bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel Therapeutic Approach to Post-Operative Adhesions: Enhancing Resident Repair Cells in the Abdomen
Authors: Obayan Adebola
Published: July 2024

Background: This study proposed to identify the possible mechanism of action of novel treatment, alanyl-glutamine (AG) in adhesion prevention. The aim was to outline the natural history of adhesion formation in a randomized animal model and to confirm the effect of peritoneal infiltration of AG on adhesion formation in rats post-laparotomy. The study also challenged the role of macrophage chemotactic protein 1 (MCP-1) on adhesion formation. Method: This study involved open abdominal surgery on 53 Wistar rats. They were assessed for AG's efficacy in preventing adhesion. Rats were randomly assigned to three groups: 1) Open laparotomy (no treatment), 2) Open laparotomy with saline, and 3) Open laparotomy with AG. Tissue explants were analyzed and assessed for fibrosis. Macrophage activity was also evaluated using ED1 and CD68 markers. Results: 6 days after surgery, severe adhesion was evident in the saline and the non-treatment group. This persisted up to day 42, while the treatment group showed minimal evidence of adhesion, with 95%-100% adhesion prevention. MCP-1 did not have a clear role in controlling macrophage infiltration. Conclusion: Our adhesion model showed a better outcome for adhesion prevention in all the rats instilled with AG after laparotomy. While MCP-1 is a marker of inflammation, it does not appear to play a role in preventing intraperitoneal adhesion, nor does it have a clear controlling role in macrophage infiltration.
Navigating Legal Framework and National Plans in Shaping the Growth of Large-scale Archaeological Sites in China
Authors: Shi Yuxin
Published: July 2024

Archaeological sites are vital carriers of human civilisation, holding immense archaeological research value and profound cultural significance. Ancient sites and tombs provide empirical evidence for Chinaʼs million-year human history, ten-thousand-year cultural history, and over five-thousand-year civilisation history, making them crucial categories of cultural relics. With the advancement of social and economic development, the understanding of the value of major archaeological sites in China has deepened. Among these, expansive archaeological sites, referred to as “major archaeological sites”, receive particular attention. The protection and utilisation of these major sites have increasingly emphasised the recognition of their cultural heritage value, widely acknowledging their significant historical, scientific, and cultural importance. For many years, the Chinese government has prioritised the protection of archaeological sites, establishing a comprehensive legal framework. The development of major archaeological sites in China is closely linked to national planning, administrative regulations, and legal statutes. Recently, the development of major archaeological sites has been further promoted as part of national planning. Based on this background, this research aims to delineate the content and evolution of the legal frameworks and national planning for the development of major archaeological sites in China. It discusses their impact on site development, using the development of major archaeological sites in Xi’an as a case study. The study focuses on these issues and provides specific recommendations from legal and administrative perspectives.
Cirurgia plástica e reparadora: inovações e desafios
Authors: Nascimento Victor Cauã Manolio , Santos Gustavo Alberto Lemes , Antunes Lucas Gambogi , Araújo Laura Santos de , Sendão Júlia Oliveira
Published: July 2024

Este estudo revisa as inovações recentes e os desafios na prática clínica da cirurgia plástica e reparadora. A análise inclui uma revisão abrangente de 45 estudos relevantes publicados entre 2014 e 2024, focando em tecnologias de imagem avançadas, técnicas minimamente invasivas, bioengenharia e medicina regenerativa. As tecnologias de imagem, como a tomografia computadorizada e a ressonância magnética, têm aprimorado o planejamento cirúrgico, enquanto a impressão 3D tem facilitado a criação de modelos anatômicos e implantes personalizados. As técnicas minimamente invasivas, incluindo o uso de lasers e robótica, têm reduzido o tempo de recuperação e melhorado os resultados estéticos. A bioengenharia e a medicina regenerativa, através de células-tronco e engenharia de tecidos, oferecem promissoras soluções personalizadas para a regeneração de tecidos e reparação de defeitos. Entretanto, a segurança do paciente permanece um desafio crucial, exigindo a implementação de protocolos rigorosos e educação contínua dos profissionais. A ética na prática da cirurgia plástica, especialmente no manejo das expectativas dos pacientes, também é uma preocupação significativa. A acessibilidade às inovações tecnológicas destaca a necessidade de estratégias para reduzir as disparidades no atendimento. A revisão conclui que, apesar dos avanços transformadores, a prática da cirurgia plástica e reparadora deve continuar a evoluir, abordando os desafios de segurança, ética e acessibilidade. A combinação de excelência técnica, segurança do paciente e prática ética é fundamental para o sucesso contínuo desta especialidade, promovendo benefícios duradouros e significativos para os pacientes.
The Utilization of European Experience in the Formation of Professional Competencies of Future Specialists of the Ukrainian Vocational Education System
Authors: Bertash Mariia , Polishchuk Svitlana , Burdun Viktor , Ivanyshyn Nataliia , Zhulkovskyi Vadym
Published: July 2024

