bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Soil Foundation by Integration of Geophysical and Geotechnical Methods at West Kom Umbo Area, Aswan, Egypt
Authors:   Department of Geology, Faculty of Science, Al-Azhar University, Cairo, Egypt, THA Hafeez , M Bekhet ,   Department of Geology, Faculty of Science, Al-Azhar University, Cairo, Egypt, MA Bakr ,   Department of Geology, Faculty of Science, Al-Azhar University, Cairo, Egypt, A Hamdy ,   Senior Engineering Geophysicist, Misr Consult Groub, Cairo, Egypt
Published: June 2021

This research includes combining a geophysical study with a geotechnical study to explore different soil types in the western Kom Umbo area. First: The geophysical study, which includes Electrical Resistivity and Ground Penetrating Radar were conducted to determine the subsurface layers, and to identify “gaps and soil heterogeneity, if any.” Fifty Vertical Electrical Soundings (VESs) were made to determine the layers and the electrical resistivity of the layers. Twelve Ground Penetrating Radar profiles (GPR) have also been created to identify soil homogeneity, gaps, geotechnical properties and to identify “existing cracks or faults. Second: the geotechnical study, which includes the study of a different boreholes in all areas of the study to determine the different layers and geotechnical properties. And field tests (standard penetration test) were done and laboratory tests (such as sieves analysis). And how to determine the degree of soil quality and the ability to build on it. From the above, we can combine the results of geophysics with the results of the geotechnical study to evaluate of soil foundation and to obtain confirmed and accurate information about the nature of the soil in the study area and its homogeneity and determine the possibility of exploiting and benefiting from it in industrial facilities, large, small, residential buildings, green spaces. According to this research the study area is generally divided into two layers, the first layer consists of gravel sand which has a resistivity range from 4189 to 38033 and the second layer is sand which has a resistivity value ranging from 1224 to 9682 ohm/m. and in the present study we have achieved the next procedure on the processed GPR data, displaying 2D profiles that contain the expected anomalies. Because the study area is saturated with silty sand and gravel, part of radar waves is attenuated and the reflections from the subsurface materials are weak. Results with the 100 MHz antennae are the resistive sand, gravel is a very good GPR target, and horizontal layering and stratification are evident throughout the deposit. Engineering studies on samples which collected from different sites in the study area reveal that, the results of uniformity coefficient (Cu) ranging between 3.15 (Very uniform) to 35.56 (Non-uniform). The results of coefficient of gradation range between 0.61 (poorly graded) to 2.41 (Well graded).
Attenuating Effect of Vitamin E and Tinospora cordifolia on Bisphenol-A Induced Apoptosis in Goat Testis
Authors: Sharma R. K.  , Gandhi A
Published: June 2021

During the present study effect of Vitamin E and Tinospora cordifolia on BPA induced goat (Capra hircus) testicular tissue was evaluated. Testicular tissue was exposed to varied concentrations of BPA, Vitamin E and Tinospora cordifolia in three experimental groups along with their specific control for 4 and 8hrs. In group I, the cultured tissue was exposed to three doses of Bisphenol-A viz. 0.01, 1.0 and 100 nM/ml. In group II, Vitamin E (0.1µM/ml) was supplemented along with BPA (0.01, 1.0, 100 nM/ml) and in group III Tinospora cordifolia extract (250 µg/ml) was added with BPA (0.01, 1.0, 100 nM/ml) in the culture media. With the increase in dose level as well as the exposure duration, the frequency of apoptotic cells increased significantly (p< 0.05), as revealed by acridine orange and methylene blue staining. BPA exposure also induced a decline in the antioxidant enzyme activity such as catalase, glutathione peroxidase and reduced glutathione. Vitamin E and Tinospora cordifolia resulted in a decrease in the percentage of apoptotic cells and an increase in levels of catalase, glutathione peroxidase and reduced glutathione activity was observed. Hence, it is concluded that BPA induced more damage at its higher concentration and the antioxidant Vitamin E and Tinospora cordifolia ameliorate the oxidative stress-induced changes, thereby suggesting the  potential of Vitamin E and Tinospora cordifolia in counteracting the cellular damage induced by agents like BPA.
Da história das ideias à história social das ideias
Authors: Mesquita Gustavo Rodrigues
Published: June 2021

O artigo examina o processo de renovação epistemológica da história das ideias considerada como abordagem especializada nos problemas ontológicos e epistêmicos das ideias-unidade, sucedido na França e na Alemanha durante a eclosão do movimento dos Annales a partir dos anos 1930, concomitantemente à insurgência de uma nova abordagem metodológica adaptada ao domínio das ciências sociais, e que foi designada por seu fundador, Karl Mannheim, de sociologia do conhecimento. Pode-se inferir que ambas as abordagens ”“ que eram contemporâneas entre si ”“, embora conservassem algumas particularidades quanto ao método de análise e de explicação, resultaram de um duradouro movimento de crítica epistemológica cujo escopo incidiu, sobretudo, na tradicional história das ideias praticada à maneira de Arthur Lovejoy. Ocorre, portanto, uma mudança na base heurística da metodologia de investigação histórica: da teoria ontológica das ideias à teoria sociológica das ideologias, não mais perscrutando o conhecimento filosófico produzido por pensadores isolados, mas as funções que o pensamento desempenha nos rumos da sociedade.
Contra o ‘inimigo interno’ a favor do Governo Militar
Authors: Silva Camila Gonçalves
Published: June 2021

