bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis, Characterization, and X‐Ray Structure of the Octahedral Nickel(II) Complex of a Pentadentate Hexaaza Macrobicyclic Ligand: Chloro(9‐(methoxymethyl)‐1,4,6,9,11,14‐hexaazabicyclo(12.2.1)heptadecane)nickel(II) Perchlorate.
Authors: SUH M. P. , CHOI J. , KANG S.‐G. , SHIN W.
Published: May 2016

The template condensation reaction in the mole ratios given in the scheme produces the title complex (VI) as a first example of a hexaaza macrocycle which serves as a pentadentate ligand.
ChemInform Abstract: Triple‐Decker Complexes. Part 11. (η3‐Allyl)nickel(μ,η5‐2,3‐dihydro‐1,3‐diborolyl)nickel(η3‐allyl)# (η1‐allyl) Triple‐Decker Complexes.
Authors: BRODT G. , KUHLMANN T. , SIEBERT W.
Published: May 2016

(IIIb) is obtained analogously to (IIIa) in Et2O at ‐40 °C. The bonding in (III) is elucidated by 1H and 13C NMR data.
ChemInform Abstract: Novel Basic Ligands for the Homogeneous Catalytic Methanol Carbonylation. Part 21. Synthesis and Properties of (Ether‐Phosphane) Platinum Complexes.
Authors: LINDNER E. , SPEIDEL R.
Published: May 2016

The ether‐phosphane‐Pt(II) complexes (III) are prepared according to the scheme; they can also be obtained similarly starting with PtCl2(cod).
ChemInform Abstract: Preparation and X‐Ray Structure of (dbuH) (PtBr5(PPh3)).
Authors: MOTEVALLI M. , HURSTHOUSE M. B. , KELLY P. F. , WOOLLINS J. D.
Published: May 2016

In contrast to analogous complexes of smaller phosphines, which react with bromine to give Pt(IV) dibromo species, the Pt(II) complex (I) reacts with Br2 to afford PtBr2(PPh3)2 and PtBr4(PPh3)2 and, if performed in the presence of the hydrochloride of DBU, the title complex (IV).
ChemInform Abstract: C‐Glycosides. Part 7. Stereospecific C‐Glycosylation of Aromatic and Heterocyclic Rings.
Authors: CZERNECKI S. , VILLE G.
Published: May 2016

Reaction of the D‐glucopyranolactone (I) with the aryl and hetaryl lithium compounds (II) gives anomeric mixtures of the D‐glucopyranoses (III) which are stereospecifically reduced with triethylsilane to form the β‐glycosides (IV).
ChemInform Abstract: Thiazole Route to Carbohydrates: Synthesis of Building Blocks or Precursors to Carbohydrates with the Use of Functionally‐Substituted Thiazoles as Auxiliaries. Part 1. Iterative, Stereoselective Homologation of Chiral Polyalkoxy Aldehydes Employing 2‐(Trimethylsilyl)thiazole as a Formyl Anion Equivalent. The Thiazole Route to Higher Carbohydrates.
Authors: DONDONI A. , FANTIN G. , FOGAGNOLO M. , MEDICI A. , PEDRINI P.
Published: May 2016

Addition of 2‐trimethylsilylthiazole (II) to the chiral aldehydes (I) leads to the formation of the intermediates (III) which give the anti‐(α‐hydroxyalkyl)thiazoles (IV) with high diastereofacial selectivity after desilylation.
ChemInform Abstract: Chromenes. Part 7. Product Stabilization in Condensations with 7‐Methoxy‐2,2‐dimethylchroman‐4‐one.
Authors: ANASTASIS P. , BROWN P. E. , ISLAM Q. , MARCUS W. Y.
Published: May 2016

The condensation of the enolate anion of compound (I) with the aldehydes (II) leads to stable products only in the presence of ZnCl2.
ChemInform Abstract: Effect of Powder Surface Chemistry on the Stability of Concentrated Aqueous Dispersions of Alumina.
Authors: KELSO J. F. , FERRAZZOLI T. A.
Published: May 2016

It is shown that the initial dispersion pH and the magnitude and sign of the initial mobility (zeta potential) of the dispersion are strongly influenced by the surface chemistry of ceramic powders.
ChemInform Abstract: FXeOIOF4 and Xe(OIOF4)2: Preparation and Study by 129Xe and 19F NMR Spectroscopy and Raman Spectroscopy and NMR Characterization of LXeOIOF4 (L: ‐OTeF5, ‐OSO2F).
Authors: SYVRET R. G. , SCHROBILGEN G. J.
Published: May 2016

The 129Xe and 19F NMR results obtained for solutions containing varying amounts of IO2F3 and XeF2 in SO2ClF, CFCl3, and BrF5 solvents show that IO2F3 inserts into the Xe‐F bond of XeF2 to yield the pseudooctahedral cis‐ and trans‐OIF4O oxygen bonded Xe(II)‐derivatives (I)‐(V); their relative amounts depend on both temp. and solvent polarity.
ChemInform Abstract: Photocatalytic Hydrogen Evolution from Aqueous Solutions of Sodium Sulfite Using Platinum‐Loaded CdS1‐xSex Mixed Crystal Powder.
Authors: UCHIHARA T. , ABE H. , MATSUMURA M. , TSUBOMURA H.
Published: May 2016

CdS1‐xSex (x = 0‐1.0) powders are prepared in order to reduce the band gap of CdS and to broaden the effective wavelength range of the photocatalyst.
ChemInform Abstract: Effect of Benzotriazole on Dissolution of Copper in the Presence of Fluid Flow. Part 1. Experimental.
Authors: ALKIRE R. , CANGELLARI A.
Published: May 2016

Electrochemical measurements indicate that during the inhibition of anodic Cu dissolution by benzotriazole a dual layer forms on the Cu surface.
ChemInform Abstract: Effect of Inert Gas Flow Rate on the Inorganic Bromate Oscillator.
Authors: ADAMCIKOVA L. , SEVCIK P.
Published: May 2016

The oscillation behavior of a purely inorganic oscillator (Belousov‐Zhabotinsky‐type: NaBrO3‐NaH2PO2‐Mn(II)‐H2SO4) is investigated, using various flow rates of an inert carrier gas (N2) to remove the gaseous products.
ChemInform Abstract: Investigations of Solid State Reactions of Binary Polyphosphate‐Fluoride Systems by Means of Thermal Analysis, X‐Ray Diffraction and NMR Spectroscopy. Part 4. Systems M(PO3)3 + MF3 (M: Al, La).
Authors: EHRT D. , JAEGER C. +
Published: May 2016

