bluuebunny/crossref_metadata_2025 huggingface dataset:
Chitosan production from agro-wastes by Aspergillus tubingensis: A sustainable approach for beef burger quality improvement
Authors: Amin Shimaa A. , Abou-Taleb Khadiga A. , Abd-Elhalim Basma T. , Abdelghani Dina Y. , Ahmed Rania F.
Published: June 2024

Background
Chitosan is commonly obtained by deacetylation of chitin from crustacean shell wastes such as shrimp and crab, but unfortunately, these sources appear limited for their unavailability. So, an alternative abundant chitin source is in need as fungi mycelia.
Results
In this study, chitosan production through submerged (SMF) and solid-state fermentation (SSF) of Aspergillus tubingensis utilizing various agro-wastes and by-products like whey, blackstrap molasses, beet waste, rice (husk& straw), wheat bran and sawdust as a sole carbon source was investigated. The best waste was beet waste (33.12% and 38.61% of chitin and chitosan yields for SSF and whey (whey (24.22% and 35.90% of chitin and chitosan yields) for SmF, as compared to the control of sucrose (17.11% and 20.38% of chitin and chitosan yields) after 8–12 and 8 days of incubation, respectively. The fungal polymer had antibacterial activity against Staphylococcus aureus DSMZ20231,Salmonella Typhimurium ATCC14028,Bacillus cereus DSMZ345, Pseudomonas fluorescens NRRL800, and Escherichia coli ATCC69373 at a significant concentration of 1.0% were assayed using Kirby-Bauer disc diffusion method. Staph. aureus DSMZ20231& S. Typhimurium ATCC14028 were more susceptible to chitosan, which gave the largest zone inhibition of 47 and 43 mm, respectively. Moreover, the polymer's antibacterial activity was tested in the broth medium during different incubation periods (12-48h). results indicated that all tested pathogenic strains exhibited complete inhibition after 24 h incubation except B. cereus DSMZ345 was the most stable up to 48h. Application of fungal chitosan (1.0%) for a laboratory-manufactured beef burger led to improve quality analysis of the texture, physical or technological and chemical properties than control without chitosan. At the same time, beef burger supplemented with chitosan was significantly accepted overall by the panelist than the control. Therefore, fungal chitosan extended the beef burger's shelf life and maintained its quality indices during freezing storage.
Conclusions
Fungal chitosan is a beneficial natural antimicrobial, and applying it to beef burgers improves microbiological, technological, and chemical quality while also extending shelf life by up to 8 weeks, making it a viable alternative to chemical protective additives. Future research on this fungal chitosan will focus on large-scale meat or poultry preservation or additive applications.
CELLeBT: exploring physical B cell-T cell clonal interactions through single-cell multi-omics
Authors: Bashford-Rogers Rachael , Shohan Mohammad Umer Sharif , Tucci Felicia , Antanaviciute Agne , Pernes Jane , Walker Catherine , Wu Shihong , Overend Lauren , Leedham Simon , Koohy Hashem
Published: June 2024

CELLeBT is a novel machine learning tool to decipher B cell-T cell interactions from single cell multi-omics data through leveraging droplets containing both a B cell receptor (BCR) and T cell receptor (TCR), thus containing both a B and a T cell. CELLeBT provides multiple types of information about B cell-T cell interactions, including the relative frequency of stable cellular interactions, the clonal nature and network of interactions, and the molecular drivers of these interactions as demonstrated through analysis of RCC and PDAC datasets, with unprecedented detail.
Bacterial isolates from Drinking water river sources exhibit multi-drug resistant trait
Authors: Popoola Bukola Margaret , Ogwerel Jemimah Pearl , Oladipo Oluwatosin Gbemisola
Published: June 2024

Freshwater habitat is a natural reservoir for antimicrobial resistance (AMR). AMR is known to pose serious human, animal, and environmental public health threats. This study aimed at evaluating the physicochemical and microbiological properties of five selected rivers (Apitipiti 1, Apitipiti 2, Apitipiti 3, Sogidi, and Aba Apa Akinmorin) in Oyo town, Nigeria, as well as the antibiotic resistance pattern of isolated bacterial species, using conventional methods. Most physicochemical parameters were within WHO and NIS permissible limits. Of the rivers, Sogidi had the highest microbial load (6.36 log CFU/mL) while Apititipiti 1 had the lowest (5.76 log CFU/mL). A total of thirty-three (32) bacterial species were isolated and identified as: Aeromonas (9), Bacillus (2), Corynebacterium (13), Lactobacillus (1), Pseudomonas (2), Staphylococcus (4), and Streptococcus (1). Pearson’s correlation matrix indicated that there were significant (p<0.05) interactions among pH, electrical conductivity, temperature, sulphate and chloride salts, BOD and COD. Of all these, 81.8 % were multidrug-resistant, with Corynebacterium kutscheri and Aeromonas spp. isolated from Apitipiti 2 and Aba Apa Akinmorin rivers respectively, exhibiting a relatively high antibiotic resistance of 90.9 %. This study reveals that these rivers maybe unfit for consumption as multidrug-resistant bacteria of public health risk were associated with them.
Chinese herbal formula Regan Saibisitan alleviates inflammation and improves chronic bronchitis via inhibiting the JAK2/STAT3 pathway
Authors: Ding Xiaorui , Zheng Ruifang , Kader Kaderyea , Han Yulin , Xu Lei , Zeng Xin , Xing Jianguo , Wang Shoubao
Published: June 2024

