bluuebunny/crossref_metadata_2025 huggingface dataset:
A STUDY TO ASSESS LIFESTYLE CHANGES AND MENTAL HEALTH STATUS AMONG MEDICAL STUDENTS DURING COVID-19 - A CONCERN AND NEED FOR ACTION.
Authors: Rani B Savitha , S Gopinath , C Nair Greshma
Published: January 2024

Introduction: The covid-19 pandemic poses a worldwide danger, the scale of which is uncertain. In addition to the
associated infectious diseases,the harmful impacts include indirect effects such as an imbalanced diet that increases the
risk of weight gain or nutritional deficiencies, an increase in sedentary behavior, and impaired mental health.
Objective:To Assess the lifestyle-related behavior and mental health status of medical students and factors influencing
the same during the covid-19 pandemic.Methodology:This is a cross-sectional study conducted among the students of
a medical college in Tumkur.sociodemographic data,BMI and physical activity during covid,lifestyle-related behavior
scores,and Physical Health Questionnaire-9 were collected.Statistical analysis was done using Descriptive statistics like
proportion and Inferential statistics like the Chi-square test.A P-value less than 0.05 was taken as statistically significant.
Results: Sixty (49%) of the 124 students were male, and sixty-four (51%) were female.In comparison to pre-covid, the
BMI changed dramatically throughout covid (p<0.001). 40 percent of students who were normal weight before covid
became overweight.Only 20% of the individuals frequently engaged in exercise.Depression affected 41% of people.88
percent of those who engage in daily exercise reported not having depression(p<0.001). There was a significant
association between physical activity and depression. Conclusion: From the above results, we can conclude that the
Covid-19 Pandemic scenario resulted in an unhealthier lifestyle among medical students. To reduce the pandemic's
detrimental effects, regular Physical activity and following a Healthy lifestyle play an important role and also help to
overcome depression.
On Standardized Service Interfaces for the Interoperability of Tokenized Asset Networks
Authors: Hardjono Thomas , Lipton Alexander , Pentland Alex
Published: January 2024

Many businesses seeking new capabilities that blockchains may offer are deterred from fully embracing the technology due to fears of the classic ”vendor lock-in” and platform-capture into one specific blockchain. From an asset-centric perspective, most business applications seek certain desirable functional guarantees with regard to the state of the tokenized asset on the blockchain. These new capabilities must be accessible through standardized service interfaces. The emerging tokenized asset networks based on decentralized ledger technology must integrate seamlessly into existing financial IT systems through similar standard interfaces. As such, if blockchains are to be a foundational technology in the future Web3 Internet of Value, then several classes and types of standardized APIs must be specified, published, and widely deployed by the nascent tokenized asset industry. These standard APIs must provide business applications with a single uniform interface to the many and varied blockchains today, thereby reducing business IT costs and preventing platform-capture.
Ferrite Core Loss Prediction with Direct Data Interpolation Method
Authors: Tian Yidong , Zhang Cheng
Published: January 2024

This paper proposes a direct data interpolation method for predicting ferrite core loss in power electronics. The core idea is to accurately construct the B-H loop shape given arbitrary Hfield waveforms. Unlike conventional loss models like the Steinmetz equation and its variations, or recent neural network methods like MagNet that leverage periodic B-H waveforms and frequencies, this method employs a data segmentation and reconstruction process to fully exploit the distinctive features of the B-H loop under varying conditions. The source data is from Princeton University’s MagNet open-source datasets.
Formação ou (informação) de professores
Authors: De Sousa Mariana , Michelli de Castro Rosane , Aparecida de Lima Elieuza , Marques Tezza Leonardo
Published: January 2024

Neste artigo são apresentados resultados do trabalho de conclusão de curso de Pedagogia da Faculdade de Filosofia e Ciências – FFC – Universidade Estadual Paulista “Júlio de Mesquita Filho” – UNESP/Câmpus de Marília. Trata-se de resultados de estudo desenvolvido com o objetivo geral de identificar e compreender elementos históricos e socioculturais que influenciam o processo de formação de professores e professora, em dois países, no Brasil e em Coréia do Sul, com alguns aspectos históricos semelhantes e industrialização recente, porém, que tiveram desfechos específicos no campo educacional, sobretudo na formação de professores para o ensino do nível correspondente à Educação Básica Brasileira. Trata-se de resultados de pesquisa de abordagem histórica e bibliográfica, quanto às fontes. Como resultados finais, foram apresentadas algumas considerações sobre a história da formação de professores e professoras, a valorização do trabalho docente e os resultados que trazem em seus respectivos contextos.
Periodontal disease etiology and role of oxidative stress
Authors: Jabbar Dhamyaa
Published: January 2024

The term "periodontal disease" is used to describe an array of inflammatory conditions that can affect the periodontium. In response to the challenge given by the bacteria, the gingival and periodontal tissues undergo a complicated chain of events involving communication It is between the membranes of a vital nature located under the gums and the person's immune inflammatory reaction. When there is an imbalance between the oxidants and the antioxidants in the body, this is known as oxidative stress. Antioxidants are compounds that may either seek out and destroy oxidants or prevent them from forming in the first place. Some of the oxidants produced by-products of normal cellular metabolism include reactive oxygen species and reactive nitrogen species. These byproducts are known as reactive oxygen and reactive nitrogen species, respectively. The presence of reactive oxygen species (ROS) has been shown to be associated with periodontal disease in research.
Strategi Peningkatan Pendapatan Pajak Bumi dan Bangunan Perdesaan dan Perkotaan (PBB-P2) Oleh Badan Keuangan Daerah Kota Pontianak
Authors: Hanafi Imam , Sulaiman Sulaiman , Aziz Ahmad Robiul
Published: January 2024

