bluuebunny/crossref_metadata_2025 huggingface dataset:
Decentring European Union Foreign Policy: Addressing Colonial Dynamics in EU‐Algeria Relations
Authors: Barbieux Francois , Bouris Dimitris
Published: September 2024

The presence of eurocentrism in the European Union's (EU) foreign policy towards the Middle East and North Africa (MENA) reproduces colonial dynamics that undermine the pragmatic and ethical relevance of the EU as an international actor. This article questions eurocentric assumptions underpinning the EU's foreign policy towards the MENA, specifically analysing the case of Algeria. It proposes an innovative conceptual framework drawing on the decentring literature as well as post‐structuralist insights from Cebeci's work. When analysed in politico‐cultural, socio‐economic and security terms, EU‐Algeria relations reflect spatial, normative, polity and disciplinary Eurocentricity, which becomes manifest in the hierarchical, asymmetrical and securitised nature of this relationship. These findings contribute to the decentring turn in the literature by attempting to put the ‘foreign’ back into the study and practice of foreign policy, recognising colonial linearity and addressing its enduring avatars.
Simulating the Relationship Between Nonword Repetition Performance and Vocabulary Growth in 2‐Year‐Olds: Evidence From the Language 0–5 Project
Authors: Rowland Caroline F. , Bidgood Amy , Jones Gary , Jessop Andrew , Stinson Paula , Pine Julian M. , Durrant Samantha , Peter Michelle S.
Published: September 2024

A strong predictor of children's language is performance on non‐word repetition (NWR) tasks. However, the basis of this relationship remains unknown. Some suggest that NWR tasks measure phonological working memory, which then affects language growth. Others argue that children's knowledge of language/language experience affects NWR performance. A complicating factor is that most studies focus on school‐aged children, who have already mastered key language skills. Here, we present a new NWR task for English‐learning 2‐year‐olds, use it to assess the effect of NWR performance on concurrent and later vocabulary development, and compare the children's performance with that of an experience‐based computational model (CLASSIC). The new NWR task produced reliable results; replicating wordlikeness effects, word‐length effects, and the relationship with concurrent and later language ability we see in older children. The model also simulated all effects, suggesting that the relationship between vocabulary and NWR performance can be explained by language experience‐/knowledge‐based theories.
Dissecting Cellulitis and Alopecic and Aseptic Nodules of the Scalp in Pediatric Patients: An Atypical Age of Presentation Observed in Two Cases
Authors: Lima‐Galindo Anabell Andrea , Garza‐García Leslie Monserrat , Olvera‐Rodríguez Valeria , Favela‐Galvez Miguel Bonifacio , Ocampo‐Candiani Jorge , Alba‐Rojas Erika
Published: September 2024

Dissecting cellulitis of the scalp (DCS) is a rare inflammatory condition that progresses from papules and pustules to nodules and abscesses, ultimately leading to cicatricial alopecia. It primarily affects African men between the ages of 15 and 62, with exceptionally low prevalence in children. A milder form, described as “alopecic and aseptic nodules of the scalp” (AANS), presents as aseptic nodules associated with non‐scarring alopecia and has a good prognosis. We report two atypical cases of DCS in Hispanic pediatric patients: an 18‐month‐old female infant and an 11‐year‐old male child who had a rapid and favorable clinical resolution consistent with AANS.
Impact sculpting of the early martian atmosphere
Authors: Shorttle Oliver , Saeidfirozeh Homa , Rimmer Paul Brandon , Laitl Vojtĕch , Kubelík Petr , Petera Lukáš , Ferus Martin
Published: September 2024

Intense bombardment of solar system planets in the immediate aftermath of protoplanetary disk dissipation has played a key role in their atmospheric evolution. During this epoch, energetic collisions will have removed substantial masses of gas from rocky planet atmospheres. Noble gases are powerful tracers of this early atmospheric history, xenon in particular, which on Mars and Earth shows significant depletions and isotopic fractionations relative to the lighter noble gasses. To evaluate the effect of impacts on the loss and fractionation of xenon, we measure its ionization and recombination efficiency by laser shock and apply these constraints to model impact-driven atmospheric escape on Mars. We demonstrate that impact bombardment within the first 200 to 300 million years of solar system history generates the observed Xe depletion and isotope fractionation of the modern martian atmosphere. This process may also explain the Xe depletion recorded in Earth’s deep mantle and provides a latest date for the timing of giant planet instability.
Boosting the photocatalytic decontamination efficiency using a supramolecular photoenzyme ensemble
Authors: Jiang Ruifen , Luo Gan , Chen Guosheng , Lin Yuhong , Tong Linjing , Huang Anlian , Zheng Yang , Shen Yong , Huang Siming , Ouyang Gangfeng
Published: September 2024

Continuous industrialization has raised daunting environmental concerns, and there is an urgent need to develop a sustainable strategy to tackle the contamination issues. Here, we report a supramolecular photoenzyme ensemble enabling the harvest of solar energy to remove contaminations in water. The well-sourced oxidoreductase, laccase, is confined into a photoactive hydrogen-bonded organic framework (PHOF) through an in situ encapsulation method. The direct electron migration between the oxidation center in a PHOF and the reduction center in laccase facilitates synergistic photoenzyme-coupled catalysis, showing two orders of magnitude higher activity than free laccase for pollutant degradation under visible light, without the need for sacrificial agents or costly co-mediators. Such high decontamination efficiency also surpasses the reported catalysts. The structure and decontamination function of this supramolecular photoenzyme ensemble remain highly stable in complex environment matrices, presenting desirable reusability and almost 100% conversion efficiency of pollutants for real sewage samples. Our conceptual photoenzyme hybrid catalyst offers important insights into green and sustainable water decontamination.
Chemically programmed metabolism drives a superior cell fitness for cartilage regeneration
Authors: Chen Yishan , Yan Yiyang , Tian Ruonan , Sheng Zixuan , Li Liming , Chen Jiachen , Liao Yuan , Wen Ya , Lu Junting , Liu Xinyu , Sun Wei , Wu Haoyu , Liao Youguo , Zhang Xianzhu , Chen Xuri , An Chengrui , Zhao Kun , Liu Wanlu , Gao Jianqing , Hay David C. , Ouyang Hongwei
Published: September 2024

