bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisa Syariah Terhadap Konsep dan Jualan Lelong Secara Bisik: Kajian Kes Pasar Bisik Kuala Muda Kedah
Authors: Mas'ad Aunurrochim Muhamad
Published: April 2021

Auction is a sale process practiced by communities by offering goods or services for bid and selling them to the highest bidder. Normally, the auction is implemented openly, but there are some people who did it in secret in which the buyer or bidder will whisper alternately price offered to the seller and followed by the other bidders as what happened in the market mechanism in Kuala Muda Malaysia which called as Pasar Bisik. This paper aimed to examine the extent of compliance of the auction sale conducted by whisper to the Islamic law in terms of fulfillment of the principles and conditions of sale contract. The study found that selling auction by whisper is like an ordinary auction sale practice which made either bright light or in writing even in the online auction, ie when the rules and conditions can be fulfilled and independent of the main elements of which are prohibited; riba, gharar, najsy, curbun and maysir. Rather than that, Islam is very concerned and considering the good habit or practice among the society to make it as a rule based on Islamic legal maxims (al-cadat Muhakkamah) and (al-macruf curfan ka al-masyrut syartan).

Abstrak

Lelong adalah salah satu proses jual beli yang diamalkan oleh sebahagian masyarakat untuk memenuhi kehidupan mereka dengan cara menawarkan barang atau (perkhidmatan) untuk dibida, mengambil bida kemudian menjual barang kepada pembida tertinggi. Kebiasaannya lelong dilakasanakan secara terbuka sama ada secara lisan ataupun bertulis. Namun ada juga sesetengah masyarakat yang melakukannya secara bisik di mana pembeli atau pembida akan membisikkan secara bergantian harga barang yang ditawarkan kepada penjual dan dikuti oleh pembida-pembida yang lain sepertimana yang berlaku pada mekanisma pasar bisik di Kuala Muda Malaysia. Oleh itu, kertas kerja ini bertujuan untuk mengkaji sejauh mana kepatuhan jual beli lelong yang dilakukan secara bisik terhadap kehendak syarak dari segi terpenuhinya rukun dan syarat jual beli. Hasil kajian mendapati bahawa jual beli lelong secara bisik tak ubahnya seperti praktek jual beli lelong secara tradisional yang dilakukan sama ada secara terang terangan ataupun secara bertulis bahkan lelong di atas talian; iaitu boleh apabila rukun dan syaratnya terpenuhi dan bebas dari elemen utama yang dilarang; riba, gharar, najsy, curbun dan maysir. Selain itu, syarak sangat mengambil berat dan mempertimbangkan aspek kebiasaan atau amalan yang baik yang menjadi tradisi di kalangan masyarakat untuk dijadikan suatu hukum sebagaimana disebutkan dalam kaedah fiqh (al-cadat muhakkamah) dan (al-macruf curfan ka al-masyrut syartan).
Al-Muhaddithat: The Women Scholars In Islam
Authors: Hamisan@Khair Nur Saadah
Published: April 2021

The book entitled Al-Muhaddithat: The Women Scholars in Islam was written by Mohammad Akram Nadwi, and it was published by Interface Publications Ltd. in 2007. It was the result of a study of more than 15 years to produce 40 volumes of Muslim biographies of the women scholars of hadiths which were written in Arabic, and this book is an early introduction which was written in English. The author has explained in the pre-book as an introduction regarding the purpose of writing this book. It contains ten chapters. Each chapter is equipped with footnotes, and the list of references consists of classical sources (turāth) and Arabic manuscripts arranged alphabetically. Although this book is a preamble to the wider series of books, it was a great effort and has received a very positive response among readers. It is reasonable as compulsory reading material by the academicians and students who are directly involved in the field of Hadith, but it is also not too heavy to be used as general reading for the public who are keen to explore the culture of knowledge practiced by women who are known as al-muḥaddithāt.

Abstrak

Buku yang berjudul Al-Muhaddithat: The Women Scholars in Islam aditulis oleh Mohammad Akram Nadwi, dan telah diterbitkan oleh Interface Publications Ltd. pada tahun 2007. Ia adalah hasil kajian selama lebih daripada 15 tahun untuk menghasilkan 40 jilid kamus biografi ulama wanita hadis Nabi yang ditulis dalam bahasa Arab, dan buku ini merupakan pengenalan awal kepada kamus tersebut yang ditulis dalam bahasa Inggeris. Hal ini dijelaskan di dalam pra kata buku sebagai pengenalan kepada tujuan buku ini ditulis. Ia mengandungi sepuluh bab. Dimulai dengan “Pendahuluan” sebelum bab pertama, dan diakhiri dengan “Rujukan” dan “Indeks”. Setiap bab dilengkapi dengan nota kaki, dan senarai rujukannya terdiri daripada sumber klasik (turāth) dan manuskrip Arab yang disusun mengikut abjad. Biarpun buku ini merupakan mukaddimah kepada siri buku yang lebih luas, ia merupakan usaha yang sangat besar dan telah pun mendapat respon yang sangat positif dalam kalangan pembaca. Ia wajar dijadikan bacaan wajib oleh para akademik dan pelajar yang terlibat secara langsung dalam bidang hadis, tetapi ia juga tidak begitu berat untuk dijadikan bacaan umum untuk orang awam yang berminat untuk mendalami budaya ilmu yang telah dipraktikkan oleh para wanita yang bergelar al-muḥaddithāt.
STUDENT RESEARCH: ACQUIRING KNOWLEDGE ABOUT THE NATURE AND PROCESS OF SCIENCE
Authors: Lakhvich Todar
Published: April 2021