Letak objek pajak PBB-P2 tersebar di seluruh wilayah Kota Pontianak, sehingga merupakan potensi yang besar untuk peningkatan PAD dari sektor pajak. Namun jumlah lembaran SPPT PBB-P2 yang dibayarkan selalu menurun setiap tahunnya, ini mengakibatkan jumlah lembaran SPPT PBB-P2 yang belum dibayarkan meningkat setiap tahunnya. Penerimaan realisasi PBB-P2 di tahun 2022 merupakan yang tertinggi sepanjang tahun, kendati demikian jumlah wajib pajak yang membayar PBB-P2 di tahun 2022 hanya sebesar 38% atau 87.238 lembar SPPT, ini menunjukkan masih ada potensi yang masih bisa digali untuk menambah PAD dari sektor PBB-P2. Tujuan penelitian ini untuk mengetahui strategi yang dilakukan Badan Keuangan Daerah Kota Pontianak dalam meningkatkan Pajak Bumi dan Bangunan Perdesaan dan Perkotaan (PBB-P2) tahun 2022, hambatan dari strategi yang dilakukan dalam meningkatkan pendapatan Pajak Bumi dan Bangunan Perdesaan dan Perkotaan (PBB-P2) tahun 2022, solusi yang dilakukan Badan Keuangan Daerah Kota Pontianak dalam mengatasi hambatan dalam meningkatkan pendapatan Pajak Bumi dan Bangunan Perdesaan dan Perkotaan (PBB-P2) tahun 2022. Jenis penelitian yang digunakan adalah metode kualitatif. Teknik pengumpulan data yang digunakan adalah teknik wawancara dan studi dokumentasi. Hasil penelitian ini menunjukkan bahwa Badan Keuangan Daerah Kota Pontianak melakukan strategi peningkatan pendapatan PBB-P2 dengan cara intensifikasi, ekstensifikasi serta strategi lain seperti penyesuaian NJOP, Kegiatan jemput pajak PBB-P2, Penghapusan denda administrasi, serta melakukan razia. Adapun hambatan yang dialami oleh BKD dalam peningkatan PBB-P2 yaitu terkait kesadaran masyarakat serta terkait data warisan dari pemerintah pusat ke pemerintah daerah yang belum valid. Untuk mengatasi hambatan ini BKD melakukan sosialisasi tentang PBB-P2 kepada wajib pajak serta melakukan cleansing/pemutakhiran data secara bertahap.
MINIMIZE NPK 16-16-16 FERTILIZER BY APPLICATION OF PINEAPPLE PEEL POC ON PURPLE EGGPLANT PLANT (Solanum melongena L)
Authors: Lase Kikie Swandi , Berliana Yunida , Kurniawan Dedi , Angkat Nina Unzila
Published: January 2024

Terong ungu (Solanum melongena L.) ialah sayuran yang banyak ditanam di Indonesia. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pupuk NPK 16-16-16 yang dikombinasikan dengan penggunaan POC kulit nanas terhadap pertumbuhan dan hasil tanaman terong ungu. Penelitian dilakukan di kebun masyarakat di Kecamatan Medan Helvetia, Sumatera Utara. Penelitian menggunakan dua faktor perlakuan dengan Rancangan Acak Kelompok (RAK) Faktorial. faktor satu yaitu dosis pupuk NPK 16-16-16 yang terdiri dari empat taraf: N0 (kontrol), N1 (10 gram/tanaman), N2 (20 gram/tanaman), dan N3 (30 gram/tanaman). Faktor dua POC kulit nanas terdiri empat taraf: P1 (50 ml POC + 950 ml air = 1 L/Plot), P2 (100 ml POC + 900 ml air = 1 L/Plot), P3 (150 ml POC + 850 ml air = 1 L/Plot), dan P4 (200 ml POC + 800 ml air = 1 L/Plot). Parameter yaitu tinggi tanaman (cm), jumlah cabang, usia saat panen (hari), berat buah per tanaman (gr), jumlah buah per tanaman, dan berat buah per plot. Hasil penelitian menunjukkan bahwa pupuk NPK 16-16-16 memberikan dampak positif pada tinggi tanaman, jumlah cabang, usia saat panen, berat buah per tanaman, jumlah buah per tanaman, dan berat buah per plot dosis terbaik 20 g/tanaman (N2) . Aplikasi POC kulit nanas juga berpengaruh pada tinggi tanaman pada umur 5 MST, jumlah cabang, berat buah per tanaman, jumlah buah per tanaman, dan berat buah per plot. Hasil terbaik dengan menggunakan kombinasi pemberian NPK 16-16-16 sebanyak 20 g/tanaman (N2) dan aplikasi POC kulit nanas sebanyak 150 ml POC + 850 ml air.
Potensi kemopreventif fraksi n-heksan biji kebiul (Caesalpinia bonduc (L) Roxb.) Bengkulu pada chorioallantoic membrane yang diinduksi bFGF
Authors: Hayati Risda , Nadia Nadia , Karini Amey Putri , Shavitry Ayyu , Romdani Ayu Nadiyah Permatasari , Wulandari Septi
Published: January 2024

Kanker merupakan pertumbuhan atau pembengkakan massa dari sel yang abnormal, tidak terkontrol, dan bersifat ganas. Adanya pembentukan pembuluh darah tersebut maka dibutuhkan antiangiogenesis karena tanpa suplai darah, sel kanker akan mati. Tanaman biji kebiul (Caesalpinia bonduc (L) Roxb.) mengandung metabolit sekunder sebagai antikanker. Riset ini dengan menggunakan metode eksperimental, yaitu pembuatan ekstrak dan fraksi N-Heksan, Uji Fitokimia, dan Uji Antiangiogenesis. Hasil rendemen biji kebiul 13,608%. Pada uji fitokimia fraksi n-heksan biji kebiul memberikan hasil positif untuk alkaloid, flavonoid, triterpenoid, dan tanin. Pada kelompok paper disc blank, paper disc dengan pelarut DMSO dan Paper disc yang diinduksi bFGF skor rata-rata 0 (tidak aktif). Fraksi N-Heksan degan konsentrasi 02 mg/ml paling aktif dan efek antiangiogenesisnya paling besar dan bagus dengan skor rata-rata 1,66 (Bagus), pada konsentrasi 0,1 mg/ml dengan skor rata-rata 1,33 (bagus) dan pada konsentrasi 0,05 mg/ml dengan skor rata-rata 0,83 (lemah). Pengamatan makroskopis menunjukkan bahwa ekstrak biji kebiul menghambat pertumbuhan pembuluh darah baru pada CAM embrio ayam yang diinduksi bFGF tergantung konsentrasi yang diberikan.
Efektivitas jelly buah bit terhadap kadar hemoglobin ibu hamil
Authors: Agustina Winda , Harahap Hasanah Pratiwi , Oktafirnanda Yuka , Sembiring Elya Rosa Br
Published: January 2024

