bluuebunny/crossref_metadata_2025 huggingface dataset:
Data Supplement from miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Authors: Gong Chang , Nie Yan , Qu Shaohua , Liao Jian-You , Cui Xiuying , Yao Herui , Zeng Yunjie , Su Fengxi , Song Erwei , Liu Qiang
Published: March 2023

Supplementary Figure S5. Smad 7 and PTEN are targets of miR-21 in PTs.
Data Supplement from miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Authors: Gong Chang , Nie Yan , Qu Shaohua , Liao Jian-You , Cui Xiuying , Yao Herui , Zeng Yunjie , Su Fengxi , Song Erwei , Liu Qiang
Published: March 2023

Legend for Supplementary Figures S1-S6.
Supplementary Figures 1 - 11 and Table 1 from Selective Inhibition of Parallel DNA Damage Response Pathways Optimizes Radiosensitization of Glioblastoma Stem-like Cells
Authors: Ahmed Shafiq U. , Carruthers Ross , Gilmour Lesley , Yildirim Salih , Watts Colin , Chalmers Anthony J.
Published: March 2023

Supplementary Table 1. Analysis of clonogenics survival curves from Figure 1C and 1D. Supplementary Figure S1. Generation of orthotopic tumours from R10 and R15 GSCs. Supplementary Figure S2. GSCs are more resistant to IR induced cell death than paired bulk populations. Supplementary Figure S3. Cell cycle profile and proliferation rates of GSC and bulk population. Supplementary Figure S4. Enhanced activation of CHK1 in GSCs. Supplementary Figure S5. Absence of G1 cell cycle checkpoint in irradiated GBM cell lines. Supplementary Figure S6. Analysis of G2/M cell cycle checkpoint. Supplementary Figure S7. Rapid activation of G2/M cell cycle checkpoint in E2 CD133+ cells. Supplementary Figure S8. Treatment of G7 GSCs with the CHK1 inhibitor SCH 900776 (SCH). Supplementary Figure S9. Radiosensitisation of E2 and G7 cell lines with the CHK1 inhibitor CHIR 124 (CHIR). Supplementary Figure S10. Enhanced DNA repair attenuates radiosensitisation of E2 GSCs to CHK1 inhibitor (SCH). Supplementary Figure S11. Increase in gamma-H2AX foci in GSCs compared to bulk population following combined ATR and PARP inhibition.
Supplementary Figure S4 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Authors: Faria Claudia C. , Golbourn Brian J. , Dubuc Adrian M. , Remke Marc , Diaz Roberto J. , Agnihotri Sameer , Luck Amanda , Sabha Nesrin , Olsen Samantha , Wu Xiaochong , Garzia Livia , Ramaswamy Vijay , Mack Stephen C. , Wang Xin , Leadley Michael , Reynaud Denis , Ermini Leonardo , Post Martin , Northcott Paul A. , Pfister Stefan M. , Croul Sidney E. , Kool Marcel , Korshunov Andrey , Smith Christian A. , Taylor Michael D. , Rutka James T.
Published: March 2023

Supplementary Figure S4. Prognostic impact of p-cMET status in SHH medulloblastomas
Supplementary Tables S1-S2 from CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus
Authors: Koh Siang-Boon , Courtin Aurélie , Boyce Richard J. , Boyle Robert G. , Richards Frances M. , Jodrell Duncan I.
Published: March 2023

Supplementary Tables S1-S2. Kinase specificity of S1181 (S1); Percentages of S-phase cells (S2).
Supplementary Figures S1-S5 from CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus
Authors: Koh Siang-Boon , Courtin Aurélie , Boyce Richard J. , Boyle Robert G. , Richards Frances M. , Jodrell Duncan I.
Published: March 2023

Supplementary Figures S1-S5. Effective synergy at sub-GI50 concentrations (S1); Mitotic entry at synergistic concentrations (S2); Cell fate upon gemcitabine and CHK1 inhibition (S3); Replication stress upon gemcitabine and CHK1 inhibition (S4); Mitotic aberration upon gemcitabine and CHK1 inhibition (S5).
supplementary figure 6 from Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia
Authors: Kim Jin-A , Shim Jae-Seung , Lee Ga-Young , Yim Hyeon Woo , Kim Tae-Min , Kim Myungshin , Leem Sun-Hee , Lee Jong-Wook , Min Chang-Ki , Oh Il-Hoan
Published: March 2023

supplementary figure 6: differences in all types of stromal cell components in BMs among AML patients with different clinical courses.
Supplementary Figure 1 from STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Authors: Lau Jasmine , Ilkhanizadeh Shirin , Wang Susan , Miroshnikova Yekaterina A. , Salvatierra Nicolas A. , Wong Robyn A. , Schmidt Christin , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: March 2023

Figure S1: Expression of mesenchymal genes, Pdpn and Chi3l1, in proneural and mesenchymal murine glioma models.
Supplementary Figure S3 from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: March 2023

Supplementary Figure S3. EMT following miR-135b/210 transfection.
Supplementary Figure S1 from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: March 2023

Supplementary Figure S1. mRNA expression profiles in resected metastases and matched primary tumors and normal tissues.
Supplementary Table 1 from An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer
Authors: Su Xiaoping , Wang Huaming , Ge Wei , Yang Mingjin , Hou Jin , Chen Taoyong , Li Nan , Cao Xuetao
Published: March 2023

Supplementary Table 1. Relative miRIP isolation of miRNAs predicted by TargetScan in HepG2 and PC-3 cells.
Supplementary Tables S1-S2 from Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors
Authors: Amin Amit Dipak , Rajan Soumya S. , Liang Winnie S. , Pongtornpipat Praechompoo , Groysman Matthew J. , Tapia Edgar O. , Peters Tara L. , Cuyugan Lori , Adkins Jonathan , Rimsza Lisa M. , Lussier Yves A. , Puvvada Soham D. , Schatz Jonathan H.
Published: March 2023

