bluuebunny/crossref_metadata_2025 huggingface dataset:
Peer-to-peer accommodation in the time of COVID-19: A segmentation approach from the perspective of tourist safety
Authors: Petruzzi Marina A. , Marques Catarina
Published: August 2022

This research identifies safety practices to be adopted by organizations of peer-to-peer accommodation for different segments of tourists in a pandemic context. More specifically, it identifies the profiles of tourists based on their opinions on the safety practices they expect to find when booking peer-to-peer accommodation. Results from a Multiple Correspondence Analysis (MCA) and Cluster Analysis applied to a sample of 864 prospective tourists suggest two prominent dimensions of safety practices: information and hygiene, and protection; and four types of tourist segments: concerned tourists, indifferent tourists, forewarned tourists, and confident tourists. While the concerned tourists value all safety practices most, the indifferent tourists do not require access to information about safety measures, although they do want information on the Covid-19 regulations at their destination. The forewarned tourists attach the least importance to aspects such as information and hygiene, and the greatest to the protection aspect. In contrast, the confident tourists value all information practices and safety measures but do not appreciate the protection aspects. These results will be helpful for peer-to-peer accommodation providers wishing to customize services during and after the Covid-19 period.
Circular economy and sustainable strategies in the hospitality industry: Current trends and empirical implications
Authors: Bux Christian , Amicarelli Vera
Published: August 2022

The European Union has enacted several strategies to reach sustainability and tackle climate change. Among them, the New circular economy action plan and the Farm to Fork Strategy could represent for hotels, restaurants and resorts the leverage points towards sustainable and economic development. The present research, through a systematic and critical review of the current trends in the hospitality industry in Europe, explores and investigates 62 papers published in national and international journals. It fills in the gaps related to circular economy, farm to fork and sustainable resource and waste management empirical practices in the hospitality industry. It emerges that food waste, water and energy consumption have been the most topical concerns from 2011 to 2021, whereas ecosystems protection, rural and urban development need more care. As a common thread, consumers’ and operators’ awareness helps in translating economic into environmental benefits, whereas the development of life cycle inventory databases and dashboards to guide tourism must be implemented without delay.
‘I want every minute to be worthwhile now’: The views and experiences of people living with dementia and their care partners about returning to in-person group meetings after COVID-19 lockdown restrictions
Authors: Kelly Siobhán , Bushell Sophie , Innes Anthea
Published: August 2022

COVID-19 and the resulting limitations on freedom of movement has been difficult for many, including individuals living with dementia and those who provide support and care. In the summer of 2021, England’s national lockdown measures eased, and regulations were amended to allow indoor social gatherings. With this enabling a return to in-person meetings, this study explored the experiences of people living with dementia and current and former care partners who had previously attended groups at Salford Institute for Dementia (UK). Two phases of research were conducted. In the first phase, during the summer of 2020, telephone interviews were utilised to ask participants ( n = 13) about their views of re-engagement and how the in-person groups might be best reintroduced. Phase two began in the summer of 2021, where mood questionnaires ( n = 10) were administered and observations conducted to explore how participants experienced the return to in-person meetings. Thematic analysis resulted in the construction of three overarching themes: planning for and the reality of transitioning; safety versus autonomy; and tensions and complexities of life in the ‘new normal’. Despite initial concerns about their reintegration into the community, participants all enjoyed resuming in-person meetings. An inclusive and consultative approach to re-engagement allowed all participants to feel valued, safe, and informed about their return to campus. However, individuals living with dementia and care partners experienced the transition to re-engagement in different ways and their perceptions shifted over time. We therefore highlight the complexities of responding to different perceptions of risk and safety, while also promoting engagement and inclusivity after a period of social isolation. In this paper, we consider implications for the re-integration of individuals with dementia and their care partners into in-person social groups and propose further avenues for research.
Use of Covered Stents in Cannulation Sites as a Last Option to Salvage Failing Vascular Access
Authors: Drouven Johannes W. , Bruin Cor de , van Roon, PhD Arie M. , Ozyilmaz Akin , Oldenziel Job , Bokkers Reinoud P. H. , Zeebregts Clark J.
Published: August 2022

Purpose:

Controversy exists regarding the treatment of recurrent stenosis in vascular access at cannulation sites with a covered stent as repeated cannulation may damage the stent. The purpose of this study was to review covered stent placement at cannulation sites to salvage failing vascular access.

Materials and methods:

A total of 11 patients were included for the purpose of this study. Eight patients (72.7%) received a covered stent due to recurrent stenosis, 2 (18.2%) due to an acute occlusion, and in 1 case (9.1%), the covered stent was used to repair a damaged polytetrafluoroethylene arteriovenous graft (PTFE AVG).

Results:

Primary patency after stent placement was 40.9% at 6 months, primary-assisted patency was 79.5% at 12 months, and secondary patency was 80% at 24 months. No significant problems were observed during the dialysis sessions after stent placement. The intervention rate per patient-year was not significantly different before or after covered stent placement, at 3.8 (IQR=9.5) interventions per year versus 2.5 (IQR=3.0) interventions per year (p=0.280).

Conclusion:

In conclusion, treating failing vascular access with problems at cannulation sites with covered stents can be considered.

