bluuebunny/crossref_metadata_2025 huggingface dataset:
The Development of Renewable Energy Sources in the European Union in the Light of the European Green Deal
Authors: Miłek Dorota , Nowak Paulina , Latosińska Jolanta
Published: August 2022

Climate and energy policies are the key areas of the European Union’s development aspirations in the international arena. The European Green Deal sets ambitious new goals in this respect, emphasizing clean energy. The development of the energy sector, relying chiefly on renewable sources, is one of the conditions for the EU to transition to energies that do not produce waste that pollutes or is otherwise harmful to the Earth and human health. This paper assesses the development of renewable sources of energy in the EU and identifies challenges to the realization of the EU’s energy priorities. An analysis of renewable sources of energy in the EU in 2012 and 2020 is the prime method. The generation of primary energy from renewable sources, the share of energy from renewable sources in the final energy consumption, the structure of energy generation from renewable sources, and the share of energy from renewable sources in the energy used by the transport sector are discussed. Secondary data are employed, made available by Eurostat and Statistics Poland. To reach the objective of the study, Z. Hellwig’s taxonomic method is applied to assess the development of renewable energy sources (RES). Cluster analysis (Ward’s agglomerative clustering method) is additionally used for separation of objects and member states that are similar with regard to the phenomenon reviewed. Particular attention is paid to the challenges that societies and economies face in view of the assumptions of the EU’s new Green Deal, which envisages a balancing of CO2 emissions and absorption. This analysis discovers varied progress on the development of RES in the member states, posing a threat to the European community’s aspirations.
Home Energy Upgrades as a Pathway to Home Decarbonization in the US: A Literature Review
Authors: Less Brennan D. , Casquero-Modrego Núria , Walker Iain S.
Published: August 2022

This work aims to characterize how home energy upgrade projects and programs in the US have evolved over the past decade. It also identifies what changes are needed to drive expansion of the US energy retrofit market in such a way that addresses carbon emissions from buildings, improves resilience and upgrades the housing stock. This review focuses on whole-home energy upgrades, targeting deep energy retrofit savings of >30%. The topics we cover include trends in home electrification, US and European home energy upgrade programs, energy upgrade measure costs, business economics, and health effects. Key changes in project design noted in this review include: (1) the electrification of dwellings with rapidly improving heat pump systems and low-cost solar photovoltaic technology; and (2) a shift away from high-cost building envelope strategies and towards more traditional home performance/weatherization envelope upgrades. Promising program design strategies covered include: (1) end-use electrification programs; (2) novel financing approaches; (3) the use of carbon-based program and project metrics; and (4) “one-stop shop” programs. Based on the existing market barriers, we suggest that the industry should adopt new project performance metrics. Additionally, market drivers are needed to spur widespread energy upgrades in the US housing stock. Costs must be reduced, and projects designed to appeal to homeowners and contractors.
In-Situ LID and Regeneration of Al-BSF Solar Cells from Different Positions of a B-Doped Cz-Si Ingot
Authors: Ding Siqi , Yang Chen , Yuan Shuai , Ai Bin , Qin Cheng , Li Zhengke , Zhou Yecheng , Sun Xiaopu , Yang Jianghai , Liu Quan , Liang Xueqin
Published: August 2022

In this paper, five groups of industrial aluminium back-surface-field (Al-BSF) solar cells were made from silicon wafers from different locations of a B-doped Czochralski silicon ingot. Then, we performed the first LID (45 °C, 1 sun, 12 h), regeneration (100 °C, 1 sun, 24 h), and second LID (45 °C, 1 sun, 12 h) treatments on the cells, and measured the in-situ changes of their I-V characteristic parameters by using an I-V tester during the experiment. The cells were also characterized by Suns-Voc measurement, full-area light beam induced current scanning, and external quantum efficiency measurement at the four breakpoints of treatments (before and after the first LID, after regeneration and the second LID). It was found that the LID and regeneration of the Al-BSF solar cells can be explained by the LID and regeneration reaction of B-O defects and the LID caused by dissociation of Fe-B pairs. After regeneration, the relative decay rate of efficiency decreased from 2.75–3.8% during the first LID to 0.42–1.23% during the second LID, indicating that regeneration treatment (100 °C, 1 sun, 24 h) can improve the anti-LID ability of Al-BSF solar cells.
A Substation-Based Optimal Photovoltaic Generation System Placement Considering Multiple Evaluation Indices
Authors: Leou Rong-Ceng
Published: August 2022

The placement of the photovoltaic generation system (PVGS) and operation of the on-load tap changer (OLTC) should have great impacts on the system loss and voltage quality, which are the main concerns of the distribution operator. Considering these multiple evaluation indices and other constraints, this paper proposed a substation-based optimal PVGS placement and OLTC operation model. The objective function that was used to evaluate the optimal PVGS placement and OLTC operation consists of a minimization of system loss and voltage quality. The model’s constraints contain the voltage and line flow limits, voltage deviations, voltage unbalance, etc. Uncertainties of the load and irradiance are also included in the model. A nondominated sorting genetic algorithm II (NSGA II) is used to solve this multi-objective optimization problem. Comparisons of the substation-based and feeder-based planning are also studied in this paper. The test results demonstrate the substation-based planning could obtain a better solution.
Influence of Ozone and Drought on Tree Growth under Field Conditions in a 22 Year Time Series
Authors: Eghdami Hanieh , Werner Willy , De Marco Alessandra , Sicard Pierre
Published: August 2022

