bluuebunny/crossref_metadata_2025 huggingface dataset:
To Rebuild or to Refurbish? An Analysis of the Financial Convenience of Interventions on Urban Consolidated Contexts
Authors: Locurcio M. , Tajani F. , Morano P. , Liddo F. Di , Anelli D.
Published: January 2022

In the current historical moment of post-crisis recovery, the real estate sector has a dual role: i) through the construction industry and its impacts on related economic sectors, it is called upon to be an active part of the economic recovery; ii) the enhancement of existing property assets is of primary importance in the containment of greenhouse gases and the achievement of the objectives set by the United Nations [1]. In this context, the various players involved in the real estate market have outlined the importance of being supported by assessment methodologies. That allows to point out not only the opportunities of the investment, but also the risks that may invalidate the initial forecasts, nullifying the success of the initiative. To this end, this research develops a multi-criteria Key Performance Indicator aimed at analyzing the feasibility of real estate initiatives that allows to provide a synthetic scoring on the financial sustainability of each investment and to compare different types of initiatives (e.g. new construction, demolition and reconstruction, renovation, etc.).
A Novel low power 2-D to 3-D Array Priority Encoder using Split-Logic Technique for Data Path Applications
Authors: Sam D. S. Shylu , Paul P. Sam , Elizah Jennifer , , Nithyasri Nithyasri , Snehitha Snehitha , Singh Akansha , Vijendra Vijendra
Published: January 2022

In this work, an ascendable low power 64-bit priority encoder is designed using a two-directional array to three-directional array conversion, and Split-logic technique and 6-bit is obtained as the output. By using this method, the high performance priority encoder can be achieved. In the conventional priority encoder, a single bit is set as an input, but for a priority encoder with 3-Darray, every input are specified in the matrix form. The I-bit input file is split hooked on M × N bits, similar to 2-D Matrix. In priority encoder with 3-Darray, three directional output comes out, unlike traditional priority encoder, where the output is received from one direction. The development can be achieved by implementing the two-directional array to three-directional array technique. Simulation results show that the proposed 2-D and 3-D priority encoder consumes 0.087039mW and 0.184014mW which is less when compared with the conventional priority encoder. The priority encoders are simulated and synthesized using VHDL in Xilinx Vivado version 2019.2 and the Oasys synthesis tool.
Exact Command Tracking Control Computations without Integration
Authors: Tsay Tain-Sou
Published: January 2022

A digital controller for exact command tracking control without integration is derived from a periodic series. The ratios of adjacent values will be converged to unities after the output has tracked the reference input command. Integration in control loop usually introduces phase lag to slow command response and degrade performance.
Action: A New Metric for Evaluating the Energy Efficiency on High Performance Computing Platforms (ranked on Green500 List)
Authors: Karanikolaou E. M. , Bekakos M. P.
Published: January 2022

The need for new and more reliable metrics is always in demand. In this paper, a new metric is proposed for the evaluation of high performance computing platforms in conjunction with their energy consumption. The aim of the new metric is to reliably compare different HPC systems concerning their energy efficiency. The metric provides a mean to rank supercomputers of similar capabilities, avoiding the misleading results of metrics like performance-per-watt, currently used for ranking systems, as in the Green500 list, where systems with totally different sizes and capabilities are ranked consecutively. An example of this misuse for two adjacent systems in the Green500 list, is discussed. A comparative study for the energy efficiency of three high performance computing platforms, with different architectures, using the proposed metric is presented.
A Modified XG Boost Classifier Model for Detection of Seizures and Non-Seizures
Authors: Raveendra Kumar T. H. , Narayanappa C. K. , Raghavendra S. , Poornima G. R.
Published: January 2022

Diagnosis of Epilepsy is immensely important but challenging process, especially while using traditional manual seizure detection methods with the help of neurologists or brain experts’ guidance which are time consuming. Thus, an automated classification method is require to quickly detect seizures and non-seizures. Therefore, a machine learning algorithm based on a modified XGboost classifier model is employed to detect seizures quickly and improve classification accuracy. A focal loss function is employed with traditional XGboost classifier model to minimize mismatch of training and testing samples and enhance efficiency of the classification model. Here, CHB-MIT SCALP Electroencephalography (EEG) dataset is utilized to test the proposed classification model. Here, data gathered for all 24 patients from CHB-MIT Database is used to analyze the performance of proposed classification model. Here, 2-class-seizure experimental results of proposed classification model are compared against several state-of-art-seizure classification models. Here, cross validation experiments determine nature of 2-class-seizure as the prediction is seizure or non-seizure. The metrics results for average sensitivity and average specificity are nearly 100%. The proposed model achieves improvement in terms of average sensitivity against the best traditional method as 0.05% and for average specificity as 1%. The proposed modified XGBoost classifier model outperforms all the state-of-art-seizure detection techniques in terms of average sensitivity, average specificity.
Problems and Compliance on Online Education among Nursing Students
Authors: Jessy Thomas
Published: January 2022

