bluuebunny/crossref_metadata_2025 huggingface dataset:
CircHIPK3 knockdown suppresses E2F3 expression to inhibit the viability and promote the apoptosis of lens epithelial cells in age-related cataract by sponging miR-499a-5p
Authors: Han Qichao , Zhang Rong , Ma Lan , Shao Li , Feng Meiyan
Published: June 2021

Introduction

Circular RNA (circRNA) is considered to be a vital regulator of disease progression, including age-related cataract (ARC). However, the molecular mechanism of circHIPK3 in ARC progression has not been fully elucidated.

Material and methods

The expression levels of circHIPK3, miR-499a-5p and E2F transcription factor 3 (E2F3) were measured by quantitative real-time PCR. Cell counting kit 8 assay and flow cytometry were performed to detect cell viability and apoptosis, respectively. Western blot analysis was employed to test the protein levels of apoptosis-related markers and E2F3. Biotin-labeled RNA pull-down assay was used to select miRNAs that could be targeted by circHIPK3, and dual-luciferase reporter assay was performed to confirm the interaction between miR-499a-5p and circHIPK3 or E2F3.

Results

CircHIPK3 is a stable circRNA that is significantly under-expressed in the anterior lens capsule tissues of ARC patients. Knockdown of circHIPK3 suppressed SRA01/04 cell viability and accelerated apoptosis. Moreover, miR-499a-5p could be targeted by circHIPK3, and its inhibitor reversed the effect of circHIPK3 silencing on cell viability and apoptosis. Furthermore, E2F3 was a target of miR-499a-5p, and its overexpression reversed the effect of miR-499a-5p on the viability and apoptosis of SRA01/04 cells. In addition, circHIPK3 positively regulated E2F3 expression by sponging miR-499a-5p.

Conclusions

CircHIPK3 knockdown inhibited viability and enhanced apoptosis of lens epithelial cells to promote ARC progression by regulating miR-499a-5p/E2F3 axis.
Literature Review: Psychosocial Care Perawat Di Ruang Rawat Inap Rumah Sakit
Authors: Elasari Yunina , Hasanah Annida , Alawiyah Tuti
Published: June 2021

Psychosocial care merupakan komponen yang penting dalam memberikan perawatan dengan berfokus kepadapasien yang bertujuan untuk meningkatkan kesejahteraan psikologis dan emosional seperti harga diri, penyesuaianpenyakit, komunikasi, fungsi sosial dan hubungan interpersonal. Penelitian ini bertujuan untuk mengidentifikasidefinisi, hambatan dan upaya dalam meningkatkan psychosocial care perawat di ruang rawat inap berdasarkan studiempiris lima tahun terakhir. Penelitian ini menggunakan pendekatan study literature review dengan menggunakanbeberapa sumber yang dipilih berdasarkan kriteria yang telah ditetapkan peneliti. Dari 10 jurnal yang dilakukankajian literature didapatkan definisi psychosocial care adalah perawatan psikologis, sosial dan spiritual melaluikomunikasi terapeutik dan pendekatan holistik. Hambatan psychosocial care: kurangnya waktu, hambatan bahasa,kurang pengetahuan dan keterampilan, kurang keterlibatan keluarga serta dokumentasi berlebihan. Upaya untukmeningkatkan psychosocial care: pelatihan, dukungan tim profesional dan melibatkan keluarga dalam perawatan.Psychosocial care adalah perawatan yang holistik dan memiliki tantangan tersendiri bagi perawat dalammengaplikasikannya sehingga perlunya upaya untuk mengatasi hambatan dan meningkatkan psychosocial careperawat dengan cara pelatihan psychosocial care, kolaborasi interprofesional dan melibatkan keluarga dalamperawatan
Little epigraphy
Authors: Pitt Robert
Published: June 2021

Most well-known inscriptions are monumental texts carved on stone. In this contribution, on the other hand, we focus on small, often informal texts scratched or stamped on rocks, metal surfaces and pottery. To this type of so-called ‘little epigraphy’ belong for instance graffiti, ostraca, weights and measures, curse tablets, etcetera. Although the texts themselves are usually very short, together they constitute a large corpus.
Over de betekenis van het element ‘algemeen’ in het concept van de algemene vorming
Authors: Rang Adalbert
Published: June 2021

The meaning of ‘general’ in the concept of general education

The author aims at a conceptual-analytical approach. Up to now conceptualization and, above all, the realization of general education remained based on fundamental inconsistencies. Its ‘generality’ was accomplished neither individually nor institutionally. Class- and genderspecific discriminations formed a constitutive part of most concepts and of the educational practice as such. The author then discusses some essential characteristics of a presently relevant concept of general education. He concentrates on the comprehensive, ‘synthesizing’ powers of general education and asks whether the socializing and ‘homogenizing’ (Bourdieu) effects of a truly ‘general’ education can also be regarded as a contribution to autonomizing individuation. The considerations are primarily based on Humboldt and the recent recommendations of the Collège de France (1985).
Twitter based Sentiment Analysis of Impact of Covid-19 on Education Globaly
Authors: Cheeti Swetha Sree , Li Yanyan , Hadaegh Ahmad
Published: June 2021

