bluuebunny/crossref_metadata_2025 huggingface dataset:
Digitale Partizipation in hybriden Realitäten und Gemeinschaften
Authors:   Technische Universität Dresden, Center for Open Digital Innovation and Participation (CODIP, Köhler Thomas , Schoop Eric ,   Technische Universität Dresden, Fakultät Wirtschaftswissenschaften, Kahnwald Nina ,   Hochschule der Deutschen Gesetzlichen Unfallversicherung (HGU) Bad Hersfeld, Sonntag Ralph ,   Hochschule für Technik und Wirtschaft Dresden, Fakultät Wirtschaftswissenschaften
Published: February 2022

Die Pandemie hat der Digitalisierung in Wirtschaft, Wissenschaft, Bildung, privaten Netzwerken und öffentlichen Institutionen einen enormen Anschub ermöglicht und gleichermaßen innovative Ideen sowie Schwachstellen aufgezeigt. Seit 2020 wurde unser Leben und Arbeiten zu einer hybriden, auf digitaler Kommunikation und Kollaboration basierten sozitechnischen Wirklichkeit transformatiert. Teilhabe gestaltet sich vermehrt medial, erfasst Bildung, Wirtschaft, Wissenschaft, Privates und die Gesellschaft ganz allgemein. Dabei geht mitunter noch um Infrastrukturen (in der Bildung), oft diskutieren wir Arbeitsweisen und ebenso häufig dafür erforderliche (Digital-) Kompetenzen, gerade auch bei einer alternden Bevölkerung. Debatten drehen sich verstärkt um die Möglichkeit der Rückkehr zum ‚normalen‘ Leben und wir stellen uns immer häufiger die Fragen was den ein Normales Leben ist und ob dies tatsächlich zu erwarten bzw. erwünscht ist.
Co-construction of the general interest and social innovations forms in Kabylia
Authors: Ahmed Zaïd Malika
Published: February 2022

In its theoretical approach, this contribution draws outlines of the conceptual framework of the co-construction of the general interest, and social innovation. It also includes an empirical approach through the results of surveys among concerned social economy associations and public actors in territory of Kabylia (Algeria). It focuses on characterization of social innovation carried by these organizations in relation of public offer, and analysis of its impacts on community and territory. Then, social innovations’ forms of institutionalization were investigated and the institutional predispositions to shared territorial governance that integrates innovations in the economic and social services delivery were identified. Subsequently, we assessed the contributive capacity of the public economy and social economy organizations to the construction of the general interest policies. From there, we were interested in the induced interaction between the various partnerships’ forms what we called “public-community”, “public-social” and “publicinternational” observed in three case studies in the investigated territory. We have characterized social innovation types of the associations that manage community projects in different SSE activities. Their contribution to provide social and economic services for the general interest has been assessed. Finally, we attempted to prove the relevance of forms of governance integrating the co-construction of the general interest in the provision of social services and the forms that the institutionalization of the social innovation takes for the public authorities in the field studied.
From public ownership back to commons
Authors: Vameșu Ancuța , Barna Cristina , Opincaru Irina
Published: February 2022

This chapter is an analysis of the forest commons in Romania (in Romanian - „obște”, „composesorat”) as social solidarity economy organisations mainly looking at how the collective production of norms in these new (re-instituted after 50 years) organisations impacts the sustainability concerns in the collective management of natural goods and production of new goods and services of interest to the community. The chapter has four parts: the first part is offering to the readers a conceptual framework of common goods in order to better understand the particular situation of Romanian natural resources (forests, pastures) as common goods and their transition from public management to commons across time; the second part is a brief history of commons in Romania covering evolutions from 1948 to 2012 and including estimates of the size of surfaces they manage; the third part studies the commons as social economy organisations using key social and economic indicators of commons as SSE organisations from the Prometeus research project in which the authors were involved; and the last part assesses the disposition of the commons for a public, community interest mission and sustainable management of forests using survey data analysis. The chapter thus provides an in-depth analysis of commons as social solidarity economy organisations in Romania and of their capacity to provide a viable framework for sustainably managing the common resources under circumstances of significant economic pressure.
Accountability and transparency policies in Austrian Public-Owned Enterprises (POEs)
Authors: Grüb Birgit , Greiling Dorothea
Published: February 2022

Public owned enterprises (POEs) are important to the daily lives of citizens. As they provide employment as well as services of general economic interest. Nevertheless, researchers also indicate negative side effects like undermining political control, accountability or public ethics. Fully public or partly privatized POEs have to balance the interests of society for service provision and the economic interests of shareholders. The paper gives an overview about accountability and transparency policies in Austrian Public Owned Enterprises.
Introduction
Authors: Zatti Andrea
Published: February 2022

Chapter 1 presents the main concepts and definitions considered in the following analysis (corruption, corruption measures, corruption effects, Public Owned Enterprises-POEs) and the overall structure of the study. A specific focus is dedicated to the notion of hybrid organizations presented as simultaneously quasi-public subjects and enterprises. Due to the coexistence of private-oriented and publicoriented traits, POEs represent an interesting context of analysis in order to study the adoption of anticorruption and compliance measures on forms of control and accountability aiming at removing or mitigating the factors that make more difficult the accomplishment of their original assignments and results. Through a multi country-perspective, the study aims understanding the state of implementation of different anti-corruption and compliance measures in POEs in several European countries; a relatively new subject and one lacking in-depth theoretical and research exploration
Methods to Calculate Electronic Excited-state Dynamics For Molecules on Large Metal Clusters with Many States: Ensuring Fast Overlap Calculations and a Robust Choice of Phase
Authors: Chen Hsing-Ta , Chen Junhan , Cofer-Shabica Vale , Zhou Zeyu , Athavale Vishikh , Medders Gregory , Menger Maximilian , Subotnik Joseph , Jin Zuxin
Published: February 2022

