bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of defects of enamel with polymorphisms in the vitamin D receptor and parathyroid hormone genes
Authors: Renostro-Souza Amanda , Fonseca-Souza Gabriela , Küchler Erika Calvano , Vasconcelos Katia Regina Felizardo , Feltrin-Souza Juliana , Kirschneck Christian , Matsumoto Mírian Aiko Nakane , Lepri Cesar Penazzo , Oliveira Maria Angelica Hueb de Menezes , Thedei Júnior Geraldo
Published: June 2024

Abstract This cross-sectional study aimed to investigate the association between developmental defects of enamel (DDE) and single nucleotide polymorphisms (SNPs) in the genes encoding the vitamin D receptor (VDR) and parathyroid hormone (PTH). Orthodontic patients receiving treatment at a dental school were selected through convenience sampling. Intra-oral photographs were used to assess DDE, which were classified according to the criteria proposed by Ghanim et al. (2015) by a single calibrated examiner (Kappa>0.80). Enamel hypoplasia, molar-incisor hypomineralization (MIH), hypomimineralized second primary molar (HSPM), and non-MIH/HSPM demarcated opacities were considered for the analysis. Genomic DNA was extracted from buccal cells. The SNPs in VDR (rs7975232) and PHT (rs694, rs6256, and rs307247) were genotyped using real-time polymerase chain reactions (PCR). Statistical analyses were performed using the PLINK software (version 1.03, designed by Shaun Purcell, EUA). Chi-square or Fisher's exact tests were performed at a significance level of 5%. Ninety-one (n=91) patients (49 females and 42 males) (mean age of 14.1±5.8 years) were included. The frequency of DDE was 38.5% (35 patients). Genotype distributions were in Hardy-Weinberg equilibrium. No significant statistical association was found between DDE and the SNPs evaluated. A borderline association (p=0.09) was observed between DDE and the CC haplotype for SNP rs7975232 in VDR. In conclusion, the selected SNPs in VDR and PTH genes were not associated with DDE in the studied samples.
COMPARISON OF DYNESYS AND HYBRID SYSTEM FOR MULTI-SEGMENTAL LDD
Authors: Zhang Xin , Xiao Xiao , Wang Hongyu , Wang Song , Yang Dazhi , Peng Songlin
Published: June 2024

ABSTRACT Objective: To compare effectiveness of Dynesys and hybrid system in treating patients with multi-segmental lumbar degenerative disease (LDD). Methods: Patients involved in this retrospective study were divided into Dynesys (n = 22) and Hybrid (n = 13) groups. Clinical outcomes were evaluated using Oswestry Disability Index (ODI), and Visual Analogue Scale (VAS). Radiologic evaluations included X-ray, MRI, and CT. Furthermore, different complications were analyzed. Results: At the last follow-up, ODI and VAS of each group were improved (p < 0.05), and the range of motion (ROM) of operating segments decreased. However, Dynesys group preserved a larger extent of ROM at the final follow-up (p < 0.05). ROM of the upper adjacent segment was increased in both groups (p < 0.05), while the disc heights were decreased at the final follow-up (p < 0.05). Besides, Dynesys group had a more obvious decrease in the disc height of dynamic segments (p < 0.05). No significant difference existed in complications between both groups (p > 0. 05). Conclusion: In our study, similar satisfactory results were obtained in both groups. Both surgical procedures can be employed as effective treatments for middle-aged and physically active patients with multi-segmental LDD. Level of Evidence III; Retrospective Comparative Study.
SHORTENING OF CLAVICLE FRACTURES: PHYSICAL VERSUS IMAGE EXAMINATIONS
Authors: Beraldo Rodrigo Alves , Silva Caroline Izidorio Bernardes , de Paiva Junior Hélio Henrique , Alexandre Galdeano Ewerton , de Moraes Renato
Published: June 2024

ABSTRACT Objective: Determine the reliability of three different methods of evaluating bone shortening in displaced midshaft clavicle fractures (DCMF). Method: A cross-sectional analytical study evaluated bone shortening by metric tape (MT), radiography (X-ray), and computed tomography (CT). Twenty-six men had been evaluated and used clavícula not broken as control. The collection of data was of the blind type for three specialists. Differences and reliability were analyzed with the Friedman and Kappa tests and validated with the T-test (CI: 95%; significance index p<0.05; Software "R" version 3.2.2). Results: The MT measurements (control) showed abnormal distribution and significant statistical difference concerning the imaging tests (p=0.000008). There was a similarity between X-ray and CT and Kappa agreement of 0.65. The fractured clavicles presented similar measurements between the three methods (p=0.059), and the T-tests proved that the similarity was caused by chance or possible measurement errors. Conclusion: Measurement by metric tape showed a tendency to overestimate bone shortening. The CT showed more reliable results for the diagnosis; however, the X-ray was sufficient for decision-making by surgeons, and therefore, it is not possible to rule out the importance of this resource for DCMF. Level of Evidence IV; Case-Control Study.
RADIOGRAPHIC EVALUATION OF CONSERVATIVE TREATMENT OF DISTAL RADIUS FRACTURES
Authors: Cangussu Brenno Lopes , Baldanza Henrique Cruz , Carmo Ricardo Leão , Nobre Daniel Magalhães , Estanislau Alexandre Ramos , Barros Tomás Santos Vasconcelos
Published: June 2024

