bluuebunny/crossref_metadata_2025 huggingface dataset:
МОДЕРНИЗАЦИЯ СИСТЕМЫ МЕДИЦИНСКОГО ПРАВА В УЗБЕКИСТАНЕ: БАЛАНС МЕЖДУ МЕЖДУНАРОДНЫМИ СТАНДАРТАМИ И НАЦИОНАЛЬНЫМИ ОСОБЕННОСТЯМИ ЗДРАВООХРАНЕНИЯ
Authors: Ёкубов Шухратжон , Эргашева Муниса
Published: February 2025

Статья посвящена анализу процесса модернизации системы медицинского права в Узбекистане. Рассматриваются международно-правовые основы регулирования медицинской деятельности и специфика отечественной системы здравоохранения. Выделены ключевые направления совершенствования медицинского законодательства: укрепление юридического статуса пациента, развитие регулирования в отношении медицинских работников, применение инновационных методов, управление качеством, государственно-частное партнерство. Отмечены вызовы реализации нормативных новелл. Подчеркивается необходимость консолидации усилий государства и общества для успешной модернизации медицинского права.
RAQAMLI TRANSFORMATSIYALAR SHAROITIDA YOSHLARNING AXBOROT XAVFSIZLIGI MADANIYATI VA MEDIAIMMUNITETINI TAʼLIM JARAYONLARI ORQALI SHAKLLANTIRISH MASALALARI
Authors: Karimov Akramjon
Published: February 2025

Maqolada raqamli transformatsiyalar sharoitida yoshlarning axborot xavfsizligi madaniyati va mediaimmunitetini taʼlim jarayonlari orqali shakllantirishning dolzarb masalalari yuzasidan olib borilayotgan tadqiqot natijalari keltirilgan. Xususan, ijtimoiy-gumanitar taʼlim yoʻnalishidagi oʻquv fanlarining yoshlarimizda axborot xavfsizligi madaniyatini yuksaltirishdagi, mediaimmunitetni shakllantirish va mustahkamlashdagi oʻrni va vazifalari oʻrganilgan. Mavzuga oid muammolar tizimli ekani taʼkidlangani holda, ular uchun muayyan yechimlar taklif etilgan.
BOSHLANGʻICH SINFLARDA MATEMATIKANI OʻQITISHNING HOZIRGI HOLATI
Authors: Nasriddinova Hulkar
Published: February 2025

Ushbu maqolada boshlangʻich sinflarda matematikani oʻqitishning hozirgi holatini tahlil qilingan. Shu bilan bir qatorda maqolada yangi oʻquv dasturlari va metodikalar, matematikani amaliyotga bogʻlash, tajriba asosida oʻqitish, differensatsiyalashgan taʼlim, raqamli texnologiyalarni qoʻllash haqida soʻz yuritilgan.
Faktor-faktor yang Mempengaruhi Keputusan Pembelian pada Café Kokoro
Authors: Gustina Ihdina , Lazuardi Dedy , Wahyuni Putri , Rinaldi Muammar
Published: February 2025

Latar belakang: Cafe telah menjadi pusat pertemuan sosial dan telah menjadi integral dari budaya perkotaan modern di seluruh dunia. Dalam persaingan yang semakin ketat di industri ini, penting bagi pemilik bisnis cafe untuk menciptakan pengalaman yang memuaskan bagi pelanggan mereka. Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh dari Desain Eksterior dan Cita Rasa Terhadap Keputusan Pembelian Pada Cafe Kokoro.
Metode penelitian: Metodologi penelitian yang digunakan adalah metode deskriptif kuantitatif, unit analisis dalam penelitian ini adalah Cafe Kokoro. Teknik penentuan jumlah sampel yang digunakan dalam penelitian ini menggunakan rumus Slovin dan berjumlah 150 responden. Metode penelitian yang digunakan yakni dengan teknik pengumpulan data melalui penelitian kepustakaan dan penelitian lapangan yang dilakukan secara sistematik berdasarkan tujuan penelitian. Metode analisis yang digunakan untuk memecahkan permasalahan dan membuktikan hipotesis adalah dengan analisis deskriptif, analisis regresi. Analisis ini mencakup validitas dan reliabilitas, uji asumsi klasik, analisis regresi berganda, pengujian hipotesis melalui uji t dan F, dan uji koefisien determinasi (R2).
Hasil penelitian: Hasil dari uji t menunjukkan bahwa variabel Desain Eksterior 16,076 > ttabel 1,655 dan variabel Cita Rasa tidak berpengaruh dan signifikan terhadap Keputusan Pembelian Pada Cafe Kokoro dimana thitung 2,644 > ttabel 1,655. Hasil dari uji F menunjukkan bahwa Fhitung 156,293 > Ftabel 2,34 yang berarti variabel bebas yaitu Desain Eksterior dan Cita Rasa secara serempak berpengaruh terhadap variabel terikat yaitu Keputusan Pembelian pada Cafe Kokoro. Hasil uji koefisien determinasi (R2) menunjukkan bahwa 68% variabel Keputusan Pembelian pada Cafe Kokoro dipengaruhi oleh variabel Desain Eksterior dan Cita Rasa, sedangkan sisanya sebesar 32% dijelaskan oleh pengaruh faktor lain
Kesimpulan: Cafe Kokoro diharapkan dapat mempertahankan ruang eksterior yang luas agar pelanggan dapat bergerak leluasa demi kenyamanan pelanggan seperti mengatur jarak antar meja serta menggunakan furnitur berbahan alami untuk mendukung konsep Jepang sehingga pelanggan tetap memilih cafe Kokoro sebagai tempat pilihan utama berkumpul
UMA ANÁLISE DAS ESTRATÉGIAS OPERACIONAIS DA TROPA DE CHOQUE NO CONTROLE DE MULTIDÕES
Authors: Cemim Lucas , Nicola Neto Angelo
Published: February 2025

