bluuebunny/crossref_metadata_2025 huggingface dataset:
On the quantum model of a charged black hole
Authors: Gladush V. D.
Published: May 2022

We study the quantum states of the black hole model in the configuration space. To this end, we investigate the properties of the configuration space of the Einstein–Maxwell set of equations in the T-region. We limit ourselves to considering the T-region, where the fields under consideration have a dynamic meaning. Based on the standard action for the of Einstein–Maxwell set of equations, we construct the reduced action for the spherical symmetry case. Using the Hamiltonian constraint, we exclude the non-dynamic degree of freedom from the reduced action, thereby passing to the configuration space. In the new representation of the system, we study the induced dynamical system in the configuration space. It turns out that the induced supermetric is reduced to a quasi-Cartesian form. The laws of charge and mass conservation, which the system contains, together with the Hamilton constraint, completely determine thestate of the black hole. They allow one to find the momenta and the action of the system in terms of field variables and conserved quantities, as well as the trajectory of motion in the configuration space. The black hole quantization is reduced to the construction of the quantum states for the system with a fixed mass and charge in a three-dimensional pseudo-Euclidean configuration space The Hamilton constraint is associated with the DeWitt equation, the latter is constructed using the Laplace–Beltrami operator, which is Hermitian with respect to the natural measure. To construct a Hermitian mass operator, it suffices to restrict ourselves to partial derivatives with their corresponding ordering. For the physical states satisfying the DeWitt equation to be also eigenfunctions of the mass operator, the compatibility conditions must be satisfied. In this case, we arrive at the corresponding ansatz. Its substitution into the DeWitt equation leads to a self-consistent solution of the quantum DeWitt equation and equation for the eigenvalue of the mass operator. The constructed model describes the quantum states of a charged black hole in the configuration space with continuous mass and charge spectra.
The Establishment of the Royal Hungarian State School of Lacemaking in Körmöcbánya (Kremnica) and Its Impact on the Lacemaking Cottage Industry in the 20th Century
Authors: Erdei T. Lilla
Published: May 2022

The Royal Hungarian State School of Lacemaking in Körmöcbánya was the earliest independent institution in the field of Hungarian bobbin lacemaking. Unfortunately, there is little information available about the school, largely due to the revision of national borders as a result of the Treaty of Trianon. Following a survey of what remained of the lacemaking cottage industry in Upper Hungary [now mostly present-day Slovakia], teaching was organized from 1883 in itinerant workshops in Bars and Zólyom counties (in Úrvölgy, Sóvár, Eperjes, and Hodrusbánya). Annual training courses, as part of a school-based teaching system, were introduced probably in around 1894, and from 1899 yearbooks were published by the Royal Hungarian State School of Lacemaking in Körmöcbánya. Until 1909 (with the exception of the 1888/89 academic year), Körmöcbánya functioned as the administrative center, while teaching took place in local schools, first in Jánoshegy and subsequently in Óhegy, Jánosrét, Kunosvágás, and Kékellő, where schools opened in succession. Poorer students were awarded scholarships to participate in the two-year training, and those who wished to work in the cottage industry were given employment following graduation. Besides introducing the readily marketable Carlsbad, Idrija, Cluny, and Torchon lace patterns that were taught at the school, Béla Angyal was the first to expand the treasury of Upland lace patterns with the addition of new Hungarian designs, while Emília Angyal was responsible for their technical elaboration. For a while, state-sponsored lacemaking in Upper Hungary provided a relatively good livelihood for the female members of working families, although this situation changed with the influx of cheap foreign lace, and especially with the spread of mass production. Besides popular foreign patterns and techniques, the school in Körmöcbánya also played an important role in the spread of new tools in Hungary.
Monitoring of soybean germination process by near-infrared spectroscopy
Authors: Bartalné-Berceli M. , Izsó E. , Gergely Sz. , Salgó A.
Published: May 2022

Soybean seeds were germinated on an industrial scale after soaking for 0–56 h to produce a special additive for food industrial use. The germination process of three soybean varieties was monitored with near-infrared (NIR) spectroscopy based on changes in the amount, status, or character of the water. This paper evaluates the “waterless” NIR spectra of sound, germinated, and heat treated seeds to try to follow the fine details of the germination process. The germination process was analysed with the help of cluster analysis (CA), principal component analysis (PCA), and polar qualification system (PQS) as statistical and chemometric methods. PCA proved to be the most sensitive spectrum evaluation method to follow the fine details of germination. The applied NIR method is suitable for non-destructively, real-time monitoring of the non-linear nature of germination.
Fieldwork
Authors: Jamal Thornton Brendan
Published: May 2022

Fieldwork, a term frequently employed in religious studies to describe qualitative research with contemporary subjects in their own milieu, is a concept inextricably linked with the ethnographic project. Anthropologists have for years challenged and pushed the limits of what fieldwork is, where fieldwork takes place, and how fieldwork is conducted by asking productive questions about where exactly “the field” is located and what precisely constitutes “the work”. In religious studies, debates about ethnographic fieldwork, per se, are less advanced. Traditional notions of fieldwork in anthropology assume long-term engagement with folk and their communities. This often means living and working with research subjects for years, even decades. A critical reflection on the method and idea of fieldwork in religious studies brings to the fore important issues of legitimacy, accuracy and comprehensiveness in the study of “lived religion” and raises anew enduring questions about the ethics of ethnography when time, access and intimacy are ever-shifting and precarious.
Barker, Eileen, and Beth Singler, eds. 2022. Radical Transformations of Minority Religions.
Authors: Beckford James A
Published: May 2022