Education system has been gravely affected due to widespread of Covid-19 across the globe. In this paper we present a thorough sentiment analysis of tweets related to education available on twitter platform and deduce conclusions about its impact on people’s emotions as the pandemic advanced over the months. Through twitter over ninety thousand tweets have been gathered related to the circumstances involving the change in education system over the world. Using Natural language tool kit (NLTK) functionalities and Naive Bayes Classifier a sentiment analysis has been performed on the gathered dataset. Based on the results of this analysis we infer to exhibit the impact of covid-19 on education and how people’s sentiment altered due to the changes with regard to the education system. Thus, we would like to present a better understanding of people’s sentiment on education while trying to cope with the pandemic in such unprecedented times.
Modeling and Verification of ERP Functional Requirements based on Colored Petri Net
Authors: Osman Nafisa , Sahraoui Abd-Elkader
Published: June 2021

The rise of enterprise resource planning (ERP) systems has been a major event in the software industry and it became a solution for most enterprises to manage their data and business processes. Successful ERP implementations can reduce costs by improving efficiency then lead to improved company performance and better competitive edge. Despite these benefits and the age of ERP existing for several decades still high percentage of implementation failures are documented. ERP is packaged software designed by following the best practice from the specific industry to support typical business processes in the entire industrial field, it was designed by ERP vendors and used by the organization which implement it. Since the designer and user are two independent entity misalignments between user’s needs and the software design are often happen. The misalignment define new specific requirements must be embedded into selected ERP. Requirement engineering (RE) is a main part and initial activity of software engineering concern about defines stakeholder requirements, needs and desire. Requirements engineering is the basis for efficient software implementation and quality management. Tools and theories which support RE in general are numerous nowadays; however, the task of providing a tools and theories that specializes in Requirements engineering for Enterprise resource planning systems has been addressed rarely. For that; this paper discusses modelling and verification of ERP functional requirements based on colored Petri nets (CPN) after evaluation of different Business process modelling techniques by using analytical hierarchy process (AHP). CPN considered one of powerful business process modelling techniques and using it help in stakeholder involvement and appropriate organization’s business process representation. The nature of colored Petri nets that help in verification of internal completeness and consistency of ERP functional requirements model.
The Effect of Abusive Supervision and Psychopathy on Counter Productive Work Behavior: The Role of Psychological Capital
Authors: Khattak Pirzada , Rizvi Syed Tahir Hussain
Published: June 2021

Purpose: The purpose of this paper is to scrutinize the influence of Abusive Supervision and Psychopathy on Counterproductive Work Behaviour with moderating role of Psychological Capital in project-based organizations (The construction industry).

Design\Methodology\Approach: Causal model was proposed, Data was collected from 360 employees of different construction projects-based organizations in Islamabad and Rawalpindi region (Pakistan) by using convenience sampling techniques, and adopted structured questionnaires comprising of measuring each variable on a five-point Lickartt scale. SPSS version 22 was used to analyze Reliability, Correlations, and regression.

Originality/value: Different variables have been considered in the relationship with Counterproductive behavior. Abusive supervision and Psychopathy rarely discussed. This study efforts to scrutinize the relationship among AS and CWB, and PSP and CWB, while the moderating role of PSC with the addition of new insights.

Finding: Findings of the current study revealed that there is a positive and significant influence of Abusive Supervision and psychopathy on Counterproductive work bhaviour and a significant moderating role of psychological capital.
The role of sideration in the accumulation of organic matter
Authors:   ООО ", Saakian Alexander ,   БАЛАНС ПРОФИ"
Published: June 2021

Data on the effect of long-term (18 years) use of crop sideration (white mustard), both separately and in combination with straw fertilizer, on the content of organic matter in sod-podzolic soil and crop productivity are presented. In the conditions of an acute shortage of organic fertilizers in agriculture in the central regions of the non-Chernozem zone, a promising and economically profitable form of organic fertilizer is crop crops of sideral crops from the cruciferous family (white mustard, etc.) Keywords: SOD-PODZOLIC SOIL, CROP ROTATION, WHITE MUSTARD, ORGANIC MATTER
RESEARCH OF PROFESSIONAL MOTIVATION OF UNIVERSITY STUDENTS
Authors:   Turan University (Almaty, Kazakhstan), Dautkalieva P. B. , Ormanova Z. K. ,   Turan University (Almaty, Kazakhstan)
Published: June 2021

This article is devoted to one of the most urgent problems of modern students –professional motivation, which significantly affects the future activity of a specialist. Features of formation of professional motivation of students in the course of educational activity in higher education are considered.In turn, professional motivation is an internal driving force that encourages you to develop yourself as a person, master and improve your professionalism. Questions are put forward about what its significance is for the student and how it should be formed in the educational process.The empirical study was conducted on the basis of the Abay Kazakh national pedagogical University. The study involved78 1st-year students of the Institute of pedagogy and psychology. Diagnostic tools were used to assess the formation of students ' professional motivation.The program of empirical research included the results of the following methods: "Research of motivation of professional activity " by K. Zamfir (modified by A. A. Rean) and " Determination of motivation to study" by V. G. Katashev. The results of the analysis revealed high and low levels of professional motivation. Based on the generalization of research data, the author analyzes the features of the emergence and development of professional motivation of students during the training period
A spatially explicit approach to simulate urban heat mitigation with InVEST (v3.8.0)
Authors: Bosch Martí , Locatelli Maxence , Hamel Perrine , Remme Roy P. , Chenal Jérôme , Joost Stéphane
Published: June 2021