Clinical Impact

Treating vascular access stenosis at cannulation sites with covered stents can successfully prolong vascular access life.
Comparing the Benefit of Duplex Ultrasound Surveillance Following Both Infrainguinal Bypass Surgery and Stenting for Femoro-Popliteal Disease
Authors: Dar Than , Li Lanxin , Basra Melvinder , Crockett Stephen , Chowdhury Mohammed M , Zielinski Lukasz Piotr , Ambler Graeme K , Coughlin Patrick A
Published: August 2022

Objective

Duplex ultrasound surveillance (DUS) is commonly used following infrainguinal vein bypass. The role of DUS following endovascular revascularisation is as yet unclear. This study focuses on the role of DUS in a contemporary group of patients undergoing infrainguinal bypass or stent insertion.

Methods

All patients undergoing either an infrainguinal vein graft bypass or stent insertion into the femoro-popliteal segment (November 2014 - January 2017) were identified. Patients were followed up for 2 years. Data on entry into DUS, pre-operative characteristics, adjunctive pharmacotherapy and reintervention were collated. The primary outcomes were major lower limb amputation and mortality at 2 years post revascularisation.

Results

One hundred and thirty-five patients underwent infrainguinal vein bypass and 100 patients underwent stent insertion. 107 patients in the bypass cohort and 58 patients in the stent cohort entered DUS. For the bypass cohort, entering DUS was associated with a lower mortality rate ( P = .003) but was not associated with an improvement in amputation rates. The odds ratio of major amputation or mortality was greater in the no surveillance group (4.58, 95% CI: 1.855 – 11.364). In the stent cohort, DUS was not associated with a significant improvement in either major amputation or death (odds ratio 2.13 (95% CI 0.903 – 5.051; P = .081).

Conclusion

DUS was associated with improved survival rates in patients undergoing lower limb bypass but had no benefit in those patients undergoing stent insertion. The role of DUS following stent insertion in the femoropopliteal segment needs to be better defined.
Crack fault diagnosis of vibration exciter rolling bearing based on genetic algorithm–optimized Morlet wavelet filter and empirical mode decomposition
Authors: Han Xiaoming , Xu Jin , Song Songnan , Zhou Jiawei
Published: August 2022

The fault diagnosis of vibration exciter rolling bearing is of great significance to maintain the stability of vibration equipment. When the crack fault of the bearing occurs, the effective fault feature information cannot be extracted because the fault feature information of vibration signal is interfered by the noise around the vibrator. To solve this problem, a fault feature recognition method based on genetic algorithm–optimized Morlet wavelet filter and empirical mode decomposition is proposed. The Morlet wavelet filter optimized by genetic algorithm was used to filter the vibration signal, and then the empirical mode decomposition was applied to the filtered signal. In the envelope spectrum of the reconstructed signal, the characteristic frequency of the rolling bearing crack fault of the vibration exciter could be found accurately. Through simulation and experiment, it is proved that this method can provide theoretical and technical support for the crack fault diagnosis of vibration exciter rolling bearing.
Profiles of Burnout and Response to the COVID-19 Pandemic Among General Surgery Residents at a Large Academic Training Program
Authors: Nguyen May-Anh , Castelo Matthew , Greene Brittany , Lu Justin , Brar Savtaj , Reel Emma , Cil Tulin D.
Published: August 2022

Background

COVID-19 has placed demands on General Surgery residents, who are already at high risk of burnout. This study examined the pandemic’s impact on burnout and wellness among General Surgery residents at a large training program.

Methods

General Surgery residents at our institution completed a survey focused on self-reported burnout, mental health, perceptions of wellness resources, and changes in activities during the pandemic. Burnout was measured using the Maslach Burnout Inventory (MBI). Unsupervised machine learning ( k-means clustering) was used to identify profiles of burnout and comparisons between profiles were made.

Results

Of 82 eligible residents, 51 completed the survey (62% response rate). During COVID-19, 63% of residents had self-described burnout, 43% had depression, 18% acknowledged binge drinking/drug use, and 8% had anxiety. There were no significant differences from pre-pandemic levels ( p all >.05). Few residents perceived available wellness resources as effective (6%). Based on MBI scores, the clustering analysis identified three clusters, characterized as “overextended”, “engaged”, and “ineffective”. Engaged residents had the least concerning MBI scores and were significantly more likely to exercise, retain social contact during the pandemic, and had less self-reported anxiety or depression. Research residents were overrepresented in the ineffective cluster (46%), which had high rates of self-reported burnout (77%) and was characterized by the lowest personal accomplishment scores. Rates of self-reported burnout for overextended and engaged residents were 73% and 48%, respectively.