A descriptive study was conducted to assess the problems and compliance on online education amongnursing students, KIMS nursing college Thiruvananthapuram. The objectives of the study were to findout the problems of online education, to assess the compliance of online education, to find out theassociation between problems and compliance of online education and selected sociopersonal variables.The sample size consists of 110 nursing students. The study used a purposive sampling techniquethrough a structured questionnaire consisting of 3 sections; section A consist of Sociopersonal variablesuch as age, year of study, gender, monthly income, area of residence, and gadgets used for onlinelearning; section B is a structured questionnaire of 10 multiple choice questions on problems of onlineeducation; Section C consists of 15 “Yes /No” question on compliance of online education. Data wascollected and analysed using descriptive and inferential statistics. The selected socio-personal variablesin the study include age, gender, year of study, income, area of residence, gadgets used for learning.The result show that 58.181% participants faced network, electricity, recharge issues, 56.36% spend 5-7hours for an average online section, 57.27% felt that online education was good, 70% partially completedthe class syllabus, 64.545% reported too much content, 49.090% preferred whatsApp,.30.90% felt asense of isolation, 53.62% had partially affordable economic burden,76.3% experienced headache, eyestrain and backache,52.73% doesn’t get enough time to engage in physical activity and about 40.90 %had average compliance, 33.63% good and 25.45% had poor compliance.The study showed that there is a significant association between compliance on online education andage (P<0.05). There is no significant association between compliance on online education and gender,year of study, income, area of residence and gadget used.
Identification of Physical Problems of Patients with Acute Stroke
Authors: Nihitha Jose  , Mini. G
Published: January 2022

Background: Stroke patients experience a variety of physical problems which affect their activitiesof daily life. As there is need for identifying the physical problems of patients with acute stroke in theinitial stage, the present study was undertaken to identify the physical problems of patients with acutestroke. Objectives: the objectives of the study were to identify the physical problems of patients withacute stroke. Methods: This descriptive study was conducted at neurology department of a tertiarycare hospital in Kerala. 60 patients with acute stroke was selected by consecutive sampling technique.Physical problems of stroke patients were identified by standardised tools; National Institute of HealthStroke Scale (NIHSS) and Barthel index. Appropriate descriptive and inferential statistical methods wereused to analyze the data. Results: The major physical problems identified were immobility (81.7%),lower extremity weakness (75%), upper extremity weakness (71.6%), loss of bladder control (66.7%),loss of bowel control (65%), feeding problem (63.3%) and communication problems like dysarthria(55%) and aphasia (53.3%). Conclusion: The study stresses the importance of identification of variousexisting and emerging physical problems encountered by acute stroke patients and the preparation of anursing care protocol, which can be utilized in future, for managing the major physical problems.
Eficiencia del proceso de cloración en la eliminación de coliformes termotolerantes en una planta de tratamiento de agua potable
Authors:   Universidad Nacional Autonoma de Chota, Gonzales Vasquez Wilmer , Núñez Figueroa Mariela
Published: January 2022

The efficient removal of thermotolerant coliforms in drinking water is essential for human health. For this reason, the objective of the work carried out was to determine the efficiency of the chlorination process in the elimination of thermotolerant coliforms from the “Santa Rosa” Drinking Water Treatment Plant (PTAP) - Chota. 10 samples of water distributed in the rainy and dry season were carried out for both raw water and treated water. Data analysis was performed using simple samples. Good bacteriological quality was defined: water with adequate free chlorine, absence of total coliforms. To take water samples, the Protocol established by the General Directorate of Environmental Health (DIGESA) of the Ministry of Health was taken into account. The results determined the presence of thermotolerant coliforms in raw water, with variations from 149 NMP / 100mL to 168 NMP / 100 mL respectively; however, the chlorination process managed to eliminate thermotolerant coliforms with an efficiency of 100%. The treated water met the Maximum Permissible Limits (LMP) for water for human consumption.
The Effect of Exposure to Positive Indonesian National Army News on Covid-19 in Online Media on the Attitudes of the People of Bajawa City
Authors: Wou Silvinus , Andung Petrus Ana , Meilawati Fitri Titi
Published: January 2022

One of the news that has caught the attention of the Indonesian people since 2019 until now is the news about Covid-19. The purpose of this study was to analyze the effect of exposure to 41 TNI reports that were positive for Covid-19 in online media on people's attitudes in Bajawa City. The approach in this research is quantitative with a survey method. The sampling technique used is the purposive sampling technique and the sample obtained is 100 people. The theory used in this research is the Agenda setting theory. The study results found that there was an influence between news exposure of 41 soldiers with positive Covid-19 in online media towards people's attitudes in Bajawa City. This is evidenced by the presence of some respondents who are more afraid of news of death due to Covid-19 and do not understand how to prevent Covid-19.
Strategy of the Majalengka Regency Tourism and Culture Office in Promoting Paragliding Tourism Destinations
Authors: Yasmin Prahastuti , Haq Mochammad Fauzul , Akil Rafiuddin
Published: January 2022

