bluuebunny/crossref_metadata_2025 huggingface dataset:
The specifics of building a psychological space for the use of information technologies as tools for activating the personal potential of university students
Authors: Shutenko Elena Nikolaevna , Shutenko Andrey Ivanovich , Vorotyntseva Daria  Alekseevna
Published: November 2022

The study is aimed at the development of the psychological-pedagogical construct of implementation the information technologies in higher education. The aim of the study is to determine the psychological conditions and logic of information technologies deployment to develop the personal potential of students. The authors use the methods of systematization and generalization, the method of conceptual-structural reconstruction, modeling and design, psychological testing and comparative analysis. As a result, presented the personal-oriented construction of ICT realization into the university training. It combines the principles of using ICT, the structure of educational communications and specific stimuli of ICT that activating the personal potential of students. The principles proposed in the construction serve as a psychological-pedagogical filter for the introduction of ICT (targeting, accessibility, redundancy, diversity, integrativity, sensitivity, synergy, refreshment, systematicity, scientific orientation, etc.). Compliance with these principles allows building on the basis of ICT a developed and psychologically correct system of educational communications, including such components as: didactic, information-gnostic, interactive, attractive-motivating, participating and other components. In the presented construction, the authors also offer a set of ICT stimuli that activate the personal potential of students: representative, exposing, adaptive, contact, search-heuristic, imprinting, control-evaluative, structuring, reflective, modeling, suggestive, translimitative, temporal, personalizing, inclusive, etc. Approbation this construction in the online learning showed the promise of its application in practice. The results of diagnostics using the self-actualization method (version of the POI test by E. Shostrom) showed that students have an increase in such indicators of personal potential as: self-support, self-regard and self-acceptance, as well as spontaneity, flexibility and productive relationship. The results obtained can be applied in the field of building student-centered digitalization practices of university education, the novelty of which lies in the indirect introduction of information technologies through the development of a variety of educational communications aimed at activating students' personal resources and capacities.
Assessment of differentiated models of care for stable patients on antiretroviral therapy in a tertiary health facility in Southwestern Nigeria
Authors: Akosile Christianah Temitope , Awogbemi Kayode Joshua , Opara Cyriacus Azuka
Published: November 2022

Objectives:

Differentiated care is a patient-centered care designed to improve quality of antiretroviral therapy (ART) service delivery. However, documenting patient experiences on models of differentiated care are critical to understanding and improving the models. This study assessed the preferences of patients on ART for differentiated care models and also explored the experiences of patients with the models.

Materials and Methods:

An in-depth interview was conducted on 30 patients on differentiated care models. Interviews were audio recorded, later transcribed, and combined with notes taken during the interview. Themes around preference for models, benefits, and challenges associated with models and subthemes were developed from the codes, verified, and analyzed using content analysis. Atlasti version 8 was used to code and develop themes from the data collected.

Results:

Participants expressed preferences for fast track model which is a facility-based model. They also reported that models yielded key benefits including reduced waiting time and cost of accessing drugs. The major negative impact reported by participants in community-based model was increased status disclosure risk and instability of program in the community pharmacies.

Conclusion:

Study participants living with human immunodeficiency virus and acquired immunodeficiency syndrome on differentiated care preferred facility-based models. Program instability and increased risk of status disclosure were major challenges associated with community-based model.
Beneficial effects of a polyherbal formulation in the management of sickle cell disease
Authors: Kola-Mustapha Adeola Tawakalitu , Amali Mohammed Otuofu , Atunwa Soliu Abiola , Ishola Ismail , Farayola Lawrence O. , Adeyeye Moji Christianah
Published: November 2022

Objectives:

Inflammation and pain among other comorbid conditions are prominent clinical complications associated with sickle cell disease (SCD). Despite significant improvement in the understanding of SCD pathophysiology, adverse effects of current treatment options are of great concerns. Faradin® (TD) is a polyherbal mixture used in the management of SCD. This study evaluates the acute toxicity, antinociceptive, and anti-inflammatory actions of TD.

Materials and Methods:

Acute toxicity study of TD was conducted according to test guidelines-423 of the Organization for Economic, Cooperation, and Development. Anti-inflammatory effect was assessed with carrageenan-induced paw edema and xylene-induced ear edema while antinociceptive effect was assessed using tail immersion, acetic acid-induced writhing, and formalin-induced nociceptive methods.

Results:

Oral administration of TD showed no acute toxic behavior. TD showed non-dose-related inhibition of inflammation in carrageenan- and xylene-induced edema when compared with vehicle-treated control. Post hoc analysis also revealed that TD caused significant increase in pain threshold in acetic acid, formalin, and tail immersion model of nociception. However, TD-induced antinociception was reversed by naloxone (opioid receptor antagonist) indicative of opioidergic system involvement.