Este artigo é parte do resultado final da dissertação de mestrado intitulada: “A censura veste farda: elites conservadoras, policiais militares e o consentimento da imprensa escrita a censura, durante o Governo Militar em Montes Claros de 1964-1985”, cuja defesa realizou-se em janeiro de 2011. A pesquisa esteve vinculada ao Programa de Pós-Graduação em História da Universidade Federal de Juiz de Fora/PPGH-UFJF. A discussão, ora apresentada, se concentra, num primeiro momento, na compreensão do perfil da imprensa escrita de Montes Claros, que atuou durante o Governo Militar Brasileiro nos impressos: Diário de Montes Claros e Jornal de Montes Claros. Posteriormente, analisaremos a inserção de censores nas redações dos referidos impressos por parte do 10º Batalhão de Polícia Militar de Montes Claros. Com base na metodologia da História Oral, coletamos entrevistas com vários jornalistas que atuaram nos referidos impressos. Estas foram fontes fundamentais para a realização deste estudo.
How Does Modification Affect the Processing of Formulaic Language? Evidence from L1 and L2 Speakers of Chinese
Authors:   , Jiang Shang
Published: June 2021

It has been well documented that formulaic language (FL) – strings of language above the word level in most cases, such as binomials, collocations, n-grams, idioms – enjoys a processing advantage over novel language (e.g., Arnon & Snider, 2010; Carrol & Conklin, 2020; Hallin & Van Lancker Sidtis, 2017; Siyanova-Chanturia, Conklin, & Schmitt, 2011a; Siyanova-Chanturia, Conklin, & van Heuven, 2011b; Tremblay, Derwing, Libben, & Westbury, 2011). The majority of these studies focused on formulaic sequences (FSs) in their original form. In natural language use, however, many FSs are modified with words intervening in-between the individual constituents (e.g., provide information → provide some of the information, see Vilkaitė, 2016a). Whether or not the processing advantage can be extended to modified FSs remains poorly investigated. In this thesis, three reading studies were conducted to address this gap from the perspective of Chinese FL processing, in which the influence of phrase frequency, modification degree, age, and L2 proficiency, were explored and discussed in detail.

Study 1 recorded the eye movements of L1 Chinese adults when reading sentences embedded with frequent collocations and infrequent controls. The results suggested a significant processing advantage for collocations over relative controls. Critically, the processing advantage for collocations in their original form extended to their short- (with two Chinese characters inserted in the middle of the phrase) and long-insertion forms (with four Chinese characters inserted in the middle of the phrase). The processing advantage was largely observed in the whole phrase in the late processing stage.

Study 2 and Study 3 borrowed the materials from Study 1 and applied them in a self-paced reading experiment with L2 Chinese learners from Japan and Thailand of different language proficiencies, and L1 Chinese children at Grades Three and Six, respectively. The results of Study 2 revealed a significant processing advantage for collocations over respective controls in L2 learners. More crucially, the processing advantage for L2 collocations persisted in their short- and long-insertion forms. L2 proficiency and L1 background were also found to play a role in L2 FS processing.

The results of Study 3 suggested a significant processing advantage for collocations over respective controls in L1 children. More importantly, the processing advantage for collocations remained in their short- and long-insertion forms in sixth graders; and remained in their short-insertion form in third graders. Furthermore, age was found to play a role in FS processing in children.

Contributions to the current literature and methodologies are discussed at the end of the thesis.
The Petrology and Geochemistry of a Suite of Intrusive Igneous Rocks from the Southern Kermadec Arc-Havre Trough, SW Pacific
Authors:   , Tozer Brenton
Published: June 2021

The study of intrusive igneous rocks can provide insights into deep crustal processes. In active intraoceanic arc environments, the opportunity to study of these intrusive igneous rocks usually comes from xenoliths entrained within eruptive products, as accessibility to in situ intrusive rocks is limited. This thesis documents a suite of the first intrusive samples dredged from the Havre Trough, which provide insights into deep magmatic processes in this intraoceanic back-arc system. The suite of ten intrusive igneous rocks were dredged from Basin E, a back-arc basin (BAB) in the Kermadec Arc-Havre Trough (KAHT) and consist of in situ gabbroic meso- to orthocumulates. Four representative samples were selected from the suite of ten on the basis of grainsize, and from them a petrogenetic model was built to determine the associations of the samples within the magmatic system of the region. The four samples all exhibit comparable mineral assemblages of plagioclase, clinopyroxene, and magnetite, with olivine and orthopyroxene absent. Texturally the samples appear to have formed in (a) magma chamber(s) where the minerals cooled slowly and formed relatively large, euhedral crystals that trapped interstitial melt between them. The interstitial melts crystallised forming more evolved intercumulus material (plagioclase + quartz ± amphibole ± apatite). Three of the four samples have coarser grainsizes (1-2 mm), and exhibit similar magnetite temperature estimates, indicating that they formed from similar melts. The other sample has a finer grainsize (<1 mm), and exhibits lower temperature estimates, indicating that this sample formed from a lower temperature, faster cooling melt. Plagioclase compositions follow a similar trend to plagioclase phenocrysts from modern back-arc volcanoes which indicates that these samples have an association with the modern magmatic system rather than the now extinct Miocene (Colville) Arc. Clinopyroxene trace element data are also consistent with these samples being associated with the modern subduction system. The magma chamber(s) that the samples formed in, comes from a mid-lower crustal depth, 3-6 km based on pressure estimates from amphibole crystal chemistry. The exposure of rocks from this depth would have been facilitated by normal faulting associated with rifting and opening of the Havre Trough. Petrologic and geochemical analyses of these cumulates suggest that the deep, back-arc basins consist of entirely new magmatic material formed from BAB volcanism, with no evidence for pre-existing crust.
Ensuring Māori student success and inclusion of te aō Māori through initial teacher education
Authors: McRae Hiria , Averill Robin
Published: June 2021