In April of 2017, I was working with the team of FEBS (Federation of European Biochemical Societies) Education Ambassadors from different European countries and Education Committee members in Université Paris Descartes. This was a significant event, involving FEBS Constituent Societies, to create a platform at the Europen level to brainstorm on educational issues across Europe. The discussions focused on what would be done in order to meet the mission and vision of FEBS on educational issues ̶ to promote education throughout Europe. Along with the other very important issues (curriculum, inventory of key skills, good practice, etc.) the working group on learning resources has elaborated short and long term objectives to formation of an appropriate learning database in the field of Biochemistry and Molecular Biology education. The participants discussed a lot about the importance of inquiry based approach which includes in particular the conduction, evaluation and presentation of Student Research.
VALIDATION OF THEORETICAL CONSTRUCTS TOWARD SUITABILITY OF EDUCATIONAL SOFTWARE FOR CHEMISTRY EDUCATION: DIFFERENCES BETWEEN USERS AND NONUSERS
Authors: Chroustová Kateřina , Bílek Martin , Šorgo Andrej
Published: April 2021

The aim of this research was to empirically validate constructs for evaluation of teachers' attitudes toward usage of educational software in chemistry teaching. Questionnaire with items transformed from UTAUT (Unified theory of acceptance and use of technology) and other technology acceptance theories were filled in by 556 Czech chemistry teachers. All constructs passed recommended .7 thresholds of Cronbach’s alpha so they can be used in acceptability researches before and after introduction of educational software or building models. However, analyses of effect sizes show that there are not only differences between users and all nonusers generally, but also prove differences between various types of nonusers. Nonusers were established as a) those who had used educational software and abandoned it; b) those who do not use educational software, but are planning to use it in the future, and c) those who do not use educational software and have no intentions to use it. An unexpected finding reveals that differences among subgroups of nonusers can be even larger than between users and nonusers, especially the group c) is an outstanding group. Consequently, factors and their influence on the acceptance and use of educational software in chemistry teaching should be explored for each group separately. Keywords: chemistry education, education software, technology acceptance.
UNPACKING THE SOUTH AFRICAN PHYSICS-EXAMINATION QUESTIONS ACCORDING TO BLOOMS’ REVISED TAXONOMY
Authors: Motlhabane Abraham
Published: April 2021

The quality and standard of South African examination questions for the grade 12 examination have become an important issue for the South African education system. So far, the focus of empirical research has been on factors that lead to poor performance in the Physical sciences as well as the alignment of the grade 12 Physical Sciences examination with the core curriculum in South Africa. On the contrary, this research paper focuses on a different aspect: the weaknesses and the strengths of the Physics examination questions. It addresses the question of how the Physics examination questions cover higher and lower order level questions in the Bloom’s revised taxonomy. To answer this question, the Physics examination questions of the year 2014 and 2015 were analysed using Bloom’s revised taxonomy of learning objectives. The examination questions were codified and the frequencies and percentages of occurrence of different learning objectives were calculated. The results show that third level cognitive skills were more prevalent than other ones. Furthermore, examiners asked questions that require application and few questions requiring the recall of knowledge.
Keywords: physics examination, revised Bloom’s taxonomy, quality of education.
Окремі аспекти кримінологічного аналізу злочинності
Authors: Забарний М. М.
Published: April 2021

У цій статті наведено окремі аспекти кримінологічного аналізу сучасних тенденцій злочинності в Україні та посилення їх негативного впливу на криміногенну обстановку у нашій державі за соціально-економічним, воєнно-політичним та культурно-ідеологічним напрямами. Вказується, що особливо небезпечним є множення зазначених факторів один на одного, що може призвести до вкрай негативних наслідків у всіх сферах соціального життя. Відповідно, зазначені тенденції злочинних проявів мають бути обов’язково враховані під час розробки прогнозів злочинності та планування конкретних заходів кримінологічного забезпечення запобігання злочинності в Україні. Зазначено, що суттєвий вплив на стан злочинності чинять і недоліки реформування правоохоронних органів. Вказується також, що на злочинність впливають прорахунки у кадровій політиці, що спричинили відплив досвідчених працівників, зниження службової мотивації, інші недоліки реформування правоохоронних органів.
Юридическое лицо как уголовно преследуемый субъект в современном праве
Authors: Алыева Х. Р.
Published: April 2021

В статье автором была предпринята попытка осветить актуальную проблему привлечения к уголовной ответственности юридических лиц в компаративном контексте. При этом был использован ресурс зарубежного уголовного законодательства, зарубежной уголовно-правовой доктрины и теоретической базы ученых, проанализировавших данный вопрос в своих трудах.
Brain abscess complicating a diabetic man with Evans syndrome: a case report
Authors: Alam Dilruba , Habib Rumana , Muhtasim Mahir , Haque Md Rezwanul
Published: April 2021

Brain abscess is a relatively rare but potentially life threatening condition. The classic clinical triad of fever, headache and focal neurological sign may not be present in an immuno-compromised patient. The diagnostic delay may result in fatal outcome. A 52-year-old diabetic gentleman with history of chronic immunosuppressive therapy due to Evans syndrome presented with headache, generalized tonic- clonic seizure and right upper limb monoparesis. Clinical ground and neuroimaging was suggestive of pyogenic brain abscess. Patient was treated with antibiotic therapy for prolong period and there was complete clinical and radiological recovery.

