bluuebunny/crossref_metadata_2025 huggingface dataset:
SEASONAL MICROALTERNATIONS OF ECG SIGNAL IN STUDENTS OF A NOTHERN UNIVERSITY
Authors: Pogonysheva I. A. , Lunyak I. I. , Pogonyshev D. A
Published: June 2020

The research addresses the seasonal dynamics of electrophysiological properties of the myocardium in students who live and study in the Khanty-Mansi Autonomous Okrug -Yugra, Russia. The main method of the research was the dispersion mapping of low-amplitude cardiocycle oscillations. The indicators of the electrophysiological properties of the myocardium were recorded in the Human Ecology Laboratory of Nizhnevartovsk State University using the CardioVisor-06s computer-based heart screening system. Eighty 2nd and 3rd year students participated in the research. Microalternations of the ECG signal were recorded four times per year, once in each season. The electrophysiological activity of the myocardium was analyzed and showed seasonal dynamics. The myocardial microalternation index and the Rhythm indicator increased from summer to winter and reached maximum in spring. Increased integral indicators of dispersion mapping in spring may indicate the climatic impact. The transitional season puts greater stress on the functional reserves of the body, which was manifested by the observed alternations in the electrophysiological activity of the myocardium. The maximum heart rates in spring indicate a lower efficiency of the heart muscle and the exhaustion of the chronotropic reserve. The increased values of the Rhythm indicator also point to a greater tension in the regulatory system in the cold seasons. At the end of winter and in spring, the myocardial activity in students of Nizhnevartovsk State University reached the upper limit of the physiological norm and their functional reserves were reduced.
INTER-GENDER FEATURES OF HEMODYNAMICS RHYTHMS IN NORTHERNERS WITH IMPAIRED VEGETATIVE REGULATION OF ARTERIAL PRESSURE
Authors: Surinov D. V. , Ragozin O. N. , Shalamova Ye. Yu. , Shevnin I. A.
Published: June 2020

Patients should be examined for blood pressure regulation disorders starting from a young age though adolescence and young adulthood. In this aspect, it is necessary to pay attention to neurocirculatory dystonia, as a phenomenon of impaired adaptation to changing environmental and internal conditions in which the neurohumoral regulation of various body systems, including cardiovascular, can be violated. The aim of this work was to study the inter-gender characteristics of blood pressure rhythms and heart rate in patients with hypertensive neurocirculatory dystonia living in the northern region. Wavelet analysis was used to test the hypothesis of numerous cyclicities. In patients with neurocirculatory dystonia, especially in women, the circadian structure of hemodynamic rhythms was observed to decay with an increased average daily value. The violation of vegetative regulation of arterial pressure rhythms was present in the examined northerners in the form of mesor, hyper-amplitude and ultradian desynchronosis.
SEX AND AGE CHARACTERISTICS OF DAILY ACTIVITYOF DISTANCE LEARNING STUDENTS IN NORTHERN CLIMATE
Authors: Ragozin O. N. , Shalamova Ye. Yu. , Ilyushchenko N. A. , Ragozina O. V. , Shevnin I. A. , Surinov D. V.
Published: June 2020

The purpose of the work is to study the time preferences of students performing daily tasks during distance learning and to determine if such preferences depend on sex and the year of study. In the absence of social regulation, the daytime and nighttime activity of students corresponded to the distribution of chronotypesthat typifies a northern region, with arrhythmic and evening types prevailingbut the morning biorhythmic stereotype having a minimal representation. With no ‘master timer’ in distance learning, students demonstrated pronounced sex differences in the daily dynamics of performance. Young femaleshad maximum performanceduring the day and minimum performanceat night, which corresponds to the most common type. Young males were observed to have several ascents in their performance during the 24-hour period. First-year and second-year students’ learning behavior was less synchronized with the day-night cycle. The wavelet analysis found insignificant four to five hourrhythmic fluctuations thatoccurred in the evening hours, during the period of students’ high educational performance.
STRATEGI DAN PENGENDALIAN KEPEMIMPINAN MADRASAH DALAM MENINGKATKAN MUTU PENDIDIKAN DI MAN 1 YOGYAKARTA
Authors: Rohman
Published: June 2020

Abstract: This study aims to show the application of the strategy and Madrasah leadership management towards quality improvement of education. The location of the study was conducted at Madrasah Aliyah Negeri 1 Yogyakarta (MAN 1 Yogyakarta). This type of research is a qualitative descriptive and data collection method is done by non-participant observation, in-depth interviews, and documentation. The result shown that the head of madrasah had applied strategic steps towards quality improvement of education. The priority in teachers’ training to improve their skill and learning process among students in three domains; academic, tahfidz and research. In optimizing these steps madrasah collaborates with education stakeholders, universities, training centers, academics and the community to provide guidance and assistance in improving the learning process in the internal madrasah. Besides the head of the madrasah manage activities by distributing responsibilities to each field in the madrasah organization. In addition, the relationship between the headmaster and its member are built through an intensive dialogical approach and open communication with the aim that works can be carried out together in order to improve the quality of education.

