bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Network Simulation of Bawang Ada’ (Eleutherine americana Merr.) from Dayak Lundayeh in North Kalimantan Tackle various Viral Infection Targeting Key Protein
Authors: Kharisma Viol Dhea , Listiyani Priscilla , Ali Murtadlo Ahmad Affan , Putra Pradana Rizal Adistya , Ansori ANM , Patera Nugraha Alexander , Rollando Rollando , Kuncoroningrat Susilo Raden Joko , Hayaza Suhailah , Olegovna Budagova Sofya , Vadimovich Nadvodnyk Gregory , Gennadievich Lebedev Ivan , Nadirovna Khalibekova Zaira , Vladimirovich Rzhepakovsky Igor , Rebezov Maksim , Jakhmola Vikash , Purnobasuki Hery , Kusuma Wahyuni Dwi
Published: July 2024

Viral replication inhibition strategies are needed to prevent pandemics through the latest therapeutic agent designs. A viral infection occurring over a wide area is called a pandemic. The strategy of inhibiting virus replication is used to tackle the pandemic Viruses can trigger negative regulation of apoptosis in host cells for viral survival. Apoptosis can reduce viral load and inhibit viral replication. Several types of viruses can evade the immune response through upregulation of various anti-apoptotic proteins, which allows this research to explore specific types of anti-apoptotic proteins in host cells for the design of candidate therapeutic agents.Medicinal plants from the Dayak Lundayeh tribe in North Kalimantan have potential for health, the antiviral potential of these plants has not been identified. This study aims to reveal the potential of the bioactive compounds from Bawang Ada' as antivirals with a molecular mechanism through apoptosis with an in silico approach.The in silico method used in this study consisted of ligand preparation, druglikeness analysis, pathway prediction, docking, and molecular interaction.Bawang Ada' acts as the best antiviral candidate through the activity of Erythrolaccin and Isoeleutherin compounds in inhibiting antiapoptotic proteins consisting of GSK3B and AKT1. We recommend the binding sites Val70, Leu132, Ile62, Leu188, Asp200, and Cys199 (GSK3B) and Leu210, Leu264, Tyr272, Asp292, Trp80, Lys 268, Val270, and Ser205 (AKT1) for further research as antiviral target development.
Identification and Analysis of Ardisia humilis as Potential Antihyperlipidemic by Network Pharmacology Followed by Molecular Docking
Authors: Puspita Rini Tri Diana , Sangande Frangky , Agustini Kurnia , Bahtiar Anton
Published: July 2024

Objective: Hyperlipidemia is increasing lipids in a body that are risk factors for cardiovascular disease that increased last over 30 years. Natural products have a large portion as pharmacological agents, particularly in disease therapies. The pharmacological activity of natural product remedies has been thoroughly screened using high approaches in drug discovery. Lampeni, also known as Ardisia humilis Vahl, is utilized for various illnesses such as vertigo, rheumatism, and skin ulcers, and as a stimulant, carminative, andantidiarrheall.Previous studies have shown that feeding Swiss albino rats alcohol extract at 200mg/KgBW could decrease LDL, triglycerides, total cholesterol, and VLDL and increase HDL. Method: This study aimed to predict Lampenileaf's network pharmacology as a potential for hyperlipidemiausing multiple ethnobotanical databases and software. This research was cond.This is in silico. Results: The result of Lampeni leaf is almost all bioactive compounds targeted hyperlipidemia-associated genes.Compounds with the highest potential of Hyperlipidemia are Ardisinol II, Bilobol, ArdisiphenolB, Maesaquinone, Beta amiryn, and Embelin. IL6, HSP90AA1, EGFR, MAPK3, SRC, PPARG, and STAT3 had the best value and became the gene doth the Lampeni leaf compound.These targets are tightly associated with inflammatory and proliferation processes, which explain the possible explaining Lampeni leaf in attenuating hyperlipidemic symptoms.Further study is needed to validate the result other than by molecular docking method, such as molecular dynamics, in vitro, or in vivo studies.
Mikroprzedsiębiorczość na obszarach wiejskich
Authors: Kłodziński Marek
Published: July 2024

Mikroprzedsiębiorstwa wiejskie ze względu na małą liczbę kredytów i niezbyt ambitne plany inwestycyjne okazały się dość odporne na wielkie zawirowania związane z kryzysem. Rola mikrofirm w gospodarce kraju jest bardzo duża, wytwarzają one 30,1% PKB i zatrudniają 40,6% ogółu pracowników sektora przedsiębiorstw w Polsce. Mikrofirmy stanowią aż 94,8% ogólnej liczby przedsiębiorstw. Mimo że ich kondycja finansowa jest nie najgorsza w porównaniu z firmami zatrudniającymi znacznie większą liczbę pracowników, to wiele sygnałów wskazuje także na ich rozliczne słabości, które są szczególnie charakterystyczne dla przedsiębiorczości wiejskiej. Przezwyciężenie barier rozwoju firm na terenach wiejskich wymaga nieco odmiennego podejścia, ponieważ działają one w znacznie trudniejszych warunkach niż przedsiębiorcy w dużych miastach. Powstanie sieci Natura 2000 dodatkowo komplikuje rozwój przedsiębiorczości na terenach wiejskich, co wymaga zakrojonej na dużą skalę akcji wyjaśniającej i propagującej dopuszczalny zakres rozwoju firm na terenach chronionych, a być może także utworzenie specjalnego funduszu środowiskowego rekompensującego straty za tak zwane utracone korzyści nie tylko urzędom gminnym, ale także przedsiębiorcom.
Rolnictwo w sieci – alternatywne sieci produkcji i dystrybucji żywności
Authors: Knieć Wojciech , Goszczyński Wojciech
Published: July 2024

