bluuebunny/crossref_metadata_2025 huggingface dataset:
Search for technological opportunities based on the patent array analysis
Authors: Korobkin Dmitriy Mihaylovich , Gorkin Vsevolod Sergeevich , Fomenkov Sergey Alekseevich
Published: November 2023

Currently companies still rely heavily on expert knowledge when searching for technological opportunities and choosing partners. Automation of search of patent holders who can be partners of the enterprises of the Volgograd region is considered. Companies not only from Russia, but also from China, India, and other friendly countries are considered as partners. The process of identifying partners is based on the similarity of solved technological problems extracted from patent documents, the patent holders of which are these enterprises. By analyzing the dependency trees extracted from the patent fields “Scope of the invention” and “Name of the invention” the “Problem-Solution” structures are formed. Based on the analysis of patent documents of potential partners “Problems-Solutions” that are not patented in Russia are identified. It causes a “technological vacuum” for enterprises of the Russian Federation. A method for identifying technological capabilities based on the analysis of the world patent array has been developed. The novelty of the method which provides a search for potential innovative technological areas for key enterprises of the Volgograd region lies in the use of deep learning technologies in relation to the analysis of natural language data of the world patent array. A software module has been developed to search for technological opportunities for enterprises of the Volgograd region based on the similarity of technological problems. The module is programmatically implemented in Python, the Yargy library from the Natasha project was used for semantic analysis of text fields of patents, Deep–translator was used for translating patent documents into Russian, Stanza library was used for building dependency trees, and RuWordNet library was used for selecting hyperonyms (to account for synonymous words). In order to identify technological opportunities for enterprises of the Volgograd region, 6 785 patents were analyzed.
Probabilistic model of limited period liquidity goods sales dynamics
Authors: Mikheev Andrej Vyacheslavovich
Published: November 2023

A probabilistic approach to accounting the impact of a limited period of liquidity on the volume of goods sales has been developed. The approach is based on the assumption of the random nature of economic factors deter-mining the sales dynamics of goods: production moments, purchases moments, liquidity period, quantity of goods and number of consumers. Analytical expressions for the probability function and expected value of the time dependence of the quantity of sold goods in two cases were found: without taking into account and with taking into account the moments of goods production. Numerical modelling of the dynamics of the expected value of the quantity of sold goods is carried out. It is shown that as the number of buyers grows, the market of goods becomes more and more manageable, as the real dynamics of the quantity of sold goods and the dynamics of the expected value of this quantity cease to differ from each other. The general patterns of the joint effect of the parameters of probabilistic distribution laws of the five economic factors mentioned above on the value and dynamics of the sales volume of goods were determined. Within the framework of the proposed probabilistic model, a time dependence approximating the real dynamics of sales of Lada Vesta cars on the Russian market in the period from October 2015 to May 2023 were found.
Organizational Transformation at the Secretariat of the DPRD Takalar
Authors: Maryadi Maryadi , Rahman Nawir , Reynilda Reynilda
Published: November 2023

Organizational transformation in the Regional Representative Council (DPRD) has a high urgency given its central role in the democratic system and public decision-making. This study aims to examine the organizational transformation of the DPRD of Takalar Regency and to analyze the determinant factors in the organizational transformation of the institution. The method used in this research is descriptive with a qualitative approach. The informants for this study consisted of DPRD secretariats, DPRD members, and political party officials, with a total of 21 informants. This research collects primary data through FGD. The results of the study show that organizational transformation at the DPRD Takalar secretariat is carried out to 1) increase efficiency in policy-making and supervising executive performance through optimizing decision-making processes and improving legislative products; 2) strengthen accountability and transparency in DPRD; and 3) strengthening the relationship between the DPRD and the community. DPRD must be an inclusive forum for public participation and community aspirations. Overall, organizational transformation in the DPRD has a high urgency to improve efficiency, accountability, capacity, and relations with the community. By adopting an approach that focuses on system change, organizational culture, and community involvement, DPRD can become a more responsive, effective institution, and able to respond to the challenges faced by society and the state.
OCENA KVALITETA ZAVARENOG SPOJA NA BAZI METALOGRAFSKOG ISPITIVANJA
Authors: Bardak Šušnica Svjetlana
Published: November 2023

U ovom radu izvršeno je metalografsko makro ispitivanje uzoraka u cilju ocene kvaliteta zavarenih spojeva prema standardu SRPS EN ISO 15614-1. Vizuelnim pregledom površine materijala može se samo naslutiti kakvu strukturu ima pa se stoga metalografska ispitivanja obavljaju, između ostalog, u cilju identifikacije makro i mikrostrukturnih grešaka i ispitivanje metalografske strukture u karakterističnim zonama zavarenog spoja: metal šava, ZUT i osnovni materijal. Kao posledica nepoznavanja parametara zavarivanja zbog nedostatka prateće dokumentacije je nemoguće odrediti tačne uzroke nastanka grešaka u zavarenim spojevima. Zbog toga se u analizi makro preseka navode pretpostavke o uzrocima nastalih grešaka.
ПРОЈЕКАТ ПЛОЧЕ ХАЛЕ КАО БЕТОНСКЕ И СПРЕГНУТЕ – УПОРЕДНА АНАЛИЗА
Authors: Филиповић Данило
Published: November 2023

