bluuebunny/crossref_metadata_2025 huggingface dataset:
Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial
Authors: Kountouras Jannis , Gavalas Emmanuel , Papaefthymiou Apostolis , Tsechelidis Ioannis , Polyzos Stergios A. , Bor Serhat , Diculescu Mircea , Jadallah Κhaled , Tadeusz Mazurek , Karakan Tarkan , Bochenek Anna , Rozciecha Jerzy , Dabrowski Piotr , Sparchez Zeno , Sezgin Orhan , Gülten Macit , Farsakh Niazy Abu , Doulberis Michael
Published: July 2020

Background and Objectives: Functional dyspepsia (FD) is one of the most common functional gastrointestinal disorders; it has a great impact on patient quality of life and is difficult to treat satisfactorily. This study evaluates the efficacy and safety of trimebutine maleate (TM) in patients with FD. Materials and Methods: A multicenter, randomized, double-blind, placebo controlled, prospective study was conducted, including 211 patients with FD. Participants were randomized to receive TM 300 mg twice per day (BID, 108 patients) or placebo BID (103 patients) for 4 weeks. The Glasgow Dyspepsia Severity Score (GDSS) was used to evaluate the relief of dyspepsia symptoms. Moreover, as a pilot secondary endpoint, a substudy (eight participants on TM and eight on placebo) was conducted in to evaluate gastric emptying (GE), estimated using a 99mTc-Tin Colloid Semi Solid Meal Scintigraphy test. Results: Of the 211 patients enrolled, 185 (87.7%) (97 (52.4%) in the TM group and 88 (47.6%) in the placebo group) completed the study and were analyzed. The groups did not differ in their demographic and medical history data. Regarding symptom relief, being the primary endpoint, a statistically significant reduction in GDSS for the TM group was revealed between the first (2-week) and final (4-week) visit (p-value = 0.02). The 99 mTc-Tin Colloid Semi Solid Meal Scintigraphy testing showed that TM significantly accelerated GE obtained at 50 min (median emptying 75.5% in the TM group vs. 66.6% in the placebo group, p = 0.036). Adverse effects of low to moderate severity were reported in 12.3% of the patients on TM. Conclusion: TM monotherapy appears to be an effective and safe approach to treating FD, although the findings presented here warrant further confirmation.
Irradiation by a Combination of Different Peak-Wavelength Ultraviolet-Light Emitting Diodes Enhances the Inactivation of Influenza A Viruses
Authors: Kojima Mizuki , Mawatari Kazuaki , Emoto Takahiro , Nishisaka-Nonaka Risa , Bui Thi Kim Ngan , Shimohata Takaaki , Uebanso Takashi , Akutagawa Masatake , Kinouchi Yohsuke , Wada Takahiro , Okamoto Masayuki , Ito Hiroshi , Tojo Kenji , Daidoji Tomo , Nakaya Takaaki , Takahashi Akira
Published: July 2020

Influenza A viruses (IAVs) pose a serious global threat to humans and their livestock. This study aimed to determine the ideal irradiation by ultraviolet-light emitting diodes (UV-LEDs) for IAV disinfection. We irradiated the IAV H1N1 subtype with 4.8 mJ/cm2 UV using eight UV-LEDs [peak wavelengths (WL) = 365, 310, 300, 290, 280, 270, and 260 nm)] or a mercury low pressure (LP)-UV lamp (Peak WL = 254 nm). Inactivation was evaluated by the infection ratio of Madin–Darby canine kidney (MDCK) cells or chicken embryonated eggs. Irradiation by the 260 nm UV-LED showed the highest inactivation among all treatments. Because the irradiation-induced inactivation effects strongly correlated with damage to viral RNA, we calculated the correlation coefficient (RAE) between the irradiant spectrum and absorption of viral RNA. The RAE scores strongly correlated with the inactivation by the UV-LEDs and LP-UV lamp. To increase the RAE score, we combined three different peak WL UV-LEDs (hybrid UV-LED). The hybrid UV-LED (RAE = 86.3) significantly inactivated both H1N1 and H6N2 subtypes to a greater extent than 260 nm (RAE = 68.6) or 270 nm (RAE = 42.2) UV-LEDs. The RAE score is an important factor for increasing the virucidal effects of UV-LED irradiation.
Diet and Lp(a): Does Dietary Change Modify Residual Cardiovascular Risk Conferred by Lp(a)?
Authors: Enkhmaa Byambaa , Petersen Kristina S. , Kris-Etherton Penny M. , Berglund Lars
Published: July 2020

