bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-Omics Profiling Identifies Candidate Genes Controlling Seed Size in Peanut
Authors: Liu Yang , Yi Congyang , Liu Qian , Wang Chunhui , Wang Wenpeng , Han Fangpu , Hu Xiaojun
Published: November 2022

Seed size is the major yield component and a key target trait that is selected during peanut breeding. However, the mechanisms that regulate peanut seed size are unknown. Two peanut mutants with bigger seed size were isolated in this study by 60Co treatment of a common peanut landrace, Huayu 22, and were designated as the “big seed” mutant lines (hybs). The length and weight of the seed in hybs were about 118% and 170% of those in wild-type (WT), respectively. We adopted a multi-omics approach to identify the genomic locus underlying the hybs mutants. We performed whole genome sequencing (WGS) of WT and hybs mutants and identified thousands of large-effect variants (SNPs and indels) that occurred in about four hundred genes in hybs mutants. Seeds from both WT and hybs lines were sampled 20 days after flowering (DAF) and were used for RNA-Seq analysis; the results revealed about one thousand highly differentially expressed genes (DEGs) in hybs compared to WT. Using a method that combined large-effect variants with DEGs, we identified 45 potential candidate genes that shared gene product mutations and expression level changes in hybs compared to WT. Among the genes, two candidate genes encoding cytochrome P450 superfamily protein and NAC transcription factors may be associated with the increased seed size in hybs. The present findings provide new information on the identification and functional research into candidate genes responsible for the seed size phenotype in peanut.
Convergence between Development and Stress: Ectopic Xylem Formation in Arabidopsis Hypocotyl in Response to 24-Epibrassinolide and Cadmium
Authors: Piacentini Diego , Della Rovere Federica , D’Angeli Simone , Fattorini Laura , Falasca Giuseppina , Betti Camilla , Altamura Maria Maddalena
Published: November 2022

Ectopic xylary element (EXE) formation in planta is a poorly investigated process, and it is unknown if it occurs as a response to the soil pollutant Cadmium (Cd). The pericycle cells of Arabidopsis thaliana hypocotyl give rise to EXEs under specific hormonal inputs. Cadmium triggers pericycle responses, but its role in EXE formation is unknown. Brassinosteroids (BRs) affect numerous developmental events, including xylogenesis in vitro, and their exogenous application by 24-epibrassinolide (eBL) helps to alleviate Cd-stress by increasing lateral/adventitious rooting. Epibrassinolide’s effects on EXEs in planta are unknown, as well as its relationship with Cd in the control of the process. The research aims to establish an eBL role in pericycle EXE formation, a Cd role in the same process, and the possible interaction between the two. Results show that 1 nM eBL causes an identity reversal between the metaxylem and protoxylem within the stele, and its combination with Cd reduces the event. All eBL concentrations increase EXEs, also affecting xylary identity by changing from protoxylem to metaxylem in a concentration-dependent manner. Cadmium does not affect EXE identity but increases EXEs when combined with eBL. The results suggest that eBL produces EXEs to form a mechanical barrier against the pollutant.
Temperature Dependence of the Kinetic Parameters of the Titanium–Magnesium Catalyzed Propylene Polymerization
Authors: Bronskaya Veronika , Manuyko Galiya , Aminova Guzel , Kharitonova Olga , Balzamov Denis , Lubnina Alsu
Published: November 2022

This paper provides a study of the liquid-phase polypropylene polymerization on a heterogeneous titanium–magnesium Ziegler–Natta-type catalyst. A kinetic model was developed that included the activation of potential active centers, chain growth, transferring the chains to hydrogen and monomer, and the deactivation of active centers. The model was created to predict the polymerization rate, polymer yield, and average molecular weights of polymer chains where the polymerization temperature changes from 40 to 90 °C. In developing polycentric kinetic models, there is a difficulty associated with evaluating the kinetic constants of the rates of elementary reactions/stages in polymerization. Each heterogeneous titanium–magnesium catalyst (TMC), including a co-catalyst, as well as an internal and an external electron donor, has its own set of kinetic parameters. Therefore, its kinetic parameters must be defined for each new catalyst. The presented algorithm for identifying the kinetic constants of rates starts with a kinetic model that considers one type of active centers. At the second stage, a deconvolutional analysis is used for the molecular weight distribution (MWD) of the gel permeation chromatography (GPC) data of the polypropylene samples and the most probable distribution of Flory chain lengths is found for each type of active centers. At the third stage, the single-center model is transformed into a polycentric kinetic model. For the catalyst system, five types of active centers were identified, together with a mass fraction and a number-average molecular weight for each active center type of the catalyst, which is consistent with the published results for similar Ti-based Ziegler–Natta catalysts.
Flexural Properties of Textile-Reinforced Concrete with Nonorthogonal Grids
Authors: Zhang Tianqi , Wang Boxin , Lu Xinyu , Guo Jiahuan
Published: November 2022

