bluuebunny/crossref_metadata_2025 huggingface dataset:
Faktor Risiko Kejadian Gastritis Pada Remaja Di Wilayah Pesisir Puskesmas Abeli Kota Kendari Tahun 2023
Authors: Nurlyana Firda , Sety La Ode Muhammad , Handayani Listy
Published: December 2023

Gastritis merupakan proses inflamasi pada lapisan mukosa dan sub mukosa lambung. Penyakit gastritis menempati urutan ke 1 jumlah penyakit terbanyak di Puskesmas Abeli tahun 2021. Jenis penelitian ini adalah observasional analitik dengan pendekatan case control study. Penelitian ini bertujuan untuk mengetahui dan menganalisis faktor risiko asupan energi dan asupan protein terhadap kejadian penyakit gastritis pada remaja di wilayah pesisir Puskesmas Abeli tahun 2023. Populasi pada penelitian ini adalah seluruh pasien remaja di wilayah pesisir yang berobat di Puskesmas Abeli Kota Kendari pada bulan Januari - Oktober 2022 sebanyak 421 orang. Jumlah sampel sebanyak 104 (52 kasus dan 52 kontrol) dengan menggunakan teknik pengambilan simple random sampling. Hasil penelitian menunjukan bahwa tingkat kecukupan asupan energi (OR = 4,033, Cl 95% 1,587;10,251, p-value = 0,005) dan asupan protein (OR 2,956, Cl 95% 1,249;6,997, p-value = 0,021) merupakan faktor risiko kejadian penyakit gastritis di Puskesmas Abeli Kota Kendari tahun 2023. Berdasarkan penelitian ini, diharapkan agar masyarakat menjalankan program gerakan hidup sehat yang telah dibuat oleh pemerintah dan memperhatikan asupan gizi diri sendiri dan keluarga yang dikonsumsi setiap hari serta menerapkan perilaku hidup bersih dan sehat
Hubungan Durasi Bermain Game Online Dengan Kelelahan Mata Pada Remaja Di Desa Mekar Jaya Kabupaten Muna Barat Tahun 2023
Authors: Umayah Yul Fatul , Yusran Sartiah , Sety La Ode Muhammad
Published: December 2023

Keluhan kelelahan mata akibat terlalu lama di depan gadget dan gelombang elektromagnetik yang dihasilkan gadget menyebabkan radiasi dan bisa menganggu kesehatan mata. Teknologi internet saat ini selain untuk mencari informasi internet juga digunakan sebagai sarana hiburan yaitu game online, penelitian ini bertujuan untuk mngetahui hubungan rentang waktu bermain game online berbasis web dengan keluhan mata lelah pada remaja di Desa Mekar Jaya Kabupaten Muna Barat Tahun 2023. Penelitian ini menggunakan strategi kuantitatif dengan metedeologi cross sectional. Populasi penelitian ini adalah seluruh remaja usia 12-19 tahun yang berasal dari Desa Mekar Jaya Kabupaten Muna Barat contoh penilaian ini adalah dari 68 responden yang diperoleh melalui tes sesekali. Verifikasi informasi dilakukan secara univariat dan bivariat menggunakan chi-square .Hasil penelitian ini menunjukan bahwa tidak ada hubungan antara pengethuan game online dengan keluhan mata lelah pada remaja (p-value= 0,770) , kemudian tidak ada ubungan antara tingkat sikap bermain game online dengan keluhan mata lelah pada remaja ( p-value= 0,618) , ada hubungan antara jarak bermain game online dengan dengan ketegangan mata (p-value= 0,038) dan variabel durasi (p-value= 0,051) menunjukan adanya hubungan antara keluhan waktu saat bermain game online. Dapat disimpulkan bahwa variabel pengetahuan dan sikap tidak ada hubungan dengan bermain game online dengan keluhan kelelahan mata pada remaja di Desa Mekar Jaya kabupaten Muna Barat tahun 2023. Sedangkan variabel jarak dan durasi ada hubungan dengan bermain game online dengan keluhan kelelahan mata pada remaja di Desa Mekar Jaya Kabupaten Muna Barat tahun 2023.

Kata Kunci : Keluhan Kelelahan Mata, Game online, Pengeahuan, Sikap, Jarak, Durasi
Hubungan Pengetahuan, Sikap, Dan Tindakan Dengan Kejadian Demam Berdarah Dengue (Dbd) Di Wilayah Kerja Puskesmas Wua-Wua Kota Kendari Tahun 2023
Authors: Wati Fatma , Yasnani Yasnani , Irma Irma
Published: December 2023

Demam Berdarah Dengue (DBD) merupakan penyakit menular yang disebabkan oleh virus dengue, yang ditularkan melalui vektor nyamuk Aedes dari spesies Aedes aegypti atau Aedes albopictus dan dapat menyerang anak-anak maupun remaja. Data Dinas Kesehatan Kota Kendari menunjukkan pada tahun 2022, jumlah kasus DBD di Kota Kendari sebanyak 230 dengan jumlah kematian enam orang. Meskipun program pencegahan DBD sudah dilaksanakan oleh petugas kesehatan, namun belum mampu menurunkan angka penularan penyakit DBD. DBD merupakan penyakit berbasis lingkungan yang timbul akibat interaksi antara manusia, perilakunya, dan unsur lingkungan yang berpotensi menularkan penyakit. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan, sikap dan tindakan dengan kejadian Demam Berdarah Dengue (DBD) di wilayah kerja Puskesmas Wua-Wua Kota Kendari tahun 2023. Metode penelitian observasional analitik dengan desain cross-sectional. Populasi penelitian ini terdiri dari seluruh keluarga wilayah kerja Puskesmas Wua-Wua yang berjumlah 110 responden, dengan teknik penarikan sampel menggunakan teknik proportional random sampling. Data dikumpulkan melalui kuesioner, wawancara, pengukuran, dan observasi, kemudian dianalisis secara univariat dan bivariat. Hasil penelitian dengan uji chi-square menunjukkan bahwa tidak terdapat hubungan pengetahuan dengan kejadian DBD (p-value = 0,129), tidak terdapat hubungan sikap dengan kejadian DBD (p-value = 0,393), terdapat hubungan tindakan dengan kejadian DBD (p-value = 0,007). Dengan demikian, dapat disimpulkan bahwa pengetahuan dan sikap tidak memiliki hubungan dengan kejadian DBD, sedangkan tindakan memiliki hubungan dengan kejadian DBD.

