bluuebunny/crossref_metadata_2025 huggingface dataset:
Viral Etiological Factors Causing Acute Encephalitis Syndrome (AES) In Gaya Division, India
Authors: Topno Roshan Kamal , Pandey Krishna , Singh Banke Bihari , Dikhit Manas Ranjan , Kumar Ashish , Kumar Maneesh , Sahoo Ganesh Chandra , Rabidas Vidya Nand , Siddiqui Niyamat Ali , Paswan Wakil , Lal Arjun , Dinesh Diwakar Singh , Das Pradeep
Published: October 2019

Background: From Gaya and adjoining regions, the trend in patients admitted with acute neurological illness was investigated. Illnesses were identified as sudden outbreaks of Japanese virus encephalitis (JE), Herpes simplex virus encephalitis (HSV1&2), and other acute encephalitis syndrome (AES). Objective: In the current study, an investigation was carried out to assess potential infectious pathogens in patients aged 16 years or younger who were admitted to Anugrah Narayan Magadh Memorial Medical College Hospital, Gaya, with encephalitis-like symptoms. Methods: Cross-epidemiological, serological, and molecular biological studies were performed on samples collected from 71 patients below 16 years of age. Patients’ clinical histories, i.e. fever, socio-demographic characteristics, and other clinical data, were extracted from patient files. Results: The results showed confirmed AES cases, including 49.30% JE and 7.04% HSV positive patients. A higher casefatality rate of 40% in JE and 40% HSV cases below 7 years of age were observed during treatment would become an unavoidable concern. The epidemical sex ratio was observed to be higher in girls than in boys (1.26:1). Conclusion: The results suggested that JE virus was found to be a main causative risk factor responsible for disease transmission in the outbreak area.
Borderline Personality Disorder Features and Risk for Prescription Opioid Misuse in a Chronic Pain Sample: Roles for Identity Disturbances and Impulsivity
Authors: Reynolds Caleb J. , Vest Noel , Tragesser Sarah L.
Published: October 2019

Although borderline personality disorder (BPD) is associated with both chronic pain and substance abuse, little research examines how BPD features in chronic pain patients may constitute a risk factor for misuse of prescription opioids, and no prior research has examined which particular component(s) of BPD might put chronic pain patients at risk—an oversight that undermines prevention and treatment of such problematic opioid use. In a cross-sectional study of patients in treatment for chronic pain (N = 147), BPD features were associated with several measures of prescription opioid misuse, even controlling for pain severity and interference. Specifically, the identity disturbances and self-harmful impulsivity facets of BPD were most consistently associated with opioid misuse, and exploratory analyses suggested that these factors may be interactive in their effects. Together, these results suggest that BPD features—especially unstable identity and self-harmful impulsivity—play a unique role in problematic prescription opioid use in chronic pain settings.
Apoio matricial na gestão do trabalho da atenção primária à saúde: uma revisão integrativa
Authors: Soares Danielle De Jesus , Rivemales Maria da Conceição Costa
Published: October 2019

Objetivo: investigar a produção bibliográfica sobre o apoio matricial na atenção primária à saúde. Métodos: trata-se de uma revisão integrativa. A busca se deu em Biblioteca Virtual de Saúde, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Medical Literature Analysis and Retrieval System Online, Banco de Dados em Enfermagem, em abril a maio de 2018. A análise dos dados foi de conteúdo. Resultados: 13 artigos foram incluídos na revisão. A análise dos artigos evidenciou que o Apoio Matricial contribui para a organização do processo gerencial na Atenção Primária à Saúde e suas diferentes perspectivas e formas de apoio ofertadas; foi possível identificar também os fatores tidos como facilitadores e dificuldades para o trabalho. Considerações finais: destaca-se a importância de realizar estudos que investiguem as práticas do Apoio Matricial, seus benefícios e entraves, assim como a formação continuada dos profissionais atuantes visando à busca pela integralidade da atenção.
Percepção de professores sobre ações de grupos de (re)conhecimento emocional
Authors: Auda Jéssica Maria de , Braga Gimene Cardozo , Junior Sidnei Teixeira , Ferreira Micheli De Jesus
Published: October 2019

Objetivo: identificar a percepção dos professores a respeito das ações desenvolvidas durante os grupos de (re)conhecimento emocional realizado com estudantes de uma escola de ensino fundamental. Método: trata-se de um estudo qualitativo descritivo. A coleta de dados deu-se por meio de entrevistas semiestruturadas com quatro professores, em 2014. Utilizou-se a análise temática, que emergiu duas categorias: “A percepção dos professores sobre os grupos de reconhecimento emocional” e “Aprendizagem dos professores”. Resultados: o grupo de (re)conhecimento emocional proporcionou a mudança do comportamento das crianças dentro da sala de aula e auxiliou na sensibilização dos professores para trabalhar com a identificação das emoções das crianças. Conclusão: a sensibilização dos professores participantes, ampliou os conhecimentos destes, sobre como identificar e trabalhar as emoções e sentimentos apresentados pelas crianças e contribuiu para a promoção de saúde mental infantil.
BILDIRCIN NUGGET ÜRETİMİ VE DEPOLAMA STABİLİTESİNİN BELİRLENMESİ
Authors: AKOĞLU Aylin , GÜLÜM Levent , AKOĞLU İlker Turan
Published: October 2019