Textile-reinforced concrete (TRC) is a cement-based composite material that uses textile as a reinforcement material. The weft-direction fiber bundles in the traditional orthogonally arranged warp–weft textile hardly bear force, and its bonding strength with the weft fiber bundle is not ideal. Under the action of force, a small included angle between the stressed fiber bundle and the stressed direction can effectively increase the anchoring effect of their fibers in the matrix, resulting in higher bonding and reinforcement efficiency. To improve the utilization rate of fibers and the bonding strength between the textile and the concrete matrix, an arrangement along the diagonal of the grids was proposed in this paper. The flexural properties of basalt TRC plates with orthogonal grids (OG-BTRC) and plates with nonorthogonal grids (NOG-BTRC) with different grid angles and grid sizes with different laying methods, namely, a side layout (SL) and diagonal layout (DL), were studied through four-point bending tests. A comparative analysis was carried out with an ABAQUS simulation and the test results. The results showed that with a decrease in the grid angle, the BTRC specimens gradually showed a failure mode of multiple cracks, and most of the cracks appeared in the pure bending area; as the grid angle decreased, the BTRC specimens exhibited excellent flexural bearing capacity, good ductility, and high toughness. The total number of cracks on the specimen increased when it failed, while the spacing of the cracks decreased, and the fracture morphology appeared as fine and uniform features. The toughness of the specimen with a small grid angle using the DL laying method was greater than that using the SL laying method. The software simulation value matched the test data well, which proved that the test result was reliable.
Development of Double Hydrophilic Block Copolymer/Porphyrin Polyion Complex Micelles towards Photofunctional Nanoparticles
Authors: Karayianni Maria , Koufi Dimitra , Pispas Stergios
Published: November 2022

The electrostatic complexation between double hydrophilic block copolymers (DHBCs) and a model porphyrin was explored as a means for the development of polyion complex micelles (PICs) that can be utilized as photosensitive porphyrin-loaded nanoparticles. Specifically, we employed a poly(2-(dimethylamino) ethyl methacrylate)-b-poly[(oligo ethylene glycol) methyl ether methacrylate] (PDMAEMA-b-POEGMA) diblock copolymer, along with its quaternized polyelectrolyte copolymer counterpart (QPDMAEMA-b-POEGMA) and 5,10,15,20-tetraphenyl-21H,23H-porphine-p,p′,p″,p′′′-tetrasulfonic acid tetrasodium hydrate (TPPS) porphyrin. The (Q)PDMAEMA blocks enable electrostatic binding with TPPS, thus forming the micellar core, while the POEGMA blocks act as the corona of the micelles and impart solubility, biocompatibility, and stealth properties to the formed nanoparticles. Different mixing charge ratios were examined aiming to produce stable nanocarriers. The mass, size, size distribution and effective charge of the resulting nanoparticles, as well as their response to changes in their environment (i.e., pH and temperature) were investigated by dynamic and electrophoretic light scattering (DLS and ELS). Moreover, the photophysical properties of the complexed porphyrin along with further structural insight were obtained through UV-vis (200-800 nm) and fluorescence spectroscopy measurements.
Influence of Selected Crosslinking Agents and Selected Unsaturated Copolymerizable Photoinitiators Referring to the Shrinkage Resistance of Solvent-Based Acrylic Pressure-Sensitive Adhesives
Authors: Licbarski Adam , Bartkowiak Marcin , Czech Zbigniew
Published: November 2022

The properties of solvent-based pressure-sensitive adhesive (PSA) acrylics, especially shrinkage, are mostly determined by the type and amount of the crosslinking agent added to the prepolymer or by the crosslinking method. The shrinkage profiles of the selected solvent-based acrylic PSA coated on PVC film were investigated using metal chelates (between 0 and 0.55 wt.%), N-methylol acrylamide (up to 8 wt.%), polycarbodiimide and amino resins (up to 6 wt.%), diisocyanate (up to 1 wt.%), multi-functional propylene imines (up to 0.9 wt.%), conventional photoinitiators (up to 3 wt.%) and copolymerizable photoinitiators (up to 2 wt.%). These chemicals were both crosslinking agents that react after the solvent has been evaporated or at higher temperatures, and to the crosslinking agents that react under UV radiation. Some of them were copolymerizable, and others were added to the prepolymer before crosslinking. The best results of shrinkage (0.2%) were obtained by using the UV-crosslinking method and copolymerizable photoinitiators ZLI 3331 and ABP, as well as metal chelates AlACA and TiACA and multifunctional propylene imine Neocryl CX-100 (0.2%). Acceptable results were also achieved for amide BPIA (0.3%), benzophenone derivative PCB (0.4%), N-methylol acrylamide (0.35%) and benzoguanamine resin Cymel 1123 (0.45%).
Biodegradation of Chlorantraniliprole and Flubendiamide by Some Bacterial Strains Isolated from Different Polluted Sources
Authors: Fahmy Mohamed A. , Salem Samir H. , Qattan Shaza Y. A. , Abourehab Mohammed A. S. , Ashkan Mada F. , Al-Quwaie Diana A. , Abd El-Fattah Hassan I. , Akl Behairy A.
Published: November 2022

