bluuebunny/crossref_metadata_2025 huggingface dataset:
The diagnostic value of nerve growth factor and c-reactive protein in patients with interstitial cystitis / painful bladder syndrome
Authors: Sholan Rashad F.
Published: August 2020

Objective: to determine the diagnostic value of nerve growth factor (NGF) and C-reactive protein (CRP) in patients with interstitial cystitis / painful bladder syndrome (IC/BPS).

Material and methods. 44 patients with IC/BPS (main group) and 20 volunteers (control group) were examined. The average age of the patients of the main group was 46.4 13.9 years, the control group 35.3 9.7 years. Cystoscopy and hydrodistension of the bladder were performed. The severity of pain was evaluated on a visual analogue scale (VAS). The concentration of NGF was determined in the blood by the method of ELISA, CRP by the immunoturbidimetric method.

Results. The average total score on the VAS scale was 5.47 0.91, mild pain (24 points) was noted by 20.4%, moderate pain (56 points) 54.5%, severe pain (78 points) 25.0% of patients. Diffuse bleeding of the bladder mucosa in 45.4% of cases was observed. In IC/BPS patients the average NGF level was 11.23 8.22 ng/ml, CRP 3.56 1.66 mg/l. The concentration of NGF exceeded the control level by 22.7% (p 0.05), CRP by 71.3% (p = 0.015). The correlation coefficient of NGF with CRP was r = + 0.179 (p = 0.42), and the determination coefficient was R2 = 0.032.

Conclusion. Identified statistically significantly increased levels of NGF and CRP in the blood serum of IC/BPS patients confirm the presence of a systemic inflammatory reaction. A weak direct correlation is determined between NGF and CRP in patients with IC/BPS patients. The determination of serum NGF and CRP in combination with clinical data can be used to diagnose IC/ BPS.
TINJAUAN ”TREND FORECASTING” PADA INDUSTRI DESAIN INTERIOR INDONESIA
Authors: Suroso putro Tunjung Atmadi
Published: August 2020

Abstrak: Trend Forecasting dengan  tema "Singularity" terdapat empat subtema yaitu Exuberant, Neo Medieval, Svarga, dan Cortex. Tema Singularity terkait perubahan zaman, yakni gambaran suatu keadaan yang mengindikasikan beragam . Hal ini bertujuan untuk memunculkan desain yang baru yang laku dalam rangka memenuhi selera pasar. pergeseran teknologi dan sikap-sikap yang menyertainya, dan gambaran masa depan yang masih diraba. Metode yang digunakan dalam penelitian ini yaitu forecasting. Sebuah metode untuk memprediksi trend atau memproyeksikan trend untuk beberapa waktu kedepan. Hasil dari penelitian ini menjadi bagian yang sangat penting dari perkembangan industri interior Indonesia. Dan diharapkan bisa menjadi rujukan bagi pelaku industri, desainer, maupun akademisi bidang desain interior untuk mendapatkan referensi dan inspirasi Indonesia.
Female Gaze pada Film “Lady Bird”
Authors: Langga Fathin Hanifah
Published: August 2020

Film box office Lady Bird mendapatkan banyak penghargaan dan review positif dari para kritikus.  Hal menarik yang dapat dibahas dari film Lady Bird adalah mengenai female gaze. Menganalisis dengan membandingkan teori Laura Mulvey mengenai female gaze dan male gaze melalui fenomena yang terdapat pada film Lady Bird yang menceritakan kehidupan seorang remaja perempuan pada umumnya. Image perempuan dalam film Lady Bird tidak tampak sebagai sebuah objek melainkan sebuah subjek, gaya pemeran perempaun dalam film Lady Bird tampil kuat, ambisius dan optimis. Lady Bird membuktikan bahwa teori Mulvey tentang dunia patriarkal tidak permanen dan tidak wajib.
El capital humano de la empresa: una propuesta de medición
Authors: Gallego-Giraldo Carmenza , Naranjo-Herrera Cristhian Guillermo
Published: August 2020

El presente artículo presenta una propuesta de medición del capital humano que integra los componentes, variables e indicadores determinados a partir de la investigación desarrollada en torno a la medición del capital humano de un conjunto de empresas colombianas.  Se llevó a cabo una investigación cuantitativa bajo el diseño de estudio de casos, en la que se recopiló la información mediante una encuesta aplicada a una muestra estadísticamente representativa de los empleados de los niveles estratégico, táctico y operativo de las empresas objeto de estudio y a través de la revisión de documentos y sistemas de información de recursos humanos de dichas empresas. Además, se efectuó una revisión de la literatura especializada en el capital humano en las bases de datos Scopus, Science Direct, Dialnet, Redalyc y Google Scholar. Los resultados muestran que las empresas indagadas desconocen los elementos que integran el capital humano y no cuentan con la trazabilidad de los datos de su personal que permitan medirlo. Se concluye que la medición del capital humano debe efectuarse a partir de cuatro componentes: conocimiento, valores compartidos, competencias laborales y tipología del personal, con base en los cuales se construyó una propuesta que incorpora, para cada uno de ellos, un conjunto de variables e indicadores para identificar y cuantificar este activo intangible e incrementar la efectividad de su gestión.
Excision of 93 loose bodies of synovial osteochondromatosis in the left ankle: a case report
Authors: Dradjat Respati S. , Pradana Ananto S. , Salim Fajar S. , Oktafandi I. Gusti Ngurah A. A.
Published: August 2020

