bluuebunny/crossref_metadata_2025 huggingface dataset:
LBMON65 Generation Of Serum Insulin Like Growth Factor -1 (IGF-1) Normative Data According To Age, Tanner Staging & Bone Age In Healthy Indian Children And Adolescents With Two Different Assays: The Germinative Study
Authors: Teja Ravi , Dutta Pinaki , Korbonits Márta , Marwaha Raman K , Malhotra Bhanu , Rastogi Ashu , Mukherjee Soham , Pal Rimesh , Bhansali Anil , Bhadada Sanjay , Walia Rama , Das Liza , Aggarwal Arun , Monaghan Phillip , James Peter
Published: November 2022

Context

To diagnose and monitor GH-related disorders, serum IGF-I is a cornerstone, but Indian ethnicity based data, following consensus criteria for establishment of normative data are not available.

Objectives

To generate normative IGF-I data for chronological age (CA), Tanner stage and bone age (BA) [Greulich & Pyle (GP)] for both genders. Setting and Participants: We conducted a cross-sectional epidemiological study for Indian children (age 5-18 years) that included 2226 apparently normal subjects (1145 males; 1081 females). We used robust clinical exclusion criteria initially and later statistically we removed outliers separately for Age,Tanner Stage & Bone age using software SPSS 26. 0. Outcome Measures:: Serum IGF-I (ng/ml) using the Roche ECLIA & Immunodiagnostic Systems & Immunoassay System (IDS iSYS) were measured and normative data for 2.5th, 5th,10th, 25th, 50th (median), 75th, 90th, 95th and 97.5th centiles were generated.

Results

Age- and gender-specific serum IGF-I normative data generated from a uniquely large cohort reflected various patterns. With Roche assay, females (n=910) had IGF-I median peak at 13 years (356.85) [BA (n=804) at 14 years (401.5 ng/mL)] and & Tanner (n = 936) stage IV (368) while males (n=959) had median peak at 14 years (329.5) [BA (n=906) at 15 years (351 ng/mL)] & Tanner (n = 986) stage III (311. 0). With IDS iSYS assay, females had IGF-I median peak at Age (n=913) 13 years (397.5), Tanner (n=941) stage IV (418.5) and GP BA (n=843) 14 years (448.5) and males had median peak at Age (n=974) 14 years (376), Tanner (n=1003) stage III (367) and GP BA (n=909) 15-16 years (383). Females had earlier rise & peak and higher IGF-I values with both assays. In Tanner-specific data maximum difference noticed between stage II and III in both genders with both assays. On comparison of both assays, IGF-1 median peak was achieved at similar ages and Tanner stage but all the values are higher with IDS iSYS assay. When reviewed published literature on Caucasians, females had IGF-I median peak at 15 years (300.1) and Tanner stage III (382.8) and males had median peak at 15 years (318.3) and Tanner stage IV (439). The Indian & Caucasian IGF-1 normative data clearly demonstrates that every ethnicity has a unique pattern of growth.

Conclusions

The normative data on serum IGF-I are ethnicity-specific and it will improve the diagnostic utility of IGF-I in evaluation and management of growth disorders in Indian Children. Using both age- and Tanner stage-specific normative data simultaneously can improve diagnostic work-up.

Presentation: Monday, June 13, 2022 12:30 p.m. - 2:30 p.m.
LBODP075 Vanishing Pituitary Macroadenoma
Authors: Naik Vaishali Shashikant
Published: November 2022

Introduction

-Clinical presentation of Pituitary macroadenoma and Lymphocytic hypophysitis may mimic each other. It is necessary to be cautious when one treats these patients and follow up with clinical response and hormonal and radiological evaluation is important to differentiate between the two pathologies.

Case presentation

Sixty years lady with no comorbidities presented with giddiness and vomiting for three days. She was found to have high blood pressure and was started on betablocker. This was followed by hypotension and bradycardia for which patient required admission. On admission she had persistent hypotension and bradycardia required inotropes for 48 hours. Her routine investigations were unremarkable but S. sodium was 117 (135-145 mEq/L). Endocrine reference was for persistent hyponatremia. History did not reveal any significant medical or surgical problems. She did not have headaches, visual complaints or polyuria. Clinical examination was unremarkable. Her hormonal profile was done and started on intravenous steroids. There was dramatic response to the steroid treatment. Her investigations - Urine spot Na 40 (more than 20meq/L), Urine specific gravity 1. 015 (1. 005-1. 030), Urine osmolarity 210.6mosm/kg of water (500-850) Serum osmolarity of 257.7 moms/kg(275- 295), Random bloodsugar 106 mg/dl(less than 140), Cortisol 1.91 mcg/dl (10-20), ACTH 5.59 pg/ml(10-60), Ft3 1.67pg/ml(2.3-4.1) Ft4 0.7 ng/dl(0.7-1.9) TSH 0. 05mIU/L(0.5-5. 0), Prolactin 12.5 ng/ml(less than 25), LH 1.58 IU/L(19.3-100) FSH 11.85 IU/L(25-130), uric acid 3.2 mg/dl (3.5-7.2), Glycosylated Hb 5.7% (less than 5.7),serum sodium 117 mEq/L(135-145), serum K+ 4.5 meq/L (3.6-5.2), serum creatinine 0.8 mg/dl (0.6-1.3), ACE levels 21.32 mcg/L(less than 40), antiTPO antibodies 1.82 IU/mL (less than 9), IGF1 23.6 ng/ml (55-165) . MRI pituitary showed a pituitary macroadenoma. Patient improved dramatically with intravenous steroids and thyroxine 50 mcg per day. She was discharged on oral steroids prednisolone 5 mg twice a day and thyroxine 50 mcg daily. Patient followed up after 6 weeks and was clinically stable and her Ft3 was 2.46 pg/ml and FT4 was 1. 06 ng/dl with 8 am Cortisol (without steroids) 16.3 mcg/dl and ACTH 54.4 pg/ml. Her MRI pituitary after 3 months showed a normal pituitary and clinically she was stable off steroids . She is coninued on thyroxine 50 mcg and is under regular follow up.