Birdem Med J 2021; 11(2): 137-141
Imperforate Hymen: A Rare Cause of Abdominopelvic Mass in an Infant
Authors: Dixit Thapa Baburam , Regmi Mohan Chandra
Published: April 2021

Symptomatic imperforate hymen is very rare in infants. Here we report a neonate who presented with imperforate hymen with abdominal distension, fever and loose stool. Imaging study showed large thick walled cystic lesion extending from pelvis to abdomen upto epigastric region with bilateral mild hydroureteronephrosis and lower part in between urinary bladder and rectum suggesting hydrometrocolpos. There was spontaneous rupture leading to flow of collection. It leads to spontaneous resolution of the mass which was confirmed with pelvic ultrasound and computed tomography.Keywords: Hydrometrocolpos; hydroureteronephrosis; imperforate hymen
OPINION JOURNALISM ACTIVITY OF VOLODYMYR SALSKYI
Authors: KAMENTSEV Denys
Published: April 2021

The main directions of journalistic activity of the Major General, Minister of Military Affairs of the Ukrainian People's Republic (UPR), and the Ukrainian People's Republic in exile Volodymyr Salskyi, which became an integral part of his social and political activity, are considered. Passion for journalism was typical of many prominent personalities of the early 20th century. V. Salskyi considered opinion journalism an essential element of educational activities, and under the war conditions – an effective method of ideological influence on the people, the formation of its national consciousness and patriotism. The military-political figure's first attempts in opinion journalism occurred in 1920, stimulated by his own experience of participation in World War I and the Ukrainian National Revolution, difficult domestic and foreign policy circumstances in Ukraine, and the struggle against Bolshevik Russia. The top of his journalistic career was the emigration period, especially in the second half of the 1920s. The publications with which V. Salskyi collaborated were considered, in particular, «Tabor», «Hurtuimosia», «Tryzub», «Za Derzhavnist».

The minister's articles were united around national-state issues, the propaganda of patriotism, sincere faith in the Ukrainian cause's success, and, finally, the building of an independent united Ukraine. The central leitmotif of almost all publications is the army, the history of its formation, heroism in the national liberation struggle of 1917–1921, as well as the role in the further struggle for the realization of the national idea. V. Salskyi's articles are analyzed. His articles demonstrated the author's remarkable writing talent; his publications on military-political and military-historical topics showed in-depth knowledge of political science, theory and practice of military affairs, and international politics. V. Salskyi's opinion journalism played a significant role in popularizing the Ukrainian national idea and the development of cultural, educational, and national life of Ukrainians in exile.

Keywords: Volodymyr Salskyi, Minister of War, journalism, «Tryzub», national idea.
BCI-based games and ADHD
Authors: Bravou Vasiliki , Drigas Athanasios
Published: April 2021

Attention Deficit Hyperactivity Disorder (ADHD) is a neurological condition characterized by cognitive task difficulty, impulsivity, hyperactivity and loss of attention. It can persist into adulthood with negative academic and socio-professional outcomes. Neurofeedback treatments have been shown as effective for training the attention ability in children with ADHD. It has been found that interactive multi-player games are ideal from a therapeutic and long-term usage point of view due to their higher social motivation and cooperation among children with ADHD. In this study we conducted a semi-systematic review, with the goal of gathering findings from empirical and theoretical works in order to deepen our understanding about the use of Brain Computer Interface (BCI)-based for children and adults with ADHD, as a method to ameliorate the symptoms of their disorder.
Projeto de educação em saúde sobre Sífilis durante a pandemia de Covid-19 por meio de redes sociais: Um relato de experiência
Authors: França João Victor Coimbra , Araújo Isabel Bacelar Fontenele , Barros Luis Felipe Rodrigues Brandão de , Camboim Luiz Fernando Reis , Costa Rafael Everton Assunção Ribeiro da , Maia Filho Antônio Luiz Martins , Monte Samylla Miranda , Marques Rosemarie Brandim
Published: April 2021

Introdução: As infecções sexualmente transmissíveis (ISTs) são um importante problema de saúde pública, trazendo muitas consequências para a população mundial. A sífilis é uma IST causada pela bactéria Treponema pallidum e constitui uma importante doença no contexto da saúde brasileira pelo aumento de casos nos últimos anos. Objetivo: Descrever as ações remotas em redes sociais de um projeto de educação em saúde sobre sífilis, desenvolvido durante a pandemia de COVID-19, e analisar seus impactos na comunidade. Metodologia: O presente projeto utilizou a plataforma digital Instagram® para divulgar panfletos sobre a doença, tirar dúvidas da população alvo, além de coletar dados dos usuários da rede social sobre o tema. Resultados: Os resultados foram quantificados de acordo com as visualizações das postagens veiculadas. O panfleto inicial sobre sífilis obteve um alcance de 2513 visualizações e, nas semanas de postagem posteriores, houve os totais de 7847, 1037, 1058, 3793 e 2481 visualizações em cada tópico, respectivamente. Considerações Finais: Cabe destacar que, inicialmente, o objetivo do projeto de extensão universitária era ser presencial, tanto com a utilização de testes rápidos para detecção de sífilis como com a apresentação de palestras em uma comunidade carente de Teresina, Piauí, Brasil. No entanto, o projeto teve que ser adaptado ao meio digital devido às medidas relacionadas à pandemia de COVID-19 recomendadas por autoridades de saúde. Ainda, apesar da impossibilidade de seguir o planejamento inicial, o projeto atingiu um bom alcance, inclusive sendo divulgado nas plataformas online da Universidade Estadual do Piauí.
O papel do estresse oxidativo na Doença de Crohn: Uma revisão narrativa
Authors: Basílio Fernanda Silva , Santos Júlia Maiara dos , Branco Cátia Santos
Published: April 2021