Primary synovial osteochondromatosis is an uncommon benign joint disorder characterized by the formation of cartilaginous bodies within the synovial of the different joints, tendon sheaths, and bursae. Loose bodies occur in the late stage of the disease. Excision of loose bodies is needed to treat synovial osteochondromatosis. A 20-year-old female patient presented to us with a chief complaint of pain, swelling, and discomfort sensation in the left ankle while walking. Plain X-ray on her left ankle showed loose bodies surrounding the ankle. We performed excision to remove the loose bodies. Histological examination confirmed the diagnosis. The range of motion (ROM) of the ankle increased after surgery. The patient was able to walk more comfortably. Synovial osteochondromatosis is considered benign. In this case, open excision was chosen because the ankle joint is not amenable to arthroscopy. Follow up is needed to detect early recurrence and transformation of malignancy.
Acid corrosive injury of stomach: management and long-term outcome
Authors: Sharma Mohit , Singh Rachhpal
Published: August 2020

Background: Acid corrosive injury to stomach is not uncommon in India due to easy availability. Corrosive ingestion results in significant morbidity. We present our experience in surgical management of such cases. The aims and objectives of this study to review the experience of surgical management of gastric corrosive injury and to assess long term outcome and functional results.Methods: This study was retrospective analysis of prospectively collected data of 23 cases of acid corrosive injury managed in a single surgical unit.Results: Median age was 31 years, male to female ratio was 12:11. Surgical procedures were tailored according to extent and degree of stricture. Posterior gastrojejunostomy was done in 8 (38.0%) cases, near total gastrectomy in 3 (14.3%) cases, total gastrectomy and Billroth I in 2 (9.5%) cases each. 4 cases were lost to follow up after preliminary feeding jejunostomy. 2 cases had mortality after feeding jejunostomy. 2 cases were managed successfully without active surgical intervention. All patients undergoing definitive procedure had good results in terms of nutritional status and symptoms of gastric outlet obstruction.Conclusions: The outcome of gastric stricture secondary to acid ingestion can be significantly improved by adequate preoperative preparation and planned approach depending upon type of injury.
La maldición del ganador en los procesos de contratación publica en Colombia: un análisis desde la economía del comportamiento
Authors: Morales Quijano Santiago
Published: August 2020

El comportamiento de los oferentes en formatos de subasta ha sido un tema ampliamente abordado por la economía tradicional, cuyas teorías más prominentes, como la teoría de juegos, buscan predecir, desde el punto de vista normativo, la mejor estrategia que debiera seguirse a fin de maximizar la función de utilidad. Sin embargo, existe evidencia científica que demuestra que los oferentes, incluso en escenarios de contratación pública, se desvían sistemáticamente del comportamiento racional esperado y en lugar de obtener una utilidad al ganar una subasta, con posterioridad incurren en pérdidas. El presente trabajo busca brindar claridades sobre el fenómeno conocido como la maldición del ganador y de cómo su existencia y efectos en la contratación publica amplían el análisis del problema de las ofertas anormalmente bajas, proponiéndose una metodología tanto cualitativa como cuantitativa para su validación en los contratos de obra pública.
ATUAÇÃO DOS PROFISSIONAIS DE ENFERMAGEM NA PREVENÇÃO E CONTROLE DAS INFECÇÕES RELACIONADAS À ASSISTÊNCIA À SAÚDE
Authors: Silva Marcelo Flavio Batista da , Santana Jefferson Da Silva , Lima e Silva Caio Clayderman Ferreira de
Published: August 2020

As infecções relacionadas à assistência à saúde são um risco que ameaça a segurança do paciente, sendo causa de morbimortalidade, desafiando os avanços científico-tecnológicos e, mobilizando a atenção de profissionais, pesquisadores, organizações nacionais e internacionais que buscam a efetividade das medidas de prevenção e controle. O objetivo deste trabalho foi identificar o conhecimento produzido a respeito da temática. É uma revisão integrativa, que permite examinar estudos científicos de forma sistemática e abrangente.  No contexto dos serviços de saúde, destaca-se como uma das principais preocupações em relação à segurança do paciente e qualidade dos serviços a redução da incidência das Infecções Relacionadas à Saúde. Assim, vigilância, prevenção e controle têm se tornados complexos nas últimas décadas, devido ao impacto dessas infecções sobre letalidade hospitalar, duração da internação e custos. Apoiado nesse entendimento, este estudo apresenta como inovação a consideração de que a Educação Permanente em Saúde constitui-se em estratégia que respalda o desenvolvimento de ações de Educação em Saúde e Educação em Serviço, desde que sejam operacionalizadas por metodologias que promovam o empoderamento e a qualificação profissional e nisso entra o papel de educador do enfermeiro. Descritores: Controle de Doenças; Educação Permanente; Infecção Hospitalar; Prevenção de Doenças; Profissionais de Enfermagem.
OBESIDADE INFANTIL NO ÂMBITO DA ATENÇÃO PRIMÁRIA.
Authors: Faria Ezequiel Patricio de , Coutinho Fabio Gonçalves , Kandler Ingrid
Published: August 2020

A obesidade infantil é um dos maiores problemas de saúde pública no Brasil e no mundo e sua prevalência vem aumentando de forma significativa ao longo dos anos. Tal fato é motivo de preocupação, uma vez que a obesidade é um importante determinante para o surgimento de várias complicações e agravos à saúde ainda na infância e também na vida adulta. Assim, o objetivo geral deste estudo é contextualizar o papel da saúde pública na identificação, prevenção e controle da obesidade infantil no âmbito da atenção primária. E tem como objetivos específicos: analisar as principais causas da obesidade infantil; demonstrar a importância da participação dos pais na identificação, prevenção e controle da obesidade em seus filhos; propor medidas a serem adotadas na Atenção Básica em Saúde no intuito de prevenir e controlar a obesidade infantil. Apesar da escassez de estudos que abordam o papel da família e dos profissionais da atenção primária em saúde, foi possível identificar que essas figuras são fundamentais na prevenção e controle da obesidade infantil. A orientação, conscientização e o conhecimento são fatores importantíssimos a serem trabalhados, para tanto faz-se necessário estudos que demonstrem a importância dos profissionais da atenção primária na identificação do problema e na orientação dos pais e familiares quanto o controle e a prevenção uma vez que esta doença pode trazer complicações ao longo de toda a vida dessa criança.
The in situ ply elasticity and strength in laminated composites
Authors: Oleinikov A.I. , Kuzmina T.A.
Published: August 2020