Conclusion

Surgical residents have high rates of self-reported burnout and depression during the COVID-19 pandemic. Clusters of burnout may offer targets for individualized intervention.
The INFINITE Study: Pilot Research Exploring Plant-Based Nutrition in Treatment for Substance Use Disorders
Authors: Kemp Tara , Lopez Nanette V. , Ward Shaun , Sherzai Dean , Sherzai Ayesha , Sutliffe Jay
Published: August 2022

Standard treatment for substance use disorders (SUDs) rarely incorporates a dietary intervention. The purpose of this research is to explore how nutrition might influence early recovery outcomes. Participants (N = 33) self-selected into the 10-week treatment (whole food, plant-based diet) or control group (standard treatment center diet). Both received weekly nutrition education lessons to complement the diet. At baseline, week 3, and week 10, participants completed assessments to track mental health markers. Mean values were calculated for Healthy Eating Index-2015 (HEI-2015) and Plant-based Diet Indices (PDI). Semi-structured interviews were gathered and analyzed using grounded theory. The intervention group had significantly higher scores for HEI-2015 and PDI scores (all P’s < .001). For all psychosocial outcomes, there was a statistically significant effect of time ( P’s < .001-.02), but not by condition. A significant condition by time interaction was seen with the Rosenberg Self-Esteem outcome ( P = .043). Resilience at 10-weeks was significantly higher in the high PDI group ( P = .031). Qualitative data showed that all participants found meaning and value in the experience. Early addiction treatment outcomes show modest but important effects of whole food plant-based nutrition and suggest value in further exploration of its use in SUD treatment.
Successful Recruitment to Qualitative Research: A Critical Reflection
Authors: Negrin Kelly A. , Slaughter Susan E. , Dahlke Sherry , Olson Joanne
Published: August 2022

Recruitment to qualitative research is an important methodological consideration. However, the process of recruitment is under-communicated in qualitative research articles and methods textbooks. A robust recruitment plan enhances trustworthiness and overall research success. Although recruitment has recently received increased attention in the qualitative methodology literature, a more nuanced understanding is required. We realized successful recruitment to our focused ethnographic inquiry. Numerous nurse educators, researchers, and administrators volunteered within three months of study initiation. Using Gibbs’ Reflective Cycle, we conducted a critical reflection on the recruitment log and participant interview data to surface factors contributing to our success. This article offers our insights into the facilitators of successful recruitment. Our reflection revealed four themes contributing to successful enrollment: (a) laying the groundwork, (b) recruitment plan, (c) building rapport, and (d) participant motivations. Two new recruitment strategies accounted for over 60% of our sample. Reporting on successful strategies for recruiting participants to qualitative research and specifying participants’ motivations to volunteer, from their perspective, make important contributions to the recruitment literature. Our article offers guidance to qualitative researchers pursuing successful recruitment. Additional research is required to evaluate the relative influence of various recruitment strategies.
An update on polycystic ovary syndrome: A review of the current state of knowledge in diagnosis, genetic etiology, and emerging treatment options
Authors: Islam Hiya , Masud Jaasia , Islam Yushe Nazrul , Haque Fahim Kabir Monjurul
Published: August 2022

Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age, which is still incurable. However, the symptoms can be successfully managed with proper medication and lifestyle interventions. Despite its prevalence, little is known about its etiology. In this review article, the up-to-date diagnostic features and parameters recommended on the grounds of evidence-based data and different guidelines are explored. The ambiguity and insufficiency of data when diagnosing adolescent women have been put under special focus. We look at some of the most recent research done to establish relationships between different gene polymorphisms with polycystic ovary syndrome in various populations along with the underestimated impact of environmental factors like endocrine-disrupting chemicals on the reproductive health of these women. Furthermore, the article concludes with existing treatments options and the scopes for advancement in the near future. Various therapies have been considered as potential treatment through multiple randomized controlled studies, and clinical trials conducted over the years are described in this article. Standard therapies ranging from metformin to newly found alternatives based on vitamin D and gut microbiota could shine some light and guidance toward a permanent cure for this female reproductive health issue in the future.
Safety and efficacy of remote ischemic conditioning combined with endovascular thrombectomy for acute ischemic stroke due to large vessel occlusion of anterior circulation: A multicenter, randomized, parallel-controlled clinical trial (SERIC-EVT): Study protocol
Authors: Guo Zhen-Ni , Abuduxukuer Reziya , Zhang Peng , Wang Chao , Yang Yi
Published: August 2022

Rationale/Aim:

Many patients undergoing successful recanalization after endovascular thrombectomy (EVT) do not have a good outcome; additional neuroprotection might benefit this group. Remote ischemic conditioning (RIC) stimulates endogenous protective mechanisms and may have a neuroprotective in acute brain ischemia. The safety and efficacy of RIC combined with endovascular thrombectomy (SERIC-EVT) trial is investigating the safety and efficacy of RIC for patients with acute ischemic stroke (AIS) who underwent EVT due to large vessel occlusion of the anterior circulation.

Methods:

SERIC-EVT is a multicenter, randomized, parallel-controlled, and blinded endpoint clinical trial. Patients are recruited from 10 hospitals in Jilin Province, Northeast China. Patients with anterior circulation AIS undergoing EVT due to large vessel occlusion are randomized in a 1:1 ratio to RIC or sham-RIC. Participants will receive standard medical treatment and an inflation pressure of 200 mmHg (RIC group) or 60 mmHg (sham-RIC group) twice daily for seven consecutive days.

