bluuebunny/crossref_metadata_2025 huggingface dataset:
The Collaborative Effort and Efficiency of Inquiry-Based Learning
Authors: Miraz Mahadi Hasan , Saleheen Ferdoush , Ashif Abu Sadat Muhammad , Hossain Mohammad Amzad , Hasan Mohammad Tariq , Hwang Ha Jin , Kabir Anuwarul
Published: May 2023

This study investigates the effect on the teacher's performance of collaborative effort and efficiency of inquiry-based learning. It also determines the impact of the mediating role of student performance. The research framework was constructed based on the unified technology acceptance and use of technology theory. A quantitative analysis was done with surveys to collect primary data from the teacher and lecturers of Malaysia. The researcher used a Likert scale of 7 to evaluate elements of the building. This study focuses on the top 10 public university students in Malaysia. The universities are University Malaya (UM), University Kembangan Malaysia, University Putra Malaysia (UPM), University Since Malaysia (USM), University Technology Malaysia (UTM), Universiti Utara Malaysia (UUM), International Islamic University Malaysia (IIUM), University Technology Mara (UiTM), University Malaysia Perlis (UniMap), and University Tun Hossain (UTHM). Finally, researchers selected the total number of students, 368,881, which is the population of this study. Using systematic random sampling with an interval, researchers sent students an electronic link to respond to a Google Doc questionnaire. This is a unique study in the field of teacher performance that used a diverse and necessary variable known as teaching pedagogy. Therefore, it uniquely integrates leading pedagogy variables into teacher performance. The result of this study helps to meet the education qualification requirement (EQR), and the newly acquired knowledge from this study may help spur the development of the education sector. In addition, it may provide an extensive understanding of making government policies for educational institutions.
Biofluid Characterisation Using Pin on Disc Experiment from Plant Based Oil
Authors: Mahat Mohamad Mazwan , Mohd Rohazid Izatul Aina Afiqah , Kazwa Farah Nabillah , Kamaldin Nurul Nadiah
Published: May 2023

This study focuses on the performance and mechanical characteristics response of pure Canola oil and Canola oil with existence of Hyaluronic Acid. Numerous studies show that plant-based substances are infrequently used in synthetic synovial fluid. The sort of bio-fluid that derives from plant-based oil and can function as a synthetic synovial fluid is the focus of this work. Three samples of a bio-fluid made of Canola oil with three different concentrations of Hyaluronic Acid (HA) are 0 ml, 5 ml, and 10ml, respectively. The 500 mm x 500 mm x 4 mm Polylactic Acid (PLA) biomaterial disc was chosen in the pin on disc wear and friction test rig experiment in conjunction with a canola-based oil tested lubricant to simulate the mechanical principles on the knee. To obtain accurate findings for the wear rate and friction coefficient, the samples will be put through a tribology test. The experiment was conducted to measure the tribology of the stainless pin to observe the effect of coefficient of friction and wear rate on the pin. The reliable outcome may open up new avenues for future research on synthetic synovial fluid. On the other hand, this study is beneficial to medical technology for future treatment of any diseases related to synovial fluid and allows the manufacturer to improve understanding in the optimization of these lubricants in ensuring a long-term application in the human body.
Finite Element Analysis of Low-Velocity Impact Carbon Fiber-Reinforced Polymer (CFRP) Composite Laminate Emphasizing on Meshing Technique
Authors: Meon Mohd Suhairil
Published: May 2023

This paper presents the performance of the three-dimensional progressive damage model using Puck failure criteria gradual degradation law to predict the structural responses, as well as the onset and propagation of failure due to different meshing techniques. The proposed damage model is performed using Abaqus explicit analysis. Three meshing strategies are analyzed using a solid element finite element model based on low-velocity impact loading. The structural responses are compared with experimental data taken from literature to measure the performance of such damage model. The results revealed that the models adopted here respond well to experimental data and demonstrate acceptable results in predicting the inter- and intra-laminar damage of the composite laminate.
Phytochemical Compounds and Antioxidants Analysis of Clinacanthus nutans Leaf and Stem Extracts
Authors: Hasyim Saiyidah Nafisah , Sidik Norrizah Jaafar , Chay Tay Chia , Rodzali Nur Nadirah , Abdullah Siti Nur Azmu’i , Muhammad Noor Amira
Published: May 2023

Clinacanthus
nutans consists with multiple medicinal properties. The plant is also known to be a source of biologically active compounds, particularly those with an antioxidant capacity. The phytochemical studies of C. nutans plant extract was mostly reported from its leaf part. Thus, the objectives of this study are to assess the phytochemical constituents and antioxidant activity of C. nutans leaf and stem. Methanol was used as solvent for the green extraction. Next, phytochemical screening, Fourier transform infrared (FTIR) analysis, total phenolic (TPC) and flavonoids contents (TFC), quercetin flavonoid compound analysis and in vitro antioxidant activity were performed on C. nutans leaf and stem. In comparison to stem extract, the leaf extract showed a more favorable appearance of metabolites. In FTIR analysis, both sample extracts revealed the presence of hydroxyl and carbonyl functional groups, which are important in antioxidant action. The TPC (228.06 mg GAE/g DW) and TFC (29.76 mg QE/g DW) values were higher in the leaf extract than the stem extract. Quercetin quantification in HPLC analysis revealed that the leaf extract (21.33 g/g) contained more quercetin than the stem extract (18.88 g/g). Between the extracts, leaf providing more antioxidant values of DPPH (15.50%) and FRAP (15.68 gFeSO4/g) than stem. The greatest association was identified between TFC and FRAP reducing activity (r = 0.977, p<0.05) indicating that the flavonoid present in the extract contributed to C. nutans' antioxidant capacity.
CFD Performance Analysis of Journal Bearing Using Coconut Oil as Lubricant
Authors: bin Ariffin Ammar , Sainan Khairul Imran , Latip Syazuan Bin Abdul
Published: May 2023