Teacher commitment to Te Tiriti o Waitangi is emphasised within the latest Code of Professional Responsibility and Standards for the Teaching Profession (Education Council, 2017). Teachers must explicitly demonstrate commitment to tangata whenuatanga and Te Tiriti o Waitangi. This mandate is encouraging for Māori education needs and aspirations. We describe the use of a culturally sustaining teacher practice framework to examine Māori education policy implementation implications within an initial teacher education te ao Māori course. We explain how course content, delivery and assessment aspects can be critiqued and policy implications identified to illustrate the usefulness of the framework for teacher educators and practising teachers. We demonstrate how the framework can be a useful tool for teacher educators to examine culturally sustaining practice in preparing themselves and student teachers to work effectively with indigenous learners.
‘I Can Lead the Life That I Want to Lead’: Social Harm, Human Needs and the Decriminalisation of Sex Work in Aotearoa/New Zealand
Authors: Armstrong Lynzi
Published: June 2021

Background: Sex work is commonly understood to be a risky occupation. Sex work law debates coalesce around the issue of harm, with differing perspectives regarding what constitutes harm, how harm is produced and what needs to change to mitigate it. While sex work is often portrayed as inherently harmful, sex workers and researchers have challenged this assumption, calling attention to the relationship between harm and policies in place. Criminalisation, in its many and varied forms, is thought to exacerbate harms that can occur in sex work, while decriminalisation is understood as creating conditions conducive to minimising harm. However, the decriminalisation of sex work remains rare, and more research which examines how decriminalisation works in relation to harms is critical. This paper uses the concept of social harm to unpack the implications of sex work policies and examine the experiences of sex workers in New Zealand, where sex work is decriminalised. Methods: Semi-structured in-depth interviews were conducted with 46 sex workers in New Zealand in 2018 and 2020 across two studies focused on examining experiences and perceptions of stigma and discrimination in this context. The interviews were thematically analysed using NVivo data analysis software. Results: The experiences of participants demonstrate how involvement in sex work had improved their lives in multiple ways. Participants described the importance of sex work in improving their quality of life by ensuring that they could better meet their everyday needs, the autonomy this afforded them and how decriminalisation helped to enable this. The validating impact of decriminalisation in acknowledging sex workers as people with rights is also evident in participant’s experiences. Conclusions: Social harm is a framework that can help illuminate socio-economic harms which influence pathways into sex work for some people and the compounding harms of criminalising regimes. The benefits of engaging in sex work are often overlooked in policy debates. Although sex work is not easy work, engaging in sex work can have positive impacts on the lives of people who pursue it. Full decriminalisation of sex work is the only responsible option for societies seeking to reduce harm.
Redefining Supports: Extending Mass Customization with Digital Tools for Collaborative Residential Design
Authors: Lo Tian Tian , Mohamed Basem , Schnabel Marc Aurel
Published: June 2021

No description supplied
REIMAGINING RELATIVITY Transitioning the physical body into a virtual inhabitant
Authors: Rogers J , Schnabel Marc Aurel , Moleta Tane
Published: June 2021

This paper explores the ideas and mechanics through a case study which generated a reimagined means of inhabiting a speculative immersive environment. Currently, many users reside within virtual environments for their own leisure, work, or any other reason desired from short amounts of time to extreme lengths. This paper shows the generation directly relative to the inhabitant, where gravity, orientation, scale, and locomotion is completely dynamic. Details within this paper experiment with the laws and bounds of the virtual space within a real-time game engine where reimagining the way one inhabits space compared to current norms of real-world inhabitation is possible with creativity and applied knowledge. Escher’s lithograph of Relativity is the driving concept explored within this paper beginning with creating gravitational pulls in multiple directions within the immersive virtual reality environment to accommodate various sources of gravity. The result of the case study demonstrated the generation of new virtual relativity laws reimagining how the virtual space is inhabited, in short, omnidirectional flying, gravitation defined by the inhabitant to geometry relationship, controlled local scaling, and populating space with multiple inhabitants in a unique manner.
Beyond the portal
Authors: Qureshi C , Moleta Tane , Schnabel Marc Aurel
Published: June 2021

In its ambitions, the paper aims to propose a proof of concept for a Virtual, Augmented and Mixed (VAM) environment that digitally overlays a multifaith space in order to optimize their use, essentially transforming itself to the spiritual needs of the user. In order to do so, a mixed reality experience was developed by investigating and interpreting both the tangible and intangible rituals of prayer. By incorporating an immersive experience, the project promotes the idea of a multifaith space that moves beyond the notion of an “empty white room (Crompton, 2013, p.487)”. To develop an immersive experience that caters to people of all religions or no religion is beyond the scope of this project. Hence, by creating a VAM environment for users of the Muslim faith the project may be able to support design ideologies for others, furthering research in this field.
Amplifying citizens’ voices in smart cities: An application of social media sentiment analysis in urban sciences
Authors: Sayah I , Schnabel Marc Aurel
Published: June 2021