Kata Kunci: pengetahua, sikap, tindakan, Demam Berdarah Dengue (DBD)
The inflammatory status of the intestine in premature infants depending on gestational age
Authors:   Department of Hospital Pediatrics with Traditional Medicine № 2, Pediatric Medical Institute, Republican Perinatal Center, Tashkent, Uzbekistan, Faziova Aziza , Akhmedova Dilorom ,   Department of Hospital Pediatrics with Traditional Medicine № 2, Pediatric Medical Institute, Republican Perinatal Center, Tashkent, Uzbekistan
Published: December 2023

Background and objectives (Aim). To identify the features of the inflammatory status of the intestine in premature infants depending on gestational age. Materials and methods. The study included 36 premature babies. All children were divided into two groups, according to gestational age (GA): group 1-12 newborns with GA of 22 (0/7) - 28 (6/7) weeks; and group 2-24 newborns with GA of 29(0/7) - 32(6/7) weeks. The exclusion criteria were: the presence of congenital malformations, septic conditions, surgical pathologies. Results. The level of fecal calprotectin, as well as CRP in the 1st group of children was significantly higher than in the 2nd group, which demonstrates an inverse relationship between the severity of inflammation and the gestational age of premature newborns: the lower the gestational age, the higher the rates of inflammation in the intestines. The permeability of the intestinal barrier was high in both groups, which was reflected in increased values of fecal alpha-antitrypsin on the 3rd and 14th days of the examination, and did not have statistically significant differences between the groups. Children of group 1 required longer treatment than children of group 2, both in the ICU. Clinical manifestations of digestive disorders in premature infants were manifested by decreasing in body weight gain, the appearance of discharge from the tube with pathological impurities, while no significant difference was found between the groups. Conclusions. Premature neonates less than 28 weeks of age show greater signs of acute inflammation in the intestinal tract.
Does vitreous galactin-3, copeptin and retina binding protein-4 concentrations change in diabetic retinopathy?
Authors: KONUK Şerife Gülhan , KILIÇ Raşit , ÇATAK Merve , GÜNEŞ Alper , KATAR Muzaffer
Published: December 2023

Aims: This study aimed to investigate whether the concentrations of Galactin-3 (G-3), Copeptin (CP) and Retina Binding Protein-4 (RBP-4) are affected in the vitreous humor of patients with diabetic retinopathy (DR). Methods: Thirty-six patients with diabetes mellitus (DM) were included in the study, consisting of 10 patients without DR and 26 patients with proliferative diabetic retinopathy (PDR). The control group comprised 15 patients who underwent vitrectomy for epiretinal membrane and macular hole surgeries. Vitreous CP, G-3, and RBP-4 concentrations were examined using the enzyme-linked immunosorbent assay (ELISA) method. The groups were compared internally Results: We did not observe any significant differences in the concentrations of G-3, CP and RBP-4 in the vitreous humor between diabetic patients and the control group (p=0.56, p=0.65 and p=0.11, respectively). When comparing vitreous samples of diabetic subgroups with and without DR findings to the control group, no significant differences were detected (p=0.51, p=0.66, and p=0.19, respectively). Conclusion: Our results indicate that the concentrations of G-3, CP, and RBP-4 in the vitreous humor remain unchanged in both diabetic patients and those with proliferative diabetic retinopathy (DRP).
The relationship between digital game addiction, cyberloafing, and psychological well-being in primary school students
Authors: ZİNCİR Serkan , SAPMAZ Fatma , HAMUTOĞLU Nazire Burçin , TOPAL Murat
Published: December 2023

Aims: Today, with the advances in technology, the use of devices such as computers, digital game consoles, phones, and tablets has also increased. However, with the widespread use of internet access, digital platforms have started to be used frequently in interpersonal interaction and relations. The use of digital games and the internet, where the user age is in a wide range, has decreased to very young ages, and the time spent by individuals in games and on the internet has gradually increased. In this context, the duration of stay in the digital environment can be seen as an important criterion in terms of addiction. Spending excessive time in the digital environment can cause individuals to be adversely affected by psychosocial aspects. The purpose of our study is to reveal the reasons for the complex and multifaceted relationship between cyberloafing, digital game addiction, and well-being, and to discuss potential solutions.
Methods: This study was designed as a cross-sectional study. The study group was formed of 1330 students in the second stage of primary education in grades, 5, 6, 7, and 8, in state schools. The sample Group consisted of 614 females and 716 males in almost the same age group. The game addiction scale, perceived cyberloafing scale, and psychological well-being scale were applied to students. The necessary permission to conduct the study was obtained from, then the data were collected in face-to-face interviews on a voluntary basis. The data obtained in this study were analyzed statistically using SPSS vn. 23 and AMOS 23 software.
Results: The Gaming Addiction Scale score was determined to be mean 42.09 for the whole group, 36.96 for females, and 46.96 for males. The Cyberloafing Scale score was determined to be a mean of 24.01 for the whole group, 21.94 for females, and 25.79 for males. The Psychological Well-Being Scale score was found to be a mean of 30.60 for the whole group, 32.02 for females and, 29.39 for males. A positive correlation was observed between gaming addiction and, cyberloafing, (p=0.00) and both of these conditions were determined to be negatively correlated with psychological well-being. (p=0.00)
Conclusion: Activities to support students’ psychological well-being can help prevent vicious cycles between cyberloafing, game addiction, and psychological well-being by contributing to controlling cyberloafing and game addiction tendencies.
LA CULTURA Y LAS OBLIGACIONES TRIBUTARIAS EN UNA EMPRESA PERUANA
Authors: Romero Carazas Rafael
Published: December 2023