Pendahuluan: Masa kehamilan ibu hamil harus mendapatkan nutrisi yang banyak, seperti jumlah kalori, protein, zat besi, lemak yang berguna untuk pertumbuhan janin dan untuk kesehatan ibu. Kekurangan nutrisi dapat menyebabkan anemia, abortus, dan komplikasi lainnya. Negara Indonesia, anemia disebabkan oleh kekurangan zat besi, sehingga lebih dikenal dengan istilah anemia gizi besi. Anemia defisiensi besi merupakan salah satu gangguan yang paling sering terjadi selama kehamilan. Zat besi banyak ditemukan diberbagai sumber makanan diantaranya buah bit. Metode Penelitian: Jenis penelitian kuantitatif dengan metode pre eksperimental design dengan desain one group pretest- posttest design. Lokasi penelitian ini di Desa Helvetia Kecamatan Sunggal Kabupaten Deli Serdang. Sampel dalam penelitian ini adalah ibu hamil dengan teknik total population. Intervensi berupa pemberian jelly buah bit. Pengukuran kadar hemoglobin pada ibu hamil dilakukan dengan pengecekan kadar Hb menggunakan pemeriksa Hb digital Easy Touch sebelum dan sesudah intervensi. Analisis data yang digunakan adalah analisys of varians dengan  tingkat  kemaknaan  95%  (0,05). Hasil: Hasil penelitian ini adalah  rata-rata hitung (mean) pretest dan posttest kelompok jelly buah bit adalah sebesar 1.1375 dengan nilai Sig. (2-tailed) adalah 0.007 dimana <0.05 maka ada perbedaan antara rata-rata hitung (mean) pretest dengan posttest kelompok jelly buah bit Kesimpulan: Dari penelitian ini dapat disimpulkan bahwa pemberian jus buah bit meningkatkan Hb pada ibu hamil trimester III. Hasil penelitian ini diharapkan dapat membuat ibu hamil trimester ketiga dapat mengonsumsi jus buah bit atau makanan penambah hemoglobin lainnya setiap hari.
STUDI TEKNIK PENGELOLAAN KUALITAS AIR PADA PEMELIHARAAN INDUK UDANG VANNAMEI (Litopenaeus vannamei) DI PT. SURI TANI PEMUKA UNIT HATCHERY SINGARAJA, BALI
Authors: Maknun Lu’lu’il , Sumsanto Muhammad
Published: January 2024

Vannamei shrimp (Litopenaeus vannamei) is one of the brackish water commodities that is in great demand by the public because it has economic value and is one of the leading products in the aquaculture sector in Indonesia. The purpose of this research was to study and find out about techniques for measuring air quality in rearing vannamei shrimp broodstock at PT. Suri Tani Pemuka, Singaraja Hatchery Unit, Bali. This research method is carried out by measuring and controlling air quality in containers that will be used for vanname shrimp broodstock cultivation activities. Air quality management activities in the maintenance of vaname shrimp (Litopenaeus vannamei) broodstock starts from the initial preparation, namely the sterilization of maintenance air media through the mixing process, sedimentation process, pressure filter, ozonation process, and finally the treatment process. The results of checking air quality carried out every day by measuring the parameters DO the result are 4,4-5,1 ppm, pH 7,6-7,8, Suhu 28,3-28,5oC, Salinitas 30-31 ppt, Alkalinitas 111-113 ppm, Nitrit (NO2) 0,11-0,4 ppm, Amonium (NH4) 0,55-0,87 ppm, obtained the results of air quality measurements that were still at optimal levels that supported the life of the vanname shrimp broods that were reared .
EFEKTIVITAS PROGRAM INOVASI BIDANG PERIKANAN DI KABUPATEN BANYUWANGI
Authors: Shinta Hiflina Yuniari  , Yuniartik Mega
Published: January 2024

Program inovasi tebar ikan terkendai di Kabupaten Banyuwangi bertujuan sebagai pemanfaatan sumberdaya ikan dan berkelanjutan guna meningkatkan taraf hidup/kesejahteraan masyarakat serta mendukung ketahanan pangan lokal. Hal tersebut didukung dengan setiap tahunnya pemerintah Kabupaten Banyuwangi melalui bidang perikanan Dinas Perikanan mengalokasikan anggaran kegiatan berupa penebaran benih ikan air tawar terkendali (barkanli). Namun saat ini belum diketahui seberapa efektif kegiatan tersebut bagi lingkungan dan ekonomi masyarakat. Penelitian ini bertujuan mengetahui efektivitas dan optimalisasi inovasi perikanan tebar benih ikan terkendali di Kabupaten Banyuwangi, serta rekomendasi bagi peningkatan efektivitas inovasi. Metode penelitian ini adalah deskriptif, dengan jenis data yang digunakan adalah penelitian survei (survey research) menggunakan pendekatan kuantitatif dan Focus Group Discussion (FGD. Analisis data menggunakan analisis regresi linear berganda dan analisis SWOT. Hasil penelitian menunjukkan bahwa variabel ekonomi berpengaruh negatif terhadap efektivitas program Barkanli, sedangkan variabel lingkungan berpengaruh positif terhadap efektivitas program barkanli.
DANOS CARDIOVASCULARES PÓS COVID-19: UMA REVISÃO
Authors: Carmo Rafael Leão , Nascimento Geovanna Maria Gonçalves , Pacheco Junia Nunes , Nunes Natália Quinan Bittar , Gonçalves Thatyana Siqueira , Pina Guilherme Cristovam , Barbosa Roberta Perillo , Filho Paulo Roberto Nunes , Inácio Jordanna Porto , Crespo Brena Terra
Published: January 2024

