bluuebunny/crossref_metadata_2025 huggingface dataset:
Does hinge sidedness influence laterality of C5 palsy after expansile open-door cervical laminoplasty?
Authors: Levi David J. , Brusko G. Damian , Levi Allan D. , Wang Michael Y.
Published: September 2023

OBJECTIVE

Cervical expansile open-door laminoplasties (EOLPs) have an open side and a hinge side, with the open side being bridged by grafts or miniplates. The authors explored the possibility that the open-door side might have a greater incidence of C5 palsy due to a greater stretch of the ipsilateral C5 nerve root.

METHODS

This study was a retrospective review of prospectively collected data over a period of 25 years specifically assessing surgical complications. Included were patients who underwent EOLP for myelopathy, radiculopathy, or mild central cord injuries (American Spinal Injury Association Impairment Scale [AIS] grade D). Exclusion criteria included preexisting C5 weakness; patients with AIS grade A, B, or C injury; and added instrumentation or additional surgical procedures. Patients were monitored postoperatively for C5 palsy or any other complications. A comparison group included patients who underwent cervical laminectomy and fusion (CLF).

RESULTS

A total of 327 laminoplasties were collected, and 31 patients were excluded because of severe spinal cord injury (AIS grades A–C), 3 for preoperative C5 weakness, and 21 for instrumentation or additional surgical procedures. Thus, 272 patients were analyzed with a mean age of 59.9 years (range 22–88 years). Diagnoses at presentation were cervical myelopathy (84.1%), central cord syndrome (7.2%), cervical myeloradiculopathy (3.4%), ossification of the posterior longitudinal ligament (1.9%), and other (3.4%). The most common complications were C5 palsy (n = 7, 2.6%) and wound infection (n = 7, 2.6%). Of the 7 cases of postoperative C5 palsies in this study, 6 occurred on the side of the open door. Of the C5 palsies, 2 were mild, 3 were moderate, and 2 were severe. Two of the 7 C5 palsies had a delayed (> 24 hours) onset. The C5 palsy incidence after CLF was 2.7% with no side preference.

CONCLUSIONS

C5 palsy after cervical decompression for myelopathy is a known occurrence, with a rate of 2.6% in the current study. The authors found that C5 palsies more commonly occur on the open side of the laminoplasty. This could be due to a greater manipulation of the nerve root on the side of the open door or greater stretch of the C5 root on the open-door side. If clinical symptoms and anatomical stenosis are symmetric, the authors recommend creating the laminoplasty hinge on the patient’s dominant side to minimize potential loss of dominant proximal arm function.
Treatment of Knee Synovitis from Psoriatic Arthritis with Platelet Rich Plasma Injection
Authors: Mazzei Nicolle , Hall Arielle , Clinton Cody
Published: September 2023

Psoriatic arthritis has been known to cause many inflammatory clinical features, including synovitis. In the past, synovitis has been primarily treated with NSAIDs, corticosteroid injections, and synovectomy when needed. This report outlines a 49-year-old female with synovitis caused by psoriatic arthritis who did not respond to conventional treatment options and was apprehensive to surgery. She was offered a platelet rich plasma (PRP) injection as alternative therapy to a synovectomy. This case explores the use of PRP injections as a potential treatment modality for patients with synovitis caused by psoriatic arthritis. This patient was able to show improvement in her symptoms after the use of the platelet rich plasma injection.
A method to detect thermal damage in bovine liver utilising diffuse reflectance spectroscopy
Authors: Surazynski Lukasz , Nieminen Heikki J. , Mäkinen Markus J. , Nieminen Miika T. , Myllylä Teemu
Published: September 2023

When light is illuminated using a broad spectrum and detected without physical contact between source and detector the method is often referred as diffuse reflectance spectroscopy (DRS). Combined with newest computational algorithms, DRS may reach high performance in near future in tissue characterization and pathology. In this study, we show that DRS can be used to automatically differentiate untreated fresh liver tissue from heat-induced and chemically induced tissue denaturation in bovine liver ex vivo. For this, we used a thresholding algorithm that was developed and tested using 10-fold cross validation. Our results indicate that DRS has potential to detect pathological tissue processes that result in tissue injury and ultimately tissue necrosis. The detection of necrosis is important for many medical applications, not least for tissue sampling by biopsy needle, where additional guidance to commonly used ultrasound would be welcome. Furthermore, cancer tissue is prone to necrosis as a result of tissue hypoxia and due to cancer treatments.
Potential Impacts of Climate Change on Reservoir Water Quality in An Giang Province, Vietnam
Authors: Phung Luu Kim , Han Tran Gia , An Tran Thi Thuy , Lavane Kim , Kumar Pankaj , Downes Nigel K. , Minh Huynh Vuong Thu
Published: September 2023