The modern integration of European standards into the Ukrainian education system is a topical process that requires a detailed study due to the peculiarities of implementation against the background of extreme circumstances. The purpose of the article is to analyze the application of European experience in the formation of professional competencies of future specialists in vocational education systems in Ukraine. The realization of this goal involved the use of a system of scientific methods. In particular, using the method of content analysis, the modern and relevant scientific literature on this issue was analyzed. The coding method was used to find it, and the texts were processed using synthesis and comparison. The results show that the use of European experience in the formation of professional competencies in the system of vocational education in Ukraine has influenced the training of qualified students. The application of the leading European experience has made it possible to integrate the standards of the leading countries into the Ukrainian educational environment. Based on the analysis, it was found that the movement to update the content of the professional world in Europe began in the 1990s and accelerated as a result of the Bologna system. Ukraine joined global trends in the early 2000s, although some elements were introduced in the mid-2010s. The use of best practices has expanded the importance of the competency-based approach in Ukrainian education and allowed for a focus on training specialists in demand on the labor market. The use of European experience in vocational education has updated the mechanisms of partnership between all participants in the educational process, forming innovative and practice-oriented curricula. The conclusions indicate that in Ukraine, the use of European experience has allowed stakeholders to actively engage in the reorganization of the educational process, to focus education on the applicant and his or her requirements.
Peptides and Cancer
Authors: Covenas Rafael
Published: July 2024

Peptides exert oncogenic or anticancer effects on many cancer types and, compared with normal cells, cancer cells overexpress peptide receptors. Overexpression of the peptidergic systems (peptides and/or peptide receptors) by tumors has been related with tumor size, relapse risk, aggressiveness, and poor prognosis. This overexpression serves as tumor biomarker for diagnosis/treatment and opens the door to use compounds favoring a more specific destruction of cancer cells than the anticancer strategies currently used in clinical practice. Oncogenic peptides favor the proliferation, invasion, migration and metastasis of tumor cells, exert an anti-apoptotic action in these cells, and promote lymphangiogenesis and angiogenesis, therefore favoring tumor development, whereas peptide receptor antagonists counteract all the previous oncogenic effects [1]. Different tumor types overexpress the same peptide receptor and this suggests that the same antitumor strategy (e.g., peptide receptor antagonists, peptide receptor radionuclide therapy, cytotoxic peptide conjugate-based cancer therapy) could be applied to treat different cancers. Anticancer peptides exert antiproliferative, apoptotic and antimigration actions in cancer cells as well as anti-angiogenic effects; that is anticancer peptides and peptide receptor antagonists exert the same antitumor actions. Peptides receptor antagonists show a high therapeutic capacity because peptides/peptide receptor agonists have poor bioavailability and short half-life, although the latter compounds have a higher solubility and safety. However, many strategies to increase the therapeutic effect of peptides, their delivery and stability have been developed [2]. Peptides and peptide receptor antagonists are therapeutic tools to fight cancer and hence ligands and receptors of the peptidergic systems open the door to develop new, specific and promising anticancer strategies. In fact, the Food and Drug Administration (FDA) has approved gonadotropin-releasing hormone receptor agonists to treat breast and prostate cancers and somatostatin peptide analogs for diagnostic and treatment purposes in tumors expressing somatostatin receptors (e.g., lung, neuroendocrine) [2]. Moreover, the repurposing of the antiemetic drug aprepitant (a neurokinin-1 receptor antagonist) as anticancer agent has been suggested [3]. This confirms the important roles that peptidergic systems play in cancer progression and how the current knowledge on these systems can be applied in clinical practice because peptidergic systems are crucial therapeutic targets for cancer treatment [4].
Phép chiếu dùng cho bản đồ hành chính cấp tỉnh
Authors: Đồng Thị Bích Phương
Published: July 2024

Bài báo làm rõ một số yếu tố ảnh hưởng đến việc lựa chọn phép chiếu dùng cho bản đồ hành chính và đề xuất sử dụng phép chiếu hình trụ ngang đồng góc với k = 0,9999, kinh tuyến trục địa phương cho bản đồ hành chính từ cấp tỉnh trở xuống.
A study of availability and utilization of personal protective equipment among healthcare workers of a tertiary institution in South-west, Nigeria.
Authors: Bakare Omowunmi , Aniaku Ifeoma
Published: July 2024

Background: Healthcare settings pose a significant risk to healthcare workers due to various
workplace hazards. Personal protective equipment (PPE) remains a potent strategy for preventing workplace hazards. Despite the widely known importance of PPE, studies have shown that its availability and use may need to be revised. This study investigated the availability and utilisation of PPE among healthcare workers in Babcock University Teaching Hospital, Ogun State.
Methods: A descriptive cross-sectional study was conducted among 350 healthcare workers using a stratified proportionate sampling technique. Data was obtained and analysed using IBM SPSS software version 25. Descriptive (frequency tables and summary indices) and inferential statistics
(Chi-square test) were generated. Chi-square was used to test and determine any significant association between the categorical variables. The level of statistical significance is set at p<0.05.
Results: More than half (53.4%) of respondents were aged between 21–30 years, (64.3%) were females, and (43.4%) were nurses. Most (87%) had a high awareness of workplace hazards. All (100%) respondents reported the availability of hand gloves, while (60%) used PPE every time. The
majority (85.7%) of respondents had good-fitted PPE, while (79.7%) claimed to have experienced occupational injury in the past, but (70.9%) received treatment. There was a statistically significant association between awareness of workplace hazards, availability (P=0.001), and utilisation
(P=0.0001) of PPE.
Conclusion: The availability of PPE was optimal. However, it was only sometimes used when carrying out a procedure. Hence, more organisational efforts should be geared towards optimally utilising PPE in the workplace.
ASSESSMENT OF THE CONCENTRATIONS OF ACTIVE PRINCIPLE CONTENT IN SOME BRANDS OF ERYTHROMYCIN PRODUCTS AVAILABLE FOR VETERINARY USE IN MAIDUGURI, NORTHEASTERN NIGERIA
Authors: Maina Umar , Adaweren Emmanuel , Ngulde Saidu , Umaru Bukar
Published: July 2024