A Covid-19, causada pelo coronavírus SARS-CoV-2, emergiu como uma pandemia global, impactando a saúde pública, economias e sociedades ao redor do mundo. A Covid-19, além de seus sintomas respiratórios característicos, também demonstrou ter impactos significativos no sistema cardiovascular. Diante disso, o estudo foi desenvolvido com o objetivo de elucidar os danos cardiovasculares pós Covid-19. Para o desenvolvimento da presente revisão de literatura, foram utilizadas buscas nas bases de dados SciELO, PubMed e BVS.  A procura dos trabalhos relacionados foi realizada através da aplicação dos descritores “Danos Cardiovasculares” e “Pós Covid-19” nas línguas: português e inglês. Como resultado, foi visto que os principais danos cardiovasculares foram tamponamento cardíaco hemorrágico, choque cardiogênico fulminante, insuficiência ventricular direita, pericardite aguda, miocardite aguda e sobretudo, infarto agudo do miocárdio. Conclui-se, portanto, que é de suma importancia realizar o acompanhamento desses danos para uma maior redução do impacto na qualidade de vida dos pacientes.
Produção de soluções aquosas a partir de plantas medicinais com atividade antiparasitária
Authors: Aquino Alves Maria Heloísa , Da Silva Maria Clara , Da Silva Matheus Givanildo , De Lima Tiburcio João Wictor , De Lima Sá Teles Eduarda , Souza Guinho Gleiciane Adrielli , Da Silva Gustavo Henrique , Muller Zigmundo da Silva Leite Alexandre , Torres de Melo Maria Luisa , Teixeira Macêdo Nathalya , Quirino Alves Gabriela , Pereira Cordeiro Risonildo
Published: January 2024

O uso terapêutico das plantas medicinais é uma prática ancestral que tem evoluído com os avanços na área científica, sendo possível acompanhar os seus efeitos e promover a utilização dos fitoterápicos, até mesmo como terapia complementar contra parasitoses. No Brasil, as políticas nacionais garantem o acesso seguro e o uso racional de plantas medicinais e fitoterápicos, devido à sua eficácia no atendimento primário à saúde. Esse trabalho visou produzir soluções aquosas com plantas medicinais já inseridas no cotidiano populacional para combater a atividade parasitária, sendo elas: Eucalyptus globulus, Mentha crispa, Petroselinum crispum, Coriandrum sativum e Punica granatum. Para tanto, extratos brutos secos hidroalcoólicos foram produzidos, utilizando o método de maceração e posterior rotaevaporação para secagem. Foram preparadas soluções aquosas nas concentrações de 5mg/ml, 2,5mg/ml, 1,25mg/ml e 0,625mg/ml de todos os extratos, posteriormente, foram determinadas a atividade antiparasitária frente aos cistos de Giardia sp e de Entamoeba sp. Para a observação da toxicidade das soluções, foi utilizada a técnica de Artemia salina. As soluções aquosas de Eucalyptus globulus e Punica granatum, apresentaram resultados de atividade frente aos microrganismos testados, a toxicidade foi expressiva para as soluções de Petroselinum crispum e atóxica para Punica granatum e Coriandrum sativum. Todas as soluções aquosas expressaram boa estabilidade. Desta feita destaca-se o potencial e a importância da pesquisa para validação e aprimoramento terapêutico, permitindo que estudos posteriores sejam realizados.
HARMONIZAÇÃO OROFACIAL NA ACADEMIA: UM OLHAR SOBRE O CONHECIMENTO DE DOCENTES E DISCENTES DE ODONTOLOGIA
Authors: Moura José Allysson , Corrêa Ana Karina Fonseca de Carvalho Calderan , Pereira Déborah Yara Sarmento de Abrantes , Matos Samuel Oliveira , Nogueira Marcela Brenda Né , Fernandes Talitha Maryam , Dias Evelyn iara Ferreira Melo , Rodrigues Bhenazyr Nunes , Cruz Simara Silva da , Pinheiro Rebeca Thalita Félix de Lima , Silva Raylena de Andrade Catunda da
Published: January 2024

O presente estudo tem como objetivo analisar o estado atual do conhecimento dos discentes e docentes de odontologia em relação à harmonização orofacial e investigar a integração dessa especialidade nas estruturas curriculares dos cursos de graduação e pós-graduação. Para isso, realizou-se uma revisão integrativa com abordagem qualitativa de natureza exploratória. Para o levantamento dos artigos na literatura, realizou-se uma busca nas seguintes bases de dados: 1) Biblioteca Virtual em Saúde; 2) Periódico CAPES e 3) Google Acadêmico. A análise dos estudos selecionados, em relação ao delineamento de pesquisa, pautou-se em Polit, Beck e Hunglere LoBiondo-Wood e Haber, sendo que tanto a análise quanto a síntese dos dados extraídos dos artigos foram realizadas de forma descritiva, possibilitando observar, contar, descrever e classificar os dados, com o intuito de reunir o conhecimento produzido sobre o tema explorado na revisão. Com relação aos resultados, a busca nas bases de dados identificou 4317 artigos: 10 capturados pela BVS, 06 pela Capes e 4333 pelo Google Acadêmico. Após a análise de títulos e resumos, 128 artigos foram selecionados para a leitura na integra. Com base nos critérios de inclusão e exclusão do presente estudo foram selecionados 07 artigos para a amostra final. Diante disso, este estudo destaca a importância crescente da Harmonização Orofacial (HOF) na odontologia, abordando o reconhecimento formal como especialidade em 2019. Apesar desse avanço, há desafios no conhecimento das legislações por parte de docentes e discentes, evidenciando a necessidade urgente de capacitação para uma prática ética. A pesquisa revela a percepção positiva sobre a inclusão da HOF na matriz curricular, enfatizando sua relevância na formação acadêmica. A capacitação dos dentistas na HOF é crucial para garantir a qualidade e segurança dos procedimentos estéticos e funcionais. A inclusão de disciplinas específicas desde a graduação prepara os profissionais para uma abordagem integrada na saúde bucal. O estudo reconhece limitações, sugerindo que futuras pesquisas explorem o impacto da inclusão da HOF nas grades curriculares e integração de conhecimentos éticos e legais. Em conclusão, destaca a necessidade de medidas educacionais e regulatórias para fortalecer a prática ética e legal da HOF na odontologia.
Strategi Penerapan Bauran Pemasaran Pada Kegiatan “Semarang Heritage Family Run 2022”
Authors: Feisyah Alifah Andini  , Anisatul Auliya
Published: January 2024