A gestão de multidões é um dos principais desafios da segurança pública, exigindo planejamento estratégico e preparo especializado das forças policiais para conter e dispersar grandes grupos sem comprometer a ordem e a segurança dos envolvidos. Neste cenário, a Tropa de Choque desempenha um papel essencial, adotando táticas que variam de ações preventivas a intervenções diretas, sempre buscando minimizar danos e restabelecer a ordem pública, retomando o controle da situação. Um dos fatores críticos nesse processo é a presença policial, que pode tanto dissuadir distúrbios quanto, em algumas situações, intensificar a tensão, dependendo da postura adotada e da forma como a tropa é posicionada no ambiente operacional. Este artigo explora as estratégias utilizadas pela Tropa de Choque, passando pelas diretrizes que norteiam o uso da força na Polícia Militar do Paraná, bem como o Manual de Operações em Controle de Multidões da Polícia Militar do Paraná. Além disso, são discutidas estratégias para minimizar conflitos e aprimorar a gestão de multidões, incluindo a mediação com lideranças, o uso seletivo da força e o posicionamento tático da tropa. Por fim, o artigo estabelece paralelos entre o uso seletivo ou diferenciado da força e a prioridade de emprego dos meios, conceitos utilizados, respectivamente, pelo policial militar no atendimento de ocorrências do dia a dia e pela Tropa de Choque em qualquer atuação de choque. A correta aplicação dessas estratégias operacionais permite a condução de operações seguras, protegendo tanto a integridade dos policiais quanto dos demais envolvidos.
Parents Assessment of Physician’s Mindful Practice
Authors: Bandi Viswanath , Dey Subrato Kumar , ORS Rao
Published: February 2025

This study aims to assess parental perceptions of physician mindfulness in their daily practice in the Indian context. After conducting an in-depth analysis of the existing publications, literature, physicians' mindfulness was assessed by administering the MAAS questionnaire, and parental perceptions were evaluated using the 21-item general communication subscale of the Personal Processes of Care Instrument. The MAAS was selected for its extensive use and validated efficacy in measuring mindfulness, particularly on moment-to-moment awareness of self-related experiences. This study involved 40 paediatricians and 40 parents, sampled conveniently, to assess internal consistency, covariate analysis, and descriptive statistics. Mindfulness was analysed via chi-square tests, while parental perceptions were examined through t-tests; both executed using Microsoft Excel 2011. Our analysis revealed that paediatricians, regardless of age or gender, demonstrated mindfulness. From the parents' perspective, there are significant areas for improvement, particularly in the physicians' explanations of diagnosis, medications, and responsiveness to parents' concerns. Additionally, addressing disrespectful behaviour by clinic assistants toward the parents emerged as a primary concern, highlighting the need for efforts toward improvement. Our research underscores the critical importance of mindfulness in paediatric practice and identifies key areas for improvement to enhance trust in physician-patient-centred disease management. It scrutinized the effects of physicians’ mindfulness on parental satisfaction during their child's medical condition consultations. The findings have further deepened our comprehension of mindfulness’s pivotal role and impact on well-being, ultimately seeking to expedite the healing process among children while nurturing positive engagements with physicians and clinic staff.
Bibliometric Exploration of Aeroponics and Sustainability Literature: Trends, Patterns, and Future Directions (1986-2023)
Authors: Sreejith B  , Harikumar Yedhu , Muthumeenakshi M  , Maneesh B
Published: February 2025

This work aims to provide a bibliometric and systematic overview of the progress of aeroponics research over the past thirty years. The study examined the publication pattern, productive authors, journals, and significant research topics throughout this period. The analysis reveals a consistent upward trajectory in the publishing trend of aeroponics in recent years. Recent years have seen a significant surge in academic publications on aeroponics in emerging nations like India, due to a range of contributing factors. The United States and China are in the forefront of citations, indicating their significant academic influence and substantial impact on the worldwide research environment. Primary areas of study include hydroponics, aeroponics, and potato growing, predominantly conducted in India, China, and the United States of America. Analysis of the systematic review revealed that Aeroponics can make a substantial contribution to sustainability. The application of aeroponics in sustainable agriculture holds promise, but there exist notable scientific shortcomings that must be addressed to optimise its implementation. These include assessments of long-term sustainability, analyses of energy use, investigations on scalability, evaluations of impacts on biodiversity, and studies on customer acceptance. Therefore, by giving priority to these areas, researchers can provide significant contributions to the progress of aeroponic systems that demonstrate not only exceptional efficiency and productivity, but also outstanding environmental sustainability and broad social acceptance. It is imperative to address the research gap in the area of sustainable food production among global challenges; it is inevitable to tackle the potential of aeroponics in agriculture.
Review on Vishajanya Janapadodwamsa Vyadhi w.s.r. to Environmental Toxicity
Authors: pujar Bhavani , Budihal Shivakumar
Published: February 2025

Environmental toxicology is a multidisciplinary domain of science, which occupies  an important niche, overlapping the field of toxicology. It focuses on humans and  other living beings and therefore plays an important role in addressing public health  challenges. With increasing numbers of environmental problems, there is a need  for immediate health solutions. Environmental toxicity and its health hazards are  not a new global issue; it has been in practice for 5,000 years. In olden days, kings,  when they entered enemy kingdoms along with the military, faced the threat of  being poisoned by entities like air, water, land, grass, and cattle feed. In present days,  because of human activities, industries, pesticides, chemicals, and other unhealthy  behaviors, the environment is getting poisoned and affecting the health of not only  human beings but also the other living creatures of the earth and aquatic ecosystems.  The present COVID-19 crisis is also a kind of environmental toxicity affecting the  whole world. This paper is an attempt to review the health problems and methods of  purification of such environmental particulates explained in classical texts and discuss  the adaptation of these methods for challenging problems related to environmental  toxicity in the present era.
Policy Development Framework for Operations Management During Crises: A Multiple Case Study of Nueva Ecija Cooperatives Amid the COVID-19 Pandemic
Authors: Dalde James Michael Alcaide
Published: February 2025