A doença de Crohn (DC) faz parte de um conjunto de desordens inflamatórias do trato gastrointestinal de sintomatologia variada e caráter crônico. Evidências têm mostrado uma associação entre estresse oxidativo e DC. Nesse sentido, diferentes biomarcadores estão sendo estudados, porém ainda não há consenso. O objetivo deste estudo foi compilar os mais recentes estudos sobre o equilíbrio oxidante/antioxidante na DC em pacientes ativos e em remissão. Dentre os biomarcadores, os relacionados à peroxidação lipídica foram os mais estudados na DC. Observou-se que, mesmo com a doença sob controle, pacientes remissivos continuam a apresentar níveis de estresse oxidativo (danos oxidativos aos lipídeos e proteínas) altos e defesas antioxidantes (atividade de GPx e catalase) alteradas. Além disso, os níveis plasmáticos de selênio, um mineral com importante ação antioxidante, foram encontrados diminuídos nos pacientes, independentemente do estágio da doença. Esses achados demonstram a necessidade de monitorar o paciente em relação aos biomarcadores de estresse oxidativo e de defesa antioxidante, especialmente em períodos de remissão, em que o paciente não apresenta sintomas, porém mantém as alterações oxidativo-inflamatórias latentes. Os dados aqui discutidos poderão colaborar para a concepção e desenvolvimento de novas abordagens para pacientes com DC.
Assistência de enfermagem ao paciente oncológico submetido à anestesia
Authors: Cesário Jonas Magno dos Santos , Flauzino Victor Hugo de Paula , Hernandes Luana de Oliveira , Gomes Daiana Moreira , Vitorino Priscila Gramata da Silva
Published: April 2021

O objetivo deste trabalho foi descrever os riscos associados à anestesia no paciente oncológico e os cuidados de enfermagem durante anestesia no paciente oncológico. A pesquisa é uma revisão bibliográfica de abordagem descritiva e qualitativa. Foi realizada nos Bancos de dados do Google Acadêmico, BVS (biblioteca virtual em saúde) e SciELO (ScientificElectronic Library Online), com a seguinte pergunta de pesquisa: quais os cuidados de enfermagem ao paciente oncológico submetido à anestesia? Foram inclusos os artigos acadêmicos publicados entre 2012 á 2020, na língua portuguesa, disponíveis de forma gratuitos. Foram excluídos os artigos inferiores a 2012, resumos, periódicos que não contemplavam nenhum dos objetivos, que não respondessem à pergunta de pesquisa e artigos repetidos encontrados nas bases de dados citadas acima, no qual resultou em uma amostra final de 35 artigos. As complicações anestesia geral em pacientes oncológicos são o desenvolvimento de paralisia das cordas vocais após a intubação, o tempo prolongado de jejum, edema pulmonar, atelectasia, pneumonia, obstrução da VAS (vias aéreas superiores), broncoespasmo, edema de VAS, bronquite e exacerbar DPOC (Doença Pulmonar Obstrutiva Crônica), e os anestésicos utilizados podem gerar complicações como: fraqueza da musculatura faríngea, depressão respiratória, pruridos, náuseas, vômitos, retenção de urina, diminuição da motilidade gastrointestinal e obstrução intestinal paralítica. A atuação do enfermeiro nos procedimentos anestésicos é fundamental para promover um ambiente seguro e propicio para a anestesia e realizar uma assistência de enfermagem segura para ter um procedimento cirúrgico tranquilo.
LARYNGEAL TUBERCULOSIS – A NEGLECTED DISEASE THAT CAN MIMIC LARYNGEAL CARCINOMA
Authors: JAVORAC Jovan , ŽİVANOVİĆ Dejan , LOVRENSKİ Aleksandra , MİLENKOVİĆ Ana , KUKAVİCA Darinka , ILİĆ Miroslav
Published: April 2021

Laryngeal tuberculosis is a form of extra-pulmonary tuberculosis that occurs in only 1% of all tuberculosis cases, with the mortality rate of less than 2%. It can be a complication of pulmonary or some other form of extra-pulmonary tuberculosis (via bronchogenic, haematogenic or lymphagenic spread of bacilli), or the larynx can be the only organ affected after the direct invasion of Mycobacterium tuberculosis. Clinical, laryngoscopic and radiological findings of laryngeal tuberculosis tend to mimic laryngeal cancer, delaying the appropriate treatment. In this paper, we present a case of the laryngeal and pulmonary tuberculosis which was primarily diagnosed and almost treated as laryngeal carcinoma. An 84 years old Caucasian male presented with a 3-months history of hoarseness, odynophagia, dysphagia, cough with expectoration and weight loss. After the laryngoscopy and biopsy of the laryngeal ulceration, a squamous cell carcinoma was suspected. However, chest X-ray and CT scan detected pulmonary infiltrates, while the positive sputum smear for acid-fast bacilli was obtained and the sputum cultures grew Mycobacterium tuberculosis. Detailed histopathological analysis of the biopsies was in accordance with tuberculosis, and no signs of timorous tissue were found. After the end of the proposed antituberculous treatment, the patient reported no symptoms of the diseases, laryngoscopic findings showed no signs of neoplastic tissue, and CT findings showed partial radiological regression. Distinguishing laryngeal carcinoma and tuberculosis can be very challenging, even after obtaining histopathological material. Nevertheless, biopsies should be taken from all suspicious lesions and at multiple sites and Ziehl-Neelson staining of sputum and bioptic tissue is necessary. Otorhinolaryngologists should always consider tuberculosis in differential diagnosis of laryngeal lesions, especially nowadays when the incidence of laryngeal tuberculosis is increasing in developing countries.
Dendritic cells and T lymphocyte interactions in patients with lymphoid malignancies
Authors: Pytlík R , Hofman P , Kideryová L , Červinková P , Obrtlíková P , Šálková J , Trněný M , Klener P
Published: April 2021

