bluuebunny/crossref_metadata_2025 huggingface dataset:
PRIVILEGIADOS DA PANDEMIA: HOME OFFICE EM TEMPOS DE COVID 19
Authors: Santos Ana Carolina de Souza dos , Fukuda Claudia Cristina
Published: September 2023

Este estudo de caso teve por objetivo compreender o impacto da pandemia no contexto do trabalho em home office, a partir das vivências dos trabalhadores de uma empresa e à luz dos conceitos de bem-estar no trabalho. A pesquisa foi realizada em duas etapas, uma quantitativa com o estudo de dados secundários e uma qualitativa por meio de entrevista com dezoito trabalhadores. Os resultados encontrados demonstraram que o processo de transição para o trabalho em home office demandou, em um primeiro momento, uma necessidade de adaptação ao trabalho e no ambiente com os familiares; e, necessidade de conciliar as demandas dos filhos, das atividades do lar e do trabalho. Os trabalhadores perceberam as ações da empresa, logo no início da pandemia, como tempestiva e cuidadosa; porém, essa percepção não se manteve ao longo do tempo. A transição para o home office impactou, ainda, no aumento do volume de trabalho, na quantidade de horas trabalhadas e reuniões. Constatou-se que a forma como a empresa lida com o processo de transição impactou o bem-estar de seus trabalhadores. Espera-se que este estudo possa auxiliar equipes gestoras de pessoas na construção ou reformulação de iniciativas que contribuam para o bem-estar dos trabalhadores.
Study on Structural Stability of ZrO2 and YSZ: Doping-Induced Phase Transitions and Fermi Level Shift
Authors: Nematov Dilshod , Burkhonzoda Amondulloi , Kholmurodov Kholmirzo , Lyubchyk Andriy , Lyubchyk Sergiy , Lyubchyk Svitlana
Published: September 2023

The article deals with the issues of structural stability, electronic properties and phonon dispersion of the cubic, tetragonal and monoclinic phase of ZrO2. The monoclinic phase of ZrO2 is found to be the most stable among all the phases of this compound, in terms of total energy comparison, the lowest enthalpy value, the highest entropy and the lowest negative modes found for m-ZrO2. An analysis of the electronic properties showed that during the m-t phase transformation of ZrO2, the Fermi level first shifts by 0.125 eV towards higher energies, and then, in the t-c section, goes down by 0.08 eV. In this case, the band gaps for c-ZrO2, t-ZrO2, and m-ZrO2 are 5.140 eV, 5.898 eV, and 5.288 eV, respectively. Calculations based on the analysis of the effect of doping with 3.23, 6.67, 10.35, and 16.15 mol. % Y2O3 on the m-ZrO2 structure showed that the m-YSZ enthalpy decreases linearly, which accompanies doped-induced phase transitions and further stabilization of monoclinic ZrO2. In this case, the position of the Fermi level changes stepwise, and the energy gap decreases. It has been found that not only for pure systems, including for Y2O3-doped systems, the p-states of electrons make the main contributions to the formation of the conduction band. The obtained results complement the database of research works carried out in the field of application of biocompatible zirconium dioxide crystals and ceramics for green energy generation and can be used in the design of humidity-to-electricity converters and the creation of solid oxide fuel cells based on ZrO2.
MicroRNA as Possible Mediators of the Synergistic Effect of Celecoxib and Glucosamine Sulfate in Human Osteoarthritic Chondrocyte Exposed to IL-1β
Authors: Cheleschi Sara , Veronese Nicola , Carta Serafino , Collodel Giulia , Bottaro Maria , Moretti Elena , Corsaro Roberta , Barbarino Marcella , Fioravanti Antonella
Published: September 2023

This study investigated the role of a pattern of microRNA (miRNA) as possible mediators of celecoxib and prescription-grade glucosamine sulfate (GS) effects in human osteoarthritis (OA) chondrocytes.
Chondrocytes were treated with celecoxib (1.85 µM) and GS (9 µM), alone or in combination, for 24 hrs, with or without interleukin (IL)-1β (10 ng/mL). Viability was detected by MTT assay, apoptosis and reactive oxygen species (ROS) by cytometry, nitric oxide (NO) by Griess method. Gene levels of miRNA, antioxidant enzymes, nuclear factor erythroid (NRF)2, and B-cell lym-phoma (BCL)2 expressions were analyzed by quantitative real time PCR. Protein expression of NRF2 and BCL2 was also detected at immunofluorescence and western blot.
Celecoxib and GS, alone or in combination, significantly increased viability, reduced apoptosis, ROS and NO production and the gene expression of miR-34a, -146a, -181a, -210, in comparison to baseline and to IL-1β. The transfection with miRNA specific inhibitors significantly counteracted the IL-1β activity and potentiated the properties of celecoxib and GS on viability, apoptosis and oxidant system, through NF-κB regulation. The observed effects were enhanced when the drugs were tested in combination.
Our data confirmed the synergistic anti-inﬂammatory and chondroprotective properties of celecoxib and GS, suggesting miRNA as possible mediators.
Establishing the Callus-Based Isolation of Extracellular Vesicles from Cissus Quadrangularis and Elucidating Their Role in Osteogenic Differentiation
Authors: Gupta Ritu , Gupta Sneha , Gupta Purva , Nüssler Andreas K , Kumar Ashok
Published: September 2023