Celem opracowania jest wstępna analiza naukowej oraz praktycznej przydatności popularnej koncepcji alternatywnych sieci produkcji i dystrybucji żywności (Alternative Agro-Food Networks). W artykule poruszone zostały problemy dotyczące powiązania zmian w rolnictwie z rozwojem społeczności lokalnych oraz szans i ograniczeń związanych z alternatywnymi formami produkcji. Zostały też zaprezentowane pierwsze doświadczenia we wdrażaniu tej sieci w Polsce.
Kultura zaufania czy nieufności? O społecznym zaufaniu mieszkańców lokalnych społeczności
Authors: Mularska-Kucharek Monika
Published: July 2024

Przedmiotem rozważań niniejszego artykułu jest zaufanie społeczne badane w trzech wymiarach: wertykalnym (wobec różnego rodzaju instytucji) oraz dwóch horyzontalnych – prywatnym i uogólnionym. Głównym celem artykułu jest natomiast próba odpowiedzi na pytanie o poziom zaufania społecznego dorosłych mieszkańców gmin wiejskich województwa łódzkiego. Analiza dotyczy diagnozy zaufania społecznego badanej społeczności oraz ustalenia korelatów trzeciego w wyżej wymienionych rodzajów zaufania, tj. uogólnionego zaufania okazywanego innym ludziom.
Penerapan Media SMAB (Smart Box) pada Pembelajaran Matematika Siswa Kelas IV SD Negeri 1 Air Deras
Authors: Damayanti Zulita , Pandra Viktor , Mandasari Novianti
Published: July 2024

Penelitian ini bertujuan untuk mengetahui ketuntasan hasil belajar matematika siswa kelas IV SD Negeri 1 Air Deras. Metode penelitian yang digunakan berbentuk eksperimen. Populasinya adalah seluruh siswa kelas IV SD 1 Air Deras dan sekaligus sampel penelitian yang berjumlah 19 Siswa. Pengumpulan data dilakukan dengan teknik sampling jenuh. Data yang terkumpul dianalisis menggunakan tes. Berdasarkan hasil analisis data dengan taraf kepercayaan a = 5% dan dk = 18 menunjukkan besar Zhitung = 4,67 dan Ztabel = 1,64 (Zhitung > Ztabel). Nilai rata-rata tes akhir siswa sebesar 80,36 serta persentase siswa yang tuntas sebanyak 17 siswa (89,48%). Dengan demikian dapat disimpulkan bahwa proses pembelajaran menggunakan media smart box bisa berjalan dengan sangat baik karena bisa dilihat dari hasil belajar Matematika siswa kelas IV SD Negeri 1 Air Deras setelah penerapan media Smart Box secara signifikan tuntas.
Systematic Literature Review (SLR): Islamisasi Sains dalam Perspektif Filsafat Pendidikan
Authors: Aulia Mizar , Usiono Usiono
Published: July 2024

Islamisasi sains merupakan upaya mengembalikan ilmu pengetahuan yang telah dipengaruhi oleh barat menjadi ilmu pengetahuan yang sarat akan nilai-nilai Islam. Tujuan utama adanya islamisasi sains adalah mengeluarkan umat Islam dari belenggu pemikiran barat yang selalu mendikotomikan agama dan ilmu pengetahuan. Melalui dikotomi yang dilakukan barat tersebut menyebabkan terjadinya pembedaan antara ilmu agama dengan disiplin ilmu lainnya, padahal dalam Islam keseluruhan ilmu pengetahuan adalah satu kesatuan yang bersumber dari Al-Qur’an. Penelitian ini menggunakan metode penelitian SLR (Systematic Literature Review) yang bersumber dari artikel yang telah dipublikasikan pada tahun 2019 sampai dengan tahun 2023 sebanyak 10 artikel jurnal yang diperoleh dari google scholar terkait Islamisasi sains atau ilmu pengetahuan. Hasil penelitian ini menemukan bahwa gagasan Islamisasi sains dilatarbelakangi karena kekhawatiran pemikir-pemikir muslim terhadap kerusakan dan kekeliruan ilmu pengetahuan yang digunakan manusia karena pengaruh sekularisasi barat terhadap ilmu pengetahuan. Tokoh-tokoh muslim yang cukup kritis dan konsisten dalam menggaungkan konsep Islamisasi sains adalah Ismail Raji al-Faruqi dan Syed Muhammad Naquib al-Attas. Tujuan islamisasi sains adalah mengembalikan kesucian ilmu pengetahuan dengan nilai-nilai Islam. Implikasi islamisasi sains bagi filsafat pendidikan Islam adalah pelembagaan dua sistem ilmu yakni ilmu agama dan ilmu umum lewat integrasi keilmuan.
Pengaruh Minat Belajar dan Kemampuan Berpikir Kritis terhadap Kompetensi Kerja melalui Self-Efficacy sebagai Mediasi bagi Siswa SMK Keahlian Kuliner
Authors: Rini Setiyo , Sutiadiningsih Any , Joko Joko
Published: July 2024