Bu çalışmada bıldırcın nugget üretimi ve depolama
stabilitesinin belirlenmesi amaçlanmıştır. Çalışmada %75 bıldırcın eti ve %25
piliç eti kullanılarak nuggetlar (BN) üretilmiş, ardından 4°C ve -18°C’de
depolanarak kimyasal, mikrobiyolojik ve duyusal analizleri
gerçekleştirilmiştir. Yapılan analizlerde BN örneklerinin su, yağ, protein ve kül
içeriği sırasıyla, %55.97, %8.84, %16.17 ve %2.08 olarak tespit edilmiştir. Yağ
asitleri bileşimine bakıldığında, en yüksek orana sahip yağ asitleri linoleik
asit (%21.55), linolenik asit (%21.78) ve palmitik asit (%19.18) olarak
belirlenmiştir. Soğuk depolamada kimyasal analizlerden pH, peroksit, sertlik-2,
sakızımsılık, sıkılık; duyusal analiz parametrelerinde ise dış renk ve koku
değerlerindeki değişiklikler istatistik açıdan önemli bulunmuştur (P <0.05).
Donmuş depolamada ise su aktivitesi, peroksit, sertlik-2, sakızımsılık,
elastikiyet, çiğnenebilirlik, esneklik, sertlik-1 ve sıkılık değerlerindeki
değişimlerin istatistik olarak önemli olduğu tespit edilmiştir (P <0.05).
4°C’deki 20 günlük depolama sonunda TMAB, TPAB ve toplam Enterobacteriaceae
sayıları sırasıyla 5.70±0.3, 6.40±0.1 ve <1 log kob/g olarak bulunmuş, Salmonella
spp. ve Listeria monocytogenes ise tespit edilmemiştir.
Plume detection modeling of a drone-based natural gas leak detection system
Authors: Barchyn Thomas E. , Hugenholtz Chris H. , Fox Thomas A.
Published: October 2019

Interest has grown in using new screening technologies such as drones to search for methane leaks in hydrocarbon production infrastructure. Screening technologies may be less expensive and faster than traditional methods. However, including new technologies in emissions monitoring programs requires an accurate understanding of what leaks a system will detect and the resultant emissions mitigation. Here we examine source detection of a drone-based system with controlled releases. We examine different detection algorithm parameters to understand trade-offs between false positive rate and detection probability. Leak detection was poor under all conditions with an average detection probability of 0.21. Detection probability was not affected by emission rate, suggesting similar systems may commonly miss large leaks. Detection was best in moderate wind speeds and at 750–2000 m downwind from the source where the plume had diffused vertically above the minimum flight level of 40–50 m. Predicted concentration enhancement from a Gaussian plume model was a reasonable predictor of detection within the test suite. Enabling lower flight elevations may increase detection probability. Overall, the experiments suggest that controlled releases are useful and necessary to provide an understanding of detection probability of screening technologies for regulatory and deployment purposes, and the testing must be representative to support broad application.
The Influence of Liraglutide for Heart Failure: A Meta-Analysis of Randomized Controlled Trials
Authors: Zhang Yu , Chen Qingmei , Huang Guangyin , Wang Lisha
Published: October 2019

Introduction: The efficacy of liraglutide to treat heart failure remains controversial. We conducted a systematic review and meta-analysis to explore the influence of liraglutide on heart failure.
Methods: We searched PubMed, EMbase, Web of Science, EBSCO, and Cochrane library databases through March 2018 for randomized controlled trials (RCTs) assessing the effect of liraglutide on cardiac function of heart failure. Meta-analysis is performed using the random-effect model.
Results: Four RCTs involving 629 patients are included in the meta-analysis. Overall, compared with the control group for heart failure, liraglutide treatment significantly can reduce NT-proBNP (Std. MD = -3.06; 95% CI = -5.78 to -0.34; P = .03), and improve 6MWT (Std. MD=1.10; 95% CI = 0.75 to 1.44; P < .00001), but has no remarkable influence on LVEF change (Std. MD=1.10; 95% CI = -1.97 to 3.98; P = 0.51), LVEDV change (Std. MD = 6.26; 95% CI = -1.45 to 13.97; P = .11), LVESV change (Std. MD = -13.47; 95% CI = -31.04 to 4.10; P = .13), hospitalization for heart failure (RR = 1.18; 95% CI = 0.88 to 1.58; P = .27), major adverse cardiovascular events (RR = 1.55; 95% CI = -0.24 to 9.89; P = .64), and cardiac death (RR = 1.11; 95% CI = 0.61 to 2.04; P = .72).
Conclusions: Liraglutide treatment has an important ability to reduce NT-proBNP and improve 6MWT for heart failure, but shows no important influence on LVEF, LVEDV, LVESV, hospitalization for heart failure, major adverse cardiovascular events, and cardiac death.
A Parallel Computation Algorithm for Image Feature Extraction
Authors: A. Belousov  , J. Ratsaby
Published: October 2019

We present a new method for image feature-extraction for learning image classification. An image is represented by a feature vector of distances that measure the dissimilarity between regions of the image and a set of fixed image prototypes. The method uses a text-based representation of images where the texture of an image corresponds to patterns of symbols in the text string. The distance between two images is based on the LZ-complexity of their corresponding strings. Given a set of input images, the algorithm produces cases that can be used by any supervised or unsupervised learning algorithm to learn image classification or clustering. A main advantage in this approach is the lack of need for any image processing or image analysis. A non-expert user can define the image-features by selecting a few small images that serve as prototypes for each class category. The algorithm is designed to run on a parallel processing platform. Results on the classification accuracy and processing speed are reported for several image classification problems including aerial imaging.
Energy efficiency research of fermentation medium agitation in manufacturing of microbiological plant protection products
Authors: Yaroshevsky V.
Published: October 2019

