bluuebunny/crossref_metadata_2025 huggingface dataset:
OBD Communications Compliance Test Cases for Heavy-Duty Components and Vehicles
Authors:   Truck Bus Control and Communications Network Committee
Published: June 2023

The purpose of this SAE Recommended Practice is to verify that vehicles and/or components are capable of communicating a required set of information, which is described by the diagnostic messages specified in SAE J1939-73, that is in accordance with off-board diagnostic tool interface requirements contained in the government regulations cited below.

This document describes the tests, methods, and results for verifying diagnostic communications from an off-board diagnostic tool (i.e., scan tool) to a vehicle and/or component. SAE members have generated this document to serve as a guide for testing vehicles for compliance with ARB and other requirements for emissions-related on-board diagnostic (OBD) functions for heavy-duty engines used in medium- and heavy-duty vehicles.

The development of HD OBD regulations by U.S. EPA and California’s Air Resources Board (ARB) require that diagnostic message services are exercised to evaluate diagnostic communication standardization requirements on production vehicles. The user should reference the summary provided by SAE J1939-73 Tables 1 and 2 for OBD compliance support, and the discussion in SAE J1939-73 Appendix H for additional implementation concepts.
The Effect of Online Communication and Use of Information Systems on Audit Quality
Authors: Natita Rendi Kusuma , Maryani Neni
Published: June 2023

During the Covid-19 pandemic it became a challenge for the Public Accounting Firm to carry out audit procedures. During the Covid-19 pandemic, physical meetings or communication between auditors or public accountants and a company's clients were limited, so these meetings, which were generally held face-to-face, became online meetings. The main obstacle for auditors or public accountants during the Covid-19 pandemic is that the audit procedures that must be carried out for the 2020 financial statements will be different from the previous year. In general, audit engagements or communication with clients to obtain audit evidence is carried out face-to-face, but to reduce the spread of the Covid-19 virus, such communication is carried out online. Of course, these communication issues must still be guided by Auditing Standard 260 regarding communication with those charged with governance. This study aims to determine the effect of online audit communication and the use of information systems on audit quality. This research is research with the aim of testing the hypothesis. Studies that engage in hypothesis testing usually explain the nature of a particular relationship or determine the independence of two or more factors in a situation. This study uses an explanatory method where the researcher wants to find the cause of one or more problems. This study aims to determine the effect of online audit communication and the use of information systems on audit quality. This research is research with the aim of testing the hypothesis. Studies that engage in hypothesis testing usually explain the nature of a particular relationship or determine the independence of two or more factors in a situation. This study uses an explanatory method where the researcher wants to find the cause of one or more problems. This study aims to determine the effect of online audit communication and the use of information systems on audit quality. This research is research with the aim of testing the hypothesis. Studies that engage in hypothesis testing usually explain the nature of a particular relationship or determine the independence of two or more factors in a situation. This study uses an explanatory method where the researcher wants to find the cause of one or more problems.
The Effect of Sugar Solution Concentration on Characteristics of Candied Dried Tomatoes (Solanum lycopersicum L.)
Authors: Ningrumsari Ida , R Moch Alhikam Afrijal , Nurulhusna Rimba Tsania
Published: June 2023

Tomatoes are a type of food that has high production and is a perishable food. In addition, the utilization of processed tomatoes as a food source is still not optimal. So, it is necessary to do the right food processing on tomatoes, one of which is processed into dried candied. The purpose of this study was to determine the concentration of sugar solution, so as to produce dried candied with good characteristics. The research was conducted at the Chemistry Laboratory and Food Processing Laboratory, Faculty of Agriculture, Ma'soem University from May to July 2022. The method used is the old experimental method, namely the Randomized Block Design (RBD) consisting of 6 (six) treatments and each repeated 4 (four) times. The treatments given were concentration A (40%), B (45%), C (50%), D (55%), E (60%), F (65%). The analysis in this study included water content, total dissolved solids. Meanwhile, organoleptic testing was carried out on the color, aroma, taste, and hardness of the dried candied produced. The results showed that the concentration of sugar solution had a significant effect on water content, total dissolved solids, and organoleptic properties. Only partially significant influenced the organoleptic properties of the dried candied produced. The results of the study can be concluded that the concentration of 55% sugar solution produces good characteristics of candied dried tomatoes, this determination is based on the level of color preference of 3.97, aroma of 4.38 and taste of 4.48 from a maximum value of 5.00, moisture content of 9.04% and total dissolved solids content of 62.80%.
Analysis of the Marketing Channel of Palasari Arabica Coffee Beans
Authors: Pardani Cecep , Mulyatillah Waliah , Fadhillah Luthfia Nur
Published: June 2023

The coffee agro-industry has enough opportunities significant for conducted development where Thing could see from amount starting request increase. Ground coffee is one of the results of processing from coffee beans that have prospects as well as good market opportunities. This study aims to determine: Arabica coffee bean marketing channels in Giri Mekar Village, Cilengkrang District, Bandung Regency; The amount of Arabica coffee bean marketing margin at the level of Arabica coffee marketing agency in Giri Mekar Village, Cilengkrang District, Bandung Regency; The costs and benefits of Arabica coffee marketing in Giri Mekar Village, Cilengkrang District, Bandung Regency; Farmer's Share Arabica coffee in Giri Mekar Village, Cilengkrang District, Bandung Regency. The type of research used is a survey. Respondents in this study were 10% of Arabica coffee farmers in Giri Mekar Village as many as 30 people, 1 person collecting traders, and 5 industrial consumers. The results of this study indicate that there is one marketing channel for robusta coffee beans in Giri Mekar Village, Cilengkrang District, Bandung Regency, namely farmers, collector traders, and industrial Consumers. The amount of marketing margin on the marketing channel is IDR 75,000 per kilogram. The amount of marketing costs in the marketing channel is IDR 46,500 per kilogram. The marketing profit on the marketing channel is IDR 29,500 per kilogram. Farmer's Share on the marketing channel is 16.67%
Göçmen sineması ve varoluşçuluk: Üç film üzerinden varoluşsal bir değerlendirme
Authors: Uyanık Necip
Published: June 2023

