bluuebunny/crossref_metadata_2025 huggingface dataset:
Jasmonate activates secondary cell wall biosynthesis through MYC2-MYB46 module
Authors: Han Kyung Hwan , Im Jong Hee , Son Seungmin , Kim Won-Chan , Kim Kihwan , Mitsuda Nobutaka , Ko Jae-Heung
Published: February 2023

The formation of secondary cell walls is tightly regulated
spatio-temporally by various developmental and environmental signals.
Successful fine-tuning of the trade-off between secondary cell wall
biosynthesis and stress responses requires better understanding of how
plant growth is regulated under environmental stress conditions.
However, current understanding of the interplay between environmental
signaling and secondary cell wall formation is limited. The
lipid-derived plant hormone jasmonate (JA) and its derivatives are
important signaling components involved in various physiological
processes including plant growth, development, and abiotic/biotic stress
response. Recent studies suggest that JA may be involved in secondary
cell wall formation. We tested this hypothesis using the transcription
factor MYB46, a master switch for secondary wall biosynthesis, and JA
treatments. Both the transcripts and protein levels of MYB46 were
significantly increased by the JA treatments, which also triggered the
upregulation of MYB46 downstream genes with increased secondary wall
formation. We then show that this JA-induced upregulation of MYB46
function was mediated by MYC2, a basic helix-loop-helix (bHLH)
domain–containing transcription factor, which plays a pivotal role in
the JA-mediated changes. We conclude that this MYC2-MYB46 module is a
key component of the plant response to JA signaling.
Biotechnology; an Evolving Dimension of Security
Authors: Yadav Pankaj , Bhujel Prabina
Published: February 2023

Biotechnology is the science of applied biological process that blends
natural science and engineering to comprehend and control biology at the
molecular level for a profound impact. It accomplishes gene
recombination, cloning of living things, and splicing of genes from the
DNA of one organism into the genome of unrelated species. It plays a
significant role in bio-agriculture, genomics, biochips, medicines,
robotic military, bioinformatics, the biotech industry, stem cell
research, fingerprinting, and bio-manufacturing which is essential for
improving national security. Modern biotechnology is a multidisciplinary
field and has proven a miracle for militaries from both; an offensive
and defensive standpoint. Biotechnology has both prospects and
constraints. Bio-weapons lead to disasters more dangerous than nuclear
accidents. The database freely available on the internet has the
potential for the development of a wide range of novel pathogens that
can attack the plant, animal, and human populations worldwide.
Biotechnology has created amazing possibilities and brought radical
changes for the military in bio-armory, bio-sensors, biocomputing,
bioengineered materials, biofuels, and biomimetics. This article
highlights aspects of biotechnology as an evolving dimension of
security, legal defense mechanisms, collaboration, and adherence of
different concerned authorities, and analyzes ways to counter different
threats of a bioweapon and boost national security. Nevertheless, it is
clear biotechnology will be as important to consumer economics in the
next century as physics and chemistry were in the last century.
Assessment of outcome of Trial of Labour after caesarean in a tertiary hospital based setting : Prospective Observational Study
Authors: Bhardwaj Mahak , Gainder Shalini , Chopra Seema , Bagga Rashmi
Published: February 2023

Objective: To determine the success rate of vaginal birth after
caesarean (VBAC) in Indian women, identify the factors that predict its
success, and assess the maternal and neonatal outcomes following a trial
of labour after caesarean (TOLAC). Design: Prospective observational
study Setting: Department of Obstetrics and Gynaecology, Post Graduate
Institute of Medical Education and Research, Chandigarh, India Sample:
124 women with previous LSCS who opted for TOLAC Methods: A prospective
observational study involving women with one previous lower segment
caesarean section (LSCS) who were admitted for TOLAC between January
2019 and June 2020. Main outcome measures and Results: During the study
period, 124 women with previous LSCS who opted for TOLAC were included,
of whom 68 (54.8%) had successful VBAC and 56 (45.2%) had failed
TOLAC. The induction of labour (IOL) rate in the study was 69.4%, and
30.6% of women had spontaneous onset of labor. VBAC rates were
significantly higher in women who went into labour spontaneously (84.2%
vs. 15.8%). Maternal complication rates were comparable, whereas the
neonatal complication rate was significantly higher in neonates born by
CS (51.7% vs. 30.8%), with a greater incidence of low birthweight
(LBW) and transient tachypnea in the newborn (TTNB). Conclusions: TOLAC
can be considered a safe option for women with a previous caesarean when
combined with vigilant and stringent labour monitoring, despite the use
of IOL agents. Funding : Not applicable.
A Novel Non-intrusive Load Monitoring Method Using Low Frequency Signal
Authors: Yuan Jie , Jin Ran , Wang Lidong
Published: February 2023