Keywords: Strategy, Management, Quality of Education, Madrasah

 

Abstrak: Penelitian ini bertujuan untuk memperlihatkan penerapan strategi dan pengendalian kepemimpinan Madrasah dalam rangka meningkatkan mutu pendidikan. Lokasi penelitian dilakukan di Madrasah Aliyah Negeri 1 Yogyakarta (MAN 1 Yogyakarta). Jenis penelitian ini adalah deskriptif kualitatif dan metode pengumpulan data dilakukan dengan observasi non partisipan, wawancara mendalam, dan dokumentasi. Hasil penelitian menunjukkan bahwa langkah-langkah strategis yang dilakukan kepala madrasah dalam meningkatkan mutu pendidikan berupa prioritas pada kegiatan pelatihan terhadap guru untuk meningkatkan skil mereka, dan prioritas peningkatan proses pembelajaran di kalangan siswa dalam tiga ranah yaitu akademis, tahfidz, dan riset. Dalam optimalisasi langkah-langkah tersebut pihak madrasah melakukan kerja sama dengan para stakeholders pendidikan, yakni perguruan tinggi, balai pelatihan, akademisi dan masyarakat guna memberi bimbingan dan pendampingan dalam meningkatkan proses pembelajaran di internal madrasah. Sementara pengendalian yang dilakukan kepala madrasah terhadap aktivitas kerja dengan cara mendistribusikan tanggung jawab terhadap masing-masing bidang dalam organisasi madrasah. Di samping itu hubungan kepala madrasah dengan bawahan dibangun dengan pendekatan dialogis dan keterbukaan komunikasi yang intensif dengan tujuan agar aktivitas kerja dapat dilakukan secara bersama-sama dalam rangka meningkatkan mutu pendidikan.

 Kata Kunci: Strategi, Pengendalian, Kepemimpinan, Mutu Pendidikan, Madrasah.
Linking Teacher-Student Relationship to Academic Achievement of Senior High School Students
Authors: Mensah Bismark , Eric Koomson
Published: June 2020

Students’ level of academic engagement and achievement at any level of education is partly knit to the kind of relationships that exist between them and their teachers. The study examined the impact of teacher-student relationship on academic achievement of students in Senior High Schools in Winneba, Ghana. Eighty students were conveniently sampled from two strata whiles data was qualitatively collected using semi-structured interview guide and analyzed thematically. The study uses the four clusters of teacher-student relationship as a framework to discuss the types of relationships that exist in Ghanaian Senior High Schools. The study revealed that connectedness, dependent, peaceful and conflicting teacher-student relationships prevail in Senior High Schools. However, administrative restrictions, and certain attitudes of teachers and students impede the development of effective teacher-student relationship. Whereas positive relationships create environments that augment academic achievement, threatening relationships stifle academic achievement. Teachers should deliberately express concerns both about students’ academic and non-academic life, as this makes the latter feel accepted and motivated to improve academic work.
lugar dos camponeses na estrutura de classes
Authors: Jollivet Marcel
Published: June 2020

Sem resumo.
Natureza e contradições da reanimação econômica de 1978/79
Authors: Souza Nilson Araújo de
Published: June 2020

Sem resumo.
Aspectos contemporâneos da questão indígena
Authors: Ribeiro Gustavo Lins
Published: June 2020

Sem resumo.
método histórico em etnologia
Authors: Rodrigues Gilda de Castro
Published: June 2020

Sem resumo.
Karl Popper
Authors: Melo Josemir Camilo de
Published: June 2020

Sem resumo.
A Religious Right to Discriminate
Authors: Gasper Travis
Published: June 2020

The Supreme Court in its 2014 decision in Burwell v. Hobby Lobby broadly expanded so-called religious freedom protections in the Religious Freedom Restoration Act (“RFRA”) by striking down a provision of the Affordable Care Act requiring employers to provide health insurance coverage for certain methods of contraception. In doing so, the Court opened the floodgates for employers to claim an exemption based upon any “sincerely held” religious belief. Without inquiry into the sincerity of that belief, businesses and corporations are free to adopt or assert beliefs that could lead to increased discrimination against employees. This is especially troublesome for marginalized groups like the LGBT community, which is already on the receiving end of discrimination under the pretext of religious exemptions. To correct any future misuse of these exemptions, Congress should amend RFRA to permit courts to assess the belief being asserted and contrast it with the potential harm if an exemption is allowed. The purpose of RFRA is to ease the burden faced by people of faith forced to go against their religious beliefs if they obey a certain statute. Easing this burden should focus on heady moral dilemmas, not mere inconveniences. Amending RFRA can ensure it maintains its initial purpose of protecting religious freedom, while not being used as a tool to perpetuate discrimination.
Brookshire Brothers v. Aldridge
Authors: Johnson Shawn A.
Published: June 2020

In July 2014, the Texas Supreme Court issued a new framework for analyzing and remedying the destruction of evidence, holding that spoliation jury instructions are warranted only when a trial court finds that a party acted with the specific intent to conceal discoverable evidence or that a party’s negligent destruction wholly prevented another from presenting a claim or defense. The Court addressed whether the trial court abused its discretion in submitting a spoliation instruction in a slip-and-fall case in which the defendant premises owner retained only eight minutes of video of the plaintiff’s fall and allowed the remaining footage to erase automatically. Although the Court recognized that a party’s willful blindness is sufficient to satisfy the intent requirement, according to critics, the Court’s application of the rule raises questions about the actions constituting willful blindness in the spoliation context and will likely invite parties to freely destroy relevant evidence without fearing a spoliation instruction or other harsh sanction. Although a thorough analysis of Texas spoliation law shows that the Brookshire framework largely follows the Trevino test previously used by a majority of Texas courts, the Court’s application of the framework indicates that spoliation instructions will now be nearly impossible for litigants to obtain.
Usando jogos de empresas para realizar pesquisas científicas
Authors: Pusanovsky de Barros Felipe , Carino Bouzada Marco Aurélio
Published: June 2020