Barker, Eileen, and Beth Singler, eds. 2022. Radical Transformations of Minority Religions. London: Routledge. xv + 275 pp. ISBN: 978-0-415-78670-6. £120.00 (hbk).
Thomas, Aled. 2021. Free Zone Scientology: Contesting the Boundaries of a New Religion.
Authors: Graham-Hyde Edward
Published: May 2022

Thomas, Aled. 2021. Free Zone Scientology: Contesting the Boundaries of a New Religion. London: Bloomsbury. 190 pp. ISBN: 978-1-3501-8254-7. £85.00 (hbk).
Roberts, Thomas B. 2019. MindApps: Multistate Theory and Tools for Mind Design.
Authors: Lutkajtis Anna
Published: May 2022

Roberts, Thomas B. 2019. MindApps: Multistate Theory and Tools for Mind Design. Rochester, VT: Park Street Press. xii + 212 pp. ISBN: 978-1-62055-818-8. US$17.99 (pbk).
Banana inflorescence and their potential health benefits as future food
Authors: Chowdary Madineni Yogitha , Rana Sandeep Singh , Ghosh Payel
Published: May 2022

Banana scientifically known as Musa sp. is a famous tropical fruit majorly cultivated in India with a production of 29 million tonnes. One of the underrated parts of the banana plant is the edible flower (banana inflorescence/blossom) which can be utilized in several ways for nutritional and therapeutic purposes as it is known to have potential antioxidant, anti-carcinogenic, and anti-diabetic properties. The present paper primarily focuses on the health benefits of banana inflorescence and the bioactive components responsible for its properties. Secondly, the paper describes different traditional dishes of banana blossom made in India highlighting the regionality, ingredients used, and preparation procedures with a view to popularize these ethnic delicacies and functionality of banana blossom among other parts of the world. In India, several different dishes and pickles are prepared with the blossoms. They are used as functional foods and are mentioned in detail in this paper.
REPORTS
Authors: Filipenko Volodymyr , Zolotareva Svetlana
Published: May 2022

Report on the work of centers and associations of orthopedists-traumatologists
EXPERIMENTAL STUDY OF OSTEOSYNTHESIS STABILITY OF THE DISTAL PART OF THE HUMERUS
Authors: Bodnya Оlexander , Dubovik Sergey , Karpinsky Mykhaylo , Karpinska Olena
Published: May 2022

Unresolved issue is improving of the osteosynthesis of extraarticular fractures of the distal humerus. Search for a simplified method of biological fixation, which assumes, with low trauma, to ensure the stable fixation of fragments and movements in the elbow joint in the early postoperative period. Objective.To carry out a comparative analysis of the bone fragments displacement of the distal humerus in extra-articular fractures, stabilized by extraosseous and transosseous osteosynthesis. Methods. Biomechanical study of the distal humerus model was made. Transosseous osteosynthesis was modeled using the author’s external fixation apparatus (EFA). For comparison, we chose an osteosynthesis with a Y-shaped plate. The humeral models were loaded with an interval and a stepwise increased in the load for compression along the axis, flexion in a parallel plane, as well as perpendicular to the fixing elements of the plate and EFA. The magnitude of the load gradually increased from 0 to 250 N with a step of 50 N. The magnitude of the forces at which, due to the action of various loads, a displacement at the level of the fracture appeared. Results. The analysis of experimental studies showed that the rod apparatus and the plate provide the same stability of fixation of the fragments of the humerus under conditions of axial compression load (p > 0.05). Under the influence of bending loads of more than 100 N in a plane parallel to the fixing elements, the plate had a slight advantage (10 %). A significantly better result (p < 0.01) was obtained when an external device was used under the action of bending loads in a plane perpendicular to the fixing elements. Conclusions. In the case of fractures of the distal humerus, the transosseous osteosynthesis using the proposed external fixation rod device ensures the stability of the fragments under all loading options. It is quite reliable and can be recommended for use in clinical practice.
PRACTICAL ASPECTS OF INTRAOPERATIVE NEUROMONITORING IN PATIENTS WITH DIFFERENT SPINAL PATHOLOGIES
Authors: Barkov Oleksandr , Duplii Diana
Published: May 2022

Objective. To study the operating parameters and phenomena of intraoperative monitoring and to identify the specificity and sensitivityof its different modalities associated with postoperative neurological complications in patients with different spinal pathologies.Methods. The intraoperative neurophysiological monitoring (IOM) protocols of 88 patients who underwent spinal surgeries were analyzed:kyphoscoliotic spinal deformities — 58 (68 %), traumatic — 12 (13.3 %), degenerative diseases — 10 (11.7 %), neoplasms — 6 (6.7 %). In 33 (38.4 %) cases, a combination of modalities of motor evoked potentials (MEP) and transpedicular screws stimulation (TSS) was used, in 36 (41.9%) — only MEP, 17 (19.8 %) — TSS. In all cases, freerun and triggered EMG was used. Results. The most stable MEPs were recorded at mm. tibibalis anterior, mm. abductor hallucis longus. It has been proven that an unfavorable and reliable factor of the anxiety sign is a unilateral sustained decrease in the MEP amplitude by more than 80 %. According to the TSS results 424 (97.5 %) screws are installed correctly, 1 (0.2 %) false negative case of incorrect installation. False positive results for the TSS test ranged from 34.7 to 15.4 %, depending on the chosen critical threshold of the current applied to the pedicle screw. We consider the threshold of the TSS test at 13 mA satisfactory, and below it, unsatisfactory. A group of patients was identified who had 72 screws (16.6% of all analyzed) who, according to the results of the TSS test, received an unsatisfactory assessment, and X-ray did not reveal any deviations in the position of the screws.Conclusions. IOM modalities are highly sensitive and specific to damage to the structures of the spinal cord and spinal nerves, but dependence on a number of external factors reduces their information content, which leads to false positive and false negative results. It was established, that the dynamics of the MEP amplitudes of the target muscles differs in information content and efficiency during surgery due to individual morphological and motor characteristics.
Answer of article’s authors «Peculiarities of surgical correction of different forms hand syndactylly in children. Retrospective study of own experience»
Authors: Harbuzniak I. M. , Hrytsenko A. M.
Published: May 2022