ABSTRACT
Erythromycin, a broad-spectrum macrolide antibiotic, is one of the commonly used drugs in veterinary practice for the treatment of various forms of bacterial infections. It essentially acts by inhibiting bacterial protein synthesis. The increased number of pharmaceutical companies in Nigeria and globally has resulted in the production of numerous substandard drugs which can be attributed to poor quality control by the relevant regulatory agencies.
Aims
This study aimed to quantifies the active principle (compound) in various erythromycin brands marketed within Maiduguri and its environs.
Method
Structured Questionnaires were also administered to 3 categories (Veterinarians, Drug Vendors, and Farmers) of respondents used for this study. Questions concerning the respondent’s demography, years of experience, preferences in use of erythromycin over other antibiotics and frequency of usage are among other questions asked during this study. Five different erythromycin brands labeled A – E were analyzed using the spectrophotometer method. These 5 samples were measured against a standard erythromycin sample (Sigma-Aldrich E5389) obtained from the National Agency for Food and Drugs Administration Control (NAFDAC).
Results
The results showed that sample C contained 59% of the active constituent written on its label. Samples B and A contained 88% and 89% of the active constituents on their labels, while samples D and E contained 173% and 101% respectively of the active constituents indicated on their labels.
Conclusion
It might be inferred that there has been significant variability in the concentration of active component among the various brands of erythromycin employed in this investigation.
Violence experiences and solution approaches healthcare workers in emergency department
Authors: Gurdap Zuleyha , Komurkara Sema , Cengiz Zeliha
Published: July 2024

The study aimed to evaluate the prevalence of violence against healthcare workers in emergency departments and identify solution approaches. The research, utilizing a descriptive design, was conducted with 149 health workers employed in the emergency units of a research hospital. Data were collected using a survey form constructed based on the literature. Participants' 92.6% experienced some form of violence, with 92.8% of these individuals subjected to verbal abuse. The main causes of violence were identified as the perpetrator justifying their behaviour (42.0%), refusal of requests such as prescriptions or reports (50.0%), and dissatisfaction with treatment (41.3%). 40.6% of health workers filed a code white report, and 36.2% stated that no action was taken against the aggressor.83.9% of health workers indicated that legislation, 70.5% code white, and 55.0% reported inadequate security measures. Health workers suggested implementing deterrent penalties (18.1%) and increasing security measures (17.4%) to reduce violence. A significant difference was found between professional experience and exposure to violence, as well as the types of violence encountered. Additionally, an important significant difference was identified between the profession and the gender of the perpetrator of violence. While physicians and other professional groups are generally subjected to violence by men, nurses and midwives experience violence from both women and men, as well as both genders together (p<0.05). The study found that emergency department health workers face high rates of violence and existing measures are inadequate. In this context, it is recommended to review existing legal regulations, ensure continuous and visible security, and enhance the effectiveness of code white protocols.
From Tangible to Digital: How Will Digital Assets Integrate with Investment Treaties
Authors: Huber Kevin J.
Published: July 2024

As we approach the first quarter mark of the twenty-first century, we have seen the expansion of the definition of a protected investment in investment treaties. While many investment treaties were signed at a time when only physical investments were contemplated, as our modern technological industrialists continue to rapidly push innovation forward and write the code for new digital assets, our understanding of what a protected investment is may also be innovated. Yet, the definition of a digital asset and whether it can be considered a protected investment under an investment treaty remain difficult questions. This article seeks to contribute to an ongoing debate about the meaning and scope of protected investments under investment treaties and in particular whether an entirely intangible digital asset can exist within the territory of a host State.
The planning method: An inquiry into the constitutional ramifications of a new EU governance technique
Authors: Dermine Paul
Published: July 2024

The past few years have been marked by a strong return of public authorities in economic affairs, and the emergence of new forms of economic activism. From a governance perspective, this has come together with the retour en grâce of planning as a public policy approach. With initiatives such as the Green New Deal or the recovery plan NextGeneration EU, the EU has certainly not been immune to this trend. This article conceptualizes this planning method that is emerging as a novel EU governance technique, and a central vehicle for new European policies. Although not without precursors, the planning method embodies a highly proceduralized, country-specific, bilateral, executive and performance-based governance template, which clearly breaks away from the Union’s traditional approaches to policy making.The planning method opens up new horizons for EU integration, and its benefits in terms of national ownership and policy effectiveness seem quite real. It is also inherently disruptive, and poses new risks, new challenges for the Union and its constitutional foundations, which this article investigates. As a hybrid, “Euronational” phenomenon, the planning method blurs power distribution and responsibility allocation in the EU and stands as an important source of constitutional uncertainty. It rests on a highly technocratic and managerial approach to planning and impacts institutional balances in the EU. It puts pressure on the integrity of the rules, principles and objectives the very pursuance of which it is to promote. Lastly, the planning method also accelerates de facto differentiation in the EU and relativizes the scope of national sovereignty in the Union, raising concerns for State equality.
Evaluation of the likelihood of detection of porcine epidemic diarrhea virus or porcine delta coronavirus ribonucleic acid in areas within feed mills
Authors: Greiner Laura
Published: July 2024