Study outcomes:

The primary outcome is the proportion of patients with modified Rankin Scale (mRS) score of 0–2 on day 90. Secondary outcome measures include the National Institute of Health Stroke Scale, Barthel Index, and mRS scores obtained at 24 h, 7 days, 30 ± 3 days, and 90 ± 3 days post-EVT, recanalization rate, expanded Thrombolysis in Cerebral Infarction score, and symptomatic intracranial hemorrhage post-EVT. Mortality and all adverse events, including skin changes and pain scores, within the first 90 days will be used as safety outcome measures.

Sample size estimates:

Based on previous studies, we estimate a 14% difference in functional independence (the mRS ⩽2) between RIC and sham-RIC groups. Considering a significance level of 5% and power of 80%, and one-fifth of patients lost to follow up, the planned sample size is 498 patients (249 per group).

Discussion:

RIC might be a strategy that improves 3-month clinical outcomes in AIS patients who have undergone EVT due to large vessel occlusion of anterior circulation. SERIC-EVT will determine whether this is the case.
Navigating the club-to-international transition process: An exploration of English Premier League youth footballers’ experiences
Authors: Edwards Dom , Brannagan Paul Michael
Published: August 2022

This study investigated the experiences of youth footballers as they made their transition from club football to the England youth international football teams. The club-to-international transition focuses on the movement of an individual from club sport to international representation, a within-career transition that comes with its own specific demands, characterised by the dual stakeholders of club and national governing body. The authors completed semi-structured interviews with 11 current youth footballers to better understand the type of coaching support they were provided by both club and national team coaches before, during and after international representation. Through thematic analysis, it was found that there was ambiguity as to the support offered to youth international footballers, with players explaining that feedback provided post-training camp did not support them in their development. Players also suggested the importance of sharing performance data between the domains (club and international) as good practice that helped them to have a more successful transition. These novel results suggest that the transition into youth international football should be seen as an important step in the development of the young footballer, however, clubs and national governing bodies need to work closer together to use this transition as a developmental opportunity. Several practical applications are discussed, including the importance of key stakeholders clearly outlining their responsibilities to the player during international representation.
Acute effects of ballistic and non-ballistic conditioning activities on the punching impact of amateur boxers
Authors: Yi Wenjuan , Wang Dexin , Chen Chao , Wu Rui
Published: August 2022

Objectives

This study investigated the postactivation performance enhancement (PAPE) effects of medicine ball throwing (MBT) and bench pressing (BP) on punching impact at different recovery times.

Methods

Fourteen amateur boxers performed three lead-hand (lead-hand) and rear-hand straight punches (rear-hand) at 3, 6, 9, 12, and 15 min after MBT or BP exercise. Peak force, time to the peak force, and rate of force development (RFD) of each punch was measured by a force plate.

Results

There was no significant condition × time interaction effect for any variables (lead-hand: F = 0.744–0.913, p = 0.448–0.542; rear-hand: F = 0.240–1.355, p = 0.245–0.944). No significant main effect for condition for any variables (lead-hand: F = 0.103–0.219, p = 0.644–0.751; rear-hand: F = 0.070–0.459, p = 0.504–0.793). The time effect was significant on peak force ( F = 4.411, p = 0.005) and RFD ( F = 5.002, p = 0.002) of lead-hand, time to the peak force ( F = 5.791, p = 0.001) and RFD ( F = 5.514, p = 0.001) of rear-hand. Peak force and RFD of the lead-hand, as well as time to the peak force and RFD of the rear-hand enhanced significantly at 6–15 min ( p = 0.001–0.042), compared to the baseline.

Conclusions

MBT and BP may equally enhance punching impact for amateur boxers; moreover, there was no difference in recovery time between conditioning activities.
Identification of individuals at risk for postoperative cognitive dysfunction (POCD)
Authors: Yang Xiao , Huang Xinwei , Li Min , Jiang Yuan , Zhang Hong
Published: August 2022

Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term cognitive decline, raising the need for a broad screening to identify individuals at risk for POCD during the perioperative period. In this narrative review, we summarize preoperative, intraoperative and postoperative risk factors for POCD reported in last 5 years and discuss neuropsychological tools and potential biomarkers and time points for assessment that might be suitable for clinical use. We aim to provide crucial information for developing a strategy of routine screening for POCD, which may assist with better identification of at-risk individuals for early interventions. Very importantly, the utilization of a standardized strategy may also allow higher consistency and comparability across different studies.
Chinese guideline on the application of anti-seizure medications in the perioperative period of supratentorial craniocerebral surgery
Authors: Liang Shuli , Fan Xing , Chen Feng , Liu Yonghong , Qiu Binghui , Zhang Kai , Qi Songtao , Zhang Guojun , Liu Jinfang , Zhang Jianguo , Wang Jun , Wang Xiu , Song Ziyang , Luan Guoming , Yang Xuejun , Jiang Rongcai , Zhang Hua , Wang Lei , You Yongping , Shu Kai , Lu Xiaojie , Gao Guoyi , Zhang Bo , Zhou Jian , Jin Hai , Han Kaiwei , Li Yiming , Wei Junji , Yang Kun , You Gan , Ji Hongming , Jiang Yuwu , Wang Yi , Lin Zhiguo , Li Yan , Liu Xuewu , Hu Jie , Zhu Junming , Li Wenling , Wang Yongxin , Kang Dezhi , Feng Hua , Liu Tinghong , Chen Xin , Pan Yawen , Liu Zhixiong , Li Gang , Li Yunqian , Ge Ming , Fu Xianming , Wang Yuping , Zhou Dong , Li Shichuo , Jiang Tao , Hou Lijun , Hong Zhen
Published: August 2022