Bu çalışmada farklı coğrafyalardan Avrupa’ya geçmeye çalışan bireylerin Avrupalı bireylerle birlikte yaşadığı varoluşsal sorunlar konu edilmiştir. Bu nedenle çalışma sadece göç sorununu ele alan bir amaca sahip değildir. Bu amaç doğrultusunda sinemanın gücünü ve büyüleyici dünyasını referans alınarak göç konusu varoluşçu felsefe bağlamında incelenmeye çaba gösterildi. Bunu gerçekleştirmek için göçmen sinemasının üç filmi örneklem olarak seçildi. Bu çerçevede Reise der Hoffnung (Umuda Yolculuk, Xavier Koller, 1990), Welcome (Hoşgeldiniz, Philippe Lioret, 2009), Terraferma (Memleket, Emanuele Crialese, 2011) filmlerindeki umut/umutsuzluk, yalnızlık, dışlanmışlık, uzaklaşma, yabancılaşma gibi varoluşsal sorunlar analiz edildi. Buna göre söz konusu filmlerdeki varoluşsal diyaloglar tespit edilmeye çalışılmış ve seçilen filmler merkeze alınarak göç süresince yaşanılan somut gerçeklikler varoluşsal bir bakış açısıyla tartışılmıştır.
Farklı Bitki Ekstrakt ve Esansiyel Yağların Lakerda Örneklerinden İzole Edilen Bakteriler Üzerine Antibakteriyel Etkilerinin Araştırılması
Authors: KAHRAMAN YILMAZ Dilek , BERİK Nermin
Published: June 2023

Bu çalışmada turunç çiçeği, karanfil tanesi ve portakal kabuğu yağları ve etanolik ekstraktlarının; lakerda örneklerinden izole edilen bakteriler üzerinde in vitro koşullarda antibakteriyel etkileri araştırılmıştır. Sonuçlara göre; esansiyel yağların etanolik ekstraktlara göre daha etkili olduğu belirlenmiştir. Turunç çiçeği ve karanfil tanesi esansiyel yağları; Pseudomonas fluorescens, Staphylococcus pasteuri, Staphylococcus equorum, Carnobacterium mobile, Carnobacterium maltaromaticum, Vibrio hibernica ve Vibrio rumoiensis bakterileri üzerinde güçlü etki göstermiştir. Esansiyel yağlar en yüksek inhibisyon etkisini, C. mobile üzerinde göstermiştir. Bu tür üzerinde turunç çiçeği %0,00977 ve karanfil tanesi %0,00488 konsantrasyon ile esansiyel yağlarının etkili olduğu bulunmuştur. Turunç çiçeği esansiyel yağının Staphylococcus pasteuri üzerinde %0,3125 konsantrasyon ile daha güçlü bir inhibisyon sağlanmıştır. En az etki %1,25 konsantrasyon ile karanfil esans yağında S. pasteuri bakterisine karşı tespit edilmiştir. Bu çalışmada turunç çiçeği ve karanfil tanesi esansiyel yağlarının, test edilen bakteriler üzerinde güçlü inhibisyon etkisi olduğu belirlenmiştir. Sonuç olarak, bulgular gıda güvenliğini sağlamak için lakerdalarda; turunç çiçeği ve karanfil tanesi esansiyel yağlarının kullanılabilirliğini desteklemektedir.
Crime prevention in special (free) economic zones
Authors: Veselovska Nataliia , Sieriebriak Stanislav , Petkov Valerii , Dovban Igor , Udod Andrii
Published: June 2023

The objective of the study was to determine the specific aspects and prospects of crime prevention in special economic zones as special economic and geographical entities. In the course of the research a set of practical methods was applied: doctrinal, comparative and prognostic approach. The risk of crime in the zones depends on the particular economic activity and the actors involved. The current criminal structure in free trade zones is dominated by illegal trade and infringement of intellectual property rights. However, the structuring of crime commonly depends on two factors: a) the division of zones into external/internal; and b) characteristics of the economic system of the country where the zone is located. The entities dedicated to crime prevention are classified as special and non-special, with international entities and representatives of the private sector standing out. It is concluded that the prospects for crime prevention in this area are related to the involvement of the capacities of international actors and the action of representatives of the private sector, taking into account the particular characteristics and conditions of countries with a transitive economy and a particular legal system.
Peculiarities of representative authorities functioning in ukraine under conditions of war
Authors: Goshovska Valentyna , Pukhkal Oleksandr , Reiterovych Ihor , Mysyshyn Oleksandr , Serhov Sergii
Published: June 2023

The large-scale invasion of the Russian Federation into the territory of Ukraine has significantly destabilized the processes of functioning of representative authorities in Ukraine and, moreover, has led to destructive changes due to the annexation of the country's territories. The article aims to study the theoretical and applied foundations of peculiarities of functioning of representative institutions in Ukraine, during the war. The methodological basis of the study consists of general and special scientific methods of cognition and economic and legal analysis, in particular: systems analysis, synthesis, abstraction, comparison, analogy, statistical analysis, functional analysis, clustering, cluster analysis (based on the k-means method), correlation and regression analysis, graphical, tabular, generalization and systematization. The results of the theoretical studies carried out allow us to establish a significant impact on the destabilizing factors of the external and internal environment, the most important of which are the military factors. In conclusion, significant imbalances have been revealed in the process of ensuring the implementation of the principles of democracy in the activities of representative institutions.
Presentation of legal norms of the anti-corruption policy in order to form the professional competence of higher education students
Authors: Shchekhovska Larysa , Gavrylechko Yuriy , Vakuliuk Vasyl , Bardachov Viktor , Husarina Nataliia
Published: June 2023