Background: Chronic bronchitis (CB) is characterized by persistent, non-specific inflammation in the trachea, bronchial mucosa, and surrounding tissues mainly resulting from infectious or non-infectious factors. Regan Saibisitan is a classic prescription used to treat cough, pneumonia, and other respiratory infections in Uygur medicine. However, its mechanism in treating chronic bronchitis has not been reported. This study aimed to explore the efficacy and mechanism of Regan Saibisitan in CB mice.
Methods: Regan Saibisitan extract (RGS) was prepared, and the components in RGS were analyzed by ultra-performance liquid chromatography-ion trap-electrostatic field orbital trap mass spectrometry (UPLC-LTQ-Orbitrap-MS/MS). The CB mouse model was established by cigarette smoking (CS) and intranasal administration of lipopolysaccharide (LPS, 20μg), histological changes of bronchial epithelium, collagen deposition, mucus secretion in lung tissue and inflammatory factors were assayed. Transcriptomics analysis was performed to detect the differentially regulated genes in lung tissue of CB mice treated with RGS. The effect of RGS on JAK 2/STAT 3 pathway was investigated in CB mice and NCI-H 282 cells treated with PMA using western blotting, ELISA,and immunohistochemical analysis. The JAK2 inhibitor AG490 was used in NCI-H292 cells to verify the effect of RGS on JAK2/STAT3 pathway.
Results: A total of 286 compounds were identified in RGS, in which Liquiritin, Formononetin, Isoliquiritigenin, Salidroside, Ferulic and Morphine were reported to have significant anti-inflammatory activities. RGS treatment significantly improved the thickening of bronchial epithelium, decreased collagen deposition and secretion of mucus, and the levels of inflammatory factors in CB mice. Transcriptomics analysis showed that most of 402 differentially expressed genes in RGS-treated CB mice were related to inflammatory response. The results in CB mice and NCI-H292 cells showed that RGS reduced the phosphorylation level of JAK 2 and STAT 3 . In addition, the use of JAK2 inhibitor AG490 confirmed that JAK2/STAT3 pathway played a key role in the effects of RGS on CB.
Conclusions: RGS suppresses inflammation and improves chronic bronchitis in NCI-H292 cells and CB mice, at least in part, via inhibiting the JAK2/STAT3 pathway. This study demonstrated that RGS could be a potential drug in treating CB disease.
Genomic perspective on the bacillus causing paratyphoid B fever
Authors: Weill François-Xavier , Frézal Lise , Tran-Dien Alicia , Zhukova Anna , Brown Derek , Chattaway Marie , Simon Sandra , izumiya Hidemasa , Fields Patricia , de Lappe Niall , Kaftyreva Lidia , Xu Xuebin , Isobe Junko , Clermont Dominique , Njamkepo Elisabeth , Akeda Yukihiro , Issenhuth-Jeanjean Sylvie , Makarova Mariia , Wang Yanan , Hunt Martin , Jenkins Brent , Ravel Magali , Guibert Véronique , Serre Estelle , Matveeva Zoya , Fabre Laetitia , Cormican Martin , Yue Min , Morita Masatomo , Iqbal Zamin , Nodari Carolina Silva , Gandara Maria Pardos de la , Hawkey Jane
Published: June 2024

Paratyphoid B fever (PTB) is caused by an invasive lineage (phylogroup 1, PG1) of Salmonella enterica serotype Paratyphi B (SPB). Here, we provide a genomic overview of the population structure, geographic distribution, and evolution of SPB PG1 by analysing genomes from 568 historical and contemporary isolates, obtained globally, between 1898 and 2021. We show that this pathogen existed in the 13th century, subsequently diversifying into 11 lineages and 38 genotypes with strong phylogeographic patterns. Following its discovery in 1896, it circulated across Europe until the 1970s, after which it was mostly reimported into Europe from South America, the Middle East, South Asia, and North Africa. Antimicrobial resistance recently emerged in various genotypes of SPB PG1, mostly through mutations of the quinolone-resistance-determining regions of gyrA and gyrB. This study provides an unprecedented insight into SPB PG1 and essential genomic tools for identifying and tracking this pathogen, thereby facilitating the global genomic surveillance of PTB.
Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignancies
Authors: Yu Shoukai , Qian Lingmei , Xu Liling , Ma Jun
Published: June 2024

Gene expression profiling plays a crucial role in understanding the role of Krüppel-like factor 4 (KLF4) in prognosis and the tumor immune microenvironment in various malignancies. The transcription factor KLF4 plays a crucial role in various cellular processes, including cell differentiation, proliferation, and apoptosis. Genetic alterations and aberrant KLF4 expression have been observed in many malignancies, thus suggesting a potential role as a prognostic marker and therapeutic target. Herein, a systematic analysis of KLF4 genetic alterations revealed the mutation, amplification, and deletion frequencies across different cancer types. The genetic alteration patterns varied across malignancies, thus highlighting the diverse roles of KLF4 in different tumor contexts. Secondly, the prognostic significance of KLF4 expression was assessed in multiple cancers. High expression levels of KLF4 were associated with better clinical outcomes in kidney renal clear cell carcinoma, while low KLF4 expression correlated with a favorable prognosis in certain malignancies. In conclusion, the genetic alterations, dysregulated RNA expression, and prognostic implications of KLF4 in malignancies underscore its significance in cancer biology. The findings present will aid in understanding the role of KLF4 in tumor biology and its association with immune responses. Further investigations should focus on further elucidating the functional roles and regulatory mechanisms of KLF4 to further assess its potential as a therapeutic target and predictive biomarker in cancer management.
Rare Non Tubal Ectopic Pregnancies in a Tertiary Care Hospital
Authors: Pudami Rajyalakshmi
Published: June 2024

