bluuebunny/crossref_metadata_2025 huggingface dataset:
Hemodialysis facility star rating affects mortality in chronic hemodialysis patients: a longitudinal observational cohort study
Authors: Park Hayne Cho , Choi Hyung Yun , Kim Do Hyoung , Cho AJin , Kwon Young Eun , Ryu Dong-Ryeol , Yang Ki Hwa , Won Eun Mi , Shin Ji Hyeon , Kim Jinseog , Lee Young-Ki
Published: September 2022

Background: Many countries have their own hemodialysis (HD) quality assurance programs and star rating systems for HD facilities.However, the effects of HD quality assurance programs on patient mortality are not well understood. Therefore, in the present study,the effects of the Korean HD facility star rating on patient mortality in maintenance HD patients were evaluated.Methods: This longitudinal, observational cohort study included 35,271 patients receiving HD treatment from 741 facilities. The fivestarratings of HD facilities were determined based on HD quality assessment data from 2015, which includes 12 quality measuresin structural, procedural, and outcome domains. The patients were grouped into high (three to five stars) and low (one or two stars)groups based on HD facility star rating. Cox proportional hazards model was used to evaluate the effects of star rating on patient mortalityduring the mean follow-up duration of 3 years.Results: The patient ratio between high and low HD facility star rating groups was 82.0% vs. 18.0%. The patients in the low star ratinggroup showed lower single-pool Kt/V and higher calcium and phosphorus levels compared with subjects in the high star rating group.After adjusting for sociodemographic and clinical parameters, the HD facility star rating independently increased the mortality risk(hazard ratio, 1.11; 95% confidence interval, 1.04–1.18; p = 0.002).Conclusion: The HD facilities with low star rating showed higher patient mortality.
COVID-19 Pandemic Inspired Design – An Empirical Study on Maskeeper’s User Experience and Design Ergonomics
Authors: Kee Tris
Published: September 2022

Since early 2020, the COVID-19 pandemic has been affecting all aspects of society, including health care, economy and environment, the Design discipline reacted by inventing many new products to combat the spread of the virus. Amidst all the design innovations created under this “new normal”, Maskeepers® has gained mass popularity in Asia and North America since its release to the market in February 2020. Received both design patent and copyright, this origami-folded mask holder aims to provide convenient and temporary storage to keep surgical masks from cross-contamination and reuse purposes. This paper aims to evaluate the performance of Maskeeper in four parameters, namely material durability, user-friendliness, sustainability and emotional design (MD, UF, SU, ED). By statistically analysing survey data from a sample size of 124 respondent participants, the study validates some critical design attributes that have the most significant impact on user experience, product ergonomics and emotional design. The research also identifies limitations and shortcomings in the first production of Maskeepers and highlights some recommendations for future design development. The research is timely for any designer to consider new COVID-19 innovations and methods of evaluation.
Ergonomics Workspace Design for Work from Home (WFH) during COVID-19 Pandemic Using CATIA V5
Authors: Pal Singh Lakhwinder
Published: September 2022

The Covid-19 pandemic has resulted in enforced scenario of working from home; Most of the IT professional’s corporate office employees are working from home. Therefore, the present study is an attempt for designing office for work from home (WFH). In this study ergonomic analysis of IT based working Professional performed in which a Model created using CATIA V5. The model reveals effects of bad postural working conditions on human body. The results also revealed that mismatch between awkward postures and anthropometric parameters contributed to musculoskeletal disorder. It is necessary to obtain the relevant information or data on task performance, equipment, working posture and environment. Too high workplace results in cramp in shoulder of worker whereas too low workplace may result in backache, therefore, may results in reduced performance. Also as the operator is a highly paid skilled employee, the reduction in performance that can lead to economic consequences for the employer organizations. Therefore, the present study assumes its significance in the pandemic scenario.
Performance of tungro disease resistant rice lines in Lanrang, South Sulawesi, Indonesia
Authors: Mansur Mansur , Muazam Arif
Published: September 2022

Efforts to increase rice production and productivity nationally are still being disturbed by plant pest organisms. One of the diseases that have received serious attention is the tungro disease, which has the ability to attack rice plants in endemic areas. The purpose of this study was to investigate the resistance of several rice lines towards the Lanrang South Sulawesi tungro virus inoculum including morphological characteristics. This study was conducted at the Tungro Disease Research station from June to September 2020. A total of 14 lines were tested for resistance compared to the Tukad Petanu, Tukad Balian, Inpari 8 and Tukad Unda lines against the tungro disease. The rice lines were planted in the form of an augmented design consisting of five blocks. Each block contained three test lines and four comparison varieties, the lines were planted in plots (1 × 5) m, with 25 × 25 cm spacings. The results showed that the population of green leafhoppers at the age of 20 DAP and 30 DAP was found to range from 1 to 95 individuals per line/variety, while the incidence of tungro disease was 1.3 to 11.3% in the three test lines, namely STLRG17 15 LR 1, STLRG17 15 LR 2, and STLRG17 108 LR 1. The highest 1000 seed weight was found in the STLRG17 176 LR 2 line (25.1 g) and the lowest was STLRG17 51 LR 1 (17.6 g). The STLRG17 175 LR 1, STLRG17 176 LR, STLRG17 -175-LR-1, STLRG17-28-LR-1, and STLRG17-26-LR-2  5 lines had a fairly good and consistent appearance at 1000 seed weight, higher yield, productive tillers, plant height, and resistance to tungro disease compared to the comparison varieties.
A Case Study of Community of Inquiry Presences and Cognitive Load in Asynchronous Online STEM Courses
Authors: Faulconer Emily Kaye , Chamberlain Darryl , Wood Beverly L
Published: September 2022