This research is backgrounded by the huge potential of tourism sector in Majalengka but in fact it cannot be maximized by the government. One of the most popular tourist destinations this time is Paragliding. Although the promotion has been carried out by the local government through tourism and cultural office of majalengka, even it has been covered by national TV stations, but still the visit to paragliding is only dominated by local tourists. This is a problem because paragliding tourist destination is like march in place even though the promotions have been made. This study explored using marketing communication theory that focuses on 5 dimensions of the promotion mix, namely: advertising, direct marketing, personal selling, sales promotion, and public relations. In addition, the concept of promotion strategy that divides into two types, namely: push strategy and pull strategy is used to determine the promotion strategy applied by the tourism and culture office of Majalengka. The concept of tourist destinations that focuses on 5 variables: attraction, accessibility, amenities, ancillary services, and institutions are used to explore paragliding tourism destination itself. The research was carried out with a qualitative methodology of constructivism paradigm. The results showed that the tourism and culture department of Majalengka did not run maximally the promotion mix as it should be, advertising was not carried out continuously and periodically, public relations was not conducted, direct marketing was still done in traditional ways such as the use of pamphets and CDs.
Public Relations Strategy in Improving Cinema Company Reputation (Case Study Cinema21)
Authors: Safitri Karina Khairunnisa , Sonya Putri , Wattimena Nico
Published: January 2022

Human beings needs to fulfill their life, entertainment is one of them. In this era of digitalization there are various form of enrtainment, one of them is cinema. CINEMA 21's is the largest and vast growing group of cinemas in Indonesia with many branches nationwide. CINEMA 21 public relations always try to improve their reputation by providing best facilities to its customers. The purpose of this research, is to analyze CINEMA 21's public relations activities to improve their reputation. The research method used is qualitative descriptive with primary data collection conducted through in-depth interviews with internal and external corporate sources, while secondarydata through company data (Company Profile), books, Internet (Articles) and Websites. The results of this research found that CINEMA 21's public relations activities managed to maintain the company's reputation.
Foraminiferal zonation of a boring in Quaternary deposits of the northern North Sea
Authors: W. Feyling-Hanssen R.
Published: January 2022

The foraminiferal content of samples from a 122 m deep borehole in the Statfjord Field of the northern North Sea permitted a biostratigraphical subdivision of the sequence into 11 units. The paleoecology of these units is discussed. Most of them reflect High-Arctic ice age conditions, whereas two of them are of interstadial character. Distinctly ameliorated assemblages occur 20 m below sea floor. They correlate with late Statfjord Interglacial assemblages from a previously described boring and probably originate from the end of the Eemian. An attempt has been made to correlate the units of the present boring with published deep sea oxygen isotope stages.
Late Turonian-early Coniacian belemnites from western and central Europe
Authors: Christensen Walter Kegel
Published: January 2022

A little known fauna of late Turonian--early Coniacian belemnites from the Central European palaeobiogeographic Subprovince is revised and the following species are recognised: Actinocamax strehlensis (Fritsch & Schlonbach), A. bohemicus Stolley, A. paderbornensis Schliiter, and A. esseniensis n. sp. The taxonomic value of various characters within Late Cretaceous belemnites belonging to the family Belemnitellidae Pavlov is discussed, and it is concluded that the shape of the guard is a more significant taxonomic character than the presence of granules. The species from the subprovince are compared to coeval species from the Central Russian Subprovince and the North American Province. The palaeobiogeography and evolutionary trends of early Late Cretaceous belemnites are discussed.
The significance of a Middle Devonian Kl Ar age of an intrusive rock in the southern part of the North Greenland Fold Belt
Authors: A. Schack Pedersen Stig , Martin Holm Paul
Published: January 2022

A Kl Ar age of 380 ± 5 Ma has been obtained from an intrusive body in the· southern part of the North Greenland Fold Belt in Peary Land. This age dates the first major deformation event in the North Greenland Fold Belt, and it is inferred that a correlation exists between the North Greenland Fold Belt and the Northern Ellesmerian Fold Complex of the Arctic Canadian archipelago. The dating furthermore casts serious doubt on the proposed genetic link between the intrusive rocks of the southern part of the North Greenland Fold Belt and the Late Cretaceous Kap Washington volcanics and the N-S trending dyke swarms W of Peary Land.
Radiocarbon dating of a mammoth tusk fragment from Brorfelde, Denmark
Authors: Selsing Lotte
Published: January 2022

Fragments of three elephantine tusks have been found in ice transgressed fluvioglacial deposits at Bror­felde, northwestern Sjrelland, Denmark. Four '"C datings have been carried out on one of the fragments (Tusks 2) of a mammoth tusk (Mammuthus primigenius Blumenbach). They constitute the first radiocar­bon datings of Danish mammoth material. The age is given as the mean value of two collagen dates, 44 300􀁅];:ro years B.P. Techniques of the applied dating procedures are given to elucidate contamination problems and to compare with 1'C datings of mammoth tusks from other localities in northwestern Europe. The date of the Brorfelde Tusk 2 should be regarded as a maximum age of the Brorfelde deposits. The date 44 300 􀁍:􀁏gg years B.P. of this tusk fragment corresponds relatively well with the earliest Middle Weichselian interstadial recorded in other areas.
Effect of lubricants on the rotational transmission between solid-state gears
Authors: Lin Huang-Hsiang , Heinze Jonathan , Croy Alexander , Gutiérrez Rafael , Cuniberti Gianaurelio
Published: January 2022