Non-tubal ectopic pregnancies (NT-EPs) are infrequent yet potentially life-threatening conditions, with an incidence scaling from 5–8.3% of all ectopic pregnancies. In this observational descriptive study, seven cases of non-tubal ectopic pregnancies were identified among 36,396 deliveries that occurred between July 2019 and June 2023. Demographic information, symptoms, β-hCG levels, ultrasound detections, management approaches, and treatment results of patients were presented. This study includes two cases of rudimentary horn ectopic treated with resection of the rudimentary horn, a case of cervical pregnancy treated with suction evacuation after ligation of descending cervical arteries and placement of Foley's balloon tamponade after medical treatment, a case of ovarian pregnancy treated with oophorectomy, a case of cesarean scar pregnancy managed with excision of ectopic sac preserving the uterus, another case hysterectomy was needed, and a case of interstitial pregnancy treated with surgical resection of ectopic and suturing the site keeping surgical for strength after failed medical treatment with Methotrexate 2 doses. This manuscript summarizes the experience of a single centre in managing NT-EPs and the diversity of management in different types of non-tubal ectopic pregnancies, emphasizing the importance of a high index of suspicion to enable appropriate treatment, thereby reducing mortality and maternal morbidity and preserving future fertility.
An ecological mechanism determining the direction of species evolution
Authors: Wu Haoyuan , Wu Yonghua
Published: June 2024

Each species possesses a specific adaptive evolutionary direction, yet the mechanism determining this direction remains less clear. Here, we investigated this mechanism by conducting experimental evolution on Escherichia coli. We introduced an E. coli strain (lac-), initially unable to utilize lactose due to a frameshift mutation, into two different culture media: one medium (L) containing ample sodium acetate and lactose as carbon sources, and the other medium (G) containing abundant glucose and lactose as carbon sources. After 20 days of experimental evolution, our findings revealed that all L-populations underwent parallel evolution through reverse mutation to utilize lactose (lac+), resulting in relatively high fitness gain, while all G-populations did not transition towards lactose utilization but instead maintained the utilization of glucose, which provides higher fitness gain. When lac+ (lactose-eater) and lac- (acetate-eater) were co-cultured in L medium, all lac- individuals were eventually eliminated, while lac+ individuals were consistently selected and retained, indicating that adaptive mutations favoring the evolutionary direction with higher fitness gains competitively exclude those adapted to relatively lower fitness-gain directions. Our findings demonstrate that natural selection, operating between mutations in different adaptive directions, promotes the retention of high-fitness gain directions while eliminating lower-fitness gain directions. This selective pressure compels species to evolve exclusively towards directions offering the highest relative fitness gains, serving as a crucial ecological mechanism in determining the direction of species evolution.
Image sequence-based Financial Time Series forecasting with Self-Supervised Learning
Authors: Li Ningxin , Xu Lidong , Zou Jianke , Por Lip Yee
Published: June 2024

Financial time series are characterized by high volatility and non-linearity, presenting significant challenges for analysis. Traditional statistical methods, such as ARIMA and GARCH, struggle with non-linear data, while machine learning and deep learning techniques can capture intricate price transformations but are often susceptible to overfitting. In addition, the limited parameters of one-dimensional financial time series signals restrict feature representation. To address these challenges, we propose a novel image sequence-based financial time series forecasting with self-supervised learning, employing the custom-designed SPP-CLSTM network for stock trend forecasting. Firstly, we introduce a novel signal transformation strategy to capture and analyze richer multi-scale feature representations in financial time series signals. Specifically, we convert one-dimensional stock price time series data into two-dimensional image sequence representations spanning different time intervals through the Gramian Angular Fields. Moreover, we proposed a self-supervised learning framework, which is instrumental in strengthening the model's capacity to identify intrinsic data relationships, allowing the model to detect underlying patterns and structures while efficiently reducing overfitting. Experimental evaluations on the CSI300E and CSI100E datasets confirm the efficacy of our approach, which accurately predicts high-yield stocks and significantly outperforms industry benchmarks, providing robustness and exceptional performance in dynamic financial data environments.
First principles study of cubic RaHfO3 perovskite for Structural, Electronic, Mechanical, Thermodynamic and Optical properties
Authors: Munshi Md. Rajib , Masud Md Al , Hossain Md. Zakir
Published: June 2024

We have conducted a comprehensive investigation of the RaHfO3 crystal using density-functional theory (DFT). Our study includes analyzing various properties, such as geometrical, electronic, mechanical, thermodynamics and optical properties. To achieve this, we have employed various techniques such as GGA with PBE, RPBE, PBE sol and hybrid B3LYP. The indirect energy bandgap values of RaHfO3 are 2.247 eV, 2.178 eV, 2.095 eV and 3.520 eV, obtained using different computational methods such as PBE, RPBE, PBE sol and B3LYP. Using total and partial density analysis, the atomic orbital nature of the Ra, Hf and O atoms in RaHfO3 was determined. Through the estimation of the Mulliken population charge, a deeper understanding of the bonding characteristics of RaHfO3 has been achieved. After applying the Born mechanical stability criterion, it was found that the RaHfO3 crystal exhibits mechanical stability. An analysis of the ductile strength has been carried out by examining the critical limits of Poisson and Pugh's ratios, revealing the inherent elastic anisotropy characteristics. The thermodynamic stability and thermodynamic states were determined using thermos-physical parameters. Thorough examinations of the optical properties have been carried out using different approaches, leading to definitive conclusions that RaHfO3 demonstrates exceptional effectiveness in absorbing ultraviolet and visible light.
Federated Learning-Based Ransomware Detection via Indicators of Compromise
Authors: Koike Shota , Tanaka Hanako , Maeda Misaki
Published: June 2024