У раду је у првом кораку спрове­дена анализа армирано бетонске подне плоче спорт­ске хале са припадајућим гредама. Анализа оптере­ћења, прорачун, као и димезионисање елемената конструкције извршени су према правилима Еврокод – а. Наведени прорачун и димензионисање су одрађени у програмском пакету „Tower 8“. Након димензиони­сања армирано бетонске,  следећи задатак је био димензионисање замењујуће спрегнуте конструкције. Прорачун спрегнуте плоче спроведен је у програм­ском пакету „SOFiSTiK 2023“. Посебна пажња је посвећена контроли вибрација плоче услед пешачког оптерећења. Разлог за посебан осврт на вибрације плоче лежи у врло битном предуслову квалитета модерних конструкција – самој удобности корисника животног, односно простора пословне намене.
IDEJNO REŠENJE VODOSNABDEVANJA I KANALISANJA NASELJA ČENEJ
Authors: Adžić Dragana
Published: November 2023

Predmet ovog rada je idejno rešenje vodosnabdevanja i kanalisanje otpadnih vod u naselju Čenej, primenom programskih paketa EPA SWMM za kanalisanje otpadnih voda i EPANET za snabdevanje vodom. Broj stanovnika za projektni period od 21 godine u naselju Čenej iznosi 2383. Rad je podeljen u 2 dela.

1.Vodosnabdevanje

2.Kalisanje otpadne vode u naselju Čenej.
ВРЕДНОВАЊЕ ПРЕДЛОГА РЕШЕЊА ЗА ПОБОЉШАЊЕ УСЛОВА ОДВИЈАЊА САОБРАЋАЈА НА РАСКРСНИЦИ БУЛЕВАР ЕВРОПЕ, РУМЕНАЧКИ ПУТ
Authors: Ковачевић Андреа , Богдановић Вук
Published: November 2023

У оквиру рада извршена је анализа услова одвијања саобраћаја на раскрсници Булевар Европе, Руменачки пут у Новом Саду. У складу са добијеним резултатима, дати су предлози решења за побољшање услова одвијања саобраћаја. За сва предложена варијантна решења извршено је функционално вредновање на основу чега је извршен избор оптималног решења.
SAVREMENA KOLIBA – KUĆA ZA ODMOR U NASELJU TABANOVIĆ
Authors: Mirković Jelena
Published: November 2023

U ovom radu istražene su osnovne karakteristike primitivnih skloništa i kuće za odmor, paralela između njih i razvoj kroz istoriju, društvene klase, običaje i stil života korisnika.
Uporedni pristup stvaranja interaktivne scene u odnosu na imersivnost
Authors: Bogavac Dejan , Jovanović Marko
Published: November 2023

Popularnost tradicionalnih Escape Room igara i razvoj imersivnih tehnologija je uticao na pojavu virtualnih Escape Room igara. U ovom istraživanju je ispitana mogućnost predstavljanja koncepta tradicionalne Escape Room igre kroz imersivnost virtualnih igara. Testirane su i vezija igre za računar i verzija za virtualnu realnost.
SUPORT CENTAR
Authors: Šakota Aleksa
Published: November 2023

Usled povećanog broja ljudi koji boluju od depresije, anksioznosti i drugih mentalnih poremećaja, javlja se potreba za objektom koji bi pružio pomoć i utočište tim ljudima. Pojekat Suport centra ima ideju da na jednom mestu pruži svu neophodnu pomoć ljudima u kriznim situacijama. Bio bi opremljen sobama za meditaciju, bazenom, ordinacijama, raznim sadržajem za rekreaciju, kao i japanskim vrtom.
IMPLEMENTACIJA MQTT PROTOKOLA KORIŠĆENJEM ARDUINO 2650 + ESP8266 RAZVOJNE PLOČE
Authors: Boberić Marko
Published: November 2023

U ovom radu, uspešno je imlpemen­tiran MQTT protokol pomoću Arduino Mega 2560 + ESP8266 ploče i besplatne mobilne aplikacije IoT MQTT Panel. Cilj zadatka bio je da se pomoću telefona upravlja sistemom koji izvšava upravljanje stanjem diode, očitavanje temperature, upravljanje otključanosti vrata, detekciju pokreta kao i detekciju plamena.
PENGARUH PRESTASI BELAJAR TERHADAP KEPERCAYAAN DIRI SISWA KELAS X SMA NEGERI 3 PEMALANG
Authors: Farda Mufti Nugraha  , Eka Sari Setianingsih  , Primaningrum Dian M
Published: November 2023

Penelitian pengaruh prestasi belajar terhadap kepercayaan diri siswa kelas X SMA Negeri 3 Pemalang ini dilatar belakangi banyaknya siswa yang mengalami kurang percaya diri. Jenis penelitian ini adalah deskriptif kuantitatif korelasi. Populasi dalam penelitian ini adalah siswa kelas X SMA Negeri 3 Pemalang dengan jumlah 360 siswa. Kelas X.10 adalah kelas yang dilakukan untuk tryout. Sampel dalam penelitian ini yaitu 78 siswa yang diambil dengan teknik cluster random sampling. Alat pengumpulan data yang dipergunakan adalah skala prestasi belajar dan kepercayaan diri. Berdasarkan hasil penelitian diperoleh kesimpulan terdapat pengaruh yang signifikan antara prestasi belajar dengan kepercayaan diri siswa kelas X SMA Negeri 3 Pemalang. Hal ini dibuktikan dari hasil uji korelasi product moment diperoleh nilai sig. (2-tailed) diperoleh 0,004 < 0,05 maka diketahui bahwa nilai koefisien korelasi (r) adalah 0,320 dengan taraf positif. Oleh karena itu nilai koefisien korelasi atau nilai rhitung > rtabel yaitu 0,320 > 0,227. Besarnya determinan sebesar 0,102 yang artinya pengaruh prestasi belajar terhadap kepercayaan diri memiliki pengaruh sebesar 10,2%, sisanya 89,8% dipengaruhi oleh faktor lain yang tidak dianalisis dalam penelitian ini. Sehingga dapat dikatakan bahwa terdapat pengaruh prestasi belajar terhadap kepercayaan diri siswa kelas  X SMA Negeri 3 Pemalang. Dengan demikian menunjukan bahwa semakin tinggi prestasi belajar maka semakin tinggi kepercayaan dirinya.
ANALISIS KONTEN KESEHATAN MENTAL PADA INSTAGRAM STUDIO DJIWA
Authors: Moenandar Vania Enjelita , Adi Wibowo Kunto , Fuady Ikhsan
Published: November 2023