Conclusion

- A female patient who presented in adrenal crisis with central hypothyroidism with radiological evidence of a pituitary macroadenoma which vanished on treatment of steroids. Retrospectively it was probably Lymphocytic hypophysitis which recovered over 3 months. Her hormonal profile improved. It is important to have a clinical index of suspicion while treating a Pituitary macroadenoma which may masquerade a Lymphocytic hypophysitis as the natural course of disease and treatment is different in both.

Presentation: No date and time listed
Isabel de Velasco, menina deLas Meninas, y los indios del antiguo señorío de Zinacantán en 1642–1659
Authors: Obara-Saeki Tadashi
Published: November 2022

Este artículo muestra una relación que existió entre Isabel de Velasco, menina de Las Meninas, y los indios de Zinacantán, San Felipe, Ixtapa, Osumacinta y Simojovel de la provincia de Chiapas en Centroamérica. Cuando Isabel tenía tres años, sus padres obtuvieron la encomienda de estos cinco pueblos, y en otoño de 1659, su padre cubrió tres gastos relativos a la muerte y los funerales de Isabel con el dinero procedente de la renta de los tributos de aquellos indios. El caso de Isabel de Velasco y los indios de estos cinco pueblos nos permite entender de manera muy concreta una de las relaciones que se dieron entre la alta nobleza de Madrid y los indios de los reinos americanos a mediados del siglo xvii.
A Refuge from Science: The Practice and Politics of Rights in Brazil's Vaccine Revolt
Authors: Cantisano Pedro Jimenez
Published: November 2022

This article considers the rights-based opposition that helped fuel Rio de Janeiro's 1904 Vaccine Revolt. I argue that the revolt was embedded in sociolegal conflicts about the policing of homes. In the early twentieth century, empowered by new laws, public health agents invaded homes to disinfect them with sulfur to kill the mosquitoes that transmitted yellow fever, and to vaccinate residents against smallpox. An elite coalition invoked the constitutional right to the home's inviolability against state interference in this private space. For working-class people, this rights language resonated with long-lasting struggles for inclusion and equality. Since the nineteenth century, they had associated their homes with freedom, honor, and autonomy. Moreover, judicial records reveal that a less diverse group composed of immigrants, property owners, and labor leaders requested court orders to stop forced residential disinfections. This article shows how resistance in courts and on the streets mutually fueled each other.
Poverty Alleviation from the Margins: Mexico's IMSS-COPLAMAR as a Challenge to Global Health and Economic Models, 1979–1989
Authors: Soto Laveaga Gabriela
Published: November 2022

A 1970s and 1980s poverty alleviation program, IMSS-COPLAMAR, challenged universal definitions of poverty as well as health models for rural areas while proffering a distinctly Mexican alternative. Yet this solution, broadly painting rural dwellers as marginados (marginalized), focused on need-based definitions of social exclusion and thus incongruously erased ethnic diversity while celebrating Indigenous forms of healing. Indeed, linking notions of poverty to health programs redefined poverty in the late twentieth century as an economically preventable ailment. More problematically, the term marginados tended to flatten the complex identities of the rural poor. Despite these faults, the program was groundbreaking and inventive in its conception. At its core, this article shows how radically innovative and socially inclusive domestic programs that emerged in the late twentieth century from the so-called developing world found it difficult to compete against—and survive—prescriptive solutions pushed by international organizations, especially at the dawn of neoliberal reforms.
I Am Not the Zygote I Came from because a Different Singleton Could Have Come from It
Authors: Lee Chunghyoung
Published: November 2022

Many people believe that human beings begin to exist with the emergence of the 1-cell zygote at fertilization. I present a novel argument against this belief, one based on recently discovered facts about human embryo development. I first argue that a human zygote is developmentally plastic: A zygote that naturally develops into a singleton (i.e., develops into exactly one infant/adult without twinning) might have naturally developed into a numerically different singleton. From this, I derive the conclusion that a human infant or adult is numerically distinct from the zygote she came from and so did not begin to exist at fertilization. This implies that a zygote does not have a “future like ours” and strongly suggests that it is not a human being.
A Forgotten Family Portrait
Authors: Cecil Elizabeth A.
Published: November 2022

Ancient Daśapura was the site of an internally complex Śaiva religious community. The Aulikara rulers used Śaivism as a political idiom to celebrate military might and royal power. Their ministers, the Naigamas, promoted an irenic vision that praised Śiva as a source of protection and prosperity. Attention to those expressions of Śaivism enable us to contextualize one of Daśapura's most famous, yet enigmatic, works of art: an ithyphallic male figure depicted with a double phallus (ca. sixth c. ce). To date, the sculpture has remained impossible to place within the greater artistic landscape of the region. This study proposes a resolution by showing that the icon was conceived as part of a triad of sculptures that included Śiva's wife, Pārvatī, and their son, Skanda. The images of Śiva and Skanda are displayed at the Bhopal Museum, and while their similarities have been noted in previous studies, they have not been viewed as part of a set. The reason for this is their separation from an unpublished Pārvatī that currently is displayed in the Mandasor Archaeological Museum and identified as a yakṣī. When viewed as part of a triad, the double-phallus figure is transformed from an iconographic puzzle into an innovative visual strategy to reconcile what might seem opposing facets of a divine persona—that is, the ascetic and the family man. By presenting these icons as a “family portrait,” this study recontextualizes important works of art from early India and initiates broader considerations of the political and religious ideologies that inspired their production.
Art-Historical Fiction or Fictional Art History?
Authors: Park J. P.
Published: November 2022