Conclusion:

Findings from this study showed that TD has wide margin of safety and possessed anti-inflammatory as well as antinociceptive properties which lend credence to its potentials in the management of painful and inflammatory conditions associated with SCD.
Selecting the Regularization Parameter in the Distribution of Relaxation Times
Authors: Maradesa Adeleke , Py Baptiste , Hei Wan Ting , B. Effat Mohammed , Ciucci Francesco
Published: November 2022

Electrochemical impedance spectroscopy (EIS) is a characterization technique used widely in electrochemistry. Obtaining EIS data is simple when modern electrochemical workstations are used; however, analyzing EIS spectra is still a considerable quandary. The distribution of relaxation times (DRT) has emerged as a solution to this challenge. Nevertheless, DRT deconvolution underlies an ill-posed optimization problem, which is often solved by ridge regression (RR). RR’s accuracy strongly depends on the choice of the regularization level as encapsulated in the parameter λ. In this article, five cross-validation methods (i.e., generalized cross-validation, modified generalized cross-validation, robust generalized cross-validation, re-im cross-validation, and k-fold cross-validation) and the L-curve method are studied for the selection of λ. A hierarchical Bayesian DRT (hyper-λ) deconvolution method is also analyzed, whereby λ_0, a parameter analogous to λ, is obtained through cross-validation. The analysis of synthetic data suggests that the values of λ selected by generalized and modified generalized cross-validation are the most accurate among the methods studied. Furthermore, synthetic EIS spectra show that the hyper-λ approach outperforms optimal RR when λ_0 is obtained by generalized and modified generalized cross-validation. This research is expected to foster additional research on the central topic of regularization level selection for DRT analysis. This article not only explores various cross-validation methods, but also provides, through pyDRTtools, an implementation that may serve as a starting point for future research.
Coordination stoichiometry effects on the binding hierarchy of histamine and imidazole-M2+ complexes
Authors: Song Jake , Khare Eesha , Rao Li , Buehler Markus , Holten-Andersen Niels
Published: November 2022

Histidine-M2+ coordination is a recognized bond motif in biogenic materials with high hardness and extensibility, which has led to growing interest in their use in soft materials for mechanical function. However, the effect of different metal ions on the stability of the coordination complex remains poorly understood, complicating their implementation in metal-coordinated systems. Here, we use rheology experiments and density functional theory calculations to characterize the stability of coordination complexes and establish the binding hierarchy of histamine and imidazole with Ni2+, Cu2+ and Zn2+. We find that the binding hierarchy is driven by the specific affinity of the metal ions to different coordination states, which can be macroscopically tuned by changing the metal-to-ligand stoichiometry of the metal-coordinated network. These findings facilitate the rational selection of metal ions for optimizing the mechanical properties of metal-coordinated materials.
De-risking S–F bond formation: A gas cylinder-free strategy to access S(IV) and S(VI) fluorinated compounds.
Authors: Kordnezhadian Reza , Zogu Armir , Borgarelli Carlotta , Van Lommel Ruben , Demaerel Joachim , Ismalaj Ermal , De Borggraeve Wim
Published: November 2022

The sulfur-fluorine partnership occupies a privileged position in fluorine chemistry given the functional versatility that it imparts to organic structures. Despite this, available methodologies to forge S–F bonds are limited compared to C–F bond formation. Here, we describe a synthetic protocol that selectively enables the oxidative halogenation of aliphatic, aromatic, and heteroaromatic thiols to their corresponding SF4Cl, SO2F and SF3 derivatives. Selective oxidation of thiols to either S(IV)–F or S(VI)–F compounds is achieved by employing bench-stable calcium hypochlorite as chlorine surrogate (CLOgen), in the presence of KF as fluoride source. DFT calculations provided insight into the mechanistic aspects of the transformation and rationalized the observed isomeric preference towards the SF4Cl derivatives. Ultimately, this glovebox-free method selectively dispatches three classes of compounds upon reaction condition finetuning. Furthermore, first-in-class transformations are reported, including the preparation of aliphatic SF4Cl intermediates, their transformation into aliphatic sulfur pentafluoride analogs, and posttransformations that allow accessing highly complex SF4-bridged scaffolds.
A Dissipative Supramolecular Glue for Temporal Control of Amplified Enzyme Activity and Biocatalytic Cascades
Authors: Kamra Alisha , Das Sourav , Bhatt Preeti , Solra Manju , Maity Tanmoy , Rana Subinoy
Published: November 2022

Regulation of enzyme activity is key to the adaptation of cellular processes such as signal transduction and metabolism in response to varying external conditions. Synthetic molecular glues have provided effective systems for enzyme inhibition and regulation of protein-protein interactions. So far, all the molecular glue systems based on covalent interactions operated in equilibrium conditions. To emulate dynamic far-from-equilibrium biological processes, we introduce herein a transient supramolecular glue with controllable lifetime. The transient system uses multivalent supramolecular interactions between guanidium group-bearing surfactants and adenosine triphosphates (ATP), resulting in bilayer vesicle structures. Unlike the conventional fuels for non-equilibrium assemblies, ATP here plays the dual role of providing a structural component for the assembly as well as presenting active functional groups to “glue” enzymes on the surface. While gluing of the enzymes on the vesicles achieves augmented catalysis, oscillation of ATP concentration allows temporal control of the catalytic activities. We further demonstrate temporal activation and control of biocatalytic cascade networks on the vesicles, which represents an essential cellular component. Altogether, the temporal activation of biocatalytic cascades on the dissipative vesicular glue presents an adaptable and dynamic system emulating heterogeneous cellular processes, opening up avenues for effective protocell construction and therapeutic interventions.
Chiral Counteranion-Controlled Chemoselectivity in Gold-Catalysed Hydroamination/Enantioselective Formal 1,3-Allylic Alcohol Isomerisation of -Amino-1,4-enynols
Authors: Carli Lorenzo , Tapdara Anyawan , Jin Jianwen , Zhao Yichao , Chan Philip Wai Hong
Published: November 2022