Kesehatan mental merupakan prospek yang sangat penting dalam kesehatan. Banyak orang yang menyadari potensi mereka terkena mental illness yang memungkinkan dalam kesehatan mental yang baik Media sosial menjadi tempat berekpresi terhadap diri sendiri dan sarana edukasi tentang kesehatan mental, salah media sosial Instagram. Pengguna Instagram di Indonesia sudah mencapai 33,90 juta jiwa dan generasi Z Indonesia memposisikan urutan kedua sebagai pengguna Instagram terbanyak di Indonesia. Instagram mempunyai banyak tempat sarana untuk memberi edukasi atau pengetahuan tentang Kesehatan mental, salah satu Instagram yang mengangkat tentang kesehatan mental di sekitar. Studio Djiwa merupakan akun Instagram yang menjadi sarana pengetahuan tentang Kesehatan mental berbentuk infografis komik memiliki 82,3rb pengikut dan 246 postingan yang diunggah. Pada penelitian ini, peneliti mengamati konten Instagram studio djiwa dengan populasi 246 postingan dan 150 sampel menggunakan uji validitas dan reliabilitas, uji frekuensi, dan uji Chi-Square. Data tersebut dikumpulkan dengan sejak postingan pertama yaitu tanggal 20 Mei 2020 – 28 Maret 2022, seluruh postingan studio djiwa dijadikan populasi untuk dianalisis. Berdasarkan hasil penelitian, ditemukan bahwa komposisi gambar dari konten Instagram studi djiwa di dominasikan oleh infografis dan jenis masalah kesehatan mental di dominasikan oleh disorder. Selanjutnya, terdapat hubungan antara variabel kesehatan mental dengan klaim p<0.05 dan tidak terdapat hubungan antara variabel kesehatan mental dengan identitas kelompok sosial disebabkan p>0,05.
REPRESENTASI NILAI BODY POSITIVITY PADA AKUN INSTAGRAM XYZ
Authors: Kautsar Malika Ilma , Fuady Ikhsan , A. Wibowo Kunto
Published: November 2023

Tujuan penelitian ini adalah ingin mengetahui bagaimana representasi body positivity pada akun Instagram. Media sosial merupakan kumpulan berbagai aplikasi berbasis internet yang beralaskan pada teknologi web 2.0. Instagram menjadi salah satu tempat dan wadah gerakan body positivity bergerak. Pada akun XYZ dan apakah terdapat hubungan antara nilai citra tubuh positif dengan nilai penampilan tubuh. Body positivity atau kepositifan tubuh adalah gabungan dari citra tubuh positif, kepercayaan diri, dan ditambah dengan penerimaan atas tubuh tersebut tanpa memandang bentuk serta ukuran. Tuntutan masyarakat mengenai standar kecantikan dan penampilan yang meliputi kulit putih, tubuh langsing, semampai, dan sebagainya seringkali menjadi sumber kecemasan serta kekhawatiran seseorang. Hal tersebut membuat banyak individu yang merasakan tidak percaya diri dan merasa dirinya tidak cukup.Dengan keresahan dan kekhawatiran ini muncul lah tren body positivity sebagai respon atas penerimaan atas tubuh dan penampilan tanpa memperhatikan bentuk dan ukurannya. Harapannya adalah meningkatnya kesadaran masyarakat terhadap penerimaan atas citra tubuh positif setiap individu tanpa ada standar yang tidak realistis. Penelitian ini menggunakan metode penelitian kuantitatif analisis isi dengan uji frekuensi dan uji pearson correlation menggunakan aplikasi SPSS. Populasi penelitian ini adalah postingan pada Instagram XYZ dengan total sampel sebanyak 139 postingan dalam jangka waktu tertentu.
MANFAAT PSIKOLOGIS KEGIATAN MEMASAK: ANALISIS TEMATIK
Authors: Listiani Disa Nisrina , Abidin Zainal
Published: November 2023

Memasak merupakan alternatif rekreasi yang masih jarang diteliti. Telah ada beberapa penelitian intervensi klinis mengenai memasak, namun penelitian yang menggali manfaat psikologis dari kegiatan memasak sehari-hari masih sulit ditemukan. Sample dalam penelitian ini adalah tiga orang yang dipilih melalui purposive sampling. Ketiga subjek memiliki latar belakang dan profesi yang berbeda-beda namun memiliki satu kesamaan yaitu hobi memasak. Wawancara dilakukan secara online melalui Zoom. Teknik analisis yang digunakan adalah analisis tematik. Hasil dan pembahasan dibagi ke dalam dua bagian, yaitu intrakasus subjek dan interkasus subjek. Tema umum yang didapatkan dari hasil wawancara adalah bahwa memasak memiliki manfaat psikologis yang banyak dan beragam, di antaranya: melatih mindfulness, mengurangi tingkat stress dan emosi negatif, melatih kontrol diri, meningkatkan self-worth, serta dapat menjadi wadah untuk mengenali diri sendiri dan bersosialisasi dengan orang lain.
Consumer Representative Actions in the Financial Sector
Authors: Wijayanti Sita Adelia Jatu , Cahyono Akhmad Budi
Published: November 2023