In 1634 Zhang Taijie (b. 1588) published a woodblock edition of Baohuilu (A Record of Treasured Paintings), an extensive catalog of a massive painting collection he claimed to have built. This work would seem to be a useful resource for historians of Chinese art since it provides accounts of paintings by artists whose works are no longer extant. But there is one major problem: the book is a forgery. What is more, Zhang also forged paintings to match the documentation he created, so he could also profit from trading in them. Interestingly, the book also echoes unfounded claims registered in art-historical writings of the time, wherein leading critics and connoisseurs, including Dong Qichang (1555–1636), propounded completely contrived arguments by which they tried to establish legitimate lineages in Chinese art. Such propositions represent, borrowing from Eric Hobsbawm's insight, a kind of “invented tradition,” a fictional history of practice and artifact that runs as some thought it ought to have, rather than as it did. By looking into all the three major components of forgeries in early modern China that are referenced throughout Zhang Taijie's catalog—(1) fabricated texts, (2) forged paintings, and (3) fake histories/theories—this paper aims to explain how Baohuilu facilitated Zhang's candid desire for fame and profit in the booming art market of the time, while unveiling certain cultural, social, and genealogical anxieties and tensions negotiated in the form of art-historical theories.
“Structure and Subject Matter” at Dunhuang
Authors: Linrothe Rob
Published: November 2022

Michelle Wang's Maṇḍalas in the Making is a groundbreaking treatment of mainly ninth- and tenth-century wall murals at Dunhuang making use of recent scholarship on early Esoteric Buddhist texts, teachers, and themes in Chinese and Tibetan sources. The review article assesses and extends the understanding and definitions of forms of mandala in India and China, recognizing the distinction between textual accounts of internal, visualized mandalas (bhāvyamaṇḍala), and the external, physical objects (lekhyamaṇḍala). Questions concerning the role(s) of the viewer and the purpose(s) of the Dunhuang shrines for the patrons and designers are also raised. For the patrons and designers, the shrines surely provided opportunities for acts of merit-making and expressions of gratitude for good fortune. For viewers and later visitors, were the shrines coded expressions of discursive Buddhist “meaning” and “repentance rituals,” as Wang mainly argues, or (perhaps also) locales for gestalt experience of the presence of consecrated deities? The attribution of the visual style to a Nepalese-derived Tibetan mode is also examined.
Urban Popular Economies
Authors:   The Urban Popular Economy Collective, Benjamin Solomon , Castronovo Alioscia , Cavallero Luci , Cielo Cristina , Gago Véronica , Guma Prince , Gupte Rupali , Habermehl Victoria , Salman Lana , Shetty Prasad , Simone AbdouMaliq , Smith Constance , Tonucci João
Published: November 2022

What is a life worth living and how is it concretely actualized by an urban majority making often unanticipated, unformatted uses of the urban to engender livelihoods in a dynamic and open-ended process? This is the key question undertaken in this collectively written piece. This means thinking about work, paid and unpaid, in ways that highlight the everyday practices of urban inhabitants as they put together territories in which to operate, which sustain their imaginations of well-being as part of a process of being with others—in households, neighborhoods, communities, and institutions. What is it that different kinds of workers have in common; what links them; where does the household begin and end; what is the difference between productive and reproductive work?
Αντιλαμβανόμενη ασφάλεια πολιτών και μειονότητες στην Ελλάδα
Authors: Μάλλιου Χριστίνα
Published: November 2022

Ο όρος ασφάλεια είναι πολυδιάστατος αλλά και απολύτως απαραίτητος για τις σύγχρονες κοινωνίες αφού συνδέεται με το επίπεδο ποιότητας ζωής. Η προσωπική, οικονομική, περιβαντολλογική-κλιματική, πολιτική, υγείας, ασφάλεια τροφίμων, ενέργειας, τηλεπικοινωνιών, κοινοτική και θεσμική είναι μόνο κάποιες από τις πτυχές της ανθρώπινης ασφάλειας. Το υψηλό επίπεδο ιεράρχησής της και η καλλιέργεια του αισθήματος ύπαρξης απειλής, παρείχε στις Κυβερνήσεις τη δυνατότητα να χρησιμοποιήσουν την ασφάλεια ως μέσο επιβολής μέτρων περιστολής ατομικών ελευθεριών που σε διαφορετικές περιπτώσεις θα ήταν αδιανόητη η εφαρμογή τους. Αναλογιζόμενοι όμως το πραγματικό ευρωπαϊκό όραμα για κοινή ευρωπαϊκή οικονομική και πολιτική γραμμή, την Ευρωπαϊκή ολοκλήρωση με άλλα λόγια, γίνεται αντιληπτή η σημαντική θέση που έχει το ζήτημα της ασφάλειας για τη Δημόσια Διοίκηση όχι μόνο στα στενά εθνικά όρια αλλά και σε ευρωπαϊκό επίπεδο. Το επικρατέστερο τρίπτυχο ασφάλειας που κυριαρχεί είναι η ασφάλεια από μετανάστες, Ρομά και τρομοκράτες. Οι πυλώνες αυτοί θα αναλυθούν στην παρούσα Διδακτορική Διατριβή μέσα από δευτερογενή δεδομένα αλλά και στατιστική επεξεργασία πρωτογενούς υλικού που συλλέχθηκε μετά από τη διανομή ερωτηματολογίου και μετέπειτα θα αξιολογηθεί η Δημόσια Διοίκηση για το μέχρι τώρα έργο της και θα διατυπωθούν βελτιωτικές προτάσεις χάραξης πολιτικής για το μέλλον.
Μελέτη της επίδρασης της χορήγησης του μονοκλωνικού αντισώματος antiCD20 στον αριθμό, τους υποπληθυσμούς και τη λειτουργία των Τ- λεμφοκυττάρων ασθενών με ρευματοειδή αρθρίτιδα
Authors: Μπούνια Κωνσταντίνα
Published: November 2022