Lubrication is one of the important factors for a journal bearing to function well. Therefore, the use of bio-lubricants such as coconut oil and vegetable oil are highly recommended for their high level of biodegradability to reduce the risk of environmental pollution. Vegetable oil like coconut oil has a great lubricating quality including low friction coefficient and improved oxidation stability which is very suitable to be used as a lubricant. The performance assessment of journal bearings utilizing coconut oil as a bio-lubricant and varying angular velocity and eccentricity ratio will be the main emphasis of this study. The behavior of the journal bearing with coconut oil as the lubricant will be examined using the Computational Fluid Dynamics (CFD) program, ANSYS Fluent. Using ANSYS Fluent, the pressure distribution of pure coconut oil is analytically studied. To evaluate the efficacy of each lubricant with a varied value of angular velocity utilized by the journal in journal bearings, average viscosity, viscosity index, and produced maximum pressure can be discovered under the lubrication of the journal bearing. Using the values of angular velocity with the same value of dynamic viscosity and density as properties for the coconut oil were used to run the simulation for the journal bearing. The result obtained from the simulation for eccentricity ratio of 0.2 with an angular velocity of 5000rpm is 205926.1 meanwhile the result for eccentricity ratio of 0.8 with same angular velocity value is 9661441. Each result signifies those different value of angular velocity with different value of eccentricity ratio that effects the bearing design itself occurs different result.
Extraction Yield of Palm Oil and Carotenoids Value from Microwave-Sterilized Oil Palm Mesocarp
Authors: Kamaruddin Amirah Hanani , Zamanhuri Norashikin Ahmad , Raslan Rafeqah
Published: May 2023

Steam batch sterilization is favorably utilized by conventional palm oil mills in Malaysia. However, there are some disadvantages to using steam batch sterilization, including the fact that it takes a long time to complete the sterilizing process, and a huge amount of wastewater is released as palm oil mill effluent (POME). Besides, extraction by fruit press expeller requires a large number of nuts or seeds to produce a high yield, which is relatively expensive. Therefore, this research aimed to investigate the capability of microwave sterilization and the Soxhlet extraction (solvent extraction) process as an alternative to the conventional method. The impact of various microwave power levels of 400, 600, and 800 W and water ratios of 0, 50, and 100 mL on oil yield and carotenoids value of microwave-sterilized oil palm mesocarp are also investigated. Microwave sterilization and Soxhlet extraction have been employed as a replacement for the conventional method of extracting a higher yield of palm oil mesocarp in order to fill the gap by the previous research, which applied two methods: microwave sterilization (power level) and extraction. Then, carotenoid value analysis with a UV spectrophotometer is utilized to examine the outcomes in order to demonstrate the efficacy of the method. As a result, a high oil yield and carotenoid value are produced, which is 59.31% at 800W with the absence of water (0 mL) and a carotenoid value of 757 ppm at 400W (0 mL), respectively. Meanwhile, other carotenoid values at different microwave power levels and water ratios are still within the acceptable range as per the commercial crude palm oil standard.
Surface Chemistry Interaction of Graphene Oxide/Eggshell Adsorbent towards Fluoride Removal
Authors: Mohamad Nor Norhusna , Azmir Mohamad Ikmal Mohamad , Amri Nurulhuda
Published: May 2023

Fluoride removal is crucial in water sources because its existence is very harmful towards human and environment. With this concern, graphene oxide (GO) has been selected as an adsorbent due to its adsorptive characteristics. GO was modified with eggshell (GO/ES), a natural based of calcium precursor. The modification of the GO/ES adsorbent was done via ultra-sonification. The effects of each synthesis parameter toward fluoride removal were investigated and related to surface functional groups found in the modified GO/ES adsorbent. From the analysis, eggshell has been successfully decorated over GO structure, where GO-calcium bond was observed in the FTIR spectra. The interaction between GO and ES showed the increment of hydroxyl (O-H) and carboxyl (C-O) functional groups as increasing in ES amount. This resulted in increasing of fluoride removal, as high as 54.30 mg/g adsorption capacity. The effects of GO/ES ration, sonication temperature and synthesis time in tailoring the modified GO/ES adsorbent were also significant in the arrangement of these functional groups towards fluoride removal. Based on the results obtained, it can be concluded that modified GO/ES adsorbent, from natural calcium source is comparable with chemical based calcium source, where the same functional groups were observed from FTIR spectra.
Removal of Iron and Manganese in Groundwater Using Alum and Potassium Permanganate
Authors: Nizam Khairul Hafiz Shahrul , Zainuddin Nur Syahiza
Published: May 2023