In the research, the researcher aims to explore the 7P marketing mix strategy carried out at the "Semarang Heritage Family Run 2022" activity. This research used qualitative methods and research techniques through observation, interviews, and literacy studies. The results of this research lead to the results of the 7P marketing mix analysis carried out by the organizers of this activity so that careful planning is created, and the activity is successful and in demand. The research results showed that the application of the marketing mix used was effective in planning the maturity of event activities. The application of the marketing mix starts from determining the product that will be used as the core material of the planned activity, determining the price, the location of the activity, the promotion carried out, the human resources involved, physical evidence as material for consideration by potential activity participants, and the process as a series of implementation flows, assessed is quite good and has a positive effect on the satisfaction of activity participants.
MICROBIOTA INTESTINAL E SUA RELAÇÃO COM O CÂNCER: UMA REVISÃO INTEGRATIVA
Authors: Lucas Falco Mateus , Huebra Matheus Soti , Panko Caroline Candeo , Bringel Isadora Luísa Borges , Cunha Noélia Claudino Solidade da , Propécio Ana Maria Teixeira , Ramos Giovanna Silva , Santos Josilayne Varela , Westphal Leandro , Faust João Alvim , Rosa-Ribeiro Rafaela
Published: January 2024

A microbiota intestinal é uma vasta colônia bactérias, fungos e vírus que interages com as células hospedeiras para regular uma série de funções fisiológicas no organismo. Quando bem estabelecida, possui capacidade de ativar células do sistema imunológico iniciando uma resposta imune de combate a vários agentes infecciosos e até mesmo células cancerígenas. Entretanto, quando desequilibrada, pode desencadear efeitos contrários. O objetivo desta revisão foi analisar a relação entre o microbioma intestinal e o tratamento oncológico. Foram utilizados as bases de dados PubMed, Medline e LILACS "microbioma intestinal” e “câncer” e “terapia”. Encontrou-se 524 artigos e aplicou-se os critérios de inclusão/exclusão, foram selecionados 22 artigos para leitura completa. Observou-se em vários estudos que as estratégias disponíveis para alterar a microbiota intestinal para auxiliar no tratamento oncológico são o transplante de microbiota fecal, o uso de probióticos e modificações na dieta. Além disso,  microrganismos intestinais podem produzir toxinas, devido às cepas bacterianas, as quais estimulam o crescimento de células imunológicas no revestimento intestinal produzindo uma grande ação inflamatória que pode evoluir para o câncer. Entretanto, quando bem programado, o microbioma intestinal pode ajudar na resposta terapêutica do câncer, reprogramendo as células imunes dentro dos tumores, aperfeiçoando um microambiente imunológico anticancerígeno. Quando desbiose, por conta de fatores genéticos, uso de medicações como antibióticos e maus hábitos alimentares propiciam a proliferação de agentes infecciosos, atenuando a atividade do sistema imune antitumoral.
EuZ – Zeitschrift für Europarecht – Jahrbuch 2023
Authors: Burri Mira , Cardinaux Basile , Freese Benedikt , Gortsos Christos V. , Hakenberg Waltraud , Holznagel Bernd , Jentsch Valentin , Lock Tobias , Reiterer Michael , Schären Simon , Tobler Simone , Trüten Dirk , Weber Rolf H. , Yildiz Okan , Zihlmann Zaira
Published: January 2024

Das vorliegende Jahrbuch umfasst die Leitartikel der EuZ – Zeitschrift für Europarecht aus dem Jahr 2023. Die EuZ berichtet im nunmehr 25. Jahrgang über die jüngsten Entwicklungen im Recht der EU sowie über die Beziehungen der Schweiz zur EU. Im Rahmen wissenschaftlicher Beiträge analysieren renommierte Expertinnen und Experten aktuelle Rechtsfragen in allen wirtschaftsrelevanten Bereichen des EU-Rechts.
Financial inclusion as an indicator of national security
Authors: Oleynikova Lyudmila , Cherep Alla , Budko Danylo
Published: January 2024

The prerequisites for forming national security based on the creation and use of financial inclusion are studied. The essence of the concept of financial inclusion as a component of national security is defined. The expediency of its implementation for all segments of the population is substantiated. It is emphasized that financial inclusion is one of the five directions of the Strategy for the Development of the Financial Sector of Ukraine until 2025 and has specific strategic goals and performance indicators that are related to the level of public confidence in the financial system, the level of financial literacy of the population, and is reflected through the ratio of non-cash card transactions (including P2P) to the total number of transactions and the ratio of cash to GDP. An analysis of the indicators of the level of financial inclusion, which forms the basis of the Strategy for the Development of Ukraine's Financial Sector until 2025, shows that the current values of the indicators do not correspond to their target values. The carried-out analysis made proposing options for developing financial inclusion possible, considering its strategic vectors. In dynamics, the level of public awareness of the use of financial products in Ukraine and other countries worldwide is analyzed. A forecast of the use of financial products by number and type for 2023 – 2024 is made. Positive changes in awareness of financial products in Ukraine have been noted. The expediency and necessity of applying financial inclusion to ensure national security are substantiated. It is noted that the issue of financial inclusion has become especially relevant in the context of the Russian-Ukrainian war. The Top 4 financial products in terms of recognition in the context of age groups are analyzed, and the difference by age categories is reflected. The methods of applying financial inclusion are allocated, and the main aspects that affect it are identified. The main aspects of the information platform on the National Bank of Ukraine website, which is the formation and development of financial literacy among all strata and age categories, are studied. It is noted that financial literacy measures, which the National Bank of Ukraine initiated, require the support of partners.
Keywords: financial inclusion, financial service, financial product, financial literacy, protection of user rights, National Bank of Ukraine.
Application of Instrumental Music in Reducing Anxiety in Priority 4 Patients in the Emergency Room
Authors:   STIKES Dirgahayu Samarinda, Feneranda Tambi Imelda , Hurai Rufina ,   STIKES Dirgahayu Samarinda, Tutik Ismiati Theresia ,   STIKES Dirgahayu Samarinda
Published: January 2024

