bluuebunny/crossref_metadata_2025 huggingface dataset:
Perbedaan Tingkat Stres ASN Kota Metro Berdasarkan Jenis Kelamin
Authors: Setiawati Octa Reni , Junaidi Junaidi , Ariska Septa Lia , Mursandi Randi
Published: March 2023

ABSTRACT  Stress is a psychological and physical reaction to any demands that cause stability and tension in everyday life. It is undeniable that humans will experience stress in their lives, one of which is ASN (State Civil Apparatus). Stress on ASN (State Civil Apparatus) can be influenced by several factors, one of which is gender differences. This study aims to determine the relationship between gender and ASN (State Civil Apparatus) stress in Metro city. This research is a quantitative research. Data collection was carried out using the Perceived Stress Scale (PSS) and demographic data. Data were analyzed by hypothesis testing using t-test analysis to determine whether there were differences in the stress level of ASN (State Civil Apparatus) in Metro city based on gender. The conclusion of this study was that the results of this study showed that there was no difference in stress levels in ASN (State Civil Apparatus) both men and women both had the same stress level, with a value (Sig2tailed) of 0.531 ≥ 0.05 Keywords: Gender,Stress, ASN (APARATUR SIPIL NEGARA)  ABSTRAK Stres merupakan suatu reaksi psikologis dan fisik terhadap setiap tuntutan yang menyebabkan gangguan stabilitas dan ketegangan dalam kehidupan sehari-hari. Tidak dapat dipungkiri manusia akan mengalami stres dalam kehidupannya, salah satunya adalah ASN (Aparatur Sipil Negara) (Aparatur Sipil Negara). Stres pada ASN (Aparatur Sipil Negara) dapat dipengaruhi oleh beberapa faktor salah satunya adalah perbedaan jenis kelamin. Penelitian ini bertujuan untuk mengetahui hubungan jenis kelamin dengan stres ASN  (Aparatur Sipil Negara) di kota Metro. Penelitian ini merupakan penelitian  kuantitatif. Pengumpulan data dilakukan dengan menggunakan skala Perceived Stress Scale (PSS) dan data demografi. Data dianalisis dengan uji hipotesis menggunakan analisis uji t-test untuk mengetahui ada tidaknya perbedaan tingkat stres ASN (Aparatur Sipil Negara) kota Metro berdasarkan jenis kelamin. Kesimpulan dari penelitian ini didapati hasil bahwa penelitian ini menunjukkan bahwa tidak adanya  perbedaan tingkat stres pada ASN  (Aparatur Sipil Negara) baik laki-laki ataupun perempuan keduanya memiliki tingkat stres yang sama,dengan nilai (Sig2tailed) sebesar 0.531 ≥ 0,05Kata Kunci: Jenis Kelamin, Stres, ASN (APARATUR SIPIL NEGARA)
The role of absorptive capacity, technological capability, and firm performance in Indonesia’s high-tech industry
Authors: Mursitama Tirta Nugraha , Noerlina  , Arnakim Lili Yulyadi
Published: March 2023

The aim of this research is to examine the role of Absorptive capacity as an important ability to absorb technology and as a key to the firm's innovation capabilities. Technological capability is an important resource that companies must own to increase competitiveness because with these core resources and technology competencies, the firm can create values. Technological capabilities can be developed from internal or external sources. This study focuses on the external source in the form of royalty expense by presenting foreign experts/technology/copyrighted works/trademark/formulas to obtain technology and knowledge transfer. The research uses Large and Medium-scale Manufacturing Survey data that is taken from the Indonesian Central Bureau of Statistics (CBS). This is descriptive research that aims to produce an accurate mechanism of process relationship among variables. The results show that royalty expenses have a different relationship with firm performance. Some industries like electrical equipment and motor vehicles, as well as trailers and semi-trailers, have a very high royalty expense accompanied by the firm’s performance which is also the highest among all industries in the high-tech industry. This proves that several firms in the high-tech industry in Indonesia have a high absorptive capacity. However, different findings are seen in the chemicals and pharmaceutical industry. Firms do not spend above the industry’s average on royalty expenses, but their performance remains above the average performance of the high-tech industry in Indonesia.
Clinical Spectrum and co morbidities of COVID 19 cases admitted at Anwer Khan Modern Medical College Hospital (AKMMCH): A Retrospective record review
Authors: Rahman Md Atiqur , Haque Sayed Tanjilul , Sharmin Sadia , Kawser Abu , Halder Soma , Tajkia Gule , Alam Rajibul , Hoque Ehteshamul , Rahman Md Ekhlasur
Published: March 2023

Background: Coronavirus diseases 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has induced a sense of panic around the world and has been declared Pandemic by the World Health Organization (WHO) on the 11th March 2020. Bangladesh a country of 17 million people is not an exception regarding COVID-19. It has reported around five lacs COVID-19 cases with seven hundreds of deaths. In dealing those challenges AKMMCH has started opening a COVID-19 unit since July 2020 in order to render services for the admitted cases.

Objective: The objective of this study was to explore the clinical spectrum of COVID-19 admitted cases, co morbidities, in addition to selected socio-demographic characteristics under review.

Material and Methods: This descriptive type of retrospective record review was carried out among 1690 COVID-19 confirmed cases during the period of July-December 2020. Data were generated from hospital COVID unit admission records using a checklist. Data entry and statistical analysis were performed manually and by using computer.