Groundwater has become one of the natural sources of water nowadays. Naturally, groundwater contains dissolving materials such as soils, rocks, and minerals, which later release constituents, including iron (Fe2+) and manganese (Mn). However, raw groundwater has been found to consist of a high concentration of such minerals, which exceed the Groundwater Quality Standard published by the Department of Environment Malaysia. Initially, the concentration of Fe2+ and Mn exceeding the limit mentioned in the standard; 1.0 and 0.2 mg/L, respectively, might affect the quality of the groundwater. Hence, such condition of water needs to be treated before it can be distributed to the user. This study presents the combination usage of alum and potassium permanganate (KMnO4) in removing Fe2+ and Mn in the groundwater. The jar test was the main mechanism used in identifying the best optimum medium dosages (alum and KMnO4) as well as the best contact time for both mediums to efficiently remove Fe2+ and Mn in groundwater. In this study, water samples were taken from Chicha Water Treatment Plant in Kelantan. It can be said that both alum and KMnO4 managed to remove Fe2+ and Mn up to 35% and 45%, respectively when using alum dosage of 12 mg/L and KMnO4 dosage of 1.5mg/L with a contact time of 40 minutes. In addition, both mediums also managed to remove other parameters such as colour, turbidity, cations, and pH.
Geographical, environmental, and biotic constraints define the spatial distribution of Diaphanosoma species (Cladocera)
Authors: Nascimento Jaielle R. , Braghin Louizi S.M. , Cabral Camila R. , Caliman Adriano , Simões Nadson R.
Published: May 2023

Species distribution is a combination of ecological, historical, stochastic, and evolutionary mechanisms, and is a process that has been severely impacted by anthropogenic activities. Freshwater zooplankton is adequate to assess that combination because it groups cosmopolitan and endemic species. We hypothesized that the spatial distribution of Diaphanosoma species is defined by a complex interaction between factors such as spatial limitation, limitation of environmental conditions, and ecological conditions. We georeferenced the occurrence of Diaphanosoma in Brazil to study the potential distribution of the species, preference of ecoregions, environmental features associated with Diaphanosoma, and their co-occurring patterns. Five species of Diaphanosoma are widely distributed in Brazil. D. spinulosum and D. birgei were widely distributed while D. fluviatile and D. polyspina had a more restricted distribution. The occurrences of Diaphanosoma species were shown to have an association with factors such as the total concentrations of nitrogen and phosphorus, pH and, temperature, except in the case of the D. brevireme. Our results show that geographic, environmental, and biotic filters can drive the spatial distribution of species of the genus Diaphanosoma. Therefore, the distribution and spatial occurrence of these species depend on dispersal capacity and spatial restrictions, suitability of the abiotic environment, and ecological interactions.
Complicanze emorragiche nell'assistenza infermieristica al paziente adulto in circolazione extracorporea: revisione della letteratura
Authors: Binda Filippo , Lazzarini Alessandro , Accardi Roberto
Published: May 2023

I pazienti sottoposti alla circolazione extracorporea (ECMO) necessitano di elevati dosaggi di anticoagulante per il buon funzionamento del circuito e ciò li espone ad un alto rischio emorragico. Le sedi più comuni di sanguinamento sono i siti di inserzione delle cannule, la cute e le mucose. Meno frequenti, ma potenzialmente fatali sono invece i sanguinamenti maggiori (polmonari, gastrointestinali, retroperitoneali e del sistema nervoso centrale).
COVID-19, è già tempo di fare un bilancio?
Authors: Giusti Gian Domenico
Published: May 2023

Questi ultimi due anni hanno profondamente ridisegnato e ridefinito la nostra professione, la pandemia COVID-19 ci ha messo di fronte alle difficoltà  del Servizio Sanitario Nazionale nel far fronte alle continue ondate a cui le professioni sanitarie, con gli infermieri in testa, hanno cercato di fronteggiare. Nonostante le grandi difficoltà  incontrate, oggi siamo consapevoli di avere armi (dispositivi di protezione individuale per proteggerci, vaccini per ridurre gli effetti della malattia aiutano a difenderci in questa guerra.
Scheda RCS per il riascolto delle chiamate di soccorso: studio di validazione
Authors: Zardo Caterina , Bortoli Nicola , Badon Pierluigi , Buchini Sara
Published: May 2023

Il Triage telefonico nelle richieste di soccorso è un momento critico e complesso e risulta fondamentale avere uno strumento valido, applicabile, efficace ed efficiente per il riascolto delle chiamate. Dalla scarsa presenza di letteratura si evince come la valutazione e il riascolto delle chiamate di soccorso sia un momento spesso trascurato. Questo studio si prefigge l'obiettivo di costruire e validare un nuovo strumento di analisi delle chiamate di soccorso.
Protocollo di ricerca per la validazione della versione italiana della Behavioral Pain Scale nei pazienti ricoverati in terapia intensiva pediatrica, sedati, intubati e ventilati meccanicamente
Authors: Sulla Francesco , Guasconi Massimo , Crudeli Irene , Giovannone Diletta , Giuffredi Sara , Zardo Caterina , Sarli Leopoldo , Artioli Giovanna , Scelsi Silvia
Published: May 2023