Aim. The main aim of the research was to compare different methods of fermentation medium energy effi ciency agitation. Methods. The analysis of mass transfer processes in fermenters using different methods of agitation was made. Experimental determination of energy consumption for medium agitation while using a mechanical agitator and an external circulation loop was realized. Estimation of energy effi ciency indices. Results. It was determined that energy effi ciency of agitation by circulation during the cycle of bacterial preparation Planriz BT (Biotechnica) exceeded mechanical agitation 1.3 times in case of aeration, and 2.6 times in the non-aeration mode. Conclusions. The method of agitation by circulation of fermentation medium using an external loop is more energy-effi cient compared to mechanical agitation even in the case of using a slow-speed agitator.
IMPACT OF BREAK IN COLD CHAIN ON THE TECHNOLOGICAL AND ORGANOLEPTIC QUALITIES OF ATLANTIC MACKEREL (SCOMBER SCOMBRUS) AND HORSE MACKEREL (TRACHURUS TRACHURUS) IN SOUTH BENIN
Authors: Hospice Mahussi Assogba Martinien , Folakè Arikè Salifou Chakirath , Tobada Pamphile , Karimou Aboudou Abdou , Bio Bakary AÃ¯ssatou , Dahouda Mahamadou , Chikou Antoine , Farougou SouaÃ¯bou , Youssao Abdou Karim Issaka
Published: October 2019

Horse mackerel and Atlantic mackerel are species often imported and sold in Benin in frozen form. This study aimed to evaluate the impact of the break in cold chain on the technological and organoleptic qualities of these fish in south Benin. Thus, it was carried out from June to December 2016 in the Department of Atlantic and Littoral. For the study, fish samples (120 Atlantic mackerel and 120 Horse mackerel) were taken for laboratory analyzes. It appears that the weight of the whole fish, the weight of the eviscerated fish and the weight of the remains were significantly higher for the breaks of 6 hours than for the breaks of 3 hours and 12 hours. The fillet weight of fish at 6 hours (140.4g) of cold break was significantly higher than that at 3 hours (112g) of cold break. No influence of break in cold chain was observed on the yield, fillet yield, water content and pH. Whatever the break duration, the different weights recorded were significantly higher in Horse mackerel than in Atlantic mackerel. The various weights recorded in Atlantic mackerel with 3 and 12 hours of break were higher than those recorded with 6 hours of break. The red index was higher for the 6 hours of break than for the 12 hours of break (P
LITERASI KEUANGAN DALAM PERSPEKTIF MAHASISWA: (STUDI KASUS MAHASISWA FEBI IAIN LHOKSEUMAWE)
Authors: ISMAULINA ISMAULINA , SURYANI SURYANI
Published: October 2019

Every individual wants a happy and prosperous life. To achieve that it takes knowledge of financial literacy in order for someone to avoid financial problems. This study aims to examine how the level of financial literacy students majoring in Islamic economics Faculty of Economics and Business Islam (FEBI) IAIN Lhokseumawe. And whether the level of income affects the management and financial decisions of students of the Department of Sharia Economics FEBI IAIN Lhokseumawe. Respondents studied are students who come from FEBI majoring in Sharia Economics amounted to 100 people. Mean and frequency test were used in this study. The result of the study shows that the average score of financial literacy students of Economics Department of FEBI IAIN Lhokseumawe of 3.27 (65.4%) means that the level of student financial literacy is still far from the optimum or still quite enough, even close to the low category so it should be increased especially related to the knowledge of expenditure, credit, savings and investment. The average student income level lies in the medium/moderate category of 56%. Giving meaning differences in student income levels affect financial management and make the right financial decisions.
FORECASTING SAHAM SYARIAH DENGAN MENGGUNAKAN LSTM
Authors: FAUZI AHMAD
Published: October 2019

Islamic stocks as one of the many stocks listed on the JCI are a barometer of the Islamic market in Indonesia. One approach in predicting stock prices is by using machine learning. The purpose of this study is to make a model that is used to predict JII shares using the LSTM approach. The data used amounted to 1402 records related to the Jakarta Islamic Index (JII) stock from March 4, 2014 - January 2, 2019. Model making uses 3 Epochs (1, 10 and 20). The results showed the best model was to use 20 Epochs. The increase in Epoch affects the value of MSE and RMSE which are getting smaller. For Epoch 20, the values of MSE and RMSE are ~ 0.00019 and ~ 0.014, respectively.
Pre-Schwarzian norm for linear operators of uniformly convex functions of order α and type β
Authors: Dziok Jacek , Zayed Hanaa M.
Published: October 2019

By making use of the pre-Schwarzian norm given by
we obtain such norm estimates for Hohlov operator of functions belonging to the class of uniformly convex functions of order α and type β. We also employ an entirely new method to generalize and extend the results of Theorems 1, 2 and 3 in [3]. Finally, some inequalities concerning the norm of the pre-Schwarzian derivative for Dziok-Srivastava operator are also considered.
Good congruences on abundant semigroups with quasi-ideal adequate transversals
Authors: Wang Aifa
Published: October 2019

The aim of this paper is to study the congruences on abundant semigroups with quasi-ideal adequate transversals. The good congruences on an abundant semigroup with a quasi-ideal adequate transversal S° are described by the equivalence triple abstractly which consists of equivalences on the structure component parts I, S° and Λ. Also, it is shown that the set of all good congruences on this kind of semigroup forms a complete lattice.
Various notions of represetability for cylindric and polyadic algebras
Authors: Ahmed Tarek Sayed
Published: October 2019