Non-intrusive load monitoring(NILM) can identify the appliance
categories, using time, work duration and the work states through data
collected from a smart meter. With NILM technique,people can conduct the
power supply and power consumption scientifically and reasonably so as
to partially or completely solve the problem of imbalance between power
supply and demand. The low-frequency non-invasive load state
identification algorithm can identify the load using low-frequency
signal without additional hardware facilities, so it has broad
development prospects. However, it is difficult to improve the accuracy
of low-frequency load identification because there is little information
available. In this paper, a low-frequency non-invasive load state
identification algorithm combining electrical switch state
classification LSTM algorithm and maximum likelihood probability
algorithm based on recursive reasoning is proposed. The load
identification is divided into two steps, which reduces the overall
difficulty and improves the accuracy of state identification. The
experimental results on Ampsd2 data set show that the proposed algorithm
can achieve better results than other NILM algorithms.
On Code Reuse from StackOverflow: An Exploratory Study on Jupyter Notebook
Authors: Tang Yutian , Yang Mingke , Zhou Yuming , Li Bixin
Published: February 2023

Jupyter Notebook is a popular tool among data analysts and scientists for working with data. It provides a way to combine code, documentation, and visualizations in a single, interactive environment, facilitating code reuse. While code reuse can improve programming efficiency, it can also decrease readability, security, and overall performance. We conduct a large-scale exploratory study of code reuse practices in the Jupyter Notebook development community on the Stack Overflow platform to understand the potential negative impacts of code reuse. Our findings identified 1,097,470 Jupyter Notebook clone pairs that reuse Stack Overflow code snippets, and the average code snippet has 7.91 code quality violations. Through our research, we gain insight into the reasons behind Jupyter Notebook developers’ decision to reuse code and the potential drawbacks of this practice.
Peptide ligands for the affinity purification of adeno-associated viruses from HEK 293 cell lysates
Authors: Menegatti Stefano , Chu Wenning , Shastry Shriarjun , Barbieri Eduardo , Prodromou Raphael , Greback-Clarke Paul , Smith Will , Moore Brandyn , Kilgore Ryan , Cummings Christopher , Pancorbo Jennifer , Gilleskie Gary , Daniele Michael A.
Published: February 2023

Adeno-associated viruses (AAVs) are the vector of choice for delivering
gene therapies that can cure inherited and acquired diseases. Clinical
research on various AAV serotypes significantly increased in recent
years alongside regulatory approvals of AAV-based therapies. The current
AAV purification platform hinges on the capture step, for which several
affinity resins are commercially available. These adsorbents rely on
protein ligands – typically camelid antibodies – that provide high
binding capacity and selectivity, but suffer from low biochemical
stability and high cost, and impose harsh elution conditions (pH
< 3) that can harm the transduction activity of recovered
AAVs. Addressing these challenges, this study introduces peptide ligands
that selectively capture AAVs and release them under mild conditions (pH
6.0). The peptide sequences were identified by screening a focused
library and modeled in silico against AAV serotypes 2 and 9 (AAV2
and AAV9) to select candidate ligands that target homologous sites at
the interface of the VP1-VP2 and VP2-VP3 virion proteins with mild
binding strength (K ~ 10
-10 M). Selected peptides were
conjugated to Toyopearl resin and evaluated via binding studies against
AAV2 and AAV9, demonstrating the ability to target both serotypes with
values of dynamic binding capacity (DBC
> 10 vp per mL of resin) and product
yields (~50-80%) on par with commercial adsorbents. The
peptide-based adsorbents were finally utilized to purify AAV2 from a HEK
293 cell lysate, affording high recovery (50-80%), 80-to-400-fold
reduction of host cell proteins (HCPs), and high transduction activity
(up to 80%) of the purified viruses.
A DCSRO Based Time Domain MAC Core
Authors: Musah Tawfiq , Du Kevin , Abdelaziz Ahmed
Published: February 2023

This article presents a time domain multiply-and-accumulate (MAC) engine
used for convolutional neural networks. Time domain is chosen for
efficiency as it allows for compact representation of multi-bit inputs
on a single wire. This reduces gate count and switching capacitance
(Cdyn) compared to traditional all-digital implementation. The inputs
are encoded by selecting a pulse of varying width depending on input
code. The multiplication operation and accumulation is implemented using
a digitally controlled switched-ring oscillator time-to-digital
converter functioning as a time accumulator. The digital control allows
for accumulation and quantization of two signals simultaneously, halving
the required time to quantize a certain value. The proposed MAC is
designed in a 28nm CMOS process and can achieve a simulated power
efficiency of 0.32pJ/b, which is 1.8X better than what can be achieved
by a single input gated ring oscillator (GRO) design.
Improvement of the quality of education, approaches, and methods for assessing the quality of educational services
Authors: Tarasova Mariya I. , Bronnikova Evgeniya M. , Kulyamina Olga S. , Vasileva Lidia A. , Ponyashova Anastasia S.
Published: February 2023

The article reveals the theoretical aspect of the formation of prerequisites for improving the quality of education, approaches, methods, and criteria for assessing the quality of educational services. In preparing the article were used Russian and foreign scientific publications, international ratings of educational organizations. The analysis of the assessment of the quality of educational services in foreign countries allowed systematically considering the process of reforming the educational sphere, considering the needs of society and the requirements of state standards, identify urgent methodological problems and formulate proposals that determine the practical significance of the study. The article highlights the patterns of the potential development of students, touches on the issues of assessing the quality of educational services through state accreditation, audit, statistical reporting, and standardization of the quality of educational services. The article reveals methods to evaluate the quality of educational services used in Russia and abroad.
Pinguisane-type sesquiterpenoids, unique secondary metabolites of liverworts: A review
Authors: Filipovic Sonja , Bijelic Ana , Bogdanovic Andrija , Radulovic Niko
Published: February 2023