Resumen
El presente articulo tiene como objetivo determinar la relación entre la cultura tributaria y las obligaciones tributarias en una empresa peruana. Respecto a la metodologí­a, se trabajó bajo el enfoque de articulo original, de í­ndole cuantitativo y correlacional, se utilizó la técnica de encuesta y se elaboraron dos cuestionarios para la recolección de datos, una para la variable cultura tributaria y una para la variable obligación tributaria que pasaron debidamente por confiabilidad de Alfa de Cronbach y por validación de juicio de expertos. Luego del procesamiento de datos mediante el programa SPPS versión 28, se concluye que al 0.05 de nivel de significancia, se obtuvo un coeficiente de correlación de Rho de Spearman = 0.735** interpretándose como relación positiva fuerte, con una Ï = 0.000 (Ï <0.05); esto significa que la cultura tributaria se relaciona con las obligaciones tributarias, en los comerciantes de venta de juguetes de la galerí­a coronel Mendoza en ciudad de Tacna 2020.
Estrés laboral y rendimiento laboral en el personal de enfermerí­a del Hospital II Tarapoto - EsSalud
Authors: Ramí­rez Gómez Guadalupe
Published: December 2023

Esta investigación se planteó como objetivo principal determinar la relación entre el estrés laboral y el rendimiento laboral en los profesionales de enfermerí­a del Hospital II Tarapoto - EsSalud; la metodologí­a utilizada fue una metodologí­a para una investigación de tipo básica, de enfoque cuantitativo, el nivel descriptivo correlacional y de diseño no experimental; la muestra fue intencional por conveniencia con un total de 150 participantes; la técnica para la recolección de los datos fue la encuesta y los instrumentos utilizados son fiables con un coeficiente Alfa de Cronbach de 0.902  y 0.760 respectivamente. Luego de procesar la información se determinó un p-valor = 0,000 indica que existe relación significativa y el Rho Spearman = ,402**.
Estrategia de comunicación creativa para identificar contenidos alterados vinculando la herramienta blockchain
Authors: ARAGON SANCHEZ MAURICIO ANTONIO
Published: December 2023

El periodismo se enfrenta al reto de combatir la desinformación en el ecosistema comunicativo actual. Una solución para reducir los riesgos informativos es el uso del blockchain, que garantiza la integridad de la información y previene su manipulación, Es por ello que acudir a sistemas de verificación, como puede ser el blockchain o cadena de bloques, contribuirí­a a reducir riesgos informativos. En este contexto, se ha creado NeoCápsula, un proyecto que une las bases de datos de los medios digitales en una sola fuente y permite identificar contenidos alterados. NeoCápsula presenta las imágenes originales y alteradas en una narrativa cross-media que certifica la fuente original y su autorí­a. Además, facilita al usuario la comprensión y uso del blockchain para detectar la alteración y contar con la trazabilidad de la autorí­a original de las imágenes digitales. Este proyecto de comunicación creativa contribuye a reducir la desinformación y garantizar la veracidad de la información en los medios digitales.
Gasto de inversión pública y crecimiento económico de la costa caribe colombiana.
Authors: Manjarres Tete Arleth
Published: December 2023

La presente investigación tiene como objetivo analizar el crecimiento económico del departamento del Atlántico en función de la inversión pública experimentada en ese territorio; considerándose el gasto público como un factor importante para la creación o mejoramiento de capacidades instaladas que contribuyen al desarrollo territorial en términos de crecimiento económico. Es un estudio con enfoque cuantitativo, de diseño no experimental, longitudinal, y documental, en el que se realiza un análisis sobre el comportamiento económico del territorio, haciendo uso del software estadí­stico Eviews, realizando una modelación a partir del gasto público del Atlántico en los periodos 2008 hasta 2021.  La investigación se sustenta en la revisión de bases de datos estadí­sticos del departamento del Atlántico contenidas en la plataforma DANE, TERRIDATA y CHIP de la Contadurí­a General de la Nación, al igual que informes generados por el gobierno departamental e informes nacionales sobre el comportamiento del Producto Interno Bruto para los años referenciados. Los resultaos muestran que el crecimiento económico del departamento presentó variaciones significativas en el periodo 2008-2021; con una tendencia hacia el alza desde el año 2008 hasta el año 2016, donde se hace un corte provocado por una baja en el precio de los hidrocarburos, reduciendo la oferta de la energí­a y bienes agrí­colas ocasionado por el fenómeno del niño y el paro del transporte de carga; continuando con decrecimiento económico hasta el año 2019, con diferencias entre Producto Interno Bruto (PIB) departamental para cada año que oscila entre 0,02% y 0,05%. En el año 2020, con la situación pandémica COVID-19, la economí­a del departamento se desestabiliza en los primeros meses del año; sin embargo, se aplican medidas para reactivar la economí­a, aumentando el PIB departamental. Se concluye que, durante el último año de análisis, el departamento hizo un esfuerzo para reactivar la economí­a, pero por las mismas condiciones de confinamiento obligatorio no se alcanzaron resultados contundentes.
PERCEPCIONES: LA SATISFACCIÓN LABORAL EN LA GESTIÓN DE PROYECTOS DE TRADUCCIÓN DURANTE LA PANDEMIA COVID-19
Authors: Cornejo Sánchez Jesus Fernando , Rí­os Valero Laura Lisset
Published: December 2023