Supplementary Tables S1-S2. Relative IC50's of ALK+ and ALK- ALCL cell lines to the ALK tyrosine kinase inhibitors crizotinib and ceritinib (S1); ALK Kinase-Domain Sequencing Results (S2).
Supplementary References from Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors
Authors: Amin Amit Dipak , Rajan Soumya S. , Liang Winnie S. , Pongtornpipat Praechompoo , Groysman Matthew J. , Tapia Edgar O. , Peters Tara L. , Cuyugan Lori , Adkins Jonathan , Rimsza Lisa M. , Lussier Yves A. , Puvvada Soham D. , Schatz Jonathan H.
Published: March 2023

Supplementary References
Supplementary Figures S1-S5 from Evidence Suggesting That Discontinuous Dosing of ALK Kinase Inhibitors May Prolong Control of ALK+ Tumors
Authors: Amin Amit Dipak , Rajan Soumya S. , Liang Winnie S. , Pongtornpipat Praechompoo , Groysman Matthew J. , Tapia Edgar O. , Peters Tara L. , Cuyugan Lori , Adkins Jonathan , Rimsza Lisa M. , Lussier Yves A. , Puvvada Soham D. , Schatz Jonathan H.
Published: March 2023

Supplementary Figures S1-S5. Timelines for acquired resistance and resensitization (S1); Assessment of copy number changes in additional subclones (S2); RS lines behave like original parent cells with return of ALK expression to baseline (S3); Reselection of resensitized cells again selects for up-regulation of NPM-ALK and the resistant-dependent phenotype (S4); Assessing whether an up-front intermittent dosing regimen prolongs tumor control in vivo (S5).
Supplementary Figure S5 from α-Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration
Authors: Boggs Amanda E. , Vitolo Michele I. , Whipple Rebecca A. , Charpentier Monica S. , Goloubeva Olga G. , Ioffe Olga B. , Tuttle Kimberly C. , Slovic Jana , Lu Yiling , Mills Gordon B. , Martin Stuart S.
Published: March 2023

Supplementary Figure S5. High acetylation is linked to the basal-like subtype and reduced progression-free and overall survival in patients.
Supplementary Figure S2 from α-Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration
Authors: Boggs Amanda E. , Vitolo Michele I. , Whipple Rebecca A. , Charpentier Monica S. , Goloubeva Olga G. , Ioffe Olga B. , Tuttle Kimberly C. , Slovic Jana , Lu Yiling , Mills Gordon B. , Martin Stuart S.
Published: March 2023

Supplementary Figure S2. K40R α-tubulin does not affect proliferation in MDA-MB-231 or BT-549 cells but decreases McTN frequency under transient transfection conditions.
Supplemental Figure S5 from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Figure S5. Bioluminescence imaging microscopy.
Supplementary Table and Figure Legends from Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis
Authors: Oei Arlene L. , van Leeuwen Caspar M. , ten Cate Rosemarie , Rodermond Hans M. , Buist Marrije R. , Stalpers Lukas J.A. , Crezee Johannes , Kok H. Petra , Medema Jan Paul , Franken Nicolaas A.P.
Published: March 2023

Legends for Supplementary Tables SI-SIII and Supplementary Figures S1-S4.
Supplementary information from A Recurrent Activating PLCG1 Mutation in Cardiac Angiosarcomas Increases Apoptosis Resistance and Invasiveness of Endothelial Cells
Authors: Kunze Kristin , Spieker Tilmann , Gamerdinger Ulrike , Nau Kerstin , Berger Johannes , Dreyer Thomas , Sindermann Jürgen R. , Hoffmeier Andreas , Gattenlöhner Stefan , Bräuninger Andreas
Published: March 2023

Supplementary information. Supplementary Table S1. Antibodies used in the study. Supplementary Table S2. Primer sequences for Sanger sequencing and site-directed mutagenesis. Supplementary Table S3. SNP array analysis of 8 primary cardiac angiosarcomas. Supplementary Table S4. Mutations detected by tNGS of six primary cardiac angiosarcomas. Supplementary Table S5. Replacement and nonsense mutations detected by tNGS of six primary cardiac angiosarcomas. Supplementary Table S6. The PLCγ1-R707Q mutation increases migration and invasiveness of HUVECs. Supplementary Figure S1. Transfection efficiency with an EGFP encoding control plasmid. Supplementary Figure S2. Cell cycle distribution in HUVECs transfected with PLCγ1-R707Q, PLCγ1-WT and a control.
Supplementary Table S5 from Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
Authors: Eberlein Catherine A. , Stetson Daniel , Markovets Aleksandra A. , Al-Kadhimi Katherine J. , Lai Zhongwu , Fisher Paul R. , Meador Catherine B. , Spitzler Paula , Ichihara Eiki , Ross Sarah J. , Ahdesmaki Miika J. , Ahmed Ambar , Ratcliffe Laura E. , O'Brien Elizabeth L. Christey , Barnes Claire H. , Brown Henry , Smith Paul D. , Dry Jonathan R. , Beran Garry , Thress Kenneth S. , Dougherty Brian , Pao William , Cross Darren A.E.
Published: March 2023

Supplementary Table S5. RPPA analysis of phosphorylated and total protein levels in PC9 and NCI-H1975 AZD9291 resistant populations compared to respective parental cells.
Supplementary Figure S1 from Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis
Authors: Oei Arlene L. , van Leeuwen Caspar M. , ten Cate Rosemarie , Rodermond Hans M. , Buist Marrije R. , Stalpers Lukas J.A. , Crezee Johannes , Kok H. Petra , Medema Jan Paul , Franken Nicolaas A.P.
Published: March 2023

Expression of p53 with western blot in cell cultures and with immunohistochemistry in patient biopsies after radiation and hyperthermia treatment.
Supplementary Figure S3. The tumor microenvironment in Sparcl1-/- models. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Authors: Hurley Paula J. , Hughes Robert M. , Simons Brian W. , Huang Jessie , Miller Rebecca M. , Shinder Brian , Haffner Michael C. , Esopi David , Kimura Yasunori , Jabbari Javaneh , Ross Ashley E. , Erho Nicholas , Vergara Ismael A. , Faraj Sheila F. , Davicioni Elai , Netto George J. , Yegnasubramanian Srinivasan , An Steven S. , Schaeffer Edward M.
Published: March 2023