Lipoprotein(a) [Lp(a)] is an independent, causal, genetically determined risk factor for cardiovascular disease (CVD). We provide an overview of current knowledge on Lp(a) and CVD risk, and the effect of pharmacological agents on Lp(a). Since evidence is accumulating that diet modulates Lp(a), the focus of this paper is on the effect of dietary intervention on Lp(a). We identified seven trials with 15 comparisons of the effect of saturated fat (SFA) replacement on Lp(a). While replacement of SFA with carbohydrate, monounsaturated fat (MUFA), or polyunsaturated fat (PUFA) consistently lowered low-density lipoprotein cholesterol (LDL-C), heterogeneity in the Lp(a) response was observed. In two trials, Lp(a) increased with carbohydrate replacement; one trial showed no effect and another showed Lp(a) lowering. MUFA replacement increased Lp(a) in three trials; three trials showed no effect and one showed lowering. PUFA or PUFA + MUFA inconsistently affected Lp(a) in four trials. Seven trials of diets with differing macronutrient compositions showed similar divergence in the effect on LDL-C and Lp(a). The identified clinical trials show diet modestly affects Lp(a) and often in the opposing direction to LDL-C. Further research is needed to understand how diet affects Lp(a) and its properties, and the lack of concordance between diet-induced LDL-C and Lp(a) changes.
Precursor Intensity-Based Label-Free Quantification Software Tools for Proteomic and Multi-Omic Analysis within the Galaxy Platform
Authors: Mehta Subina , Easterly Caleb W. , Sajulga Ray , Millikin Robert J. , Argentini Andrea , Eguinoa Ignacio , Martens Lennart , Shortreed Michael R. , Smith Lloyd M. , McGowan Thomas , Kumar Praveen , Johnson James E. , Griffin Timothy J. , Jagtap Pratik D.
Published: July 2020

For mass spectrometry-based peptide and protein quantification, label-free quantification (LFQ) based on precursor mass peak (MS1) intensities is considered reliable due to its dynamic range, reproducibility, and accuracy. LFQ enables peptide-level quantitation, which is useful in proteomics (analyzing peptides carrying post-translational modifications) and multi-omics studies such as metaproteomics (analyzing taxon-specific microbial peptides) and proteogenomics (analyzing non-canonical sequences). Bioinformatics workflows accessible via the Galaxy platform have proven useful for analysis of such complex multi-omic studies. However, workflows within the Galaxy platform have lacked well-tested LFQ tools. In this study, we have evaluated moFF and FlashLFQ, two open-source LFQ tools, and implemented them within the Galaxy platform to offer access and use via established workflows. Through rigorous testing and communication with the tool developers, we have optimized the performance of each tool. Software features evaluated include: (a) match-between-runs (MBR); (b) using multiple file-formats as input for improved quantification; (c) use of containers and/or conda packages; (d) parameters needed for analyzing large datasets; and (e) optimization and validation of software performance. This work establishes a process for software implementation, optimization, and validation, and offers access to two robust software tools for LFQ-based analysis within the Galaxy platform.
An Overview of the Dynamics of Relative Research Performance in Central-Eastern Europe Using a Ranking-Based Analysis Derived from SCImago Data
Authors: Ianoş Ioan , Petrişor Alexandru-Ionuţ
Published: July 2020

In recent times, rankings seem to play an increasingly important role, influencing the lives of individual researchers or academics and their institutions. Individual and institutional rankings used for promotion and research or academic funding seem to illustrate more and more the “publish or perish” mantra, relying sometimes almost exclusively on publications and their citations. Eastern Europe found itself part of this new world after a period of isolation, uneven for the countries within the area. The present study uses SCImago data to perform a regional analysis of individual and aggregated domains, for individual countries and the entire region, based on a novel “adjusted citation index”, in order to measure the performance and identify, using correlations with additional data and information, the mechanisms that can increase the research performance of a country. In a nutshell, the results indicate that the national research policies are responsible for performance. Adaptive research policies simulate a real performance, in comparison with more restrictive ones, which are more likely to stimulate unethical behaviors such as self-citations or citation stacking, especially when used for the assessment of researchers. The importance of the findings lies in the possibility of replicating the methodology, adapting it to different spatial scales.
Development of the Chinese Space-Based Radiometric Benchmark Mission LIBRA
Authors: Zhang Peng , Lu Naimeng , Li Chuanrong , Ding Lei , Zheng Xiaobing , Zhang Xuejun , Hu Xiuqing , Ye Xin , Ma Lingling , Xu Na , Chen Lin , Schmetz Johannes
Published: July 2020

Climate observations and their applications require measurements with high stability and low uncertainty in order to detect and assess climate variability and trends. The difficulty with space-based observations is that it is generally not possible to trace them to standard calibration references when in orbit. In order to overcome this problem, it has been proposed to deploy space-based radiometric reference systems which intercalibrate measurements from multiple satellite platforms. Such reference systems have been strongly recommended by international expert teams. This paper describes the Chinese Space-based Radiometric Benchmark (CSRB) project which has been under development since 2014. The goal of CSRB is to launch a reference-type satellite named LIBRA in around 2025. We present the roadmap for CSRB as well as requirements and specifications for LIBRA. Key technologies of the system include miniature phase-change cells providing fixed-temperature points, a cryogenic absolute radiometer, and a spontaneous parametric down-conversion detector. LIBRA will offer measurements with SI traceability for the outgoing radiation from the Earth and the incoming radiation from the Sun with high spectral resolution. The system will be realized with four payloads, i.e., the Infrared Spectrometer (IRS), the Earth-Moon Imaging Spectrometer (EMIS), the Total Solar Irradiance (TSI), and the Solar spectral Irradiance Traceable to Quantum benchmark (SITQ). An on-orbit mode for radiometric calibration traceability and a balloon-based demonstration system for LIBRA are introduced as well in the last part of this paper. As a complementary project to the Climate Absolute Radiance and Refractivity Observatory (CLARREO) and the Traceable Radiometry Underpinning Terrestrial- and Helio- Studies (TRUTHS), LIBRA is expected to join the Earth observation satellite constellation and intends to contribute to space-based climate studies via publicly available data.
Evaluation of Inter-System Bias between BDS-2 and BDS-3 Satellites and Its Impact on Precise Point Positioning
Authors: Zhao Wen , Chen Hua , Gao Yang , Jiang Weiping , Liu Xuexi
Published: July 2020