Tujuan Penelitian ini adalah untuk mendeskripsikan (1) pengaruh minat belajar terhadap kompetensi kerja siswa; (2) kemampuan berpikir kritis kepada kompetensi kerja siswa; (3) Self-efficacy terhadap kompetensi kerja siswa; (4) minat belajar terhadap kompetensi kerja yang dimediasi oleh dan Self-efficacy; (5) kemampuan berpikir kritis terhadap kompetensi kerja yang dimediasi oleh Self-efficacy pada siswa kelas XI Jurusan Kuliner SMK Di wilayah Kediri. Pendekatan penelitian adalah kuantitatif dengan rancangan penelitian survey menggunakan angket. Jumlah Sampel 179 siswa Program kuliner kelas XI SMK Di wilayah Kediri. Analisis data menggunakan SEM-PLS. Hasil temuan pada penelitian ini adalah: (1) ada pengaruh minat belajar terhadap kompetensi kerja siswa dengan dengan nilai signifikansi 0,000 < 0,05, (2) kemampuan berpikir kritis terhadap kompetensi kerja siswa memiliki pengaruh dengan nilai signifikansi 0,000 < 0,05, (3) terdapat pengaruh self-efficacy terhadap kompetensi kerja siswa dengan nilai signifikansi 0,000 < 0,05, (4) minat belajar terhadap kompetensi kerja yang dimediasi oleh dan self-efficacy tidak memiliki pengaruh dengan nilai signifikansi 0,316 > 0,05 dan kemampuan berpikir kritis terhadap kompetensi kerja yang dimediasi oleh self-efficacy memiliki pengaruh dengan nilai signifikansi 0,000 < 0,05 pada siswa kelas XI Jurusan Kuliner SMK Di wilayah Kediri.
Bubbles in China’s Housing Market
Authors: Shang Jiayu , Ong Sheue-Li
Published: July 2024

The housing market in China has been booming since the housing reform in the 1990s. This has raised concerns around the world that the Chinese housing market is a bubble about to burst, particularly after the 2008 Global Financial Crisis which was triggered by a housing bubble burst. After implementing a number of empirical methods with panel data that cover 30 provinces/municipalities from 2002 to 2020, the results show that house price is cointegrated with the relevant market fundamentals in the long run. At the same time, short-run fluctuations and deviations in house prices from market fundamentals also exist. The estimation results identify two distinct features of the housing bubble. The first feature is that there are two obvious bubble periods. The first bubble period is from 2009 to 2013 and the second bubble period is from 2017 to 2020. The second feature is that the size of the bubble varies among the different regions. The largest bubble occurred in Hainan province in 2010, which is as large as 40% of the equilibrium value determined by market fundamentals. As for the national average, the largest bubble is also recorded in 2010, the size of which is 11% of the equilibrium value determined by market fundamentals.
The Impact of Commitment on Pending Home Sales in Entrapping Situations
Authors: Lee Jin Man , Seah Kiat Ying , Shilling James
Published: July 2024

This paper examines the decision-making processes of home buyers during the Global Financial Crisis, with a specific focus on passive coping mechanisms and the role of risk aversion. The study investigates how risk aversion influences the behavior of home buyers and highlights the disparities between high-income and low-income buyers. The findings reveal that high-income home buyers exhibit a risk aversion parameter that ranges from 1.74 to 1.99, while low-income home buyers have a parameter that ranges from 0.60 to 0.62, thus indicating different levels of risk tolerance and decision-making patterns among the income groups. These findings suggest that low-income home buyers are more likely to endure unfavorable situations or avoid making changes in periods of declining house prices than high-income home buyers. This behavior aligns with the concept of passive coping, where low-income home buyers choose to endure unfavorable situations rather than making changes because they fear the negative outcomes that may arise from taking a different course of action. They might worry that if they abandon the contract, they will miss out on the opportunity to own a home, live in a desirable neighborhood, or secure a specific property. This fear of potential losses leads them to choose passive coping, where they endure the current situation rather than making changes that could involve risks or uncertainties.
Move, Stay, or Pay: The Impact of Land Prices on Migration Balances in Germany
Authors: Götzelmann Lukas Felix , Mager Ferdinand , Hennig Kerstin
Published: July 2024

This paper examines the effects of housing costs on net migration in Germany, a country with a polycentric structure. We apply a panel data estimation framework with a large array of unit, time, and regional fixed effects to close to 400 individual counties for the period of 2002 to 2018. Our findings suggest a strong and negative relation between residential land prices and net migration. We conclude that higher land prices can largely offset the additional amenities factored into housing costs and hence cause negative effects on migration. We show that our results are robust to various control specifications, including the addition of variables such as income, education, and age structure, and the use of time lags.
Retained Earnings and Dividends in Real Estate Sector in Egypt
Authors: Said Mohamed Gabr Noha , Hamed Abd Elkhaliq Mohamed Rawan
Published: July 2024

This study examines the trade-off between retained earnings (REs) and dividends in the Egyptian context to determine whether REs affect dividend policy and payout. Additionally, the study examines how the life cycle of a company influences the aforementioned relationships. The results of a multiple regression analysis indicate that REs are positively and significantly related to dividend policy and payout. However, when the company life cycle is introduced as a moderator, the results suggest a significantly negative relationship. Furthermore, a confirmatory test reveals that lagged REs influence dividend policy and payout. These findings carry significant implications for various stakeholders in Egypt. To the best of the knowledge of the authors, no study has investigated the causal relationship between REs and dividends in the Egyptian real estate context.
Comparative World Literature: Making a Case for Re/Translation
Authors: D'haen Theo
Published: July 2024

Translation has been a major bone of contention in comparative literature studies. For the longest time it was looked down upon by bona fide comparatists, who insisted on studying literary works in the original. World literature scholars, on the contrary, have from the beginning acknowledged that, given the multiplicity of the world’s languages and their literatures, it was inevitable that one resort to translation to access all but a handful of literatures. The final decades of the 20th century saw the rise of translation studies. Adopting insights and methods from descriptive translation studies might help bridge any putative gap between comparative and world literature studies, also when it comes to transcultural studies.
Navigating organizational excellence: a comparative study and roadmap for streamlining defense infrastructure organizational model of Georgia
Authors: OKROMTCHEDLISHVILI Ivan
Published: July 2024