Supplementary Figure S3
Supplementary Table S3 from Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study
Authors: Bae Sajin , Ulrich Cornelia M. , Neuhouser Marian L. , Malysheva Olga , Bailey Lynn B. , Xiao Liren , Brown Elissa C. , Cushing-Haugen Kara L. , Zheng Yingye , Cheng Ting-Yuan David , Miller Joshua W. , Green Ralph , Lane Dorothy S. , Beresford Shirley A.A. , Caudill Marie A.
Published: March 2023

ORs (95% CIs) of CRC by quartile of plasma DMG:betaine ratio.
Supplemental Figure 3 from CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110
Authors: Hu Shanhu , Danilov Alexey V. , Godek Kristina , Orr Bernardo , Tafe Laura J. , Rodriguez-Canales Jaime , Behrens Carmen , Mino Barbara , Moran Cesar A. , Memoli Vincent A. , Mustachio Lisa Maria , Galimberti Fabrizio , Ravi Saranya , DeCastro Andrew , Lu Yun , Sekula David , Andrew Angeline S. , Wistuba Ignacio I. , Freemantle Sarah , Compton Duane A. , Dmitrovsky Ethan
Published: March 2023

Supplemental Fig. S3. (A) Schematic diagram showing the relationship between CDK2, CP110, activated KRAS and anaphase catastrophe. (B) Engineered overexpression of CP110 was detected in A549, Hop62, H522 and H460 cells (versus control transfectants) using anti-HA antibody after 24 and 48 hours of transfection. A representative immunoblot for each cell line is displayed.
Supplementary Table S1 from Neuroendocrine Transdifferentiation in Human Prostate Cancer Cells: An Integrated Approach
Authors: Cerasuolo Marianna , Paris Debora , Iannotti Fabio A. , Melck Dominique , Verde Roberta , Mazzarella Enrico , Motta Andrea , Ligresti Alessia
Published: March 2023

Supplementary Table S1. Topology-based pathway analysis.
Supplementary Figure S2 from Neuroendocrine Transdifferentiation in Human Prostate Cancer Cells: An Integrated Approach
Authors: Cerasuolo Marianna , Paris Debora , Iannotti Fabio A. , Melck Dominique , Verde Roberta , Mazzarella Enrico , Motta Andrea , Ligresti Alessia
Published: March 2023

Supplementary Figure S2. PCA derived scores and loadings plot displaying sample projections of (A) NMR polar spectra, (B) NMR lipid extracts and (C) PCR transcripts values.
Supplementary Figure S1 from Neuroendocrine Transdifferentiation in Human Prostate Cancer Cells: An Integrated Approach
Authors: Cerasuolo Marianna , Paris Debora , Iannotti Fabio A. , Melck Dominique , Verde Roberta , Mazzarella Enrico , Motta Andrea , Ligresti Alessia
Published: March 2023

Supplementary Figure S1. Non-linear regression of experimental data showing LNCaP cells differentiation rate at different androgen levels. Data fit obtained with the Ricker function.
Supplementary Figure Legend from miR-25 Modulates Invasiveness and Dissemination of Human Prostate Cancer Cells via Regulation of αv- and α6-Integrin Expression
Authors: Zoni E. , van der Horst G. , van de Merbel A.F. , Chen L. , Rane J.K. , Pelger R.C.M. , Collins A.T. , Visakorpi T. , Snaar-Jagalska B.E. , Maitland N.J. , van der Pluijm G.
Published: March 2023

Supplementary Figure Legend. Legend for Supplementary Figures S1-S2.
Supplementary Figures S1-S6 from Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition
Authors: Soucheray Margaret , Capelletti Marzia , Pulido Inés , Kuang Yanan , Paweletz Cloud P. , Becker Jeffrey H. , Kikuchi Eiki , Xu Chunxiao , Patel Tarun B. , Al-shahrour Fatima , Carretero Julián , Wong Kwok-Kin , Jänne Pasi A. , Shapiro Geoffrey I. , Shimamura Takeshi
Published: March 2023

NSCLC harboring EGFR kinase domain mutation develops EGFR TKI resistance with mesenchymal phenotype (S1); Chronic exposure of HCC4006 cells to TGFβ1 promotes EMT and gefitinib resistance (S2); Chronic EGFR inhibition in EGFR mutant NSCLC cells promotes TGFβ1 secretion and SMAD pathway activation (S3); Concurrent EGFR and TGFβR inhibition prevents mesenchymal transition but does not avert emergence of EGFR TKI resistance (S4); AZD9291 treatment induces significant apoptosis in HCC4006GeSB-R cells with acquired T790M mutation (S5); Distribution of cells harboring T790M in PC9 and HCC4006 cells and STR analysis for HCC4006 cells and HCC4006 gefitinib resistant cells (S6).
Supplementary Table S5 from Activation Status of the Pregnane X Receptor Influences Vemurafenib Availability in Humanized Mouse Models
Authors: MacLeod A. Kenneth , McLaughlin Lesley A. , Henderson Colin J. , Wolf C. Roland
Published: March 2023

Pharmacokinetic parameters of vemurafenib in huPXR/huCAR/huCYP3A4/3A7 mice pre-treated with RIF or PB.
Supplemental Methods and Figure Legends from ErbB3–ErbB2 Complexes as a Therapeutic Target in a Subset of Wild-type BRAF/NRAS Cutaneous Melanomas
Authors: Capparelli Claudia , Rosenbaum Sheera , Berman-Booty Lisa D. , Salhi Amel , Gaborit Nadège , Zhan Tingting , Chervoneva Inna , Roszik Jason , Woodman Scott E. , Davies Michael A. , Setiady Yulius Y. , Osman Iman , Yarden Yosef , Aplin Andrew E.
Published: March 2023

Supplemental Methods and Figure Legends
Supplementary Table S1 from Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications
Authors: Gámez-Pozo Angelo , Berges-Soria Julia , Arevalillo Jorge M. , Nanni Paolo , López-Vacas Rocío , Navarro Hilario , Grossmann Jonas , Castaneda Carlos A. , Main Paloma , Díaz-Almirón Mariana , Espinosa Enrique , Ciruelos Eva , Fresno Vara Juan Ángel
Published: March 2023