The design and facilitation of asynchronous online courses can have notable impacts on students related to persistence, performance, and perspectives. This case study presents current conditions for cognitive load and Community of Inquiry (CoI) presences in an asynchronous online introductory undergraduate STEM course. Researchers present the novel use of Python script to clean and organize data and a simplification of the instructional efficiency calculation for use of anonymous data. Key relationships between cognitive load and CoI presences are found through validated use of NASA-TLX instrument and transcript analysis of discussion posts. The data show that student presences are not consistent throughout a course but are consistent across sections. Instructor presences are not consistent throughout a course or across sections. The study also explored predominant factors within each presence, confirming previous reports of low cognitive presence in discussions. The highest extraneous cognitive load was reported for understanding expectations and preparing an initial post. These results provide support for improvements to course design and instructor professional development to promote Community of Inquiry and reduce extraneous cognitive load.
Perceptions of and adherence to early COVID-19-related restrictions and associations with substance use among youth in Canada
Authors: Romano Isabella , Patte Karen A. , de Groh Margaret , Jiang Ying , Leatherdale Scott T.
Published: September 2022

Introduction

As a largely social behaviour, substance use may have decreased for some youth overall in Canada during the COVID-19 pandemic; however, continued use may indicate nonadherence to pandemic-related restrictions and social distancing measures. In a sample of Canadian adolescents (aged 12–19 years), our objective was to examine how substance use (cannabis, binge drinking, cigarettes, vaping) is associated with perceptions of, and adherence to, early COVID-19-related public health measures, taking into consideration sociodemographic factors.

Methods

Cross-sectional data were retrieved from online data collected during Year 8 of the COMPASS school-based study, during the early months of the COVID-19 pandemic (May–July 2020) in British Columbia, Ontario and Quebec. We fitted two models using generalized estimating equations to examine how substance use was associated with separate measures of (1) perceptions of, and (2) adherence to early COVID-19 restrictions.

Results

In our sample, 10% of adolescents perceived COVID-19 restrictions as too weak and 14% perceived them as too strict. Nearly half (46%) reported taking restrictions very seriously, and 5% did not take them seriously at all. Binge drinking, cigarette use and vaping were associated with perceptions that restrictions were too strict and with nonadherence. However, adolescents who used cannabis were less likely to perceive COVID-19-related restrictions as too strict.

Conclusion

This study highlights the association of adolescent substance use with perceptions of, and adherence to, COVID-19-related public health restrictions in Canada. Our findings emphasize a need for continual monitoring of substance use behaviours during the COVID-19 pandemic to better characterize adolescent risk and further inform targeted public health strategies accordingly.
The alternative formalism based on the generalized Clifford algebra
Authors: Babaev Alimzhan
Published: September 2022

The article presents the unification of two Maxwell's systems equations (homogeneous and inhomogeneous) within the generalized Clifford algebra. In this new formalism, an electromagnetic current and certain gauges acquire a geometric meaning associated with the properties of space.
De Francia a San Luis Potosí. Circulación de conocimientos y lecturas locales en la segunda mitad del siglo XIX
Authors: Rangel Silva José Alfredo
Published: September 2022

En 1897 Wistano Luis Orozco, abogado experto en litigios por propiedades agrarias, publicó en San Luis Potosí el folleto Las Aguas Subterráneas, un manual para localizar manantiales inspirado en un tratado de 1856 del abate francés Paramelle. Este trabajo explora la circulación de conocimientos y su adaptación en un ámbito local, por medio del análisis de la lectura y recepción crítica del texto francés en España y en México; el folleto de Orozco es una muestra del mundo científico-intelectual de los profesionistas mexicanos de la segunda mitad del siglo XIX. Además de textos de geología e hidrogeología en español, inglés y francés, utilizo publicaciones periódicas de la época como fuentes primarias.
Popularización del futbol en Buenos Aires: “¿Cómo llamaremos a nuestro club?”
Authors: Frydenberg Julio D.
Published: September 2022

El objetivo de este trabajo es adentrarnos en ese proceso de adopción de la práctica del fútbol. Con tal objeto hemos utilizado como base la sección deportiva del diario La Argentina, así como toda una serie de datos emergentes de la llamada “historia tradicional del fútbol argentino” que reflejan los primeros pasos –algo informales– de algunos clubes: la búsqueda se ha centrado en los nombres que les dieron sus jóvenes fundadores. El examen de esos gestos y esas decisiones ayudará a tener una visión más clara de las ideas y sentimientos que movilizaban a esos futbolistas, y podría ser una vía de entrada para testear un universo que es difícil de asimilar en una simple mirada al pasado. Su análisis brinda pistas acerca de los distintos escenarios identitarios nucleantes y el estado mental y emocional de esa juventud porteña, tono que parece haber sobrevivido en el mundo del fútbol hasta hoy, con idas y vueltas, en forma de mareas y de algunos remansos que se resisten a los cambios.
Noción de música en musicoterapia
Authors: Bertoni Santiago
Published: September 2022