Ransomware attacks have become increasingly prevalent and sophisticated, posing significant threats to data security and organizational operations worldwide. Leveraging a federated learning-based approach, this research presents a novel and significant advancement in ransomware detection by utilizing network and file system indicators of compromise while ensuring data privacy. The methodology involves the decentralized training of machine learning models across multiple clients, which enhances the model's robustness and adaptability to various ransomware attack scenarios. Extensive experiments and evaluations demonstrate the high accuracy, precision, recall, and F1-scores achieved by the proposed model, showcasing its effectiveness in real-world applications. The innovative combination of preprocessing, feature engineering, and sophisticated machine learning techniques within a federated learning framework results in a scalable and privacy-preserving solution capable of addressing the dynamic and evolving landscape of ransomware threats. This study contributes valuable insights into the development of effective ransomware detection systems, emphasizing the importance of collaborative and decentralized learning techniques in enhancing cybersecurity defenses.
MSBoost: Using Model Selection with Multiple Base Estimators for Gradient Boosting
Authors: Agnij
Published: June 2024

Gradient boosting is a widely used machine learning algorithm for tabular regression, classification and ranking. Although, most of the open source implementations of gradient boosting such as XGBoost, LightGBM and others have used decision trees as the sole base estimator for gradient boosting. This paper, for the first time, takes an alternative path of not just relying on a static base estimator (usually decision tree), and rather trains a list of models in parallel on the residual errors of the previous layer and then selects the model with the least validation error as the base estimator for a particular layer. This paper has achieved \textit{state-of-the-art} results when compared to other gradient boosting implementations on 50+ tabular regression and classification datasets. Furthermore, ablation studies show that MSBoost is particularly effective for small and noisy datasets. Thereby, it has a significant social impact especially in tabular machine learning problems in the domains where it is not feasible to obtain large high quality datasets.
PLCE1-AS2 and LINC01605 modulate the function of RPGR in the organelle biogenesis signaling pathway in gastric cancer samples
Authors: AlimardaniBirgani Zeinab , Zamanzadeh Zahra , Abkar Morteza , Azadeh Mansoureh
Published: June 2024

Background: Gastric cancer (GC) represents a significant cause of cancer-related mortality globally, underscoring the pressing need for innovative diagnostic and therapeutic approaches. Long non-coding RNAs (lncRNAs) are increasingly recognized as promising biomarkers due to their pivotal roles in gene expression regulation. This study examines GC specimens' expression and interactions with two novel lncRNAs (PLCE1-AS2 and LINC01605).
Methods: The study utilized microarray analysis (GSE208099) and high-throughput gene expression assessment (ENCORI database) to select and validate novel lncRNAs in GC samples. A lncRNA-mRNA interaction analysis was conducted to identify coding targets of the chosen lncRNAs (lncRRIsearch). The selected lncRNAs' primary target and associated proteins (extracted via STRING) were analyzed using Enrichr to determine related signaling pathways. Validation was further achieved using a qRT-PCR experiment on 20 GC samples and 20 adjacent normal samples.
Results: PLCE1-AS2 and LINC01605 exhibited significantly high expression in GC with log fold changes (logFC) of 2.265 (adj. P-value: 0.00023) and 3.659 (adj. P-value: 0.00266), respectively. Further validation by ENCORI and qRT-PCR experiments corroborated the microarray findings. PLCE1-AS2 and LINC01605 were found to regulate the expression of RPGR mRNA, a crucial protein in the "Organelle Biogenesis and Assembly Signaling Pathway," specifically influencing the "cilium assembly" process. According to receiver operating characteristic (ROC) analysis, PLCE1-AS2 (AUC: 0.7800, p-value: 0.0024) and LINC01605 (AUC: 0.7350, p-value: 0.0110) could serve as potential diagnostic biomarkers for GC.
Conclusion: PLCE1-AS2 and LINC01605 can be promising diagnostic biomarkers for GC. Additionally, these lncRNAs may influence the development of GC through the modulation of organelle biogenesis.
THE ENCOUNTER BETWEEN THE WEST AND ISLAM IN ECOLOGY
Authors: Muhammad Afda Alif , Fazrian Muhammad Ihza
Published: June 2024

This article seeks to discuss the encounter of Arne Naess’s theoretical ecology model and al-Qusyairi's Sufism theory, Ecosufism. To examine their relationship, this article employ Arne Naess's triangulation model of shallow ecology, deep ecology, and complexity, which in Al-Qusyairi’s sufism is referred to as tauḥīd, tazkiyyat an-nafs, and muḥsīn. Thus, this article highlights the sufi figure of akhlāqī (al-Qusyairi) as the subject of philosophical content. This article argues that to lead modern society towards a deeper understanding and practice can be accomplished with spirituality and ecology proceeding together (juxtaposition) in fostering “respectful” behavior toward all creatures. This approach benefits the environment (nature-oriented) and also enriches the individual's spirituality (God-oriented).
TO ASSESS THE KNOWLEDGE AND ATTITUDE TOWARDS CAREER OPTION AFTER BDS AMONGST INTERNEES IN WEST BENGAL : AN ONLINE QUESTIONNAIRE STUDY
Authors:   Senior Lecturer, Department of Conservative Dentistry and Endodontics, Gurunanak Institute of Dental Sciences and Research., Ghosh Sayanti , Bera Maiti Moupriya ,   Senior Lecturer, Department of Conservative Dentistry and Endodontics, Gurunanak Institute of Dental Sciences and Research., Sinha Srijani ,   Clinical Tutor, Department of Conservative Dentistry and Endodontics, Gurunanak Institute of Dental Sciences and Research., Shil Raghunath ,   Reader, Department of Conservative Dentistry and Endodontics, Gurunanak Institute of Dental Sciences and Research., Agarwal Nikita ,   Intern, Gurunanak Institute of Dental Sciences and Research.
Published: June 2024