Studying the effect of surface ozone (O3) and water stress on tree growth is important for planning sustainable forest management and forest ecology. In the present study, a 22-year long time series (1998–2019) on basal area increment (BAI) and fructification severity of European beech (Fagus sylvatica L.) and Norway spruce (Picea abies (L.) H.Karst.) at five forest sites in Western Germany (Rhineland Palatinate) was investigated to evaluate how it correlates with drought and stomatal O3 fluxes (PODY) with an hourly threshold of uptake (Y) to represent the detoxification capacity of trees (POD1, with Y = 1 nmol O3 m−2 s−1). Between 1998 and 2019, POD1 declined over time by on average 0.31 mmol m−2 year−1. The BAI showed no significant trend at all sites, except in Leisel where a slight decline was observed over time (−0.37 cm2 per year, p < 0.05). A random forest analysis showed that the soil water content and daytime O3 mean concentration were the best predictors of BAI at all sites. The highest mean score of fructification was observed during the dry years, while low level or no fructification was observed in most humid years. Combined effects of drought and O3 pollution mostly influence tree growth decline for European beech and Norway spruce.
Functional Analysis of Lactic Acid Bacteria and Bifidobacteria and Their Effects on Human Health
Authors: Dueñas María Teresa , López Paloma
Published: August 2022

Many lactic acid bacteria (LAB) and Bifidobacteria are beneficial components of human, animal, foods, and beverage microbiota [...]
Effects of Naringin on Postharvest Storage Quality of Bean Sprouts
Authors: Yang Xufeng , Zhao Yihan , Gu Qiuming , Chen Weiling , Guo Xinbo
Published: August 2022

This study investigated the effects of naringin on soybean and mung bean sprouts postharvest quality. It was found that naringin could maintain the appearance and quality of soybean sprouts and mung bean sprouts during a 6-day storage period as well as delay the occurrence of browning in mung bean sprouts and soybean sprouts. The optimal application rate of naringin was 50–100 μg/mL, which could effectively inhibit the activity of polyphenol oxidase (PPO) and peroxidase (POD) in bean sprouts and increase the ascorbic acid content, where this inhibition response to the browning of mung bean sprouts and soybean sprouts was significantly reduced. Naringin treatment increased gallic acid and p-coumaric acid content in mung bean sprouts as well as the daidzin and rutin content in soybean sprouts, which was also reflected in the improvement of antioxidant activity. The binding of naringin with PPO and POD was analyzed with molecular docking, naringin, and PPO had a lower binding energy (−1.09 Kcal/mol). In conclusion, naringin application in postharvest preservation of mung bean sprouts and soybean sprouts can maintain favorable consumer quality.
Driver’s Perceived Satisfaction at Urban Roundabouts—A Structural Equation-Modeling Approach
Authors: Damaskou Efterpi , Kehagia Fotini , Karagiotas Ioannis , Anagnostopoulos Apostolos , Pitsiava-Latinopoulou Magdalini
Published: August 2022

In recent years, the use of roundabouts in road networks has reflected a sustainable and modern solution for traffic intersections. Their implementation, integrated design, and proper evaluation are a necessity to achieve their beneficial results. According to the latest edition of the Highway Capacity Manual (HCM) and the Highway Capacity and Quality Service (HCQS), a comprehensive evaluation of a roundabout is based on the interchangeable use of the LOS (level of service) and QOS (quality of service). Both manuals describe the LOS criteria, which are the same as those currently used for unsignalized at-grade intersections, while the QOS methodological description and criteria are not specifically defined. The quality of service, which corresponds to road users’ perceived satisfaction, is determined by identifying and evaluating certain factors that have an impact on users. While the previous work on evaluating the quality of roundabouts is limited, this work aimed to present and evaluate the concept of QOS for urban roundabouts in Greece and to assess the factors that affect drivers’ perceived feeling of comfort. The methodology used for the research, included data collection via an on-line questionnaire addressed to the users of the Greek road network and a statistical analysis based on the performance of six latent variables named quality components (exploratory factor analysis). A structural equation model (SEM) was used to determine the causal relationship between primary factors and quality components. It was noted that the SEM cannot predict the travel behavior but it has ability to express relationships between unobserved and observed variables. The results of the revealed model are of great value for the development of: (a) a comprehensive conceptual framework of the QOS and (b) a critical analysis of the parameters that should be considered for the assessment of the QOS of a roundabout. Identifying the factors that influence road users’ perception in terms of safety and comfort (quality of service) leads to a better knowledge and understanding of the road network characteristics that are important to road users and that influence their behavior and level of satisfaction.
Applications and Mechanisms of Stimuli-Responsive Hydrogels in Traumatic Brain Injury
Authors: Li Xingfan , Duan Linyan , Kong Mingyue , Wen Xuejun , Guan Fangxia , Ma Shanshan
Published: August 2022