Seizures are a common symptom of craniocerebral diseases, and epilepsy is one of the comorbidities of craniocerebral diseases. However, how to rationally use anti-seizure medications (ASMs) in the perioperative period of craniocerebral surgery to control or avoid seizures and reduce their associated harm is a problem. The China Association Against Epilepsy (CAAE) united with the Trauma Group of the Chinese Neurosurgery Society, Glioma Professional Committee of the Chinese Anti-Cancer Association, Neuro-Oncology Branch of the Chinese Neuroscience Society, and Neurotraumatic Group of Chinese Trauma Society, and selected experts for consultancy regarding outcomes from evidence-based medicine in domestic and foreign literature. These experts referred to the existing research evidence, drug characteristics, Chinese FDA-approved indications, and expert experience, and finished the current guideline on the application of ASMs during the perioperative period of craniocerebral surgery, aiming to guide relevant clinical practice. This guideline consists of six sections: application scope of guideline, concepts of craniocerebral surgery-related seizures and epilepsy, postoperative application of ASMs in patients without seizures before surgery, application of ASMs in patients with seizures associated with lesions before surgery, emergency treatment of postoperative seizures, and 16 recommendations.
Validation of the Simplified Disease Activity Index (SDAI) with a quick quantitative C-reactive protein assay (SDAI-Q) in patients with rheumatoid arthritis: a prospective multicenter cross-sectional study
Authors: Schally Julia , Brandt Henning Christian , Brandt-Jürgens Jan , Burmester Gerd R. , Haibel Hildrun , Käding Henriette , Karberg Kirsten , Lüders Susanne , Muche Burkhard , Protopopov Mikhail , Rios Rodriguez Valeria , Torgutalp Murat , Verba Maryna , Zinke Silke , Poddubnyy Denis , Proft Fabian
Published: August 2022

Objectives:

The Simplified Disease Activity Index (SDAI) is a recommended composite score for assessing the remission status in patients with rheumatoid arthritis (RA). However, determination of C-reactive protein (CRP) levels takes several hours and sometimes days and limits the use of the SDAI in the clinical setting. The aim of this study was to validate the SDAI using a quick quantitative C-reactive protein (qCRP) assay (as SDAI-Q) in RA patients.

Design:

This is a multicenter, prospective, cross-sectional pilot study in RA patients.

Methods:

Adult patients (⩾18 years) with a clinical diagnosis of RA were recruited between January 2020 and September 2020 from five rheumatologic centers located in Berlin, Germany. SDAI, SDAI-Q, Clinical Disease Activity Index (CDAI), and DAS28 scores comprising CRP, qCRP, or erythrocyte sedimentation rate (ESR) were calculated. The agreement of disease activity categories was analyzed using cross tabulations and weighted Cohen’s kappa. The agreement of numerical values was analyzed with Bland–Altman plots and intraclass correlation coefficients (ICCs).

Results:

Overall, 100 RA patients were included in the statistical analysis. The mean value of qCRP (7.89 ± 16.98 mg/l) was slightly higher than that of routine laboratory CRP (6.97 ± 15.02 mg/l). Comparing SDAI and SDAI-Q, all patients were assigned to identical disease activity categories. Agreement of disease activity categories by CDAI and SDAI/SDAI-Q was observed in 93% with a weighted Cohen’s kappa of 0.929 (95% confidence interval (CI) = 0.878; 0.981).

Conclusion:

The SDAI-Q showed an absolute agreement regarding the assignment of disease activity categories in comparison with the conventional SDAI. Therefore, the SDAI-Q may facilitate the application of a treat-to-target concept in clinical trials and clinical routine as a quickly available disease activity score incorporating CRP as an objective parameter.
Qualitative Evaluation of the Science Curriculum Applied in Science and Art Centers (SACs) for Gifted Students in Turkey Within the Framework of the CIPP Approach
Authors: Bodur Nurettin Can , Tuysuz Cengiz , Ugulu Ilker
Published: August 2022

This study was conducted using a qualitative approach as it aimed to evaluate the Science and Art Center Science Curriculum (SACSC), which was updated in 2020, within the framework of the context, input, process, and product (CIPP) approach by taking the opinions of science teachers working in Science and Art Centers (SACs) in Turkey. The data were collected according to the qualitative data collection method and a structured interview form was used as a data collection tool. The findings showed that science teachers working in SACs have generally negative views on SACSC based on the context dimension of the CIPP Model, while their views are generally positive based on input, process, and product dimensions. Based on the results of the research, it is recommended to conduct other comparative studies between the SACSC and similar curricula in other countries in order to reveal the relationship between the program components and the needs of children and society.
Evaluating the impact of coronavirus disease on burnout among healthcare workers using maslach burnout inventory tool: A systematic review
Authors: Tang Reanne , Feng Ouyuan , Chong Jin Jian , Wang Aiwen
Published: August 2022

Background

Burnout has been prevalent among healthcare workers (HCWs). However, the effect of the Coronavirus Disease (COVID-19) pandemic on this phenomenon in HCWs is unclear.