When calculating thin-walled structures made of layered polymer composite materials (PCM), data obtained as data obtained from testing a corresponding separately cured unidirectional sheet is accepted as the elastic-strength characteristics of their monolayers. Properties of such sheet significantly differ from the characteristics of the monolayer polymerized and working together with adjacent layers of different orientations as part of a composite package. The article presents the results of solving the problem of determining the elastic and strength characteristics of monolayers according to the data of direct tensile — compression tests of PCM samples from witness parts. It considers PCM which monolayers have similar or diverse characteristics. Formulas are given for calculating the mechanical properties of monolayers as part of a multidirectional composite package. Comparison of calculation results with test data is carried out. The use of the actual characteristics of monolayers makes it possible to calculate the real behavior of the PCM in the structure, to link its verification and design calculations.
Religious Traditional Treatment of Epidemics: A Legacy From Acehnese Manuscripts
Authors: Fakhriati Fakhriati , Yusuf Choirul Fuad
Published: August 2020

Traditional medication practice roots widely across region. A number of less complex traditional medicine practices also operated within small and sometimes isolated groups based largely on local experience since the very long time ago. Historical contribution of traditional medicine as one of complementary or alternative therapy is unquestionably recognized amongst the people of the world-wide. The Acehnese manuscripts written by ulamas, aligned from Muslim prior generations within a care giver environment cannot be denied its existence. One of the important subject contents is related to traditional medication applied since the very past time. This paper describes traditional medication written in the Acehnese manuscripts, of which particularly might be useful for handling the virus appeared today. With the use of philological and historical approach, uses text and contextual analysis, the paper highlights some findings, that the three Acehnese manuscripts -- Ar-Rahmah Fi at-Tibb wa Al-Hikmah, a manuscript of Teungku Nurdin, and a manuscript of Teungku Amir -- explain traditional medical treatment preventing the disease outbreak. Historically, the Acehnese used traditional medication therapy by means of consuming herbs beside staying as close as possible to religion and intensifying prayer to God. Due to its practical function as one of effective therapy and the valuable cultural legacy, the Acehnese manuscripts of traditional medication need any professional preservation, conservation, and reproduction for enriching the Nusantara’s civilization.
Identification The Content of Lead (Pb), Mercury (Hg), Chlorophyll-a, and Cell Morphology of Seaweed Kappaphycus alvarezii in Bluto and Saronggi Water, Sumenep, Madura, East Java
Authors: Afrianti Aisyah , Nabilah Farah , Wahyadyatmika Reysa Sasmaya , Alamsjah Moch. Amin , Agustono Agustono , Manan Abdul , Rahardja Boedi Setya
Published: August 2020

Kappaphycus alvarezii is one of Indonesia's export commodities because it has high economic value as food and industry. One area in East Java which is the center of seaweed cultivation is Sumenep regency such as Saronggi and Bluto. Currently Sumenep Regency is an area for oil and gas exploration and exploitation. Types of pollutants resulting from these activities cause pollution in aquatic environments such as lead (Pb), mercury (Hg) and cadmium (Cd). The heavy metals found in the waters can be absorbed and accumulated in the seaweed thallus. The purpose of this research is to know the heavy metal content of Pb, Hg, Cd, chlorophyll-a, and cell morphology in E. cottonii in Bluto and Saronggi waters. This research is survey and descriptive research. The results showed that there are differences in heavy metal content of lead in E. cottonii, seawater, and sediments in Bluto waters and Saronggi waters. The waters of Bluto have a lower amount of chlorophyll-a than the Saronggi Waters. Cell wall thickness in E. cottonii in Saronggi Waters has thinner cell walls than Bluto waters. Measurement of water quality in Bluto and Saronggi waters through temperature, pH, salinity, brightness and DO parameters. The measurement results from both waters are not any striking difference and under optimal conditions.
Process Production of Fishball Using Design of Fishball Moulding Machine in The Center of Testing The Application of Fishery (BBP2HP), Jakarta.
Authors: Sultoni Adam , Subekti Sri
Published: August 2020

Meatball is round-shaped food which contains meat as the basic ingredient and it becomes an original Indonesian food. Meatball can be made or created manually by hand or meatball machine. In this the modern era, a lot of meatball sellers are using meatball machine in order to get a maximum  and desired meatball results therefore the meatball machine is needed to accelerate the production process, faster than manual process.Meatball machine can produce more meatball (1000 meatballs per day) compared with manual process which can only produce 200-400 meatballs per day.  This internship was carried out to learn the production design for fish meatball production in BBP2HP through Triple screw with horizontal model. It consists of three basic process such as preparation, installation, and trial phase. The equipments which are used in running this system are masks, welding goggles, gloves, electrode, work outfit, saw blades, hammers, grinders, electric drill, hacksaw, lathes, work shoes, and sigmat.   Meatball machine is designed with stainless steel and can easily be used. This machine has horizontal-shaped body (Length x Height x Wide = 848 x 500 x 313 mm), 200 watt electricity, 5 kilograms grinding capacity, and 120 meatballs per minute production speed. It is suitable for home scale production with low electricity to save the cost.
THE ANALYSIS OF SPEECHNOTE APPLICATION FOR MEASURING THE ACCURACY OF STUDENTS’ PRONOUNCIATION
Authors: Lestari Nurjanah Sri Eka , Mulyadi Dodi , Wijayatiningsih Testiana Deni
Published: August 2020