The reaction outlined in the scheme is found to be the main reaction within the title systems.
ChemInform Abstract: 13C NMR Study of Amino and Phosphino Substituted Acetylenes: δ(13C), JCC and JCP.
Authors: KAMIENSKA‐TRELA K. , BIEDRZYCKA Z. , MACHINEK R. , LUETTKE W. +
Published: May 2016

An inspection of experimental and theoretical 1JC≡C values shows that the CC couplings across the triple bond of the compounds (I) are governed by the electronegativity of the substituents attached to the triple bond.
ChemInform Abstract: On the Tautomerism of 2‐Phenacyl‐4‐pyrimidinones and Related Compounds.
Authors: ELGUERO J. , GOYA P. , MARTINEZ A. , ROZAS I.
Published: May 2016

According to 1H and 13C NMR data, the title compounds (I) exist exclusively as the benzoylmethylene tautomers as given in the scheme both in solution and in the solid state.
ChemInform Abstract: The Synthesis of 1‐Benzyldimethylsilyl‐4‐phenylthio‐1,3‐butadiene: A New Diene‐Regenerable Diels‐Alder Synthon.
Authors: PEGRAM J. J. , ANDERSON C. B.
Published: May 2016

The butadienes (VI), prepared as outlined in the reaction scheme, react with the dienophile methyl methacrylate (VII) to give a diastereomeric mixture of the cyclohexenes (VIII) and (IX) which is converted to the cyclohexadiene (X).
ChemInform Abstract: Tetraphenylstibonium Triflate as a Regio‐ and Chemoselective Catalyst in the Reaction of Oxiranes with Amines.
Authors: FUJIWARA M. , IMADA M. , BABA A. , MATSUDA H.
Published: May 2016

Cyclohexene oxide (I) is cleaved by the amines (II) in the presence of tetraphenylstibonium triflate to form the trans‐aminocyclohexanols (III).
ChemInform Abstract: The Pyrolysis of Tetraphenylphthalic Anhydride: Formation of 1,2,3‐Triphenylbenzopentalene.
Authors: BROWN R. F. C. , COULSTON K. J. , EASTWOOD F. W. , KORAKIS T.
Published: May 2016

The flash vacuum pyrolysis of tetraphenylphthalic anhydride (I) produces 1,2,3‐triphenylbenzopentalene (IV) and not 1,2,3‐triphenylbiphenylene (V) as reported in the literature.
ChemInform Abstract: Direct Formation of Epoxyalkylcopper Reagents from Activated Copper and Epoxyalkyl Bromides and Their Intramolecular Cyclizations.
Authors: WU T.‐C. , RIEKE R. D.
Published: May 2016

The 6‐bromo‐1,2‐epoxyhexanes (Ia) and (Ib) react with activated copper via the corresponding intermediate 1,2‐epoxyhexylcopper derivatives to give the isomeric alcohols (II) and/or (III).
ChemInform Abstract: Metal‐Promoted Cyclization. Part 22. Synthesis of Benzofurans, Tetrahydrobenzopyrans, and Related Cyclic Ethers via Cyclic Carbopalladation.
Authors: NEGISHI E. , NGUYEN T. , O'CONNOR B. , EVANS J. M. , SILVEIRA A. JUN.
Published: May 2016

Pd‐catalyzed cyclization of various iodine‐substituted (homo)allyl ethers produces 5‐ and 6‐membered O‐heterocycles as shown in the reaction scheme.
ChemInform Abstract: Carbonyl Radical Cyclizations: Preparation of Some Heterocyclic Ketones.
Authors: CRICH D. , EUSTACE K. A. , RITCHIE T. J.
Published: May 2016

Treatment of the allylic selenol esters (I) with tributyltin hydride in the presence of AIBN results in cyclization, producing the heterocycles (II).
ChemInform Abstract: Photochemical C‐H Bond Activation of Coordinated Propene in (η5‐C5Me5)Re(CO)2(η2‐C3H6). X‐Ray Structure Determination of Exo and Endo Isomers of the Resulting η3‐Allyl(hydrido) Complex (η5‐C5Me5)Re(H)(CO)(η3‐C3H5).
Authors: BATCHELOR R. J. , EINSTEIN F. W. B. , JONES R. H. , ZHUANG J.‐M. , SUTTON D.
Published: May 2016

The crystals of exo‐(II) and endo‐(III) are composed of equal amounts of the R‐ and S‐enantiomers.
ChemInform Abstract: 4,3‐Additions to α,β‐Unsaturated Ketones via η2 C=C Binding to a Ruthenium Complex.
Authors: TANKE R. S. , CRABTREE R. H.
Published: May 2016

The ruthenium complex (I) reacts with ethyl vinyl ketone (II) and silver hexafluoroantimonate to give the ruthenium olefin complex (III) which on reduction with sodium cyanoboranate yields the ruthenium complex (IV).
ChemInform Abstract: Synthesis of Allylic Sulfides and Selenides by Lewis Acid‐Mediated Displacement Reactions of Sulfones.
Authors: SIMPKINS N. S.
Published: May 2016

The sulfonyl selenide (I) and the sulfonyl sulfide (IV) are substituted to form the corresponding products (III) and (V) which react with trimethylallylsilane (VI) to give the allyl‐substituted sulfides (VII) or selenides (VIII).
ChemInform Abstract: Facile and Convenient Syntheses of Quinones from Phenols.
Authors: MINISCI F. , CITTERIO A. , VISMARA E. , FONTANA F. , DE BERNARDINIS S. , CORREALE M.
Published: May 2016

The dihydroxybenzenes(naphthalenes) (I) and (III) are oxidized with hydrogen peroxide in the presence of iodine and conc.
ChemInform Abstract: Reactivity of Fluoroolefins in Base‐Catalyzed Reactions with Oxiranes.
Authors: SOLOV'EV D. V. , DOKUCHAEV P. YU. , RODIN A. A. , MUSHENKO V. D. , LAVRENT'EV A. N.
Published: May 2016

Reaction of the fluoroolefins (I) with the phenyl glycidyl ether (II), catalyzed by CsF or KHF2, is not selective but produces complex mixtures of products containing only a small amount of the phenyl ethers (III).
ChemInform Abstract: Preparation of Substituted 2‐Aminooxazole‐4‐carbonitriles.
Authors: PASCUAL A.
Published: May 2016

