bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the Molecular Interactions of Potassium Chloride Solutions in N-Methylmorpholine by Physical Methods at Different Temperatures
Authors: Saleh Mohammad M. , Al.Azzaawi Soad F. , Khamase Saba M.
Published: October 2024

تم في هذه الدراسة قياس الكثافة، اللزوجة ومعامل الانكسار للمخاليط ثنائية المكون من N-مثيل مورفلين والماء بنسب وزنية مختلفة (%25، %50 و %75) في درجات حرارية 298.15، 308.15 و 318.15 كلفن. تم حساب الحجم المولاري الفائض، VE اللزوجة الفائضة، hE ومعامل الانكسار الفائض، nE لهذه المخاليط.
من النتائج التي تم الحصول عليها لنفس المخاليط والتي تحتوي على ملح كلوريد البوتاسيوم ضمن مدى التركيز (0.0025-0.1 M)، أتضح لنا بأن ملح كلوريد البوتاسيوم يعمل على كسر للتركيب (Structure Breaker) لمخاليط المذيب والماء وفي نفس الوقت يؤدي إلى زيادة التداخل الجزيئي بين أيون الملح والماء وأيون الملح والمذيب، وهذا واضح من قيم معامل B لمعادلة جونز-دول:
(hrel - 1) /  = A + B
حيث يمثل المعامل A التداخل بين الأيون-الأيون، والمعامل B يمثل التداخل بين الأيون والمذيب،C  تركيز كلوريد البوتاسيوم  حيث عند زيادة تركيز مذيب N-مثيل مورفلين، نجد إن قيم معامل B تقل مما يدل على ان الملح يعمل على بناء التركيب (Structure Maker) لمخاليط الماء والمذيب.
 ومن حسابات طاقة التنشيط للانسياب اللزج DG* وجد ان قيمة طاقة التنشيط تكون أعلى في حالة الخليط الذي يحتوي على نسب متساوية من الماء ومذيب N-مثيل مورفلين.
A study of adsorption in aqueous solution of p,o,m-Chlorophenol on Iraqi siliceouns rocks powder
Authors: Mohammed Ammar J.
Published: October 2024

يتناول البحث دراسة قابلية الأمتزاز لمركبات كلوروفينول من محاليلها المائية على سطح مسحوق الصخور السليسية العراقية.
أستخدمت تقنية الأشعة فوق البنفسجية في تعيين ايزوثيرمات الأمتزاز وبينت النتائج أن ايزوثيرمات الأمتزاز تتبع معادلة فرندلش للامتزاز.
أوضحت النتائج أن عملية الأمتزاز من النوع الماص للحرارة أي أن زيادة درجة الحرارة تؤدي إلى زيادة قابلية الامتزاز, تم حساب H)S, G, ( لعملية الامتزاز. بينت النتائج أن الامتزاز يزداد مع زيادة حامضية المحلول.
II-Preparation and characterization Schiff base Derivatives with some transition metal complexes
Authors: AL- Obaidi Omar Hamad Shehab
Published: October 2024

يتضمن البحث تحضير معقدات لبعض مشتقات قواعد شف( كليكندات) ذات التراكيب التالية :
        ( -2هيدروكسي- بنزيليدين ) - ثايويوريا=(L1)
        ( -2هيدروكسي- بنزيليدين ) - يوريا =(L2)
     تم تحضير معقدات لهذه الليكندات مع بعض املاح العناصر الانتقالية التي تشمل   (Zn+2,Cd+2,Hg+2) وقد تم تشخيص ودراسة تراكيب الليكندات والمعقدات المحضرة باستخدام تقنية التحليل الدقيق للعناصر (C.H.N) ومطيافية الاشعة تحت الحمراء والاشعة فوق البنفسجية وتقنية الامتصاص الذري اضافة الى قياس الموصلية الكهربائية المولارية ودرجات الانصهار للمعقدات المحضرة وعلى ضوء النتائج تم تعيين التركيب الهندسي لهذه المعقدات.
Effect of Pupal Exposure of Raisin Moth ,Ephestia figulilella (Gregson),(Lepidoptera:pyralidae) to High Temperature on Certain Biological Parameters of the Adult
Authors: Shawkit M.A. , Al Taweel A.A , AL-Bahadyli L.J. , Deab N.S. , Khedher N.A. M.
Published: October 2024

عرضت عذارى عثة الكشمش للمدد ( 1 ، 3 ، 6 ساعات ) للدرجات الحرارية ( 40 ، 45 ، 50 ) ْم على التوالي فضلا عن المقارنة التي كانت درجتها الحرارية 28 ْم  أشارت النتائج الى ان البالغات الناتجة من العذارى المعرضة لدرجة حرارة  50 ْم لمدة 6 ساعات وتزاوجهما فيما بينهما او مع الجنس غير المعرض لهذه الدرجة الحرارية كانت عقيمة كليا وان نسبة فقس البيض كانت صفرا مقارنة بنسبة فقس البيض لتزاوج المقارنة التي هي 87 % .
كما بينت النتائج ان عدد الحشرات البالغة المشوه والخارجة من العذارى المعرضة للدرجات الحرارية  وكذلك عدد العذارى الجافة يزداد كلما ارتفعت درجة الحرارة وازدادت مدة التعريض .
Effect of Gamma Radiation on Sterility, Sexual Competitiveness and Mating Ability of Carob Moth Ephestia calidella (Guen.)Irradiated as Pupae
Authors: Ahmad T. R. , Hamad B. Sh. , Barkhi G. S.
Published: October 2024