Objective: To compare areas within feed mills to determine the likelihood of presence of either porcine epidemic diarrhea virus (PEDV) or porcine delta coronavirus (PDCoV). Materials and methods: Twenty-four feed mills from various regions in the United States were evaluated. Swab samples (foot pedals of feed delivery trucks, bulk ingredient unloading pits, inside the mixer or pellet coolers, mill office floors, inside feed compartments on feed trucks and incoming bagged-ingredient trucks) were collected daily at each feed mill for up to 5 days. The samples were submitted for polymerase chain reaction testing for PEDV and PDCoV. Results: Of the feed mills tested, 75% were supplying feed to known PEDV-positive herds, and 21% were supplying feed to known PDCoV-positive herds. No samples at any mill tested positive for PEDV ribonucleic acid (RNA), although 5% of the truck foot pedals and 1% of the bulk-ingredient pits tested suspect. Porcine delta coronavirus RNA was found on 3.4% of the foot pedals of the trucks, and 2.2% of the office floors tested suspect. Implications: Porcine delta coronavirus RNA can be detected at different locations around feed mills. Feed mill biosecurity protocols need to be evaluated and maintained to minimize the probability of PEDV and PDCoV RNA presence.
The effect of antiseptic compounds on umbilical cord healing in piglets in a commercial facility
Authors: Robinson Amanda , Colpoys Jessie , Robinson Glenn , Hines Elizabeth , Timms Leo , Edwards Erika , Stalder Ken , Johnson Anna , Tyler Howard
Published: July 2024

Four hundred and seventy piglets were assigned to four treatment groups: iodine, trisodium citrate, a dry dip created using nisin with talc, and no treatment. No treatment differences were noted on change in diameter or incidence of infection of the umbilical cord during the first 48 hours (P > .05).
Projected Future Scenario of Electric Vehicles and Their Latent Impact on Electricity Demand in Kenya
Authors: Kipsang Rogers ,   Department of Physics, University of Eldoret, Cherus David C , Tonui Joel K ,   Department of Physics, University of Eldoret,   Department of Physics, University of Eldoret
Published: July 2024

Abstract-This study projects the future scenario of electric vehicle (EV) adoption and its impact on electricity demand in Kenya. Using data from the Kenya National Bureau of Statistics on EVs and internal combustion engine vehicles (ICEVs) registered from 2010 to 2022. Logistic growth model (LGM) used for projections was executed using MATLAB. The projected number of EVs by 2050 for conservative (25%) moderate (50%), optimistic (75%), and original (100%) adoption rates were respectively 3,927,131; 7,475,274; 9,880,293 and 10,807,843 with corresponding electricity demand of 14.8 TWh, 28.2 TWh, 37.3 TWh and 40.8 TWh, which increases to 18.7 TWh, 35.7 TWh, 47.2 TWh, and 51.6 TWh when generation and transmission losses are added. Adding electricity demand by other sectors, net electricity generation increases in the range from 37.4 TWh to 70.3 TWh for conservative and original scenarios respectively by 2050, which represent 3-times and 5.5 times the 2022-generation of 13 TWh. In conclusion, EVs penetration into the Kenyan market is currently low. However, their eventual replacement of ICEVs will have significant implications for electricity demand and supply, even under the conservative scenario. Key Words: transportation, electric vehicles, energy demand, logistics growth model, climate change
Heart Disease Prediction Using Machine Learning
Authors: Yadav Shivani ,   Department of Computer Science and Engineering Dr. Ram Manohar Lohia Avadh University, Ayodhya
Published: July 2024

Heart disease remains a leading cause of mortality worldwide, necessitating improved methods for early detection and risk assessment. This paper reviews and analyzes the application of machine learning techniques in heart disease prediction, focusing on five primary algorithms: Naïve Bayes, k-Nearest Neighbor (KNN), Decision Tree, Artificial Neural Network (ANN), and Random Forest. By examining existing studies and datasets, we evaluate the effectiveness of these algorithms in predicting heart disease risk. Our analysis demonstrates that machine learning models can significantly enhance the accuracy and efficiency of heart disease prediction compared to traditional diagnostic methods. The Random Forest algorithm exhibited the highest overall performance, with studies reporting accuracy rates up to 95% in identifying potential heart disease cases. This review highlights the potential of machine learning in revolutionizing cardiovascular healthcare by enabling more personalized risk assessments and facilitating early intervention strategies. The integration of these advanced predictive models into clinical practice could substantially improve patient outcomes and reduce the global burden of heart disease. Keywords: Cardiovascular Risk Prediction, Machine Learning Algorithms, Electronic Health Records, Random Forest, Artificial Neural Networks, Feature Importance, Clinical Decision Support, Personalized Medicine, Predictive Analytics in Healthcare, Early Disease Detection.
Accident Prevention System
Authors: MANIGANDAN DR. S. K
Published: July 2024