Εισαγωγή : Στόχος της μελέτης ήταν η αξιολόγηση για πιθανές επιδράσεις της αγωγής με rituximab (RTX) στους υποπληθυσμούς των περιφερικών Th17 και Treg Τ λεμφοκυττάρων σε ασθενείς με ρευματοειδή αρθρίτιδα(ΡΑ) .Ασθενείς-Μέθοδοι : Αναλύσαμε 16 ασθενείς με ΡΑ που έλαβαν για πρώτη φορά RTX, 11 ασθενείς με ΡΑ που έλαβαν για πρώτη φορά abatacep(ABA), 11 ασθενείς με ΡΑ που ήδη λάμβαναν αγωγή, 8 ασθενείς με άλλες αυτοάνοσες παθήσεις που έλαβαν για πρώτη φορά RTX και 14 υγιείς εθελοντές. Τα Th17 (CD4+IL23R+IL-17A+) και τα Treg (CD4+CD25hiFoxP3+) κύτταρα εκτιμήθηκαν με κυτταρομετρία ροής.Αποτελέσματα : Τα Th17 κύτταρα από ασθενείς με ΡΑ ελαττώθηκαν σημαντικά τις εβδομάδες 8 και 16 μετά τη θεραπεία με RTX (μέση τιμή ± SEΜ: 3.01% ± 0.54℅ CD4+ κύτταρα την εβδ 0 vs. 1.53% ± 0.24℅ την εβδ 8 vs 1.10% ± 0.20℅ την εβδ 16, p = 0.0004). Οι μειώσεις των Th 17 ήταν πιο εμφανείς στους κλινικά ανταποκριθέντες ασθενείς (DAS28≤ 3.2) στους ACPA (+) και RF( -) ασθενείς. Τα Treg κύτταρα στην περιφέρεια παρέμειναν σταθερά σε αριθμό. Τα Th17 και Treg κύτταρα παρέμειναν αμετάβλητα μετά την αγωγή με ΑΒΑ αλλά και στις διαφορετικές χρονικές φάσεις της ΡΑ σε ασθενείς υπό άλλη αγωγή. Τα Treg αλλά όχι τα Th17 κύτταρα ελαττώθηκαν σημαντικά μετά την αγωγή με RTX σε ασθενείς με άλλα αυτοάνοσα νοσήματα (0.75% ± 0.16% την εβδ 0 vs. 0.43% ± 0.16% την εβδ 8, p = 0.033).Συμπέρασμα: Η Β-κυτταρική εξάλειψη που επάγεται από τη χορήγηση RTX σε ασθενείς με ΡΑ προκαλεί σημαντική ελάττωση των Th17 Τ κυττάρων αλλά δεν έχει καμία επίδραση στα Treg Τ κύτταρα. Αυτή η ελάττωση των Th17 T κυττάρων είναι πιο έκδηλη στους κλινικά ανταποκρινόμενους στην αγωγή με RTX, στους ACPA(+) και στους RF (-) ασθενείς με ΡΑ.
Τεχνητή νοημοσύνη
Authors: Παναγοπούλου Φερενίκη
Published: November 2022

H διατριβή αναλύει την έννοια της τεχνητής νοημοσύνης και την ηθικο-συνταγματική προβληματική που αυτή γεννά. Ιδιαίτερη έμφαση δίδεται στα ηθικο-συνταγματικά ζητήματα που αναδύονται εξ αιτίας διαφόρων εφαρμογών της, κάτι που έχει ως αποτέλεσμα να οδηγούμαστε σε έναν νέο ψηφιακό συνταγματισμό.Η εργασία διαρθρώνεται σε δύο βασικά μέρη. Στο γενικό μέρος επιχειρείται να ορισθεί η τεχνητή νοημοσύνη, αναλύονται κάποιες ενδεικτικές εφαρμογές, συζητείται η ηθική, φιλοσοφική και συνταγματική προβληματική και εξετάζεται κριτικά τόσο το κείμενο, όσο και το προτεινόμενο νομοθετικό πλαίσιο. Παράλληλα, εξετάζονται τα ζητήματα που αφορούν στην απόδοση ευθυνών σε σχέση με τις ενέργειες της τεχνητής νοημοσύνης, ενώ θίγεται και το ειδικό ζήτημα της αναγνωρίσεως νομικής προσωπικότητας σε μηχανές. Στο ειδικό μέρος συζητούνται τα συστήματα τεχνητής νοημοσύνης που σχετίζονται με την παροχή υπηρεσιών υγείας, τη διεξαγωγή εκλογών και την απονομή της δικαιοσύνης. Η συνολική έρευνα και η επιλογή των επί μέρους ζητημάτων οδηγεί σε έναν ψηφιακό συνταγματισμό, δηλαδή στη συνδιαμόρφωση ενός συνταγματικού πλαισίου από την τεχνολογία. Στη συνέχεια διατυπώνονται ορισμένες βασικές αρχές για την ορθολογική αξιοποίηση της τεχνητής νοημοσύνης. Στο τέλος εκτίθενται τα κεντρικά συμπεράσματα της μελέτης.
Media portrayal of vaccine: a content analysis of Vietnam online news about a pentavalent vaccine in the Expanded Program of Immunization.
Authors: Ha Nguyen Thanh , Chi Nguyen Thi Yen , Van Nuil Jennifer , Thwaites Louise , Chambers Mary
Published: November 2022

Background: Vaccine hesitancy has become a prominent public health concern, particularly within the coronavirus disease 2019 (COVID-19) pandemic context. Worries about vaccine side effects are often cited as a reason for hesitancy, while media reporting about this topic plays an important role in influencing the public’s perspectives about vaccines and vaccination. In Vietnam, during 2012-2013, there were several adverse events following immunization (AEFIs) of Quinvaxem– a pentavalent vaccine in the Expanded Immunization Program, which made big headlines in the media. Such incidences have contributed to changes in vaccination policies and influenced parents’ concerns to date.  This study explores the portrayal of Quinvaxem in Vietnam digital news during four periods marked by important events.