As water scarcity puts over 80% of the world’s population at risk, water quality has become a major environmental topic. In particular, climate change has jeopardised the quality of water within the Vietnamese Mekong Delta (VMD), a key agronomic and aquaculture hub. A modest canal system and small to medium-sized reservoirs in the semi-mountain region of An Giang province contribute to a less abundant water supply and a tendency for water quality reservoirs to deteriorate. The water quality index method and descriptive technique were used in this study. The results show that in the period 2017–2020, some water quality indicators exceeded the permissible limits of the Vietnamese standards for domestic surface water in column B1 (NO3-, Total Coliform, BOD5, COD, N-NH4+) but are consistent, but are allowed for use in irrigation purposes. Findings show that for many years, WQI values in Tinh Bien and Tri Ton districts have diminished because of wastewater pollution. WQI values near the shores of O Tuk Sa Reservoir (Tinh Bien), Lo^˜i đánh máy (Tri Ton), and O Ta Soc Reservoir (Tri Ton) diminished over time. According to the WQI index, the water quality at the reservoir monitoring stations has fluctuated throughout the years, so it is advised that people implement water purification techniques for long-term well-being.
Investigating Variations and Trend Analysis for Temperature and Precipitation as a Result of Climate Change in Rajasthan, India
Authors: Porwal Vratika , Choudhary Mahendra Pratap
Published: September 2023

Climate change is a pressing issue that is affecting the lives and livelihoods of millions of people across the world. This study investigates the trend analysis and spatial-temporal variations of temperature and precipitation on a monthly, seasonal, and annual basis in Rajasthan state, India, over the past 40 years (1981-2020). The trend analysis of temperature and precipitation were analysed using the Mann-Kendall test at the confidence level of 95%. The magnitude (slope) was determined by using Theil-Sen’s slope test. The results of the analysis revealed significant positive and negative trends of temperature and precipitation observed on a monthly, seasonal, and annual basis in all the 33 districts of Rajasthan state. The summer season experienced the maximum average temperature, while the winter season had the minimum. The study also found that the northern and western parts of Rajasthan experience “Mawat” rain during the winter due to cyclones happening in the Mediterranean Sea during that season. The annual average temperature and precipitation were observed to be maximum in the southern part and minimum in the northern and western parts of the state. The findings of this study provide valuable information for the future management of water resources and the likely impact of activities on the hydrologic cycle and natural resources in Rajasthan state.
Huntingtin Plays a Role in the Physiological Response to Ethanol in Drosophila
Authors: Clabough Erin B.D. , Aspili Christia , Fussy William S. , Ingersoll James D. , Kislyakov Amy , Li Elizabeth S. , Su Meng-Jiuan , Wiles Dustin B. , Watson Thomas E. , Willy Aaron J. , Thomas Vinyard H. , Mollica III Philip J. , Taylor James V. , Smith Cody W. , Roark Dallas A. , Tabrani Zachary P. , Thomas Harris L. , Shin Mimi , Venton B. Jill , Hayes David , Sipe Conor W.
Published: September 2023

Background: Huntingtin (htt) protein is an essential regulator of nervous system function through its various neuroprotective and pro-survival functions, and loss of wild-type htt function is implicated in the etiology of Huntington’s disease. While its pathological role is typically understood as a toxic gain-of-function, some neuronal phenotypes also result from htt loss. Therefore, it is important to understand possible roles for htt in other physiological circumstances. Objective: To elucidate the role of htt in the context of ethanol exposure, we investigated how loss of htt impacts behavioral and physiological responses to ethanol in Drosophila. Methods: We tested flies lacking htt for ethanol sensitivity and tolerance, preference for ethanol using capillary feeder assays, and recovery of mobility after intoxication. Levels of dopamine neurotransmitter and numbers of dopaminergic cells in brains lacking dhtt were also measured. Results: We found that dhtt-null flies are both less sensitive and more tolerant to ethanol exposure in adulthood. Moreover, flies lacking dhtt are more averse to alcohol than controls, and they recover mobility faster following acute ethanol intoxication. We showed that dhtt mediates these effects at least in part through the dopaminergic system, as dhtt is required to maintain normal levels of dopamine in the brain and normal numbers of dopaminergic cells in the adult protocerebrum. Conclusions: Our results demonstrate that htt regulates the physiological response to ethanol and indicate a novel neuroprotective role for htt in the dopaminergic system, raising the possibility that it may be involved more generally in the response to toxic stimuli.
Demand side management using a novel archimedes optimization algorithm in a smart grid environment
Authors: Lakshmi H. , Queen M.P. Flower
Published: September 2023

Demand side management (DSM) is a smart grid technology that enables consumers to make decisions about their energy use, lowers energy suppliers’ peak hour demand, and changes the load profile. Demand Side Management (DSM) is regarded as the most significant method used in a Smart Grid (SG), as it helps consumers produce accurate information about their electrical energy usage and assists the utility in reducing peak load demand and reshaping the demand curve. By effectively utilising storage with Renewable Energy Systems (RES), DSM seeks to reduce peak demand, electricity costs, and emission rates. In this paper, we have proposed a load-shifting method for the DSM with a large number of controllable devices. The load-shifting issue has been handled hourly, throughout the course of a 24-hour day, in order to reduce the peak demand, lower the power cost, and minimise the Peak to Average load Ratio (PAR). The Archimedes Optimization (AO) method has been utilised in residential loads in SG to achieve the goal of load shifting by minimising of the problem to the DSM. The simulation findings demonstrate that the suggested demand side management technique generates significant cost savings while lowering the smart grid’s peak load demand.
Time and frequency domain pre-processing for epileptic seizure classification of epileptic EEG signals
Authors: Dutta Kusumika Krori , Manohar Premila , Indira K.
Published: September 2023