El objetivo específico de este artículo apunta a confeccionar una revisión y exposición de las diferentes nociones de música desarrolladas por diferentes escuelas de pensamiento teórico en musicoterapia. Como segundo objetivo, se relacionan aquellas nociones de música en su implicancia en la práctica musicoterapéutica. La primera parte del artículo plantea la complejidad que subyace al momento de definir la música. Para esto, se precisan diferentes posiciones teóricas para desarrollar estas definiciones en la musicoterapia específicamente. La segunda parte presenta una relación entre las nociones de música conceptualizadas por diferentes autores y expone la fundamentación de su utilización en la práctica musicoterapéutica. Para concluir, se observa que, dentro del material teórico, en su mayoría anglosajón, la relación entre noción de música e intervención musicoterapéutica es correspondida. Es decir, las nociones de música en musicoterapia ofrecen la posibilidad de plantear una discusión que potencie la especificidad del proceso musicoterapéutico.
Parâmetros bioquímicos, fisiológicos e produtividade de sorgo granífero irrigado com água salina
Authors: Guimarães Miguel Julio Machado , Simões Welson Lima , Barros Juliane Rafaele Alves , Alberto Keila da Costa , Willadino Lilia Gomes
Published: September 2022

O cultivo do sorgo em ambientes salinos provoca alterações importantes nos processos fisiológicos que são diretamente relacionados com a produtividade das plantas. O estudo objetivou avaliar o efeito da irrigação, com água salina, na produtividade, na atividade enzimática e nas trocas gasosas em variedades de sorgo granífero. Três variedades de sorgo foram submetidas a frações de lixiviação com água salina com condutividade elétrica de 4,19 dS m-1, em esquema de parcelas subdivididas. Foram avaliadas as variáveis distribuição de sais no solo, taxa de fotossíntese e transpiração, temperatura foliar, condutância estomática, atividade das enzimas catalase, ascorbato peroxidase e superóxido dismutase, e produtividade de biomassa da parte aérea. A aplicação de frações de lixiviação com água salina proporciona melhor distribuição dos sais no perfil do solo. Plantas de sorgo submetidas a irrigação com água salina apresentam redução nas trocas gasosas e no estado hídrico das células. A defesa antioxidativa foi ativada em plantas de sorgo cultivadas em ambientes salinos para evitar o acúmulo de espécies reativas de oxigênio, sendo que o sincronismo entre as enzimas refletiu em uma resposta positiva na produtividade das variedades 1011-IPA e Ponta Negra, com aumentos de 126% e 54%, respectivamente, na produtividade de grãos com a aplicação de lâminas de lixiviação. A utilização de água salina com condutividade elétrica média de 4,19 dS m-1 é uma alternativa viável para o cultivo irrigado das variedades 1011-IPA e Ponta Negra em Argissolo Vermelho Amarelo.
Web-Based E-commerce Application at Narmada Furniture Store
Authors: Norhan Linda
Published: September 2022

Narmada Furniture Store is a store engaged in the sale of household furniture items such as tables, chairs, mattresses, cabinets, and others. At the Narmada Furniture Store, the sales system used today is a conventional system, namely the buyer must come directly to the store to see the products offered. At this time the Narmada Furniture Store does not yet have an e-commerce application, so it is difficult to offer products to consumers who are outside the city. In addition, it also results in consumer ignorance of the existence of Narmada Furniture Stores. The selling process of the Narmada Furniture Store is only carried out if there are consumers who come to the store, while many consumers both in Cirebon and outside the city of Cirebon cannot come or do not know the existence of the Narmada Furniture Store.

In analyzing the system, a description of the current system procedures is carried out, so that the system's strengths and weaknesses can be evaluated. In the process of making the system begins with the system analysis stage. Then the process modeling is described using flowmaps, context diagrams, data flow diagrams (Data Flow Diagrams) and Entity Relationship Diagrams (ERD). After the analysis stage is complete, it is continued with the design stage, by making table designs, table relations, program structures, program input and output designs. With this e-commerce application, it is expected to make it easier for consumers to obtain information about product specifications offered by Narmada Furniture Stores. Make it easy for Narmada Furniture Stores in selling their products to consumers who are inside and outside the city of Cirebon. Consumers can find out where the Narmada Furniture store is by using this e-commerce application service and can buy products without having to come to the store. And make it easier for leaders to make decisions based on the output of sales transaction reports and sales charts per month.
Course Scheduling Information System Using Genetic Algorithms
Authors: Wicaksono Freddy , Putra Bayu Permana
Published: September 2022

University X is a private university which has 8 faculties, namely Economics, Engineering, Social Sciences, Faculty of Social and Political Sciences, Fikes, Law, Islam and Vocational Studies. One of the leading study programs at the University X is the Informatics Engineering Study Program at the Faculty of Engineering which is currently experiencing problems when the process of dividing space and hour schedules is still manual.The problems that arise include the accumulation of lecture hours for a lecturer who takes more than one course. Another problem is the disruption of the lecture process at the beginning of the semester due to the tentative scheduling system. The preparation of lecture schedules at the Faculty of Engineering, University X is still done semi-manually using Microsoft Excel, so it will take several days to make a schedule. Meanwhile, making a schedule must be done quickly and optimally because it is used for lecture activities, the solution that can overcome the above problems is by creating a Course Scheduling Information System Using Genetic Algorithms.