Answer of article’s authors «Peculiarities of surgical correction of different forms hand syndactylly in children.Retrospective study of own experience»
TRAINING AND PRACTICE-CENTRIC METHOD OF PROFESSOR SULYMA
Authors: Sulyma Vadym , Filiak Yuliia , Madii Marta
Published: May 2022

The paper is concerned with the current state of doctors’ training methodologies. Problems of teaching the discipline were identified: inability to memorize the amount of theoretical material, the ineffectiveness of methodological techniques for practical training, amount of new training centers. It has been proven that these faults are risky for mastering learning skills. The method of «see - repeat»preferred by coachers is not a panacea for the effective educational process during various medical interventions. Particular attention is paid to the psychological borders of young doctors in the recollection of new information that is needed to be improved. Objective. Build an innovative methodological strategy that requires a combination: high quality of theoretical medical knowledge and practical skills. Results. Among modern pedagogical techniques, the most profitable is the method of Peyton, which became the base of «Professor’s Sulyma training». Detailed instruction of the author's teaching strategy is suggested in the report. This way of education is based on neurobiological research and divided into 10 stages, which are theoretically and methodically described. The authors approbated training and paid attention to its effectiveness. Conclusions. «Professor’s Sulyma training» is a method that allows practicing any valuable skills in different medical areas
Culprit-Only Versus Complete Revascularization in STEMI Multi-Vessel Disease: A Case Report
Authors: Putri Mega Amanda , Yahya Achmad Fauzi , Dewi Triwedya Indra
Published: May 2022

Objective: To revisit data and highlight management of STEMI multi-vessel disease and explore culprit-only versus multi-vessel PCI and optimal timing to achieve complete revascularization. Methods: A 67 years old male with chest pain at rest 2 hours before admission with a history of smoking one pack of cigarette every day, was presented to the hospital. Physical examination was within normal limit with normal hemodynamically; however, elevated cardiac troponin was identified. Electrocardiogram showed STEMI anteroseptal wall with ischemic inferior wall, leading toSTEMI anteroseptal wall, Killip I diagnosis. Primary PCI was performed and multi-vessel disease was found. A complete revascularization single-staged procedure was performed due to his persistent chest pain. PCI of these coronary stenoses is beneficial to reduce risk of cardiac death and recurrent infarction. However, some issues related to PCI of non-culprit coronary arteries lesion and optimal timing to do complete revascularization is still a dilemma. Results: Related to data from some trials, e.g PRAMI, CvLPRIT, DANAM-3-PRIMULTI, COMPARE-ACUTE, COMPLETE, and some meta-analyses, showed benefit and safety of routine PCI of non-culprit lesions as a preventive strategy to reduce morbidity and mortality. Data showed reduce future morbidity and mortality in this setting. Meanwhile, the optimal timing of complete revascularization is still a matter of debate, although some data showed benefit of index procedural PCI. Conclusion: PCI of non-culprit lesions of myocardial infarction is consistently beneficial over culprit-only revascularization in patients with STEMI multi-vessel disease, despite the debate on the optimum timing for complete revascularization in this setting.
Analysis of Epistemic Gatekeeping Engendered by Abstruse Academic Cant in STEM and HUMSS : Analysis of Elitist, Inaccessible Academic Language in Science and Humanities
Authors: Irfan Hanan Khaja Mohammad
Published: May 2022

The paper attempts to analyse the existence of explicit elitist linguistic trends when it comes to choice of words, syntax, context, jargon and the overall English language in academic and scholarly works. It further questions the impact such linguistic trends have on accessibility
and readability of academic works. The paper intends to analyse the development of formalism and structuralism in academic writing and juxtaposes it with the advocacy of academic simplism. The mode of analysis is data driven, taking into account various respondents from the Indian disapora
to answer their experiences with regards to their participation in academia. Academia is plagued by a quotidian overcomplexity, and technical cant that render an already complicated subject further unreadable for the masses. This paper analyses the public opinion on the same and the reasons
behind such self-sabotaging academic practices.
Anurans from the upper basins of the Rio Grande and Rio Preto: eastern portion of the Serra da Mantiqueira Environmental Protection Area, state of Minas Gerais, Brazil
Authors: Lima M. S. C. S. , Pederassi J. , Sampaio W. D. , Pineschi R. B. , Souza C. A. S. , Nascimento J. A. C. , Caramaschi U.
Published: May 2022