The presence of a non-governmental consumer protection organization plays a vital role in assisting consumers whose position tends to be weak and overseeing the implementation of bank executions so that they are carried out fairly. The organization can also represent a broad group of consumers to appear before the court for consumer protection. This study analyzes the legal protection of consumers based on the omnibus financial law of the Financial Sector Development and Strengthening Law and the Consumer Protection Law as well as the role of non-governmental consumer protection institutions in providing advocacy and consultation to consumers in the financial services sector. This study also addresses the legal standing of nongovernmental consumer protection organizations in court. This study aims to provide an analysis of consumer protection in the financial services sector and the role of nongovernmental consumer protection organizations in their involvement in consumer disputes in the financial services sector. The results of the research are based on case studies, that there are still lawsuits filed by non-governmental consumer protection organizations on behalf of consumers in the financial services sector that do not meet the requirements as stipulated in the Law.
Penguatan Asas Kebebasan Berkontrak Untuk Kepentingan Umum Dalam Layanan Pinjaman Online Dengan Menggunakan Pendekatan Rule of Law
Authors: Harniwati Harniwati , Fauzi Engrina , Fajar Abdul Malik
Published: November 2023

This article analyzes the setting of very high interest rates on information technology-based lending and borrowing services by the Indonesian Funding Fintech Association (AFPI). AFPI was given self-regulating authority by the OJK (Financial Services Authority) to determine loan interest rates which caused disproportionate positions between borrowers and lenders. This research aims to answer problems in terms of the substance of fintech peer to peer lending regulations in Indonesia, so a comprehensive analysis is needed from the perspective of statutory regulations and conceptually so that legal protection can be achieved for the public, especially borrowers. The results of this research show that the unequal position of the parties in fintech agreements is due to a lack of understanding of the principle of complete freedom of contract. The application of the principle of freedom of contract in fintech can be said to be not optimal and still applies artificially due to the urgent interests of borrowers who are in a weak position where urgent needs are forced to agree to agreements with high interest rates. It is necessary to limit the principle of freedom of contract because it has an impact on injustice and in the public interest it is necessary to break through public law into civil law. Apart from that, it is necessary to strengthen the Pancasila economic system again because it is in accordance with the identity of the Indonesian nation. Apart from that, the law must be a determinant of the economy, not as an instrument to support the economic system, thus causing the economy to be more determinant over the law.
Development and prototyping of an innovative design for automatic paper bag making machine
Authors: Nithul P. , Vikas V. K.
Published: November 2023

The Plastic Waste Management Amendment Rules, 2021, already prohibit the manufacture, import, stocking, distribution, sale, and use of plastic carry bags having a thickness of less than 75 microns. They also provide for a ban on plastic carry bags with a thickness of less than 120 microns as of December 31, 2022. So, there is an increasing demand for paper bags. The already existing paper bag-making machines are expensive and consume 25-50 square meters for their operation. A machine whose initial cost is less, which does not require large space consumption and operates with simple technologies, can be used for small-scale production. This will help the manufacturer earn money through the small-scale production of paper bags. The demand for paper bags is continuously increasing, so this project aims to develop an economical and easily fabricable machine with simple methods that promote the use of paper bags instead of plastic carry bags and helps reduce the impact on the environment.
Urban agglomerations: functioning and methodological principles of development
Authors: Suvorova Arina
Published: November 2023

Currently, the development of urban agglomerations is recognized as one of the key prerequisites for accelerating the economic growth of large-scale economic systems. The study is devoted to the conceptual foundations of this process. The author considers the logic of the organization and development of agglomerations; identifies the features of the functioning of agglomerations in modern conditions; studies the principles that should underlie their development. The work is based on the use of data from the Federal State Statistics Service, and its methodological base includes general scientific methods of theoretical and empirical cognition. It is shown that a significant aspect of the functioning of the agglomeration is the close relationship between its elements. The importance of this aspect is also proved by the results of the analysis of the functioning of the Yekaterinburg urban agglomeration, which is characterized by the redistribution of functionality between its constituent municipalities. The suburbs increase their importance as a place to live in and work, while the central parts of the agglomeration retain the role of a service center. As a result of the study methodological principles of agglomerations development are formulated: a differentiated approach to determining landmarks, mechanisms and institutions of transformation processes, institutionalization of the object, the systemic nature of space transformation, the absence of barriers of interaction between elements, the availability of a resource basis for development. The results obtained can be used in the activities of public authorities that determine and implement regional policy.
THE METHOD OF ADAPTIVE SELECTION OF THE SIZE OF TURBO CODE STATE DIAGRAMS IN 5G AND IOT SYSTEMS
Authors:   Central Research Institute of the Armed Forces of Ukraine, Sokorynska Natalia , Posternak Yurii ,   Chernihiv Polytechnic National University, Zaitseva Liliia ,   Institute of Telecommunications and Global Information Space of the National Academy of Sciences of Ukraine, Rudenok Oleksandr ,   Institute of Telecommunications and Global Information Space of the National Academy of Sciences of Ukraine
Published: November 2023