Results: The study revealed that majority of the cases was found within age 31-70 years with mean age 52.58 and standard deviation ± 21.7. About 76% cases were male and 24% were female. It also revealed that the clinical spectrum of COVID-19, 63% & 23% cases were moderate and severe cases respectively and only 9% were critically severe. Majority of the cases had chronic illnesses and the most common co-morbidities were Hypertension (44%), Diabetes (26%) and Cardiac diseases (10%).

Conclusion: It may be stated that male persons with more than 52 years of age were mostly affected by COVID-19 diseases. Usually moderate to critically severe patient were admitted in hospital COVID-19 unit for better treatment. Hypertension, Diabetes, Asthma and Cardiac diseases were found as the most common co-morbidities. A comprehensive case management protocol involving allied disciplines (medicine, cardiology, and endocrinology) can be implemented towards improved services and better out come in particular.

AKMMC J 2022; 13(1) : 3-7
Goldenhar syndrome
Authors: Hossain Sanwar , Shahid Zakia Sultana , Guda Titus Leonard , Chowdhury Forhad , Hossain Md Somir
Published: March 2023

Goldenhar Syndrome or Oculoauriculovertebral Syndrome is a complex syndrome characterized by an association of maxillomandibular hypoplasia, deformity of the ear, ocular dermoid and vertebral anomalies and the most severe form of hemifacial microsomia. Here we describe a 12 years female patient with Goldenhar Syndrome came to Ophthalmology department at Anwer Khan Modern Medical College & Hospital.

AKMMC J 2022; 13(1) : 60-64
Development of Bio-Rational Based Management Packages Against Root Knot (Meloidogyne Incognita) Of Bottle Gourd
Authors: Faruk MI
Published: March 2023

The efficacy of Tricho-compost alone and combination of lower dose of Furadan 5G with Tricho-compost, poultry refuse, neem oil cake and saw dust burning against root-knot nematode (Meloidogyne incognita) of bottle gourd was studied in the field laboratory of Plant Pathology Division of Bangladesh Agricultural Research Institute (BARI) during 2017 through 2019 cropping seasons. All the treatments gave appreciable reduction of gall development on roots and enhanced shoot and root growth as well as fruit yield of bottle gourd. Integration of Furadan 5G with Trichoderma based bio-fungicides. Trichocomposts, neem oil cake, and poultry refuse were the effective treatments in reducing root-knot severity and increasing plant growth and fruit yield of bottle gourd.

Bangladesh J. Agril. Res. 46(4): 373-383, December 2021
Effect of Substrates on Growth, Yield and Quality Of Anthurium in Soilless Culture
Authors: Ara KA , Rashid MT , Kabir K , Sadia MA , Sharifuzzaman SM
Published: March 2023

An experiment was conducted at the Floriculture Shade Net House under Horticulture Research Centre of Bangladesh Agricultural Research Institute, Gazipur during 2020-21 to evaluate the effect of different substrates on growth, flowering, yield and quality of anthurium. Six treatments were used viz,. T1: Soil (control), T2: Cocodust, T3: Perlite, T4: Sawdust, T5: Cocodust + Perlite (1:1), and T6: Cocodust + Sawdust (1:1). The experiment was laid out in Completely Randomized Design with five replications. The result showed that Cocodust + perlite (1:1) followed by Cocodust singly performed the best in respect of growth, flower number and quality characteristics of anthurium. Poor performance of all characteristics of anthurium was exhibited in control treatment. Gross return and BCR was the highest in T5 treatment. The result suggested that Perlite + Cocodust (1:1 ratio) followed by Cocodust (100%) could be used for flower yield maximization and quality improvement of anthurium in pot cultivation.

Bangladesh J. Agril. Res. 46(4): 435-443, December 2021
Genotype by Environment Interaction for Yield And Yield Contributing Traits of Finger Millet (Eleusine Coracana) In Bangladesh
Authors: Billah MM , Omy SH , Talukder ZA , Alam MK
Published: March 2023

Stability of for yield and yield contributing traits of finger millet is an important consideration for identification of superior genotypes, which is highly influenced by agro-climatic conditions. The present study was conducted to determine stability for grain yield and yield contributing traits of four finger millet genotypes at three different locations viz; Gazipur, Jamalpur, and Rangpur during 2019-20. In AMMI (Additive Main and Multiplicative Interaction) model, G × E interaction analysis of grain yield and yield contributing traits showed differential interaction of the genotypes in the different environmental conditions. Rangpur and Gazipur were rich for finger millet production while the environment of Jamalpur was poor. Among the genotypes, IE-501 produced the maximum grain yield (5.81 t/ha), followed by IE-2043 (4.69 t/ha) in the favorable environment. Genotypes IE-2043 and IE- 3392 exhibited higher yielding as well as stable over all environments. Considering the AMMI model and mean, bi and S2di, the genotypes IE-2043 and IE-3392 would be suitable across environment whereas genotype IE-501 would be suitable under favorable environmental. For all of the traits evaluated, none of the genotypes were found stable across locations. The genotypes IE- 2043 and IE-3392 with high mean grain yield could be utilized for developing high yielding stable finger millet genotypes.