Traumatic brain injury (TBI) is a global neurotrauma with high morbidity and mortality that seriously threatens the life quality of patients and causes heavy burdens to families, healthcare institutions, and society. Neuroinflammation and oxidative stress can further aggravate neuronal cell death, hinder functional recovery, and lead to secondary brain injury. In addition, the blood–brain barrier prevents drugs from entering the brain tissue, which is not conducive to the recovery of TBI. Due to their high water content, biodegradability, and similarity to the natural extracellular matrix (ECM), hydrogels are widely used for the delivery and release of various therapeutic agents (drugs, natural extracts, and cells, etc.) that exhibit beneficial therapeutic efficacy in tissue repair, such as TBI. Stimuli-responsive hydrogels can undergo reversible or irreversible changes in properties, structures, and functions in response to internal/external stimuli or physiological/pathological environmental stimuli, and further improve the therapeutic effects on diseases. In this paper, we reviewed the common types of stimuli-responsive hydrogels and their applications in TBI, and further analyzed the therapeutic effects of hydrogels in TBI, such as pro-neurogenesis, anti-inflammatory, anti-apoptosis, anti-oxidation, and pro-angiogenesis. Our study may provide strategies for the treatment of TBI by using stimuli-responsive hydrogels.
Biopolymer Lipid Hybrid Microcarrier for Transmembrane Inner Ear Delivery of Dexamethasone
Authors: Dindelegan Maximilian George , Pașcalău Violeta , Suciu Maria , Neamțu Bogdan , Perde-Schrepler Maria , Blebea Cristina Maria , Maniu Alma Aurelia , Necula Violeta , Buzoianu Anca Dana , Filip Miuța , Csapai Alexandra , Popa Cătălin
Published: August 2022

Dexamethasone is one of the most often used corticosteroid drugs for sensorineural hearing loss treatment, and is used either by intratympanic injection or through systemic delivery. In this study, a biopolymer lipid hybrid microcarrier was investigated for enhanced local drug delivery and sustained release at the round window membrane level of the middle ear for the treatment of sensorineural hearing loss (SNHL). Dexamethasone-loaded and dexamethasone-free microparticles were prepared using biopolymers (polysaccharide and protein, pectin and bovine serum albumin, respectively) combined with lipid components (phosphatidylcholine and Dimethyldioctadecylammonium bromide) in order to obtain a biopolymer–liposome hybrid system, with a complex structure combining to enhance performance in terms of physical and chemical stability. The structure of the microparticles was evaluated by FTIR, XRD, thermal analysis, optical microscopy, and scanning electron microscopy (SEM). The encapsulation efficiency determination and the in vitro Dexamethasone release study were performed using UV-Vis spectroscopy. The high value of encapsulation efficiency and the results of the release study indicated six days of sustained release, encouraging us to evaluate the in vitro cytotoxicity of Dexamethasone-loaded microparticles and their influence on the cytotoxicity induced by Cisplatin on auditory HEI-OC1 cells. The results show that the new particles are able to protect the inner ear sensory cells.
Increasing the Hydrophobic Component of Poloxamers and the Inclusion of Salt Extend the Release of Bupivacaine from Injectable In Situ Gels, While Common Polymer Additives Have Little Effect
Authors: Abdeltawab Hani , Svirskis Darren , Hill Andrew G. , Sharma Manisha
Published: August 2022

Various strategies have been applied to reduce the initial burst of drug release and sustain release from poloxamer-based thermoresponsive gels. This work focussed on investigating different formulation approaches to minimise the initial burst of release and sustain the release of the small hydrophilic drug bupivacaine hydrochloride from poloxamer-based thermoresponsive gels. Various in situ gel formulations were prepared by varying the polypropylene oxide (PPO)/polyethylene oxide (PEO) ratio and by adding additives previously described in the literature. It was observed that increasing the PPO/PEO ratio from 0.28 to 0.30 reduced the initial burst release from 17.3% ± 1.8 to 9.1% ± 1.2 during the first six hours and extended the release profile from 10 to 14 days. Notably, the inclusion of sodium chloride (NaCl 0.4% w/w) further reduced the initial burst release to 1.8% ± 1.1 over the first 6 h. Meanwhile, physical blending with additive polymers had a negligible effect on the burst release and overall release profile. The findings suggest that extended release of bupivacaine hydrochloride, with reduced initial burst release, can be achieved simply by increasing the PPO/PEO ratio and the inclusion of NaCl.
The Contribution of Genetics to Muscle Disuse, Retraining, and Aging
Authors: Sirago Giuseppe , Picca Anna , Giacomello Emiliana , Marzetti Emanuele , Toniolo Luana
Published: August 2022

Genetic background may partly explain differences in muscle responses to internal or external stimuli. Muscle disuse involves various degrees of skeletal muscle atrophy due to inactivity and mechanical unloading. Whether and to which extent genetic background impacts disuse atrophy and retraining in individuals of different ages are currently unclear. Here, we provide a brief overview of relevant literature on the contribution of genetics to muscle disuse, retraining, and aging, and offer a perspective on unanswered questions on the subject that may open new venues for research.
Comparative Transcriptome Profiling Reveals Potential Candidate Genes, Transcription Factors, and Biosynthetic Pathways for Phosphite Response in Potato (Solanum tuberosum L.)
Authors: Dormatey Richard , Qin Tianyuan , Wang Yihao , Karikari Benjamin , Dekomah Simon Dontoro , Fan Youfang , Bi Zhenzhen , Yao Panfeng , Ali Kazim , Sun Chao , Bai Jiangping
Published: August 2022