In the face of evolving geopolitical dynamics and increasing security challenges, the efficacy of a nation’s defense infrastructure is pivotal. This article conducts a comprehensive exploration of defense infrastructure organizational models, centering on the United Kingdom, France, Germany, Australia, and Latvia. Through a meticulous comparative analysis, the study delves into organizational structures, international operations, responsibilities, and strategic focuses of these nations’ defense infrastructure entities. The goal is to glean insights applicable to Georgia’s unique context, identifying key differences and commonalities to formulate a strategic roadmap for enhancing its defense infrastructure capabilities. The article examines each country’s defense infrastructure model, highlighting distinctive features in organizational structure, international operations, responsibilities, and strategic focus. Drawing upon these insights, the study proposes tailored recommendations for Georgia, spanning organizational structure, international operations, responsibilities and focus, modernization and strategy, and integration of departmental efforts. Key entities within Georgia’s defense infrastructure organizational model, such as the Department of Defense Sustainability, the J-4 Logistics Planning Department, and the Command for Logistics Support of the Troops, are illuminated to underscore their pivotal roles in fortifying the country’s defense capabilities. Concluding with the identification of key areas for improvement in Georgia’s defense infrastructure organization, the article outlines recommendations encompassing organizational structure, international operations, responsibilities and focus, modernization and strategy, and integration of departmental efforts. By aligning Georgia’s defense infrastructure with international best practices, the nation can enhance security, contribute to regional stability, and actively participate in global security efforts. In essence, this article serves as a strategic guide for Georgia, offering a roadmap to fortify its defense infrastructure in a rapidly changing world. Through a synthesis of global insights and tailored recommendations, Georgia can position itself as a resilient and adaptable force, safeguarding national interests and contributing to a more secure global landscape.
Mountain Combat Operations in the Context of Contemporary Battlefield Requirements
Authors: NISTORESCU Claudiu Valer
Published: July 2024

The integration of new technologies into military operations has a significant impact on the entire process, resulting in specific features and shaping the character of warfare. The modern battlefield is characterized by the accuracy and long range of new weapon systems, the extensive use of multi-spectral sensors, the continuous improvement of the sensor-to-shooter relationship, and the development of unmanned capabilities. In this context, there is a question as to whether military operations executed in mountainous environments are still relevant in contemporary battlefield equations. These operations are typically spatially limited, static, and attritional, and are subject to transformation from a doctrinal and operational perspective in a paradigm shift in the maneuversupport- fire-protection relationship. This study aims to identify and describe key factors associated with the adaptation of mountain warfare forces and the operations they conduct through an interpretive analysis of land operations.
Olha geográfico na percepção da cultura do Benzimento
Authors: PIMENTEL Julia Gessica Silva Oliveira , Silva Josue Costa
Published: July 2024

Ao estudar sobre uma cultura, com intuito de conhecer e compreender como se dá suas particularidades e perfil de resistência, se faz necessário um mergulho na percepção desta por parte de quem a vivencia, essa por sua vez é possível pela descrição do mundo e das experiências construídas em um determinado espaço. O Benzimento é um processo ritualístico que envolve o uso de orações, gestos, objetos e plantas medicinais, no intuito de trazer a pessoa adoecida um equilíbrio entre a mente, corpo físico e o espírito, pois de acordo com a cultura a doença é caracteriza pelo desequilíbrio desses três pontos. O ato de benzer se trata de uma intercessão pelo doente junto ao sagrado, sendo assim a benzedeira ou benzedor o agente intermediário entre essa conexão. Adentrar essa cultura foi possível através da fenomenologia, ela possibilita enquanto método submergir nas culturas e assim entender os espaços construídos com simbologias e representações particulares e únicas. O presente estudo representa parte de uma pesquisa de mestrado, que permitiu estudar sobre a cultura do benzimento, onde se buscou sobre as representações dessa cultura, suas particularidades, sacralização e simbologia que envolve os rituais do benzimento. A pesquisa possibilitou compreender os critérios de resistência, que envolve um passar de geração em geração e um “chamado especial” em alguns casos, que consiste na devoção de sua vida no cuidado e atenção ao próximo, envolvendo assim os aspectos de sacralização e fé que permeiam a cultura do benzimento.
Ritmo dos atributos climáticos durante ano-padrão muito chuvoso (2011) na cidade de Campina Grande, Paraíba, Brasil
Authors: Cavalcante Gabriel Paiva , Beserra Lucena Daisy , Oliveira Moura Marcelo
Published: July 2024

Este trabalho objetiva analisar o ritmo dos atributos climáticos do ar (temperatura máxima, temperatura média, temperatura mínima, pressão atmosférica, umidade relativa, velocidade do vento, direção do vento, precipitação e participação dos sistemas atmosféricos e das massas de ar) durante um ano-padrão classificado como Muito Chuvoso. Para o cumprimento de tal objetivo, é necessário seguir duas etapas: 1) eleger o ano-padrão Muito Chuvoso por meio da aplicação da técnica dos Quantis; 2) analisar os dados diários dos atributos climáticos. Após a execução dessas duas etapas, foi possível compreender os tipos de tempo que ocorrem na cidade de Campina Grande durante períodos chuvosos. Os dados climáticos foram obtidos nas seguintes fontes: o Instituto Nacional de Meteorologia – INMET (estações automática e convencional da cidade de Campina Grande) e a Agência Executiva de Gestão das Águas do Estado da Paraíba – AESA (postos pluviométricos). Após a aplicação da técnica dos Quantis, foi detectado que o ano de 2011 apresentou o maior registro de chuvas da série histórica entre os anos de 2005 e 2022, com um quantitativo de 1.494,4 mm (720,7 mm acima da média histórica, que é de 773,7). Com isso, sucedeu-se para a aplicação da técnica da análise rítmica. Foi observado que as chuvas ocorreram na cidade com mais frequência entre os meses de fevereiro e agosto, período de atuação de sistemas atmosféricos como a Zona de Convergência Intertropical – ZCIT e as Ondas de Leste – OL, principais produtores de chuva na cidade durante o ano.
Body Narratives from Posters and Popular Culture Article Sidebar
Authors: Aparna Dr.
Published: July 2024