Bangladesh J. Agril. Res. 46(4): 445-455, December 2021
Combining Ability of Quantitative Traits in Snake Gourd (Trichosanthes Cucumerina Var. Anguina)
Authors: Islam MR , Rahman MM , Zakaria M , Hoque MA , Hasan M
Published: March 2023

The present study was carried out on snake gourd having seven diverse genotypes (TC 01, TC 05, TC 24, TC 33, TC 02, TC 46 and TC 53) used as parental lines and their 21 crosses generated from 7 × 7 half-diallel fashion at Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU) during March to June 2019 following RCBD with three replications. The aim of the study was to determine general combining ability (GCA) and specific combining ability (SCA) for fruit yield and its related traits including fruit quality traits. General prediction ratio (GPR) of these 14 traits was greater than 0.5 (50%), indicating predominance of additive gene effects over non-additive gene effects. The estimates of GCA for 19 quantitative traits revealed that the genotypes P2 and P6 were good general combiners for promoting earliness as well as most other important characters viz., number of fruits/ plant, individual fruit weight and fruit yield/ plant/ hectare; P2 and P6 were also good for fruit length and fruit diameter, respectively whereas, P4 was good for main vine length and number of nodes on main vine while, P3 was superior for long fruit and 100-seed weight whereas, P5 was good for number of seeds/ fruit and P1 good for less fruit fly infestation including individual fruit weight and fruit length. The most promising specific combiners for fruit yield, quality and yield components were from the 13 crosses viz., P1 × P2, P1 × P3, P1 × P4, P1 × P7, P2 × P3, P2 × P5, P2 × P6, P2 × P7, P3 × P7, P4 × P5, P4 × P6, P4 × P7 and P5 × P7. Out of 13 crosses only two crosses namely, P1 × P2 and P2 × P6 had both the good general combiner parents (high × high). These two crosses were therefore, amenable for improvement of the respective traits through pedigree selection. Remaining 11 crosses displaying high SCA effects for different traits were observed to be derived from parents having various types of GCA effects (high × medium, high × low, medium × low and low × low). The results of 13 crosses therefore, indicate the operation of additive × additive, additive × dominant and/ or dominant × dominant gene interactions for the genetic control of expression of the relative traits.

Bangladesh J. Agril. Res. 46(4): 491-510, December 2021
Does Social Awareness Intervention Increase Pro-Environmental Behaviour? An Observational Study
Authors: Asha Saiyeda Asea , Sultana Most Aeysha
Published: March 2023

Pro-environmental behaviour is an indispensable feature for a habitable ecosphere. Thus, the discovery of the ways of enhancing pro-environmental behaviour is crucial. With this motive, the present study aimed to find out the impact of social awareness intervention (displaying cartoons and posters near the dustbin and cafeterias) on pro-environmental behaviour (here, throwing waste into a designated area/bin), where gender difference considered as an elementary factor. Data were gathered using observation (observation without intervention and observation with intervention) to get insight about how pro-environmental behaviour can be enhanced by social awareness. To generate more idea about the other influencing factors, semistructured interview was utilized. A total number of 644 cases were observed and 35 interviews were taken. The results depicted significant effect of social awareness on pro-environmental behaviour (Wald = 25.496, df= 1, p<.001) but no significant effect of gender on pro-environmental behaviour (p = .920). The findings are implementable to improve the pro-environmental behaviour among the Bangladeshi population with basic literacy. Future studies can be conducted using experimental design to gather more precise information about the ways of increasing pro-environmental behaviour.
Social Science Review, Vol. 38(2), December 2021 Page 91-104
Survival of Atlantic salmon and sea trout smolts in transitional waters
Authors: Artero C , Gregory SD , Beaumont WA , Josset Q , Jeannot N , Cole A , Lamireau L , Réveillac E , Lauridsen RB
Published: March 2023

Monitoring the first seaward migration of juvenile salmonids, known as smolts, is challenging because there is limited tracking technology suited to their small size. Nevertheless, for their management and conservation purpose, it is critical to understand this phase of their life cycle when they adapt to increased salinity, novel predators and new prey. Smolts of 2 species, Atlantic salmon Salmo salar and brown trout Salmo trutta, were acoustically monitored at 4 study sites, together with biotic and abiotic parameters, to estimate and explain their survival during their estuarine migration to sea. The 2 species exhibited different levels of survival during this seaward migration, with a higher survival for trout smolts. For both species, survival was similar among 3 of the 4 sites. Migration speed and migratory distance influenced smolt estuarine survival, but body length, body condition, sex, age, and environmental parameters (temperature, salinity, dissolved oxygen) did not. Migration speed, potentially reflecting smolts’ capacity to avoid predators or escape dangerous areas, had a positive effect on their survival. Increased distance negatively influenced estuarine survival, which could lead to lower survival rate in the River Frome Estuary where orientation is more difficult for smolts due to widely separated environmental cues. Overall, smolt survival through estuaries was estimated between 51 and 97% among 4 populations, suggesting that estuaries are variably challenging environments for migrating smolts, accounting for non-negligible early marine survival. Understanding which estuaries have low survival and why is imperative to prioritise management actions.
Sperm Aneuploidy and DNA Integrity: A Review
Authors: Sá Rosália , Sousa Mário
Published: March 2023

Male factors leading to infertility account for at least half of all cases of infertility worldwide. The purpose of this review is to highlight the importance of sperm DNA integrity. A systematic literature search was performed up to January 2015 in order to determine the impact of sperm DNA integrity and of the techniques used to determine it. Only articles presenting sperm aneuploidy together with DNA fragmentation studies are discussed. We also discuss several causes and risk factors that have been identified as having detrimental effects on sperm genetic integrity. Aneuploidy and sperm DNA fragmentation (sDNAfrag) analyses show promising results in determining the sperm genetic status. However, more studies must be performed to develop a technique that can simultaneously verify the sperm DNA integrity and haploidy before introduction into routine clinical practice. Once sperm is subjected to the current technologies it cannot be immediately used in assisted reproduction treatments. However, recent studies have shown that an improved protocol of sperm selection can result in sperm with very low levels of sDNAfrag, rendering the risk of selection low.
https://www.emjreviews.com/reproductive-health/article/new-concepts-in-the-therapeutic-management-of-myoma/
Authors: Hoellen Friederike , Bohlmann Michael K.
Published: March 2023