The BeiDou navigation satellite system (BDS) currently has 41 satellites in orbits and will reach its full constellation following the launch of the last BDS satellite in June 2020 to provide navigation, positioning, and timing (PNT) services for global users. In this contribution, we investigate the characteristics of inter-system bias (ISB) between BDS-2 and BDS-3 and verify whether an additional ISB parameter should be introduced for the BDS-2 and BDS-3 precise point positioning (PPP). The results reveal that because of different clock references applied for BDS-2 and BDS-3 in the International GNSS Service (IGS) precise satellites clock products and the inconsistent code hardware delays of BDS-2 and BDS-3 for some receiver types, an ISB parameter needs to be introduced for BDS-2 and BDS-3 PPP. Further, the results show that the ISB can be regarded as a constant within a day, the value of which is closely related to the receiver type. The ISB values of the stations with the same receiver type are similar to each other, but a great difference may be presented for different receiver types, up to several meters. In addition, the impact of ISB on PPP has also been studied, which demonstrates that the performance of kinematic PPP could be improved when ISB is introduced.
Synergy of High-Resolution Radar and Optical Images Satellite for Identification and Mapping of Wetland Macrophytes on the Danube Delta
Authors: Niculescu Simona , Boissonnat Jean-Baptiste , Lardeux Cédric , Roberts Dar , Hanganu Jenica , Billey Antoine , Constantinescu Adrian , Doroftei Mihai
Published: July 2020

In wetland environments, vegetation has an important role in ecological functioning. The main goal of this work was to identify an optimal combination of Sentinel-1 (S1), Sentinel-2 (S2), and Pleiades data using ground-reference data to accurately map wetland macrophytes in the Danube Delta. We tested several combinations of optical and Synthetic Aperture Radar (SAR) data rigorously at two levels. First, in order to reduce the confusion between reed (Phragmites australis (Cav.) Trin. ex Steud.) and other macrophyte communities, a time series analysis of S1 data was performed. The potential of S1 for detection of compact reed on plaur, compact reed on plaur/reed cut, open reed on plaur, pure reed, and reed on salinized soil was evaluated through time series of backscatter coefficient and coherence ratio images, calculated mainly according to the phenology of the reed. The analysis of backscattering coefficients allowed separation of reed classes that strongly overlapped. The coherence coefficient showed that C-band SAR repeat pass interferometric coherence for cut reed detection is feasible. In the second section, random forest (RF) classification was applied to the S2, Pleiades, and S1 data and in situ observations to discriminate and map reed against other aquatic macrophytes (submerged aquatic vegetation (SAV), emergent macrophytes, some floating broad-leaved and floating vegetation of delta lakes). In addition, different optical indices were included in the RF. A total of 67 classification models were made in several sensor combinations with two series of validation samples (with the reed and without reed) using both a simple and more detailed classification schema. The results showed that reed is completely discriminable compared to other macrophyte communities with all sensor combinations. In all combinations, the model-based producer’s accuracy (PA) and user’s accuracy (UA) for reed with both nomenclatures were over 90%. The diverse combinations of sensors were valuable for improving the overall classification accuracy of all of the communities of aquatic macrophytes except Myriophyllum spicatum L.
A Method for Sensor-Based Activity Recognition in Missing Data Scenario
Authors: Hossain Tahera , Ahad Md. Atiqur Rahman , Inoue Sozo
Published: July 2020

Sensor-based human activity recognition has various applications in the arena of healthcare, elderly smart-home, sports, etc. There are numerous works in this field—to recognize various human activities from sensor data. However, those works are based on data patterns that are clean data and have almost no missing data, which is a genuine concern for real-life healthcare centers. Therefore, to address this problem, we explored the sensor-based activity recognition when some partial data were lost in a random pattern. In this paper, we propose a novel method to improve activity recognition while having missing data without any data recovery. For the missing data pattern, we considered data to be missing in a random pattern, which is a realistic missing pattern for sensor data collection. Initially, we created different percentages of random missing data only in the test data, while the training was performed on good quality data. In our proposed approach, we explicitly induce different percentages of missing data randomly in the raw sensor data to train the model with missing data. Learning with missing data reinforces the model to regulate missing data during the classification of various activities that have missing data in the test module. This approach demonstrates the plausibility of the machine learning model, as it can learn and predict from an identical domain. We exploited several time-series statistical features to extricate better features in order to comprehend various human activities. We explored both support vector machine and random forest as machine learning models for activity classification. We developed a synthetic dataset to empirically evaluate the performance and show that the method can effectively improve the recognition accuracy from 80.8% to 97.5%. Afterward, we tested our approach with activities from two challenging benchmark datasets: the human activity sensing consortium (HASC) dataset and single chest-mounted accelerometer dataset. We examined the method for different missing percentages, varied window sizes, and diverse window sliding widths. Our explorations demonstrated improved recognition performances even in the presence of missing data. The achieved results provide persuasive findings on sensor-based activity recognition in the presence of missing data.
Microbe Biomass in Relation to Organic Carbon and Clay in Soil
Authors: Liddle Kaylin , McGonigle Terence , Koiter Alexander
Published: July 2020