This review summarizes the current knowledge on pinguisane-type
sesquiterpenoids, unique secondary metabolites of Hepaticae, their
isolation, structural elucidation, possible biosynthetic pathways, total
synthesis, and biological/pharmacological activities. Overall, 76 compounds
are presented, the majority of which are isolated from or detected in
liverwort material as secondary metabolites, while 4 compounds represent
artifacts of the isolation procedure. Pinguisane-type sesquiterpenes can be
used as chemotaxonomic markers for different taxonomic levels of liverworts,
as well as to delineate chemical as well as evolutionary relationships
within the Marchantiophyta phylum.
Kinetic–spectrophotometric approach to the ampicillin hydrolytic degradation applied for the histidine determination
Authors: Rasic-Misic Ivana , Tosic Snezana , Pecev-Marinkovic Emilija , Kostic Danijela , Arsic Biljana
Published: February 2023

The objective of this research was to develop a kinetic-spectrophotometric
method for the determination of microquantities of L-histidine in pure form
and dietary supplements. The method was based on the kinetics of ampicillin
degradation by Ni(II) ion as a catalyst in the presence of L-histidine in a
strongly alkaline medium. The rate of this reaction was monitored
spectrophotometrically by measuring the increase in absorbance at 265 nm as
a function of time. The same approach was used for the investigation of the
reaction rate in the absence of histidine. A differential variant of the
tangent method was used to process the kinetic data. Beer?s law was obeyed
in the interval of histidine concentration from 1.24 ?g/ml to 11.63 ?g/ml
with the relative standard deviation ranging from 8.1% to 0.7%. The
detection limit of 0.46 ?g/ml was estimated based on the 3S0 criterion. The
interference effects of some metal ions, anions, and other molecules on the
reaction rate were studied to assess method selectivity. Herein described
method was applied for the quantification of histidine in dietary
supplements. The point hypothesis test confirmed that there was no
significant difference between the proposed and the reference method.
Rosa canina L. fruit and jam made of it – natural food colors E160a and E160d content and antioxidant capacity
Authors: Miljkovic Vojkan , Nesic Milica , Mrmosanin Jelena , Gajic Ivana , Miladinovic Bojana , Stojanovic Dusica
Published: February 2023

Rosehip is one of the richest sources of vitamin C, and the jam made from it
tastes delicious. In this work, the content of food colors E160a (lycopene)
and E160d (?-carotene) was determined, as well as the antioxidant capacity
of these food products. By applying the UV-Vis spectrophotometric method and
using the Lambert-Beer law, a system of two linear equations with two
unknowns was set up, which was used to determine the concentrations for the
colors E160a and E160d. The content of lycopene and ?-carotene in dried
rosehip fruit and jam was 2.34 and 0.85, and 7.25 and 2.01 mg in 100 g of
fruit/jam, respectively. The antioxidant capacity of the samples was
determined by the DPPH test. The antioxidant capacity of fruit and rosehip
jam was 6.84 and 4.17 ?mol of Trolox/100 g of fresh sample. Thermal
processing affects the content of lycopene, ?-carotene, and antioxidant
capacity. The obtained results reveal beneficial effects of the everyday
consumption of dried rosehip fruit and jam.
Effects of perceived vs actual frequency of rewards on orthodontic patient attitudes and compliance
Authors: Yee Alan , Chu Wendy , Sinha Pramod , Mohajeri Amir , Hung Man , Kritz-Silverstein Donna
Published: February 2023

Objectives

To examine the longitudinal association of different reward schedules on patient compliance (as measured by oral hygiene assessments). The cross-sectional associations of actual vs perceived rewards frequency on patient attitudes were also examined.

Materials and Methods

138 patients undergoing treatment at a university orthodontic clinic were surveyed to collect information on perceived frequency of rewards, likelihood of making patient referrals, and attitudes toward reward programs and orthodontic treatment. Oral hygiene assessment from the most recent appointment and actual frequency of rewards were obtained from patient charts.

Results

Among participants, 44.9% were male, age ranged from 11 to 18 (mean = 14.9 ± 1.7) years; treatment time ranged from 9 to 56 (mean = 23.2 ± 9.8) months. Mean perceived frequency of rewards was 48% while actual frequency of rewards was 19.6%. There were no significant differences in attitudes by actual reward frequency (P > .10). However, those who perceived always receiving rewards were significantly more likely to have more positive opinions of reward programs (P = .004 and P = .024). Age- and treatment-time adjusted analyses showed that always receiving actual rewards was associated with odds of good oral hygiene 3.8 times (95% CI = 1.13, 13.09) higher than those never/rarely receiving actual rewards, but there was no association between perceived rewards and odds of good oral hygiene. Actual and perceived reward frequencies were significantly and positively correlated (r = 0.40, P < .001).