The rapid advancement of cell therapies underscores the importance of understanding fundamental cellular attributes. Among these, cell fitness—how transplanted cells adapt to new microenvironments and maintain functional stability in vivo—is crucial. This study identifies a chemical compound, FPH2, that enhances the fitness of human chondrocytes and the repair of articular cartilage, which is typically nonregenerative. Through drug screening, FPH2 was shown to broadly improve cell performance, especially in maintaining chondrocyte phenotype and enhancing migration. Single-cell transcriptomics indicated that FPH2 induced a super-fit cell state. The mechanism primarily involves the inhibition of carnitine palmitoyl transferase I and the optimization of metabolic homeostasis. In animal models, FPH2-treated human chondrocytes substantially improved cartilage regeneration, demonstrating well-integrated tissue interfaces in rats. In addition, an acellular FPH2-loaded hydrogel proved effective in preventing the onset of osteoarthritis. This research provides a viable and safe method to enhance chondrocyte fitness, offering insights into the self-regulatory mechanisms of cell fitness.
Voltage-dependent G-protein regulation of Ca
V
2.2 (N-type) channels
Authors: Nilsson Michelle , Wang Kaiqian , Mínguez-Viñas Teresa , Angelini Marina , Berglund Stina , Olcese Riccardo , Pantazis Antonios
Published: September 2024

How G proteins inhibit N-type, voltage-gated, calcium-selective channels (Ca
V
2.2) during presynaptic inhibition is a decades-old question. G proteins Gβγ bind to intracellular Ca
V
2.2 regions, but the inhibition is voltage dependent. Using the hybrid electrophysiological and optical approach voltage-clamp fluorometry, we show that Gβγ acts by selectively inhibiting a subset of the four different Ca
V
2.2 voltage-sensor domains (VSDs I to IV). During regular “willing” gating, VSD-I and -IV activations resemble pore opening, VSD III activation is hyperpolarized, and VSD II appears unresponsive to depolarization. In the presence of Gβγ, Ca
V
2.2 gating is “reluctant”: pore opening and VSD I activation are strongly and proportionally inhibited, VSD IV is modestly inhibited, while VSD III is not. We propose that Gβγ inhibition of VSDs I and IV underlies reluctant Ca
V
2.2 gating and subsequent presynaptic inhibition.
Triple oxygen isotope reveals insolation-forced tropical moisture cycles
Authors: Sha Lijuan , Dang Haowen , Wang Yue , Wassenburg Jasper A. , Baker Jonathan L. , Li Hanying , Sinha Ashish , Ait Brahim Yassine , Wu Nanping , Lu Zhengyao , Yang Ce , Dong Xiyu , Lu Jiayu , Zhang Haiwei , Mahata Sasadhar , Cai Yanjun , Jian Zhimin , Cheng Hai
Published: September 2024

Tropical oceans are the main global water vapor and latent heat sources, but their responses to radiative forcing remain unclear. Here, we investigate oceanic moisture dynamics of the western tropical Pacific (WTP) over the past 210,000 years through an approach of planktonic foraminiferal triple oxygen isotope (Δ′
17
O). The Δ′
17
O record is dominated by the precession cycles (~23,000 years), with lower values reflecting higher humidity in concert with higher Northern Hemisphere summer insolation. Our empirical and modeling results, combined with other geological archives, suggest that the enhanced moisture convergence over the WTP largely intensifies changes in the meridional and zonal hydrological cycles, affecting rainfall patterns in East Asia and northern South America. We propose that the insolation-driven WTP moisture dynamics play a pivotal role in regulating tropical hydroclimate.
Herpes zoster as the initial manifestation of varicella-zoster virus infection in a healthy toddler
Authors: Hamed Fatma N , Bates Rhiannon A , Oikonomou Stamatios
Published: September 2024

Herpes zoster (HZ), commonly known as shingles, is a painful blistering rash in dermatomal distribution, caused by the reactivation of varicella-zoster virus (VZV) that was acquired during a primary varicella infection. While commonly afflicting adults, cases of HZ in paediatric patients are infrequently reported. Such cases are predominantly reported in children who have had prior exposure to VZV, either during pregnancy, early childhood or have been vaccinated with live attenuated VZV. This report presents the first known case to our knowledge of HZ as the initial manifestation of a VZV infection in an immunocompetent toddler in the UK. The report details the chronology of the infection event and discusses the clinical context behind HZ presentations in paediatrics globally. It provides a compelling illustration of the uncommon presentation of VZV infection in an immunocompetent child devoid of antecedent virus exposure, thus meriting acknowledgement and potentially further investigation as to the cause.
PhD Thesis: Evolutionary Computation Methods for Instance Generation in Optimisation Domains
Authors: Marrero Alejandro
Published: September 2024