Introduction: A Graduates career is the course of action they pursue to fulfill their intended employment . The journey from the hallowed halls of dental education to the dynamic realm of professional practice marks a critical juncture in the lives of dental internees. As these individuals transition from the theoretical foundations of their Bachelor of Dental Surgery education to the practical landscape of dentistry, their knowledge and attitudes towards career options become pivotal. Apart from traditional career paths such as private dental practice or working in hospitals there are several alternative and less-known career options that BDS graduates can explore which are yet to be saturated. Before choosing any alternative career path, its essential for BDS graduates to gain additional qualifications or certifications, if required, and network with professionals in their chosen field of interest, for which a tailored support system and guidance program is essential. This study endeavours to explore the multifaceted aspects of the knowledge and attitudes held by dental internees in West Bengal, India, concerning their career choices post-BDS. Objective: To assess the knowledge and attitude toward career option after BDS amongst internees in west Bengal. Material And Method: The study will be conducted among 200 Internees from various dental colleges across West Bengal. For the study a standardized Questionnaire consisting of 12 questions will be formulated in Google Form format and link will be circulated to the Participants. Statistical Analysis: The statistics was generated by Google Forms and tabulated accordingly. Conclusion: By giving students the information and tools they require to make wise career decisions, we can produce a new heneration of dental professionals who are not only clinically skilled but also well-suited to succeed in a variety of professional environments.
THE COLLAPSE OF THE CLEAVAGE BETWEEN NATURALHISTORY AND HUMAN HISTORY
Authors:   Faculty of Letters, Arts and Human Sciences, University of Parakou., Lawani Ayouba
Published: June 2024

This article has endeavoured to challenge theories according to which cosmo-telluric upheavals have blurred the boundaries between natural history and human history to the point of collapsing the old humanist distinction between these two domains. We have argued that humanity is in an unprecedented situation in that it has inaugurated a new history of nature with an apocalyptic perspective, but it is excessive to believe that the conjunction between natural history and human history is a foregone conclusion for ever and ever. We have reached the conclusion that the history of nature does not have a history that is partly entangled with the history of man, but that the action of man affects fundamental processes in nature that were once considered to be able to determine human history, without being determined by it. Previously non-reciprocal action has become reciprocal, but this does not mean the end of natural history and with it the end of the great division. Nature is seriously threatening to determine human history, but this does not break down the old Nature-Culture format. To reach this result, we have used both the direct method of analysis and the historical method.
FINANCING MODEL OF SHARIA ECONOMY-BASED COFFEE AGROINDUSTRY USING DYNAMIC SYSTEM SIMULATION IN BANDUNG DISTRICT
Authors:   Industrial Engineering, Universitas Pancasila, Jakarta, Indonesia., Sundana Sambas , a Sukardi ,   Department of Agro-Industrial Technology, Faculty of Agricultural Engineering and Technology, IPB University, Bogor, Indonesia., b Faqihudin ,   Industrial Engineering, Universitas Pancasila, Jakarta, Indonesia., Raharja Sapta ,   Department of Agro-Industrial Technology, Faculty of Agricultural Engineering and Technology, IPB University, Bogor, Indonesia.
Published: June 2024

West Java Province is one of the producers of export quality Arabica coffee, namely Java Preanger Coffee. The problem that often arises in the agricultural sector is that most farmers do not have the funds to make capital. Another problem in agriculture is capital. This can cause crop failure due to a lack of capital so the process of agriculture is delayed and hampered. The aim of the Islamic financing modelling research is to determine the relationship between variables in the Islamic economic-based financing system as well as a comparison between the application of the concept of profit-sharing margins for mudharabah and musyarakah between farmers and Muhammadiyah Branch Managers (PCM) using the system dynamics method using the Powersim Software. System dynamics are defined to address large-scale and complex systems and understand the relationships among behavior in a given system over time and the underlying structures and decision rules. The sharia economy-based coffee agroforestry financing model results in the application of profit sharing that reflects more justice. The principle of profit sharing carried out by PCM is beneficial for both parties who have achieved the principle of justice, by avoiding things that are unlawful. This can be seen from the results of the profits and losses are not on one side. The simulation results can be used as a consideration for decision making for financing coffee agroforestry in Bandung Regency.
KNOWLEDGE TRANSFER PRACTICES AND STRATEGIES IN HIGHER EDUCATION
Authors:   Faculty of Law and Digital Business, Maranatha Christian University Bandung., Anatan Lina , Bangun Wilson ,   Faculty of Law and Digital Business, Maranatha Christian University Bandung.
Published: June 2024

This study aims to investigate knowledge transfer practices and strategies measured by knowledge vision, leadership, sharing culture, strategies, and IT infrastructures. It also examines how the variables affect organizational performance. By involving 118 respondents collected through an online survey and analyzed using descriptive statistics and multiple linear regression, the study found that knowledge-sharing and IT infrastructure significantly influence organizational performance, while knowledge vision, knowledge leadership, and knowledge-sharing culture do not significantly affect organizational performance. Practices such as public lectures, seminars, workshops, collegial interchange, internships, and research collaborations are considered effective in supporting knowledge transfer activities in higher education. In addition, the knowledge creation process through socialization, externalization, combination, and internalization, and factors such as vision, leadership, culture, and IT infrastructure must be managed properly to support the knowledge transfer process and formulate appropriate strategies.
INFLUENCE OF THE NANOSTRUCTURE OF TANTALUM OXIDE ON THE FLARE CHARACTER OF ITS ELECTROLUMINESCENCEWITH ANODIC-ELECTROLYSIS FORMATION IN CHEMICALLY PURE WATER
Authors:   Kuban State University, Russia, Krasnodar., Boychenko Alexander
Published: June 2024