Soil microbes are key to nutrient cycling and soil formation, yet the impact of soil properties on microbe biomass remains unclear. Using 240 soil cores of 0–15 cm depth, taken at random points across six cattle-grazed pastures on an undulating landscape, we evaluated the biomass of microbes in soil as affected by naturally occurring variation in soil organic carbon (SOC), clay content, and local topography. The study pastures varied in historic land-use for crops or forage seeding. SOC was found to be greater in topographically low areas. In contrast, clay content was not related to topography, and clay deposition possibly varies with glaciation legacy. Microbial biomass carbon (MBC) was correlated positively with SOC, increasing from 700 mg kg−1 MBC at 25 g kg−1 SOC to 2240 mg kg−1 MBC at 90 g kg−1 SOC. Most likely, SOC promotes MBC through the release of water-soluble organic carbon. However, the response of MBC to clay content was negative, decreasing from 1340 mg kg−1 MBC at 5% clay to 880 mg kg−1 MBC at 30% clay. Small voids in association with clay particles likely restrict the access of microbes to SOC. The relationship between SOC and MBC illustrates the important role of SOC for soil function, in terms of nutrient availability and development of soil structure via the contribution of microbes. Lastly, there was considerable spatial variability in MBC across the 65 ha site, highlighting the importance of land-use histories and gradients in environmental variables, to determine the biomass of microbes in soil.
QUALITY OF EDUCATION AS A CATALYST OF EFFICIENCY OF THE INNOVATION PROGRESS OF SOCIETY
Authors: Gao Weizhen
Published: July 2020

The economic and innovational development depend on the quality of human capital, which is determined by the quality of education. The quality of training of pupils and students depends not only on traditional factors (amounts of funding, composition of groups), but also on the qualification of teachers, the level of introduction of new technologies in the educational process. A significant role in increasing the competitiveness of national education systems is played by the English language, which is an imperative condition for innovative breakthroughs, scientific achievements, mastery of new technologies. There is a redistribution of spheres of influence in the field of secondary and higher education at the global level, where the countries of the East Asian region are at the forefront. Attention to postdoctoral training as a prerequisite for improving the efficiency of the innovation process is significantly increasing. The necessity of finding a balance in the teaching of humanities and natural sciences and engineering disciplines in order to reveal the innovative potential of societies in the conditions of rapid technological changes is substantiated.
TINGKAT SELF CARE KLIEN RAWAT JALAN DIABETES MELLITUS DI RS PKU MUHAMMADIYAH BANTUL
Authors: Nur Imallah Rosiana , Rahmawati Agustina
Published: July 2020

Diabetes mellitus (DM) merupakan penyakit kronis yang dapat mempengaruhi kondisi fisik, psikologis, sosial bahkan spiritual penderitanya. Salah satu upaya untuk dapat meminimalkan komplikasi DM adalah dengan melakukan self care DM. Penelitian ini bertujuan untuk menggambarkan tingkat kepatuhan self care pada pasien DM yang menjalani rawat jalan di RS PKU Muhamamdiyah Bantul. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan menggunakan pendekatan cross sectional. Sampel penelitian adalah 54 responden pasien rawat jalan di poliklinik penyakit dalam di RS PKU Muhammadiyah Bantul pada bulan Agustus 2019. Alat ukur yang digunakan adalah kuesioner SDSCA (Summary Diabetes Self Care Activities). Sebagian besar responden memiliki nilai tinggi dalam perilaku self care (51,9%). Perlunya upaya untuk meningkatkan kepatuhan self care pada pasien DM dan perawat dapat berperan penting didalamnya.

 

Diabetes mellitus (DM) is a chronic disease that can affect the physical, psychological, social and even spiritual condition of the sufferer. One effort to minimize DM complications is by doing DM self care. This study aims to describe the level of self care adherence in DM patients undergoing outpatient care at PKU Muhammadiyah Hospital Bantul. This research is a quantitative research using a cross sectional approach. A sample of 54 respondents who were outpatients in the internal medicine clinic at PKU Muhammadiyah Hospital Bantul in August 2019. The measuring instrument used was the SDSCA (Summary Diabetes Self Care Activities) questionnaire. Self-care behavior in the majority of respondents in the high category (51.9%). The need for efforts to improve self-care compliance in DM patients and nurses can play an important role in it. The results of this study indicate that the majority of DM patient have high self-care behavior.
EDUKASI DENGAN MEDIA AUDIOVISUAL TERHADAP PERILAKU CUCI TANGAN PADA KELUARGA PASIEN RAWAT INAP
Authors: Safitri Wahyuningsih , Wihastutik Nining , Nurhidayati Anis , Nur Kusumawati Heni
Published: July 2020

Penyakit  infeksi  merupakan  penyebab  utama  tingginya  angka  kesakitan  dan  kematian  di  dunia. Upaya untuk mencegah  terjadinya  infeksi  nosokomial  adalah  dengan  menjalankan  universal precautian  yang  salah  satunya  dengan  mencuci  tangan  pada  setiap  penanganan  pasien  di  rumah  sakit. Edukasi dengan media audio visual lebih menarik dan lebih mudah dipahami dan diharapkan keluarga pasien mempunyai perilaku cuci tangan yang benar. Penelitian ini bertujuan untuk mengetahui pengaruh edukasi dengan media audiovisual terhadap perilaku cuci tangan pada keluarga pasien. Jenis penelitian yang digunakan adalah penelitian kuantitatif, menggunakan rancangan penelitian quasi eksperiment dengan Non-equivalent control group design. Populasi dalam penelitian ini adalah semua keluarga pasien sebanyak 98 orang. Pengambilan sampel dalam penelitian ini menggunakan stratified proportionate random sampling. Analisa data dalam penelitian ini menggunakan uji Mann-Whitney. Hasil penelitian menunjukkan ada pengaruh edukasi media audiovisual terhadap perilaku cuci tangan pada keluarga pasien rawat inap dengan p value 0,011. Hasil penelitian ini dapat menjadi rujukan dalam meningkatkan perilaku kesehatan melalui media audiovisual.