In the past decade, urban researchers have paid significant attention to the emergence of computer science and urban planning. According to the literature, social media as a pool of real-time citizen feedback can be investigated to inform smart city synergies. However, the success factors of such an approach have not been thoroughly investigated. In this study, various factors were derived from an extensive literature review to create an efficient e-participation platform. It is explained how our proposed platform 1) complies to the data protection regulations 2) uses advanced text analysis and natural language processing (NLP) tools to identify opinions and emotions 3) maintains persistent communication between citizens and city planners 4) incorporates creative visualisation techniques 5) is informative for its target audience 6) takes into consideration the socio-cultural diversity and 7) can be used as an informing tool in combination with offline methods of participation.
Parametric Thinking in Form-Based Code Evaluation
Authors: Zhang Yingyi , Schnabel Marc Aurel
Published: June 2021

The concept of Form-Based Code is of central importance in American New Urbanism. There is an increasing concern on Form-Based Code’s components and adoptions in cities and countries in the USA. This paper aims to extend Form-Based Code’s study to high-density cities of Asia. It explores the methodology of embedding parametric thinking into the multi-scenario evaluation of Form-Based Code. The methodology framework is developed by taking advantage of parametric modelling instruments which visualizes the coding procedure on software interfaces. Using Tsim Sha Tsui, Hong Kong as the experimental site, the paper concludes with a parametric evaluation system towards a walkable and accessible environment in the volumetric urban morphology of high-density cities.
Virtual Instruments for Urban Design Decision-Making Process
Authors: Schnabel Marc Aurel , Chowdhury Shuva
Published: June 2021

No description supplied
Glitch architecture
Authors: Schnabel Marc Aurel , Haslop B
Published: June 2021

Architectural designs are visualised on computer screens through arrays of pixels and vectors. These representations differ from the reality of buildings, which over time will unavoidably age and decay. How, then, do digital designs age over time? Do we interpret glitching as a sudden malfunction or fault in the computation of the design’s underlying data, or as digital decay resulting not from the wear and tear of tangible materials but from the decomposition of the binary code, or from system changes that cannot appropriately interpret the data? By exploring a series of experimental design practices for deployments and understandings that are the consequence of malfunctions during computational processing, glitches are reinterpreted. Advancing from two-dimensional glitch art techniques into three-dimensional interpretations, the research employs a methodology of systematic iterative processes to explore design emergence based on glitches. The study presents digital architectural form existing solely in the digital realm, as an architectural interpretation of computational glitches through both its design process and aesthetic outcome. Thus, this research intends to bring a level of authenticity to the field through three-dimensional interpretations of glitch in an architectural form.
Peculiarities of surgical treatment of patients with gastroesophageal reflux disease
Authors: Matviychuk B. O. , Stasyshyn A. R. , Hurayevskyy A. A.
Published: June 2021

Objective. To analyze the effectiveness of various methods of laparoscopic antireflux operations in patients with gastroesophageal reflux disease.

Materials and methods. The results of treatment of 177 patients with gastroesophageal reflux disease from 2015 to 2021 were analyzed. Patients were divided into three groups: 1st - 62 patients who underwent laparoscopic antireflux surgery of our own modification (Patent of Ukraine No 59772); 2nd - 91 patients who underwent laparoscopic Nissen fundoplication; 3rd - 24 patients who underwent laparoscopic Toupet fundoplication. 

Results. 36 months after surgery in the 1st group the recurrence rate of gastroesophageal disease was 1.6%, recurrence of hernia of the esophageal orifice - 1.6%, in the 2nd group - 7.7 and 3.3%, respectively; in the 3rd group - 12.5 and 8.3%, respectively.

Conclusions. The application of a new integrated approach to the surgical treatment of gastroesophageal reflux disease reduces the number of postoperative complications (gas -bloat syndrome - 3 times, dysphagia - 5 times), the recurrence rate of gastroesophageal reflux disease - 5 times and recurrence of esophageal hernia - 2 times, improves the quality of life of patients 36 months after surgery in 2.6 times and increases the timeliness of diagnosis and facilitates the choice of differentiated treatment tactics.
Zbrodnia pomorska 1939 r. w powiecie tczewskim: sprawcy, ofiary, pamięć, odpowiedzialność
Authors: Tomkiewicz Monika
Published: June 2021

Zbrodnia pomorska 1939 r. była przede wszystkim eksterminacją dziesiątek tysięcy przedstawicieli polskiej inteligencji, rozstrzelanej w ramach „Inteligenzaktion”, ale także rolników, robotników i rzemieślników, zamordowanych przez niemieckich sąsiadów. Po zajęciu powiatu tczewskiego przez wojska niemieckie od 2 września 1939 r. władze okupacyjne zaczęły tworzyć obozy internowania i punkty zbiorcze w więzieniach dla ludności polskiej. Na terenie powiatu tczewskiego miejsca takie znajdowały się w więzieniach sądowych w Tczewie i Gniewie, Szkole Rzemieślniczej w Tczewie, na terenie Fabryki „Arkona” w Tczewie, na terenie zamku w Gniewie oraz w Seminarium Duchownym w Pelplinie. Stamtąd więźniowie wywożeni byli do miejsc straceń w Lesie Szpęgawskim i w koszarach w Tczewie. Egzekucje poprzez rozstrzelanie na terenie koszar prowadzili członkowie załogi obozu „Internierungslager” i komanda SA w Gdańsku. Rozstrzeliwań dokonywano głównie na terenie dawnej prochowni i na placu ćwiczeń za koszarami. Ciała zamordowanych były grzebane na terenie koszar. Zginęło tam wówczas około 120 osób. W grupie tej byli pracownicy polskiej administracji, przedstawiciele inteligencji, adwokacji, nauczyciele i duchowni (w tym 20 księży kapituły pelplińskiej). W wyniku prac ekshumacyjnych przeprowadzonych w 1945, 1947 i 1976 r. zidentyfikowano zwłoki 79 osób. Obóz tczewski funkcjonował do stycznia 1940 r. i w jego murach osadzono około 500 więźniów.
Wpływ pandemii COVID­­‑19 na pomorski rynek pracy
Authors: Rutkowski Mateusz
Published: June 2021