Exosomes are membrane-bound, biologically active nanovesicles of size 30-200 nm produced by many cell types, such as both mammalian and plant cells. They are wrapped in a phospholipid bilayer and play a significant role in intercellular communications. The ease in their isolation and the ability of plant-derived exosome-like nanovesicles (PDEVs) to efficiently deliver bioactive constituents into mammalian cells have made them popular in contemporary research. PDEVs share many characteristics with mammalian EVs (MEVs), including shape, size, surface charge, and consist of bioactive molecules like lipids, proteins, nucleic acids, and tiny metabolites. However, the chemical composition profile of PDEVs and their biogenesis mechanism differ significantly from those of MEVs. They have been widely explored as potential therapeutic agents and are considered as good alternatives to act as a carrier for drug delivery. The present work elucidates the isolation of exosome-like-nanovesicles (henceforth exosomes) from the culture supernatants of an in vitro cultured callus tissue derived from a bone healing plant known for its osteogenic activity, i.e., Cissus quadrangularis. The physical and biological properties of exosomes were successfully studied using different characterization techniques. To assess their therapeutic potential, we studied the internalisation of calcein-AM labeled exosomes by human derived mesenchymal stromal cells (hMSCs). Additionally, we evaluated the potential of exosomes in the migration of cells in a cell scratch assay with hMSCs and their effect on amelioration of oxidative stress was investigated on preosteoblast MC3T3-E1 cells that were pre-treated with these exosomes. Furthermore, we investigated their proliferation and differentiation to osteoblasts like cells with the help of resazurin assay and alkaline phosphatase assay (ALP). The obtained results provide a primary justification for the use of Cissus quadrangularis-derived exosomes as a nanocarrier for drug molecules for various therapeutic bone applications.
The Intersection of Health Literacy and Public Health: A Machine Learning-Enhanced Bibliometric Investigation
Authors: Tabak Benjamin Miranda , Froner Matheus Britto , Corrêa Rafael , Silva Thiago Christiano
Published: September 2023

Introduction: In recent decades, health literacy, in connection with a broad range of public 1 health terms, has become a burgeoning field. This study aims to explore trends and biases in this 2 area through a bibliometric analysis. Methods: A Random Forest Model was utilized to identify 3 keywords and other metadata that predict annual citations in the field. In order to supplement 4 this machine learning analysis, we have also implemented a bibliometric review of the corpus. 5 Results: Findings indicate a high positive coefficient for the keyword ’Covid-19’ and ’Male’, whereas a 6 negative coefficient was observed for ’Female’, suggesting potential biases. Evolving themes such as 7 Covid-19, Mental Health, and Social Media were discovered. A significant shift was noted in the main 8 publishing journals, while the major contributing authors remained the same. Discussion: The results 9 hint at the influence of the Covid-19 pandemic and potential gender biases on citation likelihood, as 10 well as changing publication strategies despite the fact that the main researchers remain as the ones 11 that have been studying health literacy since its creation.
First-principles study of adsorption of Pb atoms on 3C-SiC
Authors: Komorowicz Michal , Skrobas Kazimierz , Czerski Konrad
Published: September 2023

Changes in the atomic and electronic structure of silicon carbide 3C-SiC (β-SiC), resulting from lead adsorption, have been studied within the density functional theory. The tests were conducted for three representative surfaces with varying degrees of lead coverage. Results indicate that chemisorption occurs, with the strongest binding, found on the hexagonal surface (111) in interaction with three dangling bonds. The adsorption energy rises with increasing coverage, especially as the surface approaches saturation. Analysis of the data was focused on parameters important for corrosion processes such as bond distances, binding energies, Bader charges and charge density difference.
Ceramides Mediate Insulin-Induced Impairments in Cerebral Mitochondrial Bioenergetics in ApoE4 Mice
Authors: Carr Sheryl T. , Saito Erin R. , Walton Chase M. , Saito Jeremy Y. , Hanegan Cameron M. , Warren Cali E. , Trumbull Annie M. , Bikman Benjamin T.
Published: September 2023

Alzheimer’s disease (AD) is the most common form of neurodegenerative disease worldwide. A large body of work implicates insulin resistance in the development and progression of AD such that AD may be a form of brain insulin resistance. Moreover, impairment in mitochondrial function, a common symptom of insulin resistance, now represents a fundamental aspect of AD pathobiology. Ceramides are a class of bioactive sphingolipids that have been hypothesized to drive insulin resistance. Here we describe preliminary work that tests the hypothesis that hyperinsulinemia pathologically alters cerebral mitochondrial function in AD mice via accrual of the ceramides. Homozygous male and female ApoE4 mice were given chronic injections of PBS (control), insulin, myriocin (an inhibitor of ceramide biosynthesis), or insulin and myriocin over four weeks. Cerebral ceramide content was assessed using liquid chromatography-mass spectrometry. Mitochondrial oxygen consumption rates were measured with high-resolution respirometry, and H2O2 emissions were quantified via biochemical assays on brain tissue from the cerebral cortex. Significant increases in brain ceramides and impairments in brain oxygen consumption were observed in the insulin-treated group. These hyperinsulinemia-induced impairments in mitochondrial function were reversed with the administration of myriocin. Altogether, these data demonstrate a causative role for insulin in promoting brain ceramide accrual and subsequent mitochondrial impairments that may be involved in AD expression and progression.
Theoretical Study of Measuring Moving MEGs with 83Kr Based Atomic Co-Magnetometer
Authors: Chen Yao , Guo Ruyang , Wang Jiyang , Yu Mingzhi , Zhao Man , Zhao Libo
Published: September 2023