Using the scientific method, the main objective of the study was to identify key legal norms and aspects of anti-corruption policy in order to form the legal and professional competence of students of higher education institutions. One of the most pressing issues is corruption in public authorities and administration, which to a greater or lesser extent affects almost the entire system of public administration. A small number of criminal cases of bribery indicates a high level of latency of these crimes. The spread of this negative phenomenon is facilitated by the imperfection of legislation, in particular, economic legislation. A large number of laws, departmental instructions, orders, etc., which often contradict each other and thus create significant difficulties for the officials themselves and deprive them of any opportunity to understand the legislation regulating the matter. It is concluded that, many laws contain ambiguous language in the text, which allows officials to interpret their content in their favor.
The Efficiency of the K-L Estimator for the Seemingly Unrelated Regression Model: Simulation and Application
Authors: Alaba Oluwayemisi Oyeronke , Kibria B. M. Golam
Published: June 2023

This paper considers the Ridge Feasible Generalized Least Squares Estimator (RFGLSE), Ridge Seemingly Unrelated Regression RSUR and proposes the Kibria-Lukman KLSUR estimator for the parameters of the Seemingly Unrelated Regression (SUR) model when the regressors of the models are collinear. A simulation study was conducted to compare the performance of the three different types of estimators for the SUR model. Different correlation levels (0.0, 0.1, 0.2, ..., 0.9) among the independent variables, sample sizes replicated 10000 times and contemporaneous error correlation (0.0, 0.1, 0.2, ..., 0.9) among the equations were assumed for the simulation study. The efficiency of the three (RFGLSE, RSUR, and KLSUR estimators for SUR, when the predictors are correlated, was investigated using the Trace Mean Square Error (TMSE). The results showed that the KLSUR estimator outperformed the other estimators except for a few cases when the sample size is small.
Making a Life on Mean Welfare
Authors: Mitchell Emma
Published: June 2023

Based on ethnographic fieldwork and the author's own experience, this book explores how diverse welfare users navigate the personal and practical hurdles of Australia's social security system.
Researching with Care
Authors: Brannelly Tula , Barnes Marian
Published: June 2023

This book demonstrates how an ethics of care can help researchers work through challenges and solve complex issues. Keeping social justice at the heart of research, the book shows how an ethics of care can provide a systematic approach supporting good judgements about research practices from inception to impact.
Kết quả tầm soát ung thư cổ tử cung các trường hợp ASCUS hoặc LSIL có nhiễm HPV tại Bệnh viện Từ Dũ
Authors: Phạm Hồ Thuý Ái , Trịnh Ngọc Hà Thư , Bùi Chí Thương , Vũ Thế Bình , Hà Hiếu Thảo
Published: June 2023

Mục tiêu: Xác định tỷ lệ CIN 2+ ở các trường hợp ASCUS hoặc LSIL có nhiễm HPV nguy cơ cao và một số yếu tố liên quan đến tình trạng CIN 2+.

Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả loạt ca hồi cứu trên đối tượng phụ nữ từ 30 tuổi trở lên có tế bào học ASCUS hoặc LSIL có nhiễm HPV nguy cơ cao tại Đơn vị kỹ thuật chẩn đoán - Khoa Khám phụ khoa Bệnh viện Từ Dũ từ tháng 12/2020 đến tháng 04/2021.

Kết quả: Trong 184 trường hợp nghiên cứu, tỷ lệ CIN 2+ là 21,2%, trong đó tỷ lệ CIN 2 là 6,0%, tỷ lệ CIN 3 là 13,6%, tỷ lệ ung thư là 1,6%. Tỷ lệ CIN 2+ có liên quan đến số bạn tình (PR = 3,39; KTC 95%: 1,56 - 7,36; p = 0,002), vệ sinh âm hộ sau quan hệ (PR = 2,94; KTC 95%: 1,41 - 6,13; p = 0,004), tiếp xúc khói thuốc lá (PR = 2,75; KTC 95%: 1,21 - 6,25; p = 0,016), nhiễm HPV 16 (PR = 3,80; KTC 95%: 1,37 - 10,53; p = 0,01).

Kết luận: Các trường hợp ASCUS hoặc LSIL nhiễm HPV nhóm nguy cơ cao có tỷ lệ CIN 2+ còn khá cao, cần theo dõi sát các trường hợp này trước khi trở về theo dõi thường quy.
Kích thích DouStim: cập nhật bằng chứng mới từ ESHRE
Authors: Đặng Tuấn Anh , Lê Hoàng
Published: June 2023