The dichotomy of physically fit to fit in physical standards has emerged as a new question. Does the bikini industry promote the idea of appealing sizes or competitions that show beauty pageants and bodybuilders on popular media? The body has always been the contested site of people as whenever we meet someone after the first acquaintance, they ask why you are so thin. Or why do you look so fat? This narration is now changing into the new mold of being fit into that new dress. What if it doesn’t, the detrimental effect of not losing or not fitting into the set criteria has emerged in new disorders. The most recurring is the body dysmorphia which evolves due to the rule created by these competitions. Double XL movie produced in 2022, showcases a narrative about the body and for the body. Fashion movie produced in (2008), on models and beauty pageants that tries to cover the deformity of being the best yet ruins the foundation of being human. Bodybuilders and beauty pageants either create history and fame through steroids, unnecessary medication, and surgeries or just distort themselves physically as well as mentally. Physical attractiveness, prowess, and aesthetic appeal are just words that would wipe but talent, capability, and personality would stay forever. Thus, the body is nude yet crude, and therefore, the paper attempts to unwrap the problems staying in the heads of pageants and bodybuilders.
Cardiovascular and autonomic behavior of the use of combined therapy as a strategy to reduce abdominal fat: non-randomized clinical trial
Authors: Silva Laurinéia da , Almeida Nathália Soares de , Nogueira Amanda Meris , Eller Lizziane Kretli Winkelstroter , Abreu Marilda Aparecida Milanez Morgado de , Nakagaki Wilson Romero , Toledo Ana Clara Campagnolo Gonçalves
Published: July 2024

Introduction: Physiological and therapeutic changes promoted by combined therapy (CT) can act as a stressor for the body and generate changes in cardiovascular and autonomic behaviors. Objective: To analyze changes in body composition, cardiovascular variables, and heart rate variability (HRV) indices after applying CT in young women. Materials and Methods: Non-randomized clinical trial, 41 volunteers, using oral contraceptives, passive, and with a 4 cm supra-iliac skin fold. During 12 visits to the beauty center, initial and final assessments were carried out (anthropometric: body mass index, skin fold, percentage of body fat; cardiovascular: heart rate and blood pressure; and autonomic (HRV indices) and 10 CT sessions Results: After the 10 CT sessions, there were reductions in skin fold values ​​and percentage of body fat (p<0.05). However, there were no differences in cardiovascular variables or HRV when comparing the moments before and after ten sessions. CT sessions (p>0.05). Conclusion: The combined therapy proved effective in reducing localized fat and safe in terms of changes in HRV indices without causing changes in blood pressure.
The investigative learning and its daily applicability
Authors: Barrelo Junior Nelson , Quevedo Francisco da Veiga
Published: July 2024

This paper compares the effectiveness of collaborative teaching methods with traditional expository approaches in high school physics classes. Through bibliographical review, it discusses the definitions and differences between collaboration and cooperation to establish clear terminology. Initially, the paper examines the limitations of expository teaching methods and the benefits of collaborative teaching, drawing on Vygotsky’s concepts such as the Zone of Proximal Development (ZPD) and the idea of the most capable pair. It also looks at how these concepts are recommended for classroom use according to official Brazilian documents, like the National Common Core Curriculum (BNCC) and the Law of Guidelines and Bases of National Education (LDB 9394/96). Collaborative teaching through investigative methods significantly improves learning quality and helps students become more employable. Lastly, the paper compares investigative methodologies with approaches from other fields, such as group therapy and pair programming, to highlight their advantages and applicability.
Türk Akademisinde Arap Şiiri Konulu Bilimsel Makalelerin İçerik Analizi
Authors: Arslan Adnan
Published: July 2024

Herhangi bir alanda akademik çalışma yapmak istenildiğinde önce konu çerçevesinde bir lteratür taramasının lüzumu bilinen bir gerçektir. Türkiye’de Arap dili ve edebiyatı/belâgati alanında kaleme alınan ilk makaleden günümüze kadar binlerce akademik yayın birikimi hâsıl olmuştur. Bu çalışmada Akademik ver tabanlarından ve alana dair kaleme alınmış dizinlerden hareketle sahada teşekkül etmiş bu makalelerden Arap şiiri çerçevesinde kaleme alınmış olanların bibliyometrik ve içerik analizi amaçlanmıştır. Arap şiiri özelinde böyle bir çalışmanın ilk oluşu makalenin önem ve özgünlüğünü oluşturmaktadır. Son yıllarda aynı konuda birden fazla makalenin telif edildiğinin görülmesi ve alan içerisinde bazı noktalara yoğunlaşıp bazı konuların görece ihmal edildiğinin gözlemlenmesi bu makalenin hareket noktasıdır. İsam Makale Veri Tabanı ve Dergipark platformları konu çerçevesindeki veri sağlanmasında temel kaynak olmuştur. Anahtar kelimeler, başlıklar, makale öz/özetleri, Arap şiiri üzerine çalışmalar yapan akademisyenlerin yayın listeleri vb. araçlar üzerinden elde edilen künye bilgileriyle bir liste oluşturulmuştur. Elde edilen nicel veriler anlamlandırılmaya çalışılmıştır. Arap şiiri konulu çalışmalarda incelenen şairlerin sayısı, makale konusu, karşılaştırmalı çalışmalar, yıllara göre yayın adedi, konu özelinde yayın yapan akademisyenlerin yayın sayısı vb. parametreler esas alınarak istatistiki sonuçlar elde edilmeye çalışılmıştır. Sonuç olarak; incelemeye konu olan 624 makale içerisinde incelenen şairlerin en çok Abbasiler ve Modern döneme ait şairler olduğu tespit edilmiştir.
An Analytical Study on Household Income and Consumption Patterns in District Bagh, Azad Jammu & Kashmir
Authors: Waqar Muhammad Khan  , Ume Kalsoom  , Fouzia Sultana  , Noreen Akhtar
Published: July 2024