The genetic algorithm is one of the most appropriate algorithms used in solving complex optimization problems, which are difficult to do with conventional methods. The nature of genetic algorithms is looking for possibilities from potential solutions to get the optimal for solving problems. The scope of all viable solutions, i.e. the objects between matching solutions, is called the search space. Each point in the search space represents a viable solution.

The limitations of the built problem are: This system is operated by the administrative staff of the study program at the Faculty of Engineering, University X. This system is made using the Codeigniter framework, Responsive Bootstrapping (display) and MySQL as the database and the method used by this system is the genetic algorithm method.

The final result of this research is that it is helpful and easy to apply as a tool in helping the optimization process of lecture scheduling in order to minimize schedule collisions in lectures at the Faculty of Engineering, University X
Analisis Sistem Monitoring Daya dan Kendali Saklar Berbasis ESP8266
Authors: Yuliati Ari
Published: September 2022

The system of remote monitoring electrical and control is a device that was created based on the problem of monitoring the need for electrical power connected to electrical devices and as a development of previous research. This monitoring and control system aims to determine the use of electric power at any time by reading the electric voltage and current with a voltage sensor and a current sensor respectively. The electrical power value that has been detected is forward to firebase and thingspeak, then transmit to the android application. This system is applied for usage monitoring of rooms connected to electrical devices as an indicator of room usage. The results of this system test are the minimum power load that can be detected is 80Watt, some loads still have a high error, but the system is able to detect at a certain distance effectively.
Sistem Monitoring dan Controlling Kualitas Air Serta Pemberian Pakan Pada Budidaya Ikan Lele Menggunakan Metode Fuzzy, NodeMCU dan Telegram
Authors: Maulana Rizky , Kusnadi Kusnadi , Asfi Marsani
Published: September 2022

Catfish farming is one of the fields of business that is still popular today. Cultivation of catfish is a business solution that can be done by anyone. An important factor in the success of catfish farming is to maintain the quality of the pond water in order to keep it good and to provide feed that is carried out regularly. Each type of fish has different characteristics to pond water conditions. In the cultivation of catfish in tarpaulins, the air temperature must be maintained at 20-32 oC, then the pH of the air is good for catfish between 5.5-7.5. If the temperature and pH conditions are outside the specified values, the farmer must replace the fish pond water. Internet of Things (IoT) is a concept where devices can be connected and exchange data with each other through the internet network. In this study, the application of the Internet of Thing (IoT) There are several components used including NodeMCU, pH Sensor, Temperature Sensor, Ultrasonic Sensor, Relay, Pump, Servo Motor and Telegram Bot used for the interface. The fuzzy method used to measure water quality in catfish tarpaulin ponds is based on pH and temperature. The output of this research is a pump control that functions to replace or fill pool water.
The Effect of Online Games on Learning Motivation and Learning Achievement
Authors: Santinah Santinah , Saluky Saluky
Published: September 2022

Technological developments make online games increasingly known throughout the community as a means for entertainment and even serve as a sport. This study aims to determine the effect of online games on learning motivation and student achievement. The results of the study show that at a certain level online games can be used as motivation to learn, but at the level of addiction to online games, it is very disturbing for students in learning achievement.
Analisa Alat Kendali Suhu dan Kelembaban berbasis Arduino Mega 2560
Authors: Yuliati Ari , Gumilar Cecep , Manova Yovi
Published: September 2022

Temperature and humidity control systems are widely applied in agriculture. To increase crop yields and make it easier for agricultural actors, especially in plant cultivation, it is important to innovate in the development of technology that is growing rapidly. This study aims to analyze the level of validity and reliability of temperature and humidity control devices in a cultivation test room based on Arduino Mega 2560 with the help of SPSS. The results of the analysis and test of temperature and humidity control devices, with a maximum coefficient of variation of 1.86% and a minimum reliability coefficient of 0.62.
Analyze the Implementation of the 2013 Curriculum in the Virtual Biology Learning Process for Teachers at a Madrasah Aliyah
Authors: Nasution Siti Hajar , Chastanti Ika
Published: September 2022

Abstract:Implementing virtual learning using technology media is changes. This is a challenge for Biology teachers, especially in implementing the 2013 curriculum. This study analyzed the implementation of the 2013 curriculum in the virtual biology learning process for teachers at a Madrasah Aliyah in Labuhan Batu Regency, North Sumatra. The method used is the descriptive qualitative with subjects in this study were biology teachers who were selected by purposive sampling. Data were collected through interviews and observations. The collected data were then analyzed using the Miles and Huberman model. The results show that the implementation of the 2013 curriculum in the biology learning process during the Covid-19 pandemic has not been maximized. Teachers still experience obstacles in making and implementing RPP activities in online learning. As a result, learning activities are only centered on the teacher.   Abstrak:Penggunaan media teknologi dalam pembelajaran berkembang dengan pesat. Hal ini menjadi tantangan bagi guru Biologi khususnya dalam mengimplementasikan kurikulum 2013. Penelitian ini menganalisis implementasi kurikulum 2013 dalam pembelajaran Biologi secara virtual di salah satu Madrasah Aliyah Swasta di Kabupaten Labuhan Batu Sumatera Utara. Metode yang digunakan adalah kualitatif deksriptif dengan subjek penelitian guru Biologi yang dipilih secara purposive sampling. Data dikumpulkan melalui wawancara dan observasi, kemudian dianalisis menggunakan model Miles dan Huberman. Hasil penelitian menunjukkan implementasi kurikulum 2013 dalam proses pembelajaran Biologi di masa pandemi Covid-19 belum maksimal. Guru masih mengalami hambatan dalam membuat dan melaksanakan kegiatan RPP secara daring. Akibatnya, kegiatan pembelajaran hanya terpusat kepada guru.
Digital transformation of public administration: opportunities and risks
Authors: Kholodenko Yu. A.
Published: September 2022