Lubricants are widely used in macroscopic mechanical systems to reduce friction and wear. However, on the microscopic scale, it is not clear to what extent lubricants are beneficial. Therefore, in this study, we consider two diamond solid-state gears at the nanoscale immersed in different lubricant molecules and perform classical MD simulations to investigate the rotational transmission of motion. We find that lubricants can help to synchronize the rotational transmission between gears regardless of the molecular species and the center-of-mass distance. Moreover, the influence of the angular velocity of the driving gear is investigated and shown to be related to the bond formation process between gears.
Terpenoids from Glechoma hederacea var. longituba and Their Biological Activities
Authors: Kim Dong Hyun , Khan Zahra , Kim Sun Yeou , Choi Sang Un , Kim Chung Sub , Lee Kang Ro
Published: January 2022

Glechoma hederacea var. longituba (common name: ground-ivy) has been used for the treatment of asthma, bronchitis, cholelithiasis, colds, and inflammation. In the present study, three new sesquiterpene glycosides (1–3), two new diterpene glycosides (4–5), and four known compounds (6–9) were isolated from its MeOH extract. Structure elucidation was performed for the five new compounds (1–5) using 1D and 2D NMR, HRESIMS, ECD calculation, and chemical methods. All the isolates (1–9) were assessed for their anti-neuroinflammatory activity on nitric oxide (NO) production in lipopolysaccharide (LPS)-activated BV-2 cells, nerve growth factor (NGF) secretion stimulation activity in C6 glioma cells, and cytotoxic activity against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT15). Compounds 2 and 5–7 exhibited inhibitory effects on NO production with IC50 values of 52.21, 47.90, 61.61, and 25.35 μM, respectively. Compound 5 also exhibited a significant stimulating effect on NGF secretion (122.77 ± 8.10%). Compound 9 showed potent cytotoxic activity against SK-OV-3 (IC50 3.76 μM) and SK-MEL-2 (IC50 1.48 μM) cell lines, while 7 displayed a strong cytotoxic activity against SK-MEL-2 (IC50 9.81 μM) cell line
Analysis of the Effect of Service Quality on Corporate Image and Service Usage Decisions at PT. Biro Klasifikasi Indonesia (Persero)
Authors: Kholick Abdul , Kaihatu Thomas Stefanus
Published: January 2022

This study aims to determine the effect of service quality (X1) on corporate image (X2) and service usage decision (Y) of PT. Biro Klasifikasi Indonesia (Persero). The research approach taken is quantitative. The sampling technique used was non probability sampling with purposive sampling method. The number of samples in this study were 90 respondents with the criteria of consumers who have registered ships at PT. Biro Klasifikasi Indonesia and also has vessels registered with foreign classification agencies. The data collection method in this study used a questionnaire measured using a Likert scale and the data collected were analyzed Structural Equation Modelling with Partial Least Square. The program used is SmartPLS 3.0. Based on the results of the analysis that has been done, it is known that service quality has a positive and significant effect on the corporate image of PT. BKI, service quality has a positive and significant effect on the decision to use PT. BKI and corporate image have a positive and significant effect on the decision to use BKI.
The Effect of Job Stress and Reward System on Organizational Commitment and Employee Performance
Authors: Oya Adhisty Merrial
Published: January 2022

The purpose of this study was to investigate the relationship between job stress and reward systems on organizational commitment and employee performance. The subjects in this study were employees in manager level, namely IPOMS (Indonesian Production and Operation Management Society) with 119 respondents. The data collection method is done by distributing questionnaires using an interval scale of 1 to 7 and using data analysis methods Structural Equation Modelling (SEM) – Partial Least Square (PLS). The result showed that there is no significant relationship between work stress and organizational commitment, there is a significant relationship and positive between reward system and organizational commitment, there is no significant relationship between work stress and employee performance, there is no significant relationship between reward system and organizational commitment, there is a significant relationship and positive between organizational commitment and employee performance.
Risk factors for postanesthetic emergence delirium in adults: A systematic review and meta-analysis
Authors:   Affiliated Hospital of Chengdu University, He Miao , Zhu Zhaoqiong , Jiang Min , Liu Xingxing , Wu Rui , Zhou Junjie
Published: January 2022

Review question / Objective: Patientor population: patients with emergence delirium; Exposure: anaesthesia and surgery; Control: patients with no emergence delirium; Outcome: risk factors; Study design: meta-analysis. Eligibility criteria: To ensure the quality of this meta-analysis, inclusion criteria was decided before we carried out the search. These criteria were: (a) Original researches that carried out in observational studies. (b)Adult patients who were extubated and recovered at PACU, operation room, or intensive care unit (ICU) after surgeries and anesthesia (including general and neuraxial anesthesia, peripheral nerve blocks and sedation). (c) Risk factors for delirium must be assessed with odds ratio (OR) with 95% confidence interval (CI). Researches must present the results of multivariate regression to be considered eligible for inclusion, since multivariate analysis results shall be used to identify variables eligible for meta-analysis. (d) Full-text available literatures.
First national point prevalence survey of healthcare-associated in-fections and antimicrobial use in acute care hospitals in the Republic of Moldova
Authors: BUSUIOC Ecaterina , CATERINCIUC Natalia
Published: January 2022

Introduction. HAIs present a major public health problem with an impact on morbidity, mortality and quality of life. The objective of the study was to highlight the problem of HAIs and AM use, identification of risk factors and raising awareness of the phenomenon.