The COVID-19 pandemic presented unprecedented challenges to businesses worldwide, including cooperatives in Nueva Ecija, Philippines. These organizations faced unique trials due to their distinct structure and operations. This study aims to understand the crisis management strategies employed by these cooperatives during the pandemic. Utilizing Mitroff's (1994) five stages of crisis, resilience theory, and stakeholder theory, the research provides a comprehensive view of how cooperatives navigated each stage of the crisis.
Data analysis reveals that these cooperatives not only survived but also implemented multifaceted strategies to thrive amidst the challenges. Significant findings include their initial reactions, emergency planning, mitigation efforts, resumption of operations, and resilience building. The study underscores the importance of resilience and stakeholder engagement in effective crisis management, contributing to the academic discourse on cooperative management in crisis scenarios and offering practical guidance for cooperative leaders and policymakers.
The study concludes that crisis management of cooperatives in Nueva Ecija was aligned with stakeholder theory, resilience theory, and Mitroff’s five stages of crisis management. Initially unprepared, they quickly adapted by implementing emergency planning, digital communication, safety protocols, workforce management, and financial support. As operations cautiously resumed, they balanced economic recovery with health concerns. This research highlights that the cooperatives in Nueva Ecija effectively navigated the COVID-19 crisis, adhering to crisis management principles and providing valuable insights for similar organizations in managing future crises.
FREQUENCY, RISK FACTORS AND OUTCOMES ASSOCIATED WITH DIARRHEA IN CHILDREN UNDER AGE OF 2 YEARS AT KHYBER TEACHING HOSPITAL PESHAWAR; A CROSS-SECTIONAL STUDY
Authors: Hussan Jehan , Anjum Jehan , Ali Shahid , Israr Rabia , Khan Shehla , Gul Huma , Haq Raza Ul
Published: February 2025

Background:Toassessthefrequency ofdiarrheainchildrenunderthe ageof2yearsinthe regionofPeshawar and to determine its risk factors and outcomes.Materials & Methods:A cross sectionaldescriptive study was conducted in pediatrics wards andOPD in Khyber Teaching Hospital Peshawar from 1stMay 2021 to 31stAugust 2021 with a samplesizeof245children. The Information wascollectedthroughquestionnairedistributionandbyverballyaskingthemothersquestionsregardingdiarrhea.Foranalysis,weusedtheSPSSsoftwareversion20.Results:Thefrequencyofdiarrheainchildrenunder2yearsofagewasfoundtobe56.7% (139).Themajorrisk factors associated with diarrhea were the mother’s poor educational status(31.4%), children’s exposure to the sanitation system of the house (11.2%),incompletevaccinationstatus(16.73%),poorhandhygiene of mothers (8.59%), lack of using boiled water (9.5%)and residency in rural areas (8.24%). Out of 139 children who suffered from diarrhea 61.9% hadsunkeneyes,58.3%haddryskin,75.5%had lethargy,71.9%hadweightlossandonly10.1%hadlossofconsciousness.Conclusion:The frequency of diarrheawas very high in Peshawarand the major risk factors were lack of mother’s education, lack of use of boiled water, poor hand washing practice by mothers,incompletevaccinationstatusand residency in the rural area.Keywords: Diarrhea, Outcome, Prevalence, Risk Factors.
DENGUE HEMORRHAGIC FEVER
Authors: Jamil Zunaira , Farooq Umair , Kazmi Sadaf
Published: February 2025

Denguefeverisanairborneviralinfectiontransmitted bytheAedes mosquito with variouspresentations,froma simple flu-like illness to hemorrhagic manifestations.Hemorrhagic complications can vary from simple rashes to GIT bleeding, hematuria,andseverebleedsint h e brain.Hereisacaseof24yearsoldUmerAyubwithdenguefeveralongwith its hemorrhagic manifestations anddecompensated shock state who was intubated andputona ventilator, given16bloodtransfusions,butlaterhislabsimproved,he wasextubatedandrecovered well from a condition which has mortality rate above 95%.Key Words:DengueFever, Infection,LiverFailure
VITAMINDANDMALEFERTILITY
Authors: Qureshi Hamid Javaid , Tabbsum Maimona
Published: February 2025

Abstract:ExperimentalandobservationalresearchfoundthatmaleswithvitaminDdeficiencywerelikelytohavetestosteronedeficiencyorbeatincreasedriskforit.SemenqualitywasalsoshowntobeaffectedbylowvitaminDlevels,anditwasthemostconsistentfinding.IthasbeendemonstratedthatvitaminDdirectlyaffectsspermatozoaandhasabeneficialrelationshipwithspermmotility.BydescribingexperimentalandclinicalinvestigationsinanimalsandhumansaddressingthelinkbetweentestisfunctionandvitaminD,thecurrentreviewsummarizescurrentinformationontheroleofvitaminDinmalefertility.Keywords:VitaminD,Semenquality,Spermatozoa,Malefertility
PREVALENCE OF SOCIAL MEDIA WEBSITES USEDBYMEDICAL STUDENTS
Authors: Khalid Sumbal , Aslam Muhammad Sohail , Muzzamil Zunaira , Ahmar Fatima , Javaid Ayesha , Shafique Sara , Qureshi Aleem Ullah
Published: February 2025

Background:Social media use is becoming an addiction amongmedical students. This overuse of social media is leading to academic and mental instability in medical students. This study aimed to find out the prevalence of different social media website usage in medical studentsMaterial and Methods:This cross-sectionalstudy was conductedonMBBS students inthe third, fourth,and fifth years. 230 Questionnaires, containing 10 questions each, were distributed among the students at Farooq Hospital, Westwood, Lahore. 195 students filled out the questionnairesto participatingin the study. SPSS version 20 has been used for data analysis.Results: Among 195 students, 99.5 % used Snapchat, 96.9 % used WhatsApp, 96.4 % used Facebook, 95.3 % used Instagram,and 76.9 % used Tiktok.Conclusion: The majorityof medical students use different social media websites. Snapchat is appeared to be the most popular website among them. Most students spend less than 1 hour on social media per day. Key Words: Social Media, Medical Students,Questionnaires
PHYSIOLOGICAL EFFECTS OF MUSIC INHUMANBEINGS
Authors: Aslam Muhammad Sohail , Javaid Sidhu Muhammad Jabran
Published: February 2025