K-Rb-83Kr based atomic co-magnetometer for measuring moving MEGs is theoretically studied in this paper. Parameters such as the spin exchange rates, the spin dephasing rates and the polarization of the nuclear spins are studied to configure the co-magnetometer. Results show that the nuclear spin could generate around 700 nT magnetic field under which the nuclear spin could compensate wide range of magnetic fields. We also showed the hybrid optical pumping vapor cell fabrication process in this paper. Alkali metals were mixed in a glove box and then was connected to the alkali vapor cell fabrication system. The vapor cell fabrication process is illustrated in this paper.
On the Order Estimate of the Mertens Function and its Relation to the Zeros of the Riemann Zeta Function
Authors: De Subham
Published: September 2023

The primary purpose of this article is to deduce specific order estimates for the \textit{Mertens Function} $M(n)$, which facilitates us to analyze the location of zeros of the \textit{Riemann Zeta function} $\zeta(s)$. The paper also provides a brief overview about the notion of the \textit{Mertens Function} $M(n)$ and \textit{Redheffer Matrices} $\mathbb{A}_{n}$. In addition to learning about various \textit{spectral properties} of $ \mathbb{A}_{n}$, we shall also deduce the relation between these two, which, eventually would lead us to establish a necessary and sufficient condition for the \textit{Riemann Hypothesis} to hold true, as justified by \textit{Redheffer} himself. We shall also observe several numerical evidence as well as theoretical justification behind the falsity of the famous \textit{Mertens Hypothesis}, along with how researchers over the years have approached towards deriving an estimate of the smallest possible natural number $n$ for which the first such violation of the theorem occurs, utilizing numerous conjectures annotating about the order of $M(n)$. Readers who are highly motivated in pursuing research in any of the topics relevent to the contents of this paper will surely find the \texttt{References} section to be extremely resourceful.
An Update on Biogeography of Decapod Crustaceans from a Collection of Soft‐Bottom Macrofauna of the Central Mediterranean Sea
Authors: Bacci Tiziano , Targusi Monica , Lattanzi Loretta , Marusso Veronica , Trabucco Benedetta , Tomassetti Paolo
Published: September 2023

Decapod crustaceans are important components of the fauna of soft bottom habitats. In this work, biogeographical updates of decapod crustaceans are provided through the analysis of a large soft bottom benthic macroinvertebrates data set of the central Mediterranean Sea. Decapod crustacean assemblages were collected in the last twenty years by a Van Veen grab on 42 study sites located along the Italian coasts at depths ranging from the surface up to 120 meters. Spatial distribution of the crustaceans examined, which include 123 species belonging to 40 families, has been investi-gated according to the biogeographical zones identified in the Italian Seas. Spatial distribution of 39 species has been updating, comparing the ISPRA decapod crustacean dataset with the most recent Italian checklists. For the species updated, number of specimens and environmental data, such as bathymetric range and habitat details, are provided for each site investigated. Data are discussed and compared with the existing literature, also referring to what is reported in the World Register of Marine Species (WoRMS), with the aims to contribute to the knowledge of biodiversity of the marine species provide useful data to assist the insiders to update checklists and registers at national and global scale and information on species ecology.
Aspects of Urban Climate Adaptation and Mitigation Plans: The Bologna Case Study and Outcomes
Authors: Cremonini Letizia , Georgiadis Teodoro , Nardino Marianna , Rossi Federica , Rossi Alessandro , Pinca Giovanna , Fazzini Massimiliano
Published: September 2023

The public administrations (PAs) that have joined the Covenant of Mayors must now complete their adaptation plans with the climate chapter (SECAP). At the same time, the previous Plan for sustainable energy (SEAP) was mainly dedicated to mitigation actions (sustainable energy). It was often managed directly by municipalities' in-house energy companies or agencies. The WMO1234 Recommendation (Guidance on Integrated Urban Hydrometeorological, Climate and Environmental Services) is a fundamental Guidance to allow PAs to make policies and decisions regarding city regeneration and population health prevention. The purpose of this manuscript is to describe a process undertaken in the Emilia-Romagna region to build a coherent frame from the individuation of local environmental vulnerabilities and adopt specific policies. This frame was created by the contribution of various Institutions, including the Regional Authority, which furnished the main directives and tools for the mitigation and adaptation, the Municipality of Bologna, which prepared the first Adaptation Plan following the SECAP guidance, the Emilia-Romagna branch of Italian Association of Municipalities (ANCI), which took in charge the approach to harmonize different urban contexts and to communicate with stakeholders and population, and Research Institutes and Scientific Associations to explore, with specific studies and modeling application, the outcomes produced by a joint support to the new urban directives, such as the General Urban Planning Plan (PUG). To achieve this result, the WMO Guidance 1234 has been assumed as a reference methodology to ensure the best utilization of available data and widespread a common science-based methodological approach to other municipalities.
CYP2C19 Pharmacogenetics and Clopidogrel Prescription in a University Hospital: A Descriptive Study in a Clinical Data Warehouse
Authors: Maes Alexandre , Gosselin Laura , Triquenot Aude , Darmoni Stéfan , Grosjean Julien , Lamoureux Fabien , Wils Julien
Published: September 2023