Este estudio tuvo como objetivo comprender las experiencias vividas de los traductores de las agencias de traducción en torno a su satisfacción laboral en la gestión de proyectos de traducción durante la pandemia COVID-19. La investigación fue de enfoque cualitativo bajo el diseño fenomenológico. Los resultados indicaron que los traductores han tenido satisfacción laboral, motivados por el trabajo en equipo, la comunicación fluida entre los traductores y las gestoras y su adaptación a la alta gerencia, a pesar de la pandemia. Se concluye que cuando se privilegia una buena organización en cada una de las fases de la gestión de proyectos de traducción y se promueve la comunicación eficaz, los traductores valoran su labor como parte de un equipo de trabajo.
ARTICULACIÓN DE VARIABLES DEL COMPORTAMIENTO ORGANIZACIONAL EN FUNCIONARIOS PÚBLICOS PARA LOS PERíODOS 2019-2020
Authors: Chiang Vega Marí­a , Vergara Bustos Bárbara , Gómez Fuentealba Nelly
Published: December 2023

La emergencia sanitaria que enfrenta el mundo por COVID-19, presenta desafí­os y riesgos para las organizaciones. Esta investigación explica el efecto del compromiso organizacional, estrés laboral y conciliación trabajo-familia sobre la satisfacción laboral en funcionarios de una municipalidad chilena, antes y durante la pandemia. Por medio de una encuesta se obtuvo una muestra de 264 participantes. Para el estudio estadí­stico se utilizó un análisis de conglomerados que permitió identificar tres segmentos de individuos, donde para el año 2019 declaraban una percepción media en las variables y una percepción media-baja al año 2020. Por otro lado, los modelos de regresión confirman que las variables independientes afectan significativamente a la satisfacción laboral, contribuyendo en un 60% el año 2019 y 70% el año 2020 en explicar su variabilidad. Los resultados obtenidos confirman que existe un cambio en la percepción de las variables en estudio, entre un año y otro, quedando en manifiesto el impacto de la pandemia en los funcionarios públicos.
APPLICATION OF NATURAL LANGUAGE PARSING FOR IDENTIFYING NON-SURVEYED BOUNDARIES TOWARDS ENHANCED SYSTEMATIC LAND TITLING: RESULTS FROM PRELIMINARY EXPERIMENT
Authors: Odumosu Joseph O. , Nnam Victor C. , Kemiki Olurotimi A. , Abubarkar Abdulkadir , Oyebanji Michael A. , Babalola Sunday O.
Published: December 2023

The need for the adoption of systematic land titling (SLT) in Nigeria cannot be overemphasised. Nonetheless, the problems of speed and cost of geospatial data acquisition, as well as identification of non-surveyed boundaries, remain unresolved, impeding the effectiveness of SLT for non-surveyed boundaries. The integration of language into Artificial Intelligence (AI) has allowed Natural Language Parsing (NLP) to effectively serve as a tool for communication between humans and computer systems. This study presents preliminary results of testing a prototype application that utilises NLP to convert textual descriptions into graphic sketches as a tool towards the production of a-priori sketches that can aid SLT in non-surveyed boundaries. The study determines that NLP alone cannot be used to achieve the required accuracy in geospatial data for SLT; however, the study concludes that NLP can be integrated alongside other ancillary information to enhance SLT in peri-urban regions.
Early-time Ultraviolet and Optical Hubble Space Telescope Spectroscopy of the Type II Supernova 2022wsp
Authors: S. Vasylyev Sergiy , Vogl Christian , Yang 杨 Yi 轶 , Filippenko Alexei V. , Brink Thomas G. , Brown Peter J. , Matheson Thomas , Modjaz Maryam , Gal-Yam Avishay , Mazzali Paolo A. , de Jaeger Thomas , Patra Kishore C. , Stewart Gabrielle E.
Published: December 2023

We report early-time ultraviolet (UV) and optical spectroscopy of the young, nearby Type II supernova (SN) 2022wsp obtained by the Hubble Space Telescope (HST)/STIS at about 10 and 20 days after the explosion. The SN 2022wsp UV spectra are compared to those of other well-observed Type II/IIP SNe, including the recently studied Type IIP SN 2021yja. Both SNe exhibit rapid cooling and similar evolution during early phases, indicating a common behavior among SNe II. Radiative-transfer modeling of the spectra of SN 2022wsp with the TARDIS code indicates a steep radial density profile in the outer layer of the ejecta, a solar metallicity, and a relatively high total extinction of E(B − V) = 0.35 mag. The early-time evolution of the photospheric velocity and temperature derived from the modeling agree with the behavior observed from other previously studied cases. The strong suppression of hydrogen Balmer lines in the spectra suggests interaction with a preexisting circumstellar environment could be occurring at early times. In the SN 2022wsp spectra, the absorption component of the Mg ii P Cygni profile displays a double-trough feature on day +10 that disappears by day +20. The shape is well reproduced by the model without fine-tuning the parameters, suggesting that the secondary blueward dip is a metal transition that originates in the SN ejecta.
Mars-Crossing Minor Planet 2018 VL10: a Jupiter-family Comet Discovery via Citizen Science
Authors: Chandler Colin Orion , Oldroyd William J. , Trujillo Chadwick A. , Hsieh Henry H. , Burris William A. , Kueny Jay K. , DeSpain Jarod A. , Sedaghat Nima , Farrell Kennedy A. , Magbanua Mark Jesus Mendoza , Sheppard Scott S. , Mazzucato Michele T. , Bosch Milton K. D. , Shaw-Diaz Tiffany , Gonano Virgilio , Lamperti Al , da Silva Campos José A. , Goodwin Brian L. , Terentev Ivan A. , Dukes Charles J. A.
Published: December 2023