Material and methods. The methodology of the PPS was patient-based, developed based on ECDC Protocol 5.3/2016. The study was accomplished in 2018. The sample of the PPS included 67 hospitals, 546 wards and 10594 patients.

Results. The prevalence of HAIs was 1,6%, with predominance of pneumonia (25%), SSI (16.1%), LRI (14.9%), UTI (11.3%) and varies depending on the wards profile, clinical diagnosis, length of hospital stay and risk factors (medical device, surgery). HAIs were caused by Klebsiella spp. in 26%, Enterococcus spp. – 18% and coagulase-negative Staphylococci – 14%, P. aeruginosa – 12%. Klebsiella spp. presented resistance to 3rd generation cephalosporins in 84,6% and to carbapenems – 46.2%. The prevalence of AM use was 42.7%, for the group of 3rd generation cephalosporins – 34.5%. More frequently antibiotics were administered for treatment (73.8%), and for surgical prophylaxis >1 day in 93.5%.

Conclusions. Data on HAIs and AM consumption in hospitals, first obtained by implementing active surveillance based on the ECDC tool, are standardized and comparable at national and international level and allow assessing the situation in hospitals, obtaining evidence for infection prevention and control and AM stewardship programmes at local level, as well as reasoning the national policies.
Gold nanoparticles from magnetite for the detection of amyloid proteins in neurodegenerative diseases
Authors: ORTIZ Alejandro , HERRERA Zeyris , MOSCOSO Johanna
Published: January 2022

Introduction. Currently, neurodegenerative diseases (ND) are the fourth leading cause of death worldwide that pose a great challenge in the development of tools for early diagnosis. Thus, advances in science seek sensitive and selective detection systems and this manuscript will highlight the importance of nanotechnology.

Material and methods. A literature review was conducted on the representative findings of NPs technologies in neurodegenerative diseases. Articles written in both English and Spanish were included. References between 2015-2021 were also taken into account.

Results. One of the most representative techniques, AuNP was specifically implemented, together with a magnetic center composed of magnetite, which has as a specific ligand with a C-terminal cysteine domain present in the B-amyloid protein, which adhere directly to the surface of the NPs, characterizing the anomalous protein. Subsequently, by means of nanosensors capable of detecting and measuring different concentrations, these pathologies are identified at an early stage.

Conclusions. Today, along with the advent of biotechnology, it has been possible to design techniques with NPs that allow the identification of specific mutations and provide diagnosis in individuals. In the investigative models of AuNP, it is possible to infer that the capabilities that make them representative focus on their magnetism and biofunctionality, by specifically binding to amyloid peptides and other ligands present in the protein, which are the major components of amyloid plaques used in these studies.
Mammal fauna of Chisinau airport, Republic of Moldova
Authors: NISTREANU Victoria , LARION Alina
Published: January 2022

Introduction. Airport territories are large, containing a high variety of biotopes, mostly open type, and are relatively protected against intense human activity, thus creating favorable conditions for many mammal species that serve as trophic source for many bird species.

Material and methods. The studies were performed during 2012-2014 on the territory of Chisinau airport and within the adjacent ecosystems. The mammals were recorded by direct observations, based on traces and trophic activity on routes ranging from 1 to 3 km. The small mammals were assessed with traps. The bat species were identified according to their flight pattern and using the ultrasound detector.

Results. In the airport, 31 species of mammals were registered: 5 insectivore species, 7 bat species, 14 rodent species, 1 hare species and 4 carnivorous species. The most widespread, common and abundant were the rodents and the fox. Among small rodent species, the most abundant was Apodemus sylvaticus with 51.6%, followed by the Microtus arvalis (38.9%), while on the airport grassland, the field vole dominated with more than 60%. The diet of Athene noctua included predominantly Mus musculus with over 51%, followed by M. arvalis with 23.7%. 7 species are rare and 5 protected – bicolor shrew and 4 bat species.