عند تشعيع عذارى حشرة عثة الخروب وقبل يومين من بزوغ البالغات بالجرع الاشعاعية 0 و100و200 و300 و400 غري فان اعلى نسبة عقم كانت %92  عند تشعيع عذارى الذكور بـ300  غري ولم تختلف معنوياً عند مستوى   0.05تبعاً لاختبار دنكن متعدد الحدود عن التي شععت بالجرع الاشعاعية الاخرى بينما اعلى مستوى من العقم كان %100  عند تعريض عذارى الاناث  للجرعة 400 غري وفي الوقت نفسه فعند تشعيع عذارى كلا الجنسين بالجرع 200 و300و400 غري وتزاوج البالغات البازغة فيما بينها اعطت مستوى من العقم بلغت نسبها  94.4 و98.2 و%99.6  على التوالي، ويبدو واضحاً ان الاناث اقل مقاومة للاشعاع من الذكور. وعند اضافة الذكور المشععة الى الذكور والاناث غير المشععة وبنسبة (1:1:3) فان النسبة المئوية لفقس البيض قلت من 76.4% في المقارنة الى 36.3% للذكور المشععة بجرعة 400 غري وعلى اية حال فان التنافس الجنسي والقابلية على اخصاب الاناث يقل مع زيادة الجرعة الاشعاعية.
Study of efficiency of crude extract of local Horsetail Equiaetum arvense L. in blood coagulation
Authors: Zokian S.A. , Al- Bayati M.KH. , AL.Mawla R. M.
Published: October 2024

أجريت هذه الدراسة على الاجزاء الخضرية لنبات ذنب الخيل المحلي Equisetum arvense L. الذي ينمو طبيعيا في منطقة حاج عمران شمال العراق ، وتضمنت بعض الفحوصات المختبرية التي تتعلق  بعملية تخثر الدم ، باستخدام تراكيز متدرجة من كلا المستخلصين المائي والكحولي خارج الجسم الحي In vitro  وداخل الجسم الحيIn vivo  ، وتبينت فعالية التركيزين (25 و50 ) ملغم / مل للمستخلص المائي لذنب الخيل في تقليل زمن تخثر الدم خارج الجسم الحي غير ان التركيز الاعلى (100) ملغم / مل عمل على سيولة الدم وعدم ثخثره خارج الجسم الحي . كما ظهرت فعالية المستخلص المائي والكحولي في تقليل زمن التخثر، فضلاً عن زيادة عدد الصفيحات الدموية مع زيادة التركيز داخل الجسم الحي، وان التركيز (100) ملغم / مل كان ذا تأثير مخالف عن البقية، إذ  أدى الى زيادة زمن التخثر وسيولة الدم مع نقصان في عدد الصفيحات الدموية.
Spectral study to determine type of oil products and the mixing rates between them
Authors: Al-Hadeethi Assmat. R. , Al-Jumaili Hamid. S. , Sirhan M. M.
Published: October 2024

تم في هذا البحث قياس الامتصاصية الطيفية ضمن المدى (300-700nm) للمشتقات النفطية ومخاليطها وهي (الكازولين, الكيروسين, الكازاويل) وقد شملت نسب الخلط على (0:10, 2:10, 4:10, 6:10, 8:10, 10:10) ومن أشكال الامتصاصية مع الطول ألموجي لكل نسبة استطعنا تحديد مواقع  وقيم قمم الامتصاص ومقارنة المخلوط منها مع غير المخلوط لمشتقات نفط عراقيةلامكانية معرفة نوع المشتق النفطي ونوعية المخلوط والحصول على معرفة كمية الخلط من خلال تحديد مكان وقيمة قمم الامتصاص الطيفية. وقد تبين بان هناك تفاعلات تحدث بين بعض المشتقات النفطية تعطي نوع أخر لا يشابه أي من المخلوطين الأصلية وبالتالي سوف يعطي نتائج سلبية في حالة استخدامه في مكائن الوقود. أما البعض الأخر فقد تغيرت كثافته من خلال عملية الخلط فقط.وتم تفسير النتائج على ضوء الامتصاص الطيفي للمنتجات النفطية.
Distribution of Positron Annihilation Lifetime Components
Authors: Selman Ahmed Abdul-Razzaq , Saeed Muna Ahmed
Published: October 2024

لقد تم توضيح العلاقة بين مركبات طيف فناء البوزترون مع نموذج الحجم الحر، وحسبت النسبة النظرية بين شدة الفناء من الحالة الأحادية (Singlet para state) والحالة الثلاثية (Triplet ortho state) والموصوفة بالمعامل η ومقارنتها مع النسبة المحسوبة من النتائج عمليا، والتي تتبع معادلة وضعية.  وعند تطبيق هذه المعادلة على نتائج عملية وجد أن النسبة المحسوبة من النتائج العملية تقترب من النسبة النظرية، والتي هي 3/1.
بالإضافة إلى ذلك، فقد تم الربط بين نسبة الحجم الحر، Fh, والحجم الحر،Vh، المحسوبة من عمر فناء المركبة الطويلة τ3 مع الثابت C.  وعلى أساس هذا الربط فسرت الأسباب وراء تغير قيم الثابت C وتفاوت قيم المعامل η بين القياسات المختلفة وربط ذلك مع النسبة النظرية للمعامل  η. تم اقتراح نموذج انتشار الشدة لتفسير النتائج عند استخدام مطيافية فناء البوزترون لتفسير هذه التصحيحات.
Determination of Desferrioxamine in the Drug Desferal™ as DFOM-Au (III) Complex by Using Indirect Electrothermal Atomic Absorption Spectrometry and Other Techniques.
Authors: AL-Ayash Ashraf.S. , Khammas Zuhair A-A , Jasim Fadhil
Published: October 2024