A synthetic method for the preparation of 1,8-dihydroindeno[2,1-b]pyrroles and pyrrol-2-yl methanols in an enantioselective manner that relies on the chiral gold(I)-catalysed reactions of -amino-1,4-enynols is described. A divergence in product selectivity was achieved by exploiting the electrostatic interactions between the chiral counteranion of the metal catalyst and the substrate. With a gold(I) complex containing a chiral triflylamide-based counteranion, tandem dehydrative Nazarov-type electrocyclization/hydroamination of the substrate was found to selectively occur to afford the indeno-fused pyrrole adduct. In contrast, changing to a chiral phosphate-based counteranion was observed to result in a hydroamination/1,3-allylic alcohol isomerisation cascade pathway to give the 1H-pyrrole derivative.
Optofluidic Convection around Au Nanorods and Nanospheres by Photothermal Heating: Effect of Nanoparticle Geometry and Boundary Conditions
Authors: Borah Rituraj , Samantaray Millen , Kumar Ashish , Desai Anusha , Tseng Fan-Gang
Published: November 2022

Laser mediated heat transfer and optofluidic nano-scale convection can be exploited in the photothermal applications of plamonic nanoparticles in different micro-environment. In this work, heat transfer and fluid flow around Au nanospheres and nanorods in water medium under continuous and pulsed wave laser irradiance was investigated using an FEM based numerical framework. Au nanospheres of a wide range of diameter: 40 nm ≤ Diameter (D) ≤ 180 nm and nanorods with varying aspect ratio (1 ≤ Aspect ratio (A) ≤ 5) and orientation (0o ≤ θ ≤ 90o, ϕ = 0o, 90o) with respect to the incident EM radiation were investigated for continuous wave (CW) and pulsed wave laser. Relatively large Au nanorods dimensions similar to the models were also synthesized. The numerical results were validated by comparison with the experimental optical cross-section of the synthesized nanorods. It was found that although nanorods can attain much higher temperature than nanospheres, orientation of a nanorod is an important factor to be carefully considered in applications. In micro-scale spherical and hemispherical confinements (diameter < 14.4 μm) convective velocity fields around nanoparticles were determined for slip and no-slip condition on the confining walls. It was found that slip boundary condition on the confining walls has a moderate effect on the strength of the flow field. While, the effect of the proximity of the nanoparticle from the walls is considerable.
Influence of transition metal electron configuration on the structure of metal-EDTA complexes
Authors: Foreman Madison M. , Alessio Maristella , Krylov Anna I. , WEBER J. Mathias
Published: November 2022

The vibrational spectra of cold complexes of ethylenediaminetetraacetic acid (EDTA) with transition metal dications in vacuo show how the electronic structure of the metal provides a geometric template for interaction with the functional groups of the binding pocket. The OCO stretching modes of the carboxylate groups of EDTA serve as structural probes, informing on the spin state of the ion as well as the coordination number in the complex. The results highlight the flexibility of EDTA in accepting a large range of metal cations in its binding site.
UnCorrupt SMILES: a novel approach to de novo design
Authors: Schoenmaker Linde , Béquignon Olivier J. M. , Jespers Willem , van Westen Gerard J. P.
Published: November 2022

Generative deep learning models have emerged as a powerful approach for de novo drug design, as they aid researchers in finding new molecules with desired properties. Despite continuous improvements in the field, a subset of the outputs that sequence-based de novo generators produce cannot be progressed due to errors. Here, we propose to fix these invalid outputs post hoc. In similar tasks, transformer models from the field of natural language processing have been shown to be very effective. Therefore, here this type of model was trained to translate invalid Simplified Molecular-Input Line-Entry System (SMILES) into valid representations. The performance of this SMILES corrector was evaluated on four representative methods of de novo generation: a recurrent neural network (RNN), a target-directed RNN, a generative adversarial network (GAN), and a variational autoencoder (VAE). This study has found that the percentage of invalid outputs from these specific generative models ranges between 4 and 89 %, with different models having different error type distributions. Post hoc correction of SMILES increases model validity, with the SMILES corrector fixing 35 to 80 % of invalid model outputs. While, corrector models trained with one error per input sequence alter 60 to 90 % of invalid inputs, a higher performance was obtained for transformer models trained with multiple errors per input. In this case, the best model was able to correct 60 to 95 % of invalid generator outputs. Further analysis showed that these fixed molecules are comparable to the correct molecules from the de novo generators with regard to novelty and similarity. Additionally, the SMILES corrector can also be used to expand the amount of interesting new molecules within the targeted chemical space. Introducing different errors into existing molecules yields novel analogs with a uniqueness of 39 % and a novelty of approximately 20 %. The results of this research demonstrate that SMILES correction is a viable post hoc extension and can enhance the search for better drug candidates.
Mathematical model of the snow mass transportation process in the snowblower rotor
Authors: Aleshkov D. S. , Korchagin P. A. , Teterina I. A.
Published: November 2022