Abstract The Neotropical zone stands out for having the greatest richness of amphibians in the world. About 625 species of anurans are known on Atlantic Forest. The southeastern mountainous regions of Brazil called Serra do Mar and Serra da Mantiqueira, are very important areas for the diversity of anurans in the country because they shelter remaining strata of the Atlantic Forest that have several endemic species. The present study aims to expand the knowledge about the Serra da Mantiqueira anurans, specifically from the Rio Preto and Rio Grande upper basins. The study area comprised 10 sample centers. We realized 38 campaigns, lasting two days each. During this period, we used active search as visual and auditory cues. The passive search was comprised of pitfall traps. Bioacoustic analyses were used to determine the cryptic species. The sufficiency of the sampling effort was estimated through the accumulation curve using Bootstrap and Jackknife-1 as estimators. During the study 55 species were found, 40 of them in the basin of the Rio Preto, and 44 in the basin of the Rio Grande. Twenty-nine species were found in both areas. The Hylidae family was predominant, followed by Leptodactylidae. In addition to species of the Atlantic Forest, the place houses typical components of the Cerrado biome and altitudinal swamps with unexpected sympatries. This inventory expands the area of occurrence of Scinax duartei, a species considered threatened. Although adjacent to the oldest national park in Brazil, the composition of anuran species of this area was unknown until then.
[RETRACTED ARTICLE] Evaluating the secondary bioactive metabolites in Geodia corticostylifera
Authors: Abdelbasset W. K. , Bokov D. O. , Jasim S. A. , Yasin G. , Abbas H. , Alkadir O. K. A. , Taifi A. , Jalil A. T. , Aravindhan S.
Published: May 2022

Abstract Ophiactis savignyi could be discovered all over the world in tropical marine environments. People could have aided in the spread of O. savignyi, particularly in the western and eastern populations of Panama's Isthmus. The brittle star Ophiactis savignyi, often known as savigny's brittle star, coexists alongside the sponge Geodia corticostylifera. The focus of this research has been to assess the functional relevance of G. corticostylifera secondary metabolites as antifoulant against mussels, protection against generalist fish, and chemical cues to affiliated brittle stars. Both in flow-through and static seawater laboratory studies, O. savignyi which has previously been connected with sponges, was given both treated and control mimics at the same time. The sponge extract was also tested for its ability to protect fish against predators and fouling. Deterrence test using chemicals indicated that the normal level of the sponge extract may also suppress generalist fish predation in the field as well as the mussel Perna perna’s normal attachment in clinical contexts. According to the findings, G. corticostylifera crude extract has many roles in the aquatic environments, apparently being accountable for this sponge's tighter relationship with O. savignyi, which protects the ophiuroid and inhibits epibionts on itself.
Influência dos fundos de investimento na formação das cotações do milho na Bolsa de Cereais de Chicago
Authors: Brum Argemiro Luís , Baggio Daniel Knebel , Souza Francisca Mendonça , Batista Guilherme , Schneider Isoé Nícolas
Published: May 2022

Resumo: Este artigo buscou detectar a influência do posicionamento dos fundos de investimento junto ao mercado de commodities a partir do comportamento das negociações do milho na Bolsa de Cereais de Chicago (CBOT). Respondendo assim ao problema: qual a dimensão da influência dos fundos de investimento na formação das cotações do milho na CBOT? O objetivo foi verificar, dentro do período de 2006 a 2009, quanto a atuação destes fundos interfere na formação dos preços do cereal, pois as cotações em Chicago servem de balizador à formação dos preços do cereal no mercado físico mundial e no brasileiro em particular, impactando assim no desenvolvimento regional. A metodologia adotada foi análise inferencial dos dados, a partir de análises de correlação e de regressão múltipla, usando-se o coeficiente de correlação de Pearson (r); o coeficiente de determinação R2; e o coeficiente de determinação ajustado, além de análise de regressão a partir da estimação stepwise. Nos resultados obtidos destaca-se que, ao analisar somente posições dos especuladores, fundos de investimentos e pequenos investidores, sem a presença dos investidores comerciais, 45,3% da formação do preço futuro do milho pode ser explicado pela negociação desses grupos, onde a participação dos fundos de investimento é significativa.
Relations of power and oppression within the delivery room: nursing narratives
Authors: Yolanda Rangel-Flores Yesica , Magdalena Martínez-Villa Consuelo , Jiménez-Arroyo Vanesa
Published: May 2022

ABSTRACT Objective: To analyze, from the perspective of decolonial feminism, the power and oppression relations experienced by nurses in the delivery room in a hospital in Mexico. Method: Qualitative study in which 15 nurses selected by theoretical sampling were interviewed. The interviews were fully transcribed and subsequently analyzed using content analysis. Results: The emerging central category was “Inter- and intragender power/oppression relations” and psychological and symbolic violence were the most frequent types. Gender was confirmed as the most important structural determinant of oppression, cutting across bodies and professional identities. The conditions contributing to intragender conflict are age, expertise, and specialization. Three coping resources were documented: defenselessness, complicity and resistance. Conclusion: It is necessary to denaturalize the forms of power/oppression sustained by gender inequalities, but also to discuss other conditions that determine power/oppression relations between women and colleagues. Eradicating intra-gender and intergender violence is necessary to access safe working environments that promote creativity for the exercise of care.
Táticas de desmoronamento em teatro: sobre a urgência de sobreviver e levantar-se
Authors: Vasconcelos Gisele Soares de , Machado Nicolle Silva
Published: May 2022