Music and ancient art arebeing used as a mode of entertainment. There isevidenceof its effectiveness as a therapy fordifferent diseases.Listening to rock music (440 Hz) results inincreased cortisol levels appetite, blood glucose, lipids and body weight. Whereaslistening to classical music (432 Hz) leads to a significant lowering of cortisol level due to its soothing effect. It also decreases blood glucose, lipids, appetite,and body weight.Classical music exposure helps to control anxiety.Conclusion:Listening to classical music helpsto relieve anxiety and reduces blood glucose, lipids,and body weight.Key Words:Music, Human body, Anxiety
SHIFTOF TRADITIONAL CURRICULUM TOINTEGRATED CURRICULUM: A DRASTIC STEP BY UNIVERSITY OF HEALTH SCIENCES (UHS), LAHORE
Authors: Ajmal Anum , Manzoor Iram
Published: February 2025

SHIFTOF TRADITIONAL CURRICULUM TOINTEGRATED CURRICULUM: A DRASTIC STEP BY UNIVERSITY OF HEALTH SCIENCES (UHS), LAHORE
PREVALENCE OF PERCEIVED STRESS IN MEDICAL ANDDENTAL STUDENTS DURING THEIR PROFESSIONAL STUDIES
Authors: Shoukat Mamoona , Ahmad Nadia , Ghafoor Ammara , Ahmad Fariha , Ejaz Shamaila
Published: February 2025

Background:Stress is a common condition among students of all professional studies which not only adversely affects their mental and physical health but also affects their performance during studies. The current study is performed to assess the impact of daily routine stress on their education.Material and Methods:300 medical and dental students from first to final year between the age group 18-25 years were selected and interviewed through an online perceived stress scale (PSS) questionnaire.Results:In our study, 8.6% (26 out of 300) of medical and dental students have low-stress levels, 61% (185 out of 300) have moderate stress levels and 29% (89 out of 300) showed high perceived stress levels.Conclusion:Medical and Dental students underwent moderate to high stress during their professional studies. Therefore, specific modifications are required in the professional curriculum so that a strong and healthy environment is provided to the students to reduce their stress levels. Multiple awareness and counselingsessions should be held throughout their course work that would help the students to cope with various challenges.KeyWords:Medical education, Curriculum, Awareness, Counseling
TO DETERMINE THE FREQUENCY OF CLOSTRIDIUM DIFFICILE INFECTION IN ANTIBIOTIC ASSOCIATED DIARRHEA
Authors: Abou Bakr Attique , Aslam Naeem , Ghias Mamoona , Mehfooz Imran
Published: February 2025

Background: Antibiotic associated diarrhea (AAD) is characterized by loose, watery stools, three or more times a day after intake of antibiotics.It is important to exclude all other possible causes of diarrhea before labeling it AAD. To determine the frequency of clostridium difficile infection in antibiotic associated diarrhea. Material and Methods: It was a cross sectional studydone in department of Gastroenterology, outpatient clinic,and ward, AIMC/ Jinnah Hospital, Lahorefrom 23 May 2019 to 23 November 2020. 234 patients fulfilling the selection criteria were enrolled in the study from the outpatient department and ward of Gastroenterology, Jinnah Hospital Lahore. Informed verbal consent was obtained and patients were subjected to focused history and physical examination as well as their demographic details wererecorded. Antibioticstaken by the patient were documented. The antibiotic was withdrawn and the patient was treated per hospital protocol. A stool culture was sent for all patientsto see CDI. The patient was labeled as CDI positive if stool culture is positive. All this information was recorded on a predesigned annexure.Results:Out of 234 cases of antibiotic induced diarrhea;the Mean Age was 55 ±13 years (minimum was 27 and maximum was 66 years) 56% of cases were male and 44% cases were female, 28.6% of cases had age ˂50 years and 71.4% cases had age ≥ 50 years, 54.7% cases used Beta-Lactam antibiotics and 45.3% cases used non-Beta-Lactam antibiotics, 68.4% cases had Bristol grade 6 and 31.6% cases had Bristol grade 7. Out of 234 cases of antibiotic associated diarrhea; 43.6% cases had CD infection and 56.4% cases had No CD infection. Stratification 0f CDI was done with regards to age groups, Gender, type of antibiotic used and Bristol grade; p-value was found to be 0.35, 0.41, 0.4 and 0.03 respectively.Conclusion: The majorityof patients withantibiotic induced diarrhea were male, had older age, used Beta-lactam antibiotics, had Bristol grade 6 and had a non-CD infection. Regarding CD infection; it was more common in older age, female gender and Beta-lactam antibiotic users; but associations were not significant. However,CD infection was more common in antibiotic induced diarrhea of Bristol grade 7 and the association was significant. KeyWords:Antibiotic,Diarrhea, Clostridium,Infection
MONKEY POX: A GLOBAL HEALTH HAZARD
Authors: Khan Momal , Liaqat Noor-ul-Ain
Published: February 2025

MONKEY POX: A GLOBAL HEALTH HAZARD
COMPARISON OF THE EFFICACY OF GLASS IONOMER AND RESIN BASED SEALANTS IN PERMANENT 1ST MOLARS IN 7-12 YEARS OLD CHILDREN
Authors: Manzoor Syeda  Afshan , Nazir Amara , Ahmad Rana Sadiq Amin , Asghar Faisal , Iqbal Humaira , Kashif Muhammad
Published: February 2025