Introduzione: La gestione e la rilevazione del dolore nelle Unità  di Terapia Intensiva Pediatrica (UTIP) rimane tutt'oggi una delle sfide più difficili affrontate dagli operatori sanitari. La valutazione del dolore nel bambino è complessa e lo è ancora di più nell'ambitodelle UTIP. E' necessario l'utilizzo di strumenti adatti alla misurazione del dolore in UTIP e dalla letteratura si evince come il gold standard sia la COMFORT-Behavior (COMFORT-B) scale, strumento però non sempre utilizzato correttamente dai professionisti.Lo scopo del protocollo di studio è quello di validare la Behavioral Pain Scale (BPS) nell'ambito delle UTIP, valutandola nella rilevazione del dolore nei pazienti pediatrici intubati, sedati e ventilati meccanicamente.Materiali e metodi: Protocollo di studio di validazione della coerenza interna, affidabilità  inter-rater, validità  concorrente tra BPS e COMFORT-B e NRS e validità discriminante. Validità di facciata e di costrutto della BPS sono risultate adeguate in uno studio precedente. Il protocollo è stato approvato dal Comitato Etico Area Vasta Emilia Nord e autorizzato dall'Azienda Ospedaliera Universitaria di Parma e dall'Istituto Gaslini di Genova.Risultati attesi: Si ipotizza che possa essere dimostrata la validità della BPS per la misurazione del dolore in UTIP.Conclusioni: La BPS potrebbe diventare un strumento efficace e di facile utilizzo per gli infermieri nella rilevazione del dolore in bambini sedati ed intubati e ventilati meccanicamente, migliorandone così anche la gestione.Parole Chiave: Behavioral Pain Scale, Dolore, Paziente Pediatrico, Terapia Intensiva Pediatrica.
Il processo educativo in fase riabilitativa nell'assistito cardiochirurgico. Revisione narrativa di letteratura
Authors: Acqualagna Rachele , Mazzariol Elisa , Feltrin Catia , Bernardi Paola
Published: May 2023

Introduzione: Le patologie cardiovascolari costituiscono uno dei più importanti problemi di salute pubblica, rientrando tra le principali cause di morbosità, invalidità e mortalità. In particolare, l'intervento cardiochirurgico ha un forte impatto dal punto di vista psico-emotivo e nell'approccio della persona alle attività quotidiane. Si rivela dunque necessario elaborare un percorso che coinvolga attivamente l'assistito e che miri soddisfare i suoi bisogni per garantirne un rientro a domicilio coerente con le sue aspettative e le sue potenzialità. Lo scopo dell'elaborato è¨ individuare quali siano le migliori strategie infermieristiche atte a riconoscere e soddisfare i bisogni educativi dellâ€™assistitocardiochirurgico in fase riabilitativa e descrivere quali sono gli aspetti da considerare prioritari nellâ€™approccio educativo della persona.Materiali e metodi: Ãˆ stata condotta una revisione narrativa della letteratura da Marzo ad Agosto 2020, consultando la banca dati PubMed e CINAHL. Sono stati inclusi nella revisione 23 articoli.Risultati: Sono state individuate tre tematiche principali: le strategie infermieristiche utili a riconoscere i bisogni di natura educativa, tra cui lâ€™intervista ed i questionari self-report; le strategie infermieristiche volte a soddisfare i suddetti bisogni, coinvolgendo anche il caregiver; gli aspetti da tenere in considerazione nellâ€™approccio educativo dellâ€™assistito, tra cui si annoverano lâ€™etÃ  ed il genere.Discussione: I risultati ottenuti pongono lâ€™accento su come la fase riabilitativa e lâ€™educazione rivolta allâ€™infermiere debba prevedere lâ€™utilizzo anche di piÃ¹ strategie di identificazione del bisogno educativo, il coinvolgimento attivo di un caregiver ma soprattutto la stesura di un paino assistenziale che possa essere aderente alle aspettative della persona e condiviso dai team infermieristici nei vari setting.Conclusioni: La letteratura reperita ha permesso di rispondere ai quesiti di ricerca che hanno guidato la stesura dell'elaborato ed ha evidenziato come un continuum dell'assistenza nei diversi setting di cura agevoli la ripresa della quotidianità del soggetto.Parole Chiave: bisogni educativi, cardiochirurgia, caregivers, attività  di vita quotidiana.
Il profilo di posto dell'infermiere della Medicina d'Urgenza dell'Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino
Authors: Lanzarone Salvatore , Albano Rosina , Cerminara Vittoria , Gavetti Dario , Nanescu Eveline , Servidio Francesca , Todisco Andrea , Paleologo Mario
Published: May 2023

Il Profilo di Posto (PdP) è uno strumento formalizzato a carattere definitorio e manageriale che, attraverso l'esplicitazione delle attività professionali (AP), definisce uno standard di competenza precisando le responsabilità ed aspettative di ciascun ruolo. Il processo di costruzione risponde alle logiche di un'organizzazione per processo e consente di esercitare la riflessione sulla cultura organizzativa e l'empowerment. Nella Medicina d'Urgenza (MECAU) della AOU Città della Salute e della Scienza di Torino, considerato il percorso di riorganizzazione avviato e l'elevato turn-over degli Infermieri, si è reso necessario costruire uno strumento che descrivesse e favorisse lo sviluppo delle competenze professionali. L'obiettivo di questo lavoro è  la costruzione del PdP dell'Infermiere MECAU del PO S. Giovanni Battista - Molinette di Torino.
Studio prospettico comparativo tra due metodi di Triage Pre Ospedaliero del Trauma Maggiore
Authors: Ranzato Katya , Bagnato Clara , Giarracca Antonio Giarracca , Restelli Patrizia , Saronni Simone , Gadda Giorgio , Chiara Osvaldo , Cimbanassi Stefania
Published: May 2023

Il trauma maggiore nei paesi occidentali è un problema rilevante in quanto costituisce la principale causa di morte e disabilità  nella popolazione più giovane. Per garantire il miglior livello di assistenza in termini di efficacia e di efficienza del Sistema Integrato di Assistenza al Trauma l'appropriatezza e l'accuratezza dei criteri di triage sono fondamentali.
Controllo delle emorragie esterne post-traumatiche: analisi descrittiva tra infermieri di emergenza-urgenza toscani sulla campagna Stop the Bleed
Authors: Cini Silvia , Caietti Lorenzo , Ramacciani Isemann Christian , Garofalo Cinzia , Maggi Roberto , Righi Lorenzo
Published: May 2023