The therapeutic management of symptomatic uterine fibroids is based on three pillars: surgery, pharmacotherapy, and interventional radiotherapy. Modern myoma treatment is personalised and should involve an interdisciplinary approach according to the patient’s wishes and pathology.
In the Dark: The Afterlife of a Horror Hoax
Authors: Kvistad Erika
Published: March 2023

In the Dark, a 2007 webseries directed by Andrew Cull that purports to be the YouTube channel of a young woman documenting a haunting in her apartment, is arguably the first horror hoax webseries on YouTube. Two decades after the popular rise of two horror media traditions that make use of the storytelling power of hoaxes, the found footage horror film and creepypasta, this article returns to In the Dark as an early work that draws on both these modes and asks: what happens when a hoax gets old? If the credibility of a hoax is inherently time-limited, how might a work of hoax horror whose time has passed speak to us now? To explore the afterlife of In the Dark, I discuss this foundational but little-studied work in the context of earlier scholarship on genres and modes that make use of illusions of authenticity, like creepypasta, found footage film, and alternate reality games (ARGs). I discuss how In the Dark functioned as a hoax when it was originally published in 2007, examining its amateur aesthetics, its interactions with viewers, and its inclusion of apparently meaningless material to create a sense of authenticity and implicate the reader in the storytelling process. Reflecting on how the last fifteen years have changed the way this hoax appears to and works on viewers, I suggest that as the immediate credibility of a horror hoax diminishes, a different kind of horror effect takes over, allowing the hoax to function in new, unintended ways.
LIVING QUR’AN: KREATIVITAS PEMBELAJARAN AL-QUR’AN DAN PENDIDIKAN AGAMA ISLAM
Authors: Al Amin Habibi , Mudawamah Anis
Published: March 2023

The background of this research, creativity and talent in children need to be nurtured and developed. Because with their creativity and talents they can become creative individuals. So that the objectives of this study are: (1) To determine the efforts of teachers in developing student creativity in the subject of Islamic Religious Education. (2) To develop student creativity (3) To determine student supporting and inhibiting factors. This type of research is descriptive in this study, the author uses qualitative methods, with data collection techniques through observation, interview documentation

Keywords:  Living Qur’an Creativity, development, islamic education

 

Abstrak

Latar belakang penelitian ini, Kreativitas dan bakat pada diri anak perlu dipupuk dan dikembangkan. Karena dengan kreativitas dan bakat yang dimilikinya itu mereka dapat menjadi pribadi-pribadi yang kreatif. Sehingga tujuan dari penelitian ini adalah: (1) Untuk mengetahui upaya guru dalam mengembangkan kreativitas siswa dalam mata pelajaran Pendidikan Agama Islam.(2) Untuk mengembangkan kreativitas belajaran siswa (3) Untuk mengetahui faktor pendukung dan penghambat siswa. Jenis penelitian ini adalah Deskriptif dalam penelitian ini, penulis menggunakan metode kualitatif, dengan teknik pengumpulan data melalui observasi, wawancara dokumentasi-dokumentasi.

Kata Kunci: Living Qur’an, Kreativitas, pengembangan, pendidikan islam
ERA SOCIETY 5.0: SUATU TANTANGAN BAGI PENDIDIKAN ISLAM KEKINIAN
Authors: Jumari Jumari , Umam Khoirul
Published: March 2023

Technological developments have an impact on all aspects of human life, including education. Apart from the era of the industrial revolution 4.0, the era of society 5.0 emerged. This requires education to deal with it. Islamic education as a part of education continues to strive in contemporary life to be able to face various challenges that arise. For this reason, how to formulate Islamic education efforts in the era of society 5.0. In this study using literature study by exploring the data based on the discussion becomes part of the data collection technique. This discussion examines the era of society 5.0 and the challenges to contemporary Islamic education. The results of this study: 1) The era of society 5.0 is an era that must be faced, 2) The challenges of contemporary Islamic education must be able to solve various problems through the ability to think critically and analytically, creatively and innovatively in various aspects of life, 3) Efforts that must be made in Islamic education in facing current challenges.

Keywords: Society 5.0, Islamic Education, Challenges, Present

 

Abstrak

Perkembangan teknologi berdampak pada segala aspek kehidupan manusia, termasuk pendidikan. Terlepas dari era revolusi industri 4.0, muncul era masyarakat 5.0. Hal ini membutuhkan pendidikan untuk menghadapinya. Pendidikan Islam sebagai bagian dari pendidikan terus berupaya dalam kehidupan kontemporer untuk mampu menghadapi berbagai tantangan yang muncul. Untuk itu, bagaimana merumuskan upaya pendidikan Islam di era masyarakat 5.0. Dalam penelitian ini menggunakan studi literatur dengan menggali data berdasarkan pembahasan yang menjadi bagian dari teknik pengumpulan data. Diskusi ini mengkaji era masyarakat 5.0 dan tantangan pendidikan Islam kontemporer. Hasil penelitian ini: 1) Era masyarakat 5.0 merupakan era yang harus dihadapi, 2) Tantangan pendidikan Islam kontemporer harus mampu memecahkan berbagai persoalan melalui kemampuan berpikir kritis dan analitis, kreatif dan inovatif dalam berbagai aspek kehidupan, 3) Upaya yang harus dilakukan pendidikan Islam dalam menghadapi tantangan zaman.