The article proposes a method for optimizing the operation of the turbocode encoder/decoder in 5G and IoT systems due to the adaptive selection of the state diagram size using the proposed decoding uncertainty indicator.The principles of forming state diagrams of the turbo code encoder and decoder are considered, and the uncertainty of data decoding is clarified. Using the a priori and a posteriori data of the turbo code decoder, an algorithm for changing the state diagram of the turbo code encoder/decoder is proposed.The essence of the method is to optimize the operation of the turbo code encoder and decoder by using adaptive selection of the state diagram size using the proposed decoding uncertainty indicator. The implementation of the method will allow to increase the given indicators of reliability of information without reducing the bandwidth of systems and networks of wireless data transmission systems.In contrast to the known results, depending on the signal-to-noise ratio in the channel and the values of the normalized number of sign changes of the a posteriori-prior logarithmic relations of the likelihood functions about the transmitted data bits of the turbo code decoder, an adaptive selection of the state diagram size of the TC encoder/decoder is made.The simulation analysis shows that in order to ensure the given indicators of information reliability, the method selects a rational size of the TC encoder/decoder state diagram, which is confirmed by comparison with other simulation results.The method can be used together with other methods of adaptation, for example, with adaptation of coding speed, poly-nomials of TC component codes, in systems with multi-parameter adaptation operating under conditions of a priori uncertainty. The types of virtual agents in social networks are distinguished: primary source, bot accounts, troll accounts, real people
IRRADIATION COTURNIX JAPONICA EGGS WITH PROTONS IN THE FLASH MODE SHOWED BETTER PRESERVATION OF HEALTHY TISSUES AND ORGANOGENESIS IN EMBRYOS
Authors:   Institute of Theoretical and Experimental Biophysics RAS, Pushchino, Glukhov S.I. , Yakovlev I.A. , Kuznetsova E.A. , Martynova V.V. , Gavrilov Yu.K. , Kokontsev D.A. , Akulinichev S.V. ,   Institute for Nuclear Research RAS, Moscow,   Petrovsky Russian Scientific Center of Surgery, Moscow
Published: November 2023

The paper presents for the first time data on the decrease of the radiotoxicity for FLASH-mode against embrionic development of amniotes’ eggs. Japanese quail (C. Japonica) model was used. Accelerated protons in the Bragg peak were applied to irradiated object.
STUDY OF THE RADIOPROTECTIVE PROPERTIES OF FULLERENOL C60,70 USING BACTERIAL LUMINESCENT BIOASSAY
Authors:   Siberian Federal University, Krasnoyarsk, Grabovoy A.S. , Kolesnik O.V. , Kudryasheva N.S. ,   Institute of Biophysics SB RAS, Krasnoyarsk
Published: November 2023

Radioprotective properties of fullerenol C60,70 were studded using bacterial luminescent bioassay. The results of experiments showed: an activation of bioluminescence by tritium, mitigation of tritium effect by fullerenol, 20 % increase of reactive oxygen species under exposure to fullerenol.
USING OF LONG-TERM LUMINESCENCE OF MOLECULAR PROBES TO ASSESS THE MALIGNANCY OF TISSUES
Authors:   Orenburg State University, Ishemgulov A.T. , Letuta S.N. , Senchukova M.A. ,   Orenburg State Medical University
Published: November 2023

The kinetics of long-term luminescence of xanthene dyes (eosin, erythrosin) in mammary gland tissues in vitro has been studied. Analysis of about 180 samples revealed statistically significant differences in the delayed luminescence between malignant and normal tissues. The differences found are presumably related to the peculiarities of the accumulation and consumption of oxygen in the tissues.
Complicated cataract with iatrogenic capsule defect with silicone tamponade of the vitreal cavity
Authors:   N.I. Pirogov National Medical Surgical Center, Moscow, Russian Federation, Bosov E.D. , Fayzrakhmanov R.R. ,   N.I. Pirogov National Medical Surgical Center, Moscow, Russian Federation, Saraeva S.N. ,   N.I. Pirogov National Medical Surgical Center, Moscow, Russian Federation, Bogdanova V.A. ,   N.I. Pirogov National Medical Surgical Center, Moscow, Russian Federation
Published: November 2023

Цель. Представить вариант транссклеральной фиксации интраокулярной линзы (ИОЛ) у пациента с осложненной катарактой на фоне тампонады СМ. Методы. Пациент К., 46 лет, поступил в НМХЦ им. акад. Н.И. Пирогова с жалобой на низкое зрение правого глаза. В анамнезе: продолжительная силиконовая тампонада после рецидивирующей регматогенной отслойки сетчатки. Vis OD = 0,5, sph –2,75 D = 1,0; Vis OS = proectio lucis certa; внутриглазное давление (ВГД): OD = 12,5 мм рт.ст., OS = 28 мм рт.ст. При осмотре была выявлена эмульгация силиконового масла (СМ) в передней камере, помутнение всех слоев хрусталика. Интраоперационно был обнаружен ятрогенный дефект задней капсулы хрусталика. Выполнена факоэмульсификация осложненной катаракты, транспупиллярное удаление СМ, транссклеральная фиксация ИОЛ, трехпортовый склеральный доступ 25G, эндолазеркоагуляция и эндотампонада газовоздушной смесью С2F6. Результаты. Послеоперационный период проходил без осложнений. Через 1 месяц: Vis OS = 0,05; ВГД = 20 мм рт.ст. Выводы. Ятрогенные дефекты задней капсулы хрусталика при тампонаде СМ у витреоретинальных пациентов осложняются развитием катаракты. Имплантация с подшиванием ИОЛ является оптимальным вариантом хирургического лечения. Ключевые слова: силиконовая тампонада, дефект задней капсулы, транссклеральная фиксация, осложненная катаракта
In silico evaluation of isoflavones for its galactagogue activity in promoting lactation
Authors: Nikkila Devi Ravichandran , Dhisha Vasudevan , Suresh Balasubramanian , Mahalakshmi Sundarapandian
Published: November 2023

