carnevalizzazione della poesia; dall’altra ci sono i praticanti e amanti dello slam, che lo considerano un’espressione artistica innovativa, in gran parte emancipata dalle convenzioni prosodiche e dalle ‘norme’ linguistiche dell’accademia. Utilizzando la poetic inquiry come metodologia di ricerca, questo articolo offre un’analisi comparativa di testi che sostengono entrambi i punti di vista e riassume la loro tesi centrale in found poems. Inoltre, attinge alle teorie della poetry therapy, al fine di arrivare a una posizione di sintesi che sia capace di offrire una visione complessa della slam poetry in Sudafrica e altrove.
Overcoming problematic growth phenotypes in organoids from patients with monogenic GI disease v1
Authors: Bugda Gwilt Katlynn , R. Thiagarajah Jay
Published: October 2023

Patient-derived organoids provide a unique model system to explore disease causing mutations ex vivo. By use of organoids from duodenal or colonic biopsies of pediatric patients with intestinal epithelial disorders, we can directly assay the patient cells to tailor treatment to their unique disease state. The advent of organoid technology from patients with severe intestinal disorders such as either Congenital Diarrhea Enteropathies (CoDE) and Very-Early-Onset Inflammatory Bowel Disease (VEO-IBD) has allowed for rapid advances in the understanding of and the treatment of these monogenic disorders. Still, the expansion of these lines for scalable studies is not trivial, and success rates of expansion are variable between groups, and even lab members within the same group. These protocols have been validated on patients with CoDE or VEO-IBD and age matched control patients. Here, we present our recommended protocols for the cultivation of organoids from pediatric patients with CoDE and VEO-IBD. These protocols have been validated on organoids generated from the duodenum (duodenoids), ileum (ileoids), colon (colonoids) and iPSC derived intestinal colonoids from pediatric healthy donors or donors with CoDE or VEO-IBD1. Using our modified culture media, extended culture times from biopsy preparation and thawing frozen lines, gentle passaging techniques with the incomplete removal of the organoids from the matrigel, and modified monolayer protocols2,3, we have been able to successfully culture and expand several lines for >5 years. The conditions and protocols used here provide a basis for reproducible phenotypes, scaling for larger functional studies on patient lines, and for reproducibility of results between several investigators. We provide a useful starting point and troubleshooting guidelines for optimization of culturing organoids from any patient with novel disease pathology
Barcode Composition by Overlap-Extension PCR v1
Authors: Chu Mathew
Published: October 2023

Traditionally, DNA barcodes are synthesised as random oligonucleotides. However, this leads to uncertainty regarding the ground truth of barcode sequences in the experimental setting. Without reference sequences, it is impossible to determine with absolute confidence whether or not the observed diversity of barcodes is due to errors arising from sequencing itself or various cellular and molecular processes. Here, we propose a modular way to assemble high-diversity libraries of DNA barcodes from units whose individual sequences are known a priori. Barcode units are amplified and then combinatorically spliced in vitro using overlap-extension PCR, yielding products that can be assembled into vectors for downstream applications.
Gene editing of YIPF4 in hESCs V3 v1
Authors: JW Harper , Hickey Kelsey , not provided sharan_swarup
Published: October 2023

This protocol describes the creation of YIPF4 knockout hESCs.
Flow cytometry-based measurement of trafficking of Golgi to the lysosome via autophagy V3 v1
Authors: JW Harper , Hickey Kelsey , not provided sharan_swarup
Published: October 2023

Protocol for flow cytometry-based measurement of Golgi trafficking to lysosomes via autophagy using Keima-YIPF3/4 reporters in HEK293 cells.
Food, Gender, and Social Status in Rural Parts of North-West India: A Case Study of Rajasthan
Authors: Mohan Vikas , Gill Reema
Published: October 2023

