bluuebunny/crossref_metadata_2025 huggingface dataset:
Epidemiology, pathogenesis and treatment of urogenital candidiasis in women
Authors:   Donetsk National Medical University, Liman, Aiziatulov R. , Aiziatulova E. ,   Donetsk National Medical University, Liman
Published: April 2022

The objective: to review and analyze thematic publications on the study of epidemiology, pathogenesis of urogenital candidiasis in women. To increase the effectiveness of complex therapy of urogenital candidiasis in women with the use of anti-mycotic drugs of general and local action. Materials and methods. A clinical and laboratory examination of 23 women with urogenital candidiasis aged 21 to 45 years was conducted. Anamnestic data were studied and laboratory research methods were performed. Clinical diagnosis was based on identifying the totality of signs of the disease, which included recurrent pain in the area the appendages, menstrual dysfunction, vaginal discharge, periodic exacerbations of the disease. Results. Patients diagnosed with urogenital candidiasis and candidates are subject to mandatory therapy as potential sources of infection and autoinfection of the urogenital organs. It is necessary to treat sexual partners in a timely manner. An important medical problem is the improvement of treatment methods. It is necessary to pay special attention to urogenital candidal infection in view of the development of severe complications and the effect on the reproductive function of women. Conclusions. Comprehensive treatment of candidal infections of the urogenital tract in women using systemic antifungal drugs (Futsis, Eszol) and local drugs (Сlofan suppositories) is effective, does not cause side effects, and can be widely used by practitioners in practical health care, which will help reduce the number of relapses and more quickly recovery of patients. Key words: urogenital candidiasis, women, etiopathogenesis, clinic, treatment.
Features of treatment in women of postmenopause with intrauterine fluid
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Kuzminа А.
Published: April 2022

The article presents data on the characteristics of the species composition of the microflora of the vagina of postmenopausal women with intrauterine fluid and developed an algorithm for treating this group of patients. The objective: is to study the species composition of the microflora of the vaginal contents in postmenopausal women with intrauterine fluid and based on these data on the development of a treatment algorithm. Materials and methods. The study was conducted for postmenopausal women with intrauterine fluid, who received the contents of the vagina with subsequent referral for microbiological examination. Then the patients were divided into groups to study the effectiveness of complex treatment. In the first group, two-stage treatment was carried out, including etiotropic treatment and the use of vaginal capsules with promestrin. In group II, only etiotropic treatment was performed. Results. As a result of microbiological analysis of the vaginal contents, the patients were divided into 3 groups depending on the microecology of the vagina: with atrophic colpitis 35 (52.2%), with bacterial vaginosis 26 (38.8%), with conditional normocenosis 6 (8.9%). Conducted treatment in groups and evaluation after 1–3–6 months. After 6 months of treatment, in groups I and II, a decrease in UPM by 85% and 47%, respectively, was found, and an increase in the contamination of the vaginal contents with lactobacilli by 87% and 43%, respectively (p<0.05), was also detected. Conclusion. In postmenopausal women with intrauterine fluid, massive microbial contamination of conditionally pathogenic and pathogenic vaginal microflora occurs. Through progressive estrogen deficiency, the unspecific resistance of the vaginal biotope is significantly reduced. The use of intravaginal capsules, which include promestrin, reduces the number of pathogenic and conditionally pathogenic microorganisms in the vagina and thereby reduces the likelihood of developing an ascending infection. Key words: postmenopausal period, intrauterine fluid, microbiological examination of the vagina, promestrin.
Risk factors of development of cysts and benign tumors of ovaries at women of genesial age
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kiev, Boyko A.V. ,   Sumy State University Medical University, MES of Ukraine
Published: April 2022

The objective: to increase forecasting effectiveness of cysts and benign tumors of ovaries at women of genesial age on the basis of establishment of major factors of risk. Materials and methods. Was carried out the retrospective analysis of 500 operational protocols and the histological conclusions regarding compliance of the clinical and pathomorphologic diagnosis to the volume of expeditious treatment. All women were divided into the corresponding subgroups – cysts of ovaries – 284 women and benign tumors of ovaries – 216 patients. All-clinical methods researches were conducted according to the offered card of WHO (2015), including data on the genesial anamnesis, existence of the gynecologic and extragenital diseases, carried-out therapy, the general objective inspection, special gynecologic inspection and laboratory methods of research. Results. In group of high risk on case rate cysts and benign tumors of ovaries treat patients with high frequency benign diseases of uterus cervix(OR=7.32) and body of the womb (OR=6.23), sterility (OR=2.77), inflammatory diseases of organs of small basin (OR=2.39), with disturbances of menstrual cycle (OR=2.3), with high frequency anginas and virus infections (OR=6.55), diseases of thyroid gland (OR=6.4), liver (OR=4.59) and the top respiratory tracts (OR=4.32), not using rational contraception (OR=2.09). Conclusion. The received results needs to be considered when forecasting cysts and benign tumors of ovaries at women of genesial age. Key words: cysts and benign tumors of ovaries, genesial age, risk factors.
Shoulder dystocia: new views on existing problems
Authors:   Ivano-Frankivsk National Medical University, Ukraine, Rymarchuk M.I. , Makarchuk O.M. ,   Ivano-Frankivsk National Medical University, Ukraine, Orishchak І.К. ,   Ivano-Frankivsk National Medical University, Ukraine
Published: April 2022