For β an ordinal, let PEAβ (SetPEAβ) denote the class of polyadic equality (set) algebras of dimension β. We show that for any infinite ordinal α, if is atomic, then for any n < ω, the n-neat reduct of , in symbols , is a completely representable PEAn (regardless of the representability of ). That is to say, for all non-zero , there is a and a homomorphism such that fa(a) ≠ 0 and for any for which exists. We give new proofs that various classes consisting solely of completely representable algebras of relations are not elementary; we further show that the class of completely representable relation algebras is not closed under ≡∞,ω. Various notions of representability (such as ‘satisfying the Lyndon conditions’, weak and strong) are lifted from the level of atom structures to that of atomic algebras and are further characterized via special neat embeddings. As a sample, we show that the class of atomic CAns satisfying the Lyndon conditions coincides with the class of atomic algebras in ElScNrnCAω, where El denotes ‘elementary closure’ and Sc is the operation of forming complete subalgebras.
A Catalogue of Harbours in the Province of Ĝirsu/Lagaš Documented in the Administrative Texts of the Ur III Period
Authors: Alivernini Sergio
Published: October 2019

As is well known, boat trips on rivers and canals were an essential part of Mesopotamian economy at the end of the 3rd millennium BC; the Tigris and Euphrates, with their tributaries and canals, served as major highways in Mesopotamia. In the Ur III period, inland traffic by waterway was very extensive (more so than interregional water transport). This paper aims at highlighting ports/harbours of the province of Ĝirsu/Lagaš recorded in the administrative texts from the end of the 3rd millennium, by cataloguing the name of the places where these harbours are located.
A New Analysis of Kalbak Taš I (A-23) Inscription
Authors: Yildiz Hülya
Published: October 2019

This paper focuses on Kalbak-Taš I inscription which belongs to the Mountainous Altai group. It provides an analysis of the problematic issues of the inscription that have emerged in previous studies, as well as some new reading proposals for some parts of the inscription. The transliterations of Kalbak-Taš I given by the previous researchers differ from one another regarding some sign decipherments. Our study evaluates those decipherments and eliminates the problematic identifications. It reveals the most acceptable transliteration of the inscription through a detailed analysis of the photograph of Kalbak-Taš I inscription taken and published by Tybykova et al. (2012). The author considers the sign groups , , , , <ẄrmAT>, ,  as separate lexical units. The inscription is transcribed and translated here as yer bäŋgü ärmiš atam bädzägi äšgin bessiŋä ürmät1[i] ičdä yryä (…) ‘The earth has been eternal. (This is) my father's ornament (inscription?). Without blowing to his ambling mare, from the court northwards (…)’.
Applying Internalised Source-culture Knowledge to Solve Cultural Translation Problems. A Quasi-experimental Study on the Translator's Acquisition of Cultural Competence
Authors: Olalla-Soler Christian
Published: October 2019

In this article, the ability to efficiently apply internalised source-culture knowledge when solving cultural translation problems is analysed at different stages of acquisition of the translator's cultural competence by means of a cross-sectional, quasi-experimental study. Thirty-eight BA students from the first through fourth year studying Translation and Interpreting at the Universitat Autònoma de Barcelona, as well as ten professional translators participated in this investigation. The subjects’ knowledge of German culture and their knowledge of a selection of cultural translation problems in a text were measured prior to its translation. The translation strategies employed by the subjects to solve these problems were recorded and classified using PACTE's (2017b) sequences of actions. The quality of the subjects' solutions to the cultural translation problems of the text was assessed with PACTE's (2017a) acceptability index. These data were combined to compute the source-culture knowledge application index. Results show that the students in all cohorts preferred to utilise information-seeking strategies even when they possessed cultural knowledge about a specific cultural translation problem, while the professional translators in this study were able to apply their internalised source-culture knowledge. The solutions proposed by both the translation students and the professional translators were of a higher quality when internalised source-culture knowledge was applied.
Augmentation of Vortex Cavitator Performance by the Use of Co-Directional Swirl of the Flux after Vortex Chamber
Authors: Ivanov Evgeniy Gennadievich , Gorbunov Boris Ivanovich , Pasin Alexander Valentinovich , Aryutov Boris Alexandrovich , Novozhilov Alexei Ivanovich
Published: October 2019

Background: Acoustic cavitation is the creation and collapse of cavitation caverns in liquid in an acoustic field with a frequency of f = 1–3 kHz. The acoustic-cavitation processes manifest themselves during the collapse phase, with high pressure gradient continuum deformation, with a multiple transformation of energy forms. Liquid whistles are widely used to create an acoustic field of high power, but their efficiency only reaches 6–12%. We propose a liquid whistle in the form of a vortex cavitator (analogue of the Ranque vortex tube) with a rotating body in which a reduction in the input power is predicted.

Objective: Verification of feasibility of using a rotating body in a vortex cavitator with a rotation co-directional to the operational pump impeller.

Method: The method for identifying the feasibility of using a rotating body is to exclude body from the prototype and directly connect vortex chamber outlet with the pump inlet, which ensures the most complete preservation of co-directional vortex component of the flux entering the pump impeller.

Results: The results of experimental studies confirmed the validity of the hypothesis to a greater extent, since we achieved an increase in pressure at the outlet of the pump and a decrease in power at the drive relative to the original design.