Objective

This systematic review aims to evaluate the impact of COVID-19 on burnout of HCWs using Maslach Burnout Inventory (MBI).

Methods

A systematic search was performed on PubMed database for articles published between 1 December 2019 and 30 June 2021. Search strategy combined terms for HCWs, COVID-19, burnout, and MBI. The main outcome of interest was burnout, including both mean prevalence and MBI scores for high emotional exhaustion (EE), high depersonalisation (DP) and low personal accomplishment (PA).

Results

Four cohort studies, 90 cross-sectional studies and one randomised-controlled trial were included for review. Only one cohort study compared burnout data among HCWs before and during COVID-19. It reported a statistically significant increase in mean EE and PA scores from 21.9 to 24.8 ( p = .001), and 42.7 to 48.7 ( p = .001), respectively. The remaining studies only evaluated burnout data during COVID-19 but were missing burnout data prior to the pandemic for comparison. Across these studies, the overall mean prevalence of burnout among HCWs was 39.95%, with mean MBI EE scores of 22.07, DP scores of 7.83, and PA scores of 32.53. Burnout outcomes were generally comparable across specific healthcare professions such as doctors and nurses.

Conclusion

Whilst quality research elucidating the effect of pandemic on burnout is lacking, current burnout prevalence among HCWs during COVID-19 is notable.
Long-term follow-up of patients treated with dupilumab for chronic spontaneous urticaria: A case report
Authors: Abadeh Armin , Lee Jason Kihyuk
Published: August 2022

Several therapeutic strategies have been established to achieve maximal remission and improve quality of life in patients with chronic spontaneous urticaria. We previously reported dupilumab as a novel therapy for antihistamine-refractory chronic spontaneous urticaria patients who failed to respond to administration of omalizumab at increased doses for longer durations. This is the first case series to report data on the long-term duration of chronic spontaneous urticaria remission after discontinuation of dupilumab in patients who were able to obtain controlled chronic spontaneous urticaria. Six patients diagnosed with chronic spontaneous urticaria, who failed to respond to antihistamines and prolonged therapy with omalizumab at increased doses, were followed in this study for up to 34 months following initiation of dupilumab therapy. By demonstrating the maintenance of chronic spontaneous urticaria remission with dupilumab following discontinuation of therapy, in 67% of the patients, over an observation period up to 22 months, this case series highlights dupilumab’s potential disease-modifying efficacy in patients affected by this disease.
Tele-yoga for the management of Parkinson disease: A safety and feasibility trial
Authors: James-Palmer Aurora M , Daneault Jean-Francois
Published: August 2022

Objectives

Despite current standard treatments, persons with Parkinson disease (PD) still experience motor and non-motor symptoms that impact daily function and quality of life, warranting the investigation of additional interventions. Holistic complementary interventions such as yoga have been shown to be beneficial for persons with PD. However, there are multiple barriers to in-person interventions such as transportation difficulties and disease-related mobility impairments which may be mitigated by digital health applications. Therefore, this study’s purpose was to assess the safety and feasibility of a synchronous tele-yoga intervention for persons with PD.

Methods

Sixteen participants were enrolled in a single group safety and feasibility trial. The entire study was conducted remotely and consisted of a baseline assessment followed by a six-week waiting period, then a second assessment, a six-week tele-yoga intervention period, a post-intervention assessment, a six-week follow-up period, and lastly a follow-up assessment. During the tele-yoga period, participants completed two one-on-one 30-minute tele-yoga sessions weekly for a total of 12 sessions. Primary outcomes included adverse events, adherence, technological challenges, and usability. Secondary outcomes included enjoyment and clinically relevant outcome measures assessing both motor and non-motor symptoms.

Results

No severe adverse events were attributed to the intervention. Retention was 87.5%, assessment session adherence was 100%, and intervention session adherence was 97%. Technological challenges did not impact feasibility. The intervention was usable and enjoyable. While this study was not powered or designed to assess the efficacy of the intervention, preliminary improvements were shown for some of the clinically relevant outcome measures.

Conclusions

Overall, this study showed that the implementation of a synchronous one-on-one tele-yoga intervention was safe, feasible, usable, and enjoyable for persons with PD. Randomized control trials investigating its efficacy should be initiated. The study was registered with ClinicalTrials.gov (NCT04240899, https://clinicaltrials.gov/ct2/show/NCT04240899).
The Lynching Era and Contemporary Lethal Police Shootings in the South
Authors: Lyons Christopher J. , Painter-Davis Noah , Medaris Drew C.
Published: August 2022