The article discusses the priorities and socio – economic risks of the digital transformation of public administration. The main approaches to the problem of the use of advanced digital technologies in the activities of state and municipal government bodies aimed at the formation of a modern system digital environment are investigated. The main directions of the digital transition in public administration are considered, which include the digitalization of communications between public authorities, the active introduction of digital technologies into the practice of providing state and municipal services to business structures and households, stimulating the introduction of effective digital solutions as one of the important conditions for social dynamics.

The article identifies the factors and social risks affecting the digital transformation of public administration in the Russian Federation. Among them are the high level of digital inequality, deep social differentiation of regional development, the costly nature of digitalization, risks to the labor market and traditional forms and conditions of employment, problems of adaptation of citizens to the active use of digital technologies in the public administration system, as well as the unconditional provision of citizens' rights and information security in the digital environment. The importance of the course of the Russian state to dynamize the digital transformation of the state and society in the conditions of unprecedented aggravation of international relations in the modern world and tough economic and political sanctions imposed against our country was confirmed.
Thermal Comfort in Indoor Spaces with Radiant Capillary Heaters
Authors: Dzelme Valters , Telicko Jevgenijs , Jakovics Andris
Published: September 2022

Capillary heat exchangers are a great alternative to conventional radiators or electric heaters when used with heat pumps due to larger area and therefore a lower working temperature. In this work, we study thermal conditions in a model room using either capillary or conventional heaters. Experimental measurements in a special test building are used to validate and adjust numerical models. The results show that the vertical temperature distribution is similar with both heating systems, but air flow velocities are considerably higher and floor temperature is less uniform in case of radiator heating. Overall, the capillary system provides more uniform thermal conditions.
PROFESSORES SURDOS NO CONTEXTO ACADÊMICO E SUAS NARRATIVAS SOBRE A ESCRITA ENTRE DUAS LÍNGUAS
Authors: Kist Karoline , Kipper Daiane , Darsie Camilo
Published: September 2022

Questões relacionadas ao domínio das línguas de sinais e da modalidade escrita das línguas orais de diferentes países são tensionadas no contexto dos Estudos Surdos em diferentes situações. Partindo desta questão, pode-se entender que, no Brasil, a aproximação entre a Língua Brasileira de Sinais (Libras) e a Língua Portuguesa gera possibilidades de reflexão que sempre são úteis, tendo em vista que os surdos, usuários da Libras, comunicam-se cotidianamente em uma língua, ao passo que escrevem em outra. No contexto acadêmico, tal situação tem gerado obstáculos, especialmente para docentes surdos que precisam propor, desenvolver e publicar em periódicos relatos de pesquisas, de atividades de extensão e seus resultados. Portanto, este artigo tem por objetivo problematizar as implicações da norma ouvinte nos processos de subjetivação dos professores surdos do Ensino Superior, em especial, no que se refere à produção escrita em Língua Portuguesa. O estudo se apoia no campo dos Estudos Culturais articulados ao campo dos Estudos Surdos e baseia-se em entrevistas realizadas com professores surdos que ministram a disciplina Língua Brasileira de Sinais em universidades federais do Brasil. As narrativas indicam que ocorrem processos de subjetivação acerca do que significa ser docente surdo em contextos universitários e, também, acerca da resistência linguística como uma estratégia de valorização da Libras. Os professores surdos apresentam os limites da escrita por meio da Língua de Sinais e discorrem sobre a importância de se reforçar o valor e o reconhecimento da Língua de Sinais como formas de reinvindicação de novas políticas públicas relacionadas às duas línguas no Ensino Superior.
REPRESENTAÇÃO DE AVÓS MEDIADORES DE LEITURA EM OBRAS DE LITERATURA INFANTIL NO PROGRAMA NACIONAL BIBLIOTECA DA ESCOLA
Authors: De Barros Franciscati Jéssica , Delácio Fernandes Célia Regina
Published: September 2022

Este estudo busca representar, por meio de obras selecionadas pelo Programa Nacional Biblioteca da Escola (PNBE), a relação entre avós e netos que, mesmo em diferentes faixas etárias, conseguem promover elos igualitários estabelecendo uma coeducação de gerações. Para tanto, analisaremos a obra Por parte de pai, de Bartolomeu Campos Queirós (2011), que pretende evidenciar como os personagens idosos/avós têm exercido o papel de mediadores de leitura em relação aos seus netos, e ainda elucidar como acontece esta partilha entre velhos e crianças. Busca, ainda, demonstrar em que medida a narrativa selecionada recupera a voz de velhos e crianças embasando como acontece esta partilha de saber, contudo sem desconsiderar as diferenças existentes na infância e na velhice.
“SER SEM-TERRINHA É BRINCAR, SORRIR, LUTAR!”
Authors: De Sousa Sampaio Barros Leal de Oliveira Júlia Amélia , Oliveira dos Santos Celiane , Penteado Urban Samuel
Published: September 2022