Introduction. The complexity and laboriousness of determining the functional dependencies between the structural elements of a rotary snowplow and the developed snow mass when conducting experimental studies on a physical model of a rotary snowplow necessitates the development of mathematical models that make it possible to describe as accurately as possible the processes of interaction between the elements of a rotary snowplow and snow mass. The method of research. A mathematical model of the process of transporting snow mass in a rotor, in which snow is represented as a loose medium, including a set of individual particles, was developed using the method of discrete elements. When constructing a mathematical model, the problems of identifying mass and surface forces acting in the ‘rotor - snow mass’ system were solved. The principle of the location of a group of particles in the interblade space of the snowplow rotor and the choice of the method for analyzing the mathematical model are substantiated.Results. The implementation of this mathematical model on a computer made it possible to obtain the numerical values of the forces of the normal reaction of the rotor casing at each moment of time, which allows developing new and improving existing design schemes, reasonably choosing the design and technological parameters of the rotor of a snow blower.Discussion and conclusion. The proposed mathematical model and the equations of motion, compiled on its basis, make it possible to unambiguously determine the values of all forces acting on the snow mass during its transportation in the rotor of a rotary snowplow. The model under consideration makes it possible to simulate a snow mass in the interblade space of a more complex configuration and a set of particles that have an irregular distribution in size and relative position.
Factors affecting financial investment decisions: undergraduate student context
Authors: Hidayat Febrian Satria , Hartono Ulil
Published: November 2022

Investment decisions are decisions to allocate funds into firms of investment that will generate higher profits in the future. This study aims to examine factors affecting financial investment decisions in undergraduate student context. Undergraduate students become interesting to investigates since they started investing their monthly income. This study employs quantitative research and the structural equation model analysis method. A total of 230 undergraduate students responded to the survey. The findings of the study indicate that there are several factors which significantly affect student financial investment decision which are financial literacy, financial attitude, regret aversion bias, and herding. Risk tolerance does not influence student investment decision. Thus, this study implies the importance financial service institutions roles and universities in educating and providing insight to potential investors, i.e., undergraduate students. Efforts to improve investment decisions from an early age are essential since increasing the amount of investment is beneficial for a country's economy.
The effect of abusive supervision on employee silence with the mediation role of emotional exhaustion and moderate leader-member exchange
Authors: Sridadi Ahmad Rizki , Admojo Rifki Tri Cahyo , Himmawan Muhammad Fikri , Fuciu Mircea
Published: November 2022

Employee silence is a phenomenon in the workplace where an employee withholds all ideas and information, triggered by emotional exhaustion resulting from negative affectivity, such as abusive supervision in the workplace. The leader-member exchange level also affects employees' intensity when holding back all ideas and information they have at work. This study aims to determine the effect of abusive supervision on employee silence, mediated by emotional exhaustion and the moderating effect of leader-member exchange. The variables used in this study are abusive supervision, employee silence, emotional exhaustion, and leader-member exchange. This study used quantitative methods and questionnaires as data collection tools and analysed it using PLS. One hundred PT. XYZ’s employees participated in this study as the respondent. This study shows that abusive supervision significantly affects employee silence and emotional exhaustion. Emotional exhaustion partially mediates the impact of abusive supervision on employee silence, and leader-member exchange does not moderate the effect of abusive supervision on emotional exhaustion. The novelty of study leverages employee emotional exhaustion instead of organizational politics to mediate the relationship between abusive supervision and employee silence.
Формирование симметричного вторичного упаковочного мотива как причина кристаллизации энантиочистого ментанилсульфона с двумя независимыми молекулами
Authors: Герасимова Д.П. , Гильфанов И.Р. , Павельев Р.С. , Никитина Л.Е. , Лодочникова О.А.
Published: November 2022

На основе данных рентгеноструктурного анализа установлена тенденция нового соединения – энантиочистого ментанилсульфона – кристаллизоваться с двумя независимыми молекулами в ячейке, геометрия которых имеет полное подобие в части молекулы, несущей хиральные центры, и имеет существенное расхождение в части, содержащей прохиральные группы – сульфонильную и метиленовые. Конформационные подвижки прохиральной части независимых молекул обеспечивают формирование псевдоцентросимметричного вторичного упаковочного мотива в хиральном кристалле.
ANALYSIS OF METHODS FOR DATA CONFIDENTIALITY ENSURING DURING TRANSMITTING FROM UAV
Authors: Gnatyuk Sergiy , Kinzeryavyy Vasyl , Polishchuk Yuliia , Nechyporuk Olena , Horbakha Bohdan
Published: November 2022

The rapid development of unmanned aerial vehicles (UAVs), as well as the expansion of the list of actions performed by modern UAVs, led to increased requirements for the safety and reliability of data transmission. In the context of warfare, when confidential information is collected, the protection of such information is a top priority. The practical level of conducting aerial reconnaissance during current warfare demonstrates the urgent need to create UAV which capable of performing flight tasks and aerial reconnaissance in the mode of installed radio interference, and also emphasizes the importance of ensuring the data confidentiality about target objects transmitted by an optical channel for the implementation of their processing in automated systems. The paper provides a review and comparative analysis of modern cryptoalgorithms that are used to ensure data confidentiality during their transmission by radio channel from UAV to ground objects. There are the system of criteria (multi criteria analysis) was used to compare following cryptographic algorithms (similar to AES, NESSIE, etc competitions): block and key sizes; modes of operation; encryption speed; memory requirements; resistance (security) to cryptanalysis. The conducted analysis showed that each cryptographic algorithm has advantages and disadvantages. Also, there is no universal cryptographic algorithm that capable to resolve all privacy problems in UAV. According to the limited resources in the process of UAV operation, it is necessary to create a universal set (dataset) of cryptographic algorithms that could solve various problems in different conditions including different aspects of UAV exploitation. It is these studies that will be devoted to the further work of the authors within the framework of the ongoing scientific project.
IMPROVEMENT OF THE CYBER PROTECTION OFTHE ARMED FORCES TAKING INTO ACCOUNT THE EXPERIENCE OF COUNTERING MILITARY CYBER ATTACKS OF THERUSSIAN FEDERATION IN 2022
Authors: Baidur Oleksii
Published: November 2022