The generation of instances of optimisation problems is a very common task in Computer Science. Traditionally, researchers apply statistical or pseudo-random methods to create instances used to validate their proposals: algorithms or operators. At the same time, some authors have proposed sets known as benchmarks so that new proposals can be evaluated in these instances, thus avoiding the task of generating instances. However, these sets are often characterised by (1) being designed to be hard to solve by off-the-shelf, state-of-the-art algorithms at the time of their creation and (2) by their low diversity, meaning the instances tend to share many similar characteristics.
Early Adipogenesis and Upregulation of UCP1 in Mesenchymal Stromal Cells Stimulated by Devitalized Microfragmented Fat (MiFAT)
Authors: Coccè Valentina , Missaglia Sara , Martegani Eleonora , Tavian Daniela , Doneda Luisa , Manfredi Barbara , Alessandri Giulio , Corradini Costantino , Giannì Aldo , Ciusani Emilio , Paino Francesca , Pessina Augusto
Published: September 2024

Adipose tissue is mainly composed by adipocytes. Moreover, mesenchymal stromal/stem cells (MSCs), macrophages, endothelial cells, and extracellular matrix components are present. The variety of molecules as cytokines and growth factors of its structure very rich in blood vessel makes it also similar to a true endocrine organ that however needs still to be fully investigated. In our study, we used human lipoaspirate to obtain mechanically microfragmented fat (MiFAT) which was washed and then devitalized by freezing–thawing cycles. In our experiments, thawed MiFAT was used to stimulate cultures of MSCs from two different sources (adipose tissue and gingiva papilla) in comparison with a traditional stimulation in vitro obtained by culturing MSCs with adipogenic medium. MSCs stimulated with MiFAT showed a very early production of lipid droplets, after only 3 days, that correlated with an increased expression of adipokines. Furthermore, a significant upregulation of PPAR gamma 1 alpha coactivator (PPARGC1A) was observed with an overexpression of uncoupling protein 1 (UCP1) that suggest a pattern of differentiation compatible with the beige–brown fat.
Silver Nanoparticles Based on Annona muricata Peel Reduce Cell Viability in Medulloblastoma and Neuroblastoma Cell Lines
Authors: Lira-Díaz Eduardo , Cruz-Márquez Ricardo , González-Pedroza María Guadalupe , Gonzalez-Perez Oscar , Morales-Luckie Raúl Alberto , Acevedo-Fernández Juan José
Published: September 2024

Silver nanoparticles (AgNPs) can be obtained from plants and other organisms through green synthesis methods, considered eco‐friendly and highly biocompatible. In this way, using plants with antitumor bioactive compounds increases cytotoxicity against tumor cells, acting in synergy between plant bioactive compounds (covering the nanoparticle) and AgNPs by itself. Acetogenins are the signature bioactive compounds present in Annona muricata (soursop) that induce tumor cell death by blocking respiratory complex 1 of the electron transport chain of the mitochondria, which is overexpressed in high‐grade tumors such as medulloblastoma, a high‐grade tumor of embryonic origin that affects the pediatric population. In this study, we evaluated the effects of AgNPs derived from an aqueous extract of soursop peel on neuroblastoma (CHP‐212) and medulloblastoma (Daoy and D341 Med) cell lines. Additionally, we evaluated the viability of fibroblasts (HDFn) and macrophages (RAW 264.7) to observe biosafety in nontumor cells. Our results showed that AgNPs in soursop peel reduced the viability of CHP‐212, Daoy, and D341 Med cell lines, in contrast to the fibroblast cell line. Thus, AgNPs derived from the aqueous extract of soursop peel may serve as a promising therapeutic tool for treating brain tumors.
Genome‐Wide Characterization and Analysis of the SPL Gene Family in Eucalyptus grandis
Authors: An Lijun , Ma Jiasi , Fan Chunjie , Li Huiling , Wu Aimin
Published: September 2024

SQUAMOSA promoter‐binding protein‐like (SPL) gene family, a group of plant‐specific transcription factors, played crucial roles in regulating plant growth, development, signal transduction, and stress response. This study focuses on the SPL gene family in the fast‐growing Eucalyptus grandis, employing bioinformatics approaches to identify and analyze the gene physiochemical characteristics, conserved domains, structural composition, chromosomal distribution, phylogenetic relationships, cis‐acting elements, and their expression patterns in various tissues and stress treatments. Twenty‐three SPL genes were identified in E. grandis, which uneven distributed across seven chromosomes and classified into five groups. Prediction of cis‐acting elements revealed that these genes might be related to light, hormone, and stress responses. Furthermore, EgSPL9 and EgSPL23, mainly expressed in the stem apex and lateral branches, seem to be involved in hormone stress resistance. Our study provides insights into the potential functions of the EgSPL genes in plant growth, stress response, and hormone transduction, offering valuable perspectives for subsequent research into their biological roles.
Relationship of Mitochondrial DNA Oxidation and Content with Metabolic Syndrome and Cardiovascular Risk in Obesity Phenotypes
Authors: Rojo Mailén , Pérez Hernán , Millán Andrea Liliana , Pautasso María Constanza , Frechtel Gustavo Daniel , Cerrone Gloria Edith
Published: September 2024