Background: The Emergency departments have a busy, noisy environment and can cause anxiety to patients. Patients who come to the emergency room have increased anxiety due to the unfamiliar environment, crowds, and actions that are carried out quickly. The increasing level of anxiety can have an effect on the pain experienced by the patient. Priority 4 patients usually suffer from an acute incident with a stable condition and often have a long waiting time. Management of anxiety and pain in patients is not only done by using medical and invasive therapy. Independent nursing interventions can also be carried out by nurses. Interventions to deal with anxiety in the emergency room are very important. The actions taken should be able to help the patient to adjust to the emergency room environment and the various actions taken. Purpose: To determine the effect of music therapy to reduce anxiety in priority 4 patients in the emergency department. Methods:This research method was quasi-experimental, the sampling technique used is purposive sampling. The population in this study was priority 4 patients in the Emergency Room. The instrument used to measure anxiety was the State Anxiety Scale. This study consisted of a control group and a treatment group of 45 respondents. Data analysis used the Wilcoxon test and used SPSS 23 software. Result:There is an influence of Instrumental Music Application in Reducing Anxiety in Priority 4 Patients in the Emergency Room with a significance value of 0.013 Conclusion: The Use of Instrumental Music Can Reduce Anxiety in Priority 4 Patients in the Emergency Room Music therapy can be given as a nurse's independent intervention to prioritize 4 patients in emergency departments. Music therapy canreduce the patient's anxiety level about noise and the actions taken in the emergency room Keywords: Anxiety, Emergency Departements, Music Intervention
The Application Of Telerehabilitation To Post-Stroke Patients In The Covid-19 Pandemic Era
Authors:   Universitas pelita harapan, Fiske Rumambi Magda , Maxmila Yoche Arkianti Maria , Lidya Rumerung Christie
Published: January 2024

Background: Stroke is a cerebrovascular disease that causes sudden death. The blockage causes a lack of oxygen supply which can cause rupture of the arteries to the brain and death of the cells. The COVID-19 pandemic has affected stroke care through various aspects, many of which are associated with neurological symptoms and complications that occur due to delays in treatment. Therefore, the application of telerehabilitation can help support and care for patients with stroke by reducing the risk of transmission of COVID-19. Purpose: The aim of this study was to analyse the application of telerehabilitation to post-stroke patients during the COVID-19 pandemic. Method:The research method is in the form of a systematic review with literature search on primary sources online database, namely PubMed, Medline, and Google Scholar with a range of 2019 to 2021, selection of studies using a meta-analysis approach by answering questions using the PECOT/PICOS framework and analyzed using simplified approach. In this study, the number of articles found was 889 articles with six articles meeting the inclusion criteria. Results: The results of this study indicate that telerehabilitation is effective for stroke patients, but providing telerehabilitation must pay attention to the patient's and family's ability to use digital technology, the ability to understand rehabilitation programs, and also various aspects such as functional status: direct motor skills involving the upper extremities, balance, cardiorespiratory fitness, cognitive function, and the level of acceptance and eligibility of teletherapy by users (patients/families) at home so that the therapy program can run optimally. Conclusion: Telerehabilitation is effectively implemented in the era of the COVID-19 pandemic because it can provide support and help patients, families, and health services in providing care for stroke patients while reducing the risk of transmission of COVID-19. Keywords: Stroke; Pandemic; COVID-19; Telerehabilitation
HEALTH LOCUS OF CONTROL ON COPING MECHANISMS OF CHRONIC RENAL FAILURE PATIENTS WITH HEMODIALYSIS THERAPY AT BLAMBANGAN HOSPITAL BANYUWANGI
Authors:   Stikes Banyuwangi, indriani indriani Ninis , Erna Damayanti Fransiska , Saily Zakiah Iftitah
Published: January 2024

Background: Patients with chronic kidney failure (CKD) require hemodialysis therapy for a long time which can cause patients to experience stress. Stressful conditions in patients with CKD affect coping mechanisms. One that affects the coping mechanism of people with CKD is belief (locus of control). Purpose: This study aimed to determine the correlation between the health locus of control and the coping mechanisms of CKD patients undergoing hemodialysis. Method: The type of research used was a correlation study with a cross-sectional research design. The total sample is 88 respondents with a purposive sampling technique. Data collection used the MHLCS (Multidimensional Health Locus of Control Scale) questionnaire and the Jalowiec Coping Scale. Data were analyzed using the Fisher's Exact test. Results: This study showed that almost all respondents have a high health locus of control with coping mechanisms; most of the respondents fall into the adaptive category. The data analysis showed a significant correlation between health locus of control and coping mechanisms in CRF patients on hemodialysis therapy. Conclusion: Hemodialysis patients with high health locus of control have adaptive coping mechanisms. For respondents to remain in adaptive coping, spiritual activities are needed to guide people with CKD so that they are much more willing to accept their health conditions sincerely. Keywords: Chronic kidney failure; hemodialysis; Health locus of control; coping mechanisms
Islamic Microfinance an Instrument for Poverty Alleviation in Pakistan: A Case Study of Sindh
Authors: Shaikh Asif Zaheer
Published: January 2024

This study aims to investigate how Islamic microfinance can be utilised in Pakistan to alleviate poverty and encourage long-term development. Additionally, it examines the fundamental ideas of Islamic finance and the connection between sustainable development and real economies. The survey was conducted in Sindh; Province of Pakistan. It was observed that despite number of non-Muslim are living in Sindh; Islamic Microfinance does not hindered by any religion. The study also discovered that Islamic Microfinance combined with an appropriate framework for monetary and fiscal policy, have a favourable impact on Pakistan's efforts to reduce poverty.