ABSTRACT Objective: This article aims to evaluate the evolution of radio-graphic parameters (radial tilt, volar tilt, and radial height) of distal radius fractures in patients indicated for conservative treatment at three different times: date of diagnosis, first outpatient visit within 2 weeks after closed reduction, and last outpatient visit. Methods: We included 84 patients seen at the emergency department of Hospital Municipal Odilon Behrens, with a diagnosis of distal radius fracture and an indication for conservative treatment. We considered only those patients who had serial radiographs taken at least three different times (n=69) in this analysis. Results: There was an improvement in radiographic parameters of volar tilt after closed reduction and immobilization, which was maintained until the last outpatient visit. Radial inclination and radial height showed increased values from the first to the second radiographic evaluation and both values had regression when comparing the second to the third (last) evaluation. Conclusion: Universal classification stable fractures tend to evolve well with conservative therapy. Level of Evidence II; Development of Diagnostic Criteria in Consecutive Patients (with Gold Standard of Reference Applied).
Effect of light and cytokinin on growth and curculin gene expression of Curculigo latifolia on in vitro culture
Authors: Muslihatin W. , Wibowo A. T. , Manuhara Y. S. W.
Published: June 2024

Abstract Despite being valuable for producing a natural sweetener Curculin, Curculigo latifolia has a low growth and difficult to domestificate. So, to solve this problem, propagation on in vitro culture will be an alternative method to propagated this spesies under different cytokinins and light condition. Cytokinins and light has major role in organogenesis, growth and gene expression of many species. Thus, in this study, we aimed to improve the Curculigo latifolia growth on in vitro condition and expression of curculin gene by combining cytokinins addition and different light exposure. Four weeks seedlings were sub-cultured into medium (MS free hormone) containing 3 mg/L benzyladenine (BA) and various concentrations of meta-Topolin (mT) including 0.1 mg/L, 0.5 mg/L, and 5 mg/L. The cultures then incubated under different light types (red, blue, white LED lights and white fluorescence light) with 16-h light/ 18-h dark photoperiod for 14 weeks at 25 ± 2°C. Several parameters, including plant height, leaf number, chlorophyll contents, stomatal structure, and density and curculin expression, were observed every week. Unexpectedly, our results showed that C. latifolia growth displayed significant improvement when it was treated under white LED light without any additional cytokinins. In sum, white LED light further improves plantlets phenotype, such as plant height, leaf number, chlorophyll production, and stomatal number and structure, whereas, red LED light lead to a decreased phenotypes but increase the curculin gene expression.
Ultrasonographic evaluation of thyroid glands and comparative hormonal analysis of domestic cats and neotropical wild felids
Authors: Antunes L.T. , Pereira Júnior O.C.M.
Published: June 2024

ABSTRACT This study aimed to determine the morphological and metric of the thyroid gland, and Total T4 and Free T4 hormonal values among domestic and wild felids without thyroid diseases. Thirty-three felids without thyroid diseases were evaluated, being 13 felids, one Panthera onca, three Pumas concolor, three small wild cats, three Pumas yagouaroundi, two Leopardus pardalis and one Leopardus wiedii, and 20 domestic felines. The animals were submitted to ultrasonography of the thyroid gland and to hormonal serum dosage of Total T4 and Free T4 by the technique of chemiluminescence. Subsequently, they were divided into groups according to weight, sex, and age. The mean volume of thyroid lobe was 0.11cm³ for domestic cats, 0.18cm³ for the mixed wild feline group (Leopardus pardalis, Leopardus tigrinus, Leopardus wiedii and Pumas yagouaroundi) and 1.57cm³ for the jaguar group (Panthera onca e Pumas concolor). The mean Total T4 and Free T4 were 2.55µg/dL and 1.23ng/dL for domestic cats, 1.46µg/dL and 1.89ng/dL for the mixed feline group and 0.68µg/dL and 0.82ng/dL for the jaguar group, respectively. Animals over 10 years old presented higher Free T4 values.
Effects of oleoresin capsicum on horses used in public security
Authors: Cruz M.S. , Dornbusch P.T.
Published: June 2024

ABSTRACT The effects of the Oleoresin Capsicum (OC) spray used by police forces to control civil disturbances are widely known and extensively described in numerous scientific articles regarding humans. However, with the advent of animal welfare concepts, the question arises as to whether horses exposed to OC in such events would experience the same effects described in humans. The objective of this study was to determine if Mounted Police horses exposed to OC exhibit the same symptoms described in humans. In this study, 18 healthy horses from the Military Police of Paraná, without a history of respiratory disease, were led through a cloud of gas created using six pepper spray dispensers. Physiological parameters including respiratory rate, heart rate, rectal temperature, and conjunctival color were evaluated 24 hours before exposure, 30 minutes, and 24 hours after exposure. Blood samples were collected for a complete blood count and blood gas analysis, and samples of the ocular mucosa were obtained using sterile swabs. Analysis of these parameters did not reveal effects analogous to those described in humans. The absence of ocular changes is directly correlated with the primary decontamination method in humans, which involves running with open eyes to allow the air to act against them. In the case of horses, the movement of their eyes while walking at an average speed of 6km/h in a walk and 18km/h in a trot generates airflow throughout the entire body of the animal. Additionally, pieces of tack and parts of the rider’s body form a barrier against the action of the OC agent by reducing the contact area. After 30 minutes and 24 hours post-exposure, no aggressive effects like those found in humans in the airways and ocular mucosa were observed.
Stem cell therapy as adjunctive in the management of anemia and thrombocytopenia partially responsive to corticosteroid in a dog treated with Phenobarbital - case report
Authors: Santos L.G. , Hasan J.A. , Teixeira B.A. , Viana A.R. , Krause A.
Published: June 2024