Supplementary Table S1. MaxQuant proteinGroups info and LFQ data for each sample.
Supplementary Figures S1-S7 from PLK1 Phosphorylates PAX3-FOXO1, the Inhibition of Which Triggers Regression of Alveolar Rhabdomyosarcoma
Authors: Thalhammer Verena , Lopez-Garcia Laura A. , Herrero-Martin David , Hecker Regina , Laubscher Dominik , Gierisch Maria E. , Wachtel Marco , Bode Peter , Nanni Paolo , Blank Bernd , Koscielniak Ewa , Schäfer Beat W.
Published: March 2023

Supplementary Figures S1-S7. Establishment of screening approach (S1); BI 2536 causes apoptosis and cell cycle arrest (S2); PLK1 phosphorylates PAX3-FOXO1 in vitro (S3); PLK4 is overexpressed in tumor biopsies (S4); PLK1 expression does not correlate with MIB1 expression in tumor biopsies (S5); PLK4 silencing reduces PAX3-FOXO1 activity (S6); PLK1 inhibition causes NMYC degradation (S7).
Supp. Figure 1 from LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
Authors: Prunier Chloé , Josserand Véronique , Vollaire Julien , Beerling Evelyne , Petropoulos Christos , Destaing Olivier , Montemagno Christopher , Hurbin Amandine , Prudent Renaud , de Koning Leanne , Kapur Reuben , Cohen Pascale A. , Albiges-Rizo Corinne , Coll Jean-Luc , van Rheenen Jacco , Billaud Marc , Lafanechère Laurence
Published: March 2023

Analysis of LIMK1 expression in different breast cancer cell lines.
Supplemental Figure 5 from CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy
Authors: Escamilla Jemima , Schokrpur Shiruyeh , Liu Connie , Priceman Saul J. , Moughon Diana , Jiang Ziyue , Pouliot Frederic , Magyar Clara , Sung James L. , Xu Jingying , Deng Gang , West Brian L. , Bollag Gideon , Fradet Yves , Lacombe Louis , Jung Michael E. , Huang Jiaoti , Wu Lily
Published: March 2023

Time course of treatment response to ADT in CWR22Rv1 orthotopic tumors.
Supplemental Methods from Cell Division Patterns in Acute Myeloid Leukemia Stem-like Cells Determine Clinical Course: A Model to Predict Patient Survival
Authors: Stiehl Thomas , Baran Natalia , Ho Anthony D. , Marciniak-Czochra Anna
Published: March 2023

Supplemental Methods. Detailed derivation and calibration of mathematical model.
Supplemental Figure 1 from Cell Division Patterns in Acute Myeloid Leukemia Stem-like Cells Determine Clinical Course: A Model to Predict Patient Survival
Authors: Stiehl Thomas , Baran Natalia , Ho Anthony D. , Marciniak-Czochra Anna
Published: March 2023

Supplemental Figure 1. The figure depicts fit of model to individual patients' marrow blast counts.
Supplementary video 2 from Three-Dimensional Breast Cancer Models Mimic Hallmarks of Size-Induced Tumor Progression
Authors: Singh Manjulata , Mukundan Shilpaa , Jaramillo Maria , Oesterreich Steffi , Sant Shilpa
Published: March 2023

MCF7 600 μm microtumor crawling out of the microwell
Supplementary Tables S1-S4 from Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy
Authors: McDaniel Andrew S. , Hovelson Daniel H. , Cani Andi K. , Liu Chia-Jen , Zhai Yali , Zhang Yajia , Weizer Alon Z. , Mehra Rohit , Feng Felix Y. , Alva Ajjai S. , Morgan Todd M. , Montgomery Jeffrey S. , Siddiqui Javed , Sadis Seth , Bandla Santhoshi , Williams Paul D. , Cho Kathleen R. , Rhodes Daniel R. , Tomlins Scott A.
Published: March 2023

Clinicopathologic data for all profiled penile squamous cell carcinoma (PeSCCA) samples ; Sequencing data for all profiled penile squamous cell carcinoma (PeSCCA) samples ; Detailed somatic variant information from PeSCCA profiled by next generation sequenicng ; PeSCCA HPV genotyping and p16 immunohistochemistry (IHC) results .
Supplementary Figure 2 from Ibrutinib Exerts Potent Antifibrotic and Antitumor Activities in Mouse Models of Pancreatic Adenocarcinoma
Authors: Massó-Vallés Daniel , Jauset Toni , Serrano Erika , Sodir Nicole M. , Pedersen Kim , Affara Nesrine I. , Whitfield Jonathan R. , Beaulieu Marie-Eve , Evan Gerard I. , Elias Laurence , Arribas Joaquín , Soucek Laura
Published: March 2023

Ibrutinib and cromolyn treatment prevent mast cell degranulation in the tumor stroma.
Supplementary Figs. S1-S8 and Table S1 from RIP1 Kinase Is an Oncogenic Driver in Melanoma
Authors: Liu Xiao Ying , Lai Fritz , Yan Xu Guang , Jiang Chen Chen , Guo Su Tang , Wang Chun Yan , Croft Amanda , Tseng Hsin-Yi , Wilmott James S. , Scolyer Richard A. , Jin Lei , Zhang Xu Dong
Published: March 2023

Supplementary Figs. S1-S8 and Table S1 Supplementary Materials and Methods - The primers used for qPCR. Supplementary Fig. S1. Quantitation of RIP1 expression in melanocytic tumors. Supplementary Fig. S2. Melanocytes of different origins express lower levels of RIP1 than melanoma cells. Supplementary Fig. S3. Overexpression of RIP1 triggers cell death independently of its kinase domain. Supplementary Fig. S4. NF-kB is constitutively activated in melanoma cells. Supplementary Fig. S5. RIP1 overexpression triggers moderate reduction in melanocyte viability independently of caspases. Supplementary Fig. S6. RIP1 mRNA expression and its gene copy number variations in fresh melanoma isolates. Supplementary Fig. S7. The turnover rates of RIP1 mRNA are comparable between melanoma cells and melanocytes. Supplementary Fig. S8. Overexpression of RIP1 reverses reduction in NF-kB activation and melanoma cell proliferation caused by knockdown of TNFR1. Supplementary Table S1. Summary of melanocytic tumors and their expression levels of RIP1.
Supplementary Table S1 from Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
Authors: Mazzocca Antonio , Dituri Francesco , De Santis Flavia , Filannino Addolorata , Lopane Chiara , Betz Regina C. , Li Ying-Yi , Mukaida Naofumi , Winter Peter , Tortorella Cosimo , Giannelli Gianluigi , Sabbà Carlo
Published: March 2023