W artykule podjęto próbę oceny wpływu pandemii COVID­­‑19 na pomorski rynek pracy. Autor analizuje zmiany poszczególnych wskaźników opisujących sytuację na pomorskim rynku pracy oraz omawia trudności, z jakimi w sferze zawodowej w wyniku pandemii borykają się przedstawiciele szczególnych grup na rynku pracy – kobiety i osoby młode. Wnioski wskazują na negatywny wpływ pandemii COVID­­‑19 na regionalny rynek pracy i zatrudnienie, a z negatywnymi konsekwencjami przyjdzie mierzyć się jeszcze długo po ustaniu pandemii.
Finansal Planlama ve İşletmelerin Nakit Kararlarında Finansal Planlama Kullanılması
Authors: EROL Mikail , AYBOĞA Hanifi
Published: June 2021

Finansal planlamalar, bir işletmenin hedeflerine ulaşması için gereken kaynakların belirlenmesine ve bu kaynakların nasıl kullanılacağının gösterilmesine yönelik olarak hazırlanan iş planlarının önemli bir safhasını oluşturmaktadır. Bir işletmenin iş planında yer alan işi üretmek için gerekli olan üretim faktörleri, enerji ve makinelerin hangi kaynaklarla ne zaman elde edileceğini göstermektedir. Bu nedenle iş planı ne kadar doğru hazırlanırsa finansal planlama da aynı oranda başarılı olmaktadır. Finansal planlamanın işletmeler açısından önemi büyüktür çünkü yapılan planlar işletmenin mali kararlarında kullanılmaktadır. Planlama, işletmelerde finans yöneticisinin görevinin önemli bir parçasıdır ve finansal planlama işletmenin finans yöneticileri tarafından işletmenin nakit kararlarının belirlenmesinde kullanılmaktadır. Yaşanan küresel ekonomik krizlerde, düzenleme ve denetim mekanizmalarının iyi olduğu söylenen ülkelerde çıkması ve gelişmiş ekonomileri ciddi biçimde etkilemesi planlama, düzenleme ve denetimde yeni anlayışların ve yeni yapılanmaların gerektiğini göstermektedir.
Marketing automation
Authors:   Belarusian State Economic University, Golik Vadim
Published: June 2021

Рассматриваются сущность автоматизации маркетинговой деятельности, а также преимущества цифровизации, которые заключаются в возможности сокращения затрат на содержание маркетинговой службы, повышения контроля за работой ее сотрудников, улучшения взаимоотношений с клиентами, экономии времени на проведение мероприятий и т. д.
Use Of Anti Hypertension And Factors That Affect The Compliance Of Drinking Anti Hypertension In Hypertension Patients In Cisalak Pasar Depok Health Center
Authors: Bahar Meiskha , Yusmaini Hany , Wahyuningsih Sri
Published: June 2021

Compliance with treatment is an important factor in the health of hypertensive patients. Compliance is a prerequisite for the effectiveness of hypertension therapy, whereas patient non-compliance with antihypertensive drugs is one of the main factors in the failure of therapy. There are several factors that influence medication adherence and some basic principles of therapy that need to be considered to reach the target of therapy and reduce complications of hypertension.

Hypertension sufferers in the Cisalak Pasar Community Health Center are quite numerous, they are generally elementary school and not schooled (74.2%). Kidney complications and a combination of heart and kidney are also quite large, which is 40%. This study aims to determine the pattern of antihypertensive administration and the relationship of age, education level, degree of hypertension, complications and type of therapy with the level of adherence to taking medication for hypertensive patients at the Cisalak Pasar Community Health Center. The research design used in this study was a descriptive cross-sectional. The subjects of the study were essential hypertension patients at the Cisalak Pasar Health Center, Depok who met the inclusion and exclusion criteria. The results of this study are that the pattern of antihypertensive administration is in accordance with JNC 8, there is no relationship between age, education level, hypertension degree and the number of drugs taken with medication compliance, and there is a relationship between the presence or absence of complications with medication compliance
Hubungan Antara Dukungan Keluarga Dan Motivasi Dengan Kualitas Hidup Pada Pasien Yang Menjalani Terapi Hemodialisa di RSI Sultan Agung Semarang
Authors: Rizky Sulymbona Deni , Setyawati Retno , Khasanah Furaida
Published: June 2021

Life quality of chronic kidney disease patients who undergoing hemodialysis therapy is still being an attractive problem for health professionals, a patient will feel worth if they get support from their family and have the motivation to undergo hemodialysis therapy. This research aims to acknowledge family support and motivation with life quality in patients undergoing hemodialysis therapy in Islamic Sultan Agung Hospital Semarang. This research is analytic observational study, using total sampling technique with 87 numbers of respondents. Data collection using a questionnaire. Data Analysis technique using a chi-square test. Chi-square test for family support and life quality discovers result p-value 0,005, meanwhile for motivation and life quality hemodialysis patients p-value 0,0001. Family support and motivation is correlated wit life quality on patients undergoing hemodialysis. The nurse has a big role to give support and motivation toward patients and family.
Limfoma pada anjing Golden Retriever
Authors: Amanda Ayu Syilvita
Published: June 2021