Although epilepsy is one of the most prevalent and ancient neurological disorder, but, still difficult to identify the specific type of seizure, due to artefacts, noise, and other disturbances, because of acquisition of Scalp EEG. It necessitating the use of skilled medical professionals as incorrect diagnosis lead to wrong Anti Seizure Drug (ASDs) and face it’s side effects. On the other hand machine learning plays a crucial role in seizure detection by analyzing and identifying patterns in brain activity data that are indicative of seizures. It can be used to develop predictive models that can detect the onset of seizures in real-time, allowing for early intervention and improved patient outcomes. Most of the research work focuses on seizure detection using various machine learning techniques pre-processed by different mathematical models. But, very less attention is paid towards seizure type detection. In this study, multiple Machine and Deep Learning algorithms were used in conjunction with time-domain and frequency-domain pre-processing to classify epileptic seizures into multiple types. The ictal period of various seizure types were extracted from Temple University Hospital EEG (TUHEEG) and the pre-processed data was tried out with multiple classifiers, including support vector classifiers (SVC), K- Nearest Neighbor (KNN), and Long short term memory (LSTM), among others. By using SVM, KNN, and LSTM, multiclass classification of seven types of epileptic seizures with 19 channels were considered for each EEG data and a 75–25 train–test ratio was accomplished with 90.41%, 94.46%, and 86.2% accuracy respectively. Epileptic seizure’s ictal phase EEG signals are categorized using a variety of machine learning(ML) and deep learning(DL) methods after being pre-processed using time domain and frequency domain approaches. The KNN yields the best results of all.
Threat assessment based on single-valued neutrosophic TOPSIS and three-way decision
Authors: Xu Dongsheng , Sun Yuhuan , He Xinyang
Published: September 2023

This paper provides a novel target threat assessment model that utilizes TOPSIS and three-way decision-making under a single-valued neutrosophic environment. The presented model provides theoretical support for combat decision-making in complex battlefield environments with uncertain information. The model employs single-valued neutrosophic sets to handle uncertain data, which enhances the descriptive ability of information. The maximum deviation method is used to calculate attribute weight factors, which highlights the importance of each attribute. The final target threat ranking is obtained based on the relative closeness coefficient of each target. Furthermore, the proposed model constructs a multi-attribute aggregation loss function matrix for each target, sets the risk avoidance coefficient under the knowledge of the battlefield condition, and calculates the decision threshold of each target using three-way decision theory. This method produces the classification of the target choice. The numerical examples and comparison analysis demonstrate that the suggested model can handle ambiguous scenario information effectively and reasonably, transform traditional decision-making ranking results into three-way classification findings, and provide a rationale for choosing an attacking target.
An integrated approach to design and evaluate Chinese-style stools
Authors: Min Qu , Zhaoxian Ren , Jiang Wu
Published: September 2023

To inherit and promote the excellent design characteristics of Chinese-style furniture, this study focuses on Chinese-style stools and proposes an integrated design and evaluation approach with combination of shape grammar, KANO model, and entropy-weighted VIekriterijumsko KOmpromisno Rangiranje (VIKOR) methods. Firstly, based on the initial forms of five Chinese-style stools, a shape feature library is constructed by extracting shape features using regional cultural symbols. Secondly, combining shape grammar and inference rules, innovative design alternatives are generated for Chinese-style stools, incorporating regional cultural symbol features. Thirdly, an in-depth investigation of Chinese-style furniture market is conducted, and user requirements are analyzed using KANO model questionnaire, categorizing the requirements into three attributes: appearance, technological, and economic. Based on KANO model’s classification of user requirements, a set of 14 evaluation criteria for Chinese-style stools is established. Finally, to avoid subjective factors in weighting the criteria, the entropy-weighted method is applied, and VIKOR method is utilized to obtain the optimal ranking of the design alternatives for Chinese-style stools, ultimately selecting the optimal alternative. The results show that based on VIKOR method, the optimal solution is the same with comparison to the results obtained from Technique for Order Preference by Similarity to Ideal Solution (TOPSIS), preference ranking organization methods for enrichment evaluations (PROMETHEE) and elimination and et choice translating reality (ELECTRE) methods. In addition, to verify its ergonomic characteristics, feasibility and rationality, the optimal alternative is simulated by JACK software. By integrating shape grammar, KANO model, and the entropy-weighted VIKOR method, this study provides some insights for incorporating regional cultural symbols into the design of Chinese-style furniture and exhibits certain advantages in terms of comprehensive evaluation, user orientation, decision objectivity, and consideration of diversity.
PLM-PGHC: A novel de-biasing framework for robust question answering
Authors: Yu Shujuan , Wu Mengjie , Zhang Yun , Xie Na , Huang Liya
Published: September 2023