Introduzione: le emorragie esterne, pur rappresentando una causa di morte prevenibile, sono responsabili nel mondo di oltre 5 milioni di decessi all’anno. Le conoscenze sulle metodiche di primo intervento restano però scarse tra la popolazione e l’American College of Surgeons ha proposto la campagna Stop the Bleed (STB), con l’obiettivo di educare professionisti e cittadini sulle tecniche di controllo delle emorragie. In Italia solo in tempi recenti si è vista l’integrazione tra militari, civili e personale sanitario per diffondere le tecniche di base per il controllo delle emorragie. Per indagare le conoscenze dei professionisti ed evidenziare possibili aree di miglioramento, pertanto, è stato proposto questo studio.
Materiali e metodi: è stata predisposta una survey descrittiva per gli infermieri di emergenza-urgenza dell’Azienda USL Toscana sud est, con un questionario autocostruito composto da 16 domande a risposta chiusa, sulla campagna STB.
Risultati: la maggior parte del campione ha riferito di conoscere il protocollo STB ma un quinto del campione non ha mai sentito parlare dell’arresto delle emorragie in emergenza/urgenza durante il proprio percorso di studi; la maggior parte degli intervistati infatti è venuto in contatto con il protocollo STB solo in corsi di formazione continua o post-base. Circa un terzo degli infermieri ha avuto modo di utilizzare il protocollo STB, specialmente attraverso il Combat tourniquet. I partecipanti hanno ritenuto importante la predisposizione e la messa a disposizione di kit per il controllo delle emorragie esterne e la necessità di formare con il protocollo STB tutti gli operatori, anche laici, che operano nel territorio nell’ambito dell’emergenza-urgenza.
Discussione e conclusioni: nei paesi anglosassoni si sono sviluppati programmi di formazione estesi STB già in età scolastica, anche con modalità educative a distanza e utilizzando manichini più realistici. Appaiono opportuni, pertanto, una diffusione della campagna STB già nei corsi universitari di base, nelle scuole superiori e nei gruppi più a rischio di emorragie esterne, una capillare messa a disposizione di kit salvavita e la predisposizione di un adeguato cruscotto di monitoraggio.
Diagnostic Value of the Optic Nerve Sheath in the Diagnosis of Increased Intracranial Pressure in Traumatic Brain Patients
Authors: Ziaei Maryam , Moodi Soudabeh , Pourafzali Seyed Mehdi , Abdolrazaghnejad Ali
Published: May 2023

Background:

Increased intracranial pressure (ICP) is a modifiable secondary injury that is associated with poor outcomes in patients with traumatic brain injuries (TBIs). Therefore, the present study was conducted with the aim of determining the ICP of TBI patients by measuring the thickness of the optic nerve sheath diameter (ONSD).

Materials and Methods:

The present cross-sectional study was conducted on 220 patients with severe TBI that referred to Khatam-al-Anbya Hospital in Zahedan in 2021. The measurement of ONSD was performed by ultrasonography.

Results:

The results of this study revealed that 22.7% of TBI patients had high ICP. The mean of right and left ONSD in patients with normal ICP was 3.85 ± 0.83 and 3.85 ± 0.82 mm, respectively, and was significantly lower than that of patients with abnormal ICP (high ICP) with the mean of 3.85 ± 0.82 and 6.12 ± 0.84 mm, respectively (P value <.001). In addition, the right ONSD with the cutoff point of 5.13 mm, the sensitivity of 84%, and the specificity of 95.29% and the left ONSD with the cutoff point of 5.24 mm, the sensitivity of 90%, and the specificity of 95.88% had a significant diagnostic value in the diagnosis of high ICP (P value <.05).

Conclusion:

The findings of the present study indicated that the measurement of ONSD is a cost-effective and minimally invasive procedure with a higher accuracy in diagnosing high ICP in TBI patients.
A Comparison of Oral Dydrogesterone with Vaginal Progesterone for Luteal-Phase Support in In Vitro Fertilization: A Randomized Controlled Trial
Authors: Naghshineh Elham , Ghasemi Tehrani Hatav , Sharifian Fatemeh , Haghighat Somayeh
Published: May 2023

Background:

The quality of the luteal phase is the most important issue affecting pregnancy outcomes in assisted reproductive technology (ART). Luteal-phase support with the administration of gonadotropin-releasing hormone (GnRH) agonist or progesterone improves the likelihood of pregnancy in ART. Due to disagreements regarding the best pharmaceutical form of progesterone for success of in vitro fertilization (IVF) in ART methods, the present study aimed to compare the clinical efficacy of oral dydrogesterone with vaginal progesterone on the outcome of pregnancy in IVF.

Materials and Methods:

This unblinded randomized clinical trial was conducted at the Shahid Beheshti Hospital, Obstetrics and Gynecology Centre in Isfahan, Iran, between june 2021 and September 2021. In total, 126 couples were included in the study. All patients underwent controlled ovarian stimulation and IVF. Patients were randomly divided into two groups (n = 63 per group). After embryo transfer, group I was treated with Cyclogest 400 mg twice daily, and group II was treated with oral Duphaston 10 mg twice daily.

Results:

No significant differences were observed between the two groups in terms of the mean endometrial thickness (P = 0.613), the mean number of transferred embryos (P = 0.100), and the number of implanted embryos (P = 0.338). Additionally, no statistically significant differences in the pregnancy rate were detected between the two groups (P = 0.875).