Kata Kunci: Society 5.0, ppendidikan Islam, Tantangan, Kekinian
Alternatif Pangan Sebagai Sumber Gizi Dengan Memanfaatkan Umbi Ubi Jalar Ungu (Ipomoea batatas L.) (Sumber Pangan Dengan Indeks Glikemiks Rendah)
Authors: Dipahayu Damaranie , Imtihani Hilya Nur
Published: March 2023

Diabetes mellitus type 2 is the most common degenerative disease in Indonesia, so that the regulation of food intake is important. Food sources of carbohydrates with a low glycemic index (GI) can control blood sugar levels. GI is the rate at which food is absorbed into blood glucose. Purple sweet potato has a low GI so it is suitable as an alternative source of carbohydrates. Different cooking processes can affect the GI of the purple sweet potato, the frying technique produces the lowest GI compared to the boiling or baking technique. The manufacture of hybrid purple sweet potato flour is able to replace the use of wheat flour for processed food products. Hybrid purple sweet potato flour can increase the antioxidant content.
FORMULASI DAN UJI STABILITAS SEDIAAN TONER WAJAH EKSTRAK BUAH PARE (Momordica charantia L) SEBAGAI ANTI JERAWAT DENGAN VARIASI SURFAKTAN
Authors: Noor Muhammad , Malahayati Siti , Nastiti Kunti
Published: March 2023

Bitter gourd extract (Momordica charantia L) contains secondary metabolites such as flavonoids, alkaloids, and saponins that can be antibacterial against acne-causing bacteria (Propionibacterium acnes). Momordica charantia L., could make into facial toner preparations to prevent the emergence and worsen acne. It is formulated with various concentrations of polysorbate 20 and performs stability testing. This study aimed at the optimal formula and analyzed the variations in the concentration effect of polysorbate 20 on the bitter gourd extract facial toner preparation. Bitter gourd extract would make into facial toner preparation with variations in the concentration of polysorbate 20. The accelerated stability test with the cycling test method includes before and after organoleptic, homogeneity, viscosity, and pH tests. The organoleptic stability result shows both stable formulas had the same liquid form, clear brown color, and characteristic rose odor. All formulations are stable on homogeneity, in which the particles are evenly mixed. The Formula I viscosity value is constantly stabilized and meets the parameters, while formula II is not but meets the parameters. The pH stability values of both formulas are stable and meet the parameters. Formula I is more optimal than formula II and the difference in surfactant concentration of polysorbate 20 has no effect on organoleptic, homogeneity, and pH but will affect viscosity.
Pengaruh Perawatan Tali Pusat Metode Topikal ASI dan Kasa Kering Terhadap Waktu Pelepasan Tali Pusat Bayi Baru Lahir Persalinan Post SC
Authors: Liesmayani Elvi Era , Octaviana Lisya , Naibaho Erni
Published: March 2023

Umbilical cord care aims to prevent infection and accelerate the release of the umbilical cord from the baby's stomach. Aim; Knowing the effect of umbilical cord care on the time of release of the umbilical cord with the topical breastfeeding method and cord care with the dry gauze method at Delima General Hospital. Method; The type of research used was "Pre-Experiment" and research design/"static group comparison group". The sampling technique in this study is Accidental Sampling. The number of samples in this study were 30 respondents..Results; Bivariate analysis found that there was an effect of umbilical cord care using topical breast milk and dry gauze on the time of cord extraction, with a value of p = 0.000 <0.05, then Ho was rejected, and when viewed from the t value it was 4.430 while the t table was -2.000 so it was 4.430 > 2,000 (t count > t table) thus Ho is rejected, meaning that there is a significant effect between cord care using topical ASI and dry gauze methods with the time the umbilical cord was removed. Conclusion; There was an effect of umbilical cord care using topical breastfeeding and dry gauze on the time of post-neonatal cord extraction at Delima General Hospital in Medan in 2018. Suggestions for future researchers to develop research with wider variables.
Faktor Yang Memengaruhi Kepatuhan Kunjungan Antenatal Care (ANC) Era Covid 19 di Klinik Madina Tahun 2022
Authors: Nurrahmaton Nurrahmaton , Nasution Pratiwi , Santika Bella
Published: March 2023

The Covid-19 pandemic has greatly changed the status of daily life around the world and for working from home via the internet. WHO in 2019 stated that the maternal mortality rate in the world was 830/100,000 live births. The purpose of this study was to determine the factors that influence compliance with ANC visits in the Covid-19 era at the Madina clinic in 2022. The research design used in this study was an analytic survey with a cross-sectional approach. The population in this study were third trimester pregnant women as many as 36 respondents. The sample uses a Total Population of 36 people. Data analysis techniques used Univariate and Bivariate Analysis. The results showed that there was an effect between knowledge and ANC visit compliance with statistical test results obtained p-value = 0.003, there was an effect between attitudes towards ANC visit compliance p-value = 0.009, there was an effect between employment status on adherence to ANC visits p-value = 0.021, and there is an effect between the support of health workers on compliance with ANC visits p-value = 0.011 Conclusion: There is a significant influence between knowledge, attitudes, employment status and support of health workers on adherence to ANC visits at the Madina clinic in 2022 It is hoped that the health workers at the Madina clinic will play an active role in ANC services
Faktor-Faktor yang Berhubungan dengan Perilaku Pencegahan Keputihan pada Akseptor KB Hormonal di Puskesmas Rawang Barat Tahun 2018
Authors: Septina Cindy Audia , Saputri Lita Angelina , Doni Alsri Windra
Published: March 2023