This work aims to demonstrate the feasibility of using the results of applications of a game of companies - BR-Log - for purposes of scientific research, through an example that statistically tests the relationships among the following variables that involve operations and Logistics activities : Financial results, Market share and Inventory levels.
An analysis of association FGB and eNOS3 genes polymorphisms with intracranial hemorrhagic and atherothrombotiс ischemic stroke
Authors: Tsymbaliuk Vitalii , Vasylieva Iryna , Kostiuk Mykhaylo , Chopyk Natalia , Oleksenko Natalia , Galanta Olena , Tsiubko Olha , Makarova Tetiana , Dmytrenko Anzhela , Shuba Iryna
Published: June 2020

European Stroke Organisation (ESO) in cooperation with the
Stroke Alliance for Europe (SAFE) prepared a 2018 – 2030
European Stroke Action Plan. One of priority items of this plan
is taking to account human polygenetic risk profiles. NO-synthase3 (eNOS3) and beta-fibrinogen (FGB) polymorphisms are
clinically significant for cardiovascular diseases and ethnically
different.
Objective: to estimate the association оf polymorphisms Т-786С,
G894T 4b/4a of eNOS3 gene and С-148Т polymorphism of FGB
gene with a risk of ischemic atherothrombotiс stroke and intracranial hemorrhagic stroke of Ukrainian people.
Materials and methods. 102 patients with atherothrombotiс
ischemic stroke, 56 patients with intracranial hemorrhagic stroke
and 102 healthy control subjects were included in the study. Single
nucleotide polymorphisms were detected by polymerase chain
reaction followed by restrictases digestion and VNTR polymorphism gene was determined by allele-specific PCR method.
Results. The study revealed association of C-148T polymorphism eNOS3 gene in dominant (OR = 2,276; 95 % CI:1,298–
4,152) and multiplicative (OR = 2,322; 95 % CI:1,322–4,080)
models of analysis with a risk of ischemic atherothrombotiс
stroke. Intracranial hemorrhagic stroke manifestation associated
with VNTR 4b/4a of eNOS3 gene polymorphism in codominant
інтракраніального геморагічного інсульту, як показали кодомінантна (OR=2,509; 95 % CI:1,049-4,080), домінантна (OR = 2,977; 95 %
CI:1,344–6,596) та мультиплікативна (OR=3,037; 95 % CI:1,529–6,030)
моделі обрахунку. Комбінація генотипів 894GТ та 4b/4a гена eNOS3
із генотипом -148СТ гена FGB збільшувала, а комбінація генотипу -148СС гена FGB із генотипом -786СС гена eNOS3 зменшувала
ризик розвитку ішемічного атеротромботичного інсульту.
Висновки. Генетичне дослідження до маніфестації хвороби, особливо при спадковому обтяженні, може стати суттєвим інструментом
у розробці індивідуальних профілактичних заходів, направлених на
попередження розвитку гострих порушень мозкового кровообігу.
Ключові слова: поліморфізм, бета фібриноген, NO-синтаза 3,
ішемічний інсульт, геморагічний інсульт.
Для цитування: Цимбалюк ВІ, Васильєва ІГ, Костюк МР,
Чопик НГ, Галанта ОС, Цюбко ОІ, Олексенко НП, Дмитренко АБ,
Макарова ТА, Шуба ІМ. Аналіз асоціації поліморфізмів генів FGB та
eNOS3 із ризиком розвитку інтракраніального геморагічного
та атеротромботичного ішемічного інсультів. Журнал Національної академії медичних наук України. 2019;25(4):389–96.
Predicting The Cleavage Sites of Multiple Proteases Families on Rice Alpha Amylase Isozyme 3D Sequences
Authors: Sinaga Ayu Oshin Yap , Marpaung David Septian Sumanto
Published: June 2020

Proteases is a proteolytic enzyme that often determined the crucial process in degradation pathway occurred in all of organisms. Prediction of novel protease is important action to design the protease inhibitor.  In the secretion of rice αAmy3 protein in outside cells will be followed by secretion of recombinant protein target and proteolytic enzymes together, which means potentially also degraded the recombinant protein target In this study, the proteases was detected in rice αAMY 3D protein sequences. Our study resulted the 3 major proteases appeared in rice αAMY 3D protein sequences, they were cysteine proteases, serine proteases and metalloproteases. Based on the literature, such proteases also appeared in rice suspension cells. Design the inhibitor for such proteases will be suggested for reduction of proteases level.
Pengaruh Serangan Hama Penggerek Batang dan Penyakit Tungro terhadap Produktivitas Sembilan Varietas Padi di Lokapaksa, Bali
Authors: Suarsana Made , Parmila Putu , Wahyuni Putu Sri , Suarmika I Gusti Made
Published: June 2020

Penelitian ditujukan  pengujian varietas tanaman padi (Oryza sativa L.) terhadap serangan serangan hama penggerek batang dan penyakit tungro. Penelitian dilaksanakan tanggal 4 September sampai dengan 12 Desember 2019, di Laboratorium Peramalan Hama Penyakit (LPHP) Tangguwisia, di Subak Umadesa, Desa Lokapaksa, kecamatan seririt,  kabupaten buleleng.  Percobaan diatur dalam Rancangan Acak Kelompok  (RAK). Varietas padi yang berbeda (9 jenis)  ditetapkan sebagai perlakuan.  Tiap varietas yang diuji diulang sebanyak 3 kali sehingga pada pengujian ini terdapat 27 unit perlakuan dengan jenis varietas padi yang digunakan  sebagai  berikut: PB 64, Mikongga, Sentani, Ciherang, Inpari 30, Tropiko, Cigeulis,  Inpari 4 dan Cibogo.    Hasil pengamaan dan analisis menunnjukkan bahwa:  1. Organisme Pengganggu Tumbuhan (OPT) yang menyerang: Penyakit tungro dan hama penggerek batang; 2. Serangan penyakit tungro sangat rendah dan berbeda tidak nyata, sehingga tingkat ketahanan varietas yang diuji tidak dapat ditentukan. Tetapi varietas Mikongga paling tahan dibandingkan dengan varietas lainnya; 3. Serangan hama penggerek batang berbeda tidak nyata. Tingkat ketahanan varietas terhadap hama penggerek batang belum bisa ditentukan karena serangan masih dibawah ambang batas ekonomis (<10%); dan 4. Produksi yang diperoleh berbeda nyata antar varietas yang diuji. Produksi tertinggi terdapat pada varietas Ciherang, yaitu 11,41 ton/ha dan terendah pada varietas Cigeulis yaitu 9,52 ton/ha.
LA COMMEDIA DELL’ARTE Y BENAVENTE
Authors: Dittami Mauro
Published: June 2020