The research is an experimental exploration of the domestic income and expenditure in district Bagh AJ&K (Pakistan). The study utilized primary data of March 2020 gathered through a well-developed cum comprehensive questionnaire. It comprised a sample of 400 households selected through random sampling technique. The outcome was analyzed by applying “ordinary least square” (OLS) “regression model” and ANOVA test. Results of the study showed that relationship between income of household and domestic consumption is positive and significant. It means that the increase in the domestic income also increases their consumption. This result also contented the Keynesian theory on consumption. There is no significant impact occurred to take the gender of household and consumption. So, this study omits this variable from the model. There was a positive and substantial relationship existed between household age and domestic consumption. Households’ education and domestic consumption also had a constructive and meaningful relation. It means that educated people spend more as compare to less educated. There was a negative and noteworthy relationship existed between family structure and household consumption. Family size and household consumption had been also completely correlated. Nonetheless, the research determined that both economic factors and demographic features affect household consumption pattern in district Bahg AJ&K. Policy makers should formulate policies designed to increase the income level of employees for enhancing their buying power, decreasing their deficit and to increase their saving which would definitely ensure a sophisticated living standard of the study area.
lnteligencia artificial aplicada al riesgo de las viviendas: Una revisión de literatura
Authors: Balcero Sebastián , Velásquez Gómez Jhon Esteban , Rodríguez Olaya Julián , Aguiar Jaramillo Daniel Esteban , Montoya Suárez Lina María , Gil Vera Víctor Daniel
Published: July 2024

En Colombia existen viviendas que fueron construidas de manera empírica sin estudios especializados de suelos ni valoraciones previas de los materiales de construcción, lo que las ha llevado al colapso por la aparición de fenómenos naturales. En la actualidad, la lnteligencia Artificial (IA) se ha convertido en una gran herramienta para la realización de tareas complejas, como lo puede ser determinar el grado de vulnerabilidad o el riesgo de colapso de una obra civil. El objetivo de este trabajo es presentar una Revisión Sistemática de la Literatura (RSL) sobre cómo se ha aplicado la Inteligencia Artificial (lA) en la identificación de riesgo de colapso de viviendas. Se concluye que, si bien la IA no puede prevenir directamente los derrumbes de viviendas, puede ayudar a identificar y mitigar los factores que contribuyen a tales eventos; principalmente, a través del uso de sensores para monitorear continuamente la salud estructural en tiempo real y detectar signos de deterioro, estrés u otros problemas que podrían provocar un colapso.
CVD Case Series: Screening and Risk Reduction
Authors: Woldemichael Ruth , Graves Cornelia , Hameed Afshan
Published: July 2024

Undetected cardiovascular disease is one of the leading causes of complications during pregnancy in the United States. Maternal mortality reviews indicate that lack of suspicion and delays in diagnosis are the primary drivers of CVD-related mortality. Purpose of this study is to examine the effect of implementing the CVD (Cardiovascular Disease) Risk Assessment tool developed by the California Maternal Quality Care Collaborative (CMQCC) team in 2018. Eligibility of patients in the case series was determined through CVD risk screen score of 4 or higher using a standardized stool adopted from the CMQCC. The patient was scored at the point of hospital entry. Factors used in scoring included symptoms, vitals and risk factors. Patients who scored positive were sent for further work up. This included in-depth analysis of other significant clinical factors influencing patient presentation and subsequent management. The CV patient cases presented in this case series illustrate the benefits of early identification and implementation of standardized CVD risk assessment. There are significant benefits in early use of the CV screening tool contributing to mortality risk reduction including continued close antenatal surveillance, postpartum follow-up, and continued collaborative multidisciplinary care. Patients with risk factors underwent continued surveillance and received appropriate specialized follow-up that allowed for improved maternal outcomes. Proper implementation of CVD risk assessment tool for patients who are at-risk of development of CVD in pregnancy can effectively reduce adverse maternal outcomes related to cardiac disease.
Role of Non-Timber Forest Products (NTFPs) in rural livelihoods: A study of Dabhaura Forest Range in Rewa district of Madhya Pradesh (India)
Authors: Bhatnagar Pratibha , Barman Rajesh
Published: July 2024

This study focuses on the socio-economic importance of Non-Timber Forest Products (NTFPs) in the Rewa district of Madhya Pradesh. The research explores the demographic profile, NTFP collection practices and economic contributions of NTFPs to income of rural households in four selected villages. The findings reveal that NTFPs, particularly Tendu leaves, Mahua flowers, Mahua fruit, and Gudmar leaves, significantly contribute to the livelihoods of local communities. The study emphasizes the critical role of NTFPs, especially among rural populations and underscores the need for sustainable practices and market interventions to enhance the well-being of these marginalized communities.
Towards Efficient Hyperspectral Object Detection and Classification using Thermal Optimization Algorithm with Deep Learning
Authors: Noor Noor ,   Baghdad University, College of Science, Baghdad, Iraq
Published: July 2024