Objective. Obesity, chronic inflammation, and oxidative stress can influence mitochondrial DNA (mtDNA) content. Our objective was to evaluate the oxidation level and content of mtDNA and its relationship with metabolic parameters in metabolically healthy obese (MHO) compared to metabolically unhealthy obese (MUO) and normal weight (NW) controls. Materials and Methods. We studied 94 NW, 95 MHO, and 97 MUO individuals between 18 and 80 years old. Relative mtDNA content and mtDNA oxidation level (8‐oxoguanine, 8‐OxoG) were determined in peripheral blood leukocytes by the SYBR Green method of real‐time PCR. One‐way ANOVA and Tukey test were used to compare biochemical, clinical, and anthropometric characteristics, as well as mtDNA content and 8‐OxoG. Results. A progressive decrease in mtDNA content was observed between NW, MHO, and MUO with significant differences in MUO vs. NW (p: 0.04). An increase in 8‐OxoG was observed in MUO patients compared to the other groups (MUO vs. MHO p: 0.01; MUO vs. NW p: 0.04). mtDNA content was directly correlated with HDL‐c (p < 0.01) and inversely with waist circumference (p: 0.01) and LDL‐c (p: 0.05). mtDNA content decreased, and the oxidation level increased concomitantly with the presence of obesity, the number of MS components, higher coronary risk, and insulin resistance parameters. Conclusion. MHO presented a similar mtDNA oxidation level to NW and mtDNA content to the MUO, placing the MHO individuals as having an intermediate phenotype. Changes in mtDNA content and oxidation were correlated to the lipid profile related to obesity and/or MS presence, probably associated with oxidative stress and chronic low‐grade inflammation.
Study on the Application of a Photocatalytic Titanium Dioxide Coating on Glass Beads for the Treatment of Perfluorooctane Sulfonic Acid
Authors: Nam Dao Duy , Hong Hanh Cao Thi , Huyen Nghiem Minh , Van Dieu-Anh , Hung Ha Vinh , Trang Vu Minh , Minh Vu Quang , Ngoc Nguyen Bich , Thu Ha Vu Thi , Hai Huynh Trung
Published: September 2024

Perfluorooctanesulfonic (PFOS) acid is a persistent anthropogenic organic fluorinated compound ubiquitous in industrial applications and is resistant to conventional wastewater treatment methods. Human exposure to PFOS can cause adverse health effects. In this study, a low‐content titanium dioxide (TiO2) photocatalyst coated on glass beads was synthesized through a simple method and showed improved activity and durability. This material exhibited easy recovery and potential for large‐scale applications. The efficacy of the TiO2 nanoparticle‐deposited glass beads’ (TiO2@GBs) photocatalyst in treating PFOS contaminants in wastewater was explored, demonstrating its ability to promote photocatalytic reactions to break down PFOS into shorter chain byproducts. The study employed the response surface method (RSM) using the Box–Behnken design (BBD) to optimize treatment conditions at a PFOS concentration of 0.1 mg/L. Investigated factors included pH (4–9), TiO2 dosage (0.11–0.53 g/L), and irradiation time (4–8 h). Design‐Expert 12 software was used to plan and optimize the experiments. Fifteen experiments were conducted, and triplicate runs occurred at the center points of the experimental plan. ANOVA and Fisher’s test yielded an F value of 73.88 (p < 0.0001) which demonstrated the model’s statistical significance with over 99% confidence regression prediction. The optimized treatment conditions that achieved 100% degradation of PFOS included a pH of 4.55, TiO2 dosage of 0.396 mg/L, and irradiation time of 6.59 hours. After the photocatalytic treatment, PFOS was transformed into intermediate products such as PFPeA, PFHpA, L‐PFBS, and L‐PFHxS.
Metabolic Profiling and Early Diagnosis of Alcoholic Fatty Liver Disease Using Support Vector Machine Model
Authors: You Minjie , Zheng Fangfang , Zhou Tao , Xu Yanwen , Wu Jiaying , Zhuo Siyu , Shen Xiuwei , Hu Lufeng
Published: September 2024

Alcoholic fatty liver disease (AFLD) is one of the most common pathological changes associated with alcoholic liver disease. This study is aimed at investigating the specific metabolic changes occurring in AFLD and to develop a diagnostic method based on the blood metabolomics of AFLD. Twenty‐four rats were randomly divided into an AFLD group and a control group. The AFLD model was established by administering 40% alcohol and verified by pathologic examination. Metabolic changes in the blood were investigated by GC‐MS, and both hepatic function and metabolic ability were assessed. Using the metabolic data, a diagnostic model was developed with a support vector machine (SVM). The model was validated using cross‐validation techniques and achieved a classification accuracy of 100%. Additionally, there were statistically significant differences in metabolic, hepatic function, and pharmacokinetic changes between the two groups. The level of urea, hydroxysuccinic acid, 2‐propenoic acid, total cholesterol, and high‐density lipoprotein cholesterol increased, area under the concentration‐time curve (AUC) (0 − t), AUC (0 − ∞), and Cmax of phenacetin shorten in the AFLD group (p < 0.05). The classification accuracy of the SVM model based on metabolic data was 100%. In conclusion, the metabolic ability was heightened in the early stage of AFLD, leading to accelerated metabolism of urea and hydroxysuccinic acid. The SVM model can be used to detect early changes in AFLD based on metabolic data.
Pulp Sensitivity Testing in Multiple Sclerosis: Disease Duration and Sensory/Motor Associations—A Cross‐Sectional Study
Authors: Owlia Fatemeh , Noori Fereshteh , Zarchi Marzieh Abutorabi , Kazemipoor Maryam
Published: September 2024

Introduction: This study explores a relatively unexplored aspect of multiple sclerosis (MS) by examining the sensitivity threshold of dental pulp as a potential indicator of neuropathy in MS patients. Building upon earlier research that focused on assessing the response to electrical pulp testing in MS patients who did not have a history of trigeminal neuralgia, this survey is aimed at delving into the relationship between MS duration and the threshold for stimulation in response to pulp sensitivity tests.