Sin información.
The Pseudamnicola spp. from Greece (Gastropoda: Hydrobiidae) with the description of four new species
Authors: Glöer Peter , Reuselaars Robert
Published: June 2020

Four species of the genus Pseudamnicola (Gastropoda: Hydrobiidae Stimpson, 1865), i.e. P. stasimoensis n. sp., P. lesbosensis n. sp., P. samosensis n. sp. and P. skalaensis n. sp are described as new to science. The type localities of 13 Pseudamnicola spp. and 1 subspecies hitherto known from Greece, including the Greek part of Cyprus, are presented on a map.
Status of Human Trafficking In South Wollo Zone, Amhara Regional State, Ethiopia: Implication for Counseling
Authors: Bezabih Mezgebu Bayu
Published: June 2020

The main purpose of this study was to examine situations of human trafficking with particular reference to South Wollo zone, Amhara regional state. Crosse sectional research design was applied and 40 Participants were took part in the study using availability sampling technique .This means those who were available at agar Ethiopia refugee’s camp during the time of data collection were inculcated into the study. The required data was collected through questionnaire and interview and then data was analyzed by using both quantitative methods such as one sample t-test and percentage as well as qualitative methods like thematic analysis. The finding of this study in on one sample t- test revealed that, the status of human trafficking, in the sample zone is high; there is increment of migration of Amhara dwellers from their native area to Areb countries. The root causes for the outbreak of human trafficking is linked with economic reason, be fool of brokers, inappropriate contestation among parents who live in the same geographical area. In line with the consequences of human trafficking, the trafficked have encountered different challenges such as exploitation of money for brokers, rape by brokers as well as paymasters as well their relatives and assassination too. Among these, rape is the most common one that the majority of trafficked are faced.
Internal Quality Assurance Model at Samarinda Midwifery Academy
Authors: Nurachma Evy , Subagiyo Lambang , Johansyah
Published: June 2020

The objectives to be achieved through this research are describe the Quality Assurance Model, Formulate the Quality Assurance Model, Describe the inhibiting factors and solution of the Quality assurance system at the Husada Flower Midwifery Academy, the Mahakam Pearl Midwifery Academy and the East Kalimantan Health Polytechnic. This study uses a qualitative approach to the type. Data collection techniques are carried out through in-depth interviews, participant observation and documentation. Establish procedures for preparation of implementation and required resources. Prepare human resources through the process of training, workshops and discussions. Samarinda Mahakam Pearl Midwifery Academy Samarinda. Conducted based on: Academic documents: quality standards that have been set. Quality document: as an instrument to achieve predetermined standards. Poltekkes Kemenkes East Kalimantan, The implementation of improving the quality assurance system is guided by: quality assurance principles oriented to inputs, processes and outputs. Formulation of Quality Assurance, preparation of quality improvement strategy plans is carried out systematically and structured in each midwifery academy which is oriented towards improving the quality of inputs, processes and outputs, with different strategies. Inhibiting factors and quality assurance system solutions implemented by carrying out: self-evaluation, internal academic quality audits, solutions carried out to determine the achievement of quality standards that have been set and evaluation findings used as material to improve the quality assurance improvement, which is planned, implemented and evaluated carried out implementation control and improvement in accordance with midwifery vocational education standards properly.
Üniversite Öğrencilerinin Yaratıcılık ile Duygu Yönetim Düzeyleri Arasındaki İlişkinin İncelenmesi
Authors: KARAOĞLU Barış , PEPE Osman
Published: June 2020

Bu araştırmanın amacı, üniversite öğrencilerinin yaratıcılık düzeyleri ile duygu yönetim düzeyleri arasındaki ilişkinin tespit edilmesidir. Araştırmaya Bingöl Üniversitesi bünyesinde bulunan Beden Eğitimi ve Spor Yüksekokulu’nda beden eğitimi ve spor öğretmenliği bölümünde bulunan tesadüfi yöntemle seçilmiş 154 öğrenci katılmıştır. Araştırmada veri toplama araçları olarak; Raudsepp (1977) tarafından geliştirilen ve Çoban (1999) tarafından Türkçe’ye uyarlanan yaratıcılık ölçeği, Çeçen (2006) tarafından geliştirilen duyguları yönetme becerileri ve kişisel bilgi formu kullanılmıştır. Araştırmada elde edilen veriler bilgisayar ortamında analiz edilmiştir. Kişisel bilgi formu, yaratıcılık ve duygu yönetim düzeyleri ölçeğinden elde edilen veriler analizleri bilgisayar ortamında yapılmıştır.
Sonuç olarak, üniversite öğrencilerinin yaratıcılık düzeylerinin ortalamanın altında, duyguları yönetme becerileri ölçeği alt başlıklarının ve toplam puanın ortalamanın üstünde olduğu tespit edilmiştir. Ayrıca, yaratıcılık düzeyleri ile duyguları yönetme becerileri alt başlıklarından başa çıkma arasında pozitif yönde düşük düzeyde ilişki tespit edilmiştir. Bu durumun, çalışmamıza katılan öğrencilerinin sportif geçmişleri sayesinde kazandıkları tecrübelerle, bedensel tepkileri kontrol, sinir ile baş edebilmeleri açısından, duygularını doğru bir şekilde düzenleyebilmeleri ve karşılaştıkları sıkıntıların da çözümünde başa çıkma becerilerini bu sportif tecrübelerin gelişmiş olmasından kaynaklandığı düşünülmektedir.
DESAFIO E PERSPECTIVAS NO PROCESSO DE ENSINO DO ESTUDANTE DA EJA
Authors: Aparecida de Oliveira Rejane , Luiz da Silva Walto
Published: June 2020