Methods: We performed quantitative and qualitative analysis with a coding framework to identify main content focus, sentiments towards Quinvaxem, and emotional tones in these articles.

Results: In total, we included 360 articles into analysis. The amount of news coverage about Quinvaxem increased after AEFIs happened, from 7 articles before AEFIs to 98 and 159 articles in the following periods when AEFIs and investigation into vaccine safety occurred. Most articles are neutral in titles (n=255/360) and content (n=215/360) towards Quinvaxem and do not convey emotional expressions (n=271/360). However, articles focusing on side effects contain negative sentiments and emotional expressions more frequently than articles of other contents while AEFIs details were conflicting across articles. Vaccine sentiments are provoked in the information about vaccine quality and safety, health authority, local delivery, and quoted vaccine opinions. Emotion-conveying elements in 89/360 articles included emotional wording and imagery and expressive punctuation.

Conclusions: The heterogeneity of information in online news may reinforce uncertainty about vaccine safety and decrease vaccine intention. Our results have important implications for vaccine communication, given the current plan of the Vietnamese government to roll out COVID-19 vaccination to younger children.
From Contextualizing to Context Theorizing: Assessing Context Effects in Privacy Research
Authors: Xu Heng , Zhang Nan
Published: November 2022

Over the past two decades, behavioral research in privacy has made considerable progress transitioning from acontextual studies to using contextualization as a powerful sensitizing device for illuminating the boundary conditions of privacy theories. Significant challenges and opportunities wait, however, on elevating and converging individually contextualized studies to a context-contingent theory that explicates the mechanisms through which contexts influence consumers’ privacy concerns and their behavioral reactions. This paper identifies the important barriers occasioned by this lack of context theorizing on the generalizability of privacy research findings and argues for accelerating the transition from the contextualization of individual research studies to an integrative understanding of context effects on privacy concerns. It also takes a first step toward this goal by providing a conceptual framework and the associated methodological instantiation for assessing how context-oriented nuances influence privacy concerns. Empirical evidence demonstrates the value of the framework as a diagnostic device guiding the selection of contextual contingencies in future research, so as to advance the pace of convergence toward context-contingent theories in information privacy.

This paper was accepted by Anindya Ghose, information systems.
Managing medical waste in humanitarian supply chains: lessons for healthcare services
Authors: Zarei Mohammad Hossein
Published: November 2022

This article sheds light on the issue of medical waste in humanitarian supply chains. The challenges of managing medical waste in the volatile humanitarian context will be discussed, along with ways to address these challenges using digital tools and technologies, inter-organisational collaboration and the ‘designing out’ of waste. This article will contextualise the lessons learnt from the humanitarian sector for healthcare service providers, such as NHS.
Comparative Assessment of Single and Mixed Photosensitizers using Erythrosin B and Tartrazine Yellow Dye System in Photogalvanic and Dye Sensitized Solar Cells
Authors: Soni Virendra , Mahavar Chanchal , Rajoriya Varsha , Genwa K. R.
Published: November 2022

To reduce costs, a low-cost thin-film solar cell technique known as the Dye Sensitized Solar Cell (DSSC)/Gratzel Cell emerged. DSSC is an easy to manufacture photovoltaic technique but lacks its stability and higher conversion efficiency factors. In this paper, to overcome these challenges and to keep the cost factor on trial, the photogalvanic cell was also studied using an H-shaped glass tube. Both DSSC and photogalvanic cells were studied using the dyes Erythrosin B, Tartrazine, and a mixture of Erythrosin B and Tartrazine. It was noticed that the solution of a “mixture of photosensitisers” gave the conversion efficiency(η) of solar light of 0.11% in DSSC with Dimethyl sulphoxide (DMSO) as solvent, whereas the same system gave the 0.6963% conversion efficiency(η) of solar light in a photogalvanic solar cell, which states that photogalvanic cells shows comparatively higher conversion efficiency than DSSC.
Comparative Investigation of Thermodynamic Parameters of Seafood Waste as an Inhibitor for Mild Steel Corrosion in Varied Acidic Concentration
Authors: M. Priya M. Priya , M. Senthil M. Senthil , Selvi S. Kalai , S. Ranjitha S. Ranjitha
Published: November 2022

Mild steel (MS) is the material that is frequently used in various sectors because of its specific properties like ductility and malleability, however it corrodes readily when exposed to corrosive environments. Inhibition is the best method to prevent corrosion, since it may be adjusted or added in place without interrupting a process. The present study focused on the thermal behavior of Crab Shell extract (CSE) as corrosion inhibitor on the surface of the MS in 0.5M and 1M sulphuric acid medium. Temperature study was employed to test the inhibitory action of the extract on MS using weight loss measurement. The effectiveness of inhibition declines with the rise of temperature. In 0.5M H2SO4 at 303K, the maximum efficiency was observed. The nature of adsorption in both the acidic medium follows El-Awady adsorption isotherm. The activation and thermodynamic study revealed that the reaction is spontaneous in nature. The inhibition process is endothermic which is confirmed by the positive enthalpy values.
A Low Cost and Nondestructive Micro-Pocket Meter on Chlorophyll Contents of Vegetable Leaves
Authors: Du Rongyu , Guo Wenchuan , Zhou Yihang , Cheng Jingliang , Zhu Xinhua
Published: November 2022

Highlights

A meter on the contents of chlorophyll a and b and total chlorophyll of vegetable leaves was developed.

Three LEDs as light sources and a light sensor to sense transmitted light through leaves.