Kích thích buồng trứng kép (DuoStim), ban đầu chỉ được đề xuất để bảo tồn khả năng sinh sản khẩn cấp ở bệnh nhân ung thư, nhưng hiện nay ngày càng được sử dụng nhiều trong thụ tinh trong ống nghiệm (IVF) trên lâm sàng, đặc biệt ở nhóm bệnh nhân có đáp ứng kém (POR), tuổi cao dự trữ buồng trứng giảm hay có chỉ định làm xét nghiệm di truyền tiền cấy ghép mà tạo được ít phôi. Nhờ vào lý thuyết mới về sóng tuyển dụng nang noãn, các nang noãn được chiêu mộ liên tục bởi các làn sóng tuyển mộ khác nhau, trong cùng một chu kỳ có hai đến ba làn sóng chiêu mộ, cho phép có thể thu được nhiều tế bào noãn hơn trong một chu kỳ IVF. Việc áp dụng thành công giao thức kích thích buồng trứng ở giai đoạn hoàng thể đã thúc đẩy nghiên cứu về DuoStim (kích thích cả giai đoạn nang trứng - FPS và hoàng thể - LPS) trong một chu kỳ kinh nguyệt để tối đa hóa số lượng tế bào noãn và phôi trong thời gian ngắn nhất có thể. Các nghiên cứu gần đây đã chứng minh khả năng tạo phôi nang nguyên bội thu được ở pha FPS và LPS là tương tự nhau khi được trigger bằng hCG. Hơn nữa, DouStim có thể giảm bớt căng thẳng về tinh thần và cảm xúc cho những phụ nữ có tiên lượng xấu không lấy được trứng trong FPS. Do đó, DouStim được coi là một phác đồ đầy hứa hẹn cho những người đáp ứng buồng trứng kém hay tạo được ít phôi mà có chỉ định sàng lọc phôi tiền làm tổ sẽ có nhiều cơ hội hơn để thu được thêm  các tế bào noãn và phôi nang trong một chu kỳ kinh nguyệt. Bằng chứng mới từ ESHRE về phác đồ DuoStim cho thấy tổng số tế bào noãn MII và số phôi chất lượng tốt ở bệnh nhân POR không có sự khác biệt so với hai chu kỳ IVF liên tiếp. Nhưng kích thích buồng trứng trong pha hoàng thể hiệu quả hơn kích thích pha nang noãn khi dùng Progestin để ức chế đỉnh LH trên bệnh nhân POR. Người bệnh có chỉ định làm xét nghiệm di truyền tiền cấy ghép cho các bệnh đơn bội và xét nghiệm thể dị bội (PGT-M/A) mà trước đó chỉ thu được ≤5 phôi nang, phác đồ Doustim có thể sẽ mang lại nhiều lợi ích hơn.
Gluteal Tendon Tear Healing on Ultrasound 10 Weeks Following a Single Platelet-Rich Plasma Injection: A Case Report
Authors: Mubark Hassan
Published: June 2023

Tendinosis with or without tendon tear is a common form of tendon pathology and should be managed differently from inflammatory tendinitis although both are termed tendinopathy.

The current tendinopathy management involves rest, icing, a brace, oral anti-inflammatory medicine, and physiotherapy. Should that fail a trial of Corticosteroid (CS) injection allow surgery as a last resort.

This article presents a middle-aged male, a human resources manager who suffered two occasions of tendinopathy with the first one being a gradual development of symptomatic right common flexor origin calcific tendinosis (golfer’s elbow) on ultrasound (USS) secondary to competitive squash that failed conservative management and USS-guided CS injection. He had a long-term symptomatic recovery after six weeks following a single autologous platelet-rich plasma (PRP) therapy. Three years later he injured his right hip following a twisting injury to the right hip/gluteal area resulted in debilitating symptoms, USS scan revealed gluteus minimus/ medius calcific tendinosis, a partial split tear of the gluteus minimus, and trochanteric bursitis. He failed physiotherapy and anti-inflammatory medicine. He elected PRP therapy over CS injection, he became symptoms free six weeks after the injection. Teen weeks post-injection USS revealed a complete resolution of gluteus minimus tendon tear and no trochanteric bursitis, no clear tendinosis features but calcifications present.

This case demonstrates the use of relatively safe affordable clinic-based PRP therapy for long-term symptomatic control of tendinopathy with/without a tear. This is superior to oral anti-inflammatory and CS injections. Additionally, the healing of the tendon tear could save people from avoiding invasive surgery with its complications and long recovery time.

Thanks to the regenerative healing power of the growth factors and signaling proteins in platelets that stimulate the internal mesenchymal stem cells. We recommend a large-scale randomized control trial to confirm those findings and standardization of the PRP technique, hoping regenerative medicine to become the mainstream therapy in several musculoskeletal pathologies, particularly in resistant injuries.
La mediación en situaciones de conflicto en la práctica docente multigrado de estudiantes normalistas
Authors: García Carlos Alfredo Damián
Published: June 2023

El objetivo de la investigación fue identificar situaciones de conflicto y estrategias de mediación implementadas por estudiantes normalistas en su práctica docente multigrado. Es un estudio cuantitativo descriptivo, que conforme a Andréu (2011) se utilizó la técnica de análisis de contenido temático, que considera la presencia de términos o conceptos, con independencia de las relaciones surgidas entre ellos. Se utilizó las listas de frecuencias, la identificación y clasificación temática y la búsqueda de palabras en contexto. De acuerdo con Perrenoud (2007) se analizaron 46 indicadores de reflexión presentes en los informes de la práctica docente multigrado, correspondientes a 26 estudiantes del 6° semestre de la Licenciatura en Educación Primaria de la Escuela Normal de Juchipila, Zacatecas. Se encontró que la mayoría de los estudiantes normalistas tienen situaciones de conflicto en: la comunicación, en el conocimiento y dominio de contenidos multigrado, en la atención, en las interacciones y en las explicaciones. Así mismo, se identificó las estrategias de mediación que más se implementaron, siendo: el diálogo reflexivo, garantizar el respeto, aplicación de acuerdos del grupo, la gamificación y actividades significativas a través de retos.
On Lightlike Submanifolds of Poly-Norden Semi-Riemannian Manifolds
Authors: KILIÇ Erol , ACET Tuba , YÜKSEL PERKTAŞ Selcen
Published: June 2023

In this paper, we introduce and examine invariant and semi-invariant lightlike submanifolds of a poly-Norden semi-Riemannian manifold. Also, we obtain some examples of such types submanifolds and study the conditions for both integrability and totally geodesic foliation description of distributions.
Hyper-Fibonacci and Hyper-Lucas Polynomials
Authors: MERSİN Efruz Özlem
Published: June 2023

In this paper, hyper-Fibonacci and hyper-Lucas polynomials are defined and some of their algebraic and combinatorial properties such as the recurrence relations, summation formulas, and generating functions are presented. In addition, some relationships between the hyper-Fibonacci and hyper-Lucas polynomials are given.
A New Approach on Some Special Curves
Authors: AĞIRMAN AYDIN Tuba , KOCAYİĞİT Hüseyin
Published: June 2023