This study aimed to isolate, purify, and identify some bacteria from different sources known to be contaminated with pesticides and evaluate their ability to degrade two important pesticides, chlorantraniliprole (CAP), and flubendiamide (FBD). In our study, six isolates showed maximum growth in the presence of CAP and FBD in the growth media as a sole carbon source. The isolates were purified and then identified by biochemical and morphological tests, MALD-TOF-MS, and 16S rRNA techniques, as Bacillus subtilis subsp. subtilis AZFS3, Bacillus pumilus AZFS5, Bacillus mojavensis AZFS15, Bacillus paramycoides AZFS18, Pseudomonas aeruginosa KZFS4, and Alcaligenes aquatilis KZFS11. The degradation ability of studied bacterial strains against pesticides was estimated under different conditions (temperatures, pH, salt, and incubation time). The results reveal that the optimal conditions for all bacterial strains’ growth were 30–35 °C, pH 7.0, 0.0–0.5% NaCl, and an incubation period of 11 days at 150 rpm in the presence of diamide insecticides at 50 mg/L. The capacity of six bacterial strains of CO2 production and degradation ability against various diamide pesticides and other pesticide groups (Profenofos, Cypermethrin, Carbofuran, and Malathion) were evaluated. The results show that the Pseudomonas aeruginosa KZFS4 (LC599404.1) strain produced the highest CO2 content, about 1.226 mg CO2/16 day, with efficacy in the biodegradation of FBD-CAP (78.6%), while the absorbance of bacterial growth (OD 600) on various pesticides ranged from 1.542 to 1.701. Additionally, Consortium-(No. 3)-mix-6-strains gave 1.553 mg CO2/16 days with efficacy (99.6%) and turbidity of 2.122 to 2.365 (OD 600) on various pesticides. In conclusion, the six bacterial strains could play an important role in the biodegradation process of pollutants in soils.
Removal of Volatile Organic Compounds (VOCs) from Air: Focus on Biotrickling Filtration and Process Modeling
Authors: Rybarczyk Piotr
Published: November 2022

Biotrickling filtration is a well-established technology for the treatment of air polluted with odorous and volatile organic compounds (VOCs). Besides dozens of successful industrial applications of this technology, there are still gaps in a full understanding and description of the mechanisms of biotrickling filtration. This review focuses on recent research results on biotrickling filtration of air polluted with single and multiple VOCs, as well as process modeling. The modeling offers optimization of a process design and performance, as well as allows deeper understanding of process mechanisms. An overview of the developments of models describing biotrickling filtration and conventional biofiltration, as primarily developed and in many aspects through similar processes, is presented in this paper.
Adaptive Composite Fault Diagnosis of Rolling Bearings Based on the CLNGO Algorithm
Authors: Yu Sen , Ma Jie
Published: November 2022

In this paper, a novel composite fault diagnosis method combining adaptive feature mode decomposition (FMD) and minimum noise amplitude deconvolution (MNAD) is proposed. Firstly, chaos mapping and leader mutation selection strategy were introduced to improve the Northern Goshawk algorithm (NGO), and a chaotic leadership Northern Goshawk optimization (CLNGO) algorithm was proposed. The advantages of the CLNGO algorithm in convergence accuracy and speed were verified by 12 benchmark functions. Then, a new index called sparse pulse and cyclicstationarity (SPC) is proposed to evaluate signal sparsity. Finally, SPC is used as the fitness function of CLNGO to optimize FMD and MNAD. The optimal decomposition mode n and filter length of FMD, and filter length L and noise ratio ρ of MNAD are selected. The CLNGO-FMD is used to decompose signal into different modes. The signal is reconstructed based on the kurtosis criterion and the CLNGO-MNAD method is used to reduce the noise of the reconstructed signal twice. The experimental results show that the proposed method can achieve the enhancement of weak features and the removal of noise to extract the fault feature frequency adaptively. Compared with EMD, VMD, MOMEDA, MCKD and other methods, the proposed method has better performance in fault feature frequency extraction, and it is effective for the diagnosis of single faults and composite faults.
Financial Objectives and Satisfaction with Life: A Mixed-Method Study in Surf Lifestyle Entrepreneurs
Authors: O’Neill André , Dias Alvaro , Patuleia Mafalda , Pereira Leandro
Published: November 2022

Tourism lifestyle entrepreneurs (TLEs) have introduced an innovation in business management based on the region, community, environmental sustainability, and extra financial factors. This type of entrepreneur allows the development of regions by attracting investment and presenting innovative products/services and is an important aid to the local economy. Based on the importance of TLEs, this study aims to explore factors influencing satisfaction with life as a key ingredient to attracting surf TLE. For this purpose, priority was given to obtaining primary data through a sequential approach of mixed methods, first with a quantitative study using survey data of 109 surf TLEs, followed by in-depth interviews. The results show that a good contact network and a strong link to a place influence satisfaction with life in a positive way. As a result, the moderating effect of financial objectives on these relationships alerts destination decision-makers about different entrepreneurial approaches regarding surf businessman attraction. This study makes an important contribution by providing empirical evidence regarding the ongoing discussion about financial vs. non-financial objectives for this type of entrepreneur, showing that both are important for their decision-making process. These results provide valuable insights for several industry stakeholders, namely funders (for grant approval), policymakers (alerting that these entrepreneurs should be addressed considering non-financial objectives), and entrepreneurs (alerting to goal definition patterns).
The Role of the Accounting and Control Professional in Monitoring and Controlling Sustainable Value
Authors: Willekes Egbert , Wagensveld Koos , Jonker Jan
Published: November 2022

This study explains the role of the accounting and control professional in monitoring and controlling sustainable value. The general conclusion of our research is that the accounting and control professional should play a leading role in this process. Our findings explain how this role can be designed, state the current obstacles to implementing this role successfully, and indicate the necessary steps to deal with these obstacles. We argue that the most critical obstacle to implementing this crucial role is the current mindset of the accounting and control professional, which is mainly focused on financial value. We discuss the factors impacting the needed mindset change, distinguishing between internal and external factors. Our study is based on 13 parallel focus group discussions with 55 senior finance, sustainability, and strategic professionals. Our research responds to calls in the literature for further research on the role of the finance professional in sustainability accounting and control. It also contributes to the current academic discussion about management accounting and control, focusing on sustainability.
Modeling Permafrost Distribution Using Geoinformatics in the Alaknanda Valley, Uttarakhand, India
Authors: Pandey Arvind Chandra , Ghosh Tirthankar , Parida Bikash Ranjan , Dwivedi Chandra Shekhar , Tiwari Reet Kamal
Published: November 2022