Abstract. Mitigating urban heat islands has become an important objective for many cities experiencing heat waves.
Despite notable progress, the spatial relationship between land use and/or land cover patterns and the distribution of air temperature remains poorly understood.
This article presents a reusable computational workflow to simulate the spatial distribution of air temperature in urban areas from their land use and/or land cover data.
The approach employs the InVEST urban cooling model, which estimates the cooling capacity of the urban fabric based on three biophysical mechanisms: tree shade, evapotranspiration and albedo.
An automated procedure is proposed to calibrate the parameters of the model to best fit air temperature observations from monitoring stations.
In a case study in Lausanne, Switzerland, spatial estimates of air temperature obtained with the calibrated model show that the urban cooling model outperforms spatial regressions based on satellite data. This represents two major advances in urban heat island modeling.
First, unlike in black-box approaches, the calibrated parameters of the urban cooling model can be interpreted in terms of the physical mechanisms that they represent; therefore, they can help promote an understanding of how urban heat islands emerge in a particular context.
Second, the urban cooling model requires only land use and/or land cover and reference temperature data and can, therefore, be used to evaluate synthetic scenarios such as master plans, urbanization prospects and climate scenarios.
The proposed approach provides valuable insights into the emergence of urban heat islands which can serve to inform urban planning and assist the design of heat mitigation policies.
A discontinuous Galerkin finite-element model for fast channelized lava flows v1.0
Authors: Conroy Colton J. , Lev Einat
Published: June 2021

Abstract. Lava flows present a significant natural hazard to communities around volcanoes and are typically slow-moving (<1 to 5 cm s−1) and laminar. Recent lava flows during the 2018 eruption of Kīlauea volcano, Hawai'i, however, reached speeds as high as 11 m s−1 and were transitional to turbulent. The Kīlauea flows formed a complex network of braided channels departing from the classic rectangular channel geometry often employed by lava flow models. To investigate these extreme dynamics we develop a new lava flow model that incorporates nonlinear advection and a nonlinear expression for the fluid viscosity. The model makes use of novel discontinuous Galerkin (DG) finite-element methods and resolves complex channel geometry through the use of unstructured triangular meshes. We verify the model against an analytic test case and demonstrate convergence rates of P+1/2 for polynomials of degree 𝒫. Direct observations recorded by unoccupied aerial systems (UASs) during the Kīlauea eruption provide inlet conditions, constrain input parameters, and serve as a benchmark for model evaluation.
The contribution of transpiration, ground evaporation, and canopy evaporation to local and remote precipitation across North America
Authors: Harrington Tyler S. , Nusbaumer Jesse , Skinner Christopher B.
Published: June 2021

Abstract. Land surface evapotranspiration (ET) is a major source of moisture for the global hydrologic cycle. Though the influence of the land surface is well documented, moisture tracking analysis has often relied on offline tracking approaches that require simplifying assumptions and can bias results. Additionally, the contribution of the ET components (transpiration (T), canopy evaporation (C), and ground evaporation (E)) individually to precipitation is not well understood, inhibiting our understanding of moisture teleconnections in both the current and future climate. Here we use the Community Earth System Model version 1.2 with online numerical water tracers to examine the contribution of local and remote land surface ET, including the contribution from each individual ET component, to precipitation across North America. We find the role of the land surface and the individual ET components varies considerably across the continent and across seasons. Much of northern and northeastern North America receives up to 80% of summertime precipitation from land surface ET, and over 50 % of that moisture originates from transpiration alone. Local moisture recycling constitutes an essential source of precipitation across much of the southern and western regions of North America, while remote land surface moisture supplies most of the land-based precipitation across northern and eastern North America. Though the greatest contribution of remotely sourced land ET occurs in the north and east, we find the primary sources of North American land surface moisture shifts seasonally. The results highlight regions that are especially sensitive to land cover and hydrologic changes in local and upwind areas, providing key insights for drought prediction and water resource management.
Maria Paruszewska autorką Hymnu Warmińskiego
Authors: Chłosta Jan
Published: June 2021

Od przeszło 70 lat historycy próbowali ustalić autorstwo słów pieśni O Warmio moja miła, który stał się Hymnem Warmii. Chociaż jeszcze w maju 1920 roku w „Gazecie Olsztyńskiej” wydrukowano pieśń z informacją, że słowa napisała Maria Paruszewska z Poznania, to poddawano w wątpliwość jej autorstwo. Tymczasem to właśnie ona była autorką Hymnu Warmińskiego. Pieśń O Warmio moja miła wydrukowano po raz pierwszy 9 maja 1920 r. wraz z nutami Feliksa Nowowiejskiego, a dziewięć dni wcześniej niż w Olsztynie, w ilustrowanym tygodniku społeczno-narodowym „Praca”, redagowanym wówczas w Poznaniu.
LÓVA: LA ÓPERA COMO VEHÍCULO DE APRENDIZAJE HA VENIDO PARA QUEDARSE Y CRECER
Authors: Moya López Eva
Published: June 2021

LÓVA es el proyecto interdisciplinar que tiene el poder y/o la magia de transformar a cualquier miembro que se beneficie de él. A partir de esta composición dramática y musical se interrelacionan y desarrollan diferentes disciplinas del currículo.