Breastfeeding is crucial for the health of both mothers and infants, providing both short-term and long-term benefits. Breast milk contains all the necessary nutrients for both the mother and child. Unfortunately, many women are experiencing a low milk supply, resulting in infants not receiving sufficient immune support. To increase milk production, there are various herbal and pharmaceutical galactagogues available. Plants in the Caryophyllaceae family contain phytoestrogen, a compound that helps stimulate milk production. Isoflavone is one type of phytoestrogens. Isoflavones have many properties like bactericidal, fungicidal and anti-ringworm and are used to treat breast and prostate cancer and bone-related diseases. Spergula arvensis L., a member of the Caryophyllaceae family, is rich in isoflavones. Nine specific compounds were chosen due to their connection to mammary gland function. A preliminary in silico study was conducted to examine the interaction between isoflavones and prolactin receptors through molecular docking. The compound quercetin, an isoflavone, showed a better binding affinity to the receptor.
Normalization of RT-PCR protocol for detecting dengue viral RNA in infected clinical residual serum samples
Authors: Sowrabha Ramachandra , Manjulakumari Doddamane
Published: November 2023

Among mosquito-borne viral infections, dengue tops the list with a high prevalence of all four serotypes, especially in tropical regions. The disease has disseminated in over 100 countries and has become a global threat, mainly affecting young individuals. Detecting the dengue virus in clinical samples has a significant role in diagnosing, treating, epidemiology, surveillance, predicting outbreaks etc. To accomplish this, RT-PCR technology has become a practical way out. Although PCR has reached its cutting edge with its improved versions being available, the conventional form of it has still retained the standard for generating more accurate and reliable results cost-effectively. In the present study, the conventional RT-PCR protocol was normalized for detecting dengue viral RNA in infected clinical residual serum samples by adopting a few previous protocols with required modifications. This procedure, with necessary precautions considered particularly for residual samples, resulted in obtaining expected amplicon bands in three samples. Additionally, Sanger sequencing of the amplicons and NCBI nucleotide BLAST analysis of obtained sequences assured the RT-PCR outcomes. The benefits of using clinical residual samples in dengue research encouraged us to make the PCR protocol suitable for such samples by tackling their limitations.
Apoptotic effect of reduced Graphene Oxide on MCF-7 Breast cancer cell line using Asparagus Racemosus roots
Authors: Leema Rose A. , Janeeta Priya F. , Vidhya S. , Amsica T.R.
Published: November 2023

In the modern era, the major health issue is cancer. Cancer is one of the second- deadliest death-causing diseases worldwide. Graphene is a carbon-based material that has drawn a great deal of attention because of its eccentric chemical and physical properties. Moreover, graphene can be transformed into graphene oxide or reduced graphene oxide, depending on its application. Chemical reduction of graphene oxide was associated with toxic and harmful reducing compounds; hence, the green, efficient and cost-effective approach for graphene synthesis is using plant extract. In this contemporary study, the reduced graphene oxide can be synthesized from Asparagus racemosus root extract, involving anti-cancer activity. The reduced graphene oxide was characterized from UV-Visible, FT-IR, SEM and XRD. The size and shape of the synthesized reduced graphene oxide were confirmed from SEM studies. The anti-cancer activity showed a strong cytotoxic effect on the tested cell line.
Triploidy verification of Schizothorax richardsonii using erythrocyte cell and nucleus measurement
Authors: Rani A. , Siddiqui U. , Ghosh T.K. , Pandey N.N.
Published: November 2023

The individuals of diploid and triploid Schizothorax richardsonii (Gray, 1832) were identified using erythrocyte indices. The Erythrocyte cell's major axis of the triploid was 17% higher than the diploid. The increase in the nucleus major axis size of the erythrocyte of the triploid was also greater by 8% concerning the diploid fishes. The erythrocyte measurement ranged between 13.29±1.06 to 14.45±0.97 for diploid 15.91±1.32 to 16.49±1.23 for triploid erythrocyte nucleus 6.16±0.67 to 6.40±0.63 and 6.70±0.71 to 6.94±0.56 for diploid and triploid respectively. The data were analyzed by One Way of Analysis of Variance (ANOVA) for both diploid (control) and triploid (treated) erythrocyte and nucleus measurement which showed significant differences with p<0.05. These parameters, thus, can successfully be used in discriminating diploid and triploid S. richadrsonii.
An Insight into understanding the Antimicrobial Activity of Coriandrum sativum on Antimicrobial Resistant Strains
Authors: Renganathan S. , Manjunath A. , Chinmayi A.G.V. , Sabat S.
Published: November 2023

This review highlights the growing emergence of antibiotic resistant bacterial strains. Antibiotics are slowly becoming redundant due to various mechanisms adopted by bacterial strains to combat the bactericidal properties of these antibiotics. Hence, the need of the hour is to find alternative methods of treatment of infections caused by these drug-resistant bacterial strains. The use of herbal products could be employed here as one of the possible solutions to curb the spread of bacterial infections. This review focuses solely on skin infections caused by bacteria. Numerous experiments have proven the bactericidal properties of Coriandrum sativum. Here, we explore the possibility of Coriandrum sativum as a solution to antimicrobial resistance.
Understanding of effect and mechanism of abiotic stress tolerance in legumes and recent development
Authors: . Anamika , Saxena Raghvendra , Tomar R.S. , Mishra Raghvendra Kumar
Published: November 2023

The present changing climatic conditions are affecting crop productivity worldwide. The crop growth and productivity are adversely hit by perturbed climatic conditions and climate change. Being sessile, plants are openly exposed to biotic and abiotic stresses which limit the crop productivity. Crop plants exhibit tolerance and susceptibility under adverse conditions through various attributes at different levels like morphological, physiological, biochemical and genetic level, although their magnitude of response varies. Crops responses toward abiotic stresses have increased in the recent years by advancement of technology and understanding of physiology, molecular and genetic level of crops response to these stresses. In the processes of development of stress-tolerant plants, several genes associated tolerance and adaptation get activated leading to modulate several biochemical, physiological and metabolic pathways. Stress also induces the production of reactive oxygen species (ROS) and subsequently change in signal transduction in the plants switches towards enhancement of antioxidant system. Both abiotic and biotic stresses affect all the physiological processes of the legume plants, especially photosynthesis, respiration, water use efficiency, nutrient use efficiency etc. The activity of cell organelles like mitochondria, chloroplast and vacuoles is also affected by stress. The present study is focusing on the impact of diverse abiotic stresses at different levels in legume crops and changes at physiological, biochemical and molecular level. It also discusses the opportunities to ameliorate the ability of the legumes to enhance abiotic stress tolerance for crop improvement and agriculture sustainability.
Mutation breeding as a tool for improving plant characters: A review
Authors: Dhondge K.S. , Maske N.M. , Khemnar A.S.
Published: November 2023