Conclusions. The airport territory and adjacent ecosystems provide favorable conditions for many mammal species. The presence of rodents favors the occurrence of rather high number of prey birds, which represent a threat for the safety of aircraft flights. The fox can pose direct threat to flight safety.
Development of business models of managing oil service processes in big oil and gas companies
Authors: Isakov Aleksey , Liron Eric , Shtopakov Igor , Semushkina Svetlana
Published: January 2022

The article considers the features of the business model for managing oilfield service processes in big oil and gas companies using the example of PJSC Oil Company «Rosneft». The purpose of the article is to study current business models in oil and gas industry, identify their advantages and disadvantages, and develop recommendations for improving sourcing procedures in accordance with the dynamics and changes in the external environment of companies' functioning. The research applies a variety of scientific methods which include analysis, synthesis and systematization of conceptual and practical aspects of sourcing in the context of the Russian oil and gas industry. The authors provide a critical analysis of theoretical aspects related to the concepts of sourcing, outsourcing and insourcing, which have been in the focus of Russian economic science since the mid-2000s. Special attention is paid to the insourcing model, which is available and used by large companies in capital-intensive industries with long-term investment and production cycles, such as oil and gas. The signs of production and management inefficiency of insourcing are formalized. In terms of transaction costs, a comparison is made between the efficiency and effectiveness of outsourcing and vertical integration. Taking into account the peculiarities and distinctive features of modern business environment, its uncertainty and new challenges for oil and gas producing companies, the authors conclude that strategic outsourcing is most in demand. The results obtained in the study can be used in practice of oil and gas companies, as well as by government bodies in the process of developing a regulatory policy in the relevant area.
La digitalización de los proyectos arquitectónicos en Nuevo León, México. Una mirada a la actualización tecnológica de la práctica profesional de la Arquitectura
Authors: Portillo Ríos Raymundo Alberto
Published: January 2022

El proyecto arquitectónico constituye el quehacer esencial de la práctica profesional de la Arquitectura. El presente trabajo analiza la digitalización de los proyectos arquitectónicos en Nuevo León, México; teniendo como objetivos específicos: describir las fases del proyecto arquitectónico; señalar las herramientas digitales empleadas como soportes en la digitalización; así como identificar las técnicas digitales de representación aplicadas en los proyectos arquitectónicos. El estudio, con enfoque y metodología cuantitativa, descriptiva, transaccional, analizó los datos recabados de 75 profesionales de la Arquitectura, mediante técnicas estadísticas descriptivas. Los resultados arrojaron que en todas las etapas del proyecto arquitectónico, las herramientas digitales más utilizada son el CAD, seguidas por las de modelado y renderizado, y en menor medida por las asociadas al uso de BIM; constituyéndose las técnicas del dibujo digital en 2D y en 3D como las más importantes en todo el proceso, asegurando no solo la digitalización del proyecto, sino el uso progresivo de las tecnologías digitales en la representación y en el hacer arquitectónico.
Lectura crítica e Investigación. Aportaciones de Hugo Zemelman al aprendizaje en la Universidad
Authors: Morales Jesús
Published: January 2022

La lectura crítica y la investigación en Hugo Zemelman, constituyen procesos complejos y de singular importancia para el que se forma en la Universidad; su visión, sugerencias y planteamientos dejan ver a ambos procesos mediados por el pensamiento crítico y epistémico. Este artículo expone las aportaciones de Hugo Zemelman a la praxis de la lectura crítica y a la investigación, destacando su importancia para quien participa de la educación universitaria. Se concluye, que el acercamiento profundo a la realidad supone asumir una actitud capaz de dialogar y cuestionar las posiciones científicas existentes (conocimiento acumulado) que, por estar permeado de propósitos hegemónicos, conduce a la dominación del pensamiento y a la adopción de visiones parciales, reduccionistas e incompletas, las cuales condicionan las formas de ver el mundo y generan respuestas carentes de pertinencia académica y social.
Galactic Foreground Constraints on Primordial B-mode Detection for Ground-based Experiments
Authors: Hervías-Caimapo Carlos , Bonaldi Anna , Brown Michael L. , Huffenberger Kevin M.
Published: January 2022

Contamination by polarized foregrounds is one of the biggest challenges for future polarized cosmic microwave background (CMB) surveys and the potential detection of primordial B-modes. Future experiments, such as Simons Observatory (SO) and CMB-S4, will aim at very deep observations in relatively small (f
sky ∼ 0.1) areas of the sky. In this work, we investigate the forecasted performance, as a function of the survey field location on the sky, for regions over the full sky, balancing between polarized foreground avoidance and foreground component separation modeling needs. To do this, we simulate observations by an SO-like experiment and measure the error bar on the detection of the tensor-to-scalar ratio, σ(r), with a pipeline that includes a parametric component separation method, the Correlated Component Analysis, and the use of the Fisher information matrix. We forecast the performance over 192 survey areas covering the full sky and also for optimized low-foreground regions. We find that modeling the spectral energy distribution of foregrounds is the most important factor, and any mismatch will result in residuals and bias in the primordial B-modes. At these noise levels, σ(r) is not especially sensitive to the level of foreground contamination, provided the survey targets the least-contaminated regions of the sky close to the Galactic poles.
Repurposing – second life for drugs
Authors: Ayyar Porkodi , Subramanian Umamaheswari
Published: January 2022