Considerando a íntima relação existente entre a educação e a luta camponesa do Movimento dos Trabalhadores Rurais Sem-Terra, mais especificamente no que se refere ao seu caráter informal, do conhecimento nascido na luta, o presente relato de pesquisa busca externalizar as vozes das crianças sem-terra oriundas do assentamento Osiel Alves, dando destaque para a relação entre “brincar, sorrir, lutar” como parte da identidade sem-terrinha. Metodologicamente, a pesquisa tem a sua base nas conversas/entrevistas realizadas com oito crianças do assentamento, quatro meninas e quatro meninos, em idades diferentes, entre cinco e dez anos. Cabe destacar que a interação com as crianças ocorreu entre os meses de março e abril de 2019.
Urachal sinus in an infant: a case report
Authors: Vescovi Júlia , Doria Clara , Malfussi Hamilton
Published: September 2022

The persistence of the urachus, a tubular structure that connects the bladder to the navel, is an anomaly that consists in its permanence after birth. It can have four different forms and one of the rarest is the urachal sinus. It was reported a 41-day-old female patient with an umbilical scar secretion. Initially, omphalitis was suspected; however, after a diagnostic investigation, it was evidenced, by examining the image, a persistent urachus. Treatment includes surgical correction that can be performed electively.
SOCIAL AND ECONOMIC DEVELOPMENT OF UKRAINE AS THE PRIMARY FACTOR OF MIGRATION TRENDS
Authors:   Chernihiv Polytechnic National University, Povna Svitlana , Rudyak Maryna ,   Chernihiv Polytechnic National University
Published: September 2022

The article systematizes the positive and negative aspects related to migration processes. Based on the analysis of the dynamics of socio-economic development, it is determined that too low a level of investment in the economy leads to such social problems as lack of jobs and rising unemployment. These processes exacerbate migration trends.Social and economic problems originate from the imperfection of the institutional environment. The low level of wages in Ukraine is a consequence of problems related to the efficiency of the economy, which includes the deployment of the re-source curse through the closure of manufacturing, corruption.We also analyzed the situation with employees who currently work for foreign countries, this is especially true of the IT sector, but live and pay taxes in Ukraine. They are characterized by high-level skills and high income levels. With negative expectations for the further development of Ukraine's institutional environment, they may join the ranks of migrants.We came to the following main conclusions: 1) Ukraine'seconomy has stabilized at a very low level, which is unlikely to make Ukraine attractive for the return of its workers in the near future; 2) developed skills of a high level of the population along with the weak capabilities of the institutional environment can add instability in migration processes; 3) the impact on migration processes is a complex issue that affects the foundations of state organization
Uma abordagem geral da Gravidez Ectópica: revisão de literatura
Authors: Amorim Isabelle de Moraes , Gomide Maria Eduarda Marini Amante , Oliveira Marcela Marques de , Azeredo Lucas Marques Luiz , Siqueira Emílio Conceição de
Published: September 2022

Objetivo: Analisar as características da Gestação Ectópica (GE). Revisão bibliográfica: A gravidez ectópica ou gravidez extrauterina é definida como a implantação e o desenvolvimento subsequente do zigoto em um local diferente da cavidade intrauterina. As localizações clássicas para implantação são cervical, intersticial, ístmica, ampular, fimbrial e ovariano, podendo ter também localização abdominal. Globalmente, a gravidez ectópica é responsável por quase 2% de todas as gestações, 0,25-2% de todas as complicações relacionadas à gravidez e 9% de todas as mortes relacionadas à gestação. Para o diagnóstico, a história da paciente é combinada com níveis quantitativos seriados de β-hCG, ultrassonografia e, às vezes, aspiração uterina. Considerações finais: A GE é uma emergência médica que representa 80% das mortes maternas que ocorrem no primeiro trimestre de gestação. Sua apresentação clínica varia de assintomática a dor pélvica aguda acompanhada de sangramento vaginal, podendo apresentar choque. O manejo cirúrgico é indicado para pacientes com contraindicação ao tratamento médico ou tratamento médico falho e para pacientes hemodinamicamente instáveis, enquanto o tratamento clínico é realizado com Metotrexato. Nesse contexto, torna-se essencial o reconhecimento das características da gravidez ectópica a fim de propiciar diagnóstico rápido e tratamento adequado evitando a mortalidade materno-fetal.
Public perception of Invisalign® clear aligner treatment: A cross-sectional survey-based study
Authors: Almotairy Nabeel
Published: September 2022

Objectives:

The demand for clear aligner treatment has increased in recent years. Thus, this study investigated public knowledge regarding Invisalign clear aligner treatment.

Material and Methods:

A web-based survey was administered through different social media platforms covering different aspects of Invisalign treatment, namely: Treatment efficiency, patient discomfort, appliance esthetic attractiveness, oral hygiene maintenance, and treatment aesthetic results. Participants were also asked to outline their perception of Invisalign treatment cost. A Likert-type scale was used to rank the participant responses. Data were analyzed with the Chi-square test and Bonferroni correction for multiple comparisons.