Object detection in remote sensing images (RSI) is a main procedure where the purpose is to automatically recognize and categorize certain objects or features from large-scale, remotely developed images like aerial imagery or satellite. This task role a vital play in extracting appreciated data from massive geographical regions, contributing to various applications under several domains namely environmental monitoring, urban planning, agriculture, and disaster management. Recent developments in deep learning (DL) technologies have significantly enhanced the accuracy and efficacy of object detection systems for RS, enabling more precise and automated analysis of various landscapes and facilitating informed decision-making. DL approaches namely convolutional neural networks (CNNs) are exposed to remarkable abilities in learning intricate patterns and features from difficult spatial data, resulting in enhanced accuracy and effectiveness. In this article, we present a Towards Efficient Hyperspectral Object Detection and Classification using Thermal Optimization Algorithm with Deep Learning (HODC-TOADL) system. The objective of HODC-TOADL algorithm is to identify and categorize distinct types of objects that exist in the RSI. In the HODC-TOADL method, an improved Dense Net model is applied to learn the distinct features of the input RSI. Besides, the TOA has been deployed to boost the hyper parameter choice of the Dense Net method. Furthermore, the classification of objects can be carried out by employing of adaptive neurofuzzy inference system (ANFIS). The experimental evaluation of the HODC-TOADL algorithm can be studied on benchmark databases. The experimental values stated that the HODC-TOADL algorithm reaches effective classification performance compared to recent DL models.
Analisis Perkembangan Berpikir Kritis Siswa dalam Pembelajaran Matematika Perspektif Studi Longitudinal
Authors: Suwarma Dina Mayadiana , Hersiyati Palayukan  , Nasruddin  , Sitti Rahmayani  , Syarifuddin
Published: July 2024

This research explores the development of students' critical thinking in mathematics learning through a longitudinal study approach. With a focus on problem solving, creative thinking, and conceptual understanding, this study aims to understand how students develop critical thinking skills over time. A longitudinal research method was used with 100 students from two secondary schools in Medan city as participants. Results showed significant improvements in students' critical thinking scores from the beginning to the end of the semester, with teacher training interventions and differences between schools making significant contributions. The implication of this study is the importance of innovative learning approaches and support for teachers in improving students' critical thinking skills in the context of mathematics learning
Determining Efficacy of Intracanal Cryotherapy on Post Endodontic Pain in Irreversible Pulpitis
Authors: Bashir Anam Fayyaz , Jatala Ussamah Waheed , Ahmad Moeen ud din , Khan Muhammad Talha , Khan Saima Razzaq , Butt Aisha Arshad
Published: July 2024

Endodontic cryotherapy is a procedure that reduces pain and inflammation by applying cold to tissues, aiming to decrease post-endodontic pain. Objectives: To compare the effectiveness of cryo-treated endodontic irrigant in reducing post-endodontic pain in mandibular molars with irreversible pulpitis. Methods: This comparative analytical study was conducted from December 2023 to February 2024 in the Department of Operative Dentistry at Lahore Medical and Dental College. It included patients of both genders, aged 18 to 60, with symptomatic irreversible pulpitis in mandibular molars and pre-endodontic pain of VAS 7-10 for 10 days or less. Patients were divided into two groups: Group A (normal saline) and Group B (cryotherapy). Patients were instructed on using the Visual Analogue Scale (VAS) to assess pain. Group B received final irrigation with 20 ml normal saline at 2.5°C for 5 minutes, while Group A received 20 ml normal saline at room temperature. Pain scores were recorded preoperatively and at 24 and 48 hours’ post-treatment via telephone interviews. Data were analyzed using SPSS version 25 and a repeated measures ANOVA test assessed VAS scores across time points. A p-value <0.05 was considered significant. Results: 45 (46%) were male and 53 (54%) were female patients, with mean age of patients being 35.71 ± 10.71years. At 24 hours postoperatively, the mean VAS score was 1.51 ± 1.2 for the normal saline group and 0.98 ± 0.9 for the cryo-treated saline group. By 48 hours postoperatively, the mean VAS score further decreased to 0.27 ± 0.5 for the normal saline group and 0.12 ± 0.4 for the cryo-treated saline group. The mean differences in VAS scores at 24 hours showed significant difference in mean pain score (P-value<0.05) but at 48 hours between the two groups showed no significant difference (p = 0.104). Conclusions: Both saline groups significantly decreased pain, the type of saline, normal or cryo-treated, did not significantly impact overall pain scores differently between the groups.
The Role of Cerebrospinal Fluid High-Sensitivity C–Reactive Protein (CSF hsCRP) in Distinguishing Bacterial Meningitis from Aseptic Meningitis
Authors: Ahsan Umaira , Arshad Faiqa , Khan Rao Shahzad Abdul Tawwab , Naz Muneeba , Pervaiz Saima , Rao Omer Shahzad Khan , Rehman Attiq ur
Published: July 2024