RESUMO O artigo evoca o arcano A Torre como alegoria para discorrer sobre táticas de desmoronamento na pesquisa-montagem de A Vagabunda, Revista de uma mulher só, desenvolvida em tempos pandêmicos com produção do grupo Xama Teatro (Brasil - MA). O texto revela possíveis alternativas para uma escrita conjugada do texto e da cena, baseada em experiências de vulnerabilidade, acolhendo o desmoronamento como tática para gerar um processo que se retroalimenta a todo instante. Como procedimentos, se destacam: a prática de improvisação em ateliê; a escolha de referências e mapeamento de temáticas; a exploração de problemas e experimentação de programas como modos de insistir e de sobreviver à pandemia de covid-19.
Collapse tactics in performing arts: on the urgency of surviving and standing up
Authors: Vasconcelos Gisele Soares de , Machado Nicolle Silva
Published: May 2022

ABSTRACT This article evokes The Tower tarot card as an allegory to discuss collapse tactics within a specific performing arts project: the research staging process of the play The Vagabond, a One-Woman Music-Hall Show, developed during the Covid-19 global pandemic and produced by the Xama Teatro group (Maranhão state, Brazil). It reveals possible alternatives for a combined writing process of both script and staging, based on experiences of vulnerability and drawing on collapse as a tactic to provoke a process that constantly feeds back into itself. The procedures that stand out in the process are: improvising in an atelier environment; choosing references and mapping thematic fields; exploring problems; and experimenting with performative programs as a means to insist on surviving the Covid 19 global pandemic.
CONSTRUÇÃO SOCIAL DAS ESCOLHAS E DESTINOS ESCOLARES: MULHERES NEGRAS DA LICENCIATURA EM QUÍMICA DO IFRJ-CDUC
Authors: Heidelmann Stephany P. , Candau Vera Maria F.
Published: May 2022

Considerando a complexidade da trajetória formativa docente e as possibilidades que esta traz na construção das subjetividades e da identidade dos professores, o presente trabalho buscou analisar o perfil de alunas e egressas negras do curso de Licenciatura em Química do Instituto Federal do Rio de Janeiro – campus Duque de Caxias. Portanto, uma articulação entre os conceitos de Pierre Bourdieu com estudos da área e alguns autores negros, como Silvio Almeida, é proposta para problematizar a inserção feminina negra e os dispositivos mobilizados para tal. A análise é realizada a partir dos dados obtidos na aplicação de vinte e oito questionários semiestruturados online e realização de quinze entrevistas individuais, também online. A partir dos resultados, tornou-se possível verificar o perfil das participantes e identificar o racismo estrutural no que tange a construção da escolha do curso pelas participantes, muito pautada por aquilo que é mais realizável considerando sua origem social. Ao mesmo tempo, evidencia-se ao longo do estudo que muitas são as primeiras gerações de suas famílias a acessarem o ensino superior, o que traz também uma influência para as gerações posteriores. Ao longo do trabalho observa-se diversos mecanismos e condições sociais que se tornam determinante para as escolhas e inserções das mulheres negras no campo acadêmico.
ANÁLISE IMUNOISTOQUÍMICA DO BIOMARCADOR CICLINA D1 NOS CARCINOMAS PAPILÍFEROS DE TIREOIDE E BÓCIOS MULTINODULARES
Authors: Bartolomei Ivan José Paredes , Ribas Carmen Austrália Paredes Marcondes , Zella Maria Augusta Karas , Waaga-Gasser Ana Maria , Gasser Martin , Czeczko Nicolau Gregori , Nassif Paulo Afonso Nunes
Published: May 2022

Racional - Os carcinomas papilíferos são os mais prevalentes e menos agressivos de tireoide (CPT). Em alguns casos, o diagnóstico é duvidoso e o prognóstico ruim. A busca de biomarcadores teciduais que permitam assegurar tanto o diagnóstico para casos indeterminados, quanto o prognóstico, identificando os casos de maior agressividade, têm sido estudadas nas últimas décadas. Objetivo: Analisar a ciclina D1 nos CPT e nos bócios multinodulares (BMN) e verificar a correlação da marcação com as características clinicopatológicas. Métodos: Foram selecionados 118 tecidos de pacientes adultos submetidos àa tireoidectomia por CPT e 40 BMN como grupo controle. Realizou-se imunocoloração tecidual com ciclina D1 com subsequente análise imunoistoquímica em ambos grupos, avaliando-se a expressão do marcador (intensidade e distribuição). No grupo dos CPT os dados da imunocoloração foram também cruzados com os dados clinicopatológicos. Resultados: A maioria (93,3%) expressou a coloração da ciclina D1 com intensidades variadas (fraca, moderada e forte) e distribuição predominantemente difusa (71,2%). O grupo controle dos BMN, expressou coloração para ciclina D1 em 57,5%, com intensidade fraca (47,5%) e distribuição esparsa (37,5%). A diferença entre os grupos (estudo e controle) foi estatisticamente significante (p<0,001). No grupo dos CPT, os cruzamentos clinicopatológicos não evidenciaram diferenças quanto à idade, sexo, tipo e tamanho tumoral, estado linfonodal, focalidade e invasão angiolinfática. Conclusão: A ciclina D1 foi expressa na grande maioria dos CPT sendo a distribuição difusa predominante. Não houve correlação entre a expressão delacom qualquer característica clinicopatológica dos CPT.
1915Çanakkale Bridge, Turkey: challenges and achievements of deck erection over the Dardanelles
Authors: Ascaso Til Mercedes , Sancho Santamaría Alberto , Lopez Nicholas Luis
Published: May 2022