The Indian Himalayan region is experiencing frequent hazards and disasters related to permafrost. However, research on permafrost in this region has received very little or no attention. Therefore, it is important to have knowledge about the spatial distribution and state of permafrost in the Indian Himalayas. Modern remote sensing techniques, with the help of a geographic information system (GIS), can assess permafrost at high altitudes, largely over inaccessible mountainous terrains in the Himalayas. To assess the spatial distribution of permafrost in the Alaknanda Valley of the Chamoli district of Uttarakhand state, 198 rock glaciers were mapped (183 active and 15 relict) using high-resolution satellite data available in the Google Earth database. A logistic regression model (LRM) was used to identify a relationship between the presence of permafrost at the rock glacier sites and the predictor variables, i.e., the mean annual air temperature (MAAT), the potential incoming solar radiation (PISR) during the snow-free months, and the aspect near the margins of rock glaciers. Two other LRMs were also developed using moderate-resolution imaging spectroradiometer (MODIS)-derived land surface temperature (LST) and snow cover products. The MAAT-based model produced the best results, with a classification accuracy of 92.4%, followed by the snow-cover-based model (91.9%), with the LST-based model being the least accurate (82.4%). All three models were developed to compare their accuracy in predicting permafrost distribution. The results from the MAAT-based model were validated with the global permafrost zonation index (PZI) map, which showed no significant differences. However, the predicted model exhibited an underestimation of the area underlain by permafrost in the region compared to the PZI. Identifying the spatial distribution of permafrost will help us to better understand the impact of climate change on permafrost and its related hazards and provide necessary information to decision makers to mitigate permafrost-related disasters in the high mountain regions.
Influence of Different Pretreatment Methods and Conditions on the Anaerobic Digestion Efficiency of Spent Mushroom Substrate
Authors: Lee Jongkeun , Ryu Do-yoon , Jang Kye Hwan , Lee Jong Wook , Kim Daegi
Published: November 2022

Consumption of mushrooms has recently increased due to their health benefits; consequently, increased mushroom cultivation generates large volumes of spent mushroom substrate (SMS) and effective methods for SMS valorization are thus required. Anaerobic digestion (AD) processes SMS with minimal energy and reduces the amount of waste generated; moreover, it contributes to energy generation through biogas production. To improve the energy efficiency of AD and promote sufficient biomass pretreatment, thermal pretreatment conditions require further investigation. Here, we evaluated the pretreatment efficiency and biogas production of the SMS thermal pretreatment process, studying different pretreatment temperatures to understand the formation of SMS degradation products and the changes in AD efficiency. Particularly, mechanical and hydrothermal pretreatment (HTP) methods were employed to improve SMS biodegradability. By increasing the substrate solubilization efficiency, HTP increased the biogas yield more effectively than mechanical pretreatment. Additionally, HTP improved the substrate’s physicochemical properties and increased the reactive surface area for microorganisms by changing the substrate morphology. Further, the biodegradability of the hydrothermally pretreated SMS was higher (87.46%) than that of the mechanically pretreated SMS (61.37%). Thus, SMS could be employed in biogas production and HTP play a key role in improving the biogas yield during SMS processing.
A Study of the Drivers of Decarbonization in the Plastics Supply Chain in the Post-COVID-19 Era
Authors: Zhao Changping , Sun Juanjuan , Zhang Yun
Published: November 2022

Plastics are an important basic material for national economic development. In the post-COVID-19 stage, green supply chain management has attracted widespread attention. In order to achieve carbon neutrality in the plastics industry, we explored the drivers of supply chain decarbonization in the plastics industry from a microlevel corporate supply chain perspective. Four primary factors and 21 subfactors were identified from the existing literature, and after validation by 12 experts, the causal relationships between the factors were analyzed using the Gray-DEMATEL method. The Gray-DEMATEL method was applied to analyze the causal relationships between the factors. The findings show that joint promotion by stakeholders is the most significant cause driver and market impact is the most prominent driver in the first-level indicator, both of which have a significant impact on low-carbon production. “Process optimization”, “Top-management support”, “Government regulations and support”, and “Information disclosure” are the most significant cause secondary drivers under the corresponding Tier 1 indicator factors, respectively, to provide realistic guidance for companies engaged in the plastics industry to continue to develop a low-carbon circular economy to achieve net-zero emissions under the challenges of COVID-19. Therefore, companies need to focus on the drivers of most importance in this work and understand the interplay between factors.
Enhancing the Logistics 4.0 Firms through Information Technology
Authors: Nour Redhwan
Published: November 2022