Accident prevention system represents a groundbreaking innovation in vehicular safety technology. This advanced system integrates cutting- edge technologies such as eye blink sensors, GPS modules, Arduino and GSM communication to detect and mitigate potential hazards during driving. The accident prevention system incorporates a GPS module, enabling precise location tracking and providing crucial data for emergency responders. The integration of these technologies aims to significantly reduce the risk of accidents caused by driver inattention, fatigue, or other safety-critical factors. This abstract outline the comprehensive approach of accident prevention system, highlighting its potential to revolutionize road safety by leveraging state-of-the-art sensor technologies and intelligent communication systems. Key Words: Eye blink sensor, Arduino, GPS Module, GSM Module.
Effect of Sacral Warm Compress on Perception of Labour Pain among Parturient Mothers during First stage of Labour at Selected Hospital, Coimbatore
Authors: Nirmala Dr.T
Published: July 2024

An interventional study was conducted to assess the effect of sacral warm compress on the perception of labour pain among parturient mothers during the first stage of labour at Sri Ramakrishna Hospital, Coimbatore. Quasi- experimental pre-test post-test control group design was adopted for the study. Purposive sampling method was used and 40 parturient mothers were included based on inclusion and exclusion criteria. Every alternative sample was assigned to experimental group [n=20] and control group [n=20]. The pre-test was conducted to assess the perception of labour pain by using questionnaire and numerical pain rating scale. Sacral warm compress was applied for 20 minutes at every 1-hour interval during the active phase of the first stage of labour. The post-test was conducted using the same tool to find the effect of sacral warm compress on parturient mothers during the first stage of labour. The mean and standard deviation pre-test and post-test pain score of mothers in the experimental group were (7.13, 5.09) and 0.849, 0.875 respectively with a mean difference of 2.04. It proves that there is an effect of sacral warm compress on the perception of labour pain among parturient mothers in the experimental group (t= 3.883; p=0.001). The mean and standard deviation of post test scores of mothers in the experimental and control group were 5.09, 7.495 and 0.875, 0.467 respectively with a mean difference of 2.405. It proves that there is an effect of sacral warm compress on perception of labour pain among parturient mothers in experimental group (t=10.48; p = 0.001). The findings reveal that application of sacral warm compress is highly significant and effective in reducing the perception of labour pain among parturient mothers during active phase of the first stage of labour. Keywords: Parturient Mothers during first stage of labour, Perception of labour pain, Sacral Warm Compress.
Real-Time Network Traffic Analysis and Anomaly Detection to Enhance Network Security and Performance: Machine Learning Approaches
Authors: Jakkani Anil Kumar
Published: July 2024

There are numerous proceedings that take place within an actual computer network, and one of them is the monitoring of the network traffic in real-time with the added function of anomaly detection. This research focuses on the use of machine learning to improve these capabilities as stated in the following section. In the context of the current study, the emphasis is made of building powerful anomaly detection models that would be capable to work in real life by defining network and potential threats on their own due to their machine learning capabilities. Furthermore, the study gives a detailed analysis of the more complex methods like feature selection in addition to dimensionality reduction for enhancing the abilities of machine learning algorithms in the management of big data samples for world-wide network traffic. Furthermore, the presented research focuses on the application of definitions of edge computing paradigms to facilitate decentralized processes of the identification of anomalies, thereby enhancing the sensitivity and response time of essential networks. Thus, the research objectives are to address the aforelisted challenges and generate insights into constructing better network security frameworks to prevent and respond to future threats in a precise and effective mechanism.
Superlatives and definiteness
Authors: Giurgea Ion
Published: July 2024

Previous research on superlatives in Romance languages has established three major types: (i) in Italian and Ibero-Romance, the definite article does not form part of the superlative, except for modal superlatives; (ii) in French, a definite article form functions as a superlative marker in some positions (DP-external, quantity and postnominal superlatives) but not in prenominal superlatives; (iii) in Romanian, the marker cel, historically identical to the strong definite article form, has been generalized as a superlative marker. I investigate the distributional and semantic correlates of this threefold distinction. I argue that in Romanian prenominal superlatives may sit in SpecDP, which explains the availability of relative readings, whereas in types (i) and (ii) they sit in a dedicated SpecSupP position, which is a scope position. Moreover, the existence of an overt marker allows Romanian prenominal superlatives to combine with determiners other than the definite D. The restrictions on the distribution of DP-external and quantity superlatives in type (i) are analyzed using a specific version of Heim’s (1999) raising analysis. Finally, I discuss the consequences of the data of Romance for the general debate concerning relative superlatives.
Relationship between Pedagogical Approaches and Socio-Emotional Development of Students in Early Childhood Education
Authors: Babar Mahjabeen , Aslam Sadia , Yousuf M. Imran , Parveen Nazia , Jafari Saiyida Masooma
Published: July 2024