Technology, education, and internet have been one of education’s part in this era. Learning independently is one of the choice for many students, not only effective to get understand but also time effectiveness are some of the reasons. All the thing that we learnt in the school is how to improve speaking, listening, writing, and reading skill. That’s why pronunciation become hidden subject which students don’t have to learn it. The problem in our education is English still foreign language for us, so it would be difficult to learn pronunciation autonomuosly or independently. Speechnote is one of the application which was created by WellSource for dictating spoken language to written language with high accuracy. The application helped students to learn pronunciation independently without being watched by the expert. The used method is descriptive-kualitatife and data collective which are recording and filling out questionnaire by 36 participants of students X.IS-1 SMA N 15 Semarang. The result of this research are the error of aplication, the accuracy of recording,recognizing misspronunciation, and the connection of increasing pronunciation by using speechnote.
Effectively Of 17α-Methyltestosterone on Tropical Eel, Anguilla bicolor McClelland Masculinization in Different Salinity Culture
Authors: Rachmawati Farida Nur , Affandi Ridwan , Sistina Yulia
Published: August 2020

Eel population in nature reaches critical number, so that culture strategy is urgently needed to fulfil the high demand of this fish. A shortcut to get functional male, which proven difficult to be founded from natural catching, is masculinization. This research aimed to induce masculinization of tropical eel, Anguilla bicolor McClelland supplemented with various doses of 17α-methyltestosterone during a month culture in freshwater (0 ppt) or brackish water (10 ppt).  The eel was grouped and fed with supplementation of 17α-methyltestosterone at various doses, depending upon treatments, namely 0 mg Kg-1 diet (control), 40, 80 or 120 mg Kg-1 diet. Eels size were similar, at approximately 16,78 g ± 0,62 in weight and 25,38 cm ± 0,15 in length were either culture in freshwater or brackish during the experiment for eight weeks. Sex gonad, based on anatomical histological structures, Eye Index and Fin Index were measured after time culture treatment achieved, as well as body length, weight, eye diameter and the length of the pectoral fin were measured. Results showed that supplementation 17α-methyltestosterone 80 mg/Kg diet culture in brackish water has the highest number of male (90%).  This study proven that, the hormone was effective for masculinization in eels, It useful for masculinization in eels. Results proved that the 17α-methyltestosterone highly significant (P<0.01) effect on the Eye index (3.63 – 5.14) and Fin Index (3.03 – 4.08) of eels. This study concluded, that 17α-methyltestosterone more effective in improving the number of males in brackish water than in freshwater culture.
Engineering Technology of White Shrimp (Litopenaeus vannamei) Intensive System Culture with the Suplementation of Phytase Enzyme in the Diet
Authors: Rachmawati Diana , Samidjan Istiyanto
Published: August 2020

This study aims to examine the effect of phytase enzyme in the diet on digestibility of growth of white shrimp (Litopenaeus vannamei) raised in intensive system culture. Research on the suplementation of phytase enzymes in L. vannamei diet is very important to hydrolyze phytic acid in vegetable ingredients as a source of diet protein so as to increase the efficiency of diet utilization to support growth of vaname shrimp. The shrimp used in the research had average weight of 1,19±0,06 g/shrimp.  The diet contained 38% of protein and 3200 Kcal DE/kg with various doses of phytase enzyme suplementation, namely: A (0 U/kg diet), B (500 U/kg diet), C (1000 U/kg diet) and D (1500 U/kg diet).  Observed parameters were digestibility of phosphore (ADCF), disgetibility of protein (ADCP), efficiency of diet utilitzation (EFU), protein efficiency ratio (PER), diet convesion ratio (FCR) relative growth rate (RGR), and survival rate (SR).  The suplementation of phytase enzyme in the diet significantly influenced (P<0.01) on ADCF, ADCP, EFU, PER, FCR, RGR; however, it did not significantly influence on SR of white shrimp.  The best treatment result was the suplementation of 1000 U/kg diet phytase enzyme (treatment C). The optimum dose of phytase enzyme in the diet was 867, 920, 923, 915, 1000 and 1000 U/kg of diet respectively for ADCF, ADCP, EFU, PER, FCR, RGR. Based on those result the suplementation of phytase enzyme can increase the growth of white shrimp.
Engineering Technology Fish Farming of Snakeheads Channa striat ,Bloch, 1793) Based Feed Vitamin C Increase to Superior Quality Using Microsatellite
Authors: Samidjan Istiyanto , Rachmawati Diana
Published: August 2020