Clopidogrel is one of the most prescribed antiplatelet drugs for cardiovascular diseases prevention. Clopidogrel is a prodrug metabolised by CYP2C19 in active metabolites with anti-aggregant effect. Pharmacogenetic variants such as CYP2C19*2 variant can alter the anti-aggregant effect of clopidogrel leading to a higher risk of cardiovascular disease relapse. The aim of this study was to evaluate the prescription characteristics of CYP2C19 pharmacogenetics in patients on clopidogrel treatment, based on a specific query in a clinical data warehouse. We evaluated the demographics of patients, prescribers, medical indications, CYP2C19 pharmacogenetic tests and therapeutic changes. Neurologists were the main prescribers of CYP2C19 pharmacogenetic tests associated with clopidogrel treatment in a context of suspicion of stroke relapse. Pharmacogenetic tests were mainly prescribed a posteriori to clopidogrel prescription. Clopidogrel pharmacogenetic resistance was associated with the prescription of lysine acetylsalicylate in substitution of clopidogrel. Clear clinical practice guidelines are needed to position CYP2C19 pharmacogenetic testing for patients on clopidogrel treatment.
A Network Comprised of miR-15b and miR-29a is Involved in VEGFA Pathway Regulation in Thymus Adipose Tissue from Elderly Ischemic Cardiomyopathy Subjects
Authors: Gentile Adriana-Mariel , Lhamyani Said , Mengual Mesa Maria , Pavón-Morón Francisco Javier , Pearson John R , Salas Julian , Clemente-Postigo Mercedes , Perez Costillas Lucia , Olveira Gabriel , El Bekay Rajaa
Published: September 2023

Adult human thymus degenerates into adipose tissue (TAT). In contrast to subcutaneous adipose tissue (SAT), TAT has been reported to exhibit enhanced angiogenic properties in elderly people. We have previously shown that vascular endothelial growth factor A (VEGFA) is the most abundant angiogenic growth factor in TAT of patients with ischemic cardiomyopathy (IC), and that VEGFA levels are increased in elderly (>70 years) compared with middle-aged patients. This makes TAT a promising candidate for angiogenic therapies and the regeneration of ischemic tissues following coronary surgery. MicroRNAs (miRNAs) have emerged as attractive therapeutic targets, especially those that regulate angiogenic processes. The study's purpose is to determine the miRNA network associated with both VEGFA pathway regulation and enrichment of age-linked angiogenesis in the TAT.
Debris Flow Prediction in Mountainous Terrain Using Remote Sensing and GIS: A Case Study of Al-Hada Road, Makkah Province, Saudi Arabia
Authors: Alharbi Talal , El-Sorogy Abdelbaset S.
Published: September 2023

In Saudi Arabia’s mountainous regions, debris flow is a natural hazard that poses a threat to infrastructure and human lives. To assess the potential zones of debris flow in the Al-Hada Road area, a study was conducted using Geographic Information System (GIS) analysis and remote sensing (RS) data. The study took into account various factors that could affect debris flow, such as drainage density, elevation, slope, precipitation, land use, geology, soil, and aspect. The study also included a field trip to identify 11 previous debris flow events that were influenced by high-density drainage and slope. The study utilized weighted overlay analysis in a GIS environment to create a map indicating the potential debris flow zones in the area. According to the analysis, low-risk areas cover 35,354,062.5 square meters, medium-risk areas cover 60,646,250 square meters, and high-risk zones cover an area of 8,633,281 square meters. This result was verified using the locations of previous debris flow events. The study’s findings can help planners and decision-makers identify and prioritize areas for mitigation and prevention measures. Additionally, the study contributes to understanding debris flow hazards in arid and semi-arid regions.
A Descriptive Review of Medication Overuse HEADACHE-from Pathophysiology to the Clinic
Authors: Ljubisavljevic Srdjan , Damjanovic Radomir , Ljubisavljevic Marina , Kalinic Sreten
Published: September 2023

Purpose of review: Medication overuse headache (MOH) is an important problem worlwide areas of different controversy regarding its entity. This article reviews the risk factors, comorbidities, pathophysiology, clinical presentation, effective management and prognosis of MOH, by summaries and integrates the results and finding in previously performed more than 15000 studies (from the year of 2010 to 2023) available from the scientific database of the University Medical Library in the University Clinical centre of Niš, which aimed to investigate and define a complexcity of this type of headache. Recent finding: It has been proposed that all acute migraine medications can lead to MOH, with differences in the propensity of different agents to cause the problem. Early data suggests that triptans and other pain killers used for the acute treatment of migraine, may be an exception. Recent studies show that practicioners and the general public are still largely unaware of the problem of medication overuse and its damaging effects. Summary: Although it is likely that MOH does occur and restricting the amount of acute medications is necessary to prevent it. It is also possible that increasing amounts of acute medications are simply a reflection of poorly controlled headaches, rather than a couse. Further researches need to be developed to identify more precisious mechanism in MOH effecitive management and its evolution. Key word: medication overuse headache (MOH)
Human–Robot Collaboration: Understanding the Effects of Different Levels of Automation Assistance on Enhancing Eye-Gaze-Based Mobile Robot Tele-operation
Authors: Quan Zikun , Fatah gen. Schieck Ava , Elashry Khaled
Published: September 2023