استحدث طريقة تحليلية غير مباشرة لتعيين المادة الفعالة الدسفيروكسامين في دواء الدسفرال من خلال تفاعل هذا المركب مع عنصر الذهب الثلاثي لتكون معقد مخلبي يجري استخلاصه بمذيب رابع كلوريد الكربون وحقن حجم معيين من هذا المستخلص في الفرن الغرافيتي المطلي بكربيد الزركونيوم . جرى دراسة معرفة تكوين وتركيب المعقد DFOM-Au(III)) بالتقنيات المعروفة مثل مطيافية الاشعة تحت الحمراء ومطيافية الاشعة الفوبنفسجية-المرئية وتبين ان النسبة المولية للعضيدة-الفلز هي 1:1.
لقد تم دراسة العوامل التجربية التي تؤثر على تكوين هذا المعقد من خلال حساب الممتصية الذرية بالفرن الكرافيتي للحصول على الظروف الامثلية . كما تم تثبيت ارقام الاستحقاق التحليلية (figures of merits ) من منحنيات المعايرة كالمدى الخطي والحساسية وحد الكشف ونسبة الاسترداد بالمائة والدقة المعبر عنها بالاستنساخيه . جرى تطبيق هذه الطريقة لتعيين الدسفيروكسامين في دواء الدسفرال ووجد ان تركيزه هو 488 و 484 ملغم / وحدة في هذا الدواء باستعمال المعايرة المباشرة واضافات القياس على التوالي مقارنة بالكمية المصرحة على العبوة وهي 500 ملغم / وحدة .
 كانت نتائج مطيافية الامتصاص الذري غير المباشرة ومطيافية الاشعة الفوق البنفسجية-المرئية المباشرة متفقة إذ نفذت معظم الحسابات الاحصائية باستخدام البرنامج الحاسوبي (Minitab version 11) .
Modeling of Mixing Time for Bioreactors with Self-Inducing Impellers
Authors: M. Alaa   K.
Published: October 2024

يعد زمن الخلط احد اهم العوامل المهمة في تحديد كفاءة الخلط للاوساط الغذائية في المفاعلات الحيوية وكذلك في عمليات توسيع الانتاج. يعتمد هذا الزمن على طبيعة الوسط الغذائي والظروف التشغيليةللعملية التحضيرية وكذلك على الشكل الهندسي للخلاط المستخدم في عملية المزج. استخدم في هذا البحث ملح صوديوم كاربوكسي مثيل سليلوز كمادة مشابهة للوسط الغذائي ذات التخمر الهوائي وتمت دراسة تاثير كل من لزوجة الوسط الغذائي ، سرعة تدوير الخلاط والشكل الهندسي للخلاط على زمن الخلط . استخدم لهذا الغرض مخمر ذات الخلاط الساحب للهواء. تم تحليل النتائج العملية للبحث رياضيا باستخدام برنامج MATLAB بهدف الحصول على موديل رياضي يربط  زمن الخلط مع العوامل  المذكورة اعلاه في مدى من رقم رينولد اصغر من  5000(Re<5000) وهو المدى الشائع لتشغيل المفاعلات الحيوية للاغراض الصناعية.               
اعطت هذه المعادلة تطابق جيد مع النتائج العملية المستحصلة من البحث  وبمعدل حيود .6.6%
SYNTHESIS,ANTIBACTERIAL ACTIVITY OF 2-AMINO 5-PHENYL -1,3,4- OXADIAZOLE DERIVATIVES
Authors: Mohammed Hussain jassem
Published: October 2024

في هذا البحث تم تحضير خمسة مشتقات لمركب 2 –أمينو فنيل-4,3,1 –أوكسادايازول ذات فعالية كمضادات بكتيرية. المركبات المحضرة هي 2 –أمينو فنيل-4,3,1 –أوكسادايازول ثنائي ثايوكربمات , 2 –أمينو5 –(4 –أمينو-N,N –ثنائي مثيل فنيل)-4,3,1 –أوكسادايازول ,  2 –أمينو5 –(4 –أمينو-N,N –ثنائي مثيل فنيل)-4,3,1 –أوكسادايازول ثنائي ثايوكربمات , 2 –أمينو5 –(4 –نايترو فنيل)-4,3,1 –أوكسادايازول , 2 –أمينو5 –(4 – نايترو فنيل)-4,3,1 –أوكسادايازول ثنائي ثايوكربمات . تم دراسة هذه المركبات كمضادات للبكتريا والفطريات وكانت النتائج الفعالية البايولوجية للمركبات واضحة كمضادات للانواع المدروسة كما تم تشخيص المركبات المحضرة بوساطة أطياف الاشعة تحت الحمراء وأطياف الرنين النووي المغناطيسي وبعض الخواص الفيزيائية لها.
The use of wastewater and inorganic fertilizers as nutrients source for cultivation of diatom Nitzschia palea
Authors: Al-Saadi Hussain A. , Kassim Thaer I. , Al-Hassany Jennan S.
Published: October 2024

استخدم نوعين من الأوساط الغذائية البديلة (مياه الصرف الصحي والأسمدة الزراعية اللاعضوية) لاستزراع الديتوم Nitzschia palea(Kuetz.)W. Smith . خلطت هذه الأوساط بنسبة 50% مع الوسط الغذائي الصناعي Chu-10 المحور في ظروف مسيطر عليها (درجة الحرارة 25 ºم وشدة الإضاءة 260 مايكروانشتاين/م² /ثا). أظهرت دلائل النمو للديتوم ان أعلى معدل نمو بلغ 0.56 خلية/ساعة وأقل زمن تضاعف 13 ساعة للوسط المكون من 50% من مياه الصرف الصحي مع مثلها من الوسط Chu-10 . جاء بعدها  وسط  الأسمدة  الزراعية المسمى N:P:K" " بتركيز 125 ملغم/لتر (نيتروجين:فسفور:بوتاسيوم) وتركيز 12.5 ملغم/لتر من الوسط المكون من السوبرفوسفات P2O5  و100 ملغم/لتر من كبريتات المغنيسيوم و10 ملغم/لتر من سليكات الصوديوم والتي أعطت معدل نمو قدره 0.35 خلية/ساعة وزمن تضاعف بلغ 20.7 ساعة وعدد خلايا 9.75 × 106 خلية/مليلتر وامتصاصية 0.86 نانوميتر، وعلى هذا الأساس ممكن الاستفادة من مياه الفضلات والأسمدة الزراعية اللاعضوية كونها أوساطاً بديلة لتنمية هذا النوع من الطحالب مع الأخذ بنظر الإعتبارسهولة الحصول عليها لخفض كلفة الاستزراع في الأوساط الزراعية الصناعية.
Experimental study on the influence of different curing methods on the performance of concrete
Authors: Guo Guohe , Zhao Shangchuan , Wen Dongchang , Zhang Ge , Liu Longlong
Published: October 2024