La ópera entra a los centros para modificar desde las raíces el proceso de enseñanza y aprendizaje. Su metodología posee el don de enriquecer los aprendizajes apostando por dotar al alumnado de herramientas para ser competentes a nivel social, moral y cívico. Las prácticas educativas centradas en los alumnos y las alumnas como protagonistas de su aprendizaje son las que van a calar en lo más profundo de su persona despertando inquietudes en su interior hacia el saber, dando sentido a sus horas y años de permanencia en el sistema educativo.
EDUARDO SOLER FIÉRREZ
Authors: Lozano Salinas José María
Published: June 2021

La vida profesional del Inspector de Educación Eduardo Soler Fiérrez, recientemente fallecido, se muestra como un ejemplo y referencia para los docentes en general y para quienes ejercen como Inspectores de Educación.

Su trayectoria personal y laboral le hace protagonista esencial en la evolución y recorrido de nuestro sistema educativo en los últimos cincuenta años, con una intervención como actor imprescindible en su constitución e interpretación.
INSPECCIÓN DE EDUCACIÓN Y EVALUACIONES DE DIAGNÓSTICO: MODELO DE MEJORA CONTINUA
Authors: López García María Teresa
Published: June 2021

La evaluación es un aspecto fundamental para elevar el sistema educativo a cotas mucho más altas en términos de calidad, así como evitar su posible degradación.

Los estudios realizados demuestran que queda mucho camino por avanzar en este sentido, ya que, todavía no hay una verdadera cultura de evaluación y mejora continua en las aulas, identificando en ocasiones evaluar con calificar únicamente.

Las evaluaciones externas actuales son cruciales para el diagnóstico del sistema educativo, proporcionan numerosos indicadores objetivos, pudiendo aplicar las mejoras oportunas, tanto a nivel de Administración como de centros educativos. Sin embargo, a pesar de las claras ventajas que aportan estas evaluaciones, desde sus orígenes han sido ampliamente denostadas por gran parte de la comunidad educativa.

El análisis de los resultados de las evaluaciones externas ofrece a los centros educativos la posibilidad de detectar debilidades y fortalezas para plantear planes de mejora. Sin embargo, algunos centros educativos carecen de la formación y el conocimiento necesario para realizar un análisis adecuado,

Por ello, en este artículo se plantea un modelo que facilitará el asesoramiento que realiza la Inspección de Educación con relación a los procedimientos de mejora continua de los centros educativos después de su participación en dichas evaluaciones.
Blood Flow Quantification in Peripheral Arterial Disease: Emerging Diagnostic Techniques in Vascular Surgery
Authors: Engelhard Stefan , van de Velde Lennart , Jebbink Erik , Jain Kartik , Westenberg Jos , Zeebregts Clark , Versluis Michel , Reijnen Michel
Published: June 2021

The assessment of local blood flow patterns in patients with peripheral arterial disease is clinically relevant, since these patterns are related to atherosclerotic disease progression and loss of patency in stents placed in peripheral arteries, through mechanisms such as recirculating flow and low wall shear stress (WSS). However, imaging of vascular flow in these patients is technically challenging due to the often complex flow patterns that occur near atherosclerotic lesions. While several flow quantification techniques have been developed that could improve the outcomes of vascular interventions, accurate 2D or 3D blood flow quantification is not yet used in clinical practice. This article provides an overview of several important topics that concern the quantification of blood flow in patients with peripheral arterial disease. The hemodynamic mechanisms involved in the development of atherosclerosis and the current clinical practice in the diagnosis of this disease are discussed, showing the unmet need for improved and validated flow quantification techniques in daily clinical practice. This discussion is followed by a showcase of state-of-the-art blood flow quantification techniques and how these could be used before, during and after treatment of stenotic lesions to improve clinical outcomes. These techniques include novel ultrasound-based methods, Phase-Contrast Magnetic Resonance Imaging (PC-MRI) and Computational Fluid Dynamics (CFD). The last section discusses future perspectives, with advanced (hybrid) imaging techniques and artificial intelligence, including the implementation of these techniques in clinical practice.
Cadaveric Model Simulations for Training in Ultrasound-Guided Percutaneous Placement of a Novel Peripheral Nerve Stimulation Electrode
Authors: Gazzeri Roberto , Cesaroni Alessandro , Amorizzo Ezio , Piraccini Emanuele , Micheli Fabrizio , Raggi Massimiliano , Occhigrossi Felice
Published: June 2021