Este artigo tem como objetivo abordar e analisar quais são os desafios encontrados no processo de ensino aprendizagem do  studante da EJA, onde o aluno em qualquer modalidade de ensino, nem sempre vai à escola para cumprir com uma obrigação, mas  im para agregar conhecimentos para sua vida profissional e em especial estes estudantes. Por estarem vários anos fora da escola já  êm com um comprometimento maior, porém o desafio quanto à aprendizagem é muito grande. O percurso metodológico constou  e uma revisão bibliográfica sobre o tema, a partir de consultas em livros, revistas e artigos científicos, com ênfase na discussão sobre   educação e a responsabilidade da escola no aprendizado dos jovens adultos.
A new species of the Asian leaf litter toad genus Leptobrachella (Amphibia, Anura, Megophryidae) from southwest China
Authors: Li Shi-Ze , Liu Jing , Wei Gang , Wang Bin
Published: June 2020

A new species of the Asian leaf litter toad genusLeptobrachellafrom Guizhou Province, China is described based on molecular phylogenetic analyses, morphological comparisons, and bioacoustics data. Phylogenetic analyses based on the mitochondrial 16S rRNA gene sequences supported the new species as an independent clade nested into theLeptobrachellaclade and sister toL. bijie. The new species could be distinguished from its congeners by a combination of the following characters: small body size (SVL 30.8–33.4 mm in seven adult males, and 34.2 mm in one adult female); dorsal skin shagreened, some of the granules forming longitudinal short skin ridges; tympanum distinctly discernible, slightly concave; internasal distance longer than interorbital distance; supra-axillary, femoral, pectoral and ventrolateral glands distinctly visible; absence of webbing and lateral fringes on fingers; toes with rudimentary webbing and shallow lateral fringes, relative finger lengths II < IV < I < III; heels overlapped when thighs are positioned at right angles to the body; and tibia-tarsal articulation reaches the tympanum.
Two Paradoxostomatidae (Ostracoda) species from South Korea with a key to genera of the family
Authors: Yoo Hyunsu , Thi Van Anh Le , Karanovic Ivana
Published: June 2020

Cytherois gajinensissp. nov.is described andViolacytherois sargassicola(Hiruta, 1976) is redescribed. The species have been collected from littoral and interstitial waters in South Korea. They belong to Cytheroisinae, one of the three Paradoxostomatidae subfamilies. Both species are the first taxonomic records of the subfamily in Korea. Taxonomic keys to the living Paradoxostomatidae genera are provided in an attempt to clarify the position of some of the currently included genera as well as a key to East Asian Cytheroisinae species in order to facilitate further biodiversity research in the region.
La mémoire du temps à venir. L’expérience de la régression
Authors: Halbout Reine-Marie
Published: June 2020

La confrontation avec l’inconscient dont Jung a témoigné dans le chapitre éponyme de son livre autobiographique Ma Vie, souvenirs, rêves et pensées, s’est déroulée dans le contexte d’un rapport au temps très particulier où présent, passé et futur s’entremêlent sans cesse. Cette expérience a été vécue dans le corps, comme c’est toujours le cas pour les patients en analyse. C’est aussi par le biais de la mémoire involontaire et du retour des sensations qu’elle occasionne que Proust s’engagera, comme Jung, sur le chemin du temps retrouvé.
Au Royaume-Uni, la résistance s’organise
Authors: MacKeith Bill
Published: June 2020

Si, ces dernières décennies, la législation britannique en matière de droits des migrant·es s’est considérablement durcie, on peut s’étonner que le nombre de places en détention, préalable à l’expulsion, ait baissé. À moins que les campagnes de dénonciation et les actions spectaculaires menées par des groupes divers mais soudés dans la lutte aient progressivement éclairé l’opinion publique sur les pratiques gouvernementales et amené le pouvoir à réduire le recours à la détention comme aux expulsions.
Je préfère vivre la guerre que de vivre dans ce camp
Authors: Galisson Maël , Bruggiamosca Claire
Published: June 2020

En février 2020, le président turc Recep Tayyip Erdogan décidait unilatéralement de suspendre l’accord UE-Turquie de 2016, qui, en quatre ans, a transformé cinq îles grecques de la mer Égée en prisons à ciel ouvert pour les exilé·es, les fameux hotspots. En 2016, le Gisti envoyait une première mission à Lesbos et à Chios pour constater les conséquences dramatiques de l’accord pour les exilé·es arrivant sur ces îles. Fin 2019, une deuxième mission, envoyée à Samos, confirmait que « l’approche hotspot », vantée par la Commission européenne comme la solution à la « crise migratoire », a bien « engendré un monstre »
Les conditions changent, le rôle des chercheurs demeure : les think tanks au temps de la donnée
Authors: Boniface Pascal
Published: June 2020