During a synthetic program to convert thioureas of type (I) into the carbodiimides (II), a side reaction leading to the aminooxazole carbonitriles (III) is observed.
ChemInform Abstract: Reactions of Quaternized Imidazo‐Quinazoline and ‐Pyridopyrimidine with Active Methylene Compounds.
Authors: DOBNIKAR M. , KOCEVAR M. , PETRIC A. , TISLER M. , VERCEK B.
Published: May 2016

The title compounds (III) are prepared.
ChemInform Abstract: Fluoronaphthyridines and Quinolones as Antibacterial Agents. Part 1. Synthesis and Structure‐Activity Relationships of New 1‐Substituted Derivatives.
Authors: BOUZARD D. , DI CESARE P. , ESSIZ M. , JACQUET J. P. , REMUZON P. , WEBER A. , OKI T. , MASUYOSHI M.
Published: May 2016

Starting with the ester (I), a series of N‐substituted quinolones (VII) is prepared as shown in the reaction scheme.
ChemInform Abstract: Pentacoordinated Molecules. Part 76. Novel Hydrolysis Pathways of Dimesityldifluorosilane via an Anionic Five‐Coordinated Silicate and a Hydrogen‐Bonded Bisilonate. Model Intermediates in the Sol‐Gel Process.
Authors: JOHNSON S. E. , DEITERS J. A. , DAY R. O. , HOLMES R. R.
Published: May 2016

Dimesityldifluorosilane (I) does not react with water in refluxing acetonitrile.
ChemInform Abstract: A New Cobalt‐Sulfur Cluster with Triphenylphosphine. Preparation and Structure of Co6S8(PPh3)6.
Authors: HONG M. , HUANG Z. , LEI X. , WEI G. , KANG B. , LIU H.
Published: May 2016

The paramagnetic title cluster is obtained by 1:1 molar reaction of CoBr2(PPh3)2 with Na2Sx in DMF and characterized by X‐ray structure analysis (space group P1, Z=1).
ChemInform Abstract: Coordination Chemistry of the Nitronyl and Imino Nitroxides. Linear Chain Adducts with Rhodium(II) Trifluoroacetate Dimer.
Authors: COGNE A. , GRAND A. , REY P. , SUBRA R.
Published: May 2016

The adducts (I)‐(IV) of rhodium trifluoroacetate dimer with nitroxyl free radicals are prepared (yields 87, 69, 47, 58%) and their structural and magnetic properties studied.
ChemInform Abstract: Sterically Congested Ligands: Synthesis and Spectral Characterization of the First Pd(II) and Pt(II) Complexes of Tetra‐tert.‐butyl‐substituted Biaryloxybis(1,3,2‐oxazaphospholidine).
Authors: PASTOR S. D. , TOGNI A.
Published: May 2016

The 1:1 molar reaction of PdCl2(NCMe)2 or PtCl2(cod) with the title ligand in benzene at 0 °C leads to a mixture of the cis and trans isomers (I) and (II) as well as to only the cis‐Pt compound (III).
ChemInform Abstract: β‐Cleavage of Potassium Bicyclo(2.2.2)oct‐5‐en‐2‐olates. Stereoselective Synthesis of (.+‐.)‐Trichodiene.
Authors: SNOWDEN R. L. , BRAUCHLI R. , SONNAY P.
Published: May 2016

Ca. 10 differently substituted bicyclo(2.2.2)oct‐5‐en‐2‐olates are subjected to the title reaction, but only (Ia) and (Ib) are shown to give the products (II) with > 15% yield.
ChemInform Abstract: Synthesis of 4‐Seleno‐D‐fructose Derivatives and an Investigation of Their Utility as Precursors of Unsaturated Hexulofuranosides.
Authors: MARTIN O. R. , RAFKA R. J. , SZAREK W. A.
Published: May 2016

The seleno‐D‐fructose derivatives (III) and (VI) are prepared by cleavage of the epoxide ring of the furanoside (I) with phenyl selenide (II).
ChemInform Abstract: Benzophenanthridines. Part 6. Conversions of Protoberberine Alkaloids to Benzo(c)phenanthridine Alkaloids. Hofmann Cleavage of α‐N‐ and β‐N‐Methyl‐(.+‐.)‐13α‐hydroxyxylopininium Iodides.
Authors: SLADKOV V. I. , SAZONOVA N. M. , KULESHOVA L. N. , LINDEMAN S. V. , STRUCHKOV YU. T. , SUVOROV N. N.
Published: May 2016

Starting from the dihydropapaverine (I) the α‐hydroxy‐norlaudanosine (II) is prepared, which is smoothly converted to (±)‐13‐α‐hydroxyxylopinine (IV) and thence to a separable 3:1 mixture of the cis‐ and trans‐dibenzoquinolizidinium iodides (VI) and (VII) (1H, 13C NMR data; X‐ray analysis of (VII): space group P1 with Z=2).
ChemInform Abstract: A Highly Stereoselective Synthesis of (+)‐Olivin, the Aglycon of Olivomycin A.
Authors: ROUSH W. R. , MICHAELIDES M. R. , TAI D. F. , LESUR B. M. , CHONG W. K. M. , HARRIS D. J.
Published: May 2016

The first total synthesis of (+)‐olivin (XIII), the naturally occurring enantiomer of the aglycon of the antitumor antibiotic olivomycin A, is described.
ChemInform Abstract: Structural Characterization of Colloidal Platinum by High Resolution Electron Microscopy and EXAFS Analysis.
Authors: DUFF D. G. , EDWARDS P. P. , EVANS J. , GAUNTLETT J. T. , JEFFERSON D. A. , JOHNSON B. F. G. , KIRKLAND A. I. , SMITH D. J.
Published: May 2016

It is found that most of the Pt particles of a platinum sol have a structure based on a face‐centered cubic packing.
ChemInform Abstract: Analysis and Reduction of Surface Damage in Silicon Following Hydrogen Passivation.
Authors: GREGORY J. A. , VAYMAN Z. Y. , HANOKA J. I.
Published: May 2016

Treatment of polycrystalline Si with a hydrogen ion beam (Kaufman‐type source) is found to improve the electronic properties, but also to create a certain degree of surface damage which is quantified by near UV reflectivity and RBS measurements.
ChemInform Abstract: Dielectric Behavior of Hot‐Pressed AlN Ceramic: Effect of CaO Additive.
Authors: ZULFEQUAR M. , KUMAR A.
Published: May 2016