The introduction of autonomous technologies in cities—such as driverless cars, ground robots, and drones—promises to transform urban services and interactions. As a newly emergent, intuitive, and promising technology, eye-gaze-based mobile robot teleoperation (referred to as Tele-gaze in this context) has recently been applied to human–mobile robot interaction for various activities in cities, such as in the use of assistive technologies to improve the autonomy and well-being of people with limited mobility. More recently, we have begun to witness a shift that takes advantage of automation assistance to improve human performance using Tele-gaze. However, there is a knowledge gap with regard to how various levels of automation assistance, when combined with interaction modalities, can affect human operators and their collaboration with non-human agents. More specifically, we need to identify the factors that can influence the Tele-gaze-based systems and their effects on the human–robot collaboration. In this paper, a novel Tele-gaze system supported by four interactive modalities is proposed. The eye-gaze control is supported by increasing levels of automation assistance from the mobile robot side, with two basic mechanisms (eye-imitation camera and user-will trigger mechanisms) present in all four modalities—Modality 1: without any automation assistance; Modality 2: with a collision-avoidance mechanism; Modality 3: with a collision-avoidance mechanism and pathway middle mechanism; and Modality 4: with a collision-avoidance mechanism and a guideline-following mechanism. Four sets of experiments with an indoor navigation task were conducted with the four interactive modalities. Each set was tested by our 12 participants using one of the four modalities. We analyzed and discussed the experiments’ outcomes from both (1) the mobile robot side and (2) the human operator side. Early findings indicated that automation assistance and human capacity can not only reinforce one another but also constrain one another. We suggest that adopting the right balance, with the appropriate level of automation assistance, is key to enhancing the Tele-gaze-based interactions without compromising human dominance, user experience, and the flexibility of the system capacity.
Twenty-month Monitoring of Humoral Immune Response to BNT162b2 Vaccine: Antibody Kinetics, Breakthrough Infections and Adverse Effects
Authors: Walory Jaroslaw , Ksiazek Iza , Karynski Michal , Baraniak Anna
Published: September 2023

Background: Vaccination is one of the most effective life-saving medical interventions, and the introduction of SARS-CoV-2 vaccines was intended to prevent the serious implications of COVID-19. The objectives of the study were: i) to observe the humoral immune response to BNT162b2 vaccine and SARS-CoV-2 infection (mainly breakthrough infections), ii) to demonstrate the persistence of anti-SARS-CoV-2 antibodies over time in relation to the number of received vaccine doses and the course of infection, and iii) to determine adverse effects after primary vaccine doses. Methods: To assess the humoral response, IgG and IgA anti-S1 antibodies were quantified by ELISA assays. In total, the tests were carried out seven times in almost two years. Results: We demonstrated strong immunogenicity (compared to levels before primary vaccination, 150- and 20-fold increases in IgG and IgA, respectively) of the BNT162b2 vaccine. Over time, we observed a systematic decline in antibody levels, which may have contributed to breakthrough infections. Although they caused seroconversion similar to the booster, antibody levels in such patients fell more rapidly than after re-vaccination. On the other hand, in individuals who did not receive booster(s) and who did not present breakthrough infection, anti-SARS-CoV-2 antibodies returned to pre-vaccination levels after 20 months. The most commonly recognized adverse effects were injection site redness and swelling. Conclusion: Vaccination is highly effective in preventing the most severe outcomes of COVID-19 and should be performed regardless of prior infection. Booster doses significantly enhance anti-SARS-CoV-2 antibody levels and, in contrast to those obtained by breakthrough infection, they remain longer.
Asymmetric Orthogonal Metasurfaces Governed by Toroidal Dipole Bound States in the Continuum
Authors: Ji Jun , Lv Xiaolong , Yang Xiaoyuan , Guo Yunsheng
Published: September 2023

An all-dielectric metasurface composed of orthogonal-slit silicon disks is proposed in this study. By modifying the unit structure of the metasurface with the bound states in the continuum (BIC) theory, a sharp Fano resonance can be generated. The resonance properties of the metasurface are investigated by analyzing the effects of the structural parameters on the resonance using the eigenmode analysis method. The Q factor and the resonance wavelength can be adjusted by varying the slit width, the disk thickness, and the disk radius. The electromagnetic characteristics and mechanism of the toroidal dipole-BIC (TD-BIC) are explored in depth through an analysis of the multipole expansion of the scattered power, along with the electromagnetic field and the current distribution at resonance. This research provides a novel approach for excitation of a strong TD-BIC resonance and proposes potential applications in optical switches, high-sensitivity optical sensors, and related areas.
Effect of Leaflets and Balanced Menu Videos on Knowledge, Attitudes and Behaviors among Undernourished Toddlers’ Mothers
Authors: Maftuchah Maftuchah , Setyaningsih Faridha , Nurhayati Susi
Published: September 2023

Background: Toddlers are a vulnerable group in terms of nutrition and are at a high risk for disease. Toddlers’ nutritional health might be affected by a lack of nutrient intake. The nutritional status of children under the age of five is critical since it is an indicator of their health and nutritional status. Malnutrition continues to increase in Sukodono where there are currently 54 undernourished toddlers. This is due to the mother’s lack of knowledge. Counseling through leaflets and video screenings is one of the media for increasing mothers’ knowledge. This study aimed to analyzed the effect of leaflets and balanced menu videos on the knowledge, attitudes and behavior of malnourished mothers under five in the village of Sukodono Tahunan Jepara, Central Java.