ABSTRACT This report describes a dog with anemia and ITP, associated with phenobarbital, treated with prednisolone with a good response after association with three intravenous transplantations of 2.5x106 allogenic Mesenchymal Stem-Cells. After the first transplantation, the number of platelets had an improvement, but started to decrease after three weeks. However, the dose of corticosteroid could be reduced. After the second and third administrations, new increases were observed. The platelet count varied from 102,000 to 365,000 until the end of follow-up and without increase of prednisolone doses. Although phenobarbital therapy has been associated with thrombocytopenia, it was not possible to change the anti-convulsant therapy. The response to corticosteroid-based therapy was partial. Cell therapy was followed by an improvement in platelet count with no observed side effects and therefore could be considered safe. Effects on platelet count were transitory, but until the end of follow-up, no severe thrombocytopenia was observed. Based on the observation that platelet numbers dropped a few weeks after cell therapy, more applications would be beneficial in order to maintain higher platelet counts.
Prediction of body weight of Brown Alpine goats by measuring body volume
Authors: Oliveira N.M. , Gurgel A.L.C. , Fonseca I. , Lopes J.F. , Difante G.S. , Ítavo L.C.V. , Araújo M.J. , Dias-Silva T.P. , Carvalho A.A. , Chay-Canul A.J.
Published: June 2024

ABSTRACT The objective was to estimate the body weight (BW) of Brown Alpine goats by means of body volume (BV) measurements. We used 132 pieces of information with measurements of BW, body length (BL) and thoracic perimeter (TP) from 22 goats evaluated fortnightly, between March and May 2023. Based on this information, the BV of the animals was calculated. Three mathematical models were evaluated - a linear model, a quadratic model, and an exponential model - with the measurement of BV. The goodness of fit of the equations was evaluated using the coefficient of determination (R2), mean square error (MSE) and root of the MSE (RMSE). The predictive ability of the models was evaluated by k-fold cross-validation (k = 10). A high positive correlation between BW and TP (r = 0.95) and BL (r = 0.94) was observed. The correlation between BW and BV was higher than the other correlations (r = 0.98). The linear model showed the lowest values of MSE (9.49) and RMSE (3.08). In the cross-validation, the linear and quadratic models presented estimates of the mean BW and the standard deviation of this weight similar to the real data, and high R2 values (0.95) of the data predicted by the observed ones. The analysis of the coefficient of correlation and concordance (CCC) also showed that these models have accuracy and precision (CCC > 0.95). Thus, the linear and quadratic models estimate the body weight of Brown Alpine goats with precision and accuracy.
Identification tools of Diplostomum spathaceum Rudolphi, 1819 (Diplostomida: Diplostomidae), a trematode parasite of herring gull (Larus argentatus)
Authors: Alshehri E. , Abdel-Gaber R. , Al-Quraishy S.
Published: June 2024

ABSTRACT Specimens of the genus Diplostomum von Nordmann, 1832 (Trematoda, Diplostomidae) were collected from the intestine of the herring gull, Larus argentatus (Laridae), from El-Manzala Lake (Port Said City, Egypt). This parasite species was morphometrically, morphologically, and molecularly studied using the internal transcribed spacer (ITS1-5.8S-ITS2) gene region. The presence of a trematode species of Diplostomum spathaceum Rudolphi, 1819 (Diplostomidae) was observed in 70 % of the examined gull species. This species has generic features of the genus Diplostomum. Distinct criteria that discriminated this species from congeners were the division for body parts, the egg-shaped forebody with a smaller length than the hind body, the ventral sucker being smaller in size than the oral one, the position of the ventral sucker being near to the holdfast, vitellaria was compact and rarely extend anteriorly to the holdfast organ, and smaller egg size. Partial ITS1-5.8S-ITS2 sequences from diplosomite recovered in this study showed that they grouped with members of the genus Diplostomum and formed a monophyletic group supporting the morphological description. Findings obtained from molecular analysis are consistent with data from morphological classification where the parasite recorded was morphologically similar to Diplostomum spathaceum with a first record in Egyptian gulls.
Determinação Experimental da Velocidade do Som pelo Efeito Doppler de uma Fonte Sonora em Rotação
Authors: Oliveria Júnior Abner Maia de , Bampi Igor Mendes de Aguiar Lysakovski , Amaral Jean Carlo Simpliciano do , Stein Victor Henrique , Zuleta Victor Hugo Mendes Zenteno , Ridenti Marco Antonio
Published: June 2024

Neste trabalho, propomos um método experimental para medir a velocidade do som por meio do efeito Doppler gerado por fonte sonora em rotação. Esse método experimental é comparado com o método mais convencional, comumente designado experimento do tubo ressonante, baseado na medição das frequências de ressonância acústica em um tubo com uma das extremidades fechadas. Embora o uso didático de uma fonte sonora girante para a demonstração do efeito Doppler não seja novidade, não encontramos na literatura um procedimento detalhado de aquisição experimental e tratamento quantitativo de dados que leve em conta a descrição completa da variação da frequência em função do tempo observada no referencial do laboratório. Este procedimento experimental foi formulado por alunos e professores do Instituto Tecnológico de Aeronáutica e aplicado no laboratório de física do curso FIS-26 (Mecânica II). Consideramos que o procedimento experimental aqui apresentado em detalhe é de interesse a um público mais amplo envolvido com ensino de física em nível universitário e médio.
O experimento de Eratóstenes ao luar
Authors: Gomes Tuan M. , Araújo Iago S.S. , Marques Ivo A.
Published: June 2024