In the logistics service industry, the rapid advancement of Information Technology (IT) has cultivated a competitive dynamic that promotes uptake of logistics information technologies by Logistics Service Providers (LSPs). However, there remain many LSPs who have yet to embrace IT and thus have not realized their fullest competitiveness and financial success. This research conceptualizes the role of IT in logistics operations and investigates the degree to which IT, its usage, and its capabilities can affect LSP performance and competitiveness. The research interviews a logistics operations manager and the findings support that a firm’s performance and competitive advantage are influenced by IT usage and (especially) capability. As IT capability complements service processes and allows for innovation in services, this research and suggested future research provide not only theoretical and technological but also managerial implications.
Weather Influence on Native and Alien Mantis Dynamics and Their Abundance in the Current Climate Change Conditions
Authors: Pintilioaie Alexandru-Mihai , Filote Beatrice Daniela , Sfîcă Lucian , Baltag Emanuel Ștefan
Published: November 2022

Humans have traded and transported alien species for millennia, both with and without intention to spread them to new areas. Consistent knowledge of their ecology will allow decision makers to take suitable conservation actions, with the aim of avoiding threatening native species. Praying mantids (Mantodea) are predatory insects with a high impact on local invertebrates’ fauna. An alien mantis species (Hierodula tenuidentata) could create a disequilibrium in both the local ecosystem and in autochthonous mantid species (Mantis religiosa) if it can adapt to the local ecological conditions. Through this study, we reveal that the number of Hierodula tenuidentata individuals from an Eastern European Natura 2000 site was 7.6 times higher than the number of Mantis religiosa suggesting a higher density of the allochthonous species in the study area. According to a GLM analysis, the population of Mantis religiosa, measured from August to the end of October, declines more rapidly and is negatively influenced by the number of days from the first day of the year, while the population of Hierodula tenuidentata is influenced by local weather factors. This is the first study which analyzes the influence of local weather factors (namely air temperature, precipitation, daily atmospheric pressure, daily wind direction and speed, daily cloud cover, sunshine duration and number of days from the first day of the year) on the abundance dynamic of mantises in order to understand their ecology in the current climate change influence.
Evaluation of Common Prosperity Level and Regional Difference Based on the Background of Green Development
Authors: Ma Xiang-Fei , Zhang Ru , Ruan Yi-Fan
Published: November 2022

Green development and common prosperity are two major development goals put forward by the Chinese government. Based on the background of green development, the index system of common prosperity is designed in this paper, and the entropy method and coefficient of variation method are used to calculate the level of common prosperity in China from 2010 to 2020. The research findings are as follows: Firstly, the level of common prosperity based on the background of China’s green development has been raised from 2010 to 2020. The level of common prosperity based on the background of China’s green development has increased from 0.301 in 2010 to 0.513 in 2020. Secondly, based on the background of China’s green development, the level of common prosperity in the eastern region is higher than that in the northeast region, the northeast region is higher than that in the central region, and the central region is higher than that in the western region. Thirdly, the regional difference in common prosperity level based on the background of green development shows a trend of narrowing, with the coefficient of variation decreasing from 0.25 in 2010 to 0.13 in 2020. Finally, based on the research findings, corresponding suggestions are put forward to promote common prosperity.
Investigation of the DNA Damage and Oxidative Effect Induced by Venlafaxine in Mouse Brain and Liver Cells
Authors: Madrigal-Bujaidar Eduardo , Paniagua-Pérez Rogelio , Rendón-Barrón Michael Joshue , Morales-González José Antonio , Madrigal-Santillán Eduardo O. , Álvarez-González Isela
Published: November 2022

Venlafaxine is an antidepressant used worldwide. Therefore, studies to confirm its safe use are mandatory. This report evaluated the drug DNA damage capacity in the brain and liver of ICR mice, and its oxidative effect on DNA, lipids, and proteins, as well as the amount of nitrites, also in the brain and liver. Determinations were made at 2, 6, 12, and 24 h post-treatment, excluding DNA oxidation that was observed at 2 h. The tested doses of venlafaxine were 5, 50, and 250 mg/kg. The results showed DNA damage in the brain with the two more elevated doses of venlafaxine at 2 and 6 h post-treatment and also at 12 h in the liver. The comet assay plus the FPG enzyme showed DNA damage in both organs with all doses. The two high doses increased lipoperoxidation in the two tissues from 6 to 12 h post-administration. Protein oxidation increased with the three doses, mainly from 2 to 12 h, and nitrite content was elevated only with the high dose in the liver. The drug was found to affect both tissues, although it was more pronounced in the liver. Interestingly, DNA oxidative damage was observed even with a dose that corresponds to the therapeutic range. The clinical relevance of these findings awaits further investigations.
Maximizing Public and Private Satisfaction for a Better Privately Owned Public Space: The Case of Yeouido Business District
Authors: Manifesty Odilia Renaningtyas , Min Byunghak , Kim Seiyong
Published: November 2022

This paper proposes that balancing public and private satisfaction in the creation of privately owned public space (POPS) might be the key to producing more efficient and effective POPSs. Seven qualitative techniques categorized into on-site observations, space syntax, survey, and regulatory review were used to gather data, and triangulation methods were used to derive conclusions. We then discussed methods for improving POPS planning and designs that prioritize both public and private sectors by assessing the indirect and direct benefits of POPS. Indirect benefits are delivered when POPS can elevate the pleasantness of the surrounding environment. In this study, users and tenants of the host buildings were found to obtain the most benefits with their easy access to POPS, while the public saw the existence of POPS as insignificant compared to local parks. Furthermore, the lack of good designs resulted in low public interest and awareness. Although developers gain direct benefits from bonus FAR, a less rigid but more comprehensive system is needed to increase developer motivation to create better POPS. Proposals that combine two or more POPS and regulations that require connection to existing public open space networks should be considered in future.
Global Research Trend in Vaccine Design
Authors: Trivedi Dharmendra , Chaudhari Shanti P. , Bhatt Atul , Pathak Manohar
Published: November 2022