List of genes up-regulated in LPAR6 knocked down cells.
Supplemental Figure 4 from Glioblastomas Require Integrin αvβ3/PAK4 Signaling to Escape Senescence
Authors: Franovic Aleksandra , Elliott Kathryn C. , Seguin Laetitia , Camargo M. Fernanda , Weis Sara M. , Cheresh David A.
Published: March 2023

No co-localization of integrin β3 with phospho-PAK1
Supplemental Table S1 from PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease
Authors: Li Zejuan , Chen Ping , Su Rui , Hu Chao , Li Yuanyuan , Elkahloun Abdel G. , Zuo Zhixiang , Gurbuxani Sandeep , Arnovitz Stephen , Weng Hengyou , Wang Yungui , Li Shenglai , Huang Hao , Neilly Mary Beth , Wang Gang Greg , Jiang Xi , Liu Paul P. , Jin Jie , Chen Jianjun
Published: March 2023

List of the 1,190 genes that are expressed at a significantly higher level in Group 1 than in both Groups 2 and 3.
Supplementary Table S2 from Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas
Authors: Hilvo Mika , de Santiago Ines , Gopalacharyulu Peddinti , Schmitt Wolfgang D. , Budczies Jan , Kuhberg Marc , Dietel Manfred , Aittokallio Tero , Markowetz Florian , Denkert Carsten , Sehouli Jalid , Frezza Christian , Darb-Esfahani Silvia , Braicu Elena Ioana
Published: March 2023

Results of statistical tests for all metabolites in serum samples.
supplemental Figure 1 from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: March 2023

Activin A does not change the expression of CD25 on CD8 and CD4 T-cells in vitro.
Supplementary Figure 4 from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: March 2023

Recombinant BAFF, but not recombinant APRIL, up-regulates survival of T-cells.
Supplemental Table SI from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: March 2023

Activin A treatment does not alter expression of common cytokines in DC
Table S8 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: March 2023

Ingenuity Pathway Analysis on genes with ERalpha, FOXA1 or both in the gene body or within 20 kb upstream from the Transcriptional Start Site.
Supplemental Figure 3 from BAFF and APRIL from Activin A–Treated Dendritic Cells Upregulate the Antitumor Efficacy of Dendritic Cells In Vivo
Authors: Shurin Michael R. , Ma Yang , Keskinov Anton A. , Zhao Ruijing , Lokshin Anna , Agassandian Marianna , Shurin Galina V.
Published: March 2023

Recombinant APRIL (B), but not recombinant BAFF (A), stimulates proliferation of T-cells.
Supplemental Figure Legends from SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation
Authors: Bilir Birdal , Osunkoya Adeboye O. , Wiles W. Guy , Sannigrahi Soma , Lefebvre Veronique , Metzger Daniel , Spyropoulos Demetri D. , Martin W. David , Moreno Carlos S.
Published: March 2023

Supplemental Figure Legends
Figure S5 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: March 2023

RT-PCR analysis of 20 transcription factors in four tamoxifen-associated endometrial tumors and Ishikawa cells. Corresponding primers can be found in supplementary table S6.
Supplementary Methods and Figure Legends from STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis
Authors: Jones Laura M. , Broz Miranda L. , Ranger Jill J. , Ozcelik John , Ahn Ryuhjin , Zuo Dongmei , Ursini-Siegel Josie , Hallett Michael T. , Krummel Matthew , Muller William J.
Published: March 2023

Supplementary Methods and Figure Legends
Supplementary Table and Figure Legends from Control of PD-L1 Expression by Oncogenic Activation of the AKT–mTOR Pathway in Non–Small Cell Lung Cancer
Authors: Lastwika Kristin J. , Wilson Willie , Li Qing Kay , Norris Jeffrey , Xu Haiying , Ghazarian Sharon R. , Kitagawa Hiroshi , Kawabata Shigeru , Taube Janis M. , Yao Sheng , Liu Linda N. , Gills Joell J. , Dennis Phillip A.
Published: March 2023

Supplementary Table and Figure Legends
Supplementary Figure S3 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: March 2023

Gene expression profiling of dermal wound macrophages & monocytes
Supplementary Figure 1 from The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia
Authors: Baker Adele , Gregory Gareth P. , Verbrugge Inge , Kats Lev , Hilton Joshua J. , Vidacs Eva , Lee Erwin M. , Lock Richard B. , Zuber Johannes , Shortt Jake , Johnstone Ricky W.
Published: March 2023

Supplementary Figure 1. In vitro combination studies of dinaciclib and other therapeutics against MLL-AF9;NRASG12D leukemia.
Supplementary Figure Legends from The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis
Authors: Astudillo Luisana , Da Silva Thiago G. , Wang Zhiqiang , Han Xiaoqing , Jin Ke , VanWye Jeffrey , Zhu Xiaoxia , Weaver Kelly , Oashi Taiji , Lopes Pedro E.M. , Orton Darren , Neitzel Leif R. , Lee Ethan , Landgraf Ralf , Robbins David J. , MacKerell Alexander D. , Capobianco Anthony J.
Published: March 2023

Description of the contents of supplementary figures 1, 2 and 3.
Supplementary Figure 2 from The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis
Authors: Astudillo Luisana , Da Silva Thiago G. , Wang Zhiqiang , Han Xiaoqing , Jin Ke , VanWye Jeffrey , Zhu Xiaoxia , Weaver Kelly , Oashi Taiji , Lopes Pedro E.M. , Orton Darren , Neitzel Leif R. , Lee Ethan , Landgraf Ralf , Robbins David J. , MacKerell Alexander D. , Capobianco Anthony J.
Published: March 2023