Limfoma adalah kanker pada sistem limfatik. kasus limfoma belum diketahui penyebabnya, namun terdapat beberapa faktor resiko yang dapat memicu terjadinya limfoma. Limfoma sering terjadi pada anjing berusia diatas 1 tahun atau berkisar pada usia 10 tahun. Tulisan ini melaporkan kasus limfoma pada anjing Golden Retriever betina berusia 8 tahun. Diagnosa dilakukan melalui pemeriksaan fisik dan kimia darah, sedangkan pemeriksaan penunjang berupa sitologi dan histopatologi tidak dilakukan dalam kasus ini. Terapi yang digunakan yaitu bedah pengangkatan kanker, lalu pemberian antibiotik dan antiinflamasi untuk pascabedah. Luka bekas jahitan menutup selama kurang lebih 6 minggu. Pemberian antibiotik topikal dan salep ekstrak placenta sangat membantu mempercepat pertumbuhan jaringan kulit.
Tampilan estrus kambing Peranakan Etawa dalam program sinkronisasi menggunakan prostaglandin F2α yang diinjeksikan pada submukosa vulva
Authors: Prastowo Sigit , Yusanti Anna , Nisaa’ Chairul , Sunarto . , Widyastuti Rini
Published: June 2021

Penelitian ini bertujuan membandingkan tampilan estrus kambing Peranakan Etawa (PE) dalam program sinkronisasi estrus menggunakan hormon PGF2α  yang diinjeksikan pada submukosa vulva (SMV). Sebanyak 10 ekor kambing PE berumur 2,5 tahun dan telah mengalami 2 kali partus digunakan sebagai unit percobaan. Injeksi PGF2α secara SMV pada P1 = dosis 0,1578 mg/ml (n=5) dan P2 = dosis 0,0789 mg/ml (n=5) menggunakan dosis ganda dengan interval injeksi 11 hari. Tampilan estrus diamati dan diukur menggunakan Draminski Heat Estrous Detector (DHED) mulai 24 jam setelah injeksi kedua setiap 8 jam hingga tanda estrus menghilang. Nilai hambatan arus listrik (HL) yang ditampilkan oleh DHED selama pengamatan digunakan untuk melihat awal, puncak dan akhir estrus. Hasil pengamatan menunjukkan bahwa nilai HL puncak estrus berbeda dengan awal dan akhir estrus (p<0,05) pada setiap P1 dan P2. Rata-rata nilai HL pada P1 dan P2 masing-masing 480,00±8,16 dan 485,00±12,91. Onset estrus adalah 24 dan 120 jam secara berturut-turut pada P1 dan P2 dan lama estrus adalah 44,00 dan 43,50 jam. Injeksi hormon PGF2α pada kambing PE secara SMW mampu memperlihatkan tampilan estrus dengan onset lebih lama pada dosis hormon yang lebih rendah.
Lobomikosis pada lumba lumba hidung botol Tursiop aduncus
Authors: Indrawati Agustin , Meen Lee Xia
Published: June 2021

Lobomikosis merupakan penyakit yang menyerang bagian kulit yang disebabkan oleh Lacazia loboi (yeast-like organism) dari ordo Onygenales. Tulisan ini melaporkan seekor lumba-lumba hidung botol Indo Pasifik Tursiop aduncus jantan berumur 14 tahun yang mengalami kelainan pada kulit berupa nodul-nodul ulseratif menyerupai ringworm pada sirip ekor. Gejala yang ditimbulkan dengan cepat menyebar dan gejala pada permukaan kulit mengalami penggabungan nodul yang menyerupai bunga dan disertai adanya perdarahan. Pemeriksaan laboratorium ditemukan bentukan sel khamir dan bentuk unisel. Pengobatan dilakukan dengan menggunakan antifungal ketoconazole 200 mg (mycoral®) dan ketoconazole cream 2% selama 30 hari. Pengobatan lain yang digunakan adalah antihistamin Homochlorcyclizine HCl 20 mg (Homoclomin®) dan antibiotika Quinolone 500 mg (Ciproxin®) untuk mengobati infeksi sekunder akibat bakteri. Lumba-lumba hidung botol Indo Pasifik dinyatakan sembuh dengan menghilangnya nodul ulseratif dari sirip ekor setelah 30 hari pengobatan
Gambaran Makroskopis Persembuhan Luka Mukosa Buccal Tikus Putih (Rattus norvegicus) Pascapemberian Policresulen
Authors: Tunggadewi Tri Isyani , Wahyudi Tony , Shofwan Aisyah Alviatus , Khoerunnisa Anggri Azhari , Darusman Huda Salahudin
Published: June 2021