Background:The present investigation sought to comparethe retention rates of glass ionomer and resin-based sealants in the permanent first molars of children aged seven to twelve years old. Material and Methods:A total of 112 participants were recruited and randomly allocated to either Group A (glass ionomer sealants) or Group B (resin-based sealants), with retention rates for the sealants assessed after one year.Results:The findings demonstrated that glass ionomer sealants' retention rate was significantly lower than resin-based sealants' (p< 0.05). Glass ionomer sealants had a retention rate of 57.1% compared to 81.3% for resin-based sealants. Conclusion:These results imply that resin-based sealants might be more successful in protecting the permanent first molars of kids between the ages of 7 and 12 against dental caries. This information can be useful to dental practitioners and policymakers in making decisions aboutthe optimal material for pi and fissuresealant application in this population.KeyWords: Dental caries,Molar, Population
RESTLESSLEGSSYNDROME:DIFFERENCEINQUALITYOF LIFEPARAMETERSBETWEENHEMODIALYSISPATIENTSWITHANDWITHOUTRESTLESSLEGS SYNDROME
Authors: Pervez Maira , Haq Ehtisham ul , Jamal Muhammad Nauman , Saeed Sameen , Arif Sana
Published: February 2025

Background:The majorityofabnormalmotionsthathappenduringsleepofteninvolvethemovementoflegs,the mostprevalentofwhichisRestlessLegsSyndrome(hereinafterreferredtoas“RLS”),also known as“Willis Ekbom Disease”. Hemodialysis therapy causes a variety of side effects inindividualswithchronicrenaldisease,notably RestlessLegsSyndrome,whichcanbequitedistressingforthispatientpopulation.Thisstudyseekstoascertaintheincidenceofrestlesslegssyndromeamongstpeoplewithchronicrenaldiseasereceiving hemodialysisin Lahorehealth facilities.Materialandmethods:Anon-probabilityconveniencesample of70patientswithchronickidneydiseasereceiving hemodialysis was takenin an observational (cross-sectional) research at the Shaikh ZayedNational Institute of Kidney Diseases and the Jinnah Hospital in Lahore. Using the widely acceptedIRLSSG diagnostic criteria, restless legs syndrome was identified in respondents who answered yes to allquestionnaire items. The WHOQOL BREF (World Health Organization QoL Brief Version) assessmentwasused to examineone's quality oflife.Results: Participants' mean ages ranged from 54.97±9.54 years. 46 (65.7%) of the 70 participants weremen, and 24 (34.3%) were women. RLS was observed to be more common in men (62.2%) than that inwomen(37.8%).Restless legs syndrome was found to be hurtingthe quality of life in hemodialysis patients, especially in physicaland psychological domains.Conclusion:Thequalityoflifeof hemodialysis patientsisnegativelyaffectedbyRLS,withconsiderableinfluence on theirpsychological and physical well-being. As a consequence, medical practitioners ought to doeverythingpossibleto recognizeand treatRLSsymptomsinthis demographicatrisk.KeyWords:Restlesslegssyndrome,hemodialysis,qualityoflife
"TREATMENT SUCCESS OF SOFOSBUVIR AND DACLATSVIR WITH OR WITHOUT RIBAVIRIN IN PATIENTS OFHEPATITIS C VIRUS"
Authors: Ahmad Ather Ch Adnan , Nawaz Mariyam , Bashir Sulehria Sohail , Chaudary Saadia , Mehmood Zara , Rehman Maria
Published: February 2025

Background:To compare the frequency of responders achieving SVR12 after taking sofosbuvir and daclatasvir with vs without ribavirin.Material and Methods:Total 180 patients meeting inclusion criteria were enrolled in the studyfromDepartment of Medicine, Government Teaching Hospital Shahdara, Lahore.This randomized controlled trial was conducted fromMarch 25, 2021,to September 24, 2021.Treatment naive cases were given tablet sofosbuvir & daclatasvir for 12 weeks. Treatment-experienced and naive with cirrhosis were given ribavirin based on their body weight along with sofosbuvir and daclatasvir for 12 weeks. After 3 months of treatment, patients were called for follow up at 12thweek post-treatment for HCV RNA PCR to see if patient has achieved SVR12 or not. Statistical analysis was performed using SPSS v25.0. Frequency of responders was compared using the Chi-square test. P-value less than or equal to 0.05 was considered statistically significant. Results: In group-A, 54(60.0%) patients were males and 36(40%) patients were females. In group-B, 52(57.8%) patients were males and 38(42.2%) were females. The mean age in patients of group-A was 45.69±12.481 years while that was 44.99±14.590 years in group-B. In group-A (Sofosbuvir and daclatasvir with ribavirin), 81(90.0%) patients had a response rate and in groupB (Sofosbuvir and daclatasvir), 65(72.2%) patients had a response rate with p-value (p=0.002). Conclusion:It was concluded that sofosbuvir & daclatasvir with ribavirin was found more efficacious than sofosbuvir & daclatasvir alone in achieving SVR 12 in patients of chronic hepatitis C infection, so it will help in delaying disease process and improving quality of life,especially in the developing world.KeyWords:Sofosbuvir, Daclatasvir, Ribavirin, Hepatitis C
LEVEL OF JOB SATISFACTION IN HEALTHCARE PROFESSIONALS WORKING AT KHYBER TEACHING HOSPITAL PESHAWAR, PAKISTAN
Authors: Khan Hayat Muhammad , Hussan Jehan , Ahmed Afridi Aibad , Khan Nida , Wazir Zakia , Akmal Maheen
Published: February 2025

Background: An effectively working institution dependson its skilled, motivated and well supported employees which aredetermined by said workers'working conditions, circumstances and environment.This is especially true for doctors and nurses whose workperformance is closely linked to patient safety and quality patient care. Job satisfaction is defined by how employees feel about different aspects of their jobs. Different factors are involved in job satisfaction in different settings.Material and Methods: It was a cross sectional study conducted in Khyber Teaching Hospital Peshawarinvolving health care Personnel'sselected throughNon probability quotasampling technique. Total 335 health care Personnel'swere interviewed using structured questionnaire. Data was analyzed using SPSS version 20.Results:Overall, 73.6% of participants were satisfied with the different factors of their working conditions. The results of the study revealed the major factors were Support from senior colleague (83.3%),Amount of hours health care workerswork (82.7%), salary and vacation time (82.4%), On Job Training (76.1%). Other factors were presence of feedback system, involvement in decision making, good use of skills, promotion and job security.Conclusion: Theoverall satisfaction level was high. Support from seniors, Salary and vacation time, Promotion in job and colleagues support is important motivators for job satisfaction.Key Words: Job satisfaction, Health personnel, Working environment
RETRO-PERITONEAL HEMORRHAGE POST CORONARY ANGIOGRAPHY: A CASE REPORT
Authors: Ahmad Muhammad  Awais , Farooq Omair , Kazmi Syeda  Sadaf , Abbasi Muhammad  Afzal , Fatima Shoaib Shameen
Published: February 2025