 

Infectious diseases are the main cause of high morbidity and mortality rates in the world. Efforts to prevent the occurrence of nosocomial infections is to carry out universal precautian, one of which is by washing hands in every handling of patients in the hospital. Education with audio visual media is more interesting and easier to understand and it is expected that the patient's family has the correct hand washing behavior. This study aims to determine the effect of education with with audio visual media on hand washing behavior in patients' families.This type of research is quantitative research, using a quasi-experimental research design with Non-equivalent control group design. The population in this study were all patients' families as many as 98 people. Sampling in this study used a stratified proportionate random sampling. Analysis of the data in this study using the Mann-Whitney test. The results showed there was an influence of  audio visual media on hand washing behavior in the families of inpatients with a p value of 0.011. The results of this study can be a reference in improving health behavior through audiovisual media.
PENGARUH ABDOMINAL MASSAGE DALAM UPAYA PENCEGAHAN KONSTIPASI PADA LANJUT USIA DI BPSTW ABIYOSO YOGYAKARTA
Authors: Anjar Rina Setyani Fransisca , Ikaristi Maria Theresia Siwi
Published: July 2020

Salah satu gangguan pola eliminasi defekasi adalah konstipasi. Dari 20 lansiadi BPSTW Abiyoso, ternyata 9 diantaranya mengungkapkan mengalami kesulitan untuk buang air besar. Tujuan penelitian ini adalah mengetahui pengaruh abdominal massage untuk mencegah konstipasi pada lansia di BPSTW Abiyoso Yogyakarta dan faktor counfounding yang mempengaruhi pola eliminasi defekasi lansia di BPSTW Abiyoso Yogyakarta. Penelitian ini menggunakan desain quasi experimental, dimana peneliti membandingkan perbedaan pola eliminasi defekasi pada kelompok kontrol dan intervensi. Sampel dalam penelitian ini sebanyak 32 responden yang dibagi menjadi dua kelompok yaitu 16 responden pada kelompok kontrol dan 16 responden pada kelompok intervensi. Hasil uji t-independen menunjukkan bahwa ada perbedaan yang signifikan score defekasi pada kelompok kontrol dan intervensi artinya ada pengaruh pemberian abdominal massage pada lansia terhadap keteraturan pola eliminasi defekasi pada lansia (p value = 0.049; ? = 0.05). Perawat dapat menggunakan abdominal massage sebagai salah satu terapi non farmakologi untuk menjaga keteraturan pola eliminasi defekasi pada lansia.

 

One disruption of the pattern of elimination of defecation is constipation. Elderly and someone who has a decreased physical ability are at risk for constipation. The purpose of this research is to know the effect of abdominal massage to prevent constipation toward elderly at BPSTW Abiyoso in Yogyakarta.  This research uses quasi experimental, which compares the differences of elimination defecation patterns between kontrol and intervention groups. The number of sampels were 32 respondents, divided into 2 groups, i.e. 16 respondents in the kontrol group and 16 respondents in the intervention group. Independent t-test results showed significant difference defecation scores between the kontrol and intervention groups, meaning that there is the effect of abdominal massage to prevent constipation towrad elderly (p value = 0.049; ? = 0.05). Confounding variables related with the pattern of elimination is physical activity.
Factors Affecting Egg Deposition of the European Mantis
Authors: Kajzer-Bonk Joanna
Published: July 2020

In this paper, we studied the egg-case (oothecae) deposition of the European mantis, Mantis religiosa (Linnaeus 1758), a predatory insect. We hypothesized that the height of ootheca deposition on a plant reflects the insolation requirements of the species, and would increase
when plant cover is denser. We found that the taller the plants nearby, the greater the height of egg deposition. Oothecae were also oviposited higher in denser vegetation. The observed behavior may ensure the proper insolation of developing offspring. To our knowledge, this is the first description
of an egg laying strategy of this species under natural conditions. This finding allows for a better understanding of habitat selection and the overall ecology of the European mantis. It may be also useful in identifying the mechanisms of the range extension of this species and is a potential
tool to effectively conserve xerothermic ootheca-laying animals. Further studies are required to assess the flexibility of this behavior under different environmental conditions.
Galectin-3 Deficiency Reduces Cardiac and Renal Antioxidant Capacity in Mice
Authors: Vučević Danijela B. , Borozan Sunčica Z. , Radenković Ana S. , Radosavljević Milica I. , Mladenović Dušan R. , Jorgačević Bojan Z. , Samardžić Janko M. , Vesković Milena N. , Vukićević Dušan V. , Radosavljević Tatjana S.
Published: July 2020