IMR-1 inhibits tumor growth in OE19 xenograft tumor.
Supplementary Table S1 from Splenic Marginal Zone Granulocytes Acquire an Accentuated Neutrophil B-Cell Helper Phenotype in Chronic Lymphocytic Leukemia
Authors: Gätjen Marcel , Brand Franziska , Grau Michael , Gerlach Kerstin , Kettritz Ralph , Westermann Jörg , Anagnostopoulos Ioannis , Lenz Peter , Lenz Georg , Höpken Uta E. , Rehm Armin
Published: March 2023

Tumor-induced down- and upregulations of genes in the stroma.
Supplementary figures 1 and 3-6 from Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17
Authors: Hu Dong G. , Selth Luke A. , Tarulli Gerard A. , Meech Robyn , Wijayakumara Dhilushi , Chanawong Apichaya , Russell Roslin , Caldas Carlos , Robinson Jessica L.L. , Carroll Jason S. , Tilley Wayne D. , Mackenzie Peter I. , Hickey Theresa E.
Published: March 2023

Supplementary Figure 1. Correlation plots depicting the relationship between UGT2B15 and UGT2B17 mRNA expression in breast cancer. Supplementary Figure 3. Steroid-mediated regulation of GREB1, UGTB215 and UGTB17 in MCF7 cells. Supplementary Figure 4. Effect of ERα, FOXA1 or AR knockdown on UGT2B15 and UGT2B17 mRNA expression in MCF7 cells. Supplementary Figure 5. Genome browser images of showing FOXA1, ERα and AR chromatin occupancy at the UGT2B15 and UGT2B17 promoters in ZR75-1 and MCF7 cells. Supplementary Figure 6. Regulation of UGT2B15 and UGT2B17 mRNA expression by the AR agonist Enobosarm in MCF7 cells (A and B) and steroid-mediated regulation of UGT2B15 and UGT2B17 mRNA expression in normal breast tissues (C).
Figure S6 from Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer
Authors: Li Bo , Ni Chonghaile Triona , Fan Yue , Madden Stephen F. , Klinger Rut , O'Connor Aisling E. , Walsh Louise , O'Hurley Gillian , Mallya Udupi Girish , Joseph Jesuchristopher , Tarrant Finbarr , Conroy Emer , Gaber Alexander , Chin Suet-Feung , Bardwell Helen A. , Provenzano Elena , Crown John , Dubois Thierry , Linn Sabine , Jirstrom Karin , Caldas Carlos , O'Connor Darran P. , Gallagher William M.
Published: March 2023

Validation of MYC and TP53 genes as prognostic markers in TNBC
Table S3 from Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers
Authors: Yau Edwin H. , Kummetha Indrasena Reddy , Lichinchi Gianluigi , Tang Rachel , Zhang Yunlin , Rana Tariq M.
Published: March 2023

Table showing the genes targeted in the secondary sgRNA library screen
Supplementary file 1 from The SWI/SNF Complex Protein Snr1 Is a Tumor Suppressor in Drosophila Imaginal Tissues
Authors: Xie Gengqiang , Chen Hanqing , Jia Dongyu , Shu Zhiqiang , Palmer William Hunt , Huang Yi-Chun , Zeng Xiankun , Hou Steven X. , Jiao Renjie , Deng Wu-Min
Published: March 2023

Supplementary file 1
FigureS3 from Inhibition of Nr4a Receptors Enhances Antitumor Immunity by Breaking Treg-Mediated Immune Tolerance
Authors: Hibino Sana , Chikuma Shunsuke , Kondo Taisuke , Ito Minako , Nakatsukasa Hiroko , Omata-Mise Setsuko , Yoshimura Akihiko
Published: March 2023

Potent anti-tumor immune responses were induced in Nr4a-DcKO mice
FigureS2 from Inhibition of Nr4a Receptors Enhances Antitumor Immunity by Breaking Treg-Mediated Immune Tolerance
Authors: Hibino Sana , Chikuma Shunsuke , Kondo Taisuke , Ito Minako , Nakatsukasa Hiroko , Omata-Mise Setsuko , Yoshimura Akihiko
Published: March 2023

Treg-specific deletion of Nr4a1 and Nr4a2 attenuated Treg cell suppressive activities
Supplementary Materials and Methods from Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer
Authors: Russo Joshua W. , Gao Ce , Bhasin Swati S. , Voznesensky Olga S. , Calagua Carla , Arai Seiji , Nelson Peter S. , Montgomery Bruce , Mostaghel Elahe A. , Corey Eva , Taplin Mary-Ellen , Ye Huihui , Bhasin Manoj , Balk Steven P.
Published: March 2023

The file contains supplemental details related to real-time quantitative PCR, RNA sequencing data analysis, meta-analysis of DDP4 expression and AR score across multiple prostate cancer datasets, immunohistochemistry analysis (AR, AR-V7, pAR(S81), and PSA expression), and promoter methylation analysis. It also contains 9 references related to these methods.
Supplementary figure legends from Oncogenic Kinase–Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem–like Cells
Authors: Zhou Zhifen , Li Min , Zhang Lin , Zhao Hong , Şahin Özgür , Chen Jing , Zhao Jean J. , Songyang Zhou , Yu Dihua
Published: March 2023

Description of supplementary figures
Supplementary table S2 from Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells
Authors: Grasset Eloise M. , Bertero Thomas , Bozec Alexandre , Friard Jonas , Bourget Isabelle , Pisano Sabrina , Lecacheur Margaux , Maiel Majdi , Bailleux Caroline , Emelyanov Alexander , Ilie Marius , Hofman Paul , Meneguzzi Guerrino , Duranton Christophe , Bulavin Dmitry V. , Gaggioli Cedric
Published: March 2023

Quantification of organotypic invasion assay screening.
Table S3 from Gaussian Mixture Models for Probabilistic Classification of Breast Cancer
Authors: Prabakaran Indira , Wu Zhengdong , Lee Changgun , Tong Brian , Steeman Samantha , Koo Gabriel , Zhang Paul J. , Guvakova Marina A.
Published: March 2023