Reading Comprehension models have achieved superhuman performance on mainstream public datasets. However, many studies have shown that the models are likely to take advantage of biases in the datasets, which makes it difficult to efficiently reasoning when generalizing to out-of-distribution datasets with non-directional bias, resulting in serious accuracy loss. Therefore, this paper proposes a pre-trained language model based de-biasing framework with positional generalization and hierarchical combination. In this work, generalized positional embedding is proposed to replace the original word embedding to initially weaken the over-dependence of the model on answer distribution information. Secondly, in order to make up for the influence of regularization randomness on training stability, KL divergence term is introduced into the loss function to constrain the distribution difference between the two sub models. Finally, a hierarchical combination method is used to obtain classification outputs that fuse text features from different encoding layers, so as to comprehensively consider the semantic features at the multidimensional level. Experimental results show that PLM-PGHC helps learn a more robust QA model and effectively restores the F1 value on the biased distribution from 37.51% to 81.78%.
A generalized integrated group decision-making framework for computer network security evaluation with Interval Neutrosophic information
Authors: Chen Hao , Su Ze , Xu Xiangqian
Published: September 2023

The rapid development of global information technology, especially the emergence and widespread application of the Internet, has enabled information technology to quickly penetrate into various fields of the economy and society. Informatization and networking have become important features of today’s era. However, while people enjoy the tremendous progress brought by information technology to humanity, the openness and security vulnerabilities of computer networks have also made network information security issues increasingly prominent. The invasion of hackers, the continuous generation and spread of computer virus, and the rampant use of rogue software have all caused great economic losses to individuals, enterprises, and countries. The computer network security evaluation is a multiple-attribute group decision making (MAGDM). Then, the TODIM and TOPSIS method has been established to deal with MAGDM issues. The interval neutrosophic sets (INSs) are established as an effective tool for representing uncertain information during the computer network security evaluation. In this manuscript, the interval neutrosophic number TODIM-TOPSIS (INN-TODIM-TOPSIS) method is established to solve the MAGDM under INSs. Finally, a numerical example study for computer network security evaluation is established to validate the INN-TODIM-TOPSIS method. The main research contribution of this paper is established: (1) the INN-TODIM-TOPSIS method is put up for MAGDM with INSs; (2) the INN-TODIM-TOPSIS method is put up for computer network security evaluation and were compared with existing methods; (3) Through the detailed comparison, it is evident that INN-TODIM-TOPSIS method for computer network security evaluation proposed in this paper are effective.
Rapid eye movement sleep behaviour disorder in brain injury: A complex case requiring close coordination of care
Authors: Krasna Daniel , Colebank Brittaney , King Sophia , Bechtold Kathleen T.
Published: September 2023

BACKGROUND: Neurorehabilitation is interdisciplinary and cross-sectorial, requiring the coordinated effort of diverse sectors, professions, patients and communities to manage complex condition-related disabilities. A more holistic approach to experimental rehabilitation can incorporate individualized treatment plans into rehabilitation research to improve overall clinical care. OBJECTIVE: This case aims to highlight the benefit of collaboration between neurology, psychiatry, physiatry and rehabilitation therapists to successfully rehabilitate complex patients. CASE PRESENTATION: A 72-year-old gentleman with history of depression, anxiety and sleep difficulties presented to our institution one year after a stroke for help managing exacerbations of his premorbid conditions. The patient had a hemorrhagic stroke which required craniectomy and led to seizures. Past history was unclear regarding what workups had been done but was suggestive of rapid eye movement (REM) sleep behavior disorder (RBD). RESULTS: Given the numerous medications patient had tried in the past and since his stroke, a true multidisciplinary team was needed and his case required close coordination to successfully diagnose the reason for each of his symptoms and to provide treatments and rehabilitation. CONCLUSION: The correct diagnosis was only achieved by clear communication among team members which allowed for optimal treatment and improvement with therapies.
ENGINEERING OF WATER PROTECTION ZONES AS A PRIMARY MEASURE TO CONSERVE WATER BODIES
Authors: Mykhailyk Olha
Published: September 2023

The shortage of clean water is one of the biggest threats facing our society today. In order to improve the deteriorating modern state of the river ecological systems of Ukraine, it is necessary to start with the professional organization of water protection zones and coastal protection strips. The protection and preservation of coastal areas directly affects the improvement of the state of the water area, because the reservoir with its coastal zone constitutes an interconnected river ecological system. All protection, revitalization, and engineering measures to improve the condition of the reservoir and the coastal area have the expected result in the case of covering the entire river basin.

Engineering measures for arranging water protection zones are considered. The importance of the professional organization of water protection zones of coastal areas for the protection and revitalization of river ecological systems is indicated. Emphasis is placed on phytoremediation measures as the optimal solution for the restoration of natural complexes.