Curing concrete is an effective method to ensure concrete’s mechanical and durability performance. This article experimentally investigates the impact of various curing methods (air curing, sprinkler curing, geotextile curing, and composite geotextile curing) on the compressive strength of concrete at 7, 14, and 28 days, as well as the carbonation depth and chloride ion diffusion coefficient at 28, 56, and 90 days. The effects of different curing methods on concrete performance are compared. The experimental results demonstrate that sprinkler, geotextile, and composite geotextile curing at 7 and 14 days effectively enhance concrete’s mechanical and durability performance. Compared to air curing concrete at 28 days, sprinkler, geotextile, and composite geotextile curing reduced by 17.75 %, 25.11 %, and 31.51 %, respectively, but the average absolute deviation is reducing. From 28 to 90 days, air curing concrete’s chloride ion diffusion coefficient decreases by 8.5 %. For concrete specimens under sprinkler curing, geotextile curing, and composite geotextile curing, the chloride ion diffusion coefficient decreases by 20.4 %, 8.3 %, and 6.0 %, respectively. Beyond 28 days, the durability performance of concrete under composite geotextile curing, including carbonation depth and chloride ion diffusion coefficient, tends to stabilize. The optimal curing period of 28 days is determined based on comprehensive mechanical and durability performance. Composite geotextile curing retains moisture on the concrete surface, slows evaporation, reduces watering frequency and labour costs, and promotes long-term concrete performance development. Carbonation tests and durability performance, such as chloride ion diffusion coefficient, are more sensitive to concrete curing effects. Single indicators like mechanical or durability performance cannot comprehensively evaluate concrete’s long-term performance. Concrete quality should be comprehensively evaluated by considering strength, carbonation depth, chloride ion diffusion coefficient, and other indicators.
A study on active structural acoustic control using force radiation modes
Authors: Mao Rongfu , Zhu Haichao , Gao Shanping , Zhang Xing
Published: October 2024

Active Structural Acoustic Control (ASAC) is an effective method for sound radiation control. To solve the coupling effect or inconvenience problems existed in the application of conventional methods, by utilizing the characteristic of intuitive representation of radiated sound power through force radiation modes, the control forces are designed to make the total excitation force vector orthogonal to each dominant force radiation mode. Therefore, an ASAC method by utilizing force radiation modes is proposed, and detailed theoretical research and numerical calculation analysis are carried out. The research results indicate that the control force requirement can be intuitively obtained through the force radiation modes, and decoupled control of radiated sound power corresponding to each force radiation mode is achieved by the proposed method. Thus, the control strategy and system construction can be greatly simplified, and structural acoustic radiation can be effectively controlled.
Optimization of atomization performance of external mixing air atomizing nozzle based on response surface agent model
Authors: Sun Zegang , Zheng Zhonghao , Zhang Jiabin , Zhao Fan
Published: October 2024

Based on the finding that the atomization performance of the nozzle is affected by its structural parameters, a combination of finite element analysis and structural optimization calculations is used. Finite element analysis was performed through the VOF (Volume of Fluid) module of Fluent software to determine the structural parameters affecting the performance of the atomizing nozzle. The liquid cyclone tank inclination, the length of the flat section at the gas outlet, and the mixing chamber outlet diameter were used as optimization factors. The atomization cone angle and fuel atomization circumferential distribution uniformity index were used as the evaluation indexes of atomization performance. An orthogonal experimental design was carried out based on the above. Proxy model for atomization cone angle and fuel atomization circumferential distribution uniformity index based on response surface method. The optimal structure of the nozzle was obtained by optimization calculation of the agent model by genetic algorithm. The results show that the atomization performance is optimal when the inclination angle of the liquid rotating tank is 42.9, the length of the flat section at the gas outlet is 3.3, and the diameter of the mixing chamber outlet is 5.0. The atomization cone angle increased by 23.07 % compared with the original model, and the fuel atomization circumferential distribution uniformity index decreased by 45.06 %. A new solution for the design of externally mixed air atomizing nozzles is provided.
Fault diagnosis of rolling bearing under complex working conditions based on time-frequency joint feature extraction-deep learning
Authors: Ma Zhiguo , Guo Huijuan
Published: October 2024

The same independent distribution is not obeyed for the data collected under complex working conditions such as time-varying speed or loading, and the fault characteristic information is insufficient, resulting in low accuracy by using traditional methods. To solve the above problem, a fault diagnosis method based on time-frequency joint feature extraction combined with deep learning is proposed. Firstly, the original vibration signal is processed by variational mode decomposition (VMD) to obtain several intrinsic mode functions (IMFs), then the sensitive components are selected by calculating the steepness values of each IMF. Subsequently, the characteristic features of the selected sensitive component in time-domain, frequency-domain and time-frequency domain are calculated to form the time-frequency joint feature. The sparse attention mechanism (SAM) is combined with the advantages of recurrent neural network (RNN) and convolutional neural network (CNN) to form a hybrid deep learning model (SAM-RNN-DCNN). Finally, the time-frequency joint features are combined with the hybrid model for fault diagnosis. Experimental verifications are carried out by using data sets under variable rotational speed, variable load and strong noise interference, and the analysis results show that the proposed method has high diagnostic accuracy, good diagnostic performance and robustness under complex working conditions.
Optimizing water usage through an automatic garden sprinkler system: Enhancing efficiency and sustainability in gardening
Authors:   Graduate School, Nueva Ecija University of Science and Technology, Cabanatuan, Philippines, Jacoba Feliciana P.
Published: October 2024