Peripheral nerve stimulation (PNS) electrodes are used to treat intractable painful conditions involving peripheral nerves. Methods for performing PNS continue to evolve, from open surgical to minimally invasive placement of electrodes. A PNS system consisting of subcutaneously implanted leads with an integrated anchor and electrodes, and an external pulse generator to produce peripheral neuromodulation, is now available for use in the clinical setting. This novel system allows either surgical or percutaneous lead positioning, and avoids the use of long leads or extensions crossing the joints, which are exposed to mechanical stress and damage. To identify methods for successfully inserting these electrodes, we investigated if a cadaver model could be an effective educational tool for teaching PNS electrode placement using ultrasound guidance.
Six cadavers were studied in an attempt to find an ideal approach for ultrasound-guided electrode placement into the upper and lower extremities and cervical spine, and to describe the unique anatomy of the peripheral nerves relative to percutaneous stimulation-electrode placement.
The use of cadaveric model simulations offers opportunities to practice percutaneous placement of PNS electrodes under stress-free conditions without patient discomfort, to acquire skill and confidence in performing these surgical approaches. Ultrasound-guided percutaneous placement of PNS electrodes should be learned in a simulation laboratory before such placement is performed in actual patients.
Pneumothorax in Non-Ventilated COVID-19 Patients: A Case Series
Authors: Gharsangi Komal , Bhawani Rajesh , Sandhu Jitender
Published: June 2021

Coronavirus disease 19 (COVID-19) caused by SARS-CoV-2 has spread worldwide resulting in on-going pandemic. Lung is the most common organ involved in COVID-19 with common radiological finding being ground glass opacities in peripheral distribution and lower lobes.1 Pneumothorax is uncommon feature to observe with COVID-19. The exact incidence of this complication is still not known. In a report by Chen et al. 1% (one patient) had a pneumothorax among other radiographic features.2 In a study published by Yang and colleagues in 92 deceased COVID-19 patients, one (1.1%) had a pneumothorax.3 The mechanism of spontaneous pneumothorax in patients with COVID-19 disease is proposed to be related to the structural changes in the lung parenchyma which include cystic and fibrotic changes leading to alveolar tears. In addition to the increase in intrathoracic pressure resulting from prolonged coughing and/or mechanical ventilation.4,5 Pneumothorax further complicates the case of COVID-19. We present two cases of pneumothorax in young males, average height, non-smokers without any pre-existing lung pathology.

Key words: COVID-19, pneumothorax.
Royal Architecture in the Iron Age Levant
Authors: Mumcuoglu Madeleine , Garfinkel Yosef
Published: June 2021

In the Iron Age II, during the 10th to 6th centuries BCE, the local rulers of the Levant developed an elite style of architecture. The aim of this study is to define this phenomenon, summarize the data, and evaluate the appearance and distribution in the Levant of this architectural style. The six prominent characteristics of the royal style are recessed openings of doors and windows, rectangular roof beams, ashlar stone masonry, volute (proto-Aeolic) capitals, window balustrades, and decorated bases.
Development of Intercultural Communicative Competence of Future Specialists in the Field of Information Technologies in the Process of Foreign Languages Learning
Authors: Kostiuk Svitlana S.
Published: June 2021

Intercultural communication practice proves that effective communication with the representatives of different cultures involves not only knowledge of phonetics and lexico-grammatical structure, but the culture of the learned language as well. Therefore, the purpose of the study is to investigate and describe the essence of the term “intercultural communicative competence” and show the materials that promote its development. It is proved that the introduction of competence, communicative, and intercultural-based approaches facilitate the achievement of the set purpose. It has been found that intercultural communicative competence constitutes a complex formation with a lot of components that allow people to choose necessary language and speech means according to the sociocultural context, choose the strategies and tactics of communication to achieve set tasks and mutual understanding with the representatives of other cultures. It is found out that specific principles (dominance of problematic cultural tasks, cultural variability, and cultural opposition) form unbiased attitude towards the multicultural world, teach to perceive and analyse cultural difference, understand the interconnection of language and culture and thus improve the language level. The effectiveness of such methods as conscious-comparative, audiolingual, and role-play has been confirmed. Their introduction promotes meaningful learning and makes the process of intercultural communicative competence development easier. Considering the fact that the basis of intercultural communication is language, culture, and personality, the following components of intercultural communicative competence are identified: value-based, cognitive, effective, culturological. Exercises for intercultural communicative competence development of future specialists in the field of information technologies have been proposed. It is proved that the introduction of mentioned approaches, methods, and tasks has improved the maturity level of intercultural communicative competence. The practical value of the paper is in the fact that obtained results can be used in the process of foreign language teaching in any specialty
Individual-Typological Features of Students’ Psychological Adaptation to the Preparation of External Independent Assessment
Authors: Shtompel Liubov M.
Published: June 2021