Conclusions

It is beneficial to give rewards to patients as often as possible to maximize compliance (as shown by hygiene ratings) and foster positive attitudes.
Metrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy
Authors: Zhou Yuxia , Liu Lu , Jin Bangming , Wu Yixuan , Xu Lifen , Chang Xuebing , Hu Laying , Wang Guifang , Huang Yali , Song Lingyu , Zhang Tian , Wang Yuanyuan , Xiao Ying , Zhang Fan , Shi Mingjun , Liu Lingling , Wang Tuanlao , Yan Rui , Guo Bing
Published: February 2023

Ectopic lipid accumulation in renal tubules is closely related to the pathogenesis of diabetic kidney disease (DKD) and mitochondrial dysfunction is thought to play a key role in lipid accumulation. Therefore, maintaining mitochondrial homeostasis holds considerable promise as therapeutic strategies for the treatment of DKD. Here we reported that Meteorin-like (Metrnl) gene product mediates lipid accumulation in the kidney and has therapeutic potential for DKD. We confirmed the reduced expression of Metrnl in renal tubules, which was inversely correlated with DKD pathological changes in patients and mouse models. Functionally, pharmacological administration of recombinant Metrnl (rMetrnl) or Metrnl overexpression could alleviate lipid accumulation and inhibit kidney failure. In vitro, rMetrnl or Metrnl overexpression attenuated palmitic acid-induced mitochondrial dysfunction and lipid accumulation in renal tubules accompanied by maintained mitochondrial homeostasis and enhanced lipid consumption. Conversely, shRNA-mediated Metrnl knockdown diminished the protective effect on the kidney. Mechanistically, these beneficial effects of Metrnl were mediated by the Sirt3-AMPK signaling axis to maintain mitochondrial homeostasis, and through Sirt3-uncoupling protein-1(UCP1) to promote thermogenesis, consequently alleviating lipid accumulation. In conclusion, our study demonstrated that Metrnl regulated lipid metabolism in the kidney by modulating mitochondrial function and serves as a stress-responsive regulator of kidney pathophysiology, which sheds light on novel strategies for treating DKD and associated kidney diseases. 
High speed coating for pure copper by multi-beam laser metal deposition method with high intensity blue diode lasers
Authors: Takazawa Yuma , Sato Yuji , Takenaka Keisuke , Yamashita Yorihiro , Kunimine Takahiro , Tsukamoto Masahiro
Published: February 2023

Copper is expected to have many applications due to its virus inactivation properties, but it has been difficult to produce a thin layer with high bonding strength. A multi-beam blue diode laser installed laser metal deposition (B-LMD) system was newly developed with a laser intensity of 4.7 × 105 W/cm2, which is improved about five times higher than that of conventional systems. Using this system, we demonstrated the high-speed formation of a pure copper layer on a stainless steel type 304 (SS304) circular tube. A pure copper powder and the blue diode lasers were simultaneously supplied to a SS304 circular tube, and the powder was melted and solidified to form a pure copper layer on it. As the result, the laser intensity was increased with increasing layer formation efficiency, and at the laser intensity of 4.7 × 105 W/cm2, the maximum value of layer formation efficiency was obtained at the peripheral speed of 400 mm/s. Moreover, it was revealed that the dilution length was decreased with increasing peripheral speed, the minimum value of 3 μm at the peripheral speed of 400 mm/s was obtained.
Evaluasi Pemasaran Jasa Pendidikan Tinggi Keguruan dan Ilmu Pendidikan Perguruan Tinggi
Authors: Butarbutar Vera Manondang Damaianty , Bambang Ismanto
Published: February 2023

Pandangan terhadap ketertinggalan pendidikan yang dihadapi Papua mendorong untuk meningkatkan kualitas pendidikan. Penelitian ini bertujuan untuk melakukan evaluasi terhadap pemasaran pendidikan tinggi pada Fakultas Keguruan dan Ilmu Pendidikan. Penelitian ini dilakukan dengan metode deskriptif analisis dan pendekatan kualitatif. Model evaluasi yang digunakan adalah Goal Oriented Evaluation Model oleh Tyler dengan pendekatan Marketing Mix (5P-Product, Price, Place, People dan Promotion) untuk membantu penjabaran pemasaran di tiap aspek pemasarannya. Pengambilan data dilakukan dengan cara Observasi, Wawancara dan Dokumentasi. Analisis dilakukan secara kualitatif tentang Marketing Mix yang menggunakan 5P (product, price, people, place, dan promotion). Hasil penelitian terkait evaluasi terhadap 5P menunjukkan bahwa perumusan tujuan umum, tujuan khusus, dan tujuan terkait perilaku konsumen untuk aspek product, place, dan promotion sudah cukup jelas, dan mudah untuk dipahami. Namun, evaluasi menemukan bahwa dalam pemasarannya belum ditemukan adanya penentuan terkait situasi dan teknik pengukuran yang akan digunakan untuk menentukan keberhasilan tujuan yang sudah dirumuskan. Dalam pemasaran Price (harga) dan People belum ditemukan rumusan tujuan umum, tujuan khusus, maupun tujuan terkait perilaku.
Family Tourist Characteristics in Parenting Health Education Model Approaches Bio Massage and CHSE Based at Kids Club Hotel Nusa Dua Bali
Authors: Ribek Nyoman , I Ketut Labir  , Ni Luh Ketut Suardani  , Wija Negara  , Ni Made Dewi Ayu Virgayanti
Published: February 2023

