bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of self-report screening measures in the detection of depressive and anxiety disorders among children and adolescents with systemic lupus erythematosus
Authors: Quilter Michelle , Hiraki Linda , Knight Andrea M , Couture Julie , Levy Deborah , Silverman Earl D , Danguecan Ashley N , Ng Lawrence , Dominguez Daniela , Cost Katherine T , Neufeld Kate M , Schachter Reva , Korczak Daphne J
Published: June 2021

Background

There are no validated screening measures for depressive or anxiety disorders in childhood Systemic Lupus Erythematosus (cSLE). We investigated cross-sectionally (1) the prevalence of depressive and anxiety disorder in cSLE. (2) the validity of the Centre for Epidemiologic Studies Depression Scale for Children (CES-DC) and the Screen for Childhood Anxiety and Related Disorders (SCARED) measures in identifyingthese disorders.

Methods

Participants 8-18 years with cSLE/incipient cSLE completed CES-DC, SCARED, and Quality OfMy Life (QOML) measures. Parents completed the SCARED-Parent measure. Diagnosis was by gold-standard psychiatric interview and determined prevalence of psychiatric disorder. Receiver Operating Characteristics Area under the Curve (ROCAUC) evaluated screening measure diagnostic performance.

Results

Ofseventy-two parent-child dyads, 56 interviews were completed. Mean screen scores were: CES-DC = 15 (range 1-49, SD 12), SCARED-C = 22 (range 2-61, SD 14), SCARED-P = 13 (range 0-36, SD 8). Depressive disorder screen positivity (CES-DC ≥ 15) was 35% (vs. prevalence 5%). Anxiety disorder screen positivity (SCARED ≥ 25) was 39% (vs. prevalence 16%). CES-DC ROCAUC = 0.98 and SCARED-C ROCAUC = 0.7 (cut-points 38 and 32 respectively).

Conclusions

Diagnostic thresholds for depressive and anxiety disorderscreening measures are high for both CES-DC and SCARED-C in cSLE. Brief focused interview should follow to determine whether psychiatric evaluation is warranted.
l2-Penalized temporal logit-mixed models for the estimation of regional obesity prevalence over time
Authors: Burgard Jan P , Krause Joscha , Münnich Ralf , Morales Domingo
Published: June 2021

Obesity is considered to be one of the primary health risks in modern industrialized societies. Estimating the evolution of its prevalence over time is an essential element of public health reporting. This requires the application of suitable statistical methods on epidemiologic data with substantial local detail. Generalized linear-mixed models with medical treatment records as covariates mark a powerful combination for this purpose. However, the task is methodologically challenging. Disease frequencies are subject to both regional and temporal heterogeneity. Medical treatment records often show strong internal correlation due to diagnosis-related grouping. This frequently causes excessive variance in model parameter estimation due to rank-deficiency problems. Further, generalized linear-mixed models are often estimated via approximate inference methods as their likelihood functions do not have closed forms. These problems combined lead to unacceptable uncertainty in prevalence estimates over time. We propose an l2-penalized temporal logit-mixed model to solve these issues. We derive empirical best predictors and present a parametric bootstrap to estimate their mean-squared errors. A novel penalized maximum approximate likelihood algorithm for model parameter estimation is stated. With this new methodology, the regional obesity prevalence in Germany from 2009 to 2012 is estimated. We find that the national prevalence ranges between 15 and 16%, with significant regional clustering in eastern Germany.
Detection by real-time quaking-induced conversion (RT-QuIC), ELISA, and IHC of chronic wasting disease prion in lymph nodes from Pennsylvania white-tailed deer with specific PRNP genotypes
Authors: Tewari Deepanker , Steward David , Fasnacht Melinda , Livengood Julia
Published: June 2021

Chronic wasting disease (CWD) is a prion-mediated, transmissible disease of cervids, including deer ( Odocoileus spp.), which is characterized by spongiform encephalopathy and death of the prion-infected animals. Official surveillance in the United States using immunohistochemistry (IHC) and ELISA entails the laborious collection of lymphoid and/or brainstem tissue after death. New, highly sensitive prion detection methods, such as real-time quaking-induced conversion (RT-QuIC), have shown promise in detecting abnormal prions from both antemortem and postmortem specimens. We compared RT-QuIC with ELISA and IHC for CWD detection utilizing deer retropharyngeal lymph node (RLN) tissues in a diagnostic laboratory setting. The RLNs were collected postmortem from hunter-harvested animals. RT-QuIC showed 100% sensitivity and specificity for 50 deer RLN (35 positive by both IHC and ELISA, 15 negative) included in our study. All deer were also genotyped for PRNP polymorphism. Most deer were homozygous at codons 95, 96, 116, and 226 (QQ/GG/AA/QQ genotype, with frequency 0.86), which are the codons implicated in disease susceptibility. Heterozygosity was noticed in Pennsylvania deer, albeit at a very low frequency, for codons 95GS (0.06) and 96QH (0.08), but deer with these genotypes were still found to be CWD prion-infected.
Pediatric Hematology/Oncology Nurse Spirituality, Stress, Coping, Spiritual Well-being, and Intent to Leave: A Mixed-method Study
Authors: Murphy Jane M. , Chin Elizabeth D. , Westlake Cheryl A. , Asselin Marilyn , Brisbois Maryellen D.
Published: June 2021