Leucorrhoea is discharge from the genitalia that is not blood. It is estimated that 75% of women in Indonesia have experienced vaginal discharge. Leucorrhoea will increase by 50% due to the use of hormonal contraception. In Padang City, the coverage of active family planning acceptors is quite high, namely the Rawang Barat Health Center. namely 4,154 (90.59%). The aim of the study was to determine the factors associated with leucorrhoea prevention behavior in hormonal birth control acceptors at the Rawang Barat Health Center in 2018. This type of research was an analytic survey with a cross-sectional design. The population is all active hormonal family planning acceptors with a total sample of 60 people at the Rawang Barat Health Center which was conducted in January-March 2018. The sampling technique was accidental sampling. The research instrument used a questionnaire with bivariate analysis with the Chi Square statistical test. The results showed that 55% of respondents had high knowledge, 51.7% had a positive attitude, 61.7% were less exposed to information about leucorrhoea prevention behavior. Variables that have a relationship with leucorrhoea prevention behavior are knowledge (p=0.000), attitude (p=0.000), while variables that are not related are information exposure (p=0.432). Conclusion: there are still respondents with low knowledge, attitudes, and information exposure. It is suggested that there is a need for more explanation and explanation regarding leucorrhoea in the form of counseling by health workers.
Sistem Monitoring Online Dan Analisis Perfomansi Plts Panel Surya Monocrystalline 100 Wp Berbasis Web
Authors: Duanaputri Rohmanita , Heryanto/Eryk Irwan , Sajidan Muhammad Firas , Ayusta Lukita Wardani
Published: March 2023

In this modern life, people's dependence on energy sources, especially electrical energy, has led to innovation in the use of cheap alternative energy sources that are environmentally friendly such as solar energy, one of which is PLTS. To support PLTS performance, a web-based monitoring system is needed for remote monitoring in monitoring PLTS performance, the data displayed is the result of measurements by voltage and current sensors installed in each solar panel on the PLTS performance detector. In this case, it is necessary to develop a Web-based monitoring system to help improve the efficiency of performance maintenance on 100 wp monocrystalline panels. By using the INA260 sensor in the form of a digital DC sensor that can measure a maximum current of 15 A, a maximum voltage of 36 v, and DC power and the DS18B20 sensor is a digital sensor that can measure the surface temperature of the panel. Sensor readings can be displayed offline via the HMI LCD while online readings can be displayed in the form of a Web which has a graphical display feature for each parameter and downloads data in the form of a .csv file as a feature that supports data analysis. The results of the sensor validation test or calibration using a measuring instrument have an average error sensor reading of 0.34 %. The average current sensor error is 0.63%, and the power sensor error average is 0.56%, while the average panel surface temperature sensor error is 0.34%
Kapasitor Shunt Sebagai Korektor Tegangan Bus di Gardu Induk
Authors: Muhammad Fahmi Hakim  , Slamet Nurhadi  , Hanifiyah Darna Fidya Amaral  , Satria Luthfi Hermawan
Published: March 2023

Segoromadu Substation has two busbars, namely busbar A and busbar B. Busbar A which has nominal voltage of 150 kV has reached a voltage value of 129.38 kV or experienced voltage drop of 13.75%. The percentage of this voltage drop exceeds a predetermined standard. Therefore, it is necessary to design a shunt capacitor which is then modeled and simulated. Based on calculation and analysis result, capacity of shunt capacitor that should be installed on Bus A is 50 MVAR. After the shunt capacitor was installed, based on simulation, there was an increase of 4.87 kV so the voltage afterward became 139.67 kV or only experienced a voltage drop of 3.19%. So, by installing a shunt capacitor with capacity of 50 MVAR, it can increase busbar voltage of the substation. The shunt capacitor also increases the value of reactive power and current flowing to the busbar.
Combined effects of alkaline pH and high Ca concentration on root morphology, cell-wall polysaccharide concentrations and blueberry plant performance
Authors: Tamir Guy , Zeng Qilong , Eli Dagan , Zilkah Shmuel , Bar-Tal Asher , Dai Nir
Published: March 2023

The appropriate soil pH for blueberry production is <5.5. However, the exact factors involved in the retardation of blueberry growth at higher pH levels have not yet been completely identified. In this study, we examined the short- and long-term combined effects of pH level and Ca concentrations on root morphology and development in relation to blueberry plant performance. Southern highbush blueberry (Vaccinium corymbosum, cv. Windsor) plants were grown in solutions of pH 4.5 or 7.5 that contained 0, 5, 10, 50 or 100 mg L-1 of Ca. The dimensions of the epidermal cell walls of the roots and the levels of pectin and hemicellulose 1 and 2 in those cells were determined after 1 and 3 days. Concentrations of essential macro and micro-elements in the plant organs, chlorophyll concentrations in the leaves and whole-plant biomass production were measured after 12 weeks. The results demonstrate a rapid (3 days) negative response of root tips at pH 7.5 expressed as reduced dimensions and deformation of the epidermal cell walls. This response was accompanied by reduced concentrations of pectin and hemicellulose 1 in those cell walls. These negative effects of pH 7.5 were amplified by a 100 mg L-1 of Ca over the long term (12 weeks), where the concentrations of P and Ca on the epidermal cell of the root were increased. Additionally, the translocation of Mn from the root to the shoot was retarded. The negative effect of the pH level on roots development and on the Mn translocation were associated with significant reductions in chlorophyll concentrations and biomass production. The results presented in this study demonstrate, for the first time, the negative effect of the combination of slightly alkaline pH and a high Ca concentration on root development, which associated with retarding blueberry plants performance.
Emerging trends and hotspots evolution in cardiotoxicity: A bibliometric and knowledge-Map analysis From 2010 to 2022
Authors: Xiao Di , Li Jingen , Liu Yong , Wang Tangshun , Niu Chaofeng , Zhuang Rui , Liu Birong , Ma Liyong , Li Meng , Zhang Lijing
Published: March 2023