Theoretical and experimental studies were carried out to identify the reasons for the flash nature of the combustion of electroluminescence (EL) of tantalum oxide (Ta2O5), formed in chemically pure (distilled) water during high-voltage anodization of 1700 s. Nonlinear growth of the Ta2O5 film during this time was established, and a polychrome effect was discovered for its thicknesses from 150 Â± 28 nm to 820 Â± 80 nm. At the same time, EL ignition begins at an oxide thickness of 390 Â± 74 nm, which corresponds to an anodization time of 78 Â± 15 s, and from 968 Â± 185 s until the end of this process, bright EL flashes are observed. Their luminosity can reach 2.8Â·10â€“3 lm/m2. It is shown that the cause of the outbreaks is explosive processes in dynamically changing Ta2O5 pores ranging in size from tens of nanometers to several micrometers and containing gas-discharge plasma from various products of electro- and plasma-chemical reactions with a temperature of the order of 12000 K, created due to Joule heating by the flowing current. It has been established that the formation of the plasma itself occurs as a result of electrical breakdown in pores, the field strength in which can reach the order of 3Â·108 V/m or more.
I. DÜNYA SAVAŞI GÖLGESİNDE EĞİTİM FAALİYETLERİ (1915 KARESİ GAZETESİ HABERLERİNE GÖRE)
Authors: Polat Adem
Published: June 2024

Bu çalışma, 1915 yılında Karesi vilayetinde resmî gazete olarak yayımlanan Karesi gazetesindeki o yıl içerisinde geçen tüm haberler taranarak dönemin eğitim hayatına dair bilgi edinmeyi amaçlamaktadır. Bunun için 28 Aralık 1914 ile 3 Ocak 1916 tarihleri arasında çıkan tüm nüshalar (51 sayı) incelenmiş ve eğitime dair 296 haber tespit edilmiştir. Bu haberler incelemeye tabi tutulmuş ve ana hatlarıyla Eğitim Kurumları, Eğitim İçeriği ve Metodolojisi, Personel İşlemleri, İdari ve Mali İşler, Yaygın Din Eğitimi, Edebiyat ve Müteferrik şeklinde yedi ana kategori belirlenmiş ve bu başlıkları kapsayan haberler ayrı ayrı değerlendirmeye tabi tutulmuştur. Haber içeriklerinden söz konusu tarihlerde Balıkesir’de eğitime dair hummalı bir çalışmanın yapıldığı anlaşılmaktadır. Ayrıca I. Dünya Savaşı’nın bilfiil devam ettiği tarihlere denk gelmesine rağmen eğitim faaliyetlerinin aksamadan yürütüldüğü, tayin, terfi ve atamaların aksatılmadan yerine getirildiği, yoğun bir şekilde mektep inşa faaliyetlerinin devam ettiği ve yeni mekteplerin faaliyete başlatıldığı görülmektedir.
“ADA ŞAİRİ” OLARAK TAHSİN NAHİT
Authors: Çonoğlu Salim
Published: June 2024

1887 tarihinde İstanbul’da doğan Tahsin Nahit’in çocukluk ve gençlik yıllarının büyük bir kısmı, onun şiir, hayal, duygu dünyasında büyük yer kaplayan Büyükada’da geçer. Şiirlerinin büyük bir kısmında Ada’yı arka fon olarak kullanması, Ada’nın etkisinin Tahsin Nahit üzerinde ne derece önemli olduğunu ortaya koymaktadır. Büyükada’da geceleri mehtabı çamlıktan seyretmesi, Ada sahillerinde dolaşıp denizde beyaz perilerin yüzdüğünü tahayyül etmesi, onun şiirine önemli ölçüde ilham kaynağı olmuştur. Sadece sanatında değil, hayatında da Ada’nın rolü o derece büyüktür ki kızı Mina Urgan, hatıralarında, babasının evliliğinde de Adalar şairi olmasının etkisinden bahsetmektedir. Ölümünden sonra da Halid Fahri Ozansoy’un da ifade ettiği gibi, çok sevdiği Büyükada bu genç şairin ebedi istirahatgâhı olmuştur. Bu makalede Türk edebiyatında Ada şairi olarak bilinen Tahsin Nahit’in şiirlerinden hareketle, Ada’nın onun şiirlerine nasıl yansıdığı tespit edilmeye çalışılacaktır.
Mayfly optimization algorithm: a review
Authors: Bogar Mohit N , Shirodkar Ishwar D , Kulkarni Omkar , Jawade Samidha , Kakandikar Ganesh
Published: June 2024