One of the most prevalent serious diseases in newborns and infants is meningitis. Aseptic meningitis is generally less severe than bacterial meningitis and often has a better prognosis. CRP level is the most useful criterion for diagnosing feverish children with significant infections. Objective: The present study aimed to determine the level of CRP in CSF of bacterial meningitis, and aseptic meningitis for early prediction of meningitis and remove the lapse in its treatment. Methods: This cross-sectional study was conducted at the Immunology Department of The Children’s Hospital & the Institute of Child Health from Jan 2022 to Jan 2023. The present study enrolled patients who had meningitis symptoms (fever, headache, vomiting, and neck stiffness), aged between >2 years to 12 years, both male and female gender. The CRP levels of all patients were measured using the agglutination method. Data were analyzed using IBM-SPSS version 26.0. Results: Of the total 45 patients, 20 (44.4%) were males and 25 (55.6%) were females. The mean age of patients was 5.98+2.792 years. From total, 29 (64.4%) had bacterial meningitis while 16 (35.6%) had aseptic meningitis. The 09 (31.03%) bacterial meningitis patients had positive CRP (>3.0mg/L). The present study showed a statistically significant association between CSF-CRP results with bacterial and aseptic meningitis (p=0.003). Conclusions: While awaiting the results of other confirmatory tests, CSF-CRP can be utilized as an early diagnostic tool for the identification of bacterial and aseptic meningitis. Additionally, it could aid in the early diagnosis of aseptic vs bacterial meningitis.
Safety of Long Acting Reversible Contraception (LARC) during 3 Months of Follow up At Civil Hospital, Karachi
Authors: Tariq Sidra , Farhan Anum , Tasneem Maria , Meer Sumaira , Khan Daniya , Sabir Sadaf
Published: July 2024

Contraception counseling is an essential component of family planning services. It provides the foundation for delivering correct information on contraceptive methods and eliminating myths regarding risks and negative effects. Objectives: To determine the Safety of Long-Acting Reversible Contraception (LARC) for postpartum contraception during 3 months of follow-up. Methods: A cross sectional descriptive study comprised on total of 108 women aged 25-35 years who accepted LARC in the postpartum period at Department of Obstetrics and Gynaecology, Civil Hospital, Karachi from 22nd February 2021 to 21st August 2021, were included. Females with uterine abnormalities and severe anemia were excluded. The demographic information (name, age, registration number) was taken. The women were counseled regarding postpartum contraception LARC such as IUD or Jedelle (implant) during the antenatal period and LARC was placed within 30 minutes of placental delivery. Those women who selected LARC were called for follow-up for 3 months in OPD and at follow-up visits, patients were assessed for their safety of this method. Results: The age range in this study was from 25 to 35 years with a mean age of 28.81 ± 3.27 years. The majority of the patients 80 (74.07%) were between 25 to 30 years of age. The mean parity was 3.10 ± 0.72. In this study, the safety of Long Acting Reversible Contraception (LARC) for postpartum contraception during 3 months of follow-up was found in 91 (84.26%) women. Conclusions: This study concluded that long acting reversible contraceptives in the immediate postpartum period are very safe.
Major considerations of the nutrients, probiotics and gut microbiota in the treatment of psoriasis and atopic dermatitis: a concise systematic review
Authors: Rocha Michelle Silva , Aquino Lorenna Lemos de , Lopes Vinícius Bezerra , Soares Raimundo Nonato de Araújo , Braga Mayta Queiroz Monteiro , Borges Thais Fernandes , Freitas7 Jorge Luiz de , Barbosa Sonaldo Marcos Vieira , Carneiro Lucianna Rodrigues , Loro Pâmela Crestani
Published: July 2024

Introduction: Skin conditions contributed 1.79% to the global burden of 306 diseases and injuries in recent years. Individual skin diseases varied in size, from 0.38% of the total burden for atopic dermatitis (AD), 0.29% for acne vulgaris, and 0.19% for psoriasis. The microbiome of normal human skin showed high diversity and high interpersonal variation. Imbalance of the intestinal microbiota can promote the onset and progression of human diseases. Objective: It was analyzed, through a systematic review, the main considerations of the nutrients, probiotics, and gut microbiota in the treatment of psoriasis and atopic dermatitis. Methods: The PRISMA Platform systematic review rules were followed. The search was carried out from January to April 2024 in the Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 120 articles were found, and 29 articles were evaluated in full, and 20 were included and developed in the present systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 23 studies with a high risk of bias and 25 studies that did not meet GRADE and AMSTAR-2. Most studies showed homogeneity in their results, with X2=79.5%>50%. It was concluded that aesthetically healthy skin includes manipulation of intestinal function. Treatments that augment or repair a leaky gut barrier may become important as adjunctive therapy in the management of inflammatory skin conditions and may help increase the effectiveness of standard dermatotherapy. All of this would be aimed at modifying the secretory, metabolic, and hormonal activity of the intestinal epithelium to impact skin inflammation.
Exploring the multifaceted Antioxidant capacities and molecular composition revealed through LC/MS analysis of Phyllanthus niruri, Solanum xanthocarpum, and Tecomella undulata plant extracts
Authors: Munjani Dipalee , Godhani Dinesh , Mehta Jignasu
Published: July 2024

A diverse range of phytochemicals, including Phenols (TU: 70.3 µg/g in RS), Flavanoids (PN: 185.1 µg/g in AC), Tannins (TU: 18.0 µg/g in EA), Alkaloids (PN: 280.0 µg/g in AC), Ascorbic acid (TU: 300.0 µg/g in CH) and Terpenoids (TU: 4.0 µg/g in RS), were detected and estimated in the plant extracts. LC/MS analysis spotted various phytochemical compounds, including phenolic (Coniferyl aldehyde), flavonoid (Myricetin), alkaloids (Anagyrine, Sophoramine), vitamins (Riboflavin, Ascorbic acid) monoterpene alcohols (Lavandulol, Geraniol, Linalool, Citronellol Nerol), diterpenoid (Ferruginol), and sterols (Sitosterol, Campesterol). The antioxidant activity of the extracts using multiple assays. The plant extracts displayed remarkable antioxidant capacity for DPPH free radical, Superoxide radical scavenging antioxidant activity, phosphomolybdate antioxidant activity. These findings highlight the diverse phytochemical composition of plant extracts and their potential utility in various biological and pharmacological applications.
Gestão editorial com Open Journal System (OJS): benefícios da Revista Angolana de Ciências
Authors: Machado Sousa João Baptista
Published: July 2024

X