Conclusions:

The evidence from this study indicates that Duphaston is as effective as Cyclogest for luteal-phase support.
Identifying the Factors Affecting the Incidence of Congenital Heart Disease Using Support Vector Machine and Particle Swarm Optimization
Authors: Dehghan Bahar , Sabri Mohammad Reza , Ahmadi Alireza , Ghaderian Mehdi , Mahdavi Chehreh , Ramezani Nejad Davood , Sattari Mohammad
Published: May 2023

Background:

Congenital malformations are defined as “any defect in the structure of a person that exists from birth”. Among them, congenital heart malformations have the highest prevalence in the world. This study focuses on the development of a predictive model for congenital heart disease in Isfahan using support vector machine (SVM) and particle swarm intelligence.

Materials and Methods:

It consists of four parts: data collection, preprocessing, identify target features, and technique. The proposed technique is a combination of the SVM method and particle swarm optimization (PSO).

Results:

The data set includes 1389 patients and 399 features. The best performance in terms of accuracy, with 81.57%, is related to the PSO-SVM technique and the worst performance, with 78.62%, is related to the random forest technique. Congenital extra cardiac anomalies are considered as the most important factor with averages of 0.655.

Conclusion:

Congenital extra cardiac anomalies are considered as the most important factor. Detecting more important feature affecting congenital heart disease allows physicians to treat the variable risk factors associated with congenital heart disease progression. The use of a machine learning approach provides the ability to predict the presence of congenital heart disease with high accuracy and sensitivity.
Cytological Diagnosis of Pilomatrixoma and its Diagnostic Pitfalls
Authors: Khan Sabina , Abeer Inara , Husain Musharraf , Jetley Sujata
Published: May 2023

Background:

Pilomatrixoma (PMX) is a relatively uncommon benign cutaneous neoplasm arising from skin adnexa. It presents as a subcutaneous asymptomatic nodule mostly in the head and neck region and is frequently misdiagnosed by the clinicians. Although easily diagnosed on histopathology, the cytologic features of PMX are less distinctive, depending on the stage and evolution of disease and may mimic other benign or even malignant lesions.

Aim:

To study the cyto-morphological features of this uncommon neoplasm and identify its potential diagnostic pitfalls on fine needle aspiration cytology (FNAC).

Material and Methods:

Archival records of histopathologically diagnosed Pilomatrixoma were analyzed during study period of 2.5 years. Clinical diagnosis, preoperative FNA characteristics, and histopathological details were studied in each case. Cytologic pitfalls resulting in misdiagnosis of PMX cases on FNAC were evaluated in discordant cases.

Results:

The series showed male preponderance, with head and neck being the commonest site. Out of 21 histopathologically proven cases of PMX, cytological correlation was available in 18 cases. A correct cytologic diagnosis of PMX/adnexal tumor was rendered in 13 cases. Erroneous diagnosis was given in 5 cases mainly because of the predominance of one component over the other or non-representative-aspirated material.

Conclusion:

The present study highlights the importance of careful screening of FNAC smears keeping in mind the variability in the relevant cytologic features of PMX and creates awareness about the lesions that can mimic Pilomatrixoma resulting in diagnostic dilemma.
Positive Rate of Malignant Cells in Endometrial Cytology Samples of Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer Patients: A Systematic Review and Meta-Analysis
Authors: Wang Tiantian , Bin Yadi , Zhao Lanbo , Li Qiling
Published: May 2023

To estimate the feasibility of diagnosing ovarian cancer, fallopian tube cancer, and primary peritoneal cancer through endometrial cytology, we performed a systematic review and meta-analysis to calculate the pooled positive rate of malignant cells in endometrial cytology samples. We queried PubMed, EMBASE, Medline, and Cochrane Central Register of Controlled Trails from inception to November 12, 2020 for studies estimating positive rates of malignant cells in endometrial cytology samples from patients with ovarian cancer, fallopian tube cancer, and primary peritoneal cancer. The positive rates of the included studies were calculated as pooled positive rate through meta-analyses of proportion. Subgroup analysis based on different sampling methods was conducted. Seven retrospective studies involving 975 patients were included. Pooled positive rate of malignant cells in endometrial cytology specimens of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer patients was 23% (95% CI: 16% - 34%). Statistical heterogeneity between the included studies was considerable (I
2 = 89%, P < 0.01). The pooled positive rates of the group of brushes and the group of aspiration smears were 13% (95% CI: 10% - 17%, I
2 = 0, P = 0.45) and 33% (95% CI: 25% - 42%, I
2 = 80%, P < 0.01), respectively. Although endometrial cytology is not an ideal diagnostic tool for ovarian cancer, fallopian tube cancer, and primary peritoneal cancer, it is a convenient, painless, and easy-to-implement adjunct to other tools. Sampling method is one of the factors that affect the detection rate.
How to choose between high-flow nasal cannula, continuous positive airway pressure, and bilevel positive airway pressure in children with acute respiratory illness
Authors: Narayanan Karthik R , Ashwath Ram R N , Sundaram Manu
Published: May 2023

In pediatric patients with acute respiratory illnesses, the widespread availability of heated humidified high-flow nasal cannula (HHHFNC) devices, ease of use, and increased compliance have increased their use in conditions such as pneumonia, acute respiratory failure, asthma, and acute respiratory distress syndrome. Due to the patient comfort and ease of use of HHHFNC, there are widely used. Similarly, the use of NIV is increasing due to the availability of better interfaces and non-invasive ventilators (NIV) for use in infants The conundrum has been regarding the generation of positive end-expiratory pressure in these open circuits of the HHHFNC devices versus the pressures delivered by the closed circuits in the NIV devices. This article reviewed the latest literature based on the clinical conditions and the rationale for selecting respiratory support in common acute respiratory illnesses.
Flexible bronchoscopy in pediatric intensive care unit
Authors: Chugh Krishan , Talwar Neetu , Kori Manish , Mohite Kaustubh , Mohite Mahesh
Published: May 2023