Having professionally selected the composition and size of plant communities, it is possible to reduce the impact of adjacent territories on the river, retain a significant share of wastewater, slowing down its speed by almost 10 times, prevent soil erosion, siltation of the stream, increase the water content of the river, etc. Taking into account the specific needs of each river, available plots of land and features of the territory, phytomelioration works are carried out in a wide range: from shore fortification with individual trees or shrubs, the creation of forest strips, to planting and planting trees on large areas. Phytomeliorative works should be aimed at restoring the optimal ratio of natural and anthropogenically altered landscapes.

To preserve water resources, it is necessary, first of all, to strengthen the regime of water protection zones. In the coastal areas, forest plantations and meadows, wetlands and arable land should be optimally combined. Streamlining of rivers with the use of modern methods of management, protection and restoration of their water resources allows creating favorable conditions for the formation of an ecologically safe state of the river and its basin.
MASS RESIDENTIAL CONSTRUCTION AS AN ELEMENT OF CRISIS ARCHITECTURE
Authors: Holyk Jolana , Bagrij Nataliia , Vantyukh Diana
Published: September 2023

The world's population loses their homes due to natural disasters and wars every year, many international organizations have been created to eliminate such consequences. Architects as volunteers also make efforts to design typical low-cost mass housing., there is a concept of crisis architecture to denote this phenomenon. Its feature is the fastest possible reconstruction of housing for people in disaster zones. The next term discussed in the article is urbicide, the purposeful destruction of cities caused by wars, terrorist attacks, and other aggressive actions that we have in Ukraine today.

The purpose of the article is to reveal the features of mass housing architecture in its relationship with crisis phenomena and urbicide in society. For this purpose, the possibility of reconstruction, reconstruction and development of the architectural and urban structure of cities in the post-crisis period is considered. The features of the crisis architecture of countries and cities affected by wars, as well as floods, fires and other natural disasters (Rotterdam, Hiroshima, Bismaya, Skopje) are analysed. Foremost, the restoration of the engineering infrastructure was observed. Work on solving the housing problem consisted in the repair of damaged buildings, the reconstruction of large apartments into small apartments and the construction of typical temporary low-rise buildings 3 available raw materials. Unified 4-5- story series of economy houses were popular in post-war France, Hungary, Slovakia and other countries. Disadvantages of such housing include chaotic construction, simplification of architectural solutions, lack of individual stylistic features. Later, the temporary residential quarters were dismantled. At the same time, a significant part of such panel houses remains inhabited even in our time. 

Ukraine was significantly affected by the Second World War. Mass construction according to typical projects took place in the 60s, as a result of which about 23% of the country's housing stock has physical and moral deterioration. In view of the military actions, it is extremely important to use the international experience of rebuilding cities, to carefully approach the selection of projects, focusing on the economic component, the safety of residents and high-quality architectural solutions.
URETHRAL INJURY IN REGIONAL HOSPITAL IN THE BPJS ERA: A CASE REPORT
Authors: Muhammad Omar R  , Muhammad Taufiq Reza
Published: September 2023

ABSTRACT

Objective: To present a case of urethral injury treated in a male adult. Case(s) Presentation: A 48 year old Asian male patient previously involved in a motor vehicle accident presented to the hospital with a chief complaint of pain and bleeding from the genitalia. On examination, it is revealed bleeding from the urethral meatus, pain in touch, palpable bladder, high riding prostate, and a butterfly-shaped bruising on the perineum. X-ray examination demonstrated soft tissue mass in the right scrotal region. The patient is diagnosed with urethral rupture with urinary retention and then underwent ultrasonography-guided cystostomy and perineal hematoma evacuation. The patient is followed-up 1 month later with a complaint of difficulty in voiding and erectile dysfunction. The patient is then diagnosed with urethral stricture and underwent direct vision urethrotomy. Discussion: Urethral injury is a rare type of injury of genitourinary trauma that may cause long term morbidity such as strictures, incontinence, impotence, and infertility. Urethral injury can be classified into posterior urethral injury which is associated with pelvic fracture and anterior urethral injury which is associated with blunt trauma. The gold standard of radiographic examination in urethral injury is dynamic retrograde urethrography. Prompt diagnosis, staging, and selecting intervention must be done for minimalizing complications. Sequelae may also develop which also affects quality of life. The usage of universal health coverage such as BPJS in In Indonesia can increase the accessibility of medical treatment. Conclusion: Urethral injury is a rare injury that requires prompt and careful management to minimize complications and increase the patient’s quality of life.