This study aimed to investigate the effect of policresulen treatment with various concentrations on the wound healing in buccal mucosa of white rats (Rattus norvegicus) through macroscopically observation. The number of 54 rats were divided into six treatment groups policresulen with concentration of 36%, 10%, 5%, 1%, 0.3% and one control group. The buccal mucosal injury was made with a 0.5 cm biopsy punch. The treatment of mucosal injury was conducted by dropped policresulen on the 2nd day until the 5th day after the injury. Macroscopic observation under a stereo micro-scope was conducted on the wound diameter, redness, swelling, and necrose. The results showed that wound healing was influenced significantly with concentration of the policresulen. The best healing was shown on lowest concentration marked which has lowest size of the wound diameter (0.50 ± 0.00 cm), the lowest tissue redness (0.00 ± 0.00), lowest final swelling at a concentration of 0.3%. Clinical evaluation of wound tissue necrose parameters which were seen to be most severe at 10% policresulen administration followed by 36% concentration and the least necrose shown on policresulen administration 0.3%. Therefore, based on macroscopic images with parameters of wound diameter, redness, swelling, and necrose suggested that policresulen used for wound healing process are at a concentration of 0.3%.
O PIBID E A FORMAÇÃO DE PROFESSORES: IDENTIDADE E SUBJETIVIDADE
Authors: Melo Eloídes de Sousa , Pereira Carmel do Nascimento , NASCIMENTO GISELE DE ALMEIDA , Vasconcelos Elizandra Rêgo
Published: June 2021

Este trabalho é parte das discussões realizadas no grupo EPENBIO sobre a formação de professores e as
experiências vivenciadas em um programa de iniciação à docência – PIBID evidenciando de que maneir
Atualidade de Alceu Amoroso Lima
Authors: Andrade Djalma Rodrigues de
Published: June 2021

Sejam minhas palavras iniciais de agradecimento ao Centro Alceu Amoroso Lima para a Liberdade. Ao formular-me este convite concede-me dupla satisfação: a primeira, distinguindo-me com a incumbência de discorrer sobre a atualidade da mensagem de seu patrono; e a segunda, juntando-me a quantos nesta instituição buscam no ideário de Alceu, reunidos sob o teto que por longos anos o acolheu aqui na Mosela, inspiração no serviço à causa da pessoa humana e da liberdade...
Penerapan RAD pada Aplikasi E-Learning Lembaga Bimbingan Belajar Gold Generation
Authors: Nurhasan Usman , Mujahid Muhammad , Sukmadewi Ferina
Published: June 2021

The development of information and technology has helped people to do their activity. In future living, information and technology will be the most dominant sector. Technology takes part in most of the aspects such education. Technology’s role is urgently needed, the example is Gold Generation Tutoring Agency as their service quality improvement. During this time tryout and tasks is done in a paper and not recorded on a database. It complicates the agency officers to manage the students’ grade and their tasks. And tutors find themselves in difficult situation in monitoring their students. Another popular name at the moment is E-Learning, it is one of learning process models that utilize media of information and technology communication especially internet. By the existence of e-learning that is directly connected to a database will ease the admin and the officers of the tutoring agency to manage the students grade and correct their task results, and not only for better service, but also for easing the students with lesson materials. According to the things mentioned above, "Web-based E-Learning Application of Gold Generation Tutoring agency" is made. This application is expected to help in managing students grade and correcting their tasks in Gold Generation Agency
Peringatan Otomatis Pada Internet of Things Sistem Deteksi Smart Motion
Authors: Anwar Nizirwan , Tjahjono Budi , Tarigan Masmur , Adhy  Rosian Dewanto , Widiyasono Nur , Hermawan Rudi
Published: June 2021

The main problem in this research is the increase in cases of theft and robbery. This incident was caused by the busyness of everyone in their daily lives, so they forgot about the safety of their house. An Internet of Things (IoT) based home security system that utilizes a PIR sensor as a human motion detector and then sends a notification in the form of a notification via SMS or e-mail is one solution to overcome the problems that have been previously proposed in previous research. However, to further clarify the warning sent from the system, a home security system is needed that can attach an image to the notification. In this study, an IoT-based home security system was developed. The IoT security system being developed can automatically send a warning message by attaching an image when the PIR sensor detects human presence. The IoT system requires a Raspberry Pi as a microcontroller that is connected to the internet, a PIR sensor to detect human movement and a Pi Camera to win an image when there is an encounter with a human within the range of the PIR sensor. Experiments in this study show that the IoT system can automatically send warning messages via the Telegram application by attaching an image when the PIR sensor detects human presence in various light conditions with a distance of 0-5 meters and the speed of sending email alerts is influenced by the condition of the internet network connection and file size. images sent.
Promising Diagnostic Markers of Colon Cancer
Authors: Volkov S. V. , Lobanov S. L.
Published: June 2021

Background. The incidence of colon cancer over the past decade has been growing markedly in the Russian Federation, with about 50 % cases detected at stagesIII–IV of the disease, when a clear clinical picture of the disease appears. In this regard, the search for new methods for early diagnosis of RTK is undoubtedly relevant.

Objective. To determine the standard composition of the aerobic parietal colon microbiota and the level of cytokines (chemokines and growth factors) in patients with cancer of the left half of the colon and to assess the possibility of using these data in the diagnosis of the tumor process.

Materials and methods. Blood tests were performed on the day of the study using two test systems (BioLegend): multiplex kit for determining growth factors, chemokine multiplex kit. The composition of the intestinal microbiota was determined in colon biopsy specimens by the bacteriological method using the standard test systems StaphyTest, StreptoTest, and EnteroTest.

Results. There is an increase in the number of Clostridiumspp. and a decrease in Bifidobacteriumspp., E. coli in the colon during the transformation of a healthy person’s mucosa into a malignant tumor (p < 0.05); a clear tendency was revealed for both an increase (EGF, HGF, M-CSF, PDGF-AA, PDGF-BB, IP-10) and a decrease (MCP-1, RANTES) of the level of chemokines and growth factors under colon cancer conditions. In addition to general quantitative changes in the intestinal microbiota, the level of the investigated substances, a statistically significant dependence was established on the sex, age of the patient, as well as the degree of differentiation and form of tumor growth.