The study was conducted with C31 and C80 genotypes of the potato (Solanum tuberosum L.), which are tolerant and susceptible to phosphite (Phi, H2PO3), respectively. To decipher the molecular mechanisms underlying tolerance and susceptibility to Phi in the potato, RNA sequencing was used to study the global transcriptional patterns of the two genotypes. Media were prepared with 0.25 and 0.50 mM Phi, No-phosphorus (P), and 1.25 mM (phosphate, Pi as control). The values of fragments per kilobase of exon per million mapped fragments of the samples were also subjected to a principal component analysis, grouping the biological replicates of each sample. Using stringent criteria, a minimum of 819 differential (DEGs) were detected in both C80-Phi-0.25_vs_C80-Phi-0.50 (comprising 517 upregulated and 302 downregulated) and C80-Phi-0.50_vs_C80-Phi-0.25 (comprising 302 upregulated and 517 downregulated) and a maximum of 5214 DEGs in both C31-Con_vs_C31-Phi-0.25 (comprising 1947 upregulated and 3267 downregulated) and C31-Phi-0.25_vs_C31-Con (comprising 3267 upregulated and 1947 downregulated). DEGs related to the ribosome, plant hormone signal transduction, photosynthesis, and plant–pathogen interaction performed important functions under Phi stress, as shown by the Kyoto Encyclopedia of Genes and Genomes annotation. The expressions of transcription factors increased significantly in C31 compared with C80. For example, the expressions of Soltu.DM.01G047240, Soltu.DM.08G015900, Soltu.DM.06G012130, and Soltu.DM.08G012710 increased under P deficiency conditions (Phi-0.25, Phi-0.50, and No-P) relative to the control (P sufficiency) in C31. This study adds to the growing body of transcriptome data on Phi stress and provides important clues to the Phi tolerance response of the C31 genotype.
Exploring Psychological Needs and Burden of Care in Parents of Children with Hemato-Oncological Diseases
Authors: Benedetto Loredana , Marino Irene , Ronco Francesca , Iaria Grazia , Foletti Luisa , Ingrassia Massimo
Published: August 2022

Caring for a child with an acute/life threatening disease exposes parents to multiple stressors and challenges, resulting in a physical and psychological burden. Parents experience many health-related issues and worries that often remain underestimated. The aims of the study were: (a) to explore the associations between needs/disease-related issues and burden in parents of children with leukemia or Hodgkin’s disease; (b) to estimate predictors of parents’ burden using a stepwise linear regression analysis. Children (N = 33) followed an active therapy protocol (48.5%), or they were off therapy (51.5%). Forty-four parents completed surveys on caregiver burden levels and needs to cope with the child’s illness. Parental factors impacting burden (personal resources, loss of control, depression) and child’s quality of life (QoL) were also assessed. Among the needs, information about the illness/resources were the most urgently expressed by parents, followed by reassurance against fears for the child’s development and future well-being. Parents reported severe (27.3%) and moderate (22.7%) burden, with a higher percentage of caregivers with severe burden in the off-therapy phase (18.2%) than in the active-therapy phase (9.1%). The child’s decreased physical QoL and parent’s loss of control predicted higher levels of burden. The implications for supportive interventions aimed at responding to parental needs and preventing caregiver burden are discussed.
Modeling Chemical Tests and Fiber Identification of Paper Materials Using Principal Component Analysis and Specular Reflection FTIR Data
Authors: Wertz Julie H. , McClelland Arthur A. , Mayer Debora D. , Knipe Penley
Published: August 2022

Paper materials and works of art on paper such as drawings, watercolors, prints, books, and manuscripts represent a large portion of museum, archive, and library collections. However, paper materials are infrequently the subject of technical studies due to inherent limitations in their analysis such as the fragility of the paper substrate, a lack of suitable sampling opportunities, and the presence of mixed, but chemically similar cellulosic materials. The application of principal component analysis (PCA) modeling to specular reflection FTIR data has the potential to provide a non-invasive means of analysis for major and minor components in paper materials. Using known study collection objects, PCA models distinguishing paper sizing materials and fiber types based on specular reflection FTIR data were successfully demonstrated thus providing a plausible alternative method for the identification of paper materials in collection objects without the need for destructive testing or sampling of the object.
River Beaches in Russian Cities: Examples of Soviet Legacy
Authors: Mikhailenko Anna V. , Mamiev Mergen B. , Hanow Toyly , Kashkovskaya Ilona M. , Yashalova Natalia N. , Ruban Dmitry A.
Published: August 2022

The diversity of urban heritage is determined by some national peculiarities of the development of cities and towns. In Russia, river beaches are common recreational elements of urban environments. Representative examples of such beaches from two cities, namely Rostov-on-Don and Cherepovets, are examined. This study utilizes both a qualitative approach for argumentation of heritage value and a semi-quantitative evaluation of aesthetic properties. It is argued that the urban river beaches are linked closely to the cities’ identities. They were created in the Soviet times when significant attention was paid to healthy lifestyle and rational planning in growing and industrialized urban areas. Two main findings are the potential historical heritage value of the urban river beaches of Russia, including two examples considered in this study, and their significant appeal to the visitors’ sense of beauty. Although Rostov-on-Don and Cherepovets represent very different natural and socio-economical environments, their river beaches are important in regard to the representation of the cities’ identities and aesthetics. This importance is a bit higher in the case of Rostov-on-Don. It is generally concluded that river beaches in Russian cities constitute potential, country-specific heritage, which seems to be a part of the Soviet legacy. Creating their national catalogue with GIS technologies is desirable.
Key Determinants of the Physiological and Fruit Quality Traits in Sweet Cherries and Their Importance in a Breeding Programme
Authors: Devasirvatham Viola , Tan Daniel K. Y.
Published: August 2022