Socio-emotional development is the process in which students acquire awareness of themselves, interpersonal skills, and decision-making abilities, which are required for success in the classroom, workplace, and life. Normally, schools keep putting more emphasis on learning through rote learning, and socio-emotional skills are overlooked. This study was designed to determine the association between socio-emotional development and pedagogical strategies. The study was descriptive and delimited to the private ECE schools in Rawalpindi. The target population of the study was comprised of all instructors from private ECE institutes. A purposive sampling technique was applied to select forty teachers from twenty private ECE schools. Observational checklists for teachers were self-developed and pilot-tested. The face and content validity of the scale was improved through experts' opinions. Data was collected from teachers personally by the researcher. Researchers spent three-month time for data collection. Data was analyzed by using descriptive statistics and correlation. The findings indicated a positive relationship between pedagogical approaches and the students' socio-emotional development. The effectiveness of these teaching methods for enhancing students' socio-emotional development was found. The study recommends that teachers should encourage games-based activities to utilize the relationship skills of pupils at the early childhood level.
THE INFLUENCE OF SERVICE QUALITY AND COMPETENCY ON EMPLOYEE WORK EFFECTIVENESS AT LAUNDRY IN PERCUT SEI TUAN DELI SERDANG DISTRICT
Authors: Karim Ahmad ,   Universitas Pembinaan Masyarakat Indonesia
Published: July 2024

The objectives of this research are to determine the magnitude of the influence of service quality on employee work effectiveness at Laundry in Percut Sei Tuan District, Deli Serdang Regency, determine the magnitude of the influence of competency on employee work effectiveness at Laundry in Percut Sei Tuan District, Deli Serdang Regency, determine the magnitude of the influence of service quality and competence on the work effectiveness of employees at the Laundry in Percut Sei Tuan District, Deli Serdang Regency simultaneously. The number of samples used was 80 people from laudry in Percut Sei Tuan District, Deli Serdang Regency. The analytical method used was quantitative analysis with the help of the SPSS Version 23 program. Research results: Based on the results of hypothesis testing, service quality is proven to have no significant effect on employee work effectiveness. From the hypothesis test, it shows that there is a very small effect, namely 16.5% and the significance value obtained is greater than 0.05, which means the effect is not significant. This can be explained that the dimensions of service quality include: physical evidence, reliability, responsiveness and guarantees which are not able to reflect service quality in influencing employee work effectiveness. Based on the results of hypothesis testing, competence is proven to have a significant effect on employee work effectiveness, the magnitude of the influence of competence on employee work effectiveness is 73.2%, this effect is classified as high. Based on the results of hypothesis testing, service quality and competence together have been proven to have a significant effect on employee work effectiveness. The magnitude of the influence of service quality and competence together on employee work effectiveness is 76.4%, this effect is classified as high.
“Fast” food for thought? Exploring the not-so-easy-to-digest language of Albanian newspapers
Authors: Qafzezi Eriola
Published: July 2024

Pressured to increase their market share and capture more people’s attention, newspapers are under influence. The search for sensationalist exclusivity leads to uniformity and rudeness. For the purpose of this article, several Albanian newspapers were examined in order to find out how the news are produced or « constructed ». We found a tendency to hide rather than publicize news, offering selected and readymade news that require little effort of hindsight and analysis. This dynamic reveals the deterioration of the conditions of access of the public to information allowing to question the politico-media news. The text ends with a call to reconnect with the journalistic ideal.
Dinâmica espaço-temporal da paisagem da Área de Proteção Ambiental do Ibirapuitã no bioma Pampa, Rio Grande do Sul
Authors: Silva Pedro Seeger da , Milagre Jocimar Caiafa , Mendes Lucas José , Fantinel Roberta Aparecida , Granzotto Fabiane , Pereira Rudiney Soares
Published: July 2024

As unidades de conservação (UC) apresentam papel crucial na manutenção da biodiversidade e serviços ecossistêmicos. A gestão e o planejamento territorial desses ambientes podem ser aprimorados com base no entendimento das mudanças na configuração e estrutura da paisagem. Objetivou-se neste estudo avaliar a dinâmica espaço-temporal de uso e ocupação do solo da APA do Ibirapuitã por meio de métricas de ecologia da paisagem. Foi utilizada a coleção 8 do Projeto Mapbiomas para avaliar as classes de uso e ocupação do solo em 2002 e 2022 e o cálculo das métricas foi realizado a partir da extensão LecoS no QGIS. As classes formação campestre, formação florestal e agropecuária foram as mais representativas em área nos anos analisados. Nas formações nativas, houve redução de 2,3% na área total da classe de formação campestre e um aumento de 7,4% na formação florestal no período avaliado. Ao mesmo tempo, a agropecuária aumentou quase 40%. Diferente da agropecuária, o número de fragmentos e densidade de borda aumentaram para as formações campestre e florestal, com diminuição na distância média do vizinho mais próximo. A redução relativamente pequena na área de formação campestre e o aumento da formação florestal e outras formações não florestais reforçam a importância da APA do Ibirapuitã para a conservação da vegetação nativa do Pampa e apontam para a importância da criação de novas UC no bioma. Os resultados do estudo podem auxiliar na implementação de medidas de gestão e desenvolvimento de políticas públicas voltadas à conservação ambiental desta região.
Prática docente em uma escola do ensino fundamental em Rondônia após 30 anos da institucionalização da Educação Ambiental no Brasil
Authors: Matos Elieude Bacelar , Simão Maria Olívia de Albuquerque Ribeiro
Published: July 2024