We present an efficient set of methods for propagating excited-state dynamics involving a large number of electronic states based on a configuration interaction singles (CIS) electronic state overlap scheme. Specifically, (i) following Head-Gordon et al, we implement an exact evaluation of the overlap of singly-excited electronic states at different nuclear geometries using a biorthogonal basis, and (ii) we employ a unified protocol for choosing the correct phase for each adiabat at each geometry. For many-electron systems, the combination of these techniques significantly reduces the computational cost of integrating the electronic Schrodinger equation and imposes minimal overhead on top of the underlying electronic structure calculation. As a demonstration, we calculate the electronic excited-state dynamics for a hydrogen molecule scattering off a silver metal cluster, focusing on high-lying excited states where many electrons can be excited collectively and crossings are plentiful. Interestingly, we find that the high-lying, plasmon-like collective excitation spectrum changes with nuclear dynamics, highlighting the need to simulate non-adiabatic nuclear dynamics and plasmonic excitations simultaneously. In the future, the combination of methods presented here should help theorists build a mechanistic understanding of plasmon-assisted charge transfer and excitation energy relaxation processes near a nanoparticle or metal surface.
Hydroxy groups enhance [2]rotaxane anion binding selectivity
Authors: Goodwin Rosemary , Docker Andrew , MacDermott-Opeskin Hugo , Aitken Heather , O'Mara Megan , Beer Paul , White Nicholas
Published: February 2022

We report the synthesis of two [2]rotaxanes containing an interlocked three dimensional binding cavity formed from a pyridinium bis(amide) axle component containing two phenol donors, and an isophthalamide based macrocycle. In the competitive solvent mixture 1:1 CDCl3:CD3OD, one of the receptors exhibits a much higher selectivity preference for chloride than an analogous rotaxane without the hydroxy groups. X-ray crystal structures reveal the chloride anion guest encapsulated within the interlocked binding cavity, though not all of the hydrogen bond donors are utilised. Computational semiempirical simulations indicate that secondary intermolecular interactions occur between the axle hydroxy hydrogen bond donors and the [2]rotaxane macrocycle components, contributing to a more preorganised binding pocket, which may be responsible for the observed enhanced selectivity.
Top-Down Synthesis of Luminescent Microplastics and Nanoplastics by Incorporation of Upconverting Nanoparticles for Environmental Assessment
Authors: Yakovenko Nadiia , Amouroux Baptiste , Albignac Magali , Collin Fabrice , Roux Clément , Mingotaud Anne-Françoise , Roblin Pierre , Coudret Christophe , Ter Halle Alexandra
Published: February 2022

The occurrence of micro- and nanoplastics is a major environmental problem. Especially for nanoplastics due to their easy bioavailability and unknown impact on living organisms. The monitoring of these extremely small particles during their ingestion, tissue translocation and transfer through the trophic chain remains very challenging. This study aims to develop an environmentally relevant model of luminescent micro- and nanoplastics. First, lanthanide-based upconverting nanophosphors (20 nm) were incorporated in bulk polyethylene without modification of the polymer structure or morphology. Second, micrometric and nanometric particles were obtained after powdering. Two fractions were obtained with cascade filtration with average sizes of 5 µm and 150 nm and characterized in terms of size distribution, morphology and surface charge. The particles are very polydisperse with an irregular shape and a global negative charge; they exhibit morphological characteristics similar to those formed in the environment. Their luminescent properties upon NIR excitation at 980 nm open the possibility to track them in the tissues of organisms. The powdering method is very simple and compatible with many polymers pure or formulated. As a perspective, the use of weathered materials is possible with the proposed method and will allow the preparation of particles sharing additional properties with environmental micro- and nanoplastics.
The m6A(m)-independent role of FTO in regulating WNT signaling pathways
Authors: Kim Hyunjoon , Jang Soohyun , Lee Young-suk
Published: February 2022

FTO and ALKBH5 are the two enzymes responsible for mRNA demethylation. Hence, the functional study of FTO has been focused on its mechanistic role in dynamic mRNA modification, and how this post-transcriptional regulation modulates signaling pathways. Here, we report that the functional landscape of FTO is largely associated with WNT signaling pathways but in a manner that is independent of its enzymatic activity. Re-analyses of public datasets identified the bifurcation of canonical and noncanonical WNT pathways as the major role of FTO. In FTO-depleted cells, we find that the canonical WNT/β-Catenin signaling is attenuated in a non-cell autonomous manner via the up-regulation of DKK1. Simultaneously, this up-regulation of DKK1 promotes cell migration via activating the noncanonical WNT/PCP pathway. Unexpectedly, this regulation of DKK1 is independent of its RNA methylation status but operates at the transcriptional level, revealing a noncanonical function of FTO in gene regulation. In conclusion, this study places the functional context of FTO at the branch point of multiple WNT signaling pathways and extends its mechanistic role in gene regulation.
mRNA COVID-19 vaccine booster fosters B- and T-cell responses in immunocompromised patients
Authors: Azzolini Elena , Pozzi Chiara , Germagnoli Luca , Oresta Bianca , Carriglio Nicola , Calleri Mariella , Selmi Carlo , De Santis Maria , Finazzi Silvia , Carlo-Stella Carmelo , Bertuzzi Alexia , Motta Francesca , Ceribelli Angela , Mantovani Alberto , Bonelli Fabrizio , Rescigno Maria
Published: February 2022