Dendritic cell (DC) vaccination is an attractive approach to the
treatment of patients with lymphoid tumors. To evaluate its
feasibility, we have tested the functional properties of DC and
T-lymphocytes in patients with treated and untreated chronic
lymphocytic leukemia (CLL) and follicular lymphoma (FL). Healthy
volunteers were used both as controls and as a source of cells for
allogeneic mixed leukocyte reaction (MLR). In these reactions,
dendritic cells from both untreated and treated patients were
comparable to dendritic cells from healthy volunteers. In all the
untreated patients studied, autologous dendritic cells promoted
the survival and proliferation of both CD4 and CD8 lymphocytes
(though the proliferation response was much better in the CD4
subset), whereas only 3 out of 5 treated patients were able to
mount this response with CD4 lymphocytes and 4 out of 5 with
CD8 lymphocytes. In 3 out of 5 untreated patients, pulsing of
DCs with tetanus toxoid promoted a better CD4 response than
was achieved with unpulsed DCs, while none of 5 treated
patients had an additional response after pulsing with tetanus
toxoid. None of patients studied, either treated or untreated, had
a better CD8 response to pulsed DCs than to unpulsed ones.
During CD4 lymphocyte proliferation, more CD4+CD25hi
lymphocytes were generated in both treated and untreated
patients than in healthy controls. Poor proliferation of cytotoxic
cells and preferential proliferation of CD4+CD25hi T-regulatory
cells in response to self and/or foreign antigens might be one of
the mechanisms responsible for immunosuppression and
impaired tumor surveillance in patients with lymphoid
malignancies.
Cytokine profile in cases with premature elevation of progesterone serum concentrations during ovarian stimulation
Authors: Nikolettos N , Asimakopoulos B , Köster F , Schöpper B , Scultz Ch , Caglar GS , Efthimiadou A , Pagonopoulou O , Diedrich K , Al-Hasani S
Published: April 2021

The aim of this study was to investigate the concentrations of
vascular endothelial growth factor (VEGF), basic fibroblast growth
factor (bFGF), leptin, tumor necrosis factor-α, interleukin (IL)-1β
and IL-6, in cycles with a premature rise of serum progesterone.
25 intracytoplasmic sperm injection (ICSI) cycles with (Group 1)
and 25 ICSI cycles without a premature progesterone elevation
(Group 2) were included. The cut-off value of serum
progesterone on the day of human chorionic gonadotropin (hCG)
administration was 0.9 ng/ml. The indication for ICSI was male
factor infertility exclusively. On the day of hCG injection, serum
IL-6, VEGF and bFGF were significantly higher in Group 1
(7.7±24.5 pg/ml, 290.2±161.4 pg/ml and 15.7±8.2 ng/ml
respectively) than in Group 2 (1.7±0.7 pg/ml, 175.2±92.1 pg/ml,
and 9±1.6 ng/ml respectively). On the day of follicular puncture,
serum cytokine concentrations were similar in the two groups. IL6 intrafollicular concentrations were higher in Group 1
(14.7±20.7 pg/ml) than in Group 2 (9±9.3 pg/ml, p=0.031).
There were no differences regarding the ICSI outcome. Patients
with serum progesterone above 0.9 ng/ml, have elevated serum
concentrations of IL-6, VEGF, and bFGF, as well as elevated
intrafollicular concentrations of IL-6. The outcome of ICSI cycles
is not associated with premature elevation of progesterone when
the cut-off value is set at 0.9 ng/ml.
Increased diameter and enhanced myogenic response of saphenous vein induced by two-week experimental orthostasis are reversible
Authors: Raffai G , Lódi C , Illyés G , Nádasy G , Monos E
Published: April 2021

Previously, increased diameter and enhanced myogenic tone were
seen after 2-week 45º head-up (HUT2) in the rat. We studied the
reversibility and the effect of extended tilt on this phenomenon
using two experimental groups: HUT2 plus 2-week horizontal
(HUT2HOR2), and 4-week tilting (HUT4). 4-weeks in normal cages
(NC4) served as control. Diameter of saphenous vein (SV) in 2-20
mm Hg pressure range, wall and media thickness, endothelial and
smooth muscle cell densities, and cell proliferation were measured.
The diameter of SV from HUT4 was significantly larger compared
with HUT2HOR2 or NC4 within the whole pressure range both in
Krebs-Ringer (870.4±21.3 vs. 778.2±24.9 and 771.6±28.1 μm at
10 mm Hg, respectively) and in Ca2+-free solution. Myogenic and
norepinephrine-induced vascular tone, wall and media thickness
did not differ among the three groups. Endothelial cell density
decreased in HUT4 (10.7±1.2) vs. HUT2HOR2 (15.1±1.0) and NC4
(15.3±0.6), while that of smooth muscle was unchanged. No cell
proliferation marker was seen. In conclusion, both increased
diameter and enhanced myogenic tone of SV seen in HUT2 proved
to be reversible. HUT4 resulted in increased SV diameter, similarly
to HUT2, however, vascular tone was not amplified. This suggests
that a prolonged orthostatic load may readjust the function of
smooth muscle.
Espacios de interacción transfronteriza articulados por afiliación religiosa. Un acercamiento etnográfico desde la vida socio-religiosa de mujeres zapotecas evangélicas en Ensenada, Baja California
Authors: Espino Torres Donna Melissa
Published: April 2021

The purpose of this article is to analyze the conformation of cross-border interaction spaces articulated by religious affiliation, between a congregation of Zapotec evangelical women in the city of Ensenada, Baja California, Mexico, and religious organizations and evangelical churches from the state of California, United States. The methodological approach is qualitative. Ethnographic data from 2017 and 2018 are analyzed. The originality of this work lies in showing how cross-border spaces can be built by religious affiliation, which transcends ethnic identifications and links different actors, despite the current and difficult socio-political context of the Mexico-United States border.
ERİL TOPLUMDA KADIN SESLERİ: AMASYALI KADIN ŞAİRLER VE OKSİTAN’DAKİ KADIN TRUBADURLAR ÜZERİNE MUKAYESELİ BİR ÇALIŞMA
Authors: ELBASAN Zeynep
Published: April 2021