The current study established a research mapping of the vaccine design using bibliometric indicators and network visualization. For an analysis of the result, the study retrieved a total of 5379 documents from Scopus from 1983 to 2021. The study used the VOS Viewer and the RStudio tools for data visualization. The findings revealed that there has been significant growth in literature on vaccine design in the last two decades; in the last ten years, the year with the most publications were 2020, with 477 publications, and the highest had a total of 14,145 citations. D.R. Burton was ranked as the most prolific author, with 86 publications and 18,449 total citations and was observed as the most frequently published author in the domain. The National Institute of Health (NIH) was the most productive organization in the domain, with 266 publications. The document entitled “Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae” received a total of 1398 citations, and was the most cited document in the field of vaccine design. In network visualization, an analysis of the co-occurrence of keywords showed that “vaccine” and “vaccine design” occurred the most, which was 761 and 335 times, respectively. The study also observed that there were five clusters of author collaboration with a maximum of 18 authors and a minimum of two authors. The findings of the study will aid scholarly coalitions in the domains of medicine and health, information science and bibliometric professionals to carry out further research in the area of vaccine design.
Gender and Race-Based Health Disparities in COVID-19 Outcomes among Hospitalized Patients in the United States: A Retrospective Analysis of a National Sample
Authors: Pal Suman , Gangu Karthik , Garg Ishan , Shuja Hina , Bobba Aniesh , Chourasia Prabal , Shekhar Rahul , Sheikh Abu
Published: November 2022

COVID-19 has brought the disparities in health outcomes for patients to the forefront. Racial and gender identity are associated with prevalent healthcare disparities. In this study, we examine the health disparities in COVID-19 hospitalization outcome from the intersectional lens of racial and gender identity. The Agency for Healthcare Research and Quality (AHRQ) 2020 NIS dataset for hospitalizations from 1 January 2020 to 31 December 2020 was analyzed for primary outcome of in-patient mortality and secondary outcomes of intubation, acute kidney injury (AKI), AKI requiring hemodialysis (HD), cardiac arrest, stroke, and vasopressor use. A multivariate regression model was used to identify associations. A p value of <0.05 was considered significant. Men had higher rates of adverse outcomes. Native American men had the highest risk of in-hospital mortality (aOR 2.0, CI 1.7–2.4) and intubation (aOR 1.8, CI 1.5–2.1), Black men had highest risk of AKI (aOR 2.0, CI 1.9–2.0). Stroke risk was highest in Asian/Pacific Islander women (aOR 1.5, p = 0.001). We note that the intersection of gender and racial identities has a significant impact on outcomes of patients hospitalized for COVID-19 in the United States with Black, Indigenous, and people of color (BIPOC) men have higher risks of adverse outcomes.
Intratesticular Versus Intrafunicular Lidocaine to Reduce Perioperative Nociception and Immunological Response in Ponies Undergoing Field Castration
Authors: Vullo Cecilia , Crupi Rosalia , Di Paola Rosanna , Cuzzocrea Salvatore , Gugliandolo Enrico , Biondi Vito , Catone Giuseppe
Published: November 2022

The aim of this study was to evaluate the impact of intratesticular or intrafunicular lidocaine to reduce perioperative nociception and cytokine release in ponies undergoing field castration under total intravenous anaesthesia. Before castration, one group was injected with intrafunicular (FL) lidocaine and the other received intratesticular (TL) lidocaine. All ponies were premedicated with acepromazine (0.05 mg/kg) intramuscularly. Twenty minutes after the administration of acepromazine, xylazine (1 mg/kg) and butorphanol (0.02 mg/kg) were administered intravenously. Lidocaine 2% was given 1 mL/100 kg intrafunicularly in the FL groups or 2 mL/100 kg intratesticularly on each testicular side for TL. Surgery was performed by the same team of two experienced surgeons using Serra’s emasculator and an open technique was used for all ponies in order to promote postoperative drainage. In this study, we focused on the plasmatic levels of TNF-α and IL-6. The results from this study showed a significant difference in plasmatic concentrations of TNF-α and IL-6 between the two different locoregional anaesthetic protocols. Taken together, the results suggest that the intrafunicular lidocaine locoregional anaesthesia could be a useful technique in the anaesthesia protocol for field pony castration.
Adsorption of Cr(VI) by Mesoporous Pomegranate Peel Biowaste from Synthetic Wastewater under Dynamic Mode
Authors: Boutaleb Yassira , Zerdoum Radia , Bensid Nadia , Abumousa Rasha A. , Hattab Zhour , Bououdina Mohamed
Published: November 2022