The purpose of this research is to investigate the relationship between eating habits, gender roles, and social status in rural areas of North-West India, with a particular emphasis on the part that women play in the production and consumption of food. This study investigates the ways in which cultural and social standards influence food practices and preferences among women and men of different social and economic backgrounds by conducting ethnographic research and in-depth interviews with rural households in different regions of Rajasthan. According to the findings of this research, women's eating behaviours are frequently restricted by gender roles and expectations, which in turn restricts their access to food resources and their ability to make decisions regarding the food that they consume. In addition, it was discovered that social standing and caste play a significant role in shaping food practises and preferences, with households of higher castes typically consuming more expensive and nutritionally dense food items. In its conclusion, the study highlights the necessity of interventions that are culturally appropriate and gender-sensitive. These interventions should address the underlying social and cultural factors that contribute to gender and social disparities in food access and consumption in rural areas of Rajasthan.
Food Waste Mitigation Strategy Hotel X in West Java
Authors: Salsabila Nadine Diaz , Priatini Woro , Hindayani Purna
Published: October 2023

The generation of food waste in hotels is inevitable and the amount is uncertain despite the hotel's preventive measures. Food waste has a negative and detrimental impact on the hotel business because it makes more costs in purchasing and producing food so that a mitigation strategy is needed to minimize food waste generation. The research was conducted at four-star hotel X in West Java. This research aims to produce a prevention strategy to reduce food waste in hotels. The method used was qualitative. Data collection techniques include interviews, observations, and documentation studies. The results showed that the average food waste generated by hotels every day reached 128 kg. With this high number, action is needed to reduce food waste. Strict hotel regulations make food waste management options limited. Therefore, consistency in implementing mitigation strategies and openness and commitment from the hotel to make policies related to food waste are needed.
CLINICAL CASE OF A PATIENT WITH EXTREME HYPERTROPHIC CARDIOMYOPATHY AND RECURRENT IDIOPATHIC TRANSUDATIVE PERICARDIAL EFFUSION
Authors: Dren’ Elena V. , Sogoyan Nerses K. , Lyapina Irina N. , Golubovskaya Daria P. , Pecherina Tamara B. , Barbarash Olga L.
Published: October 2023

Highlights

We report a case of a patient with extreme hypertrophic cardiomyopathy and complex cardiac pathology undergoing heart transplantation. The article will be useful for cardiologists, therapists and cardiovascular surgeons.

 

Abstract

We present a case of a patient with extreme hypertrophic cardiomyopathy, Wolff–Parkinson–White syndrome and nonspecific chronic exudative pericardial effusion with recurrent idiopathic transudative pericardial effusion. This case involves several approaches to treatment – medication and surgery for treating a patient with combined cardiomyopathy and pericardial effusion, which served as a “bridge” for a later change inro radical treatment - orthotopic heart transplantation.
HYPERTENSIVE DISORDERS OF PREGNANCY – MANAGEMENT STRATEGIES IN THE POSTPARTUM PERIOD (LITERATURE REVIEW)
Authors: Rudaeva Elena V. , Kashtalap Vasily V. , Marciyash Alexey A. , Moses Vadim G. , Savchenko Yana A. , Moses Kira B. , Elgina Svetlana I. , Rudaeva Elena G.
Published: October 2023

Highlights

Hypertensive disorders of pregnancy are associated with short- and long-term risks for the mother.

We have identified several key points in the management strategy of this pathology in the postpartum period, which should contribute to the emergence of new directions in the prognosis and treatment modalities of this disease.

 