Galectin-3 (Gal-3) has increasingly been recognized as a modulator of inflammation, oxidative/nitrosative stress, fibrogenesis, and tissue remodeling. The objective of the current pilot study was to investigate the influence of Gal-3 on cardiac and renal antioxidant capacity using biochemical
and histopathological examinations. Two groups (n=7 each) of male mice were tested: 1. control (CON) group (wild type of C57BL/6 mice) and 2. GAL-3-/- group (galectin-3-/- knockout mice). After overnight fasting, mice were sacrificed by exsanguination in ketamine (100mg/kg
intraperitoneally). Then, cardiac and renal tissue samples were taken to determine the parameters of oxidative/nitrosative stress and antioxidant capacity. The levels of malondialdehyde and nitrites+nitrates was not significantly different in the GAL-3-/- group vs. the CON group.
The total superoxide dismutase activity in the renal tissue of the GAL-3-/- mice was significantly lower compared to the CON group. Cardiac and renal catalase and glutathione S-transferase activity was significantly reduced in the GAL-3-/- group vs. the CON group, respectively.
A significant decrease in glutathione level was also registered in hearts of the GAL-3-/- group vs. the CON group. Our findings indicate that Gal-3 deficiency does not lead to lipid peroxidation and nitrosative stress in cardiac and renal tissue in mice. However, the lack of this
beta-galactoside-binding lectin does reduce antioxidant capacity in both of the investigated tissues.
Light-Triggered Catalytic Performance Enhancement Using Magnetic Nanomotor Ensembles
Authors: Ji Fengtong , Wang Ben , Zhang Li
Published: July 2020

Micro/nanomachines have attracted extensive attention in the biomedical and environmental fields for realizing functionalities at small scales. However, they have been rarely investigated as active nanocatalysts. Heterogeneous nanocatalysts have exceptional reusability and recyclability, and integration with magnetic materials enables their recovery with minimum loss. Herein, we propose a model active nanocatalyst using magnetic nanomotor ensembles (MNEs) that can degrade contaminants in an aqueous solution with high catalytic performance. MNEs composed of a magnetite core coated with gold nanoparticles as the nanocatalyst can rotate under the action of a programmable external field and carry out rapid reduction of 4-nitrophenol (4-NP). The hydrogen bubbles generated in the catalytic reaction provide random perturbations for the MNEs to travel in the reaction solution, resulting in uniform processing. The reduction can be further boosted by irradiation with near-infrared (NIR) light. Magnetic field induces the rotation of the MNEs and provides microstirring in the catalysis. Light enhances the catalytic activity
via
the photothermal effect. These MNEs are also capable of moving to the targeted region through the application of a programmable magnetic field and then process the contaminant in the targeted region. We expect that such magnetic MNEs may help better in applying active heterogeneous nanocatalysts with magnetic field and light-enhanced performance in industrial applications due to their advantages of low material cost and short reaction time.
Global Incidence and Mortality Rate of COVID-19; Special Focus on Iran, Italy and China
Authors: Chaibakhsh Samira , Pourhoseingholi Asma , Vahedi Mohsen
Published: July 2020

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new coronavirus, was diagnosed in China in December 2019. Around the globe, a total of 71429 were infected up to February 17, 2020, with 98.9% of cases in China. On March 11, 2020, the World Health Organization (WHO) characterized the COVID-19 as ‘pandemic’. Rapid positive worldwide incidence was the motivation behind this study to investigate the incidence and mortality globally. Methods: We used the data published by the WHO until March 9, 2020. Non-parametric tests and change point analysis were used for inferences. Results: Change point analysis for Iran and China and the world excluding China for the first 20 days revealed around 78, 195 and 2 further new cases per day, respectively. Italy had a big jump in incidence on the 36th day. Similarly, a sharp rise of positive cases was reported for the world on the 35th day. China successfully controlled the ascending reports of incidence on the 23rd day. Mortality in China and the world were almost similar for the first 20 days. There was an ascending incidence trend with two change points in Italy (30th and 36th days) and one change point in Iran on the 17th day. Mortality in the world jumped remarkably after day 42 with an estimation of almost more than 25 deaths per day. Conclusion: The incidence of COVID-19 varied by regions; however, after March 11, it became ‘pandemic’. It was observed that after about 6 days with an emergence of sharp increase in incidences, there would be a mutation in mortality rate. On the other hand, the importance of ‘on-time’ quarantine programs in controlling this virus was confirmed.
Chorioamnionitis and Neonates; Which Strategy?
Authors: Afjeh Seyyed-Abolfazl , Sabzehei Mohammad Kazem , Mansor Ghanaie Roxana , Karimizadeh Mahdiyeh , Shamshiri Ahmad Reza , Esmaili Fatemeh
Published: July 2020