Materials and Methods: This study encompassed a total of 124 maxillary central incisors from patients diagnosed with relapsing‐remitting multiple sclerosis (RRMS). The participants were uniform in terms of age, falling within the 18–50 years range, and all had RRMS with no history of trigeminal neuralgia. The electric pulp sensitivity test was conducted on all samples, and the results of the electric pulp testing (EPT) were recorded according to the grade of the pulp tester that elicited a response. The threshold was considered reached when the patient first experienced a burning sensation after EPT application and the use of 1,1,1,2‐tetrafluoroethane spray. Data analysis employed paired t‐tests, Fisher’s exact test, and Spearman correlation, with a significance level set at p < 0.05.

Results: Based on the study’s findings, the average response value to EPT was 2.69 ± 1.17, while the response time to the cold test was 2.61 ± 1.03 s. There was no statistically significant difference in the response to the cold test based on age (p = 0.45). However, it was observed that the mean response time to the cold test was significantly longer among male participants (p = 0.001). No significant differences were identified in the pulpal response to EPT or the cold test between patients with and without sensory‐motor involvement (p > 0.05). Furthermore, Spearman’s analysis revealed a noteworthy positive correlation between the electrical pulp threshold and the time taken to respond to the cold test (p = 0.025, r = 0.2).

Conclusions: The utilization of the pulpal sensitivity test in MS patients holds promise for practical clinical use. Notably, individuals with a more extended duration of the disease exhibited a notably elevated threshold for both the EPT and the cold test conducted on their maxillary central incisors.
Edema of the Scrotum and Penile Shaft: An Uncommon Initial Presentation of Acquired Angioedema With Low C1‐Inhibitor
Authors: Matheny Meghan V. , Craig Timothy , Clark Joseph Y.
Published: September 2024

Acquired angioedema with low C1‐inhibitor (AAE‐C1‐INH) is a rare disorder characterized by an acquired deficiency in the C1 esterase inhibitor (C1‐INH). This case report describes a 79‐year‐old patient presenting to the emergency department for painless swelling of his scrotum, penile shaft, and left lower and upper extremities with lab values consistent with acquired angioedema without identifiable lymphoreticular or rheumatic disorder on history, exam, or total body PET scan. Proper diagnosis of AAE‐C1‐INH is essential to prevent life‐threatening airway compromise, ensure proper therapy, and exclude lymphoreticular disorders as the etiology of AAE‐C1‐INH.
Figure S2 from A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples
Authors: Arakawa Yasuhiro , Elloumi Fathi , Varma Sudhir , Khandagale Prashant , Jo Ukhyun , Kumar Suresh , Roper Nitin , Reinhold William C. , Robey Robert W. , Takebe Naoko , Gottesman Michael M. , Thomas Craig J. , Boeva Valentina , Berruti Alfredo , Abate Andrea , Tamburello Mariangela , Sigala Sandra , Hantel Constanze , Weigand Isabel , Wierman Margaret E. , Kiseljak-Vassiliades Katja , Del Rivero Jaydira , Pommier Yves
Published: September 2024

Supplement Figure 2 related to Figure 4
As origens do Superman na Era de Prata e na Era de Bronze: uma análise semiótica
Authors: Bressan Adriano Braga , Gomes Nataniel dos Santos
Published: September 2024

Propõe que sejam demonstradas e comparadas duas fases do precursor das histórias de superaventura, o Superman. Para tanto, foram retomados os contextos de produção da chamada Era de Prata e a Era de Bronze dos quadrinhos, que passaram por diferentes autores, responsáveis por tornar o herói tanto vendável quanto significativo à época. Detalhes editoriais, escolhas narrativas e alguns fatos que contribuíram no plano discursivo foram abordados, a exemplo do Comics Code Authority, uma tentativa de censura que fez com que tudo o que era conhecido no universo dos super-heróis fosse modificado. Para realizar esta análise, foi utilizado o método abdutivo desenvolvido por Charles Sanders Peirce (1839-1914), o qual, por meio da união entre semiótica e comunicação, permitiu que fosse abordada a forma como o Superman, inserido nas mudanças de era, deixava de significar-se, gerando um estado de dúvida, para posteriormente reassumir sua imagem e inserir-se como o próprio herói. Sob a terminologia do aspecto triádico do autor, nos ativemos à análise das cores do uniforme do herói na tentativa de elucidar ao leitor sobre o quanto a sua existência, quando reunidas, superam aquilo que é posto em dúvida nos saltos cronológicos dos roteiros do personagem. Dessa forma, firmamos saber quem é o Superman, independentemente da época, de sua silhueta e de sua personalidade.
Nem hardware, nem software: o olhar voltado para o peopleware segundo o pensamento sistêmico e a comunicação organizacional
Authors: Barboza Odila de Fátima Passos , Dias Robson , Gomes Victor Márcio Laus Reis , Martinez Maria Cecília Alves , Curvello João José de Azevedo
Published: September 2024