Methods: A quantitative research with quasi-experimental approach. The populations of the study were 54 undernourished toddlers at the aged 1 to 5 years. A total of 32 undernourished toddlers’ mothers in Sukodono were included in this study, and divided into 16 subjects from control group (using leaflet) and 16 subjects from intervention group (using video).

Results: There was an effect of balanced menu leaflet media on the knowledge, attitudes, and behavior of malnourished toddler mothers in the village of Sukodono Tahunan Jepara. There is an effect of balanced menu video media on the knowledge, attitudes, and behavior of malnourished toddler mothers in Sukodono Tahunan village, Jepara. There is no more effective difference between giving leaflets and balanced menu videos on the knowledge, attitudes, and behavior of malnourished toddler mothers in Sukodono Tahunan Jepara village with p values > 0.05 (0.434, 0.067 and 0.131).

Conclusion: There is no more effective difference between the provision of leaflets and balanced menu videos on the knowledge, attitudes, and behavior of undernourished toddlers’ mothers in Sukodono Tahunan Jepara with a p value > 0.05 (0.434, 0.067 and 0.131.

 
ASSOCIATION BETWEEN EXISTENCE SIBLING AND PRAGMATIC ABILITY AMONG PRESCHOOL CHILDREN: PATH ANALYSIS EVIDENCE FROM SURAKARTA
Authors: Susanti Nadya , Putri Anggi Resina
Published: September 2023

Background: In each phase of development, children do not only grow physically, but also from a psychological to intellectual point of view. Children who don't get enough stimulation may show signs of developmental problems in their language and speech. The presence of siblings can affect the development of personality and the ability to communicate with children. Children who have existence siblings get more language and speech stimulation from their parents and siblings.

Methods: This study used a cross sectional study design, which was conducted in Surakarta City. A sample of 200 people was selected using a random sampling technique. Data collection was performed using a questionnaire and analyzed by path analysis.

Results: There was a direct relationship between children with siblings having a log odds of good pragmatic skill 4.97 units higher than children without siblings (b=4.97; 95% CI= 3.70 to 6.24; p= <0.001). Positive parenting styles had a log odds of experiencing good pragmatic skill of 3.42 units higher than children with negative parenting styles (b=3.42; 95% CI= 2.10 to 4.69; p= <0.001). Children who have existence siblings are indirectly related to pragmatic skill through parenting style. Children with existence siblings had the possibility of having good pragmatics skill by 1.73 units higher than children without siblings (b=1.73; 95% CI= 1.07 to 2.3; p= <0.001).

Conclusion: Good pragmatic skill was directly influenced by the existence sibling and positive parenting style. Pragmatic abilities are indirectly related to existence sibling through positive parenting style.
The Incorporation of 4C Skills in Senior High School English Teachers’ Lesson Plans
Authors: Radifan Muhammad Fadil , Dewanti Ratna
Published: September 2023

This study aims at describing how the 4C skills are incorporated in senior high school English teachers’ lesson plans and investigating the lesson plan components in which those skills are incorporated. The data for this qualitative study were collected through content analyses on ten lesson plans by three senior high school teachers in Jakarta. The study found that all lesson plans that were analyzed have incorporated all of the four 4C skills, which consist of creativity and innovation, critical thinking and problem solving, communication, and collaboration. Among all indicators of the 4C skills’ incorporation, some were found to be incorporated in all lesson plans regardless of their topics, while others were more dominantly incorporated in lesson plans that discuss certain topic categories. The findings of the study also showed that most 4C skills were incorporated in the same four categories of lesson plan components: learning steps, assessment, learning methods, and indicators of competence achievement. An exception to this is the collaboration skill, which was not incorporated in components involving indicators of competence achievement. These findings are expected to aid teachers in specifying 4C skill aspects to incorporate in their lesson plans and the components to incorporate those aspects into.
The Rhetorical Functions of Citations in the Discussion Sections of Two Articles in Journal of English for Academic Purposes
Authors: Karamina Putri , Wachidah Siti
Published: September 2023

This study aims to examine the transitivity system of rhetorical functions in the Discussion section of two articles in the Journal of English for Academic Purposes by investigating the type of processes used in the rhetorical functions and how each type of process is represented in the English lexicogrammatical system. The data for this qualitative study were collected through genre analysis on two articles on citation practices from the Journal of English for Academic Purposes. The study found that comparison with sources and attribution were the most prominent rhetorical function within the Discussion section and that in comparison with sources, verbal processes were the most dominant type of processes, followed by relational, material, and mental processes, while in attribution, relational processes were the most used type of process, with material, verbal, and mental processes following behind. The findings of the study also showed that both comparison with sources and attribution were equally important in the Discussion section.
Type of Collaborative Learning of Kagan Framework in Microteaching Course of ELESP UNJ
Authors: Tanzilla Rafiqa , Tamela Ellis
Published: September 2023