For all AlN samples studied (0, 0.5, 3.0, and 7.0 mol% CaO), it is found that the dielectric constant and dissipation factor increase appreciably at higher temp. (> 450 K), the increase being more pronounced at lower frequencies.
ChemInform Abstract: A Modified Benesi Titration Procedure Useful to Quantify the Lewis and Bronsted Sites of Solid Acids.
Authors: MURRELL L. L. , DISPENZIERE N. C. JUN.
Published: May 2016

Modification of the Benesi titration method by employing dry box procedures coupled with ultrasonic treatment provides a procedure where the acid site strength distribution from ≤ ‐3.0 to ≤ ‐8.2 H0 strength can be determined using a single 1 g sample.
ChemInform Abstract: IR Spectroscopy and Redox Studies of Coexchanged Europium and Iron in Y‐Zeolite.
Authors: ULLA M. A. , APARICIO L. A. , DUMESIC J. A. , MILLMAN W. S.
Published: May 2016

Studies of the reversibility, catalytic activity, and cation locations in Eu‐Y‐ and EuFe‐Y‐zeolites involve IR analysis of the chemisorption of NO together with microbalance characterization of the redox half‐reactions where oxidation and reduction are carried out in O2 and H2, or CO, respectively.
ChemInform Abstract: Podand Ionophores. A New Class of Nonmacrocyclic Yet Preorganized Hosts for Cations.
Authors: IIMORI T. , STILL W. C. , RHEINGOLD A. L. , STALEY D. L.
Published: May 2016

Starting from cis‐allylic alcohol (I), the podands (III) and (IV) are synthesized, with enantioselective epoxidations and stereoselective olefin formations as key steps.
ChemInform Abstract: Photochemistry of the Conjugated Nitrogen‐Carbonyl Systems. Part 7. Photoaddition of 2‐Pyridones to Conjugated Dienes.
Authors: SATO E. , IKEDA Y. , KANAOKA Y.
Published: May 2016

Diels‐Alder reaction of the 2‐pyridones (I) with cyclopentadiene (II) under irradiation gives a mixture of the tricyclic adducts (III) and (IV).
ChemInform Abstract: 1,3‐Dipolar Cycloadditions of Diazoalkanes to Heteroaromatic Systems. The Synthesis of Triazolo(4,3‐b)(1,2)diazepine and Cyclopropa(e)pyrazolo(4,3‐c)azolo(1,5‐a)pyridine Derivatives.
Authors: STANOVNIK B. , HABJAN G. , TISLER M. , GOLIC L. , LEBAN I.
Published: May 2016

Coupling of the methyl(phenylsulfonyl)triazolopyridazine (Id) with 2‐diazopropane (III) results in carbene insertion to give the triazolodiazepine (IV).
ChemInform Abstract: The Mechanism of the Thermal Decomposition of the Isoxazole Ring.
Authors: CORANA F. , CORSICO CODA A. , DESIMONI G. , RIGHETTI P. , TACCONI G.
Published: May 2016

The thermal decomposition of isoxazoles (I) is studied in the presence of either ethene (II) or diester (V).
ChemInform Abstract: Functionalization of Nitrogen‐ and Oxygen‐Containing Heterocycles by Mercury‐Photosensitized Dehydrodimerizations.
Authors: FERGUSON R. R. , BOOJAMRA C. G. , BROWN S. H. , CRABTREE R. H.
Published: May 2016

Mercury‐sensitized photolysis of pyrrolidine (Ia) and piperidine (Ib) in the vapour phase yields the dimers (II).
ChemInform Abstract: Photolysis of Triphenylmethylphosphonic Acid and Its Dimethyl Esters: A Novel Photochemical Generation of Dimethoxyphosphoryl(phenyl)carbene by α,α‐Elimination of Phenyl Groups.
Authors: MIN S. , OKAMOTO Y. , TAKAMUKU S.
Published: May 2016

Photolytic cleavage of the triphenylmethylphosphonic acid (Ia) or the dimethyl ester (Ib) gives biphenyl (III) and dimethyl 1‐ethoxybenzylphosphonate (IVb).
ChemInform Abstract: Sulfonomercuriation Route to Vinyl and Ethynyl Sulfones.
Authors: RAJAKUMAR P. , KANNAN A.
Published: May 2016

Addition of the sodium benzenesulfinates (II) and mercury(II) chloride (III) to the acetylenes (I) yields the organomercury compounds (IV) which are demetalated to form the alkynyl sulfones (V) or the vinyl sulfones (VIII) depending on the conditions.
ChemInform Abstract: Antifertility Agents. Part 45. Synthesis and Activity of 1,2‐cis‐1‐(p‐(β‐Pyrrolidinoethoxy)phenyl)‐2‐phenyl‐5‐methoxyindan.
Authors: MALIK M. S. , RASTOGI S. N. , SINGH M. M. , SREENIVASULU S. , AGNIHOTRI A. , KALRA V. , KABOJ V. P.
Published: May 2016

The title compound (V) shows an antifertility activity similar to that of its trans isomer.
ChemInform Abstract: Intermolecular Trapping by Indole of a Spiroindolenine Intermediate Formed During the Bischler‐Napieralski Cyclization of N‐Acetyltryptamine.
Authors: FROST J. R. , GAUDILLIERE B. R. P. , KAUFFMANN E. , LOYAUX D. , NORMAND N. , PETRY G. , POIRIER P. , WENKERT E. , WICK A. E.
Published: May 2016

Reaction of N‐acetyltryptamine (I) with indole (II) results in the formation of the spiroindolines (III) as the main products.
ChemInform Abstract: Reactions of Unsaturated Azides. Part 6. Synthesis of 1,2,3‐Triazoles from Propargyl Azides by Rearrangement of the Azido Group. ‐ Indication of Short‐Lived Allenyl Azides and Triazafulvenes.
Authors: BANERT K.
Published: May 2016

Propargyl azides derived from tosylates such as (I), (VIII) or (XII) can be converted by a one‐pot procedure into the triazoles (VII), (XI) or (XIII).
ChemInform Abstract: A Three‐Step Pyridoanellation of Carbonyl Compounds.
Authors: CHELUCCI G. , GLADIALI S. , MARCHETTI M.
Published: May 2016

The N,N‐dimethylhydrazones (III) are coupled with the bromoethyldioxolane (IV) to give the substitution products (V) which are cyclized upon heating in acetic acid to yield the pyridines (VI) as the main products.
ChemInform Abstract: Synthesis of 6,7‐Dimethoxypyrimido(4,5‐b)indoles as Potential Antihypertensive Agents.
Authors: VENUGOPALAN B. , DESAI P. D. , DE SOUZA N. J.
Published: May 2016