Results:

Out of 934 eligible adult participants, 19.6% were aware of Invisalign. Most of the Invisalign-familiar respondents were unaware of its cost (27.9%) but agree it is generally better (49.7%), requires fewer visits (38.2%), results in shorter treatment duration (39.4%) and reduced teeth discomfort (35%), more esthetically attractive (64%), yields easier oral hygiene maintenance (55.2%), and produces superior esthetic results (43.7%) than traditional braces. In addition, males and average-income participants were more likely to believe that Invisalign treatment produces superior esthetic results than traditional braces (P = 0.0002 and P = 0.002, respectively). Average-income participants also believed that Invisalign treatment was generally better (P < 0.0001). While participants in the age-range 55–64 years strongly believe, it is cheaper (P < 0.0001) than traditional braces.

Conclusion:

This study highlighted the lack of public knowledge about Invisalign treatment. The results also indicated the importance of ensuring public access to reliable information backed up by high-quality evidence.
Understanding Electron Transfer Reactions using Constrained Density Functional Theory: Complications due to Surface Interactions
Authors: Hashemi Arsalan , Peljo Pekka , Laasonen Kari
Published: September 2022

The kinetic rates of electrochemical reactions depend on electrodes and molecules in question. In a flow battery, where the electrolyte molecules are charged and discharged on the electrodes, the efficiency of the electron transfer is of crucial importance for the performance of the device. The purpose of this work is to present a systematic atomic-level computational protocol for studying electron transfer between electrolyte and electrode. The computations are done by using constrained density functional theory (CDFT) to ensure that the electron is either on the electrode or in the electrolyte. The ab-initio molecular dynamics (AIMD) is used to simulate the movement of the atoms. We use the Marcus theory to predict electron transfer rates and the combined CDFT-AIMD approach to compute the parameters for the Marcus theory where it is needed. We model the electrode with a single layer of graphene and methyl-viologen, 4,4'-dimethyldiquat, desalted basic red 5, 2-hydroxy-1,4-naphthaquinone, and 1,1’-di(2-ethanol)-4,4’-bipyridinium were selected for the electrolyte molecules. All of these molecules undergo consecutive electrochemical reactions with one electron being transferred at each stage. Due to significant electrode-molecule interactions, it is not possible to evaluate outer sphere ET. This theoretical study contributes towards the development of a realistic-level prediction of electron transfer kinetics suitable for energy storage applications.
Nanoimpedimetry with plasmonic nanoparticles
Authors: Abayzeed Sidahmed , Fuentes-Dominguez Rafael , Somekh Mike , Clark Matt
Published: September 2022

This paper introduces a new nanosensor that can record electrical currents optically. We demonstrate a robust non-fluorescent approach via chemically stable metallic nanoparticles that promises to enable electrical measurements in complex environments. This is becoming increasingly important in several fields such as electrochemistry, electrophysiology and bioelectricity. The sensing principle is based on the well-known sensitivity of localized surface plasmon resonance to changes in interfacial charge density. Here, we present a new approach that enables quantitative imaging of charge density dynamics at the metal-electrolyte interface of plasmonic nanoparticles. To achieve this, we employed a modelling approach that combines Mie scattering and double-layer capacitor models of the metal-electrolyte interface to convert the intensity of voltage-modulated light scattering by single nanoparticles to charge density modulation. Voltage-modulated single-wavelength micro-spectroscopy was performed to map the charge density modulation of gold nanoparticles attached to a substrate. The reported quantitative imaging method was validated using finite-element models of electrical properties of single plasmonic nanoparticles. Our findings pave the way for rigorous electrical, electrochemical and biochemical sensing using plasmonic nanostructures
Bridging the Gap between the X-ray Absorption Spectroscopy and the Computational Catalysis Communities in Heterogeneous Catalysis: A Perspective on the Current and Future Research Directions
Authors: Rana Rachita , VILA FERNANDO D. , Kulkarni Ambarish , Bare Simon R.
Published: September 2022

X-ray absorption spectroscopy (XAS), (Extended X-ray Absorption Fine Structure (EXAFS) and X-ray Absorption Near-Edge Structure (XANES)), is a key technique within the heterogeneous catalysis community to probe the structure and properties of active site(s) for a diverse range of catalytic materials. However, the interpretation of the raw experimental data to derive an atomistic picture of the catalyst requires modeling and analysis; the EXAFS data are compared to a model and a goodness of fit parameter is used to judge the best fit. This EXAFS modeling can often be non-trivial and time-consuming; overcoming or improving these limitations remains a central challenge for the community. Considering these limitations, this Perspective highlights how recent developments in analysis software, increased availability of reliable computational models and application of data science tools can be used to improve the speed, accuracy, and reliability of EXAFS interpretation. In particular, we emphasize the advantages of combining theory and EXAFS as a unified technique that should be treated as a standard (when applicable) to identify catalytic sites and not two separate complementary methods. Building on the recent trends in the computational catalysis community, we also present a community-driven approach to adopt FAIR Guiding Principles for the collection, analysis, dissemination, and storage of XAS data. Written with both the experimental and theory audience in mind, we provide unified roadmap to foster collaborations between the two communities.
Selective Recognition and Sensing of Biologically Important Phosphates Using Triptycene-Based Anion Receptors
Authors: Kassir Ahmad F. , Lupp Daniel , Grabowski Jakub , Granda Jaroslaw M. , Jurczak Janusz
Published: September 2022