In this paper, we obtain some characterizations for a Frenet curve with the help of an alternative frame different from Frenet frame. Also, in the present study we consider weak biharmonic and harmonic 1-type curves by using the mean curvature vector field of the curve. We also study 1-type and biharmonic curves whose mean curvature vector field is in the kernel of Laplacian. We give some theorems for them in the Euclidean 3-space. Moreover, we give the classifications of these type curves.
The Minus Partial Order On Endomorphism Rings
Authors: ÖZDİN Tufan
Published: June 2023

Let $S=End(M)$ be the ring of endomorphisms of a right $R$-module M. In this paper we define the minus parital order for the endomorphism ring of modules. Also, we extend study of minus partial order to the endomorphism ring of a (Rickart) module. Thus several well-known results concerning minus partial order are generalized.
Fibonacci collocation method for solving a class of nonlinear differential equations
Authors: ÇAKMAK Musa , ALKAN Sertan
Published: June 2023

In this study, a collocation method based on Fibonacci polynomials is used for approximately solving a class of nonlinear differential equations with initial conditions. The problem is firstly reduced into a nonlinear algebraic system via collocation points, later the unknown coefficients of the approximate solution function are calculated. Also, some problems are presented to test the performance of the proposed method by using error functions. Additionally, the obtained numerical results are compared with exact solutions of the test problems and approximate ones obtained with other methods in literature.
Aspectos determinantes para adoção de sistemas agroflorestais no brasil: revisão sistemática e metanálise
Authors:   , Ribeiro Julio Cesar Pereira
Published: June 2023

Os sistemas agroflorestais (SAFs) representam atividades agrícolas que otimizam o uso e cobertura da terra e possuem potencialidades ecológicas e econômicas. Apesar dos estudos sobre SAFs mostrarem resultados promissores, muitos agricultores ainda não adotam esse modelo de agricultura. Esta revisão sistemática e metanálise identificou quais desafios e barreiras interferem na tomada de decisão dos agricultores para adotar sistemas agroflorestais no Brasil. Dos 957 artigos identificados, 60 artigos foram incluídos na análise final após uma rigorosa revisão de triagem duplo-cega. Dos 60 artigos, 35 foram selecionados para extração de dados e utilizados para revisão sistemática, enquanto apenas 10 foram utilizados para metanálise. A revisão e metanálise mostraram que, embora os SAFs apresentem vantagens para aumento de renda e recuperação ambiental, a falta de informação torna-se uma das principais barreiras para a adoção do SAF. Agricultores com acesso à informação têm 2,21 vezes mais chances de adotar um SAF em comparação com agricultores sem acesso à informação. Além disso, existem vários desafios para adoção e aceitação do SAF no Brasil, incluindo políticas públicas, assistência técnica qualificada, acesso à terra, participação em cooperativas e associações, uso do SAF para recuperação de áreas degradadas, educação, comercialização do produto SAF, aplicação de metodologias participativas, acesso a crédito e subsídios. Esta revisão e metanálise destacou as lacunas existentes para a adoção do SAF e a ausência de estudos que apontassem os principais avanços com os SAFs. Pesquisas futuras sobre variáveis associadas à adoção do SAF devem, em primeiro lugar, criar um método de coleta de dados, um protocolo de pesquisa para orientar a condução da pesquisa do SAF. Isso permitirá a criação de um banco de dados para compor informações referenciais para acompanhar a evolução dos SAFs no Brasil e estabelecer políticas que estimulem sua expansão Palavras-chave: Agrofloresta. Acesso à Informação. Adoção de SAF. Agricultura Familiar. Agroecologia.
Proposição de uma nova rota simpliﬁcada para a síntese de pontos quânticos coloidais de CdTe: caracterização e estudo da cinética de crescimento
Authors:   , Maronesi Ray Nascimento
Published: June 2023

O desenvolvimento de nanoestruturas é de grande importância para aplicações tecnoló- gicas bem como para uma maior compreensão de fenômenos quânticos. Nesta escala, destacam-se os pontos quânticos, que são nanoestruturas cuja luminescência é tamanho- dependente. Estas estruturas podem ser sintetizadas tanto em abordagens bottom-up quanto em top-down. Em particular, a síntese de pontos quânticos coloidais usando rotas químicas é uma das mais empregadas, devido a variedade de aplicações possíveis para as nanoestruturas luminescentes produzidas desta maneira. Neste trabalho, apresentamos os resultados de uma nova rota de síntese para pontos quânticos coloidais de CdTe em meio aquoso. A grande vantagem sobre sínteses já bem conhecidas encontra-se na sua facilidade de reprodução bem como a simpliőcação de etapas experimentais complexas relatadas em trabalhos anteriores. A particularidade experimental encontra-se no método de obtenção do precursor calcogeneto à base de telúrio. Por meio de análises ópticas de fotolumi- nescência e absorbância aliadas ao modelo teórico DFL, o qual determina a distribuição de tamanhos das nanopartículas luminescentes, extraímos os parâmetros necessários para uma análise cinética da reação do crescimento dos pontos quânticos de CdTe. Os raios das nanopartículas obtidos analiticamente foram veriőcados experimentalmente através da técnica de microscopia de força atômica. Foi então realizada uma investigação dos modos de crescimento via análise cronomal de Nielsen, a qual permitiu deőnir os modos de crescimento predominantes. Palavras-chave: Pontos Quânticos CdTe. Modelo DLF. Cinética Crescimento Pontos Quânticos.
Coletivo de mulheres campesinas, produção de extratos vegetais e potencial de uso no milho agroecológico
Authors:   , Rodrigues Josiéle Botelho
Published: June 2023