Table S3. The summary of testing normality in cancer data sets.
Supplementary Data Figures 1-8 from Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress
Authors: Young Lucy A. , O'Connor Lenka Oplustil , de Renty Christelle , Veldman-Jones Margaret H. , Dorval Thierry , Wilson Zena , Jones David R. , Lawson Deborah , Odedra Rajesh , Maya-Mendoza Apolinar , Reimer Corinne , Bartek Jiri , Lau Alan , O'Connor Mark J.
Published: March 2023

This file contains all supplementary figures. Figure 1-7 provide additional analysis of genetic and cell features associated with AZD6738 and AZD1775 activity in DLBCL cell lines, including immunochemistry, immunoblots, immunofluorescence and flow cytometry data to further support the conclusions made from data presented in the main manuscript. Fig 8 provides tumour volume and body weight measurements for individual animals used in the in vivo studies.
Figure S3 from Identification of Coding and Long Noncoding RNAs Differentially Expressed in Tumors and Preferentially Expressed in Healthy Tissues
Authors: Unfried Juan P. , Serrano Guillermo , Suárez Beatriz , Sangro Paloma , Ferretti Valeria , Prior Celia , Boix Loreto , Bruix Jordi , Sangro Bruno , Segura Víctor , Fortes Puri
Published: March 2023

Pan-cancer analysis of mRNA donor tissue. A. Pie chart showing the mRNA donor tissue of the top 100 upregulated mRNAs in all (TCGA) or in each of the tumors examined. B. Graphs showing the percentage of tissue-donated mRNAs in each tumor versus all mRNAs donated by the tissue. The average value is indicated by a discontinuous line.
Supplementary Figures from Histone-Related Genes Are Hypermethylated in Lung Cancer and Hypermethylated HIST1H4F Could Serve as a Pan-Cancer Biomarker
Authors: Dong Shihua , Li Wei , Wang Lin , Hu Jie , Song Yuanlin , Zhang Baolong , Ren Xiaoguang , Ji Shimeng , Li Jin , Xu Peng , Liang Ying , Chen Gang , Lou Jia-Tao , Yu Wenqiang
Published: March 2023

Supplementary Figures S1-S9
Supplementary tables from A Novel MYCN-Specific Antigene Oligonucleotide Deregulates Mitochondria and Inhibits Tumor Growth in MYCN-Amplified Neuroblastoma
Authors: Montemurro Luca , Raieli Salvatore , Angelucci Silvia , Bartolucci Damiano , Amadesi Camilla , Lampis Silvia , Scardovi Anna Lisa , Venturelli Leonardo , Nieddu Giammario , Cerisoli Lucia , Fischer Matthias , Teti Gabriella , Falconi Mirella , Pession Andrea , Hrelia Patrizia , Tonelli Roberto
Published: March 2023

supplementary tables Supplementary Table 1: List of cell lines used in this study. Supplementary Table 2: List of the primers used in this study for quantitative Real Time PCR. Supplementary Table 3: Table showing the EC50 effect for BGA001 and BGA002 (MYCN mRNA, decrease in cell viability, N-myc protein and apoptosis induction in Kelly and SK-N-BE(2)c cell lines). Supplementary Table 4: List of genes present in the Mitochondrial-related signature in alphabetical order. Supplementary Table 5: Table summarizing principal patient features and their cluster attribution. More extensive information can be seen at http://www.ebi.ac.uk/arrayexpress; accession: E-MTAB-1781. Supplementary Table 6: Table summarizing the mitoscore and its components for each gene of the mitochondrial signature; genes are order based on decreasing mitoscore. Supplementary Table 7: List of the top 200 differentially expressed genes between Cluster 1 (left) and Cluster 2 (right) Supplementary Table 8: List of Cluster 1 and Cluster 2 associated genes used for the pathway network analysis. Supplementary Table 9: List of the ClueGo pathways obtained from the pathway network analysis.
Figure S5 from The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis
Authors: Taylor Sarah E. , O'Connor Caitlin M. , Wang Zhizhi , Shen Guobo , Song Haichi , Leonard Daniel , Sangodkar Jaya , LaVasseur Corinne , Avril Stefanie , Waggoner Steven , Zanotti Kristine , Armstrong Amy J. , Nagel Christa , Resnick Kimberly , Singh Sareena , Jackson Mark W. , Xu Wenqing , Haider Shozeb , DiFeo Analisa , Narla Goutham
Published: March 2023

PP2A Aα-, C-, and B55α-subunit protein abundance in PPP2R1A wildtype and P179-mutant patient EMCA tumor samples
Figure S1 from The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis
Authors: Taylor Sarah E. , O'Connor Caitlin M. , Wang Zhizhi , Shen Guobo , Song Haichi , Leonard Daniel , Sangodkar Jaya , LaVasseur Corinne , Avril Stefanie , Waggoner Steven , Zanotti Kristine , Armstrong Amy J. , Nagel Christa , Resnick Kimberly , Singh Sareena , Jackson Mark W. , Xu Wenqing , Haider Shozeb , DiFeo Analisa , Narla Goutham
Published: March 2023

Supplemental data on PPP2R1A mutation in endometrial cancer (EMCA) and clinical and genomic features of P179 mutation-positive EMCA tumors, from the cBioportal cancer database
Supplementary Data from Heparanase Accelerates Obesity-Associated Breast Cancer Progression
Authors: Hermano Esther , Goldberg Rachel , Rubinstein Ariel M. , Sonnenblick Amir , Maly Bella , Nahmias Daniela , Li Jin-Ping , Bakker Marinka A.H. , van der Vlag Johan , Vlodavsky Israel , Peretz Tamar , Elkin Michael
Published: March 2023

Supplementary Methods and Supplementary References
Supplementary Figure S3 from YAP1 Mediates Resistance to MEK1/2 Inhibition in Neuroblastomas with Hyperactivated RAS Signaling
Authors: Coggins Grace E. , Farrel Alvin , Rathi Komal S. , Hayes Colin M. , Scolaro Laura , Rokita Jo Lynne , Maris John M.
Published: March 2023