Although there are known risk factors for shoulder dystocia (such as gestational diabetes and macrosomia), in most cases this complication occurs unexpectedly, leading to situations that can be quite traumatic not only for the mother, but also for the medical workers who are involved in assisting with childbirth. According to reports, a certain number of antenatal and intranatal characteristics are associated with dystocia of the shoulders, but statistical processing showed low prognostic informativeness. Based on the analysis of the literature and on the basis of our own clinical experience, the article suggests methods of manual obstetric care, which are appropriate for difficult removal of the shoulders in childbirth with head presentation of the fetus. Key words: shoulder dystocia, labour, fetus, birth trauma.
Tactics of forecasting of placental dysfunction and fetus arrest of development after auxiliary reproductive technologies
Authors:   Shupyk National Medical Academy of Postgraduate Education, Kiev, Ruban Ya.A.
Published: April 2022

The objective: to develop modern tactics of forecasting of placental dysfunction and a fetus arrest of development after auxiliary reproductive technologies. Materials and methods. The controlled research as a result of which two groups are created was conducted: 1 group was made by 190 patients with one-fetal pregnancy which was caused by application of methods of auxiliary reproductive technologies. The control group was made by 30 patients with one-fetal pregnancy which came independently, they were under immediate observation from early durations of gestation. At these patients profound clinical-laboratory and functional examination according to the uniform standard was conducted. Results. The received results allowed to create complex of rules of the forecast of placental dysfunction and fetus arrest of development at one-fetal pregnancy after auxiliary genesial technologies on the basis of parameters of ultrasonic and gemostaziological researches. Calculation of probability of placental dysfunction and an arrest of development of fetus is carried out individual for every week of pregnancy with 6 on 17 inclusive in the way on the basis of developed in the course of research, informative markers for this term. Conclusion. Application of the developed complex of rules allows to prognosticate effectively placental dysfunction and fetus arrest of development before emergence of its clinical implications and in due time to apply measures of prophylaxis of this complication of pregnancy. The received results grant to us the right to recommend the developed technique in practical health care. Key words: placental dysfunction, fetus arrest of development, forecasting.
Complex rehabilitation therapy of genital endometriosis in women with endometriosis associated infertility
Authors:   Ivano-Frankivsk National Medical University, Ukraine, Orischak I.K. , Makarchuk O.M. ,   Ivano-Frankivsk National Medical University, Ukraine, Rymarchuk M.I. ,   Ivano-Frankivsk National Medical University, Ukraine, Ostrovska O.M. ,   Ivano-Frankivsk National Medical University, Ukraine
Published: April 2022

The most relevant and least investigated questions are the relationships between genital endometriosis and disorders of the fertile function. It is precisely the lack of a clear algorithm for early detection of genital endometriosis and the choice of adequate treatment to further develop these issues, both for improving the quality of life in this category of women and for improving reproductive capacity. The objective: to increase the effectiveness of rehabilitation therapy in patients with genital endometriosis and defection of fertility based on evaluation of individual factors and immunological mechanisms of interaction and optimizing ways to overcome these negative influences. Materials and methods. To achieve this goal, 68 patients with endometriosis associated infertility were examined, which assessed the nature of the hormonal imbalance, violations of individual immune defense units in relation to the level fluctuations of individual tumor markers. In order to evaluate the effectiveness of the proposed program, a group of patients with endometriosis associated infertility was divided into two groups: the main group (38 women) and the comparison group (30 patients). The features of the proposed treatment program were the use after surgical manipulation of complex therapy with the use of progestogens (didrogesterone in contraceptive mode) and the antiproliferative complex: indole-3-carbinol and epigallocatechin-3-galate. Results. Characteristic features of adenomyosis are an increase in this category of patients with levels of LH (2.67 times) and FSH (1.98 times), mainly in the II phase of the menstrual cycle, as well as an increase in estradiol levels, especially in the follicular phase of the menstrual cycle (2, 13 times). In patients with internal endometriosis, in 30.9% of cases (according to ultrasound scan) and in 41.1% of cases (according to histological examination), there are manifestations of hyperplastic processes of endometrium. Increasing the serum CA-125 level (according to our data, 3.1-fold) in women with external genital endometriosis is an effective diagnostic marker to confirm the presence of this pathology. Conclusions. Thus, it should be noted that the proposed rehabilitation therapy for genital endometriosis in the postoperative period is effective in the treatment of pain syndrome and increasing fertility for endometriosis-associated infertility. Key words: genital endometriosis, infertility, hormonal imbalance, tumor markers, rehabilitation therapy.
Histopathological Spectrum of Nephrectomies; a Single Centre Experience of over 14 Years
Authors: Abbas Farhat , Aalmeen Gul , Latief Muzamil , Wani Shahid , Wani Mohsin , Farooq Summyia
Published: April 2022