This research is motivated by the absence of a kids club hotel development module to reduce family tourists' worries about illness in children at tourist attractions, burdening families and parental burnouts and unfulfilled travel needs. The purpose of this research was to analyze the characteristics of family tourists, the level of anxiety, parental burnout, and the need for parenting health education, and to find a model design for parenting health education. The research method in phase 1 uses a quantitative descriptive research approach with a survey approach. The sampling strategy uses a purposive side technique with a sample size of 100 people during the survey and will be followed by the FGD method with 30 people. The results showed that the characteristics of family tourists were that most tourists were from foreign countries, especially Australia, enough worries, enough parental burnout, and health education parenting needs such as standards, achievement of quality and basic needs of children in health education parenting at kids club hotels were categorized as sufficient. It was concluded that foreign tourists need guidelines for the kids club model to reduce worries about falling ill at tourist attractions so that it becomes an attraction to increase the arrival of foreign family tourists.
The influence of the features of the design scheme and its input parameters on the amount of deformations of the soil mass
Authors:   L. N. Gumilyov Eurasian National University Astana, Zhussupbekov A. Z. , Ulitsky V. M. ,   Emperor Alexander I St. Petersburg State Transport University, Dyakonov I. P. ,   Saint Petersburg State University of Architecture and Civil Engineering, Ershova M. V. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: February 2023

This article provides a brief overview of the problems of determining the stress-strain state of the soil. In the course of the work, a generalized computational scheme of loading in St. Petersburg was constructed and analyzed using numerical soil models (Mohr-Coulomb, Hardening Soil).When analyzing the design scheme, there were used numerical calculation methods, based on the results of which there was determined the impact of the geometric dimensions of the scheme and the soil model on the soil settlement. As an example, there is considered the excavation of a deep pit in conditions of dense urban development with subsequent analysis of the trajectory of soil stresses. The results of this study can be used in the development of additional components to the existing methodology for determining the stress-strain state of the soil to improve the accuracy of calculations.
Improving the Working Conditions of the Personnel of the Pneumatic Forging Hammer according to Vibration Parameters
Authors:   Udmurt State University, Ivanov Yu.V. , Gabdrahmanov R.R. ,   Udmurt State University
Published: February 2023

Forging and stamping production is the basis of the procurement base of mechanical engineering. A variety of forging and pressing equipment ensures the production of most of the stampings and forgings used at the blank production stage. Working conditions in the forging shops are traditionally far from perfect. The main reasons for this are the number of unfavorable factors present in the forging shops, the main ones being noise and vibration, which most negatively affect the maintenance personnel. The article focuses its main attention on the evaluation of the vibrational activity of forging and pressing machines. It is indicated that vibration-isolating installations for stamping and forging hammers were developed. There are no such installations for pneumatic forging hammers. The results are given concerning the study on the design of a vibration-isolating installation for pneumatic forging hammers as a type of vibration-active equipment. To reduce the vertical vibrations of this equipment, multi-leaf springs are used, which efficiently reduce vibrations and have a long service life. Performance of the vibration isolating structure is ensured by installing a hammer on an intermediate frame supported by the springs installed in the foundation pit. The frame eliminates the rocking of the hammer and provides a uniform load on the spring. Parametric analysis of the vibration isolation unit showed that when the stiffness of the shock absorbers used is changed, the vibration activity of the machine can be reduced. A vibration-isolating installation for a forging pneumatic hammer, designed to improve the working conditions of personnel, was developed and successfully tested in production. Thanks to this installation, the vibration activity of the machine was significantly reduced and brought into line with sanitary standards, which improved the working conditions of the blacksmith and his assistant. Efficiency of vibration isolation is not changing in all modes of the hammer operation. The developed design is recommended for wide implementation in forging shops to improve the vibration characteristics of the hammer and to provide the possibility of placing such machines near vibration-sensitive objects.
Experimental and Analytical Studies of Critical Conditions for Flare Combustion of Gases and Vapors of Cryogenic Fuels
Authors:   FGBU VNIIPO EMERCOM of Russia, Bolodyan I.A. , Vogman L.P. ,   FGBU VNIIPO EMERCOM of Russia, Karpov V.L. ,   FGBU VNIIPO EMERCOM of Russia
Published: February 2023

The need to organize emissions of a large amount of gas arises in a number of technological operations related to the transportation, storage and processing of combustible gases, preparation and purging of containers, etc. The largest emissions occur during emergencies. For a correct assessment of the level of fire hazard and the choice of efficient ways to prevent fires, it is required to study in detail many defining parameters. First of all these are the limiting conditions for stabilization and extinguishing of diffusion flame of the torch. An analysis was made of the formation and stabilization conditions of a diffusion torch formed during the outflow of combustible gas from various gas discharge devices. On the basis of theoretical studies based on a single physical model, analytical expressions are derived. They describe the limiting conditions for the stabilization of turbulent diffusion torches in a wide range of changes in gas outflow conditions and parameters of the surrounding atmosphere. The proposed dependences allow to evaluate the complex effect of various factors (gas composition, gas discharge velocity and direction, size and shape of vents, wind speed, oxygen concentration in the surrounding space) on the parameters of turbulent diffusion torches. Within the framework of the study, the experimental regularities of stabilization and gas-dynamic extinguishing of turbulent diffusion torches are determined. These regularities make it possible to evaluate the influence of various factors (the degree of dilution of the combustible gas with an inert gas, the size and shape of the discharge hole, wind speed and oxygen concentration in the surrounding space) on the limiting conditions for stabilization of diffusion torches.
Machine Translation of Selected Ghazals of Hafiz from Persian into English
Authors: Ghassemiazghandi Mozhgan
Published: February 2023