Conclusion. It was established that changes in the quantitative composition of the intestinal microbiota, the level of some biologically active substances that occur precisely in the conditions of colon cancer, can be interconnected and interdependent, and also serve as an additional diagnostic marker in the detection of a malignant tumor.
Biomarkers of Myopic Choroidal Neovascularization in Women, Determining the Clinical Course and Response to Anti-VEGF Therapy
Authors: Grigorieva A. V. , Iureva T. N. , Kursakova Ju. V. , Ivanova E. I. , Samsonov D. Yu. , Mikhalevich I. M.
Published: June 2021

Aim: to identify clinical and laboratory biomarkers that determine the nature of the course of myopic choroidal neovascularization (mCNV) and the response to anti-VEGF therapy in women.

Material and methods. A prospective non-randomized study was conducted in 52 patients (52 eyes) with active mCNV, treated with ranibizumab intravitreally, 0.5mg. After 12months, the suppression of CNV activity, the number of injections and the fellow eye inclusion in the pathological process were taken into account. There were 2 groups: with a favorable clinical course (n = 31, age – 33,0 ± 5,1 years, anterior-posterior axis (APA) 28,5 ± 0,3 mm) and an unfavorable clinical course (n = 21, age – 34,0 ± 4,1 years, APA – 29,01 ± 0,1 mm). Structural retinal changes, choroid thickness, retinal blood flow, and heart rate were evaluated using OCT and OCTA protocols (Optovue XR Avanti, USA). Studies were conducted before the start of therapy and then one time per month. The concentration of sex and pituitary hormones (ELISA analyzer “Immunohem-2100”), lipoprotein A, Apo B/Apo A (Accent 200 Cormay, Poland), coagulogram data (Helena C-2, UK), and the concentration of highly sensitive C-reactive protein in blood serum before the start of antiangiogenic therapy were studied once.

Results. In the first group, 1.4 ± 0.7 ranibizumab injections were administered to suppress the CNV activity. In the opposite group – 3.5 ± 2.1 injections, in 73.7 % of cases, relapses were diagnosed, in 3 cases – primary CNV in the fellow eye. Clinical and laboratory biomarkers of the unfavorable clinical course of mCNV were identified: extreme choroidal thinning, highly organized membranes of a large area, dome-shaped deformation of the posterior pole, excess of the reference values of lipoprotein A, fibrinogen and highly sensitive C-reactive protein by two or more times, an imbalance of sex and pituitary hormones (excess of the reference values of prolactin, follicle stimulating hormone, cortisol, progesterone concentration decrease), a predominant change in the menstrual-ovarian cycle according to the type of amenorrhea and opsomenorrhea.

Conclusion. Myopic CNV biomarkers in women allow predicting the response to anti-VEGF therapy, the formation of relapses and the inclusion of the fellow eye in the pathological process.
The Role of Biologically Active Aqueous Humor Molecules of the Anterior Chamber and Lacrimal Fluid in the Implementation of the Hypotensive Effect of Non-Penetrating Deep Sclerectomy
Authors: Volkova N. V. , Malysheva Ju. V. , Iureva T. N. , Kolesnikov S. I.
Published: June 2021

To date, the factors affecting the course of the reparative process after non-penetrating deep sclerectomy (NPDS) have not been fully determined. There is no systematic information about the regulatory role of the cytokines TGF-β, IL-6, IL-8 and MMP-9, VEGF A 121 and 165 in the formation mechanisms of the newly created pathways consistency of intraocular aqueous humor outflow.

Purpose. To determine possible ways of impact of biologically active aqueous humor molecules of the anterior chamber and lacrimal fluid on the hypotensive effect of non-penetrating deep sclerectomy.

Methods.A prospective study of 65 patients with open-angle glaucoma before and 12 months after NPDS and 22 patients without eye hydrodynamic disorders with the determination of the initial concentrations of biologically active molecules in the lacrimal fluid and aqueous humor of the anterior chamber. Twelve months after NPDS all patients were divided into three groups, depending on the hypotensive effect of the operation, according to the criteria.

Results. Multivariate discriminant analysis showed the greatest inter-group differences, calculated by the square of the Mahalanobis distance, between group 3 with no hypotensive effect of NPDS and the control group (R2 = 8.48, p = 0.001). The most informative features that determine the differences between the 4 groups in the total population, calculated according to the Fischer F-test, were MMP-9 (F = 14.7, p = 0.001) and TGF-β (F = 7.08, p = 0.001) in the aqueous humor of the anterior chamber. In pairwise comparison of groups 1 and 2, the maximum level of significance according to the F-criterion was characteristic of the level of tear IL-6 (F = 21.25, p = 0.001), with approximately equal degree – IL-8 (F = 7.85, p = 0.001) and VEGF (F = 7.12, p = 0.001), to a lesser extent TGF of aqueous humor (F = 4.43, p = 0.001) and MMR-9 (F = 2.23, p = 0.001). Between groups 1–3, the maximum differences according to the Fisher criterion were observed in the IL-8 (F = 20.99, p = 0.001), TGF (F = 8.75, p = 0.001) and to a lesser extent – TGF (F = 5.83, p = 0.001).

Conclusion. The analysis of the obtained data showed the decisive role of the imbalance of proinflammatory cytokines, signaling proteins with prolymphoangiogenic activity, and MMP-9 in the aqueous humor of the anterior chamber, as well as in the initial state of the lacrimal fluid in the postoperative healing processes after NPDS.