Objectives for snakeheads farming Cngineered to produce superior products based artificial diet eenrichment vitamin C with different doses and the use of microsatellites to increase growth and determine the superior quality. Methods February to November 2017 Examined the Effect of artificial feed Enriched with vitamin C doses per 100 g feed were given 0 mg (T1), 12 mg (T2), 24 mg ,and 36 mg (T3), 48 mg (T4) were using a completely randomized design (CRD) and 4 treatments and 3 replications. Furthermore, to determine the superior quality using microsatellite genetic markers to see the genetic code snakeheads. Then the treatment was analyzed by ANOVA and data arrangement of molecular weight DNA, polymorphism were analyzed by Cco-stat and Minitab version 11. The data collected observations of the size of the  weight absolute, survival, FCR,  molecular weight DNA composition, heterogeneity genotype, polymorphism. The results showed that highest of polymorphism were T3 (weight absolute 169.18 mg) and lowest ppolymorphism  treatment T1 (weight absolute 149.25 mg) .Next analysis of polymorphism results using a micro-satellite in treatment (T2, ribbon 3,4), and (T3, ribbons 5.6) and (T4, ribbons 7 and 8)  respectively using IS-GB1F 5-CCC TGT ATT TCA TTT CTC CA-3 and IS-GB 1 R 5-ACC AAC ACT GCA ATC TCT CT-3 bright ribbons found in treatment T4 (ribbons 7.8) snakeheads are the results showed that the growth of snakeheads were highest in T3 (with ribbons 205bp allele ladder with 215 bps and 225 bps on the right, Addition as well as having polymorphism is high and. variation of different types also found the number of alleles and heterozygotes.
Plankton Diversity in Karst River, Masigit - Pawon Cave, West Java, Indonesia
Authors: Lewaru Muhammad Wahyudin , Pratiwi Fifi Dwi , Sunardi Sunardi
Published: August 2020

Karst Citatah region has been known strategies economic value of biotic and a biotic resources. This study investigated plankton biodiversity potency on Cibukur and Cibodas rivers where it already made in Karst Citatah region, particularly on Masigit-Pawon. The result of four stations showed that Karst Masigit-Pawon region was high potency with Plankton biodiversity resources with Diversity and dominancy index almost 1. The numbers of Plankton identified were of 24 species of phytoplankton consist of 9 class and 16 species of zooplankton consists of 6 filum. The high abundance of Plankton was Navicula sp(5.280 species), Synedra sp(4.092 species), dan Cyclops sp(2.904 species) respectively.
Quality Improvement of Catfish Floss (Clarias gariepinus) Through Oil Reduction Technology with Spinner and Press Tools
Authors: Romadhon Romadhon , Amalia Ulfah , Anggo Apri Dwi
Published: August 2020

The nutritional content of catfish allows this freshwater fish to be processed into a variety of products, one of which is fish floss. Fish floss is a product that is popular among the people so that many use it for sale and increase income. However, unfortunately many fish floss products that are of poor quality, for example, oil appeared in the packaging which consequently makes the fish floss products quickly rancid. The purpose of this study was to determine the optimal shelf life of floss catfish with the best quality. The experimental laboratories of this study was divided into three treatments: spinnered, pressed and combination of spinnered and pressed. The quality of fish floss were observed every 12 days for 48 days.The results showed that there were significantly effect of floss catfish with different treatments of oil reduction. The best quality of floss catfish was achieved at 36 days storaging, with an average value of water content 4.99%, 28.39% of protein content, 9.15% of fat content, 4.99 meq kg-1 of peroxide value and total plate count 6.9 x 10-3 cfu g-1.
Relationship of Distribution Seagrass Species with Dugong (Dugong dugon) Sighting at Liki Island-Papua
Authors: Nugraha Aditya Hikmat , Tasabaramo Ilham Antariksa , Hernawan Udhi E , Rahmawati Susi , Irawan Andri , Juraij Juraij , Khalifa Muta Ali , Dharmawan I Wayan Eka , Putra Risandi Dwirama , Puteri Devia Hartono
Published: August 2020

Dugong dugon is a herbivorous marine mammal. One of Dugong's favorite foods is seagrass. This study examines the distribution of seagrass species to dugong sighting in Liki Island. The study was conducted in November 2018. Observation of seagrass conditions was carried out using a line transect method and a 50x50 cm transect with a distance interval between 10 m plots. Interviews were also conducted with the community to find out the location of Dugong presence in Liki Island. There are seven species of seagrass found in Liki Island :Enhalus acoroides, Cymodocea rotundata, Thalassia hemprichii, Halophila ovalis, Halodule uninervis, Halodule pnifolia and Syringodium isoetifolium spread over four observation stations. The results showed that  Dugong in Liki Island is often found during the eastern season, they often appear in seagrass ecosystem area to do eating activities. Dugong is often found in the eastern part of Liki Island (Station 4) and sometimes also found in the western part of Liki Island (Station 3).Keywords:biodiversity,Dugong dugon, liki, papua, seagrass
Effect of Land Agricultural Fertilizer on Growth of Marine Single Cell Protein, Spirulina platensis, Chlorella vulgaris and Nannochloropsis
Authors: Sukardi Purnama , Wahyunika Ferisa , Winanto Tjahyo , Prayogo Norman Arie , Harisam Taufan , Mahdiana Arif , Marnani Sri
Published: August 2020

This study aimed to determine the growth rate and protein content in Nannochloropsis oculata, Chlorella vulgaris, Spirulina platensis were cultured using agricultural fertilizers. The agricultural fertilizers used were Urea, ZA and TSP. Each single cell protein was cultured using the three types of fertilizers with a ratio of Urea: ZA and TSP as follows (A) 1: 2: 1 [(10:20:10 g / L)], (B) 2: 2: 1 [(20:20:10 g / L)] and (C) 3: 2: 1 [(30:20:10 g / L)], respectively. The results showed that the best ratio of Urea, ZA and TSP fertilizers to growth of Spirulina, Nannochloropsis oculata and Chlorella vulgaris was C [30:20:10 (g / L)] treatment. However, phyto-protein content in Nannochlorophsis differed significantly between fertilization treatments, C fertilization yielded the highest protein content (28.75±0.05%), when compared with A (25.13±0.01%) and B (25.14±0.02%), respectively. In Chlorella vulgaris, all fertilization treatments showed very significant differences, B fertilization (28.24%±00.006) yielded the highest phyto-protein content, if compared to A (23.63% ± 0.003) and C (19.74% ±0.006 ), respectively. All fertilization treatments showed very significant differences (P <0.05) on Spirulina platensis. The highest content of phyto-protein (62.68 + 0.05%) was present in treatment C, when compared to A (52.18 + 0.05%) and B (62.37 + 0.01%) treatments, respectively.
Percepciones y actitudes sobre homofobia en estudiantes universitarios
Authors: Orcasita Linda Teresa , Vera Noriega José Ángel , Kusserow Magdalena , Montenegro Céspedes José Luis
Published: August 2020