Australia produces high-quality sweet cherries and generates revenue from local and export markets. Due to increased demand in the markets, the area of sweet cherry production has increased in Australia. Sweet cherry breeding and production have challenges such as self-incompatibility genotypes and phenotyping of agronomic, physiological, and quality traits. Understanding these traits and their interaction with environmental factors would increase production and provide better economic returns for the industry. This review paper covered the challenges of current sweet cherry production, breeding efforts, the basis for understanding of plant traits, the influence of environmental factors on the traits, and opportunities for new sweet cherry breeding in the future. The period of flowering and maturity along with firmness of the fruit are key traits in cherry production. Breeding techniques such as haplotype breeding will contribute to improving breeding efficiency and deliver better cultivars of sweet cherry.
Heavy Study Investment: An Analysis of the Defense Mechanisms Characterizing Studyholism and Study Engagement
Authors: Loscalzo Yura , Giannini Marco
Published: August 2022

Defense mechanisms are unconscious processes that protect a person from excessive anxiety. They are part of everyday functioning, and mature defenses are associated with positive outcomes. However, the excessive use of defenses or the use of immature defenses is associated with psychopathology. The present study aims to analyze the defense mechanisms that characterize two types of heavy study investment: Studyholism and Study Engagement. We performed a path analysis, MANOVAs, and binary logistic regressions on 422 Italian college students (Mage = 22.56 ± 2.87; 63.5% females). Among the main findings, the strongest (and positive) predictor of Studyholism is regression (maladaptive defense), while for Study Engagement, it is task-orientation (adaptive defense). Hence, Studyholism might be defined as a new potential clinical condition. Additionally, a critical analysis of all the defense mechanisms predicting Studyholism supports the appropriateness of the OCD-related framework for conceptualizing Studyholism. Regarding Study Engagement, even if generally associated with a positive defense style, the finding that it is positively predicted by projection confirms previous studies suggesting that, for some students, it might constitute a coping strategy with paranoid symptoms (and social anxiety and anxiety). Hence, we recommend screening engaged students for social impairment and clinically relevant symptoms that might be hidden by hard studying.
Assessment of Real-Time Active Noise Control Devices in Dental Treatment Conditions
Authors: Kim Ik-Hwan , Cho Hyeonmin , Song Je Seon , Park Wonse , Shin Yooseok , Lee Ko Eun
Published: August 2022

Dental clinics are exposed to various uncomfortable noises. The aim of this study was to quantify the effectiveness of active noise control devices in dental treatment conditions. Two types of commercial headsets (Airpods Pro, QC30) and two types of dental headsets (Alltalk, Quieton Dental) were used for the experiment. Three sounds (high-speed handpiece, low-speed handpiece, and suction system) were measured at three different distances from the dental teeth model, typodont. The distances of 10, 40, and 70 cm reflected the positions of the patient, assistant, and practitioner’s ears, respectively. Sound analysis was performed, and the significance of differences in the maximum noise level using each device was determined with the Kruskal–Wallis test. Dental noise was characterized by the peak in sound pressure level (SPL) at 4–5 kHz and >15 kHz frequencies. The commercial headsets efficiently blocked 1 kHz and 10 kHz of noise. The dental headsets efficiently reduced 4–6 and >15 kHz noise. Quieton had the highest maximum SPL in all situations and positions among the four devices. For a better dental clinic, however, active noise control devices more suitable for the characteristics of dental noise should be developed.
Exploring the Associated Factors of Depression, Anxiety, and Stress among Healthcare Shift Workers during the COVID-19 Pandemic
Authors: Juliana Norsham , Mohd Azmi Nor Amira Syahira , Effendy Nadia , Mohd Fahmi Teng Nur Islami , Azmani Sahar , Baharom Nizam , Mohamad Yusuff Aza Sherin , Abu Izuddin Fahmy
Published: August 2022

Background: The recent pandemic of COVID-19 has had a tremendous impact on healthcare frontliners. This study sought to assess healthcare shift workers’ depression, anxiety, and stress and its associated factors. Methods: The sampling frame includes healthcare shift workers directly managing COVID-19 cases around Klang Valley, Malaysia. The participants’ mental health status was assessed using the Depression, Anxiety, Stress Scale-21 (DASS-21). The associated factors specified in this study include sleep quality, physical activities, and eating habits. Pearson’s χ2 and simple and multivariable binary logistic regression models were constructed following the Hosmer–Lemeshow approach to determine the potential associated factors. Results: A total of 413 participants were recruited. Overall, 40.7% of participants had one or more symptoms of depression, anxiety, or stress. Poor sleep quality was significantly associated with all mental health outcomes of depression, anxiety, and stress. Inactivity was found to be strongly associated with symptoms of depression and anxiety. At the same time, eating habits were strongly associated with anxiety and stress. Conclusions: Sleep quality, inactivity, and eating habits that were found to be associated with the mental health status of healthcare shift workers are modifiable factors that must be addressed to curb mental health issues among this group of workers.
Time Spent on Daily Activities and Its Association with Life Satisfaction among Czech Adolescents from 1992 to 2019
Authors: Kvasková Lucia , Rečka Karel , Ježek Stanislav , Macek Petr
Published: August 2022