Amasya’da 15. ve 16. Yüzyıla ait tezkireler incelendiğinde önemli dört kadın şaire yer
verildiği görülmektedir: Zeynep, Nisayi, Ayşe ve Mihri Hatun. Mihri Hatun’un divanının dört
nüshasının bulunmasına rağmen bahsi geçen diğer kadın şairlerin eserlerine sadece tezkire ve
yazışmalar üzerinden ulaşabiliyoruz. Bu şairelerin tamamı erkek şairler tarafından erkek okurlar
için tasarlanmış divan edebiyatı sınırları içinde eser vermiştir. Buna benzer bir örneği on iki ve
on üçüncü yüzyılda Oksitan edebi muhitlerinde de görüyoruz. 1150-1250 yılları arasında bir
grup kadın, trobador erkeği merkeze alan kendi klasik edebiyatlarının sınırları içinde şiirler
üretmiştir.
Bu mukayeseli çalışma yukarıda belirtilen kadın yazarların eserlerinde kadınlık ve
seslerin çokluğu kavramına odaklanmaktadır. Oksitan bölgesinden (Fransa'nın güney
kesiminden) ve Amasya'dan (Anadolu'nun kuzey kesiminden) kadın yazarların kimliğini inşa
eden sosyal koşulları daha iyi anlamak ve ilerlemelerinde önemli olup olmadığını araştırmak için
inceleniyor. Ele alınan üç karşılaştırma hususu söz konusudur: birincisi, cinsiyet söylemi sorunu,
farklı konular hakkında çoklu sesler kullanarak yazmak ve bu iki durumun kadın yazarların edebi
tarzlarını ne ölçüde etkilediğidir. İkinci olarak, kadın yazarlar arasındaki mektup yazışmaları
veya şiir üzerinden ne gibi etkileşimler olduğu da bu araştırmanın konusudur. Bu çalışma,
dönemin kadın ve erkek şairleri arasındaki etkileşime de odaklanmaktadır. Her iki durumda da
kadın yazarlar, söz konusu teknikleri erkek hegemonyası sınırları içindeki edebi dünyada statü
kazanmak için bir müzakere aracı olarak kullanmışlardır.
Rancang Bangun Sistem Informasi Akuntansi Berbasis Website menggunakan Framework Laravel
Authors: Moch Zawaruddin Abdullah  , Mungki Astiningrum  , Yuri Ariaynto  , Dwi Puspitasari  , Atiqah Nurul Asri
Published: April 2021

Perjalanan UKM di Indonesia, tak terkecuali kelompok UKM Ron Tuwuh dan Prohandji tidak semudah yang dibayangkan. Salah satu kendala yang dihadapi adalah pengelolaan keuangan untuk bisnis. Pada setiap bisnis yang dilakukan memerlukan menejemen keuangan agar roda kehidupan bisnis dapat berjalan dengan baik. Fakta dilapangan, pegiat UKM masih mempunyai kesulitan dalam proses pencatatan keuangan baik dari pemasukan dan pengeluaran. Sebagian besar UKM tidak memperhatikan transaksi keluar-masuk keuangan dan tanpa perhitungan atau pencatatan yang jelas, sehingga menimbulkan ketidakstbilan keuangan yang ada pada usaha. Dari kendala keuangan yang terjadi pada pelaku usaha UKM dan minimnya pengetahuan akan keuangan. Maka penelitian ini bertujuan untuk merancang sistem informasi akuntansi berbasis website untuk UKM khususnya pada kelompok UKM Ron Tuwuh dan Prohandji. Sistem informasi ini dikembangkan menggunakan framework Laravel untuk memenuhi kebutuhan standar pengelolaan informasi keuangan sehingga pencatatan keuangan tersistem dengan baik dan meminimalisir resiko tak terkontrolnya data keuangan.
PENENTUAN NUMBER TRANSFER UNIT SISTEM FLUIDA DIETILEN GLIKOL – METANOL, DALAM EVALUASI EFISIENSI PENUKAR PANAS SHELL AND TUBE 1-1
Authors: Abdul Chalim  , Ariani  , Much.Agung Indra Iswara
Published: April 2021

Meningkatnya pencemaran lingkungan merupakan akibat penggunaan bahan kimia yang tidak ramah lingkungan. Penggunaan bahan kimia dietilen glikol dan metanol sebagai pendingin (coolant) pada mesin merupakan salah satu aplikasi yaitu blending larutan dietilen glikol dan metanol. Penelitian ini bertujuan mendapatkan data pengaruh suhu, laju alir blending larutan dietilen glikol – metanol dalam heat exchanger type shell and tube 1-1 guna didapatkan nilai terbaik dari NTU dan efektivitas alat. Didalam penelitian ini, digunakan variabel laju alir fluida dingin masuk dengan kisaran 140 – 248 L/jam. Laju alir fluida panas masuk dengan rentang 50 – 75 L/jam. Sedangkan suhu fluida panas masuk berkisar antara 34 – 45oC. Rasio mol blending dietilen glikol – metanol 1 : 1, 1 : 3, dan 3 : 1. Dari hasil penelitian didapatkan pada rasio mol 1 : 1 blending fluida dietilen glikol - metanol dengan suhu fluida dingin 34oC didapat harga terbaik NTU = 3,39 dan efektivitas = 0,94.
ALTERNATIF PENANGANAN LOSSES AKIBAT KETIDAKSEIMBANGAN BEBAN PADA TRAFO DISTRIBUSI
Authors: Anang Dasa Novfowan  , Mochammad Mieftah  , Wijaya Kusuma
Published: April 2021