Objetivo. Este artículo tiene como objetivo explorar las percepciones y actitudes sobre homofobia en estudiantes universitarios. Método. Desde una perspectiva cuantitativa, se contó con la participación de 228 jóvenes de una universidad privada de Cali-Colombia, la recolección de información se hizo a través de un cuestionario. El análisis estadístico de los resultados se realizó por las pruebas t-student y ANOVA. Resultados. Los resultados muestran diferencias significativas entre las variables género, facultad, ingresos y autoconcepto en las puntuaciones de homofobia. Los participantes masculinos, de ingeniería, con ingresos familiares altos y con un autoconcepto negativo, mostraron un nivel de homofobia más alto que el resto de los participantes. Conclusiones. Se concluye que los participantes relacionan la homosexualidad con ingresos familiares bajos, y que el autoconcepto positivo favorece la percepción y actitud hacia las personas homosexuales.
Evaluación de la Intervención Preventiva para Estudiantes Adolescentes en Riesgo (IPEA-R) en estudiantes de secundaria
Authors: Valadez-García Jorge Alberto , Oropeza-Tena Roberto
Published: August 2020

La adolescencia es considerada la etapa de mayor riesgo para iniciar el consumo de drogas, por lo que se hace necesario contar con intervenciones preventivas basadas en la evidencia que ayuden a evitar el uso de drogas en adolescentes. Objetivo. Evaluar la eficacia de La Intervención Preventiva para Estudiantes Adolescentes en Riesgo (IPEA-R) aplicada a una muestra de estudiantes de secundaria de México. Método. El estudio tuvo un diseño cuasi-experimental y participaron 60 estudiantes, 56.7% mujeres y 43.3% hombres, la edad promedio fue de 12.20 años (DE = .40). La intervención se compone de una sesión se evaluación, ocho de intervención y dos seguimientos. Se realizó un ANOVA Mixto para identificar diferencias entre los grupos experimental y control en las mediciones pretest, postest, primer seguimiento y segundo seguimiento. Resultados. Se encontraron diferencias estadísticamente significativas en las frecuencias del consumo de tabaco y bebidas alcohólicas, así como en la resistencia a la presión social, autocontrol, claridad emocional, reparación emocional, percepción del riesgo asociada al tabaco, y varias sustancias tóxicas. Conclusión. La IPEA-R es una intervención basada en la evidencia con efectos positivos tanto en la disminución de la fecuencia de consumo de diferentes sustancias tóxicas como en la mejora de habilidades personales de los adolescentes.
Theoretically designed interventions for colorectal cancer prevention: A Case of the Health Belief Model
Authors: Rakhshanderou Sakineh , Maghsoudloo Maryam , Safari-Moradabadi Ali , Ghaffari Mohtasham
Published: August 2020

Background: According to the WHO, most chronic diseases, including cancer, can be prevented by identifying their risk factors such as unhealthy diet, smoking and physical inactivity. This research examined the effectiveness of a theory-based educational intervention on colorectal cancer-related preventive nutritional behaviors among a sample of organizational staff. Methods: In this interventional study, 110 employees of Shahid Beheshti University of Medical Sciences were randomly divided into two groups (intervention and control) with cluster sampling. The data gathering tool was a researcher-made questionnaire containing two parts of 10-dimensional information and health belief model constructs. The educational intervention was conducted for one month and in four sessions in the form of classroom lecture, pamphlet, educational text messages via mobile phones and educational pamphlets through the office automation system. Two groups were evaluated in two stages, pre-test and post-test. Data were analyzed using SPSS-18 software, analysis of Covariance (ANCOVA) and independent t-test (intergroup comparisons). Results: Two groups were evaluated for variables such as age, sex, education level and family history of colorectal cancer, and there was no significant difference between the two groups (P < 0.05). After the two months since intervention, except for the mean score of perceived barriers, which was not significant after intervention, the mean scores of knowledge, perceived susceptibility, perceived severity, perceived benefits, perceived self-efficacy, behavioral intention, and preventive behaviors were significantly increased after the intervention in the intervention group compared to the control group (P > 0.05). Conclusion: Implementation of educational intervention based on health belief model was effective for the personnel, and can enhance the preventative nutritional behaviors related to colorectal cancer.
Metabolic syndrome in haemodialysis patients: Prevalence, determinants and association to cardiovascular outcomes
Authors: Delautre Arnaud , Chantrel François , Dimitrov Yves , Klein Alexandre , Imhoff Olivier , Muller Clotilde , Schauder Nicole , Hannedouche Thierry , Krummel Thierry
Published: August 2020