Abstract

The article presents an analytical review of modern data on the treatment of hypertensive disorders of pregnancy (HDP) in the postpartum period. HDPs lead to maternal morbidity and mortality in developing and poor countries, and in regions with well-developed healthcare systems as well. HDPs can later progress into hypertension and are associated with the risk of coronary artery disease and stroke. Moreover, HDPs increase the likelihood of low-birth-weight babies and preterm births. The incidence of HDP is growing worldwide despite the implemented prevention methods: according to the Global Health Data Exchange, from 1990 to 2019 HDPs` incidence by 10.9% from 16.3 million to 18.08 million people. However, the introduction of universal approaches to prevention of complications made it possible to reduce mortality from HDP in the same period by 30.05%. The risk of hypertensive complications increases significantly in the postpartum period. Modern research confirms this – the likelihood of worsening HDP and the development of complications increases significantly in the first 24–48 hours after childbirth. About one third of cases of eclampsia occur in the postpartum period, of which almost half occur 48 hours after delivery. Stroke in women with HDP occurs in the postpartum period in half of the cases. Arterial hypertension (AH) in the postpartum period often requires an increase in doses of antihypertensive drugs, whereas after 3–6 months, many patients no longer need such therapy. During the first year after childbirth, the risk of progression of AH and the development of complications due to hypertension is increased, and remains so for many years. The feasibility of antihypertensive therapy in HDP today is beyond doubt, however, there are issues that require further study. They are related to the safety of prescribed drugs during lactation, and as a result, in many guidelines, antihypertensive therapy in the postpartum period is prescribed with reservations. Another problem is the relatively small number of RCTs directly assessing the effectiveness of antihypertensive therapy in the postpartum period.
Modal-based analysis of the refrigerated wagon body with different placements of energy refrigeration equipment
Authors: Voron Oleg  A. , Bulavin Yuri  P.
Published: October 2023

Aim: modal analysis of the body of a refrigerated wagon with energy refrigeration equipment in various locations.
Materials and Methods: the problem was solved using the finite element method, and the participation factor was used to analyze the results.
Results: The frequencies and mode shapes of the refrigerated wagon body variants were determined.
Conclusion: The frequency of vibration changes little depending on the body design and lies in the range of 7-5 Hz. The mass of the refrigeration unit does not have a significant impact on the frequency of vibration. The largest displacements occur on the roof of the wagon. At a certain combination of the stiffness of the spring suspension and the mass of the load, resonant phenomena may occur.
Evaluation and ways to reduce uncertainty of greenhouse gas emission and seqestration
Authors: Akhtyamov Rasul G.
Published: October 2023

Background: The transport industry is one of the major sources of greenhouse gas emissions, and is inevitably influenced by the environmental agenda.
Aim: Estimation of the uncertainty and develop ways to reduce uncertainty when accounting for emissions and removals of greenhouse gases.
Methods: The method of analyzing the statistical causes of uncertainty in the measurement and accounting of emissions and removals of greenhouse gases, as well as the analysis of literary sources, suggests ways to reduce uncertainty.
Results: The sources of uncertainty in the implementation of the climate change transport adaptation plan obtained when taking into account emissions or removals of greenhouse gases were identified. At the same time, objectively determined causes of uncertainty associated with shortcomings in the data, models used and analyzed samples, as well as causes of uncertainty based on subjective assumptions, are identified. Of practical significance are the formulated ways to reduce uncertainty, based on improving the conceptualization, improving the model structure, increasing the representativeness of the data, as well as using more accurate measurement methods.
Conclusion: Ways to reduce uncertainty in the implementation of the climate change transport adaptation plan based on subjective parameters are to introduce adaptive management and develop learning as an iterative process, as learning becomes a key component of activity in a changing climate.
On the suitability of medium speed maglev transport systems: an analysis of perceptions in the transportation sector
Authors: Kluehspies Johannes  Oliver , Kircher Roland , Witt Michael , Haenel Simon , Blow Laurence  E.
Published: October 2023

Background: Medium speed maglev transport systems are considered a disruptive innovation. This complicates potential access to the transport market, which is dominated by conventional, traditional transport systems. Can maglev systems compete with them?
Aim: Aimed specifically at transport professionals, the survey analyses current [2023] perceptions of maglev systems for passenger and freight transport. Are medium speed maglev systems suitable for the future of transport from the perspective of transport experts?
Methods: International web survey of five hundred professionals in the transport sector. The focus is on application and suitability. It is not a technical comparison of systems.
Results: Medium-speed maglev systems are considered to be competitive, and in some cases superior, to established transport systems in the same speed range. However, most international experts see the suitability of maglev systems primarily for specific applications, such as passenger transport between airports and city centers, or as a freight transport system for special logistics tasks.
Conclusion: An innovation of maglev systems in well-defined applications seems reasonable and promising from an expert's point of view.
DILEMA ANTARA KRISIS EKONOMI DAN TRADISI: EDUKASI MASYARAKAT DAMPAK PERNIKAHAN DINI DI DESA LUMBANG, KABUPATEN PASURUAN
Authors: Nisa’u Faline Izza , Yuniar Ananda Dwitha , Syah Fahim , Egadiantasari Florica Dwi , Alfita Rizqi Ananda
Published: October 2023