The 1915Çanakkale Bridge spans the Dardanelles at the western end of the Sea of Marmara. Part of the Kinali–Balikesir motorway in the northwest of Turkey, it is the longest suspension bridge in the world. The 2023 m long main span leaves a 1600 ×  70 m navigation channel. Two 318 m steel towers support the main suspension cables at 38 m separation. The deck comprises a pair of 14.5 m wide, 3.5 m deep aerofoil steel box girders connected at intervals by transverse box girders. Eight 450 t capacity lifting gantries were required for deck erection, two for each side span and four for the main span. There were 153 deck segments to be erected, of which 143 were erected with the gantries. The gantries were self-erected onto the main cables. Environmental conditions and maritime traffic in the strait were key factors in the development and choice of construction methods for the bridge. This paper describes deck erection with the lifting gantries and focuses on the development, design, testing and operation of the self-erection system – an innovative solution which maximises pre-assembly off the critical path, minimises disruption to shipping and allows installation of the gantries without floating cranes.
Relation of anxiety and hopelessness levels of healthcare employees with personality traits during Covid-19 period
Authors: TAŞCI Gülay , ÖZSOY Filiz
Published: May 2022

Aim: Corona Virus Disease-2019 (COVID-19) is an acute respiratory infection that began in Wuhan province in China, and spread to many countries around the world. A limited number of studies were conducted in the literature to evaluate the mental health of healthcare employees during the COVID-19 period. The purpose was to evaluate the relation of the anxiety and hopelessness levels caused by COVID-19 pandemia period with personality traits of healthcare employees.
Material and Methods: A total of 451 people participated in our study; including 221 healthcare employees and 230 non-medical community sampling. All participants filled the Coronavirus Anxiety Scale (CAS), Beck Hopelessness Scale (BHS), Revised Eysenck Personality Survey-Shortened Form (EPS-RCF).
Results: All the subscale scores of CAS and BHS were found to be high in healthcare employees. The EPS-RCF Neurotism subscale was also found to be high in healthcare employees. During the COVID-19 period, the anxiety and hopelessness levels of healthcare employees were found to be higher than non-medical community sampling. It was also found that the personality trait of Neurotism was dominant in healthcare employees, and that personality traits were associated with both anxiety and hopelessness levels.
Conclusion: Our findings are very important for healthcare employees all over the world to reduce their anxiety, to increase future expectations, motivations and hopes for the future, and to be spiritually good during this pandemia period.
Teorija racionalnog izbora – alternative i kritike
Authors: Krstić Miloš
Published: May 2022

Temeljne postavke teorije racionalnog izbora su sljedeće: (A1) ponašanje se može objasniti kao izbor između alternativa; (A2) sklonosti, uvjerenja i ograničenja aktera glavne su determinante ponašanja; (A3) sklonosti aktera moraju ispunjavati određene uvjete kao što su potpunost i tranzitivnost; i (A4) pojedinci odabiru optimalne alternative s obzirom na svoje sklonosti, uvjerenja i ograničenja. Međutim, primjenom teorije racionalnog izbora u sve većem broju istraživačkih područja sve je jasnija postala empirijska neadekvatnost ovog skupa restriktivnih premisa, što je zagovornike teorije racionalnog izbora potaknulo da usvoje širu verziju koja odbacuje pretpostavku (A4) i dopušta širi raspon sklonosti aktera. Osim ove metateorijske reakcije, neki autori predlažu temeljitiji „popravak“ ove teorije tako što bi se napravio pomak od objašnjenja racionalnog ponašanja aktera temeljenog na maksimizaciji profita. Dva su glavna cilja ovog rada. Prvi je cilj pridonijeti razumijevanju novih koncepata, modela i teorija ljudskog ponašanja (koncept ponašanja slijeđenja pravila, racionalno-heuristički model, Elsterova varijanta teorije racionalnog izbora i modeli ekološke racionalnosti). Drugi je cilj na temelju sveobuhvatne analize sadržaja alternativnih teorijskih koncepcija racionalnoga ljudskog ponašanja dati preporuke za poboljšanje ove teorije.
Chondrosarcoma of the right iliopubic branch incidentally discovered: About a case
Authors: Youness Mokhchani , Abdelhay Rabbah , Abderrafia Rachdi , Jalal Boukhriss , Bouchaib Chafry , Mustapha Boussouga
Published: May 2022

Chondrosarcoma is the most common primary malignant bone tumor after myeloma and osteosarcoma, ranking third. It may be in second place in terms of frequency after osteosarcoma if we consider myeloma as a tumor of bone marrow cells rather than a bone tumor because it is a hematopoietic derivation [1].
Protocol: MHC class I and dengue hemorrhagic fever: a systematic review of HLA-A*24 and HLA-B*44 v1
Authors: C Cook Andrew
Published: May 2022

This project will examine the effect of two MHC class I alleles, HLA-A*24 and HLA-B*44 on dengue hemorrhagic fever susceptibility. A systematic review will be conducted comparing the HLA-A*24 and HLA-B*44 via subgroup analysis and generation of forest plots.
Pain And Mood Assessment in Cancer Patients In A Tertiary Care Hospital v1
Authors: Singh Rajput Pradyuman
Published: May 2022