Background: Intense emotional demands of oncology nursing create a stressful work environment and increase the likelihood of leaving. The study aims to explore, describe, and understand how pediatric hematology/oncology nurses caring for chronically ill or dying patients use their spirituality to cope with job stress, maintain spiritual well-being (SWB), and continue to work in this specialty. Methods: A concurrent mixed-method research design consisted of a web-based survey and interview. Data collection included demographics, intent to leave questions, and four valid and reliable research instruments measuring spirituality, stress, coping, and SWB. A responsive interview guide directed interviews. Results: Quantitative analysis ( n = 130) revealed moderate to high levels of spirituality, moderate stress, coping, and SWB. Stress and SWB were weakly, inversely correlated ( r = −.221, p = .011) indicating lower stress was associated with greater SWB. Coping and SWB were weakly, positively correlated ( r = .248, p = .005) indicating greater coping was associated with greater SWB. An intent to leave in the next year was reported by 5.4%. Emerging themes from qualitative data ( n = 22) included faith-informed or existential spirituality, work environment, and emotional/psychological stressors such as feeling overwhelmed or witnessing suffering and coping through self-care and spirituality. Dimensions of SWB included spiritually based coping and life’s meaning and purpose. Intent to leave was related to the work environment or travel distance. Discussion: A nurse’s spirituality offers a mechanism for coping with accumulated losses and grief encountered in clinical practice and in turn supports SWB.
Optimization of placement of piezoelectric wafers based on a hybrid model using pitch-catch and pulse-echo configurations
Authors: Saad Karen , Tarhini Hussein , Harb Mohammad S , Mustapha Samir
Published: June 2021

The development of Structural Health Monitoring (SHM) systems and integration in our structures is a necessity. It has proven to provide a robust and low-cost solution for monitoring structural integrity and can predict the remaining life of our structures. One of the most important aspects of SHM systems is the design and implementation of sensor networks. This study proposes a new hybrid model for optimizing sensor placement on convex and non-convex structures. We propose a novel framework in which two detection mechanisms are considered: pitch-catch and pulse-echo to provide coverage for a given surface. These two mechanisms will complement each other to minimize the number of sensors used while maintaining a high coverage. This combination also allows for better coverage of the corners and regions in the proximity of geometrical discontinuity (such as holes and openings). The monitored area is discretized into a set of control points. For a control point to be covered, it should satisfy the user-defined coverage level which is the number of sensing paths crossing that point. These sensing paths are provided by two modes of communications (pitch-catch and pulse-echo) between the actuator-sensor pairs. The model, which is solved using a genetic algorithm (GA), provides flexibility by allowing the user to input different parameters such as the attenuation distance of the propagating waves and the sensing path limits of both coverage configurations that can be determined through experimentation. The efficiency of the proposed model is then demonstrated by simulating different geometrical shapes. Significant improvement in the coverage of the monitored area, reaching 34.6%, was achieved when compared to the coverage provided by some preliminary solutions such as uniformly placing the sensors on the plate under study. Also, the advantage of combining both configurations (pitch-catch and pulse-echo) in the same model was investigated. It was shown that the latter highly impacted the coverage in the blind zones (corners and edges) where a single configuration is not effective. Afterward, experimental validation was carried out to evaluate the model’s accuracy in damage localization within the optimized sensor networks. The results demonstrated the proficiency of the model developed in distributing the sensors on the tested specimens.
Promoting Gender Inclusivity in General Music: Considerations for Music Listening
Authors: Robison Tiger , Culp Mara E.
Published: June 2021

General music teachers can promote gender inclusivity in music classrooms through music listening activities. Helping all students feel included and honored could improve student learning and foster continued and diversified music listening in school and beyond. The purpose of this article, the first of three about gender inclusivity in general music, is to help music teachers create inclusive general music experiences to support all students during music listening activities. By knowing learners as individuals, teachers can help all students feel valued in music classrooms, which may serve to deepen and extend their music listening skills and preferences.
Venous Thromboembolism Prophylaxis in Underweight Hospitalized Patients
Authors: Buckheit Douglas , Lefemine Amanda , Sobieraj Diana M. , Hobbs Laura
Published: June 2021

There is limited evidence about optimal anticoagulant dosing for venous thromboembolism (VTE) prophylaxis in underweight patients. The purpose of this study was to characterize dosing strategies used in underweight patients and compare the incidence of bleeding and VTE to patients receiving a standard dose. This multi-center retrospective study evaluated medicine patients who weighed 45 kilograms or less and received VTE prophylaxis with unfractionated heparin or enoxaparin. We categorized subjects into groups as either standard or reduced dose and compared the incidence of bleeding and VTE between groups. Of the 300 patients included in the outcome analysis, 40.7% received a reduced dose regimen, most often enoxaparin 30 mg daily. Standard dose was associated with major bleeding compared with reduced dose, when adjusted for age, gender and admission hemoglobin (odds ratio 4.73, 95% confidence interval 1.05 to 21.34). Incidence of clinically relevant non-major bleeding (2.4% vs. 1.1%) and VTE (0.6% vs. 0%) were similar between groups. Anticoagulant dose reduction for VTE prophylaxis in underweight hospitalized medicine patients is common practice and associated with less major bleeding.
Race-Based Sexual Stereotypes, Gendered Racism, and Sexual Decision Making Among Young Black Cisgender Women
Authors: Bond Keosha T. , Leblanc Natalie M. , Williams Porche , Gabriel Cora-Ann , Amutah-Onukagha Ndidiamaka N.
Published: June 2021