Background: Retro-peritoneal hemorrhage is an infrequent complication after percutaneous coronary angiography. It occurs when the transfemoral approach is used. Without early diagnosis and prompt treatment,it can lead to fetalconsequences.Case presentation: We report a case of a 44-year-old male who developed retro-peritoneal hemorrhage post coronary angiography and was successfully managed conservatively and was discharged.Conclusion: Retro-peritoneal hemorrhage should be kept as a differential in patients who show signs of hypovolemic shock after coronary angiography. Non-contrast computed tomography (CT) scan of the abdomen and pelvis should be done for its diagnosis.
EFFECTIVENESS OF AUTOLOGOUS RECTUS SHEATH SLING ABDOMINAL PROCEDURE FOR UTERO-VAGINAL PROLAPSE
Authors: Abid Shazia , Ashraf Adila
Published: February 2025

Background:Uterovaginal prolapse is one of the most common presentations among women attending gynecological OPD. Various conservative procedures have been reported in the past, each with advantages and disadvantages.The objective of this study is to assess the effectiveness of autologous rectus sheath sling abdominal procedure for uterovaginal prolapsedMaterial and Methods:The current study was a retrospective observational study carried out at the gynecology department, Indus Hospital Lahore. Consecutive samplingwas done to includeall patients who had this surgery during 2018-2022. After the surgery, follow up was started from day 10th of surgery, the second follow up was at 1 month after surgery and the last was after 6 months to assess complicationsof the procedure and effectiveness of procedure. Data wereanalyzed using SPSS 24.Results:In the current study, a total 30 patients were enrolled. The mean age of the patients was 30(4.12) years. Based on the degree of prolapse, the first degree of prolapse was observed in 18 (60%) patients while the second degree of prolapse was observed in 12 (40%) patients. The success rate was observed in 100% of patients (n=30)immediatelypost-operativelyand 2 patients got pregnant after the surgery and delivered normally in the same hospital without any difficulty and with the maintenance of the effectiveness of surgery.Two patients developed first degree uterovaginal prolapse after surgery andwere initially having 2nddegree prolapse.Severe blood loss and visceral organ injury werenot observed in any enrolled patients while post operative fever and recurrence wereobserved in 2 (6.67%) and 2(6.67%) patients respectively.Conclusion:The use of an autologous rectus sheath as a sling in uterine conservationsurgery for uterovaginal prolapse is an efficient, safe and cost-efficient approach, especially for younger women needing uterine conservation surgery.Key Words:Surgery, Pregnant, Prolapse
PROPHYLACTIC EFFECT OF CITRULLUS LANATUS &CURCURBITA PEPO SEEDS EXTRACT VERSUS DUTASTERIDE ON HORMONAL PARAMETERS IN BENIGN PROSTATIC HYPERPLASIARATS
Authors: Fatima Aslam Bisma , Shahzad Alam Saadia , Iftikhar Piracha Mariyam , Zulfiqar Tehreem , Jabbar Sadaf , Mansoor Maryam
Published: February 2025

Background:Benign Prostatic Hyperplasia (BPH) is the most common benign neoplasm and is a possible cause of urinary obstructionin elderly males.The current study evaluated theProphylactic effect of Citrullus lanatus and Curcurbita Pepo seeds extract versus Dutasteride on hormonal parameters in BPH rats.Material and Methods:Over the 29-dayresearch period, 42 healthy adult male albino rats were divided into 6 groups of 7 animals, except group 1,each received daily testosterone 3mg/kg s.c and medications as per designated groups for initial 14 days for BPH induction & from 15-29 days for maintenance. Group 1 was normal healthy control & 2 was disease control. Other groups were group 3 (3mg/kg Testosterone s.c + 0.5mg/kg dutasteride p.o), group 4 (3mg/kg Testosterone + 2g/kg Methanolic Extract of Citrullus Lanatus Seeds, MECLSp.o), group 5 (3mg/kg Testosterone s.c + 5g/kg Petroleum Ether Extract of Curcurbuta Pepo Seeds, PECPSp.o) & group 6 (3mg/kg Testosterone s.c + 1g/kg MECLS p. o+2.5g/kg PECPS p.o). Their blood sampleswere taken on d0, 14 and 29daysfortestosterone and PSAestimationby ELISA technique.Results:Prophylactic combination of 1g/kg Methanolic Extract of Citrullus Lanatus Seeds & 2.5g/kg Petroleum Ether Extract of Curcurbuta Pepo Seeds produced significant improvement in serum PSA& testosteroneequivalent to Dutasteride.The individual herbs 2g/kg MECLS & 5 g/kg PECPS produced gradual similar improvement over a prolonged duration (29 days) withoutany side effects. Conclusions: This suggestsMECLS+PECPS to be equivalently effective & safe as Dutasteride in the prophylaxis of the BPH murine model.KeyWords: Benign prostatic hyperplasia, urine output, Dutasteride, serum PSA and testosterone.
Assessment of YouTube videos on ultrasound-guided lower extremity peripheral nerve blocks
Authors: Göger Esra
Published: February 2025