Neural Machine Translation (NMT) is an end-to-end learning approach for automated translation with the potential to overcome many weaknesses in conventional phrase-based translation systems. However, there are still grey areas that need attention in the field of machine translation, mainly in the context of literary translation and poetic language. This research aims to identify the shortcomings of the NMT in addressing ambiguity and the semantic complexities of poetic expressions that are important in translating literature in a cross-cultural and multilingual context. Furthermore, while human translators struggle to retain naturalness and accuracy in translation, this research aims to identify to what extent machine translation could convey the message in translating literary-based texts from Persian into English. The corpus of this study consists of Forty ghazals from the Divan of Hafiz, which is translated by a computer-assisted translation software, memoQ and then compared to the authentic translation of Hafiz by Henry Wilberforce Clarke. This comparative descriptive study portrayed the challenges and issues related to Hafiz’s poems, which demonstrate that the literary touch is lost in MT products.
FACTORS OF STUNTING IN TODDLERS: A LITERATURE REVIEW
Authors: Halim Filiyanti , Ermiati Ermiati , Sari Eka Afrima
Published: February 2023

Stunting in toddlers is one of the health problems that has not been resolved globally, also in Indonesia. Stunting can be prevented by early detection based on the risk factors for the disease. The literature review aims to examine those articles and find out every risk factor for stunting in toddlers. This literature study used a scoping review method by searching through several search engines such as Google Scholar, ProQuest, PubMed, and EBSCO. After sorting the articles, there are 21 articles used in this literature study. The results of this literature study showed twenty-one risk factors for stunting in toddlers, such as exclusive breastfeeding and the initiation of early breastfeeding.  A history of low birth weight, immunization, the number of family members, insufficient nutritional needs (energy, iron, protein, calcium, and zinc), colostrum, breastfeeds (age of administration, type, and frequency). The practice of washing hands, mothers' occupation, mothers knowledge, low family income, history of infectious disease, sanitation and cleanliness of the environment, parents' height, especially mothers, lack vitamin C and vitamin D also as risk factors for stunting.  To conclude, stunting in toddlers was influenced by various factors which are child factors, parents, socio-economic, and environmental factors.  Therefore, it is essential to consider all the factors to develop stunting early detection tools for toddlers ang health education materials.
Acupressure Reducing Complaints Of Nausea And Vomiting Patient With Tuberculosis
Authors: Platini Hesti , Pebrianti Sandra , Kosim Kosim
Published: February 2023

Adverse effects of pulmonary tuberculosis treatment that often arise in the first month are nausea. This effect causes the occurrence of non-compliance with taking anti-tuberculosis drugs. For this reason patients with tuberculosis need non-pharmacological management such as acupressure. Acupressure is a mechanical or compressive manipulation based on one or more movements of certain meridians or points. This study aims to determine the effect of acupressure on nausea and vomiting in pulmonary tuberculosis patients due to the effects of pharmacology. The method was used quantitative design with a quasi-experimental design with pre-test and post-test with group control. The measuring instrument for nausea and vomiting was the Rhodes Index of Nausea Vomiting and Retching. The population was all pulmonary tuberculosis patients in category 1 treatment. The sample technique used is consecutive sampling. Sampling was consisted complaining nausea with or without vomiting. Data was analysis using t-test. The results was showed significant difference before and after the intervention to reduce nausea and vomiting (p = 0.000). Acupressure is a complementary therapy that can effectively reduce complaints of nausea and vomiting in pulmonary tuberculosis patients which is carried out at points P 6 and St 36 for 15 minutes. This research can be used as a recommendation for applying complementary acupressure therapy in providing nursing care to tuberculosis patients
Mental Health Children during Pandemic Covid 19: A Bibliometric Study
Authors: Sukaesih Nunung Siti , Pramajati Hikmat , Lindasari Sri Wulan , Lindayani Emi , Dolifah Dewi , Sopiah Popi
Published: February 2023

The coronavirus 2019 (Covid- 19) pandemic offers incredible challenges to child and adolescent health because the school closure and the impracticability of activities outside the house have been challenging for parents. When schools are closed, they lose an anchor in life, and their symptoms could relapse; these unstoppable circumstances, which are beyond average experience, are primary to stress, anxiety, and a feeling of helplessness in all. This research aimed at identifying, analysing, and examining children's mental health during pandemic articles published in several reputable international journals issued in the 2019-2020 timeframe, which was led using bibliometric studies. This research hires a bibliographic study using systematic and explicit mapping methods. The research was conducted using a 4-stages systematic mapping method: (1) searching for articles using the Publish or Perish application in the Scopus database, (2) classifying the articles for the bibliometric analysis, (3) checking and completing the metadata of those articles, and (4) conducting bibliometric analysis using VOSviewer application. The bibliometric analysis produced four findings, as follows: (1) the trend of mental health children’s publications 2019-2020; (2) the ten most contributive journals has published; (3) the ten most cited articles has produced 170 citations; (4) the five highest order of author keywords most widely used in mental health children’s articles were mental health, children, human, school, and covid- 19. Children's mental health can be concluded as the term of research is currently popular among researchers.
Psychological Impact of Unwanted Pregnancy on Adolescents: A Literature Review
Authors: M.Kep., Sp. Mat Ermiati , Nugraha Eko , Pratiwi Nindi , Lathifah Artanti , Nurrahmawati Devi , Karizma Tri , Turjanah Eka
Published: February 2023