SARS-CoV-2 vaccination has proven effective in inducing an immune response in healthy individuals and is progressively us allowing to overcome the pandemic. Recent evidence has shown that response to vaccination in some vulnerable patients may be diminished, and it has been proposed a booster dose. We tested the kinetic of development of serum antibodies to the SARS-CoV-2 Spike protein, their neutralizing capacity, the CD4 and CD8 IFN-γ T-cell response in 328 subjects, including 131 immunocompromised individuals (cancer, rheumatologic, and hemodialysis patients), 160 health-care workers (HCW) and 37 subjects older than 75 yr, after vaccination with two or three doses of mRNA vaccines. We stratified the patients according to the type of treatment. We found that immunocompromised patients, depending on the type of treatment, poorly respond to SARS-CoV-2 mRNA vaccines. However, an additional booster dose of vaccine induced a good immune response in almost all of the patients except those receiving anti-CD20 antibody. Similarly to HCW, previously infected and vaccinated immunocompromised individuals demonstrate a stronger SARS-CoV-2–specific immune response than those who are vaccinated without prior infection.
Desain Media Pembelajaran Berbasis Powtoon dalam Teks Iklan untuk Siswa Kelas VIII SMP
Authors: Rofifah Oktavia Dhiya , Rahayu Triwati
Published: February 2022

Penelitian ini dilatarbelakangi oleh adanya media pembelajaran yang kurang aktif, kreatif dan inovatif untuk penunjang proses belajar siswa agar tidak merasa bosan dan siswa mudah meminati untuk proses pembelajaran. Kelebihan media powtoon ini mencakup segala aspek indera suatu jenis media berbasis audio-visual. Tujuan penelitian ini adalah untuk mengembangkan desain media pembelajaran teks iklan berbasis Powtoon untuk siswa kelas VIII SMP. Metode penelitian ini menggunakan jenis penelitian pengembangan R & D (Research and Development) di mana jenis penelitian ini merupakan metode yang biasa digunakan dalam menghasilkan suatu produk.  Hasil analisis media pembelajaran yang telah dikembangkan menunjukkan bahwa produk yang dikembangkan masuk ke dalam 3 tahap yaitu (analysis) yang terdiri dari analisis materi, analisis kurikulum dan analisis kebutuhan peserta didik , kedua yaitu (design) desain produk pada penelitian ini dimulai pada tahap penyusunan materi sesuai dengan KI dan KD yang telah dipilih, ketiga yaitu (development) dalam kegiatan pengembangan ini mempunyai beberapa tahap dengan menyiapkan alat dan bahan yang digunakan, mengembangkan kerangka media yang telah dibuat sebelumnya menjadi suatu produk media pembelajaran yang akan diterapkan.
Urgencias Médicas Clínico Quirúrgicas
Authors: Ortiz Dueñas Silvio Eleuterio , Muñoz González Violeta Monserrate , Rivas Jiménez Patricia Jamilex , Navas Macías Karen Estefanía , Engel Arrieta Karla Patricia , Vera Vera Jeniffer Stephania , Dorado Riera Mayra Alexandra , Benavides Cárdenas Amanda Gabriela , León Flores Kimberly Johanna , Reyes Martínez Kerly Elizabeth , Loor Vera Ipatia Vanessa , López Zavala Emma Liz , Troya García Manuel de Jesús , Maigua Jarrin Andrea Nicole , Martínez Calderón Tatiana Sofía
Published: February 2022

URGENCIAS MÉDICAS CLÍNICO QUIRÚRGICAS es un libro que se abraza al manto de la urgencia médica considerada como toda situación que, desde el punto de vista médico, plantea una amenaza para la salud o vida de una persona. Lo cual comprende todo aquel problema patológico que se presenta como nueva enfermedad o como descompensación de una patología crónica, lo cual implica que de retrasarse su diagnóstico y/o tratamiento, podría agravar o alargar la historia natural de la enfermedad, precisando asistencia de primera, segunda, o tercera prioridad según su envergadura. Por otro lado, se entiende de manera general como una urgencia quirúrgica, todo aquel proceso que sufre un paciente y que si no se opera con carácter urgente pone en peligro la vida de la persona enferma, lo cual requiere un diagnóstico preciso y rápido siendo crucial con el fin de evitar intervenciones quirúrgicas innecesarias y por el hecho de que, en ocasiones, la demora del tratamiento puede condicionar graves complicaciones e incluso ser mortal. En este sentido, al momento de hacer uso de texto se considera imprescindible tener presente una serie de consideraciones bajo las cuales se desplaza y despliega el mismo. La Organización Mundial de la Salud hace referencia a una urgencia cuando la problemática se debe resolver inmediatamente, lo cual implica una acción de resolución sin ningún tipo de demoras ante la dificultad presentada por la persona. En otras palabras, las urgencias médicas se refieren a una situación en donde se requiere asistencia médica en un lapso reducido de tiempo, pero este no implica riesgo en la vida de los que la involucra ni genera peligro en la evolución de su afección. Cuando se habla de urgencia se hace referencia a una evolución lenta y que no necesariamente es mortal para el afectado.
Kelime öğretimi yöntem ve teknikleri
Authors: ÇİÇEK Seher , DİLEKÇİ Atilla
Published: February 2022