No presente trabalho realizamos o experimento de Eratóstenes utilizando a Lua cheia como fonte de luz, ou seja, fizemos o experimento à noite. As medidas foram conduzidas nas cidades de Goiânia-GO e Carolina-MA. Os dados coletados foram interpretados utilizando-se três modelos diferentes: i) o modelo de mesma longitude (o modelo padrão de Eratóstenes); ii) o modelo generalizado para cidades separadas tanto em latitude quanto em longitude; iii) o modelo generalizado acrescido do valor da latitude da cidade mais ao Norte (a cidade de Carolina). Os valores obtidos nos três modelos, R 1 = ( 6,3 ± 0,1 ) × 10 3 k m, R 2 = ( 6,2 ± 0,2 ) × 10 3 k m e R 3 = ( 6,2 ± 0,2 ) × 10 3 k m, estão em pleno acordo com o valor do raio médio volumétrico da Terra, R N A S A = 6,371 × 10 3 k m. Essa comparação mostra a coerência dos modelos bem como a boa qualidade dos dados experimentais. Esperamos que o presente trabalho estimule debates sobre modelos teóricos e implementações experimentais voltados às estimativas de tamanhos e distâncias na Terra e no Sistema Solar.
Diagnostic accuracy of interleukin-6, interleukin-10 and tumor necrosis factor alpha cytokine levels in patients with mild cognitive impairment: systematic review and meta-analysis
Authors: Aquino Alana Mara Inácio de , Gomes Kedma Anne Lima , Brito Letícia Lorena Melo de , Lima Luciana Domingos de , Gomes Eneas Ricardo de Morais , Andrade Suellen Mary Marinho dos Santos
Published: June 2024

ABSTRACT There is growing evidence suggesting an association between neurodegeneration and inflammation playing a role in the pathogenesis of age-associated diseases, including Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI). Objective: A systematic review and meta-analysis were performed to verify evidence on the diagnostic accuracy parameters of the inflammatory cytokines interleukin-6 (IL-6), interleukin-10 (IL-10) and tumor necrosis factor alpha (TNF-α). Methods: A search of Medical Literature Analysis and Retrieval System Online (Medline), Scientific Electronic Library Online (SciELO), Web of Science and Science Direct databases was performed and nine observational studies associated with peripheral inflammatory biomarkers in MCI were identified. Mean (±standard deviation — SD) concentrations of these biomarkers and values of true positives, true negatives, false positives and false negatives for MCI and healthy controls (HC) were extracted from these studies. Results: Significantly higher levels of IL-10 were observed in subjects in the MCI group and Mini-Mental State Examination (MMSE) scores were lower compared to HC. For the other investigations, no differences were found between the groups. Our meta-analysis for the TNF-α biomarker revealed high heterogeneity between studies in terms of sensitivity and specificity. Conclusion: These findings do not support the involvement of inflammatory biomarkers for detection of MCI, although significant heterogeneity was observed. More studies are needed to evaluate the role of these cytokines in MCI, as well as in other stages of cognitive decline and all-cause dementias.
Phenotypic and Positron Emission Tomography with [18F]fluordeoxyglucose (FDG PET) differences in corticobasal syndrome: comparison of two cases
Authors: Beltrão Thais Winkeler , Maranhão Eduardo Barbosa de Albuquerque , Correia Victor Adill Gomes , Albuquerque Pedro Mota de , Pinheiro Mariana Gonçalves Maciel , Santos Rayanne Acioli Lins , Nunes Luiz Eduardo Duarte Borges , Brandão Simone Cristina Soares , Barbosa Breno José Alencar Pires
Published: June 2024

ABSTRACT Corticobasal syndrome (CBS) is a rare cause of dementia and comprises varied combinations of subcortical signs (akinetic-rigid parkinsonism, dystonia, or myoclonus) with cortical signs (apraxia, alien hand or cortical sensory deficit), usually asymmetric. We aimed to report and compare the clinical and neuroimaging presentation of two patients diagnosed with CBS. While case 1 had severe non-fluent aphasia associated with mild apraxia and limb rigidity, case 2 had a more posterior cognitive impairment, with a different language pattern associated with marked visuospatial errors and hemineglect. FDG PET played a significant role in diagnosis, suggesting, in the first case, corticobasal degeneration and, in the second, Alzheimer's disease pattern. CBS has been widely studied with the advent of new in vivo methods such as brain FDG PET. Studies that deepen the phenotypic and biomarker heterogeneity of CBS will be of great importance for better classification, prognosis, and treatment of the condition.
A falência e Ronaldo Duarte: agenciamentos a partir do cinema de um diretor perseguido
Authors: Machado Patrícia , Foster Lila
Published: June 2024

Resumo O artigo parte do curta-metragem A falência, de Ronaldo Duarte, ganhador da edição de 1967 do Festival Brasileiro de Cinema Amador do Jornal do Brasil, e da noção de agenciamento, buscando compreender os processos de produção e circulação do filme. Seguindo os caminhos das imagens, investigamos os motivos da censura do curta-metragem e a trajetória do cineasta, preso e torturado durante a ditadura militar. O percurso metodológico alia análise fílmica e o uso de fontes documentais diversas, mostrando os desafios enfrentados por jovens cineastas começando a sua trajetória profissional em meio ao período de censura e perseguição pelos agentes do Estado no país.
Inteligência emocional de trabalhadores de saúde e clima de segurança em hospitais na pandemia COVID-19
Authors: Silva Laudicéa Cardoso da , Rodrigues Ana Barbosa , Silva Francisco José da , Oliveira Paloma Moreira de , Oliveira Sherida Karanini Paz de , Carvalho Rhanna Emanuela Fontenele Lima de , Coelho Manuela de Mendonça Figueirêdo , Oliveira Roberta Meneses
Published: June 2024