The unwanted pregnancy in adolescents is increasing every year. The impact of unwanted pregnancy towards the adolescents can form as physical and psychological. The psychological impact which is not resolved can result in depression and even suicide. The purpose of this literature review is to determine the psychological impact on adolescents who experience the unwanted pregnancy.This literature review used narrative review related to the psychological impact of adverse events on adolescents. The databases used for this study are Google Scholar, Science Direct, Proquest, Pubmed, Researchgate, and Garuda Portal. The keywords used in Indonesian are, dampak psikologis” dan “kehamilan tidak diinginkan” dan “remaja”. The English keywords are “impact” and “unwanted pregnancy” OR “unintended pregnancy”, “teenager” OR “adolescent”. 32 articles were obtained according to the inclusion criteria were open access, full texts with publication years between 2010-2020 and 9 articles were selected for further review. The results showed the psychological impact of the unwanted pregnancy on adolescents are shame, fear, disappointment, anxiety, crying, guilt, irritability, being introverted, frustrated, angry, aggressive, panic, regret, stress and depression. Suggestion: The results of this literature review are expected to be a reference in further and in-depth research regarding the impact of unwanted pregnancy on adolescents so that the number of unwanted pregnancies in adolescents will no longer increase if they know the impact of unwanted pregnancies.
Description Fear of Missing Out (FoMO) in Undergraduate Students at Faculty of Nursing
Authors: Komala Kintan , Rafiyah Imas , Witdiawati Witdiawati
Published: February 2023

Social media makes it easy for internet users to communicate that is not limited by time and place. Excessive use of social media can have a negative impact, namely Fear of Missing Out (FoMO). FoMO on students will have an impact on increasing the duration of smartphone use while studying in class which can interfere with learning concentration and reduce students' academic achievement. This study aims to determine the description of Fear of Missing Out (FoMO) in undergraduate students of the Faculty of Nursing, Padjadjaran University. This study uses a quantitative descriptive design. The population of this study was nursing students of an undergraduate program with active status in the even semester of the 2020/2021 academic year at Padjadjaran University. The sampling technique used in this study was stratified random sampling with a value of e = 5% (0.05), a sample of 242 students was obtained. The instrument used in this study was the Fear of Missing Out scale (FoMOs). Data analysis in this study is univariate analysis using the mean and standard deviation. Based on the results of this study, it was found that most of the respondents experienced moderate level of FoMO (67.8%), then a small proportion were at low level of FoMO (16.9%) and high level of FoMO (15.3%). The conclusion of this study is that most respondents experience moderate level of FoMO, education and counseling are needed for students regarding Fear of Missing Out. Future researchers can conduct more in-depth research on the factors and impact of FoMO on nursing students.
Overview of Critical Reflective Work Behavior in Nursing Profession Students
Authors: FERNANDA NI PUTU MULIA , Susanti Raini Diah , Eriyani Theresia
Published: February 2023

Informal learning in the work/practice environment can be seen through critical reflective work behaviour, namely a series of activities to optimize individual and group practice. This study aims to describe critically reflective work behaviour (CRWB) and its dimensions, namely individual CRWB, CRWB in social interaction, openness to new findings and cross-checking information on internship nursing students of the Faculty of Nursing, Universitas Padjadjaran. This research design is descriptive quantitative with a modified critically reflective work behaviour questionnaire instrument. The instrument test is a content test through expert judgment, face validity on 23 respondents with good test results, construct test (r = 0.41), and reliability test (Cronbach's Alpha = 0.765). The study population was internship nursing students from the Faculty of Nursing, Padjadjaran University (N=208). A total sampling technique did sampling with a response rate of 74.5% (n=155). Ethics permit number 513/UN6.KEP/EC/2021 from the Research Ethics Commission of Padjadjaran University Bandung. The results showed that the nursing profession students of the Faculty of Nursing, Universitas Padjadjaran, tend to have high PKRK (56.1%). Social interaction is in the moderate category (69%). When viewed on each dimension, high results were also obtained on the individual CRWB dimension (77.4%), the openness dimension to new findings (56.8%), and the information cross-check dimension (72.9%). A high CRWB shows that students can adapt to changing circumstances and construct knowledge actively and personally. Suggestion: It pays attention to the peer evaluation method because it relates to the CRWB dimensions in social interactions, including sharing critical opinions, asking for input from others, challenging group thinking, and being open about one's mistakes.
Telehealth Blood Pressure Monitoring Models In Hypertensive Patients: A Scoping Review
Authors: Fathurrizki Ahmad Ihsan , Lestari Adinda Putri , Azizah Wafiq Nurul , Sari Eka Afrima
Published: February 2023