Aims: Numerous YouTube videos on lower extremity nerve blocks, frequently utilized for analgesia in anesthesia practice, are available to the public. To prevent the spread of incorrect or incomplete information and reduce information pollution, it is essential to review these videos critically. Accordingly, this study assessed the educational content and preparation quality of videos on YouTube about lower extremity nerve block. Methods: Two structured surveys assessed ten different types of lower extremity nerve block educational videos on YouTube. Each survey comprises 14 questions, each scored on a scale from 0 to 5. This results in a total possible score between 0 and 70 for each video per survey. Results: A statistically significant and strong correlation was observed between the video preparation quality score and the video educational quality score (p<0.001). Additionally, there was a statistically significant positive association between the number of video likes and both the video preparation quality score and the video educational quality score (p<0.05 for each). Conclusion: While YouTube provides a range of medical training videos, concerns persist regarding the reliability of this content. Consequently, obtaining medical information from reputable sources such as peer-reviewed academic journals or publications issued by official medical organizations offers a more accurate and dependable foundation for research.
Letter: Evaluation of the Frequency of Hepatitis B Virus Reactivation and the Importance of Hepatitis B Prophylaxis in Hematology Patients Receiving Immunosuppressive Therapy: A Single-Center Study
Authors: Başpınar Batuhan , Güven İbrahim Ethem
Published: February 2025

Letter to the Editor
ANALISIS SENTIMEN MASYARAKAT INDONESIA PADA PLATFROM X TERHADAP ISU FUFUFAFA MENGGUNAKAN BIDIRECTIONAL ENCODER REPRESENTATIONS FROM TRANSFORMERS
Authors: Amelia Amanda , Yusuf Ridwan
Published: February 2025

Media sosial, khususnya Twitter, telah menjadi platform utama untuk menyampaikan opini, berbagi informasi, dan mempengaruhi opini publik. Fenomena “Fufufafa” yang menjadi trending di Twitter mencerminkan tingginya perhatian masyarakat terhadap isu-isu yang terkait dengan ujaran kebencian dan perilaku toxic di dunia maya. Dengan 24,85 juta pengguna aktif di Indonesia pada tahun 2023, Twitter menjadi tempat yang signifikan untuk menganalisis sentimen masyarakat. Penelitian ini bertujuan untuk memahami persepsi publik terkait isu tersebut melalui analisis sentimen menggunakan metode VADER dan BERT. Hasil analisis menunjukkan distribusi sentimen dengan 409 teks positif, 207 teks negatif, dan 575 teks netral. Metode BERT dengan kombinasi batch size 8 dan 5 epochs memberikan hasil terbaik, dengan akurasi tinggi serta evaluasi metrik yang seimbang. Temuan ini mengindikasikan pentingnya parameter pelatihan yang tepat untuk meningkatkan efektivitas model analisis sentimen. Penelitian ini memberikan wawasan opini masyarakat di media sosial, yang dapat dimanfaatkan untuk memahami isu-isu sosial dan membangun strategi komunikasi yang lebih baik di dunia digital.
ANALISIS DAN DESAIN SISTEM INFORMASI MANAJEMEN RESTORAN BERBASIS WEB STUDI KASUS PECEL KAWI HJ.MUSILAH
Authors: Ismawan Puji , Cahyono Dwi
Published: February 2025

This study analyzes and designs a web-based restaurant management information system for Pecel Kawi Hj. Musilah. Qualitative methods develop an application displaying menu, pricing, best-sellers, payment receipts and customer data. The system analyzes frequently ordered menus and generates monthly reports. Results show the web-based system enhances service efficiency, customer satisfaction and management ease. The Waterfall model addresses manual ordering issues. This research contributes to developing effective restaurant management information systems. Additionally, the system aids employees in data management and improves service quality, increasing revenue and customer satisfaction.
ANALISIS USABILITY WEBSITE PROFILE SD NEGERI PENGGALANG 03 DENGAN METODE SYSTEM USABILITY SCALE
Authors: Yuliarestu Ade Fauzan , Sugiyanto Sigit , Supriyono Supriyono , Hamka Muhammad
Published: February 2025

Website SD Negeri Penggalang 03 adalah platform yang dirancang untuk mempermudah penyebaran informasi terkait profil dan kegiatan sekolah serta menjadi jembatan komunikasi antara Guru, Siswa, dan Wali Siswa. Namun, observasi langsung menunjukkan adanya permasalahan usability, seperti navigasi yang kurang intuitif, penamaan menu yang tidak konsisten, dan tampilan visual yang tidak seragam. Penelitian ini bertujuan mengevaluasi kegunaan website tersebut menggunakan metode System Usability Scale (SUS). Metode ini digunakan untuk mengidentifikasi masalah usability, memberikan gambaran kondisi awal kegunaan situs, serta menyusun rekomendasi perbaikan. Melibatkan Guru, Siswa, dan Wali Siswa sebagai responden, penelitian ini menggunakan kuesioner SUS 10 pernyataan untuk menilai aspek usability, seperti kemudahan penggunaan, konsistensi fitur, dan hambatan operasional. Skor rata-rata SUS sebesar 73.03 menunjukkan tingkat usability dalam kategori "Acceptable" dengan Grade Scale B- dan Adjective Rating "Good" yang menunjukkan sudah dapat diterima. Namun, terdapat temuan kelemahan yang perlu diperbaiki, seperti tampilan visual yang kurang konsisten dan elemen tata letak yang tidak rapi, sehingga memengaruhi aspek usability. Selain itu, meskipun mayoritas pengguna merasa website ini mudah digunakan, sebagian responden menilai negatif. Rekomendasi perbaikan meliputi penambahan navigasi responsif, panduan interaktif, evaluasi fitur, petunjuk visual, dan penyederhanaan antarmuka. Dengan perbaikan ini, diharapkan usability website menjadi lebih optimal dan mendukung tujuan penggunaannya secara efektif.
ANALISIS USABILITY SITUS WEB INFORMASI SD NEGERI 02 KURIPAN MENGGUNAKAN METODE WEBSITE USABILITY EVALUTION TOOL (WEBUSE)
Authors: Eksa Sendika Kurnia , Sugiyanto Sigit , Wibowo Feri , Hamka Muhammad
Published: February 2025