O artigo estuda os processos comunicacionais e a dimensão humana em uma equipe de Tecnologia da Informação, a partir do pensamento sistêmico em Luhmann (2011), que enfatiza as interações como formas de comunicação. A partir da noção de peopleware, posicionamos quatro funções dos profissionais de informática conjugando-as com funções comunicacionais, em que: (1) o gestor operacional define o sentido (regras do negócio); (2) o gestor técnico faz a supervisão da demanda com (3) o analista de sistemas e de desenvolvimento da fábrica de software; e também a supervisão com  (4) o analista de suporte sobre as condições de hardware . Nesse sentido, o objetivo é o de interpretar processos comunicacionais e relações sistêmicas nos papéis funcionais de equipes de TI, ofertando essa leitura às áreas de Comunicação Organizacional e de Informática e trazendo uma discussão pouco usual nesse meandro: a da dimensão humana, comunicacional e sistêmica.
O envelhecimento na tela: o discurso da velhice ativa em programas de TV e documentários
Authors: Dantas Sílvia Góis
Published: September 2024

This article aimed to analyze the discourse on old age based on four objects: (I) series of special reports on aging on Jornal Nacional (TV Globo, 2017); (II) report shown on the program Mais Você (TV Globo, 2016); (III) documentary series Muitos anos de vida (Alberto Renault, GNT, 2016) and (IV) documentary Envelhescência (Gabriel Martinez, 2015). Based on the premise of Guita Grin Debert that old age is a social construction and based on the studies on population aging and demographic transition in Brazil, we found that the discourse on aging in different media products is strongly linked to the attributes of youth, activity and the obligation of happiness, as a mark of contemporaneity.
A questão social como investimento: empresas e políticas sociais no Brasil
Authors: Tommasi Livia de
Published: September 2024

O objetivo do texto é propor uma chave de leitura para indagar a atuação do setor empresarial no âmbito das políticas sociais. Quais foram as condições de possibilidade para a afirmação do protagonismo do empresariado na gestão da pobreza? Como o enfrentamento da questão social via investimentos sociais lucrativos tem se legitimado no país? Os argumentos expostos, de caráter exploratório, articulam uma bibliografia dispersa com o intuito de despertar o interesse por questões pouco exploradas no âmbito da pesquisa em ciências sociais.
Uma gênese da literatura contemporânea para crianças e jovens: o realismo na literatura juvenil, de Lenice Bueno
Authors: Pires Carlos
Published: September 2024

O texto apresenta o livro O realismo na literatura juvenil: Odette de Barros Mott e a denúncia social,de Lenice Bueno, atento à elaboração que a pesquisadora realiza na identificação e articulação das principais linhas de força da literatura contemporânea para crianças e jovens no Brasil.
Mask-related acne during the Covid-19 pandemic
Authors: Santos Vitorino Modesto dos , Sugai Kin Modesto
Published: September 2024

The lessons from the recent pandemic should be given due consideration and used as fundamental tools to conduct new research aimed at minimizing the major adverse effects of inappropriate use of standard protective measures by patients and healthcare professionals. This manuscript specifically addresses the first occurrence or worsening of acne associated with daily use of facial masks for very prolonged periods. The authors of the additional comments on the latest literature data hope to highlight timely topics on "mask acne" published in the latest edition of this Journal.
Apresentação
Authors: Iazzetta Fernando
Published: September 2024

Neste volume especial estão reunidos alguns trabalhos de importantes especialistas das áreas de música e filosofia, tanto do Brasil como do exterior, bem como os resultados de pesquisas realizadas por alunos de pós-graduação, como exemplos de como se dão as relações entre as duas áreas. Ao mesmo tempo, pretende-se prestar uma merecida homenagem ao Professor Paulo Justi, falecido em 2010. Fagotista de formação, responsável pela educação de várias gerações de instrumentistas na UNICAMP, ele era um grande defensor da aproximação das artes com a filosofia no âmbito da universidade. Tendo terminado seu doutorado em filosofia em 2009 no IFCH-UNICAMP, com o tema “Kant e a música na Crítica da Faculdade do Juízo”, não teve tempo de ver seus sonhos realizados. Esperamos que os trabalhos aqui reunidos possam demonstrar um pouco da variedade das pesquisas que vêm sendo realizadas na área, de modo a estimular os jovens pesquisadores a explorar as profícuas relações entre música e filosofia.
Bancas e famílias do RAP Nacional: espaço vivo de convivência e afeto entre masculinidades negras
Authors: Santana Junior José Balbino
Published: September 2024

As bancas e famílias são representações de coletivos onde a presença de homens negros é majoritária e, pensando na música também como um espaço de resistência e representatividade, são um dos poucos espaços onde uma reunião de homens negros pode prosperar e se transformar em transmissão de cultura, conhecimento e afeto. Enxergando o movimento Hip Hop e suas formas de organização através de uma lente decolonial o artigo busca entender histórico e socialmente estes fenômenos considerando a música como liga principal de uma cadeia de distribuição de saberes e cuidados. Constatando a brutalidade do Estado brasileiro diante da comunidade negra e mais violenta e especificamente por sobre os homens negros, esta escrita pretende pensar a música RAP e as organizações que dela frutificam como espaços onde estas vidas são possíveis e podem se relacionar. O gatilho desta empreitada é uma apresentação do Rapper Daganja e a Família Ugangue, ocorrida em formato de Live Streaming, durante a pandemia do COVID-19.
Tankuang and His Work in Tibetan Translation: Revisiting IOL Tib J 26 and the Mahādeva Narrative
Authors: Li Channa
Published: September 2024