Cancer Patients often suffer from mixed aetiologies of pain referred to as cancer pain. The study was conducted to assess various cause of pain with it's effect upon the mood of the patient. Pain was measured quantitatively in the study using Visual Analogue Scale(VAS) for Pain and qualitatively using Edmonton Classification System for Cancer Pain (ECS-CP). While Mood for the patients were quantitatively assessed using Visual Analog Mood Scales (VAMS) which incorporates eight various moods generally observed in the population. The study focused upon the occurrence of pain in the cancer population while measuring the mood in the patients and finding correlation between both outcomes.
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Authors: Pivot CBD Gummies Bernard
Published: May 2022

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Authors: Douglas Morris H
Published: May 2022

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Authors: A G
Published: May 2022

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Prognostic value of sFlt-1 and PlGF in the diagnosis of abnormally deep placental invasion
Authors: Godzoeva Alina O. , Zazerskaya Irina E. , Vasilyeva Elena Yu. , Mashchenko Irina A. , Yakovleva Natalia Yu. , Li Olga A.
Published: May 2022

BACKGROUND: Placental adhesive disorder is associated with a high risk of massive bleeding during pregnancy and caesarean delivery. Abnormal trophoblast invasion and pathological hypervascularization detected in these patients may be due to the imbalance of angiogenic factors such as PlGF and sFlt-1, which makes their study an important area of scientific and clinical practice.
AIM: The aim of this study was to evaluate sFlt-1 and PlGF levels in women with placenta accrete spectrum and to compare the data with the results in women with normal pregnancy.
MATERIALS AND METHODS: This case-control study included 71 pregnant women in the third trimester of pregnancy. The main group (n = 32) consisted of patients with prenatally diagnosed placenta previa and abnormally invasive placenta; the control group (n = 39) included patients with normal pregnancy. In the study groups, the levels of sFlt-1 and PlGF were determined, with ultrasound and MRI characteristics evaluated. Statistical analysis was performed using IBM SPSS Statistics 26.0.
RESULTS: Serum sFlt-1 and PlGF levels in the study group differed as compared to controls. In women with placenta accreta spectrum, the median sFlt-1 level was 2886.0 [2175.04127.0] pg/ml vs. control: 1890.0 [1807.02205.0] pg/ml (р 0.001); the median PlGF level was 233.5 [171.4460.5] pg/ml vs. control: 880.9 [746.61210.0] pg/ml (p 0.001). A correlation was revealed between the angiogenic factor levels and the degree of pathological hypervascularization and collaterization according to MRI data. When comparing the probability of abnormally invasive placenta (PAS Grades 2 or 3) and the sFlt-1/PlGF ratio, an ROC curve was obtained with the AUC of 0.74 0.13 (95% CI: 0.481.0; p = 0.021).
CONCLUSIONS: Patients with placental adhesive disorder had increased sFlt-1 levels and decreased PlGF levels compared to patients with normal pregnancy. The above levels correlated with the degree of pathological hypervascularization and collaterization detected by MRI. A prognostic model has been obtained, according to which the threshold value of the sFlt-1/PlGF ratio of 4.22 allows for distinguishing patients with deep placental invasion (PAS Grades 2 or 3).
Modern concepts about the mechanisms of initiation and regulation of labor activity
Authors: Mudrov Victor A.
Published: May 2022

BACKGROUND: The mechanisms of initiation and regulation of labor activity remain insufficiently studied. Currently, there are a significant number of theories that explain the mechanism of onset and regulation of labor, many of which are only of historical interest. Meanwhile, awareness of the true causes and mechanisms of regulation of labor activity will allow preventing not only premature or postmature birth, but also abnormal labor.
AIM: The aim of this study was to discover modern concepts about the mechanisms of initiation and regulation of labor activity.
MATERIALS AND METHODS: We carried out a detailed systematic analysis of modern domestic and foreign literature on the mechanisms of initiation and regulation of labor activity. The study used data hosted by such databases as e-LIBRARY, Scopus, PubMed, MEDLINE, ScienceDirect, and the Cochrane Library (from January 2015 to December 2021).
CONCLUSIONS: According to the literature, the most significant role in the initiation and regulation of labor activity is played by epigenetic mechanisms that reflect the transmission of genetically encoded information in response to a great number of exogenous and endogenous signals varying from patient to patient.
Comparison of patterns of burn severity and clinical characteristics of pediatric patients in a referral burn center: a retrospective analysis
Authors: GÜRBÜZ Kayhan , DEMİR Mete
Published: May 2022

Objective: Burn injuries continue to be an important public health problem worldwide, and childhood burns constitute the most critical burden among these injuries. Although less common, pediatric non-scald burn injuries (NSBIs) generally have a more severe course and cause more significant morbidity and mortality than scald burns (SBs). Many studies only address SBs or NSBIs separately. There are limited studies comparing severity patterns and clinical characteristics of both injuries. It aimed to investigate the severity patterns and clinical characteristics of SBs and NSBIs in hospitalized pediatric patients and compare them with the existing literature.

Methods: A retrospective comparative study design was created among hospitalized pediatric patients. The most frequently observed SBs caused by hot water-tea/hot milk/oil-sauce-soup formed the first group. At the same time, as burn severity was thought to be relatively varied according to initial burn conditions, the NSBIs (fire-flame-related/electrical/contact/chemical-burns) constituted the other group. Data were extracted from the University of Health Sciences- Adana Faculty of Medicine (UHS-AFM) patient files and the electronic registry system.