Life satisfaction, an important precursor of adolescents’ well-being, is linked to daily activities. Substantial changes have been noted in adolescents’ daily activities over the years, raising the question of possible consequences for life satisfaction. This study aimed to explore changes in adolescents’ life satisfaction and their time spent on daily activities (sleeping, engaging in sports, online gaming, school commuting, time spent at school) and further investigate the associations between adolescents’ life satisfaction and these daily activities. The sample comprised 2715 adolescents from birth cohorts surveyed at four time points between 1992 and 2019. Participants were administered the Daily Activities Inventory and the Berne Questionnaire on Adolescents’ Well-Being. Robust ANOVA with post hoc tests and spline regression were employed. We found cohort differences in sleep duration (8.6 h a day on average in 1992 and 7.5 in 2019). Sleep duration of 8 h and 1 h of sports activities had a beneficial effect on life satisfaction, while more than 1 h of online gaming had a negative impact. Neither school attendance nor commuting to school was associated with adolescents’ life satisfaction. The results of this study can inform public-health policies to promote sleeping and sports habits in adolescence.
Prenatal Environmental Exposure to Persistent Organic Pollutants and Reproductive Hormone Profile and Pubertal Development in Dutch Adolescents
Authors: Berghuis Sietske A. , Bos Arend F. , Groen Henk , de Jong Wilhelmina H. A. , Muller Kobold Anneke C. , Wagenmakers-Huizinga Lucie , Sauer Pieter J. J. , Bocca Gianni
Published: August 2022

Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), may interfere with hormonal processes. Knowledge about the effects of prenatal exposure to PCBs and their hydroxylated metabolites (OH-PCBs) on pubertal development is limited. Therefore, the aim of the current study was to determine whether prenatal environmental PCB and OH-PCB exposure are associated with reproductive hormone levels and pubertal characteristics in 13- to 15-year-old children. In this Dutch observational cohort study, 194 mother–infant pairs were included (1998–2002). Maternal pregnancy serum levels of PCBs, OH-PCBs, and other POPs were measured. At follow-up (2014–2016), we measured serum or plasma levels of reproductive hormones in their children. We assessed Tanner stages and testicular volume (by clinician or standardized self-assessment), and participants completed questionnaires on pubertal onset. In total, 101 adolescents (14.4 ± 0.8 years; 53.7% of invited) participated, and 55 were boys. In boys, higher prenatal PCB levels were associated with higher testosterone levels, higher pubic hair stage, larger testicular volume, and younger age at onset of growth spurt and voice break. In girls, higher prenatal PCB levels were associated with higher stages for breast development. In conclusion, higher prenatal PCB exposure could be associated with more advanced pubertal development in 13- to 15-year-old children.
The Impact of Low-Carbon City (LCC) on Elderly People’s Health: Evidence from a Natural Experiment in China
Authors: Mu Shaohong , Li Weixiu , Mohiuddin Muhammad
Published: August 2022

Rapid urbanization has increased haze pollution, affecting the health of elderly people. This study uses low-carbon city (LCC) data and examines the effects of LCCs on improving the health of elderly residents. Our main purpose is to explore the following question: Can the new urbanization model presented by the LCC alleviate haze pollution and enhance the health of middle-aged and elderly people? This study uses data from the China Health and Retirement Longitudinal Study (CHARLS) and the 2012 LCC pilot to explore whether the LCC can alleviate haze pollution and improve elderly people’s health. The study found that the building of LCCs can reduce blood pressure, improve vital capacity, decrease obesity, and improve memory levels, including short-term and long-term memory. The building of LCCs also reduces the probability of being exposed to haze pollution by increasing the city’s green total factor productivity and the use of green technologies. The study concludes that elderly people received health dividends as a result of the enhancement of living conditions, transportation, and medical support in the LCCs.
Effectiveness of Physical-Activity-Based Interventions Targeting Overweight and Obesity among University Students—A Systematic Review
Authors: Pfisterer Julia , Rausch Constantin , Wohlfarth Doreen , Bachert Philip , Jekauc Darko , Wunsch Kathrin
Published: August 2022