Óleos essenciais (OEs) e hidrolatos (Hs) de plantas possuem potencial de uso no manejo de insetos-pragas e patógenos em sistema agroecológico. Objetivo desse estudo foi reportar a tra- jetória do grupo Anacauíta na extração de OEs e Hs de plantas nativas dos domínios Pampa e Mata Atlântica. As espécies utilizadas foram Baccharis dracunculifolia e Schinus molle para determinação da composição química dos OEs e a ação de seus OEs e Hs no controle dos inse- tos pragas da cultura do milho Spodoptera frugiperda e Sitophilus zeamais. A caracterização do grupo Anacuíta deu-se pela realização de entrevistas com perguntas abertas com cinco integran- tes. Utilizou-se a cromatografia gasosa acoplada à espectrometria de massas para a obtenção da composição química. Para a avaliação dos OEs e Hs no manejo dos insetos pragas foram testadas seis concentrações de OEs (1%, 0,5%, 0,25%, 0,125%, 0,0625% e 0,0312%) e cinco Hs (1:0, 1:1, 1:2, 1:4, 1:8) e mais três tratamentos controle: bifentrina (+), somente água e água + emulsificante (-). A avaliação dos efeitos letais da S.frugiperda foi realizada às 48h, e os efei- tos subletais seguiram após com a quantificação do número de indivíduos sobreviventes. Para o S.zeamais, foi realizada a contagem dos insetos e averiguado o peso final da massa dos grãos após 80 dias de armazenamento. No bioensaio de repelência, realizou-se o teste de arena livre, sendo testado 10 e 100% do H e 0,0312% e 1% do OE. Dos resultados obtidos, os produtos do grupo Anacauita apresenta aplicabilidades variadas, desde o uso humano até o uso agrícola e os componentes majoritários corroboram com as potencialidades. Os tratamentos testado não reproduziram efeito letal na S.frugiperda. No S.zeamais, os tratamentos não reduziram o cres- cimento populacional, por outro lado, o OE de B.dracunculifolia foi o que apresentou menor infestação e perda de peso dos grãos. Na repelência, ambos extratos das duas espécies demons- traram potencial. Os estudos devem ser continuados referentes ao potencial dos OEs e Hs na agricultura, pois estes se mostraram eficientes para o S.zeamais. Entretanto, resta avaliar testes de repelência das mariposas e lagartas. Palavras-Chave: Insetos-praga. Grupo Anacauita. Aroeira-salsa. Alecrim do campo.
Caracterização clínica e laboratorial de bovinos adultos desidratados experimentalmente
Authors:   , Santos Mayara Oliveira dos
Published: June 2023

A desidratação é o sinal clínico que expressa o déficit hídrico do organismo e, usualmente, está associada a desequilíbrios eletrolíticos e ácido base, que são frequentes na espécie bovina e são consequência de diferentes doenças. Muitos autores têm estudado os efeitos das desidratações e dos consequentes desequilíbrios hidroeletrolíticos e ácido base, assim como os efeitos de repositores eletrolíticos em diferentes espécies. Entretanto, a literatura ainda carece de informações mais precisas e menos subjetivas a respeito dos parâmetros e determinação da desidratação em bovinos adultos. O objetivo geral desse estudo foi avaliar os principais parâmetros clínicos e laboratoriais de bovinos adultos desidratados experimentalmente. Foram utilizados dez bovinos, fêmeas, mestiças de raças leiteiras, hígidas, não gestantes e apresentando bom escore corporal, apresentando peso corporal entre 235 e 591 quilogramas. Como protocolo de desidratação, utilizou-se unicamente as restrições hídrica e alimentar, durante 72 horas, sendo as avaliações clínica e laboratorial realizadas a cada 8 horas. Esse protocolo demonstrou ser eficiente para promover desidratação intensa, que foi mais bem indicada pelos parâmetros: enoftalmia, umidade do muflo, avaliação da umidade e coloração das mucosas, tempo de enchimento capilar (TEC), turgor cutâneo, concentração de ureia (UN), densidade urinária e teor de umidade das fezes, porém o tempo de desidratação fez com que alguns parâmetros, como os hemogasométricos, por exemplo, não fossem alterados. Os indicadores mais confiáveis para determinar a desidratação no presente trabalho, foram: enoftalmia, umidade do muflo, avaliação da umidade e coloração das mucosas, tempo de enchimento capilar (TEC), turgor cutâneo, concentração de ureia (UN), densidade urinária, teor de umidade das fezes e proteína plasmática total. O presente trabalho possibilita a atualização dos parâmetros indicadores de desidratação em bovinos adultos mestiços de raças leiteiras. Palavras-chave: Desequilíbrio hidroeletrolítico. Enoftalmia. Hipovolemia. Vacas de leite.
Nursing Internship; a challenge on the door step
Authors: Amir Sultan
Published: June 2023

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NANOCRINOLOGY
Authors: Sanjay Kalra  , Saptarshi Bhattacharya  , Atul Dhingra
Published: June 2023

We conceptualize and define nanocrinology as the science that studies the nanometric and subnanometric precision that operates in diagnostic and therapeutic endocrinology. It includes advanced generation assays, which can detect low concentrations of hormones, and modern drug delivery systems that allow more efficient delivery of endocrinotropic agents. Nanocrinology is a rapidly growing field of endocrinology, and we call for greater research and adoption of this science.

Keywords: Diagnosis, endocrinology, hormone, radioimmunoassay, nanoformulation.
Sodium Literacy
Authors: Sanjay Kalra  , Bharti Kalra  , Nitin Kapoor
Published: June 2023

This communication describes the concept of sodium literacy as means of optimizing sodium intake and achieving better cardiovascular health. It also highlights the sources of sodium in South Asian cuisine which can be avoided or minimized.

Keywords: Cardiovascular disease, diet, hidden hunger, malnutrition, salt.
Bariatric Triage: Weight Loss As A Tool For Therapeutic Decision Making
Authors: Sanjay Kalra  , Jubbin Jacob  , Nitin Kapoor
Published: June 2023

This communication highlights how early weight loss can be used as a technique for triage in persons who have undergone bariatric surgery, and as a tool for therapeutic decision making. Weight loss is a target for obesity medicine, but can also be used to plan further treatment strategies and interventions. In this manner, early weight loss is similar to HbA1c (glycated haemoglobin) which is a diagnostic tool, a monitoring device, a therapeutic target, and also a technique to decide intensity of treatment in diabetes.