Keywords: Urethral Injury, urethrotomy, urethral stricture.
RISK FACTORS ASSOCIATED WITH FEMALE SEXUAL DYSFUNCTION IN MARRIED WOMEN WORKING IN HEALTH CARE SYSTEM
Authors: Ridwan Fanny Riana , Ali Zulfikar , Gautami Hidayah Kemala , Faradila Utari Nazlah , Innayah Ulfa
Published: September 2023

ABSTRACT

Objective: In this study, we want to evaluate the risk factors associated with sexual dysfunction in married women working in health care system. Material & Methods: The sexual function was assessed in the questionnaire using Female Sexual Function Index (FSFI). The analysis was conducted using chi-square test or Fisher Exact Test. Results: All participants who were overweight/obese had highest pain problem (p-value 0.034). Women with diabetes mellitus had higher satisfaction problems (p=0.002, OR 13.13, CI 1.73-99.91). The females who used contraception had significantly lower orgasm problems (p<0.004, OR 0.33, CI 0.15-0.72. Participants who worked as medical staff such as nurse/midwife, pharmacist, radiographer had higher pain problems (71.43%) compared to medical staff (administration staff) (OR 27.47, CI 3.73-202). Conclusion: The BMI (overweight/obesity), diabetes mellitus, the use of contraception, and the medical occupation were the significant risk factors to sexual dysfunction problem in women working in the hospital.

Keywords: Female sexual dysfunction, working women, hospital.
URINARY DIVERSION AFTER RADICAL CYSTECTOMY, ORTHOTOPIC NEOBLADDER VS ILEAL CONDUIT: A SYSTEMATIC REVIEW AND META-ANALYSIS OF POSTOPERATIVE COMPLICATION
Authors: Fahri Muhammad , Gampo Alam Irdam
Published: September 2023

ABSTRACT

Objective: The purpose of this study is to compare orthotopic neobladder (ONB) and ileal conduit (IC) formation in terms of surgical outcome and complication. Material & Methods: Computerized bibliographic search on different databases related to this study. The PICO criteria method was applied to define research eligibility, per PRISMA recommendations and conducted a systematic review of the literature with meta-analysis. Weighted mean differences with 95 percent confidence intervals were used to compare continuous outcomes. Results: There were 479 publications were discovered and only 6 studies fulfilled the criteria included. The random-effect model's pooled result for urinary leakage complication revealed a significant difference of 1.62 between ONB and IC with higher incidence in neobladder group (95 percent CI, 1.85, 8.69, P = 0.0004) with non-significant heterogeneity (Chi2 = 0.65, df = 3 (P = 0.89), I2 = 0%). Other complications (ileus complication, anastomosis site stenosis, sepsis, urinary infection) showed non-significant difference. Conclusion: Because of the heterogeneity in several aspects of the analyzed papers, further study comparing Orthotopic Neobladder and Ileal conduit in terms of complication following urinary diversion are needed to conﬁrm superiority of ONB or IC as the urinary diversion of choice.

Keywords: Orthotopic neobladder, ileal conduit, urinary diversion, radical cystectomy
LONG URETERIC STRICTURES MANAGED BY USING BUCCAL MUCOSAL GRAFTS
Authors: Nerli Rajendra , Patel Keyur , Rai Shreyas , Jogula Abhinay , Jasuja Pranav , Setya Nishant
Published: September 2023

ABSTRACT

Objective: This study aims to describe the reconstruction of long ureteric strictures using buccal mucosal patch grafts and to report the short term outcome. Material & Methods: We retrospectively looked at our hospital inpatient and outpatient records of all patients who underwent surgical treatment for benign ureteric strictures. Imaging records and films, histopathological reports were reanalysed. The short term outcomes were also noted. Results: During this 10 years’ study period 8 patients (six Males and two Females) underwent 10 buccal mucosal grafts procedures. The mean age of the patients was 36.25 years and the mean length of the stricture was 7.13.41 cm.  There were intraoperative complications noted and none of the patients needed either intra or post-operative blood transfusions. Serum creatinine remained stable at 6 and 12 weeks after surgery. Radioisotope renograms done 12-16 weeks after surgery showed improvement in function on the affected sides in all patients with adequate drainage. Conclusions: Buccal mucosal patch grafting and omental wrapping is feasible, effective, less complicated and associated with good outcomes at short term follow-up.

Keywords: Reconstruction, ureteric stricture, buccal mucosa.
HIGH FLOW PRIAPISM IN 7 YEARS-OLD BOY AFTER ACCIDENTALLY CONSUMING APHRODISIAC CHOCOLATE: A CASE REPORT
Authors: Samudra Fathan Satria , Seputra Kurnia Penta , Daryanto Besut , Nurhadi Pradana
Published: September 2023

ABSTRACT

Objective: This case report aimed to present our experience of conservative treatments for High Flow Priapism in children. Case(s) Report: A 7 years old boy presented with persistent and painless erections without sexual stimulation for 24 hours, the erection was first noticed when he woke up in the morning after accidentally consuming aphrodisiac chocolate 2 days before admitted to the hospital. There was no previous history of priapism and trauma or other risk factors. Discussion: Laboratory studies were within normal limits. Physical examination revealed a fully erect, nontender penile with rigid corpora cavernosa, soft glans, and erection hardness scale (EHS) 3. A cavernosal blood gas analysis was collected with the following values PH 7.41, pO2 117,7 mmHg, and pCO2 24, 8 mmHg. With diagnosis of High Flow Priapism, he was observed and got conservative treatments; ice and site-specific compression and after that EHS become 1. On follow-up after 2 months reported that patient had normal erections with no further episodes of priapism. Conclusion: High flow priapism in old boy after accidentally consuming aphrodisiac chocolate can managed by conservative therapy with favourable outcome.