Background. Due to their intersecting racial identity and gender identity, Black women are characterized by stigmatizing race-based sexual stereotypes (RBSS) that may contribute to persistent, disproportionately high rates of adverse sexual and reproductive health outcomes. RBSS are sociocognitive structures that shape Black women’s social behavior including their sexual scripts. Objective. The purpose of this study was to explore the influence of RBSS on the sexual decision making of young Black women (YBW). Methods. We conducted four focus groups with 26 YBW between the ages of 18 and 25, living in a New York City neighborhood with a high HIV prevalence. Qualitative analysis was used to identify emergent themes within the domains of sexual decision making as it relates to safer sex practices and partner selection. Results. Thematic analyses revealed that RBSS may cause women to adopt more traditional gender stereotypes and less likely to feel empowered in the sexual decision making. Participants reported that RBSS may lead Black women to being resistant to learning new information about safer sex practices, feeling less empowered within intimate relationships, and jeopardizing their sexual well-being to affirm themselves in other social areas encouraging unprotected sex and relationships with men who have multiple sex partners. Discussion and Conclusion. Future research should focus on understanding the social and cultural factors that influence Black women’s power in maintaining and improving their sexual health, including the aforementioned stereotypes that have influenced how others may view them as well as how they view themselves.
El Nacimiento del Pueblo Mestizo: Critical Discourse on Historical Trauma, Community Resilience and Healing
Authors: Cacari Stone Lisa , Avila Magdalena , Duran Bonnie
Published: June 2021

Purpose. Historical trauma has been widely applied to American Indian/Alaska Native and other Indigenous populations and includes dimensions of language, sociocultural, and land losses and associated physical and mental disorders, as well as economic hardships. Insufficient evidence remains on the experiences of historical trauma due to waves of colonization for mixed-race Mexican people with indigenous ancestry (el pueblo mestizo). Research Question. Drawing from our critical lenses and epistemic advantages as indigenous feminist scholars, we ask, “How can historical trauma be understood through present-day discourse of two mestizo communities? What are public health practice and policy implications for healing historical trauma among mestizo populations?” Methodology and Approach. We analyzed the discourse from two community projects: focus groups and ethnographic field notes from a study in the U.S.–Mexico border region (2012–2014) and field notes and digital stories from a service-learning course in northern New Mexico (2016–2018). Findings. Our analysis describes the social and historical experiences of Mexicans, Mexican Americans, Chicanas/os, and Nuevo Mexicano peoples in the southwestern border region of the United States. We found four salient themes as manifestations of “soul-wound”: (1) violence/fear, (2) discrimination/shame, (3) loss, and (4) deep sorrow. Themes mitigating the trauma were community resiliency rooted in “querencia” (deep connection to land/home/people) and “conscientizacion” (critical consciousness). Conclusion. Historical trauma experienced by mestizo Latinx communities is rooted in local cultural and intergenerational narratives that link traumatic events in the historic past to contemporary local experiences. Future public health interventions should draw on culturally centered strength-based resilience approaches for healing trauma and advancing health equity.
Research From a Diné-Centered Perspective and the Development of a Community-Based Participatory Research Partnership
Authors: Werito Vincent , Belone Lorenda
Published: June 2021

Purpose. Indigenous ( Diné) communities have long endured high rates of behavioral and mental health diseases like depression, drug and alcohol dependency, and suicide due to historical trauma and posttraumatic stress disorders. Western research methods used to address these issues have often failed to provide sufficient understanding of the culturally nuanced dynamics underpinning these health disparities in Indigenous contexts. As a result, Indigenous health disparities have actually increased and complex culture-based relationships that influence health outcomes are underconceptualized. Aim. For the first time a community-based participatory research approach from a Diné perspective is introduced to three Navajo communities in New Mexico to collaboratively explore their perspectives about community-engaged research and community well-being from a Diné lens. The overarching research question was: Can a community-based participatory research approach embedded within a Diné research paradigm be utilized to develop a culturally centered intervention approach? Methods. The study utilized a mixed method approach that included surveys and focus groups. Results. Six overarching themes emerged that underscored the important role of utilizing a community-based participatory Diné-centered approach to define community well-being and increase community agency to address their own health disparities. Conclusion. Indigenous-centered community-engaged research can potentially become an intervention approach for informing Indigenous communities’ understandings of well-being by drawing upon local cultural Indigenous knowledge. This study demonstrated that developing an effective community-engaged research partnership to address health disparities in a Diné context must be informed by a Diné paradigm grounded in local community cultural knowledge.
Modeling Golfers’ Revisit Intention: An Application of the Theory of Reasoned Action
Authors: Song Hui-min , Chen Jamie M. , Zeng Ting-ting , Kim Brian H.
Published: June 2021