This study aims to identify what collaborative learning is in the microteaching class of the English Language Education Study Program, Jakarta State University. Indicators in collaborative learning are based on research and statements from Kagan (2015). In conducting this research, data were collected from the student-student teacher activities and interactions in microteaching class activities. The finding showed that type of collaborative learning in this course belonged to learning together. The activities in learning together were when the student teacher decided on group size, assign students to groups, arrange the room, assign roles, explain the academic task, monitor student's behavior, provide task assistance, and provide closure. The results of the study hopefully can give insights on how to conduct collaborative learning an any subjects or courses.
Digital Comic Strips as Multi-Modal Text for Learning Interpersonal and Transactional Text in Junior High School: A Content Analysis
Authors: Pratiwi Anisa , Palupi Tara Mustikaning
Published: September 2023

This research aimed to analyze the content of the digital comic strips for learning interpersonal and transactional text at Junior High School levels. The research was conducted based on the research questions: (1) How is the suitability of the digital comic strips used for grade 8 Junior High School in terms of the content of the interpersonal and transactional text? (2) How do the digital comic strips meet the criteria of digital learning material? The research used qualitative content analysis the instrument of which was adapted from the Indonesia Minister of Education and Culture Indonesia Syllabus and three Digital Learning Material Framework. The data was sourced from the digital comic strips uploaded on social media and comic strips web. It was revealed that 95% of all of the digital comic strips already have the language features that the Indonesia Education and Culture Minister stated on the syllabus, also accomplish the digital material learning criteria from accessibility and content by The National Center for Accessible Educational Resources (AEM), PRIMO (Peer-Reviewed Instructional Materials Online) Selection Criteria, and Petri Nokelainen. The findings revealed promising future to use digital comic strips as an instructional reading materials.
Discourse Analysis of a News Text Using Cohesion and Ethnography of Speaking Theories
Authors: Angela Audreylia Sabrina  , Gunawan Salsabilla Maharani Mutiara , Pujiati Hanip
Published: September 2023

The purpose of this study was to undertake a thorough study of a news article entitled "31 Policemen Questioned in Kanjuruhan Stadium Tragedy" by looking at both its contextual and textual elements. To analyze the data, the research used a content analysis and discourse analysis design. While the contextual study relied on Dell Hymes' ethnography of communication, notably the Speaking Model (Hymes, 1974), the textual analysis concentrated on the coherence devices given by Halliday and Hasan (1976). All essential elements, such as the setting, participants, ends, act order, key, instruments, and norms, were identified, according to the contextual analysis. The four content categories of reference, substitution, ellipsis, and conjunction were found in the textual analysis; however, the article did not fully contain all sub-categories.
DA FAZENDA BARREIRINHA À UNIVERSIDADE FEDERAL DO AMAZONAS
Authors: Marinho Rogério Ribeiro , Silveira de Queiroz Matheus
Published: September 2023

Nesta entrevista, exploramos a notável carreira do Professor Dr. José Alberto Lima de Carvalho, destacando seu percurso desde a infância nas margens do Rio Urubu (Itacoatiara-AM) até sua destacada trajetória como professor do Departamento de Geografia na Universidade Federal do Amazonas. Sua história é um testemunho de resiliência, determinação e dedicação à educação na Amazônia, resultando em uma carreira acadêmica exemplar com contribuições significativas para o pensamento complexo e a geografia física da Amazônia ribeirinha
Sustainable Restoration of Degraded Landscapes Improves Soil Glomalin Content
Authors: Yelikbayev Bakhytzhan , Correa Eduardo , Duarte Neimar , Pagano Marcela
Published: September 2023

The rising use of plantations forwood and cropping systems for food, the agronomic pressures, and resource overexploitation, in addition to climate change constrains, need urgent efforts for restoration of the different vegetal covers. Thus, research in ecosystem restoration is rising worldwide as the perception that global change negatively affects ecosystem services as well as the above and belowground biodiversity. Among microorganisms, mycorrhizae and Rhizobia benefit and contribute to the natural regeneration of plant communities. Consequently, the study of mycorrhizas in natural ecosystems supplement with relevant information the restoration plans. The understanding that most plants are mycotrophic influences the rehabilitation efforts of varied vegetation types. We show here the ecosystem restoration with respect to the benefits of plant symbiosis. As an index of soil stabilization in the different sites glomalin content (Undisturbed= Restored > Disturbed), was the best predictor of restoration success.
Evaluation of a combined index based on hydrological model for drought monitoring in central Iran
Authors: Niazi Yaghoub , Talebi Ali , Hassan Marwan A.
Published: September 2023

In recent years, drought has become a global problem. Undoubtedly, drought monitoring is an important step for combating and reducing the resultant damage. In this study, the components of water and energy balance in the Central Iran region were simulated using the VIC land surface model. The output components of this model, especially soil moisture after evaluation, were used as inputs in the drought index based on Palmer's water balance. The integrated index of the VIC-PDSI in comparison with conventional Palmer indices and the SPI index at the 3, 6, 12, 24, and 48-month intervals was fitted with increments in moisture data and variations in the storage of water extracted from GRACE satellite data. Results showed that the combination of VIC-PDSI had the highest correlation coefficient of 0.87 with groundwater level change compared with other drought indices.
The impact of public leadership on collaborative administration and public health delivery
Authors: din Muhammad Zia ud , yuan Xu Yuan , khan Naqib ullah
Published: September 2023

