Clinical evaluation of complex treatment and prevention of generalized periodontitis in patients with type I diabetes mellitus with cardiomyopathy
Authors: Shkrebnyuk R. Y. , Dyryk V. T. , Vynogradova O. M. , Bodnaruk N. I. , Zubachyk O. V. 
Published: November 2021

Annotation. Diabetes mellitus is an acute problem, as evidenced by the large number of people suffering from this disease, and the tendency to significantly increase the incidence rate. The most serious complications of diabetes include cardiomyopathy, the pathogenetic aspects of which are being actively studied. Widespread inflammatory-dystrophic periodontal disease and an increase in the proportion of generalized periodontitis in patients with diabetes mellitus complicated by cardiomyopathy, makes the problem of effective treatment and prevention of this pathology among the most relevant. The purpose of the study: clinical evaluation of complex treatment and prevention of generalized periodontitis in patients with type I diabetes mellitus with cardiomyopathy according to the developed algorithm. Comprehensive treatment and prevention measures were performed in 127 patients with generalized periodontitis on the background of type I diabetes mellitus with cardiomyopathy, of which 82 patients were the main group, where treatment was carried out using our proposed treatment and prevention algorithm. The control group, in which treatment was carried out according to protocol methods, consisted of 45 patients. Clinical visual examination and determination of paraclinical indices were performed on day 30 after treatment. Statistical calculation of digital values was performed on a Pentium II computer using the statistical software package “Statgraphic 2.3” and “Microsoft Excel 2000”, the significance of changes was evaluated by t-test. As a result of the research it was found that on average, 30 days after treatment, in the main group where we used the proposed pharmacotherapy, “normalization” of periodontal tissues was studied in 26.83 % of patients, “improvement” – in 30.49 % of patients’ treatment was ineffective in 42.68 % of patients, with a reliability of p>0.05. In patients of the control group, where traditional treatment and prevention measures were used to treat generalized periodontitis, on average, “normalization” of periodontal tissue was recorded in 17.78 % of patients, “improvement” of periodontal tissue was found in 28.89 % of patients. Treatment was ineffective in 53.33 % of patients. Thus, as a result of research, it can be argued that in patients with generalized periodontitis on the background of type I diabetes mellitus complicated by cardiomyopathy, whose treatment was carried out using our treatment and prevention algorithm, which included local measures and general appointments, significantly improved periodontal tissues, as confirmed by clinical observation. In the control group, where traditional treatment regimens were used, the treatment of generalized periodontitis was ineffective. In further studies, it is planned to study the microbiome of the oral cavity in patients with generalized periodontitis on the background of type I diabetes mellitus complicated by cardiomyopathy.