The article considers the possibilities of improving the cyber defense system of the Armed Forces of Ukraine and the Ministry of Defense of Ukraine in accordance with the goals and objectives defined in the decisions of the National Security and Defense Council of Ukraine and the Laws of Ukraine. A review of the requirements of normative documents on information and cyber security of Ukraine and similar documents of the United States of America was carried out. The considered algorithm for developing a risk management system in the direction of information security is outlined in the USA national standards. The scientific novelty of the work is that in the process of developing the risk management system in the information and communication systems (ICS) of the Armed Forces of Ukraine and the Ministry of Defense of Ukraine, it was proposed to create an decision support system that will be based on a specialized knowledge base capable of accumulating experience both during cyber-defense measures of the ICS and during the implementation of cyber-influences on the ICS of the enemy. An overview of open international standardization methods and relevant knowledge bases that can be used to update information on vulnerabilities and countermeasures in IC systems was carried out. The joint to use of open knowledge bases and specialized knowledge bases potentially can create new opportunities not only during cyber defense, but also during the implementation of cyber influences on the ICS of the enemy, therefore, this direction of research is promising and corresponds to the national interests of Ukraine
PROSPECTIVE DIRECTIONS OF TRAFFIC ANALYSIS AND INTRUSION DETECTION BASED ON NEURAL NETWORKS
Authors: Ilyenko Anna , Ilyenko Sergii , Kravchuk Iryna , Herasymenko Marharyta
Published: November 2022

The main problems of the network security at the moment are the difficulty of combining existing systems from different vendors and ensuring their stable interaction with each other. Intrusion detection is one of the main tasks of a proper level of network security, because it is they who notify about attacks and can block them when detected. Today, monitoring and analyzing the quality of traffic in the network, detecting and preventing intrusions is helped by IDS systems and IDS systems of the new generation IPS. However, they have been found to have certain drawbacks, such as the limitations of signature-based systems, as static attack signatures limit the flexibility of systems and pose the threat of missing detection of other attacks not entered into the database. This gives rise to the creation of more and more new hybrid systems, but the challenge is to ensure their efficiency and flexibility, which is helped by the use of artificial neural networks (ANNs). This paper considers ways to improve the use of the convolutional neural network model itself by means of modified processing, data analysis, the use of Softmax and FocalLoss functions to avoid the problem of uneven distribution of sample data by the ratio of positive and negative samples, based on training using the KDD99 dataset. The article provides practical examples of possible integration of IDS and ANN systems. Combinations of backpropagation neural networks and radiant-basis neural networks, which showed some of the best results and proved that the combination of networks helps to increase the efficiency of these systems and create a flexible network adjusted to the needs and requirements of the systems. Although the use of artificial neural networks is a popular tool, it has identified a number of disadvantages: critical dependence on the quality of the dataset, which pours both the quality of networking and the amount of data (the more data, the better and more accurate the network training). But if the data is excessive, there is a chance of missing such implicit, but also dangerous attacks as R2L and U2R.
Második generációs antihisztaminok biztonságosságának összehasonlító vizsgálata földi és barokamrában szimulált repülési környezetben
Authors: Reményi Ákos , Grósz Andor , Szabó Sándor András , Molnár Dávid , Helfferich Frigyes
Published: November 2022

A népbetegséggé vált allergiás nátha, valamint a kezelésében alkalmazott antihisztaminok lehetséges mellékhatásaként létrejövő álmosság és kognitív funkció csökkenés komoly probléma a közlekedésben – különösképpen a professzionális repülésben – résztvevők és a biztonsági szempontból kritikus munkakörökben dolgozók számára. Mára rendelkezünk földi körülmények között terápiás dózisban alkalmazva a napi aktivitást a szedáció szempontjából nem befolyásoló antihisztaminokkal. A dolgozatban bemutatott vizsgálat annak megismerését célozta, hogy a repülés során további körülményként, a magasságtól függően a szervezetben hypoxiás alkalózist okozó hypobáriás hypoxia ezt a biztonságosságot rontja-e? A vizsgálat randomizált, placebo kontrollált, kettős vak, keresztezett módon 33 önkéntes, egészséges felnőttön, földfelszínen, illetve szimulált 4000 méteres magasságnak megfelelő körülmények között hasonlította össze a cetirizin és a bilasztin hatását a rövid távú memóriára, a megosztott figyelemre és a monotóniatűrésre, valamint a résztvevők önértékeléssel mért éberségi szintjére. Az adatokat paraméteres és nem-paraméteres statisztikai eljárásokkal, továbbá sztochasztikus szimulációval kerültek feldolgozásra.
A humán herpesz vírus 3 (HHV-3) okozta fertőzés – herpes zoster – fizioterápiás kezelési lehetősége
Authors: Deli Mária , Sandra Sándor
Published: November 2022