Background:This research depicts the linkage of public leadership on public health delivery (PHD) and collaborative administration. The research is also focused to examine the effect of public leadership on public health delivery through the intervening variable of collaborative administration by using both social information processing theory and collaboration theory.Methods:This research is based on quantitative method. Data was collected from 464 public hospital administration in the context of Pakistan. This study evaluated data using SPSS, AMOS and PROCESS Macro.Results:Public leadership has a positive profound effect on public health delivery and collaborative administration, and that collaborative administration significantly promotes public health delivery. The outcomes also exposed that public leadership has substantial influence on public health delivery through intervening collaborative administration.Conclusions:Whilst public leadership demonstrated positive outcomes on public health delivery and collaborative administration, there is a need for more rigor studies on collaborative governance leadership, collaborative ethics and collaborative norms in the public health service.
Poria acid alleviates oxidative damage in mice with dry age-related macular degeneration by activating the Nrf2/HO-1 signaling pathway
Authors: Qin Chengyao , Chen Xi , Hu Tianming , Sun Wenxiu , Liu Zehao , Li Min , Wei Wei , Shao Yan
Published: September 2023

Background
Poria acid (PA) extracted from the traditional Chinese medicinal herb Poria cocos (P cocos) is reported to protect organs such as the liver and lungs from damage. However, its effect on dry age-related macular degeneration (AMD) has not been reported. This research is to investigate the influence of PA on oxidative stress of the retina in vivo and in vitro.
Methods
In vitro, the viability of ARPE-19 cells was measured by the MTT. The apoptosis of the cells was detected by Flow cytometry and the expression of Caspase-3, Bax, and Bcl2. The oxidative stress level was evaluated by observing the production of reactive oxygen species (ROS) in vitro and superoxide dismutase (SOD), CAT, and GSH-px by ELISA in mice serum. The AMD model was induced by intravenous injection of sodium iodide (SI) through the tail vein of mice. The structure and the apoptosis of the mouse retina were monitored by optical coherence tomography (OCT), H&E, and TUNEL staining. The regulatory oxidative factor NRF2 and HO-1 were determined by fluorescence staining. ML385 and ZnPP were used for the exploration of the protective mechanism of PA.
Results
H2O2 decreased the cell viability of RPE cells, and was recovered after PA administration, which was shown to reduce the cell apoptosis rate as well as the expression of Bax, caspase-3, and the production of ROS. In vivo, the thinning of the retina and the apoptosis rate in the retina tissue of mice caused by the injection of SI is reversed by the treatment of PA. further, the PA administration caused translocation of Nrf2 and increased the expression of HO-1, and the application of their inhibitors inhibit the effect.
Conclusion
PA protects retinal pigment epithelial (RPE) cells from oxidative stress and apoptosis by activating the NRF2/HO-1 pathway and prevents retinal damage by halting the progression of retinal thinning in mice, which indicating its clinical therapeutic potential in treating AMD.
The Influence of Admission Body Temperature on Prognosis in Sepsis Patients: an analysis from the MIMIC-IV database
Authors: Lu Honglei , Chen Lei , Lv ChenWei , Ni Haibin , Hu Xingxing , Yu Renjun
Published: September 2023

Background This study aimed to investigate the correlation between the mean body temperature during the initial 24 hours of admission and clinical outcomes in septic patients admitted to the Intensive Care Unit (ICU).
Methods This retrospective observational study was conducted using data from the MIMIC-IV (v1.0) database. We extracted the average body temperature of patients with sepsis within the first 24 hours of admission to the Intensive Care Unit (ICU), along with other pertinent clinical data and hospitalization outcomes. To analyze the impact of body temperature on clinical outcomes, patients were categorized into low-temperature, normal, and hyperthermia groups based on different body temperature ranges. To minimize confounding effects, propensity score matching (PSM) was employed, ensuring comparability between the groups. The relationship between abnormal body temperature at admission and clinical outcomes was explored using univariate analysis and logistic regression models to derive robust conclusions.
Results A total of 19,074 patients were included in the analysis. After adjusting for confounding factors, hypothermia (<36°C) was found to be significantly associated with higher 28-day all-cause mortality (35.27% vs. 14.08%), in-hospital mortality (37.21% vs. 15.37%), and ICU mortality (32.04% vs. 10.98%) when compared to the normal body temperature group (p < 0.05). Conversely, the hyperthermia group exhibited a significantly weaker correlation with clinical outcomes than the hypothermia. These results remained robust even after adjusting for confounding factors between the groups.
Conclusion Our study suggests that a hypothermia within the initial 24 hours of admission to the ICU is significantly linked to increased mortality in patients with sepsis, whereas hyperthermia does not exhibit a similar association. Enhancing temperature monitoring during the first 24 hours after admission and avoiding overly aggressive temperature control could prove vital in improving clinical outcomes for sepsis patients.