Based on the theory of reasoned action, this study examines the factors that affect the revisit intention of Chinese golfers. It focuses on the mediating effects of place attachment on the golfers’ perception of golf-course employee attitudes and destination distinctiveness. To test the conceptual model, a survey of 494 Chinese golfers was conducted using factor analyses and structural equation modeling. The article further applied a bootstrapping method to test the mediating effects of place attachment. The results indicate that the revisit intention was influenced by the golfers’ perceptions of employee attitudes, destination distinctiveness, and place attachment. It was also found that place attachment mediated these relationships. Finally, the theoretical contributions and industrial implications were discussed.
Genotype-phenotype correlations in ocular manifestations of Marinesco–Sjögren syndrome: Case report and literature review
Authors: Bayram Nurettin , Kaçar Bayram Ayşe , Daimagüler Hülya-Sevcan , Dafsari Hormos Salimi , Bamborschke Daniel , Uyanik Gökhan , Erdogan Murat , Özsaygılı Cemal , Pangal Emine , Yuvaci İsa , Doğanay Selim , Gümüş Hakan , Per Hüseyin , Jungbluth Heinz , Çırak Sebahattin
Published: June 2021

Purpose:

This study aims to present a family with two children with MSS who presented with different ophthalmic features. We also aim to review MSS patients’ ocular manifestations to provide a basis for future clinical trials and improve MSS patients’ ophthalmologic care.

Case description:

Both patients presented with global developmental delay, microcephaly, cerebellar ataxia, and myopathy. The older sibling had developed bilateral cataracts at the age of six. Her 2 years younger sister interestingly showed bilateral hyperopic refractive error without cataracts yet. Mendeliome sequencing unraveled a novel homozygous frameshift mutation in the SIL1 gene ( SIL1, NM_022464.5, c.1042dupG, p.E348Gfs*4), causing MSS. A systematic literature review revealed that cataracts appear in 96% of MSS cases with a mean onset at 3.2 years. Additional frequent ocular features were strabismus (51.6%) and nystagmus (45.2%).

Conclusion:

SIL1-related MSS is associated with marked clinical variability. Cataracts can develop later than neuromuscular features and cognitive signs. Since cataract is a relatively late finding, patients may refer to ophthalmologists for other reasons such as refractive errors, strabismus, or nystagmus. Molecular genetic testing for SIL1 is essential to facilitate early diagnosis in patients with suspected MSS.
Partisans use emotions as social pressure: Feeling anger and gratitude at exiters and recruits in political groups
Authors: Delton Andrew W , Kane John V , Petersen Michael Bang , Robertson Theresa E , Cosmides Leda
Published: June 2021

Political collective action requires assembling and motivating supporters. Many theories view emotions as functional tools for managing relationships, including within groups. We study what leads citizens to use the emotions anger and gratitude as social pressure. Specifically, we test what determines the use of these emotions to prevent potential exiters from leaving a political group and to encourage potential recruits to join. Because parties are enduring social affiliations (compared to transient or issue-focused groups), we predicted that partisans would express stronger emotions. We tested this proposition in two separate studies—one an observational study featuring a representative sample of US adults and one an experimental study conducted in Denmark. As predicted, people with a partisan mindset, whether naturally occurring or experimentally manipulated, felt more anger and gratitude at potential exiters and recruits. Citizens strive to fortify and expand their ingroups and sometimes use emotions as social pressure to do so.
Gender differences between adolescents with autism in emergency psychiatry
Authors: So Pety , Wierdsma André I , van Boeijen Christine , Vermeiren Robert RJM , Mulder Niels CL
Published: June 2021

Adolescents, particularly those with autism spectrum disorders, increasingly use psychiatric emergency services. Such risk is further greater in girls. Available knowledge on young people with autism during crises lacks understanding of gender differences and of differences between typically developing adolescents and adolescents with autism. After psychiatric emergency consultations, we therefore compared the symptomatology and comorbidity of girls and boys with autism, and also to their typically developing male and female counterparts. We used registry data (2009–2017) on 1378 adolescents aged 12–18 years referred for urgent consultation to mobile psychiatric emergency services. This showed an increase in diagnoses of autism spectrum disorder from 7.9% in 2009 to 18.1% in 2016; autistic girls showed a steeper increase than autistic boys. A higher percentage of girls than boys with autism presented with comorbid anxiety disorders and a higher risk of suicide or self-harm, while the persistence of their complaints over time was rated lower. Adolescents with autism experienced more severe impairment in overall functioning, while being diagnosed less often with comorbid disorders as compared to typically developing adolescents. Outpatient care for autistic youth should include easy access to specialized professionals to help young people with autism cope with the challenges of adolescence.