Conclusions: The feasibility of designing the vortex cavitator body with rotation capability has been established, which will provide a reduction in input power of at least 30% by a rotation of the body, co-directional with the impeller.
New records and range expansion of Chironius carinatus (Linnaeus, 1758) (Serpentes, Colubridae) from the state of Paraíba, northeast Brazil
Authors: Araújo Paula , França Rafaela Candido de , Nascimento Fernanda Soares do , Laranjeiras Daniel Orsi , França Frederico Gustavo Rodrigues
Published: October 2019

The current work provides a new state record of the snake Chironius carinatus (Linnaeus, 1758) based on two specimens collected in the Atlantic Forest of Paraíba state, northeastern Brazil. This species occurs in the Amazon and Atlantic Forests. The new records fills in a gap in the species’ distribution on the Brazilian coast. In Paraíba, C. carinatus occurs in sympatry with two other Chironius Fitzinger, 1826 species, C. flavolineatus Jan, 1863 and C. exoletus (Linnaeus, 1758).
Farklı kurutma yöntemlerinin 12-Kadıoğlu kayısı çeşidinin uçucu organik bileşenleri üzerine etkisi
Authors: KAPLAN Mustafa , LEVENT Okan
Published: October 2019

Malatya kayısısı tıbbi ve aromatik yönüyle
önemli bir meyvedir. 12-Kadıoğlu kayısı çeşidinin orijini Malatya olup,
sofralık ve kurutmalık olarak değerlendirilmektedir. Beslenme fizyolojisi
açısından önem arzeden kayısı, temel beslenme öğelerini içermesinin ötesinde
insan fizyolojisi ve metabolik fonksiyonları üzerinde sağlık ve hastalıkların
oluşmasını önlemede ilave faydalar sağlamaktadır. İnsan beslenmesinde kayısı
gibi antioksidan kapasitesi yüksek gıdaların kullanılması özendirilmektedir. Malatya
dünya taze kayısı üretiminde %12 ve kuru kayısı üretiminde ise yaklaşık %65’lik
bir paya sahiptir. Bu çalışmada, farklı kurutma yöntemlerinin (güneşte kurutma,
kükürtleme işleminden sonra güneşte kurutma ve fırın kurutucuda kurutma)
12-Kadıoğlu kayısı çeşidinin uçucu organik bileşik profili üzerine etkisi
incelenmiştir. Kurutma ve kükürtleme işlemi uçucu organik bileşikler üzerinde
önemli derecede etkili olmuştur. Kükürt uygulaması ve miktarına bağlı olarak
uçucu organik bileşiklerin miktarının azaldığı belirlenmiştir. Uçucu organik
bileşik miktarlarındaki değişim üzerinde farklı kurutma yöntemlerinin
istatistiksel olarak (p<0.05) önemli etkisi olduğu tespit edilmiştir.
Informative Indicators of Functional and Motor Fitness of Students of Higher Education Institutions
Authors: Chernenko S. , Honcharenko O. , Marchenko S.
Published: October 2019

The study objective was to determine informative indicators of functional and motor fitness of 1st-5th year students.
Materials and methods. The study involved male students of 1st year (n = 67), 2nd year (n = 66), 3rd year (n = 62), 4th year (n = 45), 5th year (n = 56). The following research methods were used to solve the tasks set: analysis of scientific literature, pedagogical observation, pedagogical testing; index method and medical-biological methods. Pedagogical methods were used to study the peculiarities of functional state of the body and motor abilities of 1st-5th year students of higher education institutions; factor analysis was used for data processing.
Results. By the Ruffier index, the 1st-2nd year students have an average heart performance. The 3rd-5th year students have a satisfactory heart performance. By the results of the Stange and Genci tests, the 1st-5th year students are evaluated as healthy and fit. According to the Romberg test, the 1st and 5th year students show higher results than the 2nd, 3rd and 4th year students (p < 0.001; p < 0.001; p < 0.006, respectively). The 3rd year students have the lowest results. The test results are estimated as lower than normal.
Conclusions. The analysis of motor and functional fitness of the 1st-5th year students showed that the first factor in their structure is the functional state of the respiratory system, the second factor is speed strength and strength fitness. The most informative tests are: 1st year – the Stange test (0.822) and Genci test (0.741); 2nd year – the Genci test (0.758), the Rufier index has the lowest informativity (0.11); 3rd year – “Standing long jump” (0.741) and the Genci test (0.723); 4th year – the Stange test (0.927) and Genci test (0.810); 5th year – the Stange test (0.799).
Description of Motor and Functional Fitness of 4th-5th Grade Boys of a Rural Underfilled School
Authors: Tolstoi A. O.
Published: October 2019

The study purpose was to determine the dynamics of motor and functional fitness of 4th-5th grade boys of a rural underfilled school during the school year.

Materials and methods. The study participants were boys of 4th grade (n = 9) and 5th grade (n = 5). During parent-teacher meetings, the children and their parents were informed about all the features of the study and gave their consent to participate in the experiment. The study used the following research methods: analysis of scientific and methodological literature, pedagogical testing, and methods of mathematical statistics for processing research results.

Results. On average, the 4th grade boys’ results are 10.8 times better in push-ups (p < 0.05); 5.3 times better in pull-ups (p < 0.05); 15.3 s better in bent-arm hang (p < 0.05). By the results of other motor tests, the differences between average values are statistically non-significant (p > 0.05).

Conclusions. The general level of the pupils’ functional and motor fitness is sufficient. There are statistically significant differences between the 4th and 5th grade boys in push-ups, pull-ups, bent-arm hang, Stange test, Serkin test (p < 0.05). By the results of other tests, the differences between average values are statistically non-significant (p > 0.05).
Motor Skills Development: Optimization of Teaching Boys Aged 14
Authors: Kapkan O. , Khudolii O. M. , Bartik P.
Published: October 2019