Overweight and obesity, including their prevalence and consequences, reflect a leading public health problem. Studies have already shown that physical activity leads to a reduction in body weight in children and adults. However, the university setting has rarely been investigated. The aim of this review is, therefore, to examine and summarize the effectiveness of physical-activity-based interventions to reduce obesity and overweight in university students. Three databases (PubMed, Scopus, and Web of Science) were searched for relevant studies published in English between January 2010 and February 2022. Quantitative studies conducting a physical-activity-based intervention with overweight or obese university students and reporting changes in BMI were included. Data were described in a narrative synthesis. Out of 16 included studies, 11 reported a significant reduction in BMI. However, all studies except one were able to demonstrate some BMI improvements, whereas all studies reported significant changes in at least one health-related indicator. Aerobic exercises were able to demonstrate the greatest reductions in BMI. This review is the first systematic presentation on the effectiveness of physical-activity-based interventions in overweight and obese university students. Future work should reconsider BMI as the primary outcome if appropriate within the respective study design (i.e., to measure long-term effects). More interventions are needed to improve strategies.
Integrating Cognitive Dysfunction Accommodation Strategies into an HIV Prevention Session: A 2-Arm Pilot Feasibility Study
Authors: Mistler Colleen , Copenhaver Michael
Published: August 2022

Cognitive dysfunction is prevalent among persons on medication for opioid use disorder (MOUD). This cognitive dysfunction has been shown to reduce HIV treatment engagement and medication adherence. We investigated the impact of integrating specific behavioral strategies into an HIV prevention session to accommodate cognitive dysfunction among people on MOUD. Patients on MOUD (n = 20) were randomized to one of two different HIV prevention conditions. The same HIV risk reduction content was presented to both conditions; however, the experimental condition had accommodation strategies integrated into the session. Participants completed a skills checklist at pre-, post-, and 2-week follow-up to examine the level of HIV risk reduction content learned and utilized over time. Participants in the experimental condition indicated high acceptability (95%) for the accommodation strategies. These participants also demonstrated greater improvement in the ability to properly clean a syringe, from pre- to post- (p < 0.02) and from pre- to follow-up (p < 0.02) when compared to participants in the standard condition. Results from this pilot study indicate that accommodation strategies improved participants’ ability to learn, retain, and utilize risk reduction skills over time. This foundation of research indicates a promising, innovative strategy to increase the ability for persons on MOUD to engage in HIV prevention behaviors.
Effects of Market Incentives and Livelihood Dependence on Farmers’ Multi-Stage Pesticide Application Behavior—A Case Study of Four Provinces in China
Authors: Ding Xiuling , Sarkar Apurbo , Li Lipeng , Li Hua , Lu Qian
Published: August 2022

Improvement in pesticide application and efficiency structure has long been recognized as having great significance in reducing pollution, ensuring food safety, and promoting green agricultural development. Based on theoretical analysis, using the survey data of 766 farmers in key tea areas in Shaanxi, Sichuan, Zhejiang, and Anhui provinces in China, the study empirically analyzes the influence of market incentives and livelihood dependence on farmers’ multi-stage pesticide application behavior. More specifically, the study employed ordered probit analysis to craft its findings. The dependent variable of this study is the multi-stage pesticide application problem of farmers, and the core independent variables are market incentives and livelihood dependence, and the judgment is based on the core variable coefficients of the econometric model of farmers at each stage. The study found the following: (i) Market incentives significantly prompted some farmers to give up synthetic pesticide application and farmers tend to choose green pesticides in the type of pesticide application. (ii) Livelihood dependence meant that the proportion of tea income significantly prompts farmers to apply pesticides, and also creates a tendency for farmers to choose green and low-toxic pesticides in the type of pesticide application. The planting period tends to have a moderate impact on applying green and low-toxic pesticides. (iii) The interaction term of market incentives and the proportion of tea income has no significant impact on farmers’ multi-stage pesticide application behavior. The interaction term of market incentives and planting years has impacted negatively on whether farmers apply pesticides, and has no significant impact on farmers’ choice of pesticide application types, but makes farmers increase the amount of green and low-toxic pesticides. (iv) The education level of the household head significantly promotes farmers to choose green and low-toxic pesticides. Seemingly, the brand effect of pesticides significantly encourages farmers to choose green and low-toxic pesticides. In external support, technical training significantly encourages farmers to choose green and low-toxic pesticides. Furthermore, better infrastructure and local market conditions significantly encourage farmers to reduce the use of conventional pesticides.
Analysis of the Elderly’s Preferences for Choosing Medical Service Facilities from the Perspective of Accessibility: A Case Study of Tertiary General Hospitals in Hefei, China
Authors: Li Zao , Gao Yanyan , Yu Li , Choguill Charles L. , Cui Weiyi
Published: August 2022

The accessibility of medical service facilities is a vital influence on elderly people choosing medical treatment. Encouraging residents to seek nearby medical treatment can facilitate the rational layout and diversion of urban medical facilities and reduce health resource waste. However, due to accessibility factors, elderly people may not choose the nearest hospital. In order to investigate such factors, we conducted a questionnaire survey among the elderly from 10 tertiary general hospitals in Hefei, China. On the basis of the origin-destination (OD) cost matrix analysis and statistical analysis of 830 valid questionnaires, this paper analyzed the elders’ selection rules when choosing medical facilities and the factors considered when making a choice. The study found that although 85% of elderly participants valued a short distance to tertiary hospitals, only 31% of them attended the closest hospitals in reality, which correlated with regularity according to their education level, travel activity status, and place of residence. The elderly highlighted road congestion, convenience of public transport stations, and number of transfers as critical in determining whether they sought nearby medical treatment. According to the results, effective ways to encourage the elderly to attend their nearest hospital, from the perspective of accessibility, include easing road congestion, improving the layout of public transport stations, and optimizing urban public transport routes. In particular, when planning future medical facilities, attention should be paid to the elderly with primary school education or below, who cannot travel independently, and those who live far from the city center.
Effectiveness of Deep Water Running on Improving Cardiorespiratory Fitness, Physical Function and Quality of Life: A Systematic Review
Authors: Kwok Manny M. Y. , So Billy C. L. , Heywood Sophie , Lai Matthew C. Y. , Ng Shamay S. M.
Published: August 2022