Nephrectomy is conducted either as an open or a laparoscopic procedure for a variety of clinical indications. These include both neoplastic and non-neoplastic conditions, such as the non-functioning kidney. In many patients the final diagnosis is established on the histopathology of the retrieved kidney. In this study, retrospective analysis of data of last 14 years was studied pertaining to the number and indications of nephrectomy at the present study centre. Demographic and clinical details were assessed. Gross and microscopic histopathological details were recorded. Diagnosis was established on the basis of clinical features and histopathology. A total of 638 total nephrectomy specimens were received. Of these, 280 cases were of neoplastic and 358 of non-neoplastic lesions, with a male-to-female ratio of 1.21:1. The age range varied widely according to clinical manifestations. The age range in the present study was 5–84 years. Patients operated for non-neoplastic disorders were younger (mean age: 38.1 years) than those operated for neoplastic disorders (mean age: 54.4 years). Clear renal cell carcinoma (RCC) was the commonest RCC type (150 patients) followed by papillary RCC (51 cases). Nephrectomy is done due to both benign and malignant clinical indications as observed in this study. The most common indication was chronic pyelonephritis with the non-functioning kidney.
Lactic acid bacteria
Authors: Punia Bangar Sneh , Sharma Nitya , Bhardwaj Aastha , Phimolsiripol Yuthana
Published: April 2022

Mycotoxins produced from Aspergillus, Penicillium, and Fusarium cause food spoilages during handling and storage, owing to immense economic losses and serious human health concerns including immunosuppression and carcinogenic effects. Furthermore, these species are also known to produce mycotoxins. Aflatoxin B1 (AFB1), zearalenone (ZEA), ochratoxin A (OTA), and deoxynivalenol (DON) are the most commonly occurring mycotoxins. The removal of mycotoxins from the contaminated feed using lactic acid bacterias (LABs) has been proposed as a green, inexpensive, safe, and promising mycotoxin decontamination strategy. LABs can control fungal growth by secreting antimicrobial compounds out of their cell wall, thus employing lactobacilli defense mechanisms to destroy bacterial and fungal cells. This article provides systematic review of LABs as bio-green preservative anti-mycotoxin for sustainable food safety.
The Application of Machine Learning Techniques for Predicting Match Results in Team Sport: A Review
Authors: Bunker Rory , Susnjak Teo
Published: April 2022

Predicting the results of matches in sport is a challenging and interesting task. In this paper, we review a selection of studies from 1996 to 2019 that used machine learning for predicting match results in team sport. Considering both invasion sports and striking/fielding sports, we discuss commonly applied machine learning algorithms, as well as common approaches related to data and evaluation. Our study considers accuracies that have been achieved across different sports, and explores whether evidence exists to support the notion that outcomes of some sports may be inherently more difficult to predict. We also uncover common themes of future research directions and propose recommendations for future researchers. Although there remains a lack of benchmark datasets (apart from in soccer), and the differences between sports, datasets and features makes between-study comparisons difficult, as we discuss, it is possible to evaluate accuracy performance in other ways. Artificial Neural Networks were commonly applied in early studies, however, our findings suggest that a range of models should instead be compared. Selecting and engineering an appropriate feature set appears to be more important than having a large number of instances. For feature selection, we see potential for greater inter-disciplinary collaboration between sport performance analysis, a sub-discipline of sport science, and machine learning.
Machine learning techniques to estimate the degree of binder activity of reclaimed asphalt pavement
Authors: Botella Ramon , Lo Presti Davide , Vasconcelos Kamilla , Bernatowicz Kinga , Martínez Adriana H. , Miró Rodrigo , Specht Luciano , Mercado Edith Arámbula , Pires Gustavo Menegusso , Pasquini Emiliano , Ogbo Chibuike , Preti Francesco , Pasetto Marco , del Barco Carrión Ana Jiménez , Roberto Antonio , Orešković Marko , Kuna Kranthi K. , Guduru Gurunath , Martin Amy Epps , Carter Alan , Giancontieri Gaspare , Abed Ahmed , Dave Eshan , Tebaldi Gabrielle
Published: April 2022

This paper describes the development of novel/state-of-art computational framework to accurately predict the degree of binder activity of a reclaimed asphalt pavement sample as a percentage of the indirect tensile strength (ITS) using a reduced number of input variables that are relatively easy to obtain, namely compaction temperature, air voids and ITS. Different machine learning (ML) techniques were applied to obtain the most accurate data representation model. Specifically, three ML techniques were applied: 6th-degree multivariate polynomial regression with regularization, artificial neural network and random forest regression. The three techniques produced models with very similar precision, reporting a mean absolute error ranging from 12.2 to 12.8% of maximum ITS on the test data set. The work presented in this paper is an evolution in terms of data analysis of the results obtained within the interlaboratory tests conducted by Task Group 5 of the RILEM Technical Committee 264 on Reclaimed Asphalt Pavement. Hence, despite it has strong bonds with this framework, this work was developed independently and can be considered as a natural follow-up.
Determination of Mohr–Coulomb failure envelope, mechanical properties and UPV of commercial cement-lime mortar
Authors: Ghimire Amrit , Noor-E-Khuda Sarkar , Ullah Shah Neyamat , Suntharavadivel Thuraichamy
Published: April 2022