Background: Chorioamnionitis (CAM) is one of the major risk factors for neonatal early-onset sepsis (EOS). Different international guidelines have been developed for diagnosis and care of such neonates. This research aimed to evaluate our neonates and compare them with the guidelines. Methods: This prospective cohort study was conducted during five years (March 2012 to March 2017), and comprised of neonates (any gestational age) born to mothers with CAM (any criteria). The neonates’ clinical findings and interventions were collected and analyzed. Results: In total, out of 28,988 live born neonates, CAM was found in mothers of 169 neonates (1.7%). Among the studied neonates, 30.8% were born ≤34 week of gestation, 39% had birth weight <2500 g, and 58.6% were asymptomatic. Out of 99 asymptomatic neonates, 47 were observed near mothers and 52 admitted to the neonatal intensive care unit (NICU). The frequency of abnormal tests was 23.07% in asymptomatic vs. 35.7% in symptomatic neonates; three neonates developed culture positive EOS (2.75%) and 68.05% of the neonates received antibiotics. The length of stay was 2.59 ± 1.13 (median = 2.00, IQR = 1.00) days in asymptomatic vs. 15.15 ± 13.67 (median = 7.00, IQR = 15.25) days in symptomatic neonates (P<0.001). Conclusion: The use of guidelines increased the length of stay, lab tests, and antibiotics in asymptomatic and neonates with negative blood culture. In addition to the mother-neonate separation, these guidelines may increase nosocomial infection, antibiotic resistance, and costs; therefore, new guidelines are needed to be developed.
Phyllodes Tumor of the Breast during Pregnancy and Lactation; A Systematic Review
Authors: Alipour Sadaf , Eskandari Amirhossein , Johar Fatimah Mat , Furuya Shinji
Published: July 2020

Background: Phyllodes tumor (PT) is a rare tumor of the breast, which may occur during pregnancy or lactation. Several studies have reviewed and discussed PT occurring in pregnancy, gathering up to 14 patients. We performed a thorough systematic review of the literature in an attempt to find all reported cases, and identify their common characteristics. Methods: We searched Google scholar, PubMed, Ovid Medline, Scopus and ClinicalTrials.gov with several relevant combinations of keywords, looking for texts or abstracts without any date or language limitations, but using only English keywords. The existing literature only consisted of case reports and series; therefore any paper including one or several cases of PT presenting during pregnancy or breastfeeding was recognized as eligible. Articles with vague description of the tumor which made the diagnosis uncertain, and those lacking data about the tumor and management data were excluded. We contacted authors for more details in cases with incomplete information. Results: After excluding those with very deficient data, we included 37 studies, counting 43 cases. The mean age of the patients was 31 years (21-43 years). Some features were different from usual PT: bilaterality (16.2%), large size (14.2 ± 8.6 cm), rapid enlargement (79.5%), and rate of malignancy (60.5%). Conclusion: Our findings show high rates of bilaterality, large size, rapid growth, and malignant pathology in the reported gestational PTs.
SARS-CoV-2; What We Know so far
Authors: Rajani Huda Fatima , Alshaikh Fatima Ahmed , Anushiravani Amir
Published: July 2020

A recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 1100000 (April 5, 2020) individuals worldwide and is spreading rapidly. The virus is reported to be derived from bats and the infection was first reported in China. Similar to the severe acute respiratory syndrome and the Middle East respiratory syndrome coronaviruses, it is responsible for respiratory tract infection. Real time polymerase chain reaction and radiography are the two main diagnostic methods. Guidelines from the Center for Disease Control and Prevention and the World Health Organization (WHO) should be followed for diagnostic and precautionary measures. Treatment of the infection is still not available; however, antivirals are under clinical trials.
The COVID-19 Outbreak in Iran; The First Patient with a Definite Diagnosis
Authors: Ghadir Mohammadreza , Ebrazeh Ali , Khodadadi Javad , Zamanlu Masumeh , Shams Saeed , Nasiri Maryam , Koohpaei Alireza , Abbasinia Mohammad , Sharifipour Ehsan , Golzari Samad EJ
Published: July 2020

The novel coronavirus, formerly named as 2019 novel coronavirus (2019-nCov) caused a rapidly spreading epidemic of severe acute respiratory syndrome (SARS) in Wuhan, China and thereafter, progressed globally to form a pandemic of coronavirus disease 2019 (COVID-19) in numerous countries; and now confirmed cases are reported from several provinces of Iran. Now various medical centers, clinicians and researchers around the world share their data and experiences about COVID-19 in order to participate in the global attempt of controlling the pandemic. The current report investigates the clinical presentations and paraclinical findings of the first confirmed cases and mortalities in the initiation of the outbreak of COVID-19 in Iran.
Society, Socialization and Social Order through the Hindu Festivals in Nepal
Authors: Dahal Bishnu Prasad
Published: July 2020

Festivals impart entertainment in society, people participate in socialization, and festivals act as a mechanism to resolve the social tensions, conflicts, and social stress through participation of their members. It provides a platform to express, share and understand their ideas to others through interactions. In a way, it imparts societal glue because it offers people meaning and purpose for their lives, and it gives definite values and meanings. That's why people believe in religious religions offer ceremonies and festivals socialize their members with their values, and ultimately festivals, work an agency to control the behavior of people either imparting "hope" or creating by "fear." In fact, religions, rituals and festivals are practices required or expected of members of faith and usually honor the divine power (or powers) worshipped by believers; the) also remind adherents of their religious duties and responsibilities.
Results of Surgical Management of Highly Unstable Complex Distal Femur Fractures with Distal Femoral Locking Compression Plate Fixation: A Prospective Study of 58 Cases
Authors: Sharma Dr. Rajesh Kumar , Goel Dr. Rajesh
Published: July 2020