RESUMO Objetivo: Analisar a relação entre inteligência emocional de trabalhadores de saúde em ambiente hospitalar e a percepção do clima de segurança na pandemia COVID-19. Método: Estudo transversal, analítico, realizado com 81 trabalhadores de saúde que atuaram em hospitais na pandemia, entre setembro-novembro de 2021. A coleta de dados foi realizada com formulário eletrônico reunindo questionário sociodemográfico/ocupacional e versões brasileiras do Safety Attitudes Questionnaire e Schutte Self Test. Aplicou-se teste de correlação de Spearman e análise de regressão linear simples/múltipla. Resultados: O aumento de 1 ponto nos níveis de inteligência emocional repercutiu no aumento de 0,487 pontos nos níveis de percepção do clima de segurança. O preditor mais significativo dessa percepção foi a habilidade de manejo das emoções de outros (β=0,334; p=0,003; R2=0,168). Conclusão: Um maior nível de inteligência emocional de trabalhadores de saúde em ambiente hospitalar tem relação com uma maior percepção do clima de segurança na pandemia COVID-19.
Sexual and reproductive health: analysis of the content published in two Brazilian scientific nursing events
Authors: Queiroz Ana Beatriz Azevedo , Carvalho Ana Luiza de Oliveira , Bezerra Juliana da Fonsêca , Gaspar Isabelle Mangueira de Paula , Titara Natália Moreira Leitão , Cardoso Fernanda Martins , Rosa Júlia Verli , Santos Laira Maria da Silva
Published: June 2024

ABSTRACT Objective: To analyze the content published in the Proceedings of the 71st Brazilian Nursing Congress and the 20th National Research Seminar in the field of sexual and reproductive health. Method: Qualitative, descriptive study, whose data sources were the annalsof two 2019 events that were related to Sexual and Reproductive Health. Content analysis and lexical typology were carried out with the aid of the IRAMUTEq® software. Results: In a universe of 3,433 abstracts, 603 were analyzed and showed a higher prevalence of qualitative studies and experience reports, focusing on the maternal-child area and on the pathologizing and medicalizing processes of women's health, with incipient use of software in the analysis. However, there were signs of health promotion and humanized care. Conclusion: The dissemination of studies in the field of sexual and Reproductive Health seems to be in a conflict between accommodation and resistance, at the same time that it maintains old imperatives of the hegemonic domain, seeking to overcome them with new methodologies and care based on integrality and equity.
Saúde sexual e reprodutiva: análise de conteúdo publicado em dois eventos científicos brasileiros de enfermagem
Authors: Queiroz Ana Beatriz Azevedo , Carvalho Ana Luiza de Oliveira , Bezerra Juliana da Fonsêca , Gaspar Isabelle Mangueira de Paula , Titara Natália Moreira Leitão , Cardoso Fernanda Martins , Rosa Júlia Verli , Santos Laira Maria da Silva
Published: June 2024

RESUMO Objetivo: Analisar o conteúdo publicado nos Anais do 71º Congresso Brasileiro de Enfermagem e do 20º Seminário Nacional de Pesquisa em Enfermagem na área da saúde sexual e reprodutiva. Método: Estudo qualitativo, descritivo, cujas fontes de dados foram resumos com temáticas referentes à Saúde Sexual e Reprodutiva nos Anais de 2019 dos eventos. Realizou-se análise de conteúdo, tipo lexical com auxílio do software IRAMUTEq®. Resultados: Dos 3.433 resumos recrutados foram analisados 603, sendo grande parte de estudos qualitativos e relato de experiências, com enfoque na área materno-infantil e nos processos patologizantes e medicalizadores da saúde da mulher. Entretanto, houve sinalizações de promoção de saúde e cuidados humanizados. Conclusão: A divulgação dos estudos da Área da Saúde Sexual e Reprodutiva parece estar num conflito entre acomodação e resistência, pois, ao mesmo tempo que mantém antigos imperativos do domínio hegemônico, busca superá-los com novas metodologias e cuidados pautados na integralidade e equidade.
Complexo da Esclerose Tuberosa e rins: o que os nefrologistas devem saber
Authors: Monich Aline Grosskopf , Bissler John J. , Barreto Fellype Carvalho
Published: June 2024

Resumo O complexo da esclerose tuberosa (CET) é uma doença autossômica dominante caracterizada pelo desenvolvimento de hamartomas no sistema nervoso central, coração, pele, pulmões e rins e outras manifestações, incluindo convulsões, tubérculos corticais, linhas de migração radial, autismo e deficiência cognitiva. A doença está associada a variantes patogênicas nos genes TSC1 ou TSC2, resultando na hiperativação da via mTOR, um importante regulador do crescimento e metabolismo celular. Consequentemente, a hiperativação da via mTOR leva à proliferação anormal do tecido e ao desenvolvimento de tumores sólidos. O envolvimento renal no CET é caracterizado pelo desenvolvimento de lesões císticas, carcinoma de células renais e angiomiolipomas renais, que podem progredir e causar dor, sangramento e perda da função renal. Nos últimos anos, houve uma mudança notável na abordagem terapêutica do CET, especialmente no tratamento das manifestações renais. Os inibidores de mTOR surgiram como a principal opção terapêutica, enquanto intervenções cirúrgicas como nefrectomia e embolização são reservadas principalmente para complicações que não respondem ao tratamento clínico, como hemorragia renal grave. Esta revisão se concentra nas principais características clínicas do CET, nos mecanismos subjacentes ao envolvimento renal, nos recentes avanços na terapia para lesões renais e nas perspectivas futuras.
Viability of simultaneously selecting for grain yield and seed physiological quality in maize
Authors: Costa Júlia Carvalho , Vilela Guilherme Leite Dias , Bruzi Adriano Teodoro , Piza Mateus Ribeiro , Pádua José Maria Villela , Santos Heloisa Oliveira dos
Published: June 2024