Undoubtedly, the present is described by socio-economic, political, and socio-cultural transformations, it is these conditions that create a break with the established axiological, value-related, and normative structures of society. As a result, modern youth is faced with a difficult choice of patterns of behaviour; therefore, the development of a modern personality takes place with a sense of confusion, fear, anxiety, and stress. The most influential stressful situation for high school students is the preparation and pass of an external independent testing. The author proves that psychological stress of any origin prevents quick and constructive decisions, which leads to confusion and cognitive dissonance. Therefore, the author argues that it is necessary to introduce adaptive programmes, trainings that will develop an appropriate level of adaptation, which would facilitate the transition of graduates to a new level of self-growth, as well as feelings such as self-confidence, self-belief, and self-esteem. The purpose of this study was to determine the individual-typological features of psychological adaptation of students to the EIA. To achieve this purpose, methods such as analysis, synthesis, as well as systematisation, generalisation, interpretation, etc. were used. The empirical part of the study used, in particular, hierarchical cluster analysis, the method of group relationships, the method of comparing the mean values of the Student’s T-test for independent samples. It was found that the key to successful psychological adaptation of graduates to the external independent testing is a stable personal potential. Acquired psychological competences will not only help students to effectively demonstrate their knowledge and skills during the exam, but also use them in their future lives. The author argues that it is necessary to provide psychological support to graduating students in preparation for the EIT. Professional psychological help would help reduce emotional stress and anxiety during testing, and help develop the necessary skills to achieve high results
Theoretical Aspects of the Study of the Transformational Potential of Parental Loss for Middle-Aged Adults
Authors: Shchotka Oksana P.
Published: June 2021

The loss of the last of the parents is an understudied and underestimated phenomenon in Ukrainian psychological science in terms of the development of middle-aged adults. The purpose of the study: to identify the role of the loss of both parents in the personal transformation of the adult. To achieve this purpose, the methods of theoretical knowledge were applied: analysis, generalisation, systematization, and interpretation. The methodological framework of the study was formed by the idea of middle age as a time of deep self-cognition, the unification of opposing tendencies, the reaching of mature responsibility, and theoretical ideas of post-traumatic growth. To achieve this purpose, the methods of theoretical cognition were applied: analysis, generalisation, systematization, and interpretation. It was found that the death of the last living parent leads to changes in identity, reassessment of life, relationships, to the use of methods of activity that were previously unavailable. It has been determined that middle-age orphanhood activates specific mechanisms of personality development: loss of existential security (“I am face to face with the world”), actualisation of the fear of death (“I will be the next”). As a result, mature responsibility is born, the fact of the inevitability of personal death is accepted. None of the other normative-age factors have such a strong transformational potential. The most important mediating factor of changes in the adult’s personality is the completeness/incompleteness of the child’s parental relationship with the deceased parents. Incomplete child-parent relationship becomes a source of personal trauma and at the same time contains a powerful resource of personal transformations. The prospect of further study of the long-term consequences of orphanhood in middle age is considered in the empirical verification of the impact of this event on the life and personality of the adult from the subjective standpoint
Primolut - N
Authors: R. Nalini
Published: June 2021

Primolut-N contains norethisterone, which belongs to group of medicines called progestogens, which are female hormones. Primolut-N tablet is used to treat various menstrual problems including painful, heavy, or irregular periods, premenstrual syndrome (PMS) and a condition called endometriosis. It is a man-made version of the natural female sex hormone progesterone. The main ingredient in PrimolutN (Progesterone) is partly converted into estrogen so we should also consider the general warnings.
Design of an Intelligent System for Controlling and Balancing Renewable Energy Flows in an Autonomous Micro-Grid
Authors: Assilevi Kossigan Roland , Ajavon Ayité S. , Adjallah Kondo H.
Published: June 2021

Pooling different renewable energy sources (hydrogen, solar, wind, geothermal, etc.) enables developing a standalone energy micro-grid. The energy flows from these various sources are neither constant nor equivalent. Therefore, control and balancing mechanisms should be established for optimal energy utilization through an intelligent system based on interconnected microcontrollers networked with sensors. Our contribution addresses this issue by proposing an original architecture of an intelligent and distributed control system based on a sensor network and a strategy to share the electric power through the micro-grid. In our work we consider a micro-grid powered by sources of wind turbine, pv panels and battery which energy flows are controlled and balanced through our system depending on power demand of the loads. Alternating Current (AC) bus and Direct Current (DC) bus are tied together by an inverter. A set of microcontroller-sensor-actuators (which we named S.A.D for Sensor/Actuator Device) are deployed at strategic points in the micro-grid providing constantly data from power generated and consumed, equipment health and status. A control algorithm developed in relation to a network control strategy is implemented by combining the performance different microcontroller boards. Relying on existing literature works, a review of solution approaches to the challenging problem, of the power flows balancing between the different energy sources and storage batteries embedding appropriate IoT technologies and exploiting energy big-data platforms, is presented
Nested risks and responsibilities: Perspectives on fertilizer from human urine in two U.S. regions
Authors: Schreiber Tatiana , Opperman Shaina , Hardin Rebecca , Cavicchi Julia , Pallmeyer Audrey , Nace Kim , Love Nancy
Published: June 2021