Penelitian ini bertujuan untuk mengetahui penyebab masalah kurangnya kenyamanan dan efisiensi pada aspek usability situs web SD Negeri 02 Kuripan, guna memberikan rekomendasi perbaikan yang dapat meningkatkan pengalaman pengguna. Fokus populasi penelitian ini mencakup tiga kelompok pengguna utama situs web, yaitu guru, siswa, dan wali murid, yang berjumlah 453 orang. Jumlah sampel yang digunakan sebanyak 82 orang dengan menerapkan teori sampel Slovin dan teknik Stratified Random Sampling. Analisis dilakukan menggunakan metode Website usability evaluation tool (WEBUSE), yang mempunyai empat aspek utama usability yakni Content, Organization, and Readability , User Interface Design, Navigation and Links, serta Performance and effectiveness. Hasil penelitian menunjukkan bahwa kategori Content, Organization, and Readability memiliki tingkat usability "Moderate" (skor 0,5), sehingga memerlukan perbaikan pada struktur konten, pagination responsif, dan pembaruan informasi. Kategori User Interface Design memperoleh skor "Good" (0,75) dengan rekomendasi penambahan ikon berwarna dan penyesuaian warna agar lebih menarik. Sementara itu, kategori Navigation and Links dan Performance and effectiveness mencapai skor "Excellent" (0,82), menunjukkan performa yang sangat baik tanpa memerlukan perbaikan lebih lanjut. Perbaikan yang direkomendasikan berfokus pada peningkatan kemudahan, kejelasan, dan efisiensi dalam proses penyampaian serta penerimaan informasi pada situs web SD Negeri 02 Kuripan.
PENERAPAN METODE K-MEANS CLUSTERING UNTUK PEMETAAN PERBAIKAN JALAN DI KOTA BOGOR
Authors: Wulandari Annisa , Irmayansyah  , Ningrum Leny Tritanto
Published: February 2025

Perbaikan jalan sangat penting untuk menjaga fungsinya dalam menunjang ekonomi dan aktivitas sosial. Perbaikan jalan yang terencana bukan hanya sebuah kebutuhan teknis, tetapi juga merupakan investasi untuk keselamatan, efisiensi, dan kesejahteraan masyarakat, Oleh karena itu penting bagi pemerintah dan instansi terkait untuk melakukan perencanaan yang matang dalam program perbaikan infrastruktur jalan. Adapun metode yang digunakan dalam mengelompokan data perbaikan jalan yaitu algoritma K-Means dengan hasil keluaran berupa tiga kluster dimana Klaster 1 merupakan klaster dengan tingkat perbaikan Tinggi, klaster 2 merupakan klaster dengan tingkat perbaikan Sedang, dan klaster 3 merupakan klaster dengan tingkat perbaikan Rendah dan sudah dilakukan uji validitas cluster menggunakan Silhouette Coefficient terhadap algoritma K-means yang diterapkan dengan nilai yang diperoleh sebesar 0,659 yang berarti cluster yang dibentuk termasuk kedalam kategori struktur baik .  Pada ptoyotype aplikasi yang dibangun telah dilakukan uji kelayakan oleh ahli sistem menggunakan metode white box dengan hasil persentase kelayakan sebesar 100% yang dapat dikategorikan ke dalam interpretasi sangat layak”, juga telah dilakukan juga uji kelayakan oleh pengguna menggunakan instrumen Post-Study System Usability Questionaire (PSSUQ) dengan hasil perolehan yakni nilai kepuasan secara keseluruhan sebesar 78,9%, yang artinya aplikasi ini layak digunakan.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS AUGMENTED REALITY PADA MATERI PENGENALAN BANGUN RUANG DI SD NEGERI 1 PURBALINGGA WETAN
Authors: Verdiatmoko Ardief Candra , Pinandita Tito
Published: February 2025

Perkembangan teknologi dalam bidang pendidikan telah menghadirkan berbagai inovasi signifikan, salah satunya adalah Augmented Reality (AR). Teknologi ini memungkinkan integrasi komponen digital ke dalam lingkungan nyata secara interaktif. Namun, keterbatasan media pembelajaran interaktif untuk menjelaskan konsep abstrak, seperti bangun ruang dalam matematika, masih menjadi tantangan bagi siswa sekolah dasar. Metode pembelajaran konvensional yang mengandalkan buku dan alat peraga statis sering kali tidak mampu meningkatkan pemahaman siswa secara optimal. Penelitian ini bertujuan untuk mengevaluasi efektivitas media pembelajaran berbasis AR dalam meningkatkan pemahaman siswa terhadap materi bangun ruang. Penelitian menggunakan pendekatan Research and Development (R&D) dengan model pengembangan ADDIE, yang mencakup tahapan Analisis, Desain, Pengembangan, Implementasi, dan Evaluasi. Subjek penelitian adalah siswa kelas 5 SD Negeri 1 Purbalingga Wetan. Hasil penelitian menunjukkan peningkatan rata-rata nilai pre-test sebesar 66,25 menjadi 83,5 pada post-test, dengan selisih 17,5 poin. Media pembelajaran berbasis AR memberikan pengalaman belajar interaktif dan manipulatif, sehingga mempermudah siswa dalam memahami hubungan antar elemen bangun ruang. Umpan balik dari siswa dan guru menunjukkan bahwa media AR tidak hanya meningkatkan motivasi dan minat belajar siswa, tetapi juga mempermudah guru dalam menyampaikan materi yang bersifat abstrak. Untuk pengembangan lebih lanjut, disarankan agar fitur interaktif pada aplikasi AR diperbanyak serta kompatibilitasnya ditingkatkan untuk memperluas aksesibilitas
DIREITOS E GARANTIAS FUNDAMENTAIS E A PROTEÇÃO AO PRINCÍPIO DA DIGNIDADE DA PESSOA HUMANA
Authors: Gass Eduardo Bohn , De Moraes Dilcionir , Feltraco Tiago Daniel , De Oliveira Fábio Ribeiro , Conegatto André Xouquel
Published: February 2025

This article analyzes the effectiveness of fundamental rights and guarantees in ensuring that citizens' rights are upheld. The general objective is to examine fundamental rights and guarantees, while the specific objectives include analyzing the characteristics of these norms and their historical evolution. The methodology applied was bibliographic research, using the hypothetical-deductive approach. The outlined concepts demonstrate that numerous historical revolutions have marked various societies in the pursuit of abandoning absolutist regimes and fighting for the minimum conditions necessary for citizens to live with dignity in society.