The models to predict the chlorophyll contents were established using multiple linear regression.

The pocket detector makes chlorophyll content detection easy, fast, and in situ.

Abstract. Detecting the contents of chlorophyll (chlorophyll a, chlorophyll b) is important to instruct vegetable growth. However, the traditional spectrophotometry used in measuring these contents requires expensive equipment, is destructive, time-consuming, toxic (acetone), and unable to measure in situ. To make the detection nondestructive, quick, cheap, safe, and on-site, a low-cost micro-pocket photosynthetic chlorophyll content meter was developed in this study. The meter consisted of a micro-controller of STC12C5A60S2, three light-emitting diodes at 460, 660, and 980 nm, a digital light sensor, three keys, one organic light-emitting diode display, and a power supply unit. The software was developed by using the C language. The leaves of leaf lettuce, garden sass, and spinach were used as samples. The models used to predict the contents of chlorophyll a, chlorophyll b, and total chlorophyll, as well as SPAD values, were established based on the absorbance of vegetable leaves at three wavelengths by using the multiple linear regression method. The root-mean-squares errors of the developed meter for chlorophyll a, chlorophyll b, total chlorophyll, and SPAD value were 0.068 mg/g, 0.024 mg/g, 0.085 mg/g, and 1.7, respectively. The meter was small in size and low in cost. The contents of chlorophyll a, chlorophyll b, total chlorophyll, and SPAD value, could be given in 2 s. Keywords: Absorbance, Chlorophyll a, Chlorophyll b, Chlorophyll content, Pocket meter, SPAD.
Design and Testing of Water Jet-Based Fresh Lotus Seed Peeling Machine
Authors: Xu Xieqing , Ding Weimin , Sun Yuanhao
Published: November 2022

Highlights

Lotus seed coats are often peeled using water jets, which has not been studied in-depth.

A water jet-based lotus seed peeling system is proposed and investigated in detail.

Response surface method experiment was used to enhance peeling-machine performance.

Proposed system performs well in terms of cost, stability, and percentage of seed peeled and damaged.

Abstract. Lotus seed coats are often peeled using water jets. However, currently, existing fresh lotus seed peeling machines could process lotus seeds only if their size differences are small. Due to a lack of research on water jet operation parameters, the peeling process is often associated with a low percentage of seed peeled (PSP) and a high percentage of seed damage (PSD). A new type of water jet-based fresh lotus seed peeling machine was designed and tested to solve the aforementioned problems. Three-factor, three-level response surface method (RSM) was used in experiments to enhance peeling-machine performance, and quadratic polynomial regression equations were obtained via analysis of the experimental data. Results show that these independent variables had significant effects on PSP and PSD: water jet pressure (X1), water jet angle (X2), and processing speed (X3). Specifically, X1 and X2 had an interactive effect on PSD, whereas X1 and X3 both had a strong interactive effect on PSP and PSD. The optimal parameters were a water jet pressure of 0.60 MPa, water jet angle of 20°, and processing speed of 62 rpm, leading to predicted PSP and PSD of 93.13% and 1.65%, respectively (similar to the validation experimental PSP and PSD of 93.89% and 1.76%, respectively); thus, proving the accuracy of the RSM model. In general, the proposed peeling machine provided a high machine capacity (19.65 kg/h), a high percentage of seed peeled, and a low percentage of seed damaged, and all performance indices fulfilled the requirements for use. Keywords: Lotus seed, Parameter optimization, Peeling, Water jet.
A New Technique of Fixing Intra-articular Fractures of the Distal Humerus without Exposing the Ulnar Nerve by Posterior Approach
Authors: Pappu Rajasekhar , Vavilalaa Abhilash Rao , Reddy A V Gurava , Boddeda Sandeep , Reddy Kishan
Published: November 2022

Introduction: Distal humerus fractures constitute around 0.2 to 7% of all fractures, 30% of all umerus fractures, most common in young adults, are due to high energy trauma and in old age due to osteoporosis. A common step in all currently available approaches is to identify the ulnar nerve, expose, mobilise, and retract this from its surrounding bed or in situ release. Ulnar neuropathy is either observed immediately after surgery or delayed up to one year after surgery. We are describing a new posterior approach for intra-articular distal humerus fractures, where identification and retraction of the ulnar nerve are not required to fix the intra-articular fractures of the distal humerus, thereby avoiding injury to the ulnar nerve. Material and Methods: Seven patients with AO type B and C were treated using our new ulnar nerve-sparing approach between January 2017 and December 2019. Postoperatively, all the patients have been examined for ulnar neuropathy symptoms. Results: We have no ulnar nerve neuropathy either in the post-operative period or at 2 years follow-up (five cases were followed up for 2 years and two patients lost to follow-up after 6 months). At the end of 2 years, the mean range of motion achieved at elbow was 134°. The mean oxford elbow score was 45.2 (42–47). Heterotopic ossification and infection were not found in our cases. Conclusion: Our ulnar nerve-sparing approach for intra-articular fractures of distal third humerus by posterior approach helps in fixing articular fractures of distal humerus without exposing ulnar nerve during surgery without compromising on the exposure of fracture for fixation, thus reducing the chances of ulnar nerve injury and post-operative neuropathy.
Arthroscopic Reconstruction of ACL and LCL Tear with Combined Asymmetric Hamstring Graft Using Single Femoral Tunnel – A Case Report
Authors: Shah Malkesh D , Shah Bhagya R , Desai Sarvang , Patel Purvi
Published: November 2022