This study aims to eliminate hexavalent chromium Cr(VI) ions from water using pomegranate peel (PGP) powder. Dynamic measurements are carried out to examine the influence of the operating factors on the adsorption efficiency and kinetics. The analyzed PGP is found to be amorphous with relatively high stability, contains hydroxyl and carboxyl functional groups, a pH of zero charge of 3.9, and a specific surface-area of 40.38 m2/g. Adsorption tests indicate that PGP exhibits excellent removal effectiveness for Cr(VI) reaching 50.32 mg/g while the adsorption process obeys the Freundlich model. The thermodynamic study favors the exothermic physical adsorption process. The influence of operating parameters like the flow rate (1 to 3 mL/min), bed height (25 to 75 mm), concentration (10 to 30 mg/L), and temperature (298 to 318 K) on the adsorption process are investigated in column mode. To assess the performance characteristics of the column adsorption data, a non-linear regression has been used to fit and analyze four different kinetic and theoretical models, namely, Bohart-Adams, Thomas model, Clark, and Dose response. The obtained experimental results were found to obey the Dose Response model with a coefficient of regression R2 greater than 0.977. This study proved the excellent efficiency in the treatment of chemical industry effluents by using cost-effect abundant biowaste sorbent. This research demonstrated great efficacy in the treatment of chemical industrial effluents by using an abundant, cost-effective biowaste sorbent, thereby achieving the UN SDGs (UN Sustainable Development Goals) primary objective.
A Comparison of Model Calculations of Ice Thickness with the Observations on Small Water Bodies in Katowice Upland (Southern Poland)
Authors: Solarski Maksymilian , Rzetala Mariusz
Published: November 2022

Small bodies of water in densely populated areas have not yet been thoroughly studied in terms of their ice cover. Filling the existing research gap related to ice cover occurrence is therefore important for identifying natural processes (e.g., response to climate warming and water oxygenation in winter), and also has socio-economic significance (e.g., reducing the risk of loss of health and life for potential ice cover users). This paper addresses the issue of determining the utility of two simple empirical models based on the accumulated freezing degree-days (AFDD) formula for predicting maximum ice thickness in water bodies. The study covered 11 small anthropogenic water bodies located in the Katowice Upland and consisted of comparing the values obtained from modelling with actual ice thicknesses observed during three winter seasons (2009/2010, 2010/2011, and 2011/2012). The best fit was obtained between the values observed and those calculated using Stefan’s formula with an empirical coefficient of 0.014. A poorer fit was obtained for Zubov’s formula (with the exception of the 2011/2012 season), which is primarily due to the fact that this model does not account for the thickness of the snow accumulated on the ice cover. Bengst’cise forecasting of the state of the ice cover and the provision of the relevant information to interested users will increase the safety of using such water bodies in climate warming conditions, reducing the number of accidents.
Berlin Devlet Kütüphanesi (Staatsbibliothek zu Berlin) Ms. Or. Oct. 3390 Numarada Kayıtlı Bir Şiir Mecmuasındaki Senâyî (Senâ’î) Mahlaslı Şiirler
Authors: TAŞKIN Gülşah
Published: November 2022

Şiir mecmuaları, divan tertip etmeyen ya da divanları henüz günümüze ulaşmamamış birçok şairin bilinmeyen şiirlerini barındırmaları nedeniyle Osmanlı edebiyat tarihi açısından birer hazine değerindedir. Berlin Devlet Kütüphanesi (Staatsbibliothek zu Berlin) Ms. or. oct. 3390 numarada kayıtlı bir şiir mecmuası da bu hazinenin önemli parçalarından birini oluşturmaktadır. Sözü geçen mecmuada, şimdiye kadar ortaya çıkmamış, Senâyî mahlaslı 28 şiire rastlanmıştır. 15-16. yüzyıllarda Senâyî (Senâ’î) mahlasını kullanan beş şair tespit edilmiştir. Bu şairlerin divanları elimizde olmadığı için şiirleri hakkında fazla bilgimiz bulunmamaktadır. Bu makalenin amacı, mecmuadaki 28 şiirin hangi Senâyî’ye ait olduğunu tespit etmek ve şiirleri gün ışığına çıkarmaktır. Makale dört ana bölümden oluşmaktadır. İlk bölümde 15-16. yüzyıllarda yaşamış Senâyî mahlaslı şairler hakkında bilgi verilmiştir. İkinci bölüm Berlin Devlet Kütüphanesi’ndeki mecmua ve mecmuanın müstensihinin kısaca tanıtımına ayrılmıştır. Üçüncü bölümde mecmuadaki 28 şiirin sahibinin kim olduğu tartışmaya açılmıştır. Dördüncü bölümde Senâyî’nin şiirlerine dair tespitlere yer verilmiş ve bahsedilen 28 şiirin transkripsiyonlu metinleri makalenin sonuna eklenmiştir.
Simulating the Yield Responses of Sugar Beet to Different Climate Change Scenarios by LINTUL-MULTICROP Model
Authors: YETİK Ali Kaan , KIZILDENİZ Tefide , ÜNAL Zeynep
Published: November 2022

Sugar beet is an essential crop for the sugar industry that have a very crucial role in agro-industry of Türkiye and Konya ranks first in terms of total sugar beet production and harvested area. The predictions, that the world's human population will reach 9 billion by the end of the current century and that demand for food will increase, are forcing farmers for the decision to search for new areas for agriculture or choose the crops that will be most productive in already cultivated lands. The aim of this study was to apply the LINTUL-MULTICROP Model for investigating the adaptation of sugar beet for the current climatic conditions and for climate change scenarios to show the response of sugar beet to an increase level of carbon dioxide and temperature. Four different scenarios were compared to check the effects of the climate change on sugar beet farming in the semi-arid Konya Region as followings: i) scenario (a) is the current climate conditions; ii) scenario (b) is the average temperatures increased 2 °C, iii) scenario (c) is 200 ppm increasing atmospheric CO2; iv) scenario (d) new optimum sowing and harvest dates in sugar beet farming and increased temperatures and atmospheric CO2 amount were simulated together. The optimum sowing and harvesting dates of sugar beet were moved 13 days back for sowing, and 8 days forward for harvesting. The highest yield was estimated under conditions of 2 °C and 200 ppm increased atmosphere temperature and CO2 levels with new sowing and harvest dates. The yields under irrigated conditions varied between 74.4 t ha-1 and 111.2 t ha-1. The irrigation water requirements of sugar beet were ranged from 618.8 mm to 688.5 mm for different scenarios. In conclusion, the cultivation of sugar beet tends to alter in semi-arid Konya environment.
Poligami dalam Keluarga Kristen Di Desa Haumeni
Authors: Selan Anthon Imanauel , Manu Mieke Yen
Published: November 2022