A herpes zoster (övsömör) napjainkban is gyakran előforduló megbetegedés. A gyógyszeres kezeléssel párhuzamosan a fizioterápia alkalmazása is hatékony megoldást jelenthetne erre a kórképre. Az esetek jelentős részében ugyanakkor nem alkalmazzuk ezt a terápiás lehetőséget. Szakterületünk igen sok esetben sikeresen alkalmazta az övsömör különböző szövődményeinek kezelése során. Eredményeink gyakran igen látványosak voltak és a bőrelváltozások, valamint a fájdalom időtartalma is jelentősen lerövidült. Ezért minden esetben javasoljuk a fizioterápia aktívabb kihasználását ezen betegségek kezelése során. A szerzők ismertetik a humán herpesz vírus 3 által okozott betegségek klinikumát, kórlefolyását, terjedési módját, főbb szövődményeit, a vírus reaktiválódását elősegítő tényezőket, valamint a lokális és szisztémás terápia leírása után részletesen ismertetik a különböző fizioterápiás kezelési lehetőségeket.
Application of Fermented Feed Technology and Semi-Intensive Pig Farming System in the Women's Farmer Group "Suka Nadi" Pejarakan Village, Gerokgak District, Buleleng Regency
Authors: Yan Tonga  , I Gede Sutapa  , I Ketut Agung Sudewa
Published: November 2022

Bali pig is one of the meat-producing livestock commodities that has great potential to be developed because it has beneficial properties and abilities, but its presence on the island of Bali has begun to decline and is only found in certain areas such as in Buleleng, Karangasem, and Klungkung Regencies. Bali's pig population in Bali Province from 2017-2019 decreased by 27.51%. Likewise, it also occurs in Buleleng Regency by 26.09% and in Pejarakan Village, Gerokgak District, Buleleng Regency by approximately 50%. Some of the factors that influence this decline include feed management and the farming system. Likewise, related to the provision of animal feed ingredients derived from food crops such as corn, bananas, and peanuts, the partners have not really understood in an effort to increase the productivity of these food crops as animal feed.  Based the enormous potential and opportunity for Balinese pigs and felt very profitable by the Suka Nadi Peasant Women's Group (KWT) in Pejarakan Village which is located 145 km from the provincial capital with a total of 28 members now still doing Balinese pig farming business on a small scale/household even though it experiences a mortality rate of 25% because in its maintenance it is still with an extensive farming system and makeshift feed. The death of the livestock is caused by being crushed by the mother and getting sick because the livestock lacks the nutrients and feed provided. The problem is that partners do not really understand efforts to increase the productivity of Bali pig livestock, especially regarding the management of the provision and feeding of their livestock. The solution provided is to provide an understanding of knowledge and skills about efforts to increase the productivity of local pig livestock, especially regarding the management of the provision and feeding with fermented feed technology and efforts to increase the productivity of food crops as animal feed ingredients. The method were surveys, interviews, discussions, counseling/training in theory and practice as well as monitoring and evaluation. The output produced is that partners have understood about efforts to increase the productivity of Bali pigs and food crops (corn) as animal feed ingredients and are able to make fermented animal feed so that the provision of feed is more quality, effective and efficient and the partners have a place to make small-scale fermented feed/households.
The Role of Democratization and Economic Freedom on Corruption: A Case study of ASEAN
Authors: Abbas Muhammad Hasyim Ibnu , Kustiandi Januar , Syaifudin Amin , Nurdiono Achmad
Published: November 2022

This study aims to determine the interaction effect of democracy and economic freedom on corruption in ASEAN, 2012-2021. The tool analysis used in this study is typology analysis to determine the position of each ASEAN country based on the level of Corruption, democracy, and economic freedom, and it was amplified by panel data regression with a fixed effect. Typology analysis shows that the higher the level of democracy and economic freedom, the better the Corruption Perception Index (CPI). Regression analysis also shows that when a country possesses economic freedom level below 6.25, then democracy has a negative effect on corruption. Likewise, when the level of democracy of a country is below 4.4 then a change of economic freedom will reduce the CPI instead. This corresponds to the typology analysis in which Malaysia and Singapore have levels of democracy and economic freedom over 4.4 and 6.25”on average”during 2012-2021.
Predicting Mobile Game Adoption: Integrating Game Features and Theory of Planned Behavior
Authors: Gaffar Mohammad Rizal , Rafdinal Wahyu , Susanto Eko , Juniarti Cahaya
Published: November 2022