Keywords: Aphrodisiac chocolate, penile erection, priapism.
Boletín Económico Regional : Noroccidente, II trimestre de 2023
Authors:   Sección Sucursales Regionales Estudios Económicos
Published: September 2023

Durante el segundo trimestre de 2023 se agudizó la desaceleración económica de la región Noroccidente, afectada por la inflación, mayores tasas de interés y un ambiente de incertidumbre, que repercutieron en la reducción de la demanda. Varias actividades productivas tuvieron desmejora en su comparativo anual, en especial la industria, las ventas minoristas y la mayoría de los indicadores de la construcción y el sector agropecuario, este último, con la excepción del mayor abastecimiento agrícola. Asimismo, bajó la ocupación hotelera y gran parte de los componentes del transporte. En contraposición, las exportaciones crecieron, impulsadas por las de oro y vehículos. Por su parte, la recepción de remesas y las importaciones fueron menores. En cuanto al mercado laboral, en Medellín y el área metropolitana bajó la tasa desempleo, mientras en Quibdó aumentó y continuó como la más elevada del país. Finalmente, se evidenció un menor ritmo de aumento en los precios al consumidor pese a permanecer en niveles altos.
Boletín Económico Regional : Suroriente, II trimestre de 2023
Authors:   Sección Sucursales Regionales Estudios Económicos
Published: September 2023

Durante el segundo trimestre de 2023, la economía de la región Suroriente registró balances disímiles entre sus actividades económicas frente a lo observado un año atrás. De esta forma, se señaló avances especialmente en variables del sector agropecuario como producción de arroz, fruto procesado de palma y sacrificio de ganado bovino, aunado al crecimiento en las percepciones de ventas, con excepción de la comercialización de vehículos y motos que cayó. Se presentaron descensos en indicadores relacionados con el ramo de la construcción como área aprobada, despachos de cemento y venta de vivienda nueva, a lo que se sumó la baja en transporte aéreo. En cuanto al comercio exterior, disminuyeron las exportaciones, especialmente por el menor dinamismo del Meta, mientras las importaciones evidenciaron un alza. Por último, en Villavicencio se redujo la tasa de desempleo y la inflación se mantuvo alta, aunque se ubicó por debajo del resultado nacional.
Study of Dynamic Loads of the Front Loader Frame Using 3D Computer Models in the Siemens NX Environment
Authors:   Kharkiv National Automobile Highway University, Kharkiv, Ukraine, Sherbak Oleh , Suminov Andrey ,   Kharkiv National Automobile Highway University, Kharkiv, Ukraine, Khachaturyan Serhiy ,   Central Ukrainian National Technical University
Published: September 2023

When designing new construction and road machines, a variety of CAD and CAE computer programs are used. The designer has the ability to set certain strength properties of the future structure using finite element calculations, and after the first prototype is made, the moment comes when it needs to be tested for loads applied during technological operations to confirm the preliminary strength calculations. The goal of this work is to compare the test results of 3D models of two load-bearing systems of the T-156B loader, one of which is the original and the other a fivefold reduced copy. The result of the comparison is a reduction factor, the calculation of which will allow us to determine how and how many times the load is reduced when scaling 3D models. Previous work on this topic was done in the Ansys calculation complex, but the long process of calculating the task, importing, and complex process of configuring the model forced us to switch to a faster Siemens NX software complex. This software package has a clear and simple interface while performing calculation tasks much faster than Ansys. In this work, similarity coefficients were calculated for two more common cases of forklift operations: moving a full bucket over an uneven surface and colliding with an obstacle while filling the bucket. Thus, knowing these coefficients, it can be assumed that when modeling a new load-bearing system, by making a reduced copy of it in the appropriate scale and testing it for loading by means of computer modeling, or by conducting field tests, it is possible to calculate what loads will affect the model with natural dimensions. The article proposes a new solution for analyzing the strength of load-bearing systems at the design stage using the theory of similarity. This method makes it possible not to create a full-size model of a new load-bearing system (frame) in metal for testing. In accordance with the proposed method, it is enough to make a scaled simplified model of the future load-bearing system (frame), conduct strength tests and, in accordance with the similarity coefficient, calculate what loads will affect the full-size load-bearing system. This method can significantly reduce the cost of materials, production, and manufacturing time for new products.
Research on Protection of Car Parts from High-temperature Oxidation
Authors:   Western Ukrainian National University, Dzyadykevich Yuriy , Petryshyn Yury ,   Western Ukrainian National University, Bashutskyi Mihayno ,   Western Ukrainian National University, Buryak Mykola ,   Western Ukrainian National University
Published: September 2023