Diante da crise socioambiental que nosso planeta enfrenta, a Educação Ambiental (EA) se destaca como uma resposta essencial para fomentar a sustentabilidade e moldar cidadãos responsáveis e conscientes. Dentro das escolas, a EA deve ser integrada de maneira que abranja todas as disciplinas, promovendo uma visão ampla e interconectada das questões ambientais. Educadores desempenham um papel vital nesse processo, atuando não apenas como facilitadores do conhecimento, mas também como exemplos de atitudes sustentáveis e inspiradores de mudança. A pesquisa tem como objetivo geral analisar como ocorre a prática docente na promoção da Educação Ambiental em uma escola localizada em área periférica da cidade de Porto Velho – RO. No percurso metodológico, de caráter qualitativo, empregaram-se pesquisa documental, entrevistas semiestruturadas com 18 professores, além de análise de conteúdo. Os resultados indicam que as práticas educacionais ambientais não são conduzidas conforme preconizam as políticas e diretrizes da EA no Brasil. A maioria dos professores, com mais 20 anos de carreira e 10 anos de formados, não tiveram na formação inicial o componente curricular de Educação Ambiental. Tão pouco obtiveram formação continuada em, mesmo transcorridos 24 anos de implementação da PNEA. Esses professores abordam as questões ambientais por meio de sensibilização e atividades lúdicas de forma genérica e pontual a partir de temas como: reciclagem, lixo, poluição das águas. Não incorporam ainda de forma sistemática e contínua a Educação Ambiental em sua prática pedagógica, restringindo as abordagens a atividades pontuais, principalmente em datas comemorativas. O PPP da escola estudada, revisado em 2019, também não faz nenhuma menção aos desafios ou temas ambientais, ou sequer, cita leis, normas, diretrizes relacionadas à Educação Ambiental. Esta pesquisa nos faz refletir que, mesmo após 30 (trinta) anos da CF Brasileira instituir o direito à EA e mais de 20 anos da PNEA definir a EA na educação escolar, ainda existem no país escolas que necessitam implementar as políticas educacionais ambientais em conformidade com o que está estabelecido nos marcos legais e orientativos da EA no Brasil.
Macrofauna edáfica como bioindicadora da qualidade ambiental no perímetro do reservatório negreiro, Pernambuco, Brasil
Authors: Rodrigues Francisco Welde Araujo , Azevedo Francisco Roberto de , Carneiro Ana Alice Cardoso , Oliveira Carolina da Silva de , Silva Jaqueline de Melo Santos , Patricio Everton Alencar , Azevedo Raul , Ferreira Raimundo Nonato Costa
Published: July 2024

A macrofauna edáfica é uma importante bioindicadora da qualidade ambiental dos ecossistemas devido à sua diversidade e resposta eficaz aos distúrbios ambientais. Este estudo visou inventariar e avaliar a influência da macrofauna edáfica como indicadora ambiental no reservatório Negreiros, localizado em Salgueiro, no Sertão Central de Pernambuco, parte do Projeto de Integração do Rio São Francisco com as Bacias do Nordeste Setentrional. Foram estudadas duas áreas distintas: uma preservada e outra antropizada, ambas de 500 x 50m. A coleta de dados ocorreu em períodos de seca (julho a dezembro de 2022) e chuvoso (janeiro a junho de 2023) utilizando armadilhas de solo tipo pitfall. Foram coletados 13.216 espécimes pertencentes a três classes e 11 ordens, sendo as mais abundantes: Coleoptera, Blattodea, Orthoptera, Diptera e Hymenoptera. Durante o período seco, houve predominância de 10.903 espécimes distribuídos em 11 ordens, enquanto no período chuvoso foram registrados 2.313 espécimes em oito ordens. As famílias mais abundantes e constantes foram Formicidae, Tenebrionidae, Scarabaeidae, Gryllotalpidae, Gryllidae e Blattidae, indicando condições ambientais relativamente boas nas áreas estudadas. Em resumo, os resultados indicam que a macrofauna edáfica do reservatório Negreiros pode fornecer informações valiosas sobre a qualidade ambiental, destacando áreas com potencial conservacionista devido à sua relação direta com o solo e a serrapilheira, essencial para a sobrevivência e reprodução desses insetos.
Acute Acalculous Cholecystitis as a Rare Initial Presentation of Epstein-Barr Virus Infection in an Immunocompetent Adult Female
Authors: Güven Alper Tuna , Çevirici Burak , Gürsoy Gamze
Published: July 2024

Epstein-Barr virus (EBV) infection is a self-limited disease usually characterized by a sore throat, fever, and lymphadenopathy. Mild to moderate hepatitis may also occur during the course of the infection. The disease is very rarely complicated with acalculous cholecystitis. Herein, we report a 22-year-old immunocompetent female patient who initially presented with fever and moderate abdominal pain that was revealed to be due to acute acalculous cholecystitis. The EBV infection was diagnosed both clinically and serologically. Typical findings of sore throat and cervical lymphadenopathy appeared later the fifth day of admission. In this case report, the patient was treated conservatively, without surgery. Atypical presentation, inverse timing of clinical manifestations, and the conservative management of acalculous cholecystitis in contrast to critically ill patients’ acalculous cholecystitis management are noteworthy for both surgeons and internists to be aware of.
An Independent Predictor of Mortality in Hospitalized Patients: Vitamin B12
Authors: Çavuşoğlu Betül , Solmaz Kübra , Türker Fatih , Ataoğlu Esra
Published: July 2024