The study objective is to substantiate the modes of alternation of physical exercises and rest intervals in the process of teaching series of tasks aimed at motor skills development in boys aged 14 years. 
Materials and methods. The participants in the study were 40 boys aged 14. The children and their parents were fully informed about all the features of the study and gave their consent to participate in the experiment. To achieve the objective set, the following research methods were used: study and analysis of scientific and methodological literature; pedagogical observation, timing of training tasks; pedagogical experiment, methods of mathematical statistics, methods of mathematical experiment planning.
Results. The results of the analysis of variance and regression models show that the optimal mode of performing series of training tasks is within the range of 6-12 exercise repetitions with rest intervals of 60-120 seconds. In the proposed matrix of factorial design, the selected step of factor variation is sufficient to study the impact of different modes of physical exercises on the effectiveness of teaching children and adolescents. 
Conclusions. A 22 type experiment made it possible to examine the multifactorial structure of the process of teaching boys aged 14, using the program of algorithmic instructions, to specify the optimal balance between factors for their use when teaching physical exercises during physical education classes.
The best options for teaching series of tasks to boys aged 14 during physical education classes are: series 1 — 12 repetitions, rest interval of 120 s; series 2 — 12 repetitions, rest interval of 60 s; series 3 — 6 repetitions, rest interval of 60 s; series 4 — 12 repetitions, rest interval of 60 s; series 5 — 12 repetitions, rest interval of 120 s; series 6 — 6 repetitions, rest interval of 60 s.
Sanger sequencing v1
Authors: Dusseldorf Igem
Published: October 2019

1. Label 1.5 mL tubes with barcodes from GATC Biotech (stored on top shelf in our office) 2. Add template (400 to 500 ng), primer and water (10 uL total volume, details below) uL per Reaction BarcodeTemplatePrimerTemplate#ERROR! 10 uM Primer2.5 Water#ERROR! Total Volume10.0 3. Place tubes inside a small plastic bag and drop off in GATC Collection Box by 5:30 pm. 4. Results are usually ready to download from the gatc-biotech.com or Dropbox (details below) the next business day after 12 pm. The GATC collection point is located at the exit of building 26.43,opposite to building 26.53. Daily pick up of your samples from Monday to Friday 5:30 pm.
Formation of gp37 LTF needle trimers-LPS complex v1
Authors: Z. Islam Mohammad , Fokine Andrei , Mahalingam Marthandan , Zhang Zhihong , Garcia-Doval Carmela , J. van Raaij Mark , G. Rossmann Michael , Venigalla B. Rao and
Published: October 2019

Tailed bacteriophages (phages) are one of the most abundant life forms on Earth. They encode highly efficient molecular machines to infect bacteria, but the initial interactions between a phage and a bacterium that then lead to irreversible virus attachment and infection are poorly understood. This information is critically needed to engineer machines with novel host specificities in order to combat antibiotic resistance, a major threat to global health today. The tailed phage T4 encodes a specialized device for this purpose, the long tail fiber (LTF), which allows the virus to move on the bacterial surface and find a suitable site for infection. Consequently, the infection efficiency of phage T4 is one of the highest, reaching the theoretical value of 1. Although the atomic structure of the tip of the LTF has been determined, its functional architecture and how interactions with two structurally very different Escherichia coli receptor molecules, lipopolysaccharide (LPS) and outer membrane protein C (OmpC), contribute to virus movement remained unknown. Here, by developing direct receptor binding assays, extensive mutational and biochemical analyses, and structural modeling, we discovered that the ball-shaped tip of the LTF, a trimer of gene product 37, consists of three sets of symmetrically alternating binding sites for LPS and/or OmpC. Our studies implicate reversible and dynamic interactions between these sites and the receptors. We speculate that the LTF might function as a “molecular pivot” allowing the virus to “walk” on the bacterium by adjusting the angle or position of interaction of the six LTFs attached to the six-fold symmetric baseplate.
Binding of gp37 LTF needle trimers to E. coli v1
Authors: Z. Islam Mohammad , Fokine Andrei , Mahalingam Marthandan , Zhang Zhihong , Garcia-Doval Carmela , J. van Raaij Mark , G. Rossmann Michael , Venigalla B. Rao and
Published: October 2019

Tailed bacteriophages (phages) are one of the most abundant life forms on Earth. They encode highly efficient molecular machines to infect bacteria, but the initial interactions between a phage and a bacterium that then lead to irreversible virus attachment and infection are poorly understood. This information is critically needed to engineer machines with novel host specificities in order to combat antibiotic resistance, a major threat to global health today. The tailed phage T4 encodes a specialized device for this purpose, the long tail fiber (LTF), which allows the virus to move on the bacterial surface and find a suitable site for infection. Consequently, the infection efficiency of phage T4 is one of the highest, reaching the theoretical value of 1. Although the atomic structure of the tip of the LTF has been determined, its functional architecture and how interactions with two structurally very different Escherichia coli receptor molecules, lipopolysaccharide (LPS) and outer membrane protein C (OmpC), contribute to virus movement remained unknown. Here, by developing direct receptor binding assays, extensive mutational and biochemical analyses, and structural modeling, we discovered that the ball-shaped tip of the LTF, a trimer of gene product 37, consists of three sets of symmetrically alternating binding sites for LPS and/or OmpC. Our studies implicate reversible and dynamic interactions between these sites and the receptors. We speculate that the LTF might function as a “molecular pivot” allowing the virus to “walk” on the bacterium by adjusting the angle or position of interaction of the six LTFs attached to the six-fold symmetric baseplate.
Farmakovijilans: Türk Mevzuatı Açısından Bir Değerlendirme
Authors: ERGÜN Yusuf
Published: October 2019

Advers ilaç reaksiyonları hem
hastaları hem de sağlık profesyonellerini zorlayan temel sağlık problemlerinden
biridir. Bundan dolayı, bu reaksiyonlar iyi kurulmuş bir farmakovijilans
sistemi aracılığıyla izlenmelidir. Sağlık profesyonelleri hasta ve toplum
güvenliğinin sağlanması için bu sistemden haberdar olmalı ve eğitilmelidir. Bu
derlemede, sağlık profesyonellerinin daha fazla aksiyon almasını stimüle etmek
amacıyla farmakovijilans sistemi ulusal mevzuat açısından tartışılmaktadır.
A Four Marker Digital PCR Toolkit for Detecting Heavy Alcohol Consumption and the Effectiveness of Its Treatment
Authors: Philibert Robert , Miller Shelly , Noel Amanda , Dawes Kelsey , Papworth Emma , Black Donald W , Beach Steven R. H , Long Jeffrey D , Mills James A , Dogan Meeshanthini
Published: October 2019