Bir dili anlamlı veya görevli birimler olan kelimeler ve yapı oluşturur. Bu iki unsurdan biri olan kelime en az yapı kadar önemlidir çünkü temel dil becerilerinin etkin ve yeterli bir şekilde kullanımı kelime hazinesinin yeterliğiyle doğru orantılıdır. Öğrencilerin sahip olduğu kelime hazinesi onların iletişim ile sosyal becerilerini ve akademik başarılarını etkilemektedir. Bu nedenle okullarda kelime öğretimi hedeflenmektedir. Bu öğretim sırasında kullanılan uygun, işlevsel yöntem ve teknikler; öğretmenler ve öğrencilerin hedefe ulaşmasını kolaylaştıracak, öğrencilerin alıcı ve üretici dil hazinesinin gelişimini destekleyecektir. Alanyazında kelime öğretiminde kullanılabilecek yöntem ve teknikler bulunmaktadır. Bu araştırmada; kelime öğretimi yöntem ve tekniklerinin belirlenmesi, bunların nasıl kullanılacağına ilişkin bilgi verilmesi amaçlanmıştır. Bu amaçla araştırma, betimsel araştırma modellerinden derleme çalışması şeklinde yürütülmüştür. Araştırmaya veri toplamak amacıyla alanyazından araştırma konusuyla ilgili ulaşılabilen çalışmalar incelenmiş; belirlenen kelime öğretimi yöntem ve teknikleri alt başlıklar hâlinde sıralanarak tanıtılmıştır. Araştırma sonucunda kelime öğretiminde kullanılan otuz yedi yöntem ve teknik olduğu belirlenmiş, bunların uygulanma usulleri açıklanmıştır. Açıklanan bu kelime öğretimi yöntem ve teknikleri sınıf içi bireysel ve grupla uygulanabileceği gibi sınıf dışı bireysel ve grupla da uygulanabilir. Bununla birlikte geleneksel kelime oyunlarının yanında dijital kelime oyunları ile kelime öğretimi yapılabileceği görülmüştür. Tespit edilip açıklanan bu kelime öğretimi yöntem ve tekniklerini; öğretmen, ders kitabı yazarı ve alan uzmanlarının kullanabileceği düşünülmüştür.
Yemlihâ-zâde Mustafa Kâmil Efendi’nin hayatı, edebî yönü ve eserleri
Authors: ÖZGERİŞ Mutlu Melis
Published: February 2022

Yemlihâ-zâde Mustafa Kâmil Efendi, 19. yüzyılda yaşamış ve klasik şiir geleneği doğrultusunda eserlerini yazmış bir isimdir. Hayatı hakkında bilgiler çok sınırlıdır. Bursalı Mehmed Tahir’in Osmanlı Müellifleri adlı eserindeki bilgiler ve matbu-el yazması eserlerinde kendine dair söyledikleri onu tanıma hususunda yardımcı olmaktadır. Doğum tarihi bilinmeyen şair, Elbistan’da âlim-kadı yetiştirmede dikkat çeken Yemlihâ-zâde ailesine mensuptur. Kadılık makamında görev yapmış ve 1294/1877 yılında Kayseri kadısı iken vefat etmiştir. Mevlevî olan şair, Arapça ve Farsçaya çok hâkimdir. Özellikle Arapça yazdığı metinler ve şerhler dikkat çekicidir. İslamî ilimlere vakıf olan Mustafa Kâmil Efendi’nin, bu ilimlerde ortaya konulmuş eserleri okuduğu, hadis ve fıkıh gibi alanlarda eserler kaleme aldığı görülmektedir. Ayrıca onun eserlerine bakıldığında, şerhleri dolayısıyla şârihlik yönünün bulunduğu, hatta şairliğinden daha ön planda olduğu anlaşılmaktadır. İslam edebiyatında meşhur eserleri (İmam Bûsîrî’nin Mudariyye Kasidesi, Ka’b bin Züheyr’in Kaside-i Bürde, Kasidetü’l-Bürde adlarıyla bilinen Bânet Suʿâd kasidesi vd.) şerh etmekle birlikte kendi kasidesini de şerh eden müstesna isimlerden biridir. Şerhlerini çoğunlukla Arapça yapsa da Türkçe yazdığı şerhleri de vardır. Yemlihâ-zâde Mustafa Kâmil Efendi, pek çok nazım ve nesir formunda esere sahiptir. Bunların bir kısmına ulaşılamazken; bir kısmıyla ilgili de herhangi bir çalışma yapılmamıştır. Bu çalışmada ise kendisinden hak ettiği kadar bahsedilmemiş şair/şârih ile ilgili bir takım bilgiler verilerek onun tanınmasına katkı sağlamak amaçlanmıştır.
A SYSTEMATIC APPROACH TO SOURCE-SINK MATCHING FOR CO2 EOR AND SEQUESTRATION
Authors: Pasarai Usman , Iskandar Utomo Pratama , Sugihardjo Sugihardjo , S Herru Lastiadi
Published: February 2022

Carbon dioxide for enhanced oil recovery (CO2 EOR) can magnify oil production substantially while aconsistent amount of the CO2 injected remains sequestrated in the reservoir, which is benefi cial for reducingthe greenhouse gas (GHG) emission. The success of CO2 EOR sequestration depends on the proper sourcessinksintegration. This paper presents a systematic approach to pairing the CO2 captured from industrialactivities with oil reservoirs in South Sumatra basin for pilot project. Inventories of CO2 sources and oilreservoirs were done through survey and data questionnaires. The process of sources-sinks matching waspreceded by scoring and ranking of sources and sinks using criteria specifi cally developed for CO2 EORand sequestration. The top candidate of CO2 sources are matched to several best sinks that correspond toadded value, timing, injectivity, containment, and proximity. Two possible scenarios emerge for the initialpilot where the CO2 will be supplied from the gas gathering station (GGS) while the H3 and F21 oil fi eldsas the sinks. The pilot is intended to facilitate further commercial deployment of CO2 EOR sequestrationin the South Sumatera basin that was confi rmed has abundant EOR and storage sinks as well as industrialCO2 sources.
DEVELOPMENT OF ULTRASONOGRAPHY FOR DOWNHOLE WELL INSPECTION
Authors: Widiyanto Gathuk
Published: February 2022