This paper reports on social research investigating perceptions concerning the diversion of urine from the waste stream and its use as fertilizer in two study regions, New England and the Upper Mid­west. We hypothesized that discomfort or disgust might affect acceptance of such a shift in human “waste” management. However, our findings suggest that a more significant concern of those potentially involved in this process may be distrust of how economic interests influence scientific and technical information. Both physical risks (to the environment and public health) and socio-political risks (to fragile farm economies and consumer communities) play out at individual, household, regional, and global scales. We describe the intersection of these complex understandings as nested risks and responsibilities that must inform the future of urine reclamation. Our respondents' shared concern about environmental risks has already galvanized communities to take responsibility for implementing closed-loop alternatives to current agricul­tural inputs and waste management practices in their communities. Attention to these nested understandings of both risk and responsibility should shape research priorities and foster participatory approaches to urine nutrient reclamation, including strategies for education, planning, regulation, technology design, and agricultural application.
Prone position and APRV for severe hypoxemia in COVID-19 patients: The role of perfusion
Authors: Sato Ryota , Hamahata Natsumi , Daoud Ehab
Published: June 2021

There have been confusion and contradiction on how to best manage patients with acute respiratory failure secondary to Corona virus disease-2019 (COVID-19). Recent report suggested two different phenotypes of patho-physiology (type L and type H). Type L is characterized by low elastance and low ventilation-perfusion mismatch ratio (V/Q), while type H is more consistent with the classic acute respiratory distress syndrome (ARDS) characterized by high elastance, and increased right to left shunt. The role of perfusion deficits has been clearer with the discovery of micro and macro vascular thrombi in the lung vascular endothelium. Prone position has gained interest in research and guidelines as a maneuver capable of improving ventilation and perfusion. Airway pressure release ventilation (APRV) can theoretically improve hypoxemia due to ventilation/perfusion mismatch in patients with COVID-19 compared to other conventional strategies. From this perspective, we may have to consider perfusion as the major problem in the disease process more than just ventilation. More studies are required to explore the role of perfusion and the different ventilatory strategies to best manage those patients. Key Words: airway pressure release ventilation; APRV; prone position; COVID-19; SARS-CoV-2.
Can you calculate the total respiratory, lung, and chest wall respiratory mechanics?
Authors: Shokry Mia , Yamasaki Kimiyo , Daoud Ehab
Published: June 2021

Figure: Waveforms for a patient undergoing mechanical ventilation with volume controlled mode. Tidal Volume of 500 ml, PEEP 15, Constant inspiratory flow of 45 l/min A: Airway pressure in cmH2O, B: Esophageal pressure in cmH2O, C: Trans-pulmonary pressure in cmH2O, D: Flow in l/min, E: Tidal volume in ml Red dashed horizontal line: values at end of expiratory occlusion maneuver, White solid horizontal line: values at end of inspiratory occlusion maneuver, Green dashed horizontal line: values during peak inspiratory pressure.
Fantasy, Fiction, and the Foundations of “Relational Authenticity”: J. M. Barrie'sPeter and Wendyand Søren Kierkegaard'sFear and TremblingRevisited
Authors: Rokotnitz Naomi
Published: June 2021

This article examines notions of authenticity, which have traditionally centered on the individual, and explores instead a view of authenticity that is “reciprocal” (Zahavi 2001; Rokotnitz 2014) and “relational” (Gallagher, Morgan, Rokotnitz 2018). Investigating how children may cultivate a sense of authenticity by engaging in two forms of imaginative projection—make-believe play and fictional stories—I explore how the co-constitution of self and other(s) advances the Existentialist project. Anchoring developmental data, philosophical argumentation, and critical analysis in a literary text written for and about children—J. M Barrie's Peter Pan—I unpack how play and fiction may contribute to authentic self-becoming by fostering social interchange and how this dynamic is made available for interrogation in Barrie's novel. The analysis presented here reveals Wendy to be the heroine of Barrie's novel, reconfiguring its implications for literary scholarship, and also explicates why categories first articulated by Søren Kierkegaard, such as “the single individual” (Fear 67), one's “absolute relation to the absolute” (78), and “witnessing” (104), are still worth pursuing in a post-postmodern twenty-first-century context. Above all, I re-define authentic self-becoming as fundamentally and necessarily relational.
FACTORS AFFECTING BRAND LOYALTY IN THE FOOTWEAR INDUSTRY – “A CASE STUDY OF BANGLADESH.
Authors: Dhar Clinton
Published: June 2021

The Footwear Industry is an important section of the leather industry in Bangladesh. Bangladesh has been ranked 8th in terms of footwear production in the world in 2016. The purpose of this research is to investigate how the respondents are influenced by factors of brand loyalty towards the footwear industry. In order to increase customer satisfaction and drive them to be brand loyalists, marketers are encouraged to develop aggressive marketing programs. The five factors of Brand loyalty are Product Quality, Service Quality, Price, Promotion and Customer Satisfaction. Questionnaires were distributed and self-administered to 30 respondents. Descriptive analysis, Correlation, Model Summary, ANOVA and Coefficient were used in this study. The research results showed that there is a positive and significant relationship between factors of Relationship Quality and Brand loyalty (Product Quality, Service Quality, Price, Promotion and Customer Satisfaction) with the footwear industry.
Aproximación a la representación de personajes de grupos de la diversidad sexual
Authors: Palomino Gámez Sergio , Vázquez Parra José Carlos
Published: June 2021