This study investigates the design and operation of an automatic garden sprinkler system, focusing on the need for a dependable, self-operating watering solution that conserves water and supports night-time watering schedules. The research method included a detailed evaluation of the system's performance over 30 days, analyzing data on timing accuracy, water distribution efficiency, and user feedback. The results show that the system works accurately, starting watering cycles within minutes of the set time and efficiently distributing water evenly across the garden. The findings suggest the system can help reduce water waste, supporting global sustainability goals. Additionally, its flexibility and ease of use suggest it could be popular with gardeners and widely adopted. This research adds to the conversation on sustainable gardening and provides insights into using advanced technology in traditional gardening practices.
Collecting Feedback From Neurologists and Patients to Guide Development of a Parkinson Disease App (DigiPark): Qualitative, Noninterventional Study
Authors: Duracinsky Martin , Brown Hajdukova Eva , Péretz Fabienne , Sauzin Julie , Gouider-Khouja Neziha , Atlani Caroline , Dalili Djamchid
Published: October 2024

Background

Parkinson disease (PD) is a worldwide, fast-growing, progressive neurodegenerative condition. Its multifaceted clinical presentation includes a wide range of motor and nonmotor symptoms. Smartphones present a potential solution to better monitor and subsequently alleviate PD symptoms.

Objective

The aim of this study is to explore neurologists’ and patients’ needs and preferences regarding the design and functionality of a new smartphone app for PD, DigiPark.

Methods

This qualitative, noninterventional study gathered data through two primary methods: (1) by conducting interviews with 9 neurologists and (2) through a usability test including 5 patients with PD.

Results

The neurologists affirmed the necessity for a patient-centered app, highlighting the complexities of PD management. They advocated for personalized app functionalities to improve patients’ quality of life and emphasized the need for enhanced patient-provider communication. Feedback from the usability test indicated a preference for a clear, simple user interface, as well as elucidation of the app’s benefits. Concerns about the app’s time demands and the complexity of certain features like medication management were expressed. Furthermore, patients with PD consistently showed interest in features that could track and monitor their progress over time. This highlights the need to include clear benefits within the app to maintain user engagement and commitment.

Conclusions

Neurologists’ and patients’ feedback on the design and functionality of the app complement each other. Collaborative efforts in shaping the app should better address genuine PD management needs. Future clinical trial inclusion can further validate the efficacy of DigiPark.
Temporary Telemedicine Policy and Chronic Disease Management in South Korea: Retrospective Analysis Using National Claims Data
Authors: Kang Ji Ye , Jung Weon , Kim Hyun Ji , An Ji Hyun , Yoon Hee , Kim Taerim , Chang Hansol , Hwang Sung Yeon , Park Jong Eun , Lee Gun Tak , Cha Won Chul , Heo Sejin , Lee Se Uk
Published: October 2024

Background

Since its introduction, telemedicine for patients with chronic diseases has been studied in various clinical settings. However, there is limited evidence of the effectiveness and medical safety of the nationwide adoption of telemedicine.

Objective

This study aimed to analyze the effects of telemedicine on chronic diseases during the COVID-19 pandemic under a temporary telemedicine policy in South Korea using national claims data.

Methods

Health insurance claims data were extracted over 2 years: 1 year before (from February 24, 2019, to February 23, 2020) and 1 year after the policy was implemented (from February 24, 2020, to February 23, 2021). We included all patients who used telemedicine at least once in the first year after the policy was implemented and compared them with a control group of patients who never used telemedicine. The comparison focused on health care use; the medication possession ratio (MPR); and admission rates to general wards (GWs), emergency departments (EDs), and intensive care units (ICUs) using difference-in-differences analysis. A total of 4 chronic diseases were targeted: hypertension, diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), and common mental disorders.

Results

A total of 1,773,454 patients with hypertension; 795,869 patients with DM; 37,460 patients with COPD; and 167,084 patients with common mental disorders were analyzed in this study. Patients diagnosed with hypertension or DM showed increased MPRs without an increase in GW, ED, or ICU admission rates during the policy year. Moreover, patients in the DM group who did not use telemedicine had higher rates of ED, GW, and ICU admissions, and patients in the hypertension group had higher rates of GW or ICU admissions after 1 year of policy implementation. This trend was not evident in COPD and common mental disorders.

Conclusions

The temporary telemedicine policy was effective in increasing medication adherence and reducing admission rates for patients with hypertension and DM; however, the efficacy of the policy was limited for patients with COPD and common mental disorders. Future studies are required to demonstrate the long-term effects of telemedicine policies with various outcome measures reflecting disease characteristics.
Acceptance of Virtual Reality in Trainees Using a Technology Acceptance Model: Survey Study
Authors: Wang Ellen Y , Qian Daniel , Zhang Lijin , Li Brian S-K , Ko Brian , Khoury Michael , Renavikar Meghana , Ganesan Avani , Caruso Thomas J
Published: October 2024

Background

Virtual reality (VR) technologies have demonstrated therapeutic usefulness across a variety of health care settings. However, graduate medical education (GME) trainee perspectives on VR acceptability and usability are limited. The behavioral intentions of GME trainees with regard to VR as an anxiolytic tool have not been characterized through a theoretical framework of technology adoption.

Objective

The primary aim of this study was to apply a hybrid Technology Acceptance Model (TAM) and a United Theory of Acceptance and Use of Technology (UTAUT) model to evaluate factors that predict the behavioral intentions of GME trainees to use VR for patient anxiolysis. The secondary aim was to assess the reliability of the TAM-UTAUT.

Methods

Participants were surveyed in June 2023. GME trainees participated in a VR experience used to reduce perioperative anxiety. Participants then completed a survey evaluating demographics, perceptions, attitudes, environmental factors, and behavioral intentions that influence the adoption of new technologies.

Results

In total, 202 of 1540 GME trainees participated. Only 198 participants were included in the final analysis (12.9% participation rate). Perceptions of usefulness, ease of use, and enjoyment; social influence; and facilitating conditions predicted intention to use VR. Age, past use, price willing to pay, and curiosity were less strong predictors of intention to use. All confirmatory factor analysis models demonstrated a good fit. All domain measurements demonstrated acceptable reliability.