 

Received: 10 November 2023 / Accepted: 29 December 2023 / Published: 5 January 2024
Front Office Service Recovery at Wyndham Palembang Hotel
Authors: Hariman Hariman
Published: January 2024

One way to find out guests' needs and wants is by listening to complaints. Complaints are usually received by hotels when a service failure has occurred. These results show that service recovery is a complex process where everything must be taken into account in ensuring that guests are happy when they check out. In this study, the determination of informants was carried out using purposive sampling technique. Informants in the study were determined to be parties who were considered capable of providing the information needed, namely Front Office employees at Wyndham Opi Hotel, Palembang. The purpose of this research is to analyze optimal guest satisfaction is important in operations in the Front Office Department at Wyndham Opi Hotel, Palembang, if guests have complaints during their stay at Wyndham Opi Hotel must be given a solution to their discomfort.

Keywords: Front Office, Service, Recovery
Analisis Faktor-Faktor Yang Mempengaruhi Minat Kunjungan Wisata Pantai Padang, Sumatera Barat
Authors: Novesar Muhammad Refki
Published: January 2024

Pantai Padang adalah sebuah pantai yang terletak di Kota Padang, Sumatra Barat. Pantai ini terletak pada kawasan padat perkotaan di Kecamatan Padang Barat penulis ingin mengetahu bagimana faktor kemudian apa yangmemberikan pengaruh terbesar, Pada penelitian ini responden yang di gunakan adalah wisatawan yang mengunjungi pantaipadang lebih dari 2 kali sebanyak 150 responden Dengan perhitungan sampel sampel Metode yang digunakan dalam penelitian ini adalah purposive sampling dengan lima (5) faktor variable yaitu; Mutu Produk Wisata, Citra Produk Wisata, Nilai Pelanggan, Daya Tarik Produk dan Minat Kunjungan Ulang dengan Pengujian hipotesis penelitian dilakukan dengan regresi hasil kesimpulan menjelaskan bahwa variable faktor mempengaruhi minat kiunjungan wisatawan terhadap jumlah wisatawan yang dating, dengan hasil analisis yang signifikan. Yang mana dalam penelitian ditemukan bajwasannya wisatawan tertarik untuk mengunjungi pantai padang untuk keduakali atau bahkan lebih. Dimana memperhatikan mutu, citra, nilai konsumen dan daya Tarik dari pantai ini sendiri. Dengan keunggulan yang dimiliki tentunya menjadi poin penting bagi wisata pantai padang.

Keyword : Mutu Produk Wisata, Citra Produk Wisata, Nilai Pelanggan, Daya Tarik Produk, Minat Kunjung Ulang.
Post COVID-19 Sequelae in Adults: A Review
Authors: Permatasari Devina Indah
Published: January 2024

Post-COVID syndrome is a multisystem disorder that develops after an acute illness. Numerous studies of past respiratory virus pandemics have shown persistence of various symptoms, fatigue, shortness of breath, and cognitive dysfunction that are frequently mentioned. The research carried out use a systematic literature search, a systemic search of published was performed in the databases PubMed and ScienceDirect. To find papers search terms “Post COVID-19”, “SARS-Cov-2”, “Sequelae” and “Adult”. The online search performed between December 2022 to April 2023. The results from the 14 journals used in this study consisted of 9 journals with cohort studies, 3 journals cross sectionals, 2 journals systematic reviews. Fatigue was the most common sequelae (71,4%), shortness of breath (64,1%), anxiety/depression (35,7%), memory and attention deficits (21,4%), myalgia/joint pain (21,4%), Smell/taste disorders (21,4%), hair loss (14,2%), and (7,1%) weakness legs, pain when breathing, cough, tiresness, headaches, problems seeing or blurred vision, hyperhidrosis, insomnia, sore throat, rhinitis, diarrhoea, ageusia, impaired pulmonary function, abnormal CT findings including pulmonary fibrosis, incurred greater risk of heart failure. There are many Sequelae in post COVID-19 sufferers, this will affect the target organs in the body. Fatigue is the most reported sequelae.
Promosi Kesehatan berbasis Kartu untuk Meningkatkan Motivasi Lansia: Alternatif Media Pendidikan Kesehatan
Authors: Wahyudi Donny Tri , Octamelia Mega
Published: January 2024

Memberikan informasi kesehatan tentu menjadi tantangan agar tujuan dari pendidikan kesehatan itu tercapai. Maka, kebutuhan akan media promosi kesehatan tentu menjadi upaya agar informasi tersebut dapat di terima dan implementasi yang dilakukan memberikan dampak positif terhadap motivasi lansia. Metode penelitian menggunakan one group pre post test design. Teknik pengumpulan data menggunakan kusioner. Populasi lansia berjumlah 50 responden. Teknik pengolahan data dengan uji wilcoxon dengan signifikansi (p < 0,05). Hasil penelitian menunjukan terdapat perbedaan motivasi sebelum dan sesudah diberikan media cetak kartu tentang spiritual dan senam otak dengan p = 0,000 (p < 0,05). Di dukung dengan faktor motif pada motivasi yaitu sebagian besar lansia memiliki keluarga, teman dan adanya kegiatan aktivitas setiap minggu di lingkungan. Revisi media kartu yang di rancang membutuhkan revisi pada ukuran tulisan dan gambar.
Simultaneous pickup and delivery model suggestion for personnel transportation in COVID-19 pandemic conditions
Authors: Köse Erkan , Kokmazer Ahsen , Vural Danışment , Gökceolğu Gökçe Gül , Şavlı Pınar
Published: January 2024