Identifying plants with desirable traits among existing plant varieties is the initial and most important step in plant breeding. Plant breeding requires the genetic variation of useful traits for crop improvement or crop betterment. The plant breeding depends upon the genetic variation. In nature, variation occurs mainly as a result of mutation and without it, plant breeding would be impossible. Mutation as a mechanism of creating variability was identified by Hugo de Vries while experimenting on the rediscovery of Mendel’s Law of Inheritance.17 Mutation arises in two ways; First, spontaneous mutation which occurs without treatment of the organism with an exogenous mutagen and secondly induced mutation which occurs due to the treatment of a plant or plant parts such as seed, stem, cuttings, pollen and ovules with the help of mutagens. The purposeful employment of the induced mutation for crop improvement is known as mutation breeding. The mutation breeding is also known as the variation breeding.There are mainly two types of mutagens (agent to cause mutation) i.e. physical and chemical mutagens. The mutant shows higher potential for improving plant architecture leading to better crop improvement and used as complementary and rational tool in plant breeding. Mutation breeding programme should be clearly planned and should be large enough with sufficient facilities to screen large population in short time. This review highlights the role of mutation breeding in improvement of qualitative and quantitative characters of crop plant.
Amorphous aggregates with a very wide size distribution play a central role in crystal nucleation
Authors: Liao Zhiyu , Das Ankita , Robb Christina Glen , Beveridge Rebecca , Wynne Klaas
Published: November 2023

There is mounting evidence that crystal nucleation from supersaturated solution involves the formation and reorganization of prenucleation clusters, contradicting classical nucleation theory. Here, a range of amino acids and peptides is investigated using light scattering, mass spectrometry, and in situ terahertz Raman spectroscopy, showing that the presence of amorphous aggregates is a general phenomenon in supersaturated solutions. Significantly, these aggregates are found on a vast range of length scales from dimers to 30-mers to the nanometer and even micrometer scale, suggesting a continuous distribution throughout this range. Larger amorphous aggregates are sites of spontaneous crystal nucleation and act as intermediates for laser-induced crystal nucleation. These results are shown to be consistent with a nonclassical nucleation model in which barrierless (homogeneous) nucleation of amorphous aggregates is followed by the nucleation of crystals from solute-enriched aggregates. This provides a novel perspective on crystal nucleation.
Novel Optimization of Photocatalytic Degradation of Wastewater Pollutants Using Piezoelectric and Paraelectric Materials
Authors: Rao Amrutha
Published: November 2023

Wastewater pollution has a detrimental impact on the environment, including harming aquatic ecosystems, causing eutrophication, and posing risks to human health. Existing catalysts commonly used for pollutant degradation in wastewater can demonstrate a low percent degradation of pollutants within certain time periods, have long reaction times, only work under limited conditions, work on a large or small scale, or possess a combination of these limitations. In recent advances, some piezoelectric materials and certain paraelectric materials have been shown to have catalytic activity in degrading pollutants. Lead zirconate (piezoelectric) and strontium titanate (paraelectric) are examples of materials that possess these properties. The purpose of this study was to utilize multiple piezoelectric materials and other catalysts with favorable properties, such as lead zirconate and strontium titanate, to develop a novel catalyst to degrade pollutants in wastewater. In the experiment, catalysts were created by mixing various ratios of lead zirconate, strontium titanate, and titanium dioxide powders–the latter being the currently most used photocatalyst for wastewater purification. These catalysts were added to four different wastewater samples obtained from different sources: three were industrial wastewater samples containing inorganic and organic pollutants with one sample being mixed with dye pollutants in addition. The other wastewater sample was a lab-created solution of methylene blue and water. Each sample of wastewater and catalyst mixed together was subjected to controlled conditions and specified durations of visible and UV light exposure. Spectroscopy was used to analyze the effectiveness of the different catalysts. The absorption of each mixture of wastewater and catalyst was recorded at both the beginning and end of the reaction period and compared, and the percent difference in absorption at peak length between the beginning and end of the reaction period was used to calculate the photodegradation efficiency. The catalyst that was created using a 1:1 ratio of strontium titanate to lead zirconate sample had a 19.57% greater percent degradation efficiency compared to the traditionally used catalyst (titanium dioxide) when both were used on the third industrial wastewater sample under the study’s experimental conditions. A higher percent degradation efficiency signifies a greater a reduction in the initial pollutants. This decrease could potentially signify the breakdown of pollutants into smaller particles, which may be less harmful. The findings in this study underscore the potential of the catalyst, strontium titanate and lead zirconate in a 1:1 ratio, for the use of wastewater treatment and hence to protect the environment from wastewater pollution, possibly with a higher percent degradation efficiency than the currently used catalyst for this application.
A Golden Touch in the Design of Porphyrin Metallacages as Multifaceted Anticancer Agents
Authors: Rodríguez-Prieto Tamara , Wragg Darren , Heiduk Nicole , Park Mihyun , Strittmatter Nicole , Fischer Roland A. , Casini Angela , Moreno-Alcántar Guillermo
Published: November 2023