Figure S3 shows that growth rates of NLF YAP1-null clones are slower than NLF sgCon.
Supplementary Table S2 from Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis
Authors: Eckhardt Bedrich L. , Cao Yuan , Redfern Andrew D. , Chi Lap Hing , Burrows Allan D. , Roslan Suraya , Sloan Erica K. , Parker Belinda S. , Loi Sherene , Ueno Naoto T. , Lau Peter K. H. , Latham Bruce , Anderson Robin L.
Published: March 2023

BMP4 expression in human breast cancer
Supplementary Figure S2 from Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis
Authors: Eckhardt Bedrich L. , Cao Yuan , Redfern Andrew D. , Chi Lap Hing , Burrows Allan D. , Roslan Suraya , Sloan Erica K. , Parker Belinda S. , Loi Sherene , Ueno Naoto T. , Lau Peter K. H. , Latham Bruce , Anderson Robin L.
Published: March 2023

Figure S2 shows the effect of BMP4 on the in vitro properties of tumour cells and response of tumours in vivo.
Supplementary Materials and Methods from P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors
Authors: Romagnani Andrea , Rottoli Elsa , Mazza Emilia Maria Cristina , Rezzonico-Jost Tanja , De Ponte Conti Benedetta , Proietti Michele , Perotti Michela , Civanelli Elisa , Perruzza Lisa , Catapano Alberico L. , Baragetti Andrea , Tenedini Elena , Tagliafico Enrico , Falzoni Simonetta , Di Virgilio Francesco , Norata Giuseppe Danilo , Bicciato Silvio , Grassi Fabio
Published: March 2023

Supplementary Materials and Methods
Supplementary Data 1 from An LTR Retrotransposon-Derived Long Noncoding RNA lncMER52A Promotes Hepatocellular Carcinoma Progression by Binding p120-Catenin
Authors: Wu Yangjun , Zhao Yiming , Huan Lin , Zhao Jingjing , Zhou Yuqiang , Xu Linguo , Hu Zhixiang , Liu Yizhe , Chen Zhiao , Wang Lu , Huang Shenglin , He Xianghuo , Liang Linhui
Published: March 2023

Full scan of all the western blots in the main figures.
Supplementary Data Fig1-4 and methods from An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling
Authors: Wijaya Juwina , Vo BaoHan T. , Liu Jingjing , Xu Beisi , Wu Gang , Wang Yao , Peng Junmin , Zhang Jin , Janke Laura J. , Orr Brent A. , Yu Jiyang , Roussel Martine F. , Schuetz John D.
Published: March 2023

Supplementary Figure1: ABCC4 amount, regulation and its effect on medulloblastoma patient survival. Supplementary Figure 2: Knockdown of mouse and human ABCC4 suppresses SHH signaling. Supplementary Figure 3: ABCC4 does not influence nuclear and cytosolic cAMP but alters PKA-mediated phosphorylation of GLI2, Gli3 and SUFU. Supplementary Figure 4: Correlation between ABCC4 level and patient survival of neuroblastoma, adrenocortical carcinoma, liver hepatocellular carcinoma, and breast cancer.
Supplementary Table 1 from Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma
Authors: Tian Chenxi , Öhlund Daniel , Rickelt Steffen , Lidström Tommy , Huang Ying , Hao Liangliang , Zhao Renee T. , Franklin Oskar , Bhatia Sangeeta N. , Tuveson David A. , Hynes Richard O.
Published: March 2023

List of qPCR primers.
Supplementary Data from Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression
Authors: Midorikawa Yutaka , Yamamoto Shogo , Tatsuno Kenji , Renard-Guillet Claire , Tsuji Shingo , Hayashi Akimasa , Ueda Hiroki , Fukuda Shiro , Fujita Takanori , Katoh Hiroto , Ishikawa Shumpei , Covington Kyle R. , Creighton Chad J. , Sugitani Masahiko , Wheeler David A. , Shibata Tatsuhiro , Nagae Genta , Takayama Tadatoshi , Aburatani Hiroyuki
Published: March 2023

Supplementary Figure legends
Table S2 from Chromothripsis in Human Breast Cancer
Authors: Bolkestein Michiel , Wong John K.L. , Thewes Verena , Körber Verena , Hlevnjak Mario , Elgaafary Shaymaa , Schulze Markus , Kommoss Felix K.F. , Sinn Hans-Peter , Anzeneder Tobias , Hirsch Steffen , Devens Frauke , Schröter Petra , Höfer Thomas , Schneeweiss Andreas , Lichter Peter , Zapatka Marc , Ernst Aurélie
Published: March 2023

Chromothripsis scoring by visual and algorithm-based approaches
Supplementary Methods from A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer
Authors: Mosa Mohammed H. , Michels Birgitta E. , Menche Constantin , Nicolas Adele M. , Darvishi Tahmineh , Greten Florian R. , Farin Henner F.
Published: March 2023

In this file we provide additional methods for the described procedures including organoid transduction/transgenesis, biological image processing and image quantification. We provide in-depth information on the RNA sequencing protocol used and describe details of subsequent bioinformatic workflows including 'NicheNet' analysis. Also we provide details on the in silico analysis of CRC patient data and Kaplan-Meier analysis.
Table S1 from Targeting Adenosine with Adenosine Deaminase 2 to Inhibit Growth of Solid Tumors
Authors: Wang Lin , Londono Luz M. , Cowell Jessica , Saatci Ozge , Aras Mertkaya , Ersan Pelin G. , Serra Sara , Pei Hong , Clift Renee , Zhao Qiping , Phan Kim B. , Huang Lei , LaBarre Michael J. , Li Xiaoming , Shepard H. Michael , Deaglio Silvia , Linden Joel , Thanos Christopher D. , Sahin Ozgur , Cekic Caglar
Published: March 2023

Supplementary Table S1
Supplementary Figure 2 from CKAP2L Promotes Non–Small Cell Lung Cancer Progression through Regulation of Transcription Elongation
Authors: Monteverde Tiziana , Sahoo Sudhakar , La Montagna Manuela , Magee Peter , Shi Lei , Lee Dave , Sellers Robert , Baker Alexander R. , Leong Hui Sun , Fassan Matteo , Garofalo Michela
Published: March 2023

CKAP2L regulates cell migration and its expression correlates with tumour progression of human LuAd