The unbalanced load on distribution transformers is mostly caused of connecting new customers and changing patterns of electricity usage in the community. The impact of the unbalanced load is the emergence of a current flowing on the transformer neutral conductor that causes energy losses. Load balancing of distribution transformers is commonly done by technicians, but the implementation takes quite a long time and is repeated, sometimes up to 4-5 times to get the appropriate results. This is more due to less valid customer phase data. Customer phase verification is needed to accelerate the load balancing process in an effort to reduce losses in distribution transformers. With valid customer phase data, just one stage of load balancing can reduce losses by 1.06%.
PERBANDINGAN PENENTUAN ANTOSIANIN PADA BUNGA ROSELLA DENGAN MENGGUNAKAN UV-VIS SPEKTROMETRI DAN PENCITRAAN WARNA
Authors: Hetty Nur Handayani  , Kaliawan  , Nanang Setio Pambudi
Published: April 2021

Antosianin sebagai salah satu antioksidan banyak terdapat pada berbagai tanaman bunga dan buah. Antosianin ini berperan dalam memberikan warna merah atau ungu pada tanaman, yang salah satunya berfungsi sebagai pencegah radikal bebas. Rosella merupakan tanaman yang banyak dikonsumsi sebagai minuman seduh, mengandung antosianin yang cukup banyak. Pengujian antosianin dalam suatu sampel berdasarkan penelitian sebelumnya menggunakan spektrofotometer UV- VIS dan HPLC. Pendekatan lebih sederhana dalam pengujian antosianin sebagai senyawa yang berwarna dengan menggunakan metode kolorimetri dan pencitraan warna. Dengan membandingkan dua metode pengujian yaitu spektrofotometer UV-VIS dan pencitraan warna, pengujian antosianin baik secara kualitatif dan kuantitatif bisa lebih mudah. Dari hasil penelitian menunjukkan bahwa dengan menggunakan spektrofotometer UV-VIS, pengujian dan karakterisasi antosianin dengan menggunakan metode pH differensial mencapai nilai koefisien korelasiyang tinggi yaitu diatas 0.995. Tetapi nilai pengukuran ini memiliki nilai maksimal pada konsentrasi 800 ppm, diatas konsentrasi tersebut nilai absorbansi lebih dari 0.8 yang mana akan melebihi nilai transmitannya. Sedangkan pengujian dengan menggunakan pencitraan warna, pengukuran konsentrasi antosianin pada 400 ppm dengan koefisien korelasi maksimum sebesar 0.9936.
RASPBERRY PI SEBAGAI PEMANTAU RUANG LABORATORIUM MENGGUNAKAN METODE PEREKAMAN TERJADWAL BERBASIS DATABASE
Authors: Usman Zulhijah Muhammad  , Eko Pamuji
Published: April 2021

Practicum activities in higher education especially in State Polytechnic of Malang are generally carried out in a laboratory and based on a predetermined schedule. In the practicum activities are usually used equipment and practical materials borrowed by students from cabinets or warehouses for storage of tools and materials. In addition, in the laboratory where the practicum is carried out there are equipment and personal belongings belonging to students or teachers. From the experience that has happened, some campus-owned lab equipment and materials have been damaged and lost, or the personal property of students or teachers who have been left behind and even lost. Monitoring and recording using ordinary cameras has a disadvantage, that is, we cannot adjust the recording schedule that changes every day based on the space usage schedule. And record data is still one part or not grouped based on space usage schedule. Therefore, it is necessary to make a system that can monitor and record the process of laboratory practicum activities based on space usage schedule. In this study a system will be made using the embeded Raspberry Pi system and a camera module with MySQL as the database, this system is designed and created so that it can be used to record the laboratory practicum activities based on the space usage schedule in the database
Forskningslitteracitet – att läsa, värdera och använda forskning i praktiken
Authors: Stolpe Karin
Published: April 2021

Forskningslitteracitet är ett relativt nytt begrepp som handlar om att förstå, värdera och omsätta forskning i praktiken. Här ingår till exempel att kunna göra skillnad på originalforskning och texter som handlar om forskning och att förstå forskningens villkor. Att skolan ska bygga på vetenskaplig grund och beprövad vetenskap står i Skollagen, och för att kunna leva upp till det behövs forskningslitteracitet.
”Du förstår, men du förstår ingenting.”
Authors: Söderman Emma , Lundberg Anna
Published: April 2021

In the following article, based on two years of participatory ethnographic fieldwork with the No Border musical, as well as interviews with 16 of the musical’s 30 participants, community theatre is investigated in a context of deportability. We analyse the working process in the theatre group, in which actors with and without resident permits participated, through the concept of politics of translation. We show how inequalities due to the constant threat of deportation for several members were brought to the forefront during the work process of creating the musical. It concerned risks of detection for the undocumented participants as well difficult living conditions related to deportability (for example insecure access to livelihood, healthcare, housing etc.). The article conceptualizes various dimensions of working together in a group where participants live in unequal conditions as a politics of translation. This concept includes the work of language translation, and also captures translations of the different experiences mentioned above, and how different positions of power can be handled and understood, within a group with the ambition to work together, in this case on a theatrical performance. Our analysis shows how theatre in a context of asylum rights activism can challenge and create alternatives to the conditions of deportability, while these simultaneously condition the activism and translation. The article contributes to knowledge about mobilization in the context of vulnerability and inequality. We hope to also contribute to a development of critical social work both within and outside academia.
Biogenic Silver Nanoparticles as a Strategy in the Fight Against Multi-Resistant Salmonella enterica Isolated From Dairy Calves
Authors: Estevez María Belén , Casaux María Laura , Fraga Martín , Faccio Ricardo , Alborés Silvana
Published: April 2021