The impact of COVID-19 on the transportation costs of a large-scale company has been examined. Before the pandemic, shift personnel were transported to the factory by shuttles, and after a quick shift change, other shift personnel were transported back to their homes. However, with the implementation of laws mandating the reduction of shuttle seat capacities, transportation costs have risen significantly. To address this issue, a new simultaneous Pickup and Delivery Model is proposed as an alternative to the separate transportation of shift workers. The results of this study indicate that the proposed model provides a substantial advantage in terms of both the number of vehicles used and the total distance travelled, leading to a significant reduction in costs. This research underscores the importance of effective operations research practices for the profitability of companies, particularly in extraordinary circumstances such as the COVID-19 pandemic.
Assessing telecommunication contractor firms using a hybrid DEA-BWM method
Authors: Valizadeh Omid , Ghiyasi Mojtaba
Published: January 2024

Telecommunication companies have an important role in technology development, so evaluating the performance of these companies has been an interest of managers. This article uses a hybrid method using data envelopment analysis (DEA) and the best-worst method (BWM) to measure the performance of communication companies. The hybrid DEA-BWM method is used for the weight determination and performance assessment of 17 telecommunication contractor firms in the Khorsan Razavi province of Iran. We considered four inputs: gross losses, sales cost, legal reserve, and fixed assets. On the other side, three outputs including operation income, operation profit, and retained earnings are considered as outputs. Considering the input-output parameters and using the hybrid method by seven selected criteria, we rank all contractor firms. We found that the BPM firm has the best performance while and GKS firm is found as the firm with the weakest performance. Compared with the classical DEA methods, we found more reliable results with higher discrimination power, using the hybrid DEA-BWM.
Comparison of the Stress Analysis To Obtain The Tensile Properties of Three Type-1 and Type-3 Collagen Membranes
Authors: Lima Sousa Leandro Lécio de
Published: January 2024

The aim of this study is to evaluate the mechanical tensile strength for control and specification of three collagen membranes, cross-linked and non-cross-linked, as well as their stress–strain curve. The treatment of sequelae caused by destruction of the periodontal structure resulting from periodontal disease, especially the treatment of alveolar bone defects, known as guided bone regeneration (GBR), is generally aimed at restoring the periodontal insertion apparatus, with the possibility of structural support of membranes and/or barrier, and has been widely studied. Depending on the reaction to their biological environment, membranes can be grouped into two types: resorbable membranes, which, due to biological degradation, induce a tissue response that can negatively affect wound healing and complicate regeneration; and non-resorbable membranes, which have proven to be effective in preventing the invasion of connective and epithelial tissue in the healing area. Resorbable membranes have a high potential for application in periodontal and peri implant regeneration, which indicates collagen as the main extracellular component involved in processes, including cell migration and differentiation. Descriptive statistics of quantitative variables were made by calculating the mean, standard deviation, and standard error; the number of observations was also considered. Statistical inference was applied based on one-way analysis of variance (ANOVA) in the comparison of means in three types of membranes (Bioguide, Jason, and Lumina Dermal) for four dependent variables: elastic modulus (GPa), maximum load (N), breaking stress (MPa), and breaking strain (%). The mechanical characteristics of collagen membranes can be influenced by the action of glutaraldehyde, creating a cross-linking structure in the collagen matrix, thereby substantially increasing the mechanical properties of the membrane; on the other hand, this also increases cytotoxicity. Otherwise, the search for natural collagen membranes with good fixation properties is difficult, due to membrane standardization. Nonetheless, through dimensional and mechanical measurements, it is possible to mechanically qualify collagen membranes and compare them. When assessing the physical stress and tensile properties of the three membranes, high levels of mechanical strength were observed, especially in the Lumina Dermal membrane by Criteria Biomateriais, which presents higher rates based on the methodologies and tests applied, mainly when compared to other samples.
Efficacy of Eggshell-Derived Calcium Phosphate Cement Over Synthetic Hydroxyapatite in Intraosseous Defects: A Randomized Controlled Split-mouth Trial [Retracted/Withdrawn]
Authors: Rath Subha Narayan
Published: January 2024

The author has decided to retract this article in order to conduct further studies and provide an updated version.
Application of HBOT and Wolf Grafting in Chronic Diabetic Foot Ulcer
Authors: Slater Gordon
Published: January 2024

Diabetic foot ulcers are a serious complication of poorly controlled diabetes, often leading to amputations. This study presents a 60-year-old man with diabetes and severe foot ulcers who opted for a Wolfe skin graft with Hyperbaric Oxygen Therapy (HBOT) instead of amputation. Key points of study 1. The patient had poorly controlled diabetes and severe foot ulcers, resulting in 2 amputated toes. 2. Further amputations were anticipated for a chronic Wagner 3 diabetic ulcer. (Wagner, et. al., Foot and Ankle international) 3. A Wolfe skin graft limited debridement and minimally invasive surgery followed by HBOT sessions were successful in healing the ulcers and saving the toe. 4. This approach shows promise as an alternative to amputation for diabetic foot ulcers, potentially reducing costs and improving patient outcomes. Overall, this study suggests that Wolfe skin grafting combined with HBOT can be a viable alternative to amputation for treating diabetic foot ulcers. This approach may offer cost savings and improved quality of life for the patient by preserving limbs.
POSTCOVID-19 War Era, Transformation of the Medicare and Medicaid are Underestimated
Authors: Badlou Bahram Alamdary
Published: January 2024

Transformation of medical sciences into liberal marketing ploys that are dramatically accelerating mortality and morbidity rates in this post-Covid-19 era in a dramatically unknown way becomes big concern. Emergency medicine Sciences need new updates regarding certain Medicare and Medicaid of the unknown visiting random ICU-patients. Which aspects are unknown in this postcovid-19 era? Recent approaches clearly are showing a limited capability to a certain frontier, a kind of “lack of know-how” to prevent rapid and severe emergency-related Medicare and Medicaid of different diseases [1-5].