We announce the discovery of cometary activity emitting from minor planet 2018 VL10 in Dark Energy Camera images spanning from UT 2018 December 31 to UT 2019 March 3. The activity was identified by volunteers of our NASA Partner program Active Asteroids, a Zooniverse-hosted Citizen Science project designed to find previously unknown activity in known minor planets. Notably, 2018 VL10 crosses the orbits of Mars and Jupiter, and experiences close approaches of less than 0.5 au with both Earth and Jupiter. We classify 2018 VL10 as a member of the Jupiter-family comets, a group of objects especially important to understand because they hold important clues about the solar system volatile distribution, past and present.
Discovery of an Emission Nebula in Direction of γ Aql
Authors: Ziegenbalg Stefan
Published: December 2023

An emission nebula has been discovered in close apparent proximity to γ Aql (aka Tarazed). The diameter of the nebula is about

27
.′
4

and its center is about

7
′

away from γ Aql, which is known to be an X-ray source. However, γ Aql is most likely not the ionization source of the nebula. To my knowledge, this emission nebula has not been previously reported in the literature or on the Internet.
Synthesis of the 4400–4600 Å Spectral Range for the A2.5V star HD 176687 (ζ Sagitarii A)
Authors: Monier Richard
Published: December 2023

The synthesis of a high resolution high signal-to-noise spectrum of HD 176687 from 4400 to 4600 Å allows the determination of LTE abundances for magnesium, calcium, scandium, titanium, chromium, iron, nickel and barium. This A2.5V star has recently been found to be the most massive star in a triple system. Magnesium and calcium are found to have a solar abundance. Scandium and titanium are depleted by a factor of 0.50, chromium, nickel by a factor of 0.70 and iron by 0.60 compared to their respective solar abundances. Barium is overabundant by a factor of 7.50. The found abundances fit well within the abundance pattern previously found for a few normal A stars. There is no sign of the recently discovered companion to HD 176687 in the spectrum analyzed.
Baked before Breaking into Bits: Evidence for Atira-type Asteroid Splits
Authors: de la Fuente Marcos Carlos , de la Fuente Marcos Raúl
Published: December 2023

Current near-Earth asteroid orbital models cannot reproduce the observed populations close to the Sun. Supercatastrophic and tidal disruptions may explain the differences between theoretical models and observational data. Here, we explore the distributions of mutual nodal distances and the angular separation of perihelia of the known Atiras looking for evidence of past splittings. We find a number of pairs, trios, and one quartet of Atiras with mutual nodal distances as short as 0.001 au at the orbits of Mercury and Venus. The smallest of these highly correlated objects is 2023 WK3. Fragmentation or binary disruption may have triggered the recent formation of the unusual pair made of 594913 ’Ayló’chaxnim (2020 AV2) and 2012 VE46 with both mutual nodal distance and angular separation of perihelia in the first percentile of the distribution, making 2012 VE46 a robust candidate to being a former moon or piece of ’Ayló’chaxnim.
Refining the phylogeny and taxonomy of the apple tribe Maleae (Rosaceae): insights from phylogenomic analyses of 563 plastomes and a taxonomic synopsis of Photinia and its allies in the Old World
Authors: Wang Hui , Li Xiaoya , Jiang Yan , Zhang Yu , Jin Zetao , Ma Daikun , Liu Bing , Xu Chao , Ge BinJie , Wang Ting , Fan Qiang , Jin ShuiHu , Liu Guangning , Liu Binbin
Published: December 2023

This study addresses the longstanding absence of a comprehensive phylogenetic backbone for the apple tribe Maleae, a deficiency attributed to limited taxon and marker sampling. We conducted an extensive taxon sampling, incorporating 563 plastomes from a diverse range of 370 species encompassing 26 presently recognized genera. Employing a range of phylogenetic inference methods, including RAxML and IQ-TREE2 for Maximum Likelihood (ML) analyses, we established a robust phylogenetic framework for the Maleae tribe. Our phylogenomic investigations provided compelling support for three major clades within Maleae. By integrating nuclear phylogenetic data with morphological and chromosomal evidence, we propose an updated infra-tribal taxonomic system, comprising subtribe Malinae Reveal, subtribe Lindleyinae Reveal, and subtribe Vauqueliniinae B.B.Liu (subtr. nov.). Plastid phylogenetic analysis also confirmed the monophyly of most genera, except for Amelanchier, Malus, Sorbus sensu lato, and Stranvaesia. In addition, we present a comprehensive taxonomic synopsis of Photinia and its morphological allies in the Old World, recognizing 27 species and ten varieties within Photinia, three species and two varieties within Stranvaesia, and two species and three varieties within Weniomeles. Furthermore, we also lectotypified for 12 names and made two new combinations. This research fills critical gaps in the evolutionary history of the tribe Maleae and provides a refined taxonomic framework for future botanical studies.
Meeting Societal Needs for CNS Competencies
Authors: Lyon Brenda
Published: December 2023

The purpose of this paper is to contribute to the debate on whether or not the roles of the clinical nurse specialist (CNS) and nurse practitioner (NP) should be blended. In this paper I argue that the two roles should not be blended in masters degree programs for two reasons. First, societal needs for the advancement of nursing practice through the generation and utilization of nursing science and the provision of expert nursing care for highly complex problems have never been greater. Secondly, the two roles should not be blended because the competencies required for the two roles are more different than alike; hence the development of important competencies for one or both roles is lost in time-limited masters programs. Each of these reasons are discussed below.
Viva La Difference! The Nation Needs the Clinical Nurse Specialists and Nurse Practitioners as Separate Roles
Authors: Cukr Penny
Published: December 2023