Background

There is growing emphasis on the cardiotoxicity research over the past 12 years. To look for the hotspots evolution and to explore the emerging trends in the field of cardiotoxicity, publications related to cardiotoxicity were acquired from the Web of Science Core Collection on August 2, 2022.

Methods

We used the CiteSpace 5.8 R3 and VOSviewer 1.6.18 to perform bibliometric and knowledge-map analysis.

Results

A total of 8,074 studies by 39,071 authors from 6,530 institutions in 124 countries or regions were published in different academic journals. The most productive country was absolutely the United States, and the University of Texas MD Anderson Cancer Center was the institution with the largest output. Zhang, Yun published the most articles, and the author who had the most frequent co-citations was Moslehi, Javid. New England Journal of Medicine was the most frequently cited journals in this field. Mechanisms of cardiotoxicity have received the most attention and was the main research directions in the field. The disease of cardiotoxicity together with the related risk factors are potential research hotspots. Immune checkpoint inhibitor and myocarditis are two recently discussed and rapidly expanding research topic in the areas of cardiotoxicity.

Conclusions

This bibliometric analysis provided a thorough analysis of the cardiotoxicity, which would provide crucial sources of information and concepts for academics studying this area. As a rapidly expanding field in cardiology, the related field of cardiotoxicity will continue to be a focus of research.
The bidirectional relationship between endometriosis and microbiome
Authors: Uzuner Cansu , Mak Jason , El-Assaad Fatima , Condous George
Published: March 2023

Endometriosis has been described by many different theories of pathogenesis over the years. It is now also appreciated to be a state of chronic inflammation, and the role of immune dysfunction in its development has been proven. There is increasing evidence to support the role of the microbiome in the formation and progression of endometriosis via inflammatory pathways. The dysbiosis seen in endometriosis is thought to be both causative and a consequence of the pathogenesis. Gut, peritoneal fluid and female reproductive tract microbiota has been studied to understand if there are any microbiome signatures specific to endometriosis. New research on how to manipulate the microbiome for better detection and treatment of endometriosis is emerging.
Theoretical and simulation analysis on the spatial resolution of magnetic metal debris sensors
Authors: Ren Yijun , Wen Xiaolong , Gao Shengwei , Liu Yongbin , Ju Bin
Published: March 2023

Inductive debris sensor is becoming increasingly important in online oil debris detection. This work proposes a new criterion for evaluating the performance of an inductive oil debris sensor: spatial resolution. When multiple metal particles in lubricating oil simultaneously pass through the sensor, it is vital that clear signals responding to each particle are produced. The spatial resolution is referred to the allowable distance between two particles when the sensor can accurately distinguish the particle signals. Theoretical analysis shows that spatial resolution has a relationship with the output signal of a single particle. A COMSOL model is established to simulate a coil output when two adjacent particles pass, and the output signals change with the distance between two particles, the particle size and the coil structures. Results show that the relevant factors affecting the spatial resolution, and a small coil radius can help improve the sensor’s accuracy of debris identification.
Combined flow cytometry natural killer immunophenotyping and KIR/HLA-C genotyping reveal remarkable differences in acute myeloid leukemia patients, but suggest an overall impairment of the natural killer response
Authors: Cianga Vlad Andrei , Rusu Cristina , Pavel-Tanasa Mariana , Dascalescu Angela , Danaila Catalin , Harnau Sebastian , Aanei Carmen-Mariana , Cianga Petru
Published: March 2023

Introduction

Natural killer (NK) cells are key anti-tumor effectors of the innate immunity. Phenotypic differences allow us to discriminate in between three functional stages of maturation, named immature, mature and hypermature that are distinctive in terms of receptor expression, cytokine secretion, cytotoxic properties and organ trafficking. NKs display an impressive repertoire of highly polymorphic germline encoded receptors that can be either activating, triggering the effector’s function, or inhibitory, limiting the immune response. In our study, we have investigated peripheral blood NK cells of acute myeloid leukemia (AML) patients.

Methods

The Killer Immunoglobulin-like receptors (KIRs) and the HLA-C genotypes were assessed, as HLA-C molecules are cognate antigens for inhibitory KIRs.

Results

The AA mainly inhibitory KIR haplotype was found in a higher proportion in AML, while a striking low frequency of the 2DS3 characterized the mainly activating Bx haplotype. Flow cytometry immunophenotyping evidenced a lower overall count of NK cells in AML versus healthy controls, with lower percentages of the immature and mature subpopulations, but with a markedly increase of the hypermature NKs. The analysis of the KIR2DL1, KIR2DL2, KIR2DL3, KIR3DL1, and NKG2A inhibitory receptors surface expression revealed a remarkable heterogeneity. However, an overall trend for a higher expression in AML patients could be noticed in all maturation subpopulations. Some of the AML patients with complex karyotypes or displaying a FLT3 gene mutation proved to be extreme outliers in terms of NK cells percentages or inhibitory receptors expression.