In Christianity, polygamy is rejected because the essence of Christian marriage is monogamy, which is sacred and holy because a holy God formed it. This study aims to describe the practice of polygamy that occurs in Christian families in Haumeni Village. The method used in this research was a qualitative approach; the sampling technique was purposive sampling, and in-depth interviews were the data collection techniques. The results showed that the subject's polygamous factors were heredity, economic factors, and the feelings of the husband, who had changed. The impact of polygamy can be seen in the emotions, psychological conditions, differences in treatment and closed social relationships felt by the wives. The first wife experiences heartache, disappointment, and loneliness because the husband tends to love and care more for the second wife, who is able to give him offspring and fulfill his husband's wishes.Meanwhile, the impact experienced by the second wife is that she does not have a clear legal status from the government or the church. In addition, the subject also did not involve the family and the church in their actions of polygamy. Before becoming a church member, the church has not maximally handled the issue of polygamy, which is an old tradition of the local community.
Abstrak: Dalam perspektif Kristen praktik poligami ditolak karena hakikat pernikahan Kristen adalah monogami yang sakral dan kudus sebab dibentuk oleh Allah yang Kudus. Penelitian ini bertujuan mendeskripsikan praktik poligami yang terjadi dalam keluarga Kristen di Desa Haumeni. Metode dalam penelitian ini adalah pendekatan kualitatif dan teknik samplingnya adalah purposive sampling. Teknik pengumpulan data dilakukan dengan wawancara mendalam. Hasil penelitian menunjukkan bahwa faktor berpoligami subjek adalah faktor keturunan, faktor ekonomi dan perasaan suami yang telah berubah. Adapun dampak praktik poligami terlihat dari perasaan, kondisi psikologis, perbedaan perlakuan dan hubungan sosial yang tertutup sangat dirasakan oleh para istri. Istri pertama mengalami sakit hati, kecewa dan kesepiaan karena suami cenderung lebih menyayangi dan perhatian pada istri kedua yang mampu memberinya keturunan dan memenuhi keinginan suami. Sedangkan dampak yang dialami oleh istri kedua adalah tidak memiliki status yang jelas secara hukum pemerintah maupun gereja. Selain itu, subjek juga tidak melibatkan keluarga dan gereja dalam tindakannya melakukan poligami. Gereja belum maksimal menangani persoalan poligami yang merupakan tradisi lama masyarakat setempat sebelum menjadi anggota gereja.
Mobilidade e precarização docente na região metropolitana do Rio de Janeiro
Authors: Assis da Silva Barbosa Gleyce
Published: November 2022

Este livro e seus respectivos capítulos exprimem as inúmeras abordagens do complexo teórico e metodológico que envolve a pesquisa acadêmica e a discussão de temas relacionados com a Formação Docente, o Ensino de Geografia e o Livro didático e que são fundamentais para a compreensão da Geografia Escolar. Foi organizado com a intenção de incentivar os novos pesquisadores por meio da publicação de seus artigos, ou seja, aqueles apresentados no XVIII ENANPEGE, em São Paulo, 2019, e fomentar ainda mais a rede com novas perspectivas de Formação Docente, do Ensino de Geografia e do Livro Didático em âmbito nacional, com a reunião de publicações de diversos grupos de pesquisas, em diferentes linhas de Ensino de Geografia nos Programas de Pós-Graduação em Geografia de Universidades localizadas em todas as regiões brasileiras.
Effect of Combination Miding Fern (Stenochlaena palustris) and Iron Tablet to Pregnant Women at Sintang Regency
Authors: Sari Nurmala , Eny Sunarsih  , Rohuna  , Aspia Lamana
Published: November 2022

Hemoglobin is one of the components of red blood cells to bind oxygen and then deliver oxygen to all body tissue cells. Lack of hemoglobin will cause anemia, which can increase the risk of morbidity in mother and baby. The purpose of this study was to analyze the effect of the combination of miding fern and iron tablets on hemoglobin levels in pregnant women in the Working Area of ​​the Nanga Ketungau Public Health Center, Sintang Regency. This research was a quantitative study. The population were all pregnant women in the 1st to 3rd trimester in the Working Area of the Nanga Ketungau Public Health Center, Sintang Regency, totaling 298 pregnant women. In this study used consecutive sampling technique. The total sample were 33 respondents. Results: The median value before the intervention was 11.20 g/dl and after the intervention it was 13.10 g/dl. The p-value was 0.000 where p<0.05. Conclusion: There is an effect of the combination of miding fern (Stenochlaena palustris) and iron tablets on the increase in hemoglobin levels in pregnant women in the Working Area of ​​the Nanga Ketungau Public Health Center, Sintang Regency.