Infectious diseases are one of the most important health problems worldwide, one of the main causes being the development of multi-resistant microorganisms. Likewise, the zoonotic potential of some pathogens and their ability to transfer resistance mechanisms, reduce the therapeutic options in both humans and animals. Salmonella enterica is an important pathogen that affects a wide range of animal species and humans, being Salmonella Typhimurium one of the most frequent serotypes affecting cattle, causing enteritis, diarrhea, and septicemia. The search for alternative therapeutic approaches has gained importance since the emergence of multidrug resistance to antibiotics and periodic outbreaks of salmonellosis. In this sense, the discovery of new drugs and the development of new strategies, such as the use of nanoparticles with antimicrobial activity, are very promising. The aim of this work was the extracellular production of biogenic silver nanoparticles using fungal extracts and the evaluation of their antimicrobial activity against resistant and multi-resistant Salmonella Typhimurium strains. We here demonstrated the potential of the biogenic nanoparticles as effective bacteriostatic and bactericidal agents for use in biomedical applications. In addition, Confocal Raman Microscopy and Atomic Force Microscopy were used to advance the understanding of the antimicrobial mechanism of biogenic nanoparticles against these pathogenic strains, the results of which suggested that the nanoparticles produced damage in several bacterial cell structures.
The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism
Authors: Yang Jingxin , Zhang Yalin , Pan Yiming , Sun Can , Liu Zuwang , Liu Ning , Fu Yu , Li Xiaofeng , Li Ye , Kong Juan
Published: April 2021

Energy substrate imbalance is a major cause of cardiac dysfunction. Vitamin D/vitamin D receptor (VD/VDR) deficiency is involved in the pathogenesis of various cardiac diseases; however, the exact underlying mechanism remains unclear. The aim of this study was to investigate whether vitamin D modulates mitochondrial fatty acid oxidase via sirtuin 3 signaling to protect the myocardium. 1-Alpha-hydroxylase-defficient mice exhibited a high metabolic rate and lower myocardial contractility than wild-type mice. Sirtuin 3 upregulation was detected in high-fat diet-fed mice receiving vitamin D3 compared with that in high-fat diet-fed mice. Both sirtuin 3 blockade and knockout inhibited the VD/VDR-induced downregulation of fatty acid oxidase in myocardial mitochondria. VD/VDR suppressed fatty acid metabolism by upregulating sirtuin 3 and lowering mitochondrial fat uptake, thereby improving myocardial function and balancing energy substrates, rather than by altering fat endocytosis and exocytosis.
Prolonged Environmental Enrichment Promotes Developmental Myelination
Authors: Goldstein Evan Z. , Pertsovskaya Vera , Forbes Thomas A. , Dupree Jeffrey L. , Gallo Vittorio
Published: April 2021

Postnatal neurodevelopment is profoundly influenced by environmental experiences. Environmental enrichment is a commonly used experimental paradigm that has uncovered numerous examples of experience-dependent plasticity in health and disease. However, the role of environmental enrichment in normal development, especially glial development, is largely unexplored. Oligodendrocytes, the myelin-forming glia in the central nervous system, provide metabolic support to axons and establish efficient saltatory conduction by producing myelin. Indeed, alterations in myelin are strongly correlated with sensory, cognitive, and motor function. The timing of developmental myelination is uniquely positioned to be influenced by environmental stimuli, as peak myelination occurs postnatally and continues into adulthood. To determine if developmental myelination is impacted by environmental experience, mice were housed in an enriched environment during peak myelination through early adulthood. Using translating ribosome affinity purification, oligodendrocyte-specific RNAs were isolated from subcortical white matter at various postnatal ages. RNA-sequencing revealed that differences in the oligodendrocyte translatome were predominantly evident after prolonged and continuous environmental enrichment. These translational changes corresponded with altered oligodendrocyte lineage cell dynamics and enhanced myelination. Furthermore, consistent with increased developmental myelination, enriched mice displayed enhanced motor coordination on a beam walking task. These findings indicate that protracted environmental stimulation is sufficient to modulate developmental myelination and to promote behavioral function.
Reductive Functionalization of Amides in Synthesis and for Modification of Bioactive Compounds
Authors: Czerwiński Paweł J. , Furman Bartłomiej
Published: April 2021

In this review, applications of the amide reductive functionalization methodology for the synthesis and modification of bioactive compounds are covered. A brief summary of the different protocols is presented in the introduction, followed by the synthetic application of these in late-stage functionalization, leading to known pharmaceuticals or to their derivatives, including bioisosteres, with potential higher activity as the main axis of the article. The synthetic approach to natural products based on amide reduction is also discussed; however, this is given in a condensed form focusing on recent or as yet unexplored applications due to a number of recently published excellent reviews covering this topic. The aim of this review is to illustrate the potential of reductive functionalization of amides as an elegant and useful tool in the synthesis of bioactive compounds and inspire further work in this field.
Recent Advances on Sorting Methods of High-Throughput Droplet-Based Microfluidics in Enzyme Directed Evolution
Authors: Fu Xiaozhi , Zhang Yueying , Xu Qiang , Sun Xiaomeng , Meng Fanda
Published: April 2021

Droplet-based microfluidics has been widely applied in enzyme directed evolution (DE), in either cell or cell-free system, due to its low cost and high throughput. As the isolation principles are based on the labeled or label-free characteristics in the droplets, sorting method contributes mostly to the efficiency of the whole system. Fluorescence-activated droplet sorting (FADS) is the mostly applied labeled method but faces challenges of target enzyme scope. Label-free sorting methods show potential to greatly broaden the microfluidic application range. Here, we review the developments of droplet sorting methods through a comprehensive literature survey, including labeled detections [FADS and absorbance-activated droplet sorting (AADS)] and label-free detections [electrochemical-based droplet sorting (ECDS), mass-activated droplet sorting (MADS), Raman-activated droplet sorting (RADS), and nuclear magnetic resonance-based droplet sorting (NMR-DS)]. We highlight recent cases in the last 5 years in which novel enzymes or highly efficient variants are generated by microfluidic DE. In addition, the advantages and challenges of different sorting methods are briefly discussed to provide an outlook for future applications in enzyme DE.