Discussion

We conclude that while the genetic background investigation in AML offers important pieces of information regarding susceptibility to disease or prognosis, it is flow cytometry that is able to offer details of finesse in terms of NK numbers and phenotypes, necessary for an adequate individual evaluation of these patients.
Dietary administration with hydrolyzed silk sericin improves the intestinal health of diabetic rats
Authors: Zhou Wenlin , Weng Yujie , Liu Qian , Wang Chonglong , Zhang Yu-Qing , Zhang Xing , Ye Aihong
Published: March 2023

Type II diabetes (T2D) is a global epidemic disease with an increased incidence and prevalence. Gut microbiota plays an important role in controlling T2D development. Dietary administration of prebiotics, probiotics, and drugs, including metformin, showed the regulatory impact on the change of gut microbiota, which is associated with the improvement of glucose tolerance. In this study, silk sericin was manufactured into hydrolyzed sericin peptide (HSP) powders as a dietary additive to investigate the effect on the gut microbiota of T2D model rats. The results indicated that the HSP-augmented dietary administration lowers the fast glucose level of diabetic rats, and HSP augmentation induces a change in the gut microbiota composition of T2D model rats toward the normal rats. Some key taxa, including Lactobacillus gasseri, were suggested to be involved in controlling T2D development. This finding provides new insight into developing sericin as functional food or therapeutic prebiotics against T2D in clinical practice.
The multiple roles of GH in neural ageing and injury
Authors: Blackmore Daniel G. , Waters Michael J.
Published: March 2023

Advanced age is typically associated with a decrease in cognitive function including impairment in the formation and retention of new memories. The hippocampus is critical for learning and memory, especially spatial learning, and is particularly affected by ageing. With advanced age, multiple neural components can be detrimentally affected including a reduction in the number of neural stem and precursor cells, a decrease in the formation of adult born neurons (neurogenesis), and deficits in neural circuitry, all of which ultimately contribute to impaired cognitive function. Importantly, physical exercise has been shown to ameliorate many of these impairments and is able to improve learning and memory. Relevantly, growth hormone (GH) is an important protein hormone that decreases with ageing and increases following physical exercise. Originally described due to its role in longitudinal growth, GH has now been identified to play several additional key roles, especially in relation to the brain. Indeed, the regular decrease in GH levels following puberty is one of the most well documented components of neuroendocrine ageing. Growth hormone deficiency (GHD) has been described to have adverse effects on brain function, which can be ameliorated via GH replacement therapy. Physical exercise has been shown to increase circulating GH levels. Furthermore, we recently demonstrated the increase in exercise-mediated GH is critical for improved cognitive function in the aged mouse. Here we examine the multiple roles that GH plays, particularly in the aged brain and following trauma, irradiation and stroke, and how increasing GH levels can ameliorate deficits in cognition.
The patent foramen ovale may alter migraine brain activity: A pilot study of electroencephalography spectrum and functional connectivity analysis
Authors: Lei Xiangyu , Wei Meng , Qi Yi , Wang Liang , Liu Chenyu , Guo Yichen , Xu Yue , Cao Xiangqi , Liu Rui , Luo Guogang
Published: March 2023

Background

A link has been shown between patent foramen ovale (PFO) and migraine, particularly migraine with aura. However, it is unknown if PFO might cause migraine by altering cortical excitability and neural network, which may lower the threshold of cortical spreading depression (CSD). This study aims to compare the spectrum power and functional connectivity of the alpha and beta bands of electroencephalography (EEG) across migraine patients with and without PFO.

Methods

Thirty-five migraine patients with PFO (PFO +), 35 migraine patients without PFO (PFO –) and 20 PFO patients without migraine (control) were enrolled in this cross-sectional analysis. 19-channel EEG was recorded for all patients under resting state and intermittent photic stimulation. Power spectrum density (PSD) and phase lag index (PLI) of alpha and beta bands were then calculated and compared between the three groups.

Results

During photic stimulation, the beta band PSD at the occipital area was substantially higher in PFO + migraine patients compared to PFO-migraine patients (p < 0.05, Bonferroni corrected). Subgroup analysis showed that both migraine with and without aura patients with PFO had increased PSD in the alpha and beta bands at the occipital region during photic stimulation (p < 0.05, Bonferroni corrected). Meanwhile, the beta band PLI during photic stimulation was significantly elevated (adjusted p = 0.008, utilizing the network-based statistic technique) in PFO + group compared to PFO-group. Furthermore, although failed to pass the correction, the beta band power in the occipital area during photic stimulation at 20 Hz on O1 (R = 0.392, p = 0.024) and O2 channel (R = 0.348, p = 0.047) was prone to positively correlated with MIDAS score, and during photic stimulation at 12 Hz on O2 channel (R = 0.396, p = 0.022) and 20 Hz (R = 0.365, p = 0.037) on O1 channel was prone to positively correlated to HIT-6 score in PFO+ migraineurs, whereas no similar correlation was found in the PFO-group patients.

Conclusion

The outcomes of this investigation suggested that PFO may change the cortical excitability in the occipital lobe of both migraineurs with and without aura. Meanwhile, the beta band PSD on the occipital area during photic stimulation might be an objective measure of severity in migraineurs with PFO.