Background.—Heavy alcohol consumption (HAC) is a shared concern of the forensic, medical and insurance underwriting communities. Unfortunately, there is a relative lack of clinically employable tools for detecting HAC and monitoring treatment response. Building on the results of 3 genome wide methylation studies, we have previously shown in a small group of samples that methylation sensitive digital PCR assays (MSdPCR) have the potential to accurately classify individuals with respect to HAC in a small set of individuals.

Objective.—We now expand on those earlier findings using data and biomaterials from 143 participants with current HAC and 200 abstinent controls.

Results.—We show that a set of 4 digital PCR assays that have a receiver operating characteristic (ROC) area under the curve (AUC) of 0.96 for detecting those with HAC. After a mean of 21 days of inpatient enforced abstinence, methylation status at one of these markers, cg04987734, began to revert to baseline values. Re-examination of methylation data from our smaller 2014 study with respect to this locus demonstrated a similarly significant reversion pattern at cg04987734 in association with treatment enforced abstinence.

Conclusions.—We conclude that clinically implementable dPCR tools can sensitively detect the presence of HAC and that they show promise for monitoring alcohol treatment results. These dPCR tools could be useful to clinicians and researchers in monitoring those enrolled in substance use disorder treatment, employee wellness programs and insurance underwriting.
Medical Malpractice Defense: The Predictive and Protective Power of Mortality, Survival, and Life Expectancy
Authors: Milano Anthony F , Beck Gill P
Published: October 2019

Introduction.—The defense of medical malpractice presents a significant challenge to Assistant United States Attorneys (AUSAs). A medical malpractice claim consists of proof of: (1) duty, (2) breach of the duty, (3) causation, and (4) damages. Often the breach of the duty and the causation elements present complex medical issues involving multiple specialties and subspecialties of medicine. A considerable amount of time is required to prepare the defense pertaining to the alleged breach of the duty and causation elements. The damages aspect of the medical malpractice case is often not given equal treatment and may not be fully developed. As a result, damage awards can be surprisingly high once the breach of the standard of care and the causation defenses fail.

Purpose.—The purpose of this article is to underscore the importance of developing the damages aspect of the case. This article will demonstrate through a case study the power of using fact-based medical-actuarial risk statistics and life expectancy testimony to limit, by thousands if not millions of dollars, economic damages to impairment-specific “years of life lost” in medical-malpractice torts. The important points to remember are that from the moment a case is assigned to an AUSA, the AUSA must: (1) focus as much, if not more, attention on damages; (2) execute a discovery strategy that ensures all aspects of damages are thoroughly investigated; and (3) retain the appropriate experts, including, in appropriate cases, an expert on medical risk appraisal and life expectancy.
O zurro do burro: apontamentos sobre Λούκιος ἤ Ὄνος
Authors: Cardoso Igor B.
Published: October 2019

A transformação mágica de humanos em animais é tema recorrente na literatura antiga. O artigo propõe investigar a singularidade dessa metamorfose em Lúcio ou o asno – narrativa ficcional em prosa –, a partir da compreensão de elementos políticos específicos ao século II, a saber, a valorização da tradição e cultura helênicas sob o patrocínio dos imperadores antoninos. Para tanto, o ideal platônico de filósofo rei será cotejado com o conceito de cidade interior proposto por Marco Aurélio. A conclusão é de que a ficcionalidade da narrativa em prosa, invenção própria do período pesquisado, foi capaz de expressar um comportamento político que evidencia os silêncios e o não dito oriundos de uma nova consciência do tempo histórico.
Propércio e as artes visuais
Authors: Martins Paulo , Rodrigues Mariana Marchini
Published: October 2019

Nas elegias de Propércio é possível notar uma alusão recorrente ao universo das artes visuais que se manifesta de forma diversa, ora através da descrição de monumentos artísticos, como na elegia 2.31, ora através da citação de pintores, como na elegia 3.9, ou, ainda, a partir das inúmeras descrições dos personagens, Cíntia e Propércio, que mostraram possuir forte influência temática de pinturas e esculturas na sua composição, como na 1.3. Valendo-se de tal alusão, o presente artigo visa a compreender qual seria o conceito de arte visual que estaria presente nas elegias de Propércio, a partir da seleção e análise das elegias em que este tema estava em mais larga medida presente. Ainda, conforme mostraremos, as referências articuladas pelo elegíaco, para além de auxiliarem na compreensão quanto à concepção de Propércio acerca das artes visuais, o que confere mais uma perspectiva do conceito de arte circulante na Antiguidade Clássica, exercem uma função primordialmente metapoética, de modo que Propércio acaba por revelar também a concepção artística acerca de sua própria poesia.
The Making of Merovingian Paris: The Christianization of a Gallo-Roman city
Authors: Pessoa Tomás
Published: October 2019

The present paper intends to analyze the Christianization of the city of Paris and its growing importance in the Merovingian period. The article begins with an introduction of the context of the Gallo-Roman city and the transformations that happened during the final centuries of the Roman Empire. In the third section, the Merovingian Paris will be examined (6th-7th centuries), specifically its three most important churches. Finally, in the final section of the paper, the process on which Paris, a relatively unimportant city at a regional level until the sixth century, became one of the most important cities in Merovingian Gaul will be explained. The consolidation of the Merovingian royal power and the Christianization of the city were part of the same process.
Ways to Counteract the Negative Effects of Overtourism at Tourist Attractions and Destinations
Authors: Kruczek Zygmunt
Published: October 2019