Background: The optimal treatment of complex distal femur fractures always remains challenging and controversial. The purpose of this prospective study was to evaluate the efficacy of distal femoral locking compression plate (DF-LCP) in terms of functional outcome, and union rate for highly unstable or complex distal femurfractures and to determine the influencing factors of an unfavorable outcome.
Methods: After obtaining approval from the institutional ethics committee, 58 patients with complex distal femur were managed by open reduction and internal fixation with DF-LCP through lateral approach and as per standard protocol. The follow-up results were analyzed clinically and radiologically, using the “ Schatzker and Lambert criteria” at once in a month for the first three months, once in three months upto one year and once in six months after that up to two years.
Harmonization of the human resource audit in the field of international practice
Authors: Bieliaieva N.S.
Published: July 2020

The article explores the possibilities and problems of the process of harmonization of the HR audit in the field of international practice, taking into account the specifics of the market environment of Ukraine. The views of different authors on the problem of HR auditing were investigated. The idea was justified that the harmonization of accounting and financial reporting of economic entities is closely linked with the globalization of economic processes and the economy as a whole on a global scale, the processes of informatisation and digitalization of society, the same as for HR processes. During considering the concept of “HR audit” it should not be forgetting about the legislative component — HR audit is aimed, inter alia, at identifying violations with the law for timely management of weaknesses in the policy of the enterprise in the field of labor. Categorization of observations by impact of importance (high-risk, medium-risk, low-risk — categorization) was investigated; examples for high-risk observations (on the example of: workforce planning, service contract modalities) and medium-risk (on the example of: recruitment process governance, alignment of strategy and work plans, HR functional capacity in Country Offices, talent acquisition in Cos, recruitment processes in Cos, employee on-boarding, training and separation, national non-staff salary scales and pay adjustments, staffing and structure review exercises, social security transfers to service contracts, automation, information and data management, oversight of HR functions in Cos) are given in consideration with agreed actions of HRM and auditor. The ratings (satisfactory, partially satisfactory or unsatisfactory) of an HR audit that are part of the system of evaluating the adequacy of company’s audit risk management, control and governance processes were investigated. The point that the human resource auditing is something that many companies do annually, just as they audit their financial information (despite of their field of activity) is overlined in the article. The harmonization of the HR audit in the field of international practice is a process of unification of methods and principles of auditing in the form of standards is observed.
IMPLEMENTATION OF BEHAVIORISM LEARNING THEORIES IN ARABIC LEARNING PLANNING
Authors: Syafe'i Isop , Ulfah Ai Fitria
Published: July 2020

The purpose of this research to know the theory of learning behaviorism through BF Skinner's thinking in planning Arabic learning. This research method is literature study with qualitative approach, data is extracted through literature study and analyzed through content analysis. The primary data source in this study is The Theories of Learning by Ratna Willis Dahar. While secondary data in this study were obtained from literature exploration related to the discussion. The results of the analysis show that the BF Skinner theory can be applied in Arabic learning planning that is the material being studied is analyzed up to the units organically, the subject matter is used a module system, learning evaluation must be notified to students, if incorrectly corrected and if properly strengthened, more tests emphasized for the sake of diagnostics, in education prioritizing changing the environment to avoid violations so as not to punish, prioritizing the needs that will lead to operant behavior, the behavior desired by educators are rewarded, the desired behavior is analyzed in small ways, increasingly reaching goals, implementing mastery learning is to learn the material thoroughly according to each time because each child has a different rhythm.
Startup Idea Validation using Machine Learning
Authors:   Computer Science and Engineering, MIT Academy of Engineering, Pune, India., Kumar Sudhanshu , Guirish Bhargav ,   Computer Science and Engineering, MIT Academy of Engineering, Pune, India., Umale Akshay ,   Computer Science and Engineering, MIT Academy of Engineering, Pune, India., Ganjewar Pramod ,   Computer Science and Engineering, MIT Academy of Engineering, Pune, India.
Published: July 2020

According to experts, 90 out of 100 Startups fail within the first year of their launch. There are several reasons behind that but one of the very first and major reasons is Idea Validation. The Entrepreneurs are so excited about their idea that they forget about this very important step, which fails the Startup. Startup Idea Validation tool provides the entrepreneurs with a roadmap by asking the right questions relevant to their ideas and providing suggestions and improvements based on the inputs provided by the User. We are using Linear Regression and Support Vector Machine to train the machine on the Expert Dataset provided and we conclude the result based on that. With this, we’ll be able to train the machine with an accuracy of up to 99.99%. There are no other tools available so far which can validate a Startup idea automatically. This tool can be a great breakthrough in the field of Startups.
PENDIDIKAN BAHASA INDONESIA DI JEPANG
Authors: Funada Kyoko
Published: July 2020

BIPA is an abbreviation for Indonesian for Foreign Speakers. Precisely, Indonesian language skills learning programs, namely speaking, writing, reading, and listening to foreign speakers. In Japan, Indonesian is taught at universities, language schools and several high schools. In some universities Indonesian language can be learned as a second foreign language / language of choice after they learn English. In general, the material taught is only about language. However, there are several universities that have Indonesian Language Study Programs or Programs. The scope of teaching is broader. In addition to language, those who take the program can study the arts, culture, literature, religion, social, economics, and politics of Indonesia. Can I study Indonesian language in a department or study program that can be called BIPA? According to the author it is different from BIPA because BIPA is only limited to language learning. Indonesian (Malay) education in Japan began in the early 1900s in Tokyo. This article discusses the development of Indonesian language education in Japan from the past to the present.