Starting with the 2‐aminoindole‐3‐carboxylate (I), various cyclocondensation and subsequent reactions are performed, yielding fused pyrimidones, e.g. (VII), (XIV), and (XVI).
ChemInform Abstract: Synthesis of Thiazolo(3,2‐a)thieno(2,3‐d)pyrimidines and of Structure‐Analogous 1,3‐Thiazino Compounds Starting from Ethyl 2‐Hydroxyalkylthioureidothiophene‐3‐carboxylates.
Authors: LEISTNER S. , GUETSCHOW M. + , WAGNER G.
Published: May 2016

The isothiocyanates (I) react with the amino alcohols (II) to give the thioureas (III).
ChemInform Abstract: Electron‐Rich Olefins. Part 4. Electron‐Rich Compounds with Thiophosphinamide, Carboxamide, O‐Silylurethane, and O‐Silylisourea Functionality. Synthesis, Spectroscopy, Chemical, and Electrochemical Reactivity.
Authors: BESSENBACHER C. , KAIM W. , STAHL T.
Published: May 2016

The N,N'‐disubstituted 1,4‐dihydropyrazines (I), (V), and (VIII) are prepared ((X) according to the literature).
ChemInform Abstract: Oxygen Heterocycles by Sulfur Ylide Annulation. Part 10. 3‐Hydroxy‐3,4,5,6‐tetrahydro‐2H‐1‐benzoxocins from 2‐(4‐Oxoalkyl)phenols and Dimethylsulfoxonium Methylide.
Authors: ARNONE A. , BERNARDI R. , BRAVO P. , FRIGERIO M. , TICOZZI C.
Published: May 2016

The ketones (III) react with the sulfoxonium ylide (IV) (generated from Me3SO+I‐ and NaH) to yield the fairly stable epoxides (V).
ChemInform Abstract: Nucleotide Base Recognition: A Macrocyclic Receptor for Adenine Employing Hydrogen Bonding and Aromatic Stacking Interactions.
Authors: GOSWAMI S. , HAMILTON A. D. , VAN ENGEN D.
Published: May 2016

Reductive dimerization and deprotection of (I) affords diamine (II) which is coupled (high dilution) with diacid chlorides (III) to give the macrocyclic receptors (IV) (X‐ray structures given).
ChemInform Abstract: Thermal Cleavage and Isomerization of 1,3‐Diboretanes to Stable Methyleneboranes.
Authors: PILZ M. , STADLER M. , HUNOLD R. , ALLWOHN J. , MASSA W. , BERNDT A.
Published: May 2016

By melting the 1,3‐diboretanes (IV), prepared according to the scheme, the methyleneboranes (V) and (VI) are obtained.
ChemInform Abstract: Unexpected Reactions of Decamethylsilicocene with π‐Systems of the Type X=C=Y.
Authors: JUTZI P. , MOEHRKE A. +
Published: May 2016

Via intermediate siliranes, formed by (2 + 1)cycloaddition, the products (III), (V), and (VII) and (VIII) are obtained.
ChemInform Abstract: Thermal and Photochemical Reactivity of Group VI Open‐Mode Bimetallic Complexes Based on a Binucleating Hexaphosphine Ligand System. Crystallographic Characterization of a Novel Ditungsten Heptacarbonyl Pentaphosphine Compound.
Authors: SAUM S. E. , FRONCZEK F. R. , LANEMAN S. A. , STANLEY G. G.
Published: May 2016

The thermal and photochemical reactivities of the isomorphous title complexes (I) previously prepared from M(CO)6 and the hexaphosphine are reported.
ChemInform Abstract: Metal Complexes of α‐Hydroxyimino Phosphonic Acid Derivatives. Separation of the E and Z Isomers by Metal Chelation and the Preparation and Characterization of Copper Bis((E)‐(α‐(hydroxyimino)benzyl)phosphonate)‐Water.
Authors: GIBSON D. , KARAMAN R.
Published: May 2016

The recently prepared sodium methyl (α‐(hydroxyimino)benzyl)phosphonate (I) is obtained as a mixture of Z and E isomers.
ChemInform Abstract: Periodic Trends and Ligand Effects on the Substitution Labilities of Tetrametal Cluster Complexes of the Cobalt Triad. Molecular Structure of Rh4(CO)8(HC(P(C6H5)2)3)(P(OC2H5)3).
Authors: KENNEDY J. R. , SELZ P. , RHEINGOLD A. L. , TROGLER W. C. , BASOLO F.
Published: May 2016

The substitution kinetics of the clusters (I), (IV), and (VII) with a variety of P donor ligands is explored.
ChemInform Abstract: Chain Complexes with Eleven Metal Atoms.
Authors: DAVIES S. J. , HOWARD J. A. K. , MUSGROVE R. J. , STONE F. G. A.
Published: May 2016

The stepwise synthesis of the undecanuclear PtWMo complex (VIIa) is achieved starting with the sevennuclear compound (III) containing terminal Pt(cod) groups as demonstrated in the scheme.
ChemInform Abstract: Synthesis of 1‐Substituted Derivatives of Codeine from 1‐Bromocodeine via Palladium‐Catalyzed Coupling Reactions.
Authors: DAVIES S. G. , PYATT D.
Published: May 2016

Codeine (Ia) is converted into 1‐bromocodeine (Ib) via its hydrobromide.
ChemInform Abstract: 1,1‐Difluoroalkyl Glucosides: A New Class of Enzyme‐Activated Irreversible Inhibitors of α‐Glucosidases.
Authors: HALAZY S. , DANZIN C. , EHRHARD A. , GERHART F.
Published: May 2016

The stable α‐anomer (IIIa) (half‐life 680 h in water) is isolated in pure form as a mixture of two epimers from (III).
ChemInform Abstract: Desulfation and Rearrangement of Tigemonam to an Isoxazolidin‐5‐one and the Synthesis of the Rearrangement Product.
Authors: SINGH J. , KISSICK T. P. , FOX R. , KOCY O. , MUELLER R. H.
Published: May 2016

Tigemonam (Ia) (R: ‐H) and its ester (Ia) (R: ‐CHPh2) undergo desulfation to N‐hydroxyazetidinones (Ib) which rearrange to (II).
ChemInform Abstract: Studies on the Total Synthesis of 6‐Amido‐1‐methylcarbapenems.
Authors: GREENLEE M. L. , DININNO F. P. , SALZMANN T. N.
Published: May 2016