Does there need to be one predominant advanced nursing role that merges the Nurse Practitioner (NP) and Clinical Nurse Specialist (CNS)? This paper examines the history of these two specialties within medical surgical arenas, their role differences along with legal and educational forces that influence this reoccurring question in an attempt to put this question into perspective.
Managed Care: Threat or Opportunity for Home Health?
Authors: Bonner Carolyn , Boyd Barbara
Published: December 2023

The focus of this article is a description of how two Northwest home health agencies, Group Health Cooperative and Providence Health System, have responded to the managed care environment. These agencies experience and response to the increased managed care provision of services is discussed. Strategies for providing quality home care at reduced care prices are described.
Redesign Not Downsize
Authors: Coulter Sharon
Published: December 2023

This article describes the redesign implemented by the Cleveland Clinic Foundation (CCF) in response to changes in the healthcare marketplace. In this CCF redesign process, we redefined RN roles and added two new roles: patient care technician and patient care service associate. Strategies used to facilitate this process on two acute care units are described; outcomes of this process are presented.
Licensure, Certification, and Accreditation
Authors: Barnum Barbara
Published: December 2023

This article provides an historical overview of the three major ways that nursing regulates the profession, its members, and their performance, i.e., licensure, certification, and accreditation. Each type of regulation mechanism is described and differences between them are explained. Current issues related to accreditation of schools of nursing are outlined.
Advancing circular economy principles through wild black soldier flies
Authors: Chineme Atinuke , Assefa Getachew , Herremans Irene M. , Wylant Barry , Shumo Marwa , Shoo Aliceanna , James Mturi , Ngalesoni Frida , Ndjovu Anthony , Mbuligwe Steve , Yhedgo Mike
Published: December 2023

Biowaste management poses a significant and widespread challenge. However, its consideration as a resource has led to the emergence of innovative and sustainable biowaste management techniques. One such promising solution is the use of black soldier flies (BSF) in biowaste treatment. This technique offers various advantages, such as the transformation of biowaste into versatile products that can be used in agriculture, horticulture, aquaculture, animal husbandry, pharmaceuticals and energy production. Despite significant research on different aspects of the BSF biowaste treatment system, none have explored the application of circular economy principles in low-income settings using naturally occurring BSF, i.e., free-range BSF. This article addresses the gap utilizing a mixed-method approach through a case study to achieve two objectives: the localization of the circular economy through co-production with a community group and the viable production of black soldier fly larvae (BSFL) and compost to meet the community's needs. Through collaboration, a successful circular economy was established as biowaste was transformed into products and safely reintroduced into the local biosphere. Performance indices used included BSFL nutritional composition, harvest rates and heavy metal absence.

Through community involvement, circular economy principles were effectively implemented to redirect a retail market's fruit and vegetable waste from the landfill. The free-range open system produced 19.15 kg of BSFL, with 44.34% protein content, 20.6% crude fat and zero heavy metals. These outcomes align with existing research, indicating that a community-led open BSFL system can generate valuable products while fostering circular economy principles with minimal financial, technological, energy and water resources.
Serotype distribution and antibiotic susceptibility of Streptococcus pneumoniae among healthy children in selected MOH areas in the Colombo district
Authors: Gonapaladeniya G. D. M. C. , Liyanage G. S. H. , Weerasekara M. M. , Jayakody S. N. , Wickramasekara M. H. M. , Dissanayake D. M. B. T.
Published: December 2023

NA
Monitoring coliform contamination at Mahaweli river water intakes to ensure safe drinking water supply
Authors: Thilakarathna P. T. A. , Fareed F. , Athukorala S. , Premachandra T. N. , Noordeen F. , Makehelwela M. , Fernando R. , Gamage C. , Rajapakse M. , Weragoda S. K. , Karunaratne S. H. P. P.
Published: December 2023

NA
A preliminary study on antibacterial activity of common antiseptic and herbal soaps in Sri Lanka against Staphylococcus aureus
Authors: Samaraweera G. A. , Perera M. T. S. M. , Opanayake P. M. , Wageesha N. D. A. , De Silva N. , Perera P. D. V. M.
Published: December 2023

NA
Co-occurrence of toxic epidermal necrolysis in a human immune deficiency virus infected person due to elthrombopag or ofloxacin – a rare occurrence
Authors: Chandraratne S.H. , Udagedara C. , Karunaratne Y.L.B. , Ekanayake C.
Published: December 2023

Toxic epidermal necrolysis (TEN), a severe drug reaction which is more commonly seen in human immune deficiency virus (HIV) infected persons. It occurs commonly with anti-retroviral treatment and sulfonamides. TEN is reported previously with ofloxacin. But there are no reported cases of elthrombopag induced TEN. Early identification and withdrawal of the culprit will enhance rapid recovery and less mortality. Reporting the noted medications vulnerable for TEN will help medical personal in identifying the drug reaction and causative.