Lay abstract

Among adolescents seen for psychiatric emergency consultation, the percentage of adolescents with autism is increasing over the years. This applies even more to girls than to boys. We collected data of 1378 adolescents aged 12–18 years who were seen for urgent consultation by mobile psychiatric emergency services in the Netherlands. Among these, there were 64 autistic girls and 125 autistic boys. We wanted to know more about differences in problems between autistic and typical developing adolescents in crisis, both to prevent crisis and to improve services. The percentage of adolescents with autism increased over the years studied. Autistic adolescents experienced more severe impairment in functioning compared to typically developing adolescents. Compared to other adolescents, both boys and girls on the autism spectrum were diagnosed less frequently with mood disorders, behavioral disorders, relational problems, and abuse. Autistic girls had a higher suicide risk and suffered more often from anxiety disorders than autistic boys, while autistic boys had a longer history of problems. Outpatient care for children with autism should include easy access to specialized professionals who aim to reduce anxiety and help young people with autism to cope with the challenges of adolescence. Because possibly signs were missed during the emergency consultation, we recommend that as part of the routine procedure in crisis situations adolescents with autism are asked about mood and behavioral problems explicitly, as well as about negative life events.
Theresa May’s disjunctive premiership: Choice and constraint in political time
Authors: Byrne Chris , Randall Nick , Theakston Kevin
Published: June 2021

Theresa May’s premiership is widely acknowledged to have been a failure, but political commentators and the scholarly literature have, thus far, tended to focus on May’s misuse of her agency. This article argues that May’s premiership presents a particularly powerful example of the need to disentangle structure and agency when assessing prime ministerial performance. Drawing upon the work of Stephen Skowronek, it sets out a framework of evaluating prime ministerial agency in ‘political time’. This is then used to show how the conditions and circumstances in which May governed limited the feasibility, increased the costs, and compromised the effectiveness of her actions in office. We argue that this confirms that May was a victim of circumstances as much as a victim of her own agency.
Post-digital prosumption and the sharing economy of space: The pay-per-minute cafe
Authors: Kviat Alexandra
Published: June 2021

Although prosumption and the sharing economy are currently at the cutting edge of consumer culture research, little attempt has been made to explore the theoretical relationship between these concepts and approach them with a pluralistic, dynamic, nuanced and ethnographically informed lens moving beyond the dichotomies of capitalism versus anti-capitalism, rhetoric versus reality, exploitation versus empowerment and traditional versus digital consumer culture. This article addresses these gaps by focusing on the phenomenon of pay-per-minute cafes – physical spaces inspired by digital culture and meant to apply its principles in the brick-and-mortar servicescape. Drawing on a multi-site, multi-method case study of the world’s first pay-per-minute cafe franchise, the article shows a multitude of ways in which prosumption and the sharing economy, both shaped by different configurations of organisational culture, physical design, food offer and pricing policy, are conceived, interpreted and experienced by the firms and customers across the franchise and argues that conflicts and contradictions arising from this diversity cannot be reduced to the narrative of consumer exploitation. Finally, while both prosumption and the sharing economy are typically defined by the use of digital platforms, this article makes a case for a post-digital approach to consumer culture research, looking into the cultural impact of digital technology on traditional servicescapes.
A Pilot Fruit and Vegetable Prescription (FVRx) Program Improves Local Fruit and Vegetable Consumption, Nutrition Knowledge, and Food Purchasing Practices
Authors: Slagel Nicholas , Newman Taylor , Sanville Laurel , Thompson Jennifer Jo , Dallas Jackie , Cotto-Rivera Edda , Lee Jung Sun
Published: June 2021

Fruit and Vegetable Prescription (FVRx) programs rely on diverse community and clinic partnerships to improve food security and fruit and vegetable consumption among medically underserved patient populations. Despite the growth in these programs, little is known about the feasibility or effectiveness of the unique partnerships developed to implement FVRx programs conducted in both community and free safety-net clinic settings. A 6-month nonrandomized controlled trial of an FVRx program was pilot tested with 54 Supplemental Nutrition Assistance Program (SNAP)–eligible adults with diet-related chronic conditions. The intervention combined monthly produce prescriptions for local produce at a farmers market, SNAP-Ed direct nutrition education, and health screenings for low-income adults. Process and outcome evaluations were conducted with respective samples using administrative program data (recruitment, retention, and prescription redemption) and self-administered pre- and postintervention surveys with validated measures on dietary intake, nutrition knowledge and behavior, and food purchasing practices. Descriptive statistical analyses were conducted. The FVRx program retained 77.3% of participants who spent nearly 90% of their prescription dollars. After the intervention, the FVRx group reported significantly increased total intake of fruits and vegetables, knowledge of fresh fruit and vegetable preparation, purchase of fresh fruits and vegetables from a farmers market, and significantly altered food purchasing practices compared with the control group. Community-based nutrition education organizations enhance the feasibility and effectiveness of community and clinic-based FVRx programs for improving low-income adults’ ability to enhance food and nutrition-related behaviors.
The Effect of Psychiatric History on Pain and Related Outcomes Among Living Kidney Donors
Authors: Fox Kristen R. , Gulin Shaina L. , Bruschwein Heather M. , Rose Terra , Burker Eileen J. , Kozlowski Tomasz , Loiselle Marci M.
Published: June 2021

Introduction:

Living donor transplantation of kidneys accounts for one quarter of transplants performed in the United States. Careful screening of psychiatric history is a standard part of the donor evaluation. Little is known about the impact of psychiatric history on post-donation course and pain experience.