The aldehyde (I) reacts with p‐anisidine (II) to give the corresponding aldimine which undergoes cyclocondensation with phthalimidoacetyl chloride (III), forming an inseparable mixture of the β‐lactams (IV).
ChemInform Abstract: Antioxidative Admixtures Prepared from Aromatic Amines.
Authors: ZEINALOVA G. A. , GADIROV A. A. , KYAZIM‐ZADE A. K.
Published: May 2016

Starting from the N‐benzylidene derivatives (I) or (IV) the arylaminoketones (III), the benzylarylamines (V) and the ethers (VII) are prepared.
ChemInform Abstract: Synthesis of Macrocyclic Trichothecene Mycotoxins
Authors: TAMM C. , JEKER N.
Published: May 2016

Review: (92 refs.
Phospholipid: diacylglycerol acyltransferase contributes to the conversion of membrane lipids into triacylglycerol in Myrmecia incisa during the nitrogen starvation stress
Authors: Liu Xiao-Yu , Ouyang Long-Ling , Zhou Zhi-Gang
Published: May 2016

In addition to the Kennedy pathway forde novobiosynthesis, triacylglycerol (TAG), the most important stock for microalgae-based biodiesel production, can be synthesized by phospholipid: diacylglycerol acyltransferase (PDAT) that transfers an acyl group from phospholipids (PLs) to diacylglycerol (DAG). This study presents a novel gene that encodes PDAT from the green microalgaMyrmecia incisaReisigl H4301 (designatedMiPDAT ). MiPDAT is localized on the plasma membrane (PM) via the agroinfiltration of tobacco leaves with a green fluorescent protein-fused construct. MiPDAT synthesizes TAG based on functional complementary experiments in the mutant yeast strain H1246 and the membrane lipid phosphatidylcholine (PC) is preferentially used as substrates as revealed byin vitroenzyme activity assay. The gradually increased transcription levels ofMiPDATinM.incisaduring the cultivation under nitrogen starvation conditions is proposed to be responsible for the decrease and increase of the PC and TAG levels, respectively, as detected by liquid chromatography-mass spectrometry after 4 d of nitrogen starvation. In addition, the mechanism by which MiPDAT in this microalga uses PC to yield TAG is discussed. Accordingly, it is concluded that this PM-located PDAT contributes to the conversion of membrane lipids into TAG inM.incisaduring the nitrogen starvation stress.
Comparative Outcomes of Total Knee Arthroplasty on Physically Active and Passive Patients
Authors: Waciakowski Daniel , Urban Karel
Published: May 2016

The physical activity of the population is decreasing due to an increase in sedentary lifestyles. The aim of the study was to analyze midterm results of total knee arthroplasty according to the lifelong physical activity of the patients. We evaluated 37 patients (23 women, 14 men), with age average 70.0 years (range 53–87). We divided the patients according to lifelong physical activity. The active group included 11 patients with any history of physical activity and the passive included 26 patients with a sedentary lifestyle. No intergroup differences existed in age, gender or preoperative Knee Score. The active group had a higher postoperative Knee Score 90,5 (±5,0) compared to the passive 87,4 (±5,0). Pain after arthroplasty was experienced significantly more in the active group. Between the active 87,3 (±9,3) and passive 67,5 (±16,7) groups we measured a statistically significant difference in the improvement of Functional Score – ability to walk and climb stairs. Sedentary lifestyle affects the clinical outcomes of total knee arthroplasty. This data is demonstrating that physical activity ameliorate functional postoperative results.
Recurrent Incisional Hernia Associated with Interferon Treatment for Virus C Hepatitis: Case Report
Authors: Gherghinescu Mircea , Molnar Călin , Popa Daniel , Russu Cristian , Lazăr Alexandra , Copotoiu Constantin
Published: May 2016

Background: Hepatitis C prevalence in Romania is 3.5%. Nowadays, the treatment of this condition comprise of interferon. One of the interferon’s side effects is the reduction of collagen synthesis, substance that is necessary in the process of abdominal wall healing.

Case report: We report the case of a 56 years old female patient, admitted in our Clinic for a giant, recurrent incisional hernia. The patient’s history was eventful: a hysterectomy for uterine fibroma in 2009, incisional hernia repair in 2010, the treatment with Interferon in 2011 and 2012 for viral hepatitis C. A well represented subcutaneous tissue is observed intraoperator, a wall defect of 15 cm in diameter with a 5 mm thick muscle aponeurosis lay. We performed abdominal wall plasty by components separation technique, reinforced with a polypropylene mesh disposed on lay. Postoperative analgesia was provided by inserting a wound catheter through which Ropivacaine 0,5% was continuously injected for 72 hours. The postoperative evolution was uneventful, the patient being discharged 7 days after the surgical intervention.

Conclusions: The treatment with Interferon of hepatitis C can favor the recurrence of an incisional hernia. The Oscar Ramirez procedure seemed to be the best choice for surgical treatment of this giant incisional hernia. Postoperative analgesia can be accomplished by a wound catheter through which Ropivacaine 5% is continuously infiltrated.
Microwave-assisted decomposition of fgd gypsum in the presence of magnetite and anthracite
Authors: Ji Zhong-Hai , Guo Yu , Chen Jin , Guo Li-Na , Yang Bo , Zhang Xue-Fang , Meng Ling-Jia , Qin Li
Published: May 2016

Decomposition of flue gas desulfurization (FGD) gypsum in the presence of (10 mass %) magnetite and different mass fractions of anthracite, as a reducer, has been investigated under microwave irradiation in air atmosphere. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to characterize the decomposition residues. Both experiment results and theoretical analysis indicated that the optimum amount of anthracite added to the FGD gypsum (10 mass %) magnetite mixture was 8 mass %. Under optimum conditions, the maximum desulfurization degree after microwave treatment for 60 min at 1000°C was 93.86 %. Due to microwave heating and calcium ferrite formation, the decomposition temperature of FGD gypsum decreased to around 800°C in air atmosphere. Based on the XRD patterns and SEM images, the reaction of CaSO
Relevanz und Trivialität in der soziologischen Forschung / Relevance and Triviality in Sociological Enquiry
Authors: Baldamus Wilhelm
Published: May 2016