El objetivo de este artículo ha constituido una aproximación a la manera en que la representación de personajes del colectivo LGBTI+ se ha dado en las últimas décadas en los medios audiovisuales. La intención de este análisis es señalar el impacto que, una representación sesgada o estereotipada puede tener en la constitución de imaginarios incorrectos o limitados que detonan situaciones de discriminación hacia este grupo poblacional. La reflexión se centra en la necesidad de poner atención en la responsabilidad que significa para los generadores de contenidos, el construir y presentar personajes lo más auténticos y apegados a la realidad posible, considerando que esto es parte de la responsabilidad social que tienen hacia sus consumidores.
Actividades que contribuyen al conocimiento de la Historia Local en estudiantes de noveno grado del ESBU Mártires de la Sierpe
Authors: Hernández Torrez Isolidia , Valdivia Valdés Maité Felicia
Published: June 2021

Este artículo ha abordado actividades que contribuyen al vínculo de los conocimientos de Historia Local con los de Historia de Cuba, a tenor de las necesidades objetivas descubiertas en los estudiantes de 9no. grado de la ESBU Mártires de la Sierpe, consecuencia de la aplicación de diversos métodos teóricos, empíricos y matemáticos, reveladores también de las potencialidades que evidencian los educandos de estas edades, en cuyo modelo actual se apoya la investigación. La aplicación de los instrumentos de referencia puso en claro la necesidad de darle tratamiento a la Historia Local insertándola dentro de la Historia Nacional a través del programa de Historia de Cuba de 9no grado a partir de la realización de actividades dinámicas y desarrolladoras, con lo cual se verifica las transformaciones que se decidieron lograr en los indicadores planteados.
Elementos de planeación de las políticas sectoriales del turismo 2018-2019 de México con base en recomendaciones internacionales
Authors: Arjona Granados María Del Pilar
Published: June 2021

La política pública define sus prioridades basadas en requerimientos y demandas sociales. La planeación de políticas públicas en el sector del turismo de la presente administración considera como elementos: integración regional mediante la inclusión y desarrollo social, distribución económica y sustentabilidad. Por su parte, la Organización de Cooperación y Desarrollo Económico propone recomendaciones que se enfocan en mejorar el rendimiento turístico, su competitividad e innovación, mediante la evaluación de las políticas del sector en México. El presente estudio tiene como objetivo general analizar los elementos de planeación de las políticas sectoriales del turismo en consideración con las recomendaciones de organismos internacionales como la OCDE entre otros. La primera parte consiste en análisis de las políticas públicas sectoriales que integran estrategias de regionalización y diversificación de mercados. La segunda analiza el modelo turístico actual que parte de un sentido social e incluyente, con el fin de integrar los beneficios a las comunidades locales. La tercera parte revisala implementación de las recomendaciones emitidas por la OCDE y otros organismos en términos de incrementar la competitividad del sector en el período 2018-2019. La competitividad turística actualmente se refleja en indicadores económicos y de afluencia de turistas, omitiendo elementos de impacto como el ecológico, cultural y social, al margen de las políticas y programas sectoriales, así como de las recomendaciones internacionales.
COVID-19: Ensuring Continuity of Learning During Scholastic Disruption in Tertiary Institutions in Nigeria
Authors: Olawunmi Kunle , Nwamaka Osakwe Grace
Published: June 2021

Issues concerning learning during educational disruption due to the Covid-19 pandemic have been the subject of many excellent journalistic accounts, but there has not been much scholarly output addressing the experience. The need to maintain social distance poses a significant challenge to the international communities particularly between populations, educators and students. Though elicited by COVID-19 pandemic, the focal point of this challenge remains how to offer learning opportunities to students while stakeholders make efforts to contain an awfully virulent pandemic. In Europe and elsewhere, technology has helped with distance learning; assisting individuals on the margins of society and those in formal economy to achieve learning objectives despite a compulsory social distance regime. In other areas of the world such as Africa, correlation between technology and affordability has become a new frontier for continuing education. Encumbrances brought about by COVID-19 have deeply subverted education, state security, sociopolitical stability and economic development, which in turn create or preserve untoward anomaly. In this light, Africa has become the ground zero of disorientation where disorganized criminal groups fester due to poor education and fewer opportunities. The article examines the effect of COVID-19 in the continuing tertiary education relations and concludes that while blended learning is conceivable in Nigeria, rural schools might not benefit from the programme due to truncated development in communication and low level of technology. The use of affordable Internet Radio is thus, recommended for Nigeria.
ON THE SOLUTION OF EQUATIONS WITH NONDIFFERENTIABLE OPERATORS
Authors: ARGYROS IOANNIS K.
Published: June 2021

We approximate solutions_of equations with nondifferentiable operators using the Newton-Kantorovich method and the majorant the­ ory. Under some as easy to verify assumptions as the ones given by Zabrejko and Nguen in [9] we improve their error estimates.
NEW SUFFICIENT CONDITIONS FOR THE APPROXIMATION OF DISTINCT SOLUTIONS OF THE QUADRATIC EQUATION IN BANACH SPACES
Authors: ARGYROS IOANNIS K.
Published: June 2021

Using the "theory of majorants" we provide new sufficient conditions for the approximation of distinct solutions of the quadratic equation in Banach spaces. Our results are applied to a Riccati ordinary differential equation.