This paper gives a review on the bio-inspired optimization methodology known as mayfly (MA) algorithm in order to resolve issues in optimization techniques. It is a newly formed meta-heuristic optimization algorithm that focuses on the movements of masculine and feminine mayflies. It is encouraged from flying behaviour also the methods of mating in mayflies. With the help of a realistic-world separate flow planning issue along with the coupling behaviour in numerous objective optimizations, the performance of the mayfly algorithm (MA) is well evaluated. Some of the implementations of this algorithm are discussed in this paper: Bearing fault diagnosis based on the mayfly algorithm, optimizing the performance of PEMFC, Covid diagnosis, wind speed optimization, improving the scheduling of solar wind speed using mayfly optimization, detecting fault in the wind turbine gearboxes, patterning in the array antennas with the help of optimization and so on .One of the main advantages of the MA is that it combines the other optimization algorithms namely swarm optimization (PSO) with the evolutionary optimizations (GA). The motion of the mayflies that resemble nuptial dance model along with the arbitrary flight helps in the improvement of the stability within the exploration and exploitation methods. In addition, allows escape from the community peak. All the above work reviewed shows promising results from the algorithm. More work can be carried out using this algorithm in future.
Appraising the eco-health of Tigris River water using pollution indicators and the health risk assessment model
Authors: Ahmed Salwa H. , Abed Mahmood F. , Sharif Salah Farhan A. , Ibrahim Ahmed K.
Published: June 2024

The Tigris River is a major source for supplying water for various purposes (drinking, domestic, industrial, and agricultural) for many cities and villages, and evaluating its water for human use is an important goal. For assessment purposes, nine stations, nine elements, four eco-health pollution indicators, and a health risk assessment model were chosen to evaluate the Tigris River's water environmentally and healthily in three governorates, namely Nineveh, Salah Al-Din, and Baghdad, in April 2023. The results of pollution indicators like the heavy metal pollution index, metal index, synthetic pollution index, and Nemerow Index showed that the Al-Qayyarah and Baiji sites were distinguished by higher values compared to the other stations. High concentrations of cadmium and lead, above the permissible limits for drinking water according to the World Health Organization, have clearly affected the values of pollution indicators. This research showed that there are non-carcinogenic risks to children from drinking water in the Qayyarah and Baiji stations due to the hazard quotient exceeding 1, while there are no risks to adults. Regarding the use of Tigris River water for bathing purposes, the risk quotient value was ,1 for all study stations, indicating that there are no risks to children and adults.
Variability in excitation–emission spectra among wastewater treatment units and applications of fluorescence-based water quality monitoring
Authors: Faizel Haya , Balkhi Syed Arwa A. , Vijayanandan Arya
Published: June 2024

The study assessed the feasibility of fluorescence spectroscopy for characterizing the wastewater of functional wastewater treatment plants (WWTPs) as a real-time monitoring aspect. Peak picking and fluorescence regional integration (FRI) techniques are employed on 3D excitation–emission matrix (EEM) contours in understanding the variations of dissolved organic matter (DOM) of wastewater. Results demonstrate significant reductions in treated wastewater traits, including 94.38% of total suspended solids (TSS), 83.27% of dissolved organic carbon (DOC), and 85.38% of chemical oxygen demand (COD). The microbial analysis detected fecal and total coliforms in the effluent, highlighting the need for continuous monitoring and treatment. However, the biodegradable organic components decrease significantly, with protein-like peaks T1 and B1 intensities declining by 62.17 and 71.7%, respectively, during secondary treatment and further diminishing during tertiary treatment. Conversely, peaks associated with refractory humic and protein-bound components increased after tertiary treatment due to the formation of secondary products. The humification index (HIX) rises from influent to effluent, indicating a reduced carbon-to-nitrogen ratio. At the same time, the biological index (BIX) remained consistent, indicating microbial activity as a significant DOM contributor. The study establishes fluorescence spectroscopy as a promising and rapid monitoring tool for understanding DOM in WWTPs and optimizing treatment effectiveness.
Yoga as a complementary therapy for HIV/AIDS
Authors: Pankaj Patidar  , Pragati Bhutoria
Published: June 2024

HIV/AIDS is a global pandemic. Human immunodeficiency virus (HIV) is an infection that targets the immune system. Acquired immunodeficiency syndrome (AIDS) is the disease’s advanced stage. The first well-documented case of HIV in humans was found in Congo in 1959. During HIV infection, the worst effect is on our body’s immune system due to which the number of CD4+ cells, an important cell in our body, starts decreasing and ultimately this infection takes the form of AIDS. It is possible to avoid this because after this infection, it takes more than 10 years for it to take the form of AIDS. if Yoga therapy is adopted during this period, then the rate of this infection can definitely be reduced. Previous studies showed that Yoga therapy increased the number of vital cells like CD4+. Swami Kuvalayananda introduced Yoga therapy to India in the 1920s. Yoga therapy that involves physical movement or postures, breathing techniques, kriyas and meditation. These practices promote organ system harmony and balance, resulting in improved health and sense of well-being. Various studies have shown that Yoga improved mental health and quality of life of people living with HIV. The study concluded that Yoga therapy can be included as a complementary therapy in the treatment of HIV/AIDS.
Ayurvedic approach of dietary management of Hrudaya Roga - A Review Article
Authors: Temani Rashmi  , Komal Keshwa  , Sharma Surendra Kumar
Published: June 2024

Diet play an important role in our day to day life for maintenance of our health, energy and various activities. It is now agreed that diet governs many situations favouring the onset of many heart diseases. All disease requires modified diet but diet plays a variable role in their cure. All Disease requires modified diet but diet plays a variable role in their cure. To keep good health we must “eat to live and not live to eat”. The concept of Ahara has been given due importance in various text of Ayurveda. Acharaya Sushruta has stated the important factors of healthy living namely strength, complexion and Ojas are dependent on Ahara. It is presumed that all diseases according to Ayurveda are believed to have their root of origin in improper Ahara and hence it is essential to understand the basic concept of Ahara as elaborated in Ayurveda.
Role of Ayurveda medicine in the management of Carcinoma of Breast
Authors: Shripathi Acharya G  , Gopikrishna S. Acharya  , Rajeshwari S. Acharya
Published: June 2024