Mortar in masonry structures can be subjected to both uniaxial and triaxial loading. Determining the mechanical properties and/or failure criteria of the commonly used mortar is necessary for the structural performance assessment of new and existing masonry buildings using non-destructive testing and/or finite element modelling methods. In this paper, the stress–strain behaviour of a commercially available cement-lime mortar is investigated under uniaxial and triaxial loading. The axial compressive strength, modulus of elasticity, Mohr–Coulomb failure envelopes of the mortar are determined over a range of conditions. Mortar specimens were prepared with a water to cementitious material ratio (w/cm) of 0.6–0.7 and were tested at curing ages of 3, 7, 14, and 28 days, under confining pressures of 0, 100, 250, 500 and 750 kPa. Ultrasonic pulse velocity (UPV) of the specimens were measured before the destructive testing. The results indicate that the influence of curing age and confining pressure on the axial compressive strength of the mortar can be predicted using proposed linear correlations between (i) The confining pressure and the axial compressive strength and (ii) The UPV and the axial compressive strength. From the test results, the strength parameters of the Mohr–Coulomb failure criterion were also determined. It is observed that cohesion is more sensitive to changes in curing age and w/cm than the friction angle, which varied between 32 and 33 degrees.
Bases jurídicas institucionales del proceso de integración económica centroamericana
Authors: Rodríguez Aguilera Carolina Lourdes
Published: April 2022

Esta investigación documental, descriptiva y analítica proponeexplicar las características y los fundamentos jurídicos de la integracióneconómica centroamericana, así como, la organización de su estructurainstitucional. En ese sentido, se examinaron los tratados fundacionales,el derecho comunitario centroamericano, la jurisprudencia de la CorteCentroamericana de Justicia, la teoría de los regímenes internacionales ydeterminados principios del derecho internacional público, con la finalidadde consolidar e ilustrar los objetivos propuestos por la integración económicacentroamericana.
La inadmisión de cuestiones prejudiciales remitidas por instancias administrativas nacionales. A propósito de la sentencia del Tribunal de Justicia de la Unión Europea de 16 de septiembre de 2020, Anesco y otros c/ Comisión Nacional de los Mercados y de la Competencia, recaída en el asunto 462/19)
Authors: Molina del Pozo Carlos Francisco , Puerta Domínguez Enrique Manuel
Published: April 2022

Elemento de flexibilidad a la par que polémico, las apreciaciones pronunciadas por el Tribunal de Justicia de la UE en cuanto a las cuestiones prejudiciales que le son remitidas constituyen expresión de una acentuada independencia judicial. Estos posicionamientos le han llevado en algunos casos a rechazar contestar a las dudas remitidas desde instancias administrativas nacionales. Ante tan inquietantes ejemplos, este estudio propone una metodología científica para comprenderlos mejor, centrándose con carácter especial uno de los más recientemente producidos, y que afecta a precisamente un órgano administrativo español.
Empresas y Derechos Humanos: ¿Presencia en la agenda programática del MERCOSUR?
Authors: Castillo Argañarás Luis Fernando , Vazquez Agustina
Published: April 2022

Los derechos humanos son el marco de efectivo de protección para el desarrollo de la persona; su reconocimiento por parte del Estado implica su garantía para el goce y ejercicio. Sin embargo, resultaría incompleto un análisis que no integre la actividad empresarial.Con el advenimiento de globalización, los avances tecnológicos, las nuevas potencias emergentes y él desdibujo de las fronteras, el mantenimiento del orden internacional presentó nuevos desafíos que fueron respondidos en los distintos niveles de integración.Con especial énfasis, desde los años noventa y al comienzo del milenio, encontramos una preocupación común respecto de las consecuencias de la actividad empresarial en los Derechos Humanos. Preocupación que se tradujo en una creciente agenda temática en distintos organismos internacionales.El rol de las empresas, como típicos actores de la economía doméstica, comenzó a cuestionarse en el contexto de la globalización, y su actuación transfronteriza introdujo nuevos desafíos al marco político y jurídico operante a nivel nacional. Las Naciones Unidas hicieron eco institucional de esta situación a partir del año 2005. Sin embargo, en el MERCOSUR demoró una década más.En este contexto, el presente artículo busca responder al interrogante: ¿qué lugar tiene el tema Empresa y Derechos Humanos en la agenda del MERCOSUR?La respuesta a dicha pregunta se dará mediante el análisis diacrónico de los hitos programáticos del MERCOSUR en materia de Derechos Humanos.
[RETRACTED] Optima Brain MindMax - All-Natural Support For Memory Power! v1
Authors: A H
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[RETRACTED] Aktiv Formulations Delta Sleep: Does It Really Work Or Hoax? v1
Authors: not provided officialdeltasleep
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[RETRACTED] Second Century CBD Review Does Work Benefits Where to Buy 100% Safe Light And Sacam v1
Authors: not provided https://tinyurl.com/SecondCenturyCBD
Published: April 2022