Early marriage is a form of phenomenon that is often found in Lumbang Village, this is motivated by various factors ranging from education, socio-culture, and economy. Efforts are needed to raise public awareness in preventing early marriage for adolescents and parents. Various efforts have also been made by village officials to help suppress early marriages that occur in Lumbang Village. So, this service aims to provide material on understanding the impact of early marriage from the health sector so that people become aware of the importance of health before deciding to get married and can reduce the number of early marriages that occur in Lumbang Village. The results of this field service concluded that most of the participants who attended the socialization still cared about their health, while among those who were married, based on social and economic factors, they were forced to choose early marriage. After this socialization activity, the implementing group monitored and reviewed the level of early marriage in Lumbang Village with marriage data through the Office of Religious Affairs (KUA) administrator.Pernikahan dini menjadi salah satu bentuk fenomena yang banyak ditemui pada Desa Lumbang. Hal tersebut dilatarbelakangi oleh berbagai faktor mulai dari pendidikan, sosial budaya, dan ekonomi. Diperlukan usaha untuk menyadarkan masyarakat dalam mencegah terjadinya pernikahan dini, baik pada remaja dan juga orang tua. Berbagai upaya juga telah dilakukan oleh perangkat desa untuk turut menekan pernikahan dini yang terjadi di Desa Lumbang. Oleh karena itu, pengabdian ini bertujuan untuk memberikan materi pemahaman dampak melakukan pernikahan dini dari bidang kesehatan agar masyarakat menjadi peduli akan pentingnya kesehatan sebelum memutuskan untuk menikah dan dapat menekan angka pernikahan dini yang terjadi di Desa Lumbang. Metode yang dilakukan dalam pengabdian ini yakni menggunakan metode partisipatoris, dimana penulis dapat memperoleh hasil berupa gambaran, arahan, dan respon mitra secara langsung. Hasil dari pengabdian ini menyimpulkan bahwa dari sebagian peserta yang hadir pada sosialisasi masih banyak yang peduli akan kesehatan mereka sementara itu mereka yang sudah menikah didasari karena faktor sosial dan ekonomi sehingga mereka terpaksa memilih menikah dini. Pasca kegiatan sosialisasi ini kelompok pelaksana melakukan monitoring dan meninjau tingkat pernikahan dini di Desa lumbang dengan data pernikahan melalui pengurus di Kantor Urusan Agama (KUA).
Szumatriptán–naproxén-nátrium fix dózisú kombinációja a migrén akut kezelésében – irodalmi áttekintés
Authors: Tajti János , Csáti Anett , Szok Délia
Published: October 2023

A migrén az elsődleges fejfájásbetegségek közé tartozó gyakori megbetegedés, ami nagymértékben károsítja az egyén életminőségét. Gyógyszeres kezelésében akut és megelőző terápiákat különítünk el. Az Európai Fejfájás Társaság és az Európai Neurológiai Akadémia közös terápiás ajánlása alapján rohamterápiában nem kielégítő triptánválasz esetén javasolt triptán és nem szteroid gyulladásgátlók együttes adása. Munkánkban a fix dózisú szumatriptán–naproxén-nátrium (85 mg/500 mg) kombinációjú tabletta használatával kapcsolatos eredményeket (hatásosság, biztonságosság) tekintjük át randomizált klinikai vizsgálatok eredményei alapján. A fix dózisú szumatriptán–naproxén-nátrium kombinált farmakon a placebóhoz és az egyes összetevőkhöz viszonyítva statisztikailag szignifikánsan több migrénes páciensben eredményezett a gyógyszerbevételt követően 2 órával teljes fejfájásmentességet. Eredményesen csökkentette a migrén kísérőtüneteit, úgymint a hányingert, valamint a fény- és hangérzékenységet. A készítménnyel kapcsolatosan észlelt leggyakoribb mellékhatás a hányinger és a szédülésérzés volt, ami arányaiban megegyezett a placebóval. A fix dózisú szumatriptán–naproxénnátrium kombinált tabletta a migrén akut kezelésében hatékony, jól tolerálható és biztonságosan használható farmakon.
Compliance- és betegútvizsgálat betegségmódosító kezelés alatt álló sclerosis multiplexes betegeknél
Authors: Mátyás Klotild , Bobál Tamás , Abonyi Zsolt
Published: October 2023