One technique to increase oil production rate in marginal and suspended wells is solving mechanicalproblem. Success parameter to solve the mechanical problem is to identify this problem properly andaccurately. One of the tools to identify the well integrity including mechanical problem in oil and gasindustry is downhole camera used to describe bore hole conditions. Image is very important and is usedas main parameter to determine the production and operation strategy. So, imaging technology transfer isvery important especially on proven technology. Ultrasonography is proven technology in medical disciplineto create image within human body without signifi cant error. This research tries to apply ultrasonographytechnology in oil and gas industry. Recently, design and prototype of downhole inspection tools stage III havebeen completed. Prototype consists of electronic system, mechanical system and information system includedacquisition system. Laboratory test of these tools has been conducted successfully. Acquisition system usesmemory system within dry battery to avoid operation problem at fi eld test. Several advantages of this toolsare the small number data as per user’s required, user friendly and simple in operation.
Guy’s Stone Score: A Predictive Tool for Outcomes of Percutaneous Nephrolithotomy
Authors: Sharif Imran , Khalid Salman El , Shaikh Jahanzeb , Mithani Hammad , Siddiq Awan Adnan , Anis Khan Shariq
Published: February 2022

Background: Predicting stone clearance before intervention can be useful to plan the modality of treatment and calculate the cost of procedures. Therefore, this study aims to determine the frequency of successful stone clearance in a patient undergoing percutaneous nephrolithotomy (PCNL) with different categories of Guy's Stone Score (GSS).

Methodology: A total of 115 patients undergoing standard PCNL from January to December 2018 were included in this study. According to GSS I-IV, patients were then categorized into four groups after having pre-operative Computed Tomography of Kidney, Ureter, and Bladder (KUB). All the patients received standard general anesthesia and underwent standard PCNL in a prone position. The Percutaneous nephrostomy 18-gauge needle is passed into the pelvis of the kidney, Pelvi-calyceal system opacified and confirmed using fluoroscopy, a guidewire is passed, and 30 Fr Amplatz sheath is introduced after serial dilatation. A 26 Fr nephroscope is then inserted through the working sheath, and the stone is fragmented and removed. Finally, a nephrostomy drain tube is kept at the puncture site. The outcome was accessed in terms of stone clearance rate after PCNL on the 2nd postoperative day using the radiological modality of CT-KUB.

Results: Among the 115 patients here were 48(41.7%) categorized as GSS I, 26(22.6%) categorized as GSSII, 20(17.4%) categorized as GSS III, and 21(18.3%) categorized as GSS IV. The overall stone clearance observed was 64.3%, individual stone clearance was GSS I=91.66%, GSS II=53.84%, GSS III=50%, and GSS IV=28.57%. Stone clearance among the different GSS categories was significantly different (p<0.01).

Conclusion: The Guy's Stone Score, based on CT scan findings, is a significant system in predicting successful stone-free rates. It is a convenient, quick, and efficient tool for pre-operative assessment, and it can be incorporated as a mandatory protocol before planning PCNL.
Treatment of 21st-Century typhoid fever in children; open-label mono versus combination drug therapy: A multicenter randomized control study.
Authors: Ghayas Siddiqi Fatima , Rais Heena , Zafar Farhana , . Bina , Anwar Tayyaba , Ally Zain , Kumar Aneel , Saleem Areesha
Published: February 2022

Background: The treatment of 21st Century XDR typhoid fever is potentially life-threatening and endemic in Pakistan, presents a therapeutic challenge as currently there is no universal treatment strategy whether to use monotherapy with meropenum or a combination of meropenum and azithromycin. Our objective was to compare the efficacy of both therapies in complicated XDR typhoid fever in children, regarding defervescence, bacterial clearance time, resolution of complications, hospital stay, and relapse. 

Methodology: This open-label randomized comparative trial was conducted over 18 months at the Department of Pediatrics, Kemari, Clifton and North Campuses, Ziauddin University Hospital Karachi, Pakistan, in which children (aged 6 months to 18 years) with positive blood culture for XDR enteric fever, were recruited into 2 parallel treatment groups (meropenum) and (meropenum+azithromycin combined). Primary outcome viz clinical improvement (resolution of defervescence, complications, and hospital stay) and lab improvement (negative repeat blood culture, 5 days post-treatment), as well as secondary outcome i.e. treatment failure, adverse drug reactions, and relapse of typhoid within 2 weeks post-treatment were monitored.

Results: In the combination group, there was a quicker resolution of fever (5.40 ± 2.17 days vs 6.55 ± 2.77 days in the monotherapy group) as well as complications (3.42 ± 1.97 days vs 4.31 ± 2.71 days in the monotherapy group), resulting in shorter hospital stay (6.94 ± 2.63 days vs 8.08 ± 3.16 days in monotherapy group). 20% had treatment failure in the monotherapy group with a relative risk of 3.55 times more than that in the combination group.  

Conclusion: Combination therapy with meropenum and azithromycin is more efficacious in treating complicated XDR typhoid fever in children than meropenum alone.
Role of Vitamin B-12 in chronic low backache: A comparative study
Authors: Ali Syed Danish , Shah Syed Kamran Ali , Qureshi Muhammad Kamran , Akram Muhammad Aliuddin  , Ali Ahmed , Siddiqui Aslam
Published: February 2022

Background: Chronic low backache is a commonly affecting problem in our population; it has an economic impact due to the consumption of health expenses in its treatment and rehabilitation. Backache interferes with daily activities of life without discriminating age, gender or race, etc. Our study aimed to determine the role of vitamin B-12 in relieving chronic low backache.