Research Question:

This study investigated whether psychiatric history was associated with pain and related outcomes among living kidney donors.

Design:

A retrospective medical record review was conducted of 75 living kidney donors who underwent laparoscopic donor nephrectomy. All donor candidates completed a psychological evaluation and were approved for donation by a multidisciplinary committee. History of psychiatric diagnosis and psychiatric medication use were obtained from donors’ psychological evaluation reports. Data on pain and related outcomes (ie, history of prescribed pain medication, post-donation pain, opioid use, length of hospital stay, post-donation emergency department visits), as well as demographic and donation-related characteristics were also abstracted from medical records.

Results:

Psychiatric history, including current or historical psychiatric diagnosis or psychiatric medication use, in living kidney donors who were evaluated and approved for donation by a transplant psychologist was not associated with greater perceived pain, greater use of opioid pain medication in the post-operative period, longer hospital stays, or more frequent post-donation emergency department visits.

Discussion:

The findings demonstrate that carefully screened donors with a psychiatric history have comparable pain-related outcomes as donors without a psychiatric history. This study highlights the importance of the pre-donation psychological evaluation in promoting positive postdonation outcomes through careful selection of donor candidates.
Supporting Families with Children Who Display Severe Challenging Behavior
Authors: Durand V. Mark
Published: June 2021

Over the past several decades, we have developed quality behavioral assessments and interventions for challenging behaviors among individuals with a variety of severe developmental and cognitive disorders. These assessments and interventions have been used to educate family members on how to understand and intervene with these behaviors at home and in community settings. However, it has become clear that many families are not able to carry out these procedures adequately. This case describes recent work that is designed to support families so that they can assist their challenging children. Fortunately, we have been able to demonstrate a way of looking at parental difficulties and have designed interventions for families so that they are better able to implement successful behavioral assessments and interventions. We will describe a concession process that can help explain these parental obstacles and can aid with creating specific supports to assist families struggling with these difficulties. We also discuss future directions for follow-up research.
Depression Diagnosis Modeling With Advanced Computational Methods: Frequency-Domain eMVAR and Deep Learning
Authors: Uyulan Caglar , de la Salle Sara , Erguzel Turker T. , Lynn Emma , Blier Pierre , Knott Verner , Adamson Maheen M. , Zelka Mehmet , Tarhan Nevzat
Published: June 2021

Electroencephalogram (EEG)-based automated depression diagnosis systems have been suggested for early and accurate detection of mood disorders. EEG signals are highly irregular, nonlinear, and nonstationary in nature and are traditionally studied from a linear viewpoint by means of statistical and frequency features. Since, linear metrics present certain limitations and nonlinear methods have proven to be an efficient tool in understanding the complexities of the brain in the identification of underlying behavior of biological signals, such as electrocardiogram, EEG and magnetoencephalogram and thus, can be applied to all nonstationary signals. Various nonlinear algorithms can be used in the analysis of EEG signals. In this research paper, we aim to develop a novel methodology for EEG-based depression diagnosis utilizing 2 advanced computational techniques: frequency-domain extended multivariate autoregressive (eMVAR) and deep learning (DL). We proposed a hybrid method comprising a pretrained ResNet-50 and long-short term memory (LSTM) to capture depression-specific information and compared with a strong conventional machine learning (ML) framework having eMVAR connectivity features. The following 8 causality measures, which interpret the interaction mechanisms among spectrally decomposed oscillations, were used to extract features from multivariate EEG time series: directed coherence (DC), directed transfer function (DTF), partial DC (PDC), generalized PDC (gPDC), extended DC (eDC), delayed DC (dDC), extended PDC (ePDC), and delayed PDC (dPDC). The classification accuracies were 84% with DC, 85% with DTF, 95.3% with PDC, 95.1% with gPDC, 84.8% with eDC, 84.6% with dDC, 84.2% with ePDC, and 95.9% with dPDC for the eMVAR framework. Through a DL framework (ResNet-50 + LSTM), the classification accuracy was achieved as 90.22%. The results demonstrate that our DL methodology is a competitive alternative to the strong feature extraction-based ML methods in depression classification.
Three perspectives on parental support in youth soccer: Children, parents, and coaches
Authors: Lobinger Babett H , Eckardt Valeria C , Lautenbach Franziska
Published: June 2021