The use of three-dimensional self-assembled metallacages (MCgs) as theranostic platforms holds great promise. This work reports on the integration of a gold(III) porphyrin scaffold into a prismatic metallacage structure and explores its application for photodynamic therapy (PDT) of cancer in vitro. Not only the new metallacage retains the photosensitizing properties of the gold porphyrin, but unexpectedly, it also shows remarkable selective stabilization of guanine-quadruplexes (G4) structures as validated anticancer drug targets.
Magnetic exchange, anisotropy and excitonic fluctuations in a [NiII7] Anderson wheel
Authors: Brechin Euan , Payne Emily , Singh Mukesh , Nichol Gary , Stewart Ross , Garcia-Sakai Victoria , Ewings Russell , Lane Harry , Schnack Juergen , Stock Chris
Published: November 2023

The solvothermal reaction of Ni(ClO4)2·6H2O with hmpH and picH in a basic MeOH solution affords [Ni7(hmp)7.55(pic)4.45](ClO4)2·6MeOH (1·6MeOH) directly upon cooling the mother liquor. The metallic skeleton of 1 describes a [NiII7] centred hexagon, commonly referred to as an Anderson wheel. Magnetic meaurements reveal ferromagnetic exchange between the central Ni ion and the ring Ni ions, and antiferromagnetic exchange between neighbouring ring Ni ions. They also confirm the presence of easy-plane anisotropy for the central Ni ion, and easy-axis anisotropy for the ring Ni ions, in agreement with DFT calculations and neutron scattering. For the analysis of the latter we apply an excitonic formalism using a Green's function response theory.
Kajian Historisme dalam Cerpen “Yasima Ingin Jadi Juru Masak Nippon” karya Edy Firmansyah
Authors: Putri Lara Anastasya , Hartanto Erika Citra Sari
Published: November 2023

Not too many people use Historicism as a theory in their research. The use of the Historicism approach aims to identify historical events. The source of the data used in this research is a short story entitled Yasima Ingin Jadi Juru Masak Nippon by a writer named Edy Firmansyah. The research method used in this research is a qualitative method. The results and discussion found that the short story of Yasima Ingin Jadi Juru Masak Nippon by a writer named Edy Firmansyah has historical values, most of the parts focus on the wars that occurred in the past when the Madurese people fought against the Dutch and Japanese colonizers. Thus, the researcher hopes that this research can be used as research material by future researchers.
Analisis Kesalahan Ejaan Bahasa Indonesia di Ruang Publik Rumah Sakit Dian Harapan Tahun 2022
Authors: Utami Uma Fajar
Published: November 2023

Public space is a space or land owned by the public, a place for people to do activities, and a place to socialize. The use of the Indonesian language in public spaces is regulated in Law No. 24 of 2009 Article 38 that the Indonesian language must be used in public signs, road signs, public facilities, banners, and other information tools which are public services. This study aims to describe errors in the use of spelling and writing in foreign languages in the public spaces at Dian Harapan Hospital in 2022. This research uses descriptive qualitative methods that is to understand holistically phenomenon by using descriptions in the words and language's form. The data collection method used in the research are observation and documentation of photos and pictures taken from public spaces at Dian Harapan Hospital on August 2002. Based on the research on 50 photos/images of signs in the public space at Dian Harapan Hospital, 2 errors were found in the use of capital letters, 30 errors in writing abbreviations, 1 error in writing prepositions, 1 error in writing numbers, 4 errors in writing commas, 1 error in writing slash marks, and 12 errors in writing exclamation marks. The spelling errors in the public space at Dian Harapan Hospital occured due to a lack of knowledges about spelling rules (EYD V) and the absence of strict and real punishments on the errors and violations in using the language in the public spaces.
Yetişkin Bireylerde Dürtüsellik, Nomofobi ve Kompulsif Çevrimiçi Satın Almanın İncelenmesi (Impulsivity, Nomophobia and Compulsive Online Buying in Adults)
Authors: Subaşı Bingül , Zengin Gizem
Published: November 2023

Bu çalışmanın amacı, yetişkin bireylerin dürtüsellik, nomofobi ve kompulsif çevrimiçi satın alma düzeyinin incelenmesidir. Tarama modeli kullanılarak gerçekleştirilmiş olan bu çalışmanın evrenini Türkiye’de yaşayan 18 yaş ve üzeri yetişkin bireyler oluşturmaktadır. Araştırmanın örneklemine seçkisiz olmayan örnekleme yöntemlerinden biri olan uygun örnekleme yöntemi kullanılarak ulaşılmıştır. Araştırma, Türkiye’de yaşayan 18 yaş ve üzeri 318 kadın ve 101 erkek olmak üzere toplam 419 yetişkin bireyin katılımıyla gerçekleştirilmiştir. Katılımcılara Sosyodemografik Bilgi Formu, Barratt Dürtüsellik Ölçeği, Nomofobi Ölçeği ve Kompulsif Çevrimiçi Satın Alma Ölçeği çevrimiçi olarak uygulanmıştır. Çalışma bulgularına göre katılımcıların nomofobi ölçeği ve ölçeğin alt boyutları ile kompulsif çevrimiçi satın alma ölçeği ve ölçeğin alt boyutları arasında istatistiksel olarak anlamlı düzeyde pozitif yönde ilişki olduğu tespit edilmiştir. Motor dürtüsellik ve dikkat dürtüsellik alt boyutları arttıkça kompulsif çevrimiçi satın alma davranışının arttığı, plan yapma alt boyutu arttıkça kompulsif çevrimiçi satın alma ve alt boyutlarında azalma olduğu tespit edilmiştir. Beklenilmeyen durumları yönetme becerisinin kazanılması dürtüselliği kontrol altına almada yardımcı olabilir.