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[RETRACTED] GoKeto Gummies : DON’T HAVE SIDE EFFECTS | EFFECTIVE RESULTS? v1
Authors: A H
Published: April 2022

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It is now a common phenomenon to hear that the breasts of the majority of women and some handful of men have developed cancers.
[RETRACTED] Hard Iron Labs Ultimate Alpha Plus - No Need To consult Doctor?(Doctor Recommended) Made Of All Herbs! v1
Authors: Iron Labs Ultimate Alpha Plus Hard
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Hard Iron Labs Ultimate Alpha Plus Reviews – Do Ultimate Alpha Plus Pills Work or Cheap Scam?
[RETRACTED] Vissential Max BHB Canada - Reviews , Price, Benefits, Side Effects v1
Authors: R Price Alan
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Vissential Max BHB Canada - Reviews , Price, Benefits, Side Effects
[RETRACTED] Stemafil RX Improve Inability To Perform & (Fact Reviews) Help Enhance Stamina! v1
Authors: RX Stemafil
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[RETRACTED] Ikaria Lean Belly Juice Reviews 2022 - The Effective Weight Loss Formula v1
Authors: not provided rohitseo
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Ikaria Lean Belly Juice is a dietary supplement. It is specially designed to help you lose weight. This product is based on the latest scientific research. It is the best way to get rid of the extra fat in the body. Official Website:- https://supplementstree.com/ikaria-lean-belly-juice-reviews/
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Authors: Male Enhancement Omni
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[RETRACTED] Niva CBD Gummies Reviews - Does Niva CBD Gummy Candy Legitimate? v1
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[RETRACTED] Apex Rogue Testosterone Booster v1
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[RETRACTED] Green Otter CBD Gummies Reviews - Does It Really Work? v1
Authors: not provided stephjolsby
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Green Otter CBD Gummies Reviews: are the regular and clinically endorsed CBD-supported gummies. It is the oral sticky intended for individuals that are battling with ongoing problems and inconveniences.
Auditory training through cochlear habilitator (software) in children with cochlear implantation– A pre-post therapy comparison
Authors: Dasgupta Anirban
Published: April 2022

Cochlear Habilitator is an animated hypothetical cochlear pattern right and left with illumination from frequencies 125 Hz to 13000 Hz awareness and saving contours. This programmed has complete battery of training and testing on pure tones from 125 Hz to 10,000 Hz and environmental sounds numbering 79. The present study aimed to see the efficacy of cochlear habilitator in cochlear implant children. A total 10 cochlear implant children under which 4-female and, 6-male participants with in the age range of 3-7 years participated in this study with normal IQ and no history of any health problems. The cochlear habilitator (software) was installed in a laptop connected with two loudspeakers, which are configured with the cochlear habilitator (software) with azimuth angle of 180 degree. The 10 cochlear implant participants were selected based on the subject selection criteria, from the speech and hearing clinic and auditory training was provided for 28 days/sessions. The data was analyzed using SPSS software (version 17.0). T test values shows there is a significant difference in all tasks individually and on overall performance. The mean scores of Post therapy test is higher than the pre-therapy test. Hence cochlear habilitator computer based online software is a useful tool for cochlear implant children’s management in auditory training.
Effect of alternate rapid maxillary expansion and constriction on pharyngeal airway– A case report
Authors: Shetty Sanjana , Shaikh Naazia
Published: April 2022

The Alt-RAMEC protocol was introduced by Liou in the year 2005. It allows for sutural mobilisation by opening and closing the RME screw for 7-9 weeks. Maxillary protraction after the use of Alt-RAMEC (Alternate Rapid Maxillary Expansion and Contraction) protocol is an efficient method for early treatment skeletal Class III malocclusion. This case report shows the results of the using hyrax bonded maxillary expander with Alt-RAMEC protocol to treat a maxillary hypoplasia Class III malocclusion. A 10-year-old patient with skeletal class III malocclusion with anterior as well as unilateral posterior crossbite was treated using this protocol. CBCT scans were taken before and after expansion. These CBCT scans were used for assessing and analyzing the airway tissue changes that have occurred after using Alt-RAMEC protocol. The objective of this case report is to assess airway changes after using Alt-RAMEC protocol.
Keratosis obturans masquerading as cholesteatoma- A case report
Authors: Dominic Snekha P , Patial Agnieesh , Shah Ruchi
Published: April 2022

Keratosis obturans is a condition of the external auditory canal, characterised by the stratified accumulation of keratin plugs within the external auditory canal. The progressive accumulation of keratin debris can lead to the gentle erosion and widening of the canal eventually. Whereas, Cholesteatoma also known as active squamosal chronic suppurative otitis media (CSOM) is a benign keratinizing epithelialized cystic structure found in the middle ear and mastoid. It can cause destruction of the local structures – ossicular chain and otic capsule, thereby leading to complications such as hearing loss, vestibular dysfunction, facial paralysis and intracranial disease or infection. Both these entities may present with severe otalgia and conductive hearing loss with radiological evidence of bony erosions. The similarity in clinical presentation can cause confusion between these two conditions. We present a case of keratosis obturans that was misdiagnosed as active squamosal CSOM. The case was diagnosed and managed by microscope guided examination and exploration under general anaesthesia.
Devil’s bite in an adult woman: Unheeded & overlooked
Authors: Basavannaiah Sphoorthi
Published: April 2022