Pour les think tanks et les think tankers , les data , notamment celles que l’on qualifie de big , ont fait émerger de nouveaux défis, auxquels il est nécessaire de rapidement s’adapter. Ainsi ces données peuvent-elles être vues comme un assistant performant, qui regroupe les informations plus vite que tout être humain, à la fois comme base d’une analyse géopolitique, mais aussi pour étendre son réseau. L’abondance de ces données ne doit toutefois pas modifier la mission d’un think tank , qui est de rendre le monde dans lequel nous vivons plus intelligible, tout en conservant son indépendance intellectuelle.
Les « biographies » d’une icône volante et le statut de quelques récits dans une région balkanique
Authors: Valtchinova Galia
Published: June 2020

L’article est consacré à l’usage de l’icône orthodoxe en tant que support identitaire, par le prisme de quelques récits autour d’une icône réputée à miracles : l’icône « volante » du village de Konče, en République de Macédoine du Nord. L’analyse met en œuvre les notions d’agentivité et de biographie d’image, saisies à travers des récits. La reconstitution de la « biographie » de l’icône‑qui‑vole en question à travers des récits livrés par divers interlocuteurs, dans une succession d’études sur le terrain, est au cœur de l’article. Une attention particulière est accordée au statut des récits au regard des différents acteurs locaux qui les ont produits lors de mon entrée sur le terrain et à chaque « retour », sur plus d’une décennie. Entre la voyante octogénaire, ses descendants et proches, les femmes d’un cercle orthodoxe qu’elle a animé, des habitants anonymes de deux villages, un homme d’Église et les folkloristes locaux, les récits concernant cette icône ne cessent d’être réélaborés et requalifiés, changeant de contenu comme de statut. La partie conclusive est dédiée au décryptage de processus sociopolitiques plus vastes qui se dessinent en filigrane et dont l’identification permet de comprendre la portée de ces récits comme support d’une identité complexe et fragile qui s’est construite autour d’une série d’oppositions.
Performativité des genres oraux dans la ville de Bobo‑Dioulasso lors de l’insurrection d’octobre 2014 au Burkina Faso
Authors: Sanou Alain
Published: June 2020

L’incendie de la mairie centrale de la ville de Bobo‑Dioulasso reste la marque visible des journées insurrectionnelles d’octobre 2014, comme ce fut le cas de l’Assemblée nationale pour la ville de Ouagadougou, la capitale. Les autorités municipales, depuis leur installation en février 2001, sont l’objet d’une vive contestation des Bobolais et plus particulièrement des autochtones bobo à cause de la gestion controversée de la question foncière. Cet article, résultat d’une enquête sur les genres oraux dans la ville de Bobo‑Dioulasso avant et après l’insurrection d’octobre 2014, montrera que, depuis l’an 2000, certains genres oraux bobo ont été le réceptacle de cette contestation sociale. Au fil des ans, en lien avec le contexte caractérisé par une situation conflictuelle, sont apparus des chansons, des contes et des récits oraux, qui exprimaient une révolte et par la suite, appelaient ouvertement au renversement du régime de Blaise Compaoré. La concomitance de cette production orale qui s’est créée au rythme des crises sociales ayant abouti à l’insurrection permet de s’interroger sur les liens entre la parole et l’action à partir du point de vue autochtone, c’est‑à‑dire celui d’un groupe social qui s’est retrouvé dans une situation de « subalterne ». L’efficacité de cette parole du fait même des circonstances de sa production devait produire des effets car elle relevait désormais du registre de la malédiction. L’article explore les conditions dans lesquelles cette parole de subalterne exprime sa défiance du pouvoir par la mutation d’une parole patrimoniale vers une parole qui en appelle à des actes.
« Džijás dur i mérepén » : « Il y a eu un meurtre ». Présentation d’une version manouche du conte‑type La Bête à sept têtes (T. 300) recueillie en 2018 en Creuse
Authors: Bonnemason Bénédicte , Cavaillé Jean-Pierre
Published: June 2020

L’article que nous proposons est consacré à un conte récemment collecté en Limousin (2018), en langue romani (dialecte sinto/manouche), rattachable, selon la classification internationale, au conte‑type 300 – The Dragon Slayer et introduit par le T. 315 – The Faithless Sister (respectivement La Bête à sept têtes et La Sœur infidèle dans le catalogue français). Outre la description des conditions de la collecte, la transcription en romani et la traduction en français du conte, nous nous proposons de le confronter à une autre version du T. 300 recueillie dans les années 1960, en Auvergne, dans le même dialecte et dans les mêmes familles, par Joseph Valet, et de le replacer dans le contexte particulier des trois recueils de contes manouches injustement méconnus de Valet, ainsi que dans le contexte général des multiples versions existantes en France et en Europe de ce conte‑type (la version recueillie ayant très probablement été élaborée en Alsace et en tout cas dans un environnement germanique). À travers et au‑delà de la question strictement linguistique, nous nous interrogerons sur la spécificité de l’appropriation tsigane de ce conte.
Contribution des pratiques plurilingues à la poétique d’une légende locale dans un bar de la région d’Iringa en Tanzanie
Authors: Gernez Nathaniel
Published: June 2020

Rassemblés autour d’un verre d’alcool artisanal, des hommes du village de Lulanzi, dans la région d’Iringa en Tanzanie, échangent sur les pouvoirs destructeurs d’un oiseau qui ravage les champs et défend son nid contre toute intrusion. Dans cet article, je propose d’interroger la contribution des pratiques plurilingues à la poétique de cette légende locale. En suivant Jakobson sur sa définition de la poétique, il s’agit de prendre en considération le choix des mots, des assonances, des changements de rythmes et de prosodie. En contexte plurilingue, ces variations de métrique se manifestent aussi par des changements de langues. L’interaction analysée ici permettra de voir comment l’énonciateur principal joue sur les langues et les rythmes pour créer un contraste, renforcé par la gestuelle et les expressions faciales, entre des moments où l’oiseau guette et se prépare et des moments où il attaque soudainement. Ce contexte particulier où les pratiques plurilingues ne sont motivées ni par leur indexicalité, ni par l’établissement d’une relation d’autorité ou de solidarité, sera également propice à une réflexion sur la pertinence des outils conceptuels comme le code‑switching ou la notion de translanguaging.
L’orientation scolaire sous l’emprise des rapports sociaux de sexe. La situation dans l’enseignement postsecondaire au Québec
Authors: Doray Pierre , Lépine Alexandre , Bilodeau Jaunathan
Published: June 2020