The Tibetan manuscript IOL Tib J 26 claims to contain a version of the Mahādeva narrative based on a Chinese source. In this paper, I identify this Chinese source as the Dasheng baifa mingmen lun kaizong yijue 大乘百法明門論開宗義決 (“Resolution [on How to] Clarify the Tenets of the Mahāyānaśatadharmaprakāśamukhaśāstra,” T. 2812), an exegetical work on the *Mahāyānaśatadharmaprakāśamukhaśāstra, composed by the famous Dunhuang-based Chinese monk Tankuang 曇曠. The Resolution borrows a full version of the Mahādeva narrative from the Mahāvibhāṣā 阿毘達磨大毘婆沙論, casting it as the trigger of the first schism. I offer close readings and English translations of the relevant content of IOL Tib J 26 and the Resolution, not only to substantiate my identification, but also to offer an example of how native Chinese Buddhist texts were conveyed in Tibetan compositions.
“Turned into a Different Person”
Authors: O’Neil Michael D.
Published: September 2024

Karl Barth’s final volume of his Church Dogmatics includes a subsection entitled “Baptism with the Holy Spirit” as part of his discussion of the foundation of the Christian life (Church Dogmatics IV/4, 2–40). Analysis of this subsection shows that Barth conceives of this “baptism” as a person’s conversion, the beginning of human faithfulness toward God. As such, it is very different from typical pentecostal construals of the doctrine, which perhaps accounts for the surprising paucity of pentecostal engagement with this subsection. This essay presents a detailed analysis of Barth’s doctrine and shows that it includes significant resonances with pentecostal doctrine, despite obvious differences. It argues that Barth’s doctrine might help Pentecostals retain the charismatic and missional emphases of their doctrine within a broader theology of the Spirit’s work in the Christian life. The essay suggests several points of dialogue between Barth and Pentecostals in which both parties might benefit from the other’s insights, illustrating this possibility with a larger discussion of the issue of subsequence.
An Approach to Maritime Cyber Security Risks: Nature and Countermeasures
Authors: Kim Suk Kyoon
Published: September 2024

Maritime cyber risks, due to digitalisation, automation and operational integration in the maritime sector, have emerged as a new threat to maritime security. The rapid increase in maritime cyberattacks, with far-reaching consequences, requires the maritime sector and international community to address cyber security threats. In a global world, the consequences of a cyberattack affecting the transportation system of a country or a single terminal can quickly cascade across, and disrupt, the entire global supply chain. Thus, like piracy, maritime cyber security should be approached from a global governance perspective.
The Formosan Christians for Self-Determination Movement: a Case Study of Overseas Taiwanese Christian Political Activism in the 1970s
Authors: Shen Yun-Ching
Published: September 2024

In the 1970s, four overseas Taiwanese Christians launched the “Formosan Christians for Self-Determination Movement” (FCSDM) in the United States to promote the self-determination of the people of Taiwan. This article draws on three policy documents released by the FCSDM to argue that these Christians apparently embedded the Christian understanding of human rights within the secular political discourse of self-determination and sovereignty. In so doing, they strove to appeal to people from a broader spectrum of religious and national backgrounds rather than merely addressing Taiwanese Christians in their call for Taiwan’s self-determination.
Approche multimodale de l’enfant apprenti-énonciateur
Authors: Morgenstern Aliyah
Published: September 2024

Language arises from interactions via different types of semiotic resources that have been sedimented and have specialized throughout collective and daily experiences. Interactions with adults provide children with the semiotic resources necessary to construct language and their own positioning. They learn to understand and link language to actions and activities during their daily experiences through the development of repeated multimodal scripts. In this paper, we use a multimodal approach to analyze the transmission of language and its appropriation by children in an ecological context. The objective is twofold. On the one hand, we try to show the primordial role of adults who integrate all children’s relevant behaviors in the dialogue by co-constructing meaning. On the other hand, we illustrate how children progressively learn to coordinate the semiotic resources at their disposal, varying the use of these resources according to their specificities, their availability and their own interactional needs.
Species circumscription within the Rediviva neliana group (Hymenoptera: Melittidae), with the description of the new species Rediviva volgeli sp. nov. Melin & Colville
Authors: MELIN ANNALIE , MANNING JOHN C. , COLVILLE JONATHAN F.
Published: September 2024

Rediviva neliana Cockerell 1931 has been considered to be widely distributed along the southeastern and eastern Escarpment of South Africa and Lesotho, with high variation in foreleg length recorded across populations. A recent analysis of the allometric relationship between foreleg length and body size for the oil-collecting species of Rediviva revealed that R. neliana is a notable ‘outlier’, suggesting that it represented a group of species and not a single taxon. This hypothesis necessitates a critical review of the taxonomy of R. neliana. Here, we examined a large amount of old (n = 1228) material as well as more recent material collected from 23 different sites across the Great Escarpment, including the resurveying of type localities. Based on this, we (i) redescribe the male of R. neliana and the previously unknown female; (ii) reinstate R. politissima (Cockerell 1934) stat. rev. from synonymy with R. neliana, and redescribe both the male and female; (iii) reassign the male of R. whiteheadi Kuhlmann 2012 to R. autumnalis Whitehead & Steiner 2008, and include the female of R. whiteheadi syn. nov. into synonymy with R. neliana; (iv) reassign 242 specimens of R. neliana to R. steineri Kuhlmann 2012, thus vastly expanding the known distribution of the latter taxon; (v) describe both sexes of the new species R. vogeli Melin & Colville sp. nov.; and (vi) provide a revised key to the species of Rediviva occurring in the southern African summer-rainfall region based on the shape of the galea and male genitalia. Detailed images of genitalia and hidden sterna are also provided for all species of Rediviva in the summer-rainfall region for which males are known. We conclude that the R. neliana group comprises four species. Understanding their geographic distributions is relevant to assessing their conservation status and understanding their coevolution with host plants.
A new species of stauromedusa, Calvadosia festivala (Cnidaria: Staurozoa: Kishinouyeidae) from India
Authors: BAROLIYA HITISHA ISHAWARBHAI , KUNDU RAHUL , MIRANDA LUCÍLIA SOUZA
Published: September 2024