The aim of the research project was to gain an in-depth understanding of how children, coaches, and parents in youth soccer perceive parental support. In a preliminary study, a questionnaire was developed to assess satisfaction with parental support and sideline behavior in soccer. The multisection questionnaire was adapted to all three parties of interest—children, parents, and coaches—and administered to 260 parents, 196 coaches, and 111 male players aged 12–14 years across different clubs to identify factors influencing satisfaction with parental behavior across all three groups. Factor analysis led to a revised version of the questionnaire, emphasizing the importance of emotional support. The revised questionnaire was implemented in two consecutive field studies. Samples were drawn from an amateur youth soccer setting (Study 2, N = 316, players aged 8–13 years) and a professional youth academy (Study 3, N = 209, players aged 9–16 years). Overall, results indicate children and parents were highly satisfied with parental support and sideline behavior but coaches’ satisfaction differed significantly. The discussion therefore includes all three perspectives and provides recommendations on how to improve the coach–parent relationship and professional engagement with parents.
Practitioner perspectives of athlete recovery in paralympic sport
Authors: Szabo Sara W , Kennedy Michael D
Published: June 2021

Athlete health and sport performance research for athletes with disabilities has increased substantially over the years as the level of competition and intensity in Paralympic sport has grown. However, relative to able-bodied sport, there remains some key areas of parasport research which are distinctly lacking. Athlete recovery, as a counterbalance to training stress and an important factor in preventing adverse health consequences such as illness and injury, is one of these understudied areas for elite para-athletes. Thus, the purpose of this descriptive qualitative study was to understand factors impacting recovery among Paralympic athletes, based on practitioner perspectives, with the aim of providing insightful guidance for applied practice. Semi-structured interviews were conducted with 15 North American sport practitioners who worked with elite para-athletes. Through thematic analysis, five main themes about optimizing athlete recovery in various populations of para-athletes were developed: a) prioritize the simple concepts, b) get to know the whole athlete, c) experience matters, d) musculoskeletal factors, and e) non-training load. Collectively, these results highlight how humanistic approaches to care, augmented by individual athlete expertise, extensive education, and a consideration of fundamental lifestyle factors is exceedingly important for para-athlete recovery. This study further describes that the approach to recovery among para-athletes, a diverse population, is uniquely complex from that of able-bodied sport and warrants scholarly attention.
‘Youthification’ of drama through real-time storytelling: A production study of blank and the legacy of SKAM
Authors: Sundet Vilde Schanke
Published: June 2021

This article explores the ‘youthification’ of television through real-time storytelling. It draws on a study of the online youth drama blank (2018–2019), NRK’s first follow-up after the hit show SKAM (2015–2017). It finds that real-time drama brings unique opportunities to broadcasters aiming to reconnect with younger audiences, but also substantial challenges. This insight is essential, as previous studies have highlighted the format’s advantages while downplaying its problems and dilemmas. Furthermore, the article emphasises the continuous need for innovation in youth storytelling, especially at public service broadcasters with the mandate and ability to do so.
Risk factors for new-onset atrial fibrillation during critical illness: A Delphi study
Authors: Bedford Jonathan P , Garside Tessa , Darbyshire Julie L , Betts Timothy R , Young J Duncan , Watkinson Peter J
Published: June 2021

Background

New-onset atrial fibrillation (NOAF) is common during critical illness and is associated with poor outcomes. Many risk factors for NOAF during critical illness have been identified, overlapping with risk factors for atrial fibrillation in patients in community settings. To develop interventions to prevent NOAF during critical illness, modifiable risk factors must be identified. These have not been studied in detail and it is not clear which variables warrant further study.

Methods

We undertook an international three-round Delphi process using an expert panel to identify important predictors of NOAF risk during critical illness.

Results

Of 22 experts invited, 12 agreed to participate. Participants were located in Europe, North America and South America and shared 110 publications on the subject of atrial fibrillation. All 12 completed the three Delphi rounds. Potentially modifiable risk factors identified include 15 intervention-related variables.

Conclusions

We present the results of the first Delphi process to identify important predictors of NOAF risk during critical illness. These results support further research into modifiable risk factors including optimal plasma electrolyte concentrations, rates of change of these electrolytes, fluid balance, choice of vasoactive medications and the use of preventative medications in high-risk patients. We also hope our findings will aid the development of predictive models for NOAF.
Effects of Cross-Education After 6 Weeks of Eccentric Single-Leg Decline Squats Performed With Different Execution Times: A Randomized Controlled Trial
Authors: Martínez Fernando , Abián Pablo , Jiménez Fernando , Abián-Vicén Javier
Published: June 2021

Background:

Cross-education of strength refers to the strength gain that is transferred to the contralateral limb after a unilateral training program.

Hypothesis:

Unilateral eccentric training using different muscle contraction times would improve the structural and functional properties of the untrained contralateral limb.

Study Design:

Randomized controlled trial.

Level of Evidence:

Level 2.

Methods:

Thirty-six participants were randomized into a control group, experimental group 1 (EG6s; eccentric contraction runtime = 6 seconds) and experimental group 2 (EG3s; eccentric contraction runtime = 3 seconds). The thickness and elastographic index of the patellar tendon (PT), lean mass and fat percentage of the thigh, contractile properties of the vastus lateralis (VL), as well as isometric, concentric, and eccentric knee extensor peak torques, and eccentric single-leg decline squat (SLDSe) 1 repetition maximum (1-RM) were measured after 6 weeks of SLDSe training (3 times per week, 80% of 1-RM) and after 6 weeks of detraining in the untrained contralateral limb.