This study investigates gamers' behavior in adopting mobile games by integrating game features and the theory of planned behavior (TPB).  This study used 408 samples of Indonesian gamers. A partial least square is applied to examine the influence among subjective norm, perceived behavioral control, attitude, game features, and intention to play mobile games. The results show that the integration between Game features and TPB gives a deeper explanation of gamers' behavior in adopting mobile games. Considering the factors in gamers' behavior, this study's results give the base to formulate an implementation strategy for the appropriate game features in attracting gamers' interest to keep playing mobile games. It is also the first study that integrates Game features and TPB to assess mobile game adoption.
Pengaruh Berbagai Konsentrasi Pupuk Organik Cair Guano terhadap Pertumbuhan dan Hasil Tanaman Bawang Merah (Allium ascalonicum L.) Asal Biji
Authors: Haq Hasriani Rizki , Bambang Budi Santoso  , Dwi Ratna Anugrahwati
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh berbagai konsentrasi pupuk organik cair guano terhadap pertumbuhan dan hasil tanaman bawang merah (Allium ascalonicum L.) asal biji. Penelitian dilaksanakan pada Februari - Mei 2022 di Kelurahan Pagesangan, Kota Mataram. Rancangan percobaan yang digunakan adalah rancangan acak lengkap satu faktor dengan 6 perlakuan yaitu 0 ml/l Pupuk Organik Cair (POC) guano, 50 ml/l POC guano, 100 ml/l POC guano, 150 ml/l POC guano, 200 ml/l POC guano, dan 250 ml/l POC guano. Perlakuan diulang sebanyak 4 kali dan setiap ulangan terdiri atas 4 seri perlakuan sehingga terdapat 96 unit percobaan. Data yang diperoleh dianalisis menggunakan analisis keragaman pada taraf nyata 5% kemudian dilanjutkan dengan uji lanjut Tukey’s HSD (Honestly Significant Difference) menggunakan program costat. Hasil penelitian menunjukkan bahwa pemberian POC guano dengan konsentrasi 50-250 ml/l pada budidaya tanaman bawang merah asal biji berpengaruh tidak nyata terhadap parameter pengamatan seperti tinggi tanaman, jumlah daun, panjang akar, bobot berangkasan basah, dan bobot berangkasan kering, jumlah umbi, diameter umbi, bobot basah umbi, dan bobot kering umbi.
Protótipo de Esteira Seletora Semi-Automatizada a Partir do Arduino
Authors: Angelini Carlos Eduardo , Cavalari Igor Guilherme , Ribeiro Fernando Sabino Fonteque , Almeida João Paulo Lima Silva
Published: November 2022

Os avanços da automação industrial vêm proporcionando aprimoramentos em processos industriais, contribuindo com o aumento de diversos indicadores de desempenho. Um dos elementos presentes nestas tecnologias são as esteiras seletoras automatizadas, que compõem processos de manufatura em diversas demandas. Neste sentido, o estudo de sistemas automatizados em instituições de ensino é de grande relevância para que estudantes e pesquisadores tenham contato com tais tecnologias. Neste artigo é proposto um protótipo de uma esteira seletora semi-automatizada a partir de uma placa Arduino e componentes compatíveis. O protótipo deve servir como objeto de estudo para futuros estudantes e pesquisadores da área de automação de processos industriais. Seu funcionamento consiste em uma lógica condicional para que o sistema detecte a altura de objetos durante o transporte e pare a rolagem da esteira caso passe um objeto de altura indesejada. A retirada do objeto de altura indesejada deve ser de forma manual, porém, o protótipo foi desenvolvido de tal forma a facilitar a integração com outros elementos, principalmente devido aos dispositivos utilizados. Ao fim do projeto, o protótipo apresentou-se funcionando plenamente, cumprindo seu propósito inicial.
Modelagem e Análise da Resposta de um Circuito RC via Arduino/Simulink
Authors: Camargo Lucas Carvalho de , Bispo Vitor Hugo De Souza , Possoli Felipe Augusto de Aguiar , Soares Jefferson Wilhelm Meyer , Breganon Ricardo , Alves Uiliam Nelson Lendzion Tomaz
Published: November 2022

A modelagem matemática é uma ferramenta valiosa na análise e no projeto de diferentes sistemas. Após a modelagem, a comparação dos dados experimentais com a simulação de tais modelos é um importante processo para verificar o comportamento dos sistemas e a consonância do modelo obtido com a realidade. Neste trabalho busca-se apresentar a modelagem, simulação e comparação com os dados experimentais de um circuito RC para a verificação e a validação do modelo matemático obtido. A ferramenta utilizada para realizar a simulação, comunicação para obtenção dos dados, e o tratamento dos mesmos foi o Matlab/Simulink®. O experimento realizado contou com um Arduino UNO, responsável por amostrar os dados do circuito e fornecer a tensão de entrada ao sistema. O circuito RC estudado é composto por: três resistores, e um capacitor. Os resultados encontrados mostram a coerência do modelo com os dados experimentais, e que essa abordagem pode ser usada em aulas de diversas disciplinas que envolvam circuitos e modelagem de sistemas.
DISCIPLINA POSITIVA: UMA ABORDAGEM PRÁTICA-FILOSÓFICA EM SALA DE AULA
Authors: Barros Cleidejane Soares de , Barros Betijane Soares de , Lima Mariana Almeida de , Mata Claudenice Santos Vercosa , Jambo Eduardo Jorge de Almeida , Jacinto Luciano Canudo
Published: November 2022

A Disciplina Positiva, por ser um método inovador de educar, sem a utilização do sistema
punitivo ou de recompensa, tem atraído o olhar dos educadores. Na presente pesquisa, a análise
é da disciplina positiva direcionada para professores e seu impacto na sala de aula. A pesquisa
analisou produções científicas publicadas entre 2015 e 2021, nos sites: BVS, Scielo, Periódicos
da Capes, Wiley, PubMed e Science Direct. Os objetivos deste estudo é identificar o avanço da
produção científica no meio acadêmico através da bibliometria. Trata-se de uma compilação de pesquisa do estudo bibliométrico. Utilizando os descritores estruturados no DeCS e MeSH. O período de coleta dos dados correu no mês de junho de 2021. Foi utilizado como critério de
inclusão artigos científicos relacionados ao tema e, como critérios de exclusão, artigos científicos que não contemplam a temática sobre disciplina positiva. Deste modo, conclui-se que a Disciplina Positiva é um método essencial e inovador na educação de crianças, seja no ambiente escolar ou familiar.
PSICOLOGIA EM CONTEXTO DE CRISE: vivências durante a pandemia covid-19
Authors: Lima Amanda de Oliveira , Santos Maycon Guimarães , Freitas Camila Siqueira Cronemberger , Batista Rose Danielle de Carvalho
Published: November 2022