ABSTRACT: Currently, the demand is not only for more productive corn hybrids, but also for those with high physiological seed quality. Seed quality is considered the sum of genetic, physical, physiological and sanitary attributes that directly interfere in plant vigor. The objective of this study was to evaluate the physiological parameters of the seeds of parents and maize inter varietal hybrids obtained in a reciprocal recurrent selection program through physiological and image analysis techniques and either to study the feasibility of simultaneously selecting for seed physiological quality and grain yield. Two experiments were performed, one in the field and the other in the laboratory. The evaluated traits in the field were days of female flowering, days of male flowering, insertion of the 1st ear, plant height and grain yield. For the physiological quality, the attributes of germination at four days, germination at seven days, vigor by the cold test, emergence speed index, and the ratio of the root length to shoot length were obtained using GroundEye®. Heterosis was measured for the agronomic and physiological traits. Through the contrast between the inter varietal crosse hybrids and reciprocals we measured the maternal effect. The magnitudes of heterosis allowed us to infer that as greater as the number of selection and recombination cycles, on average, greater heterosis for the traits grain yield and seed germination. The correlated response indicated that, high yield intervarietal hybrids have better seed physiological quality.
Use of the X-ray technique to evaluate the internal morphology of seeds of green manure species
Authors: Zacharias Marina Barros , Cicero Silvio Moure , Gomes-Junior Francisco Guilhien , Forti Victor Augusto , Silva Josué Bispo da
Published: June 2024

ABSTRACT: Image analysis through X-ray technique has been receiving great attention due to its importance in identifying internal damage in seeds quickly and accurately, in addition to being a non-destructive method. The aim of this study was to assess the use of X-rays to evaluate the internal morphology of seeds of green manure species. Seeds of Lupinus albus L., Cajanus cajan (L.) Millsp., Canavalia ensiformis (L.) DC. and Stylosanthes spp. were radiographed. Two hundred seeds were studied for each species, and intact seeds, seeds with mechanical damage, damage caused by insects and deteriorated tissues were recorded, considering the severity and location of the damage. The same seeds were subjected to a germination test. It was concluded that image analysis using X-ray technique was effective in detecting internal damage in seeds of some green manure species and it has relationship with negative aspects in germination.
Cuidados Paliativos em hospital oncológico de referência: atenção primária, diagnóstico tardio e mistanásia
Authors: Cunha Thiago Rocha da , Sampaio Madalena de Faria , Corradi-Perini Carla , Siqueira José Eduardo de , Guirro Ursula Bueno do Prado
Published: June 2024

RESUMO Estudo retrospectivo, observacional, transversal que analisou os encaminhamentos de 120 pacientes oncológicos para uma equipe de Cuidados Paliativos (CP) em hospital público de referência em oncologia no norte do Paraná, em fevereiro de 2020. Os dados foram coletados nos prontuários e analisados com base no suporte teórico da bioética. Observou-se que expressiva maioria dos pacientes 82,5% chegou ao hospital com doença avançada e 59,7% foram encaminhados para CP em menos de seis meses após a entrada no serviço. Parte importante dos pacientes chegou sem possibilidade de terapia específica oncológica, sendo, por isso, rapidamente encaminhados aos CP. Esses e outros achados da pesquisa sustentam uma discussão entre cuidados paliativos, atenção primária à saúde e diagnóstico oncológico tardio. O artigo conclui que, no contexto dos CP, as mortes relacionadas ao diagnóstico oncológico tardio, antecedidas de sofrimentos evitáveis e decorrentes de falhas estruturais em políticas públicas de saúde, expressam uma problemática forma de mistanásia.
Facilitators and barriers in the organization of physiotherapists’ work in a specialized rehabilitation center
Authors: Silva Natasha Felipe da , Paiva Júnior José Erivonaldo Ferreira , Brito Geraldo Eduardo Guedes de , Guedes Dimitri Taurino , Vieira Gabriel Nóbrega , Neves Robson da Fonseca
Published: June 2024

Abstract Introduction: Physiotherapy is part of the multidiscipli-nary team of specialized rehabilitation centers and seeks to offer users comprehensive care from a biopsychoso-cial perspective. Objective: To get to know facilitators and obstacles related to the physiotherapists’ work orga-nization in a specialized rehabilitation center present in their care practices provided and recommended for persons with disabilities. Methods: We conducted a qualitative, descriptive study, taking the case study as a guiding model, developed and analyzed from methodological resources of ethnography. Three data collection strategies were used: documentary research, direct observation and interviews with physiotherapists. Data were analyzed through the reconstruction of scenes, articulating the elements captured in the data production process. Results: The findings regarding the reception and welcoming pointed out how the aspects of demand and overloaded agenda make it difficult to adopt the embracement, however, welcoming practices are perceived during the assistance provided by the physiotherapist. Assessments and reassessments need to be reformulated, taking a common language base as a reference and for that it is necessary to induce manage-ment with an impact on the organization of work. The singular therapeutic project is not yet a reality in the institution, as its adoption also leads to changes and the dismantling of the established culture of assistance through productivity pressured by demand. Conclusion: Our study made it possible to identify the contribution of knowledge about the organization of work in the specialized center for the implementation or not of an approach that is closer to what is desired in terms of care in the biopsychosocial perspective.
Facilitadores e barreiras na organização do trabalho de fisioterapeutas em um centro especializado em reabilitação
Authors: Silva Natasha Felipe da , Paiva Júnior José Erivonaldo Ferreira , Brito Geraldo Eduardo Guedes de , Guedes Dimitri Taurino , Vieira Gabriel Nóbrega , Neves Robson da Fonseca
Published: June 2024