The rate of police-involved killings in the U.S. greatly exceeds that of other industrialized nations and is highly racially disproportionate. Yet, we know relatively little about the antecedents of police violence, and even less about what explains the distribution of police killings across space. We ask whether there is a connection between contemporary police killings in the U.S. and the country's unique history of racial subjugation and violence. We focus particularly on lynching era violence in the South between 1877 and 1950 during which vigilantes killed thousands of Blacks and hundreds of Whites. We propose three main pathways through which lynchings shape law enforcement practices today: legacies of racialized criminal threat, brutalization, and legal estrangement. Analyzing Mapping Police Violence data that provide a more complete picture of lethal police force than currently available government databases, we find that lynching, regardless of victim race, moderately associates with present-day lethal police shootings of Blacks. We find some evidence that lynching also associates with lethal shootings of Whites, although this finding depends of model specification. On balance, our results suggest that lynching's legacy for law enforcement may operate through enduring cultural supports for severe punishment.
Segmental Slope is a Predictor of Fusion Rate in Single Level Anterior Cervical Discectomy and Fusion
Authors: Sheng Xia-Qing , Ding Chen , Wang Bei-Yu , Meng Yang , Liu Hao
Published: August 2022

Study design

Retrospective study

Objectives

To explore preoperative segmental slope as a predictor of fusion rate after single-level anterior cervical discectomy and fusion (ACDF).

Methods

Data of consecutive patients with single-level cervical spondylosis who underwent ACDF between 2011 and January 2019 were retrospectively reviewed. Preoperative parameters including baseline characteristics, segment slope, T1 slope, range of motion, intervertebral disk height, and bone density were evaluated. Data were analyzed using Student’s t-test, Mann–Whitney U test, χ2 test, Fisher’s exact test, multivariate logistic regression analysis, and receiver operating characteristic curve.

Results

In total, 253 patients were selected. The mean follow-up was 32.1 months (range 24-99 months). Male sex, body mass index, preoperative segment slope, T1 slope, operative levels, and osteoporosis or osteopenia were associated with non-fusion at an early stage after surgery. However, no statistically significant difference was observed at the last follow-up. Multivariate logistic regression analysis revealed that the preoperative segment slope was an independent predictor for non-fusion at 3, 6, and 12 months postoperatively. Osteoporosis or osteopenia was an independent predictor of non-fusion at 6 and 12 months postoperatively. The area under the curve was .874 at 3 months ( P < .001, cutoff value 10.21°), .888 at 6 months ( P < .001, cutoff value 14.56°), and .825 at 12 months ( P < .001, cutoff value 21.08°).

Conclusion

Preoperative segment slope can be used as a predictor of early fusion rate after single-level ACDF. We determined detailed cutoff values. This study may help surgeons take measures to promote early fusion in advance.
Patients’ Experiences Using Closed Incision Negative Pressure Wound Therapy Dressing After Infra-Inguinal Vascular Surgery
Authors: Nyman Johan , Acosta Stefan , Monsen Christina , Hasselmann Julien , Rezk Francis , Andersson Ann-Christine
Published: August 2022

The PICO™ dressing utilizes incisional negative pressure wound therapy in reducing surgical site infection after vascular surgery; however, no patient-reported investigations are available. The objective was to explore patientś experiences wearing the PICO™ dressing for 7 days. Nine men and 6 women were interviewed, and analysis was conducted using qualitative content analysis. The PICO™ dressing system was well accepted by most patients. Most prominent problems were fear of dropping the pump to the floor, lack of information, and initial feelings of uncertainty. Four patients who had the PICO™ and standard dressing in opposite groins simultaneously, preferred the PICO™ dressing.
Quality of Life, Social, and Emotional Aspects of Being Diagnosed With Multiple Sclerosis: What's Grit got to do With it?
Authors: Klappa Susan G. , Block Kelli , Grant Taylor
Published: August 2022

The purpose of this study was to determine the extent to which grit influences the quality of life (QOL) in patients diagnosed with multiple sclerosis (MS). Mixed-methods included a survey (n  =  51) via Qualtrics utilizing the Grit Scale, Short Form-36 (SF-36), and general demographic questions and phenomenological interviews (n  =  14). Quantitative data were analyzed using the SPSS25. Qualitative data were analyzed using whole-parts-whole analysis. The average grit score for participants diagnosed with MS was 3.8  ±  0.5. Moderate correlations existed between grit scores and emotional role limitations (r  =  .542, P < .001), emotional well-being (r  =  .542, P < .001), and social functioning (r  =  .448, P < .001). Common themes that emerged from the phase II interviews included (a) an initial shock or relief factor, (b) an identity shift, and (c) advocacy and victories. Higher levels of grit correlate with a better QOL.
Twenty Years of Entrepreneurship and Innovation Research: A Bibliometric Analysis
Authors: Pathak Divya , Sharma Jai Prakash , Patnaik Susmita
Published: August 2022

The present study attempts to provide a bibliometric analysis of the research conducted on entrepreneurship and innovation. Utilising the Scopus database, a total of 1,103 papers, published from the year 1999 to 2018, have been analysed in this study. A classification of these papers is presented further on the basis of important journals, papers with maximum citations, year-wise publication trends, subject-wise distribution, most productive countries and institutions, and eminent authors. Further, the VOSviewer software is utilised for providing a co-authorship analysis, international collaboration patterns, keywords co-occurrences analysis, co-citation analysis and bibliographic coupling analysis. The results show that the research on this area has been rapidly growing; the maximum papers have been contributed by developed countries such as the USA, UK and China. Furthermore, the most cited paper is about entrepreneurship, innovation and economic growth, and the maximum research has been carried out in the subject areas of business, management and accounting.
Rotator Cuff Repair With a Bioinductive Patch
Authors: Forsythe Brian , Knapik Derrick M. , Patel Harsh H. , Berlinberg Elyse J. , Chahla Jorge , Freehill Michael T. , Riboh Jon
Published: August 2022

Background:

As a degenerative condition, symptomatic rotator cuff disease is frequently seen in the aging population, often requiring arthroscopic repair to eliminate pain and restore function. Repair integrity remains a concern in both short- and long-term postoperative periods due to high rates of primary repair failures, leading to increased interest in biologic patch augmentation to improve healing.