Nadmierna koncentracja ruchu turystycznego (overtourism) prowadzi do zatłoczenia atrakcyjnych miejsc oraz przereklamowania i agresywnej komercjalizacji, co obniża poziom estetycznych doznań turystów i skutkuje degradacją naturalnych i kulturowych zasobów. Efektem nadmiernej frekwencji turystów jest wzrost cen usług, mieszkań i nieruchomości. W miastach historycznych dochodzi przez to do gentryfikacji zabytkowych dzielnic. Celem pracy było ukazanie genezy zjawiska zwanego overtourismem, jego rozwoju oraz działań mających na celu ograniczenie jego negatywnych skutków. Artykuł został oparty na przeglądzie literatury oraz na obserwacji zjawisk towarzyszących nadmiernej frekwencji turystów w 2018 r., opisywanych w mediach społecznościowych i identy fi kowanych na terenie zabytkowej dzielnicy Krakowa. Omówiono negatywne skutki overtourismu obserwowane w atrakcjach i destynacjach turystycznych, ilustrując ten problem przykładami ze świata i z Polski. Proces gentryfikacji pokazano, posługując się przykładem Krakowa. Ponadto zestawiono opisane w literaturze i doniesieniach medialnych działania na rzecz łagodzenia negatywnych skutków overtourismu. Dotyczą one zarówno działań po stronie podaży ofert usług turystycznych jak i popytu na te usługi. Wskazano na potrzebę budowania kompromisu pomiędzy trzema stronami interesariuszy: mieszkańcami, turystami i branżą turystyczną.
Świat człowieka i jego granice w świetle danych językowych
Authors: M. Tołstojowa Swietłana
Published: October 2019

Autorka przedstawia w syntetycznej formie najważniejsze problemy związane z językowym „uczłowieczaniem rzeczywistości”. Różne aspekty i różne formy antropocentryzmu analizuje na podstawie danych językowych, tekstów folkloru, podań wierzeniowych i rytualnych praktyk. Ujmuje antropocentryzm zarówno od wewnątrz, jak też od zewnątrz, tzn. nie tylko od człowieka do świata, ale i od świata do człowieka. Bowiem człowiek nie tylko „przyswaja” sobie świat, nakłada na niego swoje piętno, ale też „przymierza” samego siebie do świata zwierząt, roślin, czy rzeczy materialnych. Kolejno omawiane są więc dwa aspekty wzajemnych relacji człowiek a zwierzę, roślina, przyroda, świat materii z pokazaniem językowych i kulturowych wykładników uczłowieczania zwierząt, roślin, przyrody i rzeczy w kontraście do upodobniania człowieka do zwierząt, roślin, przyrody, przedmiotów; oraz dwa aspekty relacji człowiek a świat demoniczny i boski z pokazaniem językowych i kulturowych wykładników uczłowieczania demonów, Boga i świętych w kontraście do demonologizacji i ubóstwiania człowieka.

W zakończeniu, nawiązując do kontrastowych opinii Wiaczesława Iwanowa (który akceptuje antropiczną zasadę układu świata i ideę antropocentryzmu w jego aspekcie teleologicznym) i Miriany Detelić (która maksymę «człowiek jest miarą wszystkich rzeczy» uznaje za szkodliwą, bo usprawiedliwia niszczenie biosfery w skali kosmicznej), autorka artykułu podkreśla, że problemy miejsca człowieka w świecie i granic, oddzielających człowieka od innych mieszkańców Wszechświata, są aktualne także dla naszego czasu.
(White) lies and (pieux) mensonges: ethnolinguistic elaborations on not telling the truth
Authors: Peeters Bert
Published: October 2019

Fakt, iż w większości języków europejskich istnieją słowa podobne do angielskiego lie ‘kłamać’ sugeruje, że jest to uniwersalna kategoria poznawcza. Może się zatem wydawać, że wszyscy ludzie intuicyjnie rozumieją, czym jest lying ‘kłamstwo’ i że wszelkie formy dyskursu, w których ma miejsce mijanie się z prawdą, bez względu na ich pochodzenie, można uznać za formę lying. To jednak mit – różnice istnieją nawet w Europie, a w miarę, jak się od niej oddalamy, stają się coraz wyraźniejsze. Na przykład w opartym na angielszczyźnie melanezyjskim kreolskim języku bislama nie występuje ścisły odpowiednik angielskiego lie – najbliższym słowem jest czasownik giaman, który w przeciwieństwie do lie oznacza dosyć powszechnie akceptowany, czasami wręcz konieczny sposób postępowania. Z drugiej strony, przynajmniej z anglocentrycznego punktu widzenia, chociaż lying najczęściej odbierane jest jako moralnie naganne, istnieją przypadki, gdzie nie jest to oczywiste. Niektóre kłamstwa uznaje się za nie tak złe, jak inne – określa się je jako white lies ‘białe kłamstwa’ (istnieją także inne sformułowania, jednak to jest najczęstsze i najbardziej wyraziste kulturowo). Czy pojęcie to występuje w innych językach, np. we francuskim? W języku tym istnieje wyrażenie pieux mensonge, dosł. ‘pobożne kłamstwo’. W artykule staram się wykazać, iż semantyka wyrażeń white lies i pieux mensonges częściowo się pokrywa, lecz także, że mają one inne konotacje, które opisuję za pomocą Naturalnego Metajęzyka Semantycznego.