Resumo Introdução: A fisioterapia integra a equipe multidisciplinar de centros especializados em reabilitação e busca ofertar um cuidado integral na perpectiva biopsicosso-cial aos usuários. Objetivo: Conhecer facilitadores e obstáculos relacionados à organização do trabalho do fisioterapeuta em um centro especializado em reabilita-ção, presente em suas práticas de cuidado prestadas e preconizadas à pessoa com deficiência. Métodos: Trata-se de um estudo qualitativo, descritivo, tomando como modelo condutor o estudo de caso, desenvolvido e analisado a partir de recursos metodológicos da etnografia. Utilizaram-se três estratégias de coleta de dados: pesquisa documental, observação direta e entre-vistas com os fisioterapeutas. Os dados foram analisa-dos por meio da reconstrução de cenas, articulando os elementos capturados no processo de produção dos dados. Resultados: Os aspectos de demanda e agenda sobrecarregada dificultam a adoção do acolhimento, contudo percebem-se práticas acolhedoras durante a assistência prestada pelo fisioterapeuta. As avaliações e reavaliações precisam ser reformuladas, tomando como referencial uma base de linguagem comum e, para isso, é preciso uma indução da gestão com impacto sobre a organização do trabalho. O projeto terapêutico singular ainda não é realidade na instituição, visto que a adoção do mesmo também remete a mudanças e ao desmonte da cultura estabelecida de assistência por produtivi-dade pressionada pela demanda. Conclusão: O estudo permitiu identificar a contribuição do conhecimento sobre a organização do trabalho no centro especializado para a efetivação ou não de uma abordagem que se aproxime do que se almeja em termos de cuidado na perspectiva biopsicossocial.
Agentes populares no contexto da pandemia de Covid-19: educação popular em saúde na construção de territórios saudáveis e sustentáveis
Authors: Silva Carolina Veras Pessoa Da , Albuquerque Paulette Cavalcanti de , Mello Lívia Milena Barbosa de Deus e , Tavares Mariane Silva
Published: June 2024

Este estudo analisou as experiências desenvolvidas pelos Agentes Populares de Saúde (AgPS) na Campanha Mãos Solidárias, entre os anos 2020 e 2022, suas aproximações com a Política Nacional de Educação Popular em Saúde e com o conceito de Territórios Saudáveis e Sustentáveis. Trata-se de uma pesquisa documental, qualitativa e analítica, cujas fontes de dados foram coletadas nas mídias sociais da campanha, jornais e produções acadêmicas do tema. Os AgPS fomentaram o protagonismo popular nos territórios por meio de estratégias de mobilização pelo direito a saúde, educação em saúde, comunicação popular e cuidado em saúde. Identificaram e fortaleceram os saberes populares do território pela articulação intersetorial entre Saúde, Alimentação, Trabalho e Renda, Direitos, Comunicação e Educação. Este trabalho identificou a dificuldade de articulação das ações com o Sistema Único de Saúde (SUS) e também a necessidade de fortalecimento de políticas públicas relacionadas ao tema.
Indígenas universitários no primeiro semestre da pandemia de Covid-19: experiências em uma moradia estudantil
Authors: Souza Raniel Martinha de , Luna Willian Fernandes , Teixeira Iraí Maria de Campos
Published: June 2024

O artigo descreve experiências de indígenas universitários que viveram em uma moradia estudantil durante o período de distanciamento social ampliado no primeiro semestre da pandemia de Covid-19. Trata-se de uma pesquisa qualitativa, com utilização de diário de campo, levantamento documental e entrevistas. Foi realizada análise temática de conteúdo, sob a óptica dos conceitos de situação-limite, inéditos viáveis e resiliência. Foram duas categorias identificadas: sofrimento no contexto do distanciamento social e estratégias de superação de dificuldades. Vivenciaram incertezas e limites trazidos pela pandemia, medos por estarem distantes e adoecimentos. Como enfrentamento, surgiram adaptações no ensino, na pesquisa e na extensão; estratégias individuais para além de atividades acadêmicas; e busca de construções coletivas possíveis visando à resiliência e à desconstrução de visões estereotipadas no ambiente acadêmico.
Vigilância Popular em Saúde no sul do Brasil: expressões de um território que pulsa
Authors: Meneses Michele Neves , Kuhn Marla Fernanda , Almeida José Carlos de , Carneiro Fernando Ferreira , Rocha Cristianne Maria Famer
Published: June 2024

Em todo o território nacional tem sido possível identificar variadas iniciativas de protagonismo popular na perspectiva da promoção e da proteção da vida, em busca de territórios saudáveis e sustentáveis. Este texto objetiva descrever a experiência de um processo histórico, dinâmico e permanente de luta e mobilização social contra a violação de direitos fundamentais por saúde e sustentabilidade ambiental, no Assentamento Santa Rita de Cássia II, em Nova Santa Rita, Rio Grande do Sul, Brasil. Essa experiência pode ser considerada como uma ação de fortalecimento e reinvenção da vigilância em saúde pela população, portanto uma Vigilância Popular em Saúde, transgredindo fronteiras fragmentadoras da hegemonia dos saberes, percorrendo caminhos que priorizam e enfrentam os problemas do seu território vivo, território que pulsa e luta desde sua retomada.
“I live in a very bourgeois world, I don’t live in the outskirts”: childhood non-vaccination and the intersection of race, class and gender
Authors: Matos Camila Carvalho de Souza Amorim , Tavares Jeane Saskya Campos , Couto Marcia Thereza
Published: June 2024