Drug repurposing refers to finding new indications for existing drugs. The paradigm shift from traditional drug discovery to drug repurposing is driven by the fact that new drug pipelines are getting dried up because of mounting Research & Development (R&D) costs, long timeline for new drug development, low success rate for new molecular entities, regulatory hurdles coupled with revenue loss from patent expiry and competition from generics. Anaemic drug pipelines along with increasing demand for newer effective, cheaper, safer drugs and unmet medical needs call for new strategies of drug discovery and, drug repurposing seems to be a promising avenue for such endeavours. Drug repurposing strategies have progressed over years from simple serendipitous observations to more complex computational methods in parallel with our ever-growing knowledge on drugs, diseases, protein targets and signalling pathways but still the knowledge is far from complete. Repurposed drugs too have to face many obstacles, although lesser than new drugs, before being successful.
Proposals for improvement of Annex I of Directive 92/43/EEC: Sardinia
Authors: Fois Mauro , Bacchetta Gianluigi , Caria Maria Carmela , Cogoni Donatella , Farris Emmanuele , Fenu Giuseppe , Manca Manuela , Pinna Maria Silvia , Pisanu Stefania , Rivieccio Giovanni , Bagella Simonetta
Published: January 2022

The ‘Habitats’ Directive (HD 92/43/EEC) is one of the primary legal tools aiming at conserving nature in Europe. Due to the complex iter to revise it, the habitats listed in the Annex I have been seldom updated after the HD adoption. Basing on already available information and expert knowledge, this paper presents a preliminary list of relevant habitats occurring in Sardinia, not yet considered and worth to be placed in the Annex I. Two new habitat proposals, one habitat new for Italy, and nine new subtypes of already existing HD habitats are here described. Most of the proposed new habitats and subtypes have a limited distribution range, due to the high number of narrow, often endangered, endemic species that characterize them. Being neglected, they are consequently poorly investigated, inconstantly monitored and unprotected. Thus, the main aim of this paper is to promote their conservation through implementation of HD and its interpretation manuals.
Improved Hardy-Rellich inequalities
Authors: Cassano Biagio , Cossetti Lucrezia , Fanelli Luca
Published: January 2022

We investigate Hardy-Rellich inequalities for perturbed Laplacians. In particular, we show that a non-trivial angular perturbation of the free operator typically improves the inequality, and may also provide an estimate which does not hold in the free case. The main examples are related to the introduction of a magnetic field: this is a manifestation of the diamagnetic phenomenon, which has been observed by Laptev and Weidl in [21] for the Hardy inequality, later by Evans and Lewis in [9] for the Rellich inequality; however, to the best of our knowledge, the so called Hardy-Rellich inequality has not yet been investigated in this regards. After showing the optimal inequality, we prove that the best constant is not attained by any function in the domain of the estimate.
Uniform Approximation Property of Frames with Applications to Erasure Recovery
Authors: Chen Ting , Lv Fusheng , Sun Wenchang
Published: January 2022

In this paper, we introduce frames with the uniform approximation property (UAP). We show that with a UAP frame, it is efficient to recover a signal from its frame coefficients with one erasure while the recovery error is smaller than that with the ordinary recovery algorithm. In fact, our approach gives a balance between the recovery accuracy and the computational complexity.
Analysis of nonlinear time-fractional Klein-Gordon equation with power law kernel
Authors: Saifullah Sayed ,   Department of Mathematics, University of Malakand, Chakdara, Dir(L), Khyber Pakhtunkhwa, Pakistan, Ali Amir , Khan Zareen A. ,   Department of Mathematical Sciences, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia
Published: January 2022

We investigate the nonlinear Klein-Gordon equation with Caputo fractional derivative. The general series solution of the system is derived by using the composition of the double Laplace transform with the decomposition method. It is noted that the obtained solution converges to the exact solution of the model. The existence of the model in the presence of Caputo fractional derivative is performed. The validity and precision of the presented method are exhibited with particular examples with suitable subsidiary conditions, where good agreements are obtained. The error analysis and its corresponding surface plots are presented for each example. From the numerical solutions, we observe that the proposed system admits soliton solutions. It is noticed that the amplitude of the wave solution increases with deviations in time, that concludes the factor $ \omega $ considerably increases the amplitude and disrupts the dispersion/nonlinearity properties, as a result, may admit the excitation in the dynamical system. We have also depicted the physical behavior that states the advancement of localized mode excitations in the system.
Entity recognition of Chinese medical text based on multi-head self-attention combined with BILSTM-CRF
Authors: Li Chaofan ,   School of Medical Information and Engineering, Xuzhou Medical University, Jiangsu 221004, China, Ma Kai
Published: January 2022

Named entities are the main carriers of relevant medical knowledge in Electronic Medical Records (EMR). Clinical electronic medical records lead to problems such as word segmentation ambiguity and polysemy due to the specificity of Chinese language structure, so a Clinical Named Entity Recognition (CNER) model based on multi-head self-attention combined with BILSTM neural network and Conditional Random Fields is proposed. Firstly, the pre-trained language model organically combines char vectors and word vectors for the text sequences of the original dataset. The sequences are then fed into the parallel structure of the multi-head self-attention module and the BILSTM neural network module, respectively. By splicing the output of the neural network module to obtain multi-level information such as contextual information and feature association weights. Finally, entity annotation is performed by CRF. The results of the multiple comparison experiments show that the structure of the proposed model is very reasonable and robust, and it can effectively improve the Chinese CNER model. The model can extract multi-level and more comprehensive text features, compensate for the defect of long-distance dependency loss, with better applicability and recognition performance.
Integrative system biology and mathematical modeling of genetic networks identifies shared biomarkers for obesity and diabetes
Authors: Bima Abdulhadi Ibrahim H. ,   Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia, Elsamanoudy Ayman Zaky , Albaqami Walaa F , Khan Zeenath , Parambath Snijesh Valiya , Al-Rayes Nuha , Kaipa Prabhakar Rao , Elango Ramu , Banaganapalli Babajan , Shaik Noor A. ,   Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt,   Department of Science, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia,   Division of Molecular Medicine, St. John's Research Institute, Bangalore, Karnataka, India,   Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia,   Princess Al-Jawhara Al-Brahim Center of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia,   Department of Genetics, College of Science, Osmania University, Hyderabad, India,   Department of Genetic Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
Published: January 2022