Although the word ‚relevance’ is increasingly used in current sociology, its meaning is uncertain. Three typical usages may be distinguished: epistemological, political and professional criteria of relevance. It can be shown that the first two usages may be reduced to the third one. We are thus faced with the question: how is it possible to identify a particular substance of social knowledge which is specifically the product of professional sociological work? The question is analysed in terms of T. KUHN’s notion of a ‚scientific paradigm’, as a result, normative patterns of institutionalized scientific praxis rather than formalized rules of procedure emerge as crucial to sociological relevance. Evidence to support this is obtained by comparing two paradigmati- cally representative textbooks, T. PARSONS’ „The Social System“ and H. ZEISEL’S „Say it with figures“. It appears that methodologically the two texts are astonishingly similar, despite the extreme difference in levels of abstraction: both are using the method of successive dichotomization in the formation of concepts. Moreover, both reveal a surprising degree of paradigmatic ‚stability’. But the stability rests on different modes of scientific praxis. The stability of theoretical concept formation derives from a standardized high level of abstraction; the stability of empirical (statistical) praxis is rooted in a standardized repertoire of selected independent variables. In each case, the standardized praxis has come about as a historical process, guided largely by pragmatic criteria of increasingly ‚successful’ attempts in grasping social reality. Thus, instead of one we have in fact two sociological paradigms which developed independently of each other. This makes the task of creating a new (and presumably more ‚relevant’) paradigm all the more difficult: to find out what should be centrally important to professional sociologists at present, „recalcitrant anomalies“ from both the theoretical and the empirical domain will have to be assimilated. This cannot be achieved if one continues to speak vaguely of „social-scientific“ relevance.
Government as Clients for Social Science Research / Regierung und Verwaltung als Klienten sozialwissenschaftlicher Forschung
Authors: Sharpe Laurence James
Published: May 2016

Sozialwissenschaftler stellen sich zunehmend die Frage, welchen Beitrag sie in Prozessen politischer Willensbildung leisten können. Einige - die Pessimisten - sind der Ansicht, daß sie diesbezüglich wenig Möglichkeiten haben; andere - die Optimisten - sind zuversichtlich, daß Einflußchancen langfristig gegeben sind.

Eine nähere Betrachtung zeigt, daß die Pessimisten den Tatsachen näher kommen: Die Agenten politischer Willensbildung erweisen sich gegenüber Informationen neuer Art vielfach als resistent und sind - mit Ausnahme der Wirtschaftler - nicht geneigt, Sozialwissenschaftler als ernstzunehmende professionelle Experten anzusehen. Sie suchen ihre Unterstützung bestenfalls zu vordergründigen, von der Sache abgehobenen Darstellungs- und Legitimationszwecken. Andererseits und zugleich hegen auch die Sozialwissenschaftler - besonders die Soziologen - ihre Vorbehalte, nicht zuletzt, weil sie das Staats- und politische Leben oft unter dem Vorzeichen elitistischer Theorien anvisieren. Dazu kommt, daß sie in Fällen, in denen sie im Zuge ihrer Forschungen auf das Geschehen tatsächlich Einfluß nehmen könnten, entscheidungsstimulierende und bündige Schlußfolgerungen, die die Politiker dann von ihnen fordern, nicht oder nur zögernd anbieten wollen.

Erfahrungen der letzten Zeit legen immerhin nahe, daß ungeachtet dieser Schwierigkeiten die Optimisten recht behalten könnten: Hochqualifizierte sozialwissenschaftliche Forschung, die die Gesellschaft bewußt auf ein neues Verständnis der Rolle des Staates hinzuorientieren vermag, dürfte am Ende in der Lage sein, den jetzt herrschenden Stil in der politischen Willensbildung zu verändern.
Offene und geschlossene Gesellschaften Überprüfung einer Hypothese im interkulturellen Vergleich: Melanesien und Polynesien / Open and Closed societies Examination of an hypothesis in intercultural comparison: Melanesia and Polynesia
Authors: Seibel Hans Dieber
Published: May 2016

Using anthropological and archaeological data on Melanesia und Polynesia, the hypothesis is being tested that societies in relatively problematic environmental situations tend toward open role allocation (i. e. role creation and competitive incumbent selection by achieved criteria) while societies under relatively unproblematic conditions tend toward closed role allocation (i. e. normation by ascribed criteria) and frequently toward rigid stratificational hierarchies.
Von sozialer Schichtung zu sozialer Ungleichheit
Authors: Bolte Karl Martin
Published: May 2016

Der Beitrag informiert über Forschungsarbeiten in den Jahren 1952-1956, aus denen u. a. die Veröffentlichung „Sozialer Aufstieg und Abstieg. Eine Untersuchung über Berufsprestige und Berufsmobilität“ hervorgegangen ist. Es wird über Impulse und Weiterwirkungen berichtet, die von diesen Arbeiten bis in die Ungleichheitsforschung der Gegenwart ausstrahlen.
Da Saúde Materno Infantil ao PAISM
Authors: RATTNER Daphne
Published: May 2016

.
Movimentos sociais e participação em contexto de conflitos socioambientais: uma proposta de matriz de análise
Authors: HOEFEL Maria da Graça Luderitz , SEVERO Denise Osório
Published: May 2016

As formas de participação e atuação dos movimentos sociais vêm passando por profundas alterações nas últimas décadas e têm acompanhado as mudanças estruturais e conjunturais da sociedade. No contexto do Brasil e do mundo, o reascenso de grandes mobilizações e demandas pela democracia evidenciam que as lutas sociais, políticas e culturais têm apresentado novos contornos, estratégias e formas de organização que necessitam reflexão. Nesse sentido, a participação social em saúde também tem transitado e seguido o fluxo da dinâmica social, revelando cada vez mais suas interfaces com o ambiente, com o modelo de desenvolvimento e com a organização da sociedade. O objetivo deste artigo é discutir uma proposta de Matriz de Análise da intensidade democrática da participação e atuação dos movimentos sociais – à luz do conceito de intensidade democrática de Boaventura de Sousa Santos – bem como debater o seu processo de construção teórica, metodológica e sua aplicabilidade. Esta matriz vem sendo construída desde 2010 (Hoefel et al, 2010) e surge primeiramente vinculada a uma pesquisa sobre as formas de participação social em saúde-trabalho-ambiente no contexto da América Latina. Posteriormente, ela é reformulada, originando uma segunda versão (Hoefel et al, 2011), construída durante o desenvolvimento de uma pesquisa realizada na região da Chapada do Apodi, estado do Ceará, cujo objetivo geral foi analisar os processos de resistência (participação) e violência no contexto de conflitos socioambientais. Os resultados sugerem que a matriz avança no sentido de expressar, em seu conjunto de categorias, o referencial adotado, sinalizando potencialidades e aplicabilidade no que tange à análise da intensidade democrática da participação e à atuação dos movimentos sociais.
Is There a School to Prison Pipeline? The Case of France
Authors: Duckworth Cheryl Lynn
Published: May 2016