Methodology: A comparative study was conducted at Baqai University and Fatima Hospital, Karachi, from May 2019 to April 2020. A total of 496 patients were enrolled and divided into two groups; group I was treated with vitamin B-12 (n=256), and group II (n=240) did not receive vitamin B-12 treatment. Pre-treatment Visual Analog Scale (VAS) score and Oswestry Disability Index (ODI) scores were evaluated. Group II was given calcium supplements and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) for one month, while group I was given intramuscular injections of vitamin B-12 (500 mcg) on an alternate day for a month along with calcium supplements and NSAIDs.

Results: Pre-treatment mean VAS and ODI scores were 6.68 ± 1.45 and 30.11 ± 12.7, while post-treatment VAS and ODI scores were subsequently 3.50 ± 2.07 and 17.73 ± 12.7, respectively. At the end of treatment, a remarkable decrease in ODI and VAS scores was observed after treatment with vitamin B-12 (p<0.05).

Conclusion: Concurrent use of vitamin B-12 in the treatment of chronic backache had a better impact in relieving backache symptoms than those treated without vitamin B-12.
Evaluation of the effects of the black mulberry extract against Diazinon induced hepatotoxicity in albino wistar rats.
Authors: Javed Safiya , Kalhoro Raima , Memon Shahnaz Bano , Zeeshan Nabeela , Shaikh Abdul Majid , Baloch Ghulam Hussain
Published: February 2022

Background: Diazinon is the globally used organophosphorus compound to which humans are exposed through contamination of food and water. Flavonoids in Morus nigra exhibit a wide range of antioxidant, antimicrobial, anti-inflammatory, anti-cancer, anti-radiation properties and have a protective action against oxidative damage and hepatoprotective effects. The study's objective was to evaluate the effects of black mulberry (Morus nigra) extract against diazinon-induced hepatotoxicity in albino Wistar rats.

Methodology: A quasi-experimental study was conducted from August 2019 to January 2020 at the Department of Pathology, Isra University, Hyderabad, Pakistan. Under standard colony conditions, thirty-six healthy male albino Wistar rats weighing between 200 and 300 grams were randomly divided equally into three groups: Group-1 (Control), Group-2 (given 60 mg/kg Diazinon daily for 4 weeks), Group-3 (administered Diazinon 60 mg/kg with 500 mg/kg of Morus nigra extract daily for 4 weeks through orogastric intubation). Hepatic tissue of all groups was observed under the light microscope. At the same time, hepatic serum markers were also analyzed.

Results: A statistically significant decline in the bodyweight and rise in absolute liver weight of group-3 compared with groups-1 and group-2 (p<0.05). Co-administration of Morus nigra significantly lowered serum AST ad ALT levels. Significant histopathological derangement was observed in group-2 hepatic tissues while group-3 rats hepatic tissues had minimal changes and near-normal hepatic parenchyma.

Conclusion: Morus nigra leaf extract has hepatoprotective effects against Diazinon-induced hepatotoxicity in male albino Wistar rats.
Pengembangan Dispenser Hand Sanitizer Automatis Terintegrasi Pendeteksi Suhu Tubuh untuk Pencegahan Penyebaran Covid-19
Authors: Musaruddin Mustarum , Djohar Abdul , Bunyamin Bunyamin , Saparun Muh.
Published: February 2022

The increase in the number of patients who have tested positive for Covid-19 continues to increase very significantly from time to time and there is no certainty when this outbreak will end. Therefore, anticipatory and preventive steps are needed to overcome these problems. One of the efforts to prevent the spread of the Covid-19 virus is to regularly wash hands and use hand sanitizers. However, not everyone is able to prepare hand sanitizers and not all public places are provided with hand washing facilities and hand sanitizers, even if there are, special personnel (operators) are needed to spray sanitizer and check body temperature with a thermo gun from a very close distance, which of course is this. It is also very vulnerable to the transmission of Covid-19. The purpose of this activity is to design and manufacture and provide appropriate technology for hand sanitizers and body temperature detectors to break the chain of the spread of Covid-19. The method used in this activity is to design, manufacture and test automatic hand sanitizer dispensers and disseminate technology at the urban village office in Kendari City. This community service activity has succeeded in producing an automatic hand sanitizer product that is integrated with a body temperature detection system and this tool has been implemented in one of the Kelurahan offices in Kendari City.
Pola Penyakit Dan Terapi Dengan Pendekatan Empirik Simptomatik Di Desa Gunung Sari
Authors: Asmara I Gede Yasa , Rahmat Basuki
Published: February 2022

The recent global economic crisis has resulted in more expensive health care in which, poor families might not get access to proper health care. Furthermore, global warming and pollution could influence change of disease patterns in the world, includes the tropical island of Lombok. For those two factors, it is interesting to know the disease pattern among poor people and also to give positive contribution for free medical care and treatment to them. A survey of disease patterns and free medical care had been done in Gunung Sari village in August 2015. Patient histories were taken using fundamental four and basic seven techniques whereas physical examinations were done by two registered general practitioners. Soon after working diagnosis is confirmed, empiric antibiotic treatment and symptomatic drugs are prescribed to the patients. As a result, 54% of 136 patients are male and 51,4% of them aged from 16 to 59 years old. Upper respiratory tract infections, diarrhea, and skin problems were the three common diseases. As for the empiric antibiotic treatment, Amoxycillin is the common agent used (34%). Moreover, antipyretic and anti-diarrhoea serve as the common symptomatic treatment used (21,3%). In a summary, the disease pattern and type of treatment given to poor people in Gunung Sari village were the same as that in other areas.
Peningkatan Kapasitas Meliponikultur dengan Pengayaan Pakan Lebah Madu di Kelurahan Kahu Kecamatan Bontocani Kabupaten Bone
Authors: Nuraeni Sitti , Budiaman Budiaman , Sadapotto Andi , Baharuddin Baharuddin , Rajab Marwan , Prastiyo Andi
Published: February 2022