Staurozoa is a cnidarian class represented by marine benthic animals, mainly observed in intertidal and subtidal cold waters. As one of the few exceptions, in this study we described a tropical species, Calvadosia festivala n. sp., from Dwarka, Gujarat, India. We combined the morphological description with molecular data, placing the new species into a phylogenetic context with other species of Calvadosia. Calvadosia festivala n. sp. is unique in the arrangement of white nematocyst spots and in the dark (purplish brown) lines in the nodular gonads and in manubrium. The new species is closely related to Calvadosia lewisi, Calvadosia corbini, and Calvadosia tasmaniensis, sharing the pad-like adhesive structures on the exumbrellar tips of arms, externally separated from the secondary tentacles. This is the first formal description of a staurozoan species from India, the fourth species of Staurozoa described for the Indian Ocean, and the fourth recorded in tropical waters, providing relevant data to biogeographic and diversity discussions on the group.
Diagnostic utility of brain MRI volumetry in comparing traumatic brain injury, Alzheimer disease and behavioral variant frontotemporal dementia
Authors: Raji Cyrus A. , Meysami Somayeh , Porter Verna R. , Merrill David A. , Mendez Mario F.
Published: September 2024

Background

Brain MRI with volumetric quantification, MRI volumetry, can improve diagnostic delineation of patients with neurocognitive disorders by identifying brain atrophy that may not be evident on visual assessments.

Objective

To investigate diagnostic utility of MRI volumetry in traumatic brain injury (TBI), early-onset Alzheimer disease (EOAD), late-onset Alzheimer disease, and behavioral variant frontotemporal dementia (bvFTD).

Method

We utilized 137 participants of TBI (n = 40), EOAD (n = 45), LOAD (n = 32), and bvFTD (n = 20). Participants had 3D T1 brain MRI imaging amendable to MRI volumetry. Scan volumes were analyzed with Neuroreader. One-way ANOVA compared brain volumes across diagnostic groups. Discriminant analysis was done with leave-one-out cross validation on Neuroreader metrics to determine diagnostic delineation across groups.

Result

LOAD was the oldest compared to other groups (F = 27.5, p < .001). There were no statistically significant differences in sex (p = .58) with women comprising 54.7% of the entire cohort. EOAD and LOAD had the lowest Mini-Mental State Exam (MMSE) scores compared to TBI (p = .04 for EOAD and p = .01 for LOAD). LOAD had lowest hippocampal volumes (Left Hippocampus F = 13.1, Right Hippocampus F = 7.3, p < .001), low white matter volume in TBI (F = 5.9, p < .001), lower left parietal lobe volume in EOAD (F = 9.4, p < .001), and lower total gray matter volume in bvFTD (F = 32.8, p < .001) and caudate atrophy (F = 1737.5, p < .001). Areas under the curve ranged from 92.3 to 100%, sensitivity between 82.2 and 100%, specificity of 78.1-100%. TBI was the most accurately delineated diagnosis. Predictive features included caudate, frontal, parietal, temporal lobar and total white matter volumes.

Conclusion

We identified the diagnostic utility of regional volumetric differences across multiple neurocognitive disorders. Brain MRI volumetry is widely available and can be applied in distinguishing these disorders.
Association between removable prosthesis-wearing and pneumonia: a systematic review and meta-analysis
Authors: Lim Tong Wah , Li Kar Yan , Burrow Michael Francis , McGrath Colman
Published: September 2024

Background

A high burden of respiratory pathogens colonizing removable prosthesis surfaces suggests the potential of association between removable prosthesis-wearing and respiratory infections. Therefore, this systematic review and meta-analysis aimed to evaluate the evidence from clinical studies concerning the association between removable prosthesis-wearing and respiratory infections.

Methods

Clinical studies that reported respiratory infections associated with adult patients wearing removable prostheses in any centers (hospitals and nursing homes) or communities were included. Literature was searched across five electronic databases (MEDLINE, Cochrane Library, EMBASE, Web of Science, and Scopus) to 28 May 2024. An additional search was performed for unpublished trials and references cited in related studies. The Newcastle-Ottawa Scale was employed for the quality assessment. The certainty assessment was established using GRADE. The results were pooled using a frequentist random-effects meta-analysis and the odds ratios generated.

Results

A total of 1143 articles were identified. Thirteen articles had full-text articles screening and an additional two articles were added through reference linkage. Ultimately, six non-randomized clinical studies reporting various types of pneumonia contributed to this review. Overall odds of having pneumonia among prosthesis wearers were 1.43 (95% CI: 0.76 to 2.69) and 1.27 (95% CI: 1.11 to 1.46) using the random- and fixed-effects models, respectively. The heterogeneity in the meta-analysis was substantial. In subgroup analysis according to the study design, the heterogeneity within prospective studies was much reduced, I2 = 0% (p = 0.355). The certainty of the evidence evaluated using the GRADE approach was low to very low evidence for prosthesis wearers developing pneumonia based on studies.

Conclusions

There was no conclusive evidence from the non-randomized clinical studies supporting whether prosthesis-wearing is a risk factor for pneumonia based on outcomes from this review.