Conclusions

This TAM-UTAUT demonstrated validity and reliability for predicting the behavioral intentions of GME trainees to use VR as a therapeutic anxiolytic in clinical practice. Social influence and facilitating conditions are modifiable factors that present opportunities to advance VR adoption, such as fostering exposure to new technologies and offering relevant training and social encouragement. Future investigations should study the model’s reliability within specialties in different geographic locations.
Efficient Near-Infrared Quantum Cutting in Y2O3 co-doped with Ho3+, Yb3+ Phosphor for the Application in Solar Cell
Authors: Chauhan Prince
Published: October 2024

Abstract: Every aircraft produces wake turbulence during flight. This process arises from the production of lift, resulting in the formation of two counter-rotating vortices trailing behind the aircraft. The vortices can significantly impact encountering aircraft due to their stability, direction duration and strength.
Automatic Noise Monitor and Control in Library
Authors: Deshmukh Yash , Donde Aatish , Jadhav Vishal , Bhill Shubham , Dhase Karan
Published: October 2024

Abstract: This paper introduces imperative to sustain a study-friendly atmosphere in libraries, as noise levels can greatly influence patron satisfaction. In order to reduce noise levels in libraries, this project suggests designing and implementing an autonomous noise monitoring and control system. The device constantly measures ambient noise levels by comparing them to predetermined thresholds using sound sensors and an Arduino. The technology reminds users to keep the environment quiet by sounding alerts and displaying visual cautions when acceptable limits are exceeded. To further reinforce silent norms, automatic audio announcements can be incorporated.
Beyond The Basics: A Detailed Survey of Advanced Python Applications and Innovations
Authors: Pitroda Piyush D. , Donga Bhavika C. , Domadiya Dr. Hasmukh B. , Domadiya Dr. Dipti H.
Published: October 2024

Abstract: Python is the general purpose, high-level, scriptable, interpreted, object oriented and easy to learn language was developed by Guido van Rossum. Python is a popular programming language because of its simplicity, ease of use, open-source licensing, and accessibility. It provides various libraries and frameworks for learning and real world programming. Python’s versatility and active community make it an ideal language for Machine Learning, Data Science, Artificial Intelligence, Networking, Game Development, Web Development and various other domains. In this paper, we will provide an introduction to the main Python programming software tools used for Web development, Data science, Machine learning techniques, Educational Development, etc. In this paper will first introduce Python as a language, and give introduction about Web Development, Data science, Machine learning, Educational Development & Financial Analysis and then describe packages that are popular in that sector
Efficient Near-Infrared Quantum Cutting in Y2O3 co-doped with Ho3+, Yb3+ Phosphor for the Application in Solar Cell
Authors: Malviya Nidhi , Chouhan Vinita , Rawat Shilpi , Khan Nazish
Published: October 2024

Abstract: An efficient Near-Infrared Quantum Cutting has been demonstrated in Ho3+ and Yb3+ co-activated Y2O3 sample, synthesized by a complex based precursor solution method. The phosphors have been characterized by X-ray diffraction (XRD), Crystal structure photoluminescence (PL) and CIE Chromaticity analysis. The phosphor materials give efficient emission in the green region both through UC and PL, while efficient NIR emission is observed through the QC process. The Photoluminescence emission (PL) spectra of Y2O3 doped 1% Ho3+ x% Yb3+ (x= 0, 5, 10, 20, 30, and 50) samples, The cooperative energy transfers from one Ho3+ to two Yb3+, an intense NIR emission around 549 nm of Yb3+ 2F5/2 - 2F7/2 transition was obtained under 449 nm excitation. Near infrared photons (wavelength range 549 nm) emitted by an Yb3+ ion pair. The Properties of Y2O3 doped with Ho3+ and Yb3+ quantum-cutting phosphors are dependent on various factors such as dopant concentration, crystallinity, homogeneity, particle size. Effective control of the above parameters the quantum-cutting ability of the phosphor material. Small particle size of the quantum-cutting phosphor Y2O3:Ho3+, Yb3+ make it a suitable candidate for its application in solar cells.
The Co-Sponsor in the conduct of a Clinical Trial in Germany
Authors: Ahmed Raees , Süngü Simge , Gerst Christoph
Published: October 2024

The sponsor is highly relevant in the conduct of clinical trials, both from a financial point of view and in terms of responsibility for study management. Until now, only one sponsor was designated as the primary contact for the conduct of clinical trials. The new regulation (EU) No 536/2014 allows the use of multiple sponsors, so-called co-sponsors. But this also raises new problems and questions for existing contracts and new contracts between sponsors, especially regarding the liability of one or more co-sponsors in the external as well as the internal relationship. This article highlights the issues arising from this amendment and clarifies the differences between a sponsor and a co-sponsor.
Medical Foods for the management of Chronic Illness and their Regulations in India, US and European Union
Authors: Saxena Trapti , Yadala Sruthi , Sri Ausali Kavya , Reddy Pishati Manasa , Nijhawan Monika
Published: October 2024

As many chronic illnesses are incurable and require repeated treatments, this problem contributes to long-term drug use. But when it comes to managing and treating chronic illnesses, medical foods can provide an alternative to natural medications. Medical foods are foods that have been particularly prepared to meet the unique dietary needs of people with specific illnesses. When it comes to therapeutic applications such as deglutition, dyspepsia, or eating disorders, they are crucial in providing patients with nutritional support. In addition, they significantly improve patients' quality of life by lowering drug use, averting problems that could result from an excessive reliance on pharmaceuticals, and saving treatment costs. Depending on the illness, medical foods' nutritional content can be adjusted and customized. They are exempt from laws pertaining to drugs since they are not drugs. Every medical food is created especially for the chronic condition in question. As a result, the purpose of this review is to clarify the use of medical foods for conditions such as Parkinson's, Alzheimer's, anxiety and sleep disorders, pain syndrome, cancer, congenital metabolic disorders, and diabetes mellitus, and to suggest their use as a dietary supplement for these long-term illnesses.
Comparative evaluation of Food for Special Dietary Use (FSDU) and Food for Special Medical Purpose (FSMP) product regulatory framework in India, EU and US
Authors: Patel Aashvi , Zaveri Maitreyi , Dubey Vishal , Kheni Dharmesh , Kanaki Niranjan
Published: October 2024