Cleft lip and cleft palate are birth defects that occur when a baby’s lip or mouth does not form properly during pregnancy. Together, these birth defects are commonly called “Oro-facial clefts”. Cleft palate alone can often have problems with feed, speech & hearing and problems with teeth development. The causes of these clefts among most infants are unknown. Cleft lip and cleft palate in a child are thought to be caused by a combination of genes and other factors during their gestational development.
Antimicrobial activities of microbial essential fatty acid against foodborne pathogenic bacteria
Authors: Mirbagheri Firoozabad1 Maryam Sadat , Mohammadi Nasr Mina
Published: April 2022

Background and Objectives: Human health and development have been related to dietary intake of essential fatty acids (omega 3, 6 and 9) and important for brain development, immune system function, and blood pressure regulation. Microbial essential oils are more natural and safer alternatives to synthetic preservatives. These oils have been demonstrated to have antibacterial activity within food systems and may be ideal additives to food formulations. Zygomycete fungi are well-known as good candidate for production of essential oils.
Materials and Methods: Essential oils of fungi Mucor rouxii, Mucor circinelloides and Cuninghamella echinulata were extracted and fatty acids were analyzed by GC, for the first, antimicrobial activity of the fungi essential oils against foodborne pathogenic bacteria E. coli, S. aureus, B. cereus, B. subtilis, and S. enterica was examined by disc diffusion and well diffusion methods and the minimal inhibitory concentrations (MIC) of oils were determined by microtiter plate.
Results: The fungi oils were exhibited the stron g antibacterial effect against Gram-positive bacteria, B. cereus, S. aureus and B. subtilis higher than Gram-negative and commercial oleic acid and linoleic acid. The MIC of the fungi oil extracts was 0.25 mg/ml for B. cereus and B. subtilis and 0.5 mg/ml about S. aureus. This research demonstrated microbial essential oils may be suitable for their antimicrobial properties in food.
Conclusion: Microbial essential oil with good antibacterial activity could also be used in selected cases like foodborne disease.
Iodine induces toxicity against Candida albicans and Candida glabrata through oxidative stress
Authors: Cuellar-Rufino Sergio , Arroyo-Xochihua Omar , Salazar-Luna Aranthxa , Arroyo-Helguera Omar
Published: April 2022

Background and Objectives: Candida species are antifungal-resistant opportunistic infections that spread through contami- nated medical staff hands and hospital surfaces creating a nosocomial infection risk. Iodine´s antibacterial properties are well established; however, its antifungal properties remain unknown. The objective of this study was to investigate the antifungal effects of lugol on cell viability and oxidative stress on Candida albicans and Candida glabrata strains.
Materials and Methods: MTT reduction test and sensitivity growth assay were used to determine viability and minimal inhibitory concentration, colorimetric tests were used to analyzing lipoperoxidation and antioxidant status in C. albicans, parental C. glabrata, C. glabrata lacking catalase gene (cta1) and superoxide dismutase 1 and 2 double mutants (sod1∆ sod2∆) strains exposure to lugol were used.
Results: In both C. albicans and C. glabrata wild types lugol treatment decreased cellular viability in a dose-dependent man- ner at 30 mm. The cytotoxic lugol effect was characterized by the increase of oxidative stress and the reduction of superoxide dismutase and catalase enzyme activities. C. glabrata strains lacking catalase (cta1) and superoxide dismutase 1 and 2 double mutants (sod1∆ sod2∆) were less resistant to lugol than parental C. glabrata strains.
Conclusion: In Candida strains iodine lugol solution has antifungal properties, producing cytotoxicity and oxidative stress. Superoxide dismutase 1 and 2 activities are involved in resistance of Candida to iodine.
Prospects for Developing Modern High-Vacuum Mechanical Pumps
Authors: Ochkov A.A.
Published: April 2022

High-vacuum mechanical pumps are widely used in various fields of science and technology for research and industrial applications. Modern high-vacuum mechanical pumps include molecular vacuum pumps, turbomolecular vacuum pumps and hybrid turbomolecular vacuum pumps, i.e., designs that represent a turbomolecular vacuum pump with one or more additional molecular stages. There are also a number of experimental and theoretical developments that propose combinations of different types of high-vacuum pumps in which, as a rule, on the suction side the main pumping is carried out by an axial turbomolecular stage. These schemes belong to the class of modern high-vacuum mechanical pumps. The paper examines the designs and analyzes scientific studies of modern high-vacuum mechanical pumps. Relying on this overview, we found the unsolved problems of designing and mathematical modeling of high-vacuum mechanical pumps working processes, which could give further prospects for vacuum technology development
Methodology for Justifying the Structure of a Combined Spacecraft System
Authors: Vlasov S.A. , Kulvits V.A. , Kovalenko A.Yu. , Mosin D.A.
Published: April 2022