Flexible bronchoscopy (FB) is a very rewarding procedure in the evaluation and management of appropriately selected children with respiratory issues in pediatric intensive care unit (PICU). An understanding of the alterations in respiratory physiology (airway resistance, compliance, and air exchange) during FB is absolutely essential for the safety of the child. To reduce discomfort and other side effects of FB it is necessary to optimize the condition of the child including sedation, analgesia, paralysis, ventilator settings, and cardiovascular status. With advancements in technology and instrumentation many interventional procedures can be performed safely and effectively using access to the airway through the endotracheal tube, tracheostomy tube, or Laryngeal Mask Airway (LMA). Close monitoring during and after FB minimizes complications.
Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases Ratio: A Biomarker of Bone Resorption in Geriatric Osteoporosis?
Authors: Bektan Kanat Bahar , Ulugerger Avci Gulru , Bayramlar Osman Faruk , Unal Damla , Sonmez Ozge , Bolayirli Ibrahim Murat , Doventas Alper , Erdincler Deniz Suna , Yavuzer Hakan
Published: May 2023

Background: Matrix metalloproteinases (MMPs) play an important role in bone resorption and are regulated by tissue inhibitors of metalloproteinases (TIMPs). We investigated the use of MMP2/TIMP2 and MMP9/TIMP1 ratios as biomarkers of bone resorption in geriatric osteoporosis and evaluated the relationship between osteoporosis and geriatric syndromes.Methods: This analytical cross-sectional study involved 87 patients (41 with osteoporosis) treated at the geriatric outpatient clinic of a university hospital. The demographic characteristics, comprehensive geriatric assessment scores, laboratory findings, and bone mineral density of the patients were recorded. Serum MMP9, TIMP1, MMP2, and TIMP2 levels were analyzed by enzyme-linked immunosorbent assay (ELISA).Results: We enrolled 41 and 46 patients with and without osteoporosis, respectively. The groups showed no significant differences in MMP2/TIMP2 and MMP9/TIMP1 ratios (p=0.569 and p=0125, respectively). While the basic activities of daily life (BADL) scores in the osteoporosis group were higher than those in the group without osteoporosis, the instrumental activities of daily life (IADL) scores were significantly lower (p=0.001 and p=0.007, respectively). No significant differences were observed in Mini-Nutritional Assessment, Mini-Mental State Examination, and Geriatric Depression Scale scores (p=0.598, p=0.898, and p=0.287, respectively). Conclusion: This is the first study to examine the relationship between osteoporosis and several geriatric syndromes, as well as the relationship between osteoporosis and serum MMP, TIMP values, and MMP/TIMP ratios in geriatric patients. Our results showed that osteoporosis causes dependency in both BADLs and IADLs, and that the MMP2/TIMP2 and MMP9/TIMP1 ratios provided no additional benefit in demonstrating bone resorption in geriatric osteoporosis.
Comparison between the Compressive Strength of Binary and Ternary Alkaline-activated Pozzolanic Concrete
Authors: Adeshokan M. O. , Arum C.
Published: May 2023

This research compared the compressive strength of binary and ternary alkaline-activated pozzolanic concrete. Rice husk ash (RHA) and Metakaolin (MK) combined partially with Ordinary Portland Cement (OPC) each are the binary concrete while the combination of rice husk ash and metakaolin (RHA/MK) combined partially with OPC is the ternary concrete. The OPC was replaced at 15% each with RHA, MK and RHA/MK in ratios 0.33 (X), 0.5 (Y) and 1.0 (Z) of sodium silicate (NS) to sodium hydroxide (NH) as activator. A mix design ratio of 1:2:4 and water-cement ratio of 0.65 with alkaline liquid to pozzolan of 0.30 was used in the process of the study. Physical properties of the constituent materials as well chemical analysis of pozzolans were determined. Slump and compacting factor tests were done on the freshly mixed concrete to determine their workability while compression test was performed on the hardened concrete cube samples of side 150mm to obtain the compressive strength. Curing was done for 7 and 28 days inside water tank. The result of the compression test showed that the compressive strength of the ternary concrete continuously increased as the sodium silicate to sodium hydroxide ratio increased. At the maturity age of 28days, the values of the compressive strength were 14.2 MPa, 17.5 MPa and 20.3 MPa for sodium silicate (NS) to sodium hydroxide (NH) ratios of 0.33, 0.5 and 1.0 respectively. These values are higher than the compressive strength for the binary concrete of RHA and MK taken separately for the same NS to NH ratios which at 28days curing age were 10.9 MPa, 14.8 MPa, 16.2 MPa for RHA and 14.0 MPa, 15.3 MPa, 18.2 MPa for MK. The result of the research can be used in the construction industry for normal concrete work as well as serve for effective waste disposal of agricultural waste products such as RHA and MK to reduce environmental pollution.
Advancements in Layered Double Hydroxide-Based Chemotherapeutic Nanosystems for Cancer Treatment
Authors: Omonmhenle S. I. , Ifijen I. H.
Published: May 2023