The incidence of malignant disorders is increasing in modern India. Due to altered lifestyle, faulty food habits intake of carcinogenic drugs, alcohol and tobacco and derangements in hormonal activities, cancers are seen common. Carcinoma of stomach, carcinoma of head of pancreas, carcinoma of breasts, carcinoma of prostate, squamous cells carcinoma of the mouth and tongue, skin carcinoma, osteosarcoma, carcinoma of rectum, Bronchogenic carcinoma are few malignant conditions seen commonly in the society. Surgical excision, Radiotherapy and chemotherapy are practiced in the management of cancer. In Ayurveda, Nidana Parivarjana, use of Vyadhi Pratyanika Aushadhi, Panchakarma therapy, practice of Yogasanas and Pranayama, Pyramid therapy, Pathapathya Prayoga and diet therapies are advocated. Ayurveda provides palliative treatment in this disease. It often improves the quality of life and body strength in these patients. In the review paper, the role of Ayurveda medicine in the management of Carcinoma of breast is discussed elaborately.
Concept and significance of Shatkriyakala
Authors: Geetu Rathour
Published: June 2024

The term Kriyakala refers to the recognition of the stages of a disease progress. This concept is mostly compared with disease pathogenesis. Kriyakala means the time of treatment or interception in the process of disease manifestation. Acharya Susrutha has narrated detailed concept of Shatkriyakala in 21st chapter of Sutrasthana. Shatkriyakala include six stages viz Sanchaya, Prakopa, Prasara, Sthansamshraya, Vyaktavastha and Bhedavastha. Kriya means Action or treatment. Early diagnosis of any disease helps to cure the disease successfully without much discomfort. This is an objective approach of ancient scientists helping for the clinical practice.
Understanding of Krimigranthi w.s.r. to Blepharitis
Authors: Basavaling  , Bhagwat Rohan Gajanan  , Prakruthi G.
Published: June 2024

Ayurveda deals with Ashtangas (8 branches of ayurveda) and Shalakya tantra is one among them. Acharya Sushruta has explained seventy-six eye diseases with their medical and surgical management in detail. Krimigranthi is one among the nine Sandhigata Roga which can be correlated to blepharitis based on the signs and symptomatology. The signs and symptoms include a swelling in the lid margin, lodging of organism in the junction of the eyelids and eyelashes to produce severe itching in the lids. These organisms can move along the eyelid junction which can penetrate and affect the Shuklamandala. Blepharitis is said to be the most common chronic inflammatory disease of the lid margin which can occur at any age. The disease is usually bilateral and become chronic with recurrence and relapse associated with seborrhea of scalp, trichiasis and ectropion. Krimigranthi is said to be a Kaphaja Vyadhi and the management constitutes Swedana, Bhedana, Pratisarana, Rasakriya Anjana and also Nidanaparivarjana, following Pathya-Apathya. The selection of the appropriate treatment depends on the Yukti of the physician and following the appropriate treatment methodology can be helpful to remove the disease from the root and also it is helpful to reduce the recurrence rate.
Role of Dhataki Pushpa in Sandhaan Kalpana
Authors: Joshi Kamakshi , Sanjeev Kumar
Published: June 2024

Woodfordia fruticosa (Dhataki) is a deciduous shrub found abundantly in Arunachal Pradesh, Mizoram and West Bengal. It is commonly known as Fire Flame Bush because of its bright red flowers. Flowering mainly occurs in February to April. These flowers have various medicinal and pharmacological uses. These are helpful in treating diarrhoea, bleeding disorders like menorrhagia, wounds, bleeding piles etc. and have hepatoprotective and antioxidant properties. There is a large demand of these flowers in pharmacies in the preparation of Aasavas and Arishtas as a fermenting agent as they have property of self generating alcohol. The use of Dhataki flowers in the fermentation processes has been documented for the first time in Ashtang Hridya. Acharya Charak has also mentioned Dhataki Pushpa among Aasava Yonis (fermenting agent). It is considered as the backbone of Ayurvedic medicinal industries dealing in fermentation processes and is highly valued in the Indian System of Medicine. So, in this review paper, the role of Dhataki Pushpa in Sandhaan Kalpana has been discussed.[1]
Role of Marma Chikitsa in the management of Anidra (Insomnia) - A Single Case Study
Authors: Aayushi Chouhan  , Rita Marwaha  , Pankaj Gupta  , Nisha Bhalerao  , Swatantra Kumar Chourasia
Published: June 2024

Marma is the vital area of the body. The word Marma comes from the Sanskrit origin word ‘Mri’ meaning death. The Sanskrit phrase ‘Marayanti Iti Marmani’, also means death or serious damage to the body or health after infliction to the point of their situation. Hence these areas are called Marma. Marma Chikitsa focuses on energizing the body to relieve occupational illness and stress-related diseases. Hence the complete knowledge of the basic principles of Marma and its clinical application can play an important role in treatment modalities. Ahara, Nidra, and Brahmacharya are the three factors that play an important role in the maintenance of a living organism. This study focuses on the effectiveness of Marma Chikitsa on Anidra. A 40-year-old female came to the OPD of Pt. Khushilal Sharma Government Ayurvedic College and Hospital, Bhopal (MP) with a complaint of disturbances in the sleep-wake cycle. In this case study effect of Marma Chikitsa in the management of Anidra (insomnia) is evaluated. The patient was treated with Marma Chikitsa for 10 days. The study suggested that Marma Chikitsa may be used for relieving symptoms of Anidra; however, a study on a large population was suggested.