Nutraceuticals are naturally occurring compounds that is used globally due to its varied health benefits that extends beyond to basic nutrition. Various types of compounds are included in the umbrella term of nutraceuticals, including vitamins, minerals, herbal extracts, and dietary supplements. For better understanding and defined use of specific nutraceuticals in specific conditions, nutraceuticals are classified into various types, including Foods for Special Medicinal Purpose (FSMP) and Foods for Special Dietary Use (FSDU). FSMP are foods or nutraceuticals that are formulated in such a way to meet specific nutritional needs for managing medical conditions. FSMPs are designed to complement medical treatments, aiding in recovery, and improving quality of life. FSDU are formulated to meet the nutritional needs of individuals with specific dietary requirements or restrictions. FSDU are essential for ensuring individuals receive adequate nutrition while adhering to dietary restrictions. The regulatory framework for FSDU and FSMP varies significantly between countries. Each country has its own set of laws and regulations governing the production, labelling, and distribution of these products. These regulations ensure that FSDUs and FSMPs meet specific safety, efficacy, and nutritional standards relevant to local health policies and consumer protection laws. The review aimed to compare the regulatory frameworks for FSMP and FSDU across India, the US, and the EU. It focused on understanding differences in regulatory requirements for these products in each jurisdiction. By analyzing these regulatory landscapes, the study sought to highlight variations that impact manufacturers, healthcare providers, and consumers in these regions.
Regulatory Development, Adoption, and Perseverance of Real-world Evidence with global health authorities
Authors: Gandhi Sanyam , Saxena Kinshuk , Kartikeyan C , Tiwari Akhilesh , Jain Sachin , Jain Vikas , Pal Pradeep
Published: October 2024

Real-world evidence (RWE) has gained significant attention as a valuable source of evidence in healthcare decision-making. This article provides a comprehensive analysis of the regulatory development, adoption, and perseverance of RWE with global health authorities, as well as a synopsis of the major trends and practices among global health authorities. The aim is to shed light on the current landscape, and prospects of utilizing RWE in regulatory processes. Globally, many health authorities are drafting guidelines for RWE and implementing various regulations. Implementation is in the initial stages because RWE has certain limitations. This article examines the experiences of selected global health authorities in the development and implementation of RWE strategies. It also examines regulatory guidelines, pilot programmes, and collaborations designed to establish a solid foundation for the use of RWE.  However, despite all challenges and limitations, RWE is widely being used in drug approval and commercial sense.
Lifecycle Management of Generic product in US market
Authors: Dhawad Sakshi , Dhote Samiksha , Shegokar Yash , Kale Vinita , Umekar Milind
Published: October 2024

In the US Market, lifecycle management for generic products includes developing and implementing plans to maximize an item’s market potential from launch to decline. It starts with market research and approval of regulatory involving submission of an Abbreviated New Drug Application (ANDA) to demonstrate bioequivalence to the branded product followed by comprehensive market analysis to identify opportunities and assess rivals. Companies use aggressive pricing and marketing techniques to swiftly increase their market share after a product is approved. Continuous monitoring and adaptability to changes in the market, updates to regulations, and competitive actions are crucial throughout the lifecycle. This review focuses on Market entry strategy, Product launch, Market landscape of Generic Drugs in US.
Index of application status transparency and availability of public information for Project Orbis agencies
Authors: Lee Sso H. , Hotaki Lauren T. , Oh Kukhwa , Samuel Jessica , De Villiers Krystal , Eshetie Kirubel , Looi Yee H. , Atiek Eiman , Cudre-Mauroux Fanny , Rohr Ulrich-Peter , Searle Graham , Santos Lenardo N. , Da. S. Andreoli Silmara C. , Aoi Yoko , Hirata Masakazu , Voltz-Girolt Caroline , Aicardo Carlos , Cain Callan , Naggan Tal , Boehm-Cagan Anat , Hirsch-Vexberg Michal , Luxenburg Osnat , Ahmed Nabbiya , Johnson Laura , Hunt Melissa , Vu Duc , Theoret Marc R. , Spillman Dianne , De Claro R. Angelo
Published: October 2024

The purpose of this paper is to provide a guideline for understanding and comparing the regulatory framework of Project Orbis Partners (POPs) and Project Orbis observers, with a focus on their approaches to drug approvals, rejections, and withdrawals. While each agency has its own regulatory framework and guidance, there are some similarities and differences between the language used to describe drug approvals, rejections, withdrawals, and the public availability of these decisions. Project Orbis is an international partnership of regulatory agency, led by the U.S. Food and Drug Administration (FDA), aimed at streamlining the submission and review processes to expedite the global availability of oncology medications for patients. Since its inception, Australia’s Therapeutic Goods Administration (TGA), Brazil’s National Health Surveillance Agency (ANVISA), Canada’s Health Canada (HC), Israel’s Ministry of Health (IMoH) Medical Technologies, Health Information, Innovation and Research (MTIIR) Directorate, Singapore’s Health Sciences Authority (HSA), Switzerland’s Swissmedic (SMC), and United Kingdom’s Medicines and Healthcare Products Regulatory Agency (MHRA) have joined and become POPs. Other international agencies such as, the European Medicines Agency (EMA) and Japan’s Pharmaceuticals and Medical Devices Agency (PMDA) are currently observing Project Orbis, as of late 2023. They are not full Project Orbis partners but work closely with the FDA to facilitate oncology drug approval through international collaboration.
Running Title: An Index of the FDA and international regulators involved in Project Orbis looking at the similarities and differences between approval, rejection, and withdrawal characteristics of applications and public transparency of actions.
Navigating Regulatory requirements for Stem Cells Therapy- A review on Regulations of US, European Union, Japan and India
Authors: Khabade Aishwarya M. , Agarwal Shruti S. , Mahajan Harshali B. , Mandlik Satish K.
Published: October 2024