Obesity and type 2 and diabetes mellitus (T2D) are two dual epidemics whose shared genetic pathological mechanisms are still far from being fully understood. Therefore, this study is aimed at discovering key genes, molecular mechanisms, and new drug targets for obesity and T2D by analyzing the genome wide gene expression data with different computational biology approaches. In this study, the RNA-sequencing data of isolated primary human adipocytes from individuals who are lean, obese, and T2D was analyzed by an integrated framework consisting of gene expression, protein interaction network (PIN), tissue specificity, and druggability approaches. Our findings show a total of 1932 unique differentially expressed genes (DEGs) across the diabetes versus obese group comparison (p≤0.05). The PIN analysis of these 1932 DEGs identified 190 high centrality network (HCN) genes, which were annotated against 3367 GO terms and functional pathways, like response to insulin signaling, phosphorylation, lipid metabolism, glucose metabolism, etc. (p≤0.05). By applying additional PIN and topological parameters to 190 HCN genes, we further mapped 25 high confidence genes, functionally connected with diabetes and obesity traits. Interestingly, ERBB2, FN1, FYN, HSPA1A, HBA1, and ITGB1 genes were found to be tractable by small chemicals, antibodies, and/or enzyme molecules. In conclusion, our study highlights the potential of computational biology methods in correlating expression data to topological parameters, functional relationships, and druggability characteristics of the candidate genes involved in complex metabolic disorders with a common etiological basis.
TRANSITION FROM TRADITIONAL COB CONSTRUCTION TO 3D PRINTING OF CLAY HOMES
Authors: Alqenaee Amnah Y. , Memari Ali M. , Hojati Maryam
Published: January 2022

3D printing of cementitious material can provide an affordable, sustainable, and optimized approach for the construction of homes, without compromising quality or craftsmanship. While most of the current research and development efforts in this field are focused on cement-based concrete printing, this paper focuses on the current state-of-the-art literature review of designing and developing a sustainable clay-based mixture design that mainly includes clay, sand, straw, lime, and water. The goal of this paper is to bridge the gap between typical traditional earth construction, specifically cob construction, and emerging 3D printing of cementitious materials. The specific objective of this paper is to offer some possible changes in the typical cob mixture so that it can be used for 3D printing of clay-based mixtures with sufficient flowability, buildability, strength, and open time (i.e., the time period between printing of one layer and printing of another layer deposited on a layer below). The paper describes typical clay-based mixtures and their traditional process and then specifies the challenges in going from traditional cob construction to advanced computer-controlled robotic 3D printing.
E-Commerce Adoption Among Micro, Small, and Medium Enterprises in Brunei Darussalam
Authors: Almunawar Mohammad Nabil , Auzzali Anizzah , Oseli Nur‘Amalina Haji , Ariff Wan Zaleha Ariff Md Zain
Published: January 2022

The advancement of the Internet has enabled firms including micro, small and medium-sized enterprises (MSMEs) in Brunei Darussalam (Brunei) to adopt e-commerce. E-commerce has helped firms to easily buy and sell their products or services online. The advancement of the Internet and e-commerce has brought many benefits to the firms especially the MSMEs as it could help to reduce cost, enhance the firm's relationship with their customers and/or suppliers and increase business opportunities. To stay competitive, MSMEs must be aware of the potential benefits that e-commerce could bring. Moreover, before the firms have decided to adopt e-commerce, there are several factors that they should consider. This study aims to find out the factors that could affect the MSMEs' decision to adopt e-commerce by applying the technology-organizational-environmental (TOE) framework.
Does Cloud Computing Influence Enterprise Performance?
Authors: Chang I-Cheng , Liu Chuang-Chun , Wu Tsai-Ling
Published: January 2022

The emergence of the cloud computing service has resulted in the entry of many companies into the market, with numerous competitors for cloud computing leading the technological trend. Recent studies have mainly focused on the characteristics of cloud computing, whereas its influence on firm performance has been rarely discussed. Therefore, this study aimed to fill this empirical research gap. This current study examined whether investments in cloud computing can influence firm performance and whether cloud computing influences firm performance. Data were collected using a questionnaire. Structural equation modeling provided evidence supporting the theoretical model. The results of this study revealed that cloud computing investment influences firm learning and growth performance, internal processes, and finances. The theoretical and practical contributions and implications of these findings are described in this paper.