Deep Water Running (DWR) is a form of aquatic aerobic exercise simulating the running patterns adopted on dry land. Little is known on the effectiveness of DWR despite gaining popularity. The objective of this study is to systematically review the effects of DWR on cardiorespiratory fitness, physical function, and quality of life in healthy and clinical populations. A systematic search was completed using six databases, including SPORTDiscus, MEDLINE, CINAHL, AMED, Embase, and The Cochrane Library, up to February 2022. Eleven studies evaluating the effectiveness of DWR on cardiorespiratory fitness (CRF), physical function, or quality of life (QoL), compared with no interventions (or standard treatment) or land-based trainings were identified. Data relevant to the review questions were extracted by two independent reviewers when means and standard deviations were reported, and standardized mean differences were calculated. A quality assessment was conducted using selected items from the Downs and Black checklist. A total of 11 clinical trials (7 randomized controlled trials) with a total of 287 participants were included. Meta-analyses were not completed due to the high level of clinical and statistical heterogeneity between studies. Compared with land-based training, DWR showed similar effects on CRF with limited studies reporting outcomes of physical function and QoL compared with the no-exercise control group. DWR appears to be comparable to land-based training for improving CRF. The aquatic environment may provide some advantages for off-loaded exercise at high intensity in populations that are weak, injured or in pain, but more studies are required.
Built Environment Features and Cardiometabolic Mortality and Morbidity in Remote Indigenous Communities in the Northern Territory, Australia
Authors: Chakraborty Amal , Cargo Margaret , Oguoma Victor Maduabuchi , Coffee Neil T. , Chong Alwin , Daniel Mark
Published: August 2022

Indigenous Australians experience poorer health than non-Indigenous Australians, with cardiometabolic diseases (CMD) being the leading causes of morbidity and mortality. Built environmental (BE) features are known to shape cardiometabolic health in urban contexts, yet little research has assessed such relationships for remote-dwelling Indigenous Australians. This study assessed associations between BE features and CMD-related morbidity and mortality in a large sample of remote Indigenous Australian communities in the Northern Territory (NT). CMD-related morbidity and mortality data were extracted from NT government health databases for 120 remote Indigenous Australian communities for the period 1 January 2010 to 31 December 2015. BE features were extracted from Serviced Land Availability Programme (SLAP) maps. Associations were estimated using negative binomial regression analysis. Univariable analysis revealed protective effects on all-cause mortality for the BE features of Education, Health, Disused Buildings, and Oval, and on CMD-related emergency department admissions for the BE feature Accommodation. Incidence rate ratios (IRR’s) were greater, however, for the BE features Infrastructure Transport and Infrastructure Shelter. Geographic Isolation was associated with elevated mortality-related IRR’s. Multivariable regression did not yield consistent associations between BE features and CMD outcomes, other than negative relationships for Indigenous Location-level median age and Geographic Isolation. This study indicates that relationships between BE features and health outcomes in urban populations do not extend to remote Indigenous Australian communities. This may reflect an overwhelming impact of broader social inequity, limited correspondence of BE measures with remote-dwelling Indigenous contexts, or a ‘tipping point’ of collective BE influences affecting health more than singular BE features.
The Association of Per- and Polyfluoroalkyl Substances Serum Levels and Allostatic Load by Country of Birth and the Length of Time in the United States
Authors: Bashir Tahir , Asiseh Fafanyo , Jefferson-Moore Kenrett , Obeng-Gyasi Emmanuel
Published: August 2022

Objectives: The aim of this study was to examine the association of per- and polyfluoroalkyl (PFAS) concentrations and allostatic load (AL) by the county of birth and the length of time in the United States of America (U.S.), in a representative sample of U.S. adults. Methods: Data from the 2007–2014 National Health and Nutrition Examination Survey (NHANES) were used in this cross-sectional study on the U.S. adults aged 20 and older. The analysis was stratified by the length of time in the U.S. and by the county of birth. In all, the sample contained those who were US-born (n = 10,264), Mexico-born (n = 4018), other Spanish speaking country-born (n = 2989), and other not–Hispanic speaking country-born (n = 3911). Poisson models were used to assess the differences in AL and PFAS levels depending on country of birth and length of time in the U.S. Results: Estimates indicated that those born in Other non–Spanish speaking counties had the highest PFAS levels among the country of birth category in the database. Regarding length of time in the U.S., those born in Mexico had low PFAS levels when their length of time in the U.S. was short. The Mexico-born category presented the most at-risk high serum PFAS levels, with AL levels increasing by length of time in the U.S. (p-value < 0.001). Conclusion: This study found that PFAS concentrations increased by the length of time residing in the U.S. Those born in other non–Hispanic counties had the highest PFAS levels among all the categories. In general, AL and PFAS levels are mostly associated with the length of time in the U.S., with foreign-born individuals having increased levels of both the longer they stay.