We are reporting a 45 years old male with HIV infection developed TEN with elthrombopag and ofloxacin. We identified skin tenderness of erythematous maculopapular lesions as an early identification feature for TEN before appearing typical mucosal lesions, dusky red necrotic skin patches or nikolsky sign.
Acitretin and pityriasis rubra pilaris – can we challenge deranged liver?
Authors: Fernando W.K.B.A. , Dinupa K.D.T. , Dahanayake B.E.S. , Perera W.N.C.
Published: December 2023

Pityriasis Rubra Pilaris (PRP) is a rare chronic inflammatory papulosquamous disease. It has variable clinical presentations with six subgroups1. We describe a patient presented with PRP type 1 with altered liver functions and dyslipidemia successfully treated with acitretin. Acitretin is considered first-line therapy2, although it has relative contraindications in patients with altered liver functions and may result in dyslipidemia and liver damage as a complication. Vigilant use of acitretin may be beneficial in a resource-poor setting to treat PRP.
The Cyclin D3 Protein Enforces Monogenic TCRβ Expression by Mediating TCRβ Protein–Signaled Feedback Inhibition of Vβ Recombination
Authors: Culberson Erica J , Shields Kymberle C , Glynn Rebecca A , Allyn Brittney M , Hayer Katharina E , Bassing Craig H
Published: December 2023

In jawed vertebrates, adaptive immunity depends on the process of V(D)J recombination creating vast numbers of T and B lymphocytes that each expresses unique Ag receptors of uniform specificity. The asynchronous initiation of V-to-(D)J rearrangement between alleles and the resulting protein from one allele signaling feedback inhibition of V recombination on the other allele ensures homogeneous receptor specificity of individual cells. Upon productive Vβ-to-DβJβ rearrangements in noncycling double-negative thymocytes, TCRβ protein signals induction of the cyclin D3 protein to accelerate cell cycle entry, thereby driving proliferative expansion of developing αβ T cells. Through undetermined mechanisms, the inactivation of cyclin D3 in mice causes an increased frequency of αβ T cells that express TCRβ proteins from both alleles, producing lymphocytes of heterogeneous specificities. To determine how cyclin D3 enforces monogenic TCRβ expression, we used our mouse lines with enhanced rearrangement of specific Vβ segments due to replacement of their poor-quality recombination signal sequence (RSS) DNA elements with a better RSS. We show that cyclin D3 inactivation in these mice elevates the frequencies of αβ T cells that display proteins from RSS-augmented Vβ segments on both alleles. By assaying mature αβ T cells, we find that cyclin D3 deficiency increases the levels of Vβ rearrangements that occur within developing thymocytes. Our data demonstrate that a component of the cell cycle machinery mediates TCRβ protein–signaled feedback inhibition in thymocytes to achieve monogenic TCRβ expression and resulting uniform specificity of individual αβ T cells.
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies
Authors: Kammann Tobias , Gorin Jean-Baptiste , Parrot Tiphaine , Gao Yu , Ponzetta Andrea , Emgård Johanna , Maleki Kimia T , Sekine Takuya , Rivera-Ballesteros Olga ,   Karolinska COVID-19 Study Group, Gredmark-Russ Sara , Rooyackers Olav , Skagerberg Magdalena , Eriksson Lars I , Norrby-Teglund Anna , Mak Jeffrey Y W , Fairlie David P , Björkström Niklas K , Klingström Jonas , Ljunggren Hans-Gustaf , Aleman Soo , Buggert Marcus , Strålin Kristoffer , Sandberg Johan K
Published: December 2023

Mucosal-associated invariant T (MAIT) cells are an abundant population of unconventional T cells in humans and play important roles in immune defense against microbial infections. Severe COVID-19 is associated with strong activation of MAIT cells and loss of these cells from circulation. In the present study, we investigated the capacity of MAIT cells to recover after severe COVID-19. In longitudinal paired analysis, MAIT cells initially rebounded numerically and phenotypically in most patients at 4 mo postrelease from the hospital. However, the rebounding MAIT cells displayed signs of persistent activation with elevated expression of CD69, CD38, and HLA-DR. Although MAIT cell function was restored in many patients, a subgroup displayed a predominantly PD-1high functionally impaired MAIT cell pool. This profile was associated with poor expression of IFN-γ and granzyme B in response to IL-12 + L-18 and low levels of polyfunctionality. Unexpectedly, although the overall T cell counts recovered, normalization of the MAIT cell pool failed at 9-mo follow-up, with a clear decline in MAIT cell numbers and a further increase in PD-1 levels. Together, these results indicate an initial transient period of inconsistent recovery of MAIT cells that is not sustained and eventually fails. Persisting MAIT cell impairment in previously hospitalized patients with COVID-19 may have consequences for antimicrobial immunity and inflammation and could potentially contribute to post-COVID-19 health problems.
Treble or Trouble: Mental Health Experiences of Gender-Diverse Collegiate Marching Band Artists
Authors: Uriegas Nancy A. , Winkelmann Zachary K. , Emerson Dawn M. , Moore Kenya , Portillo Breanna , Torres-McGehee Toni M.
Published: December 2023

Context

For gender-diverse (GD) college marching band (MB) artists, the risks for anxiety and depression may be higher as they navigate the demands and stressors associated with MB, college, and their gender identity.

Objectives

To examine the risks of anxiety and depression across GD MB artists and to explore their barriers and attitudes toward seeking mental health (MH) care.

Design

Cross-sectional study.

Setting

Online survey.

Patients or Other Participants

Seventy-eight GD individuals (transgender = 12, nonbinary = 66, age = 19 ± 1 years).

Main Outcome Measure(s)

A survey was used to assess demographics, anxiety risk using the State-Trait Anxiety Inventory, depression risk using the Center for Epidemiologic Studies Depression Scale, and barriers and attitudes using the Barriers Towards Seeking Help Checklist, the Attitudes Toward Seeking Professional Psychological Help Scale-Short Form, and the Mental Help Seeking Attitudes Scale. We calculated descriptive statistics and univariate analyses to evaluate scores, risks, and differences between MH and receiving assistance.