Indications:

Patch augmentation during rotator cuff repair is indicated in patients at high risk for repair failure or incomplete healing, including patients with poor quality, degenerative tendon tissue, those undergoing revision repair, and patients with large or massive rotator cuff tears.

Technique Description:

Standard arthroscopic portals are established and following diagnostic arthroscopy, the rotator cuff tear is identified, mobilized, and the humeral head gently debrided to a bleeding surface. Medial row suture anchors are placed, and following suture passage through the rotator cuff, the medial row sutures are tied. A bioinductive augmentation patch is introduced and provisionally secured medial to the enthesis utilizing spinal needles. Sutures are shuttled over the patch and incorporated into the lateral row repair utilizing 2 knotless suture anchors, effectively securing the patch over the bone-tendon interface.

Results:

Utilization of the described patch augmentation technique may improve repair healing by stimulating collagen formation and tissue vascularity, while providing structural support during the immediate postoperative period, effectively facilitating new tissue formation.

Discussion/Conclusion:

Incorporation of the bioinductive patch into the lateral row suture repair, directly over the tendon-bone interface, may assist in repair healing and decrease issues related to patch migration, while minimizing operative time and materials cost.
Transferability analysis of built environment variables for public transit ridership estimation in Wuhan, China
Authors: Fang Zhixiang , Zhang Lupan , Zheng Meng
Published: August 2022

New stations (such as metro stations) will bring remarkable changes to the local transportation and economic development. Understanding patterns of factors which importantly impact on public transit ridership in the surrounding areas of new stations is essential to their construction planning, like estimating the possible ridership. Built environment variables with high importance magnitude, which were thought applicable to estimate public transit ridership in other areas of the same category, were described as transferable variables (TVs) in this study. A transferability analysis method of the built environment for the ridership estimation was constructed by adopting partial least square regression (PLSR) based on available data. Taking Wuhan, China as an example, this study analyzed the changes and differences of the built environment variables in different categories of pedestrian catchment areas (PCAs) of metro stations on the importance and transferability magnitude for the metro and taxi ridership, based on the metro and taxi data of one week in January, April, and June. Performances of the ridership estimation based on TVs and all the built environment variables were compared. This study inferred that (1) most of the land use variables (about 85%) showed important influence on the metro and taxi ridership, while only about 18% of the other variables showed key impact. The importance magnitude of the built environment variables was mainly related to PCA categories and public transportation modes, but less related to time. (2) Highly important built environment variables also tended to be highly transferable. Transferability magnitude of the built environment variables for the ridership was related to PCA categories and types of public transport. (3) Compared to all the built environment variables, using TVs, the relative accuracy of the metro and taxi ridership estimation was around 20% and 18% higher respectively.
Mutations of TFPI-binding exosites on factor VII cause bleeding phenotypes in factor VII deficiency
Authors: Seanoon Karnsasin , Payongsri Panwajee , Vivithanaporn Pornpun , Sirachainan Nongnuch , Chuansumrit Ampaiwan , Hongeng Suradej , Tanratana Pansakorn
Published: August 2022

Tissue factor (TF) pathway inhibitor (TFPI) is a Kunitz-type anticoagulation protein that inhibits activated factor VII (FVIIa)/TF complex. Incidentally, many different F7 gene variants, including TFPI-binding exosite mutations, have been reported in patients with congenital FVII deficiency and clinical bleeding variabilities. Here, TFPI-binding exosites (R147 and K192) on FVII zymogen were selectively disrupted to understand their roles in the pathogenesis of bleeding phenotypes. Expression of recombinant FVII variants (R147A, K192A, and R147A/K192A) demonstrated markedly reduced secretion of FVII owing to intracellular retention in the endoplasmic reticulum, as demonstrated by upregulation of the unfolded protein response genes in all FVII variants. FVII variants showed a similar FVII activation pattern and FVIIa amidolytic activity than FVII wild-type (WT). In contrast to FVII activation, R147A and K192A showed a 90% reduction in FX activation relative to WT, whereas the R147A/K192A variant demonstrated a 99% decrease in FX activation. The clotting time was markedly prolonged with R147A and K192A than WT, and no FVII coagulant activity was detected in R147A/K192A. In addition, the thrombin generation assay revealed a significant prolongation of lag time in all FVII variants. Our study explains how mutations of TFPI-binding exosites of FVII can lead to bleeding phenotypes in individuals carrying these aberrancies.