Results:

After training, there was an increase in lean thigh mass of the untrained limb in both groups: EG6s (0.17 ± 0.29 kg; P = 0.03; effect size [ES] = 0.15) and EG3s (0.15 ± 0.23 kg; P = 0.04; ES = 0.19). Likewise, both EG6s (62.30 ± 19.09 kg; P < 0.001; ES = 4.23) and EG3s (68.09 ± 27.49 kg; P < 0.001; ES = 3.40) increased their 1-RM, isometric (EG6s: 48.64 ± 44.82 N·m, P < 0.001, ES = 0.63; EG3s: 34.81 ± 47.30 N·m, P = 0.004, ES = 0.38), concentric at 60 deg/s and 180 deg/s and eccentric at 60 deg/s and 180 deg/s knee extensor peak torques ( P < 0.05) in the untrained limb. However, no differences were found in the contractile properties of the VL or in the thickness of the PT after eccentric training in either of the 2 experimental groups.

Conclusion:

Regardless of the runtime of the contraction, 6 weeks of SLSDe was effective for inducing structural and strength adaptations in the contralateral untrained limb. However, most of these adaptations were lost after 6 weeks of detraining.

Clinical Relevance:

Our study suggests that cross-education training can be of great importance for clinical application and musculoskeletal and neuromuscular rehabilitative processes after unilateral injury.
Baclofen therapeutics, toxicity, and withdrawal: A narrative review
Authors: Romito Jia W , Turner Emily R , Rosener John A , Coldiron Landon , Udipi Ashutosh , Nohrn Linsey , Tausiani Jacob , Romito Bryan T
Published: June 2021

Baclofen is an effective therapeutic for the treatment of spasticity related to multiple sclerosis, spinal cord injuries, and other spinal cord pathologies. It has been increasingly used off-label for the management of several disorders, including musculoskeletal pain, gastroesophageal reflux disease, and alcohol use disorder. Baclofen therapy is associated with potential complications, including life-threatening toxicity and withdrawal syndrome. These disorders require prompt recognition and a high index of suspicion. While these complications can develop following administration of either oral or intrathecal baclofen, the risk is greater with the intrathecal route. The management of baclofen toxicity is largely supportive while baclofen withdrawal syndrome is most effectively treated with re-initiation or supplementation of baclofen dosing. Administration of other pharmacologic adjuncts may be required to effectively treat associated withdrawal symptoms. This narrative review provides an overview of the historical and emerging uses of baclofen, offers practical dosing recommendations for both oral and intrathecal routes of administration, and reviews the diagnosis and management of both baclofen toxicity and withdrawal.
Greater trochanteric pain syndrome: Evaluation and management of a wide spectrum of pathology
Authors: Pianka Mark A , Serino Joseph , DeFroda Steven F , Bodendorfer Blake M
Published: June 2021

Greater trochanteric pain syndrome is a common cause of lateral hip pain, encompassing a spectrum of disorders, including trochanteric bursitis, abductor tendon pathology, and external coxa saltans. Greater trochanteric pain syndrome is primarily a clinical diagnosis, and careful clinical examination is essential for accurate diagnosis and treatment. A thorough history and physical exam may be used to help differentiate greater trochanteric pain syndrome from other common causes of hip pain, including osteoarthritis, femoroacetabular impingement, and lumbar stenosis. Although not required for diagnosis, plain radiographs and magnetic resonance imaging may be useful to exclude alternative pathologies or guide treatment of greater trochanteric pain syndrome. The majority of patients with greater trochanteric pain syndrome respond well to conservative management, including physical therapy, non-steroidal anti-inflammatory drugs, and corticosteroid injections. Operative management is typically indicated in patients with chronic symptoms refractory to conservative therapy. A wide range of surgical options, both open and endoscopic, are available and should be guided by the specific etiology of pain. The purpose of this review is to highlight pertinent clinical and radiographic features used in the diagnosis and management of greater trochanteric pain syndrome. In addition, treatment indications, techniques, and outcomes are described.
Morally Motivated Networked Harassment as Normative Reinforcement
Authors: Marwick Alice E.
Published: June 2021

While online harassment is recognized as a significant problem, most scholarship focuses on descriptions of harassment and its effects. We lack explanations of why people engage in online harassment beyond simple bias or dislike. This article puts forth an explanatory model where networked harassment on social media functions as a mechanism to enforce social order. Drawing from examples of networked harassment taken from qualitative interviews with people who have experienced harassment ( n = 28) and Trust & Safety workers at social platforms ( n = 9), the article builds on Brady, Crockett, and Bavel’s model of moral contagion to explore how moral outrage is used to justify networked harassment on social media. In morally motivated networked harassment, a member of a social network or online community accuses a target of violating their network’s norms, triggering moral outrage. Network members send harassing messages to the target, reinforcing their adherence to the norm and signaling network membership. Frequently, harassment results in the accused self-censoring and thus regulates speech on social media. Neither platforms nor legal regulations protect against this form of harassment. This model explains why people participate in networked harassment and suggests possible interventions to decrease its prevalence.