Results

Participants had high state anxiety (mean = 52.0 ± 112.1), trait anxiety (mean = 55.2 ± 10.0), and symptoms of depression (mean = 30.4 ± 12.0) based on the State-Trait Anxiety Inventory and the Center for Epidemiologic Studies Depression Scale. Overall, 78.2% (n = 61 of 78) of GD MB artists were considered at risk for both state and trait anxiety and depression, and 18% (n = 11 of 61) did not seek help from an MH professional. These GD MB artists cited a lack of time (82.1%; n = 64 of 78) as the primary barrier to seeking professional help. The mean score on the Attitudes Toward Seeking Professional Psychological Help Scale-Short Form for all GD artists was 19.5 ± 5.0, and the total score for the Mental Help Seeking Attitudes Scale was 47.8 ± 9.2, which indicated more favorable attitudes toward seeking professional help.

Conclusions

We identified high rates of clinical symptoms for depression and anxiety among GD MB artists. The data are consistent with those from other minority populations and above the normative values for cisgender students. The lack of help-seeking behaviors in nearly 15% of at-risk participants highlights the need for specialized resources for GD patients and those participating in MB.
Recent Advances in Lung Isolation Devices and Techniques
Authors: Parab Swapnil Y , Majety Sarat Chandra , Singhal Sanjoli
Published: December 2023

The advancements in thoracic surgery have been complemented by innovations in lung isolation devices and techniques. The traditional double-lumen tube (DLT) has undergone modifications to reduce the dependence on flexible bronchoscope (e.g. VivaSight™ DLT) or to increase its adaptability in the deviated tracheobronchial tree (e.g. Silbroncho® DLT). Newer DLTs, like ECOM DLT, also helps in monitoring the cardiac output, whereas Ventibronc Anchor DLT reduces the chances of misplacements. Newer bronchial blockers like EZ blocker® have a unique design to facilitate its placement and ability to conduct alternate lung isolation. Lately, non-intubated video-assisted thoracoscopic surgeries have shown promising results in reducing airway trauma and postoperative morbidity. Despite these advances, the cost and availability of devices become the limiting factor for their widespread use. This narrative review describes the features of the newer lung isolation devices and presents the available evidence regarding their application in the field of thoracic anaesthesia.
Oncofertility: technical challenges in immature testicular tissue banking
Authors: Tholeti Prathima
Published: December 2023

The gonadotoxicity of cancer therapy ranges from severe to mild effects on spermatogenesis, structural, functional, and genetic integrity of spermatozoa. However, these effects are even more pronounced in prepubertal males due to the susceptibility of the prepubertal testis to cytotoxic therapy. The proliferating germ cells in the prepubertal testis are mitotic in nature, thereby becoming a target for anticancer agents. Immature testicular tissue (ITT) cryopreservation is offered as the only fertility preservation (FP) strategy for prepubertal males facing gonadotoxic risk, though it is still experimental in nature. Multiple cryopreservation protocols have been developed to ensure safe and efficacious storage of the tissue and to enable maximum recovery of germ cells during thawing. The thawed tissue can then be used for fertility restoration by either in vitro spermatogenesis or transplantation to reinitiate spermatogenesis and thereby result in the production of mature spermatozoa. However, there are many challenges to overcome to successfully offer this procedure as an established one. This mini-review gives an overview of the progress in ITT cryopreservation and fertility restoration procedures, along with the other challenges.
Dynamics of HOXA10 expression in ectopic endometrium of a mouse model of endometriosis
Authors: Mishra Anuradha , Modi Deepak
Published: December 2023

Introduction: Homeobox gene A10 (HOXA10) is a transcription factor that plays a key role in maintaining endometrial homeostasis. In women with endometriosis, HOXA10 expression is downregulated, which is thought to cause progesterone resistance. However, it is unknown whether this downregulation is a cause or consequence of endometriosis. Materials and Methods: In this study, we used a mouse model of endometriosis and demonstrated that compared to the normal endometrium, the expression of HOXA10 is progressively downregulated during lesion development (from day 10 to day 65). Results: We observed that the expression of HOXA10 is lower in both well-differentiated and mixed types of endometriosis. During lesion development, the levels of HOXA10 were initially downregulated in epithelial cells more than in stromal cells. However, as the lesion development progressed further, the stromal expression was drastically reduced. While the nucleocytoplasmic ratio of HOXA10 was identical between control and endometriosis lesions at the initial stages, at later time points, HOXA10 remained largely nuclear, with little expression in the stroma. Conclusion: We conclude that the downregulation of HOXA10 is a consequence of endometriosis and may contribute toward its pathogenesis.
Oral Health Status and Dental Treatment Needs among Children with and without Hearing Impairment in Hyderabad, India: A Cross-sectional Study
Authors: Koneti Laxmi Ramitha , Anitha C. T.
Published: December 2023

Aim:

The study aimed to assess the oral health status and dental treatment needs of children with hearing impairment (CHI) and children without hearing impairment (HI).

Materials and Methods:

A cross-sectional study was conducted among 110 CHI and 105 children without HI (13–18 years) in Hyderabad, India from February–March 2019. Two special schools (for CHI) and one government (regular) school were selected by purposive sampling. American Dental Association Type-4 dental examination was conducted at respective school premises and modified World Health Organization Oral Health Assessment form, 2013 was used to record the oral health findings. Chi-square test/Fisher’s exact test and Z-test were calculated at P < 0.05.

Results:

Prevalence of dental caries was 69% and 26% among CHI and children without HI, respectively (P < 0.001). Good oral hygiene, as determined by oral hygiene index scores, was merely 31.8% among CHI compared to 82.9% in children without HI. CHI in need of any dental treatment was higher at 89.1% compared to 43.8% of children without HI.

Conclusion:

The present study demonstrates that CHI has a higher prevalence of dental caries than children without HI in Hyderabad, India. This high prevalence of caries among CHI represents the unmet dental needs and neglect of their oral health care. Oral health promotion is the need of the hour to help nurture good oral health practices among children in general and CHI in particular.