Introduction: Anterior cruciate ligament (ACL) injury is associated with various degrees of rotational deformity. About 15% have a positive pivot shift test after accurate ACL reconstruction. Unrepaired lateral collateral ligament (LCL) tear can lead to increase load on reconstructed ACL and lead to ligament failure. Case Report: We present a case of combined ACL with LCL tear treated arthroscopically using a single femoral tunnel and asymmetric combined semitendinosus and gracilis (STG) graft. The patient had full range of motion at the knee joint and was able to squat and sit cross-legged and was able to carry out activities of daily living at 8 months of follow-up. Conclusion: Our technique provides orthopedic surgeons with an alternative for combined ACL and LCL reconstruction with a single combined STG graft, thereby limiting additionally graft site morbidity and avoiding the need for allograft and preserving adequate femoral bone stock by preparing only a single femoral tunnel and thus limiting the cost to the patient using single implant for femur.
Eosinophilic Granuloma as a Solitary Lytic Lesion of the Cervical Spine in a Child
Authors: Jain Mantu , Parija Debasish , Padhi Somanath , Naik Suprava
Published: November 2022

Introduction:Eosinophilic granuloma (EG) is a type of Langerhan cell histiocytosis (LCH) with unknown etiology. This benign tumorous lytic lesion affects mainly children or young adults, causing bone destruction. Although, the flat or the long bones are commonly affected, localized spinal involvement in pediatric age group is rare. A thorough workup is therefore necessary for this condition, which may mimic other severe conditions. Case Report:A 10-year-old girl presented with neck pain for 4 months without any history of trauma, fever, or neurological weakness. An X-ray revealed radiolucency and sclerosis of the fifth cervical vertebral body, which was hypointense on T1 and heterogeneous on T2-weighted image, with mild peripheral enhancement on fat-suppressed post-contrast T1-weighted image. Biopsy histomorphology revealed a lymphohistiocytic lesion with scatted histiocytes with grooved nuclei, immunopositive for Langerin; thus consistent with LCH (EG). She was managed conservatively with a completely pain free course with full range of movement at 1-year follow-up. Her follow-up X-ray showed complete remodeling and ongoing fusion. Conclusion:EG should be considered as a differential diagnosis in the evaluation of solitary lytic lesion involving spine in pediatric age group. This, although self-resolving, may occasionally need surgical intervention with or without adjuvant therapy.
movimiento ecoalternativo y las redes de gobernanza en Guipúzcoa (País Vasco):
Authors: Bárcena Hinojal Iñaki , Ormazabal Gastón Andere , Larrinaga Arza Josu
Published: November 2022

Abstract:  En el presente artículo colectivo hemos pretendido analizar los cambios y la evolución, las emergencias y tambien las ausencias que se observan en el espectro ecologista de Gipuzkoa en la última década y  una década en que la actividad armada de ETA desaparece y en que el Gobierno de la provincia para a manos de de la coalición ( 2011-2015)  EH Bildu. En este novedoso contexto político e institucional hemos entrevistado, observado y analizado el movimiento ecologista guipuzcoano en sus dimensiones organizativas, sus alianzas y campañas, sus relaciones con la instituciones locales y con los medios de comunicación y sus relaciones internas ( diversidad, edades, sexo-genero, migrantes, idiomas, etc). Nos preguntabamos al inicio de nuestra investigación, dónde estaban los cambios y las emergencias de nuevas formas de pensar y actuar en los movimientos sociales de Gipuzkoa y en concreto del ecologismo y partiamos de la hipótesis de que había una hibridación entre un ecologismo clásico centrado en el NO a los proyectos desarrollados por empresas e instituciones  y otro que denominamos “ecoalternativo” más orientado a proponer nuevas formas de vivir, de actuar y de relacionarse hacia dentro y hacia fuera. Y en segundo lugar que la llegada al gobierno de la provincia de un grupo político más afín a los postulados ecologistas no ha supuesto el comienzo de una alianza fácil y segura con la institución, sino más bien un periodo donde el ecologismo ha descubierto sus debilidades y dificultades para trabajar institucionalmente.
Experiencia de maternidad en mujeres ejecutivas de lima metropolitana: un estudio cualitativo
Authors: Guevara-Delgado Jimena Lucero
Published: November 2022

Objetivo. Explorar la experiencia de maternidad en mujeres ejecutivas de Lima Metropolitana. Metodología. El estudio tiene un abordaje cualitativo fenomenológico, lo que permitió profundizar en cómo mujeres con altos cargos empresariales concilian su vida laboral y familiar. Fueron 7 participantes y los datos se obtuvieron a través de entrevistas semiestructuradas grabadas, previo consentimiento de las madres. Resultado. El análisis de datos se determinó bajo el diseño fenomenológico, el cual mostró que la experiencia de maternidad de estas mujeres está caracterizada por la presencia de sentimientos de culpa a la par del amor incondicional hacia su familia e hijos. Asimismo, las madres de este estudio cuentan con agentes auxiliares que les permiten armonizar el trabajo y la familia. Por una parte, sus parejas, quienes mantienen un rol activo en la crianza de los niños y labores domésticas; y, por la otra, el apoyo externo de niñeras, que suelen ser contratadas para realizar tareas tradicionalmente asignadas a la mujer. A su vez, se determinó que existen características contextuales que facilitan la convergencia entre la familia y el trabajo, como, por ejemplo, que los centros de trabajo donde laburan disponen de políticas flexibles, permitiéndoles cierta libertad sobre la ejecución y distribución de su tiempo. Conclusiones. Para un desarrollo profesional más equitativo de la mujer se requiere que haya una repartición más equitativa de responsabilidades. Al igual que los centros de laburo cada vez tengan más medidas para conciliar la maternidad con el trabajo.
Polymer negative curvature ring-core fiber for OAM modes guidance
Authors: Zhu Zheng-Han , Yan De-Xian , Li Xiang-Jun , Zhang Le , Qiu Guo-Hua , Li Ji-Ning
Published: November 2022