Nos últimos dois anos vivemos um percurso singular na história que
transformou a forma de ver, vivenciar e estar diante das coisas, das pessoas e
dos acontecimentos. O período pandêmico trouxe consigo a necessidade de
reajustamento em todos os âmbitos da vida, de modo que todos sofremos os
impactos de diferentes maneiras.
A saúde mental, neste contexto, foi um dos meandros afetados pela
pandemia, uma vez que o distanciamento físico, o medo da contaminação, a
obrigatoriedade de mudança de hábitos, o luto, dentre outros pontos, estiveram
presentes de maneira acentuada durante este período. Por conta disto, a
atuação do psicólogo precisou de adaptações e transformações durante este
caminho, de modo a atender sobretudo as pessoas e os grupos em sofrimento
psicológico.
Com o objetivo de reunir as práticas dos psicólogos nas diversas áreas
de atuações, convidamos profissionais que desenvolveram ações de destaque
no transcurso da pandemia, com o propósito de apresentar as experiências,
publicizá-las e, ainda, servir de apoio a estudos e pesquisas posteriores. Esta
coletânea servirá, também, como material com conteúdo acerca da história
do fazer psicológico neste momento tão difícil vivenciado pela humanidade.
Neste sentido, este livro “Psicologia em contexto de crise: vivências
durante a pandemia covid-19” reúne 11 capítulos com discussões acerca do
fazer do/a psicólogo/a, com a descrição das práticas realizadas nas áreas de
psicologia social comunitária, psicologia escolar educacional, psicologia clínica,
psicologia hospitalar e psicologia organizacional.
Lei da Representação na Economia Divina
Authors: Kloppenburg Boaventura
Published: November 2022

O conceito de «representação», aqui, é estudado do ponto de vista teológico no relacionamento do homem com Deus ou no encontro de Deus com o homem. Pois neste ponto coincidem as experiências das religiões naturais com os dados da Revelação Divina: que normalmente não se dá um relacionamento imediato, direto e puramente pessoal do homem com Deus: o homem chega a Deus através de outros como mediadores, sacerdotes ou representantes; e que, por outro lado, também Deus costuma servir-Se de mediadores e representantes Seus para manifestar-Se aos homens, convidá-los à comunhão conSigo e nela os receber. A mediação parece ser norma fundamental da ação divina e do nosso relacionamento com Deus. É esta a conclusão mais evidente e importante do longo estudo de Josef Scharbert sôbre o Antigo Testamento e o Antigo Oriente?
Um estudo do crucifixo de Padova de Giotto di Bandone
Authors: Schneider Talise Adriele Teodoro , Nunes Meire Aparecida Lóde , Souza Thais Regina Ravazi de , Lima Vanessa Silvestre
Published: November 2022

O objetivo deste texto é analisar o painel do Crucifixo de Padova pintado por Giotto di Bondone (1266-1337) com direcionamento da premissa de que a imagem expressa a dualidade da natureza de Cristo por meio do corpo humano de Jesus.  O corpo humanizado de Cristo é compreendido, no estudo, como indício da mudança de mentalidade acerca dos conceitos de homem e de mundo que se consolidariam no Renascimento Italiano. A orientação metodológica se estabelece por meio dos preceitos apresentados por Matine Joly no que se refere as mensagens provenientes dos signos plásticos, icônicos e linguísticos. A análise dos três grupos de signos nos mostrou que Giotto expõe a natureza humana de Cristo evidenciando o corpo sofredor que possibilita, pela semelhança, a identificação do apreciador com o Mestre. Dessa forma, a pedagogia imagética se efetiva no Crucifixo de Giotto e nos possibilita verificar que as imagens, por meio de diferentes conotações, participam dos processos de formação humana em todos os tempos atendendo as demandas sociais ou instigando reflexões, propondo e anunciando mudanças.
Possibilidades formativas em educação física na perspectiva inclusiva
Authors: Nunes Jacqueline da Silva , Oliveira Patricia Santos de , Freitas Josiane Fujisawa Filus de , Rossi-Andrion Patricia
Published: November 2022

O presente trabalho é resultado dos desdobramentos do curso de extensão Corpo, Formação Humana e Sociedade, e teve como objetivo refletir sobre a formação inicial do professor de Educação Física para atuar junto às pessoas com deficiência. Assim, a partir de um ensaio teórico, as autoras iniciam refletindo sobre a temática do corpo, formação humana e sociedade e sua intersecção com a formação inicial de professores de Educação Física a partir das quais são apresentadas conceituações, bases teóricas e pesquisas recentes em formação inicial da área. Para finalizar, são apresentadas possibilidades e estratégias para formar professores sensíveis à temática da inclusão. Tais sugestões resultam de trabalhos de conclusão de curso, relatos e das experiências didáticas das pesquisadoras e estão organizadas a partir dos eixos: experiências nos estágios supervisionados, extensão universitária e formação para atuar na perspectiva do trabalho colaborativo.