Keywords: Bariatric triage, barocrinology, metabolic, adaptation, obesity, overweight.
Tumour sink effect on 68Ga-PMSA PET/CT: A case of diffuse metastatic disease of prostate cancer
Authors: Sharjeel Usmani  , Khulood Al Riyami  , Sofiullah Abubakar  , Anjali Jain  , Asiya Al Busaidi
Published: June 2023

68Ga-PMSA imaging has revolutionized both diagnosis and radioligand therapy selection in patients with metastatic prostate cancer. We report a case of a 59-year-old recently diagnosed prostate cancer with high PSA level pf >2000ng/ml referred for 68Ga-PSMA PET/CT. 68Ga-PSMA PET/CT showed diffuse intense tracer uptake throughout the axial and appendicular skeleton with significantly lower uptake of 68Ga-PSMA in normal organs in a configuration of “tumour sink effect”. Findings are in keeping with diffuse skeletal infiltration and suspected marrow infiltration. Given the extensive nature of bone disease and pattern, 177Lu-PSMA-targetted radioligand therapy was thought to be more appropriate in a given situation with a favourable toxicity profile.
Keywords: 68Ga-PSMA PET/CT; tumor sink effect; 177Lu-PSMA-RLT; PET/CT
1st International Conference on Biomedical Sciences, Dow University of Health Sciences, Karachi Pakistan
Authors: Zeba Haque  , Farina Hanif  , Muhammad Owais  , Sonia Siddiqui
Published: June 2023

Institute of Biomedical Sciences (IBMS) at Dow University of Health Sciences (DUHS), organised a two day’s conference on Biomedical Sciences. IBMS being the part of one of the largest public sector health universities of Pakistan, is now transforming the research trends to be effectively translated at the community level. Currently with a strong PhD faculty line in basic and clinical sciences, DUHS has a significant contribution in research output of the country. The scientific data however represents a small population per scientific study and the generalization of results may not be inferred. It must be extended through translational research for effectiveness. The conference was planned with a theme to bridge the gap between basic and translational research. The two day’s conference conducted in second week of March 2023 at Dow International Medical College Ojha Campus DUHS was able to attract more than 300 participants. The scientific sessions encompassed a vast variety of health issues and their proposed solutions including neurosciences, virtual biopsies, metabolomics, medical writings and incorporation of engineering and artificial intelligence to facilitate detection and prognosis of disease. The conference was able to conclude that the multidisciplinary research studies with collaboration of two or more institutes/organizations are the need of time. Young researchers need an effective platform to showcase their research and make collaborations. Moreover, the incorporation of artificial intelligence would enhance patient care within health systems.
Keywords: Biomedical Sciences, basic research, Translational research, IBMS, DUHS.
Co-administration of saffron and chamomile: to determine the efficacy as an adjuvant therapy for mild to moderate depression in human subjects. A pilot randomized clinical trial
Authors: Saara Ahmad  , Khan Asra , Rafiq Hamna , Tikmani Prashant , Mesiya Hanif , Amin Faiq
Published: June 2023

Objectives: To determine the combined effects of chamomile and saffron herbs as an adjuvant therapy in patients with metabolic alterations associated with mild to moderate depression.
Method: The prospective, randomised, blinded, end-point pilot study was conducted at the Aga Khan University, Karachi, from August to October 2020, and comprised patients with mild to moderate depression with or without diabetes, hypertension and dyslipidaemia. The subjects were randomised into intervention group A, which was given herbal tea sachets containing saffron 1mg and chamomile 20mg for twice a day oral use for a month along with medications, and control group B, which was advised to continue their routine medications. Data was collected at baseline and post-intervention using Patient Health Questionnaire-9 for assessing depression severity, and blood samples for cholesterol estimations. Data was analysed using SPSS 20.
Results: Of the 50 subjects, 25(50%) were in each of the two groups. Cholesterol, high-density lipoprotein, low-density lipoprotein and depression values were significantly better in group A than in group B (p<0.05).
Conclusion: Potential benefits of combined doses of chamomile and saffron were found in depressive patients by improving metabolic alterations.
Key Words: Chamomile, Saffron, Depression, Hyperlipidaemia.
Synovial sarcoma: a rare neoplasm of paranasal sinus
Authors: Abrar Sehrish , Fatima Shaukat  , Muhammad Atif Mansha  , Agha Muhammad Hammad  , Yumna Ahmed  , Nasir Ali
Published: June 2023

Synovial Sarcoma (SS) is a rare soft-tissue malignant tumour. Its presentation in the head and neck region is uncommon. Because of the complex anatomy of the head and neck region, surgery with clear margins is not achievable. In such cases, a multi-modality approach is required as there is no established standard of care. In this report, we share the case of a girl who presented with nasal obstruction. Imaging revealed a mass involving the left nasal cavity, paranasal sinuses without intracranial extension. It was diagnosed as synovial sarcoma. She underwent surgical excision and adjuvant radiation therapy (RT) to the tumour bed, followed by an incomplete course of chemotherapy. Later on, she developed systemic disease. Considering the rarity of this case and lack of guidelines for standard treatment, we report on this case to share our experience with management and treatment outcome.
Keywords: Head and neck region, Synovial sarcoma, Radiotherapy, chemotherapy.
Evaluation of predictive factors of renal function recovery in renal failure secondary to urinary tract obstruction
Authors: Kalwar Sara Rasheed , Mahar Naveed , Lal Murli , Memon Mohsin Mustafa , Qureshi Harris Hassan , Hussain Manzoor
Published: June 2023