The purpose of this community service program is to provide knowledge about the importance of forests, woody forage plants and enrichment of feed types around meliponiculture farmer groups. The methods used in this activity as part of the mentoring are pre-tests, lectures, video screenings, discussions about knowledge of forest bee hunting, trigona beekeeping and the importance of forests and bee feed. The next activity was the distribution of flowering tree seedlings and visits to the meliponiculture location for farmer groups. The result of this community service activity is that the community in Kahu Village can develop knowledge about the material presented by seeing the enthusiasm and appreciation of the participants or members of the farmer groups who participated in the many questions during the discussion. Receipt of plant and tree seeds that are distributed immediately to the plant and group reception during visits to their meliponiculture area. Awareness of planting various types of vegetation and maintaining forests is an important factor for the stability of colony strength and can even increase the beekeeping productivity of all types of bees in Kahu Village, Bontocani District and its surroundings. Assistance from various parties is needed in order to increase the productivity of honey bee cultivation in Kahu Village, Bontocani District.
Pengenalan Media Digital Pada Usaha Mikro Kecil dan Menengah (UMKM) Melalui Diskusi dan Sharing di Desa Bukit Tinggi Kecamatan Gunungsari
Authors: Arbain Arbain , Koko Arman , Hadi Artam , Nurcahya Baiq , Al Fayet Dodi , Akbar Fathullah , DS Lalu Rizky , Hadi M.Sopian , Setiawati Pasrah , W Rizky Gagah , EP Salsabilla Aurelia , Haryantini Baiq Azizah
Published: February 2022

This activity aims to introduce digital media to Micro, Small and Medium Enterprises (MSMEs) actors, in Desa Bukit Tinggi. The introduction was carried out with the method of discussion and sharing about digital media to promote the results of MSMEs. The targets of this discussion and sharing are teenagers, MSME actors and Bukit Tinggi Village administrators. Resource persons, namely students of the Communication Science study program and digital media experts from HSG Media. During this discussion and sharing, participants were introduced to digital and technical media in making materials to complement digital media, participants be able to create good and correct and interesting content starting from the process of creation, editing to the process of being posted on social media. For sustainability, participants are expected to be practitioners or initiators in managing digital media as a forum for MSME activists to market products or crafts produced by the local community. Participants' interest and enthusiasm for the material provided was quite high, as seen from the many questions from participants and discussions with resource persons to deepen and strengthen knowledge in digital media.
Teknik Bedeng Permanen Alternatif Mengurangi Biaya Produksi Usahatani Pada Kondisi Pendemi Covid19
Authors: Soemeinaboedhy I Nyoman , Padusung Padusung , Kusnarta I Gusti Made , Mahrup Mahrup , Fahrudin Fahrudin
Published: February 2022

Permanent raised-beds can be used in several soil seasons and aim to increase production through the application of sustainable and sustainable agriculture and can improve the welfare of farmers. The three basic principles of conservation agriculture are: i) applying minimal or no tillage ii) applying cover crops continuously throughout the year, and iii) applying crop diversification, either by intercropping, crop rotation, and consecutive cropping (relay cropping), especially between non-legume and legume crops. Service activities provide knowledge to farmers by demonstrating the application of permanent bed farming techniques to reduce farm production costs. This activity is expected to: 1) as an example of the application of permanent bed-based agriculture to prevent soil erosion by planting cover crops and mulch, 2) as an example of a permanent bed technique to maintain soil stability and save costs, 3) as an example of a natural way to restore physical, chemical and biological fertility of dry soil, and 4) as an example of how to increase soil productivity in dry paddy fields typology. To achieve this, several conservation methods will be introduced, as well as several types of vegetable crops and minimum tillage techniques will be introduced.
The Concept Of Property And Welfare Through Abu Ubaid
Authors: Muchtar Evan Hamzah , Supriadi Supriadi , Rahmawati Destiani
Published: February 2022

This research discusses wealth and welfare through the thought of Abu Ubaid, who is known as the Amwal and Al-Kharaj books. The problem of this research is related to taxes and zakat which are managed by the state which are not in accordance with their designation, in the sense that the current tax is burdened more on Muslims than on importers or non-Muslims. The purpose of this research is that the thoughts of Abu Ubaid regarding wealth and welfare can be an inspiration for our country in managing taxes and zakat. The research method used in this research is using qualitative research, descriptive analytical, the data used in this research is secondary data from previous studies. The results of this research show that the concept of wealth and welfare of Abu Ubaid's  is good and very relevant to be applied in Indonesia.
Audit Zakat Research: A Bibliometic Analysis
Authors: Taqi Muhamad , Sabaruddinsah Sabaruddinsah , Rusydiana Aam Slamet
Published: February 2022

This research aims to find out the trend of the development of research maps with the theme of zakat audit published by reputable journals related to Islamic economics and finance. There were 113 indexed research publications analyzed in this study. Then the data was processed and analyzed using R Bliblioshiny software to find bibliometric maps related to economic development and Islamic finance in zakat audit research. It was found that the publication of research related to the theme experienced a significant increase, and the majority of documents were in the form of journal articles. The most famous author is Sofyani H, and the most popular keyword topics are zakat and accounting. The contribution of this research is expected to be able to strengthen the transparency and accountability of the public social sector in this case the zakat institution so as to increase public trust.
Entrepreneurial Practice in Trading on Javanese-Muslim Ethnicity and Chinese-Confucian Ethnicity in Kanoman Market, Cirebon City
Authors: Cahyono Heru
Published: February 2022