This article analyzes how race, gender, social class and spatiality markers intersect and are reflected in health decision-making, more specifically in childhood (non)vaccination. This qualitative study was conducted in two Brazilian cities: Florianópolis (SC) and São Luís (MA), and included families with children up to six years old. This article analyzes the narratives of 19 caregivers in Florianópolis who chose not to vaccinate (fully or partially) the child(ren) under their responsibility. In-depth interviews and thematic content analysis were conducted. Gender was an important marker in intra-family decision-making, while social class, race and spatiality emerged as important markers in the perception of who are the “us” who don’t need vaccines and the “others” who do. The findings are discussed using the theoretical framework of whiteness and neoliberal parenting studies.
Stigma against Mental Illness and Mental Health: the role of Social Media
Authors: Rizzo Amelia , Calandi Lorena , Faranda Monica , Rosano Maria Grazia , Carlotta Viviana , Vinci Enrica
Published: June 2024

In social psychology, prejudice is a negative attitude toward a person belonging to a specific social group or a condition that is assumed negatively influences interpersonal relationships. In social psychiatry, the term stigma refers to a set of negative factors associated with individuals with a mental disorder. Stigma related to mental health issues is prevalent in collective thinking, widespread, and difficult to modify. Common behaviours among people include fear of interacting with individuals with psychological issues due to their perceived unpredictability. Social media platforms play a powerful role in informing, raising awareness, and influencing public perceptions of mental disorders. On the one hand, they provide an unprecedented platform for sharing personal experiences, reducing stigma, and promoting mutual support among individuals facing similar challenges. On the other hand, there is a risk that these platforms can spread misleading information, harmful stereotypes, and sensationalistic or sanitized representations, negatively impacting both public perception and the well-being of affected individuals.
Preditores de Risco Cardiovascular na Atenção Primária à Saúde: Reflexões sobre a adoção de modelos não-laboratoriais
Authors: Damázio Laila Cristina Moreira , Andrade Beatriz Pimentel de Oliveira , Gomes José Victor Ribeiro Silva , Ruiz Kananda Oliveira Garcia , Amaral Mariela Svízzero , Fialho Milena Henriques , Drumond Rafael Fonseca , Ribeiro Vitor de Oliveira
Published: June 2024

Este artigo levanta considerações sobre o uso de ferramentas de estratificação do Risco Cardiovascular (RCV) na Atenção Primária à Saúde (APS), com foco no comportamento de modelos não-laboratoriais como alternativa às predições laboratoriais. Reflete-se sobre tal objeto a partir de pesquisa empírica de metodologia transversal e exploratória, voltada para o comportamento de duas escalas em uma população adulta (entre 40 e 74 anos), com comorbidades (Hipertensão e/ou Diabetes) e sem agravos cardiovasculares registrados, em uma cidade de médio porte de Minas Gerais. No trabalho, intitulado projeto “CardioRisco”, avaliou-se o grau de concordância entre a estratificação de RCV realizada pelo Escore de Risco Global de Framingham, a partir de informação sobre colesterol, e pela versão não-laboratorial da calculadora HEARTS, que utiliza o Índice de Massa Corporal em substituição ao dado sérico. Neste artigo, analisa-se o resultado geral da pesquisa, no qual, para a amostra constituída, constatou-se uma concordância mínima entre os estratificadores, bem como apresenta-se recomendações em relação ao manejo do RCV no contexto da APS, com destaque para a importância da avaliação integral do paciente de notório risco, como pessoas com Diabetes.
O processo de harmonização jurídica em integrações regionais: uma análise sob a perspectiva do sistema internormativo da União Europeia
Authors: Vieira Oliveira Francielle
Published: June 2024

Este artigo explora a relevância e a intricada natureza do processo de harmonização jurídica em integrações regionais, oferecendo uma perspectiva à luz do sistema internormativo, com ênfase no exemplo da União Europeia. Destacamos o papel dos juízes dos tribunais nacionais nesse processo de harmonização jurídica, particularmente na aplicação das normas harmonizadas, por meio do diálogo interjurisdicional facilitado pelo reenvio prejudicial.
Software Tool for Drone Flight Management in Supervising Building Extern Façades
Authors: Bacca Cortes Bladimir , Barrera Mateo , Castillo García Jaiver
Published: June 2024

In contemporary times, monitoring building façades is a task that require extensive inspections in wide areas of work, working at different heights and in diverse weather situations. To address this challenge, this work proposes the development of a software tool called DroneFaçade to manage the drone flight, generate an image mosaic of a building façade and providing the corresponding report of the inspection mission. This allows continuous monitoring and registering the state of the façade through time. DroneFaçade was developed in four modules namely configuration, execution, data processing and report generation modules. The operational pipeline of DronFaçade includes three phases: first, the configuration module of DroneFaçade is used to introduce the way points, fulfill other information about the mission, trajectory planning and sensors to be used; second, the execution module of DroneFaçade connects to the drone, then the flight mission starts and also the data acquisition; finally, the data processing and report modules of DroneFaçade can compute the mosaic using the image previously stored in a SQL database, and users can generate a PDF report of the mission. Quantitative tests were performed to measure the image mosaic accuracy of DroneFaçade. As a result, the mosaic image computed by DronFaçade has low structural errors, preserves phase congruency and the magnitude of the image gradients, keeps high correlation and an appearance similarity of up 92.6% with respect to the real scene.