In this paper, a novel, to the best of our knowledge, polymer-based negative curvature ring-core fiber (NC-RCF) is proposed and investigated. The hollow-core NC-RCF is composed of TOPAS as background material. The inner and outer negative curvature structure layers are connected to the annular area, and the orbital angular momentum (OAM) modes can propagate in the annular core. In the frequency region of 1.0–1.5 THz, the designed NC-RCF can stably transmit 82 OAM modes. Investigation results indicate that the effective refractive index differences between the corresponding HE and EH modes are above

10

−
4

. The confinement losses of EH or HE modes are smaller than

10

−
8

d
B

/

m

, and the dispersion variations are lower than 0.31 ps/THz/cm. Effective mode areas are larger than

5.14

m
m

2

. Additionally, the highest mode purity of all vector modes is 99.78%. In addition, modal birefringence, also known as the walk-off length, has also been discussed. All these operation performances indicate that the designed NC-RCF make contributions to the optical communication systems.
Telehealth interventions for substance use disorders in low- and- middle income countries: A scoping review
Authors: Ojeahere Margaret Isioma , Kiburi Sarah Kanana , Agbo Paul , Kumar Rakesh , Jaguga Florence
Published: November 2022

The increasing prevalence and magnitude of harmful effects of substance use disorders (SUDs) in low- and middle-income countries (LMICs) make it imperative to embrace interventions which are acceptable, feasible, and effective in reducing this burden. Globally, the use of telehealth interventions is increasingly being explored as possible effective approaches in the management of SUDs. Using a scoping review of literature, this article summarizes and evaluates evidence for the acceptability, feasibility, and effectiveness of telehealth interventions for SUDs in LMICs. Searches were conducted in five bibliographic databases: PubMed, Psych INFO, Web of Science, Cumulative Index of Nursing and Allied Professionals and the Cochrane database of systematic review. Studies from LMICs which described a telehealth modality, identified at least one psychoactive substance use among participants, and methods that either compared outcomes using pre- and post-intervention data, treatment versus comparison groups, post-intervention data, behavioral or health outcome, and outcome of either acceptability, feasibility, and/or effectiveness were included. Data is presented in a narrative summary using charts, graphs, and tables. The search produced 39 articles across 14 countries which fulfilled our eligibility criteria over a period of 10 years (2010 to 2020). Research on this topic increased remarkably in the latter five years with the highest number of studies in 2019. The identified studies were heterogeneous in their methods and various telecommunication modalities were used to evaluate substance use disorder, with cigarette smoking as the most assessed. Most studies used quantitative methods. The highest number of included studies were from China and Brazil, and only two studies from Africa assessed telehealth interventions for SUDs. There has been an increasingly significant body of literature which evaluates telehealth interventions for SUDs in LMICs. Overall, telehealth interventions showed promising acceptability, feasibility, and effectiveness for SUDs. This article identifies gaps and strengths and suggests directions for future research.
Integrated xenosurveillance of Loa loa, Wuchereria bancrofti, Mansonella perstans and Plasmodium falciparum using mosquito carcasses and faeces: A pilot study in Cameroon
Authors: Pryce Joseph , Pilotte Nils , Menze Benjamin , Sirois Allison R. , Zulch Michael , Agbor Jean Pierre , Williams Steven A. , Wondji Charles S. , Reimer Lisa
Published: November 2022

Background

Community presence of loiasis must be determined before mass drug administration programmes for lymphatic filariasis and onchocerciasis can be implemented. However, taking human blood samples for loiasis surveillance is invasive and operationally challenging. A xenosurveillance approach based on the molecular screening of mosquitoes and their excreta/feces (E/F) forLoa loaDNA may provide a non-invasive method for detecting the community presence of loiasis.

Methods

We collected 770 wild mosquitoes during a pilot study in a known loiasis transmission area in Mbalmayo, Cameroon. Of these, 376 were preserved immediately while 394 were kept in pools to collect 36-hour E/F samples before processing. Carcasses and E/F were screened forL.loaDNA. To demonstrate this method’s potential for integrated disease surveillance, the samples were further tested forWuchereria bancrofti,Mansonella perstans, andPlasmodium falciparum.

Results

Despite limited sample numbers,L.loaDNA was detected in eight immediately-stored mosquitoes (2.13%; 95% CI 1.08 to 4.14), one carcass stored after providing E/F (0.25%; 95% CI 0.04 to 1.42), and three E/F samples (estimated prevalence 0.77%; 95% CI 0.15 to 2.23%).M.perstansandP.falciparumDNA were also detected in carcasses and E/F samples, whileW.bancroftiDNA was detected in E/F. None of the carcasses positive for filarial worm DNA came from pools that provided a positive E/F sample, supporting the theory that, in incompetent vectors, ingested parasites undergo a rapid, complete expulsion in E/F.

Conclusions

Mosquito xenosurveillance may provide a useful tool for the surveillance of loiasis alongside other parasitic diseases.
Chronic pain: Evidence from the national child development study
Authors: Blanchflower David G. , Bryson Alex
Published: November 2022

Using data from all those born in a single week in 1958 in Britain we track associations between short pain and chronic pain in mid-life (age 44) and subsequent health, wellbeing and labor market outcomes in later life. We focus on data taken at age 50 in 2008, when the Great Recession hit and then five years later at age 55 in 2013 and again at age 62 in 2021 during the Covid pandemic. We find those suffering both short-term and chronic pain at age 44 continue to report pain and poor general health in their 50s and 60s. However, the associations are much stronger for those with chronic pain. Furthermore, chronic pain at age 44 is associated with a range of poor mental health outcomes, pessimism about the future and joblessness at age 55 whereas short-duration pain at age 44 is not. Pain has strong predictive power for pain later in life: pain in childhood predicts pain in mid-life, even when one controls for pain in early adulthood. Pain appears to reflect other vulnerabilities as we find that chronic pain at age 44 predicts whether or not a respondent has Covid nearly twenty years later.