The analysis of functioning of the Earth remote sensing spacecraft systems of the domestic orbital constellation is performed. The approach to joint application of currently operating and newly launched spacecraft, which will improve the performance of the domestic Earth remote sensing orbital constellation at the stages of deployment, buildup and replenishment, is proposed. Problems of designing spacecraft systems on different orbits, differing by position in space, orbital period and observation characteristics are investigated. A technique for justifying the structure of a combined spacecraft system using the proposed indicator has been developed. The use of the given technique allows one to analyze, justify the orbital structures and improve the performance indicators of a system of Earth remote sensing combined spacecraft. The dependences of the performance indicator of the spacecraft system functioning for different variants of the orbital structures of combined spacecraft systems upon the orbital planes position were obtained. For example, the uniformity of review intervals is achieved by alignment of observation conditions at upper and lower latitudes, which can be determined by solving a geometric problem on a sphere. The methodology is recommended to be used at the stages of deployment and buildup of domestic orbital constellation taking into account newly launched spacecraft, as well as at the stage of deployment and operation of incomplete spacecraft systems
A Wedge witha Heat-Resistant Lining in a High-Speed Airflow: Comparative Estimate of the Thermal State
Authors: Aliev Az.A. , Zimin V.N. , Tovstonog V.A. , Tomak V.I.
Published: April 2022

The efficiency and maximum height, speed and duration characteristics of the flight path of high-speed atmospheric aircraft are largely determined by the temperature regime of the most heat-stressed structural elements, suchas the edges of airframe airfoils. Their active thermal protection systems contribute to solving a number of complex scientific and technical problems, the most promising and simple solution being heat-resistant inorganic materials of the oxide class. However, their use for the structural design of the edge as a monolithic structural element is difficult both in terms of technology and strength characteristics, especially in the heat shock mode. In this regard, a promising solution is an edge in the form of a core made of heat-resistant and heat-conducting materials with a high-temperature oxide ceramic lining, which protects from the environmental oxidative effects and provides the permissible temperature regime of the core due to thermal resistance determined by the thickness of the lining. The study examines the temperature conditions of the wedge-shaped edge with a heat-conducting core and a heat-resistant ceramic lining. When choosing materials for the core and lining, it is important to preliminary calculate and estimate the parameters of the edge performance, taking into account the data on the thermophysical and physicomechanical properties of the materials. The study comparatively analyzes the thermal state of a prefabricated wedge with a heat-conducting core made of hafnium boride, which is an advanced heat-resistant material, and molybdenum and nickel, which are more technological and cheap metal materials, with a lining of oxide heat-resistant ceramics
Chemical Nickel Plating Technology for Product Surfaces
Authors: Skryabin V.A. , Zverovshchikov A.E.
Published: April 2022

When studying how a coating influences the wear resistance of details made of aluminum alloys in production conditions, we conducted a multifactorial experiment. The research has been carried out on the application of nickel-phosphorus coating on the surface of parts made of aluminum alloys, as well as the prefinishing treatment under coating. The parameters influencing the rate of nickel-phosphorus alloy deposition and modes of part surface treatment under coating are selected. Experiment planning was carried out, which made it possible to develop optimal modes of deposition and coating composition for obtaining high quality parameters of its surface: roughness and wear-resistance. It has been established that increasing the concentration of hypophosphite (sodium salt of alkaline metal and hypophosphorous acid) increases the coating formation rate. Experimental studies on wear resistance of nickel-phosphorus coated and uncoated samples have been conducted. The study shows that nickel-phosphorus coated samples provide higher wear resistance under friction conditions in comparison with uncoated samples, and assumes that the uniformity of heterogeneous coating consisting of nickel and phosphorus is due to the uniform fine crystalline structure consisting of regular shape particles (faceted or rounded). The basic principles of chemical coating technology and mechanical engineering technology are used
Resistance evaluation of oat genotypes to stem rust (Puccinia graminis f. sp. avenae)
Authors: Huerta-Espino Julio , Ramírez-Ramírez Erika Evelin , Leyva-Mir Santos Gerardo , Villaseñor-Mir Héctor Eduardo , Santa-Rosa René Hortelano , Martínez-Cruz Eliel , Rodríguez-García María Florencia
Published: April 2022

The resistance in seedling and adult plant of 13 varieties and 37 lines of oats against stem rust caused by Puccinia graminis f. sp. avenae was evaluated. TNQ and TFQ races and isolates AMEX18.21.1.1 and AMEX18.18.1.1 for seedling evaluation; and AMEX18.18.1.1 isolate in adult plants were used. The Diamante, Menonita, Karma and Turquesa varieties were resistant in seedling to the TFQ race, but susceptible to TNQ and the isolates AMEX18.21.1.1 and AMEX18.18.1.1, the other varieties were susceptible to the two races and isolates. All varieties were susceptible to isolate AMEX18.18.1.1, in seedling, but in adult plants these were classified as susceptible, intermediate and only Teporaca was resistant. The 37 lines were classified into 17 groups by final severity and sister lines. Genotypes 25, 28, 34, 39 and 48 were seedling resistant to AMEX18.18.1.1, and the rest were susceptible. In the field all the lines were resistant and only genotype 19 of group 14, reached a 20% infection. From its response in seedlings and in adult plants of the advanced lines, it is inferred that resistance is conditioned by adult plant genes.
Comparative Study of Different Fat Replacer in the Development of Low Fat Chevon Patties
Authors: Nayak N.K. , Pathak V.
Published: April 2022