The main global cause of death in the world is non-communicable diseases (NCDs). One of NCD is hypertension. Increased hypertension during the Covid-19 pandemic is associated with risk factors for lifestyle changes, social restrictions, lack of physical activity, and stress. Therefore, a remote blood pressure control system is needed to monitor the patient’s health status. The purpose of writing this literature review is to provide an overview of health care practices with remote monitoring of blood pressure of hypertension patients based on online management with telemonitoring. the method used is scoping review with the inclusion criteria of articles were published from 2017 – 2021, used the research designs of Randomized Control Trial and Study Experimental, and were published in English and Indonesian. Articles selections were using PRISMA Flow Diagram 2009 and selection for eligibility were using. The Joanna Briggs Institute Critical Appraisal. Four articles were included in the study and 1037 articles were excluded from the study. It was found that telehealth blood pressure monitoring carried out in hypertensive patients was home and online blood pressure management, TASMINH (Telemonitoring and Self-Management in the Control of Hypertension), and scale-up blood pressure. Telemonitoring was found to be significant in reducing and monitoring patients with home care-based hypertension Self-Monitoring Blood Pressure (SMBP) at home using a digital sphygmomanometer accompanied by direct monitoring of doctors and nurses via the internet can be a solution for monitoring blood pressure during a pandemic.
Optimal Dosing of Enoxaparin in Critically Ill Patients with Venous Thromboembolism
Authors: Abdulla Aliya , Williams Caitlin M. , Branan Trisha N. , Smith Susan E.
Published: February 2023

Background: Evidence suggests that goal anti-Xa levels are achieved in only 33% of critically ill patients receiving standard prophylactic enoxaparin dosing. There has been limited focus on the potential suboptimal anticoagulation effect on medical intensive care unit (MICU) patients receiving therapeutic enoxaparin dosing for venous thromboembolism (VTE).
Methods: MICU patients receiving enoxaparin 1 mg/kg twice daily or 1.5 mg/kg daily for VTE treatment in a 350-bed community teaching hospital between 2013 and 2019 with at least one peak anti-Xa level measured were included. The primary outcome was the proportion who achieved therapeutic anti-Xa levels with standard dosing. Secondary outcomes included types of dose-adjustments required and the proportion requiring subsequent dose-adjustments. Descriptive statistics were presented for all outcomes.
Results: Fifty-three patients were evaluated, including those receiving either twice-daily or once-daily standard therapeutic dosing. Optimal anti-Xa levels at first measurement were recorded after the initiation of enoxaparin in 26.4% (n=14) patients. Dose adjustments were required in 70.7% (n=29) of patients receiving twice-daily dosing and in 83.3% (n=10) receiving once-daily dosing (P=0.97) to appropriately increase or decrease the enoxaparin dose. By the third anti-Xa level measurement, 3 patients remained outside of the therapeutic range.
Conclusions: Standard therapeutic enoxaparin dosing did not result in optimal anti-Xa levels for a majority of MICU patients regardless of dosing regimen used or patient specific factors. Future studies should identify patient factors associated with the requirement for higher or lower enoxaparin dosing.
Organization of EMC enhancement measures for modern ships
Authors:   Krylov State Research Centre, St. Petersburg, Russia, Gorodetsky B.N. , Vishnevsky А.М. ,   Krylov State Research Centre, St. Petersburg, Russia, Gorshkov A.I. ,   Krylov State Research Centre, St. Petersburg, Russia
Published: February 2023

Object and purpose of research. This paper discusses organization of the measures intended to enhance EMC and electromagnetic robustness of ships in accordance with regulations. The purpose is to obtain an optimal procedure for practical implementation of KSRC-developed methodology intended to ensure electromagnetic compatibility of equipment aboard marine objects and their robustness against electromagnetic attacks. Subject matter and methods. The methodology mentioned above is centered around scientific and engineering support of the object at all stages of its life cycle. It requires participation of numerous organizations and enterprises in charge of specifications development, equipment design, testing (acceptance, etc.), as well as operation of the object. Therefore, development of an optimal scenario for participation of all these organizations and enterprises at various life cycle stages of marine object becomes a relevant task. Main results. This paper discusses the whole participation scenario for all organizations and enterprises over the entire life cycle of marine objects, including the most sophisticated ones, i.e. ships, in terms of practical implementation for KSRCdeveloped methodology of EMC and electromagnetic robustness enhancement. It demonstrates that this task requires special test facilities, with enumeration of their respective key capabilities. It also describes the peculiarities of industrial degaussing/deperming/EMC test center established at KSRC in accordance with the requirements set out in this paper. Conclusion. Practical implementation of EMC and electromagnetic robustness enhancement methodology for marine objects is centered around optimal combinations of protective tools and measures (taken by both equipment manufacturers and ship designers coordinated by a dedicated agency in charge of scientific and engineering support) and requires optimal work organization, as well as optimal interaction between all stakeholders over the entire life cycle of marine object. Practical implementation scenario for this methodology relies on industrial test facilities and makes it possible to achieve EMC and electromagnetic robustness of various objects, including ships, in an optimal manner.