In the wake of the January 2015 attacks on Charlie Hebdo, (a satirical newspaper in Paris), there was much commentary on free speech, security, intelligence and the marginalization and dispossession of some young Muslim immigrants (and children of immigrants). Analysis has seemed, reasonably, to focus on economic opportunities, as well as addressing some identity and cultural issues, such as whether or not female Muslims should be allowed to wear a headscarf. The media reported that the two young men who seem to have led the attack on Charlie Hebdo had dropped out from school, going on to work low-wage jobs such as pizza delivery. Little of the news coverage details their education beyond that they were remembered as average Parisian boys, as media coverage focused of course on live breaking events, with less in-depth analysis of the social, economic and political factors driving the broader conflict between European and North American states and their Muslim immigrant residents and citizens. The Charlie Hebdo attacks, like 9/11, were only one expression of this broader escalating and expanding conflict. The academic literature does discuss in depth the history of France’s colonization of countries such as Algeria and Morocco, as well as the racist oppression and economic marginalization Maghrebi immigrant families face—even two generations later. (Bienkowski, 2010; Bowen 2007; Cesari 2002; Franz 2007; Limage 2010; Keaton 2005; Jugé and Perez 2006; Landof and Pagan 2005; Levine 2004; Mahmood 2006; Zimmerman 2015). This paper will thus explore the question of whether there is a “school to terror” pipeline—that is, is there anything about the pedagogy, curriculum, school culture or educational policies of France which might well be contributing to the radicalization of young people? I will conclude with consideration of what peace pedagogy might be able to contribute in terms of conflict transformation.
Construction of Distance Education Classroom in Architecture Specialty Based on Internet of Things Technology
Authors: YANG Yuqiao , YU Kanhua
Published: May 2016

Internet of Things technology and industrial development will trigger a new round of information technology revolution and industrial revolution, and they are the commanding point of future competition in information industry and core driving force of industrial upgrade. This paper introduces current situation of distance teaching of Internet of Things and architecture specialties, designs and implements distance teaching experiment system platform for architecture specialty based on Internet of Things. This system is based on ZigBee /GPRS wireless network technology, sensor technology, embedded technology, Web distributed software technology and database technology. Besides, it adopts three interlinked networks and achieves efficient connection of multiple experiment terminals, servers and clients. As well, the information exchange is fast. Hence, it is convenient for practical application of distance teaching. The results of teaching experiment show that Internet of Things technology can improve students’ academic performance and teachers’ teaching effect. Therefore, it is a hot spot in modern teaching technology, so we should pay attention to it.
Time dependent seismicity along the western coast of Canada
Authors: Christou Evangelos V. , Karakaisis George , Scordilis Emmanuel
Published: May 2016

Decelerating generation of intermediate magnitude earthquakes (preshocks) in a narrow region (seismogenic region) and accelerating generation of relatively larger such earthquakes in a broader region (critical region) has been proposed as an appropriate model for intermediate-term earthquake prediction. We examined the seismic activity which preceded the Mw=7.7 (October 28, 2012) thrust event that occurred off the west coast of Haida Gwaii, Canada (formerly the Queen Charlotte islands), by applying the decelerating-accelerating seismic strain model. We found that this mainshock was preceded by a pronounced accelerating seismic sequence with the time to the mainshock, as well as by an equally easily identifiable decelerating seismic sequence. Both precursory seismic sequences occurred in different space, time and magnitude windows. The behavior of previous mainshocks that occurred close to the 2012 earthquake was also examined by the time and magnitude predictable regional model. An attempt was also made to identify such seismic strain patterns, which may also be related to the generation of strong mainshocks along the western coast of Canada.
On the seasonal variations of reflectivity and turbulence characteristics of low‐latitude mesospheric echoes over Gadanki
Authors: Selvaraj D. , Patra A. K. , Narayana Rao D.
Published: May 2016

Gadanki radar observations of the low‐latitude mesospheric echoes studied earlier have shown that while both occurrence rate and signal‐to‐noise ratio of the mesospheric echoes peak in the equinoxes turbulent kinetic energy (TKE) dissipation rate and eddy diffusivity, estimated using spectral width of these echoes, peak in the summer. This seasonal difference is apparently inconsistent with the understanding that the mesospheric echoes are generated by turbulence. In this paper, we analyze Gadanki radar observations of mesospheric echoes made during 2011 and 2012 and study seasonal variations in reflectivity and TKE dissipation rate in an attempt to address the aforementioned puzzle. We show that both reflectivity and TKE dissipation rate in the mesosphere show semiannual variations peaking in the equinoxes, which are vastly different from those reported earlier. We also show that seasonal variations in reflectivity and TKE dissipation rate have a close correspondence with gravity wave activity. These results are found to be consistent with the gravity wave breaking hypothesis generating turbulence and radar echoes in the low‐latitude mesosphere.
Insights into the formation and dynamics of coignimbrite plumes from one‐dimensional models
Authors: Engwell S. L. , de' Michieli Vitturi M. , Esposti Ongaro T. , Neri A.
Published: May 2016

Coignimbrite plumes provide a common and effective mechanism by which large volumes of fine‐grained ash are injected into the atmosphere. Nevertheless, controls on formation of these plumes as a function of eruptive conditions are still poorly constrained. Herein, two 1‐D axysymmetric steady state models were coupled, the first describing the parent pyroclastic density current and the second describing plume rise. Global sensitivity analysis is applied to investigate controls on coignimbrite plume formation and describe coignimbrite source and the maximum plume height attained. For a range of initial mass flow rates between 108 and 1010 kg/s, modeled liftoff distance (the distance at which neutral buoyancy is attained), assuming radial supercritical flow, is controlled by the initial flow radius, gas mass fraction, flow thickness, and temperature. The predicted decrease in median grain size between flow initiation and plume liftoff is negligible. Calculated initial plume vertical velocities, assuming uniform liftoff velocity over the pyroclastic density current invasion area, are much greater (several tens of m/s) than those previously used in modeling coignimbrite plumes (1 m/s). Such velocities are inconsistent with the fine grain size of particles lofted into coignimbrite plumes, highlighting an unavailability of large clasts, possibly due to particle segregation within the flow, prior to plume formation. Source radius and initial vertical velocity have the largest effect on maximum plume height, closely followed by initial temperature. Modeled plume heights are between 25 and 47 km, comparable with Plinian eruption columns, highlighting the potential of such events for distributing fine‐grained ash over significant areas.