L’orientation scolaire et professionnelle est un processus qui se trouve à l’intersection de l’action des systèmes éducatifs et des dispositions et attributs sociaux et culturels des élèves et des étudiant·e·s. Observée depuis l’école, l’orientation prend la forme d’avis institutionnels quant à la poursuite des études ou d’un tri des demandes entre les filières, les programmes, les voies ou les ordres d’enseignement. Examinée par le biais des élèves, l’orientation devient un processus de choix entre des programmes et aussi entre des choix professionnels. Parmi les facteurs lourds qui modulent le tri comme le choix d’études, nous retrouvons les rapports sociaux de sexe. Le présent article s’intéresse à l’effet de ces derniers sur l’accès et sur la poursuite des études des filles qui ont choisi d’étudier dans des programmes traditionnellement composés d’une majorité de garçons, en combinant des analyses quantitatives et qualitatives. Les premières soulignent le risque élevé des départs des filles inscrites dans ces programmes. Les analyses qualitatives précisent les mécanismes de ces départs, soit les motifs d’entrée dans ces programmes, les relations sexuées au cours de l’expérience scolaire et des éléments implicites ou cachés du curriculum.
Assignations ordinaires de genre dans les métiers de la petite enfance
Authors: Sophie Devineau , François Féliu , Sandrine Valentin , Bernard Clémence
Published: June 2020

L’analyse d’une soixantaine d’entretiens biographiques menés pendant trois ans auprès d’hommes travaillant en crèche, en école maternelle ou comme assistants maternels met à jour les processus de ré-assignation de genre en dépit d’orientations masculines dérogeant initialement aux normes de la virilité. Loin des objectifs européens de 20 % d’hommes dans ce secteur, et dix ans après les premières études en France (Murcier, 2005 ; Jaboin, 2010), ces contextes relèvent encore d’une pseudo-mixité professionnelle qui favorisent une reproduction des rapports sociaux de sexe dans l’exercice ordinaire des métiers. En dépit des bonnes volontés, le temps de la formation puis de l’entrée dans les collectifs de travail est aussi celui des réassignations de genre. Les relations de travail vont encore se régler sur la complémentarité des sexes. En outre, les diverses structures organisent une véritable aspiration vers le haut des hommes qui deviennent parfois directeurs dès la première année de fonction.
Galunisertib enhances chimeric antigen receptor-modified T cell function
Authors: Wang Zhixiong , Liu Qian , Risu Na , Fu Jiayu , Zou Yan , Tang Jiaxing , Li Long , Liu Hui , Zhou Guomin , Zhu Xuekai
Published: June 2020

Chimeric antigen receptor (CAR) T cell therapy still faces the challenge of immunosuppression when treating solid tumors. TGF-β is one of the critical factors in the tumor microenvironment to help tumors escape surveillance by the immune system. Here we tried using the combination of a small molecule inhibitor of TGF-β receptor I, Galunisertib, and CAR T cells to explore whether Galunisertib could enhance CAR T cell function against solid tumor cells. In vitro experiments showed Galunisertib could significantly enhance the specific cytotoxicity of both CD133- and HER2-specific CAR T cells. However, Galunisertib had no direct killing effect on target cells. Galunisertib significantly increased the cytokine secretion of CAR T cells and T cells that do not express CAR (Nontransfected T cells). Galunisertib did not affect the proliferation of T cells, the antigen expression on target cells and CD69 on CAR T cells. We found that TGF-β was secreted by T cells themselves upon activation, and Galunisertib could reduce TGF-β signaling in CAR T cells. Our findings can provide the basis for further preclinical and clinical studies of the combination of Galunisertib and CAR T cells in the treatment of solid tumors.
Neural stem cell conditioned medium alleviates Aβ25-35 damage to SH-SY5Y cells through the PCMT1/MST1 pathway
Authors: Jia Guoyong , Yang Hongna , Diao Zengyan , Liu Ying , Sun Congcong
Published: June 2020

Alzheimer’s disease (AD) is a progressive, neurodegenerative disease. Accumulating evidence suggests that protein isoaspartate methyltransferase 1 (PCMT1) is highly expressed in brain tissue (substantia nigra, blue plaque, paraventricular nucleus). In this study, we investigated the effect of neural stem cell conditioned medium alleviates Aβ25-35 damage to SH-SY5Y cells by PCMT1/MST1 pathway. Results demonstrated that Aβ25-35 significantly decreased the cell viability in time and dose dependent manner. However, Neural stem cell-complete medium (NSC-CPM) or NSC-CDM had inhibitory effect on toxicity when fibrillation of Aβ25-35 occurred in their presence and NSC-CDM had a better inhibitor result. An increase of the PCMT1 expression levels was found in Aβ25-35 + NSC-CDM group. sh-PCMT1 significantly reduced the PCMT1, the cell viability and inhibited the protective effect; induced apoptosis and increased the expression of p-MST1. Overexpression of PCMT1 group reversed the effect of Aβ25-35 inhibited the cell viability and Aβ25-35 induced the apoptosis. In conclusion, NSC-CDM corrects the damage of Aβ25-35 to cells by increasing PCMT1, reducing MST phosphorylation.
Introduction to the Special Issue on Stem Cells and Regenerative Medicine
Authors: Yin Qinan
Published: June 2020