The article is devoted to the problem of investigating promising directions for protecting machine parts from high-temperature oxidation through the formation of a multilayer composition. Analyzing the results of conducted research on increasing the heat resistance of machine structural elements, it can be concluded that a multilayer composition is a promising protection against high-temperature oxidation. The study of the process of forming a slurry-based composition coating on machine parts has shown that boride phases are more stable compared to silicide phases with respect to the metallic substrate. The formation of boride-silicide and silicoboride phases at the interface ensures high stability of the borosilicide coating, making it suitable for manufacturing machine parts that are exposed to high temperatures. Based on the generalization and analysis of the results of works devoted to the problem of increasing the heat resistance of the elements of machine structures, it was established that a promising protection against high-temperature oxidation is a multilayer composition. The study of the forming process on the parts of the slip-composite coating machines showed that the boride phases are more stable in relation to the metal base than the silicide phases. Due to the formation of boride and silicide, silicoboride phases at the border, high stability of the borosilicide coating is ensured. Such a coating should be used for the manufacture of high-temperature equipment parts.
Ergonomic Provision of Requirements for the Comfort of a Trip in a Large-capacity City Bus
Authors:   Kremenchuk Mykhailo Ostrogradskyi National University, Zahorianskyi Volodymyr
Published: September 2023

The purpose of the paper is to is to analyze the main factors that determine the parameters of bus comfort when transporting passengers by large-capacity buses. Ensuring the comfort of passenger transportation in a city bus is determined by compliance with ergonomic requirements, which, in turn, depends on the design features of the space intended for passengers. The paper examines these questions in relation to single-deck single and articulated public buses with a capacity of more than twenty-two passengers, standing or sitting, except for the driver. From the point of view of the Ukrainian legislation and regulatory framework, the concepts of the capacity of a passenger bus, its comfort, the main factors that determine the comfort of large-capacity buses are analyzed. The scope of use of buses of different classes and categories according to the types of connections and the length of the routes is determined taking into account the features of the design of the buses regarding the comfort and safety of the transportation of passengers and luggage and ensuring proper travel conditions. The ergonomic requirements for the comfort parameters of buses, the procedure for determining their comfort class and the scope of their use by types of connections and traffic modes are also considered. It was found that the factors that determine the comfort of large-capacity buses include the design and location of the seats, climate control (operating while the engine is running), heating (operating while the engine is running), windows (glass tinting, sun protection equipment (curtains or curtains), individual lighting, a microphone and loudspeaker, the presence of a luggage compartment, the presence of sanitary equipment (toilets with water or chemical cleaning, wash basins), the presence of such amenities as a refrigerator, cafe bar, TV in the cabin, as well as the type of suspension (classic (mechanical) or pneumatic/ pneumomechanical).
Analysis of the Possibility of Applying Blockchain Technology in the Field of Supply Chain Management
Authors:   Cherkassy State Technological University, Shlionchak Ihor , Soltus Anatoliy ,   Cherkassy State Technological University, Rud Maksym ,   Cherkassy State Technological University
Published: September 2023

Human life in today's world is increasingly becoming faster and more popular in the digital format. Such a trend is observed in almost any sphere of human activity. And supply chain management is no exception. It is in the field of supply chain management that a digital approach to solving various problems is an extremely urgent task facing scientists today. The article provides a detailed analysis of the domestic and foreign experience of using blockchain technology. Positive experience of such use is shown. Attention is focused on the advantages and disadvantages of this technology. Monitoring of revenues of well-known global companies using the specified technology was carried out. The possibility of effective use of blockchain technology in the field of supply chain management in the Ukrainian perspective is emphasized, especially taking into account the European vector of the country's development. One of the European countries, namely Estonia, can be cited as an example of the effective use of blockchain technologies. One of the reasons for this is state support for digital technologies. The Estonian project is the most successful of the world's digital projects. Summing up, it should be noted that the application of blockchain technology has great prospects for effective use in the digital sphere of any human activity, in particular, in the management of supply chains. In the work, the main advantages and disadvantages of the mentioned technology were highlighted in order to establish greater efficiency of its application in the field of supply chain management. Based on the above, it should be concluded that blockchain digital technology is a promising system in the Ukrainian vector of European integration.
Formulation and Evaluation of Mouth Dissolving Film of Imipramine HCL
Authors: Mishra Soumya , Bais Nidhi , Kumar Jain Sachin
Published: September 2023

The main objective of the present study outlines a systematic approach for Design and Evaluation of Fast Dissolving Oral Films of Imipramine HCl to enhance the therapeutic efficacy and provide rapid onset of action in patients suffering from depression Because of patient may have trouble in swallowing a tablet or capsules. Mouth dissolving film is the most advanced oral solid dosage form due to its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved. Fast dissolving Oral film of Imipramine Hydrochloride was formulated by using solvent casting method with different concentrations of HPMC-E3. Film forming property of various grades of HPMC was investigated based on preliminary characteristics of various batches of FDOFs.