Objectives: Increased vitamin B12 levels are associated with mortality. We aim to define the relationship between B12 levels and 6 months,12 months, and 48 months mortality.
Methods: We investigated 455 patients hospitalized in the internal medicine clinic from 01.01.2014 to 30.06.2014. Patients younger than 18 years old, with chronic heart failure, hematological malignancies, solid tumors, chronic liver disease, and end-stage kidney disease were excluded. Patients with a vitamin B12 below and below the reference range were excluded. Laboratory parameters and vitamin B12 levels were compared between survival and non-survival groups at 6 months,12 months, and 48 months. Mortality data for 6 months,12 months, and 48 months after the first hospitalization day were obtained.
Results: The mortality percentages of patients were evaluated on the 6th, 12th, and 48th months. Age, complete blood count parameters (hemoglobin, white blood cell, and platelet), acute phase reactants, and serum vitamin B12 levels were compared between patient groups. Increased vitamin B12 level was found to be correlated with acute phase reactants (C reactive protein, albumin, ferritin, sedimentation) and hemoglobin. Regression analysis revealed that increased vitamin B12 levels, ferritin, sedimentation, white blood cell, and low albumin levels were statistically significant in 6th-month mortality. High white blood cell count and low albumin levels were statistically significantly correlated with mortality in the 12th and 48th months.
Conclusion: Increased vitamin B12 levels were effective in predicting 6-month, 12-month, and 48-month mortality. Age-decreased albumin levels, acute phase reactants, and increased B12 levels were identified in hospitalized patients as risk factors for short, mid-term, and long-term mortality.
Detection of antinuclear antibodies: recommendations from EFLM, EASI and ICAPEFLM Paper
Authors: Bonroy Carolien , Vercammen Martine , Fierz Walter , Andrade Luis E.C. , Van Hoovels Lieve , Infantino Maria , Fritzler Marvin J. , Bogdanos Dimitrios , Kozmar Ana , Nespola Benoit , Broeders Sylvia , Patel Dina , Herold Manfred , Zheng Bing , Chan Eric Y.T. , Uibo Raivo , Haapala Anna-Maija , Musset Lucile , Sack Ulrich , Nagy Gabor , Sundic Tatjana , Fischer Katarzyna , Rego de Sousa Maria-José , Vargas Maria Luisa , Eriksson Catharina , Heijnen Ingmar , García-De La Torre Ignacio , Carballo Orlando Gabriel , Satoh Minoru , Kim Kyeong-Hee , Chan Edward K.L. , Damoiseaux Jan , Lopez-Hoyos Marcos , Bossuyt Xavier
Published: July 2024

Aim: Antinuclear antibodies (ANA) are important for the diagnosis of various autoimmune diseases. ANA are usually detected by indirect immunofluorescence assay (IFA) using HEp-2 cells (HEp-2 IFA). There are many variables influencing HEp-2 IFA results, such as subjective visual reading, serum screening dilution, substrate manufacturing, microscope components and conjugate. Newer developments on ANA testing that offer novel features adopted by some clinical laboratories include automated computer-assisted diagnosis (CAD) systems and solid phase assays (SPA).

Methods: A group of experts reviewed current literature and established recommendations on methodological aspects of ANA testing. This process was supported by a two round Delphi exercise. International expert groups that participated in this initiative included (i) the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group "Autoimmunity Testing"; (ii) the European Autoimmune Standardization Initiative (EASI); and (iii) the International Consensus on ANA Patterns (ICAP).

Results: In total, 35 recommendations/statements related to (i) ANA testing and reporting by HEp-2 IFA; (ii) HEp-2 IFA methodological aspects including substrate/conjugate selection and the application of CAD systems; (iii) quality assurance; (iv) HEp-2 IFA validation/verification approaches and (v) SPA were formulated. Globally, 95% of all submitted scores in the final Delphi round were above 6 (moderately agree, agree or strongly agree) and 85% above 7 (agree and strongly agree), indicating strong international support for the proposed recommendations.

Conclusions: These recommendations are an important step to achieve high quality ANA testing.
Unraveling the Relation between the Language's Pedagogical Complex Tapestry and Communicative Competence
Authors: Ciesielski Jerzy
Published: July 2024

The article delves into the nuanced relationship between language, philosophy, and communication, examining perspectives from Wittgenstein to Chomsky. It navigates linguistic functions, emphasizing the interplay between communication and representation. From the roots of the term "communication" to Sapir-Whorf's linguistic relativism, the article underscores language's triple role in culture. It addresses contextual layers in communication, exploring language's cognitive and cultural dimensions. Models by Jakobson, Ogden-Richards, and Austin, along with the evolution of communicative competence, are succinctly outlined. In essence, the article offers a concise exploration of language's intricate role in shaping human understanding and interaction. In the realm of glottodidactics, the study of language teaching and learning, the exploration reveals a dynamic evolution influenced by linguistic theories and broader socio-cultural shifts. The article highlights that the field adapts to technological, economic, and political changes, therefore glottodidactics continues to navigate the complexities of language pedagogy.