The special issue “Stem Cells and Regenerative Medicine” was enthusiastically released by the editorial board of European Journal of Histochemistry on 2020. The fusion of these two topics reflected the hope and potential that advances in regenerative medicine would be the promising outcomes of the basic and translational research collected in this special issue. This issue is dedicated to identifying priories in stem cell biology and capturing the cutting-edge thinking in stem-cell based regenerative medicine
Industrial pollution and mortality from digestive cancers at the small area level in a Spanish industrialized province
Authors: Santos-Sanchez Vanessa , Córdoba-Doña Juan Antonio , García-Pérez Javier , Escolar-Pujolar Antonio , Pozzi Lucia , Ramis Rebeca
Published: June 2020

The province of Cadiz, Spain, is a highly industrialized area with numerous registered industrial plants, which has led to major concern regarding the possible influence of these facilities on the high rate of cancer-related mortality observed. Our objective was to evaluate the association between digestive cancer mortality and proximity to industrial installations in the province of Cadiz over the period 1992-2014 and to analyse this risk according to different categories of carcinogenic substances. An ecological study at the census tract level was carried out. Mortality due to digestive cancer (involving the oral cavity, pharynx, oesophagus, stomach, liver, pancreas, gallbladder, colon and rectum) was analysed. Using the spatial Besag, York and Mollié (BYM) approach, we assessed the relative risk of dying from these cancers for people living between 500 m and 5 km from industrial installations. The models were adjusted to account for socioeconomic deprivation. We detected a significant, excess risk of dying due to cancer in the following organs (expressed as relative risk with 95% confidence intervals): colon/rectum (1.13; 1.04-1.22 at 4 km), stomach (1.13; 1.00-1.29 at 2 km), liver (1.28; 1.02-1.61 at 1 km), pancreas (1.19; 1.03-1.39 at 2 km), oral and pharyngeal (1.40; 1.08-1.82 at 1 km), oesophagus (2.05; 1.18-3.56 at 500 m) and gallbladder (2.80; 1.14-6.89 at 500 m) for men; and from colorectal (1.21; 1.00-1.46 at 1 km), stomach (1.15; 1.01-1.31 at 4 km) and liver (1.58; 1.20- 2.07 at 1 km) cancers for women. The results support the hypothesis of an association between several digestive cancers and proximity to polluting industrial plants.
Pathways to urban health and well-being: measuring and modelling of community services’ in a medium size city
Authors: Vannier Clémence , Campbell Malcolm , Kingham Simon
Published: June 2020

Social and natural capital are fundamental to people’s wellbeing, often within the context of local community. Developing communities and linking people together provide benefits in terms of mental well-being, physical activity and other associated health outcomes. The research presented here was carried out in Christchurch - Ōtautahi, New Zealand, a city currently re-building, after a series of devastating earthquakes in 2010 and 2011. Poor mental health has been shown to be a significant post-earthquake problem, and social connection has been postulated as part of a solution. By curating a disparate set of community services, activities and facilities, organised into a Geographic Information Systems (GIS) database, we created i) an accessibility analysis of 11 health and well-being services, ii) a mobility scenario analysis focusing on 4 general well-being services and iii) a location-allocation model focusing on 3 primary health care and welfare location optimisation. Our results demonstrate that overall, the majority of neighbourhoods in Christchurch benefit from a high level of accessibility to almost all the services; but with an urban-rural gradient (the further away from the centre, the less services are available, as is expected). The noticeable exception to this trend, is that the more deprived eastern suburbs have poorer accessibility, suggesting social inequity in accessibility. The findings presented here show the potential of optimisation modelling and database curation for urban and community facility planning purposes.
Ocular surface squamous neoplasia: Population demographics, pathogenesis and risk factors
Authors: Hollhumer Roland , Williams Susan , Michelow Pamela
Published: June 2020

Background: Ocular surface squamous neoplasia (OSSN) is a unifying term used to describe conjunctival intra-epithelial neoplasia, squamous cell carcinoma in situ and invasive squamous cell carcinoma.Aim: The aim of this article was to describe the demographics, clinical features, pathogenesis and risk factors of OSSN.Method: A literature search was conducted using the search criteria ‘ocular surface squamous neoplasia’, ‘diagnosis’, ‘epidemiology’, ‘pathogenesis’ and ‘risk factors’.Results: Ocular surface squamous neoplasia is the most common ocular tumour, with incidence rates ranging from 0.01 to 3.4 per 100 000 persons/year. There are two main patterns  of disease presentation: older white males in temperate climates where human immunodeficiency virus (HIV) and human papilloma virus (HPV) are not associated; and a younger patient population in tropical climates where HIV and HPV are more prevalent. The pathogenesis primarily revolves around ultraviolet B exposure and HPV infection that cause genetic mutations and uncontrolled cellular proliferation, whilst HIV infection and vitamin A impair tumour surveillance mechanisms. Ocular surface squamous neoplasia is first suspected clinically before formal confirmation of the diagnosis. Morphologically, it can be divided into three groups: placoid, nodular and diffuse. Placoid lesions can further be sub-divided into gelatinous, leukoplakic and papilliform lesions. Nodular lesions have the poorest prognosis, with the highest risk of metastasis and recurrence.Conclusion: Ocular surface squamous neoplasia is a common ocular tumour associated with ultraviolet radiation, HPV and HIV infection. The pathogenesis revolves around acquired genetic mutations, unregulated cellular proliferation and impaired tumour surveillance mechanisms.