Results: While SBs constituted 83% of 1715 hospitalized pediatric patients, NSBIs formed only 17% of the study group. Additionally, pediatric non-scald burn injuries had a more severe course in this study. It was determined that NSBIs were responsible for more than two-thirds of mortality compared to SBs. This patient group also required approximately three times more surgical procedures (escharotomy/fasciotomy). Also, the length of hospital stay (LOS) was approximately two times longer than SBs, 23.5±30.5 (1-258), vs. 11.8±9.9 (1-136) (p
The dual role of transforming growth factor-beta signatures in human B viral multistep hepatocarcinogenesis: early and late responsive genes
Authors: Yoo Jeong Eun , Nahm Ji Hae , Kim Young-Joo , Jeon Youngsic , Park Young Nyun
Published: May 2022

Background/Aim: Transforming growth factor-beta (TGF-β) has a dichotomous role, functioning as a tumor suppressor and tumor promoter. TGF-β signatures, explored in mouse hepatocytes, have been reported to predict the clinical outcomes of hepatocellular carcinoma (HCC) patients; HCCs exhibiting early TGF-β signatures showed a better prognosis than those with late TGF-β signatures. The expression status of early and late TGF-β signatures remains unclear in defined lesions of human B-viral multistep hepatocarcinogenesis.Methods: The expression of TGF-β signatures, early and late responsive signatures of TGF-β were investigated and analyzed for their correlation in cirrhosis, low-grade dysplastic nodules (DNs), high-grade DNs, early HCCs and progressed HCCs (pHCCs) by real-time PCR and immunohistochemistry.Results: The expression levels of TGF-β signaling genes (TGFB1, TGFBR1, TGFBR2 and SMAD4) gradually increased with the progression of hepatocarcinogenesis, peaking in pHCCs. The expression of early responsive genes of TGF-β (GADD45B, FBP1, CYP1A2 and CYP3A4) gradually decreased, and that of the late TGF-β signatures (TWIST and SNAI1) significantly increased according to the progression of multistep hepatocarcinogenesis. Furthermore, mRNA levels of TWIST and SNAI1 were well correlated with those of stemness markers, with upregulation of TGF-β signaling, whereas FBP1 expression was inversely correlated with that of stemness markers.Conclusions: The enrichment of the late responsive signatures of TGF-β with induction of stemness is considered to be involved in the progression of the late stage of multistep hepatocarcinogenesis, whereas the early responsive signatures of TGF-β are suggested to have tumor-suppressive roles in precancerous lesions of the early stage of multistep hepatocarcinogenesis.
Iron deficiency in peri-menopausal women: Clinical considerations from an expert consensus
Authors: Malve Vinod , Gandhi Alpesh , Pandit Suchitra , Malhotra Jaideep , Joshi Madhuri , Desai Janaki , Biniwale Parag , Deshmukh Vaishali , Shekhawat Shiva Singh , Sarmah Mamata
Published: May 2022

Iron deficiency (ID) and iron deficiency anaemia (IDA) are usually anticipated to occur during and after pregnancy. Peri-menopausal women are at risk of ID/IDA & warrant attention as the symptoms of ID can be misinterpreted or overlooked. Scientific literatures convey iron deficiency to be considered as a major health problem for perimenopausal women. However, Indian evidence on ‘Iron deficiency in peri-menopausal women’ is scarce.

The aim of this article is to understand the impact of iron deficiency on health of peri-menopausal women in India and to understand its important clinical considerations. Developing an expert consensus towards diagnosis & management of iron deficiency and iron deficiency anaemia in this population is the need of the hour.

A 3-step modified Delphi method was used to build up the consensus. Nine experts representing gynaecology and endocrinology were invited to participate in the panel discussion. Session was being moderated by a senior gynaecologist. In round 1 – the prevalence of iron deficiency anemia in perimenopausal women and risk factors of iron deficiency anemia were discussed. The panel members asked polling questions and each member’s response to the poll question was recorded. The same voting method was used in round 2 and 3, which discussed the diagnosis and management, respectively.

In round 1, round 2 and round 3 statements reached consensus. Consensus was attained for eleven statements representing four different domains: prevalence, risk factors, diagnosis, and treatment.

This consensus guideline will help to standardize care, provide guidance on screening and treatment of iron deficiency anemia in perimenopausal women. This will also assist in clinical decision-making for all healthcare professionals.
Nocuous liver diseases in pregnancies during the covid pandemic
Authors: Priyanka Pentakota Venkata Gowri , Vellanki Janaki
Published: May 2022

Liver disease in pregnancy has always been a challenging issue to an obstetrician. Early identification and aggressive management helps in reducing maternal and foetal morbidity and mortality due to liver diseases in pregnancy. An insight into aetiology of liver diseases in needed for better understanding, to combat its serious effects and reduce the impact of it.

This is an observational analytical study conducted at our hospital and data is collected from labour room admissions of department of obstetrics and gynaecology during March 2020 to May 2021.

Out of 3737 cases admitted to labour room over a period of 15 months, 3638 cases (97.4%) were discharged healthy and 99 deaths (2.6%) were reported including both COVID and non-COVID cases. Out of 3638 cases, morbidity due to liver diseases was observed in 4.5% cases. Out of 99 deaths reported, 40 patients were COVID negative and 59 were COVID positive patients. Deaths due to liver disease were 12 (12.1%) out of all deaths reported. Out of 59 COVID positive deaths, liver disease was also a factor adding to the risk of mortality in 2 cases.

Early diagnosis and aggressive management is cornerstone for decreasing the risk of mortality and morbidity due to liver diseases. A multidisciplinary strategy with close collaboration between intensivists, hepatologists, and obstetricians is required for optimal therapy of liver illness in pregnancy.