Háttér és cél – Az epidemiológiai adatok és a kezelt betegek száma alapján felmerül, hogy a magyar sclerosis multiplexes (SM) betegek alacsonyabb számban, illetve kisebb arányban kapnak betegségmódosító kezelést (DMT), mint egyes környező országok SM-betegei. Ennek okát próbáltuk kideríteni. Módszerek – Először a betegek compliance-ét elemeztük a Nemzeti Egészségbiztosítási Alapkezelő (NEAK) anonimizált adatbázisa alapján. A NEAK vénybejelentési adatait 2014. július 1. és 2021. február 28. közötti időszakra vonatkozóan vizsgálva összesen 5441 beteg került be az elemzésbe. A vizsgálat másik részében az SM-betegek betegútjának kvantitatív és kvalitatív felmérését végeztük. Eredmények – A vizsgálatok szerint a magyar SM-betegek compliance-e a nemzetközi SM-terápiás adatokhoz képest is jó, az egyéb neurológiai, illetve más, például cardiovascularis betegségekéhez képest pedig kiemelkedő. Nem mondható ez el a betegek megkérdezése alapján történt betegútelemzés eredményéről. A betegek jelezték, hogy gyakran nehezen férnek hozzá az állami egészségügyi ellátáshoz. Betegútjukat követve kiderült, hogy 3–5 orvosnál (háziorvos, különböző szakorvosok) kellett megjelenniük a diagnózis megszületéséig. Az SM-centrumokról viszont pozitív visszajelzést adtak. Bíznak a gondozó orvosaikban, empatikusnak találják őket, amellett, hogy több időt igényelnének az életmódra vonatkozó kérdések megbeszélésére. Következtetés – Egyes környező országokkal összehasonlítva Magyarországon alacsonyabb a kezelt SM-betegek aránya, ami, mivel a betegek compliance-e megfelelő, a hazai betegútproblémára hívja fel a figyelmet. Az orvoskollégák továbbképzése az SM-specialista neurológusoknak is feladata. Ahogyan a stroke leggyakoribb tüneteit sikerült bevezetni a közgondolkodásba, cél lehet ugyanez az SM-mel kapcsolatban is.
Shock Dependent Exchange Rate Pass-Through - An Analysis for Latin American Countries
Authors: Rossi José Luiz , Costa João Paulo Madureira Horta da
Published: October 2023

This paper investigates the exchange rate pass through considering the source of the shocks that hit the economy. With a Bayesian Global VAR model, the exchange rate pass-through is analyzed for 5 Latin American countries: Brazil, Chile, Colombia, Mexico and Peru. The model is estimated with Bayesian techniques and is identified by sign and zero restrictions. The BGVAR estimation enable us to allow spillover between countries mimicking the real conditions when the shocks hit the economies. Four domestic shocks for each Latin American countries are considered: an exchange rate shock, a risk premium shock, a monetary policy shock and a demand shock. The demand shock has the highest exchange rate pass-through for all the countries and the exchange rate shock has the lowest one. Additionally, two regional shocks are considered: a regional monetary policy shock, an event that all the region rises its interest rate and a regional risk premium shock, where the risk premium rises at the same time. For almost of the countries, the exchange rate pass-through coming from those regional shocks are lower than its domestic counterpart shock. Finally, we investigate two global shocks, an uncertainty shock and a global commodities/demand shock. The uncertainty shock decreases the economic activity and depreciates the exchange rate with a negative exchange rate pass-through in the middle term. The commodities/demand shock increases the economic activity and appreciates the exchange rate passthrough, having a negative or neutral exchange rate pass-through over the time.