Background: Since last decade demand for healthy and nutritious foods with additional health promoting functions has continuously been increased. Although meat and meat products traditionally have higher levels of fat therefore these products offer the good opportunity to develop low fat functional meat products. Fat replacements should contribute a minimum of calories to a product and should not be detrimental to organoleptic qualities. Therefore, the current study was undertaken to assess suitability of various functional ingredients for the development of low fat chevon patties. Methods: Pre-weighed quantity of minced chevon meat, along with other ingredients were added and chopped in a bowl chopper till desired consistency of the emulsion was achieved. Weighed quantity of emulsion was taken and molded in to patties shape and cooked at specified time and temperature combination. Three selected variant i.e carrageenan (CG), poppy seed (PS) and sago flour (SF) were used for the study. All samples were processed for physicochemical, mineral estimation, instrumental texture, color and sensory analysis. Result: Significantly (P less than 0.05) lower fat and cholesterol contents and higher moisture and fat retention were observed in carrageenan incorporated chevon patties. However, calcium, iron, manganese and zinc contents were significantly (P less than 0.05) higher in poppy seed incorporated low fat chevon patties. The instrumental textural and color profile were also differ significantly (P less than 0.05). The flavor score was significantly (P less than 0.05) higher for chevon patties with carrageenan. The carrageenan added low fat chevon patties (CG) were found superior and widely acceptable among the sensory panelists. Hence, 0.6% carrageenan added chevon patties were selected to develop low fat chevon patties.
“EMD-SVR” Hybrid Machine Learning Model and its Application in Agricultural Price Forecasting
Authors: Das Pankaj , Jha Girish Kumar , Lama Achal , . Bharti
Published: April 2022

Timely and accurate price forecasting is one of challenges in agriculture. It helps both producer and consumer to make the efficient plan. The inherent nonstationarity and nonlinearity in price data makes problem in forecasting. A single forecasting model may not be able to tackle nonstationarity and nonlinearity, simultaneously. With this context, a nonlinear hybrid model called EMD-SVR has been proposed to deal the problem. The empirical mode decomposition (EMD) deals with nonstationarity by decomposing price data into a finite and small number of subsets. Further, these decomposed subsets are forecasted using Support Vector Regression (SVR) model and aggregated to make final forecast. The performance of the proposed hybrid model are evaluated in monthly price index of chili. The empirical results indicated the superiority of the EMD-SVR model.
Effect of Yeast Bio-fertilizer on Lettuce Growth and Productivity
Authors: Natsheh Basel , Masoud Wafa , Abu-Khalaf Nawaf
Published: April 2022

Background: Synthetic fertilizers and pesticides are widely used, with detrimental repercussions for soil microbial biodiversity and environmental contamination. The use of microorganisms as bio-fertilizers has been recommended as an alternative agricultural strategy. Due to their potential to safely boost plant development, yeasts can be used to make high-quality bio-fertilizers and biopesticides in a variety of ways. As a result, substantial yeast research could be promising and could provide an environmentally acceptable solution to the increasing agricultural output that would be necessary as the world’s population grows. Methods: The study was conducted to investigate the effect of different yeast concentrations on lettuce crop production and quality. The experiment consisted of four treatments (1%, 3%, 5% and 7% w/v yeast). The measurements included chlorophyll content, plant length (cm) and plant-wet weight for shoot and root (g). The design of the experiment was a complete factorial design with five replicates for each treatment. Three doses of each yeast solution, i.e. 1%-7% w/v, were added to soil after 7, 25 and 40 days from cultivation. The plants were harvested after 52 days. Result: In the current study, it was found that the highest chlorophyll content with a value of 44.6 was obtained at 3% w/v of yeast concentration followed by 1% w/v (39.7), 5% w/v (44.3) and 7% w/v (41), respectively. The average maximum length of plants after 52 days was 26.6 cm at 3% w/v and 26.13 cm at 5% (w/v) of yeast concentrations. The other treatments gave lower values, i.e. 24.4 cm, 22.2 cm and 19.1 cm for 1% w/v, 7% w/v and control, respectively,. The values have the same trend during the experiment time at the three stages (7, 25 and 40) days from cultivation. The optimum plant wet weight for shoot and root with 3% w/v yeast concentration were 212.2 and 33.9 g, respectively. At 5% w/v of yeast concentration, the wet weight for shoot and root were 200.1 g and 30.7 g followed by 7% w/v (196.2 g and 25.6 g) and 1% w/v (171.2 g and 26.4 g).