Background: In the general population, metabolic syndrome (MetS) is predictive of major adverse cardiovascular events (MACE). Waist circumference (WC), a component of the MetS criteria, is linked to visceral obesity, which in turn is associated with MACE. However, in haemodialysis (HD) patients, the association between MetS, WC and MACE is unclear.Methods: In a cross-sectional study of 1000 HD patients, we evaluated the prevalence and characterised the clinical predictors of MetS. The relationship between MetS and its components, alone or in combination, and MACE (coronary diseases, peripheral arteriopathy, stroke or cardiac failure), was studied using receiver operating characteristics (ROC) curves and logistic regression.Results: A total of 753 patients were included between October 2011 and April 2013. The prevalence of MetS was 68.5 %. Waist circumference (> 88 cm in women, 102 cm in men) was the best predictor of MetS (sensitivity 80.2; specificity 82.3; AUC 0.80; p < 0.05). In multivariate analysis, MetS was associated with MACE (OR: 1.85; 95CI 1.24-2.75; p < 0.01), but not WC alone. There was a stronger association between the combination of abdominal obesity, hypertriglyceridaemia and low high-density lipoprotein cholesterol with MACE after exclusion of impaired fasting glucose and hypertension.Conclusions: MetS is frequent and significantly associated with MACE in our haemodialysis cohort and probably in other European dialysis populations as well. In HD patients, a new simplified definition could be proposed in keeping with the concept of the "hypertriglyceridaemic waist".
Relationship of Breastfeeding Duration with Joint Pain and Knee Osteoarthritis in Middle-aged Korean Women: A Cross-sectional Study using the Korea National Health and Nutrition Examination Survey
Authors: Kim Min-Young , Kim Hyun-Joong , Noh Je-Heon , Kim Sun-A , Hwang Deok-Sang , Lee Chang-Hoon , Ha In-Hyuk
Published: August 2020

Background The effect of joint health on the quality of life of middle-aged and older women is becoming more widely recognized with the aging of the world’s population. However, the association of long-term breastfeeding with joint pain and knee osteoarthritis has not been fully examined. The aim of this study was to determine the association of prior breastfeeding duration with current joint pain and knee osteoarthritis in middle-aged Korean women. Methods This cross-sectional study was conducted among 3,454 women aged ≥50 years who underwent knee radiography and answered a questionnaire on breastfeeding and joint pain for the 5th Korea National Health and Nutrition Examination Survey (2010–2011). After adjusting for confounding sociodemographic, medical history, and obstetric and gynecologic variables, logistic regression analysis was conducted to analyze the prevalence of joint pain and knee osteoarthritis according to breastfeeding and its duration. Results Among the 3,454 participants, 298 had not breastfed and 1,042, 815, and 1,299 had breastfed for 1–24, 25–48, and ≥49 months, respectively. Of all participants, 1,731 had joint pain and 739 were diagnosed with knee osteoarthritis after radiography.The odds ratio (OR) for joint pain among women who breastfed was 1.49 (95% confidence interval [CI] 1.01-2.21). As the breastfeeding duration increased, the OR of joint pain prevalence also increased (p for trend; p=0.002). For knee osteoarthritis, the OR was 2.30 in the 25–48 months group (95% CI 1.09-4.86). The OR of knee osteoarthritis in the ≥49 months group was 2.17 (95% CI 1.01-4.64). Sensitivity analysis after selecting only participants aged ≥60 years showed that the prevalence of joint pain and knee osteoarthritis was more positively correlated with extended breastfeeding duration (joint pain, p for trend; p=0.005) (knee osteoarthritis, p for trend; p=0.012).Conclusions Long-term feeding for more than 25 months was associated with an increased prevalence of arthralgia and degenerative arthritis in Korean women aged ≥50 years.
A case series of children with adenovirus pneumonia: three-year experiences in a tertiary PICU
Authors: Shi Jingyi , Zhou Yiping , Wang Fei , Wang Chunxia , Miao Huijie , Sun Ting , Shan Yijun , Cui Yun , Zhang Yucai
Published: August 2020

Background: Describe the outcome of adenovirus pneumonia in a pediatric intensive care unit (PICU) over a 3-year period, to identify the risk factors that may be associated with worse outcome.Methods: A retrospective observational study was performed in the PICU of children’s hospital in Shanghai from July 2016 to June 2019. Sixty-seven children over 29 days to 14 years old with adenovirus pneumonia who were admitted to PICU with acute hypoxemic respiratory failure were included in this study. The primary outcome was hospital mortality, and secondary outcomes were hospital and PICU length of stay (LOS), and risk factors of worse outcome.Results: Of 67 children with severe adenovirus pneumonia, the hospital mortality was 16.42 % (11/67) and 28-day mortality was 14.93 % (10/67). Median Pediatric Risk of Mortality III (PRISM III) score at admission was 13 (interquartile range[IQR], 10-15). Median PICU LOS stay was 11days (8-18d) and hospital LOS was 22 days (16-31d). Among children with extracorporeal membrane oxygenation (n=9), 6 cases survived and 3 cases died. The patients who need renal replacement therapy, neuromuscular blockade, parenteral nutrition, and packed red blood cell perfusion had higher hospital mortality ( p = 0.000, p = 0.041, p = 0.000, p = 0.012, respectively). Multivariate logistic analysis indicated that liver dysfunction and nosocomial infection were associated with high risk of mortality.Conclusions: The hospital mortality of adenovirus pneumonia in our PICU was 16.42%. Patients complicated liver dysfunction and co-infection & nosocomial infection were associated with poor outcome.
Coal-bearing strata sequence stratigraphy of Paleogene Meihe Formation, Meihe Basin, NE China
Authors: Bai Yueyue , Lü Qingtian , Liu Zhaojun , Sun Pingchang , Liu Rong , Yao Shuqing
Published: August 2020