Objective: To determine the factors associated with renal function recovery in individuals with kidney failure due to obstruction in the urinary tract.
Method: The prospective, descriptive study was conducted July 2020 to August 2021 at the Department of Urology, Sindh Institute of Urology and Transplantation, Karachi, and comprised adult patients of either gender who had renal failure secondary to obstructive urinary tract. Baseline data regarding patients’ variables, including age, gender, duration of symptoms (25 days or 25 days), haemoglobin (9.85g/dl or 9.85g/dl), serum creatinine and renal cortical thickness (16.5mm or 16.5 mm), was noted on a proforma. The variables were stratified to assess impact on renal recovery. Data was analysed using SPSS 23.
Results: Of the 126 patients, 43(34.13%) were males and 83(65.87%) were females. The overall mean age was 44.13±14.18 years. Renal recovery occurred in 67(78.8%) patients having duration of symptoms 25 days, and in 13(31.7%) patients with duration of symptoms 25 days (p 0.001). Renal recovery occurred in 41(58.6%) patients having haemoglobin 9.85g/dL and in 39(69.6%) patients having haemoglobin 9.85g/dL (p=0.2). Renal recovery occurred in 26(37.7%) patients with parenchymal thickness 16.5mm and in 54(94.7%) patients with renal cortical thickness 16.5mm (p 0.001).
Conclusion: Symptom duration 25 days, and renal parenchymal thickness 16.5mm were found to be predictive factors of good recovery in renal failure cases secondary to obstructive uropathy.
Key Words: Urinary obstruction, Obstructive nephropathy, Percutaneous nephrostomy, Renal failure.
Problem to solution; from mammalian skin grafts to renal allograft rejection: a tale of 66 years of evolution of our understanding
Authors: Dhrolia Murtaza , Ahmad Aasim
Published: June 2023

The first successful kidney transplant was done in 1954, and it remains the best option for those with failed kidneys. However, the recipient’s immune system remains the most formidable barrier to transplantation, leading to rejection. Rejection continues to be the most important reason of graft malfunction and chronic renal allograft dysfunction and remains a challenge to date for successful transplant survival. The current narrative review was planned to find the best possible solution to the problem from among the different solutions presented in literature related to allograft rejection since 1954.
Key Words: Evolution, Renal transplantation, Allograft rejection, Immunosuppressant.
Effect of hybrid blood purification treatment for patients with maintenance haemodialysis
Authors: Zhang Ting , Zhang Cuiping
Published: June 2023

Objective: To investigate the effect of hybrid blood purification treatment on levels of serum molecular toxins, micro-inflammatory mediators and quality of life in maintenance haemodialysis patients.
Method: The analytical study was conducted at the Fifth Affiliated Hospital of Xinjiang Medical University, China, from January 2019 to January 2021, and adult maintenance haemodialysis patients of either gender who were having dialysis at least 3 times per week for at least 4 h each time. The patients were randomised into two equal groups. Group A received pure haemodialysis, while Group B was given hybrid blood purification treatment. Serum parathyroid hormone, Beta 2 microglobulin, high-sensitivity C-reactive protein and interleukin-6 were determined. Kidney disease target areas and short-form 36 scores were compared between the groups. All parameters were assessed at baseline and after 3 months of intervention. Data was analysed using SPSS 25.
Results: Of the 216 patients, 108(50%) were in each of the two groups. Overall, there were 120(55.6%) male and 96(44.4%) female subjects; mean age was 58.50±6.73 years; and mean dialysis duration was 31.92±5.05 months. At baseline, none of the study parameters were significantly different between the groups (p>0.05). Post-intervention, all parameters were lower in Group B compared to Group A (p<0.05).
Conclusion: Compared to haemodialysis alone, hybrid blood purification treatment. I was found to be more effective in removing molecular toxins from haemodialysis patients’ blood, reducing serum micro-inflammatory status, and improving their quality of life.
Key Words: Maintenance haemodialysis, Hybrid blood purification treatment, HBPT, Micro-inflammatory, Quality of life.
Herbal extracts: the future treatment option for drug-resistant epilepsy
Authors: Mehr Musani  , Muhammad Wasim  , Hassan Salman Siddiqi  , Saara Muddasir  , Fazal Manzoor Arain
Published: June 2023

Epilepsy is a neurological disorder characterised by two or more unprovoked seizures. The high prevalence and incidence of epilepsy globally, especially in Asia, has remained a big concern over the course of centuries. Patients are usually prescribed the already known anti-epileptic drugs, but even after going through three different generations of anti-epileptic drugs, some people still suffer from drug-resistant form of epilepsy. These patients are usually prescribed a higher dose of anti-epileptic drugs, which results in more adverse effects. That is why new treatment options, like herbal extracts, should be explored for patients who do not respond to the classic anti-epileptic drugs. The current narrative review was planned to explore if herbal extracts can be the future for the treatment of drug-resistant epilepsy.
Key Words: Epilepsy, Herbal extracts, Drug-resistant epilepsy, Anti-epileptic drugs.
Another way to successfully remove dialysis catheter misplaced into subclavian artery through right internal jugular vein: case report
Authors: Li Xiaodong , Yancong Guo
Published: June 2023

For haemodialysis in patients with uraemia, catheterization of the internal jugular or femoral vein is often required to establish access. Puncture with catheterization in the right internal jugular vein (RIJV) is relatively simple, and thus, is the appropriate choice for haemodialysis. However, catheterization at this site can lead to complications, including bleeding at the puncture site. Moreover, in several cases, the haemodialysis catheter (HDC) can be misplaced in the internal carotid artery and subclavian artery, thus making the management troublesome later on. In this article, we report the case of a middle-aged female patient with uraemia wherein a temporal HDC was misplaced into the right subclavian artery during right internal jugular vein catheterization. Instead of conventional surgery and endovascular intervention, the catheter was left in that place for four weeks and subsequently removed directly, followed by local compression for 24 hours.
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