Regenerative medicine is an emerging branch of medicine holding tremendous power to cure in contrary to conventional treatment. Stem cells being at forefront of regenerative medicines holds unprecedented capability of self-renewal and cell differentiation, where this capability is the sole of the stem cell therapy. The cell therapy works by replacing the injured and collapsed cells with the regenerative ones in a chronic condition. But as there are always accompanying downsides with every benefit in this case it’s the ethical consideration, risk and cost associated to the usage and treatment. This review article aims to analyze the status of both stem cell therapy and research by outlining the regulatory landscape for developing, manufacturing and conducting of stem cell therapy in the countries namely US, EU, Japan and India in a comparative mode. The unethical and unproven stem cell tourism happening worldwide will also be highlighted in this review. In the realm of life-threatening medical procedures, addressing regulatory loopholes is a matter of utmost importance. The need for well-coordinated, robust, and meticulously enforced regulations cannot be overstated. These comprehensive regulatory frameworks play a pivotal role in ensuring that scientific advancements in this domain are conducted with the highest levels of safety and ethical integrity
FEATURES OF THE PROCESS OF YOUTH POLITICAL SOCIALIZATION IN RUSSIAN SOCIETY IN CONDITIONS OF DIGITIZATION
Authors:   Povolzhsky Institute of Management named after P.A. Stolypin, Branch of RANEPA, BRYANTSEV I.I. , Bryantseva O.V. ,   Saratov State Law Academy
Published: October 2024

The purpose of the article is to analyze current areas of interaction between society and the state in solving problems of spiritual and moral education of the younger generation, to form the continuity of generations based on the assimilation and reproduction of traditional values basic to society which are a necessary condition for cultural and civilizational identity. The role of the state in solving these problems is to formulate a policy adequate to emerging challenges through the creation of an institutional environment that creates favorable, non-antagonistic, conflict-free conditions for society for the implementation of public initiatives and the development of a system of public relations in the global digital communication space. The specifics of interaction between the state and civil society structures in the system of public relations and political socialization of youth in the implementation of national policy aimed at ensuring national interests are outlined. In conclusion the authors sum up that in order to solve these problems it is necessary to develop a model of interaction that would unite the efforts of the state, society and individuals. The following are identified as elements of this model at the level of public authorities and civil servants: the need to develop and improve competencies based on the use of the capabilities of the digital communication environment; increasing the level of responsibility of employees in their interaction with citizens; guiding the performance of their official duties by the principles of patriotism and service to society; building open, trusting relationships in the implementation of joint projects aimed at solving socially significant problems; eliminating any possibility of incorrect relations with citizens and the public which can provoke a negative formation of public opinion and reduce the effectiveness of the system of public relations formed by the authorities.
MEMORY POLITICS IN THE SYMBOLIC POLITICS OF POST-SOVIET STATES AND IN THE LEGITIMIZATION OF POWER: BASIC SCIENTIFIC THEORIES AND APPROACHES
Authors:   Central Russian Institute of Management, Branch of RANEPA, Ryazantsev A.A.
Published: October 2024

The formation of political regimes in the republics of the former USSR is helped by the implementation of an active symbolic policy, which contributes to the legitimation of power in the majority of states formed after 1991. The presented article reflects scientific theories and approaches to the phenomenology of symbolic politics considered in the interaction of the political power of new polities and social strata and population groups of these states. The relevance of the chosen topic of the article lies in the study of the algorithm for the implementation of symbolic politics in new conditions that influence the legitimation and strengthening of political power in new states. Field research: political institutions, processes and technologies. The purpose of the article is to present and justify the author’s definition and phenomenology of the symbolic politics of post-Soviet states in line with scientific theories and approaches to understanding the role of states and public policy. The subject of the study is the essential characteristics of symbolic politics in the processes of legitimation of political regimes in the republics of the former USSR. As a result of the research conducted by the author, on the basis of scientific theories and approaches to public policy, the essence of the symbolic policy pursued in the states of the post-Soviet space is substantiated. Problem statement: the constructed collective historical memory and political mythology in the post-Soviet space, implemented by state institutions and non-state actors, provides a solution to the following problems. In particular, the legitimation of political power, the success of the formation of civil identity and the construction of a political nation. The study of successful examples of symbolic policies of new states has a chance of practical application in the Russian Federation.
COGNITIVE MAPS OF INFORMATION FLOWS OF CONSOLIDATED AND DECONSOLIDATED DIRECTIONS IN RUSSIAN SOCIAL MEDIA (2023-2024)
Authors:   Financial University under the Government of the Russian Federation, DOMBROVSKAYA A.Yu. , BRODOVSKAYA E.V. ,   Financial University under the Government of the Russian Federation
Published: October 2024

The relevance of the stated topic is dictated by the increasing information and military confrontation between the Russian Federation and the West and the need in these conditions to monitor the level of social consolidation, which largely depends on the social and media support of the solidarity effect on Russian society. The purpose of the study is to identify the key characteristics of cognitive maps of information flows representing attitudes towards consolidation and deconsolidation of Russian society. The objectives of the analysis are to identify contexts, triggers, discourses, target audiences, actors, technologies for the formation of public attitudes, to determine the pool of actors and authors of consolidation and deconsolidation content of the Russian segment of social media. The characteristics of the consolidation flow include patterns of using collective security as a basis for solidarity, maintaining a value consensus, positive national-state identity, and maintaining sovereignty as a basic value. Signs of deconsolidation flows are the exploitation of social deprivation to undermine public trust in the authorities, devaluation of the importance of independence and state sovereignty, instructional, irrational, and manipulative influence on public opinion. In conclusion, as one of the results of the study, measures for information support of consolidation work in social media are presented.