In the practical realm, the market always provides room for contestation for the entrepreneurs involved in it. Likewise, in Kanoman Market, Cirebon City, this ethnic entrepreneurial contestation was represented by the two so-called ethnic groups, namely the Javanese-Muslim ethnicity and the Chinese-Confucian ethnicity. The contestation in the entrepreneurial field at Kanoman Market shows the dominance of confident entrepreneurs. For example, service entrepreneurs (corporate entrepreneurs) of Javanese ethnicity and entrepreneurs of essential commodities (trading entrepreneurs) are generally ethnic Chinese. The purpose of this study is to analyze the entrepreneurial contestation of Javanese-Muslim ethnicity and ethnic Chinese-Kunghucu at Kanoman Market, Cirebon. The research uses qualitative methods with an anthropological-economic approach. They are then equipped with data analysis to answer research questions. This study found that the entrepreneurial contestation of Javanese-Muslim and Chinese-Kunghucu ethnics in Kanoman Market, Cirebon City, the economic practices of the two ethnicities were carried out and shaped by the belief system of the community, whether influenced by the religious belief system adopted or the belief system sourced from ethnic values and the ethnic belief system. For this reason, in economic practice, especially in the contestation taking place in the market, the belief system forms its influence in accepting the Javanese-Muslim and Chinese-Kunghucu ethnicities on matters relating to the belief system they believe in. In their entrepreneurial practice, the two ethnic groups involve social capital and mystical capital, such as a network of associations and professional organizations, as well as mystical elements, such as prayer rituals and amulets of sellers.
The Effects Of Risk Based Bank Rating On Stock Return During Covid-19 Of BUKU IV Banks In Indonesia
Authors: Daryanto Wiwiek Mardawiyah , Meiliawati Putri Tresna
Published: February 2022

On December 31, 2019, the Wuhan City Health Commission, China, announced a cluster of cases of pneumonia, which causes the disease Covid-19. Indonesia's Gross Domestic Product (GDP) began to weaken at the end of the first quarter of 2020 from 4.9% to 2.9% (Q-o-Q), and then declined sharply in the second quarter of around -5.32%. The next quarter still saw negative growth but with less severity. Due to the Covid-19 crisis, investors began to hesitate to invest and withdraw their funds from the stock market, causing the Indonesian stock exchange (IDX) in Q1-2020 to fall 29.83% (YoY). In addition, it also led to a decline in banking stock prices, where the INFOBANK15 index fell from Rp.1,033.43 in Q4-2019 to Rp.732.54 in Q1-2020, or decreased by 29.12%. This study aims to determine the level of soundness based on the Risk Based Rating (RBBR) and the effect of the health level of the bank on bank stock returns. This research uses purposive sampling technique. RBBR analysis is used to determine the soundness of each RBBR ratio and is obtained from secondary data on the quarterly financial statements of seven publicly audited banks in Q4-2018 to Q1-2021. Banks under BUKU IV are in a healthy and very healthy condition based on the RBBR method, and research shows that NPL, LDR, ROA have a significant and positive effect on stock returns. Meanwhile, NIM and CAR have no effect on stock returns.
Penyuluhan Pencegahan Penularan Covid-19 Pada Penderita Hiv Di Rsud Dr Moewardi Surakarta
Authors: Nurhayatun Evi , Prabowo Nurhasan Agung
Published: February 2022

People with HIV are susceptible to COVID-19 and if they have been exposed to COVID-19, they tend to be more severe than other populations. Kelompok Dukungan Sebaya (KDS) solo plus has problems with personal protective equipment that is not optimal, stress and anxiety, higher risk of infection and lower body resistance. Therefore, it is important to do prevention education, clean and healthy lifestyle, how to take medicine during the pandemic and recognize early symptoms of disease for people living with HIV (PLWHA/people with HIV AIDS). This community service provides a solution by providing information on COVID-19 for people with HIV, providing personal protective equipment and making a safety guidebook for HIV. This activity is going well and supports the prevention of transmission of COVID-19 in HIV sufferers KDS Solo Plus. Suggestions for continuing educational activities like this with a wider range of participants and more creative methods. Penderita HIV adalah penderita yang rentan terkena COVID-19 dan jika sudah terkena COVID-19, mereka cenderung lebih parah dibandingkan populasi lainnya. Kelompok Dukungan Sebaya (KDS) Solo Plus mempunyai permasalahan, yaitu pada alat pelindung diri tidak optimal, stres dan kecemasan, risiko tertular lebih tinggi, dan daya tahan tubuh yang lebih rendah. Oleh karena itu, penting dilakukan edukasi tentang pencegahan, pola hidup bersih, sehat, cara minum obat saat pandemi, dan pengenalan gejala awal penyakit pada orang yang hidup dengan HIV (ODHA). Pengabdian masyarakat ini memberikan solusi dengan cara penyuluhan COVID-19 bagi penderita HIV, pemberian alat pelindung diri, dan pembuatan buku panduan keselamatan pada penderita HIV. Kegiatan ini berjalan baik dan mendukung pencegahan penularan COVID-19 pada penderita HIV KDS Solo Plus. Saran untuk melanjutkan kegiatan edukasi seperti ini adalah dengan cakupan peserta lebih luas dan metode yang lebih kreatif.