Globally, Cancer therapy is still a major issue. With the latest developments in nanotechnology, layered double hydroxide (LDH)-based nanosystems are receiving special attention due to their pH dependent biodegradability, superior biocompatibility, easy surface modification, anion exchange capacity and high chemical stability, giving rise to great potential for cancer therapy. By intercalating inorganic, organic, or bio molecules into their lamellar lattice, new hybrid materials with dual or multi-functional features, including anticancer capabilities, can be developed from layered double hydroxide (LDH). Despite the fact that outstanding research has been published, few review papers address these essential and promising discoveries to stimulate the ongoing development of LDH-based nanosystems in the field of cancer therapy. This paper therefore study focuses on the most recent advancements in LDH-based chemotherapeutic nanosystems for cancer treatment. The information utilized in this review was gathered from studies that have previously been published and were retrieved from several Journal outlets. These reports dealt with the usage of layered doubled hydroxide-based chemotherapeutic nanosystems for the treatment of cancer. The research demonstrates that layered double hydroxides may be utilized to develop single or composite nanosystems that distribute therapeutic components precisely without causing cumulative damage for the field of nanomedicine.
Design and Implementation of Biometric-Based Student Information Retrieval System Using Finger Prints Recognition
Authors: Omorogiuwa O. , Nwelih E. , Aweh O.
Published: May 2023

This study designed and implements a biometric-based student information retrieval system using finger print recognition. The findings showed that the existing manual system is prone to lots of errors such difficulties in accessing records, wrong data entry, difficulties in data manipulation, identity management and difficulties in updating students’ records. Structured system analysis and design methodology was adopted for this research. The design and implementation of the developed application software showed that computerized student information retrieval system using biometrics greatly enhanced the documentation, manipulation and retrieval of student information in a more accurate, fast and secured manner.
Response of 2-Hydroxymethyl Methacrylate Polymer Gel Dosimeter with Maltose Additive for Radiation within Diagnostic X-Ray Energies
Authors: Alhassan M. , Abdulrahman A. , Mustafa I. S.
Published: May 2023

The use of polymer gel dosimeters (PGD) in x-ray radiography has not yet been confirmed. However, if it could be applied, it could help to improve patient dosimetry, dose optimization, and quality assurance through its three-dimensional (3D) image display. This research aimed to evaluate the response of a 2-hydroxymethyl methacrylate (HEMA) polymer gel dosimeter at lower energies for possible use in diagnostic x-ray radiography and to determine the effect of maltose concentrations on the sensitivity. The dosimeter was made under normoxic conditions using Gelatin, HEMA, N, N’- Methylene – bis – acrylamide (BIS), Ascorbic Acid, deionized water, and maltose of various concentrations (10 – 50 mM). The PGDs were then irradiated using a conventional x-ray machine with exposure settings ranging from 10-200 mA, 40-100 kV, and s = 1 s. Afterward, the irradiated dosimeters were scanned using UV-spectroscopy. The result showed that the dosimeters responded to low-energy x-rays, and the effect of the maltose concentration within the tested range was not linear with the sensitivity. We concluded that the HEMA polymer gel dosimeter could be used for clinical x-ray dosimetry, but further research on the effect of maltose concentrations on the sensitivity is needed.
Effects of Aqueous Leaf Extract of Amaranthus tricolor On the Liver of the Adult Wistar Rat
Authors: Ehi-Omosun M. B. , Omoko O. G.
Published: May 2023

The aim of this study was to investigate the effects of aqueous leaf extract of Amaranthus tricolor on the liver of adult Wistar rats. 24 adult Wistar rats weighing between 250g and 280g were randomly assigned into 4 groups; (A-D) comprising of 6 rats per group. Group A rats were placed on rat food and water only. Group B rats received 100mg/kg body weight / day (BWT/D) of Amaranthus tricolor leaf extract. Group C rats received 300mg/kg BWT/D of Amaranthus tricolor leaf extract. Group D rats received 600mg/kg BWT/D of Amaranthus tricolor leaf extract. The dosages were given for 56 consecutive days via orogastric method. At the end of the 56th day, the animals were sacrificed under chloroform anaesthesia and the liver was harvested and processed for histological examination. The histological sections of the liver of the control group (Group A) showed normal histoarchitecture of hepatocytes radiating from the central vein with intervening sinusoids. There were no observable histological variations in the liver histoarchitecture of the rats treated with 100 mg/kg body weight (Group B), 300 mg/kg body weight (Group C) and 600 mg/kg body weight (Group D) of Amaranthus tricolor leaf extract. It was therefore concluded that Amaranthus tricolor leaf extract has no histomorphologic effects on the liver tissue of Wistar rats.
The Office of Deacon in the Reformed Church in Zimbabwe: A historical perspective.
Authors: Baloyi Rev. Dr. Ezekiel
Published: May 2023

A deacon is generally considered to be a member of the diaconate. This relates to an office in most Christian churches that is associated with some type of service offered, but the latter varies among denominations. The word deacon emanates from the Greek word diákonos which means a servant, minister, or envoy. The office of deacon was initiated in the selection of seven men by the apostles of Jesus, among whom was Stephen the proto-deacon. Their role was to assist with charitable works in the early church as it has been recorded in Acts chapter 6. This article deals with the office of the deacon and investigates it in the Reformed Church in Zimbabwe from a historical perspective. There are four offices of Church government in the
Reformed/Presbyterian system. These are the office of the minister of the Word, Professors of Theological School, elder and the deacon. The study holds that the office of the deacon plays an important role in the administration of finances in the Reformed Church in Zimbabwe. The aim of this study is to relate and re-evaluate the history of the office of the deacon from the establishment of the Reformed Church in Zimbabwe to date. The research contributes to the ongoing gathering and production of historical data of the history of the Reformed Church in Zimbabwe.