The overarching aim of supramolecular chemistry is to design and synthesize receptors exhibiting selectivity and efficiency comparable to that found in nature in biological receptors and enzymes. Despite the recent progress, we are still far from designing a receptor selective for a given molecular guest. Phosphate-derived anions are particularly interesting molecular targets because of their multiple cellular functions, being constituents of DNA and RNA as well as taking part in the cellular energy conversion mechanisms. Here, we present a systematic investigation of the anion binding properties of triptycene-based anion receptors, and study them in the solid-state as well as computationally using density functional theory(DFT). Titrations under fluorescence control indicate that receptor 1 is highly selective towards monophosphates derived from nucleotides such as AMP, deoxy-AMP, CMP and UMP with binding constant determined to be in the range 6637 – 100000 M-1. Contrary, phosphate anions derived from cyclic AMP and ADP were not bound by receptor 1, as indicated by no change in fluorescence spectra.
Structure-based discovery of multitarget directed anti-inflammatory p-nitrophenyl hydrazones; molecular docking, drug-likeness, in-silico pharmacokinetics, and toxicity studies.
Authors: Babalola Sodeeq , Igie Nosakhare , Odeyemi Isaiah
Published: September 2022

We designed novel p-nitrophenyl hydrazones as multi-target inhibitors of COX-2, 5-LOX, and H+/K+ ATPase in a bid to overcome side effects associated to NSAIDs and coxibs. Specifically, compounds 1-(4-nitrophenyl)-2-[(3,4,5-trimethoxyphenyl)methylidene] hydrazine (3), 4-hydroxy-2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]thiochroman-1,1-dioxide (6), 4-methoxy-2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]thiochroman-1,1-dioxide (8), 2-methyl-6-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]-4-(trifluoromethyl)thiochroman-1,1-dioxide (11), 4-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]benzenesulfonamide (13), 4-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]-3-(trifluoromethyl)benzenesulfonamide (14), 5-methyl-6-{4-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]phenyl}-2,3,4,5-tetrahydropyridazin-3-ol (16), and 5-methyl-6-{4-[(2-(4-nitrophenyl)hydraz-1-ylidene)methyl]phenyl}-4,5-dihydropyridazin-3(2H)-one (17) indicated promise as potent multi-target inhibitors of COX-2, 5-LOX, and H+/K+ ATPase with potential anti-inflammatory activity devoid of adverse effects of NSAIDs. Interactions with important amino acids which are key for ant-inflammatory activity and proton pump inhibition were noticed. All the compounds are less COX-2 selective compared to celecoxib. These compounds in addition have shown druglike physicochemical properties, passed Lipinski’s, Egan’s, Veber’s, Muegge’s and Ghose’s rules for druglike small molecules and orally bioavailable drugs. The compounds also passed golden triangle’s rule for potent and metabolically stable drugs. Also, these compounds passed Pfizer and GSK rules. The compounds also indicated excellent pharmacokinetic profiles complementing their potential anti-inflammatory activity with apparent safety profiles.
MYTHOGONY, OR THE ABILITY TO DISBELIEVE
Authors: Дробышев Виталий Николаевич
Published: September 2022

В статье исследуется вера, взятая в модусе неверия, применительно к современным философиям имманентности (Ж. Делёз, М. Анри, А. Бадью, Ф. Ларюэль). Определяющая это исследование мысль заключается в том, что единственным основанием для признания значимости трансцендирования является само его осуществление верой, тогда как философское или практическое, включая научное, его опровержение, как и утверждение, противоречит его сущности. Философии имманентности, поскольку они отрицают трансцендентное концептуально, то есть без опоры на определяющую их веру, которую они отрицают или не видят, расхоже отождествляя всякую веру с уверенностью, попадают в число философий мифологических, то есть тех, что явно или неявно утверждают ту или иную теорию мифа и вытесняют в область мифического противоречащие им верования и умозрения. Но и философии, утверждающие трансцендентное, точно так же концептуализируют его, оказываясь в итоге столь же мифологичными. Предложенный в статье мифогонический подход, основанный на идее кантовской Критики, направлен на выявление веры, определяющей философское мифопорождение, и существа производимого ею трансцендирования, которое реализует обусловившее его абсолютное экзистенциальное полагание по ту сторону всякой концептуализации.

The article examines faith, taken in the mode of unbelief, in relation to modern philosophies of immanence (J. Deleuze, M. Henry, A. Badiou, F. Laruelle). The thought that determines this study is that the only basis for recognizing the significance of transcending is its very implementation by faith, while philosophical or practical, including scientific, its refutation, like assertion, contradicts its essence. The philosophies of immanence, insofar as they deny the transcendent conceptually, that is, without relying on the faith that defines them, which they deny or do not see, commonly identifying all faith with certainty, fall into the category of mythological philosophies, that is, those that explicitly or implicitly affirm this or that theory of myth and push into the realm of the mythical beliefs and speculations that contradict them. But the philosophies that affirm the transcendent conceptualize it in exactly the same way, ending up just as mythological in the end. The mythogonic approach proposed in the article, based on the idea of Kantian Criticism, is aimed at revealing the faith that determines the philosophical myth generation, and the essence of the transcendence produced by it, which realizes the absolute existential positing that caused it beyond any conceptualization.