The Meihe Basin is an important Paleogene coal-bearing basin located in the Dunhua-Mishan Fault Zone, northeastern China. Based on a comprehensive study of well logs, seismic profiles, cores and rock geochemical properties, the coal distribution, paleoenvironment evolution within a sequence stratigraphic framework and the accumulation model to explain how coal seams developed in small fault basinsw were discussed in detail. Three third-order sequences were identified in the Paleogene Meihe Formation of Meihe Basin and the two coal-bearing sequences are the Lower Coal-bearing Member of Sequence I and the Upper Coal-bearing Member of Sequence III. All three types of system tracts are developed in both sequences, i.e., the lowstand systems tract (LST), the transgressive systems tract (TST), and the highstand systems tract (HST). In LST of Sequence I, fan delta plain marsh is the main coal accumulating environment where coal seams are thin, discontinuous and therefore uneconomic for mining, and it is the same with all coal seams developed in Sequence III. While in TST and HST of Sequence I, lake swamp is the main sedimentary environment where coal seams are thick, continuous, widely distributed, and thus economically attractive for mining. In the study area, the nice thick economical coal seams are usually developed in an ideal stable depositional environment where organic matter accommodation space grows at a balanced rate with peat, in other words, free of sediment input or channel migration. The key findings of this study could provide guidance for the exploration of coal seams in the Meihe Basin and other similar basins.
Efficacy of Orbital Radiotherapy in Moderate-to-Severe Active Graves’ Orbitopathy Including Long-lasting Disease
Authors: Choi Jin Hwa , Lee Jeong Kyu
Published: August 2020

Background: We aimed to explore the efficacy of orbital radiotherapy (RT) in patients with moderate-to-severe active Graves’ orbitopathy (GO), including long-lasting disease, and to determine the predictive factors associated with treatment response.Methods: This was a retrospective study of 62 moderate-to-severe active GO patients treated with RT. Demographic data and ophthalmic findings prior to RT and at 3 and 6 months afterward were analyzed. Computed tomography was performed before and after RT to compare orbital volume change. We used logistic regression to determine the predictive factors for treatment response. Subjects were divided into early- and late-active phase groups based on GO duration of 24 months and treatment outcomes were compared with each other to observe the effects of RT timing on treatment response. Results: Forty (64.5%) and forty-six (74.1%) patients experienced improvements in GO at 3 and 6 months after radiotherapy, respectively. Ocular parameters such as clinical activity score (CAS), proptosis, extraocular muscle (EOM) limitation, and compressive optic neuropathy (CON) were improved by RT. Volumes of EOM significantly decreased after RT. The enlargement of EOMs and EOM limitation were predictive factors for a good response to RT. At 6 months after RT, 22 (68.8%) patients of late-active phase group exhibited improvement in GO, which is comparable to the number of 24 (80.0%) patients of early-active phase group. In the late-active phase group, CAS, diplopia, and visual acuity were improved significantly, but there was no change in EOM limitation.Conclusions: In moderate-to-severe active GO patients, orbital RT may help improve high CAS, proptosis, EOM limitation, and CON. The orbital RT in long-lasting active GO patients may be considered as treatments for the relief of symptoms including high CAS and poor visual acuity.
Microenvironmental changes induced by placenta-derived mesenchymal stem cells restore ovarian function in ovariectomized rats via activation of the PI3K-FOXO3 pathway
Authors: Choi Jong Ho , Seok Jin , Lim Seung Mook , Kim Tae Hee , Kim Gi Jin
Published: August 2020

Background: Translational studies have explored the therapeutic potential and feasibility of mesenchymal stem cells (MSCs) in several degenerative diseases; however, mechanistic studies of the function of these cells have been insufficient. As ovarian failure causes anovulation as well as ovarian steroid hormonal imbalances, the specific aims of this study were to analyze the therapeutic role of placenta-derived MSCs (PD-MSCs) in an ovarian failure ovariectomy (OVX) rat model and evaluate whether PD-MSC transplantation (Tx) improved folliculogenesis and oocyte maturation in the injured ovary through PI3K/Akt and FOXO signaling.Methods: Blood and ovary tissue were collected and analyzed after various PD-MSC Tx treatments in an ovariectomized rat model. Changes in the expression of folliculogenesis- and ovary regeneration-related genes induced by PD-MSC treatments were analyzed by qRT-PCR, Western blotting, and histological analysis.Results: The levels of hormones related to ovary function were significantly increased in the PD-MSC Tx groups compared with those in the nontransplantation group (NTx). The follicle numbers in the ovarian tissues were increased along with increased expression of genes related to folliculogenesis in the PD-MSC Tx groups compared with NTx groups. Furthermore, Tx PD-MSCs induced follicle maturation by increasing the phosphorylation of GSK3 beta and FOXO3 (p<0.05) and shifting the balance of growth and apoptosis in oocytes.Conclusions: Taken together, these results show that PD-MSC Tx can restore ovarian function and induce ovarian folliculogenesis via the PI3K/Akt and FOXO signaling pathway.
Sensory gating and suppression of subjective peripheral sensations during voluntary muscle contraction
Authors: Takahara Terumasa , Yamaguchi Hidetaka , Seki Kazutoshi , Onodera Sho
Published: August 2020

Background: During voluntary muscle contraction, sensory information induced by electrostimulation of the nerves supplying the contracting muscle is inhibited and the somatosensory evoked potentials (SEPs) amplitude decreases. This depression of sensory input during voluntary muscle contraction has been demonstrated by many studies using electrophysiological methods. However, the association between the electrophysiological response of the sensory system during sustained muscle contraction and subjective peripheral sensation (SPS) is still unclear. The aim of this study was to investigate changes in spinal excitability, SEPs, and SPS during voluntary muscle contraction. Results: The appearance rate of the F-wave was significantly higher during muscle contraction than during rest, whereas no significant difference was observed in F-wave latency between muscle contraction and rest. Furthermore, the P25 amplitude of SEPs was significantly lower during muscle contraction than during rest, whereas the N20 amplitude of SEPs exhibited no significant differences. The SPS was significantly lower during muscle contraction than during rest. Conclusions: We conclude that sensory gating, which is found in the P25 component of SEPs during muscle contraction, is one of the neurophysiological mechanisms underlying the suppression of SPS.